LOCUS       DBMDTB010000001       103058 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_100_length_103058_cov_11.456064, whole genome shotgun
            sequence.
ACCESSION   DBMDTB010000001 DBMDTB010000000
VERSION     DBMDTB010000001.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 103058)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 103058)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..103058
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_100_length_103058_cov_11.456064"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..3852
                     /locus_tag="ACZPB4_00005"
     CDS             <1..3852
                     /locus_tag="ACZPB4_00005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-2-macroglobulin family protein"
                     /protein_id="HIR1096653.1"
                     /translation="RPTFQAYFLPIKGDIAFGDSVTIQGKAATFSGVSLPSGDVTWRI
                     TRRPFLLWRYFRPSAPTQVAEGSTTLSGDGTFNVSFRPQKEEDTNPYASAYQTYEVSA
                     TVTDSKGETQEANYTFSVGESSIVLFTNLPPQIEKDSVKAVVEARTINGEMVSTSGTF
                     KIVELIANRSDKNSGESYQEGKQVASGSFTSGKEISPAIFNPLPSGRYRILVEAKDSQ
                     GRQSKNQSDFILYGKNDKRPPVFTHTWLLKEKTTCLPGEEAEIVFGTSDKDAYVLYEW
                     FAGNNRIHHELIKLSDANHRFNIPFKPEYGEGIIVSFTFVKEGELYITQVPVELQLPN
                     RQLTIKPITFRDRLLPGSKESWKFRITDADSTIVSAEVLTSMYDASLDKIIPFNWYFS
                     PRRTILLQAPRFSTGAGFQRSYQYDQTEAKYIKVPQYQYDRLNWFGLFNEIVIRGYGS
                     SNRAFATGGIMLKSAAAPVVAESMNIMEDSAVLEEPSVESTEGEPVFSLSDPFAKESS
                     LPVSPEQTRRNFAETAFFYPTLQTNEEGDVFVNFTLPESNTTWKLQLLANTQDLKYGL
                     LTKEVISSKPLMVLPNLPRFVRQGDEVSISTQVINNSKEAVSGRVRIELFDPATDQPI
                     ICLSKSQRPFELQPDSIATVSWMIPVPKQINLLGVRILADSEKGSDGEQQIVPVLSNQ
                     LLITESTPFYLLKEGEKQIRISGNSEGATPFRLTLEMTGNPIWYAVQALPTITQPNND
                     NILSWFAAYYSNTLASYIAQAHPRIQKVINQWTAQGGNASTLYSNLEKNQELKNILLE
                     ETPWVLAADNETEQKQRLSLLFDLNRADGLREAALQQLIQQQNEEGGWSWFKGFPASR
                     AITLSILKGMSQLVQLNAIQYGQAEKEMQMKALKFLDKSMQTDYENLLKYDKKWQNAW
                     PSPEQVEFLFVRSSYRDIPELGDAREAIRFYTNQAEKHWNQYSLISKGEIALLMHRNG
                     KKEVATAILTWLKKTATISEEKGMYWANNRRGSDYFTSPIDTHCLLMSVFNEIAPDTQ
                     NTNRMKQWLLNQKRTQNWESVPATVNAIYALLLTGSDWLNTQNTCVATWDGKTYSTAE
                     GEIATGYLKTILPNEPANNSANPVLSIRKEGNTPAWGAVYEQYFQEIDKVKGQKGVLS
                     VEKKLFVETNNGTNRQIRPVTPEQPLRIGDKVIVRLTIRTDREMNYVFLKDLRAGCFE
                     PADQLSGPESRDGIWYYRSPKDVSENFFINRLPEGTFVLEYPVYVSRSGEYAGGISTI
                     QCMYAPEFVSHTAGESLRIMP"
     gene            4045..4422
                     /locus_tag="ACZPB4_00010"
     CDS             4045..4422
                     /locus_tag="ACZPB4_00010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1573 domain-containing protein"
                     /protein_id="HIR1096654.1"
                     /translation="MKQIVFIFMAILLATGMASAQKKAVISAETTSFDFGTIKEADGK
                     VSHTFEVSNTGDMPLVITRVIASCGCTTPEWPKEPVAPGKKAQIKVTFDPAGRPGPFT
                     KTISVYSNGKTGSFIMNIRGEVE"
     gene            4450..5559
                     /locus_tag="ACZPB4_00015"
     CDS             4450..5559
                     /locus_tag="ACZPB4_00015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1573 domain-containing protein"
                     /protein_id="HIR1096655.1"
                     /translation="MLNIKRLILALTAIISITTAWAQQGAQILSDELTYNFGTIAEAD
                     GFASHTFTIKNTGDAPLVITRVTASCGCTRPEWTKSPIAPGKTGEVKITYNPKGRPGP
                     FYKTVSIFSNGKKGSYSLAIKGNVTPKPSQPVFTYPYSIGDLKLHTKTVLFSSIRPEE
                     TLGEKINIKNEGKTSATIHLGKVPHYLNVQVNPATLQPDEVGAITILMDAKVLKRKGR
                     VSTLLPVMVQSTGKKEVSGEIQISANVIDNFSKLSAADKAQAPIAELSGTLLEFGKLP
                     NKKSIVPLIGGKVSGTFEITNAGKTPLTIYSVTCDDERVDLSGGKKELKPGATATFKV
                     TLRPKEIKTKLEALINVVCNDPNGPIRLIKVTAYK"
     gene            5569..6666
                     /gene="meaB"
                     /locus_tag="ACZPB4_00020"
     CDS             5569..6666
                     /gene="meaB"
                     /locus_tag="ACZPB4_00020"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylmalonyl Co-A mutase-associated GTPase
                     MeaB"
                     /protein_id="HIR1096656.1"
                     /translation="MEHPENDDQYKGLKVNKGIADVPTVNPYIKKRVQRKVYTPSEFV
                     EGILKGNITILSQAVTLVESSKHEHQQVAQEIIEKCLPFAGKSVRIGITGVPGAGKST
                     SIDSFGMHLINQGRKLAVLAIDPSSERSKGSILGDKTRMEALSREKNAFIRPSPSAGS
                     LGGVARKTRETIVLCEAAGFDTVFVETVGVGQSETAVHSMVDFFLLIQLAGTGDELQG
                     IKRGIMEMADGIIINKADGDNIEKANLAAAQFRNALHLFPPSESGWFPKVLTYSGYYN
                     LGIKEIWDMVGEYMEFTKKNGYFDYKRNEQAKYWMYESINDTLRDKFYHNPAVEGMLE
                     QTEKQVLNNEISSFVAAKRMIDLFLDNIATK"
     gene            complement(6716..8188)
                     /locus_tag="ACZPB4_00025"
     CDS             complement(6716..8188)
                     /locus_tag="ACZPB4_00025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolB family protein"
                     /protein_id="HIR1096657.1"
                     /translation="MRKMYIIRCICLWMILGLMACSGPVRIQKNLEVKPEIFPDYVDV
                     TIPPNIAPLNFKLKDVCTEARAILECGPEKLEIKTGKDACFVIPASGWKRLLRAASGN
                     HLNVTVQAFVNDEWIAYVPFIIKVAKEPVDGWLAYRLIEPGYELWNRMGIYQRNLENY
                     TENAIIENKMSGNNCMNCHSFCMQNPEKMLFHMRETYSCTLLIDGDKVEKLNTKTDQT
                     LSPLVYPSWHPSGKYVAFSVNKTKQAFHMNDRNRVEVFDSASDVVVYDTQKHEIVTSP
                     LLSSEGAFETFPTFSPDGNTLYFCSAKARTMPKEYDQVRYDLCSVSFDPATRRFGTVV
                     DTLYKASEIDKSVSFPRVSPDGKYLLYTLSGYGNFSIWHKDADLYMIDLSTLQSYPLE
                     AANSDDVESYHSWSSDSRWIVFSSRRIDGLYTRPFIAYIDEKGQACKPFLLPQKDTDF
                     YFRFMKSYNIPEFITGEVKRQGRALAVKAKEDKGVDVRFK"
     gene            complement(8192..9943)
                     /locus_tag="ACZPB4_00030"
     CDS             complement(8192..9943)
                     /locus_tag="ACZPB4_00030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6057 family protein"
                     /protein_id="HIR1096658.1"
                     /translation="MKKYSGVALHVIVFVFLFIFLRIFSEYHFYCVEQNQLFQLTPIF
                     IIDKLMQPGGLAMVLSGCLVQFFILPNVGAMITAALLTSLGALFWAILKRIDPRSHGI
                     LWAWLPVLSLLFVQWDFNYRFQGTVAFGMMLLALYLVLGIRNFIPRLIASLFASLLLF
                     GLAGPVSLLFALSMVGYEAMSRTPRWYYSAILPMIVLILGGLCVRYSVIGEYRFVFLP
                     DSYYYFRLVPDKVIYFSWIAFYAALVVTCLCKNKESWAGKKRLALGISQFIILGLIFW
                     KGFDLYGEQKSYRLKMMDYFTRTEQWDRILVSCKEPTTNQLYLCYQNMALARKGILAD
                     EAFKYTQHGPRGLMVAWNKSTTISALLSDVYFTMGNVAAAQEMAFESNIGALCDGNPR
                     MTQRLVQTNLIYGAYPVAEKYIAVLENTFYYKDWAKAQRKFLYNDEAVETDPLLGNMR
                     RNLLAENHLIQMDGFDTDLIRLAEQNPSNKAAFHYAGVFYLLAKDVTRFKTLVETYYG
                     TDLLPSLPVSFQEAVIILSEKDPDYWKRFGVSESIVGRFTDYKRQVLAGRNNSNALPG
                     LMYRSYGDTYWYYYMFK"
     gene            complement(10025..11005)
                     /gene="pfkA"
                     /locus_tag="ACZPB4_00035"
     CDS             complement(10025..11005)
                     /gene="pfkA"
                     /locus_tag="ACZPB4_00035"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007654871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006002 - fructose 6-phosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HIR1096659.1"
                     /translation="MSTVKCVGILTSGGDAPGMNAAIRAVTRSAIYNGMRVKGIYRGY
                     KGLILDEIEEFKTQNVSNIIQRGGTILKTARCVEFKTPEGRKQAYDKLQEHGIDALIA
                     IGGDGTLTGARIFAQEFNFPIVGLPGTIDNDLYGTDTTIGYDTALNTIMECVDKIRDT
                     ATSHDRLFFVEVMGRDAGFLALNGAIASGAEAAIIPEISLEKDQLAEMIENGFRKSKN
                     SSIVLVAESEVTGGAMGVAERVKKEYPQFDVRVSILGHLQRGGSPTAQDRILATRMGV
                     AAIDALLDDQRNVMMGIQNDQIVYVPFSKAIKNDKPINRDLLNTLRVSSI"
     gene            complement(11103..11975)
                     /locus_tag="ACZPB4_00040"
     CDS             complement(11103..11975)
                     /locus_tag="ACZPB4_00040"
                     /EC_number="1.17.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051745 - 4-hydroxy-3-methylbut-2-enyl
                     diphosphate reductase activity [Evidence IEA];
                     GO_process: GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA];
                     GO_process: GO:0050992 - dimethylallyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="HIR1096660.1"
                     /translation="MIEVEIDKDSGFCFGVVTAIESAERELGNTDTLYCLGDIVHNSL
                     EVERLEHMGLHTIDHDGLSKLRDRKVLLRAHGEPPSTYSLAKRNNITIIDATCPVVLR
                     LQRKIHKCYQETRANNTQLVIYGKKGHAEVNGLVGQTEGTAIVIEKIEDLDRLDFTRA
                     ISLFSQTTKSLDGFKAVVAEIKQRMAEGVEFNYYDTICRQVANRLPNIKAFASSHDWV
                     YFVAGRKSSNGKMLFEECRKANPNTLFISEVSEITEPLPEGVRRVGVCGATSTPKWLM
                     EEVAVRIKELNASE"
     gene            complement(12160..12849)
                     /gene="cmk"
                     /locus_tag="ACZPB4_00045"
     CDS             complement(12160..12849)
                     /gene="cmk"
                     /locus_tag="ACZPB4_00045"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0036431 - dCMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HIR1096661.1"
                     /translation="MKKIVIAIDGHSSSGKSTMAKDLAKEIGYTYIDTGAMYRAVTLY
                     CIQHGFFEGEKIKEEELKASIHDIDISFRLNAETGRPDTYLNGVNVEKEIRGMEVADK
                     VSPVATLGFVRRALVAKQQEMGKAKGIVMDGRDIGTVVFPDAELKLFVTASPEVRAKR
                     RVDELEAKGIPASYEEVLENVKKRDYIDSTREESPLRQADDALVLDNSHMTLEEQKTW
                     LLEQYHKAIGS"
     gene            complement(12870..13880)
                     /gene="porQ"
                     /locus_tag="ACZPB4_00050"
     CDS             complement(12870..13880)
                     /gene="porQ"
                     /locus_tag="ACZPB4_00050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IX secretion system protein PorQ"
                     /protein_id="HIR1096662.1"
                     /translation="MRNKLFILILFVVTLSVSAQNGSEAYTFLRFPTSTRANALGGHT
                     VALVERDPSLIFHNPALLGAEMDGMINLNYMNYISDINVGSALFTKAHGEKGAWGVGA
                     TFISYGDIKEVLPDNVVTGASLSAKDISVNGFYSRDLNERWRGGLSLKFLYSGLADYT
                     SIGLCVDAGLSYYNSDKGFSFGFALKNIGAQLKAYEDERQKMPWDIQMGITQKMAHAP
                     IRFSLTAQYLNRWKFDYIDNTDKEYDGDSFVKTLAKHFIIGVDFIPSENFWVGVGFNP
                     KVNMDMKLKGGGSFSGFSAGAGVRIKMFDVGFSLAKYHPSAMSMMISVSTTLADFKKV
                     TE"
     gene            14088..14780
                     /locus_tag="ACZPB4_00055"
     CDS             14088..14780
                     /locus_tag="ACZPB4_00055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_function: GO:0031992 - energy transducer activity
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy transducer TonB"
                     /protein_id="HIR1096663.1"
                     /translation="MEIKKSPKADLERGKSLSILMGFVVGLAVLFVGFEWSTRDVMVV
                     QASEGVADIIAEEEVEITRPENTPPPPPPPPAPVVTEVLNVVEDDVELEQQDILSSED
                     NQQEAQTAVYTPPAVVEEEEESAQQIFTVVEEMPKFPGGDAELLKFIAKSIKYPVIAQ
                     ENGIQGRVICAFVVNRDGSVVDAEVLRGVDPSLDKEALRVIGTMPKWTPGKQRGKPVR
                     VKYTVPITFRLQ"
     gene            14861..15835
                     /locus_tag="ACZPB4_00060"
     CDS             14861..15835
                     /locus_tag="ACZPB4_00060"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HIR1096664.1"
                     /translation="MLAFENILQRIESEISQLQFTNPPKSLYEPIEYILSLGGKRIRP
                     ALTLMACNIYNNSIENAIKPALGLEVFHNFTLLHDDLMDEADKRRNKPTVHKVWNANT
                     AILSGDAMLIAAYQLIGSTEHGHLKQVLDLFTQTAAEICGGQQFDMEFESRMDVSEEE
                     YIEMIRLKTAVLLACSLKTGALLGGASQEDAGNLYAFGINIGLAFQLQDDLLDVYGDT
                     ATFGKNIGGDILCNKKTFLLINALRLANKEQAEALRSWMDKKEFDPAQKIQAFTSIYN
                     ELQLKQLTENKIQAYYDASVENLKALQVAPEKLTILKEVCDHLMHRQS"
     gene            15839..16624
                     /locus_tag="ACZPB4_00065"
     CDS             15839..16624
                     /locus_tag="ACZPB4_00065"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012056149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004536 - DNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HIR1096665.1"
                     /translation="MRLIDTHCHLYLEDFDPEQDELAQKAKDSGIDTLLLPNVDLTTI
                     DRMHDLCDRYPEFAFPMMGLHPTSVDSNYIDILKQTESYLSKRTYCGIGEIGIDLYWD
                     KTYLKEQQIVFEEQLRWSIDLNLPVAIHTRDAYPEVLECIHKVGAERLKGVFHSFTGT
                     TEELEEIKKLPTFKIGINGVVTFKNSKLSEVIRQTDLKKILLETDAPYLSPVPYRGRR
                     NEPTYIWKTAEKVAETFGLTLEETVNATRKNTLELFKSVNKPI"
     gene            16772..16859
                     /locus_tag="ACZPB4_00070"
     tRNA            16772..16859
                     /locus_tag="ACZPB4_00070"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:16806..16808,aa:Ser,seq:gga)
     gene            16940..17683
                     /locus_tag="ACZPB4_00075"
     CDS             16940..17683
                     /locus_tag="ACZPB4_00075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005648199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015252 - proton channel activity
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MotA/TolQ/ExbB proton channel family protein"
                     /protein_id="HIR1096666.1"
                     /translation="MKKLFAKAFLGLCALGTSTVAFAQDAADAATAVEGGMYQALKTK
                     FIEGGADFMSLVAIALIFGLAFCLERIIYLNLAETNSSKLLKGIEDALDKGDVEGAKA
                     IARDTRGPIASIAYQGLMRIDQGIDVVEKSIVSYGGVQGGLLEKNMSWITLFIAMAPS
                     LGFLGTVVGMIMAFDKIEQVGDISPTVVAGGMKVALITTVGGLIVALILQVFYNYLLS
                     KLEAILNQMEDASISLLDLVIKYNVKFKK"
     gene            17693..18166
                     /locus_tag="ACZPB4_00080"
     CDS             17693..18166
                     /locus_tag="ACZPB4_00080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1096667.1"
                     /translation="MAVTKIRKISSWTLLISSIISIIVLGMFYAGGVVDPAAEMKEPI
                     YTGLLINWTSVLFFVTIISTMLFAVWQFLTLLKTNAKSAIMSLVVLVCFVAVLFITYT
                     MGDATPLTGLNADSQVYNTPGWLKITDMWIMSTIVLLVLIVACVVWGSVKRIMGK"
     gene            18199..18789
                     /locus_tag="ACZPB4_00085"
     CDS             18199..18789
                     /locus_tag="ACZPB4_00085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ExbD/TolR family protein"
                     /protein_id="HIR1096668.1"
                     /translation="MGKKRKTPGINGSSSADIAFMLLIFFLITTSMDTDKGLARRLPP
                     PVPKDQKNDTDVDIKKRNLLVVLINSNNQILCGDQFVDIKQLKERIKEFIDNPYNDEH
                     KPERVEADVPFFGKMMVTKNHVISLQNDRGTEYQAYIDVQNEIAAAYNELRNKVSKEK
                     FGKNFADLDEEQQKAVQQIYPQKISEAEPKNYGGKK"
     gene            18789..19259
                     /locus_tag="ACZPB4_00090"
     CDS             18789..19259
                     /locus_tag="ACZPB4_00090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ExbD/TolR family protein"
                     /protein_id="HIR1096669.1"
                     /translation="MGKFSKAGGREMPELNTSSLPDLVFAFLFFIMMVTSMREVTLKV
                     EFHAPQATELQKLEKKSLVTFIYVGKPTRDLRAKMGSETRIQLNDAFAETSEIQDYIA
                     QEKSSMKEEDQPFMTVSIKADKETKMGTITDIKQALREAYALKISYSAAQRVDE"
     gene            complement(19312..19860)
                     /locus_tag="ACZPB4_00095"
     CDS             complement(19312..19860)
                     /locus_tag="ACZPB4_00095"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIR1096670.1"
                     /translation="MSEDHVIISKPVREIADPLLDLVEKTYTSSFPEEERRDFSLVRK
                     LLEEDSRFEMYALLRDGIYVGFITGWQFEGFVYAEHFAIDESARNGGIGAKAMTSFLA
                     LHEDPVVLEVEMPTEEMSKRRIGFYERLGFVLDHHVYFQPPYRRGEALLEMRLMTHGE
                     LDLERSFKRVKTIIHQNVYGVK"
     gene            20005..20475
                     /locus_tag="ACZPB4_00100"
     CDS             20005..20475
                     /locus_tag="ACZPB4_00100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HIR1096671.1"
                     /translation="MAHHQLDELDEKILKLIIGNARMPFLEVARECNVSGAAIHQRIQ
                     KLTNLGVIKGSEFIVDNTKVGYETCAYMGLFLKSPGQFPSVTEALLQIPEVVECHYTT
                     GQYDLFIKIYAKNNQHLLSIIHNKLQPLGLARTESLISFKEAFKRQIPIDLDDD"
     gene            complement(20559..21965)
                     /gene="asnS"
                     /locus_tag="ACZPB4_00105"
     CDS             complement(20559..21965)
                     /gene="asnS"
                     /locus_tag="ACZPB4_00105"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005839184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004816 - asparagine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006421 - asparaginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HIR1096672.1"
                     /translation="METIKRTKIVDVLKSEAFGTTVNVKGWVRTRRGSKQVNFIALND
                     GSTINNVQIVVDVDKLGDEFLKPITTGASISVNGILTQSQGKGQSVEIQATEIEIFGT
                     ADPATYPLQKKGHSMEFLREIAHLRPRTNTFGAVFRIRHNMAYAIHKFFHDRGFFYFH
                     TPIITASDCEGAGQMFQVTTKNLYDLKKDENGSIIYEDDFFGKQASLTVSGQLEGELA
                     ATALGQIYTFGPTFRAENSNTPRHLAEFWMIEPEVAFNDITDNMELAEEFIKYCVQWA
                     LDNCMEDIKFLNDMFDKELIARLEGVLKDSFVRLPYTEGIKILEEAVAKGHKFEFPVY
                     WGVDLASEHERFLVEDHFKRPVILTDYPKEIKAFYMKQNEDGKTVRAMDVLFPKIGEI
                     IGGSEREADYDKLMTRIDELGIPMKDMWWYLDTRRFGTVPHSGFGLGFERLLLFVTGM
                     ANIRDVIPFPRTPNNAEF"
     gene            complement(21981..23468)
                     /locus_tag="ACZPB4_00110"
     CDS             complement(21981..23468)
                     /locus_tag="ACZPB4_00110"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_function: GO:0140098 - catalytic activity, acting on
                     RNA [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HIR1096673.1"
                     /translation="MSTEERDESQPRPKKVIPSIRRENTDQEGERRPYNQGYNKPEGS
                     YERRPYRSYGENNRPSYGDRPSRPRSYDNNREGGYGNNREGGYGNSRPSYGNNRDGGY
                     GNNRPSYGNNREGGYNSGRSSYGNNRPSYGNGGGQYNRPSRPNYDGPAKAYSTSPSGE
                     GMSADGMKKRRPRVGDTRVDYNDSRSSGGDGYAPRRSYGNDNSYGGNRQGGGGYGNNR
                     RPSYNNNRRSGGGGGFQRQQGYNMRPKQIKYKEVLADPNEPIRLNKFLSNAGVCSRRE
                     ADEFIQKGAVKVNDVVVTELGTKITRQDVVTFNEKPVQIESKVYIVLNKPKNCVTTSD
                     DPQERLTVMDLVKNACQERIYPVGRLDRNTTGVLLLTNDGDLASKLTHPSFKKKKIYH
                     VWLDKNVAIEDMEKIANGLELEDGEIHADAISYASEDDKSQVGIEIHSGRNRIVRRIF
                     ESLGYHVTKLDRVYFAGLTKKNLGRGKWRYLNEREVNALRMGAFE"
     gene            complement(23528..24871)
                     /gene="purB"
                     /locus_tag="ACZPB4_00115"
     CDS             complement(23528..24871)
                     /gene="purB"
                     /locus_tag="ACZPB4_00115"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016278592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA];
                     GO_process: GO:0006188 - IMP biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HIR1096674.1"
                     /translation="MVLSTLTAISPVDGRYRNKAENLAAYFSEYALIKYRVRVEIEYF
                     ITLSEFLPQLSELNAAEVKKGLRKIYQEFTEEDALRVKEIESVTNHDVKAVEYFIKEK
                     TNHFLAEKYHEFIHFGLTSQDINNTSVPLSIKDALQEVYYPGLEEVIGALKKYAEEWM
                     DIPMLAKTHGQPASPTRLGKEVMVFVYRLEQQLALLKAVPISAKFGGATGNFNAHHVA
                     YPEYDWRAFGNKFVSEVLGLKREEWTTQISNYDNLAAIFDGLKRINTILIDLNRDFWQ
                     YISMEYFKQKIKAGEIGSSAMPHKVNPIDFENAEGNLGIANAILEHLATKLPVSRLQR
                     DLTDSTVLRNVGVPLAHIEIAFKSLTKGLGKLLLNENALSRDLNNCWAVVAEGIQTVL
                     RREGYPKPYEALKALTRTNQTVTEQSIKEFIETLNVSDRIKDELRAITPHNYTGI"
     gene            25108..25182
                     /locus_tag="ACZPB4_00120"
     tRNA            25108..25182
                     /locus_tag="ACZPB4_00120"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:25143..25145,aa:Val,seq:tac)
     gene            25216..25290
                     /locus_tag="ACZPB4_00125"
     tRNA            25216..25290
                     /locus_tag="ACZPB4_00125"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:25251..25253,aa:Val,seq:tac)
     gene            25325..25399
                     /locus_tag="ACZPB4_00130"
     tRNA            25325..25399
                     /locus_tag="ACZPB4_00130"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:25360..25362,aa:Val,seq:tac)
     gene            complement(25511..25948)
                     /locus_tag="ACZPB4_00135"
     CDS             complement(25511..25948)
                     /locus_tag="ACZPB4_00135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DoxX family protein"
                     /protein_id="HIR1096675.1"
                     /translation="MSAFYKFLFPMKPDGTAISLLLLALRLLFGGLLLSHGIQKWTNF
                     ESMSAAFPDPLGVGHSVSLGLAIFGELFCSIGFILGALYRLAMIPMIFTMGVAFFVIH
                     GNDPFSLKELAFVYLVIFILMYIAGPGKFSLDRLIAVLLSQKR"
     gene            26358..26936
                     /locus_tag="ACZPB4_00140"
     CDS             26358..26936
                     /locus_tag="ACZPB4_00140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004311506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HIR1096676.1"
                     /translation="MLLEKLLKGFNYSTSTFNLKESKLFDQYFERILISKGTFLVKEG
                     EIERYSYFVFDGILRCWLLNHKGEEQIFWFCKEGTFSMSNISFTLQTKSAFNVQTIVD
                     SVIYRIDKKQENELYTAIPKVKTVFEDLNAILLNKLLKRNIDLIKYSPEQYYLQMIEE
                     YGITLNYIPLKDIASYLGITPQALSRIRKRIF"
     gene            27001..27423
                     /locus_tag="ACZPB4_00145"
     CDS             27001..27423
                     /locus_tag="ACZPB4_00145"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008668524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIR1096677.1"
                     /translation="MIKKIKVTDHPRLMEIWESSVLNTHDFLKEEDFLYYKEQLPVYF
                     QHVTLFGFEQEGILVGFMGIAKGNLEMLFIDNNYRGIGIGKKLITYAIDNLQVTKVDV
                     NEQNNQAVGFYKHIGFNTYKRSDLDGEGKEYPILHMRL"
     gene            complement(27487..27560)
                     /locus_tag="ACZPB4_00150"
     tRNA            complement(27487..27560)
                     /locus_tag="ACZPB4_00150"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(27524..27526),aa:Arg,seq:ccg)
     gene            27757..28794
                     /gene="asnA"
                     /locus_tag="ACZPB4_00155"
     CDS             27757..28794
                     /gene="asnA"
                     /locus_tag="ACZPB4_00155"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005678753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004071 - aspartate-ammonia ligase
                     activity [Evidence IEA];
                     GO_process: GO:0070981 - L-asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HIR1096678.1"
                     /translation="MSYLIKPAGYKALLNLSQTEMGIKKIKDFFQQNLSSELRLRRVT
                     APLFVLKGMGINDDLNGTERAVTFPIKDLNDSKAEIVHSLAKWKRLTLADYHIEEGYG
                     IYTDMNAIRSDEELGNLHSLYVDQWDWERVMSESERKIDFLKEIVRRIYAAMVRTEYL
                     VYEMFPQIRPTLPQQIHFIHSEDLLQKYPTFTPKEREDAITKEYGAVFIIGIGCSLSN
                     GEKHDGRAPDYDDWSTIAENGQTGLNGDLLVWDDVLNRSMELSSMGIRVNKEALLRQL
                     DICKAGEKKELYFHKRLLSGELPQSIGGGIGQSRLCMFYLRKAHIGEIQASIWPEEMR
                     KEARAAGMMLI"
     gene            28816..29478
                     /gene="ung"
                     /locus_tag="ACZPB4_00160"
     CDS             28816..29478
                     /gene="ung"
                     /locus_tag="ACZPB4_00160"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008759768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_function: GO:0016799 - hydrolase activity, hydrolyzing
                     N-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HIR1096679.1"
                     /translation="MDVKIEESWKKRLADEFEKDYFKQLTDFVKQEYRQGTVYPPGPY
                     MFNAFEHCPFDKVKVVILGQDPYHEPGQAHGLCFSVQDGVPFPPSLINIFKEIQDDLG
                     HPVPTTGNLIRWADQGVLLLNATLTVRAHQAGSHQNRGWETFTDAVIHRLAAERSHIV
                     YILWGSYAQKKGAFIDSSRNLVLKSAHPSPLSAYRGFFGNKHFSKANDYLIATGQTPI
                     EW"
     gene            complement(29542..32286)
                     /locus_tag="ACZPB4_00165"
     CDS             complement(29542..32286)
                     /locus_tag="ACZPB4_00165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative LPS assembly protein LptD"
                     /protein_id="HIR1096680.1"
                     /translation="MFLIYRVLIILFVFLLGGLGVQAQEIVAPADSLAQTDSLLVAPT
                     DSTTLAGDSIPEKQTGLDAPVSYQATDSIVMTAGNWAYLYGEGDVKYQNIELQSELIE
                     MNMDSSIVFAKFGLDSIGQEFGYPLFKEGDQQYESKTMRYNFGTKKGYITDVITQQGE
                     GYVTAGRTKKMEGDILNMVGGKYTTCDEHEHPHFYIQMTKAKVRPKKNIVTGPVYLVL
                     EDVPLYPIGLPFCFFPFSSTYSSGIIMPTFGDESTRGFFLRDGGYYFALSDYMDLALL
                     GEIYTKGSWGLSAKSAYRKRYKFSGSFNASYLVTKLGDKGLPDYSLSKDFKVNWTHTQ
                     DPKANPYLSFSASVNFSTSSYDRNNQNSLYPNANGYADVNQNTKSSSINVTKRFPNNP
                     FTISGTMSINQTTRDSSIAVTLPSMTVTMSRIFPFKRKHPVGKERWYEKISMSYSGTF
                     SNSITTKENLLFKSNLIKDWQNAMQHSIPVSATFSVLKYLNISPSFNYKERWYTSKIE
                     QEYDTQKQALVARDTTYGFYRIYDFNASISASTTLYGFYKPLPFLGNKVEMIRHRFEP
                     SITVSAQPDFASSRFGFYQTYVYQDANGEDREYTYSPFAHNMYGVPGTGKQGNISFDV
                     NNNIEMKVRSDKDSTGFKKISLIDKLSLGMSYNMAADSFKWSDLSVGLRLKLSKSYTL
                     NLNGQFDTYTYDENGHRVDIPRWKAGKGIGRLRGTSTSFSYTFNNDTFKKLFGGGDSS
                     SDKSGNQSASTDPNADPDGLNPDGEGEGENKESGGRLLGKKKETGETDADGYLISKIP
                     WSLSFSYGLSLRYGDFNRSKLEYDYALTHSLSFNGNIQPTKNWRFNFNATYDFDAKKI
                     SYMTCNVTRNLHCWQMTASFVPVGPYKSYTFSIAVSSALLKDLKYDKRSNYRDGQQWY
                     "
     gene            complement(32352..32894)
                     /locus_tag="ACZPB4_00170"
     CDS             complement(32352..32894)
                     /locus_tag="ACZPB4_00170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing metalloprotein"
                     /protein_id="HIR1096681.1"
                     /translation="MKPLDIIKKYYPESSDAYRILVTHSRSVADKALALARLHPEMNL
                     DLTFIEEATMLHDIGIFLCNAPDIDCHGEADYICHGYLGADLMRKEGYPRHALVCERH
                     TGTGLSLAMIEERNLPVPHRDMRPVSLEEQLICFADKFFSKTKLTKEKPADKIKQSLS
                     KYGNETVEQFEHWCKLFLGE"
     gene            complement(32954..35368)
                     /locus_tag="ACZPB4_00175"
     CDS             complement(32954..35368)
                     /locus_tag="ACZPB4_00175"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HIR1096682.1"
                     /translation="MNVKTLFYAVAFLSLSWVPFTYAQDVLPEYTQARRFAPSNAEQL
                     LFSYTLTPNYFNNSDKFWYEYKTSEGTNWYLVDPDSRNKRLLFDRDELAAQISEIVRE
                     PFTGQQLPIEDLRLKENDRTFTFSIKGTNGNYFFSYDYPSSRLTRITKDEIPAKIRWA
                     NISPDKKRVVFAKDLNLYVMSYEDYEKAVKDPEDKTISEIALTTDGEKDFGFGMPRTF
                     LNTDTLCDHKRKYVMGNWSPDGRYFAATLSDQRAVQDLWVINSIAKPRPTLETYKYQM
                     PGETGSPIVHLYLFDLENTGKRKEIRVDCFKDQTINLASKPDKERTGLTRNSIWLGDN
                     QTFYLTRVSRDMKRVDICSYTIGEDSVKAIIEERLNTSMETRPLAMTDNGKELIHWSE
                     RDGWAHLYLYDAQGNLKNRITKGPWHVDAIVDVDSKNRVVYFKANAREKGDTTPYYEH
                     LYRVNLDGSGLKLITPGDYFHLVSMDKSMRYIVDNYSRVNTIPATALYDNQGNRLMTL
                     EESDFSQLFMAGYKFPEPFSVKAADGVTDLYGVMYKPFDFDSTKVYPVINYVYPGPQQ
                     EGTFFRYIPLNPRTDRLAQAGFVVVCMGHRGGHPSRSKWYHNYGYGNLRDYPMADHKV
                     AIEQLCARYKFMDINRVGIHGHSGGGFMSTAAMLLYPDFFKVAVSCAGNHDNNIYNRW
                     WGEKHHGVKEITDDMGNISFDIRIPTNQELARNLKGHLLLIHGDIDNNVHPANTIVVV
                     DELIKAGKRFDMLIVPGKRHHFDDYNEYYYWRMVDYFSEYLRGERETGADIKDLKLGN
                     WFQGYQ"
     gene            35566..36699
                     /locus_tag="ACZPB4_00180"
     CDS             35566..36699
                     /locus_tag="ACZPB4_00180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012056145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HIR1096683.1"
                     /translation="MENKPFIFGVATSGDNFTDRKKETERLLLNFQHGVNTVLISPRR
                     WGKTSLVQKACHLAQSDKLKVVYLDIFSCRSDRDFYDAFAAAILKQTSSKLDEWLENT
                     KLFLSRISPKISIGTDPMTDFSISLEMNPQSNDVDEILQLPEKIAQKKGYNIVVCIDE
                     FQQIAEFKDSKTFQKRLRSVWQLQKSVSYCLFGSKKHLMNELFEKKSLPFYKFGDAIY
                     LPKIGTSDWINYICGRFEATGKQISKELAEKICQRVDNHSSYVQQLAWLVWIHTDKVA
                     TEQNFEEAYQDIIDQNTPLFEKQTESLTTYQMNFLRAILDGVHSEFTTQEILQKYKLG
                     SSANVSIVKRALVKKELIEIEKRKVIIPDPVMKVWLKKELGGV"
     gene            37084..37518
                     /locus_tag="ACZPB4_00185"
     CDS             37084..37518
                     /locus_tag="ACZPB4_00185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008782035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HI0074 family nucleotidyltransferase
                     substrate-binding subunit"
                     /protein_id="HIR1096684.1"
                     /translation="MSRDIRWLQRFDNFSKACARLLTITDTMEYDALSELEKEGLIQR
                     FEYTFELAWKVLQDYMQYLGFQFQTGPNTTLQLAFENGLIKDHDRWRKMAKARILTSH
                     TYNEGEADEIAKGIYADYAPLLRELRDLLIIRKNETENKDLF"
     gene            37528..37827
                     /locus_tag="ACZPB4_00190"
     CDS             37528..37827
                     /locus_tag="ACZPB4_00190"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HIR1096685.1"
                     /translation="MFGLSDNVVEELREVFRKYGNIRRVLIFGSRAKGTSHAGSDIDL
                     AMDGEDITFGQQLDINNRIDDLGLLYKVDLLNYQKQKGTPIGEHIDRVGKIFYSR"
     gene            37898..39091
                     /locus_tag="ACZPB4_00195"
     CDS             37898..39091
                     /locus_tag="ACZPB4_00195"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033922 - peptidoglycan
                     beta-N-acetylmuramidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exo-beta-N-acetylmuramidase NamZ family protein"
                     /protein_id="HIR1096686.1"
                     /translation="MKQIFIFLVILFSLTPTVYSQNAPLKLGAERMDVVTRLLKDKRV
                     GLVVNQTSILEKRQIHLLDALVAEGIDVKKVFAPEHGFRGTGDAGEEIKDSRDLKTGI
                     PIISIYGKNKKPSAEQLGNLDVIVFDIQDVGARFYTYISTMHYVMEACAENNKEFIVL
                     DRPNPNDFVDGPIRQKGFESFVGVDPLPILHGLTVGELAWMINKEGWLKSTPDTCRLK
                     IVKMENWKHGDPYWLPVKPSPNLPNDQSIRLYPSLCFFEATNISVGRGTYYPFQVLGF
                     PDPKYGNFTFTPTSLPGFDTNPLQKDKVCYGIDLREYPFEGGLTLRFFLDFYNKAGKD
                     QAFFFSRPNWFDLLAGTKQLRYQIVRGLSEKEIRESWKPELDQYKAMRKKYLLYPDYP
                     TQNKK"
     gene            39098..41155
                     /locus_tag="ACZPB4_00200"
     CDS             39098..41155
                     /locus_tag="ACZPB4_00200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012056141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor plug domain-containing
                     protein"
                     /protein_id="HIR1096687.1"
                     /translation="MNYWESHTQVAVRFRRFDRKRYAAFRSMHKVINIGVVTASTLLF
                     ALPDTAQAQKTIEPNRTGEEASVELEEVEVTASRAPIARNQATKIVTVIPARDIAAAP
                     VTSIQDLLEYAAGIDVRQRGEGGTQADISIRGGTFDQIAVLLNGVNLSNPQTGHYSFD
                     LPVNLSDIERIEVVSGPSSRIFGASAFAGAINIITKTGKENRISTDNYAGMHKLWKLE
                     AAINHATTHFGQRLSAGYTSSGGYIDNTDFKQLNLFWQSELKSEEADFQFQAGYNDKG
                     YGANSFYSASYPNQYDKTRRFFLSAGGEIHGKIKFTPKVYWTRHFDRYELFRSDPADW
                     YTGHNYHETEVFGANLNATTQWKLGRTSMGVEFRNEGVKSNVLGKPMKEPQDVPFEKE
                     GQYLKSDNRSNISYFLEHNVLLRRFTLSVGVLANYNSALNEGIHFYPGIDASYRIGDN
                     FRLYGSWNRALRMPTFTDLYYEGKTNKGNPDLKPEESEAFEVGLKYNTYFLRAHIAGF
                     YRKGKNMIDWVKEKPEDIWESQNLTKVDNLGFETNLSLLPRELGNKRFFIRKIELGYA
                     FIHQDKDSEGYISNYALDYLKHKFTAQLSHSIWKGFSATWYVRWQDRAGSYTKYENLK
                     PAYEEPYAPYCLVDMKVNWEYQRLNLYAELNNLLNSTYYDLGNIPQPGIWFKAGFRYS
                     FKY"
     gene            complement(41205..41654)
                     /locus_tag="ACZPB4_00205"
     CDS             complement(41205..41654)
                     /locus_tag="ACZPB4_00205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="META domain-containing protein"
                     /protein_id="HIR1096688.1"
                     /translation="MRKGLFYICLLLVGVGLFAGCKSKKAVVASFSDLDGEWGVVEMN
                     GKTLNPEETHQVLVFDVARQGLSGNAGCNRLMGKIEYNDAYKNIIKFPQVATTRMACP
                     DMSGERELLEALNKVVRFEAQGEAAPVTEIALFGTNNDKLLVIKKQK"
     gene            complement(41654..42079)
                     /locus_tag="ACZPB4_00210"
     CDS             complement(41654..42079)
                     /locus_tag="ACZPB4_00210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="META domain-containing protein"
                     /protein_id="HIR1096689.1"
                     /translation="MKKVLFYAFLLPAFVGMMFSCSDVKTDVKKLEGKWNVVEVKGEK
                     VLEEGLPQMDFNMAEKKLHGNTGCNLFNTTITLDPEDVSSITIAPGATTMMACPNMDL
                     ETSVLQSMDQVRSVKAGKDENEMLLVDQDGNVLLVLERN"
     gene            complement(42163..43533)
                     /locus_tag="ACZPB4_00215"
     CDS             complement(42163..43533)
                     /locus_tag="ACZPB4_00215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HIR1096690.1"
                     /translation="MYRLFRAPRGLRGKLFKLTGPIFLETLLMLTLGVVDTLMLSHHS
                     DNAVAAVGVVNQLLNMVFLLFNITTTGTSVMCALYFGAKDHKSFIQVLGTSLLFNAGI
                     GCLISLMLFLFGKEMLVLMDIRPDLMPDAETYMHIVGGFGFFQAVSFTISAVLRAANK
                     PNYAMQVTLLINVLNVFGNYALIFGHFGFPALGVQGAAISTSVCRGVAMTLLFIMLFK
                     RLVPRIPLAYFRPFPFQKLKDVLKIGLPSAAEQISYDASQVTIVYFINMLGNEYLTAR
                     VYVMNIVIIGYIFSLSIAQATSICTGNLVGARKKQAAYLLSWYAWRRSLLITLVASTG
                     VYLLGRPLLGIFTENQAIITIAMGALLVDVLLEQGRATVLLFLFCLRSVGDVVVPVII
                     ELFCMWFFAVFCGYMFGIVFGLGLAGMWFAFALDECSRGAVLCLRWRTQKWKKRMLIK
                     NPVNIS"
     gene            43679..44977
                     /locus_tag="ACZPB4_00220"
     CDS             43679..44977
                     /locus_tag="ACZPB4_00220"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009016983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M23 family metallopeptidase"
                     /protein_id="HIR1096691.1"
                     /translation="MDKKLPICIVLVMLMSCFSCKQPQQPTEDADMDTQWVDSSQHLY
                     QYGICIDSLDVKEYLMKNGDNPASIFSGLGFTALKADSISRASTHVLDPTKLRAGMHY
                     YTFSTVDSLETIRYIAFAKSLTDYAVIDLTGDTINAYEFNKPITLKKKYTEGVLNSSL
                     WNVIKANGGDPYLAIKISDVYAWQIDFFDIKDGDSFKVLYNEAYIDDTTALSIASIEG
                     AIFTHQGKEFVAIPFTQDSIFEYFDEEGNSLRKAFLKAPLDFFRITSRFTNARFHPIL
                     KRYRAHHGVDYAAPTGTPVRSIGAGTVIAKGYQNGGGNFLKVKHNSVYTTTYMHLSRF
                     AKGIQVGSHVQQGQEIAYVGSTGLSTGPHLDFRVHKNGQPIDPLKMEAPPSEPVKPAY
                     RDSFAFVKRQILAEIDSFHVATVSKASVIYEKDSINHLNN"
     gene            44981..45349
                     /locus_tag="ACZPB4_00225"
     CDS             44981..45349
                     /locus_tag="ACZPB4_00225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HIR1096692.1"
                     /translation="MKFLGNIIWLLFGGIITSVEYLISSLILMITIIGIPFGLQTLKL
                     AILALWPFGSRVVDEGNSGGCLSLIMNVIWIFVGGFWICLTHLGFGLLLCITIIGIPF
                     GMQHFKMAALALAPFGKSIQ"
     gene            complement(45661..46491)
                     /gene="murI"
                     /locus_tag="ACZPB4_00230"
     CDS             complement(45661..46491)
                     /gene="murI"
                     /locus_tag="ACZPB4_00230"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008881 - glutamate racemase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HIR1096693.1"
                     /translation="MFPQTPGPIGLFDSGYGGLTIFDKIHQLMPGYDYVYLGDNARSP
                     YGTRSFEVVYQFTRQAVLRLFESGCQLVILACNTASAKALRTIQQKDLPTWDPNRRVL
                     GVIRPTVELVDTISRTKHIGIVGTSGTITSNSYTIEIGRMYPHIQVTGEACPMWVPLV
                     ENNEFNSPGADYFVKKHIDHILSVDPQIDTLILGCTHYPLLMDKIRAFLPSGITLFSQ
                     GEHVAESLRDYLGRHPEMDRKLTKGGSCRFLTTESAEKFSEAASIFMNTPVSVSQIEL
                     "
     gene            complement(46582..47076)
                     /locus_tag="ACZPB4_00235"
     CDS             complement(46582..47076)
                     /locus_tag="ACZPB4_00235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OmpH/Skp family outer membrane protein"
                     /protein_id="HIR1096694.1"
                     /translation="MKKLIVLLLMILPLGAIAQEVKIAFVKTQEVFMAMPEVSGMEKQ
                     MADLNEKYRVELKQMQDEYQKKYSDFVAQQDSLTENIKLRRMQEIQDIQERMDNFVQV
                     AQQDVQKKQQELLQPIQQKLHEAIQKVGEEKGYTYIIDPAALLYTGTNAVDATPFVRT
                     KLGL"
     gene            complement(47151..47666)
                     /locus_tag="ACZPB4_00240"
     CDS             complement(47151..47666)
                     /locus_tag="ACZPB4_00240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005637338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OmpH/Skp family outer membrane protein"
                     /protein_id="HIR1096695.1"
                     /translation="MKKIITLSCLMLLCSFAGMAQKFALIDMEYILKNIPAYEMTNEQ
                     LSQVSKKWQNEVEAIQQEAQNMYKNYQSDLVFLSAEMKTKREEEIVKKEQEAQDLKRK
                     YFGPEGELYKKRESLMKPIQDEVYNAVKEISEDKGYQIVWDRASAMSIIFASPKIDIS
                     NEVLIKLGYSK"
     gene            complement(47839..50529)
                     /gene="bamA"
                     /locus_tag="ACZPB4_00245"
     CDS             complement(47839..50529)
                     /gene="bamA"
                     /locus_tag="ACZPB4_00245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_process: GO:0071709 - membrane assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamA"
                     /protein_id="HIR1096696.1"
                     /translation="MYKRIVLFFICLGFACGAFAQEIDTTQVETPAEVPVISYSLAAK
                     KYKIADIKITGIKNYDDFVLIGFSGLSVGDEITVPGEEITTAVKRFWKHGLFSDVKIL
                     ATKIEGDQIWLEIQLKQRPRISQVNYHGIKKGEREDLEAKLGLKKGFQVTPNVMDRAK
                     IVIQKFFDGKGFKNVDVEIEQKDDPANEGEVIVDINIDKNEKTKIHRIYFEGNEKLTA
                     RELKKAMKKTNEKFSLPNDWKTSIMEMFSTKKFTTEEYENDKKNIIAKYNEHGYRDAV
                     LLSDSVANFNEKKVDIFLKVDEGEKYYLKDIRFVGNTQYSTDYLMAVLGMKPGEVYNQ
                     KKLNERLSTDEDAVSNVYFNNGYLFFNADPVEVDVANDSISLEIRIQEGPQATINRII
                     INGNDRLYEDIVRRELRTKPGMLFSREDLMRSVRELAQMGHFDPENMNPVPLPDPENG
                     TVDIEYNLVSKANDQIEFSAGWGQTGVIGKLSLKFTNFSMKNFLNPKTYKGIIPQGEG
                     QTLTLSGQTNGRYYQAYSISFMDPWFGGKRPNTLSVSAYFSKQTDISSNYLTNSGYGY
                     GYPGYGYGYPGYYGGGYGYGSNYYGNYGYNNSYEYAYDPDKSIMMFGLAAGYGKRLNW
                     PDDYFQFMATLNYQLYMMHDWDYFLVNNGNCHNINLELMLQRNSIDNPLYTRKGSQFM
                     LSVAATPPYSLFDGKDYASMSSSDPDKYKFIEYHKWKFKAKIFSPLAPLTVKRTPVLM
                     TRVEYGFLGTYNKNKKSPFETFYMGGDGMSGYSSTYAQETIGLRGYENGSIAGNGGYN
                     SYGYAYSRLAMELRYPFLLEPSSTIYGLVFVEAGNAWTDLKNFNPFNLKRSAGVGVRI
                     FLPMIGLMGLDWAYGFDEPNYGSNGKRSGSNLHFIIGQEF"
     gene            complement(50544..51287)
                     /locus_tag="ACZPB4_00250"
     CDS             complement(50544..51287)
                     /locus_tag="ACZPB4_00250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HIR1096697.1"
                     /translation="MSLIEKIDKNRLPRHVAIIMDGNGRWAKAKGKDRSFGHQEGVVS
                     VRKIMDAVTQLGLKYLTLYTFSTENWNRPEEEVQALMSLLVSAIHRETPDMMKKNVRL
                     TAIGDLSRLREDAYNTLQECIDTTSANTGTTLVLALSYSSRWEITRAARQLAQEVLEQ
                     KINPNDITEAMVSDHLTTKNIPDPDLLIRTGGEKRISNFLLWQLSYAEFFFTDVFWPD
                     FREEELYEAILYYQQRERRFGKTSEQLIL"
     gene            complement(51299..52003)
                     /gene="porG"
                     /locus_tag="ACZPB4_00255"
     CDS             complement(51299..52003)
                     /gene="porG"
                     /locus_tag="ACZPB4_00255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IX secretion system protein PorG"
                     /protein_id="HIR1096698.1"
                     /translation="MTSTFFQRLLIIILLAGTIPTLWAQEYKYEIGGMAGGAFYMGDA
                     NKNTIFKGMNPAVGAVFRYNINFRWALKANLMWGQVSGKTEGMENVFPNNAQTSFNRS
                     IMELGGQAEFNFFPYSDKFDYAGAKRFSPYVLVGIGLTVAPGGGKTFASPNIPLGVGM
                     KYKIKNRLNLGCEFSFRKLFGDGLEGKDMLDDPYGVKGSALKNKDWYSFLLLSVTWDF
                     GPRCRTCNNAKNISEY"
     gene            complement(52085..53461)
                     /locus_tag="ACZPB4_00260"
     CDS             complement(52085..53461)
                     /locus_tag="ACZPB4_00260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6242 domain-containing protein"
                     /protein_id="HIR1096699.1"
                     /translation="MKNKLVLFITGCFALVLSSCLKSDEIVGVEAIKNCQIHTFSLSH
                     DSVSGLDTVKFTIDQLTGRIFNIDSLPFGTKIEKVVCKIGFANSSVIGGVEASPEAYP
                     DSTYYLSSLSDSIDFSAPVKFVVHAYDQVTTKVYMAQVNIHQVVPDSMVWSMYANPMI
                     GITVKDQKVVTYDYNGSENYFMYVKPAESGKPYQLYYAPVSAPKGWQSLSLTGLPSDG
                     LLISQITEYNNALYVPATNGTLYRSEDGLTWSAVENAPSVKYVLGSVKQGTKQPSALA
                     TIVDQEGKLAFYAMNESMEWIAGDAVPSGFPVTGFSNLQYAAMYHEYLMTASGRTVDN
                     QVVNTTWATMDGISWALMASGDANFTKREGAMITNYDDKFFLIGGIDASNKALKDMYQ
                     SIDYGISWSLIDSMVVLPTDYAARGFSSIIVDKENFVNIFGGKTSTGSNDLNQLWRGR
                     INRLIPKE"
     gene            complement(53581..54660)
                     /gene="ribD"
                     /locus_tag="ACZPB4_00265"
     CDS             complement(53581..54660)
                     /gene="ribD"
                     /locus_tag="ACZPB4_00265"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012056136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA];
                     GO_function: GO:0008835 -
                     diaminohydroxyphosphoribosylaminopyrimidine deaminase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HIR1096700.1"
                     /translation="MIEVEEKYMARCIELAKGGRGNVSPNPMVGAVVVHKGRIIGEGF
                     HRKCGEAHAEVNAIASVKDESLLTDSTIYVSLEPCSHYGKTPPCAELIIRKGIPRVVV
                     GCLDPFPEVSGRGVRMLREAGVEVVTGVMEEEARALNKAFMTLQTKGRPYIILKWAQS
                     EDGFIDRLRMDVSEPVTVLSSPETSRLVHKLRSEVAAIMVGTRTALLDNPSLNVRHWS
                     GNSPVRVVLDRRLVIPDSYRLLNGSSRTLIFTEKEVENRENVEYIRIDFEGPVIRQVL
                     DHLAVRKLDSLLVEGGTQLINSFVEADVWDEARVETAPVRLYQGVHAPMLGKEAVSGI
                     SGRSVMSIKNHNYEILNHNDEFEKS"
     gene            54717..55673
                     /locus_tag="ACZPB4_00270"
     CDS             54717..55673
                     /locus_tag="ACZPB4_00270"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N5-glutamine methyltransferase family protein"
                     /protein_id="HIR1096701.1"
                     /translation="MTETIAYIRNSLKDIYPPGEAQALVRLIMERVCGLSTHQLLLGK
                     GKELSDTEKFKIKEIVEGLRLYKPIQYLLGIADFYGMEFKVTPDVLIPRPETAELVER
                     IITDYRGQAPRILDIGTGSGCIAISLAKHLPKAEVAAVDISPEALAVAEENARLNQVS
                     VSFLELDILSEGYPSFMQGKLKFHVEETKVSRKENKSFTYMKPKSHTEETAVSPIGNF
                     NCIVSNPPYIMNKEKATMEANVLENEPHLALFVPDDDPLLFYRAIARFGQRHLVEGGH
                     LYFEINALCGKETVAMLRQENYTEVELIQDLYGKDRIVKAKI"
     gene            55670..56170
                     /locus_tag="ACZPB4_00275"
     CDS             55670..56170
                     /locus_tag="ACZPB4_00275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory protein RecX"
                     /protein_id="HIR1096702.1"
                     /translation="MKEITEPEMLHRAAAYCSAAERCIQDVQKKIDAAGLPPDASERI
                     IARLLKERFIDESRYTRFFVNDKLRFNKWGRVKIGYELYKKNIPSPIREESLAAIDEG
                     EYRSILLDLLKSKKKSTKGKDERDLFNKLLRFAAGRGFESRITLDCLSQLFKGIDCED
                     YADDME"
     gene            56151..56840
                     /locus_tag="ACZPB4_00280"
     CDS             56151..56840
                     /locus_tag="ACZPB4_00280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030420 - establishment of competence for
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HIR1096703.1"
                     /translation="MPTTWNNLLNLFFPNLCKICKRPLVEGEEQICLKCLCDLPHTGY
                     HQQANNPVEQLFIGKNRIEYATAYLRYEKGGKVQSLIHSLKYHDNKELGYLLGRQIAR
                     ELQADHSPICTVDLLIPVPLHPRKKRQRGYNQSEWIASGIRSIWDIPIDTQSLARTTH
                     TSTQTRKAIYDRWLNVCSIFNVIHPESLKNKHILLIDDVITTGATISACAKALSGIPG
                     IRISILALSVA"
     gene            56927..57562
                     /gene="pyrE"
                     /locus_tag="ACZPB4_00285"
     CDS             56927..57562
                     /gene="pyrE"
                     /locus_tag="ACZPB4_00285"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HIR1096704.1"
                     /translation="MKTLESLVAEKLLKIKAVKLQPANPFTWASGWKSPIYNDNRKTL
                     SYPVVRSFIKLELARVISEKFENVDAIAGVATGAIAQGALVADLLGLPFVYIRSTPKD
                     HGLENLIEGELKPGSKVVIIEDLVSTGGSSLKAVQAVRNFGCDVAGMVAIFTYGFPVA
                     EAAFKDAKVTLTTLSNYDAVLEEAVRTHYIDESEIAVLQEWRKDPANWDPK"
     gene            57585..57998
                     /locus_tag="ACZPB4_00290"
     CDS             57585..57998
                     /locus_tag="ACZPB4_00290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SRPBCC family protein"
                     /protein_id="HIR1096705.1"
                     /translation="MTEEFVSEVKQIPHNDERIFTMLSDLSNLERIKDRIPQDKIKNF
                     EFDSDTCSFAVDPVGKITFQIVEREPNKLIKFTTTNSPVPLFLWIQLKQVAEDDTRLK
                     ITVRADLNPFLKPMVSKPLQEAVDKISTVIASLPY"
     gene            58012..59352
                     /gene="argH"
                     /locus_tag="ACZPB4_00295"
     CDS             58012..59352
                     /gene="argH"
                     /locus_tag="ACZPB4_00295"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004056 - argininosuccinate lyase activity
                     [Evidence IEA];
                     GO_process: GO:0042450 - L-arginine biosynthetic process
                     via ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HIR1096706.1"
                     /translation="MAQKLWEKNVQVDHEVDIFTVGKDREMDLYLAKYDVLGSMAHIT
                     MLESIGLLTKEELNVLLAELRNIYAVADRGEFIIEEGIEDVHSQVELMLTRRLGDMGK
                     KIHSGRSRNDQVLLDLKLFTRSQIQELVELVSGLFDVLISQSNRYKDVLLPGYTHLQV
                     AMPSSFGLWFGAYAESLVDDLQLMQAAYRICNRNPLGSAAGYGSSFPLNRQMTTDLLG
                     FDSLDYNVVYAQMGRGKMERTVAFAMAGIAATLSKLAFDACMFNSQNFGFIKLPDQFT
                     TGSSIMPHKKNPDVFELTRAKCNKLQGLPQQIILISNNLPSGYFRDLQIIKEVFLPAF
                     DELKDCLRMVTHMMREVKVNEHILDDDKYSLLFSVEEVNRRVLAGMPFRDAYKQVGLD
                     IEAGKFVPSKSVNHTHEGSIGNLCNEPIATMMRSVIGSFSFERMNEAEKKLIHG"
     gene            59345..59818
                     /locus_tag="ACZPB4_00300"
     CDS             59345..59818
                     /locus_tag="ACZPB4_00300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rieske (2Fe-2S) protein"
                     /protein_id="HIR1096707.1"
                     /translation="MDKIRRIFPLLILFTLLSCADTIETRIPYRVVYLELDLTYQDKA
                     LNAIQAYKIYTSKDVDQAGEQTGFGGVLVYHGLSSNGTGAFFAFDAACPHEASTNVIV
                     DVDESAVYAICPKCGSKFELLNGIGNPVEGPCAEEKQALKQYVVDTNGNKIYIHN"
     gene            59892..59964
                     /locus_tag="ACZPB4_00305"
     tRNA            59892..59964
                     /locus_tag="ACZPB4_00305"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:59925..59927,aa:Gly,seq:gcc)
     gene            59988..60072
                     /locus_tag="ACZPB4_00310"
     tRNA            59988..60072
                     /locus_tag="ACZPB4_00310"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:60022..60024,aa:Leu,seq:taa)
     gene            60088..60160
                     /locus_tag="ACZPB4_00315"
     tRNA            60088..60160
                     /locus_tag="ACZPB4_00315"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:60121..60123,aa:Gly,seq:gcc)
     gene            60253..61035
                     /locus_tag="ACZPB4_00320"
     CDS             60253..61035
                     /locus_tag="ACZPB4_00320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004305885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HipA family kinase"
                     /protein_id="HIR1096708.1"
                     /translation="MELRTANVTRYIMPLREGGSLPALAEADDEFKYVVKFRGAGHGT
                     KALIAELIGGEIARCLGFHVPELVFLNLDEAFGRSEGDEEIQDLLQASQGLNLGLHFL
                     SGALTFDPVVNRVDPKLASQVVWLDALLTNIDRTVRNTNMLIWNNELWLIDHGASLFF
                     HFSWVNWQKHAIGPFIHIKDHVLLPQATLLEEVDKDFKRILTEEKIREIVGLVPGDWL
                     HWNDSPGTPQEIRDVYIRFLIDRIAHSDTFINEVRHARQTLI"
     gene            61013..61396
                     /locus_tag="ACZPB4_00325"
     CDS             61013..61396
                     /locus_tag="ACZPB4_00325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3037 domain-containing protein"
                     /protein_id="HIR1096709.1"
                     /translation="MQDKHLYEYAVIRIVPKIEREEFINVGLIMFCKRPKFIKARYHV
                     DEKKLRLFTSDIDKESLCANLHVFDKICSGAKDGGPIASLDIPERFRWLTAIRSASIQ
                     TSRPHPGFSNDLEQTFERLFQELVL"
     gene            complement(61484..62959)
                     /gene="gltA"
                     /locus_tag="ACZPB4_00330"
     CDS             complement(61484..62959)
                     /gene="gltA"
                     /locus_tag="ACZPB4_00330"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004355 - glutamate synthase (NADPH)
                     activity [Evidence IEA];
                     GO_process: GO:0006537 - glutamate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent glutamate synthase"
                     /protein_id="HIR1096710.1"
                     /translation="MTTEELIAARRAEPWREALRKSKKNKERADIPRVKMNELDPEYR
                     SRTRLEEVNLGLTKEQAMQEAERCLDCPNPTCMQGCPVNINIPTFIKNIERGEFLEAA
                     KTLKETSALPAVCGRVCPQEKQCESKCIHLKMGKEAVAIGYLERFAADYERESGNISV
                     PEIAEKNGIKIAVVGSGPAGLSFAGDMAKRGYDVTVFEALHEIGGVLKYGIPEFRLPN
                     KIVDVEIDGLRKMGVQFEKDCIVGKTISYDDLHADGFKGVFVASGAGLPNFMNIPGEN
                     FVGVMSSNEYLTRVNLMDAANPESDTPVLQGKKVAVIGGGNTAMDSVRTARRLGAERA
                     MIVYRRSEEEMPARLEEVKHAKEEGVEFLTLHNPIEYIGDERGRVKQMRLQKMELGEP
                     DASGRRRPVPIEGAIETIDVDEVIVSVGVSPNPLIPRAFGGLEVSKKGTIVVEEDSMR
                     STLGDVYAGGDIVRGGATVILAMGDGRKAAAAMDADLKGKV"
     gene            complement(62980..63777)
                     /locus_tag="ACZPB4_00335"
     CDS             complement(62980..63777)
                     /locus_tag="ACZPB4_00335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008152648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfide/dihydroorotate dehydrogenase-like
                     FAD/NAD-binding protein"
                     /protein_id="HIR1096711.1"
                     /translation="MNKIVSKEHFSANVVKLEVEAPLIARSRKAGHFVIVKVGDKGER
                     IPLTIAGADTEKGTITLVIQAVGGSSRKICELNEGDYITDVVGPLGQATHIEKVGTVV
                     CAGGGVGVAPLLPIVEAFHKAGNRVIVVLAARTKDLVILEEQMRQNSDEVIIMTDDGS
                     YGTKGLVTNGVESVINRERVDLCVTIGPAIMMKFVSALTKKYEIPTVASLNTIMVDGT
                     GMCGACRITVGGKTKFVCVDGPEFDAHQVDFDEMIMRLGAYKDIEKK"
     gene            complement(63869..64255)
                     /locus_tag="ACZPB4_00340"
     CDS             complement(63869..64255)
                     /locus_tag="ACZPB4_00340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HIR1096712.1"
                     /translation="MQLSIDQKDIDKFLMIGDKVLIKPKNPQSQTKTGLYLPPSVQQG
                     EKIQAGYIIKTGPGYPLPSQSEEHEVWEKKKGEEVQYLPLQAREGDLAVYLQNAAYEI
                     NFNDEKFLIVPHSAILMLVRDEGLFE"
     gene            64652..67978
                     /locus_tag="ACZPB4_00345"
     CDS             64652..67978
                     /locus_tag="ACZPB4_00345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SusC/RagA family TonB-linked outer membrane
                     protein"
                     /protein_id="HIR1096713.1"
                     /translation="MKHRHAIFRSRLGLALCFMLAGGAIIPQSSVLKAETSVTQQSRK
                     ITGTITDAKGEPLLGVNVVVKGTTNGTITDLDGKYVLEVEPNAILVISYIGYVTQQTP
                     ASGNVMNITLKEDTQNLDEVVVVGYGTQQKKDITGSVAVIDTEELLASSGSSATQQLQ
                     GKAAGVNIGTSGAPGSATMVRIRGINSINDNGPLYVIDGVSTRDQDLSSINPNDIESM
                     QVLKDASSAAIYGAQAANGVILITTKKGTKTGQPRLTYDGYYGFSKTGKRYDVLNAYD
                     RIDVEWQASKNNLDLTGASANGELPYHQQFGSTSDSWVNHLPNYMTVTGAGGSTSIDP
                     SDYDQANNVVYAPVGDTNWWDEISQLGWMQNHQLSLSGGTDKGQYTMSMNYFDQQGTA
                     IESYFTRYQARANSSYNVRPWLRFGENQTYSFSKNNGLSFSGTESNIYSWTYRASPYV
                     PVYDYAGNYAGSLFAGTGNFQNPVAIRERNKDNYATTQRVFGNVYGEADLWTGLTFKT
                     NFGIDYRNDYSYSMTKNNPEFSESGSQNNFYESNYFNYRWVWTNTLSFSRTFNEIHSL
                     NILLGTEAIRDGLGRSLNARRYNYLFEDNTNTYTLDMGENNSQRTNSSTYNGEFALFG
                     MFARADYGYKDKYLLTGIIRRDGVSRFSESNRYGVFPSISAGWRMSEEAFMEPSRDWL
                     DDLKIRAGYGVTGNSEIPVATNFANLFTTSTSYTNYDMTGANNSETTGFRLSTYGNTD
                     TKWEMTKMVNLGLDATFLNGKFSGSFEWYTKKTSNMLIQAAYTSMAGESGSPYINFGD
                     IKNTGFDFMFNYRDRKGDWAWDLSLNLSHYKNEVLKLAEADDYSLWASGTRIEGYVTR
                     TTKGHAVSEFWGLKQNGFYESVADVMATKPFGQSDITEADAAAYVGRFRFEDLNGDGK
                     LDDSDRTFIGSPHPDLTGGLNATLTWKNWDFTMFWNFSIGNDLYNNTKYFTDFWTFNG
                     NKSSRLRDQSWTLNGDNSNAILPMLNTEDNYSGAYSSSYYVEDASFLRLKNLVLGYSL
                     PKELLKKAGIQNLRLYLQAENILTITGYTGLDPEFTNAYLRQSDSDTDGAGRVDLKRG
                     VDMGGWPTTMRFLLGVNFTF"
     gene            68005..69753
                     /locus_tag="ACZPB4_00350"
     CDS             68005..69753
                     /locus_tag="ACZPB4_00350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0019867 - outer membrane [Evidence IEA];
                     GO_function: GO:2001070 - starch binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RagB/SusD family nutrient uptake outer membrane
                     protein"
                     /protein_id="HIR1096714.1"
                     /translation="MRHKILIVSAAALFTLSSCGEDFLYKAPQGSIDQEALTNAEGVE
                     LLVVNAYAGLTRPTGYDNMFNWVFGGVYGGDANKGSESNDQSVLNSVETYAVTATNDY
                     LLNKWKDAYYGAQRCNLALNVMKEAADMDETTKANRTAELKFLRALFMFEGVKIFGPT
                     GMPYIDETIAAEENDPKVHNGTDIYPNILADVEAAIEGLPEKQTEVARPTKTAAKALK
                     AKILMQQGDMAAAKPILADIIANGLSPKGERLALQDDLDANFNATTENGKESIFEVQF
                     SVGANNNGNYGFLLNYPHNTGPGGCCGFYQPSYELVNSFQVDENGLPYLEGEYRNKKS
                     VTERVTDYDYISKNDKTIAVDPRLDFAVGRMEIPYKDWGLPANDWVRNVSSGGVFLPK
                     KHVYSKAEQDAGLAGSTYSSGWAPGSAMNLQYLCLRDCKLLYAECLANDGELSAAMQQ
                     VNDIRERAAKPDNIIYLEDGTPAANYLVKPYPSSHAAFSNKETCIKAIHMERKLELAM
                     EGQRFFDLVRWGGDYMNKELTAYINYEKQYLTKFYGVSAPIASKTIFPIPETEIQTAG
                     NDENGQAYLVQNDAWK"
     gene            complement(69832..70425)
                     /locus_tag="ACZPB4_00355"
     CDS             complement(69832..70425)
                     /locus_tag="ACZPB4_00355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4251 domain-containing protein"
                     /protein_id="HIR1096715.1"
                     /translation="MKKIVLLLAVLLFGAGSMMAQQDKSAEKAAKQAEKEAKKAEKAA
                     KKAAEEAEANALFEQAVQALKNKDFVLEADRIEFKRGSFVYVTPNTNFVSVKGEKATI
                     QLAFNTPAAGPNGIGGITVDGTTSGVQMKTDKKGNVMYEMNVQGVAVSARVTFRMAKG
                     TNKCTATVSPNFNSNRISFTGNLYPSSESNVFKGRSI"
     gene            complement(70510..71856)
                     /locus_tag="ACZPB4_00360"
     CDS             complement(70510..71856)
                     /locus_tag="ACZPB4_00360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009016973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HIR1096716.1"
                     /translation="MSNEITWRLENENIGRLLVHYAIPAVIGTMVNALYNIVDRIFIG
                     QGVGALAISGLTLTFPILLFMQAFGMLIGAGAATRVSIHLGRKANDLADNVLGNAFTL
                     TFIIGALTIIPSMIFLDDLLMWFGGSEQTIPYAKDYLYIAIPGNLLATLSFSFNAVMR
                     ASGYPKKAMFTMMIGAVLNVILDPIFIFWLDMGIQGAAIATVISMAAGAAFVMSHFIS
                     KDSIVRFHTKYFRLKGPIIWNIFTIGMSPFSMQLAGSVVVVIMNHALKENGGDLAIGA
                     SGIISSIAMLLVMLIIGIAQGMQPIVGFNHGAGHHDRVLATLRLSIIVSTLITGVGCI
                     VSLLFPRLIVSVFSTDAELVSITDNGLRLTMLVFFVVGSQITISQFFQSIGVAWKAMF
                     LSLSRQVLFLIPAILLFPPIWGLDGVWLAQPFSDFIAAVTAWGFLWYHVKNVKNKG"
     gene            complement(71864..72874)
                     /locus_tag="ACZPB4_00365"
     CDS             complement(71864..72874)
                     /locus_tag="ACZPB4_00365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1096717.1"
                     /translation="MERIPVIKTSDLSIGYILKGGQKKRVHDALDLNLYPGEVTCLLG
                     LNGAGKSTLLRTLCGFQPPLGGEIELMGKPLNSYSQGNFSRLVGVVLTEKTNAGGITV
                     YELVSLGRHPYTGFFGQLRQEDRRIIEESLAAAGIAHKAYNYVSELSDGERQKAMIAK
                     ALAQQCPIILLDEPTAFLDVTSRIETMVLLHTLAVEQQKAILLSTHDLDLAIQLGDCL
                     WLQEKKRPMACGTPEDLIMGGAFETFFSKEGIVFDPNTGKLNTAAPTKLIGVAGDFMT
                     SYWVGNALIRNGFKPSSVSEDYISVYCNAPDSLRIQFPAEEGTRIVGSVSEMISIIIH
                     KS"
     gene            complement(72880..73914)
                     /locus_tag="ACZPB4_00370"
     CDS             complement(72880..73914)
                     /locus_tag="ACZPB4_00370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HIR1096718.1"
                     /translation="MNKQALLFYPLLGVVLLGLFVGGLAYGAVPIPLDHVMDILLGKG
                     SDKIAWQNIVLQSRLPQAITALLAGASLATSGLLLQTLFRNPLAGPSILGISDGANLG
                     VAAIMLYFGGTLGQFTDWPISGYMAVILAAFVGACVILGLIIYFSAKVKNNVMLLIIG
                     IMIGYLASSVISILNYYSSTDRVHAFVMWGLGNFSGVSLEQLPFFGTCALIGLLLAIL
                     LIKPLNALLLGEMYAANLGIRIKRTRIAILLCTGVLTATTTAFCGPISFVGLAVPHIA
                     RLMLGSSNHKMLVPVTMLTGSCVALLCNMLMVVPGSNTILPLNAVTPMLGAPVIIYVI
                     VNRKNIQYFN"
     gene            complement(74025..75617)
                     /locus_tag="ACZPB4_00375"
     CDS             complement(74025..75617)
                     /locus_tag="ACZPB4_00375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RagB/SusD family nutrient uptake outer membrane
                     protein"
                     /protein_id="HIR1096719.1"
                     /translation="MKRKTILSFITGLFLLGGLSSCMDLDETVYDKLPADDFGQSTAE
                     LNALIGNSHNTMKKFWTEYMHLSECSGSMAVTPTRRGGDWYDGGQYREIYMHTWTSQT
                     SRVKSAWKAATEAIGTCNEAIRKLQNSEILTEEEKAQDVADLRGVRAFWIYVMMDYWG
                     NIPLLTEFHPTDKVFPGNSSRQEVFDWLIQEVEEIKDICPPATTENYGSFTQGAAYSL
                     LAKLYLNAEAWGVTFSGNAYQKVIDNCDKVMAMGYILEPNWKDNFSVTNENSKEAILA
                     ATFSSSDTGNDGNVKNELHNNTLHYKDYLFLGITASGTWNGICAQPEYVRLFDEEDAR
                     LDGTFLTGLMIDKSTGKPIMTDHNNELNHTIDVNMIPGMEYDGTNWSAVEQHDGARCF
                     KWEFASDLTSSMGNDFHIFRLADIYLMKAEALLRGGGSVSEATALVNTIRERGYGNSD
                     HNYATVTLKEVQLERRLELAWEVYSRQDDIRFGCFTTGMWPQSNCERKADDYLKLLPV
                     SQDAWQVNPNLKQNPGYAAFSK"
     gene            complement(75637..78615)
                     /locus_tag="ACZPB4_00380"
     CDS             complement(75637..78615)
                     /locus_tag="ACZPB4_00380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SusC/RagA family TonB-linked outer membrane
                     protein"
                     /protein_id="HIR1096720.1"
                     /translation="MQRKKIFDSFKHWNVAILSVLMSFCMTAAFAQSGAVKGKVLDEL
                     GEPIIGANIVEKGTTNGTITDIDGNYTLSVNDLKKAILQVSFIGYNSVEEAVKGRSAV
                     DVKLGASVVNLGEVVAIGYGTQTRREITGSVANISEENFNKGVNRDASDLLQGKVAGL
                     TITSGSGDVTRSSQIQLRGTSTLQNDQGPMIVIDGVPGGDMSTVSPSDIESISVLKDA
                     SSAAIYGSRAAGGVILITTKRGSGSRTQINYDGYLTASTIANKPDMLNASEWRAANKA
                     LGKDISTYDKYNSDTDWFDEMTRVGVSQQHALSLSGGSSKSNYRASYTFLDRNGVARD
                     NYMTRHSFRFQFQQRAINDRLRIGLTGAATLTDMQMPFSDDYILAYNMLPVYPVYNAD
                     GSYFTDANHNYDQGNPVQNQDQNYKKAANNYFYGQGDVQFSILDGLTTKVNLYKSRFS
                     SDYSEWQDPRNSRGQGDTGKAIRRNRLWDRNLLEWTANYTKAFGSAEEHKVDAIVGYS
                     WENNLYADQKSEATNFAVGSMGADNIQSGNLLKIGNVTSSRNEYKLISLFARAHYSFK
                     ERYMITATVRRDGSSKFGANHKWGTFPSVSAAWGISQESFMKDTKWINDLKLRAGYGI
                     TGNQDGLRPYKSLDLYSASGTYYNNGSWPTAFRPSQNANPNLKWEQTAMLNIGLDFTL
                     FNSRLSGTIEWYDKRTKDMLYNYEVSTPTYVYNQIQANVGDMKNTGVEILLNLDVIRN
                     KDFTWTTSLNLAHNKNEITKLSNELFSTGRVYVGDPWIRGASGVTSHVVEEGRPVGQF
                     FMLKCNGLDENGKFIIEDINGDGQITDDDRTYVGDAQPDLTYGWNNTFNWKNWDASFF
                     FRGTIGNKVLNNPLAAYGNNTYIDGTNVMDNDNLLTLSENSRVCSYYVENASFLRLDN
                     LSIGYTFNTKKIDWLDKARLYVAGQNLFVITGYKGLDPEVENFRGEASDDNAGLSPGI
                     EPRNYMPKARSFTFGVNLTF"
     gene            complement(79281..81281)
                     /locus_tag="ACZPB4_00385"
     CDS             complement(79281..81281)
                     /locus_tag="ACZPB4_00385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-1,6-bisphosphatase"
                     /protein_id="HIR1096721.1"
                     /translation="MTKDIIAESVQNDLRYLQLLARSFPTIADASTEIINLEAILNLP
                     KGTEHFLSDLHGEDQAFSHVLRNASGAVKRKVNEIFSNTLRESEKKELCSLIYYPEDK
                     LELIKSQEQDLEDWYQVTLNQLVRVCRNVSSKYTRSKVRKALPKEFSYIIQELLHESS
                     VEPNKSAYVDQIICTIISTGRADDFIIAMCNLIQRLTIDLLHIIGDIYDRGPGAHLIM
                     DILCDYHNFDVQWGNHDILWMGAASGNLVSIANVIRMCLRFGNMATLEDGYGINLLPL
                     ATFAMEAYGDDPCALFMPKTKFADNAMDEKTTRLIAQMHKAITIIQFKLEGEIIRRRP
                     EFEMDDRMLLHHIDLKRGVVHIDGKDYTLKDTNWPTLDPKDPYRLSIEEEDLIRKILH
                     SFESSEKMKKHMRCFFRHGGMYQVCNSNLLFHASIPMNPDGTFKSVRILGQDYKGRAL
                     LDRVDQLIRTAYFKTGEQEEVEYAHDYIWYLWGGKDSPLFDKSKMATFERAFIEEAET
                     HKEEKGAYYTLREQEEICDKILDEFGVTGMHRHIINGHVPVRSNQGENPIKANGKMLV
                     IDGGFSRPYHLETGIAGYTLVYHSRGFQLVQHEPFESRAKAIEEGLDIKSTTIVVELS
                     SHRQMVKDTDKGADLQSQIKDLEKLLYAYRNGLIKEKERMER"
     gene            complement(81320..82831)
                     /locus_tag="ACZPB4_00390"
     CDS             complement(81320..82831)
                     /locus_tag="ACZPB4_00390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012056128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolB family protein"
                     /protein_id="HIR1096722.1"
                     /translation="MMDNTRKRKIVRNFVIGYLLLQVLVIVLYLGFWAVHPGGFVVAE
                     NERMSPPPMFPDYQGVTIPYNIAPLNFRIDVPAEKCYAKIEGSEQGVFEYYGTNTICF
                     KSKDWERLTRANKGKAFFVTITTKEGDEWTKWAPFSVYISDQAIDSHLVYRLIEPGYE
                     KWHIVGIYQRNLESFDEQPIIRNDMTGYNCMNCHSFCMGDPGQMMFHMRAANGGTYIV
                     QDKKISKLNTKTNGTISNMTYPFWHPSGRYITTSVNDIKQFFHSVKEKKMEVFDLESD
                     VVVYDVKNKEILSKASLITKDAFETFPAFSPDGKWLYFCTAPAQKMPENYDKVRYNLC
                     RVAFDPDRGEISFPIDTLVHADSLSYTFPRISPDGRFLMYTETAYGQFPIWHPDAEIR
                     MMDLENRTAMDMSALNSPDTDSYHSWSSNSDWVVFSSRRDNGLYTLPYICHIGKDGKP
                     SKPFLLPQEDPDKYDYQLYSYNIPELTKGAVEVSPYEIQQVAEKNKPEQVRFK"
     gene            complement(82834..84588)
                     /locus_tag="ACZPB4_00395"
     CDS             complement(82834..84588)
                     /locus_tag="ACZPB4_00395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6057 family protein"
                     /protein_id="HIR1096723.1"
                     /translation="MKNRLFVNNNTIILFLFIIGSILFIELNFRYWYRFLEQYMMFQT
                     TGSYFQDRLAEPGGLNEYVTEFLSLAFIHPYGASVVIALLLGLISGCFFLYLKACGVR
                     ASMLAAILPSFLIWIYPQESIALLTMLAFVQVLAYLYTSIKIDWLRYLFGFLFLGGSY
                     FFAAPANLLLALLIAVYECCAKEDKARFGVAIIAIAWGGLLPLIAMRTVYILPMREAF
                     FSKHLCHPEYPIPNSLGYIGLSYPLIVLILYYVRNRVFIRKESWKRIVSYAFLLIAMT
                     YGILYKKDPMEQAYRYDYYARQGEWQEIVSHARAHSVRDMDALIYLNLALSHTGRFSG
                     DLMRFPQIGVEGFIPHDPKSRMGLIEASEVAWQVGQVNAAQRFAFVGVLSSQRCVQPR
                     LMKRLVETYLVTGEYRAAEKYIKILESTPHYRDWAKAQRPLLDSVVCASTDWIKAKRA
                     VLPVTDNPLDLTLTFPNALAFLIDDHADNRPAFEYGMGYLLVYKDLMTFMHYMELMKE
                     RGESFPVLYQEAICLFFAAVQKDPEAFKSYPISSEVQNRFLQFMKVARGMPPAALKAQ
                     FGDTYYYYAQFTPTPKRQ"
     gene            complement(84713..87187)
                     /locus_tag="ACZPB4_00400"
     CDS             complement(84713..87187)
                     /locus_tag="ACZPB4_00400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor domain-containing
                     protein"
                     /protein_id="HIR1096724.1"
                     /translation="MKEKLFALFWVLFFALPLYAQADKTGSYSIKGQVLDSLSNESVP
                     YATLRIALAKTPDKPVKLLACDVDGKFQAPLSSAGKYIISMQSIGKAPAEKTFTISDK
                     QRNLDLGKLYMQEDNQRLGEVTVTAQKPLVKAEIDKLTYSLEDDPEAQTNNTLEMLRK
                     VPMVTVDGDDQIQLKGSTNFKIYMNGKPSNLLSNNPAEVLKSMPANSVKNIEVITDPG
                     AKYDAEGIGGIINIITTKNALQGYTGTVRVNGSSLGRVGGGGYISLKAGKFGLTANYN
                     YNYNREPWNESTSIREDLENDEQHFLTQNGRRKNNGPFQFGSLEGSYEIDSLNLLTVG
                     ANLFHGKMTNRSEYTVNMQDINRNPVYDYNRNSDATETFGSTDVSVDYQHSTHKKDEL
                     LTISYRFSHSPNDNKDYTELKNVVNYNPWLGYPQNNINKASTNEHTGQVDYTTPTWKD
                     QTLEVGAKYIFRQSRSNTDRTAFNDSLNIWEDITSKDSHFRHTQHIYSAYLGYSMKFD
                     KFGVKAGVRAEGTALDVKYEMAPDMNFDTHYFDVVPNATVSYQLSMAQQLRLGYNMRI
                     QRPGIWYLNPYVNNADPQNISFGNPNLDSEKSNNINLNYSMFAQKFSINASATYTFVN
                     NSIEQYTFIDPENPGVFQTTYGNIGKKQSTGLFVYANWNPVPLFRIYMNGGMDYTDLK
                     SEKNDMANSGFSGRIFAGTQFNFPLDFRVNIQGGYFSPWIQLQGKGSPFYFTGISVNK
                     DFLKKKLSVQLSFQNPFWKRMKMENTTSDDTFFRREINYRTMRMLMVSVSYRFGTLKD
                     AIKKVKRGISNDDMKSGGSGGGEQQM"
     gene            87434..88075
                     /locus_tag="ACZPB4_00405"
     CDS             87434..88075
                     /locus_tag="ACZPB4_00405"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SagB/ThcOx family dehydrogenase"
                     /protein_id="HIR1096725.1"
                     /translation="MRTIFCVLATLMLGLTSLQAQSLKAIKLNAPDKTRGASVMKALA
                     DRHSEREFANKKLSLQDLSDLMWAAIGINREDGKRTAASALNKQDVDVYVLMEEGAYL
                     YDPKAHQLNPVAEGDHRPLIGGKQTSVNSAPACLLMVSDVSKFGNVGTPQLRERFGAL
                     DAGLVSQNIALFCSGCGLVTVPRGSMEADALKKVLKLSDSQIPMINHPVGYAK"
     gene            complement(88129..88452)
                     /locus_tag="ACZPB4_00410"
     CDS             complement(88129..88452)
                     /locus_tag="ACZPB4_00410"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: protein motif:HMM:NF037100.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HIR1096726.1"
                     /translation="MKYGLSDIELNKLREFYARYEDIEEVILYGSQAKGNHKPFSDVD
                     ISLVGANLTRSRLNQIAFVIDDLLLPYQFDLSIFHKLTNMELVDHIRRVGISIFCKDC
                     SQPPA"
     gene            complement(88461..88895)
                     /locus_tag="ACZPB4_00415"
     CDS             complement(88461..88895)
                     /locus_tag="ACZPB4_00415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012056126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase substrate binding
                     protein"
                     /protein_id="HIR1096727.1"
                     /translation="MAQDIRWLQRFSNYCKALAKLGQAVDIVSWRLELADEIDELLQE
                     GLIQRFEYTRELVWKVMKDYAEYQGYTDIRGSRDAIRKALQIGLIEDKRWMETIEDRN
                     LTSHNYDDDVASEIYENIVLVYYPLFCRFEERMLCISENETR"
     gene            complement(88948..89136)
                     /locus_tag="ACZPB4_00420"
     CDS             complement(88948..89136)
                     /locus_tag="ACZPB4_00420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1096728.1"
                     /translation="MSTYNEMKKKAESDQNRIELRSEKVRNMIGEMPSFLIRWGNTIL
                     VVIFVLLALIAWFAFFKK"
     gene            complement(89141..91345)
                     /locus_tag="ACZPB4_00425"
     CDS             complement(89141..91345)
                     /locus_tag="ACZPB4_00425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009016960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="HIR1096729.1"
                     /translation="MSFPHIKQPDSMECGATCLRMIAKFHGKEYSAATMQNLCVVTRE
                     GVSMLGISDAAEYIGFRTICGRMTLGKMVEQRPFPCILHWNQDHFVVLYDAKKKRDGE
                     YVFYIADPGKNLLRINEDEFRNAWISTRTRGEEKGILMALQPTPAFYERKDERHTGKD
                     PFRFLWGYMRPYKCFFIQLLLGLALGSVLQLIFPFLTQAIVDKGIAGKNLNLIYLILV
                     GQLMLVLSRASVDFIRRWILLHISARVNISLLSDFLIKLMRLPMSFFDTKMTGDLLQR
                     IHDHERVERFLTAQTLTVLFSAFSFIVFGGVLLYYNRLIFGIFVLGSALYAIWVTLFL
                     KKRQLLDYTYFEQRARNQSKTMQMLNSMQEIKLQHCERRRRWEWEDIQADLFRTNIES
                     MRLQQSQEAGSILINEVKNIVITVIAATAVIGGSLSLGMMLAIQYIIGQLNAPVEQFV
                     QFLYSWQDVKISLERMSEIHDREEEETPERMIIGFNGSDRDIEIRNVTFQYEGIHSPK
                     VLERINLKIPRGKITAIVGTSGSGKTTLIKLLLGYYNPVEGDIRVGGDDLRSFSLLWW
                     RDQCGAVMQDGCLFSESIARNIAVDDGEIDKSRLLLAARIANIEEFIERLPLKYNTVI
                     GPDGQGVSQGQRQRILIARAVYKNPSYLFFDEATNSLDANNERAIVENLTDFYRGKTV
                     IIVAHRLSTVRNADQIVVLDKGRIVEVGTHDVLIDRKGAYYNLVKNQLELGN"
     gene            complement(91342..93621)
                     /locus_tag="ACZPB4_00430"
     CDS             complement(91342..93621)
                     /locus_tag="ACZPB4_00430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA];
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HIR1096730.1"
                     /translation="MRTIAFWLLFISQGLFTLSAQSYTFSGIITNEKRKMMDGVQVIL
                     SVEDSLSAMALTDEKGHFRIDGLKEGAYELRLFFLGYNAQEQILRVENRDVRKDFLLT
                     PEKTVVLDEVMVTGNRNDQVNRTATGEIFYLSEKAKNMKDPFRALQEIPRLYSDVANR
                     KVQLEDGAQPLILINGNRYNSGIATLDPREIESVEIIDVVKARYLKDGYQKILNIKLK
                     KKTQPFIFLEGATRHDVPFRKGLGVGYFEVGNSRYALYGRASVDYLYDDRSEQEQRQL
                     NTGYSKWTKGEERLDGTSYLGELQFRWMCTDKDYIVAHMYGNKKINKKKGWGDGLLTD
                     GIPQEFDYSSFNKDQSYIFTASLFHKHTFAKNHILETTLAFNKNHNENDGNRSESYLD
                     WSYLNTYLYKNDRNSGRFDVDYNVDFANGGSLNVGNQTRFTSDRIRQVSIGMPTFRHE
                     KWEEYLYADYSQSIKRFSYMLSAGLEGIWLKAGEASNHYFKPRISLSGNYDFSDHLST
                     RLGYTLTNTAPTESELNPYNMSTDSLVKTQGNPYLLPSQNHKLNLSLTFNTKGFYLTP
                     SVSYRISTDLVESYGFSEEDIYISSYRNSGKYKNLRIGGSLSYRIGNLGRIGVNAYHV
                     VDYYENQDPRKGFSCSLYFNANYKKWYLGADILYNNYTYTPISRVKYHSPSFSMVQVS
                     YNFTDYFYISVAMENCLVTYRTSMELRSGSYENYSDQRKISASFRPWILLRYTFRKNK
                     SKAMKERKNVYSIEEGIKL"
     gene            complement(93626..94924)
                     /locus_tag="ACZPB4_00435"
     CDS             complement(93626..94924)
                     /locus_tag="ACZPB4_00435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012056124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM/SPASM domain-containing protein"
                     /protein_id="HIR1096731.1"
                     /translation="MKKIYYQVVEKVLPQVYLLYNSFNNKFILLNNVRYEKYKKENIL
                     ELEQSDPVLYKSLVDNQYIVPDDFDEREIVLFRKKRMQFDASMYQVMVNTTLDCNLNC
                     WYCYENRIAGSFLKSEVIEAIKKNIEQEYIKTSYRILKLSFFGGEPFLYFRGIKEILD
                     FARNFCQVNQLDLIAEFTTNAILITESIIDYLKNFECQFQITLDGDRIHHNQIKKDKD
                     NPNQDTYEKTLRTIRLINDKIPNRWLAVRINFDNKTLEKIDEIIGDLDFLDRKYCFVI
                     LKKVWQLEKDKVNVPLLHASVQKFLDKKFLLDYYIMPKGDVCFAERHREVLFNYDGKV
                     FKCSTISSFDDQNALGEFDLQSGQVHWNETKVSYWLKEMLPQNCIDCKLLPACLGPCN
                     KQIMLHPGENICTFDAINMTLKEYLMYLFKCQLLKEELYA"
     gene            complement(95261..95407)
                     /locus_tag="ACZPB4_00440"
     CDS             complement(95261..95407)
                     /locus_tag="ACZPB4_00440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1096732.1"
                     /translation="MEIGDLLSKEELSAIKGGEWHYDEETDEWYWIEDGRKVLCPQEN
                     PRQS"
     gene            95568..96944
                     /locus_tag="ACZPB4_00445"
     CDS             95568..96944
                     /locus_tag="ACZPB4_00445"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1096733.1"
                     /translation="MKHSLYIAAIMLLVLILSQGYWLYNIYNAEKYKTQEVLEELFEE
                     AIKQEMSKRMVSNKPKDPNNPKRIIRRASDMTPEERAKLKGDTIIWPQIKNRNLKDNY
                     ADLLAQRMQDGLRNANRPLKPNVLDSLFNKTLTDHNLQAISYIEISDSTRQTVNTVGK
                     KFNLSFYKFQTEKLPIGTQGLQYVQAFVKLPLSDIVQRKLLAFIVSCLIILTSASCLY
                     YLLRTIRKAHAQLRDREIAVHSAIHDLKSPLNTAYASMDLIASLENEPMKVNILNTGK
                     TQIKQLIEIIESMLSLLKTADGKESTRKSPIDIKSFIEQTYQAIARLYPNKIPLFKLE
                     KSEDFPDMIEADTVRLERCLRNLLENALKYSNDDVRITVTLTMKNNHYRIAIKDTGWG
                     IPKKAQKKLGQQFFRVKQADKPAQPGYGLGLSSVMLMAKEMGGSLTFQSEEGVGSTFF
                     INLPAENS"
     gene            96951..97643
                     /locus_tag="ACZPB4_00450"
     CDS             96951..97643
                     /locus_tag="ACZPB4_00450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009016956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HIR1096734.1"
                     /translation="MEDKQKVIFIEDDPNLGLIIVLALQSKGYEVCYANTLSGIQDMI
                     EKDCPNILLLDLEVGNQNALDYLPFIRSKHPSLPVLIASSHNEGEEITRCYEAGANHY
                     TKKPYDIQEIDFLIQRFCKKGSPISNSISIGDYQLELSTHKLFYKQEQSKTLSPKDFK
                     LFYLLSEQLNQPVSREKLFHEIWDGQEVHDSLNNSISRLRKLLEKDTTLSIDAVKGVG
                     YILSKKDQLSSS"
     gene            97932..99026
                     /locus_tag="ACZPB4_00455"
     CDS             97932..99026
                     /locus_tag="ACZPB4_00455"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HIR1096735.1"
                     /translation="MWTFFIILPILYLAGNIYIYLKGKQALKSQSTGVKVLLSIVFWG
                     GALSFFSSFLFRNLDMPASFAQTVSQVGTGWLVFTLYMVLALLVFDILRLFHLRFKYS
                     FYLSLFLTLSLLGYGNYNYQHPDTRVINMVINKPANTDGQPLKVVAISDIHLGYATNK
                     TMLAGYVDMINAQRPDIVLIGGDLIDNSVAPLRYEHMEEELSKIYAPLGVYMVPGNHE
                     YISGIEESEKFIAQTPIVLLRDSVAILPNQIQLVGRDDRHNKGRKTLGQLTANLDKSK
                     PVILLDHQPYDLEKTEEAGVDLQFSGHTHRGQVWPMNWIVDHLFELSYGIKKIGNSTI
                     YVSSGLSLWGPPFRIGTDSEMVVFNITFKE"
     gene            99029..100207
                     /locus_tag="ACZPB4_00460"
     CDS             99029..100207
                     /locus_tag="ACZPB4_00460"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HIR1096736.1"
                     /translation="MKVFIQSIVAQLLLNPYIFWRGYQALPPKKSCRIPFILFFVLEL
                     SLYFFGFIFRNELPDNVIITIQYICNTWYIASIYITLSLLVLELIRLSQRIKPWFPKW
                     MKGHWQQTKVTLFFLIVFGVTGLMIHAYHTVMNPIVKNVYITLPKAAGDRDSLTIVMM
                     SDLHIGEVIGKDLVQKYVALSNAQHPDMVVLAGDIMDYESRFAENAHIEDDLKQLKAP
                     LGVYIIYGNHEYRANRNAKYRWLQKTGGTLLIDSVVQPDSTFYLIGRDDFIHKKRKSL
                     HSLMEGVDTGKPIIVLDHQPWSFAEMNMNGVDLGLHGHTHNGQLWPYPLLMKLVYECP
                     YGYYKKGPTQFYVSSGIGIAGPPYRVGTVSELVVLHIRFKAPKQTGERGKSTMPIQGS
                     "
     gene            complement(100278..101984)
                     /locus_tag="ACZPB4_00465"
     CDS             complement(100278..101984)
                     /locus_tag="ACZPB4_00465"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S41 family peptidase"
                     /protein_id="HIR1096737.1"
                     /translation="MYRLVQRRGIIGLFCLLFVASSVVPGWAQKDNRFEVSKNLDIFN
                     SLLKEVEMFYVDSVDVDKTVQRGIEAMLAGLDPYTEYYPEQKTEELSLMTTGEYGGIG
                     SLIRQRNNEGGVMIAEPTEGMPADLAGLKPGDLILAIDTIDVSKATNSRVSELLKGVP
                     NTKMVLTIQRPGEKKPRKFEITRKQITTPQVTYYGVKNDSIGYIYLKAFTIKSAQEVK
                     EAFLDLKKNHNIKSLVLDLRGNGGGVLEGAVQIVGMFVPKGSEVLSTKGKIKQWDRTY
                     RTSTEPLDTVMPLAILINGGTASAAEIVSGSLQDMDRAVLVGQRSFGKGLVQAPRDLP
                     YNGKVKITMSKYYIPSGRCIQQIDYSHRKEDGSVAAIPDSLTSVFYTSKKRPVRDGGG
                     VRPEFEVKEPKVPTMMYYLAADTVLFDFVTDWVQKHKTIAPIEEFTVSDEDFEALKQY
                     AKSKNFTYDRQSEKVLKNLKEVAEFEGYLEEDSTAFKELEAKLTPNLEKDFDRFKDEV
                     KRVMAAEIVKRYYYQRGELQESLKDDLVLEKALEVLGDPDLYRRTLSVPVELEAATKG
                     TE"
     gene            complement(102033..103010)
                     /locus_tag="ACZPB4_00470"
     CDS             complement(102033..103010)
                     /locus_tag="ACZPB4_00470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009016953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine kinase"
                     /protein_id="HIR1096738.1"
                     /translation="MNTIGLGNALVDVLLRLENDDVLSEIGIQKGAMDMINREQMIAI
                     RTTLAGLPRTQTPGGSVCNTMRSMSSLGANSGFIGKIGDDSIGGFYEDALEKAGVTSY
                     FIKTDGLTGSCTVMISPDGERTMGTFLGPAPTITPDEITEEMLSKYQCIYIEGYLLVN
                     EPLVRSTMEKAKKLGLKVALDLSNFNIVNAFKGMLEDIIPKYVDILFSNESEAESFTG
                     QKAAEAVHTLSELVEVSLVTLGKEGALIGSHGQFYSVPAEGGKPVDTTGAGDNFAAGF
                     LYGQSIGASLVQSARIGSMLAGYVIDVVGPEIPYDKWEQIKLKVKGILA"
BASE COUNT        30069 a        25071 c        20755 g        27163 t
ORIGIN      
        1 cgcccgactt tccaagcgta cttcctcccg atcaagggcg atatcgcttt cggcgattcc
       61 gttaccatac aaggcaaggc ggctacattt tccggcgtgt cgctacccag cggagatgtc
      121 acttggcgta ttacacgcag gcccttcctg ttgtggaggt atttccgtcc gagcgctccg
      181 acacaagttg cggaagggag taccaccctt tccggcgatg gaacattcaa cgtatctttc
      241 cgtccccaaa aagaggagga tacgaatcca tacgcttccg cataccagac ctacgaggta
      301 tcggctaccg taaccgatag caagggagag acccaagagg caaattacac cttctcggta
      361 ggagaatcca gtatcgtctt attcacgaac ctaccgccac aaatcgagaa agactcagta
      421 aaagccgtag tcgaagcccg gacaatcaat ggggagatgg tttccacctc cggtactttc
      481 aagatcgtag aactgatcgc aaaccgatcc gataagaata gcggagagag ctatcaagaa
      541 ggcaagcaag tagcttccgg tagctttacc agtggcaaag aaatcagtcc ggctattttc
      601 aacccattgc cctccgggcg ttaccgtatt ttagtagaag ccaaagatag ccaaggacgg
      661 cagagtaaga accagtccga tttcatccta tacggaaaga acgacaagcg tcctcccgta
      721 tttacccata cttggctgct gaaagagaag acaacttgtt tacccgggga ggaagcggaa
      781 atcgtattcg gcacctccga caaggacgcc tacgtactct atgaatggtt tgccggaaat
      841 aaccgcatcc atcatgagtt gattaagcta agtgacgcga accatcggtt taatatcccg
      901 ttcaagccgg aatatggaga gggaatcatc gtatccttta cgttcgtaaa agaaggtgaa
      961 ctatatatta cccaagtacc cgtagagctt cagctaccca accggcagtt gaccatcaag
     1021 ccgataacct tccgggatcg tttacttccg ggaagtaaag agagctggaa attccgtatc
     1081 accgacgcgg actccacgat cgtatccgcc gaggtactga ccagcatgta tgatgcctcg
     1141 ctagataaaa tcataccatt caattggtat ttctccccgc ggcgaacgat cctgctacaa
     1201 gctccccgtt tctcaaccgg agccggattc cagcgtagtt atcaatatga ccagacagag
     1261 gccaagtata taaaagtacc tcaatatcag tatgaccgtt taaattggtt cggtctattc
     1321 aatgagattg tcatacgagg atacggctcc agcaaccggg ctttcgccac gggtggtatc
     1381 atgctgaaat ccgcagcagc cccagtagtg gcggaatcca tgaacatcat ggaagacagc
     1441 gccgtgttag aagagcctag tgtggaatct acggaagggg aacccgtgtt cagcctatcc
     1501 gatcctttcg ccaaagagag cagcctgccg gtaagtccag agcaaacccg gcggaacttc
     1561 gcggaaaccg ccttcttcta cccgacctta caaacgaacg aggaaggaga cgtattcgta
     1621 aatttcaccc tgccggaaag taatacgact tggaaactac agctattggc caacacccaa
     1681 gacctaaaat acggtctgct tacgaaagag gtcattagca gcaaaccctt gatggttcta
     1741 ccgaatctgc ctcgtttcgt ccgccaaggg gatgaggtca gcatcagcac gcaagtcatc
     1801 aacaattcca aggaagcggt atccggccgt gtacgcatcg aactattcga tcccgctaca
     1861 gaccaaccga ttatctgctt gagcaagtca caacgtccgt ttgagttgca accggatagc
     1921 atcgctactg taagctggat gatcccagtc cccaaacaga tcaacctact gggcgtacgt
     1981 atcctagccg actctgaaaa gggaagcgac ggggagcagc agatcgtacc tgttctttcc
     2041 aatcaattgc tcatcacgga aagtaccccg ttctatttgc tcaaggaagg agagaaacaa
     2101 atccgtatct ccgggaactc ggagggagcg acaccattcc gtctcacgct ggagatgacc
     2161 gggaatccga tttggtacgc ggtacaggca ttaccgacga tcacacagcc gaacaatgat
     2221 aatatcttat cttggtttgc cgcttattac agcaatacgt tggcttccta tatcgcccaa
     2281 gcccatcccc gcatccagaa agtgatcaac caatggaccg ctcaaggagg gaatgcctct
     2341 actctctatt caaacttgga aaagaaccaa gagctgaaga acatactctt ggaggagacg
     2401 ccttgggtac tagccgccga taacgagaca gagcaaaaac aacgcttgtc tttattgttc
     2461 gacctaaacc gtgcggacgg attacgggaa gcggccttgc aacaactgat ccaacaacag
     2521 aacgaagagg gtggatggag ctggttcaaa ggtttccccg caagccgtgc gatcactctt
     2581 tctatcctga aaggtatgtc acagcttgta cagctaaacg cgatccaata tgggcaagcg
     2641 gagaaagaga tgcaaatgaa ggccctcaag ttcttggaca aaagtatgca aacggattat
     2701 gagaacttgc tgaaatacga taagaaatgg caaaacgcat ggccctcgcc ggagcaggta
     2761 gagttcttat tcgtccgcag ttcctaccgg gatatcccgg aactgggaga cgcccgggaa
     2821 gcgatccgtt tctatacgaa ccaagcggag aagcactgga atcaatattc cttaatcagt
     2881 aagggcgaaa tcgccttgtt aatgcatcga aacggtaaaa aggaggtggc gacagcgatc
     2941 ctgacatggc taaagaagac cgctacgatc tccgaggaga aaggtatgta ttgggcaaac
     3001 aaccgcaggg ggagtgatta tttcacctca ccgatcgaca cgcattgctt attaatgtcc
     3061 gtctttaacg agatcgcacc ggatacccag aatacaaacc ggatgaaaca atggttgcta
     3121 aaccagaaac gtacacaaaa ctgggaatcc gtacccgcca cggtaaacgc catttacgcc
     3181 ttgctactca cgggtagcga ttggctgaac acgcaaaaca cctgtgtagc gacatgggac
     3241 ggcaagacct atagtaccgc ggaaggggaa atcgccaccg gttacctcaa aacgatactt
     3301 ccgaacgagc cggcaaataa ttccgccaac cccgtgctct cgatccgcaa ggaaggaaac
     3361 acgccggcat ggggagctgt ttacgagcaa tacttccaag agatcgacaa ggtaaaagga
     3421 caaaaagggg tgttgagtgt cgagaagaaa ttattcgtcg agaccaataa cggtaccaac
     3481 cgccaaatcc gtcccgtaac accggagcaa ccgctccgca tcggagacaa ggtaatcgtt
     3541 cggctaacga tccggacaga ccgtgaaatg aattacgtat tcttgaaaga tctacgtgcg
     3601 ggctgcttcg aaccggccga tcaactttcc ggcccggaat caagagacgg tatctggtat
     3661 tacagatccc cgaaagacgt atccgagaat ttcttcatca atcgtctgcc ggaaggtacg
     3721 ttcgtcttgg aatatccggt ctacgtatcc cgtagcggcg aatacgccgg aggtatcagt
     3781 acgattcaat gtatgtacgc cccggaattc gtgtcgcaca ccgccggaga aagcttgcgg
     3841 atcatgccct aaacaagcct tttcttacaa tgcccgttct aacctcctta caatgcccag
     3901 tataaggagg ttagaatggg caccgtaaga aggtaagaat aggcatcgca agaagcgtta
     3961 tcttcctcta attttcagtt ttcaattctc aactttcaat tgaaatgact atctttgtaa
     4021 ttcgaattaa aactaaacga taagatgaaa caaatagttt ttattttcat ggcgatcctg
     4081 ttagcgacag gaatggcttc ggctcagaag aaagcagtta tttccgcgga aacaaccagt
     4141 ttcgacttcg gtaccatcaa ggaagcggac ggaaaagtat cccatacgtt tgaagtatcc
     4201 aatacgggcg atatgcctct ggtcattaca cgtgtaatcg cgtcttgcgg atgtacgacc
     4261 ccggaatggc cgaaagaacc ggtagctccg ggtaagaaag cccagatcaa ggttactttc
     4321 gatccggcag gacgtccggg tcctttcacg aagaccattt ccgtatacag taacgggaaa
     4381 accggaagct tcatcatgaa catccgggga gaggttgaat aagaaatacg taaaaaaccc
     4441 ccaattggaa tgctgaatat aaaaaggttg atccttgctc ttacagcaat tatatctata
     4501 acgacagctt gggcacaaca aggcgcccaa atcttgtcgg acgagttgac ttataatttc
     4561 gggacaatag ccgaggccga tggattcgcc agtcatactt tcacgataaa gaatacggga
     4621 gacgcccctt tggtcatcac ccgtgttact gcgtcatgcg gttgtacacg gccggaatgg
     4681 actaagtcgc cgatcgctcc cggtaagacc ggtgaagtta agataacgta taatccgaaa
     4741 ggacgccccg gcccgtttta taaaaccgta tcgatattca gcaatgggaa gaaagggagt
     4801 tacagcctag ccattaaggg aaatgtcacc ccgaaacctt cgcagccggt ctttacgtat
     4861 ccttattcta tcggtgatct gaagctgcat acgaagactg ttctattcag cagtatccgt
     4921 ccggaggaaa cgttgggcga gaagatcaac attaagaacg agggaaagac ctcggctacg
     4981 attcatctgg gtaaagtacc tcactacctt aacgtacagg tgaacccggc tacccttcaa
     5041 ccggacgagg tcggtgccat tacgatcctt atggatgcca aggtcttgaa gcggaaagga
     5101 cgagtctcta cgcttttgcc ggtcatggta cagagcaccg gaaagaagga agtatccgga
     5161 gagatccaga tctccgccaa cgtgatcgat aatttcagca aactatccgc tgcggataaa
     5221 gcccaagccc cgatagcgga attatccggc actttactgg aattcggcaa gctaccgaac
     5281 aagaaaagta tcgttccgtt gatcggtggt aaggtatcgg gtacgtttga gattacgaat
     5341 gccggaaaga ctccgctcac gatctacagc gtcacttgtg atgatgagcg tgtcgatttg
     5401 tccggcggca agaaagaact taaaccggga gcgaccgcta ctttcaaagt aaccttgcga
     5461 ccgaaagaga taaagacaaa acttgaagca cttattaatg tcgtatgcaa cgacccgaac
     5521 gggcctatcc gcttgatcaa ggtgacggca tacaaataat agattgatat ggaacatcca
     5581 gaaaacgatg atcagtacaa gggattgaaa gtgaataagg gcattgcgga tgtccctacc
     5641 gtaaatcctt atataaaaaa gcgtgtccaa cgcaaggtat atacgccttc cgaattcgtg
     5701 gaaggtatct taaaagggaa tatcacgata ctcagtcaag cagttacctt ggtggaaagc
     5761 tccaagcatg agcaccaaca ggtggcgcag gagattatcg agaaatgttt gcctttcgcc
     5821 gggaaatcgg ttcgtatcgg tattacgggt gttcccggag cgggaaagag tacctctatc
     5881 gactctttcg gtatgcactt gatcaaccaa gggcgtaagc ttgccgtact agcgatcgac
     5941 ccgagtagcg aacgctcgaa aggtagtatc ctaggagata agacccgtat ggaggccttg
     6001 tcgagagaga aaaacgcctt tatccgtcct tcaccatccg caggctcctt agggggagtc
     6061 gcccgtaaga cccgtgagac gatcgtatta tgcgaggccg ccggtttcga taccgtattc
     6121 gtagagaccg tgggtgtcgg acaaagcgag acggccgtac attcgatggt ggacttcttc
     6181 ctgttgattc aattggccgg taccggagat gagttgcagg gtatcaaacg aggtatcatg
     6241 gaaatggcgg acggtattat tatcaataag gcggatggag acaatatcga aaaggcgaat
     6301 ctcgccgccg ctcaattccg gaacgcctta catcttttcc caccttcgga atcgggctgg
     6361 ttcccgaaag tattgactta ttccggctat tacaacctag gtatcaaaga aatatgggat
     6421 atggtcggag agtacatgga gttcaccaaa aagaacggct acttcgatta caaacgtaac
     6481 gagcaagcta aatactggat gtacgaaagc atcaacgaca cgttgcggga taagttctat
     6541 cataacccgg cggtagaagg catgctggaa caaacggaga agcaagtctt gaacaacgag
     6601 atcagctctt tcgtggcagc caaacggatg atcgatctgt tcttggataa tatcgctacg
     6661 aaataggtat aaaaacataa gagtgtcgca cgatctgatc atgctacact cttttttact
     6721 tgaaccttac atcgactcct ttgtcttctt tcgctttcac ggccaacgca cgcccttgtc
     6781 tctttacctc tcctgtgatg aattcaggta tattgtagga tttcataaaa cgaaaataaa
     6841 aatccgtatc cttctgaggt aacaggaaag gtttgcaagc ctgtcctttc tcatcgatat
     6901 aagcgataaa cggtcttgta tacaaaccat ctatccgccg gctgctaaac acgatccaac
     6961 gactatcgct actccatgaa tgatagcttt ccacatcgtc gctattcgcc gcctccaatg
     7021 gataactttg cagagtcgat aaatcaatca tgtacaaatc ggcatcctta tgccaaatag
     7081 agaaatttcc ataaccggac aaggtataga gcaaatactt tccatccggg gaaacccggg
     7141 gaaaagaaac gcttttatcg atctccgatg ccttatataa agtatcgact accgtcccga
     7201 aacggcgtgt agcgggatcg aacgagactg agcatagatc gtatctcact tgatcgtatt
     7261 ccttgggcat cgtacgggct ttagccgaac agaaatagag cgtatttcca tccggggaaa
     7321 atgtagggaa agtctcgaac gctccctctg aagacagcag cggagaagtc acgatctcat
     7381 gcttttgcgt atcatagacg accacatccg aggccgagtc gaatacctcc acccgattcc
     7441 tatcgttcat atgaaacgct tgcttggttt tattcacaga gaaagcgaca tattttccgg
     7501 aaggatgcca agaaggatag accagtggag aaagggtctg atcggtcttc gtattcagct
     7561 tctccacttt atctccatcg atcaataagg tacaagagta ggtctcacgc atatggaaaa
     7621 gcattttctc cggattctgc atacagaaag aatggcagtt catacagtta ttgccgctca
     7681 tcttattttc gatgatcgcg ttctccgtat aattttccaa gttacgttga tagataccca
     7741 tacggttcca caactcatag cccggttcga ttaaacgata agccaaccaa ccatcgaccg
     7801 gctccttcgc caccttgatg atgaagggga catacgcgat ccattcatca ttcacgaagg
     7861 cttgtacggt tacattcaga tgattcccgg aagcggcacg caacagcctt ttccaaccgg
     7921 aggccgggat cacgaaacaa gcgtctttcc cggtcttgat ctctaatttc tccgggccac
     7981 attcgagaat ggcacgggcc tcagtgcaaa catctttcag cttaaaattc aagggagcta
     8041 tattcggcgg gattgtcaca tccacataat ccggaaagat ctccggcttg acttccagat
     8101 tcttctgtat acgtaccgga ccggaacaag ccatcaagcc cagaatcatc cacagacata
     8161 tacatcttat tatatacatt tttctcatct cctatttaaa catataataa taccaatagg
     8221 tatcgccata agagcgatac atcaaaccgg gcagcgcatt actattattc cgcccagcga
     8281 gcacttgcct cttataatcg gtgaatcgcc ctacgataga ttccgagaca ccgaaacgtt
     8341 tccagtaatc cggatctttc tccgatagga tgatgaccgc ctcttgaaaa gagaccggta
     8401 aagaagggag taaatccgtt ccgtaatagg tttccaccaa cgtcttaaag cgcgtcacat
     8461 cttttgctaa aagatagaac acgccggcat agtggaaagc ggctttattg gaaggattct
     8521 gctccgccaa gcgaatcaag tccgtgtcga atccatccat ctggatcaga tgattctcag
     8581 ctagcaggtt cctgcgcata ttccccaata gaggatctgt ctcgaccgcc tcatcattat
     8641 acaggaattt ccgctgcgct ttggcccaat ccttataata gaaagtattc tctaagacag
     8701 cgatatattt ctccgcgacc ggataggctc cataaatcaa gttcgtttgc accaaacgtt
     8761 gcgtcatgcg gggatttcca tcacataaag cgccgatatt actctcgaat gccatctctt
     8821 gagccgcggc gacatttccc atcgtaaaat aaacatcact caacaaggcg gatatggtgg
     8881 tcgatttatt ccatgccacc attaatccac gaggcccgtg ctgcgtgtac ttaaacgcct
     8941 catccgccag aatacctttc cgggccaaag ccatattttg gtaacataaa tagagttgat
     9001 tagtggtcgg ctccttgcat gataccaaga tccggtccca ttgctctgtc cgagtaaaat
     9061 agtccatcat cttcaaacgg tatgatttct gttcgccata tagatcgaag cctttccaga
     9121 agataagccc taagataatg aattgggaga ttcccaacgc tagacgcttt ttaccagccc
     9181 atgattcctt gtttttacag aggcaggtta caaccaacgc cgcatagaaa gcgatccatg
     9241 agaaataaat taccttatcc ggcaccaaac ggaaataata ataactatcc ggtaaaaaga
     9301 caaagcggta ttctccgatc accgagtaac gcacacataa tccgcccaag atcaacacga
     9361 tcatcggtaa aatcgcggaa taataccaac ggggcgtccg gctcatggcc tcatatccga
     9421 ccatggataa ggcaaacaac aaagagaccg gcccggccaa cccaaagagt aacagggagg
     9481 caaacagact tgctatcaaa cgaggtatga aattccttat ccctaaaacg agatataaag
     9541 caagcagcat cataccgaag gcgaccgttc cttgaaacct gtaattaaaa tcccattgca
     9601 caaacaacaa ggataggacg ggaagccaag cccataaaat accatggctt cgcggatcga
     9661 tccgcttcaa gatcgcccag aacaaggccc ctaggcttgt cagcagggcc gccgttatca
     9721 tagctcccac attcgggaga atgaagaact gcaccaaaca accggagaga accatcgcta
     9781 aacctcccgg ttgcattaac ttatcgataa taaaaatggg agtcaactgg aataactggt
     9841 tctgctcgac acaataaaag tggtactcac tgaatatcct caagaagata aacagaaaga
     9901 caaatacgat tacatgcaag gccacgccgc tatacttctt catgatatca ggttcttcaa
     9961 ataaaaaccc ggatgtacgc gatcgctaca tccgggttcc tattcgtata aatatatgcc
    10021 ttatttagat tgaagaaaca cggagcgtgt tcaacaaatc ccggttaata ggcttatcat
    10081 tcttgatcgc tttagagaac ggtacataga cgatctggtc gttctggata cccatcatca
    10141 cgttacgctg gtcatccaac aaggcatcga tagcggccac acccatacga gtcgccaaga
    10201 tccggtcttg tgccgtagga gaaccaccac gctgcaagtg acctaaaata gagacacgca
    10261 cgtcgaactg cggatattcc ttcttcacac gctcagcgac acccatagcg ccaccggtta
    10321 cctcactttc ggcaaccaat acgatactac tgttcttgga cttacggaat ccattctcga
    10381 tcatctcggc caattggtct ttctccaagg agatttccgg gataatagcg gcttcggcgc
    10441 cagaagcgat cgctccgttc aacgccaaga aaccggcgtc gcgtcccata acctccacaa
    10501 aaaatagacg atcatgcgaa gtagccgtat cacggatctt atccacgcat tccatgatcg
    10561 tgttcaaggc cgtatcataa ccgatcgtcg tatccgtgcc atacaagtca ttatcaatcg
    10621 tacccggcaa tcctacgatc gggaaattaa actcctgagc gaaaatacgc gctcccgtca
    10681 acgttccgtc accaccgata gcgatcaagg catcgatccc atgctcttgc aacttatcat
    10741 aggcctgttt tcgtccctcg ggagtcttga actccacgca acgggcggtc ttaaggattg
    10801 ttccaccgcg ttgaattata ttactgacat tttgtgtctt aaactcttca atctcatcta
    10861 agatcaaccc tttgtaacca cggtaaatac ctttcactct cattccgtta taaatagcgg
    10921 aacgtgttac cgcacgaata gcggcattca ttcccggggc atcacctccg gacgttaaaa
    10981 taccaacaca ctttactgta gacatagcgt cattgatttt aatgttctcc ggcaaaagta
    11041 gtaaatattt agttatcctt ctgtctttct cccggaaagt tcacgtaatc ttaatcaaaa
    11101 tatcattccg aagcgttcaa ttccttgatc cggaccgcta cttcctccat caaccacttg
    11161 ggagtggatg tagcgccgca aaccccgacc cggcgcacgc cctcgggcaa aggctcggta
    11221 atctctgata cctcggaaat aaaaagcgta ttcgggttcg ctttccggca ctcctcgaac
    11281 agcatctttc cattggaact tttacgaccg gccacaaaat agacccaatc gtggctggag
    11341 gcgaacgctt ttatattcgg aagacgattc gccacctgac ggcaaatcgt atcgtaataa
    11401 ttaaactcca ccccttccgc catccgctgc ttgatctccg ccactaccgc cttgaatcca
    11461 tccaaggact tcgtggtttg ggaaaacaga ctgatcgcac gggtaaagtc cagacgatcg
    11521 aggtcttcta ttttctcgat aacaatcgcc gtgccttctg tctggcccac caagccattc
    11581 acctccgcat ggcctttctt tccatagata accaactggg tgttattcgc ccgggtctct
    11641 tgataacatt tatggatctt gcgctgcaaa cgcaagacaa ccggacaagt agcgtctata
    11701 atcgtgatat tgtttcgctt cgctaaagaa taggtagaag gtggctcgcc atgcgcccgg
    11761 agcaacacct tccggtctct caactttgaa aggccatcat gatcgatcgt atgcagcccc
    11821 atatgctcca accgctccac ctccaaactg ttatgaacga tatcgcctag gcaatacagc
    11881 gtatccgtat tacccagctc ccgctccgcg ctttctatgg cggtgacaac cccaaagcag
    11941 aatccggaat ctttatctat ctcgacttct atcatatcta taatatcatt aacaaacaag
    12001 cacttacagt tttcttaatt ttcaatcaca agaaactaaa gtttcttcat aacaaaacta
    12061 gagttttccc taagagaaac ttttgtttcc tagtaacgaa actatagttt tcattcgaag
    12121 agacaaaagt tttctttata ggaaactcca agcactcgtt tatgaaccga tcgctttatg
    12181 atattgttcc agcaaccaag tcttttgctc ttccaaggtc atatgggaat tatccaatac
    12241 caaggcatca tcagcttgtc tcaaaggact ttcctcccgg gttgaatcta tataatcccg
    12301 cttcttcaca ttctccagca cttcctcgta agaagcgggg atccccttcg cctccagctc
    12361 atcgacccgg cgcttggcac gtacctccgg cgaggcggtc acgaaaagct tcaactccgc
    12421 atccgggaat acgaccgtac cgatatcacg gccatccatc acgatgcctt tcgcctttcc
    12481 catctcttgt tgcttagcga ccaacgcacg gcgcacaaag cctagagtgg ctaccggact
    12541 cactttatcc gccacttcca taccacgaat ctctttctct acattcacac cgttcaaata
    12601 ggtatctggc cggccggtct ccgcattcaa acgaaatgaa atatcgatat catggataga
    12661 agccttcagc tcttcctcct taatcttctc tccctcaaaa aatccatgct ggatgcaata
    12721 caaagtcacg gcccgataca tggcacccgt atcgatatac gtatatccaa tctccttggc
    12781 aagatcttta gccatggtgc ttttgccact ggaagagtgg ccgtctatag cgataactat
    12841 tttcttcata tatatattaa tgtataggtt tattctgtca ccttcttaaa atcggccaag
    12901 gtcgtagata cgctaatcat catcgacatg gcggacggat gatatttcgc cagcgagaag
    12961 cccacgtcaa acatcttgat ccttacgcct gcgccagccg agaagccgga gaaacttccc
    13021 ccgcctttca acttcatatc catattgacc ttcggattga atcctacgcc cacccaaaag
    13081 ttctcggacg ggataaaatc cacgccgatg ataaaatgct tcgccaacgt cttaacgaaa
    13141 gaatccccgt catactcttt atccgtatta tcgatataat cgaacttcca acggttcaag
    13201 tattgggccg tcaaagaaaa acgaatcggg gcatgcgcca ttttctgcgt gatacccatc
    13261 tggatatccc aaggcatctt ttgtcgctca tcctcgtaag ctttcagttg cgcgccgata
    13321 ttcttcaagg cgaaaccaaa ggaaaagccc ttatccgaat tataataact caatcccgca
    13381 tccacgcata aaccgataga ggtataatca gccagccccg aatacaagaa cttcaacgat
    13441 aatccacccc gccaacgctc attcaagtca cgggagtaaa aaccgttcac gctgatatct
    13501 ttcgccgaca ggctcgctcc ggtcacgacg ttatccggta acacctcctt gatatcgcca
    13561 tagcttataa acgtagcgcc tacgccccaa gcccctttct cgccatgcgc tttcgtgaac
    13621 aaggcacttc ctacgttgat atccgagatg taattcatat aattcaagtt gatcatccca
    13681 tccatctccg cacctagcaa ggccggatta tggaagataa gcgaagggtc tctttctacc
    13741 aacgccacgg tatgcccacc caaggcgtta gcccgggtcg aggtcggaaa acgtaagaaa
    13801 gtatacgcct cactcccgtt ttgcgctgag acagacagtg taacaacgaa taaaatcagt
    13861 ataaatagtt tatttctcat attttcatgc aaaaaatcgt tcaaagatac attaattcgg
    13921 aaaaatgttt ttactttaca cccgcaaatc tcagaaatac ggatttcaca ttaacagaaa
    13981 cgggaaaaat gccaaaaagg tatattatcg ctctcatttt tgtttgatat atgaaataat
    14041 ttgtattttt gcagaagtga aaaacactta taaattatta taaacgtatg gaaattaaaa
    14101 aatcaccgaa agcggacctt gagagaggta agtctctaag tatcctgatg ggattcgtag
    14161 tgggcttagc tgtcttgttc gtgggcttcg aatggagcac ccgcgatgta atggtcgttc
    14221 aggctagcga gggtgtagca gacatcatcg ccgaggaaga agtggaaatc acgagaccgg
    14281 agaatacgcc tcctccacct ccaccacctc cagcaccagt tgtaaccgag gttttgaacg
    14341 ttgttgaaga cgacgttgaa ttggaacagc aagatatctt atcatcagag gataatcagc
    14401 aagaggctca aacagccgtt tatacaccgc ctgcagtagt agaggaagaa gaagaatccg
    14461 ctcagcagat ctttacggtt gtagaggaaa tgccgaagtt cccgggtgga gacgcagagt
    14521 tgctgaagtt tatcgctaaa tcaatcaagt atccggtaat cgcacaggaa aacggtatcc
    14581 aaggtcgtgt aatctgcgca ttcgtggtta accgagacgg atcagtagta gacgctgagg
    14641 tattacgtgg tgtagacccc tcattggata aagaggctct tcgtgtgatc ggtaccatgc
    14701 ctaaatggac tccgggtaag cagagaggta aaccagtacg tgttaagtat actgtgccta
    14761 tcacgttcag attgcaatag tataacatta aacatatcaa aaaggctgct ttattttcgc
    14821 agcctttttt tatttcataa ctccattaat tgatacagct atgttagcat tcgagaatat
    14881 acttcaaaga atagaaagcg agatctctca actacaattc accaatcctc ccaagagctt
    14941 atacgagccg atagagtaca tcttgtccct cggaggaaaa agaatacgtc cggcgttaac
    15001 gttgatggca tgtaatatat ataataatag tatagagaat gcgatcaagc ccgctttagg
    15061 tctggaagtt ttccataact tcaccttgct gcacgacgac ctgatggatg aagctgataa
    15121 aagaaggaac aaacctaccg tacacaaggt atggaatgcc aatacggcga ttctttccgg
    15181 agacgcgatg ctaatagcgg cttatcaatt aatcggatca acggaacacg gccaccttaa
    15241 acaagtgttg gatttattta cgcaaaccgc ggcggaaata tgtggcggcc aacaattcga
    15301 catggaattc gagtctcgca tggatgtgag cgaggaagaa tacatcgaga tgatccggct
    15361 aaagacagcc gtactactgg cctgctccct taagacgggt gccctactcg gaggtgcctc
    15421 acaggaagac gcaggcaact tatatgcgtt tggtatcaat ataggtctag cgtttcaact
    15481 gcaagatgat ttactagatg tatatggtga caccgccact ttcgggaaaa acattggcgg
    15541 cgatatcctt tgcaacaaga aaacattctt attgatcaac gctctcagac tggccaataa
    15601 agaacaagcg gaagctctcc gtagctggat ggataaaaaa gaattcgacc cggctcaaaa
    15661 gatacaggca ttcacctcta tctacaacga attgcagcta aaacaattaa cagaaaataa
    15721 aatccaagcc tattacgacg catccgtaga gaacttaaaa gctttacaag tcgcccccga
    15781 aaaattaacg atcctaaaag aggtttgtga tcatttaatg catagacaat cctaatccat
    15841 gaggttaata gacacacatt gccatttata tctggaggat ttcgatccgg agcaagacga
    15901 actggctcaa aaagcaaaag actcaggtat cgacaccctg cttctgccaa acgtagacct
    15961 gacgacgatt gacagaatgc acgatttatg cgatcgatac ccagagttcg ctttccccat
    16021 gatgggattg catccgacca gtgtggatag caattatatc gatatcctaa aacaaacgga
    16081 atcctatcta tctaaacgta cttattgcgg tatcggtgaa atcgggatcg atctatattg
    16141 ggataagact tatttaaagg agcaacaaat cgttttcgag gaacaattgc gttggagcat
    16201 cgatctgaac ctgcccgtag ccatccatac ccgcgacgca tatccggaag ttctggaatg
    16261 catacataaa gtcggagcgg aaagacttaa gggcgtattt catagtttta ccggcacaac
    16321 ggaagagctg gaagaaataa agaaactgcc caccttcaag atcgggataa acggagttgt
    16381 tacctttaaa aattcaaaac tgtccgaagt cattcggcaa acggatctta aaaagatact
    16441 cttggaaaca gatgcaccct atctttcacc agtcccctac agaggtagac ggaatgagcc
    16501 tacttacata tggaagacgg ccgagaaagt ggcggaaaca ttcggcctca cgctagagga
    16561 aaccgtaaac gctactcgaa aaaacacatt agaattgttt aaaagcgtaa ataaacccat
    16621 atagacactt tttttcgaat gaagtcaaaa tttatttcgt ggatattgtg tatatgtcaa
    16681 gcaaaaacta tagatttgtg cactgaaaag attgcatatg ggaatttttt cgtattttgc
    16741 ggtcgtttta gaagaagcta ggcgaataat tggagagatg ctcgagtggt tgaagaggca
    16801 cgcctggaaa gcgtgtaaac ccctaaaggg tttcgcgggt tcgaatcccg ctctctccgc
    16861 ggtggagaat accatgaatt aattaacaat aaaataaaaa caaataagag aattattaat
    16921 cttaaaaatt aaacacacaa tgaaaaagtt atttgcaaaa gcattcttgg gtttatgtgc
    16981 ccttggaact tctaccgtag cattcgcgca ggacgctgca gacgcagcta cagctgttga
    17041 aggaggtatg tatcaagcat taaaaacaaa gtttatcgaa ggtggtgccg acttcatgag
    17101 tttggttgct atcgctttga ttttcggttt ggctttctgc ttagagagaa ttatctactt
    17161 gaacttagct gaaacgaatt ccagcaaatt gttgaagggt atcgaagatg ctttagacaa
    17221 aggtgatgtt gaaggcgcta aagctatcgc tcgtgacaca agaggcccta tcgcttctat
    17281 cgcttaccaa ggattgatga gaattgacca aggtatcgac gttgtagaaa aatctatcgt
    17341 ttcttatggt ggtgttcaag gaggtctttt ggaaaagaat atgtcttgga tcacattgtt
    17401 tatcgcaatg gctccgtctt taggattctt gggtactgta gtaggtatga tcatggcgtt
    17461 cgataaaatc gagcaagttg gtgatatcag cccgacggtt gtagcaggtg gtatgaaagt
    17521 ggccttgatt actactgtag gtggtttgat cgttgctttg atccttcagg tattctataa
    17581 ctatttgtta agcaaattgg aggctatctt gaatcaaatg gaagatgctt ctatctcttt
    17641 gcttgacttg gttatcaaat acaacgtcaa attcaaaaaa taataacgaa ttatggcagt
    17701 tactaaaata agaaaaatat ccagttggac tttactgata agttctatta tcagtattat
    17761 tgttctgggt atgttttatg cgggtggagt cgttgaccct gccgctgaaa tgaaagagcc
    17821 catctatacc gggttattga ttaactggac ttcagtattg ttcttcgtga caatcatcag
    17881 tacaatgttg tttgccgttt ggcaattttt gacgttgttg aagacaaacg ctaaatcagc
    17941 gattatgtct ttggttgtat tggtttgctt cgttgccgtt ttgttcatca cttacacgat
    18001 gggtgacgca actcctttaa caggtttgaa cgcagactct caagtttaca acactccggg
    18061 ttggttaaag atcacagata tgtggatcat gtctacaatc gtacttttgg ttctgatcgt
    18121 agcatgtgta gtttggggtt ctgtaaagag aatcatgggt aaataatagt aataacgaac
    18181 tgataaaaca agaaagaaat gggtaagaaa agaaagacac cgggtatcaa tggttcttct
    18241 tcggccgata tcgctttcat gttgcttatc ttcttcctta ttactacatc aatggataca
    18301 gataaaggtt tggcaagacg tttgccgccc cctgtaccta aagatcagaa gaacgatacc
    18361 gatgttgaca tcaaaaagag aaacttgttg gttgtattga tcaacagtaa taaccagatt
    18421 ctctgcggtg atcaatttgt cgatatcaag caattgaaag aaagaatcaa agagttcatt
    18481 gataatcctt ataatgacga acataagcct gagcgtgtag aggctgatgt tccattcttc
    18541 ggaaagatga tggtaacgaa gaaccacgta atttctttac agaatgaccg tggtaccgaa
    18601 taccaagctt atatcgatgt gcagaatgaa attgcggctg cttataacga attgagaaat
    18661 aaggtttcta aggaaaaatt cggtaagaat ttcgctgatt tggacgaaga acaacaaaaa
    18721 gctgtacagc agatttatcc gcaaaagata tcagaagctg aacctaaaaa ttatggaggt
    18781 aaaaagtaat gggaaagttt agtaaagcgg gcggtcgtga aatgcccgaa ttgaatacat
    18841 catcattacc tgacttggtg ttcgctttct tgttcttcat catgatggta acatctatgc
    18901 gtgaggtaac attgaaagta gagttccatg ctccacaagc tacagagctt caaaaattgg
    18961 agaagaaatc tttggtaaca tttatctatg tcggtaagcc gactagagat ttgagagcga
    19021 agatgggttc tgaaactcgt atccaattaa atgacgcttt tgcggaaact tcggaaattc
    19081 aggattatat cgcacaggaa aagtccagta tgaaggaaga ggaccagccg tttatgacgg
    19141 tttctatcaa ggctgataaa gagaccaaga tgggaacgat tacagacatc aagcaggctc
    19201 ttcgtgaagc atacgcatta aagattagtt attctgccgc tcaacgtgtc gacgaataat
    19261 gatctacaaa tagaatatct aaaaaaggcg ggaaatagaa tcccgccttt tttatttcac
    19321 tccatagaca ttttggtgaa taatggtctt aactcgctta aaagatcgct ccagatcaag
    19381 ttccccatga gtcatcaaac gcatttctaa taacgcctct cctctacgat atggaggttg
    19441 gaaatataca tggtgatcca agacaaaccc cagacgttca taaaaaccga ttctacgttt
    19501 actcatctcc tctgtcggca tctctacctc taagacaacc ggatcttcgt ggagagctaa
    19561 aaaacttgtc attgctttcg ctccgattcc tccgttacga gcggactcgt cgatcgcgaa
    19621 atgctccgca taaacaaagc cctcaaattg ccatcccgta atgaaaccca cataaatacc
    19681 atcccgtagc aaggcataca tctcgaaacg gctatcttcc tccaaaagct tacgtaccaa
    19741 agagaaatca cgacgctctt cctcggggaa agaactagta tatgttttct ctactagatc
    19801 caataaagga tcggctatct cccggacagg cttactaatt attacatgat cttcgctcat
    19861 aaaaaaaaca cttaataatt gaataaagaa tgcttacaaa atcaaaataa tctaacataa
    19921 tctttaggtg attataagat tatcattata tttgtattaa atatgaaaga tataatctaa
    19981 cagtaataca aatatactga atatatggca catcatcaac tagatgaact ggacgagaag
    20041 atacttaaac taatcatcgg caatgcgcgt atgccatttt tggaagtagc gagggaatgt
    20101 aacgtatccg gagcggctat tcatcaacgc atacaaaagc tgactaattt aggggttatc
    20161 aaaggctcag aattcatcgt ggataacaca aaagttgggt atgaaacttg cgcatatatg
    20221 gggttattcc taaagtctcc cggacaattt ccaagcgtta cagaagcgct gttgcagata
    20281 ccggaagtcg tggaatgcca ttatacaacg gggcaatacg acctgtttat aaaaatatac
    20341 gcaaagaaca accagcattt gctaagcatc atccacaaca agcttcaacc attgggcttg
    20401 gctcgcaccg aatcgctcat atcctttaag gaggcattca aaagacaaat tcctattgat
    20461 ctggacgacg attaataaag gaagctaata taagaaaagg gtccgtaatt cggttgaaac
    20521 cggttacggg ccctttttat catgatcact aagcgctatt agaactcagc attattcggt
    20581 gtacgcggga aaggtatcac gtcacgtata tttgccatgc ctgtaacaaa cagcaaaaga
    20641 cgctcaaagc ccaaaccgaa accagagtga ggcaccgtac caaaacggcg agtatctaag
    20701 taccaccaca tatccttcat cgggatgccc aactcatcaa tacgagtcat tagcttatca
    20761 tagtcggcct cacgctcgga accgccgatg atctctccga tcttcgggaa caatacgtcc
    20821 atggcacgca ccgtctttcc atcctcgttt tgcttcatat agaaagcctt gatctctttc
    20881 gggtaatccg ttaaaattac cggacgtttg aagtgatcct ccaccaagaa acgttcatgc
    20941 tcagaagcca agtctacacc ccaataaaca gggaactcaa atttatgtcc tttagcgaca
    21001 gcctcttcca atatcttgat tccttcagtg tacggcaagc gaacgaatga gtctttcaag
    21061 accccttcca gacgagcgat caattcctta tcgaacatat cgttcaagaa cttgatatcc
    21121 tccatacagt tatccaacgc ccattgtacg caatatttaa tgaactcctc ggccaactcc
    21181 atattgtccg tgatatcatt aaaagcgact tccggctcaa tcatccagaa ttccgccaaa
    21241 tgacgaggcg tatttgagtt ctcagcgcgg aacgtagggc caaacgtata aatctgtccc
    21301 aaggctgtag ctgccaactc accctccaac tgtccggaaa ccgtcaagct agcctgcttg
    21361 ccgaagaaat cgtcctcata aatgatagag ccattctcat cctttttcaa gtcgtacaaa
    21421 ttcttggtag taacttggaa catctgtccg gcaccctcac agtcggaagc cgtgatgatc
    21481 ggcgtatgga aatagaaaaa gcctctatca tggaaaaact tatggatagc gtaagccata
    21541 ttgtgacgaa tacggaatac cgctccaaat gtattcgtac gaggacgcaa atgagcgatc
    21601 tcacgcaaaa actccatgga gtgtcccttt ttctgcaacg gataagtagc tggatcagcc
    21661 gtaccgaaga tctcaatctc ggtagcctgt atctccacgc tttgcccctt gccttgggat
    21721 tgtgtcaaga taccgtttac gctgatacta gctcccgtgg taatcggttt caagaactca
    21781 tcacccaatt tatctacatc cacaacgatc tgaacattat taattgtaga accgtcattc
    21841 aaggcgataa aattcacctg tttgctacca cggcgggtgc gaacccatcc tttcacgttc
    21901 acggtagtac cgaaagcttc gcttttcagc acgtctacaa tttttgttcg tttaattgtt
    21961 tccatctgta tcgttttttt ttattcgaaa gctcccatcc taagagcgtt cacttccctt
    22021 tcatttaagt aacgccattt accgcggcct aagttcttct tagtcaaacc ggcgaaataa
    22081 acacgatcca atttcgtcac atgatatccc aacgattcga aaatacggcg cacgatacgg
    22141 ttacggccgg aatggatctc gatacccact tggctcttat cgtcctcgct agcatagctg
    22201 atagcgtccg catggatctc cccatcctca agctcaaggc cgttggcgat tttctccata
    22261 tcctcgatag ccacgttctt atccaaccac acatggtaga tcttcttctt cttgaaagat
    22321 gggtgagtca atttagaagc taaatcacca tcgttcgtca ataacaagac acctgtcgta
    22381 ttgcggtcca agcggcctac cggataaata cgttcttggc aagcgttctt caccaaatcc
    22441 attactgtca agcgttcttg aggatcatca gaagtcgtta cgcaattctt cggcttgttc
    22501 aatacgatat acaccttgct ctcaatctga accggcttct cgttaaatgt aacaacatct
    22561 tgacgagtaa tcttagtacc caattccgtt accacgacat cgtttacctt aacagcccct
    22621 ttctggataa actcatccgc ctcacgacga gagcaaacac cagcgttaga taagaatttg
    22681 ttcaaacgaa tcggttcgtt cggatccgcc aagacttcct tatacttgat ctgtttcgga
    22741 cgcatgttgt aaccctgctg tctttggaaa ccacctcctc caccggaacg gcgattatta
    22801 ttgtaagaag gacggcgatt atttccatat ccaccacccc cttgacgatt accgccataa
    22861 gagttatcgt taccatacga acgtctgggt gcgtaaccgt ccccgccgct tgaacgtgaa
    22921 tcattgtaat caacccgggt atcacctact ctaggtcttc ttttcttcat accatccgca
    22981 gacattccct ctccggaagg actagtggaa taagcctttg ccggtccatc ataattagga
    23041 cgagacggac gattgtattg ccctcctcca ttcccatatg acgggcggtt atttccataa
    23101 gacgagcggc cgctgttgta gccaccttca cggttgttgc cataagacgg gcgattattt
    23161 ccatacccac catcgcgatt gttgccataa gatggacgac tattaccata gcccccctca
    23221 cggttgttgc catacccgcc ttcacggtta ttatcgtaag aacgcggacg gctcggacga
    23281 tccccgtatg aaggacggtt attttctcca taagaccgat acggtctacg ttcatagcta
    23341 ccctcaggtt tattataacc ctgattgtaa ggtcttcttt caccttcttg gtctgtgttt
    23401 tcccgtctga tacttggtat cacttttttt ggacgcggtt gagattcatc tctttcttct
    23461 gtactcattt gttataaatt aaacaatggt taaaaacttg gtagcctcac ggctacctgt
    23521 attatcacta aattcctgta taattatgag gcgttatagc ccttaattca tctttaatcc
    23581 ggtcgctaac attcaaggtt tcgataaact ccttgataga ttgctccgta acagtctggt
    23641 tcgtacgtgt caaagctttt aatgcctcgt aaggcttcgg ataaccctca cggcgtaaga
    23701 ccgtctggat accctcggct accacagccc agcaattatt caaatcccta cttagggcgt
    23761 tctcgttcaa taacaattta cccaagcctt ttgttaagct cttgaaggca atttctatat
    23821 gtgccaaagg cacgcctacg tttctcaaca cggtagaatc cgtcaagtct ctttgtaaac
    23881 gagataccgg caatttcgta gccaaatgct ctaaaatagc gttagcgatc cctagattac
    23941 cctcagcgtt ctcgaaatca atcgggttca ccttatgtgg catagcagac gaaccgatct
    24001 cacccgcctt gatcttttgc ttgaaatact ccatggagat atattgccag aagtcacgat
    24061 tcaagtcgat caagatcgta ttgatacgct tcaagccatc gaagatcgct gccagattat
    24121 cataattaga gatctgggta gtccactcct cacgcttcaa gcctaacacc tcactaacga
    24181 acttgttacc gaatgccctc caatcatatt ccggatacgc tacatgatgc gcattgaagt
    24241 ttcctgtagc cccaccgaat ttagcggaga taggaacggc ctttaacaat gccaactgtt
    24301 gctccaaacg gtaaacaaag accatcacct ccttacccaa acgagtcgga gatgccggtt
    24361 gcccatgtgt cttagccaac atcggaatat ccatccattc ctcggcgtat tttttcaagg
    24421 cgccgatcac ctcttccaaa cccggataat acacctcttg caaagcgtcc ttgatcgata
    24481 aaggcacaga tgtgttatta atatcctgag aagtcaatcc aaaatgaata aactcgtggt
    24541 atttctccgc aaggaaatga tttgtttttt ccttaataaa gtactccacc gctttcacat
    24601 cgtggtttgt cacgctctcg atctccttca ctcgtaaagc gtcctcctcc gtaaactcct
    24661 gataaatttt ccggagcccc ttttttactt ccgccgcatt taactcgctt aattgcggaa
    24721 gaaactcaga tagagtaata aaatactcga tctcaactcg caccctatac ttgataagtg
    24781 cgtattctga aaaataagcc gccagattct cagccttatt cctgtatcgc ccatccacgg
    24841 gcgaaatagc agtcagtgtc gataatacca tatacattat taatatagag tcgcaaagtt
    24901 aagtcttttc cattgaataa taaggtaagc aatcgttatt tttaactaaa tgccccgttt
    24961 ttaggaccat cagacactta cgtagccaca tccaaacaaa attcatattc atccacattt
    25021 tttcgtcaaa aagtttggtg gtaataaaaa aagccgtatc tttgcagcgc tttagagaga
    25081 taaagcgaac gaaaaaataa gtttaaaggg cgtttagctc agctggttca gagcatctgc
    25141 cttacaagca gagggtcggc ggttcgaatc cgtcaacgcc cacctttaaa tttattattt
    25201 caccgaaaga ttttcgggcg tttagctcag ctggttcaga gcatctgcct tacaagcaga
    25261 gggtcggcgg ttcgaatccg tcaacgccca cttttaaatt tattattttc accgaaagaa
    25321 tttcgggcgt ttagctcagc tggttcagag catctgcctt acaagcagag ggtcggcggt
    25381 tcgaatccgt caacgcccac aatagaaaag attgtttggt ttccagacag tcttttttta
    25441 tttaggaacc agagagttta cccgaggttc cagaaacttt tccaaagcaa gttaactttc
    25501 ctacaattcc ctatctcttc tgcgacaaga ggacagcgat cagacgatct aacgagaact
    25561 taccaggtcc tgctatatac atcaagataa aaatgaccaa gtaaacgaac gccaactctt
    25621 tcaaagaaaa cggatcattc ccgtgaatca cgaagaaagc cactcccatg gtaaaaatca
    25681 tcgggatcat tgccaaccga tagagcgcac cgagaataaa gccaatcgaa caaaaaagct
    25741 ccccaaaaat ggccaagcct agagaaaccg aatgtccaac tcccagtggg tccggaaatg
    25801 cggcggacat gctctcaaaa ttcgtccact tctgtatccc atgcgaaagc aatagacctc
    25861 caaataacaa acgaagcgcc aacaacagta acgatatagc tgtaccatcc ggcttcattg
    25921 gaaaaagaaa tttgtaaaat gctgacataa ttcccctatt ttttatctta tcaattcatc
    25981 tttctggtaa taaaacaaaa acgaagtaag gttagttcag caaaagctcc gggaattgac
    26041 aagcggctta tctttcgcct tgcaaaacgt ttgccactac tatcataaca ctatttacct
    26101 tattataata caacgacttg aaataataca tcttcaaaag aataacaatt taacaacatg
    26161 ctaattacct ttgctttccg tgttctttca ttacttaaat aactccatca taaacgtaca
    26221 taaaaacttt cggttttttc gtaagtttgt agtcgaaaat atatttcact gaatatgaga
    26281 aattaaatta aggagaacag gagtaacagt gaatatatca aatgagtaag tatattacga
    26341 attattacat ttagactatg cttttagaaa aactacttaa aggatttaat tatagcacca
    26401 gtactttcaa tttgaaggaa tctaagttat ttgaccaata ttttgaacga atattgatta
    26461 gtaaaggtac atttttggtc aaggaaggag aaatagagag gtatagttat ttcgtttttg
    26521 atggaatatt acgttgttgg ctattaaatc ataaaggaga agaacaaatc ttttggtttt
    26581 gtaaagaggg tacgttctca atgtcgaaca tatcttttac attacaaaca aagtctgcgt
    26641 ttaatgtgca aacaattgta gatagcgtta tttaccgaat agacaagaaa caagaaaatg
    26701 aactatacac cgctatacct aaggtaaaaa ctgtatttga agatttgaat gctatattgc
    26761 tgaataaact cttgaaaaga aatatcgact tgattaaata ttcccctgaa cagtattatc
    26821 tacagatgat tgaagaatat ggcattacac taaactatat accgctaaaa gatatagctt
    26881 cttatttggg tatcacacca caagcactaa gcagaatccg taaacgtatt ttttaactta
    26941 gattcagtgc tttaaatgta aaagttccga actttgtagc tttaaatagt aattacaatt
    27001 atgattaaaa aaattaaagt tacagatcat ccacgtttga tggaaatctg ggaaagttca
    27061 gtattaaata cacatgattt tcttaaagag gaagattttc tatactataa ggaacaactt
    27121 ccagtatatt ttcaacatgt cactctattc ggatttgaac aagagggaat cttagtagga
    27181 tttatgggaa tcgcaaaagg aaatcttgaa atgttattca ttgacaataa ttatcgaggt
    27241 ataggaatag gaaaaaaatt aatcacttat gccatagata atttgcaagt aacaaaagtc
    27301 gatgtgaatg agcaaaataa tcaagctgtc ggtttttata aacatatagg ctttaacaca
    27361 tacaaaaggt ctgatttgga cggagaaggt aaagaatatc ctattttaca catgcggtta
    27421 tagttttccg aaaaatcaca taaacaaaaa atccttggaa atctaatgat taccaaggat
    27481 ttcttgtgac ccgggtggga ctcaaaccca cgaccttcag aaccggaatc tgacgctcta
    27541 ttcaactaag ctaccgagcc aaagactgcg caaaagtaca tataatatct tagtttagca
    27601 aatacaggag agaaatattt tatttttgat attttgcata taagtattct gcttattctg
    27661 ccattttgca aataaaagcg atcacattct tgttattttg ccattaatca ttatctttgc
    27721 cgcacatatt tcacaaacac aaagtacaac aagtatatga gctatcttat taaacccgca
    27781 gggtataaag ccttacttaa cttatcccag actgaaatgg gaatcaagaa gatcaaggac
    27841 tttttccagc aaaacctctc atccgagctg cgcctaagac gcgtaaccgc acctttattc
    27901 gtacttaagg gcatgggtat caatgatgat cttaacggga ccgagcgagc cgtcactttt
    27961 cctatcaagg atttaaacga ctctaaagca gaaatcgtac attcactcgc caaatggaaa
    28021 cgactgacac tcgccgatta ccacattgaa gaaggttacg gtatttacac cgacatgaac
    28081 gccatccgct cagacgagga gctaggtaat ttacactctt tatacgtgga tcaatgggac
    28141 tgggaacgtg taatgagcga aagcgaacgt aagatcgatt tcctcaagga aatcgtccgt
    28201 cgcatatatg ccgctatggt ccgtaccgaa tatttagttt acgagatgtt tcctcaaatc
    28261 cgcccgacgc tcccccaaca gattcatttc atccattcag aggatttgtt acaaaaatat
    28321 cctaccttta caccgaaaga gcgggaagac gctattacca aggaatacgg ggccgtattc
    28381 attatcggta tcggatgctc gctaagcaat ggagagaagc atgacggacg tgctccggac
    28441 tacgatgatt ggtctacgat cgccgagaac ggacaaaccg gattgaacgg ggatttattg
    28501 gtttgggatg atgtactaaa ccgttctatg gaactatcct ctatgggtat ccgcgtcaat
    28561 aaggaagcct tgctacgcca gttggatatt tgcaaagccg gggagaaaaa agaactctat
    28621 ttccacaaac gcctcttgag cggtgaactt ccgcaaagta tcggcggtgg tatcggacaa
    28681 agccggttgt gtatgttcta tcttcgtaag gcccatatcg gagagataca ggcaagtatc
    28741 tggccggagg agatgcgcaa ggaagcacgt gcagctggaa tgatgcttat ttagttaaca
    28801 gccaactatt atattatgga cgtaaagatt gaagaaagct ggaaaaaacg gttagccgac
    28861 gagtttgaaa aagattattt caagcaattg accgatttcg ttaaacaaga ataccgccaa
    28921 ggtactgttt atcctcccgg tccttatatg ttcaatgctt ttgagcactg cccgttcgat
    28981 aaagtgaagg tcgttatcct cggccaagat ccttatcacg agccgggaca ggcgcacgga
    29041 ctttgtttct ccgtgcagga tggggtacct tttccccctt ccctcatcaa tatattcaaa
    29101 gaaatacaag atgatttagg gcatccggtt ccaacaaccg gcaacttgat tcgttgggca
    29161 gatcaaggcg tattactgct aaacgccacg ctcacagtac gagcgcatca agccggttcc
    29221 catcaaaata gaggttggga gacctttacc gatgctgtta ttcatcgtct ggcggctgaa
    29281 agaagccata tcgtttacat attatggggt tcctacgcac aaaagaaagg tgctttcatc
    29341 gattcatccc gtaacctggt tcttaaatca gcccatccgt ccccactttc cgcttaccgg
    29401 ggattcttcg gaaacaagca tttcagcaaa gccaatgatt atttaatcgc aactgggcaa
    29461 actcccatcg aatggtaaga tcattgagaa ttgaaaatta gctatacaat ccaataattt
    29521 tcaattctca attttcggtt cttaatacca ctgctgtcca tccctataat tacttctctt
    29581 atcatacttc aaatctttca ataaagcaga gcttacagcg atactgaatg tataggattt
    29641 ataaggacca accggaacga aactagccgt catttgccag cagtgcaagt tacgagttac
    29701 gttacaagtc atataagaga tcttcttagc gtcaaaatca taagtagcgt taaagttaaa
    29761 acgccagttc tttgtcggct ggatatttcc gttaaagctc aaagagtgag tcaaggcgta
    29821 atcatactcc agtttagaac gattaaaatc accataccgc aaactcaaac cataactaaa
    29881 cgagaggctc caaggaatct tggaaattaa atagccatcg gcatctgtct caccggtctc
    29941 tttctttttg cccaacagac ggccaccact ttccttattc tcgccttctc cttctccatc
    30001 cgggttcaag ccatccggat ctgcattcgg atccgtagaa gccgattgat tcccagattt
    30061 atccgatgaa ctatcacctc ctccaaacaa cttcttgaac gtatcattat taaatgtata
    30121 agaaaaactg gtgctagtcc ctctcaaacg gccaataccc ttgcctgctt tccaacgggg
    30181 aatatcgaca cgatgcccat tctcatcgta cgtataggta tcgaactgac cattcaagtt
    30241 caacgtataa ctcttggata atttcaaacg taaaccgaca ctcaagtcac tccacttaaa
    30301 tgaatccgcc gccatattat aactcatgcc taacgacagc ttatcgatca gactaatttt
    30361 cttgaatcca gtagagtcct tatccgaacg caccttcatc tcgatattgt tatttacgtc
    30421 aaaactgata tttccttgtt ttcccgttcc cggaacgcca tacatattat gagcgaacgg
    30481 agaatacgta tattcacgat cctcaccatt cgcgtcttga tatacatagg tctgataaaa
    30541 gccaaaacga gaagaagcga agtccggctg ggcgcttacc gtaatagacg gctcgaagcg
    30601 gtgacggatc atctcaacct tattacccaa gaatggcaac ggtttataaa aaccatacaa
    30661 ggtagtagac gcagagatag aagcgttaaa atcgtaaata cgataaaaac catacgtagt
    30721 gtcgcgggct accaaagcct gtttctgcgt atcatattcc tgttcgatct tgctggtgta
    30781 ccaacgttcc ttataattga aagagggaga aatattcaag tacttgagca cggagaatgt
    30841 agcgcttacc ggaatcgagt gctgcatagc attctgccaa tctttgatca aattcgattt
    30901 gaataataag ttttcctttg tcgtgatact attactgaac gtaccggaat aactcatgga
    30961 gatcttctcg taccaacgct ccttcccgac cggatgcttc cgcttgaaag ggaagatacg
    31021 gctcatcgta accgtcatgc taggcaaggt tacggcgata gaagaatcac gggtcgtctg
    31081 gtttatactc atcgtaccgg agatcgtgaa cgggttattc gggaaacgtt tcgttacgtt
    31141 aatggatgaa ctcttcgtat tctggttcac gtcggcatac ccgttcgcgt tcggatataa
    31201 actgttctga ttattgcggt catacgaaga agtagagaag tttacgctcg cagagaaaga
    31261 cagataagga ttcgccttag ggtcttgcgt atgcgtccag tttaccttga agtccttaga
    31321 caaactatag tcgggtaatc ccttgtcacc caatttcgtc accaaataag aagcattaaa
    31381 actacccgag aatttataac gtttgcggta agccgacttg gccgacaatc cccaagatcc
    31441 tttcgtataa atctccccca ataaagccaa gtccatataa tcgctcaagg cgaaataata
    31501 tccaccgtca cgcaagaaga aacctctggt agactcgtct ccgaaagtcg gcataataat
    31561 accggatgaa tatgtactcg agaacgggaa gaaacagaaa ggtaacccga tcggatacaa
    31621 cggcacgtcc tccaagacca gatagaccgg acccgttacg atattctttt tcgggcgcac
    31681 cttcgctttc gtcatctgga tgtaaaagtg aggatgctca tgctcgtcgc aggtcgtata
    31741 cttaccaccc accatgttca agatatcccc ttccatcttt ttcgttcgcc cggcggtaac
    31801 atacccttcg ccctgctggg taatcacgtc cgtgatatat cctttcttgg taccgaaatt
    31861 ataccgcatc gtcttcgact catattgctg gtcgccctcc ttaaacaacg gatagccaaa
    31921 ctcctgcccg atagagtcga gtccaaactt agcgaacacg atgctactat ccatattcat
    31981 ctcgatcaat tcggattgca gctcgatatt ctggtatttg acatcgcctt ccccgtaaag
    32041 atatgcccag ttgccagctg tcatcacgat agaatcggtc gcttgataac tgaccggagc
    32101 atctagcccg gtctgctttt ctggaatcga atctcccgct aacgttgtac tatccgtagg
    32161 agccaccaag agagaatcag tctgcgccaa gctatcggca ggagcgacaa tctcctgcgc
    32221 ttgcacgccc aagcctccca agaggaaaac gaatagaatg attaggactc tatatatcaa
    32281 aaacattact tcgttctttg cagtgtgtta cagcgtgcaa atgtataata aataaacgag
    32341 cccttatgct tttattcccc taaaaagagt ttacaccagt gttcaaactg ctcaactgtc
    32401 tcatttccat acttggataa gctctgtttt atcttatcag ccggtttctc tttcgtcaat
    32461 ttagtcttgc taaagaattt atcagcgaaa cagatcaatt gttcttccaa tgacacggga
    32521 cgcatatccc gatgtggaac aggcaagttc cgttcctcga tcatggcaag cgaaagcccc
    32581 gtccccgtat gcctctcgca aactaaggcg tggcgaggat acccctcttt ccgcattaaa
    32641 tcggctccca gatagccatg acagatataa tcggcctccc catggcaatc gatatccggt
    32701 gcgttacaca aaaagatccc tatgtcatgc aacatcgtcg cttcctcaat aaaagtcaga
    32761 tccagattca tctccggatg caaacgggcc aatgctaatg ccttatccgc cacgctacgg
    32821 ctatgagtca ccaaaatccg gtaggcatcc gaactttccg gataatattt ctttattata
    32881 tcaagaggtt tcatcctatt tatttttttg cgagacaaaa ataaacaatc tctctcacat
    32941 atactacttc tcatcactga tacccctgaa accaattgcc cagcttcaaa tcttttatat
    33001 ccgcacctgt ttcccgttcg cctctcaaat actcagagaa gtaatcgacc atccgccagt
    33061 aataatattc attatagtca tcaaaatgat gacgttttcc cggtacgatc aacatatcaa
    33121 agcgcttgcc cgccttgatc aactcgtcca cgacaacaat ggtatttgcc ggatgcacat
    33181 tattatcgat atcgccatgg attaataaca gatggccttt caagttcctc gccaattcct
    33241 gattggtcgg gatgcgaata tcgaacgaga tatttcccat atcatccgtg atctccttta
    33301 ctccatggtg tttctctccc caccaccggt tataaatgtt attgtcatga ttgccggcac
    33361 aagataccgc caccttaaag aaatccggat aaagcagcat agccgctgta gacatgaaac
    33421 cgccaccgga gtgtccgtgt atgccgaccc ggttgatatc catgaattta taacgagcgc
    33481 acaactgctc gatagccact ttatgatccg ccatcggata atcacgcaaa tttccatatc
    33541 cataattatg ataccacttg gagcgactgg gatgccctcc cctgtgtccc atgcaaacca
    33601 cgacaaatcc ggcttgcgcc aaacgatccg tacgaggatt caacggaatg tagcgaaaga
    33661 aagttccctc ctgttgcggt ccggggtata catagttaat gaccggatat actttcgtgg
    33721 aatcaaaatc aaaaggctta tacatgacac catacaaatc ggtcacccca tcggccgcct
    33781 ttaccgaaaa aggctcaggg aatttataac ctgccatgaa taattgggag aagtcactct
    33841 cctccaaggt catcaatcgg ttaccttggt tatcatacaa tgccgtagcc gggatcgtat
    33901 tgacacgaga atagttatcc acgatatatc gcatggattt atccatagag accaggtgga
    33961 aataatcgcc cggagtaatc agctttaagc ccgaaccatc cagattcacc cgatacaaat
    34021 gctcgtaata aggagtcgta tctccctttt cccgggcatt cgccttgaag taaacgacac
    34081 gattcttact gtccacgtct acgatggcgt ccacatgcca aggccctttg gtgatacggt
    34141 ttttcaaatt tccttgcgca tcatatagat acagatgcgc ccaaccatcc cgttcgctcc
    34201 aatggatcaa ttccttacca ttatcggtca tcgctagcgg gcgggtttcc atagaagtat
    34261 ttagacgttc ctcaatgatc gcttttaccg aatcctcccc gatcgtatac gaacagatat
    34321 ccacccgttt catatcccgg ctgacacggg tcaaatagaa ggtctggtta tctcccaacc
    34381 agatcgagtt ccgagtgagt cccgtacgct ccttatccgg cttggaggct agattgattg
    34441 tttgatcttt aaaacaatcc acccggattt ctttccgctt cccggtattt tccaaatcaa
    34501 agagatataa atgaacgatt ggagaacccg tctctcccgg catctgatat ttataggtct
    34561 caagtgtagg acgaggtttg gcgatcgagt taatcaccca taaatcttgc accgcacgtt
    34621 gatccgacaa agtcgcagcg aaataacgac catcgggaga ccagttcccc attacatatt
    34681 tccgcttatg gtcacataaa gtatcggtat tcaagaaggt ccggggcata ccaaagccaa
    34741 aatctttttc gccatccgta gtcaaggcga tctcggatat cgtcttatcc tccgggtcct
    34801 tcacggcctt ctcataatcc tcataactca tgacatacag gttcaaatct ttcgcaaaga
    34861 cgacccgctt tttatccggc gatatattcg cccaacggat tttagcagga atctcgtctt
    34921 tcgtaatccg agtcaaccgg gaggacggat aatcatacga gaaaaaatag ttcccgttcg
    34981 taccctttat cgagaaagta aacgtgcgat cattttcctt taaacgtaaa tcttcgatag
    35041 gaagttgttg tccggtaaaa ggctctctca cgatctcgct tatctgtgcc gccaactcat
    35101 cccgatcgaa taataatcgt ttatttctcg aatcggggtc caccagatac cagtttgtcc
    35161 cctcactcgt cttatactca taccagaact tgtcactatt attaaaataa ttgggagtaa
    35221 gggtataaga gaaaagtaac tgttccgcat tcgacggggc gaaacggcgt gcctgcgtat
    35281 attccggtag gacatcttgc gcataggtaa aaggcaccca tgataaactc aagaaggcta
    35341 ccgcataaaa aagtgttttt acattcatag attcttagta ttgtctgtta ttcgcctcaa
    35401 aagtataaac tttccgcaag ataccaagca gatagcgatc attagttatg tgtaagatac
    35461 ttcttctaca agctactaga aagataaata acaactttat tagtaacaac tttattacaa
    35521 acctaatatt gattatcttt gcgatagaat aatagttgaa aaatcatgga gaataagcct
    35581 tttatattcg gagtcgcgac atcgggcgat aattttaccg atcgcaagaa agagacagag
    35641 cgtctattgt tgaactttca gcatggtgta aatacggtac tgatttcacc tcgtcgttgg
    35701 ggcaagactt ctttagtgca gaaagcatgt cacttggcgc aatccgacaa attgaaagtc
    35761 gtgtatcttg atatattctc atgccgtagc gacagggatt tttatgatgc gttcgctgca
    35821 gccattctca aacaaacttc ctcaaagtta gatgaatggc tggagaatac caagctattc
    35881 ctctcacgta tcagccctaa aatatccata ggcaccgatc ccatgacaga tttttccata
    35941 tcacttgaga tgaatcctca aagtaatgat gttgatgaga tattacaact tcccgaaaaa
    36001 atagcgcaaa agaagggata taatattgtc gtatgtatcg atgaatttca acagattgcc
    36061 gaatttaagg attcgaagac attccaaaag cgattacgtt ccgtgtggca attacaaaag
    36121 tcggtgtctt attgcttgtt cggtagcaag aagcatttga tgaatgaact atttgaaaaa
    36181 aagagtcttc ccttttataa attcggcgat gctatttatc tgccaaaaat cgggacttct
    36241 gattggatca attatatatg tggtcgtttt gaggctacag gtaagcagat ttcaaaagaa
    36301 ctggctgaaa aaatatgcca aagggtagac aatcattcat cctatgtgca gcaattagca
    36361 tggttggtat ggattcatac agataaggtc gctacggagc agaactttga ggaggcatat
    36421 caggatatca tcgatcaaaa cactccgcta ttcgagaaac agaccgaaag tctgacgact
    36481 tatcaaatga attttttgcg cgccattcta gatggagtac atagcgagtt taccacgcaa
    36541 gagattctac agaaatataa acttggctca tcggcaaatg tcagtatcgt aaagagggca
    36601 ttagttaaaa aagagttgat tgaaatagag aaacgcaagg tcatcattcc agatccggtg
    36661 atgaaagtgt ggctaaaaaa ggaattggga ggcgtttaag acaacgcccc ctagccttct
    36721 gatatgaaaa gcaagggggc atcttctatt tatcttcacc agtcctatta actgccaacc
    36781 tgaacgagcg tcacgatcgg acgatcttgc gcgtcttcaa atacggtgga ttttccggtt
    36841 tccatatctt taccaagaaa gccggacact acttagtaag tagaccttca tcttcttagt
    36901 aagtagacca gacctctatt tagtaagtaa acagggggtc tgcttactaa gtagttttca
    36961 tcctactcat agagtagatc ccggactatt ccgcaagaga tttcggctta taaagcgaca
    37021 agccctgttt tgcggatacg gaagaaaaag tttatctttg cccatataca aaataagacg
    37081 actatgagca gggatattcg ttggttgcaa cgtttcgata atttctccaa agcatgtgcc
    37141 cgtttattga caataacgga tacgatggaa tatgatgctt tatcggaact ggagaaagag
    37201 gggcttattc aacgttttga atatacgttt gagttggcct ggaaggtgtt gcaagattat
    37261 atgcaatatc tggggttcca attccagaca ggcccgaaca cgacccttca gttggctttt
    37321 gagaatggat tgataaagga tcatgatcga tggcgaaaga tggcaaaagc ccgaatcctg
    37381 acctcgcata catacaacga gggcgaggcg gatgagatcg caaaagggat ttacgcagac
    37441 tacgctccct tgttaaggga actaagggat ttgctgatta ttcgtaagaa cgagacggag
    37501 aacaaagatc tattttaata gtttattatg tttggattaa gcgataacgt ggttgaagag
    37561 ttgcgtgagg tatttcgcaa gtatggcaac atacggcgtg tacttatctt tggctcgcga
    37621 gccaaaggca cgagtcatgc aggctcagac atcgaccttg ccatggatgg agaagatatc
    37681 acctttggcc aacagctcga cataaacaac cgtatcgatg atttgggttt actttacaaa
    37741 gtcgacttgc ttaattatca gaaacaaaaa gggactccta tcggggaaca tatcgaccga
    37801 gtaggtaaaa ttttctattc aagatagccc cgcattcatt tctcacaaac atttcgtact
    37861 ttcgcgatca gtacacagtg atatattata taatgtaatg aaacagatct ttatatttct
    37921 agtcatactt tttagcttga cgccaacggt ttattcacaa aacgccccgt taaagctagg
    37981 tgccgagcgg atggatgtcg tcacccgttt gcttaaggat aagcgggtcg gattagtggt
    38041 caaccagact tccattttgg aaaagcggca gattcattta ttagatgcgc tagtagcgga
    38101 aggcatagac gttaagaagg tgttcgctcc ggaacatgga tttcggggaa ccggtgacgc
    38161 cggagaggag ataaaagata gccgggactt gaaaacaggc atccccatca tctctattta
    38221 tgggaaaaac aagaaaccgt ccgccgagca actgggcaac ctcgacgtga ttgttttcga
    38281 tatacaagat gtaggtgccc gtttctacac ctatatcagt acgatgcatt acgtgatgga
    38341 agcctgcgcc gaaaacaaca aagagtttat cgtgttggac cgcccgaacc caaatgactt
    38401 tgtagacggg ccgatccgcc aaaagggatt tgagtctttc gtaggtgtcg atccgctccc
    38461 gatcttgcac ggcttaaccg taggggaatt ggcatggatg atcaataagg aaggctggct
    38521 gaaaagtacg cccgatacct gccggttaaa gatcgtaaag atggagaatt ggaaacacgg
    38581 agatccctat tggttgccgg tcaagccctc tccgaacctc ccgaatgacc agtctatccg
    38641 cctgtatccg tcgctttgct tttttgaggc tacgaacatt agcgtgggaa gaggaaccta
    38701 ttatccgttt caagtactag gtttcccgga ccctaaatac gggaatttca cttttacccc
    38761 gacctccttg cccggattcg ataccaatcc cttgcaaaag gataaagtat gttacggcat
    38821 cgatctgcgg gaatatccgt tcgaaggagg attaaccttg cgattcttcc tcgacttcta
    38881 caataaagcg ggaaaggatc aagccttttt cttctcccgt ccgaactggt tcgatttatt
    38941 ggcaggcacg aagcagctcc gctaccagat cgtaaggggc ttatccgaga aagagatccg
    39001 ggaaagttgg aaacccgagc tagatcaata caaggccatg cgtaaaaagt atttacttta
    39061 tcccgactat cctactcaaa ataaaaaata agaacgaatg aattattggg aatcgcatac
    39121 ccaagtcgcc gtacgtttcc gccgattcga ccggaaacgt tacgccgcgt tccggagtat
    39181 gcacaaagtc attaacattg gagtcgtaac agcaagtacg ctactattcg ccctgcccga
    39241 cacggcgcaa gctcaaaaga caatcgagcc taaccggacc ggcgaggaag cttccgtaga
    39301 gctggaagag gtagaagtta ccgcctcccg tgcgcctatc gcacggaatc aagcgaccaa
    39361 gatcgtgaca gtcattcccg cccgtgatat cgcggcggca cctgtcacca gtatccaaga
    39421 tcttttagaa tatgccgcgg gaatagacgt ccggcaacga ggagaaggag gcacccaagc
    39481 cgatatctcc atccggggag ggacgttcga ccaaatagcg gttctcttaa acggggtcaa
    39541 cctctccaac ccacaaaccg gccattatag ttttgacctc ccggtgaatc tctcggacat
    39601 agagcgcatc gaggtggtat ccggcccttc ttcccgtata ttcggggcca gcgctttcgc
    39661 cggagcgatc aatatcatca cgaaaacagg aaaagagaac aggatctcga ccgacaatta
    39721 cgccggaatg cataagctct ggaaactgga agctgccatc aatcacgcga ccactcattt
    39781 cggacagcgc ctttccgcag ggtatacctc gtccggaggg tatatagaca atacggactt
    39841 caaacaatta aatcttttct ggcaatcgga acttaaaagc gaggaggccg atttccaatt
    39901 ccaagccgga tacaacgaca aaggttatgg agcgaatagc ttctactccg cttcctatcc
    39961 caatcaatac gacaagactc gccgcttctt cctctccgcc ggaggagaaa tacatggcaa
    40021 aatcaagttc acccccaagg tatactggac ccgacatttc gaccggtacg agttgttccg
    40081 tagcgatccc gccgattggt ataccgggca taattaccat gagacggaag tattcggagc
    40141 caacctcaac gccacgacac agtggaaact aggaagaacc agtatgggcg tggaattccg
    40201 aaacgaggga gtaaagagta acgtattagg caagccgatg aaggaaccgc aggatgttcc
    40261 tttcgagaaa gaagggcaat atctaaaaag cgataaccga agtaatatca gctactttct
    40321 tgagcataac gtattattac gccgcttcac gttgtcagtc ggggtcttgg caaactataa
    40381 ttcggcctta aacgaaggga ttcatttcta tccgggaata gatgccagtt accgtatcgg
    40441 ggacaatttc cgtctgtatg ggagctggaa ccgggcattg cgtatgccga ctttcaccga
    40501 tctttattat gagggtaaga cgaataaagg aaatccggac ctaaaaccgg aggaaagcga
    40561 ggcattcgag gtcggactga aatacaacac ttacttcctc cgggctcata tagccggctt
    40621 ttaccgaaaa ggcaagaaca tgatcgattg ggtgaaagag aaaccggaag atatctggga
    40681 aagccaaaat ctgacaaaag tcgataacct tggtttcgag actaacctga gtttattacc
    40741 gagggaactg ggcaacaaac ggttctttat ccggaaaata gaactgggat atgcgtttat
    40801 ccatcaagac aaggatagtg aggggtatat atcgaattat gcgttagatt atctgaagca
    40861 caagttcacg gctcaattaa gccattctat ctggaaaggt ttttcggcca cttggtatgt
    40921 ccgttggcaa gaccgggcag gtagttatac taaatacgag aatcttaagc cggcttatga
    40981 ggaaccttac gctccttatt gcttagtaga tatgaaagta aattgggaat atcagcggtt
    41041 aaatctatat gcggagttaa ataatctgct caattccact tattatgatc tgggaaatat
    41101 cccccaaccg ggtatttggt ttaaggcagg attccgttat agtttcaaat attaataccc
    41161 agttgtagag acggggcgtg ccccgtctct acaactgggt gattttattt ttgctttttg
    41221 atcaccaaca acttatcatt attggtcccg aacaaagcga tttccgtaac aggagccgcc
    41281 tcaccctgtg cctcaaagcg caccacctta ttaagcgctt ccagcaactc ccgctcgccg
    41341 ctcatatccg ggcaagccat tcgggtagtc gctacctgtg ggaacttaat gatattttta
    41401 taagcatcat tatattcgat cttccccatc aaccgattgc aaccggcatt tcctgaaagc
    41461 ccttgacgag ccacgtcgaa caccaaaacc tgatgagtct cctcgggatt caacgtctta
    41521 ccgttcatct ccacgacacc ccattcacca tccagatccg agaaagaagc taccaccgct
    41581 ttcttggact tacaaccggc gaacaaaccg acgcctacca aaagcaggca aatataaaaa
    41641 agaccttttc gcattaattt ctctccaata ctaataatac attaccatct tggtctacca
    41701 gcaacatctc attctcatct tttccggcct tcacggaacg aacctgatcc atcgattgaa
    41761 gcacgctcgt ctccaaatcc atattcggac aagccatcat cgtcgtagcg cccggagcga
    41821 tcgtaataga agatacatct tccggatcta acgtgatcgt cgtattgaat aaattacagc
    41881 ctgtatttcc atgtaatttc ttctcagcca tattgaagtc catctgtggc aggccttctt
    41941 ccaagacttt ctcacctttc acttctacca cattccattt accttccaac ttcttcacat
    42001 ctgtcttgac gtctgaacaa gaaaacatca tcccaacgaa agcgggaagc aaaaacgcat
    42061 aaaacaatac ctttttcatc ttcatcataa tcttttataa aatatctatt gtaattagta
    42121 agacgcaaat agaaggcaaa atgttcccaa gagcaccctg ttttagctta tattaacagg
    42181 gttcttgatt aacatcctct ttttccactt ctgcgttcgc caccgcaaac agagtaccgc
    42241 accccgggaa cattcgtcca aagcaaaagc gaaccacatc cccgctaaac ccaaaccgaa
    42301 cacgattccg aacatatatc cgcagaacac ggcaaagaac cacatgcaaa ataactcgat
    42361 gattaccgga accactacat cgcctaccga acgcaaacag aataagaaca gcagtaccgt
    42421 ggcccgccct tgctccaaga gtacatctac cagcaaggct cccatcgcaa tcgttatgat
    42481 tgcttgattc tcagtaaata tccctaataa aggacgtccc agcagataaa ccccggtact
    42541 agcgaccagc gtaatcagca acgacctcct ccaagcatac caactcaata aataagcggc
    42601 ttgcttcttc cttgcgccca ccaaattgcc ggtacaaata gaagtagctt gcgcgatcga
    42661 caaagagaag atatagccga ttatcacgat attcatcaca taaacacgcg ctgtcaagta
    42721 ctcattaccc agcatattga tgaagtaaac gatcgtcacc tgcgaggcat catacgagat
    42781 ttgttccgcc gccgaaggca aaccgatctt caacacatct ttcaacttct gaaacgggaa
    42841 cggacggaaa taagccaaag ggatacgagg caccaaccgc ttgaacagca tgataaacaa
    42901 aagtgtcatc gccactcccc ggcaaacaga ggtagagatc gccgctcctt gtacaccgag
    42961 ggcagggaaa ccgaaatggc caaatatcaa cgcataattc ccaaacacat tcaatacatt
    43021 gatcagcaag gtcacctgca tcgcgtaatt cggcttgttc gccgcacgga gcaccgccga
    43081 tatcgtaaaa ctaaccgctt ggaagaagcc gaaccctccg acaatgtgca tataagtctc
    43141 agcgtccggc atcagatccg gacggatatc catcaggacc agcatctcct ttccgaacaa
    43201 gaaaagcatc aagctgatca agcaaccgat tcccgcgtta aacagcaaag acgtccctaa
    43261 tacctgaata aaacttttat gatccttcgc cccgaaatag agggcgcaca tgacggaagt
    43321 tccggtcgtg gtaatattga acagcaggaa taccatgttc agcaattgat tcaccacacc
    43381 taccgccgcc accgcattat cggaatgatg gctcagcata agcgtatcca ccacgcctaa
    43441 agtcaacatc agcaaggttt ccagaaagat aggccctgtt aatttaaata atttgcctct
    43501 cagccctctc ggggcacgga atagtctata catgtccatt gatctgcttt ctacctaaac
    43561 acctttttta cgagtccgcg aaggtacaaa gctttacgct aaataggttt cgctatttct
    43621 attattttcc gtaagtttgt atccggttga ataatttttg atgaacaaac gaagacaaat
    43681 ggacaagaaa ctacctatat gtatcgtatt agtcatgttg atgagttgtt tctcctgcaa
    43741 acagccccaa cagcccacgg aagacgcaga catggatacg cagtgggtgg atagctcaca
    43801 gcatctgtat caatacggca tctgtatcga ttccttggac gtaaaagagt atttgatgaa
    43861 aaacggggat aatcccgcct ccatcttctc cgggctgggc ttcacggcct tgaaagcaga
    43921 cagtatcagc agggcatcca cccatgtcct cgatccgacg aaactgcgag ccggcatgca
    43981 ttattacaca ttttccacgg tagattcctt ggagacgatc cgatatatcg ccttcgccaa
    44041 gtcgctgacc gattatgccg taatcgactt gaccggcgat acgatcaacg cctatgaatt
    44101 taataagccg atcaccctca agaaaaaata tacggaagga gtattaaact cttccctatg
    44161 gaacgtgatc aaggccaacg gaggtgatcc gtatctggcg atcaagatat cggacgtgta
    44221 cgcttggcaa atcgatttct tcgatatcaa agatggagac tcattcaagg ttctatacaa
    44281 tgaggcttac atcgacgata ccaccgcctt gagcatcgcc tctatcgagg gggcgatctt
    44341 tacgcatcaa ggcaaagagt ttgtagcgat tcctttcacc caagacagta tcttcgaata
    44401 ctttgatgag gaagggaaca gccttcgcaa agcgttcttg aaagccccat tagacttttt
    44461 ccggatcaca tcccgtttta cgaacgcccg tttccacccg atcctcaaac gataccgggc
    44521 gcatcatggg gttgattacg cagcaccgac cggtacaccg gtacgcagca tcggagctgg
    44581 tacggttatc gccaagggat atcaaaacgg cgggggcaat ttcctgaaag tgaaacataa
    44641 ctccgtatac accacgactt atatgcactt aagccgcttc gccaaaggaa tccaagtagg
    44701 cagccatgtg caacaaggcc aagaaatcgc ttatgtaggc tccaccggac tctctaccgg
    44761 accgcatcta gacttccgtg tccacaaaaa cgggcaacct atcgatccgc taaaaatgga
    44821 agctccccct tctgaaccgg tgaaaccggc ctatagagat agtttcgctt tcgttaagcg
    44881 gcaaatcttg gcggaaatag atagctttca tgtagccaca gttagtaaag catctgttat
    44941 atatgagaaa gatagtatca accatttaaa taactagcgt atgaaattct tggggaatat
    45001 aatatggtta ctcttcggag ggattataac aagtgtagaa tatctgatat ccagcctaat
    45061 actaatgata acgatcattg gtataccttt tggcctccag accttaaaat tagcgatact
    45121 ggctttatgg ccttttggca gccgtgtcgt agacgagggg aattccggag gatgcctgtc
    45181 acttatcatg aatgtgatct ggatattcgt cggaggcttt tggatttgcc ttacgcatct
    45241 gggattcggc cttttgctat gtatcacgat catcggcatc cctttcggca tgcaacattt
    45301 taagatggca gctttagcct tggcgccttt cggaaagagc atccaataag ggaacgtctg
    45361 acttttctgt agaagacaga catccggcaa gaatttaggc taggataagg tattatacct
    45421 atttctttct atacctatac attctcgctc cttattctat ttcataaatc acggtatggt
    45481 acgtacagac cacgccttgg tttgtataga tcaagccttg gtctgtagag ttcacggcgt
    45541 gatctgtaga attatactag atattcaaat gaattcatcc gatatctttc aagtattcat
    45601 aaagaaggag ggaagtataa atagcgttca tatacatctc cctcataggg cctaggggcg
    45661 ttatagctcg atctgggaaa ccgaaaccgg agtattcatg aagatagagg ccgcctcaga
    45721 aaacttctct gccgactccg tggtaagaaa acggcaactt cctcccttcg tgagtttacg
    45781 atccatttcc gggtgacgcc ctaaataatc tcgcaaactc tccgctacat gctcgccttg
    45841 cgagaataga gtgatgccgg aaggaagaaa agcacggatc ttatccatca aaaggggata
    45901 gtgagtacat cccaagataa gcgtatcgat ttgcggatct acggataata tatggtcgat
    45961 atgctttttc acgaaataat ccgctcccgg ggaattaaac tcattattct ctaccaaagg
    46021 aacccacatg gggcaagcct cgcctgtcac ttggatatgt gggtacatcc tgccgatctc
    46081 tatcgtataa gaattggacg taatcgtacc gctcgtacct acgataccga tatgtttggt
    46141 acggctgatc gtatccacta actcaactgt aggacggatg actcccaata cacgacgatt
    46201 gggatcccat gtaggcaagt ctttttgttg gatcgtacga agcgctttcg cagatgccgt
    46261 attacaagcc aagatcacca attggcaacc cgactcaaac agacgcaata ccgcctgacg
    46321 ggtaaattga taaacgacct cgaacgaacg ggttccataa ggagaacgtg cgttatcgcc
    46381 cagataaacg taatcataac cgggcatcaa ctgatggatc ttatcgaaaa tcgtaagtcc
    46441 gccataacct gagtcaaaaa gaccgatcgg accgggagtt tgtggaaaca tatcagaaac
    46501 cttcttttat aaagtacaaa gggtgcaatc ctttcggaaa acaccccctc ttttattcta
    46561 tagaataaat tttctcgcta attacaaacc gagtttcgta cgaacaaacg gagttgcgtc
    46621 tactgcgtta gtacccgtat aaagcaaagc tgccggatcg atgatatacg tatatccctt
    46681 ctcctcgcct accttctgga tagcctcgtg caacttctgt tggatcggtt gcaacaattc
    46741 ctgttgtttc ttttgtacgt cttgctgagc tacctgaacg aagttatcca tacgttcttg
    46801 gatatcttga atctcttgca ttcttctcaa cttgatattt tctgtcaatg aatcttgctg
    46861 cgctacgaag tctgaatatt tcttttggta ttcatcttgc atttgcttca attcaactct
    46921 atatttctca ttcaagtctg ccatttgttt ttccatacca gatacctccg gcatagccat
    46981 aaacacctct tgagttttta caaacgcaat tttaacttcc tgagcgatag ctcccaacgg
    47041 gagaatcatc aacaataaaa caataagttt cttcattttt actatataat tactttgtta
    47101 ttaatcaagc tttcacactt ttcatgcata aagcgcacaa atgtaagcat ttattttgaa
    47161 tatcctaact taatcagcac ttcattactg atatcgatct tcggagaagc gaaaataatg
    47221 ctcatagctg aagctcgatc ccaaacaatt tgatatccct tgtcttccga gatttctttc
    47281 accgcattat acacctcgtc ttgaatcggt ttcatcaaac tctcgcgttt cttatataac
    47341 tcaccctcag gaccgaaata tttacgtttc agatcttgcg cctcttgctc tttcttcacg
    47401 atctcttcct cacgtttcgt tttcatctcg gcggagagga ataccagatc gctctgataa
    47461 ttcttataca tattctgagc ttcttgctga atcgcttcca cctcattttg ccatttcttg
    47521 gaaacttggc tcaactgctc attggtcatt tcgtaagccg gaatattctt caatatatat
    47581 tccatgtcga ttaaagcgaa cttctgtgcc atgccggcaa aagaacaaag caacatcaga
    47641 cagctcaatg tgataatctt tttcatactc tctttattta tagttctact ttatgactgc
    47701 aaatataaca gagggtttac ttacagccta ccaatattcg ttaaaagtat ttatttaaat
    47761 gtagagacgg ggcgtgcccc gtctctacat acggaacacg ccccgtctct acatacgaag
    47821 ctatacccga tctatatttt agaattcctg tccgatgata aagtgcaggt tactaccgct
    47881 acgtttacca ttagatccat aattcggctc gtcgaaacca taagcccagt cgagtcccat
    47941 caaaccgatc atcggcaaga atatacggac accgacaccg gcggagcgtt tcaagttaaa
    48001 cggattaaaa ttcttcaaat cagtccaagc gttaccagcc tccacaaata ccaatccgta
    48061 gatcgtagag gaaggctcca gcaagaacgg atatctcaac tccatagcca aacgagaata
    48121 agcgtatcca taagagttgt aaccaccatt accggcgata ctaccattct cataacctct
    48181 caaaccgatc gtttcctgag cataggtact ggagtaacca ctcataccgt caccacccat
    48241 atagaaggtc tcgaacggag acttcttatt tttattataa gtacctaaga agccatactc
    48301 aacacgggtc atcaataccg gcgtacgttt cacggtcaac ggagccaacg gagagaagat
    48361 cttcgctttg aacttccatt tatgatactc gatgaattta tacttatccg gatctgagct
    48421 tgacatcgac gcataatcct taccatcgaa taaagagtaa ggaggcgtag cagctacaga
    48481 caacatgaat tgtgaaccct tacgagtata caacgggtta tcgatagagt tacgttgcaa
    48541 catcaactcc aagttgatat tatggcaatt tccgttatta accaagaaat agtcccaatc
    48601 atgcatcata tacaactgat agttcaacgt cgccatgaac tggaagtagt cgtccggcca
    48661 attcaaacgt ttaccataac cggccgctaa accgaacatc atgatagact tatccgggtc
    48721 gtaagcatac tcataactat tattgtaacc atagttgccg taatagttgc taccatagcc
    48781 ataaccgccc ccataataac cgggataacc atagccatag cccggatagc cataaccata
    48841 accggaattg gtcaagtaat tgctactgat atcggtttgc tttgagaaat aagcgctgac
    48901 agacaatgta ttcggtcgtt taccgccgaa ccaaggatcc atgaaggaga tgctgtaagc
    48961 ctgatagtaa cgcccattcg tctggccgct caaggtcaat gtctgtccct caccttgcgg
    49021 gatgatgccc ttataggttt tcgggtttaa gaagttcttc atagagaagt tcgtaaactt
    49081 caaacttaac ttaccgatca cacccgtctg tccccaacct gcggagaact cgatctggtc
    49141 attcgccttg gaaaccaagt tatactcgat atccacggtt ccattctcag gatcaggcag
    49201 cggcaccgga ttcatgtttt ccgggtcgaa gtgtcccatc tgggccaact cacgaacgga
    49261 acgcatcaaa tcctcgcggc tgaacaacat acccggcttc gtacgcaact cacggcgaac
    49321 gatatcctca tacagacggt cattaccatt aatgataata cggttgatcg tcgcttgcgg
    49381 accctcttgg atacggatct ctaacgagat agagtcattc gctacatcca cctctaccgg
    49441 atcggcgttg aagaacaaat aaccgttatt aaaatagaca ttcgaaacgg catcctcatc
    49501 cgtactcaaa cgttcgttca atttcttttg attatacacc tcgcccggtt tcatacccag
    49561 cacggccatc aaatagtccg tagaatattg cgtattaccc acgaagcgaa tatctttcaa
    49621 atagtatttc tcaccttcat ccactttcaa gaagatatct accttcttct cgttaaagtt
    49681 cgctacgcta tcggacaaca atacggcgtc gcgataacca tgctcgttat atttagcgat
    49741 tatatttttc ttatcgttct catattcctc agtcgtgaac ttcttcgtgc tgaacatctc
    49801 catgatactg gttttccagt cgttcggcaa gctgaacttc tcgttcgtct tcttcatcgc
    49861 cttcttcaac tcccgggcgg tcagtttttc gttaccctca aaatagatac gatggatctt
    49921 ggtcttttca ttcttatcga tattgatatc cacgatcacc tcgccttcat tcgcgggatc
    49981 gtccttttgc tcgatctcga catccacgtt cttaaagcct ttgccatcga agaacttctg
    50041 gatcacgatc ttggcacggt ccatgacgtt cggcgtcacc tggaaacctt tcttcaagcc
    50101 cagcttcgcc tccaagtcct cacgctcgcc ttttttgatc ccgtggtaat tgacttgcga
    50161 gatacgcgga cgctgcttca gctggatctc cagccaaatc tggtcgccct cgatcttcgt
    50221 cgccaagatc ttcacatccg aaaacaagcc atgtttccaa aaacgcttca ctgctgtagt
    50281 gatctcctct cccggtacgg taatctcatc gcctaccgac aagcccgaga agccgatcaa
    50341 cacaaaatca tcataattct tgatacccgt aatctttata tccgcaatct tgtatttctt
    50401 cgcggccaac gagtacgaaa tgaccggcac ttctgccggc gtctcaactt gggtagtgtc
    50461 tatttcttgg gcaaacgcac cgcaagcgaa acccaagcaa ataaaaaaca gcactattct
    50521 tttgtacata taacagctat tgtttataag attaattgct cacttgtctt accgaaacga
    50581 cgctcacgtt gctggtaata caatatagcc tcatacaact cttcttctct gaaatccggc
    50641 caaaacacat ccgtaaagaa gaattcagca tatgacaact gccatagcaa gaagttactg
    50701 atgcgtttct ctcctccggt ccgtatcaaa agatcgggat cggggatatt tttggtcgtc
    50761 aagtggtccg agaccatagc ctcggttata tcattggggt ttattttctg ttccaagacc
    50821 tcttgggcga gttgcctagc cgctctggtg atctcccacc gggaagagta actaagcgcc
    50881 agaacaagtg tggttcccgt attcgccgaa gtcgtatcga tacattcttg caatgtatta
    50941 taagcatcct cacgcaagcg ggaaaggtcg cctatggcgg taaggcgaac gtttttcttc
    51001 atcatgtccg gagtctcccg gtgaatggcg gagaccagca agctcatcag cgcttggacc
    51061 tcttcttccg gacgattcca gttctcggta gagaaagtgt acaacgtcag atatttcaat
    51121 ccgagttgag tgaccgcatc cataatctta cggaccgaaa cgacgccttc ctgatgcccg
    51181 aagctacggt ctttcccctt cgccttggcc caacgtccgt tcccgtccat aataattgcc
    51241 acgtgccgtg gcaagcgatt cttgtctatt ttctcaatca acgacatttt ttatcttact
    51301 aatattcact tatatttttc gcattgttac aagtacggca cctcgggccg aaatcccatg
    51361 taacagacaa caacaagaaa gagtaccaat ctttattctt aagagcgcta cccttaacac
    51421 catacggatc gtccaacatg tcctttccct ctaggccatc gccaaataac ttacgaaacg
    51481 agaactcgca ccctaaatta aggcggttct tgatcttata tttcatgccc acgcctaaag
    51541 gaatattcgg gctggcgaaa gtcttcccgc cacccggagc caccgtcagc cctatgccca
    51601 ccaagacata aggagagaaa cgcttcgccc ccgcatagtc gaacttatcg ctatacggga
    51661 aaaagttgaa ctctgcctgt ccccccaact ccatgatact acggttgaaa gaggtttggg
    51721 cattattcgg aaaaacgttc tccatacctt cggtcttacc ggaaacctgt ccccacatca
    51781 agttggcttt taaggcccaa cgaaagttga tgttataccg gaacacggct cccaccgccg
    51841 gattcattcc tttaaatatc gtattcttgt tggcgtcgcc catataaaag gcgccaccag
    51901 ccataccacc gatctcgtac ttatattcct gcgcccaaag cgtaggaatc gtacccgcca
    51961 ataggatgat tatgagaagc cgctgaaaaa aagttgaagt cataagcctt gctgttatat
    52021 ataccacact tctttttcta acgctaaaag cctcataaaa ttatacatct cctatcgaac
    52081 ttttctattc cttcgggatc aaacgattga tacggcctct ccaaagttgg ttcaagtcat
    52141 tggaaccagt gctggtcttt cctccgaaaa tgttcacgaa attctcttta tccacaataa
    52201 ttgaggaaaa gcctctcgcc gcatagtcgg tcggtaacac caccatcgag tcgatcaacg
    52261 accaagaaat accataatct atcgattgat acatatcttt caatgccttg ttcgaagcgt
    52321 cgatacctcc gatcaagaaa aacttatcgt cataattcgt gatcatcgct ccctcacgct
    52381 tcgtgaagtt tgcgtcaccg gaagccatca acgcccaaga gataccatcc atggtagccc
    52441 aagtcgtatt aaccacttgg ttgtccacgg tacgtccgct ggcggtcatc aagtactcat
    52501 gatacattgc ggcatattgg agattgctaa atccggtaac agggaatccg ctaggcaccg
    52561 catctccggc gatccactcc atggattcgt tcatcgcata gaacgctagc tttccttcct
    52621 gatccacgat cgtagctaag gcggaaggct gtttcgtgcc ctgcttcacg ctacccaaaa
    52681 cgtatttcac ggaaggggcg ttctctacag cgctccaagt caagccatcc tcggatctat
    52741 ataaagtgcc atttgtagcc ggcacatata aagcattgtt atactcagta atctgggaga
    52801 tcaaaagccc atcggaaggc agaccggtca aggataatga ctgccagccc ttaggcgcgc
    52861 ttaccggagc gtaatataat tggtaaggtt taccggactc ggcgggtttc acatacataa
    52921 agtaattctc cgatccatta taatcgtagg ttaccacctt ctgatccttc acggtaatgc
    52981 caatcatagg attcgcgtac atactccaaa ccatagagtc cggaaccact tgatggatat
    53041 tcacttgcgc catatagact tttgtcgtga cttggtcata cgcatgaacc acgaacttta
    53101 ccggagcgga gaaatcgatg gaatccgaca aactacttaa ataataagtg gaatcgggat
    53161 aagcctcggg actagcctcc acgccaccta tcactgaaga attagcgaac ccaatcttac
    53221 aaaccacttt ctcgatcttc gtaccaaaag gtaaagagtc tatattaaaa atccgtcccg
    53281 ttagctggtc tatcgtaaac ttcacagtat ccaaccccga cacagaatca tgacttaatg
    53341 aaaaagtatg tatctggcaa ttcttaatag cttctacacc aacgatttca tctgacttca
    53401 aacaagaaga cagcactaac gcaaaacaac ctgttataaa tagtactaat ttatttttca
    53461 tcaaaaacat aagtttgtcg catataaagg cacaaaagta gaaacatttt ttgctttcac
    53521 cctaatacct gctaatattt ataatatttt agttgattat atgagcctta aaattcatag
    53581 ttatgatttt tcgaactcat cgttatgatt taaaatttca tagttatgat ttttaatgct
    53641 cataacagaa cgtccggaga tgccgctaac agcctccttt ccaagcatcg gcgcatgcac
    53701 cccttgatac agacgaaccg gggccgtttc caccctcgcc tcgtcccata catccgcttc
    53761 cacaaaagaa ttaatcagct gagtcccacc ttccaccaat aaggaatcca acttccggac
    53821 agcaagatga tctagcactt gccggatcac cggaccctcg aaatctatcc ggatatactc
    53881 cacgttctct cggttttcca cttccttctc cgtaaatatt aatgtacgtg aggaaccatt
    53941 cagcaaccga taagaatcgg gaataacgag ccgacgatcc aatacgaccc taaccggaga
    54001 attaccggac caatggcgca cgttcaatga tggattgtcc aataaagcag tccgtgtacc
    54061 gaccatgata gccgccacct ccgagcgaag tttatgcacc aagcgggaag tctccggaga
    54121 agacaaaacc gtgaccggct ccgacacgtc catacgtaaa cggtcgataa acccatcctc
    54181 actctgcgcc catttcaaga taatataagg acggcctttc gtttgtagcg tcataaacgc
    54241 cttgttcaac gcacgggctt cttcctccat cacgcctgtg actacctcga caccggcctc
    54301 acgcaacatc cgcacacctc gccccgacac ctcgggaaaa ggatccaagc aaccgaccac
    54361 cacccgtgga atccctttcc tgataatcaa ctcggcgcaa ggaggcgttt tcccataatg
    54421 agagcaaggc tccagactca cataaatcgt actgtctgtc aacaaagact cgtctttcac
    54481 ggaagcgata gcattcacct ctgcatgcgc ctccccacat ttcctgtgaa atccctcacc
    54541 gataatacgg cccttatgca caaccaccgc accaaccatc ggattcggac tgacatttcc
    54601 cctccctcct ttagccaact cgatgcaacg agccatgtat ttctcttcaa cctctatcat
    54661 aatctttgca tataaacggt ttttacacta cttttgcgat aaaacaagag taagatatga
    54721 ctgagaccat cgcctacatc cgaaattccc tcaaagatat ttatcctccc ggcgaagccc
    54781 aagcgctcgt ccggctcatc atggaacgtg tttgcggcct ttctacccat caactcctgt
    54841 taggcaaagg taaagaatta tctgatacgg agaaatttaa aatcaaggag attgtagaag
    54901 gactgcgttt atacaagccc atacaatact tattaggcat agcggatttt tacgggatgg
    54961 agtttaaggt gacgccggac gtattgattc cccgcccgga aaccgccgag ttggtcgagc
    55021 ggatcatcac ggactaccga ggccaagccc ctcgtatatt agatattggt acgggaagcg
    55081 gctgtatcgc tatttccttg gcgaaacatc ttccgaaggc tgaggtagcg gcggtagata
    55141 tatcgcccga ggcacttgcc gtggccgagg agaacgcccg actgaatcaa gtttccgtat
    55201 cttttctcga attggatatc ctttccgaag gttatcccag tttcatgcaa ggaaaactaa
    55261 agtttcacgt agaagaaaca aaagtttcac gtaaggaaaa caaaagtttc acgtacatga
    55321 aaccaaaatc ccatacggaa gaaaccgctg tttctcctat aggcaacttc aattgcatcg
    55381 tcagcaaccc tccttatata atgaataagg agaaagcgac catggaagcg aacgttttgg
    55441 agaacgagcc tcacctggcc ttgtttgttc ccgatgacga tccgcttctc ttttaccggg
    55501 ccatcgcccg cttcggacaa aggcatttgg tggaaggcgg gcatctttac ttcgagatca
    55561 acgccctttg cggaaaagag accgtagcga tgctacgtca agagaattac accgaagtcg
    55621 aattaataca agatttatac ggaaaagacc gtatcgtaaa agcaaaaata tgaaagagat
    55681 aaccgaaccc gagatgttgc accgggcagc cgcctattgc tccgccgccg aacgctgcat
    55741 acaagacgta cagaaaaaga tcgatgccgc cggacttccc cccgacgcct ccgagcgtat
    55801 catcgcccgc ttgctgaaag agcggtttat cgacgaatcc cgttacaccc gtttcttcgt
    55861 gaacgataag ctacgattca ataaatgggg acgggtaaaa ataggctacg agctttataa
    55921 gaaaaacatc ccctccccga tccgggaaga atcgctcgcc gccatcgacg agggagaata
    55981 ccgctccatc ttactcgatt tactaaaaag caaaaagaaa tcgacaaaag gaaaagacga
    56041 gcgggaccta ttcaacaagt tactccgttt cgccgccgga cgaggtttcg aaagccggat
    56101 cacgttggat tgcctaagcc aattattcaa aggaatagac tgcgaggatt atgccgacga
    56161 catggaataa tctgctcaac ctgtttttcc ccaacttatg taaaatatgt aaacgaccac
    56221 tcgtcgaggg agaagaacaa atttgcctga aatgcctatg cgacctgccg cacacgggat
    56281 atcatcaaca ggcgaacaac cccgtcgagc aactttttat cggaaagaac cggatcgaat
    56341 atgccaccgc ttatctacga tacgagaaag gcggaaaagt acaaagcctg atccactcgc
    56401 tcaaatacca tgataataaa gagttgggct atctactcgg acggcagata gcgagagagc
    56461 tccaagcgga tcacagcccg atatgtaccg tagacctcct tatccccgtt cccctgcatc
    56521 cccgcaaaaa acggcaaaga ggttacaacc agtccgaatg gatcgcctcc ggcatccgtt
    56581 ccatatggga tatccccatc gatacgcaaa gtctagcccg caccacccac acaagtaccc
    56641 aaactcgtaa ggccatttac gaccgttggt taaatgtatg ttctattttt aatgtcattc
    56701 atccggaaag cttaaaaaac aaacatatcc tgctcataga cgacgtgatc acaaccggag
    56761 ccacgatttc cgcttgcgca aaggctttat cagggattcc gggcatacgc atcagcattt
    56821 tagccctgtc tgtcgcataa atattaataa aaaattaacg tacgatattc aaggtaatgt
    56881 cattcagttt atctattttt gcagactgat ataaatatag gattgtatga aaacactgga
    56941 aagtttagta gcagaaaaat tattaaagat taaagccgta aagttgcaac cggccaatcc
    57001 gtttacttgg gcatccggct ggaaatctcc gatctacaat gacaaccgaa agactctttc
    57061 ttatccggtc gttcgtagct tcattaaatt ggagttggct cgtgtgatta gtgaaaaatt
    57121 cgagaacgta gatgccattg ccggtgttgc tacaggcgca atcgctcaag gtgctttagt
    57181 agccgattta ttaggattgc cattcgtata catccgctct acgccaaaag atcatggatt
    57241 ggaaaacctt atcgagggag aattgaaacc gggttctaaa gtagtgatca tcgaggattt
    57301 ggtatctacc ggaggtagta gcttgaaagc cgtacaggcc gtacgtaact ttggttgcga
    57361 tgtagcgggt atggtagcta tctttaccta tggattccct gtagcggaag ccgctttcaa
    57421 agacgctaaa gtaacattga ctacattgag taactacgac gcagtcttgg aagaagctgt
    57481 ccgtacgcat tacatcgatg agtctgagat cgcggttctt caggaatggc gtaaagatcc
    57541 ggctaactgg gacccgaaat aagtaataaa caaaaagaca ctcaatgact gaagaatttg
    57601 tgagtgaggt caaacagatc ccacacaatg atgaacgtat cttcacgatg ttgtccgatc
    57661 tttccaactt ggaacgtatc aaggatcgca tcccgcaaga taaaataaaa aattttgagt
    57721 tcgacagcga tacctgtagt ttcgctgtcg atcccgttgg taagattacc ttccagatcg
    57781 tagaaagaga gccgaataaa ttaatcaagt tcacgacgac caactctcct gttccccttt
    57841 tcttgtggat acaattgaaa caggtggccg aggacgacac acggttaaaa atcacggttc
    57901 gtgccgatct gaatccgttc ttgaaaccaa tggtatcgaa acctttgcaa gaggctgtgg
    57961 ataaaatctc gaccgttatc gcctccttgc cttattaatt cctttttcat tatggctcag
    58021 aaactttggg aaaaaaatgt acaggtagat catgaagtag atatattcac ggtaggtaag
    58081 gaccgtgaga tggatcttta cctcgctaaa tatgacgtat taggctctat ggcgcatatc
    58141 acgatgctgg aaagtatcgg tttgttgact aaagaggaac taaacgtctt attagcagaa
    58201 ttacggaata tatacgccgt agcggatcgt ggagaattca tcatcgagga aggcatcgag
    58261 gatgtgcact cgcaagtgga actcatgctt acacgtcgtt tgggcgatat gggcaagaag
    58321 atccatagcg ggcgttcccg taatgatcag gtcttattgg atctgaagct tttcacccgt
    58381 tcgcaaatac aagaattggt tgagttggtt tccggcttgt tcgacgtttt gatctcccag
    58441 agtaaccggt acaaggatgt actgcttccc ggatatacgc atctacaggt agctatgccc
    58501 tcttcgttcg gactttggtt cggcgcttat gcggagagct tggtagatga tttgcaactt
    58561 atgcaagccg cataccgtat ttgcaaccgt aacccgctgg gttccgccgc cggatatggt
    58621 tcatccttcc cgctaaaccg ccagatgact acggatttat taggtttcga ctcgctggac
    58681 tacaatgtgg tatacgccca gatgggacgt ggcaagatgg aacgcaccgt agctttcgct
    58741 atggcgggta tcgccgctac gctttccaag ttagcgttcg acgcttgtat gttcaatagc
    58801 cagaactttg gcttcatcaa actgccggat cagttcacga ccggctccag tatcatgccg
    58861 cataagaaga atccggatgt atttgagttg acacgtgcca aatgcaataa gcttcaaggc
    58921 ttgcctcagc aaatcatctt gatcagcaat aatcttcctt ccggttactt ccgggatctc
    58981 cagatcatca aggaagtctt cctaccggct ttcgacgagc tgaaggattg cttacgcatg
    59041 gtaactcata tgatgcgtga ggtgaaagtg aacgagcata tattggacga tgataaatat
    59101 tctctattgt ttagcgtgga agaagtgaac cgccgtgtct tggccggaat gcctttccgt
    59161 gacgcttata agcaagtagg tttggatatc gaggccggta aattcgttcc ttcgaagagc
    59221 gttaaccata cacacgaagg cagtatcggt aatctatgta acgaaccaat cgccaccatg
    59281 atgcgtagcg tgataggttc tttctctttc gaacggatga acgaggctga aaagaaattg
    59341 atccatggat aagataagac ggatatttcc acttttgatc ttgtttacgc tattatcttg
    59401 cgcagatacg atagagactc gtattcccta tcgtgtggtc tatctggaac tagatctgac
    59461 ttatcaagat aaagcgttga atgcaataca ggcttataag atctacacct ctaaagatgt
    59521 agaccaagct ggcgagcaaa cagggtttgg aggcgtattg gtctatcatg gattgtccag
    59581 taacggaacc ggtgcattct ttgcgttcga tgcagcttgt cctcatgagg catccactaa
    59641 tgtcatcgta gatgtggacg aatctgccgt atacgccatt tgtccgaaat gcggtagtaa
    59701 atttgaactt ttaaacggta tcggcaatcc ggtggaaggg ccttgcgctg aggagaaaca
    59761 agccctcaaa caatatgtcg tcgatacaaa cggtaataaa atttacatcc ataattaaat
    59821 ttttcaccga aaatgtttgg tagtataaat atttgtacta cctttgcact cgcaaaagag
    59881 aaacaaacaa tgcggaagta gctcagttgg tagagcataa ccttgccaag gttagggtcg
    59941 cgggttcgag tcccgtcttc cgctcaactc ttagagaaga ggtggatgct cgaatggtgg
    60001 aatcggtaga cacgaaggac ttaaaatcct ttggccattg cggctgtgcg ggttcaagtc
    60061 ccgcttcgag tacgatctaa tttaattgcg gaagtagctc agttggtaga gcataacctt
    60121 gccaaggtta gggtcgcggg ttcgagtccc gtcttccgct cgcttccaaa aggcctcgct
    60181 gttcgaaaga atagcggggc tttttatttc taaaatataa tcgtatcttt atcttcaatt
    60241 aaagtgaggg ttatggaatt acgtacagcg aatgttaccc gatatatcat gcctctgcgg
    60301 gaaggcggat cattgcctgc tttagcggag gcggacgatg agtttaaata tgtcgttaag
    60361 ttccggggag ccggacatgg gacaaaagcc ttgatagccg agttgatcgg aggtgagatc
    60421 gctcgttgct tgggtttcca tgtaccggaa ttggtcttcc tgaatcttga cgaggctttc
    60481 gggcggtcgg aaggtgacga ggagatacaa gacttactac aagcaagtca agggctcaat
    60541 ctgggattac attttttatc cggagccttg actttcgatc cggtagtcaa tcgtgtagat
    60601 cccaaactcg cctcacaagt cgtatggctc gatgctcttt tgacaaatat agaccgcacg
    60661 gtccggaata cgaatatgtt gatatggaat aatgaacttt ggctcatcga tcatggagct
    60721 tccttatttt tccatttctc atgggtaaat tggcaaaaac atgcgatcgg ccctttcatc
    60781 catatcaagg atcatgtatt attgccacaa gcgacgctgc tggaggaagt agacaaggat
    60841 ttcaaacgta tcttaacgga agagaaaatt cgtgagatcg taggtctagt acccggcgat
    60901 tggttgcatt ggaacgatag tcccggtacg cctcaagaga tacgtgatgt atatatccgg
    60961 ttcttaattg accgaatcgc ccattctgac acgtttataa atgaagttcg acatgcaaga
    61021 caaacactta tatgaatatg ccgtaatccg tatcgtaccg aaaatcgaac gggaggagtt
    61081 tatcaatgta ggccttatca tgttctgtaa acggcctaaa ttcatcaagg ctcgctatca
    61141 tgtagacgag aagaaacttc gtctgttcac atcagatata gataaagaat ctttgtgcgc
    61201 caatctccac gttttcgata agatatgttc cggcgccaag gatggaggcc ctatagctag
    61261 cctagatatt ccagagcgct ttcgttggct taccgccata agaagtgcct ctatccaaac
    61321 ctcacgtcca catcccggtt tttccaacga tctagaacag acatttgaga gattatttca
    61381 agaattagtc ttatagataa taaacataaa tctccgtatc acgataaaag aaaaaagacg
    61441 gatcgtttaa acaacccgtc tttccttatt aaattaatag atattatact tttcctttta
    61501 agtccgcatc catagcggcg gcggccttac gaccgtctcc catcgccaga atcacggtag
    61561 ctccaccacg aacgatgtca ccaccggcat acacatcgcc taaagtggaa cgcatactgt
    61621 cttcctccac tacgatcgta cccttcttgc tcacctccaa gcctccaaag gcacggggta
    61681 ttaatggatt cggagataca ccgacgctaa cgatcacctc atccacatca attgtttcga
    61741 tagcgccctc gataggtacc ggacgacggc gaccagaggc atccggctcg cccaattcca
    61801 tcttctgcaa acgcatctgt ttcacacggc ctctttcatc acctatatat tcaatcggat
    61861 tatgaagcgt caagaactcc acaccttctt ccttcgcatg tttcacctct tccagacggg
    61921 caggcatctc ctcctcgcta cgacggtaga cgatcatagc acgctcagca cccagacgac
    61981 gagcggtacg gacagagtcc atagcggtat ttcctccacc gatcacggcc accttctttc
    62041 cttgtagcac cggcgtatca ctttccggat tcgccgcatc cattaagttt acacgggtca
    62101 aatactcgtt ggacgacatc acgcccacaa agttctcacc cggaatgttc ataaagttag
    62161 gcagaccggc gccacttgcc acaaacacgc ccttaaagcc atccgcatgc aaatcatcat
    62221 aactgatcgt cttgcccacg atacaatctt tctcaaactg tacgcccatc ttccgaaggc
    62281 catcaatctc cacgtccacg atcttattcg gtaggcggaa ctccgggata ccatatttca
    62341 atacaccacc gatctcatgc aatgcctcga acacagtcac atcatatcca cgcttcgcca
    62401 tatctccggc aaaagacaat ccggcaggac cggaacctac cacggcaatc ttgataccgt
    62461 tcttctccgc gatctccgga accgagatat taccgctctc acgttcgtaa tcagcggcga
    62521 aacgctccaa gtagccaatg gcaaccgctt ccttacccat tttcaaatgg atgcacttgc
    62581 tctcgcattg tttctcctgc ggacagacac gaccgcaaac agcgggcagg gcacttgtct
    62641 ctttcaaggt cttagcggcc tccaagaatt ccccacgctc gatattcttg ataaaagtag
    62701 gtatattgat atttaccgga catccctgca tacaagtagg attcggacaa tccaaacagc
    62761 gctcggcctc ttgcatggcc tgttcttttg tcaagcctaa gttaacttcc tccaaacggg
    62821 tacgactccg gtattccggg tccaactcgt tcatcttcac acgggggata tccgcacgtt
    62881 ctttattttt cttgcttttg cgaagtgcct cccgccaagg ttcggcacga cgagcagcga
    62941 ttaattcttc tgttgtcatg attcaattac gtggtttcgt tatttcttct ctatatcctt
    63001 ataagcgccg agacgcatga tcatctcatc aaaatccact tgatgagcat cgaactccgg
    63061 tccgtccaca caaacgaact tggtcttccc gcctaccgtg atacggcaag caccacacat
    63121 acccgttccg tccaccatga tcgtattcaa ggaagctacg gtaggaatct cgtatttctt
    63181 tgtaagagcg gaaacgaatt tcatcataat agccggaccg atcgtaacgc ataaatccac
    63241 cctctcccgg ttgatcacgc tctccacgcc attcgtcacc aagcctttcg taccatacga
    63301 tccgtcatcg gtcatgataa ttacctcatc cgagttttgg cgcatctgct cctcaaggat
    63361 caccaagtcc ttggtacggg ccgccaatac gacgatcaca cggtttcccg ccttatggaa
    63421 agcctccacg atcggcaaca acggagcgac acctacgcca ccaccggcac aaacaaccgt
    63481 tccaaccttc tcgatatggg tagcctgccc taacggaccc accacatccg tgatatagtc
    63541 accctcgttc aattcacaga tcttacggga tgagccgcct accgcttgga tcaccaaggt
    63601 gatggtacct ttctcggtat ccgccccggc aatggtaaga ggtatacgtt cgcctttatc
    63661 gccaaccttc acgatcacga agtgaccggc cttgcgggag cgggcgatca aaggagcctc
    63721 gacttccagc ttcaccacgt tggctgagaa atgttcttta cttacaatct tattcattat
    63781 aatcgctact gttgatagtt tgtcttgttt tgctggcaaa aataagataa aaaagtgaat
    63841 atagccctat tttccttaac aaaaggcttt attcaaacaa accttcatca cgcactaaca
    63901 tcaaaatagc ggaatgaggg acaatcaaga acttctcgtc attaaaattg atctcgtaag
    63961 cggcgttctg caaatagaca gccaaatcac cttcacgggc ttgaagcggc aagtattgca
    64021 cctcctcccc tttctttttc tcccagacct catgctcctc agattgagaa ggcaacggat
    64081 atccgggccc cgtctttatg atataacccg cttgtatctt ctccccttgt tgaaccgagg
    64141 gaggcagata caatccggtc ttcgtctggc tctgtggatt cttaggctta atcaatactt
    64201 tatcgcctat catcaggaat ttatcgatgt ctttttgatc tatggatagt tgcatgatta
    64261 taagatgtta aatttttatt tcgcgaactt acggaaagtt taccgaacaa aaaaccctgt
    64321 tcgttgaata aatccgctcg ttcacagatt atattttcct aagtttttcc cttgatttac
    64381 atttacaccg ttagaacttg tgaaagccat aacaatccgg ttcatcatac agaccggcag
    64441 aataggtaaa cattaaggaa aagggcactt tcgggtgccc tttctcattt atccccatca
    64501 gaaaacaatc ggattctatc aaaagttgtt caccgataaa aaacacgatt tcacagaata
    64561 aatccgccca ttcactgact tttattgctc agactctaaa caaactttaa tattgaacct
    64621 agtttactat actttattaa cctattttat tatgaaacac agacatgcga tctttagaag
    64681 caggctggga ctagctttat gctttatgtt ggcaggcggt gctatcatac cgcaaagttc
    64741 cgtattaaaa gcggaaacct ccgttacgca acaatcccgg aaaataacgg gtacgatcac
    64801 cgacgctaaa ggagagcccc tattaggtgt taacgtagtc gtaaagggta ccacgaacgg
    64861 aacgatcacc gatctggatg gtaaatacgt attagaagta gagccgaatg ccattctggt
    64921 catctcttac atcgggtacg taactcaaca aacacctgca agcgggaacg tcatgaacat
    64981 taccttaaag gaagacaccc aaaatctaga cgaggtagtc gttgtcggtt acggtaccca
    65041 acagaaaaag gacatcacag gttccgtagc ggttatcgat actgaagagc tattggcgtc
    65101 ttccggttct tccgccacac aacagttgca aggtaaagcg gcgggcgtaa acatcggtac
    65161 ctctggtgct cccggttcag ccacgatggt acgcatccga ggtattaatt ccatcaatga
    65221 caacggacct ttgtatgtta tcgatggtgt atccactcgt gaccaagacc taagctctat
    65281 caatcccaat gacatcgaga gtatgcaagt attgaaagac gcctcctccg cagcgatcta
    65341 cggagcgcaa gcagcgaatg gcgtcatttt gatcacgacc aagaaaggga caaaaacggg
    65401 acagccgaga ttaacctatg acggatatta cggtttctct aaaacaggta aacgctatga
    65461 cgtcttaaac gcttatgacc gtattgatgt cgaatggcaa gcctcgaaaa acaatctgga
    65521 cctaacagga gccagcgcca atggagaatt accttaccac cagcaattcg gaagcacttc
    65581 cgactcttgg gttaatcatc tacccaatta catgaccgta accggcgccg gtggtagcac
    65641 ctccatcgat cctagcgatt acgatcaagc gaacaacgta gtctatgcgc ccgtaggcga
    65701 tacgaactgg tgggatgaaa tcagccaact cggttggatg caaaatcacc agttgtcctt
    65761 gtctggaggt accgataaag ggcaatacac catgagcatg aactatttcg accagcaagg
    65821 taccgctatc gaatcttatt tcacacgcta tcaagcacgt gctaattcat cgtataacgt
    65881 ccgcccatgg ttgcgattcg gagagaacca aacttatagt tttagcaaaa acaacggact
    65941 tagcttctca ggtacagagt ccaacatcta ctcatggact tatcgggcct ctccttatgt
    66001 accggtttat gactatgcgg gcaattatgc aggctcctta ttcgccggga ccggcaattt
    66061 ccagaatcct gtagctattc gtgaaagaaa taaggataat tatgccacta cccaacgtgt
    66121 atttggcaac gtgtatggag aagcagacct atggaccggg ctgactttta aaacaaactt
    66181 cggtatcgat tatcgtaatg attattctta ctcgatgacc aagaacaacc cggagttctc
    66241 cgagtccggt agccaaaata atttctacga aagtaattac ttcaattatc gttgggtttg
    66301 gaccaatacg ctatctttca gccggacatt caatgagatc cattccttga acatcttatt
    66361 gggaacagag gctattcggg atggtttagg cagatccctc aacgcacgta gatataacta
    66421 tttattcgaa gacaatacca atacatacac cttggatatg ggcgagaaca atagccaacg
    66481 taccaactct tccacttaca atggagaatt cgcgctattt ggtatgtttg cccgtgcaga
    66541 ctatggatat aaggataagt atctattaac tggtattatc cgccgggacg gtgtttcccg
    66601 tttctcggaa agtaatcgtt acggagtctt tccttctatc tccgccggtt ggcgtatgtc
    66661 agaggaggca tttatggaac caagccgaga ttggctggac gacttaaaga tacgagccgg
    66721 ttacggcgtc acgggtaact cagagattcc tgtcgcgact aatttcgcca atttgttcac
    66781 gaccagcacc tcctatacga attacgacat gaccggagcg aacaatagcg agacaaccgg
    66841 attccgcctc agtacctacg gtaacactga tacgaaatgg gaaatgacca agatggtcaa
    66901 cttgggtctg gacgcgacct tcctgaatgg taaattcagc ggttcattcg aatggtatac
    66961 gaagaagaca tccaatatgt tgatacaagc ggcctacacc tcgatggccg gagaatccgg
    67021 aagcccttat atcaacttcg gagatataaa gaacaccggt ttcgacttca tgtttaatta
    67081 ccgtgaccga aaaggagact gggcatggga tctatccttg aatttatccc attataaaaa
    67141 tgaggtcttg aaactcgcgg aagctgacga ttattctcta tgggctagcg gtacgcgcat
    67201 cgaaggatac gtaacccgta cgacaaaagg acatgccgtg tctgaattct gggggttgaa
    67261 gcaaaatggt ttttatgagt ccgtagccga tgttatggca accaagccat ttggacaaag
    67321 tgatatcaca gaggcagacg ctgccgctta tgtcggccgc ttccgtttcg aggacttgaa
    67381 cggagacggc aaattggatg atagcgaccg gacctttatc ggctctcctc atccggactt
    67441 aaccggaggc ctcaacgcca cgttaacatg gaaaaactgg gactttacta tgttctggaa
    67501 cttctctatc ggcaatgact tatataataa cacaaaatat tttaccgatt tctggacttt
    67561 caacggtaat aaatcctcac gcctcagaga tcaatcatgg acattgaatg gcgataacag
    67621 taatgctatc cttcctatgc tgaatacgga agataactat tccggagctt attctagctc
    67681 ttattacgta gaagacgctt ccttcttacg cctgaaaaat ctcgtattgg gatattcctt
    67741 gcctaaggaa ttactcaaga aggctggtat ccagaatctt cgcctgtatt tacaagccga
    67801 gaatatcctt acgatcaccg gatatacagg cttagaccca gagtttacca acgcttattt
    67861 acggcaaagc gattctgaca ccgacggagc cggacgtgta gacttaaaaa gaggagtcga
    67921 tatgggaggc tggcctacaa ctatgcgatt cttattgggc gtgaatttta ctttctaaat
    67981 ccatttacta taaaaacgac tattatgaga cataaaatat taatagtaag cgcagctgct
    68041 ttatttacct tgagttcttg cggtgaagat ttcctgtata aagctcctca aggcagtatt
    68101 gaccaagaag cattaacaaa cgcagaaggg gttgagttat tggtggtcaa cgcttatgcc
    68161 ggtttgaccc ggccgaccgg atatgacaat atgttcaact gggtattcgg cggtgtatac
    68221 ggaggtgacg ccaataaagg ctccgaatcc aatgaccaat ccgtattgaa ctccgtagag
    68281 acgtatgctg tcaccgccac aaacgattat ttactgaata agtggaaaga cgcgtattat
    68341 ggagcacaac gttgcaactt agcgctcaat gtgatgaaag aagcggcaga tatggacgag
    68401 acgaccaagg ccaaccggac cgcggagctg aaattcttac gtgccctatt catgttcgaa
    68461 ggggtaaaga ttttcggacc gaccggcatg ccctatatcg atgagacgat cgccgctgaa
    68521 gaaaacgatc cgaaagttca taacggtacg gatatctatc ctaatatttt agcagacgta
    68581 gaagcggcca ttgaaggatt gcccgaaaaa cagaccgaag tggcacgtcc tacgaaaaca
    68641 gcggcaaaag cgttaaaggc taaaatactg atgcagcaag gtgatatggc agccgccaaa
    68701 cccatcttgg ccgatattat cgcaaacgga ttaagtccta aaggagagag attggcctta
    68761 caagatgatc tggacgcaaa ttttaacgca actaccgaaa atgggaaaga gtctatcttt
    68821 gaggtacaat tctctgtcgg agccaataat aacgggaatt acggattttt actgaattat
    68881 cctcataaca caggccccgg tggatgttgc ggattttatc aaccctctta cgaattggta
    68941 aactcattcc aagtagacga aaatgggctt ccttatcttg agggagagta cagaaataaa
    69001 aaatccgtga cagaacgtgt taccgattat gattacatct ctaagaatga taagacgatc
    69061 gccgtagacc ctcgtctaga tttcgccgta ggacgtatgg agattcctta taaagattgg
    69121 ggattgcccg ctaatgattg ggtacgaaat gtaagcagcg gtggggtatt cctacccaaa
    69181 aagcatgtct atagcaaagc ggaacaggat gccggattag ctggctccac ctattcatcc
    69241 ggctgggctc ccggttctgc catgaattta caatatctat gcttacgtga ttgtaaattg
    69301 ttatatgcgg aatgcctagc gaacgacgga gaattaagtg ccgccatgca gcaagtaaac
    69361 gatatccgtg aacgtgcagc caaaccggac aatatcattt atttggaaga cggaacgcct
    69421 gccgccaatt atttggtgaa accttatcca tccagtcacg ccgcattcag caacaaggaa
    69481 acttgtatca aggcgattca tatggaacgt aagctggaac ttgcgatgga aggacaacga
    69541 tttttcgatc tggttcgttg gggaggtgat tatatgaaca aggaattgac ggcatatata
    69601 aattatgaga agcaatacct aactaaattc tatggtgtat ctgctccaat cgcttctaag
    69661 acgatattcc cgattcccga gacagagatc cagaccgcag gaaacgatga gaacggccaa
    69721 gcttatctgg tacaaaatga tgcttggaaa tagtccaatc tcatccttct tataaacaga
    69781 aaggcgggct tcccgaaaga aagtccgcct tcacgattct ttgtatctac attaaataga
    69841 acgtcccttg aacacattcg actcgctcga aggatagaga tttcccgtaa aggatatacg
    69901 gttgctatta aagttaggtg ataccgtggc agtacattta ttcgtacctt tcgccatacg
    69961 gaacgtaacc ctagcggata ccgctacacc ctgcacattc atctcgtaca taacgtttcc
    70021 ttttttgtca gtcttcatct gtacaccgga agttgttcca tcaaccgtta tacctcctat
    70081 tccgttagga ccggccgccg gagtattaaa cgctaactga atggtagcct tctcaccctt
    70141 caccgaaacg aagttcgtgt tcggagtaac ataaacaaaa ctaccgcgct taaactctat
    70201 acgatccgct tccaatacga aatccttatt cttcaaagct tgcaccgctt gttcaaacaa
    70261 tgcgttagcc tcggcttcct ccgcagcttt cttcgctgcc ttctctgctt tctttgcttc
    70321 tttctcagcc tgcttcgcag ctttctccgc tgacttgtcc tgctgtgcca tcatcgaccc
    70381 tgcaccaaat aataaaacgg cgagcaataa tacaatcttc ttcatattaa ctcattttta
    70441 aaggtttgtc tataaaagta cttttataca tacaataaaa atacaattaa catcgacata
    70501 agttcatctt taacccttat ttttcacgtt tttaacatga taccataaaa agccccatgc
    70561 ggttaccgcc gcaatgaaat cggagaaagg ttgcgctagc caaacgccat ccaatcccca
    70621 gatcggagga aatagcagga tagccggtat caggaataaa acctgccgac ttagactcag
    70681 aaacatcgct ttccatgcga caccgatact ttgaaaaaac tggctgatcg taatctggga
    70741 accgacaacg aaaaagacca gcatcgtcag acgtaatcca ttgtccgtaa tcgacaccaa
    70801 ttcggcatcc gtcgagaata cgctaacgat cagtctaggg aataataaac tgacgataca
    70861 tcctacccct gtaatcaagg tcgatactat aatagacaac cgcaaggtag ccaatacccg
    70921 gtcatgatgc ccagcgccat gattaaaccc gacaatcggt tgcatccctt gggcgatacc
    70981 gataatcaac ataaccagca gcatggcgat actggaaata ataccgctgg caccaatcgc
    71041 caaatcgcct ccattctctt tcaacgcatg gttcatgatc accacaacca cactgcccgc
    71101 cagctgcatg gaaaatggag acatgccgat cgtaaatata ttccaaataa tgggaccttt
    71161 caaccggaaa tatttcgtat ggaaacgtac aatactatcc ttgctgataa aatgactcat
    71221 cacgaaagcg gcaccggcgg ccatggagat caccgtagcg atagcggcac cctgtatccc
    71281 catatccagc cagaagataa agatcgggtc taggatcacg ttcaatacgg caccgatcat
    71341 catcgtgaac atcgcctttt tcggatatcc agaagcacgc atcacggcat taaagctaaa
    71401 gcttaatgta gccagcaaat tacccgggat agcgatatat aaatagtctt tcgcataagg
    71461 tatcgtctgc tcacttcctc cgaaccacat taacaaatca tccaagaaaa tcatactggg
    71521 gataatcgtc aaggctccga taatgaatgt caaagtgaaa gcgtttccta atacgttatc
    71581 tgccagatca ttcgccttac ggcctagatg aatggagacc cttgtagcgg ctcccgcacc
    71641 gatcaacatt ccaaatgcct gcataaagag tagtatcggg aaagtcaaag tcaatccgga
    71701 gatagctagc gcacccactc cttgtccgat aaatatacga tctacgatat tataaagagc
    71761 attaaccatg gtcccgataa cggcgggaat cgcataatgt accaacaaac ggcctatatt
    71821 ctcattttcc agccgccatg taatctcatt tgacatatat aacttatgat ttatgaatta
    71881 tgattgagat catctccgac acacttccta cgattctcgt gccctcttcc gcagggaact
    71941 gaatacgcag gctatccgga gcattacaat aaacacttat ataatcctcg ctaaccgacg
    72001 agggcttaaa gccattccgg atcaaggcat tcccaaccca ataagaagtc ataaaatccc
    72061 ccgcaacccc aataagcttt gttggagctg ccgtattcaa tttcccggta ttcggatcaa
    72121 acacgattcc ttccttactg aagaacgtct caaacgctcc tcccataatc aggtcttccg
    72181 gcgttccgca agccatcgga cgttttttct cttgcagcca caggcaatcc cccagctgga
    72241 tcgccaaatc aagatcatgc gtcgatagca gaatcgcttt ttgttgctct accgctaaag
    72301 tatgtaacaa gaccatagtc tctatccgac ttgtcacatc taaaaaggcc gtcggctcat
    72361 ccaacaatat gatggggcat tgctgtgcca gcgctttggc gatcatggct ttctgacgct
    72421 cgccatcact aagttccgac acataattat aagccttatg agcgataccg gcggcagcaa
    72481 gcgattcctc gataatcctg cgatcttcct gccttaattg tccgaaaaag ccggtatagg
    72541 gatgtcttcc taaagagacc aactcgtaaa ccgttattcc accggcattt gtcttctctg
    72601 tcaagacaac tcccaccagc cgtgagaaat taccttgtga ataagaattc agcggcttcc
    72661 ccattagctc gatttctcct cccagaggag gttgaaaacc acataatgtc ctcaataagg
    72721 tagactttcc cgctccattt aatccgagaa gacaggtcac ttcacccgga tatagattca
    72781 gatccaacgc atcatgcacg cgctttttct gtccgccttt caatatatac ccaatactta
    72841 aatcacttgt ctttatcaca gggatccgtt ccatagccac taattaaaat attgaatatt
    72901 tttccggttc acgattacgt aaataataac aggcgcccca agcatagggg taacggcatt
    72961 caatggcagg atcgtattac tgcccggtac caccatcagc atattacata gaagagcaac
    73021 gcaggaacct gtcagcattg taactggcac caacatctta tgattggaag agcctaacat
    73081 caaccgggcg atatgtggaa ctgctaatcc gacaaaggaa atggggccgc aaaaagcagt
    73141 agttgtagcc gttaatactc ccgtacacaa aagaatcgca atccgtgttc gtttgatccg
    73201 gatacctaaa ttagcggcat acatttctcc caataataag gcattcaaag gcttgatcag
    73261 caagatcgct aataacagcc cgattaacgc acaagttcca aagaatggta attgttccaa
    73321 ggatacaccg gaaaaattac caagccccca catcacgaac gcatgtaccc ggtctgtaga
    73381 tgaataataa ttcaagatag aaataaccga agaagctaga tagccaatca tgattccgat
    73441 aatcagaagc atgacattat tcttcacttt tgccgaaaaa tagataatca gtcccagtat
    73501 cacgcaagcc cccacaaagg ccgcgaggat taccgccata tatccgctga tcggccaatc
    73561 cgtgaactgc cccaacgtac caccgaaata gagcatgata gcggctactc caagattagc
    73621 gccatcacta atgcccaata tggaaggtcc cgccaacgga ttccggaaca atgtctgtaa
    73681 tagcaacccg ctggtagcca aggaagcccc cgccaataat gcggttatag cctgaggcaa
    73741 acgagattgc aacacgatat tctgccatgc gatcttatca gatcccttcc ccagcaaaat
    73801 atccatcacg tgatccaaag gaatcggtac ggccccatac gccagccccc caacaaaaag
    73861 ccccaaaaga accaccccta ataacggata aaaaagtagc gcttgtttgt tcatggcgca
    73921 aaggtataca aaaaagcgga gttatacagt gaatggtaaa tcaataaaaa ggccatccct
    73981 tacagtaaga gatggcctaa attattctta gttatccgat tcttttattt tgagaatgcc
    74041 gcataacccg gattctgttt taagttcgga ttcacctgcc aagcatcctg cgatacaggt
    74101 aacaacttca agtagtcatc agctttacgc tcacaattag attgcggcca cattcctgta
    74161 gtgaaacatc cgaaacggat atcatcctga cgggaataaa cctcccacgc taattccaaa
    74221 cgacgttcca attgtacttc cttcaaagtt acagtcgcat aattatggtc gctattgcca
    74281 tatcctctct cacgaatcgt attcaccaaa gcggtagctt cactaacact tccccctccg
    74341 cgtaacaaag cttcagcttt cattaaatag atatccgcca aacggaaaat atggaaatca
    74401 tttcccatag aacttgtcaa atccgaagcg aactcccact tgaagcaacg agctccatca
    74461 tgctgttcca cggcactcca attggttcca tcatattcca tgcccggaat catgttcaca
    74521 tcgatcgtat ggttcaattc gttgttatga tcggtcataa tcggcttgcc tgttgatttg
    74581 tctatcatca agccagtcaa gaacgtaccg tccaagcgag cgtcttcctc atcgaacaaa
    74641 cgtacatact ccggttgagc gcaaatacca ttccaagtac cactagcggt aatacccaaa
    74701 aacagataat ctttataatg caacgtatta ttgtgcaact cattcttcac gtttccatca
    74761 ttacccgtat cactgctaga gaacgtagcg gccaagatag cctcctttga attctcattt
    74821 gtcacggaga agttgtcttt ccaattaggc tctaagatat atcccatagc catcacctta
    74881 tcacagttat cgataacttt ctgataagcg ttaccggaga acgtaacccc ccaagcctca
    74941 gcgttcagat acagttttgc caacaatgaa taagcggcac cctgcgtaaa tgaaccataa
    75001 ttctcagttg tagccggagg acagatatcc ttgatttcct ctacttcctg aatcaaccaa
    75061 tcaaatactt cctgacggga agaattcccc gggaatactt tatccgtagg gtggaactcc
    75121 gtcagcaaag gaatatttcc ccaataatcc atcatcacat agatccagaa agcacggaca
    75181 ccacgcaagt ctgccacgtc ttgagccttc tcctcttcgg taaggatctc tgagttctgc
    75241 aatttacgga tagcctcgtt acaagtacca atcgcttctg tggccgcttt ccatgcgctt
    75301 ttaactcttg aggtctgaga ggtccatgta tgcatataga tttcccggta ttgaccacca
    75361 tcataccagt caccacctcg acgagtcgga gtcacagcca tagaaccgga gcattcggac
    75421 aaatgcatat actctgtcca aaacttcttc atcgtattat gtgagttacc gatcaaagca
    75481 ttcaactcgg ccgttgactg gccaaaatca tcagcgggca acttgtcata tactgtttca
    75541 tccaagtcca tacaggaaga aagtcctcct aataaaaaca atccagttat aaatgataat
    75601 atagttttcc gtttcataat aagcttatct ttttaattag aatgttaagt taacaccaaa
    75661 tgtaaatgaa cgtgccttcg gcatgtagtt acgaggttca atacccggag acaaacctgc
    75721 gttgtcatcg ctagcctcac cacggaaatt ctcaacttct ggatccaatc ctttataacc
    75781 tgtaatcacg aatagattct gaccggctac atataagcga gccttatcca accaatcgat
    75841 tttcttcgta ttgaatgtat aaccaatcga taagttatcc aatcgcaaga atgaagcgtt
    75901 ttctacataa taagaacata cacgagagtt ttcacttaat gtcaacagat tatcgttatc
    75961 cattacattc gttccatcga tatatgtatt attaccgtaa gctgccaatg ggttgttcaa
    76021 taccttattg ccaattgttc cacggaagaa gaaacttgcg tcccagtttt tccagttgaa
    76081 tgtgttattc caaccatatg tcaaatcagg ttgagcgtca ccaacatacg tacggtcatc
    76141 atccgtgatc tgtccgtcac catttatatc ctcaatgata aatttaccat tctcatcaag
    76201 gccattacat ttcagcatga agaactgtcc gaccgggcga ccttcctcaa ctacgtgtga
    76261 agtcacacct gaagcaccgc gaatccaagg atcacccacg taaacacgtc ccgtagagaa
    76321 caattcatta gacagttttg tgatctcatt cttgttatga gcaagattga gagaggttgt
    76381 ccacgtaaag tccttattac ggatcacgtc taagttcaat aagatctcaa cacctgtatt
    76441 cttcatatca cctacattcg cttgaatctg attgtatacg taagtaggag tagaaacctc
    76501 atagttgtaa agcatatctt tcgtacgctt gtcgtaccat tcgatcgtac cgctcaaacg
    76561 actattgaac aaggtgaagt ccaaaccgat atttaacata gcagtctgct cccatttcaa
    76621 gttcgggttc gcgttctgtg aaggacggaa agctgtcggc caagatccgt tgttataata
    76681 agtaccagaa gctgaataca aatccaatga cttataaggt ctcaaaccat cttggttacc
    76741 ggtaattccg taacctgcac gtaatttcaa atcattgatc cacttcgtat ctttcatgaa
    76801 agactcttgg ctgatacccc aagcagcgga aactgaaggg aaagtacccc acttatggtt
    76861 agcaccgaat ttggaagaac catctcggcg aaccgtagcc gtaatcatat accgctcttt
    76921 aaagctataa tgcgcacgag cgaacaaaga gatcagttta tattcattcc ggctggaagt
    76981 aacattaccg atcttcagca agtttccgga ttggatatta tcagcgccca tcgatcctac
    77041 ggcgaaattc gtagcctccg atttctggtc ggcgtacaag ttattttccc aagaataacc
    77101 aacgatagca tcgaccttat gctcctctgc cgagccaaaa gctttcgtat aattagcggt
    77161 ccactctaac aagttacgat cccatagtct attacgacgg attgccttac ccgtatcacc
    77221 ctgtccacga gagttccgag gatcttgcca ttcgctatag tcagatgaga aacggctctt
    77281 atacaggttc accttggttg tcagtccatc caaaatagag aactgtacat caccttgtcc
    77341 atagaagtag ttattagctg ctttcttata gttctgatct tggttctgaa ccgggttacc
    77401 ttgatcataa ttgtggttgg catccgtgaa ataagagccg tccgcattat aaaccggata
    77461 aaccggaagc atattgtaag ccaagatata gtcatcagaa aacggcatct gcatatccgt
    77521 cagcgttgcg gcacccgtta atccaatacg taaacggtcg ttgatagcac gttgctggaa
    77581 ctggaaacgg aagctatgac gagtcatgta gttatcgcga gccacaccgt tacgatccaa
    77641 gaaagtataa gaagcacgat aattactctt agaagaacca cccgacaaag aaagagcgtg
    77701 ttgttgagaa acacctacac gagtcatctc atcgaaccaa tccgtgtccg agttgtactt
    77761 atcataagta gagatatctt tacccaacgc cttattagcg gcacgccact cagaagcgtt
    77821 caacatgtcg ggcttgttcg caatggtaga ggcggtaaga taaccatcat aattgatctg
    77881 ggttctggaa ccggaacctc tcttcgttgt gatcaagatt acaccaccag cggcacgaga
    77941 accgtaaata gcggcagaag aagcatcttt caatacagag attgactcaa tatccgaagg
    78001 tgatacagta gacatatcac cacccggaac accatcgatc acgatcatcg ggccttggtc
    78061 gttctgcaag gtagaagtac cacgtaattg aatctgggaa ctacgagtta catcaccgga
    78121 accagacgta atagtcagac ccgctacctt accttgcagc aagtcggacg cgtcacgatt
    78181 cactccttta ttaaaatttt cctcggaaat gttcgctacg gaaccggtaa tctccctacg
    78241 agtctgcgta ccataaccga tagctacaac ctctcccaga ttcacgacag aggcaccaag
    78301 cttaacatct acggcagagc gccctttcac agcttcctct accgagttgt aaccgataaa
    78361 agacacttgg agaattgctt ttttcaggtc attcacacta agggtgtagt taccgtcaat
    78421 atcagtgatg gtaccgttgg tagtaccttt ttccacgata ttcgccccga taataggctc
    78481 acctagttcg tccagaactt ttcctttaac agcgcctgac tgggcaaaag cggctgtcat
    78541 gcaaaaagac attaacacgg aaagtatggc tacattccag tgtttgaaag aatcaaagat
    78601 tttctttcgt tgcataatta cttaattttt aggttaacga tcatttaatt cacaaataca
    78661 attgagaatt tccatggcaa atgtaactta attttttaaa ataaactatg attatgtaaa
    78721 aaagtaagga aaatcaaaca ggaggtcttt cggtagatca aaataaatgt caacggataa
    78781 acctaaagag tgacgttttc atttcgataa gccacttata gtgacacatc cttttccccg
    78841 acaggctcat ctacaaacat aaataaggag aaaatcgttt ctttagtggt tttaaggtag
    78901 aaaaagagta cttttccctc gattacaacc ctgttgtaag atacttacag tagtattata
    78961 aggtacttac ggtagtgttg tagcatactt ccgactgtga ttcgcatcac ttccgaatga
    79021 aaaaccaatc acttccgaat aaaaaagcct ccttttactt gttaagcaag aaatagaggc
    79081 tctctttttc gctggaagaa aagggaggga aacgatatac atctacaaga caaggtgttg
    79141 ccattatttt cattcaattt cggaagcctt acgcccataa gcccggaaaa atcgattctt
    79201 cgggacttta aaatacaaaa tgtcaatttg tcaatctccc tttatccttg tctatagttc
    79261 tggacggact acgctaaaat ctatctctcc atcctctcct tctcctttat caacccattc
    79321 cgataggcgt aaagaagttt ctccaagtcc ttgatctggc tttgaagatc cgcaccctta
    79381 tccgtatctt tcaccatctg gcgatgggag cttaattcta ccacgatcgt ggtggatttg
    79441 atatccaagc cttcctcgat cgctttcgcc cgggattcga agggttcgtg ttgcacaagc
    79501 tggaaaccac gggagtgata tactaatgta tagcccgcga taccggtttc caaatgatac
    79561 ggacgggaga aaccgccatc gattaccaac atcttgccat tcgccttaat gggattctca
    79621 ccttgattgg aacggacagg gacatgtccg ttgatgatat gccgatgcat accggtcacc
    79681 ccaaactcat ccaatatctt atcacaaatt tcctcttgct ctcgtaacgt ataataagcg
    79741 cctttttcct ccttatgagt ctcggcctct tcgataaagg cacgctcgaa agtagccatc
    79801 ttgcttttat cgaataacgg ggagtccttg ccgccccaaa gataccagat ataatcatgc
    79861 gcatattcca cttcttcctg ttccccggtc ttgaaataag ccgtacggat cagttggtct
    79921 acacggtcca acaaagcacg gcccttataa tcctgcccca agatacgtac tgacttaaat
    79981 gtaccatccg gattcatcgg gatagaggca tgaaacagta aattggaatt acaaacctga
    80041 tacattcccc catgccggaa gaaacaacgc atatgctttt tcatcttctc gctgctctca
    80101 aaagaatgca atatctttcg gatcaaatcc tcttcctcaa tagaaagacg atacggatct
    80161 ttcgggtcta aagtaggcca gttagtatct ttaagcgtat aatcctttcc atcgatatga
    80221 accactcccc gcttcagatc gatatggtgc aacaacatcc ggtcatccat ctcaaactcc
    80281 ggacgacggc ggatgatctc accctccagc ttgaactgga tgatggtgat cgccttgtgc
    80341 atctgggcga tcaaacgggt ggtcttctca tccattgcat tatcggcgaa ctttgttttc
    80401 ggcatgaata acgcgcaagg atcatcccca tacgcctcca tcgcgaaagt ggccaacggc
    80461 aaaagattga taccatatcc atcttctaag gtagccatat taccaaagcg taaacacata
    80521 cgaatcacgt tggctatact taccaaatta ccggaagcgg ctcccatcca taagatatca
    80581 tgattacccc attgaacatc gaaattatgg taatcgcaaa ggatatccat gatcagatga
    80641 gcgcccggac cccgatcgta aatatcgccg atgatatgta acaggtcgat tgtcaaccgt
    80701 tggatcaagt tacacatagc gataatgaaa tcgtccgcac gtcccgtgga gatgatcgta
    80761 caaataatct gatccacata agcggattta ttcggctcta cggaagactc gtgcaataac
    80821 tcctgaataa tataggagaa ctccttgggt aaagccttac gtactttcga acgggtgtat
    80881 ttggaggaca cgttccggca aacacgtacc aattgattca aggtaacttg ataccaatct
    80941 tccagatctt gctcttggct cttgatcagt tccagcttat cctccggata ataaatcaag
    81001 gaacaaagct ccttcttctc ggattcccgg agcgtattac tgaaaatctc gttcaccttg
    81061 cgctttacgg caccggaagc gtttctcagc acatggctaa aggcttgatc ctcgccatgc
    81121 aaatcactca agaagtgctc cgtacccttc ggtaggttca agatcgcctc cagattaatg
    81181 atctccgtac tggcatccgc gatcgtcggg aaactccgtg ccaacaattg caaataccgt
    81241 aaatcgtttt gtacagattc ggctataata tcttttgtca tcttatctct tatttatacg
    81301 cgaatataaa tagatccggt catttaaacc gaacctgctc cggtttattt ttctcggcta
    81361 cttgctggat ctcatagggg ctgacctcta cggcaccttt cgtcaattcc ggaatattgt
    81421 aggaatacaa ctgatagtca tacttatccg gatcttcttg aggcaataag aacggtttcg
    81481 aaggcttacc gtctttccct atatgacaaa tataaggtaa agtatataaa ccgttatccc
    81541 ggcggctact aaatacgacc caatcactat tactactcca agaatgatag ctatctgtat
    81601 ccgggctatt caacgcagac atatccatcg ctgtccgatt ctccaaatcc atcatccgga
    81661 tctccgcatc cgggtgccaa atagggaact gcccataagc ggtttccgtg tacatcagga
    81721 aacgtccatc gggagagata cggggaaatg tatagctcaa gctatccgca tgtaccaacg
    81781 tatcgatcgg gaagctgatc tcgccacgat ccggatcaaa cgcaacacga cagagattat
    81841 aacgtacctt atcataattc tccggcatct tctgggccgg ggccgtacag aaataaagcc
    81901 atttaccatc cggagagaac gcagggaaag tctcgaatgc atcttttgtg atcaatgagg
    81961 ctttcgaaag gatttctttg tttttcacgt catacaccac cacatcggac tccaagtcga
    82021 acacttccat ctttttctct ttcacggaat ggaaaaactg tttgatatca tttaccgatg
    82081 tggtgatata gcgcccggaa ggatgccaga aaggatacgt catattactg atcgtcccat
    82141 tcgttttcgt attcaattta ctgattttct tgtcttggac aatataagtt cccccattcg
    82201 ccgcacgcat atggaacatc atctgccccg ggtctcccat acaaaaagaa tggcagttca
    82261 tacaattata gccagtcata tcgttacgga taatcggctg ttcgtcaaac gactccaaat
    82321 tccgctgata aatacccaca atatgccatt tctcgtatcc cggctctatc aaacggtata
    82381 ctaaatgaga gtcgatcgct tgatcactga tatagacaga gaatggtgcc catttagtcc
    82441 attcgtctcc ctctttcgtc gtgatcgtta caaaaaaggc tttaccttta ttcgcacggg
    82501 taagccgttc ccaatccttg gacttaaaac agatcgtatt cgttccgtaa tactcaaaca
    82561 ccccctgctc gctaccctcg atcttcgcat agcatttttc agcgggcacg tcaatacgga
    82621 aattcaatgg ggctatatta taaggtatag taaccccttg gtaatccggg aacatcggcg
    82681 ggggagacat gcgttcgttc tcggcaacaa caaagccacc cggatgtacc gcccaaaaac
    82741 ccaagtatag tacaataacc agaacttgca atagtaaata tccgatcaca aagtttcgga
    82801 cgatctttcg tttcctcgta ttatccatca taattattgt cgtttaggag tcggggtaaa
    82861 ttgagcgtaa taataatagg tatcgccaaa ctgcgctttc aaggcggcag gaggcatgcc
    82921 tcgagccact ttcataaatt gcagaaagcg gttttgtacc tccgaactga tcggatagct
    82981 tttgaacgcc tccgggtctt tctgcacggc agcgaaaaat aggcatatag cctcttgata
    83041 gagaacggga aatgactcgc ctcgctcttt catcaattcc atataatgca taaatgtcat
    83101 caagtcttta taaaccaaca agtatcccat tccatactca aaagccggac gattatcggc
    83161 atgatcgtcg atcaagaaag ccagcgcatt gggaaatgtc aaggtcaagt ctaagggatt
    83221 atccgttacc ggaagtaccg cccgcttcgc ctttatccaa tcggtagagg cacaaaccac
    83281 ggagtcgagc aacgggcgct gcgcttttgc ccaatccctg tagtggggag tcgattcaag
    83341 gatcttaata tatttctcgg cggcacggta ttcgccggtt accagataag tctccaccaa
    83401 acgcttcatc aaacgaggct gcacgcaacg ttgcgagctt aatacaccca caaaggcgaa
    83461 acgttgcgct gcgtttacct gccctacttg ccaagcaacc tcgctcgcct cgatcaatcc
    83521 catccggctt ttcggatcgt gcgggataaa gccctccacc ccgatctgag ggaaacgcat
    83581 caaatcgcca gaaaatcgtc ccgtatgtga taaagccaga ttcaaataaa tcagggcatc
    83641 catatcccgg accgaatgcg cacgagcatg tgagactatc tcttgccatt ctccctgccg
    83701 tgcatagtaa tcgtaccgat aggcctgctc catcgggtct ttcttataga gaatcccata
    83761 agtcatcgct atcagaagga aagcgtaaga aacgattcgc ttccaagatt ccttacggat
    83821 aaaaacccgg ttccttacat aataaagaat taaaacgatc aaaggatatg aaagcccgat
    83881 atatcctaaa gaattaggta tcggatattc gggatggcat agatgtttgc tgaagaacgc
    83941 ttcccgcatc ggaagaatat aaaccgtacg catggcgatc aacggtagca aacctcccca
    84001 agcgatagcg ataatggcta ctccaaaacg agccttatcc tctttagcac aacactcata
    84061 aaccgcgatc aataaggcca ataataaatt agcgggtgcc gcaaaaaaat aagagccccc
    84121 caaaaacaag aagccaaaga gataacgaag ccaatcaatc ttgattgaag tatacaaata
    84181 cgcaagaacc tgcacgaaag cgagcatcgt caacaaggcg attgactcct gcggatagat
    84241 ccaaattaaa aaagagggaa gaatagccgc caacatagag gcacgcaccc cacaagcttt
    84301 taagtaaagg aaaaaacagc cggagatcag tcctaataat aaagcgatca ctaccgaagc
    84361 tccataagga tggataaacg cgagcgataa gaactcagtc acatattcat tcaatccacc
    84421 cggttcggcc aatcggtctt ggaaataact accggtagtc tgaaacatca tatactgctc
    84481 cagaaaacga taccaatacc gaaaattcaa ctctatgaat aggatacttc ctataataaa
    84541 aaggaatagt ataatagtat tattgttaac aaatagtcta ttcttcattc tccaactgtt
    84601 tttcagatcg taaagataga aagtatatag aagatggcaa aagaaaaggt ttaattatta
    84661 tattgaacac ggaacacacg gagcgtgtgc tccatgttca aagctatatt tcttacatct
    84721 gttgctcgcc gccgccggaa ccgccgctct tcatatcatc gttgctgata cctcttttta
    84781 ctttcttgat ggcatctttc aaggtgccaa aacgataaga tacactaacc attaacattc
    84841 tcatcgtacg gtaattgatc tcacgacgga agaaggtatc atcggaagta gtattttcca
    84901 tcttcattcg cttccagaag gggttttgga aagacaactg gacagatagc tttttcttca
    84961 agaaatcctt gttcacggag attcccgtga aatagaatgg agagcctttc ccctgtaact
    85021 ggatccaagg agagaaatat cctccctgta tgttcacacg gaaatccaac gggaaattaa
    85081 actgcgtacc ggcgaaaata cgtccgctga atccactatt cgccatatca ttcttttcgc
    85141 tcttcaaatc cgtataatcc attccaccat tcatatagat acggaacaaa ggaaccggat
    85201 tccaatttgc gtatacgaat aagccggtag attgtttctt tccgatatta ccgtaggtgg
    85261 tttggaaaac acccggattc tccggatcga taaaggtata ttgctcgatc gaattattga
    85321 cgaacgtata agtagcgctc gcgttaatgc tgaatttctg ggcgaacata ctatagttca
    85381 agtttatatt attacttttc tccgagtcca gattcgggtt accgaaggat atgttctgtg
    85441 ggtccgcatt gtttacataa ggattcaaat accagatacc cggacgctgg atacgcatat
    85501 tatatcccaa gcgaagctgt tgcgccatac tcaattgata agagaccgta gcgtttggca
    85561 ccacgtcgaa ataatgggta tcaaagttca tatcgggagc catctcatat ttcacgtcca
    85621 aagcggttcc ttccgcacgt acccccgcct tcacgccaaa cttatcaaac ttcatcgaat
    85681 agcccagata agcggaatag atatgttggg tatgacggaa atggctatct ttagaagtta
    85741 tgtcctccca tatattcaac gaatcgttga aagcggtacg atccgtatta ctccggctct
    85801 ggcggaatat atattttgcg ccaacctcca aggtctgatc cttccacgta ggggtcgtat
    85861 aatccacctg cccggtgtgc tcgttcgtag aagccttgtt gatattattt tgcggatagc
    85921 cgagccaagg attgtaattc acgacattct ttaattccgt ataatccttg ttatcattgg
    85981 gagaatggct gaaacggtag gagatcgtca gcaactcatc ttttttatgg gtagagtgtt
    86041 ggtaatccac gctcacgtcc gtagaaccaa acgtttccgt agcgtccgaa ttacgattat
    86101 aatcgtatac cggattacga ttgatatcct gcatattcac cgtgtattcc gaacggttcg
    86161 tcatcttacc atggaataag ttcgccccta cggtcagcaa gttcaaggag tcgatctcat
    86221 aactaccttc cagcgaacca aactggaagg gtccgttatt cttcctacgt ccattttgcg
    86281 tcaagaaatg ttgctcgtca ttttccaaat cctcacgtat cgaggtagac tcattccaag
    86341 gctccctatt ataattgtaa ttataattcg ctgtcaaccc gaacttacct gctttaaggg
    86401 atatatagcc gccaccgcct acacgcccca acgaactacc gttcacacga accgtaccag
    86461 tatatccttg tagagcgttt ttcgtcgtaa tgatattaat aataccaccg ataccctcag
    86521 cgtcatattt agcgcccggg tctgtgatca cctctatgtt tttcacggaa ttggccggca
    86581 tactcttcaa tacctcagct ggattgttac tcaacaggtt agaaggcttg ccattcatgt
    86641 agatcttaaa gttcgtggag cctttcaatt ggatttggtc atctccgtcc acggttacca
    86701 tcggtacctt gcgcagcatt tccaatgtat tgtttgtctg tgcctccgga tcatcttcca
    86761 agctataggt aagtttatcg atctcagcct tcaccaaagg tttctgtgcc gtaaccgtca
    86821 cttcccccag ccgctggtta tcctcctgca tatacaactt acccaaatcc aagttcctct
    86881 gtttatccga gatcgtaaat gttttctcgg caggagcttt tcctatcgat tgcatagaga
    86941 tgatgtattt accggcgcta ctcaatggtg cctgaaactt accatccaca tcacacgcta
    87001 aaagcttgac cggcttatcg ggggtcttcg ctaaagcaat tctcaacgtc gcatagggta
    87061 cggactcgtt actcagcgag tctaacacct gtcccttaat tgaataggaa cctgtcttgt
    87121 ccgcttgcgc atacagagga agcgcaaaga acagtaccca aaataaggca aacaatttct
    87181 ctttcatacg ttcatctatc actataaaaa taatacattt tactgcaaat tacactattt
    87241 acgatttcat cgtacaaata aagtcattaa taatgttcat atttcctttt tcttctaaag
    87301 aagtctgaaa aaagagtatt ttttcataat agacggacat caagtaaaac aggttgcaca
    87361 ataatcctag gaatctttga gaaaacgaat atattgttat ttttgcattc gtaattcttt
    87421 aaaatacaat gtcatgagaa ctatcttttg tgtattagcc actttgatgt tgggtttgac
    87481 gagtctgcaa gcccagagtt taaaagccat taagttgaat gctcccgaca agacccgggg
    87541 cgcttcggta atgaaagcct tggcagaccg tcactccgag cgcgagtttg ccaacaagaa
    87601 actcagccta caagatcttt ccgatttgat gtgggccgct atcggtatca accgggagga
    87661 tgggaaacgt accgccgctt ctgccttgaa taagcaagat gtggatgtct acgtattgat
    87721 ggaagagggc gcttatctgt atgatccgaa agcccatcaa ctgaacccgg tagcggaagg
    87781 cgatcaccgt ccactgattg gaggaaagca aacctccgtg aactcagctc ccgcttgtct
    87841 attgatggtt tctgatgttt ccaaattcgg caatgtaggt acaccacaat tacgtgagcg
    87901 ctttggagcc ttagatgccg ggctggtctc tcagaatatc gccttgttct gctccggatg
    87961 tggcttggta acggttcccc gcggcagcat ggaggctgat gctttgaaaa aagtgttgaa
    88021 gctatccgac tcccaaatcc cgatgatcaa tcatccggta ggatacgcaa aataacgtca
    88081 gcactcacgt aagcccccga gaatcatctt gtgggcttac aagaccgctc acgcaggagg
    88141 ctgagaacaa tctttacaaa aaatagatat tccgactctc cgaatatgat caaccaattc
    88201 catattcgtc aatttatgaa aaatagagag atcaaactga taaggtaata ataaatcatc
    88261 aatcacaaac gcaatctgat ttaaccgact acgtgtcaag tttgccccca ccaaagatat
    88321 atccacgtcc gaaaaaggtt tatggtttcc cttagcttgc gaaccgtaaa gtattacttc
    88381 ctcaatatcc tcgtatcgag cgtaaaactc acgcaactta ttcaattcta tgtcactcaa
    88441 tccatatttc atttacagct tcatctagtc tcattttccg atatacataa catcctctct
    88501 tcaaaccggc aaaatagtgg ataataaacc agtacgatat tctcataaat ttcagaagcc
    88561 acatcgtcat cataattatg agaagtcaaa ttacgatcct caattgtctc catccatcgt
    88621 ttatcttcta taagccctat ttgtaaagcc ttacgtatag catcacgtga acctcgaata
    88681 tccgtataac cttgatattc cgcataatct ttcatcacct tccagactaa ttcacgggta
    88741 tattcaaaac gctggattaa tccttcttgc aaaagttcat caatctcgtc cgctaattcc
    88801 aaccgccaag atacaatgtc caccgcttga cccaatttag ccaaagcctt acaataatta
    88861 gaaaatcgct gtaaccaacg tatatcttgt gccatatatg taaactttag aatacgaaga
    88921 taagaaaaac agaagatatt cctacattca tttcttgaaa aatgcaaacc aagcaatcaa
    88981 agccagcagc acgaatataa ccaccaagat cgtattcccc caacgaatca ggaaggaagg
    89041 catctcgcca atcatgttgc ggactttctc gctacgcaac tcgatacggt tttgatccga
    89101 ttctgctttt ttcttcatct cattgtatgt cgacatatct ttaattcccc aactctaatt
    89161 gattcttcac taaattataa taagcgcctt tgcgatcgat cagcacgtcg tgggtgccta
    89221 cctctacgat acggccttta tcaagaacga ctatttgatc ggcattgcgt acggtactta
    89281 atcgatgggc gacgattatt accgtcttac cccggtaaaa gtccgtcaga ttctccacta
    89341 tggcacgttc attgttggca tccaacgaat tcgtcgcctc atcgaaaaag agataagaag
    89401 ggttcttata aaccgcccgg gcaattaaga tccgttgacg ctggccttgg cttacgcctt
    89461 gaccatccgg acctatcacc gtattatatt ttaagggtaa gcgctcgata aattcctcta
    89521 tattggcgat acgagctgcc aataataagc gagatttatc aatctcaccg tcatccacgg
    89581 caatattgcg tgcgatcgat tcagagaaca gacaaccgtc ttgcatcacc gcaccgcatt
    89641 ggtcacgcca ccataaaagg ctgaaagatc gcaaatcatc tccacccact cggatatcgc
    89701 cttctaccgg attatagtag cccaataata acttgatcaa ggttgttttc ccgctaccac
    89761 tcgttcctac gatcgccgta atcttgcctc gaggtatttt aaggtttatc cgctccaaga
    89821 ctttcggcga atggatgccc tcatattgaa acgtcacgtt acgaatctca atgtccctat
    89881 cgcttccgtt aaaaccgatt atcatacgtt ccggcgtctc ctcttcttcc cgatcatgga
    89941 tctcgctcat ccgttccaga ctaatcttca cgtcttgcca actataaaga aactgcacga
    90001 actgttccac cggagcgttc aactgcccga taatatactg tatagccaac atcataccca
    90061 acgacaggct acccccgatc acagccgtag cggcaatcac cgtaatcacg atattcttta
    90121 cctcattaat caagatactg ccggcctcct gactctgttg cagccgcatc gattcgatgt
    90181 tcgtccggaa caagtccgct tgtatatcct cccattccca acggcggcgg cgctcacaat
    90241 gctggagctt gatctcctgc atgctgttca gcatctgcat cgtcttcgac tggtttcgag
    90301 cccgctgctc aaaataggta taatccagca actggcgttt cttcaagaaa agcgtcaccc
    90361 atatcgcata taaggcacta cctagcacga atatgccaaa tatcaatcgg ttataataaa
    90421 gcaatacccc cccaaacacg atgaaactga aagcggagaa gagcaccgtc aatgtctgcg
    90481 ccgtgagaaa acgctccacc cgttcatggt cgtggatacg ctgcaacaag tctcccgtca
    90541 ttttcgtatc gaaaaacgac atgggcaaac gcatcaactt aatcaagaaa tcggagagca
    90601 aggagatatt cacccgagcg ctaatatgca ataagatcca acggcggata aaatccacgg
    90661 aggcacggct cagcaccagc atcaattgtc ccaccaagat cagatagatc aaattcaaat
    90721 tctttccggc tatcccttta tccacgatcg cttgcgtaag aaacgggaag atcaattgca
    90781 agacactacc tagcgccagt ccgagcaata attggataaa gaaacattta tagggtctca
    90841 tatatcccca caagaaacgg aagggatctt tccccgtatg ccgttcatct ttccgctcgt
    90901 aaaacgcggg ggtcggctgc aaggccatca atatcccttt ttcctcccct ctcgtacggg
    90961 tactgatcca cgcattacga aactcatcct cattgatccg taatagattc ttgccgggat
    91021 cggcaatata gaaaacatat tcaccatccc gtttcttttt agcgtcatag agtacgacga
    91081 agtgatcctg gttccaatgg aggatacagg ggaaagggcg ctgctccacc atcttcccca
    91141 gggtcattcg tccacatatc gtacggaatc ctatatactc ggcggcatca gagataccca
    91201 acatagagac tccttcccgg gtgacgacac aaaggttctg catcgtcgcg gcggaatact
    91261 ccttgccgtg gaacttggcg atcatgcgaa ggcaggtagc gccgcattcc atggagtctg
    91321 gttgtttgat atgggggaag ctcataattt aataccttcc tctatactat acacattttt
    91381 ccgttctttc attgctttcg acttgttttt acggaatgta taacgaagca agatccaagg
    91441 ccgaaaagag gcactgattt ttcgttgatc gctgtagttc tcatagctac cactacgtaa
    91501 ttccatcgag gtacgataag taaccaaaca attctccatc gccacggaaa tatagaaata
    91561 gtccgtaaaa ttataagaga cctgtaccat cgaaaaagaa gggctatgat acttcacacg
    91621 agagattggc gtataggtat aattgttata taatatatca gcacccaaat accacttctt
    91681 ataattcgca ttgaaataca aagagcaact aaaccctttc ctcgggtctt gattctcata
    91741 ataatccacg acatgatacg cattgacacc tatacgccct aaattgccta tccgataaga
    91801 cagacttccc cctatgcgta aattcttata cttcccgcta ttcctatagc tactgatata
    91861 aatatcctct tcgctgaatc catacgattc caccaagtcc gtactgatcc gataagagac
    91921 gctcggtgtc aaataaaatc ctttcgtgtt aaatgtcaag gataggttca atttatgatt
    91981 ttggctcgga agcagataag gatttccttg tgtcttcact aaagaatccg tagacatatt
    92041 ataaggattc aattcgctct cggtaggagc cgtattggta agcgtgtatc ccaatctcgt
    92101 agatagatga tcgctaaaat cataattacc gcttaaagaa atgcgaggct tgaagtaatg
    92161 attagaggcc tcacccgctt tcagccaaat tccttccagc ccagcagaaa gcatataaga
    92221 aaaacgcttt atagactggc tatagtccgc atacaaatac tcttcccatt tctcgtgccg
    92281 gaaagtaggc attcctatac tcacttgacg tatacgatca ctcgtaaaac gagtctgatt
    92341 ccctacattc aagctacctc catttgcaaa atccacatta taatccacat caaaacgacc
    92401 ggaattccgg tcgttcttat ataaatatgt attcagataa gaccaatcca gatatgactc
    92461 cgagcgattt ccgtcattct cgttatgatt cttattgaaa gcaagggtcg tttccaatat
    92521 atggtttttc gcaaacgtat gcttatggaa caagctagcc gtaaaaatat acgattgatc
    92581 cttattaaaa gaagaataat cgaattcttg gggtattcca tccgttaaaa gtccatcacc
    92641 ccaacctttc ttcttattga tttttttatt accatacata tgagctacga tataatcctt
    92701 gtctgtacac atccaacgga attgcaactc acctaaatag ctagtaccat ccaaacgttc
    92761 ctctcccttc gtccatttac tataccccgt atttagctgc cgttgctcct gttccgagcg
    92821 atcatcatac aaatagtcca ctgaagctct tccataaagt gcgtatcgag agtttccaac
    92881 ctcaaaatac cctaccccaa gccccttacg gaaagggaca tcatgccgcg tggctccttc
    92941 caagaagata aaaggttgtg tcttcttttt caattttata ttcaatatct tttggtaacc
    93001 atcctttaag taacgggctt tcaccacatc gattatctcc acggattcta tctctctcgg
    93061 atcaagagtg gcgattcccg agttataacg attcccgttt atcaatatca agggttgcgc
    93121 cccatcctcc aactgcacct tccggttagc cacatccgag tacaagcgtg ggatctcttg
    93181 cagggcccgg aaagggtctt tcatattttt agccttctct gacagataaa agatctctcc
    93241 cgtagcggtc cgattcactt gatcattccg attacccgtc accattactt cgtccaatac
    93301 gaccgttttc tcaggtgtca gcaagaagtc ttttctaaca tccctgtttt ccactcgcaa
    93361 tatttgctcc tgcgcattat accccaagaa aaacaaacgt agctcatacg ctccctcctt
    93421 caatccatct atacgaaaat gacctttttc atcagttaaa gccatggccg ataacgagtc
    93481 ttccacactc aatatcacct gtaccccatc catcatcttc cgcttctcgt ttgtaattat
    93541 tcctgagaaa gtgtaagact gggcagacaa tgtgaagagg ccttgtgaga tgaacagaag
    93601 ccagaaagcg atagttctca tggtattatg cgtataattc ttcttttaat aattgacatt
    93661 tgaaaagata catcagatat tctttcaaag tcatattgat tgcgtcaaat gtacatatat
    93721 tttcccccgg atgcaacatt atttgtttat tacatggtcc caaacaggca ggcagtaatt
    93781 tacaatctat acaattttga ggcaacatct ccttcaacca ataagaaact tttgtctcat
    93841 tccaatgtac ctgtccggat tgtaaatcaa attctcctaa cgcattttga tcatcaaaag
    93901 aagaaatcgt agaacactta aaaactttac catcataatt aaacaaaact tctctatgcc
    93961 gttcagcaaa gcaaacatct ccttttggca taatataata atccaataaa aatttcttat
    94021 ctaaaaactt ttgaaccgaa gcatgtaata acggcacatt aactttatct ttttctagtt
    94081 gccacacttt tttcaaaatg acaaaacaat acttacgatc tagaaaatcc aaatcaccaa
    94141 tgatttcatc tattttctct aatgtcttat tatcaaagtt tattcttacc gcaagccacc
    94201 tattgggaat tttatcatta ataagccgaa tagttctcaa tgtcttctca taagtatcct
    94261 gattcgggtt atccttatct ttctttattt gattatgatg tattctatca ccatccaaag
    94321 taatttggaa ttggcattca aagtttttta aataatctat aatagattct gttatcaaaa
    94381 tcgcatttgt tgtaaattca gcaattagat ccaattgatt aacttggcaa aagtttctcg
    94441 caaaatccag aatttctttt atccctctga aatacaaaaa aggctctccc ccaaagaatg
    94501 ataattttaa tatcctataa gatgttttaa tatattcttg ttctatattc ttttttatag
    94561 cttctattac ttcactcttc aagaaacttc ccgctattct attctcgtaa cagtaccaac
    94621 agtttaaatt gcaatccaat gttgtattca ccatgacttg atacatagag gcatcaaatt
    94681 gcatcctttt tttccgaaac aagacaatct ctctttcatc aaaatcatca ggaacaatat
    94741 attgattatc caccaaagat ttatataata caggatcaga ttgctctaat tctaaaatat
    94801 tttctttttt atatttttca tatctcacat tatttaataa tataaattta ttattaaatg
    94861 aattataaag taaataaacc tgtggcaaaa ctttctctac aacctgataa tatatcttct
    94921 tcatttcatt tttcattaat ttctcgatag aaatagctga tgccttctcc ctgttacaaa
    94981 gaaagcatca aactaaaaaa actatcaatt agccacacct ccctgaagaa ttattgactc
    95041 ctccacactt acctgagcca ttgttagtac cagaacaact tccatcccca ttattcggag
    95101 ccttatcatc tggatcctct cctccacgaa ctaaaataag ttcattttcc tctagcctct
    95161 ctaaaataag gctaggcaaa ttcattaaat cattcataat atctaaaatt tatagtttat
    95221 aataggtcat aatctatgac cgtttcattt actattttac ttatgactgt ctaggatttt
    95281 cttgtggaca cagaaccttc cgtccatcct caatccaata ccattcgtca gtctcttcat
    95341 cataatgcca ttcaccacct tttatagcgg aaagttcttc cttcgacaac aaatcaccaa
    95401 tttccatgtc tatatgcttt tttagtctgt tacaaaaata taagtaaaat ttcgtactct
    95461 atctaacaaa cacctaattt tcatctaaca aaaagctaac aaaacgagaa aaacgcatct
    95521 tttttaagat tattcactat cttcacatcc aaaataacga atctatcatg aaacactcct
    95581 tatatattgc ggccattatg ttgctagtct taatactctc ccaaggatat tggctataca
    95641 atatatataa cgctgaaaaa tataaaacgc aagaagtcct tgaagagcta ttcgaagagg
    95701 ctatcaagca agaaatgtcc aagcgaatgg ttagcaacaa accgaaagac cccaacaacc
    95761 ccaaaagaat cataagaaga gctagtgata tgacaccaga ggaacgagcc aagctaaaag
    95821 gggataccat aatctggcca caaataaaaa atcggaatct aaaagataac tatgccgacc
    95881 tattagcgca acgtatgcaa gacggtctac gtaatgcaaa tagaccctta aaaccaaatg
    95941 tattagacag cctattcaat aaaacattaa ctgatcacaa tttacaagca atatcttata
    96001 tagaaatatc agactctacc cggcaaaccg taaatacggt aggaaaaaaa ttcaaccttt
    96061 cattttataa gttccaaaca gaaaagctcc cgataggaac gcagggatta caatatgtac
    96121 aggctttcgt taaattacct ctttctgaca ttgtccaacg aaagctcttg gcttttatcg
    96181 tatcttgtct aatcatcctt acctcggcga gttgcctata ttatttatta agaacaatac
    96241 gtaaagccca cgcccaactc cgagaccgtg aaatagccgt acatagcgct atccacgact
    96301 tgaaatcccc gctgaacacg gcgtatgcct ctatggatct tatcgctagc ctagagaatg
    96361 aaccgatgaa agtgaacata ttaaataccg gaaaaactca gataaaacag ttgatagaga
    96421 tcatcgagtc catgctgtca ctattgaaaa cagcggatgg aaaagagagc acacgaaagt
    96481 cgcctataga tattaaatca tttattgagc aaacctacca agcgatagca aggctctatc
    96541 ctaataagat ccccttgttc aagcttgaga aaagcgagga tttccccgac atgatcgaag
    96601 ctgataccgt tcgtttggaa cgttgcctcc ggaatttgct agagaacgca ttgaaatatt
    96661 cgaatgacga tgtacgaatc accgtaacgt tgactatgaa aaacaaccat taccgaatag
    96721 ccataaaaga caccggttgg ggaatcccca agaaagccca gaaaaaactc ggacaacaat
    96781 tcttccgggt gaaacaagcc gacaagccag cgcaaccggg atatggatta ggtttgagta
    96841 gcgtaatgct aatggctaaa gaaatgggcg gctccctaac ttttcagagt gaggagggtg
    96901 tcggttcaac atttttcatt aacttaccag ccgaaaactc ataacactat atggaagata
    96961 aacagaaagt gatctttatt gaagatgacc caaaccttgg attaatcatc gtattggcct
    97021 tgcaaagtaa aggatacgag gtttgctacg ccaacacgtt aagcggtatt caagacatga
    97081 tagaaaaaga ctgccctaat atcctgcttc tcgatctgga agttggcaat caaaatgcat
    97141 tggattattt gccttttatt cgttcaaagc atccttcatt gcctgtactg atagcctctt
    97201 cccacaacga aggggaggaa ataacacgct gctatgaagc cggagctaat cattacacca
    97261 aaaaaccgta tgatatacaa gaaatagatt tcctaatcca aaggttttgt aaaaagggca
    97321 gtccgatatc aaatagtata tctattggag attaccaact ggaactctcc actcataaat
    97381 tattctataa acaagaacag tcaaaaacat taagtcctaa agatttcaag ttattctatc
    97441 tgttatccga gcaattaaat cagccagtaa gcagagaaaa gctttttcat gaaatatggg
    97501 atgggcaaga agttcatgat agcctaaaca acagcatctc gcgtttgcgc aaattattgg
    97561 aaaaagatac cacactttca atagatgccg taaaaggagt tggatatata ttatcaaaaa
    97621 aagaccaact ctcctcatcg taattaaggg gggcttattg tagatttcta gatacgccct
    97681 tgttccctat cgcatgattc gggaaaaaca cgtacgactt ttttgaaaaa cacctacgac
    97741 ttttccctaa aacacgtaca tgttttgagt aaaagatcat cctgttttta acatactaat
    97801 aatcagcata ttatataatt cttttcatta ccaaacttat tgtttggaat ttatatcgat
    97861 cctataggga cgtagcgtgc agcgtttgct acctaaagag ttttcattat cttcgcggaa
    97921 aattaattga gatgtggacg ttctttatca tacttccaat cctgtatctt gcagggaata
    97981 tttatattta tctaaaggga aaacaggctt tgaaaagcca gtctaccgga gttaaagtat
    98041 tgttatccat tgttttttgg ggaggagctt tatcattctt cagtagtttt ctattcagga
    98101 acctagatat gccggcttct ttcgctcaaa cagtttccca agtaggaaca ggatggctcg
    98161 tgttcacttt atacatggta ttagctctgt tggtatttga tatcttacga cttttccacc
    98221 tacgtttcaa atactcattc tatttatcct tattcttaac actcagctta ttaggatatg
    98281 gaaactataa ttaccaacat cctgatacac gagttatcaa catggttatc aacaaaccgg
    98341 ccaataccga tggacagccg ctgaaggtcg tagccattag cgacatacac ttaggatacg
    98401 ctaccaacaa gacaatgctt gccggatatg tggatatgat aaacgcccaa cgcccggaca
    98461 tcgttcttat cggtggagac ttgatagaca acagtgtcgc acctctacga tacgagcata
    98521 tggaagagga actgtccaag atctacgccc cattaggcgt ttatatggta ccgggtaacc
    98581 atgagtatat cagtggcata gaggagagcg agaaattcat agcgcagacg cccatcgtac
    98641 ttttaaggga ttccgtggct atcttgccca atcagatcca actcgtagga cgggacgacc
    98701 ggcataacaa aggacggaaa actttaggtc agcttaccgc gaaccttgat aaaagcaaac
    98761 ctgttatctt actagaccat caaccctacg atttagagaa aacggaagag gctggcgtag
    98821 acttacagtt tagcggacat acacatcgag gacaagtatg gccgatgaac tggatcgtgg
    98881 atcatctgtt cgaattaagt tacgggatta aaaaaatcgg aaatagtacg atttatgtct
    98941 catccggctt atctttgtgg ggaccgcctt tccgtatcgg aacggacagc gagatggtgg
    99001 tgttcaatat tacattcaaa gagtaaagat gaaagtattt attcaatcga tcgtagcgca
    99061 gctattacta aatccgtata ttttctggag aggatatcaa gcgcttcctc ctaagaaaag
    99121 ttgccggatt ccttttatct tgtttttcgt actcgaacta tcgctttatt ttttcggatt
    99181 tatttttagg aatgaactac ctgataacgt gataatcacg atccaataca tctgtaacac
    99241 ttggtatata gcgtccattt atatcacttt atctctcttg gtacttgagt tgatcaggct
    99301 ctcccaacgt atcaagccat ggttccccaa atggatgaaa gggcattggc agcaaaccaa
    99361 ggtaaccctg ttttttctta tcgtattcgg tgttaccggt ttaatgattc acgcatacca
    99421 tacggtaatg aatccgattg ttaagaacgt atatatcacg ttgcccaaag ccgcggggga
    99481 tcgggatagc ctgactattg tcatgatgag cgacttacat atcggagagg ttatcgggaa
    99541 ggacttggta caaaaatatg tggcgctcag caacgcacag catccggata tggtggtatt
    99601 agcgggggat atcatggatt atgaatcccg gtttgcggaa aacgcccaca tcgaggatga
    99661 tttaaaacaa ttaaaagctc cgttgggagt atatatcatt tacgggaatc atgaataccg
    99721 ggcaaaccgg aacgcgaaat atcgttggtt gcaaaagacc ggaggtacgc tactaataga
    99781 ctcggtggtc caaccggact caacttttta tttgataggg agggatgatt tcatccataa
    99841 gaaacgaaaa tcgcttcatt cgttaatgga aggggtggat accggcaaac cgattatcgt
    99901 tttggatcat caaccttggt cgttcgccga gatgaatatg aatggggtgg atttgggact
    99961 gcacggacat acgcataacg ggcagttatg gccttatccc ctactgatga aacttgtgta
   100021 tgaatgcccg tacggatatt ataagaaagg acctacgcaa ttctatgtat cttccggcat
   100081 tggtatagca ggacctcctt atcgggtggg aaccgtctcg gaattggtcg tattgcatat
   100141 ccgcttcaaa gcccccaaac agactggcga aagagggaaa agcacgatgc ccattcaagg
   100201 gagctgacaa tgggcatcgt aagctcgctt gaatgggcat tgtaaggccc tttgaatggg
   100261 catcggcaga aacccgccta ttcggtaccc ttggtggccg cttccaactc aaccggcacg
   100321 ctcaatgtac gcctgtataa atccggatcg cccaatacct ccaacgcttt ctccaataca
   100381 agatcatctt tcaagctttc ttgcaactct cctcgttggt aataataacg ttttacgatc
   100441 tcggcggcca ttactcgttt cacctcatcc ttgaaacgat cgaaatcttt ttccagattc
   100501 ggagtcagct tagcctctaa ttccttgaac gcagtagaat cctcctccag atacccctca
   100561 aactcagcca cttctttcaa gttcttcaat actttctcgc tttggcggtc ataggtgaaa
   100621 ttcttggact tggcgtattg cttcaaagct tcgaaatcct catcggaaac cgtaaattcc
   100681 tcgatgggag cgatcgtctt atgcttttgt acccaatccg taacgaagtc gaacaagacc
   100741 gtatccgccg ccaaataata catcatggta ggcactttcg gctccttcac ctcaaactcc
   100801 ggacgtacgc cacccccatc acgaaccgga cgcttcttgg acgtatagaa tacggaagtc
   100861 aagctatccg gaatagcagc cacgctacca tcctctttcc ggtgcgaata atcgatttgc
   100921 tggatgcaac gaccactcgg gatatagtat ttactcatcg tgattttcac tttcccatta
   100981 taaggcaggt cacgaggagc ttgcaccaac cccttaccaa acgaacgttg tcccaccaac
   101041 acggcacgat ccatatcctg caaagatccc gatacgatct cagcggcgga agccgtacct
   101101 ccattgatca atatagccaa cggcattacc gtatccaaag gctccgtaga ggttcggtac
   101161 gtacgatccc attgcttgat ctttcctttc gttgaaagca cctcgctgcc tttcggtacg
   101221 aacataccta cgatttgtac ggcaccttcc agcacgccgc cgccgttacc gcgcaaatcc
   101281 agtaccaaag acttaatatt atgatttttc tttaaatcca agaatgcctc tttcacctct
   101341 tgagcactct tgatagtaaa tgcctttaga taaatataac cgatactgtc attcttaacc
   101401 ccgtagtaag taacttgagg tgtcgtgatc tgcttacggg taatctcgaa cttccggggt
   101461 ttcttctcgc ccggacgttg gatcgtcaaa accatcttcg tattgggaac acctttcaat
   101521 aactcgctga cccgggagtt tgtcgccttg gaaacatcga tcgtatcgat cgccaagatc
   101581 agatcgcccg gcttcagacc cgctaaatcg gccggcattc cctcggtagg ctcggcaatc
   101641 atcacgcctc cctcattgtt acgctgacgg atcaaggaac cgatacctcc gtattcgccg
   101701 gtcgtcatca gactcaattc ctccgttttt tgctcaggat agtattccgt ataaggatct
   101761 aaaccagcca acattgcctc gattccccgc tgaacggttt tatccacatc cactgaatcc
   101821 acgtagaaca tctctacttc tttcaataaa gaattgaaaa tgtctaggtt cttactcacc
   101881 tcaaagcggt tatctttttg cgcccatccc ggcactacgc tacttgcgac gaacagcaag
   101941 caaaataaac ctataattcc tcttcgttga accaatctgt acatacaata tttagttaat
   102001 taacggcata aatgtaagga ataatacgcc gcctaagcca atatcccttt tacttttaac
   102061 tttatttgtt cccatttatc atacggaatc tccgggccaa ccacgtcgat cacatagccc
   102121 gccaacatcg atccgatgcg tgcggattgt accaaagacg ctcctatgga ttgaccgtac
   102181 aagaatccgg cggcgaagtt atcaccggcg ccagtcgtat caacaggctt gcccccctca
   102241 gccgggacag aataaaattg accatgacta ccgatcaagg caccttcctt tcccaaagtg
   102301 accaatgaga cctctaccaa ctcagacaag gtatgtacgg cctcagcagc cttctgcccg
   102361 gtaaaagact cagcctcact ctcattagag aacaaaatat ccacatattt aggaatgata
   102421 tcctccagca ttcctttaaa agcattcacg atattgaagt tcgacaaatc cagcgctact
   102481 ttcaagccca actttttagc cttctccatc gtagaacgaa ccaacggttc gtttacgagc
   102541 aagtaacctt ctatataaat acattgatat ttacttagca tctcctcggt gatctcatcc
   102601 ggggttattg tcggggccgg gccaaggaaa gtccccatcg tacgttcccc atccggagaa
   102661 atcatcaccg tacagctacc tgtaagtcca tccgtcttga taaaatagga agtgacaccc
   102721 gctttttcca acgcatcctc ataaaatccg ccgatcgaat catccccgat cttaccgata
   102781 aaaccggaat tcgcccctaa agaagacatc gaacgcatcg tgttgcagac agatcctccc
   102841 ggggtttgcg tacgtggcaa gccggctaaa gttgtacgga tagcgatcat ttgttccctg
   102901 ttaatcatat ccatagctcc tttctgtatc ccgatttccg ataggacatc atcattttca
   102961 agcctcaata aaacgtcaac caaagcgttt cctaaaccta ttgtattcat tttttcgtaa
   103021 tttttttcgc aaagatattg catatttcga aaataccc
//
LOCUS       DBMDTB010000002        97502 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_107_length_97502_cov_12.034065, whole genome shotgun sequence.
ACCESSION   DBMDTB010000002 DBMDTB010000000
VERSION     DBMDTB010000002.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 97502)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 97502)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..97502
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_107_length_97502_cov_12.034065"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..194)
                     /locus_tag="ACZPB4_00475"
     CDS             complement(<1..194)
                     /locus_tag="ACZPB4_00475"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1096739.1"
                     /translation="MFTHDMKNRVYIGPDISKQPTLTCVQTEIRLSLLGGTAEMSAVS
                     FFVYEPVTWLLTNRCLKIFF"
     gene            419..880
                     /locus_tag="ACZPB4_00480"
                     /pseudo
     CDS             419..880
                     /locus_tag="ACZPB4_00480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015546403.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage integrase SAM-like domain-containing
                     protein"
     gene            863..1864
                     /locus_tag="ACZPB4_00485"
     CDS             863..1864
                     /locus_tag="ACZPB4_00485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDDEXK nuclease domain-containing protein"
                     /protein_id="HIR1096740.1"
                     /translation="MKFEQNGEDRAAYGEQLLKKLEKRLNTKGLNERRFREFRRLYLV
                     YPQLKEEVLGYVISGSGIRRLPTAEFETEIRRSVTAKLQVVSEIANNDWKLAAEKLFN
                     RLSSTHLNAISAIDNPIKRAFYEMETIRGCWTVKELERQIDSLYYERSGLSKNKEALS
                     ALVQQQAVQLQPADVINTPLTLEFLGLNERALVTENDLEQAILDYLQKFLLEMGHGFC
                     FEARQKRILIDEDYFFADLVFYHRILKCHVIVDLKIDKFHHEYASQLNMYLNYFKTEV
                     MQPDDNPPIGILLCTEKGDTLVRYATTGLGPNIFVQKYKIQLPSEEEIKRFLSKEIG"
     gene            complement(1926..2726)
                     /locus_tag="ACZPB4_00490"
     CDS             complement(1926..2726)
                     /locus_tag="ACZPB4_00490"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008777733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIR1096741.1"
                     /translation="MKMDFKIRIAQQSDSAELRDLYKNTVLVVNRRDYSQDEVEDWAS
                     CGDDLSNIEEMIKTHYFIVAVNQLSQIVGFSSITPQGYLHSMFIHADFQGKGIATMLL
                     EEIERYAITKGIIQITSEVSLTARPFFEKQKYVVKKEQKRQANKLNLTNFWMAKTLSV
                     IKPYHGRIPACGVFCGGCPSYTRDEKNCQGAEENKTRCEKCRTFYLCCVEKGITHCYQ
                     CHLFPCTKFKGFTKRWLKYGQDFIENQKFLKQVGEMEFLRFYNEKVTD"
     gene            complement(2804..2989)
                     /locus_tag="ACZPB4_00495"
                     /pseudo
     CDS             complement(2804..2989)
                     /locus_tag="ACZPB4_00495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275262.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase"
     gene            complement(3020..3697)
                     /locus_tag="ACZPB4_00500"
     CDS             complement(3020..3697)
                     /locus_tag="ACZPB4_00500"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009016576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIR1096742.1"
                     /translation="MKYPIKTERLIIRLAEPEDAESIFSYRSDFAENKYQGWFPDSVE
                     EVRDYISNMPATMDIANICFQFTIILADENRLIGDMGISFTNHNNMQAELGCTLHKDY
                     QKKGYATEALKAIVDYLFGTLDKHRIIASVDPRNTASIQLIERLGFRKEAHFKESYYL
                     RGDWVDDIIYVQLKTEWGNNDKYSKEEIMIDPRIIALQFNECISRADINALSHPDTKE
                     NRNKFGI"
     gene            complement(3823..3906)
                     /locus_tag="ACZPB4_00505"
     tRNA            complement(3823..3906)
                     /locus_tag="ACZPB4_00505"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3870..3872),aa:Leu,seq:caa)
     gene            4110..5192
                     /locus_tag="ACZPB4_00510"
     CDS             4110..5192
                     /locus_tag="ACZPB4_00510"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009016577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004475 - mannose-1-phosphate
                     guanylyltransferase (GTP) activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009298 - GDP-mannose biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate guanylyltransferase"
                     /protein_id="HIR1096743.1"
                     /translation="MKDNYCVIMGGGIGSRFWPFSRESYPKQFLDFFGSGRSLLQMTF
                     DRFAKIIPTENIYIVTNESYADLIKEQLPELAEEQILLEPARRNTAPCIAYAAYHIKA
                     CNPEANIVVAPSDHLILKEDVFLRDVQKALDFVKRNRALVTLGIKPSRPETGYGYIQS
                     SDTVVDDFTKVKTFTEKPDLELAKVFMESGEFFWNSGLFVWNVNTILEAFSKYLPDIS
                     SRFDLGKDKFNTSEEKAFIQENFPYCLNISIDYGIMEKAHNVYMLCVDFGWADLGSWG
                     SLFDLANKDENENAVLKNNEAMLYECSGNVIALNNPKRLAVIQGLKDCIVAESGNVLL
                     ICKKDNEQRIKQFVADAKIKYGKEYN"
     gene            complement(5237..6466)
                     /locus_tag="ACZPB4_00515"
     CDS             complement(5237..6466)
                     /locus_tag="ACZPB4_00515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HIR1096744.1"
                     /translation="MNLPFYIARRYLFSKKSHNAINIISMVSVCGVVVATIALVCALS
                     VYNGFNDLVSSLFSNFDPELKIMPRKGKVFDPTSEEIRKVRELPGIVCFSEVLQDNAL
                     VRYRDRQGVATLKGVDEQYEKLAQIDSILIDGKFLLNDEVANYANMGIGLAFSLGINA
                     GFVSPLEIYAPKREEKVNMANPASSFNLEYAYIGAVFRTDQQVYDDSYMIVPLSLARS
                     LFNYDKEVTAVELKVKDSGDIAPVKKEIQRILGDQYIVQDRFEQQEASFKMMQVEKWM
                     TFLILTFILAIALFNVVGSLSMLMIEKQEDVSTLRNMGADDSLIRRIFLFEGWMISGF
                     GALIGVLIGVVLCLLQQEFGFIKLGEAAGAFIIEAYPVRVVPVDIITVFVTVLTIGFL
                     AAWYPVRYLAKKLKIEN"
     gene            complement(6478..6813)
                     /gene="rbfA"
                     /locus_tag="ACZPB4_00520"
     CDS             complement(6478..6813)
                     /gene="rbfA"
                     /locus_tag="ACZPB4_00520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HIR1096745.1"
                     /translation="MESTRLQKIERLLQKELSDIFQKQTQGMHGVLVSVSVVRVSPDL
                     SVARAYLSIFPSDKSQELLEAIRSNTKAIRFDLGQRIRLQVRKIPELSFFIDDSLDYI
                     ENIDNLLHK"
     gene            complement(6826..7461)
                     /locus_tag="ACZPB4_00525"
     CDS             complement(6826..7461)
                     /locus_tag="ACZPB4_00525"
                     /EC_number="2.1.-.-"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008171 - O-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HIR1096746.1"
                     /translation="MFTGEIDAYILSHIDEEGDLLSALNRDANVNLLRPRMLSGHLQG
                     RILKMFCRMIRPRRVLEIGTYTSYATLCMAEGMEEGALIHTIEINDEMEDFIMKYLSR
                     SLHKDKIKVHFGDAMEIIPRLDETFDMVFIDADKRLYSEYYDLVFPMVRPGGLILADN
                     TLWDGKVVEEVHPSDKQTKGILVFNEKVKQDDRVEKVILPLRDGLTMIWKK"
     gene            complement(7467..8924)
                     /gene="pyk"
                     /locus_tag="ACZPB4_00530"
     CDS             complement(7467..8924)
                     /gene="pyk"
                     /locus_tag="ACZPB4_00530"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0030955 - potassium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HIR1096747.1"
                     /translation="MLKHTKIVATVSDQRCDVAFVEALYKAGMNVVRLNTAHMMEEGL
                     TRVVNNVRTVSDRIGILMDTKGPEVRTTTTVNKEPIPFKTGEIVKVIGNPDQETSHDC
                     ICVSYKNFVNDLAIGSDILIDDGDLEMKVIGKSGDCLLCDIQNDATLGSRKSVNVPGV
                     RINLPSLTEKDRNNILWAIDHDLDFIAHSFVRNKQDVLDIQRILDERNSPIKIIAKIE
                     NQEGVDNIEEILEVAYGVMIARGDLGIEVPAEKIPGIQRMLIRKCVEVKKPVIVATQM
                     LHSMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGKYPIEAVQTMTKVAREAEKT
                     KLSANDIRVPIEGNDLDVTSFLAKQAVKSSSKLHVKAIITDSYTGRTARYLAAFRGTS
                     TVFAICYNPRVMRMLGLSYGVWAVHQPYNDSRRGYFYDALNQLIHSGRITRNDMVAYL
                     SGSFGEGGGTSFLEINNVGKVLDAGTQYQLPTFKE"
     gene            complement(8985..9401)
                     /gene="aroQ"
                     /locus_tag="ACZPB4_00535"
     CDS             complement(8985..9401)
                     /gene="aroQ"
                     /locus_tag="ACZPB4_00535"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II 3-dehydroquinate dehydratase"
                     /protein_id="HIR1096748.1"
                     /translation="MKKIQIINGPNLNLLGKREPTVYGNASFEDYLSELRARFPQCEI
                     SYYQSNVEGEIINKIHEVGFEYDGIVLNAGAYTHTSIALHDAIKAVTTPVVEVHISNV
                     HARESFRHVSMISAACRGVILGFGLDSYRLAIESFM"
     gene            9503..10408
                     /gene="xerD"
                     /locus_tag="ACZPB4_00540"
     CDS             9503..10408
                     /gene="xerD"
                     /locus_tag="ACZPB4_00540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009009 - site-specific recombinase
                     activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HIR1096749.1"
                     /translation="MRQGKDIINRYNTYLRLEKSLSANSIDAYLTDLDKLLRFAEDEK
                     KDVKEISYDDLQQFIAQLRDIGIHPRSQARIISGIKSFYRFLLLDNYITNDPTELLES
                     PKIGLKLPEVLTVNEINSILDTIDLTLPEGQRNRAMLEVLYSCGLRVSELTGLRYSDI
                     YPKEGFIRVEGKGSKQRLVPISEVALREIKNYLYDRNSVVVKKGFEDILFLSRRGTAL
                     SRIMVFHIIKQQTEAAGIHKNVSPHTFRHSFATHLLEGGANLRAIQEMLGHEKITTTE
                     IYTHIDREFLRKEILEHHPRSRPRT"
     gene            complement(10448..11344)
                     /locus_tag="ACZPB4_00545"
     CDS             complement(10448..11344)
                     /locus_tag="ACZPB4_00545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HIR1096750.1"
                     /translation="MEKKTEKEEKYMKELQDRYIRFDWAIKRLLRQKANFGVLEGFLT
                     VFLGEQIKIEEILESEGNQQDADDKFNRVDIKAKNTKGDIILIEIQNTCELYYLERVL
                     YGMAKAVTEHLHLGQDYSGVKKIYSISILYFDIGVGTDYLYHGQNQFVGVHTHDHLQV
                     NTKERGVIVKRLPSEIFPEYILVRVNEFDKEAVTPLEEWVRYLKDGIITSETTAPGLE
                     EAREKLRYYSMSPEERYAYDEHLNAIMIQNDVLSTAKFEGWEEGRVEERLETARRMRS
                     DGLSMEMVVRYTGLSEEEINNL"
     gene            complement(11677..13182)
                     /locus_tag="ACZPB4_00550"
     CDS             complement(11677..13182)
                     /locus_tag="ACZPB4_00550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RagB/SusD family nutrient uptake outer membrane
                     protein"
                     /protein_id="HIR1096751.1"
                     /translation="MNKYIYLLAVVFGLSSCNDFLELSPTNKVIETDYYKTQEDLTEA
                     LVAAYDPLKWNAYNAYSSYELVSNIMSDDAETGGSTVSDQPQLQRVNDFTNWVTPTNL
                     PEGLWGRSYEGVNRANIVIEKCPLLPEGTMSAELRDRYVAEAHFLRVFYYFQLWRFFG
                     YIPYYETNLGLDDITTVPQLQPDEVYAKLIEDLDNNVIGKLPKVVPANEKGRATNGAA
                     IAMKARIVLYQNDDTKMKEIASQLKELITDPAYQYDLIPDYKVLFDDEYEWCKESVFE
                     VNYTEIGNSNDWAGKANQGNSDIIMLGARGLKDPNNVYVEGWGFAPVTKALNDAFLPD
                     DPRKWTTIIDHEEFRAEGGTISSDVNQYTGYSVRKYHPRAGYSSTVGTEALNYKNNYR
                     VIRFSDILLMASEALLRSGGSVGEAQDYYARVVKRAMGDDYKVPTVSLDNIYKERRYE
                     FAMEGIRYWDLVRTNQAKDFIKGWDDTKKYLPIPQSEIDKSDGHLVQNPHF"
     gene            complement(13200..>15586)
                     /locus_tag="ACZPB4_00555"
     CDS             complement(13200..>15586)
                     /locus_tag="ACZPB4_00555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="SusC/RagA family TonB-linked outer membrane
                     protein"
                     /protein_id="HIR1096752.1"
                     /translation="KMSVLNATEYETIMNEAYVNAGMDPIYDDPSKAGVGTNWQNEIY
                     NENAPIMNHQASISGGGDKGSYFLSFGYLDQEGIVGGKDKSDYKRYSLRFNNTYNVFE
                     NKTNKFFRSFKVGTNLGYTRIISKGISENDNFSGPLASAVMTPPNESVYLENPSAEDL
                     AYYEKNYPGYVKDDEGRIYNVIENQEIVNPVAMMQTLNNNKDWDKFVGSVWGELEVFE
                     NLTFKTSLSTDMAFWGERNWFPVSYLCYMVKNEKSRVEQTMNRGMKLLWENTLSYKRS
                     IDKHNFAVLLGTSMERYDSKKVKGTALNLRAEDDHKAWIDFTNSASPGDQHSEGGATE
                     HRMASVFGRLNYNYDERYMLELTLRRDGSSNFGRNNQYAYFPSVSAGWTLTNEPFMEN
                     KPGWFDFLKVRGSWGQNGNEKIGSFGYTTTMTGGNNYSFGVSSNGVIHSGTKPTSLAN
                     PDLRWETSEQLDFGFDSRFFNNSLSFSFDWFKKDTKDMLMERPIPLYVGSGSPLSNVG
                     TLTNQGIELEVGYKLSVDKVNLSFLANASYVKNEIKNLGNQTGYIDKESLPTLGTVSR
                     NENGYPIGYFFGYKAIGVFQTQEEIDSYISPATGKPIQPNAAPGDTKFEDLNGDGVIS
                     DDNEDRTMIGKPNPDWMVGLTVAADWNGFDLSAFFQGSFGADVFDALRRYELAAVNYT
                     SDALERWTGPGTSNSMPRIVLGDTPKNFRPSTLLVHDASFLRLRNLQVGYTLPAQLTR
                     KAYIQRLRFYASFDNLLTITGYKGMDPEIGSTMGIDKGVYPQARVYTFGLNLTF"
     assembly_gap    15587..15686
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(15882..18122)
                     /locus_tag="ACZPB4_00560"
     CDS             complement(15882..18122)
                     /locus_tag="ACZPB4_00560"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2 protein"
                     /protein_id="HIR1096753.1"
                     /translation="MKRIILIMCCFLSVFAWADDGRTTISLNGEWDFDQTEHAFPPRK
                     YTRKIPVPGLVHLARPKISQYEKFFKKPDGVELVEQFNFLERDYTPMYNWYKRKVFID
                     EKFKDEQLFLTIKKSQYVTRVFVNGHQVGSSMECYTPMDFNITSAVKYGSDNEILIQV
                     GDRAWLPSEAAGGTDKEKVHYLPGIWDDVFITATGKMRVDKILFLPSLAKGLVTVKTL
                     VRSLYPPQMLYGDKMKDSCKIEFCVKEKTTGQVVGKKVIEGEVKRDNRTYFETSISLD
                     NPKAWTPDSPFLYEGEVSVYDQDELVDRYSVNFGMRDFSRKGKFFTLNGDKFYLRGSN
                     ITLQRFFEDPDCQALAWDREWVKKLMIDLPKSIDWNAMRICVGIVPDFWYDLCDEYGI
                     VLQNEWLYWQNHGWDEQVRKEYTNWVWSDGNHPSIVIWDAINENWDSYIGNTLIPELK
                     ELDPTRIWDAGYMTSDQMGTNDEMDEPHPYRALTLMHSSELNDYFKNNPYNLGALHEN
                     WVGFSSILDAGVPQLVNEYGWIWLWRDGRPSKLTLNNYNYYLGENATPAQCRELQAYW
                     LQLETEWLRSERSVGGILAFCHLTNNYGFTGDWFINDIKDLQPSPAFRWFKHCFAPTA
                     VFIDLTDHRYTKHLPALKPGSDLVFNLVGVNDLNKDSSGKVLLKLLDEKGTIISTQEE
                     SIVIEPFGKRLQPCLLKLPSKAGGYLLIAEYHEKGGAKPVLSRRYLKVGDAVTSFKDY
                     FEYTLN"
     gene            complement(18257..19516)
                     /locus_tag="ACZPB4_00565"
     CDS             complement(18257..19516)
                     /locus_tag="ACZPB4_00565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulase-like family protein"
                     /protein_id="HIR1096754.1"
                     /translation="MDRRVFIRQTAVAALGGLVAFDLSNALAKSEMAFAGKGEISPRA
                     ITMWDFSWLERRWPGAGYEDWDQVLDELSERGYNAIRIDAYPHLIAENPMKKWLLKEV
                     WNQQDWGSPDMNEVQVQPNLNLFLSKCKERDIKVGLSSWYRLDVDEVCLKLDTPEKLA
                     DCWLTTLRSIEEDGLLDTILYVDLCNEWPGDSWAPFFAKTYPNVGWGNWYKEESLRWM
                     KTSLEKMRQVYPDMPFLYSFDHGDVKKYEEVDCSFLDLYEHHIWMAQQNGGEFYKLVG
                     YGYNRFLPDDYKNVVKNAERVYRERPGYWQKLLTDKIELMASVARKNRRPLVTTECWG
                     LVDYKDWPLLKWDWVKDLCELGTITAARTGMWVGVATSNFCGPQFAGMWRDVEWHKRL
                     TSIIRSSPLDESLTKNNEVAAKLLKRL"
     gene            complement(19518..20955)
                     /locus_tag="ACZPB4_00570"
                     /pseudo
     CDS             complement(19518..20955)
                     /locus_tag="ACZPB4_00570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772978.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0051119 - sugar transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
     gene            complement(20988..21776)
                     /locus_tag="ACZPB4_00575"
     CDS             complement(20988..21776)
                     /locus_tag="ACZPB4_00575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009016584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase family protein"
                     /protein_id="HIR1096755.1"
                     /translation="MNGFVFDKGIDITPVQSPMGFTYGAGVFGPEVEIRRLEDIRASL
                     RDPQCKGPEQVYSIAMDVGKEEHRVLLNKLHLLFGVVTYSAGKLGQEPVRSQGHIHKI
                     SPYSGWSTPEIYEIWSGEAIIYMQEYAEDQPGRCYAVHAFPGDVVIVPPYWVHVTISA
                     NPRLPLTFGAWCDRDYGFVYEGVRKHGGIAWFPIFNGSDELEWIANPMYDSSHLICKS
                     PSDYISLDIRKGVSIYRQFEENPEIFLYVPNPALKAEVWRDFEP"
     gene            complement(21757..22716)
                     /locus_tag="ACZPB4_00580"
     CDS             complement(21757..22716)
                     /locus_tag="ACZPB4_00580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HIR1096756.1"
                     /translation="MYTIAIDLGGTVVKIGLLSDGEIVDCVRLPSRLALGLALNLPKI
                     KEAIDRLLAAWRIDVAALRCIGLAFPGLVDPIHNRVISTNEKYDDACSISLDKWAWEN
                     WEVPFCMDNDARLAVAGEWWQGAARGKNNVVMMTIGTGIGTGVVIDGRLLYGQHFQAG
                     SLGGHFVLDYKGRRCSCGNKGCVEALSSSFFLPTIIREHALLSESFKRDADIYDFKRI
                     FRLAQEGNTDALLIRNECMDIWASAIITYIHAYDPEVVILGGGILKSQEVIIPYISKR
                     VDELAWCPSGKVPVVPAILGDDAALFGLEYFMVKQQQNERICI"
     gene            complement(22720..23277)
                     /locus_tag="ACZPB4_00585"
     CDS             complement(22720..23277)
                     /locus_tag="ACZPB4_00585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009016586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HIR1096757.1"
                     /translation="MEHKKIVIPSLSFFQNELKGEGVVKSRRTLGELAGIFENQDAYS
                     QLPLDQLAYEVYSYLPEREGTPGGLYFGITQLYPGKVGDEYFMTKGHFHQQEDRSEYY
                     WGLEGEGMLILMDRERNTWAERMMPGSLHYILGGVAHRVANTGNSVLSFAACWPSDAG
                     HNYEEIANKGFSARLVEVNGTPKLR"
     gene            complement(23375..24256)
                     /locus_tag="ACZPB4_00590"
     CDS             complement(23375..24256)
                     /locus_tag="ACZPB4_00590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HIR1096758.1"
                     /translation="MKPLFQELPFPIDSHIHFYVEDLPHFIVPWHYHPAIEIMYITSG
                     TGTRFVGDHVEGYFEGDVCMIGPQLPHEWRNDPVYFDKSSGLRATCICLFFKRQIFEP
                     NLIRLPEMNNIRELIERSRRGIKFVGKSRKKIAELISQSANETGASRVIKLIALLELM
                     ATSEEYEILASTGFTETVNSDDFERFNKVYKYLVKNFTSPVKLEEVAALVGLTPTAFC
                     RYFKKRTKKTFVEYLNDMRIGHAKKLLIEGNLKISTISSEAGFNNLSNFIGQFKKTTN
                     MLPSEYQKKYKERLDGE"
     gene            complement(24262..26250)
                     /locus_tag="ACZPB4_00595"
     CDS             complement(24262..26250)
                     /locus_tag="ACZPB4_00595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4954 family protein"
                     /protein_id="HIR1096759.1"
                     /translation="MNHLRNLRPDEIATLRSQACRADDWNQVWVPEVFDIEYVNHVRF
                     SGVVRLGAFRKVFTLPGGLVKHSGLRHVTLHNCTLGDNVLIENVQNYIANYRIGDDCF
                     IQNINVMLVEGKATFGNNVEVSVLNETGGREVPIYDGLSASLAYIIALYRHRPALIER
                     LRDMITAYTEGIASTEGTVGDKVKIVNTGTIRNVKIGDYATIENSARLENGSVNSKRE
                     APVFIGDSVIAQDFIVSSGAKIADAAKIIRCFIGQACQVTHNFSAHDSLLFSNCAFEN
                     GEACAIFAGPFTVSMHKSSLLIAGMYSFLNAGSGSNQSNHMYKLGPIHQGIVERGSKT
                     TSDSYILWPARIGAFSLVMGRHHHHSDTSDIPFSYLIEKDDETYLVPGINLRSVGTIR
                     DAQKWPKRDKRTDPDRLDMINYNLLSPYTIQKMLKAVDILKNLQALVGETSEIYYYQN
                     TRIKGSSLRNALNFYGMAINKFFGNSLIKRLEGTTYCSMEEVWEQLRPTESKGSGEWL
                     DLAGLILPREPLDALLQDIEQGEIASLEDVECFFRLVHGRYYSLEWTWAYEMIERYYG
                     VDLRSISAAEIIDLVRRWQECVIRLDEMLYEDARKEFSLTSMIGFGVDGSNKEKQQDF
                     EGVRGDFVNNPFVTAVQEHIVNKRALGDELIERLKPLV"
     gene            complement(26272..27483)
                     /gene="hflX"
                     /locus_tag="ACZPB4_00600"
     CDS             complement(26272..27483)
                     /gene="hflX"
                     /locus_tag="ACZPB4_00600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008156566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HIR1096760.1"
                     /translation="MKEFIISEAQTEKAVLVGLVTPEQNEQKVKEYLDELAFLADTAG
                     VDAVKRFTQKMDYPNSVTFVGTGKLQEIKEYVVENEIGLVIFDDELSPKQLRNIEKEL
                     QVKILDRTSLILDIFASRAQTAHAKTQVELAQYKYMLPRLTRLWTHLERQRGGVGMRG
                     PGETQLETDKRIILDKIARLKKELVDIDKQKSVQRKNRGKMVRVALVGYTNVGKSTLM
                     NLLSKSEVFAENKLFATLDTTVRKVIIENLPFLLSDTVGFIRKLPTELVESFKSTLDE
                     VREADLLVHIVDISHPTFEEQIEVVNRTLAEIDKTEKPMIMVFNKVDAFTFVPKEEDD
                     LTPRGRENIDLDELKRTWMGKLQDNCIFISAKERTNIEALKEMLYERVKQIHITRFPY
                     NDFLFQQYDEE"
     gene            27557..29359
                     /locus_tag="ACZPB4_00605"
     CDS             27557..29359
                     /locus_tag="ACZPB4_00605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="T9SS type A sorting domain-containing protein"
                     /protein_id="HIR1096761.1"
                     /translation="MKKRIWHLSRRVVVCTVFLFVQQFIQSQVSNPSTWESFVQSNAN
                     ISIRDTFRMQTFEGLASDNWDYAITGEALIEDISGVKDIPNSHGNYGLRMPMNTQAAF
                     EHFTLTDHQDIKISIRKGGIHLMLGEKMQVKTYRPNKPEYVSIITLNKDDATASFEKT
                     DIGSNPPGLDIIVPTQAANTKNGYYYVDSVYAHGMIPTYSLFTGNSDWNHEDRWSHLP
                     AYRHRNALINGNISINTNISCKDIFIGNGNIHILPTGNLSANNLTIYPNDGILASSST
                     LRSSGTINISGKITIEKTFAQKGKWYFISFPFDVFASGIDPDFQLGDDKSDTNGNYFY
                     VQTYNGEKRANSQSPSNNWEVIPQTIINTSQPIFKKNKGYLIAIDASADRQNLRFSSK
                     AGDIPIDFGKNGQASIPVSINNQSQNQNHNGWYLCGNPLPAPLSLSQIESNSALDGYI
                     YIYDGSTYQPYVIGSDFAIPPFSAFFVKANKSTSLSVYNTSEPANYKLLSTNAPISFP
                     TSEPQAQQDSPVSNQVFSFPELSYQLENKTLFITNLPSPGKVELFTPAGILVFTQAVQ
                     AGNPILPIPLPQGLYILIIQTEHYRAQYKCVLTS"
     gene            29409..29627
                     /locus_tag="ACZPB4_00610"
     CDS             29409..29627
                     /locus_tag="ACZPB4_00610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1096762.1"
                     /translation="MKKINITTIALLVYLIVMSIIGWPGNNPGNSYTEYFLMIGATLV
                     IIILLRYLQVKRLRMRDKWNKDDDPAKQ"
     gene            30064..33252
                     /locus_tag="ACZPB4_00615"
     CDS             30064..33252
                     /locus_tag="ACZPB4_00615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SusC/RagA family TonB-linked outer membrane
                     protein"
                     /protein_id="HIR1096763.1"
                     /translation="MDNRNYFTMAIPALLLGVAYLQPINAAPAEDLPNVTGRMTITQQ
                     TFTVSGVVTDTNGEPIIGANVIEKGTTNGAVTDFDGKFSLSLQNKQSILVVTYIGYNT
                     KEIPAGNGSPLTIQLQDDTQNLDEVIVVGYSVQKKKDLTGAVSVLEVGDLKDTPVSSV
                     DQMMQGKLSGVNVIPDNMPGGGVAVRVRGFSTIRNNDPLYIIDGVPVEGGINFLNPND
                     IESMQVLKDASSASIYGARAANGVVIISTKKGKEGTFRVNLDAYVGVQTSAKQMRMLN
                     AQEYGDLLWQAQRNDGKSPVSDVYGSGETAVIPEFLDADHRLPSGDVDWVDEIMQKAM
                     VQSYNLSLAKADKVSSHLFSLGYFNQDGLMKYTGFERISGRFNNEFKLFNDRLKIGEN
                     ATLSHAWGTSVTNNAALGGMLYNAYKTVSITPVYDLDGNFGSNPIADISNPLGELYRN
                     KDNKDRTTRLFGNLFAELNILEGLYFKTNFGADYKNLYKRSFKAKYNELNTQQPLSTL
                     STQNRWNFNWVFTNTLNYLRTFDKHTIGALLGIETNRYQEEYFSASREGFASDDDNFH
                     FLDAGDSGSQKNAGSAFTSKMMSYFGKIDYNFDNRYLFSATFRRDGSSKLGNNKWGNF
                     PAVSAGWRISSEPFYDIPAISNMKVRIGWGQNGNSDIPAYSTIDSYMSNPNHSNYPID
                     GSQSSVTTGYTQTRYGNANLKWETTTQTNVGLDLGFLDNSLTVVLDWFNKDTKDLLWE
                     RPLIGTVGGTNQTVWDNVGKMRNRGFEAEVSYNKSINKDFGFNVAFNMSAIKNKMTEL
                     DGDVSYIGLPTSVIHSLNFDQEVSRSAIGQPIGSFYAYKEDGLFQSEAEIKSYTNNKG
                     ELLQPNAKPGDIKFVDVNGDGVIDGNDRDYIGNPLPDVTAGLTLGVNFHNFDLSLFFQ
                     GMFGNDVYDLTRYVGDFYNQSQYNKNSRVVNAWTPTNTNTDIPRVTMDDPNNNIRPSS
                     YYVQDASFVRLKNMKIGYSVPQSILSKIKFNSLYIYAQATNLFTITGYDGIDPEVGLQ
                     SYSSDYRNLDMGVDRGIYPLSRTFTFGVNVSF"
     gene            33278..34909
                     /locus_tag="ACZPB4_00620"
     CDS             33278..34909
                     /locus_tag="ACZPB4_00620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RagB/SusD family nutrient uptake outer membrane
                     protein"
                     /protein_id="HIR1096764.1"
                     /translation="MKKMIIAACAVFALTSCSDFLEETPVGELTPEQAQDPNNIEGLI
                     ISAYSILDGQMDDASSGLNSGCSNWQFGDVISDDTYKGGGGTGDQNPIHLMEIFHIDP
                     TIQDYNRKWLALYEGVNRCNQAIRILKGSDYDKKETRIAEMRFLRAHFYFNLKIIYNQ
                     IPYFDESVSDPSAFASISNKEYTSDQLWEKILNDFKAAYEGLPDSQPDVARPCKMTAR
                     AYMAKVYLFQGKWQECATATDEVINSGKYQLLPDFRNIFLPENDNCPEILFSVQASIN
                     DGSPNNYNGNPGDRLLPPGGPYPNYGFLRPSQNLVNAYKTDSNGLPLEDGIDVSENDY
                     VDTRLDHTVARPGIMFLDVQLYDWTPREATVYGPYSPKKRIVSKNSSYYLAIWPYVNA
                     LNVYIIRYADVLLWRAEAAIELGDLATGLKYINQVRERAMNSQTVKTADGTADAAKYR
                     IGLYPSFSDKEEAIRALRTERRLEFALEGERFFDLVRWGIASDVMNTYFEHEKTFRSH
                     LQNARFIKGTHEYGPIPQAVIDLAKNGIIEQNPGY"
     gene            complement(34998..37781)
                     /gene="uvrA"
                     /locus_tag="ACZPB4_00625"
     CDS             complement(34998..37781)
                     /gene="uvrA"
                     /locus_tag="ACZPB4_00625"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HIR1096765.1"
                     /translation="MSESNSIFIKGARVNNLKNIDVEIPRDKLVVITGLSGSGKSSLA
                     FDTLYAEGQRRYVESLSAYARQFLGRMSKPECDYIKGIPPAIAIEQKVNTRNPRSTVG
                     TSTEIYEYLRLLYARVGKTISPVSGTEVKKHQVSDIVKEVMRYPEGTRFAVFAPVVLP
                     EGRDMKEQLEILRKEGYARLSVNDTVYRISEVLASEELLSYPIELLVDRLTVSDDKTL
                     KSRLADSAETAFFEGHGTCLIRIYTEEGVVVKEFSKKFEADGMIFEEPTDMMFSFNNP
                     LGACPTCEGFGKVLGIDENLVVPDKSLSVYQGAVVCWKGEVMGEWLKDFIVKSEKYNF
                     PIHRPYYDLTQKEKDLLWHGARGLHGIDDFFKFVEENLYKIQYRVMQARYRGKTTCPV
                     CKGSRLRPEALYVQVGGKNIAELVTMPVSEAKAFFDQLELDETDAAIAKRLLTEINNR
                     LQFLLDVGLGYLALDRLSASLSGGESQRINLATSLGSSLVGSLYILDEPSIGLHSRDT
                     DLLIKVLRQLQALGNTVVVVEHDEEIIRAADYIIDIGPKAGRLGGEVVYQGDVNNLRK
                     CTDSHTVRYLTGEDQIEIPPYRRPWNNYIEVTGARKNNLKGVDVKFPLNVMTVVTGVS
                     GSGKSSLVRDIFYEGVKRHLDDAARLTVDCSGISGDLNMIQAIEFVDQNSIGKSSRSN
                     PVTYIGAYDEIRKLFGEQPLAKQMGYNAAYFSFNKEGGRCEECKGEGKITVEMQFMAD
                     ITLECEACHGKRFKQDVLDVEYQGANIYDVLEMTVNQAIEFFEKGSGSQEKKIVKRLK
                     PLQDVGLGYIKLGQTSSTLSGGENQRVKLAYYLGQEKQQPTLFVFDEPTTGLHFHDIK
                     TLLKAFNALIEKGHSVVIIEHNMDVIKCADYVIDLGPEGGKAGGQLVCAGTPEEIAAC
                     EASYTGRFLRDKL"
     gene            37988..39517
                     /locus_tag="ACZPB4_00630"
     CDS             37988..39517
                     /locus_tag="ACZPB4_00630"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 10 protein"
                     /protein_id="HIR1096766.1"
                     /translation="MYIKYFRFLVAILFCAITSCSTVREKPRPATSTGKEAKREFRGA
                     WIQTAFQGEYKDMTPARMKKDFIRKLNYLQACGINAIIFQVRPEADAFYKSDIEPWSR
                     FFTGEQGVAPAGEFDPMAFLIQECHKRNMEFHAWLNPYRASTAGNTRFADSHIYHKHP
                     EWFVTYNKQILFDPGLPESRQFICRVVRDIVGRYDVDAIHMDDYFYPYPVAGMPFPDD
                     NSFRKYGLRKGYSEAQRNDWRRENVNTLIRELKRTILLTKPWVRFGISPFGIYRNKKS
                     TADGSGSNTNGLQNYDDLYADITYWVQQGWIDYNIPQIYWEIGHPAADYITLIKWWDK
                     NANGGHLYIGQDVARTMKADQLTRKMRYERALPHVSGNCFWPANEILWNNKGVADSLK
                     RNYHRYPALIPAYTHMHNRPPKDVSKLKTEWTPKGFLLHWQAEQSPTNPELASYFVVY
                     RFNDKEPIDTSDPSKIVAITRETGYLMPYEKGKVKYRYVVTAVDRFHNESEGKTKKVK
                     L"
     gene            39529..40383
                     /locus_tag="ACZPB4_00635"
     CDS             39529..40383
                     /locus_tag="ACZPB4_00635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HIR1096767.1"
                     /translation="MLTDHRCTKYTDCSSCGFYQRDIFKYRLYPKGYVIPQTRCMQNM
                     VFFLIKGEIWLNSEEHPDTTFRGGQFVLQPIGSKVECKILDYTECIIYLFERPQNICD
                     NRFNKGISIVENERQQPIVMTMVPPIQLFIEGMKLYLNDDLRCSGLMQAKRSEMVYLL
                     NCYYPIKELAAFYAPIYRYSHSFQYFVMQNYQKAKDVETFAQLGGYSVPTFRRIFKDT
                     FGEPAYQWMLKRKCQDIHNDLIMTELSISEICYKYGFESLSNFSHFCRANCGQSPRSI
                     RSLKDENT"
     gene            40516..41427
                     /locus_tag="ACZPB4_00640"
     CDS             40516..41427
                     /locus_tag="ACZPB4_00640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5119 domain-containing protein"
                     /protein_id="HIR1096768.1"
                     /translation="MYRYNKTSIILKITIAILFITSLVIECSCERSDEPKKESTGFIT
                     YTLRWDSVIPGFPAPEKLRYCIYPSEGGPMIQTDGDANSMMLFLPPATYKILVFNYDA
                     KNIDFRNMSRFDEAEAYILQTKATGQASQGITPLYGFVVDSLEITPGQDKSGTLVLTP
                     LVRHVTFTVQVDKPEEIKTCKGSLSGVSTSLNLSKRKVVTEASTNVEFDMETSDKGVN
                     GDLIILGTALPKEEEQKPVTNQVTIDFTLSDGSMVSATADLEDKLNEIDTPHVNVTIN
                     ATVEKSPKFTIRLTNWEVGPGEETTIE"
     gene            41472..42452
                     /locus_tag="ACZPB4_00645"
     CDS             41472..42452
                     /locus_tag="ACZPB4_00645"
                     /inference="COORDINATES: protein motif:HMM:NF024548.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrillin family protein"
                     /protein_id="HIR1096769.1"
                     /translation="MKKLMISMLAMAAMVSCTNEIENPDQPQVNQNEPTPIEFGSSIL
                     GVQTKAAPGETAEAFDVGEIMGITMYLGEVPTGASLGTPSKDNVSFTVGSDNKLSETA
                     TENKTMFWKRGSKHQFYAYYPRIADDTNANYKRTAASGSNAEKITVTVPTTGETTDLL
                     MGKLELTSEYEGTAPSPANIGFKHMLSKIKFVFKKDASYTGEAKLTNISVSLDKGSKV
                     FDMVAQTGDATSASPVTITKASTYTIIENADGDIYTDWSPIVIPEASITNLSLTIDGQ
                     TLSTTSFGSLSFKESKMTTLTITLTSSNIELTSSITAWADGGTNGNATVK"
     gene            42582..43538
                     /locus_tag="ACZPB4_00650"
     CDS             42582..43538
                     /locus_tag="ACZPB4_00650"
                     /inference="COORDINATES: protein motif:HMM:NF024548.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrillin family protein"
                     /protein_id="HIR1096770.1"
                     /translation="MYEYEHSTPIKFSSSCINVSTKSQGIIENNKLPKGSNISIFSIQ
                     HPENTTINLWEPILFDNIKGISNFNGDIEYNNTYYFPDKEQLDFFAIYPFLSFPTIGS
                     DYGNTQYTTVTLKDNTVDQYDLMYASLLNQSKKSSVLVFEFHHLLTQITINIIKNTGV
                     TIDLPLTKVQIVAPQSATLDIWHGQLSDIAGQTTYTLDTNTTLSNGDNSIPGQFLLFP
                     QKANEMILTFGNDESNVFHVALSDEPRTWEAGVNYQYDITINRNIPEITSPEVPVDDN
                     ATPNEEVNNGGEIPETPTDSTATASQTKASGPNPYHIHLSID"
     gene            43566..44498
                     /locus_tag="ACZPB4_00655"
     CDS             43566..44498
                     /locus_tag="ACZPB4_00655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrillin family protein"
                     /protein_id="HIR1096771.1"
                     /translation="MRYTKQLITVSLLMGLSLNSCTNDDNSVPSQQTPTVILFSASPY
                     RLESKAIHTESTMPTDLPIGIYGWGHKLGQTAPLTPRPDLTNQAYTTTDGTAYTSDMD
                     AHFPVASDTVIDFYAYYPYQASLSNSEASYDLKDQIDIMYATPILNKGKMDVETDTNS
                     STATATVALTFNHQLSAITIVIKKADDIKEPLILQKVELVNYPSSIHMNIQTGRLTAS
                     NTVADYPIPLAAPITITPAEATVSTNYLLWPGEAPTFRFSISDHTYEVHPSQAFIAGK
                     KQKYTFTIQAEDINVGASINPWTEGPEGSGEIGI"
     gene            45382..45792
                     /locus_tag="ACZPB4_00660"
     CDS             45382..45792
                     /locus_tag="ACZPB4_00660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1096772.1"
                     /translation="MKTILLLPVLSLWLLLATQAHAQVYHLHLSDNTCRITECVDTPQ
                     GIKPLGQTWKGNTFHDRFTLDFDRAIFTWEKEGKETYANKIINHTAKYAHHSFTTEQI
                     TANLTINSHRAVLQLIHFQNGQWIQVTYFCEIGN"
     gene            complement(45887..46615)
                     /locus_tag="ACZPB4_00665"
     CDS             complement(45887..46615)
                     /locus_tag="ACZPB4_00665"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HIR1096773.1"
                     /translation="MNLDEVLHHRRSVRVYDKEKPIDTEKVKHCLELATLAPNSSDMQ
                     LWEFYHITEPELLAKISRDCLGQKAASTASQIVIFVVRRDWYKKHARFVLNFERENIR
                     HYSPKERQAKRIKDREIYYGILMPFVYARFFGILGLLRKLLANIISIFRPMMLEVSEN
                     DIRVTAHKSCALAAQTFMIAMANEGYDTCPLEGLDSRRLKRTLKLPHGAEINMAIPCG
                     IRDGNKGIWGERCRVPFEDVYRKL"
     gene            complement(46671..47360)
                     /locus_tag="ACZPB4_00670"
     CDS             complement(46671..47360)
                     /locus_tag="ACZPB4_00670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019172 - glyoxalase III activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HIR1096774.1"
                     /translation="MKILIIVTSTGTFANGKLATGLWLSEFTHIYHSAKESGYDITVA
                     NPKGGYTPIDPESLKPIFLDEMSEKYWEKPEFKKLLDHANSLDNLLEQQFDCVYLAGG
                     HGAMYDFPGNEALKTIVRKQDESGRIVSAICHGVSGLLNAKLSNGEYMIKGKKLTGFS
                     WFEESLARRKEEVPFDLEALLKERGADYEKALIPMTSKVVVDNNLITGQDPFSSKEMA
                     KVVMRQLNKAQ"
     gene            47577..48050
                     /locus_tag="ACZPB4_00675"
     CDS             47577..48050
                     /locus_tag="ACZPB4_00675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HIR1096775.1"
                     /translation="MPKLKEELRTIFNDYGLKYVFDTNSQEIKVMKEKKPGEIFLIPF
                     HSIADTLQRMIFYKAAIESNSESALVFEEPEAHSYPPFISKVTQDIIQSDRNQFFITT
                     HSPYVVNDFLELPSDELAIYLVDFKNGETFVKRAIDTEVQEMYEYGIDLFFNTET"
     gene            complement(48154..48657)
                     /locus_tag="ACZPB4_00680"
     CDS             complement(48154..48657)
                     /locus_tag="ACZPB4_00680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3868 domain-containing protein"
                     /protein_id="HIR1096776.1"
                     /translation="MKTFIYICLLVIGLVLPAGAQVPIQSYRGQVSVKQNRIEREGNS
                     LRLDLTISVCGLSVGRYQTLSLMPMLRSDRDSVVMAPVVLNGANKQKMYDRTLVFEGK
                     KAADGDTYTVIKNTPELIREIPYELSIPYHPWMNAALILVGELDNYEGAPLRTFVNVL
                     TEHLDIP"
     gene            complement(48670..49230)
                     /locus_tag="ACZPB4_00685"
     CDS             complement(48670..49230)
                     /locus_tag="ACZPB4_00685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3575 domain-containing protein"
                     /protein_id="HIR1096777.1"
                     /translation="MNKLYLLLVFLLSTFMDIQGQVVAVKTNVLYDAITTPNVGAEVA
                     FNKHWSVEASGYYNGWTFSSDKSFKHWMIQPEARYWIHERFNGHFFGVHAQYMDYDFA
                     GLKLLYGMEKKNSYNGNAYGGGISYGYQLYVSPRWNVEFTAGFGYLHFEYDKYAFPRG
                     DAPIGKFRNEYWGLTKAGISIVYIIK"
     gene            49382..50515
                     /locus_tag="ACZPB4_00690"
     CDS             49382..50515
                     /locus_tag="ACZPB4_00690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="clostripain-related cysteine peptidase"
                     /protein_id="HIR1096778.1"
                     /translation="MKAKYIVIFFLSLLSFVACDKEEVVIPTTAPRTVLIYFAGDNSL
                     SGYVSQNLRAIKEGIERDGLNNGNLLIYTDKQNEAPQLFQLKLEADTIRQIVLETYDS
                     NQNSASTETLTQIIDKVQKEYPADSYGLVLWSHGTGWLPSDIYSYLRSFGQDGKNNFM
                     EINDLASALSKYHFDFILFDACYMSCAEVAYAFRGCADYIIGSPTEILANGFPYQSIM
                     GDMFKKEADVVGIATKFYTYYQSEAGTISVMKSDELDELAATCRTLFHDKTESDLFAV
                     PVSELQIMEYLTPNYHALYDFDDYVSRLATEEQYNAFKRSMEKAVIYKATTPKAVYAY
                     PYPYGSYLPVNKYSGLSIYVPQEALPKLNEWYKDLEWYKDVYQ"
     gene            complement(50627..50893)
                     /locus_tag="ACZPB4_00695"
     CDS             complement(50627..50893)
                     /locus_tag="ACZPB4_00695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1096779.1"
                     /translation="MSNYNGNIEKRKAAQDLMKNRRENTSKYFFDLSKLTFAALVLGV
                     GSALLNRWEDTRDIMLWPPIFWYSLFTGTFIATVFALIGYKLLK"
     gene            complement(50927..53308)
                     /locus_tag="ACZPB4_00700"
     CDS             complement(50927..53308)
                     /locus_tag="ACZPB4_00700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005882 - intermediate filament [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lamin tail domain-containing protein"
                     /protein_id="HIR1096780.1"
                     /translation="MKQLLLILAFLLPLCAYPQLKEPFNGPEITSDNPWTGDLDCFVI
                     ENGWLVSRADPTRKSVSIETPLVYSATMEWEFEIRMDFKPSDQNHIRLHVYLDDQRML
                     GLKNDYYVQIGSNKKTITFRKHTATEKNPKILIEKALDVLLGAVDLKVKLTLENHKIW
                     NLYVLEKGRFVLIGSCESEVSSSCKGGQLRFECRYSKTRVNDFACNYIIISDNISIEP
                     EKPDTPEEPEEPNEPDEPDEPLVLPRLLAIQPITESVFQLQYNLPVDIREAIFSISGI
                     GNASRMTYADDMRIHVNISFDKELKVGMGYDLLCSGLMDLEGNKIPESSTEIRLEYEE
                     EPDVPEEPEVPDTPSFPAGSIRINEVMADPKGQKAFPETEYVELYNTTDKAIELNGWS
                     FLYGSKPTVLTALLLDADGYVVLYRSGRDIHIDDAGLDLPLDKFPASLANTGKELALL
                     DPSGKEIDRIAYEKAKAGIAWERSETGFYLSTDERGGTPGSANSSPDDEPEDPDRPDT
                     PHKPGIPTDIIVLPNEIIFNELLSNPYPEGSEYIELYNRSDRTLPLAGLSVATRKSDG
                     TLSTHYPLSSIVSPVEPQDYALLTKSIEGVSDFYLISSPDALHELKLPVLANTSATLV
                     LFRTEDEVMIDEIRYSSKWHAPSVKNEKGIALERINPDSDTQDEMNWTSASATAGYGT
                     PGYRNSQYGKQDEGEVTGIESPVYSEATKEYTISYHLDESGYTCRAWIFDISGRRISE
                     VVNHDLLGIEGELAWNGLAVNGSKVRTGVYIFYAELVHPQGQVKRYKEVFLVK"
     gene            53463..54473
                     /locus_tag="ACZPB4_00705"
     CDS             53463..54473
                     /locus_tag="ACZPB4_00705"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005843608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HIR1096781.1"
                     /translation="MKVAIVGVSGAVGQEFLRVLDQRNFPMDELVLFGSSRSAGRVYT
                     FRGKQYTVKELKHNDDFKGIDVAFVSAGGGTSKEFEKTITKHGTVMIDNSSAFRMDED
                     VPLVVPEVNPEDALNRPRGVIANPNCTTIQMVVALKAIENLSHIKRVHVSTYQAASGA
                     GATAMAELVKQYEQLLKGEEPTVEKFAYQLAYNVIPHVDVFTENGYTKEEMKMYNETR
                     KIMHSDIEVSATCVRVPVMRAHSESTWVETERPISVEEARKAFAEAEGVVLQDEPANK
                     DYPMPLFVADHDPVYVGRIRKDISNPNGLTFWTVSDQIKKGAALNAVQIAEYLLKVGN
                     IK"
     gene            complement(54569..55789)
                     /locus_tag="ACZPB4_00710"
     CDS             complement(54569..55789)
                     /locus_tag="ACZPB4_00710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005779570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DcaP family trimeric outer membrane transporter"
                     /protein_id="HIR1096782.1"
                     /translation="MKRNLLLLIGLCMAVCVQAQKKNFSYKFYGQVRGDLFYNSRANA
                     EIVDGLFHLYPKDVALDADGKDLNASPNGSFYLLYSRLGIDVQGPKVGSAKTSLKLEA
                     DFRGSGSNWAVLRIRHAYVNLDWGKSAVLIGQTWHPLFGEVFPQMLNLSTGAPFQPFN
                     RSPQIRYRYTDNGWQLTGSVLWQLQYLSAGPNGKSEEYIKNSCVPEVYLGVDYKKPGW
                     QVGAGMEILSLVPRTQNEVDGKIYKVSERVTSVSGEAHVKYQDANWLVMAKTLLASNL
                     TQTCMLGGYGVTSIDSRTGEQEYSPYLFSTSWLNIVYGKKWKPGLFLGYLKNLGANEA
                     LVGKTYGVGLDVDQVFTTNLQLSYNLPHWKLGVEYSPSIAWYGNVDLQDGGRIHDTHS
                     ITNHRVLGVLIYTF"
     gene            complement(55812..57041)
                     /locus_tag="ACZPB4_00715"
     CDS             complement(55812..57041)
                     /locus_tag="ACZPB4_00715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DcaP family trimeric outer membrane transporter"
                     /protein_id="HIR1096783.1"
                     /translation="MRRITLLLVGMLALFSTTAQRKNFTYKFYGFVRGDLFYNSRANM
                     APIDGNFYLYPLDKSFDADGKDLNATPNGSFYTFTSRLGLDVTGPDIGKARSSAKIET
                     DFGGFSGSNTMLRIRQAYVNLDWGKSAVLVGITWHPLFGAVMPDVLNLSTGAPFQPFN
                     RSPQIRYQYKANSRVQLTASVLWQLQYLSSGPKGMSEDYIKNSCIPEMFVGADFIPAD
                     GWLMGLGAHMISLKPRTSTEWKEQTFKVNERMTAFSYEAHLKYSGRNYTFAAKTLMAS
                     ALDHTALLGGYGVSSVDSRTGEQGYTPFRHSTTWVNFAYGTKWRPGVFVGYTKNLGTG
                     KSLVSADKVYGMGLDIDQLITVSLNVSYNLPHWKFGFEYCPATAYYGTTDLESGRIEQ
                     THAITNHRILGLMMYYF"
     gene            57201..58562
                     /locus_tag="ACZPB4_00720"
     CDS             57201..58562
                     /locus_tag="ACZPB4_00720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0000162 - L-tryptophan biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0006568 - L-tryptophan metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrpB-like pyridoxal phosphate-dependent enzyme"
                     /protein_id="HIR1096784.1"
                     /translation="MSTKKFLLEEKDIPTAWYNIVADMKNKPLPILNPQTKQPLKEED
                     LYPLFSKGVSHQEMNTTDTWIEIPDEVRELYKVWRPTPLVRATGLEKALDTPAHIYFK
                     NESVSPIGSHKLNSALAQAYYCKQEGTTNITTETGAGQWGAALSYAAKAFGLELAVYM
                     VKVSYHQKPYRRSIMQTFGAQVVASPSMSTKAGRKILTDHPNYQGSLGTAISEAVELA
                     MQTPNCKYTLGSVLNHVMLHQTVIGLEAEKQMEMAGEYPDVVIGCFGGGSNFSGITFP
                     FLRHKLTEGKDIRVIAAEPASCPKLTRGQFQYDFGDEAGYTPLIPMFTLGHNFSPANI
                     HAGGLRYHGAGSIVSQLMKDELMSAVDIKQLDTFKAATLFAQAEGIIPAPESSHAIAA
                     AIHEAEQAKIEGKPRTILFNLSGHGLIDMAAYDQYLSGDLTNYEVTDEEVANNLKDLE
                     KII"
     gene            complement(58640..59050)
                     /locus_tag="ACZPB4_00725"
     CDS             complement(58640..59050)
                     /locus_tag="ACZPB4_00725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3836 domain-containing protein"
                     /protein_id="HIR1096785.1"
                     /translation="MKTSVWGKSILALVFTFMCSLAISAASPKDYLYDTKEENGKIIS
                     KVVFLQENGLLNKQVRYEFQYNENGKVSEKKAFRWDRTNDEWVPFYQITYQYDDQSGE
                     IKTNYGMWDKKKKNFSLNVQNMIIPSTNYEEIFS"
     gene            59383..60582
                     /locus_tag="ACZPB4_00730"
     CDS             59383..60582
                     /locus_tag="ACZPB4_00730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LruC domain-containing protein"
                     /protein_id="HIR1096786.1"
                     /translation="MRQIMKLFITSFLFILFSGCTKDVYDPSDKIPGEGTNPFSKVTI
                     SSNFDWSMIQISHLTVQSFDPYDGTYNYLVEVFDKSPEDQDANLLATGVCSKKTLFDK
                     KIIYPKGESDQVYIKLTTPTGYQVTAPVTLTPGNDNVCAFDSLAVSQETTATPVSRTP
                     TRSVSSTYTFIIEDSFPNYGDYDFNDAVIKVQMETSMKDDYVQFANIKLTFRPLGGTK
                     RAGAFIHLPGIKSKDIQKAELNGWTTTPESETETPVYALSDDIHGLFSFHEMINTDND
                     LPYRGKQERLITFSFAAGALKDLTIDDIDLFTTVLKREGEVLRTEIHQRNYSYTPKGV
                     RYRYYSNDNCIWALMIPDDFKYPVEHAFIGDAYPDLLKWVSGDSKHVQWYKSKNTVDK
                     WIYTREQ"
     gene            60604..61752
                     /locus_tag="ACZPB4_00735"
     CDS             60604..61752
                     /locus_tag="ACZPB4_00735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BPL-N domain-containing protein"
                     /protein_id="HIR1096787.1"
                     /translation="MKTTAILFLAFLALCVQCSVPENKSTKKEISTQPIKVGVFDGHG
                     GAQTCIWETVAAIRLDPEMEVRTITTADIANNALDSIDAIIIPGGSGKSQYLNLGTLN
                     QQRIKDFIAKGKGAVGICAGAYLFSNTPDYTCIQLNGQQAIDIEHDNRGHGLAKFTLC
                     EEGKKIFPELADRDTSFVIYYEGPVFINNPADTIQSNTLAIMESDVHEEGNAPANMTN
                     GKPFFVANNYGKGRVFSSIAHPEGTPGMMWMIPRMVRWTLNKPFIPYQSSAVRPDLFN
                     HESLMATDDLKQEEKAFQILLSGESEQKVAALDWLEAHHSWDAKRWVQGLLYDASPAV
                     RIRAARYIADTHYLPFLPNLQAAYRTETDKATQEELKTQLEKLTALLP"
     gene            complement(61764..62435)
                     /locus_tag="ACZPB4_00740"
     CDS             complement(61764..62435)
                     /locus_tag="ACZPB4_00740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2461 domain-containing protein"
                     /protein_id="HIR1096788.1"
                     /translation="MNEQIIEFLTELRSHNNREWFQDNKNRYDALRKVFIDEVQDLIG
                     RISLFDPEVAGLEAKDCLFRIYRDIRFSPDKTPYKCHFAAYISQGGRASERGGYYIHL
                     EPGGCLLSGGVWCPPPALLKKLRQDIYDHIEEFTAIIEEPTFKKTFPVLEGEMLKRMP
                     AGYPMDSPYGYIMKHKDFSVVSYKPDNFFYATDWMDKAVDDFKLLLPFNRFLNYTVDE
                     YLGRV"
     gene            complement(62473..64677)
                     /locus_tag="ACZPB4_00745"
     CDS             complement(62473..64677)
                     /locus_tag="ACZPB4_00745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HIR1096789.1"
                     /translation="MRKFLLLWLVGLMLVPSVMAERKKVGLVLGGGGAKGVAHIGVLK
                     VLEEAGIPIDYIAGTSMGAIVGGLYSVGYNAAEIDSMVRLQDWSMLLSDRVKRSSLTF
                     PEKENSERYVFSLPFGRSKKEIAIQGMIKGQNLQNLFSNLTIGYHDSVDFNQLNIPFA
                     CVALNVVDGQEYVFHHGSLPLAMRASMAIPAVFAPVRLDSMVLVDGGIKNNYPADVAR
                     DMGADIIIGVDLGTSDLKQLERINTPWDIVGQIVALHGYEKYGPNKEQTDLLFRPNTD
                     PYNSASFGETALDTLIDRGEQVARKQWDEILALKKKIGLSDSSDMHRKRLVHSYPVAP
                     TDTFHIRRVLFEGIDPRDEKWLTQISGLKENSLLTVKKLQEAMSIVIGTNLYSNVSYK
                     LVGERQEDLVLTVQEKSNSAINVGLNFNSEDIVALLLNVTFDNRARYHSKFSVTGRIG
                     KRMYGRVDYAIERNPLRNINLSYMFTYHDLDVYNRGNKIVNTTYRHHFVELGYSDMNW
                     LNFKLKLGARYEYFDYNSFLYTAENQKYQVKPEGFISYFAQAHLETLDRRYFPSKGVS
                     LQADYSIYTDNFVTYKGHTFFSALKLSFLSVLPLTSHLSLLPSIDGRVLIGKDPAYPF
                     LNVVGGDMPERYLPQQLPFAGINHMEIFDNSVAIVRLNLRQRIGQRHYISLIANYAIH
                     ENNFFDLFKGESVWGGSIGYAYNSIVGPMNTNFGLSNRNNNLQFYLNLGYSF"
     gene            complement(65123..66280)
                     /locus_tag="ACZPB4_00750"
     CDS             complement(65123..66280)
                     /locus_tag="ACZPB4_00750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-bladed beta-propeller"
                     /protein_id="HIR1096790.1"
                     /translation="MRKLTTNAVAMLLALVGCMGCGNRSASSVDNLIRVDVMADYPEK
                     ELILQDLMDVEYIALETTDDFITKGAVKAIGKDIMLVTNRGSDGDILVFDKNGKGLRK
                     INRLGQSGEEYTQLTGLVLDEDNDEIFVKDNPARKIGVYDLLGNYKRSFKFTDTSYYN
                     YIFNYDRDHLICYKSYPSEKGKRECHLIISKQDGRITHEIQIPSKGIETPVVTEGEFV
                     ITPEFYLTFPDRDKWILVNTSSDTIFHYLPDGNLSPFIVRSPSISSMDTKVFLFPTVI
                     TDRYCFMRTMRKEVDFTTFKGFLGEDLVYDKQENALFSYILYNDDFINKEEVSLTSEP
                     RNPEIAICQTLDAPDLVEAYEKGQLKGKLKEIAANLDEESNPVVMLLKKKK"
     gene            complement(66312..68174)
                     /locus_tag="ACZPB4_00755"
     CDS             complement(66312..68174)
                     /locus_tag="ACZPB4_00755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HIR1096791.1"
                     /translation="MNEKCNLVTVLLLCCLIFPGNAQEFNWQDLVNRKQYAAVIAHAD
                     SLTLADSSNYEIMNAIGQAYEGMLRYQKAYDYYRLCFSMDTTNLDILNILARTATNLG
                     RAEDAERYFHQVLSADSSNFYANYQLARLYFQLGEYEKAVDAYEKLQAQNEDNTVLYR
                     AIGDCYTRMEQYPSATTAYFQAYNLNRENAGLAVALVNSLYRMGASSPDYISEGIAIC
                     DTALFYNPGNRQLLRSKGLGLYIVKQFVQADSVYSSLLADGDSTYLTLKYGGASKYYA
                     GLYMPSVDILDMAYEQDTTSVEVCLLLGSALGKTYDRKRAYDLFDRAEKGLEPNRFLV
                     NQLLAFRAETYQKDGRYKEASRLYYEAWKKNPERLDFLAAISHMYSEIDVSKFQSEED
                     RQRGLFILVLYMNESLKKKADERMMVFSRALLQSFYEDMFFRNVAEETMIDPDGKKSK
                     ISIVDLRNLINQLPEESEMVMEIRAMSARSSGKIEEAARLLYRAWKVKGTRVELLREI
                     ANLYSHPDISGFKNAEELQRGVFAQVTYAKELLKNESDLSNLTFTRPFLESLNSDMSK
                     RGITEQTMLAPDNRKSQLSIDELQSLIQQLPETSDEVKEMIRMMNKEKALKSKK"
     gene            complement(68231..70054)
                     /locus_tag="ACZPB4_00760"
     CDS             complement(68231..70054)
                     /locus_tag="ACZPB4_00760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015291 - secondary active transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB family protein"
                     /protein_id="HIR1096792.1"
                     /translation="MTPEFAYLLKVNVAFVLFYAFYRLFFYKDTFFKLRRAILLAFFG
                     LALFYPLLNIQDWVRQQEPIADVIYMYSAMLPEATAKADAAASVDWYGWLLGSLGFIY
                     WGIVAFLCGRFLVQLSSILWLAHTSERVVIHETPVYALRKAAGPFSFFRMVFLHPESH
                     SDKETDEILTHECTHVSQWHSIDVILSEMMCMACWFNPFVWLLKREVRHNLEYLADNT
                     VIQSGYDSKSYQYHLLGLAHHQSVTTLYNSFNVLHLKNRIMMMNKKRSPGIVRTKYLI
                     FIPLVGILMLLSNIEAVARLTVRLANETTVSNAMVTATGILVDETGKPLIGASVVVKG
                     GKEGTITDRKGAFSLEVPANAILRCSYQGRESQEVLAADMTNNTHLSLSSKSREMNEQ
                     VFTVVEKMPSFPGGDAELLKYIATNIKYPKESQDNGEQGRVICSFIVGRDGSVNNPEV
                     LRGVTPLLNEEAVRVINTMPRWNPGMQRGKAVAVKYTVPITFRLKSPVEETKEETLTV
                     VDVMPQYPGGDRELLKFIAQSIKYPTDAQEAGVQGRVICSFVVDKKGNIVEPKIIRGI
                     DPSLDAEALRVIGMMPRWTPGRQDGKAVRVLYTVPITFRLQ"
     gene            complement(70072..70434)
                     /locus_tag="ACZPB4_00765"
     CDS             complement(70072..70434)
                     /locus_tag="ACZPB4_00765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HIR1096793.1"
                     /translation="MEKLTMQEEEAMRWIWRIGPCFVKDVLAKYEDPKPPYTTLASVI
                     KNLERKKYVKAKRYGNTYEYRPLIEETEYKRTFLGGVVTNYFANSYKEMVSFFAKDQK
                     ISTDDLKDIIDLIEKGKE"
     gene            complement(70550..>71049)
                     /locus_tag="ACZPB4_00770"
     CDS             complement(70550..>71049)
                     /locus_tag="ACZPB4_00770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_function: GO:0031992 - energy transducer activity
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="energy transducer TonB"
                     /protein_id="HIR1096794.1"
                     /translation="LKMKKAIMNTMIILFALAMCVGCGQSSEQKEESVPTDVTKAEKQ
                     EQVQVEAEDEDTLENGEQVFRVVEVMPKFPGGDAELLKFIAKNVKYPQESQDKGEQGR
                     VICSFVVTKDGTLTNYKVLRGISPALDQEAVRVLQMMPRWTPGTQRGEPVAVKYTVPI
                     TFKLQ"
     assembly_gap    71050..71149
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<71150..72044)
                     /locus_tag="ACZPB4_00775"
     CDS             complement(<71150..72044)
                     /locus_tag="ACZPB4_00775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-bladed beta-propeller"
                     /protein_id="HIR1096795.1"
                     /translation="MKSVKLASILFYLNSVFVVSCFVSCGSSPTEASSLLTADIRGGM
                     DKPGLLELGDEIKGVTFVPLEVTTDDASLIDGVYDYAVTDRYIYVLPVKEPRIVLFDR
                     QGRFIRTLVKEGQGPGEFSGILPCIQVDERNDRLFLFSNNRVWEYTLEGEFIGQSTHE
                     YSVIYMRHIGKDRFAAISFPFQPFNGGGFGLGLFSGKGDTIAIKNDFYSFLLPHEKSG
                     FTTSIAPAYSDAQNSVLFKTGSNDTVFCISADRISAACVLDLKNSDAEVIRSLDVTDM
                     SNLRIEKKDPKDIFVQDMIEFP"
     gene            complement(72154..73569)
                     /locus_tag="ACZPB4_00780"
     CDS             complement(72154..73569)
                     /locus_tag="ACZPB4_00780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HIR1096796.1"
                     /translation="MNNLYTFAYMRKDLNGSRHFSIGIKFTILLFTIVILVLVLFSYR
                     SDKHGNLFWQVEKLIPHHPDSALVLLEKVRDINGLSLREKARYCLLWTESRDEAGLRH
                     TSDSIISIATDYYRTTRGCYWPPKAWFYRGKVYEDMDQPSLALECYLRALEYEGENWD
                     YEFWGRLYNQMGMLYAEQELYGKAMSFLRKASAQYQLLNDAAGQDRILTEVKKYEMLR
                     DSIGSLSARESIYQITSRYDVRPIREDLSKKELMLLQRGQERYLYAFIIGIILFICFL
                     LYRRWRNTQENALRREEALRRSIASQQQRMREEKEENERQITLLEKRITKIKEEKDQE
                     LMLVSLQLEKQRLEICNESILNKESKHLLSVAILRKSEVYEKFHDRDAGKIISEDWEL
                     LEVLLNKAYDDFTLRLKKLYPVISDTELKACMLTKIGVPANQITRVLKYNSSVLRPRL
                     FRKIFKKEGSTEAFVEFISNF"
     gene            73755..74447
                     /locus_tag="ACZPB4_00785"
     CDS             73755..74447
                     /locus_tag="ACZPB4_00785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase cytochrome b subunit"
                     /protein_id="HIR1096797.1"
                     /translation="MWLLNSSIGKKLIMSISGLFLVLFLLFHLSMNVAAVFSGEAYNM
                     VCSLLGSNWYAVAATLVLAAGVVIHFVYAIILTLQNRKARGNDRYAINARPKGVEWAS
                     QNMFVLGLIVILFMLLHFSQFWYKMMFAELIGHHEVALGSAMVSPQDGAAFINYYFQG
                     NAVITVLYLIWYVALWFHLTHGFWSAIQTIGWNNTIWMNRWECISKIVATVICGLFAI
                     ITIIFFLNGVGA"
     gene            74496..76439
                     /locus_tag="ACZPB4_00790"
     CDS             74496..76439
                     /locus_tag="ACZPB4_00790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005633282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase/succinate dehydrogenase
                     flavoprotein subunit"
                     /protein_id="HIR1096798.1"
                     /translation="MSEINSKIPQGPLAEKWTNYKNHQKLVNPANKRRLDVIVVGTGL
                     AGASAAASLAEMGFNVLNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTI
                     KGGDYRAREANVYRLAEVSNSIIDQCVAQGVPFAREYGGLLDNRSFGGAQVSRTFYAR
                     GQTGQQLLLGAYSALSRQIGLGKVKMYTRHEMLDVVKVDGRARGIIARNLITGKIERY
                     AAHAVVVATGGYVNTFFLSTNAMASNGSAAWQCYKKGAYFANPCMVQIHPTCVPVKGD
                     FQSKLTLMSESLRNDGRIWVPKKLEDAKALQAGTKKGKDIPEADRDYYLERRYPAFGN
                     LVPRDVASRAAKERCDAGFGVNSTGLAVFLDFSDAINRLGKEVVKQKYGNLFDMYEEI
                     TNDNPYETPMMIYPALHYSMGGLWVDYELMTSIPGLFAIGEANFSDHGANRLGASALM
                     QGLADGYFVLPYTIQNYLSDQIQVPRFSTDLPEFVEAEKAIKDRIQKLMNVKGKETVD
                     TIHRKLGHIMWEHIGMARDAKGLQEAIQMLKDLKKEFWSNVFIPGNADNLNTELEKAL
                     RVADFIEIGTLMAHDALDRAESCGGHFRTEHQTEEGEALRHDDKFMYVSCWEYQGEDK
                     DPVMLKEDLNYEFVVPQTRNYKK"
     gene            76470..77225
                     /locus_tag="ACZPB4_00795"
     CDS             76470..77225
                     /locus_tag="ACZPB4_00795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase/fumarate reductase
                     iron-sulfur subunit"
                     /protein_id="HIR1096799.1"
                     /translation="MDKDISVTLKVWRQRGPKEKGQFETYKIEKINQSVSFLEMLDIL
                     NEQLVNEGKEPIVFDHDCREGICGMCSLYVNGHPHGPATGATTCQLYMRRFHDGETIT
                     IEPWRSAGFPVIRDLMVDRYAYDKIIQAGGFTSVNTGGVPDANAIPIPKKDADLAMDA
                     AACIGCGACAAACKNGSAMLFVSAKVSQLALLPQGKVEAARRAKAMVAKMDELGFGNC
                     TNTRACEMECPKNISVSNIARLNREFICAKLQD"
     gene            77648..78859
                     /locus_tag="ACZPB4_00800"
     CDS             77648..78859
                     /locus_tag="ACZPB4_00800"
                     /EC_number="1.17.98.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HIR1096800.1"
                     /translation="MDKKRTTSSFRAMSTERKLESIFLFVTGRCNAKCAMCFYAQEMD
                     KKQPDLTFDEIKKISETAGQFNRLWISGGEPTLREDLPEILELFYKNNHIKDVNIPTN
                     GLKPDRIVEWVKRFRQNCPDCNINVSLSLDGFGTTHDTQRGVPGNFYKALETLRKIQE
                     NFGDDGKVLKNIATVITKYNIDQIEDFMTWVYGRFRTSTHTIEAARGMTRDDGVKILT
                     ESTLRKIQDDISPIYSAYADRMVADTTGLRKPITRFFYLGLIRTLYNVRASNIDHPTP
                     WGMDCTAGETTLVIDYDGRFRACELREPLGNIKEYGCDISKVMNSEAMKQEIAAIGHG
                     YKANCWCTHGCWITSSVIFNPRKMIRSVYKGYRETKRLNHPLAINEQKLQTMEAKYHL
                     DIERLRQLNIR"
     gene            78893..80125
                     /locus_tag="ACZPB4_00805"
     CDS             78893..80125
                     /locus_tag="ACZPB4_00805"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009101 - glycoprotein biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HIR1096801.1"
                     /translation="MKILLVTRGSQGDVLPYLAIAAELERRGHEVTINLPQIFEETVK
                     PYGFKYVLQQFDDIGGMIDSAAQNSHKFRPFLKWMRNVIDKQFDQLIPLLKEHDILVS
                     TNSEFAVASIAEYCKKPLIRTAYAPFLPGKKIPPAVLPFPKPNPIITPAILWKLMNRM
                     TNFMVKDTINKNRAKYGLAPIRNFGYHAGERSYNYLLFSQHLGNIDPDWTFKWSIGGY
                     CFNDTFQYDEKAYEEMISFVDSAQSPIIFFTLGSCSSKDGNRFSKALVDICKKHDYRL
                     IIDSGWAKTGITLQADKHLFLMKQPVPHNLIFPHCDGVIHHGGCGTTHSVGRAGKPQL
                     ITPLIIDQPYWSYRIHQLGLGPEGLKIAKASEQEIERKVCDLVTNPLYKKNAAHIGEM
                     IQKEGGIKNICDSIERFQ"
     gene            complement(80331..83468)
                     /locus_tag="ACZPB4_00810"
     CDS             complement(80331..83468)
                     /locus_tag="ACZPB4_00810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HIR1096802.1"
                     /translation="MIRNIINLKAIILYFGLILCLIAGMPTPAYGSSSYPVKEESYVL
                     VINSYVDGERWSGNLLNMISKFATPEEYTLRIDHISVMLVDTPEKLKEKQEVFFEANK
                     KKPDGIIYLGVNGWAFMRDKIREKWGDIPTLVCSETGEMAENECYFNQRHSSDRVIPL
                     QEAVKGYNATGLVIPYYVKGSIDLVKELIPGLKRLIFISDRRYVSTWLRDEMEKHMET
                     SFPEGKVDFYTEGSCSMDSLLAVLSEKDPHRATAVMYYSWITEKPFLNHSLLYSTLYQ
                     GINGISRHPVFSLYDMGVEEGYTIGGYYNSAKTIETALIPLLQQVYNGEDMGKIPVST
                     VNDPHKYLNYASLISAISNEDNFPRDAIYLNAPPSFLEKYWMQLLGFLIFFLVVVFLA
                     WHYVYRSKQKMKEVELRLLSRYRDLFNNMPLPYIRQRLIREGTQIDVQVLDVNHAFEE
                     KIAPKDFVVNKRGKEIANLIGGSYPLLLSAVPTVLESGKSFTYEYYFEPTGLYYTIII
                     MPTSEENVVDAFFIDITDIHKFQTHLKAMNHKLAMALEAADLLPWRYNLAEEKIIYES
                     KVHPGDNIETAEVHTHEVSLKEYFSKIHPSFRACVEKAFDDLCNGKIKKVRKEYCLER
                     LIPGEDRHEWEEIQVMVEYDASGKPKALIGSTISITERKQLEHDLRMARDKAEESNKL
                     KSAFLANMSHEIRTPLNAIVGFSNILASTDNLEDKKEFADIIENNNSLLLQLINDILD
                     LSKIEAGTLEFTYDYVDINAVLRDLEQSAHLKNKNPDVQISFKDYLEPCVIYTDRNRL
                     SQLMINLLNNAMKFTQAGLISFGYKLRDDNTLWFYVEDTGCGIPENKRKDIFGRFVKL
                     NTFAQGTGLGLSICEMIVTQMKGTIGVDSMEGKGSKFWFTLPFQPKKELFPSEEQKPV
                     TLEKIARSEVTILIAEDNSSNYRLFESILKPEYKLIHAWNGKEAVELFYQHKPQLILM
                     DIKMPVMDGYEATAEIRKVSASVPIIAVTAYAFAQDEQRIINSGFDAYTAKPINGKIL
                     KDKISTLLTHRIILM"
     gene            83707..84474
                     /locus_tag="ACZPB4_00815"
     CDS             83707..84474
                     /locus_tag="ACZPB4_00815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LiaF transmembrane domain-containing protein"
                     /protein_id="HIR1096803.1"
                     /translation="MDMKDYDIDFKEKRTNGYLIATLFIIVGILFLLRNLGMIDPSLF
                     DLLVSWPMLLVVSGIFMIFHRNPVGGMLLVGVGVYFLFPQLNWITNDFLRIYWPLGLI
                     LLGLVIMLKRKDSIRTKKHKRPFNHPPFGHRKPNDEINYETDNGFVAVDTTFNSVRHI
                     VLDPVFKGADIDVSFGNVILDLKKTTLEADETIINIDSSFSGVVIYVPKGWLVRLKVD
                     SFLAGCQDMRDLTETTDMTHTLYICGDLSFSGLELRD"
     gene            84482..85276
                     /locus_tag="ACZPB4_00820"
     CDS             84482..85276
                     /locus_tag="ACZPB4_00820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HIR1096804.1"
                     /translation="MQEHPITTSILHKGLGSLLLLLAIAIQCALLTLYGDLPLSITLV
                     DSLLSIALFAVAGYYLWYVQCTLHIMQARVAFAVLVQIACIAGCSILLQIFGLEDWEE
                     FSITIPFRFLFGLMAWIILSQWYASRERKSEAEPIVRQMEEKTAPPPTTVPEEILDRI
                     SVKDGTRIHIIPIKEIFYLQACGDYVTLFTTSGQHVKEQTMKYFERSLPSPEFVRIHR
                     SYIVNTEQILRVELFGKETYQVRLKDGTYLRASSAGYKLLKERLSL"
     gene            complement(85614..86132)
                     /locus_tag="ACZPB4_00825"
     CDS             complement(85614..86132)
                     /locus_tag="ACZPB4_00825"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HIR1096805.1"
                     /translation="MKKYWHIALMLFCVLMITSCGDDDEALEVDEVWKVQNEEAFQAQ
                     MLVPGFEQLSSQSNAGFILYKVLKTGESKEPIYYTSKVECYYKGTFIDGTVFDDKSFE
                     AGAPAELTVSEMVDGFATALQNMHPGDRWEIWIPQQMGYGSAGRSASGSVIIKPYTTL
                     IFDLEVTRIVKE"
     gene            complement(86137..87681)
                     /locus_tag="ACZPB4_00830"
     CDS             complement(86137..87681)
                     /locus_tag="ACZPB4_00830"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase"
                     /protein_id="HIR1096806.1"
                     /translation="MAQEDVFKKLVSHCKEYGFVFPSSEIYDGLGAVYDYGQYGVELK
                     NNIKKYWWDSMTLLHENVVGIDSAIFMHPTIWKASGHVDAFNDPLIDNKDSKKRYRAD
                     VLIEDHLGKIEEKINKEVAKAAKKFGDAFDEAKFRETNPRVLEHQAKWNEIHERYSKA
                     MNESNFEDLRQLILDCEIVCPISGTRNWTEVRQFNLMFSTDMGSTADGATKIYLRPET
                     AQGIFVNFLNVQKTGRMKIPFGIAQIGKAFRNEIVARQFIFRMREFEQMEMQFFVRPG
                     EEIEWFKKWKSTRLKWHQALGLGDQKYRYHDHEKLAHYANAATDIEFEMPFGFKEVEG
                     IHSRTNFDLSQHEKFSGKKIQYFDPELNQSYTPYVIETSIGVDRVFLSIMAGSYCEET
                     LANGESRVVLKLPAALAPIKLAVLPLVKKDGLPEKAEEIINMLRFDFRCQYDEKDSIG
                     KRYRRQDAIGTPYCITVDHDTLKDNCVTIRFRDTMEQERVSIDKLHDIITEKVSMKNL
                     LKKVIE"
     gene            87889..89325
                     /locus_tag="ACZPB4_00835"
     CDS             87889..89325
                     /locus_tag="ACZPB4_00835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HIR1096807.1"
                     /translation="MKSEEISRRSFLKRALALSAVSAIPSFWTPAHGRVLPTSPLISA
                     NDRVNIAFIGIGQRGGEIAKELYNTGLCNVVALCDVDMGAPHTQEIINMFPKAARFQD
                     FRTMFDRMADKIDAVSVGVPDHSHFPITIEAMAHGKHVYVEKPMARTFQEIEIMMRGA
                     KKYGVVTQMGNQGHSEANYFQFKAWKEAGIIKDVTAITAHMNNPRRWHGWNPNIRHMP
                     MGEPVPETMDWDTWIGVAQYHDYNHDYHLGQWRCWYDFGMGVLGDWGAHILDTAHEFL
                     DLGLPTEINPLYLKDHNPFFFPMSSTLLFKFPERGNMPAVDITWYDGLDNIPSVPEGY
                     GVSELDPNIPTVAGGKIQPAKLNPGKEIYSKELTFKGGSHGSTLSIIPDEKAKEMESR
                     LPEVPKSPSNHFANFLLSCMGKEKTRSPFSIAGPLSQVFCLGVLSQRLNRKLVFDRDT
                     KQITNDPEANKMLCGVPPRKGWEQYYTI"
     gene            complement(90022..90462)
                     /locus_tag="ACZPB4_00840"
     CDS             complement(90022..90462)
                     /locus_tag="ACZPB4_00840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1096808.1"
                     /translation="MSTLHYKYDEQGRKIKGITEYPVIGKSKVTVFSYKNNLLERKVE
                     YDKLGRKLTYTDYEYDETGLLTKETIRDPETSEVLRYSEYRNENGLNMEIMVYADLPT
                     EKESIELRRITKSYDQNGNLLQLVSEELASSSSQSSFSESYEYI"
     gene            complement(90561..91328)
                     /locus_tag="ACZPB4_00845"
     CDS             complement(90561..91328)
                     /locus_tag="ACZPB4_00845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0015288 - porin activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="porin family protein"
                     /protein_id="HIR1096809.1"
                     /translation="MKKLILFVLCALSGLMVSAQSRWGITPEGGFAAVNRVGMGSSWR
                     AGVKVGVGVSYQFEPGWIGLKSGLYYANRGYSLGDYPRTTESATYVLKEMMTGGITQH
                     FLQLPVMADFSWKVSKEVRMHLAVGMYAGVSVKNDTNWGSSFTMGYSKEPQALGKYVK
                     STGLGYSYGYGHSGYDEAENADHPFRDVNSFDWGLTTSFGIEVNNWVMNLGYDLSLGD
                     EGGNYKIDGDNFSLYEVRSVGANYNTMSLTVGYKFKL"
     gene            91547..94282
                     /locus_tag="ACZPB4_00850"
     CDS             91547..94282
                     /locus_tag="ACZPB4_00850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase/topoisomerase IV subunit A"
                     /protein_id="HIR1096810.1"
                     /translation="MRPEDKEDDYIEDKENEEIEDINSDTQDNETTEEEANTHSDYKV
                     PGKGDTRVTTYHLSGMYQNWFLDYASYVILERAVPHINDGLKPVQRRILHSMRRLDDG
                     RYNKVANIVGHTMQFHPHGDASIGDALVQLGQKDLLIDCQGNWGNILTGDGAAAPRYI
                     EARLSKFALETVFNPKTTLWQLSYDGRNKEPVTLPVKFPLLLAQGVEGIAVGLSSKIL
                     PHNFNELLDASIAYLRGEEFALYPDFQTGGSIDIAKYNDGERGGSVKVRAKIGKLDNK
                     TLVISEIPYGKTTSTVIESILKANDKGKIKIKKVDDNTAKDVEILVHLAPGVSSDKTI
                     DALYAFTDCEISISPNCCVIKEDKPHFLTVSDVLRHSTDRTLELLREELKIQKQEQEE
                     ALFFASLEKIFIEERIYKDPEFENAKNMDEAISHIDLRLEPFKPRFIREVTRDDILKL
                     MEIKMGRILKFNSDKSNEFIAQTLEQIAKINDKLEHIVDYTIDWFTMLKEKYGKAYPR
                     HTVIRNFDTIEATKVVEANEKLYINRQEGFIGMGLKKDEFICNCSDIDDVIIFYRNGT
                     YKIVKVADKIFIGKDILYVNVFKRNDNRTIYNVIYRDGKFGYNYIKRFAVTGATRDRE
                     YDLTKGTENSRVLYFSANPNGEAETVKVILKPKPRQKLLVFEKNFSEIAIKGRGSQGN
                     ILTKAEVHKISLKQKGSSTLGGREVWFDWDVLRLNYDGRGEELGEFHSNDQILVILPN
                     GDFYVTNFDLSNHYESNIMVIEKYEPSKIWTAVLYDADQKYYYIKRFLLEVNTRKQNF
                     LGENPKNRLMLLTDEVYPRIEVIFGGHDAFREALILDADEFIAVKGFKAKGKRISTFE
                     VETINELEPNRFVPSENASESDDTEGNEEGNDTDDGQSTTDIIDEITGQMKLFDE"
     gene            94286..95155
                     /locus_tag="ACZPB4_00855"
     CDS             94286..95155
                     /locus_tag="ACZPB4_00855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3316 domain-containing protein"
                     /protein_id="HIR1096811.1"
                     /translation="MKAITCLIGLFLLFLASPAKAQSDGDEIPWSINSGTMVGIGSYN
                     LMDTYLSPSMEDKKYTGPGLRVMNERMKRVRLANYRVSRQQIISVDLASTDNAASTAT
                     DFAGFIDYTLGYYYHLPTLLPDLKLLAGGAVHGMGGFIYNTRNGNNPASAKADIDLNI
                     SAMAIYKLRVKEYPMTLRYQFTIPFAGVLFSPHYGQSYYEIFNLGNASGVVQFNSFHN
                     KFAMKNFFTVDFPVCNFTIRAGYLNSSYRTDVNGIQSHIISHSFMIGLVKEFISFGGK
                     RLKNTQRFRSAYY"
     gene            95167..96183
                     /locus_tag="ACZPB4_00860"
     CDS             95167..96183
                     /locus_tag="ACZPB4_00860"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S41 family peptidase"
                     /protein_id="HIR1096812.1"
                     /translation="MKRYLIYICISLGFLFTGCEKSDEYVASPQENFEALWKILDENY
                     CFFEYKDIDWNEVHDRYKTQISDTMNQYVLFDVLGDMLNELKDGHTNLISTFNMSRYW
                     DWYLDYPDNFDSDIQENYLGRNYSIAGGLKYTTLSDGQIGYIYYGSFSSSAGESGLDH
                     IFYQFKDCKGLIFDIRDNGGGMLSNADRIASRFLEEKILTGYIQHKTGKGHDDFSEPY
                     PLYLSPSERIRWLRPVVVLTNRHCYSAANDFVQKVRMMPYVTTMGDRTGGGSGFPFNS
                     ELPNGWGVRFSASPMLDVNKQHTEFGIDPTYKVSMTQEDIEKGKDTIIEAAITHLLSE
                     TEKK"
     gene            96256..96337
                     /locus_tag="ACZPB4_00865"
     tRNA            96256..96337
                     /locus_tag="ACZPB4_00865"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:96290..96292,aa:Leu,seq:tag)
     gene            complement(96666..>97502)
                     /gene="dprA"
                     /locus_tag="ACZPB4_00870"
     CDS             complement(96666..>97502)
                     /gene="dprA"
                     /locus_tag="ACZPB4_00870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HIR1096813.1"
                     /translation="CPDAPVLFYFKGNADLNAAHIISVVGTRRASAYGQEVTERLLRD
                     LSVIFPDLLVVSGLAYGIDICAHRNALKNQLPTVGVLAHGLDRIYPPVHRSTAVEMLE
                     RGGLLTDFPSGTNPDRQNFIRRNRIVAGLADATIVIESAEKGGSLITADIAFSYGRDV
                     YAFPGRVTDINSKGCNGLIRQNKGGLITCADDLIMAMRWDVAQKTDALPVQTQLLFPE
                     NEESERILSFLEMRKESHINELSVALNLPVHQLSSLLFELELDGKIKSMPGSIYKRMK
                     PL"
BASE COUNT        28210 a        24026 c        19158 g        25908 t
ORIGIN      
        1 cagaaaaata tcttgaggca acgattcgtc agcaaccacg tcactggctc atagacaaaa
       61 aacgaaacgg cagacatctc cgccgtcccg cccaaaagag atagccttat ctctgtttgt
      121 acacatgtca aggttggttg tttactgata tcagggccta tataaaccct gtttttcata
      181 tcgtgcgtaa acataagact ttttttcgac aaaagagcag attccttctt ctttttggga
      241 atacatgttc taaacatgcc acactacctc ttggctacta gcgtgagctt ctattataga
      301 ggaactatga aaaagcattt tacatcaaaa cataaagcta aatcctttct tctgcgaagc
      361 attgaaccgt tcaatctcca aagaaaggga tttctttaac tgattagcca taaatattaa
      421 gaaagacctg cgtatgatgc aaattgcctt cagtcgtttt aaggattttc tgaaagaaca
      481 gtagccatta tatgaatgta acatcaagcc cgaacttatt actaaagata tgatggttct
      541 gtttgtagac tatttgcaat cccgtagcgt tggcgaggga gcaaaaagta tctatcagcg
      601 tttcaagaaa gtgatacgct atgccatcga acacgatgtg atactgaaag acccgtgtaa
      661 agaagtaatt tgtaaggtag acgaccaaat gttacggaaa gatgtgcttt cactggaaga
      721 aattcaggct tttatcaact gccattatga gaatgagaac ccaatggtaa gacgtgcctt
      781 tatcttctgc ctatattgtg gtttacgctt ctgtgatgtg aaagacctta catataagaa
      841 tgtagactac tcaaacaagc tattgaagtt tgaacaaaac ggtgaagacc gtgcagccta
      901 tggtgagcaa ctcttgaaga agctggaaaa acggctgaat accaaagggc tgaatgaacg
      961 tcgattccgg gagttcagac gtttgtatct tgtttatcca cagttgaaag aagaggtttt
     1021 aggctatgtt atatcgggtt cgggaattcg gcggttgccg accgccgaat ttgaaacaga
     1081 gattcggcgg tcagtaaccg ccaaattgca agtggtttca gaaatagcaa ataatgactg
     1141 gaaattggct gcagaaaagc tatttaacag attatcttct acgcatttga atgcaatatc
     1201 tgctattgac aatcctatta aacgtgcctt ttatgaaatg gaaacgatta ggggatgctg
     1261 gactgtaaaa gaactggaac ggcagattga ttcattgtac tacgagcgta gtggattatc
     1321 taaaaacaaa gaagctcttt ctgcattagt acagcaacag gcagttcaac tacagcctgc
     1381 ggatgtaata aatactccct tgaccttaga gttcttaggg ttaaatgaac gggcattagt
     1441 tacagagaat gatttagagc aagccatcct tgattattta caaaagttcc ttctggaaat
     1501 gggacacggc ttctgctttg aagctcgcca aaaacgcata ctgatagatg aagattactt
     1561 ctttgctgac ctcgttttct atcaccgcat actgaaatgc catgtcatag tggatttaaa
     1621 aattgacaaa ttccaccatg aatatgcatc ccaactgaat atgtatctaa actacttcaa
     1681 aacagaagta atgcagcccg atgataatcc accaatcggt attttgcttt gtactgaaaa
     1741 aggagatact ttagttcgtt atgccacaac aggattaggc ccaaatattt ttgtacaaaa
     1801 gtataaaatc cagttgccca gtgaggaaga aatcaagaga tttctttcaa aggagatagg
     1861 ctaacaactt tcaataaaaa caaaggttta gttcatttta gatatacaag agaaatggac
     1921 taaacttaat ctgtaacctt ttcattataa aacctcaaaa attccatttc acccacctgc
     1981 tttaaaaatt tctgattttc aataaagtct tgcccatact ttaaccaacg ttttgtaaaa
     2041 cctttgaact tagtgcaagg aaatagatga cattggtagc agtgtgttat tcctttctca
     2101 acgcaacaca ggtaaaatgt tctacatttt tcacagcggg ttttgttttc ctctgctccc
     2161 tgacaatttt tttcatctcg tgtgtagctt ggacaaccgc cacagaacac accacaagca
     2221 ggaatacgac catgatatgg ttttattaca gataaggttt ttgccatcca aaaattagtc
     2281 aaattcaatt tatttgcctg tcgtttttgt tccttcttca ccacgtattt ttgcttctca
     2341 aagaatggac gagcagttag actcacttct gatgtgattt gtataatacc ttttgtaata
     2401 gcatatcgtt ctatttcttc caaaagcata gttgcaatgc ctttgccttg aaagtctgcg
     2461 tgaatgaaca tagagtgcag atagccttgc ggcgtaatgg atgaaaaacc tacaatctga
     2521 gacagttgat taacagccac aataaaatag tgagtcttta tcatttcctc tatattggaa
     2581 agatcatctc cgcatgatgc ccaatcttca acttcatcct gtgaataatc acgcctgttt
     2641 actacaagca cggtattctt atataaatct ctcagttcag cactatcaga ttgttgcgct
     2701 attctgattt taaagtccat tttcatcttt ggttttgtat cttttcgtat aataccttat
     2761 tatcattaag ggttaaaaca tatatctgtt tttccgaatt ttcgttgtat ccatctttgg
     2821 caatggggat cgtaagtctg cctgtaccac agcacagttc aagtatttca gcctccttat
     2881 ttttcggtag ccactttttg tagaattgca aatcagatag aaaggtattt aatccatcat
     2941 atatatttgc atcataaatc aactcaccaa ccttgtaacc tatattcatt tatattctcc
     3001 aatattcatt gtttcatgtt tatataccaa acttatttct attctctttc gtgtccggat
     3061 gggatagtgc gtttatgtca gccctactga tacattcatt aaattgcaag gcaataattc
     3121 gggggtctat cattatctct tctttgctat atttatcatt attaccccat tcggttttaa
     3181 gctgcacata aattatatca tctacccaat ccccacgcaa ataatagctc tccttaaagt
     3241 gagcttcctt tctgaacccc aatcgctcta ttaactggat agaagctgta tttctcggat
     3301 cgactgaggc tataatccga tgtttatcga gcgttccaaa aagataatca actattgctt
     3361 tcaatgcttc tgtagcataa ccttttttct gataatcttt atgtagtgta catccaagtt
     3421 cagcctgcat attgttgtga ttggtaaagc taattcccat atcaccaatt aacctgtttt
     3481 catctgcaag aataatggta aactgaaaac atatattggc aatatccatt gtcgccggca
     3541 tattgctaat ataatcacgg acttcttcaa ctgaatcagg aaaccatccc tgatacttat
     3601 tttccgcaaa gtcagaacgg taagaaaaaa tgctttctgc atcttccggt tcagcaagcc
     3661 gtatgattaa tctttctgtt ttaatgggat atttcacctt gttgtttata aattcatgag
     3721 ttgagcaaag atacaaaaat tgtctagccg tggatagtcc tgccgaataa ttacatacaa
     3781 aaaaagcttg actgattact caatcaagct tttcaacttc agtacccaga gccgggatcg
     3841 aaccggcatg gaagtgaatc cactggtgtt tgagaccagc gcgtctacca attccgccat
     3901 ctgggcattt ttgattaacc ttttagcttt agcagtaggt ttgtttctca aatgcgttgc
     3961 aaaggtacag ctttttttta aacccgcaag cgtttgggta aaaattttca aatatttttt
     4021 tcacagtggg aatatgtatg ggattgtttc gcatagaaag attatttcgt tacatttgta
     4081 aacgtataat cataataaca gccaatatca tgaaagataa ttattgcgtc atcatgggag
     4141 gcgggatcgg tagccgtttc tggcctttca gtagagaaag ttacccaaag caattccttg
     4201 atttttttgg aagcggacgg tctttactgc aaatgacatt tgatcgcttc gcaaaaatca
     4261 tccctactga aaatatatac atcgttacca acgaatctta tgcggactta atcaaggagc
     4321 agttgccgga attagcggaa gaacaaatac ttttggaacc ggctcgtcgc aatacggctc
     4381 cttgtatcgc ttatgcggct tatcatatta aggcatgcaa tccggaagcc aatattgtcg
     4441 tagccccttc cgaccatctg atcttaaaag aggatgtttt cttgagggac gttcaaaagg
     4501 cgttggattt cgtgaagaga aaccgtgcgt tggtcacttt gggcatcaag cctagccgcc
     4561 cggaaacagg atacggatat atccaaagca gtgatacggt agtagatgat ttcaccaagg
     4621 tgaagacctt tactgaaaaa ccggacctcg agttggcaaa ggtatttatg gaaagtggag
     4681 aattcttctg gaattctggc ttgttcgtct ggaacgtgaa tacgatcttg gaagcgttct
     4741 ctaaatatct cccggatatc agcagccgtt tcgatctagg taaggataaa tttaatacct
     4801 cggaagaaaa agcgttcatc caagagaatt tcccttattg cctaaatata tccatcgact
     4861 acggtatcat ggagaaagcg cacaacgtat atatgctatg tgtagatttc ggttgggctg
     4921 acctcggtag ctggggatct ttgttcgacc tagcgaataa agacgaaaat gagaacgcag
     4981 tattgaaaaa taacgaggca atgctatacg aatgctccgg caatgtgatc gcattaaata
     5041 acccgaaacg tctagccgtt atccaagggc taaaagattg catcgtggcc gagtctggaa
     5101 acgtattatt gatttgtaag aaggataacg aacaacgtat caaacaattc gtagccgacg
     5161 ctaaaatcaa atacggaaaa gaatataact aattaagaat tgagaattga gaattatcgg
     5221 caagcggtat tcattctcaa ttctcaattt tcaacttctt agcaagatat cgtacaggat
     5281 accacgcagc caaaaagcct atcgttaata ccgtcacaaa gactgttatt atatcgaccg
     5341 ggactacacg taccggataa gcctctataa taaacgctcc ggcagcttcc cctagtttta
     5401 taaagccaaa ctcttgttgt agcaagcaaa gcacaacccc gatcaagact ccgatcaaag
     5461 ctccaaaacc ggagatcatc cagccttcaa acaagaaaat ccgacggatc agactgtcat
     5521 cagcccccat attacgcagt gtgctcacat cctcctgttt ctcgatcatc aacatggata
     5581 aagaacccac cacgttgaat aaggcgatcg ccaatataaa agtaaggatc aagaaggtca
     5641 tccatttctc gacttgcatc atcttgaaag aagcctcttg ttgctcaaaa cggtcttgca
     5701 cgatatattg atcacctagg atacgttgaa tctctttctt taccggagcg atatccccgc
     5761 tatctttcac cttcaattcc accgctgtca cttctttatc ataattaaat aaagaacggg
     5821 ccaatgacaa aggcacgatc atatatgaat catcgtaaac ctgttggtcc gtacgaaaga
     5881 cagcaccgat ataagcatat tccaaattga aagaagaagc cggattcgcc atgttcacct
     5941 tctcctcccg cttcggagcg tagatctcta gcggagagac gaagccagcg tttattccta
     6001 gcgagaaagc caatccgatc cccatattcg cgtaattcgc cacctcgtca ttcagaagga
     6061 actttccatc gatcaagata ctatcaatct gcgccagttt ctcatattgc tcgtctacac
     6121 ctttcaaggt agctacaccc tgacgatctc gataacggac caaggcattg tcctgcaata
     6181 cctcactaaa acaaacaatg ccgggcaatt cccgcacctt acgtatctct tccgaggtcg
     6241 ggtcgaaaac cttccctttc cgaggcatga tcttcaactc cggatcaaaa ttgctgaaca
     6301 gagaagagac caaatcgttg aaaccattat agaccgacaa ggcgcatact aaggcgatcg
     6361 tggcgacaac aaccccacat accgatacca tcgatatgat atttatggca ttgtgcgact
     6421 tcttcgaaaa gagatatcgc cgggctatat agaacggaag attcaaggct cctctgatta
     6481 cttatgcaaa agattgtcga tattctcgat ataatccaat gaatcgtcta taaagaagct
     6541 caattcagga atcttacgaa cctgcaaacg aatacgttgc cccaaatcaa aacggatcgc
     6601 tttcgtattg ctccgtatag cctccaatag ctcttgcgat ttatccgacg ggaaaatgct
     6661 taaataagct ctcgccacac ttaaatccgg acttacacga actacgctga cagagaccaa
     6721 tacgccatgc attccttgcg tctgcttctg aaatatatca ctcaactcct tctgaagaag
     6781 gcgttcgatc ttttgtaatc tagtactttc catacgcttt attatttact ttttccagat
     6841 catcgtcaag ccgtcacgta aagggaggat caccttctct acccgatcgt cttgcttaac
     6901 cttttcatta aaaaccagta ttcccttcgt ttgtttatcg gaaggatgca cttcttctac
     6961 cactttaccg tcccaaagcg tattatccgc gagaatcaag ccgcccggac ggaccatcgg
     7021 gaataccaaa tcataatact cggaatacag gcgtttgtcg gcatcgataa aaaccatatc
     7081 gaacgtctca tccaaacggg ggataatctc catcgcatcc ccaaaatgga cttttatctt
     7141 gtccttatgt agcgagcggg aaagatattt catgataaaa tcctccatct cgtcattgat
     7201 ctcaatcgta tggatcaacg ccccctcttc catgccttcc gccatacaca aagtggcata
     7261 agacgtataa gtcccgatct ccaagactct tctcggacga atcatccggc aaaacatctt
     7321 caatatccta ccctgcaaat gcccggatag catacgcgga cggagaaggt tcacattggc
     7381 gtcgcgattc aacgccgaca gcaaatcccc ttcttcatct atatgagaaa gaatatacgc
     7441 atcaatctcg cccgtaaaca ttcctcttac tctttaaaag taggcaactg atattgcgtg
     7501 ccggcatcca gcacctttcc tacgttgtta atctccaaaa agctggtacc gccaccttcg
     7561 ccgaagctac cgctcaaata cgctaccata tcgttgcgag tgatacgtcc gctatggatc
     7621 agctggttca acgcatcata gaaatatccc ctacgactgt cgttgtacgg ctgatgaacc
     7681 gcccataccc cataagaaag acccaacata cgcatcacac gaggattata gcatatagcg
     7741 aacacagtag aggttccgcg gaaagcggcc agataacgtg ccgtacgacc cgtataacta
     7801 tccgtgataa tcgccttcac atgtaattta gaagaagact taacggcttg tttcgccaag
     7861 aaagaagtca cgtctaaatc attcccctcg atcggcacac ggatatcatt cgcggaaagc
     7921 ttggtcttct cggcttcacg agccactttc gtcatggtct gtaccgcctc gatcggatat
     7981 tttccataag ccgtctcacc gcttaacatc aaagcatccg tacgataata aatagcgttg
     8041 gcgatatccg taacctcggc acgagtagga cgaggattat taatcatgga atgaagcatt
     8101 tgcgtagcca cgataaccgg cttcttcacc tccacgcatt tacggatcag catacgctgg
     8161 atacccggga tcttctcggc cggaacctcg atacccaagt caccacgagc gatcataacg
     8221 ccataagcca cttccaaaat ctcctcgata ttgtctacac cctcttgatt ctcgatctta
     8281 gcgataatct tgatagggct gttacgctcg tccaagatac gttggatatc caatacgtcc
     8341 tgtttgttgc gaacaaatga gtgagcgata aaatcgagat catgatcgat cgcccaaagg
     8401 atattattac ggtctttctc agtcaacgaa ggcaaattga tacgtacgcc cggcacattc
     8461 acgctcttgc ggctacctag cgtagcgtca ttctggatat cgcaaagcaa acaatcgccg
     8521 gatttcccga taaccttcat ttccagatca ccatcatcga taaggatgtc gctgccaatc
     8581 gccaagtcgt tcacgaaatt cttatatgac acacaaatac aatcatgcga agtttcctga
     8641 tcgggattac cgattacctt cacgatctct ccagtcttga aagggatcgg ttccttgttt
     8701 accgtcgtcg tggtacgtac ttccggcccc tttgtatcca tcaagatacc gatacggtcg
     8761 gatactgtac ggacgttatt taccacacgg gtcaacccct cttccatcat gtgagccgta
     8821 ttcaggcgca ccacattcat tcccgcttta tataacgcct caacgaacgc aacgtcgcag
     8881 cgctggtcgg aaactgtagc aacaatcttc gtatgcttta acatatacct taaattatta
     8941 taacctaatt attaattcta tttgataacc ttctaaacct tctatcacat aaacgattcg
     9001 atcgccaacc gatacgaatc cagcccaaac ccaagaatca ctcccctgca tgccgccgat
     9061 atcatcgaca catgacgaaa cgattcacgg gcatgcacat tcgagatatg cacttccacg
     9121 actggcgtag taaccgcctt gatagcatcg tgcaacgcaa tggaagtatg cgtataagcg
     9181 ccggcgttca acacgatacc gtcatattca aaacccacct catggatctt gttaattatc
     9241 tctccttcca cattactttg ataataagat atctcacact gaggaaagcg ggcacgtaac
     9301 tcgctcaaat agtcctcgaa cgaggcattt ccgtatactg tcggttctcg cttgcccaac
     9361 agattcaaat tagggccatt gatgatctga atcttcttca ttcttaattg taagtttatt
     9421 acctttgtac cgcccgttga ggccggaatt atccggcaaa ggtaaggatt ttatttgaca
     9481 cattcataac gacataccga caatgcgaca aggaaaagat ataataaacc gatataacac
     9541 ctatttacga ttagaaaaat cgctctcagc caactccatc gacgcctatt tgacagatct
     9601 tgacaaattg ctacgtttcg cagaggatga gaaaaaggac gttaaggaga tcagctacga
     9661 cgacttgcaa cagttcatcg cccaattacg tgacatcggt atccatcccc gatcgcaagc
     9721 acgcatcatc tcgggtatca aatcgttcta tcgtttctta ttgcttgaca attatataac
     9781 aaatgatccg accgaattgt tagagtctcc caagatcgga ttgaagctgc cggaagtatt
     9841 aaccgtcaac gagataaata gcattctcga cacgatagac ctcacgcttc ccgagggaca
     9901 gcggaaccgt gcgatgctgg aggttttata tagttgcgga ctgcgcgtat cggagcttac
     9961 tggcctgcgt tattcggata tatatcccaa ggaaggtttc atccgggtag agggtaaagg
    10021 aagcaaacaa cggcttgttc ctatctccga agttgctttg cgggaaatta aaaactatct
    10081 gtatgaccgg aattcggtcg tggttaaaaa aggcttcgag gatattttat ttctaagccg
    10141 gcgaggaacg gccctctccc gtatcatggt atttcatatc attaagcaac agacagaggc
    10201 cgccggtatc cataaaaacg taagtcccca taccttccgt cattctttcg ccacccactt
    10261 gctggagggc ggcgccaact tacgcgctat ccaagagatg ctggggcatg agaaaatcac
    10321 caccaccgag atatatacac atatcgaccg ggaattcctt cgcaaagaga tactggaaca
    10381 tcatccgagg agtaggccaa gaacttaaaa gaaccgatcc tgctccgcta gcaaagcccc
    10441 aagaatgtca taaattattt atttcctcct ctgacaaacc agtataacgc acgaccattt
    10501 ccatcgaaag cccatcagac cgcatacgcc gagctgtttc tagacgttct tccacacggc
    10561 cttcttccca gccttcaaac ttagcagtgc tcaacacgtc attctggatc ataattgcat
    10621 tcagatgttc gtcataagca taacgttcct cgggagacat tgagtaatag cgtaatttct
    10681 ctcgtgcctc ttccaagccg ggggctgtcg tttcggaagt tatgatcccg tctttcaagt
    10741 atcgcaccca ttcctccaag ggggtcacgg cctccttatc aaactcattc acccgaacca
    10801 atatatactc cggaaagatc tccgaaggaa gacgcttgac gatcacaccc ctctccttgg
    10861 tatttacctg taaatgatca tgggtatgca cgccgacaaa ttggttctgc ccgtgataca
    10921 gataatcggt tcctacgcct atatcaaaat aaaggatact gatagaatag atctttttca
    10981 ccccggaata gtcctgcccc aaatgaagat gctcggtgac ggccttcgcc atgccataga
    11041 gcacacgttc caaataataa agctcgcagg tattctggat ctcgataagg atgatatctc
    11101 cctttgtgtt cttagccttg atatccaccc gattgaattt atcatcagcg tcctgctggt
    11161 tcccctcact ctccaatatc tcctcaatct tgatctgctc gcccaagaac acggtaagaa
    11221 agccttctag cactccgaaa ttcgcttttt gccggagtag gcgtttgatg gcccagtcga
    11281 aacggatata ccgatcttgt aattccttca tatacttctc ctctttttct gttttctttt
    11341 ccatagtcat atcatgtttt agttatccca ctattgggtg gcttcaaatg tacataaaaa
    11401 gatccggaat acaagcttat cccatctaaa aagaaatgtc cttctttttg gatccgtaag
    11461 tgaatagcca acgaacggaa tcgtaagcgg tcgcaaatgg gtattcgtgt accgttatta
    11521 ctctatttta atctcatatt ttatcgattt aaactattta cttaaagaca aaaaacatgg
    11581 atgtggacaa atgatcacac atccatatct aattatcaac aaattaaaag ctatcaggtt
    11641 ctcctaaaat gaacaaatgt aaatacagct caattcttag aaatgaggat tctgtaccaa
    11701 atggccatcc gacttatcaa tctccgactg aggaatcggc aagtatttct ttgtatcatc
    11761 ccagcctttg ataaaatctt tcgcttggtt cgtacgtact aaatcccaat aacgaatacc
    11821 ttccatcgca aactcataac ggcgttcctt atagatatta tccaatgaaa ccgtcggaac
    11881 cttataatca tcacccatcg cacgtttaac gactctcgca taataatcct gtgcctcgcc
    11941 aacgctacct ccacttctca ataaagcttc cgatgccatt aatagtatgt ccgagaaacg
    12001 aattacacgg taattgtttt tataattcaa cgcttccgta ccaaccgtag aagaataccc
    12061 tgcacgagga tgatatttgc gtacgctata ccccgtatat tgattcacat ccgagctaat
    12121 cgttccgcct tccgctctaa actcctcatg atctatgatc gttgtccact ttctaggatc
    12181 atccggtaaa aacgcatcat tcaatgcttt tgttacaggc gcaaaccccc aaccttccac
    12241 atacacatta ttgggatctt tcaaacctct ggctcctagc attattatat cggagttacc
    12301 ttgattggcc ttgcctgccc agtcattcga gttcccgatt tccgtataat tgacttcaaa
    12361 aacagattct ttgcaccact catactcatc atcaaaaagg actttataat ccggaatcaa
    12421 gtcatattga taggcaggat cggtaattag ctctttcaat tggctggcga tctccttcat
    12481 tttagtatca tcattctgat aaagaacgat acgtgctttc attgcgatag cggcaccatt
    12541 cgtagctcgt cctttctcat tagccgggac taccttgggt aacttcccaa taacgttatt
    12601 atctaaatcc tctattaact tcgcatagac ctcatccggt tgcaattgag ggacagttgt
    12661 tatatcatcc aatcccaaat tcgtctcgta atacggtatg tatccaaaga aacgccacaa
    12721 ctggaaataa taaaatacac gtaagaaatg agcctcagct acataacgat cacgaagctc
    12781 cgccgacatc gtcccctccg gaagaagagg gcatttctct atcacgatat tcgcacggtt
    12841 tacaccctca tacgaacgcc cccataaacc ctcgggtaag tttgtcggtg tcacccaatt
    12901 ggtaaaatca ttcactcgtt gcaactgcgg ttgatccgat accgtcgatc caccggtctc
    12961 cgcatcatcc gacatgatat tactaaccag ttcataagag ctatacgcat tataagcgtt
    13021 ccatttcaac gggtcatagg cagcgaccaa tgcctcggtc aaatcctcct gtgtcttgta
    13081 ataatccgtt tcgataacct tattcgtcgg agacaactcc aaaaaatcat tgcagctact
    13141 tagtccgaat acaacggcta gcagataaat atatttattc ataacactaa ttttaatgat
    13201 taaaatgtca aattcaatcc aaatgtataa acccgggctt gaggatatac acccttatct
    13261 atacccattg ttgaaccaat ttccgggtcc atccctttat atcccgtaat agtcaacaaa
    13321 ttatcgaacg acgcataaaa tctcaagcgt tgtatataag ctttccgggt caactgagcc
    13381 ggtagcgtat aacctacctg taaattacgt aagcgcaaga aagaagcatc gtgaaccaac
    13441 aaagtagacg gacggaagtt cttaggcgta tcacctaaca caatccttgg catcgaattg
    13501 gaggtacccg gtccagtcca tcgctccaaa gcatccgacg tataattgac tgccgccaac
    13561 tcataacggc gtaacgcatc gaaaacatcc gctccaaaag aaccttggaa aaaggcactt
    13621 aaatcaaagc cattccaatc agccgcaacg gtaagtccaa ccatccaatc cggattaggc
    13681 ttgcctatca tcgtacggtc ctcgttatca tcgctgatca caccgtctcc gttcaaatcc
    13741 tcaaatttcg tatcaccggg tgccgcattc ggttgtatag gcttaccggt agcaggactg
    13801 atatagctat cgatctcctc ttgtgtctgg aaaaccccaa ttgccttgta tccgaagaaa
    13861 taaccgattg gataaccatt ttcgttcctt gataccgtac ctaaagttgg taaactctct
    13921 ttatcaatat atcccgtctg atttcccaga ttcttgatct cattcttcac ataagaagca
    13981 ttcgccaaga aagatagatt cactttatct acacttaatt tataaccgac ttcaagctcg
    14041 ataccttggt ttgtcaatgt cccgacattc gataaaggcg agccacttcc cacatatagg
    14101 ggtatcggac gctccatcaa catgtctttt gtatctttct tgaaccaatc aaaactaaaa
    14161 gaaagggagt tattaaagaa gcgagaatca aatccaaagt ccaattgctc cgatgtttcc
    14221 caacgcaaat caggattagc caaagaagta ggctttgttc cgctatgaat gacaccgttc
    14281 gagcttaccc cgaaactata gttatttcct ccggtcattg tcgtagtata tccaaacgat
    14341 ccgattttct catttccgtt ctgtccccag cttccgcgca ctttcaagaa gtcgaaccat
    14401 cccggtttat tttccatgaa aggctcgtta gtcaacgtcc agcccgcaga gacggacggg
    14461 aaataggcat attgattatt ccggccgaag ttagaggaac cgtcccgacg aagggttaac
    14521 tcaagcatat acctttcgtc ataattatag ttcaatcgtc cgaaaacgga ggccatccga
    14581 tgctccgtcg ccccaccttc cgaatgctga tcgccgggag aggcactatt ggtgaaatcg
    14641 atccacgctt tatgatcatc ttccgctcgt aagttcaagg ccgttccctt taccttttta
    14701 ctatcatacc gttccataga ggttcccagt aaaaccgcga aattatgttt atcgatcgaa
    14761 cgtttataac tcaacgtatt ctcccaaaga agtttcatgc cacgattcat cgtttgctcc
    14821 accctcgatt tctcattctt gaccatataa cacaaataac taacagggaa ccaattcctt
    14881 tcgccccaaa aagccatatc cgtagagaga gaggtcttaa acgtaagatt ctcgaatact
    14941 tccaattcac cccaaacaga tcctacaaat ttatcccagt ccttgttatt gtttaaggtc
    15001 tgcatcatag cgaccggatt cacgatctct tgattttcga tcacgttata aatacggcct
    15061 tcgtcatcct tgacataacc gggataattt ttttcgtaat aagcgagatc ttccgccgaa
    15121 ggattctcca gatagaccga ttcgttcggt ggagtcatca ccgcacttgc caacgggccg
    15181 gagaagttgt cattctccga aatacctttg gatatgatcc gtgtatatcc taggttcgta
    15241 ccgaccttga aactacggaa gaatttattc gtcttattct caaacacatt ataggtattg
    15301 ttgaaacgta agctatatcg tttataatcc gacttatctt ttcctccaac aattccttct
    15361 tgatctaaat aaccaaaaga aaggaaatag cttcccttat caccaccacc actgatgctc
    15421 gcttgatgat tcatgatcgg ggcattctcg ttataaatct cattctgcca gttcgtccct
    15481 acaccagctt tcgaaggatc atcgtaaata gggtccatcc cggcattcac gtaagcctca
    15541 ttcattattg tctcatattc ggtggcattc aagaccgaca tttttcnnnn nnnnnnnnnn
    15601 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15661 nnnnnnnnnn nnnnnnnnnn nnnnnncaca tatccaacgc catcgctgat ccttactttt
    15721 ctttttcata aattattcga atttaaaggt ttaaacaata ttcctaacat tactttttgg
    15781 ttattcggac tctgagtatt ttcaaaaaag gggtagcatt cccctcgaca gcactcacga
    15841 ggagtgccgc cgtaggaaat tggatataaa agctaaccta actaatttaa tgtatactca
    15901 aagtaatcct tgaaagaggt taccgcatcg cctactttta gataacggcg actaagtact
    15961 ggtttcgccc cccccttctc atgatactcg gctatcaaaa gataacctcc tgcttttgag
    16021 ggcaatttca gaaggcaagg ttgaagccgc ttgccaaaag gttcaatcac aatagactct
    16081 tcttgtgtcg aaataatagt tcctttctcg tctagtagtt tcaagagaac ttttcctgac
    16141 gagtctttat tcaagtcgtt caccccaacc aagttgaaga ctaaatcact acccggtttc
    16201 aaggcaggga gatgttttgt ataacgatgg tccgtcaagt cgataaagac cgccgttgga
    16261 gcgaagcaat gcttgaacca ccggaaagcc ggcgaaggtt gcaagtcctt aatatcattg
    16321 ataaaccaat ctcccgtgaa accataatta ttggtcagat ggcaaaaggc caagattcca
    16381 cccaccgagc gttctgaacg cagccactcg gtctcaagct gtaaccaata ggcttgcaat
    16441 tcacggcatt gagccggagt agcgttctcg ccgagataat aattataatt attgagtgtc
    16501 aatttcgagg gccgtccatc acgccataac caaatccatc cgtactcatt gaccaactga
    16561 ggaacgcccg catctagtat agaagagaaa cctacccaat tctcatgcaa tgcacctaag
    16621 ttatagggat tgtttttgaa gtagtcgttc agttcactgg aatgcatcaa cgttagcgcg
    16681 cgatatgggt gtggctcatc catctcatca ttcgttccca tctgatcaga tgtcatatag
    16741 ccggcatccc agatccgggt cgggtctaat tcctttagtt cgggaatcag cgtatttcct
    16801 atataactgt cccaattctc attgatcgca tcccagatca cgatactggg atgattgcca
    16861 tcgctccata cccaattcgt atactcctta cgtacctgtt catcccatcc atgattttgc
    16921 caataaagcc actcattttg caatacgatg ccatactcat cgcaaagatc ataccagaag
    16981 tccggaacaa taccgacaca tattcgcata gcgttccaat caatcgactt tggcaagtct
    17041 atcatcagct tcttcaccca ttcccgatcc caagccaacg cttgacaatc cgggtcctca
    17101 aagaaacgtt gaagcgtgat attggagcct cgtaagtaga atttatcccc attaagcgta
    17161 aagaatttgc cttttctcga aaaatcacgc atcccgaagt tcaccgaata acgatctaca
    17221 agctcatctt ggtcatacac cgagacctcg ccttcgtaca agaaagggga atccggagtc
    17281 caagccttcg gattatccaa agagatactc gtttcgaaat aagtcctatt atcccgttta
    17341 acctcacctt caatcacttt ctttccaacc acctgccctg tggtcttctc cttgacacag
    17401 aactcaatct tacaagagtc cttcatttta tccccataca acatttgggg tggatacaaa
    17461 cttctcacca aagtcttaac tgtcaccaat cctttagcca gagaaggtag gaacaaaatc
    17521 ttgtcgaccc gcatcttacc ggtagccgtg atgaacacgt cgtcccagat tccgggtagg
    17581 taatggactt tctccttatc cgtaccaccg gcagcctcgc taggcaacca cgcccggtcg
    17641 cccacctgaa ttaagatctc attgtccgag ccatatttta cggcactcgt aatattaaaa
    17701 tccattggag tatagcattc catggaagac cctacttgat gtccattcac gaagactcgt
    17761 gtaacgtatt ggcttttctt tatcgtaagg aataattgct catccttgaa tttctcgtcg
    17821 ataaatactt ttcgcttata ccaattatac attggcgtat aatctctctc caagaaatta
    17881 aactgttcca ccaactccac gccgtcaggc ttcttgaaga atttctcgta ttgagaaatt
    17941 ttcggcctag ctagatgcac caatcccgga accggtatct tacgggtata tttccgtggg
    18001 ggaaaagcat gttccgtctg atcaaaatcc cattccccat ttaatgagat cgttgtcctc
    18061 ccgtcatcgg cccaagcgaa tacggatagg aagcaacaca taattaaaat tattcttttc
    18121 atgacatccg atttatttaa ctctttcacg aaggcaagtt acaattatta gaaacataaa
    18181 ctttttagaa atttacctcc tgcttttaga atcttatcaa aatataagaa tcatcgtaat
    18241 acataccatc ccaagattaa agtcgtttca ataatttggc tgctacttca ttattcttcg
    18301 tgagagactc atccagcggg gaagaacgga tgatagaagt caagcgttta tgccattcca
    18361 catcccgcca cattccagca aactgaggcc cgcaaaaatt actggtcgct acgccgaccc
    18421 acatacccgt acgagctgcc gtaatagttc ccaactcgca gagatctttt acccagtccc
    18481 atttcaataa aggccaatcc ttataatcca ccaatcccca acactctgtc gtaacaagag
    18541 gacggcgatt cttccgggcc acagaagcca taagctctat cttatcagtc aacaacttct
    18601 gccaatatcc aggtctttcc cgataaaccc gttctgcgtt tttcaccaca ttcttataat
    18661 catccggtaa aaaacgattg tagccatatc ccaccagctt ataaaattct ccaccattct
    18721 gttgggccat ccaaatatga tgctcataca aatcaagaaa agagcaatcc acctcttcat
    18781 atttcttgac atccccatga tcaaaagaat ataagaatgg catatccgga tatacttgtc
    18841 gcatcttctc caacgaggtt ttcatccatc gtaaggattc ctccttatac caattccccc
    18901 aaccgacatt cggatatgtc ttagcgaaaa aaggagccca cgaatcaccg ggccactcat
    18961 tgcaaagatc tacataaagg atcgtatcca ataacccatc ctcctcgatc gaacgaaggg
    19021 ttgtcagcca gcaatccgcc aatttctccg gtgtatccaa tttcaggcaa acctcatcca
    19081 catcgagacg ataccaagaa gaaagcccga ccttaatatc ccgctcctta catttcgaca
    19141 agaacaagtt caaattcggt tgaacttgta cctcattcat atccggactt ccccaatctt
    19201 gctgattcca aacttcttta agtaaccatt tcttcattgg attctccgct attaaatgag
    19261 gataagcatc aatacgtatc gcattatacc cccgttccga gagctcgtcc aatacttggt
    19321 cccagtcctc ataaccggct ccgggccaac gcctctccaa ccaagaaaaa tcccacatgg
    19381 tgattgcccg gggcgagatt tctcctttcc cggcaaaagc catttcactt ttagctaatg
    19441 catttgataa atcaaaagcc actaagccgc ctaatgccgc aactgctgtt tgtctaataa
    19501 atactcttct atccatatta tattatttta tctttcgggt gtcctccttt tccccaaaaa
    19561 gcctcgatat tctccaatga aactcctttc gtttccggta catagaaata tccccaaata
    19621 atcgccacaa ttccaataaa cgcataaaat aagaacgctc ctgccggatt cccttggctt
    19681 tcgccattga tcgttaaatc ggttcccggt attgagaata ccttcagtat cttgaaaaag
    19741 gtaaacgata cgatcgcatt gaaaaaccaa acggacaatg aaccgagaga agccccccag
    19801 ccctcttaac ttttgtggaa acacttccga cacaatcaac caacctagag gcccgatgct
    19861 gatagcgaaa aatcccacat ataagaaaat aaggacaatg gaaagccatt tcccggaatc
    19921 ccctaattga gcggcgaata taaaagaggt agcgagtagc gacaaggaaa tcacgatacc
    19981 gctcaacccc agaaaataaa gtttacgcct tcccagccga tctacgaaat agacagacag
    20041 taacgtgaac aataaattga caactcccac ccctacagaa gccccaatcg cagagaccgc
    20101 accatcgaaa ccggccatca agaatatttt aggactataa tagatcaccg tattgatacc
    20161 tacgaactgt tggaagaaca tgataccaat agcgataacc aacgcattcc tcaaccaagg
    20221 ctgagccaaa tccttaaaac gcccttgttg ctcatcattt ttccgcatct cattccgcat
    20281 ctgctcaaat gagacattta cttgatccgg gtgctcgatc atctttaaga ccgataaact
    20341 ctcctcctcc ctgccaacgg acatcaacca ccttggagat ggtggaacca gcaacatacc
    20401 cacgaacaaa ataatagcgg gaatcacccc cacataaaac atcggcctcc aacatgaaac
    20461 agacgtctca tccgcaaaat acaaatccga aagataagat accagaagcc cgatcgtaat
    20521 catcaattgg aacatggcga caaacatccc ccgtgatttc gccggagaaa cttctgcgat
    20581 ataaagaggc accgcaaaag aagatatccc gatagccacc cccaggaata aacgggcggc
    20641 gatcaaatga taaatgcccg gagcccatcc cgaccataac gcaccgatag cgaaaataac
    20701 agccgaagtc aaaatgactt tcctacgccc tatgcgatcc gtcaacttac cacaacacag
    20761 cgctcccaga atagctccca gcaaaccgga ggaagtaacg acctccacca tactatcgtc
    20821 tatgccaaaa tctttctgga agaaaggaat cgccccggaa atcacgccgg tatcaaaacc
    20881 aaacaatagt cctcccatgg cggcgacaat cgctatcaca taaatcatcc aatatctata
    20941 actcgtgttt ctcatgtttt tcttgtgtat ttaatccatc tataaactca aggctcgaaa
    21001 tcacgccaga cctccgcttt caatgcggga ttaggcacat ataagaaaat ctccggattt
    21061 tcctcgaatt gtctgtaaat agatacccct ttccgaatat ctaaagaaat ataatccgaa
    21121 ggagatttac aaatcaaatg agaggaatcg tacatcggat tcgcaatcca ttctaattca
    21181 tcgcttccat taaatatagg aaaccaagcg attcccccgt gtttacgaac cccctcatac
    21241 acaaaaccat aatctctatc gcaccacgcc ccgaaagtca aaggcaatct cggattcgca
    21301 ctaatcgtca catgtaccca atagggagga acgatcacta catcccccgg aaaggcatgt
    21361 accgcataac atcgaccggg ttgatcctcc gcatactcct gcatataaat aatcgcctct
    21421 cccgaccaaa tctcatagat ttccggcgta gaccaaccgc tataaggaga tatcttatga
    21481 atatgccctt gacttctgac tggctcctgc cccaatttac cagcgctata tgtcactacc
    21541 ccgaataaca aatgtaactt attcagcaac acacgatgtt cttctttgcc gacatccata
    21601 gcgatcgagt aaacctgctc cggtcccttg cattgaggat cacgcaaact agcccgtata
    21661 tcttccagcc ggcgaatctc gacctccgga ccaaatacac ccgccccata ggtaaacccc
    21721 ataggcgatt gaaccggtgt tatatcaatt cctttatcaa atacaaatcc gttcattttg
    21781 ctgttgtttt accatgaaat actccaagcc gaataaagcg gcgtcatcgc ccaatattgc
    21841 cgggacaacc gggactttcc cggaaggaca ccaagctaat tcatccactc gcttactgat
    21901 ataaggaatg attacctctt ggctttttaa aatcccccct cccagaatca ccacttccgg
    21961 atcataagca tgtatatagg ttattatcgc cgatgcccag atatccatgc attcgtttct
    22021 aatcaataaa gcgtctgtat tcccctcctg cgccaacctg aaaatgcgct tgaaatcata
    22081 gatatccgca tctcgcttaa atgattccga taaaagggca tgctcccgga taatggtcgg
    22141 caagaaaaaa gaggaagaca gagcttctac acagccttta ttcccgcatg aacatcgacg
    22201 gcccttataa tccaacacaa aatgtcctcc caaagaaccc gcttgaaaat gctgtccata
    22261 cagaagccgt ccatcgatca cgactcccgt accgataccg gttccgattg tcatcatgac
    22321 tacattgttc tttccccggg ccgcaccctg ccaccattct ccggctacgg ccaaacgagc
    22381 gtcattatcc atgcagaaag gaacttccca attctcccat gcccatttat ccagactgat
    22441 cgaacaggca tcatcatact tctcattcgt agagattacc cggttatgaa ttggatctac
    22501 caacccggga aaagccaggc cgatacaacg aagcgccgcc acatcaatac gccaagcggc
    22561 caacaaccga tcgatcgcct cctttatctt aggtaagttc agagctaatc ccagagccag
    22621 acgggaaggt aatctcacac agtctacgat ctcaccatca gacaatagtc cgatctttac
    22681 gaccgtcccc cctaaatcta tcgctatcgt atacataagc tatcgcaatt taggggtacc
    22741 gttcacttct accaatcggg ccgagaagcc cttattcgct atctcttcat aattatgccc
    22801 ggcatccgaa ggccagcatg cggcaaatga caagacgcta tttccagtat tagctacccg
    22861 gtgcgctaca ccgcccagta tataatgcag gctacccggc atcatccttt ccgcccacgt
    22921 attccgttcc cgatccatca agatcaacat accttcgcct tccaatcccc aataatactc
    22981 cgaacgatcc tcttgttgat gaaaatggcc tttcgtcatg aaatactcat ctcccacctt
    23041 tcccggatat aattgagtaa taccaaaata aagccctccc ggagtgcctt cccgctccgg
    23101 taaataacta tatacctcgt atgctaattg atctaatggt aattgggaat aagcatcttg
    23161 attctcaaaa attccggcaa gctcacctaa agttctccgg ctctttacca caccttcccc
    23221 ctttaactca ttttgaaaaa atgacaagga tgggattaca atctttttat gttccatgat
    23281 attctatttt acgatacaac ttatatcgca aaaatagatc gaataccttg ggctttattt
    23341 tagtattttt ccaaacaact atgaaatcct gtccttattc tccatccagg cgctccttat
    23401 attttttctg gtactcggat ggaagcatat tcgtggtttt cttaaattgg ccgatgaagt
    23461 tggatagatt attgaatccg gcctcggaac taatcgtgga tatcttcagg tttccctcta
    23521 tcaatagttt tttcgcatgt cctatgcgca tgtcattcag gtactccacg aaagtcttct
    23581 tggtccgttt cttgaaataa cgacaaaaag cggtcggagt caagcctacc aaagcggcga
    23641 cttcctccag cttcactgga gacgtgaagt tcttcaccag atatttatag accttattga
    23701 aacgctcgaa atcgtccgag ttgaccgttt ccgtaaaccc cgtactggct aatatctcat
    23761 attcttcgga agtcgccatt aattccagta aagcaatcaa tttgatcacc ctactcgctc
    23821 ccgtctcatt ggcggattgg ctgatcagct cggcaatctt cttccgggac ttacccacaa
    23881 acttaattcc tctacgggaa cgctctatca attcccggat attattcatc tccggaagac
    23941 ggattaaatt aggttcaaaa atctgacgct tgaagaacaa gcaaatacaa gtagcccgca
    24001 agccggagct cttatcgaaa taaacagggt cgtttctcca ctcatgtggc agttgagggc
    24061 cgatcataca aacatcgccc tcgaaatatc cttccacatg atccccgaca aagcgagtac
    24121 ccgtaccact tgtgatatac attatctcaa tagccggatg gtagtgccaa ggcactataa
    24181 aatgcggtag atcctccaca tagaaatgaa tgtgactatc tatcgggaat ggcagttctt
    24241 gaaataatgg tttcataggc tttatactaa aggtttcaac ctctcgatca gttcatcccc
    24301 aagcgcccgt ttattcacga tatgttcctg tacggcggta acaaacggat tattcacgaa
    24361 atctcctcga acaccctcga aatcctgttg tttttccttg ttggaaccat ccacaccgaa
    24421 accgatcata gaagtcaagg agaattcctt acgggcatcc tcataaagca tctcatccaa
    24481 gcggatcaca cattcttgcc aacgacgaac cagatcaata atctctgcgg cggaaatcga
    24541 acggagatcc accccataat aacgttcgat catctcgtag gcccatgtcc attccaagga
    24601 ataataacgt ccgtgaacca aacggaaaaa acattccaca tcctctaagg aagcgatttc
    24661 cccctgttcg atatcttgca acaaggcatc tagcggttcc ctcgggagga tcaagcccgc
    24721 caagtccagc cattctccgg agcctttgga ttccgtagga cgcaattgct cccagacctc
    24781 ttccatagaa caataggtcg taccttccaa acgcttgatt aacgagttac caaagaactt
    24841 attaattgcc atcccataaa agttcaacgc attccggagg gaggaacctt ttatacgagt
    24901 attctgataa taataaatct cggaagtctc tccaaccaat gcctgcaggt ttttcaagat
    24961 atccaccgct ttcagcatct tctggatcgt atagggactc aatagattat agttaatcat
    25021 atccaagcga tccgggtccg tacgtttatc acgcttcggc catttctggg catcacggat
    25081 cgtacctacg ctgcgaagat taattcccgg gactaagtaa gtctcatcat ccttctctat
    25141 taaataggag aagggaatat cggaagtatc gctatggtga tgatggcgac ccattaccaa
    25201 agagaaagcg ccgatacggg ccggccaaag aatatacgag tcgctggtag tcttggagcc
    25261 acgttccacg atcccttgat ggatcggtcc cagcttatac atatgattac tctggttgga
    25321 gccacttccc gcgttcaaga acgaatacat tcccgctatc agcaaactgc tcttatgcat
    25381 agacaccgta aacggaccgg cgaatatagc gcaagcctcc ccattctcga aagcgcagtt
    25441 gctgaacaac aaggaatcat gggccgagaa gttatgcgtc acttggcaag cctgtccgat
    25501 aaagcaacgg ataatcttag cggcatccgc gatcttggct cccgaagaga caatgaaatc
    25561 ttgcgcaatc acactatccc cgataaatac cggggcctct ctcttactat ttacggaacc
    25621 attttccaga cgtgcgctat tctctatggt cgcataatca ccaatcttca cgttacggat
    25681 cgtaccggta ttgacaatct tgaccttatc gccaaccgtt ccctccgtag aggcgatacc
    25741 ctccgtataa gcggtaatca tatcccgcaa gcgttcgatc aaggccggac gatggcggta
    25801 caaagcgata atataagcca atgaagccga caggccatcg taaatcggaa cctcacgccc
    25861 gccggtctca ttcaagaccg acacctcgac attattcccg aacgtagcct tgccttccac
    25921 caacataaca tttatattct ggataaagca gtcatcaccg atccggtaat tagcgatata
    25981 attctgtacg ttctcgatca gcacattatc ccccaacgta caattatgta gggtaacatg
    26041 acgaagcccg ctatgcttta ccaatcctcc cggcagggta aacaccttac gaaaggctcc
    26101 taacctaacc actcctgaaa aacgtacgtg gttcacatat tcaatatcaa acacctctgg
    26161 aacccaaact tgattccaat catcggcccg gcaagcctga gatcgcaagg tggcgatctc
    26221 atccggccgc aaatttctca aatgattcat tggtactaat tttgtaagac tctactcttc
    26281 atcatattgc tgaaagagga agtcattgta ggggaaacgg gtgatatgga tttgtttgac
    26341 ccgttcatac aacatctctt tcaacgcctc tatattcgta cgttccttgg cggagataaa
    26401 gatgcaatta tcttgcaatt ttcccatcca cgtacgtttc agttcatcca gatcgatatt
    26461 ctcacgacca cgaggggtca aatcatcttc ctctttcggg acaaaggtaa atgcgtccac
    26521 cttattgaaa accataatca tcggtttctc ggtcttatcg atctccgcca acgtacggtt
    26581 cacgacctct atttgctcct caaaagtagg atgtgagata tccacgatat gtaccagcaa
    26641 atccgcctcc cgtacctcat ccaaggtcga tttaaaagat tccaccagct cggtcggtaa
    26701 cttgcggata aatccgaccg tatcagacag caagaacggc aagttctcga taatgacctt
    26761 gcgtacggtc gtatctaacg tagcgaacaa cttattctcg gcaaagacct cactcttgct
    26821 caataagttc atcaaggtag atttacctac gttcgtatat ccgaccaacg ctacacgtac
    26881 catcttaccc cggtttttcc gttgtacgct tttttgcttg tcaatatcca ccagctcttt
    26941 cttcaatcgt gcgatcttat ccaagataat acgtttatca gtctccaact gtgtctcacc
    27001 cggaccacgc atacctacgc cgcctcgctg acgctccaag tgtgtccaca gacgagtcaa
    27061 gcggggtaac atatatttat attgtgcaag ctccacctgt gtcttcgcat gggcggtctg
    27121 tgcacggcta gcgaagatat ccaagatcaa gctcgtacga tccaagattt tcacctgcaa
    27181 ttctttctca atattacgga gttgcttcgg actcagctca tcatcaaaga tcaccaaacc
    27241 gatctcattc tctaccacat actccttaat ttcctgcaat ttaccggtcc cgacaaaagt
    27301 gacggaattc gggtaatcca ttttctgggt aaaacgcttt accgcatcca cccctgccgt
    27361 atcggccaag aaagccaatt cgtccagata ttccttaact ttttgctcat tttgctcagg
    27421 ggtaaccaaa cccaccaaaa cggccttctc ggtctgtgcc tcagatatga taaattcttt
    27481 catgccacaa agatatatta tttcaattat ttacgtatat tcgcgaacat atttacaaat
    27541 ataaatcaac ttagctatga aaaagagaat ttggcatcta tccagacgcg ttgtcgtttg
    27601 tacggtattc ctattcgtac aacaatttat ccagtcacaa gtttcaaatc cgtctacatg
    27661 ggaaagcttt gtgcaaagta acgcaaatat atctattcga gatacgtttc ggatgcagac
    27721 atttgaggga cttgcttctg ataattggga ttatgccatt acaggtgaag cccttattga
    27781 agatatctcc ggcgtgaaag atattcctaa cagccacgga aactacgggt tacgaatgcc
    27841 aatgaatacg caagcggctt tcgagcattt cacgttaaca gatcatcaag atataaaaat
    27901 cagtatacgg aaagggggca tccatttaat gctcggagaa aagatgcaag ttaagactta
    27961 ccgccctaac aaaccagaat atgtgtcgat cataacttta aataaagacg atgctactgc
    28021 ttcattcgaa aagacggata taggcagcaa tcccccggga ttggatatta tcgtccccac
    28081 acaggccgcc aataccaaaa acggctatta ttatgtagac agcgtttacg cacacggcat
    28141 gattcctacc tattccctat ttaccggaaa cagcgattgg aaccatgagg atcgctggag
    28201 ccacctaccc gcctaccgtc accgcaacgc cttgattaac ggcaatatct ccataaatac
    28261 aaatatcagc tgtaaagata tctttattgg caatggaaat atccatattt taccaaccgg
    28321 aaatctatcc gcaaataacc ttaccatcta tcctaatgat ggtatcttgg cgtcttcctc
    28381 caccttgcga tcgtctggaa ctattaacat ctccggcaaa ataacaatcg agaagacctt
    28441 cgctcaaaaa ggcaaatggt attttatctc cttccccttc gatgtattcg cttccggcat
    28501 agacccggat ttccaactgg gtgatgacaa aagcgataca aacggtaatt acttttacgt
    28561 acaaacctat aacggagaaa agcgagctaa ttcacaaagc ccttccaaca actgggaagt
    28621 cataccacaa acaataatca atacatccca gcccatcttc aagaagaaca agggatacct
    28681 aatcgctatt gacgcttccg ccgatcgtca gaaccttcgt ttctcctcga aagcaggaga
    28741 tatccctata gatttcggaa aaaacggtca agcctctatt ccggtaagca ttaacaacca
    28801 aagccagaac cagaatcaca acggctggta tctatgcggt aatcctctgc cggctccttt
    28861 atctcttagt caaatagaat caaactcggc cttagacgga tacatttata tatatgacgg
    28921 ctccacctac caaccctacg tgatcggtag cgatttcgcc atccctccat tctccgcttt
    28981 ctttgtcaaa gcgaataaaa gtaccagcct atctgtatat aatacatccg aaccagccaa
    29041 ttataaatta ttatcaacga acgcacccat atctttcccg acatcggaac ctcaagccca
    29101 acaagattcc cctgtttcca atcaagtatt ttcatttccg gaattaagct atcagctaga
    29161 gaacaagact ttattcatta ctaatcttcc atcccccggt aaagtcgaac tgtttactcc
    29221 ggcaggcata ttagtattca cgcaagcggt acaggcaggg aaccctatcc tcccgattcc
    29281 cctcccacaa ggtttatata tcttaattat tcaaacagaa cattatcggg cacagtacaa
    29341 atgcgtttta acctcctaaa gcccgaaaca atcttatatc tttgccctgt ttttagaata
    29401 aaacgaatat gaagaagatc aatatcacaa caattgcctt acttgtttac ttaatcgtaa
    29461 tgagtatcat cggctggccc ggcaataacc cgggtaatag ctataccgaa tatttcctga
    29521 tgatcggcgc tacgctcgtc atcatcatcc ttctacgcta tctgcaagtc aagcgcttga
    29581 gaatgcggga caagtggaat aaagacgacg atcctgccaa gcaataaaaa cacagcctgt
    29641 ttttcttcac agaagaacag gctgaatgaa ctttatttta ttacactagt attaatatta
    29701 ctgctttttc gccttcacag gctacttgaa tgtctcgtaa agactacgca cagtataaat
    29761 tattcgatta taaataagta caatcttaac aggacacaca caccacttgt ttcgcttact
    29821 ttcttaaaat gagttacttt cataattctt acattttatt cactagtact aaaacgtcat
    29881 taaccaatac gcaaaagaca accgacatca tttttgtaat cgtagcctaa tcgtcatatc
    29941 actgaaaggc aatacaatcg tgaacacatt tttaataaca tagacatatc atcgtaatat
    30001 aatcacacgt cctttgcgtt ctgaaaaaat agattaattc taatatattt taaggacaaa
    30061 aggatggaca acagaaatta ctttacgatg gcgattcccg ctcttttgct aggcgtagca
    30121 tacttacagc caatcaatgc ggcaccagcg gaggatctgc caaacgttac tggacgaatg
    30181 acgatcactc aacagacatt cacggtaagt ggcgtagtca ccgatacgaa cggagaacca
    30241 attatcgggg ctaacgtgat tgagaaaggg actacaaatg gagccgtaac cgattttgac
    30301 ggcaaatttt ctctctcgct gcaaaacaag caaagcatat tggtcgttac ttatatcggt
    30361 tataacacca aggagattcc agccgggaat ggttctcccc tcacgatcca attgcaggat
    30421 gacacccaga acctagacga ggttatcgtg gtaggttata gtgtacagaa gaaaaaagac
    30481 cttaccggtg ctgtttccgt actggaggta ggcgacctga aagatacccc ggtatccagt
    30541 gtagatcaaa tgatgcaagg caaattgtcc ggcgtaaacg taatcccgga taatatgccc
    30601 ggcgggggtg tagcggtacg tgtacgcggt ttcagcacga tccgtaacaa tgatccgctt
    30661 tatatcatcg atggcgtgcc agtagagggc ggcatcaatt ttctcaaccc gaatgatatc
    30721 gaaagtatgc aggtattgaa agatgcttct tccgcttcca tctatggcgc acgtgcggca
    30781 aacggcgtgg ttatcatcag tacaaaaaaa gggaaggaag gtactttccg ggtaaaccta
    30841 gacgcttacg tgggtgtaca aacctcggca aaacagatgc gtatgctaaa cgcccaagaa
    30901 tatggcgact tattatggca ggcacagcgt aacgacggga aatcaccagt aagcgacgtg
    30961 tatggctccg gcgagaccgc cgtaattccg gaattccttg acgcagatca ccgtcttccc
    31021 tcgggagacg tggattgggt tgacgagatc atgcaaaaag ccatggtcca gtcctataac
    31081 ctctctctgg cgaaagcaga taaagttagc agccacttgt tctccctagg ctatttcaac
    31141 caagacggtc ttatgaaata tactggtttc gaacgtatat ccggacgttt caacaatgag
    31201 ttcaagctct tcaacgatcg tttgaaaatc ggtgagaacg ccacattatc acatgcgtgg
    31261 ggaacctcgg tcaccaataa cgccgcactg ggaggtatgt tatacaacgc ctataagacc
    31321 gtatccatta cccctgttta cgatctggac gggaatttcg gcagcaaccc gatcgccgac
    31381 atctccaacc cgttaggcga attataccgt aataaggata ataaagatcg taccacccgt
    31441 ctattcggta atctattcgc cgaactgaat atcctagagg gactttattt caagaccaac
    31501 ttcggagcgg attacaaaaa cctgtataaa cgaagcttca aggccaaata caacgaattg
    31561 aacacccagc aacccttgag tacgttgagc acgcaaaacc gttggaactt caattgggta
    31621 ttcacgaaca cgttaaacta tttacggaca ttcgataaac atacgatcgg agccttatta
    31681 ggtatcgaga caaaccgtta tcaagaggaa tacttctccg cctcccgtga aggctttgcc
    31741 tcggatgacg ataacttcca tttcctcgat gcgggcgata gcggctccca gaagaacgca
    31801 ggttctgcct ttacttccaa gatgatgtct tatttcggta aaattgatta taatttcgac
    31861 aaccgctact tattctcagc cacgttccga cgtgacggat cttctaaact tggtaacaat
    31921 aaatggggta atttcccggc tgtctccgca ggctggcgta tcagtagcga accgttttat
    31981 gatattccgg ctatcagcaa catgaaagtc cgcataggtt ggggacaaaa cggcaactct
    32041 gatatcccgg cttattctac gatcgattct tacatgagta atccgaacca ctccaactat
    32101 ccgatcgacg gtagccaaag ttccgtgaca accggataca cccaaacccg ttacggtaac
    32161 gcaaacctga aatgggagac caccacgcaa actaatgtcg ggctggatct aggcttccta
    32221 gataacagcc taaccgttgt gctggattgg tttaacaaag ataccaagga cttattatgg
    32281 gagcgtccct tgatcggtac cgtggggggt acgaaccaaa cggtatggga caatgtcggg
    32341 aaaatgcgta accggggttt cgaagctgag gtcagctaca ataagagcat caataaagat
    32401 ttcgggttca atgtcgcctt caatatgtcc gctatcaaaa acaagatgac tgaattagac
    32461 ggtgatgtct cctatatcgg actgcctacc agcgtgattc actccctcaa cttcgatcaa
    32521 gaggtttctc gttccgccat cggacaacca atcggctctt tctacgctta taaagaagac
    32581 ggtttattcc agagcgaggc ggagatcaaa tcatatacca ataataaagg cgaactactc
    32641 caacccaacg caaaaccggg tgatatcaag ttcgtagacg taaacggaga tggcgtaata
    32701 gacggtaacg accgtgacta tatcggtaac ccgctccccg atgtcacggc aggccttaca
    32761 ttaggagtca acttccataa ttttgacctc agtctattct ttcagggaat gttcggaaac
    32821 gatgtatacg acttgacccg ttatgtgggt gatttctaca atcaatcgca atacaacaaa
    32881 aacagccgtg tcgttaacgc atggacaccg accaacacga atacggatat accccgtgtc
    32941 accatggacg atccgaacaa taacatccgg ccctcgtcct actatgtgca agacgcctct
    33001 ttcgttcgct taaagaacat gaaaatcggt tattccgtac ctcagtccat cctatccaag
    33061 attaagttca atagcttgta tatctatgcg caagcaacca acttattcac gatcaccgga
    33121 tacgacggta tcgatccgga agtgggattg caaagttact ccagtgacta ccgtaaccta
    33181 gatatgggtg tggaccgcgg catctatccg ttatcccgca ccttcacctt tggagtaaac
    33241 gtaagttttt aatcatcaaa caacaacaaa caagaatatg aagaaaatga ttatagcggc
    33301 ctgtgccgta ttcgcattga catcatgcag cgattttctg gaagagacac ctgtaggcga
    33361 actgactccc gaacaagcac aagatcccaa taacatcgag ggattgatta tctccgccta
    33421 ttccatccta gacggccaga tggacgatgc cagctccggc ttgaattcag gatgctccaa
    33481 ctggcaattt ggcgatgtga tctcagacga tacctacaaa ggcggaggtg gtacgggaga
    33541 ccagaacccg attcacttga tggaaatctt ccatatcgac ccgactatcc aagattacaa
    33601 tcggaaatgg ctagccttat acgagggcgt gaaccgctgt aaccaagcga tccgtatcct
    33661 caaaggcagc gattatgata aaaaggagac ccgtatcgcc gagatgcgtt tcctgcgtgc
    33721 ccatttctat ttcaacttaa agatcatcta taaccagatc ccatatttcg acgagagtgt
    33781 cagcgatcct tccgcgttcg cctctatctc gaataaggag tatacatccg atcaattatg
    33841 ggagaagata ctgaatgatt ttaaggccgc ctacgaaggt ctcccggatt cccagccgga
    33901 tgtggcacgt ccatgcaaga tgacggcccg ggcttatatg gctaaagttt acttgttcca
    33961 aggcaaatgg caggaatgcg ctacagcgac ggatgaggtg atcaattccg gcaaatacca
    34021 gctactcccc gacttccgga atatcttctt gccggaaaat gacaactgcc ctgaaatttt
    34081 attttcagtc caagcctcta tcaacgatgg ctccccgaac aactacaacg gaaatccggg
    34141 cgaccgtttg ttacctccgg gaggccctta tcccaactat ggtttccttc gtccttccca
    34201 aaacctagta aacgcttata agaccgactc caacggcttg cctttggaag acggcataga
    34261 cgtttcggaa aatgattatg tagacacccg cctagaccac acggtagccc gccccggaat
    34321 catgttccta gatgtccaac tctatgactg gactcctcgt gaggctacgg tttacggtcc
    34381 gtatagcccg aaaaaacgta ttgtctccaa gaactcaagt tactatttgg ctatctggcc
    34441 atacgtaaac gcattgaatg tttatattat tcgatatgcg gacgtgttat tgtggcgtgc
    34501 cgaagctgct atcgaactag gcgatttggc taccggattg aaatacatca accaagttcg
    34561 cgagcgtgcc atgaacagcc agaccgtaaa aaccgctgac gggacagcgg atgccgccaa
    34621 ataccggatc ggattatatc cgtcattttc cgacaaagag gaggcgatcc gagccttacg
    34681 taccgaacga cgtctggaat tcgccttaga aggtgaacgt ttctttgatc tagtccgttg
    34741 gggaatcgcc tcagacgtga tgaacactta tttcgagcat gagaagacat tccgctctca
    34801 tctccaaaat gcccgtttca tcaaagggac ccacgaatac ggcccgatac cgcaagcggt
    34861 tatagacctt gcgaaaaatg gaatcatcga gcaaaaccca ggatattaat gggaatgctc
    34921 ccattcttct taaaagaaat agctcctatc cgaatattcg agcaggagct atttacattt
    34981 gtctttatat cgtctcttta taacttatcc cttaaaaacc taccggtata ggatgcctcg
    35041 caagccgcta tctcctccgg tgtgccggca caaaccagct gtccgccggc ctttccgcct
    35101 tccggtccta aatcaatcac ataatccgcg catttgatca catccatatt atgctcgata
    35161 attaccacgg agtgaccttt ctcgatcaag gcattgaaag ctttcaacaa agtcttgata
    35221 tcatgaaaat gtaaaccggt tgtaggctcg tcgaaaacga acaaggtagg ttgctgcttc
    35281 tcttggccta agtaataagc cagtttcaca cgttggttct caccaccgga taaagtggag
    35341 gaagtctgtc ccagcttgat atagcccaag cccacgtctt gcagcggttt caagcgtttc
    35401 acgatcttct tttcttggga gccggaacct ttctcgaaga actcgatcgc ttgattcacg
    35461 gtcatttcca acacatcgta tatgttagcg ccttgatact ctacatccaa tacatcctgc
    35521 ttgaagcgtt tgccgtggca agcctcgcat tccaaggtga tatccgccat aaactgcatc
    35581 tctaccgtga ttttgccctc gcccttacat tcctcgcagc gacctccttc tttattaaag
    35641 gaaaaataag cggcgttata tcccatctgc ttcgctagag gctgctcgcc gaatagttta
    35701 cgaatctcat cgtaagcgcc gatatacgtc acagggttcg agcgagaact ctttccgatc
    35761 gagttctggt ctacaaactc aatcgcctga atcatattca aatctccact gataccggag
    35821 caatctacgg tcaggcgggc ggcatcatcc aaatggcgtt tcacgccctc gtagaaaata
    35881 tcacgaacca aggaactttt acccgaaccg ctcacgccgg taaccaccgt catcacgttc
    35941 aaaggaaact tcacgtccac gccctttaag ttattcttcc gagcccctgt cacttctata
    36001 taattattcc acggacggcg ataaggcggg atctcgatct gatcctctcc cgtcaaataa
    36061 cgtaccgtat ggctatcggt acatttccgg aggttattca catcgccttg ataaacaacc
    36121 tcacccccca aacgccccgc tttcggaccg atatcgatga tataatccgc cgcacggata
    36181 atctcctcat catgctccac cacgaccacg gtattcccca aggcttgcaa ctgtcgcaat
    36241 accttgatca gcaaatccgt atcccgggaa tgcagaccga tactcggctc atccaaaata
    36301 tacaacgaac ccaccaagct actacccaac gaggtagcca gattgatacg ttggctctct
    36361 cctccggata aagaggccga gaggcgatct aaagccagat aacccaaccc cacatccaac
    36421 aggaattgca agcgattatt gatttccgtg agcaaacgtt tagcgatcgc cgcatccgtc
    36481 tcgtccagtt ccagttgatc aaagaaagcc tttgcctccg aaaccggcat cgtcaccagc
    36541 tcggcgatat tcttaccgcc cacttgcaca tacagcgctt ccggtctcaa gcggctcccc
    36601 ttacaaaccg ggcaagtcgt ctttccccga tagcgggctt gcatcacccg gtattgtatc
    36661 ttataaagat tctcttccac gaacttaaag aaatcgtcga taccgtgtaa gcctctcgcc
    36721 ccatgccaca acagatcctt ctctttctgt gtcaggtcgt aatacggacg gtggatcggg
    36781 aagttatatt tctcgctctt cacgataaag tctttcagcc attcccccat cacctcacct
    36841 ttccagcaaa ccacggctcc ttggtagaca gacaaacttt tatcgggcac caccagattc
    36901 tcatcgatgc ccagcacctt accgaacccc tcacaagtcg gacaagcgcc caacggatta
    36961 ttaaagctaa acatcatatc ggtaggctcc tcgaatatca tgccatccgc ctcaaacttc
    37021 ttcgagaatt ccttcacgac taccccttcc tccgtataaa tacggatcaa acaggtacca
    37081 tggccctcaa agaaagcggt ctcggccgaa tccgccaaac ggcttttcaa ggtcttatcg
    37141 tccgataccg tcaggcggtc caccaacaac tcgatcgggt aagacagtaa ctcctcgctg
    37201 gccagtacct ccgagatacg atataccgta tcattcaccg acagacgggc atatccttct
    37261 ttccgcaaga tctccagctg ttccttcata tcccggcctt ccggcaagac aaccggggcg
    37321 aatacggcaa aacgagtccc ctcggggtat cgcatgacct ccttgacaat atcgctcacc
    37381 tgatgttttt tcacctcggt gccggaaacc ggcgatatcg tcttcccgac gcgagcatat
    37441 aacaagcgta aatactcata aatctcggta gatgtaccga ccgtggaacg cggattacgg
    37501 gtattcacct tctgctcgat agcgatagcc ggcggtattc ccttaatata gtcgcattcc
    37561 ggcttactca tcctccccaa gaactggcgg gcgtaagcgg ataaactctc tacataccga
    37621 cgctgtccct ccgcataaag ggtatcgaac gccaacgatg attttccact ccccgacagc
    37681 ccggttatca ccaccagctt gtccctcgga atctctacat ctatattttt caagttgttg
    37741 acacgtgccc ccttgatgaa aatcgaattg ctctcagaca tattaccttt atctttttct
    37801 ttaacgcaaa gatagccaaa actaaccgat tctgccttat cttcatcgaa ctaattcaca
    37861 cagttagaca gggtgtgcct cgtctctact gccaagtaaa taaaataaca agggtgaaat
    37921 atttcatatt tacagggaat cttctacatt tgttgaaaat ttcatagaca aacacagcaa
    37981 ggcacccatg tatattaaat attttcgctt cttagtagcg attctctttt gtgcgataac
    38041 ctcatgttct acggttcgcg agaagcctcg tccggctacg agtacgggca aggaggccaa
    38101 gcgagagttt aggggagcat ggatacagac cgcttttcaa ggcgaataca aggatatgac
    38161 tcccgcccgg atgaaaaaag acttcatccg caagcttaat tacctgcaag catgcggcat
    38221 caacgccatc atctttcagg tgcgccccga ggcggacgct ttctataaat ccgatatcga
    38281 gccgtggagc cgcttcttca ccggagagca aggcgtagcc ccggcaggtg agttcgaccc
    38341 gatggccttc ctgatccaag aatgccataa acggaacatg gagtttcacg cttggttgaa
    38401 tccttaccgg gcgagcacgg cgggaaacac ccgtttcgcc gattcccaca tctatcataa
    38461 acatcccgaa tggtttgtca cttataataa acaaatcctt ttcgacccgg gattgccgga
    38521 aagccgtcag tttatctgcc gggtagtgcg tgatatcgtc ggccgttacg acgtggacgc
    38581 tatccatatg gacgattatt tctatcccta tcccgtagcg ggtatgcctt tcccggatga
    38641 taacagcttc cgcaaatacg gcttgcgaaa aggatacagc gaggcgcaaa ggaacgattg
    38701 gcgccgggag aacgtgaata ccctgatccg ggaattgaaa cgtaccatcc tgctcaccaa
    38761 gccttgggta cgcttcggta tcagtccctt cggcatctac cgcaacaaga aaagtaccgc
    38821 ggacggatcg ggtagcaata ccaacggcct gcaaaactac gacgacctct acgccgatat
    38881 cacctattgg gtacagcaag gttggatcga ttataacatc ccccagatct attgggagat
    38941 cggacacccg gcggcggatt acatcacgct tatcaaatgg tgggacaaaa acgccaacgg
    39001 aggtcattta tatatcgggc aagacgtggc ccgcaccatg aaagcggacc aattaacccg
    39061 caagatgcgt tatgagcgtg ccttgcctca cgtgagcggc aattgtttct ggcccgccaa
    39121 cgagattcta tggaacaaca agggcgtagc cgacagcctg aaacggaact accaccgtta
    39181 cccggccctt atcccagcct atacccatat gcataaccgt ccgccaaaag acgtaagcaa
    39241 gctaaagacc gaatggacgc ccaagggctt cctcttgcac tggcaagcgg agcaaagccc
    39301 cacgaatccg gagctagcct cttatttcgt ggtctatcgc tttaacgaca aggagccgat
    39361 agacacgagc gatccctcga agatcgtggc tatcacccgg gaaaccggct acttgatgcc
    39421 ttacgagaaa ggaaaggtaa aataccgcta tgtagtgacc gccgtagatc gctttcacaa
    39481 cgagagcgag ggcaagacaa agaaagtaaa attataaaga caccaattat gttaaccgac
    39541 catcgctgca ccaaatatac cgactgttcc tcttgtggtt tctaccagag ggatatattc
    39601 aagtatcgtc tttatccgaa agggtacgtg atccctcaga caagatgcat gcagaacatg
    39661 gtattcttcc tgatcaaggg agagatctgg ctgaacagcg aggagcaccc ggacactacg
    39721 ttccggggcg gacagttcgt attgcaaccg atcggctcga aagtggagtg caagatactc
    39781 gactacaccg aatgtatcat ctatctcttc gagcgtccgc aaaacatatg cgacaaccgt
    39841 ttcaataaag gcatctccat cgtggagaac gaacgccagc agcccatcgt catgacgatg
    39901 gtcccgccga tacaactctt catcgagggc atgaagctct acctcaacga tgatttaaga
    39961 tgctccggac tgatgcaagc caaacgatcg gagatggtct acttgttgaa ctgctactac
    40021 cccatcaagg agctagccgc cttttacgcc ccgatttacc ggtatagcca cagtttccag
    40081 tatttcgtga tgcagaacta ccaaaaggcg aaagacgtgg agaccttcgc tcaattggga
    40141 ggctacagtg tacccacctt ccgccgtatc ttcaaggata cgttcggaga gcccgcttat
    40201 caatggatgc tgaagcgcaa atgccaagac atccacaacg accttatcat gaccgagctt
    40261 tccatatccg agatttgtta caagtatggt tttgaatcgc tttctaactt ctcgcacttc
    40321 tgcagggcta attgcggcca atctccccgc tctattcgtt ctctaaaaga tgaaaataca
    40381 taatattcaa tgattttttt aaaacttctc aacttttgca actctttgga caaaaataac
    40441 aattctcccc tttagcatta cctatacatt tgcgtccaga aggtcaatca taattgattt
    40501 tcaaagaaaa ataaaatgta taggtacaat aagacaagta ttatcttaaa gatcacgatc
    40561 gccattctat ttattacgag tttagtgata gaatgcagtt gcgagagatc tgacgaaccg
    40621 aaaaaagaga gtaccggttt catcacctac acccttcgtt gggatagcgt gatacccggc
    40681 tttccggctc ccgagaaact tcgatattgt atttaccctt cggagggagg gcctatgata
    40741 cagacggatg gggacgcaaa tagcatgatg ttgttcttac cgccggccac ctataaaata
    40801 ctggttttta attacgacgc gaagaatatc gactttcgta atatgtcaag gttcgacgaa
    40861 gcggaggctt atatcctcca gacgaaggcc accggacagg catcgcaagg cataaccccg
    40921 ttgtatgggt ttgtcgtcga ttcattggag atcacaccgg ggcaagacaa gtcgggcact
    40981 ttggtactga ctccgttggt ccgccacgta acctttacgg tacaggtaga caaaccggag
    41041 gagataaaga cttgcaaagg ttcattatcg ggcgtatcca cctcattaaa cttgagtaaa
    41101 cgcaaggtag tgaccgaggc atccacaaat gtagagttcg atatggaaac ctccgataaa
    41161 ggagtaaacg gcgatctgat catattaggt accgccctcc ctaaggaaga agaacaaaaa
    41221 cctgtcacga atcaagtgac aatagatttt accctaagcg acggtagcat ggtttccgct
    41281 accgccgact tagaggacaa attaaatgaa atagacactc ctcatgtcaa cgtgactata
    41341 aatgccacgg ttgagaagag cccgaaattc acgatccgcc tcacgaactg ggaagtaggt
    41401 cccggcgaag agaccacaat cgaataagat taaaatgata tacaaatagt aacaacttaa
    41461 attagggtaa aatgaaaaag ttaatgatta gtatgttggc catggcagcc atggttagct
    41521 gtacaaatga gattgagaat ccggatcaac cacaagtgaa ccagaatgaa cctactccta
    41581 ttgaatttgg gagttcaata ttgggggtac agacaaaagc tgcaccagga gaaacagctg
    41641 aagcttttga cgtaggtgag ataatgggga taacaatgta tttaggagaa gtaccgacag
    41701 gagcaagttt aggtacgcca agtaaagata atgtatcttt tactgttggc tcagataata
    41761 aactttccga aacagctact gaaaataaaa cgatgttttg gaaacgtggt tcaaaacatc
    41821 aattttatgc atattatcca agaatagctg acgatactaa tgcaaattac aaaaggacag
    41881 ctgcttctgg tagtaatgca gaaaagatca ccgttactgt tccgactact ggagaaacaa
    41941 cagacctatt gatgggaaag cttgaactaa ctagtgagta tgaaggtact gcaccttctc
    42001 ctgctaacat tggttttaaa catatgcttt caaaaatcaa atttgtattc aaaaaagacg
    42061 catcttacac tggagaggct aagttaacga atatatcagt aagcctagat aaaggctcaa
    42121 aagtttttga tatggtagcc caaacaggag atgcgacaag tgcaagccca gtcacaataa
    42181 ctaaagcaag cacatataca attattgaaa atgcagatgg agatatttat acagattggt
    42241 ctcctattgt tatcccagaa gcctcaataa caaatttgtc attgacgatt gacggtcaaa
    42301 ctctttctac tacttctttt ggttcactaa gcttcaagga aagtaaaatg actactttga
    42361 caattacatt aacaagttct aatattgaat taacatcatc aattacagct tgggcagatg
    42421 gcggtacaaa cggcaatgct acagtaaaat aataaaactt atagcgaaag aggcttgaac
    42481 ctctttcgct aaaaaacatt tatataatga gaactattta ttcatacatt gtatacatca
    42541 ttttattatt acaactgaat agttgtaata atgaaggatt aatgtatgaa tatgaacatt
    42601 ctacacctat caaattctca tcatcatgta taaatgtatc cacaaaaagc caaggaatca
    42661 tagagaataa caaattacct aaaggatcta atatcagcat attctcaata caacatccag
    42721 aaaacacgac aataaatcta tgggaaccaa ttttatttga caatattaaa ggtatttcta
    42781 atttcaatgg tgatattgaa tataataata catattattt cccagataaa gaacaacttg
    42841 acttttttgc aatctatcct tttctatcat ttcctacaat aggttctgat tatggaaata
    42901 cccaatatac caccgtcacc ctcaaagaca acaccgtcga tcaatacgac ctcatgtacg
    42961 cctctttact gaatcagtca aagaagtcct ccgtattagt atttgagttc caccacttac
    43021 ttacccaaat aacaataaac atcataaaaa atacaggagt cactatagac ctccctctaa
    43081 ccaaagtaca aattgtcgcc ccacaaagcg ccaccctaga tatatggcac ggtcaattaa
    43141 gcgacatcgc aggacaaaca acctatactt tagacaccaa cacgacatta agcaacggag
    43201 ataattcaat ccccggccaa ttcctcctgt tcccccaaaa agcgaacgaa atgatattaa
    43261 ctttcggaaa cgatgaaagc aacgtgttcc acgtcgccct ttccgatgaa ccgcggactt
    43321 gggaagccgg ggttaattat caatacgata taacgatcaa ccggaatata ccggaaataa
    43381 cctctcccga agttcccgta gatgataacg ctacaccgaa cgaagaggta aacaacggag
    43441 gcgagatccc ggagactcct acggactcta ccgctaccgc ctcccaaacc aaggcatcgg
    43501 gcccaaaccc gtaccatatc catctatcaa tcgactaaat caaacgaaaa gatataacac
    43561 aaaatatgcg atacacaaaa caactgatca ccgtatccct ccttatggga ctctcgctaa
    43621 atagctgcac taacgatgat aattccgtgc cttcccaaca gacacccacc gttatccttt
    43681 tcagcgcctc cccctacagg ttggaatcga aagcgataca taccgagtct accatgccga
    43741 ccgacctgcc gattgggata tacggatggg gccataagct aggccaaacc gcccccctca
    43801 ccccacgtcc cgacctaacc aaccaagcct ataccacgac agacggtacg gcctatacct
    43861 ccgatatgga cgctcatttc ccggtagcct ccgatacggt catcgatttc tacgcttact
    43921 atccgtatca agcctcgctg agtaattccg aagctagcta cgacctaaaa gaccagatcg
    43981 atatcatgta tgctaccccg atcctaaaca agggaaagat ggacgtagag accgacacca
    44041 acagctcaac cgccaccgcc accgtcgccc tcaccttcaa ccaccaatta tccgccatca
    44101 cgatcgtcat aaagaaagcc gatgatatca aggaacccct aatcttgcaa aaagtggagt
    44161 tagtaaatta cccgtcatcc atccacatga atatccagac cggccggtta accgcctcga
    44221 atacggtggc ggactatcca attccgctcg ccgcaccgat taccatcact cccgccgagg
    44281 ctaccgtatc gacaaactac ctgctctggc ccggcgaggc tcccacgttc cgtttctcca
    44341 tcagcgacca tacctacgag gttcatccct cccaagcatt catcgccggc aagaagcaga
    44401 aatatacctt caccatacaa gccgaagaca tcaacgtagg tgcctccatc aatccttgga
    44461 cagaaggccc ggaaggttct ggtgagattg gtatttaaga acgtacgtat ttagcgccct
    44521 atggcgaaaa atacattctg ttagcgaaac aggtgttatt ctgttttttt gagcaatata
    44581 agccatatat cgtgacatcc ccttctcgca agaaccacaa aacaacgaga aggagatagc
    44641 cattagtgcc ctttttctcc tcggaagccc cccttttcac acacaatagg tcgcgaaagc
    44701 caacgcgaaa ggccgcgtta ggcgacacat atggtcacgt tgggcatcgt aagcagctaa
    44761 gaatagggtt ataacctaat gagaaaggcg ttataacctt attataaccc tatcgtaacc
    44821 ttatggaata gcccaaacac ccggcaaacc atgagttacg atgaattaat ttcgctagaa
    44881 taaaaggcca ttttccaaca tctgtctgtc tactaaacaa ttgctatttt tttcttgcgt
    44941 atttggaagc gagacgtaca tccgcccgaa ataatcgact ctcacggact tccgtttaca
    45001 ttttgtcaaa atgtcaatct gcgaggaaac ttctccccac atagcatacg gatatcaatt
    45061 attcttccta tatttgcgat aatccctcat atctaagcgt aggtcactga aggaggacat
    45121 aagttaacga agagcgttta aagatattat cccgtattga aatctggaca atttcatatc
    45181 catggataat agacaataaa cgctcacgtc ggtggtatat ttaccagtaa ttgctctgga
    45241 cgatataaca gcatggcgtg ggctattgtt tattacatgg atagggccgt ccagagcctc
    45301 aatacggtaa tatcaatagt ttccacgctt ctgtattttt agcccggcaa ccgatggaga
    45361 caggttgccc ttatccatta aatgaagacg atcctcctgt tacccgtctt gtcgctatgg
    45421 ctcctgcttg ccacgcaagc ccatgcccaa gtctatcacc tacatttatc cgacaacact
    45481 tgccggataa cagaatgcgt tgatactcca caaggcatca agcccttggg tcagacatgg
    45541 aaaggaaaca ccttccatga tcgtttcacg ctagatttcg atcgcgctat cttcacgtgg
    45601 gaaaaggaag gaaaagagac gtatgccaac aagatcatca accacactgc caaatacgct
    45661 caccactcat tcaccacgga gcagattacc gccaacctca ccatcaacag ccatcgagcc
    45721 gtccttcaac ttatccactt tcagaatggc caatggatac aagtcactta tttttgcgag
    45781 atagggaatt aacggctcat gcgaacatct acaacatcta ccacttatac ttgatatttg
    45841 tactttttat ttgtgagtga aaattccagc cttaaaaaag gaggccttaa agtttacgat
    45901 aaacatcttc aaaaggtact ctgcaacgtt ctccccaaat gcctttattt ccatcccgta
    45961 tcccacaagg aatagccatg tttatttcag caccatgagg tagtttcaat gtccttttta
    46021 gccgacggct gtccagccct tctaaggggc acgtgtcata gccttcgttt gccatcgcaa
    46081 tcataaacgt ttgtgcggca agcgcacagg atttatgggc tgtcacacgt atgtcattct
    46141 cggaaacttc aagcatcata ggacggaaaa tactgattat attagccaac aatttcctaa
    46201 gcaatccgag aataccgaag aaccgggcat aaacaaaggg catcaatata ccgtaatata
    46261 tttcccgatc cttaatacgt ttggcctgac gttctttagg actgtaatga cgaatgttct
    46321 cccgttcaaa attgagtacg aatcgcgcat gtttcttgta ccagtcacgc cgaaccacaa
    46381 aaatgacaat ttgtgaagcg gtagaagccg ctttctgacc aaggcagtcc cttgaaattt
    46441 ttgccaataa ttcaggttct gtaatatggt aaaattccca taattgcata tcagaactgt
    46501 taggagccaa tgtagccagt tccaaacaat gttttacctt ttccgtatct attggttttt
    46561 ctttatcata cacccgtaca gaacgacgat gatgaaggac ttcatctaaa ttcataatga
    46621 tactgatttg aattaaacat ttattcccag ctgattactt cagccattta ttattgtgct
    46681 ttatttaatt gccgcataac gaccttcgcc atttctttag aactgaacgg gtcctgccca
    46741 gtaatcagat tattatctac aactactttt gaagtcatag gtatcaatgc tttttcataa
    46801 tccgctcctc tctctttcaa caacgcttca agatcaaaag gtacttcttc ttttcttctg
    46861 gcaagacttt cctcaaacca actgaatccc gtcagctttt tgcctttaat catatattcg
    46921 ccattggata gtttggcatt caacaaccca ctgaccccgt ggcagatggc cgacactatc
    46981 ctcccacttt catcctgttt ccttacgata gtctttaaag cttcattgcc aggaaagtca
    47041 tacatcgcac cgtgtccgcc ggctaaatag acacaatcaa actgttgttc caacaggtta
    47101 tccaaactgt ttgcatgatc caacagcttt ttgaattctg gcttttccca atacttttcg
    47161 gacatttcat ccaaaaaaat tggttttaaa ctttcgggat caatgggagt ataacctcct
    47221 ttcggattgg ctaccgttat gtcatagccg ctttcttttg cactatgata gatatgagta
    47281 aactcactaa gccataatcc ggtcgcgagt ttcccattgg caaaagtccc tgtgctagta
    47341 actattatta aaatcttcat gataatcaaa ttattgattc atattcttta aaagaaaaca
    47401 tacacatgga tagattgttt ttcagaatat ggaatcttta acataatccg aaaatatgaa
    47461 aacctgcaaa tcctttcaaa tgctatctct atccaccagc attcgataag gagaaattac
    47521 cgatcccttt cctattacct ccgggaggaa gcaatttgat gaatattgtt tccatgatgc
    47581 ccaagttgaa agaagaatta agaactattt tcaacgacta tggcttgaaa tatgtcttcg
    47641 ataccaatag ccaggagatt aaagtaatga aagaaaagaa accgggagag atatttttaa
    47701 ttccatttca ttccatagcc gataccctgc agcgtatgat tttctacaaa gcggctattg
    47761 aaagtaacag tgagtccgca ttagtttttg aagaaccgga agcccactca taccctcctt
    47821 tcatatcaaa ggtaacgcag gatattatcc aatcggacag aaaccagttt tttataacga
    47881 cacacagtcc ttatgtggtt aacgactttc tggaattacc gagtgacgaa cttgccattt
    47941 acctagttga cttcaagaat ggggaaactt tcgtgaaaag agccattgac acagaagtac
    48001 aagaaatgta cgaatatggc atcgacctat ttttcaacac tgaaacatag cgaaagatac
    48061 agaacacatt gcaggcacaa gcccataccc aagtctacca cctacgctta ttcgacagta
    48121 cttgcaggat aacggaatgc gttaaaaact attttacgga atgtccaaat gttctgtcaa
    48181 tacgtttacg aatgttcgta atggcgcacc ttcataatta tccaactccc caaccaagat
    48241 cagagcggcg ttcatccatg ggtggtatgg aatggatagt tcatagggga tttcccggat
    48301 cagttccggg gtgttcttga ttaccgtata agtatcgcca tcggcggctt tcttgccttc
    48361 gaaaactaag gtacggtcgt acattttttg cttgtttgcc ccgtttagta ctaccggggc
    48421 catgactacg gaatctctgt cgctacgcaa catcggcatc aaggacaggg tttgatatcg
    48481 tcccacggag agtccgcaga cactgatcgt taggtctaga cgcaaggagt tgccctcccg
    48541 ctcgatgcgg ttttgcttca cggagacttg cccccggtaa gattgtatag gtacctgcgc
    48601 tcctgccgga agaacaaggc cgatcacaag caagcatata taaatgaatg tcttcataga
    48661 tttatctctt tatttgatga tgtaaacgat actgataccc gcctttgtta atccccaata
    48721 ctcgttgcgg aacttgccga taggcgcatc tcctctagga aaagcgtact tatcatattc
    48781 gaaatgcaag tatccgaaac ccgccgtgaa ctccacgttc caacggggcg acacgtataa
    48841 ctgataacca taagagatac cgccgccata agcgttaccg ttataactat tctttttctc
    48901 catcccatac aggagcttca aaccggcgaa atcgtaatcc atatactggg catgaacccc
    48961 gaagaaatgt ccgttgaaac gctcgtgtat ccagtagcgc gcctctggtt gtatcatcca
    49021 atgcttaaag gacttatcgc tcgagaatgt ccaaccgtta taataccccg atgcctcaac
    49081 cgaccaatgc ttgttgaacg cgacctccgc ccctacgttc ggcgtagtga tcgcatcata
    49141 aagcacattg gtcttcacgg ccacgacctg tccttgaata tccataaagg ttgacaaaag
    49201 aaatactaac agtaaatata gtttattcat atctcccggt tcattaggtt tgtttattta
    49261 agagacaaaa ccgtacaaat ataaatatta tttatcagtt catttgtacg ttaacttata
    49321 taatatccat gatttcaaat gaaaaacgtt atctttgtaa aataaatcca gaatatgact
    49381 catgaaggct aaatatatcg tgattttttt cctgtcactc ctttcgtttg tcgcttgcga
    49441 taaagaggag gtcgttatcc ctactaccgc ccctcgtacg gttcttatct atttcgcggg
    49501 ggataatagc ttgagtggat acgtgagcca aaacctgagg gcgataaagg aagggattga
    49561 gcgagatgga ttgaacaacg gcaatttgtt gatctatacg gataagcaga acgaggctcc
    49621 ccagcttttt caattaaagc tggaagcgga taccatccgg cagatcgtgc tcgagaccta
    49681 cgactcgaac cagaactcgg cctctaccga gacgctgacg caaataatcg acaaggtaca
    49741 aaaggaatat ccggcggata gttacgggtt ggtgctgtgg agtcacggaa cgggatggct
    49801 accttcggat atctatagct atctgcgttc tttcgggcag gatgggaaga ataatttcat
    49861 ggagatcaat gatttggcct ccgctttatc gaagtatcat tttgatttta ttttgttcga
    49921 cgcttgctat atgtcgtgtg ccgaggtagc ttacgctttc cggggatgtg cggattatat
    49981 tatcggctcg ccaacggaga tattggcgaa cggcttccct tatcaatcga taatggggga
    50041 tatgttcaag aaagaagctg atgtggtggg gatagcgaca aagttttata cgtattatca
    50101 aagtgaggca ggaacaatct cggtcatgaa aagcgatgag ttggatgaat tggccgctac
    50161 ttgccgtacc ctattccatg ataagacgga aagtgatctt ttcgccgtac ccgttagcga
    50221 attgcagatc atggagtatt tgacgccgaa ttatcatgcc ttatatgatt ttgatgatta
    50281 cgtgagccgt ctggccacgg aagagcaata taacgcattc aagcggagca tggaaaaggc
    50341 ggttatttac aaggctacta cacccaaggc ggtttacgct tatccgtatc cgtatggaag
    50401 ctatctgccg gtcaataaat atagcggcct atctatctat gtcccccaag aagccttgcc
    50461 caaactaaat gagtggtaca aggatcttga gtggtataaa gatgtatatc aatgattaaa
    50521 actcatctct tagccagcgt ttaccacgag gggtatacag gaatatcaag aaacctgccg
    50581 ccattataga aataaccgta aagaatactg ctaataacat atttctctat tttaataatt
    50641 tatacccaat caaagcaaat actgtagcga taaacgttcc agtaaataaa gaataccaga
    50701 atataggagg ccacagcatg atatctctcg tatcctccca gcggtttaat aatgcgcttc
    50761 ctactcccaa tacaagagcg gcaaaagtta attttgacaa atcgaagaaa tactttgaag
    50821 tattttctct tctgttcttc attaaatcct gagccgcttt tcttttttca atgttaccgt
    50881 tatagttact catagcaaaa atactaatat tatttcacaa atgaacttat ttcactaaaa
    50941 acacttcctt atatcgtttt acctgtcctt gaggatgaac aagttccgca tagaaaatat
    51001 aaacgccggt tctcaccttg gaaccattca ccgcaaggcc gttccaagcc aattcacctt
    51061 ctatccctaa taagtcatga tttaccacct cactgatacg ccttccggag atatcaaata
    51121 tccaggccct acaggtatag ccggattcat caagatggta ggagatcgta tattccttcg
    51181 ttgcctcaga ataaacggga gactctatgc ccgtgacctc gccttcatct tgctttccat
    51241 attgggaatt ccgatagccg ggcgtaccgt atcccgccgt agccgaagcc gaagtccaat
    51301 tcatctcatc ctgcgtatcg ctatcaggat taatccgctc caaggcaatc cccttctcat
    51361 ttttcacgga tggggcatgc catttagagg aataacgaat ctcatcgatc ataacctcat
    51421 cttccgtacg aaacaggact agcgtagcgg aggtatttgc caagaccgga agttttaatt
    51481 catgcaaagc atccggcgaa gatatcagat aaaaatcgct cactccttct atacttttag
    51541 tcagcaacgc ataatcttgt ggttctaccg gagagactat agaagataaa ggataatgcg
    51601 tactcaatgt accatcggat ttacgggtag caacagacag tccagccaaa ggcaatgtcc
    51661 ggtccgaacg attataaagc tcgatatact cactcccttc cgggtaagga ttcgacaaca
    51721 actcattaaa aatgatctca ttgggtaaga ctataatgtc cgtggggata cccggtttat
    51781 ggggagtgtc cggacgatcc ggatcttctg gttcatcgtc aggagaagag tttgcggaac
    51841 ccggcgtgcc tcctcgctca tccgttgata aataaaaacc ggtttcagaa cgttcccaag
    51901 cgataccggc tttcgctttc tcataggcaa tccggtcgat ctccttaccg gaaggatcta
    51961 ataacgcaag ctccttcccc gtgttcgcca aagacgccgg gaatttatcc aagggcagat
    52021 ccagccccgc atcatcaata tgtatatccc taccggaccg ataaagcacg acatatccat
    52081 ccgcatccaa aagcaaagct gtcaataccg ttggcttact accatataag aatgaccaac
    52141 catttaactc tatagcctta tccgtcgtat tataaagttc cacatactcc gtttccggaa
    52201 aagccttttg tcctttcgga tcagccatca cctcattaat acggatacta ccggcgggga
    52261 aagaaggagt atccggcact tccggttcct ccggaacgtc gggctcttct tcatattcta
    52321 accgaatctc ggtagaactc tccggaatct tatttccctc aagatccatt aaccccgagc
    52381 acaacaaatc ataacccata ccaaccttca actccttatc aaagctgata ttcacatgga
    52441 tccgcatatc atccgcatag gtcatacgag aggcattacc gatacccgat atagagaata
    52501 tcgcctcacg gatatccacc ggaagattat attgtaattg gaaaacagac tcggtgatcg
    52561 gttggatagc aagaagccgc ggaagaacca acggctcatc gggctcatcg ggctcattgg
    52621 gttcttctgg ctcttcggga gtatccggct tctctggttc gatcgagata ttatcggata
    52681 taatgatgta gttacacgca aaatcattta ctcgcgtttt agaatagcgg cattcaaaac
    52741 gtagttgtcc ccctttacat gaagaagaaa cttcagactc acaactccct atcaagacaa
    52801 acctaccctt ctctagcaca tataagttcc atatcttatg attttctaaa gtaagtttca
    52861 ctttcaaatc cacggctccc aacaagacat cgagcgcttt ctctattaag atctttggat
    52921 tcttctccgt tgcggtatgt ttccgaaaag ttatcgtttt cttattactg ccgatttgga
    52981 cataataatc gttttttaat ccaagcatcc tctgatcatc taaataaaca tgtagccgga
    53041 tatggttttg atcgcttggt ttgaaatcca tccgaatctc aaattcccat tccattgtag
    53101 cggaataaac gagaggagtt tctatggaaa cacttttccg ggtaggatcc gcacgtgaga
    53161 ccagccatcc gttctcaatc acaaagcaat ctaaatcacc cgtccaaggg ttatccgatg
    53221 taatctccgg tccattaaac ggttctttta actggggata agcgcaaagc ggaagtaaaa
    53281 acgcaagaat taataataat tgtttcatag ctatatcgtt ttagttataa atttctctat
    53341 ctttgcaccc taataagtta caactgtaaa taatagggcg caaaaggcaa aaatatgaaa
    53401 gccctttaca gacagcaaag ttataactat tttacattat tcaaattaaa tcagtgctca
    53461 aaatgaaagt agcaattgtt ggtgtaagtg gagccgtagg acaggagttc ctgcgtgtac
    53521 tcgaccagag aaacttcccg atggatgagc tggtactttt tggctcatct cgtagtgccg
    53581 gacgtgttta taccttccgt ggtaaacagt ataccgttaa ggaactgaag cataacgacg
    53641 actttaaggg aatcgatgtt gcttttgttt cagccggagg tggtacttcc aaggaatttg
    53701 agaagacgat cacgaaacat ggtacggtga tgatcgataa ctccagcgcg ttccgtatgg
    53761 acgaggatgt tccattggtc gtaccggaag taaacccgga ggatgccttg aatcgtcctc
    53821 gtggtgtgat cgctaacccg aattgtacca cgatccagat ggttgtagcg ttgaaggcga
    53881 tcgagaactt atctcatatc aagcgtgttc acgtatctac ttatcaagct gccagtggag
    53941 caggcgctac cgctatggct gagttggtaa aacaatatga gcaattatta aagggcgagg
    54001 agcctacagt ggagaaattc gcttatcaat tggcatataa cgtaatccct cacgtagacg
    54061 tattcacgga aaatggctat acgaaagagg agatgaagat gtataacgag acccgtaaga
    54121 tcatgcactc ggatatcgag gtgagcgcta cttgtgttcg cgtaccggtt atgcgcgcgc
    54181 atagcgaatc tacttgggta gagacagagc gtccgatcag cgtggaagag gctcgcaagg
    54241 ctttcgccga ggctgagggt gtggtattgc aggatgaacc ggcaaacaag gattatccga
    54301 tgccgttgtt cgtagcggat cacgatccgg tttacgtagg ccgtatccgt aaggatatca
    54361 gcaacccgaa tggtttgaca ttctggaccg tgagcgacca gatcaagaaa ggtgccgctt
    54421 tgaacgccgt gcagatcgcc gaatacttgc taaaggtggg taatatcaag taacagacaa
    54481 ctttgtaaat tctatatacg tggaagcggg atcaagagaa cactcttatc ccgctttttt
    54541 attcttagcg taattcctcc atgccttctc aaaacgtata aatcaatacg cccaataccc
    54601 gatggttggt tatcgaatgt gtgtcatgaa tccgtccacc atcctgcaaa tccacattac
    54661 cataccatgc aatggaagga ctgtattcaa cacccagttt ccagtgcggg aggttatatg
    54721 aaagttgtag gttggtcgta aatacctgat ctacatccag acctacgcca taggtcttgc
    54781 ctaccagtgc ctcgttcgct cccaagttct tcaaatagcc taagaacaaa cccggtttcc
    54841 atttcttacc atacacgata ttcaaccaag aagtggagaa gagatacggc gaatattcct
    54901 gttcgccggt acgtgagtcg atagaggtga cgccgtaacc acccaacata caagtctgcg
    54961 tcaagttaga agccagcaat gttttcgcca tcaccaacca attagcgtcc tgatatttca
    55021 cgtgcgcctc gccggatacg gaagtaaccc gctcgctgac tttataaatc ttgccatcca
    55081 cctcgttctg cgttctcggc accaacgaca agatttccat accggctcct acctgccaac
    55141 cgggtttctt ataatccacc ccgagataga cttccggtac gcaactattc ttgatatatt
    55201 cctcactctt tccattcggt ccggccgata gatattgcaa ctgccataga accgacccgg
    55261 tcaattgcca cccattgtcc gtataacgat aacgaatttg cgggctgcgg ttaaagggct
    55321 ggaacggggc gccggtagaa agattcaaca tctgtggaaa gacctcgcca aatagcggat
    55381 gccatgtctg tccgatcaag acagcggact tgccccaatc cagattcaca taggcatgac
    55441 ggatacggag caccgcccaa ttgctacccg aaccccggaa atcggcctcc agtttcaagg
    55501 aagtcttggc cgaaccaacc ttcggtcctt gtacatcgat tcccaaacgg gagtaaagca
    55561 ggtaaaaact accgttcgga ctagcgttca agtccttgcc atccgcatcc aacgccacgt
    55621 ccttcggata taggtggaac aaaccatcca cgatctcggc gttcgcacgg gaattataga
    55681 acaagtctcc acgtacctgt ccgtaaaatt tgtaagagaa gtttttcttt tgcgcctgta
    55741 cgcataccgc catacatagg ccgatcaaaa gaagcaagtt gcgtttcatt tccattccgg
    55801 tcaatctatc tttaaaaata atacatcatc aaacctaata tacgatgatt cgttatcgca
    55861 tgtgtttgct cgatacgtcc gctctctaag tcggtcgtgc cataataagc tgtcgccgga
    55921 caatactcga aaccgaactt ccaatgcggt aaattatacg atacgtttaa gctgacggtt
    55981 attaattgat cgatatccaa tcccatacca tacaccttat ccgctgagac caaggacttc
    56041 ccggttccca aattcttcgt atatccgacg aaaacacccg gtctccattt cgttccatag
    56101 gcgaaattca cccatgtcgt agaatggcga aaaggcgtat atccctgttc gcccgtacgg
    56161 gagtccaccg agctcacccc gtaaccgccc aataaagcgg tatgatccaa ggctgaggcc
    56221 atcaaggttt tcgccgcaaa ggtatagttt cttccgctat acttcaaatg tgcctcgtaa
    56281 gagaatgcgg tcattcgctc gttcacctta aaagtttgct ccttccattc cgtggaagta
    56341 cggggtttca aggagatcat atgagcgccg agccccatca accaaccatc cgcagggata
    56401 aaatccgccc ccacgaacat ctccggaatg caactattct tgatataatc ctcgctcatg
    56461 cctttcggtc cgctggaaag gtattgtaat tgccacaaca cggaagccgt caattgtacc
    56521 cggctattcg ccttatactg gtaacggatc tgagggctac ggttgaaagg ctggaacggc
    56581 gctccggtgg aaagattcaa gacatccggc atcacggcgc caaacaaggg atgccacgtg
    56641 attcctacta ataccgccga ttttccccaa tccaagttta cgtatgcctg ccggatacgt
    56701 aacatcgtat tactaccgga aaaaccgccg aagtccgtct ctatcttagc ggaggaacga
    56761 gccttaccaa tatcgggtcc cgtcacgtcc aagcccaagc gggaagtgaa cgtatagaaa
    56821 ctgccattcg gcgtggcgtt caaatccttg ccatccgcat caaaactctt atccaaagga
    56881 tagagataaa agttcccatc gatcggagcc atattagccc gggaattgta gaaaagatct
    56941 ccacggacga agccgtagaa tttgtaagtg aagttttttc tttgcgctgt cgtagaaaat
    57001 aaggctagca tccccacgag caacagggta atccgtctca ttataattca gtttgttatt
    57061 tttcttacct tataagccgc gaatgtatat atttttacgg attcaatttg aagaaacgaa
    57121 atattatttg ttcctttgct tccaagttgt aagccttaaa ggtcaaatta gattaatatt
    57181 gtaaacacca gataaagaaa atgagtacta aaaagttttt gctagaagaa aaagatatac
    57241 ctacggcatg gtataatatc gtagcggata tgaagaacaa accgctgccg atcttaaatc
    57301 cacaaactaa acagccctta aaggaggaag atttatatcc tctattctcg aaaggcgtct
    57361 ctcatcaaga aatgaacacg acagacacat ggatcgagat ccccgatgaa gtacgcgagc
    57421 tttataaggt atggcgaccg actccgttgg ttcgtgccac cggattggaa aaagcgctgg
    57481 atacgcccgc tcatatctat ttcaagaacg agagtgtaag cccgatcggt tcacataagt
    57541 tgaattcggc cttggctcag gcttattatt gtaaacaaga gggtacgaca aatatcacga
    57601 ccgagacagg cgccggacaa tggggtgccg ctctttctta tgcggcaaaa gctttcggct
    57661 tggaacttgc cgtttatatg gtaaaggtta gttaccacca gaagccctac cgtcgttcga
    57721 tcatgcagac tttcggagca caagttgttg cctccccgag tatgagtacg aaagccggac
    57781 gtaagatctt gacagaccat cctaattatc aaggtagtct aggtaccgcc atctccgagg
    57841 cggtagagct ggccatgcag acaccgaact gtaaatatac attaggtagc gtattaaacc
    57901 acgttatgct gcatcagacc gttatcggac tggaagctga gaaacaaatg gaaatggctg
    57961 gcgagtaccc cgatgtcgtt atcggttgtt tcggtggtgg ttccaacttc tccggtatca
    58021 cattcccatt cctgcgccat aaactaacgg aaggtaagga tatccgggtt atagcggcgg
    58081 aaccggcatc ttgcccgaaa cttacaagag ggcaattcca atatgacttc ggagatgagg
    58141 caggctatac cccattaatc ccgatgttca cgttgggaca taatttctct ccagcgaata
    58201 tccatgcggg aggtttgcgt tatcatggcg ccggctccat cgtcagccag ttgatgaaag
    58261 acgaattgat gagcgccgtg gatatcaagc aattggatac cttcaaggcc gctactctat
    58321 ttgcgcaagc ggaaggaatc ataccggccc cggaatcatc ccacgctatc gccgcagcta
    58381 tccatgaggc agagcaagcc aagatcgaag gtaaacctcg tacgatcttg ttcaacttat
    58441 cgggccacgg cttgatcgat atggccgctt acgaccaata tctatccggt gatctaacaa
    58501 actatgaggt aacggatgag gaagtagcta acaatttgaa agatttggag aaaatcatct
    58561 gataaaaaca agaaaagggg cgataccaaa tcgccccttt cccttatttg tctatgaaag
    58621 tcttaattta aagtatgtat tatgagaaaa tttcttcgta attagtactc ggaataatca
    58681 tgttctggac atttaagcta aagtttttct ttttcttatc ccacataccg taatttgtct
    58741 ttatctctcc actttgatca tcatattgat aagtgatctg atagaatgga acccattcat
    58801 cgtttgtccg atcccaacga aacgctttct tctcggaaac cttgccgttc tcgttgtact
    58861 ggaactcata tcttacctgt ttgttcaaca gtccgttttc ctgtaagaat accactttag
    58921 agataatctt accattctcc tcttttgtat catatagata atctttagga gacgctgcgc
    58981 ttatcgctaa actacacatg aaagtaaaaa caagcgcaag aatactttta ccccaaactg
    59041 atgtcttcat actattttaa tttataaggt tactatcatt ttgtaccgcg aagtaaggaa
    59101 gtttcccgac aatcaccaaa agcaaagtga caaatcgtta gtaatatcac aatatttaac
    59161 acattcaaga ccttcattcc cttcgattct cccatgttta ctgacatatt gtaaaccaaa
    59221 tcgtaagttc ccccgatttt taaatatcta ttatttacca ccagccggat gtaactttca
    59281 aaagaaaact ttagacaccg cttttttaat aaattaaaaa tctattgatt aataaatata
    59341 ttcttacttt tgcaaaggca gaatgcaaat tgatttcttg acatgcgaca aataatgaaa
    59401 ctatttatca catcctttct ttttatccta ttctcaggat gtacaaagga tgtatatgat
    59461 ccttccgata aaattccggg agaaggtact aatccattct caaaggtaac aatttcctct
    59521 aatttcgatt ggtcgatgat acaaatatcc caccttaccg tacaatcttt cgacccctat
    59581 gatggcacct ataattatct ggtagaagta tttgataaaa gtccggaaga tcaagatgcg
    59641 aatcttctcg ctaccggggt ttgctcaaag aaaacgcttt tcgataagaa aattatctat
    59701 ccaaagggag agtcggatca agtttacata aaattgacga cccctaccgg atatcaagtt
    59761 accgctcctg tcaccttaac accgggtaat gataatgtct gtgctttcga ttcgttagcc
    59821 gtatcgcagg aaacaaccgc tactccggtt agccgtaccc cgacccgaag cgtgtcttcc
    59881 acctatacat ttataataga agactctttc cctaattacg gagattatga ttttaatgat
    59941 gccgtgataa aagtccagat ggaaacttcc atgaaagacg attatgtaca attcgccaat
    60001 ataaaactga ctttccgtcc attaggcgga actaagcggg ccggagcttt catccatctc
    60061 cccggcataa agtccaaaga catccaaaaa gccgagttaa atggctggac cacgactcca
    60121 gaatcggaaa ccgagactcc ggtttatgcc ctatcggatg atatacatgg attattctct
    60181 tttcatgaaa tgattaatac agataatgac cttccatata ggggaaagca agaacgtttg
    60241 atcacctttt cgttcgcagc cggtgcctta aaagatttga ccattgatga catcgatctt
    60301 ttcacgaccg tattaaagcg ggaaggagag gtcttacgca cggaaatcca ccaacgtaat
    60361 tatagctata cccccaaagg ggtcagatac cgttattact caaatgataa ttgcatatgg
    60421 gccttaatga taccggatga tttcaaatac cctgtggaac atgcttttat tggtgatgcc
    60481 tatccggatc tattgaaatg ggtaagtgga gatagcaaac atgtacaatg gtataaaagt
    60541 aagaatacag ttgataagtg gatttatacc cgagaacaat aacaacctaa aatcctccgt
    60601 aaaatgaaaa cgaccgccat cttatttctt gcctttctgg ctttatgcgt tcagtgctca
    60661 gtgccggaaa acaagagtac gaaaaaagag attagtactc agccgataaa ggtgggtgta
    60721 ttcgatgggc atggaggagc acagacctgt atttgggaaa ctgtcgccgc tatccggctg
    60781 gacccggaaa tggaggtacg taccattact acagcagata tagccaataa tgcgctcgat
    60841 tcgatcgacg ctattattat cccgggagga agtggcaaaa gtcagtactt aaacctaggg
    60901 accttaaatc aacaacgtat caaggacttc atcgctaaag gtaaaggggc tgtcgggatc
    60961 tgtgccggag cctatctatt ctcgaatact cccgattaca cctgtataca gctaaatgga
    61021 cagcaagcga tcgacatcga gcatgacaac cgagggcatg gattagcgaa attcacctta
    61081 tgcgaggagg gtaagaagat attccccgaa ttagccgacc gcgatacgag tttcgtcatt
    61141 tactatgagg gaccggtatt tataaacaat ccggctgata cgatccaaag caacacgctt
    61201 gccatcatgg aaagcgatgt gcatgaggaa ggaaacgccc cggctaatat gacaaacggt
    61261 aagccattct tcgtagccaa taactacggg aaagggcgtg tttttagttc catcgcccac
    61321 cccgaaggta ctcccggcat gatgtggatg atcccccgga tggtacgttg gaccttgaat
    61381 aagcctttta tcccttatca atcctccgcc gtacgtccag acctgttcaa tcatgaatca
    61441 ttaatggcta ccgatgattt aaagcaggaa gaaaaagcct ttcaaatcct tttaagcgga
    61501 gaaagcgagc aaaaggttgc cgccttggat tggctggaag cacatcattc atgggacgcc
    61561 aaacgatggg tacaaggatt gctttatgac gcttcacccg ccgtccgtat ccgggcagcc
    61621 cggtatatag cggataccca ttacttacct ttcttaccca acttacaggc ggcctaccgg
    61681 acagaaaccg ataaggcgac ccaagaagag ttaaagacgc agctggagaa actaacagcc
    61741 ctacttcctt aggctaggga gatttaaact ctccctagat attcatctac cgtatagttt
    61801 aagaaacgat tgaatggtaa taacaattta aagtcatcca ccgccttatc catccaatcc
    61861 gtagcgtaaa agaaattatc cggcttataa gacaccacgc tgaaatcctt atgcttcatg
    61921 atataaccat aaggggaatc cattggatag ccggcaggca tgcgtttcag catctccccc
    61981 tctaacaccg gaaatgtttt cttaaatgta ggttcctcga taatagccgt aaattcctcg
    62041 atatgatcgt atatatcctg acgaagtttc tttaatagcg caggtggcgg gcaccataca
    62101 ccaccggaaa gcaagcaacc tcccggctcc agatggatat aataaccacc ccgttcgctg
    62161 gcacgaccac cttgggagat gtaagcggcg aaatgacatt tataaggagt cttatccgga
    62221 gagaaacgga tatccctgta tatccggaac aaacaatctt tcgcctccaa cccggctacc
    62281 tcgggatcga ataaagagat acgaccgatt aaatcctgta cctcatcgat aaaaacctta
    62341 cgtagcgcat cgtaacgatt tttattgtct tggaaccatt cccgattgtt atggctcctc
    62401 aactctgtca agaactctat gatctgttca ttcataactt tctattttta atccttacaa
    62461 atgtaagaaa tattagaaac tgtaacccag attcagataa aattgcaggt tattattccg
    62521 gttcgacaat ccaaagttcg tattcatcgg accgactata ctgttataag cataaccgat
    62581 gctacctccc caaacgcttt ctcccttgaa gagatcgaag aaattattct catggatcgc
    62641 ataattagcg atcaaagaga tataatgccg ttgcccgata cgctgacgca agtttaagcg
    62701 gacaatcgcc acggaattat cgaatatctc catatggttg atcccagcga aagggagttg
    62761 ctggggaaga taccgttccg gcatatcgcc tcccaccaca ttcaaaaagg gataagccgg
    62821 atctttcccg atcaacacac gcccatcgat ggaaggtaac aggctcaaat gggaagtcag
    62881 cggcaatacc gacaggaagc tgagcttcaa ggcggagaag aatgtatgtc ctttataggt
    62941 cacgaagtta tccgtataaa tggaataatc cgcttgcaga gaaacgcctt tactcgggaa
    63001 gtaacgacga tccaacgtct ccagatgggc ttgagcgaaa tagctgataa agccttccgg
    63061 ttttacttga tacttttggt tttctgccgt ataaaggaat gagttataat cgaaatactc
    63121 ataacgggct cctagcttca acttgaaatt cagccagttc atatccgaat acccgagttc
    63181 cacgaaatga tggcgatacg tcgtatttac gatcttattt cccctgttat acacgtcgag
    63241 gtcatggtac gtgaacatgt aagacaggtt aatattacgc aatggattac gctctatcgc
    63301 atagtccacc cgcccataca tacgtttccc gatcctcccg gttacggaga acttcgaatg
    63361 gtaacgggcc cgattgtcaa aagtcacatt cagcaatagg gcgacgatat cctcgctatt
    63421 gaaattcagg cccacattaa tcgcgctatt tgatttttcc tgtaccgtaa gcaccaaatc
    63481 ctcctgcctc tcgccgacta atttatagct tacattcgag taaaggtttg taccgatcac
    63541 gatagacatg gcttcctgca atttcttcac ggtaagcaag ctattctctt tcaagccgct
    63601 gatttgcgtc aaccatttct catcacgagg atctatacct tcaaacaaga cacgccggat
    63661 atgaaacgta tcggtagggg ctaccggata ggaatgtact aatctctttc ggtgcatatc
    63721 cgaactatcg gataaaccaa tcttcttctt taaggcaaga atctcatccc attgcttgcg
    63781 ggcgacttgc tcaccccggt caatcaaggt atccaaggcc gtctccccaa aactagcgga
    63841 attataaggg tctgtattcg ggcggaacaa cagatcggtc tgttccttat tcggtccgta
    63901 tttctcataa ccatgcaagg cgacgatctg ccctacgata tcccaagggg tatttatccg
    63961 ctccaactgt ttcaagtcgc tagtacctag atctacgcca ataatgatat ccgcccccat
    64021 atcccgtgcg acatccgccg gatagttatt cttgatccca ccatctacca acaccatgct
    64081 atccaaacgt accggcgcaa acacggcagg aatcgccata ctggcacgca tagccaacgg
    64141 aagacttcca tgatggaaaa catattcttg gccgtccacc acattcaacg ccacacaagc
    64201 gaaaggtata ttcaattgat tgaagtccac ggaatcatga tagccgatcg ttagattcga
    64261 gaacaggttc tggagatttt gcccttttat catcccttgg atcgctatct cttttttact
    64321 ccgcccaaaa gggagtgaga atacataacg ctcggaattc tctttctccg gaaaagtaag
    64381 gctactacgt ttcacccggt cgctcaataa catactccag tcctgcaatc tcaccatgct
    64441 atcgatttcc gcagcattat atccaacgga atataagccc cccacgatag ctcccatact
    64501 agtgccggca atataatcaa tcgggatgcc ggcctcctcc aataccttca acaccccgat
    64561 atgagcgaca cctttcgccc caccgcctcc cagcaccaag ccaacctttt tccgctcagc
    64621 catcacagaa ggcaccaaca tcaacccaac caaccacaat aaaaggaact tcctcatcta
    64681 gatattcttt ccggcaaatg tagctggttt actcgaaaac gcaaacggat tcatctagaa
    64741 taaaacgtat gtttacctat atataaagtt tatcgctatc tcatctattc tataaaccat
    64801 gccgtgaact gtataaacca aggcgtggtc tgcacattcc acggcgtggt ttatacagtt
    64861 cacggcgctg atttaagaat aaatacttat tcgctatgga atgtataggt tatcggagaa
    64921 ctatttcaac aagagaggaa cattttattt ccggaacata agtgggcaat cgatagtatt
    64981 tgatacggcc tccctaaaat taataggcat ttctcgctaa aatcgattta cgtattatga
    65041 atcaagtatg tacgtgttta tcaaaaaata atatagccat caacttactt ttttccagca
    65101 aggtagcagc cggagcaata tattactttt tctttttcag cagcatgacc acaggattcg
    65161 actcttcatc caagtttgcg gcgatctcct tcaactttcc ttttagctgg cctttctcgt
    65221 aagcctcaac taagtccggg gcatctagag tttggcagat agctatttcg gggtttcttg
    65281 gctctgatgt tagagagact tcttccttat tgatgaaatc atcattgtat agaatatagc
    65341 tgaataaggc attttcttgt ttatcataca ccagatcttc accaaggaaa cctttaaacg
    65401 tcgtaaagtc aacctctttt ctcatggttc tcataaaaca gtagcgatcg gtgataacgg
    65461 ttggaaaaag aaagactttc gtatccatgg aggatatgga agggcttctt acgataaaag
    65521 gactcagatt accatccggc aagtaatgga atatggtatc agacgatgta ttgacaagta
    65581 tccatttatc ccgatccggg aacgtaagat aaaattccgg cgtaatgaca aactcccctt
    65641 ctgtcacaac cggagtctca atacccttag agggaatctg gatctcatgg gtgatacggc
    65701 catcttgttt ggaaataatc aaatggcact cccgcttgcc tttttccgat ggataactct
    65761 tatagcaaat caaatgatca cgatcataat taaatatata attataataa ctggtatccg
    65821 tgaacttaaa actcctttta tagtttccca ataagtcata gacacctatt tttctcgccg
    65881 gattatcctt gacgaatatc tcatcgttat cctcatccaa gacaagccct gtaagctgcg
    65941 tgtattcctc accgctttgc cctaaacggt ttatcttcct aagtcccttt ccgtttttat
    66001 cgaaaacaag aatatcccca tcactgcccc gattcgtcac cagcatgata tcctttccga
    66061 tcgctttcac ggcaccttta gttataaaat catccgtggt ttccaacgca atgtattcca
    66121 cgtccataag atcttgaagt atcaattcct tttccggata atcggccatg acatcaaccc
    66181 ttataaggtt atcgacagag gaagcggacc gattgccaca tcccatacat ccgactaaag
    66241 cgagcagcat agccactgcg ttcgtagtta attttctcat ttttataatg tttaaagtct
    66301 ttcgttcgat gtcatttctt gctctttagc gctttctctt tgttcatcat ccgtatcatc
    66361 tcttttacct catcggatgt ctccggcagt tgttggatca gagattggag ttcatctata
    66421 gaaagctggc ttttccggtt atctggagcc agcatggttt gctccgtgat accccgtttg
    66481 gacatatccg aatttaatga ctccaagaaa ggccgggtaa aagtcaggtt actcagatcc
    66541 gactcgtttt tcaacagttc cttcgcgtaa gtcacttgag cgaatacacc tctctgtagc
    66601 tcctccgcat tcttgaatcc ggagatatcc ggatggctat ataggttcgc aatctcacga
    66661 agcaattcta cacgagtacc cttcaccttc cacgcccgat aaagcagacg ggccgcctcc
    66721 tctatcttac ccgagcttct ggcgctcatg gcacgaatct ccatgaccat ctccgattcc
    66781 tccggcaatt gattgatcag gttacgcaaa tccacgatag agatcttgct ctttttccca
    66841 tccgggtcta tcatagtctc ctccgccaca ttacggaaaa acatatcctc atagaaggat
    66901 tgcagaagcg cccggctaaa caccatcatc ctctcgtccg cttttttctt taagctctca
    66961 ttcatataaa gtaccaagat aaaaagacct cgctgacgat cctcctcgct ctggaattta
    67021 gacacgtcaa tctcactata catatgcgag atcgccgcca ggaaatccag tcgttccgga
    67081 ttcttcttcc atgcctcata gtagagacgg gacgcttcct tatatctccc gtctttttgg
    67141 taagtctccg cacggaaggc caataattga tttaccaaga aacgattggg ttccaatccc
    67201 ttttccgccc ggtcaaataa gtcgtaagcc cgcttccggt catacgtctt acccaaggcg
    67261 gaacccaata agaggcatac ctcgaccgag gtcgtatcct gctcatatgc catatccaag
    67321 atatctaccg agggcatata cagaccggca taatacttcg aggctccccc atatttcaag
    67381 gtaaggtagg tggaatcacc atcagccaac aaactggaat agacagaatc cgcctgaaca
    67441 aattgtttca cgatatatag ccccaatcct ttactacgca ataattgacg attcccggga
    67501 ttataaaaca aggcggtatc gcaaatcgct attccttccg atatataatc cgggctacta
    67561 gcccccatcc gatacaatga attcactaac gcaaccgcca accccgcatt ctcacgattc
    67621 aagttatacg cctgaaaata agcggtcgta gcagaaggat attgttccat tcgagtatag
    67681 caatcgccaa tcgcacggta taagacagta ttatcctcat tctgagcttg caatttctca
    67741 taggcatcaa ctgctttctc atactccccc aattggaaat acagacgtgc caactgataa
    67801 ttagcgtaga agttcgagct atcggcggat aagacctgat gaaaatatcg ctcggcatcc
    67861 tccgcacggc ctaagttcgt cgccgtccga gccaagatgt ttaagatatc caagttcgtc
    67921 gtatccatag aaaagcaaag acggtaatag tcataagcct tctgataccg aagcataccc
    67981 tcataagcct gcccgatagc gttcataatc tcataattcg aagaatcggc taatgtaagg
    68041 ctatcagcat gagcgatcac agccgcatat tgcttacggt tcaccaagtc ttgccaatta
    68101 aactcttgag cattcccggg aaaaataagg caacaaagta acagaactgt aactaaatta
    68161 catttctcat tcatatctgt atgtttttaa gattactgat taagcgacca acatagcctc
    68221 tattcttatt tcactgtaac cggaaagtaa taggcaccgt atataagacg cggaccgcct
    68281 ttccgtcctg acgaccggga gtccaccggg gcatcattcc gatgactcgc aaagcttccg
    68341 catccaaaga gggatctatc ccccgtatga ttttaggttc cacgatattt cctttcttat
    68401 ctactacaaa cgaacagatc acacgacctt gcactcccgc ttcctgcgca tctgtcggat
    68461 actttatgct ttgagcgata aacttcaata attcacgatc ccctccggga tattgcggca
    68521 tcacgtccac taccgtcaaa gtctcttcct tcgtttcttc taccggactt ttcaaacgga
    68581 acgtaatcgg gaccgtatat ttcacggcga ccgcctttcc acgttgcatt cccggattcc
    68641 agcgaggcat agtgtttatt acccttacgg cctcctcatt caataaagga gtcactcccc
    68701 gaagcacctc cggattattg acggaaccat cacgcccgac gataaacgag cagattacac
    68761 gcccttgctc cccgttatcc tgactctctt tcggatactt tatattcgtg gctatgtatt
    68821 tcaacaactc cgcatcccca cccggaaaac taggcatctt ctctaccacg gtaaatactt
    68881 gctcgttcat ctcacgggat ttggaagata aggacaaatg ggtattattt gtcatatcag
    68941 cagccaagac ctcttgagac tcccttcctt gatagctgca tcgcaaaatc gcattcgcag
    69001 ggacctccaa agagaaagcc cctttcctat ccgtgatagt cccctcttta ccgcccttca
    69061 ccacaactga tgccccgatc aaaggcttcc cggtctcatc aaccagaatg cccgtagccg
    69121 tcaccatagc gttcgagacc gtagtctcat tcgccagacg gacagtcaaa cgggctaccg
    69181 cctcgatatt acttaacaac atcaagatcc ctaccaatgg aataaatatc agatatttcg
    69241 tacgtacgat acccgggctc cgcttcttgt tcatcatcat aatccggttc ttcagatgca
    69301 gcacattgaa actattatac aaagtagtaa cggactgatg atgagccaat cccaataaat
    69361 ggtattgata gctcttacta tcgtaaccgg actggatcac cgtgttatcc gccagatact
    69421 ccagattgtg cctaacctca cgcttcaata accatacaaa aggattgaac cagcaagcca
    69481 tacacatcat ctcgctcaag atcacgtcaa tcgagtgcca ttgggatacg tgcgtacatt
    69541 catgtgtcaa tatctcatcc gtttccttat ccgaatgact ctccggatgc aagaagacca
    69601 tacggaaaaa ggagaatggc ccggcggcct tccgcaacgc ataaaccgga gtttcatgaa
    69661 taacaacacg ctcactggta tgagccaacc ataagatact gcttaattgc acgagaaaac
    69721 gtccgcataa gaacgctacg atcccccaat aaataaaccc caaagatccc agcaaccatc
    69781 cataccaatc cacggacgcc gcggcatccg ctttcgccgt cgcctcaggc aacatagcgg
    69841 aatacatata aatcacgtcc gctataggct cttgttgcct tacccaatct tggatgttca
    69901 gcaaaggata aaacagagcc aagccaaaga acgccagcaa gatcgcacga cgtagcttga
    69961 agaacgtgtc cttatagaag aacaaccggt agaaggcata aaagagtaca aaggctacat
    70021 ttaccttcaa taagtaggca aattccggtg tcatggtatg tgggatttag gttattcttt
    70081 tcctttctca atcaaatcga tgatatcctt taaatcatcc gtagagattt tctgatcttt
    70141 cgcaaagaaa gaaaccattt ctttatacga gttagcgaaa taattcgtta ccacgccgcc
    70201 aaggaacgta cgtttatatt ccgtttcctc tatcaaagga cggtattcat acgtatttcc
    70261 ataacgtttc gccttcacgt acttctttcg ctccagattc ttgatcacgg aagcgagcgt
    70321 cgtataagga ggtttcgggt cctcgtattt ggccagcaca tctttcacaa aacaaggacc
    70381 gatccgccaa atccagcgca tcgcctcttc ttcctgcatc gttagcttct ccataaatct
    70441 tatcctttta tttaatgtat atccacaaag ctacgaaata gtcgtaaacg gcatgcggaa
    70501 ggcacgttaa ttaacattaa ataagaatca caagacctgc aatcgtgaat tattgcaact
    70561 taaacgtgat cggcaccgta tatttcacgg ctaccggctc gcctctttgc gtgcccggtg
    70621 tccaacgagg catcatttgc aaaactcgaa ccgcctcttg gtctaatgcc ggggagattc
    70681 ctctaaggac cttgtaattc gtaagcgttc catccttcgt taccacaaac gaacaaatca
    70741 cacgcccttg ctctcctttg tcttggctct cttgtggata ctttacattc ttggctataa
    70801 atttcaaaag ctccgcatca ccgccgggaa acttcggcat cacctctact accctaaata
    70861 cctgctctcc attttccagc gtatcttcgt cctccgcttc cacctgtact tgctcttgtt
    70921 tttctgcctt tgttacatct gtcggaacac tttcttcttt ttgttccgaa gactgtccgc
    70981 atcctacgca catcgccaaa gcgaacagga tgatcattgt gttcataatc gcctttttca
    71041 ttttcaatcn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    71101 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnc cggaaactca
    71161 atcatatctt gcacaaagat atccttgggg tccttttttt caattcgcaa attactcatg
    71221 tccgtaacat ccaacgaacg aatcacttcc gcatccgagt ttttcagatc aaggacacaa
    71281 gccgcactta ttcgatccgc cgagatacag aagaccgtat cattactacc ggtcttaaac
    71341 aacacagagt tttgcgcatc agaataagcg ggggcgatac ttgtcgtgaa cccgctcttc
    71401 tcatggggta ataaaaagga ataaaaatca ttcttgatcg ctatcgtatc ccctttcccc
    71461 gaaaataggc ccaatccgaa tccccctccg ttgaaaggct gaaaagggaa tgatatggcg
    71521 gcgaaacgat cctttccgat atgacgcata tagattaccg aatactcatg ggtggattgt
    71581 ccgataaatt caccttctaa cgtatattcc caaactcgat tattactaaa taaaaaaagg
    71641 cgatcattac gttcgtccac ttggatacat ggcagaatac cgctaaattc acccggcccc
    71701 tgcccttctt ttaccaacgt ccggataaaa cgcccttgcc gatcgaacag gacgatacgg
    71761 ggctctttta cgggaagcac atagatatat cgatctgtca cggcataatc ataaactccg
    71821 tctatcaacg aggcatcatc cgtggtcacc tctaaaggga caaaagtaac ccccttgatc
    71881 tcatcgccta attccaatag ccccggttta tccatccccc ctcttatatc cgcggttaaa
    71941 agagaggacg cttccgttgg cgaagaaccg catgacacga aacaagaaac gacaaaaaca
    72001 ctatttaaat aaaacaagat agaggctaac tttacacttt tcataaccat gcttttttgc
    72061 ctccaaaaat atcccgtata tctcacaaat cacataataa atgagaacaa aaatgagaac
    72121 aaacctgcca agaccgctat aaatatataa taatcaaaag tttgatataa actccacaaa
    72181 tgcctccgta gaaccttctt tcttaaaaat cttccggaat agacgaggac gaagtaccga
    72241 actattatat ttcaataccc gtgtgatctg gttggcggga acaccgattt tcgtgagcat
    72301 acaggccttc aactccgtat cggaaataac aggatatagc tttttcagcc gtaaggtaaa
    72361 gtcatcataa gccttattca acaaaacctc caaaagctcc caatcctcag agataatctt
    72421 gccggcatcc cgatcgtgaa acttctcata gacctccgat ttccgcaaga tcgcgacaga
    72481 taataaatgc ttactctcct tattaagaat cgactcgtta caaatttcca gccgttgttt
    72541 ttccaattgt aaggaaacca acatcaactc ttgatccttt tcttccttta ttttcgtaat
    72601 tcttttttcc aaaagggtga tttgccgttc attctcttct ttttcttctc gcatacgttg
    72661 ttgctggcta gcaatcgaac gtcgcaaggc ttcttccctt cgaagagcgt tttcctgcgt
    72721 atttctccat cgccgataaa ggaggaagca aataaatagg attatgccga taataaatgc
    72781 gtacagataa cgctcctgtc ccctttgtaa tagcatcaac tctttcttag acaagtcctc
    72841 acggatcggc cttacatcat agcgggaagt gatctgataa atcgattctc tcgctgatag
    72901 tgatccgata gaatcccgta acatctcgta tttcttgacc tcggtcagta tccggtcttg
    72961 tccggccgca tcgttcaata actgatattg agcactcgct tttctcaaaa aagacatagc
    73021 cttgccatat aattcctgct cggcgtacag catccccatt tggttatata accttcccca
    73081 gaattcataa tcccaattct ctccctcata ttccaacgca cgtaaatagc attccaaagc
    73141 tagggacggt tgatccatat cctcatagac tttcccccgg taaaaccaag ctttgggagg
    73201 ccagtaacag cctcgtgtcg tcctataata atccgtagcg atagagatta tggaatccga
    73261 tgtatgcctc aatcccgcct catcccgtga ttcggtccat aacagacaat aacgggcttt
    73321 ctctcgaagc gataatccat tgatatccct cactttctct aataacacca aagcactgtc
    73381 cggatgatgc ggaatcaatt tctctacctg ccagaacagg ttgccatgct tgtcgctcct
    73441 atatgaaaaa agcacaagaa ccaagatcac gatcgtaaat aataagatcg taaacttgat
    73501 ccctatggaa aaatgccgtg acccattcaa atccttacgc atataggcaa atgtatataa
    73561 attattcata aggaaagcct tttccttccg cattattcca tgtgtcggga cacatgccct
    73621 gacctctccc attaatgcag aaatatttct ttaatcgttt gcgcaatata tggatttagc
    73681 atacctttgc gtgataatta catagtttaa gtagaaattt ctaaatacaa ttaaataact
    73741 taaattatta tcttatgtgg ttacttaatt cttctatcgg gaagaagctg ataatgagta
    73801 tatcaggcct ctttcttgtt ctgttcttat tgttccacct gtcgatgaac gtggcggccg
    73861 ttttctccgg agaggcttat aacatggttt gttcgctgtt gggctctaat tggtacgctg
    73921 tggcagctac tctcgtattg gccgcaggcg ttgtgatcca cttcgtgtac gctatcattc
    73981 ttaccttgca aaaccgtaag gcacgtggta acgaccgtta cgctatcaac gctcgtccga
    74041 aaggcgtgga atgggcatct cagaacatgt tcgttttggg tttgattgtt atcctgttca
    74101 tgctgttgca cttcagccag ttctggtata agatgatgtt cgccgaattg atcggtcatc
    74161 acgaagttgc attggggtca gctatggtat ctccacaaga cggagccgct tttatcaact
    74221 attacttcca aggtaatgcc gtgatcactg ttctttattt gatctggtac gtggctttgt
    74281 ggttccactt gactcacggg ttctggagcg ctatccaaac aattggttgg aataatacga
    74341 tctggatgaa ccgttgggaa tgtatctcta agatcgtagc tacggttatt tgcggacttt
    74401 tcgcgatcat tactatcatc ttcttcctaa acggagtagg tgcttaattg caagctacag
    74461 gttttataat taagaacttt tgaaattaaa tcattatgtc tgaaataaat tctaaaatac
    74521 ctcaaggccc gttggctgag aagtggacta attataaaaa tcaccagaaa ttggtgaacc
    74581 ccgctaacaa gcgtcgtttg gatgttatcg tagtcggtac aggtttggcc ggagcttccg
    74641 ctgccgcatc tttggcagag atgggattca acgtattgaa cttctgtatc caagattctc
    74701 cccgccgtgc gcactctatc gccgctcaag gtggtatcaa cgccgctaag aactaccaga
    74761 atgatggtga ctctgtttac cgtttgttct acgatacgat caaaggtggt gactaccgtg
    74821 ctcgtgaggc taacgtttat cgtttggctg aggtttctaa ctcaatcatc gaccagtgcg
    74881 tggctcaagg cgttcctttc gctcgcgaat atggtggttt gttggataac cgttcattcg
    74941 gtggcgctca ggtatcgcgt acgttctacg cccgtggcca gacgggccag cagcttttgt
    75001 taggtgctta ttcagcgttg agccgtcaga tcggtttggg taaggttaag atgtacactc
    75061 gtcatgagat gttggatgta gttaaggtag acggtcgtgc tcgtggtatc atcgcccgca
    75121 acttgattac aggtaagatc gagcgttacg ccgctcacgc tgtagttgta gctacgggtg
    75181 gttacgttaa tacgttcttc ttgtcaacca acgctatggc atctaacggt tccgccgcat
    75241 ggcaatgcta caagaaaggc gcttacttcg ctaatccttg tatggttcag atccacccga
    75301 cttgcgtacc ggtgaaaggt gacttccaat ctaaattgac tttgatgtcc gaatccttgc
    75361 gtaacgacgg ccgtatctgg gttccgaaga aactggaaga cgctaaagct ctacaggccg
    75421 gaacgaagaa aggtaaagat attcccgagg cagaccgtga ttattatttg gagcgtcgtt
    75481 atccggcatt cggaaacttg gttcctcgcg acgtggcttc tcgtgccgct aaagagcgtt
    75541 gcgacgcagg tttcggcgtg aacagcacgg gcttggccgt attcttggat ttctccgacg
    75601 cgatcaatcg cttgggtaaa gaggtcgtta agcagaaata cggtaacttg ttcgatatgt
    75661 acgaagagat cacgaacgat aatccatacg agactccgat gatgatctac ccggcattgc
    75721 actactcaat gggtggattg tgggttgact atgagttgat gacctccatt ccgggtctgt
    75781 tcgctatcgg tgaggcaaac ttctccgatc acggagcgaa ccgtttaggt gcttccgctt
    75841 tgatgcaggg attggccgat ggttatttcg tattaccata cacgatccag aactatttgt
    75901 ccgaccaaat ccaagttcct cgcttcagca cggatctgcc ggagttcgtc gaggcagaaa
    75961 aggccatcaa ggatcgtatc caaaaattga tgaacgtcaa gggtaaagaa accgtagaca
    76021 ctatccaccg caaactaggt catatcatgt gggaacatat cggtatggca cgcgacgcaa
    76081 aaggtttgca agaagctatc cagatgctga aagacttgaa gaaagagttc tggagcaacg
    76141 tattcatccc aggcaacgca gacaacttga ataccgagtt agagaaagca ttacgtgtag
    76201 ccgactttat cgagatcggt acattgatgg cacacgatgc tttggaccgc gctgagtctt
    76261 gtggtggtca cttccgtacg gagcaccaga cagaagaagg tgaggccttg cgtcatgacg
    76321 ataagttcat gtacgtatct tgctgggagt accaaggcga ggacaaagat cctgtcatgt
    76381 tgaaagagga tttgaactat gagttcgttg ttcctcaaac acgtaactac aagaagtaat
    76441 aatcatcaat ctcagaaaaa attagaatca tggataaaga tataagtgta acacttaagg
    76501 tttggcgtca gagaggtccg aaggagaaag gacagttcga gacatacaaa attgagaaga
    76561 tcaatcagag tgtctctttc ttggaaatgt tggatatctt gaacgagcag ttggtcaacg
    76621 agggtaagga accgatcgta ttcgatcacg actgccgcga gggtatctgt ggcatgtgtt
    76681 cattgtatgt aaacggacac ccgcacggac cggcaactgg agctacgact tgccagttat
    76741 atatgcgtcg tttccacgat ggagagacga tcacgatcga accgtggcgt tccgcaggtt
    76801 tccctgttat ccgcgacttg atggtagacc gctacgctta cgacaaaatc atccaagcgg
    76861 gtggtttcac atctgtcaac acaggtggtg tacccgacgc taatgcgata cctatcccaa
    76921 agaaggacgc agacttagcc atggacgctg ccgcttgtat cggttgtggc gcttgtgctg
    76981 ccgcttgtaa gaatggttcc gctatgttat tcgtatccgc taaggttagc cagctggctt
    77041 tgttgcctca aggtaaagtc gaggctgctc gccgtgccaa agctatggtc gctaaaatgg
    77101 atgagcttgg cttcggtaac tgtacgaaca cacgtgcttg cgagatggaa tgtccgaaga
    77161 atatctccgt tagcaacatc gctcgtttga accgcgagtt catttgcgct aaattacaag
    77221 actaatattt gattagtata tcatggaaaa ggcgtctttc tctaaaagaa aggcgccttt
    77281 ttgtttttgt tatatgtcgt aaaacataat ttagcattat aacccttgac aggaattgaa
    77341 aagtccgtat atttgcatcg tggttttttc ataatagtat tagatttaag gttaacaaag
    77401 tttggttagg gcttgtcgtg agacaggctt taattgttta tagacctacc ttttaaacat
    77461 ggaccataaa atactgcaaa tagagattgt ttagcgtcat tttatcgtcg atctttgcct
    77521 ttaaagatca tatagtatat gctaataagt attttatttg gcttcttatg ttattttctc
    77581 cgggtgttga tcaaacacaa ggaaaaaatc atgcgccaga taagacaaat ggtaaaacaa
    77641 aaataaaatg gacaaaaaac gaaccaccag ttctttcagg gcaatgagca cggaaagaaa
    77701 actcgagtcg atcttccttt tcgtaacagg ccgatgcaac gccaaatgcg caatgtgttt
    77761 ctatgcccaa gaaatggata agaagcaacc cgacctcact ttcgatgaaa tcaagaagat
    77821 atcagaaacc gccgggcaat tcaatcgatt atggatatcc gggggtgagc ctaccttgcg
    77881 tgaggatcta ccggaaatat tggagttatt ctacaaaaac aaccatatca aagatgtgaa
    77941 catccctacg aacggcttaa aaccagaccg gatcgtcgaa tgggtaaaac ggttccgcca
    78001 gaactgcccg gattgtaata ttaacgtaag cctttccttg gatggcttcg gtacgaccca
    78061 cgatacacag agaggcgtac cgggaaactt ctataaggcc ttggaaaccc tgcgtaagat
    78121 acaggagaat ttcggagatg acggcaaagt cttaaaaaat atagcaaccg ttatcacgaa
    78181 atacaatata gaccagatag aagacttcat gacttgggta tacggacgtt tccgtacctc
    78241 cacgcatacg attgaggctg ccagaggcat gacccgtgac gatggcgtga aaatcctaac
    78301 cgagtcaacg ctacgcaaaa tacaagatga catatcccct atctattctg cttatgcgga
    78361 tcggatggta gcggatacca ccggcttaag gaaaccgatc acacgcttct tctatctcgg
    78421 ccttatacgt accttatata atgtgcgtgc cagcaacata gatcacccga ccccttgggg
    78481 gatggattgt acggccggag agactacctt ggtaatcgac tacgacggac gttttcgtgc
    78541 ctgcgagcta cgggaaccgc tcggaaatat aaaagagtat ggttgcgata taagtaaagt
    78601 gatgaatagc gaagcgatga aacaggaaat agccgctatc ggacatgggt ataaagccaa
    78661 ctgttggtgt acgcacggct gctggatcac ctcatccgtc attttcaatc cacgtaagat
    78721 gattcgctcc gtatataaag gataccggga aacgaaacga ttgaatcatc ccctagccat
    78781 caatgagcag aaactacaaa cgatggaagc caaataccat ctggacatcg agcgtttgcg
    78841 tcaactgaat atccggtaaa caagaccctc atagcccata aataaacgta gcatgaaaat
    78901 actattagta accagaggct cacaaggcga cgtccttcct tatttggcca tagcggccga
    78961 attggaaaga cgtggccatg aggtgaccat caatctccct caaatattcg aggagaccgt
    79021 taaaccctac ggatttaaat acgtattgca gcagtttgac gatatcggcg gcatgatcga
    79081 tagcgcagcg caaaactcac ataaattccg gccattcctt aaatggatga ggaacgtgat
    79141 cgataaacag ttcgatcaat tgattcccct actaaaagag catgatattt tagtatcgac
    79201 caactcggaa tttgctgtcg caagtatcgc cgagtattgc aagaagccct tgatacgtac
    79261 cgcctacgcc ccgttcttgc cgggtaagaa gattcccccg gccgtattgc catttcccaa
    79321 acccaacccg atcatcaccc ctgccatctt atggaagttg atgaaccgga tgaccaattt
    79381 catggtcaaa gacacgatca acaagaaccg ggctaaatac ggactcgcac cgattcgtaa
    79441 ttttggttat catgcgggag agcgttcata taattacttg cttttcagcc agcacctagg
    79501 aaacatagat ccggactgga cgttcaaatg gtcgatcgga ggctattgct tcaatgacac
    79561 ttttcaatat gatgagaagg cttacgagga aatgatatca ttcgtcgaca gcgctcaaag
    79621 ccctattatc ttttttaccc tcgggagttg tagttccaag gatggtaacc gttttagcaa
    79681 agccttggtc gatatttgca agaaacatga ttatcggctc atcatcgatt ccggttgggc
    79741 aaagacagga atcaccttac aagcggataa acatttattc ttaatgaagc agccggttcc
    79801 gcataatttg atatttccgc actgcgacgg cgttatccat catggaggtt gcggcacgac
    79861 ccatagcgta ggaagggcgg gaaagcccca attaatcact ccgttgatta tcgatcaacc
    79921 ctattggtcc tatcgaatcc accaattagg gttagggccg gaagggctta agatagcgaa
    79981 agcgagcgag caggagatcg aacgcaaggt ttgtgatctg gtcaccaatc cgctttataa
    80041 gaaaaatgcc gctcatatag gcgagatgat ccaaaaagag ggaggtataa agaatatatg
    80101 cgactctatc gaaagatttc aatgaggcat aagttcctat tagattttat tacatgttac
    80161 aaaacacaat ttagcactta aactattgac aaataatagt aactccgtat atttgcatcg
    80221 tggttttttc ataatagtat tagatttaag gttaacaaag tttggttagg gcttgtcgtg
    80281 agacaggctt taattgtttt ataaggtctg cttcccgcaa agcccttcga ttacatcaga
    80341 ataatccgat gcgtcaataa agttgatatc ttgtctttta agatcttccc attaatcggt
    80401 ttcgccgtat aggcatcaaa tccactatta atgatccgtt gctcatcttg ggcgaaagca
    80461 taagccgtca ccgcgataat aggcacgcta gcagaaacct tacgaatctc tgcggtagcc
    80521 tcgtatccat ccatgaccgg catctttata tccatcaaga tcaactgagg tttgtgctga
    80581 taaaatagct ccacagcctc ctttccattc catgcatgaa tcaatttata ttcaggcttc
    80641 aatatagact caaacaggcg ataattactg gaattgtcct cagcgatcaa gatcgtaacc
    80701 tcacttcggg cgatcttctc caaagtaaca ggcttctgct cttcactagg aaataattct
    80761 ttcttcggct gaaaaggcaa tgtaaaccag aacttagagc ctttcccttc catagaatca
    80821 accccgatcg ttcctttcat ctgggtaaca atcatctcac agatgcttaa acccaatcct
    80881 gttccttgag cgaaagtgtt cagtttcaca aaacgtccga aaatatcttt ccgtttattc
    80941 tccgggattc cgcagcccgt atcctctaca tagaaccaca acgtattatc atcccgcagt
    81001 ttatagccaa atgagatcaa tcctgcctgc gtaaatttca tggcattgtt caacagattg
    81061 atcatcagtt gggacagacg atttcgatcc gtataaatca cgcaaggctc cagataatcc
    81121 ttaaatgaga tctgtacatc cggattctta ttcttcaaat gagccgattg ctccaaatcc
    81181 ctcaatacag cgttaatatc cacatagtca taagtaaact ccaaggtacc cgcctcaatc
    81241 tttgacaaat ccaagatatc gtttatcaac tgcaacaata gggaattatt attctcgata
    81301 atatcagcga attccttctt atcctcaagg ttatcggtcg aggcgaggat attagagaaa
    81361 cctacgatcg cattcaacgg tgtacgtatc tcatggctca tattagctaa aaacgcagat
    81421 ttcaatttat tcgactcctc cgccttatcc ctagccattc gaaggtcatg ttccaattgc
    81481 ttacgctcgg taatagatat cgtagacccg atcaacgctt tcggtttacc ggaagcatca
    81541 tattcgacca ttacctgtat ctcctcccac tcatggcgat cttctcccgg aatcaaccgc
    81601 tccagacaat attcttttcg tactttcttt attttcccat tacacaaatc atcgaaagcc
    81661 ttttccacgc aagccctgaa agacgggtgt atcttgctga aatattcctt caacgaaacc
    81721 tcatgggtat gcacctctgc tgtctctata ttatctcccg gatgtacttt cgactcatag
    81781 ataatcttct cttcagccag attatatcgc cacggtaaaa gatctgccgc ctctaacgcc
    81841 atagccagct tatgattcat ggctttcaaa tgcgtctgga atttatggat atccgtaata
    81901 tcaataaaaa acgcatcaac cacattctct tccgaggtag gcatgatgat aatcgtatag
    81961 taaagccctg tcggctcaaa ataatactca taagtgaagg attttccact ctctaaaacc
    82021 gtaggcactg ccgatagaag caaaggataa ctcccgccaa tcaaatttgc gatctctttt
    82081 ccacgcttat ttaccacaaa atctttagga gcgattttct cctcgaaagc atggttcaca
    82141 tctaaaacct gcacatcgat ttgcgtacct tctcgaatca gtcgctgccg tatataaggt
    82201 aacggcatat tattaaataa atcacggtaa cgggacaata acctcaactc tacttccttc
    82261 atcttttgct tagaacgata cacgtaatgc cacgctaaaa acacgactac cagaaagaat
    82321 atcagaaagc ctaacagttg catccaatat ttttccaaga aagagggagg cgcattcaag
    82381 tagatcgcat cacgcgggaa attatcttca ttagatatcg cacttatcaa cgaagcataa
    82441 ttcaaatatt tatgaggatc atttaccgtc gaaaccggga tcttgcccat atcttcaccg
    82501 ttataaactt gttgtagcaa ggggattaga gcagtctcaa tcgttttagc gctattataa
    82561 tatccaccaa tcgtatatcc ttcttccaca cccatatcat ataaagaaaa aacaggatgc
    82621 ctagaaatac cgtttatacc ttgatataaa gtactatata ataacgagtg attcaagaaa
    82681 ggtttctcgg taatccacga gtaatacatc acggctgtcg ctcgatgcgg atctttctcc
    82741 gacagaaccg ccaataaact atccatggag caagaaccct ccgtataaaa atccactttc
    82801 ccctcaggga aagaagtttc catatgtttc tccatctcat cccggagcca tgtggaaaca
    82861 taacgtctgt cggatatgaa aatcagacgt ttcaaacccg ggattaattc cttcaccaag
    82921 tcgatcgaac ctttaacata ataagggata accaatcccg tagcgttata ccccttaacc
    82981 gcctcttgta aaggaatcac cctatcagag gaatgccgct gattaaaata acattcattt
    83041 tctgccattt cccccgtctc cgaacagacc agagtgggaa tatcccccca tttctcccgg
    83101 atcttatccc gcataaaagc ccatccattt acgcctaagt agataattcc atccggcttc
    83161 ttcttgttag cttcaaagaa gacctcttgt ttctctttta atttctctgg cgtatcaacc
    83221 aacatcacgc ttatatgatc tatccggaga gtgtactcct ccggggtagc gaacttcgag
    83281 atcatgttta ataaattacc agaccaacgt tcgccatcca catatgaatt tatcaccaat
    83341 acatacgatt cctctttgac cggatatgaa gaactcccat aagccggagt cggcataccg
    83401 gctatcaagc ataaaatcaa tccaaaataa agtattattg cctttaaatt tataatattt
    83461 cgtatcattc cctacattcc tctattgcag ttgtaaagac aaagatattc cttaattatc
    83521 aactaatctt atcaaactcg tttttttatc aagttttggt gtcaaattca cgtttcttac
    83581 aaactaaagg cttttttaat cgggattatt cggctattta ccgatactcg tatagaaatc
    83641 agcggtattt acttgtgtat agaatgacga acccgtacat ttgataaaaa acaaaaaatg
    83701 gaacttatgg atatgaaaga ttatgacatc gattttaaag agaagaggac aaacgggtat
    83761 ctgatcgcta ccttatttat cattgtcggt atattatttt tactgcggaa tctaggaatg
    83821 atagatccat ctttatttga cttgcttgta tcttggccga tgctgcttgt cgtgtcgggc
    83881 atctttatga ttttccaccg taatccggta ggaggtatgc tcctcgtggg cgtgggagtc
    83941 tatttccttt tcccgcagtt aaattggatc acgaacgatt tcttacgtat atattggccg
    84001 ttaggattaa tcctgttagg attggtcatc atgctgaagc ggaaagattc tatccgcacg
    84061 aaaaagcata aacgtccctt taaccatccc cctttcgggc acagaaagcc taacgatgag
    84121 atcaactacg agacagataa cggtttcgta gcggttgaca ccactttcaa ctcggtaagg
    84181 cacatcgtac tggaccccgt attcaagggg gcggacatag acgtatcttt cggcaacgtg
    84241 attcttgatc ttaaaaaaac aacattagag gctgatgaaa ccatcataaa catagatagc
    84301 tccttcagcg gcgtagtaat atacgttcct aaaggatggc tggttcgtct aaaggttgat
    84361 tccttcttgg ctggatgcca agacatgagg gacctgacag aaacaaccga catgacgcac
    84421 acgttatata tatgtggaga cttgtcgttc agcggccttg aactaagaga ctaaactcat
    84481 catgcaagaa catcctatta caacatccat attacataaa gggctgggaa gcctattatt
    84541 acttttagcc atagcgatcc aatgcgcatt attaactctt tatggcgatc ttccgttgag
    84601 catcactttg gtcgatagct tactttccat cgcattgttc gccgtagcgg gatattatct
    84661 ttggtatgta caatgtacgt tacatatcat gcaagcacga gtggctttcg ccgtactcgt
    84721 acaaatcgct tgcatagccg gatgctcgat cttgctacaa atattcggat tggaagattg
    84781 ggaggaattc tcgatcacga ttccttttcg attcctgttc ggcctaatgg catggatcat
    84841 tctatcccaa tggtatgcca gccgggaaag aaagagtgag gcggaaccta tcgtgagaca
    84901 aatggaggaa aagacggcac ctcccccgac taccgttccg gaggagattc tagatcgtat
    84961 atccgtaaaa gacgggacac gtattcatat catcccgata aaagagatat tctatttgca
    85021 agcatgtggc gactatgtga ccttattcac cacttccggt cagcacgtaa aggagcaaac
    85081 catgaagtat ttcgagcgaa gccttccttc tccggagttc gttcgtatac atcgctctta
    85141 tatcgttaat acggaacaga tattgcgagt agaactattc ggaaaagaaa cctatcaagt
    85201 acgattaaag gatggaacct atcttcgtgc cagtagcgct ggctataagc tactcaaaga
    85261 acgtctttcc ctttagcagt cctatgaaag ggatctaatc atcgttaaaa ttagaagatt
    85321 ttgattgtaa tatatagagc tttatgttgt gtaacacttt ttagcaagca tcgacatgtt
    85381 acttaacata tattagttgc aaaagacttg acaaatggtc ttgacgaacg tatctttgca
    85441 tcgtggtttt ttcataatag tattagattt aaggttaaca aagtttggtt agggcttgtc
    85501 gtgagacagg ctttaattgt ttatagaggt ttgcttccct agatttacat ataactataa
    85561 aaaaacggcc acccctaaaa agaggcggcc gtaattattc ttaatgaaag aacctactct
    85621 ttgacaatcc ttgtaacttc caaatcaaag atcaaagtcg tataaggctt tattatgaca
    85681 cttcccgaag cactccttcc agccgaaccg tatcccatct gttgaggaat ccaaatctcc
    85741 caacgatctc ctgggtgcat attctgtaac gctgtagcaa aaccatctac catctcagaa
    85801 acagtaagct cggcaggggc acctgcctca aacgatttat catcaaaaac cgttccatca
    85861 ataaacgtcc ctttataata acattccacc ttgctcgtat aataaatcgg ctccttactc
    85921 tccccagtct tcaagacctt gtaaaggata aatccggcat tactttgaga actcaattgc
    85981 tcgaaacccg gaaccagcat ctgggcttga aaagcctcct cattctggac cttccaaacc
    86041 tcatccacct ctagtgcctc atcatcatcc ccacaagagg tgatcatgag cacgcaaaac
    86101 aacatcaacg caatatgcca gtacttcttc attcgtttac tctattacct ttttcaataa
    86161 attcttcatg ctcaccttct ccgtgataat atcgtgaagc ttatcgatgc ttacgcgctc
    86221 ttgctccatc gtgtcacgga aacggatcgt tacgcaatta tccttcaagg tgtcatggtc
    86281 taccgtaata caatacgggg taccgatcgc atcctgacgg cgataacgct taccaataga
    86341 atccttctcg tcgtattggc aacggaagtc gaaacgcaac atatttataa tctcctcagc
    86401 tttctcgggc aggccatctt tcttcaccaa tggcaatacg gccaacttga tcggagccaa
    86461 ggctgcgggc aacttcaata ccacacggct ctcgccattc gccaacgtct cctcgcagta
    86521 agaacccgcc atgatgctca agaacacacg gtctacaccg atcgaggtct cgattacata
    86581 cggagtgtaa ctctggttca actccggatc gaaatattgg atctttttac cggaaaactt
    86641 ctcatgctga ctcaagtcga aattcgtacg gctatgtata ccctccactt ccttgaatcc
    86701 gaacggcatc tcgaactcga tatccgtagc ggcgttagcg tagtgagcca acttctcatg
    86761 atcgtgataa cgatacttct gatctcccaa gccaagagct tgatgccatt ttaagcgagt
    86821 agacttccat ttcttgaacc actcgatctc ctcacccgga cgaacgaaga attgcatctc
    86881 catttgctcg aactcgcgca tacggaagat aaactgacga gccacgatct cattacggaa
    86941 cgccttaccg atctgggcga taccgaacgg gatcttcata cggccagtct tctgcacatt
    87001 caagaagttc acgaaaatac cttgagccgt ctccggacga agataaatct tagtcgctcc
    87061 atcagcggta gaacccatat ccgtagagaa catcaagtta aactggcgaa cctccgtcca
    87121 gttacgagtt ccggaaatcg ggcaaacgat ctcgcaatcc aagatcaatt ggcgaagatc
    87181 ctcgaagtta gactcgttca tcgccttact ataacgctca tgaatctcat tccatttcgc
    87241 ttgatgctcc aatacacgag gattcgtctc acggaattta gcctcatcga aagcgtcacc
    87301 gaatttcttt gcggctttcg ccacttcctt atttattttc tcctcgatct tgcccaaatg
    87361 gtcctcgatc aaaacgtccg cacggtaacg tttcttcgag tccttgttat cgatcaacgg
    87421 atcattaaaa gcgtcaacat ggccggaagc tttccagata gtagggtgca taaaaatagc
    87481 ggaatcaata cccactacat tctcatgcag caaagtcatg ctatcccacc aatatttctt
    87541 tatattgttc tttaactcaa caccatactg gccataatcg tataccgctc ccaaaccgtc
    87601 ataaatctct gaggaaggaa atacgaaacc atactcctta cagtgtgaaa ctagtttctt
    87661 aaatacatct tcttgtgcca taatctaata atttgccaat tttgttaata tgccaatgtg
    87721 ccaatgataa gtccatcgga gacccgcctg agtggcacat tagcacatgg tctcctttat
    87781 gcggctacaa agtaaatgat tttttccgta actatagaaa gttttgtata tttacgacgt
    87841 aaatcgttag tgtttgcgca aacagtataa tttaaacaag ataataccat gaaatcagaa
    87901 gaaatctcac gccgctcgtt ccttaagcga gcgctagcct tatcggcagt atcggccatc
    87961 ccgtcgttct ggacacccgc ccacggacgt gttctaccta cttccccgct aatcagcgct
    88021 aatgaccggg taaacatcgc attcatcggc atcggacaac gagggggcga gatcgccaag
    88081 gaattgtata acacaggtct gtgtaacgtg gtagctctct gcgacgtgga catgggagcc
    88141 cctcacacgc aagagattat caacatgttc ccgaaagcgg cccgttttca agatttccgc
    88201 acgatgttcg accggatggc ggataagatc gatgccgtaa gcgtaggcgt gccggatcat
    88261 tcccacttcc cgatcacgat cgaggcgatg gcgcacggca aacatgtata tgtagagaaa
    88321 ccgatggccc gcacgttcca agaaatagag atcatgatgc gtggagcgaa gaaatacggc
    88381 gttgtcaccc aaatgggtaa ccaaggacat tccgaggcga actatttcca attcaaggca
    88441 tggaaagagg ccggtattat caaggatgtt accgccatta ccgcccatat gaataatccg
    88501 cgtcgctggc acggatggaa cccgaatatt aggcatatgc ctatgggaga accggttccc
    88561 gagacgatgg attgggacac atggatcggc gtagcccaat atcatgatta caaccatgac
    88621 taccatttgg gacaatggcg ttgttggtac gacttcggaa tgggtgtctt aggagactgg
    88681 ggagcgcata ttttggatac ggcacatgaa ttcctagatt taggattgcc tacagaaata
    88741 aatccgcttt atttgaaaga ccataacccg ttcttcttcc cgatgtcatc cacccttttg
    88801 tttaaattcc cggaaagagg gaatatgccg gccgtggata tcacttggta cgatggactg
    88861 gacaatatcc cctctgtccc ggaaggttac ggtgtttccg aacttgaccc gaatatcccg
    88921 accgtagccg gcggcaagat acaaccggcg aagttgaacc cgggcaagga aatctactcg
    88981 aaagaattaa ccttcaaggg tggttctcat ggaagtacct tatctatcat cccggatgag
    89041 aaagcgaaag agatggaatc ccgcttaccg gaagtgccga aaagcccgtc taaccatttc
    89101 gcaaacttcc tgctcagttg tatgggtaag gagaaaaccc gctcaccgtt ctctatcgcc
    89161 ggcccattaa gtcaggtatt ctgtctcggc gtattaagcc agcgcttgaa ccgcaagctc
    89221 gtcttcgacc gtgacacgaa acagatcacg aacgatccgg aggcgaataa gatgctatgt
    89281 ggagtaccgc ctcgcaaagg atgggaacaa tattatacca tttaattgaa acatggagaa
    89341 ttgaaagtta ttcgctcatc gctttaactt tcaattctct catatagttt ataagcctat
    89401 ttgctacaac atctacaact atccctgcat tcatctggtc ttaggatgat taactaatgg
    89461 tggtagataa agaacatcta caattatcta gctctatcta ccactattta ccgctattta
    89521 ccacttttcc atcacctaac acaacgcttc tccacactca ccatatagca ttatccgatc
    89581 tcctttcaac acggataaaa tattaacatc tagccatttg tagtttttta acctaaaaaa
    89641 caaaagtttt attataggaa aacaaaagtt taataagcgg aaaacttttg tttctctata
    89701 gggaaactaa agtttcctca gtatgaaact tttgttacct ctaagagaaa tgtcttttgc
    89761 ttttaatccc gacgctacgc tctgcatttt ttgttatatt tatggcaaat atagaaaacc
    89821 ataagaacta aaagaatttt caaattaccg aaggaaaagt acaaggagtg agaacaacta
    89881 cggaaggggt cttattgtat aagggtattt catgaagacc ggaaatccga acgaacaagg
    89941 attggacgaa taggcaccct atacgaagga aaaaacattc gtgatgacat tccatatcga
    90001 ataaagtcat cacgaacgcc ttcaaatata ctcataggac tccgagaaac tcgactggga
    90061 gctagaagaa gctaattctt cagagactaa ttgaagcaga ttgccattct gatcatagga
    90121 cttcgtgatc cgacgaagct ctatggattc tttttctgtt ggaaggtcgg cataaaccat
    90181 gatctccatg ttcaatccgt tctcattacg gtactcgcta tatcggagaa cctcggacgt
    90241 ttcgggatca cgaatcgttt cttttgtcaa caaccctgtc tcatcgtact catagtccgt
    90301 ataagtaagc ttccggccga gtttgtcgta ctcaactttc cgttccagaa gattattctt
    90361 ataagaaaag actgtcacct tgctcttgcc aataaccgga tattcagtaa tcccctttat
    90421 tttccggcct tgttcatcat acttataatg aagcgtagac aaattatgat acgtctgatc
    90481 taggtttctg ttgaagtaaa cttcttacgc caaaagacac cgaatattcg tcagattcgt
    90541 atcctatgag tgatttgccg ttaaagcttg aacttatacc caaccgtcag actcatcgta
    90601 ttgtaattgg caccgacact tcttacctca tacagagaga aattatcgcc atcgatctta
    90661 tagttaccgc cctcatcacc tagagagaga tcatacccca gattcatcac ccagttattc
    90721 acctctatac caaaagaagt tgtcaatccc caatcaaaag aattcacgtc tcgaaatgga
    90781 tgatcggcgt tttcagcctc atcatatccc gaatggccat aaccataact ataccctagg
    90841 ccagtagatt tgacatattt accaagcgcc tgcggctcct tcgaataccc catcgtaaac
    90901 gaagatcccc aattcgtatc attcttgaca gatacaccgg catacatacc gaccgctaaa
    90961 tgcatacgta cctctttcga cactttccat gagaaatcag ccatcacggg caattgcaaa
    91021 aaatgttgcg tgataccacc ggtcatcatc tctttcaaga catacgtagc agactccgtc
    91081 gttctcggat aatctcccaa cgaataccct ctattcgcat aatatagacc ggatttcaat
    91141 ccaatccatc ccggttcaaa ctggtaagat acaccaacgc ctaccttaac ccccgcacgc
    91201 cagctagagc ccattccaac acgattaacc gcagcaaatc caccctccgg agtaatcccc
    91261 cagcgtgatt gagcgctcac catcaagcca ctcaaagcgc ataacacaaa taaaatcagc
    91321 ttcttcatat catattcttt tatatgtaaa tatcaattgt tattgataag acaaaagatt
    91381 ctgaaaaacc cctaccacct aaatatttat tttataaaat ctctttattt aacgcaaact
    91441 cactctcgta aaagcctcat tcttataaaa actgccgaat atttgctata tttacaccct
    91501 gttagcaatt tggcgtaata gcgttgtgta gaaagaactg gattttatga gaccggaaga
    91561 taaagaagac gattatatcg aggataagga aaacgaggaa attgaggata taaatagtga
    91621 tacccaagat aacgagacta cggaggaaga ggcgaatacc cattccgact ataaagtccc
    91681 ggggaaaggg gatacacgtg tcacgaccta tcatttgtct gggatgtacc aaaactggtt
    91741 cctagactac gcttcttatg tgatcttgga acgggccgtt ccgcatatca acgatggact
    91801 gaaacccgta caacgacgta tcctgcactc catgagaagg ttggatgacg ggcggtataa
    91861 caaggttgcg aatatcgtag gtcatacgat gcagttccac cctcacggag acgcctctat
    91921 cggagatgcc ttggtgcaat tgggacaaaa ggatctgttg atcgattgcc aaggaaactg
    91981 gggtaatatc ctgacgggag acggagccgc cgctcctcgt tatatagagg ctcgcctttc
    92041 caagtttgcc ttggagaccg tattcaatcc caagacaacc ctttggcagc tttcttacga
    92101 cgggcgtaat aaggaaccgg ttaccttacc ggtaaaattc cctttattgc tggcacaggg
    92161 cgtggaaggt atcgccgtag gcctgtcttc caagatactc cctcataatt tcaatgagtt
    92221 attagatgct tccatcgcct atctacgggg agaggaattc gcgttatatc cggatttcca
    92281 gacaggaggc tctatcgaca tagccaaata taatgatgga gaacggggtg gatcggtgaa
    92341 agtccgtgcg aaaatcggca agctcgataa taagacattg gtgatctcgg agatcccgta
    92401 tggaaaaaca acctctaccg tgatcgagtc catcctaaaa gcgaacgata aaggaaagat
    92461 caagatcaag aaggtagacg ataataccgc caaggatgta gagatcttgg tgcatctcgc
    92521 tccgggggtc tcttcagaca agaccatcga tgctttatac gcctttacgg attgtgagat
    92581 cagtatctcc ccaaactgtt gcgtgatcaa ggaggacaag ccgcatttcc ttacggtcag
    92641 cgatgtgctt cgccactcta cggatcgtac gctggagctg ttacgggaag agctcaagat
    92701 ccagaaacaa gagcaggagg aggccctgtt cttcgcctcc cttgaaaaga tatttatcga
    92761 ggaacgtatt tataaagacc cggagttcga gaacgccaag aacatggacg aggcgatatc
    92821 ccatatcgac cttcgtttag agccgttcaa gccccgattt atccgtgagg ttacccggga
    92881 cgatatcctg aaactcatgg agatcaagat gggacgtatc ttaaagttca actccgacaa
    92941 gagtaacgag ttcattgccc agaccttgga acaaatcgcc aagatcaacg ataagctgga
    93001 acatatcgtc gactatacca tcgattggtt taccatgctg aaagagaaat acggcaaggc
    93061 ttaccctcgc cataccgtga tacgcaattt cgacacgatc gaggcgacca aggtcgtaga
    93121 ggcgaacgag aaattgtata tcaaccgtca agaaggtttc atcggcatgg gactgaaaaa
    93181 ggacgagttc atatgtaact gctcggatat agacgatgtc attatcttct atcgcaacgg
    93241 tacttataag atcgtcaagg tagcggataa gatctttatc ggtaaggata ttctatatgt
    93301 caacgtattt aagcgcaatg acaaccggac gatttacaac gttatatacc gggacggtaa
    93361 gttcggatat aattacatca aacgcttcgc tgtcacgggc gctacacgcg accgggaata
    93421 cgacctgacc aaaggaacgg aaaactcccg tgtcctttac ttcagcgcga acccgaacgg
    93481 agaggcggag accgtcaagg taatcctgaa acccaaaccc cggcagaaac tactcgtctt
    93541 cgagaagaac ttcagcgaga tagccattaa gggacggggt tctcaaggta atatcctgac
    93601 gaaagcggaa gtgcacaaga tcagcctcaa gcagaaaggc tcttccacct tgggaggccg
    93661 ggaagtatgg ttcgactggg acgtactccg gttaaattac gatgggcggg gagaagagct
    93721 aggagagttc cacagcaacg atcaaatatt agtgattttg ccgaacggtg atttctacgt
    93781 cacgaatttc gaccttagca atcactacga gtccaatatc atggtcatcg agaaatacga
    93841 gccgagcaag atatggactg ccgtattata cgacgcagat cagaaatatt attatatcaa
    93901 acgattcctg ctggaggtaa acacccggaa gcagaatttc ctaggagaga atccgaagaa
    93961 ccgcttgatg ttgcttacgg atgaggtcta tcctcgtatc gaggtgatct tcggaggcca
    94021 cgacgccttc cgggaggctc tcatcctcga tgccgacgaa tttatcgcgg tgaaaggctt
    94081 caaagccaaa ggtaaacgaa tctctacatt tgaggtcgag acaatcaatg agctggaacc
    94141 gaatcgcttc gtcccttccg aaaacgcatc ggaatcagac gataccgaag gcaatgagga
    94201 gggaaacgac actgacgacg ggcagagtac cacggatatt atcgatgaaa ttacgggaca
    94261 gatgaaattg tttgacgaat aacctatgaa agctatcacc tgtttgattg gtttgttcct
    94321 gctgtttctc gcgtcaccgg ccaaggccca gtccgatgga gacgagatcc cttggtctat
    94381 caacagcggg accatggtcg gtataggaag ctacaaccta atggacacct atttatctcc
    94441 cagcatggaa gataagaaat atacaggccc cggattacgg gtaatgaatg aacggatgaa
    94501 gagggtccga ctggcaaact atcgggtatc cagacagcaa atcataagcg tcgatctggc
    94561 tagcacggat aatgctgcct ctaccgctac ggatttcgcg ggctttatcg attatacgtt
    94621 gggttactat tatcatttgc ccacgctatt gccggatcta aagcttctgg cgggtggtgc
    94681 cgtgcatggc atgggtggtt ttatatacaa tacccgtaac ggaaataacc cggcctcggc
    94741 gaaagcggat atcgatttga acatctctgc catggcgatc tataagttac gcgtcaagga
    94801 atatcccatg acgctacgct accagttcac gatccccttc gccggtgttt tattctcccc
    94861 ccattacggg caatcgtatt acgagatctt caacctaggg aatgcctcgg gagtggtgca
    94921 attcaattcc ttccataata aattcgccat gaagaacttt ttcacggtag atttcccggt
    94981 ttgtaatttt acgatacggg caggttacct aaacagctct taccgtacag atgtcaatgg
    95041 gatacagtct catataatct ctcactcttt tatgatcggc ctcgtgaaag aatttatctc
    95101 tttcggagga aaacgcctaa agaataccca gcggttcaga agcgcttatt attaaaagga
    95161 aatcaaatga aacgatacct tatatatata tgtatatctc tcggattcct gtttaccgga
    95221 tgtgagaaat cggacgaata cgtggcctcc ccacaggaga actttgaggc gctttggaaa
    95281 atattggatg agaattactg cttcttcgaa tacaaggaca ttgattggaa cgaggttcac
    95341 gaccgttata agacgcagat aagcgatacg atgaaccaat acgtcctatt tgacgtatta
    95401 ggcgatatgc taaacgagct gaaagacggg cataccaatt tgatatccac cttcaatatg
    95461 tcccgctatt gggattggta tctcgattat ccggataatt tcgactcgga catacaagag
    95521 aattatctcg gaaggaacta ctcgatcgcc ggaggactta aatacacgac attgagtgac
    95581 gggcagatcg ggtatattta ctacggtagc ttttccagtt cggccggcga aagcggtttg
    95641 gatcacatat tctatcaatt caaggattgc aaaggtttga tcttcgatat ccgggataat
    95701 ggcggtggca tgttatcaaa cgccgatcgc atcgcttccc gtttcttgga ggaaaagata
    95761 ctgaccggct atatccaaca taagacgggt aaagggcacg atgacttttc cgaaccttat
    95821 cccctttatc tctcaccttc cgagcgtatc cgctggttac gccctgttgt ggtcttaacg
    95881 aatcgtcatt gctacagcgc cgccaacgat ttcgtgcaga aagtacgcat gatgccttat
    95941 gtaacgacga tgggagatcg caccggaggc ggtagtggct tcccctttaa ctccgagttg
    96001 cccaacggct ggggtgtccg tttctccgcg tctcccatgc tagatgtaaa caaacagcat
    96061 acggaattcg gtatcgatcc tacatataag gtttctatga cccaagaaga tatcgagaaa
    96121 ggtaaagata cgattataga ggcggcgatc acccacctct tgtccgagac cgagaagaaa
    96181 taaggtttcg ctaaaaaaac aacgcaaata tttgcaagtt tataaaaaag cattaccttt
    96241 gcacacgatt ccaatgcggc tgtggtgtaa ttggtagcca cgtcagactt aggatctgat
    96301 gcttcacggc gtgggggttc gagtcccttc agccgcacaa atccagaaat ccttgtaagt
    96361 tcgcttacaa ggatttttta gtatggataa acctcctcca tatatacaag cactgtgaag
    96421 atcaaggatt acaaacaaca tccaaactgt taattttaga agattttatg cctattctgt
    96481 atagtttcaa attcaaaaac attttttata ccgggcagac atgttgttta acacaagtta
    96541 tactcaaaac ccttgacaaa ggggctttac aagcttatct ttgcattgtg gttttttcat
    96601 aatagtatta gatttaaggt taacaaagtt tggttagggc ttgtcgtgag acaggcttta
    96661 attatttata ggggtttcat tcgtttatag atgcttcccg gcatcgattt tatctttcca
    96721 tccaattcca actcaaagag cagagaagat aattgatgta ccggaagatt caaggctacg
    96781 gacaattcat tgatatgaga ttcctttcgc atttccaaga acgacaagat ccgttcactc
    96841 tcctcgttct caggaaataa taattgggtt tggaccggta acgcatctgt cttttgagcg
    96901 acatcccaac gcatcgccat gattaaatcg tcagcgcaag tgatcaagcc tcctttattc
    96961 tgccggatta agccattaca tcctttagag ttgatatccg ttacccggcc cggaaaggca
    97021 tagacatccc ggccatacga gaaagcgata tccgccgtga tcaaagagcc tcctttctcc
    97081 gccgattcaa taacgatcgt ggcatccgcc agaccggcta cgatccggtt tcgccggata
    97141 aagttctgcc gatccggatt cgtcccgcta ggaaagtcgg tcaataaacc tccccgctcc
    97201 aacatctcga ccgccgtaga gcgatgcacg ggaggataga tacgatccaa accatgcgcc
    97261 aatacgccca ccgtgggcaa ttggttcttc aacgcattcc gatgagcgca aatatcgatg
    97321 ccatatgcga gtccgctaac gaccaataga tccgggaaaa tcacggacaa atcccgcaat
    97381 aaacgctcgg tcacttcctg cccataagcg gaggccctac gagtacccac aacgctgatg
    97441 atatgggcgg cgtttaaatc cgcgttcccc ttgaaataaa ataaaaccgg agcgtccggg
    97501 ca
//
LOCUS       DBMDTB010000003        83409 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_128_length_83409_cov_11.539768, whole genome shotgun sequence.
ACCESSION   DBMDTB010000003 DBMDTB010000000
VERSION     DBMDTB010000003.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 83409)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 83409)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..83409
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_128_length_83409_cov_11.539768"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(634..1274)
                     /locus_tag="ACZPB4_00875"
                     /pseudo
     CDS             complement(634..1274)
                     /locus_tag="ACZPB4_00875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005825818.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage integrase SAM-like domain-containing
                     protein"
     gene            complement(1545..1964)
                     /locus_tag="ACZPB4_00880"
                     /pseudo
     CDS             complement(1545..1964)
                     /locus_tag="ACZPB4_00880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867135.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4270 family protein"
     gene            2236..3237
                     /locus_tag="ACZPB4_00885"
     CDS             2236..3237
                     /locus_tag="ACZPB4_00885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Kelch repeat-containing protein"
                     /protein_id="HIR1096814.1"
                     /translation="MIHKRILVFLIAFLPVIISACSDDDDDDLIGKWYRVSDMDGLAR
                     NYASSFTIGNKGYLICGNDGKNRLSDCWEYDMERDTWTQKADFPGTARNSAVAMAVDE
                     KGYLGTGYDGTNYLNDFWEFNPTTNTWAQKADFPGSGRYGAVAFGVNGKAYIGCGYDG
                     NYLKDFYAFNPVANSWTQTISIGGTKRQGATSFVINGIAYVCCGQNNGEYVDDFWKFD
                     PSTESWTQLRDISDSSDEDYDDDYTITRTNGVAFVIDGAAYLTCGESGSLRSDTWKYY
                     PATDLWENVAKFKGTARTATASFSSGEKGFVVSGKSGTTQFDDIWEFHPNEYDDDEY"
     gene            3224..3577
                     /locus_tag="ACZPB4_00890"
     CDS             3224..3577
                     /locus_tag="ACZPB4_00890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4907 domain-containing protein"
                     /protein_id="HIR1096815.1"
                     /translation="MMNTKKGRAWFVPGLVVLPVLLFYLSFFRGEEMGSSPGRQLELQ
                     TFQSGDGWGYQIRMNGKVLIYQPTIPSIDTVIAFPDKESAENIGTLVLNKLAGNRNFS
                     VSREEIQHSLSYLGQ"
     gene            complement(3710..4993)
                     /gene="eno"
                     /locus_tag="ACZPB4_00895"
     CDS             complement(3710..4993)
                     /gene="eno"
                     /locus_tag="ACZPB4_00895"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000015 - phosphopyruvate hydratase
                     complex [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004634 - phosphopyruvate hydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HIR1096816.1"
                     /translation="MEIVKVVGREILDSRGNPTVEVDVHLASGAFGRAAVPSGASTGE
                     NEAIELRDGDKNRYGGKGVLRAVDNVNKVIAPAILGMSALNQREIDHKLLDLDGTKTK
                     SNLGANAMLGVSLAVAKAAANYLDLPLYRYIGGTNTYVLPVPMMNIINGGSHSDAPIA
                     FQEFMIRPVGAKSFREGLRMGAEVFHALKKVLHDRGLSTAVGDEGGFAPALDGTEDAL
                     NSIMAAIKAAGYEPGKDVTIAMDCAASEFYHDGVYDYTKFEGEKGAKRNAQQQVAYLS
                     ELVNKYPIDSIEDGMDENDWAGWQMLTSTLGGKCQLVGDDLFVTNVEFLKKGIEKGCA
                     NSILIKVNQIGTLSETLDAIEMAHRNGYTSVTSHRSGETEDATIADIAVATNSGQIKT
                     GSLSRSDRMAKYNQLLRIEEELGSLAVYGYKTYKK"
     gene            5209..5691
                     /locus_tag="ACZPB4_00900"
     CDS             5209..5691
                     /locus_tag="ACZPB4_00900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1096817.1"
                     /translation="MTLLDLFLLFGKGEFIYADTASVPPEYKACLCSSCEDHIDDNHH
                     TGYSFDQEDGEVIAKGLSTEPDNFLPQRLNLYNAFETKDYDNGIQQTSGFFNTPNGKF
                     IWQDYLYQDRLLNATQQYEPSLENLSKAVKLAEYYRYLGYFYYLKKIWTIQKYTGIRS
                     "
     gene            complement(5858..6343)
                     /gene="rplQ"
                     /locus_tag="ACZPB4_00905"
     CDS             complement(5858..6343)
                     /gene="rplQ"
                     /locus_tag="ACZPB4_00905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HIR1096818.1"
                     /translation="MRHNKKFNHLGRTNTHRDAMLSNMACSLIKHKRIFTTTAKAKAL
                     RKYVEPLITKSKEDTTHSRRVVFSNLQDKFAVTELFKEIAQKIGDRPGGYTRIIKTGN
                     RLGDNAAMCFIELVDYNENMLKDTAAKKAPKTRRSRKKATASVAEAPTAEAASEEKAA
                     E"
     gene            complement(6351..7343)
                     /locus_tag="ACZPB4_00910"
     CDS             complement(6351..7343)
                     /locus_tag="ACZPB4_00910"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018109216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed RNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HIR1096819.1"
                     /translation="MAILAFQKPDKVLMLEADNFFGKFEFRPLEPGYGITIGNALRRI
                     LLSSLEGFAITSIKIDGVDHEFGTIPGVIEDVTNIILNLKQVRFKHIVDDIENEKVSI
                     TVSGSEVFKAGDIGKQLTGFEILNPDLVICRLDPTASFQIELTINKGRGYVPADENRD
                     PNADIHVIAIDSIFTPIRNVKYSIENFRVEQKTDYEKLVLEIATDGSIHPKEALKEAA
                     KILIHHFMLFSDEKIAIETADTEGNEEFDEEVLHMRQLLKSKLADMDLSVRALNCLKA
                     ADVETLGELVKFNKNDLLKFRNFGKKSLTELDELLESLNLSFGMDITKYKLDKE"
     gene            complement(7356..7961)
                     /gene="rpsD"
                     /locus_tag="ACZPB4_00915"
     CDS             complement(7356..7961)
                     /gene="rpsD"
                     /locus_tag="ACZPB4_00915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018667875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HIR1096820.1"
                     /translation="MARYTGPRTRIARKFGEAIFGADKVLSKKNYPPGQHGNSRKRKT
                     SEYGIQLREKQKAKYTYGVLEKQFRNLFEKASRSKGITGEVLLQLLEGRLDNVVYRLG
                     IAPTRAAARQLVSHRHITVDGSVVNIPSYSVKPGQVIGVREKSKSMEVIADALSGFNH
                     SKYPWIEWDQSSMSGKLLHLPERADIPENIKEQLIVELYSK"
     gene            complement(8085..8474)
                     /gene="rpsK"
                     /locus_tag="ACZPB4_00920"
     CDS             complement(8085..8474)
                     /gene="rpsK"
                     /locus_tag="ACZPB4_00920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005634781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HIR1096821.1"
                     /translation="MAKKTVAAKKRNVKVDAYGQAHIHSSFNNIIVSLANSEGQVISW
                     SSAGKMGFRSSKKNTPYAAQMAAQDCAKVAYDLGLRKVKVFVKGPGNGRESAIRTIHG
                     AGIEVTEIVDVTPLPHNGCRPPKKRRV"
     gene            complement(8486..8866)
                     /gene="rpsM"
                     /locus_tag="ACZPB4_00925"
     CDS             complement(8486..8866)
                     /gene="rpsM"
                     /locus_tag="ACZPB4_00925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009125149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HIR1096822.1"
                     /translation="MAIRIVGVDLPQNKRGEIALTYIYGIGRSAAKSVLDKAGVDRDI
                     KVKDWTDDQAAKVREVIGAEYKVEGDLRSEVQLNIKRLMDIGCYRGVRHRVGLPLRGQ
                     STKNNARTRKGKKKTVANKKKATK"
     gene            complement(8902..9018)
                     /gene="ykgO"
                     /locus_tag="ACZPB4_00930"
     CDS             complement(8902..9018)
                     /gene="ykgO"
                     /locus_tag="ACZPB4_00930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014790280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L36"
                     /protein_id="HIR1096823.1"
                     /translation="MKVRASLKKRTPECKIVRRKGRLYVINKKNPKYKQRQG"
     gene            complement(9032..9250)
                     /gene="infA"
                     /locus_tag="ACZPB4_00935"
     CDS             complement(9032..9250)
                     /gene="infA"
                     /locus_tag="ACZPB4_00935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018109212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HIR1096824.1"
                     /translation="MAKQSAIEKDGVIVEALSNAMFRVELENGHEITAHISGKMRMHY
                     IKILPGDKVRVEMSPYDLSKGRIAFRYK"
     gene            complement(9261..10046)
                     /gene="map"
                     /locus_tag="ACZPB4_00940"
     CDS             complement(9261..10046)
                     /gene="map"
                     /locus_tag="ACZPB4_00940"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008149918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HIR1096825.1"
                     /translation="MIYLKTDEEIELMREANQLVGKTLGEVAKHIVPGVSTLQLDKIA
                     EEFIRDNGAVPAFLGYGGFPNSICASVNDQVVHGIPSSKMILKEGDVISVDCGTILNG
                     FVGDSAYTFCVGEVAPEVKKLLKATKDSLYLGIQCAVEGHRLGDISNAIQTYCESQGY
                     SVVRELVGHGIGRKMHEEPEVPNYGRRGCGPLLRNGMCICIEPMINMGSKNVAFEKDG
                     WTVRTKDRKPSAHFEHCIAIRPDGPQILSSFKFLEEVLGENAI"
     gene            complement(10051..11391)
                     /gene="secY"
                     /locus_tag="ACZPB4_00945"
     CDS             complement(10051..11391)
                     /gene="secY"
                     /locus_tag="ACZPB4_00945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HIR1096826.1"
                     /translation="MRAVETIKNIWKIEDLRNRILTTLLLVAIYRFGTYVVLPGIDPK
                     ALTALQEQTRGGLLALLDMFSGGAFSNASIFALGIMPYISASIVMQLLAIAVPSFQKL
                     QREGESGRRKINQWTRYLTIAILLFQGPTYLVNLSVQLKAAGAALPGGIWFTISSTII
                     LAAGSMFILWLGERITDKGVGNGISFIILVGIIARLPHSLFQEFVSRTSEKTGGLVMF
                     LFEMLFLLLVIAGAILLVQGTRKVPVQYAKRIIGNKQYGGARQYIPLKVNAANVMPII
                     FAQAIMFIPISIVGFSSTGEQSGFWAAFMDNTGFWYNFVFAVLIILFTYFYTAITINP
                     TQMSDDLKRNNGFIPGVKPGKNTKDYLDTIMDRITLPGAFFLALVAIMPAFARIAGVS
                     MEFSQFFGGTSLLILVGVVLDTLQQVESHLLMRHYDGLLKSGRIKGRTGSVAAY"
     gene            complement(11395..11841)
                     /gene="rplO"
                     /locus_tag="ACZPB4_00950"
     CDS             complement(11395..11841)
                     /gene="rplO"
                     /locus_tag="ACZPB4_00950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018667878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HIR1096827.1"
                     /translation="MNLSNLKPAEGSTKTRKRIGRGPGSGLGGTSTRGHKGAKSRSGY
                     KNKIGFEGGQMPIQRRLPKFGFKNINRVEYKAINIDTLQQMAEAKQLTKIGINELMEA
                     GFISSSQVVKILGNGSLTAKLEVEAHAFSKSAEAAIQAAGGTVVKL"
     gene            complement(11871..12047)
                     /gene="rpmD"
                     /locus_tag="ACZPB4_00955"
     CDS             complement(11871..12047)
                     /gene="rpmD"
                     /locus_tag="ACZPB4_00955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007838934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HIR1096828.1"
                     /translation="MATIKVKQVKSRIKCPKDQKRTLDALGLRKMNQIVEHEANPAIL
                     GMVEKVKHLVSVEK"
     gene            complement(12066..12584)
                     /gene="rpsE"
                     /locus_tag="ACZPB4_00960"
     CDS             complement(12066..12584)
                     /gene="rpsE"
                     /locus_tag="ACZPB4_00960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004583581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HIR1096829.1"
                     /translation="MKMANNRVKSTNDLELKDRLVAINRVTKVTKGGRTFSFAAIVVV
                     GNEDGIVGWGLGKAGEVTTAIAKGVEAAKKNLIKVPVHKGTIPHEQLAKFGGAQVLIR
                     PASHGTGVKAGGAMRAVLESVGITDVLAKSKGSSNPHNLVKATIAALGELRSPFDVAQ
                     NRGVAVEKVFRG"
     gene            complement(12584..12928)
                     /gene="rplR"
                     /locus_tag="ACZPB4_00965"
     CDS             complement(12584..12928)
                     /gene="rplR"
                     /locus_tag="ACZPB4_00965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005656518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HIR1096830.1"
                     /translation="MTTKLERRLKIKAGVRGKISGTTERPRLTVFRSNKQIYAQVIDD
                     TTGKTLAAASSLKLDVKAPKKEIAAKVGELIAKGAQEAGVQTVVFDRNGYLYHGRIKE
                     LADAARNGGLKF"
     gene            complement(12950..13501)
                     /gene="rplF"
                     /locus_tag="ACZPB4_00970"
     CDS             complement(12950..13501)
                     /gene="rplF"
                     /locus_tag="ACZPB4_00970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009859534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HIR1096831.1"
                     /translation="MSRIGKLPIHVPAGVTVTIKDNVVTVKGPKGELVQEVNPDINVT
                     LEDGVIHLTRPTDDKNHRALHGLYRSLINNMVVGCSEGYKKELELVGVGYRVSNTGQL
                     LDLSLGYTHNIYLQLPKEVKVETKSERNKNPLIILESADKQLLGQICAKIRSFRMPEP
                     YKGKGIKFVGEEIRRKSGKSAGK"
     gene            complement(13518..13913)
                     /gene="rpsH"
                     /locus_tag="ACZPB4_00975"
     CDS             complement(13518..13913)
                     /gene="rpsH"
                     /locus_tag="ACZPB4_00975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005782213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HIR1096832.1"
                     /translation="MTDPIADYLTRLRNAIKAKHRVVEVPASNLKKEITKILFDKGYI
                     LNFKFVEDGPQGTIKIALKYDLVNKVNAIKKLERVSTPGLRKYTGYKEMPRVLNGLGI
                     AVLSTSKGVMTDKEARDLKIGGEVLCYVY"
     gene            complement(13972..14241)
                     /gene="rpsN"
                     /locus_tag="ACZPB4_00980"
     CDS             complement(13972..14241)
                     /gene="rpsN"
                     /locus_tag="ACZPB4_00980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004296337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HIR1096833.1"
                     /translation="MAKESMKAREVKRAKLVAKYAAKRAQLKAEGNYEALQALPKNAS
                     PVRLHNRCKITGRPKGYVRQFGISRIQLREMASNGLIPGVKKASW"
     gene            complement(14248..14805)
                     /gene="rplE"
                     /locus_tag="ACZPB4_00985"
     CDS             complement(14248..14805)
                     /gene="rplE"
                     /locus_tag="ACZPB4_00985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005853986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HIR1096834.1"
                     /translation="MSNTASLKKEYQDRIVPALTKEFGYKSVMQVPVLKKIVINQGLG
                     MATADKKIIDIAISELSTITGQKAVATVSKKDISNFKLRKKMPIGVMVTLRREQMYEF
                     LERLVRVALPRIRDFKGIESKLDGRGNYTLGIQEQIIFPEINIDNITKILGMNITFVT
                     SAKTDEEGYALLREFGLPFKNGKKD"
     gene            complement(14805..15125)
                     /gene="rplX"
                     /locus_tag="ACZPB4_00990"
     CDS             complement(14805..15125)
                     /gene="rplX"
                     /locus_tag="ACZPB4_00990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009132598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HIR1096835.1"
                     /translation="MSKLHIKKGDIVFVNAGEDKGKTGRVLQVLVKDNRAIVEGINVV
                     SKHTKPNAKNPQGGIEKKEAPIHLSNLNVVDPKSGKATRIGRKLNEKGALVRYSKKSG
                     EEIK"
     gene            complement(15145..15510)
                     /gene="rplN"
                     /locus_tag="ACZPB4_00995"
     CDS             complement(15145..15510)
                     /gene="rplN"
                     /locus_tag="ACZPB4_00995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009318509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HIR1096836.1"
                     /translation="MIQQESRLVVADNSGAKEALCIRVLGGTRKRYATVGDVIVVAIK
                     SVIPASDVKKGAVSKAIIVRTKKEIRRPDGSYIRFDDNACVLLNAGGDIRGSRIFGPV
                     ARELRATNMKIVSLAPEVL"
     gene            complement(15512..15769)
                     /gene="rpsQ"
                     /locus_tag="ACZPB4_01000"
     CDS             complement(15512..15769)
                     /gene="rpsQ"
                     /locus_tag="ACZPB4_01000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005853980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HIR1096837.1"
                     /translation="METRNLRKERTGVVTSNKMDKSITVAIKWKEKHPIYGKFVNKTK
                     KYHAHDENNECNIGDTVKIMETRPLSKTKRWRLVQIIERAK"
     gene            complement(15779..15976)
                     /gene="rpmC"
                     /locus_tag="ACZPB4_01005"
     CDS             complement(15779..15976)
                     /gene="rpmC"
                     /locus_tag="ACZPB4_01005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013546678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HIR1096838.1"
                     /translation="MKIAEIRELSTKELLERVDAEVAAYDQKKINHSISPMDNPSQIK
                     QQRRLIARMKTELRQRELNNK"
     gene            complement(15982..16416)
                     /gene="rplP"
                     /locus_tag="ACZPB4_01010"
     CDS             complement(15982..16416)
                     /gene="rplP"
                     /locus_tag="ACZPB4_01010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016275273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HIR1096839.1"
                     /translation="MLQPKKTKFRRQQKGRMKGEAQRGNQLAFGSFGIKSLENKWITG
                     RQIEAARIAVTRYMQRQGQVWVRIFPDKPITKKPAEVRMGKGKGNPEGFVAPVTPGRL
                     IFEIEGVPFDIAKEALRLAAQKLPVTTKFVVRRDYDMQNQNA"
     gene            complement(16437..17171)
                     /gene="rpsC"
                     /locus_tag="ACZPB4_01015"
     CDS             complement(16437..17171)
                     /gene="rpsC"
                     /locus_tag="ACZPB4_01015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005656540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HIR1096840.1"
                     /translation="MGQKVNPISNRLGIIRGWDSNWYGGKNYGDTLLEDSKIRKYLNA
                     RLAKASVSRIVIERTLKLITITVCTSRPGIIIGKGGQEVDKLKEELKKITDKEVQINI
                     FEVKRPELDAVIVANNIARQLEGKIAYRRAVKMAIASTMRMGAEGIKIQISGRLNGAE
                     MARSEMYKEGRTPLHTLRADIDYALAEALTKVGLLGVKVWICRGEVYGKRDLAPSFTA
                     AKETGRRNDNAGGNRDKNFKRKRANR"
     gene            complement(17179..17589)
                     /gene="rplV"
                     /locus_tag="ACZPB4_01020"
     CDS             complement(17179..17589)
                     /gene="rplV"
                     /locus_tag="ACZPB4_01020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007662145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HIR1096841.1"
                     /translation="MGARKRISAEARKEAQKTMYFAKLNNVPTSPRKMRLVADMIRGM
                     EVFRALGVLKFSNKEAAARVEKLLRSAIANWEQKNERKAEAGELCVSSISVDCATTLK
                     RMRPAPQGRGYRIRKRSNHVTLFVDTLSKNDSQN"
     gene            complement(17642..17911)
                     /gene="rpsS"
                     /locus_tag="ACZPB4_01025"
     CDS             complement(17642..17911)
                     /gene="rpsS"
                     /locus_tag="ACZPB4_01025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007212071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HIR1096842.1"
                     /translation="MSRSLKKGPYINVKLEKKVLAMNESGKKAVVKTWARASMISPDF
                     VGHTIAVHNGNKFIPVFVTENMVGHKLGEFSPTRTFRGHAGNKKK"
     gene            complement(17932..18756)
                     /gene="rplB"
                     /locus_tag="ACZPB4_01030"
     CDS             complement(17932..18756)
                     /gene="rplB"
                     /locus_tag="ACZPB4_01030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005853970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HIR1096843.1"
                     /translation="MGIRKLKPTTPGQRHKVIGAFDKITASTPEKSLVVGKKSTGGRN
                     NTGKMTMRYIGGGHKQKYRIIDFKRNKDGIPATVKSIEYDPNRSSRIALLYYADGAKS
                     YIIAPNGLEVGQTVVSGSDAAPEVGNTLPMANIPVGTIIHNIELRPGQGAKMVRSAGA
                     FAQLTSKEGAYAIIKMPSGETRKILAACKATIGAVGNSDHALEKSGKAGRSRWLGRRP
                     RNRGVVMNPVDHPMGGGEGRSSGGHPRSRNGLYAKGLKTRAPKKHSSKYIIERRKK"
     gene            complement(18765..19058)
                     /gene="rplW"
                     /locus_tag="ACZPB4_01035"
     CDS             complement(18765..19058)
                     /gene="rplW"
                     /locus_tag="ACZPB4_01035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005844851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HIR1096844.1"
                     /translation="MGIIIKPIVTEKQTAITEKFPNRYGFRVSPDANKLEIKKAVEDM
                     YSVTVVDVNTINYSGKRKSRYTKSGIINGKQAAFKKAIVTLKEGETIDFFSNI"
     gene            complement(19070..19699)
                     /gene="rplD"
                     /locus_tag="ACZPB4_01040"
     CDS             complement(19070..19699)
                     /gene="rplD"
                     /locus_tag="ACZPB4_01040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005853966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HIR1096845.1"
                     /translation="MELSVFNIKGEDTGRKVTLNDAIFGIEPNDHAIYLDVKQYLANQ
                     RQGTHKSKERSEVSGSTRKLIRQKGGGGARRGDINSPVLVGGGRVFGPKPRDYEFKLN
                     KKVKSLARKSALSYKAKNNAIVVVEDFTMEAPKTKEFITIAKNLKVADKKLLMVLPEK
                     NNLVYLSARNLEKASVITASELNTYAVLNAVNLVLTESSVAVVEQNFKA"
     gene            complement(19699..20316)
                     /gene="rplC"
                     /locus_tag="ACZPB4_01045"
     CDS             complement(19699..20316)
                     /gene="rplC"
                     /locus_tag="ACZPB4_01045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016275270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HIR1096846.1"
                     /translation="MPGLLGKKIGMTSVFSAEGKNLPCTVIEVGPCVVTQIKTLEKDG
                     YEAVQLGFQEKKEKHTTQPEMGHFKKAGVAPQRHLAEFKNFETEYKLGDVITVDFLED
                     AGFVDVVGTSKGKGFQGVVKRHGFGGVGQTTHGQHNRARKPGSIGACSYPAKVFKGMR
                     MGGQMGNERVTVQNLQVIKVMPEHNLLLVKGSVPGAKGSILLIEK"
     gene            complement(20336..20641)
                     /gene="rpsJ"
                     /locus_tag="ACZPB4_01050"
     CDS             complement(20336..20641)
                     /gene="rpsJ"
                     /locus_tag="ACZPB4_01050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005782187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HIR1096847.1"
                     /translation="MSQKIRIKLKSYDYSLVDKSAEKIVKTVKATGAIVSGPIPLPTH
                     KRIFTVNRSTFVNKKSREQFELSSYKRLIDIYSSTAKTVDALMKLELPSGVEVEIKV"
     gene            complement(20664..22790)
                     /gene="fusA"
                     /locus_tag="ACZPB4_01055"
     CDS             complement(20664..22790)
                     /gene="fusA"
                     /locus_tag="ACZPB4_01055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005853959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HIR1096848.1"
                     /translation="MANNDKQLMFTRNIGIMAHIDAGKTTTSERILFYTGLTHKIGET
                     HDGTATMDWMAQEQERGITITSAATTTFWNYLGNRYKINLIDTPGHVDFTVEVERSLR
                     VLDGAVATFCAVGGVEPQSETVWRQADKYNVPRIGYVNKMDRSGANYYEVVRQLKDVL
                     GANPCPIQIPIGAEETFKGVVDLIKMKAIFWHDETMGAEYSVEEIPADLQAEAEEWRD
                     KMLEALAECDDAIMEKYFDDPSTITEEEIMVAIRKGTLAMQINPMTCGSSFKNKGVQT
                     LLDAVCAFLPSPEDTPAIEGTDPSDPDKIITRKPLFEEPLTALAFKIATDPYVGRLCF
                     FRVYAGSINAGSYVLNTRSGKKERISRLFQMHSNKQNPMEVIGCGDIGAGVGFKDIRT
                     GDTLCDENHPITLESMEFPEPVIGIAVEPKTQKDMDKLGMGLAKLAEEDPTFRVQTNE
                     ETGQTVISGMGELHLDIIIDRLRREFKVECNQGRPQVTYKEAITQPVELREVYKKQSG
                     GRGKFADIIVRMEPADESFEGTLQFIDEVKGGNIPKEFIPSVQKGFEKAMKNGVLAGY
                     PLDKLKVTLIDGSFHPVDSDQLSFEIAAIQAFKNASAKAGPVLMEPIMQMEVVTPEES
                     MGDVIGDLNKRRGQVEGMETSRTGARIVKAKVPLAETFGYVTALRTITSGRATSSMQF
                     SHYAQVSSSIAKQVLTEVQGRVDLIK"
     gene            complement(22813..23289)
                     /gene="rpsG"
                     /locus_tag="ACZPB4_01060"
     CDS             complement(22813..23289)
                     /gene="rpsG"
                     /locus_tag="ACZPB4_01060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019541343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HIR1096849.1"
                     /translation="MRKAKPKKRQILPDPVFGDVKVTRFVNHLMYDGKKNTAFEIFYS
                     ALETVKGKLPNEEKSALEIWKAALDNITPQVEVKSRRVGGATFQVPTEIRPDRKESIS
                     MKNLIIFARKRGGKTMADKLSAEIVDAFNNQGGAFKRKEDMHRMAEANRAFAHFRF"
     gene            complement(23443..23853)
                     /gene="rpsL"
                     /locus_tag="ACZPB4_01065"
     CDS             complement(23443..23853)
                     /gene="rpsL"
                     /locus_tag="ACZPB4_01065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005853956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HIR1096850.1"
                     /translation="MPTIQQLVRKGRETLVEKGKSPALDACPQRRGVCVRVYTTTPKK
                     PNSAMRKVARVRLTNGKEVNSYIPGEGHNLQEHSIVLVRGGRVKDLPGVRYHIVRGTL
                     DTAGVNGRTQRRSKYGAKRPKPGQAAAAAKGKKK"
     gene            complement(24073..24669)
                     /locus_tag="ACZPB4_01070"
     CDS             complement(24073..24669)
                     /locus_tag="ACZPB4_01070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HIR1096851.1"
                     /translation="MAAKYDFYKTPVSKDSTKRPRFHARIVSSGTIDTDDLAKRIHGR
                     CTVTPADVAAVLISLSEVTAEYLREGKRVHIDGLGYLQVTLQCPAVQSTHEIRAESIR
                     FKSVAFRPEVELKDSLKTMTLERAKYKSHSRQLEPDRIDQLLASYFAEHEYMTRVAFQ
                     RLCGLTSSTASRRLHQFVEAGKLRDIGTRHQSLYVPVR"
     gene            24984..25874
                     /locus_tag="ACZPB4_01075"
     CDS             24984..25874
                     /locus_tag="ACZPB4_01075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VapE domain-containing protein"
                     /protein_id="HIR1096852.1"
                     /translation="MKTVLDFLGQLWLRFLKPDGSITVPHPNEGKAKRSSDSNSILQK
                     SLETFLQERIEFHFNLLSEETEYRYKQLETDRFYPVTQRDLNSICMEARRTGIDCRDR
                     DVNRFVYSKEVKEYHPFRQYMEWLPEWDGKDRVSDLARRVSSEPLWVEGFHRWMLALA
                     SQWMGSDRMHANSLAPILVSERQGCQKSTFCKSLMPSSLVRYYTDSVDLSGSTQMEQK
                     LGLFGLINLDEFNRLSDRKMALLKNWMQMAGMNVRKAHAKHFPPTPPSLIYWHYEPEE
                     PIKRPHWKPPFPMRGGAKQD"
     gene            25822..25935
                     /locus_tag="ACZPB4_01080"
                     /pseudo
     CDS             25822..25935
                     /locus_tag="ACZPB4_01080"
                     /inference="COORDINATES: protein motif:HMM:NF017116.6"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(26104..27951)
                     /gene="mutL"
                     /locus_tag="ACZPB4_01085"
     CDS             complement(26104..27951)
                     /gene="mutL"
                     /locus_tag="ACZPB4_01085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HIR1096853.1"
                     /translation="MSDIIHLLPDHIANQIAAGEVIQRPASVVKELVENAVDAGASNI
                     QVNIKDAGKTLIQVIDDGKGMSETDARMAFERHATSKISTAEDLFSLHTMGFRGEALA
                     SIAAVAHIELRTRARGTELGTCLSIAGSNLESIEPEACNEGSIFSVKNLFFNVPARRK
                     FLKSNETEFRNIINEFERIALVNPQVGMSLYHNDAEIFNLPESGLRQRIINIYGKSLN
                     QKLLSLDAQSSMVTISGFVGRPDSAKKRGALQFFFVNGRYMKHPYFHKAIMQAYEQLI
                     PAGDMPNYFVYFTLDPSSIDVNIHPTKTEIKFENEQPIWQILMAATREALAKSSAIPT
                     IDFDVEDAIDIPVYNPVKKSEPSTYKAPKVQVDSSYNPFDTTSYKKPEFDWSKLYQGF
                     ENDRVAVQRESETFEDAPIEELPAEASDPEKLFTEVSNPCYQYKGRYIVTSLKSGLAI
                     IDQHRAHVRILFDQYLSNIRQQQGVSQQVLFPEIVEFTAAEAAVLPSLLEDLCFVGFD
                     LSNLGNDNYAINGLPAGIENLDPVNLVKDIVDRAIETGCAVHEKICEAIALSLAKAAA
                     IRPGKSLSLEEMDHLIASLFSCSDSNLTPDGKTIISMLTDEELERRFKC"
     gene            complement(27951..28253)
                     /locus_tag="ACZPB4_01090"
     CDS             complement(27951..28253)
                     /locus_tag="ACZPB4_01090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1096854.1"
                     /translation="MALFSFYNMRKPRQFDHKPIYWDPHKEALEERISKVKREMGVEE
                     PLEEYKPHIKGTFIEGTSHLKKSVGRGEDSRARRYKNVKLAVALAVLAAFFWYLFW"
     gene            complement(28283..29884)
                     /locus_tag="ACZPB4_01095"
     CDS             complement(28283..29884)
                     /locus_tag="ACZPB4_01095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OstA-like protein"
                     /protein_id="HIR1096855.1"
                     /translation="MRLINRLFLALLSCALSVGVFAQTQDSTVVAAKDSVAPKKTKVF
                     LEHANTLSFDKERNAEAQVLNGDVCFRHDSSYMYCDSAYFFEQTNSLEAFSNVRMEQG
                     DTLFVYGNYLFYDGNTQIAYLRENVRMENGQVTLFTDSLNYERIPDIGYYFDGGLIVD
                     SLNQLSSFYGQYSPSTKLAIFNDSVRLENEQFTLYSDTLHYNTDSKIATILGPSIIVS
                     DSGTIYSSRGWYDTVNNTSLLLDRSQVVSGDRILTGDSIAYNRELGFGEAFGNMSLQD
                     TAQHVMLEGQYGFYNEKSEYAFATDSARFLEFSQGDTLFLHGDTLKMTTVDSLYREVK
                     AYYGVRFYRTDMQGVCDSMQFNTRDSILYMYTDPIVWNEQYQIYGDTILIFMNDSSID
                     FAHVKQFAFAIQQIDSTAFNQLKGNDLKAYFEGQVVNQIDVSGNAESIFFPLEKDGSM
                     VGMNETKSGFLTIWLKDNKLDKLKIWPTPTGTMTPIPDLKPDQKYLKDFYWFDYIRPK
                     DKDDIYQVVKRKAQDAPKRSNKFVH"
     gene            complement(29881..31245)
                     /locus_tag="ACZPB4_01100"
     CDS             complement(29881..31245)
                     /locus_tag="ACZPB4_01100"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HIR1096856.1"
                     /translation="MMKKILSVFFLACCSCIVMAQDNVIDEIVWVVGDDAILRSDIET
                     QRLYNQNEGVRLDGDPYCVIPEQMAIQKLYLNQAKIDSITVNENQVIQSVDQWMNMAV
                     NQIGSREKLEEYFGKKFSQIKDERKEMVREQQVVQQMQHQLIGEIKLTPSEVRKYFSQ
                     LSQDSLPNIPTTVEVQIVTLEPKIPFEETDAIKARLRDFTEQVNSGKMEFSTLARLYS
                     EDPGSASRGGELGFMSKTQLLPEFANVAFNLKDPKRVSQIVQTEYGYHIIQLIEKRGD
                     RINCRHILLKPKVSDKELADATTRLDSLYNDLQANKFTFEEAATFVSYDKDTRNNKGL
                     MVNQDYESSNMGTPKFEMQELPQEIGKVVYGMKVGEISKPFTMLTNKQKEVVAIVKLK
                     ARTEGHKANLADDFQALKAIVEAKKREELLNDWITKKQKSTYVRISDGWRNCDFKYPG
                     WIKE"
     gene            complement(31271..32125)
                     /locus_tag="ACZPB4_01105"
     CDS             complement(31271..32125)
                     /locus_tag="ACZPB4_01105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HIR1096857.1"
                     /translation="MRIVFMFLTFVVLLGACKGSQPADTTDVLVSVKGRTLNRSEVNK
                     LIPRGISSADSLLLAEGFTKKWVKDVLVYDVALRNLGDEKEEVDKLVEEYRRSLVRYR
                     YQERLVEEKLKTDIRESDKLNYYEENQKKFILDKGLIKGLFLKIPVDAPGLTDVKKWY
                     KSTDVASLEKIEKYSVQNATIYEYFYDKWVDFDEVMDNIPIHVSNPNAFLKANKYVEV
                     ADSSYCYLLNIKEYLPSGSVEPYDYASSHVTEMLVNQRKVEFLKKFEDELYNDAIRSG
                     DVEFHSEP"
     gene            complement(32139..33725)
                     /locus_tag="ACZPB4_01110"
     CDS             complement(32139..33725)
                     /locus_tag="ACZPB4_01110"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HIR1096858.1"
                     /translation="MVKEFLMKKLLISLGVFACVTVNAQTASDSVVMTVAGKQVPLSE
                     FIFIAEKNGEVDLSNTKSVKNYVELFKNFKLKVAEAESLGIDQTSSFKSELDGYRAQL
                     IDSYMSDKEGEKAAARAVYDRGDHSVELTHILFRLPEKTVSKDTVAVYQEAMRVYERL
                     QKGEDMETVGKALAEKDKEHVACEYVRCLLPMQSLKVFEDAAYSLPIGVVSEPVRTKL
                     GFHLIKVHSRKPNPGRIHVAHILIAFPKDSAIQDSSAFLAKAQAIYKQVQEGADFGEL
                     AKEYSGDAASAKKEGVLPWFGVGEMVQPFEQAAFALSKPGDLSEVVETRFGYHIIKLI
                     DKKGRPSFEEEEKALSRRMGQGERNFELYKAFDDRMKKEYGYVFYPEAYAELQALCND
                     CFPTDEAFYEKAKDMNKTLMQLDGKDFPQAEFAYYIQRCPFSTKTYAGDFMQEIYDLF
                     IRDIVTTAERKNLETKHPEIPHLMQEYRDGILLFEVSNREIWSKPSAQQKVLEAKWIA
                     DLNKKYPVTVNWKLLKKLKK"
     gene            complement(33834..35309)
                     /gene="guaB"
                     /locus_tag="ACZPB4_01115"
     CDS             complement(33834..35309)
                     /gene="guaB"
                     /locus_tag="ACZPB4_01115"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005811276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HIR1096859.1"
                     /translation="MSFIADRVVMDGLTFDDVLLIPAYSEVLPRNVDLTTKFSRNITL
                     NIPMVSAAMDTVTEAKLAIAIAREGGIGVIHKNMTIAEQAKQVQTVKRAENGMIYDPV
                     TITKGKRVADALAMMAEYKIGGIPVVDEGGYLVGIVTNRDLRFEKDMNRSIDEVMTKE
                     NLVVTGQSTDMEAAAQILQEHKIEKLPVVDSHNKLIGLITYKDITKAKDKPKACKDSK
                     GRLRVAAGVGVTFNTFERVAALVDAGVDALVIDTAHGHSKGVVDVLKQIKAQYPHIDC
                     VVGNIATGEAAKYLVEAGADAVKVGIGPGSICTTRVIAGVGVPQLSAIYDVAKALEGT
                     GVPLIADGGLRYSGDIVKAIAAGGSSVMMGSLLAGVEESPGDTIIFNGRKFKSYRGMG
                     SLEAMQKGSKDRYFQDVEDDVKKLVPEGIAARVPFKGSLYEVIYQMVGGLRAGMGYCG
                     AHNIEELHKARFTRITNAGVQESHPHDVAITQEAPNYSRGE"
     gene            complement(35524..37704)
                     /gene="recQ"
                     /locus_tag="ACZPB4_01120"
     CDS             complement(35524..37704)
                     /gene="recQ"
                     /locus_tag="ACZPB4_01120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008764112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HIR1096860.1"
                     /translation="MAKKDHLTEELNRHFGFGTFKGNQKAIIENVLAGKDTFVLMPTG
                     GGKSLCYQLPSILMEGTAIVISPLIALMKNQVDAMRNFSEEDGVAHFINSSLNKSAID
                     QVKSDILSGRTKLLYVAPESLTKEENVDFLRQVKISFYAVDEAHCISEWGHDFRPEYR
                     RIRPIINEIGKRPLIALTATATPKVQHDIQKNLGMIDATVFKSSFNRSNLYYEVRPKG
                     TNIDREIIKYIKANEGKSGIVYCLSRKKVEEFADILKANGIKALPYHAGMDSQVRSAN
                     QDAFLMEQADVIVATIAFGMGIDKPDVRYVIHYDIPKSLEGYYQETGRAGRDGGEGQC
                     IAFYAYKDLQKLEKFMQGKPVAEQEIGKQLLLETAAYAETSVCRRKVLLHYFGEEYLE
                     DNCGNCDNCLNPKKQVEAKELLSAVLEVISTLKEKFKADYIVNILVGNETSEIQNYKH
                     NELEVFGSGQDEDDKTWNAVIRQALIAGYLAKDIENYGLLKITEKGKEFMKKPVSFKI
                     TEDNEFEEEEEEVPVRGGASCAVDPVLYSMMKDLRKKLSKRLEVPPFVIFQDPSLEAM
                     ATTYPITLDELQNIPGVGAGKAKRYGKEFIELIKKHVEENEIERPEDLRVRTVANKSK
                     LKVSIIQRIDRKVALDEIALTNGLEFTELLDEIEAIVYSGTRINIDYFLNDVMDEDHI
                     EDIYEYFKDSETDGLEDAIEELGGDYTEEEIRLVRIKFLSEMAN"
     gene            complement(37737..38969)
                     /gene="clpX"
                     /locus_tag="ACZPB4_01125"
     CDS             complement(37737..38969)
                     /gene="clpX"
                     /locus_tag="ACZPB4_01125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HIR1096861.1"
                     /translation="MAKTTGDTCTFCGRSSRDVNLLINGISGCICDDCARQAYEIVKE
                     QTGGKKTSFGLKQKDLPKPEDIKTFLDQYVIGQDDAKRYLSVSVYNHYKRLLQKVTAD
                     DVEIEKSNIIMVGATGTGKTLLARTIAKLLHVPFAIVDATVLTEAGYVGEDIESILTR
                     LLQAADYDVEAAQRGIVFIDEIDKIARKSDNPSITRDVSGEGVQQGLLKLLEGSIVNV
                     PPQGGRKHPEQKMIAVDTKNILFVCGGAFDGIEKKIAQRLNTRVVGYSASLDTATVDR
                     NNLLKYITPTDLKSFGLIPEIIGRLPILTYLNPLDRDTLRNILTEPKNSIIKQYVKLF
                     DMDGIKLTFDEKVYEFIVDKALEFKLGARGLRSIVEAVMMDAMYSMPSQKVKELHVTL
                     EYAKEKFEKSDVNRLQVA"
     gene            complement(38991..39653)
                     /gene="clpP"
                     /locus_tag="ACZPB4_01130"
     CDS             complement(38991..39653)
                     /gene="clpP"
                     /locus_tag="ACZPB4_01130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005853931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HIR1096862.1"
                     /translation="MEDFRKYATKHLGMSGTALDSYMNISSSYISPTIIEERQLNVAQ
                     MDVFSRLMMDRIIFLGTQVDDYTANVIQAQLLYLDSSDPGKDISIYINSPGGSVYAGY
                     GIYDTMQFISSDVSTICTGMAASMASVLLVAGTKGKRFGLKHSRVMIHQPLGGVQGQA
                     SDIEITAREILKVKKELYTIISDHSGRPYEEIERDGDRDFWMTAEEAKKYGMIDDVLT
                     RK"
     gene            complement(39843..41195)
                     /gene="tig"
                     /locus_tag="ACZPB4_01135"
     CDS             complement(39843..41195)
                     /gene="tig"
                     /locus_tag="ACZPB4_01135"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005853929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HIR1096863.1"
                     /translation="MNVSLKNNDAVSGIVKLEIVKADYADQVDKSLRSLRQKANVPGF
                     RKGMVPMGMVKKMYGKHVLVEEINKLVSENLFKYIRENDLHILGEPMPNETEQKPLDF
                     DKEEDFEFCFDVALAPEINIELSKNDKLPFYQVAIDEEMLNNQVNAYRSNFGSYDKVD
                     EVEEKDMVKGTVAELENGAPKEGGIVVEDAVLMPMYIKDEEEKAKFIGAKVNAVVVFN
                     PNKAYEGAEAEIASFLKIDKEKVAETTGDFSFEIKEITRHKDAEMNQELFDKVFGENV
                     VTSEEEFKNKIKEALAEQFAPQSDFKFLTDTRDMLVERAGELNFADDLLKRWLLAANE
                     KNTKEKIDEDFPQILQDLKYQLIKENLVKKNGLKVEDADIENFAKRVAKAQFAQYGML
                     SVPEDVLDNYAKDMLKNKQTLQNIIDRAVEEKLAAWLKEQVELDVKEVTADEFNKLFE
                     "
     gene            41339..42226
                     /locus_tag="ACZPB4_01140"
     CDS             41339..42226
                     /locus_tag="ACZPB4_01140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HIR1096864.1"
                     /translation="MRIKGIYATRPAIIQLLILLLFLLAGAILSSIISTGLLLATHGL
                     QADITQDANLMRLIQFISAICTFLLPSIAMAWICSDNPCHYLSVKKITDGRIWILTLV
                     CVFLFSPVINLLGLLNKQMELPAFMAPIEEWMRAQETLAEQLTTILLSSDSVWVILAN
                     LIVIAVTAGITEEFLFRGALQRVIGKWTSNPHTIIWVAAILFSAFHLQFYGFLPRMIL
                     GAYFGYLLYWSKSIWIPVFAHFVNNAFAVIGMSDSRLKDNEFITGDIPAEHLLDFCLI
                     AALSFLLFILVNRRLKRLL"
     gene            complement(42221..42973)
                     /gene="lptB"
                     /locus_tag="ACZPB4_01145"
     CDS             complement(42221..42973)
                     /gene="lptB"
                     /locus_tag="ACZPB4_01145"
                     /EC_number="7.5.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0015221 - lipopolysaccharide transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015920 - lipopolysaccharide transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter ATP-binding protein"
                     /protein_id="HIR1096865.1"
                     /translation="MSDEQRMVLRTEDLVKKYRTRTVVNHVSINVKQGEIVGLLGPNG
                     AGKTTTFYMTVGLVTPNEGKIFLNDMEITKFPVYKRARNGIGYLAQEASIFRKMTVED
                     NIRSVLEMTGRSIEYQKEKLESLISEFGLNKVRKNLGDQLSGGERRRAEIARCLAIDP
                     KFIMLDEPFAGVDPIAVQDIQTIVARLKHKNIGILITDHNVYETLSICDRAYLLFEGK
                     VLFQGTAEQLAENEIVREKYLGKDFVLRKKDL"
     gene            complement(43058..44173)
                     /locus_tag="ACZPB4_01150"
     CDS             complement(43058..44173)
                     /locus_tag="ACZPB4_01150"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HIR1096866.1"
                     /translation="MKRILLGVIGLLCLCVACLRKDLSFKPGEVWPDDKGVHINAHGG
                     GILRVGDTYYWFGEHKTEGSAGNLAQVGVHCYSSKDLYNWKDEGIALSVVPDDTTSHI
                     VKGCVLERPKVIYNKKNDQYVMWFHLEPRGAGYSGALSGVAVSKNVAGPYSFVNAFRP
                     NAGFWPVNVQELHKQPCTLSADLRFSGGELPAHPDSLNLLGRDQISGQMARDMNLFVD
                     DDGIAYHIYSSEENSTLHISQLTDDYTSYSGKYARFFPGRFMEAPALFKQKGKYYLIM
                     SGCTGWAPNAGRSAVASSIWGPWKELENPFRGENSEVSFYSQSTYVLPVPGHADRFIY
                     MGDRWTPENAIDGRYIWLPIRFEGEQPVIEWRSEWSY"
     gene            44349..45095
                     /locus_tag="ACZPB4_01155"
     CDS             44349..45095
                     /locus_tag="ACZPB4_01155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008149992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MlaE family ABC transporter permease"
                     /protein_id="HIR1096867.1"
                     /translation="MNKALHRMGEYTLLMMKSITLPDRWSMFFKQLIKEIYKLGVDSL
                     WIVIIISVFIGTVIAIQISLNISSPLIPKFTIGYTTREIILLEFSSSIMALILAGKVG
                     SNIASEIGTMRVTEQIDAMEIMGVNSANFLILPKMLGLMIFIPVLVIFSMFTGIMGGI
                     FASYSTSTGMTPSSFEYGLQFYFNEFYIWYSIIKSVVYAFIISSIAAYFGYNVKGGAL
                     EVGKASTNAVVMSSIMILLADVILTHLMLT"
     gene            45098..45868
                     /locus_tag="ACZPB4_01160"
     CDS             45098..45868
                     /locus_tag="ACZPB4_01160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005853918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1096868.1"
                     /translation="MIEVKNITKSFDGRVVLKDISTTFEDGKTNLIIGRSGSGKTVMI
                     KNIIGLMKPDTGQILYDGRDLITMNKHELNMLRREMGMLFQGSALFDSMTVMENVMFP
                     LDMFSKDSTKERRKRAEFCLERVNLSEAGHLYPSEISGGMMKRAAIARAISLNPKYLF
                     CDEPNSGLDPKTSLLIDDLIHDITVEYNMTTVINTHDMNSVMNIGDNIIFIKEGVKEW
                     QGTKEQVITSNNQALNDFIFASDLFRKVKEVEMLQEEG"
     gene            complement(45983..47269)
                     /gene="metK"
                     /locus_tag="ACZPB4_01165"
     CDS             complement(45983..47269)
                     /gene="metK"
                     /locus_tag="ACZPB4_01165"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005853916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HIR1096869.1"
                     /translation="MSYLFTSESVSEGHPDKVADQISDALLDEFLAYDKNSKVACETL
                     VTTGQVVLAGEVKSSAYVDVQEVARGVIEKIGYTKSEYQFEAKSCGVFSSIHEQSGDI
                     NRGVERADPYEQGAGDQGMMFGYATNETENYMPLALDLSHSLLWELAKIRKEEPDLMP
                     YLRPDAKSQVTIEYDDNGKPLRIDTIVVSTQHDEFIGPKGISQKEADEAMQKRIALDV
                     KKILIPRVKAQYPAHVQALFNDNIIYHVNPTGKFVIGGPHGDTGLTGRKIIVDTYGGK
                     GAHGGGAFSGKDPSKVDRSAAYAARHIAKNMVAAGVADEMLVQVSYAIGVAKPMNIFV
                     NTFGRAKVNMTDGEIAAKIWDIFDMRPKAIEERLKLRNPIYFETASYGHMGRKPQTVT
                     KTFSSRYLQKPVTCDVELFTWEKLDYADKIKDVFGL"
     gene            complement(47519..47713)
                     /locus_tag="ACZPB4_01170"
     CDS             complement(47519..47713)
                     /locus_tag="ACZPB4_01170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1096870.1"
                     /translation="MNKEINKAMTQGIVFKKAKGEAEDSNGKKIKFSDFLKGTHGSDS
                     AKWKAGFKYKKALRNSKKKK"
     gene            complement(47744..48202)
                     /gene="folK"
                     /locus_tag="ACZPB4_01175"
     CDS             complement(47744..48202)
                     /gene="folK"
                     /locus_tag="ACZPB4_01175"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003848 -
                     2-amino-4-hydroxy-6-hydroxymethyldihydropteridine
                     diphosphokinase activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HIR1096871.1"
                     /translation="MATAYLGLGTNVGNKRGNLVTAAALLAERVGDVLALSDMYETEP
                     WGFESDNTFLNAVIVMTTELSPMELLDATRLIEIEMGRIEKSDGAYHDRIIDIDLLMV
                     DEQILHTERLTLPHPLMHKRSFVMEPLAEVAPLVKHPVFGKTMRELLSEL"
     gene            complement(48213..49262)
                     /gene="queA"
                     /locus_tag="ACZPB4_01180"
     CDS             complement(48213..49262)
                     /gene="queA"
                     /locus_tag="ACZPB4_01180"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008150013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HIR1096872.1"
                     /translation="MKLSKFKFNLPSELIALHPAKNRDESRLMVVHRDTGEIEHREFK
                     DILDYYGKGDVFIFNNTKVFPARLYGNKEKTGARIEVFLLRELNEDLRLWDVLVDPAR
                     KIRIGNKLYFGEDDSMVAEVIDNTTSRGRTLRFLYDGNHDEFKKALYALGETPLPKYI
                     EREVEPEDEDRYQNIFAAEEGAVVAPAAGLHFSRELMKRLEIKDCQFAFLTLHSGLGN
                     FREIDVEDLTKHKMDSEQMVVNADVVDIVNKGKDEGHKVCAVGTSVMRAIETAVSTDG
                     HLKEFEGWTNKFIFPPYDFSVATSMVTNFHMPLSTLLMMTASFGGYELIMDAYDIALK
                     EKYRFGAYGDAMLIL"
     gene            complement(49275..49982)
                     /gene="truB"
                     /locus_tag="ACZPB4_01185"
     CDS             complement(49275..49982)
                     /gene="truB"
                     /locus_tag="ACZPB4_01185"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HIR1096873.1"
                     /translation="MDFIAGEILYFNKPLTWTSFDLVNKFRYKLSRKLKVKKIKVGHA
                     GTLDPLATGVMIVCTGRATKRIDEFQYQTKEYIATLKLGETTPSFDLEKEIDAVYPTE
                     HITRELVEEVLKTFVGTIQQIPPVFSACKVEGKRAYELARKGEEVELKSKTLVIDELE
                     LLECDLPVIKIRVVCSKGTYIRALARDIGKALDSGAHLIGLERTRIGEVTLDMCMSPE
                     EIDDFLEQNVVKIEEEK"
     gene            complement(49986..50786)
                     /locus_tag="ACZPB4_01190"
     CDS             complement(49986..50786)
                     /locus_tag="ACZPB4_01190"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005812416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HIR1096874.1"
                     /translation="MSWFEALILGIVQGLTEYLPVSSSGHLAIGSALFGIEGEENLAF
                     TIVVHVATVFSTLVVLWKEIDWIFRGLFKFQMNAETKYVINILISMIPIGIVGVFFKD
                     TVEQIFGSGLLVVGCMLLLTAALLAFSYYAKPRQKESISMKDAFIIGLAQACAVMPGL
                     SRSGSTIATGLLLGNNKAKLAQFSFLMVIPPILGEALLDVMKMVKGEDVAGDIPALSL
                     AVGFMAAFVSGCVACKWMINIVKKGKLIYFAIYCAIAGLVTIACTLLK"
     gene            complement(50783..51022)
                     /locus_tag="ACZPB4_01195"
     CDS             complement(50783..51022)
                     /locus_tag="ACZPB4_01195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005853907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3098 domain-containing protein"
                     /protein_id="HIR1096875.1"
                     /translation="MAKRDFAFGKENFILIAVAVACIVLGFILMSGGGSGDNTFNPDI
                     FSARRIVVAPVVTVIGFVMMIFGILKNSKDKEVTE"
     gene            complement(51050..51928)
                     /locus_tag="ACZPB4_01200"
     CDS             complement(51050..51928)
                     /locus_tag="ACZPB4_01200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008150016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsX"
                     /protein_id="HIR1096876.1"
                     /translation="MAENKKVSSVSFFNSRLTSVISISLVLFLLGLILLIGMLGNKLS
                     VYVKENLSFSIVLKDNQKETEIKKMQKSLDALPFIKSTEYISKEQAAKELEEELGENP
                     EIFLGFNPLQASIEVKLHSEYANPDSLQVIEKKIRNYTSVSELLYRKDMMEIVHNNMK
                     RLGLILLTLAAVLMIISFVLISNTIRLLIYSKRFLIHTMKLVGATSGFIRRPFVKYNI
                     VSGIFASILAILMLTGALYYLQNELKGFIQILDMQTLLLVYVAVFALGIVLSVIATIF
                     AVNKYLRMGVDKLYYI"
     gene            complement(52178..57523)
                     /locus_tag="ACZPB4_01205"
     CDS             complement(52178..57523)
                     /locus_tag="ACZPB4_01205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HIR1096877.1"
                     /translation="MKKSILAIFLAVIAMAQVHAQDSDLRSAPDLPTFKVTLNYSSAN
                     TDQGTITSTVATGSKVAYNSKPVFTITAKPGYVLSDITMNTATIGTLPSGTFQNDNTT
                     TYSYTSTALTGSTEIKAVFKAKEQVTVTISPEYATLDEIRAKVNLPKVTFDPVITGYK
                     VQYREDGSAALTDELPEKAGLYYVVVTKSETDTQVAINKEILFKVQPPHTLSYSFEEA
                     QGSVTASMDGSIIASGDEIVYNKPAVLKIASKPGYVLSRLTVDNNEVTLPKGTFNSST
                     NETSYADYTTSALTASTVIDVRFAAKKTVSVTANPLSATKDEVLAGKNLPVITFTPNT
                     IAGQKVQYKNASGALSDKLPAADGVYTIVATSPETAEYAALKDENMKFTVSKANVLNY
                     NVETAGQGTVTAKMGSTDMASGSEIINGQPAVFTIIANPGFLLNKIVVNGTAVSALPK
                     GALNKDNTISYTYTTASLTASTTLSVGFAAKKTISVSVTGSSATKDEIVAGKNLPVIK
                     FTPEIAGQAVRYRAADGSETSTLPQIVGAYKIVLFSPETMEYAALEDSSKTFTIRNAN
                     TLAYAVDGGQGTVTAKMDNKDIMSGGEIAYGKPVIFSIVSNANYRLGAIKQASSDVDI
                     SKIKGTYANGNTSYTYTTPNLMSGDSYTFAFVSKDTVRFVANNLVQTVGSIKPVTVTS
                     AVEDIKIEYQLSGTAWVTTLPSTLAVGSYKARLSRAEDLTYRSLSDTVTLVVESKKEV
                     ESLVLPTPGRIEEGQALSACTLIDGTSSGSFIWKTPNEIASPDKKKYDLIFEPNDPVL
                     YAAKDTFITLNVIPVYSMNVTAGNFGTVILEGRTANDKYARGSVLKATAVADKNYRFA
                     GWSDGNTSATRELQANTNLDIVARFDSIVYGVTFTNPMNGSLKVFANGVEVKNGAEFL
                     QGTLLTITATPDPGYMVQSVKVNGALVNNGSYTLIQAADISADLLQKEPDKHLVKVGE
                     LKNGSVNLIEVDTKAPVTPGEAISEGVKVKVIGNADYGYELASVKVEGANYNEADGSF
                     MVGTGDVTVSASFQLVKYQITSALNIPNAGKVVLKDKAGKEVASGSKVPYMTQLTASV
                     ETETGYRFMNMMVNSSEIKDRDVFTVSGPMVVTANYVEKKDLASLIDKTTQTVVYNKQ
                     YRNFEVKITGYSGLDFKVAYSRSGVEMTENPKSAGTYKVRITRGEDDLFKAVDVTAEL
                     IIKKAGMALLEVPTIGGDNYEKVDAKLTQDFEDVEWNPSKQKSALRANVTGSPTMDQV
                     NILRFTPLDKSNYESVDYSMPVGEVKTFSLSASNTEVTNGGLVISDYSKIPENTVLKL
                     RAVAPSENLCFDSWGENVSSTDRENPEITVTLVADATYAPNFVDKPKITANTSDLEFV
                     YNGSVKLVELKDILSGSYPTDVNIKYSNTDGSVATPLNAGTYLVTVTRTGDENWRSFE
                     ATKKLVIKKAKVVEVVAPTASTITEGQSLSESLLSGGVAKGADGTTISGKFEWADASA
                     ILKPGDSQKKEVIFTSYDPNYEDATTNAEVTVKSSDALVVTFAQPENGSLKVYMLKGE
                     GEKTEITSGTAVAKATKLTIETEANPDYELAVIQIGEEKYTTSPVEIEVDKSLAIIAE
                     FKPVSTPPGTDVAVTGVSLNITSKALAVGESFALQEKVTPNNATMKTVSWSSSDETVA
                     TVDADGVVTALKIGTCKITVATDDGNKTASCVVTVSGTVGIEQIIDDHQIYCERGAIT
                     VHPARPISIRIIAVTGVSLYGDSIIGPTRIPVSTGIYLIEINENGKHITVKVNVR"
     gene            complement(57544..61191)
                     /locus_tag="ACZPB4_01210"
     CDS             complement(57544..61191)
                     /locus_tag="ACZPB4_01210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005853896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1096878.1"
                     /translation="MKRRLLFLFAVFMVGASVGWGQMIPTYYKVAVGTGGDGSSAGSP
                     IYKANLEAALSDAALSSLDSVIILLPEGEYSANAAPYSITKSSLAIIGEGDTSTVTIK
                     SPVDIELTNGGNVSFQKVHLTAKTSTGRGVVDIKSSKTTVSFSESKITIEGRGTGDSG
                     SGACFGIVSQLTVDENTVNFINSRMYMSEGFERGLAFRDGGGHTLNFIGSKMEGPSAK
                     GLYPYVIGICSWVGGTDNTNPVTYNIRNSVVDVNYYAIFAINQAGYTNAVNITIDNSS
                     VTAWAALFLRGDLVNEAYPHNVAISNTHLYGRSYQNGPSDGFGTVVLDNCQNLTMTMD
                     SKSSIVSENKAPIDSPITYMCVADVRKNTSGTWTFTSTDGSKALIQSKNDKYAPTLFF
                     DDAGTNLEVLGVENVEFKTENEKPCIVSIHKNGTLNNAASNLDVLLTNMILEEEDKVI
                     FPEGEYTLPMTLPLDKSITIQGTGRDKTIIKGAILINGSANNTATDVKIKGLSIDYTP
                     TKVTSGKCTPIIEVTGNADLLIDNCIMNNNTQGYGDRKNPNPAEVLQNAILLGATAKG
                     TVHVENTTINLAANAQAGVLIDGELTDVSLVNTKIDGQVNGSNQFGVYIHHKKTPVTV
                     DSTTILLNNHYCIYANNAGDQKLTIKNKSNIVGYGALYLYETSDMNVHVSGGSILTGK
                     TKNKGVSDSFAAIAISTNNSTVGASNNEIVIEDSYIGNKFDEQETMAMTPIKINGSFT
                     PTPCDNKIILKGKTIVSTTDNIKNPTIVGYGMNPDEYNNVIMVEGTDVQFQDQKGKPC
                     VIINKPDGSFRNAAVSIVTAIDFGELYGSTYYHEGIAYAGDIILIPDTTMAETLNSLN
                     AAKPNFFPDVDTWEPYTIPDGVIFNCKDGRLVIEENTAKAYAIANPFKRVYWLNQGAQ
                     SFSIKECVVAIDIKSDTTWATSFQDRQVNILNGATLTVSVPMALDTVMMEEDAQVVFT
                     ATEGKLTARSLRFAPLLSATGWKAFGMPFTSAVIKNSTEEEISAPSAQNVDNGIWFAR
                     LKDNKTPEFVVDESAFGMAGLWAANGDTYTISSEGAFEFKTLEEAAAPTETGTFLMCS
                     NPNTFTITLKQSAYILTADGTSFEQEANPEIKPFQSFVLTDAKTLSTLRSLRIGDGVV
                     TGNQTIEPVDGYYVTTDRGAIVIHTPEPMDVVIIGMNGKVAYRSEVTDGQRIMVPSGI
                     YAVNGQLVRVK"
     gene            62737..65847
                     /locus_tag="ACZPB4_01215"
     CDS             62737..65847
                     /locus_tag="ACZPB4_01215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SusC/RagA family TonB-linked outer membrane
                     protein"
                     /protein_id="HIR1096879.1"
                     /translation="MKSKMRTWNVAMGSLSLLFLCVSPALAIATNPSQENPYTERNDD
                     SVTQQRTRKVTGVVLDANGESIIGANVVVKGTNNGTITDLDGKFSIELSDGETLQVSF
                     IGYNSKDVMVGAGENHIKVQLREDTQKLDEVVVVGYGTQIKRAVTGSVQSIKSEEMAD
                     MPVAQISQKMQGKFAGVQINQVSGKPGQGMTMRIRGQASLSGGTTPLYVVDGMPIVGD
                     ISTINPDEIESISVLKDASATSLYGSRAANGVVLIQTKTAQSGKKLSVDVYGGIQYVP
                     EKGRPDMMDASEYARFRKEIAEENGLAVDPAYQHPEALGKGTDWYDVLFRPAAIQNYS
                     LSYSNGDGKFKSSTVASYFNQDGVLTNSNYQRFSARANTEYVFSKIVKVGVNLAPSFS
                     INNSPQSDGNWTEDKGSILQGAMLTTPLAPYKNEDGSIPLVASGPGLFDNPNWYNVVR
                     LNKNKTQNTHLIANAFLEVEPVKDLKVKTSINADLTQNKWNSFKPSTSGEIYKAPYQI
                     PEAKESNNLFYTWLWENTATYSKQIKDHSFDLLFGISAQKYHSEYTMVTGTNFPDDKI
                     STFNAAPTITADGNINEWSLLSYIGRINYNYKGKYLLSAAMRRDGSSRFGKNNRWGNF
                     PSVSAGWILSDEEFMKPLEKTISFLKARISYGIVGNDQIGNYTHLATITTTNSNFNNA
                     LASGRSISGMGNPNLGWERNKQVDVGLDVGFFNNRLSIMYDYYSKRTDALLFSLEVPI
                     SSGFYNIQSNAGKLKFWGHELSVSSKNLTGKLQWTTDLNVSYNDNKCLQLGVDDAPII
                     GNNITQVGERIGQFYGLVWEGVYKNKEEFDKYPKHAQADVGTIRFKDVNGDGKVTQGD
                     DRDIIGNPVPLWIVGMTNSFTYKNFDLSIVVSGGFGFELANMVDQFAGNLDGVFNVYK
                     AVDNRWKSPENPGNGRYGTTKMGTTAPERDWFSSRFLYNGNYLTIKNITLGYQVPLRN
                     RDIIKGLRAYVSFQNVYTFTSYIGANPEVNISNTGTTANSLQQGFDYTTYPVPRTITL
                     GLNVNF"
     gene            65869..67455
                     /locus_tag="ACZPB4_01220"
     CDS             65869..67455
                     /locus_tag="ACZPB4_01220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RagB/SusD family nutrient uptake outer membrane
                     protein"
                     /protein_id="HIR1096880.1"
                     /translation="MKTIFNIAISIALGCSCASCSDFLNLTPYSEITAENFYQNEEDF
                     RQAVNGAYEPLRNMYNTEEWNLGEAKSDNTTYIIHIAKSSLDGEDPDQFLETSTNGNV
                     GTKYNNCYVIIGRCNRIISEIDQADFDAEAKSNLKGQALFLRAFCYFNLVQYFGGVPL
                     HTTPSTVYEEAFKPRASVDEVYEQIMKDAQEASDLLPVKSRQEVGRVSKGSAQTLLGN
                     VYMVLKRWAEAEQTLKEVVSSGEYELLADYGSIYSISNKNHKESIFEIQYMQDASLGQ
                     QSDFIYRFLPYMTNPSAITGTTPNPCPSNVDHGGFNTPTIDLINAYEKGDKRLDASIG
                     MVEGKLTDSYALDATGVKSIVDYEPAPGITAYPFIKKYFHEHIKPYYTDDNWPVYRYA
                     EVLLFLAEAINEQNRPDEAIHYLNDTFGQASIRGRAGLAPVKSQNVDALREAIYQERR
                     IELAFENKRWTDLLRTGRAVEVMTRHGQKIKANPESYYWPDGVQPVANAYLFNPDKCL
                     LPIPLREIDLNSELKQNPGY"
     gene            67480..69123
                     /locus_tag="ACZPB4_01225"
     CDS             67480..69123
                     /locus_tag="ACZPB4_01225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005853887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-rhamnosidase-related protein"
                     /protein_id="HIR1096881.1"
                     /translation="MKRAHMKILLSLLCCVGVFTLSAQSRYFKESASWLQKSEACKPV
                     LTYTEHKPVKRVTSIKDASAYQGWRMRDEGSTDLLFNESLKKHPSVIVDFGEHLTGYL
                     DFSLKLLSQQVSDAPVRIKFTFAEVPSELNTPFDPYPGGLSRAWLQDEVMTLMTVPIE
                     ASIPRRVSFRYLKIELLGASSFDFAFDKLTFRAQTSAKTAPLPLASTTDPLIRKINEV
                     GLLTLKECMQTVYEDGPKRDRRLWIGDLYLEALANAWSYKNHDLTKRCLYLLAALAND
                     EGLLHATVLETPTPHPQNGTHCLDYSLLYNVALLEYLKETGDKEVALDLWPVVVRQIE
                     MALRQYSDDWIYDMQKKPIYWLVFDWKDNYDRQASMQGLTAFSLEKSYELAKMLGKEK
                     EAGDWPRIAGQIKKAARKTFYDQKNGVIVSGPNRQVSYLSQVWMILSETLTAKEGAKA
                     MATVLSMPDACYPGCPYAYHYVMEALLKCGMRQEARSLLTSYWGGMVNKGADTFWEVY
                     DPNNDELSPYGFFPINSYCHAWSCTPVYFINKYPEIFQR"
     gene            complement(69184..70557)
                     /gene="miaB"
                     /locus_tag="ACZPB4_01230"
     CDS             complement(69184..70557)
                     /gene="miaB"
                     /locus_tag="ACZPB4_01230"
                     /EC_number="2.8.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016782 - transferase activity,
                     transferring sulphur-containing groups [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (N6-isopentenyl
                     adenosine(37)-C2)-methylthiotransferase MiaB"
                     /protein_id="HIR1096882.1"
                     /translation="MVNQENGVDLKSATQSDERKLFIETYGCQMNVADSEVVASIMKM
                     DGYSMTENIEEADAIFVNTCSVRDNAEQKIYGRLQYFQSLKRKKKSLIVGVLGCMAER
                     VKEDLIHVHHADLVVGPDSYLDLPNLVGAVEHGEKAINVELSTQETYKDVIPLKLPGV
                     HISGFVSIMRGCNNFCTYCIVPYTRGRERSRDIESILNEIRDMHEKGFKEVTLLGQNV
                     NSYSFEKEGETITFPILLDRVAKEVPDMRIRFTTSHPKDMSDDTLRVIAANDNICKFI
                     HLPAQSGSSRILKVMNRKYTREWYLDRIAAIRRIVPDCAISTDLFCGFHSETEEDYQE
                     TLSLMREVGYDSAFLFKYSERPGTYAASHLEDNVPEEEKVRRLQGMIDLQNKLSEESN
                     LRDIGKTFEVLIEGFSKRSREQLFGRTSQNKVVIFDKKNYHVGQFIKVKIHKASSATL
                     FGEPVEE"
     gene            70818..71273
                     /locus_tag="ACZPB4_01235"
     CDS             70818..71273
                     /locus_tag="ACZPB4_01235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1096883.1"
                     /translation="MDNVGDWLYIVFLIIAAVSGLFSSKDKKKKSRPDILGQPDREIV
                     PNDQPTEGKGFWEILEDMQKETQKPKPAPRQKQVKPKVEKPQVVTSSPASSPFLSAEK
                     NIPNHIATQPSVRMSAIEEEPGLMPEDTFRDIEELKKAIICAEILNRKY"
     gene            71375..72871
                     /locus_tag="ACZPB4_01240"
     CDS             71375..72871
                     /locus_tag="ACZPB4_01240"
                     /EC_number="2.8.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005634657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008775 - acetate CoA-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0006083 - acetate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006084 - acetyl-CoA metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase family protein"
                     /protein_id="HIR1096884.1"
                     /translation="MALKFITAEEAASYVHHNDNVGFSGFTPAGCPKVVPGAIARKAA
                     EEHAKGNPFQIGMFTGASTGDKLDGELARANAIKFRTPYQSNKDLRAALNAHQAQYFD
                     LHLSELAQSLRYGFLGKIDVAIVEAADVTEDGEIVPTSGVGILPTICRMADRIIVELN
                     CRHPKEIRGMHDIYEPADPPLRREIPIYTPSDRIGNDCVKVDPAKIVGVVRTDEPNEG
                     GKFSPLDDVTMAIGKNVADFLVSEIKAGRLPKEFVPLQSGVGNVANAVLGCMGANESI
                     PAFNVYTEVIQDAVIELMKQGRVKFASGCSLSVSNEVIREIYANLDFFKDKILLRPQE
                     ISNNPEVARRLGLIAINTALEADIFGNINSTHVSGTRMMNGIGGSGDFTRSAMLSIFT
                     TPSTAKEGKISAFVPMVSHLDHSEHSVKIIITEYGVADLRGKSPIQRARCIIDNCVHP
                     DYKPLLEEYLAMGIKGHTPQNLKCCFAFHEELAASGDMHNVDWSKYNK"
     gene            73051..74238
                     /gene="pstC"
                     /locus_tag="ACZPB4_01245"
     CDS             73051..74238
                     /gene="pstC"
                     /locus_tag="ACZPB4_01245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HIR1096885.1"
                     /translation="MRKFIEKLVEGGFLISGSVSSFTILLIIVFLFKEAAGLFNSPEV
                     EEGYILAVNQENPVEHLSPEQIMDVFDANITNWEDLNGENQDILVFRFSDLTNYYTEE
                     ELGEEFQYVPEKINELIHKEPGIIAFFPEQYKSENFTGKIISGATIKPSEFFGGTKWY
                     PTSAPAPIFGLIPLLLGTLLVSIGAIALSLPFGVAVAIYMAEIANTKTRNLLKPIIEL
                     LAGIPSVVYGFFGLVVIVPLIQKTLDLPVGETAFAGSVVLAIMALPTIITVAEDAMRT
                     TPRAMKEASLALGATQWQTIYKVIIPYSISGITSAVVLGIGRAIGETMAVLMVTGNAA
                     VIPTSFFEPVRTIPATIAAELGEAPAGGAHYQALFMLGAVLFLITLGLSIAVEYISSK
                     RKI"
     gene            74247..75134
                     /gene="pstA"
                     /locus_tag="ACZPB4_01250"
     CDS             74247..75134
                     /gene="pstA"
                     /locus_tag="ACZPB4_01250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HIR1096886.1"
                     /translation="MAPIQHLGNIDKRKRTSQQVAFGFFSFLSYLVVVILFVILGFII
                     LKGASVISWDFLTQAPQEGMTSGGIFPAIVGTLYLVIGSSLISFPIGIMSGIYMNEYA
                     TNGKLIRFIRIMTNNLSGVPSVVFGLFGMSLFVSTLGWGDSIIAGSFTLALMSLPLII
                     RTTEEALKSIDDSFRHGSLALGATKLQTIRRVVLPMAFPNIITGLILSIGRVSGETAP
                     ILFTVAAYFLPQLPKSIFDQCMALPYHLYVISTSGTDIEASRGMAYGTALVLIVIVLL
                     VNLLANALRSYFAKKVKMN"
     gene            75150..75902
                     /gene="pstB"
                     /locus_tag="ACZPB4_01255"
     CDS             75150..75902
                     /gene="pstB"
                     /locus_tag="ACZPB4_01255"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005634638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HIR1096887.1"
                     /translation="MIKIDAKNVDFYYGDFHALKNISMEIEPNTSTAFIGPSGCGKST
                     FLRLFNRMNDLIPDTRMEGQILIDGRDIYTKSERVDRLRKNVGMVFQKPNPFPKTIYE
                     NVAYGLRVNGVNDENYIEETVVKTLKQVVLWDEVKDKLKESAFALSGGQQQRLCIARA
                     LAISPSILLMDEPTSALDPISTSKIEDLIHELKNDYTIVIVTHNMQQAARVSDKTGYF
                     YLGELIEYDNTRKIFTNPEKESTQNYITGRFG"
     gene            75934..76608
                     /gene="phoU"
                     /locus_tag="ACZPB4_01260"
     CDS             75934..76608
                     /gene="phoU"
                     /locus_tag="ACZPB4_01260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005853873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HIR1096888.1"
                     /translation="MKVIEQEIHSLKNSISEMWALVHQQLYNAGEAMLTGDKELAYKV
                     ISRERRVNAFELKIDSDCEDIIALYAPVAIDLRFVLAMYKINTNLERLGDFAESIARF
                     AGNLPEGEPIDPQLVKETRVEEMLSELLSMISLTKEAFEKESSEIASRIFLKDNLIDE
                     INHNSTAIIAKYIEEHKGSALAGLYMAGVIRKMERFGDHCTNIAEELIFYLDAKVMKH
                     MGKTEQ"
     gene            76649..77863
                     /locus_tag="ACZPB4_01265"
     CDS             76649..77863
                     /locus_tag="ACZPB4_01265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005853871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OprO/OprP family phosphate-selective porin"
                     /protein_id="HIR1096889.1"
                     /translation="MKRLTVAWLSAFLLSGSALTSYAQTNSPIPERDSSSVSLFEYAT
                     KIPKRNKVFNLDLEMHAGFNADFFSGKLDEAAFRFRDVKIDVTGEVNDRLFYWYRQTL
                     NGGYEGQALENLNESIEYAYIGYKLNERFTLTAGKQDVFYGGFEYDENPLLIYEYSDM
                     NEYSLCYLTGIGLGYQPNESQEIRLQVTNSRMGSMEDEYGRLPEGFKKPRVPLFYTLN
                     WNGNFLDELIHLRYSVSAAEQAQGKYMYSVFTGQSIEAGPVYAYFDVMYSRGKLDPLG
                     LLTELTQPEVSGEEEPEPPVRMQNIDYLSLVGEIQYRFHPKWQLFAKGMYESASIYKA
                     YDAYEKGKYRTAWGYQGGLEFYPMADDNLHIFLTAIGKKYNLSERAKALDASLDDTAR
                     LSIGFIYRLPLY"
     gene            complement(77947..80376)
                     /locus_tag="ACZPB4_01270"
     CDS             complement(77947..80376)
                     /locus_tag="ACZPB4_01270"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005853869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HIR1096890.1"
                     /translation="MKGLYLILLSFLFGCNLPDMQTGKEVSYYFDQPAQIWEETLPLG
                     NGRIGMMPDGGIERENVVLNEISLWSGSKQDTDNPYAYYSLANIRRLLFEGRNDEAQD
                     LMYKTFVCKGTGSNLGDGANAPYGSYQLFGNLVLKYTYPNESDSIAEYRRRLNLSEAI
                     ASVSFKRGNVNYQREMFTSFSGDLGVIHLVADTDRALNFSLGMNRPEHATISLDGKDL
                     LMRGQLPDGVDTLEMKGMRFASRVRIVLPKGGDLATTDSCLSVRSASEAIILVSLGTD
                     YFDKDGAGQSLEKYLSQAESKDFSTLRREHTLAYRSLFDRVSLDLGRGERDHLPINER
                     LAAFAQDKNDPGLAALYFQFGRYLLISSTRQGLLPPNLQGLWCNTIHTPWNGDYHLNI
                     NLQMNHWPAEVTNLSELHLPLIEWTKLQVPSGERTAKAFYNARGWVTHILGNVWEFTA
                     PGEHPSWGATNTSAAWLCEHLYTHYQYTLDKAYLRDVYPTMKGAALFFVDMLVQDPRT
                     KYLVTAPTTSPENAYKMPNGSVVSICAGSTMDNQIVRELFTNTIEAAGILGVDSAFAA
                     ELAAKRDRLMPTTIGKDGRIMEWLEPYEEVEPTHRHVSHLYGLYPGNEISIEHTPELA
                     EAARKSLEVRGDQSTGWSMAWKINFWARLQDGDHAYKLLGDLLRPCVDEHTKEVKGGG
                     SYPNLFCAHPPFQIDGNFGGTAGIAEMLIQSQTGLIEFLPALPSAWKNGSFSGLKVRN
                     GGEVSAKWTEGLLTEARLKAIVPGIFRIKLPANSANLSLKKNQKPVSLPVIDGMLTVD
                     LQQGDELILIM"
     gene            complement(80459..82306)
                     /locus_tag="ACZPB4_01275"
     CDS             complement(80459..82306)
                     /locus_tag="ACZPB4_01275"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005634625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1096891.1"
                     /translation="MRDFIRILKRFVPPYKKYMVLNIVFNVLSAILNLFSFALIIPIL
                     QILFKMDEGNYTFMDWNFNAGSWESWKALPELIKNNFFWYVSDLIEVHGGSFALIMLG
                     IFLIVATFLKVATMYLAFYTMIPIRTGVVRDIRNQINKKITQLPLSFFSEERKGDIIA
                     RVSGDVNEIETSIMSSLDMLFKNPILIVIYLVGMIAISWQLTVFVLILLPLAGYVMGQ
                     VGKKLKRKSLEGQQQWGFLMSQIEETLGGLRIIKAFNAEKKIQDRFERSNDTFRRLTN
                     RIYRRQQMAHPMSEFLGTVTIAIVLWYGGTLILSANSPIDAPTFIYYLVIFYSIINPA
                     KDLSKSVYAIQKGLASMERVDKILKAETDIHDPEHPKKIALKEKISYKDVWFKYQEAW
                     VLKGINLDIRKGTTVALVGQSGSGKSTLVDLLPRFYDVNKGNIRIDDTDIREATLFDL
                     RGLMGNVNQEAILFNDTFFNNIAFGVEGATMEQVEEAARIANAHDFIIASEKGYDTNI
                     GDRGGKLSGGQRQRISIARAILKNPPILILDEATSALDTESERLVQEALENLMKNRTT
                     VVIAHRLSTIRNADEICVMHEGEIVERGKHEELLALDGYYKRLCDMQSF"
     gene            82463..83305
                     /locus_tag="ACZPB4_01280"
     CDS             82463..83305
                     /locus_tag="ACZPB4_01280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005853865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM-associated putative lipoprotein"
                     /protein_id="HIR1096892.1"
                     /translation="MENINLQLLRKINCLLTGLLAIIGFSCGENGEIPCEYGSPHANF
                     QIKGKVTDMKGEPIPDLQVRINPSGESHPQGWLHTDTLQTDTNGDFIFSKTDFPFMEY
                     RLIIEDIDWDKNKAIYASDTITVTFDSNDFSGGEGWSLGSASKEIQIQLKEYIDTHTE
                     PYTLYTFYGRVTDQDGWPVPGVTIYTSPAYTPNIDEDITSFPAVTDETGRYQFTYDQA
                     PATEHTLYARLSPSFSDPQYPWKTDSIVVNFGEIELIDGEGMLIGRGSKEVNFQLVHS
                     SPQK"
BASE COUNT        23192 a        20560 c        16488 g        23169 t
ORIGIN      
        1 tctttgccca tccacaatat tgtctctcaa tgtgcgaagg gcatttttga ataagtcaaa
       61 atctgttgtt tcaatcgcaa cctgtctata tgctttgttc agagcttgat tcggtttgag
      121 tagtcccata atgtttggta aataagttaa taaaatacaa aggtagccta aaaacttgat
      181 aataaagaat gaacgtattg gtttaacgaa agtttgttct actgccagcc gttatcaaca
      241 gacaatagca gacagtagat ttgacatgat tctacttatt atattgtaat agtcagtcaa
      301 agtaatcttt tcacatccgg atctatcata ggttggataa gttgttaacc tgaaggtaac
      361 cggtctgatg gtataggaac aaaaagaagt ctgtaatcat ggcatttact cgggttagag
      421 aagccacatc tttttattgc cggacttccg gcattgtttc atccatgtgc gaaaaggagt
      481 tttttctttc atcgcaacgt ttctttcaca tacccaaagg ggggcgtgaa tccagacccg
      541 cttcagtttt ctttttcctc cccatatgac acaaaacgac tatccatgac tattcctgcc
      601 ggtcgtgctt gcttctcatg ttttccttaa tattcttcct tccgaggtta ttccgatgtg
      661 acggtgatgg agagccctcg tatccacgta ggccagaccg gtcagcgagg gaagatgaac
      721 accctgcgca ccagttccat catcaggtcg ggcatcggga tttacgtcat ccgtttctgt
      781 tcactgcggc tgatatgctt taatttaggt gcttctttct tctcgtatgc catatctttt
      841 atcgggttgg gccacaatac tttcctgtct acagcgatat atatgagccg gttgggccag
      901 cacaagcaat gattcatgtg cccgttcctg cgtctcaact ccttcttgag aaagatcttg
      961 aacgattcgg cgaactcccc ggtgatgtct gaaaaggtga tgcccttcgt ttcgcgggat
     1021 tcgatgaact gcctgagatt gagctgtgtg gttttcgact ggcggtaggt ggagttaatc
     1081 tccttggagc ggatcctaag acgttctcgt tccacctctc cggcttacag gaggtattcc
     1141 gacacggaat tggcatctga tacagtgatc ttgagcagtt cgaccgtaac cactccctgg
     1201 ttcctctgca ggttcccata tgcctcttcc tgtcggttac gaagggtggt aaggcgggtg
     1261 ttttctttga ccgttgaaaa aatccgtttc cgtgaaaaaa gaaaatggat tcaagataaa
     1321 aactatttaa accaagaaac tttatcgggg aaatttttcc tgtataaatt tgctaacatc
     1381 aagaatatca actacttttg tagctgaaga gttatttgag gttatgcaga aaaacgcaag
     1441 caagcgatgg attttcgtca cccaatcgtt acctgtctgt tttctatgct ccgcttatct
     1501 tttgaaactc aaaaagttaa agagaactac gctattttaa caagcaaata cccgttatcg
     1561 tttaagacga tcttctccgt tagctgataa atcgagaggg tttgttggag ggtcgtgtct
     1621 cctacaaagc gaccgtcgaa agcgagagac aggactagcg agtccagtac gaccgtctcg
     1681 tccggatcag tcccatagct aggtctttca taagcgataa agctatgcga cgagacgact
     1741 ccccataatg aatgtttgta ccggcctacc aaagcgacgt tcttaccaga tgtctccaac
     1801 gagtcgatca ataccgaggt cactacgacc gtgctggtat ctatacgaat gttacggaaa
     1861 gcggagtcca ccagatcgct gccatacgta ccgttctcgt cataacagga aaacagtccc
     1921 agacagagca tcaagcaccc caaagcaaag aatgttctaa ccatacttct tatttaataa
     1981 gcaaataatc ttttatcaat ccgatggcaa agaacgtatt tagcgcaaaa cccggcaaga
     2041 taaacccatg aacccaccgg tttcctctgt aaacggcccg atactgaaga tgaaaccgat
     2101 ttcaaaacca ttcgaggccc taacctataa atccggctta ttcaccgata aaaaccgtat
     2161 gtttaccgat ttaatttgtg ggtctcgtaa aaccctcgtt cttttgcttc cgtaaaaaca
     2221 aaatacgtag ttagaatgat acacaaaagg attcttgtat tcttgatcgc ttttcttcct
     2281 gtcatcatca gcgcttgcag tgatgacgat gacgatgatt tgatcggtaa gtggtaccgt
     2341 gtctctgaca tggacggatt ggcgcgaaat tacgcctcct ctttcacgat cggtaacaaa
     2401 ggatatctga tttgcggaaa cgacggaaaa aatcgtttat cggattgttg ggaatatgat
     2461 atggaacgag atacttggac gcaaaaggcg gactttcccg gaaccgcccg caattcggcc
     2521 gtagctatgg cggtagatga aaagggatat ctgggaaccg gatacgacgg taccaattac
     2581 ttgaacgact tctgggaatt taacccgacc accaatacgt gggcacagaa agcggatttc
     2641 cccggctcgg gccgatatgg agccgtggcc ttcggggtaa acggtaaagc gtatatcgga
     2701 tgcggatacg acgggaatta cctaaaagac ttttatgcct ttaatccggt ggcaaatagc
     2761 tggacgcaaa cgatcagtat cggcgggaca aagcgtcagg gcgctaccag cttcgtgata
     2821 aatggaatcg cttatgtatg ttgcggacaa aataacggcg aatatgtaga cgatttctgg
     2881 aaattcgatc ccagcacgga atcatggacc caacttaggg atatatcgga ttcctcggac
     2941 gaggattatg acgatgatta tacgatcaca cgtacgaacg gggttgcttt cgtgattgat
     3001 ggagccgctt atctgacttg cggtgagagc ggaagcctac gtagcgacac ttggaaatat
     3061 tatccggcca ccgatctatg ggaaaacgta gctaaattca agggaactgc ccgtacggcg
     3121 acagcatctt tctcctctgg cgagaaagga ttcgtagtat ccggcaaaag tggtaccact
     3181 caatttgatg atatttggga atttcacccg aatgaatatg acgatgatga atactaagaa
     3241 aggacgggct tggttcgtac cgggcctagt ggtactgccg gtattactgt tttatttatc
     3301 ttttttccgg ggtgaagaaa tggggtcttc tcccgggcgg caactggagt tgcaaacatt
     3361 tcaatcgggg gatggctggg ggtaccagat taggatgaac ggaaaggtgt tgatttacca
     3421 acccaccatt ccctctattg atacggtaat tgcgttcccg gataaggaaa gcgcagaaaa
     3481 cataggcaca ctcgtattaa ataaattggc cgggaacagg aacttctcgg tctctagaga
     3541 agagatacaa cattcactct cttatttagg gcaatagatt tataatcatt aaatgtttgg
     3601 agcaggctgg ctattgatta gtaggtttgc ttcgtttttt ccactaaaaa gaaaaaggga
     3661 gtccaccttg ataggtgaac tcccccattt ctcaagcaaa taatgaaaat tacttcttat
     3721 aagtcttata accataaaca gccaaggaac ccaattcctc ctcgatacga agcaactggt
     3781 tgtatttcgc catacgatcg gaacggctta aggagccggt cttgatttgt ccgctgttgg
     3841 tagctacggc gatatcggcg atcgtagcat cctctgtctc accggaacgg tgggaagtca
     3901 cggatgtata gccattacgg tgggccatct cgatagcgtc taatgtctcg ctcaatgtac
     3961 cgatctggtt taccttgatc aagatggagt tcgcgcaacc cttctcgata cctttcttca
     4021 agaactctac gtttgtaacg aataggtcat cacctaccaa ctggcatttt ccgcctagcg
     4081 tggaggttag catttgccaa ccggcccagt cattctcgtc cataccatcc tcgatagaat
     4141 caatcgggta tttgttcacc aactcactca gataagcgac ttgttgctgg gcgttacgct
     4201 tagcgccttt ctcaccctcg aatttcgtat aatcatacac accatcgtga taaaactcgg
     4261 aagcagcgca atccatggct atcgtcacat ccttgcccgg ctcatatcca gcggctttga
     4321 tagcggccat aatagaattc aaggcatctt ccgtaccatc caatgccgga gcgaaaccgc
     4381 cctcatcacc tacagccgtg ctcaagccac gatcgtgcaa tactttcttc aacgcatgga
     4441 aaacctctgc gcccatacga agcccctcac ggaaactctt cgcacctacc ggacgaatca
     4501 tgaattcctg aaaagcgatc ggagcgtcgg agtgagaacc tccattgata atgttcatca
     4561 taggaaccgg caacacgtag gtatttgttc caccgatata acgatataaa ggcagatcca
     4621 gataattagc cgctgccttc gctacggcaa gcgatacacc taacatagcg ttagctccta
     4681 gatttgattt tgtctttgta ccatccaaat ccagcaactt atggtctatc tctctttgat
     4741 tcaaggcgct cattcctaaa atggcgggag cgattacctt atttacatta tccacggcac
     4801 ggagaacgcc tttgccaccg tagcgattct tatcgccatc gcgtaactcg atagcctcgt
     4861 tctcaccggt agaggcgcca gaaggtacag ccgcacgacc gaatgcgccg gaagccaaat
     4921 gtacgtctac ttctactgtc gggttaccac gtgaatcaag tatctctcta cctactactt
     4981 ttacaatttc catattacta tatttgtttt attagttgtt caatgatgtc ttacttttct
     5041 ttttcacaaa tataacaata gccaagcaag gaatgtttgc ggaagcctat cgagtttttc
     5101 aatcttttaa tagatgattt ttactatttg cctaaacctt tcaaaaaaag cttttgttgt
     5161 ttatgaaaga atatactcat actaagatga aaaaggtact taccactatt gactcttcta
     5221 gatttattcc tgctgtttgg caaaggggag ttcatttatg cggataccgc atctgtccct
     5281 ccggaatata aagcttgcct gtgctcttct tgtgaagatc atattgatga taatcaccat
     5341 accggatact cttttgatca agaggatgga gaagtcatcg caaaagggct ttccactgaa
     5401 ccggataatt tcttaccgca acgtctgaat ttgtacaacg ctttcgagac gaaagattat
     5461 gataatggca tacaacaaac ctctggattt ttcaacacgc ctaatggaaa gttcatttgg
     5521 caagattatt tataccaaga ccgcttatta aatgcgactc agcaatatga accatcttta
     5581 gagaatctct caaaagcagt gaaactagcc gaatactatc gttatctggg ctatttctat
     5641 tacctcaaaa agatctggac aattcaaaaa tatactggaa taaggtctta gagatcgatc
     5701 cttctaataa ggtagcgcag gaggctcttc aaagcataca ataaaaacaa ttataaactt
     5761 catatttctt tacactgcta tatttgcact atacctcaac aaaaaaagcg atccgtgtgt
     5821 acgaatcgct tttcttatat gattataaaa aacttgctta ttcagctgct ttttcctcgc
     5881 tagctgcttc agctgtagga gcttctgcaa ccgatgctgt tgctttttta cgagaacgtc
     5941 ttgttttagg agctttctta gcggctgtat ccttcaacat attttcgtta tagtctacta
     6001 actcaataaa gcacatagct gcgttgtcac ctaaacggtt accagtcttg ataattctgg
     6061 tataaccacc cggacgatca ccgatcttct gagcaatttc cttgaacaac tctgttacag
     6121 caaatttgtc ttgcaaattg ctaaatacca cacgtctaga gtgagttgta tcctccttag
     6181 acttcgtgat aagtggttct acatacttac gtagcgcttt tgcctttgct gtcgtagtaa
     6241 agattctctt atgcttgatc aaagaacaag ccatattcga aagcattgcg tcacggtgag
     6301 tatttgtacg acctaaatga ttgaatttct tattatgtct catcgtttac ttactcttta
     6361 tctaatttat attttgtgat atccataccg aatgaaaggt tcaagctctc aagcagttca
     6421 tcaagttcag tgagcgactt tttaccgaag ttacggaatt tcaacaaatc attcttattg
     6481 aacttaacca actcacctag tgtttcaaca tctgcggcct ttaagcaatt caatgcacga
     6541 acggaaaggt ccatatcagc cagcttgctc ttaagcaact gacgcatatg aagtacttct
     6601 tcatcgaact cttcattgcc ttcagtatcc gctgtctcga tcgcaatctt ttcatctgag
     6661 aacaacatga aatgatgaat cagaatcttc gctgcttcct tcaacgcttc cttcggatga
     6721 atagaaccat ctgtggctat ttcaagaacc aacttctcgt agtccgtctt ctgttcaaca
     6781 cggaagttct cgattgaata ttttacgtta cgtatcggag tgaagataga gtcgatagcg
     6841 atcacatgta tatctgcgtt cgggtctctg ttctcatctg cgggtacata accgcgacct
     6901 ttattaatag tcaattcaat ctggaaactt gcggtcggat ccaagcggca aataaccaaa
     6961 tcaggattca atatctcgaa tccagtcagt tgcttaccaa tatcaccggc tttgaacact
     7021 tccgaacccg aaacagtaat actcactttt tcattctcga tgtcgtctac gatatgcttg
     7081 aaacgaactt gcttcagatt caagataatg tttgtcacat cctcgataac acccgggatt
     7141 gtaccaaatt catggtcaac cccgtcgatc ttaatggatg taatagcaaa accttcaagt
     7201 gacgacagga gaatacgacg taaagcatta cctattgtaa taccatagcc gggttccaac
     7261 ggacgaaatt caaactttcc gaagaaattg tccgcttcca acattaatac tttatcgggt
     7321 ttttgaaatg ctaatatcgc catggaaatc aattattatt tagaatacaa ttctacgatc
     7381 aactgctctt taatgttttc aggaatgtca gctctttccg gcagatgcag taattttccg
     7441 ctcattgagg actgatccca ctcaatccaa ggatatttgc tgtgattgaa acctgacaat
     7501 gcgtcggcaa taacctccat ggatttagat ttttctctaa caccaataac ctgaccgggt
     7561 tttacagagt aagaaggaat gtttacaaca cttccgtcta ctgtaatgtg acgatgagaa
     7621 accaactgac gagctgcggc tcttgtcggg gctataccca aacgataaac cacattgtca
     7681 agacggcctt ctaacaattg aagaagcacc tcaccggtaa tacctttaga gcgtgaagct
     7741 ttttcgaata agtttctaaa ttgcttctcc aatacgccat aagtgtattt tgctttttgc
     7801 ttctcacgaa gctggatacc gtattcagaa gtctttcttt ttctggagtt accatgttgt
     7861 ccaggaggat agttcttctt agaaagaact ttatccgcac cgaatattgc ctcaccaaac
     7921 ttacgggcaa ttcttgttct tggtccagta tatcttgcca tttttttatt tttttaaatg
     7981 ttctgtttga atctggaacc gtgcagccgc gattacagag aggataaggt caatatgcaa
     8041 tctattcaca attccggatt caatgtttaa gaaactataa ttaattatac tcttctcttt
     8101 ttcggaggac gacacccgtt atgaggaagc ggtgtaacat caacgatttc tgttacctcg
     8161 atacctgcgc catggatcgt tctgatagcg gactcacgac cgttacccgg acccttaacg
     8221 aatactttca cctttcttaa accaagatca taagctactt tagcgcaatc ctgtgctgcc
     8281 atctgagctg cataaggagt attcttctta gagcttctga atcccatctt accagcggaa
     8341 gaccagctga ttacttgtcc ttcgctattc gctaaagaca caataatgtt gttaaaagaa
     8401 gaatgaatat gagcttgacc gtaagcgtca acttttacgt ttctcttctt tgctgcgact
     8461 gttttctttg ccatattaac tcttattatt tagtagcttt tttcttattt gcaacagttt
     8521 tcttcttacc cttacgagta cgagcgttgt tctttgtgct ttggcctctc aaaggcagac
     8581 caacacggtg acgaacacct ctgtagcaac caatatccat cagacgcttg atgttcaact
     8641 gaacttctga acgaaggtca ccttcaacct tgtactcagc gccaatgact tcacgaactt
     8701 ttgcggcttg atcgtctgtc caatccttaa ctttgatatc acgatcaacc ccagccttat
     8761 ctaatacgga ttttgcagcg ctacgaccaa taccatagat ataagtcaaa gcgatttctc
     8821 ctcttttatt ttgtggcaag tctacaccaa ctattcttat agccatatta cttacttaga
     8881 ttattttgca aaaataataa attatccttg acgttgttta tacttaggat ttttcttgtt
     8941 aattacgtat aagcgaccct ttcttcttac tatcttgcac tcaggtgtac gcttctttaa
     9001 agatgctctt actttcatat cgtgtttaat tttatttgta tctaaaagca attctacctt
     9061 tcgatagatc atacggagac atttctactc ttaccttatc ccccggaagg atcttaatgt
     9121 aatgcatacg catctttcct gagatatgag cggtaatttc atgtccgttc tccaattcta
     9181 cacgaaacat cgcatttgac aatgcttcta caattactcc atctttctct attgctgatt
     9241 gtttagccat ataaatccaa ttaaattgcg ttttctccta gaacttcctc taaaaactta
     9301 aatgaagata agatctgggg accatccgga cgtatagcga tacaatgctc gaaatgagca
     9361 gaaggctttc tgtcctttgt gcgaaccgtc catccgtctt tctcaaatgc aacgttcttg
     9421 cttcccatgt tgatcatcgg ctcgatgcag atacacattc cgttacgcaa taacggtccg
     9481 catccacgtc tgccataatt aggcacttcc ggttcctcat gcattttccg acctatacca
     9541 tgtcccacca gctctcttac gacagagtaa ccttgagact cgcaataagt ctgaatcgca
     9601 ttactgatat cacccaaacg gtgaccttca acagcacatt ggatacctaa ataaagtgaa
     9661 tccttcgtcg ctttcaacaa tttcttcact tccggcgcaa cctcacctac acagaaagtg
     9721 taagcggagt caccgacaaa accattcaat atcgtcccac aatccacaga gatcacgtca
     9781 ccctctttca agatcatctt agaagaagga ataccatgca ccacctgatc attcactgag
     9841 gcacatattg aattagggaa accaccatat cccaaaaaag ccggaacagc accattatct
     9901 ctaatgaact cttccgcaat cttatcaagt tgaagtgtgg agactccggg gacaatatgc
     9961 ttagctacct cgccaagtgt cttacctacc agttgattag cctcacgcat caactcaatc
    10021 tcttcatctg tctttaaata gatcattcta ttaataagcg gcaacagagc ctgtacggcc
    10081 tttaattctt cctgacttca acaaaccgtc ataatgacgc attagcaaat gactttcaac
    10141 ttgctgcaat gtatccaaca ccacaccaac caaaatcaac aaagatgtac caccaaagaa
    10201 ttgggagaac tccatactta caccggcaat tctagcgaaa gcgggcatga tagcaaccaa
    10261 cgcaaggaaa aaagcacccg gcaaagtaat acggtccata atggtatcca gatagtcttt
    10321 ggtattctta cccggtttca cacccggaat aaaaccattg tttctcttca aatcatctga
    10381 catctgggtc ggattgatcg taatagccgt atagaaatac gtaaacagga taatcaacac
    10441 cgcaaacacg aagttgtacc aaaatcccgt attatccatg aaagcagccc aaaaaccgct
    10501 ctgctctccc gtactagaga aacctacaat tgagatagga ataaacatga tcgcctgagc
    10561 gaagatgata ggcattacgt tagcggcatt caccttcaga gggatatact gacgcgcgcc
    10621 accatattgt ttattaccga taattctttt cgcatattgc acggggacct tacgagtacc
    10681 ttgtaccaat aagatcgcac cagcgataac aagcaaaagg aacaacatct caaataagaa
    10741 cataaccaga ccaccggttt tctcacttgt tctagaaacg aattcttgga acaaagagtg
    10801 cggcagacgg gctataatac caactaaaat gataaatgaa ataccatttc caacaccttt
    10861 atctgtaatt ctttcaccta gccataagat aaacatactt cccgcagcca agatgatcgt
    10921 agatgagatc gtgaaccaaa taccacccgg taaagcagcg ccggcagcct taagctgaac
    10981 gcttaaattc accaagtaag taggaccttg gaataacaag atcgctatcg tcaagtaacg
    11041 agtccactga ttgatttttc tacggccact ctcaccctct ctctgcaatt tttggaaaga
    11101 aggaactgcg atggctaaca actgcataac aattgaagcg gagatatatg gcatgattcc
    11161 caacgcaaaa atagatgcgt tagaaaaggc tccacctgag aacatatcca acagtgcaag
    11221 caatccgcct cttgtctgct cctgtaaagc ggttaacgct ttgggatcga tacccggaag
    11281 cactacatac gtaccaaaac ggtatatagc caccaataaa agagtggtga ggatccgatt
    11341 tctcagatcc tcaatcttcc agatattctt gattgtttca acagctctca tgacttagag
    11401 tttaacgact gttccacctg cggcttggat agctgcctct gcgctcttag agaaagcgtg
    11461 agcctcaacc tctaacttag cggtcaagct accgttacca agaattttaa ccacttgaga
    11521 agaagagatg aaaccagcct ccatcaattc attaatacca atcttagtca attgcttagc
    11581 ctctgccatt tgttgcaaag tatcgatatt aatagcttta tattctacac ggttaatatt
    11641 cttgaaaccg aatttaggca aacgtctttg aataggcatc tgaccacctt cgaaaccaat
    11701 cttgttcttg tagccagatc tagacttggc acctttatga cctcttgttg aagttccgcc
    11761 taatcctgaa cccggaccac gtccgattct ttttctggtc ttggtagatc cttcagccgg
    11821 ttttaaattt gataaattca tatcgtataa tttatttttt caaccaatta ttacttttct
    11881 acagaaacca aatgtttcac tttctcaacc atacctaaga tcgccggatt agcttcatgc
    11941 tctacaatct ggttcatctt tctcagccct agtgcgtcaa gcgttctctt ttggtctttc
    12001 gggcatttaa ttctactttt aacttgcttt actttaatag tcgccataaa cttatccccc
    12061 cctaattaac ctctaaatac tttttcaaca gcaacacctc tgttctgagc aacatcgaac
    12121 gggcttctca actcacctag cgcagcgata gtagctttca ccaagttatg agggttggaa
    12181 gaacctttag attttgccaa aacgtctgta atacctacgc tctccaatac ggcacgcata
    12241 gcaccaccag ccttaacacc ggtaccgtga gatgccggtc taatcagcac ttgagcacca
    12301 ccgaatttag ctaattgttc gtgagggatc gtacctttgt gtaccggaac cttgatcaag
    12361 ttcttcttag cagcttctac acctttagcg atagctgtcg ttacctcacc ggctttacct
    12421 aatccccagc caacgatacc atcctcgttt cctactacaa cgatagcagc aaaactgaat
    12481 gtacgtccac cttttgtaac cttagttaca cggttgattg caaccagtct gtccttcaac
    12541 tctaagtcgt tggtcgattt aactctatta tttgccatct tcattaaaat ttaaggccgc
    12601 cgttacgtgc agcatctgct aattctttaa ttctcccgtg atacaggtaa ccattacggt
    12661 cgaaaaccac tgtctgaacg ccagcttcct gagcgccttt agcgattaat tcaccaacct
    12721 tagcagcgat ctcctttttc ggagccttaa catctaattt caaagatgaa gcagcggcta
    12781 aagtcttgcc tgtagtatca tctatcacct gtgcgtagat ttgcttgttg cttctaaaca
    12841 cagtcaggcg cggacgctca gtagttcctg agattttgcc gcgtacgcct gcttttattt
    12901 ttaatcttct ttctagcttc gttgtcatga taatttcagt ttacgtagat tacttacctg
    12961 ctgacttacc agactttctg cgaatctctt cacccacgaa cttaataccc ttacctttat
    13021 acggttcagg cattctgaat gaacggatct tcgcacaaat ctgacctaat aattgtttgt
    13081 cagccgattc aaggataata agagggttct tatttctctc agacttcgtc tcaactttca
    13141 cttccttcgg caactgcaaa tagatattgt gagtataacc taaagaaaga tccaataact
    13201 gacctgtatt tgaaacacgg taaccaacac ctactaactc aagctccttc ttatatccct
    13261 ctgagcagcc aacaaccatg ttgttgatca aagaacgata caaaccgtgt aacgcacgat
    13321 gattcttatc atcagtaggt cttgttaaat ggataactcc gtcttccaaa gtaacgttaa
    13381 tatcaggatt cacttcctgt acaagttcac ctttagggcc tttaactgtt actacattat
    13441 ccttaattgt aactgtaaca ccagccggta catgaattgg taattttcct attcttgaca
    13501 ttcttcttcc ctcctaatta ataaacgtaa cataatacct cgccaccgat cttcagatcg
    13561 cgggcctctt tgtcagtcat cacaccttta gaagtagaaa gaacagcaat acctaaacca
    13621 ttcaatactc tcggcatttc tttgtaacca gtgtacttac gcaaaccggg cgtagaaact
    13681 ctctcaagtt tcttaatcgc attaactttg tttactaggt catacttcaa ggcgatcttg
    13741 atcgtacctt gaggaccatc ctctacaaac ttaaaattaa gaatgtagcc cttgtcgaaa
    13801 aggatcttag tgatctcttt ctttaaattt gacgccggca cctcaacaac tctgtgcttc
    13861 gctttgattg cgttacgcaa tcttgtcaaa taatctgcaa taggatctgt catataaata
    13921 attaattaaa ttgatccggc cacccggaca atatttaaac taaaaaaact cttaccaact
    13981 tgctttcttt acacccggga ttaaaccatt agatgccatt tcacgcaatt ggatacgaga
    14041 aataccgaac tggcgtacat accctttcgg acgtcctgta atcttgcaac ggttgtgcaa
    14101 acgtacagga gaagcatttt taggtaaagc ctgcaaagcc tcatagttac cttctgcctt
    14161 aagctgagct cttttagcgg catacttagc aacaagcttt gctcttttaa cctcacgggc
    14221 cttcattgat tccttagcca taactactta gtcttttttt ccgtttttaa aaggcaatcc
    14281 aaattctctc aaaagagcat aaccttcttc gtctgttttc gcagaggtca caaaggtaat
    14341 attcattccc aatattttgg taatattatc gatatttatt tcaggaaaaa tgatttgttc
    14401 ctgaataccg agtgtataat tgcctcttcc gtctaactta ctctcaattc ccttgaagtc
    14461 gcggatacga ggaagagcga cacgaacaag tctctccaag aactcgtaca tctgctcacg
    14521 acgtaatgtc accatcacac cgatcggcat cttcttacgc aacttaaagt tagagatatc
    14581 ctttttagat acggtagcga cagctttttg accggtaatc gtagacaact cgctgatagc
    14641 gatatcgatg atcttcttgt cagccgtagc catacctaat ccctgattaa tcacgatttt
    14701 cttcaaaaca ggtacctgca tcacggattt gtaaccgaac tccttcgtta aggcaggaac
    14761 aattctgtct tggtattctt tcttaagact ggcagtattg ctcattactt aatttcctcc
    14821 cctgattttt tagaataacg cactaaagca cccttctcat tcaacttacg gccgatacgt
    14881 gtagctttac cagatttcgg gtcaaccacg ttaaggttag aaagatgaat aggagcttcc
    14941 ttcttttcga ttcctccttg aggattcttc gcattaggct tggtatgctt tgataccaca
    15001 ttaatacctt cgacaatcgc acgattatct tttacaagta cctgtaaaac acgacctgtc
    15061 ttacctttgt cctcgccggc attaacaaat actatatcgc cttttttgat atgtaattta
    15121 ctcattactt taaattttac gagattaaag cacttcaggt gcaagtgata caattttcat
    15181 gtttgttgca cgaagctctc tggcaaccgg accgaagata cggctaccac ggatatcgcc
    15241 accggcattc aataatacgc aagcgttatc atcgaaacgg atataagaac catccggacg
    15301 gcggatctct ttcttagtac gaacgatgat agccttagaa acagcaccct tcttaacgtc
    15361 gctagctggg attacgcttt tgattgctac tacgatcaca tcacctacag tggcataacg
    15421 ctttctcgtt ccgcccaaaa cacggataca caaagcttcc ttagctccac tgttatctgc
    15481 tactactagt cttgattctt gttgtatcat cttacttagc cctttcgatt atttgaacta
    15541 atctccatct tttagtcttg ctcaaaggac gagtctccat aatctttacg gtatcgccaa
    15601 tgttgcattc gttattttcg tcgtgagcat gatatttctt cgtcttatta acgaactttc
    15661 cataaatggg gtgtttttcc ttccatttaa tggcaaccgt gatgctttta tccatcttgt
    15721 tgctcgttac cacgcccgtt ctttcttttc ttaaatttct agtttccatc aggctcaatt
    15781 atttgttgtt aagttctctc tggcgcaatt ctgttttcat gcgcgcaatc aatctgcgtt
    15841 gctgtttaat ctgagaagga ttatccatag gcgagatgct atggttaatc ttcttctgat
    15901 cataggccgc aacctctgca tctactctct ctagcaactc tttcgtgctt agttctctaa
    15961 tttctgcaat cttcataaca attacgcatt ttgattttgc atgtcataat cacgtctcac
    16021 aacaaacttg gttgtaaccg gaagtttttg tgcggcaagg cgcaacgctt ccttagcgat
    16081 atcaaaggga acaccttcga tctcgaaaat cagacgaccc ggagtaacag gcgcaacaaa
    16141 tccctcagga ttacctttac ctttacccat acgaacctct gcaggcttct tcgtgattgg
    16201 cttatccggg aagatacgaa cccaaacctg cccctgacgt tgcatataac gtgtaacggc
    16261 gatacgggca gcctcgatct gacgaccggt aatccattta ttctctaatg actttattcc
    16321 aaaagaaccg aaggccagct ggttgccacg ttgagcttcg cccttcatgc gacctttctg
    16381 ctgtcttctg aacttggttt tctttggttg taacatctct acttaaattc taacgtttaa
    16441 cgattagctc tttttctctt gaagttcttg tctctgttgc caccggcatt gtcgtttcta
    16501 cggcctgtct ccttggcagc agtgaaagaa ggagcaagat cgcgcttgcc ataaacctca
    16561 ccacggcaga tccaaacctt aacacccagc aaaccaactt ttgtcaaggc ctcagccaaa
    16621 gcatagtcga tatctgctct aagagtgtgc aacggagttc ttccttcctt atacatttcc
    16681 gaacgagcca tttcagcgcc attcaaacga ccagagattt gaatctttat accttcggcg
    16741 cccattctca tggtagaggc gatagccatc tttaccgcac gacgatatgc gattttacct
    16801 tcaagctgac gtgcgatgtt gtttgctacg ataacagcgt ccaattcagg tctcttcacc
    16861 tcgaagatgt tgatctgcac ttctttatca gtgatcttct tcaactcttc cttcaactta
    16921 tcaacttcct gaccaccttt accgatgatg atacccggac gtgacgtaca aacagtgatc
    16981 gtgatcaact taagcgtacg ttcaataacg atacgagata cactagcttt tgcaagacgg
    17041 gcattcaaat atttacggat tttgctatct tccagcaaag tatccccgta attcttaccg
    17101 ccataccaat tggaatccca accacggata attcctaaac gattactaat cggattaacc
    17161 ttttgtccca tctacaaatt aattttgact atcgttttta ctaagtgtat caacaaacag
    17221 agttacgtgg ttcgagcgtt tacgaattct gtaacctctt ccttgaggag ccggacgcat
    17281 tctcttcaac gtagtagcgc aatcaacgct gattgaagat acgcataact ctcctgcttc
    17341 tgctttacgt tcatttttct gttcccagtt tgcgattgct gaacgaagca atttttctac
    17401 tcttgctgca gcttccttgt tagaaaactt caaaacacca agcgcacgga atacttccat
    17461 accgcgaatc atgtctgcta ccaaacgcat cttacgagga gaggtaggaa cattgttcaa
    17521 cttcgcgaaa tacatggtct tttgggcttc ttttcttgct tcagctgata ttctttttct
    17581 agcacccatt ttattcgatt ctttttattt tcagattcct gaattcctgt tactaccgat
    17641 attatttctt cttgttaccg gcgtgaccgc ggaaagtacg tgtcggtgag aactctccca
    17701 acttgtggcc taccatattc tcggttacga aaacaggaat aaatttattt ccattatgaa
    17761 ctgcaatagt atggcctacg aaatcaggcg aaatcattga agctcttgcc catgtcttaa
    17821 ctacggcttt ctttcctgac tcattcattg ccagaacttt cttctcaagc tttacattaa
    17881 tatacgggcc tttttttagc gaacgactca tagtttactt aattaatcag attatttctt
    17941 tcttctttca ataatatact ttgaagaatg cttcttagga gctctagtct tcaagccctt
    18001 agcatataag ccattacggg atctaggatg acctccggaa gaacgacctt caccaccacc
    18061 cattgggtga tcaaccgggt tcataacaac accacggttg cgaggacgac gacctaacca
    18121 tctagagcga ccggccttac ctgatttttc aagagcatgg tctgaattgc caactgcgcc
    18181 aattgtagcc ttacaagccg caagaatctt tctagtttca ccagaaggca tcttaataat
    18241 cgcataagcg ccttcctttg aagtcagctg agcgaatgca cctgcggaac gtaccatttt
    18301 ggcaccctgt ccaggacgaa gctcaatatt gtgaataata gtaccaacgg gaatatttgc
    18361 cataggcaaa gtattaccta cctcaggagc ggcgtcgcta cctgaaacca ctgtttggcc
    18421 aacttccaat ccgttcggag cgatgatata gctctttgct ccgtccgcat aatacaacaa
    18481 agcgatacga gatgaacggt taggatcata ctcgatagac tttactgtcg caggaatgcc
    18541 atctttgttt ctcttgaaat cgataattct gtacttttgt ttgtgaccgc caccgatata
    18601 acgcattgtc atcttaccag tgttgttacg tccacctgta ctcttcttac ctactacaag
    18661 agacttctct ggtgtacttg cagtgatttt atcaaatgca ccaataactt tgtgtctctg
    18721 ccccggtgtc gtgggcttta atttacgtat tcccatttct ctttttagat attactaaag
    18781 aaatcaattg tttctccttc tttcaacgtt acgatcgctt tcttgaaagc agcttgcttg
    18841 ccgttgatga tacctgattt tgtataacgg cttttacgct ttccagagta gttgatggtg
    18901 ttaacatcaa ctactgtaac actgtacata tcctctacag ctttcttaat ctccaatttg
    18961 ttggcatcag gagaaacacg aaaaccatag cgattcggaa atttctctgt gatcgctgtt
    19021 tgtttctcag ttactatagg cttaataata attcccatta ttctactcct tatgctttaa
    19081 aattttgttc aacaacagcg actgaacttt ccgttaaaac caaattaaca gcgtttaaca
    19141 cagcgtatgt atttagttca gaagcagtta ttacacttgc cttctctaaa tttcgagcgg
    19201 acaaatatac taaattattc ttctccggta aaaccataag taacttttta tcagccactt
    19261 tcaagttttt agcaattgtt ataaattctt tagtcttagg agcttccatt gtgaaatcct
    19321 ctacgacaac aatcgcattg ttctttgcct tgtagctcaa tgctgactta cgagccaaag
    19381 attttacttt cttgttcagc ttgaactcat aatcacgagg cttcggaccg aatacacggc
    19441 caccaccaac caacaccgga gagttgatat caccacgacg tgcgccacca ccacctttct
    19501 gacggatcag cttacgtgta ctaccagata cttcgcttct ctctttagac ttatgcgttc
    19561 cctgacgttg atttgccaaa tactgcttta cgtccaagta aatagcatga tcgttgggtt
    19621 caatgccgaa gatcgcatcg ttcaaagtta cctttcttcc ggtatcttca cctttaatat
    19681 taaatacgct cagttccatt acttttcaat taataagatt gaaccttttg ctcctggaac
    19741 agatcccttt accaataaaa ggttgtgttc cggcattacc ttgatcactt gaagattctg
    19801 aacggttaca cgttcgttac ccatctggcc gcccattcgc atgcccttaa atacctttgc
    19861 ggggtaagaa caagcaccga tagaacccgg cttacgagca cggttatgct gaccgtgagt
    19921 agtctgacct acaccaccaa aaccatgacg ttttactaca ccttggaaac ctttaccttt
    19981 tgatgtaccc actacatcca cgaaacctgc gtcttccaag aaatctacag tgatcacgtc
    20041 acccaacttg tactcagttt cgaaattctt gaactcggcc aagtgtcttt gaggtgctac
    20101 accggctttc ttgaagtgac ccatctcagg ctgtgtcgtg tgcttctctt tcttctcttg
    20161 gaaacccaac tgtacagctt cgtagccatc tttctccaaa gtcttgatct gtgtaaccac
    20221 acaaggaccc acttcgataa cagtgcatgg aagatttttt ccctcggcac tgaaaacgga
    20281 tgtcattccg attttttttc ctaataatcc tggcatttca ctaattgtta aaaacttaca
    20341 ctttaatttc tacttctaca ccgctaggta attctagctt catcaaagcg tcaactgtct
    20401 tcgcagttga gctatagata tcgattaatc tcttataaga agagagttcg aactgctcac
    20461 gagatttctt gttaacgaaa gtagagcggt tcactgtaaa gatacgtttg tgcgtaggaa
    20521 gaggtatagg accgctaacg atagcacctg tagcctttac cgtctttacg atcttctcgg
    20581 cagacttgtc taccagagaa taatcgtaag acttcaattt aattctgatc ttttggctca
    20641 tatttattat atgtttctaa atattatttg atcaaatcaa cgcgaccttg cacctctgtc
    20701 aatacttgct tagcgataga agaggatact tgagcgtagt gtgagaactg cattgaagat
    20761 gtagcgcgac ctgaagtaat cgtacgcaaa gctgtcacat aaccgaatgt ctcagccaat
    20821 ggaaccttag ccttcacgat acgggctccc gtacggctag tctccatacc ctcaacttgt
    20881 ccacgacgct tgttcaagtc accgataacg tcacccatgc tctcttctgg agtaacaacc
    20941 tccatctgca tgatcggctc catcaataca ggacctgcct tggcggaagc gttcttgaac
    21001 gcttggatag cggcgatctc gaaagacaac tggtctgagt ctaccgggtg gaaagaacca
    21061 tcgatcaaag tcactttcag cttgtcaagc ggataacctg ccaacacacc gttcttcata
    21121 gccttctcga aacctttctg tacggacggg atgaattcct taggaatgtt accacccttc
    21181 acctcatcga tgaattgcaa agtaccctcg aagctctcgt cagccggctc catacgaacg
    21241 atgatatcag cgaacttacc acgacctcca gattgctttt tgtaaacctc gcgaagctca
    21301 accggctgcg tgatagcctc cttataagta acctgcggac ggccttggtt acattcaacc
    21361 ttgaactcac gacgcaaacg gtcgatgatg atatccaagt gaagctcacc cataccgcta
    21421 ataacggtct gacctgtctc ctcgtttgtc tgtacgcgga aagtaggatc ctcctcggcc
    21481 aacttagcca agcccatacc caacttatcc atgtctttct gagtcttagg ctctacagcg
    21541 ataccgataa ccggttccgg gaattccata gactccaatg tgatcggatg gttttcgtcg
    21601 caaagcgtat cacctgtacg gatatccttg aaaccaacac ctgctccgat atcaccacaa
    21661 ccaatcacct ccatcgggtt ctgcttgtta gagtgcatct ggaacaaacg ggagatacgc
    21721 tctttctttc cggaacgagt gttcaacaca taagaaccag cgttgataga acctgcgtat
    21781 acacggaaga agcacaaacg acctacatac gggtcggtag cgatcttaaa tgccaacgcc
    21841 gtcaatggct cctcgaacaa aggtttacga gtgattattt tatcaggatc tgaaggatcc
    21901 gtaccctcga tagccggagt atcttcagga gaaggcaaaa acgcgcaaac tgcatccaat
    21961 aaagtctgta cacctttgtt cttgaaagaa gaaccacaag tcatcgggtt gatctgcata
    22021 gccaacgtac ccttgcggat agcaaccatg atctcctctt ccgtgatcgt agaaggatca
    22081 tcgaagtatt tctccatgat agcgtcgtcg cactcagcca aagcctcaag catcttgtcg
    22141 cgccactcct cagcctcagc ttgcaagtct gccgggatct cctctacgct atactcggca
    22201 cccatagtct catcgtgcca gaagatagcc ttcatcttga tcaagtcgac aacacccttg
    22261 aaagtctcct cagctccgat agggatctgg atcggacaag gattagctcc taatacgtcc
    22321 ttcaattggc gtactacctc atagtagtta gcacccgagc ggtccatctt gttaacgtaa
    22381 ccgatacgag gtacattata tttatcagcc tgacgccata cagtctcaga ctggggctca
    22441 acaccaccta cggcacagaa tgtagcaaca gcaccatcca atacacgaag agaacgttca
    22501 acctcaaccg tgaagtcaac gtgtcccgga gtgtcaatca agttgatttt ataacggttg
    22561 cccaaatagt tccagaatgt agtcgtagca gcggaagtaa tcgtgatacc acgctcctgc
    22621 tcctgcgcca tccagtccat tgtagcagta ccatcatgag tctcaccgat cttgtgtgtc
    22681 aaacctgtgt aaaacaagat acgttcagaa gtcgttgtct taccagcgtc aatgtgagcc
    22741 atgataccga tgttcctagt gaacatcaat tgcttatcgt tgtttgccat attcttttta
    22801 ttgccttaaa aattaaaatc tgaagtgagc gaacgcacgg ttagcctcag ccatacggtg
    22861 catatcttct tttcttttga atgcgccacc ttggttattg aaagcatcta caatctctgc
    22921 agacaacttg tcagccatag tcttacctcc acgtttacga gcgaagataa taaggttctt
    22981 catagaaatt gactctttac gatccgggcg gatttcagta gggacttgga atgtagcacc
    23041 acctacacgg cgtgacttaa cttcgacttg aggagtaatg ttatcaagcg cagctttcca
    23101 aatttcgaga gcggactttt cctcgttagg caatttgccc ttaacggttt ccaaagcgga
    23161 atagaaaatt tcgaaggcag tatttttctt gccatcatac atcaaatggt taacgaatct
    23221 cgtaaccttt acatcaccga aaacaggatc cggaaggatc tgtcttttct ttggttttgc
    23281 ttttctcatt ttgttttcaa aaatttgttc ttgtcgttgg ttgcctttaa tttgtcttca
    23341 acggttccgc tgaaccattt actcaacctt atagcctatc caaataactc aaacctgttt
    23401 taatacttaa atttaaatct cagtttgaag gcatgtaatt aattacttct tcttaccttt
    23461 tgcggcagct gctgcttgac ccggtttcgg acgcttagct ccatatttgg aacgtctttg
    23521 cgtacggccg ttaacacccg ctgtatccaa cgtaccacgt acgatgtgat aacgcacacc
    23581 cggaaggtcc tttacacgac caccacgtac caatacgata gagtgctctt gcaagttgtg
    23641 tccttctccc ggaatatagg agttaacttc cttaccattt gtcaaacgta ctctcgctac
    23701 tttacgcatt gcagagttag gtttcttcgg agtcgtagtg taaacacgta cgcaaacgcc
    23761 acgtctttga ggacaagcgt ccaatgcggg tgatttaccc ttctccacca aagtttccct
    23821 tccttttcta actaattgct gaattgtagg catttctttc tttttttaaa ctttgaatgt
    23881 gttattatta tttatctaat cttttcctat ttcgagccgc aaagttacgc attattttcg
    23941 gacaatcaat aagttgtgcc tgtttttttc gtatactccg cactaaaaac ggtgcaaagg
    24001 tacatatttg ttcccgtttg gcaaggtagg ccctagccgt atttattaat atttaacatt
    24061 cactatcttt atttacctca ctggcacgta aagcgactgg tggcgggtgc cgatatcacg
    24121 caatttaccc gcctcgacaa attgatgcag gcggcggctg gccgtactgc tcgtcaggcc
    24181 gcaaagccgc tggaaggcga cacgggtcat atattcatgc tcggcaaaat aactcgcgag
    24241 caattggtcg atacgatcag gctccaattg gcgggaatgg gatttgtact tggctcgttc
    24301 cagcgtcatc gtcttcaagc tatctttcag ctctacctcg ggacggaaag ccacggactt
    24361 gaaacggatg gactccgcac gtatctcgtg cgtggattgt acggccgggc attgcaacgt
    24421 gacttgcaaa taccccaacc catcgatatg tacacgtttt ccttcacgca aatattccgc
    24481 tgtcacctcg cttaaagaga taagcacggc ggctacgtct gccggcgtga cggtacaccg
    24541 tccatggata cgtttggcca gatcatccgt atcgatcgtg ccggatgata cgatacgtgc
    24601 gtgaaaacga ggacgcttcg tgctgtcctt cgataccgga gtcttgtaaa agtcatattt
    24661 tgctgccata tatctagtat gagattaaaa ggttattcat cgaaacatcg tatgctatta
    24721 gtcatttcac aagggtgata tgatcttttc acctatgtga aacgatcgtt tcatgattgt
    24781 gatacgttct tttcacatag gtgaaaagat tataagcact taacaaaggt actacatcca
    24841 taccacttaa acaatagttt tccctagtat ttcgcacaga ttacttttat ttcaaatgac
    24901 aatataaaca tttggaaaaa cgcaagttaa cagcttatat ccgcaaaatg aaacagtaaa
    24961 aacaacctct aaaacatagc gtcatgaaaa ctgtattgga ttttttaggc caattatggc
    25021 ttcgcttctt aaaaccggac gggtcgatca ccgtaccaca cccaaacgaa ggtaaagcga
    25081 aacgatcgag cgacagcaac tctatccttc aaaagagtct ggagactttc ctccaagaac
    25141 ggatcgaatt ccacttcaac ttgttgagcg aggagactga atatcgatac aaacaattgg
    25201 aaacggatcg cttctatccg gtgacgcaac gtgacctaaa tagcatttgc atggaggcaa
    25261 gacggacggg gatcgattgc agggatcggg atgtgaatcg tttcgtatat tcaaaagaag
    25321 taaaagagta tcatcctttc cggcaatata tggagtggtt acccgaatgg gacgggaaag
    25381 accgggtaag cgatctggca cgacgggtct cctcagaacc gttatgggtg gaagggtttc
    25441 atcgctggat gctcgccttg gcctcgcaat ggatgggttc ggaccgaatg cacgcaaata
    25501 gcttggctcc cattttagtc agcgagcgtc aaggatgtca gaagtctacc ttttgcaagt
    25561 cgctgatgcc ttcttcgcta gtccgctatt acacggatag cgtagacctt agcggctcga
    25621 cgcaaatgga gcagaagctt ggattgttcg gactcatcaa cctcgatgag ttcaaccggt
    25681 tgtccgaccg taaaatggct ttactgaaaa attggatgca gatggccgga atgaacgtac
    25741 gcaaggcaca cgccaagcat ttccccccta ccccgcctag cctcatttat tggcactacg
    25801 aaccagaaga acctattaag cgaccccact ggaagccgcc gtttcctatg cgtggaggtg
    25861 caaagcaaga ttaattgcga aggtatcgag catgatcaaa tctacgccca gctgaaaaac
    25921 gagttacaaa aaggagagcg ccattggttc acctccgtaa aggaggaggc gatcatgcga
    25981 tcgaatgagg ctttctataa acgtccgatc gaggaagatg tgttccacgc ctgcttccgg
    26041 gccgcatgtc cgggagacct aaatgtaaat gcagccgtga aacctatgtc atcgaaacca
    26101 tccctagcac ttaaatcttc tctccagctc ctcatctgtc agcatggaga taatcgtctt
    26161 tccatccggg gtcaggttcg agtccgaaca agagaacagg gaggcgatca gatgatccat
    26221 ctcttccaag gataaggatt tgccgggacg gatagcggcg gctttggcta aagacaaggc
    26281 gatggcctcg cagatcttct catgcactgc gcatccggtc tcgatcgccc ggtccacgat
    26341 atcctttacc aaatttaccg gatcaaggtt ctctataccg gcgggcaggc cattgatcgc
    26401 gtaattgtca tttcccagat tgctcagatc aaagccgacg aagcacaaat cctccaataa
    26461 ggaaggcagt acagccgcct cagcagcggt aaactctacg atctccggga ataagacttg
    26521 ttgggataca ccttgttgct gacggatatt cgacaggtat tggtcaaaca agatacgcac
    26581 atgcgcacga tgctggtcaa taatcgccag acccgatttc aaggatgtca cgatatatcg
    26641 ccctttatat tgatagcaag gattgcttac ctccgtaaac agtttttccg gatccgaagc
    26701 ctcggccggc aattcctcga tcggggcatc ctcgaaagtc tcggactccc gttggacagc
    26761 cactcggtcg ttctcaaacc cttgatataa tttagaccaa tcgaattccg gttttttata
    26821 ggaagtagtg tcaaacggat tataactgga atccacttgc actttcgggg ccttataagt
    26881 actaggctca cttttcttga ccgggttgta aacaggaata tcgatcgcgt cctccacatc
    26941 gaaatcaatc gtagggatag cgctcgattt agccaacgcc tcccgggtag cggccatcaa
    27001 gatctgccag atcggttgct cgttctcaaa cttaatctcc gtctttgtcg gatggatatt
    27061 gacatcgatc gaggagggat ccaacgtgaa ataaacaaaa taattcggca tatccccggc
    27121 aggaatcaat tgctcatagg cctgcatgat cgccttatgg aaataaggat gcttcatata
    27181 acgaccattc acaaaaaaaa actgcaatgc ccctcgcttc ttcgccgagt ccggacgccc
    27241 cacgaaaccg gaaatagtca ccatggaact ttgggcatcc agagagagca acttctggtt
    27301 taaactctta ccatatatat taatgatgcg ctgacgtaac cccgactcgg gcagattgaa
    27361 tatctccgca tcattatgat aaagagacat acccacctgc ggattcacca aggcgattcg
    27421 ctcgaactca ttgatgatat tccggaattc cgtctcattc gacttcaaga atttccggcg
    27481 ggcgggaaca ttaaagaaaa gattctttac cgagaagata cttccctcgt tacaagcctc
    27541 cggctcgata ctctccagat tggaacccgc gatggatagg caagtgccaa gctcggtccc
    27601 tctagcccgg gtacgcaact ctatatgggc gacagcggcg atagaggcca atgcctcacc
    27661 tcggaaaccc atcgtatgca aagagaataa atcctcggcc gtagaaatct tagaagtagc
    27721 gtgccgctca aaagccatgc gagcatccgt ctcggacata cctttcccgt catcgatcac
    27781 ctgtatcaat gtcttacccg catccttaat gttcacttgg atattggaag cgccagcgtc
    27841 caccgcattc tcgaccaact ctttaacgac agaggccgga cgttgaatca cctctcccgc
    27901 cgcgatttga ttggcgatat ggtccggaag taaatgaatg atatcgctca ttaccagaac
    27961 aaataccaaa agaaagcagc caagaccgcc aaggccaccg ccagtttcac attcttatac
    28021 ctacgagccc gggaatcctc gcctcgcccc acgcttttct tcagatgcga ggtaccttca
    28081 atgaaagttc ccttgatatg cggcttatat tcctccaacg gctcctctac acccatttca
    28141 cgtttgacct tgcttatacg ttcctccaag gcttccttat gggggtccca ataaataggc
    28201 ttatgatcaa attgacgcgg cttgcgcatg ttataaaacg agaaaagtgc catagcttta
    28261 cctattaatt atgaatacga cgctaatgta cgaatttatt gcttcttttc ggagcatctt
    28321 gagcttttct tttcacgacc tgataaatat catccttgtc tttaggacgg atataatcaa
    28381 accaataaaa gtctttcaag tatttctggt cgggcttcaa atcaggaata ggggtcatcg
    28441 tacctgttgg agtcggccag attttcagtt tatccaactt attgtctttt agccagatcg
    28501 taaggaaacc gcttttggtc tcgttcatgc cgaccatcga accgtccttc tccaagggga
    28561 aaaatataga ttcggcgttg cccgacacat cgatctgatt cacgacctgt ccctcgaaat
    28621 aagccttcaa gtcatttccc tttaattgat tgaatgcggt agaatcgatt tgctgtattg
    28681 cgaaagcgaa ttgcttcacg tgagcgaaat cgatcgagct atcattcata aatatcaaga
    28741 tcgtatcccc atagatctga tactgttcat tccaaacgat agggtccgta tacatatata
    28801 atatagagtc tcttgtatta aactgcatcg aatcgcaaac accttgcata tccgtccgat
    28861 agaaacggac gccgtaataa gcttttactt cccggtaaag ggagtccacc gtagtcatct
    28921 tcaaggtatc accatgcaga aacaatgtat ccccttggct gaattccaag aaacgggcgc
    28981 tatccgtagc gaaagcatac tcgctcttct cattgtaaaa gccatattgg ccttccagca
    29041 tgacatgctg cgccgtgtct tgcagactca tattaccgaa cgcttcccca aaacccagtt
    29101 cccggttgta ggcgatagag tcgcccgtca agatacggtc gccggaaacc acctgagaac
    29161 gatccaatag caaagaggta ttattcacgg tatcgtacca acctctggaa gaatagatcg
    29221 tgccgctatc cgagacgatt atggatggtc cgaggatcgt ggcgatcttc gagtccgtat
    29281 tataatgcaa ggtatcggaa tacaacgtga attgctcatt ctccagacgg acgctatcat
    29341 tgaagatagc caatttcgta ctaggcgaat attgcccata aaaagaagag agctgattca
    29401 aggaatcgac aatcagacct ccgtcgaaat aatatccgat atccgggatt cgctcatagt
    29461 tcaagctatc cgtaaacagg gtaacctgcc cattctccat gcggacattc tcccgcaaat
    29521 aagcgatctg ggtatttcca tcgtaaaaca ggtaatttcc atacacgaac aaggtatccc
    29581 cttgttccat ccggacatta ctaaacgctt ccaaggaatt ggtctgctca aagaaatatg
    29641 cgctatcgca atacatatac gaactatcat ggcgaaaaca aacatcacca ttcagtactt
    29701 gagcctcggc gttcctctcc ttatcgaacg aaagcgtatt cgcatgctcc aaaaagacct
    29761 tcgtcttctt gggagcgaca ctatctttgg cggctaccac cgtgctatct tgcgtttgcg
    29821 caaatacgcc aaccgataaa gcacacgata agagcgctag aaataacctg ttaattagtc
    29881 tcattcctta atccaacccg gatatttgaa atcacaattc ctccaaccgt cactaatacg
    29941 cacgtaggtt gatttttgtt tcttcgtgat ccagtcgttc aataattcct cacgtttctt
    30001 agcctctacg atcgctttca aagcttggaa gtcatcggcc aaattcgcct tatgtccttc
    30061 cgtccgagct ttcagcttaa caatagctac tacctctttc tgcttgttcg tcaacatggt
    30121 aaaaggcttg gagatctctc cgactttcat gccatatacc accttaccga tttcctgcgg
    30181 aagttcttgc atctcgaact taggggttcc catattgctg ctctcgtaat cttggtttac
    30241 catcaaaccc ttattattac gtgtatcctt gtcataagag acgaatgtag cggcttcctc
    30301 aaacgtgaac ttattcgcct gcaaatcatt gtacaatgaa tccagacgag tggtagcatc
    30361 cgccaactcc ttatcggaaa ccttcggttt caataagata tggcggcagt tgatacggtc
    30421 tccacgcttc tcgatcaatt ggatgatatg gtaaccatac tccgtctgta cgatctggga
    30481 gacacgtttc gggtctttca agttgaacgc aacgttcgcg aactccggca acagctgtgt
    30541 cttgctcatg aaacctaact cccctcctcg agacgccgaa cccggatctt ccgagtacaa
    30601 acgagccaac gtagagaatt ccatcttacc ggaattaact tgctccgtga aatcacgtaa
    30661 gcgggccttg atggcgtctg tttcctcaaa cggaatcttc ggttccaagg taacgatttg
    30721 cacctctaca gtcgtaggga tgttcggcag gctatcctga gacaactggc tgaaatattt
    30781 acgcacctcg gaaggtgtca gcttgatctc gccgatcaat tgatgctgca tctgttgcac
    30841 tacctgctgc tcccgcacca tctccttacg ctcatccttg atctgggaaa atttcttacc
    30901 gaaatattcc tccaatttct cgcgagaccc gatttggttc acagccatgt tcatccattg
    30961 atccacgctc tggatcactt ggttctcgtt cacggtaata ctatcgatct tagcttgatt
    31021 cagatatagt ttctgtatcg ccatctgctc cgggatcacg caatacgggt cgccatccaa
    31081 acggaccccc tcgttttgat tatacaaacg ctgcgtctca atatccgaac gtaaaatagc
    31141 gtcatctcct accacccaca caatttcatc gatcacattg tcttgcgcca ttacaatgca
    31201 agaacaacag gcaagaaaga atacacttaa aatctttttc atcatgtcta cccatttata
    31261 aaattagaga tcacggctcg gaatggaatt ccacgtcacc gctccggatc gcatcgttat
    31321 ataactcgtc ttcaaatttt ttcaagaatt caacttttcg ttggttgacc agcatttccg
    31381 tgacgtgcga actggcataa tcatatggct ccacactgcc ggaaggtaaa tattccttga
    31441 tattcaacag ataacaataa ctgctatccg ccacctcaac atacttattc gccttcagaa
    31501 acgcattcgg attcgacaca tggatcggta tattatccat tacctcatcg aaatcaaccc
    31561 atttgtcgta aaagtactca taaatcgtgg cattttgcac actatacttc tcaatttttt
    31621 ctaaagaggc cacatctgtg gatttgtacc actttttgac atcggtaagt cccggggcat
    31681 caaccgggat tttcaagaat aatcccttga tcaagccttt atccaagata aactttttct
    31741 ggttttcctc gtaatagttt aatttatcac tttcccggat atcagttttc agcttctcct
    31801 ccaccaatcg ttcctgataa cggtaacgaa ccaaggaacg cctgtactcc tctaccaatt
    31861 tatcgacctc ctctttctca tcccctaagt tacgcaaagc cacatcgtac accaatacat
    31921 cctttaccca tttcttggta aagccctcgg ccagcaacag actatctgcg gaggaaatcc
    31981 cccggggtat tagcttattc acctccgaac gatttagggt acgtcctttc acgctaacca
    32041 agacatccgt agtatcagct ggctgagaac ctttacaggc acccaacaac acaacgaacg
    32101 ttaggaacat gaagactatc ctcatatcta tctttatttt atttctttag tttcttcaat
    32161 aatttccagt tgacagtcac cggatatttt ttattcaaat ccgcaatcca cttcgcttcc
    32221 aacaccttct gctgggcgga gggtttgctc cagatctccc ggttgctgac ctcaaacaac
    32281 agaatcccat cccggtactc ctgcatcaaa tgagggatct ccggatgttt tgtctccaga
    32341 ttcttacgct cggcggtcgt tacgatatcg cggataaaca aatcatagat ctcttgcata
    32401 aaatcacccg catacgtttt tgtcgagaac ggacaacgtt ggatataata agcgaactcc
    32461 gcttgcggga aatcctttcc atccaattgc ataagcgtct tgttcatatc cttcgctttc
    32521 tcataaaacg cctcgtccgt ggggaaacaa tcattacata acgcttgcag ctccgcatag
    32581 gcttccggat agaaaacgta tccgtattct tttttcatac gatcgtcgaa agctttatat
    32641 aactcgaagt tacgttcacc ctgccccata cgtctcgaca aagctttttc ctcttcctca
    32701 aacgaagggc gtcccttctt atcgatcaac ttaatgatat ggtaaccaaa acgagtttcc
    32761 accacctcgg ataaatcacc cggcttgctc aacgcaaaag cggcttgctc aaaaggctgg
    32821 accatctcgc ctaccccaaa ccaaggtaat actccctctt tcttagcgga agcagcatcc
    32881 ccagaatatt ctttcgctaa ctcgccaaaa tcagctccct cttgtacttg cttatagata
    32941 gcttgcgctt ttgccagaaa agccgatgag tcctgaatag cggaatcttt cgggaaggcg
    33001 atcaagatat gagcgacatg tatccgcccc ggattgggtt tacgactatg gacttttatc
    33061 aaatgaaatc ctaatttcgt gcgaaccggt tcagacacca cgccaatcgg caaggaatag
    33121 gcggcatcct caaacacttt tagggattgc atcgggagca agcaacgtac atattcgcaa
    33181 gcgacatgct ccttatcctt ctcggccaaa gcttttccga ctgtttccat atcctctcct
    33241 ttctggagac gttcgtatac tcgcatggct tcttgatata cagctaccgt atctttggag
    33301 accgtcttct ccggcaaacg gaataagatg tgggtcaact ctaccgagtg atccccacgg
    33361 tcatataccg cacgggcagc cgctttctca ccctccttat ccgacatata gctatcgatc
    33421 aactgagccc ggtatccatc cagctcactt ttgaatgagg atgtctggtc gatccctaaa
    33481 gattccgcct ccgctacttt tagcttaaaa tttttaaata gctcgacata gtttttgacg
    33541 gactttgtat tcgataaatc cacctctcca ttcttctccg cgataaaaat aaattcagat
    33601 aaaggcactt gttttccagc gaccgtcata acgaccgaat cggatgcggt ttgagcgtta
    33661 actgtcacac aagcgaatac ccctaatgaa ataagtaact ttttcatcaa aaattctttt
    33721 accatagcac gaatatacat tacaaaaata acactaatct aacggagagc cgacaagaaa
    33781 agtatgctat cccattaaat tagtgttttt tataaaacgt aaaacttgta ttactattca
    33841 ccgcggctat aattcggagc ctcttgcgtg atcgctacgt catgcggatg gctctcttgc
    33901 acacctgcgt tggtgattcg agtaaaacga gctttatgca actcctcgat attatgagcc
    33961 ccgcaataac ccattcccgc acgtaaacca cctaccattt ggtaaatgac ctcatacaaa
    34021 gaacccttaa acggaacacg ggcagcgatt ccctccggaa ccagcttctt cacgtcgtcc
    34081 tccacatctt ggaaataccg atccttggac cccttttgca tagcttccaa cgaccccatt
    34141 ccacggtaag acttaaactt tcggccattg aagataatcg tatcgcccgg cgactcctct
    34201 acacccgcca acagagatcc catcatcacg gaagatccac cagcggcgat cgccttcacg
    34261 atatcaccgg agtaacgcaa gccaccgtcg gcgatcaaag gcacaccagt tccttccaac
    34321 gccttcgcca catcgtaaat agccgacaac tggggaacac ccacaccagc gatcacacga
    34381 gttgtacaaa tcgaacccgg accgatacct accttcacgg cgtccgcccc ggcttccact
    34441 aaatatttag cagcctcgcc cgtagcgata ttaccgacca cacaatcaat atgcggatat
    34501 tgcgccttaa tctgtttcaa gacatccacc acaccttttg agtgaccatg tgccgtgtcg
    34561 atcaccaaag catccacccc ggcatccacc aaagcggcta cacgctcgaa ggtattgaac
    34621 gtaacgccta caccggcagc tacacgcaaa cgacctttcg aatccttgca agccttcggt
    34681 ttatctttcg ctttcgttat atctttatag gtaatcaagc cgatcaactt attatggcta
    34741 tcgaccaccg gtaacttctc gatcttatgt tcctgaagga tctgagcggc ggcctccata
    34801 tccgtagatt gtccggttac gaccaaattc tctttcgtca tcacctcgtc gatagaacgg
    34861 ttcatgtcct tctcgaaacg caagtcacgg tttgtcacga tacctaccaa atacccgcct
    34921 tcatccacca cgggaatacc gccaatctta tattcagcca tcattgccaa ggcatccgcc
    34981 acacgcttgc ccttcgtgat agtcaccgga tcatagatca ttccattctc cgcacgttta
    35041 acggtctgga cctgctttgc ctgctcggcg atcgtcatgt ttttatgaat cacaccaata
    35101 cctccctcac gggcgatagc gatagccaac ttggcctcgg taaccgtatc catagcggcc
    35161 gacaccatcg gtatattcaa tgtgatatta cgtgaaaact ttgtcgtgag atcgacatta
    35221 cgaggaagaa cttccgaata agctgggatt aacaatacat cgtcaaacgt taacccatcc
    35281 ataactaccc tgtctgcaat aaatgacata gaacttatgc tttaaaaatt attgcgcgca
    35341 aatatacgac ttttcacgca ataaatcgat acgggagaaa ttaaaaattc gattcggaag
    35401 aaaataaact ttcatccgaa cgaaaacaaa attccttccg aaggaaaaat aaatctcttt
    35461 cggaaggaac aataagcttc tttatttgtt ttttctttag agtggaaccg ggccaccctc
    35521 ccattagttt gccatttcag acaagaactt gatacggacc aagcgaatct cctcttccgt
    35581 atagtcaccg cctaattcct caatggcgtc ttccagaccg tcggtctccg aatccttgaa
    35641 atactcgtaa atatcctcga tatgatcctc atccatcaca tcattcaaga aataatcgat
    35701 attgatacgt gtaccggaat atacgatcgc ctcgatctca tccaaaagct cggtgaactc
    35761 aagtccgtta gtcaacgcga tctcgtccag cgccacctta cggtcgatcc gctgaatgat
    35821 tgagaccttc aacttggact tattagcgac cgtacgtacg cgcaaatcct ccggacgctc
    35881 aatctcgttc tcctctacat gtttcttgat caactcaatg aactccttgc cataacgttt
    35941 cgccttacca gcgcccactc ccgggatatt ctgcaactcg tccaacgtga tcggataagt
    36001 agtagccata gcctccaaag agggatcttg gaaaatcacg aaaggcggaa cttccaaccg
    36061 cttggataat ttcttacgca aatccttcat catggaataa agaaccgggt ctaccgcaca
    36121 agaggcgccc ccacgaaccg gaacttcctc ttcctcttcc tcgaattcat tgtcctcggt
    36181 aatcttgaac gataccggct tcttcatgaa ctccttacct ttttccgtga ttttcagcaa
    36241 accataattc tcaatatcct tcgctaaata gccagcgatt aaagcctgac gaataacggc
    36301 gttccaagtt ttatcatcct cgtcctgtcc ggaaccgaag acctctaatt cattgtgctt
    36361 gtaattttgg atttcggagg tttcgttacc taccaaaata tttacgatat aatctgcctt
    36421 aaacttttct ttcaacgtac tgataacctc cagtaccgcg cttaacaatt ccttcgcttc
    36481 cacctgcttc tttgggttca aacaattatc acaattacca caattatctt ccaggtattc
    36541 ctcaccgaaa taatgcaata gcacttttct ccggcagacg gaagtctcgg cataggctgc
    36601 agtctctaaa agcaactgtt tgccgatttc ctgttcggcc acgggctttc cttgcatgaa
    36661 tttctccaat ttttgcaagt ccttataagc atagaaagcg atacattggc cttctccgcc
    36721 atccctaccg gcacgaccgg tttcctggta ataaccttct aggctcttcg ggatatcgta
    36781 atgaatcaca taacggacat ccggcttgtc gatacccata ccgaaagcga tcgtagccac
    36841 gatcacatcc gcctgttcca tcaggaaggc atcctgattg gcggaacgta cttgcgaatc
    36901 cattcccgca tggtaaggca acgcctttat cccgttggct ttcaagatgt cggcaaattc
    36961 ctccaccttt ttacggctca aacaatatac gatacccgat ttaccctcgt tggctttaat
    37021 atacttaatg atctcgcggt ctatattcgt tcctttcgga cgaacctcat aatacaaatt
    37081 agagcggttg aaggatgatt taaagactgt agcgtctatc atacccagat tcttctggat
    37141 atcgtgctgc accttaggtg tagcggtagc ggtcagagcg attaacggac gtttaccgat
    37201 ctcattgata atcggacgga ttcttcgata ttccggacgg aaatcatgtc cccattccga
    37261 gatacaatgc gcctcgtcca ccgcatagaa agagatcttt acctgacgca gaaaatccac
    37321 gttctcttcc ttggtcaagg actccggtgc tacatacagc aacttggtac gtcctgataa
    37381 tatatccgat ttcacctggt cgatagccga cttattcaaa gaggaattga taaaatgggc
    37441 gaccccatct tcctcactga aattccgcat cgcgtccacc tgattcttca tcaaagcgat
    37501 caacggagat atcacgatcg cggttccttc cattagtatg gatggtaatt gataacaaag
    37561 agatttacct ccccccgtcg gcattaatac aaaagtatcc ttcccggcca gcacgttctc
    37621 aataatagcc ttctggttcc ccttaaaggt accgaagcca aagtgccgat ttagctcttc
    37681 tgttaaatga tccttctttg ccatacttcg tattatttat agtaaaccgc ctacgtttac
    37741 gcgacctgta aacggttcac gtccgatttt tcaaatttct ctttcgcata ctccaacgtt
    37801 acatggagtt cctttacttt ttgagatggc atactgtaca tagcgtccat catcacggct
    37861 tctacgattg aacgtaaccc acgggcaccc agcttaaact caagcgcctt atccacgata
    37921 aactcataga ctttctcatc gaacgtcagc ttaatgccat ccatatcgaa caatttgacg
    37981 tattgcttga taatggagtt cttcggctcg gtcaagatgt tacgaagcgt atcacgatcc
    38041 agcggattca gatacgtgag gataggtaaa cgaccgataa tctccgggat caagccaaac
    38101 gacttcaaat cagtcggggt gatgtatttc agtaaattat tccggtctac ggtagccgta
    38161 tccaaactag ccgaataacc gaccacacgg gtatttaagc gttgagcgat cttcttctcg
    38221 attccatcga aagcaccacc gcaaacgaac aggatattct tcgtatccac cgcaatcatc
    38281 ttttgctccg gatgcttacg tcccccctga ggaggcacat tcacgatcga tccttctaga
    38341 agtttcagca aaccttgctg tacaccctca ccgctgacat cccgagtgat agacggatta
    38401 tcgctcttac gtgcgatctt atcgatctca tcgatgaaga cgataccccg ttgggccgcc
    38461 tccacatcat aatccgccgc ttgcaatagc cgggtcaaga tactctcaat atcctccccc
    38521 acgtaacctg cctcggtaag taccgtagcg tccacgatag cgaacgggac atgcaataac
    38581 ttagcgatcg tacgggctaa caaagtcttg cccgtaccgg tagcgcccac catgataata
    38641 ttagatttct caatctctac atcatcggcg gtaacctttt gaagtaaacg cttgtaatgg
    38701 ttgtacaccg ataccgacag ataacgcttc gcgtcatcct gcccgatcac gtactgatcc
    38761 aagaaagtct tgatatcttc cggtttaggc agatctttct gcttcaaacc aaaagaagtt
    38821 ttcttacctc ctgtctgctc ctttacgatc tcatacgcct gccgggcaca atcatcgcaa
    38881 atacaaccag agatcccatt gataagcaaa ttaacatcac ggctactcct gccgcaaaac
    38941 gtacatgtat cgcctgttgt tttggccata gtttcttatt gttgtttttg ttatttacgt
    39001 gttaaaacat cgtcgatcat gccatacttt ttcgcttcct ccgcggtcat ccagaaatca
    39061 cggtcgccat cgcgctcgat ctcctcatag ggtctacctg aatgatccga gattatggtg
    39121 tacagttctt tcttaacctt caagatctcg cgagcggtaa tctcgatgtc tgaagcctgt
    39181 ccttgtacgc cgccaagcgg ttgatggatc attacacggg agtgcttcaa gccgaaacgt
    39241 tttcccttgg ttcccgccac caataagaca gacgccatag aggcggccat acccgtacaa
    39301 atcgtagata cgtcgctgga gataaactgc atcgtgtcat aaatgccgta gcccgcatat
    39361 acagagccac ccggcgaatt gatataaata gagatatcct ttccgggatc actggaatcc
    39421 agatacaaca actgcgcttg aatcacgtta gcggtataat catccacttg cgtgcccaag
    39481 aaaataatac ggtccatcat caaccgagag aagacatcca tttgagcgac attcagctgt
    39541 cgttcctcta taattgtcgg ggagatatag ctactggaga tgttcatata actatccaga
    39601 gccgtaccac tcatacctaa atgctttgta gcatactttc taaaatcttc catattttct
    39661 cctatctttt atttaccgag aagacgtaaa aagggatttc cctctgtgac ttaacggaaa
    39721 aacaaagtta taaataaatt tctgaaagaa acaatttatt tcgctatccg ctaagatatt
    39781 tttagagaga aatccctttt ttgatataaa acaacctcct aagaggccga gtaaagatct
    39841 ttttattcaa aaagtttgtt gaactcgtca gcggttacct ccttaacatc aagttccact
    39901 tgctctttca accaagcagc caatttctcc tcaaccgcac ggtcgatgat gttctgaagt
    39961 gtttgcttat ttttcaacat gtctttagcg tagttgtcaa gtacgtcctc aggtacagac
    40021 aacatgccgt attgagcgaa ctgagcctta gccacacgtt tagcgaagtt ctcgatgtca
    40081 gcgtcctcaa ccttcaagcc gttcttctta accaagttct ccttgatcaa ctgatatttc
    40141 aaatcctgaa ggatctgagg gaagtcctcg tcgatcttct ctttcgtatt cttctcgtta
    40201 gcggcaagca accaacgttt caataaatcg tcagcgaaat tcaactcgcc agctctctca
    40261 accaacatat cacgagtatc cgtcaagaac ttgaagtcac tctgaggagc gaattgctct
    40321 gccaaagctt ccttgatctt gttcttgaat tcttcctcgc tggtaaccac gttctcgcca
    40381 aataccttgt cgaacaactc ttggttcatc tctgcgtctt tatgacgggt gatctccttg
    40441 atctcaaagc taaagtcgcc tgtagtctca gccactttct ctttatcgat cttcaagaaa
    40501 gaagcgatct ctgcctcagc accctcgtaa gccttattcg ggttgaatac cactacggca
    40561 tttactttag caccgataaa tttagctttt tcttcctcat ccttgatata cataggcatc
    40621 aagacagcat cctcaacaac gataccacct tctttcgggg caccattctc aagctcggct
    40681 accgtacctt ttaccatatc tttttcctca acctcgtcta ccttgtcgta agaaccgaag
    40741 tttgagcgat aagcgtttac ttggttattt agcatttctt catcgatagc gacttgatag
    40801 aacggaagtt tatcgttctt gctcaactcg atattgatct ccggagccaa agccacgtca
    40861 aaacagaatt cgaaatcctc ttccttatcg aaatccaacg gcttttgctc agtctcgtta
    40921 ggcatcggct cgcctaagat atgcaaatcg ttctcacgga tatacttgaa cagattctca
    40981 gaaactaatt tgtttatctc ctctaccagc acgtgctttc cgtacatttt tttaaccatg
    41041 cccataggaa ccatgccctt acggaaaccc ggtacattgg ctttctgacg aaggctacgc
    41101 aggctcttgt ctacctgatc agcatagtca gctttcacta tttctaattt cacgataccg
    41161 cttacggcat cattgttttt aagcgaaacg ttcattctga atgatttatt taattaatag
    41221 tcgtatcgaa ttttaggtcg caaaattaga cttattcttt taatcgtgca aattttgatc
    41281 tgtttttatt cttttgttta tatttggcgg caattattta ccctttgaat gaatcattat
    41341 gagaataaaa ggaatatatg ctacccgtcc ggcgataatc caacttttga tcctcttgct
    41401 attcttattg gctggagcca ttttatcatc tattatatcc acgggcttat tacttgcgac
    41461 ccacggttta caggctgata taacccaaga cgctaattta atgaggctca ttcagttcat
    41521 ctcggcgatc tgtacctttt tgctaccatc tatcgccatg gcttggatat gtagtgacaa
    41581 tccctgccat tatctatcag tcaagaaaat cacagacggc aggatctgga ttctcacctt
    41641 agtttgcgtg ttcttatttt ctccggttat caatttgcta ggattgctca acaagcagat
    41701 ggagttaccc gcgtttatgg ctcctatcga ggaatggatg cgggcgcaag aaaccctcgc
    41761 cgaacaactg acgacgatcc tgttatccag cgatagcgtt tgggtaatcc tggccaacct
    41821 tatcgttatc gccgttacgg ccgggataac cgaggagttc ctgttcagag gagccttgca
    41881 acgagtgatc gggaaatgga cctccaaccc tcatacgatc atatgggtcg ccgccatact
    41941 atttagcgcc ttccatttac aattttacgg attcttgccc cggatgatac tcggagccta
    42001 tttcggctat ctactctatt ggagcaagag catctggata ccggtgttcg cccactttgt
    42061 caataatgct ttcgccgtaa tagggatgtc ggacagtcgt ctcaaggata acgagtttat
    42121 cacaggcgat attcccgccg agcatctttt ggacttttgt cttatcgccg ccttatcttt
    42181 cctgctgttc atactggtaa acaggcgatt gaaacgactg ctataagtct ttcttacgca
    42241 gcacaaagtc ttttcccaaa tatttctcgc gcacgatctc gttctcggct agttgttcgg
    42301 cggttccttg gaaaaggact tttccctcga acaggagata ggcccggtca caaatactca
    42361 atgtctcgta cacattgtgg tcggtaatca agattccgat attcttatgt ttcaagcgag
    42421 ccacgattgt ctggatatct tgtacggcga tcgggtctac accggcgaaa ggctcatcca
    42481 acataatgaa cttcggatcg atcgccagac agcgggcaat ctccgcacga cgccgctctc
    42541 cacccgaaag ctggtctccc aagtttttac gaaccttatt caaaccgaac tctgaaatca
    42601 aactttccag tttctctttt tggtactcaa tgctacgtcc cgtcatctcc aagaccgagc
    42661 ggatattatc ttccaccgtc attttccgga aaatcgaagc ctcttgcgcc agatagccaa
    42721 tgccgttgcg agcccgctta tagaccggga atttcgtaat ctccatgtca ttcaagaaga
    42781 tcttaccctc gttaggagtg accaaaccta ctgtcatata aaaggtggtc gtctttcccg
    42841 ctccgttcgg accaagcaaa ccaacgatct ccccctgttt cacgttaatc gatacatgat
    42901 tcacgaccgt acgagtccta tatttcttta ccaagtcctc cgtacggagc accattcgtt
    42961 gttcgtctga cataagctac ttaaaaattt aacgcgaatg tacgtgataa tccgcagatc
    43021 tacatcacat acattcgcaa aaaagcgata agagaattta ataactccac tcagatcgcc
    43081 actcgatcac gggttgctcc ccctcgaatc ggataggaag ccagatataa cgtccgtcta
    43141 tagcgttctc cggagtccaa cgatctccca tataaataaa gcgatccgca tggccgggta
    43201 caggcaatac gtacgtgctc tgagaataaa acgacacctc cgagttctct cccctaaacg
    43261 gattttccaa ttccttccaa ggtccccaaa tcgaggaagc gaccgccgat cgtcccgcat
    43321 tcggagccca gcccgtacag ccggacataa tcaaataata tttccccttc tgtttgaaca
    43381 aggctggagc ttccatgaaa cgccccggga agaaacgggc gtacttaccg gaataactcg
    43441 tataatcatc ggtcagctgc gatatatgca aggtactatt ctcttccgag gaataaatat
    43501 gataagcgat gccatcgtca tccacgaaaa ggttcatatc cctagccatt tgtccggaga
    43561 tttggtcacg ccccaataaa ttcaagctat ccggatgggc aggtaactct ccaccgctaa
    43621 aacgtagatc tgcggaaagc gtacaaggtt gcttatgtag ttcctgtaca ttaaccggcc
    43681 aaaaaccggc attcggacgg aaagcgttta cgaacgagta aggccccgcc acgtttttac
    43741 tgacagccac tccactcaat gctcccgaat agccagcacc tctcggctct aaatgaaacc
    43801 acattacata ttgatcattc tttttattat aaatcacttt cggacgctcc aacacgcatc
    43861 ccttaacaat atggctcgtc gtatcatccg gcacgaccga taaggcgatt ccctcgtctt
    43921 tccaattata taaatctttc gacgaatagc aatgaacgcc tacttgagcc agatttccag
    43981 ccgagccctc cgttttatgt tcaccaaacc aataataagt atccccaacc cgtagaatac
    44041 cgccaccatg agcgtttata tgtacccctt tatcatccgg ccaaacttcc cccggcttaa
    44101 aagaaagatc cttccgcagg caagccacac ataaacacag caagccgatc actcctaaaa
    44161 gaattcgctt cataaaagta ttttttagta tttaagaaaa caaacatagt taaaaaagag
    44221 ggatgtggca aactttaata ccataggatt tacaaataaa accaatcttg tttctaagat
    44281 gttatatggt tattagtgga ttttacgcta tctttgcaaa ttgaaatcag aaatttatca
    44341 agataaaaat gaataaagca ttacacagaa tgggtgagta taccctactg atgatgaaga
    44401 gtataacact tccagaccgg tggagtatgt tctttaagca attgatcaaa gagatataca
    44461 agctaggcgt ggattctctt tggattgtca taatcatctc ggtctttatc ggtacggtta
    44521 tcgccatcca gatctccttg aatatcagtt cccccttgat tcctaagttt acgatcggct
    44581 ataccacccg tgagattatc ttgctggaat tctcttcctc tatcatggca ctaatcctag
    44641 cgggtaaagt aggcagcaat atcgcctccg agatcggaac catgcgagtc actgagcaga
    44701 tagacgccat ggaaatcatg ggtgttaatt cagccaactt cctgatcctt ccgaaaatgc
    44761 tcggtttgat gatctttatt ccggtattgg ttatcttcag tatgttcacc ggtatcatgg
    44821 gcggcatatt cgccagttac tcaacgagta cgggaatgac tccttcctcg ttcgagtacg
    44881 gtttgcaatt ctacttcaac gagttttaca tttggtattc tattatcaaa tccgtagtat
    44941 atgcgttcat catctcatcc atcgctgcct attttggcta taacgtaaag ggaggcgccc
    45001 tagaggtagg taaggcaagt acgaatgccg tggtcatgag cagtatcatg attttacttg
    45061 ccgacgtaat attaacccat ttaatgctta cttaaaaatg atcgaagtta agaatataac
    45121 gaagtctttc gatggacgtg tcgtcttgaa agatataagt acgacgttcg aggatggtaa
    45181 gacgaatctg atcatcggac gaagcggttc gggtaaaacg gtaatgatca agaatatcat
    45241 cgggttaatg aaacctgata ccggacagat attatacgac ggtagagact tgatcacgat
    45301 gaacaagcat gagttaaata tgctgcgtcg ggaaatgggt atgttgttcc aaggttccgc
    45361 tttattcgac agcatgacag taatggaaaa cgtaatgttt cctttagata tgttctctaa
    45421 agactcaacg aaagagcgca ggaaacgtgc ggaattctgt ttggaacgtg taaacctgtc
    45481 cgaggctgga catctatatc cttccgagat cagtggaggt atgatgaaac gtgccgccat
    45541 cgcaagagcg atctccctaa atcctaaata cctgttctgc gatgagccga actccggact
    45601 agaccccaag acttctctat tgattgatga tttgattcac gacattacgg tggagtacaa
    45661 tatgacgacc gttatcaata cccacgacat gaactccgtg atgaatattg gtgataatat
    45721 catctttatt aaggaaggcg tgaaggaatg gcaaggaaca aaagagcagg taatcacctc
    45781 taataaccaa gcgttgaacg atttcatctt tgcgtccgac ctgttcagga aagtaaaaga
    45841 agtagaaatg ctccaagagg aagggtaagt taacatactt ggcaaagtat cttaacttca
    45901 tcagctaagt atcttaactt aaatggcaaa gtatcttaac atacttcgcc atttaagcca
    45961 gcttactttt tccacttatt ttttatagac caaacacgtc cttgatctta tctgcataat
    46021 ccaatttctc ccatgtgaat aactccacat cacaagtaac cggcttctgc aaataacggg
    46081 aagagaatgt cttcgtcacc gtctggggtt tgcgtcccat atggccataa gaagcggtct
    46141 cgaaataaat cgggttacgc aatttcaaac gctcctcgat cgctttcgga cgcatatcga
    46201 agatatccca gatcttcgcg gcgatctctc cgtctgtcat attcaccttc gcacggccaa
    46261 aagtattcac gaaaatattc atcggtttag ccacaccgat cgcataagac acctgtacca
    46321 gcatctcatc cgccacaccg gcggcaacca tattcttagc gatatgacga gcggcataag
    46381 cagccgaacg gtctacctta gaagggtcct ttccagagaa agcaccaccg ccatgagcac
    46441 ctttgccacc gtatgtatcc acgatgatct tacggccggt caaaccggta tcaccgtgag
    46501 gaccaccgat cacgaactta ccggtcgggt tcacgtgata aatgatatta tcattaaaca
    46561 aagcctgtac atgagccgga tattgagcct tcacacgagg tatcaatatc ttcttcacgt
    46621 ctaaggcgat cctcttttgc atagcctcat ccgcttcctt ctgtgaaata cctttcggac
    46681 cgataaactc atcatgctgc gtggatacca caatcgtatc gatacgcaac ggcttaccgt
    46741 tatcatcgta ttcaatcgta acctgactct tagcgtccgg acgcaaataa ggcatcaaat
    46801 ccggttcttc cttacggatc ttcgccaatt cccataataa actatgagat aagtccaacg
    46861 ccaaaggcat ataattctca gtctcattag tagcataacc gaacatcata ccttggtcgc
    46921 cggcaccctg ctcataggga tccgcacgct ctacgccacg gttgatgtcg ccactctgct
    46981 catggataga agagaacaca ccacatgatt tcgcttcaaa ctggtactcg cttttcgtgt
    47041 aaccaatctt ctcgatcacg ccacgtgcca cttcctgcac atccacatac gcacttgatt
    47101 taacttctcc agccaagaca acctgtccgg ttgtaacaag ggtttcgcaa gcaactttcg
    47161 aattcttgtc atacgccaag aactcatcca gcaaagcatc cgatatttga tcggctactt
    47221 tatcggggtg cccttcagac accgattcgg aggtgaataa ataactcatc gttttaaatt
    47281 gaaaattgag aattgaaaat tgagaattag gggataaacc acaggtcgca attgacaatg
    47341 ctcgttagtt attaatctat gactgaattg aacttggaag gatttttctg ccggacggca
    47401 acgaaaagga tatgttttta gcattttttc ccgtggttgc aagcaataca aatctatcca
    47461 cgtcaattca ttcgcaaaga tacgcaataa ttgagaattg aaagttgaaa attgaaaatt
    47521 atttcttctt tttggaatta cgtaaggctt ttttatattt aaaaccggcc ttccatttcg
    47581 ctgaatcaga gccatgtgtc cctttcaaga aatcagagaa cttgattttc ttaccattcg
    47641 aatcttccgc ttcgcctttc gctttcttga agacgatccc ttgcgtcatc gctttattaa
    47701 tttctttatt cataactcaa atctcgtagt tcataattaa aacttataat tcggataaaa
    47761 gttcacgcat cgtcttgcca aacacaggat gtttcaccaa cggagctact tctgccaacg
    47821 gttccataac aaacgaccgt ttgtgcatca gagggtgcgg tagcgtcagc cgctccgtat
    47881 gcaggatttg ctcatccacc attaacagat cgatatcgat gatacggtca tgatacgcac
    47941 cgtcactttt ttcgatacgt cccatctcga tctcgatcaa acgggtagcg tctaataatt
    48001 ccatagggga aagttccgtc gtcataacga tcacggcgtt caagaaagtg ttgtccgatt
    48061 caaatcccca aggctccgtc tcatacatat cagaaagggc aagaacatct cccacccttt
    48121 cagccaacag cgccgccgct gtcaccaaat ttcctcgttt attacctacg ttcgtaccta
    48181 atccaaggta agctgtcgcc atagaaaccg gattaaagga ttagcatagc gtcgccgtaa
    48241 gcaccgaaac gatatttctc tttcaaagcg atatcgtaag cgtccatgat caactcataa
    48301 ccaccgaaag aagctgtcat catcaataat gtagacaacg gcatgtggaa atttgtcacc
    48361 atgctggtag ccacgctgaa atcatacgga gggaagataa acttattcgt ccagccctcg
    48421 aactctttca gatgaccatc cgtacttacg gccgtctcga tcgcacgcat cacggaagtt
    48481 ccgaccgcac aaaccttgtg cccctcatcc tttcccttgt tcacgatatc cactacatcg
    48541 gcatttacga ccatttgctc agaatccatt ttatgctttg tcaaatcttc cacgtcgatc
    48601 tcacggaaat tacccaagcc cgaatgcaat gtcaagaaag cgaactggca atccttgatc
    48661 tccaaacgtt tcatcaactc acggctaaaa tgcaatcccg cagcaggagc cacaaccgca
    48721 ccttcttccg cggcgaaaat attctgataa cgatcctcgt cttccggttc cacctcacgt
    48781 tcgatatact taggcagcgg agtctcgccc aaggcataca aagccttctt aaactcgtcg
    48841 tggttcccgt catataagaa acggagcgta cgaccacgcg aagtcgtatt atcaattacc
    48901 tccgcgacca tggaatcatc ctcgccaaag tataacttat taccgatacg gatcttacga
    48961 gccggatcca ccaatacgtc ccacaaacgt aagtcctcgt tcagctcgcg caacaagaac
    49021 acctcgatac gcgcccctgt tttctccttg ttaccgtaca agcgagcggg gaaaactttc
    49081 gtgttattaa agataaacac gtcacctttt ccataatagt ctagaatatc cttgaattcg
    49141 cggtgctcga tctcacccgt atcacgatga acgaccatca acctcgactc atctctgttc
    49201 ttcgccggat gtaaagcgat taattccgac ggtaagttaa atttgaattt cgaaagcttc
    49261 ataatgcact ctatttattt ttcttcttct atttttacca cattctgctc taagaaatca
    49321 tcgatctcct ccggagacat acacatatcc aaggttacct ctccgatgcg agtccgttcc
    49381 aagccaatca aatgagcgcc ggaatccaag gccttcccga tatcacgagc caacgcacga
    49441 atataggtac ctttgctaca taccacccgt atctttataa caggcaaatc acactccagc
    49501 aactccagtt cgtctataac caatgtcttg gattttagtt caacctcctc tcctttccga
    49561 gctagctcat aagcacgctt accttccacc ttgcaagcgg agaacaccgg gggaatctgt
    49621 tggatcgtac ccacgaatgt ctttaaaacc tcctccacga gctcacgggt tatatgttcc
    49681 gtgggataca cggcgtctat ctctttctcc aaatcgaaag acggggtagt ctctcccaac
    49741 ttcaacgtag cgatatactc cttcgtctgg tattgaaact catcgattcg cttcgtagcc
    49801 cttccggtac aaacgatcat cacacctgta gccaagggat ccagtgtccc cgcatgtcca
    49861 actttaatct tctttacctt cagtttccga cttagcttat agcgaaattt gttaactagg
    49921 tcaaaagaag tccacgttag cggtttatta aaatataaaa tctctccagc tataaaatcc
    49981 attctttatt taagtaatgt acaagcaatt gtcaccaatc ccgcaatcgc acaatagata
    50041 gcgaaataaa tcagtttccc ctttttcacg atgttgatca tccatttaca ggccacgcaa
    50101 ccggaaacaa aagcggccat gaaacctacc gctaatgata acgcaggaat gtccccagcc
    50161 acatcttcac ctttcaccat cttcatcaca tccagcaacg cctctcctaa gatcggagga
    50221 attaccatca agaaagagaa ctgggccagt ttcgccttat tatttcccaa taacaaaccg
    50281 gtagcgatcg ttgatccgga acgagacaaa cccggcatca cggcgcaagc ctgagccaga
    50341 ccgataataa aagcgtcttt catcgagatc gactctttct ggcgtggttt ggcataatac
    50401 gaaaatgcca gcaaagccgc cgtcaatagc agcatacaac caacgaccaa taaacccgat
    50461 ccaaagattt gttctaccgt atctttaaag aataccccaa cgatcccgat cggaatcatg
    50521 gaaatcaaga tattgatcac atacttcgtc tctgcgttca tctgaaattt aaataaacca
    50581 cggaatatcc aatcgatttc cttccataaa accactaacg tactgaatac ggtcgccaca
    50641 tgcacgacga tcgtaaacgc aagattctcc tctccctcta taccaaacaa agctgagcca
    50701 atcgctaaat gaccgctact gctcaccggc agatattcgg tcaatccctg tacgataccc
    50761 agtatcaagg cctcaaacca actcattctg ttacttcttt atctttgcta ttcttcaaga
    50821 ttccaaaaat catcatcacg aaaccgataa ccgtaaccac cggagctacc acgatacggc
    50881 gggcgctgaa tatatcggga ttgaacgtat tatccccgga acctccacca ctcatcaata
    50941 tgaaaccaag cacgatgcag gcaaccgcta ccgcaatcag tataaaattc tcttttccga
    51001 aagcaaaatc tcttttagcc atctttctca actctttatt attcgtacat taaatataat
    51061 acaacttatc gacccccatc cgcaaatatt tattcacggc aaaaatggtt gcgatcacgg
    51121 acaagacaat acctaaagca aacactgcca cataaaccaa taataatgtt tgcatatcca
    51181 atatctggat aaaacctttc aattcatttt gcaaataata taacgctccg gttagcatca
    51241 atattgccaa gatagaggcg aaaatgccac ttactatgtt atatttcaca aaaggcctac
    51301 gtataaagcc ggaagtagcc cccactagct tcatcgtatg aatcaagaat cgtttggaat
    51361 aaatcaacag gcgaatcgta ttactgatca acacgaacga gataatcatc agtaccgccg
    51421 ccaaggtaag caggatcaag cccaaccgct tcatattatt atggactatc tccatcatat
    51481 cctttcggta aagcagctcc gagaccgacg tatagtttct aatcttcttc tctatcactt
    51541 ggaggctatc ggggttggcg tactccgaat gcagtttcac ctcaatcgag gcctgtaaag
    51601 ggttaaagcc taagaagatt tccggattct cgcccagttc ttcctccaac tcttttgcgg
    51661 cttgctcttt cgatatatac tcggttgatt ttataaaagg aagagcatcc aagctcttct
    51721 gcattttctt tatctcagtt tctttttggt tatctttcag cacgatggag aaagataagt
    51781 tctctttcac ataaacggag agtttattac ccaacatccc tatcaataga atgagtccta
    51841 gcaagaatag taccaaggag atactaataa cagacgtaag ccgggagtta aagaaagaaa
    51901 cagaactaac ttttttattt tcagccatca gactctcact tattaacgtt aaataaatta
    51961 aggagatgcg tacagagaac acacctccca attttcttgc aaaagaacga ataaaataag
    52021 taagccgaaa gggttttaga atatttaacc tctacaactc taacaaaggc tattcgtaca
    52081 tatacaatga taaaaaagaa gaccgccgga actgagtatt cctagcggcc ttccccaaca
    52141 ttaaagactc aagggttagt ttcttaaaat aaggttgtta gcgaacgttt actttcactg
    52201 ttatatgctt gccattctcg ttgatctcta tcagatagat tcctgtcgat accgggatgc
    52261 gggtaggtcc gataattgag tcgccataca ggctaactcc agtcaccgct atgatacgga
    52321 tcgagattgg acgggccgga tgaacggtta tcgcacctcg ctcgcaatag atttgatgat
    52381 cgtcgatgat ttgctcgata cctaccgtac cggagacagt taccacacaa gacgccgtct
    52441 tgtttccatc atcggtagcc acggtaatct tgcaagtacc gatcttcaat gcggtaacga
    52501 caccatccgc gtcaacagta gccaccgtct cgtcgctgct actccaagag acggttttca
    52561 tagtggcgtt attaggggta actttctctt gcaaggcaaa agattcacct acggccaatg
    52621 ccttggacgt gatattcaaa gaaactcccg taacagccac atctgttccc ggaggtgtag
    52681 aaaccggctt gaactctgct ataatagcca aggacttatc gacttcaatc tctacaggcg
    52741 aagtcgtata cttctcttcg cctatttgaa taacggccaa ttcataatcc ggattggctt
    52801 ctgtctcaat ggttagctta gtcgctttcg ccacagcggt tccactcgtt atctcggtct
    52861 tctcgccctc acctttcaac atatagactt tcaaagaacc attttccggt tgagcgaacg
    52921 tgacaactaa cgcatccgaa cttttcaccg taacctccgc attcgtagtc gcatcctcat
    52981 aattcggatc atacgacgtg aagatcactt cctttttctg gctatcgccg ggtttcaata
    53041 tagctgacgc atcagcccat tcaaatttac cggatatggt agttccatcg gcacctttcg
    53101 caacaccacc ggataatagg gattccgaca aagactgacc ttccgtgatc gtagatgcgg
    53161 taggagctac tacctctacg accttcgctt tctttatcac taatttcttg gttgcctcga
    53221 aagatcgcca gttctcatcc ccggtacgtg ttacagtcac aagataagta cctgcgttca
    53281 atggggtagc gaccgatcca tccgtatttg aatatttaat atttacatct gtcggataac
    53341 taccgctcaa aatgtctttc aattccacta gctttacgga accattataa acaaactcca
    53401 aatctgaagt attcgccgtt attttaggtt tatccacaaa attcggggcg tatgtcgcat
    53461 cagccaccaa agtaaccgtt atctcagggt tctctctatc ggtgcttgag acattttcac
    53521 cccaagaatc aaaacacaga ttctcgctag gagccaccgc ccgcaacttt aaaaccgtat
    53581 tctccggaat tttagaataa tcgctaataa ccaagcctcc attcgtaacc tccgtatttg
    53641 aggcacttaa agaaaacgtt tttacttcac caaccggcat tgaataatct accgattcat
    53701 aattactctt gtcaagtggg gtaaagcgca gaatatttac ctgatccatt gtcgggcttc
    53761 cagtcacgtt cgcacgaagc gccgattttt gtttggaagg attccattcc acatcctcga
    53821 agtcttgagt aagtttagcg tcaacctttt cataattatc ccctcctata gtcggtactt
    53881 ccagcaatgc cataccagcc ttcttgataa tcagctcggc agttacatcc acggctttaa
    53941 ataaatcatc ctcgccacgg gtaatccgaa ctttataagt tccggccgat ttaggattct
    54001 ctgtcatttc taccccactc cgggaatatg cgaccttaaa gtccaaaccg gaatagcccg
    54061 taatcttaac ctcgaaattc cggtattgct tattatagac taccgtttgc gtcgtcttat
    54121 caatcagcga agccaaatct ttcttctcca cataattagc ggtaacaacc atagggccgg
    54181 aaacggtgaa tacgtctcta tccttgatct cggaagagtt caccatcata ttcataaaac
    54241 gatatcccgt ttccgtctca acagaagcgg tcaattgagt catataagga accttagaac
    54301 cggaagccac ctctttaccg gccttatctt tcaatacgac tttacccgca ttggggatat
    54361 tcaacgccga ggttatttga tatttcacca attggaaact tgcgctcacc gtaacatctc
    54421 cggtcccaac cataaatgag ccatcagcct cattataatt cgcaccttcc actttcacgg
    54481 aagccagctc atagccataa tccgcatttc ctatcacctt cactttcaca ccttcagaga
    54541 tagcctcacc gggagtaaca ggcgccttcg tatccacctc gatcagattc acgctaccat
    54601 tcttcaactc cccaaccttt accaaatgtt tatccggttc tttttgaagg agatcggccg
    54661 atatatcagc ggcttgtatc aaagtataag aaccgttatt caccaaagcc ccgttcacct
    54721 tcacggactg aaccatatag cccggatccg gagtcgccgt gatagtcaat aaggttccct
    54781 gcaaaaactc agcaccattc tttacctcca cgccattcgc gaagaccttc aaggaaccat
    54841 tcatcggatt cgtaaacgtc acgccataaa cgatcgaatc gaaacgggct acgatatcca
    54901 agttcgtatt cgcttgcaac tcccgtgtag ccgatgtatt cccatcactc caaccggcaa
    54961 accggtaatt cttatccgcg acggctgtcg ctttcaaaac cgagcctctc gcgtatttat
    55021 catttgcggt acgcccctcc aagatgacag taccgaaatt accggcggta acattcatag
    55081 aataaacagg aattacgttc aaggttataa acgtatcttt agccgcatag agaacaggat
    55141 cattcggttc gaatatcaag tcgtactttt tcttatccgg agaagcgatc tcgttcggag
    55201 ttttccagat aaatgatccg gaagaagttc catcgatcaa ggtacacgcc gataaagcct
    55261 gtccttcctc aatacgaccc ggagtaggta acaccaaact ctccacctct ttcttgctct
    55321 ccaccactaa cgtaaccgta tcagagaggc tacggtatgt caagtcctcc gcacggctca
    55381 aacgggcctt ataagaaccc acggccagcg tggaaggcaa tgtcgtaacc caagccgtac
    55441 cgctcaattg atattcgatc ttgatatcct ctacagcgct tgttaccgtg accggcttga
    55501 tggagccgac cgtctggaca aggttgttag ccacgaacct caccgtatcc ttggagacga
    55561 acgcaaaggt atagctatcg ccactcatca gattaggagt cgtgtacgtg taagaggtat
    55621 ttccattagc atacgttccc ttgatcttcg agatatccac gtccgaagag gcttgcttaa
    55681 tagcccctag cctatagttg gcattcgata cgatcgagaa aatgacgggc ttaccgtaag
    55741 cgatctcacc accgctcatg atgtccttgt tatccatctt ggcggtaacc gtgccctgtc
    55801 caccatcgac agcgtaagcc aaggtattgg cattacggat cgtaaacgtt ttagaggaat
    55861 cctctaacgc ggcatactcc atggtctccg gactaaataa gacgatctta taagctccga
    55921 ctatctgcgg taatgtggaa gtctccgaac catcggccgc acgatatcga accgcttgtc
    55981 ccgctatttc cggcgtaaac ttaataaccg gcaaattctt cccggccacg atctcgtctt
    56041 ttgtcgccga agaacctgtt acactcacgg aaatcgtttt cttcgcggcg aaacctaccg
    56101 ataaggtcgt agaggcagtt aacgaggcgg tcgtataggt ataagagatg gtgttatcct
    56161 tattaagcgc gccttttggc aaggctgata ccgcagttcc attcacaaca atcttattca
    56221 atagaaatcc ggggttagcg ataattgtaa atacggcagg ttggccgtta atgatctcgc
    56281 taccgcttgc catgtccgta gagcccatct tggcggtaac cgtaccttgt ccggccgttt
    56341 ccacgttata atttaataca ttcgctttag ataccgtaaa cttcatgttc tcatccttca
    56401 aggcggcata ttccgcagtc tcgggactgg tcgcgacgat cgtgtaaaca ccatccgccg
    56461 caggaagttt atcggataaa gctccggaag cgttcttata ttgaaccttc tgccccgcta
    56521 tcgtattggg ggtaaatgtg ataaccggaa gattcttacc agccaaaacc tcatccttcg
    56581 tggcagataa tggattggct gttacagata cggttttctt cgcggcaaat cgcacgtcaa
    56641 taaccgtaga agcggtcaac gccgatgtcg tataatccgc ataggaagtc tcattcgtag
    56701 aagaattaaa agttcctttc ggcaaagtca cctcattatt atctacggta agtctgctca
    56761 acacataacc gggcttggag gcaatcttca atacggctgg cttattataa acgatctcat
    56821 caccactggc gataatggag ccatccatag aagcggttac agatccttgc gcctcctcaa
    56881 acgagtaaga aagcgtatgg ggcggttgta ccttgaatag aatctccttg tttatggcga
    56941 cttgcgtatc agtctccgac ttggttacga caacataata aagtccagcc ttttcgggta
    57001 gctcatccgt caaagcagca gagccatcct ccctgtattg tactttatac cccgtaataa
    57061 ccgggtcaaa agtaaccttg ggcaaattca ccttcgctct tatctcatcc aaggtggcat
    57121 actcaggaga gatcgtgacc gtcacctgct ctttcgcctt gaacaccgcc ttgatttccg
    57181 tactaccggt taaagcggtg gaagtatagg aataagtggt cgtattatca ttttgaaaag
    57241 taccgctcgg caacgtgcca atagtagccg tattcatcgt tatatccgac aggacatatc
    57301 cgggcttcgc cgtgatcgtg aaaacgggtt tactattata tgccaccttg gaacctgtgg
    57361 ctaccgtact ggttatggtt ccttgatccg tattcgccga gctataattc aatgtcacct
    57421 tgaacgtcgg aagatccggg gcggaacgta aatctgaatc ttgcgcatgt acctgtgcca
    57481 tcgcgatgac agcaaggaat atcgctaata tactcttttt catgtttatc tttgttttaa
    57541 tcgttattta acccttacta attgaccgtt cacggcatag atgcccgaag gaaccatgat
    57601 ccgctgtccg tccgtaacct cgctacgata agcgaccttg ccattcattc cgatgatcac
    57661 cacgtccata ggctccggcg tgtgaatcac gatagcgcca cgatcggtag tcacgtaata
    57721 accatctacc ggctcgatcg tctggttacc cgtaaccacg ccatcgccga tacgtaaaga
    57781 gcgaagcgta ctcaatgtct tggcgtctgt caagacaaaa ctttggaaag gcttgatctc
    57841 cgggtttgcc tcttgctcga aagaggttcc atccgctgtc aatatataag cggattgttt
    57901 caaggtaatc gtaaatgtat tcggattcga gcacatcaag aaagtacctg tttcagttgg
    57961 agcggcagct tcttccaagg tcttgaattc gaaagctcct tcggaagaga tcgtataggt
    58021 atcgccatta gccgcccaaa gaccagccat gccaaaagca ctctcatcca ccacgaactc
    58081 cggagtcttg ttatccttca gcctagcgaa ccagatacca ttatcaacat tttgagcact
    58141 tggagccgag atctcctcct ccgtagagtt cttgatcacg gcagaggtaa atggcattcc
    58201 aaacgccttc catcccgtag cagacaaaag tggagcgaaa cgaagagacc gagccgtcaa
    58261 cttcccttcc gtagcggtaa ataccacttg tgcatcctct tccatcatca ctgtatctaa
    58321 agccataggc accgagacag tcagtgtcgc tccatttaga atattcacct gtcgatcttg
    58381 aaaagatgtg gcccacgtag tatcactttt tatgtcaatg gctactacac attcttttat
    58441 agaaaatgac tgcgcacctt gattcaacca ataaaccctt ttaaatggat tagcaatagc
    58501 atatgcttta gctgtatttt cctctattac taaacgacca tccttgcaat taaaaataac
    58561 accatccggg atagtataag gctcccatgt gtccacatcc ggaaagaaat taggctttgc
    58621 cgcatttaaa gaattaagcg tttctgccat agtcgtatca ggaatcagta ttatatctcc
    58681 cgcataggca atgccttcat ggtaatatgt actcccatac aattctccaa aatcgattgc
    58741 tgttactata gagaccgccg cattcctaaa tgaaccatcc ggtttattaa tgattacaca
    58801 aggtttccct ttctgatctt gaaattgcac atcagtgcct tccaccatga ttacattatt
    58861 atattcatca ggattcatac cataacccac tatagttggg ttctttatgt tatcagtagt
    58921 tgagacaatt gtttttcctt tcaatataat cttattatca caaggagtag gagtaaaact
    58981 accatttatt ttaatcggag tcattgccat tgtctcttgt tcatcaaact tattcccgat
    59041 ataagaatct tcaatcacaa tctcgttatt ggaagctccc actgtagaat tatttgttga
    59101 tatcgctata gccgcaaaac tatcggaaac acccttattt tttgtcttac ctgttaagat
    59161 actcccgccc gaaacatgaa cgttcatatc tgaggtctca tacaaataga gagcaccgta
    59221 tcctacgatg ttcgatttat tctttattgt caatttttga tcgccggcgt tattagcata
    59281 aatacaataa tggttattta gcaagattgt cgtactatct accgtcactg gcgttttttt
    59341 atggtgaata tatacaccaa attgattcga accgttcacc tgtccatcaa tctttgtgtt
    59401 aacaagagag acatccgtca gttctccatc aataagaact cctgcttgtg cgttagccgc
    59461 caaatttatt gtagtatttt caacatgtac agtccccttt gccgttgctc ccagaagaat
    59521 cgcattttgt aatacttccg caggatttgg gttcttacga tcaccatagc cttgtgtatt
    59581 attattcata atacaattat ctatcaacaa atccgcatta ccggttacct ctataattgg
    59641 agtacatttt ccagaggtaa ctttcgttgg cgtataatcg atactcaatc cttttatttt
    59701 aacatcggta gcagtattat tcgcagagcc attaatcaag atcgcgcctt ttataatagt
    59761 cttgtcccgc ccagttcctt gaattgtgat agatttatct aatggtagag tcattggtaa
    59821 agtatattct ccttcaggaa aaatcacttt atcctcctct tctaaaatca tattcgtcaa
    59881 taatacgtct aaattggatg ccgcattgtt caaagtcccg ttcttatgaa tcgaaacaat
    59941 gcaaggcttc tcgttttcag tcttaaactc aacattttca acccctaaaa cctccaaatt
    60001 tgttcctgca tcatcaaaaa ataatgtagg agcatatttg tcattcttgg attggattaa
    60061 agccttagag ccatcggtgg atgtaaacgt ccaagtaccg gaagtattct tacggacatc
    60121 agccacacac atataggtga tggggctatc tatcggtgct ttattctctg aaacgataga
    60181 acttttagag tccatcgtca tagtcaaatt ttgacaatta tccaaaacga cagttccaaa
    60241 tccatcactt ggcccatttt ggtaagaacg tccatacaaa tgagtattag agatcgctac
    60301 attatgcggg taggcttcat ttactaaatc acctcttaga aaaagtgcgg cccaagcagt
    60361 tacactggaa ttgtcgatag ttatatttac ggcatttgtg taccccgctt ggttgatggc
    60421 aaatattgca taataattca catctactac agaattcctt atattataag ttaccggatt
    60481 agtattatca gttcctccca cccatgagca aatgccgatc acgtaaggat ataaaccttt
    60541 agctgaaggc ccctccatct tacttcctat aaaattgagt gtatggcctc caccatcacg
    60601 aaatgcaagt cctctttcaa aaccctcaga catatacata cgggagttga taaagtttac
    60661 ggtgttctca tctacagtta attgagacac tataccgaaa caagccccgg aaccactatc
    60721 acccgttccc cgcccctcta tcgttatctt actctcactg aaagacactg tcgttttaga
    60781 ggatttaata tcgacaactc ctcgtccagt cgatgttttt gctgttagat gtaccttttg
    60841 gaaagacaca ttccctccgt ttgttagctc aatatctacc ggagacttaa ttgtaactgt
    60901 tgaggtatca ccttcaccaa tgatagccaa tgatgatttg gtgatagaat aaggagctgc
    60961 attagccgag tattcccctt caggtaacaa tatgatcaca ctatctaatg aagataatgc
    61021 cgcatcagac aatgctgctt ccaagtttgc cttgtaaatg ggtgaaccag cagatgatcc
    61081 atcaccacct gttcctacag ccactttgta gtatgtaggg atcatttgtc cccaccccac
    61141 acttgcaccc accataaaga cggcgaacaa aaaaagtagt cttcttttca tacgattaat
    61201 ttttataagt tagtaatatt caattattta aaacatttac cctatattca taaactctgt
    61261 agcttccagc acatcagtct tctcataatc atcatttaca agcagttatg cgaaatcatc
    61321 ggttataaaa cgactagtct aaacgatcat tttattctgg cgttttattg aattcaacgc
    61381 ataagcgtcc atatttacgt ttatgcgttg ataatcaatt tttaaaagtt tctctggatt
    61441 ttgttttatt caaaaatata gcctatcttt aacgcctaga ataaacgatc gtttagacta
    61501 ggcgttttta tctattacag aatacttata gatcaaatat ttttacgtaa acaaaatttt
    61561 ctaccataaa aactttatat catcacaagc tataagattc tcttcttaaa gcatgtggaa
    61621 tagcataact aaccaaatat cagactgcaa ctatacataa ttgagataaa aggaattcta
    61681 caatattgat tttatgaaaa catctacaat atctaccact acgccatgta tgctttataa
    61741 atcaaagcat tacatatagg ttgtagatag cctgacatct acaattatca ttcaacatct
    61801 accacttata cttgacattg atactttttc tttgcattgg ataagaaaac gtgttatttt
    61861 tgaaagacat ttcccttagg ggaacaaaga gtttctccta gagaaaacta aagtttcttc
    61921 tagggaaaac taaagtttcg taagcacaaa acaaaagttt tccgctatga aaacttttgt
    61981 tttatgccta aaaaactata aatacctatt attcaataca ttaaatcagt acacaaggta
    62041 tacaaataac caagcaggca acctgttggc ataccctcgc agaacgagta atgtggttag
    62101 cgaatagtga acggctgcat ttagtggttg aaaagcagta aatagtggta gatgcaagct
    62161 gatagtggta gatgtttatt atctaccacc attcaacaaa tttcttataa ttagatactt
    62221 atatagataa tggcagatat ggtagatgat ttagtttttt catttcatac tcaaggtacc
    62281 actccagaaa aatatcagta caatgcatta agaacccaaa agaacggcta ataaaaatca
    62341 aggtaagctg tcgctattat gaaaagggaa gctataaaca taatttacgt acgtgtacta
    62401 taaaataata cgcaagaaaa aaccacagtt ccgtaggaac taaatcctta ctatctctct
    62461 ctttcgatat ggcaaagatg ggaagtaata agaatcaaat ggttacaaaa atgacatttc
    62521 ttgttagata aatgacataa cagatccgca atcaatccta aaccactctc ctctaatatc
    62581 ctatacataa attacccatt gagttcctac ggtacttaat aactttataa catatagcct
    62641 atggagtata tctaataatg tattagttaa tctgaatcta tcagacttat cgtatgtagt
    62701 taacattatc tattcaatta tgaacaaatg aaaagtatga aaagtaaaat gagaacttgg
    62761 aatgtggcga tgggatcatt gtctttgctc ttcctctgcg tatcgccggc attggctatc
    62821 gctacaaatc catcacaaga gaacccgtat acggagcgga acgatgattc cgtaactcaa
    62881 cagagaacaa gaaaagtgac aggtgtcgtg cttgacgcca acggagagtc tatcatcggg
    62941 gcgaacgtag tggtgaaagg taccaataat gggacaatca cggatctaga tggtaaattc
    63001 tcgatcgaat tatcggatgg tgaaaccctg caagtatctt ttatcggcta taacagcaag
    63061 gacgttatgg ttggcgcagg agagaatcat atcaaggtac agctacggga agacacgcag
    63121 aagctcgatg aagtggtagt agtcgggtac ggaacacaga tcaagagggc ggtaaccggc
    63181 tccgtgcaat ccatcaagtc ggaagagatg gcggatatgc ccgtagcaca gatctcgcaa
    63241 aagatgcaag gcaagttcgc cggtgtccaa atcaatcaag tatccggtaa acccggacaa
    63301 ggaatgacca tgcgaatcag gggacaagcg tcactgtccg gaggaaccac gcccctttat
    63361 gtagtggatg gaatgcctat cgtgggcgat atcagcacga tcaatccaga cgagatagaa
    63421 agtatcagtg tgctaaaaga cgcttctgcc acatcacttt acggttcccg ggctgccaat
    63481 ggagtcgtat tgatacagac aaagactgcc caatcaggga aaaaactaag cgtcgacgta
    63541 tatggaggca tacaatacgt acccgagaaa gggaggccgg atatgatgga tgcctccgaa
    63601 tacgcacggt tcaggaaaga gatcgctgaa gagaacggat tggcggtcga tcccgcttac
    63661 cagcatcccg aagcgctggg taaaggcacg gattggtatg acgtattatt ccgtcccgcc
    63721 gctatccaga attacagttt gtcgtacagc aacggagacg ggaagtttaa atcatccacc
    63781 gtagccagct atttcaacca agacggagtg ttgacaaact ctaattacca acggttctcc
    63841 gcacgagcca atacggaata cgtattctcg aagatcgtca aggtaggcgt gaacctagcg
    63901 cctagcttct ccatcaataa tagcccgcaa tcggacggta actggacgga agataaaggt
    63961 tccatcctgc aaggagctat gttgacaaca cctctcgcac cctataagaa tgaggatggc
    64021 agtattccgc ttgtggccag tgggccggga ttgttcgata acccgaactg gtataatgtg
    64081 gttcgcctca acaagaacaa gacccagaac acccatctga tcgcaaacgc cttcttggag
    64141 gtagagccgg tcaaagattt aaaagtaaag accagcatca acgcagactt gacacagaat
    64201 aaatggaact cgttcaagcc ctccacctcc ggagagatct ataaggctcc ctatcagatc
    64261 cccgaggcga aggaatccaa taatctattc tacacttggc tgtgggagaa taccgccacc
    64321 tacagcaagc agataaaaga tcattccttt gatctcctgt tcggcatatc cgcacaaaaa
    64381 taccatagcg aatatacgat ggtgaccgga acgaactttc ccgacgataa aatatcgaca
    64441 ttcaatgccg cccctaccat cacggcggat ggaaacataa acgaatggtc ccttttatcc
    64501 tatatcggcc gtataaacta taattacaaa ggaaagtacc ttttaagcgc agcgatgcgt
    64561 agggatggtt cctcccgttt cggtaagaac aatcgttggg gtaattttcc atccgtatcg
    64621 gcgggctgga tactctcgga cgaggagttc atgaaaccat tggagaaaac gatctctttc
    64681 ctcaaggccc gtatcagtta cggtatcgtg ggaaacgacc agatcggtaa ctatacgcat
    64741 ttggcgacga tcaccaccac gaacagcaac ttcaataacg ccttggccag cggcagaagc
    64801 atctcgggaa tgggaaaccc gaatctgggc tgggaaagga ataagcaagt cgatgtcggt
    64861 ctggatgtcg gtttcttcaa taatcgctta tccatcatgt acgattacta tagcaagcga
    64921 acggacgccc tgctgttctc gctagaggta ccgatctctt ccggcttcta caacatccaa
    64981 tcgaacgcag gcaaactgaa gttctgggga catgaattaa gcgtatcctc caagaacctg
    65041 acaggcaaat tacaatggac taccgacctg aacgtatctt acaatgacaa taaatgcttg
    65101 caactgggtg tagatgacgc cccgatcatc ggtaacaaca tcacgcaagt cggggaacgg
    65161 atcggacagt tttacggctt agtatgggaa ggggtctaca agaacaagga agaattcgac
    65221 aaatacccga agcacgcaca agccgatgtc ggaaccattc gcttcaagga tgtgaacggg
    65281 gatggcaaag ttactcaagg ggatgaccgc gatatcatcg gcaatccggt ccctttatgg
    65341 atagtaggca tgacaaactc gttcacctac aagaatttcg atttgtcaat tgtcgtatcc
    65401 ggcggttttg gttttgagtt agccaatatg gtagatcagt tcgctggaaa tctggatggt
    65461 gtgttcaacg tgtataaagc ggtagacaat cgctggaaat caccggagaa tccgggtaac
    65521 ggccgttatg gaacgaccaa gatgggtacc acggcaccag aacgtgactg gttcagttcc
    65581 cgtttccttt ataacggaaa ctacttgacg atcaagaata tcaccttagg ctaccaagtt
    65641 ccgttaagaa accgggatat cattaaaggt ttgcgagctt acgtcagttt ccagaacgta
    65701 tatacgttca ctagctacat cggcgctaat ccggaggtga atatcagcaa tacgggaacg
    65761 acggcgaata gcttgcaaca aggattcgat tataccacct atcccgttcc acggaccatt
    65821 acgttgggtt taaatgttaa cttctaacta tctaattata cgaaatatat gaaaacgata
    65881 ttcaatatag ccataagcat cgctttagga tgtagttgtg cctcctgtag tgatttcttg
    65941 aatcttacgc cgtatagcga gatcaccgcc gagaacttct accagaacga ggaggatttc
    66001 aggcaagccg taaatggagc ttacgaacct ttacggaaca tgtacaacac ggaagagtgg
    66061 aatctgggag aggccaaatc ggataatacg acgtatatca tccatatcgc caaatcatcc
    66121 ttagacggag aagatccgga tcagttcctt gagacatcca ccaatggtaa tgtcggtacg
    66181 aagtataata actgctacgt aatcatcgga cgatgtaacc ggattatctc agaaatagac
    66241 caagcggatt ttgacgcaga agcaaaaagc aacctcaaag gacaagcttt gttccttcgg
    66301 gcattctgct atttcaacct agtacaatac tttggcggcg tacctctgca tacgacaccc
    66361 tctaccgtgt atgaggaggc atttaaaccc cgtgcgagcg tagacgaagt atatgagcaa
    66421 atcatgaaag acgcacaaga agccagtgat ctcctacctg taaaatcaag gcaagaggta
    66481 ggaagagttt ccaaaggctc cgcacagacc ttattgggaa acgtatacat ggtactaaaa
    66541 cgatgggcgg aagcagaaca aacgctgaaa gaggtggtat cctcaggcga gtatgagtta
    66601 ttagcggatt acggctccat ctattccatc tcgaacaaga accataagga atctatcttc
    66661 gagatccaat acatgcaaga cgcctcatta ggacaacaaa gtgatttcat atacagattc
    66721 ttgccctata tgacgaatcc gtctgccatc acgggaacaa cccctaatcc ttgtccttcc
    66781 aacgtagacc atggtgggtt taacacccct acgatcgatc taatcaacgc atacgaaaag
    66841 ggagacaaac ggttggacgc atccatcggt atggtggaag gtaagctcac cgatagctac
    66901 gccctcgacg ctaccggcgt gaaaagtata gttgactatg agccagctcc gggaataacc
    66961 gcttatcctt ttatcaaaaa atattttcat gagcatataa agccctatta cacggatgac
    67021 aactggccgg tctacaggta cgcggaggta ttgctctttc tggcggaagc tatcaacgag
    67081 cagaataggc cggacgaggc tatccattat ctgaatgaca ccttcgggca agcaagtatc
    67141 cggggaaggg cgggattagc tcctgtcaaa tcccagaatg tagatgcgtt gagagaggct
    67201 atctaccaag agagacggat cgagctggca ttcgagaaca aacgctggac agaccttctg
    67261 agaacgggac gagccgtgga agtcatgaca cgacatggac aaaagataaa ggcaaatccc
    67321 gaatcttatt attggcccga cggtgttcaa cccgtggcga acgcttatct gttcaaccca
    67381 gataaatgct tgttgcccat acctctgcga gaaatcgact tgaacagcga gcttaaacaa
    67441 aatcccggat attaacgaag ttattcttat attcgcatca tgaaaagagc acatatgaaa
    67501 atcctgctaa gtttactatg ctgtgtcggt gtattcaccc tatcagcaca aagtcgttat
    67561 ttcaaagaaa gcgcttcatg gcttcaaaag agtgaggcct gcaagccagt gttaacctat
    67621 acggaacata agccggtcaa acgggtcact tccatcaaag atgcgtcagc ctaccaaggt
    67681 tggcgcatgc gggacgaagg aagcacggat ctgttattca atgagtccct gaagaaacat
    67741 ccatcggtta tagttgactt cggtgagcat ctgacggggt atttggattt ctcgctcaag
    67801 ctccttagcc aacaggtttc ggacgctccg gtacgtatca aattcacgtt cgccgaagtt
    67861 ccctcggaat tgaacacgcc tttcgaccct tatccgggcg gtctgtcaag ggcttggcta
    67921 caagatgagg tgatgacgtt aatgaccgta cccatcgagg cctccatccc cagaagggtg
    67981 tcttttcggt atctcaagat agagttgcta ggcgcttcca gtttcgattt cgccttcgac
    68041 aagctaacgt tccgtgcgca gacatcggct aagacggctc cattgccact ggcttccacg
    68101 accgatccct tgatccgtaa aatcaatgag gtaggattgc ttacattaaa agaatgtatg
    68161 cagaccgtct atgaggatgg cccgaaacgg gatcgccggt tatggatcgg agacttgtat
    68221 ctggaggcgc tagcgaacgc atggtcgtat aaaaaccacg acttgacgaa acgttgcctc
    68281 tatttattag cggctctagc caatgatgaa ggactgctgc acgccaccgt attggagaca
    68341 ccgacccctc atccgcaaaa cggtacgcat tgcttggact attccctgct gtataacgta
    68401 gcgttgctgg aatacctgaa agagaccgga gacaaggagg tcgccttgga cttatggccg
    68461 gtagtggtcc gccaaataga gatggccttg cgtcaatact cggacgattg gatctacgat
    68521 atgcaaaaga agccgattta ttggttggta ttcgactgga aagataatta tgatcgccaa
    68581 gcatccatgc agggacttac ggcattctca ttagagaaaa gctatgagct ggctaaaatg
    68641 ctgggaaaag agaaggaggc tggagactgg cctcgtatcg ccggccagat aaagaaagcc
    68701 gcccggaaaa cattctatga ccaaaagaac ggggtgatcg taagcggccc taaccgtcag
    68761 gtgtcttacc tatcacaagt gtggatgatc ctatcggaga cgcttaccgc caaggaagga
    68821 gcaaaagcga tggccaccgt cctatcgatg cccgacgcat gctatccggg atgtccgtac
    68881 gcttatcatt atgtaatgga agccttgttg aaatgtggaa tgcggcaaga ggcccgttcg
    68941 ctcttaacca gttattgggg cggcatggtg aataaaggag ccgatacatt ctgggaggta
    69001 tatgatccga acaatgacga attatcacct tacggatttt tcccgatcaa tagttattgc
    69061 cacgcatgga gttgcacgcc ggtttatttc atcaacaaat acccggagat attccaaaga
    69121 tagaagataa taagagaaac gccaatatcg ctcgaaatgg aacgtattgg cgttttcttt
    69181 ttcttattcc tccacaggtt ccccgaacag ggttgccgag gaagccttat ggatcttgac
    69241 ttttatgaat tgacctacat gatagttctt cttgtcaaag ataaccacct tattttggct
    69301 ggttcgtccg aacaattgct cacgggaacg tttcgagaat ccttctatca gaacctcgaa
    69361 agtcttgcct atatcccgca agttactttc ctcggacaac ttattttgca aatcgatcat
    69421 accttgcaaa cgacgtacct tctcttcttc cggtacatta tcctccaaat ggctagcggc
    69481 atatgtaccc ggacgttcgg aatatttaaa taagaaagca ctatcatatc ccacttcacg
    69541 catcaaggat aaagtctctt gataatcctc ctcggtctcg gaatggaaac cgcagaataa
    69601 atcagtcgag atagcgcaat ccggtacgat acgacggatc gccgctatac ggtccagata
    69661 ccattcacgg gtatatttac gattcatgac cttcaagatg cgactgctgc cggattgggc
    69721 aggcagatgg ataaacttac agatattgtc gttcgcggca atcacacgca aggtatcatc
    69781 gctcatgtcc ttcggatggg aggtcgtaaa acgaattcgc atatcgggaa cctctttcgc
    69841 cacacgatcc aacaagatcg ggaaggttat ggtctcacct tctttctcga aagaatagga
    69901 gtttacattt tgtcccaaca acgtaacttc cttaaagcct ttctcgtgca tatcccgtat
    69961 ctcattcaag atactctcga tatcccggct acgctcgcgt cctcttgtat aaggtacgat
    70021 gcaatacgta caaaaattat tacaaccgcg cataatagac acgaaaccgg agatatgtac
    70081 gcccggtaac ttcaaaggaa taacatcctt ataggtctct tgggtagaaa gctccacgtt
    70141 gatcgctttc tctccgtgct ctaccgctcc caccaagttc ggcaagtcca gataagaatc
    70201 cggtcctacc accaagtcgg catgatgcac atggatcaga tcttccttca ctcgttcggc
    70261 catacatccc aatacaccga caattaagga cttctttttc cgttttaaag actggaaata
    70321 ctgtagccgc ccatagattt tctgttcggc gttgtcgcgt acggagcaag tattcacgaa
    70381 gatggcatcc gcctcctcga tattctccgt catactatag ccatccatct tcatgataga
    70441 agctacaact tcgctgtccg ccacattcat ctgacagccg taggtctcga taaacaactt
    70501 tcgttcatcg ctttgggtag cggattttaa gtccacaccg ttttcttgat ttaccatact
    70561 atatgttaat ataatttaaa taagcaagat tcttaaaaat aattacgcaa acgcttgcat
    70621 agttcgaatc ccaccgttat atttgcattc gaaaaacgta aattttttca tagttaaggt
    70681 tttggttaaa tcgaataagg gtggctgtga agttaccctt atttactttt atacctatct
    70741 gatgttttat atactcccat cttttcactt ctcaattatt cttcttacat ttggaggtgc
    70801 aaaaataatc aaagtttatg gataacgtag gagattggtt atatattgtt ttcctgatta
    70861 tcgccgccgt cagtggctta ttcagttcga aagacaaaaa gaagaagagt cgccccgata
    70921 tattggggca acccgacagg gaaattgtgc ctaatgacca gcctacagaa ggaaaaggct
    70981 tctgggagat attggaggat atgcaaaagg aaacgcaaaa acctaagccc gctccccgac
    71041 aaaagcaggt aaagccaaag gttgagaaac cgcaagtcgt aacctcatcg cctgcctcat
    71101 ctccattcct ttccgccgag aagaatatcc cgaatcatat cgcgacccag ccatccgtaa
    71161 ggatgagtgc tatcgaggaa gaaccggggc ttatgccaga agataccttc agagacatcg
    71221 aggaattgaa gaaagcgatc atttgtgcgg agattctaaa ccggaagtat taatttacgc
    71281 cacacttata ttcgattcag cgtaatttta tgtaagtttg cgcccgaaat attgaacagt
    71341 aagtatttac ctaaaaacat aaaaactaat tatcatggca ttaaaattta ttacagctga
    71401 agaagccgca tcttatgtgc atcataatga caatgtcggt ttcagtggtt ttacacccgc
    71461 aggatgcccg aaagtcgttc ccggagctat cgcccggaag gcagcggaag aacacgctaa
    71521 aggtaaccct tttcaaatcg gtatgtttac cggcgcttct accggtgata agctagacgg
    71581 agagttggct cgcgctaacg ccatcaaatt ccgtacaccg taccaatcta acaaagactt
    71641 acgtgccgca ttaaacgctc atcaggcaca atatttcgat ttgcacttgt ctgaattggc
    71701 acaaagcttg cgttacggat tcttgggtaa gattgatgtc gcgatcgtag aggctgccga
    71761 tgttactgag gatggtgaga tcgttccgac ttcaggtgtt ggtatcttac ctactatctg
    71821 tcgtatggca gaccgtatca tcgttgagtt gaactgccgt cacccgaaag aaatccgcgg
    71881 tatgcatgat atttacgagc cggctgatcc tcctttacgc cgtgagatcc ctatctacac
    71941 tccttctgac aggatcggta acgattgtgt aaaagtagac ccggctaaga tcgttggtgt
    72001 ggtaagaacc gatgagccga atgaaggtgg aaaattctct ccgctggatg atgttacgat
    72061 ggcgatcggt aaaaacgtag cggacttctt ggttagcgag atcaaggccg gccgtcttcc
    72121 gaaagaattc gttccattgc agagtggtgt aggtaacgtg gctaacgcag tcttgggctg
    72181 catgggagct aatgagtcta tccccgcatt caatgtatat actgaggtta ttcaagatgc
    72241 ggttatcgaa ttgatgaaac agggtcgcgt taaattcgcc agcggttgct ctttgtccgt
    72301 aagtaacgag gtaatccgtg agatctacgc aaatctcgat ttcttcaagg ataagatctt
    72361 gcttcgtccg caagagatct ctaacaatcc ggaggttgcc cgccgtttag gcttgatcgc
    72421 tatcaatacg gctttggagg ctgatatctt cggtaatatc aactctacac acgtatccgg
    72481 tactcgtatg atgaatggta tcggtggttc cggcgacttt acccgttcgg ctatgttatc
    72541 gatcttcacg actccgtcta cagcgaagga gggtaagatc agcgcgttcg taccgatggt
    72601 atctcacttg gatcatagcg agcactccgt gaagatcatt atcacggaat atggtgtagc
    72661 ggacttacgc ggtaaatctc cgatccaacg cgctcgttgc atcatcgaca attgtgttca
    72721 tccggattac aaaccgttat tggaagaata cctcgctatg ggtatcaagg gacatacgcc
    72781 tcaaaacctg aaatgctgtt tcgctttcca tgaggaacta gcggccagcg gcgatatgca
    72841 caatgtggat tggagcaagt ataataagta atacaaacat attacaggca taattcatag
    72901 ggcatgggtt caaccgaact catgccctat tctcatagca gacaatgcgt aatacatttg
    72961 taataatttt gaaacaattc tttcaagcgg gtttaatctc tccttaatat agaggctctt
    73021 tctttgcagc agaataaata ggcaaagatt gtgagaaagt ttatagaaaa attagtggaa
    73081 ggaggattct tgatcagtgg aagcgtcagt agctttacga tcttgttgat cattgtcttc
    73141 ttatttaaag aggccgcagg tctttttaac agcccggagg tagaggaagg atatatattg
    73201 gctgtgaatc aggaaaatcc agtcgaacat ttgtctcccg agcaaatcat ggatgtcttc
    73261 gatgccaata tcaccaattg ggaagattta aacggagaaa atcaagatat acttgtcttc
    73321 cgtttctcgg acctaaccaa ctattatacg gaagaagagc taggtgaaga atttcaatat
    73381 gttcccgaga aaatcaatga acttatccat aaagagccgg ggattatcgc attctttccg
    73441 gaacaataca agtcggagaa ctttacggga aaaatcatat cgggagccac gatcaaacct
    73501 tcggagttct ttggagggac gaaatggtat cctacctccg ctcccgctcc gatctttggc
    73561 ttgatccctc tattactagg cacactttta gtaagtatag gcgcgatcgc cttatccctc
    73621 cccttcggag tagcggtagc gatctatatg gcagagattg ccaatacaaa aacccgtaat
    73681 ttgctaaagc ctattatcga gttattggca ggtattccct cagtcgttta tggtttcttc
    73741 ggattggtgg tgatcgttcc ccttatccaa aagaccttag accttccggt aggcgagacc
    73801 gctttcgccg gaagcgtggt tttagcgatc atggcgttgc cgaccatcat cacggtagcg
    73861 gaagatgcca tgcgaactac cccacgagcc atgaaagagg ccagcttggc attgggagcc
    73921 acgcaatggc aaaccatcta caaagtaata atcccctact ccatatccgg tatcacgtcc
    73981 gctgtcgtat taggtatagg acgtgcgatc ggtgagacga tggccgtatt gatggtaacc
    74041 ggaaacgccg ccgttatccc tacctcgttc ttcgaaccgg tacggacaat tcctgccacg
    74101 atagcagcgg aattaggtga ggctcccgca ggtggagcgc attaccaagc cttgtttatg
    74161 ctgggagccg tgttgttcct catcaccttg gggttgagca tcgccgtaga atatatttca
    74221 tccaaacgta aaatttaatt aaagatatgg cacctattca acatttaggg aatatagaca
    74281 agaggaaacg gacctctcaa caggttgctt tcggtttctt ttctttcctg agttatttgg
    74341 tcgtagtgat cttattcgta atactgggat tcattatctt aaagggagcg agcgtgatca
    74401 gttgggattt cctgacacaa gcaccccaag agggcatgac ctccgggggg atttttccgg
    74461 ctatcgtagg tacactctat ttagtgatcg gaagtagctt gattagtttt cccatcggca
    74521 tcatgagtgg tatctatatg aacgagtacg ccacaaacgg gaaactcatc cgtttcatcc
    74581 gtatcatgac gaataaccta agcggtgtcc catccgttgt tttcgggtta tttggtatgt
    74641 ctctattcgt aagtaccttg ggatggggag actctattat agcgggttcg tttaccttgg
    74701 cgctgatgtc cttgccactt atcatccgca cgacggaaga ggctttgaaa agtatcgatg
    74761 attctttccg tcacggtagc ctagcgttag gggctacgaa gttgcagacc atccgcaggg
    74821 tcgtgctacc gatggcgttc cccaatatta ttacgggatt gattctttcg atcgggcgtg
    74881 tgtccggaga gaccgctcct atccttttta cggtggccgc ttatttcttg ccgcaattgc
    74941 cgaaaagtat tttcgaccaa tgtatggcat taccttacca cttatatgtt atctctacaa
    75001 gcggtacaga tatcgaggct tcccggggga tggcttatgg cacggcgctc gtgctgatcg
    75061 tcatcgtatt attagtaaac cttttagcga acgctttacg tagttatttc gccaagaagg
    75121 taaaaatgaa ttaaaaaaat aagacaatta tgataaagat tgatgctaaa aacgtagact
    75181 tttattatgg ggatttccat gcattgaaga acatttccat ggagatagag ccgaatacgt
    75241 ccaccgcttt cataggaccg tccggttgcg gaaagtctac tttcctccgc ctgttcaacc
    75301 gcatgaatga tttgattccg gacactcgca tggaaggtca gatcctgatt gatggaaggg
    75361 atatttatac gaaaagcgag agagtggatc gcttacgtaa aaacgtgggg atggttttcc
    75421 agaaaccgaa tccttttcct aagacgattt atgagaatgt cgcttatggc ctgcgggtaa
    75481 acggtgtcaa cgatgagaat tatattgagg agacggtggt caagacttta aagcaggtcg
    75541 tcctttggga cgaggtaaag gataaactga aagaatcggc attcgctctt tccggcggac
    75601 agcaacaacg tttatgtatc gcccgtgcct tggcgatctc gccctccatc ctattaatgg
    75661 atgagccgac ttccgcattg gacccgattt caaccagcaa gatcgaggat ttgatacatg
    75721 agctgaaaaa tgattatacg atcgtaatcg ttacccataa tatgcaacaa gcggctcgtg
    75781 ttagcgacaa gaccggatat ttctatttag gggaattgat tgaatatgat aatacccgga
    75841 agattttcac caatccggag aaagagtcta cacagaatta cattaccgga cggtttgggt
    75901 aattgaaaat taaaaattga aaattagaag agtatgaagg ttatagagca ggagattcat
    75961 tctttaaaaa atagtatcag cgagatgtgg gcattggttc accagcaatt atacaacgca
    76021 ggggaggcta tgcttaccgg agataaggaa ctcgcttata aggtaatcag ccgggaacgc
    76081 cgggtaaacg ctttcgagct aaagatcgac agtgattgcg aggatatcat cgctttatat
    76141 gcgccggtag cgatcgacct acgtttcgta ttggcgatgt ataagattaa tacaaaccta
    76201 gagcgtctgg gagatttcgc cgaaagcatc gcccgtttcg ccggaaacct tcccgagggg
    76261 gaaccgattg acccgcaact ggtcaaggaa acccgggtag aagaaatgct gtcggagtta
    76321 ttaagcatga tctcactcac caaagaggct tttgagaaag aaagctcaga gatcgcttcc
    76381 cgtatcttct tgaaggataa tttgatcgat gagatcaatc ataattctac cgctattatc
    76441 gccaaatata tagaggagca taaaggtagt gcgttggcag ggttatatat ggccggtgtt
    76501 atccggaaaa tggaacgttt cggagatcat tgtacgaata tagcggaaga gctcattttc
    76561 tatctggacg ctaaagtcat gaagcatatg ggcaaaaccg agcaataatt cgtatcttcg
    76621 cggccacttt aacaatcaac atcagtaaat gaaacgactc acagtggctt ggctgtcggc
    76681 cttcttattg agcggttccg cattaacgtc ttacgctcag acaaattctc ctatcccgga
    76741 gcgggattct tcttcggtat ctctttttga atacgcgact aagattccga aacgcaacaa
    76801 ggttttcaat ctggacttgg agatgcacgc aggattcaac gcagactttt tctcggggaa
    76861 gctggatgaa gccgcctttc gtttcaggga tgtcaaaatt gatgttaccg gagaggtgaa
    76921 cgatcggtta ttctattggt atcgccaaac gctgaatggc ggttatgagg gacaagcctt
    76981 ggagaatttg aatgagtcga tcgaatatgc gtatatcggc tataaactga atgagcgttt
    77041 taccttaacc gccggaaaac aagatgtgtt ctacggtggt tttgagtacg acgagaatcc
    77101 tttgcttatt tatgagtata gcgatatgaa tgaatactcc ctttgctacc ttacgggaat
    77161 cgggctgggg tatcagccga atgagtcgca agagatccgc ttacaggtga cgaacagtcg
    77221 tatgggatcg atggaagatg agtatggacg tctgccggaa ggatttaaga aaccgagagt
    77281 tcccttgttt tacacattga actggaacgg taactttctg gatgagttga ttcatttacg
    77341 gtactccgta tccgctgcgg aacaagccca agggaaatat atgtatagcg tctttaccgg
    77401 tcaaagtata gaggccggac cggtctatgc ttatttcgat gtcatgtatt cacgaggaaa
    77461 attagaccca ttaggattat tgaccgaatt gacccagccc gaagtctccg gagaggagga
    77521 accggaacca ccggttcgta tgcaaaacat cgattatctt tcgctggtgg gggaaataca
    77581 gtatcgtttc catcccaaat ggcaactatt cgcgaaagga atgtatgaaa gcgcatcgat
    77641 ctataaagcc tacgatgctt acgagaaagg taaataccgt acggcatggg ggtatcaagg
    77701 agggcttgag ttctatccga tggccgatga taatctacat atcttcttga ccgccatagg
    77761 taaaaaatat aacctatccg aacgagcgaa ggcgctcgat gcctctctgg acgacaccgc
    77821 acgcctttcg atcggtttca tttatagatt accactatat tgaataatgt gccaatgtgg
    77881 gtaatgtgcc aatatgccaa ttaaatggat atattcgcag ggcacattgg catattggca
    77941 tattattcac attattaata tcaattcgtc tccttgttgc aaatccaccg ttagcattcc
    78001 atcgattacg ggtaaagata ctggtttctg atttttcttg agacttaggt tcgctgaatt
    78061 tgccggaagc ttgatccgga aaatacccgg aacgatcgct ttcaatcgag cttccgtcag
    78121 cagaccttcc gtccatttag ccgacacctc tccgccattc cggactttca aaccgctaaa
    78181 gcttccgttt ttccaagcgg aaggcaaagc cggcaaaaac tcgatcaatc cggtttgact
    78241 ctgtatcagc atctccgcga tacccgccgt gcctccaaaa ttaccatcga tttggaaagg
    78301 aggatgggca caaaacaaat taggataaga acctcctccc ttcacctcct tcgtatgctc
    78361 atctacgcaa ggacgtaaca aatcacccaa caatttataa gcatgatcgc catcctgtaa
    78421 acgagcccag aaattaatct tccaagccat cgaccagccc gtgctttgat caccacggac
    78481 ctccaaggat ttacgagccg cctcagccaa ctctggcgta tgctctatcg atatctcatt
    78541 cccgggataa agcccatata aatgagagac atgacgatgg gtaggctcta cctcctcata
    78601 cggctcgagc cattccataa tacggccgtc tttaccgatc gtcgttggca tcaagcgatc
    78661 tcgtttcgcc gccaactcag cagcgaacgc gctatccacg cctaaaatcc cggcggcctc
    78721 aatggtattc gtaaataatt cccgcacgat ctgattatcc attgtcgatc cggcacaaat
    78781 actcacgaca cttccgtttg gcattttata agcgttctcc ggagaggtcg taggtgccgt
    78841 caccagatat ttagtccggg gatcttgcac caacatatcc acaaagaata gggcagcccc
    78901 tttcatcgtc ggataaacat ccctcaaata cgccttatct aatgtatact gataatgcgt
    78961 atacaaatgc tcgcatagcc atgcggcgga tgtattcgtc gctccccacg atggatgttc
    79021 gcccggggcg gtaaactccc aaacattacc taaaatatgg gtaacccatc cccgtgcgtt
    79081 ataaaaagcc ttggccgtgc gttcgccgct agggacttgc agtttcgtcc attcgatcag
    79141 cggaaggtgc aactcggaga ggttcgtgac ctccgcaggc caatgattca tctgtaaatt
    79201 aatatttagg tgataatccc cgttccaagg cgtatgaatc gtattacacc acaagccttg
    79261 caaattcggg ggcagtaatc cctgccgggt cgaggaaatc aataaatatc gaccgaactg
    79321 gaaatataaa gccgccaatc ccggatcgtt cttatcttga gcgaaagcgg ccaaacgctc
    79381 attgatcgga agatgatccc tttcgcctct tcccaaatcc agagaaaccc gatcgaacag
    79441 ggagcgataa gcaagtgtat gttcccggcg caaggtggag aaatccttag attccgcttg
    79501 cgataagtat ttttccaagg attgtccggc gccgtcttta tcgaaataat ccgtacctaa
    79561 acttaccaag ataatcgctt ccgaggcact tcgcaccgac agacagctat ctgtcgtagc
    79621 caaatctcct cccttcggca agacgatacg gacacgagag gcgaaacgca tccctttcat
    79681 ctccaacgta tccaccccgt ccggcagttg tccccgcatc agcaagtcct ttccgtccaa
    79741 agagatcgtc gcatgttccg gacgattcat acccaatgag aaattcaaag cccgatccgt
    79801 atccgctacc aaatgaatca ctcccagatc accggaaaaa gaggtaaaca tttcccgttg
    79861 ataattcaca ttcccccttt taaaagagac ggaagcgata gcctcgctta ggttcaaccg
    79921 cctgcgatac tcagcgatag aatccgattc attcggatac gtatatttca gcactagatt
    79981 tccgaataat tggtaactcc catacggagc gttcgcaccg tcacccagat tacttccggt
    80041 ccctttgcag acgaaagttt tatacatcaa atcctgtgcc tcgtcattcc gtccctcaaa
    80101 taaaaggcga cgaatattcg ccaaagaata atacgcataa ggattgtccg tatcttgctt
    80161 acttccggac cacagggaga tctcattcag gacaacattc tcccgctcaa taccaccatc
    80221 cggcatcata ccgatacggc cgtttcccaa aggcaaagtt tcttcccata tctgcgctgg
    80281 ttgatcaaaa taatatgaga cctccttccc ggtctgcata tccggcaaat tacaaccgaa
    80341 aaggaacgat aacaaaatca aataaagtcc tttcatattc atacgattat tccttgttat
    80401 tgtttttcca tcaaaagccg aagaggcgat ccactgcaac ccgggttaca gtatcaccct
    80461 aaaagctttg catatcacat agtcgtttat aatagccatc caaagccaac aactcctcgt
    80521 gtttgccccg ttctacgatc tcaccctcat gcatcacaca gatctcatct gcgttacgga
    80581 tcgtagagag acggtgggcg atcactacgg tcgtacggtt cttcatcaag ttctccaacg
    80641 cttcttgtac caaacgttcg gattccgtat ccaaggcgga tgtggcctca tccaagatca
    80701 agatcggggg attcttcaag atcgcacggg cgatactgat tcgctggcgt tgtccaccag
    80761 acagttttcc acctcggtca cctatattgg tatcgtaacc tttctcactc gctatgataa
    80821 aatcgtgagc gttagcgatg cgggcggctt cctccacctg ttccatcgta gctccttcca
    80881 ctccaaaagc gatattgttg aagaaggtat cgttaaacaa gatagcctct tgattgacat
    80941 ttcccatcaa tcccctaaga tcgaaaaggg tggcctcacg gatatccgta tcatcaatac
    81001 gaatattccc tttattcaca tcataaaagc gaggcaatag atccaccaag gtacttttgc
    81061 ccgaaccgga ttgaccgacc aaagccacgg ttgttccttt ccggatatcc agattgattc
    81121 ctttcaagac ccaagcttcc tgatatttaa accagacatc tttataactg attttctctt
    81181 tcaaggcgat cttcttcgga tgttccggat catggatatc cgtctccgcc ttcaagatct
    81241 tatcgacacg ttccatggag gccagacctt tctggatcgc ataaaccgac ttacttagat
    81301 ctttcgcagg attgataatg ctatagaaaa taaccagata ataaataaac gtaggagcgt
    81361 cgatcgggct attcgcgctc aagatcagcg tacctccata ccaaagtacg atagcgatcg
    81421 taacggttcc caaaaactcg ctcatcgggt gcgccatttg ttggcggcga tagatacggt
    81481 ttgtcaaccg acggaaagta tcattgcttc gctcgaaacg gtcttgtatc ttcttctcgg
    81541 cgttaaaagc cttgataata cgaagtccgc ctaatgtctc ctcgatctgg ctcatcagaa
    81601 atccccattg ttgctgtcct tccaaggact tccgtttcaa cttcttaccg acttgtccca
    81661 ttacgtaacc cgccaacggc aacaggatca agacgaatac ggtaagttgc caactgatag
    81721 cgatcatacc caccagatag atcacgatca ggatcgggtt cttgaataac atgtccaatg
    81781 aactcattat ggatgtctca atctcgttca cgtctccgga tacacgggcg ataatatccc
    81841 cttttcgctc ctcggagaaa aagctcaacg gcaactgcgt aatcttcttg ttaatctgat
    81901 tacggatatc acgaacgact ccggttcgaa tcgggatcat cgtataaaaa gccagataca
    81961 tggtcgccac tttcaagaaa gtcgccacga tcaggaagat tcccaacata atcaaggcga
    82021 acgaaccgcc gtgtacctct atcagatcgg atacatacca aaaaaagtta tttttgatca
    82081 actccggcaa ggctttccac gactcccagc ttcccgcgtt aaaattccaa tccataaagg
    82141 tgtaattccc ctcatccatc ttaaacaaga tctgaaggat cgggataatc aaggcgaaag
    82201 aaaacaggtt caagatagcg gaaagtacat tgaacacgat gttcagaacc atatactttt
    82261 tgtaaggggg aacgaaacgc tttaaaatac gtatgaaatc tctcataaat tgatctgtta
    82321 cattgaagtg gcaaagatac aaaaagtaca gctatatcaa cccctattat ataaagagaa
    82381 aagacaaata ccggacggta agcaactatt ttgcgtatat tcgcatctat atatagtgca
    82441 aacaaataaa aacgatcaga tcatggaaaa catcaacttg caactattaa gaaagatcaa
    82501 ctgtctatta accggattat tggccatcat aggattctct tgcggtgaga atggagagat
    82561 accttgcgaa tatggtagtc cccatgccaa tttccaaata aaagggaaag taacagacat
    82621 gaaaggagag ccaatccccg acctacaagt ccgcatcaac ccgagcggag agtctcatcc
    82681 gcagggatgg ttacataccg ataccctcca gacagataca aacggagatt tcatttttag
    82741 caaaaccgat ttccctttca tggaatatcg attaattata gaggatatcg attgggataa
    82801 gaataaggcg atatatgctt ccgatacgat aacggtcacc ttcgacagca atgatttttc
    82861 cggaggagaa ggctggtctc ttggaagcgc ttccaaggaa atccaaatcc aactaaaaga
    82921 atacatcgat acacacacgg aaccttatac cttatatacc ttctacggga gagtaaccga
    82981 tcaagatggt tggcctgttc cgggcgtaac aatctatacc tctccggcct atacgcctaa
    83041 tatagatgaa gatatcacca gttttcctgc cgtcacagat gagaccgggc gctatcagtt
    83101 tacctatgat caagctccgg caactgaaca taccctttac gcacgcctat caccatcctt
    83161 ttctgatcct caatatcctt ggaaaactga ttctattgtt gtaaatttcg gcgaaattga
    83221 attaatagac ggggaaggga tgctgattgg gagaggatcg aaagaggtta actttcagct
    83281 tgtacattcc agcccacaaa aataacacat atggacaaac gcccaaacat caaaaaacgt
    83341 atcgccctag agctttttcg aagtatcaag aagaacaggg ctaaattaca tgaattgcgt
    83401 acactcttt
//
LOCUS       DBMDTB010000004        81113 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_135_length_81113_cov_11.671715, whole genome shotgun sequence.
ACCESSION   DBMDTB010000004 DBMDTB010000000
VERSION     DBMDTB010000004.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 81113)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 81113)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..81113
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_135_length_81113_cov_11.671715"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..225)
                     /locus_tag="ACZPB4_01285"
     CDS             complement(<1..225)
                     /locus_tag="ACZPB4_01285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA/RhaT family transporter"
                     /protein_id="HIR1096893.1"
                     /translation="MNAKAKGYVLGAIAAATYGMNPLFALPLYKAGMNPDSVLFFRYL
                     FAIPVLGIMIKARGRNFKLKPNEIVPLILMG"
     gene            325..627
                     /locus_tag="ACZPB4_01290"
     CDS             325..627
                     /locus_tag="ACZPB4_01290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PAAR domain-containing protein"
                     /protein_id="HIR1096894.1"
                     /translation="MPPAARLTDMHTCPMQTPAWPSPIPHVGGPIVGPGAPTVVIGKL
                     PAAVMGDNCVCVGPPDTIIKGSSTVMICGKPAARMGDTTAHGGQIVLGCPTVIIGG"
     gene            710..1762
                     /gene="trpS"
                     /locus_tag="ACZPB4_01295"
     CDS             710..1762
                     /gene="trpS"
                     /locus_tag="ACZPB4_01295"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HIR1096895.1"
                     /translation="METVVSGIRPTGNLHLGNYFGAVKSFLRMQDEYNCFFFIADWHS
                     LTTHPHPDNIRNSVKTILSEYLACGIDPEKATIYIQSDVPEVVELYLYLNMNAGIGEL
                     MRTASFKDKARQQLHISREGCEGDVEKEIFNEGNKHSVSAGLLTYPTLMAADIIIHKA
                     LKVPVGKDQEQNMEMARRFARRFNSTYGVDFFPEPASFHLGNKSVKVPGLDGSGKMGK
                     SEGNAIYLIDDEKTIKKKVMKAVSDAGPTEPNSVKPEPIANLFTMMEIVSEKETYDFF
                     NEKYNNCEIRYGDMKKQLAEDINKFCAPIRERIFDMAANTEYLDKVARMGAEKARESA
                     SKTLNEVRQIIGFRPY"
     gene            1912..2424
                     /locus_tag="ACZPB4_01300"
     CDS             1912..2424
                     /locus_tag="ACZPB4_01300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma-70 factor"
                     /protein_id="HIR1096896.1"
                     /translation="MAAITTQEFEHHFKSLYKPLCLFALRYTDQVDDAEDIVQQAFAD
                     VWDKNRAGNVIGNLKAYLYQAVRNRSLSFTSQPVNAEATEQLPDVEDTSEEEDILRSE
                     RDARLWDAIDRLPPERKKIFLLSKRDGLKYQEIAEELNLSVKTVENQMSKALKALRET
                     AIRVYMFFFG"
     gene            2513..3322
                     /locus_tag="ACZPB4_01305"
     CDS             2513..3322
                     /locus_tag="ACZPB4_01305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0015288 - porin activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="porin family protein"
                     /protein_id="HIR1096897.1"
                     /translation="MRKLVVFVMLMTCVISAQAQWKVTPEAGMNVTKYKGDAAKVGFK
                     AGAAVSYTFGSGWFSLQSGLYYVRRGKGLSSYSEIYGTSESPYGGREGTSIFLYPVSS
                     DYLNLWGYGYGNGYGFTGFYYDTYGIKDFDVEGIRHRSQKEHREYIQLPILARFDWQV
                     SKDVRLHLAVGPYLAVGLGGKVTYEESDYSLKGKLPYNKEISYNPFNPGQGYAVAPRF
                     DWGATIEAGIEVKRVAFKVGYDLGIDKQYKGYAYNIGLNYHTASFTLGYTF"
     gene            3524..4366
                     /locus_tag="ACZPB4_01310"
     CDS             3524..4366
                     /locus_tag="ACZPB4_01310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecR family protein"
                     /protein_id="HIR1096898.1"
                     /translation="MNNEHGNKLEQRVRFVAKRYREGSLDPDKAWQKFASEHAISRKV
                     SFRRYWIGAAAVVLVLVGLGTWFTVERNAPDWVAITTAPGQMKDVYLPDSTLVALAGD
                     SWIRYDAKRYDKERRAVEMNGKAFFQVTRNEARPFSVKTSQTEVTVLGTSFQIDEKPT
                     VTEVNVVTGKVCFTAGEEKENVILTAGMSAQYSMENKEITVVTEEDVNKLAWRTGQLR
                     FMETPLDKVIEDLSDYYQVKIANQTKNEGARLTATFNNLPLEDVLQVVNQTLDARLVS
                     TSKK"
     gene            4381..7041
                     /locus_tag="ACZPB4_01315"
     CDS             4381..7041
                     /locus_tag="ACZPB4_01315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor domain-containing
                     protein"
                     /protein_id="HIR1096899.1"
                     /translation="MRSIVVWLIGILLLPGWMGHLYAQMPEPTPTVTLDMRQVPLLDI
                     LMELEKQTGLFFSYESSLLKELPEVSLSVRDESLSYCLKRLFSPLPIIYRVTGQYIIL
                     KRKPRQYTISGFVRDSASYESLLGASVLVKSSRGGTMSNNYGFYSLILPPGKVRLRAS
                     YVGFKAMEIEIDLQRDTMIDFPLRSLASLGEVVIRGSRPRYEILSSRTGVIDVPAERV
                     KSMPALLGEADLVKTLQQLPGVAVGTEGMTGLYVRGGGADENLYLLDGNPVYHVNHLL
                     GFFSAFNPDAIKNTRFYKGSFPAEYGGRLSSVVDVRMNDGNRQEYHGNISVGLLSARA
                     NLEGPIVKDRSSFNISVRRTWLDLITGTALAIVNKNSDTKESFGYHFFDINAKVNHSF
                     SERSRAYLSFYMGQDAFRQGSKEKHEDSDDMFLWRWGNLIGSAGWNYVFGQKLFGNLM
                     VGYSRFRSHIRQEAKGYEIEGNRAERQSIKRDSRYKSEMEDLSVRLSVDYSPSMNHRI
                     RMGTDYLYHNFRPENSQQRSWVNDSLVNPVYELLYDYSLIKGHEFSLFAEDEMRVTDR
                     LRVNAGLRYTLFHVENEIYHSFQPRLSARYLLRPDLSAKISYSKMNQYVHLLSNTYVN
                     QPTDIWVPVTEQVPPMSSHQITAGLYYNLKRMYDFSIEGYYKRLNNLIDYKDHWPVET
                     HFSGWEDRVGLGKGKTYGVEFMAQKTNGKTTGWIGYTLSWSDRWFPDGSVNKGRHFPF
                     RFDNRHKVNVVVSRKLSRKVELTGAWVFASGNHISLPEYKYLSPIYQKENGYAGVEYR
                     PMNSGLSARNNYQLSPYHRLDLGVNFYRYKKKGRMGIWNISIYNTYLKPNPFMTEVMV
                     NQDINQRYHVVLQETILFYCMPSVSYTYKF"
     gene            7045..8067
                     /locus_tag="ACZPB4_01320"
     CDS             7045..8067
                     /locus_tag="ACZPB4_01320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009016870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4249 domain-containing protein"
                     /protein_id="HIR1096900.1"
                     /translation="MKRYLPCLFVLGLLMVSCVRDVEIDLEDLPDRIVLNASVCPGKE
                     VCAHLSKTWFIMDSVPDFELSDAKVRVYVNDEFQGLMRNDDLPEDSIHSRGQYVLPGC
                     FVRQGDCLRIEAEADGYEPVSGETRIPGRARIYEVDTLSYRSSAYYAEYLRFSVKIGV
                     ETDSYYRLIVEQILDFRKGDSTRTVTSFRSLGGYSWYYSGFSVDYEDPVFQSFGGSPI
                     TSQMDGRYCMGVFRGEDLVNTNAIKVSVFPVEYSYESDTLSMDVHYDVRLLSISEDYY
                     RYMKIMRGYSITIGDANFGALIEPADTYSNVENGFGIVAGYQEDKLRITMPRDTVPPY
                     WNPWDG"
     gene            8208..10970
                     /locus_tag="ACZPB4_01325"
     CDS             8208..10970
                     /locus_tag="ACZPB4_01325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010182289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor domain-containing
                     protein"
                     /protein_id="HIR1096901.1"
                     /translation="MMTEWMNKWLMAIFCWMIFMPVPDLLAQSAKTKDDPRITLRMKE
                     VSLPEVLSEIERQAGVTFSYESSLLKELPKISFQVKDEALTDCLTRLFESYPIVYKVS
                     GKIVILKRRQRQVTISGFVRDQASSESLIGASVYEVASRKGSATNSYGFFSLTLPPGN
                     IRLHASYIGYESCSFNFTELDRDTILNIELRPNARLEEVVVTASERDRLSVNNTLMGT
                     MGFSQKTIKATPTLFGESDIVKTLQLTPGVASGTEGLAGLYVRGGDQDGNLFLIDGNP
                     VYQINHVGGLFSAFNPEAIRNLDFFKAGFPARYGGRLSSVVDVHTKEGNMKEYHGSAT
                     IGLISGNLSLEGPIIKDRTAFQIALRRSWLDVLSAPAIAIANKVRKDGHKINLRYAFH
                     DLNLKLNHRFSDRSRMFFSLYNGNDVLKGGGTDFSTEEEQVPYTDGTHSSLRWGNLMG
                     TLGWTYVFNNRLFGRVSGVFSRYRSNVRSSKEYNYGVEGEDNYLSSSSETSSSTSILD
                     MGVRSSFDYTPSTSHVIRFGGDFLMHRFRPEYNEVKAAGSGMLEFSNIGKIYTNDLLW
                     AREAAVFGEDDWNVLPSLRLNAGLRFSLFNVERKAYTLLEPRASLRWLLRDDLSFKAS
                     YARMGQYIHLLGNSYINLPTDAWMPVTRKLKPLISDQVSAGFYYNLMRSYSFSVEGYY
                     KWMKNLLDYKDGYSFLPGTAAWEEKMAVGKGRSYGVEFLARKESGRTTGWIGYTLSWS
                     DRRFDEIDNGRRFPARYDNRHKLNIVVSHKLSDKVELTAAWTYTSGNRMTLSLESYEQ
                     AQAGTLNSLDPYGQDNWSGSSGEVVDLYTRRNNYQMPAYHRLDLGLNIYRPKKKGRMG
                     IWNISIYNVYSRMNPFMVYKSDSWERTNNLVPGSSSPYSGNRKPCFKLIGIMPIIPSI
                     SYTYKF"
     gene            10975..12090
                     /locus_tag="ACZPB4_01330"
     CDS             10975..12090
                     /locus_tag="ACZPB4_01330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4249 domain-containing protein"
                     /protein_id="HIR1096902.1"
                     /translation="MKQIKSILINTICIVSLSGLMSCVKEIDLESLRPNPTLVVNCVA
                     ITGESLTVSVSRTWFFTDDHPNVTLDKAEVNLFVNGVFKERMSFQEGDEAFNTKGYFK
                     SDFIPVKGDRIRVEASYPEYGVASAETVMPAPAQVLKAGVTYATVAGSFGSARQNAIY
                     QVTLKDNPAEENYYLLRMEEGIPVFDGIAKEYTGEYKWFSVSPNYATEPVFGQSLTAL
                     DQIFGNDWMYGYDGKVFSDELINGQEYTLHLTDEYYYEPYYGSYPLKVVPDSIGMEDL
                     NEEDFLPIPPKHLRVHLYAISAEYYRYLKVLQDKDTDSVSNLLIDGGLAEPIRVFSNI
                     DGGVGILGSCHVGMFETEIASSSHSNLEAARFEDGID"
     gene            complement(12043..12861)
                     /locus_tag="ACZPB4_01335"
     CDS             complement(12043..12861)
                     /locus_tag="ACZPB4_01335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1096903.1"
                     /translation="MRRGLFIFMAWICVVGIQAQSDFSFILNKEGKIIVLPKNKTYEL
                     NIPKASYKTFTPAGTRDIDIKLREFTPDIPHTSLQERPMDMQISSAAYQPFFNVYTPM
                     LREVSPMALDFNETYMKRLNESFDLIANGVQYTWPGVGGMTIMNGGISWHSGNWSLYG
                     GGFGGRFFSPFNPSPGITAGANVQVEYQPTDWLKLKGWGQYAYYADEYNNPHMLSNPF
                     LYHTQVGGSMEFKITDNFWMGAGVNYEYNPVRRKMEPQFLVYPVFKSGRFKIGM"
     gene            12963..13514
                     /locus_tag="ACZPB4_01340"
     CDS             12963..13514
                     /locus_tag="ACZPB4_01340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HIR1096904.1"
                     /translation="MDEQLLIDGCMRGESWARKELYEQYAPAMMSVCMRYVGDRETAR
                     DLLQDGFVKIFTKIRSYSGSGAFGGWIRRIFVTTALEYLRSSENTRLSVGLDGYDDSL
                     EDINYSVLDRLSADDLLACVAQLPSGYRTVFNLYAIEGYTHSEIAEMLHVQEATSRSQ
                     FIRARNALQKSVQSLIRHENAGR"
     gene            13501..14883
                     /locus_tag="ACZPB4_01345"
     CDS             13501..14883
                     /locus_tag="ACZPB4_01345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0015288 - porin activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="porin family protein"
                     /protein_id="HIR1096905.1"
                     /translation="MRDDKDHNERLDDFSGYMRQRLEEHRLPVDAGCWDEVEARMNRR
                     ARPRGWLWTGGLVVAAVLALVIWLLPSPEKMPLEELSPFQKEISEKAEEMNILSEHPV
                     LPVEPVKKRIAKVLKWEKKAKLSAIVGEKETIREDEKCETIEIIEKDAIAAIVEEPSV
                     KEDASEDSTDIVVKRGDSTVPLPEGERSPRRKASLKKKAKKSKRNKWLLAAAVGSSGY
                     VDSFLNTDMSYGDASSPGDMNNSAGSPDPDKPDKDDDEKESGNTPPQTVSFRNAPVLR
                     SSKVDENFLDNRSFESYPDVSYSLPISFGFTVRKDLSRRIAVESGLMYTYLSTTFKRG
                     GDCPSEVKSSLHYLGIPLNLVVYVWKNQRWNVYLSGGFMMEKGLQAVYSGYIAGNGTT
                     ISKSKKEGIHGMQWSVNASVGAAYRFYGDWSLYFEPRFSHYFDCDQPASIRTDKPLGF
                     GLSAGIRYAF"
     gene            14904..16166
                     /locus_tag="ACZPB4_01350"
     CDS             14904..16166
                     /locus_tag="ACZPB4_01350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LVIVD repeat-containing protein"
                     /protein_id="HIR1096906.1"
                     /translation="MWKLFYWAFAFSLCVLMGCKDDGVRVEVVRYAINEPVFMSISEF
                     RNSVKVTDEVVPITKRGKICFYKGYLYISSPDKGIHIVDNRNPASPRIAGFVELIGNE
                     DLSIKDDKLYADSYVDLVWFDISDPERPELEGRVENAFRYALPTIENGYGFDYNMCYS
                     EEARAKGVVVGWEPKEREETIYHYPSYGGDLMANDAAPGTSTQGVNGSMARFSIYGKY
                     LYTVEQNIMCVFDLSGDKPVLTTNDIWLQRDVETLFNYKDKMFMGTPTGMLIYSLEDP
                     LAPKYRSSVSHVFGCDPVVVEDDLAYVTVHSGNTCGQNTNELMLIDVSDVDQPNLLVT
                     YGMKCPKGLGIDNGTLFLCDEGLKVFNAKDPMTLLANQLVHYAGMEGYDVIPFRNTLM
                     MIADDGLYQYDYSNLQAISQLSKLPMGE"
     gene            16451..17545
                     /locus_tag="ACZPB4_01355"
     CDS             16451..17545
                     /locus_tag="ACZPB4_01355"
                     /inference="COORDINATES: protein motif:HMM:NF019335.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor plug domain-containing
                     protein"
                     /protein_id="HIR1096907.1"
                     /translation="MNLFDNMHGLKGCIRCLTFKNVLLAHFLLAFSVAGSVSAEALPT
                     SYLNGIEQQSRKVAGRVLQRVDNEPVIGANIVVTGTTIGTITDVEGRFSLDNLPANAR
                     TLTVSFVGMTSQTLPIKSEMMILLEDDSETLDEVMVVAYGTAKKSTFTGSASLLKSEK
                     IEARPVTSATSALLGSTPGVQVASASGQPGSDSDIYIRGLGSISATNTPLIILNGMPY
                     DQSISSINPSDIESMSVLKDASSAALYGARGGNGVILITTKTGSKDRMSVNVKINQGF
                     TNRQSQDYERLGVNDYLKVYWESARNQLISGGASPEQAGMAAAQNLISGTLGFNPFNV
                     PDDQVVDANGVLNPNATFMWADDTDWEDAI"
     gene            17561..19720
                     /locus_tag="ACZPB4_01360"
                     /pseudo
     CDS             17561..19720
                     /locus_tag="ACZPB4_01360"
                     /inference="COORDINATES: protein motif:HMM:TIGR04056.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SusC/RagA family TonB-linked outer membrane
                     protein"
     gene            19733..21340
                     /locus_tag="ACZPB4_01365"
     CDS             19733..21340
                     /locus_tag="ACZPB4_01365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RagB/SusD family nutrient uptake outer membrane
                     protein"
                     /protein_id="HIR1096908.1"
                     /translation="MKNIYIVVLLSLVVLFNGCKEDFLETTSTQTVDEQAVFNDTQSA
                     MLAVNGLHKLMWTGDLSSSAFYGGYDMLMIWYEVMGDDLVYTYSNAQFQKQAQWSSHR
                     NATIGSATHFYRLLQYFISNSSMIIDNIDAAEGLESERNYIKGQAHFYRAFAYFTMVQ
                     MYGGRYKAEGDNTQLGVVIRNDNSTEPRARASVEEVYTQINEDIDLAIQLLGATEEKR
                     TNKSHIDLHVARGLKARILLTQGKWLEAAEMAKLVVDLSGAKLQDDTYTTLNDRFSDQ
                     SNTEWLWGSNPLLQQAPNLTHFHGYMSNEIISYNGNTPRAIYNKLYDKISDTDVRKGI
                     WFPRATDPNTLPRPIRAECNSKAYANYMANKFIVSDPTTKGGRDVPFMRLPEMMLIMA
                     EGYARAGEPGKAAQALYPLASHRDPEYTLSTKTGENLIEEVMTQRRIELWGEGFRWFD
                     LKRLNMDLDRGPAPRPEVFPNGLIEYWNKDAMPKVVDPEASNYNMYGDGTVTGNGNRY
                     RPAGHRDWQWAIPDKETQLNPLCEPNP"
     gene            21356..23938
                     /locus_tag="ACZPB4_01370"
     CDS             21356..23938
                     /locus_tag="ACZPB4_01370"
                     /EC_number="3.4.17.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004181 - metallocarboxypeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M14 family metallopeptidase"
                     /protein_id="HIR1096909.1"
                     /translation="MRRFFLMCLLPIFLATGVFAQPQADEYPYDLTYFLPEGSQVYDP
                     QVPTPEKILGFQLGEQHAGWDQVVEYMRTLARCSDRVTIRETGRTYQHRPFIEVVFTS
                     AENQKNIDRLKEEHLKLSDVAKSRSVVIDDMPVIVSLIYSIHGNEASGVNASLAVAYH
                     LAAAQGPEIEELLDQEIVVMTPGANPDGINRFASWVNSSRSFTNVSDIKSREFTEPWP
                     SSRTNHYWIDCNRDLLMAQHPEGINGLNGYFEWLPNVVVDQHEQGALRPYYFSPGHPK
                     RTHPFTPQLNQDLTAEISSYTAKALDRIGTTYYSKEGYDDFYYGKGAAYGDAHGSVCL
                     LYEQGSTRGHLRNTPSGEWTFGWTIRNQALASCATLEAAKAMRTRLLAYQKEYYERTA
                     SEARKEAVQGYVFDTRGSKSVAFHFLENMARHHIEVYQLAKDYQAAGNKEFQKGSAYV
                     IPVAQKYSTMVKVLMEDCLEYTDSTFYDISTWTFPHAFNLECAPVKSVAGLMGDRIER
                     NDFPQGRLIGGESRVGYVFENREFYAPKVVYELQRKGIRVSATNRPFQFKNEEGEWTM
                     GYGTYQVLTHNQPLPSDVLYATLDELAKNTGVDIYSANTGLMADVDFGSPAFKPLEQP
                     KVVMLVGRGVSIPESGEIWFLLDKRFQMRPVLIENPSLTGKDLKAYNVIILANGVPNL
                     TKGTETALKEWVAAGGVLIATGKASAWAGKQGLISLKTKETLLEKADSLSVYRSFADK
                     AEAKAGKLIKGVILNCHLDKTHPLAWGLDQDEIAVIKTNDIIFQKDRDPYVSPLYYTK
                     KPLLSGFLSADNANLLREEPAIMVKPYRSGKVIVFADDMNFRSYFFGTSKLFMNALFY
                     NKCM"
     gene            23976..24674
                     /locus_tag="ACZPB4_01375"
     CDS             23976..24674
                     /locus_tag="ACZPB4_01375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010182276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1096910.1"
                     /translation="MALVLSGAMEFANACTSAIISGKVTPDGRPIMWKNRDAENLKNC
                     VRSHLSRSFHNPLMGIDLKDGKHNKPETSSWFAEQDFIARRSTSCAVAIQGVRPDEDA
                     SFTTMWTVIGYPPVTPAVPVWLKGADKKLPKALTVDQNKHAPLCDASNMLRDKIYSYH
                     RGTNTESYFHWELLFNLSGNGYMQQTERLEEELFERFYSSIETWRSRSVIPEELVFNL
                     YDDCDAFLDEKTLR"
     gene            complement(24697..27060)
                     /locus_tag="ACZPB4_01380"
     CDS             complement(24697..27060)
                     /locus_tag="ACZPB4_01380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1096911.1"
                     /translation="MESISLKLIFRSWWRNKTFAVISLLSLAAGITCTNLLISYVIYE
                     SRIEAHNPNKSHIIYMAQDSPLTSGEKVSFIKGKIPVQLKDQYPEVEDYLRLNIDNAA
                     SITIEEKRFNPISIVRADPSFPRFFPYKVVAGDINKALTQPNAIALTEYQAKIFFGNE
                     DPIGKTFSAKYAYENETITYEVAAVIKEYPQSFLKFNALAGTTSQFNGGPTLLLVNDL
                     FNIDTFTQKLKDDKVPTFNGTGQYYFYTLQESYFQEQTYTQEYIPYIHRNQKDLLYVG
                     LFSAILILVIACFNYANLSFSRILQQVRMIYTQKVMGASAGQIHRQLFLDTFLTVLIA
                     FFLSLLLTLDFLPAFNQIVSGRISLGFFFSGQVLPVIVALILALSIIPSLYMSHKINS
                     LSHSEYKSFTTGTRKRTIISGLSILQFAISIALVFATLTVRQQLTLTQTNGERYRDLI
                     EIADWSGNHIQTFSEEIRRYPSIEEMCLSRSGIIQFNLRTMVLKDENGNELNYTLGQY
                     EGDSTFLKVMKINILQGLSEREALKQYSTPVYINEQYARLLVPKGENPVGKPVRLYDT
                     EFGKMEKEGEPIAIIAGIVENLYTGTLRQEVYPSLTYLTHTPPYNLVQVRLKKEHRAE
                     ALTLLQQTWEKINPNVPFEYQDIYEEFMLSNRKTIELAHLLIMYSIISLLLTAFGLFG
                     MALYAIQQRTKEIGIRKVNGATAGEILYLLNRRFIGWVGIAFAIAVPITWYSLSCWLE
                     NFVYRVDISIGTCLLSGGIVLMVTLLTVSRHSYKAASRNPVNALQSE"
     gene            27218..27994
                     /locus_tag="ACZPB4_01385"
     CDS             27218..27994
                     /locus_tag="ACZPB4_01385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HIR1096912.1"
                     /translation="MRNAKIIVVDDNEAVLRSLRTILSHEFKTIVTVSSPVLLPALLR
                     NGDVDMVLLDMNFGAGKQSGGEGLFWLDRILELKNPPAVILITAFGDIELAVSSLKRG
                     ASDFIVKPWDNEKLIQTLVHVWEHRMESNTDKASSVAESLINALLKKYTEAYAKPLPR
                     LTAEAVDKLSDMAGRGDLALLQQIVERTVLLVDKCRLDADDFYVEELSEVSHPCTLED
                     MERQFIAEVLKEKKGNLTLAAQQLDISRQTLYNKMRKYGL"
     gene            28013..28990
                     /locus_tag="ACZPB4_01390"
     CDS             28013..28990
                     /locus_tag="ACZPB4_01390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HIR1096913.1"
                     /translation="MVNRSLYLKIIGIVSLIVFLVLLGSVLLITGTSYFLSFVCLCII
                     LLITLLLIRWMNGINRKIATFFESVRNGDTALRYPNKTNDPFVKDLYTEMNRIILLFS
                     QNQSEMEEKRLYYESILRVLTHEIRNSITPIRSLSADLLKYSDTYTPKQLREGLEVIH
                     GQAQNLSAFLDSYHRLTHLPEPERTEVPITSLFQKMERLLCAEPGSDRIRFSSAEALT
                     VRVDQNLIVLALINLIRNALQAIEGQADGIVSVEALKTDGRVYITITDNGPGISPELL
                     SAIFTPFFSTKSGGSGIGLSISHRIMRLHGGDLTVDSLPGVRTEFRMKL"
     gene            complement(28999..31701)
                     /locus_tag="ACZPB4_01395"
     CDS             complement(28999..31701)
                     /locus_tag="ACZPB4_01395"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009016877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HIR1096914.1"
                     /translation="MMRHLKYLAFVACLGSLSPAFAQNASKSLTIDDLVTWQRITDRE
                     ISDNGKWVACKMEPWEGDATVYLYAAQGQETATFSPADKFAFSASSGYLVVTQTPGKS
                     TVDSLKVLKTKEDKMPMNTLVIYSVAGKKETIDSLKTFKLADEADWIAYQRGRKDSTL
                     YVRSLDGSKTFQFPTVTDFQFAKKSGMLYYTSAAEGEAGIFTLNPEKGSPALIKKGKG
                     VFKQTTFDEKGERLAFLYCADKDSSYKALSLWLSEHNAPAKEIATRGNRAFPAEWVIN
                     ENGMLQFSKSASRLFFGTSPEPRQKDTTQLAENRPNVQVWSWDEPVQYTVQNYNKEKD
                     LKKGYQAVYNLGNGSIFQLANEELPNIQLGNEGDAPLALLSTSRPYSLSSMWEARTRS
                     DYYTVSLDNGERKQIAQADYGRFRLSPQGKYAYWYGETDSCWYTIALAEGKQYRLTTP
                     ESFPAWDEENDVPNHPYAHGAAGWTANDQNLLIYDRYDIWKFDPTAATPPINLTVNGR
                     KEKLSYRLEQLDKEARFIDLGKPQLLKGFNEATKGYGFYNARLSAPAAPKTLLAGNYM
                     LRSINKAKNTDDVIYTMETFQQYPDIHYSTLAFKKSVQLTHGDKQQEGFIWGTAELVS
                     WISLDGRPLEGVVYKPANFDPNKKYPMMVNFYERNSETLYNYRMPEPHRSTIDYHLYN
                     SNEYVIFNPDIRYVDGYPGESCYNCLMPGITMMIAKGYINEKGIGAQGHSWGGYQVAY
                     LATRTNLFSAIESGAPVVNMFSAYGGIRWGSGMARSFQYEHTQSRLGATPWSSPLRYL
                     ENSPLFTMDKVQTPILIMHNDADGHVPWYQGIEYFVAMKRLGKPCWLLNYTGEPHWPM
                     HMANRIDFQRRMFQFFNHYLKNQKMPKWMSEGVPAVEQPFELGY"
     gene            32495..35248
                     /locus_tag="ACZPB4_01400"
     CDS             32495..35248
                     /locus_tag="ACZPB4_01400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6383 domain-containing protein"
                     /protein_id="HIR1096915.1"
                     /translation="MNKRISTLFASFLLMAGAVFAAGETTPAKTYEALGKVTNGEKVY
                     LGADPNEDTKVVTSFLKSEEVKNVGYGFTTVDEAGAEVFTVSGKKTENGTDYFQLLNA
                     AGKVIYGTTSGDVVGTPDADAVKKGYCWFTFAEGVIKLGNKPLAYDMSSSSKVAKMLK
                     ASKETTVDDLNKNLSGKGFSFKFPKAASEPDVNPFGEQMFAIDAATVNEQLELGVESV
                     SGVCFVVANDAGLKLAKSDGKTKDNLKAATFIVLNPNAIFGITSLDATQGEGFGFTTV
                     KGEKLNSTNVKKDGKIAFVNAIYSVSEKDLANKGGQYTVQMKGVKVTKDTDENHGSNL
                     NVYVGAYSLTAGGLKTYITTKKDEAKLTLAQTTGDTWAKASDLLKTDGAAIYNIYFTG
                     TQPESGKENESLYGKYLVSKYAAKADVARTNSYSFVEEAVAPKDVDLKAPSAQWVVIA
                     MPGMGSVTFKNLETSETFKANLYKTDKAGIYQAVSTTVGELTAENIKLVAVSGNEGFL
                     NLTDAQLKQKAQLVFNGKSAVAVDKLYMYYNDDAKKKQFEPISDVAKSYSWAFEKAES
                     VKNNFKYIYLKDDAVAEKEADNYNQVVKAGAKRLYVDVTEASFSEDLVGADKSYTNVT
                     VDFYQLGISLEATPRHATLDGDEGSISLKENKNGILEGVIGAEGLTFWLDTADSKAEI
                     PSFYISKGIATEEPVTKAEEPAAVTRNFLYYAKDSMYFWNESKAKFDVNANYALEGSY
                     SNDPTEETDVKAIFRPAVLAGVDTINTTVNGKAVVVAKETKENVCSAGIDNFKFYITK
                     IEGGYSVTPVGAATTYLYALNGKLGFTTNASKALPLTVGEGNPTSNESIDNSVSSSIV
                     VTGNAGYVTIQGAQGETAYVRNLLGMPLAETVITSDDATIAVPAGIVLVTVGEETVKV
                     VVK"
     gene            complement(36081..36329)
                     /locus_tag="ACZPB4_01405"
     CDS             complement(36081..36329)
                     /locus_tag="ACZPB4_01405"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1096916.1"
                     /translation="MKKINYYYLVAGFLALLFSITHELNGQRALIPALYAGELDINTV
                     TTFKYIWHIITAENSVFGIAFIIMAFYKEQEKVKFTAC"
     gene            complement(36392..37165)
                     /locus_tag="ACZPB4_01410"
     CDS             complement(36392..37165)
                     /locus_tag="ACZPB4_01410"
                     /EC_number="2.1.-.-"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HIR1096917.1"
                     /translation="MSNKNKTIHEFDFNLICEYFSNVERQGPGSPEATLKALSFIDNL
                     ADNSRIADLGCGTGGQTMILAENAPGQITGLDLFPEFINIFSRNAKQSDLSDRVKGVV
                     GSMDDLPFGKESLDLIWSEGAIANIGFKKGLNYWNGFLKKDGYVALTYESWFTDDRPA
                     EIEKFWLDAVPEMNTISHNISVLQKAGYRLVAAFTLPETCWTEHYFSPCSKIQDEFLK
                     KHTGSKTAEELIAGQRHEKVLYDKYKEFYGYVFYIGKKI"
     gene            complement(37184..37753)
                     /locus_tag="ACZPB4_01415"
     CDS             complement(37184..37753)
                     /locus_tag="ACZPB4_01415"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIR1096918.1"
                     /translation="MNLNNIQIRETATSDFSHIMEVEKLAFGYDKEAELVAELLADNT
                     TKPIVSLLAFYKDEPIGHILFTRAYFNEHQQQPMMHILAPLAVKPEYQRQGIGGMLIK
                     AGIEKLQEKGSNLVFVLGHKEYYPKYGFIPDANHLGYPAPYPILEEYSDYWMVQPISP
                     KGFEIGKGKIKCSEELNKPEHWRNEESDR"
     gene            complement(38185..40581)
                     /locus_tag="ACZPB4_01420"
     CDS             complement(38185..40581)
                     /locus_tag="ACZPB4_01420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor domain-containing
                     protein"
                     /protein_id="HIR1096919.1"
                     /translation="MRKLFLSLVFLSVLLSIHANPGIKGIVIDQTTRKALDYAHVVLY
                     DGDHIVEEAMTEANGSFLIQPVKPGTYSIRIHFLGYDVYMGEEFILTEQIKDLGIIPM
                     QMLEVGLQEVEVVANKKQVIYKLDKKIIEASSNLLSSGGTAVDILENTPSIRVNAEGE
                     VTFRGSSGFTVYVDGKPSIFTGTQALEQIPSGQIQNIEIITTPSAQHDTGGDVGIINV
                     ITKKNFGEGLSGVINLSGNTVWSRTLDFLLTGQNKASQWRIGGYVGNRLRKSHFTQEK
                     TTLVNDTTTTSYSNGPRESNGYAYILNGGWSYTQKQTTFSINAEGGYAGLKRKGDLEY
                     TEERSANGEQFENGEFKSLDDFDIHETFGLGNLAVDHKFNDKGHNLSGSFFLKYGGDA
                     LEYFQSDLFDKNNVRQQGHRAWEAEHRWTVRAKADYVFPYSKTGQIKAGYQYFSYSED
                     GDYSMQFWNPDTKEFFWRDDIYNTFYFQQGINSLYAIVGDSYRSFDFQVGLRGEHTHQ
                     VLRSSKDWANRLQKRFELFPSAHIGYNLTQNQKLLFAYSRRTTRPELYFMEPYITYKD
                     YYTAEIGNPDIRPEYIHSFELNYSLTSGDNALSASLFHRTRKDKIERLRVPYQAGVTL
                     DSMANVGHDYSTGIELSGSLQATSWWNTQINGSLYHYRVENEYKTDGKNETSTNYEIA
                     WNNAFTAGKYTRIQLDGNFVGHSVTTQGRTQSFWFVNLAIRQQFFKRKLTATLSFRDV
                     FNTARYVNTITSSNLISKTRIRPDYPLIGLTLSYTFNQFKLKNGLSNNSKDLFEGTNH
                     "
     gene            40744..44853
                     /locus_tag="ACZPB4_01425"
     CDS             40744..44853
                     /locus_tag="ACZPB4_01425"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hybrid sensor histidine kinase/response
                     regulator transcription factor"
                     /protein_id="HIR1096920.1"
                     /translation="MRIYLLLLFVLMITRAQATNVIFDRITMDSGLSSSSVTSILKDR
                     TGYVWVGTTEGLNRYDGYTFKVFLPVPDCPESIQSSSIDKLFEDSDGGIWIFFSSGGI
                     SRYDRGSDTFLNFTKEWLRQQLRVYGSPTCFSASVPGHIFIGTENGMLEYDAKEKKLV
                     RLSPAGSVVSSSPVNCLYSAPDHSFWVGTLAGFSLYDKETNHFQDYTIRTNDREDINA
                     GNLNGVNAIYIDRFDYMWLGTGREGAFRSVDMGEREIFQSVGREDTRVYQFLETGDGD
                     FWIGHNKGASLISRMNRLALRCEHFFDRPEDLEPTGECQVRSIFESKDGTVWFDDSRF
                     NQGLFYYSPKERKMGQLRNVPEDAHSISSNQITCLFLDDSDHLWAGHSTYGVSHADLT
                     PSLFRYTLGYTEKENLSSLHILAVYEDSDLNLWVATSRGLDRINHKTSRVDMRFTFSP
                     RKSPSSLSGKIIGSIREDSERNLWISYQDANPDRLNLDDFRIRPFIPDYQVSYDYPIN
                     SLSELCNLCVSEESWFWGGADEGRLRVWDTKTRALITYRYIPGEMNPLASNHIHCLFV
                     DSSGYLWIGTNAGLDQYDKRTGRFDHFTVQDGLSGNIVRGIREGEPGILFVSTNKGLS
                     RLDIQNRHIVNYTTANGLLSNEFMGGACCKRKSGELVFGSNEGIVSFDPVQLTDGLRK
                     IPESLRITNLTIGDSREKQGLQVGFIAFDYSHPRSIRYRYRLDGYDTDWREVDASDRT
                     AIYNRLPPGNYVFRVETSGNGSYWSAPITEPVRIFPPWWWTWWFILLVFVVVCVLLCI
                     AYKSRVRWYQLRQAELECKILERTRLLKQAKQELEEKDALKTRFFMNVSHELRTPLTI
                     IKGLTEDLERHSGSEESCGDKEILRTISRNTNRLIRHVNELLDLSVLTRGVPSPHIVC
                     ADLSRFLEDISETFIPLADSYKIAFTYSIAPDISIAYFDKNILEQVLYNLLSNAFKYT
                     PDGGSVSFSASLEQSSSDAVMTLRITDSGIGIPPESLPYIFDRYYKGASIAFRRSESS
                     GIGLAYTKELLELHKATIQCESELGKGSVFTVALPISEEAYPEEWLEYSEPKMEEVSL
                     RESVPLEETNSVPENLRQTLLFVEDNEDLCRYLMNAFQTDYRVVIAKNGKVGLEKALE
                     ILPDVIVSDVMMPVMNGIECCEALKTDERTAHIPVILLTALAEERQQLEGYGAGADDY
                     LPKPFSLAVLKAKINNLLKRSERLKLYFRDRFDLRTPEQTVANPDKEFVSKVTRIVLA
                     HLQDPEFDVELFCSEMAMSRASLFRKLKSTTGCSASSFTRNIRIKRAAELLGQHAYSI
                     GEVAAQVGFSDPNYFTRCFKEIYGITPSEFIQTSPSSQDSHSPLASSGK"
     gene            complement(44792..46003)
                     /locus_tag="ACZPB4_01430"
     CDS             complement(44792..46003)
                     /locus_tag="ACZPB4_01430"
                     /inference="COORDINATES: protein motif:HMM:NF014717.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1096921.1"
                     /translation="MTGCLAGLYPAIRSTSYAPALVLKGSFGLSPKGKKVRVALIGFQ
                     YTVSIALIIVTLFMGLQNHFMTSSEQLGFNKDQVAIVNLTPEIYAKHKPQYIQKLKDY
                     PGIEDVAFSVYELSKEDDMIDLEYARHEDKDVFFKVFYASENFLSVMDIQVEEGRDFT
                     REDLNKAQSDYIINPAAERDFHLHPGDRFNDRTVLGVSKDFRFNSCRIASSPFVFALN
                     NDIPNPKLVSYIRFNSKTNLQEAVAHVRETLKEIDPTFPFEISFYNTILNNLYQKEQT
                     LGKLISLFGIMAILISIVGVFGLVLFETQYRRKEIGIRKINGATTGQILLMFNKTYIR
                     IVSVCFIISIPIAWMGTQQWLENFAYKTPLHLWVFIVAFLIILSVTIGTVTFRNWQAA
                     NENPVNSVKSE"
     gene            complement(46070..47179)
                     /locus_tag="ACZPB4_01435"
     CDS             complement(46070..47179)
                     /locus_tag="ACZPB4_01435"
                     /inference="COORDINATES: protein motif:HMM:NF024116.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1096922.1"
                     /translation="MKLMIRNLLYLFKRFKTAVVLNLFGLTIAFAAFLLIVMQVDYEM
                     NYDAMHSKSSRTFRLEANHGEFEHNAIHCLMFSDAFVNSSAHITDYSYRYPFYGGERY
                     CQIDEVDDQGEAKVFKENFQLCLPNISDVFDFHMKEGSVGCLSIPGSVLIPESVAKRL
                     FDKQSAIGKRIRMSGSSGWQPVSTTILTIGGVYKDFPGNTTVQNRIYVPMDQLDLLKS
                     SWQMYANEIYVTLDDPLNKEEVLDHFNKTFDFAKSQMGSAQEIALRLTPLKDVYYTHD
                     TTFDFNPKGHRETNYVLLGIAFLILFIAGINFTNLTTSLIPLRLKTINTHRVLGCSIY
                     KLRAISLIESIVICLISYILALFIVNDLSYTPIAN"
     gene            47393..48166
                     /gene="nudC"
                     /locus_tag="ACZPB4_01440"
     CDS             47393..48166
                     /gene="nudC"
                     /locus_tag="ACZPB4_01440"
                     /EC_number="3.6.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000210 - NAD+ diphosphatase activity
                     [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) diphosphatase"
                     /protein_id="HIR1096923.1"
                     /translation="METSNRLCYWFLFYKDQLLLQKENDTYTIPYGENPPVPVSHTLE
                     VDYRDGLPARTAELDTPVEGNDRYVHMGLRASWDYISRACYEKAGKAFQLLYWDSHSR
                     FCPVCGTPTVQTTSIMKQCPSCKHEIYPTISAAMIVLIRKEDSILLVHARNFRGTFHG
                     LVAGFLEVGETLEECVRREVREETGLEVDNITYFGNQPWPYPSGLMVGFVADYVSGEI
                     KLQDEELSSGAFYTKDNLPEIPRKLSLARKLIDWWLDHQ"
     gene            complement(48137..48742)
                     /locus_tag="ACZPB4_01445"
     CDS             complement(48137..48742)
                     /locus_tag="ACZPB4_01445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4858 domain-containing protein"
                     /protein_id="HIR1096924.1"
                     /translation="MRPLLIGFFVCINIHLGYAQWTEQDSIWLKDVLAGKDSIKLNPE
                     FQKAIQSGSFLNPEPGKPMGKPQLAAPSNIPITKDFSEYIQQDDTTHRKVALKDLPPS
                     VFWRHNPPYKKILPVYQSILDELKRTPSSGRTSLATFDLGRMTSRKTYVHKRNAKRNG
                     TWQNYGNLPTPDVISKRKKFERQQAEAAKKDSSLMIQPPID"
     gene            48959..50323
                     /locus_tag="ACZPB4_01450"
     CDS             48959..50323
                     /locus_tag="ACZPB4_01450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent transcriptional regulator"
                     /protein_id="HIR1096925.1"
                     /translation="MKKGKLLIIDDNEDILFALNLLLEPYMEQIRVATQPERIDHFMR
                     TFIPDIILLDMNFKRDAISGQEGFYWLEKIKKIDPDVVVLFMTAYSDTDKAVRAIKAG
                     ATDFIPKPWEKEKLLATLSSALELRESRAEVRNLKKQVEILSSPEDAGFEIIGESEPM
                     QAIFATVDKLKNTDANILILGENGTGKDLVARALYHQSPRSGNLFVGIDVGSIPEQLF
                     ESELFGYEKGAFTDARKEKPGRMEVASGGTLFLDEIGNLSLSMQAKLLTALEKRQITR
                     LGATQPIPIDIRLICATNVNIHHLVAEGTFRQDLLYRINTIELHIPPLRERGNDVILL
                     AEHFLSKYARKYKKDLKGINRDGKNKLHNYAWPGNVRELQHAIERAVILSESNWLRPE
                     DFILRSVPLRDKEPSDELNLTILEKEAIERALRRAEGNITRAAELLGITRFTLYRKLE
                     KFGL"
     gene            50320..51327
                     /locus_tag="ACZPB4_01455"
     CDS             50320..51327
                     /locus_tag="ACZPB4_01455"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1096926.1"
                     /translation="MIRYLLFARILGIVVLSFTASFLMLKGFLFIPALFGFCILALSV
                     FLYKDQQKTVKRMEYLIESIHYGDLSLFYPSDSMTEDEKALASSMNAALEALRSRLYN
                     SVVAEAETEAWQKLIRVLTHEIMNSIAPVISLSETVAERATINGMNERDYAIMVQAMQ
                     TIHRRSKGLLDFVENYRQLTRLPLPTLRNFSVSALFDDIRLLFPEKSDILFFRVKPED
                     LNLYADRIMLEQVLINLLKNAIEACEESLSPQIVVEAVQKAGMVIISVIDNGSGIVPE
                     AIDKVFVPFFTTKSKGSGIGLSLCRQIMNRHGGSISLDSQVEKGSSFVLRFPIVTKRI
                     L"
     gene            complement(51322..53970)
                     /locus_tag="ACZPB4_01460"
     CDS             complement(51322..53970)
                     /locus_tag="ACZPB4_01460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HIR1096927.1"
                     /translation="MTLLKYYIRFVLFIVLSLVFSFHLYATDNAGPILIISSYNPDTR
                     NTTANISEFMEEYKRGGGISPVVIENMNCKSLPEAPLWDGKMRGILDKYKENNTPQLI
                     IILGQEAWASYISQEYKPDIPVLCGMISKNAILLPDSDLNVAEWEPKYIDIQEYVDKG
                     LHLGGFLYSYDVKENIRLIRKLYPQTQNIALITDNTYGGLAMQTLVKKEMENIKDLNL
                     ILLDGRKNNIYTIVEQIKNLPDQTVILIGTWRVDVNDGYYVGNATYTMMTANPRIPTF
                     TLASVGIGHWAIGGFSPKYRPIGSDLAKEALSILEKKIAPKDIHPQIIPNGYMFDASK
                     IKAFDISRLSLPHDATIINEDPSLFSKYRFEILLSVITVLFIFLIMILIFFIRTNKLK
                     DKLLDLQKDNILIMNNIQASIYFIKPDYTVKWRNEVEFHDCIPEFGPANCFLVKNGVK
                     PYCTRCTVAKAMETKKQVDITNEFGDGKYLHILANPVLDEHDNLIGVIFKKEDVTKQK
                     QAENELRKAKEKAEESDRLKSAFLANMSHEIRTPLNAIVGFSGLLAVTENMEDKEEYI
                     NIINSNNDLLLQLINDILDLAKIEAGTLEFVDSDVDVNQLFSDIEQSSRLKAQDGVQV
                     CFVEKIPNCILRTDRNRVSQVITNFINNAIKFTTQGSILFGYRHRDDELYFYVKDTGC
                     GIAKDKIGQVFTRFVKLNSFVQGTGLGLSICQMIIKRLGGDIGVESEQGKGSTFWFTL
                     PYSILEMQEVPHEKPKTENVQKSQSSKSATLLIAEDNESNYTLFQAMLKDYNLIHAWN
                     GEQAIDLFNKYQPDLILMDLKMPIVDGYEATRVIREKSQSIPIIAVTAFAFAEDEERV
                     KQSGFSSYIAKPIKPDKLIACINTYL"
     gene            complement(54103..56496)
                     /locus_tag="ACZPB4_01465"
     CDS             complement(54103..56496)
                     /locus_tag="ACZPB4_01465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HIR1096928.1"
                     /translation="MDRRHLYFLLFLLCTIQAAIGQQRSFSIKGVVKDASSGQPIPFA
                     NVVVWNTTQGAVTDSTGLFEISGISPGSYRLQSSFLGYKPFVTAEFRLANKDIFFPIE
                     LEEASQNLQEVSVVASPFRKTAESPLGLRVIGFKEIEKSAGGNRDISRVVQTFPGVAS
                     TAAFRNDLMVRGGGPSENRFFLDGVEIPNINHFSTQGASGGPVGIINPDFIREVNFYS
                     AAFPASKGNALSSILDFKLQDGNKEKFSLRGVLGASDIGVSANGPLGKKTTYQVSVRR
                     SYLQFLFDMIGLPFLPTFTDAQFKIKHSFNPKNELTVLGLGAIDDMKLNTGMEDMSEK
                     NQYILSYLPVVKQKTYTLGAVYKHYAGKNLYSVIISRSQTNNKNIKYKDNDESKEENL
                     SLNYRSDEIENKFRTENTFRLPFIQLNVGGNIEYAQYTNDTYQKQFTSIPRTIVYQTD
                     LGIWKWGIYATAIYESYNERFTASLGVRADANNYSSDMNNLLDQLSPRLSLSYRLSDP
                     LYINANIGRYYELPPYTTLGFKDNEGNYVNRTNHLSYIRSDQAGLGLEYRPTSYLKFT
                     TEGFYKHYDRYPMSILDSIPLASKGTDYGVLGNEAVSSTATGRAYGLEIMGRWYNYKG
                     LTFIASYTLVRSEFKDGRNMDTYLPSAWDNKHLFTFSGTYSLPKNWDVGAKFRVVGGA
                     PYTPYDVEKSSYVEAWDANNGLYYDYSRFNSERLKPFTQLDIRIDKTFYFKKIMLGAY
                     IDIQNILNSKYKEQDVYIKTGKIINPEAPIYEQRYELRPIERLTGTLLPSIGVMIEL"
     gene            56567..57229
                     /gene="mnmC2"
                     /locus_tag="ACZPB4_01470"
     CDS             56567..57229
                     /gene="mnmC2"
                     /locus_tag="ACZPB4_01470"
                     /EC_number="2.1.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004808 - tRNA
                     (5-methylaminomethyl-2-thiouridylate)(34)-
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase
                     MnmC2"
                     /protein_id="HIR1096929.1"
                     /translation="MEKELQITADGSHTLYIPAMDEHYHSVNGALQESRHIFIEAGLH
                     AQEKDFIRIVEVGFGTGLNAFLTLKDVELSQAHHIDYHTVELYPLPLDTIRALNYGEL
                     IWPERKELFLALHEAEWNTPVSISERFTLHKIEGNSNACELPDDIDLIYFDAFAPEKQ
                     PEMWNQEIYNRLYAHTAPGGVIVTYCAKGEVRRGMQAAGFEMSRLPGPPGKRHILRGI
                     KN"
     gene            complement(57290..57607)
                     /gene="trxA"
                     /locus_tag="ACZPB4_01475"
     CDS             complement(57290..57607)
                     /gene="trxA"
                     /locus_tag="ACZPB4_01475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HIR1096930.1"
                     /translation="MALQITDANFEELVNSGKPMVLDFWAEWCGPCRMVSPIIDELAT
                     EYEGRVTIGKMNVDENDDVVGQFGIRNIPTVLFFKDGKMVDKVVGATAKDKFVEKIEA
                     MLK"
     gene            complement(57695..61498)
                     /gene="dnaE"
                     /locus_tag="ACZPB4_01480"
     CDS             complement(57695..61498)
                     /gene="dnaE"
                     /locus_tag="ACZPB4_01480"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005637647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HIR1096931.1"
                     /translation="MEPFIHLHVHTQYSLLDGQASIDALIDKAYKDGMRAIAVTDHGV
                     MFGIKEFFNKVSKKNSKPLGIIKDSEKELKPLLAKDAPTDEEQQRITELQKQIAEAKA
                     SIFKPIIGCECYCARNGRHSKLASQDDRSGWHLIVLAKNKNGYKNLIKMVSLSWTEGF
                     YGRPRIDKELLEKYHEDLIICSACLGGEIPQHIMHGRIDKAEESIKWFKNLFGEDYYL
                     EMQRHETHDPNADCTIFPHQQEVNKVLIELAHKHNIKLIATNDVHFVNADDAEAHDRL
                     ICLSTGKDLDDPKRMRYSKQEWMKTTAEMNTIFADIPEALSNTLEIADKIEFYSIDSG
                     PIMPTFAIPEEFGTEESYRQKLTEHDLFEEFTRDENGNVVLSEEEAHSKIKKLGGYDK
                     LYRIKLEADYLAKLTYDGAKELYGDPLNDEVKERLNFELHIMKTMGFPGYFLIVQDFI
                     RAAREELGVSVGPGRGSAAGSAVAYCLGITKIDPIKYDLLFERFLNPDRISLPDIDTD
                     FDDDGRGEVLRWVTEKYGAERVAHIITYGTMATKSAIKDVARVQKLPLSESNRLAKLV
                     PDKIPDMKKFKLGDAIKYVPELKEAANGNDPLARDTLKYAQMLEGNVRNTGVHACGVI
                     IGRYDISDVVPVSTAKDKDTGEEMLVTQYEGSVIEETGLIKMDFLGLKTLSIIKEAIE
                     NVKLTTGHDLDIDHISLEDPKTYKLYCDGKTTGTFQFESAGMQKYLKELQPSKFEDLI
                     AMNALYRPGPMDYIPSFIARKQGKEEIKYDIPVMERYLKDTYGITVYQEQVMLLSRLL
                     ANFTRGESDALRKAMGKKLIEKMNHLKSKFMAGGQANGYKEETLNKIWSDWEKFASYA
                     FNKSHATCYSWVAYQTAYLKANFPSEYMAAVLSRSLSNITDITKFMDECKAMGIQVLG
                     PDVNESILKFSVDKNKNIRFGLGAVKGVGESAVQNIIEERKKNGPYKSIFDFVERVNL
                     TACNKKNIESMALAGAFDNFGIQREQFFTDSGKGELFLDTLVRYGNKYQMDKSTAVNS
                     LFGGDALIAIAKPEIPQCERWSDLERLNKEKELVGIYLSAHPLDEYRIILKYVCNTGM
                     VELNERETLQGREVLLGGIVTGFREGMTKNGKPYGILKIEDFTGSGEIPLFGQDYIEY
                     SKYGKIGMYLLITARVEPSRWDPNKLDFKIGTVNLLQDEKDKLIEKISITVPIHDLDE
                     PTINELSVLIKNNPGHSLLYFKVVDGEHNISLNLFSQNIRLNVTRELVDFLQENENID
                     FKING"
     gene            62305..65514
                     /locus_tag="ACZPB4_01485"
     CDS             62305..65514
                     /locus_tag="ACZPB4_01485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6383 domain-containing protein"
                     /protein_id="HIR1096932.1"
                     /translation="MNRKISTLLTAGLLVAGSLCGSAFAQNSIQSLLGLGSAVTELKS
                     GAYVMTDANGLAYGFTSVSEDGVLQEGILDYKATSIADDKKDDVKQYIWKVTVTENLG
                     AYSYKFENVATGKTLRVNTTAGSEAVELNSAASGNVIKDVFAFGATQIGTTGKYTASE
                     KALFAYNGNKSDVFQLKWSAGGSLISTTASSFDLSFYAVESEELGAVGADELNDLYNT
                     AGFSFVSKRLDSDQTSEPNGNLFNEKRIVARYVPSDLRVDATSYPSYSGSTADLKIPA
                     GMYFFTENAPDKDDCSGVNAVSSGYKAWMDATVLVLSSTETVEGTNAGRASGDGFMLV
                     EKKISELNLYQGTSSNWKAAGDEISINNANFRVQKSYSEGYPYELNVDRFRYRKQASK
                     ADQADAKVKLHILKHNDNYYLATASTLTDASNNPINYFIFKQGAAGMKSGIELLNTEA
                     KVSAYTIRVLDGKGVDKKDIKSVYGKYLTNAVKRGSFQFVAKAKVLSQLETPAYQWAI
                     SSVDDTYKVTFTNRETGEYFQASLFPKTDLGENVYELATDNKTVTAIYVNENTYREAE
                     GDDADMQQLIVELTPAEVDPYAGFLNVDNETLVTMAFARDNNETSNKWYVAATENNLS
                     LATSEYILNKNDKFANEVSGAAQWQLVKEDNKRTIIERSFVYNKDGRVTVQARGDKAY
                     AYVYRLQYINDGIETEEYFPAGSSNVSAQEELVDENNTTRFVIKQAADGSVYLIKVTS
                     TSSNIASILNANTTSVVDATYKASIDECQYTTPSSVYAWPIATTPSGQQDWLLNTYLI
                     VEAPEISYPAEEGHISLISEMNNYISMNEDRDGIVVNENQYSFYLQVTDKDAVVPSFY
                     ISNKGTVEDGNRLFLFNPKDSVNYYVADGTYDRKYQWNEDDTKAVFKPATLWESKDTL
                     TTIVKGNKVAVAKEADDEGVLGGLDNFKVQIIQCEDDENAYRIRSVADKGSYLYGVND
                     KLSWSGNKKNAMRFTIAAGDPTSNESIADAAEGIKVIAGNGTIEIQGAAGKMVSVTNV
                     LGKSIANTVLTSDNATIAAPAGIVVVSVEGEEAVKAVVK"
     gene            65847..66479
                     /locus_tag="ACZPB4_01490"
     CDS             65847..66479
                     /locus_tag="ACZPB4_01490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008777864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0015288 - porin activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="porin family protein"
                     /protein_id="HIR1096933.1"
                     /translation="MRKIGLLLIAVMMILPAMAQVSFGVRAGGAYSSLIQKVEDTYEA
                     GARFGFSIAGLADIPLSKNKKWSLRPEVAFVNQGGAYYSNQDIHGMALHNKCWYYSLQ
                     IPVNVAYTFTFTDVHLSVFAGPTFDWSLFGKMKSRETNPDLHFGVSEEKDLKPCDFGM
                     NVGLSVEYSNFFFSVSSLCGMIDRRALKRDGETSVYQNNVTFSLGYYFRK"
     gene            66675..67130
                     /gene="rplM"
                     /locus_tag="ACZPB4_01495"
     CDS             66675..67130
                     /gene="rplM"
                     /locus_tag="ACZPB4_01495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008650448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HIR1096934.1"
                     /translation="MDTLSFKTISANKATVNKEWVIVDAEGQTLGRLCAKVAKLLRGK
                     YKPNFTPHVDCGDNVIIINADKVVLTGNKWNDRIYLRYTGYPGGQIEYTPADLLKKGG
                     DRLFRKVVKGMLPKNRLGAKLLNNMYVYEGTEHKHEAQQPKLIDINSYK"
     gene            67136..67522
                     /gene="rpsI"
                     /locus_tag="ACZPB4_01500"
     CDS             67136..67522
                     /gene="rpsI"
                     /locus_tag="ACZPB4_01500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013545814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HIR1096935.1"
                     /translation="MEVVNAIGRRKAAVARVFVSEGTGKITINKRELEKYFPSSILQF
                     IVKQPLAKLNVAEQYDIKINLDGGGFKGQSEAARLAISRALIKINPEDKAVLRAEGFV
                     TRDPRAVERKKPGRPKARKRFQFSKR"
     gene            67663..68499
                     /gene="rpsB"
                     /locus_tag="ACZPB4_01505"
     CDS             67663..68499
                     /gene="rpsB"
                     /locus_tag="ACZPB4_01505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HIR1096936.1"
                     /translation="MSRVNFDQLLEAGVHFGHLKRKWNPAMAPYIFMERNGIHIIDLY
                     KTVAKVDEAAEVMKNLAKQGKKVLFVATKKQAKQVVADKAASVGMPYVIERWPGGMLT
                     NFPTIRKAIKKMATIDKMTKDGTFDNLSKREKLQITRQRAKLEKTLGSIVDLTRLPSA
                     LFVVDVMKEHIAVREANRLGIPVFGMVDTNSNPNNIDYVIPANDDATKSVEVILGAIC
                     EAMNEGLQERKAEKIDAEAAEEAPKRERKAKAAVKKERTKKEDDDALNANVAGKFAKD
                     EE"
     gene            68644..69633
                     /gene="tsf"
                     /locus_tag="ACZPB4_01510"
     CDS             68644..69633
                     /gene="tsf"
                     /locus_tag="ACZPB4_01510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009037828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor Ts"
                     /protein_id="HIR1096937.1"
                     /translation="MAVTMADITKLRKMSGAGMMDCKKALTESDGDIEKAMEIIRKKG
                     QAIAAKRSDREAAEGCVLAKKDGEFAAIIALKCETDFVAKNEDFVALTQAILDAAVAN
                     KCRTLDEVKALPMGKGTIQEAVTDRSGITGEKMELDGYCVVEGAYTTVYNHMGKNQLC
                     TIAAFNKESEEAAHNIVMQIAAMNPIAIDEAGVPESVKEKEIQVAIEKTKAEQVQKAV
                     EAALKKAGINPSHVDSEAHMESNMDKGWITAEDVAKAKEIIATVSAEKAANLPQQMIE
                     NIAKGRLGKFLKEVCLLNQEDIMDGKKTVRETMKEIDPELQILAFKRFTLRAE"
     gene            complement(69789..70982)
                     /locus_tag="ACZPB4_01515"
     CDS             complement(69789..70982)
                     /locus_tag="ACZPB4_01515"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011108289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HIR1096938.1"
                     /translation="MTQVSDRLASLSPSATLAMSQKSGELKAQGIDVINLSVGEPDFN
                     TPDFIKEAAKKAIDDNFSRYSPVAGYPALRNAIVAKLKNENGLEYTAGQISCANGAKQ
                     SVCNTVMVLVNPGDEVIIPAPFWVSYPEMVKLAEGTPVIVPAGIEQDFKITPAQLEAA
                     ITPKTKALILCSPSNPTGSVYSAEELAGLAEVLKKHPDIIVIADEIYEHINYIGKHNS
                     IASIEGMKDRTVIVNGVSKAYAMTGWRIGFIAGPEWIVKAVNKLQGQYTSGPCSVSQK
                     AAEAAYTGSQEPVEEMRKAFERRRDLIVNLAKEVPGFEVNKPEGAFYLFPKCSYYYGK
                     TDGTRVINNADDLAMYLLEVAHVACVGGTSFGAPECIRMSYATSDENIAEAIKRIKDA
                     LAALK"
     gene            complement(71064..72281)
                     /locus_tag="ACZPB4_01520"
     CDS             complement(71064..72281)
                     /locus_tag="ACZPB4_01520"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003935 - GTP cyclohydrolase II activity
                     [Evidence IEA];
                     GO_function: GO:0008686 -
                     3,4-dihydroxy-2-butanone-4-phosphate synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HIR1096939.1"
                     /translation="MSEIQLNTIEEAIEDFREGKFLIVVDDEDRENEGDFIIAAEKVT
                     PEKINFMLKNGRGVLCAPITEERCQELELDMQVANNTSLLGTPFTITVDKLGGKCTTG
                     VSMYDRAETILALADPKTKPSDLGRPGHINPLRARSRGVLRRAGHTEAAVDLARLAGL
                     YPAGALIEIINEDGTMARLPQLIEVAKKFDIKIICIKDLIAYRLRTESIVENGVEVDL
                     PTEYGHFRLIPFRQKSNGLEHIALIKGKFEKDEPILVRVHSSCATGDIFGSMRCECGE
                     QLHEAMRRIDQEGKGVIVYLNQEGRGIGLMEKMKAYKLQEDGLDTVDANLHLGHQADE
                     RDYGVGAQILRHIGVTKMRLMSNNPVKRVGLEAYGLEVVENVPIEVKPNPYNEFYMKT
                     KKERMGHVLHNIK"
     gene            complement(72306..74231)
                     /locus_tag="ACZPB4_01525"
     CDS             complement(72306..74231)
                     /locus_tag="ACZPB4_01525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015920 - lipopolysaccharide transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LptF/LptG family permease"
                     /protein_id="HIR1096940.1"
                     /translation="MLQTFLPLFLMTFGICLFIVLMQFLWRYIDDMVGKGLGIPVLAE
                     MFMYAALFLVPMALPLAILLASLMTFGNLGERLELLAMKSAGVSLIHIMRPLIVTLLF
                     VSVGAFFFQNNVMPVVQVKLYTLLYSMRQKSPELDIPEGSFYKDIPGFNVYVKKKDPK
                     DGLLKDVMIYDYSEGFNNARVIVADSGRLKTSADKLFLVLSLFNGESFENVGKSQANT
                     TQARTAVPYRRESFSSKDILIEFDANFNRTDESFMQNQYMGKNLKDLQTSIDSMGIRL
                     DSIKDVNAKSIYDASYVKTLKSLRAKKESEAEGQPDEQQEKLPVITPTIQLDFDSLYL
                     AQAASSQAALLGRAKSSIENIKTDYYFRAATVGDEAYKVRRHLTEWHKKFTVSFACIM
                     FFFIGAPLGAIIRKGGLGVPVVISVILFIFYYIIDNMGFKMARDGVWDAWEGMWLSSV
                     VLTPMGIFLTYKAVKDSVILNADTYVNALKNLIGKREGRKVERKEVIIYTPDYEATLP
                     QLEKLVEESTTYLTNHKRWINYLTFWKQGGKDNTAELLAQDTENIVEELSNSDQNLLL
                     NKLMDYPVIGGYNNKLSKHINGKLALAIGIFFPLGLPIYLLATYQRKLLRHDIVMVQK
                     TSKELINMIYSLHLLKK"
     gene            complement(74334..74717)
                     /locus_tag="ACZPB4_01530"
     CDS             complement(74334..74717)
                     /locus_tag="ACZPB4_01530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="START-like domain-containing protein"
                     /protein_id="HIR1096941.1"
                     /translation="MKKEKFHIEYIFDKVSRRSLWNHLTTALGLSAWFADEVIINDNL
                     YTFKWSKEAQEATVIDSKPENFIRYRWVDEEDENAYFEFIIHTIELTGSTALEITDFS
                     EPGEKKDSINLWDSQVEDLKRTLGI"
     gene            74921..74994
                     /locus_tag="ACZPB4_01535"
     tRNA            74921..74994
                     /locus_tag="ACZPB4_01535"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:74955..74957,aa:Met,seq:cat)
     gene            complement(75709..76641)
                     /locus_tag="ACZPB4_01540"
     CDS             complement(75709..76641)
                     /locus_tag="ACZPB4_01540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FimB/Mfa2 family fimbrial subunit"
                     /protein_id="HIR1096942.1"
                     /translation="MKRGNFFANCVFAVSVILTVLSFSACTDDSNDVVATTSEVIEQA
                     EVPFSVVLKAMNSDGNDITTKGEVNGATLFVFDQNNDFFEQINVNKSTILSRRAIDIN
                     CPNSNDITVIAWSGINSGNEEISNMSKANIISDLQVSLKENNGIANIPSDLFYGQVTL
                     HKNSSTKSTVSNELQIIRKTSIFQLSTKGLIKYLGSNAGNFEYRIKNTKSSLDYNGNP
                     TGEEVEFAFPASFDEKGNLTTETQAIFPAQNITVELYKDGNLIFSSEKDKNGELFAAT
                     PGKRTEITFKYSGEVSANITIADWATVIQHITMN"
     gene            77204..79105
                     /locus_tag="ACZPB4_01545"
     CDS             77204..79105
                     /locus_tag="ACZPB4_01545"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hybrid sensor histidine kinase/response
                     regulator transcription factor"
                     /protein_id="HIR1096943.1"
                     /translation="MRSKGFKAKFMMAFWGLFVEAHYIAANNDTMEGSQGILPFIILL
                     IVSICVIAFLSYYMYRLKKENIAKGGELMARNDELLRSVDALSVKNREIQQMLVNKIR
                     ETDNWNRDNEVEREDLKKRLEEMEKLHNSFFVETIHEMRTPLSLVLGSLSELLQRKND
                     IDSSEATQLLSAYRNTLALQDLIEQLRNTRHGDDVANHLRIARYDMISITKQICDLFV
                     DWIAMNNVEFHINTQTSVLWVWIDRRKMEFALRVLLSNALKNTYRFGKISINISVVRS
                     NGKAYCSFSIQDDGLGESESTRLGLKQIVDMTESSGAIFEGISSEDETGTQYTILIPL
                     GRSHYMERAVEFIEPDGDLVKLNEMQKEEIAELIQVVPKKKETGKKMLVIDDSDQIRW
                     FLRHVFASEYHVSEAHNGQEGVEIARVERPDFILCDVMMPVKDGLATCREIKGIPELA
                     QVPVVLLTAKVESEDVIAGIECGADDYITKPFDVEVLRSKVNSLLKRRDEMRRFYTSS
                     PVGAHPEGEKTVKKDDSPSNLFMDAVISTIEKHLDDPSFEAKILADSLNMSLPTLYRK
                     IKLYSDSSILELTRMVRLKKAAELISMQRYSIQEVSEMVGFNDTATFRKRFTEQYGVT
                     PSQYMPGKN"
     gene            79448..80812
                     /locus_tag="ACZPB4_01550"
     CDS             79448..80812
                     /locus_tag="ACZPB4_01550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HIR1096944.1"
                     /translation="MKLRNLLFGTMIACAFAACSNEDDPIVGPDQPQTGENNATLTIS
                     VKNVARSLTKAAAEGTQTENEAKITNLTVALYDAETGALVASTSDIANEDAAADNDEV
                     QFAGLTEGAQLRAIAFANMPEISLAGTTIDNFVSPVYTMPAAGFAENYLPMSSGLSDP
                     FTLQAGKNYYGYTKTVGEGEHILVADPLYLIRNVARIDFTGLSLDMTRAAKDVYVEGI
                     ATIVPECVFIMHGRTKSNAADMGNGNSWWNVVSNTVWGNVSTTYAANATDYASGYRGD
                     FVNDDAMFTNMRGSIIEGYKASLPATALVQDIASEGAASASITTAPKFYVFENPQVKA
                     AREMNGADNFKPEDLATEIVVKGTYKLENAKKRGSNAVYNYEEKTAYWPIKIAATNEM
                     AAGTADYLNDGKIHRNIIYSIDATLAGRGYDDPTVPPTDFVELFVKTKVLDWGSANQS
                     SVVE"
BASE COUNT        21371 a        16206 c        19887 g        23649 t
ORIGIN      
        1 ccccatgagg attaaaggaa cgatctcgtt gggtttcaac ttaaagttcc gccctctcgc
       61 tttgatcatg atacccaata ccgggatcgc gaataaatat ctgaaaaata ggactgaatc
      121 cggattcata ccggctttat acaagggtag ggcgaacaag gggttcattc cataagtcgc
      181 tgcggcgata gcccctagaa catatccttt tgcttttgca ttcatgatta aaaatattag
      241 cgcgcaaaag tagtatattc atgataaata ttatatattt gtagattatc atttcaataa
      301 atcgttaact aaaaagtaat aaatatgcct ccagcagcaa gactgacaga tatgcataca
      361 tgtcctatgc aaaccccggc ttggccatca ccgatacccc atgtaggcgg tcctatcgta
      421 gggccgggag cgccgactgt tgtaatcggc aagctaccgg cggcggtaat gggggataat
      481 tgtgtttgcg taggtccgcc ggacacgatc attaaaggat cttccaccgt gatgatctgc
      541 ggtaaacctg ccgccagaat gggagatacg acagctcacg gagggcaaat cgtattggga
      601 tgtcccaccg ttataatagg tggttaggag gatctgcggc atataatata tgtatattgt
      661 gagaatatta ctatctttgc cgccacttga aaactaaaaa taacaagaca tggaaacagt
      721 agtaagtgga atcagaccaa caggtaatct gcatctaggc aattactttg gcgcggtaaa
      781 gagtttcttg cggatgcaag atgagtataa ttgcttcttc tttatcgctg attggcattc
      841 gttgactact cacccgcatc ctgacaatat acgaaatagc gtaaagacga tcctctcgga
      901 atatctggct tgtggtatcg atccggaaaa agctaccatt tatattcaga gcgatgtgcc
      961 ggaggtggta gagttgtatc tatatttgaa tatgaacgcc ggtatcggcg agttgatgcg
     1021 tacggcttcc tttaaggata aggcccgtca gcagttgcat atcagccggg aaggatgtga
     1081 aggcgatgta gagaaagaga tttttaatga aggtaataaa catagcgtaa gcgctggttt
     1141 gttgacttac ccgaccttga tggccgccga tattattatc cataaggcgt tgaaggttcc
     1201 tgtaggtaag gatcaagagc agaatatgga aatggctcgt cgtttcgccc gccgtttcaa
     1261 ttctacctat ggagtagatt tcttcccgga accagcttcg ttccatttgg gcaataagtc
     1321 cgtgaaagta ccgggcttgg atggctccgg taagatgggc aagagcgagg gtaacgcgat
     1381 ctacttgata gatgatgaga aaacaatcaa gaagaaggtt atgaaagcgg tttccgatgc
     1441 gggaccaacc gagccgaata gcgtgaagcc cgagccgatc gccaatttat tcacgatgat
     1501 ggaaattgtc tccgagaaag agacctatga tttctttaat gagaaataca acaattgcga
     1561 gatccgttac ggcgatatga aaaagcagtt ggccgaggat atcaataagt tctgcgctcc
     1621 gatccgtgag cgtatctttg atatggccgc caatacggaa tatctggata aggtagcccg
     1681 tatgggtgcg gagaaagctc gtgagagcgc ttctaagact ttaaatgagg tacgccagat
     1741 tatcggtttc cgtccatatt gatgcttatt aattaaaaat aagaaaaagc gtttagggat
     1801 aagtccttaa acgctttctt tttattaaaa ccattataaa gaacctgaaa agcgatttgt
     1861 taaaaagaaa aggttgttac tttgcggtga atagttacag ataacaaacg tatggctgct
     1921 attaccaccc aagaatttga acatcatttc aagagtttat ataagccctt gtgtttgttt
     1981 gcgcttcgtt ataccgatca ggtagacgat gccgaggata tcgtgcaaca ggccttcgcg
     2041 gatgtatggg ataagaaccg ggctggtaat gtgatcggga atctcaaggc ttatttatat
     2101 caagcggtga ggaaccgttc tctttcattt acctcacaac ccgtaaacgc tgaggccacc
     2161 gagcagttac ccgacgtaga agatacctcg gaagaggaag acatcctgcg atcggagcgt
     2221 gacgcccgcc tgtgggatgc tatcgatcgg ttacctcccg aacggaagaa gattttcttg
     2281 ttatccaaac gggatggctt gaaataccaa gagatcgcgg aggaattgaa tttatcggta
     2341 aaaacggttg agaaccagat gagcaaggca ttgaaagctt tgcgagagac cgctatccgt
     2401 gtttatatgt tctttttcgg ataaatttta tagaaaggaa tgggggtttt tcatatttct
     2461 ctgtcttaga gataaaggtt acttgtttat ttcattaaag catggagagt atatgaggaa
     2521 gttggtggta tttgtgatgt tgatgacgtg cgtgatctcg gcccaagcgc aatggaaagt
     2581 gacgccggaa gccggtatga acgtgacaaa gtataaggga gatgccgcta aggtaggctt
     2641 taaggctggg gccgcagtct cttatacatt cggatcgggc tggttctcgc ttcaatccgg
     2701 tttgtattat gtgcgacggg ggaaggggct gtcttcttat agtgagattt atggaactag
     2761 tgagagtcca tatgggggac gggaaggtac gagtatattt ctctatcccg tttccagtga
     2821 ttatttgaat ctgtggggat acggttatgg taatggttac ggctttacgg gcttctatta
     2881 tgatacctat ggaattaagg attttgatgt agaaggtata aggcatcgca gtcagaagga
     2941 gcatcgtgaa tatatccaat taccgatctt ggctcgtttc gattggcagg taagtaagga
     3001 tgttcggtta catttggcgg tcggtcccta tttggcggtt ggcttgggag gaaaagtgac
     3061 gtatgaggaa agtgattatt ctttaaaagg aaagctgccc tataataagg aaatatcata
     3121 taacccgttt aatcccggcc aaggatatgc ggtagcgcct cgttttgact ggggagctac
     3181 catagaggct ggtatagagg tgaaacgggt cgcttttaag gttggctatg atctgggtat
     3241 agataagcaa tacaagggat atgcttataa cataggcctg aactatcata cggctagttt
     3301 taccttggga tacacatttt aaagagaaaa taggatgaaa gcgatggttt gtataaagtg
     3361 ggtatttata ttcgcggtgt tgatgatgat tttctcatct tgcgtatcgt ctaggatctc
     3421 gcccagtatg agtgtgggag ttccattgaa gaaggggcag gccccaaatg tcggattcca
     3481 gtggtatgag actggaagga cttattaaat aaaaggaata gtaatgaata acgagcatgg
     3541 caataaatta gaacaacgtg tccgtttcgt agcgaagcgc tatcgggaag gaagccttga
     3601 cccggataag gcatggcaga agttcgcttc tgagcatgcg attagccgga aggtctcgtt
     3661 tcgccggtat tggatcgggg cggccgctgt cgtgttagtg ctcgtaggtc tagggacatg
     3721 gtttacggta gagagaaacg ccccggattg ggtagcgatt actaccgccc ccggacaaat
     3781 gaaagatgtt taccttccgg atagtacctt ggtcgctttg gccggcgatt catggatccg
     3841 gtatgatgcg aagagatatg ataaagagag gcgtgccgtg gagatgaatg gaaaggcctt
     3901 tttccaagtg acgaggaacg aggcacgccc tttctcagtg aaaacgagcc aaacggaagt
     3961 tacggtgttg ggaacaagtt tccagataga tgagaagcct accgttacgg aagtcaatgt
     4021 agttaccggc aaggtatgtt ttaccgccgg ggaggaaaag gagaatgtga tacttaccgc
     4081 tggaatgtcg gctcagtatt ctatggagaa caaggagata acggtagtga cggaagaaga
     4141 cgtgaacaag ttggcttgga ggacagggca acttcgtttt atggagacac cgctggataa
     4201 ggtgattgag gacttgagtg attattatca agtcaagatt gcgaaccaga caaagaatga
     4261 gggagcgaga ttgaccgcta cttttaataa tctgcccttg gaggatgtat tgcaggttgt
     4321 taaccagaca ttggacgcac gtttggtttc cacttcgaag aaataaaatc agatcatttt
     4381 atgagatcta ttgttgtatg gctgataggg attcttttgc ttcccggttg gatgggacat
     4441 ctatatgcgc agatgcccga acctacgccg acggttacgt tggatatgcg gcaggttccc
     4501 ctgttggata tattgatgga gcttgagaaa caaaccggat tgttcttctc gtacgagtcc
     4561 tctctactga aagagctgcc agaggtttcc ctgtcggtcc gggatgaatc cttgtcgtac
     4621 tgcttgaagc gcttattttc cccattaccg attatctatc gggttacggg gcaatatatc
     4681 atcttaaagc gaaagccccg tcaatatacg atcagcggat tcgtcaggga ttcagcctcg
     4741 tatgagagtt tgttgggggc ctcggttctg gtgaaaagtt cgaggggagg gacgatgtct
     4801 aataattacg gcttttacag cttgatactt ccacccggta aggtccgcct tagggcctcg
     4861 tacgtgggct ttaaggcgat ggagatagag atcgatttgc aaagggatac gatgatcgac
     4921 ttcccgttga ggtcattggc ctcgttaggc gaggtcgtta ttcgggggag ccggcctcgc
     4981 tacgagatat tgagtagccg cacgggggtg atcgacgtac ctgccgagcg ggtgaagtca
     5041 atgcccgctt tgctggggga ggcggatctg gtgaagacct tacagcagtt gccgggcgtg
     5101 gcggtaggca ccgagggaat gaccggcttg tatgtgcgtg ggggcggggc cgatgagaat
     5161 ttgtatctgc tggatggaaa tccggtctat catgtgaacc atttgttggg gtttttctcg
     5221 gcgttcaacc cggatgcgat aaagaatacc cggttttata aagggagctt tccggcggaa
     5281 tacggcggaa ggctctcgtc ggttgtagat gtccgtatga atgacggtaa ccggcaggag
     5341 tatcacggga atatctccgt gggtttgctt tccgcacggg ccaatctgga ggggccgatt
     5401 gttaaggatc gctcctcgtt taatatctcg gtacgccgta cgtggttgga tttgataaca
     5461 gggacggctt tggcgatcgt taataagaac agtgatacca aggaaagttt cggttatcac
     5521 ttttttgata taaacgcgaa ggtgaaccat tctttctcgg aacgtagccg ggcctatttg
     5581 agcttttata tggggcaaga tgcttttcgg cagggaagca aggagaagca tgaggattcg
     5641 gatgatatgt ttctctggcg ttggggaaac ttgatcggct ccgcagggtg gaactacgtg
     5701 ttcgggcaaa agctgtttgg taatctaatg gtgggctaca gccgttttcg ctcgcatatc
     5761 cggcaagagg cgaaggggta tgaaatcgaa ggaaataggg cagaacggca atcaattaag
     5821 cgggatagcc gttataaatc ggagatggag gatctgagcg tacggctgtc agtggattac
     5881 agtccttcaa tgaatcaccg gatacgaatg ggcacggatt acctgtatca taattttcgt
     5941 ccggagaata gccagcaacg gtcttgggtg aacgattcgt tagtaaatcc cgtatatgag
     6001 cttttgtatg attattcctt gataaaaggg catgagttct ctttgtttgc cgaggatgag
     6061 atgcgggtca cggatcgctt gcgggtgaat gccggattgc ggtatacctt gtttcatgta
     6121 gagaatgaga tctatcattc ttttcagcct cgtttgtcgg cacgttattt acttcgtccg
     6181 gatctatcgg cgaagatatc ctacagtaag atgaaccaat atgtccactt attatcgaat
     6241 acctatgtga accagcctac ggatatttgg gtcccggtga cggagcaagt ccctccgatg
     6301 agttctcacc agattactgc cgggctttat tataatctga aacggatgta tgatttctcg
     6361 atcgaggggt attataaacg gttgaataac ttgattgatt ataaggatca ttggccggtt
     6421 gagacacatt tctccggttg ggaagaccgg gtcggtttgg gaaagggtaa gacctatggt
     6481 gtggagttta tggcgcaaaa gacaaatggg aagacaaccg gatggatcgg gtatacgctc
     6541 tcttggtcgg atcggtggtt tccggatggt tccgtgaata aggggcgtca tttcccgttt
     6601 cgcttcgaca accggcataa ggtgaatgtg gtcgtttctc gtaagttatc ccggaaggtg
     6661 gagttaacgg gagcttgggt gttcgcctca ggaaaccata ttagcttgcc ggagtataaa
     6721 tatctgtctc cgatttatca gaaagagaac gggtatgccg gagtagaata cagaccgatg
     6781 aattcaggtt tgagcgctcg taataattat caattgtctc cttatcaccg tttggatctg
     6841 ggcgtgaatt tttatcgata taaaaagaag ggtcggatgg ggatttggaa cataagtata
     6901 tacaatacgt atttgaaacc gaatcccttc atgacggagg ttatggtaaa ccaggatata
     6961 aatcagcgat atcatgtagt gctacaggag acgattttgt tctattgcat gccctcggtt
     7021 tcttatactt ataaattcta gcttatgaaa agatatttac cttgcctgtt tgtgttagga
     7081 ttattgatgg tctcttgcgt tcgggatgtg gagattgatt tggaggatct accggatcgg
     7141 attgtactga acgcatcggt atgtcccgga aaggaggtgt gtgctcatct ctcgaaaaca
     7201 tggtttatca tggatagcgt tcccgatttt gagctatccg acgcaaaagt ccgtgtctat
     7261 gtcaatgatg agtttcaagg tcttatgcgc aatgatgacc tgccggaaga ttctatacat
     7321 tcacgggggc aatatgttct gcccggttgt ttcgtgagac agggggattg tttgcgtata
     7381 gaggccgagg ccgatgggta tgagccggta tccggggaaa ctcgtatccc cggtcgggca
     7441 cggatttatg aggtggatac cttatcctat cgatcttctg cctactatgc cgaatatctg
     7501 cgtttctctg ttaaaatcgg ggttgagacg gattcctatt atcgtttaat cgtggagcag
     7561 atcttggact tccggaaggg ggatagtacc cgtaccgtaa cctctttccg tagcttagga
     7621 ggatatagtt ggtattattc tggttttagc gtggattatg aggatcctgt tttccagtct
     7681 tttggaggta gtcctatcac gagccagatg gatgggcgtt actgtatggg tgtatttaga
     7741 ggggaggatc tggttaatac gaatgctatt aaggtttctg tttttcctgt tgaatactcg
     7801 tatgagagtg ataccctttc tatggacgtt cattacgatg tgcgcctgtt gtctatctcc
     7861 gaggattatt atcgatatat gaagattatg agggggtact ctatcacgat cggcgacgcg
     7921 aatttcgggg cgttgataga gcctgccgat acgtattcga atgtggagaa cggctttggg
     7981 attgtcgccg gatatcaaga ggataaattg cgtatcacga tgccgagaga cacggtgcct
     8041 ccttattgga atccttggga tggataagcc catcccgcgt tgacgacctg tgcttgccgg
     8101 ttcatacatc atgaagcggt aagttcacga ggtatgaaaa aaaggctttt ccttgatagg
     8161 ggtatttccg ggagatcctg tcttatcaat gaactcaata aagtagaatg atgacagagt
     8221 ggatgaataa atggcttatg gccatttttt gctggatgat ttttatgcct gttccagacc
     8281 tcttggccca atcagccaag acgaaggatg atccccggat tacgttacgt atgaaggagg
     8341 tttcgttgcc ggaggtcttg tcagagatcg aaaggcaggc gggcgtgacc ttctcgtatg
     8401 agtcttcttt gttgaaagag cttccgaaga tcagtttcca agtgaaagat gaggcattga
     8461 cggattgttt gacccgcttg ttcgagtcgt atccgatcgt gtataaggtg agtggaaaga
     8521 tcgtgattct gaagcgtaga cagagacagg taacgatcag cggcttcgtg agggaccaag
     8581 cgtcctcgga gtctctgatc ggagcctctg tttatgaggt cgccagccgg aaaggctcgg
     8641 ctacgaatag ctatggtttt ttcagtttga cgcttccgcc ggggaatatc cgcttgcatg
     8701 cttcttacat tggctatgag agctgttcct ttaatttcac ggaattggat agggatacca
     8761 tattaaatat tgagttgcgt ccgaacgctc gtctggagga agtggtagtt accgcttcgg
     8821 agcgggatcg tttgtctgta aataacacct tgatgggaac gatggggttt agccagaaga
     8881 cgatcaaggc gacaccgacc ctgtttggtg agtccgatat tgtgaagacc ttgcaactga
     8941 ctccgggtgt agccagtggg acagagggac tggccggttt atatgttcgt ggcggcgacc
     9001 aagatggaaa tctgtttttg atagacggta atccggttta ccagatcaat catgtcggcg
     9061 ggctattctc cgctttcaat ccggaggcga tccgtaatct ggactttttc aaggcgggtt
     9121 tccctgcgag atatggcggg cgactctcgt ctgtggtaga tgtccatacc aaagagggca
     9181 atatgaaaga gtaccatggt agcgctacga tcgggctgat ctccggtaat ctgagcttgg
     9241 aaggccctat catcaaggat cgcacggctt ttcagatagc gcttagacgc tcgtggctgg
     9301 atgtactctc tgccccagcg atagcgatag caaataaggt tcgaaaagac ggtcataaaa
     9361 taaatcttcg ttacgctttt cacgatttga atttaaagct taatcatcgt ttcagcgatc
     9421 gcagccggat gtttttcagc ttatataacg ggaatgatgt attaaaagga gggggaacgg
     9481 atttctcaac agaagaagag caagtccctt atacggatgg tacccattca tcgctgcgtt
     9541 ggggtaattt gatgggaacc ttgggctgga cttatgtctt caataaccgt ttgttcggac
     9601 gggtttccgg ggtcttttca cggtatcgct cgaatgtacg gagttcaaaa gaatataatt
     9661 atggtgtgga aggagaagat aattatctct cttcttcatc ggaaacgagt agttctacct
     9721 ctatcttgga tatgggcgtc cgttcctctt ttgattacac gccttctacg tcgcatgtga
     9781 ttcgttttgg aggggatttc ttgatgcacc gtttccgccc ggagtataat gaggtgaaag
     9841 cagccggttc cggtatgctg gagttttcga atatagggaa aatatatacg aatgatctgc
     9901 tatgggcccg tgaggcggct gtcttcggag aggatgattg gaatgtctta cctagcttgc
     9961 gtttgaatgc ggggcttcgg tttagcctgt tcaatgtaga gcggaaggct tataccttat
    10021 tggagcctcg cgcttccttg agatggttgc tacgtgacga tcttagcttc aaagcctcat
    10081 acgcccgtat ggggcaatat atccatttat tgggcaacag ttatataaat ttgccgacgg
    10141 atgcgtggat gcctgttacc cgtaagttga aacctttaat cagcgatcaa gtctccgctg
    10201 gtttctatta taatctgatg cgttcttata gtttctcggt agaggggtat tataaatgga
    10261 tgaagaacct gttggattat aaagacggtt attccttctt gcccggtacg gcggcttggg
    10321 aggaaaaaat ggcggttggc aagggacgtt cgtatggcgt ggagttcttg gctcgcaagg
    10381 aaagcggacg tacgaccggt tggataggat atacactttc atggtcggat cggcgtttcg
    10441 atgagatcga taacgggcga cgctttccgg cacgttacga taaccggcat aagctgaata
    10501 tcgtggtttc acataaactg tcggataagg tggaactgac agccgcttgg acgtatactt
    10561 ccggcaatcg catgaccttg tcgttggaga gttacgagca agcgcaggct ggcacgctta
    10621 attcccttga cccatacgga caggataact ggtcgggatc atccggggaa gtggtggatt
    10681 tgtatacacg ccgtaataat taccagatgc cggcttatca tcgtctggat ttgggactta
    10741 atatttaccg tccgaagaag aaggggcgaa tgggcatctg gaatatcagt atttataatg
    10801 tatatagccg gatgaatccg tttatggtct ataaaagtga tagctgggaa cgaacgaata
    10861 atttagtccc gggttcttct tctccctata gcggtaatag aaaaccttgt tttaagttga
    10921 taggtattat gcctatcata ccttctatat catatactta taaattctag gaagatgaaa
    10981 cagataaaga gtatcttgat aaatacgatt tgtatagtaa gcttgtctgg tttgatgtct
    11041 tgtgtcaagg agatcgacct tgaatcctta cggccgaatc ctaccttggt agtgaactgt
    11101 gtcgctataa ccggcgaatc cttaaccgta agtgtctccc gtacttggtt ttttacggat
    11161 gatcatccga acgtgacttt ggataaagcc gaggtgaatt tattcgtgaa tggcgttttt
    11221 aaagagcgta tgagctttca agagggggat gaggcattta acacgaaagg ttatttcaag
    11281 tctgatttta taccggtgaa aggagatcgc atccgtgtgg aagcctctta tccggaatat
    11341 ggggtggcaa gcgctgagac ggtcatgcca gcgcctgctc aggtcttgaa agcgggggta
    11401 acatatgcta cggtagctgg ctcttttggt tctgctcgcc agaatgcgat ttatcaggta
    11461 acgctcaaag ataaccctgc cgaggagaat tattatttac ttcgtatgga agagggcatt
    11521 cctgtttttg atggaatagc taaggaatat acaggagaat ataaatggtt ctcggtgagt
    11581 ccaaactatg cgactgaacc tgtttttggc caatcgttga cagccttgga tcaaatcttt
    11641 ggcaatgact ggatgtatgg gtatgatgga aaggtctttt ctgatgagtt aataaacggg
    11701 caagaatata ccttgcactt aacggatgag tattattatg aaccttatta tggatcatat
    11761 ccgctaaaag tagtcccgga ttcgataggg atggaagatc taaatgagga agatttcctt
    11821 ccgattccac ccaagcacct acgggtacac ctatatgcta tctcggcgga atactatcga
    11881 tatctgaaag ttttgcaaga taaagacaca gattcagttt cgaacctttt gatcgatggc
    11941 ggtctggccg aaccgatccg tgtatttagc aatatagacg gtggtgtcgg tatcctaggc
    12001 agttgccatg taggaatgtt tgagacggaa atagcgtctt cctcacattc caatcttgaa
    12061 gcggcccgat ttgaagacgg gatagactag gaactgtggt tccattttcc gtcgtaccgg
    12121 gttgtattca tagttaacac cggctcccat ccagaaatta tcagtgatct tgaactccat
    12181 tgagccgccc acttgggtat ggtagagaaa agggttgctg agcatatggg ggttgttgta
    12241 ctcgtcggcg taataagcgt attgtcccca gcctttcagt ttcaaccagt cagtaggttg
    12301 atattccact tgtacgtttg cgcccgctgt tattccggga ctagggttga agggactaaa
    12361 gaaacgaccc ccgaatcctc cgccataaag actccaattg ccgctgtgcc aagaaatacc
    12421 cccgttcatg atcgtcatgc ctccgactcc cggccatgta tattgaacac cgttagcgat
    12481 aagatcgaaa ctttcgttta gccgtttcat ataagtctca ttgaaatcca acgccattgg
    12541 cgatacctcc cgaagcatcg gggtatatac gttaaagaac ggctgatagg cggcggaaga
    12601 tatctgcata tccatcggac gctcttgtag ggacgtatgg ggaatatcgg gcgtgaactc
    12661 ccgcaattta atatcgatat cccgtgtccc cgcaggggta aatgtcttat aagaggcttt
    12721 cgggatgttc aactcatacg tcttgttttt aggcaggacg atgattttac cttctttatt
    12781 taaaataaac gaaaagtcag actgtgcctg gattccaacg acacatatcc atgccatgaa
    12841 tataaataat cctcgtctca tacactctcc tcctattttt gatgtgaagg taactttttt
    12901 ttgaataaga tgcaactttt aggataccta tttcatccat ataatagaga gcataagtac
    12961 ttatggatga acaactgtta atcgatggat gtatgcgagg cgaatcatgg gctcgtaagg
    13021 aattgtacga gcaatatgct cctgctatga tgagtgtttg catgcgttac gtgggtgaca
    13081 gggagacggc ccgtgatctt ctgcaggacg ggttcgtgaa gatatttacg aagatccggt
    13141 cgtattccgg ctccggggct ttcggggggt ggatacggcg gatctttgtc actacggctc
    13201 ttgaatatct ccggtcttca gagaacacga ggctaagtgt aggtttggat ggctatgacg
    13261 acagtttgga agatatcaac tactccgtat tggaccgttt atcggcggac gacttgttgg
    13321 cttgcgtggc ccaattgccg tcgggatatc gtacggtctt caacttatat gcgatagagg
    13381 gatatacgca tagcgagatc gccgagatgc tgcatgtaca ggaggcgact tcccgctccc
    13441 agtttatccg ggcgaggaac gctttgcaaa agagtgtaca atctttaata aggcatgaaa
    13501 atgcgggacg ataaggatca taacgaacgg ctggatgatt tcagcggcta tatgcggcag
    13561 cgcttggaag agcaccggtt gccggtagat gccggctgct gggatgaggt ggaggcccgg
    13621 atgaaccgga gagcgagacc acggggttgg ttgtggacgg gaggcttggt cgtcgccgca
    13681 gtgctggcct tggttatttg gctgctacct tccccggaga agatgccatt ggaggaattg
    13741 agcccctttc agaaagagat atcggagaaa gcggaggaaa tgaatattct ttcggagcat
    13801 cccgttttac ctgtagagcc tgtaaagaaa cgtatagcga aagtgctgaa atgggaaaaa
    13861 aaggctaagc tttccgctat tgtcggggaa aaggaaacga ttcgggagga tgagaagtgt
    13921 gagactatcg agattattga gaaggatgcg attgcggcta tcgtagaaga accgtctgtg
    13981 aaggaggatg cgtccgagga ttcgacggac atagtcgtta agcgaggtga ctctacggtt
    14041 cctctaccgg aaggcgaacg gagtccccga cgaaaagcct ctttgaaaaa gaaagccaag
    14101 aagagtaaac ggaacaagtg gttattggcc gccgccgttg gctctagtgg ttatgtagat
    14161 agctttttaa atacggatat gagttatggc gatgcttctt ctccgggaga tatgaataat
    14221 tcggcaggaa gccccgatcc ggataagccg gataaagacg atgatgaaaa ggagagtggt
    14281 aatacgcctc cccaaacggt ctcattccgt aatgccccgg tattacggag ttctaaggtg
    14341 gatgagaact tcttggataa tcgttcgttc gaatcttatc cggacgttag ctactccctt
    14401 ccgatatcat tcggttttac ggtacggaag gatttgagcc ggcgtatagc cgtggaaagt
    14461 ggattgatgt atacgtattt atccactaca ttcaagaggg gaggggattg cccgtcagag
    14521 gtgaaatcgt ctttgcatta tctgggtatt cctttgaatc tggtggttta tgtatggaag
    14581 aatcagcgat ggaatgtcta tctctccgga ggctttatga tggagaaggg tttgcaggcc
    14641 gtgtatagtg gctatatcgc cggaaacgga acgactatct ccaagagcaa aaaggagggc
    14701 atccatggta tgcaatggtc cgtgaatgcc tcggtcggtg ctgcttatcg tttctatggg
    14761 gattggagtc tctatttcga gcctcgcttc tcccattatt tcgactgtga tcaaccggct
    14821 agtattcgta cggacaagcc gttgggattt gggttgagcg caggtatacg atatgctttt
    14881 taatgattaa atctattata attatgtgga aactttttta ttgggcgttt gcctttagcc
    14941 tttgcgtctt aatgggatgc aaggatgatg gagtgagagt ggaggtcgtg cggtatgcta
    15001 tcaacgaacc ggtattcatg tcgatctccg agtttcggaa ttcagtgaag gtgacggatg
    15061 aggtggtgcc aatcaccaag cggggtaaga tctgtttcta taagggttac ctgtatattt
    15121 cttccccaga taagggcatc catatcgtgg ataacaggaa tccggcatct ccccggatag
    15181 cgggctttgt agagttgatc ggtaacgagg atctctcgat caaggatgat aaattgtatg
    15241 cggattcgta tgtggatctg gtctggttcg atatctccga tccggagaga cctgaattgg
    15301 aaggtcgtgt ggagaacgct ttccgttatg cgcttccgac catagagaat ggctatgggt
    15361 tcgattataa tatgtgttat tcggaagaag cgagagcgaa aggtgtcgtg gttggttggg
    15421 agccgaagga acgggaggaa accatttacc attatccgag ttatggcggt gatctgatgg
    15481 cgaacgatgc ggcgccgggt acttccacgc agggcgtgaa cggatctatg gctcgttttt
    15541 ctatttatgg taagtactta tatacggtag aacagaatat catgtgtgtt ttcgacctgt
    15601 ctggagacaa gcctgtcttg acgacaaacg acatttggtt gcaacgtgat gtcgagactc
    15661 ttttcaacta taaagataag atgttcatgg gaactccgac cggcatgttg atctattcgc
    15721 tggaagatcc gttagcgcct aagtatcgtt cttccgtaag tcatgtcttt ggttgtgatc
    15781 cggttgtcgt ggaggatgac ttagcgtatg tgaccgtgca ttccggaaat acttgcgggc
    15841 aaaataccaa tgaactgatg ctcatagatg taagtgatgt ggaccaaccg aacctgctgg
    15901 ttacttatgg catgaaatgt ccgaaaggat taggtatcga taacggtact ttattcctct
    15961 gtgacgaagg gttaaaggtc ttcaatgcga aagatcctat gaccttgctg gctaatcagc
    16021 ttgttcatta tgcaggtatg gagggttacg atgtaatccc ttttaggaat accttgatga
    16081 tgatcgccga tgatggcctt taccaatacg attattccaa tttacaggca atatctcagt
    16141 taagtaaatt gccaatgggc gaatagagtt taatattcct cttcactatt tgctttgtaa
    16201 ggcatttacg ggattacgag gtgccgcttt ataactatgc ctgcttacgg tcagtaacgt
    16261 aaccatcagt acgataccgc cgaatagcag gcttgtttct atggaatacg ttcacgaaaa
    16321 ttcgctactt tttatgtgtt atttatacga gaatgtaaat aaaatgagct tcctactttg
    16381 atgttataat atttattctg atcttgcgga tgttattgtg tttgataaat taaaatctaa
    16441 aactattatt atgaatcttt ttgacaatat gcacggacta aaaggatgca ttcgttgttt
    16501 gacttttaaa aacgtgcttt tagctcattt tttattggct ttttcagtgg caggtagtgt
    16561 ttctgccgag gctttgccta cttcttattt aaatggcatt gaacaacaat cccggaaagt
    16621 tgcaggacgt gttttgcaaa gagttgataa cgagccggtc attggtgcta atattgttgt
    16681 gacaggtaca acaatcggta caattacaga tgtggaggga cgtttctcat tggacaactt
    16741 gccggcaaat gcccgtacgc ttaccgtatc ttttgttggc atgacttcgc aaacgcttcc
    16801 gatcaaatca gagatgatga tacttctgga ggatgattcg gaaacattgg atgaggtgat
    16861 ggtcgtggcc tatggtacgg ctaagaaaag tacgtttact ggatctgcca gtttgctgaa
    16921 gtcagagaag atagaggctc gtcctgttac atcggcaact tcagccttac taggatctac
    16981 gccgggtgtg caagtagcct cagccagtgg tcagcccggt tcagattcgg atatctatat
    17041 tcgcggattg ggctctattt ctgcgacgaa tacccctttg attatactta acggtatgcc
    17101 ctacgatcag agtatcagta gtatcaatcc cagtgatata gagagtatgt ctgttttgaa
    17161 agatgcctca tctgcagctc tgtacggcgc acgaggtggt aatggtgtta tcttgataac
    17221 caccaagacg ggtagtaagg atcgtatgtc ggtgaatgtg aaaatcaacc aaggattcac
    17281 gaatcggcaa agtcaggatt atgaacgatt gggcgtgaat gattatttga aagtatattg
    17341 ggagagcgca cgcaaccagt tgataagtgg tggtgcgtca ccagagcaag cgggaatggc
    17401 agccgctcaa aacttgattt caggaacgct gggcttcaat ccgtttaacg tgccggacga
    17461 tcaggtcgtg gatgcgaacg gtgtgcttaa cccgaacgct acgttcatgt gggcggatga
    17521 taccgattgg gaagacgcta tctagcgcac gggcagccgt acggatatag gcgtgagcgt
    17581 gagcggaggt aataataagt cggattatta tctttccgcc ggttatctga cggaaggtgg
    17641 ttatatcatc ggatcgaagt ttgaccgata taccttgaat acgaatgtta actcgcagat
    17701 cacctcgttc ttgaagattg gcggtacgct ctctgggaat atcagcaagg cggaagggca
    17761 gcagtcgcaa gcttcgggaa ataacaacaa ccctttccga ttcactcgct atatcggacc
    17821 gatctatccg atccatgtac acgatcctcg taccaaagaa tatgtgctgg atgccaatgg
    17881 taataaagtg tacgacttcg gtcaggccta tacgatcgag gagggtgtgg aagcgccttc
    17941 gcgtgcgtat atctctggta ataacccggc tattgagttg caaaatatca gcaacggata
    18001 caagcggaat caattgaacg caaaattgta tgcggagatc cgtttcttga atgatttcaa
    18061 gtttacggtg aacggagccg tgggaacaag ctctcgttta gggcattcgg ccagtatcta
    18121 ttatccggag aagactgagg tggggtcaag cacgaagacc gtttcgtttg agacaacttg
    18181 gacgttcaac caattgctct cctatacaaa gaatttcggc aatcaccatg tcgatgtctt
    18241 attaggacat gagagttatg attatgagta caattacctg aaaggctcca tgcaaaacca
    18301 gaccatccat aatggcaact ttgagttcag caattattcg gtgccggacg agcaagactc
    18361 ttatacgaat acctacaaga cggagggatt ccttgcccgt gcgaactatg actataacag
    18421 ccgttatttc ctttctgcat ccgtgcgccg cgacggatcc tcccgctttt acaaggattc
    18481 ccgttggggt acattcttct cggtaggagc tggttggcgt attgacgagg agcgtttcat
    18541 ggaagatctt gatttcatcg atttgctgaa gttgcgtgtc gcttacggtg aggtgggtaa
    18601 tgatgccatc ggtagctact atgcgtggca agcggcttac gagcaggcca tgaacggatt
    18661 ggaggccggt tatatccagc aacgtgtcgt tcgtaataag gatttgcaat gggaggtgtc
    18721 tcgcaatggc gatgtggcgt tagagtttga gttgtttaaa agccgtttgt cgggtagtgt
    18781 agagtatttc gatcgccgtt ccagcaactt attgttctcg atcccgcaag caccggatac
    18841 gggtactacc agcgcatata agaatgcagg tacgatgtac aatcgaggtg tggaagttga
    18901 tttgaacgga agaatcatcc agacgaagga ttggacgtgg tctgtgggaa ttaacgctac
    18961 atggttgaaa aatcggatta cctctttgcc ggtagaacct tataacagcg gagtacatcg
    19021 ggtggaagag ggacattcgc gctatgagtt ttatcttcgc cagtgggcgg gagtagatcc
    19081 tgctaccgga aactctatct atgtgccgga tccggaactg acggtggagt ctgtcgacct
    19141 ggtagaggtg gatggaaaaa catatacgac taacgtgaat gaggccattt atgattgggc
    19201 cggagaatct acaccgaagg tatcgggagg tcttaatacg aacgtatctt ggaagaatct
    19261 ttctttaagc ctgttgttta acttccagct aggtggcaag atgtatgatg taggatattc
    19321 tgatttgatg acacagcctt caggatccgc atccttgact tccaacaagc atgtggatat
    19381 cttgaatcgt tggcagaaac cgggcgatgt cacgaatgtg cctcgcatcg aggatttcgc
    19441 agatacgaat atgaatgcgg gaacttctac tcgttggttg atcagctcga atatgttgga
    19501 gttggcttcc gctactttga gctatgatct gccgaagcaa tggctggaga aggtttccat
    19561 gcaaggactc cgggtatatg cgtcaggaga gaatctattc ttgctgacga aacgaaaagg
    19621 tattttccct cgttcaaaca tattctcagg atatagtggt aatgcggatg tttatttgcc
    19681 tgcgagagta tttacttttg gtttgaatct tactttttaa atcatgttca atatgaaaaa
    19741 tatatatata gtagtgttgc tatctcttgt ggtattattc aatggctgca aggaggattt
    19801 tttggagaca acttccacac aaacggtgga tgagcaagca gtgttcaatg atacccaatc
    19861 ggctatgttg gctgtaaatg gcttgcataa attgatgtgg acgggtgatc tgtctagttc
    19921 ggctttttat ggcggttacg atatgttgat gatttggtat gaggtgatgg gggatgattt
    19981 ggtatatacg tacagcaatg cgcagttcca aaagcaggct caatggtcga gccatcggaa
    20041 tgcgacgatc ggtagcgcga cccattttta tcgcttgttg caatatttta tctctaacag
    20101 tagtatgatt atcgataata tcgatgctgc ggaaggtttg gagagcgaga ggaattatat
    20161 caaggggcaa gcccattttt accgggcttt cgcctatttc acgatggtac agatgtatgg
    20221 cggccgttat aaggcagagg gcgataacac gcaattgggt gtggtaattc gtaacgataa
    20281 ctcaacggag ccgagagcga gagcttctgt agaggaggtg tatacgcaga tcaatgagga
    20341 tatcgacttg gcgatccaat tattgggtgc tacggaggag aaacggacta ataagtcgca
    20401 tattgatttg cacgtggctc gcggtttgaa ggctcgtatc ttattgacgc aaggtaaatg
    20461 gttggaagcg gctgaaatgg ctaaattggt cgttgatcta tcaggagcca aattgcaaga
    20521 tgatacctat acgacattga atgatcgttt tagcgatcaa tcaaatacag aatggttgtg
    20581 gggatcgaat cctttgttgc agcaagctcc gaacttgact cacttccatg gatatatgtc
    20641 gaatgagatc atttcgtata atggcaatac ccctcgtgcg atttataata agttatacga
    20701 caagatcagt gataccgatg tgcgtaaagg aatttggttt ccgagggcga ccgatcccaa
    20761 tactcttccg cgaccgatcc gggcggagtg taacagtaaa gcgtatgcta attatatggc
    20821 caataagttt atcgtatcgg atcctacgac gaaaggtggc cgggatgttc ctttcatgcg
    20881 cttgccggag atgatgttga tcatggcgga gggatatgca cgtgctgggg agccaggcaa
    20941 agcggctcag gctctttatc cgctggcaag tcatcgggat ccggagtata cattgtctac
    21001 gaaaacgggc gaaaacttga tagaagaggt gatgactcaa cgtcgcatag agctttgggg
    21061 ggaaggtttc cgttggttcg acttgaaacg tttgaatatg gatttggacc gtggaccggc
    21121 tcctcgtcct gaggttttcc cgaatggttt gattgaatat tggaacaaag acgcaatgcc
    21181 taaagtggtg gatccagaag cttctaatta caatatgtat ggagatggaa cggtgacggg
    21241 taacgggaac agatatcgtc cggccggaca tagggattgg caatgggcta ttcctgataa
    21301 ggagactcaa ctgaatccgc tttgcgaacc gaatccataa agtaaataaa tagttatgag
    21361 aagatttttt ttaatgtgcc tgttgccaat cttcttggcg acaggtgttt ttgctcaacc
    21421 acaagcggat gagtatccgt atgatttaac gtatttcttg ccggaaggtt ctcaggttta
    21481 tgaccctcag gttcctaccc cggaaaaaat cttgggattc cagcttggag aacaacatgc
    21541 cggatgggat caagtagtgg aatatatgag aacattggcg cgatgcagcg accgtgtcac
    21601 gattagggag acggggcgta cctatcagca ccgtcctttt atagaggtcg tgtttacttc
    21661 ggccgagaac caaaagaata tagatcgact gaaggaggag cacttaaagt tgagcgacgt
    21721 ggcgaaatcg agaagcgtag tgatagacga catgcctgtg atcgtaagct tgatttatag
    21781 cattcatgga aatgaggcat cgggtgtgaa cgcttcgttg gctgttgcct atcatttggc
    21841 ggcggcacaa gggcctgaga tcgaggaatt actagaccaa gagattgtcg tgatgactcc
    21901 cggagccaat ccggatggaa tcaatcggtt tgcgtcgtgg gtgaattcct ctagaagttt
    21961 cacgaatgtt agcgatataa aatcacgtga gtttaccgag ccttggcctt ccagtcgtac
    22021 gaaccattat tggatcgatt gtaatcgcga cttgcttatg gcacaacatc ccgaggggat
    22081 caatggctta aatggatatt ttgaatggtt gcccaatgtg gtcgtggatc aacatgagca
    22141 aggggcgtta cgtccttatt atttcagtcc gggacatcct aagcgtaccc atccgtttac
    22201 tccccagctt aatcaagact tgacagccga gatttcttct tatacggcaa aggcactcga
    22261 tcggattggg acgacttatt attcgaagga gggttatgat gacttctatt acggaaaagg
    22321 ggctgcttat ggagatgcgc atggatccgt ttgcctgcta tatgagcaag gttccacgcg
    22381 cggacatttg cgtaataccc cgagcgggga atggaccttt ggctggacga tccggaatca
    22441 ggcattagcc tcttgcgcta cgctggaagc ggccaaggcg atgcgtaccc gtttgctggc
    22501 ttatcagaag gaatattatg aacgtacggc ttctgaggcg cggaaggagg cggtacaggg
    22561 ctatgtgttc gatacacgcg gatctaagtc tgtcgctttt catttcttgg agaatatggc
    22621 ccgtcatcat atcgaggtct atcagttggc gaaggactat caagccgcag gtaacaagga
    22681 gttccaaaaa ggttcagcct atgtcattcc ggtggcgcaa aaatacagta cgatggttaa
    22741 ggtgcttatg gaggattgtt tagaatatac ggatagtact ttctatgata tctctacatg
    22801 gacgttcccg catgcgttta acttggagtg tgctccggtg aagagtgtcg ccggattgat
    22861 gggtgatcgg attgagcgaa atgattttcc gcaaggacgg ctcatcggcg gggaaagccg
    22921 ggtggggtat gtgtttgaga accgggagtt ttatgcacct aaggtagtct atgagttgca
    22981 gcgtaagggg attcgggtca gtgcgaccaa ccgtccgttc caatttaaga acgaagaggg
    23041 agaatggacg atgggctatg gtacctacca ggtattgacg cataatcagc cgcttccttc
    23101 ggatgtgctc tatgcgacat tggatgagtt ggcgaaaaat acgggagtgg atatctattc
    23161 ggccaacacg ggattgatgg ctgatgtgga ttttggcagc ccggctttta aaccattgga
    23221 gcagccgaaa gtggttatgt tggtaggacg tggcgtaagt atcccggaat cgggtgagat
    23281 ttggttcttg ttggataagc gttttcagat gcgtccggta ttgatagaga acccgtcttt
    23341 gacaggcaag gacttgaagg cttacaatgt tatcattttg gctaatggtg ttccaaatct
    23401 aactaagggt accgagactg ccttgaagga gtgggttgct gccggaggag tgttgatcgc
    23461 taccggaaag gctagcgcat gggctggtaa acaagggctt atctctttaa agacaaagga
    23521 aacattgctt gaaaaggcgg acagcttatc ggtttatcgt tcttttgcgg ataaggcgga
    23581 agcaaaagcc ggaaagttga tcaaaggggt aattctgaac tgtcatttgg ataagacgca
    23641 tccgctagct tggggacttg atcaagatga gattgctgtt ataaaaacga atgatatcat
    23701 tttccagaaa gatagggatc catatgtttc gcctttatat tataccaaga agcctttgtt
    23761 gtcgggattc ttgtcggcgg ataatgcgaa cctattgaga gaggagcctg ctataatggt
    23821 gaaaccttat agaagcggta aggtgattgt ttttgctgat gatatgaatt tccgttctta
    23881 cttctttgga actagtaagt tgttcatgaa tgcgttgttt tataacaaat gtatgtagtt
    23941 gtcggatgag tacgcaacga aatatattgt gtctcatggc tcttgtttta tcaggagcca
    24001 tggaatttgc caatgcttgc acgtcggcta tcatttctgg caaggtaaca cctgacggac
    24061 gtccgattat gtggaaaaat cgcgatgcgg aaaacttgaa gaattgtgtg cggtcccatt
    24121 tatctcgctc gttccataat cctttgatgg gtatcgactt gaaagatgga aaacataata
    24181 agccagagac ttccagttgg tttgcggagc aggattttat cgctcgtaga agtacctctt
    24241 gcgctgtggc tattcaaggt gtacggccgg acgaggatgc ttcgttcact acgatgtgga
    24301 cggttatcgg ttacccaccg gttactcctg cggttccggt ttggttgaaa ggcgccgata
    24361 agaagttgcc caaggcgtta actgtcgatc aaaataaaca tgctccgtta tgtgacgcgt
    24421 cgaacatgct tcgggataag atttacagtt atcatcgggg gacgaatacg gaaagttatt
    24481 tccattggga attacttttc aatctaagcg gcaatgggta tatgcagcaa accgagcgat
    24541 tggaggagga gttattcgaa cgtttttatt cctccatcga aacgtggcga tcaaggtcgg
    24601 taattcccga ggaattggtt ttcaatttgt atgatgattg tgatgcattc cttgatgaga
    24661 agacactgag gtgagtatcc aaaatattcc ttttcgctat tcgctttgta aggcatttac
    24721 gggattgcgg gatgccgcct tataactatg cctgcttacg gtcagtagcg taaccatcaa
    24781 tacgataccg ccggacagca ggcatgttcc tatggatatg tccacccgat atacgaaatt
    24841 ctccagccaa caactcagcg aataccacgt gataggaacg gcaatcgcga aagcgatccc
    24901 tacccagccg ataaaccgac gatttaatag atacaagatc tccccggccg tagccccgtt
    24961 taccttacgg ataccgattt ctttcgtacg ctgctggatg gcatagagag ccatgccgaa
    25021 taatccgaag gcggttagca ggaggctgat gatcgagtac atgatgagca aatgtgccag
    25081 ttcgatcgtt tttcggttag ataacataaa ttcctcgtat atatcttggt attcgaaagg
    25141 tacgttggga ttgatctttt cccatgtttg ttgcagtaac gttagagcct cggctctatg
    25201 ctcctttttc agtcggactt ggacgaggtt atagggggga gtatgcgtta ggtaggtcaa
    25261 gctagggtaa acctcttgtc gtaaggttcc tgtatataga ttctccacga tccctgctat
    25321 aatcgctatc ggttctccct ccttttccat cttcccgaat tcagtgtcgt aaaggcggac
    25381 aggcttaccc acgggattct cgcctttggg cacgagcaaa cgtgcgtatt gttcgttaat
    25441 atagacgggt gtgctgtatt gttttagagc ctctcgctct gagagccctt gaagaatgtt
    25501 tatcttcata acctttagga aagtactatc accttcgtat tggcctagcg tataatttag
    25561 ttcgtttccg ttttcgtctt tcaagaccat tgtccgcaag ttgaactgta tgatcccgct
    25621 tctcgaaagg cacatctctt ctatggaagg ataacgccgg atctcttcag agaaggtctg
    25681 tatatggttc ccactccagt cggctatttc gatgaggtcc cggtaacgtt caccgtttgt
    25741 ctgagtgagc gttagttgct gccgtacggt tagcgtggcg aataccagag ctattgagat
    25801 ggcgaattgt aagatggaga gcccgcttat gattgtccgc ttccgggtac cggtggtgaa
    25861 tgatttatac tcggaatggg aaagggagtt gatcttatgg ctcatatata atgaggggat
    25921 aatggataga gctaggatga gtgccacgat cacaggtaag acctgtccac taaagaaaaa
    25981 tcccaaggag atacgtccgg aaacgatctg gttgaaagcc ggcaggaaat ctagtgtaag
    26041 taacaaggat aaaaagaaag cgatcagcac ggtaaggaaa gtatccaaga atagctggcg
    26101 atggatttgc ccagccgatg ctcccatcac cttctgggtg tagatcatcc ttacttgttg
    26161 caaaatgcgg gagaaactta ggttggcata attgaaacag gcgatcacga ggattaggat
    26221 ggctgagaac aaaccaacgt acagtaagtc tttctggttt cggtggatat aggggatgta
    26281 ttcttgtgta taggtttgct cttggaaata actctcttgg agggtataga aataatactg
    26341 tccggttccg ttgaaagtag gtaccttatc atcctttagt ttttgagtga acgtatcaat
    26401 gttgaagaga tcgtttacca gtaataaggt agggccgcca ttgaattggg aggtagtacc
    26461 tgccaatgcg ttgaacttca agaatgattg agggtactct ttgataacgg cggcgacctc
    26521 gtaggtaatc gtctcgttct cataagcgta ctttgccgaa aaggttttac cgataggatc
    26581 ctcgttcccg aagaatatct tcgcttggta ttcggtcaac gcaattgcgt ttggttgggt
    26641 taatgccttg tttatatctc ctgccactac cttgtaaggg aaaaagcgag gaaaggaggg
    26701 atctgctctg acgatcgaga ttgggttgaa gcgcttttct tctatcgtga tggaggcggc
    26761 attgtctatg ttcagtcgta aataatcctc aacttcaggg tattggtctt ttagctgcac
    26821 agggatcttc cctttaataa aagatacttt ctctccggag gtcaagggag agtcttgtgc
    26881 catatagatg atatgcgact tattgggatt atgggcttct atcctagatt cataaatgac
    26941 gtatgagatc agtaggttgg tacaagtgat gcctgccgcc agactcaata aggaaatgac
    27001 ggcgaacgtc ttgtttcgcc accagctacg gaatataagt tttagagata tggattccat
    27061 ggttttatct gtttgttggt tcaaagctat ccggttgcgt ggaatatggc aaataaaatc
    27121 ggaggaaacg ttcgtaaagg actggatttg tctaaatatt ggacactgag agccgggaaa
    27181 agatcgtatc tttgcgtgcg aaaaaagagg aggcttcatg cgtaacgcga agattatagt
    27241 cgtagatgac aatgaggcgg tattgagaag tctgcggacg atcctgtccc atgagtttaa
    27301 gacgatcgtt accgtatcat ctcctgttct attgcctgcc cttttacgga atggagatgt
    27361 agatatggtt ttactggata tgaacttcgg cgctggaaag caaagcggtg gggaagggct
    27421 tttctggttg gatcgtattt tggagcttaa gaatcctccg gccgttatct tgataaccgc
    27481 ttttggggat atcgagttgg ctgtatcttc ccttaaaagg ggagcctcgg actttatcgt
    27541 gaaaccttgg gataacgaga aacttattca aacccttgtc catgtgtggg aacaccgtat
    27601 ggaatcaaat acagataagg cttcatctgt ggccgaatct cttattaatg cattgctaaa
    27661 gaaatatacg gaggcttatg cgaaaccatt gcctcgtctg acagcggagg cggtcgataa
    27721 gttatccgat atggccgggc ggggtgattt ggccttgttg cagcaaatcg tcgaacgtac
    27781 ggtcttactt gtggataaat gccgtttgga tgccgatgat ttctatgtgg aggagctttc
    27841 ggaagtctcc catccttgta cgttggagga tatggaacgg cagtttatcg ccgaggtatt
    27901 gaaagaaaag aaagggaacc tgacgcttgc ggctcaacaa ttggatatta gccgccagac
    27961 cctttataat aagatgcgga aatacggatt gtagattata aggagagtag ctatggttaa
    28021 ccggagttta tacttgaaga ttataggaat cgtctccttg atcgtgtttc tcgtgttact
    28081 tgggtccgta ttgttgataa ccggtacctc ttacttctta tcctttgtat gtctgtgtat
    28141 tatcctgttg ataactctgt tactaatccg gtggatgaac ggtataaacc gtaagatagc
    28201 taccttcttt gagtcggttc gtaatgggga tacagctttg cggtacccaa ataaaacgaa
    28261 tgatcctttt gtaaaggatt tgtatacgga aatgaaccgg attatcctcc tattcagtca
    28321 aaaccagagt gagatggaag agaagcgttt atattacgag agtatcttgc gggtactgac
    28381 gcatgagatt cgtaattcga ttacgccaat ccgttccttg tctgctgacc tattgaaata
    28441 ttccgataca tatactccga agcaattacg ggaaggtttg gaggttattc atgggcaagc
    28501 gcaaaattta tccgccttct tggattccta ccatcgtctg acgcatctcc cggagccgga
    28561 aagaaccgag gtgcctataa cctctttatt tcagaagatg gaacggttgt tgtgtgccga
    28621 gccgggtagc gaccgtatcc gtttctcctc tgcggaagct ttaacggtac gtgtggatca
    28681 aaacttgatc gtgttggctc tgattaattt gatccgtaac gcattacagg cgatagaggg
    28741 gcaagcggat ggtatcgtct ccgtagaagc cttgaagaca gatggtaggg tatatataac
    28801 tataacagac aatggccccg gtatttctcc tgaactattg tctgctatct ttacgccttt
    28861 cttctctacg aagtccggtg gtagcggcat cggcctcagt atctcccacc gcataatgcg
    28921 cttgcatggc ggcgatttaa ccgttgattc cttacccggt gtccgtaccg agtttcgtat
    28981 gaagctgtaa ttgtctgatc aataccccaa ctcaaacggt tgctctacgg caggtacgcc
    29041 ctcggacatc catttaggca tcttctggtt cttcaggtaa tggttgaaga attggaacat
    29101 gcggcgttgg aaatcgatgc ggtttgccat atgcatcggc caatgcggtt cacctgtata
    29161 attcagtaac cagcaaggtt tacctaaccg tttcatggca acgaaatact cgataccttg
    29221 gtaccaaggc acatgaccat cggcatcgtt gtgcatgatc aatattgggg tctgcacctt
    29281 atccatcgtg aacaacggcg agttttccag ataacgaagt ggagaactcc atggcgtagc
    29341 tcctaaacgg ctttgtgtat gctcgtattg gaaagagcgg gccatgccgg aaccccaacg
    29401 gataccgcca taagcgctaa acatatttac gacaggcgcc ccagactcga tagcggagaa
    29461 taaattcgtg cgagtcgcta aataagctac ttggtaacct ccccagctat gtccttgcgc
    29521 accgatccct ttttcgttga tatatccttt ggcgatcatc atggtgatac ccggcatcaa
    29581 gcagttatag cagctttctc ccggataacc atctacatag cgaatgtccg ggttgaagat
    29641 gacatattcg ttgctattgt ataagtgata atcgatcgta gaacgatgcg gttccggcat
    29701 acggtaatta tataaagtct ccgaattccg ctcgtagaag tttaccatca tcgggtactt
    29761 cttgttcgga tcaaaattcg ccggcttata aacgacacct tccagtggac ggccgtccaa
    29821 ggaaatccat gataccaact cggcggtacc ccagataaaa ccttcctgct gtttgtctcc
    29881 atgcgtcaat tgcacggatt tcttgaacgc caaggtcgaa tagtggatat ccgggtattg
    29941 ctggaaggtt tccatcgtat agatcacgtc atccgtattc ttcgccttgt tgatagatcg
    30001 cagcatataa ttgcccgcca gcaaagtctt cggggcggca ggagcggaga ggcgtgcgtt
    30061 gtagaatccg tatccttttg tggcctcgtt gaatcctttt aataattgcg gtttgccgag
    30121 gtcgataaag cgagcctctt tatccagttg ttccaagcgg taggaaagtt tctccttcct
    30181 tccgttcacg gtcaggttga tcggtggggt ggccgcggtc ggatcgaatt tccagatgtc
    30241 gtaacgatca tagatcaaga gattttgatc attcgcggtc cagccggcgg ctccatgcgc
    30301 ataaggatga ttaggaacgt cgttctcctc gtcccaagct gggaagcttt ccggagtggt
    30361 taggcgatat tgcttgcctt ccgccaaggc gatcgtgtac cagcagctat ccgtctcgcc
    30421 ataccaatac gcatatttac cttgtgggga gaggcggaaa cggccataat ccgcttgggc
    30481 gatttgcttg cgctccccgt tatccaacga tacggtataa tagtcgctgc gtgtgcgggc
    30541 ctcccacatg gaagacaaag aatagggacg ggaagtggaa aggagcgcca agggtgcgtc
    30601 accctcatta cccaattgga tattcggtaa ttcctcattc gccaattgga agatagagcc
    30661 gttgcccaga ttataaaccg cttgatagcc tttctttaag tctttttcct tgttgtaatt
    30721 ctgtacggta tattgtacgg gctcatccca actccaaacc tgtacgttcg gacgattctc
    30781 ggctagttgg gtcgtgtctt tttgcctcgg ctccggtgag gtaccgaaga acagacggga
    30841 agcggatttc gagaattgaa gcatcccgtt ctcattgatt acccattcag cggggaaagc
    30901 cctgtttcca cgggtggcga tttcttttgc gggagcgtta tgttcggata gccataagct
    30961 taacgctttg taagaagaat ctttgtcggc gcaatataag aaagctaacc gttccccttt
    31021 ctcgtcgaac gtggtttgtt tgaatacgcc ttttcccttt ttgatgagcg ccggacttcc
    31081 tttctccggg ttcaaggtga atatacctgc ttctccttcc gccgcgctcg tgtaatatag
    31141 cataccgctt ttcttggcga attggaaatc cgttacggtc gggaactgga aggtcttgct
    31201 tccatccagc gaacggacgt acaaagtgga gtccttccgg cctctttgat aagcgatcca
    31261 atccgcctcg tccgctaatt tgaaggtttt gagggagtct atcgtctcct ttttaccggc
    31321 gacggaatag attaccaagg tgttcatcgg catcttgtcc tctttcgtct tcaatacttt
    31381 cagggaatct accgtagact ttccgggtgt ttgcgtgaca accagataac ccgaggaagc
    31441 ggagaacgcg aacttatcgg ccggagaaaa agtggcggtc tcttgccctt gggccgcata
    31501 caaataaacg gtagcgtcac cttcccaagg ttccatcttg caagctaccc attttccgtt
    31561 gtccgagatc tcccggtccg tgattcgttg ccaagtgact aggtcatcga ttgtcaagct
    31621 tttagaggcg ttttgtgcga aggccgggga aagacttccc agacatgcta caaaagccaa
    31681 gtactttaag tgtctcatca tggttatgta ttgattttaa aacaaagata atggctttat
    31741 cagaatcttt gttgcttttg accggaattt gcttctggaa aaacacgtac gtgtttccga
    31801 gaaaacatgt acgtgttttt tgtaaaagtc gtatgtgttt tctggacaag gtaatggcgt
    31861 ttttaatgta ttgattatca gtgttctttt tgagcgttct aatgatcgca gttataagcg
    31921 gcttacaatg ggcattataa aggtgttaca ttgcctattg taaagacctt ataatgggca
    31981 ttatgatgat aggaaattcc tttggtcaac ggtaggaaaa aaggtttgta agtggttagt
    32041 tattcacttc ccaagccgta agttatccac taggtatagc cgttagttat tcacttccga
    32101 ggcccaaaac gggggagttt atattgaata tgttatttat tgcaaggaga tattttagta
    32161 cgctattata atgtacacat gtacattata ttatatatat gaaaatgatt gttgaaaacg
    32221 atcgttataa ttagtcattt gcaaaggtac gcgtttcttt gacttctgca acccttccga
    32281 gctatttttt tgttccctta ttcgctttct tatcaatagg ataggctatc ctttacgaaa
    32341 caagctcttc cttccacaaa ctcccctttg tacctctcga aaaacgcaag atctaaacga
    32401 tcgtttagac tagtcgtttt cgtaaagccg agattggcta aaagggttga tggatatata
    32461 attaacacta ttattaatat taaattttcg atttatgaac aagagaattt ctactttgtt
    32521 tgcgtcgttc ttgcttatgg cgggggcggt gttcgctgct ggagaaacta cacctgcgaa
    32581 aacctatgaa gcacttggta aagtgacgaa tggggaaaag gtgtatctgg gagctgatcc
    32641 taatgaggat actaaagttg ttacaagctt tttaaaatca gaggaagtaa agaatgtagg
    32701 ttacggtttc actacggttg acgaagctgg tgcggaagtg tttacggtaa gtggtaagaa
    32761 gacggaaaat ggtacggact attttcaact gttgaatgcc gcgggtaagg tgatatatgg
    32821 tacgacaagt ggtgacgttg tgggcactcc tgatgcggat gcggtaaaga agggctattg
    32881 ctggtttacg tttgccgaag gtgtgattaa gcttggaaac aagcctttgg catacgatat
    32941 gtcctcctct tccaaagtcg ctaaaatgct taaagcttct aaagaaacga cagtggacga
    33001 cttaaacaag aacctttccg gtaaaggatt ctccttcaaa ttcccgaaag ccgcttcaga
    33061 gccggacgtg aatccgtttg gggagcagat gttcgctatc gacgctgcta cggttaatga
    33121 gcaattggaa ttaggtgtgg aatcggtttc cggtgtatgt ttcgtagtcg ccaacgatgc
    33181 cggtttgaag ctggctaaaa gtgatggcaa aactaaggat aacttgaaag ccgctacttt
    33241 catcgtattg aatccgaacg ctattttcgg tatcactagc ttggatgcta ctcaaggtga
    33301 gggcttcggc ttcactaccg taaaaggcga gaagttgaac tcaaccaatg ttaagaaaga
    33361 tggtaagatc gctttcgtga atgctatcta tagtgtttca gaaaaggatt tggctaataa
    33421 aggtgggcag tatacggtcc agatgaaggg tgttaaggtt acgaaggata cggatgagaa
    33481 ccatggttca aatctgaatg tttacgtcgg cgcttactcc ttgaccgctg gtggcttgaa
    33541 gacctatatc actactaaaa aagatgaagc taagcttact ttggctcaaa caacgggtga
    33601 tacttgggca aaagcttctg atttgttgaa gactgacggt gccgctatct ataatatcta
    33661 ttttacgggt acgcagcctg aatccggtaa ggagaatgaa tctttatatg gcaaatattt
    33721 ggtttctaag tatgcggcta aggctgacgt ggcaagaacg aattcttatt ctttcgttga
    33781 agaggctgtc gctccgaaag acgtagactt gaaggctccg tccgctcaat gggttgttat
    33841 cgcgatgccg ggtatgggta gtgttacgtt caagaatctt gagacaagcg agactttcaa
    33901 ggcaaacttg tacaaaacag ataaggctgg tatctatcaa gccgtaagta ctacggttgg
    33961 tgaattaacc gcggagaata tcaaattggt agccgtaagc ggtaacgagg gcttcttgaa
    34021 cttgacagac gctcaattga aacaaaaggc tcagttggta ttcaatggta aatcagccgt
    34081 ggctgttgat aaactgtaca tgtattacaa tgacgatgct aagaaaaagc aatttgagcc
    34141 gattagtgat gtcgctaaga gctactcttg ggctttcgag aaggctgagt ccgtgaagaa
    34201 caatttcaag tatatctatt tgaaggatga tgccgttgcg gagaaagagg ctgataatta
    34261 taaccaagta gtgaaagctg gcgctaagag attatacgta gatgtaactg aagcttcttt
    34321 ctcggaagat ttggtaggtg cggataaatc ttatacgaat gtaaccgtag atttctatca
    34381 attgggcatc agcttggagg ctaccccgag acacgctaca ttggacggtg atgaaggctc
    34441 aatctccttg aaagagaaca aaaatggtat cttggaaggt gtcattggcg cggagggctt
    34501 gactttctgg ttggatacgg cagacagcaa ggctgagatc ccttctttct atatctctaa
    34561 gggcatcgct accgaagaac ctgttactaa agcggaagaa cctgccgcag ttaccagaaa
    34621 cttcttgtat tatgctaagg actctatgta tttctggaac gaaagcaagg ctaaatttga
    34681 cgtaaacgct aactatgcgt tggaaggctc ttattctaat gatcctacgg aggaaacgga
    34741 tgttaaggct atcttccgcc cggcagtttt ggcaggtgtg gatacgatca atacgaccgt
    34801 gaacggtaag gctgtggtag tggctaaaga gactaaggaa aatgtttgct cagcaggcat
    34861 cgataacttc aagttctata tcacgaaaat agagggtggt tattcagtta cgccggtagg
    34921 tgccgctact acttacttgt atgcgttgaa cggtaaatta ggctttacta ctaatgcttc
    34981 taaagcgttg ccgctaacag taggcgaggg taatcctaca tctaacgagt ctatcgataa
    35041 ttccgtatct tcttctatcg tagtaacagg caacgccggt tatgtaacga tccaaggcgc
    35101 tcaaggcgag acggcttatg tccgtaactt gttgggtatg ccgttggcag agacggttat
    35161 cacttctgat gatgcgacga tcgctgttcc cgctggtatc gttctcgtga cggttggcga
    35221 ggagaccgta aaggttgtcg ttaaataaga catgtaaagg aataatgaaa taagataatc
    35281 atgttcccgt gagggcctcg gtccaagtac cccgtgatgg gcgaacaggc gggagcgatt
    35341 aatattaata ctaaagtaat aaattaaagt tcatccgtaa gtacctccgt gaggatggag
    35401 agcggataaa gaattagccc cggtcgtttg tttgatcggg gcttactttt ggaggttacc
    35461 ggctttgttt gtccatgaag ttaatttatc agggtattag agttggttta tttctactta
    35521 ctgctttttc ttttgctatt gttgtttggt gtcagagcta tgttgtagga agaaccttat
    35581 aaaggcgcgt tgatcctgtt cgtttttaat ggtaagttcc gttttttcct ttttgtgctg
    35641 tagatagtat ttatatcctt tcaatagcac tatgaacaaa actgcaagga gtaaaaagcg
    35701 gagaatatat tcaaagataa tcctgattta tcctttaaat actcgatctt gtcatcgatg
    35761 aaccctgcgt taaagaagta tctttcgata cttatatgtt gctggtaagt atcattgttg
    35821 agatcgtcat cgaggaaata tagtgtttgg atcatttctt tgtaagcttt tccttccgtg
    35881 tgcatttcta tggctcggct atagcgtttt tcaataagtc gaaatcttgg tatatttatt
    35941 gggccgaaat gaattatccc atctaatatc ttctccgcta ttttctcgtt tagcaatacc
    36001 ttgaatctct gattcgctac attttggctt aatgtactta tttgtttata aggccccatc
    36061 agcgtacaag atcgcacaaa tcagcatgcg gtaaatttta ctttttcctg ttctttataa
    36121 aatgccatga taatgaaagc aataccaaaa acactgttct cagccgtaat aatatgccaa
    36181 atatacttga atgtcgttac ggtatttata tctaattccc cggcatacag ggcaggaatt
    36241 aatgcccgtt gtccgtttag ctcatgcgtt atcgaaaaca ggagagctaa gaatccagca
    36301 acgagataat agtaatttat ctttttcatt ttatttttta tttgaaaggg gaagactatt
    36361 gttttacgat aatcttccct ctttgagtta attagatctt cttcccgata taaaacacat
    36421 aaccatagaa ctctttgtat ttgtcataca acaccttttc atggcgttga ccggctataa
    36481 gttcctcagc ggttttgctg cctgtatgtt tcttcagaaa ctcatcctgt atcttgctgc
    36541 atggagaaaa gtaatgctct gtccagcagg tttcaggtaa cgtaaatgcg gcaacaagac
    36601 gataaccggc tttctgcaag actgaaatat tatgacttat cgtgttcatt tcaggaactg
    36661 cgtcaagcca gaacttttcg atttcggcgg ggcggtcatc cgtaaaccac gactcatagg
    36721 tcagggcgac ataaccgtct ttttttagaa agccgttcca ataattcaag ccttttttaa
    36781 agccgatatt ggcgatagcc ccttcagacc agataaggtc taaggattct ttcccgaaag
    36841 gaagatcgtc cattgaacct acaacacctt ttaccctatc ggaaaggtca gattgtttgg
    36901 cgttccgact gaatatattg ataaattcag gaaagaggtc aagcccggta atctgccccg
    36961 gagcattctc tgccaaaatc attgtctgcc ctcccgtacc gcaaccaagg tcggcaatgc
    37021 gggaattatc agccaaattg tcgataaaac tcaacgcttt aagagttgct tctgggctgc
    37081 ccggtccttg acgttctacg tttgaaaagt attcgcagat caggttgaaa tcgaattcgt
    37141 gaattgtttt atttttgtta ctcatgatgt ttttaaataa aagttatcta tctgattctt
    37201 catttcgcca atgctcgggt ttgtttaatt cttcgctgca tttaattttt cctttaccga
    37261 tttcgaatcc ttttgggctt attggttgaa ccatccaata atcactatat tcttccaaaa
    37321 tgggataagg cgcaggataa cctaaatgat tggcatcagg tataaatcca tatttaggat
    37381 aatattcttt atgccctaat acgaacacaa ggtttgaacc tttttcttgt aatttctcta
    37441 taccagcctt tatcagcatt ccaccaatac cttgccgttg atattccggt tttacagcca
    37501 aaggtgcaag aatatgcatc atcggttgct gctgatgttc gttgaaatag gctctggtaa
    37561 aaagaatatg tccgataggc tcgtctttat aaaaagcaag aagtgagact atcggtttgg
    37621 ttgtattgtc ggctaataac tctgctacga gttcggcttc cttatcatag ccgaatgcca
    37681 atttctcaac ttccattata tggctaaaat cgcttgtcgc agtttctctt atttgaatat
    37741 tatttaaatt cattgtatta tgtatgttaa gaacttcaac aaatgcataa cgcgccttgt
    37801 caagctttaa ttaattccta aaggtatatg aaaaatagct cgggcaggaa tatgcccgag
    37861 tatgatggtg ggataacccc gacaggaacg tctgaggtta tttactttac aatttccttc
    37921 tttgttttac acataggttg caaaagtaat ggttttttct gtatttatat tattggagag
    37981 ctggaaatta tatcaaaccg ttttaaattg caaaatatgc ttattataat atctttatag
    38041 tcagaggttt ccaatacagt gaaaatagat aggaaaaagc aggctaactt tgttggcaaa
    38101 ttaagctagg ttcatcggca aagtatgtta agttcatcgg caaagtaact taacatactt
    38161 tgaaagtgga gcaataggta tgtgttaatg atttgtcccc tcgaataaat cctttgaatt
    38221 gttggataag ccattcttta gcttgaactg gttgaacgta tagctaaggg tcaagcctat
    38281 caacgggtaa tcgggccgga ttcgtgtttt ggaaatcaag ttcgaggaag tgatcgtatt
    38341 gacataacgg gccgtattga agacatcccg gaaagagagg gtggccgtca acttccgttt
    38401 gaagaattgt tgccgtatcg ctaggttgac aaaccagaac gactgggttc ttccttgggt
    38461 ggttacggaa tgacctacga aattgccgtc aagctgtatc cttgtgtatt tcccggccgt
    38521 gaaagcgttg ttccaagcga tctcgtaatt ggtactggtc tcattctttc cgtccgtctt
    38581 atactcgttc tctacccggt agtgataaag gctaccgttt atttgcgtat tccaccaact
    38641 ggtggcctgc aaactgcccg atagttctat tccggtggaa taatcatgtc ccacgttcgc
    38701 catggaatcc aaggtaaccc cggcttggta aggaacccgt aatcgttcga tcttgtcttt
    38761 gcgggttcgg tggaataggg aggcagacaa ggcattgtcg ccggaagtca aggaataatt
    38821 caactcgaaa gaatgaatgt actccgggcg tatatccggg ttaccgatct cggctgtata
    38881 gtaatccttg taagtgatgt atggctccat gaaataaagc tccggtcggg tcgtacgacg
    38941 gctgtaagcg aatagaagct tctgattttg tgtgaggtta taaccgatat gggcggatgg
    39001 gaacaactca aaacgctttt gtaggcggtt cgcccaatct ttggagctac gtaatacttg
    39061 atgcgtatgt tctccccgta atcctacttg aaaatcaaaa gaccggtagc tatccccaac
    39121 gatcgcataa agggagttga tcccttgttg gaaatagaac gtgttgtaaa tatcgtcacg
    39181 ccagaagaac tctttggtat ccgggttcca aaactgcata ctataatcgc cgtcttccga
    39241 gtatgagaaa tattgataac ccgccttgat ttgtccggtt ttgctgtatg gaaatacata
    39301 atcggctttc gcacggacgg tccaacgatg ttcggcctcc cacgcacgat gaccttgctg
    39361 gcgtacgttg tttttgtcga acagatcgct ttggaaatat tccagagcgt cgcctccata
    39421 tttcaagaag aagctaccgc taaggttatg ccccttatca ttgaacttat gatccacggc
    39481 cagattccct agtccgaaag tctcatggat atcaaagtcg tcaaggctct tgaactctcc
    39541 gttctcgaat tgctcgccat tagcggaacg ttcttccgta tattccagat ccccttttcg
    39601 cttgagcccg gcatatccgc cttccgcgtt aatagaaaaa gttgtttgtt tttgtgtata
    39661 gctccaacct ccgttgagaa tatatgcgta gccgttactt tcacgggggc cattggaata
    39721 agaagtcgtt gtcgtatcgt ttaccaacgt cgttttctct tgggtaaaat gacttttgcg
    39781 aagtcggttt cccacataac cgcctatacg ccattgagac gccttgtttt gtccggtcaa
    39841 caagaaatcc aaggtccggc tccataccgt attcccgctt aggttgatta ctccgctcaa
    39901 cccttccccg aagttcttct tggtaatgac attgatgatc ccgacatcac cccctgtatc
    39961 atgttgggcg gacggggtgg tgatgatctc tatattctgg atttgtccgg acgggatctg
    40021 ttccaaggct tgggtcccgg taaatatact gggctttcca tctacgtaga ccgtgaatcc
    40081 gctactcccc cggaaggtaa cctctccctc ggcgttcacc cggatggaag gcgtgttctc
    40141 taggatatcg acagcggttc ctcccgagga aagcaggttg gaagaagcct cgatgatctt
    40201 tttatccagt ttatagatga cttgtttctt gttggctacg acctccactt cctgtaagcc
    40261 tacctcaagc atttgcatcg ggataatacc cagatccttg atctgctctg taaggataaa
    40321 ctcctctccc atataaacat catatcccag aaaatggata cggatcgaat acgttcccgg
    40381 ttttacgggc tggattagaa aagaaccgtt cgcttcagtc atagcttctt cgacgatatg
    40441 atctccatca tataatacaa cgtgagcgta gtctaatgcc ttacgggtgg tttgatcgat
    40501 tacgattcct ttaatacccg gattcgcatg gatagatagt agcacgctaa ggaatactag
    40561 cgatagaaaa agttttctca tattttacat tcgttttaga attgataccg caaagctagg
    40621 gaaataggga gggagcgggc cggacatatg tttcataata ccgtacaaat cgttcaatct
    40681 ttctgttttc tgtgattttc acccacttaa tctttatatt tggggcatta atcagatgaa
    40741 tggatgagaa tatacctttt actgctgttt gtacttatga taacgagagc gcaagctacc
    40801 aacgttattt ttgaccggat aacaatggat agcgggcttt cttcttcctc ggtgacctct
    40861 attttgaagg atcgtaccgg gtatgtctgg gttgggacga ctgaaggctt gaaccgctac
    40921 gatggatata cgtttaaagt attcttgccc gtaccggatt gtccggaaag tatacaaagc
    40981 agttctatcg ataaattatt cgaggattca gatggaggta tctggatctt tttttcctcg
    41041 ggtgggatta gccgttatga cagaggttcg gatacatttt tgaatttcac gaaagaatgg
    41101 cttcgacaac agttacgtgt gtatggtagt cctacttgtt tctcggcctc cgttccggga
    41161 catatcttta taggtacgga gaacgggatg ttggagtatg acgctaaaga gaagaaattg
    41221 gtacgccttt cgccggcggg ttcggtagtc tcgtcgtctc ctgtgaattg tttgtattcg
    41281 gcgccggatc attcgttttg ggtagggact ttagctggtt ttagtttgta tgacaaagaa
    41341 acaaaccact ttcaagatta tacgatacgg acaaatgacc gggaggatat caatgccggc
    41401 aatttgaatg gcgttaacgc gatctatatc gaccggtttg attatatgtg gttaggtacg
    41461 ggacgtgaag gggcttttcg ttcggttgat atgggagagc gagagatctt ccaatctgtc
    41521 ggtcgtgagg atactcgggt atatcaattc ttggagaccg gtgatggtga tttctggatc
    41581 ggacataata agggggcaag cttgattagc cggatgaacc ggcttgcctt gcgatgtgag
    41641 catttctttg accggccgga ggatctggaa cctacgggag aatgccaagt gcgatccatc
    41701 ttcgagagta aggacggaac ggtctggttt gatgatagcc gtttcaatca aggtcttttt
    41761 tattattctc cgaaggagag gaaaatggga cagttgagga acgtgccgga agacgcacat
    41821 tctatcagca gtaaccagat tacctgtttg tttctggatg actcggatca tctgtgggcg
    41881 gggcattcca cgtatggggt gagccatgcg gatttaacac cttccttgtt tcgatatacc
    41941 ttgggataca cggaaaaaga gaatctgtct tctcttcata tcctagccgt ttatgaggat
    42001 tcggacctga atctttgggt tgcgacctct aggggattag atcggattaa ccataagact
    42061 tcccgggtag atatgcgttt taccttctca ccccgaaaaa gtccgtcctc tttatccgga
    42121 aagattatag gttctatccg tgaggattcg gagcggaacc tatggatcag ttatcaagac
    42181 gccaacccgg accggttgaa tctggatgat ttccgaatcc gcccttttat accggattac
    42241 caagtctctt atgattatcc gatcaactcg ttgtcggagt tatgtaactt atgcgtgagc
    42301 gaagaatctt ggttttgggg aggagcggat gaggggcggc ttcgggtgtg ggatacgaag
    42361 acgagagcac ttatcacgta tcgatatata ccgggtgaga tgaatcccct tgcgtcgaat
    42421 catattcatt gtctgtttgt ggactcttcc ggttatttgt ggatcggtac gaatgcgggg
    42481 ttggatcaat acgacaagcg aaccgggcga tttgatcatt tcacggtaca ggatggctta
    42541 tcgggaaata tcgtacgagg aatccgtgaa ggtgagccgg gcatcctgtt tgtcagcacg
    42601 aataaagggc tgagtcgctt ggatatacaa aaccggcata tcgttaatta tacgacggca
    42661 aacggtttat tatcgaatga gtttatgggt ggcgcttgct gtaagcgcaa atcgggtgaa
    42721 cttgtatttg gcagtaatga ggggatcgtt tcttttgatc ccgttcagtt aacggacggt
    42781 ttgagaaaaa tacctgagtc tttgcgaatc acgaacctca cgatcggaga ctcacgtgag
    42841 aagcaaggtt tacaggtggg ttttattgcg ttcgattatt ctcatccccg tagtatccga
    42901 taccggtatc gtctggatgg atatgatacg gattggcggg aggtggacgc cagcgatcgt
    42961 acggctatat ataaccgtct accaccggga aactatgtgt ttcgggtgga aacttccggc
    43021 aatggttcct attggagcgc tcccattacc gaacctgtca ggatctttcc tccttggtgg
    43081 tggacgtggt ggtttatttt gctggtattc gtggttgtat gcgtactgtt gtgtatcgcc
    43141 tataagagca gggtgcgctg gtatcaactt cgccaagccg agttggagtg taagatacta
    43201 gaacgtacac ggctgttgaa acaggccaag caagaactgg aggaaaaaga tgcgttgaaa
    43261 actcgtttct ttatgaatgt ctctcatgag cttcgtaccc ctctgacgat aatcaaggga
    43321 ttgacggagg atctggaacg gcattccggt tcagaagaat cttgtggaga taaagagatt
    43381 ttgcgtacga tctcccggaa taccaatcgc ttgattcggc atgtcaatga attgctggat
    43441 ttatcggtat tgacccgggg agtaccttcc ccgcatatcg tttgtgcgga tctcagccga
    43501 ttcttagagg atatttcgga aacctttatt cctttggccg attcctataa aatcgcgttt
    43561 acgtattcga ttgccccgga tatctcaatc gcttattttg acaagaatat cctagagcag
    43621 gttctatata atttactgtc gaacgcattt aagtatacgc cggatggtgg ttcggtaagc
    43681 ttttccgctt cattggagca aagctcatcc gatgcggtca tgactttacg aattacggat
    43741 agtggaatcg gcattcctcc cgaatcgtta ccgtatattt ttgatcgata ttataagggg
    43801 gcatcgatag cgtttcgccg ctcggagagt tcggggatcg gccttgcgta cacaaaagag
    43861 ctattggagt tacataaggc aaccattcaa tgtgagagtg aattggggaa aggttctgtt
    43921 tttacggttg ccttgcctat atcggaagag gcttatcctg aggagtggtt ggagtattcg
    43981 gaacctaaaa tggaagaggt atctttgcgg gaatcagttc cattggaaga aacaaactcg
    44041 gtcccggaga atctacgaca aacgcttttg tttgtagagg ataatgagga tctatgtcgt
    44101 tatttgatga atgcttttca aacggattac cgggtcgtga tagcgaaaaa cggaaaggtc
    44161 ggcttggaga aagccttgga gatcctaccg gacgtgattg tctcggatgt aatgatgccg
    44221 gtcatgaatg ggattgaatg ttgcgaggct ttgaaaacgg atgaacggac ggcccatata
    44281 ccggttatcc tattgactgc tttagcggaa gaacgtcaac aattggaagg gtatggagcc
    44341 ggagcggatg attatctgcc taaaccgttc agtcttgctg tcttaaaagc gaagattaat
    44401 aatctgctca aacgtagtga gcgactaaag ttatatttca gggatcggtt cgatctgcgt
    44461 accccggagc aaacagttgc caatcctgat aaggaatttg tttcgaaagt gacaaggatc
    44521 gttctggctc atttgcagga cccggagttt gatgtcgagc ttttctgttc cgagatggcg
    44581 atgagccgtg ccagcttatt tcggaaatta aagtccacta ccggttgttc cgcttcctca
    44641 ttcacccgta atatacgaat aaagcgtgcc gccgagttat tggggcagca cgcttattcg
    44701 atcggggagg tagctgctca ggtcggcttc tccgatccga actattttac ccgttgcttt
    44761 aaagaaattt acgggatcac tccgagtgag tttattcaga cttcaccgag ttcacaggat
    44821 tctcattcgc cgcttgccag ttccggaaag taacggtacc gatcgtaacc gagagaatga
    44881 ttaggaaagc tacgatgaag acccaaagat ggagtggtgt tttataagcg aaattctcta
    44941 gccactgttg tgttcccatc catgctatcg gaatcgagat gatgaagcaa acggagacaa
    45001 tccggatata agtcttgttg aacatcaaaa gaatctgtcc ggtagtcgct ccgttgatct
    45061 tgcggatacc gatctctttc cggcggtatt gcgtctcaaa tagcacgagt ccgaatacac
    45121 ctacgataga gatcaagatc gccattattc cgaataggga gattagttta cccagtgttt
    45181 gttctttctg atataaatta tttaagatgg tgttgtagaa agagatctcg aaagggaaag
    45241 tcggatcgat ctctttcaat gtttcccgga cgtgggcgac agcttcctgt aaattcgttt
    45301 tcgaattgaa gcggatatag gataccaatt taggattggg tatatcgtta ttcaatgcga
    45361 atacgaaagg cgagcttgcg atccggcaag agttaaaccg gaaatccttg ctgactccta
    45421 gaaccgtacg atcattgaaa cgatctccgg gatgtaagtg gaaatcccgc tctgccgccg
    45481 gattgatgat ataatcactt tgtgccttgt ttaaatcctc ccgtgtaaaa tcccttcctt
    45541 cctctacttg gatatccatg acggaaagga aattctcgga ggcatagaat accttgaaga
    45601 atacatcctt atcttcatga cgggcatatt cgagatcgat catgtcatct tctttcgata
    45661 attcgtagac ggagaaggcc acatcctcta ttcccggata atctttaagt ttctggatat
    45721 attggggctt atgcttggcg tagatctccg gtgtcaggtt cacgatggct acttggtctt
    45781 tattgaatcc tagttgctcg ctagaggtca tgaaatggtt ctgaagtccc atgaataagg
    45841 tgacaataat caaggcgatc gataccgtgt attggaaacc gatcagggcg acacgtactt
    45901 ttttcccttt gggactaaga ccgaaagagc cctttagtac caaggccggc gcataggagg
    45961 tacttcgtat agctggataa agtcccgcca agcaacccgt caagatagcg atcagtgctg
    46021 tgagaaggat caggcctttg tattgactaa gacgtatatc cgcatctacc taattagcga
    46081 tcggtgtgta agacaaatcg tttacgatga ataaggcgag aatgtaggat atcaagcaga
    46141 tcacgatcga ttcaatcagt gagatggctc gtaacttata gatggagcat cctaataccc
    46201 ggtgcgtatt gatcgttttc aatcgtaggg gaatcaacga ggttgtgaga ttggtaaaat
    46261 tgattccggc gatgaataag atgaggaaag cgatacccag taacacataa tttgtctccc
    46321 ggtgaccttt cggattaaag tcgaaagttg tatcatgcgt gtaataaaca tcctttaagg
    46381 gggttagacg taatgcgatc tcttgcgctg aacccatttg gcttttagcg aaatcgaaag
    46441 tcttgttgaa atgatccaat acctcctctt tatttagggg atcgtctagc gtgacgtata
    46501 tttcgttggc atacatttgc caagaacttt ttaatagatc cagttggtcc atcgggacgt
    46561 aaatacggtt ttgtactgta gtatttcccg ggaaatcctt atagacacca ccaatagtaa
    46621 gtatcgtggt acttacaggt tgccagccac tactgccgga catccggata cgtttaccga
    46681 tagcggattg tttgtcgaac agccttttag cgacactctc tggaatgagt acggagccgg
    46741 gaatggatag gcatccgacg gaaccttctt tcatgtggaa atcaaagaca tctgagatat
    46801 tgggtagaca aagctggaag ttttccttga agactttcgc ttctccttga tcgtctacct
    46861 cgtcgatttg gcaataccgt tctcctccgt agaatggata acggtaggag taatccgtga
    46921 tatgagcgga tgagttaaca aaagcatcgc taaacattag gcaatggatg gcgttatgct
    46981 cgaattctcc gtgatttgcc tctagccgga aggttcggct cgatttactg tgcatggcat
    47041 cgtaattcat ctcgtaatcc acctgcatta ctatcaggag gaaggcggcg aaagcgattg
    47101 tcaagccgaa gaggtttaac acgacggcgg tcttaaaccg cttgaataga taaagtaagt
    47161 ttcgaatcat tagtttcatt gtaacaggtt ttaaatatat tcatttttta gaaaagaggc
    47221 aaataatgtg ccatcgatgt aacgttctgc taatcataag ataatagaaa aatgcttaga
    47281 aacgattgtg tgtgccttcg cacggtgcac gttcgctttc gcacgttatt tgattttaat
    47341 tcgtaagttc gcggatgttt taaatacaga aagataattc ggaaatatca gcatggaaac
    47401 ttcaaataga ctctgttatt ggttcctttt ttataaagac caactgttgc ttcagaaaga
    47461 gaatgatacg tataccatcc cttatggcga gaatccccca gttccggttt ctcatacgct
    47521 agaggttgat taccgggatg gacttcccgc gcgtacggca gaattggata ctccggtgga
    47581 ggggaatgac cgttacgtac atatggggtt gcgtgcctct tgggattata tctcgagagc
    47641 gtgttacgag aaggcgggta aggcttttca attgctttat tgggatagcc atagccgttt
    47701 ctgcccggta tgtggtactc ctaccgtaca gactacgtcg atcatgaagc aatgtccttc
    47761 ttgcaaacat gagatttatc cgacaatctc agcagcgatg atcgtcttga tccgtaagga
    47821 ggattcgatt cttttggtac atgcccgtaa tttccgggga actttccatg gattagtggc
    47881 cggattctta gaagttggcg agaccttgga agagtgtgtg cgtcgggagg tccgtgagga
    47941 aacgggttta gaggtcgata atatcactta tttcggaaac caaccctggc cttatccgag
    48001 tggcttgatg gtaggctttg tagcggatta tgtaagtggg gaaattaagt tgcaggatga
    48061 ggaactaagt tctggtgcct tctataccaa agataactta ccggagatcc cccgtaagtt
    48121 gagcttggcc cgtaagctaa tcgattggtg gttggatcat caatgaggag tccttttttg
    48181 cggcctctgc ctgttgtctt tcgaatttct tccttttaga gatgacatcc ggggtaggga
    48241 ggttaccgta gttttgccaa gttccgttgc gttttgcgtt gcgtttatgg acatatgttt
    48301 tccggctggt catccttcct aaatcgaagg tagctagtga ggtacgaccg ctggacggag
    48361 ttcttttcaa ttcatctaag atagattgat agacaggcag tatcttttta tacggtggat
    48421 tatgtcgcca gaataccgat ggcggtaaat ccttcaatgc tacttttcgg tgtgtcgtat
    48481 cgtcttgttg gatatattct gagaaatctt tggtgatagg gatattgctg ggagcggcca
    48541 gttgaggttt ccccatcggt tttcccggtt ccgggttgag gaaagaaccg ctttggattg
    48601 ctttttggaa ttcagggttc aatttgatgg aatctttgcc cgctaataca tcctttagcc
    48661 agatcgaatc ttgctcagtc cattgcgcat agcctaagtg tatatttata cagacgaaaa
    48721 atccaatcaa tagtggtctc atgaatgcct gaattgttaa ttgtgttcaa agatagtctt
    48781 ccttctttct cctcgttttt tctttcgctt aaatagtctt accgtttact taatcttaac
    48841 cctctttgcg gactattaat ttaacagttc atctgtgcac gataatcgtt cgattacgca
    48901 cgcttcttcc attgatttaa tacctacctt tgaggcatca caaactagtt cagcgcttat
    48961 gaaaaaggga aaactattaa ttatagatga taatgaggac atcctttttg cccttaattt
    49021 attactggag ccctatatgg aacaaataag agtggctacg caaccggagc gcatcgatca
    49081 tttcatgcgg acttttatcc cggatattat cttgttggat atgaatttca aacgggatgc
    49141 tattagtggt caggagggtt tctattggct ggagaagata aagaagatag acccggacgt
    49201 ggtggttctt tttatgactg cctattcgga tacggataag gccgtgcggg cgattaaggc
    49261 aggagctacc gactttatcc cgaaaccttg ggaaaaggag aaattactcg ctacactctc
    49321 ttcggcattg gaacttcggg agagtagggc ggaagtgcga aatttaaaga aacaagttga
    49381 gattcttagt tcacccgagg atgctggctt cgagatcatc ggtgaaagcg aaccgatgca
    49441 ggctattttc gctacggtcg ataaattaaa gaatacggat gccaatatat taatcttggg
    49501 ggagaatgga accggtaaag atttagttgc ccgcgcctta tatcatcaat ctccgcgttc
    49561 ggggaatctt ttcgtcggga tcgatgtggg ctctattccg gaacaacttt tcgagagtga
    49621 attattcggc tatgagaaag gggcttttac ggatgcccgt aaggaaaagc cgggacgaat
    49681 ggaggtagct tccggtggca ccttgttctt ggatgagatc gggaacttaa gcctttccat
    49741 gcaagcgaaa ctgttgaccg ctttggaaaa acgacagata acccgtttgg gagcaacgca
    49801 acccataccg attgatatcc ggttgatctg cgcaacgaac gtgaatatcc atcatcttgt
    49861 ggcagaaggt actttccggc aagatctttt atatcgtatt aatacgatcg agttacatat
    49921 tcctcccttg agggaacgag gaaatgacgt gatcttattg gctgaacatt tcttgtcgaa
    49981 gtatgcccgt aaatataaga aagacttgaa gggcattaac agggatggga agaataagct
    50041 acataattat gcttggcccg gtaatgtacg tgaactgcaa catgcgattg aacgggcggt
    50101 tatcttgtct gaaagtaatt ggctaaggcc ggaagacttt attctgcgtt ctgtcccgct
    50161 tagggataag gaaccatccg atgagttaaa tttgacgata ttggagaaag aagcgatcga
    50221 acgtgcctta cgtcgtgccg aggggaatat cactcgtgcc gccgagcttc tagggattac
    50281 ccgctttacc ttgtatcgta aattggagaa atttggctta tgatacgtta cttgttgttc
    50341 gctcgtattt tggggatcgt ggtcttgtct tttactgcct cattcttaat gctgaaaggg
    50401 tttttgttta ttcccgcgct gttcggattt tgtattcttg cgctttcggt tttcttatat
    50461 aaggatcagc aaaagactgt taagcggatg gaatacctga tagagagtat tcattacggg
    50521 gatctgagcc tgttttatcc ttccgattca atgacggaag acgaaaaggc tttggcctct
    50581 tctatgaacg ctgccttgga ggctttacgg agtcgattgt ataattcggt ggtcgctgag
    50641 gcggaaaccg aggcatggca gaaacttatc cgggtattga cgcatgagat catgaactcg
    50701 atcgctccgg taatctcttt atcagagaca gtagccgagc gtgcgacgat aaatggcatg
    50761 aatgagagag actacgctat catggtacaa gccatgcaaa cgatccaccg gagaagtaag
    50821 gggctattgg attttgtcga gaattatcgg caattaaccc gtctgccttt acctacttta
    50881 cgaaacttct cggtttcggc tctctttgac gatatccggc ttctatttcc ggagaagtcc
    50941 gacatcctct tctttcgtgt aaaaccggaa gatttaaatt tatatgcgga tcggatcatg
    51001 ctggaacaag tattaattaa tctattgaaa aatgcgatag aggcttgtga agagtcctta
    51061 tctcctcaaa tagtcgtgga ggctgtccaa aaagccggca tggttattat ttcggtgatt
    51121 gataatggta gcggaattgt tcccgaggcg atcgacaagg tcttcgtgcc tttcttcacg
    51181 actaaatcta aaggttccgg tatcggacta agtctttgcc ggcagatcat gaaccgtcat
    51241 ggaggaagta ttagtctcga ctctcaagta gagaagggtt cctctttcgt cttgcgtttt
    51301 ccgattgtta ccaaacggat tctataaata agtattaata catgcgatta gcttatccgg
    51361 cttgatcggt ttagcgatgt aagaggagaa tccactttgt tttacccgtt cctcatcctc
    51421 cgcgaaagcg aaagccgtta cggcgatgat agggatggac tggctctttt cccgaattac
    51481 ccgtgtagcc tcatagccgt ctacgatcgg catttttagg tccattagga ttaagtccgg
    51541 ttgatattta ttgaataaat cgatcgcttg ttccccgttc catgcgtgta taaggttata
    51601 atctttcaac atggcttgga ataaagtata gttgctttcg ttatcttccg ctattaatag
    51661 ggttgccgat ttggatgact ggctcttctg tacattctcg gtttttggtt tctcatgcgg
    51721 gacttcctgc atctctagta tcgaataggg caacgtaaac cagaatgtag aacctttccc
    51781 ttgctctgat tccaccccta tatctccacc cagacgcttg ataatcatct ggcaaatcga
    51841 taatcccagc cccgttcctt gcacaaagct atttaactta acgaaacggg tgaaaacttg
    51901 accgatctta tccttggcga taccgcatcc cgtatctttt acatagaaat acaactcatc
    51961 atctctatgg cggtagccaa acaggatgct accttgagtc gtgaacttga tggcattgtt
    52021 gataaagttc gtaatgactt gggagacccg gttacggtcg gtgcgtaaga tacaattcgg
    52081 gatcttctcg acaaagcata cctgcacacc atcttgcgcc ttcaaacggg aagactgctc
    52141 gatatcggag aatagttgat tgacatctac gtctgaatcc acgaattcta gcgtacccgc
    52201 ctctatcttg gctagatcga gaatatcatt gatcaattgc aatagcaggt cgttgttgct
    52261 attaatgata ttgatatatt cctctttatc ctccatattc tcggttacgg ccaataatcc
    52321 ggagaaaccg acgatcgcat tcaatggcgt tcgaatctca tgactcatat tcgccaagaa
    52381 cgcggatttc aaacgatcgg actcttccgc tttctctttc gctttcctca gttcgttctc
    52441 cgcctgtttt tgttttgtca catcttcttt cttgaaaata accccgataa ggttgtcgtg
    52501 ctcgtctaat acagggttcg ccaaaatatg aagatacttt ccatcgccga actcattcgt
    52561 gatatcgacc tgctttttgg tttccatggc ctttgcgacc gtgcaacggg tacaataagg
    52621 ctttactccg ttcttgacca agaagcaatt agccggaccg aattcaggga tacagtcatg
    52681 gaactctacc tcatttctcc attttacggt ataatccggc ttgatgaaat agatggaagc
    52741 ttggatatta ttcatgatta gtatattatc cttctgtaga tccaataact tatctttcag
    52801 tttattggtc cggataaaga agattaatat cataatcagg aaaataaaca atacggtgat
    52861 tacgcttagc aagatctcga acctgtattt ggagaatagg ctcgggtcct cgttgataat
    52921 agtagcgtcg tggggcaatg acaatctgct gatatcaaaa gccttgatct ttgaagcgtc
    52981 gaacatatat ccattgggaa tgatttgtgg atggatatct ttaggggcga ttttcttctc
    53041 caatatactt aaagcctctt tcgccaaatc ggaacctata ggcctgtatt tgggactgaa
    53101 acctccgatg gcccagtgcc ctatgccgac ggatgccaat gtgaatgtcg ggattctggg
    53161 attggcggtc atcatggtat acgtggcatt tccaacataa tacccgtcgt tcacgtctac
    53221 acgccatgta ccaatcaata tcacggtctg atccggcagg ttcttgattt gctcaacgat
    53281 ggtgtagata ttattctttc ttccatccag taatatcaag ttcagatcct tgatattttc
    53341 catttccttt tttaccaagg tctgcatagc taaaccaccg taggtattat cggtgattaa
    53401 tgctatattt tgagtttggg gatatagctt acgtattaac cggatatttt cttttacgtc
    53461 ataagaatac aagaacccgc caaggtgtaa acctttatct acgtactctt ggatatcgat
    53521 gtatttcggt tcccattcgg cgacatttaa atccgagtcg ggtaataaga tcgcattctt
    53581 actgatcata ccgcataaaa ccggtatatc aggcttgtat tcttgggaga tataagaagc
    53641 ccatgcctct tgacctaaga taatgataag ctgaggggtg ttattttctt tatatttatc
    53701 caatatacct ctcatcttac cgtcccataa gggggcttcc gggaggctct tacagttcat
    53761 gttctcgata accactggcg agataccacc tccccgctta tattcctcca taaactcgga
    53821 aatattggcg gtcgtattac gtgtatcggg attgtaggag ctaatgatta aaatagggcc
    53881 tgcattatct gtagcgtata agtggaaaga aaagaccaga cttaacacga taaagagtac
    53941 gaatcgtatg tagtatttta ataatgtcat tctttaccta cctattcatg tgcttatttg
    54001 cgattaaagt actatttttt gttcatacag tccacaaaag tagaaaagat ttatgattaa
    54061 ttgctgaaat tcaaaataaa aagaatctat tacgcctaaa atctataact cgatcatcac
    54121 tccgatactt gggagaagcg ttcctgtaag acgttctatc ggtcttaatt cgtaccgttg
    54181 ttcatatatg ggagcttccg ggttgataat tttacccgtt ttgatatata cgtcttgctc
    54241 tttgtatttg gaattcaata tgttttggat gtcgatatag gctccaagca tgatcttttt
    54301 gaagtaaaat gttttatcga tacggatatc taactgcgtg aatggcttga gccgttcgct
    54361 gttaaaccgg ctgtaatcat agtatagccc gttattagcg tcccaagctt ctacataact
    54421 actcttttct acatcgtaag gcgtataggg agcgcctcct actacccgga acttggcgcc
    54481 tacgtcccag ttcttgggta aagaataagt cccgctaaac gtgaacagat gcttattgtc
    54541 ccaagccgag ggaagataag tgtccatatt tctcccatcc ttgaattcgc ttcttaccaa
    54601 agtgtaggat gcgatgaaag taagcccttt ataattatac caacgtccca tgatctcaag
    54661 tccataagct cgccctgtag cggtagacga tacggcctca tttcccaaga caccatagtc
    54721 tgtacctttc gatgcgagtg ggatactgtc gagtatggac atcggataac gatcataatg
    54781 tttatagaat ccttcggtcg tgaatttcaa gtatgaggta ggacggtatt ccaagcctaa
    54841 tccggcttgg tcgcttcgga tatagcttaa atgatttgtc cggtttacat aattaccttc
    54901 attatccttg aatcccaatg tcgtataagg aggaagctcg tagtagcgtc cgatattcgc
    54961 gtttatataa agcggatcgg acaagcggta ggataaggat aggcgaggag ataactgatc
    55021 taacaaatta ttcatatccg aggaataatt gtttgcgtcc gcacgaacac ctaaagaggc
    55081 ggtaaaccgc tcgttataac tctcataaat agccgtggca tagatacccc acttccatat
    55141 gccaaggtct gtttgatata cgatggtacg ggggatagag gtaaattgct tttgataggt
    55201 gtcattcgtg tattgggcgt attcgatgtt tcctccgaca ttcaattgaa tgaatggtaa
    55261 gcggaacgtg ttttccgttc ggaacttatt ctcgatctca tccgaacggt aatttaagga
    55321 gagattctct tccttgcttt cgtcattgtc tttgtattta atattcttat tgttggtctg
    55381 gctacggctg ataatgaccg agtagagatt tttaccggcg tagtgtttat aaaccgctcc
    55441 aagggtatac gttttttgtt ttacgaccgg caagtaagag aggatatatt ggtttttctc
    55501 gctcatgtct tccattcctg tattcagctt catatcatcg atcgccccta atccgagaac
    55561 tgtaagctca ttcttggggt tgaaggagtg cttaatcttg aattgggcat ccgtgaaagt
    55621 aggtaagaac ggcaagccga tcatatcgaa aaggaattga aggtaagaac gacgaacaga
    55681 cacttggtaa gtggtctttt ttcctagcgg tccattagcg gacacaccga tatctgaggc
    55741 tcctaggact cctcgcaatg agaatttttc cttatttcca tcttgtagtt taaaatccaa
    55801 tatcgaactt aaagcgttcc ccttggatgc ggggaatgcg gccgaataaa agttgacctc
    55861 ccggataaaa tcgggattga taataccgac cggacctccg gaggctcctt gggtagagaa
    55921 atggttgata ttcggtatct ctacgccatc caaaaagaaa cggttttccg agggacctcc
    55981 tcctcttacc atcaagtcgt tacgaaacgc tgccgtggac gctactccgg gaaaggtttg
    56041 tactacccgg gagatatccc ggtttcctcc cgcgcttttc tctatctcct tgaaaccgat
    56101 tacacggagt cctagcggac tttcggcggt tttacggaac ggagaggcta ctacgctaac
    56161 ctcttgcaga ttctggctgg cttcctctag ctcgatcggg aagaatatat ctttattcgc
    56221 tagtctgaat tcggcggtaa cgaatggctt atatcccaga aaggaggatt ggagacgata
    56281 gcttccgggt gatatgccgg atatctcgaa taatccggtg gaatcggtga ccgccccttg
    56341 cgtcgtgttc cataccacta cgttagcgaa aggtatcggc tgtccgctcg atgcgtcttt
    56401 tacaactccc ttgatagaga aggagcgctg ttgaccgata gcggcttgta tggtacataa
    56461 taagaatagt aagaagtaaa gatggcgtct atccatatct tatatcatat ttatagcggt
    56521 aaagataagt attattctga ttcgtatgta ttatctttgc atacatatgg agaaagaatt
    56581 acagataacg gcggatggaa gccatacgct atatattccg gcgatggatg aacattatca
    56641 ttccgtgaac ggggcgttgc aggaatcgag acatatattt attgaggcgg gattgcatgc
    56701 gcaggagaaa gactttatcc gaatcgtgga agttggcttc ggtacagggc tgaacgcctt
    56761 cttgacattg aaggatgtcg agctatctca agcacatcat attgattatc ataccgtgga
    56821 gttatacccg cttcctttag atacgattcg tgccttgaat tatggggagc tgatctggcc
    56881 ggagagaaaa gagttattct tagccttgca tgaggcggag tggaatactc ccgtttcaat
    56941 ctcagagcgc tttacacttc ataaaataga aggaaatagt aacgcctgtg aactaccgga
    57001 tgatatcgat ttgatctatt tcgatgcgtt tgcgcccgag aaacaaccgg agatgtggaa
    57061 tcaggaaatc tataatcgtt tgtatgctca taccgcaccg ggcggagtga tcgtaaccta
    57121 ttgcgcaaaa ggagaggtac gcagaggtat gcaagcggct ggttttgaga tgagccgtct
    57181 tcccggtcct ccgggcaagc gacatatact taggggtatt aaaaattgag aattgaaagt
    57241 tacagagcgt attcctcggt attttcaatt ctcaattctc aactttcaat tatttaagca
    57301 ttgcctcgat cttttctacg aacttatcct tagccgtagc gcctactact ttatcaacca
    57361 tcttaccgtc tttgaagaaa agaacggtag ggatgttgcg gataccgaat tgtccgacta
    57421 catcgtcatt ctcgtcaacg ttcattttac cgatcgtcac acgaccttcg tattcggttg
    57481 ccaactcatc aatgatagga gataccatgc ggcaagggcc acaccactct gcccaaaagt
    57541 caagaaccat gggctttccg gagttaacca actcctcgaa attagcgtct gtaatttgta
    57601 gtgccatttt gaattacgta ttatttaatt atgaattata atctaatgat tgttatgacg
    57661 ccaaaagtac aaattctttc agcgtcgtac aactttaacc attaatttta aaatcgatat
    57721 tctcgttctc ctgtaaaaag tctaccagct cacgggtcac gtttaagcgg atattttggg
    57781 agaagagatt tagggaaata ttatgttccc catcgacaac cttaaaatat aacaggctat
    57841 ggcccggatt gttcttgatc aataccgaaa gctcattgat tgtcggctcg tccaaatcat
    57901 ggatcgggac cgtgatactg attttctcga tcagcttgtc tttctcgtct tgcaaaaggt
    57961 tgacggtacc aatcttgaag tccagtttat tggggtccca gcggctaggc tctacacggg
    58021 cggtgatcaa gagatacatc cctattttac catacttgct gtattcgata taatcctgtc
    58081 cgaaaagcgg gatctcgcca ctacccgtga aatcctcgat cttcaagata ccgtaaggct
    58141 ttccgttctt ggtcattcct tcccggaaac cggtgacgat accacctaat aaaacttccc
    58201 ggccttgtaa ggtttcccgc tcgttaagtt ctaccatgcc ggtattacat acatacttta
    58261 atatgatacg gtattcatcc aacgggtggg cggataggta aataccgacc aactccttct
    58321 ctttattcag gcgttcgaga tcgctccaac gctcgcattg cgggatctcc ggtttagcga
    58381 tggcgatcaa ggcgtctcca ccgaataaag agttgactgc cgtgctctta tccatctggt
    58441 atttgttacc atagcgaacc aaggtatcca agaacaattc cccttttcca ctgtcggtga
    58501 agaactgctc acgctggata ccgaagttat cgaacgctcc ggccaaagcc atggactcta
    58561 tgtttttctt attgcaagcg gtcaagttca cccgttctac gaaatcgaag atactcttgt
    58621 acgggccgtt cttcttgcgt tcctctatga tattttgtac ggcggactca cctacgcctt
    58681 tcacggcacc tagcccgaag cggatgttct tgttcttatc tacgctgaac ttcaagatag
    58741 actcgttcac gtccggtccc aatacttgaa tacccatcgc tttacattca tccatgaact
    58801 tcgtgatatc cgtgatattg gataagcttc ggctcaagac ggcggccata tactcggacg
    58861 ggaagttcgc tttcaagtaa gcggtctgat aagccaccca tgaataacaa gtagcgtgac
    58921 tcttattgaa tgcgtatgag gcgaacttct cccagtcgga ccagatctta tttaaagttt
    58981 cctctttata gccgttggct tgaccaccag ccataaattt agacttcaag tggttcatct
    59041 tctcgatcaa cttcttaccc atcgccttac gtaaggcatc actctcacca cgcgtgaagt
    59101 tagcgagcaa acgggataga agcatgacct gctcctgata gaccgtaata ccgtacgtat
    59161 cttttaggta gcgttccatg acgggaatat cgtacttgat ctcctcctta ccctgtttac
    59221 gggcgataaa agaagggatg taatccattg ggcccgggcg atacagggcg ttcatggcga
    59281 tcaagtcctc gaatttagaa ggttgcaact ccttcaaata cttttgcata ccggcggact
    59341 cgaactggaa tgtaccggtt gtctttccgt cgcaatacaa tttataagtc ttggggtcct
    59401 ccagactgat atggtcgata tccagatcat gtccggtagt cagtttcacg ttctcgatcg
    59461 cttccttgat gatggacaag gtcttcaagc ccaagaagtc catcttgatc aatccggttt
    59521 cctcgatcac ggaaccctcg tattgggtaa ccagcatctc ctcgccggta tccttgtctt
    59581 tcgccgtact gacaggtacg acatccgata tatcataacg tccgataatg acaccgcagg
    59641 cgtgtacacc cgtgttacgg acgttgcctt ccagcatctg ggcgtatttc aaggtatccc
    59701 gtgccagcgg atcatttccg ttagccgcct cttttagttc cggcacatac ttgatggcgt
    59761 cgcccaattt gaacttcttc atgtcaggga tcttatccgg aaccaatttg gctaaccggt
    59821 tcgattcgga taacggtaat ttctgtaccc gggcgacatc cttgatagcg gacttggtag
    59881 ccatcgtacc ataagtaatg atatgagcca cacgctcggc accgtatttc tccgttaccc
    59941 agcgtaagac ctcgccacgg ccatcatcat cgaagtcggt atcgatatcg gggagggaga
    60001 tacggtccgg attcaagaaa cgctcgaaca ggaggtcata tttgatcggg tcgatcttgg
    60061 tgatccctaa gcaataagct acggcagatc cggcggccga accacgtccc ggtcctacgg
    60121 atacaccgag ttcctcacga gcagcacgga tgaaatcttg cacgatcaag aagtagccgg
    60181 ggaaacccat ggtcttcatg atatgtaact cgaagttcag acgctccttt acttcatcgt
    60241 tcaaggggtc tccgtaaagc tccttggctc cgtcgtatgt caatttcgcc aaatagtcgg
    60301 cttccagctt gatgcggtat agtttgtcgt atccacctaa tttcttgatt ttggagtgcg
    60361 cctcttcctc gcttaatacg acattaccgt tctcgtctcg ggtgaattcc tcaaataaat
    60421 catgctctgt taatttctga cggtaggact cctcggtacc gaactcctcg ggaatggcga
    60481 aagtcggcat gataggaccg ctgtcgatgg agtagaattc tattttgtcg gctatctcga
    60541 gcgtattact caaagcttcg gggatatcgg cgaagatggt gttcatctcg gcggttgtct
    60601 tcatccattc ttgcttggag tagcgcatac gcttggggtc gtccaagtct ttgccggtac
    60661 taaggcagat caggcggtcg tgagcctcag cgtcgtcggc attgacgaaa tggacgtcgt
    60721 tggtggcgat tagcttgata ttatgtttgt gagcaagttc gatcagtacc ttgttcacct
    60781 cttgttgatg cgggaaaatc gtgcaatcgg cgttggggtc gtgtgtctcg tgccgttgca
    60841 tctcaaggta atagtcttct ccgaataagt ttttgaacca tttgatagac tcctcggcct
    60901 tatcaattcg tccgtgcatg atatgctgtg gaatctctcc acctaaacag gcggagcaga
    60961 tgatcagatc ctcatgatat ttctccaaca attccttgtc aatacgcgga cgtccgtaga
    61021 atccttccgt ccatgagagg gataccatct tgatcaggtt cttgtatccg ttcttatttt
    61081 tggccagaac gatcaagtgc cagccgctac ggtcgtcttg cgaggccagc ttgctatgcc
    61141 ttccgttgcg agcgcaataa cattcgcacc cgatgatcgg cttgaagatg gaagctttcg
    61201 cttcggcgat ttgtttttgt agttccgtta tcctttgttg ttcctcatcg gttggcgcat
    61261 ccttggccag cagcggtttt agttctttct cggagtcctt gatgatcccg agaggtttac
    61321 tgttcttttt gctaacctta ttgaaaaact ccttgatacc gaacataacg ccatggtctg
    61381 ttacggcgat cgcacgcatt ccgtctttgt acgctttgtc gatcaacgcg tcgatggatg
    61441 cctgtccgtc cagcaaggaa tactgggtat gtacgtgtaa atgaataaac ggttccatat
    61501 atattaatgt atagtctggt gcatattgaa atgagtgcat aaaggtagga aatatttttt
    61561 agtacgagag aggttgtttt gcttttaaaa aaacacgtac gtcttttttc ggaaacacgt
    61621 acatgttttt ggaaaaagac gtacgtgttt tctgaaggat ataatgaggt tataatatgt
    61681 gtgattctat agaatctata tgttatataa acagatgttg tattgatatt ttgcttgata
    61741 taagccgtat atcgtgacag gaggttttcg tgaggtgctc gaactagcgg atggaagata
    61801 gttatgaatg gcgtttttct gtgtgaaaag ccgttttata ctgtacttat gcttggaaaa
    61861 agcgaatctc agggagttct gtttacaaag tgtcattttg ctagaacaag ggaaactaat
    61921 attccgatct atcgcaaaag gtgatcttac ttttgttgat tattcgatgg tgtatttact
    61981 aatgtacgca tgtacattaa ataatagaag agaaaaatga ttgatttaaa cgatcgtttt
    62041 aattagtcat ttgcaaaggt acgcatttct ttgacacttg caacccttct gtgttatttt
    62101 tttcatgcct gattcgcttt cttatcaata ggataggcta tcctttacga aacaagctct
    62161 tccttccaca aactcccctt tgtatctctc gaaaaacgca agatctaaac gatggtttag
    62221 actagtcgtt ttctaacggt agtctgctat cagaaaatag ctaagtgctt aattaacact
    62281 attattaata ttaaattcta aattatgaac agaaagattt ctacattgtt aacggcgggt
    62341 ctgctcgtgg cagggtcgct gtgcggtagt gccttcgctc aaaactctat tcaaagttta
    62401 ttgggcttgg gtagtgctgt tacggaactg aaatccggag cttatgtgat gacggatgcc
    62461 aacggtttag cgtatggttt tacttctgta agcgaggatg gtgtattaca agaaggtatt
    62521 cttgattata aagctacttc tattgcggat gacaagaaag atgatgtaaa gcagtatatc
    62581 tggaaagtta ccgtaacaga gaatttgggc gcttattcgt acaaatttga gaatgtagcc
    62641 acaggtaaga ctctacgtgt caacacgact gctggttcag aggccgtaga attgaatagt
    62701 gcggcttctg gaaatgtgat taaagatgtt tttgcatttg gagctactca aatcggaaca
    62761 acaggtaaat atactgcaag cgagaaggct ctattcgctt ataacgggaa taagagtgat
    62821 gtattccagt taaaatggag tgctggtggc tctttaattt caactacggc ttcgtctttt
    62881 gatttatctt tctatgcggt agaatcagag gaattagggg ctgtgggagc tgatgagttg
    62941 aatgatttgt ataacacggc aggtttctct ttcgtctcaa aaagattgga ctccgatcag
    63001 actagcgagc ctaatggtaa tctattcaat gagaaaagaa tcgttgcccg ttatgtgcct
    63061 tctgacttga gagtggacgc tacttcttat ccttcctatt caggaagtac ggctgatttg
    63121 aagattcccg ctggtatgta cttctttaca gagaatgcac ctgataagga tgattgtagc
    63181 ggagttaatg ctgtttctag cggttataaa gcttggatgg acgcaactgt cttggtttta
    63241 agctcaaccg aaacagtgga aggtacaaat gcgggacgtg cgtctggtga tggattcatg
    63301 ttggtagaga aaaagatcag cgagttgaat ttgtatcaag gaacttcttc caactggaaa
    63361 gccgctggcg atgagatctc cataaacaac gctaacttcc gtgtacagaa gagttattcc
    63421 gagggctatc cgtatgagtt gaacgtggat cgattccgtt accgcaaaca agcgagcaaa
    63481 gcggatcaag cagatgccaa ggtgaagttg catatcttga agcacaatga caactactat
    63541 ttggccactg cttctacttt gacggatgct agcaataacc caattaacta ctttatattc
    63601 aagcaaggtg ctgccgggat gaagagcggt attgagttgt tgaatacaga ggcgaaggtt
    63661 tctgcttata caatccgtgt cttagatggt aagggtgtcg ataagaaaga catcaagagc
    63721 gtatatggaa agtatttgac gaatgctgtt aagagaggtt cgttccaatt tgttgcgaaa
    63781 gctaaggttc tttctcaatt ggaaactccg gcttatcaat gggctatttc cagtgtagac
    63841 gatacatata aagtgacatt cacgaaccgt gagaccggcg agtatttcca agctagcttg
    63901 ttcccgaaaa ctgatttagg cgagaatgtt tacgaattgg ctacagataa caaaacagtt
    63961 accgctatct acgtaaatga gaacacatat cgtgaggcag agggcgatga tgctgatatg
    64021 caacagctaa tcgtggaatt gactccggca gaagttgatc catacgctgg tttcttgaac
    64081 gtggacaatg agactttggt gacgatggct tttgctcgtg ataacaacga gacttctaat
    64141 aagtggtatg tggcagctac cgaaaataat ttgtctttag caacttcaga gtatatattg
    64201 aataagaatg ataagttcgc aaatgaggta tctggcgccg ctcaatggca attggtgaaa
    64261 gaggataaca aacgtacgat catcgagcgt agctttgttt ataacaagga tggacgtgtg
    64321 actgtacaag ctagaggtga taaggcttat gcctatgttt atcgattgca gtatatcaat
    64381 gatggcattg aaaccgagga atacttcccg gcaggaagtt ctaacgtgtc tgcccaagag
    64441 gaattagttg acgaaaataa cactacacgt tttgtgatta agcaagctgc tgatggttct
    64501 gtttatttga ttaaggtgac aagcacaagc tcaaatatcg cttctatttt aaatgcgaat
    64561 acgacgtctg tagtagacgc tacttataag gcttctatcg acgaatgtca atatactact
    64621 ccgtcttctg tttatgcatg gcctatcgct acaactccga gtggtcaaca agattggtta
    64681 ttgaatactt acttgattgt tgaggctccg gaaatcagct atcccgctga ggaaggacat
    64741 atttccctga taagcgagat gaacaactat atctccatga acgaggatcg tgatggtatc
    64801 gttgtaaacg agaatcaata ttctttctac ttacaggtaa cagataagga tgcggtagtt
    64861 ccttctttct atatctctaa caaaggtacg gttgaggatg gtaacagact gttcttattc
    64921 aatccgaaag actctgtaaa ctactatgtg gcagacggta catacgacag aaagtatcaa
    64981 tggaacgagg atgacacgaa ggctgtcttc aagccggcca ctctttggga aagtaaggat
    65041 actttgacta cgatcgttaa aggtaacaag gttgccgtgg ctaaagaggc tgatgatgag
    65101 ggtgtattag gaggcttgga caacttcaag gttcagatca tccagtgtga ggacgacgag
    65161 aacgcttatc gtatccgttc tgtagctgat aagggttctt atttatatgg tgtcaacgat
    65221 aaattgtctt ggagcggtaa caagaaaaac gctatgcgtt tcactatcgc tgctggtgat
    65281 cctacttcca atgagtctat cgctgatgct gccgaaggca tcaaggttat cgcaggcaac
    65341 ggtacgatcg agatccaagg tgcggctggc aagatggttt ctgtaacgaa cgttcttggc
    65401 aagtctatcg ctaacacggt tcttacttcc gataacgcta cgatcgctgc tccggcaggt
    65461 atcgttgtgg tgtctgtaga aggcgaggaa gctgttaagg cagtcgttaa ataagaataa
    65521 tgacgataaa taacataaat cgaaaatcat tcctgcggga gttgtagtga ttcaagtacc
    65581 ccgtgagggc gaataggcgg gaatggatta atattaatac taaagtaata aattaaagtt
    65641 catccaccgt tgcctccgtg aggagggaag gtgggaaaaa aatagcctcg gtcgtttctg
    65701 cgatcggggc taacttttga gcggcccttt catgagttgt tctttttatg tagctttcct
    65761 gtatgtttca gtaggataaa tgtagatgtt attgaaaaat gtatatcttt gcttgctatt
    65821 agaaggaaaa gcaaatgagg aagtttatga gaaagatcgg attgttgttg attgccgtga
    65881 tgatgatttt accggcgatg gctcaggttt ctttcggcgt acgtgccgga ggcgcttatt
    65941 cttcgttgat ccagaaagtg gaggatacgt atgaggcggg agcccgcttc ggtttcagca
    66001 tagcgggttt ggcggatatt cctttgagta agaataaaaa atggtcgctt cgtcctgagg
    66061 tggcgttcgt aaaccaaggt ggcgcttatt attcgaatca ggatatacat gggatggcgc
    66121 ttcataataa atgttggtat tactctttgc agattcccgt gaatgtggct tatacgttta
    66181 ccttcacgga cgttcatctg tccgtattcg ccggtcctac ctttgattgg tccttgtttg
    66241 gcaagatgaa gagccgagag accaatccgg atctccattt cggcgtatcc gaggagaagg
    66301 atttgaaacc ttgcgatttt ggcatgaacg tcggcctatc ggtagaatat agtaactttt
    66361 tcttttccgt aagttcccta tgcggcatga tagaccgccg tgccttgaag cgtgacggcg
    66421 agacttccgt ttatcaaaat aacgtgacat tctctttggg gtattacttc cgtaagtgat
    66481 gagtatcttc ataataactt gaaaaataat tagatttgtt tggtatttcg gataaaaccc
    66541 gtacctttgc aagccgatta ttatcaaatt gtactaagag tttagttctt agcacgttgt
    66601 tgcatcatgt gtccgttgtg acaatgttgg taaggctagt tttttgagtt attaattaat
    66661 ttaattttta agcagtggat actttaagtt ttaagaccat ttctgcaaac aaggcaactg
    66721 taaacaaaga gtgggtcatt gttgatgctg aaggccagac gttaggtcgc ctttgcgcta
    66781 aagtagcgaa gcttttgcgc ggtaagtaca aacccaattt cactccgcac gttgactgtg
    66841 gtgataatgt aatcatcatc aatgcagaca aagtcgttct gactggtaac aagtggaacg
    66901 atcgtattta tttgagatat accggatatc ccggtggaca gatcgagtat actccggctg
    66961 atcttttgaa gaaaggtggt gaccgtctgt tccgtaaagt agtaaaaggt atgttgccta
    67021 agaaccgtct gggtgcaaag ttgttgaaca acatgtacgt ttatgaggga actgagcaca
    67081 agcacgaggc tcaacaacct aagttaatcg atataaactc atataaataa tcacgatgga
    67141 agtagtaaat gcaataggaa gacgtaaagc ggcagtcgct cgcgtattcg ttagcgaagg
    67201 tacgggaaag atcacgatca acaaacgtga gctggaaaaa tactttcctt cttcaatcct
    67261 tcagtttatc gtaaagcagc cgttagcaaa gttgaacgtc gctgagcaat atgatattaa
    67321 gatcaacctt gacggtggtg gtttcaaagg tcagtctgag gctgcccgtt tggctatctc
    67381 tcgtgcgttg ataaagatta atccggaaga taaggctgtc ttgagagcgg aaggattcgt
    67441 aactcgcgat cctcgtgctg ttgagcgtaa gaaaccgggt cgtccgaaag ctcgtaagag
    67501 attccagttc agtaaacgtt aatgttattt gtgagtccct tacaagtaaa gcgaagcgtt
    67561 tagtatctaa attatcggga ttctttttac atgtggacat gcggaaagac tacctgatgg
    67621 ttgaaattaa acaaagaaag taaacgattt aagaaaaaaa caatgtcaag agtaaatttt
    67681 gatcaattat tagaggctgg tgtacacttc ggacacttaa aaagaaagtg gaatcccgct
    67741 atggctcctt atatcttcat ggagcgcaat ggtattcata tcattgacct ttataaaaca
    67801 gttgctaaag tagacgaagc cgctgaagtt atgaagaact tggctaaaca aggcaagaaa
    67861 gttcttttcg tggctaccaa aaaacaagct aaacaagttg tcgctgataa ggctgcttcc
    67921 gtaggtatgc cttacgttat cgagcgctgg ccgggtggta tgttgaccaa cttcccgacg
    67981 atccgtaaag ctatcaagaa gatggctact atcgataaga tgacaaaaga tggtacattt
    68041 gataatcttt ctaagagaga aaaacttcaa atcactcgcc aacgcgctaa gttggagaag
    68101 actttaggtt ctatcgtaga ccttactcgt cttccgtcag cgttgttcgt tgtagacgtg
    68161 atgaaagagc atatcgctgt tcgcgaggct aaccgtttgg gtatccctgt attcggtatg
    68221 gttgatacga actctaatcc gaacaatatc gactacgtta tcccggctaa cgatgacgct
    68281 acaaagtctg tagaggttat cttgggcgct atctgcgagg ctatgaacga aggcttgcaa
    68341 gagcgtaagg ctgagaaaat tgacgcagag gctgctgagg aagctccgaa aagagagcgt
    68401 aaggcaaaag ctgctgttaa gaaagaacgt acgaagaaag aagacgacga tgcgttgaac
    68461 gctaacgttg ccggtaagtt cgcaaaagac gaagaataat tcgattgaca attgacgttg
    68521 acaattgaca attagaatac aaatacaatg ggcagttggc ttttgacagg atttgtcaat
    68581 tggcaactgt ccattgtcaa tttttgaaag tataaacatt ttaaagataa aggaaataag
    68641 attatggctg taacaatggc tgatattacc aagctgcgca aaatgagtgg agctggtatg
    68701 atggactgta agaaggcttt gacagagtct gacggtgaca tcgagaaagc aatggaaatt
    68761 atccgtaaaa aaggacaggc tatcgccgct aaacgttctg atcgtgaggc tgccgagggt
    68821 tgtgtgttgg ctaagaagga tggcgagttc gccgctatca tcgctttgaa gtgcgaaacg
    68881 gacttcgtgg ctaagaatga ggacttcgtg gctttgactc aagctatctt ggacgctgcc
    68941 gtggctaaca aatgccgtac tttggacgag gtgaaagctt tgcctatggg caagggtact
    69001 atccaagaag ctgttacgga tcgtagtggt atcactggcg agaaaatgga gttggatggc
    69061 tactgcgtag ttgaaggtgc ttacactact gtatacaacc atatgggtaa gaaccaactt
    69121 tgtacgatcg ccgctttcaa caaggagtct gaggaagccg ctcacaatat tgttatgcag
    69181 atcgccgcta tgaacccgat cgctatcgat gaggctggtg ttcctgagtc tgtaaaagag
    69241 aaagagatcc aggttgctat cgagaagacg aaggctgagc aggtacagaa ggctgtagag
    69301 gctgcattga agaaggctgg tatcaatcct tcacatgtag acagcgaggc tcacatggaa
    69361 agtaacatgg ataagggctg gattacggca gaggatgtag ctaaggctaa agaaatcatc
    69421 gctactgttt ctgctgagaa ggctgctaac ttgcctcaac agatgatcga gaatatcgct
    69481 aagggtcgtc tgggcaagtt cttgaaagag gtttgcttgt tgaaccaaga agacattatg
    69541 gatggcaaga agactgtaag agagacaatg aaggagatcg atcctgagtt acaaatcttg
    69601 gcgttcaaac gtttcacttt gcgtgctgag taattgcggt aacatatttg atataaagaa
    69661 aaaggcgata caacccaatg tatcgccttt tttatgaagt atagcttact tgcccataga
    69721 agatatactt acttgtccaa tgcagtatat cttactttgc caagtaagta tatctgttta
    69781 attttttctt atttcaatgc ggccaacgca tccttaatac gtttgatcgc ctctgcgata
    69841 ttctcatcgc tggtagcgta actcatgcgg atacactcgg gtgccccgaa agaggtacca
    69901 cctacgcaag ctacgtgcgc tacttctaag agatacatag ctaagtcatc agcgttgttg
    69961 attacacggg ttccatctgt cttgccgtaa taataactac atttggggaa taagtagaag
    70021 gcgccttccg gtttattcac ctcgaagccc ggaacttctt tcgctaaatt aacgattaag
    70081 tcacggcggc gttcgaaggc cttacgcatt tcctcaacgg gttcttgtga gcctgtataa
    70141 gccgcttccg ccgctttttg agatacggag caagggccag aggtatattg tccttgtaat
    70201 ttattaaccg ctttcacgat ccattccggt ccggcgatga aaccgatacg ccagccagtc
    70261 atcgcatacg ctttggaaac gccgtttacg ataaccgtac ggtctttcat tccttcgata
    70321 gaagcgatgc tgttgtgttt accaatatag ttaatatgtt cgtagatctc atccgctata
    70381 acgatgatat ccggatgttt tttcaatact tccgctaaac ctgccaattc ctcggcgctg
    70441 taaacagaac ccgtcgggtt ggagggagag caaaggatta acgctttagt cttaggtgta
    70501 atagcggctt ccagctgagc tggagtgatc ttgaaatctt gctcgatacc agccggaacg
    70561 ataacgggag ttccttccgc taacttcacc atctccggat agcttaccca gaaaggggca
    70621 gggatgataa cctcgtcccc cggatttacc aataccatga ccgtgttaca aacggattgt
    70681 ttggcaccgt ttgcacaaga gatctggcct gctgtatatt ccagtccatt ctcgttcttc
    70741 aatttggcaa cgatagcatt acgtaatgcc ggataacccg ctacgggaga ataacgtgag
    70801 aaattatcgt caatcgcctt cttcgcggct tctttaatga agtcgggagt attgaaatcg
    70861 ggttctccca cacttaagtt gataacatcg ataccttgag ctttcaactc accgctcttt
    70921 tgtgacatcg ccaatgttgc tgaaggcgat aaactcgcta aacgatctga gacttgtgtc
    70981 atgacattgc tttttgtata ggttgtttta ttattatgcg acaaaagtaa tcaataatcg
    71041 gaattcttgc aacgttctga taactattta atgttatgca gcacatgccc catacgttct
    71101 ttcttcgttt tcatgtagaa ttcgttgtat ggatttggtt tcacctcgat aggaacgttc
    71161 tctactacct caagtccgta tgcttccaga cctacgcgtt ttaccggatt attgctcatc
    71221 aggcgcattt tcgttacgcc gatatgacgt aagatctgtg ctccgacacc ataatctcgc
    71281 tcatccgctt gatggcctaa atgcaagttc gcgtccaccg tatccaaacc atcctcttgg
    71341 agcttgtatg ctttcatctt ctccatcaat ccgatgcctc gtccttcttg gttcaggtaa
    71401 acgataaccc ctttgccttc ttggtcgatg cggcgcatag cctcgtgcag ttgctctccg
    71461 cactcgcaac gcatggaacc gaagatatca cctgtagcgc aagatgagtg cacgcgtact
    71521 aagataggct cgtctttttc gaatttaccc tttatcaaag ctatatgctc taatccattg
    71581 cttttctggc ggaaaggaat gagacggaaa tgtccgtact cggtagggag atctacctct
    71641 acgccgttct ctacgatcga ttcggtccgg aggcgataag cgatcaggtc cttgatgcaa
    71701 ataatcttga tatcgaattt cttggctacc tcaattaatt gcggcagacg tgccatggtt
    71761 ccatcctcgt tgatgatctc gatcaaggct ccggcgggat ataaaccggc taaccgggcc
    71821 aaatccacgg cagcctctgt atgacccgca cggcgaagta cgccacggga gcgggcacgg
    71881 agcggattga tatgtccggg acgtcccaga tcggatggct tggtctttgg atcggccagc
    71941 gccaagattg tttccgcacg gtcgtacatg gaaacgccgg tcgtacattt ccctcctaat
    72001 ttatctactg ttatcgtgaa aggagtacct agtaaagagg tgttattggc aacttgcata
    72061 tccagctcca actcttggca acgttcttcc gtgatcgggg cgcataatac acctcgtccg
    72121 tttttcaaca tgaagttgat tttttccggg gttactttct cggccgcgat gataaagtct
    72181 ccttcattct cccggtcctc gtcgtctaca acgattaaga actttccttc acggaaatcc
    72241 tcgatagctt cttcgatggt gtttaattga atctcgctca tatttattga ttatttatat
    72301 ccgagttatt tttttagcaa atgtaatgaa tatatcatat tgatcagctc cttactggtc
    72361 ttttgtacca taacgatatc atgccgtagc aatttacgtt ggtacgtagc caataggtag
    72421 atcggcaatc ccagtgggaa gaaaataccg atagccaaag caagtttccc gtttatatgc
    72481 ttgcttagct tattattgta acctccgatg accgggtagt ccatcaattt attcaagagc
    72541 aaattctggt cggaattact taattcctcc acgatatttt ccgtgtcttg agctaacagt
    72601 tccgctgtgt tatcttttcc tccttgtttc caaaatgtca gataattgat ccaacgttta
    72661 tggtttgtca gataagtcgt actttcttcc accaatttct ccagttgggg gagggtggcc
    72721 tcataatcgg gggtgtatat gatcacctct ttccgttcca cttttcgccc ttcacgctta
    72781 cctattaagt tcttcaaggc attcacgtaa gtgtcggcat tcaagataac agaatctttt
    72841 accgctttat aggttaggaa tatacccata ggtgttagga ccacggagct aagccacata
    72901 ccttcccatg cgtcccaaac gccgtcgcgt gccatcttga agcccatatt atctataata
    72961 taatagaaga taaacaagat taccgagata acgaccggca cgcccaaccc tcctttacgg
    73021 atgatggctc ctaagggcgc tccgataaag aagaacatga tgcaagcgaa cgataccgtg
    73081 aatttcttat gccattccgt caagtggcgg cgtaccttat aggcctcgtc gccaaccgtg
    73141 gccgcgcgga aataatagtc ggtcttgata ttctcgatcg aggatttggc ccgacctaat
    73201 aaggcggctt ggctactcgc tgcttgcgct aggtaaagac tgtcgaaatc taactggatg
    73261 gtaggagtga ttaccggcaa tttttcctgc tgctcgtctg gttgcccctc ggcttcactc
    73321 tcttttttag cccgtaagga ctttagtgtt tttacgtatg aggcatcgta aatgcttttt
    73381 gcgttcacgt ccttgatgct atccaagcgt atgcccatcg aatcgataga ggtttgtaaa
    73441 tccttcaagt tttttcccat atattggttt tgcatgaaag attcgtcggt acggttgaaa
    73501 ttcgcgtcga attcaatcaa gatatccttg ctgctgaatg attctcgtcg ataggggacg
    73561 gcggttctcg cttgcgtcgt gttggcttgg cttttaccta cgttctcgaa agattctccg
    73621 ttgaataaag ataggacaag gaataattta tcggcggatg tctttagccg tccggagtcc
    73681 gctacgatta cacgggcgtt attgaatcct tccgaataat catagatcat cacgtctttt
    73741 aataaaccgt ccttcgggtc ctttttcttc acatatacat tgaatccggg aatatctttg
    73801 tagaatgaac cttccggaat atccaattcc ggtgatttct ggcgcatgga atataataat
    73861 gtatatagct tgacttggac aacgggcatt acgttgtttt ggaagaaaaa ggctcccacg
    73921 ctcacgaata ggagcgttac gatcaaagga cgcatgatat gtatcaatga taccccggca
    73981 gacttcatgg ccagtaattc cagacgttcc cctaaatttc caaaagtcat taatgaggct
    74041 aatagaatag ccaagggaag tgccattggg acaaggaaca aagccgcata cataaacatc
    74101 tccgctaata cagggatgcc aaggcctttt cccaccatat cgtcgatgta tcgccaaaga
    74161 aattgcatca acacaataaa cagacaaata ccgaatgtca taagaaacaa cggcaggaat
    74221 gtctgcagca taaatgtata taatcgtttt attctcaaca ttgcctaatc tggttgaagt
    74281 ggcaaaagta gtgtaaaaaa cgataacacc ccacagattt ctgtaaaact actctaaata
    74341 ccaagcgttc gcttcaaatc ttccacttgc gagtcccata aattaatgga atcttttttc
    74401 tccccgggtt cggagaaatc cgtaatctca agtgccgtag aacctgttaa ttcgattgta
    74461 tggattataa attcgaaata agcgttctca tcttcctcgt ctacccagcg gtaacggata
    74521 aagttctccg gcttggagtc gatcactgtt gcctcttggg cctctttact ccatttaaag
    74581 gtatagagat tatcatttat aatgacctcg tcggcgaacc aagcggaaag tcccaaagcg
    74641 gtggttaggt gattccacag gcttcgtcgt gaaactttat cgaaaatgta ttcgatatga
    74701 aacttctctt tcttcattgt tcttatcctt atatttgccg caagatacgt aaaagatttg
    74761 aaaacgacta attttaatga tgaaaaaagt atctaataac taactgttta ggtggagacc
    74821 ttaaaaatta agcgaatttt tttattgaaa atgttgtgta attcaaaaat aacccctact
    74881 tttgcaccgt caataagaga aacagtgaca ataaaatgat ggcgagatag ctcagctggt
    74941 tagagcgcat gattcataat catgaggtcc ccggttcaat cccgggtctc gctacctaga
    75001 aaaggaggtc gatttttcga tctccttttt ttatgtcctt ttttcttttg ctatcagatg
    75061 gtcttttggg aggataaaaa aacctgaaca atctttctcg taaacgatct tgattgttca
    75121 ggcaaaataa ttatgtaacc tcgcggttat gttaattagg tttgcctaca tcataattta
    75181 agggtaatta tatatgtaag cagggtcata gggtaaaatt tcgcaaattg ctttgcttga
    75241 tttataaata caaagatatg tatgtctaaa tgttttgagt gatggtattt gtctcaatag
    75301 gagaatgtat ttctatcata tagataacgc acgcctcgga aatcatctga agcgtgcgtt
    75361 tagcatataa aatttaaatc tagttaccct tgtttatgta gtgaccctgc tgtgattttt
    75421 atatgcttac cctaatgtct gttgcgaata tattcataat attcataggt tgtatcttta
    75481 tttgatcggt atttatatca gcttagtgtg taaaactatc aacaggtgga gtgaaccttg
    75541 tgatgaagcg ggttttcgtt agtatttaaa taaagttaag acggtgttcg tgtcaatatc
    75601 atgggtattc ctatcacgga gaatgcggtt tttgagagaa aaacagcgca cgcccgaaat
    75661 tctctaatct cgtgacgtgc gccaaagcat ataaaaattg agggtatctt aattcattgt
    75721 tatatgttgg ataacggttg cccagtcagc aattgtaata ttagccgaaa cttctccgga
    75781 gtacttgaaa gtgatctcgg tgcgttttcc gggggttgca gcgaataatt ctccattttt
    75841 gtctttttcg ctagaaaaaa taagattgcc gtccttgtaa agctctaccg ttatattttg
    75901 agccggaaaa atggcttggg tttctgttgt caaattacct ttttcgtcaa aagaagcggg
    75961 gaaagcgaat tcaacctctt ctcctgttgg gttgccattg tagtccaatg agctttttgt
    76021 atttttaatt cgatattcaa aatttccggc attactccct agatacttga tcagtccttt
    76081 tgttgaaagc tggaaaattg aagttttgcg aatgatttgt aattcgtttg atacggtgga
    76141 ttttgttgaa gagttcttat gaagcgtaac ttgtccatag aacaaatcgc tcggaatatt
    76201 agctatgccg ttattctctt ttaggctgac ttgcaaatcg gatataatat tggctttgct
    76261 catgtttgaa atctcttcgt ttccagaatt gattccactc catgcgatca cggttatgtc
    76321 attactgttc ggacagttaa tgtctatagc ccggcgagat aaaattgtag atttgtttac
    76381 attaatctgc tcgaagaaat cgttgttttg atcgaagaca aataatgtag ctccattcac
    76441 ctctcccttg gtcgtaatgt cgttaccatc tgaattcata gcttttaata ccacggagaa
    76501 tggtacttcg gcttgttcaa taacctcact tgttgttgct actacgtcat ttgaatcatc
    76561 cgtgcaagcg gagaatgaca aaactgttaa aataacagaa accgcaaata cgcaatttgc
    76621 gaaaaaatta ccccttttca tgaccctact ttttatatgc tttaccctta atctaagtga
    76681 cttggttttt ttgaccgccc ctcaacggtc tttccttatc actacatcgc aaatgtatgt
    76741 ataaaaatca taggttgtat cttttgtgat gggtattttt atcaaaaaag tgggtaaaac
    76801 tatcattata cctctatatt cctctgttga tgcatgtttc ggatgatgat taaataatgt
    76861 taatgggttt attcctgtca atttgagtgg taaatatatc atcgctggtc cttattgata
    76921 gccttgcctc tgttgtgtga taggaatgca gttgctgtta acgtctatta aaacgacagt
    76981 aaaaaacgtt cgtttaaatc ttgcgttttc atgtgcataa attatgaagt ctcattgata
    77041 atcatgttat ttttttatta tttttatcca actgaataac tgaaatttaa ataaaatttt
    77101 tgacctttgt aaggctgcaa aaaagttgaa gataaaaacg caagatttaa acgaacgttt
    77161 tttactggcg ttttatataa ataacatctt aataatcaat gatatgagat caaaaggttt
    77221 taaagcgaaa tttatgatgg cattttgggg cttgttcgtt gaagctcatt atattgctgc
    77281 gaacaatgat acaatggagg gctctcaagg aattctacct tttatcattt tactgatagt
    77341 gtccatatgt gtaatagctt ttttgagtta ttatatgtat aggttgaaga aagagaatat
    77401 tgccaaaggt ggtgagctta tggcgagaaa cgatgagctt cttcggtctg tcgatgcgtt
    77461 aagcgtaaaa aatcgggaga tccaacaaat gttggtcaat aaaatccgtg agactgataa
    77521 ttggaatagg gataatgagg tagaacggga ggatttgaaa aagcgccttg aggaaatgga
    77581 aaagctccat aattcgtttt ttgttgaaac gattcatgaa atgcgtactc cactatcgct
    77641 tgtgcttggt tcgttgagtg agttgttgca acgtaaaaat gatattgact ctagtgaagc
    77701 gactcaatta ttgtctgctt accgtaatac tttggctctt caagacctta tcgagcaatt
    77761 gcgaaatacc cgtcatggag atgacgtggc aaaccatctt cggatagctc gttatgacat
    77821 gatcagtata acaaagcaga tttgtgattt attcgtggac tggatagcca tgaataatgt
    77881 ggaatttcat attaataccc aaacctctgt tctttgggtc tggatagatc gtcggaagat
    77941 ggagtttgcc ttgcgtgtac ttttatctaa tgcgttaaaa aatacctacc gctttggaaa
    78001 gatctcgatc aatatttccg tggtacgctc gaatggtaag gcttattgtt ctttctctat
    78061 ccaagatgat gggttaggag aaagcgaaag tacccgtttg ggtttgaaac agatcgtgga
    78121 tatgacagaa tcctccggcg ctattttcga aggaatttca tcggaggacg agacgggaac
    78181 ccaatatacg atattgattc cattggggag aagccattat atggaacgtg ccgtggaatt
    78241 catcgagcca gatggtgatc tggtaaagct gaatgagatg cagaaggagg agatcgccga
    78301 gttgatccaa gttgttccga aaaagaaaga gaccgggaag aaaatgttgg tgattgatga
    78361 cagtgatcag atccgttggt tcctgcgtca tgtttttgcc agtgagtatc atgtttcgga
    78421 agctcataat ggccaggagg gtgtagagat cgcgcgagtt gaacggccgg attttatttt
    78481 atgtgacgtg atgatgcccg ttaaagatgg gcttgctacc tgtcgtgaaa tcaaaggcat
    78541 cccagaatta gcgcaagtgc cggttgtctt gctaaccgca aaggtagaga gtgaggatgt
    78601 tatagccggc attgaatgtg gcgccgatga ttatataacc aagccattcg atgtagaggt
    78661 gttacgaagt aaggtaaaca gtttattgaa acgtagggat gagatgagac gtttctatac
    78721 gtcgagtcct gtaggtgcgc atcccgaggg agagaaaacg gtaaagaaag atgattcccc
    78781 ttccaatctt tttatggatg cggttatctc aacgatcgag aaacatttgg atgaccctag
    78841 ttttgaggcg aagattttgg cggattcttt aaacatgagt ctccctacat tatatagaaa
    78901 gataaaactc tactcggata gtagtatatt ggagcttacc cgtatggtac gtttgaagaa
    78961 agccgccgag ctgatcagta tgcagcgata ctctatccaa gaggtttcgg aaatggtcgg
    79021 cttcaacgat accgccactt tccgtaagcg ttttaccgag caatatggtg tcactccttc
    79081 acagtatatg ccgggtaaga attaatcgtt ttgccatttc ccgaataatc gccggggaat
    79141 ggcaaaattt tttagttgtt ttttgatacg atatttttca acctcttttt gatagcctta
    79201 caacggtgct aatcagcccg gaaatatccc gaatgaaaat ttatagtttt acctcttatt
    79261 tatgaaagta acacctattt actttttttt atagtccaaa tacctttgcg atgtcattaa
    79321 cgaacaacag attggtcatg gggaagattt gaacaaagag ttcttgttat gtgactgaaa
    79381 atgtaaaaag tgattgagga agaaaggttt atataaaaga tttattaact cataaaatta
    79441 tatgtatatg aaacttagaa atttattatt cggaacaatg atcgcttgcg cattcgcggc
    79501 gtgttcaaac gaggatgatc ctatcgtagg accggatcaa ccgcaaacag gggaaaataa
    79561 cgcaacactg actatttctg tgaaaaatgt ggctagaagt ttgactaaag ctgcagcgga
    79621 ggggacacag actgaaaatg aagctaaaat tacaaactta acagttgctc tttatgatgc
    79681 tgaaactgga gcgcttgtcg cttcaacctc tgatattgcc aatgaggatg ctgctgcgga
    79741 taatgatgag gttcaatttg ccggactgac agaaggtgcg caattacgtg ctatcgcatt
    79801 tgctaatatg cctgaaatct cactggctgg tacaacaatt gacaactttg tatctcctgt
    79861 atatacgatg ccagctgccg gattcgcaga aaactattta ccaatgagta gtggtttgtc
    79921 tgatccattc actttacaag caggtaaaaa ctattatgga tatactaaaa cagtgggaga
    79981 aggtgaacat attcttgtag cagatccctt gtacttgata agaaatgtag cgcgcattga
    80041 ttttacggga cttagcttag acatgactag agctgcaaaa gatgtatacg ttgaaggaat
    80101 tgcgacgatt gtaccagaat gtgtattcat catgcatggg cggacgaagt ccaatgcagc
    80161 agatatgggt aatggcaata gctggtggaa tgtcgttagc aataccgtat ggggtaatgt
    80221 gtccacaact tatgctgcta atgctacaga ttatgcttca ggttatagag gagatttcgt
    80281 aaatgatgac gctatgttta cgaatatgag aggttctatt attgaaggat acaaggccag
    80341 tttaccagcc accgcattgg tacaggatat cgcaagtgaa ggtgctgcat ctgcgtctat
    80401 cacaaccgcc cctaagtttt atgtgtttga gaatccccaa gttaaggctg ctcgtgaaat
    80461 gaatggtgct gataatttca aaccagagga tcttgcaact gaaattgtag ttaaaggtac
    80521 ttataagctc gaaaatgcta aaaagagagg aagtaatgca gtatacaact atgaggagaa
    80581 aacagcctat tggcctatta aaattgctgc gacgaatgaa atggcagcag gtacggctga
    80641 ctatttaaat gatggaaaga tccatcgtaa tataatttac agtattgacg cgactttagc
    80701 tggtagagga tatgatgatc ctactgttcc tccaacagac tttgttgaat tgtttgttaa
    80761 gacaaaggtt cttgattggg gtagcgcaaa tcaatcttca gttgtcgaat aatatctatt
    80821 ctctgaataa caaccaaaag gcattccttt taccgggagt gccttttttg catatataat
    80881 tctggttata aattgatccg gagactacaa aatttactat cctttcctta tgatggcgat
    80941 cccatatgtc ttgaacctaa gaaccggaat attatttcat gagaacatct acaatatcta
    81001 caattcaacc tcatacttat tgtaaataaa tatgttatat agtggttgca gatggaataa
    81061 catctacaat tttcattctg catctaccat gttttaatgg gaaacgcaaa aaa
//
LOCUS       DBMDTB010000005        79033 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_139_length_79033_cov_12.196042, whole genome shotgun sequence.
ACCESSION   DBMDTB010000005 DBMDTB010000000
VERSION     DBMDTB010000005.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 79033)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 79033)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..79033
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_139_length_79033_cov_12.196042"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..204)
                     /locus_tag="ACZPB4_01555"
     CDS             complement(<1..204)
                     /locus_tag="ACZPB4_01555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HIR1096945.1"
                     /translation="MANSKEMTRGAVFPLLFSFTMPLLLGNLLQQTYSLIDAAIVGKF
                     LGINSLAAVGASTSVIFLILGFCN"
     gene            complement(419..2695)
                     /locus_tag="ACZPB4_01560"
     CDS             complement(419..2695)
                     /locus_tag="ACZPB4_01560"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HIR1096946.1"
                     /translation="MKTSFFKKGILAMGIACCMQLSAVENPVDYVNTLVGTQSKYELS
                     TGNTYPATAMPWGMNFWTPQTGEMGNGWTYRYDADKIRGFKQTHQPSPWMNDYGQFSI
                     MPTTEGLVFDEEKRASWFSHKGEVATPYYYKVYLADHDVTTELVPTERAAKFRFTFPE
                     TKKAYIVIDAFDKGSYIKVLPAERKIIGYSTKNTGGVPRNFKNYFVIQFDKPFTFSST
                     VKNGAIQLDESEVKTNHAGAIIGFETKAGEVVHANVASSFISTEQAELNLREVGDTGF
                     DQLVTKGKEIWNRELGKIEVEDTNIDNLRTFYSCLYRSLLFPRSFYEIDAKGQVVHYS
                     PYNGEVLPGYMFTDTGFWDTFRCLFPFLNLMYPEMNQKMQEGLVNAYKESGFLPEWAS
                     PGHRDCMVGNNSASVVADAYIKGLRGYDIETLWEALKHDANSQLPRTASGRVAYEEYN
                     KLGYVPNNIGIGQNVARTLEYAYNDWTIYTLGKKLGKPASEIDIFKQRANNYKNVYDP
                     KYKLMVGRSDKGEFNPTFKGTDWSRDFCEGNSWHWSFCVFHDPQGLIDLMGGKKEFNH
                     MMDSVFKMPSRLGMDSRGMIHEMREMQVMNMGQYAHGNQPIQHMVYLYNYSGEPWKAQ
                     YWVREIMHKLYTAEADGYCGDEDNGQTSAWYVFSALGFYTVCPGTDQYVLGTPLFKSV
                     KLHLDNGKQVLIQADKADRENRYIKGMKVNGKTYTRNFLTHEQLLGGAKIQYQMSDTP
                     NKQRGTQDSDRPYSFSLE"
     gene            complement(2710..3312)
                     /locus_tag="ACZPB4_01565"
     CDS             complement(2710..3312)
                     /locus_tag="ACZPB4_01565"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HIR1096947.1"
                     /translation="MSYQVHETAVIDAGCEIGEGTHIWHFSHIMTGCVIGRTCNIGQN
                     VVVSPGVVLGNNVKVQNNVSIYTGVICEDDVFLGPSCVFTNVTNPRSAISRKDQYKET
                     VIGKGASIGANATIICGHTVGRYAMIGAGAVVTKDVPAYALVVGNPSRQIGWVSEYGH
                     RLVFDSEGFATCPESGQRYRLHNHQVDETGHAPSHQYRQY"
     gene            complement(3323..4027)
                     /locus_tag="ACZPB4_01570"
     CDS             complement(3323..4027)
                     /locus_tag="ACZPB4_01570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HIR1096948.1"
                     /translation="MRASLFLIPVTLGDTEHRRVLPEYNRDVILSIRHFIVENVRTAR
                     RFLKKVEPGIVIDDLTFYELNKHTSPEQVAGYLAPLAKGESVGVISEAGCPAIADPGA
                     DVVAIAQRKDYPVVPLVGPSSILMSVMGSGFNGQSFAFHGYLPIDASERTNTIKKLEG
                     RIYSEHQTQLFIETPYRNNKLAEELIRTCRPSTKLCIASNITCEDEYIHTRPVKEWAG
                     KVPDLSKKPTIFLIYK"
     gene            4081..5478
                     /locus_tag="ACZPB4_01575"
     CDS             4081..5478
                     /locus_tag="ACZPB4_01575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase RsmF C-terminal domain-like
                     protein"
                     /protein_id="HIR1096949.1"
                     /translation="MALPIDFITRTRALLGEEFDRLEAALSADVPVSIRINPMKGTPA
                     PKAGAPVAWCESGFYLPERLSFTFDPLFHAGAYYVQEASSMFLEQAIKAYVKEPVRCL
                     DLCAAPGGKSTHLASLLPDGSLLVSNEVIRSRSYVLAENIAKWGHPDTIVINNDPEEI
                     GEALPHLFDVIVTDVPCSGEGMFRKDTDSTGEWSVDNVRLCASRGRRIIHDIWNALKP
                     GGILIYSTCTYNTEEDEENIHYIIEELGAEALPIPTQEEWQITGALRFEHPVYRFFPH
                     KTRGEGFFLAALRKAEGEIEEIRVKSKGKKERGKAALSIPQEARLFLSDETSFSLEWN
                     GSFLRAYPKAHSDLFSLINAKPLRVLSAGICLGEAKGKDFIPSQELALSTALTPNAFP
                     SVELEWEDAIKFLKKEALVLPSGTDKGYVLVRYQGLPLGFVKNLGNRANNLYPQEWRI
                     RTGYIPEEIKLFLGR"
     gene            complement(5595..6599)
                     /locus_tag="ACZPB4_01580"
     CDS             complement(5595..6599)
                     /locus_tag="ACZPB4_01580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4837 family protein"
                     /protein_id="HIR1096950.1"
                     /translation="MRTQTVLLWISLSLMVGLSACDWTSSSPVASLRRATGWPFEVVV
                     VMDRDAWNGEVGELLQEQLRAPIPALPQAEASMRVTYSEPSGFSGLLRYVRNILIVSV
                     DPNRYTKAGTRESPDEWASGQNVVTLYAPTTAALTEFLLLNEGRLVNHFNRVERERWI
                     VGLSKSHSSWINEKLKSRFGISLFVPEDMSAYKEETDFFWGSNNANRGRTDILVYSFP
                     YTTQEAFTEDYLVAMRDSVVKRNVPGSFPNSYMKTEQRFELSYEPITYRGEYRGVLRG
                     LWRMEGDKMGGPFVSHALLDKKKGRVIVAESFVYAPESKKANLIRRMEAALFTLRFVD
                     "
     gene            complement(6797..7480)
                     /locus_tag="ACZPB4_01585"
     CDS             complement(6797..7480)
                     /locus_tag="ACZPB4_01585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1096951.1"
                     /translation="MGEFWGFVDWGAGCLALIVAVVFSFLLGVRTGRIRERNESVRSR
                     IRQNKANMYRYKQQLASYQEQVVRLERERDSLVIRSEAYDRIETELTAYRQKMEQLER
                     EILVLSGDNNLLDNATGKVDVDVPKLLCALKDDPLHVNPSKEEWAEIIGMTDLLFNNF
                     LTDLRNKYSITRHEQEICCLIKWNFSRKEQLAVFNNTPDALTKSKGRLKKRLGLDEKT
                     DLDAYVRLL"
     gene            complement(7486..9564)
                     /locus_tag="ACZPB4_01590"
     CDS             complement(7486..9564)
                     /locus_tag="ACZPB4_01590"
                     /EC_number="2.7.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA degradosome polyphosphate kinase"
                     /protein_id="HIR1096952.1"
                     /translation="MENSYQYFKRDLSWLSFNYRVLLEAEDDTLPIYERIKFLSIYSS
                     NLEEFYEIRVAEHRGVIMKKNYSEESAAEAEETLAAITREVNRQQRDYYRIFSEKILP
                     ELNRQNVYLYQNEKPEPFHEEFVHNFFNEEVFPFLSPVMIQAGDIRTFIRDRRLYLVI
                     RMIKRSKRMNEPGFVPEYHYALMKIPYAKVPRFIELPPHDGKYYIMFIDDIIRANLQN
                     VFPGYIIDGCYSIKISRDADIYLDDESRANIVENIRKKVKKRKIGALSRFMYDQAMPD
                     DFLAFVCDAFGITSEDLVLGGRYNNLQDLMKLPNPAGKHLEQQPPVPMRVPFLDEMGS
                     VFKAVKKRDILLHFPYESFDYLIRFLMEAAFDPKVDEIKITQYRVAENSAVINTLVSA
                     AQNGKKVTVFVELKARFDEENNMSTAERMEQAGICIIYSIPGLKVHAKVAVILRKDTS
                     EGLKRRDFAYLSTGNFNEKTAKIYSDMALLTSNTEIITDINKVFAVLEGRMKEPTFRH
                     LLVARFNMVSELTGRIRREIEHVREGRKGRIILKMNGLHDQHMIEELYHASEAGVEID
                     LIVRGICCLVPNQPYSANIRVTRIVDMFLEHSRVWYFLNDGQEDLFLTSADWMRRNLN
                     RRIETAFPILDPDLKREIIDILNIQLSDNVKACYLDGELRNNFKCDDNPVKVRSQLAI
                     YDYLRNKSIR"
     gene            9623..10123
                     /locus_tag="ACZPB4_01595"
     CDS             9623..10123
                     /locus_tag="ACZPB4_01595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HIR1096953.1"
                     /translation="MIKVGLLSDTHAYWDDKYAEYFKDCDEIWHAGDIGSDLLAAKFE
                     ALKPFKAVYGNIDGQAIRLQYPKVAHFKVEDVNVMMTHIGGYPGRYNPEIRKELYDTR
                     PNLFISGHSHILKVVFDRSLKCLHMNPGAAGKSGFHQVRTLLRFVIEGKDIKDLEVIE
                     LGNRAL"
     gene            complement(10129..11247)
                     /locus_tag="ACZPB4_01600"
     CDS             complement(10129..11247)
                     /locus_tag="ACZPB4_01600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1096954.1"
                     /translation="MNRVKKGLDNQAIGLLPLLLFMFLDNYFSYLLSFIIGVTFCFVC
                     IFLFQVLSKDKVYQFMLLPSAGTLVLYSVFLCLKLEPVLFIYSPLITEVLLVVALAIV
                     GFTRRTVIQRIRDSKRPSFKRTLLRTTLNEFYFLAQLVQNLYTLHLFIILLYSILPET
                     MQNMRTERFLYRELGLVIGVLVIVYEQIRLSLMQGSLKKEMWVPVLNDNGKVIGCIAR
                     SVSRSLPKKYYHPIVRIAVVYNGMLYLVRRSKDEFVSPDTMDYPFHNYVLFRHSIDST
                     VKETLGSLAQDKSIAPRFLIRYTFENEKVKHLVSLYVICLRTEEQLNQCKRRSGKLWT
                     AKQIEENLSSGVFSEYFEKEFAYLQNTILFAESFCCGN"
     gene            complement(11311..12156)
                     /gene="lipA"
                     /locus_tag="ACZPB4_01605"
     CDS             complement(11311..12156)
                     /gene="lipA"
                     /locus_tag="ACZPB4_01605"
                     /EC_number="2.8.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016992 - lipoate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0009107 - lipoate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoyl synthase"
                     /protein_id="HIR1096955.1"
                     /translation="MAQHLRKPDWLKIRLGGNEQFTKTKSIVESHCLHTICTSGKCPN
                     MGECWSRGTATFMIGGEICTRSCRFCNTLTGKPLPLDPKEPANVAESIRLMNLKHAVI
                     TSVDRDDLPDLGASHWVNTIRTIKEVNPQTTVEVLIPDFQGRLDLVDQVVDAAPEIIS
                     HNMETVRRISPQVRSAAKYDVSLSVLRRIAERGVVAKTGIMVGLGETEDEVLELMDDV
                     LQAGVSVLTIGQYLQPSRKNIPVSEYVTPERFEYYRQQAVNKGFKKVESAPLVRSSYH
                     AEKHI"
     gene            complement(12160..14334)
                     /locus_tag="ACZPB4_01610"
     CDS             complement(12160..14334)
                     /locus_tag="ACZPB4_01610"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HIR1096956.1"
                     /translation="MKRLGFSLLLSLAVFGSVAAQTGSKHVDLKEITDGKFRQVTAIG
                     EMRSLPDGEHYTAMNADKSMIIKYSYRTGNPVDTLFNARKARECTFTDFDGYTISSTG
                     HHILVWRDTESIYRRSTKAVVYDYDVRRNYVKPISDAKGKQMIPTFSPDGRMCAYVRD
                     NNIWIRKFDFDTEVQVTKDGELNKILNGITDWVYEEEFAVTNLMAWSPDSEYLAFVRF
                     DESEVPEYSMQMYGEGLYPGYYEYKYPKAGQKNSKVSVHSYSVVTKDTKEMKVPVEGD
                     FYIPRITFTQNPDQLAIMTLNRQQNVFNMYYANPKSGVFRLILREENKCYVDSDWLTS
                     IQFLNNGFTYVSEQDGYSHIYLYSPTGVMQRQVTQGNWDVTKFLGVDENTKTFYYESA
                     EESPIRRSIYKIDAKGVKTKLSTDEGMNKAVFSDNFAYFVNTYSNANTPAKITVNETK
                     TKKELRVLQDNAALKSKLKEYAFAKKEFMKVHTASDYEFNAWIVKPADFDPSKKYPVM
                     MTQYSGPNSQQVLDQYGFDWEQYLASNGIIVVCVDGRGTGARGEAFRKCTYLRMGELE
                     SRDQVEAAQALGKLPYIDKDRIAIWGWSFGGYNTLMALSTGNGTFKVGIAVAPPTDWK
                     YYDSVYTERFMRTPQENFEGYAATSPLRRVKDLQGKLLLVHGTADDNVHFMQTMEYAE
                     ALVQANKQFDMHVYKDRNHSIYGGNTRYHLYTKMANYLFNNL"
     gene            14415..15341
                     /gene="mnmL"
                     /locus_tag="ACZPB4_01615"
                     /gene_synonym="ytqA"
     CDS             14415..15341
                     /gene="mnmL"
                     /locus_tag="ACZPB4_01615"
                     /gene_synonym="ytqA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018032.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA modification radical SAM protein MnmL/YtqA"
                     /protein_id="HIR1096957.1"
                     /translation="MKKTKRYYEFGDFLRDLFKFKVQKISINAGFTCPNRDGSKGWGG
                     CTYCNNQTFSPEYCHTEKSVTEQLEEGVRFFSRKYPDMRYLAYFQAYTNTYDRLDSLI
                     LKYEEALAYPGVEGLIVGTRPDCMPEGLLDYFAELSQRKFVMIEYGLESTLDKTLVRI
                     NRGHTHEESESAIRRTAAKGIYTGAHLILGLPGESRDETLHHADVLSRLPITTLKLHQ
                     LQLIKNTRMAKEFKEDPSDFHLYTADEYIELVIDFIERLNPSIVVERFVSQSPKELLI
                     APDWGLKNFEFTAKVNKRIEERDTRQGRLFQV"
     gene            complement(15327..15821)
                     /locus_tag="ACZPB4_01620"
     CDS             complement(15327..15821)
                     /locus_tag="ACZPB4_01620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4251 domain-containing protein"
                     /protein_id="HIR1096958.1"
                     /translation="MRLTRLVGFLGIVLFCAGQSLFAQSKQERKEQKERVVREIVDSG
                     RIKIDVDRAVPMAGRSVNLTSPYSLEIHGDSILSYLPYFGRAYSAPYGGGEGLTFKEV
                     AAEKEQTSEKKGSSEIKFRVKTKEDVYMFRVEVYPNGSVTINVTPVNKQAITFYGDVA
                     LDLK"
     gene            complement(15936..16910)
                     /locus_tag="ACZPB4_01625"
     CDS             complement(15936..16910)
                     /locus_tag="ACZPB4_01625"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase family protein"
                     /protein_id="HIR1096959.1"
                     /translation="MNRNWVYSLFALWIVCSFACTQPKPVANVEVQKENFVFSIKGTD
                     TLSLDKYELPSISPASKKPVMIFAFGGGFKGGDKADKGYIPYFEFLARNGFVVVSTDY
                     RTTLKNLDPSKVSSPMDFIAALQHAIDTAVEDFYDATGFVINQSSDWNIDVEQIVASG
                     SSAGAITVLQAEYDLCNGHELAKRLPAGFNYAGVISYAGAVSGVLPPHWEKMPCPIML
                     FHGDADKTVPFEQAAMENLGGLWGSSAVAKSLENLQASYYFYKVENAGHEISGLPMSR
                     NQYDIMSFLGRQVLGDENLAITTDERVPGDTIVRKDFTVQDYILDNLR"
     gene            complement(16930..17265)
                     /locus_tag="ACZPB4_01630"
     CDS             complement(16930..17265)
                     /locus_tag="ACZPB4_01630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6565 domain-containing protein"
                     /protein_id="HIR1096960.1"
                     /translation="MKKVLFMLLVMFALSACQSKDSYVKEFSDFVDKVEMEAADYTDK
                     DWKKADLKFSDLSTNLYAKFEEELNADEKAEIIKLQATYAGLKMKAGVKDAAKKVDKF
                     LDGLKEGTK"
     gene            17388..20066
                     /locus_tag="ACZPB4_01635"
     CDS             17388..20066
                     /locus_tag="ACZPB4_01635"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005388 - P-type calcium transporter
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006816 - calcium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HIR1096961.1"
                     /translation="MEKKHQYRGLTKQEVEESRRLHGENVLTPPQKASLWSQFLEKFE
                     DPIIRILLVAWLLSMIIAGVHCWGPEAKGFTAFLEPIGIFFAIMLASCVGFFFEVKAN
                     KAFDILNTVNDDILVKVIRDGNICQIPKKEVVVGDIVVLETGEEIPADGHLLEAISLQ
                     INESTLTGEPIISKTTNEADFDTEATYPSNVVMRGTTVVDGHGVMQVEKVGDATGYGK
                     VYEGSQIESDVETPLQIQLKGLAGVISKAGYTIAGVTFIALTVKFLLSDSFPGMPAMD
                     IIAHILNYFMVAVTLIVVSVPEGLPMSVTLSLALSMNRMLKTNNLVRKMHACETMGAT
                     TVICTDKTGTLTQNQMQVYQTNFYNLKEQKLGEDELSNLIKEGISTNSTAFLDFSEEK
                     VKTLGNPTEAALLLWLNGQHQNYLELRENATILDQLTFSTERKYMATIVQSPLLGKKV
                     LYVKGAPEIVLAKSNRVAIDGTCKPVAECKAGIEKQLLDYQNQAMRTLGFAYQIIEDG
                     KDETFFVEGRLHDTDLTYLGIVAISDPVRADVPPAVQSCLNAGINVKIVTGDTPGTAK
                     EIGRQIGTWKTDDSDRNIITGPAFEALSDQEALERVLDLKIMCRARPTDKQRLVQLLQ
                     QKGAVVAVTGDGTNDAPALKAAQVGLSMGDGTSVAKEASDITIIDNSFSSITRAVMWG
                     RSLYRNIQKFLLFQLTINVAACLIVLLGSLLGTESPLTITQMLWVNLIMDTFAAGALA
                     SLPPNERVMKDKPRRSGKDGDFIITRPMAYNIFGVGFAFVVILMGLLFYFHAQDGLTP
                     HDLSWFFSFFVMLQFWNMFNAKAFMEGRSAFANLKDSKSFLLVALLILIGQYLIVTFG
                     GEMFSVIPLSLRDWVIIIGSSSLVLWIGELFRLSKR"
     gene            20215..20802
                     /locus_tag="ACZPB4_01640"
     CDS             20215..20802
                     /locus_tag="ACZPB4_01640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase family protein"
                     /protein_id="HIR1096962.1"
                     /translation="MEHLLELAKRNQERAWEVIRQTDIINIWKSVGAEINLVGSLNMG
                     LLMKHKDIDFHIYTSPFRISDSFQAMARLAENPLIKRIEYGNSLDTEERCVEWHAWFQ
                     DPNNELWQIDMIHIVKGSRYDGYFEKMAERITAVLTDETRQAILKLKYETPDTAKIMG
                     VEYYQAVIQDGVRTYAELEDWKKQHPVTGVIEWIP"
     gene            complement(20808..22922)
                     /locus_tag="ACZPB4_01645"
     CDS             complement(20808..22922)
                     /locus_tag="ACZPB4_01645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane beta-barrel protein"
                     /protein_id="HIR1096963.1"
                     /translation="MKTAIVPFLLLLNVLVAVNAQTKDSVILVKDSITVKLPDVYVTS
                     ERPLVTVTDDALSFDVPNLIMAKPVNTAFDILGEIPGLVKEGDNVSIIGIPATNIIIN
                     GRRSSMSLSQIVELLKSTSASKVKSIELLYSSPPKYGVKGGSINIIMEKKVNEDLSAD
                     ISLTGKQAFYFSPTGLVNLSYSKKKYSLDLSYSARYNHSLSTEDMNAYPIVKDRPYEI
                     LQENTAVGRSMNHTIGASASWFMDKGREVDISYYAKITDSNSKRYSNTLFVGIENAES
                     NNKLSGPKNLQNVRLNYAHSKNLNAGVDYTYYKDRRDQYMISDYPDTKQEVEATSRQN
                     IHLANVFVNYERVFGKGWKINVGTNVQLSFTDNSSITYQDKQEDLSATFAQKEKEYTA
                     GLYAGFSKRFGKKLVLSASLSAEYNKAVIDSAGRKWALWSGANLYPQLNLSYTIDPSN
                     MLQVNFSSDKKYPAYWAMSSNVSYLNVYSQVRGNPYLEPERIYMARANYILKKKYVFG
                     LFANHHVNYIRQLYYQDTKALRAYYQSVNFDKHNTFGAMAVIPFRIGGVVSSRFVASG
                     FLIQEEGVFIDISFDRKKLFGQLMLFNTFTLSKKKNLSLEVNARYSAPSVQGIYDVDG
                     NYNVSAGLIWNPIPKKLSVMLRGEDLLKGLRAKTHIDYPSQKSDMTIYSDTRSVSLTL
                     KYTLGKMNRKNKKEIDSSRFGQ"
     gene            complement(23145..23660)
                     /locus_tag="ACZPB4_01650"
     CDS             complement(23145..23660)
                     /locus_tag="ACZPB4_01650"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HIR1096964.1"
                     /translation="MKALSMYVWSLLVIMMMGLTSCGDDDELQFSEEQLAYINKNKEY
                     IWEKKTEKDEMGELRYKQVVLGGDTALYRIIRKENEWTTTPTMTSVVYLLGLEGKFID
                     GQVFQKKLDRSSFSMNGIIPGLSGVLLNIHLDETVEAIIPASLGYGYGDYSGIPGGST
                     LIFTFTLDKVE"
     gene            23790..26024
                     /locus_tag="ACZPB4_01655"
     CDS             23790..26024
                     /locus_tag="ACZPB4_01655"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HIR1096965.1"
                     /translation="MKLNKLIAIATISLLSGGISMAQKALNLEDIVAGNVIQTKGIGS
                     MTWLKDGERYSRLENNKQTGGTDIVAYQAKDNSREVIIPSSLLTDKSTGKPIPARSIS
                     WSADNKKVLIYNNTQRVWRYDTRGDYWVLNLKDGALRQLGKGMPESSMMFAKFSPDGT
                     RVAYVSNNNIYVEDIDSGKITQLTKDGSDTIVNGTFDWVYEEEFSCRDGFRWSPDGKH
                     IAYWQSDTKGTGVFDIINNVDSIYAKVIHFPYPKAGTTNSAVKVGYVSSTGGNTTWIA
                     IPGDPRNNYLPRMEFIPESDELFIQQLNRPQNTNKVWIAKISDNSLNNIFTDTDAAWL
                     DTNDNIQWLKDNRYFTWESERSGWRHLYRISRDGKEIQPITKGDFDYISPVGTDLQKG
                     WVYFIASPDNFTQRYLYRAKAFGNGEVERVSPMEQSGQHRYNMSPTGKWAIHTYSNAS
                     TPSVIDMVSFPKHQSVRMLEDNAQAKDQYAALGLNPKEFIKVKSGNLTLDAWMIKPVD
                     FDASKKYPVIIEVYGEPASATVQDVWGNGDLWQQYMANQGYIVVSIENRGANTPRGRE
                     WRKCIYGEVGTFASEDQSRGILDMTRQYPFIDANRIGITGWSGGGSQTLNCMFRYPKI
                     FHTGIAIAFVADQRLYDTIYQERYMNTPQNNPEGYHKGSPITYAEGLEGNLLLIHGTG
                     DDNVHYQNCEMLVNKLIKNGKMFTQISYPMRSHSINEREGTTLHLRKTMAKYWLEHLP
                     AGGK"
     gene            26040..27899
                     /locus_tag="ACZPB4_01660"
     CDS             26040..27899
                     /locus_tag="ACZPB4_01660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HIR1096966.1"
                     /translation="MKQFLLRLVILAGISFLPTVSNAQLREKAEELLSTTLGNDPEEP
                     VTPTDTLSLDEQHRKDSIKMQELALQLQEMKLNEILLKDELESTKNSNATADSLKRSE
                     QRNRIDSLRALTPGVPVVVEGDTLFHLYAKRGGRTPVDRAEDILNIMVKIGTSHSLKK
                     DSIYIYDSEYVTDIMYGDKVILSITDQDALWQNLSRIALAEQYQPIIQNKIQELREQH
                     SILQIAKRVLLFILVIIIQYFLFKLTNYLFKKLRRKIIWLKQNRLRSITIRDYEFLNT
                     HRQGRVLMFFTNVIRWIVLLIQLTISVPILFAIFPQTEDLALKIFSYLLEPVKMIFKS
                     VASYIPNLFIILVIYYCIKYIVKGIQYIANEIESENLKISGFYPDWAQPTFNIIRFLL
                     YAFMIAMIYPYLPGSDSGVFQGISVFVGLIISLGSSTVIGNIIAGLVITYMRPFKLGD
                     RIQLNETTGNVIEKTPFVTRLRTPKNEVVTIPNSFIMSSHTTNYSVSARQYGLIIHST
                     VTIGYDVPWRQVHQLLINAARQTTGVLPEPKPFVLETELSDYYPCYQINAYIKDADKL
                     GDIYSDLHQNIQDVFNEAGVEIMSPHYFAGRDGSASTIPTAPYPDDWVEPSKK"
     gene            28000..28608
                     /locus_tag="ACZPB4_01665"
     CDS             28000..28608
                     /locus_tag="ACZPB4_01665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper resistance protein NlpE"
                     /protein_id="HIR1096967.1"
                     /translation="MKKYFIAVAAMAFLAACSGKQAQKDVPVEVEEEEFAIMSAAPDA
                     PSLPLIHSVKATQPAKPVNMRDSLKADPKKGPVIQKKYKGTLTSPDSVNVDYDLTLYY
                     QQDNADEEGVFELDALYTVPEAVASSTGAAKKAPQKAITTGKQKVKHGTPDDASAVIY
                     ELIPSDGEPVIYFLVEGDNLTLMNDALQKAAADLNYTLRLVQ"
     gene            complement(28717..29934)
                     /locus_tag="ACZPB4_01670"
     CDS             complement(28717..29934)
                     /locus_tag="ACZPB4_01670"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HIR1096968.1"
                     /translation="MKKTILVSSMLFALTMSATIQAQDTEKKVSEEGFVFTTVKENPI
                     TSVKNQNRAGTCWCYSSYSFLESELLRMGKGEYDLSEMFTVYNTYLDRADAAVRTHGD
                     VSFSQGGSFYDALYGMETFGLVPEEEMRPGMMYADTLSNHTELSALTDAMVAAIAKGK
                     LRKLQSDENNAMLWKKAVAAVHQIYLGVPPEKFTYKGKEYTPKSFFESTGLKASDYVS
                     LTSYTHHPFYTQFPLEIQDNWRHGMSYNLPLDEFMEVFDNAINTGYTIAWGSDVSESG
                     FTRDGVAVMPDDEKVQELSGSDMAHWLKLKPEEKKLNTKPQPQKWCTQAERQLAYDNY
                     ETTDDHGMQIYGIAKDQEGNEYYMVKNSWGTNSKYNGIWYASKAFVRYKTMNIVVHKD
                     ALPKAIKAKLGIK"
     gene            30089..30892
                     /gene="proC"
                     /locus_tag="ACZPB4_01675"
     CDS             30089..30892
                     /gene="proC"
                     /locus_tag="ACZPB4_01675"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0055129 - L-proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HIR1096969.1"
                     /translation="MRISIIGSGNIGGAIARGLAKGTMFKASDITCTAQSDETLEKMR
                     KIDPDFILTHDNVEAARNADIIIIAVKPWRVEMIIDEIKSVLDFEKQIIVSVAAGVTF
                     DLLNTYLTKNTDFDCLATPTIFRIMPNTAIEVMSSMTFVSARNASKEQTDLIIHIFNE
                     LGNAMLVEERLMGAGTALASSGIAFALRYIRAAIEGGVELGFYPKQAQEIVVHTVKGA
                     VDLLLENKSNPEMEIDKVTTPGGITIKGLNEMELSGFTSSVIRGLKASK"
     gene            complement(30955..32142)
                     /locus_tag="ACZPB4_01680"
     CDS             complement(30955..32142)
                     /locus_tag="ACZPB4_01680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline dehydrogenase family protein"
                     /protein_id="HIR1096970.1"
                     /translation="MLDFNNTEIAFSSKSRGELQNAYWLFNTIKYPWLVKCAKVATSI
                     ALKIHFPLAWAVKPTLYKQFVGGETLQDCSAAINHLMKYNVKSTLDYSAESEQTPEGI
                     QATFEETLRSIDFAKGNTNLAYAVFKPSTITTDELLAKASEKREELTIDDVRHFREFR
                     ERFMALCQRAYDNDVRILVDAEDYCFQDAIDALTDEAMRKFNKKRAIVFATLQMYRHD
                     RMPYLRRIYDDAVAKGYIAGVKFVRGAYMEAERARAAALDYPDPICKDKQATDENYDA
                     AVRFTMDHLDRFEMFMGTHNEESNYKLAKLMDEKGIARDDSRVFFAQLLGMSDNISFN
                     LAHAGYNVTKYVPYASVRDVLPYLIRRAEENTSVAGQTSRELRMLEMEMTRRKEHKPA
                     EGR"
     gene            complement(32233..33864)
                     /gene="pruA"
                     /locus_tag="ACZPB4_01685"
     CDS             complement(32233..33864)
                     /gene="pruA"
                     /locus_tag="ACZPB4_01685"
                     /EC_number="1.2.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003842 - L-glutamate gamma-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_process: GO:0010133 - L-proline catabolic process to
                     L-glutamate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-glutamate gamma-semialdehyde dehydrogenase"
                     /protein_id="HIR1096971.1"
                     /translation="MDNAIFRFPKPINEPVKAYAPGSSEKASLKKALAQISSEEWDIP
                     LVIGGKEIRTGNTGKVVMPHDHHHVLATYHKAGEKEVQMAIDAAMKAHKEWSELPWVE
                     RASIMLRVAELLATKYRYILNASVMLGQSKNPFQAEIDAPCELIDFLRFSTFYASQVY
                     ADQPYSETGILNRMEYRALEGFVFSLTPFNFTSIASNLNMAPAMMGNVAVWKPSTTAI
                     HSNYFLMKVFQEAGLPDGVVNFIPGQGSVIGKVITGSRDLAGFHFTGSTSTFNTLWRQ
                     IGENLGHYKSYPKIVGETGGKNFIFAHPSAPALDVATAIVRGAFEYQGQKCSAGSRAY
                     IPASLWKELKDYVGDMLKEIKMGDVQDFTNFVNAVIDEASFDNIMSYIDYAKQSPDAE
                     VLFGGNGDKSVGYFVEPTVIQTTDPMFKSMVEEIFGPVITIYVYDDAKYEETLELCDR
                     TSPYGLTGSIFARDRYAIDKAFNTLRYSAGNFYINDKPTGAVIAQQPFGGSRASGTND
                     KAGGPLNLIRWTNPRCIKECLVPPTSYGYPFLGEK"
     gene            34081..34269
                     /locus_tag="ACZPB4_01690"
     CDS             34081..34269
                     /locus_tag="ACZPB4_01690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005637036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HIR1096972.1"
                     /translation="MAIKRVWIEEDCIACGTCEGICPEVFTVTDRSRVNEGVNFDDFE
                     AGIKEAAESCPVEVIKYE"
     gene            34423..35076
                     /locus_tag="ACZPB4_01695"
     CDS             34423..35076
                     /locus_tag="ACZPB4_01695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1349 domain-containing protein"
                     /protein_id="HIR1096973.1"
                     /translation="MRKLVLLSFVIVASLQFCGAQSLDKMQWFNEPEQWEIKDKSLSM
                     QVTPQSDYWRISHYGFTVDDAPFYYATYGGEFEVKVKITGDYKQRFDQAGLMLRINHE
                     NYIKAGIEFVDGKYNLSAVVTHKTSDWSVITLDKAIPYVWIKAVRRLDAVEIFYSFDD
                     KEYTLMRNAWLQDNIPVQVGFMAACPDGKGFNVTFEHFKVKHLPDQRRLEWLKKNAE"
     gene            35775..36329
                     /locus_tag="ACZPB4_01700"
     CDS             35775..36329
                     /locus_tag="ACZPB4_01700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008152349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIR1096974.1"
                     /translation="MNEQIQQIAERLAGLRDALEITPEEMAKVCNLTTEQYLLLESGT
                     VDISVSVLHQISQAYGVELTTLMFGDEPKMSTYFITRNGKGVAVERTKAYKYQSLAAG
                     FVGRKADPFLVTVHPKPEDEPMYLNSHPGQEYNMVLKGRLLLQINNKDLILEEGDSIY
                     FNSELPHGMKALDGEKVSFLAVIL"
     gene            36342..37997
                     /locus_tag="ACZPB4_01705"
     CDS             36342..37997
                     /locus_tag="ACZPB4_01705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005778892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HIR1096975.1"
                     /translation="MLERFIDKTTFESQEDFIKNFKIKVPENFNFGYDVVDAWAEEEP
                     DKKALCWTNDHGEHIDFTFADLKRYTDQTASYFQSLGIGHGDMVMLILKRRYEFWFSI
                     IALHKLGAVVIPATHLLTKKDIVYRANAADIKMIVCAGEEVITKHIIEALPDSPTVKS
                     VVSVGPEIPEGFEDFQQGIQNAAPFVRPSHPNSNDDISLMYFTSGTTGNPKMVAHDFT
                     YPLGHIVTGSFWHNLHKDSLHLTIADTGWGKAVWGKLYGQWIAGATVFVYDHEKFTPA
                     DMLQMIQDYRITSLCAPPTIFRFLIREDMTKYDLSSLQYCTIAGEALNPAVFDTFYKL
                     TGIKLMEGFGQTETTLTVATFPWMEPKPGSMGVPNPQYDVDLLRPDGSRAEDGEQGQI
                     VIHTTNGKPIGLFKEYYRDAERTREAWHDGLYYTGDVAWRDEDGYLWFVGRADDVIKS
                     SGYRIGPFEVESALMTHPAVVECAITGVPDEIRGQVVKATIVLAKDYKDKAGDALVKE
                     LQNHVKRVTAPYKYPRVVEFVDELPKTISGKIRRVEIRDKDNK"
     gene            38013..39086
                     /gene="proB"
                     /locus_tag="ACZPB4_01710"
     CDS             38013..39086
                     /gene="proB"
                     /locus_tag="ACZPB4_01710"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA];
                     GO_process: GO:0055129 - L-proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HIR1096976.1"
                     /translation="MKRIAVKIGSNVLTRKDGTLDITRMSALVDQVADLHRQGMEIVL
                     ISSGAVASGRSEIKAGKKLDPVSARQLYSAVGQAKLINRYYELFREHGMTCGQVLTTK
                     ENFGSRTHYLNQKHCMEVMLENKVIPIVNENDTISVTELMFTDNDELSGLIATMMGMD
                     ALVILSNIDGIYNGNPSDPDSSVIREIECGKTDLSEYVQTSKSSFGRGGMLTKCHIAQ
                     KVADEGIAVIIANGKKDNILPMLLAVDSDTVCTRFIPASKPVSSVKKWIAHSEGFAKG
                     EIHINKGAEEALTAPKATSVLLVGVTRIEGDFEKDDIVKIMNEEGVQIGVGCTAYDSE
                     EARKQIGQRDLKPLIHYDYLYLD"
     gene            39092..40339
                     /locus_tag="ACZPB4_01715"
     CDS             39092..40339
                     /locus_tag="ACZPB4_01715"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_process: GO:0055129 - L-proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HIR1096977.1"
                     /translation="MNVKDMLRQASDAAKQLITLSDQTIIGILKETAQVLRTHTEEVL
                     AANRQDLERMDPANPKYDRLKLTEERLQGIAADMENVSTLPSPLNKVLSETIRPNGMV
                     IRKVTVPFGVIGVIYEARPNVTFDVFSLCFRSGNVCVLKGGSDADFSNRALVRIIHSV
                     LERQGINPAVCTLLPPDREATAELLGAVGLVDLIIPRGSSSLIHFVREHAKVPVIETG
                     AGICHTYFDRSGDKGKGREIVNNAKTRRVSVCNALDCLIIHRERLSDLPYICGKLPDS
                     NVIIYADEPAYAALSEHYPETLLQHANEKSFGTEFLDYKMSIRTVSSLDEALSHIARY
                     SSKHSESIISEDPETIRRFQQLVDAACVYANVSTAFTDGAQFGFGAEIGISTQKLHAR
                     GPMALPELTTYKYIIEGDGQTRI"
     gene            40390..41865
                     /locus_tag="ACZPB4_01720"
     CDS             40390..41865
                     /locus_tag="ACZPB4_01720"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1096978.1"
                     /translation="MSTVIDSNIFNTLVSNTFYSCPLGGAIYDTEGNLIDLNKAMFAH
                     FSLADKHDFIIEHLFNNIVLTDSLKSSLRKGDAIICEEPVTFKVEPIYTDEQGLSGYT
                     LWLTQQGEKETDRENKLLMGQLNESRILMRQALEDGKLAAYSFSFDRFSTCDKKHCNR
                     CFQFYGTTNTLLDKNRFICRALSSVRKPEDSLDFFYLFNKIRDEKLSSHNVTFHLRNQ
                     DGTYKMYEISGKSMDIDESGTPHVIIGSIIEKENDELAIADHQKSKDLSLLKSTFLAN
                     MTHEIRTPLNAIVGFSDMLGLEDDPEMREQYISMIKENNTALLELINDTLEMSRIESN
                     TINWSYEDVNPLAIMHDVYEYASPRISENVRLILDDSPNVSLHTDKHKLMLILKKLLS
                     NAPRYTEKGEIHFGYQSLYPVSVQFYVSDTGNGIPKDKLGHIFERFVQLNEFQPGTGL
                     GLSICKGLVTAMGGTIWVNSEEGKGSTFSFKLPITPPDTIS"
     gene            41945..42907
                     /locus_tag="ACZPB4_01725"
     CDS             41945..42907
                     /locus_tag="ACZPB4_01725"
                     /EC_number="2.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016597 - amino acid binding [Evidence
                     IEA];
                     GO_function: GO:0043857 - N-acetylornithine
                     carbamoyltransferase activity [Evidence IEA];
                     GO_process: GO:0042450 - L-arginine biosynthetic process
                     via ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylornithine carbamoyltransferase"
                     /protein_id="HIR1096979.1"
                     /translation="MRHFTCVQDLGDLKQALNEAFEIKKDRFQFSELGKNKTLLMIFF
                     NSSLRTRLSTQKAAMNLGMNTIVLDVNQGAWKLETERGVIMDGDKPEHLLEAVPVMGC
                     YCDVIGVRSFARFENKEDDYNEKILSQFIEHSDRPVFSMEAATRHPLQSFADLITIEE
                     YKKTARPKVVMTWAPHPKSLPQAVPNSFAEWMNATDYEFVITHPEGYELDPRFVGNAK
                     VEYDQKKAFEGADFIYAKNWSAYKDPNYGQVISTDRSWTVDAEKMVLTNNAYFMHCLP
                     VRRNMIVTDDVIESPQSIVIPEAANREISAQTVLKKILMGLSNL"
     gene            complement(43107..43421)
                     /locus_tag="ACZPB4_01730"
     CDS             complement(43107..43421)
                     /locus_tag="ACZPB4_01730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3467 domain-containing protein"
                     /protein_id="HIR1096980.1"
                     /translation="MENNKPANNEIQIELSEEMAQGTYANLAIISHSSSEFILDFIRV
                     VPGAPKAQVKSRVILTPDNAQRLLFALQDNIKKFGEQLQAGNNNNKTANFEDFAGPTG
                     EA"
     gene            complement(43784..44668)
                     /locus_tag="ACZPB4_01735"
     CDS             complement(43784..44668)
                     /locus_tag="ACZPB4_01735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HIR1096981.1"
                     /translation="MGKVDVLKETTPLSSEDCFLVMQRPKSGFNFPLHVHMEFELNYL
                     ENAAGAIRIVGDSVEEIDDLDLVLIAGGTKHAYSNHKCPCNGIFEITIQFHKSLFDSL
                     INRRHFKTMKDMFDNASSGLVFSREMILGIQDKLRMLSNDNKPDSFKNLLRLVEILKI
                     LSLDKAARRLNAVNTVKNYNNNDTDRLDSIMLYLHENYQKRITLSEVAKLTNMSDASL
                     MRFLKKWTGKTFIDNLNEIRVAEAVCRLTDTSDSISEICYRCGFNNLSNFNRVFKRRR
                     GSTPTEYREKYSRSRFII"
     gene            complement(44684..45547)
                     /locus_tag="ACZPB4_01740"
     CDS             complement(44684..45547)
                     /locus_tag="ACZPB4_01740"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HIR1096982.1"
                     /translation="MKRILLCLMVALFATGCLFAKNNDEKMNVMSYNIRYDNSGDKDN
                     QWKFRRDFAADLVKFYEADVFGAQEVLNNQLNDLLNRLPEYAYVGVGREDGKTKGEYA
                     PIFYRKDRFSVDKSGNFWLAEDINAIGKKGWDAACERVATWAILKDKNTGKKFFFLNT
                     HLDHMGKVARHEGASLVLEQAKKLSENLPIIVTGDFNAVPSDEPIQVLTNPSDPRHLT
                     HSRTIAGFIYGPEWTFHDFGKIPYDKREWIDYIFVKGNIKVLRHGVLTETLNNLFPSD
                     HCPVISTLILE"
     gene            complement(45708..50003)
                     /gene="rpoC"
                     /locus_tag="ACZPB4_01745"
     CDS             complement(45708..50003)
                     /gene="rpoC"
                     /locus_tag="ACZPB4_01745"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed RNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HIR1096983.1"
                     /translation="MAFRKENKIKSNFSKITIGLASPEEILENSSGEVLKPETINYRT
                     YKPERDGLFCERIFGPIKDYECHCGKYKRIRYKGIVCDRCGVEVTEKKVRRERMGHIH
                     LVVPVAHIWYFRSLPNKIGYLLGLPTKKLDSIIYYERYVVIQPGCVDTVGELDLLSEE
                     EYLDILDSLPRENQLLEDTDPNKFIAKIGAEAVYDLLARLDLDSLSYELRHRANTDTS
                     QQRKNEALKRLQVVESFRASRGRNKPEWMIMKVIPVIPPELRPLVPLDGGRFATSDLN
                     DLYRRVIIRNNRLKRLIDIKAPEVILRNEKRMLQEAVDSLFDNSRKSSAVKTDANRPL
                     KSLSDSLKGKQGRFRQNLLGKRVDYSARSVIVVGPELKMHECGLPKNMAAELYKPFVI
                     RKLIERGIVKTVKSAKKIVDRKEPVVWDILEYVMKGHPVLLNRAPTLHRLGIQAFQPK
                     LIEGKAIQLHPLACTAFNADFDGDQMAVHLPLGNEAVLEAQMLMLASHNILNPANGAP
                     ITVPSQDMVLGLYYITKLRKGTQGEGLTFYGPEEATIAYNEKKLDIHAPIHVYVEDLD
                     ANGNLVKTMVETSVGRLMVNEFVPKEIGYVNEVLGKKSLRDIIGRVIKACGVARTAQF
                     LDDIKNLGYYMAFKGGLSFNLADVLIPPEKDELVQKGYDEVEQIMANYNMGFITNNER
                     YNQIIDTWTHVNSNLSNILIKQLTADNDGFNSIYMMMDSGARGSKEQIRQLSGMRGLM
                     AKPQKSGAEGGQIIENPILSNFKEGLSVLEYFISTHGARKGLADTALKTADAGYLTRR
                     LVDVSHDVIVNEEDCGTLRGLVCTELKNNEEVIASLYERILGRVSVHDVIHPITGEVI
                     VRSGEEIREDAAKAIQDSPIESVEIRSVLTCESKKGVCAKCYGRNLATNRMVQKGEVV
                     GVIAAQSIGEPGTQLTLRTFHVGGIASNIATENSITSKYDGILEIDELRAVEAVDEVS
                     GKKHLVVVSRLAEMRIVDPNTKIVLLTHNIPYGSKLFFNNGDSIKKGDVIIEWDPFNA
                     VIVSEVSGKIEFESLVENVTYKVESDETTGLKEKIIIESKDKTKAPAAHIVDENGNYL
                     KNYSLPLGAHVVKDNGDVVKAGEVLVKIPRAVGKAGDITGGLPRVTELFEARNPSNPA
                     VVSEIDGEVGFGKIKRGNREITVTSKLGEVKKYMVPLSKQLLVQENDYIRAGMPLSDG
                     ATTPSDILAIKGPTAVQEYIVNEVQDVYRLQGVKINDKHFEVIVRQMMRKVEVVDPGD
                     TRFLEQQIVDKLEVMDENDRIWGKKVVTDPGDSQTLQAGQIVTARKLRDENSMLKRRD
                     LKLVEVRDAIPATANQILQGITRAALQTNSFMSAASFQETTKVLNEAAINGKVDRLEG
                     LKENVICGHLIPAGTGQREFDKLIVGAKDEFDRIFANRKNVVDFNAMDKDDEE"
     gene            complement(50080..53892)
                     /gene="rpoB"
                     /locus_tag="ACZPB4_01750"
     CDS             complement(50080..53892)
                     /gene="rpoB"
                     /locus_tag="ACZPB4_01750"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007212060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed RNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HIR1096984.1"
                     /translation="MSSTAENQRVNFASIKNQFPYPDFLEVQLKSFQDFLQLDTPPEK
                     RKKEGLYKVFAENFPIADTRNNFVLEFLDYYIDPPRYCIDECIARGLTYSVPLKAKLK
                     LYCTDPDHEDFDTVIQDVYLGPIPYMTDRGTFVINGAERVVVSQLHRSPGVFFGQSTH
                     ANGTKLYSARIIPFKGSWIEFATDINNVMYAYIDRKKKLPVTTLLRAIGFESDRDILE
                     IFNLAEEVKVTKANLKKFIGRKLAARVLKTWVEDFVDEDTGEVVSIERNDVIIDRESV
                     LDSDNIEAILDSGTQNILLHREDQNLSDYAIIYNTLQKDPSNSEKEAVLYIYRQLRNA
                     EPADEASAREVITNLFFSEKRYDLGEVGRYRINKKLGLTTSADVKVLTKEDIIEIIKY
                     LIELINSKAIVDDIDHLSNRRVRTVGEQLYNQFGIGLARMSRTVRERMNVRDNEVFTP
                     IDLINAKTISSVVNSFFGTNALSQFMDQTNPLAEITHKRRLSALGPGGLSRERAGFEV
                     RDVHYTHYGRLCPIETPEGPNIGLISSLCVYAKINDLGFISTPYRKVADGKVDFSEEG
                     LQYYTAEEEEELTIAQGNAPLDDNGKFIRDKVKARFEADFPVVPPSEIDLMDVAPQQI
                     ASIAASLIPFLEHDDANRALMGSNMMRQAVPLLRTDAPIVGTGIEAQVARDSRTQIMA
                     EREGEVVFVDATCIKIKYDRTEDEEFVSFEDAVKTYNIPKWRKTNQSTTVDLKPTCHR
                     GQRVKAGDILTEGYSTQKGELALGRNVKVAYMPWKGYNYEDAIVLNERMVREDFFTSV
                     HVDEYILEVRETKRGMEELTSDIPNVSEEATKDLDERGIVRVGARIEPGDILIGKITP
                     KGESDPSPEEKLLRAIFGDKAGDVKDASLKATPSLRGVVIETALFSKAVKKRKSRLTD
                     KAILPKLDEEYEEKMASLKTLLVDKLLVLTNGKVSQGVKDYMNTEIIAKGAKFTRKSL
                     EELDYNSIQVSKWTADAQKNELIKQVILNYLKKYKELDAELRRKKFDLTIGDELPTGI
                     VQMAKVYIAKKRKIQVGDKMAGRHGNKGIVSKIVRQEDMPFLEDGTPVDICLNPLGVP
                     SRMNLGQIFEAVLGWAGRELDVKFATPIFDGATLDDLNEWTDKAGIPRYGKSYLYDGG
                     TGERFDQPATVGVTYFLKLGHMVDDKMHARSIGPYSLITQQPLGGKAQFGGQRFGEME
                     VWALEAFGAAHVLQEILTIKSDDVVGRSKAYEAIVKGDPMPQPGIPESLNVLLHELRG
                     LGLSFTLD"
     gene            complement(54000..54377)
                     /gene="rplL"
                     /locus_tag="ACZPB4_01755"
     CDS             complement(54000..54377)
                     /gene="rplL"
                     /locus_tag="ACZPB4_01755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002558082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HIR1096985.1"
                     /translation="MADLKAFAEQLVNLTVKEVSELATILKEEYGIEPAAAAVAVAGP
                     AAGGAAAAAEEKTSFDVVLKAAGANKLAIVKLVKELTGLGLKEAKDMVDSAPSAIKEG
                     IAKADAEALKKQLEEAGAEVELK"
     gene            complement(54428..54958)
                     /gene="rplJ"
                     /locus_tag="ACZPB4_01760"
     CDS             complement(54428..54958)
                     /gene="rplJ"
                     /locus_tag="ACZPB4_01760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HIR1096986.1"
                     /translation="MRKEDKGTVIGQLTETLKEYPNFYLTDIEALDAEKTSKLRRECF
                     KREVKLVVVKNNLLKKALENIEGDFSDLNVALKGNTAVMFSQVANAPARLIKDFTKDA
                     KKGVVAKPALKAAYVQESFYVGAENLEALVNIKSKNELIADVIALLESPAKNVISALQ
                     SSGQTIHGLLKTLEER"
     gene            complement(54973..55671)
                     /gene="rplA"
                     /locus_tag="ACZPB4_01765"
     CDS             complement(54973..55671)
                     /gene="rplA"
                     /locus_tag="ACZPB4_01765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HIR1096987.1"
                     /translation="MSKLTKNQKLALGKIEAGKAYTLKEASALVKEITTTKFDASVDV
                     DVRLGVDPRKANQMVRGVVSLPHGTGKQVRVLALCTPDKEAEATAAGADYVGLDEYIN
                     KIKGGWTDIDVIITMPSIMGKIGALGRVLGPRGLMPNPKSGTVTNEIGNAVKEVKQGK
                     IDFKVDKSGIVHTSVGKVSFTPEQIRDNAKEFISTLIKLKPTAAKGAYIKSIYLSSTM
                     SAGIKIDPKSVEEN"
     gene            complement(55687..56130)
                     /gene="rplK"
                     /locus_tag="ACZPB4_01770"
     CDS             complement(55687..56130)
                     /gene="rplK"
                     /locus_tag="ACZPB4_01770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007755660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HIR1096988.1"
                     /translation="MAKEVAGQIKLQIKGGAANPSPPVGPALGSKGINIMEFCKQFNA
                     KTQDKAGKILPVVITYYADKSFDFVVKTPPVAIQLLEATKKKSGSAQPNRAKIAEITW
                     EQVKAIAEDKLVDLNCFTVESAMRMVAGTARSMGITVKGTFPGNN"
     gene            complement(56198..56740)
                     /gene="nusG"
                     /locus_tag="ACZPB4_01775"
     CDS             complement(56198..56740)
                     /gene="nusG"
                     /locus_tag="ACZPB4_01775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005844824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HIR1096989.1"
                     /translation="MSDIQKKFYVLRAISGKENKVREYLEAELKNTDLGEYVSQVLIP
                     TEKTFTVRNGKKVMKERAYLPGYVLVEAALVGEVAHRLRNIPNVIGFLGGSDTPVPLR
                     PAEVNRILGTVDELQEQQEDLDIQFYVGESVKITFGPFSGFTGIIEEVNAEKKKLKVM
                     VKVFGRKTPLELGYMQVEKE"
     gene            complement(56752..56946)
                     /gene="secE"
                     /locus_tag="ACZPB4_01780"
     CDS             complement(56752..56946)
                     /gene="secE"
                     /locus_tag="ACZPB4_01780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HIR1096990.1"
                     /translation="MKKIITYIKESYNELVYKVSWPTRAELSNSAVVVMFASLIIAAL
                     IFVVDGAFEAVMRFFYNQIF"
     gene            complement(56965..57037)
                     /locus_tag="ACZPB4_01785"
     tRNA            complement(56965..57037)
                     /locus_tag="ACZPB4_01785"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(57002..57004),aa:Trp,seq:cca)
     gene            complement(57090..58277)
                     /gene="tuf"
                     /locus_tag="ACZPB4_01790"
     CDS             complement(57090..58277)
                     /gene="tuf"
                     /locus_tag="ACZPB4_01790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005637139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HIR1096991.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLAKKGLSEL
                     RSFDSIDNAPEEKERGITINTSHVEYQTANRHYAHVDCPGHADYVKNMVTGAAQMDGA
                     IIVVAATDGPMPQTREHILLARQVNVPRLVVFMNKCDMVDDEEMLELVEMEMRELLSF
                     YQFDGDNTPIIRGSALGALNGDAQWEDKVMELMEACDTWIPLPPREIDKPFLMPVEDV
                     FSITGRGTVATGRIETGIVKVGEEVQIIGLGAAGKKSVVTGVEMFRKLLDQGEAGDNV
                     GLLLRGIDKNEIKRGMVICHPGQVKEHSKFKAEVYILKKEEGGRHTPFHNKYRPQFYI
                     RTLDVTGEITLPEGTEMVMPGDNVTIEVELIYPVACSVGLRFAIREGGRTVGAGQITE
                     LEN"
     gene            complement(58327..58398)
                     /locus_tag="ACZPB4_01795"
     tRNA            complement(58327..58398)
                     /locus_tag="ACZPB4_01795"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(58364..58366),aa:Thr,seq:ggt)
     gene            complement(58409..58481)
                     /locus_tag="ACZPB4_01800"
     tRNA            complement(58409..58481)
                     /locus_tag="ACZPB4_01800"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(58446..58448),aa:Gly,seq:tcc)
     gene            complement(58526..58608)
                     /locus_tag="ACZPB4_01805"
     tRNA            complement(58526..58608)
                     /locus_tag="ACZPB4_01805"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(58572..58574),aa:Tyr,seq:gta)
     gene            complement(58628..58701)
                     /locus_tag="ACZPB4_01810"
     tRNA            complement(58628..58701)
                     /locus_tag="ACZPB4_01810"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(58665..58667),aa:Thr,seq:tgt)
     gene            complement(58795..59094)
                     /gene="hpf"
                     /locus_tag="ACZPB4_01815"
     CDS             complement(58795..59094)
                     /gene="hpf"
                     /locus_tag="ACZPB4_01815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005782154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0045182 - translation regulator activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome hibernation-promoting factor, HPF/YfiA
                     family"
                     /protein_id="HIR1096992.1"
                     /translation="MDVRIQAIHFDATAQLEAFIQKKVSKLEQYFDGIILAEVTLKVV
                     KPETVKNKQASIMLSVKNGECFADKINDTFEGAIDDCVEALEKQLVKFKEKIRAK"
     gene            complement(59084..59992)
                     /locus_tag="ACZPB4_01820"
     CDS             complement(59084..59992)
                     /locus_tag="ACZPB4_01820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HIR1096993.1"
                     /translation="MLIDDFLNYLRYERNYSNYTIGAYSKDLDQFQRYVREHREGVFD
                     PGEIDSDFVRSWIVSLMDEKLSPVSVNRKLSSLKSFFKFLMKRGIVSANPLRLVSGPK
                     TKKPLPYFIKDSELEALLDGDGFDEDFEGVRNRLVIEMLYDTGMRRSELIGIRNVDVD
                     YEAMQVKVTGKRNKQRLIPFAEGLKNLMLAYTEVRDREVEAAGEWFFVRKNGNQLSTG
                     IVYNIVKKQLSEIPMLAKRSPHVLRHSFATSMLNNGAELNAVKDLLGHSSLASTSVYT
                     HTTFEELKKVYHAHPRAKKEGGYYGR"
     gene            complement(60066..60257)
                     /gene="rpsU"
                     /locus_tag="ACZPB4_01825"
     CDS             complement(60066..60257)
                     /gene="rpsU"
                     /locus_tag="ACZPB4_01825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018667902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HIR1096994.1"
                     /translation="MIVVPLKEGENIEKALKKFKRKFEKTGVVKELRGRQAFEKPSVT
                     KRKQTMRAIYVQHLQQVEE"
     gene            complement(60342..61379)
                     /gene="mtnA"
                     /locus_tag="ACZPB4_01830"
     CDS             complement(60342..61379)
                     /gene="mtnA"
                     /locus_tag="ACZPB4_01830"
                     /EC_number="5.3.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046523 -
                     S-methyl-5-thioribose-1-phosphate isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S-methyl-5-thioribose-1-phosphate isomerase"
                     /protein_id="HIR1096995.1"
                     /translation="MIQTLSDLKTVRFNEQADGVIILDQTLLPGKEAYLTLTTAEEIW
                     DAIYKLKVRGAPAIGVAAAYGIYVCARRIDTAEKSVFVNEFRKIKEYLAGSRPTAVNL
                     VAALNRMERVLVAHPTLSVPEWKELLYKEAIAIREEDAAACRQIGENCLELLRPGMGI
                     LTHCNAGHLAVSEYGTALAPIYLGQERGYGFKVFADETRPLLQGARLTAYELSRAGVD
                     VTLICDNMASIVMRKGWVHAVVVGCDRVAANGDVANKIGTSGVAILARHYKIPFYVLG
                     PTSTIDGSCPDGDSIVIEERNPDEVTEMWYSRRMAPKDVKVYNPAFDITPHELITAII
                     TEKGIFCKNNR"
     gene            complement(61394..62251)
                     /locus_tag="ACZPB4_01835"
     CDS             complement(61394..62251)
                     /locus_tag="ACZPB4_01835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1096996.1"
                     /translation="MRNLLYLFVFAALLLGLSACSSYYYSMLNSNDPVGEKNERGDFV
                     QENDTVRISYRFWGENAPVTITIYNKLDEPLYVDWGRSALIIDDVATTYDPKVASVRG
                     ESSSVASGSSFHWSDRSSSGWSYSEGSFSGDVSLPKGVEFIPPHSKLVNTPLQLANFP
                     FNEIPKEEYVKEQMTTKANTTVNIRVKDFTEEDSPLRFRSYLTLFAGGTNGKPLKHSS
                     FERNFYLAKLIKVGDVAPQYFDEGQQQSGDFFYVKETHGATAGLVVGAIAVTAAGVAI
                     EATLGPVNY"
     gene            62653..63288
                     /locus_tag="ACZPB4_01840"
     CDS             62653..63288
                     /locus_tag="ACZPB4_01840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HIR1096997.1"
                     /translation="MSANYKLVRNPNPNPEESGKSLPLHPRLVSCGTIHTDEFINRAK
                     SRSSFSPADMKGILQLFQDMMVDFLMYGYNVELEGIGTFSVSLKSRPVMEKNEIRAES
                     IHFKDVKFRSSKELRDRLKTMPVFRDEYTVSDPAYPSAKECEQEVFRYLETNPFIHQK
                     KYMSLCGCSRSKASLDLRRLVEEGKLRWEKLGTSHLYYKVEEPVSGETNPK"
     gene            63333..65120
                     /locus_tag="ACZPB4_01845"
     CDS             63333..65120
                     /locus_tag="ACZPB4_01845"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HIR1096998.1"
                     /translation="MKTNIPERIAALREAMRQQKVDAYIIPSSDPHLSEYPADRWKSR
                     EWISGFTGSAGTIVVTADKAGLWTDSRYFLQAASQLEGSGIELYKLALPETPSITEFL
                     LHELHAGQAVGLDGQTYSAAEASALANKLSRKEIKLDTSADLIEGIWKDRPAVPGNPI
                     FEMPEALSGASVHEKLDLINNQLRSEGADCLILAALDEIAWTFNIRGTDVTYNPVVVS
                     YAFVSEDESVLFIKPEKLTAEITEHLKKEGVTLAEYSMIQRYLSRLPENSRVFVDMNK
                     TNVSLYDAIPGNCTIVEGISPANHLKSIKNETEIKGFQNAVVKDGVALTKFYIWLEKQ
                     MAEGAQVTEISAAEKLTALRAEQPQYIMDSFGTICGYAEHGAIVHYSATPETDATLKP
                     EGLLLIDSGAQYLDGTTDITRTIALGEPTEQMKKDFTRVLKGTISLAKSKFPAGTRGS
                     QIDILARKALWDSGINYLHGTGHGIGHCLNVHEGPQSIRMEENPVTLKPGMVISDEPA
                     MYRTGEYGIRTENMILVREDSETEFGKFLGFDTLTLCFIDTSLIIIPMLSVREHAWLN
                     KYHQMVYDKISPFLDEEEKAWLKEKTTEI"
     gene            65131..65646
                     /locus_tag="ACZPB4_01850"
     CDS             65131..65646
                     /locus_tag="ACZPB4_01850"
                     /EC_number="4.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004291294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HIR1096999.1"
                     /translation="MALIKSVRGFTPKIGKDTFLADNATIIGDVEIGEGCSIWFGTVL
                     RGDVNSIRIGNGVNVQDGSVLHTLYEKSTIEIGDDVSIGHNVTIHGAKICNGALIGMG
                     SVVLDHAVVGEGAIIAAGSVVLSKTIVEPGSIYAGVPAKFVKKVDPEQAKEINQKIAK
                     NYHMYSSWYKE"
     assembly_gap    65693..65792
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <65793..66836
                     /locus_tag="ACZPB4_01855"
     CDS             <65793..66836
                     /locus_tag="ACZPB4_01855"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HIR1097000.1"
                     /translation="LPKIDQYPIFENRVVKAGSPRPWELSEAYNTKSIPERYLPRFEE
                     LGTVAYVIIQDNRLLFEQYWEDYSPESHSNSFSMAKSIVSLAIGCAIDDGFIRDVDQP
                     VSDFFPEFKGYDGKALTLRHLLTMSAGVDFDEAYNSPFSPTTQLYYGDDLQEIAFGMK
                     EIDEPGVNFIYQSGVTQLLGFIVEKATGEKLSDYVSRKLWTPMHAEESALWSLDRKDG
                     MEKAYCCFNSNARDFARFGQLLLNNGQWDDRQLISPAYLAEATSPDTRLVYKDLGKPN
                     HCYGFQYWILDYKGMKIPYMRGILGQYVFTLPKKNAVIVRLGHKRSDTYTADQHYPDD
                     INTWLDAAMDLLQ"
     gene            66873..67991
                     /locus_tag="ACZPB4_01860"
     CDS             66873..67991
                     /locus_tag="ACZPB4_01860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate-binding family 9-like protein"
                     /protein_id="HIR1097001.1"
                     /translation="MRKTILTTAPLAALLLLSCAQKPSTQKPDITYMPQPPFNPPTYV
                     CYKAPAPIKIDGKLSPGEWDAIPWTSDFVDIEGDKRPAPHFQTRAKMTYDDNGMYFAV
                     LMEEPHVWATITEHDAVIFHDNDFEIFLNPTNDTHNYLEYEVNALGTEWDLFLTRPYR
                     DNPQVLNNWEFAGMKSAVYVDGTLNNPKDTDKSWSVEVFIPWTSVFQMDRGKEKPEIG
                     EQIRVNFSRVEWTTDVKDGKYVKVPIQGEDKIREYNWVWAPTGVINIHMPEYWGYVQI
                     SDKIAGEGETPFVKHPSEETKWILRNLYYRQNEFAATFGHYADNINDLKANELCPQEI
                     ANQLEIHTTPSMYEISLPAPDGTVWNIRQDGLVWPKKK"
     gene            68019..69422
                     /locus_tag="ACZPB4_01865"
     CDS             68019..69422
                     /locus_tag="ACZPB4_01865"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HIR1097002.1"
                     /translation="MKQKNLWIAALALGITLSAHGQQSGGGISPTMLQQIKQSYQGTP
                     ADKAIRNAITNNDINKLAVNGESKNNLDTYFSNKVESKGISNQRSSGRCWLFTGLNVF
                     RAQAIHKYDMGEFQFSQNYSFFWDQLEKANLFLQGIIDTRLKPMDDKMVEWLFKNPIG
                     DGGQFTGVSDILTKYGVVPAEVMVETNSSNSTGRMSNLIGLKLKEYGLQLRDLSTTKG
                     TTVADLEKKKTEMLGTIYRMLVLNLGEPPTKFTWTRKDAKGNPVETKEYTPQSFFQEY
                     IGDDLRNNYVMLMNDPSRDYYKLYEIDYDRHAYDGKNWTYVNLPIEDIKQMAIASIKD
                     STMMYFSCDVGKFFDRDRGILDVNFYDYGSLMGTTFGMDKKQRIQTFASGSSHAMTLM
                     AVDLDANGKPKKWMVENSWGPGANAGHLIMTDQWFNEYMFRLVVNKKYITDQVKEILK
                     QTPTRLPAWDPMFAEED"
     gene            complement(69557..70792)
                     /locus_tag="ACZPB4_01870"
     CDS             complement(69557..70792)
                     /locus_tag="ACZPB4_01870"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-D-manno-octulosonic acid transferase"
                     /protein_id="HIR1097003.1"
                     /translation="MYSLAIHLYAFVVALISPFHKKARLMRFGQWKTNSILREKIDRN
                     AKYIWFHASSLGEFEQGRPMIEKIKAEHPEYKVLLTFFSPSGYEVRKNYKGADVICYL
                     PFDTPFRVKKFLNLANPAIAIFIKYEFWGNYLRELRKRGIPVYIISAIFRPDQLFFQW
                     FGKPYRKMLSYFNHLFVQDERSMKLLNEFGITNVTVTGDTRFDRVLDVRKQARELPFI
                     ERFLESKEGKRPIVMVAGSSWPQDEAIFIPYFHEHPEMKLIIAPHEIHREHLLSIEAM
                     LKRPSVRLSEAHEDDLADKDCLIIDSFGLLSSIYRYGQIAYIGGGFGAGIHNTLEAAV
                     YGMPVLFGPRYHKFKEAKDLIAVGGGFSITDDSSFRTKMDELLTDPTALETSGQAAGD
                     FVKNSVGATDQILRQIHIR"
     gene            complement(70795..72312)
                     /gene="gltX"
                     /locus_tag="ACZPB4_01875"
     CDS             complement(70795..72312)
                     /gene="gltX"
                     /locus_tag="ACZPB4_01875"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010184083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HIR1097004.1"
                     /translation="MTQRKVRVRFAPSPTGALHIGGVRTALYNYLFAKQNGGDMILRI
                     EDTDSQRFVPGAEDYIIEALTWLGIKFDEGVSFGGNYGPYRQSERREIYKKYVDQLLN
                     DGHAYIAFDTPAELEEKRKEIANFQYDASTRSQMRNSLTLSQEEVQSLIESGHQYVVR
                     AKIEPNEDIHVNDLIRGEVVINSSILDDKVLYKSADQLPTYHLANIVDDHLMEVTHVI
                     RGEEWLPSAPLHVLLYRFFGWEDTMPSFAHLSLLLKPEGNGKLSKRDGDRLGFPVFPL
                     EWHDPKTGDVSSGYRESGYFPEAVVNFLALLGWNPGNDQEVMSMDDLIRLFDLSRCSK
                     SGAKFDYEKGRWFNHHYLLEKSNAEIADLFLPIVESHGIQTTHAYVEKVVGMMKGRVN
                     FVSELWDLCSFFFIAPTEYDEKTRKKRWKEDSAVQLGEFIEQLRAREPFDVEGTENEC
                     KAWIESKGYHLGNIMNAARLALVGEGKGPGIFDITEALGKEESIRRIQRAIEILK"
     gene            72408..74447
                     /locus_tag="ACZPB4_01880"
     CDS             72408..74447
                     /locus_tag="ACZPB4_01880"
                     /EC_number="3.1.4.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0106409 - cyclic-di-AMP phosphodiesterase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HD family phosphohydrolase"
                     /protein_id="HIR1097005.1"
                     /translation="MKQKNYNIPTVVYFVVTALLIAYFFPREGKFRYQFYEGKPWRYG
                     LLTAPSDFPIYKTDDEVKAEKDSVLRKFEPYYRMNPDIQKQEVEKLRANYNNGNNLRS
                     KVSPAYMQYIESSLINLYKNGIISSQDLDELRKEEYSRVNLLENAVAQTRYVSDFFTV
                     RTAYEFIINNCPPRLDKSILQSCDINNYLTENISYAADMSDKIKEDMLQSVSIANGMV
                     QAGERIVDRGEIIDNHTYNVLRSLKAIHEAKTGGTQTQGIILAGQFVLVFGLMFCFWL
                     YLWSFRLKIFHNRKNVLFLILCIFVSCIFTELCVTYALFNVYILPFAIVPIVVRTFFD
                     SRTALFTHLIIVLICSLMVPFPHEFLLLQIVAGMVVTFSLKELSERSQLIRCAVFIFL
                     SYAACYLSLTLYQEANLNKINWMMMLYFGINFILLMFTYVLVYMLEKTFGYVSSITLV
                     ELSNINNPILKKLSETCPGTFQHSLQVSILASEAAAKIGANAQLVRTGALYHDIGKMS
                     NPVFFTENQSSVNPHNQLSFDQSAQIIISHVTEGVKIAEKALLPKAVISFIRTHHGRG
                     KAKYFYNSFKNQYPDKPINDELFTYPGPNPFSKETAVLMMADSVEAASRSLKEHTEES
                     ISALVNKIIDGQIADGLLKSAPLTFKDVETIKSVFVDKLKTMFHTRISYPDLKKQ"
     gene            74457..75635
                     /locus_tag="ACZPB4_01885"
     CDS             74457..75635
                     /locus_tag="ACZPB4_01885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HIR1097006.1"
                     /translation="MNDHLLYLASTGIVAFTCLLVSGLLLSLKTLRESTIPKYRTACK
                     YLALASALVGIGHIFILSSGTDERTIMELFYFPILLISASQALLFTFLLTLLFRGKNV
                     TRRNILLHAMPTIALTVAYTIACLFREDVHTYRFDVWWDNIGNPPLLIRTLTCLVYLV
                     QLGGYTHFFFRERAIYLGNLKQIPQSPERLELRWVTRAFLWALGIGIAAVSLCFFPNN
                     YYNTAVNFVFALFYASVSIHYANYHYTYDQLYLRLNLAPQADADTDPNRMDLEDLIGG
                     LLEIEEDELFQQAQNYMASSSPFLNPNFSRQDLVRALGTNEKYLSTSIKDKLNITLKE
                     YIDRYRVNHARTELLMPGDSRSMEEIAVGAGFTSSRTFSRIFQKILGVTPAQYRRQAQ
                     "
     gene            75741..76502
                     /locus_tag="ACZPB4_01890"
     CDS             75741..76502
                     /locus_tag="ACZPB4_01890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4469 domain-containing protein"
                     /protein_id="HIR1097007.1"
                     /translation="MAEQIILNTDLYDNLLTERKGDYTAKPRITGTLYNTDIAARIVA
                     ARTEYQHGTILNILDMADSHKVQAIAEGKSVVDGVGQYLVNVQGAFEGEKAQFEPGKH
                     ALGITYTMGKLLRETLKLVKVVVNGVAAVGPVINTVTDSTSKAINGQLSSGGALVLGG
                     VNLKIQGDDPSIGVYLTPTTEGAAPMKAPVVIANSPSQVIVQMPTLADGQYTVSLTTQ
                     YSGSRNVKEPRTYTFPIILIVGEGGGGDSESPDEI"
     gene            76615..>76862
                     /locus_tag="ACZPB4_01895"
     CDS             76615..>76862
                     /locus_tag="ACZPB4_01895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097008.1"
                     /translation="MRTSLHDIHLPARRIFALLISVATLIATLPTAARAQAEPPGALD
                     LATLPGTLNNNWYINLAYLNGTWVYKVGASDTQAPTTGT"
     assembly_gap    76863..76962
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <76963..>79033
                     /locus_tag="ACZPB4_01900"
     CDS             <76963..>79033
                     /locus_tag="ACZPB4_01900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097009.1"
                     /translation="SADPDSGNPPALTLKDAVITSSFNQLFYIKAGAEPTLRIEGENR
                     IEIMSDLIYNLGTLTLTVADAQEISQGILNGSPAGTGTLTVYAQAPLSIGAISNFQNA
                     RMHLDGEIHVISKTGGSAFKNDNTSPDAITFGDNARIHLQANALCTYVSGFIELDFDT
                     APTDGRTLSVTPAGDDEPAATFATDGTCWGYAFLAAADTRYTASLDGERLYAGRRYSG
                     SSYKDGDYPFFRTDGAYCRYSGATATRPTPQPLDLSKDYGYGSTRTGIDLFFDPADGW
                     YCDEKMFDGTVTTNGSSSYINIPATIHAEGEATLTLDKVNFQLPTGTALTVASGTVTL
                     QNNTYNALLSGTHALRVETGATCLISPPADPDNTLALTAAEQAIHPEGGGTVKGLVQL
                     TWPESPSGYIYLKPAEPAENPNGLTFNITGMKSIATNYPLSFYLENQSTGLKQEGYRS
                     DDPEQTYLSTFPAAHPDRLTSYTGLREITPAWIVIDKETAFDASMPGQWLRVTEKGVL
                     TVGKIGENGVFPLVNDLELQDGGQIRFADDGVLGLVAARFTHLFPNRNQWRATTLAAD
                     NADKLAGDAGTPCYVRTGYPDATDQTWQPADPDNLYMQFAAGDPVLIAGEGPETDTLR
                     LNYGNTYLFKDSPDSPVEPTSPAEPLNMGVFLFKGNRASYNVEMRNIYVLSDDGSRFE
                     LKDRVTLR"
BASE COUNT        21992 a        19930 c        17011 g        19900 t
ORIGIN      
        1 gttacagaat cccagaatca agaaaatcac cgaggtactg gctcctacgg cagccagcga
       61 attaatacct agaaatttac caacgatagc ggcatcgatc aaagaataag tctgctgaag
      121 cagattccct aataacaatg gcatcgtgaa actgaataga agagggaata cagcacccct
      181 cgtcatctct tttgagtttg ccatacatct aaattaaaag gataaacaaa gaggatagaa
      241 aaactgatta gtcatcgcaa aggtaacaac cctaaggtaa aacgcaactc tctccatcat
      301 tatttcaaac cggaattcac ataaaataac aatgcccatc gtaaggtctt tacaatgggc
      361 atcgtaaggt gcttagaatg cctattgtaa caggcttaca atgggcatca tggttttctt
      421 attccaacga gaaagaatag gggcgatcac tatcctgcgt acctcgctgt ttattagggg
      481 tatcgctcat ttggtattga attttcgcac cacctagcaa ctgctcgtgt gtcaagaaat
      541 tgcgggtata tgtcttgccg tttactttca tacccttgat gtaacggttc tcccgatcag
      601 ccttgtccgc ttggatcaac acctgctttc cgttatccag atggagtttt acggatttga
      661 acaaaggggt acctaataca tattggtcgg tacccggaca tacggtatag aagcctaagg
      721 cagagaatac ataccatgcg gaagtctgtc cgttatcctc atcgccgcaa taaccatccg
      781 cctcagcggt atagagctta tgcatgatct cgcgcaccca gtattgggct ttccaaggct
      841 cgccggaata gttgtataga tacaccatat gctggatggg ttggttgcca tgggcgtatt
      901 gtcccatgtt cattacttgc atctcacgca tctcatggat cataccgcgg ctatccatac
      961 ccaaacgact aggcatcttg aagacggaat ccatcatatg attgaattcc ttctttcctc
     1021 ccattaagtc gatcaggcct tgcgggtcgt ggaaaacaca gaaactccaa tgccagctgt
     1081 ttccctcgca gaaatcacgg ctccagtccg tacctttaaa agtcggattg aactcgccct
     1141 tatcagagcg tccgaccatc aacttatatt ttgggtcgta cacattctta tagttgttag
     1201 cccgttgctt gaagatatcg atctcgcttg ccggcttgcc aagttttttg cccaaggtat
     1261 aaatcgtcca gtcattataa gcatattcca aggtacgagc cacgttttgt ccgataccga
     1321 tattattcgg tacataaccc agtttattat actcctcgta agcgacacga ccggaagccg
     1381 ttctcggcag ttggctattc gcgtcatgct tcaaggcttc ccaaagcgtc tcgatatcgt
     1441 atcctctcaa gcctttgata taagcgtcgg ctaccacgga agcggagtta ttgccgacca
     1501 tgcaatcccg gtggcccgga cttgcccatt ccggcaagaa accgctctct ttataagcgt
     1561 tcaccaaacc ttcctgcatc ttttggttca tctccggata catcaggttc aagaagggga
     1621 aaagacagcg gaacgtatcc cagaaaccgg tatcggtaaa catatagccc ggcaagacct
     1681 caccgttata agggctataa tgtacgactt ggcccttggc atcgatctca tagaagctac
     1741 gagggaaaag caaggaacga tacaagcaag aatagaaagt acgcaagtta tcgatgttcg
     1801 tatcctctac ctcgatctta cctaattccc ggttccagat ttccttccct ttggtcacta
     1861 gctgatcgaa accagtatct cccacctcac gcaagtttaa ctcggcctgc tcggtgctga
     1921 tgaaagaaga agccacgttg gcatgcacca cctcgccggc ctttgtctca aaaccgatga
     1981 tagcgccggc atggtttgtc ttcacctccg actcatccaa ctggatcgcc ccgttcttaa
     2041 ccgtagagga gaacgtgaat ggcttatcga attggatcac gaaataattc ttgaagttac
     2101 ggggaacacc gcccgtgttc ttcgtggaat aaccgatgat cttacgttcc gcaggcaata
     2161 cctttatata agagccttta tcgaaagcgt cgatgacgat atacgctttc ttggtttccg
     2221 ggaatgtaaa gcggaactta gccgcacgtt ccgtcggaac caactcggta gtcacgtcat
     2281 gatcggccag atagacctta taataataag gtgtagccac ttcgcctttg tgagagaacc
     2341 agctagcccg tttctcctcg tcgaagacca agccttcggt agtaggcata atggagaact
     2401 gcccgtaatc gttcatccac gggctcggtt gatgggtttg cttgaatccc cggatcttat
     2461 ccgcatcgta acgataggtc cagccgttgc ccatctcgcc ggtctgggga gtccagaagt
     2521 tcatacccca aggcatggcc gtggccggat aggtatttcc ggtagataat tcgtacttgg
     2581 attgggtacc gactaacgta ttcacgtagt ctacaggatt ctctacggcg gaaagctgca
     2641 tgcagcaagc tatccccatc gctaagattc ctttcttgaa aaaagatgtt ttcatgtttg
     2701 tatagaatat taatattgtc tgtattgatg agacggggcg tgccccgtct catcaacttg
     2761 gtgattgtgt aggcggtaac gttggccgct ttccggacag gtggcgaatc cttcggagtc
     2821 aaatacaagg cgatggccgt actcgcttac ccaaccgatc tggcgggatg gatttcctac
     2881 gaccagcgca taagccggaa catccttcgt taccaccgcc ccggcaccga tcatggcata
     2941 ccgcccgact gtatgtccac aaataatcgt agcgttagct ccgatcgagg cccccttgcc
     3001 aatcaccgtc tccttatact ggtctttccg agagatagcg ctacgcggat tggttacatt
     3061 tgtaaacacg caactaggcc ccaagaacac atcatcctcg caaatcaccc ccgtataaat
     3121 agacacattg ttctgtacct tcacgttatt ccctaagacc acgcccggcg atacgactac
     3181 attctggccg atattacacg tcctgccaat cacgcatccc gtcatgatat gggaaaaatg
     3241 ccagatatgg gttccttccc cgatctcaca accggcatcg attaccgctg tctcgtgcac
     3301 ttgataactc atatcaatcc ttttatttat agattaggaa aatagtgggc ttcttgctca
     3361 gatcgggaac tttacccgcc cattccttga ccgggcgagt atggatatac tcatcctcac
     3421 acgttatatt cgaggcaata cacagtttcg tagacggacg gcacgtacgg atcaactcct
     3481 cggccagttt attattccgg taaggagtct cgataaacaa ttgcgtctga tgctcggaat
     3541 aaattcttcc ctccaatttc ttgatcgtgt tcgttcgctc ggaagcatca atcggcagat
     3601 aaccgtgaaa agcgaaactc tgtccgttaa agcccgatcc catcaccgac atcaagatag
     3661 acgaaggccc gaccaacggt accaccggat aatccttccg ttgggcgata gccactacgt
     3721 cagcacccgg atcagcgatc gccggacaac ccgcctccga gatcacgcca acgctctcgc
     3781 ctttcgccaa aggagccaga taaccagcta cttgttccgg tgaggtatgt ttattcagct
     3841 cataaaatgt caagtcatcg atcacgatcc ccggctccac ctttttcaag aaacggcgtg
     3901 ccgtacgcac gttttccacg ataaaatgcc ggatggataa gatcacgtca cggttgtact
     3961 ctggtaaaac acggcgatgt tccgtatcgc ccaaggtaac tggtataagg aaaagagatg
     4021 ctcgcatact gtttgttttc cgcgaaagta gtatttttgc cgcaaactaa cagaataatc
     4081 atggcacttc ctattgattt tattacccgt acacgggctt tacttggcga ggagttcgat
     4141 cgtttagagg cagcgttaag cgctgatgtt cccgtaagta tccgtatcaa cccgatgaaa
     4201 gggactcccg ctcccaaagc aggtgctcca gtcgcttggt gcgagagcgg tttttatttg
     4261 ccggaacggt tgtctttcac cttcgatcct ctattccatg cgggggccta ttacgtgcag
     4321 gaagcgtctt ccatgtttct ggaacaagcg atcaaggcat acgtgaaaga gccggtacgt
     4381 tgcctggatt tatgcgccgc cccgggtggc aagtccacgc atctggcgag cttattgccg
     4441 gatggaagcc tgttagtgag caatgaggtg atccgcagcc ggagttatgt attggccgag
     4501 aatatcgcta aatggggcca cccggacacg atcgttatca ataatgaccc ggaggagatc
     4561 ggcgaggcat tgcctcatct gttcgacgtg atcgtcaccg acgtaccttg ttccggtgag
     4621 ggcatgttcc ggaaagatac ggatagcaca ggcgaatgga gcgtagataa cgtacggctt
     4681 tgcgcctccc gtgggcggcg catcatccat gatatctgga acgccttgaa acccggaggt
     4741 atcttgatct acagtacatg tacctataat acggaagagg atgaggagaa catacattat
     4801 ataatagagg agctgggagc cgaggcattg cctatcccta cccaagagga atggcagatc
     4861 accggcgccc tccggtttga acatccggtt taccgcttct tcccgcataa gacacggggc
     4921 gaaggctttt tcctcgccgc cctccggaaa gcggaaggcg agatcgagga aattcgtgtc
     4981 aagtccaaag ggaaaaaaga gcgaggaaaa gccgctctgt ccatcccaca ggaggcccgt
     5041 ctgttccttt cggatgaaac ttcgttttct ctcgaatgga acggcagttt ccttcgagcg
     5101 tatcccaaag cccattcgga tctattttca ctcatcaatg ccaagccttt acgggtactt
     5161 tccgccggta tttgcctagg agaagcgaaa gggaaagact ttatcccatc tcaagagctg
     5221 gctttaagta ctgccttaac ccccaatgca tttccatccg tggaactgga atgggaagac
     5281 gctattaaat tcttaaagaa agaggcgctc gtcttaccct ccggtacaga taagggatat
     5341 gtgttggtac gctaccaagg acttccgcta ggttttgtaa agaaccttgg caaccgggcc
     5401 aataacctgt atccgcaaga gtggcgtata cggacgggat atattccgga ggaaatcaaa
     5461 ctatttttag gacgataaga ccactataca ggcataaagc cacacgtata tacgtataag
     5521 accacactta cgtacgtgta ggccgatgcg tatatacgca tgaggttacg cctatatacg
     5581 tgagagaatc aatcctaatc cacgaatcgc aacgtaaaca aggcggcctc catccggcgg
     5641 atcaagttcg ccttttttga ttccggggca tagacaaagc tttccgctac gataacccgc
     5701 ccttttttct tgtcgagcag ggcatggctg acgaacgggc cgcccatctt atctccttcc
     5761 atacgccaaa gaccacgcaa tacgccgcgg tattcgccac gataggtgat cggctcgtaa
     5821 gaaagctcga aacgctgctc agtcttcata taagaattcg ggaaagagcc cggtacgttc
     5881 cgcttcacta cagaatcacg catagcgacc agataatctt cggtaaatgc ctcttgagtc
     5941 gtatagggaa aactatatac caagatatca gtccgtcccc gatttgcgtt attcgaaccc
     6001 caaaagaaat cggtctcttc cttataggcc gacatatctt ccggcacgaa cagcgagata
     6061 ccgaaacggg acttcaactt ctcattgatc caactgctat ggctcttaga aagtccaact
     6121 atccaacgtt ccctttccac tcgattgaaa tggttgacca accgtccttc atttaataaa
     6181 aggaactcgg ttaaagcagc ggtagtcgga gcatacagag tcacaacatt ctgaccgctg
     6241 gcccattcat cgggactctc tcttgttcca gctttcgtat accggttagg atctacagat
     6301 acgatcaaga tatttcgtac gtatcgtaat aaaccggaaa agcccgatgg ctccgaatag
     6361 gtgacacgca tagatgcttc cgcttgaggc aaagcaggta tcggcgctcg caattgttct
     6421 tgcagcaact cccccacctc accattccat gcgtctcgat ccattacaac caccacctcg
     6481 aaaggccatc cggtagcccg ccgtagcgag gccaccggag aggacgaagt ccaatcacaa
     6541 gcggaaagcc ccaccattag gctaaggctg atccatagta gtacagtttg tgttctcata
     6601 gcattcctga ttattcgttc ttaaaaatta aatcacacac cgcaaaagta caggaaggat
     6661 cgtaaagagg aaagaaatgg taccggacaa aacaagcgaa catcaaacaa ctaataatca
     6721 cacatataaa ccacgcaatg ggagataaac ggataatatt gccggacaat cacgacaaac
     6781 aaaataactt taagctttat aataaacgga cataggcatc caaatccgtc ttttcatcca
     6841 agcctagacg tttttttaaa cggcctttcg atttggttaa cgcatccgga gtattattaa
     6901 acacggctag ttgctccttt cgggagaaat tccatttgat caagcaacat atttcctgct
     6961 catggcgggt aatactgtat ttatttctca gatcggttaa gaagttatta aacagaagat
     7021 cggtcatacc aataatctca gcccattcct ctttacttgg attcacatgg agaggatcat
     7081 ctttaagggc acataaaagc ttaggtacat ccacatctac ttttccggta gcattgtcca
     7141 ataagttatt atcgccggaa agaacaagga tctctctctc caactgctcc atcttctggc
     7201 gataggccgt cagctccgtc tcgatccggt cataagcctc cgagcggatg accagagaat
     7261 cccgttcccg ctccaagcgt acgacttgct cttgatagga ggctaattgt tgtttatagc
     7321 gatacatatt cgctttattc tgccgaatgc gagaacggac agattcattt ctctcccgga
     7381 tacgtcccgt acgtactccc aacaaaaagc taaataccac cgccacgatc aaggctaagc
     7441 aaccagcccc ccaatcaaca aatccccaaa actcccccat cccggttacc gtatggattt
     7501 atttctcaaa taatcataga tagccaattg cgaacgcact tttaccggat tatcatcaca
     7561 cttaaaatta ttacgtaact cgccatccaa ataacaagct ttcacgttgt cacttagctg
     7621 gatattcaag atatcgatta tctccctctt cagatccgga tcgaggatcg ggaaagccgt
     7681 ctcgatccgt cggttcaaat tccgacgcat ccaatcagcc gaggtaagga aaagatcctc
     7741 ctgaccatca ttcagaaaat accaaacccg tgaatgctcc aaaaacatat ccacgatacg
     7801 agtaacccgg atgttagcgc tataaggttg gttcggtacc aggcaacaaa tcccccgaac
     7861 aatcagatcg atctctaccc ccgcctcact cgcatgatag agttcctcga tcatatgttg
     7921 gtcatgcagt ccgttcatct ttaatatgat ccgtcctttt cggccttccc gcacatgctc
     7981 gatctcccgc cgaatcctac cagtcaattc cgagaccata ttgaaacggg ccaccaacaa
     8041 atggcggaaa gtaggttctt tcatacgccc ttccaaaaca gcgaatactt tattgatatc
     8101 cgtaataatc tccgtattcg aagtcaacag cgccatatcc gaatagatct tagccgtctt
     8161 ctcattgaaa ttaccggtac tcaaataggc gaaatcacgc cgtttaagtc cctcggacgt
     8221 atccttccga agaatgaccg cgaccttcgc atgtactttc aagcccggaa tactataaat
     8281 gatacaaata ccggcctgct ccatacgctc tgccgtactc atattattct cctcgtcgaa
     8341 acgggctttc aattccacaa ataccgtcac tttcttacca ttctgggcag cgctgaccag
     8401 cgtattaatc acggccgaat tctctgccac tcgatactgg gtaatcttga tctcatccac
     8461 cttcggatca aaggccgcct ccatcaaaaa gcggatcaaa taatcgaatg actcataagg
     8521 gaaatgcaat aagatatccc gcttcttcac ggccttgaat accgacccca tctcatcgag
     8581 gaaaggcaca cgcataggca ccggtggctg ctgctccaaa tgctttcctg ccggattcgg
     8641 caatttcatc aagtcctgca aattattata tcgtccacct aacaccaagt cctccgacgt
     8701 aataccaaag gcatcgcaaa caaaagccag aaaatcatcc ggcatcgctt gatcatacat
     8761 aaaacggctc aaggctccga tcttgcgctt cttcaccttc ttacggatat tctccacgat
     8821 attcgcccgg ctctcatcat ccaaataaat atccgcatcc cgggaaatct tgatgctgta
     8881 acagccatca ataatataac cgggaaaaac attctgtaaa ttcgcacgga taatgtcgtc
     8941 gataaacatg atataatatt tcccgtcatg cggaggcaac tcgataaaac ggggaacttt
     9001 cgcataagga atcttcatca acgcataatg atactcgggt acgaagcccg gctcattcat
     9061 ccgcttgctc cgcttaatca tacggatcac aaggtaaagc cgacgatccc ggatgaacgt
     9121 acgtatatca ccggcttgaa tcatgaccgg cgacaggaat gggaaaacct cctcattaaa
     9181 gaaattatgg acaaactctt catggaaagg ttccggcttc tcattctggt ataagtaaac
     9241 attctggcga ttcaattccg gcaatatctt ttccgagaaa atacggtaat agtcccgttg
     9301 ctggcggtta acctcccggg tgatagccgc caaggtctct tccgcctcag ctgcgctctc
     9361 ctccgaataa ttctttttca tgattacccc ccgatgttcc gcaacccgga tctcataaaa
     9421 ttcttccaga ttcgaggaat agatagaaag gaacttaata cgctcataaa taggcagcgt
     9481 atcatcttcc gcttccagca agacacggta gttaaacgac aaccagctta agtcccgttt
     9541 aaaatattga tatgaattct ccataatatt cttatcttag gcgtgtaaat atagatactt
     9601 tcgagcaata aaagaaattg ttatgattaa agttggattg ctttcagaca cccatgcgta
     9661 ctgggatgat aagtacgccg aatattttaa agattgcgat gaaatctggc atgcgggcga
     9721 tataggctcc gatcttttgg ccgcgaaatt cgaggctttg aaacctttca aagccgtata
     9781 cggaaatata gacggacaag ccattcgcct gcaatatcct aaagtagctc atttcaaggt
     9841 agaagacgtg aacgttatga tgactcatat cggaggttat ccgggccgct acaatcccga
     9901 gatccgcaaa gaattatacg atacacggcc aaatctattc atctccggac attcgcatat
     9961 cctgaaagta gtattcgatc gaagcttgaa gtgtctgcat atgaatcctg gagcggctgg
    10021 aaaaagtggc tttcatcaag tacgtacctt attacgtttc gttattgagg gaaaggatat
    10081 caaagatttg gaagttatag agctagggaa tcgggcatta taagatgatt agttaccgca
    10141 acagaaactc tcggcgaaaa gaatcgtatt ttgcaaataa gcgaactctt tctcaaaata
    10201 ttcgctaaat accccggaac tcaagttctc ctcgatttgt ttcgctgtcc aaagctttcc
    10261 gctacggcgc ttacattgat ttaattgctc ttccgtacgt aaacaaataa catagagaga
    10321 taccaaatgt ttcaccttct cgttctcaaa tgtataacgg atcaggaagc gtggagcaat
    10381 tgatttatct tgcgccaaac ttccgagagt ctctttgacc gtgctatcta tactatgtcg
    10441 gaagagcacg taattatgga acggataatc catcgtatcc ggagagacaa actcatcctt
    10501 acttcgtctc accagatata acataccatt ataaacaacg gcgatacgca cgatcggatg
    10561 atagtatttc ttcggtaaag agcggctgac cgaacgtgcg atacaaccga tcaccttccc
    10621 attgtcattc aatacgggaa cccacatttc ctttttcaag ctaccttgca tcaaggacaa
    10681 acgtatttgc tcataaacaa tgaccaaaac accgattacc aatcccaact cccggtataa
    10741 gaaacgttcg gtacgcatat tctgcatcgt ttccggcaag atgctatata acaagatgat
    10801 gaaaagatgc aacgtgtaca ggttctgtac caactgagcg aggaaataaa attcgttcaa
    10861 ggtagtacga agcaaagtac gtttaaaaga gggacgtttc gaatcgcgta tacgttgtat
    10921 gaccgttctc ctcgtgaacc ccacgatcgc taacgccacg accagtaata cttccgtgat
    10981 aagaggagag tatataaaca acacaggttc aagcttgaga caaagaaata cggaatataa
    11041 gaccaatgtg cccgccgatg gcagaagcat aaattggtac accttatcct tactcaacac
    11101 ttgaaacaaa aaaatacaaa caaaacagaa agtaacccca attataaagg ataataaata
    11161 agaaaaataa ttgtccaaaa acatgaacaa caacaacggc aataaaccta tcgcctgatt
    11221 atctagacct ttctttactc tgttcattcc ttccccccct ttagtccact tttatattaa
    11281 taacaacaaa gattgtcaaa agttcatgaa tcatatatgc ttttccgcat ggtacgacga
    11341 gcgcaccagc ggagcgctct ctactttctt aaaacctttg ttaacggcct gttgtctata
    11401 atattcaaag cgttcaggag tcacatattc agagacggga atattcttgc gagagggctg
    11461 taaatactgc ccgattgtca aaacagaaac acccgcctgc aaaacatcat ccattaattc
    11521 aagcacctca tcctcagtct cccccagtcc gaccatgata ccagtcttgg ctaccacacc
    11581 ccgctcagcg attcgtcgca aaacggataa gctcacgtca tacttagcgg cgctacgcac
    11641 ttgcggactg atacggcgta cagtctccat attatgggag ataatctcag gcgccgcatc
    11701 cacgacctga tcaaccagat ccaatcgtcc ttgaaaatcc gggattaaga cttccacggt
    11761 cgtttgagga ttcacctctt tgatcgtacg gatcgtattt acccaatgag aagcgcctaa
    11821 gtctggtaag tcatcacgat caacggacgt gatcaccgca tgcttgagat tcattaaacg
    11881 gatgctctcc gctacattcg caggctcttt cgggtccaac ggaagaggtt tacccgttag
    11941 cgtattacaa aaacgacaag agcgagtaca gatctcacca ccgatcatga atgtagctgt
    12001 tccccggctc caacattcac ccatattcgg gcatttacca cttgtgcata ttgtgtgaag
    12061 gcaatgagat tcaacaatac tttttgtctt cgtgaattgc tcatttccgc caagccggat
    12121 cttcaaccaa tccggctttc ttaaatgctg cgccatgtct tacaaattat tgaataaata
    12181 attagccatc ttcgtataca aatggtaacg ggtattacca ccatatatgc tatgattccg
    12241 atctttataa acatgcatat cgaactgctt attggcttga accaaagcct cggcatattc
    12301 cattgtttgc ataaaatgaa cattatcatc ggcggttcca tgaaccagca ataacttgcc
    12361 ttgtaagtct ttcacccggc gtaacggaga ggtagccgca tagccctcga aattctcttg
    12421 cggggtacgc atgaaacgct ccgtataaac ggagtcataa tatttccagt ccgtcggagg
    12481 agctacagcg atacccacct taaacgttcc gtttccggta ctcaaggcca tcaacgtgtt
    12541 ataacctccg aaactccaac cccagatcgc gatacgatcc ttatcgatat aaggtaactt
    12601 gcctaacgct tgcgcagcct ccacttggtc tctggattcc agctcgccca ttctcaaata
    12661 agtacattta cggaatgcct caccacgggc accggttcca cgaccatcca cacataccac
    12721 gataatacca tttgaggcca gatattgctc ccaatcgaaa ccgtattgat ccaatacttg
    12781 ctgggagtta gggccactat attgcgtcat catcaccgga tatttcttcg acgggtcaaa
    12841 atcagcgggt tttacgatcc aagcgttgaa ctcatagtcc gaggccgtat gtaccttcat
    12901 gaactccttc ttggcaaaag catattcctt cagtttactc ttcaacgcag cgttatcttg
    12961 caggacacgt agttcctttt tggtcttcgt ctcattcact gtaatcttcg ccggggtatt
    13021 cgcgttggaa taggtattca cgaaataagc gaaattgtca ctaaagaccg ccttgttcat
    13081 accctcatcc gtggagagtt ttgtcttcac gcctttcgcg tcgatcttat agatagagcg
    13141 gcggatcggg ctttcctcgg cagactcgta atagaaagtc ttcgtattct catccacgcc
    13201 caagaacttc gtgacatccc agttcccttg agttacctga cgttgcataa cacctgtcgg
    13261 ggaatacaaa taaatatggg aatagccatc ttgttcgctc acataggtaa acccattgtt
    13321 caagaactgg atggaagtca accaatcaga atccacgtag catttatttt cctcacgcaa
    13381 gatcaaacgg aacacaccgc tcttcggatt tgcataatac atattgaata cattctgctg
    13441 gcggttcaat gtcatgatag ccaactgatc cggattctgc gtgaaagtaa tgcggggaat
    13501 atagaagtcg ccttctaccg ggaccttcat ctctttcgtg tctttggtga ctacgctata
    13561 agaatgtacg gagacctttg aattcttctg cccggccttc ggatatttat attcgtaata
    13621 ccccggataa agtccctcac catacatctg catagaatat tcgggcacct cggactcgtc
    13681 aaaacggaca aaggccagat actcgctatc gggagaccac gccattagat ttgtcaccgc
    13741 gaattcttcc tcatacaccc aatccgtgat accattcaat atcttattca actcaccgtc
    13801 cttggtaact tgtacctcgg tatcaaaatc aaacttacgt atccaaatat tattatcccg
    13861 tacataagcg cacatacgac catccggcga gaatgtcggg atcatttgct tacccttggc
    13921 atcggaaata ggcttcacat aattacgacg tacgtcataa tcataaacca cagccttggt
    13981 agagcgacga taaatagact ccgtatccct ccaaaccaag atatgatgcc cggtgctgct
    14041 gattgtatat ccatcaaaat ccgtaaaggt acattcacga gctttacggg cattaaacaa
    14101 tgtatccaca ggatttcccg tacgatagga atatttaatg atcatactct tatcggcgtt
    14161 catggctgtg tagtgttctc catccggcag ggatcgcatc tctccgatag ccgtcacttg
    14221 acgaaatttc ccatcggtta tttcttttaa gtcaacatgc ttgcttccgg tttgtgcggc
    14281 cacacttccg aatacggcca acgaaagcaa taaactaaaa cctaatcgtt tcatttatac
    14341 tctttatttc agattgaaac gcgaagttag cataaaaaag tgattcaaat tgcgagaaat
    14401 cgtatctttg tcttatgaaa aaaactaaac gatattatga atttggggat tttctacggg
    14461 atctattcaa attcaaggtt cagaagattt ccataaacgc aggcttcacc tgcccgaacc
    14521 gagacgggtc taaaggatgg ggcggttgca cctattgtaa taaccaaaca ttcagtccag
    14581 aatactgtca tacggagaaa agcgttaccg agcaattaga ggaaggcgta cgtttttttt
    14641 cccgcaaata tccggatatg cggtatctgg cctacttcca agcctacacg aatacatacg
    14701 accgattaga ctctcttatt ctcaaatatg aggaagcgct tgcctatccc ggagtagaag
    14761 gattgattgt cggcactcgt ccggactgta tgccggaagg tttattggat tattttgcgg
    14821 agctttccca gcgaaaattc gtcatgattg aatatggatt ggaaagtacg cttgataaga
    14881 ccttagtccg cataaacaga gggcataccc atgaagaatc ggaatccgct atccgtcgta
    14941 cggcggcaaa aggtatttac accggggcac acctgatact cggactaccg ggagaaagta
    15001 gggatgaaac attacaccat gcggatgtct tatcacgcct cccgatcacg acacttaaac
    15061 tgcaccaatt gcagctaatc aagaataccc gcatggcgaa agagttcaag gaagatcctt
    15121 ctgatttcca tttatatacg gctgatgaat atatcgaatt agtgattgac ttcatagaac
    15181 gactgaaccc ctctatcgta gtagagaggt tcgtatcaca atcccccaaa gagctactga
    15241 tcgcaccgga ttggggttta aagaatttcg aatttaccgc taaggtaaat aagcggatcg
    15301 aggaaagaga tacacggcaa ggacgactat ttcaagtcta aggcgacatc accataaaag
    15361 gtaatagcct gtttattcac gggtgtcaca ttgattgtca ccgagccatt cggatagact
    15421 tccacccgaa acatgtatac atcctctttg gtctttacac ggaacttgat ttcggaacta
    15481 cctttctttt cagaggtttg ctccttctct gccgccactt ctttaaacgt caagccctct
    15541 ccaccaccat aaggagcaga gtaagcacgt ccaaagtaag gaagataaga caggatcgag
    15601 tcaccatgta tttccaatga gtagggggaa gtaagattga cggatctccc ggccatcggt
    15661 acggcacgat ccacatcgat cttaatacga ccgctatcca cgatctccct cactactctc
    15721 tctttttgct ccttccgctc ttgcttactt tgagcaaaaa gggattgccc tgcacaaaaa
    15781 aggacaatcc ctaaaaatcc aactaacctt gttaatctca taaccttaat aaactaaaca
    15841 cactattaat cactctatat agtaaagaca attcttcggg tgaatagttt aatctaaaaa
    15901 ggtcaaatta aggctgttta tatttcatta tcatattaac gcaaattatc caagatataa
    15961 tcctgtacgg taaaatcttt ccgtacgatc gtatcaccgg gaacacgttc gtctgtcgtg
    16021 atcgctaaat tctcatcgcc taagacttga cggcccaaga agctcatgat atcgtattgg
    16081 ttccgggaca tagggagccc agagatctca tgccccgcat tctctacctt ataaaaataa
    16141 taggaagctt gaagattttc cagacttttc gctacagcgg atgatcccca taaaccgccg
    16201 aggttctcca tagcggcttg ttcaaaagga acggttttat ccgcatcgcc atggaatagc
    16261 ataatcggac aaggcatctt ttcccaatgt ggaggaagca caccagagac cgcaccggca
    16321 tatgagatca caccggcata gttgaaacct gccggtagcc ttttcgccaa ctcatgtccg
    16381 ttacataaat catactctgc ctgcaatacc gtaatcgccc cggcactcga accgctcgct
    16441 acgatctgct ccacatcgat gttccaatcc gagctttggt tgatcacaaa accggtagca
    16501 tcataaaaat cctctaccgc cgtatcgatc gcatgctgca aggccgcgat aaagtccatc
    16561 ggagaagaga ctttagaagg atccagattc ttcaaggtgg tacgataatc cgtagaaacg
    16621 accacaaatc cgtttcgggc gaggaactcg aaatagggaa tatatccttt atccgcctta
    16681 tctccccctt taaacccacc gccaaaagca aaaatcatca caggcttttt tgaggcgggc
    16741 gatatagaag gcaactcata cttgtccaag gacaatgtat ctgtcccttt tatagagaat
    16801 acaaaattct ctttctgaac ttccacattc gccacaggtt taggctgcgt acaagcgaac
    16861 gagcagacga tccataaagc aaatagcgaa tacacccaat ttctgttcat cttattttcg
    16921 tattagaggt tattttgttc cttccttcaa accatccaag aacttatcca ctttcttggc
    16981 agcgtctttc acgcccgctt tcattttcaa tccggcgtat gtcgcttgca atttaatgat
    17041 ctccgctttc tcatcagcgt ttaactcttc ctcgaacttg gcgtaaagat tcgtggatag
    17101 atccgagaat ttcagatccg ccttcttcca gtccttatcg gtataatcag cggcctccat
    17161 ttccacctta tctacaaaat cactaaactc cttcacatat gaatcctttg attggcaggc
    17221 gctcaaagcg aacataacca ataacatgaa tagtactttc ttcatctttt aattaaaaat
    17281 taattcgtta tacaacacaa atatatgcaa aaaggttaaa cccttgtata tgtcgtataa
    17341 ctttacgtaa tttgctatcc tattttctta atcagattaa taaatttatg gagaaaaaac
    17401 atcagtaccg aggattaacc aaacaagaag tagaagagag caggcgcctt cacggcgaga
    17461 atgtacttac cccgccccag aaagcttcgt tatggagcca attcttggag aaattcgaag
    17521 atcctattat tcgtatatta ttagtggcat ggctcttgtc catgataatc gctggcgtac
    17581 attgctgggg acctgaggcg aaaggtttta cggccttctt ggagccgatc ggcattttct
    17641 tcgctatcat gcttgccagt tgcgtgggct ttttcttcga ggtgaaagcg aacaaggcat
    17701 tcgatatctt gaatacagtc aatgatgata ttttagtgaa ggtaatccgt gacgggaata
    17761 tctgccaaat accgaaaaaa gaggtcgtcg taggcgatat cgttgttttg gagacaggtg
    17821 aggaaattcc cgcagatgga catttgcttg aagccatttc cctacagatc aacgaatcca
    17881 cactaaccgg tgaaccgatt attagcaaga caacaaacga ggcggatttc gatacggaag
    17941 cgacttatcc gtccaatgta gtcatgcgag gaacgacggt cgtggacgga catggcgtca
    18001 tgcaagtgga aaaagtgggt gatgctaccg gatacggtaa ggtctacgaa ggctcgcaaa
    18061 tcgagagcga tgtagagact cccttacaga tccaattgaa aggtttggcc ggagtgatca
    18121 gcaaagccgg atatacgatc gccggagtga cgttcatcgc cttgaccgta aaattccttt
    18181 tatcggatag cttccccggg atgccggcga tggacatcat cgcccatatc ctcaactact
    18241 ttatggtagc ggttacgttg atcgtggtat ccgttccgga aggattaccg atgagtgtca
    18301 cgctaagttt ggccctaagc atgaaccgta tgttgaagac gaataatctt gtccgcaaaa
    18361 tgcatgcctg cgagaccatg ggagcaacta ccgtaatttg tacggacaaa accggaacgt
    18421 tgacacagaa tcaaatgcaa gtctaccaaa cgaatttcta caacctgaaa gaacaaaagc
    18481 ttggggagga tgagttaagt aacctgatca aagaaggtat ctccacgaac tccacggcat
    18541 tcctcgattt ctcggaagaa aaggtaaaaa cccttggaaa cccgacggag gccgcccttt
    18601 tactctggtt gaacggacaa caccaaaatt atctggaatt aagagagaac gctacgatcc
    18661 tagatcaatt gaccttctct acggaacgga aatatatggc tacaatcgta caatcaccgt
    18721 tactcggcaa gaaggtactt tacgtgaaag gtgctcccga aatcgtactg gccaaaagta
    18781 accgggtggc gatagacgga acttgcaaac cggtggcgga atgtaaagcc ggcatcgaaa
    18841 aacaattatt ggattaccag aaccaagcga tgcgtacgct tggcttcgct taccaaatta
    18901 tcgaggatgg aaaggatgag actttcttcg tagagggtcg tttgcatgat acggatttaa
    18961 cgtatttagg tattgtagcg atctccgatc cggtacgtgc ggacgtgccg cccgctgttc
    19021 aaagttgctt gaacgcaggt atcaacgtga agatcgttac gggagataca ccgggtacgg
    19081 ccaaagaaat cggacggcag atcggtacgt ggaaaacgga tgatagcgac aggaacatta
    19141 taacaggtcc cgcattcgag gcgcttagcg accaagaggc cttggagcgt gtcttagact
    19201 tgaagatcat gtgtcgtgcc cgtcctacgg acaaacagcg tttggtacaa ttattacagc
    19261 aaaaaggcgc tgtggtagcg gttaccggcg acgggacaaa cgatgcccca gccttgaaag
    19321 ctgctcaagt cggcctctcc atgggagacg gtacttccgt cgccaaggaa gccagcgaca
    19381 tcacgattat cgataactcg ttcagtagca ttacccgtgc ggtgatgtgg ggacgttcct
    19441 tgtaccggaa tatccagaaa ttcctgttat tccaattgac catcaatgtt gccgcttgtc
    19501 tgatcgtatt attaggttcc ttattaggta cggaatcacc tttgaccatc acgcagatgt
    19561 tatgggtaaa cttgatcatg gatacattcg cagccggagc attggcctct ctcccaccga
    19621 atgaacgagt gatgaaagat aaacctcgcc ggagcggtaa ggatggagat ttcattatca
    19681 ctcgcccgat ggcttacaat attttcggtg tcggattcgc atttgtcgta atcttgatgg
    19741 gcttgttgtt ctatttccat gcgcaagacg gcttaacgcc acacgactta tcatggttct
    19801 tcagcttctt cgtgatgcta cagttctgga atatgtttaa cgcgaaggct tttatggaag
    19861 gacgttccgc tttcgccaat ttaaaggata gtaaaagttt cttgctagtt gcattactga
    19921 ttttgatcgg tcaatacctg atcgtcactt ttggaggcga gatgtttagc gtaatacctt
    19981 tgtccttgag agattgggtg attattatcg gatcttcctc tctagtttta tggatcggtg
    20041 agttattcag gttatccaaa agataaatat atattgtaca acttgtagag acgggacacg
    20101 ctccgtctct acaactgaaa atagtacacc tatataatat atcaacctag ctataaatag
    20161 ctatttcctt attccatttc gttttttaac ttcgcatccc aaattattta aatcatggaa
    20221 catctattag aattagcgaa aagaaaccaa gaaagagctt gggaagtgat ccggcaaacc
    20281 gacattataa atatctggaa atctgtcggg gcggaaataa acttagtagg ctccttaaat
    20341 atgggactac tcatgaaaca taaggatatc gacttccata tttacacctc tcccttccgt
    20401 atatccgaca gcttccaagc gatggcccgg ctagcggaga acccgctcat taaacgaatc
    20461 gaatacggaa actcgctcga tacggaagaa cgatgtgtag aatggcacgc atggttccaa
    20521 gatccgaata acgaactctg gcaaattgat atgatccata tcgtaaaagg ttcccgttat
    20581 gacggttatt tcgagaaaat ggccgaacgt ataaccgccg tactgactga cgagactcga
    20641 caggccatct taaaactgaa atatgagaca ccggatacag cgaaaatcat gggcgtggaa
    20701 tattaccaag cagtcattca agacggcgtg cgtacgtatg cagaattaga ggactggaaa
    20761 aaacaacatc cagtcacagg cgttatcgaa tggattccat aagaacatta ttgaccaaac
    20821 cgtgaagaat cgatctcttt cttattcttc cggttcatct tgcccaatgt atactttaaa
    20881 gtgagcgata ctgaacgagt atccgaatag atcgtcatat cactcttctg gctgggataa
    20941 tcaatatgcg ttttcgcacg taagcccttt aacaaatcct cacctcgcag cattacactt
    21001 aactttttcg gtatcggatt ccagataagc cctgccgata cattataatt accatccaca
    21061 tcatagatac cttgtaccga aggcgcacta tagcgagcgt taacttccag cgataagttc
    21121 ttcttctttg ataaagtaaa cgtattgaac aacatcaact gcccgaataa ctttttccga
    21181 tcaaacgaaa tatcgataaa cactccctct tcttgaatca agaagcccga tgccacgaac
    21241 cgtgagctaa ccaccccacc gatccgaaac gggataactg ccatcgcccc gaaagtatta
    21301 tgcttatcga aattaaccga ttggtaatag gctctcaacg ctttcgtatc ttgataatac
    21361 aattggcgaa tataattcac atgatgattg gcgaatagtc caaaaacata tttctttttc
    21421 aagatataat tagccctagc catataaata cgttccggtt ccaaataagg atttccccgt
    21481 acctgactat acacattcaa ataagaaaca ttcgagctca tggcccaata cgccggatac
    21541 ttcttatcgc tggaaaaatt gacttgaagc atattcgatg gatcaatcgt ataactcaag
    21601 ttcaattgtg gatagagatt tgccccagac cataaggccc atttccggcc cgccgaatca
    21661 atcaccgcct tattatactc cgccgaaaga gaagcgctca acaccagttt cttgccaaaa
    21721 cgcttagaga aaccggcata caatcccgcc gtatactctt tttctttttg ggcaaacgta
    21781 gctgacagat cctcctgttt atcttggtag gtaatggagc tattatccgt aaaggataac
    21841 tgcacattcg tgcctacgtt aattttccat ccttttccaa atacccgttc gtagttaacg
    21901 aatacattcg ccaaatggat attttgccgg gaggtagcct ccacctcttg tttcgtatcg
    21961 ggataatccg agatcatata ttgatccctg cgatccttat aataggtata atccacccct
    22021 gcgttcaagt tcttggaatg tgcataattc aaccgtacat tttgaagatt cttcgggccc
    22081 gataacttat tattactttc cgcattctca atacccacaa ataaagtgtt cgaatatcgt
    22141 ttggaattag aatccgttat cttggcataa taagaaatat ccacctcacg ccccttatcc
    22201 ataaaccaac tggcactcgc cccaatcgta tggttcatag aacgacctac cgccgtattt
    22261 tcttgcagga tctcataagg acgatccttc acgatgggat aggcgttcat atcctcggtt
    22321 gaaagggaat ggttatatcg agcggaataa gatagatcca gactatattt ctttttggag
    22381 taggataaat tcactaatcc ggttggcgag aagtagaaag cttgctttcc ggtcaaagag
    22441 atatcggcac ttaaatcctc attcactttc ttctccataa tgatatttat actacctcct
    22501 tttacgccat attttggagg agagctatac aaaagctcta tactctttac tttgctggcc
    22561 gaggtagatt tcagaagctc tacaatctgg gacaatgaca ttgagcttct acgtccgtta
    22621 ataataatgt tcgtagcagg gatgccgatg atactaacgt tgtccccttc tttcaccaat
    22681 ccgggaatct ctcctaaaat atcaaatgca gtattcaccg gtttggccat gatcaagtta
    22741 ggcacgtcga aagataaggc atcgtccgta accgtaacca aaggacgctc ggaagtaacg
    22801 tagacatccg gcaattttac cgtaatacta tctttcacca agataacaga atccttagtc
    22861 tgtgcattta cagcgacaag aacattcaga agcaacaaga aaggaacaat ggcagtcttc
    22921 ataatatcaa gattatgttt ataatccgcc aaattaaaaa gaaaaaagga gataagcaac
    22981 gaaactatcg aatatttacg aataaatcgt atacatattc aaaataaagc aattacacca
    23041 cacctactta tactattaac ccgttggcgg aattaagtaa ccgtgccaaa tcttataaag
    23101 ataaaagtca gatcaaacca aatgtgcctt tagtctgata atattcattc gaccttatcc
    23161 aaggtaaaag taaagattaa agtagaacct ccggggatac cgctataatc tccatatcca
    23221 taacctagcg aagccgggat aatcgcctcc acggtctcat ccagatggat attcaataag
    23281 acaccgctta agcccgggat aatgccgttc atagaaaaac ttgatctatc cagtttcttt
    23341 tgaaagacct gtccatctat aaacttccct tccagaccta gcaaatagac cacggaagtc
    23401 atcgtgggtg ttgttgtcca ctcattttct ttccgaatga tccggtataa ggcggtatca
    23461 ccccctagaa caacttgctt atatcttaat tcacccatct catctttctc tgttttcttt
    23521 tcccagatgt attccttgtt tttgttgata taagccaatt gttcttccga gaattgaagc
    23581 tcatcatcat ccccacaaga agtaagtccc atcatcatga tcactaaaag tgaccataca
    23641 tacattgaaa gtgctttcat tccgatttct atataaaatt aaattataat tattcttgat
    23701 ttccgaggcg cgaatataca aatccatttt gttatatcaa ctaactttcc gttctttgca
    23761 taaatatagt agtaaccaac taatacaaca tgaaactaaa taaattaata gcgatcgcca
    23821 cgatcagcct tctgtcggga ggtataagca tggcacaaaa agcgttgaat cttgaggata
    23881 tcgttgccgg taacgtcata caaacaaaag gcatcggaag catgacttgg ctaaaagacg
    23941 gtgaacgtta tagccgcttg gaaaataata agcaaaccgg aggcacggat atcgtcgcct
    24001 atcaagcaaa agataactcc cgtgaagtca ttatcccctc atccctattg acagacaaat
    24061 ctacaggaaa gcctattccc gcacgtagta tctcttggag tgcggataat aagaaagtct
    24121 tgatttataa caatacccaa cgggtatggc gttatgatac ccggggtgac tattgggtat
    24181 taaacctaaa ggacggcgct ttacgtcaat tgggaaaagg aatgccggaa tcctccatga
    24241 tgttcgctaa attctctccg gatggcacac gtgtggccta tgtttccaac aataatatat
    24301 atgtagaaga tatagactcc gggaaaatca cgcagctaac aaaagacgga agcgatacga
    24361 ttgtcaacgg aactttcgat tgggtatatg aggaggagtt cagttgccgg gatggtttcc
    24421 gctggagccc ggacggaaag catatcgcct attggcaaag cgatacgaaa ggaacgggag
    24481 tgttcgacat tattaataat gtagactcca tctacgcaaa ggtaatccat ttcccatacc
    24541 ccaaggcagg aaccaccaat tcagccgtaa aagtaggcta cgtttcctct accggcggga
    24601 acaccacttg gatcgccata cccggagatc cccggaacaa ctacctgccc cgtatggaat
    24661 tcatccccga aagcgacgag ttgttcatac agcaactaaa ccgcccgcag aatacaaata
    24721 aggtatggat cgccaagata tccgataact cgctgaataa tatcttcact gatacggatg
    24781 ccgcatggct ggacacgaat gataacatac aatggttaaa ggacaaccgc tatttcacat
    24841 gggaaagcga gcgtagtggc tggcgacact tataccggat aagccgggac ggaaaagaga
    24901 tacaacccat caccaaaggt gattttgatt atatctcgcc ggtcgggacc gatctacaaa
    24961 agggctgggt ctatttcatc gcctccccgg acaatttcac ccaacgttac ttgtaccggg
    25021 ctaaagcatt cggcaatggg gaagtggagc gtgtaagccc catggaacaa tccggacagc
    25081 accgctacaa tatgtcaccc accggcaaat gggccataca tacgtatagt aacgcctcta
    25141 ccccatccgt tatcgacatg gtttctttcc cgaaacatca atccgtacgc atgcttgagg
    25201 ataatgccca agccaaggac caatacgccg ccttaggatt aaacccgaaa gaatttatca
    25261 aggtcaagtc cggcaatcta accttggacg catggatgat aaaacctgtc gatttcgacg
    25321 catccaagaa atacccggtt atcatagagg tatacggcga gccggcgagc gccaccgtac
    25381 aagatgtatg gggtaacgga gatttatggc aacaatatat ggcgaaccaa ggttatatcg
    25441 tggtaagtat cgagaaccgg ggtgcgaata ctccccgtgg acgtgaatgg cggaaatgta
    25501 tttacgggga agtgggtact ttcgcttccg aagaccagag caggggtatt ctggatatga
    25561 cccgtcaata tccgtttatc gatgccaaca ggatcggtat taccggatgg agcggtggtg
    25621 gtagccagac cttaaactgc atgttccgtt atccgaaaat attccatact ggtatagcga
    25681 tcgcttttgt agccgaccaa cgtttatacg acacgatcta ccaagaacgt tacatgaata
    25741 ctccgcagaa caatccggaa ggctaccaca aaggttcccc gattacctat gccgagggac
    25801 tggaaggtaa tctgctgctt attcatggta cgggagatga taacgtgcat taccaaaatt
    25861 gcgagatgct ggtgaacaag ttgatcaaga acggaaagat gtttacgcaa atcagttacc
    25921 cgatgcgtag ccatagcatc aacgaaaggg aaggaacaac tcttcaccta cgtaagacaa
    25981 tggctaaata ctggctggaa catcttccgg ccggtggtaa atagttaatc cacgattcga
    26041 tgaaacaatt tttattgcga ttagtgatct tggcaggaat cagtttcctg ccaacggtgt
    26101 ccaacgccca attaagggaa aaggccgaag aactattgtc tacgacatta ggcaatgatc
    26161 cggaggaacc agttacccca accgatacgc tttcgctcga tgagcagcac cggaaggatt
    26221 ccatcaagat gcaggagcta gccctccagt tgcaagagat gaaactaaac gagatcttac
    26281 tgaaagacga gctggaaagc acgaaaaaca gcaacgctac cgccgactcc ctaaaaaggt
    26341 ccgagcaacg aaaccgtatc gattcccttc gggcactgac tcccggcgta cctgtagtcg
    26401 tggaggggga taccttattt cacctttacg ccaagcgcgg aggccgcacc ccggttgacc
    26461 gggctgagga catcctcaat atcatggtaa agatcgggac ctcgcattcc ttgaagaagg
    26521 attccatcta tatctatgac agcgaatacg taacggatat catgtacgga gacaaggtta
    26581 tcctaagtat caccgatcaa gatgccctat ggcaaaatct cagtcgtata gccctcgctg
    26641 aacaatatca accgattatc caaaacaaga tacaagagtt aagggagcaa catagtatct
    26701 tgcagatagc gaaacgggta ttattgttca tcctcgtaat tatcatccaa tatttcctgt
    26761 ttaagctgac caactatctg tttaagaagc tacgcaggaa aattatctgg ttaaagcaga
    26821 accgactcag atctattacc atccgggatt atgaatttct caacacacat cgccaaggac
    26881 gtgtattgat gtttttcacc aacgtaatac gatggatcgt gttactaatc caattaacca
    26941 tcagtgtacc gatccttttc gctatcttcc cgcaaacaga agatctagcc ttgaagatat
    27001 tctcctattt gttggagccg gtaaagatga tctttaaatc ggtagcctcc tatattccga
    27061 acttgtttat catcttggtg atctattact gcatcaaata catcgtaaaa ggaatccaat
    27121 acatagccaa cgagatagag agcgagaacc tgaaaatatc aggtttttac ccggattggg
    27181 cgcaaccgac gtttaatatc atccgtttcc tgctatacgc ctttatgatc gccatgatct
    27241 atccttatct gccgggatcg gactcggggg tatttcaagg catatccgta tttgtcggtt
    27301 tgatcatatc gttgggttcc agtacggtga tcggaaatat catcgcaggg ctggtcatta
    27361 cttatatgag gccctttaaa ttgggtgacc gtatccaact aaacgagacg actggcaacg
    27421 tgatcgagaa gactccgttt gtaacccgtt tacgtacccc taagaatgag gtagtgacca
    27481 tcccgaactc ctttatcatg tcctcccata caacaaatta tagcgtatcc gcacggcaat
    27541 acggattaat catccacagc acggttacga tcggctacga cgtaccttgg cggcaagttc
    27601 atcaattatt gatcaatgcc gcccgccaga ccaccggggt attgccagag ccgaagcctt
    27661 tcgtattgga gaccgaacta agcgattact atccctgtta tcaaatcaac gcttatataa
    27721 aggacgccga taaactcgga gatatctatt ccgacctgca tcaaaacata caggacgtat
    27781 tcaatgaggc tggcgtagag atcatgtcac cgcactattt cgccggacga gacggaagcg
    27841 cttccacgat cccgaccgct ccctatccgg atgactgggt agagccttcc aagaaataaa
    27901 tatttcacgg taaatagtta aaaatgatcc ctcacgaaac aaatcgtggg ggattttatg
    27961 ttatatgtcc aaacgtcact aataaaataa ataatggtaa tgaaaaagta ttttatcgca
    28021 gtagcggcta tggcattttt ggccgcatgt agcgggaagc aagcccaaaa ggatgtaccc
    28081 gtagaagtag aggaagaaga attcgccata atgtcggcgg ctccggacgc tccgtctttg
    28141 ccactgatcc attctgttaa ggcgacccaa ccggcaaagc ccgtgaatat gagggattcc
    28201 ttgaaggctg atcctaaaaa gggaccggtt atccaaaaaa agtataaggg aaccctgact
    28261 tctccggata gcgtgaacgt agattatgac ttaaccttgt attatcaaca agataacgca
    28321 gacgaggaag gcgtattcga gttggatgct ctttataccg taccggaagc agtagcctca
    28381 agtaccggag cggcgaagaa agctcctcag aaagccatta caaccggtaa acaaaaagta
    28441 aagcacggaa ctcccgatga cgctagcgca gtaatctacg agttgattcc cagtgatggc
    28501 gaacccgtca tctatttcct agtagaaggg gataacttga ccttgatgaa cgacgcgttg
    28561 caaaaagcgg cggcagatct taactacacg ctaagacttg tccaataaat ttataggcag
    28621 cacatctttg tatatataga tcaccccgat agacttaccg gatcgccgga agctatcggg
    28681 gtttagtttt tatttgaacc ctccttggca gatcggttat ttgataccta acttggcttt
    28741 gatcgcttta ggcaaggcat ctttatgaac cacgatattc atggtcttat aacggacaaa
    28801 cgccttggaa gcataccaaa taccgttata cttgctgttg gttccccaag agttctttac
    28861 catataatac tcgttcccct cttgatcctt ggcgataccg tagatctgca taccatggtc
    28921 gtctgtcgtc tcgtaattat cgtaagccaa ctgacgctct gcttgggtac accatttctg
    28981 aggttgcggt tttgtgttca gcttcttttc ctccggtttc aatttcaacc aatgagccat
    29041 atcggaaccg ctcaactcct gtaccttctc atcatcaggc ataacggcca ctccgtcacg
    29101 agtaaaacca gattcgctca catcggaacc ccaagcgatc gtataacccg tattaatcgc
    29161 attatcaaag acctccataa actcatccag cggcaagtta tacgacatac cgtgacgcca
    29221 gttatcctga atctctagcg ggaactgggt atagaacgga tgatgcgtat aagaagtcaa
    29281 tgagacataa tccgaagcct tcaaacctgt agactcgaag aaagatttcg gtgtatattc
    29341 cttcccttta tacgtgaatt tctcaggagg aacccccaag tagatctgat gtaccgcagc
    29401 gaccgccttc ttccataaca tggcgttatt ctcatcagac tgcaatttgc gtaactttcc
    29461 cttggcgata gcggccacca tagcgtccgt caaggcggaa agctcggtat ggttactcaa
    29521 cgtatcggca tacatcatgc ccgggcgcat ctcctcttcc ggaaccaagc cgaatgtttc
    29581 cattccataa agcgcatcat agaaagatcc accttgcgag aacgaaacat ccccatgcgt
    29641 acgcacagca gcgtcggcac gatccagata ggtgttatat accgtaaaca tctcggataa
    29701 gtcatactcg ccctttccca tacgaagcaa ctccgactcc aagaaagagt acgaggagta
    29761 gcaccagcac gtacccgcac gattttggtt cttaacagat gtaatggggt tctctttcac
    29821 ggtcgtgaac acgaatccct cctcactcac cttcttctcc gtgtcttgcg cttggatcgt
    29881 agcggacata gtcagagcga atagcatgct tgaaactaga attgtctttt tcatgtaatt
    29941 ttatatattt atattagtat taagtccgta tcgaccgcaa atgtaagttt tttatccgta
    30001 gctaactcta caaagtcgta cgtatttgag atattttatc taagtttgcc tcttcagaaa
    30061 acataatata taactaatta tctgcaaaat gagaatatct attatcggtt cgggtaatat
    30121 cggtggagcg atcgcccgag gtttagcgaa aggaaccatg ttcaaagcct ctgatatcac
    30181 ttgtaccgcc caatcggacg agaccttgga gaagatgaga aagatcgatc cggactttat
    30241 cttgacccat gataacgtgg aagcggcacg aaacgctgat atcatcatca tcgccgttaa
    30301 accttggcgt gtagaaatga ttatagatga gattaagtcg gtgctcgact tcgagaaaca
    30361 aatcatcgta tccgtagcgg ctggcgtgac tttcgacctg ttgaatactt atttgaccaa
    30421 gaatacagac ttcgattgtc tggctactcc cacgatcttc cggatcatgc ccaacacggc
    30481 tatcgaggtg atgagcagca tgactttcgt ttccgcccgc aacgcctcca aggagcaaac
    30541 ggatctaatc atccatatct tcaacgagct tggcaacgcc atgttggtag aagaacggtt
    30601 gatgggcgca ggaacagcat tggcttccag cggcatcgct ttcgccttgc gttatatccg
    30661 cgcggcgata gaaggcggcg tggaattggg tttctatccg aaacaagcgc aagagatcgt
    30721 ggtgcatacc gtgaaaggcg ccgttgattt attgctcgag aacaaaagta acccggagat
    30781 ggaaatcgat aaggtaacaa ctccgggcgg aatcacgatc aagggtctaa atgagatgga
    30841 actttccggt tttacctctt ccgtgatccg gggactgaag gccagtaaat aaaaataggc
    30901 agacaaagta gtttgccagc accaatacgc cccgaaatat gctgacaaac tactttacct
    30961 gccctcggca ggtttatgtt ctttccgcct agtcatttcc atctccaaca tccggagttc
    31021 ccggctggtc tgccccgcga cagaagtatt ctcttccgca cgccggatca aatacggcag
    31081 tacatccctt accgaggcgt acggtacgta tttggttacg ttatatcccg catgggctaa
    31141 attgaaggaa atattatcgc tcattcccaa tagctgcgca aagaaaacac gggagtcatc
    31201 gcgggcgatc cccttctcgt ccatcaattt cgccaactta taattactct cctcattatg
    31261 agttcccata aacatctcaa aacgatctaa atgatccatg gtgaaacgga ccgccgcatc
    31321 ataattctcg tccgtggcct gcttatcttt acaaatcgga tcgggataat ccaacgccgc
    31381 cgcacgggca cgctccgctt ccatataagc cccgcgcacg aatttcacgc ccgcaatata
    31441 acctttcgcc acggcatcat cgtagatacg acgcagataa ggcatccggt catgacgata
    31501 catttgcaag gtagcgaata cgatcgcacg tttcttgttg aacttacgca tcgcctcatc
    31561 ggtcaacgca tcaatggcat cttggaaaca ataatcctcc gcatccacta aaatacgtac
    31621 gtcgttatcg taagcccgtt ggcaaagcgc cataaaacgc tcgcggaact cgcggaaatg
    31681 ccggacatcg tctatcgtaa gctcttcccg tttctcggaa gctttggcca gtaactcatc
    31741 ggtcgtgatc gtggatggtt tgaatacggc ataggccaga ttcgtatttc ctttcgcaaa
    31801 atctatcgag cgcaaggttt cctcgaaagt cgcctgtatg ccctccgggg tctgctcgct
    31861 ctccgccgaa taatcgagcg tcgatttcac gttgtatttc atcaagtggt tgatggctgc
    31921 ggaacagtct tgtaaagttt ctcccccaac gaactgttta tataaggtag gcttcaccgc
    31981 ccaagccagc gggaaatgta ttttcaaggc tatactcgtg gctactttag cgcattttac
    32041 caaccaagga tattttatcg tattaaaaag ccagtaagca ttttgtagtt ctccccgcga
    32101 cttcgacgag aaagcgatct cggtattgtt aaagtctaac atattgtatg tagataaagg
    32161 taacgtcata gcgtagagac ggggcacgcc ccgtctcccc cacaatcagt tggtatttct
    32221 taattatgac aattatttct cacctaagaa cggatacccg tagctcgtcg gaggaaccaa
    32281 acattccttg atacaacgag gattcgtcca acgaatcaag ttcagcgggc caccggcctt
    32341 gtcattcgtt ccggacgcac gggaaccgcc gaacggttgc tgggcgatca cggcgccggt
    32401 cggtttatca ttgatataga aattaccggc cgaatagcgc aaggtattga atgccttatc
    32461 gatcgcatag cgatcacggg cgaaaataga acccgtcaat ccgtacggag aagtacgatc
    32521 acaaagttcc aaagtctcct catatttagc gtcgtcatat acgtagatcg taatcaccgg
    32581 cccgaagatt tcctctacca tgctcttgaa catcgggtcc gtggtctgga taaccgttgg
    32641 ctccacgaaa taacctacag atttgtcccc gttaccacca aaaagaacct ctgcgtccgg
    32701 agactgtttc gcataatcga tataactcat gatgttatcg aacgaagcct catcgatcac
    32761 ggcattgaca aagttcgtga aatcctgcac gtcacccatc ttgatctctt tcagcatatc
    32821 gcccacgtaa tctttcaact ctttccagag agaagccggg atataggccc gggaacccgc
    32881 cgagcacttc tgcccctgat actcgaacgc gccgcgtacg atagcggtag ccacatccaa
    32941 cgccggagcg gaaggatgag cgaagataaa gttcttgcca cctgtctcgc ctacgatctt
    33001 cggataagat ttataatgcc ccaagttctc tccgatctga cgccacaagg tattgaacgt
    33061 agaggtagag cccgtaaaat ggaatcccgc caaatcacgg ctacccgtaa tcaccttacc
    33121 gatcacgcta ccctgtcccg ggatgaaatt cactacgcca tcgggcaagc cggcctcttg
    33181 gaaaaccttc atcaagaaat agttcgaatg gatcgccgta gtagacggtt tccataccgc
    33241 cacgttaccc atcatagccg gagccatatt caggttggaa gcgatcgacg taaaattaaa
    33301 cggcgtgagc gagaacacga aaccttccaa ggctcggtat tccatacgat tcaatatacc
    33361 cgtctcggaa tagggttgat cggcatatac ttgactagcg tagaaggtac tgaaacgcaa
    33421 gaaatcgatc aattcgcagg gagcgtcgat ctccgcttgg aacggattct tgctctgtcc
    33481 caacataacc gaagcgttca ggatataacg atatttcgta gccaacaact cagctacacg
    33541 aagcataata gacgcacgtt ccacccatgg aagttctgac cattccttat gcgctttcat
    33601 ggcggcgtcg atagccattt gtacttcttt ctcgcccgcc ttatgataag tagccaatac
    33661 atgatgatga tcatgaggca taacgacctt accggtatta cccgtacgga tctcttttcc
    33721 gccaattacc agaggtatat cccattcctc ggaacttatc tgcgccaacg ctttctttaa
    33781 ggatgctttt tcacttgatc cgggagcata cgcttttacc ggctcattaa tgggtttagg
    33841 aaatctaaaa atagcattat ccataatact tcagattttt taaatggtta ttcaatgaaa
    33901 ctttctgctg taaacgtagc aaatttattt taaaacagtg gcgtgtaaac gttaatatat
    33961 atcaaccaaa gataagctca tttcacggtc tatacaatga tctaaaagac ctctcccgaa
    34021 aacaatccgc gaaagttgtt tgttacatta acatattaat catcttaaag gaataaaatt
    34081 atggcaatta aaagagtttg gattgaagag gattgcatcg cttgcggtac atgcgagggc
    34141 atttgcccgg aagtattcac tgttacagat cgttcacgtg taaacgaagg agttaatttc
    34201 gatgatttcg aggcgggtat taaagaggct gccgaaagct gcccggtcga ggttatcaaa
    34261 tacgaataga cgaaaacaca ttaaccctta cttttccttc ctagataaaa tcacagaatc
    34321 attgcgcgat ctataataac acgttacctt tgcggaggta aggttaataa cattaacttc
    34381 ttacgggaat agaaagaatc aaaataagaa ataagaagta aaatgagaaa attagtatta
    34441 ctgagttttg ttattgtcgc ctctttgcaa ttttgcgggg cgcaatcatt agataagatg
    34501 caatggttca acgagccgga gcaatgggag attaaagaca agtcactttc catgcaggtc
    34561 actccccaaa gtgactattg gaggatttcc cattacgggt ttacggtaga tgacgctcct
    34621 ttttattatg cgacttatgg gggtgaattc gaagtgaaag tcaagataac cggcgattac
    34681 aagcagcgtt ttgaccaagc cggcctgatg cttcgcatca atcatgaaaa ttatataaaa
    34741 gccggtatag agttcgtgga tggtaaatac aacctaagcg cggtcgttac gcataagacc
    34801 tccgactgga gcgttatcac cttagacaaa gcgatccctt atgtatggat aaaagctgtc
    34861 cggagattgg acgccgtgga gatcttctac tcattcgatg ataaggaata cacccttatg
    34921 cgtaacgctt ggctacaaga caatatcccc gtacaagtcg ggtttatggc cgcttgtccc
    34981 gacgggaaag gatttaatgt gacattcgag catttcaagg taaaacacct cccggatcag
    35041 cgccggttag aatggctaaa gaaaaatgcc gaatagctta taattgccgg acatatcatg
    35101 tatgccctta tcaaggatca tgaggtgaag gagattatat tgatgaggta atcctatcta
    35161 tttgcttaaa ttaatggaat aattctgaca catctctttt taaaaagggc tcaatcagat
    35221 actagaagat ggtaaaaagc acgtttgaag gccattttcc actcaaaaag ccttgctttt
    35281 tcacacggat accggcgtaa agtgatgcga ctagcggcgt tatcccatac aataggagac
    35341 gtaaagcgat acatttagtc tcatgaagcg atataaccgt atgtaaatac gctccgatcc
    35401 ggataaaaac aaggcttgcg ctctaataaa tatgaactag gatgaattcc ttcagctaga
    35461 ataaacaccc ttttttcgat aataatcaag ggaacaagta gttgctgtta ttttttcccg
    35521 tttttagcaa caaggtgtac ctccgtccgg aatatgcgac tctccggcac ttgagtttac
    35581 aaaatgtcaa aatgataatc gcccatatat ataaatcacc attctccatc cggaagcaaa
    35641 tgaagcgcct attcattata atcctcaacc atcctatcca tacctgttaa ttagaaaaga
    35701 aaacaagggc tttcaccttc tttttgcttt ttattcctat ctttggagcg acataataca
    35761 ataacttcag caaaatgaac gaacagatac aacaaatcgc agagcgtctg gccggattac
    35821 gggacgcact ggagattacg ccggaagaaa tggcaaaggt ctgcaacctc acgactgagc
    35881 aatatttgct gctggaaagc ggcacggttg atatttccgt tagcgtattg caccagatct
    35941 cacaggctta tggcgtagaa ttaaccacgt tgatgtttgg cgacgagcct aaaatgagta
    36001 cgtactttat tactcgtaac ggaaaaggtg ttgccgtaga gcgtacgaaa gcctataagt
    36061 accaatcatt ggccgccggt ttcgtcggac gtaaagcgga ccccttcttg gtaaccgtac
    36121 atcccaaacc agaggatgag ccgatgtatc tcaattccca tccggggcaa gaatacaata
    36181 tggtattaaa aggacgtctg ttactacaga tcaacaataa agatcttatc ttagaagaag
    36241 gtgatagtat ttattttaac tcagagcttc ctcacggtat gaaagcgctg gatggggaaa
    36301 aggtcagttt cttggccgtc attttataaa cgatcaacag catgttagaa agatttatag
    36361 ataaaacgac gtttgagtcg caagaagatt ttattaaaaa cttcaagatc aaggttccgg
    36421 agaacttcaa cttcggatat gatgtggtag acgcttgggc ggaggaagaa cctgataaga
    36481 aagcgttatg ttggacaaac gatcatggag agcatattga ttttacgttt gccgacttga
    36541 aacggtatac ggaccagacg gcttcttatt tccaatcctt ggggatcgga catggcgata
    36601 tggtgatgct gatactcaaa cgccgttatg agttctggtt ctctatcatc gcattgcata
    36661 aattaggggc tgtcgtgata ccggctacac acttactgac caagaaagat atcgtttatc
    36721 gtgcgaatgc cgccgatatc aagatgatcg tttgcgccgg agaggaagtg ataacgaaac
    36781 atatcataga ggctttgccg gactcaccga ccgtaaaaag tgttgtatcc gtagggccgg
    36841 aaataccgga aggtttcgag gatttccaac agggtatcca aaacgccgct cctttcgtcc
    36901 gcccgtctca cccaaatagc aatgacgata tctctttgat gtatttcacc tccggtacga
    36961 ctggaaaccc gaaaatggtg gcccacgact ttacgtatcc gctggggcat atcgtgaccg
    37021 gtagtttctg gcacaacttg cataaggaca gccttcacct gacgatcgcg gatacgggct
    37081 ggggcaaggc agtttggggt aagctatatg ggcaatggat cgccggagcg accgtatttg
    37141 tttacgacca cgagaaattc acgcctgctg atatgttgca gatgatacag gattaccgga
    37201 tcacctcgct ttgcgctcct cctacgatct tccgtttctt aattcgtgag gatatgacta
    37261 aatacgattt atcatcttta caatattgta cgatcgccgg cgaggccttg aaccccgccg
    37321 tgttcgacac gttctataag ttgaccggca ttaaattgat ggaaggcttc ggccagacag
    37381 agactacgct gacagtcgcc actttcccgt ggatggagcc gaaaccgggc tctatgggtg
    37441 ttcccaaccc gcagtacgat gtcgatttat tgcgtccgga cggaagccgt gcggaggatg
    37501 gcgagcaagg acagatcgtg atccacacaa caaatggcaa gcctatcggg ttattcaagg
    37561 aatattaccg ggacgcagaa cgtacccggg aagcttggca cgatggcctg tattacacgg
    37621 gagacgtggc ttggcgtgac gaggatggtt acttatggtt cgttggccgc gcggacgacg
    37681 tgatcaagag ttccggctat cgtatcgggc cgttcgaggt ggaaagtgcc ttgatgactc
    37741 accctgcggt agtggaatgt gctatcaccg gtgtccccga cgagatccgc ggacaggtag
    37801 taaaggccac gatcgtattg gcgaaggatt ataaggataa agcgggtgat gccttggtca
    37861 aagaattgca aaatcacgtg aaacgtgtca ccgctcctta caaatatccc cgtgttgtcg
    37921 aattcgtgga cgaactgccg aaaacaatca gcggaaagat ccgacgggta gagatccggg
    37981 ataaagataa taaataataa atcataactt tcttgaaaag gatcgctgta aaaataggaa
    38041 gcaatgtcct gacccgcaag gatgggacgc tagatatcac ccgcatgtcc gcgttggttg
    38101 accaagtagc ggacttgcac cggcaaggta tggagatcgt cttgatctcc tccggtgccg
    38161 tggcttctgg acgaagcgag ataaaggccg gcaaaaagct ggatcccgta tcagcccggc
    38221 aactgtattc ggcggtagga caggccaagt tgatcaaccg gtattacgag ttattccggg
    38281 agcatggcat gacttgcggg caagtgctta ctacaaaaga gaatttcggg agtcgtacgc
    38341 attacctgaa ccagaagcat tgcatggagg taatgcttga aaacaaggtg atccccatcg
    38401 taaatgagaa tgatacgata tccgtaaccg agctgatgtt cacggataat gatgagttat
    38461 ccggcttgat cgctacgatg atgggaatgg atgccttggt gattctcagt aatatagacg
    38521 ggatttacaa tggaaatccg tcggacccgg atagttccgt gatccgggaa atcgaatgtg
    38581 ggaaaacaga tttgtcggaa tatgtacaga ctagcaaatc atcctttgga cggggaggta
    38641 tgttgacgaa atgtcatatc gcccaaaaag tggcggacga aggtattgcg gttatcatcg
    38701 ccaacggcaa aaaggataat atccttccga tgttattggc ggtggatagc gacacggtct
    38761 gcacccgttt cattccggcc tcgaaacccg tcagcagcgt aaagaaatgg atcgcccact
    38821 ccgagggttt cgccaaaggg gaaatacata tcaataaagg agccgaggag gcattgaccg
    38881 ccccgaaagc gactagcgta ttattggttg gagtaacccg catcgagggt gatttcgaaa
    38941 aagatgatat cgtaaagata atgaatgagg aaggcgtgca aatcggcgta ggctgtaccg
    39001 cctatgacag cgaggaagca cgtaagcaaa tagggcaacg ggatttaaaa ccgcttatac
    39061 attatgatta tctatatctg gattaaaaag tatgaatgta aaagatatgc tgcgacaggc
    39121 atcggatgcg gctaaacaat tgataacgct atcggatcaa acgattatcg ggatcttaaa
    39181 ggagacagcg caggttctac ggactcatac ggaggaggta ctcgccgcga atcgccaaga
    39241 tctggaacgt atggacccag cgaacccgaa atacgaccgg ctgaaattaa cagaggaaag
    39301 gctacaaggt atcgccgccg atatggagaa tgtatcgaca ttaccttctc cattaaataa
    39361 ggtcttgagt gagactatcc gcccgaacgg aatggttatc cgaaaagtaa ccgtgccttt
    39421 cggggtgatc ggcgtgatct atgaggctcg tccgaatgtt accttcgatg ttttttcctt
    39481 atgtttccga agcggtaatg tttgcgtact aaagggtgga tcggatgcgg acttctctaa
    39541 ccgagccttg gtacgcatca tccattctgt attggagcgt cagggtataa atccggctgt
    39601 atgcacttta ctacctccgg atcgagaggc tacggcggaa ttactgggag cggtcggctt
    39661 ggttgactta atcattcctc gtggaagcag ttccttgatt cactttgtcc gggaacatgc
    39721 gaaagttccg gtgatcgaga ctggcgctgg tatctgtcat acctattttg atcgctccgg
    39781 agataaaggc aagggacgtg agatcgtaaa taacgcaaag acacggaggg tcagcgtatg
    39841 taatgccttg gattgcttaa tcatccaccg agaacgtcta tctgatcttc cgtatatctg
    39901 tggaaagctt ccggacagca acgtaatcat ttatgcggac gaaccggctt atgccgctct
    39961 atccgaacat tatccggaga cgcttttaca acacgctaac gaaaaaagtt tcggtaccga
    40021 gttcctcgat tacaaaatga gtatccgtac cgtatcctct ttagacgagg ctctatcaca
    40081 tatcgcccgg tacagttcaa aacatagcga aagcataatc agcgaagatc cggaaactat
    40141 ccggcgcttc cagcaattgg tagatgccgc ttgcgtatac gcaaatgtat ctaccgcctt
    40201 tactgatggg gcccaattcg gattcggggc ggagatcgga atcagtaccc aaaagctaca
    40261 tgcccgggga ccgatggcgc ttcctgaatt aacgacttat aaatacatca tagaaggaga
    40321 cgggcagacg agaatatagg aactcgcctg tctctttctt ctagaacaac acttaaatct
    40381 aaacgaataa tgtcaacagt aatagattca aatattttca atactttagt ttcaaataca
    40441 ttctattcct gtcctttagg aggggctatc tatgatacgg aaggaaatct gatagacttg
    40501 aataaggcga tgttcgctca tttttccttg gcggataagc atgactttat tatagaacat
    40561 ctatttaata acatcgtact aaccgattcc ttgaagtcat ctttaagaaa aggtgacgca
    40621 attatatgcg aagagcccgt cacgtttaaa gtagaaccca tctataccga tgaacagggg
    40681 cttagcgggt atacgctttg gcttacgcag cagggagaaa aagaaactga cagggaaaat
    40741 aaactattga tgggacaatt gaacgagagc cggatattga tgcggcaagc gttggaagac
    40801 ggtaaattag ctgcttactc attcagcttc gaccgtttct ccacttgcga caaaaagcat
    40861 tgtaaccgct gttttcaatt ctacggcacg accaatactc tattagataa aaacaggttt
    40921 atatgcaggg ctttatcatc cgtacgtaag cccgaggata gtttggattt cttctatctg
    40981 ttcaataaaa tccgggacga gaaattatcg tctcacaacg tcaccttcca cctgaggaat
    41041 caagacggga cttataagat gtatgaaata tcgggtaaaa gcatggatat tgatgaaagc
    41101 ggcaccccac atgtcattat aggtagcatt atcgaaaagg aaaacgacga gctagctatc
    41161 gcagatcatc agaaatccaa ggatctttcc ctattgaaat ctacgtttct ggcaaatatg
    41221 acgcacgaga tccggactcc gctaaatgcc atcgtcggct tctccgatat gttaggactg
    41281 gaagatgatc cggaaatgcg tgaacagtat atttccatga ttaaagaaaa taacacggct
    41341 ttgctcgaat taatcaatga cacgctcgag atgtccagaa tcgagtccaa tacgatcaat
    41401 tggtcatatg aggatgtaaa tccgctcgct atcatgcacg atgtatacga atacgcctct
    41461 ccccgcatat ccgaaaacgt acggttaatc ttggatgatt ctccaaacgt atctcttcac
    41521 acggataaac ataagcttat gcttatcttg aaaaaactac tttctaacgc cccccgatat
    41581 acggagaaag gagaaattca tttcggatac caatcgttgt atccggtcag cgtgcaattt
    41641 tacgtgtccg atacaggtaa cggcatcccg aaggacaaac tgggacatat cttcgaacga
    41701 ttcgtgcaat tgaacgaatt ccagccgggc accgggttag ggctttcgat ctgtaaaggt
    41761 ctggtcaccg ccatgggagg taccatctgg gtgaactcgg aggaagggaa aggttctacc
    41821 ttcagtttca aactacccat aacacctccg gatacgatct cttaaacaat tccttggtct
    41881 ttctaaagga taattgacaa gtagtcatta tctttgcctt taacaaaata ttattgtaac
    41941 agatatgaga catttcactt gcgtacagga tttaggtgac ttgaaacaag cgcttaatga
    42001 agctttcgag atcaagaaag atcgtttcca gtttagtgaa ctgggaaaaa acaagacgtt
    42061 gttgatgata tttttcaact caagcctacg tacccgctta agcacccaaa aggctgccat
    42121 gaacttaggt atgaacacga tcgttttgga cgttaaccaa ggtgcatgga agctggaaac
    42181 agagcgaggt gttatcatgg atggtgataa accggagcat ttgctggaag ctgttcctgt
    42241 aatgggctgt tactgcgatg tgatcggggt ccgttctttc gcacgctttg agaataaaga
    42301 agatgattat aacgaaaaga tattgagtca gttcatcgag cattccgacc ggccggtatt
    42361 tagcatggaa gcggcgacac gccatccgtt gcaaagtttc gccgacttga tcacgataga
    42421 ggaatataag aaaacagctc gtccgaaggt agtcatgact tgggctcctc atccgaaatc
    42481 attgccgcaa gccgttccaa acagctttgc cgaatggatg aacgctacag attatgagtt
    42541 tgttatcact catccggaag gttatgagct tgatcctaga ttcgtaggca acgctaaagt
    42601 ggaatacgat cagaagaagg cttttgaagg agcggatttc atttacgcaa agaactggtc
    42661 cgcttataaa gatccgaatt acggacaagt aatcagcaca gatcgtagct ggaccgtaga
    42721 cgcagagaaa atggtactta cgaataacgc ttatttcatg cattgcttgc cggttcgtcg
    42781 caatatgatc gttaccgatg acgtgataga gagtccgcaa agtatcgtaa tccccgaggc
    42841 cgcgaaccgt gagatctccg cgcaaaccgt attgaagaaa atattgatgg gattatctaa
    42901 tctttaggat agagagatag ggtattcttt acgatgggca ttctcaggtg tttataacag
    42961 gcattcttaa caccttagaa tgcccattgt aagcatctaa gaataggcat caaggttttt
    43021 caatgtaaac gagccatccc aacaataaaa gagtactccc ctactcttgt agaaaagtac
    43081 tctttctatg gctgaaaaca aatctattaa gcctctcctg tcggacctgc gaagtcctca
    43141 aaattagctg ttttgttatt attatttcct gcttgaagtt gctccccaaa tttcttgata
    43201 ttgtcttgca aagcgaataa caaacgttga gcgttatccg gagttaagat tacgcgactt
    43261 ttgacttgtg ccttaggagc tcccggaacc acccggatga aatctaggat aaattcagag
    43321 cttgaatgag atataatagc caaattggcg taagtccctt gtgccatttc ttcagataac
    43381 tcgatctgaa tctcgttatt ggcaggtttg ttgttttcca tactttcttc ttttaaattt
    43441 atggtgatta aaaattgcga agacaaatat acatatttat tccgggttac aaaggggttg
    43501 aagactataa atgcaaaaac gactaccttc tcaggcagtc gttttctagt tgtgttttta
    43561 attctcaatt ctttagacca atgtaaaaat accttttgtg tttgatataa ttggttttgg
    43621 cgttttagtt aaggtttgtt ttgtctaagt gctaatctct ttcacttgaa ctttacaaaa
    43681 gtaagggctt tagcaaagac cactaaatac tatatgtgca ataaataata ctatatcatc
    43741 aacacttgac acaaatcaat gtaaacatgc tttaaatcat gttttaaatt ataaacctcg
    43801 aacgggaata tttctccctg tactctgtag gggtactccc cctacgccgt ttgaataccc
    43861 ggttgaaatt cgatagatta ttaaaaccgc acctgtaaca tatttcagaa atactgtcac
    43921 ttgtatcggt caaacggcat accgcctcag ctacccggat ctcgttcaag ttatcgataa
    43981 atgtctttcc cgtccacttc ttcaagaaac gcatcaatga ggcatcgctc atatttgtta
    44041 acttagccac ttccgacaag gtgatacgtt tttgataatt ttcgtgtaaa tataacatga
    44101 tactatctaa acgatcggta tcgttattat tatagttctt taccgtgttc acggcattca
    44161 accgacgggc tgctttatcc aaagatagaa tcttaagaat ctcgaccaaa cgcaacaggt
    44221 tcttgaaaga atccggcttg ttatcgttcg acaacattct taatttatct tgaatgccaa
    44281 gtatcatttc ccggctgaaa acaagaccac tggaagcgtt atcaaacata tccttcatgg
    44341 tcttgaaatg ccgtctattg attaagctat caaataacga tttatgaaat tgtatcgtta
    44401 tctcaaagat cccattacac ggacacttat ggttcgagta agcatgcttc gttcctcccg
    44461 cgatcaacac caaatccaga tcatcgattt cctcgaccga atcgccaact atccgaatag
    44521 cgccagcggc attctccaga tagttcaact caaactccat gtgtacatgt aacggaaaat
    44581 taaaccccga tttcgggcgt tgcatgacca agaagcaatc ttctgatgaa agcggggtag
    44641 tttccttcaa tacgtctact ttccccatac acacaaagct tttttattcg agtatcaacg
    44701 tactgattac cgggcaatgg tcggatggga acaggttatt caacgtttca gtcaatacac
    44761 catgacgcaa taccttgata ttccctttca cgaagatata atcaatccat tcacgcttgt
    44821 cgtaagggat ctttccaaaa tcatggaatg tccattccgg gccgtaaata aaccctgcga
    44881 tcgtgcggga atgagtcaaa tgacgaggat cactcggatt agtcaatact tgtatcggct
    44941 catcagaagg cacggcattg aaatcgccag tcacgattat aggcaaattc tcggataatt
    45001 tcttcgcttg ctccagcacc aatgaagctc cttcatgacg agccactttc cccatatgat
    45061 ccaagtgcgt attcaagaag aagaatttct ttcccgtatt cttatctttc aagatcgccc
    45121 aagtagctac gcgctcgcat gcggcgtccc aacctttctt accaatggca tttatatctt
    45181 cggctaacca gaaattaccg cttttatcaa cggagaaacg atccttacga tagaaaatcg
    45241 gagcgtactc ccctttcgtc ttgccatcct cacgaccaac acccacataa gcgtattccg
    45301 gtaaacgatt aagcaaatca ttcagttgat tattcaagac ctcttgcgca ccgaacacat
    45361 ccgcctcata gaatttcact aaatcagcag cgaaatctct tctgaatttc cattgattat
    45421 ccttatcacc cgaattatcg taacggatgt tataagacat tacattcatt ttctcatcgt
    45481 tgtttttagc gaataagcaa ccagtggcaa ataaagccac cattaaacaa agtaaaattc
    45541 tcttcatgat attgattatt atatgtttct tatatgtctc agtatttatc tatggtcttt
    45601 gttacctcgc aaaaataaag tttatccatt tattaagcaa ataaggaaga acaaaaaagg
    45661 ccgacagatt gctctgccgg cctttcttta tagtttatta aacgttccta ttcttcatca
    45721 tctttgtcca tggcattgaa atcaaccacg ttcttgcgat tagcgaagat acgatcgaac
    45781 tcatcctttg cgcctacgat cagcttatca aactcacgct gaccggtacc ggcaggaatc
    45841 aagtgaccac agataacgtt ctctttcaaa ccttccaaac gatctacctt cccgttgata
    45901 gcagcctcgt tcaatacttt cgtcgtctct tggaaagatg cggcggacat aaagctgttc
    45961 gtctgcaaag cggcacgtgt gataccttga aggatctggt tggctgtagc cggaatagcg
    46021 tcacgtacct cgaccaactt aagatcacgg cgtttcaaca tactattctc atctctcaac
    46081 ttacgtgcag tcacgatctg tccggcctgc aatgtctgag aatctcccgg atcggtaaca
    46141 actttcttgc cccagatacg atcgttctcg tccattacct ccaacttatc aacaatctgc
    46201 tgctccaaga agcgagtatc tcccggatca accacctcta ccttacgcat catctgacga
    46261 acgataacct cgaagtgctt atcgttgatc ttcacaccct gtagacggta tacatcctga
    46321 acctcattca cgatatattc ctgtacagcc gtcggacctt tgatcgccaa gatatccgaa
    46381 ggagtggtag caccgtctga tagcggcata cccgcacgga tatagtcgtt ctcctgaacc
    46441 aataattgtt tagacagagg aaccatatat ttcttaacct cacccaactt agacgttacg
    46501 gtgatctcgc ggttaccacg tttgatctta ccgaatccta cctctccgtc gatctcagat
    46561 acgacagcag ggttagacgg gttacgagcc tcgaacaact cggttacacg aggaagacca
    46621 ccggtgatat caccggcctt acctacggca cgagggatct taaccaaaac ctcaccagct
    46681 ttcactacat caccattgtc tttcacgacg tgagcgccca acggcaaaga gtagttcttc
    46741 aagtaattac cattctcatc cacgatatga gcggccggag ccttcgtctt atccttagac
    46801 tcgatgatga tcttctcctt caaaccggta gtctcatcac tctcaacctt gtaagtcacg
    46861 ttctctacca aactctcgaa ctcgatctta ccggaaacct ctgacacgat tacggcattg
    46921 aacgggtccc actcgatgat cacgtcaccc ttcttaattg agtcaccgtt gttgaagaac
    46981 aacttagaac cataaggtat attatgagtc aacaacacaa tcttcgtgtt cggatcaaca
    47041 atgcgcattt cagccaaacg gcttactact accaaatgtt tctttccgct cacctcgtct
    47101 accgcctcaa cagcacgaag ctcgtcgatc tctaaaatac catcatattt agatgtaata
    47161 ctattctctg tagcgatgtt ggatgcgata ccaccgacgt ggaatgtacg caacgtcaac
    47221 tgtgtacccg gctcaccgat agactgtgcg gcgattacac cgacaacctc acccttctga
    47281 accatgcggt tcgtagccaa gttacgtcca tagcacttag cgcagacacc cttcttagac
    47341 tcacaagtca atacggaacg aatctcgacg ctctcgatcg gagagtcttg gattgcctta
    47401 gcggcatcct cacggatttc ctcaccggaa cgaacgataa cctcgcccgt aatcggatgg
    47461 atcacatcgt gaacagatac acgacctaag attctctcat acaaggaagc gatcacctcc
    47521 tcgttattct tcaattccgt acaaaccaag ccacgcaatg taccacagtc ttcctcgttt
    47581 acgatcacgt cgtgagagac gtcaaccaaa cgacgagtca agtagccggc gtcggcagtc
    47641 ttcaaagcgg tatcggccaa acctttacga gcaccgtgag tagagataaa gtactccaac
    47701 acggacaaac cttccttaaa gttagaaagg atcgggttct cgataatctg accaccttct
    47761 gcaccactct tctgcggttt cgccatcaaa ccacgcatac cggacaactg acgaatctgc
    47821 tccttagaac cacgggcacc ggaatccatc atcatataga ttgagttgaa tccatcgtta
    47881 tccgccgtca attgcttaat caagatatta gacaagttac tattaacgtg tgtccaagta
    47941 tcgataatct ggttataacg ctcgttgttg gtaatgaaac ccatattata gttagccatg
    48001 atctgctcaa cctcatcgta tcccttctga accaactcat ccttttcagg cgggatcaga
    48061 acgtccgcta agttgaagga caaaccaccc ttgaatgcca tatagtaacc caagttcttg
    48121 atatcgtcca agaactgagc ggtacgagcc acaccacaag ccttgattac ccgaccgatg
    48181 atgtcacgaa gagacttctt gcccaacacc tcgtttacat aaccaatctc tttcggaaca
    48241 aactcattta ccatcaaacg acctacagaa gtctctacca tcgtcttcac caagttaccg
    48301 ttcgcatcca aatcctccac gtaaacatgg atcggagcat ggatatccaa cttcttctca
    48361 ttgtaagcga tcgtagcctc ttccggacca tagaaagtca aaccttcgcc ttgtgtaccc
    48421 ttgcgcaact tggtaatata atacaaacca agcaccatat cctgagaagg tacggtaata
    48481 ggagcaccat tcgcagggtt caagatattg tgtgaagcca acatcaacat ttgagcttcc
    48541 aaaacagcct cattacctaa cggcaagtga acagccatct ggtcaccgtc gaagtcggcg
    48601 ttgaatgccg tacatgccaa cgggtgcaac tggatagcct taccctcgat caatttcggc
    48661 tggaacgctt ggatacccaa acggtgcaat gtcggggcac ggttcaataa taccgggtga
    48721 cctttcatta cgtactccaa aatatcccaa acaaccggtt ccttacggtc aacgatcttc
    48781 ttggcagatt tcaccgtctt cacgataccg cgttcgatca atttacggat aacgaaaggc
    48841 ttataaagct cggcagccat attcttcggc aaaccgcact cgtgcatctt taattccgga
    48901 cctacgacaa taaccgaacg agcggagtag tcaacacgct tacccaacaa gttctgacgg
    48961 aaacgacctt gtttaccttt caaactgtcg gacaaggact tcaacggacg attggcgtct
    49021 gtcttaacag cgctcgattt acgagagttg tcaaacaaag agtccacggc ctcctgaagc
    49081 atacgtttct cattacgtaa gatcacttcc ggagccttaa tatcgatcaa tcgtttcaaa
    49141 cggttattac ggataataac acgacgatat aaatcattca agtcagaagt agcgaaacgg
    49201 ccaccgtcca acggaaccaa cggacgcagt tcgggaggga tcaccgggat caccttcatg
    49261 atcatccatt ccggtttgtt acgacctctg gacgcacgaa aagactcaac cacctgaagg
    49321 cgtttcaagg cctcgttctt tctctgttga gatgtgtccg tgttcgcacg gtgacgcaac
    49381 tcataagaaa gagaatccaa gtccaagcga gccaacagat cataaacagc ctcagcgccg
    49441 atcttagcga tgaacttatt cggatccgta tcctctagca attgattttc tcttggaagg
    49501 ctatccaaaa tatccagata ttcctcctca gataataggt ctaactcacc gaccgtgtct
    49561 acgcaacccg gctggatcac gacgtagcgt tcgtaataga tgatggaatc cagtttcttg
    49621 gtaggaagac ctagcaagta accgatttta ttaggcaaag aacggaaata ccaaatatgg
    49681 gcaacaggaa ccaccaaatg gatgtgtccc atacgttcac gacgaacttt cttttccgta
    49741 acttccactc cacaacgatc gcagacaata cctttgtaac ggatacgctt gtacttaccg
    49801 caatggcact catagtcctt gatcggacca aagatacgct cacagaacaa accgtcacgc
    49861 tcaggcttat acgtacgata gttaattgtt tccggtttca aaacctcacc gctggagttc
    49921 tctaggatct cctcagggga tgccagaccg atggttattt ttgaaaagtt actctttatc
    49981 ttgttttctt ttctaaaggc catattattt atttataaag agttatcaat agataaagta
    50041 gacgggccgt agcccaccta cttctttatt gttattgaat taatccagag tgaaactcaa
    50101 accaagtcct ctcaactcgt gcaataatac attcagagat tcagggatac ccggctgtgg
    50161 catcggatca cccttcacga tcgcctcata agccttggaa cgtcctacaa cgtcatcaga
    50221 cttaatcgta agaatttcct gaagaacatg agcggcaccg aaggcttcca gtgcccaaac
    50281 ctccatctct ccgaaacgtt gaccaccgaa ctgtgcctta ccacctaacg gctgttgcgt
    50341 aatcaaagag tacggaccga ttgaacgggc atgcatctta tcgtcaacca tgtggcccaa
    50401 cttcaagaag taagtcacac ccaccgtagc aggttggtcg aaacgctcac cagtaccacc
    50461 atcatacaag taagacttac cgtagcgagg aataccagcc ttgtctgtcc attcattcaa
    50521 atcatccaaa gtcgcgccat cgaagatcgg agtagcgaac ttaacgtcca actcacgtcc
    50581 ggcccaaccc aacacggcct cgaaaatctg tcccaagttc atacgagaag gcacacccag
    50641 cgggttcaag cagatatcca ccggagtacc gtcttccaag aacggcatat cctcctgacg
    50701 aacgatcttt gatacgatac ccttgttacc gtggcgaccg gccatcttat cacctacctg
    50761 aatcttacgt ttcttggcga tataaacctt agccatctgt acgatacctg tcggcagctc
    50821 atcaccgatc gtcaagtcga acttcttacg tctcaactca gcgtcaagct ccttgtactt
    50881 cttcaaataa ttcaagataa cctgtttgat caactcattc ttctgagcgt ctgccgtcca
    50941 cttgcttact tggatggagt tataatccaa ttcttccaga gatttgcggg taaacttagc
    51001 acccttagcg ataatctccg tattcatata gtctttaaca ccttgagaaa ccttgccgtt
    51061 tgtaagcact aacaacttat caactaacaa agtcttcaag ctagccatct tttcttcgta
    51121 ttcctcgtcc aacttcggca agatcgcctt atcagtcaat ctggatttac gtttcttgac
    51181 agccttcgag aacaaagcgg tctcgataac cacaccgcgc aaagacggag tagccttcaa
    51241 ggaagcatcc ttcacatcac ccgccttatc accgaagata gcacgcaaca acttttcctc
    51301 cggagatgga tcagactcac ctttcggagt gatcttacca atcaagatat cacccggctc
    51361 gatgcgagca cctacacgaa cgatacctct ctcatccaaa tccttggtag cctcttcgct
    51421 gacgttaggg atatcggaag tcaattcctc cataccacgc tttgtctcac gtacctcaag
    51481 gatgtattcg tcaacgtgga cagacgtaaa gaagtcctca cgaaccatac gctcgttcaa
    51541 cacgatagca tcctcatagt tataaccctt ccaaggcatg taagccacct tcacgttacg
    51601 tcccaaagca agctcgcctt tctgggttga gtaaccctcg gtaaggatat cgccggcttt
    51661 cacacgttgt ccgcgatgac aggtcggttt caaatcgact gtcgtacttt ggttggtctt
    51721 acgccatttc gggatattat atgtcttaac cgcatcctcg aagctaacga attcctcgtc
    51781 ctccgtgcgg tcatatttaa tcttgataca agtagcatca acgaacacaa cctcgccctc
    51841 acgctcagcc ataatctgag tacgagagtc acgagcaacc tgcgcctcga taccggtacc
    51901 aacgatcgga gcgtccgtac gcaacaaagg aaccgcctga cgcatcatgt tagatcccat
    51961 caacgcacgg ttagcgtcat catgttccaa gaacgggatc agtgaagccg cgatagaagc
    52021 tatctgctgc ggagccacgt ccatcaagtc aatctcagaa ggagggacaa cagggaagtc
    52081 agcctcgaaa cgagccttca ccttatcgcg gataaactta ccgttatcat ccaatggagc
    52141 gttaccttga gcgattgtca actcttcctc ttcctccgcc gtgtagtatt gcaagccttc
    52201 ctcagagaag tcgacctttc catctgccac cttacggtac ggagtcgaga tgaaaccaag
    52261 atcgttgatc ttagcgtata cacataaaga agagatcaaa ccaatgttcg gaccttccgg
    52321 ggtctcaatc ggacaaagac gaccatagtg cgtatagtga acgtcacgaa cctcgaatcc
    52381 ggcacgctct ctagacaaac ctcccggacc tagggctgat aaacgacgct tgtgcgtgat
    52441 ctccgccaac gggttcgtct ggtccatgaa ctgagacaag gcattcgttc cgaagaaaga
    52501 gttaaccacg gaagaaatcg tcttcgcgtt gatcaaatca atcggagtaa acacctcatt
    52561 atcgcgaacg ttcatacgtt cacgaactgt acgtgacata cgagccaaac caataccgaa
    52621 ctggttatac aattgctcgc caaccgtacg tacacgacgg ttgcttaagt ggtcgatatc
    52681 atccacgata gccttcgagt tgatcaactc gatcaggtac ttgatgatct cgataatatc
    52741 ttctttagtc aagaccttaa catcagcgct tgtagtaagg cctaacttct tgttgatcct
    52801 gtaacgtccc acctcaccca gatcataacg tttctctgag aagaacaggt tcgtgataac
    52861 ctcgcgtgcg ctagcctcat cagccggttc cgcatttctc aactgtctgt agatatacaa
    52921 cacagcttcc ttctcggagt tactcgggtc tttctggagc gtattatata tgatagcata
    52981 gtcggacaga ttctggtcct cacgatgcaa caaaatattt tgcgtgcctg aatccaagat
    53041 agcctcgata ttgtcactat ccaatacaga ctcacggtcg atgattacat cgttacgttc
    53101 aatagaaacc acctcaccgg tatcctcatc tacgaaatcc tccacccaag tcttcaaaac
    53161 acgagcggcc agcttacgtc cgataaactt cttcaggttt gctttcgtta ccttcacctc
    53221 ttccgcaagg ttgaagattt caagaatatc tctatcgctt tcaaaaccaa tagctctcaa
    53281 aagagtagtt acaggcaatt tctttttacg gtcgatgtaa gcgtacatca cattgttgat
    53341 gtccgtagcg aactcgatcc atgacccctt gaacgggata atacgtgcgg agtacaactt
    53401 cgttccgttt gcgtgcgtgc tttgtccgaa gaatacgccc ggagaacggt gcagctgaga
    53461 cacgacaaca cgctcggcgc cgttgatcac gaaagtacct ctgtccgtca tatacgggat
    53521 cggacccaag tatacatctt ggatcaccgt atcgaagtcc tcatgatccg ggtccgtaca
    53581 gtacagtttt aacttcgctt ttaaaggcac gctataggtt aacccgcgag cgatacactc
    53641 atcgatacag taacgaggcg gatctatata gtaatctaag aactccaaca caaaattgtt
    53701 acgggtatcc gcaatcggga aattctcggc aaatacctta tacaatccct ccttctttct
    53761 cttttcagga ggagtgtcaa gttgaagaaa gtcttggaac gacttcaatt gaacttcgag
    53821 aaagtccgga tacgggaact gattctttat cgaagcaaaa ttaactcttt ggttttcagc
    53881 tgttgaagac atctagtaag gaatttattg aacttattga aattatagac acaaaaaggt
    53941 taagagtctt cgtagtcgga gactcttaac caaatcacct ggaaaccagg ttataaatac
    54001 tatttaagct caacttcagc tccagcctct tccaactgtt tcttcaatgc ctcagcatca
    54061 gctttagcga taccttcctt aattgcacta ggagcgctat ctaccatatc cttagcctct
    54121 ttcaagccaa gacctgttaa ttctttaact aacttaacga tagctaattt attagcacca
    54181 gctgctttca atacaacatc gaaagaagtc ttctcttctg cagcggcagc agcaccacca
    54241 gcagcaggac cagcaacagc aacagctgca gcagcaggtt cgataccgta ctcttcttta
    54301 aggatagtag ctaattcgct aacttcttta acggtcaagt ttactaattg ttctgcaaaa
    54361 gctttcaaat ctgccatttt tgtatgattt aaatgattat ttatctgtgt aatgttttaa
    54421 tgaaaaatta tctttcttcc aaagtcttca acagaccatg gatagtttgt cctgatgact
    54481 gaagagcaga gataacgttc ttcgccggag attccaacaa tgcgataaca tcggcaataa
    54541 gttcgttttt gctcttgata tttactaatg cctcaagatt ctcagcacct acatagaagc
    54601 tttcttgtac gtaagcagcc ttcaaagccg gtttagcgac tacacctttt ttagcgtcct
    54661 tagtaaaatc cttaatcagg cgagcgggag cattagcgac ttgtgagaac atcacagccg
    54721 tattgccttt caaagctacg ttaagatcag agaagtcacc ttcaatgttc tccaacgctt
    54781 tcttaagcaa gttattcttt acaacgacta acttaacctc acgcttgaaa cactctcttc
    54841 tcaatttgct ggttttctca gcatccaacg cctcgatatc cgtcaaatag aaattaggat
    54901 attcctttaa tgtttcagtt aattgaccta taacagttcc tttatcttcc tttctcattg
    54961 ttcaattgtt ttttagtttt cttcaactga tttggggtca attttaatac ccgcactcat
    55021 agtactagaa agataaatac tctttatata cgcaccttta gccgcagtag gtttcaactt
    55081 gatcaaagtt gaaataaact ccttagcatt gtcacgaatc tgttccggag tgaaagacac
    55141 cttaccaaca gatgtgtgaa cgataccgct cttatctacc ttaaagtcga tcttaccttg
    55201 cttaacctcc ttcaccgcat ttccgatctc attggtaacc gtaccactct ttgggttagg
    55261 catcaaacca cgagggccta atacgcgacc aagagcaccg atcttaccca tgatagaagg
    55321 catagtgatg ataacatcaa tgtcagtcca accgccttta atcttattaa tatactcatc
    55381 caatccaaca tagtcagctc cagcggcagt agcttcagct tccttgtccg gagtacataa
    55441 tgcgagaacc ctaacctgct taccagttcc gtgaggcaat gaaaccacgc ctctcaccat
    55501 ttgattggcc ttacgggggt caacacctaa acggacatca acatctacgg atgcgtcaaa
    55561 cttagttgta gtaatttcct tcactaaagc tgaagcttct ttcaatgtat atgctttccc
    55621 agcttcaatc ttgcccaaag ccaacttttg attctttgta agtttactca tctcaattga
    55681 agtttattaa ttattacccg ggaatgtccc tttaacagtg atacccatac ttctggctgt
    55741 tcccgcaacc attctcatgg ctgactcgac agtaaagcag tttagatcga ctaatttgtc
    55801 ttcagcgata gctttcacct gctcccatgt gatctcagcg atcttagcac ggttaggttg
    55861 agcggaaccg ctcttcttct tagtagcttc caacaactgg attgccacag gaggagtttt
    55921 aacgacaaag tcgaaagact tatcggcata gtaagtaatt acaacaggta atatcttacc
    55981 agccttgtct tgggtcttgg cattaaattg cttgcaaaac tccataatgt taataccctt
    56041 agaacccaaa gcaggtccta ctgggggaga agggtttgct gctcctcctt taatctgcaa
    56101 tttgatttgt ccagcaactt ctttagccat tgtttctaaa attttttaga tatataacat
    56161 caataacaga aaggtagcac ttttcgtaac cagagtacta ttctttctca acttgcatat
    56221 aacccaactc aaggggagtc ttgcgtccga agaccttaac catcacctta agtttctttt
    56281 tctcggcgtt gacctcttcg attatacccg tgaaaccgct gaacggtcca aaagtaatct
    56341 tcacactctc gccaacatag aactggatat ccagatcctc ttgttgttcc tgcaactcgt
    56401 caaccgtacc taagatacga ttcacttccg caggacgtaa tggcacgggg gtatcagaac
    56461 cacccaagaa accaatcacg ttcggaatgt tccgcaatcg atgagcaacc tcaccgacca
    56521 aagcggcctc aaccagtaca taacccggca agtaagccct ttctttcatg accttcttac
    56581 cgtttcgtac cgtaaaggtt ttctcggtcg gaatcaagac ttgagataca tattctccca
    56641 gatccgtatt cttcagctca gcctctagat attcccgtac cttgttctcc ttgccactga
    56701 tggcacgcag aacataaaat ttcttttgga tatcagacat accttaactg attagaaaat
    56761 ttggttgtag aagaaacgca taacagcctc gaaggccccg tcaacaacaa agatcaatgc
    56821 ggcgatgata agggaagcaa acataacaac aaccgcacta ttggaaagct ctgctctcgt
    56881 aggccaagaa actttataaa caagttcgtt ataagattcc ttaatataag taattatctt
    56941 tttcatcgaa tctatagatt ttagcacgga aggagaggct cgaactcccg acacctggtt
    57001 ttggagacca gtgctctacc aactgagcta cttccgtaga aatagccagc ccttaaaaag
    57061 actggctata acattatcta atgcttgaat tagttctcta attctgtgat ctggcctgca
    57121 cctactgtac gtccaccctc gcggatagcg aaacgaagac ctacgctaca tgctaccgga
    57181 tagatcaact caacctcgat cgttacgtta tcacccggca ttaccatttc agttccttcc
    57241 ggcaaagtga tctcaccagt tacatccaat gtacggatgt agaactgagg acgatatttg
    57301 ttgtggaacg gagtgtgacg accaccttcc tctttcttca agatataaac ctcagccttg
    57361 aacttagaat gctctttaac ctgacccggg tggcagatta ccataccacg cttgatctca
    57421 ttcttatcga taccgcgaag caacaaacca acgttgtcac cagcctcacc ttgatccaat
    57481 aacttacgga acatctcaac acctgtaaca acagatttct taccagcagc gccaagaccg
    57541 atgatttgaa cttcctcacc taccttaacg atacctgtct cgatacgacc tgtagcaaca
    57601 gtaccacgac ctgtaattga gaatacgtcc tcaaccggca tcaagaacgg cttgtcgatt
    57661 tcgcgcggag gcagaggaat ccaagtatca caagcttcca tcaactccat tactttatct
    57721 tcccattgag catcaccgtt caatgcacca agagcagaac cacggatgat cggagtgttg
    57781 tcaccgtcga attgatagaa tgaaagcaac tctctcatct ccatctcaac caattccaac
    57841 atttcctcgt cgtcaaccat gtcacacttg ttcatgaata caaccaatct cggaacgttt
    57901 acctgacgag ccaaaaggat gtgctcgcga gtttgaggca taggaccatc agtagcagca
    57961 actacgatga tagcaccgtc catctgagca gcaccagtta ccatgttctt tacgtagtcg
    58021 gcgtgacccg gacagtctac gtgagcatag tgacggtttg cagtctgata ctctacgtga
    58081 gaagtgttga ttgtgatacc tctctctttt tcttcaggag cattgtcgat agaatcgaat
    58141 gaacgcaact ctgaaagacc tttctttgcc aatactgttg tgatagcagc tgtcaaagtt
    58201 gttttaccgt ggtcaacgtg accaatcgta ccaatgttca catgtggttt cgatctgtca
    58261 aatttctctt ttgccataac ttaattgttc tttatttgat taatgatcat gttcaatttt
    58321 caattgagcc ggtgccgaga cttgaactcg ggacctcttc cttaccaagg aagtgctcta
    58381 ccgctgagct acacaggcaa cttataagag cggaagacgg ggctcaaacc cgcgaccctc
    58441 agcttggaag gctaatgctc tatcaactga gctacttccg caagaccaaa tgaaccaacc
    58501 gattctctcc tttgtttcat tcgtgtgggc agtgatggat tcgaaccacc gaaggcgaaa
    58561 gccagctgag ttacagtcag ccccatttgg ccactctggt aactgcccat tccaatacat
    58621 tcttttgagc ctcttgtcgg attcgaacca acgaccccga gattacaaat cacgtgctct
    58681 ggccaactga gctaaagagg cgatacttct aaaagcagcc gtttcgtcac cacggcgaaa
    58741 cggctgcaaa tttagatatt atttcttaca taccaaattt atctaccgtt ttttttattt
    58801 ggctctgatt ttttctttga atttaaccag ttgcttctcc aaagcctcaa cacaatcgtc
    58861 tatcgcccct tcgaaagtat cgtttatttt atcagcgaaa cattccccgt tcttcacgga
    58921 caacattata ctggcctgct tgttcttcac cgtctcaggc ttaaccacct tcaatgtaac
    58981 ctctgccaat ataataccat cgaagtattg ctccaattta gaaactttct tctgaataaa
    59041 cgcctccaac tgtgcagttg cgtcgaaatg aattgcttga attctaacgt ccataataac
    59101 ctccttcttt ttttgctctt ggatgagcat gatacacttt ttttaattcc tcaaaggttg
    59161 tatgcgtgta aacactggta gacgctaaac tgctatgacc taataaatct ttcacagcgt
    59221 tcagctcggc tccgttgttt aacatactcg ttgcaaatga atgtcgtaac acgtgtggac
    59281 ttcgtttcgc cagcatgggt atctccgaca attgcttttt tactatatta taaacaatcc
    59341 ccgtcgacaa ctggttccca ttctttcgaa cgaaaaacca ttcaccggct gcttcaacct
    59401 cacgatcacg gacttccgtg tatgcaagca ttaagttttt taaaccctcc gcaaaaggaa
    59461 tcaaccgctg cttgttccgc tttccggtaa ccttgacctg catcgcctca taatccacat
    59521 ccacgtttcg tatgccgatt aactcagagc ggcgcatccc ggtatcgtat agcatctcaa
    59581 tgaccaaccg attcctcaca ccttcaaaat cctcatcaaa tccgtccccg tccaacaacg
    59641 cctccaactc gctatcctta ataaaataag gtaagggttt cttcgttttc ggaccgctca
    59701 ccaatctcaa cggattcgcg gagacaatcc cccgtttcat gagaaactta aaaaaagatt
    59761 tcaaagaact taatttccgg tttaccgata cgggagaaag cttctcgtcc atcaaactga
    59821 cgatccagct tctcacgaaa tccgagtcga tttccccggg gtcgaataca ccttctcgat
    59881 gctctcttac atacctctgg aattggtcca aatctttcga ataggcacca atcgtataat
    59941 tggaatagtt ccgctcatac cggagatagt ttagaaagtc atcgatcagc atattctcgt
    60001 tgcatcaaca ttcatacaac gaaaatagga ataagaattc aataaaacaa gcccggaagc
    60061 tataattatt cttctacttg ttgcaaatgc tgtacgtaga tagcacgcat agtctgcttt
    60121 ctcttcgtaa cagacggttt ctcgaaagcc tgacggcctc ttaattcctt gactacacct
    60181 gttttctcga actttctctt gaatttctta agcgccttct cgatgttttc gccttctttt
    60241 aatggaacta cgatcataat ttaaattgtt atattgttta attatttata tcctcaaatt
    60301 gagcggcaaa attactgatt gtttcgggat tagcaaaact ttcagcgatt atttttacaa
    60361 aagatgcctt tctccgtaat tatagccgtg attagctcgt ggggagtaat gtcgaaggcg
    60421 gggttgtaga cttttacgtc tttcggggcc atacgccttg aataccacat ctcggtgacc
    60481 tcatcggggt tacgttcctc tattacaatg gaatcgccgt ccgggcacga gccatcgatg
    60541 gtggatgtcg ggcctaatac atagaagggg atcttgtaat gccgggccaa gatagccact
    60601 ccggacgtgc cgatcttatt cgccacgtcg ccattggcgg ctacacggtc gcaacctacg
    60661 accacggcat gcacccagcc tttccgcatg acgatagagg ccatattatc gcaaatcagc
    60721 gtcacgtcca cgccggccct gcttagctca taggccgtga gccgggcgcc ttgcaacaaa
    60781 ggacgggtct cgtcggcgaa gaccttgaaa ccataacctc tctcctgccc cagataaatc
    60841 ggcgccaagg cggtgccata ctccgagacc gccagatgtc cggcgttgca atgcgtaagg
    60901 attcccatcc cgggacggag tagctccaga cagttctcgc cgatctgccg gcaagcggcg
    60961 gcgtcttcct cccggatcgc gatcgcttcc ttatataata gctctttcca ttccgggaca
    61021 gacaaggttg gatgagcgac caatacccgc tccatccggt tcagcgccgc caccagattc
    61081 accgctgtcg gacgggaacc ggccagatac tccttgatct tccgaaactc attcacgaaa
    61141 acggatttct ccgccgtatc gatccgacgg gcgcagacat agataccata agcggccgct
    61201 accccgatag caggtgctcc acgtaccttt aatttataga tggcatccca tatctcctcg
    61261 gcagtggtaa gggtcagata cgcctcctta cccggcagca gagtttggtc caaaatgatc
    61321 acaccgtccg cttgctcgtt gaaacgcaca gtctttaaat cagatagagt ttgtatcatt
    61381 cgatatgaat atattaatag ttcacgggac ccagcgtagc ttctatcgcc acccctgcgg
    61441 cggtaaccgc tatcgctcct acgacaaggc ctgccgtagc tccatgagtc tctttcacgt
    61501 aaaagaaatc gccggattgc tgctgtccct catcgaaata ctggggagcc acgtcgccga
    61561 ccttgatcaa tttcgccaga tagaagttcc gctcaaaaga ggaatgcttc aagggcttcc
    61621 cattggtccc tccggcgaac aacgtcaggt agctacggaa tctcagcgga gaatcttcct
    61681 ccgtaaaatc ctttacacgg atatttacgg tggtgtttgc tttcgttgtc atttgctcct
    61741 ttacatactc ttccttcggg atctcgttaa acgggaagtt ggctaattgc aaaggcgtat
    61801 tgactaattt ggaatgcgga gggataaact caacgccctt cggcaaactc acatcaccgg
    61861 agaaggaacc ttccgagtag ctccacccgc tgctgctcct atcgctccaa tgaaaggagc
    61921 taccggatgc cacgctagag ctctcgcctc tcaccgaggc cactttcgga tcgtaggtgg
    61981 tagccacgtc atcgataatc agcgccgacc gcccccaatc cacatacaag ggttcatcca
    62041 gtttattata aatggtaata gtaaccgggg cgttctctcc ccagaaacga taagagatac
    62101 gtaccgtatc gttttcctgc acaaaatcac ctctctcatt cttctccccg acggggtcat
    62161 tcgagttcaa catcgaataa taataagaag aacatgcgct caagccgaga agcagagccg
    62221 caaagacaaa aagataaagc agattcctca tggcacttct tatttgtttc tacaaagcta
    62281 gcaaattatt ccttgatatc tattgggtgc cttatcttta acttgattta aagggatcgg
    62341 ttcacaaggt tgtggaccac aaggctgtga gcccatacac gtttatcata acctttagct
    62401 cttttatctg aaatcctaac ccttttctcc tttatatgtt gtacctttga agctgaagta
    62461 ttcattatcc accatctgtt agacgatcat ctaacgaatg gtggatgatc ttccaacagt
    62521 tggtgcatga tcatgcaacg gctgttggaa gatgaatcct tcttgaagaa accgctaagc
    62581 tcgcctatag aaacgggtaa gcgatccaga agaatcagac aaaagatcta taaccattta
    62641 aacacagcac agatgtcagc aaattacaag ctagtcagaa atcccaaccc gaatccagag
    62701 gaatccggga agtcattacc cctacatcct cgtttggtct cttgcgggac gatacatacg
    62761 gatgagttca tcaatagagc gaagtcccgg tcttctttct cgcctgcgga tatgaaaggg
    62821 atcttgcagc ttttccaaga catgatggtg gacttcctca tgtacggcta taacgtggag
    62881 ctagagggga tcggtacttt cagcgtctca ctgaaaagcc ggcccgtgat ggaaaagaat
    62941 gagatccggg cggaatccat ccatttcaag gacgtgaagt tcagatcgtc caaggaacta
    63001 agagaccggc tgaagaccat gccggtgttt cgtgacgagt acacggttag cgatcccgca
    63061 tatccctccg ccaaggaatg cgagcaagag gtattccgtt atctggagac gaaccctttt
    63121 atccaccaga agaagtatat gtcgctctgc ggatgctcca gaagtaaggc ttccctcgac
    63181 ttgcggcggc tagtagagga agggaaactg cggtgggaaa agctaggtac ttcccatcta
    63241 tattataagg tagaagagcc ggtttccggc gagacaaatc caaaataatt cattaacttt
    63301 gcgagtatta atgttgacta aaataaaatg cgatgaaaac aaacattcct gaacgtatcg
    63361 ccgccctacg ggaggctatg agacaacaga aggttgacgc ttatatcata cccagttccg
    63421 acccgcatct aagcgagtat ccggccgatc gctggaaatc gagagaatgg atatccggct
    63481 tcaccggctc ggcgggaacg atcgtggtca ccgcggacaa ggcgggctta tggaccgatt
    63541 cccggtattt cctgcaagcg gccagccaac tggaaggttc cggtatcgaa ctctataagt
    63601 tggcgcttcc ggagacaccg tctatcacgg aattcctctt gcatgagtta cacgccggac
    63661 aggccgtagg actggacggg caaacctata gcgccgccga agcgagtgcc ttggcaaata
    63721 aactaagccg taaagaaatc aagctggata cctcggccga cctgatcgag ggtatctgga
    63781 aggaccgtcc cgccgttccc ggaaacccga tattcgagat gccggaagca ttaagcggag
    63841 cctccgtgca cgagaaacta gacctaatca ataaccagtt gcggagcgag ggcgccgact
    63901 gcttgatcct cgccgccttg gacgagatcg catggacatt caatatccgg ggtacggacg
    63961 tgacctataa cccagtcgta gtcagctacg ccttcgtatc ggaggatgag agcgtgcttt
    64021 tcatcaagcc ggagaagctg accgccgaga tcaccgagca tttgaagaaa gaaggggtta
    64081 cgctggccga atactccatg atccagaggt atctgtcccg cctaccggaa aacagccggg
    64141 tattcgtgga tatgaacaag acgaacgtct ccttatacga cgcgatcccg ggaaactgta
    64201 cgatcgtgga agggatctcc cccgccaacc acttgaagag catcaagaac gagaccgaga
    64261 tcaagggctt ccaaaacgcc gtggtaaaag atggtgtcgc cttgacaaaa ttctatatct
    64321 ggctggagaa acaaatggcg gaaggagccc aagttacaga gatcagcgcc gccgagaagc
    64381 tgacagcctt acgtgcggaa caaccgcaat acatcatgga tagcttcggc acgatctgcg
    64441 gctacgccga gcatggagcg atcgttcatt actccgctac gccggagacg gacgcgacct
    64501 tgaaaccgga gggattgctt ttaatcgatt ccggtgcgca atatctggac ggtacgacgg
    64561 atatcacccg cacgatcgcc cttggagagc cgacggagca gatgaaaaag gatttcaccc
    64621 gtgtattgaa aggtacgatc agcttggcga aaagcaagtt tcccgccgga acacgaggct
    64681 ctcagatcga tatccttgcc cgtaaggcgc tatgggattc cggcattaat tatttgcacg
    64741 gaaccggtca cggtatcggc cattgcctga acgtacacga aggcccccaa agcatccgca
    64801 tggaggagaa cccggtgacc ttgaagcccg gaatggtgat cagcgacgag ccggccatgt
    64861 atcgtaccgg cgaatacggt atccgtacgg agaacatgat cttggtacgt gaggacagcg
    64921 agacggaatt cgggaaattc ctaggattcg atacgctgac gctttgtttc atcgacacga
    64981 gcctgattat catccccatg ctctctgtcc gcgagcacgc ttggctgaac aagtaccatc
    65041 aaatggtcta cgacaagatc agcccgttct tggacgagga ggagaaagct tggctgaaag
    65101 agaaaacaac agaaatttaa acaactaaaa atggcattaa ttaaatccgt tcgtggcttt
    65161 accccgaaga tcggtaaaga cactttttta gcagacaacg ccacgattat aggtgacgta
    65221 gagatcggtg aaggttgcag tatctggttt ggcaccgtgc ttcgcggcga cgtgaactcg
    65281 attcgcatcg gcaacggcgt aaacgtacag gatggttccg tccttcacac cttatatgag
    65341 aaatcgacga tcgagatcgg cgatgatgta tccatcggcc ataacgtaac gatccacggg
    65401 gcgaagattt gcaatggcgc cttgatcgga atgggctccg tggtattgga tcacgccgta
    65461 gtaggcgagg gagcgatcat cgccgcaggt tccgtagtat taagcaagac gatcgtcgag
    65521 ccgggcagca tctacgccgg agttcccgct aagttcgtca agaaggtaga tcccgagcaa
    65581 gcgaaggaga tcaaccaaaa gatagccaag aactatcata tgtattcttc ttggtataaa
    65641 gaataatagc atgtatttga ttatttgaat tataaaccat atatttgtat ctnnnnnnnn
    65701 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    65761 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnttacccaa gatcgatcaa tatccgattt
    65821 tcgagaaccg ggtcgtaaaa gcaggttcgc cccgcccttg ggaactatcg gaagcttaca
    65881 atacgaaaag tattccagag cgttatcttc cccggtttga ggagctgggt acggttgcct
    65941 atgtaatcat ccaagacaat cgattgctat tcgagcaata ttgggaagat tactcgccgg
    66001 aatcgcatag caactccttc tcgatggcga aaagcatcgt ctcgttagcg atcggctgcg
    66061 ctatcgacga tggatttatc cgcgatgtcg atcaaccggt aagcgacttt ttcccggaat
    66121 tcaagggata cgacggaaag gccctaacgc ttcgccattt gctgaccatg agcgccggcg
    66181 tggatttcga cgaggcttac aactctcctt tctctcctac cacccagttg tattatggcg
    66241 atgacctaca ggaaattgcc ttcgggatga aagagatcga cgagcccggc gtaaacttta
    66301 tctaccaaag cggcgtgaca caactgctgg gctttatcgt ggagaaggct accggcgaga
    66361 aactcagcga ttatgtatcc cgcaaactat ggactccgat gcacgccgag gaaagcgccc
    66421 tttggagcct cgaccggaag gacggcatgg aaaaagccta ttgctgtttc aacagtaacg
    66481 cccgtgattt cgcccgcttc ggacaattat tactcaacaa cggccaatgg gatgaccggc
    66541 aattgatctc tcccgcttat ttggcggaag cgacaagccc cgatacccgt cttgtctata
    66601 aggatctcgg caaacccaac cattgttacg gattccaata ctggattctc gattacaaag
    66661 ggatgaagat cccttatatg agaggaatct tggggcaata cgtcttcacg ctcccgaaaa
    66721 agaacgccgt gatcgtaaga ctcgggcaca aacgcagcga tacttatacc gccgaccaac
    66781 attatccgga cgatataaat acatggttgg acgcggcgat ggacttactt caataagaat
    66841 ctatttatca aacgatctaa aaataaacgc acatgagaaa aacgatttta acgacagcgc
    66901 cattggcggc actcctattg ctttcttgcg cacagaaacc cagtacgcaa aagccggaca
    66961 tcacgtatat gccgcaacca ccgttcaatc cgccgacgta tgtttgctac aaggcccccg
    67021 ctcctatcaa gatcgacgga aagctttctc ccggggaatg ggacgcgata ccttggacca
    67081 gcgacttcgt agatatcgaa ggcgacaaac gcccggcccc tcacttccag acccgggcca
    67141 agatgactta cgatgataac ggaatgtact tcgccgtcct tatggaggag ccgcacgtat
    67201 gggcgaccat cacggaacac gacgccgtga tcttccatga caacgacttc gagatcttcc
    67261 tgaatcctac gaacgacacc cataattatc tggagtacga ggtgaacgcc ttgggtacgg
    67321 aatgggactt gttcttaacc cgcccctacc gggataatcc gcaagtattg aataactggg
    67381 agttcgccgg aatgaaatcc gctgtttatg tagacggtac gctgaataac ccgaaagaca
    67441 cggataaatc atggagcgta gaggtattca ttccttggac ttccgtattc caaatggaca
    67501 gaggaaaaga aaagccggaa atcggcgagc agatccgtgt gaacttctct cgtgtggaat
    67561 ggacaacgga cgtgaaagac ggtaaatacg tgaaagtccc tatccaagga gaggataaga
    67621 ttcgcgagta caactgggta tgggcgccta ccggggtaat caatatccat atgcccgaat
    67681 actggggtta tgttcaaata tcggataaga ttgcgggaga aggtgagact cctttcgtaa
    67741 aacatccttc ggaggagacg aaatggatct tgcgtaattt atattaccgt cagaatgagt
    67801 tcgccgcgac cttcggacat tatgccgata acatcaacga cttgaaggca aacgagctat
    67861 gcccgcaaga gatcgccaat caactggaaa tacatacgac accttccatg tatgagatat
    67921 cgctacccgc accagacggt acggtatgga atatccggca agacggtctg gtatggccta
    67981 aaaagaaata acacaattta ttaatcaact aaaatatcat gaagcaaaag aatttatgga
    68041 tagcggcctt ggctttaggc atcacgctat cggctcacgg acaacaaagc ggtggaggca
    68101 tctcacccac gatgttgcag caaatcaaac agtcttatca gggaacgccg gccgataagg
    68161 cgatccgtaa cgcgatcacc aataacgaca tcaacaagct tgccgttaat ggggagagca
    68221 agaacaattt ggatacttac ttctccaata aggtagagag caaagggatc tccaaccaac
    68281 gttcctcggg ccgttgctgg cttttcacgg gattgaacgt gttccgtgcg caggcgatcc
    68341 ataaatacga catgggtgaa ttccaattct cccagaatta ttctttcttc tgggatcaat
    68401 tggagaaagc gaaccttttc ttacagggca tcatcgatac tcgtctgaaa ccgatggacg
    68461 acaagatggt ggaatggtta ttcaagaacc cgatcggaga cggagggcag ttcacgggtg
    68521 tctccgatat cttgaccaag tatggtgtgg ttcccgccga ggtcatggta gagaccaaca
    68581 gtagcaacag taccggacgc atgagcaacc tgatcggatt aaagctgaaa gaatacggct
    68641 tgcaacttcg tgacctgtct acgaccaaag gcacgaccgt agcggatctg gagaaaaaga
    68701 aaacagagat gctaggtacg atttaccgta tgctcgtatt gaacttggga gagccgccta
    68761 cgaaattcac gtggactcgc aaagacgcta aagggaatcc ggtagagacg aaggaatata
    68821 cgcctcagtc cttcttccaa gaatatatcg gggacgattt gagaaacaac tatgtcatgt
    68881 tgatgaacga tccgagccgc gattattata agttgtatga gatcgattac gaccgccacg
    68941 cttacgatgg caagaactgg acttacgtaa accttccgat cgaggatatc aaacaaatgg
    69001 ctatcgcttc catcaaggac agtaccatga tgtatttctc ttgcgacgtg ggcaagttct
    69061 tcgatcgtga cagaggcatt ctggatgtaa acttctacga ttacggttca ctgatgggta
    69121 cgactttcgg catggataag aaacaacgta tccagacatt cgccagcggt tcctcacacg
    69181 ccatgacctt gatggctgtt gatctcgacg cgaatggaaa gccgaagaaa tggatggttg
    69241 agaatagttg gggtcccgga gcgaacgccg gccacctcat catgacagac caatggttta
    69301 atgagtatat gttccgtctg gtagtcaaca agaagtacat cacggatcaa gtaaaagaga
    69361 tcttgaaaca aacaccgact cgccttcccg cttgggaccc gatgttcgct gaagaggatt
    69421 aaaataaaac acggatgaga tagacaacgc gaatcgttca attaccaatc cgtacatcta
    69481 tctcatccgt attccattgc tatatcaaaa gagtctgggc atacaatcac tcgaatagca
    69541 aacccggctt tatctattaa cggatatgga tttgccgcaa gatttgatcc gtcgctccta
    69601 cactgttttt cacaaaatca ccggcagctt gcccggaggt ttccaaggct gtcgggtcgg
    69661 tcaataactc gtccatcttc gttcggaaag aggaatcgtc tgtgatggag aaaccaccac
    69721 ctacggcgat cagatccttc gcctccttaa acttatggta tctcgggccg aataagaccg
    69781 gcatcccata aacggcggct tccaacgtgt tgtggatacc cgctccgaaa ccaccaccga
    69841 tataagcgat ctgtccatag cgataaatgg aagataagag tccgaaactg tcgatgatca
    69901 agcaatcctt atcggccaga tcatcctcat gcgcctccga tagacggacg gacggacgtt
    69961 ttagcatcgc ctcgatagaa aggagatgtt cccggtgaat ctcatgcggg gcgataatca
    70021 acttcatctc cggatgctca tggaaataag ggataaagat cgcctcgtct tgaggccatg
    70081 aactgccggc caccatcacg atcggcctct taccttcctt gctttccaag aaacgttcga
    70141 taaacggaag ctcacgagct tgcttacgga catccaacac ccgatcaaaa cgggtatcgc
    70201 cggtcaccgt cacattcgtg ataccgaact cgttcaagag tttcatcgaa cgctcgtcct
    70261 gaacaaaaag atgattaaaa taagatagca tcttccggta cggttttccg aaccattgga
    70321 aaaatagctg gtcggggcgg aatatagcgg aaatgatata aaccggtatt ccccgcttcc
    70381 gcaactcacg caaatagttc ccccaaaact cgtacttgat aaatatggcg atcgccggat
    70441 tcgccagatt caggaacttc ttcacccgga aaggcgtatc aaaaggaagg tagcagatca
    70501 cgtccgctcc cttgtaattc ttccgtacct cataaccgga gggagaaaag aaagtcagca
    70561 acaccttata ctccggatgt tccgccttga tcttctcgat catagggcgc ccttgctcga
    70621 attcacccaa cgaggaggca tggaaccaga tgtatttagc gttccggtcg attttctcac
    70681 gaagtatgga atttgttttc cattgcccga atcgcatcag tctcgccttt ttatggaaag
    70741 gcgagatcaa agcgactaca aaagcgtaga gatgtattgc taaactgtac atgattattt
    70801 taatatctcg atagcccgtt ggatacggcg gatagactcc tctttaccta aagcctcggt
    70861 aatatcaaag atgccggggc ccttgccctc gccaaccaag gccagacggg cggcgttcat
    70921 gatattcccc aaatgatatc ccttgctctc gatccaagcc ttgcactcgt tctcggtacc
    70981 ttctacgtcg aacggctcac gggcacgcag ttgctcgata aactcaccca attgaacagc
    71041 cgaatcttcc ttccagcgtt tcttgcgagt cttctcatcg tactccgtcg gggcgataaa
    71101 gaagaaagag caaagatccc ataactcact cacgaaattg acacggcctt tcatcatgcc
    71161 gactactttc tctacataag catgggtagt ctggataccg tggctctcca cgatcggcaa
    71221 gaacaggtcg gcgatctccg cgttactctt ctccagtaaa tagtggtggt taaaccatct
    71281 gcctttctca taatcaaact tagcgccgct cttgctgcaa cgagacaggt cgaacaaacg
    71341 gatcaaatca tccatgctca tcacctcctg atcgttaccc gggttccaac ccaacaaagc
    71401 gaggaagttt acgacagcct cggggaagta gccactctca cgatagcccg atgagacatc
    71461 acccgtcttc ggatcgtgcc attccaaggg gaatacaggg aagcccagac gatcgccgtc
    71521 acgcttgctc aacttaccat taccttccgg tttcaacagc aacgacaggt gggcgaaact
    71581 aggcatcgta tcttcccaac cgaagaaacg atataataat acgtgaagcg gcgcgctcgg
    71641 caaccactcc tcaccacgga tcacatgggt aacctccatc aaatggtcgt caacgatatt
    71701 cgccaagtgg taagtaggca attggtcggc cgatttatat aataccttat catccaagat
    71761 agaggagttg ataacgacct cgccacggat caagtcgttc acgtggatat cctcattcgg
    71821 ctcgatcttg gcacgaacta cgtactgatg acctgactcg atcaggctct gaacctcttc
    71881 ctgagaaagc gtcaacgagt tgcgcatttg cgaacgggta gaggcgtcgt attggaaatt
    71941 ggcgatctcc ttccgtttct cctccaactc ggcaggcgta tcgaacgcta tataagcatg
    72001 gccatcgttc agcaattgat cgacatactt cttgtagatc tcacgacgct cgctctggcg
    72061 atacggaccg tagttgccgc cgaagctcac gccctcgtcg aacttgatac ccagccaagt
    72121 caaggcctcg atgatatagt cttccgcccc gggaacgaag cgttgggaat ccgtatcctc
    72181 gatacggaga atcatatcac cgccattctg tttagcgaat aaatagttgt ataaagccgt
    72241 gcggacacct ccgatatgca gcgcccccgt aggactaggt gcgaagcgta ctcttacttt
    72301 tctttgagtc ataatactta cattctataa taatgcggca aaagtacgcc tttttttccg
    72361 cttagtgaag ttttttacgt atatttcgga cgctaaaagg aatctatatg aaacagaaga
    72421 attacaatat accgaccgtg gtctacttcg tggtgaccgc gttacttatc gcctacttct
    72481 tcccccggga gggaaaattc cgttatcagt tctatgaggg caagccttgg agatatggat
    72541 tactcaccgc cccgagcgat ttcccgatct acaagaccga cgacgaggta aaagcggaga
    72601 aagacagcgt actccgtaag ttcgagcctt attaccgcat gaaccccgac atccagaagc
    72661 aagaggtcga gaaactgcgt gccaactaca ataacggcaa taacttgcga agcaaagtat
    72721 cccccgctta catgcagtat atagagagca gcctgatcaa cttatacaag aacggtatca
    72781 tctcgtcgca ggatctggac gagctacgga aagaggaata ctcccgtgtc aacctcttgg
    72841 agaacgccgt cgcgcagacc cgctacgtga gcgacttctt caccgtgcgc accgcctacg
    72901 agttcattat caacaactgc ccgccgcggc tggacaaatc gatcctgcaa tcgtgtgaca
    72961 tcaataacta cctcaccgag aacatatcct atgccgccga catgtccgac aagatcaagg
    73021 aggatatgct acagagcgta tctatcgcta acggtatggt acaagccgga gagcgtatcg
    73081 tagaccgggg cgagatcatc gacaaccata cctacaacgt gctccgttcc ctaaaggcca
    73141 tacacgaggc caagacgggg ggcacgcaga cgcaaggcat catactggcc gggcaattcg
    73201 tgctcgtctt cgggctgatg ttctgtttct ggctctacct atggtctttc cgcttgaaga
    73261 tattccataa ccggaagaac gtactattct tgatcctctg catattcgtg agctgcatct
    73321 ttacggaact atgtgttacc tacgcattat tcaacgtata tatattgccg ttcgccatcg
    73381 taccgatcgt ggtacgtacc ttcttcgatt cccggacggc gcttttcacg caccttatta
    73441 tcgtgctgat ctgctcgttg atggtacctt tcccgcatga gttcctgttg ttgcagatcg
    73501 tggcgggtat ggtagtgacg ttcagcttga aggagttgag cgaacgttcg caactgatcc
    73561 gttgcgccgt cttcatcttc ctctcctacg ccgcctgcta cctcagtctc acgttgtatc
    73621 aagaggcgaa cttaaacaag atcaactgga tgatgatgct ttatttcggt atcaacttca
    73681 tcctgctgat gttcacctac gtattggtat atatgttgga gaagacgttc ggatacgtgt
    73741 ccagcatcac gctagtggaa ctgtccaaca tcaacaaccc gatcttgaag aagcttagcg
    73801 agacttgccc gggcacgttc cagcactcct tgcaggtatc catcctcgct tccgaggcgg
    73861 ccgccaagat cggcgccaac gcccaactgg tacgtaccgg cgccctttat cacgacatcg
    73921 ggaagatgag caaccccgtc ttcttcaccg agaaccaatc gagcgtgaac ccgcataacc
    73981 agttatcgtt cgaccaaagc gcgcagatca tcatcagcca cgtcaccgag ggcgtgaaga
    74041 tcgccgagaa ggccctgtta cccaaggcgg ttatcagctt catccgtacg caccacggac
    74101 gtggcaaggc gaagtatttt tacaactctt tcaagaacca atacccggac aaaccgatta
    74161 acgacgagct atttacctac cccggcccga atcccttctc gaaggagacc gccgtactga
    74221 tgatggccga ttccgtggaa gccgcctccc gcagcttgaa ggaacatacc gaagagagta
    74281 tcagcgcctt ggtgaacaag atcatcgacg ggcagatcgc cgacggcttg ctaaagagcg
    74341 ctccgctgac cttcaaggac gtggagacca taaagagcgt attcgtagac aaactgaaaa
    74401 ccatgttcca tacccgaatc agctatccgg acttgaaaaa acaatagcga accagcatga
    74461 acgaccacct actctactta gcctcgacag ggatcgtagc ctttacctgt cttctggtca
    74521 gcggactgct gttgtcgctg aagaccttgc gggaaagcac gatccccaag taccggacgg
    74581 cctgcaagta tctcgccttg gcctcggcat tggtaggcat agggcatatc ttcatcttgt
    74641 cttccggcac ggacgagcga accatcatgg agttgttcta cttccccatc ctgctaatca
    74701 gcgcctcgca agcgttgctg ttcacgttcc tgctcaccct cttattcagg ggaaagaacg
    74761 tgacccggag gaatatcctc ctccacgcca tgcctacgat cgcgcttacc gtagcctaca
    74821 cgatcgcttg tctcttccgg gaggatgtcc atacgtatcg tttcgacgta tggtgggata
    74881 atattgggaa cccgcccctg ctgatacgta cgctcacgtg cctcgtatac cttgtccagc
    74941 tagggggcta tacgcatttt ttcttccggg agcgggcgat ctatctaggt aacctgaaac
    75001 agatacccca atcacccgag cgactggaat tgcgctgggt aacccgtgcc ttcctatggg
    75061 cgctgggtat cggcatcgcc gccgtgagcc tctgtttctt cccgaataat tactataaca
    75121 cggcggtcaa cttcgtgttc gccctcttct acgcctcggt atcgatccac tacgccaact
    75181 accattacac gtacgaccaa ctatacctgc ggctcaacct cgccccgcaa gccgacgccg
    75241 ataccgatcc caaccggatg gacctagagg atctgatcgg cgggttgctg gaaatcgagg
    75301 aggacgagtt gttccagcaa gcgcaaaact atatggccag ttcctcaccc ttcctcaacc
    75361 cgaatttcag ccggcaagac ctagtacgtg ccctcggtac caacgagaag tatctctcca
    75421 cctccatcaa ggacaagctg aacatcacgc tcaaggaata catcgaccgc taccgggtga
    75481 accacgcccg taccgagctg ttgatgccgg gcgacagccg gagcatggaa gagatcgctg
    75541 tcggcgcggg cttcaccagc tcccgcacct tctcacgtat cttccagaaa atactgggag
    75601 tcacccccgc ccaataccgg cggcaggcgc aataatgagc atttttccga gatctgtcct
    75661 cttttttccc ggatttgtcc tctcattctt accccgaacc ccgttctttg ccggcagtaa
    75721 tcacttaata aaggaatacc atggcagaac aaatcattct caacacagac ttgtacgata
    75781 acctgctcac cgagcgcaag ggcgactaca ccgccaagcc gcgcatcacc ggaacattgt
    75841 ataacacgga catcgccgca cgcatcgtgg ccgcacgtac cgagtaccaa cacggcacga
    75901 tcctcaacat cctcgacatg gccgacagcc ataaggtgca agccatcgcc gagggcaaga
    75961 gcgtggtgga cggcgtaggc caatacctcg tcaacgtgca gggggccttc gaaggcgaga
    76021 aggctcagtt cgaacccggg aagcacgccc tcggcatcac ctacaccatg ggcaagctct
    76081 tgcgcgagac cctcaagctg gtgaaggtgg tggtgaacgg cgtggcggcc gtaggtccgg
    76141 tgatcaatac cgtgaccgac tccacctcca aggccatcaa cgggcagctc agctccggcg
    76201 gagccctcgt gctgggcggc gtaaacctga agatacaggg tgatgatccc tccatcggtg
    76261 tctacctcac ccccaccacc gaaggggccg cgccgatgaa ggcacccgtg gtgatcgcca
    76321 actcgccctc gcaggtgatc gtgcagatgc cgacgctggc cgacgggcag tacaccgtga
    76381 gcctcaccac gcaatacagc ggaagccgta acgtaaaaga gccccgcacc tacaccttcc
    76441 ccatcatcct tatcgtagga gaaggcggtg ggggcgacag cgagagtccg gacgagatct
    76501 gaggacaacg ttgtccggca tgtccggaca acggctgcca agcatcgagg acaacggctg
    76561 ccaagcctgc cggaaaaaac aaccgattta taaaccctat tatacacata gaacatgaga
    76621 acatcattac atgacatcca cctaccggca aggcgaatat tcgccttgct gatcagtgtc
    76681 gcgacactga tcgccaccct cccgacagcg gcccgcgcgc aagcggaacc tcccggggca
    76741 ctcgaccttg ccaccctgcc gggcaccctg aacaataact ggtacatcaa cctcgcgtac
    76801 ctaaacggca cgtgggtgta caaagtaggg gcatccgaca cgcaggcccc gaccaccggc
    76861 acnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    76921 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nncctccgcc gatcccgaca
    76981 gcggcaaccc accggcgctg acgctgaaag acgccgtcat aacctcaagt ttcaaccagc
    77041 tcttctatat caaggccggc gcggaaccga ccctccggat cgagggggag aaccggatcg
    77101 agatcatgag cgacctcatc tataacttag gcacgctcac cctgaccgta gccgatgcgc
    77161 aggagataag ccaaggtatc ctaaacggat ctcccgcggg cacgggtacg ctcacggtct
    77221 atgcccaagc gccgctcagc atcggcgcca tctccaactt ccagaatgcc cggatgcatc
    77281 tggacggaga gatacatgtc atcagtaaaa caggtggctc agcctttaaa aacgacaata
    77341 cctcaccgga cgcgatcacg ttcggggata acgcacggat ccacctgcaa gcgaacgcgc
    77401 tctgcaccta tgtaagcggc tttatcgaac tggatttcga taccgccccg accgatggcc
    77461 ggacgctgtc cgttaccccg gcaggcgacg acgagccggc ggccaccttc gcgaccgacg
    77521 ggacctgctg gggttacgcc ttcctcgccg cggccgatac gcggtatacc gcctccctcg
    77581 acggcgagcg gctatatgcc ggcaggcgtt acagcgggtc ttcctataaa gacggagact
    77641 accccttctt ccggacagac ggggcatact gccgatactc cggcgccacc gccacccgcc
    77701 ccaccccgca gccgctcgac ctttccaagg actacggcta cggcagcacc cgcaccggca
    77761 tcgacctctt cttcgacccc gcggacggat ggtactgcga cgagaagatg ttcgacggga
    77821 cggtgacgac aaacggcagc tcatcctaca tcaacatccc cgccaccatc catgccgagg
    77881 gcgaggctac gcttacgctg gacaaggtaa atttccagct cccgacgggc acggccctca
    77941 cggtagcgag cgggacggtg acgctccaaa acaacaccta caacgccctc ctgtccggaa
    78001 cccacgcgct ccgggtagag acgggagcca cctgcctcat ctcgccgccc gccgacccag
    78061 ataacacctt ggcgcttaca gccgccgagc aggccatcca ccccgaaggc ggcggcaccg
    78121 tgaagggcct tgtccaactc acatggccgg aatctccgtc tggctacatc tacctcaaac
    78181 cggcggaacc ggcggagaat ccgaatggtc tgaccttcaa tattacaggc atgaagagca
    78241 tagccacgaa ctacccgctc tccttctacc tagagaatca gtcgacgggc ttgaaacagg
    78301 aaggctaccg ctccgacgac ccggagcaaa cctacctcag caccttcccc gccgcccatc
    78361 ccgaccggct gacaagctac acgggattgc gcgaaatcac gcccgcatgg atcgtgatcg
    78421 acaaggagac ggccttcgac gcgagcatgc cgggccaatg gctgcgcgtc accgagaagg
    78481 gtgtccttac ggtagggaag ataggagaaa atggagtatt tccactggtg aatgatctcg
    78541 agctgcagga cggcgggcag atccggttcg ccgatgacgg cgtgctagga ctcgtagcgg
    78601 cccgcttcac ccacctcttc cccaaccgca accaatggcg ggctaccacg ctagcggccg
    78661 ataatgccga caaattagcc ggcgatgcgg gaaccccttg ctacgtacgt accggatatc
    78721 ccgacgccac cgaccagact tggcagccgg cggatcccga caacctgtat atgcagttcg
    78781 ccgcgggtga ccccgtgctg atcgccggcg aaggcccgga gacagacacg ctgcgcctca
    78841 attacggcaa tacctacctc ttcaaggaca gccccgactc ccccgtcgag cccaccagcc
    78901 ccgccgagcc gctcaacatg ggcgtgttcc tcttcaaggg caatcgggcc tcgtacaatg
    78961 tggagatgcg aaacatatac gtcctcagcg acgacggcag ccgcttcgag ctgaaggacc
    79021 gggttaccct gcg
//
LOCUS       DBMDTB010000006        73360 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_155_length_73360_cov_11.260651, whole genome shotgun sequence.
ACCESSION   DBMDTB010000006 DBMDTB010000000
VERSION     DBMDTB010000006.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 73360)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 73360)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..73360
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_155_length_73360_cov_11.260651"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            57..1625
                     /locus_tag="ACZPB4_01905"
     CDS             57..1625
                     /locus_tag="ACZPB4_01905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HIR1097010.1"
                     /translation="MNQTIYPIGIQNFEKIRKDGYLYIDKTALIYQLAKTGSYYFLSR
                     PRRFGKSLLLSTLEAYFQGKRELFEGLAMERLEKDWEVYPILHLDLNARHYKDTAALT
                     SILNEFLEKWEALYGTEKQDRALEERFSYVIEQAYRQTGHRVVILIDEYDKPLLQNLH
                     DEKTQTQLRNMLKPFYGVLKTMDRAIRFALLTGVTKFGKVSVFSDLNNLMDISMDNRY
                     VEICGITEKEIHAYLEEELKELAETQELDYEETSQKLKERYDGYHFTAKSAGIYNPFS
                     LLNTFAKMEFGDYWFETGTPSYLVELLKHTHYDLYEMANTETDADVLNSIDAASKNPV
                     PVIYQSGYLTIKDYDPEFGIYRLGFPNREVEEGFVKYLLPFYTSVSAPKTPFEIGQFV
                     REIRSGDYDAFFRRLQSFFADTPYEVIAGQKPERDTELHYRNVLFIVFKLVGLYTQVE
                     YHTSQGRIDLVLKTDRYIYVMEFKLNGTAEEALRQIEERQYALPFASDPRQVFKIGVN
                     FSSVTRNIERWLVE"
     gene            1641..3413
                     /locus_tag="ACZPB4_01910"
     CDS             1641..3413
                     /locus_tag="ACZPB4_01910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6057 family protein"
                     /protein_id="HIR1097011.1"
                     /translation="MNWKQTLFWSFSTAAIFYYFLLFGVFVFVGQEEMQLFIPEWWYI
                     REFLFQPGGFCAVAGQWILQYYRQPMSAVVLHTVLLVGCGFMVYRILRCFSDKTYLLF
                     LSLLPVLYLVKMSIHGEYLVDGTVGVVLMLLALSVSLKVRRAGSIAGYGIASTLFLCG
                     LTGLLSVCYAFLYTLLALLRYKTSRQRLAAAACLIPALFIYLFSGWLGIPVPLSDGWM
                     PEAYLEIQRLPHYYMYRVWTFFTLSIVGVALFARFVPVIGEKSKWMDRVALVVCLITA
                     LVSIRFCLPEPWHAQRMMLDELSFLARERQWDAIIDKYRGKQIYNYVSLNYLNMSLAH
                     KGELADRMFTFDQKGTKSLCADWNQTFYMDRLLSDVHFLVGDVSLSESFAMDGFTQAK
                     RKGSARMMQRFVQVCLIRGEVALAKKYLDLLAAMPFYKDWACRYAIYLVHPELMDKDP
                     ELSDKYMPVEKRDRLSLSVPVDSLWSGYNLPDHRIGWEYRGCYYLLGKKLDAFGRFLE
                     ETPFMKGEPIPRHFQEAGLLLADKDSISLSSYSIQPEIVDRYREFKQVLGRSANQVDV
                     SSMYRQFGDTYWYYYYFKIFKGEE"
     gene            3413..4882
                     /locus_tag="ACZPB4_01915"
     CDS             3413..4882
                     /locus_tag="ACZPB4_01915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolB family protein"
                     /protein_id="HIR1097012.1"
                     /translation="MKRLSICWIIGCLLGLVACRPEVPAQAEQGETDVFPDYREVTVP
                     VNMAPPNFKLVNQQLQGITRLKTMNRELIIAADHGVFNLPETDWKVLSQDAQGKQIDV
                     TVYFREPQSDWKQMSFPIYVSRDSVDAYLVYRRIFPGYRMWNEMGIYKRCVENYVEKS
                     ILDNQSTNNSCMNCHAFCERQGEQMLFHQRGSHNGTYLIDHRQVKKIALERDGKPASF
                     VYPYWHPSGRYVAFSTNETHQDFHLSDENRIEVYDVESDVLIYDTEKERVFSSPLLAS
                     MACYETFPTFTPDGNYLLFCSADSVCMPENYRDVRYNLLRVAFDPEDGSIGTQVDTLY
                     NAREAGRSVKFPRVSPDGKRLLYTVSDYGNFSIWHKDADLYMLDLSTGAIDSLPEVNS
                     PDVESYHSWSGNSRWFVFSSRRDDGLFTRPYLVHVNERGQCGKPFLLPQASPDYYECS
                     LFSFNVPEFIHTPVIISKERLVEASRKEDTTTIKHIEGI"
     gene            4946..5872
                     /locus_tag="ACZPB4_01920"
     CDS             4946..5872
                     /locus_tag="ACZPB4_01920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase domain-containing protein"
                     /protein_id="HIR1097013.1"
                     /translation="MRKVHLISVTEPLVLDLALALREKGYEVSASGCGLTEEMIGRLH
                     NAGCTCYGDGWFPEKLIKDIHSVVLGAKVKQDNPELLRAKELGMLIQSIPEFIFQRTR
                     SKTRVVVAGSRGKKTIISMMVCALRRQKLAFDYALTSKVDSLPNRVHLSYEARIALIE
                     GDEHITSALDKRFQLEFYRPHIAILTNLSWSTETDHATPEAYLSTYQSFSVSIEREGK
                     LIYFGGDDTVSQLAGDVRSDITAIPFEEHPVVEKDGQTFLHTRYGDYPVRIPNRYFLI
                     NLNAARLACRQLGVKDADFYQALSEYSLSLPI"
     gene            5869..6417
                     /locus_tag="ACZPB4_01925"
     CDS             5869..6417
                     /locus_tag="ACZPB4_01925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4924 family protein"
                     /protein_id="HIR1097014.1"
                     /translation="MIIARQKRKENIAEYLLYMWQVEDLIRANKFDMDSINRTVIAHY
                     DQPEEVKKEIAQWYEELIEMMRSEGVMEKGHIQLNKNVIITLTDLHLRLLKSPKEMVY
                     SAAYYKTLPYIVQLRAKSGGEDLPELETCFAAVYGYLLLRMQGKEVSAETLEGIKQIS
                     SFLALLAEKYREDMKGELKLED"
     gene            6432..7295
                     /gene="rfbD"
                     /locus_tag="ACZPB4_01930"
     CDS             6432..7295
                     /gene="rfbD"
                     /locus_tag="ACZPB4_01930"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008831 - dTDP-4-dehydrorhamnose reductase
                     activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HIR1097015.1"
                     /translation="MKTVLVTGANGQLGSSIHARISQYPGYNFLFTDIDTLDICDKEA
                     VRKYVLENDVQYVMNCAAYTAVDKAEEHEDLCMRINRDAVRNLGEAAHAVGAKVIHVS
                     TDYVFDGTSCRPYLESDATCPVSVYGRTKLAGEQALMEVCPDSVIIRTAWLYSEYGNN
                     FMKTVLRLGKERDELRFIFDQVGTPTYAGDLAVAMLTVLERAEAGKFIPGIYHFSDEG
                     VCSWYDFTVKILQIAGMNNRVIPIETKDYPTPASRPHYSVLNKGKIKSTYGLTIPHWE
                     TSLAYCMNNKV"
     gene            7325..8905
                     /locus_tag="ACZPB4_01935"
     CDS             7325..8905
                     /locus_tag="ACZPB4_01935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HIR1097016.1"
                     /translation="MSQYSEEIERRRTFAIISHPDAGKTTLTEKLLLFGGAIHVAGAV
                     KSNKIKKTATSDWMEIEKQRGISVATSVMAFDYSDHKINILDTPGHQDFAEDTFRTLT
                     AVDSVIIVIDIAKGVEAQTRKLMEVCRMRKTPVIVFVNKMDRDGKDPFDLLDEIEEEL
                     QIKVRPLSWPIDMGQRFRGVYNIFEQKLNLYTPSKQYVTENVEFKDITSPDLETYIDP
                     TQAAKLREDIELIEGVYPEFDVNTYLDGDIAPVFFGSALNNFGVKELLDCFIRIAPSP
                     RPIHAVERVVDPNEDNFTGFIFKIHANMDPNHRSCIAFVKICSGRFERNANYKHVRFG
                     KMMRFSSPTAFMAQKKEVVDEAFAGDIIGLPDTGNFKIGDTLTSGEELHFKGLPSFSP
                     EMFKYIENADPMKAKQLNKGIEQLMDEGVAQLFTNQFNGRKIIGTVGQLQFEVIQYRL
                     LHEYAAQCKWEPISLYKACWIESDNKQALENFKKRKAQYMALDKEGRDVYLADSSYVL
                     MMAQQDFPDIKFHFTSEF"
     gene            8907..9914
                     /locus_tag="ACZPB4_01940"
     CDS             8907..9914
                     /locus_tag="ACZPB4_01940"
                     /EC_number="2.7.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HIR1097017.1"
                     /translation="MKSQFSILCLLVNLLLISCEQAPQYYEVSGRLHTPYHIKFEHTK
                     PLDKEIDEQLKYFYHLFNAFDSTSVISQVNQNRDIRVDTLFQKVFKKALEVSAETNGA
                     YDVTCAPLINLWGFGFSRKDSVTPAHIDRVRQFIGFQKVRLEGDRIVKDDPRLMMNFS
                     SLADGTVCDMIAQMLEKKGVRNYLVEFGGEMRVKGVNPSGMDWRLGITKPTDDAAGMN
                     QELEQIVSFPKPLGMATSGNYRNFYIKDGRKYAHTIDPREGCPVQRDILSATIVAPDA
                     MTADAYATAFMVLGSEEAKSLCAKVPGLEYFIICSDSIGDGYHPEYSEGFRRYLVTAD
                     K"
     gene            complement(10046..10738)
                     /locus_tag="ACZPB4_01945"
     CDS             complement(10046..10738)
                     /locus_tag="ACZPB4_01945"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HIR1097018.1"
                     /translation="MIYKSIFIDLDDTLWDTYHNNKECLEELYTDYHFNRYYASFEAF
                     FDIYMPHNLDLWAKYRSGEIDRQTLILDRFLYVLRPLGIEDKKTVLSVNNDFLQRTTT
                     KTRLVPGAIELLEYLRPSYRLFILSNGFREVQFKKLSNAGLAPYFERMILSEDANIQK
                     PHKGIFDFALKNTNSRRSESLMIGDSWEADIIGAYQSKIDQIWLNPEGLPADGFTPTH
                     TVRSLEEIKSIL"
     gene            complement(10738..11610)
                     /locus_tag="ACZPB4_01950"
     CDS             complement(10738..11610)
                     /locus_tag="ACZPB4_01950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009859711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cbp1 family collagen-binding glycoprotein
                     adhesin"
                     /protein_id="HIR1097019.1"
                     /translation="MKKVLLVCVCTAMLASCGQNSADYKKLKAENDSLRIENTKNTDE
                     LNDMLSTLNDIESDFQSIRDAENYLTIQQQTGGELNQSRRDQIKQNMQLISETLKKNK
                     EQISQLEEKLKKSGIQSSALRKTIDRLSSELDQKATMIVALQEDLAKKNVRIQELDEM
                     VSSLNEDVESLATTAAAQSEKLNAQDKALHTAYYCFGTSKELKEQKILSGGGLFSKSK
                     VLQSGFNKDYFISIDIREVKEIPLFASKAKLKSNHPEGSYEFVEDEDGNLTLKINDEK
                     AFWSLGKYLVIEVG"
     gene            complement(11630..12334)
                     /gene="rsmI"
                     /locus_tag="ACZPB4_01955"
     CDS             complement(11630..12334)
                     /gene="rsmI"
                     /locus_tag="ACZPB4_01955"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HIR1097020.1"
                     /translation="MAKLTVVPTPVGNLEDMTFRAIRVLKEADLILAEDTRTTGILLK
                     HFEIQNKMQSHHKFNEHKTVEQIAARIKGGENIALVSDAGTPAISDPGFMLVRECVRQ
                     GVDVECLPGATAFVPALVASGLPNEKFCFEGFLPQKKGRQTRLKELALEYRTIIFYES
                     PFRLLKTLTQFAEFFGTDRQVSVSREISKLHEETVRGSLEEVIQHFTVNEPRGEIVIV
                     LAGLKDKKDKETEKDV"
     gene            complement(12344..13039)
                     /locus_tag="ACZPB4_01960"
     CDS             complement(12344..13039)
                     /locus_tag="ACZPB4_01960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097021.1"
                     /translation="MANKEKIDYLLIDIRELEKLVAGMRDAEIYLASFFNQTFQLTHK
                     VLKELHTLEEFQLEALRKQMEEHQRLIDSIPVSKPLQMPEVQPAPEVSPTIEVVQVQE
                     PVVEEPIVVEPIVEKVIPEEKIVQETIPLKEIEIPHKTILADKSSISLNDILEKKNLS
                     DFRKAFSLNDRFRFRRELFGGNEEKMNKAISDLNDLSSYEESVTYLNKVLNWNIEDAS
                     VADFIKLLEKRFS"
     gene            complement(13149..14564)
                     /locus_tag="ACZPB4_01965"
     CDS             complement(13149..14564)
                     /locus_tag="ACZPB4_01965"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0032508 - obsolete DNA duplex unwinding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HIR1097022.1"
                     /translation="MINSYISQQIERNFPYKPTDDQFLALHTLTEFLLSEEPDSLLLM
                     KGYAGTGKTSLVGALVKTLNELKQKTFLLAPTGRAAKVFSGYAGQKAYTIHKKIYRQR
                     AFSNEPTGFMPADNLHKDTLFIVDEASMIANEGLDSFVFGSGRLLDDLIQYVYSGGNC
                     RLILMGDVAQLPPVMQTESPALNPEILRGYNLQVWEIALTQVVRQSEDSGILFNATRL
                     RDALRNHTVEIFPKLQLKGFSDFTKVNGDELIEEISSAYSRDGMEETMIISRSNKRAT
                     IYNNGIRNRILYREEELSSGDRLMVAKNNYYWTANCKEMDFIANGEIIQVMRVRRVTE
                     MYGFRFADITARFQDYDLEIDLKILLDTLQTDSPALPKELNDKLFYTILEDYEDIPTK
                     AGKMKKMKVDPHYNVVQVKYAYAVTCHKAQGGQWMNVFLDIGYITEEMLGEDFYRWLY
                     TAFTRATHHLYLVNLPDEFVE"
     gene            14658..15293
                     /locus_tag="ACZPB4_01970"
     CDS             14658..15293
                     /locus_tag="ACZPB4_01970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097023.1"
                     /translation="MKVTLKILLAAAVVLLVYMCYKSVTGPIEYDDQKTIRDNAIIAR
                     LIEIRKAQIEYKNMYKTHAGSFDDLEKFLNTDKLPFLIKEGVLTDEQLEKGMTEAEAV
                     KKGLIRRDTMWVLAKDTLLGKNYDVAAMRYVPAVPGEKITFKMDTATLKSGSGYEIKV
                     FACEVPYKEYLRDMDAQLTYNLIDKAEKQGKFPGLRVGSLEEINNNAGNWE"
     gene            15306..16130
                     /locus_tag="ACZPB4_01975"
     CDS             15306..16130
                     /locus_tag="ACZPB4_01975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3822 family protein"
                     /protein_id="HIR1097024.1"
                     /translation="MTISIPDTLTTDNSEKYIVSIRLRSGGLSFSGYDPSAGGSFFYR
                     ETEFDRAVSFISSLKEFFFAHEFLTWTYKRINVICVSPEYSLVPDNYWGDGKEGRLLD
                     FSFSTLELHCLTDTLKEQQAKLVFGVDEEVYEFCSRSLLHPFFSHYMTSPLTLWTKES
                     SASLPRQMYVVIERKRMDVACYAQGKLLFVNSYPIDQSDDIVYYILYVWKQAGLDQEK
                     DQLLLAGESSSRMRVLERLRAYLRHVKPVEIPSEAYLLGTDVTKAPMDLISLLICE"
     gene            16121..16678
                     /locus_tag="ACZPB4_01980"
     CDS             16121..16678
                     /locus_tag="ACZPB4_01980"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RsmD family RNA methyltransferase"
                     /protein_id="HIR1097025.1"
                     /translation="MRIISGIYGRRRFDVPSSFSARPTTDFAKENIFNVVNNLVDLEG
                     MDALDLFAGTGSISFELISRGCRNVTAIEKNNAHASFIAKVAKELKTDALALIRGDVF
                     RYLNSAPKQSFDFIFADPPYALPELPEIPALVFERDLLRDGGIFIMEHPKTNDFSSLP
                     YFYQHRVYGSVNFSIFLKEGEKTDA"
     gene            complement(16650..18086)
                     /gene="cls"
                     /locus_tag="ACZPB4_01985"
     CDS             complement(16650..18086)
                     /gene="cls"
                     /locus_tag="ACZPB4_01985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HIR1097026.1"
                     /translation="MLAAIHIQLIVGTIFIILYSVTILGLVLVIITENRNPLKTIPWV
                     IVLLLAPGIGLLFYFFFGQDNRKQRIISRRTYKRIMKRPQEGKLPQDACVVPDPYKPL
                     STLLTNTNQSSLLYGTQITIYTNGTDKFKDLLEEIQKATHHIHIQYYIFCDDEIGKQV
                     QQLLIKKVKEGVKVRVLYDDVGCWNVKDGFFKEMKEAGIEVYAFLRVAFPVFTSKVNY
                     RNHRKIIVIDGKVGFMGGMNIADRYDKGTSWGTWRDTHFKFVGKGVHGLQSVFLIDWY
                     VVSKKLLNDRIYYPAAQIYSDNIMQIATSGPVGQWRTLLQATIFMIANAKKYIFIQTP
                     YFLPTEGLNQALQTAALGGVDVRLMLPKRSDTRSANMASHSFIDEMVKAGVKVYLYKP
                     GFLHSKLVVSDDALTSIGSANMDFRSFEHNFEINAFVYQKEFALQMKRIFTHDMHHCE
                     RLIPSRWLKRPLKQRMAESFMRLFSPLL"
     gene            18663..19934
                     /locus_tag="ACZPB4_01990"
     CDS             18663..19934
                     /locus_tag="ACZPB4_01990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097027.1"
                     /translation="MESNSRDMNRKSSIRAILLRKECLLFFLLLLPMFTKAQYNKVYA
                     DITANMLVDMGFENVVWSEDEKERVYVLENTPWRLQGVGLAHAIDRIQKTGLPEKGKS
                     CRIVVLDNNIPQISLIYTANPDSLKAAPGSYAARSAWDATYDLGDSWDKVKKEYRMNS
                     SLFKVDVVVYPELYLKNLIITQIYQVLFNLSPAIEVSFWNGMKLTAQMVFPIYNDGYG
                     KRMDKIHPGTIALSQSFRLPMRTFARVSVGLFDSDRYGIDLKAVHYFKDERFSVEGRI
                     GCTGTGYWNGFEFHYGKHQRITWSLGGSFYWPKYNTQISLKAEQYLLHEVGGRIDLIR
                     HFRYCSIGFYAMKAQGALKNGGFRFQVALPPYKYKRKYARVTTSDNWGMSYNAGNERY
                     YYKNYYALPEDNMMKQNQFNPYFIKSELLNF"
     gene            19946..22201
                     /locus_tag="ACZPB4_01995"
     CDS             19946..22201
                     /locus_tag="ACZPB4_01995"
                     /inference="COORDINATES: protein motif:HMM:NF025006.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase-like regulatory
                     domain-containing protein"
                     /protein_id="HIR1097028.1"
                     /translation="MRTITKLQTLLVLFLTTAMIGFAGCKDDDGDVPGPTPGNEATYA
                     ISGKVTDVDGAAMADVNVALSGAKSMSAKTAADGQYTFDLGKNAAGAYKVTFSKEGYI
                     ERSYDITVKKVESGLGENIQNAVMEKGTTPEPTPEYKKAKYFLTVSVKDEAGKDITAS
                     DLSVLVKLGDKEIAKENKASFELSDVATGTYDITATASGYEKTVAKVVVSPVEDQEKA
                     EGDGDTFDVKYPANLVLKASTPTPTGPSYIVEGDVKDVNGKAVNATITLSGALTKMIY
                     RSGFETQTVTGSHYRFVIPQDAVTAQMRFTIRVVAEGYAAYSYNFTLDELKPGETANV
                     IADFHLTPATPTPDPTPTPDPTPDPDPVTKGGEVSKPITEVNPEIGVEQVGKVEEKIE
                     ANQEKKVEVKDETGKTVEVAVKIPEAVADKYESGANVAVANPETFAASLGKIESVVED
                     KSEVDEISFSTEGSNTGVVIVTPNNTTEDFSIKRDATVELTVNSEKAAEIETGTDAST
                     VAESGSPAAAVTRIYTGKPDGTVIIPAMVIKASAPADFKNVSDMPLNLLYKNGDNWVV
                     DKDAKVELKNGQLNIPVAHYSQFSAGLLMAVKTTTAPSDSTFFIEKSEFGEYNKMVSV
                     EFTYNATFLNNKDLDKAVLSVPYGNAAKDYLKNCLGKKINADGGLISFKKSYDVKVDE
                     GMTLKGVNITVKYAAKEYVVYYLNKGGSLESVSVTVLSVKEANPAPLYEQSHGHGHGN
                     GNNAGGGIFGK"
     gene            22268..22999
                     /locus_tag="ACZPB4_02000"
                     /pseudo
     CDS             22268..22999
                     /locus_tag="ACZPB4_02000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773839.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YjbH domain-containing protein"
     gene            complement(23104..24078)
                     /locus_tag="ACZPB4_02005"
     CDS             complement(23104..24078)
                     /locus_tag="ACZPB4_02005"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIR1097029.1"
                     /translation="MQDIINPIDRALLKAELTKEKRLRSTNKSKNEIYIVTAHDSPNV
                     MQEIGRLREVAFRYYGGGTGFPVDIDEYDTMEDAYRQLIVWSPEDEQILGGYRFLCGS
                     DVKFDENGKPILATSHLFNFSEKFIKEILPYTVELGRSFVALEYQSTRSGAKGLFVLD
                     NLWDGLGALSVVDPSLRYYFGKVTMYNTYNQEARNMILYFLGLHFPDADQLITPVYPL
                     ETNMDVEKMRSLFPHDNFKDNYKVLNQEVRKFGINVPPLVNAYMSLSPKMRVFGTAIN
                     HEFGEVEETGILIAINEILEDKKKRHIETYLEEEYKSAELIRKNFIGE"
     gene            complement(24091..24915)
                     /locus_tag="ACZPB4_02010"
     CDS             complement(24091..24915)
                     /locus_tag="ACZPB4_02010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HIR1097030.1"
                     /translation="MAKQGVTKIDIKQVLAQKAPKASRKIPGFIVDYLIRTVHQEELN
                     DILTRYHDKEGVDFMRELIGYFDLTLDLVHAENIPTEGRYIFASNHPLGGLDGICLSA
                     VIGSRFEGRIKYPVNDLLLYLSNLKSIFVPINKHGTQGKDNARMLEEAFASDDQIITF
                     PAGLCSRKIGGKIQDLEWKKSFIQKAVQYKRDIVPVYFDGKNSNFFYNLARIRKALGI
                     KMNYEMIYLPDEMFRSKHKTFRIYFGKPIPWQTFDNSKKPAEWAEWIKNKVYKLKD"
     gene            25392..26309
                     /gene="rsmH"
                     /locus_tag="ACZPB4_02015"
     CDS             25392..26309
                     /gene="rsmH"
                     /locus_tag="ACZPB4_02015"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0000154 - rRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HIR1097031.1"
                     /translation="MEEKDSCYHVPVMLRESLEGLDIRPDGIYVDVTFGGGGHSCEIL
                     KRLGSEGELYGFDQDADAEHNIPADPRFTFVRSNFRYLYNFMRYYGESGEVDGLLADL
                     GVSSHHFDDKDRGFSFRFDGALDMRMNTRAGQTAADIVNNYTAEALADVFYLYGELKV
                     SRKLASVLVKARETKKIETIGDFLEVIKPFTGKDKEKKFLAQVFQALRIEVNDEMRAL
                     KEMLRSTLRVLRPGGRLVVITYHSLEDRLVKNFLKTGNFEGKCEQDFFGNVRSPFRLV
                     NNKVIVPTDEEVERNPRSRSAKLRIAEKV"
     gene            26322..26675
                     /locus_tag="ACZPB4_02020"
     CDS             26322..26675
                     /locus_tag="ACZPB4_02020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsL-like putative cell division protein"
                     /protein_id="HIR1097032.1"
                     /translation="MEENGQHKKTRKKEKRLSFWYILGGGVLKEDFILRHTRMIVLLV
                     VLAFFFIGNRYTCMQKLREIDRLQQQLRDVRFEALSISSELTGNSRQSQIELLIEEQG
                     IDLEGAKTPPYELYK"
     gene            26694..28889
                     /locus_tag="ACZPB4_02025"
     CDS             26694..28889
                     /locus_tag="ACZPB4_02025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HIR1097033.1"
                     /translation="MSEENEPKEIEPKSSRILFCYFVVVLLLGLVAVGILFRAFDTAF
                     VERDKWMKVAESQKRPNRLVLPGRGNIYSSDGKLMATSVPRYYMYIDFKADAYTPAKD
                     AKYNWLDTFKTSKKDGVDSLAFYLSRKLKDRTPAGYKAYLLKGLSGKSRQFPIYAGKV
                     SYSDLKEIRKFPFLRLGRYKSGFYTKEMVQRQKPFGTLASRTIGDIYGEIEEGGTTKG
                     KNGLELQYDSLLRGQAGLSSVRRVGGGWTNVIEVDPVDGMDIRTTIDINIQDITEKSL
                     VDKLKAIDAESGTAVVMEVETGEIKAITNMGRIREGVYGETKNHAVADEIEPGSTFKV
                     ASIMVALEDGLCNPGDTVDVGNGIYMYKGARMTDHNMNKGGYGRISVEQAIWYSSNIG
                     VAKTILKGYSDNPTKFVEGLYRIGMNADLRLEIPGAGRAKIRRPDDTTRYWSKTTLPW
                     MSFGYETQVPPINTLAFFNAIANDGKMVRPMFTKEILHNGKTVQSFSTEVINSSICSD
                     HTLALIKDMLLGVVEKGTGKAVHSDIVRIAGKTGTAQIATGGVYRTSGHQVSFCGYFP
                     ADHPKYSCIVVIRRPRIGYPSGGTMSGGVVRAIAEKIYASHMSFDVRDMERDSMAVMV
                     PRVKGGDLRAVEDVLDELDIKADTDSLETKWVVASAEQEENKVKLSDLTIREGLVPRV
                     VGMGAKDAVFLLEQAGLRVSLSGVGRVVSQSIQPGQRVSKGQTVLLTLK"
     gene            28892..30352
                     /locus_tag="ACZPB4_02030"
     CDS             28892..30352
                     /locus_tag="ACZPB4_02030"
                     /EC_number="6.3.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HIR1097034.1"
                     /translation="MELRDLIGALEAPMLMGADNVDITNIQSDSRRVTKGSLFVAVRG
                     TAVDGHAYMDSAIEKGAVAIVCEEAPSYLEGRCSFIVVKDSAEALGLLVSRWYGDPSG
                     KLVLVGVTGTNGKTTIATLLYEMFRKMGHKVGLLSTVCNYIDGEAVPTDHTTPDPLTL
                     HSLMARMVEAGCEYAFMEVSSHSIDQRRISGLSFDGGIFTNLTRDHLDYHKTVENYLK
                     AKKKFFDDLPAGTFALTNADDKSGLVMLQNTKAKKLTYSLRTLADFKGKILESHFEGT
                     DLIINGREVMVHFVGRFNAYNLLAVYGAAVSLGKDPEEVLIVLSTLRSVSGRFETIQS
                     PLGYTAIVDYAHTPDALTNVLNGIHEVLDGKGRIITVVGAGGNRDKGKRPLMAKEAVK
                     LSDQVILTSDNPRFEEPDDIINDMVAGLTKMDMERALCITDRTQAIKTATMLAKKGDV
                     ILVAGKGHEDYQEIKGVKHHFDDREKLREIFSTQQS"
     gene            30366..31625
                     /gene="mraY"
                     /locus_tag="ACZPB4_02035"
     CDS             30366..31625
                     /gene="mraY"
                     /locus_tag="ACZPB4_02035"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HIR1097035.1"
                     /translation="MLYYLFNYLDQLDFPGAGMFKYVSFRSGLALILSLFISTAIGRR
                     IIDKLQMLQIGETVRNLGLEGQMSKKGTPTMGGIIIIIAILIPTLLCAKLNNIYVILM
                     LVTTVWLGALGFADDYIKVFKKNKEGMHGRFKIVGQVGLGLIVGLVLFMSPDVVIKEN
                     MEVRHDNVIEEVRYHTVETKSTKTTIPFLKNNNFDYANLVNWAGDYKEEAAWLVFVLM
                     VIFVVTAVSNGANMTDGLDGLAAGTSAIIGVALGILAYMSSHFEFASFLNIMFIPGAE
                     ELVVYAAAFIGATVGFLWYNSYPAQVFMGDTGSLTLGGIIAVFAIIIRKELLIPILCG
                     IFLVENISVMLQVAYFKYTKKKYGEGRRIFKMAPLHHHFQKPGNAGIQALIQKPFNVV
                     PESKIVVRFWLIGIILAVMTIVTLKMR"
     gene            31629..32966
                     /gene="murD"
                     /locus_tag="ACZPB4_02040"
     CDS             31629..32966
                     /gene="murD"
                     /locus_tag="ACZPB4_02040"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HIR1097036.1"
                     /translation="MSKRMVILGAGESGAGAAVLAKAKGFDVFVSDKSSIKPKYKEML
                     DNHGIRWEEGQHTEADILNADEIVKSPGIPDKAPIIQLLKKQGTPIISEIEFAGRYTD
                     SKMICITGSNGKTTTTMLTYHILKEAGVDVGLAGNVGNSLALQVAEDPHAVYVIELSS
                     FQLDNMYDFRADIAIILNITPDHLDRYNYEMQNYVDAKFRILQNQTKDDAFIFWNDDP
                     IIAREIAKRHPEATLYPFAETYENGVKGYTENNQVVIETVNGTFTMEQDLLALTGTHN
                     LYNSLASGIASKIVDIHDEKIRASLSDFTGVEHRLEKVLRVRGVDYINDSKATNVNSC
                     WYALQSMTTPVVLILGGTDKGNDYSEIEELVNKKVHSLIFMGVDNTKLHAFFDGKVAN
                     IEDARSMEEAVAKAYKMAHKGDTVLLSPCCASFDLFKSYEDRGDQFKACVRNL"
     gene            32978..34285
                     /locus_tag="ACZPB4_02045"
     CDS             32978..34285
                     /locus_tag="ACZPB4_02045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008955 - peptidoglycan
                     glycosyltransferase activity [Evidence IEA];
                     GO_function: GO:0015648 - lipid-linked peptidoglycan
                     transporter activity [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HIR1097037.1"
                     /translation="MDLASKLFKGDRVIWIIFMFLCLISVVEVFSATSTIAYKNANHW
                     APIVRHATFLLGGFVMVLLLHNIPCRFFSAFIILLPVSMLMLIVTPFIGVDANDAHRW
                     LEIMGIQFQPSEFGKLACVVFVAFLLSKRGKLTENQIFKYILIGVGLTCVLILPENFS
                     TAFMLFGVCFLMMFIGQLPFGKLAKLAGILMLALVLFLVLLKFTPAAITQYLPDRFVT
                     WQGRLERFFDGHKDNLDESGTYKITDDNYQVTHAKIAIARGGVLGQMPGHGQQRDFLP
                     QAYSDFIYAIIIEELGIVGGIFVLLLYIMLLVRVGMIARKCDKSFPKFLVLGCGLLVV
                     VQALANMAVAVNLVPVTGQPMPLVSRGGTSTLISCIYFGIILSVSRFGANIGNEDEEE
                     EDTENPENPSDEPSGETINQAVEGEKEDNPLSAVETITVESKV"
     gene            34282..35388
                     /gene="murG"
                     /locus_tag="ACZPB4_02050"
     CDS             34282..35388
                     /gene="murG"
                     /locus_tag="ACZPB4_02050"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050511 -
                     undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HIR1097038.1"
                     /translation="MRKYRIIISGGGTGGHIFPAISIANTFKKRFPDAEILFVGAEDR
                     MEMDKVPAAGYKIVGLPVSGFDRAHLMNNVKVMARLAKSLRLARKTIREFKPDIAVGV
                     GGYASGPTLWMAASQGVPALIQEQNSYAGVTNKLLAKKASKICVAYEGMEKFFPADKI
                     VITGNPVRQDLEEALSKKEEALAFFGLSPEKKTILVVGGSLGARTINRSIQGDLDKFF
                     ASDVQVIWQTGRYYYSDASKHLKAYRGMPVWCSDFITRMDYAYSAADLVISRAGASSI
                     SELCLLGKPVVLVPSPNVAEDHQTKNALALVHKDAAVMIADKDAEKDLVPTALKIVHD
                     DERLHTLSRNIETLAQRHSADRIVDEIVKIIDKK"
     gene            35394..36782
                     /gene="murC"
                     /locus_tag="ACZPB4_02055"
     CDS             35394..36782
                     /gene="murC"
                     /locus_tag="ACZPB4_02055"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008763 - UDP-N-acetylmuramate-L-alanine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HIR1097039.1"
                     /translation="MDINKVTAVYFVGAGGIGMSALIRYFLAKGKRVGGYDKTPSDLT
                     EELKKEGADIHYEDNVALIGEAFKSPDDTLVVYTPAVPESHTELTYFRAHGFEVMKRA
                     RVLGEITKSSRGLCVAGTHGKTTTSSMLAHLLKQSPVDCNAFLGGILKNYESNLMLSD
                     TSDFTVIEADEFDRSFHWLTPYMAVITSADPDHLDIYGTAEAYRESFEKFTSLIRPDG
                     CLLIKKGINVTPRLQEGVKKYTYSVTEIADFYAENIRICDGNITFDFVGPEIRIPDVE
                     LGVPVKVNIENGVAAMAIAWLNGVKPEDLKKGMATFAGPRRRFDFHLKTDQVVLIDDY
                     AHHPAELRQSILSVKELYAGRKVTGIFQPHLYTRTRDFAGDFAASLSLLDELILLDIY
                     PAREEPIPGVSSRIIFDKVTIPSKTLCKKEELLDVVAAGKYEVVLMVGAGNIDRLVEP
                     VKEILCKQIRKP"
     gene            36779..37507
                     /locus_tag="ACZPB4_02060"
     CDS             36779..37507
                     /locus_tag="ACZPB4_02060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HIR1097040.1"
                     /translation="MIRIISIVVATLLFCYIVFVSFFFREIRQDSICQDLQVVVKDSL
                     DKHFVSESDLVSILKKAGLDPIKRSMADVNTDRIETELLKNEMIAQVEAYKTPSGIIK
                     LEVMQKMPILRIMGVRGSYYVDNLGTTMPISRRYAAHVPIVSGYVEKELAVTDLYKFA
                     LFLQENEFWNDQIEQIYVYPDNDIELIPRVGNHRIMLGTLDEFEEKLANLKLFYEQAI
                     PKVGWEKYSMINLKYKNQIVCTKK"
     gene            37513..38871
                     /gene="ftsA"
                     /locus_tag="ACZPB4_02065"
     CDS             37513..38871
                     /gene="ftsA"
                     /locus_tag="ACZPB4_02065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HIR1097041.1"
                     /translation="MAYTDFIAAIDLGTSHMVGMVGTKNATGALSIIAYEVENSGTCI
                     RRGCVYNVKETASKIKRLILKLENKLGGTKIGQVYVGLGGQSLRSIEHTVCKVLGTEG
                     VVTEEIIDSLYQECKDYRPDMLTVLDVVSPSYFLDDKPESNPVGVPCSRIEARYKLIV
                     GRPSLKLNIVNSISEQAKIEIAGILVSPLALGDVVLSDNEKDLGCALIGFGAGVTTIS
                     VYKGGKLASLSVVPFGGNLITKDITNLRVVESEAERLKITYGSAKADRDNDMTIQVSL
                     ADGMGLREIKLAELNGVIEARMDEILENVYARLEATGLMSVLGAGIVITGGGAALKNL
                     PAVMSERLKMEVRYSAVRKGVVASGDLVVASNPEYAVAVGLLAKGTKNCALYIPPKPE
                     PKIEPVVEPEPTVEPTPEPEPVKEKPKKEKKKGPGLFGRLTKGIDTFGKTLFDDDDNE
                     SK"
     gene            38905..40269
                     /gene="ftsZ"
                     /locus_tag="ACZPB4_02070"
     CDS             38905..40269
                     /gene="ftsZ"
                     /locus_tag="ACZPB4_02070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HIR1097042.1"
                     /translation="MDDTILNFNYPTDTPKIIKVIGVGGGGGNAVTHMYKEGIHDVTF
                     VLCNTDNQALNRSDVPIKLLLGREITQGLGAGNKPERAMMAAEESLDDLRGMLNDGTK
                     MVFITAGMGGGTGTGAAPVIARIAKDMGILTVGIVTIPFLFEGERKIIQALNGVEEIA
                     KNVDALLVINNERLREIYSDLSVMNAFGKADDTLTIAAKSIAEIITLPGIINLDFADV
                     NTTMKDGGVALMSNGFGEGEGRVRQAVEDALNSPLLSNNDVKNAKKILFNVYFSEEAE
                     LRMEEMNDVHNFMSEFNRDIEVIWGTAVDNTLGNKVKMTILATGFTMDDIPLIADKRR
                     NEAAQMTEEELRLEEERIEKERKERDLIGKYYGASAQKAGRFTSRAKAVVLTQEELDD
                     DALIALIEDNPTYNRDPKIVARARSKVAGEDIQVSAPTTAKQPANQPRQDSQRGGKQV
                     ISFR"
     gene            40289..40738
                     /locus_tag="ACZPB4_02075"
     CDS             40289..40738
                     /locus_tag="ACZPB4_02075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HIR1097043.1"
                     /translation="MDLFEQVSEDIKNAMKAKDKVALETLRNVKKFFLEAKTAPGAND
                     TLMDADALKIMQKLVKQGKDSATIYVQQGRQDLADVELEQVKVIEKYLPQQMSAEELE
                     KELKAIIAQVGAAGPKDMGKIMGVASKALAGRAEGRMISETVKRLLN"
     gene            40854..42263
                     /locus_tag="ACZPB4_02080"
     CDS             40854..42263
                     /locus_tag="ACZPB4_02080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0015833 - peptide transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation CstA family protein"
                     /protein_id="HIR1097044.1"
                     /translation="MITFTCCLIALIVGYFTYGKFVERVFGVDPSRVTPAFTKQDGVD
                     YIPLPTWKIFMIQFLNIAGLGPIFGAIMGAKFGVASFLWIVLGSIFAGATHDFLSGML
                     SLRHDGESLPELIGRYLGNNFKQFMRGFTVILMILVGAVFVAGPAGLLAKLTPEYLDA
                     TFWIIVVFIYYILATLLPVDKIIGKIYPLFAIALLFMAVGILVMLFINQPPLPEITDG
                     LSNTHPGGLPIFPIMFVSIACGAISGFHATQSPLMARCMKSEKYARPVFYGAMITEGI
                     VALIWAAAATYFFHNNGMEENNAAVVVDSITKEWLGAVGGVLAILGVIAAPITSGDTA
                     FRSARLIVADFLQMEQKTVVKRLMICIPMFIVAIGILLYSQKDKDGFDMIWRYFAWSN
                     QTLAVFTLWALTVYLVQAKKLYVITLIPALFMTAVCSTYIFVAPEGFGLSSGFSQLLG
                     LLVTLIVFGIFLVWKRKKV"
     gene            complement(42317..43048)
                     /gene="rprY"
                     /locus_tag="ACZPB4_02085"
     CDS             complement(42317..43048)
                     /gene="rprY"
                     /locus_tag="ACZPB4_02085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005634267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000976 - transcription cis-regulatory
                     region binding [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor RprY"
                     /protein_id="HIR1097045.1"
                     /translation="MEEKLKIFFCEDDENLGMLLREYLQAKGYVTDLFSDGEAGYKGF
                     TKGKYDLCVLDVMMPKKDGFTLAQEIRSINPDIPIIFLTAKTMKEDILEGFKIGADDY
                     LTKPFSMEELLLRIEAILRRVKGKKMKDIPFYKLGNFLFDTQKQTLAIGDKVTKLTTK
                     ECELLSLLCAHANEILERNYALKTIWVDDNYFNARSMDVYITKLRKLLKDDPGIEIIN
                     IHGKGYKLITPSGEEQAREEGIQVL"
     gene            complement(43051..44610)
                     /locus_tag="ACZPB4_02090"
     CDS             complement(43051..44610)
                     /locus_tag="ACZPB4_02090"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1097046.1"
                     /translation="MRKSTIWLLAVVMAFAFAGLLYLQVNYVSIILKTRSEQFNETVK
                     RSLRQVSKNLELDETRKYLEDDINRDETNFMYQNAPDAQSLGQVINHEKYQLQIKDSN
                     GTVQQIEMQSFSAHKFEPLSSLSKRQSANSIVNTSKDLQKTLKRRYQYQGGLIEEVIY
                     NILYTANLKPIEERIDFKKLNNYLKTEFINNGLNLPFVFSVINKDGNVVYQSGEFQKQ
                     PIASDVITQVLFPNDPPSKLNYLRVYFPTKGDYISSSITFIVPSVIFSLILLITFVFT
                     IYIVFRQKKLSEMKNDFINNMTHELKTPVSTISLAAQMLKDSDITKSPDVFKHISGVI
                     NDETKRLSFLVEKVLQMSLFERQKAALKLKEIDANDLVANVANTFVLKVEKYGGTMDI
                     DLQATESDIYVDEMHITNVLFNLMDNAVKYRRPEVPLTLMARTWNENGKLLISVEDNG
                     IGIKKEYLKKVFDRFFRVPTGNVHDVKGFGLGLAYVRKIIEDHKGTIRAESGAGNIGT
                     KFIITLPLIKS"
     gene            complement(44875..47694)
                     /locus_tag="ACZPB4_02095"
     CDS             complement(44875..47694)
                     /locus_tag="ACZPB4_02095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane beta-barrel protein"
                     /protein_id="HIR1097047.1"
                     /translation="MKSGKCLLMLLMILFSPMAFAQQSGVNVTGSVVEQGSDTPIEQA
                     TVRLLNVKDSAMVRGVVSARNGSFTLKNVKKGSYLLHITFIGYDPLYQPLQITGKKNP
                     VNVGKLELSDGAIELGEAVVIGKAPEVTVRNDTVEYNADSYKVTEGSVLEDLLKKMPG
                     VEVDSEGKITVNGKEVKKVMVDGKEFFSDDPKVASKNLPAKMIDKLQVLDKKSDMAQM
                     TGFDDGEEETVINLTVKPGMKQGWFGNAYGGYGSKDRYEGNAMVNRFVNNDQITFMGG
                     ANNTNNMGFSDLASTMFSGMGGGGGRRGGFGAGSGITSSGNAGLNFSKEFKPDKLTLG
                     GNTRYSHSDNDARSKSDRQNILPGDSSSYDNSEAMSRTKSDNFGVDFRLEWKPDTMTQ
                     LIFRPSFSFSHSMNDNFSDATTLDNERDTVNTNKSSNYSESNGYNLNASIDFSRKLNN
                     KGRVFSATLSGGNSDSYSDGMNRSDIVYFNQTDALKNSIIDQRSRYDNKGFNYRAYVS
                     WVEPIGHNNFIQATYSISQRKQEALKNVYNQDADGIYNVLDSAYSQSYRNNFISQRAS
                     LSFKSQRAKFNYTIGLNLDPSYSSSENFVGDTTLSKITRKVVNLSPMAQFNYMFDKRT
                     NLRIMYNGRTSQPSMTQLQPVADISDPTNITIGNPDLNPRYTNNVFIRFQQFTPEKQR
                     AFMIMANGSYIINDIVSYTSYNQETGVKTTTYKNVNGNYSGNVRMMLNTPLKNKKFSI
                     NSMTMASFANSNGYINEEKNTNRNLILSERGGIDFRSSYLDLGVNGNIRYNATSNSLQ
                     KENNQNTFNYGAGGYTTIYLPLNFKIESDVNWSTNSGYGDGFKQNEVLWNASASKSFL
                     KNNQGTLRFKIYDILQQRSNISRSVTASYIQDSEYNTLGSYFMVHFIYRFSIFKGGAS
                     ASDVKTPGRSGRGRGPMGPPPGHRF"
     gene            complement(47825..48376)
                     /locus_tag="ACZPB4_02100"
     CDS             complement(47825..48376)
                     /locus_tag="ACZPB4_02100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma-70 factor"
                     /protein_id="HIR1097048.1"
                     /translation="MDDSTLIEQIQLGSKDAFKQMFIKFYSPLCEYASQYVSDEDAEE
                     LIQELMLFIWENRNSLFVEISLKSYLFMAVKHRCLNAIKRQLYHERVHSLIYDKIKDQ
                     FENPDTYFVNELTENITKAIEELPENYRETFKLSRFGEQSNLQIAEALGVSIKTVEYR
                     ITQSLKILRVKLKDYLPFIMFLF"
     gene            48648..49706
                     /locus_tag="ACZPB4_02105"
     CDS             48648..49706
                     /locus_tag="ACZPB4_02105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecR family protein"
                     /protein_id="HIR1097049.1"
                     /translation="MKTENRHINIQEPEGMMLLRYIKDTASNEEKSYIEAWLEADENN
                     KRILLQTARIYYANNAMERIASRNPLIAYEKLEQRLAKRTRLYWLKRFSAAAACIIAI
                     IGLSTLFSHRKVDSEFGDPQIITLQANAGVRTRFNLPDGTVVYLNSGSVLSYPMSYDQ
                     KERKVCLSGEAYFKVTHNEKQPFIVSTSGDQHRVRVLGTEFNIQAYGDENIISTTLVT
                     GSVNLEVKNKSGNVSHRTLLPSEKAICNLDKEEISVMKINTIYETAWMDGKLMFKDTP
                     LPEALKKLSYYYNVEFVIQDAEIKSYCLTGILDNRLLSQTLDYLRISSNIDYRIEDMK
                     TDDSKGTNRTRVILWKGK"
     gene            49889..53149
                     /locus_tag="ACZPB4_02110"
     CDS             49889..53149
                     /locus_tag="ACZPB4_02110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SusC/RagA family TonB-linked outer membrane
                     protein"
                     /protein_id="HIR1097050.1"
                     /translation="MMNNLYFQLDGDKSAFVRLVSKISRIMKLTLFLVCLSISMSFAM
                     TTNAQSTSLSFKATDQSIKEVLELIESQTDFHFFYNSKLVDINQVISVDIKDKDVFTT
                     LDHIFKNSNIRYKIVGKDVILSVKGSKSDQDEKTVTGTVIDEAGEPIIGANIVEKGKA
                     NGTMSDLNGHFSIVVSSDAVLQISYIGFSLHEEAVKNKNVLQVIMKEDTQKLDEVVVV
                     GYGSVDKKELTSAVTAVSSKDFLQGAFTSPLSMIDGKVSGVNVSNAAAADPNSSPNIQ
                     MRGASSIEAGNSPLVIIDGMPGADLRSVANQDIESITILKDGSAAAIYGSRAANGVIL
                     VQTKKGKAGKVSISYDGYIDHDMVANQPKVLSVDEFLAHERDVDFGHRVDWYDKLLNK
                     SNLGQSHYLAVSGGSENLTFRASANYKKKDGLDIASSRKEYGVRMGFTAKTLEGLLEI
                     QGNLSTRVINEEYVDYGVFQQAVKLNPTHPLMDEKDPSKYSTLYGFDTYNPVGWLKDK
                     EDGGDRQFSLADFKMKLNILPTLNTELSLARQGQEYFKRIYVNSNHKESIDNMRSGRG
                     TLQEENYTDYTLEWIGNYFTTIDKHTIKLMAGYSYQEFNHRSFSSENANFPSDAMSYN
                     NLEAGDWNMAAGRLGVSSLKEKEKTIGFPARLIYNYDDTYYLTASVRYEGNSKFGANH
                     KWGWFPAASAAWRMSSLPAIKNIEAINDLKLRFSYGVTGRSGFPKYSALARYEQGGYW
                     LDDNGQWTQAWGPTNNPNPDLHWEKQISYNLGVDFSLLKNKLSGSLDAYVKQGKEVIS
                     NYDAPLPPFMFDQIFTNVASTSSKGLELTLNWDVVNMKDFSYSTNLVASFTKSKLDKF
                     SNGTYQKGYMDRYLLPAPGNPGYAQRLQDGVEIGSFYGLRYAGVDDNGNMLVWKDAKI
                     GGEKILANGEASDTDKDYIGHGTPRYSLSWGNTFRYKGFDLSLYFQGRFDYQILNMYQ
                     MYYGLVAEPGMNLLEDAYGKNGHIKSGKVMCDYFLEDGDYFRLDNITLGWTPKLDTKW
                     ISNLRVYATVKNAFTITKYSVMDPTSVDINGLEPGISGLNVYPIARSFTFGIQISY"
     gene            53167..54855
                     /locus_tag="ACZPB4_02115"
     CDS             53167..54855
                     /locus_tag="ACZPB4_02115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RagB/SusD family nutrient uptake outer membrane
                     protein"
                     /protein_id="HIR1097051.1"
                     /translation="MKKFKYIIVLFVMGLISFSCTDLDEEIFSEITTDNYYQNSNNIY
                     AALVNNYAKAFSTGWSDARYFLQEVTADQLMIPTRGKHGYNGGEYVRLHEHKWTVEEN
                     FVYNGWAAPFQGIALCNNTLSDFENLDFSTFKLTEETKNEYIAELRALRVWNYMFLID
                     FFRHVPIVTDIEEVKAQSTPLEVFNFMESELLAILPDLPKNRGVSRFDQAGVASILVR
                     LYLNAEKWIGISKYDECEQMAQAILDGKYGEYSIDPDYRGPFRSGINGYRSKENIMEF
                     AIKKNYFEASWLYNMWMHYQDRYSLDNDWQGWNGGNLAPSRDLYGNLYQDKLGMPFEK
                     FPDEDIRKKAFRVISNDGDYEGFFLMGTQYKFDYEKGYGFTDEVITGTEEYNGKPLVY
                     VDQVGRFSEGETGLAKGSHVIYGEENTGYRLIKFPWLPQSKDLFQMNSIPEIRLAEIY
                     YSLAECKYRSGDKIGAARLLDAVRKRYYKAEDWSKFSYESNISKLTDDEFVDELGREF
                     IGERHRRIDLIRWNRFSEGAWWDKTPDATNQDVFPIPYRALNANPLLKQTTAGF"
     gene            54872..55543
                     /locus_tag="ACZPB4_02120"
     CDS             54872..55543
                     /locus_tag="ACZPB4_02120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-disaccharide hydrolase"
                     /protein_id="HIR1097052.1"
                     /translation="MKQFINVKRVFTVLIILLLLISCRVETDYRPLFDKDLSNADYDS
                     SVWTFKNGILTATADQSIWTKVQYENFILDLEFKTDVNTNSGVVIYCTDKGNWIPSSI
                     EIQIADDHHPEWQSYPEYWRCGSIYGHKGANEQLVVKKPGEWNRMIVTAKGQQIDIEL
                     NGKHIVSANLADWTSGTTNPDGTEIPEWLPIPYANMPTKGYIGLQGKHGESNIWFRNI
                     QLKQL"
     gene            55557..57068
                     /locus_tag="ACZPB4_02125"
     CDS             55557..57068
                     /locus_tag="ACZPB4_02125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HIR1097053.1"
                     /translation="MRHISRRDFLKTGALAAGLTIVPNSVLGKTHGFTSPSDKLNIAG
                     VGVGGMGRGNLRNMSTENIVALCDVDWRYAEKTFNDYPKAKKFKDWRVMFDEFGKSID
                     AILVATPDHTHAGVTAHAITLGKHCYTQKPLTHSVYESRLLAKLAKKYKVATQMGNQG
                     NSFDWCRQITEWIQSGVIGEVYEVHCWTDRPIWPQGLMQPSDNLKCPKTLDWDLFIGP
                     AQKRPYNPVYTPWNWRGWWDFGTGALGDMACHIMDPLYWALDLKYPISVIGSSTLSNL
                     YSPPHAQVVTYTFPARPPKGNTKMPEVKVYWYDGGLMPPRPEELKDGQMMGDENGGII
                     FIGTKGKIMTGCYGMNPTLLPVSDMEHFNQPKPSIPRVKGGNGNIWATNAHEQDWIRA
                     CKESPENRVESSSNFQFSGPFNEMVVMGVLAVRLSGLHGLHRELLWDGENMKFTNISP
                     TDTIKIVTVDDFKVVDGDPRFDRRFADFNALDVANEWIKHTYNNGFSLPSMPF"
     gene            57214..57786
                     /locus_tag="ACZPB4_02130"
     CDS             57214..57786
                     /locus_tag="ACZPB4_02130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HIR1097054.1"
                     /translation="MDVERIYLERLRSGSYRDFTKLYESYASRLYAFALHLTHSDALA
                     KDIVQETFIKVWVRREQIDLDMSFSAFLFTMAKNQLLNEFRRQANSPLFLEDVVLNES
                     GDGEETAIERKLSFEEFNHRLEIAKQKLTPRQRELFELNKEQGITITEIAAKAFISEQ
                     SVRNQLSQALHVLRKELGKYALLFSLFFIG"
     gene            57856..58866
                     /locus_tag="ACZPB4_02135"
     CDS             57856..58866
                     /locus_tag="ACZPB4_02135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecR family protein"
                     /protein_id="HIR1097055.1"
                     /translation="MCIPYKKGIMQESHTYYLLSKYMDHTISTEELKTLRLLVNLSDD
                     DELSLSLSLLWENGRPFEEVDERIIRDMFSGIQNRTRKERFVMVFRKLARIAAILLIP
                     LLSVLSGYLYFNPVNQEEGIGNLVVHADRGERSGVTLPDGTQVKLNAESSLSYTHDFG
                     RELRQVNLEGEAYFEVTRNEDKPFVVHTKYLDIEVLGTSFNVYSYERENVMEMALISG
                     RIKIQTCSEPSRVVYLKPNEKALFNKESGIITVEKTDNRFETAWLRGDLVFRSTTLSD
                     VLAKLERRYGVNIHLNDSSLANDLFTGNFDSEYIVEVMDLLERHYDFTYDVRGDDIFI
                     HP"
     gene            59083..62325
                     /locus_tag="ACZPB4_02140"
     CDS             59083..62325
                     /locus_tag="ACZPB4_02140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HIR1097056.1"
                     /translation="MALFLFFNPILVLAQTGSVTLSMKNATLKQFFEAVEKQTTYIFS
                     YRDAIVEGKKEVTLNVTNQPIQRLLDDVLHQRDLQYTMTGHSIVVTLKTAGKVKQVSG
                     TVVDSNGEPIIGANVVEKGTTNGTVTDISGNFSLNIDDTGILQISYIGFNTQDVAVNG
                     KSSLMINLKEDTQKLDEVVVVGYGVQKKSNVTGSVASIKTDDFNDLNMDVSHVIQGRV
                     AGVNVSNGNIIIRGAASINGADPLWIVDGVPGSAPNFNDIESIEILKDAASTAIYGAR
                     GAGGVILVTTKKGKIGKLSINARVNFGIETPIDLPDMLHTADFIDRKLAAGFPNNPNS
                     GWDNPASLPDTDWEDLVWRNAFRQNYFLQMTGGNEKTTFNMSAEFYKNQFIERYSFED
                     AGNFRVASQTNISKRVKFSEILTVGFNNTDPHLYGQTNNDYVYYRQVPTMVPYDNTNE
                     AGGGWGKHPAGGYYEGPNHVATLMSHHANERRFWARANAILDWEIINDLKFQANFSAN
                     FDSHANNLFLESWNLGSLSQQDYYSKDYGSGYDLRMLYTLTYDHTFGEKHYVKGMVGY
                     EAYRATASSAGGWKNGFLVQPSDDISLGTGDKDVSGTKTEGRSLSQFARVNYAYDDRY
                     LLEASIRRDGYDNFGPENRFGVFPSASVGWNVGKESFVKDNITWMSQLKLRGSYGKIG
                     NNTIPQFLYEPSFTNNYLYYSYDGQNTQRGFWYSNVANATIKWEDVAQWNIGVDASFL
                     DNRLNTTIEYYDKKTSDMLYSVGVPPSAGPSSEPFSETSSYRANIGKISNRGFEWMVQ
                     WRDSYKDFRYDVAFTLSTNKNKVVKLSDQVNPIIWAGSDAALNSSIYRTENGQPMGQM
                     YGYVVDGIIQDQAEIDALNAQSPDGLYQQAGTAPGDLKYKDLNGDGKVTNEDKTYIGN
                     PWPDLMYGLNINLSWKGFDLSMGWLGNAGVDVFNSAKLYERSFYGDYNTTYKVYEAWS
                     PTNRATSHPRVTKEDPNGNFKNVSSYFVEDGSFFKLKNLHFGYNLPKSILSHLKIEGL
                     KFYINCDNLFIITKFQGDPELGGGYLERNMYSVKRAPSTRTIMGGLSLTL"
     gene            62338..63927
                     /locus_tag="ACZPB4_02145"
     CDS             62338..63927
                     /locus_tag="ACZPB4_02145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:2001070 - starch binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RagB/SusD family nutrient uptake outer membrane
                     protein"
                     /protein_id="HIR1097057.1"
                     /translation="MKKLVILLAAALTFNSCSDSFLDLSNPSALSPSVYPKSMADMET
                     IVTSVYANMVAVPLYGKRVMAKGTFCVDHTVDMAWTGDANWNQLATNQVTSDNAYIGT
                     LWIGYYKMISCANTVLEQLERIDKEKFTDADLARLSQMKGEALFWRGWAHQQLVAFFG
                     EGYPCNGDGDKKGVPVRLQVASTPDMLNIERSTVAEVYDQILKDYEAAKLLLPAVWEE
                     RADYPRPTSVAVASYIGQANLYMGNYDAAKKALKEVIDSSGKELLPFNEYAKMFNEDQ
                     EKFNRESILEINFRNGDTSGYFWYGEGSQYGLIAALCFQNASGDVEAAGWGNIFFHDA
                     NIKRFNGDPRLDIAALRPGTPVIMNGQQTQVLKYKDTEADIQGWSMRKYNPLKSTVNE
                     LNLGVGINMYLMRLADVYLMYAEACQATGDEVNARNYMNLVRRRAYNGDSSHDITASG
                     EALRDAIREERFMEFCGEGVQHWQDVCRWKVLDEEISRWYGKTRVGNPHYDAKDLYFP
                     IPKVEMENNPNMTQSIGYENE"
     gene            64039..65379
                     /locus_tag="ACZPB4_02150"
     CDS             64039..65379
                     /locus_tag="ACZPB4_02150"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HIR1097058.1"
                     /translation="MKMIDVSKVRVFRGSLFVLLMLFMQIGWASNDDSTYNIVDFGAK
                     GDGITDNTQFINRTIEACSLRGGGTVIIPEGTFLTGSILLKSKVNLFLESNAVVKGIN
                     NLEKYRSISDLNQDEAYYKVKPRNWNKALLLGDQVEGVSITGEGVIDGAHIQDKKGEE
                     GMRGPHILFLSRSKGIKISGVKLRRASNYAFMSYDIERASFDNLLVEEGWDGIHIRGG
                     KDIRIRNCRFYTGDDAVAGGLWKNMVIENCYMNSSCNGIRLIMPATGLKIVDCEFRGP
                     GKYPHRTSGEQKRRNMLSGILLQPGAWFPAFGEVKDILISSCSFDQLDNPFLVTLNEG
                     NRGERICLEHIRGTRLMKAAASVESWGDSSLKDVRLSDVSLSYVGNKDQEIVGRTPSK
                     PLTDYRALPCWGLYLHNLDRVILRNVRLDCENGKVGPASCFDNVGSVEIYNVSF"
     gene            65397..66812
                     /locus_tag="ACZPB4_02155"
     CDS             65397..66812
                     /locus_tag="ACZPB4_02155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 140 protein"
                     /protein_id="HIR1097059.1"
                     /translation="MRKYLLFCLAFCVLGCLAQDLIVRPNDPIIYKKEGGAFLWLGDT
                     AWELFHVLDKEEIVHYLDNRQEKGFTVIQAVILSELDGLDKPNAYGYLPLVDKDPTQI
                     TEGYFELVDFVIREAGKRGMYIGLLPTWANNVVEKDGNPALFNPDNAYTYGKILGTRY
                     KNEAVIWILGGDRNVVTDKEFEIWQSMAKGIQEGNGGTQLMSYHPTGEISSHYWFHNE
                     SWLSFNILQSGHYRRMDPVYRFSGMYAQLNPIKPFVNAEPSYEDIPVLFWEYFDYAKF
                     GKKKEDIIGDNGLIKDTTYFTDGIYDDYDIRMQAYWTYFSGAAGYTYGNNAIWQMYKP
                     GGKYHVPCLTFWDGALDRPGAECMRYVKSLFTMYPLDRFRPDLSVLFGINYNDASYIT
                     PVLAKDKTFILVYLSQGQDVRIQMSKLRSLGKAYWFNPRNGARTLIGPVENKGIRTFN
                     APGEAGERGNDWILILEADDR"
     gene            66846..68024
                     /locus_tag="ACZPB4_02160"
     CDS             66846..68024
                     /locus_tag="ACZPB4_02160"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 172 protein"
                     /protein_id="HIR1097060.1"
                     /translation="MKKINVLLLAFLLLSFWANAQQYPFNGLDMNMGNLSRLSNAQSR
                     SISPENFTGEKGKGAMADPVRDKDVRNKANAAGPAKDLGKGWKVNPFIIVKPGETVTI
                     AEIDGPGAIQQIWMTPTGNWRFSILRMYWDDEKEPSVECPVGDFFASAFNEYAQLSSL
                     AVCVNPGSAFNCYWKMPFRKKARITLENINNAEEMRLYYQINYTLTEVPEDEGYFHAQ
                     FRRSNPTQGSSHTLVDGIKGKGQYVGTYLAWRVNDNCWWGEGEIKFYMDGDKEYPTIC
                     GTGTEDYFCGSYNFENQKTHQYQEFTTPYAGMHQVIRPDGLYRAVTAFGLYRWHILDP
                     VRFEKDLKVTIQDLGWRHDGRYNNQKSDISSTTFWYQAEPHAKFPALPSKDDLEIPRW
                     "
     gene            68146..68529
                     /locus_tag="ACZPB4_02165"
     CDS             68146..68529
                     /locus_tag="ACZPB4_02165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097061.1"
                     /translation="MKKVIGLCLVVLLSSTSVFARENRRMDKRKMDPSARCEKMIADL
                     KLDEKQAVEFRKLQKEYMEKAQKEREAMKAEREKQREKMLAMREDKNAQMKKILTEEQ
                     YKQYLEKQQPKGNKHGRKHLGNGRR"
     gene            complement(68587..71403)
                     /locus_tag="ACZPB4_02170"
     CDS             complement(68587..71403)
                     /locus_tag="ACZPB4_02170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NPCBM/NEW2 domain-containing protein"
                     /protein_id="HIR1097062.1"
                     /translation="MNKLIFTAILSGFAGLYAMGQNEIRLMDMDLNKSYQTYGGAVKG
                     KSVTNEPASIQGKTYDDVIGVQAKSHIKIDLHKNASRFQAQVGIADSHIDYTDKSLTV
                     IPFVDGTKMYFDTRKNAKTFVGLEGKDGKVHPGSVLFILKGDDKELYNSGIVKLGDAP
                     KTIDIPLNGIKILDLIVEPTDDGPSGDHALWITPQIEYMEIIPSIISTSYQGKGPEVS
                     SGTEKKLLDKIKRLPQQGLPLENTSFDWLLQPSRSKAGIYATPDGKSILLSNGMVARM
                     FRVLPNLSTLDIFNRMTGESMLRAVSSEGSLTIDGKRWELGGLAGQPERGYFQMEWVE
                     QMTTRSGSFLIEDFRIEELQEDIKWARSRWALNKNVPTGKRLTFVLKGEKETEGVTVE
                     LHYDLYDHIPVIRKSMEVTNKTPQSIDIDAFQLEYLAFAEPESPGGGDPSKFRLPNIH
                     IESDYACGGEFTERETDITEKWVADPEYTSQRNYPLLTPCILDVSPKLGPDYTLAAGQ
                     EFKSFSVYEMPFDSDDRERKGLFKRRFHYTVAPWATENPIFMHLTSSDPDVIRTAIDQ
                     CATVGYEMVIISFGSGLNAEDISEENIAKYKSLVDYARGKGVELGCYSLLSSRWISDE
                     VDVINPKTGKRGGMRFGSAPCLCSDWGYEYFHHIRTFFERTGMRCFEHDGSYPGDVCA
                     STHHTYHKGLEDSQWNQFHKITDLYRWMCENGIYINVPDFYFLNGSTKTGIGYREANW
                     SLPRDRQIIHARQLNYDGTWDRMASACWSFVPLVEYQGGGEAATLEPLHEHLFEYKTH
                     MMQNYGAGVQACYRGPRLYDTPETQAAVTEVIQWYKKYRDILNSDMIHLRRPDARDWD
                     GFIHVNPHKKEKGLAMFFNPTHQEITRTIHIPLYYTGLTQTARIREKEQKPVTYKLNR
                     DYTVELTVKIPANGYTWYVVEAAD"
     gene            complement(71508..72800)
                     /locus_tag="ACZPB4_02175"
     CDS             complement(71508..72800)
                     /locus_tag="ACZPB4_02175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-disaccharide hydrolase"
                     /protein_id="HIR1097063.1"
                     /translation="MESVMKKTAATSLLASCAVSLALFSSCASQEQNTLTPEEIADGW
                     VLLFDGKTLDGWKDYNGTTLTQPWHVVDGCIQAKGDGSDASGYIVTDKEYENFELSWD
                     WKLSKGGNSGMLYHVVERPQYAVPYVTGPEYQLIDEPNFPEPLEEWQKLGVDYAMHLP
                     DKSKMKVNPQGEWNNSKIVFDNGHVEHWLNGQKIVEFEAWTDDWHAKKNSGKWANAPE
                     YGLAKKGVLCLQDHGYPASFRNLKIKELPRKTGKEVNLFNGVDLTGWEPYGTEKWYVK
                     DGLLVCESGPDKQYGYLATRDYYDDFDLTVEFKQEADGNSGVFIRSFVEEGVKVNGWQ
                     VEVAPKGHDTGGIYESYGRGWLVQIPDEKENILKEGDWNTMRIKVQGDNVQTWLNGQE
                     MVNLNDEKIGAGKGRIALQIHDGGGIKVLWRNLKLTTL"
BASE COUNT        19806 a        13961 c        18303 g        21290 t
ORIGIN      
        1 gataaaaagg aatgtctatc tttgttcatg gtaagtatat ctaaacgatc atcgctatga
       61 accagacaat ttatcctatc ggcatacaga acttcgagaa gatccgtaaa gacggttatc
      121 tctatattga taagacagct ttgatttatc agttggctaa gaccggaagt tactatttct
      181 tgagtcgtcc gcggcgtttc ggcaagagtc tcttgctatc tacgttggag gcctatttcc
      241 aagggaagag ggagctgttc gaggggttgg cgatggaacg gttggagaaa gactgggagg
      301 tatatccgat cttgcatttg gacttgaatg ctcgtcatta taaagatact gccgctctga
      361 ctagtatctt gaatgagttc ttggagaaat gggaggcttt atatggaacg gagaaacagg
      421 atcgtgcctt ggaggaacgt ttcagttatg tgatagaaca ggcttaccgc cagaccgggc
      481 atcgcgtggt gatattgatt gacgagtacg acaagccttt gctgcaaaac ctgcacgatg
      541 aaaagacgca aacgcaattg cggaatatgt tgaagccttt ctacggcgtg ttaaagacga
      601 tggatagagc cattcgtttc gctttgttga caggggtgac gaagtttggt aaggtaagcg
      661 tgttcagcga tttgaataac cttatggata tctcgatgga caatcgctac gtcgagatat
      721 gtggcatcac ggagaaagag atacatgcct acctagaaga ggagttgaag gagctggctg
      781 agacacagga actggattat gaggaaacca gccagaaact caaggagcgc tatgacggat
      841 accattttac cgccaagtct gcgggaatat acaatccctt tagcctattg aataccttcg
      901 ccaagatgga gttcggagat tattggttcg agaccggtac gccctcttac ctcgttgaat
      961 tactcaagca tacccattac gacctttacg agatggcgaa cacggagact gatgcggatg
     1021 tgttgaacag tatcgatgct gcctcgaaaa atcccgttcc cgtaatctac cagagtggtt
     1081 acttgacgat caaggattac gatcctgaat ttggtatcta ccggctaggt ttcccgaacc
     1141 gggaagtgga agagggtttc gtgaaatatc tccttccatt ttacacgagt gttagtgccc
     1201 ccaagacccc tttcgagatc gggcaattcg tacgagagat acgctccggt gattacgatg
     1261 cgttcttccg ccgtttacaa agcttcttcg ctgatacacc ctatgaggtg atcgccggcc
     1321 agaagccgga gcgtgatacg gagttgcatt accggaacgt gctttttatc gtatttaagt
     1381 tggttggact ttatacgcag gtggaatatc atacctcaca agggcgtatt gatctcgttc
     1441 tgaagaccga tcgctatatc tacgtgatgg aattcaagct gaacggcacc gccgaggagg
     1501 cgttgcgcca gatagaggag agacagtatg cgcttccctt tgcgagtgat ccacggcaag
     1561 tttttaagat cggcgtgaac ttctcctctg tgacccgtaa catcgagcga tggttggtgg
     1621 aataataatc tattaagtat atgaactgga aacaaacgct tttctggtct ttttcgacag
     1681 ctgctatttt ttattatttc ctgctttttg gcgtgtttgt gtttgtcggt caggaggaga
     1741 tgcaattgtt tatacctgag tggtggtata tccgggagtt cctttttcag ccgggaggat
     1801 tttgcgctgt cgccgggcaa tggatccttc aatactaccg gcagcctatg tcggcggtgg
     1861 ttctccatac ggttttactc gttggttgcg ggtttatggt ctataggatc ttgcgttgtt
     1921 tttctgacaa gacctacctg ctgttccttt ctttattgcc ggtcctgtat ctggttaaga
     1981 tgagtattca tggggagtat ttggtggacg ggacggttgg cgtggttttg atgcttttag
     2041 ctttgtcggt ctcgctaaag gtgcggcggg cgggttctat tgccggatac ggaattgcct
     2101 ctacactttt tttatgtggg ctgaccgggc ttctttcggt ctgttacgct ttcttatata
     2161 cgctgttagc cttactccgc tacaaaacgt cgcggcaaag attggccgcc gctgcctgct
     2221 tgatcccagc gctttttatc tatttgttta gcggatggtt agggattcct gtacctttgt
     2281 ctgatggatg gatgccggaa gcctatctgg agatacagcg attacctcat tattatatgt
     2341 atcgtgtatg gactttcttt accctttcga ttgtcggtgt tgctttattt gctcgctttg
     2401 ttccggtgat tggcgagaag agtaaatgga tggatcgggt agcccttgtt gtttgtctga
     2461 tcacggcgct ggtatccatc cggttttgcc tgccggaacc ttggcatgcg caacgcatga
     2521 tgcttgacga gctctctttc ttagcccggg agaggcaatg ggacgccatt attgataagt
     2581 accggggaaa gcagatctat aattatgtta gcttaaacta tttgaatatg tcgttggccc
     2641 ataagggaga attggccgac cggatgttta ctttcgatca gaaaggaacg aaaagcttat
     2701 gtgccgattg gaatcagacc ttttacatgg atcgtttatt gagcgatgtt cattttcttg
     2761 ttggcgatgt ctctttgtct gaaagctttg cgatggacgg atttacgcaa gccaaacgta
     2821 aagggagtgc ccgcatgatg caacgtttcg tgcaagtttg tctgattagg ggtgaggtgg
     2881 cgctggccaa gaaatatttg gacttgcttg ccgctatgcc attctataaa gattgggctt
     2941 gccgttatgc tatctatctg gtacatccgg aattaatgga taaagatccg gagttgagtg
     3001 acaaatatat gcctgttgag aaaagagatc gactgagttt gtccgtacct gtcgattcct
     3061 tatggagtgg atacaatctt ccggatcatc ggatcggttg ggaataccgg ggatgttatt
     3121 atttgttggg taagaagctg gatgcatttg gccgattctt ggaagagaca cctttcatga
     3181 agggggaacc gataccccgg catttccaag aagccggatt gttgttggcg gacaaagaca
     3241 gtatatcgct ttcctcctat tccatacagc cggagatcgt agatcgatac cgggaattca
     3301 agcaggtttt gggacgatct gccaaccaag tggatgtgtc ctcgatgtat cgacaatttg
     3361 gagataccta ttggtattat tactatttca agatctttaa aggagaagaa taatgaagcg
     3421 attatctatc tgttggatta taggttgtct tttgggactt gtggcttgta gaccggaagt
     3481 tcctgcgcaa gcggaacaag gagaaactga cgtgtttccg gattacaggg aagttactgt
     3541 accggtcaat atggcccctc ccaatttcaa gttggttaat caacagctac aggggataac
     3601 tcggttgaaa actatgaata gggagttgat aatcgcagcc gatcatggtg ttttcaacct
     3661 gccggaaacg gattggaagg tcttatcgca ggacgcacaa ggaaaacaaa tagatgtgac
     3721 ggtttatttt cgagaacctc aaagtgattg gaaacaaatg agtttcccta tctatgtgtc
     3781 aagagattcc gttgacgctt atttggtgta tcgccgtatt tttcccggat atcggatgtg
     3841 gaacgagatg gggatttata aacgatgtgt tgaaaactat gttgaaaagt ctattcttga
     3901 taaccaatcg acaaataata gttgtatgaa ctgccatgcc ttttgtgagc gacaagggga
     3961 acaaatgctt tttcatcagc ggggttctca taatgggact tacttgattg atcatcggca
     4021 ggtaaagaag attgcgttgg aacgggacgg taagccggct tcgttcgttt atccgtattg
     4081 gcatccatcc ggccggtatg tcgctttttc taccaatgag acccaccaag acttccatct
     4141 ttccgatgag aatcggattg aggtatatga cgtggaatcg gacgtgctga tctatgacac
     4201 ggagaaggag agggtattca gttcgccatt attggcttcc atggcgtgtt atgagacttt
     4261 tcccactttt actccggatg gtaactatct gctgttctgt tcggcggatt ctgtctgtat
     4321 gccggaaaat tatcgggatg tccggtataa cctgctacga gtcgcttttg atccggaaga
     4381 cggttcgatt ggaacccaag tggatacctt atataatgcg agggaagcgg gccggagtgt
     4441 taagttcccg agagtctccc cggatgggaa gcggctactt tatacggtgt ccgattatgg
     4501 caatttctct atttggcata aggatgcgga tttgtatatg ctggatctgt ctaccggggc
     4561 aatcgattct ttgccggaag tgaatagccc ggatgtagag agctatcatt cttggagcgg
     4621 caatagtcgt tggtttgtct tttccagccg ccgggacgat gggcttttca cacgcccgta
     4681 tttggtacat gtgaatgagc gggggcagtg cggtaaacct ttcttgttac cgcaagcgtc
     4741 tccggattat tatgaatgct ccctgttctc gtttaatgtt ccggaattta tacatactcc
     4801 ggttataatc tcgaaggaaa ggctggtcga ggcttcacga aaagaagaca ctacgaccat
     4861 taaacatatc gagggcatct aatttttcac ttctttgtgc cgaaggtatt tataaaagtc
     4921 gtacttttgc gctaaaatca aaacgatgcg aaaagttcat ttgatctccg taaccgaacc
     4981 tttggtttta gatctagccc tagcacttcg agaaaaagga tatgaggtaa gcgcttccgg
     5041 ttgtggtctg actgaagaga tgataggaag acttcataac gcgggctgta cctgttatgg
     5101 ggatgggtgg tttccggaga aattaataaa agatattcac tcggtggttt tgggtgctaa
     5161 agtaaagcaa gataacccgg aattattgcg tgcgaaggaa ttggggatgt taatccaatc
     5221 cattccggaa tttatatttc aacggactcg gtcgaaaact cgggttgttg tggcgggtag
     5281 tcgtggaaag aagacaatta tttccatgat ggtctgtgcg ttgcgtcggc aaaagttggc
     5341 gttcgactat gcgttgacta gcaaggtgga ctcgcttccg aatcgggtac atttgagtta
     5401 tgaggcacgt atcgctttga tcgaaggaga tgagcatatc acctctgcct tggacaagcg
     5461 tttccaattg gaattctatc gtccgcatat cgccatcctg acgaatttat cttggtctac
     5521 cgagacggat catgcgactc cggaggccta tttatccact tatcagtctt tctccgtttc
     5581 tattgagcgg gaagggaaat tgatttattt tggaggtgat gatactgtca gtcagttggc
     5641 aggggacgtc cggagcgata tcaccgctat cccttttgag gaacatccgg tcgtggagaa
     5701 agacgggcag acttttttgc atactcgcta cggagactat ccggtacgga ttcccaatcg
     5761 ctatttcttg atcaatctga atgctgcacg tttggcttgc cggcagttag gcgttaaaga
     5821 cgcggatttt tatcaagcgt tatcggaata tagtttatct ttgccgatat gataatagct
     5881 agacaaaaaa gaaaagagaa tatcgctgaa tatctgcttt atatgtggca ggttgaggac
     5941 ttgatccggg cgaataagtt cgatatggat tcgatcaacc gcacggtgat cgcccattac
     6001 gaccagcccg aggaggtgaa gaaggaaatc gctcaatggt acgaggaatt gatcgagatg
     6061 atgcgtagcg aaggggtgat ggagaaaggt catatccaat tgaacaagaa tgtgattatt
     6121 actttgaccg atttgcatct ccgtcttttg aaatctccga aagagatggt ttatagcgcg
     6181 gcttattata agacgcttcc ttatatcgta cagctccggg ctaaatcggg tggagaggat
     6241 ctgccggagt tggaaacttg tttcgccgcc gtatatggct atctgctttt gcgtatgcaa
     6301 gggaaagagg tgagtgcgga gacgttagag ggtattaaac aaatcagctc cttcttggcg
     6361 ttgctcgccg agaaatatcg ggaagatatg aaaggggaac ttaaactaga ggattaataa
     6421 tagatataga catgaagaca gttttggtaa ccggagcgaa cggtcaattg ggaagttcta
     6481 tccacgctcg tatcagccag tatcccggct ataattttct ttttacggat atagatacgt
     6541 tggatatttg cgacaaggag gccgtccgga aatatgtctt ggaaaatgat gttcaatatg
     6601 tcatgaattg cgccgcttat acggcggtgg ataaagcgga ggagcatgag gatttgtgta
     6661 tgcgcatcaa ccgggatgcg gtacggaact taggtgaggc cgctcatgcc gtaggtgcga
     6721 aggtgattca tgtatctacc gattatgtgt tcgatggaac gagttgccgt ccttatctgg
     6781 aaagcgatgc gacttgtcct gtttccgtat atggacgtac gaaactggcg ggagagcagg
     6841 ccttgatgga ggtgtgtccg gattctgtga ttatccgtac ggcttggttg tattccgagt
     6901 atggaaacaa ttttatgaag acggtattgc gtttgggaaa ggagcgggat gagttgcgtt
     6961 tcatattcga ccaagtgggt acgcctactt atgccggaga tttagcggtc gctatgctta
     7021 ccgtgctgga acgtgccgag gcgggtaaat ttataccggg tatctatcat ttctcggacg
     7081 agggagtgtg tagctggtat gattttacgg taaagatctt gcaaatagca ggtatgaata
     7141 accgggtgat acccatagag accaaggatt atccgacacc ggccagccgg ccgcattata
     7201 gcgtattgaa taaaggtaag ataaaaagca cgtacggact gacgattccc cattgggaga
     7261 ctagcttggc ctactgcatg aataacaaag tgtaactgat aacaatatat acatataaaa
     7321 tagaatgagc cagtattcag aagagattga aagaagaaga acgtttgcca taatcagcca
     7381 cccggatgcc ggtaagacta cgcttaccga gaaattattg ttatttggtg gcgctatcca
     7441 tgtagcggga gcggtgaagt ctaataaaat caagaagact gccacgtccg actggatgga
     7501 gattgagaag caacgcggta tctccgtagc tacctccgta atggcttttg attattccga
     7561 tcataagatt aatatcttgg atacaccggg ccaccaagat ttcgccgagg atacgttccg
     7621 taccttgacg gcggtggata gcgttattat cgtgatcgat atcgccaagg gagtagaggc
     7681 gcagactcgt aagttgatgg aggtttgccg tatgcgtaag actccggtga tcgtttttgt
     7741 caacaagatg gaccgtgatg gtaaagatcc ttttgatttg ctggatgaga tagaagaaga
     7801 attacagata aaggtacgcc cattgagttg gccgatcgat atgggacaac gtttccgggg
     7861 cgtatacaat attttcgagc agaaactgaa cctatatacc ccgagtaagc aatatgtgac
     7921 ggagaatgtg gaattcaagg atatcacgag tccggatctt gagacttata ttgatcctac
     7981 gcaagccgcg aagcttcgtg aggatataga gttgatagag ggggtttatc ccgaatttga
     8041 tgtgaatacg tatttggatg gggatatcgc tccggtattc tttggctccg ctctgaataa
     8101 cttcggtgtg aaagagctat tggattgctt tatccgtatc gctccctcgc cacgtccgat
     8161 ccatgcggta gagcgtgtgg tagacccgaa cgaggataat ttcaccggct ttattttcaa
     8221 gatccatgcg aatatggacc cgaaccatcg cagttgtatc gctttcgtaa agatttgttc
     8281 cggtcgtttt gagcgtaacg cgaactataa gcatgtacgc ttcggtaaga tgatgcgttt
     8341 cagtagccca acggctttca tggctcagaa gaaagaagtg gtggatgagg cgtttgccgg
     8401 ggatattatc ggtttgccgg ataccgggaa ctttaagata ggggatacgt tgacttccgg
     8461 agaggaattg catttcaagg gattgccgag cttctcgccc gagatgttca aatatataga
     8521 gaacgcagat ccgatgaagg caaagcaatt gaacaagggt atcgaacaat tgatggacga
     8581 gggtgtcgcc cagttgttta ccaatcaatt caatggccgg aagattatcg gtacggtggg
     8641 acaattgcag tttgaggtta ttcaataccg cctgttgcat gagtatgccg ctcaatgtaa
     8701 atgggagccg atcagcctat acaaggcttg ctggatcgag agtgataaca aacaggcatt
     8761 ggaaaatttc aagaaacgta aggcgcaata tatggcgttg gataaggaag gccgtgatgt
     8821 ttatttagcg gattccagct atgtattgat gatggcccaa caggattttc cggatattaa
     8881 gttccatttt acatcagagt tctaatatga aaagtcaatt ctccattctt tgtttacttg
     8941 ttaatctctt gttgataagt tgtgaacagg ctccccaata ctatgaggta tccggaaggc
     9001 ttcatacacc ttatcatatt aagtttgagc atactaaacc attggataag gagattgacg
     9061 agcagttgaa atatttctac cacctgttta atgcttttga ttctacttcg gtaatcagtc
     9121 aggtaaacca gaaccgtgac atacgggtag atacgctctt ccaaaaagtc tttaagaagg
     9181 cgcttgaagt gtctgctgag acaaatgggg cctacgacgt gacttgcgcc ccgttgatca
     9241 acctttgggg gtttggcttc agccggaagg atagcgtaac ccctgcccat atcgacagag
     9301 tccgtcagtt tatcggtttt cagaaagtgc gtttagaagg ggatcgcatc gtgaaggacg
     9361 atcctcgctt aatgatgaac ttttcttctt tggcggatgg aacggtttgc gatatgatag
     9421 cccaaatgct ggagaagaaa ggggtccgta attatttggt ggagtttggt ggcgagatgc
     9481 gtgtgaaagg cgtgaatccc tcgggcatgg attggcgctt agggatcacg aagcctacgg
     9541 atgacgctgc cggcatgaat caagaactcg agcagatcgt tagcttccct aaaccgttag
     9601 gaatggctac atcaggtaat taccgtaatt tttatataaa ggatggacgt aaatacgccc
     9661 atacgatcga ccctcgtgaa ggttgccctg tacagcggga tatccttagc gctacgatcg
     9721 tcgctccgga tgccatgacc gctgatgcgt atgctaccgc gtttatggtc ttaggctcgg
     9781 aggaggctaa gtccttatgc gctaaagtgc cgggtcttga atattttatt atttgttccg
     9841 attcgatagg agacgggtat catccggaat actctgaggg ctttcgccga tatctggtga
     9901 ctgccgataa ataatcgatt tatttataag ctgttaagat gttgttctta gaataggcat
     9961 tgtaagatct ttatgatgcc cattctaagg agcttataat gcccatcgta agcatgctat
    10021 aatgggcatt gtaagaaagg tctgtttata ggatggattt gatctcttcc agagagcgga
    10081 ctgtatgggt cggggtgaat ccatcggcag gtaatccttc cggattcaac catatctggt
    10141 cgatcttgga ttggtaagcc ccaatgatat cagcttccca gctatccccg atcattaagc
    10201 tctcggaccg gcgtgagttc gtgttcttta aggcgaagtc gaaaatacct ttatggggtt
    10261 tttgtatatt agcgtcctcg gacaggatca tccgttcgaa ataaggggcc aagcctgcgt
    10321 tgctaagttt cttgaattgt acctcacgga atccattgga taaaataaat aaccgatagg
    10381 aagggcggag atattccagt aattcaatgg ctccgggcac taatcgggtt ttggtggtcg
    10441 tgcgttgcaa gaaatcatta tttaccgata agacggtttt cttatcctct attcctaacg
    10501 gacgaagtac gtagagaaat cgatccaaga ttaaggtttg ccggtctatt tcccccgaac
    10561 ggtatttggc ccataagtct agattatgag gcatataaat atcaaagaaa gcctcgaagg
    10621 aggcataata ccgattaaag tggtaatcgg tatatagctc ttcaaggcat tctttattgt
    10681 tatggtacgt atcccaaagg gtatcgtcca aatcgataaa tatactttta taaatcatta
    10741 tccaacttcg atcactaaat acttgcctag gctccagaaa gccttctcgt catttatttt
    10801 caaggtcaag tttccgtctt catcctctac gaactcataa gatccttccg gatgattgga
    10861 ttttagttta gccttgcttg cgaacaaagg aatttctttt acctcacgga tatcgataga
    10921 gatgaaataa tccttgttga aaccactctg caatacttta gatttagaga acaggccacc
    10981 accggataag atcttctgtt ccttcaattc cttggaagta ccgaaacagt agtaagccgt
    11041 gtgaagggct ttatcttgag cgttcaattt ctcggattga gcggctgcgg tagtagccag
    11101 actttccaca tcctcattca aggaacttac catctcgtcc aattcttgga tacgtacgtt
    11161 cttctttgcc aaatcctctt gcaaagcgac aatcatcgtt gccttttgat ccagctcgga
    11221 ggaaagacga tcgatcgtct ttcgtaatgc ggaagattga ataccgcttt tcttcaattt
    11281 ctcctccaac tggctgattt gctccttgtt cttcttcaag gtctcgctga tcaattgcat
    11341 gttctgcttg atttgatctc tgcgtgactg atttagctca ccgccggttt gttgttggat
    11401 tgtcaaataa ttctcggcat cacgtataga ttgaaaatca gattcaatat catttagggt
    11461 ggagagcata tcattaagct catccgtgtt cttcgtattc tcgatacgta gagaatcgtt
    11521 ctcagccttt agtttcttgt aatccgctga attttggcca caagaggcca gcatggctgt
    11581 gcagacacat actaataata ctttcttcat gttctttttg cttgttaagt taaacatctt
    11641 tttctgtctc tttgtccttt ttatctttta agcctgctaa tacaataaca atctcacccc
    11701 ttggttcgtt cacggtaaaa tgctgaatta cttcttctaa ggagcctcgt acggtttcct
    11761 cgtgtaattt ggagatttcc cgggatactg atacttggcg gtccgtaccg aaaaactcgg
    11821 cgaattgcgt caaggtcttg agcagacgga aaggtgattc ataaaaaata atagtccggt
    11881 attccaaagc caattctttt agccgggttt gccttccttt cttttgaggg agaaacccct
    11941 cgaaacagaa cttctcattg ggtaatccgg atgctaccaa ggcgggcacg aaagccgtag
    12001 ctccgggcag gcactctacg tctacccctt ggcgaacaca ttccctcacc aacatgaatc
    12061 ccggatcgga gatggctggc gtaccagcat cggaaacaag ggcgatattt tcgcctccct
    12121 tgatgcgggc cgcgatttgc tccaccgtct tatgttcatt gaacttgtgg tgggactgca
    12181 tcttgttctg tatctcgaaa tgtttcagca agatgccggt cgtacgggta tcctccgcta
    12241 aaataagatc agcttctttt agcacacgga tcgcccggaa tgtcatatct tccaagttac
    12301 caacaggggt tgggactaca gtcaattttg ccatatcgta tatttatgag aagcgttttt
    12361 ccaatagctt gatgaaatcg gctacggaag cgtcttctat attccagttc aacaccttgt
    12421 tcagataagt gaccgattcc tcgtacgagc taagatcgtt caggtctgag atcgccttat
    12481 tcattttctc ctcatttcct ccgaataatt cccttctgaa gcggaaacga tcatttaaac
    12541 tgaatgcctt acggaaatca gaaagattct ttttctccaa tatatcattc agtgaaatac
    12601 tggatttatc cgctaatata gttttatgtg gaatctctat ctctttcaag gggattgtct
    12661 cttgtacgat cttttcttct gggatcactt tttcgacaat tggttctact acgataggtt
    12721 cctcaacgac cggttcttgt acctgtacga cctcgatcgt aggggatact tccggagccg
    12781 gttgcacctc cggcatctgt aaaggtttac ttacgggaat agaatcgata agtcgttgat
    12841 gttcctccat ttgtttacgc aaagcctcta actgaaactc ctccagcgta tgaagctcct
    12901 tcaatacctt gtgggtcaac tggaaggtct ggttgaagaa agaggcgaga taaatttccg
    12961 cgtccctcat tccggctacc aacttctcca gctccctgat atcgatcaat agataatcta
    13021 ttttttcctt gtttgccatt tctatatgtt tttcagatgc tataaatcat ccggacatac
    13081 gtatgttttg caacaaaaat aagtatttct tgtcaatgtt gccagtttcg atcttaaaat
    13141 attgtaaatc attcgacgaa ctcgtccggt aaattcacca gatataggtg atgggtcgcc
    13201 cgggtaaaag ccgtgtagag ccacctatag aaatcctcac caagcatttc ctccgtgatg
    13261 taaccgatat cgagaaagac gttcatccat tggccgcctt gggctttatg gcaggttacc
    13321 gcataagcgt attttacttg gacgacgttg taatgaggat ctaccttcat ctttttcatt
    13381 tttcccgcct tggtaggaat gtcctcgtaa tcttccaata tggtgtaaaa gagcttgtcg
    13441 tttagctcct tagggagggc gggggagtcg gtctgtaaag tatccaatag gattttcaaa
    13501 tcgatttcca gatcataatc ttgaaaacga gccgtgatgt cggcaaagcg gaagccatac
    13561 atctccgtga cacggcgtac ccgcatgact tgaatgatct ctccgttcgc tataaagtcc
    13621 atctccttgc aattcgctgt ccaataataa ttgttcttcg ctaccattaa acgatcgccg
    13681 gacgatagct cttcttccct gtataggata cggttacgta tgccgttatt ataaatcgtg
    13741 gctcgtttat tcgagcggga gataatcatt gtctcttcca taccgtcgcg gctataggcg
    13801 gaagatattt cctcaattag ctcatctcca ttgactttcg tgaaatcgga gaagcctttt
    13861 aattgtaatt tcggaaagat ctcgaccgtg tggtttcgta gtgcgtctcg tagccgggta
    13921 gcgttgaaca ggattcccga gtcctcgctt tggcgtacga cttgagttaa cgctatctcc
    13981 caaacctgta ggttgtaacc ccgtaatatc tcgggattca aggcgggact ctccgtttgc
    14041 attaccggag gaagctgtgc gacatctccc attaggataa gacggcagtt tcccccggaa
    14101 tagacatact ggattaaatc gtccaacagg cgtccggaac caaaaacaaa tgaatccaac
    14161 ccctcgttgg cgatcataga agcctcgtcg acgataaaaa gtgtatcttt atgtaaatta
    14221 tctgccggca tgaagcccgt cggctcattg gaaaacgccc gttgacgata tattttttta
    14281 tgaattgtat acgctttttg gccagcgtag cccgagaaaa ctttagctgc tcgtccggtt
    14341 ggagccaaca aaaacgtttt ttgctttagt tcgttaagcg ttttcaccaa agccccgacc
    14401 agagaggttt ttccggttcc tgcgtagcct ttcatcagta gaaggctgtc cggttcctca
    14461 gacaagagaa attcggtaag cgtatgaagc gctaaaaact gatcatccgt cggtttatag
    14521 gggaaatttc gttcgatttg ctggcttatg taactattta tcattttgat cgcaataatt
    14581 ttcgcgataa aggtagtgta ttaaatattc ttttttaaat ttgccgaacg aaataaattc
    14641 aaaaaacaat acaaaccatg aaagttacat taaagatttt attagctgcc gcagttgtac
    14701 tgctagttta catgtgctac aagagcgtca ctggtccgat tgagtatgat gatcagaaga
    14761 ctattcgtga caatgcgatc atcgcccgtt tgattgaaat ccgtaaggct cagatcgaat
    14821 acaagaacat gtataagact catgccggaa gtttcgacga tttggagaaa ttcttgaata
    14881 cggataagtt gccgttcttg atcaaggaag gtgtattgac ggatgagcag ttggagaaag
    14941 gtatgacaga agcagaggct gttaagaaag gtttaattag acgtgatacc atgtgggtat
    15001 tggcgaaaga tactttgcta ggtaagaact atgatgtagc ggctatgcgt tatgttccgg
    15061 ccgttccggg tgaaaagatt actttcaaga tggatacggc tacgttgaaa tctggttctg
    15121 gttatgagat caaagtattc gcttgtgagg ttccttacaa agaatatttg cgtgacatgg
    15181 atgctcagtt gacttataac ttgatcgaca aggcagagaa acaaggtaag ttcccgggat
    15241 tgcgcgtagg ttctttggaa gaaattaata acaacgcagg taactgggaa taatcagcgg
    15301 ctcatatgac tatcagcatt cctgatacgt taactactga taattcggaa aagtatatag
    15361 tgtccatccg gcttcggtcg ggtggacttt ctttttccgg gtatgatccc tcggctggag
    15421 gaagtttctt ttatcgggaa acggaattcg atcgggcggt ctctttcatt tcttccctta
    15481 aggagttttt cttcgctcat gagtttctta cgtggactta taaacggatt aacgtgatct
    15541 gtgtatctcc ggaatatagc ttggtccctg ataattattg gggggacggt aaggaagggc
    15601 gtttattgga tttcagcttt tctacactgg aattgcattg cttaaccgat actttaaagg
    15661 aacaacaggc taaattggtg tttggtgtag acgaggaggt ttacgaattt tgctcccgtt
    15721 ctcttttgca tccttttttc tcccactaca tgacttctcc gctaacgcta tggacaaaag
    15781 aaagtagtgc tagcttaccc cggcaaatgt atgtcgtgat agaacgaaag cggatggatg
    15841 tggcctgcta tgctcaaggg aaactcttat ttgtgaactc ttatccgatc gaccaatcgg
    15901 acgatatagt atactatata ttatatgtat ggaaacaggc gggattggac caagaaaagg
    15961 accagttgct tttagcgggg gaatcttcct cgcgaatgcg ggttctggag cgattgcgag
    16021 cctatttacg ccatgttaag ccggtggaga tcccttcgga agcctatctg ctgggaacgg
    16081 atgtaacgaa agcccctatg gatttaatat ctttattaat atgcgaataa taagcggtat
    16141 atacggtcgt cggcgttttg acgtgccctc ttcgtttagc gcacgtccta cgacggattt
    16201 tgcgaaagag aatattttta acgtagtaaa taatttggtg gatctggaag gtatggatgc
    16261 gttggatctt tttgccggaa ccggaagtat ctcttttgag ttgatctcac gaggatgccg
    16321 gaatgtaacc gccatagaga aaaataacgc tcatgcctct tttatagcca aggtagcgaa
    16381 agagctgaag acggatgcgt tggctctgat tcgtggggat gttttccgtt atttgaattc
    16441 agcccctaag caaagtttcg atttcatctt tgccgatccc ccgtatgcct tgccggagtt
    16501 gccggaaata cccgccttgg ttttcgagcg tgatttacta agggatggag ggatattcat
    16561 catggaacat cctaagacca atgacttctc atctttgcct tatttttatc agcaccgggt
    16621 gtatggctcc gtgaacttta gcatcttcct taaagaaggg gagaaaacag acgcataaat
    16681 gattccgcca tgcgttgctt gagggggcgc tttaaccagc gggaagggat caaacgctca
    16741 cagtgatgca tgtcgtgtgt aaagatgcgt ttcatttgca gggcgaattc cttttgatat
    16801 acgaaagcgt taatctcgaa gttatgctca aagctacgga agtccatatt ggcggacccg
    16861 atgcttgtca atgcgtcgtc ggacacgact agcttggaat gcaagaagcc cggtttgtag
    16921 aggtatactt ttacgccggc ctttaccatc tcgtcgataa aggaatgact ggccatattc
    16981 gctgaacgtg tatcggaacg cttaggcagc atcaaacgaa catccactcc ccctaaggcg
    17041 gcggtttgca acgcttggtt caatccttcg gtaggcagga aataaggggt ttgtataaag
    17101 atatacttct tggcgttggc gatcatgaaa atggtcgctt gcaacaaagt tctccattga
    17161 cctaccggac cgctagtggc gatttgcata atattatcgc tatagatttg ggcggccgga
    17221 tagtaaatcc gatcgttcaa gagtttttta ctaaccacgt accaatcgat gaggaatacg
    17281 gattgaagcc cgtgcactcc tttccctaca aatttgaaat gcgtatccct ccatgtgccc
    17341 caagaggttc ccttatcgta tcggtcggct atattcatgc ctcccataaa cccgacttta
    17401 ccgtctatca cgataatctt gcggtggttc cggtaattca ccttactggt gaaaacgggg
    17461 aacgctaccc tcaagaacgc atatacctcg atacccgctt ccttcatttc cttaaagaag
    17521 ccgtctttta cattccagca acccacatca tcataaagta cacgtacctt cacaccttct
    17581 tttactttct tgataaggag ttgttgcacc tgttttccta tctcgtcatc acagaatata
    17641 taatattgta tatggatatg gtgggtcgct ttctggatct cttccagcaa gtctttgaac
    17701 ttatcggtac cattcgtata aatcgtgatt tgtgttccgt ataggaggga ggattggttg
    17761 gtgttagtca acaaggtcga taaaggttta taggggtccg gaactacgca ggcgtcttga
    17821 ggtaatttac cctcttgcgg ccttttcatg atgcgtttat aggtacgcct cgatatgatc
    17881 cgttgtttcc ggttatcttg tccaaagaag aaatagaaaa gcagtccgat accgggtgct
    17941 aataataaga cgattaccca aggaattgtc tttaacggat tcctattctc tgtaatgata
    18001 actaatacca gtcctaatat agtgacgcta tacaatatga taaatatcgt accaacgatt
    18061 aactgtatat gaatggctgc taacatgaaa ctctctcttt gctataatct gctataattt
    18121 gctaagataa gaatgctttc cgagaatagc aaatttccgt attctttttg gactgtatag
    18181 aagggccaaa aagtaagtta acttaaatgg caaagtaagc taacttaaat gcccgagtaa
    18241 gttaacttac tttgccaacg aagctagctg actttggatg cggggttatg tacatcttaa
    18301 aataatgagg tcgttctcta aatataaagt gtcatttgtt gattttggcg aaggctatta
    18361 tgagaagtat ctatgataac aataaaaata tttagattga aaacgactgt aaaaaacgat
    18421 cgtttcaatt agtcgtttgc aaaggtaggc atttctccga gaccggcaac cttttccgat
    18481 taaattttgt cctgctatat atcttcttct caacaggata gattaatcaa agtatcacga
    18541 atatgacaaa agagcatcat ctttttactt tctaaaaaaa tgcaagatct aaacgatcgt
    18601 tttcactagt cgttttttat gtggaagggt aagaataaga aaaacagtaa accaatgata
    18661 acttggaatc aaactctaga gatatgaata gaaagtcttc tatacgagcc attttactcc
    18721 gtaaggaatg ccttttattc tttttgctac tattgcctat gtttacaaag gcccaatata
    18781 ataaggtata tgcggatatc accgcaaata tgctggtcga tatgggtttt gagaatgttg
    18841 tctggtcgga agacgagaag gagagagtgt atgtcttgga gaatacccct tggcgtttgc
    18901 agggtgtggg actggcccat gccatagacc gcatccagaa aacaggcttg ccggagaagg
    18961 gcaaatcctg ccgtatcgtc gtattggata ataatatacc gcagatctca ttgatctata
    19021 cggcaaatcc ggacagcttg aaggcggctc ccggctccta tgcggcccgt tccgcctggg
    19081 atgctactta cgatctgggc gatagctggg ataaggtgaa gaaagagtac cgtatgaata
    19141 gctccttatt taaagtagac gtggtggttt atccggagtt gtatctgaag aacctcatta
    19201 tcacgcaaat ctaccaagta ttattcaacc tctcgcctgc gatcgaggtc tctttctgga
    19261 atgggatgaa gctgacggcg cagatggtgt ttcctatata taatgatgga tatggaaagc
    19321 ggatggataa gattcacccg ggaacaatcg ctctttctca atcattccgc ttaccgatgc
    19381 gtacgtttgc gagagtaagc gtagggttgt ttgattcgga tcgctatggt atagatttga
    19441 aggcggtaca ttatttcaag gatgaacgtt tttctgtgga agggcggatt ggttgtaccg
    19501 ggacggggta ttggaatggg ttcgaatttc attatggtaa gcatcaacga atcacttggt
    19561 cgttgggggg gagtttctac tggccaaaat acaatacgca gatatcgttg aaggcggaac
    19621 aatatttatt gcatgaggtt ggaggacgaa tcgacttgat tcgtcatttc cgatattgct
    19681 cgattggttt ctatgcgatg aaggcgcaag gtgctttgaa gaatggaggt tttcgcttcc
    19741 aagtggctct tcctccctat aaatacaaac gtaaatatgc aagggtgaca acttccgaca
    19801 attggggtat gtcttataat gccggaaacg aacggtatta ttataagaac tattatgcgt
    19861 tgccggaaga taacatgatg aagcaaaatc aattcaaccc gtactttata aagtcggaat
    19921 tactcaattt ttaaatagtt ttattatgag aacaattaca aagttacaga ccttattggt
    19981 cttgtttttg acaacagcca tgatcggttt cgctggctgt aaggatgacg atggggatgt
    20041 gcctgggcct actccgggca atgaagccac ttatgcgatc agtggtaaag tgacagacgt
    20101 ggacggtgct gctatggcgg atgtgaatgt cgcgttatct ggagctaaat caatgtccgc
    20161 taagactgct gctgacggac agtatacttt cgacttggga aagaatgctg ccggagccta
    20221 taaggtgact ttctctaaag aaggttatat cgagagaagc tatgatataa ccgttaagaa
    20281 ggtagaatcc ggcttgggtg agaatatcca gaatgccgtg atggaaaagg gaacaactcc
    20341 cgagcctacg ccggaataca agaaggcgaa gtatttcttg accgttagcg tgaaagacga
    20401 ggctggaaaa gatattaccg cttccgatct ttcagtgctc gttaaattag gtgacaagga
    20461 aatcgctaag gagaacaagg ctagctttga gttgtctgac gtggcaacgg gtacgtatga
    20521 tattaccgct acggcttccg gttatgagaa gacagtcgct aaagttgttg tttctccggt
    20581 tgaggaccaa gagaaggctg agggtgacgg tgatacattt gacgtgaagt atccggctaa
    20641 tttggtattg aaggcttcta cgcctactcc gacaggtcct tcttatattg tggaaggtga
    20701 tgttaaggat gtgaatggta aagctgttaa tgcgacaatt actttgtcgg gcgctttaac
    20761 aaagatgatt taccgttctg ggtttgagac tcagactgtg acaggctctc attatcgttt
    20821 tgtaattcct caagatgctg ttacggctca aatgagattt acaattcgtg ttgtcgcaga
    20881 gggatatgcc gcatattctt acaactttac tttggatgag ctgaaaccgg gtgagactgc
    20941 gaatgtgatc gctgatttcc atttgacacc tgctacaccg actccagatc cgactccaac
    21001 cccagaccca accccagatc ccgatcctgt aactaagggc ggagaggttt ctaaaccgat
    21061 tacagaggtg aatccggaaa tcggcgttga gcaagtaggt aaggtcgagg aaaagattga
    21121 agctaatcaa gagaaaaagg tcgaggtaaa agatgagaca ggaaagacag tagaggttgc
    21181 tgtaaagata ccggaggctg ttgcggataa atatgaatct ggcgcaaatg tggctgttgc
    21241 caatcctgag acattcgctg caagtttggg caagattgaa tctgtagtag aggacaaatc
    21301 tgaggttgat gaaatttcat tctctaccga aggttctaat acaggtgttg ttatcgtgac
    21361 tcctaataac actacggagg atttctctat taaacgtgat gctacggtgg aattaacggt
    21421 taatagtgag aaagcagcgg agattgagac tggaacggat gctagcacag tagcagaaag
    21481 cggttctcca gccgcagctg ttacccgtat ttatacagga aagcctgacg gtacggttat
    21541 tattccggct atggtgatta aagcttccgc tcctgcggac ttcaagaacg tatccgatat
    21601 gcctctaaac cttctgtata agaatggaga taattgggta gttgataaag atgctaaagt
    21661 agagcttaag aatggccaat tgaatatccc tgtagctcac tattctcaat tcagcgcagg
    21721 tttattgatg gcggttaaga ctacaaccgc tccttctgat agtacgttct ttatcgagaa
    21781 atcggagttt ggagaataca acaagatggt ttcggtagag tttacttata atgcgacttt
    21841 cttaaataat aaagatttgg ataaagctgt cctttcagtt ccgtatggaa atgcggctaa
    21901 ggattatttg aagaactgct taggcaagaa aatcaacgct gatggtggtc tgatctcttt
    21961 caaaaaatca tatgacgtga aggtcgacga aggcatgact cttaagggtg taaacattac
    22021 tgttaagtat gcggctaaag aatatgttgt ctactatctg aataaaggtg gttctttgga
    22081 atcggtatct gttacggtgt tgagcgtgaa agaggctaat cctgctcctc tttatgagca
    22141 aagccacgga catggccatg gcaatggaaa caatgccgga ggcggtattt ttggtaaata
    22201 atcaacaaga agactgacct ccctataaat aatgttgagc cggaagttta taagtaaaca
    22261 aagaaaaatg aagaaattac tcttattgat catattctta agttgctgga ccttacttcc
    22321 ggctcaatta tcttatggca cgacagggct attgcatgct ccgtccgccg atatgcaaaa
    22381 ggacaagacc gtgatgcttg gcggaaactt cttgcattaa gagcttacgc ctcccaagtt
    22441 taattttaat acgtggaatt attatttgaa cgtgacgatc ttcccgtttc tggaagtagc
    22501 gtatacttgt acgctgttta cggccgagag ccttggattg gataagcatg gctattccgg
    22561 attcacgaac caagatcgtt atttctccgc ccgcttacgt gtgttgaaag aaagcaaata
    22621 catccccgct gtcgtgctgg ggacttcgga cccttttacg tcatccgggc ataaattcgc
    22681 ttcagccata gggaacggct atttctgccg ttattatctg gccgctacca aacattttca
    22741 gctgggaagg ggaaccttag gcgttcattt atcctatctg tataatcgcc gtgaggatta
    22801 tcccttgaac ggtgtggcgg gaggtatcac ctacaatcct tcattcgccc cgcatttgaa
    22861 cgtcatagcc gaatacgatt cgaaagactt cgctatggga gccacttacc tgctattcaa
    22921 tcatatacat tttcaattcg aattgcagcg aatgaagtat ttctccggtg gactatgcta
    22981 taagatttat ttgagataaa aagaggttca gcctttgtcc gtttttaatc cgcttggagg
    23041 cgaacggtta ggctgaacct ttttatatct tgttacgctg tcgcgctagc catatctacg
    23101 gctttattcc ccgatgaaat tcttgcgtat aagctcggca gatttgtatt cctcttccag
    23161 atacgtctca atatgccgtt tcttcttatc ctctaatatc tcgttaatag cgattaagat
    23221 acccgtttct tccacctctc caaactcatg gttgatcgct gtgccgaata cacgcatctt
    23281 aggcgacaag ctcatgtaag catttaccaa aggaggcacg ttgatgccaa atttacgaac
    23341 ctcttggttc aataccttgt agttatcctt gaaattatcg tgagggaaaa gagatctcat
    23401 cttctctaca tccatattag tctccaaagg atataccgga gtgatcagtt ggtctgcgtc
    23461 cgggaaatgc aatccgagga agtataagat catattacgg gcctcttggt tgtacgtatt
    23521 gtacatagtc accttcccga aataatacct caagctcgga tcaaccacgg ataaagcccc
    23581 caatccatcc cacaggttat ccaacacgaa taagcctttc gccccggaac gggtggattg
    23641 atactccaga gccacgaacg agcgtcccaa ctctaccgta taaggaagga tctccttgat
    23701 aaatttctct gagaaattaa acaagtgcga ggtcgccaag atcggtttac cattctcgtc
    23761 gaacttaacg tccgaaccgc aaaggaaacg gtatcccccc aagatctgct catcttccgg
    23821 gctccagaca atcaactggc ggtaagcgtc ttccatcgtg tcatactcat cgatatccac
    23881 agggaatccc gtgccacccc cgtaataacg gaaagcgacc tcccgcagac gccctatctc
    23941 ttgcatgaca ttgggtgagt cgtgcgccgt gacgatataa atctcattct tcgatttatt
    24001 ggtacttctc aacctcttct ctttggtcaa ttcagccttc agtagtgccc tgtctatggg
    24061 attgataatg tcttgcatat gtttcgtctg ttaatccttg agtttgtaaa ccttgttttt
    24121 tatccactca gcccattcgg cgggtttctt gctattgtcg aatgtctgcc aagggatagg
    24181 cttcccgaaa taaatccgga aggtcttatg tttgctccgg aacatctcgt ccggtaaata
    24241 aatcatctca taattcatct ttatacccag cgccttgcgt atccgggcga ggttgtagaa
    24301 gaaattggaa ttcttcccgt cgaaatagac cggtacgata tcccgcttgt attgcaccgc
    24361 cttctggatg aacgatttct tccactccaa gtcttgtatc ttgccaccaa tcttgcgaga
    24421 gcataatcca gcggggaaag tgatgatctg gtcgtccgag gcaaaagcct cctccagcat
    24481 ccgtgcgttg tcctttcctt gggtgccgtg tttgttgatc ggtacaaaga tggattttag
    24541 attggagaga taaagtaata aatcattgac cggatacttg atgcggcctt cgaaccggga
    24601 accgataacg gcggagagac agataccgtc caatcctccg agcggatggt tggaggcgaa
    24661 gatatagcgc ccttcggtcg ggatgttctc cgcatgtacc agatcgaggg taaggtcaaa
    24721 atagccgata agctcacgca tgaaatctac cccttcctta tcgtggtaac gggttaatat
    24781 atcattcagt tcctcttgat gaaccgtgcg aatcaagtag tccacgataa atcccggaat
    24841 cttgcgtgac gccttgggcg ccttttgtgc caatacttgc ttaatatcta tctttgtcac
    24901 accttgtttt gccatctata taagcttgtc aaggggcaaa gataaagtta ataattaaaa
    24961 cgagagaggt ttgagtgaag tttttgcttt ttcgccagct atcttggcct tttccccttg
    25021 atcttttagc cgctaccatt agggaggtta gtccccggga gcttgactat cggttatcta
    25081 acggctgttg gacgatcatg caccaactgt tagaagatca tctaccaact gttgcatgat
    25141 catccaacgg ccgttagaag atgaaggtga aaggaagaat tggttaacgg ataccggtga
    25201 aaagcgtaag agataaggac gaaaagacga agggttaacg acctgttgat aactttttcc
    25261 tacttttctt atataaatgt tggcgggtaa ttttggaaat gtgtactttt acccaccgat
    25321 aaggcatgtg cgtgcgtatc aaaggagtac ggcgcttgat tttaagagga agtttaacgt
    25381 aagaacgacg aatggaagaa aaagatagtt gctatcatgt accggtaatg ctgcgggaaa
    25441 gtctggaggg attggatatc cgtcccgacg ggatttacgt ggatgttacg tttggcggtg
    25501 gaggacattc ctgcgagata ttgaaacggt tgggtagcga gggcgaactt tacggctttg
    25561 accaagacgc ggacgcggag cataatatcc cggcagatcc acgattcact ttcgtgcgca
    25621 gtaatttccg ttatttgtat aattttatgc gttactatgg agaaagcggg gaggtagacg
    25681 gtctgttggc ggatttaggt gtctcttccc atcatttcga cgataaggat cgcggtttct
    25741 ctttccgttt cgacggggcg ttggatatgc ggatgaatac gcgtgcgggg cagaccgccg
    25801 ctgatatcgt gaataattat acggcggagg cgttggccga tgtgttttat ctatatggcg
    25861 agctgaaggt gtcacggaaa ttggcctctg tgctggtgaa agcccgtgag acaaagaaga
    25921 tagagacgat cggggacttc ttggaggtga tcaagccgtt tacgggaaag gacaaggaga
    25981 agaaattctt ggcgcaagtc tttcaagcgc ttcgtatcga ggtgaacgat gagatgaggg
    26041 cgctaaaaga gatgctgcgg agtaccttgc gggtgttgag gccgggagga cgcttggtgg
    26101 ttatcacgta tcactccttg gaagatcgtc tggtaaagaa ctttttgaag accggaaact
    26161 tcgaggggaa gtgcgagcag gatttcttcg ggaacgtacg atcgcctttc cgcttggtca
    26221 ataataaggt gatcgtcccg accgacgagg aggtggagcg gaatccccgt tcccggagcg
    26281 ccaagttgag aatcgctgag aaggtataag gagaaataga tatggaagaa aacggacaac
    26341 ataagaaaac gaggaagaag gagaagcgtc tttcgttctg gtatatactc ggtggcggcg
    26401 tgctgaaaga ggattttatc ttgaggcata cgcgcatgat cgtgttactt gtcgtgttgg
    26461 cgtttttctt tatcggtaac cggtatactt gtatgcaaaa gttgcgtgag atcgaccggt
    26521 tgcaacagca attgagggat gtgcgtttcg aggcgttgtc gatctcatcc gagttgaccg
    26581 gcaatagccg ccaatcgcaa atcgagttgc tgatcgagga gcaaggcatt gatctggagg
    26641 gtgcgaaaac ccctccttat gagttatata agtgagataa ggtgtaaatg ggtatgtctg
    26701 aagaaaacga accgaaagaa atagagccta aaagtagccg gattttattc tgttacttcg
    26761 tggtcgtgct gttgctgggg cttgtggccg taggaatcct gttccgtgcc tttgatacgg
    26821 ccttcgtgga gagggataaa tggatgaagg tggccgagag ccagaaacga ccgaaccgtt
    26881 tggtgttgcc cggacgtggc aatatctatt cgtcggacgg taagttgatg gctaccagcg
    26941 tgcctcgtta ttatatgtat atcgacttta aggcggatgc gtatactccg gctaaggatg
    27001 ccaagtataa ttggctggat acgttcaaga cgtccaagaa ggacggggtg gactcgttgg
    27061 cgttttatct ttcccgtaaa ttgaaggatc gtacgccggc gggctataag gcttatctgt
    27121 tgaaagggct gagcggtaag agtcgccagt tcccgattta tgcggggaag gtctcgtatt
    27181 cggacttgaa ggagatccgt aagttcccgt tccttcgtct gggacgttat aagagcggtt
    27241 tttatacgaa ggagatggtg cagcgccaga aacctttcgg gaccttggcg tctcgtacga
    27301 tcggtgatat ctacggagag atcgaggagg gtggaactac gaaggggaag aatggattgg
    27361 agttgcaata cgattcgctc ctgcgggggc aggccgggtt gagctccgtt cgccgtgtcg
    27421 gtggaggctg gacgaacgtg atcgaggtgg acccggtgga tggcatggat attcgcacca
    27481 cgatcgatat caatatacag gatataaccg agaaatcgct ggtcgataaa ttgaaggcga
    27541 tcgatgccga gtctggtacg gctgtcgtga tggaggtcga gaccggagag atcaaggcga
    27601 tcacgaatat ggggcgtatc cgtgagggcg tatatggcga gacgaagaat catgccgtgg
    27661 cggacgagat cgagccgggc tctactttca aggtggcctc tatcatggtg gccttggagg
    27721 atggtttatg caatccggga gatacggtcg atgtaggcaa tggtatatat atgtataagg
    27781 gtgcccgcat gacggaccat aatatgaata aaggcggata cggccggatc tcggtggagc
    27841 aggcgatttg gtattcctct aatatcggtg tagccaagac gatcctgaaa ggttattcgg
    27901 ataacccgac aaagttcgtg gagggactgt accgtatcgg tatgaacgcg gatcttcgtt
    27961 tggagatacc gggggcggga cgtgccaaga tacgtcgccc ggatgatacg acccgttatt
    28021 ggtccaagac caccttgcct tggatgtcgt tcggttacga gacgcaggta ccgccgatca
    28081 atacgctggc gttctttaac gcgatcgcga acgacgggaa gatggttcgc ccgatgttta
    28141 cgaaagagat cttacataac ggcaagaccg tgcagagttt ttccacggag gtgatcaact
    28201 cttcgatttg ctcggatcat acgctggcgt tgataaaaga tatgttgctg ggagtcgtgg
    28261 agaaagggac cggtaaggcg gttcattcgg atattgtccg gatcgccgga aagaccggta
    28321 cggcgcagat cgctacgggc ggtgtctacc gtacgagcgg gcaccaagtc tctttctgtg
    28381 gctatttccc ggccgatcat ccgaagtatt cttgtatcgt ggtgatccgc cgtccccgta
    28441 ttggttatcc ttcgggcggt acgatgtcgg gaggcgtggt gcgtgcgatc gccgagaaga
    28501 tatacgccag ccatatgtcg ttcgatgtcc gggatatgga acgggattcg atggccgtga
    28561 tggtacctcg tgtgaaaggc ggcgatctga gggcggtaga ggacgtatta gatgaattgg
    28621 atattaaggc ggatacggac agtttggaga caaagtgggt cgtagcctcc gccgagcaag
    28681 aagagaataa ggtgaaatta agcgatctga cgattcgtga gggcctggta ccccgggtag
    28741 tcggcatggg tgctaaagat gcggttttct tgttggagca agccggtctg cgtgtctctt
    28801 tgtcgggtgt cggacgggtc gtttcgcaga gtattcaacc cggacagcga gtgtctaagg
    28861 ggcagaccgt attattaaca ttgaaatagg tatggaacta agggatttaa tcggtgcgtt
    28921 ggaagctcct atgttgatgg gggcggataa tgtggatatc acgaatattc aatcagactc
    28981 tcgtcgggtg acgaaagggt ctttgtttgt cgctgtgaga ggtacggccg tggatggcca
    29041 tgcctatatg gacagcgcca tagagaaggg ggctgtcgct atcgtatgcg aggaggctcc
    29101 gtcctatttg gaggggagat gctcgtttat cgtggtgaag gattcggcgg aggcgctggg
    29161 tcttttggtt tcccgctggt atggtgatcc ttccgggaaa ttggtgttgg taggcgtgac
    29221 gggtacgaac gggaagacta cgatcgctac cttattatat gagatgttcc ggaagatggg
    29281 gcataaggtg ggattgcttt ccacggtatg taattatata gatggcgagg cggtaccgac
    29341 ggatcatacg acaccggacc cgcttacgct tcattccttg atggcccgga tggtagaggc
    29401 cggatgcgag tatgctttta tggaggttag ctctcattcg atcgatcagc ggcgcatcag
    29461 cggcttgtct ttcgacgggg ggattttcac gaacctgacc cgcgatcatt tggattacca
    29521 taagaccgtg gagaattact tgaaagcgaa gaagaaattc ttcgatgacc tgcctgccgg
    29581 gactttcgcc ttgacgaatg ccgatgataa atccggcttg gtgatgttgc agaatacgaa
    29641 ggcgaaaaag ctgacctatt ccttgcgtac cttggccgat ttcaagggaa agatattgga
    29701 atctcatttc gagggtacag acttgatcat taacggtcgg gaggttatgg tgcatttcgt
    29761 gggacgtttc aacgcttata acttgctggc cgtgtacgga gccgcggttt ctttggggaa
    29821 agatcccgag gaggtgttga tcgtgctgag cacgcttcgc tccgtatccg gtcgcttcga
    29881 gacgatccag tctccgctcg gttatacggc gatcgtggat tacgctcaca cgccggatgc
    29941 cttgacgaat gtactgaatg gcattcatga ggtattggat gggaaaggac gtatcattac
    30001 cgtggtaggt gccgggggaa accgggacaa ggggaaacgc ccgctgatgg cgaaagaggc
    30061 tgtcaagctg agcgatcagg taattctgac ttccgataac ccgcgctttg aggaaccgga
    30121 tgatattatt aacgatatgg tagccggatt gacgaaaatg gatatggaac gtgccttatg
    30181 tatcacggac cgtacgcaag cgatcaagac cgctacgatg ttggcgaaga aaggggatgt
    30241 gatccttgtt gccggaaaag gccacgaaga ctatcaggag atcaaggggg tgaaacatca
    30301 ctttgacgac cgtgagaagt tacgcgagat tttttcgaca caacaatcat aatatttaag
    30361 acgacatgct ttattatctt tttaattatt tggatcagtt ggatttcccg ggagcgggta
    30421 tgtttaagta cgtatctttc cgctcgggat tggccttgat cttgtccttg tttatctcta
    30481 cggcgatcgg ccggcgtatc atcgataagt tgcaaatgtt gcagatcggc gagacggtga
    30541 gaaatcttgg gctggagggc cagatgagca agaagggaac gccgacgatg ggaggtatta
    30601 tcattattat cgctatattg atcccgactt tactgtgtgc caagctgaat aatatctatg
    30661 tgatattgat gttggtgact acggtttggc tgggagcctt gggattcgcg gatgattata
    30721 tcaaggtgtt caagaagaat aaggagggca tgcacggacg tttcaagatc gtcgggcagg
    30781 taggactggg cctgatcgtt ggcttggtat tgttcatgag cccggacgtg gtgatcaagg
    30841 agaatatgga ggtgcgccat gataacgtga tcgaggaggt gcgttatcat acggtggaga
    30901 ccaagtcgac aaagacgacc atcccgttct tgaaaaacaa taatttcgat tacgccaact
    30961 tggtgaactg ggcgggcgat tataaggagg aggccgcgtg gctagtgttc gtgctgatgg
    31021 tgatctttgt ggtgaccgcc gtgtcgaacg gagccaatat gacggatgga ttggacggct
    31081 tggctgccgg gacatcggct atcatcgggg tggcgctcgg tattttggcc tatatgtcat
    31141 cccactttga gttcgcctcg ttcttgaata tcatgtttat acccggcgcg gaggagttgg
    31201 tggtttatgc cgctgccttt atcggtgcca cggtcggttt cctatggtac aactcgtatc
    31261 cggcccaagt atttatggga gatacgggta gcttgacctt gggaggtatt atcgccgttt
    31321 tcgcgatcat catccgtaag gagttgttga ttccgatcct ttgcggtatt ttcttggtgg
    31381 agaatatatc ggtcatgttg caagtggcct actttaaata tacgaagaag aagtatgggg
    31441 aaggtcgccg tatcttcaag atggctcctt tacaccatca tttccagaag ccgggaaacg
    31501 cgggtataca ggcgttgatc caaaaaccgt tcaatgtcgt gcctgaatcg aagatcgtgg
    31561 tccgtttctg gttgatcggt attattttgg ctgttatgac gatagttacg ttaaagatga
    31621 gataaaagat gagtaagaga atggttatat taggggccgg ggagagtggc gcgggagccg
    31681 ctgtcttggc gaaggcgaaa ggattcgacg tgttcgtgtc cgataaatcg tctatcaaac
    31741 ctaagtataa ggagatgctg gacaaccacg ggattcgttg ggaagaggga cagcataccg
    31801 aagccgacat cttgaatgcc gacgaaattg tcaagagccc gggtattccc gacaaggctc
    31861 ctatcataca gttattgaag aagcaaggta cgccgatcat ttccgagatc gagtttgccg
    31921 gaaggtatac ggactcgaag atgatttgca tcacgggtag caacggcaag acgacaacga
    31981 cgatgcttac gtatcatata ctgaaagaag cgggcgtgga cgtgggcttg gccggaaatg
    32041 tcggaaacag cttggcgctt caggttgcgg aagatccaca tgcggtctac gtgatcgagt
    32101 tgagcagttt ccaactggat aatatgtacg actttagagc ggatatcgct attatattga
    32161 atataacacc ggatcatctg gaccgttata actatgagat gcagaattat gtagacgcta
    32221 agttccgcat cttgcaaaat cagacgaagg acgacgcctt cattttctgg aacgatgacc
    32281 cgatcatagc ccgtgagatc gccaaacggc atcctgaggc tactctttac ccattcgccg
    32341 agacatatga gaacggcgtg aagggatata cggaaaataa tcaagtagtt attgaaacgg
    32401 taaacggaac atttacgatg gaacaagacc tattggcatt gactggtacg cataacctgt
    32461 ataactcttt ggcttcgggg atagcgtcca agatcgtgga cattcatgat gagaaaatac
    32521 gtgcctcact cagtgatttc acgggtgttg agcaccgttt ggaaaaggtg cttcgcgtgc
    32581 gtggtgttga ttatatcaat gactcgaaag ctacgaacgt aaactcttgt tggtatgcct
    32641 tgcagagcat gacgaccccg gtcgttttga tcttaggggg cacggataaa gggaatgatt
    32701 actcggagat cgaggaatta gtgaataaga aggtacattc attgattttc atgggtgtgg
    32761 ataatacgaa actgcatgcg ttcttcgacg ggaaagtggc gaatattgaa gacgcccgct
    32821 cgatggagga ggctgtggcg aaagcttata agatggctca taagggagat acggtattgc
    32881 tctctccttg ttgcgccagc ttcgacctgt tcaagagcta tgaggatcgg ggcgatcagt
    32941 tcaaggcttg cgtacgtaat ttgtaataaa ggataaaatg gatctggcga gtaaactgtt
    33001 taagggcgac cgggtgatat ggatcatctt catgttcctg tgtcttatat cggtggtgga
    33061 ggtgttcagc gcgaccagta cgatcgctta taagaacgcg aatcactggg cgcctatcgt
    33121 acggcacgcc acctttttat tggggggttt cgtcatggta ttgctgttac ataatatacc
    33181 gtgtcgtttc ttctctgcgt ttattatatt attgccggtc tcgatgttga tgttgatcgt
    33241 gacgcccttt atcggcgtgg acgctaatga tgcgcatcga tggctggaaa tcatgggaat
    33301 acagttccag ccttcggagt tcgggaagct ggcttgtgtc gtgtttgtcg ctttcttgct
    33361 cagcaagcgg gggaaattaa cggagaacca gatctttaag tatatactga ttggagtagg
    33421 actcacctgt gtcttgattc tgccagagaa cttctctacg gcgtttatgc tattcggggt
    33481 ttgtttcctg atgatgttta tcggtcagtt gccatttggt aagttggcga agctggcggg
    33541 catcttgatg ttggcgttgg tgttgttctt ggtgttgctt aagtttacgc cagccgctat
    33601 tactcagtat ttgccggatc gattcgttac ttggcagggg cgtttggagc gtttcttcga
    33661 cgggcataag gataatttgg atgagagtgg tacgtataag ataaccgatg ataattatca
    33721 ggtaacccat gcgaagatag ctattgccag gggaggcgta ttaggacaga tgcccggaca
    33781 tggccaacag cgtgacttcc tgccacaggc gtattcagat tttatctatg cgattatcat
    33841 agaggaactg ggtatcgttg gggggatctt tgtactgttg ctttatataa tgctgctagt
    33901 gcgggtcggg atgatcgccc ggaaatgtga taaatcattc ccgaaattcc tagtgttggg
    33961 atgtgggttg ctggtggtag tccaagcctt ggcgaatatg gcggtagccg tgaatttagt
    34021 gcccgttacc gggcaaccga tgccgttggt gagccggggt ggtacgtcta cgcttatatc
    34081 ttgtatctat ttcgggatca tattgagcgt aagtcgtttt ggagccaata tcggaaatga
    34141 ggatgaggaa gaggaggata cggagaatcc agagaatcct tccgacgagc catccggaga
    34201 gacaataaat caggcggtcg agggagagaa agaagataat ccgctgtcgg ctgtcgaaac
    34261 gataactgta gagtcaaaag tatgagaaag taccggatca taataagtgg tggtggtacg
    34321 ggaggccata tcttcccggc catatctatc gctaatactt tcaagaaacg ttttccggat
    34381 gcggaaatct tatttgtggg ggcggaagac cgcatggaaa tggataaggt tccggcagct
    34441 ggttataaaa ttgtaggttt accagtgagt gggtttgatc gtgcccactt gatgaacaac
    34501 gtgaaggtca tggctcgttt agcgaaaagc ttgcgcttgg cgaggaagac gattcgtgag
    34561 ttcaagccag atatagcggt cggcgtgggc ggttatgcca gtggaccgac tttatggatg
    34621 gcggcttcgc aaggtgttcc tgcgttgata caggagcaaa actcatatgc cggtgtgacc
    34681 aataagttgt tggcgaagaa agcgagcaag atttgtgtcg cttacgaggg catggagaag
    34741 ttctttccgg cggataagat cgtgattacg ggaaatccgg tgcgacagga tttggaagag
    34801 gcgctgagta agaaagagga ggcgttggcg ttcttcgggc tttctccgga gaaaaaaacg
    34861 atccttgtgg taggtggtag ccttggcgca cggacgatta accggagtat tcaaggggat
    34921 ctggataagt tcttcgcctc ggatgtacag gttatttggc aaaccggtag gtattattac
    34981 agcgacgctt ccaagcattt gaaggcgtac cggggaatgc cggtttggtg ctcagacttt
    35041 attacccgta tggattatgc ttattcagcg gccgatttgg tgatatcccg tgcgggggct
    35101 agttctatct cggagctttg cttattagga aaaccggtgg tcttggtgcc ttcgccgaat
    35161 gtggcggaag atcatcagac caagaatgcc ttggccttgg tccataagga tgccgccgtt
    35221 atgatcgccg ataaagacgc ggaaaaggat ttggtgccta ctgccttgaa gatagttcat
    35281 gacgatgaac gtttgcatac gttgagccgt aatatcgaga ccttggcgca acgccatagt
    35341 gcggaccgta tcgtggatga gattgttaag attatagata agaaataagg aatatggata
    35401 taaataaagt gacagcggtg tatttcgtag gtgccggggg cattggaatg agtgccttga
    35461 tccgttattt cctcgctaag ggaaaacgag tgggcggata cgataagacc ccttccgatt
    35521 taaccgagga gttgaaaaag gagggagccg atattcacta tgaggataat gtagctttga
    35581 tcggggaggc gttcaagtcg cccgatgata cgctggtggt ttatacgccg gcggtcccgg
    35641 agtcgcatac ggaattgacc tatttccggg cgcacggttt tgaggtgatg aagcgggcac
    35701 gtgtcttggg agagattacg aaaagcagcc ggggtttatg cgtggcggga acgcacggca
    35761 agacaacgac ctcttctatg ctggctcatt tgctgaaaca atcgccagtg gattgcaatg
    35821 ctttcctcgg aggaatccta aagaactacg agagtaattt gatgttgtct gatacgagcg
    35881 actttaccgt gatcgaggcg gatgagttcg atcgttcttt tcattggctt actccttata
    35941 tggcagtgat tacttccgca gatccagatc atctggatat ttacggtacg gcggaggctt
    36001 accgggagag tttcgagaaa tttacctcct taattcgtcc cgatggttgt ctactgatca
    36061 agaaaggaat caacgtaacg ccccgtttac aggagggtgt caagaaatat acctattccg
    36121 ttacggaaat agcggacttt tacgctgaaa atattcgtat ttgcgacgga aatattacct
    36181 ttgacttcgt tggtccggaa atccgtattc ctgatgtgga attaggtgtt cccgtaaagg
    36241 ttaatataga gaacggggta gcggctatgg cgatcgcttg gttgaacgga gtgaaaccgg
    36301 aggatttgaa aaagggtatg gctacatttg ccggacctcg ccgccgtttc gatttccatt
    36361 tgaagactga tcaagtggta ttgatcgatg attatgccca tcatccggcc gaattgcgac
    36421 agagtatctt gtcggtgaag gaattatatg cgggtcgtaa ggtgacaggt attttccagc
    36481 cgcatctata tacccgtacc cgggatttcg ctggtgattt cgccgcgagt ctctctttat
    36541 tggatgagtt gatcttgctg gatatctatc cggctcgtga ggaaccgatt ccgggggtga
    36601 gctctcggat catttttgat aaggtgacga tcccttccaa gacgctgtgt aagaaggaag
    36661 agcttttgga cgtggttgcc gccgggaaat atgaggtagt attaatggta ggcgccggta
    36721 atatcgaccg tttggtggag cctgtaaaag agattttatg taaacaaata aggaaaccgt
    36781 gatccgaata atttccatag tagtagccac gttgttgttc tgttacatcg tgtttgtgtc
    36841 gtttttcttt cgggaaatac gtcaggactc tatttgccaa gatctgcaag tcgtggtgaa
    36901 agacagtctg gataaacact tcgtgagcga gagtgacctt gtgtctatac tgaagaaagc
    36961 tgggctagat ccgatcaagc ggtcaatggc cgacgtgaat acggatcgga tagagacgga
    37021 attgcttaag aatgagatga tcgctcaagt ggaggcgtat aagactcctt cgggtattat
    37081 caagctagag gtcatgcaaa agatgcctat cctccggatt atgggcgtaa gaggtagtta
    37141 ttacgtggat aatctgggaa ccaccatgcc gatcagtcgt cggtatgccg cgcatgtgcc
    37201 aattgtgagt ggatatgtgg aaaaagagct tgcggtgacc gacttataca aatttgcatt
    37261 atttttgcaa gagaatgagt tctggaatga ccagattgaa caaatctatg tctatccgga
    37321 taatgatata gaacttattc caagagtggg taaccaccgg atcatgttgg gtactttgga
    37381 tgaattcgaa gaaaagcttg cgaatttaaa gcttttctat gaacaagcga tccctaaagt
    37441 gggttgggaa aagtacagta tgattaattt aaaatataag aatcagattg tttgtactaa
    37501 aaaatagatg atatggcata cacagacttt atagcagcta ttgacctagg tacctcccat
    37561 atggtaggaa tggtggggac taagaatgcg acgggcgctc tttcaatcat cgcctacgaa
    37621 gttgagaact ctggcacctg catacgaaga ggatgtgtat ataacgtgaa ggagacggcg
    37681 agtaagataa aacgcttgat cctcaagttg gagaataaac tgggggggac caagatcggg
    37741 caggtatatg tgggactggg tggccagtca ctccgttcta tcgagcatac ggtttgcaag
    37801 gtattgggaa cggaaggagt ggtcacggag gagatcatag actctcttta tcaagagtgt
    37861 aaggattatc gtccggatat gttgaccgtt cttgacgtgg tttctccttc ctatttttta
    37921 gatgataaac cagagtccaa cccggtgggt gtgccttgta gccgtatcga ggctcgttac
    37981 aagttgattg ttggacgtcc ttcgttgaaa ttaaatattg tcaatagcat ctcggaacaa
    38041 gcgaaaatcg agatcgccgg tattctggtg tcacccctcg cgttgggaga tgttgtcttg
    38101 agcgacaatg agaaggactt gggttgcgcc ttgatcggtt tcggtgccgg cgtgacgacg
    38161 atatctgtct ataagggtgg taagttggcc agcctttccg ttgttccctt tggaggtaat
    38221 ttgataacaa aagatataac caatctcagg gtcgtagagt ctgaggcgga acgcttgaag
    38281 atcacttatg gtagcgcgaa agcggaccgg gataatgata tgaccatcca agtgagttta
    38341 gcggatggaa tgggcttgcg tgagattaag ctggccgagt tgaacggtgt gatcgaggcc
    38401 cgtatggatg agatcttaga gaatgtatat gctcgtctgg aggctacagg cttgatgagc
    38461 gttctcggtg ccggcatcgt gattacgggt ggaggcgccg ctttgaagaa tttaccggct
    38521 gttatgagcg aacgcttgaa gatggaggtt cgctattcag cggttcgcaa gggggttgtc
    38581 gctagtggtg atttagtggt cgccagcaat cccgaatatg cggtagccgt cggcctcttg
    38641 gcgaaaggaa ctaagaattg cgcgttatat attcctccta aaccggagcc taagattgag
    38701 ccggtggttg agcctgaacc gacagtggaa ccgactccgg aaccggaacc cgtcaaggag
    38761 aagccgaaga aagagaagaa aaaaggtccc ggcttgttcg ggcggttgac aaaaggaatc
    38821 gatacctttg gtaaaaccct cttcgatgac gatgataacg agagtaaata acgtgatcta
    38881 cgaatgtaat aaaaccggaa gacaatggac gatacaatat taaattttaa ttatcctacg
    38941 gatactccca aaatcattaa ggtgattggt gttggaggcg gtggcggaaa cgctgttact
    39001 catatgtata aggagggcat acacgatgtt acattcgtgt tatgtaatac ggataatcaa
    39061 gccttgaacc gttcggatgt tcctatcaag ttattgctgg gacgtgagat cacgcaggga
    39121 ttgggcgcgg gcaataagcc ggaacgtgcg atgatggcgg ccgaggagag tctggacgat
    39181 cttcgaggta tgttgaacga cggtacgaag atggtattta ttaccgccgg tatgggtggt
    39241 ggtaccggta cgggtgccgc tccggttatc gctcgtatcg cgaaggatat gggaatattg
    39301 acggtaggta tcgtaaccat tcctttcttg ttcgagggtg agcgtaagat tatacaggcc
    39361 ttgaatggtg tggaggagat cgcgaagaac gtggatgcct tattggtgat caataacgag
    39421 cgtttgcgtg agatttattc ggacctttcc gtgatgaacg ctttcggcaa ggccgatgat
    39481 accttgacga tcgccgccaa gagtatcgcg gagatcatta cgcttccggg tattatcaac
    39541 ctcgacttcg ccgatgttaa caccacgatg aaagatggtg gtgtcgcttt gatgagtaat
    39601 ggttttggtg aaggagaagg acgtgttcgc caagcggtgg aagacgctct gaattctccg
    39661 ctattaagca acaacgacgt aaagaacgcc aagaaaatcc tgttcaacgt atatttcagc
    39721 gaggaagccg agttgcgcat ggaggagatg aacgacgtgc ataactttat gtccgagttc
    39781 aaccgtgata tagaggttat ctggggtact gccgtggata atacattagg taataaagtg
    39841 aaaatgacga tcctcgctac tggatttacg atggatgata ttccattgat cgctgataaa
    39901 cgcaggaatg aagccgctca gatgacggaa gaagaattgc gcttagaaga agagcgaatc
    39961 gagaaagagc gtaaggagcg tgatttgatt ggtaaatatt atggtgcttc cgcacaaaag
    40021 gcgggtcgtt ttacctctcg tgcgaaagcg gtagttttga ctcaggaaga gttggatgat
    40081 gatgccttga tcgctttgat agaggataat ccgacttata accgggatcc gaagatcgta
    40141 gcccgtgccc gttccaaagt agcgggagag gatattcaag tatcggctcc gacaacggcg
    40201 aagcaaccgg ctaaccaacc tcgccaagat tctcagcggg ggggtaaaca agtgatcagt
    40261 ttccgatagt taataatata ataaggatat ggatttattt gaacaagtca gtgaagacat
    40321 taaaaacgct atgaaggcga aagataaagt cgccttggag acattgagaa atgtaaagaa
    40381 atttttcttg gaagcgaaaa ccgctccggg agccaatgat acgctgatgg atgcggatgc
    40441 cttgaagatc atgcagaagt tggtgaaaca agggaaagat tccgctacga tttatgtgca
    40501 acagggccgt caagacctag cggatgttga gttggagcaa gtaaaagtga ttgagaaata
    40561 tttacctcaa caaatgtctg ccgaggaatt ggagaaagaa ttgaaagcta ttatcgctca
    40621 agtcggtgcc gctggcccga aagatatggg taagataatg ggtgtagcct caaaagcatt
    40681 ggcaggaaga gccgaaggac ggatgatttc cgagacggtt aagcgtttac ttaattaatt
    40741 gattcatacg aagaccgcac taagggcatt ctgacaatta ctcgttagaa tgcccttggt
    40801 acggttttct cgtatatacc ttttcctttg acaatttaat tctttagaaa accatgatta
    40861 cttttacatg ttgtctgata gcccttatcg ttggatattt tacgtatggt aaatttgtcg
    40921 agcgggtgtt tggcgtagat ccctcccggg ttactcccgc tttcacgaaa caagatggtg
    40981 tcgattatat acccttgcct acttggaaga ttttcatgat ccaatttttg aatatagcgg
    41041 gtctgggacc tattttcggc gctatcatgg gggctaaatt tggggtagct tctttccttt
    41101 ggatcgtatt gggaagtata tttgcgggcg ctacccatga tttcctatcg ggaatgcttt
    41161 cgttgcggca tgatggagaa agtcttcctg aattgatcgg acggtatctg gggaacaact
    41221 ttaagcaatt tatgcggggc tttacggtta tcttgatgat cttggtgggt gctgttttcg
    41281 tagctgggcc tgcagggttg ctggctaaac tgactccgga atatctagat gctacgttct
    41341 ggattatcgt cgtattcatt tattatatac tggctactct attacctgtt gataagatta
    41401 tcggaaagat ctatccatta ttcgccatcg ctttgctatt tatggccgta ggtatcttgg
    41461 ttatgttatt tattaaccag ccgccgttac ctgagattac ggatggactt agtaatacgc
    41521 atccgggagg cttgcctatt tttccgatca tgtttgttag tatcgcttgt ggcgctatct
    41581 ctggctttca tgctacccaa agtccattga tggcccgttg catgaaaagt gagaaatacg
    41641 cccgtcccgt attttacgga gcgatgatta ccgaaggtat cgtagccttg atctgggccg
    41701 ccgccgctac gtatttcttc cataataacg gaatggagga gaacaatgcc gctgtcgtag
    41761 tagacagtat cacaaaagag tggctgggcg ctgtcggagg tgtattagcg atactgggtg
    41821 tgatagcagc tccgattact tctggcgata cggctttccg ctcggctcgt ctgattgtcg
    41881 cagacttcct gcaaatggag caaaaaacgg tggtcaaacg tctgatgatc tgtattccca
    41941 tgtttatcgt tgcgatagga atcttattat atagtcaaaa agataaggat ggcttcgata
    42001 tgatctggcg ttatttcgca tggagtaacc agacgttggc agtatttacc ctatgggcct
    42061 taaccgtata tttggtacaa gcaaagaaat tatatgtgat aaccttgatt cccgccttat
    42121 tcatgacggc ggtatgttct acctatattt ttgtagctcc ggaagggttt ggtctttcct
    42181 ccggtttttc tcaacttttg gggctactag ttacattgat cgttttcggg atcttcttag
    42241 tctggaaaag aaagaaagta taaaaaaggc tggcttacat ttagccagcc ttttctgtcg
    42301 ttattgttca agtgaattaa agcacttgta tgccttcctc acgggcttgt tcctccccgg
    42361 aaggagtgat taatttataa cccttgccgt ggatgttgat gatctcgata cccggatcgt
    42421 ctttcaacaa tttacgtaat ttcgtgatat aaacgtccat gctacgagcg ttgaaatagt
    42481 tatcgtctac ccagattgtc ttcaaggcgt agttacgctc aaggatctca tttgcatggg
    42541 cgcacaacaa gcttaataat tcgcattcct tcgtagtaag tttcgtaacc ttgtcgccga
    42601 tagccaacgt ttgtttttgg gtatcgaaca agaagtttcc taacttgtag aaaggaatat
    42661 ctttcatctt cttacctttc acacggcgaa ggatagcctc gatacgaagc aatagctctt
    42721 ccatgctaaa cggttttgtc aagtagtcat ccgcaccgat cttgaatcct tccaagatgt
    42781 cttccttcat agtcttggct gtaaggaaga taatagggat atcaggattg atagagcgaa
    42841 tttcttgtgc caaggtgaaa ccatctttct ttggcatcat gacatccaac acacaaagat
    42901 cgtatttacc tttggtaaaa cctttgtatc cggcttctcc gtcagagaat aggtccgtta
    42961 catacccttt agcttgtaag tattctctta aaagcattcc taaattctca tcgtcttcac
    43021 aaaagaagat ctttagtttt tcttccataa ctaacttttt ataagaggta aagtaataat
    43081 aaattttgtt ccaatgtttc cggcaccact ttcagcacgg atcgtacctt tgtggtcctc
    43141 aataatttta cgtacgtaag cgagtccgag gccgaaccct ttcacgtcat gtacgttgcc
    43201 tgtcggtacg cggaagaaac ggtcgaatac ctttttcaga tattctttct tgataccgat
    43261 accattatct tccacggaga tcaacagctt tccgttctcg ttccaagtgc gtgccatcaa
    43321 tgtaagcgga acttccgggc ggcggtattt aaccgcattg tccatcaagt tgaacaatac
    43381 attggtgata tgcatttcat ccacatatat atccgattct gtagcttgca ggtctatatc
    43441 cattgtaccg ccgtacttct cgacctttaa aacgaaggtg ttagccacgt tcgctaccaa
    43501 atcatttgcg tcaatttctt tcaatttaag cgctgctttc tgtcgttcga acaaagacat
    43561 ctgtagcact ttctcgacca agaagctcaa tcgcttcgtc tcgtcgttga ttacgccgga
    43621 tatatgcttg aatacgtccg gactcttcgt tatatccgaa tccttcaaca tctgggcggc
    43681 gagcgagatc gtggataccg gtgtcttcaa ctcgtgcgtc atgttgttga taaagtcgtt
    43741 tttcatctcg gataacttct tctgacggaa tacgatgtaa atcgtgaaga cgaaggttat
    43801 caacaggatc aatgagaata taaccgatgg aacgatgaaa gtaatagagc ttgagatata
    43861 atcccctttc gtcggaaaat aaactctcag gtagtttagt ttcgatgggg gatcgttcgg
    43921 gaaaagcact tgggtgatca cgtcagaggc gatcggttgc ttttggaatt ctccgctctg
    43981 gtatactaca tttccatctt tgttaataac agaaaacaca aacggcaagt tcaaaccgtt
    44041 gttaataaat tctgttttta agtaattgtt cagcttttta aaatctatac gttcctcaat
    44101 cggctttaga ttcgcggtgt ataagatgtt gtaaatcacc tcctctatca gtccaccttg
    44161 gtactggtaa cgtcttttta gtgtcttctg taaatcttta gatgtgttta cgatgctgtt
    44221 ggcagactgc cgttttgaca aggaagagag cggctcgaac ttatgggcgc taaaactttg
    44281 catctctatt tgttgaacgg ttccattaga atccttgatc tgtaattggt atttctcatg
    44341 gttgatcact tgtcctaggc tttgggcatc cggggcattt tgatacatga aatttgtctc
    44401 atcccggttg atatcatcct cgaggtattt acgggtctca tccaattcca gattcttaga
    44461 tacttggcgc aggcttcttt tgacagtctc attgaactgt tcgctgcgtg tcttaagtat
    44521 aatgctcaca tagtttacct gtaggtataa taacccggcg aaggcaaaag ccataactac
    44581 cgcaagcaac caaattgtcg acttcctcat atcaatatct ttctcttaat attgcaacaa
    44641 ataacgtatg ttttagttta atatttacac aaaaaaggta aaaataatcc gtttaaaatg
    44701 ttaataatac tttgtgggca tagaggatgt atgctagcta agcattgaaa ctccgctgtt
    44761 aatgcactag ttagcgttat tttatcctaa gttttttata tattatccta agtaaaaaca
    44821 agtccggtgc gttctttgtt gcgcccggac tttataaagt ctccacttag gggattaaaa
    44881 tcgatgtccc ggaggaggac ccatcggacc tcttccccgt ccgcttctac ccggcgtttt
    44941 cacgtcgctg gcactggctc cgcctttgaa gatgctgaac cgatagatga agtgtaccat
    45001 gaaataactg cctagcgtgt tatattctga gtcttgtata tagctagcgg taacggaacg
    45061 ggagatattg cttcgttgtt gcaggatgtc gtagatcttg aaacggagcg tcccttggtt
    45121 attctttaag aaagacttgg aggctgaggc attccatagg acttcgttct gtttgaatcc
    45181 gtccccgtag ccagagttgg tagaccagtt cacgtcactc tctatcttga aattgagggg
    45241 cagatagatt gtcgtgtaac cgccggctcc gtaattgaag gtgttttggt tattttcctt
    45301 ttgcagggag ttgctggtgg cattgtaacg aatattcccg tttacgccca gatccagata
    45361 agaggagcgg aagtcgatac caccacgttc ggacaatatg agattccggt tcgtattctt
    45421 ctcctcgttg atatatccgt tgctattagc gaacgaggcc attgtcatgg agttgatgga
    45481 gaatttctta ttcttcaagg gggtattcaa catcatacgg acgttgccac tatagttgcc
    45541 atttacgttt ttgtaagtgg tggtctttac acctgtctct tggttataag aggtataact
    45601 tacgatatcg ttgatgatat aactaccgtt tgccatgatc ataaaggccc gttgtttctc
    45661 cggtgtgaac tgttggaaac gaataaatac gttgttcgta tagcggggat tcaaatccgg
    45721 gttaccgatc gtgatattcg tcgggtccga gatatccgct accggttgta attgagtcat
    45781 gctcggttgg ctggtacggc cattatacat gatacgaaga ttcgtacgct tatcgaacat
    45841 atagttgaat tgagccatcg gggagaggtt gaccacctta cgggttatct tggataaggt
    45901 cgtgtcgcca acgaaattct cgctgctgga ataggatggg tccagattca agccgatcgt
    45961 gtagttgaac tttgcccgtt gagacttgaa gctcaagctg gcccgctggc tgataaagtt
    46021 attgcgatag ctttggctgt aggcggaatc taatacatta tatataccat cagcgtcttg
    46081 gttgtaaaca ttcttcaagg cttcttgttt ccgttggctg atgctataag tggcttggat
    46141 gaaattatta tgcccgatcg gttctaccca cgatacgtag gcccggtaat tgaaaccttt
    46201 gttgtcgtaa cgtgagcgct ggtcgataat gctattcttc aaggcatcag tctggttgaa
    46261 ataaacgatg tcggaacggt tcatgccgtc actgtacgaa tcgctattgc ctccagaaag
    46321 ggtggcgctg aacacacgtc ctttgttatt cagcttacgg ctgaaatcga tgctggcatt
    46381 taggttgtac ccgttacttt ccgagtaatt actggatttg ttggtattga ccgtatcccg
    46441 ttcgttatcc aaggtggtag catcactgaa attgtcgttc atgctgtggc tgaagctgaa
    46501 actcgggcgg aagataagtt gagtcatcgt atccggtttc cattccaagc gaaagtctac
    46561 gccaaagtta tcgctcttcg tacggctcat cgcctcgcta ttatcatagg aggaactatc
    46621 tccgggaagg atattctgcc gatcactctt gctgcgagcg tcattgtcgg aatgggaata
    46681 acgagtattt cccccaagag ttagtttatc cggcttgaat tccttgctga agttcaaacc
    46741 tgcgtttccg gaagaggtga taccgctacc cgctccgaaa cctcctcgtc ggcctccacc
    46801 gcctcccata ccggagaaca ttgttgaggc tagatcggaa aagcccatat tattcgtgtt
    46861 attcgctccc cccatgaacg tgatctggtc attattcacg aaacgattga ccatggcgtt
    46921 gccttcatac cgatctttac ttccgtatcc accatatgcg ttgccaaacc aaccttgctt
    46981 catgccgggt ttcacggtta ggttgatgac ggtctcttcc tctccatcgt cgaagccggt
    47041 catttgggcc atatcgcttt tcttatcaag tacctgtaat ttatcgatca tcttggctgg
    47101 aagattcttg gaggccactt tcgggtcatc ggagaagaac tcctttccgt ccaccattac
    47161 ctttttcacc tcttttccat tgacggtgat cttgccttcg ctatctacct ccacaccggg
    47221 catctttttc aataaatcct ccaaaacgga gccttcggtt actttataag aatccgcatt
    47281 gtattccaca gtgtcgttgc gaacggtaac ctcgggtgcc ttacctataa ctacggcttc
    47341 tcccaactcg atcgctccgt cgcttaattc aagtttacct acgtttacgg ggtttttctt
    47401 tccggtgatt tgcaagggtt ggtacaatgg atcgtatccg atgaatgtga tgtgtagtaa
    47461 ataacttcct ttctttacgt ttttcaaggt aaaactacca ttacgggcgc tcaccacacc
    47521 tcgtaccatg gcactgtctt ttacgttcag caatcgtacc gttgcttgct cgatgggggt
    47581 atcactacct tgctcaacga cagatccggt aacattaaca ccgctttgct gtgcgaaagc
    47641 catcggtgaa aaaaggatca tcaacaacat caaaaggcac tttcccgatt tcataactat
    47701 atggattaca ttgtttacaa ttacgaaaag atagacatgg ttcattcaaa atagtttaat
    47761 ataactttta tggatttgat attattaaca atcgtgcagg cctttggatt tatggagagt
    47821 attcttagaa caagaacatt ataaaaggta aatagtcctt caacttaact cgcaatattt
    47881 tcaaggattg tgtaatccgg tattccacgg tttttataga aacccctaag gcctctgcga
    47941 tttggagatt agattgttct ccgaatcggc taagtttaaa tgtctcccgg taattctcag
    48001 gcaattcttc gattgctttc gtgatattct ctgtaagctc gtttacgaaa taggtatcag
    48061 gattctcaaa ttgatcttta atcttatcat aaatcaggct atgtactcgc tcatgataca
    48121 attgcctttt gatcgcattg aggcaacgat gcttaacagc cataaaaaga taggatttca
    48181 aggatatctc tacaaataag gaatttcggt tttcccatat aaataacatt agctcctgaa
    48241 taagttcttc ggcatcctca tcagaaacat attgggaagc atattcgcat agtggcgaat
    48301 aaaatttgat aaacatctgt ttaaaagcgt ctttacttcc taattgtatt tgttcaatta
    48361 aagtagaatc atccatagca ccttcttcat cctttctttt ctgtaagcaa agatatattt
    48421 tatcttggat attcaaggtt aaaattaggg taaccacatc gaaatatcac ttttaggaca
    48481 tccttatcac aagatatact tactttaccg atgaagtact acttacttta ctgatgaagt
    48541 atatatccta tggaaaagta ggtaagtcta aagtcttccg taaaaaaatg ctttttagtt
    48601 aagggtgtgt tcgttcagga ttgtcttagt tatagaaaca gataagaatg aaaactgaaa
    48661 atagacatat taatatccaa gagccggaag gtatgatgct tttacggtat ataaaggaca
    48721 cagcttccaa tgaggaaaaa tcttatattg aagcttggct ggaagcggat gaaaataata
    48781 agaggatctt attacagacc gcccgtatat attatgcgaa caatgcgatg gaacggatcg
    48841 ctagccgaaa tccattgatt gcctacgaaa agctggaaca acgattagca aaacggaccc
    48901 gtttatattg gctgaagagg ttctctgctg ctgcggcttg tataattgct atcattgggc
    48961 tatcaacctt attttcccat agaaaggttg attctgaatt tggagatcct caaattataa
    49021 cacttcaggc aaatgcggga gtccgtacac gctttaattt accggatggt actgttgttt
    49081 atctaaattc gggtagtgtt ttatcctatc cgatgtctta tgaccaaaaa gaaagaaaag
    49141 tatgtttatc aggagaagcc tattttaaag tcactcacaa cgaaaaacaa ccttttattg
    49201 tcagtacttc aggagatcag catagggtta gagttttagg cacggagttt aatatacaag
    49261 cttatgggga tgagaatata atttcgacta ctttagtgac gggctccgta aatctcgagg
    49321 tgaagaataa atcagggaat gtgagtcata ggacgttact accatccgaa aaagcgattt
    49381 gcaacttgga taaagaagaa atttctgtga tgaaaataaa tacgatctat gaaaccgcat
    49441 ggatggatgg caaactgatg ttcaaggata cgcctttacc tgaggctttg aaaaaattgt
    49501 catattacta taatgttgaa tttgtgattc aggatgcgga gattaaaagc tattgtttaa
    49561 ccggtatttt agataatagg ctgctatctc agacactaga ctatttgaga atatcttcaa
    49621 atattgatta tcgtatagaa gatatgaaga cagatgatag caaaggtact aaccgtactc
    49681 gggttatact ttggaaagga aaataaagaa aaatgtataa taattaaata atatggccta
    49741 tggaataaaa gaacaagaat gtagacttga tctatttaaa aaacatacgg gaaaatgtta
    49801 ccagcatctt cccatatgaa acaatttgat agaggtcttt aaaccgacta agaaatttat
    49861 tttttaatct taaatcaatt acaaaaatat gatgaataat ttatatttcc aacttgatgg
    49921 agataaatca gcgtttgtca ggttggtatc taaaatatca agaattatga agttgacctt
    49981 atttcttgta tgtttatcaa ttagtatgtc atttgctatg acaacaaatg ctcaaagcac
    50041 ctcactttct tttaaagcga cagatcaatc tataaaagaa gttttggaac tgattgaaag
    50101 tcaaaccgat tttcacttct tttataatag taaattagtt gatatcaatc aagtaatatc
    50161 tgttgatata aaggataaag acgtgttcac tacattagat catatattta agaattcgaa
    50221 tatacgatat aaaatagtag gaaaagatgt gattctatca gtaaaaggca gtaagtctga
    50281 tcaagatgaa aagacagtaa caggtactgt tattgatgag gcgggggagc ctattattgg
    50341 tgcaaatatt gtagagaagg gtaaagcaaa tggaactatg tctgatttga atggtcattt
    50401 ctctattgta gtgtcttccg atgcggtgct ccagatttct tatattggat tttctcttca
    50461 tgaagaagcc gtgaaaaata aaaatgtact tcaggtcatt atgaaagagg atacacaaaa
    50521 attagatgag gttgttgttg ttggttatgg ctcagttgac aaaaaagagt tgacttctgc
    50581 tgtaaccgct gtttctagta aagacttttt acaaggagca tttacaagtc cgttgtcaat
    50641 gatcgatgga aaagtatcag gcgttaatgt ctcgaatgcg gcagcggcag atcctaactc
    50701 ttctcctaat atccagatgc gaggtgcttc ttccatagag gcagggaatt cgccattggt
    50761 tattatagac ggaatgccgg gtgcagattt aagaagtgtc gctaaccaag atattgaatc
    50821 aattacaata ttgaaagatg gttcggctgc agcgatttat ggttcacgtg cggcgaatgg
    50881 agttattttg gtgcaaacaa aaaagggaaa ggctggaaaa gtttctatat cttatgatgg
    50941 ctatatcgat catgatatgg tagctaatca accaaaagta ctttctgtag atgagtttct
    51001 tgcgcatgaa agagatgtag attttggtca tcgggtggat tggtatgaca aattgttgaa
    51061 taagagtaat ctgggtcaaa gtcattattt agctgtttca ggaggaagtg aaaatttgac
    51121 ctttagagct tctgccaatt ataagaagaa agatggcttg gatatagcgt cttctagaaa
    51181 agagtatgga gttagaatgg gattcaccgc aaagacatta gaaggtctgt tagagattca
    51241 aggaaacttg tccacgcgag ttatcaatga ggaatatgtg gattatggcg tatttcagca
    51301 agcggtaaaa ttgaatccga ctcatccatt gatggatgaa aaagatcctt ctaaatatag
    51361 tactctgtat gggtttgata cctataatcc tgtaggatgg ttgaaagaca aggaggatgg
    51421 aggtgataga cagttttccc ttgctgattt taaaatgaaa ctaaatattt taccgacgct
    51481 aaatactgaa ttatctctag ctagacaggg gcaagagtat tttaagcgta tatatgttaa
    51541 ttcaaatcat aaggaatcta tagataatat gcgttccgga cgaggaactc tgcaggaaga
    51601 aaattatacg gattatacat tggaatggat cggtaattat tttacgacaa ttgacaagca
    51661 tacaattaaa ttaatggctg gatattcgta tcaagagttt aatcatcgta gtttttcttc
    51721 agagaatgca aattttcctt cggatgcgat gtcctataac aatctggaag ctggagattg
    51781 gaatatggca gcaggtcgtt taggggtatc ttcgttgaaa gaaaaagaaa agacaatagg
    51841 ttttcctgcg cgattgattt ataactatga tgatacttac tatttgacgg cttctgttag
    51901 atatgaagga aatagtaaat ttggggcaaa tcataaatgg ggatggttcc ctgcagcctc
    51961 tgcagcatgg cgaatgtcaa gtttgcctgc tattaaaaat attgaggcca tcaatgattt
    52021 aaaactccgt ttttcatatg gagttacagg acgctctggt ttcccaaagt attcagcgtt
    52081 ggctcgttat gagcaaggtg ggtattggct agacgataat ggacaatgga cccaagcgtg
    52141 gggacctacg aataatccta atcctgattt acattgggaa aagcagatat cttataactt
    52201 gggtgtggat ttttctcttt taaagaataa gttatcaggt agtttggatg cctatgtaaa
    52261 acaaggtaaa gaagtaattt ctaattatga cgctccacta ccccctttta tgtttgatca
    52321 gatatttaca aatgtagctt ctactagttc aaaaggtttg gaactgactt taaattggga
    52381 tgttgtaaac atgaaagatt ttagttattc gactaatcta gttgcttctt ttacgaaatc
    52441 taaactggat aaattctcga atggtacata tcagaaagga tatatggatc gatatttact
    52501 gccagctccc ggaaatcccg gctatgccca acgcttacaa gacggagtgg aaattggttc
    52561 tttttatggc ttaagatatg cgggagttga tgataatggc aatatgttgg tttggaaaga
    52621 cgctaaaatt ggaggagaaa aaatactcgc taatggtgaa gctagtgata cagacaaaga
    52681 ttatattggc catggaacac ctagatattc tttgtcttgg gggaatacat ttcgatataa
    52741 aggatttgat ttaagtctat atttccaagg gcgctttgac tatcaaatat tgaatatgta
    52801 tcaaatgtat tatggattag ttgctgaacc gggtatgaat ttattggaag atgcttatgg
    52861 aaagaatggg catattaagt ctggaaaagt gatgtgtgat tattttttgg aggatggaga
    52921 ttattttagg ttggataaca taactttagg atggactcca aaattagata caaagtggat
    52981 tagcaattta cgggtatatg cgacagttaa aaatgcgttt actattacga aatattcagt
    53041 aatggatccg acatctgtgg atataaatgg tctagaacca ggtattagcg gtctaaatgt
    53101 gtatcctatt gccagatcat tcacatttgg aattcaaatt tcatattaat cttaatttca
    53161 tttattatga agaagtttaa atatataata gttcttttcg tgatgggatt aatctcattt
    53221 tcttgtacag atttagatga agagattttt agtgagatta caacggataa ctattatcaa
    53281 aatagtaata atatttatgc ggcgttggtg aataactatg ctaaggcttt tagtacgggt
    53341 tggtctgatg ctcgatactt tttacaggaa gttactgccg accagttaat gattccgaca
    53401 agaggaaaac atggttataa tggtggggag tatgttcgtt tgcatgagca taaatggact
    53461 gtggaggaga atttcgtata taatggttgg gctgctcctt ttcaaggtat agcattatgt
    53521 aataatacat tgtctgattt tgaaaatcta gatttctcta cgtttaaatt gacggaagaa
    53581 acgaaaaatg aatatatagc cgaattaaga gctcttcggg tttggaatta tatgttttta
    53641 atagatttct ttaggcatgt accaattgtt acagatatag aagaagtgaa ggcccaatct
    53701 acacccctag aagtatttaa ctttatggag tcagagcttt tagctatatt accggactta
    53761 cctaaaaata ggggggtatc taggtttgat caagcaggag tagcttctat acttgtccgt
    53821 ttatacttga atgcggaaaa atggataggt atctcaaaat atgatgaatg tgagcaaatg
    53881 gctcaggcta tattagatgg aaaatatgga gaatatagta ttgaccctga ttatagaggc
    53941 ccgttccgct cggggataaa cggttataga tctaaagaga atattatgga atttgcgatt
    54001 aagaaaaatt attttgaggc atcttggcta tataatatgt ggatgcacta tcaagatcgt
    54061 tattccttgg ataatgactg gcaaggttgg aatggaggta atttagcacc gtctcgggac
    54121 ttatatggaa atttgtacca agataaatta ggtatgccgt ttgaaaaatt cccggatgaa
    54181 gatatccgaa agaaagcttt tagagttatt tcaaatgatg gagattatga gggctttttc
    54241 ttgatgggaa ctcaatataa atttgattat gaaaaagggt atggatttac agatgaagta
    54301 ataactggta cggaagaata taatggtaaa cctctagttt atgtggatca agttggacgc
    54361 ttttcggagg gagagactgg tttagccaaa ggctctcatg taatttacgg agaagagaat
    54421 acgggatatc gtttgataaa attcccttgg ttacctcaat cgaaagattt gttccaaatg
    54481 aactctattc cagagatcag attggcagag atttattatt cgttagctga atgtaaatat
    54541 agatcagggg ataagatagg ggctgctcgg ttgctggatg cggttaggaa acgttattat
    54601 aaagcggaag attggtctaa atttagttac gaatctaata tctcgaaatt aactgatgat
    54661 gaatttgtcg atgaattagg tcgtgagttc ataggagagc gtcatcgtcg tattgattta
    54721 atacgatgga atcgttttag tgaaggtgcg tggtgggata aaactccgga tgcgacgaat
    54781 caagacgtat ttccgatccc ttatcgtgct ttgaatgcga atcctttgtt aaaacaaaca
    54841 acagctggct tttaataaat agaatcgata tatgaaacag tttataaatg taaaaagagt
    54901 atttaccgta ttgattatac ttttgttatt aatatcgtgt agggtcgaaa ctgattatag
    54961 accattattt gacaaagatt tatcaaatgc tgattatgat agttcggttt ggacctttaa
    55021 aaatggcata cttactgcca ctgccgatca atctatttgg acgaaggtgc agtatgaaaa
    55081 ttttatcttg gatttagaat tcaagacaga tgtgaataca aatagtgggg ttgtgattta
    55141 ttgtacggat aagggtaatt ggatcccatc ttccattgag attcaaatag cggatgatca
    55201 tcatcctgaa tggcaatcat atccagaata ttggcgttgt ggttctattt atggacataa
    55261 aggagcaaat gaacaattgg tcgtgaagaa accgggagaa tggaaccgca tgattgtcac
    55321 tgctaaaggt cagcagatag atatcgaatt gaatgggaaa catattgttt cggctaattt
    55381 agcagattgg acttctggaa caacaaatcc agatggaaca gagattccgg aatggctacc
    55441 aatcccgtat gcgaatatgc caacaaaagg ttatattggt ttgcaaggga aacatggaga
    55501 atctaatatt tggtttagga atattcaact gaaacaactt taaaatcatc attattatga
    55561 gacatatatc aagaagagat tttttgaaga caggagcttt agcagcaggt ttaacgatcg
    55621 taccaaattc tgttttaggt aaaacgcatg ggtttacttc accaagtgat aaattgaata
    55681 ttgctggagt tggtgtcggg ggaatgggcc gtggtaattt acggaatatg agtacagaga
    55741 atattgtggc tttatgtgat gtagattgga gatatgcaga gaagactttc aatgattatc
    55801 caaaagcaaa aaaatttaaa gattggcgtg ttatgttcga tgagttcgga aaatcaattg
    55861 atgcgatatt ggttgctact ccagaccata cacatgcggg agttactgct catgctatta
    55921 cattagggaa gcattgttat actcaaaaac ctttaaccca ttctgtctat gaatctcgtt
    55981 tactagcaaa actcgctaaa aaatataaag tagcgacaca aatgggtaat caaggaaatt
    56041 cttttgattg gtgtcgtcaa ataacagagt ggattcaatc cggtgttatt ggggaagtat
    56101 atgaagttca ttgttggaca gatcgtccaa tttggcctca aggattgatg caacctagcg
    56161 ataatctgaa atgcccgaag actcttgatt gggatttgtt tattgggcca gcgcaaaaaa
    56221 gaccatataa tccagtttat acgccttgga attggcgagg atggtgggat tttggaacgg
    56281 gtgctttagg agatatggct tgccatatta tggacccact ttattgggca cttgatttga
    56341 agtatccgat aagtgtgata ggtagttcaa ccttgagcaa tttatattcg ccacctcatg
    56401 cacaagttgt aacttatacg tttccagctc gtcccccaaa aggaaacaca aaaatgcccg
    56461 aggttaaggt atattggtat gatggaggtt taatgcctcc tcgtccagag gaattaaaag
    56521 atggacaaat gatgggagat gaaaatggtg gtattatttt tattgggaca aaagggaaaa
    56581 tcatgactgg ctgttatgga atgaatccaa ctttattgcc cgtatctgat atggaacatt
    56641 ttaatcaacc taagccttca ataccaagag ttaaaggtgg taatggcaat atttgggcta
    56701 cgaatgccca tgagcaagat tggattcgtg cttgtaaaga atctccagaa aaccgagtag
    56761 aatcatcttc aaatttccaa ttctccggac cttttaatga aatggtagta atgggagttc
    56821 ttgcggtacg tctttctggt cttcatggac tacatagaga attgttatgg gatggagaga
    56881 atatgaaatt taccaatata tctcctactg acacaattaa gattgtaaca gttgatgatt
    56941 ttaaagttgt tgatggtgat cctcgttttg atcgtcgttt tgcggacttt aatgctcttg
    57001 atgttgcgaa tgagtggatt aagcatactt ataataatgg ttttagttta cctagtatgc
    57061 cattctgaga acatagaaag gtcgtgaact actgttggat gtcatttagt taaagagtat
    57121 ccgtaataga tagaggttat ttcttttcaa gaggaaataa cctcttctta tttttttatt
    57181 ttatatttgt tcggtcaata tgtgctagag gagatggatg tagaacggat atacctagaa
    57241 cgattacgaa gcggttcata cagagacttt acgaaactgt atgaatcata cgcttcacgc
    57301 ttatatgcgt tcgcattgca cttgactcat tctgatgctc ttgcaaaaga tattgtacaa
    57361 gagactttta tcaaagtgtg ggtgcggaga gaacagattg atttagatat gtctttcagt
    57421 gctttcctat ttacgatggc caagaaccaa ttattgaatg agtttcgtag gcaggcaaat
    57481 agtccacttt ttttggaaga tgttgtactg aatgagtctg gagatggaga ggaaacagcg
    57541 attgaacgta aattatcttt tgaggaattt aaccatagac tggaaatagc gaaacaaaag
    57601 ttgacacctc gccaacgaga actgtttgag ttaaataagg aacaaggtat aactataaca
    57661 gaaatagcgg ctaaagcctt tatttcagaa caatctgtgc gtaaccagtt atcgcaagcc
    57721 ttacatgttt taagaaagga gctcggtaag tatgctttgc tgttctctct tttctttatc
    57781 ggataaataa aattgaaaaa ataatattct tatgttttat aacatctaaa aagacatgtt
    57841 ataaattaac ggctcatgtg tataccttat aaaaagggta ttatgcagga atcacataca
    57901 tattatttgc tctcaaagta catggatcat acgatctcta cggaagagtt gaaaacacta
    57961 cggcttttgg ttaatttgtc tgatgatgat gaattatcgt tgtcattgtc tcttttatgg
    58021 gaaaatgggc gaccctttga agaggttgat gagagaatca tacgagatat gttcagcggg
    58081 attcaaaatc gaacgagaaa agaacgattc gttatggtgt ttaggaaact ggctcgtatc
    58141 gccgcaatac tattaatacc tttattaagt gtattgtctg gttatttata tttcaatcca
    58201 gtcaatcagg aggagggtat tggtaattta gtggttcatg ccgatagagg ggaaagatcg
    58261 ggggtgactt taccggatgg aacacaagta aaactaaatg cggaatcgag cttaagttac
    58321 actcacgatt tcggtcgaga gcttcgacag gttaatttag agggagaggc ctattttgag
    58381 gtgactcgga atgaggataa acctttcgtg gtacatacaa aatatctgga tatagaagtg
    58441 ttgggcacaa gttttaatgt gtattcgtat gaacgggaga atgtcatgga aatggccttg
    58501 atatcgggac ggatcaagat acagacttgt tcagagcctt ctcgtgtcgt ttatctaaaa
    58561 ccgaatgaaa aagcattgtt caataaagaa tcgggtatta taaccgtgga gaaaacagat
    58621 aatcgatttg aaacggcatg gttaagagga gatctcgttt tccgatcaac gacattaagt
    58681 gatgtcttgg ctaaactaga gcgtagatat ggcgtgaata tccatttgaa tgattcttct
    58741 ttagcgaatg acttatttac cggaaatttt gatagtgaat atatcgtaga ggtaatggac
    58801 cttttagaga ggcattatga ctttacatat gatgtacgag gagatgatat ctttatacat
    58861 ccttgagcga gtgaaaataa aaatgtacaa ccttaaatca gttcttatgc gacaagattc
    58921 ttcataataa aaacggaacc gaaaaatggt cgagattttc cggttcccca attaatactc
    58981 catttacgag aatggcgatt aggccataaa acggattgta tcaatttaaa aaaataatat
    59041 atgttcaaaa gtagaaaaaa tcaatgtagc tatataattt ttttggctct atttctgttt
    59101 tttaatccta ttttggtatt agctcagaca ggaagtgtca ctctttccat gaagaatgct
    59161 acattaaagc aattttttga ggctgtagag aagcaaacca catatatatt ctcttatcgg
    59221 gatgctatag tggaaggaaa gaaggaggta actttaaacg tgacgaatca gccgattcag
    59281 cgtttgttgg atgatgtatt gcatcaaagg gacttgcaat atacgatgac aggccattca
    59341 attgtcgtaa ctttaaagac tgcaggtaaa gtaaagcagg tatctggtac tgtggtggat
    59401 agtaacggcg aaccgattat cggagcgaat gttgttgaga aagggactac gaatggaacg
    59461 gtaacggata tctcgggaaa tttctcatta aatatagatg ataccggtat tttacagatc
    59521 tcgtatattg ggtttaatac tcaagatgta gcagtgaacg gaaaatcaag tttaatgata
    59581 aacttgaagg aagatactca aaaactggat gaggtagtcg ttgttggtta tggcgtgcag
    59641 aagaagtcga atgtaacggg atctgtggct tctattaaga cggatgattt taatgattta
    59701 aatatggatg tgtcgcatgt tattcaagga cgtgtggctg gtgtcaatgt ttccaatggg
    59761 aacattatca ttcgtggagc ggcttctatc aatggcgcgg atccgttgtg gatcgtggat
    59821 ggagtgccgg gtagcgctcc taattttaat gatatagaat ctatcgagat cttgaaggat
    59881 gcggcttcta ctgctattta tggtgcccgg ggagcaggtg gtgtgatcct tgtaaccact
    59941 aaaaaaggaa agatagggaa actttctatt aatgcgagag taaactttgg aatagagact
    60001 ccgatcgatt tgccggatat gctgcatacc gcagacttta ttgaccggaa actggcggca
    60061 ggcttcccta ataatcccaa ttccggctgg gataatcccg cttcgctacc agatacagac
    60121 tgggaagatc tggtttggcg taatgctttt aggcaaaact attttttaca gatgacaggt
    60181 ggtaatgaga aaactacatt taatatgtct gcggagttct acaagaatca gtttatcgaa
    60241 cgttattcat ttgaggatgc gggtaatttt cgtgtggcta gccagacaaa tataagtaaa
    60301 cgtgtgaaat tttctgagat cctgactgtt ggttttaata atacggatcc ccatttgtat
    60361 gggcagacga ataatgatta tgtttattac cgccaagttc ctacgatggt gccttatgat
    60421 aataccaacg aagctggtgg aggttggggg aaacatccgg caggtggtta ctacgaggga
    60481 cctaatcatg tggctacact aatgtcgcat catgcgaatg aacgtaggtt ttgggcccgg
    60541 gcaaatgcga ttttggattg ggagattatc aatgatttaa aattccaagc gaatttctct
    60601 gccaattttg actcccatgc gaataatttg ttcttagaat catggaattt gggatctttg
    60661 tctcaacagg attattactc gaaagattat ggctccggtt atgatttacg tatgttatat
    60721 acattgactt atgatcatac ttttggggag aaacactatg taaaaggtat ggttggctac
    60781 gaggcttatc gggcgacggc ttcttcggca ggtggttgga aaaacggctt cttggttcag
    60841 ccttcggatg atattagttt aggtacggga gataaagatg tatccggaac gaaaacggaa
    60901 ggtcgtagtt tatcccagtt cgctcgtgta aactatgctt atgatgacag gtatttgcta
    60961 gaggctagta ttcgtcggga tggttatgat aactttggtc cagagaatcg gtttggtgtg
    61021 tttccttcgg cttctgttgg ttggaatgtg ggaaaagaga gctttgtaaa ggataatata
    61081 acatggatgt ctcaattaaa actgagagga agttatggta aaattggtaa caatacaatt
    61141 cctcaattct tgtatgaacc ttcttttacg aataattatc tatattattc atatgatggg
    61201 caaaatacgc agagaggatt ctggtattca aatgttgcga atgctacgat taaatgggaa
    61261 gacgtggccc aatggaatat aggtgttgac gcaagttttc tggataatcg cttgaatacg
    61321 acaatcgagt attatgataa gaaaacttcc gatatgctgt attcagtagg tgtgccacct
    61381 tctgccgggc cttcttcgga accatttagc gagacctctt cttatcgggc taatatcgga
    61441 aagataagca atagaggttt cgaatggatg gttcaatgga gggattccta taaagatttc
    61501 aggtatgacg tggcttttac gttgtctacc aacaagaaca aagtggtaaa gttaagtgac
    61561 caagtgaatc cgatcatttg ggctggaagc gatgcggctt tgaatagttc tatttatcgt
    61621 acggaaaatg ggcaaccgat gggacagatg tatgggtatg tagtggatgg cattattcaa
    61681 gaccaagcgg aaatcgatgc cttaaacgct caatctccgg atggattgta ccaacaagca
    61741 ggtacggctc cgggtgattt gaaatataag gatttaaatg gagacggaaa ggtgacgaat
    61801 gaggataaga catatatcgg taatccttgg ccggatttga tgtatggatt gaatataaat
    61861 ttgtcatgga aaggctttga tttaagtatg ggctggttag gaaacgcagg tgttgatgtc
    61921 tttaatagcg ctaagcttta tgaaagaagt ttctatggcg actataatac gacttataag
    61981 gtatatgagg cgtggagtcc gacgaaccgg gctacttcac atcctcgagt aacgaaagag
    62041 gatccgaatg gaaacttcaa gaatgtctcc tcttattttg tggaggatgg ttctttcttt
    62101 aaattgaaga atttacattt cggctataat ttaccgaaat caatactttc tcatttgaag
    62161 atagaaggtt tgaagtttta tattaactgc gataatttat ttattatcac aaagttccaa
    62221 ggagatcctg aattgggtgg tggatatttg gaacgaaata tgtattctgt gaaacgggct
    62281 ccctccaccc gcaccattat gggcggttta agtttaaccc tctaaattaa taggaagatg
    62341 aagaaattag ttatattatt agctgctgcg ttaactttta atagttgttc ggatagtttt
    62401 ctggatttat caaatcccag tgcgttatct ccaagtgtct accctaaatc tatggcggat
    62461 atggagacta tcgtaacttc agtttatgcg aatatggtcg ctgtgccttt gtatggaaaa
    62521 agggttatgg cgaaagggac attctgtgtg gatcatacgg tagatatggc ttggactggt
    62581 gacgccaact ggaaccagtt ggcgaccaat caagtgactt ctgataatgc ttacattggg
    62641 acgttatgga ttggttatta taaaatgatt tcttgtgcga ataccgtatt ggagcaattg
    62701 gaaagaatcg acaaggagaa gtttacggat gcggatttag caagactttc gcagatgaag
    62761 ggagaagctt tgttttggag aggttgggca caccaacagt tagtagcgtt ttttggggag
    62821 ggatatcctt gcaacgggga tggcgataaa aaaggtgtac ctgttcgttt acaggtagca
    62881 tcgactccag atatgctaaa tatagaacgt agcacggtgg ccgaggttta cgatcagatc
    62941 ttgaaagatt atgaggcagc caaacttttg ctacctgccg tatgggaaga gcgggcggac
    63001 tatccacgtc caacctctgt tgccgttgct agttacatcg ggcaagcgaa tttgtatatg
    63061 ggtaattatg atgcggcaaa gaaagcgttg aaagaggtta ttgattcttc cggaaaagaa
    63121 ttgctccctt tcaatgaata tgcgaagatg tttaatgagg atcaggagaa atttaataga
    63181 gaatcgatct tagagattaa tttccgtaat ggggatactt ccggatattt ttggtatgga
    63241 gaaggttctc aatatggatt gatcgctgcc ttatgtttcc agaacgcaag tggagatgtt
    63301 gaggcggccg gttggggtaa tattttcttt catgatgcga atattaaacg ttttaatgga
    63361 gatcctcgtc tggatatcgc cgctttgcgt ccgggaactc ctgttattat gaatggacag
    63421 cagacgcagg ttctgaaata taaggatacg gaggctgaca ttcaaggttg gagcatgcga
    63481 aaatacaatc cgttgaaaag tacggtgaat gagttgaatt taggggttgg tattaatatg
    63541 tatttgatgc gtttggcgga tgtatatttg atgtatgcgg aagcttgtca ggctacggga
    63601 gatgaggtaa atgcccggaa ctatatgaat ctggtaagaa gaagagctta taatggagat
    63661 agttcccatg atataacggc tagtggagaa gctttgagag atgcgattcg ggaggaacgt
    63721 ttcatggagt tctgcggtga gggcgtacaa cattggcaag atgtttgccg ctggaaggtc
    63781 ttggatgagg agattagccg ttggtatgga aagacacgtg ttggtaatcc gcattatgat
    63841 gcgaaagatt tgtatttccc gatacccaag gttgaaatgg agaataatcc gaatatgaca
    63901 caaagcatag gttacgagaa cgagtagata taacttgttg aaaagttcat caaagaaaag
    63961 gaataggata gttctcttgg gatcgctaat cctattcttt ttttattcct ttatgatcat
    64021 attaaatctt attgaataat gaagatgata gatgtatcga aagtaagagt ctttcggggg
    64081 agtctctttg tattgcttat gctctttatg cagataggtt gggcctcaaa tgatgatagc
    64141 acctataata tcgtggattt tggagctaaa ggagatggaa taacagacaa tacccagttc
    64201 atcaacagga caatagaagc ttgttccttg agagggggag gaacggttat cattccggag
    64261 ggaacgtttt tgacaggaag tattctgctg aaaagtaaag taaacttatt cttagaaagt
    64321 aatgccgtag tgaaaggcat aaataatctg gaaaagtacc gttctatatc cgatcttaat
    64381 caagatgagg cttattataa agtaaaaccc cggaattgga acaaggcatt gcttttagga
    64441 gatcaagttg aaggtgtgtc aattacagga gagggggtaa tcgatggtgc ccatattcaa
    64501 gataaaaaag gtgaagaagg gatgagaggc cctcatattc tctttttgtc gagatcgaaa
    64561 gggattaaga tatcgggagt taaactacga agagcatcga actatgcttt tatgagttat
    64621 gatattgaaa gggcttcttt cgataatctt ttagtggagg aaggatggga tgggattcat
    64681 attcgtggcg gaaaagatat ccgtatccga aattgccgtt tttatacggg tgatgatgct
    64741 gttgcgggtg ggctatggaa gaatatggta atagagaatt gctatatgaa ctcatcgtgc
    64801 aatgggataa ggttgataat gccggctact ggtttaaaga tcgttgattg tgaatttaga
    64861 ggtccgggaa aatatccaca tcggacttcc ggtgaacaaa aacgtaggaa tatgctttct
    64921 gggatattgc tccaaccggg cgcatggttc cctgcgtttg gggaagtaaa ggatatattg
    64981 atatctagct gttcttttga tcaattggat aatccgtttc tagtcacatt gaatgagggg
    65041 aaccggggag agcggatctg tctggagcat ataagaggta cacgtttaat gaaagcggcc
    65101 gcctcggtag agagttgggg agatagtagt ttgaaagatg tccggctttc ggatgtttcc
    65161 ttatcgtatg ttggaaacaa agatcaagaa atagtaggac gtactccctc gaagccattg
    65221 accgattatc gtgcgctccc ttgctggggg ctttaccttc ataatttaga tcgagtgatt
    65281 ttacggaatg ttcggttaga ttgtgagaat gggaaagttg gcccagcctc ttgtttcgat
    65341 aatgtggggt ccgtggagat ttataatgta agtttttaat cttaaaaaga attagtatgc
    65401 gaaaatatct tttgttttgt ctagcttttt gtgtattggg ttgtttggct caagatttga
    65461 ttgtccgtcc gaacgatcct attatttata agaaagaggg cggtgccttt ttatggctgg
    65521 gggatacggc ttgggagtta tttcatgtat tggataagga ggagatcgtt cattatctgg
    65581 ataaccggca agaaaagggc tttacggtaa tacaggctgt tatcttatct gaactggatg
    65641 gtttggataa accgaatgcg tatggatatt tgcccttggt tgataaagac cctacccaaa
    65701 tcacggaagg gtactttgag ttggtggatt ttgtgattcg agaggccggc aaacgaggaa
    65761 tgtatatagg gcttctacct acttgggcaa acaatgtggt agagaaagac ggaaatccag
    65821 cattgtttaa tccagataat gcgtatacat acgggaaaat actgggaacc cgatataaaa
    65881 atgaagctgt aatatggatt cttggtggtg atagaaatgt ggttacggat aaggagttcg
    65941 agatctggca atctatggcg aaaggaattc aggagggaaa tggaggaaca caactaatgt
    66001 cctatcatcc gacgggagag atttcctcgc attattggtt ccacaatgag tcttggctat
    66061 cattcaatat tctccaaagc gggcattacc gccggatgga tccggtatat cgtttttcgg
    66121 gtatgtatgc tcaattgaac ccgattaaac cgtttgtaaa cgcggaacct tcatacgagg
    66181 acataccggt tcttttctgg gaatattttg attatgctaa gttcgggaag aaaaaggagg
    66241 acataatagg tgataacgga ttgattaagg atacgactta ttttacggat ggaatttacg
    66301 atgactatga tattcgtatg caggcttatt ggacttattt ctctggagct gccggatata
    66361 catatgggaa taacgctatt tggcaaatgt ataagccggg tggtaaatat catgtaccat
    66421 gccttacgtt ttgggatggt gcgttggata ggccgggagc cgaatgtatg cgctatgtaa
    66481 agtctttgtt tacgatgtat ccgttagatc gtttccgtcc ggatctatcc gtcctgttcg
    66541 gaattaatta caatgacgca agctatatca ctcccgtttt agcaaaagat aagactttta
    66601 ttttagttta tttgagtcaa gggcaggatg taagaataca aatgagtaaa ttgcgatctt
    66661 taggtaaagc ttattggttc aatccgagga atggggcgag aaccttgatc ggaccggtcg
    66721 agaataaggg aattcgtaca ttcaatgcgc ccggagaagc gggagagagg ggaaatgatt
    66781 ggatcttaat tttggaggcg gatgataggt agacgatgta taaattttaa ataataaaag
    66841 tcattatgaa gaagatcaat gttttgctgt tagccttttt gctgttaagt ttttgggcga
    66901 atgcccagca gtatcctttt aacgggttgg atatgaatat gggaaacctt tctcgtttgt
    66961 cgaatgcgca gagtcgttcg atcagtccgg agaattttac gggggagaaa gggaaaggag
    67021 cgatggctga tcccgtgaga gataaggatg tccggaataa ggcgaatgcg gccggcccag
    67081 cgaaagattt ggggaaaggc tggaaagtaa atccttttat tatcgtgaaa ccgggggaga
    67141 cagttaccat cgcggagatt gatggcccgg gggctatcca gcagatatgg atgactccca
    67201 ctggcaactg gcgattctcg atactccgta tgtattggga cgacgagaaa gagccttcgg
    67261 ttgaatgtcc ggtcggggat ttcttcgcca gtgcttttaa tgagtatgcc caactatctt
    67321 cgttagcggt ctgtgtaaac cccgggagcg ctttcaattg ctactggaag atgccgttcc
    67381 gtaagaaagc acgcataaca ttggagaata ttaacaatgc ggaagagatg cgtttgtatt
    67441 accaaattaa ttataccttg acggaagtgc cggaggatga gggatatttc catgcacagt
    67501 tccgtcgttc caacccgaca caaggctcta gccatacgtt ggtggatgga atcaagggaa
    67561 agggacaata tgtcggaact tatttggctt ggcgtgtcaa tgataactgt tggtggggtg
    67621 aaggagagat caagttctat atggatggcg acaaggaata cccgacaatc tgtggaacag
    67681 gtacggagga ttatttctgc ggttcgtata acttcgagaa tcagaaaaca catcagtacc
    67741 aagaattcac cactccttat gcgggaatgc accaagtgat ccgtccggat ggcctatatc
    67801 gggctgttac ggcgttcggc ttgtatcgct ggcatatctt ggacccggtt cgttttgaaa
    67861 aggatctgaa ggttacgatt caagatttgg gttggcggca cgacggtagg tataataacc
    67921 agaagtcgga tatctcatcg actactttct ggtatcaggc ggaaccacac gctaaattcc
    67981 cggcattacc cagtaaggat gatttggaga ttccgagatg gtaaatggcc tgtggtaaga
    68041 tgttaaatgt tatttccgat taaacctttc ctttttatcg atgtctattc tttcgaagcg
    68101 cttcataaac aggtaattta taataaaagt aataagtagt agtttatgaa aaaggtaata
    68161 ggattgtgtt tggttgtatt gttgagttca acttctgtgt tcgctcgtga gaacaggcgt
    68221 atggacaagc gtaagatgga tccgtccgca cgttgcgaga agatgatcgc cgacttgaag
    68281 ctggatgaga aacaagcggt ggagttccgt aaacttcaaa aagagtatat ggaaaaggct
    68341 caaaaagaac gtgaggcgat gaaggctgag cgtgagaagc aacgggaaaa gatgttggcc
    68401 atgcgtgagg ataagaacgc ccagatgaaa aaaatattga cggaggaaca atacaaacaa
    68461 tatctggaaa aacagcagcc taaagggaat aaacatggca gaaaacatct aggtaacgga
    68521 cgtagataaa gaagtctata gatagataaa atggccgggg tagcgattat cccggccatt
    68581 ttagttctaa tcggctgctt caaccacata ccaagtatat ccgttggcag ggattttaac
    68641 cgtaagctcc accgtatagt cccggttcag tttgtaggtg acaggctttt gctctttttc
    68701 ccggatgcgg gctgtttgtg tcaggccggt ataatagagt ggaatatgga tcgtacgggt
    68761 gatctcttga tgggtcggat tgaagaacat ggctagacct ttctccttct tgtgaggatt
    68821 gacgtgtatg aacccgtccc agtctcgtgc gtccggccgg cgtaagtgga tcatatcgct
    68881 gttgagtata tcgcggtatt tcttatacca ttgaataacc tcggttacgg ccgcttgggt
    68941 ttccggggta tcatataggc gtggccctcg atagcaagct tggacaccag ctccgtaatt
    69001 ttgcatcata tgtgttttgt attcgaacaa gtgttcgtgg aggggctcca aggtggcggc
    69061 ctctcctcct ccttgatact ccacgagagg aacgaagctc cagcatgccg aagccatccg
    69121 atcccatgta ccatcataat tcaattggcg ggcatggatg atctgccggt cccggggaag
    69181 cgaccagttg gcttcacggt aaccaatgcc tgtcttggta gacccgttca agaaatagaa
    69241 atcgggaaca ttgatataaa tgccattctc gcacatccaa cgatagagat cggttatctt
    69301 atggaactga ttccattggg aatcttccag ccctttatga taggtatggt gggtggaggc
    69361 gcatacgtcg ccgggatagg agccgtcgtg ctcgaagcaa cgcatgcccg tacgctcgaa
    69421 gaaggttcgt atatgatgga aatactcata tccccaatcg ctgcacaggc agggagcgct
    69481 accgaaacgc atgcctcccc gtttgcccgt cttgggattg ataacatcca cctcgtcgct
    69541 gatccaacgg cttgataaga gggagtaaca tcctaactct acacctttgc cgcgggcgta
    69601 atctaccaag gatttatatt tggcgatatt ttcttccgag atatcctcgg cgttcaatcc
    69661 agacccgaag ctgatgatca ccatctcgta gcccacggta gcgcattgat cgatagcggt
    69721 acgaataaca tccggatcgg aagaggtaag gtgcatgaag atcggattct ccgtagccca
    69781 tggagctacc gtataatgaa agcgtcgttt gaacaagccc ttccgttccc ggtcatcgct
    69841 gtcgaacggc atctcgtata cgctgaagga cttgaactcc tggcccgccg ctagggtata
    69901 atcgggacct agcttgggcg atacgtctaa tatgcaaggc gtgagcaaag gatagttgcg
    69961 ttgggaggta tattccggat cggctaccca tttctccgtg atatcggttt cccgctcggt
    70021 aaactctccg ccacaagcat aatcgctttc tatatgtatg ttcgggagcc tgaatttgga
    70081 gggatctcca ccgccgggag actccggttc ggcgaatgcc agatattcca attgaaaggc
    70141 atcgatatct atggactgcg gggtcttgtt ggtaacctcc atacttttcc ggataaccgg
    70201 gatatgatcg tataagtcgt aatggagttc tacggtgaca ccttctgttt ctttctctcc
    70261 tttcaatacg aaagtcagtc ttttccctgt gggtacgttc ttattcagtg cccagcggct
    70321 tctggcccat ttgatatctt cctgcagctc ctctatgcgg aaatcctcaa tgagaaaaga
    70381 accggagcgg gtagtcatct gctcgaccca ttccatctgg aagtatccgc gctcgggctg
    70441 gccggccagc ccgccaagtt cccaacgttt cccgtcaatc gtcaaactgc cttcgctact
    70501 tacggcacga agcatacttt ctccggtcat ccggttaaag atatctagag tggagagatt
    70561 gggcaagaca cggaacatac gtgctaccat tccgtttgac aataagatgc ttttgccatc
    70621 gggagtcgca tatatgccgg ctttggatcg tgagggttgt aaaagccagt cgaaagaggt
    70681 gttttccaaa ggaagccctt gttggggcaa tcgcttgatt ttatcaagta atttcttctc
    70741 cgtaccggat gatacctccg gccctttccc ttgatagctt gtggagatga tcgaggggat
    70801 gatctccata tactctattt ggggcgtgat ccataaggca tgatctccgc tggggccatc
    70861 gtcggtaggc tctacgataa ggtccaatat ctttatgcca tttaggggga tatcgattgt
    70921 tttcggggcg tcgccaagtt tgacgatacc gctgttataa agctccttgt catctccttt
    70981 caagataaat aagaccgagc ccggatgtac ctttccgtct ttaccttcta gaccaacaaa
    71041 tgtcttggcg ttttttcggg tatcgaaata cattttcgtt ccgtcaacaa aagggataac
    71101 cgtgaggctt ttatctgtat aatcgatatg tgagtcggcg atcccgacct gtgcttgaaa
    71161 gcgtgacgca ttcttgtgta aatcgatctt gatatggctt ttggcttgta ccccgatcac
    71221 gtcatcatac gtttttcctt gtatggaggc gggctcgttg gtaactgatt tccctttgac
    71281 ggcgccaccg taggtttggt aggatttatt taggtccatg tccataagcc ggatctcgtt
    71341 ctggcccatg gcgtagagac cggcaaatcc cgaaaggata gctgtaaaga taagtttatt
    71401 cataaaatcc agtgataaaa gagcgtgtta tcaatgataa aaataaggtg cttcaaaaag
    71461 acttcttttg aaacacctta ttgggtttat aatctagttt cgttctatta taatgtcgta
    71521 agttttaaat tacgccaaag aaccttgatg cctccaccgt cgtgaatctg aagggcgatg
    71581 cggcctttgc cggctccgat cttctcgtca ttcaagttta ccatttcctg tccgttcagc
    71641 caagtctgta cgttgtcgcc ttgtaccttg atacgcatcg tgttccaatc gccctctttc
    71701 aatatattct ctttctcgtc cggaatctga accagccagc cacgtccgta cgactcatag
    71761 ataccacctg tatcgtgacc cttcggagct acttctacct gccagccgtt tactttcacg
    71821 ccttcctcta cgaaagagcg gatgaatacg ccggagtttc cgtcagcctc ttgcttgaac
    71881 tctacggtta gatcgaaatc atcgtaataa tcacgggtag cgagataacc gtattgtttg
    71941 tcgggaccgc tttcgcaaac caataagccg tcttttacgt accatttctc cgtaccgtat
    72001 ggttcccatc ccgtcaaatc cacgccgttg aacaagttca cttctttacc ggtcttacgg
    72061 ggaagttcct tgatcttcaa gttacggaaa gatgcgggat aaccatgatc ttgcaaacaa
    72121 agcacacctt ttttcgccaa tccgtattcc ggtgcgttgg cccatttacc gctatttttc
    72181 ttagcgtgcc aatcgtctgt ccatgcctcg aactcaacga tcttttgtcc gttcaaccaa
    72241 tgttccacat gtccgttatc gaatacgatc ttggagttgt tccattcgcc ttgcggattc
    72301 accttcatct tggatttatc cggcaagtgc atcgcgtaat ctacgcctaa tttctgccac
    72361 tcttccaatg gctccgggaa gttcggctcg tcgatcaatt gatactccgg ccctgttacg
    72421 taaggaacag catattgggg acgctctacc acgtggtaca acataccgct attgcccccc
    72481 ttggacaatt tccagtccca agaaagctcg aagttctcat actctttatc ggttacgatg
    72541 tagccactag cgtcgctgcc atcacctttg gcttggatac aaccatccac tacatgccaa
    72601 ggctgtgtca atgtagtccc gttgtaatct ttccaaccat ccaatgtctt tccatcaaaa
    72661 agcaggaccc atccgtcagc gatttcctcg ggagtaagtg tgttttgttc ttgactggca
    72721 caagaggaaa acaaggccag cgataccgca caagaggcta acaagcttgt ggcggctgtt
    72781 tttttcatta cagattccat gtaaataaag aatttaggtt gataaattgt aactgaatgg
    72841 caaatttacg taaatatctt tgatatctct ctctgttgga ggaaaaacgc ttctctccct
    72901 aggaaatact tctccaagag cctatatatt ctttgtcgga taagctctat ttcttaattt
    72961 ggcggcgctg aatttatatt cacagccgct gaatatacaa atgccgccgc tgattgtaaa
    73021 atcagtggcg ataatttaag aatagaatag gtaccgatca ggtttaccta taggtacgca
    73081 taagttttat tctggcacaa tcaactttta tatgtttttg tggaaaagaa tctggataat
    73141 acttgtttaa tcgaagaata atatagatat tgcatgcatc taataaagac tgaaataccc
    73201 tgcaaaccat atgataacaa taggcacctt aaaactagat ttagttgcgg atcgggaacc
    73261 tttcgttcat gatttatatg gtcgttggga tacctttaac cgaacctctt tagaagggat
    73321 cgtggatgag attttaagcc gttatgatac ggaagatgag
//
LOCUS       DBMDTB010000007        69639 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_173_length_69639_cov_11.092899, whole genome shotgun sequence.
ACCESSION   DBMDTB010000007 DBMDTB010000000
VERSION     DBMDTB010000007.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 69639)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 69639)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..69639
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_173_length_69639_cov_11.092899"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(446..856)
                     /locus_tag="ACZPB4_02180"
     CDS             complement(446..856)
                     /locus_tag="ACZPB4_02180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN domain-containing protein"
                     /protein_id="HIR1097064.1"
                     /translation="MRRYLLDTNICIFYMKGKFHLNEKIDDKMKRYCFISEITIAELL
                     YGATCSNRKDKMLKEVESFISQFTVLPIYGSLLMFAELKSTLRSQGLLIDDFDLLIGA
                     SAVANDLILVTENVKHLERIPHLKIENWIDRAKI"
     gene            complement(853..1095)
                     /locus_tag="ACZPB4_02185"
     CDS             complement(853..1095)
                     /locus_tag="ACZPB4_02185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097065.1"
                     /translation="MDTTVKIADSYINLLSSFSDEIKLRVIRKLSESLLRGKKKETSI
                     QDSFGAWDDDKSAEEIIAEINKARVLGTRSIESFDE"
     gene            complement(1506..2750)
                     /locus_tag="ACZPB4_02190"
     CDS             complement(1506..2750)
                     /locus_tag="ACZPB4_02190"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012056118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HIR1097066.1"
                     /translation="MNKRIYLCLAHMSGKEQMYIKEAFDTNWVVPLGPNVNGFEKDLE
                     EFVGEGKHVVALSAGTAAVHLALLACGVKPEDEVLVQSFTFCASSHPITYLGATPVFV
                     DSEVDTWNMDPVLLEEAIQDRIEKTGKTPKAIVPVALYGMPYKVDEIMAVADRYGIPV
                     IEDAAEGFGSRYDGRMLGTFGKYGVLSFNGNKMITTSGGGALICPDGEAKREIMFYAT
                     QAREAYPYYQHERIGYNYRMSNICAGIGRGQMTVADAHVAHHKHTCDLYRELLKDVRG
                     ITLHENPSGRFDSNYWLNTIVLDPLLRVKGQENAYQAMVQGAVGGAGGVTHAAVNAHT
                     DCEPNANVEAMRVGLDAMGIESRPLWKPMHKQPVYKDCPAYVNGVSESLFKVGLCLPS
                     GPYVTDRDIEYIVGGIRGLIER"
     gene            complement(2764..3444)
                     /locus_tag="ACZPB4_02195"
     CDS             complement(2764..3444)
                     /locus_tag="ACZPB4_02195"
                     /EC_number="3.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019213 - deacetylase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L deacetylase family protein"
                     /protein_id="HIR1097067.1"
                     /translation="MFKNILVVAPHADDEILGCGATIYKMMQEGHNVYVLIMTNASKS
                     DPNIFSEKGIQRVRTEALEAHRLLGVKQTFFFDFPAPALDQYPGYIMSREVSKCISEN
                     QIDTVFIPHRGDIHKDHRMVFDSVLVACRPVGDYTVKRVYTYETLSETEWAAPYADDA
                     FIPTVFIPCSQDGMKMKLRAMECYQSQLRRFPSSRSLEALEALAKYRGATISVERAEA
                     FMLIRSIF"
     gene            complement(3447..4400)
                     /locus_tag="ACZPB4_02200"
     CDS             complement(3447..4400)
                     /locus_tag="ACZPB4_02200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097068.1"
                     /translation="MELDLRDTGELFNGSEVCRLNLNRAGIYHCCRLLNVNKVLLPYY
                     ECFTVRNFLLGKGFKVDYYHIDKDFMPLDISQDDDTAIVFVNYFGLMSTEHMLSLIEG
                     YKNVIIDNAQSLFAKPINGVYNVYSPRKFVGVPDGCYVVGPDAVRFSDEYDQDLSSET
                     AGFLLQRIEVGCNSAYQYRQLNEKRIDMSNISRMSILSRAILKNAPYDYIKNKRFENF
                     NLASDLYSSMNKINPHIYFDDNCVPFVYPLVVEKSDMVDLLSKEKIYTGRWWNYLLKE
                     TDSTSFEYYLSSYMIPIPIDQRYGKNEIEYVYNIINKYLTK"
     gene            complement(4405..5103)
                     /locus_tag="ACZPB4_02205"
     CDS             complement(4405..5103)
                     /locus_tag="ACZPB4_02205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WbqC family protein"
                     /protein_id="HIR1097069.1"
                     /translation="MKVAIHQPDYIPYLGFFYKMYKSDLFIYLDDAQFSNEAAHNFNK
                     IKTPQGVLRVKFPVEMKFGDPINHVRPKDELKWKGKHLKTIEMNYKKAPFFSDIYPSL
                     KEVYLNDYSNVADLNIALNTFISNQFGIKPKIFRSSELLSHAKKEERVIDLSLEVGAT
                     AYISGNGARVYQDESHFNERGLKLEYMDYSPIEYPQLWGDFIENMSVLDYIFNCGFDF
                     EYVVDKVDAINGNR"
     gene            complement(5078..5722)
                     /locus_tag="ACZPB4_02210"
     CDS             complement(5078..5722)
                     /locus_tag="ACZPB4_02210"
                     /EC_number="2.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HIR1097070.1"
                     /translation="MMYRYIKRIIDFILSLFGIVALIPIYLVLIVVIRFKLGSPIFFI
                     QERSTLNGRSFSLLKFRTMTNKTDSDGNLLPDELRKTSFGSWLRNTSLDELPELLNIL
                     KGDMTIIGPRPMPSKYNIYFSDYEKKRFKVRGGLLPPEVLKDNPTPTWDEQLQWEAEY
                     GEDCSFFIDLKILFRTFRLLIHRKNDNYGEYVRKSLSEERTEKNNAYESSNTSA"
     gene            complement(5750..6217)
                     /locus_tag="ACZPB4_02215"
     CDS             complement(5750..6217)
                     /locus_tag="ACZPB4_02215"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HIR1097071.1"
                     /translation="MEKKTFRQRVSKVVRGIYTNYLKYVKKVDIGKGVSISQRIDMDK
                     VNPRGIHIGDETRVSVGVMLLAHDYFRGKNKVDTYIGKRCVIGGRAIITPGVTLGDHV
                     FVGAGSVVTKSFPSHCLIAGNPARIIRTGIEISEKSQIVNFGTLVKNKESEKK"
     gene            complement(6256..7314)
                     /locus_tag="ACZPB4_02220"
     CDS             complement(6256..7314)
                     /locus_tag="ACZPB4_02220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HIR1097072.1"
                     /translation="MARWEIKNVGMKGVAMAVPKNVVTTSELGLLSQEEADVFDNTVG
                     IKRRHIAPDTMCASDMCQAAAEKLLVELGWEKDSIDVLLLESVTGDYRTPPTSCVLQD
                     RLGLSENCFCMDIPMGCCGCMYAITVAGNLLTAGNVKRALLLIGDTALRMGSMKDKSR
                     VPLFGDCGTAIALEYDEVANDIVVDFHTYGKGYEALMTPHGGFRHPATPASFEYEDFG
                     NGIVRAPIHTLINGMNVFSFAISRPPKSVEAFLADYNINRETDIDYFLIHQANKMIVD
                     RIVKKLKLPKEKVPYNLEEFGNLGGASIPSLMVTRIADQLRTKETTLLMSSFGLGLSW
                     GTMWVKTKPMIVSTLVSI"
     gene            complement(7326..7565)
                     /locus_tag="ACZPB4_02225"
     CDS             complement(7326..7565)
                     /locus_tag="ACZPB4_02225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HIR1097073.1"
                     /translation="MTNIEKYNNAFVEVFGVEIAVLDDGFSKDSVDAWDSVHQLNIIA
                     LLEESLDIMFDPEDIMEFTSYGKGREILKKYDVEL"
     gene            complement(7578..8975)
                     /locus_tag="ACZPB4_02230"
     CDS             complement(7578..8975)
                     /locus_tag="ACZPB4_02230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HIR1097074.1"
                     /translation="MILGLNERPQDAVAAIDASGAVLRYGELLSFSERIGSLLPVRSL
                     LFLLTENNVGGIAWGMGSIHSGNVPLILNAHIEEGLYHNLFEIYRPSYVCLPTRMASA
                     LRYEIVCECYGYTLLHTGMEPCTLHADLSHLLPTSGSTGSPKLVRHKYENIEAAALNI
                     STFFGLTSDDRPLLVLPLYYTMGLSVVFSHLYVGSTVLITNQSMTDKAFWNFMKEQRA
                     TSFTGVPYSFEILNLMRFFRMDLPDLTLLTQGGGKMSRQLNLKFAEYCRDNGKRWIAT
                     YGQSEGTARMAYLPAEWAIEKVGSIGRAVPNAELSLIDSEGNRIEGANTEGEMCYRGK
                     NVTMGYARSREDLSLGDERNGFMRTGDLAYRDEDGCYYIVGSMGRFLKLFGMRIGLDE
                     CEQIIKGKYPIECACVGTDEKMTVYLTDERYAMVVKEVLVEKTKLVASAFEIKVIDEI
                     PKNEAGKILYSKLNS"
     gene            complement(8990..9748)
                     /locus_tag="ACZPB4_02235"
     CDS             complement(8990..9748)
                     /locus_tag="ACZPB4_02235"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HIR1097075.1"
                     /translation="MGRFLENKVCIITGAAQGIGKSIAERFVGDGAIVYACDLQEGSM
                     DVWAEQCVAVQGIGVIPLYFDVTDAAAVKSAFMSIFKREGRIDVLVNNAGVVFNKKIG
                     MIVRPETEQMFRVNVIAVIEMVQLVSRLMARNGGGSIVNIASVTAVLGSPGQSAYSAT
                     KGAIMSFTKSAAKELAPLGIRVNAVAPGIVKTERFSELYEESGEKIDTRIQKIALGRL
                     GTPEDVANACAFLASDRASYISGQILGVDGCASI"
     gene            complement(9754..10503)
                     /locus_tag="ACZPB4_02240"
     CDS             complement(9754..10503)
                     /locus_tag="ACZPB4_02240"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HIR1097076.1"
                     /translation="MYNPFSLEGKTILVTGASSGIGRATAIECAKLGATLILTGRNVQ
                     NLHETLQTLEGGKEHRFIVADLSKEDECGELIASLPMLDGFVCNAGIGKMIPVQFYSS
                     EVLEEVFGVNVFAPMLLMKLLVRKRKMKNPSSVVFTASISAYGNVAPANGIYGASKSA
                     LSTYMKYAALELAGKGIRCNAVHPGRIQTPLIENKLLTMEDVAKDIDVYPLKRYGKPE
                     EVAHAIIYLLSDASLWVTGTHLVIDGGRSLK"
     gene            complement(10503..10733)
                     /locus_tag="ACZPB4_02245"
     CDS             complement(10503..10733)
                     /locus_tag="ACZPB4_02245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000035 - acyl binding [Evidence IEA];
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HIR1097077.1"
                     /translation="MEMTDFIEKLAEQFDDVDAGLLTTETKFHELDDYTSLVALMIIS
                     MIDEEYNVTVTGDDMKKQVTIGDLYNLVSSRL"
     gene            complement(10753..11382)
                     /locus_tag="ACZPB4_02250"
     CDS             complement(10753..11382)
                     /locus_tag="ACZPB4_02250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HIR1097078.1"
                     /translation="MKNLIIIAAGGMGRTLYDMSRESRGYGEEFVVKGFIDDNLYALD
                     GFTNYPPILDRISTYIPQKDDVFVCSIGGAIRKKCMEELINKGALFISLIHRTARIGT
                     NVKLGVGNIVGAYTSIGADAKIGSYNLIQSYTVIGHDVQMGDWNRVDTHVTCVGGTVI
                     GNEADIYTSSVLNHGVVVEDRAHVGACSFVIRRVKEGTTVMGNPAKKLM"
     gene            complement(11431..12411)
                     /locus_tag="ACZPB4_02255"
     CDS             complement(11431..12411)
                     /locus_tag="ACZPB4_02255"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HIR1097079.1"
                     /translation="MKKISIVIPCYNSENYISICIDGLKKQLFDDVEFIFVNDGSTDH
                     TLNYIKKFEREDDRVVVIDKPNEGVSKARNDALDVARGEYVYFLDPDDFIDASWCEEM
                     YVLASKYHADILIFNFYNIVNGIKHFCLTNIPVGVYNLENILMFVDYLPITPKLYRRE
                     IIKNVRFNTNIKVGEVFDFFIGVLLNTHRIYVTDRFYYNYVRHIDSATKNLNMNVDLS
                     IVDTLYSIDERVRKSECKIVTSKCFVYSVCKLLNGFVFNKYVKVVALGKARDLVDYVY
                     TDSLVRKYIKERVRMTSWSSPAKYYFMLLYVSPKLLYFILRSCLRLKFIK"
     gene            complement(12408..13466)
                     /locus_tag="ACZPB4_02260"
     CDS             complement(12408..13466)
                     /locus_tag="ACZPB4_02260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpsG family protein"
                     /protein_id="HIR1097080.1"
                     /translation="MFCCASIASYREHVTIHKNLFFRWEIILMLLSFAVVFGMRYDVG
                     EDHLGYLDGYINPFLHKEYEPLFALIRDTLSNAGVHPIVFFAVCAFIQVFCLFYFMKD
                     CKFLYPALIVSLFMGQFFIHWMNGIRQDIAGCIFLCAITCVIDKRIVGFFTLVLISVG
                     FHYSAVILFPFYFLYLKKDHYFNSINVQYLLLFVVSYVAIYNVDLLTNINDTIFYLAT
                     LSGYEMYTEDVLYRFADITKTGVSMYVFILLDLIIVSYCKKMKCYYYGRKFNIIYDLY
                     FFGTLAQIVFVNNLVLARPFRYFRGFKLVVIACLIFFLYKKSRQSINAAVLFMVVVLL
                     LILFAATIKNEPFHFMPV"
     gene            complement(13571..14575)
                     /locus_tag="ACZPB4_02265"
     CDS             complement(13571..14575)
                     /locus_tag="ACZPB4_02265"
                     /EC_number="2.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide pyruvyl transferase family
                     protein"
                     /protein_id="HIR1097081.1"
                     /translation="MKIGILTQPLRGNYGGVLQNWALQHILIRLGHEPITIDILPRPS
                     IGRFILSTIKSLLLWFIPSRRRRFKRWRERRMPLFEEFVSKNIIKTPTCRNYSMEMIR
                     EYGLEALLVGSDQTWRPIYNVNRLSDMFLHFAGNFSGKRVAYAASFGVDYWEYSEKQT
                     SVCSSLAQLFDAVSVRETSGVALCERYLGIDAVAVLDPTLLVRKETYAELCMKVPVFK
                     KRYLAAYVLDSAKEVDLIITEEAKKRGLPILRYSAYGQAKLTIEEWIAIFRDASFVIT
                     DSFHGTVFSIIFEKPFRCVVNERRGGVRFADLLEKYHSGKLVEWREKSLDFLREALNG
                     "
     gene            complement(14983..15306)
                     /locus_tag="ACZPB4_02270"
     CDS             complement(14983..15306)
                     /locus_tag="ACZPB4_02270"
                     /inference="COORDINATES: protein motif:HMM:NF013884.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HIR1097082.1"
                     /translation="MVRDYSIDSVKGVCLLHMFVLHIFIIYGFFDAKGAASEFYFNAL
                     SFFMSSFYFFSGFFFKSPENGNEMKYIRSKVKKFIIPLITWSVISLPFVYCKDYSLID
                     INTEG"
     gene            complement(15410..16243)
                     /locus_tag="ACZPB4_02275"
     CDS             complement(15410..16243)
                     /locus_tag="ACZPB4_02275"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HIR1097083.1"
                     /translation="MGIKSYIVNFLKSLKHGGVKYVSVTFTNPDARYANKKVFISGGS
                     EGLGRAMAKAYLAEGAEVIVTGRSKEKLSNFQLSESNAKLYTLVWDALDFDSYKQKFD
                     EAVSMMGRIDIFVNNVGGGMSKYEPWNAYTAEVLDRTYDINTKSMFLMCQMEGLYMID
                     NKIKGNILNITSIAGYQRLFDPYAVAKWGAHSLTGGIARKLIAYDIVVNGIAPGTCLT
                     SNPALPHNRNFEDNAYFQGQPSKRFTMPEEIAKTALFLTSGEARQIVGYIIPVDGGVL
                     I"
     gene            complement(16246..17151)
                     /locus_tag="ACZPB4_02280"
     CDS             complement(16246..17151)
                     /locus_tag="ACZPB4_02280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097084.1"
                     /translation="MKHYIKNKINTFIKSSHWYNEVLFKDCVKFWEMKEEPLDVVNLG
                     SSSGVYDFDYSDMRCKGMNWAVAPQTMVGDFLILKRYRKFLKDNAIVFYPLCPFTSIS
                     GAVDYIEDRCYSFLDYRTIPGGHYIRNSKIKGYKNSPISIYPLVEFIRDIRTRVFSSK
                     DVIMRDRQLERDAENWIKGWTVQFNINNLNDKFVESHRTVYDRTISMLKDMIEYCKEE
                     KLRLVLVIPPMHRSLCRKFPAAAKEQLIDSFITEANGGETWYFDCMEEPGFSDDKSLF
                     RNCYYLNKRGALLFTKYIMEKIDNK"
     gene            complement(17181..18722)
                     /locus_tag="ACZPB4_02285"
     CDS             complement(17181..18722)
                     /locus_tag="ACZPB4_02285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HIR1097085.1"
                     /translation="MSQEVSSTNKRIAKNTLFLYVRMLLVMGVSIFTSRVILQTLGVE
                     DYGIYNAVGGIVAVIGVLNGALSSSTSRFLAYELGMKDAEMLKRTFSVSLNLHMAVAF
                     IVLLLAETIGLWFFYEKMVIPVERLSAAWWVYQFSIVTVMVNFTQVPYNASLIAHENM
                     SIYAYVGLYDAFSRLAIAYLLSLSPMDDLVFYALLLMLNTFLIQFFYRFYTYRRYQEC
                     RFRWITDKTLYKRQLAYSGWEMFGGLASISQGQGINILLNLFFGPMVNAARAVAYQIQ
                     TAVNHFVINFLMATRPQVIKSFAEHNYERMYSLTFKSARYSFFLMLALILPICFELRF
                     ILNLWLGKATPPDTYVFTLIILLLSLAEVFRASMIMAFHAIGKMKLGNSLNGTIMILS
                     LPISYAILKMGAPAYAVFIVLVIINITVMIDAYFIVYSYVHFNIRELLVGAVLPCVLV
                     GACSVIVPTAIVYLMEDGWQRFIILSLLTEVVLMILILYVGITRAERKKIVSWIQTKM
                     SKTKQ"
     gene            complement(18764..18997)
                     /locus_tag="ACZPB4_02290"
     CDS             complement(18764..18997)
                     /locus_tag="ACZPB4_02290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HIR1097086.1"
                     /translation="MREKIISILSELRPEFDFSEPVNFIEEGMLDSFDIVTLVDTLDT
                     EYDIVIDGIDIIPENFDSLDSIVRLLQKNGVNE"
     gene            complement(19035..19841)
                     /locus_tag="ACZPB4_02295"
     CDS             complement(19035..19841)
                     /locus_tag="ACZPB4_02295"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIR1097087.1"
                     /translation="MDKIDSLDKINGFVSDIRSLRKGYLSNFFLDRKKHSIWIEKGEL
                     FYVSFPDGYFLLHLTDSVNNLFFLTTTLQQLVGGLKAVLPILSEQLVVDIVGDGKIAS
                     LKDVFVEQGFSVYEQLYRMSRLGALEYKVSDVPNVCLAEEADACVVQDMLHTNFDPLS
                     EQLPCYEEILDFISRKGVLVYKEKGKVYGFIIFELNGQTLYLRYWFVLPEYRDLKIGS
                     RLFNEFMRAGHATKRQLFWVIASNENAIKRYRHYGFEVERLYDYVLIRNK"
     gene            complement(19834..21393)
                     /locus_tag="ACZPB4_02300"
     CDS             complement(19834..21393)
                     /locus_tag="ACZPB4_02300"
                     /EC_number="6.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009016945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043038 - amino acid activation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid adenylation domain-containing
                     protein"
                     /protein_id="HIR1097088.1"
                     /translation="MTDPLLVRIEKYLLDMQKSVIEYLQSTVSRFPAKIAVKDSEMSI
                     TFGDLWRNAQKISAALVNTNIGLNNPIGVYIPKGGKMIESFAGINMSGNFYVPLDTKS
                     PVSRVSSIIKTLESKVLITDRSHIETLRDFTHVRILVAEDIIEGDINIENAFSQFTHQ
                     IDTDPVYSIFTSGSTGIPKGVVVSHRGVIDYIDWAKDTFHFMSDAVIGNQAPFYFDNS
                     TLDIYLMYSTGATLNIIPESNFAFPAKLVDYLNEEKITFVFWVPFVLINVANLNIFET
                     KKPIYMKDVFFAGEVMPNKHLNYWRKHLPNCRYANLYGPTEITVDCTFYEVKREFSDS
                     EPLPIGFPCRNSDVLILVDRKRRAAKGEQGELCVRGSSLALGYYNSPQKTASAFIQNP
                     LHNYYPETIYCTGDVVYENEYGEIMYVGRVDSQIKHNGYRIELGEIETAILGSHMVDS
                     CCVVYDFANKKIVMFYQATEELDMATFRKVISTSIPRYMQPTVYHHIRELQRNTNGKI
                     DRLFYNNQVNG"
     gene            complement(21390..22367)
                     /locus_tag="ACZPB4_02305"
     CDS             complement(21390..22367)
                     /locus_tag="ACZPB4_02305"
                     /EC_number="2.3.1.-"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP synthase III family protein"
                     /protein_id="HIR1097089.1"
                     /translation="MKTIIPDVSIRSIASWLPSNKISLSSFAEQYGEKETRDVIRTTG
                     VEWVYRTDANQKSSDLCFNAAEYLISKDNIDRESIDGLVVLTVTRDWALPDTSVYLQH
                     KLGLKNETVCLDINYGCTGYIYGLMQAAMWIHSGLCQNVLVLGGDMLKNCLDPKAVGS
                     IDASDIGTASLISKGTTGMAFHLCSDGARYDRIMMPHGGYIYQDGMGVFSFSIVNGPK
                     SIRTVMDLMKWEDSDVDIYALHQSSQLIIKNVRMALKSSQEKFPVNMKDFGNSSSSTI
                     PNLLCDLYGLNKANRPRHAVFCSYGAGLTCGSVALDLSKTHFYEPLNKQ"
     gene            complement(22364..22597)
                     /locus_tag="ACZPB4_02310"
     CDS             complement(22364..22597)
                     /locus_tag="ACZPB4_02310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000035 - acyl binding [Evidence IEA];
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HIR1097090.1"
                     /translation="MELKDFIGKFVSQFEEEDPAIFEADLDFHELDSWSSLTSLSVVA
                     MVYQEYGVELDTQDVRNADTIEDLFNIVKERKA"
     gene            complement(22616..24433)
                     /locus_tag="ACZPB4_02315"
     CDS             complement(22616..24433)
                     /locus_tag="ACZPB4_02315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Coenzyme F420 hydrogenase/dehydrogenase, beta
                     subunit C-terminal domain"
                     /protein_id="HIR1097091.1"
                     /translation="MIQITDKSKCCGCNACGDVCTHKAITFKTDIEGFWYPEVDKNKC
                     TDCGLCEKVCPNLHSEELKKNDFEIPVCYAAIHKNIEVRFDSTSGGAFTALAEYVYKQ
                     GGYVGGAVYNEDWSVSQFLSADKTDLPRLRSSKYLQSRFDGFYIAVREALKTGKPVLV
                     CGGPCQMAALRGFLHKTYDNLILVDYICRGIASPLLFRKYIEYLENKHHSKVVYFKAK
                     NKELGWRKHTFKILFENRDVEYQTLENNPWRILNYIVPEVCRPSCFECPFKGFPRATD
                     ITIGDLWADKKYIPKELDNDLGTSVVFVHSKKGADLIQNIKTLKKQDFPLDKAIAGNR
                     LLMKPLCHSSHDRDAFYATLNESLDACIKKYLPHFGKKGFSVKEKLKNVARFLFSVKK
                     ASGWSLGTWTKNFRYNFFCGQVKGNVLEGKFFIINKYCTIVMGSKAQLILNAPFYFGS
                     KRVKGSRLDSRLLIENGGRMEIKYEPYSVAYGADIEVFRNATLEIGGGLGANIGLTII
                     CADHISIGRYTGCGRNVTIRDNNGEHFISIRGYKTSSPVTIKEHVWLTESCTVMPGAV
                     IEPGAIISARSVVSGHIPAFSIVKGDPAVVVEKNILWKA"
     gene            complement(24574..24807)
                     /locus_tag="ACZPB4_02320"
     CDS             complement(24574..24807)
                     /locus_tag="ACZPB4_02320"
                     /inference="COORDINATES: protein motif:HMM:NF024861.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide-binding protein"
                     /protein_id="HIR1097092.1"
                     /translation="MTKLTLDVILNNLYISFLTPYYKFNLIKSDPNDNKFLNYAVIAN
                     AKFIMTEDRHFVADTVWKNKQSQLKAINTILSL"
     gene            complement(24967..25191)
                     /locus_tag="ACZPB4_02325"
     CDS             complement(24967..25191)
                     /locus_tag="ACZPB4_02325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097093.1"
                     /translation="MEVTVFNPVQQHLLKFFAFDGSEEKLLEMKAVLTKYFSQKLDKR
                     LDELWDSRGLNQEKLDELRTIHFRIDLNDE"
     gene            complement(25300..27234)
                     /locus_tag="ACZPB4_02330"
     CDS             complement(25300..27234)
                     /locus_tag="ACZPB4_02330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HIR1097094.1"
                     /translation="MMDFHKGRWRLALGRLVNLRYINRWIIFSADLFVSLSVSLLGVL
                     GMFSILHIRIGEPDVLKVGLSSFVASIVSFLLFKAYHGVIRHSTLRGLWRIGGAAIGK
                     SLLMFLLLWLLKARFSPSIYWLGGIMDSTLTIVMLVTLRVFVINVYNSVLLQLGKKRK
                     RVLVFGTEEESVMIATSANRQVFMQNYSIMGFLSFGNSKKSIRIAELPVYQIENVEDL
                     YRLIPRNSLDGVLFPNIKVAHQERDRLIRYCEQASLKTLVVPEMEELRGGEAKRSVRE
                     IRIEDLLGREEIHINLDEIGNLLEGKTVLVTGAAGSIGSEICRQLAHFPIKKLVCFDS
                     AETPMHNLRLELEEKYKGLNFVPVIGDVRSPDRVDYVFRNWHPQVVFHAAAYKHVPLM
                     EENPCEAIRTNVFGTRVMADAAVSYGVEKFVMISTDKAVNPTNIMGCSKRLAEIYVQS
                     LSLAIERGEVKGETRFITTRFGNVLGSNGSVIPRFREQIAQGGPVTVTHPDIIRYFMT
                     IPEACRLVLEAGTMGKGGEIFIFDMGEPVKIADLAKRMIELSGLQVDKDIEIKYTGLR
                     PGEKLYEELLNNKENTKETPHEKIRVAAVREYDYKDVITHIHVLIELSLRVQILPMVR
                     EMKVFVPEFKSQNSRFEELD"
     gene            complement(27231..27467)
                     /locus_tag="ACZPB4_02335"
     CDS             complement(27231..27467)
                     /locus_tag="ACZPB4_02335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097095.1"
                     /translation="MTENYERAEQARFVFHIYGCNVQIVPNATHAIQIIHHGDGTILR
                     TESCITPAASGRHESQAPPLGKVRALNIKQTKYK"
     gene            complement(27599..28030)
                     /locus_tag="ACZPB4_02340"
     CDS             complement(27599..28030)
                     /locus_tag="ACZPB4_02340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097096.1"
                     /translation="MSDITITIHGGNNQILPNATEAIQNFYVGEYCGETSQEEGDGRS
                     GLMPETIRFRAYINKEEDLERYLAQIVECRTVTELPQVILVMQENEPKITPEEMVKER
                     FIRLFLPITPRITKGKSVSNICARINDAWSSRLRHRSTGRF"
     gene            28164..28652
                     /locus_tag="ACZPB4_02345"
     CDS             28164..28652
                     /locus_tag="ACZPB4_02345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HIR1097097.1"
                     /translation="MINYSTYMWKSPLDETAKEQAYAKNQVTKVMSFDDFVKHISDHN
                     GVFTRGTVKGVVSDTCSCLVEQLLNGYKVQFGELGIFSISITCEPAATLKDFSSDNIK
                     AVNILFNPGIDFENLRSKAEFNLVTSRAIQAASLKAVKENKDTVDLAALKKGDSESPD
                     EI"
     gene            28684..28827
                     /locus_tag="ACZPB4_02350"
     CDS             28684..28827
                     /locus_tag="ACZPB4_02350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010182156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097098.1"
                     /translation="MKLILFIYLKTTSMKKTNWKSVLLYIIRIVELVITGAAGGATSG
                     WIG"
     gene            28824..29234
                     /locus_tag="ACZPB4_02355"
     CDS             28824..29234
                     /locus_tag="ACZPB4_02355"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_process: GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HIR1097099.1"
                     /translation="MRTITLIIVHCSANRQGSTLRMMDIDRLHRSLGWNGCGYHFVIP
                     TDGTIETGRPLEQVGAHCKNHNRYSIGVCYIGGLANDGKTPMDTRTEAQREALQGLFR
                     ELHQRFPKALIVGHQDLDPSKSCPCFNVVNEFSD"
     gene            complement(29231..29620)
                     /locus_tag="ACZPB4_02360"
     CDS             complement(29231..29620)
                     /locus_tag="ACZPB4_02360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097100.1"
                     /translation="MRKESETPSGIRLMLLLKGHLREIMNRECANQTSIHLYCTGSYW
                     VAFERSAYQLRRAFPDSEITPMRLYAYPFPVVMVSVTDRSLRLYERKHIAKQNGADYK
                     LLTVPELSAPAYQAWHTREVKGLPALN"
     gene            complement(29634..30731)
                     /locus_tag="ACZPB4_02365"
     CDS             complement(29634..30731)
                     /locus_tag="ACZPB4_02365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HIR1097101.1"
                     /translation="MNIVTSNSSDRAMVHIRNRRSQEAVRWYVLTLPTAVGGRDNIYS
                     SKGLDAELSRRKRCGEPLFEYFAPSYVEARKVGGKMVNTRKPLLYNYVFIHASENEIF
                     RLKRIMPLYNLLPRVSVGEHSYFPYLSDHEMETLRWMAESYSNELPVYVPDSGRLLKG
                     DRVRITSGSFMGMEAEVVVQPGGGHKDVMVRILDCMWVPLFEVRQGEYELIELNTKGK
                     HVYTHLDNDRLSEGMHKALGRYYLSGKLGKEDELLVREVLKGYASLRVETDVMRCKVY
                     SLLLPAYKLLDQEEEFERLYSTLRNMLPLVKAVNSRALLLVTLYGCTNSNLYYRMAHE
                     LVDPWRDDPSPKRSKALLIQRLHDYDIWLKH"
     gene            complement(31235..32166)
                     /locus_tag="ACZPB4_02370"
                     /pseudo
     CDS             complement(31235..32166)
                     /locus_tag="ACZPB4_02370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772726.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0009009 - site-specific recombinase
                     activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            complement(32264..35263)
                     /gene="secDF"
                     /locus_tag="ACZPB4_02375"
     CDS             complement(32264..35263)
                     /gene="secDF"
                     /locus_tag="ACZPB4_02375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein translocase subunit SecDF"
                     /protein_id="HIR1097102.1"
                     /translation="MQNKGFVKVFAVLLTLVCLFYLSFSFVTQHYNSKAAEYAGGDPA
                     KESAYLDSLSTQKVWLGYTLKQCREMEISLGLDLKGGMNVVLELNVADVIRSLSNNNQ
                     DENFNKALDLAYAHQATSQKDFIDLFAEEYKKLDSGARLSAIFSTFELKDKITPQSSD
                     AQVVSVLKQELQSAIDNSFNVLRTRIDRFGVVSPNIQRLETAGRILVELPGVKEPERV
                     RKLLQGSANLEFWETYKLPEIYQQLVAADNVLATILSKEASADSVATDNVEKIADAAD
                     ANVSEADSLLAELGQDKKDTEANQSMEEFAKQHPLFALLQISQYNGQLSPGSTVGIAQ
                     AKDMEKISEYLNMKQVKEVLPRNLALKWGVKAIDDKEQFFELYALKVTNRDGSPALGG
                     DVVTDANADFMQQAGRSEQMVNMVMNAEGSKAWARLTKENIGRQIAIVLDEMVYSAPN
                     VNDEITGGRSQITGHFTPEEAKDLANVLKSGKMAASVHIVQEDVVGPSLGQEAINAGV
                     ISFVLALVLLMIYMCAFYGLVPGLIADGALVLNIFFTMGILASFQAVLTLPGIAGMVL
                     TLGMAVDANVLIYERTKEELRAGKSLGKAIADGYSNAFSAIFDSNLTSIITGIVLFYF
                     GTGPIRGFATTMIIGLFASFLTAVFLTRIVYEALLAKDKLKNVTFTTSLTKDLLTNPK
                     INFLGARKVGYLIPAAIIVLGAISMMTIGLNNGIDFTGGRNYVIRFNQEVKTDDVRNM
                     LDAQLDGSVSVIQIGTADQVRVSTNYKINDNDPTVDQEIENKLFEGVKSLLPEGTTLD
                     EFTTTFIQSSQKVGPSMADDIKNSAILAVIFAMICMAAYILLRFRDVSFSVGAFASVA
                     TTTLCIISFYTLLWKVLPFSMEVDQTFIAAILTIIGYSINDTVVVFDRIRETIALYPK
                     RDRYQVINDALNSTLCRTFNTSLTTLVVVLCIFILGGSTIRSFTFAILLGIIIGTYST
                     LFVATPIAYELQKKKINKKAAAEKAGK"
     gene            35436..36410
                     /locus_tag="ACZPB4_02380"
     CDS             35436..36410
                     /locus_tag="ACZPB4_02380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4468 domain-containing protein"
                     /protein_id="HIR1097103.1"
                     /translation="MKQLLFALLFIPALLFAQEDQHYLAGAVPVADGKVVFTREINAP
                     SLSKAQIYQQLLKWGQENFNTKESRVAYQNEAKGEIAIIGEEYIVFSSTALSLDRAMM
                     KYRIIIECKEHACTLQLAGIRYEYNVSYQNEPEKYLAEEWITDEYALNKSKTKLNRIS
                     GKFRKATIDFADKTFDSAANTLGAQLLTTAPVEPVSAPQRETRPVAPMEGFVAFQADK
                     VPSTILQMLPDNALQIKAVKGNTTDANVEWKGIGNMFGKTISTISISKDSPAYKAIGN
                     NDVYRLSFSKPGTSADAPWIIIECRKQGETSEGQQTMLIGEITNVWIK"
     gene            36431..36985
                     /locus_tag="ACZPB4_02385"
     CDS             36431..36985
                     /locus_tag="ACZPB4_02385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4468 domain-containing protein"
                     /protein_id="HIR1097104.1"
                     /translation="MKKILLLIYMMFPVLVMAQGHKGDVDECAPMKNGKVCYSDDVEI
                     ENTSKLEIFNAINAWAKKSYGKDVFLSNVNSNKNKGTIFVSSKVELLLNDTDKTIIKY
                     KMRITCFDNRYTIEASDIVYQYDPLNDKKYKTYKAEDVIANNGDSNTIALIKDPKLFC
                     NATFFFVENLFADVFDAAQNAESE"
     gene            complement(36996..38093)
                     /locus_tag="ACZPB4_02390"
     CDS             complement(36996..38093)
                     /locus_tag="ACZPB4_02390"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HIR1097105.1"
                     /translation="MKTLRIFLQFLFVVANVVAVVLLIVSAYSDRVSPETSMTLSYLG
                     LAFPVLCVVNLCFIIYWLFLWEWKFLLIGIFSFLLCWGPVKRYFPFHSHKDVPREEVL
                     KVLTYNVMAFGYKNHTKIAPNKIIQYIANSDADIVCLQEYATAKSEKSLTASKIYDAL
                     SMYPYRSVFYQSSTKFQSFGIAVFSKYPLSNSRMVKYDSDYNGSSVHEVNIKGKKLTL
                     INNHLESFKLTMEDRTRYSSLIKSFSSDGLDDLKGAFEQKLGPAFRIRAKQAEAVSEE
                     IKNAKGDYVLVCGDFNDTPISYAHRTIQGDLTDAFAESGRGMGITYNQNFFWFRIDNI
                     LHSPNMTSMNCSVDKVAYSDHYPLWCYLKLE"
     gene            complement(38103..38981)
                     /locus_tag="ACZPB4_02395"
     CDS             complement(38103..38981)
                     /locus_tag="ACZPB4_02395"
                     /EC_number="3.4.21.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012056087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HIR1097106.1"
                     /translation="MDGIFTNLKRMFQSGNILSKLIYINVGLFILIRLASVLFMLFNV
                     QGVPFLQYLQLPASPELLLFRPWTLFTYMFTHFDFLHILFNMLWLYWFGGLFLNFFSE
                     RQLGGLYILGGLAGAVLFVLAYNIFPYFQNVASFSYLMGASASVMAIVFAVSFYRKDL
                     EINLFLIGRIKLIYLAIFTLVIDLLAMTSDNAGGHIAHIGGALFGMWFASRIRNGKDL
                     TAPMNRLIDWFVNLGKRKPKMRVTYKRNETDYEYNARKHQESVDLDTILDKLKRSGYE
                     SLSAEEKKRLFDASKK"
     gene            complement(38962..39684)
                     /locus_tag="ACZPB4_02400"
     CDS             complement(38962..39684)
                     /locus_tag="ACZPB4_02400"
                     /EC_number="3.4.21.-"
                     /EC_number="3.4.21.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HIR1097107.1"
                     /translation="MMNQTNSGFLNSIPPVTKNLIIINLLFWVASLALPKVGIDLVDL
                     LGLHFPGATDFKAYQIVSYMFMHDTHSFAHVFFNMFAVYMFGRVLENVWGPKRFLIFY
                     FVTGIGAGLVQEVVWFFNLRDVIFASQDMINLNGAQIISKSEFLNYFVTIGASGAVFG
                     ILLAFAMIFPNVPLYLMFIPIPIKAKYFVIFYGLAELFMGVASFGGDTVAHFAHLGGM
                     LFGYFLIRYWKKKDADNGRYFY"
     gene            39871..40143
                     /locus_tag="ACZPB4_02405"
     CDS             39871..40143
                     /locus_tag="ACZPB4_02405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030527 - structural constituent of
                     chromatin [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HIR1097108.1"
                     /translation="MNKSEFISAVAEKSGLSKVDAKKAVEAFVDTVSNELKEGGKVAL
                     LGFGSFSVSEKAARKGVNPKTKETIEIAARKAVKFKAGAELNELIK"
     gene            40247..42040
                     /gene="argS"
                     /locus_tag="ACZPB4_02410"
     CDS             40247..42040
                     /gene="argS"
                     /locus_tag="ACZPB4_02410"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HIR1097109.1"
                     /translation="MVIEQQITGAIIAGIKELYGADVTASQVQLQKTKKEFKGHLTLV
                     VFPFLRMSKKSPEQTAQEIGEYLLRNEPAVAEFNVIKGFLNLTVACSCWIDLLNSINE
                     QPAYGIIPVTEQSPLVMIEYSSPNTNKPLHLGHVRNNLLGYSLSKIMKANGNQIVKTN
                     IVNDRGIHICKSMLAWQKWGNGATPESTGKKGDHLIGDFYVLFSNKLKEETHALEAKG
                     LTKEEAEAQSTLMAEAREMLRKWEAGDKEVRALWEMMNNWVYAGFNETYKMMGVDFDK
                     IYYESQTYLEGKGKVMEGLEKGIFYRREDGSVWADLTKDGLDEKLLLRADGTSVYMTQ
                     DIGTAKLRFDDYPINKMIYVVGNEQNYHFQVLSILLDKLGFEFGKGLVHFSYGMVELP
                     EGKMKSREGTVVDADDLMAEMISTAREISQELGKLNEMTPEEAENIARIVGLGSLKYF
                     ILKVDPRKNMTFNPKESIDFNGNTGPFIQYTYARIRSVLRKAAEQGITLPEQLPLTFA
                     ISEKEENLIQMIADYAEIVKEAGKLYSPACVANYIYDLVKEYNQFYHDFPILREENPE
                     LKNFRLVLSANVAKIVKSGMDLLGIEVPERM"
     gene            42050..42928
                     /locus_tag="ACZPB4_02415"
     CDS             42050..42928
                     /locus_tag="ACZPB4_02415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006873 - intracellular monoatomic ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="VIT1/CCC1 transporter family protein"
                     /protein_id="HIR1097110.1"
                     /translation="MNINEKTRKALLRFQQNEITESLLYAQLAAIEKDPSNKEVLLQI
                     ANDEKGHYTILKKYTGQEISPNKLRITKYYWLARILGITFAIKLMEGSEESAKNDYAS
                     YDEYPDLQQIARDEDEHEQRLIALINEERLEYMGSVVLGLNDALVEFTGALAGFTLAL
                     SDSRLIALTGSITGIAAALSMASSEYLSTKSENGNENGKHPVKASIYTGIAYIFTVVA
                     LVAPFIFISNVLMALGLMLIIALSIIALFNYYYSIARSESFRKRFTEMAVLSFSVAAL
                     SFLIGYALKEFTGIDV"
     gene            complement(43006..45354)
                     /gene="topA"
                     /locus_tag="ACZPB4_02420"
     CDS             complement(43006..45354)
                     /gene="topA"
                     /locus_tag="ACZPB4_02420"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009016940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HIR1097111.1"
                     /translation="MQKNLVIVESPAKAKTIEKFLGKDYKVMSSYGHIRDLKTKDFSI
                     DLEHNYAPEYVIPSDKKKLVTELKNEAKKAEQVWLASDEDREGEAISWHLYEVLGLKP
                     ENTKRIVFHEITKNAILHAIETPRDINIDLVNAQQARRILDRIVGFELSPILWRKVKP
                     ALSAGRVQSVAVRLIVEREREINEFVSEAAYRVIASFILPDGTTILKAELNRRLKDKE
                     EVEAFLESCKDASFTIDDISKKPVRKTPAPPFTTSTLQQEAARKLGYSVSQTMMIAQR
                     LYESGLITYMRTDSVNLSDLALGTAKEAILDTYGEKYYKFRQYHTKSKGAQEAHEAIR
                     PTYISNDEISGTAQEKRLYELIRKRTIACQMADAELERTTISVGIGGKKEKFVATGEV
                     ITFDGFLQVYRESFDDENEKEQENGLLPPVTLNEVLSMKDIVATERFTQRPPRYTEAS
                     LVRRLEELGIGRPSTYAPTIQTIQNREYVVKGDKEGTERTYNIITLAQHTIKEVQKTE
                     IVGVDRNKLMPTDIGTVVNDFLMEYFPGVMDYNFTASVEKEFDAVAEGEMVWTDAIDK
                     FYKLFHPIVEEAASVRTEHKVGERELGIDPKSGKPVFVKIGRYGPVVQIGQAHPEDKE
                     APKPQFATLMKGQSIETITLEEALKLFDLPRTIGEYEGKVMVAAVGRFGPFIRHDGKF
                     VSIPKGLNPLSITAEEAIELIEAKKQKDEQRFIKKFDEDPEMEILNGRFGPYISYKKK
                     NYRIPKTIEKPENLTLEECQKIIAEAGEKPAATKKRTTRKKA"
     gene            45516..45779
                     /locus_tag="ACZPB4_02425"
     CDS             45516..45779
                     /locus_tag="ACZPB4_02425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HIR1097112.1"
                     /translation="MEEIKRLISENKLEEAIRLLDAYLTEQPRSDEAWFLLGKAHYKL
                     GNVRLALNSYLQAIEINQESPAQAAYDMAIKVLDFYNKDMYNH"
     gene            46054..46842
                     /locus_tag="ACZPB4_02430"
     CDS             46054..46842
                     /locus_tag="ACZPB4_02430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6261 family protein"
                     /protein_id="HIR1097113.1"
                     /translation="MGTYTKIKPAGLTKLNNAEYTNFMNAFYRLAFAAGGGGGDSESP
                     DEISLDNNPLGITDAQKAAFEKELPLMTDLVNQSHISDETAQLLDLDKQRDDLVVYLT
                     TSVSQMRKSPIEAQRTAAQTVYNIIKPYIGIYKSANQQETAQIQGLLLDLDKEGVPAL
                     IQTLGLKEILDSLRAANDEYAKLTAQRTGNRAASIKEASAVVRLRMDDLYDDMTTIAF
                     VQSVAAPTAETARFVNELNALIDETTALYNQRVGAAKAAAKRKE"
     gene            46893..47306
                     /locus_tag="ACZPB4_02435"
     CDS             46893..47306
                     /locus_tag="ACZPB4_02435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097114.1"
                     /translation="MKKTLLTFTLLAGLSSCTNLSEDLDMIGTQNITQTKSGNLSISE
                     NEPAIVKDLRNYISQIKLQGKQARVLTSYTLTPYIYKEDTIMYIANYEDGWETHQLGI
                     NWGYDGSYDYLWLEASSYSDWVSNTTYDTERYMLK"
     gene            47318..47962
                     /locus_tag="ACZPB4_02440"
     CDS             47318..47962
                     /locus_tag="ACZPB4_02440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097115.1"
                     /translation="MNTSLFKYLMLSMFSLVFFCTCDKDDELSGEEFRVTMENRFFSI
                     KTSKTFTKKDGSTEIMQEGKSYLADSPSTIWFHDSKLYIPIQISSKDTLWQKWNAYQR
                     EKGLGNILLLVGHKYMYESQGNGLITPDQLLVHEQLGGRFYLKTDGDNLLHATILYPD
                     DIADDDTIFPKSEFYYQEELSPDKNVSLEYHVYDSDEEAIAYIIEQMKDWKPSE"
     gene            complement(48112..49284)
                     /locus_tag="ACZPB4_02445"
     CDS             complement(48112..49284)
                     /locus_tag="ACZPB4_02445"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PP2C family protein-serine/threonine
                     phosphatase"
                     /protein_id="HIR1097116.1"
                     /translation="MAIKILSVDDEQDLEALLTQYFRRKIRKGEYEFSFAHNGLEALR
                     MMLDHPDFDIILSDINMPEMDGLTLLTKINEMRNPALKCIIVSAYGDMENIRTAMNHG
                     AFDFATKPIDMEDLERTIEKAVEQISFIKEAQKEHHQLEEIQYDLNVAREIQQSILPK
                     QFPPFPQYKQFDLYATMSAAKAVGGDFYDFFLVDDNHLGFTIADVSDKGIPAAIFMAI
                     SRTVIRATALRQLSPAVCMKESNDLLCRESVNGMFVTTFYAILNIHTGDVVYCNGGHN
                     RPVWIRKNDKVSLLPMTGGMALGVVPGLAYKEQSLKLEAGDSLFLYTDGISEAMNLRN
                     EQYGDIRLVEACSSVKNQSPKAMIEGISESVQSFVNGATQSDDITMLALTYKGQIL"
     gene            complement(49296..50147)
                     /locus_tag="ACZPB4_02450"
     CDS             complement(49296..50147)
                     /locus_tag="ACZPB4_02450"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1097117.1"
                     /translation="MEDQSKEIERLRLQVKNLEKLSSLGMLSAGIAHEIQNPLNFVIN
                     FSKLSSKLVDDLEDILEEEKDVLPPESWEKLTALHEEFSEIVNDLHGNLKKIEEHGNR
                     ATSIIRGILLYSRGKDDEYIPTDIKNLVKEYVWLAYHSMRANYKGFNIAIREHYEEGL
                     PMLKVIPQDLSRAVLNVMNNACYAVYSKSKLSPIGYEPVISVDLRKEGDSLRLSIEDN
                     GIGMPEDIREQIFSAFFTTKPVGEGTGLGLSITRSIIEEKHDGKIEVESKEGEFTRFI
                     FLIPLTK"
     gene            complement(50150..51280)
                     /locus_tag="ACZPB4_02455"
     CDS             complement(50150..51280)
                     /locus_tag="ACZPB4_02455"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1097118.1"
                     /translation="MIQDLHTEIDRLKRRIKLCERVTLGSLVGICVSVKFGHQEWIGL
                     LFLILFCQISKLVFKRKLKQKEYLVKEVEERTQEIRSEKDAIQEESEKLAAALKALGE
                     AQDELVRKERMATVGQLTQGLVDRILNPLNYINNFANLTSGLAKDLRENLDSQKEHLK
                     PDVYDDSVDLLNMMTSNLEKISEHGFNTVRIVKAMEELLKDRRGNLTLTNINGLCRIA
                     LDKLKKTYEQDIQEKNIRIVFDNLTLSLMMEVNVEQFSKVLAGILKNSMYALLKKSET
                     VTFSPEIFLGLKVNKDMLEITIRDNGSGIDENIKDKIFAPFFTTKTTGEAAGVGLYLC
                     REIVQNHRGTIEVESKKGEYTQFLITIPVYQPKTITPPKEEE"
     gene            complement(51296..52396)
                     /locus_tag="ACZPB4_02460"
     CDS             complement(51296..52396)
                     /locus_tag="ACZPB4_02460"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1097119.1"
                     /translation="MGDINIKQLESLRWRMRVIETLTVIGTAWIALAVYQKKEELVYY
                     LVGAVVLLFLLKYYTQFRLRKRQFVSNLVEQRTMELRFQRDAMQAESEKLSRALSALA
                     DAQDELVRKERLASIGQLTKGLVDRILNPLNYINNFAHLSAALAKDIKQNIDEDEETG
                     KHDNYNDTQELLVLLTGNLDKIAKHGDNTVRIVKAMEELLKDHSANRTCVDINDLCKV
                     NLDILRKNYAKEIEKNQVDLSFSGLSVPLTIEVNIDQMGKALLQILDNSIYAVLKKLG
                     EPGYQPSVSLVLRIQADKLQVVIRDNGVGIEETIKTKVFSPFFTTKPTAEAAGTGLYL
                     SREVVLNHKGTIAIESEKDKYTEVTITLPIYS"
     gene            complement(52416..54200)
                     /locus_tag="ACZPB4_02465"
     CDS             complement(52416..54200)
                     /locus_tag="ACZPB4_02465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HIR1097120.1"
                     /translation="MKTIYNVKALCVVALLGSAAAASAQEDVTKEKNLNREMTLEREY
                     DPSVQDASKVNTLPVVKEPEVRKIPIDYSNYTIAADPQKEISLLPSGNIMTQMDYNKR
                     RGYFNFGMGTRMNINGDLGYHILSTEKDQLNLWYSHRSTNGKPKDYDVKAKINDNLGG
                     INYKHAFEKTIFSIGAKYGYSAFNYYGAALSDPTSSYAPSEDLLQRDRETNQVNQTIA
                     ATIGFESKEEAEVGYLLDLGYTNFSHKYGLSRVMDGPTEHTLEAKFDLNAGFNGNMRV
                     GLGGLVEYFNYSLPEVGGYEYEFKNHVEAMLSPYYKVEGDNWNLKLGANVMLATGDET
                     KFMASPNVAADVEVADKTELYVNAGGKMYSNSMYEMSRVNRYLYPMAELLPSRNWLDA
                     VLGIRSGVVPGFWFDVFAGYKITSDDVLFTQSDVWSANYFGSFSVAEPGIDTKQLFVG
                     ANLKYSYQQWFDIALKGVYNNWKAETDEGELPHAWGKPEMELNANLTVRPIEKLSIAL
                     DYYLATGRYANVRTWGVNGNTGMTYDKMNEFKMDNINELNLTGTYTFNDTFGVYAKLT
                     NILCQKYELYYGYPMQSFNAMLGVNINF"
     gene            complement(54210..57209)
                     /locus_tag="ACZPB4_02470"
     CDS             complement(54210..57209)
                     /locus_tag="ACZPB4_02470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HIR1097121.1"
                     /translation="MKRILIPLCLVVGSHMASGQRSYQFDAPNRLFVEGKELFSLKNY
                     SGCIDKLEAYKQHSTDADLIQEADYMLVYSAYEQGRPNAVELLKDYLDVYPASRHADE
                     VNFLIGSAHFGQGEYQKAIFWFNESNIDMLSPEQQEAYCFRLAYSLLQIGDMEKARGY
                     FARIEQIGTKYREASTYYVAYIDYATGKYNNALVEFTRLKDLPDYKERSLYYITQIYF
                     IQNKYEKVISEGKELLASYPDSENNSEVYRIMGNAYYHLGNEDQAINMLSKYVSSTDS
                     PLRGDLYILGVCYYNKGNYSSAVNALGRTVRENDALSQNAYLYLGQSYLKLKDKNNAR
                     MAFEAAATSSFDKQVKEAAMYNYALLIHETAFTGFGESVTIFEDFLNDFPNSKYADKV
                     NDYLVEVYLTTKNYQAALNSIDKIKHPSTKILEAKQDILFQLGTQAFTNMELDKAVDL
                     FSRAISLGAYNLESRNDAYFWRGESYYRQGEYNKAISDYRTYLNNTRQRNTDMYALAH
                     YNLGYSYFKLKEYGEALNRFRQYVNLESNQQTPAYADAYNRIGDCLFHNRQFAMAEEN
                     YTRAAQLQPSAGDYSVYQKGFLLGLQKDYKGKISVMDRLIREFPESQYVDDALFEKGR
                     SYVLLDNNQAAAASFEQLMRDFPQSSLARKAGVQLGLIYFNDNQPEKAADAYKSVISN
                     YPGSEEAKVALQDLKSVYIELNDINSFAAYANSLGGNVRFEVSEQDSLTYLAAEKLFM
                     RGDNEGARRSLTNYLQTFPQGAFSSNANFYLASIAFAKKDLEEAKRLFSLVLESGDTK
                     FREESWARKAEIEYLDKDYAAAMESFKHLQAVAENPENKEAAKLGLMRCAELTGQPQE
                     ALLAANDLLKEPKLSPEIMSEARYVRAKAYISLKQENKALADLKEISKDTRTIHGAEA
                     KYLLAQLYYDNKDDKNAETVLMNFIENGTPHQYWLARGFILLADIYIRQGDDFQARQY
                     LTSLQNNYKGDDEIAAMIEDRLGKLKK"
     gene            complement(57456..57974)
                     /locus_tag="ACZPB4_02475"
     CDS             complement(57456..57974)
                     /locus_tag="ACZPB4_02475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012056082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HIR1097122.1"
                     /translation="MRHPLYQFQFCPVCGAKAFVEHNEKAKKCMACGFVYYFNPSSAV
                     ACFIKNAKGELLLVRRGKEPAKGTLDLPGGFVDMFESGEEAARREVREETGLHIQNCR
                     YLFSLPNLYMYSGFEVHTLDMFYECLVDDFNNVHAEDDAAEIVILRPENVNPEDFGLD
                     SIRKAVPAYLRK"
     gene            complement(58078..59064)
                     /locus_tag="ACZPB4_02480"
     CDS             complement(58078..59064)
                     /locus_tag="ACZPB4_02480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HIR1097123.1"
                     /translation="MEKPYVVGIDIGGTNTVFGVVDARGTILYSGSIKTGKYADVNDY
                     VAELAKGLKSVIDQAGGPDKIKGVGVGAPNGNFFNGCIEFAPNLPWKGKIPLAQLISE
                     QIDGIPVALTNDANAAAIGEMTYGAARGMKDFIVITLGTGVGSGIVIGGNLVYGHDGF
                     AGELGHVIMRRNNGRQCGCGRQGCLEAYASATGVARTAREYLEIRKDESVLRDLDPDE
                     ITSKDVYDAAMKNDKIALEIFEATGSMLGEAFADFVAFSSPEAIILFGGLTKAGDLIM
                     NPIKRSMEKNMLKVYAGKTKLLFSQLKESDAAVLGASALGWEVRDQSAGLEV"
     gene            complement(59233..59610)
                     /locus_tag="ACZPB4_02485"
     CDS             complement(59233..59610)
                     /locus_tag="ACZPB4_02485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HIR1097124.1"
                     /translation="MEVKGRFDHFNINVLDLDKSIAFYNKALGLKEHHRKVAEDGSFI
                     LVYLTDEQTGFLMELTWLRDRKEPYELGDNESHLCFRVAGDYEEVRKYHKEMGAVCFE
                     NTKMGLYFINDPDDYWIEILPLR"
     gene            complement(59658..60380)
                     /locus_tag="ACZPB4_02490"
     CDS             complement(59658..60380)
                     /locus_tag="ACZPB4_02490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HIR1097125.1"
                     /translation="MRLVYIYHSGFALEADGFSILIDYFKDSDPDPAKGYVRSELLKR
                     AGTLYILASHFHPDHFHPEVLKWKEQKPDIKYIFSKDILKRRRAKADDAIYLKKGDAY
                     QDELLTIKAFGSTDVGISFLIETEGRRIFHAGDLNNWHWKDESTPQEVAEAEGNYLKE
                     LDIIAKETSVMDLVMFPVDPRLGTDFMRGAQQFIDRIKTSVFVPMHFWERPAEVMAFG
                     PYAESKGCRYIVLSVPGEGTDI"
     gene            complement(60507..62381)
                     /locus_tag="ACZPB4_02495"
     CDS             complement(60507..62381)
                     /locus_tag="ACZPB4_02495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0019867 - outer membrane [Evidence IEA];
                     GO_function: GO:2001070 - starch binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RagB/SusD family nutrient uptake outer membrane
                     protein"
                     /protein_id="HIR1097126.1"
                     /translation="MKKVLIYFAMAVVLALGSTSCSDFLEIEPVGAVNETNLTDQEGI
                     NYLLTGMYSALNIPAATTNSYFGASLTNYTYGDVMGGDANKGSTAADQSDFTLLETFS
                     FTTDNSYIKRKWVAVYDAVARANNVMHLAGLIKDELSAIPGQEKDFYTEAIAQARFMR
                     GFYLFEGIKNFGAAIPYVSLEDYESSVNPLISNVDESGNYIYIWEQVAEDLQYAYDNL
                     PGAWPEEPGRANKWAAGAFLAKLRIFQSSPYNGTNGTSNKWTEAKSILETVIANGTDS
                     KGTKYTLTPSYETLYTAGESDWTGESVFDVQMAISGTQYYTNAINGNSHISLSGKIGS
                     GWGFYQPSYDLVNAHMVDENGLPYLDKSYQSKTSVTTIDGDNVPHTDLTVYTDPRVDV
                     SAGRFNVPYMDWDIPVTIDGWIRDLANGGPFLNKKNLPKKADKGGLSLTTTGGSTAKN
                     FHLMRVAELYLLYAEACIETGDINTAREYINKVRARAAQSCIMAADANNNMALTSSPY
                     VLEDKVSGNTIANTAANYRIGLYPASGWTVDKAIKALRFERRIELAMEGHHWYDLVRW
                     NAASEELGNKGSGFLAYEKRYLLKYQSATYPDRLVTLPIPNDEIVTMEGVLVQNENWK
                     "
     gene            complement(62418..65801)
                     /locus_tag="ACZPB4_02500"
     CDS             complement(62418..65801)
                     /locus_tag="ACZPB4_02500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SusC/RagA family TonB-linked outer membrane
                     protein"
                     /protein_id="HIR1097127.1"
                     /translation="MSNVVFWRQVFLGASLFLCGGYPIIAAEVGDLTPNVGTRSLQQD
                     GRRVICAISDKAGPIVGANVLVKGTTIGNISDMDGRVILEGVPSNAILVVSYIGYVSQ
                     EIPLKSSQTNVRIQLVEDTQALDEVVVVGYGTQSKKDITGSVAVVSTDAIHETPVATF
                     AEALQGKASGVYISNSGGPSGETTIRIRGVGSLNSSDPLIVVDGVSGVDISSVNPNDI
                     ESMQVLKDASATAIYGAQGANGVIIITTKQGTRADRVRVSYNGYFGVAKMANSGYDLL
                     NGWESMEFEELGQQNLYNYRGLATSHPQFGQIAATGGKGISMPYAIKPAGYSEQQIID
                     MYGSVEAWEKSYVDDGSSSWARSAYYQMLADGYSDAEARKGTNWYDEIVQTGKIQDHQ
                     ISLVGGGEKATYSVSLGYTNREGTIQNSYFKRYSLRTNTTYNPNKYFTMGQNTNLAAM
                     ETGGESGRQGDANTFAKTYTMNSWVPIYNVGGDYTGSVAPNAGRDISAVHQVAMNEND
                     WTRMFHGQTAVFAELSNPWIEGLKLRSQFSARLNGMWSLEMTERQNMANKEASANNTL
                     TETGNWRLNWQWTNTATYTKKIHEDHNITVVLGTEAIKQGVGRYMQGTRIDYIFESDP
                     NTWTLDNGSSSNIGNSSRYQRKVTMFGLFGRADYSYKGKYLATFTIRRDASSKFGSKN
                     RWGNFPSASLGWRMSDEKFMEPTRKWLDDFKLRAGYGTTGNSNIGSYNYAFQYGTGNY
                     YMYPITGSDSETSPGYVLSNLGDSDAKWETTKMFNIGFDLTALSNRLTAGFDFYVKNT
                     SDLLVPANWSALVGNASKPSINIGDMKNRGVDLSIGWRDKVGEFGYNITANISRYKNE
                     VTRLGSSDLFNDTRLSKVNITTVGQPVGMFYGYQIEGIYQNEQDVISSGVLPYGVATE
                     NDLVASAWVGRYKMKDVNNDGKIDADDRTIIGNPHPDLTGGFNISLTWRDFDLSTYMY
                     YSIGNDLYKHYEYYTMFGNLQSNYSKDRLAKSWDPVNNPNGIYPLWTTTSTEGPEAGN
                     ESNSNYVQDGSYLRMQTLTLGYSLPKKLLKKIGFEKIRVYGQISNVFTITGYDGLDPE
                     VRSHTSFENEYVSSDMNKGIDYGSYGMPRQFLMGVNVTF"
     gene            66360..>69639
                     /locus_tag="ACZPB4_02505"
     CDS             66360..>69639
                     /locus_tag="ACZPB4_02505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SusC/RagA family TonB-linked outer membrane
                     protein"
                     /protein_id="HIR1097128.1"
                     /translation="MRNVVSWKPLVLGASFLLYGAGTAFATETDHLYPTPSTGFMSVQ
                     QDGRQINCHIVDKSGPIVGANVVVKGTTIGNISDMDGRAIIENVPANAILVVSYIGYV
                     TQEVTLKSNQTNIKITLVEDSQALDEVVVTGYSTQAKKDITGSVAVVATDELKETPVS
                     NFAEALQGKAAGVFVQAGGGPLGETTIRIRGVGSVNGSDPLIIVDGVQGVDIDAVNAN
                     DIESMQILKDAAASAIYGAKGANGVIVITTKQGKKNDRVQVSYNGYFGVAKMANDGYG
                     LLNAWEAMEFQEEGQRNLFNYRGGQTVNHAQFGSIGKDGTGHLTMPYAIKPAGYSKEQ
                     IISQYGSIAAWEASYKDNGENTWSRSAYYQMLEDGYSEEEARAGTNWYDEVVQTGKVQ
                     DHQISITGGGEKATYSVGLGYMNREGTIKESWFRRYSLRANTNFFVNKWFNIGQNTNI
                     AVIENSGERGRQGDDNTFGKTFSIQPWVPIYTVGGDYSGSQNAEGGRAESAPMSVDYG
                     KDNRRRFLRAQSAIYAEIMPLESLGENLKIRTQFSARLGGAWDFWMNKRTIMTNKEGR
                     NNNEFYEQANYWLDYQWTNTATYSKTINDDHTINAVIGTEALREGLGRWIQAGRINYP
                     FEDDPNTWVINNGASSDLRNSGNQNAVSTMFGMFARADYAYQGKYLATVTVRRDASSR
                     FSEKNRWGTFPSISLGWRMSDEKFMEKSRTWLDDLKIRAGYGTTGNSNIDSYNWAFQY
                     GTGNRYLYSINGSDTEVYQGFGVTNLGDIEAKWETSKMFNAGFDITAFNQRLTANFDY
                     YIKKTSDMLIDANWSALAGAADKPKVNIGDMTNKGVDLNITWNDKIGEVGYSVGVNLS
                     HYKNRLDEIGTDAGIFTGTRISNMNVLMKGHAIGEFHGYQLDGIYKSEEEVRNYKNDA
                     GGTVLPYGTSDASTLNAANYVGQFKVKDVNNDGKIDASDRTFIGNPHPDLTGGINLGV
                     NWKGFDLSTYMYFSVGNDLFAMYKYYTHYGSLQSAYSKDRRDNSWHPVTNPDGIYPMW
                     ATANGESTIAANESNSGYIEDGSFLRMQTLTLGYTLPKSILDKIKFEKIRIYGQIANV
                     FTLTG"
BASE COUNT        21010 a        16887 c        12850 g        18892 t
ORIGIN      
        1 caagatgtat ttccataacg tgaatgattt agtaggtgct tacaatctgc aaggaatttc
       61 acggattcag cgccgacaag ttagcgatta tccaaatccc aaccaattat cattccatgt
      121 ttagaagcat aaaaaagccc ccgtctctct catcctccct aagggaaaga aagacggggg
      181 cataattata attgttcagt agtagaagtt tttcctgatc cattaggacc agcaacaata
      241 caaagtgtag ggcgtttctc tttcattaca aatcactatt tagattcgtt cgatctatat
      301 atcttcagtt tttctctcac ttcctgcatt cttcgtttca gttccatctc cgctctaagt
      361 gaactttctc gagcggcaat agctacttgc tccattatat ctttcctatc atgaagtaac
      421 tttaattaaa tgaatagatt atcaattaaa tcttcgctct atcaatccaa ttctctattt
      481 taagatgagg aatacgttct aggtgcttta cattttctgt aactaaaatc aaatcatttg
      541 ctacggcaga agctccaatc aacaaatcaa aatcatctat taaaagtcct tgagatctca
      601 atgtgctttt tagttcagcg aacataagca aagaaccgta aattggtaaa actgtaaact
      661 gcgagataaa agattctacc tctttcaaca ttttatcctt tcgatttgag caagtagctc
      721 catatagaag ttcggcaata gtaatttcag aaataaagca atatcgcttc attttatcat
      781 caatcttctc atttaaatga aatttccctt tcatatagaa gatacatatg ttggtatcta
      841 aaagataacg cctcattcgt caaaagattc aatagatcgc gttcccaaaa cacgtgcttt
      901 attaatttca gcaataatct cttctgcact tttgtcatca tcccaagcgc caaacgaatc
      961 ttgtatggat gtctctttct ttttacccct caaaaggctc tctgaaagct tacgaatgac
     1021 acgcaacttt atctcatcgc taaacgaaga caataaattt atataactat ccgctatttt
     1081 caccgttgta tccataatct ttttctttta cagaaacaaa tataatcatt attgattata
     1141 atacagtatt tagtctactt tttttgcaag cgtgaaccac caatacagcg tacccagtat
     1201 ttatcaacag gttaaccata ccagtttttc tgaacaaaat tcagatttct tattctttaa
     1261 caattaagcg gctgtttgag acggctttgt tatctcagca tccttgccgt ctccataacg
     1321 acgaacatag tcacatggca agaacaaagc gtccacattg ttcaacttgc aactttctac
     1381 caaacacaaa aaaaggtgca tcaaaatgac acaccctcct cgtaacaaaa ataaaatctt
     1441 tatgattagc ctctacttag gcctacacag taaaacgaat ttaactcatg gaatagctgt
     1501 taaaatcaac gctcaatcaa gccccttata cctccaacga tatactcaat atcccgatcc
     1561 gttacatacg ggccggaagg caggcacaac ccaaccttaa acaaagattc gctcacccca
     1621 ttcacataag ccgggcaatc tttatagaca ggttgcttat gcatcggttt ccacaaagga
     1681 cgggattcta tacccatcgc gtcaagtccc acacgcatcg cctcgacatt ggcattcggc
     1741 tcgcaatccg tatgtgcgtt aaccgctgcg tgagtcacac cgcccgcacc accaacagca
     1801 ccttgtacca ttgcttgata agcattctcc tgccctttca ccctcaataa aggatccaag
     1861 acaatcgtat tcaaccaata attactatca aaacgaccgg aaggattctc atgcaaggta
     1921 atccctctca catccttcaa cagctcccga tataaatcac acgtatgctt atgatgagcc
     1981 acatgagcat cagccaccgt catctgacca cgcccgatac ccgcacaaat attcgacatc
     2041 cgataattat acccgatccg ctcatgctgg taatacggat aagcctcccg agcctgcgta
     2101 gcgtagaaca tgatctcccg cttagcctcc ccgtccggac aaatcaacgc accaccacca
     2161 ctggtcgtaa tcatcttatt cccattgaac gacagcaccc catattttcc aaacgtaccc
     2221 aacatacgtc catcataacg agagccaaaa ccctccgccg catcctcaat gaccggaatc
     2281 ccataccgat cagcgaccgc cataatctca tccaccttat aaggcatccc atataaggcc
     2341 accgggacaa tcgctttcgg tgtttttccc gtcttctcga tacgatcttg aatcgcctct
     2401 tccaacaaca caggatccat attccaagta tccacctccg agtccacgaa cacaggcgta
     2461 gcccccaaat aagtgatcgg atgcgaggaa gcacagaagg taaagctctg taccagcacc
     2521 tcatcctccg gcttcacgcc acaggcaagc aacgccaaat gcaccgcagc agtaccggca
     2581 gacagagcca ccacatgttt accttcaccc acgaattcct ccaaatcttt ctcaaatcca
     2641 ttcacgttcg gacctagagg cacgacccag ttcgtatcaa aggcttcttt gatatacatt
     2701 tgttctttgc cgctcatgtg agcaaggcaa agataaattc gtttattcat tattattgtg
     2761 attttagaaa atacttcgga tcagcataaa agcctcagct ctttctacgc taattgtagc
     2821 acctctatat ttcgccaaag cttccaaagc ctctaaagaa cgagaactag ggaaccgcct
     2881 tagttgagat tgataacact ccatcgctct caatttcatt ttcattccat cttgactaca
     2941 aggaatgaat accgtgggaa taaaagcatc atccgcataa ggagcagccc attcagtttc
     3001 agataacgtt tcataggtat aaactcgctt aaccgtataa tctccaacag gacgacaagc
     3061 gactaataca ctgtcaaaga ccatccgatg atctttatgt atatctcctc tatggggaat
     3121 aaacactgta tctatttgat tttcggatat acattttgaa acttcacgag acatgatata
     3181 acctggatat tgatctaatg caggagccgg aaaatcaaag aaaaaggtct gttttacacc
     3241 tagtaaacga tgagcctcca gtgcctctgt tctaacacgc tgaatacctt tttcggaaaa
     3301 aatatttgga tcagatttac tggcatttgt cataatcagc acatacacat tatgaccttc
     3361 ttgcatcatt ttataaatag ttgccccaca gcccaatatt tcatcatccg catgaggtgc
     3421 aacaaccaat atattcttaa acacgactac ttagttaaat atttattaat aatattataa
     3481 acatattcaa tctcattctt cccataacgc tgatcaatcg gtatagggat catataagag
     3541 gatagataat actcaaaaga tgtagaatca gtttccttaa gcaaataatt ccaccaacgt
     3601 ccggtataaa ttttctcttt acttaaaaga tccaccatat cagatttctc tacaactaat
     3661 ggataaacaa atggaacaca attatcatcg aaatatatat gaggattgat tttattcata
     3721 gaagaatata aatcagatgc taaattaaaa ttctcaaatc ttttattttt aatataatca
     3781 taaggagcat ttttaagtat agcacgagaa agaatagaca ttctagaaat gttagacata
     3841 tctatacgct tctcatttaa ttgtctatat tgataagcag aattgcaacc cacttctatt
     3901 ctttgtaata agaaacctgc tgtctcagaa gataaatctt gatcatattc atcactaaac
     3961 cttacagcat ctgggcctac tacataacag ccatcaggaa cgcctacaaa ctttctggga
     4021 gaatagacat tatagactcc atttataggt tttgcgaata gagattgggc attgtcgatg
     4081 ataacatttt tatacccctc aatcaatgat aacatgtgct ctgtagacat aaggccaaaa
     4141 taattcacaa acactattgc ggtatcatca tcttgagaaa tatcaagagg cataaaatcc
     4201 ttatctatat gataataatc aactttaaaa cctttaccaa gaagaaaatt acgaaccgta
     4261 aagcactcat aataaggcaa aaggacttta tttacattta gaagtctaca acaatgataa
     4321 ataccagctc tattaagatt taacctacag acttcagagc cattaaacaa ctcaccagta
     4381 tcacgtaagt ctaattccaa aaaactacct atttccattt atagcatcaa ccttatcaac
     4441 tacatactca aaatcaaatc cacaattaaa aatataatca agaacagaca tattctctat
     4501 aaaatctccc cataactgag gatactcaat aggagaataa tccatatatt ctaattttaa
     4561 tcctctttca ttaaaatggg attcatcttg atacactcta gcaccattgc ccgaaatata
     4621 tgcagtagct ccaacttcca atgacaaatc aattacacgc tcctcttttt tagcatgaga
     4681 aagcaattca gaggatctaa atattttagg tttaatacca aattgattgg agataaatgt
     4741 atttaatgct atattcaaat ctgccacatt ggaataatca tttagatata cctcttttaa
     4801 agatggataa atatcagaaa agaaaggagc tttcttataa ttcatctcta ttgtcttaag
     4861 atgctttccc ttccatttca attcatcttt cggtctcaca tgattaatag gatcaccaaa
     4921 tttcatttct acgggaaact ttacacgcaa gacaccttga ggggtcttga tcttattaaa
     4981 attgtgagca gcctcattcg agaactgagc atcatccaag tatataaaca aatcagattt
     5041 atacatcttg taaaagaatc ccaaatatgg aatataatca ggctgatgta ttgctacttt
     5101 cataagcatt atttttttcg gttctttctt cagataaaga ctttcttaca tattcgccat
     5161 aattatcatt tttcctatgg attaaaagtc taaacgttct aaacaatatt tttaaatcaa
     5221 taaagaagga gcaatcttca ccatactccg cttcccactg tagttgttca tcccaagttg
     5281 gagtaggatt atcctttaaa acttcaggag gtaacaaacc tccccttact ttaaatcttt
     5341 ttttctcata atcagaaaaa tatatattgt atttagaagg cattggtctt ggccctatga
     5401 tagtcatgtc tcctttcaaa atatttaata actctggtaa ctcatctaaa ctggtatttc
     5461 gcaaccaact gccaaatgaa gtttttctca gttcatccgg caaaagattc ccatctgaat
     5521 cagttttatt agtcattgtc ctaaatttca ataaactaaa agaacgtcca ttcaaagttg
     5581 aacgctcttg tataaagaaa attggagatc ctaatttaaa ccgaatcact actattagaa
     5641 ctaaatatat gggaatcaaa gctacaatgc caaacaatga taaaataaaa tctattatcc
     5701 tttttatata tctatacatc atactactat atataaaaac atactcagat tatttttttt
     5761 cactttcctt atttttcacc aaagttccaa aattaacaat ctggcttttc tcgcttatct
     5821 ctattcctgt cctaataatc cgagctggat ttcccgcaat aagacaatga ctaggaaaac
     5881 ttttcgtaac tacactacca gctcccacaa acacatgatc ccctaatgtt acgcctggag
     5941 taattattgc tcttccacca atgacacatc tctttcctat atatgtatca actttatttt
     6001 tacccctaaa ataatcatga gccaataaca taaccccaac cgacaccctt gtctcatctc
     6061 caatatgaat acccctagga tttactttgt ccatatctat cctctgagaa atagagacgc
     6121 cttttcctat atcaactttt ttgacatatt tcaaataatt ggtatatata ccacgaacta
     6181 ccttactaac tctttgccga aatgttttct tttccatata actttaatat taaattatca
     6241 cctatcaact taatcttaaa tgcttacaag cgttgacaca atcataggtt tcgtcttcac
     6301 ccacatcgtc ccccaactca atcccagtcc aaacgaagac attaatagtg tcgtttcttt
     6361 agtcctaagt tgatctgcga tccttgttac catcaatgaa ggaatagaag cacctcctaa
     6421 gttcccaaac tcttccaaat tgtaaggcac tttctctttg ggcaacttca atttcttcac
     6481 gatacgatcc acgatcatct tgttcgcctg atgaatcaag aaataatcta tatctgtttc
     6541 acgattgata ttataatccg ctaagaaagc ctcaacggat ttaggaggac gagatatggc
     6601 aaatgagaaa acattcatac catttatcaa cgtatgaata ggcgcacgca caataccatt
     6661 accaaaatcc tcatattcaa aagaggcagg agtagccgga tgacgaaaac caccatgagg
     6721 ggtcatcaga gcctcatatc cttttccgta ggtatggaag tctactacaa tatcgttagc
     6781 gacctcatca tattccaatg cgatcgccgt accacaatct ccaaataaag gtacacggct
     6841 tttgtctttc atggaaccca ttcgcaaggc cgtatcccct ataagtagta acgcacgctt
     6901 cacattaccc gccgtcaaca gattaccggc aaccgttatg gcatacatac aaccacagca
     6961 tcccatgggt atgtccatac agaaacaatt ttccgacaag ccaagcctat cctgtagcac
     7021 acaagaggtc gggggagtac gataatcgcc tgtaacagac tctaacaaca atacatcgat
     7081 actatctttc tcccacccta actctacaag cagtttttca gcggcagcct gacacatatc
     7141 cgaagcgcac atggtatccg gggctatatg cctacgtttt ataccaaccg tattgtcgaa
     7201 cacatccgct tcctcttgag aaagaagtcc taattcggaa gttgttacca cattcttagg
     7261 aacagccata gccactcctt tcatgccaac attcttaatt tcccaccttg ccataagtcc
     7321 aaccgttaaa gctcaacatc gtacttcttc aagatctcac gtcctttacc atatgaggta
     7381 aattccatga tatcttccgg gtcaaacata atatccaaag actcttccaa taaagcgatt
     7441 atattcaatt gatgaacaga atcccacgca tccacgctgt cttttgaaaa gccatcatcc
     7501 aacaccgcga tctccacacc aaacacttct acaaaagcat tattatactt ctctatattt
     7561 gtcatagcta tttactttta tgaatttaac ttactataca atatctttcc cgcctcattc
     7621 ttgggaattt catcaatcac ttttatctca aatgccgagg ccaccaattt ggttttttct
     7681 accaacacct cttttaccac catcgcatat cgctcatcag tcaagtaaac ggtcatcttc
     7741 tcatccgtac ctacgcaagc acattctatc ggatattttc ctttgattat ctgctcgcac
     7801 tcatccaatc cgatgcgcat accgaacagt ttcaagaaac gtcccatgct ccccactatg
     7861 tagtaacagc catcctcatc ccgataagcc aaatcaccgg tacgcataaa accattgcgt
     7921 tcatcaccca gcgacaggtc ttcccgacta cgggcatatc ccatcgtcac atttttacct
     7981 cgataacaca tctcaccttc ggtattggcc ccctctatac gatttccctc actatctatc
     8041 aacgacaact ccgcattagg tacagcccgg cctatactgc cgactttctc aatggcccat
     8101 tccgcaggta aataagccat acgagcagtc ccctccgatt gtccataagt cgcgatccag
     8161 cgtttcccgt tgtcacgaca atattcggca aacttcaaat tcaactgacg agacatttta
     8221 ccaccacctt gagtaagtaa ggtcagatcc ggcaaatcca tccggaaaaa gcgcattaag
     8281 ttcaatatct caaaactgta aggcactccc gtaaaactag ttgcccgttg ttccttcata
     8341 aagttccaaa aagccttgtc cgtcatgctc tgattcgtta tcaatacagt agagcccaca
     8401 tacaaatgac tgaatacgac tgacaatccc atcgtataat acaaaggcaa caccagtaag
     8461 ggcctgtcat cagacgtaag tccaaagaaa gtcgatatat tcaaagctgc cgcctctata
     8521 ttctcatact tatggcgtac caacttagga cttcccgtag agccggaagt aggtaacaag
     8581 tgagacaagt cggcatgtag cgtacaaggc tccatacctg tatgcaacaa tgtatagcca
     8641 tagcactcac acacgatctc atatcgcaat gcggatgcca ttcttgtagg aagacacaca
     8701 taagagggac ggtatatttc aaacaaatta tgataaagcc cctcctcgat atgagcgttc
     8761 aatatcaaag gcacattacc cgaatgaata gaccccatgc cccacgctat tccccccaca
     8821 ttgttttctg tcaacagaaa caataaggaa cgtactggaa gcaaagagcc gatcctctct
     8881 gaaaaggata acaattcccc atacctcaag acagcccccg aagcatctat tgcggcaacc
     8941 gcatcctgcg gtcgctcatt caaacctaat atcatctgat tattttattc taaatggaag
     9001 cgcaaccatc cacgcccaat atctgaccgg aaatatagga agccctgtca gaggcaagaa
     9061 aagcacaagc gttcgccaca tcttccggtg tacccaaacg tcccaaagct attttctgaa
     9121 tacgtgtatc aatcttctca ccactctcct catacaattc agagaatcgt tccgtcttca
     9181 cgatacccgg cgctacggca ttgactctaa ttcccaaagg agctaattcc ttagcagctg
     9241 atttggtaaa cgacataata gcccctttgg tagccgagta ggcagactga ccgggagacc
     9301 ccaatactgc cgtaacagat gcgatattca caatcgatcc accaccatta cgagccatta
     9361 aacgagatac caactgtacc atttctatga ctgcaatcac atttacccgg aacatctgtt
     9421 ctgtttccgg tcgaacaatc atgccgattt tcttattaaa caccacaccg gcattattaa
     9481 ccagtacatc aatacgacct tctcgtttga atatcgacat aaaagcagac ttgacagctg
     9541 cagcatccgt cacatcaaaa tacaacggta ttacaccgat tccttgtaca gccacacatt
     9601 gttccgccca tacatccata cttccttctt gtaggtcaca agcatataca atagcaccat
     9661 caccgacaaa acgttctgct atcgattttc cgataccctg tgcagcaccg gtaatgatac
     9721 atactttatt ctctaaaaat cttcccatct ctattatttc aagctacgtc ctccatcaat
     9781 cactaaatgg gtacctgtaa cccataatga agcatccgac aataaataga taatagcatg
     9841 agccacctct tcgggctttc catagcgttt taacgggtac acgtcgatat ctttagctac
     9901 atcttccatt gtcaaaagtt tattttctat caatggtgtc tgaatccttc cgggatgcac
     9961 agcattgcaa cgaataccct taccggccaa ttctaaagcc gcatacttca tataagtact
    10021 caaagcgctc tttgaagccc cataaattcc attggcagga gccacattac cataagcgga
    10081 aatagaagcc gtaaaaacta ccgaagatgg attcttcatc tttctttttc gtaccaataa
    10141 tttcatgaga agcatgggtg caaatacatt gactccaaat acttcctcca atacttcaga
    10201 cgaatagaac tgtacaggaa tcatctttcc tataccggca ttacagacaa agccatccaa
    10261 cataggcaaa gaagcaatca attcaccaca ttcgtcctcc ttagacaaat cagcgacaat
    10321 gaaccgatgt tcctttcctc cttcaagagt ttgaagcgtt tcatgcaaat tttgtacgtt
    10381 ccggcctgtc agtattagag ttgcacccaa tttagcgcac tctatagccg ttgccctacc
    10441 gatgccggaa gaagcacccg ttacaagtat cgtcttacct tctaaagaaa aaggattata
    10501 cattacagac gagaagatac caaattatac aaatcgccaa tggttacctg tttcttcatg
    10561 tcatcacccg taaccgtcac attatattct tcatcaatca tggagataat catcagagcc
    10621 accaaggaag tataatcatc caactcatga aacttagttt cagtagtcaa taaaccagca
    10681 tctacatcat caaattgttc agccaatttc tcgataaaat cagtcatttc catattctta
    10741 tttatttagc ttttacatta atttcttagc cggattcccc attacagttg taccttcttt
    10801 tacacgcctt ataacaaagc tacatgcacc cacatgtgcc ctatcttcaa ctacaactcc
    10861 atgattcaag acagaagaag tataaatatc cgcttcattc cctattaccg ttcctcccac
    10921 acaggtaaca tgggtatcaa cccggttcca gtctcccatc tgtacatcat gtcctattac
    10981 cgtataagat tgtatcaaat tataactacc aatctttgca tctgccccaa tactggtgta
    11041 cgctccaact atatttccta cacctaattt cacatttgtt ccaatacgtg ccgtgcgatg
    11101 aattagactt ataaataaag cacccttatt tataagctct tccatacatt tcttgcgaat
    11161 tgccccacct atagaacata caaaaacatc atctttttgt ggaatataag tacttattct
    11221 atctaaaata ggaggatagt ttgtaaaacc atctaaagca tagaggttgt catctataaa
    11281 tcctttcaca acaaactcct cgccataccc cctactctca cgagacatgt catataaagt
    11341 acgtcccatg cctccagcgg caatgattat gagatttttc ataacgctta gcttataaat
    11401 caatattctt tgatcaaaat catctataac tcacttaata aatttcaacc tcaaacaact
    11461 cctcaaaata aaatacaata gtttaggaga aacatacaat aacataaaat aatatttagc
    11521 aggactactc cacgaagtca tccgtaccct ttcctttata tactttcgca ctaaagaatc
    11581 tgtatataca taatcaacta aatcacgagc cttacctagt gctacaactt tcacatactt
    11641 attaaaaaca aatccattaa gcaacttaca aacagaatat acaaaacatt tgctagttac
    11701 tattttacat tcggatttac ggactcgttc atctatacta tataatgtat caacaattga
    11761 taaatccaca ttcatattta gatttttagt agcagaatct atatgtcgaa cataattata
    11821 ataaaatcta tcagtaacat atattctatg cgtattaagc aatactccta taaaaaaatc
    11881 aaagacctca cctactttta tatttgtatt aaatctaaca tttttaatta tttctcgcct
    11941 atacaactta ggtgtaattg gaagataatc tacaaacatc aaaatatttt caagattata
    12001 taccccaaca ggaatattag tcaaacaaaa atgtttgatt ccattcacta tattgtaaaa
    12061 attaaaaatc aaaatatcag catgatattt acttgctagc acatacatct cttcgcacca
    12121 agaagcatca ataaaatcat ccggatccaa aaaatacaca tattcaccac gggcaacatc
    12181 aagggcatca ttccttgctt tagatacacc ttcattaggt ttatctataa caacaactct
    12241 atcatcttct cgttcaaatt tctttatata atttaacgta tgatctgtag atccatcatt
    12301 tacaaatatg aattcaacgt catcaaacaa ttgttttttt aagccatcta tacatataga
    12361 aatataattc tccgaattat aacatggaat aacaatacta atttttttca tacaggcata
    12421 aaatgaaagg gttcattctt aattgtagca gcaaataata ttagcaataa tacaacaacc
    12481 ataaaaagaa cagcggcatt aatactctgt cttgatttct tatacaagaa gaatatcaaa
    12541 cacgctataa ctacaagttt aaatcctcta aaataacgaa acggcctagc taaaaccaaa
    12601 ttattaacaa aaacaatctg agccaaagtt ccaaaaaaat acaaatcata tattatatta
    12661 aatttcctcc cataataata gcatttcatt tttttacaat atgatacaat aatcagatcc
    12721 aataaaataa aaacatacat acttacacct gttttcgtaa tatccgcaaa tcgataaagc
    12781 acatcttcag tatacatttc atatccagaa agtgtagcta aatagaatat agtatcattt
    12841 atatttgtca acaaatcaac attatatata gcaacataag acacaacaaa aagcaataaa
    12901 tattgaacat taatactatt aaaatagtga tcttttttca gatatagaaa ataaaatggg
    12961 aataatataa cagcagaata atgaaaacca acagaaatca acacaagagt aaagaatcct
    13021 acaatcctct tatctataac acaagtaata gcacataaga atatacaacc tgcaatatct
    13081 tgtcgaatac cattcatcca atgaataaag aattgaccca taaaaagaga tacaatcaaa
    13141 gcaggataca agaatttaca gtctttcata aaatagaaaa gacaaaacac ttgaatgaaa
    13201 gcacaaaccg caaaaaaaac gattggatgt acacctgcat tactaagcgt atcacgaatt
    13261 aatgcgaaca aaggttcata ttccttatga agaaatggat ttatatatcc atctaaataa
    13321 cctaaatgat cttcaccgac atcgtatcgc atcccaaata caacagcaaa agaaaggagc
    13381 ataaggatta tctcccatct aaaaaacaga tttttatgta tagttacatg ctctctataa
    13441 gatgcaatag aagcacagca aaacataaaa cacattataa atgtataaat aaatactgaa
    13501 agcacgatat caaattataa aagacaggtt atccttaaga atattttcat ttaccgttac
    13561 atccataccg tcaaccattc aacgcctctc gcaaaaaatc aagactcttt tcacgccact
    13621 ccaccagctt accagaatga tatttttcta acaaatcagc aaaacgaaca ccacctcttc
    13681 tctcattcac aacacaacgg aaaggttttt cgaaaataat agagaatact gttccatgaa
    13741 atgaatccgt aattacaaaa ctagcatcac gaaaaatagc gatccattcc tctattgtca
    13801 gcttggcctg tccataagcg gaataacgaa ggataggcaa tcctcttttt ttcgcctctt
    13861 ctgtgattat cagatctact tcctttgcgg aatctagcac ataagcagca agatatctct
    13921 tcttaaaaac aggaactttc atacacaact ccgcatatgt ctcctttcta acaagtaacg
    13981 tgggatcgag tactgccaca gcatctattc ccaaatatct ctcgcaaaga gccactccac
    14041 ttgtctctcg cacagatacg gcatcaaaaa gctgagctaa agaggaacaa acggaggttt
    14101 gtttttctga atattcccaa tagtctacgc caaaagaagc agcataggca accctttttc
    14161 ccgaaaaatt ccccgcaaaa tgcaaaaaca tatccgacaa acgattcaca ttatatatcg
    14221 gacgccacgt ttgatcacta cctaccaaca atgcttctaa accatattct ctaatcatct
    14281 ccatcgaata atttctacaa gtaggagtct tgataatatt tttactcaca aattcctcaa
    14341 atagcggcat ccttctctct ctccatctct taaatcttct cctgcgtgaa ggaataaacc
    14401 aaagaagcaa ggatttgatc gtagaaagaa taaatcttcc aatcgaagga cgaggaagga
    14461 tgtcaatagt aatcggctca tgccccaacc gaatcaagat atgctgcaag gcccaattct
    14521 gtaaaactcc gccataatta cctctaagag gttgtgtcaa tattcctatt ttcatgatcc
    14581 atatttttat cttctttctt attttagtta aaacaggata aacaagttct tctttctcag
    14641 tcttatcagg tcaagtaagt agagggactt tcatactgac tgtctctaga aatgcttgtc
    14701 agatttgaat gtgattaact aatacgtttt acactcttta ggttggttca ctaagatgct
    14761 atacaacttc cgttaggtga actaaacagc tttacattta gccttgggta aactaaatgg
    14821 ctttacaaca tttgctgaca gatgagtaaa gtgtctcatc ttcgtcttgg gcacaaattt
    14881 agcaactaac attcactaaa aacagtgacg aaagaaacca caaagcatca tttgaacgta
    14941 aacatcccaa tggaagaacg aacgtgaaaa gctcaaacca ttttacccct ccgtgttaat
    15001 atctattaat gaataatcct tacaataaac aaagggcaaa gaaatgacag accatgttat
    15061 cagcggtatg ataaacttct taaccttact cctaatatac ttcatctcat ttccattctc
    15121 agggcttttg aagaaaaagc cgctaaaaaa ataaaaagag gacataaaaa aacttagggc
    15181 attaaaatag aattcggatg cggcaccttt tgcatcaaaa aaaccatata ttataaaaat
    15241 atgcaggacg aacatatgca ataagcatac accttttacc gaatcaatag aatagtctct
    15301 caccattgtt cttggatttt aatcatacat aacaacgaat atgaacattc aaaaacacat
    15361 tctttcaatt aatatacttt accggatatc caatagccaa tcagtacgtt caaatcaaga
    15421 cacccccatc tacagggatt atatagccaa caatttgcct tgcttcgcca ctagtgagaa
    15481 agagagcggt tttagctatt tcctcaggca ttgtaaaacg tttactcggc tgtccttgga
    15541 aataagcgtt gtcttcaaag ttcctattat gaggcaacgc tggattggag gtaaggcatg
    15601 tgccaggcgc aataccattc accacgatat cataagcaat aagttttctt gcgattccac
    15661 cagtcaagct atgagcgccc cacttggcca cggcataagg gtcgaaaagt ctttggtagc
    15721 cggcgataga ggtaatgttg agtatattcc ccttgatttt attgtctatc atatacagcc
    15781 cttccatttg gcacatcaaa aacatacttt tcgtattgat atcatatgtc ctgtccagta
    15841 cttccgcagt atatgcattc cacggttcat acttagacat cccacctcct acattgttca
    15901 cgaatatgtc gattctaccc atcatagaaa cggcttcatc gaacttctgc ttataagagt
    15961 caaaatccaa ggcgtcccat accaacgtat aaagcttggc attactttcg gaaagctgga
    16021 agtttgacag tttttcttta cttcttccag tcactataac ctcagcaccc tctgccaagt
    16081 acgccttagc catagctctg cccaatccct cgctaccgcc agaaataaat accttcttat
    16141 tggcatatct ggcatcagga ttggtaaatg taacagagac atattttact cccccgtgtt
    16201 taagggattt caagaaattc acgatgtaag actttattcc cataattact tattatctat
    16261 tttttccatt atgtatttag tgaataatag ggctcctctc ttgttaagat aatagcagtt
    16321 gcgaaacaag gatttgtcat ccgaaaatcc aggctcttcc atacagtcga aataccatgt
    16381 ctcccccccg ttggcttctg taatgaaaga gtctatcagt tgttctttgg cagcagcggg
    16441 aaatttacgg cacaaagatc tatgcatagg tggtatgacc aggaccagcc ttaacttctc
    16501 ctctttgcaa tactcaatca tatcttttaa cattgatata gtcctatcat ataccgttct
    16561 atgactctcc acgaatttat cattcaagtt attgatatta aactgaacag tccatccctt
    16621 tatccaattc tcagcatcac gctccagttg cctatctctc attatcacgt ctttggacga
    16681 aaagactcgt gtccttatgt cacggataaa ttccaccaat gggtatatgg atatagggct
    16741 atttttatag ccctttattt tactattccg gatatagtgt ccaccgggaa tcgttcgata
    16801 gtccaaaaaa ctatagcaac ggtcttctat gtaatccacc gctccactga tcgacgtaaa
    16861 cggacaaagc ggataaaaca caatagcatt atcctttagg aacttgcggt accgcttgag
    16921 tatcaaaaag tcgcctacca tcgtctgcgg cgccacagcc cagttcattc ccttacatct
    16981 catatcgctg taatcgaaat catatacgcc ggaactgctg cctagattca caacgtccaa
    17041 tggctcctct ttcatttccc aaaatttcac gcagtctttg aaaaggacct cgttgtacca
    17101 atgagaagac ttaatgaatg tattgatttt gttctttata taatgtttca tgagatcttc
    17161 tgtattaaca aattctctga tcattgttta gtcttgctca tcttagtctg aatccaactg
    17221 actatttttt ttctttcggc acgtgttatt cctacgtata agataagaat catcaatacg
    17281 acctctgtaa gcaaggatag aataatgaac ctttgccatc catcctccat caaatatacg
    17341 atggccgtag gcacaattac agaacaggca ccaactaaga cacatgggag aacagcgcca
    17401 actaaaagtt cacgtatgtt gaaatgtaca taagaataga caatgaaata agcatcaatc
    17461 ataacagtta tattaatgat gacgagaact atgaacaccg cataggcagg agcacccatt
    17521 ttcaatatgg cataactaat aggcaaggac aatatcatta tggttccatt gagcgaattc
    17581 cccagcttca tcttgccgat agcgtgaaag gccataatca tggacgcacg gaaaacctcg
    17641 gcaagactga gtaaaagtat gatcaaagtg aatacatacg tatcaggagg agtggctttg
    17701 cccagccata agtttaatat gaacctcaac tcaaaacaga tgggcaagat taatgccaac
    17761 atcaagaaga acgaataacg tgcggactta aacgtaagcg agtacatcct ctcataattg
    17821 tgttcggcaa aacttttaat tacctgcggc ctcgtggcca taagaaaatt aatcacaaaa
    17881 tggttgacag ccgtttggat ttgataagcc accgcacgtg ccgcattgac catgggaccg
    17941 aaaaataagt tgagaaggat attaatacct tgcccttggc ttattgatgc caatccgcca
    18001 aacatctccc accctgaata agccagctgc cttttatata aagtcttatc cgtaatccat
    18061 ctgaaacggc actcctgata acgccgatac gtataaaacc tataaaaaaa ctgaatcaaa
    18121 aaagtattca gcattaacaa caaagcataa aacactaagt catccatggg agataaggaa
    18181 aggaggtaag cgatagctaa tcgcgaaaac gcatcatata agcctacata ggcataaata
    18241 gacatatttt catgggctat cagtgaagca ttgtaaggta cttgggtgaa gttaaccatc
    18301 accgtaacaa tagaaaactg atagacccac cacgcagccg atagtcgttc caccggtata
    18361 accattttct cgtaaaagaa ccagaggcct atagtctcag ccaacagcaa gacaataaaa
    18421 gccacagcca tatgcaaatt caatgaaacc gagaaagttc tcttcagcat ctctgcgtcc
    18481 ttcattccca attcgtaagc cagaaaacga ctggttgatg aagacagggc accgttaagc
    18541 actcctatta cggccacaat tccacctacc gcattataaa taccgtaatc ctctacacca
    18601 agcgtttgaa gtatcacacg ggaagtaaat atgcttaccc ccatgacaag taacatacgc
    18661 acatatagaa aaagtgtatt ttttgctata cgcttatttg ttgaagatac ttcctgactc
    18721 atttcagact gcccctttta tttaaatagc attcacacga ttatcattcg ttcaccccgt
    18781 tcttctgcag cagcctcaca atactatcta ggctgtcaaa attttcggga atgatgtcaa
    18841 taccatcaat gacgatatcg tattcggtgt cgagagtatc gaccagcgtc actatatcga
    18901 aggaatcaag cataccttcc tctataaagt ttacaggctc gctgaaatcg aactcggggc
    18961 gtaactcact caaaatcgaa ataattttct ctctcataat ctttttctcc tttaatcttg
    19021 gcaattatat acctttattt atttctaatt aatacataat cataaagtct ctctacttca
    19081 aagccgtaat gacggtaacg tttaatggca ttttcgttac tagctatcac ccaaaagagt
    19141 tgacgcttgg tggcgtggcc agctcgcata aattcattga acaatcggga accaatcttt
    19201 aaatcccggt attcgggcaa gacaaaccaa taacgcagat ataaggtctg cccgttcagt
    19261 tcaaagatga taaaaccgta aacctttcct ttttccttat atacgagcac accctttcgg
    19321 gatatgaagt ccagtatttc ctcgtaacaa ggcagctgtt cagacaaggg gtcaaagttg
    19381 gtatggagca tatcctgtac cacacatgca tcagcctctt cagcgagaca tacattgggg
    19441 acatcgctca ctttatactc caaggctccg aggcgactca tacggtagag ctgttcatac
    19501 acgctgaagc cttgctccac aaacacatct ttcagactcg caatctttcc atcacccact
    19561 atgtcaacga ccagttgctc agacaatata ggtaaaacag ccttcaatcc cccgaccagt
    19621 tgttgcaagg tagtggtaag aaaaaacagg ttgttgaccg aatcggttaa atggagcaga
    19681 aaataaccgt cagggaaaga aacgtaaaac aactctcctt tctctatcca tatggagtgc
    19741 ttcttcctat ccaagaagaa attggacaga tagcccttac gcaaagaacg aatatcgctc
    19801 acaaagccat taatcttatc aagtgaatct atcttatcca ttgacttggt tattatagaa
    19861 caggcggtca atcttaccgt tcgtattacg ctgtaactct ctgatatgat gatacacagt
    19921 gggctgcata taacgaggaa tgctagtaga gataaccttg cggaaagttg ccatgtcaag
    19981 ttcctctgta gcctgataga acatcacaat cttcttgttt gcaaagtcat aaacgacgca
    20041 acagctatcc accatgtgac taccaagaat tgcagtctct atctcgccga gttcgatacg
    20101 ataaccattg tgcttaattt gagaatctac acgacccaca tacataattt ctccatactc
    20161 attctcataa acgacatcac ccgtacaata gattgtctcc ggataataat tatgtagagg
    20221 attctgtata aaggctgaag cagtcttttg gggactgtta taataaccaa gagctagcga
    20281 agaacctcgt acacagagtt ctccttgttc accctttgcc gcccgacgtt tgcgatcaac
    20341 gagaatcaac acgtcactgt tgcgacacgg gaaacctata ggcagaggtt cactatcaga
    20401 aaactctcgt ttcacttcat agaaggtaca gtcaacagta atttccgtag gcccataaag
    20461 gttagcataa cggcagttgg ggaggtgctt acgccagtaa ttaaggtgct tatttggcat
    20521 tacttcaccg gcaaagaaca catccttcat gtatataggc ttttttgttt cgaaaatatt
    20581 gagattggct acattgatga gcacaaaagg aacccaaaac acgaacgtaa ttttctcctc
    20641 attgagatag tcaaccaact tggctgggaa tgcgaaatta ctttctggaa taatattaag
    20701 cgtcgcacca gtggaataca taaggtaaat atcaagtgtt gagttgtcaa aatagaaagg
    20761 ggcttgatta ccaattactg catcactcat aaagtgaaac gtatctttcg cccaatcgat
    20821 atagtcaatt acaccacgat gcgagacaac cacacccttg ggaattcccg ttgaaccact
    20881 ggtaaaaatg ctgtaaacag gatcagtatc aatctgatga gtgaactgtg aaaaagcatt
    20941 ttctatattt atatcaccct caattatatc ttcagccaca agaatccgta catgggtaaa
    21001 atccctaagg gtttcaatat gagaacgatc agttatgagc actttagatt caagagtctt
    21061 gataatactg ctgacacgag aaacgggaga ctttgtatca agaggcacat aaaagtttcc
    21121 actcatatta atacctgcaa aagactcaat catcttgccc cctttcggaa tgtaaacacc
    21181 aattgggtta tttaacccga tattcgtatt cacgagagca gccgaaatct tttgcgcatt
    21241 tctccacaaa tcaccaaatg tgatagacat ttccgaatct ttaacagcta ttttcgcagg
    21301 aaagcgacta acagtagact ggagatattc aataacagat ttttgcatat ctaataaata
    21361 tttttcgatt cttacgagta atggatcggt cactgtttat tcagcggttc atagaaatga
    21421 gttttggaaa gatccagagc aacacttcca cacgtaaggc cagcgccata ggaacaaaaa
    21481 acggcatgcc tcggacggtt tgccttgttc aatccataaa gatcacataa caaattgggg
    21541 atagtggagc tacttgagtt accaaagtcc ttcatgttca ctggaaattt ctcttgactt
    21601 gacttcaatg ccattctaac attcttaata atcaactgac tggattgatg caacgcatat
    21661 atatccacat cagaatcctc ccatttcatc aaatccatca cagtgcggat gctcttaggg
    21721 ccgtttacta tactaaatga gaaaaccccc attccatctt ggtatatata cccaccatgg
    21781 ggcatcatga tccgatcgta tctcgcacca tctgaacaga gatggaaggc catgcctgtt
    21841 gttccttttg aaatcagtga agcagtacct atatcgctcg catcaatact accaacagct
    21901 ttagggtcaa gacaattctt cagcatatca cctccaagaa ctaaaacatt ctgacataat
    21961 ccactatgta tccacatggc tgcttgcatc aaaccataga tataaccggt acaaccataa
    22021 ttaatatcca agcaaacggt ctcattcttc aatcctaatt tatgctggag atagacagaa
    22081 gtatcaggga gcgcccaatc acgagtcaca gtcaatacaa ccaagccgtc tatgctctct
    22141 ctgtcgatgt tatccttact gattagatat tcagcagcgt tgaagcataa atcggatgat
    22201 ttctgattcg catcggttct gtaaacccat tcaactcctg tcgtacggat aacatctctt
    22261 gtttcttttt caccatattg ctcggcgaaa gaagataagg aaatcttatt actcggtagc
    22321 cagcttgcaa tactgcggat agagacatct ggtatgattg ttttcatgcc tttctttctt
    22381 ttacgatatt gaaaagatct tcaattgtat cggcattacg cacgtcttgg gtgtccagct
    22441 ccacaccata ttcttgatag accatcgcta cgacactaag acttgttagc gatgaccaac
    22501 tatccagttc atgaaaatcc aaatcagctt caaaaatagc aggatcttcc tcttcgaatt
    22561 gggaaacaaa tttgccaata aaatctttta attccatata tcaagtattt tttatctaag
    22621 ccttccaaag aatatttttc tccaccacca cggcaggatc acctttcact atactgaaag
    22681 caggtatgtg accggaaacc accgaacgag cagagattat ggcacctggt tcgattaccg
    22741 ccccaggcat caccgtacag ctttccgtta accatacatg ttctttgatg gtgacgggag
    22801 aagaggtttt atatccgcga atagatataa agtgttcccc gttgttatcg cggatagtga
    22861 cattacgtcc acatccggta taccgtccga tagaaatatg gtcagcgcat atgatcgtca
    22921 agccaatatt cgcacctaaa ccacctccta tttccaaagt agcgttcctg aacacctcaa
    22981 tgtcggcacc atacgcaaca ctataaggtt catatttaat ctccatcctc cctccgttct
    23041 caatcaagag cctgctgtcc aggcgagatc ctttgacacg cttacttcca aaatagaagg
    23101 gcgcattcag tatcagctgg gctttggatc ccatgactat agtacagtac ttatttatga
    23161 tgaagaattt tccttccaaa acatttcctt ttacttgtcc gcaaaagaag ttatatcgaa
    23221 agttttttgt ccatgtacca agactccatc ctgaggcttt ttttacgcta aataagaaac
    23281 gggctacgtt cttaagcttt tccttgacgc taaacccctt cttcccaaaa tggggcaggt
    23341 acttcttgat gcaggcatcc agtgattcat tgagggtagc atagaacgca tccctgtcgt
    23401 gactagaatg gcacaaaggc ttcattaaaa ggcgatttcc tgctatggcc ttgtctagag
    23461 ggaagtcctg ctttttcaga gttttaatat tctgtatcaa gtcagcgcct tttttgctat
    23521 gcacaaagac tacggacgtt cccaaatcat tgtcaagctc tttaggtata tactttttat
    23581 cagcccataa atcaccaatg gtaatgtctg tagctctagg gaaacccttg aaggggcatt
    23641 caaaacaact cggccgacat acctcaggaa cgatataatt cagaatacgc cacggattgt
    23701 tctccaacgt ttgatattcg acatctctat tttcaaagag aattttaaaa gtatgcttac
    23761 gccatcccaa ctccttgttt ttagctttaa aatagacaac ctttgaatga tgcttgtttt
    23821 ccagatattc tatgtacttc cggaaaagca atggcgaggc tataccccta cagatataat
    23881 ccaccaaaat caagttgtca taagttttgt gcaggaagcc gcgcagggct gccatctgac
    23941 atggacctcc acaaacaagc acgggcttgc cagtcttcaa ggcttcacga acagcgatat
    24001 aaaatccatc gaaacggctc tgaagatatt tgctagagcg caaacgaggc aagtcggtct
    24061 tatctgctga aaggaactga gacactgacc agtcttcatt atagaccgca ccacccacgt
    24121 agccgccttg cttgtaaacg tattcggcaa gggctgtgaa cgctccacca gaagtgctgt
    24181 cgaaacgtac ctcgatattc ttatgtatgg cggcatagca aacaggaatc tcaaaatcat
    24241 ttttctttag ctcttcagag tgcagattgg ggcagacctt ttcacaaaga ccacaatctg
    24301 tacatttatt tttatcaact tccgggtacc aaaatccctc tatatcggtc ttgaaagtaa
    24361 tagccttatg ggtacataca tcaccacaag cattgcagcc acagcattta cttttatctg
    24421 taatttgaat catttataat ataatttata tcgaacgtaa acagtcattt taaacctgca
    24481 aaaacctaaa atgaaatatt tttaatttta tttcacaata aaggggttat atgtaactat
    24541 tcagcaataa caaagacatg gtacattgtc atcctataac gacaagatgg tattgattgc
    24601 cttaagttgt gattgtttgt tcttccagac agtgtcggcg acaaaatgac gatcctccgt
    24661 cataataaac tttgcatttg cgataacagc ataattcaag aatttattgt cattcggatc
    24721 tgattttatc aaattaaact tataataagg agtaaggaag ctgatatata gattgttcaa
    24781 aataacatct aaggttagtt tagtcatctc ttttcccgtc agttgctcta atatttcttc
    24841 attttcatta aggatctttc agatgcacat aattcatttg cgtcatctaa gaacgactgc
    24901 catattcaat gatatcggtt tctactcaga agactttgaa tcaaactgtt cgtatccaat
    24961 acgattttac tcatcgttca aatctatacg aaagtgtatt gtcctcagct cgtcaagctt
    25021 ctcctgattg agacctctcg aatcccataa ctcatccaaa cgtttgtcca atttttgcga
    25081 gaaatatttc gtcaaaaccg ctttcatctc taatagcttt tcctccgagc catcaaaagc
    25141 aaaaaacttc aacaaatgtt gttgcacggg attaaatact gtcacttcca tattcttttg
    25201 tttattcatc caaaatagat gcttgcatat caaattgatt gtatgaaaat atagtcaatt
    25261 ccttttacca caaacatttc tccttgaaat attccctcct caatccaact cctcaaaccg
    25321 agaattctgg ctcttgaact caggcacgaa tactttcatc tccctcacca tcgggaggat
    25381 ctggacacga agggataatt cgattaatac atggatatgt gttatcacat ccttatagtc
    25441 atactcacga accgccgcca cccgaatttt ctcgtgagga gtctctttcg tattctcctt
    25501 gttgttcaat agctcctcat atagtttctc gccggggcgg agaccagtgt acttgatctc
    25561 gatgtctttg tctacctgta atccggacag ctcgatcata cgcttcgcca aatccgctat
    25621 cttcaccggc tcacccatat cgaaaataaa gatctcacca cccttgccca ttgtaccggc
    25681 ctctaacacc aggcgacaag cctccgggat agtcataaag taacggatga tatcgggatg
    25741 ggtgaccgtc actggacctc cctgagcgat ttgttcccgg aaacggggga taaccgaacc
    25801 gttgctaccc aatacgtttc caaaacgggt cgtaatgaaa cgcgtctcgc ctttcacctc
    25861 tcctcgctcg atcgcaaggc tcaagctctg tacgtagatt tcagccaagc gcttgctaca
    25921 gcccatgatg ttcgtggggt tcaccgcctt atctgtactg atcatcacaa acttctccac
    25981 accataactt acagcggcat ctgccatcac acgggtaccg aacacgtttg ttcgaatcgc
    26041 ctcgcagggg ttctcttcca tcaaggggac atgcttgtag gccgccgcat ggaacaccac
    26101 ttgggggtgc cagttgcgga acacataatc cacacggtcc gggctacgga catcgccgat
    26161 tactgggaca aagtttagtc ccttgtattt ctcttccaat tccagacgga gattatgcat
    26221 cggggtctca gcggagtcga agcaaaccaa cttcttaatc gggaaatgag ccagctggcg
    26281 acagatctcg ctaccgatac tgccggcggc tcccgtgaca agcacggtct tcccttccaa
    26341 cagattgccg atttcgtcca gattaatatg gatctcctca cgacccaaca aatcctcgat
    26401 acggatctct cggacggaac gtttcgcctc acctccacgt agctcctcca tctccgggac
    26461 taccaatgtc ttcaaagagg cctgctcgca ataacggatc aaacggtcac gctcctgatg
    26521 ggcaaccttt atattgggga agagaacgcc atccaaactg ttgcgaggga tcaagcgata
    26581 cagatcctcc acgttctcga tctggtagac cggcaactcc gcaatccgga tgcttttctt
    26641 ggaattacca aaggaaagga agcccatgat gctataattc tgcatgaata cctgacggtt
    26701 agccgatgtg gcgatcatca cgctttcctc ctccgtgcca aagaccagta cccgcttgcg
    26761 tttcttaccg agttgcagga ggacgctgtt atagacattg atcacgaaga cacgcaacgt
    26821 gaccaacatc acgatcgtca acgtactgtc catgattcca cccaaccaat agatagaagg
    26881 gctgaaacgg gctttcaata gccaaagcag caggaacatc aagagcgact tgccgatcgc
    26941 agcaccaccg atccgccaca agccacgcag cgtggaatgg cgaataaccc catgatatgc
    27001 tttgaacaac aagaacgaaa cgatactggc cacaaatgag gagaggccca ctttcagcac
    27061 atccggctct ccaatacgta tatgcagaat ggagaacatt cctagtacgc ccagcaacga
    27121 tacggaaagc gagacgaaaa ggtccgcact aaaaatgatc caacggttga tataccgcaa
    27181 attcaccaga cggcctaagg ccaatcgcca tctgccctta tgaaaatcca tcatttgtat
    27241 tttgtttgtt ttatattcaa tgccctaact tttcccaacg gcggtgcctg tgactcgtgg
    27301 cgtcccgaag cggcgggcgt aatacagctt tccgtccgca agatcgtacc atcaccatgg
    27361 tggatgattt ggatcgcatg ggttgcattg ggcacgatct gcacattgca accgtagata
    27421 tggaagacga aacgtgcttg ttccgcccgc tcatagtttt ctgtcatatc gtaatttttt
    27481 cagtaaggtt atcacttttc gtttcccttg gaaaacgagg tatatatgaa ttgccctgtg
    27541 aagtatatat caattgccta acacagtata tatcctcggg catatgcagt atatcttctc
    27601 aaaaacggcc agttgagcgg tgtctgagac ggctgctcca cgcatcgtta atacgggcac
    27661 agatgttgct gacgctttta cccttcgtga ttcggggggt gatgggtaga aagaggcgga
    27721 tgaaacgctc tttgaccatc tcctcggggg ttattttcgg ctcgttctct tgcatgacca
    27781 gaatgacttg gggcaactcg gtaaccgtcc ggcactcgac gatctgcgca agatagcgtt
    27841 ccagatcctc ttctttattt atataggcac gaaaacggat cgtttcaggc atgagaccgg
    27901 atctaccgtc cccctcttct tgggaggtct ccccgcaata ttcccccaca tagaagttct
    27961 ggatggcttc cgtagcgttg gggagtatct ggttattgcc gccgtgtatg gtaatcgtta
    28021 tatcagacat aaggtatata tgaatcgttt gtcaatgaaa agtaaacagt ttgtcaacgg
    28081 ttatcagcgg atttgatttc gctatccggg ggttgtactt tcgcattgtc aacaataagt
    28141 ttaatctttt taaaaaaaga agtatgatta attattcaac ttacatgtgg aaaagtccac
    28201 tggatgagac cgcaaaggaa caggcgtacg ccaagaacca agtgacgaaa gtgatgagtt
    28261 tcgatgattt cgtgaagcac atctcagatc acaacggtgt tttcacacgc ggcacggtaa
    28321 aaggcgtggt aagcgacacc tgctcatgcc tagtggaaca attgctgaac ggctacaagg
    28381 tacaattcgg cgaactggga atctttagca tctccatcac ctgcgagccg gccgctacac
    28441 tcaaggactt ctccagcgat aatatcaagg cagtgaacat tctattcaat ccgggtatag
    28501 acttcgagaa cctacgttct aaggctgaat tcaacctagt aaccagccgt gcgatccaag
    28561 ccgcctcgct gaaggcggta aaggagaata aagacacggt agacttggct gcgttgaaga
    28621 aaggagactc agaatctccc gatgagatct aaatcctgcc attgagaaat acggctctta
    28681 accatgaagc ttattttatt catttattta aagactacaa gtatgaaaaa aacaaattgg
    28741 aagagcgtct tgctctacat catccgcatt gtcgaactgg tcatcaccgg tgccgccggt
    28801 ggagccacta gcggttggat cggatgagaa ccatcacgct gattatcgtg cattgctctg
    28861 ccaataggca gggcagcact ttacggatga tggacatcga ccgtctgcat cgctctctcg
    28921 gctggaatgg ctgcggatat cacttcgtta tcccgaccga tggtacgatc gagaccggta
    28981 gaccccttga acaagtgggc gctcactgta agaaccacaa tcggtacagt atcggggttt
    29041 gctatatcgg aggactcgcc aacgatggaa agactcccat ggatacccga acggaagccc
    29101 aacgagaagc cctacagggt ttgtttcgtg aattgcatca gcgattcccc aaagccctaa
    29161 tcgtgggaca tcaagacttg gacccgtcga aatcctgtcc ctgttttaat gtcgtgaacg
    29221 agttttccga ttagtttaac gcagggagtc ccttcacctc cctcgtatgc cacgcttggt
    29281 aggcgggagc ggagagttca ggtacagtca ataacttgta atccgccccg ttctgcttag
    29341 ctatatgttt tcgttcatac aaacgaaggg aacgatccgt tacggaaacc atgacaaccg
    29401 gaaaaggata agcgtacagg cgcatcggcg tgatctcact atccggaaag gcacgacgca
    29461 attgataagc ggaacgttcg aacgcgaccc aataagatcc cgtacaatat aaatggatcg
    29521 aggtctgatt cgcacactca cgattcatga tctctctcaa atgccctttc agcaatagca
    29581 tcaaacggat accggaggga gtttcgcttt cctttctcat gacagtctac tatttaatgt
    29641 tttagccaaa tatcgtaatc gtgtaaacgc tgtatcaaca aggccttgct tctcttaggc
    29701 gaagggtcat cccgccaggg atctaccagc tcatgcgcca tacggtaata caggttgcta
    29761 ttcgtgcagc cgtaaagcgt gacgagcagc aaggcacgag aattcactgc cttaaccaat
    29821 ggaagcatat tgcgtagggt ggaatacaag cgttcaaact cctcttcctg atccaacagc
    29881 ttataggccg gaaggagtaa tgagtaaacc ttgcaacgca tcacgtcggt ctccacacga
    29941 agggaagcat agcccttcag cacctcacga accaaaagtt cgtcttcctt tcccaatttg
    30001 cccgagagat aataacgccc caacgccttg tgcatacctt ccgataaacg atcgttatcc
    30061 aaatgggtat aaacatgctt gcctttcgta ttcaactcga tcagttcata ctcgccttgc
    30121 cttacctcaa atagaggaac ccacatacag tcaaggatac gtaccatgac atccttatga
    30181 cctccacccg gttgcaccac cacctcagcc tccatcccca tgaaagaacc cgaggtgata
    30241 cgtacacggt cacctttcag caagcgaccg ctatccggta cgtacaccgg aagctcattg
    30301 gaataagatt cagccatcca gcgtaaggtc tccatctcat gatctgacag gtaaggaaaa
    30361 taagagtgtt cgcccacgga tacccgagga agaagattat ataagggcat gatacgtttc
    30421 aaacggaaaa tctcattctc cgaagcatgg ataaacacat agttgtataa aagaggcttc
    30481 ctcgtattga ccatcttgcc tcccaccttg cgagcctcga catacgaggg ggcaaagtac
    30541 tcgaacaagg gttccccaca acgtttacga cgggaaagct cggcatctaa tccttttgac
    30601 gaatagatat tatcacgtcc cccaacagcg gtaggaagcg tcagtacgta ccagcgtaca
    30661 gcctcctgac tacggcgatt gcgtatatgc accatagctc tatcagagct attacttgtc
    30721 acgatattca ttgaggaaga taattcagag ccttatcaag atattcttgt aataccctga
    30781 taaataaata cttatgtgaa aacaaaaaag gaattactga aaatttgcat cccttcaata
    30841 ctcatgctac ttggcgagta gccttaacaa gaggagtgaa aggatattcc ttagttgtag
    30901 agacggagcg tgtcccgttt catcccctta caatggtatt ttagttacta tcaggcggtg
    30961 ggagacggag cacgctccat ctctacatga tgttatatgg aatttacttc ggataacgtg
    31021 atgatttcgg aaataacgag gccatttcgt ttctattgcc atgtctatac atcagaaata
    31081 agaacgaaga tttaaagaga attaaggttg aaacacaaac aaagcctaat gtttgcttgt
    31141 gttatgttat tttttactac atttgcggca tgaaatgaac gctactcgcc aagtagcagt
    31201 cagtttggct actcgccaag tagcgtactt ttcttcaccc tactttcggc gcataattat
    31261 acacactctc gaaacaaagt ttgtttacgg ttgagagttt ttctaaagag aaactcttca
    31321 agtatatttg cgtagtcttg atagatttat gccctaacag ttcactgatc atctcaatcg
    31381 gtacgttttg ctccttcaag gtcgtggcga aagagtgacg aatcgtgtat gaggtaaccc
    31441 gagtatgaat gccaatggat tccgacagta ttttcaatct gcggttaaaa cctcctaata
    31501 cggtattata ttccttgtag gcatcctcac cggtcttcat tccctctaaa aaaggaaaca
    31561 gatagggcga atcctcggtt gtatcggctg ccaactcatt cagcagccct tgtgcctccg
    31621 ctgggatctc acctgtataa gggatccgct tttctgccga taataagaca agatcccttc
    31681 cttgatatcc tcctttcgca aatgcgccaa atctacgaaa gccatcccgc aaaacaaaaa
    31741 catcaggcaa aaggctgatt gggtcctctt ctgttgcgga tctgtcaccg ggcttgtcat
    31801 cagcaagcgt aagctttccg aaggcaacgc ctttttacgt ttactctcaa cccccgtaaa
    31861 cacatgctta aacaaatgag gaatataggc agcctcaccc acctctaccg ctaaattata
    31921 gatgtgacga atccggcgca tataagtaga taccgtgtta cgagcacatc ccttggccaa
    31981 cagccaagat tgataacgca aaagtgtatc ccgattaata tacgcataag gaatctcttc
    32041 ccggccacaa aaacatttaa acgacctcaa cgcatcttga taactcttcg ccgtggaata
    32101 acgctttttc tcacgcaggc aggtgatata cgtaagtaca cccaccacaa aatcattctc
    32161 attcatactt tatctcctta agaattaata cataaaaaaa tcctctatct ctcgtttaca
    32221 caggaaagat agaggatctt cataaaatcc ttaaagaaat atattatttt ccggctttct
    32281 cagcagcagc tttcttattg atcttcttct tctgcaactc gtaagcgatc ggagtagcga
    32341 cgaacaaagt agagtatgta ccgataatga tacctaataa gatagcgaac gtaaagcttc
    32401 ggatcgtgct accgcccaag atgaagatac acaatacaac caccaacgta gtcaatgatg
    32461 tattaaatgt acgacacaag gtagagttca acgcatcatt gatcacttga taacgatcac
    32521 gcttcggata caaagcgatc gtctcgcgga tacggtcgaa tacaaccacg gtatcattga
    32581 tagagtaacc gataatcgtc aagatagctg cgataaacgt ctggtctacc tccattgaga
    32641 acggaagaac cttccataac aaggtataga aagaaatgat acacaatgta gtcgtagcaa
    32701 cagaggcgaa cgcacccaca gagaatgaca catcacggaa acgaagcagg atataagcgg
    32761 ccatacagat catggcgaag attaccgcta agatagcgct attcttgata tcgtctgcca
    32821 tgctaggacc caccttctgc gaactctgta tgaaagtagt cgtgaactca tctaatgtag
    32881 ttccttccgg aagtaaggat ttcacgccct caaacaattt attctcgatc tcttgatcta
    32941 ccgtaggatc gttatcattg atcttatagt tggtagacac acgtacttga tctgctgtac
    33001 cgatctggat aacactaaca gaaccgtcta actgagcatc cagcatatta cgaacatcgt
    33061 cagtcttcac ctcttgatta aaacgaatca cgtagttacg tccacccgtg aaatcgatac
    33121 cgttattcaa accgatcgtc atcatggaaa tagcacccaa tacgataata gcggccggaa
    33181 tcaaataacc gactttgcga gcacccaaga aattgatctt cggatttgtc agcaagtctt
    33241 tcgtcagaga agtcgtgaat gtcacgttct tcaatttatc tttcgctaac aatgcctcat
    33301 aaacgatacg agtcaagaac acggctgtaa ggaatgaagc gaacaaaccg atgatcatcg
    33361 tcgtagcgaa accacggata ggacccgtac cgaaatagaa caatacgata ccggtaatga
    33421 tagatgtcaa gtttgagtcg aagatagcgg agaacgcatt gctgtaaccg tcagcgatag
    33481 cctttcctaa agacttacca gcacgaagtt cctctttcgt acgctcatag atcaatacgt
    33541 tagcatcgac tgccatacct agcgtcaaca ccataccagc aatacccggc aaggtaagaa
    33601 cggcttggaa agaagcaagg atacccatcg tgaagaaaat gttcaatacc aaagcaccat
    33661 cggcgatcaa tcccggtacc aatccataga atgcgcacat atagatcatc aacagcacca
    33721 atgctaacac gaaagagatc acaccggcat tgatagcctc ttgtcctaat gacggaccaa
    33781 cgacgtcttc ttgaacgata tgtacggaag cagccatctt acccgatttc aatacgttcg
    33841 ctaagtcctt cgcctcttcc ggtgtaaagt gaccggtgat ttgtgaacga cctcccgtga
    33901 tctcatcgtt tacgttcgga gcggaataaa ccatctcatc caaaacgata gcgatctggc
    33961 gaccgatatt ctctttcgtc aaacgagccc aagccttaga gccttcggca ttcataacca
    34021 tgttaaccat ttgctctgaa cgaccggctt gttgcataaa gtcagcgtta gcatctgtta
    34081 ctacgtcacc acctaaagcg ggacttccat cacggttcgt taccttcaag gcatataact
    34141 caaagaactg ctctttatca tcgatcgcct ttacacccca ttttaaagcc aagttacgag
    34201 gcaatacctc tttcacttgt ttcatgttca ggtattcgct gatcttctcc atatcttttg
    34261 cttgagcgat acctaccgtc gaacccggag acaactgacc gttgtactgg ctaatctgca
    34321 ataaagcaaa taatggatgt tgcttagcga actcttccat gctttgatta gcttccgtat
    34381 cttttttatc ttgaccaagc tcagccaaca aagaatcggc ctcacttaca ttcgcatcag
    34441 cggcatcagc gattttctca acattatcgg tagcaacaga atcagcggaa gcctccttac
    34501 ttaagatagt agccaataca ttatcagcgg caaccaattg ttgatagatt tccggcaact
    34561 tataagtttc ccagaattcc aagttagcgc taccttgaag caacttacga acacgttccg
    34621 gttctttcac acccggcaac tcaaccaaga tacgacccgc cgtctccaaa cgttggatgt
    34681 tcggagaaac cacaccgaaa cggtcgatac gagtacgcag tacgttgaat gagttatcaa
    34741 tcgcactttg caactcttgt ttcaaaacag aaacaacctg agcgtctgaa ctctggggcg
    34801 tgattttatc ttttaactcg aatgtactga aaatagcgga aagacgtgcg ccgctatcca
    34861 acttcttata ctcctcagcg aaaaggtcga tgaaatcttt ttggctagtc gcttgatgcg
    34921 cataagctaa atccaacgcc ttgttgaaat tctcgtcttg gttgttgtta gacaacgaac
    34981 ggattacatc cgccacgttc aactcaagga caacgttcat accgcccttt aagtcaagac
    35041 ctaaactaat ttccatttca cggcattgct taagcgtata gcctaaccat accttctgag
    35101 tagatagtga gtctaaataa gcactctctt tcgcaggatc tccacccgca tactcagcgg
    35161 ctttactgtt gtaatgttgc gtcacgaacg agaacgacaa atagaacaaa cagacaagcg
    35221 taagtaacac cgcgaagacc tttacaaatc ctttgttttg catctgaatc ttaggtttat
    35281 gttattacat tatttatatt cgttttttca cagggtgcaa atatagactt tttttctttg
    35341 ataaagagca attagtataa ttatttgtca cgctcatagt ttatttcaaa cgcaaatgta
    35401 tatctttggg gctaaaataa taaggaaaat ataccatgaa acagttatta ttcgctctgt
    35461 tatttatccc cgccctgcta ttcgcacaag aggatcaaca ctatctggca ggggccgttc
    35521 cggttgcaga cggtaaagtc gtttttaccc gagagattaa tgccccctct ttaagcaagg
    35581 cacaaatcta ccaacaacta ttaaaatggg gacaagaaaa ttttaacaca aaggaaagta
    35641 gagtagctta tcaaaatgag gcaaaaggcg agatcgccat tatcggggaa gaatatatag
    35701 tattctccag cacagcctta tccctcgatc gggcgatgat gaaataccgt attatcattg
    35761 aatgcaagga acatgcttgt accctgcaac ttgcgggcat ccgatacgaa tataacgtgt
    35821 cttaccagaa cgagccggag aaatacctag ccgaggaatg gatcacggac gagtatgcct
    35881 tgaataagag caagacgaaa ttgaaccgta tcagcggtaa gttccgtaag gccacgattg
    35941 acttcgcaga caagacgttc gatagcgcag ccaacacatt aggcgcacag ttgctgacaa
    36001 ccgcaccggt agaaccagta tccgctccgc aacgggaaac acgacctgtg gcaccgatgg
    36061 aaggtttcgt agcgttccaa gctgacaaag tacctagcac gatcctccag atgttaccgg
    36121 acaacgcttt acaaatcaaa gcagtaaaag gaaacacgac cgacgcaaac gttgaatgga
    36181 aaggcatagg caatatgttc ggtaaaacga tcagtacaat ctccatatcc aaagatagtc
    36241 ctgcttataa agcgattggc aataacgacg tatatcgatt atccttctcc aagcccggca
    36301 catctgccga tgcgccatgg attattatcg agtgccgtaa acaaggcgag acctccgaag
    36361 gacagcaaac gatgttaatc ggcgagatta cgaatgtatg gatcaaataa cgaaaaagag
    36421 agttgcattt atgaaaaaga ttctattatt aatatatatg atgttccctg tgctagtcat
    36481 ggcgcagggg cataaaggcg atgtagacga atgcgccccc atgaaaaacg ggaaggtatg
    36541 ctatagcgat gatgtagaga tcgagaatac ctctaaacta gaaatattca acgctattaa
    36601 cgcatgggct aagaaatctt atggaaaaga tgtcttctta tccaacgtaa actcgaacaa
    36661 gaacaaaggg accatcttcg taagctctaa ggttgaatta ttgttgaatg atacagacaa
    36721 gactatcatt aaatataaaa tgcgtatcac ctgcttcgac aaccggtaca cgatcgaggc
    36781 aagcgatatc gtatatcaat atgatccgct aaacgataaa aagtacaaga cctataaagc
    36841 ggaagatgtg atcgccaata atggggatag caatacgata gcgctgatca aagatcctaa
    36901 gctattctgt aacgctacct tcttctttgt cgagaacttg ttcgccgacg tatttgacgc
    36961 tgcgcagaac gcagaatccg agtgatgaaa cccttttatt caagtttcag ataacaccat
    37021 aacgggtagt ggtctgaata agcgacctta tccacggaac aattcataga ggtcatgttc
    37081 ggggaatgca ggatattatc gatacggaac cagaagaaat tttgattata ggtaataccc
    37141 attccccggc cagactcggc aaaggcatcc gtcaaatccc cttggatcgt acggtgcgca
    37201 taagaaatag gcgtatcatt aaagtcaccg cataccaaga cataatctcc tttagcgttc
    37261 ttaatctctt ctgataccgc ttccgcttgc ttagcccgaa tccggaaagc aggtcctagc
    37321 ttttgctcga acgctccttt caaatcgtcc aacccatccg agctaaagct ctttataagg
    37381 gatgaataac gggtccgatc ctccatcgtc agtttaaacg attccaaatg gttattaatc
    37441 aaggtcaact tctttccctt gatgttcact tcatgtacgg aagagccgtt ataatccgaa
    37501 tcgtatttca ccatccggga attcgacagc ggatatttgg agaacacagc gatgccgaaa
    37561 ctctggaatt tcgtggagct ttgataaaat acggaacgat aaggatacat gctcaacgca
    37621 tcatagatct tagaggcagt aaggctcttc tctgatttag ccgtggcata ttcctgcaaa
    37681 caaacaatat ccgcgtccga gttagcgata tattggataa tcttgttcgg agctatcttc
    37741 gtatgattct tgtacccaaa agccatcaca ttataagtca gcacctttag tacctcttcc
    37801 cgaggaacat ccttatgcga gtgaaacgga aaatagcgtt tcacgggacc ccaacataac
    37861 aagaaggaga atatgccgat caataagaac ttccattccc ataagaacag ccaatagata
    37921 ataaagcaaa gattgactac acataagact ggaaaggcta atcccagata agataacgtc
    37981 atactcgtct caggagacac ccgatccgaa taagccgaga ctatcaacaa tacgacagcc
    38041 accacattcg ctacgacgaa taagaattga agaaaaatcc gtagagtttt cataagtatc
    38101 tgttatttct tactggcgtc gaaaagtcgc tttttctctt cagcggaaag gctctcataa
    38161 ccggaacgtt tcaatttatc cagtatagta tctagatcca ccgactcctg atgtttacgt
    38221 gcgttatact cataatccgt ctcgttacgt ttataagtca cacgcatctt cggtttccgt
    38281 ttgcccaaat tcacgaacca gtcgatcaac cgattcatcg gagcggtcaa gtcctttcca
    38341 ttacgaatac gggaagcgaa ccacatacca aacaaagccc cgccgatatg ggcgatatgt
    38401 cctcccgcat tatcagaagt catcgccaac aaatcgatca ccagcgtaaa gatagccaaa
    38461 taaattaatt tgatccttcc gatcaagaat aaattaatct ccaaatcctt ccggtaaaac
    38521 gacacggcga aaacgatcgc cataacagat gccgaagccc ccatcaaata gctaaaagag
    38581 gccacgttct ggaaataagg gaaaatatta taagcaagga caaacaatac cgcacccgca
    38641 agacctccca atatatacaa gcctcccaac tgccgctcac tgaagaaatt caagaacaat
    38701 cccccgaacc aatacaacca aagcatattg aacaagatat gcaagaagtc aaaatgagtg
    38761 aacatataag taaataacgt ccacggacgg aagagcaaaa gttccggaga agccggtaac
    38821 tgcaaatact gcaagaaagg taccccttgc acattaaaga gcataaacaa tacgctggcc
    38881 aaacgtatca agataaacaa gcctacattt atatatatca gtttcgacag gatattacct
    38941 gactgaaaca tacgcttcaa attagtaaaa ataccgtcca ttgtctgcat ctttcttttt
    39001 ccaataacga attaggaaat aaccgaataa catacccccc aaatgagcga aatgcgctac
    39061 cgtatcgcca ccaaaactag ccacacccat aaatagttcg gcaagaccat aaaatattac
    39121 gaaatatttg gctttaatcg gaatcggtat gaacatcaag tataaaggaa cattcgggaa
    39181 gatcatggcg aatgctaaca agattccgaa tacggcaccc gaagcgccaa tagtcacgaa
    39241 ataattcaag aactcactct tgctgataat ctgggctcca ttcaagttta tcatgtcttg
    39301 gctagcgaag atcacatccc gcaaattaaa gaaccatacc acctcttgta ccaaaccggc
    39361 gcctataccc gtcacgaagt aaaaaatcaa gaaacgtttt gggccccata cgttctccaa
    39421 tacccggccg aacatataaa cggcgaacat attaaaaaac acatgcgcga acgaatgggt
    39481 atcgtgcatg aacatataag aaacgatctg ataagccttg aagtcggtag cacccgggaa
    39541 gtgaagccct aataaatcca ctaaatcgat gccgactttc ggcagtgcaa ggctggctac
    39601 ccaaaatagc aagtttataa tgataagatt tttcgttacc ggcgggatac tattcaagaa
    39661 ccccgaattt gtctgattca tcatatacta cgttaattta gcggcaaagg taaatatatt
    39721 ttagccgttt ttgcccataa taatactaaa acatatgtaa atcggtaaaa aaagtaggtt
    39781 tttcttttgt gatatttcaa aataaaacta catttggagc cgtctatcgg ttatcatagt
    39841 tttgtttaat atattaacag tcaaaccatc atgaacaaat cagaatttat tagtgcagtc
    39901 gctgaaaaat caggtctcag caaagtggat gctaaaaagg cagtagaagc ttttgttgac
    39961 acagtttcta acgaattaaa agaaggcggt aaagtcgctc tacttggctt cggttcattc
    40021 tctgtgtcag agaaggccgc tcgtaaaggt gttaacccga aaactaaaga aaccattgaa
    40081 atcgcagctc gcaaggccgt gaagttcaag gctggtgctg aattgaacga gctaatcaaa
    40141 taagaaacac cattattctc tatagaagaa ggatacgatg caaattgtat cctttttttg
    40201 tgtacctttg cgtacaaaat aaaatccgaa ttatagttag acgaatatgg ttatcgaaca
    40261 acagattacc ggggctatca tagccggcat caaagagctg tacggagcgg atgtcaccgc
    40321 tagccaagtg cagttacaaa aaacgaaaaa agaattcaag gggcacttga ccctagtcgt
    40381 attcccattc cttcgcatgt cgaagaaatc tccggagcag accgctcagg aaatcggtga
    40441 gtacttgttg agaaacgagc cagcggtagc tgaatttaat gtaatcaaag gattccttaa
    40501 cctgacggtc gcttgctctt gctggatcga tttactgaac tcgatcaatg agcagcccgc
    40561 ttacggtatc attccggtta ccgagcagtc gcctttggtt atgatcgaat attcttctcc
    40621 caatacaaat aaaccgcttc acttgggcca tgtccgcaat aacttattag gatacagctt
    40681 atcgaagatc atgaaagcga acggtaacca gatcgtaaag acgaatatcg taaacgatcg
    40741 tggtatccat atctgtaaat ccatgttggc ttggcagaaa tggggaaatg gagctacccc
    40801 agagtctacc ggaaagaagg gcgaccatct gatcggtgac ttttacgtat tattcagcaa
    40861 caaattaaaa gaggagaccc atgcgttaga agcgaaaggc cttaccaagg aagaagccga
    40921 ggctcaatcc accttgatgg cggaagcccg tgagatgctt cgtaaatggg aagccggaga
    40981 caaagaggtg cgtgcgcttt gggaaatgat gaataattgg gtatacgccg ggttcaacga
    41041 gacttataag atgatgggcg tagatttcga taagatttat tacgagtctc aaacgtatct
    41101 ggaaggaaaa ggtaaggtga tggaaggcct agagaaaggg attttctatc gccgtgaaga
    41161 cggctccgta tgggctgatt tgacgaaaga cgggctggat gagaaattat tgcttcgtgc
    41221 ggatggaact tccgtctata tgacgcagga tatcggtacc gccaagctgc gcttcgatga
    41281 ttacccgatc aataagatga tctatgtggt agggaacgag cagaattatc acttccaagt
    41341 attatcgatc ttattggata agttaggctt cgagttcggc aaaggattgg tccacttctc
    41401 ctacggaatg gtagagctac cggaaggtaa gatgaagagc cgtgagggaa cggtcgtaga
    41461 tgccgatgat ttgatggccg agatgatcag taccgcacgt gagatttccc aagaattagg
    41521 gaaattgaac gagatgactc cggaagaggc tgagaatatc gcccgaatcg taggtcttgg
    41581 ctccttgaaa tatttcatat taaaggtaga ccctcgcaag aatatgacgt tcaacccgaa
    41641 agagtctatc gacttcaatg ggaatacggg accattcatc caatatacct acgcccgtat
    41701 ccgttccgta ttgcgcaaag cagcggaaca gggcatcaca ttaccggagc agttaccgct
    41761 tactttcgcc atttccgaga aagaagagaa cctgatccaa atgatcgccg attatgcaga
    41821 gatcgtgaaa gaggcaggta agctatacag cccggcctgt gtcgccaact atatttatga
    41881 tctggtaaag gaatacaatc aattctatca cgatttcccc atccttcgcg aagagaatcc
    41941 ggaattgaag aacttccgtt tagtcttatc cgccaatgta gctaagatcg tgaaatccgg
    42001 tatggattta ttaggcatcg aggttccgga aagaatgtaa cgatagaaga tgaacataaa
    42061 cgagaaaaca agaaaggctc tccttcgatt tcaacaaaat gaaatcacgg agagccttct
    42121 ctatgcgcaa ctcgccgcta tcgagaaaga tccaagcaac aaggaagtat tactacagat
    42181 agcgaatgac gagaaaggac attatacgat cctgaaaaag tatacggggc aagagatctc
    42241 cccgaataaa ttacgcatca ccaaatacta ctggttggca cgtatcttgg ggattacttt
    42301 cgccattaag ctaatggaag gtagcgagga aagcgccaag aatgattacg cctcttatga
    42361 tgagtatccg gatttgcaac aaatcgcacg tgacgaagat gagcatgagc agaggttgat
    42421 cgccttgatc aatgaggagc ggttggaata tatgggttct gtcgtactgg ggctaaatga
    42481 cgctttggta gaatttacag gtgctttagc aggctttacc cttgccttga gcgactctag
    42541 attaatagcg ttgaccggaa gcatcactgg aatagccgcc gcattatcca tggcttcctc
    42601 cgaatatcta tctaccaagt ccgagaatgg aaatgaaaac gggaaacatc ccgtcaaggc
    42661 atcgatctat acgggaatag cttatatctt tacggtagtc gccttggtcg ctccatttat
    42721 ctttatatca aacgtattaa tggctttagg gcttatgctc atcatagcgt taagtatcat
    42781 cgcccttttc aactattatt attccatagc gagaagcgag agtttccgga agcgttttac
    42841 cgagatggca gtacttagtt ttagcgtggc cgcattaagc ttcttgatcg gatatgcgtt
    42901 aaaagaattt acgggcatcg atgtctaaaa aaatcatagt tatgttttga aaaattcata
    42961 gttatgagtt tagtaaatca taactatgaa tttttagagc tataatcaag cctttttccg
    43021 tgtcgtacgt ttcttcgtcg cggcaggttt ttctcccgcc tcggcgatta tcttctggca
    43081 ttcctccaag gtcaagttct ccggtttctc tatcgtctta ggaattctgt aattcttttt
    43141 cttataagag atataagggc cgaagcgacc attcaagatc tccatttccg gatcctcatc
    43201 gaacttcttg ataaatcgtt gctcatcttt ttgttttttt gcctcgatca actcgatagc
    43261 ttcctcggct gttatcgaca aaggattcaa gcccttcggt atggatacga actttccgtc
    43321 atgacggata aacgggccaa aacgtccgac agcggcaacc atgaccttac cttcatattc
    43381 accgatcgta cggggtagat caaacaattt caaggcttct tccaaagtaa tcgtctcgat
    43441 agactgcccc ttcatcaagg ttgcgaactg aggtttagga gcctctttat cctctgggtg
    43501 cgcctgcccg atctgtacga ctgggccata acgaccgatc ttcacgaaaa caggtttgcc
    43561 gctcttcgga tcgataccca attcacgctc acccacttta tgctccgtac ggacagaggc
    43621 tgcctcttcc acgatcggat ggaatagttt atagaattta tcgatagcgt ccgtccatac
    43681 catctcgcct tccgctacgg catcgaattc cttctccacg ctcgccgtga agttataatc
    43741 cataacgccc gggaaatact ccatcaagaa atcattcacg accgtaccga tatcggttgg
    43801 catcaactta ttccggtcca ctcctacgat ctccgtcttt tggacttcct tgatcgtatg
    43861 ctgagccaag gttatgatat tataagtacg ctccgttcct tccttatccc ctttcacgac
    43921 atactctcga ttctggatcg tctggatcgt aggagcatag gtagaaggac gaccgattcc
    43981 caattcctcc aaacggcgaa ccaaacttgc ttccgtatag cggggaggac gttgcgtgaa
    44041 acgttcggta gcgacgatat ccttcatact caatacctcg ttcaaggtaa ccggaggaag
    44101 aaggccgttt tcctgttcct tctcattctc gtcatcaaaa ctctcgcggt acacctgaag
    44161 gaaaccgtca aaagtaatga cctcaccggt agccacgaac ttctctttct tgccgccgat
    44221 gcctacggag atcgtcgtac gctccaactc ggcgtccgcc atctggcaag cgatcgtacg
    44281 tttgcggatc aattcgtata atctcttttc ctgagcggtc ccgcttatct catcattgct
    44341 gatataggtc ggacgaatcg cctcgtgcgc ttcttgcgct cccttgctct tggtatgata
    44401 ttgacggaat ttataatatt tctcaccgta ggtatccaag atagcctctt ttgccgtccc
    44461 caaagccaaa tcacttaagt tcacggagtc agtacgcata tacgtgatca atccggactc
    44521 atacaggcgt tgggcgatca tcatggtctg cgagaccgaa taacccaact tacgggcggc
    44581 ctcctgctgc aaggtagatg tcgtaaaagg aggggctggt gttttacgca ccggcttttt
    44641 cgagatatca tcgatcgtga aagaagcgtc cttgcaagat tcaaggaatg cctccacctc
    44701 ttccttatct ttcaaacgac ggttcagctc cgccttgagg attgtcgtac catccggcaa
    44761 gataaagcta gcgatcacac ggtaggcggc ctccgagaca aactcgttga tctctcgctc
    44821 ccgctctacg atcagacgta cggcaaccga ttgcacgcgc cccgcagata aagccggctt
    44881 caccttacgc caaagaatgg gggatagctc gaaacccacg atacggtcta agatacgacg
    44941 ggcttgctgc gcgttcacca aatcgatatt gatatctctc ggcgtctcaa tcgcatgtaa
    45001 tatagcgttc ttggtaattt catgaaaaac gatacgtttc gtattctcag gtttcaatcc
    45061 taatacctca tataaatgcc aagagatggc ctctccctcc cggtcctcat cggaagccaa
    45121 ccaaacctgc tcggctttct tcgcttcgtt cttcaattcg gtcacgagtt tcttcttatc
    45181 tgagggaatc acgtattccg gggcataatt gtgttcgagg tctatactga aatctttcgt
    45241 tttcaagtcg cggatatgac catagctaga cataacctta tagtcctttc cgaggaactt
    45301 ctcgatggtt tttgccttgg cgggtgactc cactattacc aaattctttt gcatatctat
    45361 tttttgctgg ttagaaatcg ggtgcaaact tacacaaata attaacgtac gcagtatatc
    45421 gatcactaaa aaagcgtttt ttcctataca ttatatatat agtcatgcgt ttctatttac
    45481 ctttgcggga caaaatcaaa aagctattca aaaatatgga agagataaag cgacttattt
    45541 cagagaataa actagaagaa gcgatccggc tcttggacgc ttacctcacg gagcaaccga
    45601 gatccgacga ggcttggttt ctcctcggaa aagctcatta taaactaggc aacgtacgcc
    45661 tagccctcaa cagctacctg caagcgatag agatcaatca ggaaagcccg gcacaagcgg
    45721 cctacgatat ggcgatcaag gtgctggatt tttataataa ggatatgtac aaccattaag
    45781 aagatgatga acggcccccg ccgccggagt cggaacggta tcgaagcaca tggcgaccct
    45841 agccgcataa ccccaaagct aagcgaaacg cacggcgacc cccgccgcac gactccaaag
    45901 caaagcgaaa cgtatggcgc ccctcgcccc ccacttcgct accgttccga ctccggcggc
    45961 gactattatt taccaaataa gcatagtatc caaattaatt cctaccttta gccactgagg
    46021 acaaacaata agttaaacct taaataaaaa aaaatgggaa catacacgaa aatcaaaccc
    46081 gcgggcctga ctaaattgaa caacgcagag tacacaaact tcatgaacgc cttctaccgg
    46141 ctggcgttcg ctgccggagg gggaggtggt gactccgaaa gccccgacga gatcagtctg
    46201 gacaataacc cgctaggcat caccgacgcg caaaaggcgg ccttcgagaa ggagctgccc
    46261 ctaatgaccg acctcgtgaa ccaatcccac atcagcgacg agaccgccca gttgctagac
    46321 ttggacaaac aacgcgacga cctcgtggtc tatctcacca cctcggtgtc gcaaatgagg
    46381 aaaagcccca tcgaggcgca acgcacggcg gcacagactg tctacaatat tatcaaaccc
    46441 tatatcggca tctataaatc ggccaaccag caagagacgg cgcagataca gggtcttttg
    46501 ctagatctcg acaaggaggg ggttccggcg ctgatacaga cattggggct gaaagagata
    46561 ctagatagcc tccgtgcggc gaacgacgaa tacgcgaaac tgaccgccca gcgcaccggc
    46621 aacagggcag cctccatcaa agaggcgagc gcagtcgtac gcctacgtat ggacgacctt
    46681 tacgatgata tgaccacgat cgccttcgtg cagagcgtag cggctcccac cgccgagacc
    46741 gcccgcttcg tcaacgagct gaacgccctt atcgacgaga ccaccgccct ctacaaccag
    46801 cgcgtcggcg cagcgaaggc ggcagccaag aggaaagaat aaactccatt tatgtaaaag
    46861 gctataagat taatctttta aattaaatca tcatgaaaaa aacattatta accttcacat
    46921 tattagcagg cttatcttca tgtactaact tatcggaaga tttggacatg atcggtacgc
    46981 aaaatattac tcaaacaaaa tccgggaatt tatccataag cgaaaatgaa cctgcaattg
    47041 tcaaagattt aagaaattat atttcccaaa ttaaacttca aggaaagcag gcccgtgtcc
    47101 tgacaagtta tacattgact ccttacatat acaaagagga tactatcatg tatattgcta
    47161 attacgagga tggttgggag acacatcaat taggaatcaa ctggggatac gatggctcgt
    47221 atgattattt atggctcgag gctagctcct atagcgattg ggtatcaaat accacttatg
    47281 acacagaacg ttatatgtta aaataatcct tttaattatg aatacatcac tatttaaata
    47341 cctcatgcta tctatgttct ccttggtctt tttctgtaca tgcgataaag acgatgaact
    47401 gagtggagaa gaatttcgag taacaatgga aaaccgattc ttctcaataa agacatccaa
    47461 gacatttaca aagaaagatg gctcgacaga aataatgcaa gaagggaaat cctatcttgc
    47521 tgattcgccc tcaactattt ggttccatga cagtaagcta tatattccaa tacagataag
    47581 tagcaaagac actctatggc agaaatggaa cgcttatcaa cgagagaaag gactagggaa
    47641 catactatta cttgtcggac ataaatacat gtatgaatct caaggaaatg gattaatcac
    47701 ccccgatcag ctattggtac atgagcagct aggtggtcgt ttttatttaa aaacggatgg
    47761 agacaatcta ttacacgcaa cgatccttta tccggatgat atcgctgacg atgatacaat
    47821 cttcccaaaa agtgagttct attatcaaga agagctatca cctgataaaa acgtcagctt
    47881 agaatatcat gtttacgact cagacgagga agcaatagcc tatatcatag aacaaatgaa
    47941 ggactggaag ccttccgaat gatgctaatc agcctctcat ccgatgatca gaacaaaaag
    48001 agccgtgtca ttactcaaga atagagtttg acacggctct cttttaaatt tagtagttac
    48061 aatcagtaac atttccgaat agtcacttct aaatccgtca caccctcgtt ctcataaaat
    48121 ctgcccttta taagtcagcg ccaacatcgt aatatcatcg ctctgcgtag cgccgttcac
    48181 gaatgattgg acggattcgg atataccttc gatcatggct ttgggagatt ggttcttcac
    48241 ggagctacaa gcctctacca aacggatatc tccatattgc tcgttccgca ggttcatcgc
    48301 ctcactgatt ccatccgtat agaggaacaa gctgtctccc gcttccagtt tcaaggattg
    48361 ttctttataa gctaatcccg gcacgactcc caaggccatc ccaccagtca tcggcaaaag
    48421 agatacctta tcgttcttac gaatccaaac cggacgatta tgccccccat tgcaataaac
    48481 cacgtcgccc gtatggatat tcaagatcgc gtaaaaagta gtaacaaaca tcccattgac
    48541 actctcacgg cacaatagat cattcgattc cttcatgcag accgccgggg aaagctgcct
    48601 aagcgccgta gcacggatca ccgtacggct gatcgccatg aaaatagcgg cgggaatccc
    48661 cttatccgac acgtcagcga tcgtaaaacc cagatgatta tcgtccacca agaagaaatc
    48721 atagaaatca ccccccacgg ccttcgccgc gctcatggtc gcatagagat cgaattgctt
    48781 atattgcggg aacggaggga actgcttcgg caagatcgat tgctgtatct cacgtgccac
    48841 gttcaagtca tattggatct cctctagctg atgatgttcc ttttgggcct ccttgataaa
    48901 agaaatctgc tcgaccgcct tctcgatcgt acgttccaga tcctccatat cgatcggctt
    48961 ggtagcgaag tcgaaagcac catggttcat ggcggtacga atattctcca tatccccgta
    49021 agccgatacg atgatacatt tcaaggccgg gttacgcatc tcgttaatct tcgtcagcaa
    49081 tgtcaagcca tccatctccg gcatattgat atcgctcaat atgatatcaa agtccggatg
    49141 gtccaacatc atcctcaacg cctccaagcc attatgggca aaggagaact catactctcc
    49201 cttacggatc ttccgacgga aatattgggt tagcaacgct tccagatcct gttcgtcgtc
    49261 tacgcttaat atcttgatcg ccataattct tctgtttatt tcgttaatgg aataaggaat
    49321 atgaaacggg taaactcacc ttctttcgat tccacctcta tcttcccgtc atgcttctcc
    49381 tctataatgg atcgagtgat agatagcccc aagccagttc cctctcccac cggtttcgtg
    49441 gtgaaaaacg cggagaatat ctgctcccgg atatcctccg gcataccgat accattatcc
    49501 tcgatactta atcttaaaga atctccctcc ttccgtagat ccacggatat aaccggctca
    49561 tacccgatcg gcgagagctt ggatttacta tagaccgcat agcaagcgtt attcatgaca
    49621 ttcaataccg cacggctcaa atcctgtggg atcactttca gcatcggaag cccttcctcg
    49681 taatgctccc ggatcgcgat attgaaacct ttatagttcg ctcgcatcga atgataagcc
    49741 aaccaaacat attccttcac cagattcttg atatccgtag ggatgtactc gtcatccttc
    49801 cctctggaat aaagcaagat accccggatg atacttgtcg cccggtttcc atgttcctcg
    49861 atcttcttca agttaccatg caaatcgtta acgatctcgc taaactcctc atgcaaggcg
    49921 gtcagcttct cccaagattc cggaggcaag acatctttct cttcttctaa tatatcttcc
    49981 aagtcatcca ctaacttaga ggacagctta ctgaaattga tgacaaagtt gagcggattc
    50041 tggatctcat gtgcgatccc ggcactcaac atacctaaag aagataattt ctctaagttc
    50101 ttcacttgca aacgtagccg ttctatttcc ttactctggt cttccatatc tattcctcct
    50161 ctttaggcgg tgtaattgtt ttcggttgat atacagggat cgtaattaga aactgggtat
    50221 attctccttt cttactctcc acctcgatgg ttccccgatg gttttgcacg atctcacggc
    50281 ataggtaaag ccctacgccg gccgcttccc ccgttgtctt tgtcgtgaag aaaggagcga
    50341 atatcttatc ttttatattc tcgtcgatac cggacccgtt atcccggatc gttatttcca
    50401 gcatatcctt attgaccttc aatccaagga atatctccgg actaaaagtc acggtctccg
    50461 atttcttcaa cagggcatac atggaatttt tcaatatccc ggccagaacc ttactgaact
    50521 gctccacgtt tacctccatc atcaaagaca gcgtcaaatt atcgaaaaca atccggatat
    50581 tcttctcttg aatatcctgc tcatacgttt tcttcaattt atccaaggcg atccggcata
    50641 atccgtttat gttggtaagc gtaagattac ctcttcggtc tttcagcaat tcctccatcg
    50701 ccttaacgat acggaccgta ttgaaaccat gctcggagat cttctccaaa ttactggtca
    50761 tcatattcaa caaatcaacc gagtcgtcat acacatccgg tttcagatgc tctttctgac
    50821 tatccagatt ttcccggaga tccttggcca gccccgatgt cagatttgcg aagttattga
    50881 tataattcag tgggttcaag atacggtcca ccaaaccttg agtcaattgt cctacggtag
    50941 ccatccgttc cttacggacc agctcgtcct gcgcctcacc caaggctttc aaagcggccg
    51001 ccaatttctc ggattcctct tggatcgcgt ctttctccga acggatctcc tgcgtacgct
    51061 cctctacctc ttttaccaaa tactcttttt gtttgagttt ccgcttgaaa accaacttag
    51121 agatctggca aaacagaatc aagaaaagca atccgatcca ttcttgatga ccgaacttca
    51181 cagatacaca aataccgacc aagctaccca gcgtaacccg ctcgcaaagt ttaatccgcc
    51241 tttttaaccg atcgatctcg gtatgtaaat cctgtatcat gatgaacctc ctttcctaac
    51301 tataaatagg caacgtaatc gtaacttccg tatatttatc tttctccgac tcgatagcga
    51361 tcgtaccctt atggttcaac acgacctccc gactcaagta aagacctgtt cctgccgctt
    51421 ccgcggtcgg tttggtggta aagaacggag aaaagacttt cgtctttatc gtttcttcta
    51481 taccgacgcc attatcacgg ataaccactt gcaacttatc cgcttgaata cgcaatacca
    51541 acgagacaga aggctgatat cccggttccc cgagcttttt caagaccgca tatatactat
    51601 tatccaatat ctgcaacaag gcttttccca tctgatcgat attcacctcg attgtcaacg
    51661 gtacggaaag cccggagaat gatagatcta cttgattctt ctcgatctcc ttcgcataat
    51721 tctttcgcaa gatatccaga ttgaccttac ataaatcatt aatatccacg caggttcgat
    51781 tcgccgaatg atctttcagc aattcttcca tcgcttttac gatccgcacc gtgttatcac
    51841 catgcttggc tatcttatcc agattgccag tcaaaagaac cagcagttct tgcgtatcat
    51901 tataattatc gtgtttaccg gtctcttcgt cctcatcgat attctgcttg atatctttcg
    51961 ctaatgcagc agacaaatga gcgaagttat tgatataatt caagggattc aagatacggt
    52021 ctaccagacc tttcgttaat tggccgatcg atgccagacg ttccttacga accaactcgt
    52081 cttgagcgtc cgccaaggca gaaagggcac gggatagttt ctccgactcc gcttgcatcg
    52141 catcccgctg gaaacgcaat tccatcgtcc gctgttcaac gagattagag acgaactgtc
    52201 tttttcgcag acggaattgc gtataatact ttaacaggaa tagaaggact acggctccca
    52261 ccaaataata aaccagttct tccttcttct ggtaaaccgc caaggcgatc cacgccgtcc
    52321 cgatcacggt cagcgtctcg atcacccgca tcctccagcg aaggctttcc agttgtttga
    52381 tatttatgtc gcccatcctt cctgtcctcc ggatatcaga aattgatatt cacgcccaac
    52441 atcgcattaa aactctgcat cggataaccg taatacagtt cgtacttctg gcaaagaata
    52501 ttggtcaact tggcataaac accaaaggta tcgttgaagg tataggtacc tgttaggttt
    52561 agctcgttga tgttatccat cttaaactca ttcattttat cgtacgtcat accagtgttc
    52621 ccattgacac cccaagtccg tacattcgca taacgtccgg tagccaaata ataatccaaa
    52681 gcgatagata atttctcaat cgggcggacg gtcaggttcg cattcagttc catttccggc
    52741 ttcccccacg catgaggcaa ctcgccttca tccgtttccg ctttccaatt attatataca
    52801 cctttcaaag caatatcgaa ccattgttga taactatact tcaagttggc tcccacgaaa
    52861 agttgcttcg tgtcgatacc cggctccgca acactgaaac tgccgaaata attcgctgac
    52921 caaacatcag actgagtaaa cagcacatca tcgctcgtta tcttatatcc ggcgaacaca
    52981 tcaaaccaaa agcccggtac cacgccgctc cggataccca agacagcgtc cagccaattg
    53041 cgcgagggca atagttctgc catcgggtag aggtagcggt tcacacgcga catctcgtac
    53101 atgctgttgg agtacatctt gccgccagcg ttcacgtata gctccgtctt gtcggccacc
    53161 tccacatcgg cggctacatt cggagaggcc atgaattttg tctcgtcgcc cgtagccagc
    53221 atcacgttcg cacccagctt taaattccaa ttatcaccct ctaccttata ataaggcgac
    53281 aacatcgcct cgacatggtt cttgaactca tattcataac ctcctacctc cggcaaactg
    53341 taattgaaat attcgaccaa accgcccaag cctactcgca tattcccatt gaaaccagcg
    53401 ttcagatcaa actttgcctc tagagtatgc tccgtagggc cgtccatcac cctacttaat
    53461 ccatatttat gcgagaaatt agtataacct aagtccaaca aatagccaac ctcagcctcc
    53521 tccttcgact cgaaacctat cgtagcagcg atcgtctggt tcacttggtt ggtttcgcga
    53581 tctctctgta acaaatcctc cgaaggggca taactggatg taggatcaga caatgccgcc
    53641 ccataataat tgaatgcgga gtagccgtac ttcgctccga tactgaatat cgtcttctcg
    53701 aaagcgtgct tgtagttgat gcctcccaag ttgtcattga ttttcgcctt gacatcataa
    53761 tcctttggct ttccgttcgt ggagcgatgc gaataccata gattcagctg atccttctca
    53821 gtactcagga tatgatagcc caagtctccg ttgatattca tgcgcgtacc cataccaaag
    53881 ttaaaatatc cccgacgctt gttgtaatcc atctgcgtca tgatatttcc ggaaggcaac
    53941 aaactaatct ctttctgcgg atcggcggcg atcgtataat tcgagtaatc gatcgggatc
    54001 ttacgaacct ccggctcttt caccacggga agcgtattta ccttgctagc gtcctgcacg
    54061 gaaggatcat actcccgttc aagcgtcatc tctcggttca ggttcttttc tttcgtaaca
    54121 tcctcttgcg cactcgcagc agcagccgaa cccagcaaag ctaccacaca caacgccttt
    54181 acattatata tagtcttcat cgctttcttt tatttcttta gtttacccaa tctgtcttcg
    54241 atcatcgcgg cgatctcatc atcgcccttg tagttgtttt gcaaactggt cagatattga
    54301 cgagcttgga aatcatcacc ttggcggata taaatatcag ccaacaagat aaagccccgt
    54361 gccaaccaat attggtgagg cgtaccgttc tcgatgaagt tcatcaagac agtctcggca
    54421 ttcttatcat ccttattatc ataatacaat tgagccaata gatatttagc ctccgccccg
    54481 tgtatcgtac gggtatcctt gctgatctcc ttcaagtcgg ccaacgcctt gttctcctgc
    54541 ttcaagctga tataagcctt cgcacggaca taacgggcct cggacataat ctcgggagat
    54601 agcttcggtt ccttcagcaa atcgttggcg gcaagcaaag cctcttgcgg ctgaccggtc
    54661 aactcggcgc aacgcatcaa gcccaattta gcggcctcct tattctccgg attctccgct
    54721 accgcctgta gatgcttgaa actttccata gcggcggcgt aatccttatc cagatactcg
    54781 atctcagcct tacgagccca agactcttcc ctgaatttcg tatcaccgct ctccaatacc
    54841 aacgagaaca gacgtttcgc ctcctccaga tctttcttgg caaaagcgat acttgccaaa
    54901 tagaaattag cgttcgagct aaacgctccc tgcgggaagg tttgcaaata attcgtcaag
    54961 ctacgacgag cgccctcatt atcgcctcgc ataaataact tctcggccgc cagataggtc
    55021 aaggagtctt gctcactcac ctcgaaacga acatttccac ctaacgaatt cgcataggcg
    55081 gcaaacgaat tgatatcgtt cagctcgata tatacggact tcaaatcttg caaggccact
    55141 ttcgcctcct cgctacccgg ataattgcta atcacgctct tataagcgtc ggccgctttc
    55201 tccggctgat tgtcgttgaa gtaaatcaaa ccaagctgta cgccggcctt acgagccaga
    55261 ctgctttgcg ggaaatcacg catcaattgc tcaaagcttg ccgcagccgc ttgattgtta
    55321 tccaataaca cgtaagaacg tcctttctcg aacaaggcat catccacata ttgtgattcc
    55381 gggaactcac ggatcaagcg atccatcacg ctgatctttc ccttataatc tttctgcaat
    55441 cccagcaaga agcccttctg atacaccgaa taatctccgg cggacggttg caattgcgcc
    55501 gcacgggtat aattctcttc cgccatagcg aactgacggt tgtggaataa acaatcgccg
    55561 atacgattat aagcgtccgc ataagccgga gtctgctgat tgctttccaa attcacgtat
    55621 tgacggaaac ggttcaacgc ctcgccatac tctttcaatt tgaagtagct gtaacctaag
    55681 ttataatgtg ccaaggcata catatccgta ttacgttggc gggtattatt caaataggta
    55741 cgataatcgg aaatcgcctt gttatactca ccttggcgat aataagattc cccacgccag
    55801 aaataagcgt cgttacgaga ttccagatta taagcgccca acgagatcgc acggctgaaa
    55861 agatcgaccg ccttatccaa ttccatattc gtgaacgcct gcgttcccaa ctggaataag
    55921 atatcttgct tcgcctccaa gatcttcgtg ctcggatgct tgatcttatc gatagagttc
    55981 agagccgctt gatagttctt ggtagtcaaa taaacctcca ccagataatc gtttacctta
    56041 tcggcatatt tggaattcgg aaaatcattc aagaaatcct cgaagattgt caccgactcg
    56101 ccaaagcccg tgaaagcggt ctcgtggatc aataaagcgt aattatacat agccgcctct
    56161 ttcacttgct tatcgaaaga agaagtcgcg gcagcctcga aggccatacg ggcgttattc
    56221 ttatctttta atttcagata actttgcccc agatacagat aagcgttctg cgaaagggca
    56281 tcgttctcac gtacggtccg ccccaaagcg ttcacggcac tactgtaatt acccttattg
    56341 taataacata cgcccaagat atataaatcg cccctcaacg ggctatccgt cgaggataca
    56401 tatttactca gcatattaat cgcctgatcc tcatttccca gatgatagta ggcgttaccc
    56461 atgatacggt aaacctcgct attgttctcg ctatccggat aagaggctag caattcctta
    56521 ccttcgctga tcactttctc gtatttattc tggataaaat aaatttgcgt gatatagtac
    56581 aaggatcgct ctttataatc aggcaagtcc ttcaagcggg taaattccac caaggcattg
    56641 ttgtatttac cggttgcgta atcgatataa gcgacataat aggtagacgc ttcccggtac
    56701 ttcgttccaa tctgctcgat ccgtgcgaaa taaccacggg ccttctccat atccccgatt
    56761 tgcaacaagg aataagccag acggaaacaa taagcctcct gttgttccgg acttagcata
    56821 tcaatgttcg attcgttaaa ccaaaagata gctttctgat actctccctg tccgaaatgg
    56881 gcggaaccga tcaagaagtt cacctcgtcc gcatgacggg aagccgggta cacatccaga
    56941 taatctttca ataactcaac ggcattggga cggccttgct cataagcgga gtagaccaac
    57001 atataatcgg cttcttgaat caagtcggca tccgtggaat gctgtttata cgcctccagc
    57061 ttatcgatgc aacctgaata attcttcaaa ctaaacaact ccttgccttc gacaaacaaa
    57121 cggttcggcg catcaaattg atacgatctc tgcccgcttg ccatgtggct gcctactacc
    57181 agacacagcg gaataagtat tcttttcatc actcatttgc tttttaatac aagcacttac
    57241 ttcagtgcct attcgttcta attcgcaaat ataagtaata tgcgccaaac agaaggcaag
    57301 ttctattaat atttaggaca acacgttcta aaattatctc tatggaagat gatacacctt
    57361 atagggagaa gatgtattat cttacaacga caagatgtat catgttgcaa cgataagata
    57421 tatcatcttt cattttcgta caattttcct aattgttatt ttctaagata ggctggtacc
    57481 gcctttcgga tagagtctaa accgaagtct tccggattca cattctccgg gcgaaggatc
    57541 acgatctcgg cggcatcatc ttccgcatgc acgttattga aatcatctac caagcactca
    57601 taaaacatat ccagcgtatg cacctcaaag ccggaataca tatataaatt aggcaaggaa
    57661 aacaaataac ggcaattctg gatatgcaac cccgtctcct cccttacttc ccggcgagcg
    57721 gcctcctccc ccgactcaaa catatcgacg aagccaccgg gcaaatccaa tgtaccttta
    57781 gccggctctt ttcctcggcg aaccagcaat aactccccct tagcgttctt tatgaaacaa
    57841 gcgacagccg acgacgggtt gaaataataa acaaaaccgc acgccataca ttttttcgct
    57901 ttctcgttat gttccacgaa agcttttgcc ccgcaaaccg ggcaaaactg aaattgatac
    57961 aacggatgtc tcatacttta tgatttataa ttcaattaaa aacaacaagc cgcacctaaa
    58021 tatagatgcg gcttgcctta tttcgcaaat gtcttttcgt tatacgtaaa accggattta
    58081 gacttccaaa ccagcgcttt ggtctcttac ttcccaaccc aaagcacttg ctcctaatac
    58141 ggcagcgtcg ctctctttca attgagagaa taataattta gtcttacctg cgtaaacctt
    58201 caacatattt ttctccattg aacgtttaat cgggttcatg atcaaatcgc cagctttcgt
    58261 aagaccgcca aacaaaatga tagcctccgg gctagagaat gctacgaaat cagcgaaagc
    58321 ctctcccaac atagagccgg tagcctcgaa aatctcaaga gcgatcttat cattcttcat
    58381 agctgcgtcg tatacgtctt ttgaagtgat ttcatccgga tccaagtcgc gaagaacact
    58441 ctcgtcctta cggatttcca gatattcacg agccgtacga gccacaccgg tagctgaagc
    58501 ataagcctcc agacatcctt ggcgaccgca accacactga cgaccgttgt tacgacgcat
    58561 gataacgtgg cccaactcac cggcaaaacc gtcatgtccg tataccaagt taccaccgat
    58621 tacgataccg ctacccacgc cagtacccaa agtgatcacg ataaaatctt tcataccgcg
    58681 agcggctcca taagtcatct caccgatagc ggcagcgttg gcgtcgtttg ttaaagcaac
    58741 aggaatacca tcgatctgtt cgctgatcaa ttgagccaaa ggaatcttac ctttccaagg
    58801 caagttcgga gcgaattcga tacatccgtt gaaaaagttt ccgttcggag cacctacacc
    58861 cacaccttta atcttatccg gaccaccagc ctgatcaata acagacttca gacctttagc
    58921 taattccgct acatagtcat taacgtctgc atatttacca gtcttaattg atccactata
    58981 caagattgtt cctcttgcgt caactacacc aaaaacagtg ttggtaccac ctatatcgat
    59041 acctactaca taaggcttct ccatgatttt atatttagga ttaataatga ttttcctctt
    59101 tctaggtagc aaatataaga ggtttaacac aagttgcaat acgatttgaa gaaaatttta
    59161 cagattcctg tcattttatc ttcttttttc gaaaacttat gttaagcaac attgttatat
    59221 aataatggag aattatcgca acggtaatat ctcgatccaa tagtcatccg gatcattaat
    59281 aaaatacaat cccatcttgg tattctcgaa gcaaaccgct cccatttcct tgtggtattt
    59341 acgtacctcc tcataatcgc cggctacccg gaaacaaaga tggctctcat tgtcgcctag
    59401 ctcataaggt tctttccggt cacgcagcca agtcagctcc atcaagaaac cggtttgctc
    59461 atccgttaga taaaccaaga taaacgaacc gtcttccgct accttacgat ggtgctcttt
    59521 caatcccaac gctttattat aaaaagcgat actcttatcc aaatccaata cattaatatt
    59581 gaaatggtca aatctacctt taacttccat acctaataaa tttatgcgtt taaaataacc
    59641 tatacattaa taatatatta tatatccgtc ccttctcccg gaacagacaa tacgatataa
    59701 cgacatcctt tcgattcggc gtaagggccg aaagccataa cctccgccgg acgttcccaa
    59761 aagtgcatcg ggacaaatac gcttgttttt atacgatcga taaattgctg ggcgcccctc
    59821 atgaaatcgg tacccaaacg aggatcgacc gggaacatga cgagatccat cacagaggtt
    59881 tctttcgcta ttatatccag ttccttcaag taattaccct cagcctcggc tacctcttgc
    59941 ggggtggact cgtctttcca atgccaatta ttcaagtcgc cggcatggaa gatccgtctg
    60001 ccttctgtct ctatcaggaa agagatcccc acatccgtgg aaccaaatgc cttgatggtc
    60061 agaagttcat cttgataggc atcccccttc ttcaaataaa tagcatcatc agccttggcc
    60121 ctccgacgct tcaatatatc cttggaaaag atatatttga tatccggctt ctgctctttc
    60181 catttcaata cttccggatg aaaatgatcc ggatgaaaat gcgacgctaa tatatataat
    60241 gtgcccgcac gcttcaagag ttcgctacgc acgtatccct tggccgggtc cggatcgcta
    60301 tccttgaaat aatcgatcaa gatcgaaaag ccatccgctt ccaaagcgaa tccgctatga
    60361 taaatataca ccaatctcat aatgatcctc atttattgtt tatcttaaga acaccgaacc
    60421 tcaccgggtt gttgaattca cggtacaaat atacaaaagg ccggacatat cacatgcccg
    60481 gcccacaatg attatcaact tacaatttat ttccagttct cattctggac taatacgcct
    60541 tccatggtga caatttcatc gttagggatc ggaagtgtca ctaatctatc cggatacgta
    60601 gccgattggt acttcagcaa atatctcttt tcataagcca agaagcccga acctttatta
    60661 cccagctcct cagaagccgc attccagcgc acaagatcat accaatgatg cccctccatc
    60721 gccaactcga tcctacgctc gaaacgcaag gcttttatcg ccttatccac tgtccagcca
    60781 ctcgcaggat acaagccgat gcgataatta gccgccgtat tagcaatggt atttccgctc
    60841 accttatcct ccaatacata tggagaagaa gttaaagcca tattgttatt cgcgtcggca
    60901 gccatgatac aactttgtgc ggcacgtgcg cgaactttgt tgatatattc tctggcagta
    60961 ttgatatcac ccgtttctat acaagcctca gcataaagca ggtaaagctc agctacacgc
    61021 atcaagtgga agttcttggc agttgagcca ccggttgtag tcaagctcaa gcctccctta
    61081 tccgcctttt tcggcaggtt cttcttattc aagaacggac cgccattcgc caaatcacga
    61141 atccagccat cgatagtaac tggtatatcc caatccatat agggcacatt gaaacgaccc
    61201 gcagatacat caacccgagg atccgtataa accgtcaaat ccgtatgagg tacattatcg
    61261 ccatcaattg tcgtaaccga ggttttgctt tgatacgact tatcgagata aggcaatcca
    61321 ttctcatcca ccatatgcgc attcaccaag tcataagaag gctggtagaa tccccagccg
    61381 gaaccaatct tgccagacaa tgagatatga gagttaccat tgatcgcgtt ggtataatac
    61441 tgcgtaccgg agattgccat ctggacgtca aacacagact cgcccgtcca gtcgctctcg
    61501 cccgccgtgt aaagcgtctc ataactcggg gtcaaggtat atttcgtgcc cttgctatcc
    61561 gtaccattag cgataaccgt ttctaaaatc gatttagcct ccgtccattt gttggaggtt
    61621 ccattcgttc cattataggg agaagactgg aatattctca gtttcgccaa aaacgctcca
    61681 gccgcccatt tgttggcacg accgggctct tccggccatg cgccgggaag attatcataa
    61741 gcatactgca aatcttcagc cacctgttcc caaatataaa tatagttacc gctctcatcc
    61801 acattcgata tcagtgggtt cacggacgac tcataatcct ccaaagatac ataaggaata
    61861 gccgccccaa aattcttgat accctcaaac aaataaaaac cacgcatgaa acgagcttgg
    61921 gctatggcct cggtataaaa atctttctcc tgtcccggta tagcggaaag ctcatcttta
    61981 atcaaaccgg ccaaatgcat gacattatta gcacgagcca ccgcatcgta tactgccacc
    62041 catttacgct tgatatagga attatcggtc gtaaagctaa aagtctccaa caacgtgaag
    62101 tccgattggt ccgcagccgt tgacccctta ttagcgtcac cgcccatcac atcaccatac
    62161 gtatagtttg tcaagcttgc cccaaaataa gagttagtcg tagccgccgg aatatttaac
    62221 gctgaataca tgccggtaag aagataatta ataccttcct gatccgttaa attggtttca
    62281 ttaaccgcac ctactggttc gatctccaag aaatcggaac aagatgtgct gcctaacgcg
    62341 agaaccaccg ccatcgcaaa atatataaga acttttttca taatgaattc aaattaatcg
    62401 tttataaagc acatacgtta gaatgtcaca ttcacaccca tcaagaactg acgaggcata
    62461 ccataagatc cataatcgat acctttattc atatcgcttg atacatattc gttctcgaac
    62521 gaagtatgcg aacgaacctc cggatccaat ccatcataac cggttatcgt aaacacgtta
    62581 ctgatctggc cgtatacacg tatcttctcg aaaccgatct tcttcagcaa cttcttaggc
    62641 aatgaatacc ccaaagtcaa cgtctgcatc cgaagataag aaccatcttg cacataattg
    62701 gagttcgatt cgttaccagc ctcggggccc tcggtcgagg tcgttgtcca caaaggataa
    62761 ataccgttcg gattattcac cggatcccaa gatttcgcca aacgatcttt cgaataatta
    62821 gactgcaagt ttccaaacat cgtatagtac tcgtagtgtt tgtacaaatc atttccaatc
    62881 gagtaataca tgtaagtact tagatcaaaa tctctccaag tcaaagagat attgaaacct
    62941 ccggtcaaat caggatgagg attaccgata atcgtacggt catccgcgtc gatcttacca
    63001 tcgttgttca cgtctttcat cttatatcgg cctacccatg cggaagcgac caaatcgttt
    63061 tccgtagcca caccataagg cagaacgccc gaggaaataa catcttgctc attttgataa
    63121 ataccctcaa tctgataccc gtagaacatt ccgacaggtt ggcccaccgt agtaatattc
    63181 accttgctca aacgagtatc gttgaacaaa tcagaagatc ccaaccgggt aacctcattc
    63241 ttgtatcttg agatgttagc cgtgatgtta taaccgaact cgccaacttt gtccctccat
    63301 ccaatggaca aatcaacacc tctgttcttc atatcaccga tattgatact aggctttgat
    63361 gcgttaccaa ccagcgcaga ccagttagca ggcacaagca agtctgaggt attctttaca
    63421 taaaagtcaa atccggcggt caatcggtta ctcaaagccg taaggtcgaa acctatatta
    63481 aacatttttg tggtttccca tttagcgtcc gagtcaccca agttcgagag cacataaccg
    63541 ggagaagtct ctgaatccga tcccgtgata ggatacatat aataatttcc cgtaccatac
    63601 tggaacgcat agttgtaaga accaatattc gaattaccgg tcgtaccata accggcacgc
    63661 agcttaaagt catccaacca tttccgggta ggctccataa atttctcgtc agacatacgc
    63721 catcccaagg aggcggaagg gaagttaccc caacggttct tggagccaaa cttggaagaa
    63781 gcgtcgcggc gaatcgtgaa tgtcgccaaa tatttaccct tataagaata gtccgcacgt
    63841 ccgaaaaggc cgaacatagt cacttttctt tgataacggc tagagttacc tatattagaa
    63901 gaagaaccat tatccagtgt ccaagtattc ggatcgctct cgaagatgta atcgatacgg
    63961 gttccttgca tataacggcc gacaccttgt ttgatagcct ccgtacccaa aacaacggta
    64021 atattatgat cttcatgaat cttcttggta taagtagccg tatttgtcca ctgccagttc
    64081 aaacgccagt tgcccgtctc agtcaatgta ttgttggcag aagcctcttt gttcgccata
    64141 ttttgacgtt cggtcatctc caaactccac ataccattca agcgagcgct aaactgagaa
    64201 cgaagcttca gaccttcgat ccaaggattg gaaagctcgg caaaaaccgc agtctgtcca
    64261 tgaaacatgc gtgtccaatc attctcattc atagctacct gatgcacggc ggaaatatca
    64321 cggcccgcat taggtgccac ggatcccgta taatcacctc ctacattata tataggtacc
    64381 cacgaattca tggtataagt cttagcgaac gtgttcgcat ctccttgacg accagactct
    64441 cctcccgttt ccatagcggc aaggttcgta ttttggccca tcgtgaaata cttattagga
    64501 ttataggtcg tattcgtacg taaagagtaa cgtttgaaat aagaattctg gatcgtaccc
    64561 tctcgatttg tataacccaa agagacagaa taagtagctt tctcgccacc acccaccaaa
    64621 gagatctggt gatcttggat ctttccggtc tgtacaatct catcgtacca attggtaccc
    64681 ttacgagcct ccgcatcgga ataaccgtcg gccaacatct gataatacgc ggatcgggcc
    64741 caagagctgc ttccatcgtc tacatacgac ttttcccaag cctctacgct cccatacata
    64801 tcaataatct gctgttcgct ataaccggcc ggcttaatcg cataaggcat cgaaatacct
    64861 ttaccacccg tagcggcgat ttgcccgaat tgaggatgag aggttgccaa accacgatag
    64921 ttatacagat tctgctgtcc taattcctcg aattccatcg attcccaacc gttcaacaaa
    64981 tcataaccgc tgttagccat cttagcgaca ccaaaatatc cattataaga gacacgaaca
    65041 cgatcagcac gcgtaccctg cttcgtcgta atgataatta cgccattcgc accttgtgca
    65101 ccataaatag cggtagctga agcatccttc aacacttgca tagactcaat atcattcggg
    65161 tttacggaac tgatatccac tccggataca ccatccacaa caatcaacgg gtctgaacta
    65221 ttaagagaac ccacaccacg aatacggatc gtagtctcac cgctgggacc tccggaatta
    65281 gagatataca caccggatgc ttttccttgc aaagcctcgg cgaaagtcgc caccggagtc
    65341 tcgtggatag cgtctgtaga aacaacagca acagaaccgg taatgtcctt cttcgattgc
    65401 gtaccatatc caactactac cacttcatcc aaagcttgag tatcttccac caattgaatc
    65461 ctcacattcg tctgactact ttttaaagga atttcttgac tgacatagcc aatgtaagac
    65521 acaactaaaa tcgcattact aggcacacct tctaaaataa cacgtccgtc catatcggag
    65581 atatttccga tagtggttcc tttaacaagg acatttgccc ctacaattgg tccggctttg
    65641 tctgaaatag cacaaatgac tctacgtcca tcttgttgta ggctacgagt tcctacgttt
    65701 ggtgttaaat cgccaacttc cgcagcgatg atgggatatc cgccgcaaag gaataaagag
    65761 gctcccagaa acacctgtct ccaaaatact acattactca taaaattaga atttaaggta
    65821 taaatcaaaa aaacacaatc tacttaacaa tttgattttt tcatatagac acaacatcac
    65881 aacttgtagc tattactcat ctatcttatg gtctaaatgt tttttcataa aacgactagt
    65941 tgaaacgatc gtttaaatct tgcgttttcg agaaggggga aagaggattt gaaaaagaag
    66001 agcttttttg tgggaagaaa aggttatctt tcccattagc aataagataa aataaaaaaa
    66061 aatgaacaaa aagttgcatg tgtcaaaaaa aagacagatc tttacaaacg actaaatgaa
    66121 acgatcgttt caactagtcg ttttttttaa tatcatgaaa aaaacaagaa gtgattttca
    66181 taattaaaac catgataatg aagaagctac acaaaagaag ttgaaaagaa gagagtgatg
    66241 tttacttatt ttaagatgta aacagatgta atatacctta gaggtatgag agagtagtga
    66301 attcattttg ttaaaagttt gtgtttttta ttttattata ccttaaattc taaatttgta
    66361 tgagaaatgt tgtatcatgg aagccattag tcttaggagc ttcttttctt ctgtacggag
    66421 ccggaacggc ctttgcaaca gaaacagatc atctgtatcc tacacctagt acgggattta
    66481 tgagtgtcca gcaagatgga cgacagatta actgccacat cgtggataaa tctggtccta
    66541 tcgttggagc caacgtagtc gtaaaaggaa ctactatcgg aaatatttct gatatggatg
    66601 gacgagccat tatagagaat gtgcccgcaa acgccatctt agtagtctct tatatcggat
    66661 acgtaactca agaggttact ttgaagagta atcagacaaa catcaagatc acgctggtcg
    66721 aggattcaca agctttggat gaagtcgtcg ttactggtta tagtacacaa gcgaagaagg
    66781 atattaccgg atctgtggct gttgtcgcta cggatgagtt aaaagagact cctgtttcca
    66841 atttcgctga ggctttgcaa ggaaaagctg ctggtgtatt tgtacaagca ggtggtggtc
    66901 cattagggga gacaacgatt cgtatacgtg gtgtgggttc cgtaaacggc tcagacccgt
    66961 tgatcattgt cgatggtgta caaggagtag atatcgatgc ggtaaatgcg aatgatattg
    67021 aatccatgca gatattgaaa gacgctgctg cttccgctat ttatggagcg aaaggtgcaa
    67081 atggtgttat cgttatcacg actaaacaag gaaaaaagaa cgaccgtgta caagtatctt
    67141 ataacggtta cttcggtgta gccaagatgg ccaatgacgg ttatggtctg ttgaacgctt
    67201 gggaagctat ggaattccaa gaagaagggc aacgtaattt attcaactac cgcggtggcc
    67261 aaacagtaaa ccacgcccag ttcggttcaa taggtaaaga cggtacaggt catttaacaa
    67321 tgccttatgc tatcaaacct gctggttata gtaaagaaca gatcatctct caatacggca
    67381 gtatcgcagc ttgggaagct tcttacaaag acaatggtga gaacacttgg tctcgttccg
    67441 cttactacca aatgcttgag gacggctact ctgaggaaga agctcgtgcc ggcacgaatt
    67501 ggtacgacga agtagttcaa accggtaagg tgcaagatca ccagatttct atcaccggag
    67561 gtggtgaaaa agcgacttat tcagtaggct taggctacat gaatcgtgaa ggtacgatca
    67621 aggagtcatg gttccgtcgt tattccttgc gtgcgaatac aaacttcttc gtgaacaagt
    67681 ggttcaatat cggtcagaat accaacatcg ccgtaatcga gaactcagga gaacgcggtc
    67741 gtcaaggtga tgataatacc ttcggtaaga ccttctccat ccaaccttgg gtacctatct
    67801 acacagttgg cggtgattat tccggttcac aaaatgccga aggaggacgt gctgagagcg
    67861 caccaatgtc cgttgattat ggcaaggaca atcgtcgtcg tttcttacgt gcccaatcag
    67921 ctatctacgc agagattatg cctttagaaa gccttggaga gaatttgaag atccgtactc
    67981 agttcagcgc acgtttaggt ggcgcatggg acttctggat gaacaaacgt acgatcatga
    68041 ccaataaaga aggacgtaac aacaacgagt tctacgagca agcaaactat tggttagatt
    68101 atcaatggac aaacaccgct acttatagca aaacaatcaa cgacgatcat acgatcaatg
    68161 ctgtgattgg tacagaggca cttcgtgagg gtttaggacg ttggatccag gcaggtcgta
    68221 tcaactatcc attcgaagat gatcccaaca cttgggtaat caacaacggt gctagctctg
    68281 acttaagaaa tagcggaaac cagaacgctg tatccaccat gttcggtatg ttcgctcgtg
    68341 cggactatgc ttaccaaggt aaatatttgg ctacagttac ggtacgtcgc gacgcatcct
    68401 ctcgtttttc tgaaaagaat cgctggggta cattcccttc tatttcttta ggttggcgta
    68461 tgtcggacga gaaattcatg gagaaatcac gtacttggtt agacgatttg aagattcgtg
    68521 ccggttacgg tacaaccggt aactccaata tcgattcata taactgggca ttccaatatg
    68581 gtactggtaa ccgttatctc tatagcatca atggttctga cacagaggta tatcaaggat
    68641 ttggcgtaac caatcttggt gatatcgagg caaaatggga aacatctaag atgtttaatg
    68701 caggtttcga tattacagct tttaatcaac gattaaccgc caacttcgac tactacatca
    68761 agaaaacttc tgatatgttg atcgatgcca actggtctgc tttggccggt gccgctgaca
    68821 agccgaaagt aaacatcggt gatatgacga acaaaggtgt tgatttgaat attacttgga
    68881 atgataaaat cggtgaggta ggttactctg taggcgtaaa cttgtcgcat tacaagaata
    68941 gactggatga gattggtact gatgccggaa tctttaccgg aactcgtatt tccaacatga
    69001 acgtattgat gaagggacat gcaatcggtg aattccacgg ttatcagcta gatggtatct
    69061 ataagagtga agaagaagtc cgtaactata agaatgatgc cggtggaaca gtattgccat
    69121 atggtacatc tgatgcttct acgttaaacg ctgccaatta tgtaggtcag ttcaaagtaa
    69181 aagatgtgaa caacgatggt aagatcgacg ctagtgaccg tacattcatt ggaaacccac
    69241 atccggattt aacaggaggt atcaacttag gtgttaactg gaaaggattc gacttaagta
    69301 cttatatgta cttctccgta ggcaatgatc tattcgccat gtataaatat tatacacatt
    69361 atggttcctt acagtccgct tattctaaag atcgtcgcga caattcatgg catcctgtaa
    69421 ccaaccctga tggtatctat cctatgtggg caaccgctaa tggtgagagt acaatcgccg
    69481 caaatgagtc taattccggc tatatagaag atggttcatt cttacgcatg caaacgttga
    69541 ctttaggtta tacacttcca aagagtattt tagataaaat caagtttgag aagatccgca
    69601 tctatggtca aatagcaaac gtattcacat tgactggtt
//
LOCUS       DBMDTB010000008        68736 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_180_length_68736_cov_11.889910, whole genome shotgun sequence.
ACCESSION   DBMDTB010000008 DBMDTB010000000
VERSION     DBMDTB010000008.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 68736)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 68736)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68736
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_180_length_68736_cov_11.889910"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            76..894
                     /locus_tag="ACZPB4_02510"
     CDS             76..894
                     /locus_tag="ACZPB4_02510"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HIR1097129.1"
                     /translation="MKKIYLFLFSLFICNILAAQDQDYKIVRDISYTQSKDPYAVERC
                     KLDLYYPENAKDFPTVVWFHGGGLSGGSKFIPEELKNCGLAVIAVNYRLLPKATLSDC
                     IDDAAAAVAWTFNEIEKYGGDRRKIFVSGHSAGGYLTNMVGLDKKWLTKYRIDADAIA
                     ALIPFSGHAISHFAYRQAKGMKDTQPSIDEFAPLFYVRPDAPPLIIVSGDREMEMLGR
                     YEENAYFWRMMKVAGHKNTYIYELDGYDHGSMAAPAFHILKNHVRMILKGSETR"
     gene            921..2366
                     /locus_tag="ACZPB4_02515"
     CDS             921..2366
                     /locus_tag="ACZPB4_02515"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004348 - glucosylceramidase activity
                     [Evidence IEA];
                     GO_process: GO:0006665 - sphingolipid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 30 protein"
                     /protein_id="HIR1097130.1"
                     /translation="MVLFSLLMVLICLNACSGAKISDNVTVYVTTNDRAKDFVRSEIA
                     LGDKQAASPCVITIDPSVRYQTMDGFGAAVTGSTCYNLMRMAPEDRTAFLKETFSDTE
                     GMGYSYIRISIGCSDFSLSEYTCCDTKGVENFALQSEEKEYVIPILKEILAISPSIKI
                     LGSPWTCPRWMKVDNLKDLRPFESWTSGQLNPAYYQDYATYFVKWIQAMEAEGIPIEA
                     ITPQNEPLNRGNSASLFMGWEEQLSFVRDALGPKLKETGLKTKIYAFDHNYNYDNMLE
                     QQGYPMKIYEDENAASFLTGAAYHNYGGDREELNNVNGKFPDKELIFTETSIGMWNDG
                     RNLEKRLMEDMEETALGTVNNWCKAVIVWNLMLDNERGPNREGGCQTCYGAVDIDRSD
                     YKTITRNSHYYIIGHLSSVVKPGAVRIGSKGYTADGIMYSAFENLDGTEALVLLNNTD
                     GTKNITVNSGERSFTYEVPAKAVASFRWNLY"
     gene            complement(2529..4154)
                     /locus_tag="ACZPB4_02520"
     CDS             complement(2529..4154)
                     /locus_tag="ACZPB4_02520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HIR1097131.1"
                     /translation="MKNINETVKSKYLIYILFLAGGLLLGWLLFHNSDTDSHTSQASE
                     TGTEVHAPTHGHDLQQNEAGEWTCSMHPQIRQDKPGKCPICAMDLIPVRKSSFSDKAI
                     DPNAIQLSEEAAALADVQTSKVSRQNPVKQVRLYGKIVPDERSLQSQTAHVSGRIESL
                     NVDFTGETVRAGQTLATLYSPELFTAQQELLEAIRMGQSQLIQAAREKLYLWKMTDAQ
                     IAAIEKSGSISPVVEIKSNTSGIVLSKRVSQGDYVSQGAILFDVANLTKVWALFDAFE
                     VDLPFLSKGDPVEFTLQALPGKKFSGKISFIDPILNTTTRTAKVRVEVPNASLELKPE
                     MYATANVSAPLRNYKNEIVVPQTAVLWTGKRAIVYVKQPDTNTPAFLMREVELGPSLG
                     NSYVILNGLREGEEIVTNGVFAIDASAQLEGKTSMMNNGDEPAKPMIGHEGHMMHAQS
                     ATGVASEHAMFGVKGSCDMCKERIEKAAKEVNGVLSAHWDKDTQMIHLQYDPQKTSPK
                     AISKAIAKVGHDTDMDKADKAVYDKLPACCHYR"
     gene            complement(4159..5625)
                     /locus_tag="ACZPB4_02525"
     CDS             complement(4159..5625)
                     /locus_tag="ACZPB4_02525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HIR1097132.1"
                     /translation="MAGVLGMLNVLFAYSQPADSLGYYLELAARNNPQINADFSLYKA
                     SLEKVPQAGAYPDPELEIGFFLKPMEILSGKQIADFTLMQMFPWFGTRKAARNEATEM
                     ARMAYEQFRNSRNNLYYEVKSQWYQLCNISEQYKNTQANLRLLDQLEQLALNRFSAPS
                     AKAGGSSVLPSPVSSAPSTPPAVSGGGMSGMGGSSMGSPTVQSTGASGSTMSGMSGGS
                     PMGGGSMGSGNSMGGMSDVLRIQMEKVELENTLASLLSQRKTAEAAFNTLLNQSLATP
                     ISVPDSLERLPLSWSESMALDSVISNNPMLTMLEAEGNAYRAKAEMDKKMSYPMLGIG
                     LQYSLIGKKPEDMSMGSMSGMNGKDMFMPMLKISLPIFRKKYNAQQRESKHYWKSSEL
                     KYENTMNQLQAEYIRITQQLEDAARKIDLYQKQYDLSLATYQLIVREFSTGRTTLTDV
                     IQVERQMLDYHLKKSEAIAEYNTQIAGIEKLISTSVNE"
     gene            complement(5645..9391)
                     /locus_tag="ACZPB4_02530"
     CDS             complement(5645..9391)
                     /locus_tag="ACZPB4_02530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HIR1097133.1"
                     /translation="MLNRIIRYFLENRVVTLLLLVLIIVWGISTSPFNWHGGIIPRNP
                     IPVDAIPDIGDNQQIVATEWMGRSPKDIQDQITYPLTTSLLGIPGVKTIRSSSMFGMS
                     FIYIIFDDDIEFYWSRSRILEKLNSLPPGTLPEGVQPTLGPDATALGQIYWYTLEGRD
                     PKTGKPTGGWNAEELRTIQDFYVKYTLSSAEGVSEVASAGGFVKEYQIELNPDAMYAF
                     NVSVMDIMSAIKKSNLDIGAETMEINKVEYLIRGLGYIKNVKDIENAVITVREGVPVR
                     ISDVAFVNIGPGTRRGGLDKEGVEAVGGVVVARYGSNPLEVINNVKAKIKEMEPGLPQ
                     KVLADGTVSKVTVVPFYDRTGLIKETIGTLETALSHEILICVIVIIVLVLNLRASIVI
                     ASMLPIAVLATFIIMRYTGIAANIVALSGIAIAIGVMVDVGVVFVESIIRYREMPENR
                     HIQGGKAFVNLIYKAVSEVSGAISTAMITTIVSFLPVFTMEAQEGKMFSPLAYTKTYA
                     LASAFVLGLILLPSLSYWLFSIKIHSRQIRKILNYLLIVAGIALLIIYGSIPAIGLTA
                     VGVNNLLSGYWKKPQMSTYINIGITLFVTIYYLSEEWLPMGPQKGMLANILFVAGCVA
                     IILSILWLLVIYYERILRWCLDNRWKFMLIPGATIVFGFWIWRGIGQEFMPSLNEGSF
                     LLMPTSMPHSGIEQNLDYIEALDKRLASIPEVETAIGKWGRVNSALDPAPVQMFENTI
                     NYRPEYILNEDGKRERFKVNRQGEYLLKDGGVYNPKDGFRLIPSDSLIPDAKGDYFRQ
                     WRPEIKNTNDIWQQIVNVTHLPGLTSAPKLQPIEARLVMLSTGMRAPMGIKVYGPDLE
                     TIEKAGKAIEKALKEVPSVIPSSVFYDRAVGAPYLEIELNRENMARYGVNVEDLQEIL
                     SAAVGGMVLTRTVEGRERFPVRLRYARELRDNPEALGMILVPTATGAQVPLKELADIN
                     YTRGAQMIQSENTFLVGYVIFDKLAGKAEVDVVKEASRILEQQIKEGELNLDPGVSYK
                     FAGNYEQQERATSRLMIVVPLALLIVLLVLYFQFKTVTASLIHFSGVFVAFAGGFILL
                     WLYGQDWFMNFSIAGENMRDLFQMHTINLSVAVWVGFIALFGVATDDGVLMGTYIHHV
                     FLERDPRTKHDIREAVVAAGLKRVRPAAMTTATTLIALLPVLTSTGKGADIMVPMAIP
                     TFGGMLIQSMTMFVVPVLQCWWRENAIKKEQKNKIQEEVTTYEI"
     gene            complement(9652..10038)
                     /locus_tag="ACZPB4_02535"
     CDS             complement(9652..10038)
                     /locus_tag="ACZPB4_02535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HYC_CC_PP family protein"
                     /protein_id="HIR1097134.1"
                     /translation="MRRFLLFILAVFYLGVSSGFALNYHYCMGKLAEVSLQYLDTCPS
                     CGEAGTSHKCCSTETEYVKLSVDQDVANTLVQLSAPVAVVLLFDLLDSYKIAGRDETT
                     RSNPFINPPKENSAIPLFVHHCTFLI"
     gene            10182..11465
                     /locus_tag="ACZPB4_02540"
     CDS             10182..11465
                     /locus_tag="ACZPB4_02540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DcaP family trimeric outer membrane transporter"
                     /protein_id="HIR1097135.1"
                     /translation="MRLFVQGAVLLLGMGFLSAPAKAQKVVIEDDVPNSIVLVSQDKA
                     GDEIVRIMNETQSPRFHDPKAPRFVLTDRKGRFALGIGGYVKATAEYDFGGISDDVDF
                     YPSMIPNGGQNYVRNQFQMDATTSTIFLKLMGRTKHLGDFVVYTAGNFRGGSKVFELQ
                     NAYVSFLGFTMGYDYSTFMDLAALPPSIDYAGPAGQVFSRATLLRYERAFGKGWKAGV
                     GIEMPVVDGITNQSVNISNQRMPNFPAYIQYAWNKSSHIRVAGIVRNMTYENLVAQRA
                     ESKAGWGVFAASTFNVTSKLNFYGQATYGRGISQFLNDISNLDVDLVPDPEAKGKMQV
                     LPMMGWYAGLQYNITPKVFVSSTYSQTRLYSENDYPVTPSDQYRYGQYLVANIFWNVN
                     ANLQVGAEYLRGWRTDFNDMTRHANRLNVSAQYNF"
     gene            complement(11547..13118)
                     /locus_tag="ACZPB4_02545"
     CDS             complement(11547..13118)
                     /locus_tag="ACZPB4_02545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010185117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HIR1097136.1"
                     /translation="MDNDLLDITKLRRWRIWKLKLIDARLYFVSIFVGLLTGLVAVPY
                     HYLLQQLFNSRKLFFDGHYPWYFHVLFFFTLWGILLCVNWMVKKMPLITGGGIPQTRA
                     VINGRITYKNPLTQLIAKFTGGILAISAGLSLGREGPCVQIGSYVGNIISKWGHVLAG
                     ERKQLLAAGAGAGLAAAFAAPLASSLLVIESIERFDAPKTAITTLLAGVVAGGVASLI
                     FPFNPYSQISAIAPQATFIDQLKLFLFLAVVISVFGKIYSMFTLWCKDFFTRLKHPPY
                     MKMLYLLIIAYTISLTEIDLTGGGEQFLIMQAMHGYHPVLWIAAMMLIHLIFTSLSFS
                     SGLPGGNFIPTLVTGGLFGQIIALLLVKYGFIETESISYIMLISMVGFLVAVVRTPLT
                     GIVLITEITGHLDVFYPSIIVGGLTYYFTEMLQIKPFNVVLYDEMISTPAFRTEGRSS
                     LFVEIMTGAYFDGKEVDHLTLPQRCIIKTIHRDRKDLAPAGQTLIPGDQVEIEIDSQD
                     IEKLYEPLISMANIY"
     gene            complement(13300..14298)
                     /locus_tag="ACZPB4_02550"
     CDS             complement(13300..14298)
                     /locus_tag="ACZPB4_02550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gliding motility protein GldB-related protein"
                     /protein_id="HIR1097137.1"
                     /translation="MVTKLIMACILSATLLSCNGQNTNTINYATVEPLHINRFDKDLF
                     RLIDTEDTTLQPELIKQYPEMLDIIGKGILNLQTIETPGFFEKMRNYYSEPTLKGLYR
                     DAITQYDSVEDIEKSLGYGFAYLKENFPSMQIPAIYMHVSGFNQNVLVGDSLLSLSID
                     KYMGKDYPLYQDFFYDSQKLKMQRGLVVPDYLAGWLMSEYPFAGKENVLLDRMIYEGK
                     IKYLLSQALGVPDAAELMGYTEQAYNWCKDNEGTIWKAIIERKHLYTPDQLTTSQYFE
                     DTPAIFPENDAPGNIGTWIGWQIINQYMKETGSTPEALMQNNDAQEILTASKYKPL"
     gene            14407..15729
                     /locus_tag="ACZPB4_02555"
     CDS             14407..15729
                     /locus_tag="ACZPB4_02555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HIR1097138.1"
                     /translation="MRYTNKQILKITYPVLISLLMEHMIGLTDTAYLGRVGEVELGAS
                     ALAGVYYLVIYMLGFGFSVGAQVLMARRNGEGEYKRIGEVFTQGGLFLFLLAAVLFTA
                     SNLLTPHLLHRMIGSEEVYRATMSYLDWRVYGFFFSFIAVMFRAFYVSTTNTKILTAN
                     SVVMVLTNVVLNYILIFGKFGFPALGIAGAAIASSISEAVSVLFFVIYTWKKIDYKKY
                     GLFRFTRVDFRMLGQILSVSIWVMIQHGIAFGGWFIFFIAMEHLGERPLAITNVVRSI
                     SSFLFMFVNAFASTNSSLVSNLIGAGESDRVLPLCRRMIGLCYAFVLPIGILIAMFPS
                     TVLRIYTDNPDLIASSISSLWVMLSSYLFAVPGFIYFFSVSGTGNTRRALEIDMASIF
                     VYVLYILYVAVWLRADVAVCWTTEYVYNIMILSSFFYLWKGNWRNKKI"
     gene            complement(15734..16858)
                     /locus_tag="ACZPB4_02560"
     CDS             complement(15734..16858)
                     /locus_tag="ACZPB4_02560"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003689 - DNA clamp loader activity
                     [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit"
                     /protein_id="HIR1097139.1"
                     /translation="MYFKDIIGQEEVKERLRQSTRTGIVPHAQLFTEQGGAGAFPLAL
                     AYARYLNCTNRTETDACGRCPSCLKYDELAHPDLHFVFPIVAKKEKKKEVCDDYLSEW
                     RGFLKEHPYFNMDEWLDYIEAGNSQAIIYSKESDEIIHKLSLKIYEAEYRILMVWLPE
                     KLHPTCANKLLKIIEEPPMKTVILMVSETPDLILGTIQSRAQRIHIRPIETDAIMNAM
                     VSRFGLSPDDAKHVAHLSSGSFIKAMEAISLGEENKFFLEQFKAMMRNSWARNVKGMK
                     AMADVMAGIGRERQKNFLSYCQHLIRENFMYRFQSPELNYMNLDEASFSVKFSPFVNE
                     RNVIDLMEELAKAERHITQNVNAKMVFFDLSLRITVLIKR"
     gene            complement(17113..18066)
                     /gene="metF"
                     /locus_tag="ACZPB4_02565"
     CDS             complement(17113..18066)
                     /gene="metF"
                     /locus_tag="ACZPB4_02565"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004489 - methylenetetrahydrofolate
                     reductase [NAD(P)H] activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HIR1097140.1"
                     /translation="MKVIDLIRNSKSTAFSFEILPPLKGNSIQKVYNVIDKLKEFDPK
                     YINITSHHSEFVYKTLPDGSFQKVNIRKRPGSVAIASAIQNKYGIPAVPHIICKGFTK
                     DETEYALIDLNFLGVNNLLILRGDIKTLEASQQKPELYHDHATDLQQQVNHFNEGIAL
                     DGSKIDGIETPFSYGMACYPEKHEEAPNMESDIYYLKEKVKNGAEYLVTQMFFDNDKY
                     YAFVDRCRAEGITVPIIPGIKPIVFKNQLTVLPKIFRADIPEPFATELRKCKDDAEAK
                     EVGVEWCIQQCKDLIAHGVPSLHFYTMMASDSVYKIAKEIY"
     gene            18187..21426
                     /locus_tag="ACZPB4_02570"
     CDS             18187..21426
                     /locus_tag="ACZPB4_02570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA domain-containing protein"
                     /protein_id="HIR1097141.1"
                     /translation="MDLTYLKTLLGFVSNRTHDTTTSILAYWEVLEYFQELSFPQASK
                     SGLPEDEVRVRYVRSEDELKYFIYAPYRDADSFRLYVGGVPKYDLLSELYRLIPADKD
                     NERFRKLLEKNKSVSVLYTIDLSPSGEYIEGSFQLSPYIWAISCLIHDREVDEEWLEE
                     LLEDGNDFFMTIEDEEGIEFFSLLRQKTVELLDRLRIRSLFTVNDGFRRNDLERVCAR
                     ALKSDDTDLSISFYAKDLSRVRKSLLDKRPNRLLVNYINAPLMSGGNRQSICSIENYR
                     KWLGPERYPLGRWPSEFSPALMQQMAINIALAEENAGGCGIFSVNGPPGTGKTTLLKD
                     IIAEYVVRRARLLADLNQPDDAFTETPLLVKSLEAGKSQKTFGLQTGRGLADYGILVT
                     SCNNTAVENITFELPETSKLPTAEAMSKAGHSLVFSEGKDLFFGDLASNMLNGNTDPG
                     KHTKQAWGLISARLGKGDNIRSFSEMVLRPFVSKMSPKRDNEKVMREFKNRFPSFDIA
                     QQEFLKQYRIVERLRRSVSCNEEVFRMADEKMQSSNPLKNAEFDKAREDLFYQALVLH
                     GSFVINSYKWRCNLYSLLAFWDNKYMPEEKELIFSHVLNSLFFLVPVVSTTFASVQKM
                     LEYMGREQLGLLIVDEAGQAAPQCAVGALWRAKKAIIVGDPKQVEPVVTTDETLMTLY
                     QKKCGIVSLSSYLSKSHSVQGFADLINRYGSWIGETWVGCPLVVHRRCINPMFSISNR
                     VSYDDTMILGMKDAVKDEEKSQLLLDHSLWIDVPGKKGTSAKGNNDHYVAEQGEVCLR
                     LILAWMGKHREKEDTRKLYVISPFTTVVKGIKAAVKAVLNTEEYSGLKGKFKGWETAN
                     CGTVHKFQGKEAEEVIFLLGCQPSSTGAIGWVNSNILNVAVTRAKKRVYFIGDYEVWS
                     RQNRNFSPEIICFSEEDTGLQRIHFSELPDFGEIEAMEETPDLEFPGAEDSQVEYLLE
                     EDEIDPETTEPEDRKQDIRPIPRYSFLTGPEYHHRYRVIYSHPYQLIFEVLMTDPTET
                     LPDLPVSFYRKLSDSPSLWMCLIYPVALDFPAQELENEFDQVIDWYNSL"
     gene            21608..22627
                     /locus_tag="ACZPB4_02575"
     CDS             21608..22627
                     /locus_tag="ACZPB4_02575"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HIR1097142.1"
                     /translation="MENLNWSELGFGYIKTDYNVRCYYRDGKWGELEVSSSEIINIHM
                     AATCLHYGQESFEGLKAFRGKDGKIRVFRMDENAKRMQSSSRGIKMAELPVEMFEEAV
                     RKVVKLNERFVPPYESGAALYIRPLMIGLGAQVGVKPAPEYMFMIFVTPVGPYFKGGF
                     QPSKVCVLREYDRAAPNGTGTIKVGGNYAASLVAGEIAHSKGYAAVLYLDPKEKKYLD
                     ECGPANFFGIRGNSYITPQSHSILPSITNKSLQQLAEDMGLTVERRPVPFEEIATFDE
                     AAECGTAAVIAPISQIDDLDENKSFVIAKDGKPGPVCEKLYHKLRAIQYGDEPDTYGW
                     ISIIE"
     gene            22808..23986
                     /locus_tag="ACZPB4_02580"
     CDS             22808..23986
                     /locus_tag="ACZPB4_02580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005643832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HIR1097143.1"
                     /translation="MEAFFKTHKYLVEHLYSPVRRGLMDEINWEDRLIGIKGSRGVGK
                     TTFLLDYAREYFGADNKECLYINLNHFYFTERTLVDFAAEFRAKGGKVLLIDQVFKYS
                     NWSRELRYCYDNFEDLKIVFSGSSVMRLKEENPDLSGKVVSYNLRGFSFREFLNLMSG
                     NQFSAYTFDEVVENHQEIAKRICSVVRPMAYFQDYLHHGFYPFFLEKRNFSENLLKTM
                     NMMLEVDVLYIKQIEQSYLPKLRKLLYLLATSAPCTPNVSQLSKDIETSRATVMNYIK
                     YLTDARLMNMLYPVGESFPKKPSKVYMYNSNLMYPIRPMEVNAGAVRESFFYNQLLKD
                     NKLNEGIKNAHFLVNTMYNFRIEENMKVKNNPDMYYAVDKTEIGEGNMIPLWLFGFLY
                     "
     gene            24025..27576
                     /gene="nifJ"
                     /locus_tag="ACZPB4_02585"
     CDS             24025..27576
                     /gene="nifJ"
                     /locus_tag="ACZPB4_02585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016903 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HIR1097144.1"
                     /translation="MTKQKKFLTCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDE
                     WAAAGRKNIFGETVMVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKI
                     AGELLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHL
                     ATIKSRVPFVNFFDGFRTSHEIQKIEALENEDLAPLIDQKALAEFRARALNPERPVAR
                     GMAENPDHFFQHRESSNTYYEAVPAIVEEYMNEVSKITGRKYGLFDYYGAEDAERVII
                     AMGSVTEAAREAIDHLIAKGEKVGLVSVHLYRPFSAKHFLAAVPKTAKRIAVLDRTKE
                     PGANGEPLYLDVKDCFYGQEDAPVIVGGRYGLGSKDTTPAQILSVFENLALPMPKNQF
                     TIGIVDDVTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKYC
                     QAYFSYDSKKSGGFTCSHLRFGDHPIRSTYLVNTPNFVACHVQAYLRMYDVTRGLREN
                     GTFLLNTVWGAEELAKHLPNKVKRYFAQKNITVYYINATQIALEIGLGNRTNTILQSA
                     FFRITGVIPVDLAIEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYNQLTVDPAWANL
                     PDDEAVVNNDPAFINEVVRPINAQDGDLLKVSAFKGIEDGTWAQGTAKYEKRGVAAFV
                     PVWNEANCIQCNQCAYVCPHASIRPFVLNDEEQKGASFAMLDVKAPAAMKGMKFRMQV
                     DVLDCLGCGNCADICPGFKGNKALSMVPLEGQLAEADNWNYCVTNVSSKQNLVDIKSN
                     VKNSQFATPLFEFSGACSGCGETPYVKLITQLFGDREMVANATGCSSIYSGSVPSTPY
                     TTNEKGQGPAWANSLFEDFCEFGLGMELANEKMRARLEGLLQQITVGEHAPAEAKEIA
                     AAWIANQNDAEKTKELAPQIMAFVEQGIKEGCPVCAQIKELSHFLVKRSQWIIGGDGA
                     SYDIGYGGLDHVIASGKNVNILVLDTEVYSNTGGQSSKATPVGAIAKFAASGKRVRKK
                     DLGLMATTYGYVYVAQIAMGADQAQTLKAIREAEAYDGPSLIIAYAPCINHGLKKGMG
                     KSQAEEKEAVACGYWHLWRYNPALEAEGKNPFTLDSKEPDWSKFQDFLKGEVRFASVA
                     KQYPAEAAELFAAAEENAKWRLRSYKRMAAENWDVEA"
     gene            complement(27883..29052)
                     /locus_tag="ACZPB4_02590"
     CDS             complement(27883..29052)
                     /locus_tag="ACZPB4_02590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin"
                     /protein_id="HIR1097145.1"
                     /translation="MRKHFLLFLLCLATNASLTAQETLRENNGEPTLVERLSNGEIKI
                     NSAEMNFQLFTSANAEFVGNELDGMNFKLNRVRLEIKGDVGKWLGYHYRQSFNKYSDP
                     YSLDNLSSSLELAYVNLKARHNLNFTIGKQFVNFGGYEYYVNSIRVREFSEFNNLLTA
                     YQAGISGNWQVSPDHELCFQIVNNRNGNDEDIYPTGLPEGTAKAKIPFMYTVNWNSYY
                     LDKTLQLRYATAVGQQTRKRYSYYFTCGNTYEKGPLLTYLDVMYTRQGIDQHGVVSRL
                     PGTPHTAMNTEYLSIIGDVDYRVHPQWNVYVKGAYETAWVYKSNGDFRKGMYRRSWNA
                     QSSVEFFPFKQLDLFVFVLYTYRGVILEKAATRMGAIEPDTHRISLGLVYSIPVF"
     gene            complement(29200..30234)
                     /locus_tag="ACZPB4_02595"
     CDS             complement(29200..30234)
                     /locus_tag="ACZPB4_02595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HIR1097146.1"
                     /translation="MEYRQLGGSGLYVPALCLGTATFGGTNGFEGWGHTKVEEATRMV
                     NLCLDAGVNLFDTADVYSNGLSEEILGKAIHGLRNRLLISTKATFNLSPESRNAIGSS
                     RFHLIQACEASLRRLNTDHIDIYHMHGFDANTPVEETLRALDDLVTSGKVRYIACSNF
                     SGWHLMKSLSVSERYGWSRYVAQQVYYSLLNREFEWELMPLGIDQKVGAIIWSPLSAG
                     RLGGKYRRNNPIPTDGRVARGGSPIPDEATSYERLYDIVEVLEQVAEETGHSVAQCAL
                     NWLLQRPTVSSLIIGARTEEQLRQNLEAIGWSLSPEQVKRLDMASQTTPIYPYWHQAQ
                     FPELNSQLRF"
     gene            30331..31107
                     /locus_tag="ACZPB4_02600"
     CDS             30331..31107
                     /locus_tag="ACZPB4_02600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HIR1097147.1"
                     /translation="MIKAVFFDIDGTLVSFKTHKLPDSTVRALDLLREKGIKVFIATG
                     RQLQSINNLGTQEFDGYVTLNGGYCLAGKDKVIYKHNIPAGDIEALIRYQENEEAFPC
                     ALVEEDGIYQNYVDDSVRQLYDMLDFPHPPLRPLRGNGGKEVYQLIAFFSPGHEERIM
                     SVLPHCEATRWNPLFADVVPRGSSKAVGIDKIIEYYGISLHETMAFGDGGNDMAMLCH
                     AGIGVAMGNAGDEVKEAADYVTDSVDDDGVMNALRHFDVI"
     gene            31142..31684
                     /locus_tag="ACZPB4_02605"
     CDS             31142..31684
                     /locus_tag="ACZPB4_02605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004089 - carbonate dehydratase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-class carbonic anhydrase"
                     /protein_id="HIR1097148.1"
                     /translation="MIDELVSYNREFVKNKGYEKYITNKYPDKKIAIVSCMDTRLTEL
                     LPASLGIKNGDVKIIKNAGAIISHPFGSVIRSLMVAIYELGVVEVMIIGHTDCGAKHM
                     NSSEMIEKMKERGIPQERIDMIRYCGINFESWLRGFETSEASVHETVEQIRNHPLIPS
                     DITVRGFVIDSVTGELTPVE"
     gene            31871..32032
                     /locus_tag="ACZPB4_02610"
     CDS             31871..32032
                     /locus_tag="ACZPB4_02610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097149.1"
                     /translation="MMMRENEKSLRALAMLRYQADRYQSAGNGAMSQRLNAEIRRLMS
                     EMSVDADKN"
     gene            32266..33270
                     /locus_tag="ACZPB4_02615"
     CDS             32266..33270
                     /locus_tag="ACZPB4_02615"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005775424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008235 - metalloexopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M28 family metallopeptidase"
                     /protein_id="HIR1097150.1"
                     /translation="MKKAGLLLMSLALSTALWAESPEKKGLDVINRSTAEAHIGFLAD
                     DDLEGREAGFRGGRIAGDYIVANLKSLGIDPVGDSYYHPFEAYHLERQKRGARWQVHP
                     DSVAAIKQTGVFQKLSLNNILGKIEGKNPNEIVIVGAHYDHLGIDPMLDGDQIYNGAD
                     DNASGVSAVLQIARAFLATGQQPERTVIFAFWDGEEKGLLGSKAFVQSFPEIKNVKGY
                     LNFDMIGRNNNEAKPTHVVYFYTEAHPAFGDWLKNDIKKYNLNLAPDYRPWDNPVGGS
                     DNGSFAKIGIPIIWYHTDGHPDYHQPSDHADRINWDKVVNITKASFLNMWYMANEKDF
                     "
     gene            33796..36942
                     /locus_tag="ACZPB4_02620"
     CDS             33796..36942
                     /locus_tag="ACZPB4_02620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SusC/RagA family TonB-linked outer membrane
                     protein"
                     /protein_id="HIR1097151.1"
                     /translation="MLKNFKPVSLILCAGALCFSGSMYANIAPVEQGTSISQQNGKVT
                     GTVEDDFGPVTGASVVVKGTTNGTITDMDGNFTLEGVKNGDVIQISFIGYSTMEITYT
                     GQPVGVIKLAEDTQKLDEVVVTALGMKRSEKSLGYAMQELKGDALLDSRESNIANALS
                     GKVSGLQVVRSSGSVGGSSKIVLRGANSLTGSNQPLVVVDGTPMDNFTGGVDDAWGNS
                     GTDMGNGLSDINPEDIESMSVLKGASAAALYGSRAGNGVILITTKSGKKNDGLGINVN
                     FGVTADTPFMLPELQSSFGQGSVGAYNDQTNLSWGPRIEGQTITTYDGRQVPMAAYDN
                     IGAFFGTGTSFNEGVSFQQDVNGTSMFFSFNRQDDSGVTPEQSLNKTNLTLRATSFLD
                     EAKKWKVDAKVNYVNQNAHNRPIIGINPSNAFSTVYNLPRSLNVLDFENCVDDQGKMV
                     WYDKSNSPQENPYWVTQYRQNDDTRNRILGNASLKYAPTDWFDIELRGGTDYYTTTTT
                     QKLYSGGNTKPEGSYSEGSETFYENNFSFLATARKDDLISKLGGFVTFGGNIMQQKRT
                     KMNASAGTLLVPDLFDVNNGVDKPSITSSLTQRKMNSLYGSLQLNWDGWLFLDVTARN
                     DWSSTMSKENRSYFYPSVSLSAVISDMVQKNGGSMPDWFSFAKVRASFAEVGNDLDPY
                     QLYNVYTISKDANGNSMASAGSTLFDSSVKSELIKSWEVGADLRFFNNRFGIDAAWYK
                     TNATNQLLNIPMDAFSGYESRKVNAGNIQNQGFELSLNGAIMQTASGFNWDAQAHFSL
                     NRSKILELTEGVTVYDIKTVDVLQIAATEGGKYGDIYGQKFVRHNGQVVVGEDGLPLI
                     TTDKELIGNQNPDWMLGLTNNFSYKGFDLSFLIDFRIGGEIYSATTSSLHKNGNAAGT
                     VVNGDRADFVVPNSIMKKGDEYVKNDVAVTPQRYWERIASSGNYGLPEVFTYDATNIR
                     LRNITLGYTFNKNLLKKTPFQKLRLSATCNNVWMIVSHLPGIDPESVAATNTNAVGFE
                     NGGAPTNRSYTFNLTVGF"
     gene            36958..38913
                     /locus_tag="ACZPB4_02625"
     CDS             36958..38913
                     /locus_tag="ACZPB4_02625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SusD/RagB family nutrient-binding outer membrane
                     lipoprotein"
                     /protein_id="HIR1097152.1"
                     /translation="MKTKNIIILGALAVASLTTVTSCNDFEDINKDPNKADLEQVEPE
                     WFLNGSIGDAQMNPEIAERIFILYWKRAARFDRGSGFAIGTDNDDYNRLYLTSNSYGV
                     GWLNKANQAIEVGEEKIKLDVDNAYPYYRNIPNMARIWRAYLNSELSDNFGPIPALSA
                     FTGVPGEYNKVEDIYTYILKELKEAVASLDESIDMSAMSKYDPFFGGDIKKWKKYGNS
                     LRMRLAMRLTAVNPSLAQAEFEDAAKGEFIASMDDIAQVAEKDGWDPYTGVMTRTWNN
                     QAMSTTFNNLVVGLGGVEFPVPDELKSNLKDPYTYLGQNVSLHFPTTTNDPCAGYFFD
                     GIPQYIDPRAPQLYSIPGYDDGVVYPSYIGAASEVKDEITLIAGDYTDVLTGQKVSAP
                     EVKLPMKYSWTTVVAGNWNDKAGLVGDYTSYNYNFPSLADKFRHSTNKRVWFGPWESY
                     FLLAEAAVYGWNVPGSAKDNYEKGIAASFEYNGVSDKLLEYLQSKAYNRVGTSVAFDH
                     TVEAKAYTINYYDAYTKQNKTTTYEYPKNTIYKNGQYNNDALTKIITQKFIAQNPWLP
                     LEVWSDHRRLGLPFFENQAVEAAYNPTNQVLLTPATCKECKVEFYPKRLRYPAVLQTN
                     NLEGYNQALERLGGPNMTTTSLWWNMK"
     gene            39023..39388
                     /locus_tag="ACZPB4_02630"
     CDS             39023..39388
                     /locus_tag="ACZPB4_02630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097153.1"
                     /translation="MRKLLMVLFLFGTISVFCNAQIDGYYVKDSGNLALFADGEPRTS
                     NSIGIEAGKSVEIRFTQPSTGDFLWQKMSGSDYIQFNPGGSGRFALIWTQSASKGDSA
                     VFCVTDKNGDVLTITIHAY"
     gene            39854..43021
                     /locus_tag="ACZPB4_02635"
     CDS             39854..43021
                     /locus_tag="ACZPB4_02635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SusC/RagA family TonB-linked outer membrane
                     protein"
                     /protein_id="HIR1097154.1"
                     /translation="MLKRFRPVSLILLVGALGFSGNLYATPMSGIPRVDISQQNAKVS
                     GIVEDALGPVTGASVIVKGTTNGTMTDLDGHFTLDNVKKGDIIQISFIGYTSQDIPYT
                     GQSEITVKLVEDTQKLDEVVVTALGMKRDKKALGYAMQELKGDDLLASREPNLANSLS
                     GKVSGLQIVRSSNGVGGSSKIVLRGNNSLTGSNQPLIVVDGTPMDNFTGGVDDVWGNS
                     GADMGNGLSDINPEDIESMTVLKGASAAALYGSRAGNGVILITTKSGRKNEGLGITIN
                     AGITAETIFLKPDLQNDFGQGSVGVYDNQSRLSWGPKAMGQMVTDWRGNQIPLHTYDN
                     IDAFFRTGTSFNEGVSFQQNIKGTAVFASVNRSDDASITPRSKLNKTNITLRATTFLD
                     EAEKWKVDAKVNYINQNAHNRPIQGVNPSNAFNTIYNLPRSLNIREFEDDVDEQGNMI
                     WYDASKNPQENPYWVTRYRQNEDTRNRLLGNISLKYAPTDWFDIELRGGTDYYTTTKS
                     EKVYAGGNTSPRGLYTEGSETFYENNFSFLATARKDNLIDRLGGFVTFGGNLMLQQRN
                     KMNASAGELLVPNLFSLNNGVNKPTVTSELIRRRMNSLYGSLQLNWDGYLFLDVTARN
                     DWSSTMSKANRSYFYPSVSLSAVISDMLPKIGGSMPDWFSFAKVRASFAEVGNDLDPY
                     QLYNFYSVGKDPNGNTTAKPGKVLYDSDVRSELIKSWEAGFDIRFFNNRLGLDAAWYK
                     SNATRQLLDLPMDPFSGYASRKINAGNIQNEGLEISLNGTILDNPAGLSWSSTAQFSL
                     NRNKIKELYEGVNLYDIKTFDAIQIVAPVGGYYGEIYGQTFMRVTDENSPHYGKIVVG
                     DDGLPLISTEKSKVGNQSPDWMMGWTNNFSYKGFNLSFLIDFRIGGSIYSATASNLYT
                     RGNAAGTVVNGDRAEFVVPNTVVQQGSGYAENTVAVTPQNYWERIGSTGNYGLPEVYT
                     YSATNVRLRNITFGYEFNRQMLKKTPFQRVRLSATCNNVWMIHYNLPGIDPESVAATN
                     TNATGFENGAAPTSRSYTFNVTVGF"
     gene            43063..44982
                     /locus_tag="ACZPB4_02640"
     CDS             43063..44982
                     /locus_tag="ACZPB4_02640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SusD/RagB family nutrient-binding outer membrane
                     lipoprotein"
                     /protein_id="HIR1097155.1"
                     /translation="MKTRNILFTGLVSVAALLSSCNDFQEINEDPNLVGEDKVKPQWF
                     LNASIMGDQMNPEIAERIFILYWDRASRFNRGSGFTIGTDNNDYSTIYLSNDYAVGWL
                     NQVTKAIQLGEQMVANGEADTYPYYKNVIQMSRIWRAYLNSEVADGFGPIPALAAFSG
                     VPAEYDSVEAIYQFILKELREAESALDPSLDMSAMANEDAFYAGNVTKWKKYANSLRM
                     RLAMRISAVDPALARAEFEDAASKTFISEPTDIASVQEKEGWDELTSVMSRPWNGQAM
                     SVTFKNLVVGLGGQEFPLPDSLKSHLKNPYDYQGLYLNQHFPLTTNDPCAGFYFDGIP
                     QYVDPRAPKLFSVVGWDDGVVYSDYIGAASEVKPVHLKNPADNTQNMLMIDPKYTWGT
                     WVAGEWDVKAGLVSELTGKNYNYPSISKQYRMSTNKRVFFGPWESYFLLAEAAVKGWK
                     VPGTAKSNYESGVTASFEYHGLLSQVGDYLSSQKYNRVGTSVAFDHTTEAKSYTIRYT
                     DPYTKEVKSRTYEYPHNSIYRNGAYNNDALTKIITQKYIAQVPWLPEEAWSDHRRLGL
                     PFFENQAVEKDYNPLNQVPLTVATSKECRWDFYPKRYRYPANIQTNNQAGYAQALQLL
                     GGPDLTTTPLWWNAK"
     gene            complement(45059..45865)
                     /locus_tag="ACZPB4_02645"
     CDS             complement(45059..45865)
                     /locus_tag="ACZPB4_02645"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HIR1097156.1"
                     /translation="METIQQKNRIILLWPDGAPTSNGLAGVELEDAPNAISNISNPSL
                     LVYPATKPNGKAILMCPGGGLSKISIGHEGRDMAAWFNAQGITYAVLKYRMPNGHREV
                     PLDDVRQGLRILHNYSEEWKITKVGVMGASIGGYIAGHAAIFGVDDARPDFQILLYPV
                     ISMLPHLTHLKSRERLLGANPTHEEEEAFSLELHVNSLTPPAFIALASDDEAVSPENS
                     VLYYLALLKNKVSASLHIYPKGGHSFGFRDNFVYKRQWTDELEKWLSTIE"
     gene            complement(46034..46915)
                     /gene="fabD"
                     /locus_tag="ACZPB4_02650"
     CDS             complement(46034..46915)
                     /gene="fabD"
                     /locus_tag="ACZPB4_02650"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010799941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HIR1097157.1"
                     /translation="MKAYVFPGQGAQFVGMGKDLYDNNPLAKEMFEKANEILGFRITD
                     LMFAGTDEDLRQTKVTQPAIFLHSVILAKTLGDQFQPDMTAGHSLGEFSALVAAGALS
                     FEDGLVLVSKRAMAMQKACEATPSTMAAVLALPDATVEEICASIKDEVVVCANYNCPG
                     QLVISGSIPGIDQACEKLLAAGAKRALKLKVGGAFHSPLMEPARTELAAAIEATTINK
                     PSCPVYQNVSTKAETCPETIKTNLIAQLTAPVRWTQSVQNMIADGATHFIELGPGAVL
                     QGLVKKINKEMTTEGMQ"
     gene            47055..47249
                     /locus_tag="ACZPB4_02655"
     CDS             47055..47249
                     /locus_tag="ACZPB4_02655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0033281 - TAT protein transport complex
                     [Evidence IEA];
                     GO_function: GO:0008320 - protein transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0043953 - protein transport by the Tat
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Sec-independent protein translocase subunit
                     TatA/TatB"
                     /protein_id="HIR1097158.1"
                     /translation="MNELLFLGNLGTGEIVIIAIVVLLLFGGKKIPELMKGIGKGVKN
                     FKDGVKGLEDDIKLDDTEKK"
     gene            47256..48083
                     /gene="tatC"
                     /locus_tag="ACZPB4_02660"
     CDS             47256..48083
                     /gene="tatC"
                     /locus_tag="ACZPB4_02660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0015628 - protein secretion by the type II
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="twin-arginine translocase subunit TatC"
                     /protein_id="HIR1097159.1"
                     /translation="MQQEEMSFWDHLEELRWTLFRSILALFVFAIAGFSVMPWLFDNV
                     VMAPCSSDFIVYREMCKISSHFSFLPDFCNDTFHVNIVNIKLASQFFTHMTSSFWLAL
                     LLTFPYLMWEIWKFVSPALYENEKKNVRWVFLFGTIMFFIGCSVGYFLVFPMTLRFLA
                     TYELSAAITEQVSLDSYMDNFLMLIFVMGIVFEMPLVSWLLSQIGLLNRSFFHKYRRH
                     AVVGLLVGAAFITPSSDPFTLSIVFLPLYGLYELSAFFVKKAPKEEDEENEEDNNEE"
     gene            complement(48152..49024)
                     /locus_tag="ACZPB4_02665"
     CDS             complement(48152..49024)
                     /locus_tag="ACZPB4_02665"
                     /EC_number="3.5.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016813 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds, in linear
                     amidines [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginase family protein"
                     /protein_id="HIR1097160.1"
                     /translation="MEDKTSTLRLIYPQWQGGIVNHWMPDLPADDASRGYYLGAQLLN
                     ILAPPSPQKTVEVPISLDINDRETDLGISARKVILKQTKAALELLHENAPEKIVTLGG
                     ECSVSVVPFTYLAAKYPDDIAIVWIDAHPDINLPYDEYKGYHAMALTACLGMGDEEIL
                     QLLPGKFKVSNTLIVGLRSWDEGMKERQKNLGIKGLSPEEVAKDSSSILKWLKGTGAS
                     KVVVHFDMDVIDPADMIAGVGVEPNGMKIDEVVRVINNIASKYDLVGLTVAEPMPRIA
                     IKLRNMLDRLPLLK"
     gene            49143..51449
                     /locus_tag="ACZPB4_02670"
     CDS             49143..51449
                     /locus_tag="ACZPB4_02670"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HIR1097161.1"
                     /translation="MKIESFPRKLFLFRNNLCMFAQTQNELHNMKHMSILAVSLLALV
                     ACTPEKKQEADYSQYVNPMIGTDFTGNTYPGAQVPFGMVQLSPDNGLPGWDRISGYFY
                     PDTTIAGFSHTHLSGTGAGDLYDISFMPVTRPYKEAPAPLGIYSTFSHNDEAASAGYY
                     RVLLKDYNINVELTATERCGIQRYTFPEAEASVFLNLKKAMNWDFTLDSKIEVVDSTT
                     IRGYRLSQGWSPLQHVYFETRFSKPFVACHMDTTSIVTKEKGWIGTAYVARFDFNTKK
                     DEEILVTTGISGVSMEGAGKNLRAEAPKDDFDYYQAQASANWNRQLSKIEVKSRNTDD
                     MVKFYTALYHSMIAPTIYSDVDGSYYGPDQQIHKADGWTNYSTFSLWDTYRASHPLFT
                     YTEPERANDMIKGFLKFYEQNGALPLWNLYGWETNMMIGYHAVPVIVDAYLKGIGDFN
                     AEKALEACIATANRDDYRGIGDYKKLGYVPAYSDPKKWENWSLSKTLEYAYDDYCIAK
                     MAEKMGKKEIADEFFKRSQNYHNVYNPATSFMQPRDEKGNFAANFSPDDYTEDICESN
                     GWQYFWSVPQDLDGLIGLVGSKERFAEKLDSMFTYVPKSDEELPIFSTGMIGQYAHGN
                     EPSHHVIYLYNKVGQPWKTQKYVAQVLHDLYLNAPDGICGNEDCGQMSAWFVFSAMGF
                     YPVDPISGQYEIGSPLFPEVKMHVGNGKTFTVLAPEVSAENIYIQSVKLNGQPYDKSY
                     ITHEQIMSGATLEFVMGSQPGPVWYTNE"
     gene            complement(51510..51644)
                     /locus_tag="ACZPB4_02675"
     CDS             complement(51510..51644)
                     /locus_tag="ACZPB4_02675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097162.1"
                     /translation="MEEYIDSIIRVGKILIGSMMVVFVLWYIVKDIVKAYGKDSHEPD
                     "
     gene            51778..52776
                     /locus_tag="ACZPB4_02680"
     CDS             51778..52776
                     /locus_tag="ACZPB4_02680"
                     /EC_number="3.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004067 - asparaginase activity [Evidence
                     IEA];
                     GO_function: GO:0008798 - beta-aspartyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoaspartyl peptidase/L-asparaginase family
                     protein"
                     /protein_id="HIR1097163.1"
                     /translation="MLKQMIALTALMVSSIAFAQDREYVIVVHGGAGAMAGLEEDPVK
                     SAQYYAALDSALMIGDKVLSAGGEGPEAVMAVINYFEGNPLFNAGIGATCTAEGTFEL
                     DASIMEGKDLSAGAVAGLKHVKHPINAAYAVKTKSPHVMLSGAGAEEFAKEQGLEMVE
                     DNMYFATPKTMEWIEKLKQESKKNGTVGCVVLDKQGNLTAGTSTGGMFKKRWGRIGDS
                     PVIGAGTYADNNSCAVSCTGHGEYFIRHAVAFDVCARYKYLKESVEKAADYIIHTELN
                     TNAGNGGLIAVDKLGNIAMPYNSGGMFRGFLYKEKGRPEIKKGCGIGKKIVVVGEK"
     gene            52810..54180
                     /gene="radA"
                     /locus_tag="ACZPB4_02685"
     CDS             52810..54180
                     /gene="radA"
                     /locus_tag="ACZPB4_02685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HIR1097164.1"
                     /translation="MAKTKTVYVCSNCGADSPKWLGKCPNCGEWNTYVEEIVTKELAV
                     KRPVPGIMEGNKIRPVLLRDITTEEEARIDLKDDELNRVLGGGLVKGSLVLIGGEPGI
                     GKSTLVLQTVLGLTGLKTLYVSGEESSRQLKLRADRLSHDNPNCFILCETHLEQIFTQ
                     AANIQPDLMIIDSIQTIFTEVVESSPGSVSQVRECSAAILKYAKESGVPVLLIGHINK
                     EGSIAGPKVLEHIVDTVLQFEGDQHYMYRILRSIKNRFGSTAELGIYEMRQNGLREVS
                     NPSELLLTQNHEGLSGVAIAAAIEGVRPFLIETQALVSSAVYGTPQRSATGFDLRRMN
                     MLLAVLEKRAGFKLIQKDVFLNIAGGLKVNDPAIDLAVISSILSSSLDISIEPGVCMA
                     GEVGLSGEIRPVNRIEQRILEAEKLGFSRIIIPHNNLKGFDTAKSKIQIVQVKKVEEA
                     FRQLFG"
     gene            54194..55798
                     /locus_tag="ACZPB4_02690"
     CDS             54194..55798
                     /locus_tag="ACZPB4_02690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HIR1097165.1"
                     /translation="MIKELQLRILPEEAVNEQSLRQVVARETGEAPKNIRAVRVLKRS
                     IDARQRTIFVNVKLRVFMNEMPSEPEYQSIEYKDVSAGKPVIVVGAGPGGLFAALRLI
                     ELGLRPIIVERGKDVRERKKDIALISREHKVNGESNYSFGEGGAGAYSDGKLYTRSKK
                     RGSVDKILNIFCQFGASPSILADAHPHIGTDKLPRVIENIREQIKRCGGEVHFETRMD
                     AFIMKENEVIGIETNTGKSFYGPVILATGHSARDVYNYLYERQIQIEAKGIAVGVRLE
                     HPQELIDQIQYHRKEGRGKYLPAAEYSFVTQANNRGVYSFCMCPGGFVVPAASGPKQV
                     VVNGMSPSNRGSRWSNSGMVVEIRPEDYSELVGQEELYLRNGEKVDADSPLALMAFQE
                     RLEEVCWLNGGMKQTAPAQRMDDFMRKKNSFDLPVSSYTPGLLASPLHFWMPEFVTSR
                     LREGFRYFGKVSRGFLTNEATMIGVETRTSAPVRILRDRDTYQHVTVKGLFPCGEGAG
                     YAGGIVSAAIDGERCAEGVYNLESNK"
     gene            55816..56937
                     /locus_tag="ACZPB4_02695"
     CDS             55816..56937
                     /locus_tag="ACZPB4_02695"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HIR1097166.1"
                     /translation="MKIGISLCLGVLMCLNAGCTGKKSAVEEPELTYSNPLSVQFGDP
                     YVLLASDGRYYMYGTGAGAVDGFCAYSSDDLIHWKSEGQVYRGNTPDSWAIANFWAPE
                     VYERDGKFYMFFSADWRKNPTNEEENFRIGVAVSDKPTGPFKELADAPLFDPGYPVID
                     GNLIEDEEGRTYLYYSRCCYKHPVESEIADEAKKKGMFDSVEESWIYGVEVAQDLTHV
                     IGEPVLLLRPPVKLDDAQSEWESRSVTKGEVGRRWTEGSFMLRHNGLYYMMYSANYFG
                     GANYAVGYAVSEHPLGPFEKASNNPVLEKNVEKGGIVTGTGHNSVTWSKDGKQMYCVY
                     HGRTQKTGDERVVFIDKMRIDENGLLVVEGPTTDPQSIQ"
     gene            complement(56931..57320)
                     /locus_tag="ACZPB4_02700"
     CDS             complement(56931..57320)
                     /locus_tag="ACZPB4_02700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097167.1"
                     /translation="MLKRDFIMVQIEELGKVIAQIIFNRNSNDGARKNPELIQSVYTS
                     LKLDNDFLLNTPIDGIRTYLDGDDSCGLQRMELATKTLLEESFLLPEAQGKKLRARAK
                     ELLEYIQRNDTTFSLERVALLEEINNY"
     gene            complement(57333..58142)
                     /locus_tag="ACZPB4_02705"
     CDS             complement(57333..58142)
                     /locus_tag="ACZPB4_02705"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HIR1097168.1"
                     /translation="MKKIYYILSALFLCVVATSAQEAGKTVVIKTNVGTMKAILYDDV
                     PNHTRTFIERAKRGDFNGTLFTRVLPEFMIQGGAPDSKNAPAGAKCGFGDPSAEILPE
                     INEKYFHKKGALAAPRQPDDVNPQKKSDMSQFFIVQGKVYRETELDTLERTANYPARQ
                     KALKEFYAPVRAELNMIKMSNKREYQKRLRMINAQIDSVIQATPGHLLFTDEQRKAYT
                     TVGGCHHLDGTYTIFGELTEGFDVLDQIATQPKDQNDRPKKDIRIQSITIE"
     gene            58251..59927
                     /locus_tag="ACZPB4_02710"
     CDS             58251..59927
                     /locus_tag="ACZPB4_02710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005640306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative transporter"
                     /protein_id="HIR1097169.1"
                     /translation="MDWINDLLWGEGIGHSILLLSFVIAAGIQLGKIKVFGISLGITL
                     VLFVGIILGHFGFTVNHNVIHFFKEFGLILFVYSVGMQVGPGFFSSFRQGGITLNMLA
                     CGIVFLGVATALVLHFVTGIPMPTMVGILSGAVTNTPGLGAAQQAYSDMYGVSDNTIA
                     LGYAVAYPLGVIGIILSIIFVRYVFRVNFDKENDDLNKEDASHTNEAKPISLVVKNPA
                     VFGKTVGELSGLMDHLDFVISRVWRNDNKQIEIASAGTILNEDDKIFVITTDQDAESV
                     KTFIGEEIDMERKQWIRMESQFINRRILITKPELNGKKLGQLKLRKLYGINITRINRA
                     GVDLVATPGLTLQVGDRVNVVGTETAVSNVEKVLGNSMKRLNEPNLITIFIGIALGIV
                     LGSIPITFPGIPQPVKLGLAGGPLIVAILISRFGYRYKLVTYTTQSANLMLREIGITL
                     FLACVGISAGDGFVDTIVNNGGFAWIGYGFIITTVPLLIIGCVGRYFYKINYFTLMGL
                     IAGSTTDPPALAYSNATAGNDAPSVGYATVYPLTMFLRVLTAQLLILFFA"
     gene            60172..61023
                     /locus_tag="ACZPB4_02715"
     CDS             60172..61023
                     /locus_tag="ACZPB4_02715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HIR1097170.1"
                     /translation="MSVEKKNAYIGVDLGGTNMRAGRIAGDRLVAQGNAPTPQDAADC
                     GETLEALIEVIRSVWDEGVVAIGIGVPSVVDREKGIVYNVVNIPHWEEVHLKEILEAR
                     FSVPVYVDNDANCFALGERIFGDGKTVDNFVGLTLGTGLGGGVIQKGKLLADANCGSG
                     EFGMIPYQGQILEYFCSGSYFMNVWGVDGKEMYTRAMRKDEQALEAYRQLGVHVAAAI
                     KIVVLTVDPEMIVFGGSVTAAHELFEESMYEDLKDFAYPNSIKNLKIRFSKLENPGLF
                     GAASLCY"
     gene            61068..61979
                     /locus_tag="ACZPB4_02720"
     CDS             61068..61979
                     /locus_tag="ACZPB4_02720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ThuA domain-containing protein"
                     /protein_id="HIR1097171.1"
                     /translation="MRHVFCRKIVFLLAALLVVCGMSARKPIKTLLITGQNNHNWQVS
                     HVVLKQILENSGRFSVDFAVSPEAGKDMSGFVLDFSPYELVVLDYNGDAWPEETNRRF
                     LEYVRGGGGVVVYHAADNAFVNWPEYNKICALGGWENRDEKAGPYVYWSDGKLIKDSS
                     AGVGGSHGKQHEYVLNARNHDHPIMKGLPNKWKHAQDELYDRMRGPGNIKDCLYTAYS
                     DKETGGSGREEPLIFTVDYGNARIFHTMLGHAGETVENCPAMQCAGFQITLLRGAEWA
                     ATGKVTQKVPTDFPTEKQVSNRSNYKR"
     gene            complement(62077..63993)
                     /locus_tag="ACZPB4_02725"
     CDS             complement(62077..63993)
                     /locus_tag="ACZPB4_02725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010185069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0043138 - 3'-5' DNA helicase activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RecQ family ATP-dependent DNA helicase"
                     /protein_id="HIR1097172.1"
                     /translation="MDVYHKILEKYWGYPAFRPLQEDIIHSVCAGKDTLGLMPTGGGK
                     SITFQVPALAMEGICIVVTPLIALMKDQVENLRRVGIKATAVYSGMSRQEIITQLENC
                     IFGGYKFLYVSPERLSTDIFRVKMEAMQVCLLVIDESHCISQWGYDFRPSYLNIAEIR
                     DLLPGVPVLALTATATPEVVNDIQERLRFKEKNVFQKSFARKNLAYIVRKTEDKLNTL
                     VYILGKVPGTAIVYVRNRKRTKEIALMLQQAGISADFFHAGLNRDEKELRQARWKNNE
                     CRVIVSTNAFGMGIDKPDVRLVVHMDMPGSLEEYYQEAGRGGRDEKKAFAVALCSSTD
                     SAKLKKRLADEFPDKEFIYRVYEALGNYYQIAVGYGLDTVHDFSLTDFCSAYKFSLLQ
                     AHHALKILGLSGYIEYTEEVDNASRLMFTATRDELYRYLSENKRTDEVIQTILRSYTG
                     LFADYVYIDESVIATRARVTPHEVYETLVGLSRYRIVNYIPHKKTPLIIYTQTREEQR
                     YLSIPRSAYEERKERFGKRIEKVLEYINEERVCRSRMLLSYFGEEDSAPCGCCDVCLS
                     KHESQLMNWEFSAIRESLVKVLAGESPIPVKELIEKLPFPQEKSLTAIRFLADQDPRF
                     TLSDGYLSHEDSAK"
     gene            complement(64003..65727)
                     /gene="recJ"
                     /locus_tag="ACZPB4_02730"
     CDS             complement(64003..65727)
                     /gene="recJ"
                     /locus_tag="ACZPB4_02730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008409 - 5'-3' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HIR1097173.1"
                     /translation="MINKWNFQTPSEEELHKRDQLVAELGFSPVICLLLVQRGITSIE
                     EAKKFFKPSLNDLHDPFLMPDMDKAVRRLNKALGNKEKILIYGDYDVDGTTAVSLVFK
                     YLRPYSSTLDFYIPDRYDEGYGISYKGIDYAAENGVSLVISLDCGIKAIEKIEYAKEK
                     GIDFIICDHHMPDATLPDAVAVLDAKRSDSIYPYEHLSGCGVGFKFMQAFAKSNNFPF
                     SDLEKLLELTAVSIASDIVPITGENRILAYYGLKQLNSNPSLGLKGIIDICGLTGKEI
                     TISDIVFKIGPRINASGRMMNGKEAVELLLSKDSASAREKSESINQYNEERRELDKKI
                     TDEANAVIDEVENMDDRKAIVVYNPGWHKGVIGIVASRLTEKYYRPAVVLTKSSELIT
                     GSARSVTGFDIYKAIESCRDLLENFGGHTYAAGLSLREENLEAFTERFLKIASEEIIP
                     EQMIPQIDIDAILDLKEINQKFVNDLKKMSPFGPDNQKPVFCSLGVKDYGTSKLVGKE
                     LEHLKLELIDGNSSTPMHAIAFGMHRYNDHIKGMKPFNICYTVEENTYNGNTSIQLMI
                     KDIKPDDI"
     gene            65951..66511
                     /locus_tag="ACZPB4_02735"
     CDS             65951..66511
                     /locus_tag="ACZPB4_02735"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HIR1097174.1"
                     /translation="MTEDIKKACEVMAAGGIILYPTDTIWGIGCDATNEKAVQRVYEL
                     KRRTDNKAMLVLMDSEAKLDRYVSDVPDIAWDLISVSDKPLTIIYSSAKNLATNLLGA
                     DGSVGIRITNEEFSKKLCERFRKPLVSTSANVSGEPSPANFSEVSEVIKEGVDYIVSY
                     RQDDMSKAAPSGIIKLGAGGLVQVIR"
     gene            66514..67914
                     /locus_tag="ACZPB4_02740"
     CDS             66514..67914
                     /locus_tag="ACZPB4_02740"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HIR1097175.1"
                     /translation="MKKSVQAGKYIVSDFIASSVVWLLFNLIRYEEVAVYEGFDTVGA
                     FLLHIPSLKGQLLIPFFWFVLYWFSGYYNKPFGKSRLTELFSTLGSVSIGVVILFFAL
                     VLNDLPRSYHVYYDMFFSLWGLQFVLTYIPRLLITQAGLRKIKCREWALNVLMIGAGK
                     KAACIADDLYGLGYNIVGFVSDGTEKKGGVAGDRVIGRLESLPVIVEEKKVDELVVAL
                     ETVDNNRLMDILYSLYCYKRPIKILADKSSSLSQVKIKAIKGVPLVDVTDNNFLPIEQ
                     NVKLFMDKTLSLIFLVLLSPLFLYIAWRVKRDSPGPVFFSQERIGYMGEPFMIYKFRT
                     MYTNAEEEGPLLSSEDDSRITPFGRVMRKYRLDELPQFWNVLKGDMSLVGPRPERKYF
                     IERIVRKAPFYYLLHNVRPGITSLGMVKYGYAGSVDEMIERLEYDILYYENMSLILDI
                     TILIYTVKTVFTGKGI"
     gene            67916..>68736
                     /locus_tag="ACZPB4_02745"
     CDS             67916..>68736
                     /locus_tag="ACZPB4_02745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005247 - voltage-gated chloride channel
                     activity [Evidence IEA];
                     GO_process: GO:0006821 - chloride transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HIR1097176.1"
                     /translation="MANEGLFYKFLLWREKRIKEKHFILIISFIVGLCTAAAAIILKQ
                     LIHFIQHLLTGNFNADGVNYLYLLYPVIGILLAGLFVKYIVRDDISHGVTKILYAISQ
                     RKSRIKPHNTWTSIVASSVTIGFGGSVGAEAPIVLTGAAIGSNLGRVFKMEQKTLMLL
                     VGCGAAGAIAGIFKAPIAGLVFVIEVLMLDLTMTSVLPLLISSVTAATMSYIFTGTEA
                     MFKFSQTEAFEIERIPYVLLLGVFCGLVSLYFTRVMNKVEGMYRKLGTYWKKFMLG"
BASE COUNT        17160 a        15009 c        17760 g        18807 t
ORIGIN      
        1 gagaggagtc agtccgtaag gggtgactcc tttttttata ttaaatttga tgtattaaat
       61 ctattatcta atatcatgaa gaaaatctat ttatttctat ttagtctgtt tatctgtaat
      121 atccttgcgg cgcaagatca agactataaa atagtcaggg atatctctta tacccaatcg
      181 aaagatccat atgcggtgga acgttgtaaa ttggatcttt attatcccga gaacgcaaaa
      241 gacttcccta cggtagtctg gtttcacgga ggcggcttgt cgggaggtag caaattcatc
      301 ccggaggaat tgaagaactg cggattagcc gttatcgccg taaattaccg cttgctaccc
      361 aaagccacgt tgagcgattg tatcgatgat gccgccgccg ctgtcgcttg gacattcaac
      421 gagattgaga agtatggtgg ggataggcgt aaaatctttg tctcaggtca ttccgccgga
      481 ggttatttaa cgaatatggt cggactggat aagaagtggt tgactaagta tcggatagat
      541 gctgatgcca tcgccgcatt aatccctttc agcggtcatg cgatcagcca tttcgcttat
      601 cggcaggcga agggaatgaa agatacccaa ccgagtatcg acgagttcgc ccctttgttt
      661 tacgtacgtc ctgacgctcc tccattgatt atcgtctcgg gcgaccggga gatggagatg
      721 ctgggccgct atgaggagaa cgcctatttt tggcgtatga tgaaagtggc cggacataag
      781 aatacttata tctatgagtt ggacggatat gatcatggat cgatggccgc tcccgccttt
      841 cacatcttaa agaatcacgt gaggatgatc ttgaagggtt cagaaacccg gtaatttgat
      901 taactattaa tttaatacgt atggttctct tttctttatt aatggtcttg atttgcttga
      961 acgcatgttc tggagcgaag atctcggaca atgtaacggt gtatgtcacg acaaacgatc
     1021 gtgcgaaaga tttcgtgaga agtgagatcg ccttggggga caaacaagcc gcctcgcctt
     1081 gcgtgataac gatagaccct tcggtgcgct atcagacgat ggatggcttt ggtgccgccg
     1141 tgacaggctc tacctgctat aacttgatgc ggatggctcc cgaggatcgg acagctttcc
     1201 tgaaagagac tttctctgat acggagggga tggggtatag ctatatccgt atctcgattg
     1261 gctgctcgga cttttcttta agtgagtata cttgttgtga cacgaagggt gtcgagaatt
     1321 tcgccttgca gagcgaggag aaggagtatg tgataccgat cttgaaggag atcttggcga
     1381 tcagcccttc tataaaaatc ttgggatcgc cttggacttg tccaagatgg atgaaggtgg
     1441 ataacttaaa ggatttgcgc ccgttcgagt cgtggactag cggacagttg aatcccgctt
     1501 attatcaaga ttacgctacc tatttcgtga aatggataca ggcgatggag gccgagggga
     1561 ttcctatcga ggcgataact ccccaaaacg aacctttgaa ccgaggaaat tccgcttcct
     1621 tatttatggg atgggaggag caactctctt tcgtgcgtga cgctctaggc cctaaactga
     1681 aagagactgg cctcaagacg aagatctacg ctttcgacca taattacaat tacgataata
     1741 tgttggagca gcaaggctat ccgatgaaaa tctacgagga tgagaatgcc gcttctttcc
     1801 tgacaggtgc cgcttaccat aattacgggg gcgaccggga ggagttgaat aacgtaaacg
     1861 gcaagttccc cgataaagaa ttaatattta cggaaacttc tatcggcatg tggaatgatg
     1921 gacgtaactt agagaaacgc ttgatggaag atatggagga gacggccttg ggtacggtga
     1981 ataactggtg taaggcagtt atcgtatgga acttgatgct ggacaacgag cggggaccga
     2041 accgagaggg tggttgccag acttgttatg gtgccgtgga tatcgatcgc tcggattata
     2101 agacgattac ccggaattct cattattata ttatcggtca tttatcctct gtggtgaaac
     2161 cgggggcagt acggatcggc tctaaagggt atacggctga tgggattatg tattccgcct
     2221 tcgagaattt agatggaacg gaagcgctcg tattactaaa taatacggac gggactaaaa
     2281 atataacggt aaacagcggc gaacgttcgt ttacctacga ggttcccgct aaagcagtcg
     2341 cttcttttcg ttggaatctt tactaataag gagggtgtgt taaaagttgg tattatggca
     2401 cgcagattta gcagatttac gcagataata tattgatttt catatcataa atctgcggtc
     2461 atctgctcaa tcagcgttat ctgcgtgcca tgttcacact tttgacacac ccccgaatgt
     2521 ccaatacttt atctatagtg gcaacaagcc ggtagcttat catatacggc tttatccgcc
     2581 ttatccatat ccgtgtcatg gcctacttta gcgatcgcct tgctgatcgc tttcggggag
     2641 gtcttttggg gatcgtactg gagatggatc atctgggtat ctttgtccca atgagcggat
     2701 aacacaccat ttacctcttt tgccgctttc tcgatacgtt ccttgcacat atcgcaagag
     2761 cctttgacac cgaacatggc atgctcggag gctacccccg tggcgctttg cgcatgcatc
     2821 atatgcccct catgcccaat cataggcttg gcgggctcgt cgccgttatt catcatggaa
     2881 gtttttccct ccagctgtgc gctggcgtct atggcgaaga ctccgttggt tacgatttcc
     2941 tcaccttctc gcaagccatt caagataaca taagagttac caagggaagg gcctagctcc
     3001 acttcacgca tcaagaaagc gggggtattc gtatccggtt gctttacgta cacgatagca
     3061 cgtttacccg tccagagcac agcggtttgc ggtacgacga tctcgttctt atagttgcgg
     3121 agcggggcgc ttacgtttgc cgtggcgtac atctcgggct tgagctccaa agaggcgttc
     3181 ggtacctcta cacggacctt ggcggtacgg gtcgtcgtgt tcaagatcgg gtcgatgaaa
     3241 gagatcttac ccgagaactt cttgccgggt agcgcttgca aggtaaattc caccggatca
     3301 cctttgctaa ggaaagggag atccacctcg aaagcgtcga acaaggccca taccttcgtg
     3361 aggttcgcca cgtcgaaaag gatagctcct tgggatacat aatcaccttg gcttacccgc
     3421 ttggacagga cgataccgct cgtgttcgac ttgatctcta caaccgggga gatagagccg
     3481 gacttctcga tagcggcgat ctgggcatct gtcatcttcc ataaatatag tttttcacgg
     3541 gcggcctgta tcaattgaga ttgtcccatg cggatcgctt ccaacaattc ttgctgggcg
     3601 gtgaaaagct ctggggagta gagggtagcg agggtctgtc cggcacgcac cgtctcaccc
     3661 gtgaaatcaa cgttcaagct ctcgatgcgt ccgcttacat gggctgtttg agattgcagg
     3721 ctacgctcgt ccggtacgat cttgccgtat aaacggactt gcttgaccgg attctggcgg
     3781 gataccttgg aggtttgtac gtccgctaag gctgctgctt cttccgaaag ctgaatggcg
     3841 ttgggatcga tggccttgtc ggagaaggag ctcttacgta cagggatcaa atccatggcg
     3901 cagatagggc atttacccgg cttgtcttgg cgaatttggg gatgcatgga acaagtccac
     3961 tcgccggcct cgttctgttg gaggtcgtgg ccatgcgtag gggcgtgaac ttccgtgccg
     4021 gtctcgctcg cttgtgacgt atggctgtcg gtatcggagt tatggaacag gagccagccc
     4081 aacaagaggc cgcccgctag gaacaggata tatatcaggt acttggattt tacggtttca
     4141 tttatatttt tcattttctt attcgtttac agaggtggat attaatttct cgattccggc
     4201 gatttgggta ttatattccg ctatcgcttc gcttttcttc aagtgatagt ccaacatttg
     4261 tcgctccact tggatcacgt cggtcaaggt cgttcttcct gtcgagaatt cccggacgat
     4321 cagttggtag gtggccaacg atagatcgta ttgtttctgg tacaaatcga ttttccgtgc
     4381 ggcatcttcc aattgctggg taatacggat atactcggct tgcagttggt tcatcgtgtt
     4441 ctcgtacttc aactcgctgg atttccaata atgcttgctt tcccgttgct gtgcgttata
     4501 tttcttacgg aagataggaa ggctgatctt tagcatgggc atgaacatat cctttccgtt
     4561 cataccggac atagagccca tagacatatc ttccggtttc ttcccgatca aggaatactg
     4621 gaggccgata cctagcatgg ggtaactcat tttcttgtcc atctccgcct tggcccggta
     4681 agcgtttcct tccgcctcca gcatggtaag catggggttg ttggagatga cgctgtcaag
     4741 agccatcgac tcactccatg agagaggaag ccgttccaac gagtcgggga cggaaatcgg
     4801 ggtagctagc gactgattga gcaacgtatt aaaagcagcc tcggccgttt tccgttgcga
     4861 taacaaggag gctagcgtat tctccagttc taccttctcc atctggattc gcagtacgtc
     4921 cgacattccg cccatggagt tgccacttcc catagagcct ccacccatag ggctaccgcc
     4981 ggacattccg gacatcgtac taccggatgc tcccgtgctt tgtaccgtag ggcttcccat
     5041 gctactgcct cccatacccg acatacctcc accggatacg gcgggaggag tcgatggagc
     5101 agaagatacg ggggagggta ggacggagga accgcccgcc ttcgccgacg gagcggagaa
     5161 gcggttcaat gccaactgtt ccaactggtc tagcagacga aggttcgcct gcgtattttt
     5221 atattgctcg ctgatattgc aaagctggta ccattgactc ttcacctcgt aatacaggtt
     5281 gttgcgactg ttacggaatt gttcgtaagc catccgggcc atctcggtcg cctcgttgcg
     5341 ggccgccttc cgggtaccga accaagggaa catttgcatc aaggtgaaat ccgctatttg
     5401 ctttccggac aagatctcca tcggtttcag gaagaaaccg atctccagtt ccgggtccgg
     5461 ataggctccg gcttgcggga ctttctccaa agatgcctta tacagggaga agtcggcgtt
     5521 gatctgcgga ttgttacgtg ccgccagttc cagataatag cctaaactat cggccggctg
     5581 ggagtaagcg aaaaggacgt ttagcatccc cagtacacct gccatgatga ttgatctgat
     5641 tcttttatat ctcataagtc gttacctcct cttgaatttt attcttttgt tctttcttta
     5701 tagcgttctc ccgccaccag cattgcagga cgggaacgac aaacatggtc atactctgga
     5761 tcagcatgcc tccgaacgta gggatagcca tcggtaccat gatatccgcc cccttaccgg
     5821 tagaggtaag tacggggagt aaagcgatca gggtagtggc tgtagtcatg gccgctgggc
     5881 gtacccgttt cagtccggcg gctactaccg cttcccggat atcgtgcttg gtgcgggggt
     5941 ctcgctcgag gaatacatga tggatgtagg ttcccatcaa taccccatca tccgtagcca
     6001 caccgaacaa ggcgatgaaa ccgacccaga ctgccacgct cagattgatc gtgtgcatct
     6061 ggaaaagatc ccgcatattc tctccggcga tggagaagtt catgaaccaa tcctgtccgt
     6121 aaagccatag caagataaaa cctccggcga aggccacgaa caccccggag aaatggatca
     6181 gtgaggcagt gaccgtcttg aattgaaagt atagaaccag caggacgatc aacaaggcga
     6241 ggggaacgac gatcatcagc cggctggtgg cacgctcctg ctgctcgtaa ttgccggcga
     6301 acttatagga tacgccggga tcaaggttca actcgccctc ctttatctgt tgctcaagga
     6361 tgcgggaagc ctctttcacg acatccactt ccgccttccc cgccagtttg tcgaagatga
     6421 cgtagcctac caagaaagtg ttctcgcttt ggatcatctg cgctccacgg gtatagttga
     6481 tatcggctag ctctttaagc gggacttgcg ccccagtggc ggtcggtacg aggatcatac
     6541 ctagcgcctc cggattatct cgaagctcac gagcgtagcg taggcgcacc gggaaacgtt
     6601 ccctgccttc cacggtgcgg gtcagtacca tgccaccgac agcggcactt aatatctctt
     6661 gcaagtcctc cacgtttacg ccgtaacggg ccatattctc acggttcagt tcgatctcca
     6721 gataaggggc gcctaccgca cggtcgtaaa atacggaaga ggggataacg gagggtacct
     6781 ctttcaatgc cttctcgatc gcctttccgg ctttctcgat cgtctccaga tccgggccat
     6841 acaccttgat acccatcggg gcacgcatac cggtggataa catgacgaga cgggcctcga
     6901 taggctgcag cttcggggcg gaagtcaatc ccggaagatg ggtgacgttc acgatctgtt
     6961 gccagatatc gttcgtgttc ttgatctccg gtcgccattg gcggaagtaa tcgcctttag
     7021 cgtctgggat caggctgtct gagggaatca gccggaaacc gtctttgggg ttatatacgc
     7081 ctccatcttt taggagatac tccccttgcc ggtttacctt gaaacgttcc cttttcccgt
     7141 cctcattcag gatatattcc ggacggtagt tgatcgtatt ctcgaacatc tgtaccggcg
     7201 ctggatcgag ggcggagttt acacggcccc atttaccgat ggcggtctcc acctcgggga
     7261 tagaggccag ccgtttgtcg agcgcctcta tataatcaag gttttgctcg ataccggaat
     7321 gcggcatgct agtcggcatc agtaggaaag aaccttcgtt caggctaggc ataaactcct
     7381 gtccgatgcc tctccatatc cagaaaccga atacgatagt agctcccgga atcaacatga
     7441 atttccagcg gttatccaag caccagcgca atatcctctc ataataaata acgagcagcc
     7501 acaggatgct taggatgatg gctacgcaac ccgccacgaa caatatattg gcgagcatcc
     7561 ctttttgcgg ccccatcggc aaccattcct cggataggta atagatcgtg acaaagaggg
     7621 tgataccgat attgatataa gtgctcattt gaggcttctt ccaataaccg gacaatagat
     7681 tattcacccc gactgccgtt agcccgatag ccggaatact tccataaata ataagtaagg
     7741 cgattccggc cacgatcaac aggtaattca gtattttccg tatctgcctt gaatggatct
     7801 ttatcgagaa taaccaatac gatagggaag gaagcaagat caatcccagc acgaaggcgg
     7861 aagccaaagc atatgtcttg gtataggcca aaggcgagaa catcttccct tcctgcgcct
     7921 ccatggtgaa gacggggagg aagctgacga tcgtcgtgat catcgctgtg ctgattgccc
     7981 cggacacctc gcttaccgcc ttataaataa ggttgacaaa cgcctttccc ccctgtatat
     8041 gtctgttctc gggcatctcc cggtaacgga tgatactttc cacgaagacg acccctacat
     8101 ccaccatcac gccaatggcg atcgctatac ccgataaagc cacgatattc gccgctatcc
     8161 ccgtataacg catgatgatg aacgtggcga gcaccgctat cggtagcatg ctggcgataa
     8221 cgatagaggc cctcagattg agcaccagca cgatgataac gatcacgcag atcaatattt
     8281 cgtgggagag ggcggtctcc aacgtcccga tcgtctcctt gataagcccc gtacggtcgt
     8341 agaacggcac gacggttacc ttggagaccg tcccgtccgc cagtaccttc tggggcaatc
     8401 ccggttccat ctccttgatc ttcgccttta cgttattgat aacctccaag gggttggagc
     8461 catagcgggc tacgaccact ccgcccacgg cctccacacc ctccttgtcc agccctcccc
     8521 gtcgggttcc ggggccgata ttcacgaacg ccacgtccga tatgcgaacc ggtacgcctt
     8581 cccgaacggt gatgacggca ttctctatat cttttacatt cttgatatac cccaagcccc
     8641 ggatcaggta ctccaccttg ttgatctcca tcgtctcggc gccgatatcg aggttgctct
     8701 tcttgatggc gctcatgata tccatcacgg agacgttgaa ggcatacatg gcatccgggt
     8761 tcaattcgat ctggtactcc ttcacgaagc cgcccgccga ggcaacctcg gataccccct
     8821 cggcggagga taaggtgtac ttgacgtaga aatcctgtat cgtacgcaac tcctcggcgt
     8881 tccagcctcc ggtaggttta ccggtcttgg ggtcccgtcc ttccagcgta taccaataga
     8941 tctgcccgag ggcggtagcg tccggtccca aggtaggctg tacgccttcc ggcaaggttc
     9001 ccggaggcag ggagttcagc ttctccaata tacgggaacg gctccagtag aactctatat
     9061 cgtcatcgaa gataatgtat atgaaggaca tcccgaacat ggaggaacta cggatcgtct
     9121 tcactcccgg gatacctaaa agagaggtgg tcagcggata agtgatctgg tcctgtatat
     9181 ccttcggcga gcggcccatc cattccgtgg ccacgatctg ctggttatcg ccgatatcgg
     9241 ggatggcgtc taccggaatc ggattccggg gaatgatccc cccgtgccaa ttgaaggggg
     9301 acgtggagat gccccatacg ataatcagca ctagtaaaag taaggttacc accctgttct
     9361 caaggaagta acgaatgatt ctgtttaaca tttgaatgag cttttatgat ttgaaaacat
     9421 atgagaacgc ttatttgttc gtctttgaag gcaagcgatc acatgagtac tcgtgatgct
     9481 ttacgccagt actcgcaatg gattactcca gtatttgcaa tggattactc cagtatttgc
     9541 aatggattac tccagtactt gcggtggatt actccagtac tcgcaataga ttacgccggt
     9601 actcgtgcgt aaacagacgt aaatcgcctt ttaaaaagga agcctatacc gctaaatcaa
     9661 aaaagtacaa tgatggacga ataacgggat agcgctattc tccttgggtg gattaataaa
     9721 gggattggaa cgtgttgtct cgtctcgccc ggcgatctta taggagtcga gtagatcgaa
     9781 caacaaaact acagcgacag gagcggacaa ttgcacgagc gtattcgcca catcctgatc
     9841 gacggataac ttaacatatt ccgtctcggt agagcagcac ttatgggacg tgcccgcctc
     9901 accgcaactg gggcaagtgt caagatactg caaactcacc tccgccaact tacccataca
     9961 ataatggtaa ttcagcgcaa acccggagga aaccccgagg taaaaaacag cgagtatgaa
    10021 caataaaaat cttctcatcc caagtaatat attccgcaaa tatatgaata ttttttgaac
    10081 gggcaatagg gtggaaaaag tgctcgtagg gttgttaaaa tcagaacctt ttctttatag
    10141 ccttgttcaa ggtaggtaat taatctaaac aaaacacatt tatgagacta tttgtacaag
    10201 gagcagtatt actgctaggt atgggattct tatcggctcc cgctaaggct caaaaggtgg
    10261 tcatcgagga tgacgtgcca aattcgatag tccttgtcag ccaagacaag gcaggtgatg
    10321 aaatcgtgag gataatgaat gagacgcaga gccctcgttt ccacgacccg aaagcccccc
    10381 gcttcgtatt gaccgatcgt aagggacgtt tcgccttggg tatcggcggt tacgtgaagg
    10441 ctacggcgga gtatgatttc ggcgggattt cggatgatgt cgatttctat ccgtccatga
    10501 tcccgaatgg tgggcagaac tacgtccgta accagttcca gatggacgct actaccagta
    10561 cgatattctt gaaattaatg ggtcgtacca aacacctcgg ggatttcgtc gtgtatacgg
    10621 cgggtaactt ccggggaggc agcaaggtct tcgagctcca gaacgcctat gtgtctttcc
    10681 ttggtttcac gatgggttac gattatagta ccttcatgga tctggccgcc cttccgccct
    10741 cgatcgatta tgcggggcct gccggacagg ttttcagccg tgccaccctg ttacgctatg
    10801 agcgtgcttt cggtaaggga tggaaagcgg gtgtaggtat cgagatgcca gtggtggatg
    10861 gcatcacgaa ccaaagcgtg aatatcagta accaacgtat gccgaacttc cctgcctata
    10921 tccaatacgc ttggaataag agcagccata tccgtgtagc tggtatcgta cgtaatatga
    10981 cgtacgagaa cttggtggcg caacgggccg agtctaaggc cggatggggc gtgtttgccg
    11041 cctctacgtt caatgtgacg agcaagctga acttctacgg tcaggctact tacggccggg
    11101 ggatcagcca gttcttgaat gatatcagta atctggacgt ggatctggtt ccggaccccg
    11161 aggccaaagg caagatgcaa gtgcttccga tgatgggttg gtacgctggc ttgcagtata
    11221 atatcacgcc gaaggtattc gtctccagca cctatagcca gactcgttta tacagcgaga
    11281 atgattaccc ggttaccccg tcggatcaat accgctacgg tcaatacttg gtagccaaca
    11341 ttttctggaa cgtgaacgct aatctgcaag tcggcgccga gtacttgaga ggctggcgta
    11401 ccgatttcaa cgatatgacc cgccacgcca accgacttaa tgtttccgct caatataact
    11461 tctgataatg tagcgttttg ttgatgtgcc acaccggggg attcttggtg tggcatttct
    11521 tttcgaggcg attggcaggt ctgcgattaa tagatgttcg ccatgctaat cagcggctca
    11581 tacagcttct cgatatcctg cgaatcgatc tcgatttcta cttgatcacc ggggataaga
    11641 gtctgtccgg cgggagccaa gtccttgcga tcccggtgaa tagtcttgat gatacaacgt
    11701 tgggggaggg tgaggtgatc tacctccttc ccgtcgaaat aggcacctgt catgatctct
    11761 acgaacaggc tggaacgccc ttcggtacgg aaggctggag tcgagatcat ctcgtcatag
    11821 agaaccacgt taaaaggttt tatctgtagc atttccgtga agtaatacgt aagcccgccg
    11881 acaatgatag aggggtagaa tacgtccaga tgcccggtta tctccgtaat caagacgata
    11941 cccgtcagcg gtgtccggac taccgccacc aagaaaccta ccatgctgat taacatgata
    12001 tagctgatgc tctccgtttc aatgaaacca tacttcacca ataataaggc gatgatctgc
    12061 ccgaacaatc ccccggtaac tagtgtaggg atgaaattcc ctcccggcag tccggaggag
    12121 aaagagagag acgtgaatat caagtggatg agcatcatcg ccgctatcca taaaacgggg
    12181 tgatatccat gcatcgcttg catgataagg aattgctcgc ctcctcctgt caagtcgatc
    12241 tccgtcaatg agatcgtata cgctatgata agcaggtaca acatcttcat ataaggagga
    12301 tgcttcagtc tggtaaagaa atccttgcac caaagggtaa acatcgagta aattttcccg
    12361 aagacggaaa taaccacggc cagaaataag aacaacttca gttgatctat aaaagtagcc
    12421 tgcggggcaa tagcgctaat ctgcgagtag gggttgaagg ggaaaatcaa gctcgctacg
    12481 cctcccgcca cgacccctgc cagcaaggtg gtaatggcgg tcttgggagc gtcgaaccgt
    12541 tcgatggact cgatcaccaa aagtgaggaa gcgaggggag cggcgaaagc ggcggccaat
    12601 ccggcacctg cgccggcggc caaaagttgc ttgcgctctc cagccaatac gtgtccccat
    12661 ttggaaatga tattccccac gtaagatccg atctgtacgc acggcccctc acgaccaagg
    12721 gacaggccgg cgctgatcgc taatatccct cccgtgaact tggcgattaa ttgtgtcaat
    12781 gggtttttat aagtgatcct gccattgata accgcccgtg tctggggaat gcccccaccg
    12841 gtaatcagcg gcatcttctt gaccatccaa ttcacgcaaa gcaatatacc ccatagcgtg
    12901 aagaagaaca agacatggaa ataccaaggg taatgaccgt cgaaaaaaag tttccggcta
    12961 ttgaataact gctggagcag atagtgataa ggtaccgcta ccaacccggt cagcaatccc
    13021 acgaaaatgc ttacaaaata aagtctggcg tcaataagtt tcaatttcca gatccgccag
    13081 cgcctcaatt ttgttatatc taagagatca ttatccatcg gactcacctt gttttcgttt
    13141 cctgttacaa caaccaaggt aaataagagg tttaaaatct cattccattg aacctttttt
    13201 aaaaagcctt gttattaaga tatagtgttt ttcatggtat tagaattaag ttagattagg
    13261 ttatccgtct tgttcgtgag aatagggcgg ttttcctgtt tataggggtt tgtactttga
    13321 ggcggttagg atttcttggg cgtcgttgtt ttgcatcaac gcctccgggg tagatcccgt
    13381 ctccttcatg tactggttga tgatctgcca gcctatccaa gtcccgatat tcccgggagc
    13441 gtcgttctcg gggaaaatgg ccggggtatc ctcgaaatac tgggaagttg tcagttgatc
    13501 cggggtataa agatgcttgc gctcgatgat tgctttccag attgttcctt cgttgtcctt
    13561 gcaccagttg taggcctgtt cggtgtatcc cattagctcg gcggcatcgg gaacgcctag
    13621 ggcttgcgag agcaggtatt tgatttttcc ctcgtaaatc atccggtcca gcaatacgtt
    13681 ctcttttccc gcgaaaggat attcggacat gagccacccc gccagataat ccgggactac
    13741 gagtccacgt tgcattttca atttctggga gtcatagaag aaatcttggt acaagggata
    13801 gtcctttccc atatacttat cgatggaaag ggaaagcagg ctatcgccta ccaatacgtt
    13861 ctggttgaaa ccggatacat gcatatagat agcagggatc tgcatcgagg ggaaattctc
    13921 ctttagatag gcgaatccgt atcccaagga tttctcgata tcctccacgg aatcatattg
    13981 ggtgatagcg tcacgataca agcctttcaa ggtaggctcc gagtaataat tccgcatttt
    14041 ctcgaagaag ccgggagtct cgatggtttg caggtttaat atgcctttcc cgatgatatc
    14101 cagcatttcc gggtattgtt tgattagttc gggttgcaag gtggtatctt ccgtatcgat
    14161 cagccggaat aaatccttgt caaaacgatt gatatgcagg ggttcgacgg tagcgtagtt
    14221 gatcgtattt gtgttttgcc cgttgcagct caatagcgta gcggacaaaa tacaggccat
    14281 gatgagtttt gtaaccatat ctcttcgtat aataatgtaa tatgataaga aacggatcgc
    14341 atggggtaat attgtgtgac tggcatctta ttactacctt tgcctccctt ttatttaaga
    14401 ttcatcatgc gatatacgaa caaacaaatt ctaaagatca cgtatccggt attaatcagc
    14461 ttgctcatgg agcatatgat cggattgacg gataccgctt atctgggacg tgtcggcgag
    14521 gtcgagctag gtgcctccgc cttggcagga gtctattatc ttgtgattta tatgctgggc
    14581 tttggtttca gtgtaggcgc tcaggtgctg atggcacgtc gtaacggtga gggggagtat
    14641 aaacggatcg gcgaggtttt cacgcaaggc gggctattcc tttttttgct ggcggcggtg
    14701 ttgtttacgg cctctaatct gcttacgccc catctgctcc accggatgat cggttcggaa
    14761 gaggtgtatc gagcgacgat gagctatctg gactggcggg tgtacgggtt cttcttctct
    14821 tttatagcgg tgatgttccg tgcgttttac gtgagtacga cgaatacgaa gatcttgacg
    14881 gccaattcgg tggtgatggt gcttaccaac gtggtcttga actatatctt gatattcggt
    14941 aagttcgggt tccccgcttt ggggatagcg ggtgccgcta tcgcttcctc gatctcggaa
    15001 gctgtttccg tattgttctt cgtgatttat acttggaaga agatagatta taaaaaatat
    15061 ggtctgttcc gttttacgag agtggatttt aggatgctgg gacaaatact tagtgtctct
    15121 atctgggtga tgatccagca tgggatcgct tttggaggat ggtttatctt ctttatcgct
    15181 atggagcatc tgggtgagcg gccgttggcg attacgaatg tggtacgtag catctcctcg
    15241 ttcctgttta tgttcgtgaa tgctttcgcc tccacgaaca gctcgctggt aagtaacttg
    15301 atcggtgccg gggagtcgga ccgggtgctt ccgctttgcc ggaggatgat cgggctatgc
    15361 tatgcgttcg tgctaccgat cggtatcttg atcgctatgt tcccgtctac cgtattgcgt
    15421 atttatacgg ataacccgga cttgatcgct agctcgatct cctcgttgtg ggtgatgctg
    15481 tcttcttatc tcttcgctgt tcccggtttt atttatttct ttagcgtatc ggggacaggc
    15541 aatacccgcc gtgcgctgga aatcgatatg gctagcatat tcgtgtacgt attatatata
    15601 ttgtatgtcg ccgtatggtt gcgtgcggac gtggcggttt gctggactac ggagtatgta
    15661 tataatatca tgatcctttc ttctttcttc tatctatgga aaggaaattg gcgtaacaag
    15721 aaaatctgaa gacttatctt ttgattagta cggtaattcg taaggataaa tcaaaaaaga
    15781 ccatcttggc attcacgttc tgtgtgatat ggcgttccgc tttcgccaat tcttccatca
    15841 aatcgatcac gtttcgctcg ttgacgaaag gggagaactt aacggagaag ctagcctcgt
    15901 ccagattcat ataattaagt tccggcgatt ggaaccggta catgaagttc tcccggatca
    15961 aatgctgaca ataggagagg aagtttttct gtcgttcccg tccgatccct gccatgacgt
    16021 ccgccatcgc tttcatgcct tttacgtttc gtgcccatga gtttcgcatc atggccttga
    16081 attgctccag aaagaattta ttttcctcgc ccaagctaat cgcctccatc gccttgataa
    16141 aacttccgga ggagaggtga gcgacgtgtt tagcgtcgtc gggcgaaagc ccgaaacggg
    16201 ataccatggc attcatgatc gcatcggtct caatgggacg gatgtggatg cgttgcgcac
    16261 gggattggat ggtcccgagg ataaggtccg gtgtctcgga taccataagg ataaccgttt
    16321 tcataggagg ctcctctatg attttcaaaa gcttgttggc gcaagtagga tgtagtttct
    16381 ccggcaacca aaccatcagg atacgatatt ccgcctcata aatctttagg ctcagtttat
    16441 ggataatctc atcgctttcc ttggaataga tgatcgcttg tgagtttccg gcctcgatat
    16501 aatccagcca ttcatccata ttgaaatagg gatgttcttt gaggaaccca cgccattcac
    16561 tgagataatc atcgcagacc tctttctttt tctctttctt ggctacgatc gggaatacga
    16621 aatgcaaatc gggatgtgcc aattcgtcat atttaaggca tgacgggcaa cgtccgcaag
    16681 cgtccgtctc cgtccggttc gtacaattca gataacgggc gtaagccaaa gccagcggaa
    16741 acgccccggc ccccccttgc tccgtgaata actgcgcatg gggtacgatc cctgtccgag
    16801 tcgattgcct caaccgttcc tttacttcct cttgcccgat gatatcttta aaatacatga
    16861 gatatttcct tttctataga ataaggaacg aagttacgga aaagtattca gatatcaaaa
    16921 ggtgcggggt tttgtaaata tcaattgaca tatatagagt aaaactaaaa acggatacaa
    16981 taacaagtca agtccaataa agaatatgta tttcattacc ttagaatttt aaaaataacc
    17041 atacttagta catgattgtt caatcgtgta cttctattag acaactcagc gtggaaaaac
    17101 ccctattgta tctcaataaa tttcttttgc tattttgtaa acgctatccg aggccatcat
    17161 tgtgtagaaa tgtaagctcg gtacgccatg agcgatcaga tccttgcact gctgtataca
    17221 ccattccaca cccacctctt tcgcttccgc atcatcttta catttacgta attctgtcgc
    17281 gaaaggctct gggatatccg cacggaatat cttcggaaga accgttaatt ggttcttgaa
    17341 aacgatcggt ttgataccgg ggatgatggg aaccgtgata ccttccgcac ggcaacgatc
    17401 cacgaacgca tagtacttgt cattatcgaa aaacatctgg gttaccagat attcagcgcc
    17461 attttttact ttctccttta agtaatagat atcggattcc atattgggtg cttcctcgtg
    17521 tttctccgga tagcaagcca tgccgtacga gaagggagtc tctataccgt ctatcttgga
    17581 accgtctaac gcaatacctt cgttgaaatg atttacctgc tgttgtaaat cagttgcgtg
    17641 gtcgtgatat aactccggtt tttgctggga ggcctctaag gtctttatat ctccccttaa
    17701 tattaagagg ttgtttacgc caaggaagtt caaatcgatc aaagcgtatt ccgtctcgtc
    17761 tttcgtaaag cctttacata taatatgggg tacggcagga ataccgtatt tattctggat
    17821 agccgaagcg atcgctacgg agcccggacg tttacggatg tttactttct ggaaacttcc
    17881 gtctggtaag gttttataga cgaactcgct atgatgggag gtgatattta tgtatttagg
    17941 gtcgaattcc ttcaacttgt caatcacatt atataccttc tggatactgt tacctttcag
    18001 cggcggtaat atctcgaaag aaaaagcggt actcttacta ttccttatca gatcaatgac
    18061 tttcatattt taattatttt tgacgcgaat gtagcaaata tacttcgaaa tagcttacat
    18121 ttacgatcat taatctaaca aagcggctaa ctgagcgctt tcgtgtaaac taaggttttt
    18181 taaagcatgg acttaactta cttaaaaacg ctattgggct ttgtctcgaa tcgtacccat
    18241 gatacaacaa ctagtattct ggcttactgg gaagtgttgg aatattttca agagctgtca
    18301 ttccctcagg cttctaaatc tggtttaccg gaggatgagg tacgggtaag atatgtgaga
    18361 tcggaggatg agttgaagta tttcatatat gctccataca gggatgcgga tagcttccgt
    18421 ctgtatgtgg gaggtgttcc taaatatgat cttttgtccg agctatatcg tttgattccg
    18481 gcggataagg ataatgagcg ttttcgtaag ctgttggaga agaataaatc tgtaagcgtg
    18541 ctctatacga ttgatttatc cccgtccgga gagtacatag aaggctcgtt ccaactttcg
    18601 ccttatatct gggcgatcag ctgcttaatt catgaccggg aggttgatga ggagtggttg
    18661 gaggaactac tggaggatgg aaacgacttc tttatgacaa ttgaggatga ggaagggata
    18721 gagttcttct ctcttttgcg gcagaagacg gtagagttgc tagatcgact gcggatccgg
    18781 agtctattta ccgtaaatga tggatttaga aggaatgatt tggagcgggt ttgtgcccgt
    18841 gcgctaaaat cggatgatac ggacttaagc ataagcttct atgcgaaaga tttaagcagg
    18901 gttcgtaaaa gtctgctgga taaaaggccc aatcgtttac tggtgaacta tataaatgct
    18961 cctttgatga gtggagggaa ccgtcaaagt atatgctcaa tagagaatta taggaaatgg
    19021 ttaggtccgg aaagatatcc gctgggccgt tggccttctg agttcagccc ggcgttgatg
    19081 caacagatgg ctattaatat agcgttggcc gaagaaaatg cgggaggctg tggcattttc
    19141 tccgtgaatg gccctccggg aacgggtaag acaacattgc tgaaagatat tatcgccgag
    19201 tacgtggtac ggcgtgcccg gttattagcg gatttgaatc agccggatga tgcctttaca
    19261 gagactccgc ttttagtgaa gtctttggag gcaggtaaaa gtcagaagac atttggtttg
    19321 cagacgggac ggggattggc cgattatgga attcttgtga catcctgtaa taatacggct
    19381 gtagagaata tcaccttcga gttacccgag acgagtaaac tacctaccgc tgaagccatg
    19441 tcaaaagccg ggcactctct agtctttagt gagggtaaag atttattttt cggagatttg
    19501 gcttccaata tgctcaatgg aaataccgat ccgggaaaac atacgaaaca ggcctgggga
    19561 ttgatatccg cccgtttagg aaaaggggat aatatccgtt ctttcagcga aatggtatta
    19621 aggccgtttg tttccaagat gagtcctaaa agagacaatg agaaggttat gcgggagttt
    19681 aagaaccgtt tcccttcttt cgatatcgct caacaagagt tcttgaagca atatcgaata
    19741 gtggagcgat tgcggcggtc ggtctcttgt aacgaagagg tatttaggat ggcggacgag
    19801 aagatgcagt cctcgaatcc tttgaagaac gctgaattcg acaaagcaag ggaagatcta
    19861 ttttatcaag ctttggtcct gcatggctct tttgtgatca attcctacaa atggcgttgc
    19921 aacctttatt cgctgttggc cttttgggat aataaatata tgccggagga gaaagaattg
    19981 atattctcac atgtgttgaa tagcttgttt ttcttggtgc ctgtggtatc taccacattc
    20041 gcttccgtac agaagatgct ggagtacatg ggtagggagc aattgggatt gttgatcgtg
    20101 gacgaggccg ggcaagccgc tccccaatgt gcggtaggcg ctttgtggcg ggcaaagaaa
    20161 gcgatcatcg tgggagaccc gaaacaagtg gaaccggtag tcaccaccga tgagacgttg
    20221 atgactctct atcaaaagaa atgtggtatc gtatccttgt cttcttacct ctcgaaatcc
    20281 cattccgtgc aaggtttcgc cgatttgata aaccgttatg ggtcttggat tggagagacg
    20341 tgggtaggct gtccgttggt cgtgcaccgt cgttgtatca atcctatgtt tagcatctcc
    20401 aaccgggtgt cgtacgacga tacgatgatt ctgggaatga aagatgcggt gaaagacgag
    20461 gagaaaagtc aattgttgct agatcattcc ttatggatcg atgtgcccgg taagaaaggt
    20521 actagcgcta aagggaataa tgatcattac gtggcggagc aaggcgaggt atgcttgcgc
    20581 ttgatattgg cgtggatggg aaaacaccgg gagaaagagg atacccggaa attatatgtg
    20641 atctccccct tcaccacggt tgtgaaaggc attaaggctg cggttaaagc cgtcttgaat
    20701 acggaggagt atagtgggct taaaggtaaa tttaaggggt gggagactgc caactgcgga
    20761 acggtccata aattccaagg aaaagaagcc gaggaggtta tcttcctgtt gggatgccaa
    20821 ccttcttcaa ctggtgcgat aggttgggta aatagcaata tcctgaacgt ggcggttacc
    20881 cgggcgaaga agcgggtgta ttttatcggg gattatgagg tgtggtctcg gcagaaccgg
    20941 aatttcagcc cggagattat ctgtttttcc gaggaggata cagggcttca acgaatacat
    21001 ttctcggaac ttccggattt tggggagatc gaggccatgg aagagactcc agacttagaa
    21061 ttcccgggag cagaggatag ccaagtagaa tatttattgg aagaagatga gatcgatccg
    21121 gaaacaacgg aaccggagga tagaaagcaa gatatacgcc ccattccaag atactcattc
    21181 ttgactggtc cggaatacca tcaccgttac cgggtgattt actcgcatcc ctatcaactg
    21241 atatttgagg tcttgatgac cgatccgacg gagactttac cggatttacc ggtttctttt
    21301 taccgtaagt tgtccgattc gccttcctta tggatgtgtt tgatctatcc ggtcgccctt
    21361 gatttcccag cgcaagagtt ggagaatgag ttcgaccaag tgatagattg gtataattcg
    21421 ttataggccg aaatgtagcc ttccgcttgc tttttttagt ttataggccg aactatatat
    21481 aaattagcgt atatttgcgg tacacaaaat ctcccatagc gacggctatg ggcgtttttg
    21541 cttttgagcg atattattaa cagtgtaatt tgttaatttt aaactaatta cagcaaattg
    21601 tatagatatg gaaaatttaa attggtctga gctgggattt ggttatatca agacagacta
    21661 caatgtaaga tgctactatc gtgacggcaa atggggtgag ttggaagttt cttcatccga
    21721 gattatcaat attcacatgg ccgctacttg cttgcattac ggacaagagt ctttcgaggg
    21781 cttgaaggcc ttccgcggga aagacggtaa gatccgtgta ttccgtatgg atgagaacgc
    21841 taaacgtatg caatcttcca gccggggtat caagatggct gagttgcctg tagagatgtt
    21901 cgaggaagct gtacgtaagg tcgtgaaatt gaacgagcgt ttcgttcctc cttatgagag
    21961 cggtgccgct ttatatattc gtccgctgat gatcggcttg ggcgctcagg tgggtgtgaa
    22021 gccggctccc gaatatatgt ttatgatatt tgtcactccg gtaggtccgt atttcaaggg
    22081 tggattccag ccctcgaagg tatgcgtact tcgtgagtac gaccgtgcgg ctcctaacgg
    22141 gacaggtacg atcaaggtcg gtggtaatta tgccgctagc ttggtagccg gcgagatcgc
    22201 tcattccaag ggatacgccg ccgtattgta tctggatccg aaagagaaga aatatctgga
    22261 tgagtgcggt ccggctaact tcttcggaat ccgtggcaat agctatatca ctccgcaatc
    22321 ccactcgatc ttgccttcga tcacgaacaa gagcttgcag caattggccg aggatatggg
    22381 cttgacggta gagcgtcgtc cggttccttt cgaggagatc gctacattcg acgaggctgc
    22441 cgagtgtggt accgccgcgg ttatcgcccc gatctcgcaa atcgacgatt tggacgagaa
    22501 caaatctttt gttatcgcca aagatggcaa accgggtcct gtttgcgaga aactatatca
    22561 taagctacgt gccatccagt atggcgacga gccggatact tacggatgga tctcgatcat
    22621 tgaataatat cttttgtttc gtaaggactg gagtgcgctc cgtctttacg agacagaata
    22681 cgttgatagg caattgttag tttgaacttt actttttgca ataaaattgc aatctccgca
    22741 ttgcaaatga gaaaagatgt ttatctttgc atcggtaatt ccaaattttc aattaccaat
    22801 tatgtaggtg gaagcattct ttaaaacaca taaatatctg gtagagcatc tgtattctcc
    22861 ggtacgaagg ggattgatgg atgagatcaa ttgggaggat cggttgatcg gtattaaagg
    22921 ttcgcgagga gtcggaaaga ccactttctt gttagactat gcccgtgaat attttggtgc
    22981 cgataataag gaatgcttat acattaattt aaatcatttc tattttacgg aacgcacact
    23041 cgttgatttc gccgccgagt ttcgggctaa aggcggaaag gtgttgttga tagaccaagt
    23101 gtttaagtat tccaactggt cgagagagtt gcggtattgc tatgataatt tcgaggactt
    23161 gaagatcgtt ttctccggct cgtcggtgat gcgtctgaaa gaggagaacc cggacttgtc
    23221 cggcaaggtg gtatcgtata acctcagggg gttctcgttc cgtgagttct tgaacttgat
    23281 gtcggggaac cagttttccg cgtacacgtt cgatgaggta gtagagaatc atcaggaaat
    23341 cgccaaacgt atttgctcgg tcgtaaggcc gatggcttat ttccaagatt atctccatca
    23401 tggtttctat ccgttcttct tggaaaagcg caacttctcc gagaatctgc tgaagaccat
    23461 gaacatgatg ctagaggtgg acgtgttata cataaaacaa atcgaacaaa gctacctacc
    23521 aaagctacgc aaactactct acttattggc tacgagcgct ccttgtaccc caaacgtgag
    23581 tcagttgagc aaggatatcg agacatcccg ggccaccgtg atgaactata tcaagtattt
    23641 gacagatgct cgtttgatga atatgctgta tccggtgggc gaatcctttc cgaagaaacc
    23701 ctccaaggta tatatgtata actcgaacct gatgtacccc atccgtccga tggaggtaaa
    23761 tgccggggcg gtgcgtgagt cgttctttta taaccaacta ttgaaagaca ataagctgaa
    23821 tgaaggaatc aagaacgccc actttctggt gaatacgatg tataatttcc ggatcgagga
    23881 aaacatgaaa gtgaagaaca atccggatat gtactatgct gtcgataaga ccgagatcgg
    23941 ggaggggaac atgatcccgc tttggttgtt cggttttcta tattaagtaa gaatcttttt
    24001 taatactaat agttttatag gtctatgaca aaacagaaga aatttttaac ctgtgatggt
    24061 aatcaggccg ctgctcatat ctcgtatatg ttcagcgagg tagccgcgat ttaccccatc
    24121 actccgtcgt ctacaatggc tgaatatgta gatgaatggg ctgcagccgg acgtaagaat
    24181 attttcggcg agactgtaat ggtacaggaa atgcaatcag agggtggtgc cgcaggtgct
    24241 gttcacggtt cattgcaagc tggtgccttg acaacaacct acactgcttc tcaaggtttg
    24301 ttgcttatga tccctaatat gtacaagatc gccggtgaat tgcttccttg cgttttccac
    24361 gtatccgctc gtacattggc ttctcatgcg ttgtgtatct tcggtgacca tcaagacgtg
    24421 atgtctgccc gtcagacagg tttcgccatg ttggccgagg gttccgtaca ggaggttatg
    24481 gacttggccg gtgtagctca cttggctacg atcaagtctc gtgtgccgtt cgtgaacttc
    24541 ttcgacggtt tccgtacctc tcacgagatc cagaagatcg aggctttgga gaatgaggac
    24601 ttggctccgc ttatcgacca gaaagctttg gctgagttcc gtgcccgtgc cttgaacccg
    24661 gagagaccgg tcgctcgcgg tatggccgag aacccggatc atttcttcca acacagagaa
    24721 tcttccaaca cgtactacga ggcagttccc gctatcgtag aagaatatat gaacgaggtt
    24781 tccaagatca caggccgtaa atacggtttg ttcgattatt acggagctga ggacgctgag
    24841 cgtgtgatca tcgccatggg ttctgttacg gaggccgctc gtgaggctat cgatcacttg
    24901 atcgctaagg gcgagaaggt aggtttggta tccgttcact tgtatcgtcc gttctccgct
    24961 aagcatttct tggctgccgt gcctaagacc gctaagcgta tcgccgtatt ggatcgcacg
    25021 aaagagccgg gtgctaacgg tgagccgttg tatctggacg taaaagactg cttctatggt
    25081 caggaggatg ctccggtgat cgtaggtggc cgttatggtc tggggtctaa ggatacgact
    25141 ccggctcaga tcctgtccgt attcgagaac ttggcgttgc cgatgccgaa gaaccagttc
    25201 acgatcggta tcgtggatga cgttactttc acttctctgc ctcagaagga agagatcgcc
    25261 ttgggcggtg agggtatgtt cgaggctaag ttctacggtt tgggtgccga cggtacggta
    25321 ggcgctaaca agaactcggt gaagattatc ggtgataaca cggataaata ctgtcaggct
    25381 tatttctctt acgactctaa gaaatccggc ggtttcactt gttctcacct gcgtttcggt
    25441 gatcatccga tccgttctac ttatttggtg aataccccga acttcgtggc ttgccacgtt
    25501 caggcttatt tgcgcatgta cgacgtgact cgtggtttgc gtgagaacgg taccttcttg
    25561 ttgaataccg tttggggcgc tgaggagttg gctaagcact tgcctaataa ggtaaaacgt
    25621 tacttcgctc agaagaatat cactgtatat tatatcaacg ctacacagat cgccttggag
    25681 atcggtttag gtaaccgtac caatacgatc ctccagtccg ctttcttccg tatcacgggt
    25741 gttatccctg tagacttggc tatcgagcag atgaagaaat tcatcgttaa gtcttacggt
    25801 aagaagggcg aggacgtggt taacaagaac tacgcggctg tagaccgtgg tggcgagtac
    25861 aaccaattga cggttgatcc cgcttgggct aaccttccgg atgatgaggc tgtcgtaaac
    25921 aacgatcccg ctttcatcaa cgaggtagtt cgtccgatca acgctcagga tggcgactta
    25981 ttgaaggttt ccgcgttcaa gggcatcgag gatggtactt gggcgcaagg aaccgctaaa
    26041 tacgagaaac gtggcgtggc cgctttcgtt ccggtttgga atgaggcgaa ctgtatccag
    26101 tgtaaccaat gtgcttacgt ttgtcctcac gcttctatcc gtccgttcgt attgaacgat
    26161 gaggagcaga agggcgctag cttcgctatg ttggacgtga aggctccggc cgctatgaag
    26221 ggtatgaagt tccgtatgca ggtagacgtt ctcgactgtc tgggttgcgg taactgcgcc
    26281 gatatctgtc cgggattcaa gggcaacaag gctttgtcta tggttccgct ggaaggccag
    26341 ttggctgagg ccgataactg gaactactgc gtaactaacg tttcttctaa gcaaaacttg
    26401 gtagacatca agtctaacgt gaagaactca cagttcgcta ctccgttgtt tgagttctca
    26461 ggcgcttgct ccggttgtgg cgagactccg tacgtgaagt tgatcactca gttgttcggc
    26521 gaccgcgaga tggtagctaa tgctaccgga tgttcttcta tctactccgg ttctgttcct
    26581 tccactcctt atacgacgaa cgagaagggt caaggtcctg cttgggcaaa ctctttgttc
    26641 gaggatttct gcgagttcgg cttgggtatg gaattggcga acgagaagat gcgtgcccgt
    26701 ttggaaggct tgttgcaaca gatcaccgtg ggcgagcatg ctccggctga ggccaaggaa
    26761 atagccgccg cttggatcgc taaccagaac gacgctgaga agacgaagga attggctccg
    26821 caaatcatgg cattcgttga gcaaggcatc aaggagggtt gtcctgtttg cgctcagatc
    26881 aaggaattgt ctcacttctt ggtaaaacgt tctcaatgga ttatcggtgg tgacggtgct
    26941 tcttacgata tcggttacgg tggtttggat cacgtgatcg cttccggcaa gaacgtaaat
    27001 atcttggtat tggataccga ggtttactct aacacgggtg gtcagtcttc taaggctact
    27061 ccggtgggcg ctatcgctaa gttcgccgct tccggtaaga gggtacgtaa gaaagacctt
    27121 ggcttgatgg ctactactta cggttacgta tatgtggctc agatcgctat gggtgccgac
    27181 caagcccaga cattgaaggc gatccgcgag gccgaggctt acgacggtcc ttcattgatc
    27241 atcgcttacg ctccttgtat caaccacggt ttgaagaagg gtatgggtaa gtcgcaagct
    27301 gaggagaaag aagccgtagc atgcggttac tggcacttgt ggcgttacaa cccggctttg
    27361 gaggcagagg gcaagaatcc gttcaccttg gatagcaagg agccggattg gagcaagttc
    27421 caagacttct tgaagggtga ggttcgtttc gcttccgtag ctaaacaata tccggctgag
    27481 gccgctgagt tgtttgccgc cgccgaggag aacgctaaat ggcgtctgcg tagctacaaa
    27541 cgtatggctg ccgagaattg ggatgtagag gcttaatata acaggtcttt tagtatagaa
    27601 tgagggcggt gtctccggaa acggaaggca ccgctttttt tatggggtgg atgggggagg
    27661 ctgcacataa ggcgatacgg acctgtacta ccgtatgtgc cggcctgtac ttccttatgt
    27721 gtcatcctgc gttaacgtat ctacaagtcc gtactaacgt atctacacgt ttgcacgaac
    27781 gtatctgcaa atttacacaa gcgtatctgc aagtttgcac gaacgtatct acaagtctgt
    27841 actaccatat ctgcaagcct gcgctaccgt atgcgcggtt tctcagaaga ccggaatcga
    27901 atagaccagc cccagcgata tacggtgtgt atccggttct atggctccca ttcgcgtggc
    27961 ggctttctct aggataacgc cccggtaggt gtataggacg aatacgaaaa ggtcgagttg
    28021 cttgaagggg aagaattcca cgctactctg cgcgttccac gaacggcggt acatcccttt
    28081 ccggaaatca ccgttgctct tatacaccca ggcggtctcg tacgcccctt tcacgtaaac
    28141 gttccattgg gggtggacac ggtaatccac gtcgccgata atcgataggt attcggtgtt
    28201 catggcggta tgaggcgtgc cgggcagacg gctgacgacc ccatgttggt cgatcccttg
    28261 gcgggtatac ataacgtcga ggtacgttag caacgggcct ttctcatagg tattgccaca
    28321 ggtgaaatag taggagtagc gcttgcgggt ctgctgtccg acggcggtgg cataacgcag
    28381 ttgcaaggtc ttgtccagat aatagctatt ccagttgacc gtgtacataa agggtatctt
    28441 ggccttggcg gtaccctcgg gaagtccggt agggtagatg tcctcgtcgt taccgttgcg
    28501 gttattcacg atctggaaac aaagctcgtg atccgggctg acttgccagt tacccgagat
    28561 accggcttgg taggcggtca gtaaattatt gaactcgcta aactctcgta cccggatgga
    28621 attgacgtaa tactcgtatc ccccgaaatt aacgaattgc ttgccgatcg tgaaattgag
    28681 attatgccgt gccttcaggt tcacgtaagc cagctcgagc gaggaggaga ggttgtcgag
    28741 cgaataggga tcggagtatt tgttgaacga ctgccggtaa tgatacccca gccacttgcc
    28801 cacgtccccc ttgatctcca gccggacacg gttcagcttg aagttcatac cgtctagctc
    28861 gttcccgaca aactcagcgt tggccgaggt gaaaagctgg aagttcatct cggcgctatt
    28921 gatcttgatc tctccgttcg ataatcgttc cacgagtgta ggttccccgt tattctcccg
    28981 aagggtctct tgggccgtca ggctggcgtt cgtggctaga caaagcaaga aaagtagaaa
    29041 atgtttcctc atacgataga tttagttggt aacagcctac aaaagtataa aaaacgtctt
    29101 aaccaagata cgtttaaggg gatgaaaatg ggtgtttagg ggatgcggac tttcgtgcta
    29161 tccgcatccc gaggtgtata cgctttctct agcctccgtc tagaacctca attgagaatt
    29221 caattccggg aactgcgctt gatgccaata cgggtagatc ggggtcgtct ggcttgccat
    29281 atcgaggcgc ttcacctgct ccgggctgag gctccagcct atggcctcta ggttctgcct
    29341 tagctgctct tccgtgcggg cacctatgat aaggctgctt actgtaggcc gttgcaataa
    29401 ccagttcaag gcgcattggg ctacgctatg cccggtctcc tcggctacct gttccaatac
    29461 ctccacgatg tcgtacaggc gttcgtaaga agtagcctcg tcaggtatcg ggcttcctcc
    29521 gcgagcgaca cgcccgtccg tcgggatcgg gttattccgg cggtacttcc cgcccagacg
    29581 tccggcggat aaggggctcc agataatggc gcccaccttc tggtcgatgc ctagcggcat
    29641 cagttcccac tcgaactccc ggttcagcaa ggagtaataa acctgttggg ccacgtaccg
    29701 gctccatcca taccgctccg atacggaaag cgacttcatt aagtgccagc cggagaagtt
    29761 cgagcaagcg atataacgga ccttcccgct cgtcaccaag tcgtccaagg ctcggagtgt
    29821 ctcctctacc ggggtatttg cgtcgaaacc gtgcatatga taaatgtcga tatgatccgt
    29881 gttcaatcgt ctcaggctcg cctcgcacgc ctgtatcaga tggaaacggg aagaaccgat
    29941 ggcgttacgg ctctccgggc ttaggttgaa agtcgccttc gtggagatca agaggcgatt
    30001 cctcaatccg tggatcgcct ttcccaagat ttcctcggaa agaccgttgg agtagacatc
    30061 cgccgtatcg aatagattca ccccggcgtc caagcaaaga ttgaccatac gggtagcctc
    30121 ttccaccttg gtatgtcccc aaccttcaaa accattcgtg ccaccaaaag tagccgtacc
    30181 taaacaaagt gccggaacgt ataatccgga acctcctagt tgtctgtatt ccataaaaaa
    30241 ctatatctat tatttgatga aggaaatgaa aatacaaatg taacaaataa agtgtatctt
    30301 tgtcattaaa agaagataat aggtataagt atgattaagg cagtattttt tgacattgac
    30361 ggtacgttgg taagtttcaa gacgcataaa ctaccggact ccacggtccg ggccttggac
    30421 ctgttgcgag aaaagggaat caaggttttc atcgctaccg gccgccagtt gcaatctatc
    30481 aataacctcg ggacgcaaga gttcgatggc tatgttacct tgaacggagg atattgcttg
    30541 gccggaaaag ataaggttat ctataaacat aatatcccgg cgggggatat agaggcgttg
    30601 atccgctatc aagagaatga ggaggcgttc ccgtgcgcct tggtggagga agatgggatt
    30661 taccagaact acgtggatga ttctgtgcga cagctttacg acatgctaga cttccctcat
    30721 cctcccttgc gtcctttgcg tggcaacggg ggtaaggaag tataccagct gatagccttt
    30781 ttctctcccg gccatgaaga acgtatcatg tccgtcttgc cgcattgcga ggctactcgc
    30841 tggaacccgc tatttgcgga tgtcgtgccg cgggggagca gtaaggcggt agggatcgat
    30901 aagatcatcg agtattacgg gatctcgctc cacgagacga tggcttttgg cgatggaggc
    30961 aacgatatgg ccatgctttg ccacgccggg atcggggtag ccatgggtaa cgccggcgac
    31021 gaggtgaaag aggcggcgga ttacgtgacc gactccgtag atgacgatgg tgtcatgaac
    31081 gctttaagac atttcgatgt tatataaata aacagtttaa taacgctaaa tcacaaacgc
    31141 tatgattgat gaattggtaa gctataatcg tgagttcgta aagaacaagg ggtatgagaa
    31201 gtatatcacg aataaatatc ccgataagaa gatcgccatc gtgtcttgca tggatacccg
    31261 gctgaccgag ttgctacccg cctccttggg catcaagaat ggagacgtga aaattataaa
    31321 gaacgcaggg gcgatcatat cccacccctt cggaagcgtt atccggagct tgatggtggc
    31381 gatttacgag cttggggttg tagaggtaat gataatcggg cataccgatt gtggagccaa
    31441 gcacatgaat agctccgaga tgatcgaaaa gatgaaagag cggggaatcc cgcaggaacg
    31501 aatagatatg atccgatatt gtggtataaa cttcgagtcg tggttgcggg gattcgagac
    31561 ctccgaggct tccgtgcacg agaccgtgga gcaaattcgg aatcatccgc tgattccgtc
    31621 ggatataacg gtaagagggt ttgtaataga ctctgttaca ggtgaattaa cgccggtgga
    31681 gtaatccccg gcgtatttag acttatttgc acaattcata aataatcgaa aaaatgaaat
    31741 attttattat gttctacaac attgtttcgg ataaaatggt tatctttgta acgaattaag
    31801 aaagaaagat cgttttagga ttatttatta actggctttc caagcgtggg aagcgtaaaa
    31861 caaaaagatt atgatgatga gagaaaatga gaaaagcctt cgtgctttag cgatgttgcg
    31921 ttatcaagca gatcgttacc agtcagctgg caatggtgcc atgagtcagc gattaaacgc
    31981 tgagatccgt cgccttatga gcgaaatgag tgtagatgcg gataagaact aaaagaccgc
    32041 gtctttttta agtaaagaat taaagtaaga aataaattag atgtcatctc ttacctccgt
    32101 tcaaaacgga atggtgagag ataggaaatg aggattacct ttggcaatac ggccgggtga
    32161 gccttttttt gtgccctttc ctttccttct ccttcgcgta tcagggaaat tacttatatt
    32221 tgtgaatgaa aaagctaaaa caataatcat ttgaacacaa aagcgatgaa aaaagcagga
    32281 ttactcttaa tgtcgctggc attaagtacg gctctttggg cggaaagtcc ggagaagaaa
    32341 ggtttggacg tgataaatag atcgaccgcc gaggcgcata tcggtttctt ggccgatgat
    32401 gatctggagg gccgtgaggc cggtttccgt ggaggccgta tagcgggaga ttatatcgtg
    32461 gcgaacttga agtctttagg tatcgatccc gtgggcgatt cctattacca tccgttcgag
    32521 gcttaccatc tggaacgcca gaaaagagga gcccgttggc aagtccaccc ggactcggtg
    32581 gccgctatca agcagaccgg tgttttccag aagctatcct tgaataatat attgggtaag
    32641 atagagggga agaacccgaa cgagatcgtg attgtcggcg ctcactatga ccatctgggt
    32701 atcgacccga tgctggatgg cgaccagatc tataacgggg cggacgataa cgcctccgga
    32761 gtctctgccg ttttgcagat agcgagggct ttccttgcca cgggccagca accggagcga
    32821 accgttatat tcgctttctg ggacggtgag gagaaagggc ttctcggatc gaaagccttc
    32881 gttcagtctt ttccagagat aaagaacgtg aaaggatatt tgaatttcga tatgatcggc
    32941 cgtaacaata acgaggcgaa gcctacccat gtggtttatt tctatacaga ggcgcaccct
    33001 gctttcggcg attggctgaa gaacgatatc aagaaataca acttgaatct ggcaccggat
    33061 tatcgtccgt gggataaccc ggtaggaggg agtgataacg gttccttcgc taagataggt
    33121 atccctatta tctggtatca taccgacggg catccggatt accatcaacc gagcgaccat
    33181 gccgaccgga ttaattggga caaggtggtg aatatcacga aggcctcgtt ccttaatatg
    33241 tggtatatgg cgaatgagaa agatttttag agattatacg tctttttcaa tagaagatat
    33301 ctaataaaag taagttaact tcatcggcga agtaagttaa cttactttgg cattttaatt
    33361 aacttacttt gctaatgaag ctggcttgct tttatattct gaaaaaacgc ctgaattact
    33421 gtgatttcat atcttaccgc agatacttag ttctacatga acttttctta agtagaagtt
    33481 gttttattta gttggcgcca aaatacctag cacattttat atcggaggca aagatatgaa
    33541 atattcatta tattgtgtta ttataattaa ataaatcttt ccttattttt atgttttaca
    33601 atataaaatt agaaatataa acggttttaa gttaaaatcg acttgagttc atgtaggact
    33661 ccgatagtta gcccattttt tatttgaact taattacgct agaactcagg agtgagtgta
    33721 tgtatgtgaa taattttaaa agacaaatgt ttcgccaaga cattgtctaa ttatttatca
    33781 ataaaaccat cagttatgtt gaaaaacttt aaacctgtca gcttaattct atgtgcgggt
    33841 gcgttatgct tctcgggaag catgtatgcc aacatcgcac ctgttgagca aggtacctct
    33901 atctcccagc aaaacgggaa agtaacaggt acagtggaag atgatttcgg cccagtgacc
    33961 ggagcgtcag ttgtcgtgaa aggcacgacc aatggtacga ttaccgatat ggacggtaat
    34021 ttcaccttgg aaggtgtcaa gaatggtgat gtaatccaaa tctcattcat tggttactcc
    34081 accatggaaa ttacgtatac cggccaaccg gtaggcgtta tcaaattagc ggaagacacc
    34141 cagaaattgg atgaggtcgt ggttacggcc ttaggcatga agcgatctga gaagtccttg
    34201 ggttatgcga tgcaagagtt gaagggagac gctttgctgg attctcgcga gagcaatatc
    34261 gccaatgcgt tgtccggtaa ggtttccggt ttgcaggtcg ttcgttctag tggtagtgta
    34321 ggcggttctt cgaagattgt acttcgtggt gcgaactctt tgacgggttc taatcagccg
    34381 ttggtagttg tagatggtac tccgatggat aacttcaccg gtggtgtaga tgatgcttgg
    34441 ggtaactccg gtacggatat gggtaacggt ctttcggata tcaatccaga agacatcgag
    34501 tctatgtctg tattgaaagg tgcttccgct gccgctcttt acggttctcg tgccggtaat
    34561 ggtgttatct tgattacgac gaaatcagga aagaagaatg atggtctggg tatcaatgtg
    34621 aactttggag ttacggcgga tactcctttt atgttgccgg aactgcaaag ttctttcgga
    34681 cagggttctg ttggtgctta caatgaccaa accaatctga gctggggtcc gaggattgaa
    34741 ggacagacta ttactacgta tgacggacgt caagtgccaa tggccgctta tgacaatatt
    34801 ggcgctttct ttggtacagg tacctctttc aatgaaggcg taagtttcca gcaagatgtg
    34861 aatggaacct ctatgttctt ttctttcaat cgccaagatg actcgggtgt aaccccagag
    34921 caaagtctga ataagacgaa tttaacgtta cgtgctacct catttttgga tgaggctaag
    34981 aaatggaagg tggatgcgaa ggtgaactat gtaaaccaaa acgcccataa tcgtccgatc
    35041 attggtataa acccatccaa cgcattttca accgtttata atttgcctcg ctctttgaat
    35101 gttcttgatt ttgagaactg tgtggatgat caagggaaaa tggtttggta tgataaaagt
    35161 aatagtccac aggagaaccc ttattgggta actcaatacc gtcagaacga cgatacgcgt
    35221 aatcgtattt taggaaatgc ttctttaaaa tatgctccta cggattggtt tgatatcgag
    35281 ctgagaggag gtactgacta ttatactacc acgactactc aaaagttata ttcaggaggt
    35341 aatacgaagc cggaaggtag ctattctgaa ggttctgaga cattctatga gaataacttt
    35401 agcttcttgg ctacggcgcg taaggatgat ttgatcagca aattgggtgg ttttgttaca
    35461 tttggtggta acatcatgca gcagaaacgt accaaaatga atgcaagtgc gggaacgttg
    35521 ttggttcctg atttgtttga tgtcaataat ggtgttgata aaccttctat tacatcttct
    35581 ttgacccagc gtaaaatgaa ctctttgtac ggatctctcc agttgaactg ggatggttgg
    35641 ttgttcttgg atgttacggc acgtaatgac tggtcatcca ctatgtcaaa agagaatcgt
    35701 tcttatttct atccttctgt tagcttatct gctgtaatct ctgatatggt acagaaaaac
    35761 ggaggaagta tgcctgattg gtttagtttc gcgaaggtgc gtgcttcttt cgctgaggta
    35821 ggtaatgatt tggatcctta tcagttatat aatgtatata caatttctaa ggatgctaat
    35881 ggtaatagta tggcttctgc cggaagtacc ttgtttgact cttcggttaa gagtgagttg
    35941 atcaagtctt gggaggttgg tgccgactta cgtttcttca ataaccgttt tggtattgat
    36001 gccgcttggt ataagacaaa tgcgaccaat cagttgctga atattccgat ggatgctttt
    36061 tccggatatg aatctcgaaa agtgaatgcg ggtaatatcc agaaccaagg tttcgaactt
    36121 tcgttgaatg gtgctattat gcagactgct agtgggttta actgggatgc gcaagctcat
    36181 ttctctttga atagaagtaa gatcttggaa ttaaccgaag gggtgactgt ctatgatatc
    36241 aagactgtgg atgtcttaca gattgccgct accgaaggtg gtaaatatgg tgatatttat
    36301 ggacagaaat ttgttcgcca caatgggcag gtcgtggtag gtgaagatgg tcttcctttg
    36361 attacgacag ataaagagtt gatcggtaat cagaacccgg attggatgct tggtctcacg
    36421 aataatttct cttataaggg ttttgatttg agtttcttga tcgacttccg tataggtggt
    36481 gagatttact cggcgacgac ttcttctttg cataagaatg gtaacgctgc cggaacggtt
    36541 gtgaatggtg atcgtgctga tttcgtggtt ccaaactcaa tcatgaaaaa aggtgatgag
    36601 tatgtgaaga atgatgtcgc tgttacgcct caaagatatt gggagcgtat cgcttcttca
    36661 ggaaactatg gtttgccgga ggtgtttacg tatgacgcta cgaatatccg tttgagaaat
    36721 attactttag gatatacgtt caataagaat ttgttgaaga aaaccccgtt ccaaaagttg
    36781 cgtctgtccg cgacttgtaa taacgtatgg atgattgttt ctcatttgcc gggtatcgat
    36841 cctgaatctg tggcagctac aaatacgaat gcggtaggat tcgagaatgg tggcgcgcct
    36901 acaaatcgtt cttatacatt taatttaact gtaggattct aatagaaagg agataatatg
    36961 aaaacgaaaa atatcattat attaggagcc ttggcggtcg cttcattgac aacggttaca
    37021 agttgtaatg actttgagga tatcaacaaa gacccgaata aggctgattt ggagcaagtg
    37081 gaaccggaat ggttcttgaa tggctccatt ggagatgctc aaatgaaccc tgaaatagca
    37141 gaacgtattt ttattttgta ttggaagcgg gctgctcgtt ttgatcgagg tagcggtttc
    37201 gcaatcggta cggataatga tgactataat agattatact tgacttcgaa ctcgtatggt
    37261 gtaggttggt tgaataaggc gaatcaagcg atagaggtcg gagaggagaa aatcaaatta
    37321 gatgtggata atgcctatcc ttattatcgg aatatcccga atatggctcg tatttggaga
    37381 gcttatttga actctgaatt gtctgataac tttggcccga taccggcgtt atctgctttt
    37441 accggtgttc ctggagaata taataaggtg gaggatatct atacctatat attgaaagag
    37501 ttgaaagagg cggtcgcttc tttggatgag agcattgata tgagtgcgat gtccaaatat
    37561 gatccgtttt ttggtggtga cataaagaaa tggaaaaagt atggaaactc tttgcgtatg
    37621 cgtctagcga tgcgtttgac tgcggtcaat ccttctttgg cgcaagctga gtttgaggat
    37681 gctgccaagg gtgagtttat cgcctctatg gatgatatcg cccaggttgc ggagaaagat
    37741 ggatgggatc cgtatacagg tgtcatgaca agaacttgga ataaccaagc gatgtctact
    37801 actttcaata atctcgtagt gggactaggc ggtgtggaat ttcctgttcc tgatgagttg
    37861 aaatccaatt tgaaagatcc ttatacttac ttaggccaga atgtcagcct gcatttccca
    37921 acaaccacaa atgatccttg tgcgggctat tttttcgatg gtatcccaca atatatcgat
    37981 cctcgtgcgc ctcagttgta tagcattccg gggtatgatg acggagtggt ttatccttct
    38041 tatataggtg ccgcttccga ggtaaaggat gagataacat tgattgcggg agattatacg
    38101 gatgtgctga ccggacaaaa agtttccgcg ccggaagtaa aacttcccat gaaatattct
    38161 tggacgaccg ttgttgccgg aaactggaac gataaggccg gtttagttgg tgactataca
    38221 agttataact acaacttccc ttctttggct gataagttcc gtcatagcac gaacaaacgt
    38281 gtatggtttg gcccgtggga aagttatttc ttgttagcgg aagctgcggt ttatggttgg
    38341 aatgttccgg gtagcgcaaa ggataattat gagaaaggta tcgccgctag ttttgaatat
    38401 aacggtgttt ccgataaact cttagaatat ttgcaatcta aggcttataa ccgtgtagga
    38461 acatctgtag ctttcgatca tacggtagag gctaaggctt atacgatcaa ctattacgat
    38521 gcatatacga aacagaataa gacaacgact tatgagtatc ctaaaaatac gatctataag
    38581 aatggtcagt ataataatga tgcattgact aagatcatta cgcagaagtt catcgctcag
    38641 aatccttggt tgcctttgga agtgtggtct gatcaccgtc gtttaggttt gccgttcttc
    38701 gagaatcaag ctgtagaggc tgcttacaat ccaactaacc aagtgttgtt aactcctgct
    38761 acttgcaagg aatgtaaagt agagttctac ccgaagcgtc ttcgttaccc ggcagttctt
    38821 caaaccaata acttggaagg gtataaccaa gctttagaaa gacttggtgg tccgaacatg
    38881 acgacaactt ctttgtggtg gaatatgaaa taatatgaat agtattttta ctgcaaaata
    38941 ataggaatcc tcacgttggg atgtatcatc attcaacgtg aggatttatg tttttaatgt
    39001 taaactttta aattttacag ttatgagaaa gttattaatg gtattgtttt tatttggaac
    39061 aattagtgtt ttttgcaatg cccaaataga tggttattat gtaaaagaca gtggtaatct
    39121 agcgcttttt gcggatggag aacctaggac tagtaattca attggtattg aagctgggaa
    39181 atcagtggaa attcgtttta ctcaaccttc tactggagat ttcttgtggc aaaaaatgag
    39241 tggtagtgac tatattcaat ttaatcccgg tgggtctgga cgttttgcgt taatttggac
    39301 acagagtgca agtaaagggg actcggctgt tttttgtgtc acagacaaga atggtgatgt
    39361 gctgacgatt actattcatg cttattagac tttataggaa ataaagatat ctacttcttg
    39421 tcttttcttg tcttttgaca actttgtatt gtaactgatt cggaaattat agagaataat
    39481 attcttacga gaaaagggcg tatcgatgta aatgtcggta cgccttcttt tttttgtggt
    39541 gatgatttgt atgggtaaac tggaactttt attggcttct gaagtgaata actaacggct
    39601 tcctgcctct tttacggttt ggttatcctt tggttaaaat ttctgtaaat caatttttta
    39661 tggatgttag taaggataac tcttattcgt tttgtctgta aggagagagt agttgcggta
    39721 tcctcaccag ttacctcttg tatatgttaa actcaaaaca tatctgccct ttttatgttt
    39781 atacaggata aatgacattt gttgacgcaa aaactaaaac attgtctaga aaaataaaca
    39841 aaaaacagta gttatgttga aaagattcag accagtcagc ttaatcctgt tggtaggggc
    39901 gcttgggttc tcgggaaact tatacgccac gcctatgtcc gggattccga gggttgacat
    39961 ttcacagcaa aacgcaaagg tgtcgggaat agttgaggat gccttaggac ccgttaccgg
    40021 ggcgtccgta atcgtgaaag gaactaccaa tggtactatg accgacttgg acggacattt
    40081 taccttggat aacgtgaaga aaggggatat catacagata tcgtttatcg gttatacctc
    40141 gcaagacatc ccgtatactg gccagtccga gattacggtt aaactcgtgg aagataccca
    40201 gaaactcgat gaggtggtgg tgaccgcctt gggtatgaaa cgggataaga aagccttggg
    40261 ttatgccatg caggagttga aaggggatga cctcttggcc tcccgtgagc cgaacttggc
    40321 gaactccctt tccggtaagg tttccggttt gcagatcgtc cgttcaagca atggcgtagg
    40381 agggtcttct aagatcgtac ttcgtggtaa caactccttg acgggtagca accagccctt
    40441 gatcgtcgta gacggtaccc cgatggataa cttcaccggt ggcgtggatg atgtatgggg
    40501 taactccgga gcggacatgg gtaacggcct ttcggatatc aacccggaag atatcgagtc
    40561 catgacggta ttgaagggtg cttccgccgc cgccctttat ggctcacgtg ccggtaacgg
    40621 cgtgatcttg atcactacca agtccggacg taagaacgag ggactcggta ttacgatcaa
    40681 cgccggtatc accgccgaga cgattttcct gaaacctgat ttacagaacg acttcggaca
    40741 aggctccgtg ggcgtttacg ataaccaatc ccgccttagc tggggaccga aagccatggg
    40801 acaaatggta accgattgga gaggcaacca aatccctctg catacttatg ataatatcga
    40861 cgcttttttc cgcaccggaa cctcctttaa cgagggtgtc agcttccagc agaacataaa
    40921 gggtacggcg gtattcgcct ccgtaaaccg ttccgacgat gctagtatca ccccacgctc
    40981 aaaactaaac aagacgaata ttaccttgcg tgccaccact ttcttggatg aggcggaaaa
    41041 gtggaaagta gatgccaagg tgaattatat caatcaaaac gcgcataacc gcccgattca
    41101 gggcgtgaat ccctcgaacg ctttcaatac gatctataac ctgcctcgtt ccttgaatat
    41161 ccgtgagttt gaggatgacg tggatgagca aggcaatatg atttggtatg atgcctccaa
    41221 gaatccgcag gagaaccctt attgggtgac ccgttatcgc cagaacgagg atacccgtaa
    41281 ccgtttgtta ggaaatatct ccttgaaata tgccccgacc gattggttcg atattgagtt
    41341 gagaggtggt acggattatt ataccacgac gaagagcgag aaagtatatg ccggtggtaa
    41401 taccagtccg agaggtctgt ataccgaggg atcggagacc ttctatgaga ataacttcag
    41461 tttcttggct acggcccgga aggataactt gatcgatcgg ctgggaggct tcgttacttt
    41521 cggtggtaac ttgatgctcc agcaacgtaa taagatgaac gcttctgccg gagagttgtt
    41581 ggtgccgaac ttgttctcgc tgaataatgg cgtgaataag ccgacggtca cttccgagtt
    41641 gatccgccgt cgtatgaatt ccttgtacgg gtcgttgcag ttgaactggg atggttatct
    41701 gttcttggat gttacggcac gtaacgattg gtcgtctacg atgtcgaaag ccaaccgctc
    41761 ttatttctat ccgtctgtca gcttgtctgc ggtgatctcc gatatgttgc cgaagattgg
    41821 cggaagcatg ccggattggt tctctttcgc taaggtacgt gcctccttcg ctgaggtagg
    41881 taacgacttg gacccgtatc aattatataa cttctactct gtaggcaagg accccaacgg
    41941 gaatacgacg gcgaaaccgg gtaaggtact ttacgactcg gatgtacgta gtgagttgat
    42001 taaatcatgg gaggccggtt tcgatatccg tttcttcaat aaccggttag gcttggatgc
    42061 cgcttggtat aagtccaacg ctacccgcca gttactggat ttaccgatgg acccgttctc
    42121 cggctatgct tcccgtaaga ttaacgcggg taacattcag aacgagggtt tggagatctc
    42181 cttgaacggt acgattctag acaatcccgc cggattgagc tggagctcta cggcgcagtt
    42241 ctccttgaac cggaataaga tcaaggaatt atacgagggc gtgaatctat atgatataaa
    42301 gacgttcgac gctatccaga tcgtagctcc ggtaggtggt tattatggtg agatctacgg
    42361 gcagaccttt atgcgtgtga ccgatgagaa tagtcctcac tatggaaaga tcgtcgtagg
    42421 tgatgatggt ttgcctttga tctctaccga gaagtcgaaa gtaggaaacc agagtccgga
    42481 ttggatgatg ggttggacca ataatttctc ttataaaggt tttaacctga gcttcttgat
    42541 agacttccgt atcggtggta gcatctattc ggcgacagcc tccaacctgt atacccgggg
    42601 taacgccgcc ggaacagtgg tgaatggtga tcgtgccgaa ttcgtggtac cgaataccgt
    42661 ggttcaacag ggtagtggtt atgcggagaa tacggtcgcc gtcactcccc agaactattg
    42721 ggagcgtatt gggtctaccg gaaattatgg tttaccagag gtttatacct atagcgccac
    42781 caatgtccgt ttgcgtaata tcacctttgg ctacgagttc aatcgacaga tgttgaagaa
    42841 aacgcctttc cagcgtgtac gtctatccgc tacttgtaac aatgtttgga tgatccatta
    42901 taacttgccg ggtatcgacc ccgagtccgt tgccgccacg aataccaacg ctaccggatt
    42961 cgagaatgga gccgcgccga ccagccgttc ctatacgttt aacgtaaccg tgggattcta
    43021 atggaataca tgataatttg aattacgata aaaatgatga agatgaaaac aagaaatata
    43081 ctttttaccg gattggtatc ggtggctgct cttctttctt cctgtaatga ctttcaggag
    43141 atcaatgagg acccgaatct tgtgggagag gataaggtga agccccaatg gttcctgaat
    43201 gcctctatca tgggagacca gatgaaccca gagatagccg agcgtatctt tatcttgtac
    43261 tgggaccgtg cttcccgttt caatagggga agtggtttta cgatcggtac ggataacaat
    43321 gattatagta cgatctactt gagtaatgat tacgccgtag gttggctgaa tcaagtgacc
    43381 aaagcgatcc agttaggaga gcagatggtt gccaatggcg aggcggatac ctatccttat
    43441 tataagaacg tgatccagat gtcccgtatc tggcgtgctt acttgaactc ggaagtagct
    43501 gacggtttcg ggccgatccc tgcgttggcc gctttctccg gtgtaccggc tgagtacgat
    43561 agtgtagaag ctatctatca atttatattg aaagagttac gggaagctga gtctgcgtta
    43621 gacccctcct tggatatgtc cgctatggct aacgaggatg ctttctatgc gggaaatgtt
    43681 acgaaatgga aaaagtacgc caactctttg cgtatgcgtt tggcgatgcg tatctcggct
    43741 gtcgatcctg ccttggcgag agcggaattt gaggatgccg cctctaagac atttatttcc
    43801 gagccaaccg atatcgcttc cgtgcaggag aaagagggtt gggatgagct gacgagcgtg
    43861 atgtctcgtc cttggaatgg gcaggcgatg tccgtgacgt ttaagaactt ggtagttggt
    43921 ttgggtggac aggaatttcc gttgccggac tccttaaaaa gccatttgaa gaatccatac
    43981 gattatcaag gtttatattt gaaccagcac ttcccgctga cgacgaatga tccgtgcgcc
    44041 ggtttctatt tcgacggtat acctcaatat gtagatcccc gtgccccgaa gttgtttagt
    44101 gtagtgggct gggatgatgg tgtggtttat tccgattata tcggtgcggc cagcgaggtg
    44161 aagccggttc acttgaagaa tccggcggat aatacccaga atatgttgat gatcgatccg
    44221 aaatatacgt ggggcacttg ggtcgccgga gaatgggacg tgaaagccgg tctggtaagt
    44281 gagctgacag gtaagaatta taattatccc tctatatcga aacaatatcg aatgagcacc
    44341 aataagcgtg tcttcttcgg cccgtgggaa agttacttct tattggcgga ggctgcggtg
    44401 aaaggctgga aagttccggg aacggctaaa tccaattatg agtctggtgt tacggctagt
    44461 tttgagtatc atggcttatt gagccaagtc ggtgattacc tatcgtctca gaaatacaac
    44521 cgtgtaggta cttccgtcgc tttcgaccat acgacagagg cgaaatcata tacgatccgt
    44581 tatacggacc cctatacgaa ggaggtaaaa agccgtacgt atgaatatcc ccataactcg
    44641 atctatcgga atggcgctta taataatgac gcccttacga agattatcac ccagaaatat
    44701 atagcgcaag ttccttggtt gccggaagag gcttggagcg atcatcgtcg tttaggtctt
    44761 cctttcttcg agaaccaagc ggtagagaag gattacaacc cattgaatca agttcctttg
    44821 acggtcgcta cctctaagga atgccgttgg gatttctacc cgaaacgtta tcgttatccg
    44881 gcgaatatcc aaacgaataa tcaagcgggt tatgcgcaag ctctccagct tttgggcggc
    44941 ccggacttga cgactactcc actttggtgg aacgctaaat agcgaacctg cttggtctgt
    45001 tttatatata ctttttcggt gtcacgcatt tatttgtgtg gcaccgtttt tttgagattt
    45061 actcaatcgt gcttagccat ttctccagtt cgtcagtcca ttgacgtttg tatacgaagt
    45121 tgtcccggaa cccaaaacta tggccgccct ttggataaat atgcaaggag gcggacacct
    45181 tgttttttag caaagcgaga taataaagca cgctattctc cgggctaacc gcctcgtcat
    45241 ccgaagccaa cgctataaag gcgggaggtg tcagtgagtt tacgtgcaat tccaaagaga
    45301 aagcttcctc ttcctcatgc gtgggattcg ctcctaatag ccgttccctc gatttaaggt
    45361 gcgttaaatg aggtagcata ctgataaccg gataaaggag tatttggaaa tctggacgtg
    45421 cgtcgtctac cccgaatatt gcggcatgcc cggcgatata accgccaatg gaggcaccca
    45481 tgacaccgac cttcgtaatc ttccactctt ccgagtaatt atggaggatg cggagacctt
    45541 ggcgaacatc gtccagagga acttccctat gtccgttcgg catccggtat ttcaatacgg
    45601 cataagtaat accttgcgcg ttaaaccatg cggccatatc acgcccctca tgtccgatcg
    45661 aaatcttgga aagtccgcca cccggacaca tcaagatcgc cttgccattc ggcttcgtcg
    45721 ccggataaac caatagggaa gggttcgata tattggatat ggcattcggg gcatcttcca
    45781 attctacgcc ggccaatcca ttactagtgg gcgctccatc cggccaaagt aggataatcc
    45841 tatttttctg ttgtattgtt tccattttct atattctgaa ttgtgtttat agtataaaac
    45901 aacgttggcc tttgattagt ttagcattca agatcttttc gaatcatcat cgtatataaa
    45961 aaagtccgga aaagacgagg aaaatcaccc tccatccttt tcggactttt atcctattac
    46021 attgaaaggt aaattattgc ataccttccg tagtcatttc cttattgatc tttttaacca
    46081 atccctgaag aacggcaccc gggcctaact cgatgaaatg agtggcaccg tcggcgatca
    46141 tgttctgtac gctttgggtc caacgtaccg gggcggttaa ctgtgcgatc aagttagtct
    46201 taattgtttc cgggcaagtc tcggctttcg tgcttacgtt ctggtaaacc gggcaagaag
    46261 gtttattgat cgtcgtagcc tcgatagcgg cagccaactc agtacgagct ggttccatca
    46321 atggagaatg gaacgctcca cctactttca acttcaaggc acgcttagcg cctgcggcca
    46381 ataacttctc gcaagcctga tcgataccgg ggatagagcc ggagattacc aattggcccg
    46441 ggcaattata gttagcgcaa accactacct cgtccttgat gctcgcgcaa atttcctcaa
    46501 ccgtcgcgtc cggcaaggct aatacggcgg ccattgtaga gggagttgcc tcgcaagcct
    46561 tttgcatagc catggcacgt ttggaaacta ataccaagcc gtcctcgaaa gacaatgctc
    46621 cggcagctac caaggcagag aattctccta atgagtgacc tgcggtcata tccggttgga
    46681 attgatcacc taatgttttc gcgagaatga cagagtgtaa gaagatcgct ggttgagtaa
    46741 ctttggtttg tctcagatcc tcgtctgttc cggcaaacat taaatccgtg atacggaaac
    46801 caaggatctc gttagccttc tcaaacatct ctttagcaag aggattatta tcgtagaggt
    46861 ctttgcccat acctacgaac tgtgccccct gaccgggaaa tacgtacgct ttcatctttc
    46921 taattttttt ctaatttcag ttttttaaga cggtgcaaag gtaataaatt tggaataatg
    46981 aggctactat tcattacaaa ttgtatcttt gcccccatag aaacgagaat attaatgact
    47041 aatattataa tatcatgaat gaattactat ttttaggaaa cttaggtaca ggcgagatcg
    47101 tgatcatcgc cattgttgtg ttattgcttt tcggtggtaa gaaaattcct gagctgatga
    47161 aaggtatcgg taagggcgtg aagaatttca aggacggtgt aaaaggattg gaagacgata
    47221 tcaaattaga cgatacggaa aagaagtaaa ggaagatgca acaagaagaa atgtcattct
    47281 gggatcacct agaagaactt cgttggactt tatttcgttc tattttagcg ctctttgttt
    47341 ttgctatagc cggattctcg gtaatgccgt ggctgttcga taatgtcgtg atggccccgt
    47401 gtagctccga tttcatcgtc tatcgggaaa tgtgtaagat tagttctcat ttttcttttc
    47461 tcccggactt ttgtaatgat actttccatg tgaacattgt caatatcaag ctggcttccc
    47521 agttcttcac gcatatgaca agttctttct ggttggcgtt attattgact ttcccctatt
    47581 tgatgtggga gatctggaag ttcgtaagtc cggctcttta cgaaaatgag aagaaaaatg
    47641 tacgttgggt attcttgttc ggaacgataa tgttctttat cggatgctca gtgggttatt
    47701 tcttggtgtt cccgatgaca ctacgtttct tggcgactta cgagttgagt gccgccatta
    47761 cggaacaggt atcccttgat tcttacatgg ataacttctt gatgttgata ttcgtgatgg
    47821 gaatcgtatt tgagatgcca ttggtatctt ggctattatc tcagataggg ctgctaaacc
    47881 gctcgttctt tcataaatac agacggcatg ctgttgtcgg cttgttagtt ggtgcggcgt
    47941 tcatcactcc aagtagtgat ccgtttacgt taagtatcgt attcttaccg ctctacggtt
    48001 tgtatgagtt gagtgcgttc ttcgtgaaaa aagccccaaa ggaagaagac gaggagaatg
    48061 aggaagataa taatgaggaa taaatcccga aagttataat aatgtaatat aaaaaagacg
    48121 taactctgtt taagggctac gtcttttttt attatttcaa taaaggtaac cggtccagca
    48181 tattccttag cttgatggct atacgaggca tcggctcggc taccgtaaga cctaccagat
    48241 catacttgga tgctatattg ttgataacac gtacgacctc gtctattttc atcccgttag
    48301 gctctacgcc gactcccgct atcatatccg ccggatcgat tacgtccata tcgaagtgaa
    48361 cgacaacttt ggatgcgccc gtccctttta accacttgag gatggaggaa ctatccttcg
    48421 ccacctcctc tggtgataaa ccttttatac ctaagttctt ctgccgttct ttcatgccct
    48481 catcccacga gcgtaaacct acgattaagg tattcgagac cttgaacttt cccggtaata
    48541 attgaagaat ctcttcatca cccatcccta gacaggccgt aagggccatc gcatgatatc
    48601 ccttatactc gtcatacggc aagtttatat ccggatgtgc gtctatccag acaatggcta
    48661 tatcatccgg atatttagca gccagatagg tgaagggtac gacacttacc gaacattcgc
    48721 cccctaaggt gacaatcttt tctggagcgt tttcgtgcag taattcgagg gctgcttttg
    48781 tttgtttcag aataaccttg cgggcgctga tccctagatc cgtttctcta tcgtttatat
    48841 ctagtgagat gggtacttcc acggttttct ggggacttgg gggagcgagg atattgagta
    48901 attgagctcc taggtaatac cctctggaag cgtcgtccgc aggaaggtcg ggcatccaat
    48961 gattcacgat cccaccttgc cattggggat agatcaaacg aagtgtcgat gttttatctt
    49021 ccatgttatc gtagtttttg tacaaagtta aaggattcca ccgaattctc gtcttgatga
    49081 aaaaagattt tctccttgat gaaaatagat tctcatcata atgaaaaaag attttcaccc
    49141 cgatgaaaat agaaagtttt ccccgtaaac tgtttctctt tcgaaataat ttatgtatgt
    49201 ttgctcaaac tcaaaacgaa ttgcataaca tgaagcacat gtctatattg gcggtctctt
    49261 tgctggcact cgtggcctgc acgcctgaaa agaaacagga ggcggattac tcgcagtatg
    49321 tgaaccccat gatcggtacg gattttaccg gcaataccta cccgggagcc caagttcctt
    49381 ttggtatggt acaattgagc ccggataacg gtttgccggg ttgggatcgc atctcggggt
    49441 atttctatcc ggatacgacg atcgccggct ttagccatac gcacctttcc ggtacggggg
    49501 caggcgattt atacgatatc tcttttatgc ccgtgacccg tccttataaa gaggccccgg
    49561 cgccgttagg aatctattcc acgttctcgc ataatgacga ggcggcttcc gcaggatatt
    49621 accgggtatt gctgaaggat tataacatta acgtggagct tacggctact gagcgttgcg
    49681 gtatccagcg gtataccttc ccggaggccg aggcttcggt attcttgaac ttgaagaagg
    49741 cgatgaattg ggactttacc ttggattcca agatcgaggt ggtagactct acgacgatcc
    49801 gtggataccg cctatcccaa ggctggtctc ccttgcagca tgtttatttc gagacccgtt
    49861 tctctaagcc tttcgtggct tgtcatatgg atacgacttc tatcgtgacc aaggaaaaag
    49921 gttggatcgg tacggcctat gtggcccgtt tcgatttcaa tacgaagaag gatgaggaaa
    49981 tccttgtcac gaccggaatc tctggcgtca gcatggaggg agcgggaaag aatttgcgtg
    50041 cggaagcccc gaaggatgat ttcgattact atcaagcgca ggctagcgcg aattggaacc
    50101 gacagctttc caagattgag gtgaagagcc ggaatacgga cgatatggtg aaattctata
    50161 cggccttgta tcattccatg atcgccccga cgatctatag cgacgtggat ggttcttatt
    50221 acggcccgga tcagcaaatc cataaagcgg acggatggac gaattactct actttctctt
    50281 tatgggatac ctaccgtgcc tcccatccgt tgtttacgta tacggagccg gaacgggcga
    50341 atgatatgat caagggtttc ttgaagttct atgagcagaa cggggctttg cctttatgga
    50401 acctttatgg ctgggaaacg aatatgatga tcggttatca tgcggtgccc gttatcgtag
    50461 acgcttatct gaaaggtatc ggtgatttca atgccgagaa agcgctggag gcttgtatag
    50521 cgacagccaa ccgggatgac tatcggggta tcggcgatta taagaagttg ggctacgtac
    50581 cggcttatag cgatccgaaa aaatgggaga actggtcttt atcgaagacc ttggagtatg
    50641 cctacgatga ttattgcatc gctaagatgg ctgagaagat gggtaagaaa gagatcgccg
    50701 acgaattctt taaacgttca cagaattatc ataatgtgta caatccggca acttccttta
    50761 tgcagcctcg tgatgagaaa ggaaactttg ccgctaattt cagccccgat gattatacgg
    50821 aagatatttg cgagagcaat ggttggcaat atttctggtc cgtgccgcaa gatctggacg
    50881 gtttgatcgg attggtagga agtaaggaac gtttcgccga gaaattggat agtatgttta
    50941 cctatgtccc caaatcggat gaggaattgc ctatctttag tacaggcatg attggtcaat
    51001 atgcgcatgg aaatgagccg agccatcatg tgatctactt atataataag gtcggccagc
    51061 cttggaagac ccagaaatac gtggctcagg tattacatga tttgtatctg aatgccccgg
    51121 acggtatttg tggtaatgag gactgtgggc agatgtccgc ttggtttgtg tttagcgcca
    51181 tgggattcta cccggttgat ccgatcagtg gccaatatga gatcggctcc ccgttgttcc
    51241 cggaagtgaa gatgcatgta ggtaatggca agacctttac ggttttggct cccgaggtct
    51301 ctgcggagaa tatttatatc caatccgtga agctgaacgg acaaccttat gataagagtt
    51361 atatcaccca cgagcaaatc atgagcgggg cgacattgga gttcgtcatg ggcagccagc
    51421 cgggaccggt atggtatacg aacgaatgaa atagctctct atgatataat gaagagaagt
    51481 gccgtggtca tatcgccacg gcactttttt taatccggtt catgcgaatc tttcccataa
    51541 gccttgacaa tatcctttac gatgtaccag agtacgaaca cgaccatcat gcttccgatc
    51601 aatatctttc ccactcttat gatagaatcg atgtattctt ccataatgtt attatttaag
    51661 agattaccgt tcgaagtaaa tgtacggata aaaatcggga aataagtcta tgtctctaag
    51721 ataattcaga tatttgttct atttttgaac attgtataaa tgattaaata taatagcatg
    51781 ttaaaacaaa tgatagcctt gacggctttg atggtgtcat ccattgcttt tgcgcaagac
    51841 cgggagtatg taatcgtggt acatggtggt gcgggggcga tggccggatt ggaggaagat
    51901 ccggttaagt cggctcaata ttacgccgca ttggactccg ctttaatgat tggagataag
    51961 gtcctttctg cgggaggcga ggggccggaa gcggtgatgg ccgtaatcaa ttacttcgag
    52021 ggaaatccgt tgtttaacgc cggaattggt gctacctgta cggcggaggg aacttttgag
    52081 ttggacgctt ccatcatgga aggcaaggat ttaagcgcag gcgctgtagc tggcttaaaa
    52141 cacgtgaagc atccgatcaa tgccgcctat gccgtaaaga caaaatctcc gcatgtcatg
    52201 ctgagcggag ccggtgctga ggagttcgcc aaggaacaag gcttggaaat ggtagaagac
    52261 aatatgtatt tcgctacgcc caagacgatg gagtggatcg agaagttaaa gcaagaaagt
    52321 aagaagaacg gtacggtagg ctgtgtcgtt ctggataagc aaggaaactt aacggccggg
    52381 accagtaccg gcggtatgtt caagaaacgt tgggggcgta tcggtgattc gcccgtgatc
    52441 ggggcgggaa cgtatgcgga taataacagt tgcgccgtct cctgtacggg gcatggcgag
    52501 tattttatcc gtcatgcggt agcgttcgat gtgtgtgccc gctataaata ccttaaggaa
    52561 agcgtagaga aagcggcgga ttatatcatc catacggaat tgaatacgaa cgccggcaac
    52621 ggcggcttga tcgccgtgga taaactagga aatatcgcca tgccttataa cagtggcggt
    52681 atgttccgcg gattcttgta taaggagaaa ggtcgtccgg aaattaagaa gggctgcggt
    52741 atcggaaaga agatcgttgt ggtaggggaa aagtagtttt ttgtatcttt acgccaaatt
    52801 caggatagaa tggcgaaaac aaaaaccgta tatgtctgct ctaactgtgg cgctgattcc
    52861 ccgaaatggc tgggtaaatg cccgaattgt ggggagtgga acacctatgt agaggagatc
    52921 gtaacaaagg agcttgccgt gaagcggcca gttcccggta ttatggaggg caataagatc
    52981 cgtccggtgt tattgcgtga tataacgacg gaagaggagg cccgtatcga tttaaaagat
    53041 gatgaattaa atagggtcct cggcggaggc ttggtgaaag gctctttggt cttgatcggg
    53101 ggagagccgg gaattggaaa atccaccttg gtcttgcaaa ccgtgttggg cttgacaggc
    53161 ttgaaaaccc tatatgtctc gggcgaggag agcagtcgcc agttgaaact ccgggcggac
    53221 cgattatcgc atgataatcc gaactgtttc atcctatgcg agacgcatct ggaacagatt
    53281 tttacgcaag cggccaatat ccagccggac ttgatgatca tagattccat acaaaccatc
    53341 tttacggaag ttgtggaatc ttcccccggc agtgtttccc aagtacgtga gtgtagtgcc
    53401 gctatcttga aatacgccaa ggaaagcggt gtaccggtct tattgatcgg ccatatcaat
    53461 aaggaaggca gtatcgccgg tccgaaggta ttggagcata tcgtggatac ggtgttgcag
    53521 tttgagggcg atcagcatta tatgtatcgt atcttgcgga gcatcaagaa ccgtttcggc
    53581 agtacggcgg aactagggat ttacgagatg cgccagaacg ggcttcgtga ggtcagcaat
    53641 ccatccgagt tattattaac ccagaatcat gagggactga gcggtgtcgc catcgccgcc
    53701 gctatcgagg gggtacgtcc tttcttgatc gagacgcaag ccttggtcag ctcggcggtt
    53761 tacggtacgc cgcaacgtag cgccaccgga ttcgatttac gccgaatgaa tatgttattg
    53821 gcggtattgg agaaaagggc gggttttaag ttgatccaga aagatgtttt cctgaatatc
    53881 gccggaggtt tgaaagtgaa tgatccggct atcgatttgg cggtaatcag ctccatcctt
    53941 tcctctagct tggatatcag catcgagccg ggtgtttgta tggctggaga ggtaggcttg
    54001 tccggagaga tccgtccggt caaccgtatt gagcaacgta tcttggaggc ggagaagctg
    54061 ggtttctccc ggattatcat tccgcataat aatctaaaag gtttcgatac ggcgaaaagt
    54121 aagatccaaa tcgtacaggt aaagaaagtg gaggaagcct ttcggcaact attcggttaa
    54181 tatataataa acaatgataa aagaattaca actccggata ttgccggaag aggctgttaa
    54241 tgagcaatcg ctaaggcaag tagtagcccg tgagacgggt gaggctccga aaaatatccg
    54301 agccgtacgt gtattgaaac gttcgataga cgcacgccag cgaacgatat ttgtcaacgt
    54361 gaaactgcgt gttttcatga acgagatgcc cagcgagccg gaatatcaat cgatagagta
    54421 taaagatgtc tcggcaggga aacctgtgat cgtcgtagga gccggtccgg gaggtctgtt
    54481 cgctgccttg cgcttgatag agttaggttt gcgccccatc atcgtcgagc gaggtaagga
    54541 cgtgcgggaa cgcaagaaag atatcgcctt gatcagtcgt gagcataagg tgaacggaga
    54601 atcaaattat agtttcggtg agggcggtgc cggcgcttat tctgatggaa agctgtatac
    54661 ccgtagcaag aaaagaggct cggtagataa gatactgaat atcttttgcc agtttggggc
    54721 cagtccctct atcttggcgg atgcccatcc gcatatcgga acggataagc tcccccgtgt
    54781 gatcgagaat atccgggagc aaatcaagcg atgcggaggt gaggtacatt tcgagacccg
    54841 tatggatgct tttatcatga aagagaacga ggtgatcggc atcgagacga atacgggaaa
    54901 gagcttttac gggcctgtta tcttagctac cggccattcc gcccgtgatg tctataacta
    54961 tttatacgaa cgccagatcc agatcgaggc gaaagggatc gcggtcggtg ttcgtctgga
    55021 acatcctcag gaattgatcg accaaatcca gtatcatcgg aaagaaggtc gtgggaaata
    55081 tcttcctgcg gcagagtata gttttgtgac gcaagcgaat aaccggggcg tctattcctt
    55141 ctgtatgtgt ccgggaggtt tcgtggttcc tgcggcgagc ggacctaagc aggtcgtggt
    55201 aaatggaatg tcgccttcca accggggttc ccgctggtct aactcaggga tggtggtaga
    55261 gattcgtccg gaagattatt ccgaactggt agggcaggag gagctttatc ttcggaatgg
    55321 cgagaaggtg gatgcggatt ccccattagc gttgatggcc tttcaggaac gtctggaaga
    55381 ggtttgctgg ttaaacggag gcatgaagca aacggctccc gcccagcgca tggatgattt
    55441 catgcggaag aagaactctt tcgatttacc ggtttcctcg tatacgccgg gtctgctggc
    55501 ctctccgttg catttttgga tgccggaatt cgtgaccagt cgcctgcggg aaggtttccg
    55561 ttatttcggt aaggtctcta gaggcttctt gaccaacgag gcaaccatga tcggcgtaga
    55621 gacccgtaca tccgctccgg ttcgtatcct ccgtgatcgg gatacctatc aacacgtcac
    55681 ggtaaaaggt cttttccctt gcggtgaggg agcggggtat gcgggaggaa tcgtatccgc
    55741 cgccatcgac ggggaacgtt gtgcggaagg agtgtataat ttagaatcca ataaataaga
    55801 aaaatgaaaa gtggtatgaa aataggaata tccctttgtc tgggagttct tatgtgtttg
    55861 aatgcgggtt gtacgggaaa gaagtctgcc gtggaagagc cggaattaac gtacagtaat
    55921 cctttgtcgg tccagtttgg cgatccatac gtattgttgg cctcggacgg acgttattat
    55981 atgtatggta ccggtgccgg ggctgtagac ggtttttgcg cctattcttc cgatgatttg
    56041 atccattgga agtcggaagg gcaggtttat cggggcaata cgcccgattc ttgggcaatc
    56101 gctaatttct gggcgccgga agtgtacgag cgtgacggga agttctatat gttcttcagc
    56161 gcggattggc ggaagaatcc gaccaacgag gaggaaaatt tccgtatcgg cgtagctgtg
    56221 tcggataagc cgaccggacc atttaaggaa ttggccgatg ctcctttgtt cgatccggga
    56281 tatcctgtaa tcgacggaaa cttgatcgag gatgaggaag gccgtaccta tctctattat
    56341 tcccgttgtt gctataagca tccggtagaa agcgagatcg ccgatgaggc aaagaagaaa
    56401 ggcatgttcg actccgttga ggaaagctgg atttacgggg tggaggtcgc tcaggatctt
    56461 acgcacgtaa ttggggaacc cgtacttctg ctgcgtccac ccgtaaaatt ggatgatgcg
    56521 caaagtgaat gggaaagtcg ctcggttacc aaaggggagg tcggacgtcg ttggacggaa
    56581 ggctctttca tgctacgtca caacggcttg tattatatga tgtattccgc taattatttt
    56641 ggcggggcaa attatgcggt gggatatgcc gtgtccgaac atccgttagg accgtttgag
    56701 aaggcatcta ataatccggt gctggagaag aacgtggaaa aaggcggtat cgtcacgggt
    56761 accggacata atagcgttac ttggtcgaag gacggaaaac aaatgtattg cgtttatcac
    56821 gggcgtaccc agaagacagg ggatgagcgg gtcgtattca tcgataaaat gcgaatcgat
    56881 gagaatggcc ttctagtcgt ggaaggccct accaccgatc cgcaatctat tcaatagtta
    56941 tttatctctt ccagcaacgc cactcgttcc aatgagaacg tagtgtcgtt gcgttggata
    57001 tattccaata gctctttcgc tcttgcccgg agttttttac cttgcgcctc cggcaaaagg
    57061 aaactttctt ccagcaaggt cttggtcgcc agttccatgc gttggaggcc acacgagtca
    57121 tcaccgtcca gataagtgcg gatgccgtcg ataggcgtgt tcagcaagaa atcgttatcc
    57181 agttttaagg atgtgtagac ggattggatt aactcggggt tcttgcgtgc cccatcgttg
    57241 gaattacgat tgaagatgat ctgggcgatc actttgccca gttcctcgat ctgtaccatg
    57301 atgaaatctc tctttaacat aggagtggtg aattattcga tcgttatact ttggatgcgg
    57361 atgtctttct tcggacggtc attctggtct ttcggctggg tggcgatctg atccagaacg
    57421 tcgaacccct ccgtcagctc cccgaagatc gtataagtgc cgtccagatg atggcaaccg
    57481 cctacggtgg tataagcctt ccgttgctcg tccgtaaata gcaaatgccc gggagttgct
    57541 tgaataacgg agtctatctg ggcgttgatc attctcaatc gcttctggta ttcccgtttg
    57601 ttactcatct ttatcatatt caactcggca cggaccggtg cgtaaaactc cttcagggcc
    57661 ttttgccggg ccggatagtt ggcggtacgc tctaacgtat ccagttcggt ttccctatag
    57721 accttcccct gcacgataaa gaattgcgac atgtccgatt tcttttgcgg gttgacatcg
    57781 tccggttggc ggggagcagc caaggctcct ttcttatgga aatatttctc gttgatctcg
    57841 ggcaggatct cggcggaagg atcgccaaag ccgcatttgg caccggcggg agcgttcttg
    57901 gaatccgggg ctcctccttg gatcataaac tccggcagga cacgggtgaa taaggtcccg
    57961 ttgaaatccc cccgtttcgc ccgttcgata aaagtacggg tgtgattagg cacatcatcg
    58021 tacaggatgg ccttcatagt acctacattg gttttaataa ctaccgtttt tccagcttct
    58081 tgcgccgagg tggctaccac gcaaaggaac aatgctgata aaatgtaata tatctttttc
    58141 atgagatttt aatttaaaag gtaaatatag gtgttatgtt gtaaaacaca aagtaaatgc
    58201 ctaacttcgc gtctttatta ataggtaata agatttttaa agattttagc atggattgga
    58261 taaacgattt attatgggga gaaggtatcg ggcattctat ccttttacta tctttcgtga
    58321 ttgccgccgg cattcagttg ggaaagataa aggtgtttgg gatttcgctt gggattacct
    58381 tggtgttgtt tgtaggtatt attttagggc attttgggtt tacggttaac cacaatgtga
    58441 ttcatttctt taaggaattt ggattgatct tatttgttta ttcggtaggt atgcaagtcg
    58501 ggccgggttt cttctcgtct tttaggcagg ggggaatcac gttgaatatg ctagcctgtg
    58561 gaattgtctt ccttggcgtg gctacggctt tggtattgca tttcgtgaca ggtattccga
    58621 tgcctacgat ggtgggtatt ttatcggggg cggtgacgaa tacccccgga ttaggtgcgg
    58681 ctcagcaggc ttattccgat atgtacgggg tttctgataa tacgatcgcc ttgggttacg
    58741 ccgtggctta tccgctgggc gtgatcggta ttattctttc gatcattttc gtacgttacg
    58801 tattccgtgt gaatttcgat aaggagaatg acgatttgaa taaggaggat gcctcgcata
    58861 cgaatgaggc gaaaccgatc tcgctggtcg taaagaaccc tgcggttttc ggtaagacgg
    58921 taggggagtt atccggtttg atggatcatc tggatttcgt gatttcccgt gtatggcgta
    58981 atgataacaa gcagatcgag atcgcttccg ccggtacgat cttgaatgag gatgataaga
    59041 ttttcgtgat cacgacagat caagatgccg agtccgtaaa gacattcatc ggcgaggaga
    59101 tcgatatgga gcgcaagcaa tggattcgta tggagagcca gtttatcaac cgccgtatct
    59161 tgatcacgaa accggagttg aacggcaaga agctggggca gttgaaactg cgtaaattat
    59221 atggcatcaa tatcacccgt atcaaccgtg cgggcgtgga cttggtcgct acgccgggcc
    59281 tgacgttgca agtgggtgac cgtgtgaatg tggtgggtac cgaaaccgct gtctcgaatg
    59341 tggagaaggt attgggtaac tccatgaagc gcttgaacga gccgaatttg atcacgatct
    59401 ttatcggcat tgccctcggt attgttttgg gtagtattcc tattacgttc ccgggcattc
    59461 cgcaaccggt taagttaggt ttggcgggag gtccgctgat cgtggcgatc ttgattagcc
    59521 gttttggtta ccgttataag ctggttacct atacgaccca gagcgctaac ttgatgttgc
    59581 gtgagatcgg tatcaccctc ttcctcgctt gcgtgggtat cagcgccggc gatggttttg
    59641 tggatacgat cgtgaacaac ggcggattcg cttggatcgg ttacggtttc attatcacga
    59701 cggttccttt actgatcatc ggttgtgtag gccgctattt ctataagatc aattatttca
    59761 ccttaatggg cttgatcgcc ggtagtacga cggatccgcc cgctttggct tactcgaacg
    59821 ctacggctgg aaacgacgct ccttccgtag gttacgcaac ggtataccca ttgaccatgt
    59881 ttttgcgggt gcttacggcg caattattga tcttgttctt cgcttgatgc ggtagttata
    59941 atggtgccgt cttacacgta taccggcatt gcctcacacg tatatcgacg ttggcctatg
    60001 cgaacgtagg cgtgaggcga tgtcggtata cgtgctggat ggagttgacg ccggggaaaa
    60061 taaaaagcat agatgtatta aatttaccag tttaaaaggc aatgttattc gtagcattgc
    60121 cttttttgtt agttttgtgg gagtataatc taatttaata tcgtggaaag aatgagtgta
    60181 gagaagaaaa acgcttatat cggagtggat ttagggggga cgaatatgcg tgccggccgt
    60241 atcgcagggg atcgattagt ggctcagggg aacgccccga ctccccagga cgccgcggat
    60301 tgcggggaga cattggaggc tttgatagag gtgatccgtt ccgtgtggga cgagggcgtg
    60361 gtagctatcg gaatcggtgt gccgagcgtg gtggatcgtg agaaggggat cgtatataac
    60421 gtggtgaata tcccgcattg ggaggaggta catttgaagg agatcttgga ggctcgcttc
    60481 tccgtgccgg tttatgtgga taacgacgcg aattgcttcg ctcttggtga gcgtatcttt
    60541 ggcgacggaa agacggttga taacttcgtg ggcctcacct tgggtacggg cttggggggg
    60601 ggagttatcc agaaaggcaa gctgctggcc gacgctaatt gtggctcggg agaatttggc
    60661 atgattccct accaaggaca gatcttggaa tatttctgta gcggttccta tttcatgaac
    60721 gtatggggcg tggatgggaa ggagatgtac acccgtgcga tgcggaagga cgagcaggcg
    60781 ctggaggctt accggcagtt gggcgtacat gtggccgccg ctatcaagat cgtcgtatta
    60841 acggtagatc cagagatgat cgtcttcgga ggctcggtga ccgccgccca tgagttgttt
    60901 gaggagagca tgtatgagga cttgaaggat ttcgcttatc cgaactctat caagaacttg
    60961 aagatacgtt tctctaagct ggagaatccg gggctattcg gtgccgcttc cctttgttat
    61021 taaataaaga cggataattt atagtttact taaatcttat tcataccatg agacatgtat
    61081 tttgtaggaa gatcgttttc cttttggccg ctttactggt tgtatgtggc atgtcggccc
    61141 gtaagccgat caagacgtta ttaataacgg ggcagaataa ccataattgg caggtgagcc
    61201 atgtggtgct taaacagata ttggagaact cgggacgctt ctccgtggat ttcgcggtct
    61261 ctccggaggc ggggaaggat atgtccggct ttgtcttgga tttcagtcct tacgagctgg
    61321 tggtgctgga ttataatggg gatgcttggc cggaagagac aaaccgtcgt ttcttggaat
    61381 atgtgcgagg aggtggtggt gtcgtggtct atcatgccgc tgataacgcc ttcgtgaact
    61441 ggccggaata caataagatt tgtgccttgg gtggttggga gaaccgggat gagaaagcgg
    61501 gaccctatgt atattggagc gatggtaagt tgataaagga tagctcggcg ggcgtgggtg
    61561 gctctcatgg caagcaacat gagtatgtgc tgaatgcccg gaaccatgat catccgatca
    61621 tgaaggggct gccgaataaa tggaaacatg cgcaggatga gttatatgat cgtatgcgtg
    61681 gcccgggaaa tataaaggat tgcttgtata ccgcttattc ggacaaggag accggaggct
    61741 ccggccgtga ggagccgttg atctttacgg ttgattatgg gaatgcccgt atattccata
    61801 cgatgctagg gcatgcgggg gaaacggtag agaattgtcc ggctatgcaa tgcgccggct
    61861 tccagatcac cttgttaaga ggtgcggaat gggccgctac cggcaaggta acccaaaagg
    61921 ttcccactga tttcccgacg gaaaaacaag tatctaatcg gagtaattat aagcggtgat
    61981 acttggttta ttagaatgcc cattgtaagc tccttatgat gggcattcta gcaagctaac
    62041 aatgggcatt ctaaggagct tacgatgggc atcgtgctat tttgctgaat cctcgtgcga
    62101 tagatagccg tcgcttaatg tgaatcgggg atcttgatcc gccagaaagc ggatggccgt
    62161 gaggcttttc tcttgaggga aaggtaattt ctcaataagt tctttcacgg ggatagggga
    62221 ttccccggcc aataccttta cgagactttc ccggatagcg ctgaattccc aattcataag
    62281 ctgtgattca tgcttcgata ggcatacgtc gcaacagcca caaggggcgg aatcttcctc
    62341 gccgaaatag gataggagca tgcggctacg gcatacccgc tcctcgttga tatattccag
    62401 caccttctcg atccgtttcc cgaaacgctc cttgcgttcc tcatacgccg agcggggtat
    62461 ggaaagatac cgctgttcct cccgggtctg ggtatagata atcaacgggg ttttcttatg
    62521 cgggatgtag tttacgatcc ggtatctgga taaacctacc aaggtctcat acacctcgtg
    62581 aggcgttact ctcgcacggg tagcgattac gctctcatct atataaacat aatccgcgaa
    62641 taacccggtg taagaacgca agatcgtctg aatcacctca tccgttcgct tgttctcact
    62701 taaatacctg taaagctcgt cacgggtagc cgtgaacatc aggcgagaag cgttgtccac
    62761 ctcctccgta tactcgatat agcccgatag cccaaggatc ttcaaggcat gatgtgcttg
    62821 caataaagag aacttataag cggaacaaaa atccgttaac gagaaatcgt gtaccgtatc
    62881 tagcccgtac cctacggcga tctggtaata attacccaac gcctcataga cccggtagat
    62941 aaactccttg tccggaaact catccgccag ccgtttcttt agcttggcgc tatccgtgga
    63001 ggaacaaaga gccacggcga aggctttctt ctcatcacgt cccccgcgtc cggcctcttg
    63061 ataatattcc tccaacgatc ccggcatatc catatgcacg accaatcgca cgtccggctt
    63121 atcgataccc ataccaaaag cgttggtcga tacgattacc cggcactcgt tgtttttcca
    63181 acgggcctga cgcagttctt tctcgtcacg gtttaacccg gcatggaaga aatcggcgga
    63241 gatacccgcc tgttgcagca tgagggcgat ctccttggtg cgtttccggt tgcggacata
    63301 tacgatggcc gtacccggaa cttttcccaa tatataaacg agtgtattta acttatcctc
    63361 cgtcttccgg acaatataag ccagattttt gcgggcgaag ctcttttgaa atacgttctt
    63421 ctccttgaac cgcagacgct cttgtatgtc attcaccact tccggggtag ccgtggcggt
    63481 caaggctaat accggaacac ccggcaataa gtcccggatc tcagcgatat tgaggtaaga
    63541 aggacggaaa tcatatcccc attgcgagat acagtgactc tcgtcgatta ccagcagaca
    63601 aacctgcatg gcctccatct tgacccggaa aatatccgta ctaagccgct ccggggagac
    63661 atataagaac ttataccccc cgaagatgca attctccagt tgcgtgatga tctcttgccg
    63721 gctcatgccc gaataaacgg ccgtagcctt gatgccgacc cggcgtaagt tctccacttg
    63781 gtctttcatc aaggcgatca agggagtgac gacgatgcaa atcccctcca tcgccaatgc
    63841 cggcacctga aaggtgatgg atttaccacc acccgtaggc atcagcccaa gcgtatcttt
    63901 tccggcacag acggaatgga taatatcctc ctgcaagggg cgaaaagcag ggtatcccca
    63961 atacttctct aatatcttat ggtagacgtc cacctgtcct cctcatatat cgtcgggttt
    64021 gatgtctttg atcatcagct ggatagaggt gttgccgttg taggtgttct cctccaccgt
    64081 gtaacagatg ttgaaaggct tcataccctt gatatggtcg ttgtacctgt gcatgccgaa
    64141 agcgatggcg tgcatggggg tgcttgagtt tccgtcgatc aattccagct tgagatgctc
    64201 cagttcctta cccacgagct tactggtgcc gtagtccttt acgccaagcg aacagaatac
    64261 gggcttttgg ttgtccggcc cgaacggact catcttcttt aggtcgttca cgaacttctg
    64321 gttgatctct ttcaaatcca agatagcgtc gatatcgatc tgcgggatca tctgctccgg
    64381 tatgatctcc tcggatgcga tcttcaagaa acgctcggtg aatgcctcta ggttctcctc
    64441 ccgaagggaa agcccggcgg cgtaggtatg tcccccgaaa ttctccaata aatcccggca
    64501 actctctatc gccttgtaaa tatcgaagcc tgttacggaa cgtgccgatc cggtgatcaa
    64561 ctcggacgat ttggtaagaa cgaccgccgg acggtaatac ttctcggtca aacgggacgc
    64621 tacgataccg atcacgcctt tgtgccatcc cgggttatac accacgatcg ccttccggtc
    64681 atccatgttc tctacttcgt cgatgacagc gttagcctcg tcggtgatct tcttgtccaa
    64741 ttctcggcgt tcctcattat attggttgat gctctcgctc ttctcccggg cactggcgct
    64801 atccttggac agtagcagtt ccaccgcctc cttcccgttc atcatacggc cggaagcgtt
    64861 gatacgggga ccgatcttga agacgatatc actgatcgtg atctcctttc cggtcaatcc
    64921 gcagatatcg ataatccctt tcagcccgag gctggggttg ctgttcaatt gcttcagccc
    64981 gtaataggcg aggatgcggt tctctcccgt aatcgggacg atatccgagg cgatactgac
    65041 cgctgtcagc tccaacaact tctccagatc cgagaacggg aaattattgc tcttggcgaa
    65101 cgcctgcatg aacttgaatc ccactccgca acccgataaa tgctcatacg gatagataga
    65161 atccgagcgc ttggcatcca atacggcgac agcgtccggc aaagtggcgt ccggcatatg
    65221 gtggtcgcaa ataataaagt cgatgccttt ctccttggcg tactcgatct tctcgatcgc
    65281 tttgataccg caatccagcg agataaccag cgacacgccg ttctcggcgg cataatcgat
    65341 acccttgtaa gagataccgt acccctcgtc gtaccggtcc gggatataga aatccaaggt
    65401 agacgagtaa ggtcttaaat acttgaagac gagcgatacc gctgtcgttc catccacgtc
    65461 gtaatcgccg tagatcaaaa tcttttcttt attccccaag gctttgttca agcgcctcac
    65521 cgccttatcc atatccggca taaggaacgg gtcgtgcaaa tcgttcaagc tgggtttaaa
    65581 gaatttcttc gcctcttcga tcgaagtgat acctcgttga acgagcaaga gacagatcac
    65641 cgggctgaat cctaattcag ccaccaattg gtctctctta tgtaactctt cttctgatgg
    65701 ggtttgaaag ttccatttgt taatcattat atattgtttt tttctttttt gcttgcctga
    65761 tactacggat accttgtcat ccttaatcta ccgtatgaca aaggcgagat ttccgcaata
    65821 tatttcaacc cgtaaagtta gaaattaaat atggtatatc cggtatggct taaagaaaat
    65881 agtttttttg ttattatttt tttgaagtag gagaatgatt cgtacatttg cctaaatatt
    65941 ataaaataca atgacggaag atattaaaaa agcttgcgaa gtaatggccg caggcggcat
    66001 aatactttat cctacagaca ctatctgggg aattggttgc gacgctacca atgaaaaagc
    66061 cgtacaaaga gtgtacgagc taaagcgaag gacagacaat aaggctatgt tggtcttgat
    66121 ggacagcgag gctaaattgg ataggtacgt gtcggatgtt cccgatatcg cttgggattt
    66181 gattagcgtg tctgataagc cgttgaccat catttactca agtgccaaga acttggcgac
    66241 aaatctattg ggagccgatg gtagcgtggg tatccgtatc acgaacgagg agttctccaa
    66301 gaaattgtgc gagcgcttcc gtaaaccttt ggtctctact tccgccaacg taagcggcga
    66361 gccttctccc gctaatttca gcgaggtatc ggaggtgatc aaggagggtg tggattatat
    66421 cgtgagttat cgtcaggacg atatgagcaa ggccgctccg tccggcatta tcaagttagg
    66481 agccggtggg cttgtgcagg taattagata aggatgaaga aaagcgtaca agccggaaaa
    66541 tatattgtct cggattttat agcgtcgtcg gtagtctggt tattatttaa cctgatacgc
    66601 tatgaggagg tggcggtgta tgaagggttt gataccgtcg gggccttttt gctgcatatc
    66661 ccctcattga aggggcagct attgatcccg tttttctggt tcgtattata ttggttttcc
    66721 ggttattata ataaaccgtt cggtaagtcg aggcttactg agttgttctc tacccttggg
    66781 agcgtgtcga tcggtgtcgt gatcttgttt tttgccttag tgctgaatga cttgccccgt
    66841 tcttatcacg tgtattatga tatgtttttc tctttatggg gattgcagtt tgtcttgacg
    66901 tatattcccc ggttattgat tacgcaggcc gggttacgga agataaagtg cagggaatgg
    66961 gcgttgaatg tattgatgat tggggcgggg aagaaggcgg cgtgtattgc cgacgacctg
    67021 tatggtttgg gttataatat cgtcggtttt gtctccgatg gtacggagaa aaagggcggg
    67081 gtcgccggag atcgtgtgat cggtaggcta gaatctttgc cggtgatcgt agaggagaaa
    67141 aaggtggatg agctggttgt cgccttggag acggtggata ataaccgttt gatggatatc
    67201 ctgtattcgt tatattgcta taaacggccg atcaagatat tggcggataa atccagttca
    67261 ttatcgcaag taaagatcaa ggcgataaag ggcgttccgc tggtggacgt gacggataac
    67321 aacttcttgc ccatcgagca gaatgtaaag ctctttatgg ataagacgtt atctctgatt
    67381 ttcttggtgc tcttatctcc cttgttcctg tatatcgctt ggcgggtgaa gcgggattcc
    67441 cccggcccgg tgtttttcag tcaggaacgg atcggataca tgggcgagcc tttcatgatc
    67501 tataagttcc gtacgatgta cacgaacgcc gaggaggaag gcccgttgct ctcttccgag
    67561 gacgattccc gtatcactcc cttcggacgg gtgatgcgga aataccgctt ggacgagtta
    67621 ccgcagttct ggaacgtgct gaaaggggat atgtcgctag ttggcccccg tccggaacgt
    67681 aaatatttca tcgagcggat cgtgaggaaa gcccccttct actatctgct gcataacgta
    67741 cgtccgggaa tcacctcgtt gggtatggtg aaatatggat atgccggcag cgtggatgag
    67801 atgatcgagc gcttggaata tgatatatta tactatgaga atatgtcctt gattctggac
    67861 ataacgattc tcatttatac agttaaaaca gtgtttacag gtaaaggtat ttaaaatggc
    67921 aaacgaaggt ttattctata aattcttgtt gtggagggaa aagcgcatca aggagaagca
    67981 tttcatcctt attatcagtt ttatcgtggg actttgtacg gcagccgccg ccataatact
    68041 gaaacagctg atccatttca tacagcattt attgacgggc aatttcaatg ctgatggcgt
    68101 aaattacctc tatttgcttt atccggtgat cggtatcttg ttggccggat tattcgtgaa
    68161 atacatcgtg cgggatgata tcagccacgg tgtgacgaag atcttgtatg ccatctcgca
    68221 acgaaagagc cgtatcaagc cgcataatac atggacctct atcgtagcca gttccgtgac
    68281 gatcggcttt ggtggatcgg tcggggcgga ggctcctatc gtattgacgg gggcggctat
    68341 cggttctaat ctggggcggg tgttcaagat ggagcaaaag acgttgatgt tgctcgtggg
    68401 atgtggtgcc gccggagcga tcgccggtat cttcaaggcg cctatcgccg ggttggtgtt
    68461 cgttatcgag gtattgatgc tggaccttac gatgacttcc gtgcttcctt tgctgatctc
    68521 gtcggtgacg gcggctacga tgtcttatat ctttaccggc accgaggcca tgtttaagtt
    68581 ctctcagacc gaggcattcg agatcgagcg tattccttac gtgctcttgc tgggtgtttt
    68641 ttgcggattg gtatcccttt attttacccg tgtgatgaac aaggtggaag ggatgtaccg
    68701 gaagttgggt acgtattgga agaagttcat gttggg
//
LOCUS       DBMDTB010000009        59417 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_218_length_59417_cov_11.701683, whole genome shotgun sequence.
ACCESSION   DBMDTB010000009 DBMDTB010000000
VERSION     DBMDTB010000009.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 59417)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 59417)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59417
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_218_length_59417_cov_11.701683"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(193..1437)
                     /locus_tag="ACZPB4_02750"
     CDS             complement(193..1437)
                     /locus_tag="ACZPB4_02750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008771829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HIR1097177.1"
                     /translation="MEIKKKLKNPMVINFISLALLQGVNYLLPLLSFPFLFRVLGVER
                     WGLVTFGYALMQYFIMFTDFGFNLSATKYISEHKTDLGKINSYLNSTMLGRFFLCGVS
                     FAILLILITCFDKFKSESSFYLLYFGMIIGNVMFPMWFFQGMENMKYITVFNIVAKSL
                     SFLPFFIFIRKPENYIYVPICYSFGFILAGIVSIFIVYFRMGMKWYFTSIEEVSNSLK
                     DSSTYFLSRASTSLFTTSNSFLLGLICGNTAVGYYSAAEKLYQAYNQLLTPFTGVLFP
                     HIAKSRDVLFFKKVFYRITFSNFFCVTTVLLFSSYVLRFVYGTADPDILEVFRILVIA
                     CFVTIPSMLLGYPFLAAMGHPLYTNYTVMTTSMVHITGLAILYVCGMIAPITVAMMVV
                     VSETLLFLFRIWGIRRFGLFRA"
     gene            complement(1463..3280)
                     /locus_tag="ACZPB4_02755"
     CDS             complement(1463..3280)
                     /locus_tag="ACZPB4_02755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008771830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HIR1097178.1"
                     /translation="MQAIILAAGMGKRLKELTKNNTKCMIKVHNQTLIERMLKQLEAL
                     SLKRIIIVIGYKGEKVRELIGDKINNTPVLYVENNVYDKTNNIYSLYLAKNYLVEDET
                     ILLESDLIFENSILSKLINHPYPNLAVVAKYQSWMDGTVVRLDEDNNILNFISKKAFQ
                     FCQKESYYKTVNIYKFSKEFSTNKYIPFLEAYCKALGNNEYYEQVLKVISLLDRPDLK
                     ALTITTEKWYEIDDQQDLNNAEALFSEGKQALSLYGKRYGGYWRFPMLLDFCYLVNPY
                     FPNTRLKEEMKANFDTLLTEYPSGMQENAQLAARYAGISSEQIIVGNGAAELISGYMR
                     MTSKYTTGVILPTFEEYPNRLAPKQLVYYTPSNRDFSYTALDIISFFDNKAIEQLLII
                     NPDNPSGNLLSKNEIFALVEWSERKGIRLIIDESFLDFANPENKLSLLDKELLNKYPH
                     LIVIKSISKSYGVPGLRLGFLASGNKDLIRTLKKDISIWNINSFAEFYMQIFVKYSDD
                     YDKACHKFLNERERFFQNLQAVSYLRVIPSAANYFLCEVTDTYTSEELCSSLLSGNNI
                     LIKNCGTKAGFEGKQYIRIAIRNKEDNDKLIEALTSLNK"
     gene            complement(3425..4372)
                     /locus_tag="ACZPB4_02760"
     CDS             complement(3425..4372)
                     /locus_tag="ACZPB4_02760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008771831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase"
                     /protein_id="HIR1097179.1"
                     /translation="MKIISENQIKDLGITPATCVDWAKESFSIKNKAQLPAKISVHPQ
                     GNDFFTSMPCLLPQEFSRFGIKVVHRIVGGIPALGSDILLYDSNTGELLALLGGDWIT
                     AMRTGAVATLAIQTLKATDATTYSFIGLGNTARATMLCLLDSQKNTHHTVQLLKYKDQ
                     ADSFIERFGAYPNVTFSIIDNIENLISNSDVIISCITDASNLICPKNDLFKEGCLVVP
                     IHTRGFQNCDLFFDKVYGDDTDHVKGFRYFSQFKQYAELEDVLSGRTAGRENDHERIL
                     SYNIGLGLHDILFASKIYDSLSAQSPEIKIEREVSKFWI"
     gene            4496..5812
                     /locus_tag="ACZPB4_02765"
     CDS             4496..5812
                     /locus_tag="ACZPB4_02765"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose dehydrogenase family protein"
                     /protein_id="HIR1097180.1"
                     /translation="MKIAIVGTGYVGLVTGTCFAEMGTEVFCVDVDKVKIENLKKGIV
                     PIYEPGLDEMVARNSQAGRLHFMTDLKECLNEVEVLFCAVGTPPDEDGSADLKYVLEV
                     ARTVGRYMNKYILVVTKSTVPVGTAQKIKKAIKEEQALRDVSIEFDIASNPEFLKEGA
                     AIKDFMSPDRVVVGVESDRAQKLMAKLYRPFLLNNFRVIFMDVPSAEMTKYAANAMLA
                     TRISFMNDIANLCEIVGADVNMVRKGIGTDARIGSRFLYAGCGYGGSCFPKDVKALVK
                     TAANSGYQMRILEAVEAVNEEQKSILFRKLMKHFRGDIQGKRIALWGLAFKPETDDMR
                     EAPSLVLIKKLKEAGCVISAYDPVAMPEAQRRLPVGVISYGKDIYETVIDADALLLVT
                     EWKEFRMPSWSVIKKLMSTPLILDGRNIYDKTELEETGFIYHCIGR"
     gene            complement(5816..7060)
                     /locus_tag="ACZPB4_02770"
     CDS             complement(5816..7060)
                     /locus_tag="ACZPB4_02770"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HIR1097181.1"
                     /translation="MNNTALQIYALFILLILSVGCKDDWKNLNLRSGENEPFYWENNK
                     LAAQRLAKIMYNKTDSGSYERFKIVHISDSHLSSWSPSNNYELPINLRQSIQFANQQE
                     LRINAITATGDFISIDKKKKAKEYMHSFIHYLYDENHVPTFICTGNHDSNSEEEIGST
                     FFYKNEINEILFANSNYSKNRNSAENYYYSDVANPQGGTIRFIALDMLDQPASQYNTL
                     SYAYFSQKQIDWLINTALKNGMTDHHSVIILTHYPFQRRSVNNDTYLCDGDYVHSWNM
                     IPEIIEAFRTRSLLEKVYPNQFNLDPINVKADFSDRKGEFVCYLGGHIHCNAYFDVTG
                     LENESTELVPQKMILCTNQAPSEKGVVYNRVIREEDSLSSNSFCIYAVDTKEKKIYIT
                     YFGAYKPSNDCNYPEIHTISYN"
     gene            complement(7105..7260)
                     /locus_tag="ACZPB4_02775"
     CDS             complement(7105..7260)
                     /locus_tag="ACZPB4_02775"
                     /inference="COORDINATES: protein motif:HMM:NF024081.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HIR1097182.1"
                     /translation="MWQDIAVCVIGISVIGYIAYKVYRMLTKPKSSDPCCGCSGCSLK
                     KEFRMKE"
     gene            complement(7311..9800)
                     /gene="feoB"
                     /locus_tag="ACZPB4_02780"
     CDS             complement(7311..9800)
                     /gene="feoB"
                     /locus_tag="ACZPB4_02780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0015093 - ferrous iron transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HIR1097183.1"
                     /translation="MRLSELRTGDKGVIVKVMGRGAFRKRIIEMGFIRGKEVIVIQNA
                     PLKDPIHYRVMGYDVSLRRSDAALIEVVSAADFEKEQATSVQDTNRSADSFILPSGNE
                     LQAIALHKGKTINVALVGNPNCGKTSLFNFASGAHEHVGNYSGVTVDAKEGTFQQNGY
                     TFRIVDLPGTYSLSAYTPEELYVRKHLNEEQPDVVINVIDASNLERNLYLTAQLIDMD
                     VRMVIALNMYDELERHGNKFDHESLAKMIGAPIIPTVSKTGFGIEDLFNRVIKVYEEE
                     DPVIRHIHINYGESLEKGISNVRKTLKNSVDIPKSLSKRYLSIKLLEGDREIETFIKT
                     LPGAETIFQERDRNTALIEKLLQEDCETAFTNARYGFISGALRETYEQNMIKEATSTQ
                     IIDLFVTHKVLGFPIFILFMWIMFEATFRLGGYPMEWIEALVEVIGNFVRNHMSEGPL
                     KDLLVDGIIGGVGGVIVFLPNILILYMFISFMEDSGYMARAAFIMDKIMHKMGLHGKS
                     FIPLVMGFGCNVPAIMASRTIESRNSRMITMLVNPLMSCSARLPVYVLLTGAFFPKNA
                     SFVLLALYVSGILLAVIMARLFKRFLFNEEDVPFVMELPPYRMPTGKSIMIHMWEKAK
                     QYLHKMGGIILVASIIIWFLGYFPRHSESGDQFDRQIAEIENTELDSQEKTDTIEELE
                     RLKAIDHQQNSYIGRIGQTIQPILAPLGFDWKMSVSLLTGMAAKEVVVSTLSVLYTGN
                     ADDDSQALSERLKQDRNAEGNLVFTPLIAISLMLFVLIYFPCIATISAIVNESGSWKW
                     GIFVIIYTCVLAWIVSFIVYQTGNFFVGLFS"
     gene            9938..10423
                     /locus_tag="ACZPB4_02785"
     CDS             9938..10423
                     /locus_tag="ACZPB4_02785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097184.1"
                     /translation="MKLRITLFTTLLVLLSACFTGCKKELKDFSFSYSMESVDNYKLM
                     VLFDSDKTFRIEEYNYYMDNFAKKRDPKIMEGTLTDEEFASLKPILQKCNFFKMKDSY
                     GFEEETNRDLGDIMYQVSFTTEGKEKFISIRNSDTGQFSASFVKLIGFINTFLNNHKN
                     D"
     gene            10440..10850
                     /locus_tag="ACZPB4_02790"
     CDS             10440..10850
                     /locus_tag="ACZPB4_02790"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008771836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003848 -
                     2-amino-4-hydroxy-6-hydroxymethyldihydropteridine
                     diphosphokinase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HIR1097185.1"
                     /translation="MENKRNRVLLCLGSNWDKEKNMERAAEMLRAHFVFIQFSQPVYT
                     EPIDCPLSTTFLNRVAVLYSEESPARIKDVLKDIECCIGRKPEDKSCGRVPIDIDLLQ
                     WNDQILKAEDLTREYVLDGICSLLAAGENDEWCQ"
     gene            complement(10794..11807)
                     /locus_tag="ACZPB4_02795"
     CDS             complement(10794..11807)
                     /locus_tag="ACZPB4_02795"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HIR1097186.1"
                     /translation="MMKENRSDLLHTLTERLKAIDYNKLPISDYNKRYIGNLKPALSY
                     FMHIYADCLQRGLQAIQTPISDVTLIDYGGGTGFLSILAKSIGIGQVIYIDLNPSSVE
                     TIQLLKQIIGIGPDTILHGDSDVLADWCARNKVSPQLLIATDLIEHVYDLSLFFKDLI
                     HINDSMYLLFTTASTPFNPYVQQRLHKMMIGCESGSLESPNYYTLREQFITKLCPAFS
                     PKEVETWARQTRGLTYPDIQKAIEKKSLPSPEDPYNTCDPATGNWAERILPIQTYEDL
                     LAPYQFKLKVEKGFYNADRNNPVLSLICKGINALIRNSGSFGFLLAPFIILSCGKERA
                     DAI"
     gene            complement(11791..12924)
                     /locus_tag="ACZPB4_02800"
     CDS             complement(11791..12924)
                     /locus_tag="ACZPB4_02800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family protein"
                     /protein_id="HIR1097187.1"
                     /translation="MDKYLNIVSFNIPYPANYGGVIDVYYKLEALHACGVKLILHCFE
                     YERPHAPELESICDKVFYYKRRTGVIANLTWLPYNVYSRKDHRLIENLLQNDYPILFE
                     GLHSCYYMDDPRLRNRMKIFRECNIEHDYYRHLAKSGKGLVRNAFFKIEAMRFQAYQK
                     VAQYANLIIAVSTTDADYLRKQFPNQRIEFVPCFHENNRITAKPGKSDYILYHGKLSV
                     IENERAVLFLTKHVFSQLKHTCIIAGMNPTRLIREAAAPYPHIKVEANPSKERMDALI
                     HNAQIHMLITFQDTGLKLKLLNSLFAGRHTIVNHLMLAGSGLDPLCHIADTPDEMIRA
                     CEQLMALPIDKEAIDKRKQLLFPAFSNEDQGIRLYKMIYDERE"
     gene            complement(12929..14164)
                     /locus_tag="ACZPB4_02805"
     CDS             complement(12929..14164)
                     /locus_tag="ACZPB4_02805"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HIR1097188.1"
                     /translation="MNKLLIICDMFPPAFAPRMGYLCKYLTRMGWEVTVVTEYIEDNT
                     FEFLTGYADVYCVRYYKASGKISKHIEWMWVMFLDILFGYKDMKIINACIPLIKTNQY
                     KGILCSTYRTFPLTAAKTLAIHTNLPFVVDLRDIIEQYASNEYISHKFHTFSWLDAFI
                     TKRFRKRLLRKRNNALEVADCVTTVSPWHVEVLKQYNPNVKLIYNGFDPELFYPQQIK
                     TSRFIITYTGRLLSLAIRNPELLFAAIARLTEDKVIIPETFRVVWYTDQESRSIIRQE
                     AEQHGVQSFMDYHEYVPASDIPLILNKSSVLLSLTNKFDTSGPKGFMTTKFFESLAVE
                     KPILCVQSDEAYLAEAIKETHSGLAATRVDEVYDFLKHYYEEWQEKGYTTSPINRDKL
                     SNYSRKEQASQFARIFEEI"
     gene            complement(14179..14814)
                     /locus_tag="ACZPB4_02810"
     CDS             complement(14179..14814)
                     /locus_tag="ACZPB4_02810"
                     /EC_number="3.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019213 - deacetylase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L deacetylase family protein"
                     /protein_id="HIR1097189.1"
                     /translation="MITNCKNILVLAPHTDDGELGLGGTISRLIEDGKKVTYVAFSTA
                     QQSVPEGFPKDILKTEVKQATQTLGIEPGNLIIYNYEVRKLGYARQEILEELIRLKKV
                     SDFDLVFIPSLHDIHQDHTTIAQEGLRAFKNTNILGYELIWNNLTFNTQCFVRLEERH
                     IDAKVESLKAYKSQGARDYLSKDFIYSLARARGVQAGCTYAEAFEVIRLFL"
     gene            complement(14853..16160)
                     /locus_tag="ACZPB4_02815"
     CDS             complement(14853..16160)
                     /locus_tag="ACZPB4_02815"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010184336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HIR1097190.1"
                     /translation="MGMKNRTLHYIIRFLVGDDVPSELVETIGYTADPNKFDRYNVVI
                     IPSGFFDGQTYGTPASLPELPLQEVQGIPLLFGSPKEEWIRDTWVVHADIIASTYFLI
                     SRYEEMIRRGLRDEHGRFPGKESLPYRAGFLHRPIVDEYRMLLHCWLRQSRLRVPEVK
                     KQIRKIYLTHDVDSPTLYRSWKGLIRSIRDRRGLYKSFQGKFGTLEKDPFYTFPWFFR
                     QNSILQDLIGKEQCHPILFIRNGGKAKHDKPHYDLRNKDIRKLIKSALEHNVTIGLHS
                     SYQAGTTPSLIRKEKTGLEDHIGKNVRFNRHHFLAIREPEDMDQIEAAGVTDDFTMGY
                     ADVSGFRLGTCYPVRWINPITRRLSPLRLHPLIIMDCTLEEEKYMGLDFDRALTYCRN
                     LVEQVNNVGGELVLLWHNDSVQEGSGSYLRKLYAQLLKELAKQ"
     gene            complement(16151..17104)
                     /locus_tag="ACZPB4_02820"
     CDS             complement(16151..17104)
                     /locus_tag="ACZPB4_02820"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIR1097191.1"
                     /translation="MSNKDKYRLLCNTEKNIPIFSHDWWLDTVCGEKKWDVLLIEQKG
                     KIQATLPLYVPHSDIVSMPSYTQTMGPWFTASSSDTKYTTELGRRQELCKQFTEELKR
                     YPHFLQNFNYDITDWLPFYWAGYNQTTRYTYLLKNIRDHQAVWENMSPNIRRNITKAQ
                     NKYHISVKKGIPLNEFLAVQAQTFDRQHVRIKEDTNVLKDLIATCRQRGQGDLWGGYD
                     EQGHLHAAAFIVWQDRSAYYLAGGGNPVYRGSGAQSYVLWECLHFVSQFTTVFDFEGS
                     MLPGVERFFREFGAIQTPFFTISRGKLSLLDRARIKLSKWV"
     gene            complement(17146..18198)
                     /gene="recA"
                     /locus_tag="ACZPB4_02825"
     CDS             complement(17146..18198)
                     /gene="recA"
                     /locus_tag="ACZPB4_02825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HIR1097192.1"
                     /translation="MAKEENLFEEKAKEEGGKPAANTDKLKALRAAMDKIEKNYGKGS
                     IMKLGDENIEDIEVIPTGSIALNAALGVGGYPKGRIVEIYGPESSGKTTIAIHAIAEA
                     QKKGGIAAFIDAEHAFDRFYAEKLGVDVENLWISQPDNGEQALEIAEQLIRSSAVDII
                     VIDSVAALTPKAEIEGDMGDSKMGLQARLMSQALRKLTAAINKTNTTCIFINQLRDKI
                     GVMFGNPETTTGGNALKFYASVRLDIRSIGKLKDGDEIKGNQVRVKVIKNKVAPPFRK
                     AEFDIMFGQGISRSGEIIDLGSELNIIKKSGSWYSYNDTKLGQGRDAAKQCVEDNPEL
                     ADELSELIFEALKANK"
     gene            complement(18208..18666)
                     /gene="bcp"
                     /locus_tag="ACZPB4_02830"
     CDS             complement(18208..18666)
                     /gene="bcp"
                     /locus_tag="ACZPB4_02830"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008158590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016209 - antioxidant activity [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-dependent thiol peroxidase"
                     /protein_id="HIR1097193.1"
                     /translation="MAVQIGDKVPEFLGTDQDGKEVKMSDYKGKKVALYFYPKDNTSG
                     CTAEACSLRDGYQALQAKGFEIIGVSKDSAKSHQGFIQKQNLPFRLIADTDTTLQEQF
                     GVWAEKKMYGRSYMGTLRTTFIINEEGIVTNIIGPKEVKTKDHANQILNL"
     gene            complement(18668..19861)
                     /locus_tag="ACZPB4_02835"
     CDS             complement(18668..19861)
                     /locus_tag="ACZPB4_02835"
                     /EC_number="1.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014225714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016646 - oxidoreductase activity, acting
                     on the CH-NH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA];
                     GO_process: GO:0009085 - lysine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HIR1097194.1"
                     /translation="MGRVLVIGAGGVSTVAVKKIAMNADVFTDIMVASRTKSKCDKIA
                     ADIKNVKVQTAQVDADNVQELVALFNAFKPDLVVNLALPYQDLHIMDACLEYGVSYLD
                     TANYEPLDEAKYQYSWQWAYKDRFEKAGLTAILGCGFDPGVTGVYTAYAAKHHFDEIH
                     YLDIVDCNAGDHHKAFATNFNPEINIREITQRGKYFEDGEWKETDPLSVHKALNYPNV
                     GPKESYLMYHEELESLTKNFPTLKRARFWMTFGQEYLTHLRVIQNIGMARIDPILYNG
                     QEIVPIQFLKAVLPNPGDLGENYTGETSIGCRIRGIKDGKELTYYVYNNCSHHAAYLE
                     TGAQGVSYTTGVPAMIGAKLFMQGIWKKPGVWNVEEFNPDPFMKELNEQGLPWHELFN
                     IDLEL"
     gene            20064..22349
                     /locus_tag="ACZPB4_02840"
     CDS             20064..22349
                     /locus_tag="ACZPB4_02840"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1097195.1"
                     /translation="MRFLNYAGGVFILLLLALGCKPEAKRSRVLVIQSFRWDDKNYLE
                     LNSDIRKELRKNRVNADIRTFYLDCECYMAEEEEERMYNFIDTIRLWKPDIILVNDDQ
                     ATYTLMKCGHPFVKKVPVVFSGVNFPNWDLLEKYPNVTGSWDKIDYKENLRLIDQQMG
                     KSRIYINYDKTSLGQLAFRELIKAVDTSRYVLNYNQLAFQLNDPDFKVDSMTFRTEMR
                     MKAIRPSKNVIHFMPFRKANGEFLLSNINGTYPYCVFFNIRYDYTSAGLSKMFVTPSF
                     TAVREIFNINVEVLGGYFCSNRIQAAEQARLAAKILSGTPVSSVPIVESPKEYLYDWG
                     EMQRLGISKEEVPTNVHIINMPISERYKIGVFIASSLGVILLLALIGYLFYLYWREAR
                     RRKAVLANLKQEKEHLSLALEGGNIFAWKLQSGTFRFDNEFFSYVNISPREIPLDELY
                     EMTHPDDRQSLRSLIDFICTGTISHHILQYRCDFNGKGYQWWEFRYGSLEDANDGYVI
                     NGLCLNIQNIKDTEEVLISAREKAEESDRMKSAFLANMSHEIRTPLNAIVGFSNLMNS
                     EEVLEPEEREQFVKLINTNSDLLLKLINDILDLSRMESGKMSFVFDRHDLNVLINEIY
                     CTFQLMMPEGVELRMRVPEIPVVVAVDPYRLKQVLSNFINNAIKFTTSGYIEVGYYFC
                     TKGDCLHIYVEDTGIGIPEEKQKQVFDRFCKLDEFAQGTGLGLAICQVIAQRFGGEIQ
                     LKSEYGKGSRFMLTLPKERIG"
     gene            22356..23543
                     /locus_tag="ACZPB4_02845"
     CDS             22356..23543
                     /locus_tag="ACZPB4_02845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="THUMP-like domain-containing protein"
                     /protein_id="HIR1097196.1"
                     /translation="MEQIEELSRFIKEHASDDLNRLLLSASRYPGIDIPFVVDQLKSR
                     RQIKDKLPSWYQNDRLVFPAKIAAEQCSSEQTALYKQRLVDPQAHVCDLTGGLGIDSY
                     FFSRKVRQVTYIERFPAYCEAAIHNFKVLDVGNVTVLNGDSTELIDKIDGIDVFYIDP
                     ARRGEGNKRVFALQDCEPDLTKLVPVLFGHAPKVIAKLSPMADIHMTLDLLPDVTAIQ
                     VLSVKNECKELLFVLERGSKGGSPQICCVNFTSEEEPELFVFSLVEEREAVASIRGEV
                     KRYLYEPNASILKAGAFKAVATRFGLNKLHVNSHLYTSDEVVPSFPGRSFVVDEVIPF
                     TNKQCKTLSRQIPQANITVRNFPLSVDELRKRTKIADGGTIYLFATTLENGDKVLIKT
                     HKI"
     gene            complement(23726..24556)
                     /locus_tag="ACZPB4_02850"
     CDS             complement(23726..24556)
                     /locus_tag="ACZPB4_02850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008771845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097197.1"
                     /translation="MKKSFVSLLTIAAITFGMVSCNSSKKQDAAEQKVEEEAAIAGEV
                     SKGLLTAELKDEVTRFLKDMPDSELPYKVSTGEVTISVANTDFMLPVSKVSELNTQAQ
                     KARACGIYFADLNVLKAMKKPTTDIENVLVKLTTDLDIPFAIDIMKESAPANASKEEL
                     SKFMKDQENKLIDAMMENDKADVELELLGGMAVEYAIVYANPGLVVKGDAISAGLSEN
                     MEKRIGIIQQITADLAKYYPDLEQLGTTIAPLSGMVATINTARESKAKIEEMRANLLK
                     "
     gene            complement(24591..27512)
                     /locus_tag="ACZPB4_02855"
     CDS             complement(24591..27512)
                     /locus_tag="ACZPB4_02855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HIR1097198.1"
                     /translation="MNETILNGLLNLFAIFASLAKIESDQARQAVNSYLTSHFGIRSH
                     KEYMELFEEIQSVYDDPEFDIDRESVIINVCNQLKPKLIAEDQLLLLLRFMEFAHGNN
                     EGLNENLAIFHKIATIFNIDTDTFDNLYAFVVGKKSPSILTINADDSDKDVNHIYRRG
                     LEGEIRVLRLTRFDRMVFIYQGSGRVFMNDIPLTSGIFYGWQRSSVIKSPLFLPVYYS
                     DVLDVFNQNEHKERILLTGRDIEFSFKNSENGMHNFSFNLESGQLVAIMGGSGVGKST
                     LLSILNGNIIPGEGSVCLNGHPLSDPECKQLIGFVPQDDLLIEELTVFQNLWYTARLC
                     FANLTEKEIEDRVNTILEDLDLSKIRDLAVGSPIRKTISGGQRKRLNIALELIREPAI
                     LYLDEPTSGLSSTDSEKVIMLLKEQTHRGRLVVVNIHQPSSEIYKLFDRLWLLDTGGY
                     PIYDGNPIEAITYFKRIANYTDQDISVCGTCGNINPELILTIIDAKKIDDSGNQTNIR
                     KITSKEWHELYVASRPKFQEVKPTPLPPNHQQKPSIWKQFCIFLERNIKTKLTNKQYL
                     CIALLETPLLAVIVALLTRFVPDDGYSLLANKNLVSYIFMAVIVATFTGLSISAEEII
                     KDRTLLKRERFLRLSRGSYLSSKMFYLLCISAIQSLLFIVVGNLLIGIGSEMFLTWWI
                     TLWATSFLANLTGLVLSQSLNSIVAIYITIPLLLIPQILLCGLVVKFDDLSRSASSRN
                     IVPLIGEVIPSRWAFEALVTEQFRNNSYNRLFFTVEKEKFLAQYYRNVHADEVRSLIN
                     SLNLIPEKREKNTRTIHNELAVLSRAARIAPYTSKESYESYMDKVEKALHTRSDNFTA
                     LLEKKRKEVIQEHGSEWLNTLKKEHHNSAIEELVLNSTSTQFYKEAHNRIYPKIGQIY
                     LEPDNNWGRAPFYSHEKKFAGYTFSTFTFNLLMLGIFALLVIISIFAEFPGKYLNKGS
                     D"
     gene            complement(27596..29263)
                     /locus_tag="ACZPB4_02860"
     CDS             complement(27596..29263)
                     /locus_tag="ACZPB4_02860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative transporter"
                     /protein_id="HIR1097199.1"
                     /translation="MNWLLETLTEPSMIQAVAVISIVAAVGVYLGRLKIFGISLGITF
                     VFFAGIMAGHLGITVNKDMLNFAQNFGLIVFVYTLGLQVGPGFFSSLKKGGVEMNTMG
                     LGVIALGLILTLVFHWITGISVPVMVGLLSGAVTNTPALGAAQQALLQMDPENTRNVT
                     DMALACAVAYPLGVVGVILAIIILRSLFAKKTQSTHKEQDTTTNVAEFQVLNPSIYNK
                     SIQQVMKLTEKHFVISRLWRNGKVTIPTSETILKEKDHLLIISVKADVESIKVLFGEQ
                     ETTDWNKEDIDWNAIDSQLISRRIVVTRNRVNGVKLGSLRLRNLYGINITRVNRAGID
                     LVASRDLRLQIGDKLTIVGEANSVNNVGKILGDELKRLDNPNLLAIFVGLTLGVLIGA
                     IPIAIPGMSTPIKLGIAGGPIIVGILMGAFGPRFHLTTYTTQSANLMMRQFGIVIYLA
                     GLGIDSGAHFFETVFRAEGLLWIGLGFLLTIVPVLIVGFIASQFFKLDYAHNIGMLCG
                     SMANPMALSYANTTVEGDEPSVSYATVYPLSMFIRVISAQLLIMLFT"
     gene            29361..29714
                     /locus_tag="ACZPB4_02865"
     CDS             29361..29714
                     /locus_tag="ACZPB4_02865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097200.1"
                     /translation="MRETMVKYIKWLLPVLFIAYYSSVSLFTHVHVEHGTTIVHAHPF
                     KKTADGTCHHHTSLAEIQLFHMLSSIHVMDGAIHLLRLQFYSLKISNLSESPVYPDHV
                     TSVEGLRYLRAPPVV"
     gene            29814..32120
                     /locus_tag="ACZPB4_02870"
     CDS             29814..32120
                     /locus_tag="ACZPB4_02870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HIR1097201.1"
                     /translation="MNKFITLILCLCCVFTSAWAEGDDHTSLNPSDANIVGHILDKKT
                     GEHLSFINVYLHGTTIGTTTDATGHYYMKNLPEGKYTLVMKSIGYKTEEKTVTLKKGK
                     TLEINFNAEEDAVSLDGVVVSANRNETTRRLAPSLVNVLDSKVFETTHATSLAAGLNF
                     QPGVRVENNCQNCGFQQVRINGLEGPYTQILVDSRPIFSALTGVYGLEQIPANMIERV
                     EVMRGGGSALFGSSAIAGTINIITKEPMRNSAQIAHSLTMIGGSRPDNNTTVNASLVT
                     DDHKAGIYLFGQGRHRASYDHDGDGYSELGKLEAKTLGFRSYLKTSNYSKLTFEYHNI
                     SEFRRGGNLLDLPPHETDITEQTDHQINGGGLKFDLFSRDYHHRLNVYTSAQHTKRQS
                     YYGAGKDPNAYGNTTDMTFIGGAQYSYEWDKCLFMPATFTGGAEYSYDDLQDEMLGYH
                     RTIAQTVHIGSAFAQNEWKNDRWSFLIGGRLDKHNMMDHVIFSPRANVRFNPTKDINL
                     RMSYSSGFRAPQAFDEDLHITAVGGDVAIIQISPDLKEENSQSVSASVDFYHRFGPVQ
                     VNFLVEGFYTDLRNVFILEEIGRDEDNNLLMERRNGKGARVMGINLEGKMAYSWMQIQ
                     AGATLQRSRYKEAEQWSENPNITPQKKMFRSPDVYGYFTSTFTPVKRFSASLTGTYTG
                     SMLVQHLAGYIPEDREEKTRDFFDLNLKLSYDFPIFKSATLQVNAGIQNIFDSYQDDF
                     DKGAHRDAGYIYGPGIPRSYFVGCKISY"
     gene            complement(32312..34192)
                     /locus_tag="ACZPB4_02875"
     CDS             complement(32312..34192)
                     /locus_tag="ACZPB4_02875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0031419 - cobalamin binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="B12-binding domain-containing radical SAM
                     protein"
                     /protein_id="HIR1097202.1"
                     /translation="MGLASVLLVLSPFTQINTPYPSTAYLKGYLEAKGVHAGQTDLGI
                     ETILALFSTQGLGELFAEIERRKGKYPAKVRGMLANKQRYIDTIAAVVAFLQGKNDPL
                     AYRICNQDYLPESDRGSQNEEELEWAFGTSGLRDKARYLATLYLEDLCDLIRETIDPD
                     FGFSRYAEHLGRCASSFDEIEEALQKPFGFIDRLTQPLLEKHIAESKPKAIAFSVPFP
                     GNLFSTLRLAQWLRQAHPDIPILMGGGFVNTELRSITDTRFFKYIDYLLLDDGEDPLF
                     QVLRYLDGAIPKEELVRTFSLDESGSRVVYQDNPAYPACRQNETGFPDYEGLPLDKYI
                     SVMEMANPMHKLWSDGRWNKLTLAHGCYWGKCAFCDGSLDYIKRYEPNTAKTLVDRME
                     RLIEQTGEIGFHFVDEAAPPALLREMAQEIIRRGITVVWWGNIRFEKSYTEELCDLLQ
                     RSGCIAVSGGLEVASPRLLKLINKGVTVAQVARVANNFTGAGIMVHAYLMYGFPTQTA
                     QETIDSLETVRQMFELGLIQSGFWHRFAMTAHSPVGLHPAEYSCRVTEPPFGGFARND
                     VQFEALSGCDPELFSEGLRVSLYNYMNGTGFDLPLHKWFGGMKVPRTTLPPNYIERIV
                     EE"
     gene            complement(34210..34812)
                     /gene="yihA"
                     /locus_tag="ACZPB4_02880"
     CDS             complement(34210..34812)
                     /gene="yihA"
                     /locus_tag="ACZPB4_02880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="HIR1097203.1"
                     /translation="MEIKSAEFVISNTDVRKCPEGNKPEYAFIGRSNVGKSSLINMLT
                     NKKGLAMTSQTPGKTLLINHFLINNEWYLVDLPGYGFAQRGKENREQLKRIIENYILD
                     REQLTNLFVLLDCRHEAQKIDLEFMEWLGESGVPFSIIFTKIDKISKGRLKENLKVYT
                     DKLLETWEELPPIFLSSSEKKEGRDEILDYIESINNSLNN"
     gene            complement(34857..36320)
                     /locus_tag="ACZPB4_02885"
     CDS             complement(34857..36320)
                     /locus_tag="ACZPB4_02885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HIR1097204.1"
                     /translation="MNSYMILFIIAAYFAVLLLIAWITGRNNSNEAFFLGNRKSPWYI
                     VSIGMVGTSLSGVTFVSVPGMVRAIDMTYMQTVLGFFVGYIIIAKVLLPLYYKLQLTS
                     IYSYLDDRIGRRGYKTGASFFLLSKIVGAAARLYLVVLILQTYVFNAWNIPFAVTAIL
                     SILLVWLYTFRSGIKTIIWTDTLQALCLVAMLIVIIWQVKDKMGLDFGGMAQTLVESP
                     HFRIFEFGDWHSTQNFFKQFFSGIFITIVMTGLDQDMMQKNLSCKSLKDAQKNMYTYG
                     FAFTPVNFLFLALGVLLLTLAAQQNIQLPTLNDDILPMFCTSGILGGSILIFFTIGII
                     AAAFSSADSALTALTTSFCVDILGVQREEAKRAKRTRLKVHVMISVLFVLIILAFKAV
                     NNRSVIDAIYMIASYTYGPLLGLFVFGLFTKRKPRDKYVPYICIASPLICLATDFLVK
                     QYAGYTFGYEMLMVNGGITFAGLWLSAIENGNLKIEN"
     gene            complement(36362..37945)
                     /locus_tag="ACZPB4_02890"
     CDS             complement(36362..37945)
                     /locus_tag="ACZPB4_02890"
                     /EC_number="3.1.-.-"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA];
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0009166 - nucleotide catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HIR1097205.1"
                     /translation="MGLKKQFVSAILLGSALTAPLFAQDIATPSSSIDTLAIFSFNDF
                     HGAFASDGITPGAARLVQMTQNEKQRYPHSIVVSGGDNFSGSYFSKITKGEPIKEMYE
                     AMDVEMSAIGNHEFDWGLSYLVDTAALNIPHVAANITEEKRYTHPNWLSPYRIVERKL
                     KDGSSLRIAFIGLTTTDTYVKTKPENLKGLQFTHPLGAVCIQTVYQLKKEDQIDMIIL
                     LMHIGTDMKMPYRITEENAQGLPFIDKVDAIISAHSHELVLDKINNIPIIQAGVNGTH
                     IGKLLFQIQDFNGHRDISFIQGDTVRVACEENPEMREAVEKIMDKYRLNEKLATAKEA
                     LIHDRTINKFDYTPIGALVTAAYAQRFQKEMPAYKDQPVIGVNHYGGIRAALPKGDIT
                     RLRAGNILPFGSAIVAYRFDGKRLKKLLEDGRKNPNGFLQSSDLTLTLSGNKIEKIVY
                     TRDGQKTEIEDNTSCVVTLDAFITDGGDGYDASLFKGYEIPEFDNLGIISTDAFMDYL
                     KGFKKPITVESTHMPVISK"
     gene            complement(38171..40549)
                     /locus_tag="ACZPB4_02895"
     CDS             complement(38171..40549)
                     /locus_tag="ACZPB4_02895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1097206.1"
                     /translation="MKNIGIAIRSLFKRGQHNVMKIISLGIGLTIGLVLIAKVHFENT
                     YDNFYPNGDRIYRVYEKFFMNGEVGDHGQTPAGVIPLLKQETPEIEAATRYTYFRGNS
                     PFTMSDNKHRLKATFILADSCLFDVLPRPMLIGDPKQVLSQPMYVLVSDEIAERIGGN
                     VMGKRFEIDDAPGQALTIGGVFKKLPDNTEQSYDIIVSLSSISKFMWDGTHMLTGNDR
                     YQSFVKVSPGTTEAQLEAGMRQMIDKHFPVNDLKKAGVELTFTFHKLLNVHMEDDMAK
                     RMALILSFIAFVLIFTAVMNYILIVISSIVNRTKEMAVRKCYGASGKDIQGMALSEVG
                     THVTVALALVVLLILGFQGIIKELIGTGVRSLFLSTGMWAICLTVIVVLISTGIATGW
                     FLGRIPVAAVFRSIREARRLWKLGLLFFQFTAISFLASLLLVVGKQYDHMVNDHPGYN
                     PENLAYVYIGAVDSTGRAKLIEETQRLPEVDAITTCYNLPFWGASGNNVYLPGDDREL
                     FNIADLYDVGNDYLNVLEIPIVEGQYFTENTTSSQEILVSRNFIEYMKPFADWKDGAV
                     GKTVQITGHDTKSESMPLFTIRGVFEDFRLGSIAGEDPRAKIMFYTKGAAQHMVIRYH
                     SLSSEALRKTQDLMGQLIPDKELNVISFKSEMLEGYTSSRKFRDSVMIGGIVTLLIVF
                     IGLIGYTNDEVNRRRKEMAIRKINGATVKDILHIFLKDIITIALPAILLGCGIAFYIS
                     QKWQEQFSEKIQLSWYLFVGGGVLVLTVILAVSGYNVFRTTHDNPVNNLKSE"
     gene            complement(40698..42011)
                     /locus_tag="ACZPB4_02900"
     CDS             complement(40698..42011)
                     /locus_tag="ACZPB4_02900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030435 - sporulation resulting in
                     formation of a cellular spore [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIID/LytB domain-containing protein"
                     /protein_id="HIR1097207.1"
                     /translation="MEAPVINVGIMTHKAISFVFNEEYVHTETGTFTIGEQRALWVNG
                     KIVYNGKLYQELFFEPTSPQSSFDLKAVTIGVDFHWQRQEDQRFKGALNLVATDKGIV
                     TINQVDVEEYLTSVISSEMSANASKELLKAHAVISRSWLLAQVEKNFNLNGSVTPYKS
                     CYRDSETLIRWYDREDHDLFDVCADDHCQRYQGITRASNPIVREVIKETRGEVLMDND
                     TICDARFSKCCGGVTEKFENCWEPVPHSYLTALRDDEIPSYPDLTDEREAEQWIRTSP
                     EAFCNTTDKEILSQVLNNYDQETTDFYRWKVEYTQEELSRLIHRKTGMDFGPIIDLIP
                     LERGSSGRITKLKIVGVRRSFTIGKELEIRRTLSETHLYSSAFVVDKKDIRLDIPSRF
                     ILTGAGWGHGVGLCQIGAAVMGAKGYSYRKILTHYFPGASIEKRY"
     gene            complement(42029..44026)
                     /locus_tag="ACZPB4_02905"
     CDS             complement(42029..44026)
                     /locus_tag="ACZPB4_02905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0035673 - oligopeptide transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006857 - oligopeptide transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OPT family oligopeptide transporter"
                     /protein_id="HIR1097208.1"
                     /translation="MKPENEEKVTGLPENAYRELKEGESYKPLMSPNKHYPEVTPWSV
                     LWGLVMAVIFSAAAAYLGLKVGQVFEAAIPIAIIAVGLSSGFKRKNALGENVIIQSIG
                     ASSGVIVAGAIFTLPALYILQDKYPEITVNFFEVFMSSLLGGIIGILLLIPFRKYFVS
                     DMHGKYPFPEATATTQVLVSGEKGGSQAKPLIFAGLIGGLYDFIIATFGWWGETISTR
                     IVGAGEMLAEKAKIVLKVNTGAAVLGLGYIIGLKYSLIICAGSFLVWLVIIPAMSAIF
                     SADVLTFGNDAITATVGSMSAEQIFTTYARHIGIGGIATAGVIGIINSWGIIKGAVGL
                     AANELKGKGDAVESNTIRTQKDLSMKVITIGIIVSLIVTFLFFQFGVLHNWFHAAIGL
                     LLVGVIAFLFTTVAANAIAIVGTNPVSGMTLMTLILASIILVAVGLKGPAGMVSALII
                     GGVVCTALSMAGGFITDLKIGYWLGSTPAKQETWKFLGTLVSAATVGGVILILNQTYG
                     FTTGQLAAPQANAMAAVIEPLMSGSGAPWALYAIGAVLAVVLNFCKIPALAFALGMFI
                     PLDLNTPLLIGGAISWYVGSRSKDQSLNSARLEKGTLLASGFIAGGALMGVVSAALRF
                     GGINLMNEEWASSNAAEILAVVMYLVMIAYLTFNSLNAKKE"
     gene            44511..45137
                     /gene="recR"
                     /locus_tag="ACZPB4_02910"
     CDS             44511..45137
                     /gene="recR"
                     /locus_tag="ACZPB4_02910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination mediator RecR"
                     /protein_id="HIR1097209.1"
                     /translation="MNQRYPSALLENAVNELASLPGVGRKTALRLALYMLRRDVGYTE
                     NFAAALVALRRDVKYCKVCHNICDDEVCSICANPSRDHSLVCVVENIKEVMAIENTGQ
                     FRGVYHVLGGIISPMDGIGPGDLRIDSLVRRVAEGEVKEIILALSTTMEGDTTNFFIY
                     RKLSGYDVRISVIARGVSIGDEIEYADEITLGRSIINRTEFNLTSSNS"
     gene            45163..46329
                     /locus_tag="ACZPB4_02915"
     CDS             45163..46329
                     /locus_tag="ACZPB4_02915"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009101 - glycoprotein biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HIR1097210.1"
                     /translation="MTYEETKLSVIIVNYNVKYFLEQCLYSVRAAVTGMDAEVFVVDN
                     NSTDGSVEYLRPKFPEVVFIENKDNPGFAKANNQAIRQCTGEYVLLLNPDTVVGEESL
                     RSLCFQMDEDPEIGAIGVKMLNGHGVFLPESKRAFPSPWVSFCKIFGLSKLFPNSPAF
                     ARYSLPYLDKEQTHKVEVLAGAFMLLRHEALDKVGLLDESFFMYGEDIDLSYRIVLGG
                     YKNLYVPERILHYKGESTKHGDLRYIRAFYGAMLIFYKKYYPGAGWLMRILIRLAVLL
                     KACWAMISAPLRKKAKAVKHRRLLILCREDHFEEVKAVCLKAMPDLEFVNLWDLDVER
                     VMDAICRKNQMKGFTDYAFCFPDARYEQMLLFMDKLVNKKAVFHIYTKKSGRLV"
     gene            46347..46862
                     /locus_tag="ACZPB4_02920"
     CDS             46347..46862
                     /locus_tag="ACZPB4_02920"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIR1097211.1"
                     /translation="MLLSNDRVRLRALEPEDLELLYRWENDPELWEVGNTLAPYSRYI
                     LKEYIAGSDRSIYESRQLRFMIEECDTGTSVGIVDLFDFEPHPNRAACGIMLDRRYQG
                     RGFATEALRLLMEYAYTFLKLHQLYVHIPVANEPSKKLFTRLGFVEAGTLKDWIRTPD
                     GYSDVCIMQLI"
     gene            complement(46854..47450)
                     /locus_tag="ACZPB4_02925"
     CDS             complement(46854..47450)
                     /locus_tag="ACZPB4_02925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgE/AlgH family protein"
                     /protein_id="HIR1097212.1"
                     /translation="MASYKNIFKITHNDVLPAQGSILISEPFLQDAYFQRSVVLLIEH
                     TEHGSMGFVLNKKTDLIVNSFFKEFAEFPEIPIYLGGPVSPNRLFFIHSLGDNIIPDA
                     LKINDYLYFDGDFNALKRYILNGHPINGKVKFFLGYSGWTEGQLNHEIKRNSWAVSHI
                     TTDNILSADGEGYWKDSVELLGNDYKTWTKYPKDPYLN"
     gene            complement(47571..48884)
                     /locus_tag="ACZPB4_02930"
     CDS             complement(47571..48884)
                     /locus_tag="ACZPB4_02930"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HIR1097213.1"
                     /translation="MKNTPVDYQTARRIIDGFGLPDFGKATIREVVAISTQLEQETGT
                     EFIHMEMGVPGLKAAQVGVDAEIEALRNGIASIYPNINGTPEVKKQASRFIKAFINID
                     IDPECCVPVTGSMQGTYASFLTAGQCTPGKDTILFIDPGFPVQKQQIAVMGYKYESFD
                     VYEYRGERLREALEAHLSKGNIAAMIYSNPNNPAWFCLTDEELKIIGEMANKYDVIVI
                     EDLAYFAMDFRKDLGCPFEPPYQASVARYTDNYIMQISGSKAFSYAGQRIGVTAISNK
                     LYHRSYPGLTQRYGGGTFGTVYIHRVLYALSSGTSHSAQFALAAMFKAAADGTFDFVS
                     QVKEYGRRAEKLKKIFTDHGFTIVYDHDLDQPIADGFYFTIGYPGMTGGQLMEELVYY
                     GVSAISLSTTGSNQQGLRACTSFIKDHQYDLLDERLRLFEENHQA"
     gene            49028..49101
                     /locus_tag="ACZPB4_02935"
     tRNA            49028..49101
                     /locus_tag="ACZPB4_02935"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:49062..49064,aa:Asp,seq:gtc)
     gene            49247..50149
                     /locus_tag="ACZPB4_02940"
     CDS             49247..50149
                     /locus_tag="ACZPB4_02940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIR1097214.1"
                     /translation="MENLIKIDTVDQYNKMFGLETLHPLVSVVDLSKSETWPTNFRVN
                     YGIYGLFLKDTKCGDIRYGRQYYDYQEGTVVGFAPGQVTGIELKDGTRPLAHGLLFHP
                     DLIRGTALGRDIKRYSFFSYESNEALHLSEEEKGIFVDCLRKIQIELEHSIDKHSKRL
                     IAMNIELLLDYCLRFYDRQFTTRAETNKDVLVRFERLLDEYLQSDLLRQEGLPTVRYF
                     AEKICLSPNYFGDLIKKETGKTAQENIQDRIISLAKEWILGTNKTVSQIAYDLGFQYS
                     QHFSRIFKKTVGCTPNEYRKSQMS"
     gene            complement(50163..50726)
                     /locus_tag="ACZPB4_02945"
     CDS             complement(50163..50726)
                     /locus_tag="ACZPB4_02945"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008771860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016407 - acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HIR1097215.1"
                     /translation="MTLNEFLKYVETRKPLKGDEIHQFMNKMSDEARRMTFELNGSYH
                     DPEEIRELLSRLFNKPVDPSFRVFPPFYTDFGKNITVGKNVFINACCHFQDHGGVTLD
                     DGCQIGHNVVFATLNHGFAPEDRSTTYPAPIVLKKNVWVGSNATILSGVTIGENAIVG
                     AGSVVTKDVPDNAIVGGVPAKVIKYIQ"
     gene            complement(50852..52096)
                     /locus_tag="ACZPB4_02950"
     CDS             complement(50852..52096)
                     /locus_tag="ACZPB4_02950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="family 20 glycosylhydrolase"
                     /protein_id="HIR1097216.1"
                     /translation="MSDQPIDFTQRNIAIDILRAVTICVMIFESVHQIKNLNIKTYRY
                     MKKIIGLFLLIWAIGSAQVSAQSETNRLDSIMPVRGLAIAAPSAQKLDLFLKFVQEEL
                     APSHFNLLILRVDWNYAYESHPELRDPTPLTREDVKKIVKVCRDNGIRIAPQINLLGH
                     QSWAETTYALLREYPEFDETPHVDTKNYTGWPNSDGLYCKSYCPLHPEVHKIVFALVD
                     ELTDVFETQLFHAGMDEVFYIGHDSCVRCGGHDKAELYAGEVTKIQNHLASQGKRLMI
                     WGDRLIDGKTTGIGAWEASMNNTHRAIDLIPKDVFICDWHYERAEQTAVYFAMKGFDV
                     ATCPWRKPQIALQQVDDMIHFRQHSNPEMSRHFQGIIETVWSGADSFLEAYYNPTTYK
                     QEVSDAVTVKKLIEKYKALENQ"
     gene            52197..52694
                     /locus_tag="ACZPB4_02955"
     CDS             52197..52694
                     /locus_tag="ACZPB4_02955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097217.1"
                     /translation="MIDMIRRLIYWVLLLFVCMGAHAQFRVTAHQEGWDRIPPQAQKD
                     GFWFQQSVLANMDDDAAMEEVMLFGRDNGHYPTFDLFKFYYVIVDNYTREIQYISDEI
                     YVTDKYALTVEDRNNDGISELYIDYFKDGKFTVDERGYNLRTTRCYDRIEWSPESEKF
                     NPQQP"
     gene            52691..53602
                     /locus_tag="ACZPB4_02960"
     CDS             52691..53602
                     /locus_tag="ACZPB4_02960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ThuA domain-containing protein"
                     /protein_id="HIR1097218.1"
                     /translation="MRKYIYFIALICCALSASTSYAQKKVIKTMMIAGQDGSHYWRGA
                     CEAMKQILENSGMFKVDFVFTPDFGGDINTFKPDFAKYNLVVVNYGGEVWPEPVQKAF
                     ENYVADGGGVVIIHSSVVPMAGWKAYNEIIGMGAWEGRNEKDGPYLYWKEGKYVYDYT
                     PGYAGYHGLQHETILEHRAPEHPILKGLPIRWKHFKDEIYTRLRGPVRNVEILATAYE
                     RGRHEPLMWTVKWGKGRVFVDLLGHCGNDPNMIYSMECTGFQVTLLRGAEWAATGEVT
                     QEAPRDFPLEDTCTLRPEFKAPFHATN"
     gene            54136..56379
                     /locus_tag="ACZPB4_02965"
     CDS             54136..56379
                     /locus_tag="ACZPB4_02965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HIR1097219.1"
                     /translation="MSNQEYIKIEGAYENNLKHISLDIPKKQITIFTGVSGSGKSSLV
                     LDTIAASSRRELNETFPSFVQQYLPKYGRPHVDRIGNLPVAIVIDQRKPAPNARSTVG
                     TYTDIYSLLRLLFSRVGKPFVGYSDTFSFNHPQGRCTRCDGLGEIRELDVHKLVDFDK
                     CLNDEDVIHYVTFQPGQWRWIRYACSGLFDLDKKIRDYTPEELRLFLYSPQIRLKNPP
                     ADWPKTAKYEGLVTRMYRSIINSEEGKIHQKVLEPMVTMGICPDCGGTRLNDKVLSCR
                     INGRNIAEVTHMAIPEIIAWLREIDDPLAKDMKQAIGGRLSALLEIGLGYLTLDRSME
                     TLSGGEAQRCKIAKYINSSLSDMLYVLDEPSVGLHSHDIHLLKASVRKLRDHGNTVLL
                     VEHHKEMIQIADHIVDMGPGSGMEGGRILYEGDYAGLLRSDTLTGRMLGENTPLKESL
                     RIPSGWFTVKHARLHNLKDVTVDLPMGVLAVIAGVAGSGKSSLMECFRRDFPEEVIYI
                     SQKNIGISLRSTPATYLGVADDIRKLFAKESKAGLSMFTFNGKGGCPVCGGKGVIVSD
                     MAFMDSIETVCEACGGLRYSPEALRYTVDGLTIAEVMDLTVRKASLRFAGTVIAEKLR
                     PLMLVGLGYLHLNQALSTLSGGELQRVKLASYLGTQSKVFVLDEPTDGLHVKDVRHII
                     SLFDSMVDQGNSVFLIEHNLDVLKAADYVIEIGPGGGLMGGEILFSGTPKELLSCERS
                     VTKDYLV"
     gene            complement(56455..59277)
                     /locus_tag="ACZPB4_02970"
     CDS             complement(56455..59277)
                     /locus_tag="ACZPB4_02970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding domain-containing protein"
                     /protein_id="HIR1097220.1"
                     /translation="MKRFWSIPLMLMLFACQTPKESREELSLAGCWELRLDSTDVTEQ
                     VQLPGTTDTNQKGYPNNDKEETTHLSRPFRYQGKAWYQKEITIPENWEGKSIWLILER
                     TKPTQIWVDSIYVGSSDHISTPQEYDLSAYLRAGKHHLTILVDNGLSVPPQLLDNSHA
                     YTESTQTNWNGIIGDLKLEARPQFHIRRIQVYPHADQKTVDVKIKLSNPFEQMIVAAV
                     QIEMEAFNTGLEHHIKFNKNIVVQQDEIIFQIPMGDDALEWSEFSPTLYRLTANIQGE
                     NIQDSQSTTFGLRDFKAEGTQFNINGLTTFLRGKHDACVFPLTGHVPMDTAAWRRYFR
                     IAKEYGINHCRFHSWCPPKACFEAADIEGFYLQPELPFWGKMEKGDTTLIHFLTKEGL
                     QIQEAYGNHASFVMMAIGNELSGDQEAMVDMIARFRSEDGRHLYASGSNDYLGFNGPA
                     AGDDYFTTCRVPGANVFSNHTRGSFSFADAEDGGYINHTYPNSVMNFESAIEQCSLPI
                     IGHETGQFQCYPNYEEIKKYTGALKPWNLEIFRKRLGESGMAGQADDFFKASGKWMAQ
                     LYRAEMEMAFRTPGMAGFQLLDLQDYPGQGTALVGILDAFMDNKGLITAKEWKESCDD
                     VVLLALLPKFCYSGNEALKGSIKVANYTPTTLKGKHLTWTLTNSQDQVIAQNNIPLQI
                     NQGTLAEVGPLNIALPAIQEAETYTLRLAIEGTDYHNHYPLWIYPEHNNVQIPTDINV
                     IKKWDKQAENLLANGAKVLWFPDAKTYKNVTVEGLFQTDYWNYRMFKSICEWVKKPVS
                     PGTLGLLMNPSHPVFAHFPTDFHTNWQWFTMIKNSHPLILDQLPDNYRPIVQVIDNVE
                     RNHKLGMIQEFNVGPGKLLICMTDLETQQEYPEVRQLYHSLLSYMDSSEFSPQMTLTP
                     AQLIELFTHQVGDSKIKELGNISYDE"
BASE COUNT        15278 a        13158 c        14111 g        16870 t
ORIGIN      
        1 aacttttaaa tctttatggc tattacgacc ttttatcggg aatttgcgtt ttgtgggaaa
       61 gttgggcaaa aaagtaagtt aacttcatcg gcaaagtaac ttaacatact ttgccaacga
      121 acctaagata cttggttgat gaagctaaga tatgtctttt cttaaatcac ttgtcaaatt
      181 tgcctcagct tcttacgctc ggaatagccc gaacctacgt atcccccaaa tacggaaaag
      241 gaaaagaagt gtctcagaca cgactaccat cattgctacc gtgatagggg cgatcattcc
      301 gcaaacatat aggatcgcta atccagtgat gtgtaccatg gaggtggtca taactgtata
      361 gttcgtatat agagggtgcc ccatggccgc cagaaatgga tatcctagta acatagaggg
      421 gatggttacg aaacaagcga ttacaagtat ccggaatact tctaagatat ccggatcggc
      481 tgtcccatag acaaatctta atacataact tgagaataaa agtacggtcg ttacgcaaaa
      541 gaagttggag aatgttattc tatagaatac ttttttaaag aacaagacat ctctactttt
      601 cgctatatgc ggaaataaaa ccccagtgaa tggtgtcaat aactgattgt acgcttgata
      661 tagcttctct gctgccgaat agtaacccac cgctgtgttt ccgcaaatca aacccaatag
      721 aaacgagttg cttgtggtga acaaagaggt agaggcccgg gagagaaaat aagtggaact
      781 atcttttaag gagttactaa cttcttcgat tgatgtgaag taccatttca tccccattct
      841 gaagtaaaca ataaagatac taacgatccc ggcaagaata aagccaaaac tatagcatat
      901 cggtacgtat atataatttt ccggttttcg aatgaagatg aaaaagggaa ggaaactcaa
      961 tgatttcgct acgatattga ataccgtaat gtatttcata ttctccatgc cttgaaaaaa
     1021 ccacatagga aacataacat tgcctatgat catgccaaaa tataggagat aaaaagaaga
     1081 ttctgactta aacttatcaa aacaagtgat cagaatgagt agtatggcga agctgacccc
     1141 acataaaaag aaacgtccaa gcattgtgct atttaggtaa gagttgattt tacctaaatc
     1201 cgttttatgc tcagagatat atttcgtggc tgataggtta aagccaaaat ccgtaaacat
     1261 aatgaaatat tgcatcaagg catagccgaa cgtcacgagc ccccagcgtt ctacaccgag
     1321 tactctgaaa agaaaaggaa atgataataa aggtaataaa taattaactc cttggagcaa
     1381 tgccaaggag ataaaattta taaccatagg attcttgagc ttctttttta tttccatata
     1441 ataaagaccg gattgaactt ccttatttat tcaatgaagt cagcgcttct attagcttat
     1501 cattgtcttc cttgttccgg atagcgattc ggatatattg tttcccttca aaccctgctt
     1561 tagttccaca gttttttatc aagatattat ttcccgacaa taaagagcta caaagttcct
     1621 ccgatgtgta agtatcggtt acttcacata agaaataatt tgcggcggaa ggaataaccc
     1681 taagatatga gactgcctgt agattctgga agaaacgctc tctttcgttt aagaatttat
     1741 ggcaggcttt gtcgtagtca tcactgtatt tcacgaaaat ctgcatataa aattcagcga
     1801 aggagttgat gttccaaatc gatatgtctt ttttcaacgt tcttatgaga tctttgtttc
     1861 ccgacgctaa gaaacctaat cgtaatccgg gaacgccgta tgactttgat atgctcttaa
     1921 tgacaatcaa atgtggatat ttgtttaaaa gctctttatc taacagggaa agtttatttt
     1981 caggatttgc gaaatcaagg aaagattcat ctatgattaa acgaatccct tttcgttcgg
     2041 accattcgac tagcgcaaat atctcatttt tagataataa atttccagat gggttatcag
     2101 ggttaattat caaaagttgc tcaatcgctt tgttatcaaa gaaagatata atgtctaaag
     2161 cagtataaga gaagtctcgg ttgctgggag tataatacac cagctgctta ggggccaaac
     2221 ggttcgggta ttcctcgaat gttggtaata taactcctgt ggtatactta gaggtcatac
     2281 gcatataacc actgattaac tcggccgctc cgtttcctac gatgatttgt tcggaggata
     2341 ttcccgcata acgggcggct agttgagcgt tttcttgcat accggaagga tattcggtaa
     2401 ggagagtatc gaaattggct ttcatttctt ccttcaatcg ggtatttggg aaataagggt
     2461 tgacgagata gcagaaatcc aataacatag ggaaacgcca gtatccaccg taacgtttgc
     2521 cgtataaaga taatgcttgc ttgccttccg aaaataaggc ttccgcatta tttaagtcct
     2581 gttggtcatc tatctcatac catttttcgg ttgtaatcgt caaggccttt aaatccggtc
     2641 tgtctaataa ggatattacc tttagaactt gttcgtagta ttcattatta ccgagggctt
     2701 tacaataagc ctccaagaac ggaatatact tattagtgga aaattcctta ctgaatttat
     2761 atatatttac ggtcttgtaa taagactcct tttggcaaaa ttgaaacgct ttctttgaga
     2821 tgaagttcaa tatattgtta tcctcatcca gccgtacgac ggtaccatcc atccaacttt
     2881 ggtatttggc aactactgcc aaatttggat agggatggtt tatcaatttg ctgagaatgg
     2941 agttctcaaa aattagatcg gattcaagta gaattgtctc gtcctccacc agatagtttt
     3001 tagcgagata tagcgagtat atattatttg ttttatcata tacattgttc tctacataaa
     3061 gaacaggagt gttgtttatc ttatctccga taagctcacg taccttttct cctttataac
     3121 ctatcacgat aattatacgt ttcagagata gagcttccag ttgtttaagc atacgttcga
     3181 ttaaggtttg attatgtacc ttaatcatgc attttgtgtt gttttttgtc aactctttaa
     3241 ggcgtttgcc catgcctgcc gctaatatga tcgcttgcat atcttattct tttttaattg
     3301 tataaacaaa tacccctgtc gattttactg tcaaaatatc aatttgactg tacataaccg
     3361 agaaggggtt gtctttataa gatgattcta ttatctaaaa cgctgcatat aatgtaaacc
     3421 gatatcatat ccagaatttt gatacctctc tttctatctt aatctctgga gattgcgcag
     3481 ataaactatc ataaatttta cttgcgaata gaatatcatg tagaccaaga cctatattgt
     3541 aacttaatat ccgttcatgg tcattttctc tgccagccgt tctacctgat aaaacgtctt
     3601 ctagctcggc atattgtttg aattgggaaa aataacggaa tcccttcaca tgatcggtat
     3661 catcgccata taccttgtcg aaaaagagat cgcaattttg aaatcctctc gtatgtatcg
     3721 gcacgactag gcatccttct ttaaataggt catttttcgg acagatcaag ttgcttgcgt
     3781 ctgttataca actgataata acatctgagt tggatatgag attctctata ttgtctatga
     3841 tcgagaatgt aacattggga taagccccga atctctctat aaaggaatcc gcttgatcct
     3901 tatattttaa tagctgaact gtatgatgcg tatttttttg gctatcaagt aaacataaca
     3961 tagttgctct agctgtattt cctaagccga tgaaactgta agtagtggca tcggtcgctt
     4021 ttaatgtttg gatagcgaga gtggcgacag ctcctgtacg catagcggtt atccaatctc
     4081 cacccaatag ggctaatagt tctcccgtat tggaatcata gagtaggata tcgcttccta
     4141 aagcaggtat gccacctaca atacgatgaa ccaccttgat tccaaaccta gagaattctt
     4201 ggggtaagag gcagggcatg gaagtgaaaa agtcattacc ttgggggtgt acacttattt
     4261 ttgcgggtaa ttgagccttg ttttttatag agaaactttc tttcgcccaa tctacacagg
     4321 tcgcaggcgt aattcctaaa tccttaatct gattttcaga gataattttc atattgactt
     4381 ccttttttag ttcatgctta tgccaaaaaa gcttccaaag ttatgtataa ttcttgaaat
     4441 agtcttactt ttgtatctct tttaaatgca ctataaacat aagtaataga tatatatgaa
     4501 aatagcgatt gtaggtacag gctatgtcgg gttggtaacg ggtacttgtt ttgcggaaat
     4561 ggggactgag gtcttttgtg tggacgtgga taaggtaaag attgagaatc taaagaaagg
     4621 catagttcct atctatgaac cggggctaga cgagatggtg gcacgcaatt cccaagctgg
     4681 tcgtcttcat tttatgactg atttaaaaga atgtttgaat gaggtcgagg tactgttttg
     4741 tgcggttggt acacctcccg atgaggatgg tagcgcagac ttgaagtatg tgcttgaggt
     4801 tgcccgtacg gtaggacgct atatgaataa atatatcttg gttgttacga aaagtacggt
     4861 tccggtaggc actgcccaga aaatcaagaa agcgatcaag gaggaacaag ccttgcgaga
     4921 tgtgagtatt gaatttgata tcgcttctaa tcctgaattc ttgaaagaag gtgcggctat
     4981 caaggatttt atgagtccag accgggttgt tgttggggtt gagtctgatc gtgctcagaa
     5041 gttgatggcg aaattgtatc gtcctttttt gttaaataat ttccgtgtaa tcttcatgga
     5101 tgtgccatct gcggagatga caaaatatgc ggcgaacgct atgttggcta ctcgcatcag
     5161 ttttatgaat gatattgcca atttgtgtga gatagttggg gcggatgtta atatggtacg
     5221 taaaggaatc ggtacggatg cccgtatagg tagtcgtttc ttatatgcgg gttgtggata
     5281 cggtgggtct tgttttccta aagacgttaa ggcgcttgtg aagaccgcag ccaacagtgg
     5341 ttaccaaatg cgtatcctag aagcggtgga agccgtaaac gaggagcaga aatcgatatt
     5401 gttccgtaaa ttaatgaaac attttagagg agatatacaa ggtaagcgaa ttgctttatg
     5461 gggattggca tttaagccgg aaacggatga tatgcgagag gctccttcgc tagtcttaat
     5521 caaaaagttg aaagaagccg gatgtgtaat ttccgcctat gatccggttg caatgcccga
     5581 ggctcaaaga cgtttacctg tgggggtgat ttcatatggt aaagatattt atgagaccgt
     5641 gatagatgca gacgctctgt tgcttgttac ggaatggaaa gaatttcgta tgccctcctg
     5701 gtctgttatc aagaaattga tgtccacgcc tttaatttta gacggacgta atatttatga
     5761 caagacagag ttagaggaaa ccggctttat ctatcattgt ataggtcggt aaattttaat
     5821 tatacgagat tgtatgaatc tccggatagt tacaatcatt agaaggttta taggcaccga
     5881 aataggtgat gtaaatcttc ttttcttttg tatctacagc atagatacaa aaactgttac
     5941 ttgataggct atcctcttca cgtatgaccc tgttgtatac cacgcctttt tcacttggag
     6001 cttgattggt acaaaggatc attttttgtg gaacgagttc cgtgctttcg ttttctaatc
     6061 cagtcacgtc aaaataggcg ttgcagtgga tatgtccacc tagatagcag acaaattctc
     6121 ctttgcggtc actgaaatct gctttgacat tgatggggtc taggttgaat tgatttggat
     6181 atactttttc taataaggaa cgagtacgaa aggcttcaat gatttcggga atcatattcc
     6241 acgaatggac ataatcccca tcacataaat aggtatcgtt atttacacta cggcgttgaa
     6301 atgggtaatg agttaagata atgacgctat gatggtctgt catgccattt tttaatgcgg
     6361 tgtttataag ccagtctatt tgtttctggg agaaatatgc gtaagataaa gtattatatt
     6421 gggatgctgg ttggtctaac atatcgaggg cgatgaaacg gatcgtacct ccttgagggt
     6481 ttgctacatc cgaatagtaa taattctcgg cactatttcg attcttcgaa taattactgt
     6541 tggcgaataa tatttcgttg atctcgtttt tataaaagaa ggtactgcct atctcttctt
     6601 cggaattact atcatgattt cctgtacaaa taaaggtggg gacatgattt tcatcataaa
     6661 ggtaatgaat aaatgagtgc atatattctt tcgccttctt tttcttatca atagagataa
     6721 aatcacccgt agcggttatc gcattgatcc gcagttcttg ttgattggcg aattggatgg
     6781 attgtcgtag atttataggt aactcgtaat tattgctcgg agaccaagag gataaatgag
     6841 aatccgaaat atggacgatc ttaaaacgtt cataacttcc actatctgtt ttattgtaca
     6901 tgattttcgc tagtctctga gctgcgagct tattgttttc ccaataaaaa ggttcattct
     6961 ctccgctacg caagttaagg tttttccaat catctttaca gcctactgat aagatcagca
     7021 ggataaaaag ggcatatatt tgtaaggccg tgttattcat aacctatggt gtattagaat
     7081 aacgcaaata taaaaaatat tttgttattc cttcattcta aactcttttt tcaacgaaca
     7141 cccactacac ccacagcaag gatcactgga tttcggtttc gtaagcattc gataaacctt
     7201 atatgcgata tatccgataa ccgagatacc aataacgcaa actgctatat cttgccacat
     7261 acctataaat ttacctccta tatataacta aataaaacat aggaaagttc ttagctgaat
     7321 aaacccacaa agaaattccc cgtttgataa acaatgaaag aaacgatcca tgctaggaca
     7381 caagtataaa tgataacgaa tataccccat ttccatgagc cagactcgtt gacaatagcc
     7441 gatatagtcg ctatgcacgg aaaataaatc aagacgaaaa gcattaagct aatcgctatg
     7501 agcggtgtga ataccaaatt accttccgcg ttacggtctt gcttcaaacg ctccgacagg
     7561 gcttggctgt catcatcggc attccccgtg tataatacgc ttaacgtgct gacaacaact
     7621 tctttcgccg ccataccggt aagtaggctt acactcattt tccaatcgaa tcctaaagga
     7681 gccaagatcg gttgaatcgt ctggccgata cgcccgatat acgaattttg ttggtggtcg
     7741 attgccttca agcgttctaa ctcctctatc gtatctgttt tttcttgaga atccaactcc
     7801 gtattttcga tctccgctat ctggcgatca aactgatctc cgctctccga atgtctgggg
     7861 aaatacccaa ggaaccagat gatgatagaa gcgaccaaga tgatacctcc catcttgtgc
     7921 aagtattgtt tcgctttctc ccacatatgg atcatgatgg atttgccggt aggcatccgg
     7981 taggggggga gttccattac gaaaggaaca tcctcctcgt taaacaggaa gcgtttgaaa
     8041 agacgggcca tgataactgc cagcaagatt ccggatacat ataaagctaa taacacaaag
     8101 ctggcgttct tcgggaaaaa cgccccggtc agcaatacat aaaccggcag gcgggcgcta
     8161 cagctcatca acggatttac caacatcgtt atcatccggc tattacggct ctctatcgta
     8221 cgggaggcca tgatagcagg aacattacaa ccgaatccca tcactaaagg gatgaacgac
     8281 tttccatgca gtcccatctt atgcatgatc ttatccatga taaaagccgc acgtgccata
     8341 tatccggagt cttccatgaa cgatatgaac atatacagaa tcaagatatt cggcaggaac
     8401 acgataacac ctcccacgcc accgatgata ccatccacga gaagatcctt caaaggtcct
     8461 tccgacatat ggttgcgcac gaaattaccg atcacctcga ccaatgcctc tatccattcc
     8521 atcggatagc ctcccaaacg gaaagtggcc tcgaacatga tccacatgaa taggataaag
     8581 atagggaagc ctaagacttt atgcgtgacg aatagatcga tgatctgcgt actcgttgcc
     8641 tctttgatca tattttgttc gtaagtctca cgcaacgctc cggaaataaa gccatagcgt
     8701 gcgttcgtga atgcggtctc acaatcctct tgcaataact tttctattag ggctgtatta
     8761 cggtctcttt cttggaagat cgtttcggca ccgggcagcg tttttataaa tgtctctatc
     8821 tcccggtctc cctctaatag cttgatagat agatagcgct ttgacaagct tttgggtata
     8881 tccacgctat ttttcaaggt cttcctaacg ttgctgatcc ctttctctaa agactctccg
     8941 taattaatat ggatatgacg gatgacagga tcttcttctt cgtatacctt gattacacgg
     9001 ttaaacaaat cctctatgcc aaagcctgtt ttacttacgg tcgggataat cggtgccccg
     9061 atcattttcg ctaaggactc atgatcgaat ttattaccat ggcgttccag ctcatcatac
     9121 atgtttaagg cgattaccat gcgaacgtcc atatcgatca gttgggcggt caaatatagg
     9181 tttcgctcca gattggatgc gtcgataaca ttgatcacca cgtctggttg ctcttcattc
     9241 aaatgcttac gcacgtataa ttcttccggc gtgtaagcgg atagggagta agtacccggt
     9301 aaatctacga tgcggaatgt atagccattc tgttggaagg ttccttcctt ggcatctacg
     9361 gtcacgccgc tatagttacc cacatgctca tgtgctccgg atgcgaaatt gaaaagagag
     9421 gtctttccgc agttcggatt accaaccaag gctacgttaa ttgtttttcc tttatgtaat
     9481 gcgatggctt gcaattcatt gccggaaggc aggataaaag agtctgcact cctgttcgta
     9541 tcttgtaccg aggtagcttg ttccttctcg aaatccgccg cgctaacgac ttcgatcaat
     9601 gcggcgtccg agcgtcgcaa tgagacatca tatcccatta cacgatagtg aatagggtct
     9661 ttgagcggag cgttttgtat aacgatcact tctttccctc tgataaatcc catctcgata
     9721 atgcgtttgc ggaaagctcc gcgacccatt acctttacta taacaccttt atcgcctgtg
     9781 cgaagttctg ataatctcat gtcctattaa atgttacgcg aaggtagctt gaaaacttcg
     9841 taccaccaat accaactaat aggtattttt ttatttccat gggttgtttt tcgagtattt
     9901 tatgtatgtt tgtgccacaa atttcaactt tagacaaatg aaactacgaa ttactttgtt
     9961 caccacctta ttggttcttc tgtctgcttg ttttacaggc tgtaaaaaag aattgaagga
    10021 tttctctttt agttatagta tggaaagtgt agataactac aaactaatgg ttctgtttga
    10081 tagtgacaag acattccgta tcgaggagta taattattat atggataatt tcgccaagaa
    10141 acgagatcct aaaattatgg aggggacatt gactgacgag gagtttgctt ctttaaaacc
    10201 gattctgcaa aaatgtaatt tctttaagat gaaagactct tatggctttg aggaggagac
    10261 gaaccgggat ttaggggata tcatgtatca ggtttcattt accacggaag gtaaggagaa
    10321 atttatctct atccgtaata gcgataccgg acaattttcc gcttctttcg tgaagttgat
    10381 cggttttatc aatacattct tgaataatca taagaatgac taaacgcttt tagccggaga
    10441 tggagaataa acgaaaccgg gttctattgt gcttaggctc taattgggat aaagagaaaa
    10501 atatggagcg cgcggcggag atgctgcgtg ctcattttgt ttttatacag ttttctcagc
    10561 cagtttatac ggaaccgatc gattgtccat tatcaactac atttttgaat cgagtggctg
    10621 ttttgtatag cgaggagagt ccggcgcgaa taaaggatgt cttgaaagat atagaatgct
    10681 gcatcggccg taagccggaa gataaatctt gtgggcgtgt gccgatagat attgatttat
    10741 tgcagtggaa cgaccaaatc ttgaaagcag aggacttgac ccgtgaatat gttctagatg
    10801 gcatctgctc gctccttgcc gcaggagaga atgatgaatg gtgccaatag aaaaccaaag
    10861 gagccgctgt tgcggatcaa tgcgttgata cctttgcata tcaaagaaag aactgggttg
    10921 tttcggtctg cgttataaaa tcctttctct actttaagct tgaactggta gggtgccaat
    10981 aagtcctcat aagtctgtat gggaaggatt cgttcggccc aattacctgt agccggatcg
    11041 caagtattgt atgggtcttc cgggcttggt aaactctttt tctcgatcgc tttttggata
    11101 tcgggatagg tcaagcctct agtctgccgg gcccatgtct ctacttcttt tggggagaaa
    11161 gccgggcaaa gtttcgttat gaattgctct cgtaatgtat aatagttggg ggattccaaa
    11221 gatccacttt cgcatccgat catcatctta tgtaaccgtt gttggacata cgggttgaat
    11281 ggtgtagagg ctgtcgtgaa tagtagatac atggaatcgt ttatatggat taaatccttg
    11341 aagaacaaag ataaatcata gacatgttct atcaggtccg tagcgattaa aagttggggg
    11401 gagactttgt tccttgcgca ccagtccgca agaacatctg aatctccatg gagtatggta
    11461 tcggggccta ttcctattat ttgtttcaat agctggatcg tctccacgga agatgggtta
    11521 agatcaatat aaataacttg tcctattcct atggatttcg ccagaatact aaggaagccg
    11581 gttcctcctc cataatcgat tagcgtgaca tcggagatag gggtttgtat cgcttgaagt
    11641 cctctttgta ggcaatctgc gtatatatgc atgaaatagc ttaacgccgg ctttaagttg
    11701 ccgatgtatc gcttattata atcgctgata ggtaatttat tatagtcgat cgctttcaaa
    11761 cgttcggtta atgtatgtaa taaatcactt ctattctctt tcatcatata tcatcttgta
    11821 taaacgtatc ccctgatctt cattagaaaa agcagggaac aataattgtt ttcgtttatc
    11881 tatcgcctct ttatctatag gtagggccat taattgttcg caagcccgta tcatctcatc
    11941 cggcgtatcg gcgatatggc ataaaggatc taatccgcta cccgctagca tgagatgatt
    12001 gacaatcgta tgccttccgg cgaataagct gttcaaaagc tttagtttta ggccggtatc
    12061 ttgaaatgtg attagcatat gaatttgtgc gttgtggatc aatgcgtcca tacgttcctt
    12121 actgggattt gcttctactt ttatatgtgg gtaaggagcg gctgcctctc gtatcaaacg
    12181 ggtcgggttc atgcccgcta ttatgcaggt atgttttaat tggctgaaaa catgcttggt
    12241 gagaaataac acggctcgct cattctcgat aacggataac ttgccatgat ataaaatata
    12301 atcggatttt cccggtttgg ccgtaatccg gttattctcg tggaaacaag gaacgaactc
    12361 gatcctttga ttgggaaatt gttttcgtaa atagtctgcg tctgtcgtgg atacggcgat
    12421 tatcagattt gcgtactgtg ctactttctg ataggcttgg aagcgcatgg cctcgatctt
    12481 gaaaaaggca ttgcgaacca atcctttgcc agactttgcc aagtggcgat aataatcgtg
    12541 ctcgatattg cactcccgga atatcttcat ccggtttctt aaacggggat cgtccatata
    12601 atagcaggag tggaggccct caaataagat cgggtaatca ttttgtaaaa gattctcgat
    12661 caagcgatga tctttacggc tatatacatt gtaagggagc catgttaaat tagcgattac
    12721 cccggtacgg cgtttataat agaaaacctt gtcgcaaatg ctttctaatt ccggtgcgtg
    12781 cggacgttca tattcgaaac aatgtaatat gagtttcacg ccgcatgcat gcaaggcctc
    12841 cagtttataa tacacatcaa tgacccctcc gtaattggcg ggataaggta tattgaacga
    12901 tactatgttg aggtatttat ccatctgctt aaatctcctc aaatatacgc gcaaattggc
    12961 tagcttgctc tttccgggaa taattcgata gcttatcccg attgatgggc gaggtcgtat
    13021 atcctttttc ctgccattcc tcatagtaat gtttcaagaa atcgtacacc tcgtctaccc
    13081 gggttgcggc cagtccagaa tgggtctcct tgatggcttc ggcgaggtaa gcctcgtcac
    13141 tctgtacgca taagatgggt ttttctaccg caagcgattc aaagaactta gttgtcatga
    13201 agccttttgg accagacgtg tcaaacttat tcgtcaagga aagcagcacc gagcttttgt
    13261 tcaagatgag gggaatatcg gatgccggta catactcatg gtaatccatg aaagattgca
    13321 ccccatgttg ttcggcctct tggcggatga tggagcggga ctcttgatcg gtataccata
    13381 caactcgaaa agtttcgggg ataatgacct tgtcctccgt aagacgggcg atggccgcaa
    13441 ataataactc cggatttcgg atcgctaaac ttaacaaccg tccggtatag gtaatgataa
    13501 accgggaggt cttgatttgt tgcggataga acaactcggg atcgaatccg ttataaatca
    13561 gttttacatt gggattatat tgtttaagta cctccacgtg ccaaggcgat acggtcgtga
    13621 cacaatccgc tacctccaaa gcgttattcc gctttctaag taaccgtttg cgaaatcgct
    13681 ttgtgatgaa tgcgtctagc catgaaaatg tatggaattt atgcgatata tattcgttgg
    13741 aggcgtattg ctcgataata tctcgtaaat ccacgacgaa agggaggttg gtatggatcg
    13801 ctaacgtctt ggcggcggtt aaaggaaagg tacggtatgt gctacacaat attcctttgt
    13861 actggttggt ctttattaag ggaatacatg cgttgattat tttcatgtct ttataaccaa
    13921 acaagatgtc tagaaacatg acccacatcc attcgatatg ctttgagatc tttcctgatg
    13981 ctttgtagta gcggacgcaa tacacgtccg cataccccgt aaggaattcg aatgtattgt
    14041 cttctatgta ttctgtcact acggtaactt cccatcccat gcgtgtcaaa tatttgcata
    14101 gatatcccat tctgggggcg aaagcgggtg ggaacatatc acatatgata aggagtttat
    14161 tcatggattc aatcagggtt ataagaatag acgaatgact tcaaacgctt ccgcataggt
    14221 acatcctgct tggacgcccc gtgctcttgc taatgaatag ataaagtcct tggatagata
    14281 atctctcgct ccttgcgatt tataggcttt caatgattct acctttgcgt cgatatggcg
    14341 ctcttccagc cttacaaaac attgtgtatt gaatgtcagg ttgttccaga ttaactcata
    14401 acctaatata ttcgtgtttt tgaacgctcg tagaccctct tgggcgatcg tcgtatgatc
    14461 ttggtggatg tcgtgcaagc tagggatgaa gactaggtca aaatcggata cttttttcag
    14521 gcgtattaac tcctctaata tctcttgtct tgcgtatccc agttttctta cttcgtaatt
    14581 gtatatgatt aggtttcccg gttctatacc taaggtctgg gtcgcttgct tgacctctgt
    14641 cttcaagata tctttcggaa aaccttcggg aaccgattgc tgtgcggtgg agaaagccac
    14701 ataggtcact tttttaccat cttctatcag gcgtgagata gttcccccca acccaagttc
    14761 cccatcatcc gtatgagggg cgaggactaa aatattttta caattagtaa tcattctttc
    14821 tgatttattt gaatacaggg attttgttgt tttcactgct tcgctaattc ttttaatagc
    14881 tgggcgtata atttacgtaa ataacttccg gacccttctt gtacggagtc attatgccat
    14941 agtaaaacca attcacctcc tacattattt acttgttcca ctaaattccg gcaataggtt
    15001 aaagccctgt caaaatccag tcccatatat ttttcctcct ctagggtaca atccattata
    15061 ataagcggat gtagtcggag aggagatagc cggcgggtga tcggattgat ccaacgaacc
    15121 gggtagcaag tccctaaccg gaatccggag acatcggcat accccatggt gaaatcgtcc
    15181 gtaaccccag cagcctctat ttggtccata tcttccggtt cccggatagc caagaaatga
    15241 tgacggttga accgaacatt tttaccgata tgatcttcca gaccggtttt ctctttccgg
    15301 ataaggctgg gagtcgtacc cgcttggtag ctactatgca aaccaatagt tacattatgc
    15361 tctagagcac tttttatcaa tttacgaata tctttattcc tcaaatcgta atgaggtttg
    15421 tcgtgcttgg ctttcccccc gttccggata aataggatag ggtgacattg ttccttcccg
    15481 atcaagtcct gaaggatact attctggcgg aaaaaccaag gaaaggtata aaacgggtct
    15541 ttctcaaggg taccgaattt accttgaaag gatttatata aacctcttct atctctaata
    15601 gaccgtatca aacctttcca cgaacgatat agagtcggag aatctacgtc gtgcgtgagg
    15661 tagatcttcc ggatttgctt ttttacctcg ggtacacgta accgggattg gcgtagccaa
    15721 caatgaagca gcatgcgata ttcatccacg atcggacgat gcaggaaacc ggcccggtag
    15781 ggtaaggact ctttaccggg aaatcttcca tgctcatccc gaagtccacg ccgtatcatc
    15841 tcctcgtatc tggaaattag aaaataagta cttgcgatga tatcggcatg aaccacccat
    15901 gtatctctta tccattcctc tttcggcgag ccgaataaca aggggatacc ttgaacctct
    15961 tgcaagggga gttccggtaa ggaagcggga gtcccgtatg tttgtccatc aaagaagccg
    16021 gatggaatga taacgacgtt atatcggtcg aatttattgg gatcagccgt gtacccgatc
    16081 gtttctacca gttcgctagg gacatcatct cctacaagaa aacgtattat ataatgtaaa
    16141 gtgcgatttt tcatacccat ttgcttagtt taatgcgtgc tctgtctaat aaactcaatt
    16201 tccccctaga tattgtgaaa aatggggttt ggatagctcc gaactcgcgg aagaaacgtt
    16261 ctactccggg tagcatagac ccttcgaaat caaataccgt cgtaaattga gaaacgaaat
    16321 gaagacattc ccacaggacg tagctttgcg ctccggaacc tctatagacc ggatttcctc
    16381 ctccagcgag atagtaagcc gatcgatctt gccatacgat gaaagcggcc gcatgtaaat
    16441 ggccttgctc gtcataacct ccccataaat caccttgtcc tctttgtcgg caagtggcga
    16501 tcaagtcttt cagtacattc gtgtcttcct tgattcgtac atgctggcgg tcaaatgttt
    16561 gggcttgtac agctaggaac tcattcaaag gaatcccttt ttttacggat atatggtatt
    16621 tattctgcgc tttcgtaata tttcgccgga tattggggct catattctcc cataccgctt
    16681 gatgatcccg gatatttttt aataaatagg tataacgtgt cgtttggtta tatcccgccc
    16741 aataaaacgg aagccaatcc gtgatgtcat aattgaaatt ttgcaggaag tgcggatagc
    16801 gttttagttc ttccgtgaat tgtttgcata gttcttgacg tcgtcctaac tcggtcgtat
    16861 atttcgtgtc ggaggaactt gcggtgaacc aagggcccat tgtttgggtg taagaaggca
    16921 ttgagacaat atcggaatgg gggacgtaaa gggggagggt tgcctgtatc tttccctttt
    16981 gttctataag caagacatcc catttttttt ctccgcaaac cgtatccaac caccagtcat
    17041 gtgagaagat cggtatattt ttttcagtat tgcaaagtaa acgatatttg tctttattac
    17101 tcattacaat ttcgtatagg ggcggggggt gcccgcccct gcaaattact tgttggcttt
    17161 taatgcctca aatattaatt cggataattc gtctgccaat tcgggattgt cctcgacaca
    17221 ttgttttgcc gcatcacgac cttgtcccaa tttggtatca ttgtagctgt accacgaacc
    17281 gctcttcttg atgatattca gttcagagcc aagatcgatg atctctccgg aacgggagat
    17341 accttgaccg aacatgatat cgaactctgc cttgcggaat ggaggagcca ccttgttttt
    17401 tatgactttc acacgcactt ggttaccctt gatctcgtca ccatctttca gctttccaat
    17461 actacggata tccaaacgga ctgaggcgta gaacttcaac gcattaccac cagtcgtcgt
    17521 ttccgggttc ccgaacatta cgccgatctt atcacgcaat tggttgatga agatacaggt
    17581 cgtattcgtc ttattgatcg cagctgtcaa tttacgaagg gcttgcgaca ttaagcgagc
    17641 ttgcagaccc atcttgctgt ctcccatatc gccctcaatc tcagctttag gagtcaaagc
    17701 ggctacggag tcgataacaa tgatatctac ggcggatgaa cggatcaact gctcggctat
    17761 ttccaaggcc tgctcaccgt tatccggctg ggagatccat aggttctcta catcaacgcc
    17821 taacttttca gcatagaaac ggtcaaaagc atgctccgca tcgataaatg cggcgatacc
    17881 tccttttttc tgagcctcgg cgatcgcatg gatcgctatg gttgtcttac cggaagattc
    17941 cggaccatag atctcgacga tacgtccttt cggatatccg cctacgccca gcgctgcgtt
    18001 taaagcgata gagcctgtcg gtatcacctc gatatcctcg atgttttcat cgcctagttt
    18061 catgatcgaa ccttttccgt agttcttctc gattttatcc attgccgcac gtaaagcctt
    18121 tagcttatcc gtgttagcgg ctggtttacc accttcttct ttcgcttttt cttcgaacaa
    18181 attttcttct tttgccatat gtgtccctta taaattaagg atttgatttg catggtcttt
    18241 tgtcttcacc tctttcggcc cgatgatatt agtaacaata ccttcctcgt taatgataaa
    18301 ggtggtccgg agagtcccca tgtatgaacg tccgtacatt tttttctcag cccacacacc
    18361 aaactgttct tgtaaggtcg tgtctgtgtc cgctattaaa cggaaaggta agttttgctt
    18421 ttgtataaag ccttgatgcg atttggcgct atctttgctt actccgatga tctcgaagcc
    18481 tttcgcttgt aaggcttgat agccgtcacg taagctgcat gcttccgccg tgcaaccgct
    18541 cgtgttatct ttcggataga aatagagcgc tacttttttc cctttatagt cactcatctt
    18601 tacctcttta ccgtcttgat cggttcccaa aaactcggga accttatcgc ctatttgtac
    18661 tgccatatta caattctaag tcaatgttaa acaattcatg ccaaggcaaa ccttgctcat
    18721 ttagctcttt catgaatggg tccggattga attcctctac attccatact cccggtttct
    18781 tccaaatgcc ttgcataaat aatttggcgc cgatcatggc gggaacaccg gtggtataac
    18841 taacaccttg cgctcctgtc tctagataag cggcatggtg gctacagttg ttgtatacgt
    18901 aataagttaa ttccttaccg tccttgatac cacggatgcg gcaaccgatg gaagtctcgc
    18961 cagtataatt ctctcccaga tcacccgggt tcggcaatac ggcttttaag aattggatcg
    19021 gaacgatttc ctgcccgttg taaaggatcg ggtcgatacg agccataccg atattttgga
    19081 tgacacgtag atgagtcaag tattcctgtc cgaaagtcat ccagaaacga gcccgtttga
    19141 gggtcgggaa gtttttggtc aaactttcca attcctcgtg atacatcaaa tacgattctt
    19201 tcggtcctac attcggataa ttcaaggctt tatgtacgct taacggatcg gtctccttcc
    19261 attccccatc ctcgaaatat ttgccacgtt gagtaatctc acggatattg atttccggat
    19321 tgaaattggt agcgaatgcc ttatggtgat ctcctgcgtt gcagtctacg atatccagat
    19381 agtgtatctc gtcgaaatga tgctttgccg cataggctgt atatacgccg gtaacccccg
    19441 gatcgaaacc acatcccaag atagcggtaa gaccggcttt ctcgaaacga tctttatagg
    19501 cccattgcca gctgtattga tatttggctt catcaagcgg ttcgtagttg gccgtatcta
    19561 aatagctaac gccgtattcc agacaagcat ccatgatatg caagtcttga taaggtaagg
    19621 ccagatttac caccaaatcc ggtttgaagg cgttaaacaa ggcaacaagc tcttgcacgt
    19681 tatctgcgtc tacctgtgcg gtttgcactt ttacgttctt gatatcggcg gcgatcttgt
    19741 cgcatttact tttcgtacgg ctagctacca tgatatccgt gaagacatcc gcattcatcg
    19801 ctattttctt aacagcaacg gtacttacgc cccctgcacc aataactaat actcttccca
    19861 tttactaata gaattaatct tgttaatata cagtttacaa ggttttcaac caatggacaa
    19921 atatacggct tttccttgac aatccctata aaagatttat ttattcattt tagaagggat
    19981 gaaaggaaag aaagatacag ctaatgaatg tgaatactga aaatagtcgt acttttgtca
    20041 catttactgt ttaaagtttg gacatgagat ttttaaatta tgccgggggt gtttttattc
    20101 tgctcttatt ggcgttgggg tgcaaacccg aggcgaagcg gagccgtgtg cttgtgatcc
    20161 aatcttttcg gtgggatgac aagaactatc tggaattaaa ctcggatatc cggaaagaac
    20221 tgagaaaaaa ccgggtgaat gcggacatcc gcacgtttta tctcgattgt gagtgctata
    20281 tggctgagga ggaagaggaa cggatgtata actttatcga tacgatacgt ctttggaagc
    20341 ccgacatcat attggtgaat gatgatcagg ctacctatac gttgatgaaa tgcggccatc
    20401 cttttgtaaa gaaagttccg gttgttttct ctggcgtcaa tttccctaat tgggatttgc
    20461 tggaaaaata tccgaacgta acaggtagtt gggacaagat tgattataag gaaaaccttc
    20521 gtttgatcga tcagcaaatg ggaaagtctc gcatttatat caattatgat aagacctcct
    20581 tagggcagtt ggctttccgg gagttgataa aagcggtcga tacgagccga tatgtattga
    20641 attataatca attggctttc caattaaatg acccggactt taaggtagat tccatgacgt
    20701 ttagaaccga gatgagaatg aaggcgatac gtccttcgaa aaatgtaatt catttcatgc
    20761 cttttcgtaa agccaatggg gagtttttat tgagtaatat taatggtacc tatccttatt
    20821 gcgtattttt caatatccgt tatgactata catccgcagg tttgtctaag atgttcgtga
    20881 ctccttcatt tacggcggtg cgggaaatct ttaatataaa cgtggaagtt ctgggaggct
    20941 atttttgctc gaatcgcata caagcggcgg aacaggctcg gttggcggct aaaattcttt
    21001 ccggtacgcc tgtctcttcc gttccgatcg tagagagtcc taaagagtat ctgtatgatt
    21061 ggggggagat gcaacgttta ggtatctcaa aggaggaggt ccctactaat gttcacatca
    21121 tcaatatgcc tatttctgaa cggtataaga ttggggtttt tatcgcctct tccttgggcg
    21181 tgatcttatt gctggcattg atcggttatt tgttttatct ctattggcgg gaagcaagac
    21241 gaaggaaagc ggtgctcgct aatttaaagc aagagaagga gcatctttct ttagcgttgg
    21301 aaggggggaa tatattcgct tggaaattac agtctggtac cttccggttt gacaacgagt
    21361 tctttagcta tgtgaatatt tctccccggg aaattccttt ggatgagctg tacgagatga
    21421 ctcatccgga cgataggcag agtttgcgct ccttgattga tttcatttgt acgggtacga
    21481 tctctcatca tatccttcaa tatcgttgcg attttaacgg gaaaggttac caatggtggg
    21541 aatttcgtta cggaagctta gaggatgcga atgatgggta tgtaatcaat ggcttatgtt
    21601 tgaatatcca aaatatcaag gatacggagg aggtcttgat ctctgcgagg gaaaaagccg
    21661 aggagtcgga tcggatgaag tcggctttct tggcgaatat gagccatgag atccgtacgc
    21721 cgctgaatgc gattgtcggt ttctcgaatt taatgaactc ggaagaggtc ttggagccgg
    21781 aagagcgtga gcagttcgtg aagttgatta atacgaactc cgacttacta ttgaaactga
    21841 tcaatgatat tttagatctt tcccgtatgg aatctggaaa gatgagtttt gttttcgatc
    21901 gccatgattt gaatgtcttg atcaatgaaa tctattgtac tttccagttg atgatgcccg
    21961 agggggtaga gctacgcatg cgtgtccccg agatcccggt ggttgtggcg gtagatcctt
    22021 atcggctgaa acaagtattg tctaatttta tcaataatgc catcaagttc acgacttcgg
    22081 gctatataga agtgggatac tatttctgta cgaaaggcga ctgccttcat atctatgtag
    22141 aagacactgg tatcggtatc cctgaggaga aacagaagca agtttttgat cgtttttgca
    22201 aattggatga gtttgcgcaa ggcaccggac tcggactggc gatttgccaa gtgatagcgc
    22261 agcgtttcgg cggtgagata caattgaagt cggaatatgg taaaggtagc cgttttatgc
    22321 taactttgcc taaagaacgt ataggttgac aaagcatgga acaaatagag gaactttcac
    22381 gatttatcaa ggaacatgcg tcggatgatt tgaatcgtct gttgctttcc gcctctcgtt
    22441 atccggggat cgatatccct ttcgtggtgg atcaattaaa atctcggcgg cagatcaagg
    22501 ataaactacc ttcatggtat caaaacgatc gactggtttt tccggcgaag atagcggcgg
    22561 agcaatgttc ctcggaacag actgccttgt acaaacagag gttggtagat ccacaggcac
    22621 atgtatgtga tttgactggt ggattgggga tcgatagcta tttcttctcc cggaaagtac
    22681 ggcaggttac ttatatcgaa cgctttcccg cttattgcga ggcggctatc cataatttca
    22741 aggtgctaga cgttggtaac gtaacggtat tgaatggcga ttctacggag ttgatagata
    22801 agatcgatgg aatagatgtg ttttatatcg atccggctcg taggggagag gggaataagc
    22861 gggtttttgc gctgcaggat tgcgagccgg atttgacaaa gttggttcct gtcttgtttg
    22921 gtcatgcccc taaggtgatc gctaaattat ctccgatggc ggatattcat atgacgttgg
    22981 atttgcttcc ggatgtgaca gccatacagg tgctttcggt gaaaaatgaa tgtaaggagc
    23041 ttttgtttgt gttggagcga ggctcgaaag gcgggagtcc tcaaatctgt tgcgtgaatt
    23101 tcacttcgga ggaagagccg gaattgtttg tgttctcatt ggtggaagaa cgggaagctg
    23161 tcgcttccat ccgtggagaa gtcaagcgtt atttatacga accgaacgct tccatcttga
    23221 aggcgggtgc gtttaaagcg gtcgccactc gctttggatt gaataaattg catgtcaaca
    23281 gtcatttata tacgtcggat gaggttgtcc ctagttttcc gggacgttct tttgtggtag
    23341 acgaagtgat cccctttacg aataaacaat gtaagacctt gtcgaggcag attccccaag
    23401 cgaatatcac agtccgtaat ttccccctct cggtggatga gttacgtaag cgaactaaaa
    23461 ttgcggatgg aggaactatc tatcttttcg ctactactct ggaaaatggg gataaggtac
    23521 ttatcaaaac tcataagata taggatactg cataggtgct gcagcattac tgcataaggg
    23581 ttgcagtact actgctaggc ctgttgcagt actactgtaa ggcttgttgc agtactattg
    23641 caaagcctgt tgcagtgata tccgaaggga tataaaaaag tgtatgatgt tatcaccata
    23701 cactttttat gatatgaggt ttatattact tcaatagatt cgcacgcatt tcctcaatct
    23761 tagcttttga ctcacgagcc gtatttatgg ttgctaccat tccgcttaac ggagcgattg
    23821 tagttcctaa ttgctccaag tctggataat atttagctaa gtcggctgtg atctgctgga
    23881 tgataccgat acgtttttcc atattctcgc tcaaaccggc ggaaatagcg tcgcctttaa
    23941 caaccaagcc cgggtttgcg tatacaatgg catattctac agccatgccc cctaacaact
    24001 caagttcaac gtcagcctta tcattttcca tcatagcgtc gatcaatttg ttttcttggt
    24061 ctttcatgaa tttgcttaac tcctctttgc tggcgttagc gggagcggac tctttcatga
    24121 tgtcgatagc gaatggaatg tccagatccg tagtcaattt aaccaatacg ttctcgatat
    24181 ctgtagtcgg ctttttcata gccttcaata cgttcaagtc tgcgaagtag ataccgcaag
    24241 cacgtgcttt ctgggcttgt gtgttcaatt ccgaaacctt gctgaccggc aacataaaat
    24301 cagtattagc gacagagatc gtaacctcgc cggtagatac tttgtaaggc aactccgaat
    24361 ccggcatatc tttcaagaaa cgagtaacct cgtctttcaa ctcggcagta agcagacctt
    24421 tagatacttc tcctgcgata gctgcttctt cctctacttt ttgctcagcg gcgtcttgtt
    24481 ttttactgct gttgcaagat accattccaa atgtaatcgc tgctatggtt agcaggctaa
    24541 caaaactctt tttcatgtta ttctttattt ttagattata tattttgtca ttaatcgctc
    24601 cctttgttta aatacttgcc gggaaactct gcgaagatag atataattac caataaagca
    24661 aagattccta acattaataa attaaatgta aaagtagaaa atgtataacc ggcgaatttt
    24721 ttctcatgac tatagaaagg cgcacgtccc caattattgt ccggttccag ataaatctgc
    24781 ccgattttgg gatagatccg gttgtgagcc tccttataga attgggtact ggttgagttg
    24841 agtaccagct cctcgatggc tgagttatga tgttcctttt tcaaggtgtt caaccattcg
    24901 gagccgtgtt cttgaatgac ctctttccgt tttttctcta ataacgccgt gaaattatcg
    24961 ctacgggtat gcagggcttt ttctacttta tccatatagc tctcgtaact ctctttggac
    25021 gtataggggg cgatacgggc ggcacgggat agtacggcca gttcgttgtg gatcgtccgg
    25081 gtgttctttt cccgtttctc cgggatcagg ttgaggctgt ttatgaggct gcgcacctcg
    25141 tcagcatgga cattccggta atattgcgct aggaactttt ctttctcgac cgtgaaaaat
    25201 aggcggttgt agctgttgtt ccggaattgt tccgtaacca acgcctcgaa tgcccaacgt
    25261 gagggaataa cctcaccgat aaggggcact atgttccggc tggatgcgct tctgctcaaa
    25321 tcgtcgaact tgacaactaa gccgcaaagt aagatctgcg ggattaaaag cagcggtatc
    25381 gttatataga tcgctacgat cgagtttagg gattgcgata gtaccaaacc tgtcaggttg
    25441 gcgaggaatg aggttgccca tagcgtgatc caccaagtaa ggaacatctc gcttccaatg
    25501 cctatcaata aatttcctac cactatgaat agcaaacttt ggatcgctga gatacaaagc
    25561 aggtagaaca tctttgacga gagataactg cctcggctca atcgcaagaa tcgttctcgc
    25621 tttaggagcg tccggtcctt gatgatctct tcggcgctga tacttaatcc cgtgaaagta
    25681 gcgacaatca ccgccatgaa aatgtaggat accagatttt tgttcgccag caaagaatac
    25741 ccgtcatcgg gtacgaagcg ggtgagcagg gccacgatca ccgccaataa aggagtctcc
    25801 agtaaggcga tgcacaagta ctgcttattg gtcagcttgg tctttatgtt tctttccaag
    25861 aagatacaga attgcttcca gatcgagggc ttctgctgat gattcggggg caggggggta
    25921 ggcttaacct cttggaactt cgggcgggaa gctacatata actcatgcca ttcttttgaa
    25981 gttatcttcc ggatgtttgt ctggttcccg ctatcgtcta tcttttttgc gtcgataatg
    26041 gtcaggatta gttccggatt gatatttccg caggtgccgc aaacactgat atcctgatcg
    26101 gtgtaattgg cgatccgttt gaaataagtg atcgcctcga tcgggttacc gtcgtaaatc
    26161 gggtaaccgc cggtatctaa taaccacagg cgatcgaaca acttatagat ctcggacgaa
    26221 ggttgatgga tattgacaac cacgagccgt ccccggtgcg tttgttcctt taacagcatg
    26281 atgaccttct cggagtcggt ggacgagagg ccggaggtag gctcatccaa ataaaggatc
    26341 gccggctcac ggataagttc cagtgctata tttaaacgtt tacgctgccc tccgctgatc
    26401 gttttccgga ttggagaccc gacggccaaa tcccggatct tgctcagatc caaatcctcc
    26461 agtatcgtat tgacacgatc ctcgatctcc ttttcggtca ggtttgcgaa acaaaggcgg
    26521 gcggtatacc atagattttg gaatacggtc aattcctcga tcagcaagtc atcctgaggc
    26581 acgaaaccga tcaattgctt gcattccgga tcactcagcg gatgtccgtt caagcataca
    26641 cttccctcac cggggataat attcccattt aagatgctta acaaggtaga cttaccaacg
    26701 ccacttcctc ccatgatggc taccaactgg ccggattcaa ggttgaaaga gaaattgtgc
    26761 ataccgttct cgctattctt gaagctgaac tcgatatccc tcccggttaa taaaatacgt
    26821 tccttatgct cattctgatt gaatacatcg aggacatcac tataataaac cggcaagaat
    26881 agtgggcttt tgattacgct gctgcgttgc cagccataga agataccgga agtaagcggg
    26941 atatcgttca tgaatacccg tccgctgcct tggtagataa agaccattcg gtcgaaccgg
    27001 gtcagtctca acacccgtat ctcgccctcc aacccccttc tgtagatatg gttgacgtct
    27061 ttatcgctat catcagcgtt gatcgtaagt atggaggggg attttttacc gactacaaag
    27121 gcgtataggt tgtcgaaggt atccgtatcg atattgaata tcgtagcgat cttatggaaa
    27181 atggctaagt tctcgttcaa tccttcattg ttgccatggg cgaactccat gaaacggaga
    27241 agaagcaata gttggtcttc cgcgatcaat ttgggcttga gctggttgca tacgttaata
    27301 ataacgcttt ctctatcgat gtcgaactcc gggtcatcgt aaacactttg tatctcttca
    27361 aatagctcca tatattcttt atgggagcgg ataccaaagt gactggttaa gtaagaattg
    27421 acagcttgac gtgcttgatc actttctatt tttgccaagg acgcaaatat agcgaacaag
    27481 tttagtagcc cattgagtat agtttcattc attcatcaaa gtattgtttc aaatgtcttg
    27541 caaagataag gtaagtgaaa caaaaaacag gtcgaatgtt agacttttta agcggtcaag
    27601 tgaataacat gatcaataat tgggcagaaa tcacccggat gaacatggat aacgggtaaa
    27661 ccgtagcgta agatacggaa ggctcgtcac cctcgacggt cgtattggca taactcaagg
    27721 ccatcggatt ggccatgctt ccgcatagca tacctatgtt gtgggcgtaa tctaacttga
    27781 agaattgcga ggcgatgaac ccgacgatca agaccggtac gatcgtcaat aggaaaccga
    27841 gaccgatcca taacaatccc tcggcacgga agacggtctc gaagaaatga gctccggagt
    27901 cgattcccag tcccgccaga tagatcacta taccgaactg ccgcatcatc aggtttgcgc
    27961 tctgggtggt ataagtcgtt aggtggaaac gggggccgaa cgcacccatc aagattccaa
    28021 cgatgatcgg tcctccggcg atacccagct tgatgggggt actcattccc ggtatggcga
    28081 ttgggatcgc cccgattaat acgcccagcg taagtcctac gaatatggca agcaggttgg
    28141 ggttatccag ccgtttcagc tcgtctccca atatcttacc cacgttattc acggaattgg
    28201 cctcgcctac gatcgttagt ttatccccaa tctgtagacg gaggtcacgg gaggccacca
    28261 gatcgatacc cgcacggttt acccgggtga tgttgatccc gtataggttg cggagccgga
    28321 gcgagcctag ctttaccccg tttacccggt tgcgggttac gacgatacgg cgggagatca
    28381 attggctgtc gatagcgttc cagtcaatat cttccttatt ccagtccgta gtctcttgtt
    28441 ctccgaaaag taccttgatg gattcgacat ccgcctttac ggatatgata agcaaatggt
    28501 ctttttcctt taagatggtt tcagaggtag ggatcgtcac ctttccgttc ctccagaggc
    28561 gggagatcac gaaatgtttc tctgtcaatt tcatgacttg ctggatgctc ttattgtaaa
    28621 tagaggggtt taatacctga aattccgcta cgtttgttgt cgtgtcttgc tccttatgcg
    28681 tgctctgtgt cttttttgcg aataaggacc tcaagatgat aatagcgaga attacgccta
    28741 cgacacctaa tggataagct acggcacagg ccagagccat atccgttacg ttcctcgtat
    28801 tttccggatc catttgtaag agcgcttgct gggcggcacc tagggccggg gtattcgtta
    28861 cggcaccgga tagcaaccct accataacgg ggacggaaat tcctgttatc caatgaaaca
    28921 ccaacgtcaa aatcagtcct aaagcgatca cccctaatcc catcgtattc atttccaccc
    28981 cgcctttttt tagggaagag aagaaaccgg gacctacctg caatcccaag gtatatacga
    29041 aaacgataag cccgaagttc tgagcgaagt tcagcatgtc cttatttacg gtaatgccca
    29101 gatgccctgc cataataccg gcgaagaata caaaagtgat gcctaatgaa atgccgaata
    29161 tctttagccg ccctaaatac acaccaaccg ccgccacgat agaaatgacg gccacggcct
    29221 gtatcatcga gggttctgta agcgtctcaa gtaaccaatt cataagagtt tcttttttgc
    29281 tttagaagcg caaaaatata taaaacaaag caattaaaaa aattgtagta tctttgccca
    29341 cgaaataacg atgatacagg gtgagggaaa cgatggttaa atatataaag tggttgctgc
    29401 cggtactttt tattgcgtat tatagcagtg tctcgctttt tacgcacgtc catgtggagc
    29461 atggtacgac catcgtgcat gcgcaccctt tcaagaagac ggcggacggt acttgccatc
    29521 atcatacctc tttggcggag atacagttgt ttcatatgct ctcatctatt cacgtgatgg
    29581 acggggcgat tcacctgtta cgtttacaat tctattcttt aaaaatatct aatctctctg
    29641 agtctccggt ctatccggat catgtcactt ccgttgaggg actgcgatac ctgcgggctc
    29701 ccccagttgt ttgattacat atccagaaat caatatccgt ttgtagagac ggggcatgcc
    29761 cgtctcctcg gcaattcgta atcattaata ttcaaacaac tattaatcaa gcaatgaata
    29821 agttcattac acttatacta tgcctgtgct gtgtctttac atcagcgtgg gcagagggag
    29881 acgatcatac ctccctgaat ccttccgacg ctaatatcgt aggccatatc ctcgataaga
    29941 aaacaggaga gcatctctct tttatcaatg tctacctcca cggtacgacg atcggtacga
    30001 ccaccgacgc taccggtcat tactatatga agaatcttcc cgagggaaaa tacaccttgg
    30061 tcatgaagtc tatcggatat aaaaccgagg agaagacggt gacccttaag aaagggaaga
    30121 cattggagat caatttcaat gccgaggaag acgctgtctc cttggacggt gtcgtcgtat
    30181 cggcaaaccg taacgagacg acccgccgtc tggctccttc tttggtaaat gtactcgact
    30241 ccaaggtgtt cgagactacg cacgccactt ccttggccgc cggtctgaac ttccagcccg
    30301 gcgtgcgtgt ggagaataac tgccagaatt gcggtttcca acaagtacgt atcaatggtc
    30361 tggaaggccc ttatacccag atattggtgg atagccggcc gatcttcagc gccctgaccg
    30421 gcgtatatgg cttggagcag atcccggcga atatgatcga gcgggtagag gtgatgcgcg
    30481 gaggaggctc ggccttgttc ggctcgtccg ctatcgccgg tacgatcaat atcatcacga
    30541 aggaaccgat gcgcaactct gcccagattg ctcattcgtt gacgatgatc gggggaagcc
    30601 gtccggataa taatacgacc gtgaacgcct cattggtgac ggacgatcat aaggcgggta
    30661 tctacctctt tgggcagggc cgccaccgtg cctcttacga ccatgatggc gatggctact
    30721 cggagctggg taagctggag gcgaagaccc tcggattccg ttcctacttg aagaccagca
    30781 attattccaa gctgactttc gagtaccata acatcagcga gttccgccgg ggcggtaatt
    30841 tattggatct tccgcctcat gagacggata tcaccgagca gaccgaccac cagatcaacg
    30901 ggggaggcct gaaattcgat cttttctctc gcgactacca tcatcggctg aatgtgtata
    30961 cctccgccca gcatacgaaa cgccagagtt attacggtgc cggaaaagat ccgaacgcct
    31021 atggtaacac gacggacatg acctttatcg gtggcgccca atattcctac gaatgggata
    31081 aatgcctttt tatgcccgct acctttacgg gaggcgccga atatagctac gatgatctgc
    31141 aagacgagat gcttggctat caccgtacga tcgcccagac cgtgcatatc ggtagcgcct
    31201 tcgcccagaa cgagtggaag aatgaccgtt ggagtttctt gatcggtggc cgtttggata
    31261 agcataacat gatggatcat gtgatcttta gccctcgtgc gaacgtgcgc ttcaatccga
    31321 cgaaggatat caacctgcgt atgtcgtact ccagcggttt ccgggcccct caagcgttcg
    31381 acgaggattt gcatatcacc gccgtggggg gcgacgtggc gatcatccag atctctccgg
    31441 acttgaagga ggagaattcg cagagcgtga gcgcttccgt ggatttttat catcgcttcg
    31501 gcccggttca agtgaatttc ttagtggaag gtttctatac ggatttacgg aacgtgttta
    31561 tcttggagga gatcggccgt gacgaggaca ataacctgct gatggaacgc cgtaatggaa
    31621 agggtgcccg tgtgatgggt atcaatctgg agggtaagat ggcctattct tggatgcaga
    31681 tacaggcggg tgctactttg caacggagcc gctacaagga ggcagagcaa tggagcgaga
    31741 acccgaatat caccccgcag aagaagatgt tccgctctcc ggacgtatat ggctatttca
    31801 cctctacctt cacgcccgtg aaacgtttct ccgcctcatt gacgggaacc tatacgggca
    31861 gcatgttggt gcagcacttg gcgggttaca ttcccgagga tcgtgaggag aagactcgtg
    31921 atttcttcga cttgaacctg aagctgtctt acgacttccc gatcttcaag tccgcaacct
    31981 tgcaggtgaa cgccggaata cagaatatct tcgactccta tcaagatgat ttcgacaagg
    32041 gagcgcatcg ggatgccggg tatatctatg gcccgggaat tcctagaagt tatttcgtgg
    32101 ggtgcaagat cagttattaa atactcggcg agccttgccg agggagttgg aaggactttg
    32161 aagcatccgg cggctatcgc cgggggatgt ggaagactct tgggatgccc ggcggggggc
    32221 gccggaggat cggaagggaa ctcaagatgc ccggcggaga tcgccgcaga gttccaaccc
    32281 gtttccaatc ctccggcgag cctctacggg gctattcctc cactatcctc tctatataat
    32341 tcggcggcag ggtggtgcgt ggtactttca tgccgccgaa ccatttatgc aagggcaagt
    32401 cgaagcctgt tccattcatg taattgtaga gggaaacgcg aagcccctcg ctgaaaagct
    32461 ccggatcgca gccggatagc gcctcgaact gtacgtcatt acgggcgaat ccgccaaagg
    32521 gaggctccgt gacacggcaa ctgtactcgg cggggtgcaa ccccacaggg ctatgcgctg
    32581 tcatggcgaa acgatgccaa aatccggatt gaatcagccc aagctcaaac atttgccgga
    32641 ccgtttctaa ggaatctatg gtttcttgag cggtttgggt cgggaaacca tacatcaaat
    32701 aggcatggac catgatgcct gccccggtaa agttgttggc gacccgtgcc acttgagcca
    32761 ctgtcacccc tttatttatc agcttgagga gtcggggaga ggctacttcc agacctcccg
    32821 acacggcgat gcagccactt cgttgaagaa ggtcgcatag ttcctcagta tagcttttct
    32881 caaaacgaat atttccccac cacacgacgg ttatcccacg gcggataatc tcctgcgcca
    32941 tttcccgtag caaggcgggt ggagcggcct cgtccacgaa atggaagccg atctcgccgg
    33001 tttgctcgat caagcgctcc atacggtcta ccaaagtctt ggctgtattc ggctcatatc
    33061 gtttgatgta atccaatgag ccgtcacaga aggcgcattt cccccagtag caaccgtgcg
    33121 ccaaggtcag tttattccag cgaccatcgc tccaaagctt gtgcatcggg ttggccattt
    33181 ccatgacgga gatgtatttg tccagcggca agccctcgta atccgggaat ccggtctcgt
    33241 tttgccggca agcggggtaa gcggggttat cttgataaac gacccggctg ccgctctcgt
    33301 ccaaggagaa ggtgcgtacc agttcctctt tggggatcgc cccgtctaga tagcgtaaca
    33361 cttggaagag tgggtcctct ccatcatcta gcaagaggta atcgatatat ttgaagaaac
    33421 gtgtatccgt gatggagcga agttccgtat tcacgaaacc acctcccata aggatcggga
    33481 tatcgggatg tgcctgccgt agccattggg cgagccggag ggtactgaat aaattccccg
    33541 ggaaaggtac actgaaagcg atcgccttgg gcttgctctc ggcgatgtgc ttttccaata
    33601 gcggttgcgt caggcggtcg ataaagccga aaggtttttg gagggcttcc tcgatctcgt
    33661 cgaaagagga ggcgcagcgg cccagatgct cggcatatcg actgaagccg aaatccgggt
    33721 cgatcgtttc cctgatcaag tcgcagagat cctccagata caaggtcgcc agataacggg
    33781 ccttatcccg taatcccgaa gtgccgaacg cccattccag ctcctcctcg ttttggctcc
    33841 cgcggtcgct ttcgggaagg taatcttggt tacagatgcg ataagcgaga ggatcgttct
    33901 ttccctgaag gaaagcgacg acggcggcta tcgtgtcgat ataccgttgc ttattagcta
    33961 gcatcccccg gactttagcc ggatatttac ctttccgtcg ctcgatctcg gcgaataact
    34021 ccccgagacc ctgcgtggaa aacaaagcca agattgtctc gatacccaga tcggtctgcc
    34081 cggcatgtac accctttgcc tccaaataac cttttaggta agccgtggaa ggataaggcg
    34141 tattgatctg cgtaaacgga gataaaacca gaagaaccga agctaatccc atatcaactc
    34201 aactaatttt caattattca agctattgtt gatagactcg atatagtcca gaatctcatc
    34261 ccgtccctct ttcttctccg aggaagagag gaagatcgga ggaagctctt cccaagtctc
    34321 cagtaattta tccgtataga cttttaggtt ctctttcaag cgtcccttgc tgatcttgtc
    34381 gatcttcgtg aagatgatag agaaaggaac cccgctctca cccagccatt ccataaactc
    34441 cagatcgatc ttttgcgcct cgtgacggca gtccaaaagg acaaataggt tggtcagttg
    34501 ctctcgatcg aggatatagt tctcgatgat acgtttcaat tgctcccggt tctccttgcc
    34561 tcgttgggcg aagccatacc ccggaagatc taccagatac cactcgttat tgataagaaa
    34621 atgattgata agtaaagtct tacccggtgt ttgcgaagtc atcgccaagc ccttcttgtt
    34681 ggtaagcata ttgatcaaag aggatttgcc tacattgctt cgtccgatga aggcatactc
    34741 cggcttatta ccctcggggc atttccttac gtctgtgttg ctgataacaa attctgcgct
    34801 tttaatttcc ataaaatata aattaatgaa taatgagtat tgaataatgg ctaggcttaa
    34861 ttctcaattt tcaaatttcc attttcaatt gccgaaagcc acagcccggc gaacgtgatg
    34921 cctccgttta ccataagcat ctcgtagccg aacgtatagc ctgcgtattg tttcaccaag
    34981 aaatccgtgg cgaggcaaat caacggggag gctatacaga tatagggcac gtatttgtca
    35041 cggggtttcc gcttcgtgaa aagcccgaaa acaaacagcc ccaatagagg accatacgtg
    35101 tacgacgcta tcatgtagat tgcgtcgata acactccggt tatttacggc cttgaacgcc
    35161 aagatgatca agacgaacaa gacggatatc atcacgtgta cctttaggcg ggtacgtttc
    35221 gcccttttcg cttcctctct ctgcacgccg aggatatcca cgcaaaaaga ggtggtgagc
    35281 gctgtcaacg ccgagtcggc gctactgaaa gccgccgcta tgataccgat cgtaaagaag
    35341 atcaagatac tcccgcccaa gatccctgag gtacaaaaca tcgggaggat atcgtcgttg
    35401 agggttggca actggatgtt ctgctgtgcc gccaatgtca gtagtagtac ccccagcgcg
    35461 agaaacaaga agttgaccgg cgtgaaggcg aagccatatg tgtacatatt cttctgggca
    35521 tccttcaagc tcttgcagga gaggttcttt tgcatcatgt cctgatccag cccggtcatg
    35581 acgatcgtga taaagatacc gctgaagaac tgcttgaaga agttttgcgt actatgccaa
    35641 tcgccaaact cgaagatccg gaaatgagga ctttccacca aggtctgcgc catacccccg
    35701 aaatccagtc ccatcttgtc cttcacctgc cagatgatca cgatcaacat tgccacgaga
    35761 caaagggcct gcaacgtatc tgtccagatg atcgtcttga taccgctccg gaacgtatat
    35821 agccatacca gcaggatact gaggatagcg gtcacggcga atgggatgtt ccaagcgttg
    35881 aacacgtagg tttgcaagat caagaccact agatataagc gtgcggccgc ccctacgatc
    35941 ttcgagagca ggaagaatga ggcccctgtc ttgtaccccc ttctcccgat ccggtcatcc
    36001 agatacgagt agatggaggt aagctgcaac ttatagtata gcggtagcaa taccttggct
    36061 ataatgatat atcccacgaa gaagcctaat acagtctgca tatacgtcat atcgatcgcc
    36121 cgcaccatgc cgggtaccga tacgaacgtc acccccgata aggatgtccc taccataccg
    36181 atagaaacga tataccaagg tgatttcctg ttcccgagga agaatgcctc gttgctgtta
    36241 ttacgtcccg tgatccatgc tatcagcagc aagacggcga aataggcagc gataataaaa
    36301 aggatcatat agctgttcat gtattgctaa cttctttctt cttctccgca aagatacggc
    36361 tttactttga aataaccggc atatgcgtgg attctaccgt gatgggtttc ttgaagccct
    36421 ttaggtagtc catgaaagcg tcagtcgata tgatacctaa attgtcgaat tccgggatct
    36481 cgtagccctt gaataaagag gcgtcgtacc cgtctccgcc atcggtgatg aaagcgtcta
    36541 gggtcaccac gcaagaggta ttgtcctcga tctcggtctt ttgcccgtct ctcgtataga
    36601 ctattttctc gatcttattt ccgcttaggg taagcgtgag gtcggaggat tgaaggaaac
    36661 cgttcggatt cttccgtcca tcctccaata gcttcttcaa ccgcttgccg tcgaaacgat
    36721 aggcaacgat agcggagccg aaaggcaaga tgttgccggc acgcagtcgg gtgatatccc
    36781 ctttcgggag ggccgcacgg atacctccgt aatggtttac gccgatcacc ggctgatcct
    36841 tgtaagcggg catctctttt tggaaacgct gggcgtaagc ggccgtgacc aacgccccga
    36901 taggcgtata gtcgaactta ttgatggtac ggtcgtggat caaggcctct tttgccgtgg
    36961 caagtttctc gttcagccga tatttatcca tgatcttctc cacggcctct cgcatctccg
    37021 ggttctcctc gcaggctaca cgcacggtat ccccttggat gaaagagata tcccggtgtc
    37081 cgttgaaatc ctgtatctgg aacagcagtt tcccgatatg ggtaccgttt acgccggctt
    37141 ggatgatggg aatgttattg atcttatcga gcaccagctc atgcgagtgg gcggatatga
    37201 tggcgtctac cttatcgatg aacggcagtc cttgggcgtt ctcctcggtg atgcggtaag
    37261 gcattttcat atccgtgccg atgtgcatca agaggataat catatcgatc tggtcctctt
    37321 tctttaactg gtagacggtt tgtatgcaca ccgctcccag cggatgcgtg aactgaagcc
    37381 ctttcaggtt ctccggcttg gtcttgacgt aggtgtccgt cgtggtcagt ccgatgaagg
    37441 ctatgcgcag ggaggagcca tctttcaact tacgctctac gatacggtag ggactcaacc
    37501 agttggggtg agtatatctc ttctcttcgg tgatattggc ggccacatgg gggatattca
    37561 aggcggcggt gtccactaga taagaaagtc cccagtcgaa ctcgtggtta ccgatggcgg
    37621 acatttccac gtccatcgcc tcgtacattt ctttgatagg ctcgcctttc gtgatcttgg
    37681 agaaatagct tccgctgaaa ttatctccgc ctgagacaac gatggaatgc ggatagcgtt
    37741 gtttctcgtt ttgtgtcatt tgtaccaacc gggcggctcc cggcgtgatc ccgtcggagg
    37801 cgaaagcccc atgaaaatcg ttgaatgaga aaatggctaa agtgtctatc gagctggacg
    37861 gggtggcgat atcttgtgcg aataggggag cggttagtgc gctgcctagc aaaatcgctg
    37921 atacgaattg ttttttcagt cccatggttg tatgtattaa tagggacaaa agtaggaaaa
    37981 ataacgagat tcaccgagga aaacgcccga ttcgtcgaat tctttttgat cgttttaaac
    38041 cttcggccta cctttgtgtc atagtaatag ctcgtgagag tgaaagcgaa ccggttgttc
    38101 atcataaccg ggaaataggt aaacattaag tcaaagggcc gccgtccgga taagatgcgg
    38161 cccttttgat ttattcggac ttgaggttgt ttacgggatt gtcgtgggtg gtacggaata
    38221 cgttatatcc ggaaaccgcc agtatgacgg tgagtaccaa tacgcctcct cccacgaata
    38281 gataccagga tagctggatc ttttccgaga attgttcttg ccatttttgg gagatataga
    38341 aagcgatacc gcaaccaagt aagatggccg gcaatgctat ggtgatgata tctttcaaga
    38401 aaatatggag tatgtctttt accgtggctc cgttaatctt acggatcgcc atttctttcc
    38461 ggcgacggtt cacctcgtcg ttcgtgtatc cgatcaatcc gatgaagacg atcagcaagg
    38521 tgacgatgcc accgatcatg acggaatcac ggaatttccg ggaggaggtg tatccttcca
    38581 gcatctcgct cttgaaggag atcacgttga gttctttatc cgggatgagt tgccccatta
    38641 gatcctgtgt cttgcgtagg gcctcggaag aaaggctatg gtaccgaatg accatatgtt
    38701 gggccgcccc tttcgtatag aacatgatct tggctcgcgg atcttctccc gctatggaac
    38761 ctaggcggaa atcctcgaat acgccccgga tcgtgaagag aggcatcgac tcggacttgg
    38821 tatcgtgtcc ggttatttgt accgtcttgc ccacggctcc atccttccag tcggcgaaag
    38881 gtttcatgta ttcaatgaaa ttgcggctca ccagtatctc ttgcgaggag gtggtattct
    38941 cggtgaagta ctgtccttct acgatcggga tttccaatac gttcaggtaa tcgtttccta
    39001 cgtcgtagag gtcggcgatg ttgaatagtt cccggtcgtc tcccggaaga tagacgttat
    39061 tgcccgaggc tccccagaaa ggaaggttat agcaagtcgt gatggcgtct acctcgggca
    39121 atctctgggt ttcctcgatc agtttggcac gccccgtgga gtctacggca ccgatataca
    39181 cataggcaag attctcggga ttgtatcccg gatgatcatt caccatatgg tcgtattgct
    39241 tgcctaccac tagcaataag gaggcgagga agctgattgc cgtgaactgg aagaacaaga
    39301 gtcccaattt ccaaaggcgg cgtgcctcac ggatgctccg gaaaacagcc gctacaggaa
    39361 tgcgtcctaa gaaccagccg gtagctatgc ccgtagagat cagtacgact atgaccgtga
    39421 ggcatatcgc ccacataccc gtggatagga ataacgatcg gactcccgtg ccgatcagct
    39481 cctttataat tccttgaaat cctaggatca aaagtacgac cagcgctagc gcgacggtga
    39541 cgtgggtccc tacctcggac aacgccatac cttggatatc cttaccgctc gccccgtaac
    39601 atttgcgtac ggccatctct ttcgtgcggt tcacgatgga ggagatcacg atcaatatat
    39661 agttcattac ggcggtgaag atcaatacga aggcgatgaa cgagaggatc aaggccatac
    39721 gtttggccat atcgtcctcc atatgtacgt tgagtagttt gtggaaggtg aaggtcagtt
    39781 ccacgccggc tttcttaagg tcgtttacgg ggaaatgctt gtcgatcatc tgtctcattc
    39841 ccgcttccaa ttgggcctct gtcgtacccg gcgatacctt gacgaaactt tggtaacggt
    39901 cgtttccggt taacatatgg gttccgtccc acatgaactt gctgatggag gaaagggata
    39961 cgataatgtc ataactctgt tcggtgttgt ccggtagttt cttgaatacg ccgcctatcg
    40021 tgagggcttg tcccggtgcg tcgtcaatct cgaagcgttt tcccatcacg ttaccgccga
    40081 tacgttcggc gatctcgtcg gatacgagca cgtacatggg ttgggagaga acttgcttag
    40141 ggtctccgat gagcatgggg cggggcaata cgtcgaaaag acaactgtcc gctaggatga
    40201 aggtcgcttt gagccgatgc ttgttgtcgg acatcgtaaa aggggagttt ccccggaagt
    40261 acgtatagcg tgtggcggcc tcgatctctg gtgtctcttg tttcaagagg gggattactc
    40321 cggcgggcgt ttgcccgtgg tcgcccactt ccccgttcat gaaaaatttc tcatatactc
    40381 gatagatccg gtctccgttc ggatagaagt tatcgtaggt gttctcgaag tggactttag
    40441 cgatcagcac caagccgatg gtcagtccta tacccaagga gataatcttc attacattgt
    40501 gttgccctct cttaaaaagg gagcgaattg cgatcccgat gtttttcata ttgttattgt
    40561 attattttct ggtaagataa aatcaaatac cgtgccattg tgtttatgtg gttgaaaaac
    40621 agaggggtga gtggcgtacg attgtttatg agtgtccaat aattggacaa gggtgtccaa
    40681 aatctggaca cccttgttta ataccttttc tcaatagagg ctccggggaa ataatgcgtg
    40741 aggattttcc ggtacgaata tcctttggct cccatcacgg cggctccgat ctggcaaagc
    40801 cctacgccat gtccccatcc ggctcctgtc aagatgaagc gggaggggat atcaaggcgg
    40861 atatccttct tatcgacaac aaaggccgag ctgtataggt gcgtctcgga taatgtccgg
    40921 cgtatctcaa gctctttgcc gatggtgaac gaacggcgta cccctacgat cttgagtttc
    40981 gtgatgcgtc cggacgaacc tctttccaac ggtatgagat cgatgatcgg cccgaaatcc
    41041 atacccgttt tccggtggat caaccttgat agttcctcct gcgtatattc taccttccaa
    41101 cggtagaaat ccgtggtctc ttgatcgtag ttgtttagca cttggctaag gatctccttg
    41161 tccgttgtat tacagaaggc ttcgggtgag gtacgtatcc attgttccgc ttcccgctcg
    41221 tccgtcaagt cgggatagga gggaatctcg tcatccctca aggcggtaag ataggagtgg
    41281 ggaaccggtt cccagcaatt ctcgaatttc tcggtcacgc ctccgcagca tttcgagaag
    41341 cgggcgtcgc agatcgtatc gttatccatc aatacctctc cacgtgtctc tttgatcacc
    41401 tccctgacta tcgggttcga tgcccgggta ataccttggt aacgctggca atggtcgtcg
    41461 gcacagacat cgaacagatc atggtcctcc cggtcgtacc agcggatcaa ggtctcgctg
    41521 tcgcggtaac aacttttata gggcgtaacc gatccgttca agttgaaatt cttctcgacc
    41581 tgcgccaaga gccagcttcg cgagatcacg gcatgggctt tcagcaactc tttggaagcg
    41641 ttggcgctca tctccgagga gattacgctg gtaaggtatt cctccacgtc cacttggttg
    41701 atcgtgacga tacctttatc ggtcgccacg aggttcaacg ctcccttgaa gcgttgatcc
    41761 tcctgtcgtt gccagtgaaa atccacgccg atcgtgaccg ccttcaagtc gaaagaggat
    41821 tgcgggctgg tcggctcgaa gaatagctcc tgataaagct tcccattgta cacgatcttg
    41881 ccgtttaccc agagggcacg ttgctcgcct atggtgaacg tgccggtttc cgtatgtaca
    41941 tactcctcgt taaaaacaaa tgagattgct ttgtgggtca tgattcccac attgattaca
    42001 ggtgcttcca tatccttatt cctttattct attctttttt cgcgttcagg gaattaaatg
    42061 tgaggtaagc gatcatgaca aggtacatga caaccgccag tatctcggcg gcattgctag
    42121 atgcccattc ctcgttcatc aagttgattc cgccgaaacg taaggccgcg ctaaccacgc
    42181 ccatcaaggc accgccggcg ataaagccgg aagccagtaa cgtacctttc tccaagcggg
    42241 ctgagttcaa gctttggtct ttgctacggc ttcccacgta ccaactgatc gctccaccga
    42301 tcaaaagcgg cgtattcagg tccaaaggga taaacatacc caaggcgaat gccaacgctg
    42361 gtatcttgca gaagttcaat acgacggcga ggacggctcc aatcgcgtat aaagcccaag
    42421 gtgcccccga gccactcatc aacggctcga taacggcggc catagcgttc gcttgcggag
    42481 cggccaattg tccggtcgtg aaaccgtacg tctggttcaa tatcaagatc acgcctccta
    42541 ccgtagcggc ggaaactagt gtgcctagga atttccaagt ctcttgcttg gcgggcgtac
    42601 tacccagcca gtagccaatt ttcaagtcgg taatgaaacc tcccgccatg gaaagcgccg
    42661 tacaaaccac gcctccgata atcagggcgg ataccatgcc ggccggccct ttcaacccta
    42721 cggcgaccaa gatgatggag gcgaggatca acgtcatgag cgtcatgccc gataccgggt
    42781 tcgtccctac gatagcgata gcgtttgccg ctacggtcgt aaacaggaaa gcgatcaccc
    42841 cgaccagcaa taagccgatg gcagcatgga accaattatg aagtacgccg aactggaaga
    42901 acaggaaggt gacaatcagc gatacgatga taccgatcgt tatcactttc atcgacaaat
    42961 ccttttgcgt acgtatagta ttactctcca cagcgtctcc ttttcctttc aactcgttcg
    43021 ccgccaagcc tacggctccc ttgatgattc cccaagagtt gatgatgccg atcaccccgg
    43081 cggtagcgat acctccgata ccgatgtggc gggcgtaggt ggtgaagatt tgctcggcgc
    43141 tcatgctccc gacggtcgcc gtgatagcgt cattgccgaa cgtaagtacg tcggcgctga
    43201 aaatggcgga catggcgggg atgatcacca gccataccaa gaatgaaccg gcgcagatga
    43261 tcaaggagta ttttaatccg atgatgtaac ccagacctag cacggctgcg cccgtattga
    43321 ctttcaacac gatcttggct ttctccgcca gcatctcgcc ggccccgacg atacgggtac
    43381 tgatcgtctc gccccaccaa ccgaaggtgg cgatgatgaa gtcgtacaaa cctccgatta
    43441 atccggcgaa gatcaagggc ttcgcttggc ttccgccttt ctcgccggag acgagtactt
    43501 gcgtggttgc cgtagcctcc gggaagggat acttaccatg catatcggat acgaaatatt
    43561 tacggaacgg gattaatagc aagatcccga tgatacctcc taacaaggaa ctcatgaaaa
    43621 cctcgaagaa attgaccgtg atctccggat atttgtcttg caggatataa agggcgggca
    43681 aggtgaaaat ggcccccgct acgatcacgc cgctactggc cccgatagac tggatgatga
    43741 cgttctctcc caaggcgttc ttccgcttga atccgctaga caaccctacg gcgatgatag
    43801 cgatcgggat ggcggcctcg aatacttgac cgaccttcag gcccagataa gcggccgccg
    43861 cgctgaatat caccgccatg accaatcccc aaaggacgga ccaaggcgta acctccggat
    43921 agtgtttgtt gggagacata agaggcttgt agctttcccc ttcttttaat tctcggtagg
    43981 cgttttctgg cagcccggtt accttttctt cattttctgg tttcacgata ttaaaatgtt
    44041 agattattag ttcgtaatag ctccaccaaa cgggtgttgg gtgacaaatt tatgttttct
    44101 ggctgagaca tgcaaggatt ctttagaata gttagggcaa ccgtacccaa attatctata
    44161 tgaattctta cccagtagcg tatgaattct tgttcgcatg ctgtataatt ctataaacca
    44221 cggcgtgatc tgtacagacc aagtcgtgga atatacaaat cacgtcgtgg tctgtacatc
    44281 ccacggcgat catttggaaa tagatcaagt agcaagtatg tttgtatatg gcaaaaagaa
    44341 tgtttattac ttgaggacat gaacaattat acctagagca gttatagttg tacatatcaa
    44401 gcaagagatg tgcgacttga atgggatggg ggagaagccg agtaaataat ttgaggttta
    44461 tcgttaattc gtaaattctt tctatttttg tagtcaaata cagaaagtag atgaatcaaa
    44521 gatatccttc agccttgttg gaaaatgccg tgaatgaatt ggcttccttg ccgggggtgg
    44581 ggaggaagac agcgctccgg ctagcgcttt atatgttgcg ccgggacgtc ggctatacgg
    44641 aaaacttcgc cgcggccttg gttgccctcc gtcgagacgt gaagtactgc aaggtctgcc
    44701 ataatatatg tgatgatgag gtttgctcta tttgcgccaa ccccagccgt gaccattcct
    44761 tggtttgcgt ggtagagaat atcaaggagg tgatggcgat agagaatacc gggcaattcc
    44821 gtggcgtata ccatgtgttg ggcgggatca tctcgccaat ggatggcatc ggaccgggag
    44881 acttgcgtat cgacagtctg gtgcgacgtg tggccgaagg tgaggtgaaa gagatcatct
    44941 tggcgttgag cactaccatg gaaggcgata cgactaactt ttttatttac cggaagctat
    45001 ccggttacga tgtgaggatc agtgtcatcg cacgtggcgt gtctatcggt gatgagatcg
    45061 agtatgccga cgagatcacc ttaggacgat ccattatcaa tcgtactgag ttcaatctca
    45121 cctcttctaa ttcataatca taactcataa ttaatatccg gaatgaccta cgaagaaacc
    45181 aagttgtccg ttatcatcgt taactataac gtgaagtatt ttctggagca atgcctctat
    45241 tctgtccgtg ccgccgtaac ggggatggac gccgaggtgt tcgtggtgga taataactcg
    45301 acggatggat ctgtcgaata tctccggcct aagttcccgg aagtggtttt catcgagaat
    45361 aaagataatc ccggtttcgc caaggccaat aatcaggcga tccgtcagtg caccggggaa
    45421 tacgtgttat tgctgaatcc cgataccgtg gtgggagagg agagcctccg cagcctgtgc
    45481 ttccagatgg atgaggatcc ggagatcgga gctatcggcg tgaagatgct gaatgggcac
    45541 ggggtattct tgccggagag caaacgggct ttcccttcgc cttgggtgtc gttctgcaag
    45601 atattcggcc tttcaaagct gtttcctaac tctccggcat tcgcacgtta tagcctgccg
    45661 tatctggata aagagcagac gcataaggtg gaggtgctgg cgggtgcgtt catgttgctt
    45721 cgccatgagg cgttggataa ggttggcttg ttagatgagt cgttcttcat gtatggggag
    45781 gatatcgatt tgtcttatcg gatcgtgttg ggaggctata agaacttgta cgtgccggaa
    45841 cggatcctgc attataaggg ggagagtacg aagcatggtg acttgaggta cataagggct
    45901 ttttacggtg ccatgttgat tttctataag aaatattatc cgggagccgg ttggttgatg
    45961 cggatactga tccggttagc tgtcctgctg aaagcttgct gggcgatgat ttcagcccct
    46021 ctacgcaaga aggctaaagc ggttaagcat cgccgccttt tgatcttgtg cagggaggat
    46081 cattttgagg aggtaaaggc cgtttgcctg aaagctatgc cggatctgga attcgtgaat
    46141 ctctgggatt tggacgtgga gcgtgtgatg gatgctatct gtcgcaagaa ccagatgaaa
    46201 ggctttacgg actacgcttt ctgcttcccc gatgcccgct atgagcagat gctcttgttc
    46261 atggacaagc tcgtgaacaa gaaagcggtt ttccatatat atacgaagaa gagtggtcgg
    46321 cttgtttaag taatccttga gtaaatatgt tgttgtcgaa tgatagagtc cgtttgaggg
    46381 cattggaacc agaggatctg gagttgttgt atcgttggga gaatgatccg gagttatggg
    46441 aagtagggaa taccttggcg ccctattccc gttatatatt gaaggaatat atagcgggta
    46501 gcgaccggag tatctatgag tctcgccaac ttcgcttcat gatcgaggaa tgcgatacgg
    46561 ggacttccgt ggggatcgtg gatttattcg attttgagcc gcatccgaat cgggcggctt
    46621 gcggtattat gctggaccgt aggtatcaag gacgtggctt cgctacggaa gcgttaaggc
    46681 tattgatgga atacgcttat acgtttttga agcttcatca actttatgtg catattcccg
    46741 tggcgaacga gcctagcaag aaattattta cccgtctggg atttgtcgag gcggggacgc
    46801 ttaaggactg gatcaggaca ccggatggtt attccgatgt ctgcataatg cagttaattt
    46861 aaatacgggt ccttcggata ttttgtccaa gttttataat cattgcctaa taattctacg
    46921 gaatctttcc aatagccctc cccgtcggca gacaagatat tatcggtggt gatatggctt
    46981 acggcccacg agttccgttt gatttcatgg tttaattgcc cttcggtcca tccggagtat
    47041 cccaagaaaa acttcacttt cccattgatt gggtgcccgt tgaggatgta tcgtttcaat
    47101 gcgttgaaat ccccgtcgaa atataaataa tcattgatct ttaatgcgtc cggaatgata
    47161 ttatccccta aggaatgaat aaagaacaaa cggttggggc tgaccggccc ccccagataa
    47221 atcggtatct ccggaaattc ggcaaactcc ttgaaaaaag agtttacgat aagatccgtt
    47281 tttttattca agacaaatcc catcgatccg tgttccgtat gctctattaa taatacgacg
    47341 gaacgttgga agtaggcatc ttgtaaaaaa ggctcggaaa tcagaatact tccttgggct
    47401 ggaaggacat cgttatgtgt tattttaaat atatttttat aagatgccat gatcgtgaat
    47461 gttaggttgt tactaattca ccgacaatat aaggcgtttt ttaataagaa gcaaatgaaa
    47521 agcccgggat tcaagttaat aaacgtgaat cgatcgggct tattgttaat ttatgcttga
    47581 tgattttcct cgaataatct cagtctttcg tccagcaaat catattggtg atcttttatg
    47641 aaagaggtac aagcccgtag tccttgttgg ttactgcctg tggtacttaa agatatggcg
    47701 cttactccgt aataaaccag ttcttccatc aattgtccgc cggtcattcc cgggtaaccg
    47761 atcgtgaaat agaagccgtc ggctatcggt tggtccagat cgtgatcata aacgattgtg
    47821 aaaccatgat ccgtaaaaat cttctttagt ttctccgcac gacgtccgta ttccttcact
    47881 tgcgagacaa agtcgaacgt accgtccgcg gctgccttga acatggcggc taaggcgaat
    47941 tgggccgagt ggctggttcc ggaagatagg gcgtataaga cacggtggat atataccgta
    48001 ccgaacgtac cgcctccata acgctgggtc aatcccggat aggagcgatg gtaaagttta
    48061 ttggagatcg ctgtcacgcc gatacgctgt ccggcatagc tgaacgcttt ggaaccggat
    48121 atctgcatga tataattatc ggtataacgg gctacgctcg cttggtaagg aggctcgaaa
    48181 ggacatccga ggtccttgcg gaaatccatg gcgaaatagg cgaggtcttc tatgacaatc
    48241 acgtcgtatt tgttggccat ctcgccgatg atcttcaact cctcgtcggt gaggcagaac
    48301 caagccggat tgttcgggtt agaatagatc atcgcggcaa tattgccttt ggaaagatgc
    48361 gcttccaagg cctcacgcaa tcgctcgcca cggtattcgt atacgtcgaa cgactcatat
    48421 ttatagccca taacggctat ttgctgtttc tgcacgggga atccggggtc gataaacaag
    48481 atggtgtctt ttcccggcgt acattgtccg gccgtaagga aagaggcgta tgtgccctgc
    48541 atggaaccgg ttacgggtac gcaacactct gggtctatat ctatatttat aaacgccttg
    48601 ataaagcggg aagcttgctt tttcacttcg ggagttccgt tgatgttcgg gtagatagac
    48661 gctataccgt tacgaagggc ttcgatctca gcgtctacgc ctacttgagc ggctttcaag
    48721 cccggtacgc ccatttccat atggatgaac tcggttcccg tttcttgttc caattgcgtg
    48781 gatatggcaa ctacctcccg gatagtcgct ttcccaaaat cgggaagtcc aaagccatcg
    48841 ataatccgtc tggctgtctg atagtctaca ggagtatttt tcatgctagt gttaattata
    48901 tatggggaca aaagtatgaa atttatcgat ttgttctaat tttttcatcc taaactattg
    48961 ctaattcaaa aaatccacct atctttgcac cgcaattcaa cggaatagcg ataaagaata
    49021 acattttggt ctggtagttc agctggttag aatacatgcc tgtcacgcat ggggtcgcgg
    49081 gttcgagtcc cgtccagacc gctttttatt tctccttcct ctttttaaat tttcctttaa
    49141 tacatatttt aatacgatat catccggttc tatggatttt gcctgatggc atgaggttgt
    49201 tatatttgga atgtttatct ttgagaccaa taaaacagat agccttatgg agaatctaat
    49261 aaagatcgat accgtcgatc aatacaacaa gatgtttggc ttggagacgt tgcacccatt
    49321 ggtgagcgtg gtagatttat ccaagtccga gacatggcct actaatttcc gggttaatta
    49381 tggtatatac ggacttttcc tgaaagatac gaaatgcggg gatattcggt atgggaggca
    49441 atattatgat tatcaagaag gaaccgtagt aggattcgct cccgggcagg tgacgggtat
    49501 tgagcttaag gatgggaccc ggcctttggc gcatgggttg cttttccatc cggacttgat
    49561 ccgtggtacg gctttgggac gggacatcaa gcgttattct ttcttctcct atgaatcaaa
    49621 cgaggcgtta catctctctg aggaagagaa ggggatcttc gtggattgcc tgaggaaaat
    49681 ccagatcgag ttggagcact ccatcgacaa gcatagcaaa cggctgatcg cgatgaatat
    49741 cgagttgctg ctcgattatt gcctgcgttt ttatgaccgt cagtttacga cccgtgcgga
    49801 gacgaataag gatgtgttgg tgaggttcga acgattactg gatgaatacc tgcaaagcga
    49861 tctgttaaga caggaggggc tacctactgt acggtatttc gccgagaaga tttgtttgtc
    49921 cccgaactat ttcggtgatc tgatcaagaa agagacaggg aaaactgccc aagaaaatat
    49981 acaagaccgg attatttcct tagcgaaaga atggatatta gggacaaaca agaccgtcag
    50041 ccaaatcgct tacgacctag gattccaata ctcccagcat ttcagccgca tattcaagaa
    50101 gaccgtgggg tgtaccccga atgaatatcg gaaatcccag atgtcgtaat cggtgttacg
    50161 ggctattgga tgtattttat gaccttggcg ggaacacctc ccacgatggc attgtccggt
    50221 acatctttag taactaccga gccggctccg actatagcgt tctcgccaat ggttacgccg
    50281 gataggatcg ttgcgttcga gcctacccag acattcttct tcagaacgat cggggcaggg
    50341 taggtagtgc tccggtcctc gggggcgaag ccgtggttga gggtggcaaa gaccacgtta
    50401 tgcccgatct ggcaaccgtc gtccagtgtc accccgccat gatcttgaaa atgacagcaa
    50461 gcgttgatga aaacgttctt gcctaccgtg atattcttcc caaaatccgt atagaacggg
    50521 gggaatacac gaaaagacgg atcgaccggc ttattaaaca agcgggataa cagctcacgg
    50581 atttcctcgg gatcgtgata tgagccgttt aactcgaatg tcatgcgtct ggcctcatcg
    50641 ctcatcttgt tcataaactg atggatctcg tctcctttaa gaggctttct tgtctctaca
    50701 tacttcaaga attcgtttag tgtcataatt gctattttaa taagttctac ttcttggttt
    50761 gtttatccct tttcgattgc aacggcaaag atcgatgaaa tccggagaaa cttttgtaga
    50821 tggattacag gtattatgac ctaaattaca ttcactgatt ctccaaagcc ttatatttct
    50881 cgattagttt cttgaccgtg acagcgtctg agacctcttg cttataggta gtcgggttat
    50941 aataggcctc gaggaaactg tctgcaccgg accagactgt ctcgataatt ccttggaaat
    51001 ggcgagacat ttccggattt gaatgctggc gaaaatggat catatcatct acctgttgaa
    51061 gcgctatctg aggtttacgc caagggcatg tagcaacgtc gaagcctttc atggcaaagt
    51121 aaacagcggt ttgctcggca cgctcataat gccagtcgca gataaaaaca tctttcggga
    51181 tcaagtcgat cgcacggtgg gtattgttca tgctggcttc ccaagcgccg atcccggtag
    51241 ttttgccatc gatcaggcgg tctccccata tcatcaatcg tttgccttgt gaggctaagt
    51301 ggttttgtat tttagtgacc tcaccggcat ataactcagc cttgtcatgt ccgccgcaac
    51361 ggacgcaact atcatgtccg atataaaaga cctcgtccat cccggcatgg aataattgag
    51421 tctcgaaaac atccgtcaac tcgtctacta aagcgaatac gattttatgt acttccggat
    51481 ggagcgggca gtaactttta caataaagcc cgtctgagtt gggccaaccc gtatagttct
    51541 tggtatccac gtgtggcgtc tcgtcgaact ccggatactc acgtaataaa gcgtaggtag
    51601 tctcagccca tgattgatgc cccaagagat tgatctgggg agcgatacgt attccgttat
    51661 cccggcaaac ctttacgatc tttttcacat cctctcgtgt gagtggggtc ggatccctca
    51721 gttctggatg ggactcatag gcataattcc agtctacccg tagaatcaac aagttgaaat
    51781 gactgggagc cagttcctct tggacgaact tcaagaatag atccaacttc tgtgcggatg
    51841 gagcggcgat ggccaagcct cgtacgggca tgatactatc taaacggttt gtctctgatt
    51901 gggcggaaac ttgggccgaa cctatagccc atataagcaa gaatagtccg ataatctttt
    51961 tcatatagcg atatgtttta atgtttaaat ttttaatttg atgtacgctt tcgaagatca
    52021 tcacgcatat cgtgacggcc cggaggatgt cgatggctat gttacgttgc gtaaaatcta
    52081 ttggttgatc gctcataata tatttagact aaaggtgaat ttaatacaag acaaatataa
    52141 tcaataagag acatatcatt acatttgtgc cttataaata tgaataataa ttaaaaatga
    52201 tagacatgat aagacgattg atttattggg ttctcctgct ttttgtttgt atgggtgccc
    52261 atgcccaatt ccgggtgaca gcccatcaag agggttggga ccggattcct ccgcaagcgc
    52321 aaaaagacgg cttttggttt caacaatccg ttttagcgaa tatggatgat gatgccgcta
    52381 tggaggaggt catgcttttc gggcgggata atgggcatta ccctactttt gacctgttta
    52441 agttttatta cgtgatcgtg gataattata cgagagagat ccaatatata tcggatgaga
    52501 tctatgtgac agataaatat gcgcttacgg tggaggatcg taataatgac gggatctccg
    52561 agttatatat cgattatttc aaggatggga agtttacggt tgatgagcga ggatataatt
    52621 tgcgaaccac ccgttgctac gaccgtatcg aatggagccc cgagagtgaa aaatttaacc
    52681 cccaacaacc atgagaaagt atatctattt tatagcgctt atctgttgcg ccttatcagc
    52741 ctcaacctct tacgcccaga aaaaggtgat aaaaacgatg atgatcgctg ggcaagatgg
    52801 cagtcattat tggcgaggtg cttgcgaggc catgaagcag atcttagaga acagtggaat
    52861 gtttaaggtg gatttcgtct ttaccccgga tttcggagga gatataaata cctttaagcc
    52921 cgatttcgct aaatataact tggttgttgt taattacgga ggtgaagtct ggcccgagcc
    52981 tgtccaaaaa gctttcgaga actatgtagc ggatggtggt ggggtcgtga ttatccattc
    53041 ctccgtggta cctatggccg gttggaaagc gtacaacgag ataatcggca tgggagcttg
    53101 ggaggggcga aacgagaaag acggtcctta cctgtattgg aaagagggca aatatgtata
    53161 cgattataca cccggttatg cgggttatca tggcttgcag catgagacga tcctagagca
    53221 tcgtgcgccg gagcacccta ttttgaaagg tctgcctata agatggaaac attttaagga
    53281 cgagatttat acccgcttgc gtggtccggt acggaatgtg gagatattgg ctaccgctta
    53341 tgagcgtgga cgccatgaac cgttgatgtg gacggtgaag tgggggaagg ggcgtgtctt
    53401 tgtcgatctg ttggggcatt gcggcaatga cccgaatatg atttactcga tggagtgtac
    53461 gggttttcag gtaaccttac taagaggggc tgaatgggcg gccaccgggg aagtgacgca
    53521 agaggcccct cgggatttcc cattggaaga tacctgtacg ctccgtccgg aattcaaggc
    53581 tcctttccat gcgacgaatt aaatgcctta ataagatggt gtctttcgac agaataatca
    53641 aattgacaaa ttgtaaagtt aagtcccgga gaatcgattt ttccgggaca aagtacggct
    53701 cgctcctaaa tacgcaagaa aaaatcagta atcgtttgtt aaatagatag atgtcaaaaa
    53761 acagcctttc attctagcga aattagttca tcgtaattca tatcttatgg gttgtttggg
    53821 ctatctcata gggttacgct ggggaaatga tagggttatg atgcctattc atgacagttc
    53881 ataaccctat tcatgactgc tttcgatgcc caacgtgact attggcgttg cctaacacga
    53941 ctagttgcgt aggctttcat gacctatcgt gtataaaaag cggccttttt gagtaaaaag
    54001 cgccatatat agctatcctc tttcctctac ttggtaacct ctctcaaaag gtagtgttac
    54061 aagatacgct ttatatctat taaaaagaca ggattagatc gtatctttgt cattcgttca
    54121 ttaaagtcat tggttatgtc aaatcaagaa tatatcaaga tcgagggagc ttatgagaat
    54181 aacttgaaac atatctctct ggatattccg aagaagcaaa tcactatatt caccggggtc
    54241 tcgggttccg ggaaatcgtc gttggtattg gataccattg ccgccagttc acgtcgggag
    54301 ttgaatgaga cgttccccag tttcgtgcag caatacctgc ccaaatatgg ccgtccgcat
    54361 gtagaccgga tcgggaatct gccggtcgct atcgtgatag accagcggaa gcccgctccc
    54421 aacgcccgtt ctacggtggg gacttatacg gatatctatt cgttgctccg tctgttgttc
    54481 tcacgggtgg gcaaaccctt tgtcggatat tcggatacat tctcctttaa tcatccgcaa
    54541 ggccgttgta cccgttgtga cggattgggg gagattcgtg agctggacgt gcataagctg
    54601 gttgattttg ataaatgcct gaacgatgag gacgtgatcc attacgtcac cttccagccc
    54661 ggccaatggc gatggatacg ttatgcttgc agcggccttt tcgatctgga taagaagatc
    54721 cgggattata cgccggagga gttgcgctta ttcctttatt ccccgcaaat ccgtttgaag
    54781 aatcctcctg ccgactggcc gaagacggcg aaatatgagg gcttggtaac ccgtatgtat
    54841 cgcagcatca tcaattccga ggaagggaag atccatcaaa aggtcttgga accgatggtt
    54901 acgatgggaa tctgcccgga ttgcggtggg acccgcttga acgataaggt actttcttgc
    54961 cggatcaacg ggagaaatat agccgaagta actcatatgg cgatccccga gataatcgct
    55021 tggcttcggg agattgatga cccgttggcg aaagacatga agcaggcgat cggaggccgg
    55081 ttatccgcct tattggagat cggtttgggg tatttgacgc tggatcgctc catggaaacc
    55141 ctttccggcg gggaggcgca acgctgtaag atcgctaaat atatcaactc atctctttcc
    55201 gatatgcttt atgtgttgga tgagccgagc gtgggcttgc atagccacga tatccattta
    55261 ttgaaagcct cggtccgaaa gttgcgggat catgggaata cggtcttgct ggtggaacat
    55321 cataaggaaa tgatacagat cgccgatcat atcgtggata tggggccggg ttcgggtatg
    55381 gagggcggcc gtatcttgta cgagggagat tatgcgggct tactccgtag cgataccttg
    55441 accggccgta tgctaggaga aaatacccct ctgaaggaaa gcctccggat cccgtccggt
    55501 tggtttacgg taaagcatgc ccgtcttcat aacttgaagg acgtgacggt agatcttcct
    55561 atgggagtac tggcggtgat cgccggtgta gccggttcag ggaaaagctc gttgatggaa
    55621 tgcttccgcc gggatttccc cgaggaggtg atttatatca gccaaaagaa tatcgggatc
    55681 agcttgcgtt ccactccggc cacttatctg ggagttgcgg atgatattcg taaacttttc
    55741 gctaaggaaa gtaaggctgg gcttagtatg ttcacgttta acggaaaagg cggttgcccg
    55801 gtttgtgggg gaaaaggcgt gatcgtgtct gatatggctt ttatggattc gatcgagacc
    55861 gtttgtgagg cttgtggagg attgcgttat tccccggaag ccttgcggta tacagtggat
    55921 ggtcttacga tcgccgaggt gatggacttg acagtccgca aggcttccct tcgttttgcg
    55981 ggaacggtga tagcggagaa actccgtccg cttatgctgg ttggtctggg gtatttgcat
    56041 ttgaaccaag ccttatccac attatcggga ggtgagttgc aacgggtgaa actggcgtct
    56101 tatctaggaa cccaaagcaa ggtctttgtc ttggatgagc cgacggatgg cttgcacgtg
    56161 aaagatgtca ggcatattat ctccttattc gattctatgg tagatcaagg caatagtgtc
    56221 tttttgatcg aacataatct ggatgtcttg aaagcggcgg actatgtgat cgagataggt
    56281 cctggaggcg gactaatggg gggtgagatc ttgtttagtg gtactcccaa ggagttacta
    56341 tcctgcgagc gttccgttac gaaagactat cttgtttgat gattatgaat attataggga
    56401 aagagacgca gcacgctgcg tctctatgtg aatatacgtc aaaagtgagg tcgcttactc
    56461 atcatacgag atattcccta attccttaat cttcgaatct ccgacttgat gcgtgaataa
    56521 ctcaatcaat tgagcgggcg ttaatgtcat ctgaggcgag aactcggagg aatccatata
    56581 acttaataag ctatggtata attggcggac ttccgggtat tcttgttggg tttccaagtc
    56641 tgtcatacag attaataact tgcccgggcc gacattgaat tcttggatca tccctaattt
    56701 atgattacgc tccacgttat cgatcacctg tacgattggc ctgtaattat ccggaagctg
    56761 gtccagtatc aacggatggc tattctttat catcgtgaac cattgccagt ttgtatggaa
    56821 atccgtcggg aaatgagcga aaaccggatg agagggattc attaataatc cgagggtacc
    56881 cggagagacc ggtttcttta cccattcgca gatggactta aacatccggt aattccagta
    56941 atctgtctgg aataatcctt ctaccgtcac gttcttgtaa gtcttggcat ccgggaacca
    57001 caatactttc gccccgttcg ccaataagtt ctcggcctgt ttatcccatt tcttaataac
    57061 attgatatcc gtagggattt gcacgttatt atgttccgga taaatccata acggataatg
    57121 attgtgataa tccgtgccct cgatcgccag ccgtaaagta taggtctcag cctcttgaat
    57181 ggcaggtaaa gcgatattta atgggcctac ctcggccaac gtaccttgat tgatttgcag
    57241 cggtatgttg ttttgggcga ttacttgatc ttgactattc gtcaaggtcc aagttagatg
    57301 tttccctttt aaagtggtag gtgtatagtt cgctaccttg atggagcctt tgagcgcctc
    57361 attcccagag taacagaatt taggtaggag agccagtaat acgacatcat cgcaagactc
    57421 tttccattcc ttggcggtta tcaagccctt attatccata aaagcgtcca agataccgac
    57481 taacgccgtg ccctgtcccg gataatcctg taaatccaat aattggaagc cggccattcc
    57541 cggagtacgg aacgccattt ccatctcggc ccggtaaagt tgcgccatcc atttaccgga
    57601 agccttgaag aaatcatccg cttgtccggc cataccggac tcgcccagtc gtttgcggaa
    57661 tatctccaga ttccaaggtt ttagtgcccc ggtatatttc ttgatttcct cataattcgg
    57721 ataacattgg aattgcccgg tctcatgtcc gatgataggc aatgaacatt gttcgatagc
    57781 ggattcgaaa ttcatgaccg agtttggata ggtatggttg atataaccgc catcctccgc
    57841 atctgcgaaa gagaaggaac cccgggtatg gttgctgaat acgttagcgc cggggactcg
    57901 acaggtcgtg aagtaatcgt cacccgccgc agggccgttg aagcctagat agtcattcga
    57961 tccagatgcg tataaatgcc gtccgtcctc actacggaaa cgggcgatca tgtctaccat
    58021 cgcttcttga tccccggaaa gctcgttgcc gatcgccatc atgacgaaag aggcgtgatt
    58081 cccgtaagcc tcctgtattt gtaatccttc tttggtgagg aaatggatca aagtggtatc
    58141 gcccttttcc atctttcccc agaaaggtag ttccggttgg aggtaaaaac cttcgatatc
    58201 ggccgcctcg aaacaagctt taggaggaca ccatgaatgg aaacggcaat gattgatacc
    58261 gtattccttg gcgatgcgga aatagcgtct ccatgctgcg gtatccatcg gtacatggcc
    58321 tgtaagcgga aatacgcaag catcgtgttt tccacgaagg aaggtggtca atccgttgat
    58381 gttgaattgt gttccttctg ctttgaaatc tcttaatccg aaagtagtac tttggctatc
    58441 ttggatattc tctccttgga tgttcgcggt caagcgatac agggtagggg agaactcgct
    58501 ccattccaag gcgtcatcac ccatcggtat ttggaatatg atctcgtctt gttgaactac
    58561 gatattctta ttgaatttga tatggtgctc taagcctgtg ttgaaagcct ccatctctat
    58621 ttgaacggcg gctacgatca tttgctcgaa tggatttgaa agctttattt ttacgtccac
    58681 cgttttttga tccgcatgtg gatatacttg tatccggcgg atatggaatt gtggacgggc
    58741 ttccaatttc aggtctccga taataccgtt ccagtttgtc tgcgtggatt ccgtataagc
    58801 gtgtgaattg tccaataatt ggggcggaac gctcaaaccg ttatcgacta gaatagtcaa
    58861 gtgatgcttc ccagcccgga gatatgcgga cagatcgtat tcttgagggg tggaaatatg
    58921 gtcggatgaa ccgacatata tgctatctac ccatatttgg gtcggttttg ttcgctccaa
    58981 gattaaccaa atgctcttgc cttcccaatt ctctggaatc gtgatctctt tctgatacca
    59041 agccttacct tgatagcgga agggcctaga caaatgagtt gtctcctcct tatcattgtt
    59101 agggtatcct ttttggttgg tgtccgtggt acccggtaat tgaacttgct cggtgacatc
    59161 tgttgaatcc aatcgtaatt cccagcaacc ggcaagcgat aattcctctc tactctcttt
    59221 gggagtttgg catgcgaata gcatgagcat aagtggaata ctccaaaatc tcttcatggt
    59281 aatgttttta ctctaaatat ggtttactta attaatagtg tacaaaggta gtatttttgg
    59341 cctttttatt aaggagaaga tatgaaaaaa gaagaagatt ttgttatggg cctgtccatc
    59401 tacatggctt gtctgcg
//
LOCUS       DBMDTB010000010        58855 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_222_length_58855_cov_10.926286, whole genome shotgun sequence.
ACCESSION   DBMDTB010000010 DBMDTB010000000
VERSION     DBMDTB010000010.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 58855)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 58855)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58855
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_222_length_58855_cov_10.926286"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(14..87)
                     /locus_tag="ACZPB4_02975"
     tRNA            complement(14..87)
                     /locus_tag="ACZPB4_02975"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(51..53),aa:Arg,seq:acg)
     gene            complement(116..189)
                     /locus_tag="ACZPB4_02980"
     tRNA            complement(116..189)
                     /locus_tag="ACZPB4_02980"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(153..155),aa:Arg,seq:acg)
     gene            complement(217..293)
                     /locus_tag="ACZPB4_02985"
     tRNA            complement(217..293)
                     /locus_tag="ACZPB4_02985"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(257..259),aa:Arg,seq:acg)
     gene            complement(370..2688)
                     /locus_tag="ACZPB4_02990"
     CDS             complement(370..2688)
                     /locus_tag="ACZPB4_02990"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HIR1097221.1"
                     /translation="MRKITVIIALFLAAIQIVSAQKVGLVLSGGGAKGAAHIGVIKAL
                     EENNIPIDYITGTSIGAIIGSLYAMGYSPEEMLELMLSKEFAYWQTGTVEEQYTYYFK
                     EPYPTPEFAHFSIDMSDSLQIKASFLPQSLINPIQMNQAFMALFSQATAKAGWNFDNL
                     FVPFRCVASDIYTKKPIIFKNGDLGDAVRASMTFPFFFQPIWKDSIPLFDGGIYDNFP
                     VGPMKDAFHPDFIFGSTVSGGNKKPSENPYNQIETMIMQKTDYEVPEEDGMMIKFSFP
                     TVSLLDFQKGKELMDIGYKRTLSMIDSIKQRVPREVPLNEVTERRKAYKENLPPLIFR
                     NIYVTGVSEAQRKYIEAQLHRDINNEFSMEEFKRAYFKMLTYSKIREIMPHAVYNRKE
                     KKFDLYLDVKMKEEITVGFGGNVSSHQANQLYLGLGYQYLGRFAADVNSNFQVGNSFS
                     GVMLSGRMYLQTQIPTYLNWQGVFSDKKYTESQSLFYEDIVPAMIKQKELYMKLKLGF
                     PFLNHAKAEIGFAYGRLNDFYLQSTTIPFPNASFDHSWYDLFSGSLSIEQNSLNTKQY
                     PISGKQQFLIAQYVTGTEKYTPSPTSATTEAPIGRKVHSWLQLKGRWNQYQTLSNRFN
                     LGYLAEMVISSKNLMNNYTASVLQAPAFTPTPHSEIVFNEAFRANQYVAFGLSPILKL
                     SKLLHFRLDMYGFAPLYEIQKTVPENNPYVGIPHYGKFLHSFNYMGEAAVVLQLPFLC
                     ISLYANGYSYPKENFNFGLNIGYLIFNPKMLD"
     gene            2801..3124
                     /locus_tag="ACZPB4_02995"
     CDS             2801..3124
                     /locus_tag="ACZPB4_02995"
                     /EC_number="1.8.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HIR1097222.1"
                     /translation="MKEKELNREERNKTVMETGALVMAEFYADWCPHCQKMMPIVKEF
                     KELEKGKLEVVQINIEEESALADLYTVESIPTFILLRKGEALWRQSGEMSLDRLRKVV
                     EDVVG"
     gene            complement(3182..5236)
                     /gene="htpG"
                     /locus_tag="ACZPB4_03000"
     CDS             complement(3182..5236)
                     /gene="htpG"
                     /locus_tag="ACZPB4_03000"
                     /inference="COORDINATES: protein motif:HMM:NF003555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone HtpG"
                     /protein_id="HIR1097223.1"
                     /translation="MSSKQGNIGVTSENIFPIIKKFLYSDHEIFLRELVSNAVDATQK
                     LKTLSSVGEFKGELGDLTVQVKFDDKTITISDRGIGMTAEEIDKYINQIAFSGAEEFV
                     EKYKNDAASIIGHFGLGFYSSFMVSKKVEIVTKSYKEGAVPMKWSCDGTPEYSLEETT
                     KEDRGTDIILYIDDENKDFLNKDKINGLLTKYCRFLPVPIAFGKKQEWKDGKYVDTDE
                     DNVINDTKPAWVRKPADMTDEDYKKFYRDLYPMTDEPLFWIHLNVDYPFNLTGILYFP
                     RIKSNIDLHRNKIQLYCNQVFVTDSVEGIVPEFLTLLHGVLDSPDIPLNVSRSYLQSD
                     QNVKKISNHITKKVADRLEEIFKNDRPQFEEKWDSLKLFIQYGMLTDEKFYDRAVKFA
                     LFKDVEGKYFTFEEYKNLIKDNQTDKEGNLIYLYTTNKDEQYSYIQAAKDKGYSVLEM
                     DGQLDVHLIGQLEQKFEKSRFVRVDSDTIDNLIRKEDSNKVTLSEEQKTAMQEVFKSQ
                     MPKLNKTEFYVTFEALGENANPVMLTQSEYMRRMREMSAMQPGMSFYGEMPDSFNFVL
                     NTDHPLIKKVLTEEEQACDEKLKPILSDIKGWEARQADLREAQSKKKEDEITAQEKED
                     MTNTDHKLDELREQRNQVLAEYAGTNKTVSQLIDLALLGNGMLKGEALSQFIKRSVEL
                     IG"
     gene            complement(5407..7011)
                     /locus_tag="ACZPB4_03005"
     CDS             complement(5407..7011)
                     /locus_tag="ACZPB4_03005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016267273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HIR1097224.1"
                     /translation="MITMKELGAPIRQWVPDWLGLICIFIVILPVTMLNGSYTGSMLE
                     VSNTLGTNTEDITMGYYAAAAGMAVSYPIIPKILEAFSIKFLLLADLVAQFFLSWICA
                     RSQNADILIVCSFAIGFLKGFLMLWFIRYAQKIFSPKNIRSQFYSYFYPFVFGGGQAS
                     MLVTAQLAYHYDWKYMYYFMMLMILLAIVMVIISFRHNRPIKSIPLADLHIREMFIIS
                     TGLLMLMYVINYGKVLDWMASPKICLYIMIAPILIALFIWYQYHSERPYVNLAPLYQP
                     KAIIGYFYMMLVMFFSTSTTLLTSYLTSILKVDSTHTYSLYTYLLPGYVLGAFICFWW
                     FRWQRWRFRFLIAGGMSCFVLFFGSLYFGISPDSRYEMLYFPIFLRGLGMMILIIAFA
                     LFAVEDLNPKYLLSNAFFLIIFRSVLSPIMATSFYSNILYRLEQKYMYSLSETVTLAD
                     PLAASRYNQALGNALTQGHPYDEAAQMATNTLYNTLQQQSLLLALKEILGYLLVISLF
                     IAIVSRFIPFHKTIRVTFAKTGDDMV"
     gene            complement(7008..8078)
                     /locus_tag="ACZPB4_03010"
     CDS             complement(7008..8078)
                     /locus_tag="ACZPB4_03010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HIR1097225.1"
                     /translation="MANELKEKHQRLKKVRTRNIVLNSICILLAGSGIWWTANYFWRY
                     INYEVTNDAFVDQYIAPLNIRASGYIKEVRFKEHQYVHQGDTLLILDDREYRIKVKEA
                     EAALIDAQGSQDVLRSGIETSHTNIAVQDANIAEAKAKLWQLEQDYHRFERLLKEESV
                     PEQQYEQSKAAFEAAQARYQALVEQKKAAFSQFTETSKKTTGAEAAILRKEADLDLAR
                     LNLSYTVITAPYDGHVGRRTLEPGQYVQAGQTISYLVRDKDKWITANYKETQIPHIYI
                     GQKVRIKVDALPGKIFNGEVTAISDATGSKYSLVPTDNSAGNFVKVQQRIPVRIDLEN
                     LSQEDTQYLRAGMMVETEALRK"
     gene            complement(8094..9413)
                     /locus_tag="ACZPB4_03015"
     CDS             complement(8094..9413)
                     /locus_tag="ACZPB4_03015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HIR1097226.1"
                     /translation="MSLRIYKKHVLSLFCMTVATFPAIAQTDSLFLTIDQLFERGVRH
                     SLQIQADVLKESIAQERTHTARSAQLPDLQIGLKGGYVGQPILFEQGLAHPTRPEAPD
                     WSQNYAIDLTQPIYQGGKIRYSIRKADLEKEVASLQTLTDQSEIKLGLLNQYIGLFSL
                     FKQREVLSRNIEESERRLQDIRRMKKEGLITNNDVLRSEMQLTNDRLSLQETDNSLIL
                     VSQQLDILIGLDENLLLKPDTTLLDQIVSLETYEDYVAQAYSNDPAIRLLRKQTELAQ
                     NDIRLTKASSLPSLSLYASNTLARPVSRTLADMYNNNWNIGLSLSYPLSSLYKNNHKI
                     KESKWMVSLHKNEEEQKKQKIRIEVRTAFLRHKEALQEVEALKLSVRQAQENYRIMQN
                     RYLNQLAILTDLLDANSVLLNAELQLTNARTHVIYTYYQLQKACGRL"
     gene            complement(9394..9834)
                     /locus_tag="ACZPB4_03020"
     CDS             complement(9394..9834)
                     /locus_tag="ACZPB4_03020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HIR1097227.1"
                     /translation="MVEGKEFRELMLQVVRTRMAFRRSMQRTLKKNNAGITFEMLQIL
                     SCLWHEQGITQQVLAERTAKDKACLTNLMNNLEKKGYVHRKEDPEDRRNKLVFLTPEG
                     EEFKKQIRPILDQVYVHAEHIIGIENVETMLSELKAVHNVLENI"
     gene            complement(10159..10662)
                     /locus_tag="ACZPB4_03025"
     CDS             complement(10159..10662)
                     /locus_tag="ACZPB4_03025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HIR1097228.1"
                     /translation="MKTGLFYGTGTEKTTFVANKIRKAFGEDQIDIIPVESAWKRDFE
                     AYDHIIAGTSTWFDGELPTYWDEIIPELVTLDLKNKKVAIFGLGDQTNYPDNFADGVG
                     ILADAFTSCGATLVGETSSDDYFFNASKALKNGKLLGLVLDLENQPDQTDKRIERWVK
                     QLKEAFG"
     gene            complement(10696..12729)
                     /locus_tag="ACZPB4_03030"
     CDS             complement(10696..12729)
                     /locus_tag="ACZPB4_03030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045240 - alpha-ketoacid dehydrogenase
                     complex [Evidence IEA];
                     GO_function: GO:0016903 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit alpha/beta"
                     /protein_id="HIR1097229.1"
                     /translation="MKKYDIKTTDKETLRKWFYLMTLGRAIDEKAPSYLLQSLGWSYH
                     APYAGHDGIQLAMGQVFDKDTDFLFPYYRDMLTVLSAGMTAEEIILNGISKATDLTSG
                     GRHMSNHFSKMEWHIENVSSATATHDLHAAGVARAMVYYGQKGVAITSHGESAASEGY
                     VYEAINGASNERLPVIFVFQDNGYGISVPKKDQTANRKVADNFSGFKNLRIIHCNGKD
                     VFDSMNAMTEAKEYAIANRTPVIVQANCVRIGSHSNSDKHTLYRDENELTYVKSADPL
                     YKFHRMLIRYGRFTEEELKEIADLAAKDLKAANRKAMAAPDPDPSTVKDYVLPEPYQP
                     QKYKEGVQNEEGEKETLVMAINKTLKAEFRHNPDTFIWGQDVANKEKGGVFNITKGMQ
                     QEFGIERVFNAPIAEDYIVGTANGMCRFDPKIHVVIEGAEFADYFWPAVEQYVECTHE
                     YWRSNGQFTPNITLRLASGGYIGGGLYHSQTIEGALTSLPGARIVYPSFADDAAGLLR
                     TSMRSKGFTLYLEPKALYNAVEASTFVPEDFEVPFGKARIRRPGKDLTIITYGNTTHL
                     CLNVAELLYKEKGWELEVIDLRTLIPLDKEAIFNSVKKTSKVLIVHEDKVFSGFGAEI
                     AGIIGSELFQYLDAPIQRVGSLFTPVGFHPVLERAILPNEETIYHAAKELLLY"
     gene            complement(12752..14086)
                     /locus_tag="ACZPB4_03035"
     CDS             complement(12752..14086)
                     /locus_tag="ACZPB4_03035"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045240 - alpha-ketoacid dehydrogenase
                     complex [Evidence IEA];
                     GO_function: GO:0016407 - acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase family
                     protein"
                     /protein_id="HIR1097230.1"
                     /translation="MATFEIKMPKLGESITEGTIISWSVKVGDTVEEDDVLFEVSTAK
                     VSAEIPSPVEGKVKQLLFNEGDTVAVGTVVAILEIEGEGEDNGAQPETSEATQPKEQV
                     PAPASEELSKNSQEEDRWYSPVVLQLAKAAGVSQDELDHIPGTGYLGRLSKKDIQTYI
                     DHKNKGTEMPKPKQAPVSSMQQTATSTPIITVAPPTAPSMPMTAATPSAPLAQGDEVR
                     EMDRVRKIIADHMVLSKKVSPHVTSVIEVDVTRLVNWRKKVKDQFFKQEGINLTYMPA
                     ITEATAKALKAYPLVNSSVDGYNIILKKPINIGIAVSLNDGNLIVPVIHDADKLNLSG
                     LASQIDTLAAKARENKLAPDSIQGGTFTITNFGTFKSLFGTPIINQPQVAILAVGYIE
                     KKPAVVETPEGDTIAIRHKMYLSLSYDHRIVDGALAGAFLRSIADELENWNA"
     gene            complement(14190..14933)
                     /locus_tag="ACZPB4_03040"
     CDS             complement(14190..14933)
                     /locus_tag="ACZPB4_03040"
                     /EC_number="2.3.1.-"
                     /EC_number="6.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009107 - lipoate biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HIR1097231.1"
                     /translation="MLCIHNTQTDPYFNLAAEEYLLKNFKENIFMLWQNEPSIVIGKH
                     QDVWAEVNLKFVQDQQIKIARRFSGGGAVYHDPGNLNLTFIETGQIMQTDKYTIQIMN
                     FLKTLGVHVEMDERKGLTIGGFKISGSAQSIHKNRYMHHATLLFSTDLDRLVTSLKST
                     SRQTPEKTGGKRSTFVKSVRSPVTNISAHLPASISIQHFKKALLYYFTINNPGIQDYS
                     FTQADLEAIYRLKEQKYATASWNFNTYTL"
     gene            complement(14962..16311)
                     /gene="lpdA"
                     /locus_tag="ACZPB4_03045"
     CDS             complement(14962..16311)
                     /gene="lpdA"
                     /locus_tag="ACZPB4_03045"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010183358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     (NADH) activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HIR1097232.1"
                     /translation="MEYDIAIIGGGPAGYTAAERASENGLKTILFEKNAIGGVCLNEG
                     CIPTKTLLYSAKILDSIKSASKYGIVAMKDPSFDLAKIIDRKNKTVRKLTLGVKARLT
                     GNGVTIVEGEARITGEEFGNIRIHCDGKEYLVKNVLVCTGSETVIPPIKGLSEVKYWT
                     SREALDLNDLPKSLAIIGGGVIGMEFASFFNSMGVKVKVIEMLPEILGNMDKETSAML
                     RSEYKKKGVEFFLNTKVTEVSAEKVFVEKNGKADTIEADKILVSVGRRPITKSLGLEN
                     LAIEIQGAGVKVNEHMLTSHPHVYAAGDITGFSLLAHTAYREAEVAIHHILGIPDEMS
                     YKAIPAVVYTNPELASVGKTEEELVANGESFRVQKIPMTYSGRFVAENENGNGLCKLI
                     TDDEDRIIGCHLLGNPASEIIVTAGIAVENGYTVDEFKKNIFPHPTVSEILHESLYI"
     gene            complement(16327..16929)
                     /locus_tag="ACZPB4_03050"
     CDS             complement(16327..16929)
                     /locus_tag="ACZPB4_03050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005779392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HIR1097233.1"
                     /translation="MARSFKEAIQHRRTHYGIGNNSPISDNEIHEIIKTAVTHVPSAF
                     NSQSTRIVLLLGESHKKLWEIVKDTLRKIVPAEAYKATEAKIDNSFEAGYGTVLFFED
                     TAVVEGLQKQFPSYKDNFPVWSQQTSAMHQLAIWTMLEDAGFGASLQHYNPLIDEAVA
                     KQWHINPNWKLIAEMPFGTSTQEPGEKQFAPLEERILVFK"
     gene            17164..17403
                     /gene="rpmB"
                     /locus_tag="ACZPB4_03055"
     CDS             17164..17403
                     /gene="rpmB"
                     /locus_tag="ACZPB4_03055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HIR1097234.1"
                     /translation="MSKICQITGKRAMVGNNVSHSKRRTKRKFNVNLFTKKFYWVEQD
                     CWVSLNISAAGLRTINKLGLDAAIKMAAEKGYLNA"
     gene            17423..17611
                     /gene="rpmG"
                     /locus_tag="ACZPB4_03060"
     CDS             17423..17611
                     /gene="rpmG"
                     /locus_tag="ACZPB4_03060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012573149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HIR1097235.1"
                     /translation="MAKKAKGNRVQVILECTEHKESGMPGMSRYITTKNRKNTTQRLE
                     LMKYNPVLKKMTLHKEIK"
     gene            17628..17780
                     /locus_tag="ACZPB4_03065"
     CDS             17628..17780
                     /locus_tag="ACZPB4_03065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005638125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4295 domain-containing protein"
                     /protein_id="HIR1097236.1"
                     /translation="MAKKAVATFKKGDGRTYSKVIKMVKSPKTGAYIFQEEMIPNEAV
                     KDYFAK"
     gene            18000..19124
                     /gene="dnaN"
                     /locus_tag="ACZPB4_03070"
     CDS             18000..19124
                     /gene="dnaN"
                     /locus_tag="ACZPB4_03070"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009000039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HIR1097237.1"
                     /translation="MRFDVSSTALLSRLQSISKVIASKNSLPILDSFLFNLEGNTLTV
                     TASDAETRLVTSVDVMNAQGAGLFAVSAKILLDPLKELPEQPLTFDINDENLEIFIHF
                     QNGKYNFIGQKGDTYPQQKPLNDNAISISMDAQMLLNGISRSLFATADDELRPVMNGV
                     YFDIHTDDLTFVASDGHKLVRLRNLAVKSPERASFILPKKPANLLKNLLAKESEQVLI
                     KFDDNNAYITCTNFEMVCRLIEGRYPNYNSVIPQENPFKVTIDRISFLNALKRVSVFS
                     NPASSLVKLHLKDSLITVSAQDIDFSTSAEERIVCQFDGTELSIGFKATYLIEILGNI
                     SSEEVVLELADPSRAGLIVPSENDEDEDLLMLLMPMMLND"
     gene            19135..19905
                     /locus_tag="ACZPB4_03075"
     CDS             19135..19905
                     /locus_tag="ACZPB4_03075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005638110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HIR1097238.1"
                     /translation="MQLNLRNPLVFFDLETTGINIVKDRIVEISYVKVFPNGKEETKT
                     RRINPGMPIPPESTAIHGITDEDVKDCPTFKEIAKSLATQIEGCDLAGYNSNRFDIPM
                     LAEEFLRAGVDIDLNRRKFIDVQTIFHKMEQRTLSAAYKFYCNKSLENAHTAEADTLA
                     TYEVLKAQLDRYPDLKNDVAFLSQYSCYSNNVDFAGRMVYNDKGEEVINFGKYKGRLV
                     TEILKSDPGYYSWIMNGDFPLNTKKMLTEIRLRDFNSK"
     gene            19910..21061
                     /locus_tag="ACZPB4_03080"
     CDS             19910..21061
                     /locus_tag="ACZPB4_03080"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0018455 - alcohol dehydrogenase [NAD(P)+]
                     activity [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HIR1097239.1"
                     /translation="MNNFEFCNPVKVVFGKGSIARLSALLPEGSKVLVVYGGGSIKKN
                     GIYEQVTAALKDFHTYEFGGIEANPRYETCMKAVELVKGENIDFLLAVGGGSVIDATK
                     FIASATFFEGDPWDILSKGGVIKKALPLGVVLTLAATGSEMNERAVISRESVHEKLNF
                     MSPLVFPKFAILDPQVTYSLPERQVANGVVDSFIHVVEQYLTYPVNAKVQDYFAEGLM
                     KTIVEEGRKVLQNPNDYDIRANLMWAATNALNCWIGQGVPQDWSSHRMGYALTAQFGL
                     DHAQTLAVILPGVMTYMRKEKAAKLIRMGEVIFGITEGSADEKAQKSIEATEDFFHFM
                     GLKTRLSDYGIKESDLDALVEPIDRMGWKLGEYGNINSKVAKEILLLRL"
     gene            21111..22316
                     /gene="coaBC"
                     /locus_tag="ACZPB4_03085"
     CDS             21111..22316
                     /gene="coaBC"
                     /locus_tag="ACZPB4_03085"
                     /EC_number="4.1.1.36"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004632 - phosphopantothenate--cysteine
                     ligase activity [Evidence IEA];
                     GO_function: GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0015941 - pantothenate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphopantothenoylcysteine
                     decarboxylase/phosphopantothenate--cysteine ligase CoaBC"
                     /protein_id="HIR1097240.1"
                     /translation="MILKDKHIILGITGSIAAYKAAYIIRGLVKKGAEVQVVITPAGK
                     EFITPLTLSTLSSHPVISEFFSNRDGTWNSHVDLGLWADAMLIAPATASTIGKMANGI
                     ADNMLITTYLSCKAPVFVAPAMDLDMFAHPSTQQNLERLRSFGNRIIEPAEGELASHL
                     VGKGRMEEPDKIIEVLEDFFSAQKDLEKKKILITAGPTYEKIDPVRFIGNYSSGKMGF
                     ALAEACAERGAEVTLVAGPVSLKTHHPAIKRIDVESAGEMYQAAMTAFPSSDAAILCA
                     AVADYRPENASEQKIKRETEREMTLHLVPNPDIAASLGAIKREGQVMVGFALETNDEA
                     THAEGKLKRKNLDFIVLNSLRDQGAGFRCDTNKITIIDNAGGVTSYPLKTKREVACDI
                     VNKLVTLLK"
     gene            22313..23224
                     /gene="porD"
                     /locus_tag="ACZPB4_03090"
     CDS             22313..23224
                     /gene="porD"
                     /locus_tag="ACZPB4_03090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0160303 - protein secretion by the type IX
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type IX secretion system protein PorD"
                     /protein_id="HIR1097241.1"
                     /translation="MRKVRRLFYLFMLCAAPFCGKAQELNARITVNGDKIATANKQIF
                     TTLQNSLTEFVNNRKWTDATFAVNEKIDCTMTIIVNELDETNFKSEIQIQARRPVYNS
                     SYTTTLLNFRDQQLDFEYTEGEPLDYNSNTLTSNLTATIVFYVYVILGLDFDSFAPKG
                     GTTYIQQAQQIVNMAQSEMSWTGWKAFDSNQNRHAVATALQDNASDAFREMWYTYHRK
                     GLDEMAANPDRGRTTIISALPALQEVKKARPTSVLLQMFADAKLDEIIAIYSKATTQE
                     RQEGYKMLFEIYPAQSTRLEELQKPVR"
     gene            23232..24896
                     /gene="recN"
                     /locus_tag="ACZPB4_03095"
     CDS             23232..24896
                     /gene="recN"
                     /locus_tag="ACZPB4_03095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HIR1097242.1"
                     /translation="MLKSLFIQNFVLIDNLDIRFDKGFSVITGETGAGKSIILGALSL
                     VLGQRADGKSIKKGSDKCVIEAVFDVSKYQLEPFFLSNDLEYDADSCILRRELYASGK
                     SRAFVNDSPVSLTILKELGSRLIDIHSQHQNLLLGDNRFQLKVIDVMAENEILLILYK
                     KEFTRYQALRRELKDLRDKAAQSKQEEDYIRFQLEQLDEANLQPDEQDELEQEQETLS
                     HAEEIKSSLYKVTELLDGEEQGAIQILKEALSTVDSLERYFPKAKEISERIRSAYIDL
                     NDLASETDVLKEDVEFNPERLEWVNERLNILYTLLQKHRVSTVDELIAIRDQYQEQLR
                     AIDSFDEQIGLLESQLDASYKELLQQASVLSEQRKVASTAMASQLVKMIIPLGMPNTR
                     FRVDILPRKEPESDGMDDIRFMFSANKSAELQPVAQTASGGEISRLMLCIKAMIAGFT
                     ALPTIIFDEVDTGVSGDIADKMGDIMQELGTKMQVFAITHLPQIAAKGQAHYFVYKKD
                     TKDRTLTRIKQLEGEERVNEVARMLSGASLTEASLANAKDLLGIKD"
     gene            24972..25604
                     /locus_tag="ACZPB4_03100"
     CDS             24972..25604
                     /locus_tag="ACZPB4_03100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097243.1"
                     /translation="MKRFSLLCVLAILCSLPAYSQFWISFGWNEPHCQNCLWMEQAMH
                     LPARQAAEYHKIIHKYGQKIEKEARRDYRYWDRAARRIYDLRMERDRKIQRLLTPAQF
                     NLYVRFVREHPQRIHDYRGWYANPRYPDRRPSHDCRRYEDNYWNYRWGTIHHDNHWRD
                     DRHDSDRHWDRDNHRHDYRKPAKPDKPKPKKNKKDRDDRKERYYSNGRKV"
     gene            complement(25601..26379)
                     /locus_tag="ACZPB4_03105"
                     /pseudo
     CDS             complement(25601..26379)
                     /locus_tag="ACZPB4_03105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772389.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
     gene            complement(26372..27412)
                     /locus_tag="ACZPB4_03110"
     CDS             complement(26372..27412)
                     /locus_tag="ACZPB4_03110"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1097244.1"
                     /translation="MKEISYGKSACILLFSALGVFSYFLLLYHTELQERIPDIKISLI
                     ALSITIAVFNLFGFSLLVSSHWMATNYPLYYIDKSRMLWHYLLVAILLLLMNCTLFIS
                     LKWITSIGDPFVIRAKGAGLVIAVWFVEMIIFSLLLINYSMRYTLNLYKEKQRLEAES
                     IQAKYTALQSQLNPHFLFNSLNTLIAEIEYDPATAVKFTQHLSEVYRYVLRQQQCQIV
                     SLKEELDFLDSYIFLHQVRLGDCLSLERDLPDNVIDHQLPPLTLQLLAENVVKHNYID
                     DFNPMTIRVYTERNSRYLCVSNTLRPKKVSNASGKGLKNLSERYQLLCKQDIQIRKND
                     HQFTVSIPLIYE"
     gene            complement(27416..28726)
                     /locus_tag="ACZPB4_03115"
     CDS             complement(27416..28726)
                     /locus_tag="ACZPB4_03115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HIR1097245.1"
                     /translation="MDKVYIISGLLSFLSFPLIAQNSDYQAQYREKVLEYNQDLKAAG
                     YNEAMKQEMIKSARADFKPKLSAEGNFNYTGNPLELSIDLPSMNSPLYFQGKDLKYGA
                     TLSLSQPIYTGGGIRANYQKARQEKELASNESDRIKSNTLHDADIYYWNAVAQHELVF
                     VAQAFRTSIQQLVDVVRHRVEVEYIDRNDLLMAEVKLNDADFQLLQTRDNAEIARLAL
                     NSFAGVNPSDTLPIDHSVIALKQFIPLSDEIDNAITSRPEYRIAKNKIELQESSRKIA
                     DAHFLPQFHIGVDGSYSSPGYNFKSDLDPNYAIYAKLSIPLFEWGKRKSTRNASSYAI
                     NMAQQNLSKTQDKIRLEIQTAHYNYKQAIDKVELTESSLSKASESEQMAMERYKEGNV
                     SIVEVINAQLYHQQAQVNYIQSKLNAQMAKTDFERAIYYLREKE"
     gene            complement(28736..31777)
                     /locus_tag="ACZPB4_03120"
     CDS             complement(28736..31777)
                     /locus_tag="ACZPB4_03120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0042908 - xenobiotic transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HIR1097246.1"
                     /translation="MQKFIKYFLKNKAVTWLLLVLILAGGLFSYAKMGKLGDAPFTIK
                     QALVLTPYPGASPSEVQFQVTDVLEEAIQSLGELYYLKTENRAGLSKITVYVKKEIRA
                     DEMQQLWDKLRRKVNDVQGKLPSGAGTSIVNDDFGDVLGVFYGLTGESYTYRELEDQA
                     KLIKDDLLKVKDVAKVEIYGIQTPVIDIRINPTILSNRGITTADIKRAFDGQNKMVDA
                     GSIRNGETRIRIESTGNFYSLDDIRNLTIVSHSGEHFRLGDIARIEESYQTPPQNFMR
                     INNKQAVGIAISTVPTGNVVDMAKAVKKRIQSFSETMPKGFELTSIYDQGYESAVANQ
                     GFILNLIISVVTVVAILLFFIGFKNGLLIGSGLVFSIFATLIVMFANGIALQRMSLAA
                     IIIAMGMLVDNAIVVSDSALVNMQRGMRKRIAIMRACSSTALPLLAATAIAILTFLPI
                     YYSPHITGELLSSLVIVIGVSLMFSWVFALTQTPFFIQEFVRRPRPDELTGELFSGKY
                     YDYFRSSLRLVIKYRYATVGSLSVLLVISAWSFQFIPKVFVPSLDKQYFTLDMWLPEG
                     TAIEETDRYATDMAESIQEYSQTEMVSSYIGRTPPRYYLSNVSFGPQPNYAQLLVKCK
                     TSGEARELHALLQDSIRLKYPEPLINVNKFELSPLTEALIEARFLGPDPAVLDSLTGV
                     AIDIMRRNPKVTDARNEWGNMTYMIRPVYDPVKAGFLGITKANLMESVKSIEEGTVIG
                     IYRDEEKKVPVLLKSEKSGIDDPRSLGDFSVWNGEKSAPLSQVTRQVTSAWEYPQIKT
                     YNRQLSMAAMCGVKNGYTMSEVHGEIREEIEKMNLPQGYSFFWDSQYKDQTEGLQALV
                     KFFPLAFLMLVVILVALFSNFRQPIIILCVLPLSLIGVAIGMLLTGFDFGFFPIAGWL
                     GLLGMIIKNVIVLLDEINTQRRNGISPYDSIIEATISRTRPVLMAATTTILGMVPLLF
                     DVAFGGMAATIIFGLTFATLLTLFVTPTLYALFYRIHSPHK"
     gene            complement(31783..32409)
                     /locus_tag="ACZPB4_03125"
     CDS             complement(31783..32409)
                     /locus_tag="ACZPB4_03125"
                     /inference="COORDINATES: protein motif:HMM:TIGR01730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HIR1097247.1"
                     /translation="MQLRDRRQRLKRHHLSAPYDGYIQNIHIEPFQDVKATEPILTFI
                     ELDRLKIETYIPEEVALHLYDKEKQKLCQIEIHFDTAPERTITPSDLYVSKSTTNNNL
                     SYLLTAIVPNPDMEWLGGMSGILSIDLPKEERSQNLWLPLTAICHRPQKGDYVWVVKG
                     DKVNSVPVKLGEQRNNQIEIVEGITGNDLVVLTRQRFLSENSTVTIQK"
     gene            complement(32307..32822)
                     /locus_tag="ACZPB4_03130"
     CDS             complement(32307..32822)
                     /locus_tag="ACZPB4_03130"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097248.1"
                     /translation="MRRISYILLLGILLSACQKNTKSKGTNLPVEVISPIKKTETGRS
                     REYTFLSRPYNETVLSFRINGPVLNFDLRPGQAFSKGSTILLIDNRDFLIRKQQTEAL
                     YSQTNQEYKRIEALYKKNNISGSNYERAKADFLVAKSNYETAVNALSDTICPPLTTDI
                     SKISISNLSKT"
     gene            33195..33785
                     /locus_tag="ACZPB4_03135"
     CDS             33195..33785
                     /locus_tag="ACZPB4_03135"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004797 - thymidine kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HIR1097249.1"
                     /translation="MTLPSEEHIFQYPGQGRIEVICGSMFSGKTEELIRRLKRAEFAK
                     QRVEIFKPAIDTRYSQDNVVSHDSNSIPSTPVDSSSSILLFTSEIDVVGIDEAQFFDE
                     GLVNVCNQLAANGIRVIVAGLDMDYKGVPFGPMPELCAIADEVTKVHAICVKCGRLAY
                     VSHRIVRNDKRVFLGEQSEYEPLCRECYAKAEGLKN"
     gene            33835..34581
                     /gene="rlmB"
                     /locus_tag="ACZPB4_03140"
     CDS             33835..34581
                     /gene="rlmB"
                     /locus_tag="ACZPB4_03140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HIR1097250.1"
                     /translation="MKENEMVFGIRAVIEAIQADKEVDKILVKRDLQGDLSKELFEVL
                     RGREIPVQRVPAERLDRLTRKNHQGVIAFMSAVTYQSLEDIIPFVYEQGKDPFIVLLD
                     GVTDVRNFGAIARTCECAGVDTIVIPAKGSVSVNADAIKTSAGALHVLPVCKEKSINQ
                     AIRFLQQSGVKVFAASEKAAENYTAVKYEGPVAIVMGAEDTGVSPENLRICDNMVKIP
                     QFGTIGSLNVSVATSILVYEVVRQRMNEQQ"
     gene            34609..34989
                     /locus_tag="ACZPB4_03145"
     CDS             34609..34989
                     /locus_tag="ACZPB4_03145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008149461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HIR1097251.1"
                     /translation="MKKVIATKNAPAAIGPYSQAVQVGNMLFASGQLGIDPATGLFVE
                     GSVKEQTAQAFKNVHAILAEAGYSINDVVKTTVFLADMGDFAVMNEVYASQFEGAFPA
                     RSAVAVKTLPKNGLVEIEVIAVKE"
     gene            complement(35116..36966)
                     /locus_tag="ACZPB4_03150"
     CDS             complement(35116..36966)
                     /locus_tag="ACZPB4_03150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YgiQ family radical SAM protein"
                     /protein_id="HIR1097252.1"
                     /translation="MKTFKLDNWLPTTKKEVEARGWGYLDVILFSGDAYVDHPSFGAA
                     VIGRVLEAEGLRVAIVPQPDWRGDYRDFKKLGVPRLFFGVSAGAMDSMINHYTANKRL
                     RSDDAYTPDQRPGMRPDYPSIVYTKILKELYPDVPVVLGSIEASLRRLTHYDYWQDKL
                     LPGILASSPADLLIYGMGEKPIKELVRRLKSGIPFNEIKNIRQTVYLADKEDAKDDDI
                     VLFSHEECLKDKLKQAKNFRYIEEESNKYNASRILQKVGKQVIVVNPPFPPMTEAEID
                     ASYDLPYTRLPHPKYKGKVIPAFEMIKFSVNIHRGCFGGCAFCTISAHQGKFIASRSK
                     ESILKEVKAITEMPDFKGYLSDLGGPSANMYRMKGKDERICAKCKKPSCISPVVCKNL
                     NADHTPLLDIYKAVDRLPEIKKSFIGSGVRYDLLLHRYADESLNKAAQTYTEELIARH
                     VSGRLKVAPEHTQDEVLKQMRKPSFSQFGQFKKIFDKVNRQYGLNQQLIPYFISSHPG
                     CTEADMAELAVITKSLHFQLEQVQDFTPTPMTLATEMYYTGYHPYTLEKVYTARSKEQ
                     KLAQRQFFFWYKPESRRQIMQVLQKMGRKDLIEKLFGQRGDMNPAPRKRR"
     gene            37121..38122
                     /locus_tag="ACZPB4_03155"
     CDS             37121..38122
                     /locus_tag="ACZPB4_03155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016275500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malate dehydrogenase"
                     /protein_id="HIR1097253.1"
                     /translation="MKTLTDEKLTIVGAAGMIGSNMAQTAIMMGLTSNICLYDPYAPG
                     LEGVAEELFHCGFEGVNITFTSDIKEALTGAKYIVNSGGAARKAGMTREDLLKGNAAI
                     AEEFGKNVKAYCPDVKHIVVIFNPADITGLITLLYSGLKPSQVTTLAALDSTRLRSEL
                     AKHFGISMDQVENCRTYGGHGEQMAVFASTAKVDGKPLTELIGTDALTKDQWAEIQTK
                     VTKGGANIIALRGRSSFQSPSYVSIEMIAAAMGGKPFRWPAGAYVSNGKFDHIMMAWE
                     TSITKDGVALKEVHGTPEEEAALEKSYKHLCALRDEVIAMGVLPAISEWHKLNPNIK"
     gene            complement(38207..39361)
                     /locus_tag="ACZPB4_03160"
     CDS             complement(38207..39361)
                     /locus_tag="ACZPB4_03160"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004497 - monooxygenase activity [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HIR1097254.1"
                     /translation="MKTKAIALFLLGFIPAFAQDIPTSKTEQNMDRIERCKKNYTELF
                     GGEALTGQGTDPEMMDILQKFIFGEVFRTGDLDKKTRELITCTVLATMQTLPQLNAHA
                     KAALNVGVTPIELREAIYLCAPFIGFPKTLNALNTINEVFKQQGIALPLERQATVTEE
                     DRHEKGQAIQSRLYGEGIKEAMRNVSGNMGPEVERFLTEFCFGDIYTRNGLDLKTREL
                     LAYCILTTLEAESQLHSHLEGNLLAGNSKETLTAAVIQCLPYIGFPSAIKALKIIKES
                     SQPAPKKNLVRLSKITVDPAQLERYNAFLEEEIEASMRLEPGVLTLYAVSEKEHPNKV
                     TILEIYADQDAYKSHIQTPHFQKYKQGTLQMVQELELVDSTPLIPGLKIK"
     gene            complement(39560..42052)
                     /locus_tag="ACZPB4_03165"
     CDS             complement(39560..42052)
                     /locus_tag="ACZPB4_03165"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HIR1097255.1"
                     /translation="MNRKTNLIPALLLSALSLYAMEDVKVTQFQHAGPFTVNKPILAD
                     SLNVNGKPFEAKNLLKATLPFEQTLANATVLDADTAGAITFAAPQKGYALHLFSFFLN
                     SDRYVKGTLDISGPGAFEVFVNDKPVGASSELVMEPRRYQVVVKYLTAETDTCPPSLK
                     ATFKSEAEAKVVASLNPEKRYTLLNILEGKDFQGVSVSPNGKYALVKYVNRYPEGKSE
                     SYGQLMDAATGRVLLQDGGFLTTAKWMPKSNRLYYTRTGLDGTELVTVDPSTYQQTVL
                     VPNLPKGRFVFTPDESTLLYTVEEEGPKEGTDLIRVLEPADRIPGFRDRSFIWRYDLK
                     TGLYEQLTFGHTDTYINDISADSRYLLFSTSDRVYTSLPHSRNSLYKLDLQTMAIDTI
                     WEKAPYVNQAAFSPDGKQLLVAGAGDAFDGIGRNIKQGQISNSYDGQLFLYDLASRKA
                     SPLTKDFNPNVIDAVWNRFNGQIYILCEDEDYQRIYTCDPANGKIKQVAASEDIIMSY
                     ALADNAPVLFYYGQSASNANRLYAYDLKGGKNRLVYDLSQDKLKDIALGEVHDWNFKS
                     DDGTTIQGRYYLPPHFDPNKKYPMIVYYYGGTSPTNRALEMRYSMHMYAALGYVVYTL
                     NPSGTTGFGQEFAARHVNAWGLKTADEIIQGTKLFCKEHSFVNEKKIGCIGASYGGFM
                     TQYLQTRTDIFAAAISHAGISALSSYWGEGYWGYGYCSVANAGTYPWNAPEFFTKQSP
                     LFNADKIKTPLLLLHGNADTNVPIGESIQMFAALKILGKTVEFVQVDGENHGIVGYQK
                     RIGWQNTIYAWFAKWLKDEPEWWKALYPDRTL"
     gene            complement(42064..42645)
                     /locus_tag="ACZPB4_03170"
     CDS             complement(42064..42645)
                     /locus_tag="ACZPB4_03170"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HIR1097256.1"
                     /translation="MNQIETFFDTMAERWDAVCVHDPGKIRTILDRTNLRQNARILDV
                     GCGTGILESYLLPYEPRQIVAIDIAGQMIEKARVKYPDHPLIEFLQEDAMSYEGKGFD
                     YIILYSAYPHFMRPERLIEHMSDLLVPGGKLVICHSESKEKINTHHHRHADRLSLPLP
                     PAREVAALMEPYLLPLVVEDTEQLYIVCGKRLS"
     gene            complement(42642..43457)
                     /gene="ispE"
                     /locus_tag="ACZPB4_03175"
     CDS             complement(42642..43457)
                     /gene="ispE"
                     /locus_tag="ACZPB4_03175"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050515 - 4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HIR1097257.1"
                     /translation="MICFPNAKINLGLNVVSKRPDGYHNIETIFYPIPVRDALEIVAS
                     DRTCFTQTGIPVDAPQEKNLVIKALNALKTRYEIPPLEIHLLKAIPFGAGLGGGSTDA
                     AFMLKLVNDFCGLDIHPDELEAIASTIGADCPFFIRNTPVFATGTGNQFEPVDLSLKD
                     YYLCLVKPDVAVSTPEAYSMVTPATPETSLKEIIRLPVSEWKERMVNDFERSVFPKHP
                     VIERIKDTLYEGGALYAAMSGSGSSVFGLFEKPTHFKEQSLFSDCFLWEGQLS"
     gene            complement(44095..44487)
                     /locus_tag="ACZPB4_03180"
     CDS             complement(44095..44487)
                     /locus_tag="ACZPB4_03180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIR1097258.1"
                     /translation="METTFTRRNSHGANLKRWREWRGIKQEVLADKIGVSQATLSGYE
                     KKDELEPEVLEKITKALDIPIEAITELNEGALINIYSGTWQDNATAAGSIQNQTFNPI
                     DKIVELYERLLKAEQEKVAMLHEIIKDK"
     gene            complement(45313..46728)
                     /locus_tag="ACZPB4_03185"
     CDS             complement(45313..46728)
                     /locus_tag="ACZPB4_03185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HIR1097259.1"
                     /translation="MIEKIHQKLSDSKVARWSVLALAAFTMLCGYFLTDVMAPLKPML
                     EEQLSWTSTEYGWFTSAYGWFNVFLFMLIIGGIVLDKMGVRFTGVASCILMIIGCSIK
                     YYAISDAFTMEGELFGWKAQVMVAALGYAIFGVGVETAGITVSKIIVRWFKGKEMALA
                     MGLEMATARLGTALALSITVPAAKYFGSISAPILLCLCMLCIGLIAFLVFCVMDRKLD
                     ASMDAIEQAEEEEPFRLKDILLIVTNKGFWLIALLCVLFYSAVFPFLKYATDLMVNKY
                     NVDPELAGNIPAILPFGTILLTPFFGNLYDRKGKGATIMIFGALMLIGVHLLFTLPIL
                     NQWWFATIVMIVLGIAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNIGLSMVPLL
                     IGWILDTYCKIDNGTGKPAYDYTIPMAVFTCFGVLALFIALMLKREDRIKGYGLELPN
                     IQKDADKAEAEIIAKEMIAEP"
     gene            complement(46752..48068)
                     /locus_tag="ACZPB4_03190"
     CDS             complement(46752..48068)
                     /locus_tag="ACZPB4_03190"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HIR1097260.1"
                     /translation="MTYEETLHYLYTSIPVFQHSGASAYKPGLGTSIALDDYLGNPHK
                     AYKTIHVAGTNGKGSVSHLLAAILRQSGFKVGLYTSPHLVDFRERIRVNGKKISQDYV
                     VDFVERHRSFFEPLHPSFFELTSSMAFEYFRDQQVDYAVIEVGLGGRLDSTNIITPIL
                     SIITNISLDHTQFLGDTEEKIAAEKAGIIKKGVPVLLGEAEKRSVFDLFQNEARKAGA
                     PFHYALSMGMLEGTGGLSMVHWKFPSVEYGEVIGELAGEVQQANAITVFSALHLLREK
                     CGVDILPEAVHEGFGHVTQLTGLMGRWQTLRTKPTVICDTGHNVGGWKHIAEHLNAMR
                     SRFREIYMIVGMVNDKDIDGVLSLMPPDASYFFTQASVERAMPVKDFAMKAMRKGLPG
                     VLCETVEEAVEKALKSADKDDLIFIGGSTFIVADALPLFMKEDEYK"
     gene            48152..48409
                     /locus_tag="ACZPB4_03195"
     CDS             48152..48409
                     /locus_tag="ACZPB4_03195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HIR1097261.1"
                     /translation="METRRITYTPQGGVCSKLMVIDAKEDVIENVQIVGGCHGNGQGM
                     CALLKGMRIEDAIGRLSGIDCHGRGTSCPDQMAQALKQFNR"
     gene            complement(48399..49082)
                     /locus_tag="ACZPB4_03200"
     CDS             complement(48399..49082)
                     /locus_tag="ACZPB4_03200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HIR1097262.1"
                     /translation="MEKIKVLLVEDEPTLAMIIKDTLDGNEFDITLAANGEEGLSRYA
                     EINPDIIVADIMMPKMDGFTMVKLIRKTDTHTPVLFLSARSAANDVVEGFETGGNDYL
                     KKPFGMAELIVRIKALLHKVSVQRPEATSFRIGLYTFDSITQTLVYRGEKQLLSNRES
                     EILKRLCDNKDQVLPMEEILIDLWGDDSFFNARSLHVFITKLRHKLSKDESIKILNIR
                     GIGYKLIID"
     gene            complement(49107..50627)
                     /locus_tag="ACZPB4_03205"
     CDS             complement(49107..50627)
                     /locus_tag="ACZPB4_03205"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1097263.1"
                     /translation="MNIRLRFKLIALLIVLSLAGLLVFQGYWLKGLYDTLYKQMEINI
                     EEAMKIADYKELFLRIRSIKKEQGALGPQTQDVYFSSELDPSNKQKMDAKASIHPQKE
                     DPDLNREDIFKTANPDSHMKLHIDYGDEEDFSSIDSTLTDYLYVIGEVEDMVQQAMHA
                     NIDSIKPIDFKTYNKLLTSELEARNIVTEHELVTIYKPNNGDEKGWMHLDKPERFTTW
                     KNPVHFDYPLHNESTLQYRLFLKSPASVILTQMKGILISSFLLLLLIICAFIYLLRTI
                     LKQKTVEELKTDFTNNMTHELKTPISVSYAAVDALLNFSDPVNEKQKKYLTIVKDQLI
                     HLTGLVEQILTLAVENRSTFRLRPETISLNELVNSLIEQYKLKASKPVEFTCSIPEDI
                     ELVADRTHLYNMLSNLIDNAIKYADKEPCRIEATARQDDHETTISITDNGPGISEANQ
                     RQIFDKFFRVPSGNIHNVKGYGLGLYYVKDMMGKHGGTARVESVPGKGSTFTLHFK"
     gene            complement(50711..53092)
                     /locus_tag="ACZPB4_03210"
     CDS             complement(50711..53092)
                     /locus_tag="ACZPB4_03210"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hybrid sensor histidine kinase/response
                     regulator"
                     /protein_id="HIR1097264.1"
                     /translation="MEGRETDLEYNLLMGLTGASVSKHLLDEHFTLLWANDFYYDMIG
                     YPKEEYEALFHNKPDLYFKGYDEAWNILSKNVYETIANKASGYETVIQMPTRKGKRWT
                     KITSTFTDQLQDGIPISYTVMTDVEDVMRRRIEQTITYDNIPGFISKHKVHKDGSFTL
                     LEANDKYMDFSGIDKNSFLSFSPFSRLDETSRNTMNAHIPCMLKGEPVHFVIQSKDKN
                     GNGAWLQLNGECIGWEGDEPIYLIVYINITDITEQRELQKKLEKQSKQLKEALKSAEQ
                     ANQAKSDFLARMSHDIRTPMNAIMGMATIAKAHVDERERILDCMEKINGASKLLLSLI
                     NEVLDMSKIESGRLILSEDEFNVGELLQDLVVMMQPEIKNKQQTLNIHVKNLRHENVK
                     GDTQRIKQVLMNILSNAIKYTPENGRITIEIYEKDPHNGIGNYQFVFEDNGRGMKPEF
                     LDKIFEPFERASDDEIKRIQGTGLGMSISHKIIQMMGGDIKVESEYGKGSRFTIDMPL
                     VCRDQKPDDKIEVEGLEVLVVDDDKIACLNTSSCLREIGINSECVYSGSEAIEKVRQH
                     HLAEKEYFAVIIDLKMPQMNGIETTRQIRRFVGADVPIIILSAYDLEEYEAEAKEVKA
                     NGFITKPLYKSKLLQVLRSFLDKGDQPEPIRPFKLSNADYSGKRILLVEDNELNREIA
                     VEIIGSTGITIDTAINGLDAVHKVAQSEEGFYQIILMDIQMPIMDGYEATRQIRSLQR
                     RDIAHMPIIAMTANAFSEDVTNAIKAGMNYHLAKPIDIGALMGILSKYLQAPA"
     gene            complement(53188..54069)
                     /locus_tag="ACZPB4_03215"
     CDS             complement(53188..54069)
                     /locus_tag="ACZPB4_03215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIR1097265.1"
                     /translation="MDKQFLCLDSPTDFMVGKYISADELKEFINIPCKIKAGVFILCM
                     EGQIRSTINMSELTTSKLNVVTLLPNSRIQIHEISPDILIYFIAFSFDFMCYANFIKS
                     TMGYLLMIYRYPIIKISQNRANLITNFYELLYQYAVYPDILNNKEMIKAIFMMCSQGI
                     AEIYSKNYPLEKQELTRPLQIYQEFLNMVLRYYTKEHNVSFYAEKLGLTFSYFSTSIK
                     KAIGETPQEILTQTIIIDAKTQLKGTNQEIKNTAMDLGFNNLSFFNKFFRRNVGMTPQ
                     EYRGKSYTYSCYQKTSD"
     assembly_gap    54202..54301
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(54370..55356)
                     /locus_tag="ACZPB4_03220"
     CDS             complement(54370..55356)
                     /locus_tag="ACZPB4_03220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HIR1097266.1"
                     /translation="MCTRVVYSGTNGMVATGRTMDWKTDMHSNLWVFPRGMERNGETG
                     KDSLKWKSKYGSIITSAFEIASTDGMNEKGLVANLLWLPEAQYPARDKNKPGLAITIW
                     VQYMLDNFATVEEAVSFINEDTFQVVSDKMPDGSRLATLHLSISDATGDCAIFEYIGG
                     KLTVYHSKEYKVMTNSPTYNKQLALCEYWKSIGGLSFLPGTNRASDRFARASFYIDAV
                     LKTDDEKIAIACVFSVIRNASVPYGISTPESPEISTTQWRTVSESKNLIYFFESSLTP
                     NTFWVRLRDMDLSEGAPVLKLSIANGETYHGNTSKDFKPAQPFKFMGVKDLI"
     gene            complement(55441..55521)
                     /locus_tag="ACZPB4_03225"
                     /pseudo
     CDS             complement(55441..55521)
                     /locus_tag="ACZPB4_03225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005797789.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
     gene            55705..58071
                     /locus_tag="ACZPB4_03230"
     CDS             55705..58071
                     /locus_tag="ACZPB4_03230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane beta-barrel protein"
                     /protein_id="HIR1097267.1"
                     /translation="MKRTIYYMILCLLMSLGEIMAQGISGKVMDGKEQPIDGVAVILQ
                     TLDSVYVDAVVTDTLGDFRLNHPLDQSYRLIFQHILYNTIGKKITTANVGTVVLEEKD
                     YQLAEITVKGERPQVKLEGGKLTYDIPQLMKDKTATNAFEIIKDLPGLIERNDNLELV
                     GASRLNIILNGQLTTMSADQLIQLLKTMPASRVEKAEVMYNAPAKYNVKGALLNVVLS
                     KNESETPSWQGETGVDYTQYRHAGGDAHVNLLYTNKGFSLDFLLNGNKRRDVMGEDML
                     ARHTLNSGMTEISQHNRALVHVNRGTVRLGMDYTFANEDKLSLAYYLKGDKVLSDRDA
                     FTSYLDLSKPENKSESTSLVRDDGHSAIHNIRLQYDGHAGISAGADFTRYHSPSVLDY
                     HDTNTNGSRTDMINNTRQDVSRWSVFLNKTHSFASGWGLNYGVHGGYASSKNYSEYLY
                     EQGAGYEMDEEALEDNTQKEYIADIFAEVSKSFGERFSATVGLKGEYFKSDYTSSREN
                     MNLWNEGALFPTVSLSYTFSPRHILQFDISSDKTYPGYWQVSPQVTPLNSYSEVAGNP
                     LLKPYRTYEGQMVYIFRQKYMLVAFCEYTPDYFAQLPYQSDTELKTVFRFENMDYSLE
                     TGLAVIIPFNVGRFWNSRITLRGWRMQEKNDNFHGISYNREAYLGLAHMSNTFNLCDK
                     PNLKMTIDGQYVTPGAIQGIYDLGSMYEISAGLKWTFLNDRASLTLKGDDIFASSIPR
                     TIKINQGNQWSRMRKLNDERCLKLSFVWKFGGYKERKHDSIDTSRFGK"
     gene            complement(58148..58759)
                     /locus_tag="ACZPB4_03235"
     CDS             complement(58148..58759)
                     /locus_tag="ACZPB4_03235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarC family protein"
                     /protein_id="HIR1097268.1"
                     /translation="MFTNFNFQQILSAFIVLFAVIDIIGAIPIIIDLKDKGKDVNALK
                     ATLISFLLLLGFFYAGDILLRLFHVDIESFAVAGAFVIFLLSLEMILDIEIFKNQGPI
                     KEATLVPLVFPLLAGAGSFTTLLSLRAEYASMNIIVALVLNMLWVYFVVRMTRKVEKV
                     LGKGGIYLIRKFFGIILLAISVKLFMSNITLLMEQIEASTKAI"
BASE COUNT        15021 a        12931 c        14003 g        16800 t
ORIGIN      
        1 aaggattctc aagtgactcg cataggattc aaacctataa ccttctgatc cgtagtcaga
       61 tgctctattc agttgagcta gcgagccaat ctgtaaatga atttgaatat tcaagtgact
      121 cctaaaggat tcaaaccttt aaccttctga tccgtagtca gatgctctat tcagttgagc
      181 taaggagcca agatatattc tattgctatc ttcgaatggt gaccgcgaca ggattcaaac
      241 ctgtaaccgg ctgatccgta gtcagctact ctattcagtt gagctacgcg gccattgttt
      301 cgtgattgcg agtgcaaagg tacgtttttg ttttaaatat gcaaacgttt cgactacttt
      361 tttgcgaatt taatctaaca tttttggatt gaagatcaga taaccaatgt ttaagccaaa
      421 gttgaaattc tccttcggat aactgtatcc gttggcgtac agacttatac ataaaaatgg
      481 caattgcaat acgaccgccg cttcacccat ataattaaac gagtgcaaaa acttaccata
      541 atgcgggatt ccgacatacg ggttgttttc cggcaccgtc ttttgtattt catagagcgg
      601 agcgaagcca tacatatcca accggaagtg cagaagcttg cttaacttca agatcgggga
      661 aagcccgaaa gccacatatt ggttcgcccg gaacgcctcg ttgaatacaa tctcgctatg
      721 gggtgtcggg gtaaacgccg gggcctgtaa tacgctagcc gtatagttat tcatgaggtt
      781 cttgctggat atgaccattt ccgccaaata acctaagttg aaacggttgc tcagcgtctg
      841 gtattggttc cagcgccctt tcagttgcag ccagctatgc actttgcgac caatcggggc
      901 ttccgtcgtg gcggaagtgg gggatggagt gtacttctcc gtaccggtta cgtattgggc
      961 gattaggaat tgctgctttc cgcttatcgg gtattgtttg gtgttgagtg agttttgctc
     1021 gatacttaac gaaccactga ataaatcgta ccagctatgg tcgaaagagg cgttcgggaa
     1081 aggtatcgtg gtgctctgca aatagaaatc gttcagccgt ccgtaggcga acccgatctc
     1141 cgctttcgcg tggttgagga aggggaagcc taattttagt ttcatgtaca gttctttctg
     1201 cttaatcatg gcgggcacta tatcctcata aaagagggat tggctttccg tgtatttctt
     1261 gtccgagaag actccttgcc aatttaaata agtggggatt tgcgtttgca ggtacatccg
     1321 gccactcaac atgacaccac taaaggagtt gcccacttga aagttcgagt ttacgtcggc
     1381 ggcgaaccgt cccagatatt gataccccaa tcctaggtat aattgattcg cttgatgaga
     1441 cgatacgttt ccaccgaagc caaccgtgat ctcttctttc atcttcacgt ccagataaag
     1501 atcgaatttc ttctcttttc ggttataaac ggcatgcggc atgatttccc taattttgga
     1561 ataggtcagc atcttgaaat aagcccgctt gaactcttcc atggagaact cgttattgat
     1621 atccctgtgt aattgggcct ctatgtattt acgctgggcc tcggatacgc ccgtcacgta
     1681 aatattgcgg aagatcagcg ggggaaggtt ctctttatag gcttttcttc tttcggtaac
     1741 ctcatttaaa ggcacttccc ggggaacccg ttgcttgatg gagtcgatca tggaaagggt
     1801 acgtttatac ccgatgtcca taagctcctt acctttctgg aaatccaata aggagacggt
     1861 aggaaaactg aatttaatca tcatgccatc ttcctccggt acctcgtaat cggtcttttg
     1921 catgatcatg gtctcgatct ggttataagg attctccgaa ggctttttat tccctcccga
     1981 taccgtcgat ccgaaaatga aatccgggtg gaacgcatct ttcatcgggc ctaccgggaa
     2041 attatcgtag atacctccat cgaataaagg aatactgtct ttccatatgg gctggaagaa
     2101 aaacgggaaa gtcatggagg cacgtacggc gtctcccaga tccccattct taaagatgat
     2161 cggcttttta gtatatatat ccgaggccac gcaacggaaa gggacaaaca ggttgtcgaa
     2221 attccacccc gcctttgccg tcgcctgcga gaacaaggcc atgaacgcct gattcatctg
     2281 tatgggattg attaagcttt gcggtaagaa gctagccttg atctgtaggg aatcggacat
     2341 atcgatggag aaatgcgcga attccggggt cgggtaaggc tccttgaaat aataggtata
     2401 ttgctcctcc accgtacctg tttgccaata ggcgaactcc ttggaaagca tcagctccag
     2461 catctcctcg ggggaatacc ccatggcgta taaactaccg ataatcgccc cgatggaggt
     2521 accggtaatg taatcgatcg gtatattatt ttcttccagc gccttgatca ctccgatatg
     2581 tgccgctcct ttggcaccgc cgccactgag taccaaccct actttctggg cggaaacaat
     2641 ctgaatggca gcaaggaata aggctatgat aactgttatt ttcctcatat gaacccaatc
     2701 tgtttttctt ctccaaatgt aagaagtatt tctttagaaa cataaacatt ttgttttttc
     2761 gtattgttga gttatcaata caattaaaac agatgatgtt atgaaagaga aagaattgaa
     2821 tagggaagag cggaataaga ccgttatgga gaccggtgct ttggtcatgg ctgagtttta
     2881 tgcggattgg tgccctcatt gccagaaaat gatgccgatc gtgaaggagt tcaaggaatt
     2941 ggagaaagga aaattagaag tggtacaaat caatatcgag gaggagagcg ctcttgccga
     3001 tttgtatacg gtggaatcga ttcctacttt tatcctgcta cggaaagggg aggctttgtg
     3061 gagacaatcc ggcgagatga gcttggatag gttacggaaa gtggtcgagg atgtcgtggg
     3121 ctgaaactaa aaaaaccgtt cccccgagaa ggaacggttt tttatatatg tgaggattgg
     3181 tttatccgat cagttctacg ctacgtttga tgaattggct taaggcctct cccttcagca
     3241 taccgtttcc taacaaagca aggtcgatca actgactaac tgtcttgttc gtgccggcgt
     3301 actcggccag aacttggttg cgttgctcac gaagctcatc cagcttatgg tcggtgttgg
     3361 tcatatcctc tttctcttgc gccgtgatct catcttcttt ctttttgctt tgagcctcac
     3421 gtaagtcggc ttgacgagcc tcccatcctt tgatatcgct aaggatcggt tttaacttct
     3481 cgtcgcaagc ttgctcctct tcagttaata ctttcttgat caatggatga tccgtattca
     3541 atacgaagtt gaagctatcc ggcatctcgc catagaaaga catacccggt tgcatagcgg
     3601 acatctcacg cattcttcgc atatactcgc tttgtgtcaa catgacaggg ttcgcgtttt
     3661 cgcccaatgc ctcgaatgtt acgtagaact cggtcttgtt caatttcggc atctgactct
     3721 tgaatacttc ctgcatggcc gttttctgct cctcgctcaa ggttacctta ttcgagtctt
     3781 ccttgcggat caggttatcg atcgtatcgc tatccacacg aacgaagcgg ctcttctcga
     3841 acttctgctc caattgtccg atcaagtgta catccaattg tccgtccatt tccaagacgc
     3901 tgtaaccttt gtcctttgcg gcttgtatat agctgtattg ctcgtcttta ttggtggtat
     3961 acagatagat taagttaccc tctttgtctg tctggttgtc cttgattaag ttcttgtatt
     4021 cctcgaaagt gaagtatttg ccttcgacgt ccttgaataa ggcgaactta accgcgcggt
     4081 cgtagaactt ctcatcagtc aacataccat attggatgaa tagtttcaag ctatcccatt
     4141 tctcctcgaa ctgcgggcgg tcgttcttga agatctcttc caagcggtct gccaccttct
     4201 tggtgatgtg gttggagatc ttcttcacgt tctgatcgct ttgtaaatag gaacgggata
     4261 cgttcaacgg gatatccggc gaatccaata caccatgcaa taatgtcaag aactcaggaa
     4321 cgataccctc tacggaatcc gtaacgaata cttggttgca atataattgg atcttgttac
     4381 gatgcaagtc gatattgctc ttgatgcgag ggaaatataa gataccggtc aagttgaacg
     4441 gatagtctac gttcaagtga atccagaaca acggctcatc cgtcatagga tataagtcac
     4501 gatagaactt cttgtaatcc tcgtcggtca tatcggccgg tttgcgaacc catgccggtt
     4561 tggtgtcgtt gattacgtta tcttcgtccg tatctacata tttgccatcc ttccactctt
     4621 gcttcttgcc gaatgcgata ggaaccggta agaaacggca gtattttgtc aataagccat
     4681 tgatcttatc cttgttcaag aaatctttat tctcgtcgtc tatatacagg ataatatcgg
     4741 taccacgatc ctctttcgtc gtttcctcca aggagtattc cggtgtaccg tcgcagctcc
     4801 atttcatggg aacagcgcct tctttgtacg atttcgtcac gatctctact ttcttggaaa
     4861 ccatgaaaga ggagtagaaa ccaagaccga agtgaccgat gatagaagcg gcgtcgttct
     4921 tgtatttctc aacgaactcc tcggcgccgg agaaagcgat ctggttgatg tacttatcga
     4981 tctcctcggc tgtcataccg ataccccggt cagagatcgt gatcgttttg tcatcgaact
     5041 taacctgtac ggtcaaatcg ccgagttcgc ctttaaactc gcctacggaa gaaagcgttt
     5101 ttaacttctg ggtagcgtct accgcattag aaacaagttc acgaaggaag atttcgtgat
     5161 cactgtataa gaacttcttg ataatcggaa agatgttttc cgatgttact ccgatgttac
     5221 cttgtttact gctcatagtc tgaatatctt attattttta ttgttatttt gtgcgtattc
     5281 ctgatcctga tcattctcaa gatccgccta ttcctataca aaacgaatgc caaaatgttt
     5341 cggataaact ataaatgaca aaaaggcaga tgccggctga tagatttgca gccgagcata
     5401 gtttgatcaa accatatcat ctcctgtctt ggcgaatgta acacggatgg ttttatggaa
     5461 tgggataaaa cgagatacga tcgctatgaa taaggagatg actaataaat accccagtat
     5521 ctcttttaac gccaataata agctttgttg ctgtaacgta ttatagagtg tattggtagc
     5581 catttgcgct gcctcgtcgt agggatgccc ttgggtcaag gcgttgccaa gcgcctgatt
     5641 atagcgtgag gcggctagag gatcggccag cgtaacggtt tctgataagg aatacatata
     5701 tttttgttcc aagcgatata gtatattact gtaaaaagaa gtcgccatga taggggatag
     5761 taccgaacgg aaaatgatga gaaagaaagc gtttgacaat aaatatttag gatttaaatc
     5821 ttccacggca aataaggcga aagctatgat tagaatcatc atgcccaatc ccctgaggaa
     5881 tataggaaag tagagcatct cgtatctgct atccggtgag atcccgaaat aaaggctccc
     5941 gaagaacagg acgaaacaac tcattcctcc cgctatcaag aaacgaaacc gccaacgttg
     6001 ccaccggaac caccaaaaac agatgaacgc ccccaagaca tatcccggaa gcaaataagt
     6061 ataaagggaa taggtatggg tactgtctac ctttaagata ctggtcaggt agctggtcaa
     6121 caaggtagtc gaagtactga aaaacatgac aagcatcata tagaaataac cgataatggc
     6181 tttcggctgg tataaaggcg ccagattcac gtacggacgt tccgaatgat attgatacca
     6241 aataaataaa gcgatcaata tcggggcgat catgatataa aggcaaatct tgggggatgc
     6301 catccagtcg agtactttcc cgtaattaat gacatacata agcattaaca atccggtgga
     6361 tatgatgaac atttcccgga tgtgtagatc ggccaagggg atggacttga tcggccggtt
     6421 atggcggaag ctgatgatta ccattactat ggccaataaa atcattagca tcatgaagta
     6481 atacatatat ttccagtcgt aatggtaggc taactgtgcg gtaacaagca tggatgcttg
     6541 tccccctccg aaaacaaaag gatagaagta agaatagaat tggctacgta tatttttagg
     6601 gctgaatatc ttttgcgcgt accggataaa ccacagcatg agaaaccctt tcaggaaacc
     6661 gatcgcgaaa ctacagacga tcaatatgtc ggcgttctgg gagcgggcac agatccagct
     6721 taggaagaac tgggcgacta aatccgccaa caataagaat ttgatggaga aggcttccag
     6781 tatcttcggg ataatcggat aggataccgc cattcccgcc gctgccgcgt aatatcccat
     6841 ggttatatcc tcggtgttcg tgcctagcgt gtttgatacc tccagcatac tgccggtgta
     6901 cgagccgttt agcatcgtga ccggaaggat aacgatgaag atacagatca atcctaacca
     6961 gtccggcacc cattggcgga tcggtgcccc aagctctttc atcgtgatca tttgcgtaag
     7021 gcttctgttt caaccatcat gcctgctctt aaatattgcg tatcttcttg cgatagattt
     7081 tccaagtcta tccgtaccgg gatacgttgt tgtaccttga cgaagtttcc ggcggaatta
     7141 tcggtcggga ctaatgagta tttggagcct gtggcgtcgg agattgcggt tacctccccg
     7201 ttgaatatct ttcccggcaa cgcgtctacc ttgatacgta ctttctgccc gatatagatg
     7261 tgggggatct gggtctcctt gtaattggcc gtgatccatt tgtctttatc tcgtacgagg
     7321 taggatatcg tttgtccggc ttgcacgtat tgtccgggct ctaaggtccg tctgcctaca
     7381 tgaccgtcgt aaggggcggt tataacggta taggaaaggt ttaacctcgc taaatccaga
     7441 tccgcttctt ttcgtaagat cgccgcctcg gctcctgttg tcttcttgct ggtttcggtg
     7501 aattgggaga aagcggcttt cttttgttcc accaacgcct gatatcgggc ttgcgccgcc
     7561 tcgaaagcgg ctttggattg ctcgtattgt tgctcgggga ccgattcttc tttcagcagc
     7621 cgctcaaatc ggtgataatc ctgttccagt tgccaaagct tggctttagc ttcggcgatg
     7681 ttggcgtctt gtacggcgat gttcgtatgg gaggtctcga taccggaacg aagtacgtct
     7741 tgtgatcctt gggcatcgat caacgcggcc tctgcctctt ttaccttgat ccgatattcc
     7801 cgatcgtcca gtatgagaag tgtgtcccct tggtgaacgt actggtgttc cttgaaacgg
     7861 acctctttta tgtagccgga ggcacgtata tttagtgggg cgatatattg gtccacaaag
     7921 gcatcgtttg tcacctcata attgatgtaa cgccagaaat aattggctgt ccaccaaatg
     7981 ccggaaccgg ctaaaaggat acatatggag tttaatacta tattccgtgt ccttactttc
     8041 tttagtcttt gatgtttctc ttttaattcg tttgccatag tcgttgtttc tttttagaga
     8101 cggccgcaag ccttctgtag ttgatagtaa gtgtaaatta cgtgggtacg ggcattcgtg
     8161 agctgtagct ccgcgttgag gagaaccgag ttcgcatcga gtaagtcggt taggatcgcc
     8221 aattggttta aataccggtt ttgcatgatc ctgtagttct cttgagcttg ccgtacggat
     8281 aacttcaagg cttccacttc ttgtagagct tccttatgac gtaagaacgc ggtgcgcact
     8341 tctatacgga ttttctgttt tttctgttcc tcctcgtttt tatgtaacga gaccatccat
     8401 ttgctttcct ttattttatg gttgttttta tataaagagg ataaagggta ggagagcgac
     8461 agtcctatgt tccagttgtt attgtacata tccgctaatg ttcgggagac tggacgtgcc
     8521 aatgtgttcg acgcatatag cgataggctg ggtagcgagg aggctttagt caaacgtata
     8581 tcattttggg ctaactctgt ttgtttccgg agtagacgta tcgccggatc attggaatag
     8641 gcttgggcta cataatcttc gtaagtttct aaagatacga tttggtccag taacgtggta
     8701 tctggtttga gcaatagatt ttcatcgaga ccgatcagga tatccaattg ctgtgatacc
     8761 agtatgaggc tattatccgt ttcttgcaag gataggcggt cgttggttaa ttgcatctcg
     8821 cttcttaata cgtcgttatt ggttatcagt ccctcttttt tcatacgccg gatatcttgc
     8881 aggcggcgtt ccgattcctc gatattacgg gaaagcacct cacgttgttt aaacaggctg
     8941 aaaagaccga tgtattggtt taatagaccg agcttgatct cactctggtc tgtgagcgtt
     9001 tgtaaagagg cgacttcttt ctccagatcc gctttccgga tggaataccg gattttaccg
     9061 ccttggtata tcggttgggt aaggtcgatg gcatagttct gggaccaatc gggcgcttcc
     9121 gggcgagtcg gatgggcgag tccttgctca aagaggatcg gttgccctac atatccacct
     9181 ttcaagccga tttgcaggtc tggcaattgt gcggaacgtg ccgtatgggt tctctcttgc
     9241 gctatcgatt cttttaagac gtctgcttgg atctgcagac tatgccgtac gcctctctcg
     9301 aaaagctggt cgatggtcaa gaagagcgaa tcggtttggg cgattgccgg aaatgtagcg
     9361 accgtcatac aaaagaggct caatacgtgc tttttatata ttctcaagga cattatgtac
     9421 tgcttttaat tcggataaca tggtttctac gttctctatt ccgataatat gctccgcatg
     9481 tacataaacc tgatcaagga tcgggcgaat ttgctttttg aattcttctc cttccggggt
     9541 taggaaaacc agtttgttcc tccggtcctc gggatcttct ttccgatgga cgtagccttt
     9601 cttctctaaa ttgttcatta ggtttgtcag acaagcctta tcctttgccg ttctctctgc
     9661 caagacctgt tgggtgatac cttgttcgtg ccataggcaa ctcaagattt gaagcatctc
     9721 aaatgttata ccggcgttgt tctttttcag cgttcgttgc atagaccgac gaaatgccat
     9781 gcgtgtgcgg acaacttgta acataagttc ccggaattct ttaccttcta ccattactta
     9841 taattctttt aaacttgctg ggcgcgaaga tagcgttttt tcttggatta gtcaaatgtt
     9901 taactaatta gcgtctcgct aataaagtat gtttgccatc taggtggcac agctttgcca
     9961 tcggcgtggc acgggcttgc catcactatg gcacgggtat gccatcagtg tggcacagct
    10021 gtgccaaggc gatggcagat gctggcacag tatgtgtatg aaagacaggc gtatagactg
    10081 aaagcgtaac aaacccgtgg agtgattcgt tacgctttct gtttagttct cgtttacgag
    10141 tttaagatgc attcttcttt atccaaacgc ctccttcaat tgcttcaccc atcgctcgat
    10201 tcgtttgtcg gtttgatccg gttggttttc caaatcgagg actaagccta gtagtttgcc
    10261 atttttcaag gctttggagg cattaaaaaa ataatcatcc gaagaggtct cgcctactaa
    10321 agtcgcccca caggaggtga aagcgtccgc caatatgccg actccatcgg cgaaattatc
    10381 cggataattc gtttgatctc caagaccgaa aatagcgacc ttcttatttt taaggtctaa
    10441 agtgaccagt tccgggatga tctcgtccca ataggtggga agctcgccat cgaaccaagt
    10501 agaggttcct gcgattatat ggtcgtaagc ctcgaaatct cttttccatg cgctttcaac
    10561 agggatgata tcgatctgat cctccccgaa agcttttctt attttattgg cgacaaaggt
    10621 tgttttctct gtgcccgttc cgtaaaataa tcctgttttc attatgatgc ttttaaagat
    10681 ttaacgaatg tggatctaat aaagcagcag ttcttttgcc gcatgataga tggtctcctc
    10741 gttggggagg atggcccgtt ccaagaccgg atggaaacca accggagtga atagggaacc
    10801 tacccgttgg atcggagcat ccaagtactg gaatagttcc gagccgatga tgccggcaat
    10861 ttccgctccg aagccagaga agaccttgtc ctcatgtacg atcaatactt tactggtttt
    10921 cttcaccgag ttgaagatcg cctctttatc caatggtatc aaggtacgaa gatcgataac
    10981 ctccagttcc cagcctttct ccttgtaaag aagctcggct acgttgaggc aaagatgggt
    11041 cgtattgcca taagtgatga ttgtcagatc ttttcccgga cggcggatac gggctttccc
    11101 aaacggaacc tcgaaatcct cggggacaaa ggtggaggct tctaccgcat tgtaaagcgc
    11161 tttcggttcc agatagagcg taaagccttt agaacgcata ctcgtccgca acagtccggc
    11221 ggcatcatcc gcgaaagagg gataaacaat ccgggcaccg ggtagtgagg tcaatgcgcc
    11281 ctcgatggtc tgggaatgat aaagtcctcc tccgatatag cctccggagg ctaggcgcaa
    11341 agtgatgttt ggggtaaatt gcccgttgct gcgccaatac tcatgcgtac attccacgta
    11401 ttgctcgacg gccggccaga agtaatcggc gaattccgcg ccctcgatca ctacatggat
    11461 cttcgggtca aagcggcaca taccgttcgc tgtccctacg atataatcct cggcgatagg
    11521 ggcgttgaag actcgctcga taccgaattc ttgctgcatg cctttggtga tgttgaatac
    11581 gccacccttt tctttattgg ctacatcctg tccccagata aacgtatccg ggttgtgccg
    11641 gaactccgct ttcaacgtct tgttgatcgc cataactagc gtttctttct ctccttcctc
    11701 gttttgaaca ccttctttgt atttttgagg ttgataaggt tccggaagga cgtaatcctt
    11761 gacggtagac ggatcgggat cgggggcggc catcgctttc cgattggcgg ctttcaggtc
    11821 tttagccgct agatccgcga tctctttcaa ttcttcctcg gtgaaacgtc cgtaacgaat
    11881 cagcatgcga tggaatttgt ataaaggatc ggcggatttt acataggtaa gctcgttctc
    11941 atcacgatac aaggtatgtt tatcggagtt tgagtgggag cctatccgta cgcaattggc
    12001 ctgaacgatt acgggagtcc ggttggcgat cgcgtactct ttggcctcgg tcatggcatt
    12061 catggaatcg aacacgtctt ttccattgca atggataata cgtaaattct tgaagccaga
    12121 gaagttatcg gcaactttac gattggccgt ctggtccttt ttggggacag agataccata
    12181 tccattgtct tggaagacaa agataaccgg cagtcgctca ttgctggcgc cattgattgc
    12241 ctcatacaca tagccttcgg aagcggccga ttcaccgtgc gaggtaatcg ctacgccttt
    12301 ctgtccatag taaaccatcg cccgtgccac gccggcggca tggagatcgt gagtcgccgt
    12361 agcggaagaa acgttctcga tatgccattc catcttagag aagtggttag acatgtggcg
    12421 gccgccactg gtcagatcgg tcgccttgga gataccgttc aggatgatct cctcggcagt
    12481 cattcccgcc gagagaaccg tcaacatatc ccggtaatag gggaagagaa agtccgtatc
    12541 cttatcgaat acttgtccca tggcgagttg tatcccgtcg tgcccggcat acggggcatg
    12601 ataagaccag ccgagagatt gcaataaata ggagggagcc ttctcatcga tcgcccttcc
    12661 gagcgtcata aggtaaaacc atttcctgag agtctcctta tctgttgttt ttatatcata
    12721 ctttttcatg ttgttctatt ataataatgt attaagcgtt ccaattctct agttcgtcgg
    12781 cgatggaacg taaaaaggct cccgccaaag ctccgtccac gatacgatgg tcgtaggaga
    12841 gtgagaggta catcttgtga cggatagcga tcgtgtctcc ctcgggcgtc tctactaccg
    12901 caggcttctt ctcgatataa ccgacggcta ggatcgctac ttgaggctga ttgatgatcg
    12961 gggtgccgaa cagactcttg aaggttccga aattcgtaat cgtgaacgtt ccgccttgga
    13021 tgctatccgg ggcgagctta ttctcacggg ctttagccgc caaggtatct atttgtgagg
    13081 cgaggccact taggttcagc ttatcggcat cgtgtataac cgggacaatt aaatttccgt
    13141 cgtttaagga aaccgctata cctatattaa taggcttctt taggatgata ttgtaaccgt
    13201 ccacagatga atttactaat ggataggctt tcaacgcttt ggcggtcgct tcggtaatag
    13261 ccggcatata agttaggttg atgccttctt gcttgaagaa ttgatccttc acttttttac
    13321 gccagttaac cagtcgggtc acgtctacct cgataaccga cgtcacatgc ggagatactt
    13381 ttttcgataa taccatatgg tccgcaatga tcttacgtac acgatccatt tctctcacct
    13441 cgtctccttg agcgagtgga gcggatggag tggccgctgt cataggcatg gaaggagcgg
    13501 tcggcggcgc taccgtaatt atcggcgtgc tcgtagccgt ttgctgcatg gaagaaacag
    13561 gagcctgttt cggtttcggc atttccgtac ctttattttt gtgatcgata tacgtttgaa
    13621 tatctttctt actgagacgt cccagatatc cggtacccgg aatatgatcc agttcatctt
    13681 gcgatacacc ggcagctttc gctaattgca atactacggg agaataccaa cgatcttcct
    13741 cttgggaatt ctttgataat tcctctgagg cgggagcggg gacttgttct ttcggttgag
    13801 tagcctccga ggtttccggc tgagctccgt tatcctctcc ttcaccttcg atctcaagga
    13861 tcgctacgac tgtaccgacc gctacggtgt ctccctcatt aaaaagaagt tgttttactt
    13921 ttccctcaac gggggatgga atctcagcgc ttactttcgc tgtgcttact tcgaaaagga
    13981 catcatcttc ctctacggta tcacctacct ttaccgacca tgagatgatg gttccttctg
    14041 taatactttc gcccaactta ggcatcttta tctcaaatgt agccatattt tgatttttta
    14101 attactgtca tatagtggga gacggggcgt accccgtctc tacaaacggt atataataag
    14161 aacaaagatt aagaaggtaa gtttctgtat tatagtgtat aagtgttaaa gttccagctg
    14221 gctgtagcat atttctgctc tttaagccta tagatggctt ccaagtctgc ttgcgtgaag
    14281 gaataatcct gtatgcccgg attattgatc gtgaaataat aaagaagcgc tttcttaaaa
    14341 tgctggatgg agatagatgc cggaagatga gcgctgatat tcgtgaccgg actccgtaca
    14401 gatttaacga atgtcgatcg tttgcctcct gttttctctg gtgtttgacg ggatgtactt
    14461 ttcaaggagg tgacgagcct atccagatcg gtggaaaaca ataaggtagc atggtgcata
    14521 taccgattct tatggatact ctgtgcgcta cccgatattt taaatcctcc gatagttagt
    14581 cctttccgtt catccatctc gacatgtact cccaatgtct tgagaaaatt catgatctgg
    14641 atggtatatt tgtcggtctg cataatctgg ccggtctcta taaatgtaag attcaggttt
    14701 cccggatcat ggtaaacggc accaccaccg gaaaacctgc gtgctatctt gatttgttgg
    14761 tcttgtacga atttgagatt tacctcggcc catacatcct gatgcttacc gatcacgatt
    14821 gatggttcat tctgccaaag catgaaaata ttctctttga aattcttgag cagatactct
    14881 tcggcggcca aattgaagta tggatccgtt tgtgtattgt gaatgcaaag catcaggaaa
    14941 ctgttttagt taggcgtttt attagatata taaactttcg tggaggatct cactgactgt
    15001 cggatgcggg aaaatatttt tcttaaattc atcgactgta taaccattct cgacagcgat
    15061 tccggcggtg acgataatct cggatgccgg attccctagt agatggcaac cgatgatacg
    15121 atcctcgtcg tccgtgatca gtttacataa accattacca ttctcgttct ctgcgacgaa
    15181 acgtccggaa taggtcatcg ggatcttttg aacacggaaa ctttccccat tcgctaccaa
    15241 ttcctcttct gtcttaccca cgctcgccaa ttccggattc gtataaacta ccgccggaat
    15301 ggctttatag ctcatctcgt ccggtatgcc taggatatgg tgtatggcaa cttccgcttc
    15361 ccggtaagcc gtatgtgcca gcagggaaaa accggtaata tctccagccg catatacatg
    15421 tggatgggaa gtcagcatat gttcgtttac ctttacaccg gccccttgta tttcgatcgc
    15481 tagattttct agtcccagac tctttgtaat cggacggcgg cccacgctca ccaatatttt
    15541 atcggcttca atcgtgtctg ccttgccgtt tttctcaaca aagactttct ctgcggatac
    15601 ctctgtaact ttggtattca agaaaaactc tacgcctttt ttcttatact cggatcgaag
    15661 catcgctgag gtttctttat ccatattccc taatatctcg ggtagcatct cgattacctt
    15721 cacctttacg cccatactgt taaagaatga ggcgaactcc attccgatca cgccaccacc
    15781 gataatcgct aacgattttg gcaaatcgtt gagatcaagg gcttcccggg aagtccaata
    15841 cttgacctca gataatcctt tgataggagg gatcacggtt tcagagcctg tacatactaa
    15901 cacattcttc actaaatact cttttccatc acagtgaatc cgtatatttc caaactcctc
    15961 tccggtgatt cgtgcctctc cttctacgat ggtgacgccg ttacccgtaa gccgggcttt
    16021 taccccgagc gtaagtttac ggacggtctt gttcttccgg tcgataatct ttgccaagtc
    16081 gaaacttggg tctttcatcg ccactatacc atatttggag gcacttttga tactgtctag
    16141 tatcttggcg gagtataaaa gagtttttgt cgggatacat ccctcgttta ggcagacgcc
    16201 accgatagcg ttcttctcga aaaggatcgt ttttaatcca ttctccgaag ccctttcggc
    16261 ggcggtgtaa cccgcaggtc caccgcctat gattgctatg tcatattcca tatacattaa
    16321 ttataattat ttgaatacta aaattcgttc ctctaatggg gcgaattgtt tttctcccgg
    16381 ttcttgcgta gaggtaccga acggcatctc ggcgatcagt ttccagttcg gattgatatg
    16441 ccattgttta gcgaccgcct cgtcgatcaa cgggttgtaa tgttgcagag aagcgccgaa
    16501 accggcgtct tccagcatag tccatatcgc gagttgatgc atagccgatg tctgttggga
    16561 ccataccggg aaattatctt tataagaagg gaattgcttc tgcaagcctt ctactaccgc
    16621 cgtatcctcg aaaaagagga ccgtgccata gccagcctcg aaagaattat ctatctttgc
    16681 ctcggtagcc ttataggctt cggcggggac gattttacga agcgtgtctt ttacgatttc
    16741 ccaaagcttc ttgtggcttt cacccagtag cagtacgatt ctcgtagact gcgaattgaa
    16801 tgcggaggga acgtgagtga ccgctgtctt aataatctca tgaatctcgt tgtcggaaat
    16861 gggagagttg ttacctattc cataatgtgt ccggcgatgc tggatcgctt ctttaaaact
    16921 tcttgccata atgaatatca tgttatgttg ttatatacct ataactaatt taagacatga
    16981 tttgttgagg aaaaaatatt tgagaattct tgcggataaa tcaaaataat tcttaccttt
    17041 gcaccctgta aagataagac tctattagaa tcttcgtttt tgttcatgat gctagttcag
    17101 aaagggaaga cacatagcag gagttgactt aaatttcgta taatttaaaa gaacagatta
    17161 gaaatgtcta aaatttgtca aattactgga aagagagcaa tggttggaaa caacgtttct
    17221 cactcaaaga gaagaacgaa acgtaagttc aatgtcaacc tgtttacgaa gaagttctac
    17281 tgggtagagc aggattgctg ggttagcttg aatatatctg cggctggctt acgtacaatc
    17341 aataagttag gtttggatgc ggctatcaag atggcggctg aaaaaggtta tttgaacgca
    17401 taatttgtgg aggatataga aaatggcaaa aaaagcaaaa ggaaatagag tacaggtaat
    17461 ccttgagtgt acagagcaca aggaaagtgg aatgccgggt atgtctcgct atatcactac
    17521 gaagaataga aagaatacta ctcagagatt ggaattgatg aaatacaatc cggttttgaa
    17581 gaagatgacg ttacacaaag aaattaagta ataggagatt ttaaacgatg gcaaaaaaag
    17641 cagttgcaac atttaagaaa ggtgacggtc gtacttattc caaagtgatt aaaatggtta
    17701 agtctccgaa aacaggtgca tacatcttcc aagaagaaat gatccctaac gaagcagtaa
    17761 aagattattt cgctaaataa taaattagcg aattaaaaga atataagagg cttctctccg
    17821 ataaagcgga ggggagcttt ttttatgccc taaacttttg aaagtatagt tggttacaaa
    17881 caaaatattt tcttaatttt gttgggttaa tttgtagaga cagggcatgc cccgtctctt
    17941 cccatccaaa tggtagtttg tatgaaataa taatataaca agataaaata attaaagcta
    18001 tgagattcga tgtatccagc actgcgctat tatcacgttt acagtctata agcaaggtta
    18061 tcgcttccaa gaactcttta ccgattctgg acagcttcct ttttaaccta gaaggaaata
    18121 cgcttacggt gacagcttcc gatgccgaga cccggttggt gacttccgta gacgtcatga
    18181 atgcccaagg tgccggactc tttgcggttt ccgccaagat attgctcgat ccgctgaaag
    18241 agcttcccga acaaccgctt acttttgata tcaatgatga gaatttggag attttcattc
    18301 atttccagaa tggaaagtat aattttatcg gtcagaaagg ggacacatat ccgcagcaga
    18361 agccgttgaa tgataacgct atctctatct cgatggatgc ccagatgctg ttaaacggca
    18421 tcagtcgttc cttgttcgcc acagccgatg atgagcttcg ccctgtaatg aatggtgtct
    18481 atttcgatat ccatacggat gatttgacgt tcgtggcatc agacggacat aaattggttc
    18541 gcttgcgtaa cttggcggtg aaatccccgg aacgggcttc tttcattttg ccgaagaagc
    18601 cggctaattt attgaagaat ttgttggcga aggagtcgga gcaagtattg attaagtttg
    18661 atgataacaa tgcgtatatt acttgcacga acttcgagat ggtttgtcgt ttgatcgagg
    18721 ggcgttaccc gaactataat agtgtgattc ctcaagaaaa cccgtttaag gtaacgatcg
    18781 atcgtatctc tttcttgaat gctttaaagc gtgtttctgt cttttctaat ccggcgagca
    18841 gcttggtgaa gttgcacttg aaggatagct tgattacggt ttccgcccaa gatatcgatt
    18901 tctccacttc tgcggaagag cgtattgttt gtcagtttga cgggacggag ttaagcatcg
    18961 gttttaaggc tacatatctg atcgagatcc ttggaaatat cagctcggaa gaggttgtat
    19021 tagaattagc ggacccttca cgtgccggct tgatcgttcc ttctgagaat gatgaggacg
    19081 aggacttgct catgttgctg atgccgatga tgttgaatga ctaataaata aataatgcag
    19141 ttaaacttaa ggaacccgct ggtctttttt gatttagaga ccacgggtat aaatatcgta
    19201 aaggaccgta tcgtagagat ttcctacgtg aaggtcttcc caaatgggaa agaagaaacg
    19261 aagacacgcc ggataaatcc cggtatgcct attccccccg aatctaccgc tattcatggc
    19321 ataaccgatg aagatgtaaa agattgtccg acctttaagg agatcgctaa atctttggca
    19381 acccagatcg agggttgtga tttggccgga tataattcca accgttttga tatacccatg
    19441 cttgccgagg agtttctgcg tgcgggtgtg gatatcgatt tgaaccggcg caaatttatc
    19501 gatgtacaga cgattttcca taagatggag caacgtacgt tatctgccgc ttataaattc
    19561 tattgcaata aaagcttgga gaacgctcat acggctgagg ctgatacgtt ggctacatat
    19621 gaggtgttga aagcgcagct ggatcgctat ccggatttga agaatgacgt tgctttcctt
    19681 tcccaatatt cctgctactc gaataatgtg gatttcgccg gacgtatggt ttacaacgat
    19741 aaaggcgagg aggttattaa cttcggtaag tataaaggcc gtttggtaac ggagatcttg
    19801 aagtcggatc cgggttatta ttcttggatc atgaatggcg atttcccgtt gaatacgaag
    19861 aaaatgttga cagagatccg tttgagagac tttaattcaa aataaggcga tgaataattt
    19921 tgagttttgc aatcctgtaa aggttgtgtt cggcaaagga agtattgccc gtttgtctgc
    19981 gttacttcca gaaggaagta aggttctggt ggtatacggt ggcggtagca ttaagaaaaa
    20041 tggcatttat gagcaggtga cggcagcttt gaaagacttc catacctatg agtttggtgg
    20101 tattgaggcg aatccccgtt atgagacttg tatgaaggct gttgagttgg tgaaggggga
    20161 gaatatcgat ttcttgctgg cggtaggcgg cggatcagtg atcgacgcta cgaaatttat
    20221 cgcttcggct acgtttttcg agggagatcc ttgggatatc ttgtcgaaag gtggcgtgat
    20281 aaagaaagcg cttcctttag gagtagtgct gactttggcc gctaccggtt cggaaatgaa
    20341 tgaacgggcg gtaatttccc gggaatctgt ccatgagaaa ttaaatttca tgtctccgtt
    20401 ggtgttccct aagttcgcta tcttagatcc gcaggtaact tattctttac ctgagcgaca
    20461 ggtggctaac ggtgtcgttg actcgtttat ccatgtggtc gagcaatacc tgacttatcc
    20521 ggtgaacgct aaggttcaag attattttgc cgagggattg atgaagacaa ttgtggaaga
    20581 aggccgcaag gtcttgcaaa atccgaatga ttatgatatt cgtgctaatt tgatgtgggc
    20641 ggctacgaat gccttgaact gttggatcgg ccaaggagta ccccaagact ggtcctcaca
    20701 ccgtatggga tatgcattga cggcgcagtt cggcttggat catgcccaga ctttggcggt
    20761 tatcttgccg ggtgtcatga cctatatgcg taaggagaaa gcggcgaaac tgatccggat
    20821 gggagaggtc atatttggta ttaccgaagg atctgccgat gaaaaggcgc aaaagtcaat
    20881 agaggctacg gaagattttt tccatttcat gggattaaag acccgtcttt ccgactatgg
    20941 gatcaaggag tccgacttgg atgctttggt ggaacctatc gatcgaatgg gatggaaact
    21001 tggcgaatat ggcaatataa actcaaaagt agccaaagag attcttttgt tgaggttgta
    21061 gagacgcaac gtgctacgtc tctactggca aagataaatt gattcgatat atgatattga
    21121 aagataaaca tattatatta gggattacgg ggagtatagc cgcatacaaa gccgcttata
    21181 tcatccgggg attggtgaaa aaaggagccg aggtacaagt ggttatcacg ccggcgggaa
    21241 aagagtttat cactccgctt acgttatcga cgttgagtag ccaccctgta atcagcgagt
    21301 ttttttccaa tagggatggt acatggaata gtcatgtgga tctggggctt tgggcggatg
    21361 ccatgttgat tgctccggct accgcttcca cgatcggtaa gatggcgaac ggaatcgccg
    21421 ataatatgct gataactact tatctttctt gtaaagcccc tgtattcgtg gctccggcca
    21481 tggatttgga tatgttcgct catccgagta cccaacagaa tctggagcgc ttgcgttcat
    21541 tcggtaaccg gattatcgaa cctgccgagg gggaattggc gagccatttg gttggtaaag
    21601 gccggatgga agaacccgat aagattatcg aggttttgga agacttcttt tccgctcaaa
    21661 aagatcttga aaaaaaaaag atcttaataa cagcaggtcc gacatatgaa aagatagatc
    21721 ccgtacgttt tataggtaat tactcttccg gtaagatggg gttcgcttta gcggaagctt
    21781 gtgcggagag aggggcggag gtgactttgg tcgctggtcc agtctcttta aaaacacatc
    21841 atccagctat taaacgaatc gatgttgagt ctgccgggga aatgtaccaa gcggcgatga
    21901 ccgcattccc gagtagcgat gctgccatat tatgtgccgc tgtcgccgat taccgtccgg
    21961 agaatgcttc cgagcagaag atcaaacggg aaacggagag agagatgacg cttcatttgg
    22021 ttccgaaccc ggatatcgcc gcctctttgg gtgcgatcaa gcgggaagga caggtcatgg
    22081 tggggttcgc cttggagacg aacgacgagg ctactcatgc cgaaggtaaa ctgaagagga
    22141 agaatctcga tttcatcgtc ttgaattctt tacgagacca aggtgccggt ttccgttgcg
    22201 ataccaataa gatcacgatt atcgacaatg ccggaggagt aacgagctat ccgctcaaaa
    22261 cgaagcggga ggtagcctgt gatatcgtaa ataagttggt aacattattg aaatgagaaa
    22321 agtaagaaga ctgttttatc tattcatgct ttgcgccgct cctttttgtg ggaaggcgca
    22381 agagttgaac gcccgtatca cggtgaacgg agacaaaatt gcgaccgcta acaagcaaat
    22441 cttcacgacc ttacagaact ccttgactga gttcgtgaat aaccggaaat ggacggatgc
    22501 cacgtttgcc gtcaatgaga agatcgattg tacgatgacg attatcgtga atgaattgga
    22561 tgagacgaac ttcaagagcg agatccagat acaagcccgc cgtccggtct ataattccag
    22621 ttatacaact actcttctga atttcaggga tcaacagttg gattttgagt atacggaggg
    22681 cgagccgttg gactataact caaatacgct gaccagcaat cttacggcca ctatcgtgtt
    22741 ttacgtctat gtgatcttgg ggcttgattt cgatagtttc gctccgaaag gtggaactac
    22801 ctatatacaa caagcccagc aaatcgtgaa catggcccag tctgagatgt cgtggacggg
    22861 ctggaaagct tttgatagca accagaaccg ccatgccgta gcgacggctt tgcaagataa
    22921 cgcatccgac gctttccggg aaatgtggta cacgtatcac cggaaaggac tcgatgaaat
    22981 ggcagcaaat ccggatcgtg gacgtacgac gatcattagt gcgcttcccg ccttgcagga
    23041 agtaaagaaa gcccggccta cctctgtgct tctacaaatg ttcgccgacg ctaaattaga
    23101 tgagattatc gcaatttatt cgaaagcgac cacacaagag cggcaagagg gctataagat
    23161 gctgttcgag atctatccgg cacaatccac tcgcttggaa gagcttcaaa aaccagtaag
    23221 gtaaaatagt tatgttgaaa tccttattta tacagaactt tgtcttgata gacaatttgg
    23281 atatccgctt tgataaaggc ttctcggtga taacgggtga gaccggagcg ggaaaatcaa
    23341 ttatattagg agccttgtct ttggtgctgg gacagcgtgc ggatggcaag agtataaaga
    23401 aaggttcgga taaatgtgtg atcgaggccg tatttgatgt ctcaaaatat cagttggagc
    23461 ctttcttcct aagtaacgac cttgagtacg acgcggatag ctgtatcttg cgtcgggaac
    23521 tttatgcctc cggcaaatcc cgtgccttcg tcaatgattc tccggtttcc cttacgatct
    23581 taaaagagtt gggaagccgc ttgattgata tccattcgca gcatcagaac ctattgttgg
    23641 gcgacaaccg tttccagctg aaagtgatcg atgtaatggc cgaaaatgag atcttgctca
    23701 ttctttataa gaaggaattt actcgttatc aggcgttgcg aagggaactg aaagatttga
    23761 gggacaaagc ggctcaaagc aagcaggagg aggactatat ccgttttcaa ttggaacaat
    23821 tggacgaagc caaccttcaa ccggatgagc aggatgagtt ggagcaagag caagaaactc
    23881 tctcgcatgc ggaggagatc aaaagctctt tatataaggt aaccgaactc ttggacggcg
    23941 aggagcaagg agccatccaa atactcaagg aagccctttc caccgtggat tccttagaaa
    24001 gatatttccc gaaagccaag gagatctccg agcgaatccg ctcggcttat atcgacttga
    24061 atgatctggc ttccgagaca gacgttttaa aggaagatgt agagttcaac ccggaacgat
    24121 tggaatgggt gaatgaacgc ttgaatatcc tttatacact tctgcaaaaa caccgtgtct
    24181 ccaccgtgga tgaattgatt gctatacggg atcaatacca agagcaattg cgtgcgatcg
    24241 attctttcga tgagcaaatc ggtttgttag agagtcaatt ggatgcctcg tataaagagt
    24301 tgcttcaaca agcctccgtg cttagcgagc agcgtaaagt cgcttccacg gcgatggcct
    24361 cgcaattggt caagatgatt attccgttgg ggatgccgaa tacccgtttc cgtgtggaca
    24421 tccttcctcg caaagagccg gagagcgatg gaatggacga tatccgattt atgttctccg
    24481 ccaataagag cgcggaattg cagccggtag cccaaaccgc ttccggaggt gagatctccc
    24541 ggttgatgct ctgcattaag gctatgattg ccgggttcac cgctttacct actattatct
    24601 ttgatgaggt agatacgggg gtatcgggtg atatcgccga taaaatgggg gatatcatgc
    24661 aagaactcgg aacaaagatg caagttttcg ctatcactca cttacctcag atagcggcga
    24721 aggggcaagc tcattatttt gtttataaga aggataccaa agaccgtacg ctgacccgta
    24781 tcaagcaatt agagggggag gaacgtgtga acgaggtggc ccgtatgttg agcggagcct
    24841 cgttgacaga ggcttctctt gccaatgcga aagatttgtt gggtatcaag gattaaacct
    24901 ttctgaagta gggcagtctt agataaaaga acaaacgatt cgctttatta ttaacttaaa
    24961 attgaaaaga catgaaacga ttcagcttac tatgtgtgtt ggctatattg tgcagtttac
    25021 ccgcttacag ccagttttgg atcagttttg ggtggaatga accgcattgt caaaattgtc
    25081 tttggatgga gcaagcgatg catttgcccg ctcgccaagc agcggaatac cataagatta
    25141 tccataagta cggacagaaa atagagaagg aggcccgccg tgactatcgg tattgggacc
    25201 gtgcggctcg ccgtatttac gatttgcgta tggaaaggga tcgtaagatc caacgtctat
    25261 tgactccggc ccagttcaat ctatatgtcc gttttgtaag ggagcatccg caacgtatcc
    25321 atgattatcg gggatggtat gcgaatccga gatatccgga tcgccgcccg tcccatgact
    25381 gccgtcgata tgaggataac tattggaatt accgctgggg taccattcac catgacaatc
    25441 attggagaga cgaccggcat gactcagata gacattggga tcgtgacaac catcgtcatg
    25501 actatcggaa accagcgaaa ccggataagc ccaaacctaa aaagaataag aaggatcggg
    25561 acgatagaaa agaacggtat tatagcaatg ggcgaaaggt ctaataattc aaccatagct
    25621 tgaaagaggc ccatttttct ttgctgacca atattttctc tttatgttcc ggctttatgt
    25681 ggacaatgac cttattctga aaatagggct ctattttcac gatggattcg atatttatga
    25741 tcgtctgccg gttcgtccgg aaaaatttat cgggatctaa ttgttccatg agtttatcca
    25801 gcgggaaatc gattatgtac tccttgtttt ggcgtgtgac agcgaaggtg atcttgttta
    25861 atgaataaaa gtggggatat cctccacctg taaagtgatc agtttctcgt tgccggaaat
    25921 aaggaaacgg gtcctgtatt tcttgccggg atacgtgagg gaatggagta cttccaataa
    25981 atcattttgc tctaagagct tctggttgta cttagacgtg acatgctcga atttttggat
    26041 ggcttcctcc aatctctctt gtcgtatcgg tttgagtaga taatcaatac tgtttaccgt
    26101 aaaggcccgg actgcatatt catcgtaagc ggtcgtaaag ataatgagac ttgtaggaca
    26161 agcctgttct ataaataaaa aagaatttcc atccgacaac tggatatcca gaaaaacgat
    26221 atccggatgc ggatgggaag cgaaccaagc cacggatgat tcgatgcttc cgggtatctt
    26281 gatgatatcc cattgcgggc gtaatttctt tatcatacct tccagtaacc gggcggccgg
    26341 tttctcatct tcgataatgg ctacttggat attattcata aataagtggg attgatacgg
    26401 tgaattggtg atcatttttt cggatctgga tatcctgctt acatagtaat tgataacgct
    26461 ccgacaaatt ctttaatcct ttaccggatg cgtttgagac ttttttaggc cgtaatgtat
    26521 tgctgacgca tagatatcga ctgttccttt cagtatatac ccgtatggtc atcgggttaa
    26581 aatcgtcgat ataattatgt ttcacgacat tctcggctag tagttgcagt gtcagagggg
    26641 gcaattgatg gtcaatgacg ttgtcgggaa gatcgcgttc caacgacaaa caatctccca
    26701 gccggacttg atggaggaat atataggaat ccagaaaatc aagctcctct tttaaagaga
    26761 cgatctggca ctgttgctgg cggagcacgt aacggtatac ctcggataga tgctgcgtaa
    26821 acttgaccgc cgtagccgga tcatactcta tctctgctat caatgtattc aagctattga
    26881 ataggaaatg aggatttagc tggctttgga gagcggtata tttagcttgt atagattctg
    26941 cttccaatct ttgtttctcc ttatataaat tcaatgtata acgcatcgaa taattaatca
    27001 agagaaggct gaaaatgatc atctccacga accagacggc tattaccaaa ccggcccctt
    27061 ttgcccggat cacgaaagga tcgccaatgc ttgtgatcca tttcaacgag ataaacaggg
    27121 tacaattcat aagtagcaat aggatcgcta ccagcagata atgccataac atccggcttt
    27181 tatcgatata atataatgga tagttggtag ccatccaatg gctgctgacc agtaaactga
    27241 aaccgaacaa gttgaatacc gctatcgtga tggacaaagc gatcaatgag atctttatat
    27301 cggggatgcg ctcttgtagc tccgtatgat ataacagcaa gaaataggaa aagaccccta
    27361 atgccgaaaa caaaaggata catgccgatt tcccgtatga tatttctttc atgacctatt
    27421 ctttttcgcg aagataataa attgcccgtt cgaaatccgt cttcgccatc tgtgcgttta
    27481 gtttggattg tatataatta acctgagctt gctgatgata taattgagcg ttgataacct
    27541 cgacgatgga aacattcccc tccttataac gctccatggc catttgctca ctttcggatg
    27601 cttttgataa tgagctctcg gttagttcga ctttatcgat agcttgttta tagttgtaat
    27661 gggcggtttg tatttccagc cggatcttat cttgcgtctt gctgagattc tgttgagcca
    27721 tattgatggc gtacgaggaa gcgttgcggg tactcttacg ttttccccat tcgaagagcg
    27781 ggatactgag cttggcgtag atcgcatagt tcggatctag gtcggatttg aagttatagc
    27841 ccggtgagga ataacttcca tctactccaa tatggaattg gggtaagaaa tgggcatccg
    27901 ctattttccg ggatgattcc tgtaactcga tcttgttttt ggcgatccgg tattccggcc
    27961 tgctggttat cgcgttatct atctcatccg ataaagggat aaattgtttg agggcgatta
    28021 cggaatgatc gatcggcaag gtatcgctcg ggtttacacc agcgaaagaa ttaagggcca
    28081 aacgtgcgat ctcggcgtta tcacgagttt gcaataactg gaaatctgca tcgtttagct
    28141 ttacctccgc cataagaaga tcgtttcgat cgatgtattc gacttctacc cggtggcgta
    28201 cgacgtccac cagttgctgt atggatgtac gaaatgcctg tgccacgaaa accagctcgt
    28261 gctgggctac cgcattccaa tagtagatat cggcgtcgtg tagggtattg ctttttatac
    28321 gatcggattc attggatgcc aactcttttt cttgccgtgc tttttggtag ttggcacgaa
    28381 tgccgcctcc ggtataaatc ggttgcgaga gggagagagt cgccccatat ttcagatctt
    28441 taccttgaaa ataaaggggg gaattcatag atggcaaatc aatcgataat tctagcggat
    28501 taccggtata attgaaatta ccttccgccg agagtttcgg tttgaaatcc gcacgggccg
    28561 atttgatcat ttcctgtttc atggcctcgt tgtatcccgc tgctttcaag tcttggttgt
    28621 attccaagac tttttcccta tattgcgctt gataatcgct gttttgtgcg attaacggga
    28681 aggataggaa ggataagaga ccgctgataa tatatacttt gtccattttt atcgtttatt
    28741 tgtgaggtga atgaatccgg taaaacaatg cgtataacgt cggggttacg aataacgtaa
    28801 gtaaggtggc gaaggtgagt ccgaagataa tagtcgccgc cattccaccg aacgctacgt
    28861 cgaaaagtaa aggcaccatt cctaaaatag tcgtggtagc cgccatcaag accgggcgag
    28921 tccttgagat ggttgcctct atgatcgagt cgtatggaga gataccgtta cgacgttgcg
    28981 tgttaatctc gtctaataat acgattacgt ttttgataat catacccaag agccccaacc
    29041 atccggcgat cgggaaaaag ccgaaatcga acccggtaag taacataccg atcgctaccc
    29101 cgattaagga gagagggagc acgcaaagga tgattatcgg ttgacggaaa ttggagaata
    29161 aagcgaccaa tataacaacc aacatcaaga aagccagcgg gaagaatttg acaagggctt
    29221 gcaatccctc tgtctggtct ttatattgtg aatcccagaa gaagctatat ccttggggca
    29281 ggttcatttt ctcgatctct tcccgaatct caccgtgtac ctcagacatg gtgtaaccgt
    29341 ttttcacgcc acacatcgct gccatagaca attgccggtt gtaggtcttg atctgcggat
    29401 attcccatgc ggaggttacc tgtcgggtta cttgtgacaa gggtgcggat ttctctccgt
    29461 tccacaccga gaaatcacct aatgaacggg gatcgtcgat tccgctcttc tccgatttca
    29521 ataagaccgg gactttcttt tcctcatccc ggtaaatccc gataaccgta ccttcctcga
    29581 tggatttgac ggattccatc aaattagcct tggtgatacc taagaaaccg gcttttaccg
    29641 gatcatatac cgggcgtatc atataggtca tattacccca ttcattccgg gcatcggtta
    29701 ctttcgggtt ccttcgcata atgtcgatag ctactccggt caaagagtcc aataccgccg
    29761 ggtccggtcc gaggaaacgg gcttctatca aggcttccgt aagcgggctt aactcaaact
    29821 tgttcacatt gatgagcggt tccggatatt ttaagcgaat tgagtcttgt agcaaggcat
    29881 gcaattcccg ggcctctccg gatgtcttgc attttaccaa taattgggca tagtttggtt
    29941 ggggaccgaa gctaacgttc gatagataat aacggggcgg tgtccgtccg atataagagg
    30001 aaaccatttc cgtctgcgaa tattcttgga tggattcggc catatcggta gcgtatcgat
    30061 cggtttcctc gatggctgta ccttccggta gccacatatc taaagtgaaa tactgcttat
    30121 cgagcgaagg cacgaacact ttcgggataa actggaaact ccatgcggag ataaccaata
    30181 gaacggataa gctacctact gtagcgtatc ggtatttgat gacaaggcgt agggaagacc
    30241 gaaaataatc atagtatttt ccagagaata attcccctgt taactcgtcc ggtctggggc
    30301 gccgtacaaa ctcttggatg aagaatgggg tttgcgtaag tgcgaacacc cagctgaaca
    30361 tcaaggatac tccgatcacg atcactaagg atgaaagtaa ttcgcccgtg atatgcggtg
    30421 aatagtaaat gggcaagaac gtgaggatcg cgatagccgt agccgccagt agaggcaggg
    30481 cggtggatga gcaagccctc atgattgcga tacgtttgcg catgcctcgt tgcatattta
    30541 ccaaggcaga gtccgatact acgatggcgt tatctaccaa catacccatc gcaatgatga
    30601 tagcggcaag agacattcgt tgcaaagcga tcccgttggc gaacatgaca attaaagtgg
    30661 cgaagataga gaaaaccaat ccgctaccga tcaaaaggcc gtttttgaaa ccgataaaga
    30721 acaataagat cgctactacg gtcacgacgg agatgatcaa gttcaagata aatccttggt
    30781 tggccacggc ggactcatat ccttggtcgt atatggaggt gagctcaaaa cccttgggca
    30841 tggtctccga aaatgattga atacgctttt tcacggcctt ggccatatcg accacgttcc
    30901 cggtcggtac ggtagagata gcgataccga ccgcttgctt gttattgatg cgcatgaagt
    30961 tttggggcgg agtctggtaa ctctcctcaa tacgggcgat atcgcctagc cggaaatgtt
    31021 cgccggaatg agatacgatc gtaaggttac ggatatcatc caatgagtaa aaattaccgg
    31081 tggattcgat acgtatgcga gtctccccgt tgcgaatact cccggcgtct accattttat
    31141 tctgtccgtc gaacgcccgt ttgatatcag ctgtcgtaat accccgattg gataagatcg
    31201 tggggtttat ccggatatcg attacgggag tttgtatgcc gtagatctct acctttgcca
    31261 cgtcttttac tttcagtaaa tcatctttga tcagtttggc ttgatcctcc agttcccggt
    31321 aggtataaga ttctccggtc aatccgtaga aaacacccaa tacatcgcca aaatcatcat
    31381 tgacgatgga ggttcccgct ccggaaggta atttgccttg tacgtcgttt acctttcggc
    31441 gtagtttgtc ccataactgc tgcatctcgt cggcccggat ttcctttttc acgtagaccg
    31501 tgatcttgga aagtccagcc cggttctctg tcttcagata gtataactcg cctaaggatt
    31561 gaatggcttc ttccagtaca tccgtcactt ggaactgaac ttccgagggg gaggcgccgg
    31621 gataaggggt aagtaccaag gcttgcttga tcgtaaacgg ggcatctccc agttttccca
    31681 tctttgcgta agagaacagc ccccctgcca agattaggac tagcaggagc catgtaaccg
    31741 ctttgttttt caggaaatat ttgatgaatt tttgcatctt acttattttt ggatggttac
    31801 ggtactattt tcggaaagga aacgttgcct tgtcaatacg acaaggtcat ttcccgtgat
    31861 tccttccacg atctctatct ggttatttct ttgctcaccg agtttgacgg gaacggagtt
    31921 taccttgtct cctttaacca cccatacata atctcctttt tgggggcggt gacagatagc
    31981 cgttaaggga agccataaat tttgagaccg ctcttctttg ggtaggtcga tcgagaggat
    32041 tccactcatt ccacccagcc attccatatc tggatttggg acaatggcgg tcagcagata
    32101 agagaggtta ttgtttgtcg tacttttaga cacatataaa tcggaagggg tgattgtccg
    32161 ttcgggagcc gtatcgaaat ggatttctat ttgacatagc ttctgttttt ctttatcata
    32221 taagtgtaag gcgacttcct ctggtatata ggtctcgatc ttgagcctgt ccagttctat
    32281 gaaggtaagg atcggctcgg tcgctttcac gtcttggaaa ggttcgatat ggatattttg
    32341 gatatatccg tcgtaagggg cggacagatg gtgtcgctta aggcgttgac ggcggtctcg
    32401 taattggatt tggcgacaag gaaatccgct ttcgctcttt cgtagttact tccggagatg
    32461 ttattctttt tgtaaagggc ctcgatccgt ttatactctt ggttggtttg cgagtagagc
    32521 gcctctgttt gctgcttgcg aatcaagaag tcacggttat cgatcaagag gattgtgctg
    32581 cctttggaga acgcttgtcc gggccgtaag tcgaaattca agacggggcc attgatgcgg
    32641 aaagagagga ctgtctcatt atagggtctt gatagaaagg tgtattcacg acttctgccg
    32701 gtctctgtct tttttattgg agagatcacc tcgacaggta agttcgtgcc tttggacttt
    32761 gtgttctttt ggcatgccga taaaaggatg cccagaagca ggatatatga aattcttctc
    32821 ataagatata cctagttatt tattaccggg caaaaataga ggcaatgggt gaaggaataa
    32881 ggcggatttt tactgaaccg gaagataccg tcgctcaact ggaaaataga ccggcccaac
    32941 tttaatttat aacgaggcgt gcgatcgatg ccttacaccg atggattgta gtcgtaatat
    33001 ttactgcaac ctgcctcgcg gcattactgc aacacgtctt gcagttttac tgcaacccac
    33061 gtgcagtgac actgcaagcc ttgtgcagta gtactgcaac ccgggttgca gtgaaagaca
    33121 aaccggggat ggggtgaata agcttccatg gttccgcttt ttttatgtac ttttgcggac
    33181 aaaaagagaa agtgatgaca ttgccttcag aagaacatat attccagtat ccgggacaag
    33241 ggcggatcga ggtgatttgc ggttccatgt tttccggtaa gacggaggag cttatccgcc
    33301 gtttgaagcg ggctgaattc gccaagcagc gggtggagat tttcaagcct gcgatcgata
    33361 cccgctattc gcaggataac gtagtctcgc acgatagtaa ttcgattcct tctactccgg
    33421 tggattcttc ctccagtatc ctattgttca cttccgagat cgatgtggtg gggatagacg
    33481 aggcccagtt tttcgacgag ggattggtaa acgtatgcaa tcaattggcc gctaacggta
    33541 tccgggtgat cgtggccggg ttggacatgg actataaggg agttcctttc ggtcctatgc
    33601 cggagttatg cgctatcgcc gatgaggtga cgaaagtgca tgccatctgc gtgaaatgcg
    33661 gacgtttggc ttacgtatcc catcgtatcg tgagaaatga taaacgggtc tttttagggg
    33721 aacaatccga atacgagcct ttatgccggg aatgttatgc gaaggctgaa ggtttgaaga
    33781 attgattatt tatccctaca tttgtgaaat taatagtttt gcgttatata aagtatgaaa
    33841 gaaaacgaaa tggtgttcgg cattcgtgcc gtgattgagg ctatacaggc tgataaggag
    33901 gtagataaga tccttgtgaa aagggattta caaggggatc tatccaaaga gttatttgag
    33961 gtactgagag gccgtgagat accggtacaa cgtgttccgg ctgaacgctt ggatcgtttg
    34021 actcgaaaga atcatcaggg ggtgatcgct tttatgtcgg cggttaccta ccagagcttg
    34081 gaagatatca ttccttttgt gtatgagcaa ggaaaagatc ctttcatcgt attgctggat
    34141 ggggttacgg acgtgcgtaa tttcggcgct attgcccgta cctgcgagtg tgcgggagtc
    34201 gatacgatcg tgattccggc aaaaggaagc gtttcggtaa acgccgacgc gatcaagacc
    34261 tctgccggtg ccttgcatgt attgccggtt tgtaaggaga agagtatcaa ccaagcgatc
    34321 cgtttcttgc agcaaagcgg ggtgaaggta tttgccgcca gcgagaaagc ggcggagaat
    34381 tatacggcgg tgaagtatga aggaccggta gcgatcgtga tgggagcgga ggatacgggt
    34441 gtgtctccgg agaacttgcg catctgcgat aatatggtaa agattccgca attcggaacg
    34501 atcggctcct tgaatgtatc tgtagccact tccattctgg tgtacgaggt ggttcgccaa
    34561 cgtatgaacg agcaacaata ataatctgta tataaactaa agaagaaaat gaagaaagtt
    34621 atcgctacaa aaaacgctcc cgccgctatc ggtccgtata gccaagcggt gcaagtaggt
    34681 aatatgctgt tcgcttccgg acaactgggt atcgatcctg ctacgggact tttcgttgag
    34741 ggatccgtaa aggaacaaac cgcccaagcg ttcaagaatg ttcacgctat cttggcagag
    34801 gcaggttata gcatcaatga tgtcgtaaaa acaaccgtat ttttagcgga tatgggcgac
    34861 ttcgccgtta tgaacgaggt atacgcctct cagttcgaag gtgcgtttcc cgcacgttcg
    34921 gcggtagccg ttaagacact gccgaagaat ggtttggtag agatcgaggt gatcgccgtg
    34981 aaagaataat cataaggaat aacgagagta gtctcatcgc ttgtcgagac tactctcgtt
    35041 atccatcaag actactcccg tgatacgatg cgactactct cgtaattcat cgatacagct
    35101 aatctcaaaa gcctattatc ttctttttct gggagcggga ttcatgtcac ccctctgtcc
    35161 gaataatttc tcaatcaaat cctttcgtcc catcttttgc aatacttgca tgatctgacg
    35221 gcgtgactcg ggtttatacc agaagaagaa ctggcgttgt gccaactttt gttcttttga
    35281 gcgggccgta tatactttct ccaacgtata aggatgatat ccggtataat acatctccgt
    35341 agccaatgtc atcggcgtag gcgtgaagtc ttgtacttgc tccaactgga aatgcaagct
    35401 cttggtgatc accgccagct ccgccatatc cgcctcggta catcccggat ggctggaaat
    35461 gaaatagggg atgagttgct ggttcaaccc gtattgccgg tttaccttat cgaatatctt
    35521 cttgaactgt ccgaattgcg agaaagacgg tttacgcatt tgtttcaaca cctcgtcttg
    35581 cgtatgctcc ggggccactt tcaaacggcc ggatacgtgg cgggcgatta attcctcggt
    35641 ataggtttga gctgccttgt ttaaagattc atccgcataa cggtgcaata acaggtcata
    35701 gcgtacaccg cttccgataa acgacttctt gatctcggga agtctatcta ccgctttgta
    35761 gatatccagt agcggcgtat ggtccgcgtt caagttcttg caaacgacgg gggagataca
    35821 agacggtttc ttgcatttgg cgcaaattcg ctcatctttc cccttcatac ggtacatatt
    35881 ggcggaaggg cctcccaaat cgcttagata tcctttgaaa tcgggcattt cggtaatcgc
    35941 tttcacttcc ttcaagatcg attccttgct tcgggaggcg atgaacttcc cttgatgcgc
    36001 cgatatggta cagaacgcgc atcctccgaa acaaccccgg tggatattca ccgagaactt
    36061 gatcatctcg aaagccggta tcactttccc tttgtatttg ggatgcggca agcgggtata
    36121 gggaaggtcg taggaagcat ctatctccgc ttccgtcatt ggagggaagg gaggattcac
    36181 tacgatcacc tgttttccta ccttttgcaa gatacgtgag gcattgtatt tgttggattc
    36241 ctcttctata taccggaaat tcttcgcttg tttcaattta tcttttaggc attcctcatg
    36301 tgagaagagc acgatatcgt cgtctttcgc atcctctttg tctgccagat aaaccgtttg
    36361 gcggatgttc ttgatctcgt tgaaaggaat gccggacttt aggcggcgca ccaattcctt
    36421 gatcggcttc tcgcccatgc cgtaaatcaa taaatcggcc gggctactgg caaggattcc
    36481 cggtaatagc ttatcttgcc aataatcgta atgcgtaagc cggcgtaatg aggcctcgat
    36541 gctacccaat acgacgggga catccggata caattctttc agtattttag tatagacgat
    36601 gctcggatag tccggacgca ttcccggacg ttggtccggc gtataggcgt cgtcgctgcg
    36661 taatcgctta ttggcagtat aatggttgat cattgaatcc atggcaccgg cggatacacc
    36721 gaagaaaagc cggggaacgc cgagcttctt gaaatcccgg taatctcccc gccaatccgg
    36781 ttgcggtacg atcgctaccc gtaatccttc cgcttccaat acacgaccga tcacggccgc
    36841 cccgaaagag gggtgatcca cataggcgtc tcccgagaaa aggatcacgt cgaggtaacc
    36901 ccatccccgt gcctcgactt ctttcttcgt cgtgggcaac caattgtcta gtttaaatgt
    36961 tttcataata caaaggtacg tgataatctt ggaataatca tagagacgct attcataact
    37021 tttatttatg ggggattcgt ttttatgatt aggacaagag ttctcaatct cgtatctttg
    37081 tgtcgaaaag aaaaataaac atttaaaaac aaggtttctt atgaaaacac tcacagacga
    37141 gaagctgacg attgtcggcg cagcaggtat gatcggttct aatatggcac agaccgctat
    37201 tatgatggga ctaacttcta acatttgttt gtacgaccct tacgcaccgg gtttggaggg
    37261 agtcgccgag gaattattcc attgtggttt cgagggtgta aacatcactt ttacctcaga
    37321 catcaaggag gctttgacgg gcgctaaata tatcgttaac tccggtggtg ccgcaagaaa
    37381 ggcaggtatg acccgtgagg atctcctaaa aggaaacgcc gctatcgccg aggagttcgg
    37441 caagaacgta aaggcttatt gcccggacgt aaagcatatc gtggttattt ttaacccggc
    37501 ggatattacc ggtttgatta ccttattgta ttccggcttg aaaccttctc aggttacgac
    37561 gttggccgca ttggattcaa ctcgtttacg cagtgagttg gcaaaacatt tcggtatctc
    37621 tatggatcag gttgagaatt gtcgtacgta tggcggtcat ggcgagcaaa tggctgtttt
    37681 cgcctctacc gctaaggtgg atggcaagcc tttgacggaa cttatcggta cggatgcctt
    37741 gacgaaagat caatgggcgg agatacaaac caaggttacg aagggtggcg ctaacattat
    37801 cgctttgcgg ggccgttctt ccttccaaag cccgtcatat gtatctatcg agatgatcgc
    37861 agctgcgatg ggtggtaaac cgttccgttg gccggctggc gcttatgtat caaacggtaa
    37921 gttcgatcat atcatgatgg cttgggagac ctcaattacg aaagacggcg tagcgttgaa
    37981 agaggtgcac ggtacaccgg aagaagaggc tgccttggag aagagctaca agcacctttg
    38041 cgctttacgt gacgaggtga tcgctatggg cgtgcttccc gctatttccg aatggcataa
    38101 attgaatccg aatatcaaat gatcgaataa caagtcattt agattttcac ggatatatga
    38161 aatccccgct tagatggctt cgtgccggaa agcggggatt cttgttttat tttatcttta
    38221 gtccggggat caggggcgtg ctatctacca gctccaactc ttgcaccatc tgtaatgttc
    38281 cttgtttgta tttctggaaa tggggcgttt ggatatggct tttataagcg tcttgatccg
    38341 cgtaaatctc taggatggtt actttatttg gatgttcttt ctccgatacg gcatacagtg
    38401 taagaacacc cggctctaga cgcatggaag cctcgatctc ttcttccaga aaggcgttat
    38461 aacgctccaa ctgggcggga tcgaccgtga tcttggatag gcggactaag ttcttctttg
    38521 gggcgggctg agaggattcc ttaatgattt tcaacgcttt gatagcggaa gggaagccga
    38581 tataaggaag acattgtata accgccgccg ttaaggtctc cttgctattg ccggccagta
    38641 agttcccttc gagatgcgag tgtagttggc tttcggcttc aagggtcgtt agtatgcaat
    38701 aagccagtaa ctcccgggtt ttcaggtcta gcccgttgcg agtatagata tctccgaagc
    38761 agaattcggt gaggaatcgc tctacttccg gacccatatt tcccgagacg ttcctcatgg
    38821 cctctttgat tccctcgccg taaagtcggc tttgtatggc ttgtcctttc tcgtggcgat
    38881 cttcttccgt aacggtagct tgtctctcca gaggcaaagc gatgccttgt tgcttaaaga
    38941 cttcgttgat ggtatttaag gcattcaatg tcttcggaaa accgatgaac ggagcgcata
    39001 gatatatcgc ctcccgtagc tcgatgggag tgacgcctac gtttagcgcc gctttggcgt
    39061 gggcgttcag ttggggcaag gtttgcatcg tggctaatac ggtgcaagtg ataagctccc
    39121 gggtcttttt atcaagatct cctgtgcgga atacctcccc gaagatgaat ttctggagaa
    39181 tgtccatcat ttccggatct gttccttgtc cggtcaatgc ctcgcctccg aatagctcgg
    39241 tgtaattctt tttacagcgt tcgattctgt ccatattttg ttctgtttta gaagttggga
    39301 tatcttgtgc gaaggctggt atgaagccta gcaggaagag tgcgattgct tttgttttca
    39361 taaggatatc attattgttt aacattacaa agatattcgg atttatctca ggcgcatgta
    39421 tacatattac ggatctttgt atcaaaatta ccgttcgtaa acggagctga tccggatgac
    39481 agccggggtt gagcaaacga ataaagcgcc tgcgattccc ttgcgggaga cacagacgct
    39541 ttcgttcaaa taaatattct tataaagtac gatccggata taaggctttc caccattccg
    39601 gctcgtcttt cagccatttg gcgaaccatg cgtagatggt attttgccag cctatacgtt
    39661 tctgatagcc tacgatacca tgattctcgc catccacctg cacgaattcc acggttttcc
    39721 ctagtatctt caaggcggcg aacatttgga tactttcccc gatgggtacg ttcgtatcgg
    39781 cgttgccgtg aagcaacagg agcggggtct tgatcttatc ggcgttgaac aacgggcttt
    39841 gcttggtaaa gaactccggg gcgttccaag gataagtgcc ggcattcgct acggagcaat
    39901 agccatatcc ccaataacct tctccccaat agctactcaa cgcgctaata ccggcatggc
    39961 tgatagcggc ggcgaaaatg tccgtacggg tttgtaggta ttgtgtcatg aatccgccgt
    40021 agctggcacc gatgcaaccg attttcttct cgttcacgaa cgaatgctcc ttacagaaca
    40081 gcttggtacc ttggatgatc tcatcggcgg tcttcaggcc ccatgcgttt acgtggcggg
    40141 cggcgaattc ctgtccgaaa cctgtcgttc cgctagggtt taaggtgtag accacgtatc
    40201 cgagggcggc gtacatatgc atggaataac gcatctccag cgcacggttc gtcggggaag
    40261 taccgccata gtaataaacg atcatcggat atttcttatt cggatcgaaa tgaggcggta
    40321 ggtaataacg accttggatc gtcgtaccgt catccgactt gaagttccag tcgtgtacct
    40381 cgcctaaggc gatatctttt aatttatctt gcgagagatc atacaccaag cggttctttc
    40441 cacctttcag gtcgtaagcg taaaggcggt tggcgttgga cgcgctctgt ccgtaataga
    40501 agagaaccgg agcgttgtcg gccaacgcat acgacatgat aatatcctcg gaggcggcta
    40561 cttgcttgat cttcccgttt gccgggtcgc acgtataaat ccgttggtaa tcctcatcct
    40621 cacagaggat atagatttgc ccgttgaagc ggttccatac ggcatcgatc acgttcggat
    40681 tgaaatcctt ggtgagaggg gaggctttac ggcttgccag atcgtatagg aataactgcc
    40741 cgtcgtacga gttggagatc tgtccttgct tgatatttcg tccgattccg tcgaaagcgt
    40801 cgcctgcccc agctaccaat aactgtttac cgtcgggcga gaaggcggct tggtttacgt
    40861 acggggcttt ctcccagatc gtatcgatcg ccatggtctg caaatccaat ttataaaggg
    40921 agttgcggga gtgcggcaag gaggtgtaca cccggtcgct ggtgctgaac aatagatagc
    40981 ggctatcagc gctgatatca ttgatataag tgtccgtatg cccgaaagta agttgctcgt
    41041 acaaacctgt ttttaagtca taccgccaga taaaggagcg gtcacggaaa cccgggatac
    41101 ggtctgccgg ctctaataca cggatcaagt ccgtcccttc cttgggacct tcctcttcta
    41161 cggtatagag aagcgtggac tcatcggggg tgaatacgaa ccgccctttc ggaaggttcg
    41221 ggactaatac cgtttgttgg taggtagacg gatctacggt taccaactcc gtaccgtcca
    41281 gaccggtgcg ggtgtaatac aatcgattgc ttttaggcat ccatttggcg gttgtcaaga
    41341 aacctccgtc ttgcaataag acccgtcccg tagcggcatc catcaattgc ccgtacgatt
    41401 cgctcttgcc ctccgggtat cgattgacgt attttaccaa ggcatacttc ccgttcgggg
    41461 agacacttac gccttggaaa tcctttcctt ctaggatatt cagaagggtg tagcgtttct
    41521 ccgggttcaa ggaagctacg actttcgctt ccgcctcgct cttgaaggta gcctttaggc
    41581 tgggaggaca agtgtctgtt tccgctgtca ggtatttaac gactacttga tagcggcggg
    41641 gttccatcac caactcggaa gaggctccga ctggtttatc attgacgaat acttcgaacg
    41701 ccccgggacc cgatatatcg agcgtgcctt ttacgtaccg gtcgctgttc aagaagaaag
    41761 agaatagatg caaggcatat cccttttgcg gggcggcgaa ggtgatcgcg cctgccgtgt
    41821 cagcgtcgag taccgtggcg ttcgcaagcg tttgctcgaa cggtaaggtc gcttttaata
    41881 gattcttcgc ctcgaaaggc ttgccgttta cgttgaggct gtccgctagg atcggcttgt
    41941 tgaccgtgaa cgggcctgcg tgctggaatt gcgttacttt cacgtcttcc atggcgtaaa
    42001 gcgaaagggc ggaaagaagc aatgccggaa ttaagttagt ttttctgttc atatataatt
    42061 agtttaggat aaacgttttc cgcaaacgat gtaaagctgt tcggtatcct ctacgacgag
    42121 cggaagaaga taaggctcca tcaatgccgc cacctctcgg gccgggggca aaggcaacga
    42181 taatcgatcg gcgtgccgat ggtggtgcgt attgatcttt tccttgctct cgctgtggca
    42241 gataaccaat ttaccgccgg gcacgagcaa gtcgctcata tgctcgatca accgttccgg
    42301 ccgcatgaaa tgcgggtagg cgctatacag gataatatag tcgaatcctt tcccctcgta
    42361 gctcatagcg tcctcttgga ggaactcgat gagcggatga tccggatatt tcacgcgtgc
    42421 tttctcgatc atttggcccg ctatatcgat cgctacgatt tgccggggct cgtacggcag
    42481 caggtaactt tccaatatcc ccgtgccgca accgacatcg aggatgcggg cgttctgccg
    42541 caggttggta cgatccaata tcgtccggat ttttcccgga tcatgtacgc agacagcgtc
    42601 ccagcgttcc gccatcgtat caaaaaaagt ctctatttga ttcatgataa ttgtccttcc
    42661 catagaaaac aatcgctgaa cagggattgt tccttgaaat gggttggttt ttcgaacaaa
    42721 ccgaacacgg acgatccgga gccggacatg gcggcatata aggcgcctcc ctcgtataag
    42781 gtatccttga tccgctcgat cacgggatgt ttcgggaata cgctccgctc gaaatcgttc
    42841 accatccgct ctttccattc ggataccggt agccggatga tctctttcaa ggaggtctcg
    42901 ggcgtggcgg gtgttaccat cgaataggct tcgggggtgg agacggctac atccggtttt
    42961 accaagcata gataataatc cttcaaggat aagtccacgg gctcgaattg gtttcccgtg
    43021 ccggtcgcga ataccggcgt gttacggata aagaacgggc aatcggctcc gatggtggac
    43081 gctatcgcct ccaactcatc cgggtgaata tccaaaccgc agaaatcatt gaccagcttc
    43141 aacataaaag cggcatcggt ggaacctcct ccaagcccgg cgccaaaagg tatcgctttc
    43201 aacaaatgga tctctagcgg gggaatctcg tatctcgtct ttagggcgtt cagcgctttt
    43261 atgacgaggt tcttctcttg gggagcgtct accgggattc cggtttgcgt gaaacaggtc
    43321 cgatccgagg cgacgatctc gagggcatcc ctcacgggga tcggatagaa gatggtctct
    43381 atattatgat aaccgtccgg acgtttgctt accacgttca gacctaggtt tatcttggca
    43441 ttcgggaaac agatcatagt atttaatgtt tgttttatgt gatacgcgaa gataagaaga
    43501 tatccttata aacgttctgt tttatagggt gaactatata tggctttaat aaggggccca
    43561 cgatgggcat cacgcgtaaa agagtaggtt tgacgttttg acattctgta atctaaactc
    43621 ccggagaagc gttttttccg ggctaaggta tgccttgctt ccgaaaatgg catagaataa
    43681 tagcatctgg ttgtcttgta gtgttttatg gaaataggcc tttttattct agcgagatta
    43741 attcatcgta tctcatattt ttaggtgaaa atagccattt tatacgggtg tatcgatcaa
    43801 ttctatagga tgcgagggct gtttcttccg tatgtatcgc ctaatacata cggttgcgtt
    43861 acctaataca tacggtcgtg ttgcctaata cagccttttg tgttacctaa ctctattact
    43921 tttgagtcca aacaggggta tttaggcaag aaaaagaggg aaaacgtatg atttcatcat
    43981 aggtctctcc ctctttttct ctatttgtaa aaaggtcttg acatcgttat tctgttattt
    44041 cgatcataat gtcaagatta tctcattttc gcttacggtc tctataatcg atacttattt
    44101 atcctttatg atttcatgga gcatggcaac cttttcttgc tcggccttta gtaatcgttc
    44161 gtaaagctcg actattttat cgatgggatt gaatgtttga ttttgaatgc ttccggctgc
    44221 agttgcgtta tcttgccatg tgccagaata aatattgata agcgctcctt cattaagctc
    44281 cgtgatcgcc tctatcggaa tgtccaaagc tttagttatc ttttccaata cttcaggttc
    44341 caattcgtct tttttctcgt agccagataa ggtggcttgt gataccccta ttttgtcggc
    44401 tagcacttct tgtttgatgc ctctccattc tctccaacgt tttaagttgg ctccatgact
    44461 atttcttctg gtaaatgttg tttccatgtc tgttcttatt gatcctgtca caaaaataag
    44521 tattaaatct gagttatctt actattgtat cagatatcca gagcaaccgc acctaatttt
    44581 atttatagct acaaattacg atgggcattg ttaccggccg taaatacgta gtcagatata
    44641 tcatttatcc ctgtcatcta ataatattag tcgtgacatt gatattttat cagggggatt
    44701 gatggtatat cagcaggcgg taagcttatt ttgtctgcga atgataaaca cagaaatcaa
    44761 tggaaactca aaatcaatat cctcaaaggg attattccga gataattagc ttagcccatc
    44821 aagtaattga tctgccggta aggaaggcgc agatgttatt gaagaatctg gatttatgta
    44881 cgatcactta tacgtggaat gacgtaagcc agattacatt ggaagtcgtg ttcaaaacct
    44941 ccacgctcac ttgccttttt aatcaaaacg atatttgtga agctgtatat ctattcttaa
    45001 ctgataataa ggatctaatg aaatatatag gccactgcgt taagacctat acatatgatt
    45061 tccttttgga tggctggacc acggataaat gccacatttc aatatgccgt tccgaaaatc
    45121 aagggtgttt tttattaata ttaccgctaa aaaagatttt atgaataagg catattgtag
    45181 ttgtttcgct actcctcttt ttcaaacgaa ctttttgtgt gttccaatga cgatggtttt
    45241 cagtcatcaa aaagaaaggc gcggtaaatc aagtttacag cgccttccat ttatttaggg
    45301 ttatgagctt tattaaggct ccgcgatcat ctctttagcg attatctcgg cctcggcttt
    45361 atcggcgtcc ttttggatgt tcggcaattc aaggccgtag cctttgatcc ggtcctcacg
    45421 tttcaacatc aaggcgatga agagggcgag tacaccgaag caggtgaaga ctgccatcgg
    45481 tatcgtatag tcgtaagccg gtttgcccgt accattgtcg atcttgcaat acgtatccaa
    45541 tatccagccg attaataagg gaaccatact cagaccgata ttctgtaccc agaaaatcaa
    45601 ggcataagcc gtgcctaatt gcttctccgg gataatcttc ggaacagatg gccacatcgc
    45661 cgatgggacc aaggagaaag cgatacccaa tacgatcatc acgatcgtgg cgaaccacca
    45721 ctgattcaag atcggaagcg tgaataataa atgcacgccg atcaacatca aggcgccaaa
    45781 gatcatgatc gtcgcccctt tacccttgcg gtcgtataaa ttaccgaaga acggagtcag
    45841 aagaatcgtg ccgaaaggta agatagccgg gatatttccc gccaactccg gatctacgtt
    45901 atatttattg accatcaagt ccgtagcgta tttcaagaag gggaatacgg ccgaatagaa
    45961 taatacgcaa agcagagcga tcaaccagaa acccttattg gtaacgatca ataagatatc
    46021 tttcaaacgg aaaggctctt cctcctcggc ttgctcgata gcgtccatcg aagcgtccag
    46081 cttgcgatcc atcacgcaaa atacgaggaa ggcgatcaaa ccgatacaca acatacaaag
    46141 acaaagcaag ataggagcgg agatactacc gaagtacttg gcggcgggaa ccgtgataga
    46201 taaagccaag gccgtaccca aacgagccgt agccatctcc aagcccatag ccaacgccat
    46261 ctcttttccc ttgaaccacc gtacgataat cttagatacc gtgataccgg cggtctccac
    46321 gccgacaccg aagattgcgt atccgagggc ggccaccatc acttgcgctt tccatccgaa
    46381 aagctctcct tccatcgtaa acgcgtccga gatggcgtaa tatttaatgg aacaaccgat
    46441 aatcatcaag atacaggaag cgacacccgt gaaacggaca cccatcttat ccagaacgat
    46501 accaccaata atcaacatga aaagaaatac gttgaaccaa ccgtaagcgc tggtgaacca
    46561 accatattcc gtactcgtcc agcttagctg ttcttccaac atcggtttaa gcggagccat
    46621 tacatccgta aggaagtatc cgcaaagcat cgtgaatgcc gccaaagcga gtacactcca
    46681 gcgtgcgact ttcgagtcac ttagtttctg atgaattttt tctatcatga tatttgtttt
    46741 atagagttat attatttgta ttcgtcttct ttcatgaaca aggggagagc gtccgctacg
    46801 ataaaggtgc ttccgccgat aaagatcaag tcatccttgt cggcactttt taacgctttc
    46861 tcgaccgcct cttccaccgt ttcgcaaagg actccgggca gtcccttccg catggctttc
    46921 atggcgaaat cctttacggg catcgctctc tccacggagg cttgcgtgaa gaaataagaa
    46981 gcatctggtg gcatcaagga taatacgccg tcgatatcct tgtcgttcac cataccgacg
    47041 atcatataaa tttcgcggaa acggcttctc atggcattca ggtgttccgc tatgtgtttc
    47101 catccaccca cgttgtgccc ggtgtcgcaa atgacggtcg gttttgtccg caaggtttgc
    47161 cagcggccca tcaaacccgt cagttgggtc acgtgcccga acccttcatg gacggcctcg
    47221 ggcaggatgt caacaccgca cttctcgcgg agcaggtgca gggcggagaa caccgtgatg
    47281 gcgttggctt gttgtacctc tccggcaagc tcgccgatca cctcgccgta ttctacggag
    47341 gggaacttcc agtgtaccat cgacaaccct ccggtcccct ccagcattcc catgctcaag
    47401 gcgtagtgga agggtgctcc tgcctttctc gcctcgttct ggaagaggtc gaaaacggag
    47461 cgtttctctg cctcccccag aaggacgggt acgccttttt tgataatgcc ggctttctcc
    47521 gccgctatct tctcctccgt atctcccaag aattgcgtat gatccagact gatattcgtg
    47581 atgatactca agatcggagt gataatgttc gtactgtcca aacgaccgcc aagcccgacc
    47641 tcgataaccg cgtaatctac ctgctggtcg cggaaatact caaaagccat gctggacgtc
    47701 agctcgaaga aagaaggatg gagaggctcg aagaaagaac gatgacgctc gacgaaatcg
    47761 accacgtaat cttgggagat ctttttcccg ttcacccgga tgcgttcccg gaagtccact
    47821 aagtggggag aggtataaag cccgaccttg aaaccggatt gccggagaat ggccgccaat
    47881 agatggctga ccgagccttt gccgtttgtc ccggctacat ggatggtctt ataggcttta
    47941 tggggatttc ccagataatc atctagggcg atacttgtac caagaccggg tttgtaagcg
    48001 gaagctccgc tgtgttggaa gaccgggatg ctggtatata gatagtgtag cgtttcctcg
    48061 tatgtcatgt ttttgtaaat tagatgctac aaatgtagtt aaatttattt atacctttgc
    48121 gactcgttta taaaaaggag agaaaaagaa aatggaaaca cgacgtataa cctatacgcc
    48181 tcaaggaggc gtttgttcta agttgatggt gatcgatgcg aaggaggacg tgatcgagaa
    48241 tgtgcagatt gtaggaggtt gccacggtaa cgggcaaggc atgtgcgcct tattgaaagg
    48301 tatgcgcatc gaagacgcta tcggccgttt gtctggcatc gattgtcatg gaaggggaac
    48361 ttcatgcccg gaccagatgg cacaggcatt gaagcaattc aatcgatgat cagcttatat
    48421 ccgattcccc ggatattcaa aatcttgata gactcgtctt tcgataactt atgacgtagc
    48481 ttggtgataa agacatgcag gctgcgtgcg ttgaagaaag aatcatctcc ccaaaggtct
    48541 atcaagatct cttccatcgg taatacttgg tccttattgt cgcaaaggcg cttcaatatc
    48601 tcggattccc ggttgctgag gagttgtttc tctccccggt agaccaatgt ctgcgtgatg
    48661 gaatcgaacg tataaagccc gatacggaaa gaggtggctt ccggtctttg gacggacacc
    48721 ttatgcagta acgccttgat gcgcacgatc aattccgcca tgccgaaagg ctttttcagg
    48781 taatcgttgc cgcctgtctc gaagccctct accacgtcgt tggctgcgga acgggctgat
    48841 aggaatagga caggggtatg cgtatccgtc ttacggatca atttgaccat cgtgaaacca
    48901 tccatcttgg gcatcatgat atccgctacg ataatgtccg ggttgatctc cgcataacgg
    48961 gagaggccct cctcgccatt cgccgctagg gtgatatcga actcgttccc atccagcgta
    49021 tccttgatga tcatggccaa tgtaggctcg tcttctacta gtagtacttt tatcttttcc
    49081 atatttgata cttgattttc ggattattat ttaaaatgca gggtaaaggt ggagcctttg
    49141 ccggggacgc tttccacacg ggctgttcct ccatgtttac ccatcatgtc ttttacgtaa
    49201 tataatccta ggccataacc tttcacgttg tggatattcc cgctgggaac ccggaagaac
    49261 ttgtcgaata tctgccgctg gttggcttcg ctgatacccg ggccgttatc ggttatggag
    49321 attgtcgttt cgtgatcgtc ttgccgggct gtcgcttcga tgcggcaagg ttccttgtcg
    49381 gcgtatttga tcgcgttatc gataaggttg ctcaacatat tatataggtg ggtacgatcg
    49441 gccaccaatt ctatatcctc ggggatggag caagtaaact ccacgggttt gctcgctttc
    49501 agtttgtatt gctcgatgag ggagttcacc aactcgttta atgagatggt ttcggggcgc
    49561 aagcggaagg tactgcggtt ctctacggcg agtgtcaaga tttgttccac caatccggta
    49621 agatggataa gttggtcttt aacgatcgtc aggtatttct tctgtttctc gttgacggga
    49681 tcgctaaagt tcaataatgc gtctacggcg gcatagctga cgctgatcgg ggttttcagc
    49741 tcatgcgtca tattgttggt gaaatcggtc ttcaattctt ccacggtctt ttgctttaag
    49801 atggtgcgga gtaagtatat gaaagcgcaa atgatcagca aaagcaatag gaaggaggag
    49861 atcaggatgc ctttcatctg ggtgagtatc acgctagccg gcgatttgag gaacaggcga
    49921 tattgtaacg tgctctcgtt atggagcggg taatcgaaat gcacggggtt tttccacgta
    49981 gtgaatcgtt ctggcttgtc cagatgcatc caacccttct cgtccccgtt gtttggttta
    50041 taaatcgtta ccagctcatg ttccgttacg atgtttcttg cctccagttc cgaggttaat
    50101 aatttgttgt aggtcttgaa atcaattggt tttatagaat ctatattcgc gtgcatcgct
    50161 tgctgcacca tgtcctccac ctcgccgatt acatataggt aatccgttag ggtagagtct
    50221 atcgagctaa agtcctcctc atccccgtaa tcgatatgta gtttcatgtg tgagtcggga
    50281 tttgccgtct tgaagatatc ttcccggtta aggtcaggat cttctttctg cggatggatc
    50341 gaagcttttg cgtccatctt ctgcttatta gacggatcta gctctgagct gaagtacaca
    50401 tcttgggttt gaggtcccag cgctccctgt tcttttttga tagatcggat gcgcaggaac
    50461 aactccttat agtcggcgat cttcatcgct tcctctatat tgatctccat ctgtttatat
    50521 aatgtatcat ataaaccttt cagccagtat ccttggaaaa ccaaaagccc ggccagcgat
    50581 aggacgatca acaaagcgat taacttaaaa cgaagtctga tgttcatgaa gtctctttat
    50641 gcttataatc gaattgatcg ctaaaaatag acaattttat tacatgaact tttaatacgc
    50701 aagataaact ttatgcgggc gcttgtaaat atttactaag gatgcccatc aacgccccaa
    50761 tatcaatcgg tttagccaaa tgataattca tgcccgcttt gatagcgttt gtcacgtctt
    50821 cggaaaaagc gttggcggtc atggctataa ttggcatatg tgcgatatcc cttcgttgga
    50881 gggaacgaat ctgccgggtc gcctcataac cgtccatgat aggcatctgg atatccatca
    50941 gtattatctg gtaaaatcct tcttccgatt gggcgacttt atgtacggcg tcgagcccat
    51001 ttatcgccgt atcgatagtg ataccggtgc tgccgatgat ctctacggcg atctcacgat
    51061 ttaactcgtt atcctccacc agcaagatgc gtttgccgga ataatcggcg tttgataact
    51121 tgaatgggcg gatcggttcc ggttggtctc ctttgtcaag gaaagatctc aatacttgga
    51181 gtagcttgga cttatagaga ggcttggtga taaatccatt ggcctttacc tccttagcct
    51241 ccgcctcata ttcctcaaga tcgtatgcgg agagaatgat gatcggtacg tccgctccca
    51301 cgaaacgtct gatttgccgg gttgtttcaa tgccgttcat ttgaggcatc ttcaagtcaa
    51361 tgatcacggc gaaatactct ttctccgcta aatgatgctg tcgtactttt tctatagctt
    51421 cgctacctga atatacgcat tcactgttta tcccgatctc tcgcaaacag ctagacgtgt
    51481 ttagacaagc gatcttatca tcatctacca caagaacctc taaaccttct acctctatct
    51541 tatcatcggg cttctgatcc cgacaaacca atggcatgtc gatggtgaag cgggaacctt
    51601 tgccatattc actctccacc ttgatatctc ctcccatcat ctgaatgatc ttatggctga
    51661 tcgacatccc gaggccagtg ccttgtatcc tcttgatctc atcatcgctc gcacgctcga
    51721 aaggctcgaa aatcttatcc agaaactccg gtttcatacc tcttccgtta tcctcaaaca
    51781 cgaattgata atttccgatg ccgttatgag ggtccttctc gtagatttct atcgtgattc
    51841 gcccattctc cggcgtatac ttaattgcgt tcgagaggat attcatcaat acctgtttga
    51901 tacgctgcgt atcgcctttt acattctcat gcctaaggtt cttgacgtgt atatttaaag
    51961 tttgttgttt gtttttgatc tccggttgca tcataacgac caagtcttgc aagagctcac
    52021 ccacattgaa ctcatcctcc gaaagaatta acctgccact ttcgatcttg gacatatcga
    52081 gaacctcatt aatcagactc aataataatt tagaggctcc attgattttt tccatacaat
    52141 ctaatattct ttcacgttca tctacatggg ctttggctat agtcgccatt cccatgatgg
    52201 cgttcatggg tgtacggata tcgtggctca tgcgggcgag aaaatcagat ttggcttggt
    52261 tggcttgttc cgccgacttt agtgcttctt taagttgctt tgactgtttc tccagtttct
    52321 tttgcaactc cctctgttcg gtaatgtcgg tgatattgat gtaaacgata agatagatag
    52381 gctcgtcacc ttcccagccg atacattccc cgttcaactg tagccaagcg ccgttgccgt
    52441 ttttgtcttt cgactggata acgaaatgta caggttcccc ttttagcata caggggatat
    52501 gtgcgttcat cgtattacgg cttgtttcat ctaaacggga gaaaggactg aaagataaaa
    52561 aagaattttt atcgatacca gagaagtcca tatatttatc atttgcctcc agcaatgtaa
    52621 aactgccgtc tttatgtacc ttatgcttgg atatgaagcc ggggatatta tcataagtga
    52681 tcgtttgctc gatccgcctt cgcattacgt cctctacatc ggtcattacc gtataggaga
    52741 tagggatgcc gtcttgtagt tggtcggtaa acgttgaggt gattttagtc catcttttcc
    52801 cttttctcgt tggcatctgg ataacggttt cgtaaccgct ggctttatta gctatcgtct
    52861 cgtaaacatt cttggataat atattccaag cttcatcata acctttaaaa tacaaatcgg
    52921 gtttattgtg gaaaagagct tcatattctt ctttggggta acctatcata tcgtaataga
    52981 agtcatttgc ccataaaagt gtgaaatgct catccaataa atgtttgctg acgctagctc
    53041 ccgtaagccc catcaataag ttgtattcta gatccgtctc tcgcccttcc atcgtatgtc
    53101 tttttatatt attctacaaa agtaaaaatt ataaaaggta cccttgaaat tcttcttttt
    53161 gataatatgt tccgtttttg ctttcggcta gtcggatgtt ttctggtaac aagaataggt
    53221 atacgattta cccctgtatt cttgtggagt catgcctaca tttcgacgga agaacttatt
    53281 aaagaacgat agattattaa agccaaggtc catcgctgtg tttttgattt cttggttagt
    53341 cccttttaac tgtgtcttag cgtctatgat tattgtttgc gtgaggatct cttggggagt
    53401 ctcgccgatc gcttttttga tggatgtcga gaaataggag aacgtgaggc ccaacttctc
    53461 ggcataaaac gatacgttat gctcttttgt atagtatctt aataccatat ttaggaactc
    53521 ttgatagatt tgtaacggac gtgtaagttc ctgtttctct aatgggtaat ttttactgta
    53581 tatttctgcg ataccttgac tacacatcat aaaaatggcc tttatcatct ctttattgtt
    53641 caagatatcg ggatatacgg catattgata gagaagctcg tagaagttcg tgatcaggtt
    53701 ggccctgttt tgggatattt ttataatcgg atacctgtaa atcataagta gataacccat
    53761 cgtgctcttg ataaaatttg cgtaacacat aaaatcgaaa gagaacgcta tgaaatagat
    53821 caagatgtcg ggggatatct catgtatttg tatgcgacta ttgggcaata gcgttacaac
    53881 attgagtttc gaggtggtca attctgacat attgatagtt gagcgtattt gcccttccat
    53941 gcaaaggata aagaccccgg cttttatctt acaaggaata tttataaact ccttgagttc
    54001 atcggcggat atgtatttac caaccataaa gtctgtaggt gaatcaaggc agaggaactg
    54061 tttatccata ttgtaagatt tttgacgtca aatataaata ttaattgaaa ctcaaatgtt
    54121 gtaaaaggaa atatggaaca tattatccca aaaaatagtt agccaagact aaataagatc
    54181 ctttacaccc ataaacttga annnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    54241 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    54301 nttaattgaa actcaaatgt tgtaaaagga aatatggaac atattatccc aaaaaatagt
    54361 tagccaagac taaataagat cctttacacc cataaacttg aatggttgcg ccggcttaaa
    54421 gtcttttgaa gtgttgccat gataggtctc accgttggcg atggatagtt taagtaccgg
    54481 cgcaccctcc gataagtcca tgtctctcag tcgtacccag aaagtgttcg gggtcaggct
    54541 cgactcaaag aaataaatca ggttcttgct ttcggatacc gttctccatt gcgtggtgga
    54601 tatctccgga ctctcgggag tcgatatgcc ataagggaca gaggcgttac ggatcacgct
    54661 gaatacacag gcgatagcta tcttctcatc gtccgtctta agtacggcat ctatataaaa
    54721 actagctctg gcaaaacggt cggatgcacg gttggtaccc ggaaggaaac tcagccctcc
    54781 gatcgatttc caatattcac aaagagccaa ctgtttatta taagtagggg agttagtcat
    54841 caccttgtat tccttactgt gataaacggt cagtttacct cctatgtatt cgaagatagc
    54901 gcaatcaccg gttgcgtcgg aaatcgataa atgtaaggtc gccaagcggg aaccgtccgg
    54961 catcttatcc gatactactt gaaacgtatc ttcgttgata aaagagaccg cttcttccac
    55021 cgtagcgaaa ttatccaaca tatattgtac ccatatcgtt atggcaaggc ccggtttatt
    55081 cttatctctg gccggatatt gggcttcggg taaccagagc aaattagcta ccaaaccttt
    55141 ctcgttcatt ccgtccgtac tggctatctc gaaagcggag gtgatgatgc tgccgtattt
    55201 ggatttccac tttaaagaat cctttcctgt ctccccgttt ctctccatcc ccctaggaaa
    55261 cacccatagg ttactatgca tatcggtctt ccagtccatc gtgcgaccag tcgctaccat
    55321 cccgtttgtt cccgaataaa ctactcttgt acacatgatt ttcaactttt aataggttat
    55381 cttcaaatat ttgattgata tatcaacagt tagaacctct taatgttcag tttacgtttt
    55441 cgcatcaaag agtacggcgg cctcgaaacc tttttcctgc aattccctta ggtgagattt
    55501 agcacaaagg ataccattca tactactttt ctgaaggtgt tttccagatt atcttgttcc
    55561 tctttgttgg gtttgataat tggcgataag actaaataac attcctgata agacaaggta
    55621 agacttcgta agtgagtggt aacatagttt cttttaagaa tacgtttctt ttgtatgaac
    55681 gaaaaatgat aaaaacaaac cgatatgaaa cgtactattt actacatgat tttatgcttg
    55741 ctgatgagtc tcggtgagat tatggcacaa ggtatttccg gaaaagtgat ggatggcaag
    55801 gaacaaccga tagatggagt ggcggtgatt ttacagaccc ttgactctgt atatgtggat
    55861 gccgtggtta ccgatacgct tggggatttt cgattgaatc atccgctaga ccagtcgtat
    55921 cgacttattt tccagcacat cttatataat acgataggga aaaagataac taccgccaac
    55981 gtaggtacgg tggtgctgga ggagaaagat tatcagttag ccgagattac cgtaaaggga
    56041 gaacgcccgc aagtgaaact ggagggaggc aagctgacct atgatatccc tcaactgatg
    56101 aaggataaga ctgccacgaa cgcttttgag atcatcaagg acttaccggg gcttatcgag
    56161 cggaatgata atctggaact ggtaggggcc agtcgtttga atataatctt gaatgggcag
    56221 ttgacgacaa tgtcggcaga tcaattaatc cagttactga aaactatgcc agcctcaagg
    56281 gtcgaaaagg ctgaggtgat gtataacgct ccagctaaat ataatgtcaa gggggcgtta
    56341 ctcaatgtcg tattaagtaa gaatgagtcc gagactcctt cttggcaagg tgaaacgggt
    56401 gtggattaca cccaatatcg ccatgcgggg ggagatgcgc atgtgaattt actttatacg
    56461 aataagggct ttagcttaga tttcctgttg aatggtaata agagacggga tgtgatgggg
    56521 gaggatatgt tggcccgcca tacattaaat agtggtatga cggaaataag ccaacataat
    56581 cgggcccttg tccatgtaaa tagaggaacg gttcgtctgg gaatggatta tacgttcgcg
    56641 aatgaggata aactctcttt ggcatattat ctgaagggag ataaagtctt atcggaccgt
    56701 gatgccttta cctcatatct ggatctgtcg aagccggaaa ataaaagtga gagtacgagc
    56761 ttggtccgtg acgacgggca ctccgctatc cataatatac gtttacagta tgacggacat
    56821 gccgggatat cggcaggagc ggattttact cgttatcatt cgccctcggt acttgattac
    56881 catgatacga atacgaatgg ttcccggact gatatgataa ataatacgag acaggatgta
    56941 tcccgctggt ccgtattcct aaataagaca catagtttcg cttccgggtg gggattgaat
    57001 tacggcgtgc atggaggtta cgcctcgtcg aaaaactatt cggagtattt atatgagcaa
    57061 ggtgctggct atgagatgga cgaggaagcg ttggaggata atacacaaaa ggaatacatc
    57121 gctgatattt tcgcagaggt atcgaaaagc ttcggagagc gtttctctgc tacggttggg
    57181 ctgaaagggg agtattttaa gtctgactac acctctagcc gggaaaatat gaacctatgg
    57241 aatgaggggg cgttgtttcc taccgtatcc ctgagctata cgttttctcc ccgccatatt
    57301 ttacagttcg atataagtag cgataagacc taccccggtt attggcaagt ctccccgcaa
    57361 gtaacgcctc taaactctta ctcggaggtg gcgggaaatc ccttgttgaa accttatcgc
    57421 acgtatgagg ggcagatggt ctatatcttc cgccaaaagt atatgctggt agcgttctgt
    57481 gaatacacgc cggattattt cgcccaactt ccttatcaaa gcgatacgga actgaagacc
    57541 gtttttcgtt tcgagaatat ggattatagt ctggaaacgg gattggcggt gatcattcct
    57601 tttaatgtgg gtcgtttttg gaatagccgc atcacactgc gaggttggag gatgcaagaa
    57661 aagaatgata acttccacgg catctcatat aaccgtgagg cttatctagg attagcgcat
    57721 atgagtaaca catttaacct atgtgataaa ccgaatttaa aaatgacgat agacggccaa
    57781 tacgtgactc ccggtgctat ccaaggtata tacgacttgg gttccatgta tgagatatcc
    57841 gctggattaa aatggacttt cttgaatgac cgtgccagct tgacacttaa aggagacgat
    57901 attttcgcca gcagcattcc acgtaccatc aagataaacc aaggcaatca atggagccgg
    57961 atgaggaaat tgaatgatga gagatgtctg aaattatctt ttgtctggaa gtttggtggt
    58021 tacaaggaga ggaaacatga ttcgatagac acatcccgtt tcggaaaata atagatgcct
    58081 tgtagtttca tcctaatgaa ctctttgttt caataggatg aaactggatg ctcttctaaa
    58141 ggaaatccta tattgctttc gtactcgctt ctatctgttc cattagcagg gtgatattgc
    58201 tcatgaatag cttgacggag atcgccagca ggatgatacc gaagaattta cggatcaggt
    58261 atatgccgcc tttccccaag actttctcta ccttgcgtgt catgcggaca acaaagtaga
    58321 cccatagcat attcagtacc aaggctacga taatattcat gctggcatat tccgcacgga
    58381 gcgacaacaa agtggtgaac gatcctgctc cggctagcaa cgggaatacc agcggcacca
    58441 acgtagcctc cttgattggc ccttgattct tgaaaatctc tatgtcgaga atcatctcta
    58501 aagataggag gaagatcaca aaagcgccgg ccacggcaaa cgactcgatg tccacatgga
    58561 aaagcctgag taatatatcc ccggcgtaga agaaccctaa taacaataga aaggagatta
    58621 aggttgcctt caacgcattg acatccttgc ctttatcctt taggtctatg atgatgggaa
    58681 tagctccgat tatatcgata acagcgaata atacgatgaa tgcgctaagt atttgttgga
    58741 aattgaaatt tgtgaacatg acgttaccct cctctatttt ttaatcctcg taaagataca
    58801 tatttttcct tgaattggtc aatatgacga aattattggt gtgtgtaact aattt
//
LOCUS       DBMDTB010000011        55195 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_242_length_55195_cov_8.023015, whole genome shotgun sequence.
ACCESSION   DBMDTB010000011 DBMDTB010000000
VERSION     DBMDTB010000011.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 55195)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 55195)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55195
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_242_length_55195_cov_8.023015"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(30..602)
                     /locus_tag="ACZPB4_03240"
     CDS             complement(30..602)
                     /locus_tag="ACZPB4_03240"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097269.1"
                     /translation="MRNCWVSILALVMSVIALMLSYRVAPIDFKDYWGFVLGVQSLLV
                     TILIGWQILNVFEVKRQIEDFNETISKLKKENENIIHDKISDYDLTVSALFQQLEGIR
                     QFNSGHGKDALAFFMKSLKLLNAASDKTPIDGLVSYILGIKSEKLYVSPISKEDVDLY
                     LQIISNCTSEKKPELLKYVMSLPVSEKNDN"
     gene            complement(612..908)
                     /locus_tag="ACZPB4_03245"
     CDS             complement(612..908)
                     /locus_tag="ACZPB4_03245"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097270.1"
                     /translation="MKDRKVGRFVRARYYNNIKSFTSDPTDRDIIEEHLIREKWLKRS
                     DDNKRSISITEEGLCVLRTGLIETEVRAMLNNYIMVAFSIAAFVISVLAFISKN"
     gene            complement(1128..1556)
                     /locus_tag="ACZPB4_03250"
     CDS             complement(1128..1556)
                     /locus_tag="ACZPB4_03250"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097271.1"
                     /translation="MEDLWPDFEFESSMTPKEILLTQADFLSKKTSGVLIGEVHTCEP
                     NDYLLYHALKCPSVSNPDLNKPIGHVLYIRAPFFNDYRFEILSITHYLLNMYPLQLNN
                     VLNNCYYTIDSEEYLMKKLSEIFASKDVLSILNSLLIQSK"
     gene            complement(1561..2379)
                     /locus_tag="ACZPB4_03255"
     CDS             complement(1561..2379)
                     /locus_tag="ACZPB4_03255"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HIR1097272.1"
                     /translation="MRFLFWNIHKNESLFSSIASIAEAENIDVLMIAECPENKQLDLL
                     KSLNANNSDIFKYLVPIVNYQKVMVYYRHCKITNKEDKPRISVKELYSPLLQGNITLV
                     ICHLHSKINNSDEELSEKAESLRRFIEDIESKLGHQRTICCGDFNMNPFDKGIIKAQG
                     LHAVMEKNIANKKECIIEGEKFSFFYNPMWGFLGDLGRGDVSGTMYYNSGGHINYYWH
                     LYDQVLIRPDMINSFDESDLKIVTSANKLDLLTSNNLVDKSLSDHLPIKFNLKI"
     gene            complement(2388..2531)
                     /locus_tag="ACZPB4_03260"
     CDS             complement(2388..2531)
                     /locus_tag="ACZPB4_03260"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097273.1"
                     /translation="MEDLMDKDKTIAILRHQYERERKENQILKEEIALLEYEIEQLKQ
                     QIK"
     gene            complement(2545..2889)
                     /locus_tag="ACZPB4_03265"
     CDS             complement(2545..2889)
                     /locus_tag="ACZPB4_03265"
                     /inference="COORDINATES: protein motif:HMM:NF024835.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIR1097274.1"
                     /translation="MNVIDNIFKIMAQKGIKQRTLADAMGIDESQISVMKKGNRDLKI
                     SEIENIASCLGISITDLFTWPERYVPEQSAGEKVLTTPKVILQLELEDSDVKADVIKL
                     AFGDRVLEIKNK"
     gene            3071..3331
                     /locus_tag="ACZPB4_03270"
     CDS             3071..3331
                     /locus_tag="ACZPB4_03270"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097275.1"
                     /translation="MEKLNLQGHETGARSFREIYFSMDNTPPKKAFIQKIATITKRSE
                     SAVRCWVAGVYQPDALAQEVIERELGIPASELFPKEDKVCAQ"
     gene            3319..3876
                     /locus_tag="ACZPB4_03275"
     CDS             3319..3876
                     /locus_tag="ACZPB4_03275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HIR1097276.1"
                     /translation="MRAIEFYTTPSGEVTIKEQGQPERQLKESDTDFIQSFLEILEEF
                     YTEAYAALRKYYARYDGNKCYRDFLAVRRFIKCNFGLYDNMIDVDENWNFKFEFVGCP
                     LRGECDGFKKICEPKFNSTLSDSQLRVMELCYYGKKDEEIAETLFISSHTVKNHRKNV
                     FRKLSIHSMAEFMRYANEKNLFKGE"
     gene            3879..4136
                     /locus_tag="ACZPB4_03280"
     CDS             3879..4136
                     /locus_tag="ACZPB4_03280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097277.1"
                     /translation="MPTENTYQSIPSLRKIEIEYLAWQITRMQAGIREFIGQKEAHLR
                     FGRQNVEKWVSEGRLQRYKRPGKIEYRLENLYKCALNPYDY"
     gene            4254..4424
                     /locus_tag="ACZPB4_03285"
     CDS             4254..4424
                     /locus_tag="ACZPB4_03285"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097278.1"
                     /translation="MKTDYWKLAQAVRWGFYILFGTLAILGIVAICLGHFLHIITTSG
                     CAAMAYMIAKHW"
     gene            4448..5449
                     /locus_tag="ACZPB4_03290"
     CDS             4448..5449
                     /locus_tag="ACZPB4_03290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010803586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HIR1097279.1"
                     /translation="MSNLIQIKVAELNQLDPLMIAEDNRVEQKFIQMYNAIWGTAQGA
                     QIYEKEKFNFRKILQDKPELQKCTPLSLYGCFLDIAVNGLSLDPTGRPHCYILPRSTK
                     TGYKDNNGSDIYELRAYLSITGYGELVMRQRAGQVRYVDNPVVCYEGDTFSPGLIDGV
                     KTVTYQAACPRKSNKVIGGFLRIVRSDGTVDWHWMMEGDIKRLEVYSFKNNQKWNPQT
                     RQKEGKANALYTSSEGGIDPGFLESKLIKHAFDGYPKVRTGQFSSFETQEEPQEIDYG
                     LEETTVIQPNQAGQQPQALQPQSENPLQGFGEQPQAEPIPVSGITAQISQEDEEAGF"
     gene            5483..6136
                     /locus_tag="ACZPB4_03295"
     CDS             5483..6136
                     /locus_tag="ACZPB4_03295"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097280.1"
                     /translation="MDTQNNNLPFKANEVISILQTAPDILARNEPSVSACTNAGKTLL
                     DTIEGNGGIGTDEIDTAVQEYLAKSKKTVENMNNRRKPLTQMLTAISKRFTTLEGSID
                     AKSKGTIPYLLQMERNKYAAKKLEEQKRREEEARQKQLAENEKAQYRADITVLLDTTY
                     AAYVEKHINALNGIFNRASLATYGDVCRQITQTSTGFSWTDFVKNVVDNKTDILYGR"
     gene            6126..6701
                     /locus_tag="ACZPB4_03300"
     CDS             6126..6701
                     /locus_tag="ACZPB4_03300"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097281.1"
                     /translation="MDGETRKAIKNEIAILKKKEYSDRYAFEIEGLKQSLVDRLPSLR
                     KQLEEQEEIRKTNAIEAARLEEERKRKEAEERQKAELERKRKEEEARAKAEAEKATAE
                     VQAAFDFSAASMSPTPTKAKIKKKIQVTNPQGFMQVYQMWFMREGINMSMEDLEKIHK
                     KMISYCEKTANKDGERIQSAFVKYVDDITAK"
     gene            6884..7534
                     /locus_tag="ACZPB4_03305"
     CDS             6884..7534
                     /locus_tag="ACZPB4_03305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease-like domain-containing
                     protein"
                     /protein_id="HIR1097282.1"
                     /translation="MQDTYYQRSEVSNSDLTELKNLLYPRTQYGDKEKAFKFGSLVDA
                     MLTEPERVRYDKHTVDDVLYSGEDWELAQAMIKSLRMEARHDPLLAQVLAKAETQRFM
                     VNKGQRFQYGNFEYTLDTRCKWDWWLPTFGFGGDLKTTFASSQKQFDEAIDFFDWDRS
                     RAWYMDIAGSRQDFIYGISKKNQKVFKAFIRRNDPSYRKGKEKYEELAFRWWMLIS"
     gene            7539..7706
                     /locus_tag="ACZPB4_03310"
     CDS             7539..7706
                     /locus_tag="ACZPB4_03310"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097283.1"
                     /translation="MKSLVLILIDWLKCRLAKKCPICGASVLVKKLQTHTGNTFNVYH
                     CGNCGNDYILK"
     gene            7712..8131
                     /locus_tag="ACZPB4_03315"
     CDS             7712..8131
                     /locus_tag="ACZPB4_03315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010803590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097284.1"
                     /translation="MNLNITPTDKISKELAAIDAFLNITMSEDVQEAVLRGNDLAVYI
                     ARTGKLLADAKYHLNVKKKSEVFDTLRETASRAGATSKAVNAIIDSLCKDEQYLVDWC
                     DRLNRTATHQLEWCRTIISKAKAEMALAPQSYNNPKF"
     gene            8138..8785
                     /locus_tag="ACZPB4_03320"
     CDS             8138..8785
                     /locus_tag="ACZPB4_03320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097285.1"
                     /translation="MEELVKEQPVYEIQKVKIKNNQLTAEYTEKFVEANYKNNILKES
                     EQFIHPDLLYALNRLKPHVVKICEMHEATLVNVANPSDDDLNEKLKNIIVTGYSKGGN
                     DESAGVSIQAQKLLKSGQILNLSVPFTKYEDESGDGYLYGAELKEAIGRCSYEVDAYL
                     FEGKYGIKQESFDFDTPEESDITGEKEEKPKKRGRKKKEQIKEIAEEVKAFDEFA"
     gene            8807..10498
                     /locus_tag="ACZPB4_03325"
     CDS             8807..10498
                     /locus_tag="ACZPB4_03325"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HIR1097286.1"
                     /translation="MQITLQNTEKGQCYAVRFDRYRQQVVDKLKTAVSVRWWDKSTGA
                     WMIPANNKCKAELDQLTYYVRHFEPVNWGGNESKTDEDIAYQIPDMPELDEDHGLKIQ
                     PYPYQLQGIARGLQLKRFINGDDMGLGKTLESIATINKADAFPCLVICPNTVKINWQR
                     EWHKFTDKKAMVLTDSVRTSWPFFWQTGMNHVFIVNYESLRKYFVRRINKSEKWTLKD
                     VEFHNTIKLFKSVIIDESHKVKSTATQQSKFCKGITAGKEWIILLTGTPVVNKPNDLI
                     CQLAIMDRMNDLGGWKYFTSRYCSGPHGASNLKELNFMLWKHCFFRREKSKVLTQLPD
                     KVRQIVTCEITNRKEYQDAERDLVDYLRRYKEADDEKVQKSLKGEVMVRIGILKDITA
                     RGKLREVIDFVKDFRENGKKIILFCNLHEIVDRLLQAFPSAVCVTGRQDMQQKQAAID
                     AFQRNPKTDVIICSIKAAAAGITLTASSNVAFIELPWTYADCDQAESRAHRIGQKDSV
                     NCYYLLGRKTIDQKLYRIIEEKKHISNAVLGAKDNIQTNIVDMMARIFDETEEEE"
     gene            10501..10725
                     /locus_tag="ACZPB4_03330"
     CDS             10501..10725
                     /locus_tag="ACZPB4_03330"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097287.1"
                     /translation="MAEEYIGINRLKEREDANKYPRRKCVRCIRYPCFSGQGIGTHAI
                     NLAAYGCKDYKSQTRLKNMSHNVNKGGSDA"
     gene            10748..10993
                     /locus_tag="ACZPB4_03335"
     CDS             10748..10993
                     /locus_tag="ACZPB4_03335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097288.1"
                     /translation="MISLIFILTSGISIQFKPFHISLAYPYFGTGMVLIAIGFALCFG
                     SAYYHGISNHEYKDGYSKGFNAGIEYIIDWAKNKKEG"
     gene            11109..11672
                     /locus_tag="ACZPB4_03340"
     CDS             11109..11672
                     /locus_tag="ACZPB4_03340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097289.1"
                     /translation="MASEALNKYIEKRYDRWLDYAKYHCSLAGMSSEAIDVLNEVMCM
                     LLQKPLEHLSRLMEAKQGKYTELDWYILQMIKLNVTSDTSPYRHKYKPIPVDENVDWR
                     RLNIIDEPDDSIDRTEYIRERMQDIRDMVDLLELSEKAKRIFAWKFFAGESFADWPGP
                     ESRKELYETYKSVFNAVMDKKDGRLLF"
     gene            complement(12332..12964)
                     /locus_tag="ACZPB4_03345"
     CDS             complement(12332..12964)
                     /locus_tag="ACZPB4_03345"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097290.1"
                     /translation="MYSSKRISKFYQIRGQWDSVDKSFVDYVNSGMALVQSEKRFFDA
                     KSEDELCGDKAIDVMFLEKAFLNGGLIYLFSQLEYYLHFAKREISRLLGKEDNTKFTR
                     NIIKNEVKHIFSFRRETIDSIPSLNEKWKVILLYRDIRNVFVHDNGITDKPEVFYNII
                     FNNRISSLVTCILSYYQRTEICITKDFVLQVCKDITLFFNELLDHFDTRC"
     gene            complement(13133..13723)
                     /locus_tag="ACZPB4_03350"
     CDS             complement(13133..13723)
                     /locus_tag="ACZPB4_03350"
                     /inference="COORDINATES: protein motif:HMM:NF042453.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6549 family protein"
                     /protein_id="HIR1097291.1"
                     /translation="MKRFLIILGISLVLVGVIASLSYLLRQERKEVRRLSGNQRSLME
                     EVELYRTKDSLSAASVERLLLTKKEYEKYFSDQVKIIDNLNIKISRLQSVSETGMETM
                     YPINIPVKDSVVIRDSMVMLKCLELHTPYLDVSGCIDMGRFSGKIISRDTLDQAVHRV
                     PHRFWFIKWGTKAIRQDIVCRNPYSQITYSEYIELK"
     gene            complement(13720..14232)
                     /locus_tag="ACZPB4_03355"
     CDS             complement(13720..14232)
                     /locus_tag="ACZPB4_03355"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HIR1097292.1"
                     /translation="MTVEEFVAWVYPEACKGEISPVFVTAQAALESGWGKSGIGNNLF
                     GITKGSSWTGPVELVTTTEYFNRDNVSFKLPERVLSVTELGNGRYKYRVKRLFRQYGT
                     LADCLADHLAILKKPGYADAWPFRDNPDLFAEKLQDCIGSRYATSPDYVQTMKKLFRM
                     VERSVKTQGL"
     gene            complement(14229..14621)
                     /locus_tag="ACZPB4_03360"
     CDS             complement(14229..14621)
                     /locus_tag="ACZPB4_03360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097293.1"
                     /translation="MGVDLNTVLAVIGAMGGVEGIKWGIRAWVNRKTDARKEDAAADA
                     LEITNEKNQVGWLEDRITQRDLKIDALYVELRQEQSAKLDEIHKRHEAELALKDAENN
                     RCDRPDSECGRRIPPRRKLELKDKEEKE"
     gene            complement(14690..18418)
                     /locus_tag="ACZPB4_03365"
     CDS             complement(14690..18418)
                     /locus_tag="ACZPB4_03365"
                     /inference="COORDINATES: protein motif:HMM:NF025253.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HIR1097294.1"
                     /translation="MVIYNQAGDVLLDIPVDDDSYRYRAIAQAKKVELRYSLVEHVEL
                     PTGAYIEYQGERYTLWYPSDFKKEGTRVFDYTVTFGGNEEILKKYKYKLLSDKPYKLK
                     FVMTATPRMFVELLVDNLNLYDSGWTVGTVIEAPEKLLSFNHEKCWAVLGRLAEEFDT
                     EFEIVGKTINLRKVEYYKDAPLKLSYGKGNGFLPGVGRANQGDNLPVEILYVQGGERN
                     IDYSAYGSQTLLLPKSQELEYQGRRYKTDPDGMYVTRADRPLSSYNEDSYDASDIYPS
                     RVGTVSKTDTEPGEDTDGNDVTFYNFYDSSVPANLNFEDCLIAGQTMTVIFQTGRLAG
                     REFDVKYIHDGRKFEIVPAEQDGMDLPNSSLYPEVGDKYAVFNISLPTAYVCDNATKT
                     GASWDMFREAVRYLYEREERQFTFTGELDGIWAKKNWLAIGAKLVPGGYVDFSDPQFQ
                     PDGILIRIIGVRDYINRPHSPELELSNTPVGGFLSDELGKLESEEVTNETRHKQAVSF
                     TLRRWRDAVEMQGMLEKAFKDYGKGQAMSWLRTMSVLVGHESLQFRFVNRIPTADGQT
                     VTEVDHAFTYDGQRRTLATPSGILQHMTLGIDSLAPSHKVTEYKYWNMAAYTSPYLGD
                     DTEAMYLYARCAKSGSAGTFLLSKEPMDLDDGSYYNLLCGALSTEVDGQRSFSTLYGF
                     SEIGPGWMRLNKIINMDGTQYWDMLSKAFRIGDDNAFLSYDQRDGLVLKGSIYQSPSG
                     EIDYPEVDRGAYSDKSVYYPGDKVSYDGNVYKCISQTTPAVPVGGSYASPLPTTAGWS
                     DGVPDGESILWASTRIFTSDGKDPQQAAWTTPRQMTDTADFDVEFSSVANPSAPNGHP
                     NTNTQWSDTQSTDTIWMATSTKRNGVWSAWSVSKIKGEEGKPGKDGKDGDPGPRGDRG
                     PRCTYRGDYDSSATYNASSKITDIVSIKNSDGTRSYYVAKVDDNEPTFKGKHPTNTAY
                     WDTFGANFSSVATDLLMARKIAASEIDVEEIFANLARIGNFTITNGSLIVDTSVSDRT
                     QITFPRMLTIGKTTQFAGQFGDRSSWGGVFFEGFGPYFYDMGVEKVLYREGTGVVFNA
                     PGGRYPFLGVRIDNGNGIYGWNSPGNIANLYINKDAASTAHVYITNYQGLTSSDIRLK
                     SVFFDIPDVLDKLEGISAFYYTMKEDEDKILRIGVSAQAVREVLPEAVHLITPDDDDS
                     YYGVDYIQMLTAFGINGIKELHAKVKALEKRVEELENR"
     gene            complement(18433..18942)
                     /locus_tag="ACZPB4_03370"
     CDS             complement(18433..18942)
                     /locus_tag="ACZPB4_03370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HIR1097295.1"
                     /translation="MIYLVLISMLIIASYTAAVCIKQKGVLASISATFYRLEHKNWFM
                     ATTWLTAGLLMPAILEVSRPDTEFLAFLACAGMFLVGAAPNFKEDFEGDIHELGAICC
                     IVGSQLWVMFNCPWCLLVWVAYVVYTIVMMTRHVSDSVIADFYRTKPMFWVEIAALLA
                     TYMSVFILI"
     gene            complement(18959..19750)
                     /locus_tag="ACZPB4_03375"
     CDS             complement(18959..19750)
                     /locus_tag="ACZPB4_03375"
                     /inference="COORDINATES: protein motif:HMM:NF044553.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine-rich domain-containing protein"
                     /protein_id="HIR1097296.1"
                     /translation="MRRSMMGKRKKLFIKRFYPAGNYTWIVPRGCTSVDVFLVGGGSG
                     AGQISSGSSYGGGGGGYTKTYRGVGYVRPSSGSWMGTYNDGRDGDAITVFPGQIVAVT
                     VGAGGNGGDGGYSQFMDDRHRAEGGRCVKVNLHGGNGGSGGSGEDESSSVYGGNGGSD
                     GLPGGGVYRGEGQNHTTRDFGEPSGKRNAGGGTGCSHRMKEYHGGESDYEEGSGESFN
                     RRQDSYVGGKGGGGYGGGAGGTFGNNASTRGGDGTVVIRYWAYEE"
     gene            complement(19845..20864)
                     /locus_tag="ACZPB4_03380"
     CDS             complement(19845..20864)
                     /locus_tag="ACZPB4_03380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005649143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097297.1"
                     /translation="MLYIQRDIRFWNVEEQLPGSYLVSEDIEQYHNGAYLLLNAEQER
                     YHNDHPEATPLECWNMAPEPDPEPTPEELLWRARDAKRKEIYDKDIHHYYIDEQDAYV
                     SNTLQVKDKCGRQEEVEVGGHLYASNILTVALDEIADYSEQCGKVTDSLLSRIDAAQT
                     AEEVEAIVVQGYPEMIHTTTAALQTKADKAIAKSPEAQAVTFARAMMNSVSLTASQAL
                     EMQVLFPIWGEKDAEFGKEVEIGFRLRVVEGESDTLFEVIQKHKLQADWKPGIETASL
                     YKIVEAEHAGTLDDPIPYVQGMAFEKDKYYEQYGVIYLCILTTVTGYPNDLKDLPTIV
                     QEVKR"
     gene            complement(20951..21565)
                     /locus_tag="ACZPB4_03385"
     CDS             complement(20951..21565)
                     /locus_tag="ACZPB4_03385"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097298.1"
                     /translation="MRRRVMGGGKIDYDKYPNGVYILHVNGKLYTRAEWNAAWNDSAV
                     GVALKTDNCRFVIAPEGLDEDNLPWSKYGAYEEVPGVTTTTEETIAIDDYKGEANTAA
                     IVSHYGAGTDYAVGWCANYTFKNGAKGYLGACGEWLEAFNNKAEIDACMNLITGGIAI
                     KAPYYYSSTQYDFYSAWGLTWSRKDVYANSKSIGFYVRPFAPLE"
     gene            complement(21584..23284)
                     /locus_tag="ACZPB4_03390"
     CDS             complement(21584..23284)
                     /locus_tag="ACZPB4_03390"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097299.1"
                     /translation="MSKKGAFIYQQIELTTAEWMDNTTIYPPSVWLFERLGNGKFNMK
                     LADGVHAFAELPAVMQDVKVTVKQNDGTTYILTITTAEGEFDTPNLKGTAAPVPSIDP
                     ATKHWKIGDEDTGVVAEGKDGATYDDTEIQAALSTLQKQVDTLVSGNASNAIESFNEI
                     IAFLSSVEDSQTLQGILAGLSQNIANVQKAIPTKLSQLQNDDHTVKDAKYVHTDNNYT
                     ASERQKLAGVAENANNYSLPSATAERLGGIKTGYANSGKNYKIQLDPQGNAYVNVPWT
                     DNNTTYAQATSDKLGLVKTGYSTNGKNYPVSLDSGGKMYVNVPWTDTNTTYSNMGAAT
                     ANAAGKAGLVPAPGAGKQTSFLRGDGTWVVPTNTTYAKASATTLGLVMIGYAKNGKNY
                     PVELDGSGKMFVNVPWTDTNTTYGVVGANGSTGLVKNGSTVTSASGYTACPIVGGVPY
                     FKDSYTSAERQKVADSLRLKEYADVSDLGKLPATPYNLRYVYTAATPKAIAFANVGSV
                     PEMQELYLSIKNNTSSKITQPIPNGSGWQSEETSLEIEAGKTAGISIKKEHGVMVVRV
                     "
     gene            complement(23277..24587)
                     /locus_tag="ACZPB4_03395"
     CDS             complement(23277..24587)
                     /locus_tag="ACZPB4_03395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005638374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097300.1"
                     /translation="MRTKKKKISELTLADSLTGLYTIGCKVVSGTQTSVKVSLEVIQK
                     AYENMLTEISNARDAAKAANTAAASANTAAGRAETAAETALATNQVITKAETGRVKAE
                     QGRVEAENARKEAESFRGEAEDLRETAEQERATAEQSRVEAETRRDTAEAKRIESETA
                     RTESEAIRQRQEDGRVAEESKRVETEKLRSVAEALRDRSEQERTRQEETRVKAEGSRD
                     SAEQERMTNERKRVEEEAARKEEESKRVQSERERAEAETVRETAEGLRETAERARKTA
                     EGMREQQETSRQENTAVAVANAEAATQDANDAADRANAAAEAAEGVVSGLQPDWNISD
                     PVNKNYIKNKPEIPTLDMVPTADTLSYVNIDGTTINFRIGDEVRVLENGEYVFYRLYD
                     LADGIASWQESGGGTALPGNVYLTGANYYNDSVRTIKQGYLSHE"
     gene            complement(24577..25206)
                     /locus_tag="ACZPB4_03400"
     CDS             complement(24577..25206)
                     /locus_tag="ACZPB4_03400"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097301.1"
                     /translation="MRLIQSPAYEDWDTLEAFTLRFAEDQPVRPSSVAIPEGRAYVPP
                     SEYELDGVPLDRYGVMVTEGRDEIMRSPTVKMNLSRTVLNVDGRIYDAGKVVYNSKEV
                     TLKCCLIAGSMTAFWICYDALLHALIQPGERSLYVDYNVEEYPCYYKRTSGWKLESLR
                     GRVVVTFNLTLEFTVFRLGGTDYLLATEDGDLIVTEDGEYYIDLGTYEN"
     gene            complement(25503..25835)
                     /locus_tag="ACZPB4_03405"
     CDS             complement(25503..25835)
                     /locus_tag="ACZPB4_03405"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097302.1"
                     /translation="MWLFFSPQGREFCAENDFPSLDMFRGMAGHVMPYGVYVDSGHVD
                     VTNPGNIAVIGDTDAVITIDDNERVHKVILMHGGKARVVASDYAVILLVNIGGEVEIN
                     KDNTVVIL"
     gene            complement(25925..30010)
                     /locus_tag="ACZPB4_03410"
                     /pseudo
     CDS             complement(25925..30010)
                     /locus_tag="ACZPB4_03410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780371.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
     gene            30150..30638
                     /locus_tag="ACZPB4_03415"
     CDS             30150..30638
                     /locus_tag="ACZPB4_03415"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097303.1"
                     /translation="MEFEIIKIKQLSGKKAQIYSVILGQEDQSVFEQFLQNNYSEYPT
                     EIEDIVSKLKIMATKTGAAEHFFKLNEGKPGDGVCALFDSPDKKLRIYCIRFANVAIV
                     VGGGGYKPKNIRAYQESSSLKKEAETVVRISRIISEAIKNKDIHLDDNGFFLGNLKLK
                     EE"
     gene            30704..30937
                     /locus_tag="ACZPB4_03420"
     CDS             30704..30937
                     /locus_tag="ACZPB4_03420"
                     /inference="COORDINATES: protein motif:HMM:NF013540.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIR1097304.1"
                     /translation="MERRMMLAVKIAEGIKRKGLSQKEFAEKMCKRPSEISKWLRGDH
                     NFTTSTLFDIEDVLNIHLIDINEYSHAACPASI"
     gene            30945..31187
                     /locus_tag="ACZPB4_03425"
     CDS             30945..31187
                     /locus_tag="ACZPB4_03425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2442 domain-containing protein"
                     /protein_id="HIR1097305.1"
                     /translation="MNGIPPVGVTMINAHGILLFVGGKEYYLSYDRYPWFRNAKVSDV
                     LDVTMPDEDSLRWDAIDVDLEIDSIIHPERYPITFR"
     gene            complement(31332..31601)
                     /locus_tag="ACZPB4_03430"
     CDS             complement(31332..31601)
                     /locus_tag="ACZPB4_03430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097306.1"
                     /translation="MGRSEPVTQSSFMFLVLCNEAFGYTHERTLDSDLALVMSMLREH
                     GYLVNDRNKSLLVDDDESGDNHGEWVEVIDFDTGKKKRVRRMSPV"
     gene            complement(31580..32098)
                     /locus_tag="ACZPB4_03435"
     CDS             complement(31580..32098)
                     /locus_tag="ACZPB4_03435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097307.1"
                     /translation="MSVKRALQIESDVVTSRSVVIPFEFKPETIPAGKNVGDSIVITP
                     ITVRTGFRIRPLLLRIDKVDKDAIVAHKDVTFDSVLSELMAKYDELIFEIVCLGIHNK
                     KGDMPAWFREVLKDNCTWEDLYILLNAILFRLGCNPFSRTIIALEAVSPLSEEEIIAL
                     QENNETWVGRSR"
     gene            complement(32165..32692)
                     /locus_tag="ACZPB4_03440"
     CDS             complement(32165..32692)
                     /locus_tag="ACZPB4_03440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097308.1"
                     /translation="MERSLALDVAYLGVAEPGDGVAGTEFTQCVDVDTVTFNFSDAKE
                     LSFTSMGHEDPWAVVSRKGDPSSIEFTIPSPTSDEMKMFCGGTVSGDKWEAPLSTPSI
                     LKTIRLQSLPYQGKFTEYVFVKCSVFGKISQAPDKENCDLLLVKATIMTPVSAAGKQA
                     SPYSRAVKVVSEDTE"
     gene            complement(32697..33083)
                     /locus_tag="ACZPB4_03445"
     CDS             complement(32697..33083)
                     /locus_tag="ACZPB4_03445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005643090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097309.1"
                     /translation="MADQFDIVDIVYNAVEPASMGFILYKDQSGDGEKRNHITIRSLA
                     LNGKDYVNKGSININIFVKRPSKGVSDRQLMIETVRGVRFVLRDIKPPLGMYWKSRIV
                     WSEPMGEAKDGFDCTNIRLEVITELD"
     gene            complement(33086..33565)
                     /locus_tag="ACZPB4_03450"
     CDS             complement(33086..33565)
                     /locus_tag="ACZPB4_03450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005643088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HIR1097310.1"
                     /translation="MARKGGLTPMWSDREVGRWFDYYVDRAEERIYKLLQRAGEEFVK
                     IARKKGNYQNHTGNLRSSIGYVIVKDGDILTENYEQSTEGTDKQTGIREAKRLVSELI
                     PLYKRGWVLIGVAAMPYAKYVEAIENLDVISVATEHAEDWIKKQSRTLFDKLAEKGY"
     gene            complement(33569..33868)
                     /locus_tag="ACZPB4_03455"
     CDS             complement(33569..33868)
                     /locus_tag="ACZPB4_03455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097311.1"
                     /translation="MVKRYSHTAIVTIQTCQLVKGELVAGKPTEIEVTGQYYPSNSGQ
                     QLKRNVDGREFIVHGEFSTKARPVENAKHIRIDSIALDVDIISWEPFQTHSVIYV"
     gene            complement(33862..34200)
                     /locus_tag="ACZPB4_03460"
     CDS             complement(33862..34200)
                     /locus_tag="ACZPB4_03460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097312.1"
                     /translation="MAKTIRDTILAYPGLADCEDFLDNVVLPGRGFEGTEDSKTIDIQ
                     KQKLVAADLYSMVGGLPDFTENKLSITYPRAWYDATAKRLYREGGEPEKAELIGNKIE
                     VPKGRARNRW"
     gene            complement(34206..35390)
                     /locus_tag="ACZPB4_03465"
     CDS             complement(34206..35390)
                     /locus_tag="ACZPB4_03465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major capsid protein"
                     /protein_id="HIR1097313.1"
                     /translation="MERSLIKQVNKKNMAARLNTRHVKPVVFPNFFGVKRKTSLKWET
                     LTGEKGAPVMADVISFDASAPQKTREVISKLSGDIPKTAVKRGMNESDYNEYKQLERD
                     AQGDADQLALLNLAFKDQDFVYNSVRARFEWWCMQLMSRAGFHLSAKNNGGVVTAEFV
                     GCGMPKKNQRKSTTDWSNATTANGLQDIEDTVVAASAEGVTIRYVVMHVADFSLLKKQ
                     KSTFDTLKAWVNSSSKILVTKNLINEYLAEQEIPVKIITVNPAVRIEDRAHRRKTINP
                     WERKRVCFLEDLKVGDIQHGPIAAESSATLQKIALMVKQDWILVTKWSELEPFKEWTK
                     AEANAIPVVNDPDAMFIMKVDGKDWNASEDTEGTDDIPATFLGETIEPEDQTIQDTEN
                     GE"
     gene            complement(35409..36017)
                     /locus_tag="ACZPB4_03470"
     CDS             complement(35409..36017)
                     /locus_tag="ACZPB4_03470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097314.1"
                     /translation="MYRKREREFQYPPGIEKIIEDVIGGGTIDRRDLRNALFNGKSLD
                     ELPPIVIVVKDPETGLYHVLKTALVSEAAAADATAYKVAKNHLFGVGDFVTIGGALTG
                     ASDKITAIDKSNAEFDTITLEATIGAAAKGQVLVQAKDKQAAKAAKLPYDGELVVTMN
                     KVDLTVANQQSGLLVRGTVNESCMPFPVDKGLKALMSFIRFV"
     gene            complement(36038..36724)
                     /locus_tag="ACZPB4_03475"
     CDS             complement(36038..36724)
                     /locus_tag="ACZPB4_03475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097315.1"
                     /translation="MTILDLIKAACKTKGVPEKYAERIQKTFKIEKAEGMEAFVDLFK
                     DNILPAIQEAENEAKTTAETAAVAAYEAKHGLKDGKPVEDPDKNKKTEEELLKDLSPE
                     LKAYLESMRKSVDDMAKKVGDSITNSANEAKKETVRKQLKDAGLPDNWLGRVDLASET
                     SIEDQIKALSEEFTGIQQKAIDDAVARGDYAPGSVNLPERSEADWAKLMDQDADKSAN
                     NPGVVNLGIE"
     gene            complement(36947..37138)
                     /locus_tag="ACZPB4_03480"
     CDS             complement(36947..37138)
                     /locus_tag="ACZPB4_03480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6722 family protein"
                     /protein_id="HIR1097316.1"
                     /translation="MWKEKLGNYLIDVSKYIFTGVVVASLFKDMEDNKWLIYGLGFTS
                     SILALIAGLVLTNKKKEDK"
     gene            37426..37662
                     /locus_tag="ACZPB4_03485"
     CDS             37426..37662
                     /locus_tag="ACZPB4_03485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097317.1"
                     /translation="MSINSNKSNAANNSNGKRTAQPSEMGKYSTPELQAAFNSGREIG
                     RTEGMLYYIKHASENMQKEAEKLSAKLQMQRAKV"
     gene            37830..38381
                     /locus_tag="ACZPB4_03490"
     CDS             37830..38381
                     /locus_tag="ACZPB4_03490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor N-terminal domain-containing
                     protein"
                     /protein_id="HIR1097318.1"
                     /translation="MKNSSFNAKEIAKVNNVAIMASNDPRQLVPIKPICDALGIDAKA
                     QRNRIDRDEILNSTGVIMTSVAADGKEREMYCIPLRYVFGWLFSIDTNRVDEEARPSV
                     IKYKMQCYDVLYDHFSSYASFVNQKQKRQAEDWARIQILKKEFHEAKNKLAKATKQMN
                     MTVDYSFEQWKANGKQLILDFDD"
     gene            complement(38489..39793)
                     /locus_tag="ACZPB4_03495"
     CDS             complement(38489..39793)
                     /locus_tag="ACZPB4_03495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPD3 domain-containing protein"
                     /protein_id="HIR1097319.1"
                     /translation="MKELSFHERQFLQCLFRQQGSIKYSFDEFVRRIGPLLAKWSDYG
                     GDRVWIGNATIEKQIERLLDDLHTQLVSNISNTVTDVWNLGNRKADELVTGYIKDMAI
                     SSTLKDKMFSRSADALNTLLKRKDEFGKTISSRVWDITDGAMDNLEHYLSSGLSSGRP
                     AALISQDIRQLLNEPNRRFRRVRDANGKLVPSQPMKDYHPGQGVYRSSYKNALRLAAT
                     ETNKAFRTADYERWQNMDFVTGIEVERSPSNHGLCPVCDAKAGQYSKDFKFTGWHPFC
                     ICISTPIMMDHEEFAEWLLSDRKVEKDSISIQYSKDRAKELQNWAKQSLLNSSFSHKD
                     FPIQVKMTGKSIKEFLNQPHKFKKEKNELIKNIGAVFAGSDYKGYTEYHKDNPMIKYS
                     HVFEIDLKGEKSWIIVREDITGKAVLYSISDSDKVLTGIKKK"
     gene            complement(39790..41259)
                     /locus_tag="ACZPB4_03500"
     CDS             complement(39790..41259)
                     /locus_tag="ACZPB4_03500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HIR1097320.1"
                     /translation="MPSISEILANEDFGQVVSTLCVDTIEYREPREYYREYHGERRRR
                     KTSVGWREPKRLAVYSETLKDKNGAPLRLEDKIVDVARIVTNFPKKVVRTSVAFLFGG
                     QMTITGTDQNDGFQEFKRVWERRLRMQSVLKSFARKVLSESKAALVFYPCTFKGLDGK
                     LITELKVKTLSVPRNENTFSEFYPHFDDNDDMDAFIHRYQVNSNGMIRNSCTIWMADK
                     IITAIDEMGGWAIKEVPNLFGKIPVVYADVFQPEWDEVAGIMDAREMRLSRMADTNDY
                     FAEPILKTYGNSDLPSKETTGKDINFPITVDEVSGKEYHGDADYLTWTGSQPSVDKEL
                     EETKNEQFAGTSTPDLSFDNLKGIGNLSGVARKFMLMDATIKASENMETFGPVVQRCV
                     SVVLAGICNITNIKYRPQLVNNLIDVEFGSILPEDLAETLQTLSVANGGKPINAQRTV
                     TAHSPLTEDLDEEMKLMEEEEDTAAQRNNMIGLTMGYGE"
     gene            complement(41445..42890)
                     /gene="terL"
                     /locus_tag="ACZPB4_03505"
     CDS             complement(41445..42890)
                     /gene="terL"
                     /locus_tag="ACZPB4_03505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit"
                     /protein_id="HIR1097321.1"
                     /translation="MAKRSKRDILIRQAKAATILRKREARNDFWAYCLYHDPKLFAKR
                     LFLKKVADAFTRVYESYVSGVIRRLAVSMPPRAGKSYISSLFISWMLGHFPEESVMRN
                     CCSDTLYNKLSYDTRDIVRSSRFKEIFPDIQLRGDKQNVHGWSLEAARQVSYFGAGVG
                     GTVIGFGASMLAMTDDLYKSLEDALSDTNNEKVWSWKQGTHDSRIEGNCCSIDIGTRW
                     SATDVLGRMEEMGKYDEIIRIAALDENDCSFCEDVHTTEYYHELREETDDSIWCAEYM
                     QEPIEAIGLLFPKSELNRFKLADIEGKQPDGVIGATDVADEGDDDFCAPIAKVFGTKY
                     FITDVLFTKDNVEITEPKLVSLILDTRCDNMRIESNNGGRLFALNVRKAVKAKNEKCI
                     IQAKPTMANKDTRILLKSGWIKKHCYFLEESEYKKGSDYDRFMKALTSYKKEGGNKHD
                     DAPDGMTILAENVEFIGLCKANSVRRVARGR"
     gene            complement(42874..43362)
                     /locus_tag="ACZPB4_03510"
     CDS             complement(42874..43362)
                     /locus_tag="ACZPB4_03510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007558041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIR1097322.1"
                     /translation="MTEKNEVKKKSRGRKSEYREEYAEQALKLCLLGATDKEIAEFFS
                     VSEQTLNSWKKKFPQFLESLKKGKAVADANVASRLYSRAIGYDAKATKFATNEGRITD
                     KVEYIEHYPPDTTAAIFWLKNRQPAKWRDKKEVENLVKLGDELESMSDEELEAIIRGE
                     KE"
     gene            complement(43365..43958)
                     /gene="folE"
                     /locus_tag="ACZPB4_03515"
     CDS             complement(43365..43958)
                     /gene="folE"
                     /locus_tag="ACZPB4_03515"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016661665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003934 - GTP cyclohydrolase I activity
                     [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0042559 - pteridine-containing compound
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0046654 - tetrahydrofolate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I"
                     /protein_id="HIR1097323.1"
                     /translation="MEVKLTNTQDIECAIRTILSFIGEDPCREGLRGTPDRIIRMWGE
                     IFRGYDLSQVPKITVFPNGVDGLSCDSVIADSGGFYSMCEHHMMPFFGKYWFAYIPNP
                     KGKILGISKVGRVVDYCAARLQVQERLAKDIIVMLQEALGSEYPPLAMGIVLEGEHLC
                     KSMRGVKKEGKMRSSFYFDNGSLPELRAELSRFVSFG"
     gene            complement(43913..44458)
                     /locus_tag="ACZPB4_03520"
     CDS             complement(43913..44458)
                     /locus_tag="ACZPB4_03520"
                     /EC_number="4.3.99.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005835838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016840 - carbon-nitrogen lyase activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="7-carboxy-7-deazaguanine synthase QueE"
                     /protein_id="HIR1097324.1"
                     /translation="MKKINEIFYSIQGEGYFTGTPAVFVRFSGCNLRCPFCDTEHKEG
                     KMLSDDEIIAEIRRYPALHVVLTGGEPCMQVTYDLVDKIKATGRFVQIETNGTLVPPV
                     NIDWITCSPKEGGKTVVINPNELKVVYTGQDMSQYDKYSAGVYYLQPCSGRNTKEVIN
                     YIKEYPKWKLSLQTHKILNVR"
     gene            complement(44442..44777)
                     /gene="queD"
                     /locus_tag="ACZPB4_03525"
     CDS             complement(44442..44777)
                     /gene="queD"
                     /locus_tag="ACZPB4_03525"
                     /EC_number="4.1.2.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007558046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0008616 - tRNA queuosine(34) biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-carboxytetrahydropterin synthase QueD"
                     /protein_id="HIR1097325.1"
                     /translation="MYTVRKRLEISASHRLSLSYASKCENLHGHNWIVIVWCRSKQLN
                     PDGMVVDFAHVKRMIQEKLDHKNLNEVLSFNPTAENIAKWICDQIPQCFKVMVQESEN
                     NIAWYEEDK"
     gene            complement(44785..45486)
                     /locus_tag="ACZPB4_03530"
     CDS             complement(44785..45486)
                     /locus_tag="ACZPB4_03530"
                     /EC_number="6.3.4.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-cyano-7-deazaguanine synthase"
                     /protein_id="HIR1097326.1"
                     /translation="MRNDTYNKKVLLYSGGMDSWLIDKLWKPDIRLYVDMNTRYSKEE
                     MKRLPDDTIIERLDLSKWEREDKIIPLRNMYLIGIATNYGDEICLGATAGDRVLDKSP
                     VFAELYEDLLGYLYQKQHWTEKRTIKINLDYKAYTKTELLKQYIAQGGNISEAFSSSF
                     SCYAPVDGHECWNCKPCFRKFIAFALNGYPFSMDVIGRNISYIKHEILPLIESGEYGR
                     KREEEEIRQVLTLYR"
     gene            complement(45467..46210)
                     /locus_tag="ACZPB4_03535"
     CDS             complement(45467..46210)
                     /locus_tag="ACZPB4_03535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016661667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097327.1"
                     /translation="MILYLAGYKPCAKRWNLDTKDIYLLSSFWEHKSGHYGGYVCQEK
                     HILDSGAFSAFSGKNNSFDWDGYVKKYADFVLKNNIQRFFELDIDVVVGLEKVEYYRK
                     YLEDRTGRRPIPVWHASRGKDYFIRMCEDYPYVAIGTTSAMEEGRRIRGNPMILKWFI
                     DQAHSVGTRIHGLGFTDTIFLPFLKFDSVDSTTWLSGSRFGQIYFFNGKQMIYRNPPQ
                     GMRAKNHDLSNRHNFNEWIKFQRYAERYL"
     gene            complement(46207..46686)
                     /locus_tag="ACZPB4_03540"
     CDS             complement(46207..46686)
                     /locus_tag="ACZPB4_03540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB N-terminal domain-containing protein"
                     /protein_id="HIR1097328.1"
                     /translation="MTELKYDPRNYRIHTDKNKRLIKKSLEDCGTGRSILLDKNDVII
                     AGNGVYEQALELGLKVRIVESDGNELIAIRRTDLSTEDEKRKLLALADNHTSDTSMFD
                     FAAVVEDFDIDELGDWELELPFDDIPTDVDRFFEGADKVENKRKTMVCPHCGKEIEL"
     gene            complement(46718..47197)
                     /locus_tag="ACZPB4_03545"
     CDS             complement(46718..47197)
                     /locus_tag="ACZPB4_03545"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="VRR-NUC domain-containing protein"
                     /protein_id="HIR1097329.1"
                     /translation="MSIKEHSCIICNKRTVSVIKTEEGHICYNCYSDKKNPSKQKQHH
                     DNEEARIQSEFFNKVPLFFPNLPDRLLFAVPNGGSRHKIEAANMKRQGVKRGVADVIL
                     QIPKKGYASLCLEFKTSTGKQSPDQKEYQRQVEMAGSKYVIVRSVEQAIRELQLYLC"
     gene            complement(47553..48209)
                     /locus_tag="ACZPB4_03550"
     CDS             complement(47553..48209)
                     /locus_tag="ACZPB4_03550"
                     /inference="COORDINATES: protein motif:HMM:NF020376.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIRAN domain-containing protein"
                     /protein_id="HIR1097330.1"
                     /translation="MNRCFDKIYLSWRVGKGSPRIMVGILEEKDSGVVFQYLKEGVER
                     ARQYGFRGYPGLALEQMVHEKNVLDLFSKRIINFERTDTKWLLEFWEVDQSLKEDTLY
                     MLAMTQGKMQTDSFEFLASFIPDNGLSFVTDIAAITHYGFDLDTLHEGDYLTFKTEPD
                     NPKDPKAVEVYFEDKKIGYIKKGHNEVFFGTQPDRLTMQVKAITNTPSFKELYVKISS
                     "
     gene            complement(48190..49227)
                     /locus_tag="ACZPB4_03555"
     CDS             complement(48190..49227)
                     /locus_tag="ACZPB4_03555"
                     /inference="COORDINATES: protein motif:HMM:NF019421.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HipA domain-containing protein"
                     /protein_id="HIR1097331.1"
                     /translation="MAKYIDISNWKTQVHVHTGGTRDKFIAISPDDDKKYYFKTSINK
                     GFKNYKYEFWSEVIASELGRSLGFNVLIYDVASFNDKIGCLSKSIIEEDKEEHHDGYR
                     YIVQKYPDFSENFKKAHSYQRIIGALKNVQLENLKRDVIEMIIFDAIIGNTDRHSENW
                     ALVVKKSEYFEVFDRFCEHYERSNWIVKWMVFCRFFVKFKMTIQSLKKIITRQKTTFS
                     TIYDSGSSLARELSDEKVCELLADEQKMDHFIGKGKPDIRWNNENLNHIELVNTIALD
                     DYEIVHQVLERVKLLYNKQMLQDLVFHIDKDVPENFSGHKIPEERKRFIVKYIDSRIS
                     KILHSHEQMFR"
     gene            complement(49408..49776)
                     /locus_tag="ACZPB4_03560"
     CDS             complement(49408..49776)
                     /locus_tag="ACZPB4_03560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010803638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097332.1"
                     /translation="MVNIIIDLVMFFNVGKTMKDTQAAQTADLIIEEFYFFKPDDFKL
                     CFNRAKKGLYGKVYDRIDGAVILEWLGRYEKERGSMAMDDSINNSKSWDIPEGDRTSR
                     TLEQAYHEFRKYDFERKYKV"
     gene            complement(49853..50758)
                     /locus_tag="ACZPB4_03565"
     CDS             complement(49853..50758)
                     /locus_tag="ACZPB4_03565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097333.1"
                     /translation="MPRIRTIVPEFWEDERFSNVSLPACLLYIGMKNFADDSGVILAN
                     ETIIKSKVFPAREDIRKQQISGWLQELIENSILVPFTFENKSYYVMDFSSERIDKPQK
                     SKIPAEVIENVLSGKNRSNPGTFENIPEQSGTIENPPAGKESKGEDWKGEEGYTRVGT
                     RNPDPEPEKPKNENFEKFKQWIAANAPSVAKLKEPFTEEQFERIKRDFPLQLIQDTLV
                     SMHNYRELLKKYVSANLTFRKWAKRDLEKYQNGQATSNTASGQHRPDNRSLAGRTNAE
                     NNRASLEHLRSLADAILQSPTPENG"
     gene            complement(50761..52080)
                     /locus_tag="ACZPB4_03570"
     CDS             complement(50761..52080)
                     /locus_tag="ACZPB4_03570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfJ domain-containing protein"
                     /protein_id="HIR1097334.1"
                     /translation="MKPRTRLEKLVAGLSEKLPAITKAQEEWAKEHVFDHVAYKCKNE
                     LWCSECGEIWVNTGNSKLGDKTECPYCHHQLDVKVSRKQKNHEEAYMSILQVRGGFQV
                     IRHILCWKNARRGTSPVYYDFTEVVQEWIREDGKRTIIARPINMGRNGFAYSSPLSIK
                     GEYGSNPYNYYGDLYAIFGELYPRKELLPELKKRGLNRLFPDVTPSKLIRDLLKGGND
                     AELCLKTGQISMLKHMYRNGFSQLRYKPSFNICNRNHYIIKDASLWEDYMSLLAYFGK
                     DLRNAHYVCPKNLKVAHDRLLAKKDAREAKLRQDRDRVEAIRRREKLMKDIAGFYERM
                     EKFFGMKITDGNIVICPLESITQFYQEGKAMHHCVYKLGYYNRPDRLILSAKDTGGKR
                     IETIEVNLKTLNIVQSRAVCNGVSEFHDQIVKLVKKNMNLIRQKMIA"
     gene            complement(52082..52483)
                     /locus_tag="ACZPB4_03575"
     CDS             complement(52082..52483)
                     /locus_tag="ACZPB4_03575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfK-like family protein"
                     /protein_id="HIR1097335.1"
                     /translation="MKEFKDTIQKYLQERAAEDLLFAPRLANPKKSIDECCRYILGEA
                     RKRGTSVVMSDTEVFGMAVHYYDEENIEVGKVPVGSSVSSSHKVELTEEEKNAARQAA
                     IKRLTEEQYRSLKKRPAKKKVDESVQQMSLF"
     gene            complement(52487..53599)
                     /gene="dnaN"
                     /locus_tag="ACZPB4_03580"
     CDS             complement(52487..53599)
                     /gene="dnaN"
                     /locus_tag="ACZPB4_03580"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HIR1097336.1"
                     /translation="MTISISKTALLSRLQLLAKIIPAKSSTPILCHFLFKTREGRLFI
                     TGSNSEGRITTSLECIFDEEISICVPTSLLEGLRNLPEQPIDIIINKDTREIRIKYHG
                     GKFEVVGYDPSTYPGKRSIEVLDSVSLSAEDLFNGISKVINLAGNDDIRPVLSSVFIE
                     TEPETVCFVGADGHGMGFLRKGNDRQVGKISVIISRPIASVLKAILPASSDNMEMRVG
                     ADWSDVILNDYEISFRNVEGRYPNWKAVVPKANKLELLVDTGQLIGAIKRTSVFSNKA
                     SCLIVLRIIRDKLTVFAQDIDFSTSAEETLEVDFNGNEFSIGIKGSLLLEILSCIDDG
                     RTRLSFSEPSRAILITPENQSGNEELTYLLMPMTIP"
     gene            complement(53747..54967)
                     /locus_tag="ACZPB4_03585"
     CDS             complement(53747..54967)
                     /locus_tag="ACZPB4_03585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0009037 - tyrosine-based site-specific
                     recombinase activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HIR1097337.1"
                     /translation="MAYFKICVRAKRKDNTYPVYIRVTHHGQVGYIKTDKVCKAKSVR
                     KGEVIDNYIIKDISILIDGYMSRLNREDIQCWDIRKILDFLRRDSSAPSFSEFCEGFT
                     SKMDNEGRESTSINYKLALRRLEEYMGKDDILFSDLTSSIFKEWIDSMKDSLYKKHGY
                     PKRIKTMFMAGCERYNNYDTGEMLIRNNPFRGVRVPRPTVPEKRALDIRTVRDFFAVS
                     AEYGSRADRARDVCEIVFCLAGINTADLYYMEKENLRDGKMCYCRRKTTNRRDDKAYI
                     EIAVPDRLSHLLEKYAGEKRLFNFCETYGSSKNFNKCINEGISDITRKNDLPHISVYS
                     FRHSWATFAQNDFDASLDLVGFCLNHASSHRVTSGYVKTDFSVIDRLNAKILDYVFEE
                     KNEKKMEIICGLKK"
     gene            complement(55101..55187)
                     /locus_tag="ACZPB4_03590"
     tRNA            complement(55101..55187)
                     /locus_tag="ACZPB4_03590"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(55151..55153),aa:Ser,seq:cga)
BASE COUNT        14713 a        14121 c        11174 g        15187 t
ORIGIN      
        1 ttttctttca taatctacaa tttaatagtt tagttatcat ttttttcact cacaggcaaa
       61 gacatcacat atttcaaaag ttccggtttc ttctccgacg tacaatttga tataatttgg
      121 agatataaat caacgtcttc tttacttatt ggagatacat ataacttttc ggattttatg
      181 cccaaaatgt aactcacaag cccatctata ggagttttat cagacgctgc attcaacaac
      241 tttaaagatt tcatgaaaaa agccaaagca tctttcccat gtccactatt aaattgacga
      301 ataccttcta actgttgaaa caatgcactt acagtcagat cataatcgct aattttgtcg
      361 tgaattatat tttcattctc tttttttagt ttactaatag tttcattaaa gtcttctatt
      421 tgtcttttga cctcaaacac attcagtatt tgccaaccta ttaatattgt aactaatagg
      481 ctttgtactc caagcacaaa gccccaataa tccttaaaat caataggagc aactcgatat
      541 gacaacatta gcgctataac agacatcacc aatgccaata ttgaaaccca acaattcctc
      601 atatctatga tttaattttt actaataaaa gctaatacag aaatcacaaa agccgcaata
      661 gaaaacgcaa ccataatata gttatttaac atagctctaa cctctgtttc aataagtccg
      721 gtcctaagca cacagagacc ttcttctgta atcgatatag atcgcttatt gtcatcagat
      781 cttttcaacc atttttccct aattagatgt tcttctataa tatccctatc agtcggatca
      841 cttgtgaaag atttaatatt attataataa cgagctctta caaaacgtcc cacttttcta
      901 tctttcatag catattgagt aagtaatatt actctttgtt cgccaaaata tgacatcatc
      961 gatattctta agattatcca tagtctacaa tttatagttc aattatttcc ttgtgaaagc
     1021 ataagcctac attaatatcc tttacacgaa gaattaccat aatcacatta tcatcacttt
     1081 cttatcaatc ctttaatcac agatatacaa attaattatt aaaagagtta tttactttga
     1141 ataagcaatg aattaagaat cgataaaaca tctttgcttg caaaaatttc acttagcttt
     1201 ttcatcaaat attcttcaga atctattgta taataacaat tattcaacac attattcaat
     1261 tgcagcggat acatatttaa caaataatga gttatagata atatttcaaa tctgtaatca
     1321 ttaaaaaaag gcgcacgtat atataggaca tgacctattg gtttatttaa atcgggattt
     1381 gatacagatg gacatttcaa tgcgtgatac aacaaataat cattaggttc acatgtgtga
     1441 acctcaccta tcaaaacacc tgatgttttt ttactcaaaa aatcagcttg cgtcaacaaa
     1501 atttctttag gagtcattga actttcaaac tcaaaatcag gccatagatc ttccatatat
     1561 ttatattttt aaattaaact taattggtaa atgatccgat aaggatttat ctaccaaatt
     1621 attactagtt aatagatcta atttattggc agatgttact atcttcaaat cagattcgtc
     1681 aaaactattt atcatatctg gacgtattag aacttggtca tataaatgcc aataataatt
     1741 aatatgtcca ccagagttat aatacattgt tccagaaaca tctcctctcc ctaaatcacc
     1801 tagaaacccc cacataggat tatagaaaaa agaaaatttc tcaccttcaa ttatacattc
     1861 ctttttattt gcaatatttt tctccattac agcatgtaat ccttgagcct ttattattcc
     1921 tttatcaaaa ggattcatat taaaatcacc acaacaaata gttctttggt gtcccaattt
     1981 agattctatg tcctctataa atcgtcttag gctttcggcc ttttctgata actcttcatc
     2041 tgagttattt attttactat gtaaatgaca tattactaaa gttatgttcc cttgtagtaa
     2101 agggctgtat aattctttaa cgctgattct aggtttatcc tctttgttag taattttaca
     2161 atgcctataa tataccatta ctttttgata atttactatt ggaactaaat acttaaaaat
     2221 atcactatta ttagcgttta gactcttaag taaatcaagc tgcttatttt ctggacattc
     2281 cgcaatcatt aagacatcta tattctcggc ttctgcaatt gatgcaattg atgagaacaa
     2341 agattcattt ttatgtatat tccaaaaaag gaatcgcata tcaatattta cttaatctgt
     2401 tgcttcaatt gttcaatctc atactcaagt aacgcaatct cctctttcaa aatctgattt
     2461 tcttttctct cgcgttcgta ctgatgacga agtattgcaa ttgttttgtc tttgtccatt
     2521 aaatcttcca tatctatatc atttctattt attcttaatc tccaacaccc tatccccaaa
     2581 agccaacttt atcacatcag ctttcacatc actatcttcc aactctaatt gcaatatcac
     2641 ttttggagtc gtcaaaacct tttctccagc agattgctcc ggcacatacc gctctggcca
     2701 agtgaacagg tctgttatgg aaattcccaa gcaacttgcg atattctcaa tttctgaaat
     2761 tttcaaatca cgattacctt ttttcataac agaaatttga gactcatcaa tacccatagc
     2821 atcagccaac gttcgttgtt tgataccctt ttgagccatt atcttaaata tgttatctat
     2881 tacattcata tttatgaagt tacgcacaat attcgcacag ttacttgcga aaaacaaaag
     2941 tttttattta gattttcgca aatattcttg cgtatttcac aagtttattc catatttgca
     3001 cctgtaaaga ttaatagtag ttgcgaaaat ataaagtaca gaacatatat aataatgtaa
     3061 ggaggcaaaa atggaaaaat taaacctaca aggtcatgag actggcgctc gttcgttcag
     3121 agagatctac ttctccatgg acaacacgcc gcctaagaag gctttcatcc aaaagatagc
     3181 caccattacc aaacgatctg aatcggccgt cagatgttgg gtagcgggag tctaccaacc
     3241 ggatgcgtta gcccaagaag tgatagaaag agaacttggc attcctgcca gtgagttatt
     3301 cccaaaggaa gataaggtat gcgcgcaata gaattctata ccaccccctc cggcgaagta
     3361 actatcaaag agcagggaca gccggaacgc caactgaaag agtccgatac ggatttcatt
     3421 caaagtttcc ttgagatttt ggaagagttc tatacggagg cttatgcggc actccgcaag
     3481 tattacgccc gctacgacgg gaataaatgc taccgggatt tcttggctgt acgcaggttt
     3541 atcaaatgca acttcgggct gtacgataac atgatagacg tggatgagaa ctggaatttc
     3601 aaattcgagt ttgtcggctg ccctctacga ggagagtgtg acgggtttaa gaaaatctgt
     3661 gaaccgaagt tcaacagtac attatcagac agccagcttc gggtgatgga gctttgctac
     3721 tatggcaaga aagacgaaga gatcgcggaa acgcttttca tctcgtccca caccgtaaag
     3781 aaccaccgga agaacgtttt ccggaaactc tcgatacact ccatggcgga gttcatgcga
     3841 tacgcgaacg aaaagaatct atttaagggc gaataatcat gccaaccgaa aacacctatc
     3901 aaagcatacc ttctttacga aagatcgaga tcgaatacct tgcttggcaa atcacaagga
     3961 tgcaagcggg tatccgggaa tttatcgggc aaaaggaagc gcacctccgt ttcgggaggc
     4021 agaacgtgga aaaatgggtc tcggaaggta ggctacaacg ttacaagcga ccgggcaaaa
     4081 tcgagtacag gctggaaaac ctgtataagt gcgccctgaa tccatacgac tattaaatga
     4141 atcattaaca tagcaaggca ccttggcaag gcgttgcaaa aggaagttta cgatacccat
     4201 ccaactcgct atttcacgga cggtaaaccg cattgctaat aaatcattga cgtatgaaaa
     4261 cagattactg gaaactcgcc caagcggtga ggtggggatt ttacatcctt ttcggaacgc
     4321 tcgccatact tggaatcgtg gctatttgcc taggacattt cctgcatatc atcacgacgt
     4381 ccggatgtgc ggcaatggct tacatgatag ctaaacattg gtaactaata tttaaaaaca
     4441 taacatcatg tcgaatctaa ttcagatcaa agtagctgag ttgaatcagc tagacccgct
     4501 catgatagcg gaagataaca gggtagaaca aaagttcatc caaatgtata acgcaatctg
     4561 gggtaccgcc caaggagcgc aaatctacga gaaagagaaa ttcaacttcc ggaagatctt
     4621 acaagacaag ccggaactgc aaaaatgcac accgttatcc ctctatggat gctttttgga
     4681 tatagcggtc aacggcctgt cacttgaccc gacaggacga ccgcactgtt atattcttcc
     4741 ccgtagcacg aagaccggct ataaggataa caacggtagc gatatctacg aactacgtgc
     4801 ttatctctcc atcaccggat atggcgagtt agtcatgcgg caacgtgccg gacaagtccg
     4861 ttacgtggat aatcccgtgg tttgctatga gggcgatacc ttctcccccg ggttgatcga
     4921 cggcgtaaag accgtgacct accaagcggc atgcccccga aagtccaaca aggtgatagg
     4981 tggtttctta cgtatcgtac gctccgacgg taccgtggac tggcactgga tgatggaagg
     5041 cgatatcaag cgattggaag tgtacagctt taagaacaac cagaaatgga acccgcaaac
     5101 ccggcagaaa gaagggaagg ccaatgccct ttatacctct agcgaaggag gtattgatcc
     5161 gggattcttg gaaagcaagc ttatcaagca cgctttcgac ggatatccca aggtacgcac
     5221 gggacagttc tcctcattcg agacacagga ggaaccgcaa gagatcgact acggactgga
     5281 agaaacaacc gttatccagc ccaatcaagc cggacagcaa ccgcaagccc tccagcccca
     5341 atcggaaaat cctttacaag gattcggaga gcaaccgcaa gcggaaccga tacccgtatc
     5401 tggtataaca gcccaaatat cacaagaaga tgaagaagcc ggattttaag agttcaatat
     5461 caacattcaa aattttatcg acatggatac acagaataac aatttacctt tcaaggctaa
     5521 cgaggtcatt agcatcttac agacagcccc ggatattctc gcccgcaatg agccgtcggt
     5581 ctcagcttgc acgaacgcag ggaaaaccct cttggacacg attgagggaa atggaggtat
     5641 cggcacggac gagatcgaca ctgcggtaca agaatacctt gcgaagtcaa agaagaccgt
     5701 agagaacatg aacaaccgcc ggaagccgtt aacccaaatg ctaacggcca tatccaaacg
     5761 tttcacgaca ctagagggtt ccatagacgc caaatccaag ggaaccatcc cttatctgct
     5821 acagatggag cgtaacaaat acgccgccaa gaagctggaa gagcaaaaac gccgtgagga
     5881 agaggcccgg caaaaacagt tggcggagaa cgagaaagcc caataccggg ccgacataac
     5941 ggtcttgctt gataccacgt acgccgccta cgtcgagaag catatcaacg ccttgaacgg
     6001 gattttcaat cgtgcctccc tagccacgta tggggacgta tgccggcaga tcacgcaaac
     6061 aagcaccggt ttctcatgga cggatttcgt gaaaaacgtc gtggataaca aaacagacat
     6121 tctatatgga cggtgagacc cgcaaagcga tcaagaacga gatagccatc ctaaagaaaa
     6181 aagaatattc cgatcgatac gctttcgaga tcgagggact gaaacaatcc ttggtcgacc
     6241 gcctcccatc cctccggaaa caactggagg agcaagagga aattcgcaag accaacgcaa
     6301 tcgaggcggc acggctggag gaggagcgca aacggaaaga ggcggaagaa cgtcaaaagg
     6361 ccgaactgga acgcaagcgc aaggaagagg aagcgagagc caaggcggag gcagagaaag
     6421 ccaccgcgga agtacaggca gccttcgatt tcagtgccgc cagtatgtct cctaccccta
     6481 ccaaggcgaa gatcaagaaa aagatccaag tcaccaatcc acaaggattc atgcaggtat
     6541 accagatgtg gttcatgcgt gagggtatca acatgagcat ggaggatctt gagaagatcc
     6601 ataagaagat gatctcctat tgcgagaaaa cagccaataa ggacggtgag cgaatccagt
     6661 ccgcattcgt gaaatatgtc gatgatataa cggccaagtg atatgagaaa gctatatctg
     6721 tcctcatgga taaacttcgg gaaatacagg cgtacaccga gtaacctaaa aaagatcctc
     6781 gatacggaag agggccgcaa atggttccgg tggctgatgg ataacactta cgattttgaa
     6841 tttgacttcg cagtcattga atacttaaaa ctcaaggaaa aagatgcaag atacgtatta
     6901 ccaacggtct gaggtcagca actcagacct gacagaacta aagaacctcc tctatccccg
     6961 tacgcaatac ggggataagg agaaggcgtt caagttcggg agtctggtgg atgcgatgct
     7021 gacagaaccc gaacgggtaa gatatgacaa acatacggta gatgacgtat tgtattccgg
     7081 cgaagattgg gaactggcac aagccatgat caagtcactc cgtatggaag cccgacacga
     7141 tcccttattg gcgcaagtgc ttgctaaagc ggagacgcaa cggttcatgg taaacaaggg
     7201 gcaacgtttc caatacggca actttgaata tacgctcgac actcgttgca aatgggactg
     7261 gtggcttccc acattcggat tcggcggaga cttgaaaact accttcgcca gttcccagaa
     7321 acagtttgac gaggcgattg atttttttga ttgggatcgt tcccgtgcct ggtatatgga
     7381 tatcgccgga agccgtcaag atttcatcta tggtatctcc aagaagaacc aaaaagtgtt
     7441 caaggctttc atcagacgga acgatcctag ctaccggaaa gggaaagaga aatacgagga
     7501 actagccttc cggtggtgga tgctaataag ctaatagtat gaagagtcta gttttaatcc
     7561 taatcgactg gctaaagtgc aggctggcaa agaaatgccc tatatgcgga gcttccgtac
     7621 tcgtaaagaa attacagacg catacgggaa atacattcaa cgtatatcat tgcggcaact
     7681 gtggcaacga ttatatctta aaataaaaat catgaatctc aatatcacac cgacagacaa
     7741 gatatccaag gaactggccg ccatagatgc cttcctgaat atcacaatga gcgaagacgt
     7801 acaagaagct gtcctacgtg gaaacgacct tgccgtctat atcgcccgaa ccgggaagct
     7861 gttagcggac gcaaaatatc acctgaacgt gaaaaagaaa tcggaagtat tcgacacatt
     7921 acgggaaacc gcttcacggg ccggagcgac ctcaaaggcc gtaaacgcta tcatcgacag
     7981 cctgtgcaag gatgagcaat acctagtcga ctggtgtgat agattgaacc ggactgcgac
     8041 ccaccaattg gaatggtgtc gcacgataat tagcaaggcg aaagctgaaa tggccttagc
     8101 gcctcagagt tataacaatc ctaaatttta aaagagcatg gaagaattag taaaagagca
     8161 acccgtgtac gagatccaga aagtgaagat caagaacaac cagctcacgg cggagtatac
     8221 ggaaaagttc gtggaagcga actacaagaa caacatccta aaggaatcgg agcagtttat
     8281 ccaccccgat ctactgtacg cgttgaaccg gcttaagcca cacgtagtga aaatctgtga
     8341 gatgcacgag gctacattgg tcaatgtcgc caatccctcc gacgatgact tgaacgagaa
     8401 gctaaagaat atcatcgtca ccggatacag caaaggcggt aatgatgaat cagccggcgt
     8461 atcaatccaa gcgcaaaaac tcctgaagag cgggcagatc cttaacctct ccgtcccatt
     8521 caccaaatac gaggacgagt ctggcgacgg gtacctttac ggagccgagt tgaaagaggc
     8581 catcggtaga tgtagctacg aggtggacgc ttatctgttc gaaggtaaat atggcatcaa
     8641 gcaagaatcc ttcgatttcg ataccccgga ggaatcggat atcacgggcg agaaggaaga
     8701 gaagcctaag aaacggggac ggaagaaaaa agagcagatc aaggagatcg ccgaggaggt
     8761 gaaagccttc gacgagttcg cctaaccaat aataaaaaca accgttatgc aaatcacttt
     8821 acaaaacacg gaaaagggac aatgctacgc ggtaaggttt gacaggtacc gccagcaggt
     8881 cgttgacaag ctaaagacag ccgtcagcgt ccgctggtgg gacaagtcta ccggagcgtg
     8941 gatgatcccg gccaacaata agtgcaaggc ggaactagac cagctcacct attacgtgag
     9001 gcacttcgaa cccgtcaact ggggagggaa cgagtctaag accgacgagg acatagccta
     9061 tcaaataccg gacatgcccg agttggacga ggatcatggc ctaaagatac aaccttaccc
     9121 ctatcaactg caagggatcg cacgaggctt acaactaaaa cggtttatca atggggacga
     9181 catgggcctc ggcaagacat tagagagcat cgctaccatc aacaaagctg atgctttccc
     9241 ctgtctcgta atctgcccca atacggtcaa gatcaactgg caacgtgaat ggcacaagtt
     9301 cacggacaag aaagccatgg tattgaccga ttcggtacgg acctcatggc cattcttctg
     9361 gcaaacgggc atgaatcatg tgttcatcgt gaactacgag agcctacgga agtatttcgt
     9421 acgccgaatc aacaaatcgg agaaatggac gctgaaagac gtagagttcc ataatacgat
     9481 caagttgttc aagagcgtga tcattgacga atcccataag gtaaaatcaa cggctaccca
     9541 acaaagcaag ttttgcaaag gtatcaccgc cgggaaagag tggatcatcc tgttgaccgg
     9601 tacccctgtc gtaaacaagc ccaacgacct tatatgccaa ctcgctatca tggaccggat
     9661 gaatgatctc ggaggctgga aatatttcac gagccgctat tgctctgggc cgcacggggc
     9721 ctcgaacttg aaagagctca atttcatgct ctggaagcat tgtttcttcc ggagggaaaa
     9781 atccaaggta ctgactcaat tacccgacaa ggtacggcag attgtgacct gcgagatcac
     9841 caaccgcaag gaataccaag acgccgagcg tgacttggtg gattatctga gacgatataa
     9901 ggaggccgac gatgagaagg tacaaaaatc gctgaaaggc gaggtcatgg tacgaatcgg
     9961 catattgaag gacataacgg cccggggtaa gttgagagag gtgatcgatt tcgtgaagga
    10021 ttttcgggag aacggaaaga agatcatcct cttctgcaac ctgcatgaga tcgtagaccg
    10081 gctcctacag gcgtttccct cggcggtgtg tgtcaccgga cggcaagata tgcaacaaaa
    10141 gcaagcggcc atagacgctt tccaacggaa tcccaaaacg gacgtcatca tctgctccat
    10201 caaggctgcg gcggcgggta tcacgttgac agcgtcaagc aatgtcgctt ttatcgagct
    10261 accgtggaca tacgcagatt gcgaccaagc cgagagccgg gcgcatcgta tcggccaaaa
    10321 ggactccgtg aattgctatt acctgcttgg ccgcaagacc atcgaccaga aactctacag
    10381 gatcatcgag gagaaaaagc atataagcaa cgccgtgctt ggagcgaagg acaatataca
    10441 aacaaacatc gtcgatatga tggcccggat attcgacgag accgaggagg aggaataatc
    10501 atggcagagg aatacatagg gatcaaccgc ttgaaagaac gggaggacgc taataaatat
    10561 ccacgaagga aatgcgtaag atgtatccgt tatccatgct tctccggaca aggaataggt
    10621 acgcacgcca ttaatctcgc cgcttatgga tgtaaggatt ataaaagtca aacaagatta
    10681 aagaatatgt cgcacaatgt aaacaaagga ggttcagatg cttaaaatat cattgttaat
    10741 aatcggaatg atctcgctaa tattcattct cacgtctgga atatcgatcc agttcaagcc
    10801 attccatata tccctagctt atccatactt tggaacaggg atggtattga tagccattgg
    10861 tttcgccttg tgcttcggct cggcttacta tcatggaata tcaaatcatg aatataaaga
    10921 tggttacagc aaaggattca acgcaggtat tgaatacatt atcgattggg ctaagaataa
    10981 aaaagaaggc taaagataac atttttatag cgagagataa agactaacaa agagaataaa
    11041 taaaaaggca gcgcctcaca gcgccacccc attacaacct gcgacaaata tatcaaataa
    11101 agacaactat ggcaagtgag gcattgaata aatatattga gaaacgttac gacaggtggc
    11161 tggattacgc taagtatcac tgctcacttg ccggaatgag tagtgaagct attgacgtat
    11221 tgaacgaggt aatgtgtatg ctacttcaaa agcctctgga acacctctcc cggcttatgg
    11281 aagccaagca aggtaaatat accgaactag actggtatat cctgcaaatg ataaagctga
    11341 acgttacctc ggacacgtct ccctaccggc ataaatacaa gcctatcccg gtagatgaga
    11401 atgtggattg gcgaagactg aacattattg atgagcccga tgatagtatt gaccgtaccg
    11461 agtatatccg ggaacgtatg caggatatcc gggatatggt cgacctgtta gagttgtccg
    11521 aaaaagccaa acggatcttc gcttggaaat tcttcgccgg agagtctttc gccgattggc
    11581 cggggccgga aagccggaag gagttgtatg agacctataa aagtgttttc aatgcggtga
    11641 tggataagaa ggatgggagg ttactgtttt gatatttgta gactctaatt ttcaactaat
    11701 gcaaacatac gagtaaactg cggaagatga ttttcatccc tcgactatgc ggtttactcg
    11761 catatttaca tagaaggagg gttagaggtc actaacaaca gaagtttctt ttacccattc
    11821 tataacaaaa tacaacatac aaatgaaaag taaaaattgg ttcgtgtgta tatcgaacgg
    11881 gattacagtg tactttggga agccaacagg aagttgttat ccttattcaa atgggatagt
    11941 ctaaaataaa ttaggtcgac ctgttagact tatccgaaaa ggccaaacat ttgcaacctt
    12001 tattttccta aaagcaaaac gcaacgaacc cgtggaagag ggctttagcc cccggccatg
    12061 cgggtttgtc gcgtgtttgc gttaagtagg aaggttagag attttactta acggctgggg
    12121 gcttcttccg ccccttttat atgtaggtta aaatctatgc tatcatccag atctatttat
    12181 catatataca ttaatttact attaccggga caaatatagc aaaaagaaaa atgcccgaac
    12241 tcaatctagc ccaggcactc atttatttta attcgtgaaa taaagaatta gtaaaagtta
    12301 catctgacaa aaaaaattaa ttattttgcc actaacatct ggtgtcaaaa tgatcaagca
    12361 gttcattaaa gaacaaagtt atatccttac atacttgcaa aacaaagtct ttagttatac
    12421 atatttcggt tctttgataa taagagagga tacatgttac aagtgaagat attctattat
    12481 taaaaataat attgtaaaaa acctctggtt tgtctgtgat tccattatca tgtacaaaaa
    12541 catttcttat atctctgtat aaaagtatta ccttccactt ctcgttaaga gatgggatag
    12601 aatctatggt ctctcttcta aatgaaaaaa tatgcttaac ctcattcttt ataatattac
    12661 gagtaaattt tgtattatct tcttttccca ataacctaga gatttctctt ttagcaaaat
    12721 gcaaataata ttccaactgt gaaaacaagt atataagacc accattcaaa aatgcttttt
    12781 ctaaaaacat cacatcaatc gctttatctc cacacaattc atcttcactt tttgcgtcga
    12841 aaaaacgctt ttctgattga accaacgcca taccagaatt aacatagtca acaaaagatt
    12901 tatctacaga gtcccattgc cctcttattt gatagaattt acttatacgt ttagaactat
    12961 acataaatta tttgtattta aagtattcgt caaagttatt taagaatttg aaaccacaat
    13021 aactaatagc tcattttttc actaatagcc attagctaca aaaaaagccg ccttatcttc
    13081 ccagacaaga cggccgtgaa ctctactttc aacattaaat gtatgacaaa acctatttca
    13141 attctatata ctcactatat gttatctggc tataggggtt ccggcagaca atatcttgcc
    13201 ggatcgcctt tgtcccccac ttgataaacc agaaccgatg cggaaccctg tgtacagcct
    13261 ggtcgagcgt atcacgggat attatctttc cggagaacct acccatatct atacacccgg
    13321 acacatcgag atatggagta tgcagttcca gacacttcaa catgaccata ctgtcccgga
    13381 tcaccacgct atccttcacc ggtatattaa taggatacat cgtttccatc cctgtctccg
    13441 atacagattg caaccggctg atctttatat tgagattatc aatgatctta acttgatcgg
    13501 aaaaatactt ctcatattcc ttttttgtta acaggagtcg ttcgacactt gcggccgata
    13561 aactatcttt cgtccggtat agttctacct cttccattag gctacgctgg ttcccggaca
    13621 gacgcctaac ctccttcctc tcctgcctca acaaatagga aagggacgct attaccccaa
    13681 ccaagacaag tgagatacct agtataatca agaacctttt cataaacctt gtgtctttac
    13741 cgagcgttca accatgcgga ataacttctt catcgtctga acataatccg gagacgtagc
    13801 ataccgggaa ccaatgcaat cctgtagctt ttctgcaaac agatccggat tatcccgaaa
    13861 cggccaggca tctgcatacc cgggcttctt caatattgcc agatgatcag ccaagcaatc
    13921 ggcgagcgta ccatactgcc ggaacaaccg ttttacccta tacttataac ggccattacc
    13981 cagctcggtt acagacagga cacgttcggg caacttgaac gaaacgttat cacgattaaa
    14041 atactcggtt gtggtgacca gctcgaccgg ccccgtccaa ctactcccct tggtgatgcc
    14101 aaacaggtta ttcccgatcc cggattttcc ccaaccggac tccaatgcgg cctgtgccgt
    14161 cacgaatact ggactgattt cacctttaca tgcttcggga tatacccaag ctacaaattc
    14221 ttcaactgtc attctttttc ctccttatcc tttaattcta attttctccg ggggggtatc
    14281 ctcctgccac actcactatc cggacgatca cagcgattat tttccgcatc ttttagagca
    14341 agttcagcct catgcctttt atgtatctca tcaagtttgg ccgactgttc ctgtcggagt
    14401 tcgacataca aagcatcaat tttcaaatca cgttgggtaa tacgatcctc caaccagccg
    14461 acttgatttt tttcattggt aatctctaac gcatcggctg ccgcatcttc tttacgagcg
    14521 tctgtttttc gattcaccca cgcacggata ccccatttta tcccctcgac ccctcccata
    14581 gcacctatta cggctaatac tgtattcaaa tcaactccca tgactcgttt tcttttaata
    14641 tatacggggg cttttatttg cccgcccccg ataaggccta taatattttc tatctgttct
    14701 ccaactcttc caccctcttc tcaagtgcct tgaccttggc gtgaagctcc ttgataccgt
    14761 tgatcccgaa ggcggtcagc atctggatat aatcgactcc gtaataagaa tcatcatcgt
    14821 ccggtgtgat aagatggacg gcttcgggaa gcacctcacg cacggcttgc gccgacacgc
    14881 cgatgcgaag gatcttgtcc tcgtcctcct tcatcgtgta gtagaatgcg gagataccct
    14941 ccagcttatc cagcacgtcc gggatatcga agaagacgct cttcaggcgg atatcagacg
    15001 aggtcaaacc ttggtaattg gtgatataca catgggctgt gctcgccgcg tccttgttga
    15061 tatacaggtt ggctatattc ccgggactgt tccagccata gataccgttg ccgttatcga
    15121 tccgtacccc caagaacggg tatctcccgc ccggggcgtt aaatacgacc cccgtgccct
    15181 ccctgtacaa cactttctct acccccatgt cataaaaata ggggccgaat ccctcaaaga
    15241 agacacctcc ccatgagcta cggtctccga actggccggc gaactgcgtg gtcttcccga
    15301 tggtcagcat tctcgggaac gttatctggg tacgatccga gacggacgta tccacgatca
    15361 gtgacccgtt cgtgatggtg aagtttccga tccttgccaa gttcgcaaag atctcctcca
    15421 cgtcaatctc cgaggcagct atcttccgtg ccatcagcaa atcggtcgcc acgctggaga
    15481 agttcgcccc gaaggtgtcc caataggcgg tattggtcgg atgtttcccc ttgaaggtag
    15541 gctcgttatc atccacctta gccacataat acgagcgggt gccatcgcta ttcttgatcg
    15601 atacgatatc ggtaatcttg gagctggcgt tataggtagc gcttgagtcg taatcgccac
    15661 ggtaggtgca gcgggggcca cgatcgccac ggggaccggg atcgccgtct ttcccgtcct
    15721 ttcccggttt gccttcctct cccttgatct tggatacgct ccatgcgctc cataccccgt
    15781 ttctcttggt gctggtggcc atccagatcg tgtccgtact ttgggtgtcg ctccactggg
    15841 tattggtatt aggatgaccg tttggggccg acgggttcgc tacggatgag aactccacgt
    15901 cgaaatcggc cgtgtccgtc atttgcctcg gggtcgtcca cgccgcttgc tgtggatcct
    15961 tcccgtcgct cgtgaatatc ctcgtacttg cccatagtat agactctcca tcaggtactc
    16021 catcgctcca tcccgccgtg gtcggtaacg gggaggcgta cgagccgcca acggggacgg
    16081 cgggcgtggt ttgagatata cacttataca cgttaccatc gtaagatacc ttgtcgccgg
    16141 ggtaatagac ggacttatcg gagtaagcgc cccgatccac ctccggatag tcgatctcgc
    16201 cggagggcga ttggtagata ctgcctttca acacgagacc gtctcgctgg tcgtatgaga
    16261 ggaaagcgtt gtcatcaccg atccggaacg ccttggagag catgtcccaa tactgcgtac
    16321 cgtccatgtt aatgatcttg ttcagccgca tccatcccgg gcctatctcg ctgaagccgt
    16381 aaagcgtgga gaaactacgc tggccgtcca cctctgtact caaggctccg caaaggaggt
    16441 tgtaatacga gccgtcgtcc aagtccatcg gctccttgct caacaagaac gtgcccgccg
    16501 atcccgactt ggcgcagcgg gcgtacaggt acatggcctc cgtgtcatcc cccagatagg
    16561 gagacgtata ggccgccatg ttccagtact tatactcggt caccttgtgg gagggggcga
    16621 gagagtctat acccaacgtc atgtgctgca agatcccgga gggggtggca agcgtacgtc
    16681 tctgcccgtc atacgtgaag gcgtgatcca cctcggtgac cgtctgcccg tccgccgtgg
    16741 gaatacggtt gacgaaacgg aactgcaacg actcatgtcc caccaatacc gacatggtgc
    16801 gaagccacga catcgcctgc cccttgccgt aatccttgaa cgctttctcc agcatcccct
    16861 gcatctccac cgcatcacgc caacggcgaa gggtgaacga tacggcctgc ttgtgtcgtg
    16921 tctcgttcgt cacctcctcg ctctccagct tgcccagctc atcggacagg aaaccgccta
    16981 ccggcgtatt ggatagctca agctccgggc tgtggggcct gttgatgtaa tccctcaccc
    17041 cgatgatccg gatcaggata ccgtccggct ggaactgggg atcgctgaaa tcgacataac
    17101 cgccggggac cagcttggcg ccgatcgcca accaattctt cttggcccaa atcccgtcta
    17161 gctcgcctgt gaacgtgaat tgccgctcct cacgctcgta gaggtaacga acagcctccc
    17221 ggaacatgtc ccagctcgcc ccggtcttgg tggcgttgtc gcatacgtag gctgtgggaa
    17281 gggatatgtt aaagacggcg tacttgtctc ccacctccgg atacagggac gagttgggaa
    17341 gatccatgcc gtcctgctca gccggtacga tctcgaactt acgaccgtca tgtatgtact
    17401 ttacgtcgaa ctcacggccc gccagacggc ctgtctggaa aataaccgtc atggtctgac
    17461 cggcgattag gcaatcctcg aaattgaggt tggcgggaac cgatgagtca tagaagttgt
    17521 agaacgtgac atcgttcccg tccgtgtcct cgcccggctc cgtgtcggtc ttgctcaccg
    17581 taccgacccg ggatggatat atatcgctgg cgtcgtagct gtcctcatta taagaggaaa
    17641 ggggcctgtc cgcgcgagtg acatacatcc catccggatc ggtcttgtac cgtcggcctt
    17701 ggtactccag ctcctgtgac ttgggtaaca acaatgtctg gctgccatag gccgagtaat
    17761 cgatattccg ctcgccgcct tgcacgtaca atatctccac ggggaggttg tcgccttggt
    17821 tagcacgacc gacacccgga aggaaaccgt ttcccttgcc ataggatagc tttagaggag
    17881 cgtccttgta atactccacc ttgcggaggt tgatagtttt gcccacgatc tcgaactccg
    17941 tgtcgaactc ctcggccaaa cgccccaata cagcccagca tttctcatgg ttgaacgaca
    18001 acagtttctc cggggcctcg atcaccgtgc cgaccgtcca gccggagtca tagagattga
    18061 gattgtcaac caacaactcc acgaacatcc tcggagtggc cgtcatgacg aactttagct
    18121 tgtagggctt atcggagagc aacttgtatt tgtacttctt caggatctcc tcgttgccgc
    18181 cgaaggtgac ggtatagtcg aagaccctcg tgccctcctt cttgaaatcg gagggatacc
    18241 acagcgtgta cctttcccct tggtactcga tatacgctcc ggtgggcagc tccacgtgct
    18301 ccacgaggga ataacgcagc tccaccttct tcgcttgcgc tatcgcccgg taacgatagc
    18361 tgtcatcgtc caccgggatg tcaagtaaaa cgtctcctgc ctgattgtaa ataaccatcg
    18421 tttaaacagc gattaaatca agataaacac actcatatag gtagccagca aagcggcgat
    18481 ctccacccag aacataggct tcgtcctgta gaaatccgcg ataacgctat ctgacacgtg
    18541 ccgagtcatc atcacgatag tatagaccac gtaggccacc cataccagca ggcaccaagg
    18601 gcagttgaac atcacccata attgtgagcc cacaatacag catatggccc ctaactcgtg
    18661 gatatccccc tcgaaatcct ccttgaagtt gggggcggca ccgacaagga acatgccggc
    18721 gcaggcgagg aacgccagga actcggtgtc cggcctagat acctccaaga tagccggcat
    18781 caacaatccg gcggtaagcc acgtggtcgc catgaaccag ttcttatgct ccagcctgta
    18841 aaaggttgcc gagatcgaag ccagaacacc cttttgttta atacacactg ccgccgtgta
    18901 ggaggcaata atcaacattg aaataagtac taaataaatc atatcattac atttttaatt
    18961 attcctcata cgcccaatac cggataacga ccgtgccgtc accgcctctt gttgaagcat
    19021 tattgccaaa agtgcctcca gctccaccgc cgtagccacc accgcctttt cctcccacgt
    19081 aggaatcttg gcgacggtta aagctctctc cagatccttc ctcataatcg ctttcaccgc
    19141 catgatattc cttcatccta tgggaacaac cggttcctcc tccagcgttt ctcttaccgg
    19201 aaggctcacc gaaatccctg gtggtatgat tttggccttc cccccgatag acaccaccac
    19261 ccggtaaacc gtcagagcca ccattacctc cgtaaacgga agaggactcg tcctcgccac
    19321 ttccgccgga cccaccattc ccgccatgga gattaacctt aacgcatcta cctccctcag
    19381 ctcgatgtct atcatccata aattgggagt acccgccgtc gcccccgttt cctccggctc
    19441 caaccgtgac cgcaacgatt tgaccgggga agacggtaat ggcatcccca tcccgtccat
    19501 cattatatgt tcccatccag ctgcccgatg aaggtctcac gtatcccacg cccctgtaag
    19561 ttttcgtata tccgccaccg ccgccgccat aggagctgcc ggaagatatt tgcccggccc
    19621 ctgatccgcc acctacaagg aacacgtcaa cggaggtaca gccacgaggg actatccacg
    19681 tgtaattacc agccgggtaa aaccgcttga taaacaactt cttcctcttt cccatcatac
    19741 ttcttctcat atccggcctc cttccttatc aaagtcagag gccgtaacat atttataatg
    19801 aggcgattta ccccacccgt taacttttaa taacacatac tgtctcatcg ctttacctcc
    19861 tgtacgattg tgggcaagtc tttcaggtca ttcggataac ctgtaacggt cgtcagaatg
    19921 cagagataga tcacaccgta ttgttcataa tatttgtctt tctcgaatgc cataccctgc
    19981 acgtatggaa taggatcatc aagcgtgcct gcgtgctcag cttcaacgat cttatacagt
    20041 gaagcagttt ctatgcccgg tttccaatcg gcttgcagct tgtgcttttg tatcacttca
    20101 aacaaagtgt cgctttctcc ttccactact cgaagccgga agcctatttc aacttccttg
    20161 ccaaactccg catctttctc accccaaatg gggaataaga cctgcatctc caacgcttgg
    20221 ctggctgtga gagacacgct gttcatcatc gcacgggcaa aggtcactgc ctgcgcttcc
    20281 ggggatttag cgattgcctt atctgcttta gtttgcaagg ctgccgttgt tgtatggatc
    20341 atttcaggat agccttgcac cacgatagct tcgacctcct cggctgtttg ggcggcatcg
    20401 atacgggata gcaagctgtc tgtcaccttg ccgcattgct ccgaatagtc cgctatttcg
    20461 tcaagagcaa ccgttaagat attcgaggcg taaagatgac cgcctacttc gacttcttcc
    20521 tgccggccac acttatcctt cacttgcagg gtgttcgaga catatgcgtc ctgttcatca
    20581 atataataat gatggatgtc tttgtcgtag atttccttcc gcttagcgtc acgggcacgc
    20641 caaagcaact cttccggcgt gggttccgga tccggctcgg gggccatgtt ccaacactcc
    20701 aacggggtgg cctctggatg gtcgttatgg taccgctctt gctcggcgtt gagcaaaagg
    20761 taggcgccgt tatggtactg ctctatgtcc tcgctcacga ggtaggagcc aggaagctgc
    20821 tcttccacgt tccaaaatcg gatgtctcgc tgtatgtata gcatatcatt atctcctttt
    20881 tataaattaa actttcgccg cctcacatgc cccgcggcgg cgttgcgagg tataatcgtt
    20941 tgtccctgtc ttattccaac ggggcgaagg gacggacgta aaaaccaata ctcttagagt
    21001 tggcgtacac gtccttcctg ctccaagtta gtccccaagc agagtaaaag tcatattgtg
    21061 tggaagaata ataataagga gcttttatgg ctatacctcc tgtaatgaga ttcatacaag
    21121 catctatctc cgctttgtta ttaaacgctt ccaaccattc accacaggcc cccaaataac
    21181 cctttgcccc attcttgaac gtgtaattag cacaccaacc gactgcgtaa tcagtaccag
    21241 ccccataatg agagacgata gccgcagtgt tcgcctcgcc tttgtaatca tcaatggcga
    21301 tggtttcttc tgtagttgtc gttactcccg gaacttcctc gtatgccccg tatttactcc
    21361 aaggaagatt atcctcatca aggccctctg gcgcgatcac gaacctacag ttatccgtct
    21421 ttaaggctac gcccacagcg gaatcattcc aagcggcgtt ccactccgca cgggtatata
    21481 actttccatt cacgtgcagg atatacaccc cgttcgggta cttgtcgtaa tcgatcttac
    21541 cgcctcccat cactcttctt ctcatgtctt ctcctccttt ccgttaaacc cttaccacca
    21601 tcacgccgtg ttccttcttg atacttatcc cggccgtctt gccggcctcg atctccaagc
    21661 tcgtctcctc gctctgccag ccggaaccgt tagggatcgg ctgggtgatc ttggacgagg
    21721 tattgttctt gatcgacagg tagagctcct gcatctccgg cacgctcccc acgttggcga
    21781 aggcgatcgc cttgggcgtg gcggcggtat agacgtaacg caggttatac ggggtggcgg
    21841 gcagcttgcc gagatccgac acgtcggcgt actccttcaa ccttaacgag tccgccacct
    21901 tctgcctctc tgcgcttgtg taggagtcct taaaataagg gacaccacct acaataggac
    21961 aagccgtata acctgaggcg cttgtaacgg tactgccgtt cttgacaagg cctgtactgc
    22021 cattagcccc tacaacacca tatgtcgtat ttgtatccgt ccaaggcacg ttgacgaaca
    22081 tctttccgct accatccaat tccaccggat aattcttgcc attcttggca tatccgatca
    22141 tcaccaatcc aagggtagtg gcgctggcct tggcgtatgt ggtattcgtc ggaaccaccc
    22201 acgtaccatc tccacgaaga aacgatgttt gtttaccggc tcccggggcc gggaccaatc
    22261 cggccttacc cgcggcgttg gcggtagcgg cccccatgtt ggagtaggtg gtattggtgt
    22321 ccgtccaagg cacgttcaca tacatcttac cgccgctatc aagagatacc ggatagttct
    22381 taccattggt cgaatacccg gtcttgacaa gaccaagctt atcactagta gcttgagcgt
    22441 atgtagtgtt attatctgtc catggtacat taacgtaagc gttgccttgg gggtccagct
    22501 gtatcttgta gttcttaccc gagttggcgt aacccgtctt gataccaccc aacctctcgg
    22561 ccgtcgctga cgggagcgag tagttgttgg cgttctcggc cacccccgcc agtttctgtc
    22621 tctccgaggc ggtgtagtta ttatccgtat ggacgtactt ggcgtccttg accgtatggt
    22681 cgtcgttctg tagctgggag agcttggtag gtatcgcttt ctggacgttc gcgatattct
    22741 ggctaagccc ggcgagaata ccttgcaacg tctggctgtc ctccacgctg gagaggaaag
    22801 cgataatctc attaaacgac tcgatcgcat tggaggcgtt accggaaacg agcgtatcga
    22861 cttgtttctg taaagtggag agcgcggcct gtatctccgt atcgtcataa gtcgccccgt
    22921 cttttccctc ggctaccacg ccggtatcct catctcctat tttccaatgc ttggttgccg
    22981 gatcgatcga ggggacgggc gcagcggtcc ctttaaggtt aggcgtatca aactctcctt
    23041 ccgccgtcgt gatcgtcagg atgtaggtgg tcccatcgtt ttgcttgacc gttaccttta
    23101 cgtcctgcat gactgccggc aattccgcga acgcatgcac accatcggcc aacttcatgt
    23161 tgaatttacc gtttcccaaa cgttcaaata accagactga tggcggataa atggtcgtat
    23221 tatccatcca ttcggccgtc gttagctcga tctgctgata tatgaatgct cctttcttac
    23281 tcatggctta aatatccttg ttttatcgtt cgtactgagt cattgtaata gtttgctcct
    23341 gtcagataga cattaccggg taaggccgta ccgccgccag attcctgcca agatgctata
    23401 ccatccgcaa gatcataaag ccgatagaat acatattcgc cattctccaa cacacgcact
    23461 tcatcgccga tacggaagtt gatggttgta ccgtcgatat tgacatagct caatgtatca
    23521 gcggtcggta ccatgtccag cgtcggaatc tccggtttgt tcttgatgta gttcttattg
    23581 acagggtcgg aaatgttcca gtcgggttgt agcccactga cgactccctc ggccgcctct
    23641 gcggcggcgt tggcccgatc ggccgcgtca ttcgcgtctt gggtggcggc ctcggcgttt
    23701 gcaacggcta cggccgtatt ctcctgccgg gacgtttcct gttgctcacg catcccttcc
    23761 gccgtcttgc gggctcgctc tgccgtctca cgcaagccct ccgcggtttc cctaacggtc
    23821 tccgcctcgg cacgttcccg ttccgactgt acgcgtttcg actcctcctc ctttcgggcg
    23881 gcttcctctt caacacgttt cctctcgttc gtcatccgtt cctgttcggc ggagtcacgt
    23941 gatccctcgg cctttactct cgtctcctcc tgccgggtac gttcctgttc cgaccggtca
    24001 cgcagggcct cggccacgga tcggagtttc tcggtctcaa cccttttgct ttcttccgcc
    24061 acccgtccgt cctcttggcg ctgacggata gcctcagact ccgtacgagc ggtctcagac
    24121 tcaatacgct tggcttccgc cgtatcccgc cgggtctccg cctccacgcg cgattgttcg
    24181 gctgtcgccc gttcttgctc cgcagtctca cgcaagtcct ccgcctcgcc ccggaatgat
    24241 tcagcctcct tcctcgcgtt ctccgcctcg acacgcccct gctcggcttt aacacgcccg
    24301 gtttccgcct tggtaataac ctgattggtc gccagggccg tttcggcggc ggtctccgca
    24361 cggccggcgg ctgtattagc ggaagcggcc gccgtattag ccgccttggc ggcgtcacgg
    24421 gcgttggaga tctccgtgag catgttctcg taagccttct ggatcacctc gaggctcacc
    24481 ttcacgctgg tttgcgtacc gcttacaacc ttacaaccga tcgtgtacag accggtaagg
    24541 ctgtcggcca gcgtgagttc tgatattttc tttttcttag ttctcatatg ttcccaggtc
    24601 tatgtaatac tctccatcct ccgtgacgat aaggtcacca tcctccgtgg ccagcaggta
    24661 gtccgtcccg ccaaggcgga acaccgtgaa ctccagcgtg aggttgaatg tcaccaccac
    24721 acgcccacgg aggctctcaa gcttccatcc ggatgtcctc ttgtaatagc aggggtattc
    24781 ctccacgttg taatccacgt acaacgaacg ctcgcccggt tggatcaagg cgtggagcag
    24841 ggcgtcgtaa cagatccaga acgccgtcat tgagccggcg atcaggcagc atttaagcgt
    24901 gacttccttg ctattataca ccaccttgcc ggcatcgtag atcctaccgt caacattcaa
    24961 taccgtacgg gacaggttca tcttcaccgt aggggatctc atgatctcat ctcgcccctc
    25021 cgtcaccatt acgccgtatc gatccaaggg tacgccgtcc agctcgtact cggatggagg
    25081 aacatacgct ctaccctccg ggatcgctac ggacgagggt cttacgggct ggtcctcggc
    25141 gaaacgtaac gtgaaggcct ccaacgtgtc ccaatcctca tacgccgggc tctggatgag
    25201 tcgcaagctc cactccctgc ccagcgaggg gatacggatg cggtgatacc cgggcttcga
    25261 taggtgttcg acaagatcgc cggcggatct tccgtccacg ctgcggacga acgtgatgtt
    25321 gagctcccgt ggtttcatgg tgggcttttc caagtccggc tctatgccgt cctcgtccgg
    25381 ccagtcgttc ctgtccggct ccaccagctc ggggaaaggc aggaggccgt cgtaacctcc
    25441 ctccgtgatc catacgccga aatcggtgta ggcgtccttg ccgtctatgt ataactcacc
    25501 cctcataaga tcaccacggt attatccttg tttatctcaa cctctccccc gatattcacc
    25561 agcaggatca cggcgtagtc gctcgccacg accctagcct tgccgccgtg catgaggatc
    25621 accttgtgaa cacgctcgtt atcgtctatc gttatcaccg catccgtatc acctatcacg
    25681 gcgatattgc cgggattggt tacgtccacg tggccggagt caacgtacac cccgtagggc
    25741 atcacgtgac cggccatgcc acggaacatg tctaacgacg ggaaatcatt ctccgcgcaa
    25801 aactcacgcc cctgcgggct gaagaacagc cacacgaggc ttctccagtc cgtcaccccg
    25861 ttagaaccac tgcacgcccc gagcgagagg gccgatttga ttatgtcgtt aaccgtctcc
    25921 atcattatct tgatctcatt aatatcccct tgtcgttaat agtctttata ccggaggccg
    25981 ccgacttggt attggcctct atcttctcgg atagggcctc tatacgtccg gagatctcag
    26041 ctaccttggc cgtgttctcc gacaccttcc cggacaggtc cttgatcgcc tccacgttct
    26101 tccagcccct tgtctggagg tcgtggatta agcgcatctg gtcggctata cccgtcactt
    26161 gcaccaacgt cctatctaaa aatataagtt gggtcgacat cttaccgtct atgacgtccg
    26221 cagagtcctg agagatggaa ccaacgccct tggacgaggc cgtacgcccg tcgtcctcct
    26281 ctaccgcatt accggtattg aaatatttgt cggcccaacc aaacttacgg tcgaggtcgt
    26341 cggccagctc ctgcgccttc cgatccagat aatcctgttc ccagtcgctg atataatcgt
    26401 cggaccagaa ctcgagcagc ttctcccgga tctctttcat gggatcggaa gcggcggcct
    26461 tgatcgactc cgtgaccatg ttccttatca tcttcctcac aagatccttg gccgattgcg
    26521 ccttgtcctc cccggcggcc cacgcgtcgg cgtaagcgtt ggcgaaatcg tcgatcgccg
    26581 attttatgtc actaccgaaa atggcgtcct tgccgacctc cttgttatcc gctatggtgt
    26641 tattgatctc gtctatctgg tcccgccact ccttgatacg gtcattgtcg gttttcttct
    26701 tgtcctcctc ctccttgatc tggttttgga taagcacttt ttgctgttcc aatagcttat
    26761 tctgctggtc gataagcttg gaggcatcct tggaataggc tttctcgatg gacctgccca
    26821 gcttgtcgta cgacttgtcc aacgtgtcga tctgatcctg caaacgctgg atacgactct
    26881 cgatcttctt gtcatggatc ttggcgatag aggaggcaag ggatgtgacc accccgatag
    26941 cggcaccggc agacgcaccg atcgggccga acatcgagcc ggctttcgcc ccgtccatgg
    27001 cggagttgac cgcgtccatg gccacattca agccctcggc aataccggac ataagatcgc
    27061 tgccgaaagc gtcacctaac ttggagaacg tgtcggagag gaactgtccg gcttgcatga
    27121 tatcactcat gccggcatct atctcagcta agccttcttt tagtctcttt gtatcatccc
    27181 cagctgagaa caccttttta aggccgttcg ataccttgtt gaaagacgtg tccatctgat
    27241 cggcctcctt attgacgttg gcgatctcgt cctttatggc ctgtaacttc tccggggact
    27301 tggaaaggat atcaaattgc tccttggtca ggccgaacaa gccttttccg tcggaaccgg
    27361 tcttgaactc gccctcattg atataatcaa gcatggcctg cgcctccttg gagatagacc
    27421 gtatatcgac caccgtcctc ttgctcatgt cggagaatag cttcgtgatg atggacgttt
    27481 tcttctgggc ctcgtcatcg acggcagcca gctctttctt catctcttca ccaagggaca
    27541 gcttctcgcc ttccgtcgta gccttggcta tcttctcgtt ataaagagcc gtgatagcat
    27601 ctctcttatc aagataagaa ccgtattctt tcagatactc gttcatggca cgtttctcct
    27661 cctccagttg ttccttactc acattagagg tcgatcgctc ccgtttgacg tatgagttca
    27721 ccaaggctgt acgaatctcc acggtctgtt ccttagtcag tttgccgcct tgagcgtctt
    27781 tccactcttt ttccttggca agtatggcgg cgatctcatt gtcatagtct aggtttatct
    27841 gggcgatctt cttttccgat ccttctttca tcaagtcaat ctcagattgc tgattttgac
    27901 gacgaagagc caaaagttca tcctgtatct tttgttgaag tttcttgcgc aacttcaatg
    27961 ctttttcatc ttcacttaca actgtttttg tttctgttgt cgatactgct tcttctacat
    28021 tttcatttaa acccttaatc ctggaaataa aaggagcata ttgtttttct atcatagaaa
    28081 cagtttgctc cgtattgaaa acgctcttca cgtaatcttc cattgaagaa gcgaagtcgt
    28141 tccccaattt tactttgccg gtatatttgc gctgaatatt gaaataagcc tgctgccatg
    28201 ctttttccca agttgaaccg gctttctgga actcatcggt cgtttgcttg atttcatcca
    28261 caatagaatc taccaacccg acattcttaa ccctacttgt taaggattta cgaatctcgg
    28321 atactgccga aacctgttct ttcagaccgg aagttacaat ttcatccgtt gccgaatttt
    28381 ttattttcaa tgcgatctgt tcctttatgg aagtattgat tattgaataa gcttcgttta
    28441 tctcttccag actgctcttt tcggtcaaga gcttcggaag atattggcca tactggtcat
    28501 ttaccgcttt tatcatcttc ttccgttctt cagttccgga gtttgtacgt ttcaatgctt
    28561 caaacaaact atttaaagaa cgttcctctt tggcggcttc taccgtaaat tcgctaaacg
    28621 tcttattcag tttctcttgt tgcttctgag cgtttgtctg ataagtccat agtttataca
    28681 acgcaacgcc aagcgccgcg actgccgcag ccattaacgc ataaggattt tttagtaaag
    28741 aagccgtcaa cgcatccgtt ttccccttca atacagcaag aagagcttgc atttttgtca
    28801 taccttgcat gtgagccaaa gaggactggt aacgtagatt ctctgcaacc attgccgcaa
    28861 taacagaaac cttgtatgcc ccccacgctg cggctgaaac ttctaacaaa gatttcaatg
    28921 tcgtaagaga acgttccaaa tctccactct caaaagcctc attaaaagat ttagctatac
    28981 cagatacctc tttcaatatc atttccccca tcggacgcaa agccgcctag atattattcg
    29041 acagaagcgt catttgatta cctacttcgt ccttcatctt ctcaaacgcg gcttccgtag
    29101 cccctaaaga gctttgcaac tcttcaagat cactcgccgc cgcctttgca ttctttccag
    29161 tcaaagccag tgtagcggcc aagccttcat ccgtgccaag catttccttc atcttggaag
    29221 cggaaccacc agccttctca taaatcaatt gtaatgcctc ttggaaagta cggccttgga
    29281 atgcggcgtc tccaagttct ccagcggttc cttggatagc ggcacggatc tgtgtcatag
    29341 cctgcgccgt cggcgttcct tgcttggtca atgacgcgac agcacccaac acttggtcga
    29401 tactaatccc atacgcagcc gcaataggag caacttgggc tatagaggct cccaattcgc
    29461 caaatgtagt cttacccaac cggacggttg taaaaagctg gtccgagacc gtaccggctt
    29521 cctccgcaga catcttataa gcattcagga tcgttgtaat ggcatcggct gccgtctcgg
    29581 tttccgtaag tcctcccacg gcagctttag ccgaaacttc taggatcttc ataccatccg
    29641 ccccgtcatg tccggcggag acaatgctat ataacgcctt ggcggcctcc ggagccttga
    29701 tcggtatctc ttgggttatg gacatgacct gattcatgaa accggtcata tcatccgtta
    29761 cctgcgtgga aatggtcgct acttccagca tgtttttccg gaactccttc tcgaagtcgt
    29821 atgagctctt cgcagccttg gcgaacgccg ttgccgcact gataccgata ccaccgaata
    29881 cgtcaaaaga cgtgatctca ccggccaagg tcttgataat ccccatcgct tcacgctttc
    29941 cttcatataa gccggagtta tcgatgccgg ttaccatgta cagcgctcca tccctattcc
    30001 tgattcccat aatgcgttta tggtaaaata taggacagcc tttcatgtga gactgtcaac
    30061 cgctaaaaat tcacttataa gttatttttt cgacattttc ttttgtcttg tcgctttttc
    30121 ttcgttcttt tgtaaaaaga aaaattatcg tggaattcga gattatcaag ataaagcaac
    30181 tgtcaggcaa aaaggctcag atatattctg ttattctcgg tcaagaggat cagagcgttt
    30241 ttgaacaatt tcttcagaac aactattctg aatacccaac cgaaatagaa gatatcgtat
    30301 ctaaattgaa aattatggct acaaaaactg gggcagccga acattttttc aagctaaacg
    30361 aagggaaacc cggtgatggt gtctgcgccc tatttgatag tcctgataaa aaattaagaa
    30421 tctattgtat tcgatttgct aacgttgcta tcgttgttgg aggtggagga tacaaaccca
    30481 aaaacattag agcttatcaa gaaagttctt ccttaaaaaa agaagctgaa acagtggttc
    30541 gaatatccag aatcatatca gaagccatca aaaacaagga tatacatctc gatgataacg
    30601 gttttttctt aggtaattta aaattgaagg aggaataaat atgaacaata catctatttt
    30661 ggatacagta cttggcaata tagacacgaa aagagccaag aacatggaaa gacgtatgat
    30721 gcttgctgta aaaattgcag aaggtatcaa aaggaaaggt ctatcccaaa aggaatttgc
    30781 cgagaaaatg tgtaaacgtc cctctgagat atccaaatgg ttaagaggag accacaactt
    30841 tacaaccagc actctttttg atattgaaga tgttttgaat atccatctta tagatatcaa
    30901 cgaatattct catgcagctt gtccggcctc gatataataa aaaaatgaat ggaatacccc
    30961 ctgtgggagt aacaatgatt aatgcacacg gtatcctcct tttcgtagga gggaaggaat
    31021 attatctatc gtatgacaga tacccttggt tcagaaatgc aaaagtatcg gatgtattgg
    31081 acgtgaccat gccggacgag gattcgttgc gttgggacgc aattgatgtg gatcttgaga
    31141 ttgacagcat aatccatccg gagcgttacc caattacttt tcgctagaag acaccgctct
    31201 ggttatcgag cagacactct gaagatcttg acacatttac agagaacaaa aaccgaccag
    31261 cctcacggtt cgtcggtttt tttacaacca aaatcactat gacaaacgtt ctctacgcaa
    31321 agtaatatat atcataccgg gctcattctt cgaacccttt tcttttttcc cgtatcgaaa
    31381 tcgattacct cgacccactc gccatgatta tccccggatt catcatcgtc cacgagcagt
    31441 gatttgttcc ggtcgttcac caagtaacca tgttcccgta gcatggacat gacaagcgcc
    31501 agatcgctgt ccaatgtccg ctcatgcgta tacccgaacg cctcgttaca tagtacaagg
    31561 aacatgaagc tactttgcgt caccggctcc gacctaccca agtctcgttg ttttcttgaa
    31621 gggctattat ctcctcttcg cttaacgggc tcacagcttc caatgctatg atagtacgag
    31681 aaaaagggtt acaacccaga cgaaagagga tagcgttcaa aaggatatac aggtcttccc
    31741 atgtacaatt atccttcagt acctcccgga accaagcggg catgtcccct ttcttgttat
    31801 ggatacccaa acatacgatc tcaaagatca actcgtcata tttcgccatc aactccgaca
    31861 gtacactatc aaacgtaaca tccttatgag ccacgatagc atccttgtcc accttgtcaa
    31921 tccgcaagag taacggccgt atcctaaacc cggtccttac cgtgatcggg gtgataacga
    31981 tactatcacc aacgttctta cccgccggga tcgtctccgg cttgaactcg aaaggaatca
    32041 cgactgaccg acttgtcacc acgtcgctct caatctgtag tgctcgcttt acgctcatga
    32101 ttttcctcta aaatataaga gccccggcaa aaaccgaggc tctagacaac ctaaacaaaa
    32161 aacatcattc cgtgtcttcc gatacgacct tcaccgccct gctatacggg gacgcttgtt
    32221 tgccagccgc agataccggt gtcatgatcg tggcctttac caataagaga tcgcaattct
    32281 ccttatccgg ggcttggctg atcttcccga acacagagca cttgacaaag acatattccg
    32341 tgaacttacc ttggtacggc aggctttgta gcctgatcgt cttcaatatc gagggcgtag
    32401 acaagggagc ctcccattta tcaccggaaa cggttccccc gcaaaacatt ttcatctcgt
    32461 cgctcgtagg agaagggata gtgaactcta tactggaagg atctcctttc cgactcacca
    32521 ccgcccaagg atcctcatgt cccatggacg taaaactaag ctccttggcg tccgagaaat
    32581 tgaatgtcac cgtatccacg tcaacgcatt gggtgaactc ggtaccggcc acgccatccc
    32641 cgggttccgc aactcctaaa tacgccacat ccagcgctaa acttctttcc atatcactaa
    32701 tctaattctg ttataacctc taatctaata ttcgtacaat cgaagccatc cttggcctcg
    32761 cccataggct cagaccagac gatccgagat ttccaataca tccccaacgg cggcttgata
    32821 tcccgcaaca cgaacctcac gcctcgtacg gtctctatca tcaactgtcg atccgatacg
    32881 cctttcgagg gtctcttgac gaagatattg atatttatcg atcccttgtt gacataatct
    32941 ttcccattca aggccagaga gcggatcgtg atatgatttc ttttctcgcc atcgccggat
    33001 tgatccttat acaggataaa gcccatactc gccggctcaa ccgcattata tacgatatcc
    33061 actatatcaa actgatctgc catgttcaat atcctttctc agcgagttta tcaaataacg
    33121 ttcgactctg tttcttgatc caatcctcgg catgttccgt ggcgacagag ataacatcca
    33181 gattttcgat tgcttccaca tacttggcat aaggcatagc ggctacacca atcaataccc
    33241 agcccctttt ataaagaggg atcagctcgg aaaccaaacg tttcgcttcc ctgataccgg
    33301 tctgtttatc cgttccttcc gtggattgct catagttctc ggtcaatata tcgccatcct
    33361 taacgatcac atagccgatt gaactacgaa gattgccggt atgattctga tagttccctt
    33421 tttttcgagc gatcttcacg aactcttccc cggcacgttg caataacttg tatatccgct
    33481 cttccgcccg atccacatag taatcgaacc aacgccctac ttccctatca ctccacattg
    33541 gagtcaaacc acctttcctt gccataaact acacatagat tacagagtga gtctgaaacg
    33601 gttcccagct aatgatatcc acatcgagag cgatactgtc aatccggata tgcttcgcgt
    33661 tttccacagg acgggctttg gtcgaaaact caccatgcac gatgaactct cttccatcga
    33721 cgttccgctt caactgctgt ccactattgg acgggtagta ttgcccagtg acctctattt
    33781 ccgtcggttt accggcaacc aattcccctt tgaccaattg acaggtttga atcgtcacta
    33841 tcgcagtatg tgaatatcgc tttaccatct gtttctcgcc cttcctttgg gtacctcgat
    33901 cttattgcct atcaattccg ctttctccgg ttctcctccc tcccggtata gtcgtttcgc
    33961 cgtagcgtca taccatgcac ggggatacgt gatagagagc ttgttttccg tgaagtccgg
    34021 cagaccgcca accatggaat aaaggtcggc ggccaccagc ttttgttttt ggatatcgat
    34081 cgtcttacta tcttctgtac cttcaaaacc gcgtcccggc aaaacgacgt tatccaaaaa
    34141 atcttcacag tcagccagac cgggataagc gagtatcgta tctcgaatcg tcttagccat
    34201 gattgttatt ctccgttttc agtatcctga atcgtttgat cctccggttc gatggtttca
    34261 cccaagaatg tcgccgggat atcatccgta ccctcggtat cctcggaagc gttccaatcc
    34321 ttcccatcca ctttcatgat gaacatggca tccggatcat tcacgacagg aatagcgttc
    34381 gcttccgctt tcgtccattc cttgaacggt tccagctcag accatttggt taccaagatc
    34441 caatcctgct taaccatgag agcgattttc tgcaaggtag cggaagactc ggcggcgatc
    34501 ggcccatgct gaatgtcacc caccttcaaa tcctccaaga agcatacacg cttacgctcc
    34561 caaggattga tcgtcttacg acgatgggca cgatcctcga tacggacagc cgggttcacg
    34621 gtaatgatct tcacagggat ctcctgctcg gccagatact cgttgatgag attctttgtc
    34681 accaatatct tggaggacga attaacccat gcctttaacg tgtcgaacgt agatttctgt
    34741 ttctttagca aagagaaatc agccacatgc attacaacgt aacggatcgt caccccttcg
    34801 gcagaagcgg ccacaaccgt atcctcaata tcctgcaatc cattggccgt tgtagcgtta
    34861 ctccagtccg tagtagattt acgctggttc ttcttcggca taccgcaacc gacaaactca
    34921 gccgtaacga caccgccatt gttctttgcc gacaaatgga aacccgcacg gctcatgagc
    34981 tgcatacacc accattcgaa acgggcacga acggagttat acacgaaatc ctgatccttg
    35041 aaagccagat tcaacaatgc caactggtcc gcatcacctt gcgcgtcacg ttccaattgc
    35101 ttatactcgt tgtaatcgct ctcgttcatg ccacgcttga cggctgtctt cgggatatcg
    35161 ccggacagct tgctgatcac ctcacgggtc ttctgcggtg cggaagcgtc gaaagagatc
    35221 acgtctgcca ttaccggagc gcctttctca ccggtcagag tctcccactt caacgaggtc
    35281 tttcttttca ccccgaagaa gttcgggaag acaaccggtt tcacatgacg ggtattcaaa
    35341 cgggccgcca tgttcttttt attcacttgc ttaattaaac ttctttccat atatctgatt
    35401 ttaatggatt acacaaaacg gataaacgac attaatgcct tcaagccctt atctaccggg
    35461 aacggcatac aggattcgtt taccgtacct cttaccagta acccggactg ctggttggct
    35521 acagtcaagt cgactttatt catcgtgaca accaattcgc catcataagg caacttggcg
    35581 gctttcgctg cctgtttgtc tttagcctga accaatacct gaccttttgc ggcagcaccg
    35641 atagtcgctt ccaacgtgat cgtatcaaac tccgcattac tcttatcaat agccgtgatc
    35701 ttatcggacg cgcctgtcaa agctccacca atcgtcacga agtcacccac accaaacaga
    35761 tggttcttgg ctaccttata cgctgtcgca tcggcagcgg ccgcttctga aaccaacgct
    35821 gttttcaaca catgatacaa tcccgtttcc ggatctttca ccacgatcac gatcggagga
    35881 agctcgtcca acgacttgcc attgaacaaa gcgttccgca aatcccggcg gtcaatcgtc
    35941 ccaccgccga tcacatcctc aataatcttt tcaattccgg gaggatactg gaattctctt
    36001 tctctttttc tgtacataac gttacacttt tcttggatta ttcaataccc aggttcacca
    36061 caccgggatt attcgcactc ttgtcggcat cctgatccat cagcttcgcc caatccgcct
    36121 cggaacgctc cggaagattc acggaaccgg gagcgtaatc accacgggcc acggcatcat
    36181 cgatcgcctt ttgctggatt ccggtaaact cttcggaaag cgccttgatt tgatcctcga
    36241 tagaggtttc cgaagccaag tccacacgtc ccagccagtt atccggaaga ccagcatctt
    36301 tcaactgctt acggactgtt tctttcttag cctcgtttgc cgagttggta atggaatcgc
    36361 ccaccttctt agccatatca tcgacgctct tcctcatact ttccagataa gctttcagtt
    36421 ccgggctaag atccttcaac agctcttctt ccgttttctt gttcttatcc ggatcttcta
    36481 ccggtttacc atccttcaac ccatgcttag cttcataagc ggcgacagcg gccgtttcag
    36541 ccgtagtctt agcttcattc tccgcttctt ggattgccgg aagaatatta tccttgaaca
    36601 ggtccacgaa agcctccatc ccctcggctt tctcaatctt gaacgttttc tgaatacgtt
    36661 ccgcatactt ctccggcacg ccttttgtct tacatgccgc cttgattaaa tctaaaattg
    36721 tcataagcgt tttctgttta aaatataagg gagagaaaga aaattccggg tataaaaaaa
    36781 gcccaccgga caaccggcag gcttcatttc aattattcct ataagaatct atcttgtcaa
    36841 atcatgtgat tggatctaag ccattgtttg ccagaaggcg taaggcaata gatcaaaaat
    36901 gcggcacaag gtatgcctat cacggcgaat ccaattatag ctcccattac ttatcctcct
    36961 ttttcttatt cgttaatacc aatcctgcta ttaaggctaa aatagaagac gtaaagccta
    37021 ggccataaat cagccactta ttatcttcca tatccttgaa taaagacgct accactacac
    37081 ctgtaaagat atatttcgag acatcaatca aatagtttcc taatttctct ttccacataa
    37141 cgcaaaaata gcacaacaag atgaaaacgc aaaggtattt ctattttttc ttgtgggatt
    37201 cagaattagt gctcatcttt gtggtgtcta tcatatttaa ctaacggatg cgggtaaaat
    37261 tcgctcgcat aaacaaaacc gagcatattt tatgcccgta cattaattgt ataataatat
    37321 taggtatttg tgtacccctg tgtggaaccg taatagaacc acagcatccg ttggaatgtg
    37381 atagacagca ggaaaggcac aaataccttt ttaattatat ttattatgtc tatcaattcc
    37441 aacaaatcca atgccgccaa caatagtaac ggcaaaagga cggcccaacc ctccgaaatg
    37501 ggcaagtact ccactccaga actgcaagcc gctttcaatt ccggtcgaga gataggaaga
    37561 accgaaggaa tgctatacta catcaaacat gcttccgaaa atatgcaaaa ggaagcagag
    37621 aagctaagtg caaaattaca aatgcaaaga gcgaaagtat agaaggtgtc atcaactgcc
    37681 acaggaaaaa gtttttctga tttatatatt atctcagaaa gacgttacgt ggcagttacg
    37741 tcagtaggaa atttagaggg catcgggtgt attctgtaaa ctgccacttt actacagaat
    37801 cccctttgcc ctcgcctttt ttcggaaata tgaaaaattc atcatttaac gcaaaagaaa
    37861 ttgcaaaagt aaacaatgtg gctatcatgg caagtaatga tccaagacaa ctagttccta
    37921 tcaaacctat ttgtgatgct cttggcatag atgccaaagc tcaacgtaat agaattgatc
    37981 gtgatgaaat attaaattca accggggtca tcatgacctc ggttgcagca gacgggaaag
    38041 aacgtgagat gtattgtatt ccccttcgat atgtctttgg ttggttattt tcaatcgaca
    38101 caaaccgtgt tgatgaagaa gcaagaccct cagtcattaa gtacaaaatg cagtgctacg
    38161 atgtattata tgatcatttc tcctcttacg ccagcttcgt caaccagaaa cagaaacgac
    38221 aggctgagga ttgggcacgt attcagatct tgaagaaaga attccatgaa gccaaaaata
    38281 agctagccaa agccacaaaa caaatgaata tgaccgtgga ctactcattt gagcaatgga
    38341 aggctaacgg gaaacagctt attcttgact ttgacgatta aaattcctaa atcgttagac
    38401 aattaggaga ttatttatat ttttgcaaaa agagtagtct gatagattca gccgtggatt
    38461 gtagttccac gtgtgatggt ctatcgggct acttcttttt tataccagtc aaaaccttat
    38521 cactatccga tatactataa aggaccgctt ttcctgttat atcttctctt acaataatcc
    38581 aacttttctc acctttcaag tcaatttcaa agacatgaga atatttgatc ataggattat
    38641 ccttgtggta ttcggtatac cccttgtaat ccgaaccggc gaataccgct cctatatttt
    38701 taatcaattc gtttttctct ttcttgaact tatgaggctg attcaagaac tctttaatag
    38761 actttcctgt cattttaact tgtatcggaa aatctttatg agagaatgag ctatttaaca
    38821 aagactgttt agcccaattt tgtagttctt ttgccctatc ttttgaatat tgaattgaaa
    38881 tactatcttt ttctactttt ctatcactaa gcaaccattc cgcgaactcc tcatgatcca
    38941 tcataatcgg cgtagatatg caaatacaaa acggatgcca tcctgtaaac ttgaaatctt
    39001 tcgaatattg ccccgccttt gcatcacaca caggacacag gccatgattc gatggtgaac
    39061 gttccacctc tataccggtc acgaagtcca tattctgcca acgctcgtag tcggcagtac
    39121 gaaacgcttt atttgtttcc gtcgcagcca agcgaagagc atttttataa gacgagcgat
    39181 aaacaccctg ccccggatga taatctttca tcggctggga tgggaccaat ttgccattcg
    39241 cgtcccttac acggcggaaa cgacggttgg gttcgtttag taattgccgt atatcttggc
    39301 tgatcaacgc tgccggacga ccagaggaca aacccgaaga aagataatgt tccagattat
    39361 ccatagctcc gtccgttata tcccagacac gggaggatat ggttttacca aattcatcct
    39421 tacgtttcaa cagggtattc agcgcatctg cacttctgga aaacatctta tccttcaacg
    39481 tactggatat ggccatatcc ttgatataac ctgttaccag ttcatccgct ttcctattgc
    39541 ctaaattcca gacatcggta accgtattgg atatattgct tacgagctgc gtatgcaggt
    39601 catccaacag acgttcgatt tgcttctcta tggtagcgtt gcctatccat acacggtcac
    39661 ctccataatc cgaccattta gccagaagag gtcctatcct acggacaaac tcgtcaaacg
    39721 aatactttat gctaccttgt tgccggaaca gacattgcag gaattgtcgc tcatgaaatg
    39781 atagttcttt cattctccat atcccattgt taagccgatc atattattgc gttgcgctgc
    39841 tgtatcttcc tcttcctcca tcagcttcat ttcttcgtcc aagtcttctg ttagcggaga
    39901 atgagccgta accgtgcgct gagcgttaat cggtttgcct ccattggcaa cagagagtgt
    39961 ttgcaaggtt tcagctaaat cttccggcaa aatggaacca aattccacat cgatcaggtt
    40021 gttcaccaat tgaggacggt acttgatgtt ggtaatattg catatcccag ccaacacgac
    40081 cgacacgcaa cgctgaacca ccggaccgaa tgtttccatg ttctcactcg ccttgatagt
    40141 tgcatccatc agcatgaatt tacgagcgac accggacagg ttgccaatgc ctttcaagtt
    40201 atcaaaagaa agatccggcg tagatgtacc agcaaattgt tcgtttttcg tttcttccaa
    40261 ttctttgtcc acagatggct gggaaccggt ccacgtcaga tagtccgcat ctccatgata
    40321 ctccttgccg gacacttcat cgactgtgat tgggaagttg atatctttcc cggttgtttc
    40381 cttagagggt aaatccgaat tgccatacgt tttcaagatc ggttccgcaa agtagtcgtt
    40441 cgtatcagcc atacgggaca aacgcatttc ccgtgcatcc ataatgccgg ctacttcgtc
    40501 ccattcaggt tggaatacat cggcatacac aaccggaatc ttcccaaata gattgggaac
    40561 ctcttttatc gcccagccac ccatttcatc gatagccgta ataatcttat ccgccatcca
    40621 aatcgtgcag ctgttccgga tcataccatt agagttcact tggtaacgat ggataaaggc
    40681 atccatatca tcgttatcgt cgaaatgggg ataaaattca gagaaagtat tttcattacg
    40741 gggaacagaa agtgttttta cttttaactc cgtaatcaat ttgccgtcta atcctttgaa
    40801 agtacacgga tagaatacaa gagcagcctt actttcagaa agcaccttac gggcgaacga
    40861 cttcaagacg gattgcattc tcaatcggcg ttcccataca cgtttgaact cttggaaacc
    40921 atcgttctga tctgttcccg taatcgtcat ttgcccgcca aacaagaagg cgacagaggt
    40981 acgcaccacc tttttcggga agttggtaac gatacgtgcc acatcgacaa tcttgtcttc
    41041 caatcgtaac ggtgccccat tcttatcctt caatgtctcc gaataaaccg ccagtcgttt
    41101 cggttcacgc cagccgacag aggttttacg tcgccggcgc tcaccgtggt attctctgta
    41161 atattctctt ggttcccggt attcaatcgt atcgacacat aacgtactga ctacctgtcc
    41221 gaagtcttca ttcgcaagga tttcgcttat acttggcata attgttttat gctaaaatat
    41281 aaaagcaaat gttttttcgc tgtcaatacg gccagtctaa acaagttcac tttgaaatat
    41341 aaaaaccgag aacacatatc aaaacgcaag tatgtggcag aaaaatatcg ggattttatc
    41401 taacacgtgt cacaaatatc gaaaaaacac tttcatttta ccacttatcg tcctcttgct
    41461 acccgacgta cagagttagc cttgcacaac ccaataaact ctacattctc ggcaaggatc
    41521 gtcataccat ccggcgcatc atcatgcttg ttaccaccct ctttcttata gctggtcaaa
    41581 gctttcataa accggtcgta atccgaacct ttcttatact cgctttcttc caagaaataa
    41641 caatgcttct taatccaacc agacttcaac aagatacgtg tatccttatt ggccattgta
    41701 ggtttcgctt gaatgataca tttctcgttc tttgccttta cagccttacg gacattcagg
    41761 gcaaacagac ggccaccgtt attactctcg atgcgcatat tatcgcaacg ggtatcaagg
    41821 attagagaaa ccaatttcgg ttcagtaatc tcgacattgt cttttgtaaa cagcacatcg
    41881 gtaataaaat acttcgtacc gaatactttg gcaataggcg cacagaaatc atcgtctcct
    41941 tcgtctgcca catcggtagc accgataaca ccatccggtt gcttaccttc gatatctgcc
    42001 agcttgaagc ggttcaattc cgattttggg aacaacaacc caatagcctc gatcggttcc
    42061 tgcatatact cggcacacca gatggaatcg tccgtttcct cccgcaattc gtgataatac
    42121 tccgttgtat gcacatcctc acagaaagaa caatcgttct catccaatgc ggcgatacgg
    42181 ataatctcgt catacttccc catttcctcc atacgaccaa gaacgtccgt agccgaccag
    42241 cgggtaccga tgtcgatcga gcaacaattc ccttcgatac gggaatcatg cgttccctgc
    42301 ttccacgacc agaccttttc gttattggtg tcagatagtg catcctccaa actcttatac
    42361 aagtcgtcgg tcatagccaa catagaagca ccgaagccga tcaccgtacc gcctacacca
    42421 gccccgaagt aactcacctg ccgggcagct tccaagctcc agccatgcac gttctgttta
    42481 tcaccacgca attgtatatc tgggaagatt tccttaaacc gggaagaacg gacgatgtcg
    42541 cgcgtgtcgt aagacagctt gttatacagc gtatcggaac agcagttgcg catgaccgat
    42601 tcttccggaa aatggccgag catccacgat atgaacaaag acgagatgta agattttccc
    42661 gcacgtggag gcatagaaac agccaaccgg cgaataacac ccgacacata cgattcatat
    42721 acacgagtga aagcatcagc caccttcttc aagaacagac gcttagcgaa gagcttgggg
    42781 tcatgatata aacagtaggc ccagaaatca ttccgagcct cccgcttacg caatatggta
    42841 gctgcctttg cttgcctgat taatatgtct cttttactcc ttttcgccac ggataattgc
    42901 ttctaattct tcatccgaca tcgattccaa ttcatcaccc agcttaacaa ggttctcgac
    42961 ctctttctta tcacgccact tagccggctg ccggttcttc aaccaaaaaa tagcggctgt
    43021 cgtatccgga ggataatgct cgatatactc tactttatcc gtaatccggc cctcattggt
    43081 agcgaacttc gtagccttgg catcgtagcc aatcgcacgg ctgtaaagtc tcgaagcgac
    43141 attcgcatcc gccacagcct ttcccttttt taaggactca agaaattgag gaaacttctt
    43201 tttccagctg ttcaacgttt gttctgagac agagaagaac tcagcgatct ctttatccgt
    43261 tgcacctaac agacaaagtt ttagagcctg ttccgcatac tcttctctat attcagattt
    43321 acgcccccta cttttctttt ttacttcatt cttctctgtc ataattaacc aaaactaacg
    43381 aatcgggaca attctgccct caattcaggt aaacttccat tatcaaaata gaaagaagaa
    43441 cgcattttac cttctttctt tacaccacgc atcgacttac acaagtgttc cccttccaat
    43501 acgataccca ttgctaaagg cggatattcc gaacctaacg cttcttggag catcacgatg
    43561 atatctttcg ctaatcgctc ttgtacctgt aaccgtgccg cacaataatc aacgacacga
    43621 ccaactttcg atatgcccag tatcttacct ttgggattag gaatataagc aaaccaatac
    43681 ttcccaaaga aaggcatcat atgatgttca cacattgaat aaaatccacc tgaatccgcg
    43741 ataacactat cacaagaaag gccatccacg ccatttggga agaccgttat tttaggcact
    43801 tgtgacagat catatccacg aaagatctct ccccacattc ttatgatacg atccggcgtt
    43861 cccctcaatc cctccctgca aggatcctcg cctataaaag aaaggatcgt tcttatcgca
    43921 cattcaatat cttgtgtgtt tgtaagctta acttccattt cggatactct ttaatatagt
    43981 taataacttc cttcgtattc cggccggaac aaggctgcaa ataatatact cccgctgaat
    44041 atttatcata ttgcgacata tcctgtccgg tatagactac cttcagttca ttcgggttga
    44101 tcacgactgt tttaccgccc tcttttgggg aacacgtaat ccagtctata tttacaggtg
    44161 gaactaaagt tccatttgtc tcaatctgaa caaatcggcc agtggccttg atcttatcaa
    44221 ccaaatcata tgtaacctgc atacaaggct ctccgcctgt caatacgaca tgcaaagccg
    44281 gataacgcct tatttccgca ataatctcat catcacttaa catcttgcct tctttgtgtt
    44341 ccgtatcaca gaacgggcac ctcaagttac atccagagaa gcgaacaaaa acagctggcg
    44401 taccagtaaa gtagccttca ccttgaatgc tgtaaaaaat ctcatttatc ttcttcatac
    44461 cacgctatat tattctctga ttcctgaacc atcaccttaa aacattgagg tatctggtca
    44521 cagatccact tcgctatatt ttccgctgtc ggattaaacg ataatacctc attcaagttc
    44581 ttatgatcta gtttctcctg gatcattcgc ttgacatggg caaagtcgac aaccatacca
    44641 tctggattca actgtttaga cctgcaccaa acgattacga tccagttatg cccatgcaag
    44701 ttctcacact tactcgcata agagagactc agacgatgag acgccgatat ctctagacgc
    44761 ttccttactg tatacatacg atttttatcg ataaagagtt aatacctgtc ttatctcttc
    44821 ctcctcccgt ttccggccat actcgccaga ttcgatcaaa ggaagtattt catgttttat
    44881 ataagatata ttcctgccga ttacatccat ggaaaacgga tatccgttca acgcaaaagc
    44941 aataaattta cggaaacacg gtttacagtt ccaacattcg tgcccatcaa caggagcata
    45001 acaactgaac gatgaactaa acgcttcact aatattacct ccttgagcta tatattgctt
    45061 caacaactca gtcttggtat atgctttata gtccaagttt atcttgatcg ttcgtttttc
    45121 tgtccaatgt tgtttttggt agagatagcc gagtaagtcc tcatacaact cggcaaatac
    45181 aggcgattta tcaagaacac ggtcacccgc tgtcgctccc aaacagattt catcgccata
    45241 gttcgtcgca ataccgatca aatacatatt cctgagaggg ataatcttat cttcacgttc
    45301 ccactttgat aaatccaacc tctcaatgat ggtatcatcc ggaagacgct tcatttcctc
    45361 ttttgaataa cgggtattca tatcgacata aagccttata tccggtttcc agagtttgtc
    45421 tatcaaccaa ctatccatac ctcctgaata cagaaggact ttcttgttat aagtatcgtt
    45481 ccgcatacct ttgaaatttt atccactcat taaaattgtg tctattcgat aaatcatgat
    45541 tcttagccct catcccttgg ggaggattac gatatatcat ttgcttgcca ttgaagaaat
    45601 aaatctgccc aaatctggaa ccggacaacc aagtcgtact atcaacgcta tcaaacttca
    45661 aaaaaggaag aaatatcgta tctgtaaatc caagcccatg aatacgggta ccgacagagt
    45721 gagcttgatc gataaaccat tttaatatca tgggattacc tcttatccgc ctaccctctt
    45781 ccatcgcaga ggtcgtaccg atcgcaacat agggataatc ttcacacatc cgaataaaat
    45841 aatccttccc ccggcttgca tgccaaacag gaataggccg ccgccctgta cgatcttcca
    45901 aatatttacg gtaatactcg accttctcca gccctacaac aacatctata tccagctcaa
    45961 agaagcgttg aatgttattt ttcagaacaa agtcagcata tttcttgaca tagccatccc
    46021 aatcaaaact gttattcttt ccggaaaagg ctgaaaacgc accgctatca agaatatgtt
    46081 tctcttgaca gacataacca ccataatgtc ccgatttatg ctcccaaaaa gaacttaaga
    46141 gatagatatc tttcgtgtca aggttccatc gtttggcaca aggtttataa ccggcaagat
    46201 ataagatcat agctctattt cctttccgca atgagggcaa accatcgtct ttctcttatt
    46261 ctccacctta tctgctccct caaaaaaacg atccacatca gttggtatat catcaaatgg
    46321 aagctccaac tcccaatcac caagctcatc gatgtcgaaa tcttcaacta cggctgcaaa
    46381 atcgaacata gaagtgtccg atgtatggtt atcagccaaa gccaaaagct ttcttttttc
    46441 atcctctgta gacaaatccg ttcttctgat cgctatcaat tcatttccat cagactcaac
    46501 aattcggact ttcaacccca gttctaaagc ctgctcataa acgccattcc cggcaataat
    46561 aacatcgttc ttatccagaa gaatagaacg acccgttcca cagtcctcca ggctcttttt
    46621 aataagccgt ttattcttat ctgtgtggat gcgataattc cgggggtcat acttcaattc
    46681 tgtcataact tttattctaa aatacagggg taatcaatta acacaaatac agttgcagtt
    46741 cccggatagc ctgttccacg ctccgaacaa tcacatactt actacctgcc atttcaactt
    46801 ggcgttggta ttctttttga tcgggagatt gttttcccgt cgatgtcttg aactccaaac
    46861 aaagggaagc ataccccttt ttcggtatct gaaggatcac atctgctaca cctcgtttaa
    46921 ctccttggcg cttcatatta gccgcttcta ttttatgccg gctaccaccg ttcgggactg
    46981 caaaaagaag tcgatccggc aagttcggaa aaaacaaagg tactttattg aagaactccg
    47041 actgaatccg agcttcttcg ttgtcatgat gttgcttttg ttttgaaggg ttctttttat
    47101 cagagtagca attataacat atatgtcctt cttctgtttt gatcacagat acagtccttt
    47161 tattacagat aatacaagaa tgttccttta tgctcatttt taactaatat atataagaag
    47221 agaaagatgt tccccatttt ttgaaaaaaa caccttccgt aatttgtgtc gtaccagcca
    47281 tgcgcttgag cgatagcgaa gacctcctgt tttagtttgt ttaaatccat tgatctaatt
    47341 gtcttgtttg tttttgttta ttgttgtaaa tgggggacag ttggatcctg cccgtacgat
    47401 gtttttccct gggcccaacc aaattcaaat ttggttggat ggggtgattg ggtgttagga
    47461 aaaagaagcc ccggaatcca cttcatggga accggggctt ttggggtttg tttacgattt
    47521 ggggcagagg ggggataaaa gcctctaatc attcatgagg atattttcac atacaactct
    47581 ttaaacgaag gtgtatttgt aatagctttt acttgcatcg tcaaacggtc aggctgtgtg
    47641 ccgaaaaaga cctcattatg acctttcttg atgtatccta tttttttatc ttcaaaatag
    47701 acctctacgg ccttggggtc tttggggttg tccggctctg ttttaaaggt aaggtaatct
    47761 ccttcgtgca gggtatccag gtcgaacccg taatgtgtga ttgctgcaat atccgtgacg
    47821 aacgacaatc cattgtccgg gataaaagag gccaggaact cgaagctgtc cgtctgcatt
    47881 ttcccttgcg tcatggccaa catatatagg gtatcttcct tcaaggattg gtccacctcc
    47941 caaaactcca acagccattt agtgtcggtc cgttcaaagt tgatgatacg tttggagaac
    48001 aagtccaaca cgtttttctc gtgtaccatt tgttctaacg ccaaccccgg ataaccccta
    48061 aacccatatt gcctggccct ctccacaccc tctttcagat attggaatac cacaccggaa
    48121 tctttttctt ccagtatgcc taccatgatt cttggtgaac ctttcccgac tctccacgaa
    48181 aggtatattt tatcgaaaca tctgttcatg actatgtagt attttgctta ttcgcgaatc
    48241 aatgtattta actataaaac gttttctttc ttccggtatt ttatgacctg aaaaattttc
    48301 cggcacatcc ttgtctatgt ggaaaacaag atcttgcaac atttgtttgt tgtaaagtaa
    48361 ttttaccctt tctaaaacct gatgcactat ttcataatca tccaaagcaa tggtattgac
    48421 caactctata tgattcaagt tctcattatt ccaccgaata tcaggtttcc cctttccgat
    48481 gaaatgatcc atcttttgtt cgtcagctaa caactcgcag accttttcat cagacaattc
    48541 cctggctagg ctgctaccgc tatcatagat agtggaaaag gtggtctttt gccgggttat
    48601 gattttcttc aacgattgga ttgtcatttt gaacttgacg aaaaaccgac agaataccat
    48661 ccatttgaca atccaattgg acctctcata gtgttcgcaa aacctgtcga acacttcgaa
    48721 atactctgat ttctttacga caagtgccca attctccgaa tgtctgtccg tatttccgat
    48781 gattgcgtca aatatgatca tctcaatcac atccctcttc aaattctcca gttgtacatt
    48841 tttcaaagca cctattattc gttggtaaga atgtgccttc ttgaaatttt cactaaaatc
    48901 aggatacttt tgtacaatgt accggtatcc gtcatggtgc tcttccttat cttcttcgat
    48961 aatagattta gacaaacagc ctattttatc attaaaagaa gcgacatcat aaatcaagac
    49021 attgaaccct aatgaacgtc ccaattcgga ggctatgact tcagaccaaa actcatattt
    49081 gtaattcttg aatcctttgt ttatggatgt tttgaaatag tacttcttgt catcgtcagg
    49141 agagatagcg ataaacttat ctctggtacc tcctgtatgg acatgaacct gagttttcca
    49201 gtttgatata tcaatatatt ttgccattca tttcactttt tgcaaaagta atacttttat
    49261 aattgatagt atcctttgtc tgaatattta agggtaatgc gctcgcttcg acaaataagg
    49321 gaaaaagagt ggatattttt ttgttgtaag ctatttctca tacgatttaa attttcatta
    49381 gaatcttcat ttttctccaa ttaatattca caccttatat tttcgttcaa aatcatactt
    49441 cctaaactca tgataggctt gttctaatgt tctagaagtc ctatcgcctt ccggtatatc
    49501 ccagcttttg gaattattga tactatcatc catggccata gacccccttt ctttctcata
    49561 ccgaccaagc cattctaaga taacagctcc gtctatccga tcataaacct ttccatacaa
    49621 tccctttttc gcccgattaa aacatagctt gaaatcatca ggcttaaaga aataaaattc
    49681 ctcgataatc aaatcagccg tctgagcagc ttgagtatct ttcatcgtct ttccgacatt
    49741 gaaaaacata actaagtcaa tgattatgtt taccataaat gcccgaagtt tcatttctcc
    49801 gaaatttttg ttcattacag caatggaaca actcggagat tgaaatacat cattaaccgt
    49861 tttcgggtgt agggctttgt aatatggcat cggcaaggct cctaagatgc tcaaggcttg
    49921 ctctgttgtt ttcggcatta gttctgccgg caagactcct gttgtcgggt ctatgctggc
    49981 cggaagctgt attgcttgtt gcttgtccat tttgatattt ttctaagtca cgcttcgccc
    50041 acttgcggaa cgtgaggttc gcactaacgt attttttgag cagctctcga taattgtgca
    50101 tcgagacaag agtgtcctgg attaactgaa gcgggaaatc tcgctttatc cgttcgaatt
    50161 gttcttccgt aaacggctct ttcagtttag ccacactagg agcattcgca gcaatccatt
    50221 gcttgaactt ttcaaaattc tcattcttgg gtttctccgg ttcggggtca gggttgcgcg
    50281 tgcctacgcg cgtataaccc tcctctcctt tccaatcctc tcctttactc tcctttccag
    50341 caggaggatt ctcgattgtt cccgattgtt cgggaatatt ctcgaatgta cccggattgc
    50401 ttctattttt gcccgaaaga acgttttcta tcacttctgc cggaattttc gacttttgcg
    50461 gtttgtcgat gcgctcactg gaaaagtcca tcacgtagta gcttttgttc tcgaatgtaa
    50521 aaggtacaag gatagagttt tcaatcagct cttgcagcca tccagaaatc tgctgcttac
    50581 gaatatcttc gcgggcagga aagactttcg acttaatgat agtctcatta gctaaaatga
    50641 caccgctatc atcagcaaag tttttcatgc ctatataaag cagacaagcc ggaagagata
    50701 cgttcgaaaa cctttcatct tcccaaaatt ccggtactat agttctaatt cttggcattt
    50761 ttacgctatc attttctgac gaatcaggtt catattcttc ttcaccagtt ttactatctg
    50821 gtcgtgaaac tcacttacgc cattgcaaac ggcccgagac tggacgatat tcagcgtctt
    50881 caaattcacc tctatcgtct cgatacgttt gccaccggtg tcctttgctg acagtatcaa
    50941 acgatccggc cgattgtaat atccgagttt atacacgcag tgatgcatag ccttgccttc
    51001 ttgataaaac tgggtaatac tctccaacgg gcaaatgact atgttaccat ccgtgatttt
    51061 cattccgaaa aacttttcca tccgttcgta gaagccggct atatccttca tgagcttttc
    51121 acgcctacgg atagcttcca cacgatccct atcctgtctc aacttggctt cacgggcatc
    51181 tttctttgcc aatagcctat cgtgcgcgac cttcaagttc ttaggacata cataatgggc
    51241 attacgcaag tctttaccga aataagccaa taaagacata tagtcttccc agagggacgc
    51301 atccttgata atataatggt tacggttgca aatattgaat gatggcttat aacgaagctg
    51361 ggaaaagccg tttctataca tgtgcttcag catggatatt tgcccggtct tgaggcatag
    51421 ttccgcgtca ttacctcctt tcaaaaggtc acgtatcaac ttagacggag ttacatccgg
    51481 gaacagtcga ttcagtcccc gttttttcaa ttccggaagt aattctttcc ttggataaag
    51541 ctctccaaat atcgcatata aatcaccgta ataattatat gggttacttc catattcacc
    51601 cttgatacta agaggggaac tatacgcaaa tccgttacgt cccatattta ttggacgggc
    51661 tatgatcgta cgttttccgt cttcacgaat ccattcttga acaacttcag taaaatcata
    51721 atacaccgga gaagttcccc tacgggcgtt tttccaacat agtatatgcc ggatcacctg
    51781 aaacccgcct ctcacttgca ggatggacat atacgcctcc tcatggttct tctgctttct
    51841 gctgaccttt acatctaatt gatggtggca ataagggcat tcggtcttgt cacccaattt
    51901 actattaccc gtattaaccc atatctcgcc acattcagag caccacaact cattcttaca
    51961 tttgtaagct acatggtcga acacgtgttc cttggcccat tcctcctgcg cctttgtgat
    52021 ggcgggaagc ttttcgctca atcccgccac caacttttcc aatctcgttc tcggcttcat
    52081 atcaaaacag gctcatttgt tggacactct catcaacctt cttcttggcc ggcctctttt
    52141 taagcgatcg gtattgctct tcggtcaacc ttttgatggc cgcctgacgg gcagcgttct
    52201 tttcttcctc cgtaagttct actttatggg aagaagaaac ggagctaccg acaggaactt
    52261 ttccgacctc gatattctct tcatcataat aatgtacggc cataccaaaa acctccgtat
    52321 cactcatcac gacagaggtt ccacgcttac gggcctctcc caagatataa cgacaacact
    52381 cgtctatact ctttttagga ttggcaagtc tcggggcaaa cagaagatct tccgccgccc
    52441 tctcctgtaa atatttctgg attgtatctt tgaactcttt cataacttac gggattgtca
    52501 tgggcattaa taaataggta agttcctcgt tcccggattg gttctccgga gttatcaaga
    52561 tagcgcggct aggctcgcta aaggaaagcc tcgtacgccc gtcatcgata catgaaagta
    52621 tctcaagaag caacgatccc ttaatcccga tcgagaactc attcccgtta aaatcgacct
    52681 ccaacgtttc ctccgcggaa gtcgagaaat ctatgtcttg ggcgaatacg gtcaacttat
    52741 cacgaatgat cctcaagacg ataaggcatg aggccttatt ggagaacacc gatgtccttt
    52801 taatagcccc gatcagttgt ccggtgtcaa caagcagttc cagcttattc gccttgggta
    52861 ccacagcttt ccaattagga tatctcccct ccacattccg gaacgatatc tcatagtcat
    52921 tgagtatgac atcggaccaa tccgcaccga ccctcatttc catgttatcg gaggaagccg
    52981 gaagtatcgc cttcaatacc gaggctatag gacggctgat tataactgag atcttgccaa
    53041 cctgtctatc attgcccttt ctcaagaatc ccatgccatg cccgtccgca ccgacaaagc
    53101 atacggtctc cggttccgtc tcaataaaga cagagcttag gaccggacgg atatcatcat
    53161 tcccggccaa atttatgacc ttggatatcc cattgaataa atcctccgcg ctcaatgaca
    53221 cagagtccaa gacctcgatc gatctttttc ccggataggt agatgggtca taacccacca
    53281 cctcgaactt tccaccatgg tacttgatcc ttatctcacg ggtatccttg ttgatgatta
    53341 tatcaattgg ttgctcgggc aggttcctca gtccttctaa taaggaagtc gggacacaaa
    53401 tagatatctc ctcgtcgaag atgcactcaa ggctggtggt tatccggccc tcgctattcg
    53461 atccggtgat gaataaccgg ccttccctcg tcttaaacaa gaaatgacaa aggatcggcg
    53521 tggatgattt ggcgggtatg atcttcgcca aaagctgcaa tcttgatagc agcgctgttt
    53581 tagaaataga aatcgtcata gtgcctgttt tttttgaagg cacccggtaa gtctttgttt
    53641 tatggaagtt tacagaaata agagaccaaa cacatataaa cacaaaaagt tggatctcaa
    53701 actttcgtct aaaatccaac tcgctatttc aacgacaaag atagagtcat ttttttaatc
    53761 cgcaaattat ttccatcttt ttttcgtttt tttcttcaaa tacataatca agaatcttgg
    53821 cattcaagcg gtcgataacg ctaaaatcgg tcttaacata cccagatgtc accctatggg
    53881 aagaagcatg gttaaggcaa aagcctacta aatccaaact tgcatcgaaa tcgttttgag
    53941 cgaatgtagc ccaactatgc cgaaacgaat agacagaaat atgaggaagg tcgttttttc
    54001 ttgttatatc acttattccc tcatttatac atttattgaa attcttactt gatccataag
    54061 tctcacagaa gttaaacagc cttttttctc cagcatattt ctcaagcaaa tgagatagcc
    54121 tatctggtac ggctatctct atatacgcct tgtcatccct cctattagta gtcttacgtc
    54181 tgcagtaaca catctttccg tctctaaggt tctctttttc catataatac aggtcagcgg
    54241 tgttaattcc ggcaagacaa aaaacgatct cgcacacatc cctagcacga tcagctcttg
    54301 atccatactc cgcggatacc gcaaaaaaat ctcgaacggt tctaatgtcc aatgcccttt
    54361 tctctggaac tgtaggtcta ggtaccctca ctcccctaaa cgggttattc cgtataagca
    54421 tctcgccggt atcataatta ttataccgct cgcatccagc cataaacatt gtcttgatcc
    54481 gcttcggata gccatgtttc ttgtacaagc tatctttcat cgaatctatc cactccttga
    54541 atatagacga tgtaagatca gagaagagaa tgtcgtcttt ccccatatat tcctccaagc
    54601 gccttaacgc aagcttataa tttatcgacg tggattctct tccctcgtta tccatcttag
    54661 aggtaaaccc ctcacaaaat tcagaaaaag aaggtgcgct agaatccctc ctcaagaagt
    54721 ccagtatctt tctgatatcc caacattgta tatcttcacg attaagccgg gacatatacc
    54781 cgtcaataag aatagaaata tccttgatga tgtaattatc tattacctca cccttccgaa
    54841 cagacttagc cttgcagact ttatctgttt ttatatatcc tacctgtccg tgatgggtta
    54901 cacgaatata aacaggatac gtattgtctt ttctcttagc tcgtacgcaa attttgaaat
    54961 atgccataat ttttactgta aactatttgt aaatcattta tgctattcat gcaaaaaaag
    55021 cttgtatgaa taggtatgta aggaggctaa aatgaacaaa tctcctacag tatcattaca
    55081 acaaagagct aataatcaag cggaaagact gggattcgaa cccagggagc ggttacccgc
    55141 tcaccgcatt tcgagtgcgg cccgttcgac cactccggca tctttccttg tggtt
//
LOCUS       DBMDTB010000012        54100 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_251_length_54100_cov_10.549418, whole genome shotgun sequence.
ACCESSION   DBMDTB010000012 DBMDTB010000000
VERSION     DBMDTB010000012.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 54100)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 54100)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54100
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_251_length_54100_cov_10.549418"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..968)
                     /gene="serB"
                     /locus_tag="ACZPB4_03595"
     CDS             complement(<1..968)
                     /gene="serB"
                     /locus_tag="ACZPB4_03595"
                     /EC_number="3.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036424 - L-phosphoserine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006564 - L-serine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoserine phosphatase SerB"
                     /protein_id="HIR1097338.1"
                     /translation="MAQNDEIILININGADRPGVTAALTEILAKNNAVILDIGQADIH
                     NHLSLGILFQSTEGNSGDILKELLFKSYELDVNIRFNPITEQEYSKWVGMQGKNRYII
                     TILSRKLTAKQIAGVSRIVAEQDMNIDDIKRLTGRIPLDENARTPKASVEFSVRGTPK
                     NKECMKAEFMKLSTELEMDISFQEDSMYRRMRRLICFDMDSTLIETEVIDELAIRAGV
                     GDQVKAITEAAMRGEIDFCESFRQRCALLKGLDVSVMQEIAENLPITEGVDRLMRILK
                     KVGFKIAILSGGFTYFGNFLKQKYNIDYVYANELEIENGKLTGNHVG"
     gene            1070..1663
                     /locus_tag="ACZPB4_03600"
     CDS             1070..1663
                     /locus_tag="ACZPB4_03600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010182996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097339.1"
                     /translation="MFNENLATLKSPDRQAKCMRIQFEIKEKLPDIISEILHSDKWLT
                     LVRDENHGLRRVTIKDPYFDSEACVDIWEHEIHVTTAWSNYTYRIYQKGNSVWCEYIG
                     AYRGLLEQNLLPTMTPKENILDSEVLNSSLFGDRKETLRNYSAENLKLKNFRRDNFAA
                     EYQLASPQDHPKIVYDEFIKEGVPIPPPEDRKEKSGN"
     gene            complement(1688..4000)
                     /locus_tag="ACZPB4_03605"
     CDS             complement(1688..4000)
                     /locus_tag="ACZPB4_03605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane beta-barrel protein"
                     /protein_id="HIR1097340.1"
                     /translation="MKQIIMAALLISFSWGIRAQQLQIRGKVIDLSDKSPLEFANITL
                     QTADSAFITGTTTDSKGLFRIEKVKAGDYQVSVSSIGYKTSVVSVLGLSQPIDLGTIS
                     LASSSISLDEVTVNASAIRNTADRKITFPTSEQKAASSNGINLLNALMRPRLEVDPIR
                     NSVSLSNEGTIQFCINGIKVELSDIRGLSPQEVIRVEYHDNPGLRYGNASVVLDYIVR
                     RETSGGSVNLDLSNSPTTSFGDDQVSAKFNHKKSEFGLQYAVRYRNPYHIWTEGTETF
                     RFENGETLERTSEGLPGRMSETSHNLSLNYNLVDNDHYYFNATLRYFLSDEDKGSNGK
                     NLYANNHPEDKTYAWNPNSNSTKRPSLDLYYQRSLPHKQTLILNMVGTYIHTNANQMY
                     QEWKNDILLSDILSNVDGDKYSIIGEGIYERQFEAGRLGGGLKHTQSWTDNTYSGTVG
                     GRTKMKQSETYLYTEFSGRVKKLNYTAGIGVSRSWFKQEGEEDYQYYTFRPKVSLQYN
                     FTDNMYFRVNGSVNNVSPSLSELSAIEQYIDTLQIRRGNPYLKPYKSYDMQANYLYKK
                     GIFTGDLNFYYSNSPDQIMEEVIRENNKFIRITDNQKGWQKLSGDLTLRVGPIIKRII
                     SLSVTGGVNRYISEGNSYSHTYNNWYYRASVMAMYKKFMAMFQIQSSYNTFVGELLHG
                     GENIHMFMFRYNQGKFAVGAGLMMPFSSQYKRVEENRNAYAPSRTNMYANDFSRMLML
                     TFSWNFDFGRKFKEANKKLWNSDEDSGIMR"
     gene            complement(4046..4453)
                     /locus_tag="ACZPB4_03610"
     CDS             complement(4046..4453)
                     /locus_tag="ACZPB4_03610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097341.1"
                     /translation="MKKSNCVFIALIGTLYIVPALTFGVAQFTSEKCLTGFTQKFQII
                     QIDNPELKAENIKVDTRTASEFPRGQILEAKDRSLLYYEGMKRYLPEVSRHDSLLLVS
                     GARGAGQDKNLTLHIRINNIQKIRLNGEEIWTR"
     gene            complement(4462..4830)
                     /locus_tag="ACZPB4_03615"
     CDS             complement(4462..4830)
                     /locus_tag="ACZPB4_03615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HIR1097342.1"
                     /translation="MNYNTNQSIFIQIAERICDRVLSGNYKADSRIPSVRELAVEMEV
                     NPNTVMRSFERLQANDIIYNKRGIGYFVASDAEQKIREMRHNQFVEEVLPAVFKEMHL
                     LDVGIDELTKAYTLYISTIK"
     gene            complement(4827..5543)
                     /locus_tag="ACZPB4_03620"
     CDS             complement(4827..5543)
                     /locus_tag="ACZPB4_03620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097343.1"
                     /translation="MKTDFSIQRINLLLRKDWIENKKKLAYGVLVILGVLFFFLLSSI
                     LWDTRFRTFTLYVLGSLGTFIAFCSYVNLMIHRPRGLFLTLPASNQEKFAAILIEGIV
                     VFLTYQVTFWTGTGIASMLIHIQPVAFKDIIMTLQDFTMLAFVGSLMFLSYVTFKKYA
                     LGIACGGYILIIASIIGIVYLCINILNIQPGMNSFCYESSPFYTAVYWLSFAFTPAFL
                     IATLVVLYVAYLKLKEKELR"
     gene            complement(5557..6384)
                     /locus_tag="ACZPB4_03625"
     CDS             complement(5557..6384)
                     /locus_tag="ACZPB4_03625"
                     /EC_number="7.5.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1097344.1"
                     /translation="MITLKELSFSYSRKKEVLDRINLEVGSGHICGLLGKNGEGKTTL
                     LNLLSGQIFPDQGSCLALEEIPSERNARFLQQIFLLPEEISMPEVTAIEYIKMYAAFY
                     PTFRDDICKACVESFEINLSDRLSKMSQGQRKKVAITLALAAHTPLLLMDEPTNGLDI
                     PSKATFRRLVASLIDDNQTVIISTHQVRDLESLIDTVLILDQRQILLNKTLNEIGEKL
                     YFGPLLPEEKALYSEPTPQGTIGVTARDGKEETAVSLELLFNAAITYPKEIQRIMNS"
     gene            7042..7542
                     /locus_tag="ACZPB4_03630"
     CDS             7042..7542
                     /locus_tag="ACZPB4_03630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HIR1097345.1"
                     /translation="MKVRAYVLIASVALLGMSAGSKKAKLTEGVNPGDLAPRIEFLGN
                     DAKASFHNQLGRYTLLNFWAAYDAESRARNVQLANEVNKFGPDKIAMCSISMDEKESI
                     FTETVKIDKLDLSTQFHEGLGKESELYKKYDLRKGFKNFLINDEGVIIAANVTPEKLT
                     EILKAI"
     gene            7784..8464
                     /locus_tag="ACZPB4_03635"
     CDS             7784..8464
                     /locus_tag="ACZPB4_03635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097346.1"
                     /translation="MRSILFFICLIFTFEGQAQEVEKSHMWKVELSGALNNNSAWEVE
                     PSVTYLPIPYVGITMGLLFCNTIEKDSYTGFSRDNQWFWDSDESNPGCHFFALRPAIQ
                     LVTPTFKFGKDKDTGLSLVVSPGLTIPLPVNQEFNISYVPNTPGVWIPQKFDHIKNKG
                     GKSLFYHIKSMLSLDIDQRYIFSLGYIFSNFDLYSGGRNFVVEGKRLSMPRIRFMHSF
                     FLSIGYRF"
     gene            complement(8564..9937)
                     /locus_tag="ACZPB4_03640"
     CDS             complement(8564..9937)
                     /locus_tag="ACZPB4_03640"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HIR1097347.1"
                     /translation="MFSKETYMARRAKLKQTIGSGLLLFLGNDESGMNYADNTYHFRQ
                     DSTFLYFFGLPYAGLSAIIDIDNDKEIIFGDELTIDAIVWMGTQPTLKEKSEAAGIKE
                     VRPFKEIETYLKNAQQKGQPIHYLPTYRAEHQIKLFQWLGIVPGAEKPSVPFIMGVVN
                     QRNYKSEEEIAEIEKACIVTADMHLTAMRTVRPGIRESDVAAAVAEVAFANNYQLSFP
                     IIATINGQTLHNHDHSHMIKSGDMLLLDAGAETEMGYAGDMSSTIPADSKFTTRQKDI
                     YDIQVAAHEAAVAALRPGIPFVDVYELSCKVIMEGLKDLGFVKGDPMEAVKAGAHAMF
                     MPCGLGHMMGLDVHDMENLGEVYVGYDGQPKSTEFGRKSLRLGRKLEPGFVLTIEPGV
                     YFIPELMDLWRGQNKFTEFINYEKLFTYKDFSGIRNEEDYLITENGARLLGKKIPLRT
                     EEVEAIR"
     gene            10050..10394
                     /locus_tag="ACZPB4_03645"
     CDS             10050..10394
                     /locus_tag="ACZPB4_03645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097348.1"
                     /translation="MKIQRIQELTDASIVCGSEKRENDVQCAFASDLMSDVLTLDCGD
                     VLLVTGLCNLQTIRTAEMAEVSYILFVRGKKVTPDMLELARENNMVLLETDHSMYHTV
                     GELYSAGLLPIY"
     gene            10413..10838
                     /locus_tag="ACZPB4_03650"
     CDS             10413..10838
                     /locus_tag="ACZPB4_03650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HIR1097349.1"
                     /translation="MLFKFELEGGNFSKAGYASSQIKKVLKQLAIDPRIIKRVVVALY
                     EAEVNIVAHAWRGTVVAELDADKISLELKDEGPGIPDISLAMREGYSTASEAVREMGF
                     GAGMGLPNMKKNVDELTIESQVDVGTTVRMVTWFNKEGA"
     gene            10842..12221
                     /locus_tag="ACZPB4_03655"
     CDS             10842..12221
                     /locus_tag="ACZPB4_03655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[Fe-Fe] hydrogenase large subunit C-terminal
                     domain-containing protein"
                     /protein_id="HIR1097350.1"
                     /translation="MEEANFYHALKIDNDRCIGCTHCMKECPTGAIRIRDGKALIHKD
                     WCVDCGECLKSCPTEAIYVEQDDFQRIFDYRCRVALMPTVFIGQFSKYTTEKEIISAV
                     MELGFTHVFQVEFTADMIHKEMVRQMENAEEKPVISSFCPAIVRLIQVRFPALVDNIL
                     LVKAPVNASATYYHKILEGQGVPSEEIGIFYVTPCAAKIAALKGAEGYSSTIKGVINM
                     DTLYNKVYHILKNRPRGYEPECELPPPLTKKEMRWSQTGGEAKHFSGRCLAIDEIHNV
                     IDFLERMETTSEVRNVDFLELRACDRSCAGGVLAVANRFLTAERIMKRSMNRDKVPMI
                     YAADNFEALSYLRQHITIRPVQPNPKRLYDGTIDEMLKKMEQVRKLMCYLPGIDCGAC
                     GSPNCQSLAEDIVRHEAQFSDCVFMQRNMEKHGKLDQEHAFRIVEKTWGKDRLNKDCY
                     KKGAKYEGL"
     gene            12208..12552
                     /locus_tag="ACZPB4_03660"
     CDS             12208..12552
                     /locus_tag="ACZPB4_03660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DRTGG domain-containing protein"
                     /protein_id="HIR1097351.1"
                     /translation="MKVCDLVKMLNLTVFCGEEGLDTEITGGYTSDLLSDVMGHIEEG
                     MLWITMQTHQNILAVATLKDASAVLIVNGTSPDDETLQKGREEAVPLLGTTRSAFEAS
                     GMIYRLLQNENG"
     gene            12549..13295
                     /locus_tag="ACZPB4_03665"
     CDS             12549..13295
                     /locus_tag="ACZPB4_03665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HIR1097352.1"
                     /translation="MKQYLADLHIHTCLSPCGSLEMSPSEIVRRSLAKGLDAIAITDH
                     NTTLQCPEIQSLGERFGLRVFAGVEVTTREEAHCLVYFPTDESRKRFQRYLEEHLPPI
                     PNDPERFGDQVWVNAENEILGEVPYLLLSALDQSVNQIAAQARKVDALFVAAHVERPS
                     FSLISQLGFIDPCLSLDAIEYNNQQRYSKLLSIHGYLKEQTQYSASDAHYPEQIGTQP
                     SIWQTEELTFDGLRKAFDQKDNHLIFASHG"
     gene            13288..13821
                     /locus_tag="ACZPB4_03670"
     CDS             13288..13821
                     /locus_tag="ACZPB4_03670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HIR1097353.1"
                     /translation="MDNLSFHITDITANSIRAKASDIEIDIQIKDTSICIRIADNGCG
                     MDPETVSLIRNPFYTTRTTRKVGLGLPFLIQNAEQTGGNVEISSIQGKGTVVVACFVS
                     SHIDCPPWGDLAGTMAMLIGSNPDINIHFSYHSDLVSFDISTLELKEILEDMPLSHPK
                     VMLYLKELIANQIVASS"
     gene            complement(14121..15338)
                     /locus_tag="ACZPB4_03675"
     CDS             complement(14121..15338)
                     /locus_tag="ACZPB4_03675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HIR1097354.1"
                     /translation="MKRVLLTVALCVAASVSFAQKKAVNEAQSIAKGTTPDFSEARTL
                     IKGALENPETKDDAKTWYVAGFIEDQQFSNERTKQVLGQQPDEPVMYEALGSILPYFE
                     KAYELDQLPNEKGKIKPKFTKDIKGILGANHVYYINGGAYYFDQKDYNKAYDFFEQYL
                     KISDMPMFKGEAVAERDSNFMTVQFYAAVAATQLGDSQKAIAALERAKNTDYRASEVY
                     QYLCYEYEQAKDTVNLEKTLEEGLNKFPEEQYFLMSLINNYIYSNRNEKAIEYLNTAI
                     AKDSNNPQLYDVMGRVYETGLKDYAKAEEYFKKALAINPDYIESLSNLGRVYYNQGVN
                     KQGEANMINDAKQYQEELGKAKEFFKQALPYFEKAHQMKPEEREYMTALRGIYYNLNM
                     GDKFDAIEAEMNK"
     gene            complement(15381..17993)
                     /gene="gyrA"
                     /locus_tag="ACZPB4_03680"
     CDS             complement(15381..17993)
                     /gene="gyrA"
                     /locus_tag="ACZPB4_03680"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008148025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HIR1097355.1"
                     /translation="MVDQDRIIKINIEEEMKSAYIDYSMSVIVSRALPDVRDGFKPVH
                     RRILFGMNELGNTSDKPYKKSARIVGEVLGKYHPHGDSSVYFAMVRMAQTWSMRYPLV
                     DGQGNFGSVDGDSPAAMRYTEARLSKLAEEMLRDIDKDTVDFQLNFDDTLKEPTVLPT
                     RVPNLLVNGGSGIAVGMATNMPTHNLSEVLDGCIAYIDAKGDIEVEGLMQYIKAPDFP
                     TGATIYGYAGVKDAFETGRGRIILRGKAEIEVENNHEKIIITEIPYLVNKAELIKYIA
                     DLVNEKRIDGISNVNDESDRSGMRIVVDVKRDANSSVVLNKLYKLTALQSSFSVNNIA
                     LVNGRPRLLNLKDLIKAFVEHRHEVVIRRTKYELRKAEERAHILEGLIIASDNIDEVI
                     AIIKSSKSPQEAIERLIERFSLSELQARAIVEMRLRQLTGLEQDKLRAEYEEIEKLIA
                     YLNEILENEDLCMKVIKDELLEIKDKFGDERKTDIVYASEELNPEDFYADDEMIITVS
                     HMGYIKRTPLSEFRAQGRGGVGAKGSETRDEDFVEYIYPASMHATLLFFTAKGKCYWL
                     KVFEIPEGAKNAKGRAIQNLLNIEPDDKVQAFIRVKKLTTDTEFINSHYLLFCTKKGV
                     IKKTLLEAYSRPRQNGVNAITLREDDGLIQVCMTNGNNEVIIANRNGRAIRFHESAVR
                     VMGRTASGVKGMTLDEDNTDEVVGMICIKDKEKETVLVVSEQGYGKRSSIEDYRITNR
                     GGKGVKTINITEKTGKLVAIKNVTDENDLMIINKSGIAIRMKVADLNVIGRATQGVRL
                     INLEKRNDEIASVCKVLSESEEEIAEQKAEQEARQENEGRELSENQASLGTDVDLPES
                     EEDNEQNDNEEITE"
     gene            18198..20756
                     /locus_tag="ACZPB4_03685"
     CDS             18198..20756
                     /locus_tag="ACZPB4_03685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HIR1097356.1"
                     /translation="MKNYSKRLIDVIEYSREEAARLQNSYIGPEHLMLGIIREGEGEA
                     MRVLRELHTDPMDIKRKIEQEIKNTFDSEDSVQHEIAISKTTERVLRMSMLESRLFKE
                     DETDTEHLLLAILKEEFNVAAKVLNDAGITYRSAYNILVSGTGLNNMEEFDEISDGYT
                     DDDEDDEDEGFSSRREASRPSSGTGAGAAQPKSPNDTPVLDNFGTDMTRAAAENRLDP
                     IVGREKEIERLAQILSRRKKNNPVLIGEPGVGKSAIVEGLALRIIQRKVSRVLFDKRV
                     ISLDMASIVAGTKYRGQFEERIKAILNELSKNPNIILFIDEIHTIVGAGSASGSMDAA
                     NMLKPALARGEIQCIGATTLDEYRKNIEKDGALERRFQKVIVDPTTAEETLQILRNIK
                     PRYEEHHNVIYTEDALQACVKLTERYISDRNFPDKAIDALDEAGSRVHISNIIVPKSI
                     EELEAKIEDTKNEKLAAVKSQNFELAASFRDKERQYLLQLEAAKAKWEQELQEHRETV
                     DEEKVAEVVAMMSGVPVQRIAKAENVKLLEMADVLKSKVVGQDDAVQKIVKAIQRNRV
                     GLKDPNKPIGTFMFLGPTGVGKTHLAKKLAEYLFDSADSLVRIDMSEYLEKFAVSRLI
                     GAPPGYVGYEEGGQLTEKVRRKPYSVVLLDEIEKAHPDVFNLLLQVLDEGRLTDSLGR
                     RIDFKNTILIMTSNIGTRQLKDFGRGVGFNTQMAGEPDKDFSRSVIQKALNKAFAPEF
                     LNRVDDIIMFDQLDKAAIHKIIDIELQGLYQRVSNLGYELSITDEAKDFIATKGYDIQ
                     FGARPLKRAIQKYLEDEMAEMIIRASVGEGDTIIVDFDKEEQKITTSIKKKDAE"
     gene            complement(20896..20979)
                     /locus_tag="ACZPB4_03690"
     tRNA            complement(20896..20979)
                     /locus_tag="ACZPB4_03690"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20943..20945),aa:Leu,seq:gag)
     gene            complement(20993..21076)
                     /locus_tag="ACZPB4_03695"
     tRNA            complement(20993..21076)
                     /locus_tag="ACZPB4_03695"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21040..21042),aa:Leu,seq:cag)
     gene            complement(21093..21165)
                     /locus_tag="ACZPB4_03700"
     tRNA            complement(21093..21165)
                     /locus_tag="ACZPB4_03700"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21130..21132),aa:Gly,seq:gcc)
     gene            complement(21248..22072)
                     /locus_tag="ACZPB4_03705"
     CDS             complement(21248..22072)
                     /locus_tag="ACZPB4_03705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine nucleoside phosphorylase I, inosine and
                     guanosine-specific"
                     /protein_id="HIR1097357.1"
                     /translation="MEMIKTEQYREAAAYLASRIEGNPETAIILGSGLGSFADQIIDP
                     IVIPYVEIPHFMKSTATGHKGNFICGKLGDKQVLAMQGRFHYYEGYTMQQVTFPVRVM
                     KLLGIKNLLVSNAAGGINNTFKVGDLMIIRDHINMMPNPLIGPNNEDFGTRFPDMTRA
                     YDREFIRYVEEIAASRSIPLKKGVYVGLTGPSFETPSEYAFYGKVGGDAIGMSTVPEV
                     IVARHAGLRVFGMSVITNEGYHFADDFVNDGADVIVAANKAASVMTQLFRELVKKI"
     gene            complement(22084..23340)
                     /locus_tag="ACZPB4_03710"
     CDS             complement(22084..23340)
                     /locus_tag="ACZPB4_03710"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019239 - deaminase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HIR1097358.1"
                     /translation="MSILIKNVLFNDKTIDIYIEGKEIKQIGAGLSFPADKILDGSRK
                     AVIPGFVNAHTHAAMTLFRGFGDDMPLMPWLEQKIWPNEAKMTREDVYWGAKLACLEM
                     IKSGTTTFFDMYQRPRVTADVTEEMGLRGIIAGVCFDGFDKEEAEKCKRHNERLIQDV
                     DNYSKRVRFSIGPHAIYTVSGELLKWAHQFAMEHQIPIHLHLAETEGEVKDSLDRFGL
                     TPVRYLYELGVLSPRLIIAHGIYIDDDELRMLADHEVKVVHNPASNMKLASGMHFKFK
                     EMRQLGITVGLGTDGCSSSNNLDMIEAMKLASLLGKAWRKDPEALTANEMLQAATAEG
                     AVMFGLKAGQIKEGYLADLCLIDLNTPAFTPNFNFVSNLVYAANGSCVDTVICDGKIL
                     MENKKVPGEDEIMEKAAEIAYNLMKR"
     gene            complement(23352..24707)
                     /locus_tag="ACZPB4_03715"
     CDS             complement(23352..24707)
                     /locus_tag="ACZPB4_03715"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HIR1097359.1"
                     /translation="MSVKSYIESNKDRFLEELFSLIRIPSISAKHENKPDMLTCAQRW
                     TEVLLSSGADKAEVMPTKGNPVVYAEKMVSPNAPTVLVYAHYDVMPAEPLELWKSEPF
                     EPVIRDGRIWARGADDDKGQGMIQVKGFETAIKEGLLQCNVKFIFEGEEEIGSPSLED
                     FCREHKELLKADVILVSDTSMVSAETPSLTTGLRGLAYWEIEVTGPNRDLHSGHFGGA
                     VANPINVLCKLMADITDVDGRITIPGFYDDVEDVSSAEREMIAQIPFDEEKYKKAIGV
                     DSLFGEKGYSTLERNSCRPSFDICGIWGGYTGEGSKTVLPSKAYAKVSTRLVPHQDHA
                     KISQMFEEYITRVTPPYVKVKVTPSHGGQGYVCPIDLPAYQAAEKAVGIAFGKKPLAV
                     RRGGSIPIISTFEQVLGIKTVLMGFGLEQNAIHSPNESQELDIFFKGIESVAEFYRLY
                     K"
     gene            complement(24850..25995)
                     /locus_tag="ACZPB4_03720"
     CDS             complement(24850..25995)
                     /locus_tag="ACZPB4_03720"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016413 - O-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HIR1097360.1"
                     /translation="MNNATTQSHIVWLDVIRTVAMLMVIGVHCIDPFYISPTLGSLPE
                     YKHWAAVYGSLLRPSVPLFVMMTGLLLLPIREQSLGVFYKKRIYRVLFPFLIWSVLYN
                     IFPWVTGLLGLPKEIIGEFFCYVQGNESQSLSDALKDIAMIPFNFSFKENHMWYIYLL
                     IGLYLYMPFFSAWIEKADRSKERVYLGIWFVSLFLPYMSAYISKYLYGEATWNQFGMF
                     YYFAGFNGYLLLGHYLKQGNNWNIWKTFAICAAMFVVGYAITYSGFSSAAANPKATEL
                     DMELFFTFCSPNVVLMTAAVFILLQKVRIHNTLIAKKLSKISKYGFGIYIVHYFVVGP
                     IFILIGKFDLPIPLQVPIMALLIFIISWAFTWFMYRILGERAKWIMG"
     gene            26092..26823
                     /locus_tag="ACZPB4_03725"
     CDS             26092..26823
                     /locus_tag="ACZPB4_03725"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0070401 - NADP+ binding [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HIR1097361.1"
                     /translation="MVKRIIIIGATSGIGYEVAKIYWKRGYQLGLAGRRVDRLEEFRK
                     QDPEHIRIKQLDVTAEDAADRLDELIRDLGGMDIFLLSSGIGNQNKYLDTSIEQATIQ
                     TNVTGFTRMVLAAYRYFSSQGGGHISVISSIAGTKGLGVAPSYSATKRYQNIYIDALA
                     QLSRMEKQPITFTDIRPGFVRTDLLKDGRNYPMLMSPQYAALRIANAIDRKKRRAIID
                     WRYAILVFFWRLIPEWLWEWLPIRN"
     gene            complement(26858..27190)
                     /locus_tag="ACZPB4_03730"
     CDS             complement(26858..27190)
                     /locus_tag="ACZPB4_03730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HIR1097362.1"
                     /translation="MKQLIACCGLDCESCDARIATVKNDDELREKTAQKWSAMNNAPE
                     ITAATINCMGCRADGVKFAYCSDYCEIRKCVSGKGFNTCGDCDELDSCQIVGAVLQHA
                     PGARENLM"
     gene            27305..28963
                     /locus_tag="ACZPB4_03735"
     CDS             27305..28963
                     /locus_tag="ACZPB4_03735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HIR1097363.1"
                     /translation="MGLFIKKPLADLMTEANDSGSKSLKRILGPWSLIALGVGVIIGA
                     GLFSITGAVAAGYTGPAITLSFAIAALGCCFAGLCYAEFASMIPVAGSAYTYSYATMG
                     ELVAWIIGWDLVLEYCVAATTVSISWSRYLVVFLEGFGVHLPQALTACPWDGGIVNIP
                     AFVIVVLMSILLIRGTEGSSIFNGIIVFLKVSVVLVFVVLGWKYIRMENYTPYIPTNT
                     GTLGEFGFSGILRGAAIVFFAFLGFDAVSTAAQETKNPKRDMPIGILMSLVVCTILYM
                     LFAHVMTGVVHYSAFAGQNGIAPVAIAIDHMGQMDASGVIRPDYPWMNRAIVIAILLG
                     YCSVIMVTLLGQSRVFLSMSRDGLLPPLFSHIHEKFRTPARSNFLFMLLVGTLAAFVP
                     ASVAGEMCSIGTLFAFTLVCAGVLIVRKTMPDAPRSFKTPLVPFVPIAGIITCLVMML
                     FLPADTWIRLVLWMLIGLDIYVCYGIKHSKLEHMQKHRSGQTTLDMIGITLSVLCVIT
                     GLWHQQTVGWGESKVLLIISFVFAFTHLAFYLYRLGKQFTSLTR"
     gene            complement(29111..29491)
                     /locus_tag="ACZPB4_03740"
     CDS             complement(29111..29491)
                     /locus_tag="ACZPB4_03740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HIR1097364.1"
                     /translation="MKESVRILRFAIVGSSNALITALVIWILMDILDCNYLWSNMAGY
                     VAALVNNFFWSKYWVFSSGKGNFWKEIPLFLIAFGCAYATQFIFLLLMVEVIDLNEYL
                     GQFLGLFVYGAVNFMMNKRLTFKS"
     gene            29593..29868
                     /locus_tag="ACZPB4_03745"
     CDS             29593..29868
                     /locus_tag="ACZPB4_03745"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007832603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004497 - monooxygenase activity [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative quinol monooxygenase"
                     /protein_id="HIR1097365.1"
                     /translation="MIRLNVFIQVSEENRPAALETAKELVEKSLKDNGCIAYDIFESA
                     TRSDVLMICETWKDAESLSGHEKAEHFVTLVPKLQGLGAMKLEKFTF"
     gene            complement(29981..31324)
                     /locus_tag="ACZPB4_03750"
     CDS             complement(29981..31324)
                     /locus_tag="ACZPB4_03750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005790680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate/2-methylcitrate synthase"
                     /protein_id="HIR1097366.1"
                     /translation="MKKEYLIYKLSEAAREACKIDNELFPMYNVKRGLRNEDGSGVLV
                     GLTQVGNVVGYERLPEGGLKAIPGKLFYRGYDVEDLARDFIKEKRFGFEEVAYLLLSG
                     KLPDKEELSAFKELLNDNMPLEQKTKMNILDLEGQNIMNILARSVLEMYTFDANPDDT
                     SRDNLMRQSIELISKFPTIIAYAYNIYRHSTQGRSLHIRHPHENLSIAENFLHMLKRD
                     FTDLDARTLDLLLVLQAEHGGGNNSTFTVRVTSSTGTDTYSSIAAGIGSLKGPLHGGA
                     NIQVVDMFHHLKENIADWKNVDEIDTYFMRMLNKEAYNKTGLIYGIGHAVYTISDPRA
                     VVLKELARDLAKEKGRSEEFAFLELLEERAIECFAKHKGTKKRVSSNVDFYSGFVYEM
                     IGLPQEIYTPLFAMARIVGWTAHRIEELNFDGKRIIRPAYKNVLDDREYISINER"
     gene            complement(31330..32607)
                     /gene="icd"
                     /locus_tag="ACZPB4_03755"
     CDS             complement(31330..32607)
                     /gene="icd"
                     /locus_tag="ACZPB4_03755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004450 - isocitrate dehydrogenase (NADP+)
                     activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent isocitrate dehydrogenase"
                     /protein_id="HIR1097367.1"
                     /translation="MSKITKKGNHIFVPDHVTIPYIEGDGVGHEITPVSQKIVNAAIK
                     QAYNGTRSIEWKEVLAGEKAFKQTGSWLPDETMEAFREYIVGIKGPLTTPIGGGIRSL
                     NVALRQTLDLYVCLRPVRWFKGVVSPVKEPQKVNMYIFRENTEDIYAGIEWQQGTPEA
                     QKLLKFLTEEMGVKKIRFPETSSFGIKPVSVEGTERLVRAAIEYAILHQLPSVTLVHK
                     GNIMKFTEGGFKLWGYALAEREFADLTFTWPQYEKIKKEQGEEAANTALVEASKAGKI
                     IIKDVIADAFLQNTLLIPEEYSVIATLNLNGDYISDQLAAMVGGIGIAPGANINYNSG
                     HAIFEATHGTAPNIAGKNLVNPSSLLLSSVMMLEYMGWSDAANLITSAMEQAFSAGEA
                     THDLARFMPNGKSLGTKEFGDRIISIIETIKLV"
     gene            complement(32632..34881)
                     /locus_tag="ACZPB4_03760"
     CDS             complement(32632..34881)
                     /locus_tag="ACZPB4_03760"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003994 - aconitate hydratase activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aconitate hydratase"
                     /protein_id="HIR1097368.1"
                     /translation="MVYDIDMLRNFYVNFPRRVDTARERIGGRPMTLAEKILYAHLYD
                     ESSTRLFKRGEDYVNFRPDRVAMQDATAQMALLQFMNAGKEKSAVPATVHCDHLIQAN
                     MGAKTDIDTATKSNSEVYDFLKSVSDKYGIGFWKPGAGIIHQVVLENYAFPGGMMVGT
                     DSHTPNAGGLGMVAIGVGGADAVDVMTGMEWELKMPKLIGVKLTGSLNGWASPKDVIL
                     KLAGILTVKGGTNAIIEYFGPGTASISATGKATICNMGAEVGATTSLFPFDNTMAQYL
                     RATGRDEVASWAEAIGEYLEADMDVRAEPDKFYDRVIVINLSELEPHINGPFTPDAAT
                     PISEFAAKVKANGYPRKMEVGLIGSCTNSSYQDLSRAASIARQAYEDKIPVAAPLIIN
                     PGSEQIRYTAERDGIIGDFERIGATIMANACGPCIGQWKRHTDDNTRKNSIVTSFNRN
                     FAKRADGNPNTHAFVASPELTLALTIAGDLCFNPLTDTLKTEDGKVVKLKEPKGSDFP
                     PKGFEVKDNGYLAPTGKNVVVNIDPESNRLQALKPFAPWNGEDFTDMPLLIKAEGKCT
                     TDHISMAGPWLRFRGHLENISDNMLMGAVNAFNGKTNSVLNQLNNEYEAVSAVAKQYK
                     ANSISSIVVAEENYGEGSSREHAAMEPRFLNVKVILAKSFARIHETNLKKQGMLALTF
                     ANKEDYSKIRENDHISIIGLKDFQPGKPLTAVLLHADGTQESFPVNHTYNDLQIKWFK
                     AGSALNTAH"
     gene            complement(35152..36801)
                     /locus_tag="ACZPB4_03765"
     CDS             complement(35152..36801)
                     /locus_tag="ACZPB4_03765"
                     /EC_number="2.6.1.1"
                     /EC_number="4.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aspartate transaminase/aspartate
                     4-decarboxylase"
                     /protein_id="HIR1097369.1"
                     /translation="MDKKKIHVTREYEKKMSEISPFELKNILIELADESARKSTHIML
                     NAGRGNPNWISTVPREAFFLLGQFALEECQRETELADEMAGAAGVPNRKRIASRFVQF
                     LKKHAQSPGATLLKGTYEYLVTEKGVDENELVYEWAEGVIGDQYPVPDRILKYTEMLV
                     RDYLDQELCDNQPPEGIFDLFATEGGTAAMCYIFDSLQQNFLLNKGDKIILFAPVFTP
                     YIEIPEQARYLFNVIEIKALKMTKDGYHTWQYQEKDLDVLKDPSVKAAFITNPSNPPS
                     YGLTKALMNRIVEIVRNDNPNLMIITDDVYATFIPHFRSMMAELPKNTLCVYSFSKYF
                     GATGWRLAVIALHQDNIYDRMIRELPRDKQELLKKRYSSLSLHPEDIRFIDRMVADSR
                     QVALNHTAGLSLPQQTQMSLFASFALLDAENTYKKRMQDMIHERLHTLWESTGFTLLD
                     DPLRAGYYSEIDMLVWAKKFYGDDFVEYLKKNYEPLDVVFRLAQETSLVLLNGGGFDA
                     PEWSIRASLANLKREDYVRIGEGIASILHSYAQRWKESLDK"
     gene            complement(36814..38511)
                     /gene="aspT"
                     /locus_tag="ACZPB4_03770"
     CDS             complement(36814..38511)
                     /gene="aspT"
                     /locus_tag="ACZPB4_03770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007755302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0070906 - aspartate:alanine antiporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-alanine antiporter"
                     /protein_id="HIR1097370.1"
                     /translation="MEWITNLLQHYPELAIFITLALGFWIGKFKIKKFTLGTVTSVLL
                     VGVLIGQLKIDISGPLKSVFFLMFLFAVGYSVGPQFFRGLKKEGLPQMLFAAVMCVFC
                     LIAPFLLAKLMGYNAGEAAGLLAGSQTMSAVLGVAEDTIGQMNISDTDKSAMVNVMPV
                     AYAVTYIFGTAGSAWLVSDIGPRLLGGLDYVKKACKELEAKMGNNDESEQPGFMPAAR
                     PVTFRAYKISNEWFKEGKSVKQLEEYLDQLGRHLFVERVRINNVLTDVKPDLVLHTGN
                     EVVLSGRREFVIGEENWIGDEVNDIELLDFPAETLPVLVIHKEYVGKKICYLRNQSFM
                     HGVSVKSIRRAGINIPVLAATVIDSGDMLELVGMKSEVNKAATTLGYPDRPTNQTDLI
                     FVGIGIFLGGILGSLAIHFGGVPISLSTSGGALIAGLVFGWLRSKHPTFGRIPEPSVW
                     ILNNLGLNMFIAVVGITAGPSFVTGLKEVGISLFIIGALATSIPLIIGILMGRYVFKF
                     HPAITLGCTAGSRTTTAALGAVEDAVGSETPALGYTVTYAVGNTLLIIWGVVIVLIM"
     regulatory      38597..38794
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            38923..39840
                     /locus_tag="ACZPB4_03775"
     CDS             38923..39840
                     /locus_tag="ACZPB4_03775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016852 - sirohydrochlorin
                     cobaltochelatase activity [Evidence IEA];
                     GO_process: GO:0019251 - anaerobic cobalamin biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sirohydrochlorin cobaltochelatase"
                     /protein_id="HIR1097371.1"
                     /translation="MRKHLLSFFLLVISLVCRAHDGENFVASDLFASLQPGDKAALLM
                     VHFGTTHDDTRALTIDAINQKAKEAFKDVELREAWTSRIVMRRLKARGVEKLNPIEAL
                     EKLKTDGYTHVLIQSTNIIEGIEMESLRKDVATMKSSFKEIRIGNPLLYTPEDYEAVI
                     VAITKNGAKEGATLLVGHGTYTPATAQYAMLDYMLKEKGFKDYSVGTIEGYPTFDTMV
                     AQVKANGTKKVLLMPFMFVAGDHAKNDIAGDWKEELEKKGYEVSVFMEGLGQNPDIQK
                     IFIEHARFMAKHKMIDIVDKKKAYAVEKD"
     gene            39987..42368
                     /locus_tag="ACZPB4_03780"
     CDS             39987..42368
                     /locus_tag="ACZPB4_03780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0015343 - siderophore-iron transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0038023 - signaling receptor activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HIR1097372.1"
                     /translation="MKRVLTILPLTALCISTMQAQHKNEYTNFADTTFNIQEVVATAA
                     RKPRPQITKLDVPMKYLPISINSITASSLELRGIRNIQDAVRFMPGVRFQTSYGAFQQ
                     LSIRGFDHSIMMIDGIRDERSAINNSYPVPDLSCIESIELLKGPASVLYGHSAVGGTL
                     NIVRKSPSEKQSVNARLAYGSYENKEATLGMGGKLVGPVNYYANVNFSDQEGWRDNGN
                     RRFSGYLALQAKMTERDILDVRGGFNRDFYGTEIGLPDLMANDVYNVQTGQLYLHKNE
                     MLPGLDREARYNNESDFMKNHAWNVSTQYTHTFWNGAKLTDRLSYNNDDINYFGTEAL
                     DYLESDDPIYDHYYMKNGQKKYICLDSVYLSFPLRFSHIAKTVANTLELSGKFRTGEI
                     KHTYMGGYSFVALNRTSYSGYNLGDDVQGPGLYSHVSVYDPHSMGYMTSKFSKATVTH
                     HYSNSLYLQDMVEFNEQWKVLAALRYDFFRYMSASATTPTGRREYEEHSSFNMIKNKA
                     LTYRFGAVYLPHPNTSIYASFASFFKPIRTFYQDNVIYVGGDGNRFEPARNEEVFKPE
                     KGYQAEVGLKYQLNNILSANASLFYIRKMNSTATLTNNYQEEVNGETTTMSVIGQVGV
                     QDSKGFDFDVTLSPVSTLALTIGYGLNDSKIREMKEIKDPELIEAIYGNNPDETKQQL
                     NSQEGNWQSNVPNQTFYAYGSYTIPRGVLKNLEFHLSSSYTGKVYRNTSNNSWFDPYW
                     VTDFGMSYLLNNNIHLTFNLNNLFDNNYYNQALGQQMVPSMPRNFQVAISYTL"
     gene            42387..43850
                     /locus_tag="ACZPB4_03785"
     CDS             42387..43850
                     /locus_tag="ACZPB4_03785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HIR1097373.1"
                     /translation="MNLLTKITLFIHRILGTAFSILFLVWFLSGLVMIYHTFPRADRA
                     DKRAKMDILSLENLPSLDQIEKRLPQNERISHVTLNSYLGQTVFHIRTEKGSYDIPAD
                     STERLPVIDWNHIQRVASLWNTSSIAKVDSLYTLDQWIPFGRLKEEFPIYKFHFADPE
                     RHELYISSKSGEVLQYTDKNSRFWAWLGAIPHWVYFTSLRQDAELWIKVVVWLSGIGC
                     VMCIAGIYLGIRDFRLARRRHLISPYKKFWYKWHHILGVLFGLFVLTFCFSGMMSLAR
                     VQDWGLKAKLDINPVQELRKMAPSPLDYPLDYRAVIQAYSGQIRQLEWSSFGDIPFYI
                     VQTDTKDIVVNANKSDGISLLNLRPEEIRSVLSQIHGIGTTADIKLLDAYDTYYISRK
                     RNLELPVWKVSIQDVDNSCYYINPRNGQYRYVNTPSRWNHWMYPALHSLNLKFLVDHP
                     VLWNIVMWGTMLGGTFVSLSGVWLAIKYIRRKARRKK"
     gene            43907..45319
                     /gene="cobJ"
                     /locus_tag="ACZPB4_03790"
     CDS             43907..45319
                     /gene="cobJ"
                     /locus_tag="ACZPB4_03790"
                     /EC_number="2.1.1.131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005788019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030789 - precorrin-3B
                     C17-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-3B C(17)-methyltransferase"
                     /protein_id="HIR1097374.1"
                     /translation="MNKGKIIVAGIGPGSEADITPAVLAAIQSSDVIIGYKYYFRFIT
                     HLLREGTECIDTGMKREQARAEQAFAYANEGKTVCVISSGDAGIYGMTPLIYEMKKES
                     GSEIEIESYPGISAFQKAASLLGAPIGHDFCVISLSDLMTPWELIEKRIHAAAMADFV
                     TAIYNPKSEGRYWQLYRLKELFLQERKPETPVGYVRQAGREEQEVFVTTLADLDPEQI
                     DMFTVVLIGNSQTYLSGNHMITPRGYYGEIKQKKMDTGIGQDIMIRSFRTIEKELKNQ
                     KIPLDKKWALLHAIHTTADFDMENILYADPNAVSTLYNKISGGEVPTIITDVTMAASG
                     IRKGALQRLGVEVKCYLQDERVAEMASSKGITRTQAGIRRAVEEHPTALFVFGNAPTA
                     LMELCDLIRKGKATPAGIIAAPVGFVHVQESKHMVKPFIGIPKLIVEGRKGGSNLAAT
                     LVNAILCFNDAEQLKPGRDV"
     gene            45316..46515
                     /locus_tag="ACZPB4_03795"
     CDS             45316..46515
                     /locus_tag="ACZPB4_03795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional cobalt-precorrin-7
                     (C(5))-methyltransferase/cobalt-precorrin-6B
                     (C(15))-methyltransferase"
                     /protein_id="HIR1097375.1"
                     /translation="MNRFYVIGLDDNMRQYFPPEILEIISSHRVFSGGVRHHEIVRSL
                     LPEKADWIDIKVPLDEVFDRYRSYDGRESIVVFASGDPLFFGFAVTIQNRLPDAQIRL
                     YPSFNSLQLLAQNLLMPYHDMRIVSLTGRPWHEFDRALIESASKIGVLTDREHTPTTI
                     ARRMLEYGYGNYTMFVGERLGNTERQSIRQFSIQAAAMNNFVHPNCLILRKERDGHSR
                     KFGLPDSAFEHLNGREKMITKMPIRLLSLSMLDLINRERFWDIGFCTGSVSIEAKLLF
                     PHLHITSFEIREEGRKLMTENCHRFGTPGIEAIIGDFLSVDLSALEAPDAIFIGGHGG
                     KLVEILMVVSKKMKESGVIVFNSVSDESKALLEEAVRQTGLRISAQTRITIDDFNTIT
                     VNVIYKL"
     gene            46512..48293
                     /gene="cobM"
                     /locus_tag="ACZPB4_03800"
     CDS             46512..48293
                     /gene="cobM"
                     /locus_tag="ACZPB4_03800"
                     /EC_number="2.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046026 - precorrin-4
                     C11-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-4 C(11)-methyltransferase"
                     /protein_id="HIR1097376.1"
                     /translation="MSTISIIPISDSSRVLAERILASYPEAKILPFGSFSKEVFHESS
                     SLVFIGAMGICVRSIAPFAEDKHTDPAVVCIDSTGKYVIPVLSGHIGGANDLSKELAN
                     LLGAEAIITTQSDNANLWALDTLGKKYDWTLIAKDSNAAISTFVNGKPTALLLDIRDK
                     GTDYLERTVPSHVSIFYSFEAIPQQDYELLMIVSPQQYDTSIPTITYIPKVLHLGMGC
                     RKDMQGDPTVVYEHIKDVLRDKRLYPEALADVNTIDLKKCEPVLTLLAYGVMECPFHT
                     YTSEELKDIPVPNPSEKVLEVTESSSVSEASAIYAAHGGPLLVEKQKADLGKGNEYTF
                     AVALDRTACRKGHIEIVGAGPGDPDLISIRGRQMLEKADLILYAGSLVPKELTLCAKA
                     GATVRSSADMNLEEQFALMKEFYDKGLFVVRLHTGDPCIYGAIQEQMNYFDQYGMDYH
                     ITPGISSFQAAAAALYSQFTIPEKVQTIILTRGEGRTPMPEKEQLHKLAQSQSTMCIF
                     LSAGVVEKVQEELLRHYAPTTPVAACYKLTWKDERIYRGQLKDLAKIVKENHLTLTTL
                     LVVGDAIDNRKGLSRLYADEFKHLFRK"
     gene            48293..>49008
                     /locus_tag="ACZPB4_03805"
     CDS             48293..>49008
                     /locus_tag="ACZPB4_03805"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008668682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016994 - precorrin-6A reductase activity
                     [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-6A/cobalt-precorrin-6A reductase"
                     /protein_id="HIR1097377.1"
                     /translation="MILILGGTTEGRVAVRVADEAAATYYYSTKGTLQSIECAHGIRL
                     TGAMNAEEMECFCRDHAIKLLIDAAHPFAQVLHQTIEKVSKCLQIPVIRYERRYPPRD
                     EDLIWCDSYADAIHQMENKGIQRLLALSGVNTLAPLRPYWRSHTTWFRILEREESLSL
                     AEKQGFPQERLVFYREGEDELKLLEQLHPDAILTKESGFSGYFTDKVNAARQFGIPVF
                     VVKRPALPETFYRVYGEDGLR"
     assembly_gap    49009..49108
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <49109..49834
                     /gene="cbiD"
                     /locus_tag="ACZPB4_03810"
     CDS             <49109..49834
                     /gene="cbiD"
                     /locus_tag="ACZPB4_03810"
                     /EC_number="2.1.1.195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-5B (C(1))-methyltransferase
                     CbiD"
                     /protein_id="HIR1097378.1"
                     /translation="GPAINATPRKMIRQELIPLLPSPDSVAIVTVSVPGGEELAKRTF
                     NPKLGIIGGISIIGTSGIVRPFSSDAFIASIRKEASVAKAIGCETLVINSGAKSERYL
                     RSLYASLPPQSFVHYGNFIGETLKIAADLGFKQVILGIMIGKAVKLAEGFLDTHSKKV
                     VMNKGFLQDVAKEAKCEEATVDAINRITLARELWELLAEKEQNRFFPLLLQKCKSYCA
                     PILPDGELTLLLISEEGKVLYQS"
     gene            49987..51216
                     /locus_tag="ACZPB4_03815"
     CDS             49987..51216
                     /locus_tag="ACZPB4_03815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0019867 - outer membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BamA/TamA family outer membrane protein"
                     /protein_id="HIR1097379.1"
                     /translation="MFRYLLIYMACLLFAFSVKAQGISNDTILKEVLMLDGKPMTEKQ
                     IQRYHKQLHKDSIRANKRIWWSILGGPSYTPEASFGVGGAVLASFRLNKNDTISQRSF
                     IPAGFNITLNGTFVFAGAGTLFFNENRFRIYISYGYRNEPSHYFGKGYETIEQIEKSD
                     STTKFHKSSFQLYPRFVWEVRPHLYTGPLFDINFSKSDDINPVMAEDPYFNKFKRDYV
                     NIGVGGLIQYDTRNDVATPSSGMLLSAIAKVYGKYLGGAYNYEMFELEYRQFQQVFRP
                     RSTLAWIAKTQIGVGNVPFTELPSFGSPFDLRGYYWGKYRDKTMAYGILEYRHMFGSV
                     EKYKSGNFWAKCGFVGWVGTGTIGNAPIVDWNKWKFNYGVGLRIQMQPGKNFRLDVGK
                     DPNQKGMAVYMNMTEAF"
     regulatory      51320..51417
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            51412..52260
                     /gene="thiD"
                     /locus_tag="ACZPB4_03820"
     CDS             51412..52260
                     /gene="thiD"
                     /locus_tag="ACZPB4_03820"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HIR1097380.1"
                     /translation="MDKNETYRYPVALTIAGSDSGGGAGIQADIKTFSSLGVFGASAI
                     TAITAQNTQGVRGIQAISPEILRGQIEAILEDFIVDAVKIGMLHNKDAVKVVSETLPS
                     FQQTSIILDPVMISTSGSKLLEDDAIRTIMDELFPKATLLTPNIPETEYLSGIKINNE
                     ADILLAARKLQEKGCNALLIKGGHIPGVETVDRLFINENNPICLVSPTVETFNTHGTG
                     CTLSSAIAAYMALGHSLVEAVRLAKEYMNNALVHGANVCMGKGHGPVNHFFSPSALHK
                     IRWNHE"
     gene            52253..52849
                     /locus_tag="ACZPB4_03825"
     CDS             52253..52849
                     /locus_tag="ACZPB4_03825"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009229 - thiamine diphosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HIR1097381.1"
                     /translation="MNKLVVITTPYFFADEASLIELLFAEGMSRLHLRKPDCKRDELE
                     GLLDNISPAYYDRIVLHDWFTLAEERALGGVHLNKRNPEAPPLYKGSISRSCHSLEEI
                     IEYKPVCDYVFLSPIFQSISKEGYGSGFPLDGLRNAKGIIDDKVIALGGICLQTITKL
                     RDIPFGGVAVLGALWGNDPSLLVADQLIKQFKRLQVWP"
     gene            52840..53568
                     /locus_tag="ACZPB4_03830"
     CDS             52840..53568
                     /locus_tag="ACZPB4_03830"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HIR1097382.1"
                     /translation="MALNYYFGYDENGRVGRRTTGLRPPFGGSNRLMFITHRTPKYTE
                     CDEVRMAIQGGCSWIQLRMKDGIYEDTVRKCATICAEECERIVDFCVNDDLEAAVTCG
                     ATACHLGKNDIPLDIAWEVLKDKLDSNAIFYIGATANTFEDIRLAVERGASYIGLGPY
                     RFTGTKKNLSPILGLEGYRKIIAQCKEAGIDIPIFAIGGITLEDVGPLMETGITGIAV
                     SGAIINAPDPVEETRRFIEEINKY"
     gene            53580..>54100
                     /locus_tag="ACZPB4_03835"
     CDS             53580..>54100
                     /locus_tag="ACZPB4_03835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /protein_id="HIR1097383.1"
                     /translation="MATKKNMRISYPSSEKIYVPGEINKIKVGMRKIKLLDTVTLDEH
                     GERIFKKNNPVIVYDTSGPYSDPKISIDIAKGLPRIREEWYGKRKDVVQLPELTSAYG
                     RERLADASLNSLRFPKRYLPFRAKEGKNITQMYYAKKRIITPEMEYVAIRENQQIEAL
                     GLKSYITPEFVRK"
BASE COUNT        14632 a        11939 c        12190 g        15239 t
ORIGIN      
        1 cccacatgat tacccgttag cttgccattc tcgatctcaa gctcgttggc gtatacatag
       61 tcgatattat atttttgttt aaggaaatta ccgaaataag tgaaacctcc ggaaaggata
      121 gcgatcttga agcccacctt tttcaagata cgcatcaaac ggtctacacc ttctgtgatc
      181 ggtagattct cggcgatctc ctgcatcacg gatacgtcca acccctttaa taaggcacaa
      241 cgctggcgga agctctcgca gaaatcgatc tctccacgca tggctgcctc tgtaatcgct
      301 tttacttgat cgccaactcc ggcacgtatc gccaactcgt cgataacctc cgtctctatc
      361 aaggtagagt ccatatcgaa acaaatcaga cggcgcatac ggcgatacat gctatcctct
      421 tggaaagaga tatccatctc aagctccgtg gaaagtttca tgaactccgc tttcatgcac
      481 tccttgtttt tcggggtacc acgtacggaa aactccacgc tcgccttggg agtacgggca
      541 ttctcgtcca acgggatacg tcccgtgagc cgcttgatat catcaatatt catatcttgc
      601 tccgctacga tccgggaaac acccgcgatt tgcttggccg taagctttcg gcttaatatc
      661 gtgatgatat atcggttctt gccctgcata cctacccatt tactatattc ttgctctgta
      721 atgggattga aacggatatt gacgtctaat tcgtaactct tgaacagtag ttctttcaat
      781 atatcgccgg aatttccttc cgtgctttga aacaagatac ccaatgataa atggttatgg
      841 atatccgctt gaccgatatc gaggataaca gcgttgttct tggctagaat ctccgtaaga
      901 gccgccgtta cacccggacg atccgctcca ttgatattta tcagtattat ttcgtcgttt
      961 tgtgccatat ttgtcattct attaggcaaa agtacgtaag aattatcgaa aaagagtata
     1021 ttatattaaa catttttgct tatatttgtt ttatcgtatt aacgacaaaa tgtttaatga
     1081 gaacctggca accttaaaaa gtcctgaccg gcaggcgaaa tgtatgagaa tccaatttga
     1141 aatcaaggaa aagttgcccg acattatttc tgaaatactt cattcagata agtggctgac
     1201 tttagtgaga gatgagaatc atggattgcg acgtgtgacg attaaagatc cctactttga
     1261 ttcagaggca tgcgtcgata tctgggagca tgagattcat gtaacgacag cttggtctaa
     1321 ctacacctat cgaatctatc aaaaaggtaa ttctgtttgg tgcgaataca ttggcgctta
     1381 tagaggattg ctggaacaaa accttttgcc gacgatgact ccgaaagaaa atattctgga
     1441 ttcggaagta ttgaacagtt ctttgtttgg tgacagaaag gagaccttga gaaattacag
     1501 cgcggaaaac cttaagctga agaattttag gcgggataat ttcgccgcgg aatatcaact
     1561 ggcttctccg caagaccatc ctaagatcgt atatgatgag tttattaaag aaggggttcc
     1621 aattccccct cctgaagata gaaaagaaaa gtccggtaat taataccgga ctttttttat
     1681 ttgaggatca tcgcatgata cccgaatcct cgtcactatt ccaaagtttc ttattggcct
     1741 ccttgaactt gcggccgaag tcaaaattcc aagagaaggt tagcatcaac attcggctga
     1801 agtcgttcgc gtacatgttc gtacggctgg gagcgtaagc gttccgattt tcctctaccc
     1861 gtttgtactg gctggagaaa ggcatcatca atccggctcc aacggcgaat ttaccttgat
     1921 tgtaccggaa cataaacata tggatattct cgccgccatg caataattcg ccgacaaacg
     1981 tattatagct actttgtatc tggaacatag ccatgaattt cttgtacata gccatgacgg
     2041 aagcccggta ataccaattg ttataggtat gcgagtaact atttccttcg ctgatataac
     2101 gattgactcc acctgtcacg gataggctta tgatccgctt gatgataggg ccgacacgta
     2161 atgtcaagtc accgcttagt ttctgccatc ctttttggtt atcggtaatg cgaatgaact
     2221 tattattttc tcgtatcact tcctccatga tctggtccgg gctattactg taataaaagt
     2281 ttaagtctcc ggtgaatatt ccttttttat atagataatt ggcttgcatg tcataactct
     2341 tatagggttt cagataagga tttccccggc gtatctgtag cgtatcgata tattgctcga
     2401 tggcgcttag ttccgatagg ctaggtgaga cattatttac gctaccgttt acccggaaat
     2461 acatattatc cgtaaagtta tattgtaagg atacctttgg gcggaacgta taatattgat
     2521 aatcttcctc gccttcttgc ttgaaccatg agcgggagac acctattccg gcggtataat
     2581 tcaacttctt gacacgtccg ctgaattccg tatagagata cgtctccgac tgtttcatct
     2641 tggttcgtcc tccaaccgtt ccgctgtagg tgttatccgt ccacgattgg gtgtgtttca
     2701 atcctcctcc caatcgaccg gcctcgaatt gccgttcgta gattccctcg ccgatgatgg
     2761 aatatttgtc tccgtccacg ttcgacaaga tatccgataa gaggatatcg tttttccatt
     2821 cttgatacat ttggtttgcg ttcgtatgta tgtacgtacc taccatatta agtatcaatg
     2881 tctgcttatg tggtaaggag cgttggtaat aaaggtcgag ggaaggacgt ttggttgagt
     2941 tgctattcgg attccaagcg tatgtcttat cctcgggatg attgtttgca tacaggttct
     3001 taccgttact acctttatcc tcgtccgata agaaataacg tagcgtggca ttgaaataat
     3061 agtggtcatt atctaccaga ttataattaa gggagaggtt atgggaggtc tcggacattc
     3121 ttcccggaag accttccgag gtgcgttcca gcgtttcgcc attctcaaag cggaaggtct
     3181 cggttccttc cgtccagata tgatacggat tccggtaacg gacggcgtat tgcaatccga
     3241 actccgattt cttatgattg aacttcgccg atacctgatc gtctccaaaa gaggtggtcg
     3301 gtgaattact aaggtctaga ttaacagaac caccgctcgt ttctctccgt acaatgtaat
     3361 cgagtacgac agaggcatta ccgtagcgta agcccggatt atcatgatat tctacccgga
     3421 ttacctcctg tggcgataag ccccggatat cagacagctc caccttgata ccgttgatgc
     3481 agaattgaat agtcccttca ttcgatagcg atacgctatt ccggatcggg tccacttcca
     3541 aacggggacg catcaaggcg ttcaatagat tgatgccatt gctggaagcc gctttttgct
     3601 cagaggtagg gaacgtgatc ttacggtccg ccgtattgcg gatagcggaa gcgttgaccg
     3661 tgacttcatc taaggatata gaggaggatg ccaatgagat cgtaccgaga tctataggct
     3721 gggaaagtcc cagcacggag actaccgagg tcttgtaacc tatggaggaa acagatactt
     3781 gataatctcc ggccttgact ttctcgatcc ggaaaagtcc tttactatcc gtcgtcgtcc
     3841 ctgtgataaa tgcggaatcg gctgtttgaa gcgtgatatt cgcaaactca agaggagact
     3901 tgtcggatag atcaatgact ttccccctga tctgtaattg ctgtgcccgg ataccccaag
     3961 aaaaagatat aagaagggcc gccataatga tttgtttcat tatagtacga tttaatgatt
     4021 aagaaataat gtgtgtatgt gattgttacc tagtccaaat ctcttctccg ttcagacgga
     4081 tcttctggat attgttgata cggatatgca acgtgagatt tttatcttgc ccggcgcccc
     4141 tcgccccgct aaccaataat agagaatcgt ggcggctgac ttccggcaaa taccgtttca
     4201 ttccctcgta atagagtaac gaccggtcct ttgcttccag tatttgcccc cgaggaaatt
     4261 cggaggcggt tctcgtatcg acttttatgt tttccgcttt caactccgga ttatctatct
     4321 ggataatctg aaacttttgc gtgaaacctg taaggcattt ttccgacgta aactgggcaa
     4381 cgccgaaagt gagggctgga acgatatata atgtccctat caaggcgata aatacgcaat
     4441 tacttttttt catgattgtc tttatttaat ggtagatata tataatgtat aggctttcgt
     4501 aagctcgtcg atacctacat ctagcaggtg catctccttg aagacggcgg gaagtacctc
     4561 ttccacgaac tggttatggc gcatctcacg gattttttgc tcggcgtcgg aagcgacgaa
     4621 gtagccgatc ccacgcttgt tgtaaataat atcgttggct tgcaggcgct cgaaggaacg
     4681 catgaccgta tttggattta cctccatctc taccgccagt tcccgtacgg acgggatacg
     4741 gctatcggct ttgtaattac cactcaatac ccggtcgcaa atccgctcgg ctatttggat
     4801 aaatatggat tgattcgtat tgtagttcat cttagttcct tttctttaag ttttagataa
     4861 gcgacgtata agaccacgag ggtagcgatg agaaatgcgg gtgtaaaggc aaagcttagc
     4921 caatacacgg cggtataaaa cggtgaagat tcataacaaa aactattcat acccggctgg
     4981 atattcaaga tgtttatgca tagatagaca atccctatga tagaagcgat tatcaatata
     5041 tatccaccac aagcgattcc taaagcatac ttcttgaatg tgacgtaaga gaggaacatc
     5101 aaggaaccga caaacgccag catggtgaaa tcttgcaagg tcatgataat gtccttgaat
     5161 gctacaggct gtatatgaat gagcattgag gctattcccg tcccagtcca gaacgtgact
     5221 tggtatgtta agaataccac gatgccttcg atcaagatag cggcaaattt ctcttggttg
     5281 ctcgcgggaa gcgtcaagaa taatcctcta ggacggtgta tcattaagtt tacgtagcta
     5341 cagaaagcga taaaagttcc taatgatccc aatacatata atgtaaaggt acggaatctc
     5401 gtatcccata aaatggagga taataggaaa aagaagagga ctccgaggat gaccaacacc
     5461 ccataagcta atttcttctt attctctatc caatctttgc gaagtaaaag attgatgcgt
     5521 tgtatactga aatctgtttt catatctatg tgtattttag gagttcatga ttctttggat
     5581 ctctttggga taagttatcg ccgcgttaaa gagcaactct aaggatacgg ccgtctcttc
     5641 cttgccatcc cttgcggtga cgcctattgt cccttgcggg gtaggctcgg aataaagagc
     5701 tttctcttcc ggcaggagcg gtccgaaata aagtttctcg ccgatctcgt tcaacgtctt
     5761 attcaatagg atttgccttt ggtctaagat caataccgtg tcgatcaagc tttccagatc
     5821 cctgacctga tgcgtggaga taataaccgt ctgattgtca tctatcaaag aggctaccag
     5881 tctgcggaat gtcgccttcg agggaatgtc cagcccattt gttggttcat ccattagaag
     5941 caggggcgta tgagcggcca gtgccaaggt tatcgccacc tttttccgtt gtccttgaga
     6001 cattttcgac aggcgatcgg atagattgat ctcaaacgat tctacgcaag ccttgcagat
     6061 atcgtcccta aatgtcggat aaaaagccgc gtacatcttt atatattcta tggcggtgac
     6121 ctcaggcatg gagatttcct ccggcaataa gaagatctgt tgcaagaaac gagcgtttct
     6181 ctcggaagga atttcttcca atgcgaggca agaaccttga tccggaaaga tctgtccgct
     6241 tagaaggttt agaagcgtag tctttccttc accgttcttt cccaataagc cacagatgtg
     6301 tcccgatcca acctcaagat tgatacgatc aagtacctct tttttgcggc tatagctgaa
     6361 tgagagttct tttaatgtaa tcatatgttt tgctgcttta gtgtattagt ttaatagtac
     6421 actgtaaatg tagtggaagt ttttgaataa acaagaggga agggtatttt tttcctttta
     6481 tttttcaaga tggcagtaca aggtgattaa agggaatctc ttaatgctat tagcctcttt
     6541 tccaagaagg attagcggtt tgctcttgaa gcattgctaa tttttcagtt ggtgcatgat
     6601 cttctaacgg ctgttggaag atcatgcacc aactgttaga tgattatgca acagccgttg
     6661 gataatctat acttaaagat gaaatcgcta aggattccct gttatcggtc taaaggtagg
     6721 ggagcgggaa gctaatgatt cttgatgatt ttgcggttct ctcggggaga aaaaggtact
     6781 ctacttctaa atttatgttg caaaacagtt aattttttat cgatgtgtgc gctaaaacat
     6841 ataaaaaagc ttgctaattt gcagaaaatc gctatataat ttggtggaaa gaagtatttg
     6901 gctttatatt tgcacccgtt aaagacaagt aagtgtctct ttagcgaaag aaacatgctt
     6961 gtttacgatc ctgaaaatca ggagtcggga gtttatcccc cgggagattc ccccgattaa
     7021 gtttaacgta aaattgaaaa tatgaaggta agagcttatg ttctcatcgc atcggtagcg
     7081 ttattaggaa tgtctgccgg ttcgaaaaag gcgaaactta ccgagggtgt gaaccccggt
     7141 gatctagctc cgagaataga gtttttggga aacgacgcta aagccagttt ccacaaccaa
     7201 ttaggacgtt atacattgct caacttttgg gcggcttacg atgcggaatc gcgggctcgt
     7261 aacgtgcaat tggcgaatga ggttaacaag tttggtccgg acaaaatcgc gatgtgttcg
     7321 atctctatgg atgagaaaga atctattttt accgagacgg taaagattga caagttggat
     7381 ctgtcaacgc aatttcacga aggactgggt aaagagtcag agttgtacaa gaagtatgat
     7441 ttaagaaaag gtttcaagaa cttcttgatt aacgacgaag gagtgataat cgccgccaac
     7501 gtcacaccgg aaaaactgac cgagattctg aaagcaattt aatcagtatt atttagcaaa
     7561 gagggctgtt ccacttcaag atgggacagc ctttttttat cgattcacga gttttcgttt
     7621 cgagatgatg aaatagcatg tatagtctga gaaggaaatg tacactttct ttttaagtcc
     7681 gtgtttatta ttaactcttt ttgatttatt aaccctaatg gatagggtga ttgagaaggt
     7741 cctctgtctt tactgtaaat gaacaactaa catcctatat ataatgagat ctatactttt
     7801 ctttatttgt ttgatcttta cctttgaggg acaggcgcaa gaggtagaaa aatcccatat
     7861 gtggaaagta gaactctccg gtgccttgaa taataattca gcatgggagg tagagccatc
     7921 tgttacttat ctaccgattc cttatgtggg aattactatg gggttgcttt tctgtaatac
     7981 gattgagaaa gatagttata cggggttttc aagagataat cagtggttct gggattcaga
     8041 tgagagtaat ccgggctgtc atttctttgc gttacgtccg gccatccagt tagtaactcc
     8101 cacttttaaa ttcgggaaag acaaggatac gggactctct ttggtcgttt cacctggatt
     8161 aaccattcct ttgcctgtca atcaagagtt taatataagc tatgttccaa acactcccgg
     8221 ggtatggata cctcaaaaat tcgatcatat aaagaacaag ggaggtaaat cgttatttta
     8281 tcatattaaa agtatgttga gccttgatat agaccagcgg tatatattct ctttggggta
     8341 tatattctcg aattttgatt tatatagtgg agggcgaaac ttcgttgtag agggaaaaag
     8401 gcttagtatg ccccggattc gttttatgca ttcgttcttt ctaagtattg gatatcgctt
     8461 ttaaatcgtt tcatacattg tctttctcgt ttagcccaaa aagggagagc tgtttttaag
     8521 gctctccctt ttgcataagc ttatatataa taatgtatag gatttatcga attgcttcta
     8581 cttcttccgt acgcaaaggg atcttctttc ctaatagacg agcgccgttc tcggtaatca
     8641 gatagtcttc ctcgttacgt atgccactga aatctttata tgtaaacaac ttctcgtaat
     8701 tgatgaattc ggtgaacttg ttctggcctc tccataaatc cattaattcg gggatgaagt
     8761 atacgcccgg ctcgatggtc aagacaaaac ccggttccag cttacgtccc aagcgcaatg
     8821 acttacgtcc gaattccgta ctcttcggct gtccgtcata accaacgtat acctctccca
     8881 gattctccat atcatgtaca tccaatccca tcatgtgacc taggccacaa ggcataaaca
     8941 tggcgtgagc accggctttt acggcctcca tcggatctcc tttcacgaaa ccaaggtcct
     9001 ttaaaccctc catgatcact ttacaagaca actcatatac atccacgaaa ggaatacccg
     9061 ggcgcaaagc cgctacggca gcctcatggg cggctacttg aatatcatag atgtcttttt
     9121 gacgggtcgt gaattttgag tcggccggga tggtggacga catatctccg gcatatccca
     9181 tctcagtctc ggcaccggcg tccaataaca gcatatcacc gctcttaatc atatgactat
     9241 gatcatggtt gtgcaaagtc tgcccattga tcgtggcgat gatagggaag gagagctggt
     9301 aattgttggc gaaagctact tccgcaacgg cagccgctac atccgactcc cggattcccg
     9361 gacgtacggt acgcatggca gtcaggtgca tatcggcggt tacgatacag gctttctcga
     9421 tctcggcgat ttcttcctcg ctcttataat tccgttggtt tacgacaccc atgatgaaag
     9481 gtacggaagg tttctccgca ccgggtacga tacccaacca ttggaataac ttgatctggt
     9541 gttccgcacg atacgtcggc agataatgga ttggctggcc tttttgctgg gcattcttca
     9601 agtatgtctc gatctccttg aaaggacgga cctccttgat acctgcggcc tcgctcttct
     9661 cttttagggt gggctgcgta cccatccata caatcgcgtc tatagtcaac tcatcgccaa
     9721 agatgatctc cttatcgtta tcgatatcga tgatagcgga taacccggcg tatggcaatc
     9781 cgaagaaata caagaaggta gagtcttgac ggaagtgata cgtattatcg gcgtagttca
     9841 tcccactctc gtcgtttcca aggaatagca acaaaccgga acctatggtt tgtttcagct
     9901 tagcccggcg ggccatataa gtttctttac tgaacataag gattattttt tgttagtgta
     9961 ccaaagatag taattaatgt aatatactag gccgacattc gaaattattt cttacattag
    10021 cccatgtaaa atgtaacctc tggtacctta tgaagattca aagaattcaa gaacttaccg
    10081 atgcctccat cgtctgtggc tcagagaaac gggagaacga tgtgcagtgc gcttttgcca
    10141 gcgatctgat gagtgacgtg cttacgctgg attgtggtga tgtgctgttg gtgacaggac
    10201 tttgtaattt gcaaacgatc cgtaccgcgg agatggcgga agtttcttat atacttttcg
    10261 tgcgggggaa gaaagtaacc ccggatatgc tggagctggc tcgtgagaac aatatggttc
    10321 ttctggagac ggatcattct atgtatcata cggtcggaga gctttatagc gcggggctcc
    10381 ttcctatata ttgagaaagg aggtcgtgag atatgctatt taagtttgag ttggagggcg
    10441 gtaatttctc gaaggcgggt tatgcgtcta gccagataaa gaaggtcttg aagcaattgg
    10501 ctatcgatcc ccggatcatt aagcgggtgg tcgtggcgct ttatgaggcg gaggtaaata
    10561 tcgtggctca cgcttggaga ggaacggttg tcgctgaatt ggacgctgat aaaatatctt
    10621 tggaactgaa ggatgaaggg cccggaatcc cggatatatc gctagctatg cgtgaagggt
    10681 attcgacggc atccgaggcc gtgcgtgaga tgggatttgg tgccggaatg ggacttccaa
    10741 atatgaagaa gaacgtagat gaattaacga tcgagagcca agtagatgta ggtaccacgg
    10801 tacgtatggt cacatggttt aataaagaag gagcgtagac catggaggaa gctaattttt
    10861 atcatgcctt gaagattgac aatgaccgct gtataggctg tacgcattgc atgaaagagt
    10921 gccctacggg agcgatccgt atccgggatg gtaaggcttt gatccataag gattggtgcg
    10981 tggattgcgg cgagtgcttg aaatcgtgcc cgacagaggc tatctatgtg gagcaggatg
    11041 acttccagcg tatatttgat tatagatgca gggtagcgtt gatgcccacg gtatttatcg
    11101 ggcagttctc aaagtacacg accgagaagg aaattatcag tgccgttatg gaactgggct
    11161 ttacccatgt tttccaagta gagtttaccg ccgatatgat ccataaggaa atggtacggc
    11221 agatggaaaa cgccgaggaa aaaccggtga tcagttcttt ttgccccgct atcgtccggt
    11281 tgatacaagt ccgtttccct gcgctggtgg ataatatctt attggtgaaa gcgccggtaa
    11341 acgcctcggc cacttattat cataagatat tggaagggca aggtgttccc tcggaagaga
    11401 tcggtatctt ttatgttacg ccttgcgcgg cgaaaatcgc ggcgttgaag ggagcggaag
    11461 gttattcatc tacgatcaaa ggcgtgataa atatggatac cctatataat aaggtatacc
    11521 atattcttaa gaatcgcccg agaggatatg agccggaatg tgagcttcct ccgccattaa
    11581 cgaaaaaaga gatgcgatgg agccagacag gaggggaggc caaacatttc tccggtcgtt
    11641 gcctcgcgat cgatgagatc cataatgtga tcgatttctt ggaacgaatg gaaacgacca
    11701 gcgaggtacg taacgtagac tttctggaac tgagggcttg cgaccgtagc tgtgccggag
    11761 gtgtattagc cgtagcgaac cgtttcctca cggccgagcg tatcatgaag cgatccatga
    11821 accgggataa agtaccgatg atatacgccg ccgataattt cgaggcttta tcctatttga
    11881 ggcagcatat tacgatccgt ccggtgcaac cgaatcccaa acggttgtac gatggaacga
    11941 tcgatgagat gctgaagaaa atggagcaag tgcggaaatt gatgtgctac ctaccgggaa
    12001 tcgattgtgg cgcttgcggc agcccgaact gtcaaagctt ggccgaggat atcgtacgcc
    12061 acgaggctca attcagtgat tgcgtattta tgcaacgtaa tatggagaag cacggtaaac
    12121 tagaccaaga gcatgccttc cgtatcgttg agaagacatg ggggaaagat cgtttaaata
    12181 aggattgtta taagaaagga gctaaatatg aaggtttgtg atttagtgaa gatgttgaat
    12241 cttactgtat tttgtggaga agagggcctt gatacagaga taaccggagg ctatacgagc
    12301 gatttattaa gtgatgtcat gggacatatc gaggagggta tgctatggat taccatgcaa
    12361 acccatcaga atatactggc cgtggctact ttaaaagacg cctccgctgt attgatcgtg
    12421 aacggaacct ctccggatga tgagacctta caaaaaggta gggaagaggc tgtccctctt
    12481 ttaggaacta cacgctccgc gttcgaggct tccggtatga tttaccgctt attacagaat
    12541 gagaatggat gaaacagtat ttagctgatt tacatatcca tacttgcctg tcgccatgtg
    12601 gcagtctgga aatgagtcca tcggagatcg tgcgtcgttc cttagcgaaa ggtttggatg
    12661 ctattgccat tacggaccat aatacgacct tacaatgccc ggagattcaa tcccttggcg
    12721 agagattcgg actaagggtc tttgcgggcg tagaagttac gacccgtgag gaagcgcatt
    12781 gtctggttta tttcccgacc gatgaatccc gtaagcgatt ccaacgatat ttagaagagc
    12841 atctccctcc aattccaaat gatccggaac gttttggcga tcaagtttgg gtgaatgcgg
    12901 agaatgagat tctaggagaa gtaccctatc ttttgctctc cgccttggat caaagcgtaa
    12961 accaaatagc cgctcaagca cgtaaggtgg atgctctatt tgtagccgcc catgtagaac
    13021 gtccgtcatt cagcttgatc agtcaattag gttttataga cccctgctta tctttagatg
    13081 ctattgaata taataatcag caaagataca gtaagttatt gtctattcac gggtatttga
    13141 aagagcagac tcaatactca gcctcggatg cccattaccc cgaacaaata ggtactcagc
    13201 cctccatttg gcaaacggag gaattaacct tcgatggctt acgaaaggct tttgatcaaa
    13261 aagacaatca cttaattttc gcctctcatg gataatctct cgtttcatat cacggatata
    13321 accgctaata gtatcagagc aaaagcttct gatatagaga tagatataca gataaaggac
    13381 acatccatat gtattcgtat cgcggataat ggctgtggta tggatccgga aacagtctct
    13441 ctgatccgta atccgtttta tacgactcgc acgacacgaa aagtgggtct aggcttacct
    13501 ttcttgatac aaaacgcgga gcaaacaggc gggaatgtgg aaatatcttc catacaggga
    13561 aaaggtacgg tagttgttgc ttgttttgtc tcatctcata ttgattgtcc gccttgggga
    13621 gatttggcgg gtacaatggc tatgcttata ggcagtaatc cggacataaa cattcatttc
    13681 tcatatcatt cagatctggt ttcatttgat atcagtacgc tagagcttaa agaaatccta
    13741 gaggacatgc cattaagtca tccgaaagtc atgctttatt tgaaggagtt aatagcgaat
    13801 caaatagttg cgtcaagctg aattaatctt ttcatatagg tgatctgatc ttttcacagc
    13861 tgtgatacga tcttttcaca tccatgaaac aaacgtttca cagccgtgaa aagatctgtg
    13921 tctttactca aagcagctac aagctttgct tgaatgcact aatttatcct tatcttgcta
    13981 ttaattttat aattcccatt atgtttaata gtattatgaa cgatcaaaaa atgactactc
    14041 tgcgatacat gatacacaaa taaaaaaccg cctagtaacc ttatattact agacggttcc
    14101 atttattctg aaagaagaaa ttacttattc atctctgctt caatagcatc gaatttatca
    14161 cccatattca agttgtagta aatacctctt aaagcggtca tatattctct ttcttctggt
    14221 ttcatttggt gagctttctc aaagtaagga agagcttgct taaagaattc cttagctttg
    14281 cctaattcct cttgatattg ttttgcgtcg ttgatcatat tagcctcacc ttgcttgttt
    14341 acaccttggt tataatatac acgacctaag ttagagagag attcgatata gtcaggattg
    14401 atcgccaatg ctttcttgaa atactcttca gctttagcgt aatctttcaa accagtctca
    14461 taaacacggc ccattacatc gtaaagctgt ggattgttgg aatccttagc gatagctgtg
    14521 ttcaaatatt caatagcttt ctcatttcta ttagaataga tgtaattgtt tataaggctc
    14581 attaagaaat actgttcctc agggaattta ttcaaacctt cttccaaagt cttctctaaa
    14641 ttcacggtat ccttagcttg ctcatactca tagcataagt attgatatac ctcgcttgct
    14701 ctataatccg tatttttagc acgctctaac gctgcgatag ctttttgaga atcgccaagt
    14761 tgggtcgctg ctacagcggc atagaactga actgtcatga agtttgaatc tctttcagcg
    14821 acagcctcac ctttaaacat tggcatatca gatattttca ggtattgctc gaagaaatcg
    14881 taagctttgt tataatcttt ctgatcgaaa tagtaagcac caccattgat gtaatatacg
    14941 tggtttgctc ctaggatacc tttgatatct ttcgtgaact taggtttaat ttttcctttt
    15001 tcattaggaa gttgatctaa ctcatatgct ttctcaaagt atggcaaaat actacccaat
    15061 gcctcgtaca taacaggctc gtccggttgt tggcccaaga cttgtttagt tctttcgttg
    15121 ctgaactgtt gatcctcgat aaaaccggca acataccaag ttttagcgtc atcctttgtt
    15181 tcagggtttt ccaaagctcc tttaataaga gttctggctt ccgagaaatc aggagttgtc
    15241 cccttagcta tactttgagc ctcatttaca gcttttttct gtgcaaaaga gaccgatgct
    15301 gcgacacata gtgccactgt taataatact cgtttcattg cgatagtaat tttgagatta
    15361 atatttctat ttgtttaaaa ttattcagtt atttcttcgt tatcattttg ttcgttatcc
    15421 tcctctgatt ccggtagatc aacatcggta cctagactag cttgattctc actcaactct
    15481 cttccctcat tctcttgtct ggcttcttgt tccgcttttt gctcggcaat ctcctcttca
    15541 ctctcagaca atactttaca tacagaagcg atttcgtcgt tgcgcttttc tagattaatc
    15601 aaacgaacac cttgagtagc acgtcctatt acgttcaaat cggccacttt catacggata
    15661 gcgatacccg acttattgat aatcattaaa tcgttctcgt ccgtaacatt cttgatggca
    15721 actaatttac cggtcttctc cgtgatatta atggttttta cgcctttacc gccacgattc
    15781 gttatacgat aatcctcgat agaggaacgt tttccatatc cctgctctga tacgacgagt
    15841 acggtctctt tttccttgtc cttgatacag atcataccaa cgacttcatc ggtattatcc
    15901 tcgtccaaag tcataccttt cactccggaa gccgtacggc ccattacacg taccgcgctt
    15961 tcatggaaac ggatcgcccg gccattacgg ttcgctatga tcacctcgtt gttgccattc
    16021 gtcatacata cttggatcaa gccatcgtct tcacgcaatg taatagcgtt cacaccgttt
    16081 tgacgaggac gggaataggc ctccaacaag gtctttttga tcacaccttt cttcgtacag
    16141 aataataggt aatgagaatt aatgaattcc gtatcggtgg ttaatttctt aacacgtata
    16201 aaggcttgta ccttatcatc cggctcgata ttcagaagat tctggatcgc acgtccttta
    16261 gcgttcttag ctccttccgg aatctcgaat accttcaacc aataacattt accttttgcc
    16321 gtgaagaata ataaggtcgc gtgcatggat gccggataga tatactcaac gaaatcctcg
    16381 tctctagtct cggaaccctt cgctcctaca ccaccacggc cttgcgcacg gaactcactt
    16441 aacggggtac gtttgatata tcccatatga gatacggtaa tgatcatctc atcatccgca
    16501 tagaaatcct ccggatttaa ttcctcagag gcgtaaacga tatccgtctt acgttcgtcg
    16561 ccaaatttat ccttgatttc caataattca tctttgataa ccttcataca aaggtcctca
    16621 ttctccagaa tctcattcaa ataagcgatc aacttctcga tctcctcata ttccgcacgc
    16681 aatttgtctt gttccagacc tgtcaactga cgaagtctca tctcgacaat agcacgtgct
    16741 tgaagctcag ataaagagaa acgttcgatc aaacgctcga tagcctcttg cgggctcttg
    16801 gaagacttga taatcgcgat tacctcgtct atattatcgg aagcgatgat caagccttcc
    16861 aatatatgag ctctctcttc cgctttcctc aattcatatt ttgtacgccg gataacgacc
    16921 tcatgacggt gctcaacaaa cgccttgatt aagtctttta agttaagcaa cctcggacgg
    16981 ccgttcacca aagcgatatt attaacgctg aatgaggatt gcagagccgt aagcttatac
    17041 aatttattca gtacgacact cgagttcgcg tcacgtttca cgtcaactac gatacgcata
    17101 ccgctacggt cggactcgtc attgacattg gaaatgccat cgatacgctt ctcgtttact
    17161 aggtcagcga tatacttgat caactcagcc ttatttacca aataaggaat ctcggtaata
    17221 ataatcttct catgattatt ctccacctca atctcggctt taccgcgaag gatgatacgt
    17281 cccctacccg tctcgaaagc gtctttcacg cctgcgtagc cataaattgt agcgcctgta
    17341 gggaagtccg gagccttgat atattgcatt aagccttcta cctcgatatc tcccttggca
    17401 tcgatataag cgatacaacc atctaatacc tcgctcaagt tatgagtcgg catattcgta
    17461 gccataccaa cggcgatacc cgatccacca tttacaagta agttaggaac acgagtcggc
    17521 aatacggtcg gctccttcaa cgtatcatcg aagttaagct ggaaatctac cgtgtcctta
    17581 tcgatatccc ggagcatttc ttcggcgagt ttactcagtc gtgcctctgt ataacgcata
    17641 gcggcaggac tatcaccgtc cactgaaccg aagttacctt gtccgtctac taacggataa
    17701 cgcatagacc atgtctgggc catacgaacc atggcgaaat atacagacga gtcgccatgt
    17761 ggatgatatt tacctaaaac ttcaccaact attctcgcag attttttata aggtttgtcg
    17821 gatgtgttac ccagttcatt cattccaaat aaaatacggc ggtgaaccgg cttaaagcca
    17881 tccctaacat caggaagagc acgtgaaaca atgacagaca ttgaataatc aatgtatgcc
    17941 gatttcattt cctcttcgat gttaatctta ataattctgt cttgatcaac catttagttt
    18001 tatattaatt acactcaata tctcacctct gaaaaattgc actaaggtaa ggtttttccg
    18061 tatactacga aagaatttgt cttgaaattt tgcgcctctg ggcttttcaa ggcttattaa
    18121 ggaataatgg cacgaaattt gatgatagtt ggaatagatt atgtaacttt gcgtaatcag
    18181 tacatatata atatagtatg aaaaattatt cgaaaagatt gattgacgtg attgagtata
    18241 gccgtgaaga agcggctagg ctccagaata gctatatcgg gccggaacat ttgatgctag
    18301 gcatcatccg ggaaggcgaa ggcgaggcaa tgcgtgtctt gcgagagcta cataccgatc
    18361 cgatggatat taaacgcaag attgagcaag aaataaagaa tacattcgat tctgaggatt
    18421 ctgtccagca tgagatcgct ataagtaaga ctacagaacg tgtcttgcgt atgagtatgc
    18481 tggaatctcg tttattcaag gaagatgaga ccgatacgga acatcttcta ttggcgatat
    18541 tgaaagagga gtttaatgtc gctgccaagg tgttgaacga tgcgggtatt acttatcgtt
    18601 ccgcatataa tatattagta agcggaaccg gtttgaataa tatggaggaa ttcgacgaga
    18661 tcagcgacgg atatacggat gatgacgaag atgacgagga cgaaggtttc tcctctcgtc
    18721 gtgaggcatc tcgcccctct tccggtactg gagcgggagc cgctcaaccg aaatccccta
    18781 atgatacacc tgttctggat aacttcggaa cggatatgac acgtgccgcc gcagaaaacc
    18841 gtctagaccc gattgtggga cgtgagaagg agatcgagcg tttggcccag atattaagcc
    18901 gtaggaagaa aaataatccg gtattgattg gtgagccggg tgtgggtaag tcggctatcg
    18961 tagagggatt ggctttacgc attattcagc gtaaggtttc ccgggtgtta ttcgataagc
    19021 gtgtgattag cttggatatg gcttctattg tcgccggtac gaaataccgc ggacaattcg
    19081 aggaacgtat taaggctatc ttgaatgagt tatcgaagaa cccgaatatc atcctcttta
    19141 tcgatgagat tcatacgatt gttggcgctg gttccgcttc cggatctatg gatgcggcga
    19201 atatgctgaa acctgcgttg gctcgtggtg agattcaatg cattggcgct actactttgg
    19261 atgaatatcg taagaatatc gagaaagacg gtgcgttgga acgtcgtttc cagaaagtga
    19321 tcgttgatcc gactacggcg gaagaaactt tgcagatctt gcgtaatatc aaacctcgtt
    19381 atgaggagca ccataatgtg atctatactg aagatgcttt acaagcgtgt gtaaaattga
    19441 cagaaagata tatcagtgac cgtaatttcc cggataaggc gatcgatgct ttagacgagg
    19501 ccggttcccg tgtacatata tctaatatca ttgttccgaa aagtatcgaa gagcttgagg
    19561 caaagatcga ggatacgaag aatgagaaat tagcggccgt gaaatctcag aactttgagt
    19621 tagccgcaag tttccgcgat aaggagcgtc agtatttatt gcaactggag gccgcgaaag
    19681 ctaaatggga acaagagctt caagaacatc gggagaccgt tgatgaagag aaggtcgctg
    19741 aagttgttgc catgatgtct ggtgtgcctg ttcaacgtat cgctaaggca gagaatgtca
    19801 agcttctgga aatggcggac gtattgaaaa gtaaggtggt cgggcaggat gatgctgttc
    19861 aaaagattgt aaaggcaatt caacgtaacc gtgttggctt gaaagatccg aataagccga
    19921 tcggaacttt tatgttccta ggaccgacgg gtgtaggtaa aactcacttg gccaagaagc
    19981 ttgctgaata tctatttgat tcggcggatt ctttggtacg tatcgatatg agtgaatact
    20041 tggagaaatt cgctgtttcc cgtttgatcg gagcgcctcc cggatacgtt ggttacgagg
    20101 aaggtggcca gttaacagag aaagtacgtc gcaagcctta ttcggtggtc ttattggacg
    20161 agatcgagaa ggcgcatccg gatgtattta acttgctgct gcaagtcttg gatgaaggcc
    20221 gtttgacgga tagtctgggt agacgtattg atttcaagaa tacgatcttg atcatgactt
    20281 ccaatattgg tacccggcaa ttgaaagatt tcggccgtgg cgttggtttc aatacccaga
    20341 tggctggtga gccggataag gatttctccc gtagcgtgat ccagaaagcg ttgaataaag
    20401 catttgctcc agagttcttg aaccgtgtgg atgatatcat tatgttcgat cagcttgata
    20461 aagccgctat tcataagatt atcgatattg agttgcaggg tctgtatcag cgtgtatcaa
    20521 atctgggcta tgagttgtcg atcacagacg aggcaaaaga tttcattgcg acaaaaggct
    20581 acgatatcca attcggtgcc cgtccgttga agcgtgcgat ccagaagtat ctggaagatg
    20641 agatggcgga gatgattatc cgtgcctcag taggtgaagg cgatacgatt atcgtagact
    20701 ttgataagga agagcagaaa atcacgactt cgataaaaaa gaaagatgct gaataagttt
    20761 gtctatgaat atagaagccg ggcgtgagtc cggctttttt tatgttcgtc catcttattc
    20821 gtctgtcatt ttgacacgca aaaaaagcat gacctaatag aatagatcat gctcttattt
    20881 ctttttttac ttaagtacgc aggatgagac ttgaactcac acgccgtaac cggcactacc
    20941 ccctcaaagt agcgtgtcta ccaattccac cacctgcgca ttttaggaag ggtgcccaga
    21001 acaggactcg aacctgcacg atcgcaaaac cactcgcacc tgaaacgagc gcgtctacca
    21061 attccgccac ctgggcaatc aatacgagaa agagcggaag acgggactcg aacccgcgac
    21121 cctaaccttg gcaaggttat gctctaccaa ctgagctact tccgcatatg caaccgcttt
    21181 gttctcgatt gcgagtgcaa aggtagtgat ttcattgaaa ccaccaagcc tttgcgctac
    21241 ttttttatta gatttttttg accaattccc taaatagttg tgtcataaca gatgctgctt
    21301 tattagccgc tacgataaca tcggcaccat catttacaaa gtcgtcagcg aagtgataac
    21361 cttcgttcgt gatgacagac ataccgaata cacgcaagcc cgcatgacgt gccacgatta
    21421 cttccggtac cgtactcatg ccgatcgcat ctcccccgac ttttccatag aaagcgtact
    21481 cggaaggagt ctcgaaggaa gggcctgtca aacctacata tacacctttc tttaacggga
    21541 tagatcggga ggcggctatt tcttccacat agcggataaa ttcacgatca taagcacgtg
    21601 tcatatccgg gaaacgagtg ccgaaatcct cattgttcgg accgatcaat gggttcggca
    21661 tcatattgat atgatcccgg atgatcatca gatcacctac cttgaacgta ttattgatac
    21721 ctccggcggc gttcgagacc aaaaggttct tgattcctaa gagtttcatc acacgtacgg
    21781 ggaaagtcac ctgttgcatc gtgtaaccct catagtaatg aaaacggcct tgcatagcca
    21841 agacttgctt atcccctagt ttgccacaaa taaaattccc cttatgcccg gtagcggtag
    21901 atttcataaa atgtgggatc tccacataag gtatcactat agggtctatt atttgatcgg
    21961 caaaagagcc taagccacta ccaaggataa tggcggtctc cgggttacct tcgatccggc
    22021 tagctaaata ggcggccgct tcccgatatt gttcggtttt aatcatttcc atatttaatc
    22081 aatttaacgt ttcatcaagt tataagctat ctctgccgct ttctccataa tctcgtcctc
    22141 tcccggtacc ttcttattct ccatcaatat tttaccatca cagataacgg tatccacgca
    22201 actgccgttg gcggcgtata caagatttga gacgaaattg aagtttgggg taaaagcggg
    22261 ggtgttgaga tctatcaaac atagatcggc taaataccct tccttgatct gcccggcttt
    22321 taaaccgaac ataacggctc cttccgcagt agcggcttgc agcatctcat ttgcggtcaa
    22381 ggcttcggga tcctttcgcc aagcttttcc taacagggaa gccagcttca tcgcctcgat
    22441 catatccaag ttattggaag aggaacaacc gtccgttccc aatcccacgg taatacccaa
    22501 ttggcgcatt tccttgaact taaaatgcat gccggaagcc agtttcatgt ttgaggccgg
    22561 gttatgtacg actttcacct cgtgatcggc caacatacga agctcgtcat catcgatgta
    22621 aattccatga gcgatgatca aacgtggaga aagcacacct aactcatata aataacgtac
    22681 gggagtgagt ccgaatctat cgagagagtc tttcacttcc ccctctgtct ctgccagatg
    22741 cagatggata gggatttggt gttccatggc gaactgatgc gcccatttca gaagctcacc
    22801 ggaaacggta tagatagcgt gtggcccgat cgagaagcga acccgtttgc tgtagttatc
    22861 cacatcttgg atcagtcgtt cgttatggcg tttgcatttc tccgcctctt ctttatcaaa
    22921 accatcgaag caaacgccgg ctatgatacc tcgcaatccc atctcttccg tcacatcggc
    22981 cgtgacacga gggcgttgat acatgtcgaa gaaagtggtc gtgccacttt ttatcatttc
    23041 caaacacgct aatttcgctc cccaatatac atcctcacgg gtcattttcg cctcattcgg
    23101 ccagatcttt tgctcaagcc acggcataag cggcatatca tcgccaaagc cgcggaacaa
    23161 agtcatggca gcatgcgtat gagcgttcac gaaaccggga atgacggctt tacggctacc
    23221 atccagtatc ttatcggcag gaaaggacag ccccgctcct atttgcttga tctcttttcc
    23281 ttcgatatag atatcaatcg ttttatcgtt aaacaggaca ttctttatta atatactcat
    23341 cttcttcctt cttatttata taaacggtag aattccgcta ccgactcgat tcccttgaag
    23401 aagatatcca actcctgact ctcgttgggc gaatggatcg cgttttgctc caagccgaat
    23461 cccatcagta cggtcttgat acctaatacc tgctcaaatg tagagataat aggaatgcta
    23521 cctccgcgac gaaccgccaa cggcttcttc ccaaatgcga tgccaacagc cttttctgcc
    23581 gcttgataag ccggcaagtc gatcggacaa acatatcctt gcccgccatg gctgggcgta
    23641 actttcactt tcacataagg tggagtcaca cgagttatat actcctcaaa catttgggag
    23701 atcttggcat gatcttggtg tggaaccaaa cgagtggaaa ccttggcata agcctttgaa
    23761 ggcaataccg ttttgcttcc ttcccccgta tatccgcccc aaataccaca gatatcgaaa
    23821 gaaggccgac aactattacg ttctagcgta gaatagcctt tctctccgaa aagagagtct
    23881 accccgatcg ctttcttata tttttcctcg tcgaatggga tttgggcgat catctcccgt
    23941 tccgcggaag atacatcctc cacgtcgtca taaaaacccg ggatcgtgat gcgtccatcc
    24001 acgtcggtga tatctgccat caatttgcaa agtacattga tcggattcgc tacggctccg
    24061 ccaaaatgac cggaatgcaa atcgcggttc ggtccggtta cttctatttc ccagtaagcc
    24121 aaaccacgta agcctgtcgt gagcgacggt gtttcagcgc tgaccatgct tgtatcggaa
    24181 acgaggatta catccgcttt caataattct ttatgttccc ggcaaaaatc ttccaagcta
    24241 ggagaaccta tctcctcctc tccttcgaaa ataaacttca cgttacactg taacaaacct
    24301 tctttaatcg ctgtctcaaa accttttact tgaatcatgc cctgtccctt atcatcatct
    24361 gctccacggg cccaaatgcg tccgtcccgg atcaccggct cgaaaggttc actcttccac
    24421 agttctagtg gttcggcagg cattacatcg taatgagcgt aaaccaatac ggtcggagca
    24481 ttgggagata ccattttctc ggcgtatacg acaggattgc ctttcgtagg cattacctcg
    24541 gccttatctg caccggaaga cagcagcacc tctgtccaac gttgggcaca tgtcaacatg
    24601 tccggcttat tctcatgctt ggcgctgatt gacggaatgc ggattaaaga gaacaattct
    24661 tcaagaaaac gatccttatt ggattcgata taagatttta ctgacatagc gttttatttt
    24721 atgtttataa attgtagcaa atataacgaa acagatgggg attgcaagaa gttttatggt
    24781 attttagccg tgttactgca ataggcgtgc agtaacacgg caaggcggat tgcagtatac
    24841 gagagagttt catcccatga tccatttagc tcgttcacct aatatacggt acatgaacca
    24901 agtaaacgcc catgagatta tgaaaatcaa aagtgccatt atgggtactt gcaaaggtat
    24961 cggtaaatca aacttcccga tcaagataaa gatcggacct acgacaaagt aatgtacgat
    25021 atagattccg aaaccatatt tggatatttt cgatagtttt ttagctatga gagtattatg
    25081 aatacgtacc ttttgaagaa gaataaatac agccgccgtc attaagacta cattcggact
    25141 acagaaggtg aaaaataact ccatatccaa ttctgttgcc ttgggattcg ctgcggccga
    25201 actgaatcca ctataggtta tggcataacc aaccacaaac atggctgcgc aaatagcgaa
    25261 ggttttccaa atattccaat tattaccttg ttttaagtaa tgtcctaata ggagatatcc
    25321 gttgaatcct gcgaaataat aaaacatgcc gaattgattc cacgtcgctt ccccgtataa
    25381 atatttgctg atataggcag acatataagg caagaaaaga gatacgaacc atatccctaa
    25441 atagaccctc tctttggaac gatccgcctt ctcgatccat gcggagaaga atggcatata
    25501 cagatacaat ccgatgagta aataaatgta ccacatatgg ttttccttaa aactgaaatt
    25561 gaacgggatc atggcgatgt ctttcaatgc gtcggataag gattgtgact catttccttg
    25621 cacatagcag aaaaactcac cgattatctc tttcggcaaa cctaatagcc ctgtaaccca
    25681 agggaatata ttgtataata cagaccatat caaaaaagga aataataccc tatatattct
    25741 ctttttatag aaaacaccta aagattgttc ccgtataggc aatagtaaaa gtcccgtcat
    25801 cataacgaaa agaggaacag agggccgtaa aagagagccg taaacagcgg cccaatgttt
    25861 atattccggt aaacttccga gtgtaggtga gatataaaaa ggatctatac aatgtactcc
    25921 gataaccatc agcatagcta cggttcgtat tacatcgagc cacacgatat gtgactgtgt
    25981 tgttgcgttg ttcatggatt tatgtgttaa atttaaaaga tgggtgacaa agatagagct
    26041 tagtatgaga attttgttta tctttattgt taatttattg tatcaagtat tatggtcaaa
    26101 cgaattatca ttattggcgc tacctccggt atcggctatg aggttgctaa gatttattgg
    26161 aaacgaggat atcaactggg attggctggc cgtcgggttg atcggttgga ggagtttcgt
    26221 aagcaagatc cggagcatat ccggataaag cagttggacg tgaccgccga ggatgccgct
    26281 gatcgtttag acgaattaat ccgtgattta ggaggaatgg acatcttcct gcttagttca
    26341 gggatcggca accagaataa atacttagat acttccattg aacaagctac gatacagacg
    26401 aatgtgacgg gttttacacg tatggtacta gctgcttatc gttatttttc cagtcaaggt
    26461 ggtgggcata tatctgtaat cagctctatt gccggaacca aaggattagg tgtcgctccc
    26521 tcctactcgg ctaccaaacg ataccaaaat atttatatag acgctttagc ccaactttcc
    26581 cgtatggaga aacagcctat tacatttacg gatatccgtc cgggatttgt ccgtacggat
    26641 ttattgaaag acggcaggaa ttatcctatg ctgatgtctc cccaatacgc cgccttgcgt
    26701 atcgctaacg ctatagaccg gaaaaagaga agggcgatca tcgattggag atacgctatc
    26761 cttgtctttt tctggagact gatccctgaa tggctttggg aatggctgcc aatacggaat
    26821 taggatcggg tatgttagag atttatcttt tttgcttcta cattagattt tctcttgcgc
    26881 cgggagcatg ctgaaggact gcgccgacta tctggcaact atctaattca tcacaatcgc
    26941 cacatgtatt aaagcctttt ccggatacac atttgcgtat ttcacaataa tcactgcaat
    27001 acgcaaattt cactccgtcc gcacgacacc ccatacagtt tatagttgcg gctgtaattt
    27061 cgggcgcatt gttcatggcg ctccactttt gggcggtttt ttctcttagc tcatcatcat
    27121 tcttaactgt ggctatgcgg gcatcgcaac tttcgcaatc taatccgcaa caggctatca
    27181 attgtttcat tatttagttg tcagtttatt ttcttgtttg tttctgtcct tgcttttact
    27241 tttcggcaaa cataataaaa attcctacct ttgcgcccaa ttactaattt tttaatctat
    27301 acagatgggt ttatttatta agaagccttt agcggatttg atgaccgagg caaatgattc
    27361 gggcagtaaa tcgctgaagc gtatccttgg cccgtggagt ttgatcgcct taggtgtcgg
    27421 tgttattatc ggtgccggat tgttctccat tacgggtgcg gtggccgccg ggtatacggg
    27481 gcctgccatt actttatctt tcgctatcgc cgccttgggc tgttgtttcg ccgggttatg
    27541 ttacgccgag ttcgcatcca tgatcccggt ggcaggtagc gcatatacct actcgtatgc
    27601 cacgatgggt gagttggtcg cttggattat cggttgggat ttggtgctcg agtactgcgt
    27661 ggccgctacg accgttagca taagttggag tcggtatttg gtcgtttttc tggaaggatt
    27721 cggagtacat ttaccgcaag ccttgacagc ttgcccttgg gatggcggta tcgtgaatat
    27781 cccggctttc gtgatcgtgg tgttaatgag tatcttgttg atacgaggaa cggaaggcag
    27841 ttctatcttt aatgggatca tcgtattctt gaaagtctcc gtagtcttgg tgttcgtagt
    27901 cttgggatgg aaatatatcc gtatggagaa ttatacgcct tatatcccca ctaatacagg
    27961 gactctaggc gagttcggat tttccggtat cctacgaggg gcggctatcg tattctttgc
    28021 tttcctcggt ttcgacgctg taagtacggc agcgcaggaa accaagaacc cgaaacggga
    28081 tatgccgatc gggatcttga tgtcattggt ggtttgtact atattatata tgctgtttgc
    28141 ccacgtgatg accggagtcg tacattactc cgcttttgct ggccagaatg gaatcgctcc
    28201 tgtggcaata gctatcgatc atatgggaca aatggatgct tctggtgtga ttcgtccgga
    28261 ttacccttgg atgaatcggg cgatcgtaat agctatttta ctggggtatt gctcggttat
    28321 catggtaacg ttattaggac agagccgtgt attcttgagt atgagccggg atgggctgct
    28381 ccctccccta ttttcccata tccatgagaa attccgcacg ccggcacgaa gtaatttcct
    28441 gtttatgtta ttggtcggta cattggctgc tttcgttccg gcgagcgtag cgggcgagat
    28501 gtgtagtatc gggactttgt tcgcttttac gctagtttgc gccggggtat tgattgtccg
    28561 taagacaatg ccggacgctc cccggtcttt caagaccccg ttggttccgt tcgtgcctat
    28621 cgccggtatc ataacttgtc tggtgatgat gctttttctc ccggctgata catggattcg
    28681 tttggtatta tggatgttaa tcggtctgga tatatatgtc tgctatggaa tcaaacatag
    28741 caaactggaa catatgcaga aacatcgctc gggacagacc acattggata tgatcggtat
    28801 taccctatcc gtgctttgcg tgattacggg gctttggcac cagcaaaccg tgggatgggg
    28861 cgagagcaaa gtcttattga ttatctcatt cgtattcgct tttacgcatc tagctttcta
    28921 tctttacaga ctcgggaagc agtttacgag ccttacccgt tagcgattca gcacgattat
    28981 gtctcgatgg ctcacgcgac tagtcccgat ggtcaacgcc attagtggtg aaggcttatg
    29041 cgagtagtcg cgttgacctt caccactaat ggcgtactat accacttcct ttgatacgat
    29101 ttatcggatt ctagctctta aaagtaagcc tcttattcat cataaaatta acggctccgt
    29161 aaacgaaaag tccaaggaac tgacccaaat attcatttag atcgatcacc tccaccatta
    29221 aaagcaagaa tatgaattga gtagcgtaag cgcaaccaaa agcgattagg aataaaggaa
    29281 tctccttcca gaaattacct ttcccggaag aaaataccca gtatttactc caaaagaagt
    29341 tattcaccaa ggcagccaca tatccagcca tgttcgacca caagtaatta caatccagaa
    29401 tatccattaa tatccagatt accaatgcgg tgatcaaagc gttagaagaa cctacaatgg
    29461 cgaaacgaag aatacgaaca gattccttca tgctgttaat tatacgtttc gaatgacaaa
    29521 tatacgggtt tatttctata tttgtgctgt acttttgatc aagtatgtaa cattcttaaa
    29581 acaattatga gtatgattag actaaatgta tttattcaag taagtgagga gaatcgtccc
    29641 gccgcattgg agactgcgaa agaattggtt gaaaagtctt tgaaagacaa tggctgtatt
    29701 gcttatgata ttttcgagag cgctacccgt agtgatgtat tgatgatttg tgagacgtgg
    29761 aaagacgctg aatccttatc aggtcacgaa aaagcggagc atttcgtaac gttggttcct
    29821 aaattgcaag gattaggtgc gatgaaactt gagaaattta cattttaagg gttttatgta
    29881 ggatcttatt ataagcctga gcatgctaaa aaatcatagt tatgaatcct tcaacttata
    29941 actatgaatg aaagaaaaca taactatgat ttttttagtg ttatcgctcg ttgattgaga
    30001 tatattccct atcgtccaaa acgttcttgt aagccggacg gatgatgcgt tttccgtcaa
    30061 agttcaactc ctcgatacgg tgagcggtcc aacccacgat tcgggccatg gcgaataaag
    30121 gcgtatagat ttcctgtggc aaaccgatca tctcataaac gaatccggaa tagaagtcca
    30181 cgttcgagga aacccgtttc ttggttcctt tatgcttggc gaaacattcg atcgccctct
    30241 cctctaataa ctcaaggaag gcgaattcct cggagcgacc tttctctttt gccagatcac
    30301 gagccagttc ctttaatacg accgcacggg gatcggaaat cgtatagacc gcatggccga
    30361 tgccatagat caagcccgtc ttgttataag cctctttgtt cagcatccgc atgaaataag
    30421 tatcgatctc atccacgttc ttccaatccg cgatattctc tttcaaatga tggaacatat
    30481 ctactacctg aatattggca cctccgtgca acgggccttt caatgagccg ataccggccg
    30541 cgatagatga gtacgtatcc gttcccgtag aactagtgac gcgtaccgtg aacgtggagt
    30601 tattaccacc gccatgttcc gcttgcaata ccaagagcaa atccaacgta cgtgcgtcca
    30661 gatccgtgaa atcacgtttc agcatgtgaa ggaagttttc cgcgatcgat aagttctcgt
    30721 gcggatgacg gatatgtaaa gaacgcccct gtgtgctatg acgataaata ttgtacgcat
    30781 aagcgataat cgtcgggaac ttagagatca attcaataga ttggcgcatt aagttatctc
    30841 gggaggtgtc gtccgggttt gcgtcgaagg tatacatttc caatacgcta cgagccagta
    30901 tattcatgat gttctgtcct tccagatcca gaatattcat cttggtcttt tgctccaagg
    30961 gcatattatc gttcaacagt tctttgaagg ctgataattc ctctttatcg gggagtttac
    31021 cggagagtaa taaataagcc acttcctcga agccgaaccg tttttccttg atgaaatcac
    31081 gtgctaaatc ctctacgtcg taacctctat agaataactt accggggatc gctttaagac
    31141 cgccctctgg caagcgttcg tatcctacta cattaccgac ttgggtcaat cctactaaca
    31201 cgccgctacc atcctcgtta cgaaggccac gtttcacatt atacatcggg aaaagttcgt
    31261 tgtcaatctt gcaagcctct ctggcagcct cggacaattt gtaaattaaa tattctttct
    31321 tcaacatgac tatactaatt taattgtttc gataatagag atgatacgat caccaaattc
    31381 tttggtgccg agagatttgc cgttcggcat aaaacgagcc aagtcatgag tggcctctcc
    31441 agcggagaaa gcttgctcca tagcagatgt aatcaggtta gccgcatcac tccatcccat
    31501 atattccagc atcatcacgg atgataataa taaggaagag gggtttacga gattctttcc
    31561 cgcgatattc ggagcggttc catgtgttgc ctcgaagatc gcatgaccac tgttatagtt
    31621 gatattagcg ccgggagcaa tgccaatgcc acctaccatc gccgctaatt gatcggagat
    31681 ataatcgccg ttcaggttca aggtagcgat cacggaatat tcttccggaa ttaatagagt
    31741 gttttgcaag aaagcatcgg ctatgacatc cttgataatg attttaccgg cctttgaagc
    31801 ttccactaag gcggtattgg ccgcttcctc gccttgctct ttcttgatct tctcatattg
    31861 aggccatgtg aaagtgagat ccgcaaactc ccgttccgct aaagcgtatc cccatagttt
    31921 gaaaccacct tccgtgaatt tcatgatgtt acctttgtgt accaaagtca cgctcggtaa
    31981 ctgatgcaat atcgcgtatt cgatagcggc acgcaccaga cgctccgtac cttccacaga
    32041 aaccggcttg atgccgaaag aggaagtttc cgggaaacgt attttcttca ctcccatttc
    32101 ctcggtgagg aacttcaata acttttgtgc ctccggagtc ccttgttgcc attcgattcc
    32161 ggcatagata tcttccgtat tctcacggaa gatatacata ttcacttttt gcggctcctt
    32221 taccggagat acgactcctt taaaccaacg taccggacgg agacaaacat ataaatccaa
    32281 cgtctgacgg agggccacat ttaatgaacg gatacctcca ccaatcggag ttgtcaacgg
    32341 tcccttaata ccgacgatgt attcacggaa tgcttccata gtctcatcgg gaagccaact
    32401 tccggtttgc ttaaacgcct tttcaccggc taagacctct ttccattcaa tggaacgggt
    32461 tccgttgtaa gcttgcttga tggcagcgtt tactatcttt tggctaacgg gagtgatctc
    32521 atgccccacg ccatctcctt caatataagg gatcgtcacg tgatccggaa cgaaaatatg
    32581 attacctttc tttgttatct tactcatgat atcaagattt ttttgtttgt cttagtgagc
    32641 tgtatttaaa gcggaacccg ccttgaacca tttaatttgt aaatcattat acgtatggtt
    32701 aaccgggaat gattcttgcg taccatccgc atgaagaaga acggccgtca acggtttgcc
    32761 cggctgaaaa tctttcaatc cgatgatcga gatatggtca ttctcgcgga tcttgctgta
    32821 atcctcctta ttggcaaaag tcagtgctaa cattccttgt ttcttcaagt ttgtctcgtg
    32881 gatacgggcg aaactcttgg ctaggatcac ttttacattt aggaagcggg gctccatggc
    32941 tgcatgttcc cgggaagagc cttcaccgta gttttcttcc gctacgacga tcgaggaaat
    33001 actatttgcc ttgtattgtt tcgctacggc agaaactgct tcatattcat tgttcagttg
    33061 attcaataca gagtttgtct tcccgttgaa agcgtttacg gctcccatca acatattatc
    33121 cgatatattt tccaaatgcc cacggaaacg taaccatgga ccggccatcg agatatgatc
    33181 cgtcgtacat ttaccttcag ccttgataag aaggggcata tccgtgaaat cctctccatt
    33241 ccaaggagcg aaaggcttta atgcttgtag gcggttggat tccggatcga tgttcaccac
    33301 tacgttctta cccgtaggtg ccagatagcc gttatccttt acctcgaaac ctttcggcgg
    33361 aaaatccgag cctttcggtt ctttcagttt cacaacctta ccatcctctg tcttcaaggt
    33421 atcggtcaaa ggattgaaac atagatcacc tgcgatggtc aaggccagtg tcagttccgg
    33481 agaagcgaca aaagcatgtg tattcggatt accgtccgca cgtttagcga agttacgatt
    33541 gaatgaagta acgatcgaat tcttacgggt attatcatcc gtatgacgtt tccattgtcc
    33601 gatacaagga ccacaggcat tcgccataat ggttgcgcca atccgttcaa aatcaccgat
    33661 aataccatct ctttctgccg tataacggat ttgctcggaa cccgggttga tgatcaaggg
    33721 tgccgctacc ggtattttat cctcataagc ttggcgagca atagatgccg cacggcttag
    33781 atcttgataa gaagagttgg tacaggaacc gattaatccg acctccatct ttcggggata
    33841 gccattcgct tttacttttg cggcaaactc cgagataggc gtagctgcat ccggcgtgaa
    33901 cggaccgttg atatgcggct ccaattcgga aaggttaata acgattacac gatcgtaaaa
    33961 cttatctggc tcggcacgaa cgtccatatc cgcttccaga tattcaccga tagcttcggc
    34021 ccagctcgct acctcgtcac gtcccgtggc acgaagatat tgagccattg tattatcgaa
    34081 tgggaataag gaagtagtcg ctcctacctc ggcacccata ttacagatcg tagcttttcc
    34141 ggtcgctgag attgaggcgg tgcccggacc gaaatattcg atgatagcgt tcgttccacc
    34201 ttttacggtt aagatgcccg ctagcttaag aatcacgtcc ttcggcgagg cccaaccatt
    34261 caaactacca gttaacttaa caccaattag tttcggcatc ttcagttccc attccattcc
    34321 ggtcatgaca tccacggcat cggctcctcc tactccgata gcgaccattc caagtcctcc
    34381 ggcattcggg gtatgtgaat cagttcctac catcataccg ccgggaaacg cataattttc
    34441 caataccact tgatggataa tgcctgctcc gggtttccaa aaaccgattc catatttatc
    34501 ggagaccgat ttcaagaaat catagacctc gctattgctt ttggtagccg tatcgatatc
    34561 cgttttggct cccatattcg cttggatcaa atggtcgcaa tgcacggtag ccggtactgc
    34621 ggatttttct tttccggcgt tcatgaattg taaaagcgcc atctgagcgg tggcatcttg
    34681 catagccaca cggtcgggac ggaaattcac ataatcctca cctcttttga aaaggcgagt
    34741 cgagctttca tcgtatagat gcgcatataa gattttctcg gccaaggtca tcgggcgacc
    34801 accgatacgt tcgcgggctg tgtccactct tctggggaaa ttcacataga aatttctaag
    34861 catgtcaatg tcgtacacca tattcatatt cgttttttat tgtaagcctt ttcgcaaata
    34921 tatttatcta taaccagcta aaatgtaata aataagacat ctgccaatga gtctttgttt
    34981 ttattatcaa caaatatata atataatgaa atacaatttg ttcgataatt tctatgaggt
    35041 tatagaggtt atttataatc tcccggataa cttagaaaaa cgggctaatc gcacgtttat
    35101 taataaaacg taccattagc ccgttttgtt caagccttgg agctgttttt tctacttatc
    35161 gagactttct ttccatcttt gagcataact atgtaaaata gatgcgatac cctctccaat
    35221 ccggacataa tcttcccgtt taaggttggc taaagatgcg cggatagacc actcgggagc
    35281 atcaaaacct cctccgttca gtaaaaccaa ggaagtttcc tgtgccagac ggaaaacgac
    35341 atccagaggt tcgtaattct tttttagata ttccacgaaa tcatccccat agaatttctt
    35401 agcccagaca agcatatcga tctcactata gtatcccgca cgcaaagggt cgtccaataa
    35461 ggtgaatccg gtgctttccc acaatgtgtg taaacgctcg tggatcatat cctgcatcct
    35521 tttcttatag gtattttccg catctaatag agcgaaagac gcaaacagag acatttgtgt
    35581 ttgttgtggc aaggaaagac cggccgtatg attcaaggct acttgacggc tatcggctac
    35641 catacgatca ataaagcgga tatcctcggg atgtaaggat agactgctat accgtttttt
    35701 tagaagctcc tgtttatctc ttggcaattc acggatcatc cggtcgtaaa tattatcttg
    35761 atgtaaagcg attaccgcca atctccatcc ggttgccccg aaatatttgg agaaagaata
    35821 gacacataac gtattctttg gtaattcggc catcatcgag cgaaaatgcg gaataaatgt
    35881 cgcatacaca tcatccgtaa taatcataag gttgggattg tcgttccgta cgatctcaac
    35941 gatcctattc atcaatgctt ttgtcaatcc gtatgaaggc gggttgctcg ggtttgttat
    36001 gaaagcggct ttcacgctag gatctttcag gacatctaaa tccttttctt gatattgcca
    36061 cgtgtgatag ccgtcttttg tcatcttcaa ggcttttatc tctatgacat taaaaagata
    36121 acgagcctgt tccggaatct ctatataagg agtgaatacc ggagcgaaga gaatgatctt
    36181 gtctccctta ttcaacaaga aattctgctg caaggaatcg aagatataac acatggcggc
    36241 agttccgccc tcggtagcga aaaggtcgaa tattccctca gggggctggt tatcacataa
    36301 ttcttggtct aaataatccc gcacgagcat ttccgtatat ttcaagatac gatcgggaac
    36361 cggatattga tcaccaatga caccttccgc ccattcgtat acaagctcat tctcatctac
    36421 acctttttcc gtgaccagat attcataggt acccttcaat aaagtagcgc cgggagattg
    36481 cgcatgtttc tttagaaact gtacgaagcg agacgcgatc cttttgcggt tgggaacccc
    36541 tgcggctccg gccatctcat ctgccaattc ggtttcccgc tggcattcct ccaaggcgaa
    36601 ctgccctaat aggaagaatg cctcccgtgg aaccgtactg atccagtttg gatttcccct
    36661 tcctgcgttc agcatgatgt gcgtactttt acgagcgctc tcatccgcta actctatcaa
    36721 gatgttcttt agctcgaaag ggctaatctc cgacatcttt ttctcatatt ctctcgtgac
    36781 atgtattttc ttcttgtcca tacattatat atattacatg attagcacaa taacgacacc
    36841 ccagatgatt aataaagtat tacccaccgc ataggtaacg gtatagccta aggctggagt
    36901 ctcacttcct acggcatctt ccaccgctcc taatgcggcg gttgtcgtac gtgaacctgc
    36961 cgtgcaacct aaagtgatag ccggatggaa cttaaaaacg taacgtccca tcagaatacc
    37021 gatgataagc gggatagatg tcgctaaagc accgataata aataaactta taccgacttc
    37081 cttcaatccg gtcacgaaac tgggacccgc cgtgataccg actacggcga taaacatatt
    37141 cagtcccaaa ttatttaata tccagacgga aggctccgga atacgcccga aggtcggatg
    37201 cttggaacga agccatccaa agacgagtcc ggctatcaaa gcgccgccac tcgtactcag
    37261 gctgatcggg acacctccga aatgaatcgc gagcgaacct aaaattcccc ctaagaaaat
    37321 accgataccc acgaaaatca aatcggtctg attggttggg cgatcgggat atcctaaagt
    37381 cgtagccgct ttatttacct ctgatttcat acccaccaat tccaacatat caccggaatc
    37441 tatcaccgta gcggccaaga ccgggatatt gatacccgca cgccttatgg acttgacgct
    37501 aacaccgtgc atgaacgatt gattgcgtaa atagcagatc tttttcccca cgtattcctt
    37561 atggatcact agtacgggta acgtctctgc cggaaaatcg agcaattcaa tgtcattgac
    37621 ctcgtcgcca atccagttct cctctccgat cacgaattcc cggcgaccgc ttaggacaac
    37681 ctcatttccg gtatgtaaaa ccaaatccgg tttaacatcg gttagtacat tattaatacg
    37741 gacacgctcc acgaacaaat gccgtcctaa ttggtccaga tattcctcca actgctttac
    37801 gcttttaccc tccttgaacc attcattact aatcttatag gcccggaaag ttaccggacg
    37861 ggcggcaggc ataaagcccg gttgctcgct ctcgtcgtta tttcccattt tagcctctag
    37921 ctctttacag gcttttttca cgtagtcgag tcctcctaaa agacgtggcc cgatatcact
    37981 caccaaccat gcggatcctg ccgtaccgaa aatataagtt accgcatagg ccacgggcat
    38041 cacgttgacc atagcgcttt tatccgtatc gctaatattc atctgtccga tcgtatcttc
    38101 ggcaactcct aatactgccg acatcgtctg ggagcccgcc aataatcctg cggcctcgcc
    38161 tgcgttatat cccataagtt tcgccagtaa aaaaggagcg atcaagcaaa acacacacat
    38221 gacggcggcg aaaagcattt gaggaagacc ttcctttttc aatccccgga agaactgtgg
    38281 cccaacacta tatcctacag cgaagaggaa catcaagaaa aagacggact ttaacggtcc
    38341 gcttatatcg atttttaatt gcccgatcaa tacaccgacc aataatacgc tggtaaccgt
    38401 tcccagcgtg aacttcttta tcttaaactt gccaatccag aaaccgagag ctaaggttat
    38461 gaaaatagct agctccggat aatgttgaag taaattagtt atccattcca tatctattta
    38521 tttgatgtta aacaaaaaag atgctattgg aacagggatt ctttgaaaga tgttgttact
    38581 tttcgggatt atttatataa atttgcgacc gcttaggtga tagagtttgt ctaccgacaa
    38641 ctctataaaa gggaatccgg ttagaatccg gaacagtgcc cgctactgtg aagctcttga
    38701 aaaggaaagc gttctgctat gccactgtct taagaaagat gggaaggttg ctttccgagc
    38761 caatcaggaa acctgccaag cgaagtaatg attaattcct cccggggtca ggagtaatta
    38821 agaggataga aatatcacct atatctaaaa gatgttggag acgtaataat acgttgtctc
    38881 cgtgggattg atatgtaatc taattattaa tatattcata tgatgaggaa acacttacta
    38941 tctttcttct tgctggtcat cagcctagtt tgtcgtgcgc acgatggcga gaattttgta
    39001 gcatccgatt tattcgcctc tttacaaccg ggcgataagg ccgctttatt gatggtacat
    39061 tttggaacaa cccatgatga tacccgtgcc ttgacaatcg acgcgatcaa tcaaaaagcg
    39121 aaagaagctt tcaaagatgt tgagttgcgt gaggcatgga cttctcgcat tgtaatgcgc
    39181 cgcttaaaag ctcgtggcgt agagaaactg aacccgatcg aggccttgga aaaattaaag
    39241 actgatggtt atacacatgt cttgatccaa tccacgaata taatcgaagg tatcgagatg
    39301 gaatccttac gtaaggatgt tgccaccatg aaatcttctt tcaaggagat tcgtatcggt
    39361 aatcctttat tgtatacacc ggaggattat gaggcggtaa tcgtcgctat cacaaaaaat
    39421 ggggcgaaag aaggcgctac tttattggta ggccatggca cttatactcc ggcgacggct
    39481 caatatgcca tgttggatta tatgttgaag gagaagggat tcaaggatta ttccgtagga
    39541 accatcgagg gctatcctac ttttgatacg atggtagccc aagtaaaggc caatggaacg
    39601 aagaaagtct tgttgatgcc atttatgttt gtcgccggag accatgcgaa aaacgatatc
    39661 gccggtgatt ggaaagagga actggaaaag aaaggctacg aggtaagcgt atttatggaa
    39721 ggtctgggac agaatccgga tattcagaag atcttcatcg aacatgcccg tttcatggct
    39781 aaacataaga tgatcgatat cgttgataag aagaaagctt atgcggtaga gaaggactaa
    39841 aaaagttctc caaatctatg ttttattcct ttcggaagaa aaagtaattc cttccgaaag
    39901 aaactaaatt ttcattcgaa ggaaaatgga atttctttcg aaagggattt cacatgcata
    39961 caataaacag ttataatgct aaatatatga aaagagtttt gacaatctta ccgttgacag
    40021 ccttatgtat cagtacgatg caggcacaac acaagaatga gtacacgaat ttcgccgata
    40081 cgacattcaa tattcaagaa gtcgtagcga ccgccgcacg caagccacgt ccacaaatca
    40141 cgaagttgga cgtacctatg aaatatcttc ctatttcaat taatagcatt acggcgagta
    40201 gtttggagtt gcgaggtatc cgtaatatcc aagatgcggt acgctttatg ccgggcgtac
    40261 gattccagac atcttatggc gcatttcaac aattgtcgat ccgtggtttc gatcattcta
    40321 tcatgatgat agacggtatc cgcgatgaac gttcggcaat aaacaactct tatcccgtac
    40381 ccgatctatc ctgtatcgag tctattgaat tattaaaggg accggcttct gtactttacg
    40441 gacattcagc cgtaggtgga accttgaata tcgttcgtaa atccccgtca gagaaacaga
    40501 gcgttaatgc tcgattggcc tacggtagtt acgagaataa agaggcgaca cttggcatgg
    40561 gcggtaaatt ggtcggtccg gtcaattatt acgccaatgt caacttttcc gatcaagagg
    40621 gctggcgtga taatggcaac cgtcgctttt ccggttatct ggcattgcaa gctaaaatga
    40681 cggaacgtga catattagat gttcgcggag gttttaaccg cgacttctat gggacggaga
    40741 tcggtcttcc cgatttaatg gcaaatgatg tatataatgt gcaaacagga cagttatatc
    40801 tccataaaaa tgagatgcta ccgggacttg accgtgaggc tcgctacaat aacgagtccg
    40861 actttatgaa gaatcacgca tggaacgtat cgacgcaata cacacatact ttttggaacg
    40921 gcgcgaaact aacagatcgc ctttcttaca ataacgacga tatcaactat tttgggacgg
    40981 aagccctcga ctatctcgaa agtgatgatc cgatctatga tcattattat atgaaaaacg
    41041 gccagaaaaa atatatctgt ttggacagtg tatatctttc tttcccgctt cgcttctccc
    41101 atatagccaa gacggtagcc aatacgctcg agctaagcgg taaattcagg acgggtgaga
    41161 taaagcatac gtatatggga ggttactctt tcgtcgcctt gaatcgtacc agctattcgg
    41221 gctataattt aggagatgat gttcagggtc ccggccttta ttcgcatgta tccgtttatg
    41281 atccgcatag catgggatat atgaccagta aattctcgaa agcaacggtt acgcatcatt
    41341 attccaacag cctttatctt caagatatgg ttgagttcaa cgagcaatgg aaggtattag
    41401 ccgctctacg ttacgacttt ttccgttata tgtccgccag cgctacaact cctaccggac
    41461 gacgtgagta tgaggagcat tcaagcttca atatgataaa gaataaggcg ttgacttatc
    41521 gtttcggagc ggtctatctg ccccatccga atacatccat ttatgcgtct ttcgcctctt
    41581 tcttcaagcc gatccgtacg ttctatcaag ataacgtcat ttatgtagga ggtgatggaa
    41641 atcgtttcga gcctgctcgc aatgaggaag tatttaagcc ggagaaagga taccaagccg
    41701 aggtgggtct taaatatcaa ttgaacaata tattaagcgc caatgccagc ttgttctata
    41761 tccggaagat gaacagtacg gctacgttga ccaacaacta tcaagaggaa gtaaacggcg
    41821 agactaccac gatgagtgta atcggacagg tgggtgtaca agattccaaa ggttttgatt
    41881 ttgatgtcac tctttctccg gtaagcacct tagcgctgac gatcggttat ggattgaacg
    41941 actccaagat ccgggagatg aaagaaataa aggatccgga attgatcgag gctatctatg
    42001 gcaataaccc ggatgagaca aagcaacaat tgaatagcca agaaggaaac tggcagagca
    42061 acgtaccgaa ccagactttc tacgcatacg gcagttatac catccctcgg ggtgtcttga
    42121 agaatctgga atttcacttg agtagcagtt ataccggtaa agtataccgt aatacatcta
    42181 acaactcttg gttcgatccg tattgggtaa ccgatttcgg tatgtcttat ttgttgaaca
    42241 acaatattca ccttacattc aacttgaata acttgtttga caacaattat tataaccaag
    42301 cgctcggaca acagatggtg ccaagcatgc ctcgtaattt ccaagtggct atctcctata
    42361 cattataata tatagaacat acgctcatga atctattgac aaagatcacg ctatttatac
    42421 acaggatact gggcacggcg ttcagtatcc tgtttctcgt ttggttccta tcgggattgg
    42481 taatgatcta ccatacgttc ccgcgagcgg accgggccga taaacgggcg aagatggata
    42541 ttctctctct ggagaatctt ccttcgttag accagataga gaaacgttta ccgcagaacg
    42601 agcggataag ccatgttacc ttaaacagct atttgggaca aactgttttt catatccgga
    42661 cggagaaagg gagctatgat attcctgccg actcgacgga aagattaccc gtaatcgact
    42721 ggaatcatat ccaacgtgtg gcatcactat ggaatacctc ttccatagcg aaggtagatt
    42781 ccttgtacac cttggaccaa tggattccat tcggtcgttt aaaagaggaa tttccgatct
    42841 ataaattcca tttcgccgat ccggaacgac atgaattata catatcctct aaatccgggg
    42901 aggttttgca atatacggat aaaaacagtc gtttctgggc ttggctcggg gcgatccctc
    42961 attgggttta tttcacttcc ttgcggcaag acgctgaatt atggataaag gtagttgtct
    43021 ggttatccgg cattggatgc gttatgtgta tcgctgggat ctatttagga atacgggatt
    43081 tccggttagc gaggagacgt catttgattt ccccttataa gaagttctgg tataaatggc
    43141 atcatattct tggggtgtta ttcggtttat ttgtcctcac cttctgcttt agtggtatga
    43201 tgtctttggc tcgtgtacag gattgggggt tgaaagccaa gcttgatata aacccggttc
    43261 aagaactgcg gaagatggct ccttccccac tcgattatcc gttggattac agggcggtca
    43321 tacaagccta ttccggccag atccgtcaat tggaatggag tagttttggt gatataccct
    43381 tttacatcgt acaaacagac acgaaggata ttgtcgtgaa cgcaaataag agtgacggga
    43441 tatctttatt gaacctgcga ccggaagaaa tccgttccgt attgtctcag atacatggta
    43501 tcgggaccac ggctgatatc aaactgttgg atgcttatga tacgtattat atctcacgaa
    43561 aaaggaattt agaactcccg gtctggaaag tatctattca agacgtggat aatagttgtt
    43621 attacattaa tccccgtaat ggacaatacc gttatgtaaa tacgccgtct cgttggaacc
    43681 attggatgta tccggcattg catagcttga atctgaaatt cttggtagat catccggtct
    43741 tatggaatat cgtgatgtgg ggaaccatgt tgggaggcac gttcgtttcc ttatccggtg
    43801 tatggcttgc gataaaatat atcaggcgaa aagcgagaag aaagaagtaa agcctgtata
    43861 tttgtattat atttattgag aacattgtat tataaaatag atttgaatga ataaaggcaa
    43921 gattatagtc gccggaatcg gccccggtag cgaggccgat ataacgcctg cggttttggc
    43981 cgctatccaa agctcggatg tcatcatagg atataaatat tatttccgtt ttatcaccca
    44041 cttgcttcgt gagggaacgg aatgtataga tacaggtatg aaacgtgagc aagctcgtgc
    44101 cgagcaagct ttcgcttatg ccaacgaggg aaagacggtt tgcgtgatca gttccggtga
    44161 cgccggtatt tatggcatga ctcctctgat ttatgagatg aagaaagaat ccggaagcga
    44221 gatcgagatc gagtcgtatc cgggcatcag cgctttccag aaagctgcgt ccttgcttgg
    44281 cgctcctatc ggacatgatt tctgtgtgat ttccctctca gacttgatga ctccttggga
    44341 actgatcgag aaacggattc acgcggcggc catggccgat tttgttacgg cgatctataa
    44401 tccaaaaagc gagggacgtt attggcaact ctatcgctta aaagaattgt tcctgcaaga
    44461 acgcaagccg gagactccgg tcggttatgt acgtcaggcc ggacgggagg agcaagaagt
    44521 attcgtcact acgctcgcag atctggaccc cgagcagatc gatatgttta cggtagtctt
    44581 gatcggaaac tcacaaacat atctttccgg gaatcatatg atcactcccc ggggatatta
    44641 tggcgagatc aaacaaaaga aaatggatac gggtatcgga caggacatca tgatccgtag
    44701 tttccgtacg atcgagaagg aattgaaaaa ccaaaagatc ccgttggata agaaatgggc
    44761 gttactccat gccattcata cgacggccga tttcgatatg gaaaatatcc tttatgccga
    44821 cccgaatgct gtctctacat tatataataa gatcagcggc ggggaagttc ctacgatcat
    44881 caccgatgtc acgatggctg cttccggcat tcgtaaggga gctctgcaac gtctgggtgt
    44941 cgaagtgaaa tgctaccttc aagacgagcg ggtcgctgag atggcttcga gcaaaggaat
    45001 tacccgtacc caagccggta ttcgtcgggc cgtggaagag catccgaccg ctctgtttgt
    45061 cttcgggaac gccccgaccg cccttatgga attatgcgat ttaatacgta aaggtaaagc
    45121 cactccagct ggcattatcg cggctccggt aggtttcgta catgtgcagg aatccaaaca
    45181 tatggtgaaa ccttttatcg gtataccgaa actaatcgtg gaaggtcgta aaggaggtag
    45241 taatttagcg gctacgctag tgaatgccat cctttgtttt aatgacgcag aacaattaaa
    45301 gccgggaaga gacgtatgaa ccgattttat gtcatagggc tggatgataa tatgcggcaa
    45361 tactttccgc cggagatatt ggagataatc tcgtcccacc gggtgttctc cggaggcgtg
    45421 cggcatcatg agatcgtacg ttcgctcttg cccgagaaag cggactggat cgatataaaa
    45481 gtcccgttgg acgaggtctt cgatcgctat cgttcgtacg acggtcggga aagtatcgtt
    45541 gtattcgctt ccggagatcc tttgtttttc ggattcgccg ttacgattca aaaccgattg
    45601 ccggatgcgc aaatccgcct gtacccgtca tttaattcct tgcaactctt ggcacaaaat
    45661 ctattgatgc cttaccacga tatgcggatc gtctccctta ccggacggcc ttggcacgag
    45721 ttcgatcgtg ccttgatcga aagtgcgtct aagataggcg tgctcacgga tcgggaacat
    45781 acgcctacga ctatcgctcg ccggatgctg gaatacggct atggtaatta taccatgttt
    45841 gtgggagaac ggttaggaaa taccgaacgg cagagcatcc gccaattcag tatacaagcc
    45901 gcggcaatga ataatttcgt tcatccgaat tgcttgattc tccggaaaga gcgtgacggg
    45961 cattcccgta agttcggcct gccggattcc gctttcgagc atttgaacgg acgggagaag
    46021 atgataacca aaatgccgat ccgtttgtta tctttaagca tgctggatct gataaaccgg
    46081 gaacgttttt gggatatcgg cttttgtacg ggttctgtct cgatagaggc taaattgctg
    46141 ttcccgcatt tgcatatcac gagttttgag atccgggaag agggacgaaa gttaatgact
    46201 gagaattgtc atcgttttgg gactccgggt atcgaggcta taatcggaga tttcttatcg
    46261 gtggatttat cagcgttgga ggctccggat gcaatcttta tcggcggaca tggcgggaaa
    46321 ttagtggaga tccttatggt agtttccaaa aagatgaaag agagcggtgt catcgtcttc
    46381 aactccgtat ccgacgaaag caaagcgctt ttagaggaag cggtccgcca aaccggtctt
    46441 cggatatccg cccaaacccg tatcacgatt gatgatttta atacgattac cgtgaatgtt
    46501 atttataaat tatgagtaca atatcaatta ttccaatatc cgatagcagc cgggtgcttg
    46561 ctgagcgaat tctagcctct tatcccgagg cgaagatctt accattcggc tctttctcaa
    46621 aagaggtttt tcacgaatcc agtagtttgg tatttatagg agcgatggga atttgcgtac
    46681 gcagtatcgc tcccttcgcg gaagataaac ataccgatcc ggccgtggtt tgtatagata
    46741 gtaccggcaa atacgtgatt cctgtcttat ccggacatat cggtggagcg aacgatcttt
    46801 ccaaagagtt agcgaaccta ttaggagccg aagcgattat tacgacacaa agcgacaacg
    46861 caaacctatg ggcgctcgat acattaggga agaaatacga ttggaccttg atcgccaaag
    46921 atagcaatgc cgccatctcc acttttgtca atggaaaacc gacagcgcta ctccttgata
    46981 tacgagataa aggaacggat tatttggagc gtacggtccc gtctcatgtc tctatctttt
    47041 attccttcga ggcgataccg cagcaagact atgagttatt gatgatcgtc agtccccaac
    47101 aatacgatac atccatccct acgatcacct atataccgaa agtcctccac ctaggaatgg
    47161 gttgccgcaa ggatatgcaa ggcgatccta cggtcgttta cgaacatatt aaagatgtat
    47221 tgcgtgataa acgcctatat ccggaagctt tggcggatgt aaatacaatc gatttgaaga
    47281 aatgcgaacc ggtgctgaca ttactggctt atggagttat ggaatgccct ttccacacct
    47341 atacatcgga ggagctgaaa gatatcccgg tacccaatcc ctcggagaag gtactggagg
    47401 taaccgaatc ctcaagtgta tcggaagctt ccgccattta tgcggctcat ggcggtccgc
    47461 ttttggtcga gaagcaaaaa gcggatttag ggaaaggaaa tgaatatacc tttgccgtag
    47521 cgttagatcg gacggcctgc cgcaagggac atatcgagat cgtaggagcc ggtcccggcg
    47581 atccggactt gatctctatc cgcggacggc aaatgttgga gaaagcggat ttgatcctgt
    47641 atgcaggaag cctcgtcccg aaagaactta ccttatgcgc gaaggcaggc gctacggtgc
    47701 gaagctcggc ggatatgaat ctggaagaac agttcgcgtt gatgaaagag ttttatgata
    47761 aaggattgtt tgtcgttcgt ttgcacacgg gcgatccttg catctatgga gctattcaag
    47821 agcaaatgaa ttactttgat caatacggga tggattatca tatcactccg ggtatttcct
    47881 ctttccaagc cgccgccgcc gctctttatt cccagttcac gattccggag aaagtacaaa
    47941 cgatcatcct cactcgtggc gaaggacgta cgcccatgcc tgagaaagag caactgcaca
    48001 aactggctca aagccaaagt acgatgtgta tcttcttaag cgccggtgtc gtagagaagg
    48061 tccaagagga attattgcga cattacgctc caaccactcc ggtagccgct tgctataaat
    48121 tgacatggaa agacgagcgg atctaccgtg ggcaactgaa agatctcgcg aaaatcgtaa
    48181 aagagaatca tcttacactg acaacattac ttgtcgtcgg ggatgccatc gataatcgca
    48241 agggtctatc ccgcttatat gcggatgaat tcaaacatct tttccgtaag taatgatact
    48301 gatccttgga ggaacgacag aaggccgtgt ggctgtgcgg gtagcggacg aggcagccgc
    48361 tacctattac tattctacga aaggaacttt gcaatccatt gaatgtgcgc atggaatccg
    48421 tttgaccgga gccatgaatg cggaggaaat ggagtgtttt tgtcgtgacc acgcgattaa
    48481 gctattgatt gatgcggcac accctttcgc tcaagtgtta caccaaacga tcgaaaaagt
    48541 atcgaaatgt ttacagattc cggtgatccg ttacgaacgt cggtatccac ctcgtgatga
    48601 ggacttgatt tggtgcgata gttatgcaga cgcaattcac caaatggaaa acaaaggtat
    48661 ccaacggcta cttgccctca gtggcgtgaa cacccttgcc ccgctccgcc cttattggcg
    48721 atcgcatacc acttggttcc gtatattgga gcgggaggaa tctttgtcgt tggccgagaa
    48781 gcagggcttc ccccaagaac gtctggtttt ctatcgagaa ggtgaggatg agttaaagtt
    48841 gttggagcaa ctccatccgg atgcgatctt gacaaaggaa agtggtttct ccggctattt
    48901 tacggataaa gtgaacgctg cccgccaatt cggaatacca gtatttgtcg tgaagcgtcc
    48961 cgcattaccg gaaactttct accgagtgta tggtgaagac ggattgcgnn nnnnnnnnnn
    49021 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    49081 nnnnnnnnnn nnnnnnnnnn nnnnnnnngg cccggctata aacgccacgc cccgtaagat
    49141 gatccggcaa gagctgattc cactcctgcc ctcacccgat tccgtcgcta ttgtcacggt
    49201 ctcggttccc ggtggcgagg agttggcgaa acgtaccttc aatccgaaac ttggaattat
    49261 cgggggaatc tccattatcg ggacatccgg aatcgtgcgt cctttctcat cggacgcttt
    49321 tatcgcctcg atacggaaag aagccagtgt cgccaaagcg ataggttgcg agacgttggt
    49381 tattaattcc ggggcgaaga gtgaacgcta ccttcggagc ttatacgctt ctttgcctcc
    49441 acaatcattc gtccattatg ggaactttat cggagagacg ctaaagatcg ctgccgattt
    49501 aggtttcaag caggttatct taggtatcat gatcggcaag gcggtgaaac ttgcggaagg
    49561 tttcctggat acacacagca aaaaagtcgt catgaacaaa ggcttccttc aagatgtagc
    49621 gaaagaagcg aaatgcgagg aggcgaccgt agatgcaatc aatcggatta cgttggcccg
    49681 tgaattatgg gagcttcttg cggaaaaaga acaaaatcgt ttcttcccat tacttttaca
    49741 aaaatgtaaa tcgtattgcg ctcctatcct tcccgacggc gaactaacct tgctgttaat
    49801 atccgaagag ggcaaggtct tgtaccaatc ttagctgtag agacgcagca cgcacgctac
    49861 gtctctacac cccccagact gtaatagcat ttctttttag ctgtttattc ttttttatta
    49921 gggattcttt aagaatacat attaggagga tttcgtactt ttgccctcta aatattgatt
    49981 aaaataatgt ttagatatct tttaatttat atggcctgcc ttctattcgc cttttccgta
    50041 aaggcgcaag gcatttccaa tgacacgatt ctgaaagaag tgctgatgct ggatggtaag
    50101 cctatgaccg aaaagcaaat acaacgttat cataaacaat tacataaaga ctccatacgg
    50161 gccaacaaaa ggatctggtg gtctatcctt ggcggaccgt cttacacgcc ggaagcctcc
    50221 tttggcgtag gtggcgcggt tttggctagc tttcgcttaa acaagaatga tacgatatcc
    50281 caacgatcgt ttatccctgc gggatttaac atcaccttaa acgggacgtt cgtttttgcc
    50341 ggtgccggta ccttattctt caacgagaat cgcttccgta tttatatcag ttacggttat
    50401 cggaacgaac cttcgcatta tttcgggaaa ggctatgaga cgatcgagca aatcgagaaa
    50461 agcgattcga caacgaaatt ccataagagt tctttccaac tatatccccg tttcgtatgg
    50521 gaagttaggc ctcatttata tacgggtcct ctttttgata ttaatttcag caaatcagat
    50581 gatatcaacc cggtgatggc cgaagatcct tatttcaata agttcaaacg agattatgtc
    50641 aatatcggtg tcggcggctt gattcaatac gatacacgaa atgacgtggc gaccccaagt
    50701 tccggtatgt tactaagcgc gatcgctaaa gtgtatggaa agtatttagg cggtgcatat
    50761 aattatgaga tgttcgagtt agaataccgc cagttccagc aagtatttcg tcctcgtagc
    50821 accttggcat ggatcgccaa gacacaaatc ggtgtgggaa acgttccttt tacggagctt
    50881 ccttcgtttg gctctccttt cgatcttcgc ggatactatt ggggcaagta ccgtgacaag
    50941 accatggcgt atgggattct ggagtatcgt catatgttcg gcagcgtgga gaaatataag
    51001 agcggtaatt tctgggcgaa gtgtggtttt gttggctggg tcggcacggg tacgatcgga
    51061 aacgctccta tcgtagactg gaataaatgg aagttcaact acggcgtagg cttacgtatc
    51121 caaatgcaac ccggcaagaa cttccgccta gacgtaggca aagacccgaa ccaaaaaggg
    51181 atggcggttt atatgaatat gacggaagcc ttctaaaacc agaaggctcc cgtctacgat
    51241 ttatggaagt ataaccttgc gttaaaatta tcgtttaaaa gccggaaata tcttaatatc
    51301 gatttttttc actaagtttg cgtcgtcgaa ggggtgccat actatatggg ctgagatcat
    51361 acccttacta cttgatgcgg gtaatgccgc cgtaagaaaa acgaatgtta gatggataaa
    51421 aatgaaacgt accgttatcc ggtagcttta acgatcgcgg gctctgatag tggcggtggt
    51481 gccggaatac aagcggatat taagactttt tcctcgctgg gtgtttttgg agcctcggcg
    51541 ataacggcta taaccgctca aaacacacag ggggtgcgag ggatccaagc gatctctccc
    51601 gagattttga gaggacaaat cgaagctatt cttgaggatt tcatcgtaga tgccgtaaaa
    51661 atagggatgc tacataacaa ggatgccgta aaggtcgtat ctgaaacttt accttccttc
    51721 caacagactt ctatcatttt agatccagtg atgatatcca cgagcggaag taaattattg
    51781 gaggatgacg ccatccgaac catcatggat gagttgttcc ctaaagcgac actgcttact
    51841 ccgaatattc ccgagacgga atatctttcc ggtataaaaa tcaataacga ggcggatatc
    51901 ttacttgccg cccggaaatt gcaggaaaaa ggatgtaacg ctctattgat caaggggggg
    51961 catattcccg gagtagaaac ggtggatcgg ttatttatca atgagaataa tccgatttgt
    52021 ctggtctcgc caacagtgga gaccttcaat acccatggaa cgggctgtac gctatcgtcc
    52081 gccatcgccg cttatatggc actcggccat tcattggtgg aagccgtacg attagccaag
    52141 gaatatatga ataacgcgct cgttcacggg gcaaatgtat gcatgggaaa agggcacgga
    52201 cctgtaaacc acttcttctc accctctgcc cttcataaaa tccgatggaa tcatgaataa
    52261 gctggtcgta attactacac cttatttttt cgcggatgaa gcttctttga tcgaacttct
    52321 atttgcggaa ggaatgtctc gtttacatct acgtaaaccg gattgtaaac gtgatgaatt
    52381 ggagggctta ttggataaca tctctccggc ctattacgac aggatcgttc ttcatgattg
    52441 gtttaccttg gcagaagaaa gggctttagg aggagtccat ttgaacaaga ggaacccgga
    52501 agctccacct ttatataaag gcagtataag tcgttcttgc catagtctgg aagagattat
    52561 cgagtataaa ccggtatgcg actatgtatt ccttagtccg atctttcaga gtatatccaa
    52621 agaaggatat ggtagcggat tccccttaga tggattgcga aatgcgaagg gcatcatcga
    52681 tgataaggtg atcgccttgg gaggaatctg cttacaaaca ataacgaaat taagagatat
    52741 ccccttcggc ggtgtcgccg ttctcggggc cctttgggga aacgatccct cccttcttgt
    52801 tgcggatcaa ctcataaaac aattcaaacg attacaagta tggccttaaa ttattatttc
    52861 ggatatgatg agaatggaag agtcggtcgg agaacaaccg gattacgccc tccttttggt
    52921 gggagtaacc gcttgatgtt tataacgcat cgtacaccta aatatacgga atgcgacgag
    52981 gtacgcatgg caatccaagg aggatgttcg tggatacaat tgcgtatgaa agacgggatc
    53041 tatgaggata ccgtacgtaa atgtgccact atctgcgcgg aagaatgtga gcgaatcgtg
    53101 gatttctgcg taaacgatga tctggaagcc gccgtgacat gtggcgctac ggcttgtcat
    53161 ctaggtaaga atgacattcc cttggatatc gcttgggaag tactgaaaga caagttggac
    53221 tccaatgcca tcttctatat cggggctacg gctaacacgt tcgaggatat ccggctggcc
    53281 gtagaacgag gcgcctcgta tatcggacta gggccgtatc gctttacggg taccaagaag
    53341 aatttgagtc ccatcttagg tctggaaggt tatcgtaaaa ttatcgctca atgcaaggag
    53401 gctggcattg atattcctat cttcgcgata ggtggtatta cgctggaaga cgtaggccct
    53461 ttgatggaga cgggtataac cggaatcgct gtttcgggcg cgattatcaa tgcccccgat
    53521 cccgtggagg aaacccgccg gtttatagag gaaatcaata agtactaaac taaatacata
    53581 tggctactaa aaagaatatg cgtatttcct atccgtcctc ggaaaagatt tatgtcccgg
    53641 gcgagatcaa taagatcaag gttggtatgc gtaagattaa attgttggac acggtaactt
    53701 tggatgagca tggagagcga atcttcaaga agaacaatcc ggtaatcgtt tacgatacga
    53761 gcggcccgta ttccgatccc aagatatcga ttgatatcgc taaaggactt cctcgtatac
    53821 gtgaggagtg gtacggtaag cgtaaagatg tggttcaatt gccggaattg acttccgctt
    53881 atggccgtga gcgattggcg gacgcgagtc tgaattccct gcgtttcccc aagcgatact
    53941 tgcctttccg ggctaaagag ggtaagaata tcacccagat gtattatgcg aagaagcgta
    54001 ttatcactcc ggaaatggag tacgtggcga ttcgtgagaa ccagcaaatc gaggctttgg
    54061 gactgaagtc gtatatcacg ccggagttcg tccgcaagga
//
LOCUS       DBMDTB010000013        52762 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_266_length_52762_cov_12.437952, whole genome shotgun sequence.
ACCESSION   DBMDTB010000013 DBMDTB010000000
VERSION     DBMDTB010000013.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 52762)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 52762)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52762
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_266_length_52762_cov_12.437952"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..578)
                     /locus_tag="ACZPB4_03840"
     CDS             complement(<1..578)
                     /locus_tag="ACZPB4_03840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY-like domain-containing protein"
                     /protein_id="HIR1097384.1"
                     /translation="MNTRLILFTCIAGLTLFFSGCSKNDDDHQGIIPLPPVENAFQEK
                     YPDAKNPVFEIEGNYYVVDFNNEGSETTAWFTDQGVWMMEKIDISFAQLPAAVSTAFK
                     QGFYSNWTVDDTYAINRLNMGIVYKIEAEQSNSEVDLYYSQYGNLIKVVDDEINNDAP
                     IVIPKEVSNLMEITFANAELLDIQQNSLGYEL"
     gene            complement(711..1877)
                     /locus_tag="ACZPB4_03845"
     CDS             complement(711..1877)
                     /locus_tag="ACZPB4_03845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097385.1"
                     /translation="MKKVLYYLIIMLAFTLNACDNEMDNMQGGDKEILTSSSEIVIKD
                     GKITYPKWLVNVVDSVAHSHVKGTDYPYPWVFTIQGDGKEHILVLDGVNSCASCGQLL
                     FLLSGERIEKFPNEWITMENLNMIWEPNLNVETKAQGAAATVYTPNGTLVNDTYYRSE
                     ELSASQKASHDQYCTTTYSQATLISSSTTTYNCHAYAWYMTEGGSAVWMGWTINPTNV
                     YWLDGSYISTTGAATKVSYLSDNHSAVTTSTPNIFISKWGEYALMRHPKAHCPFDASS
                     LKYMKKNDMPTVYIGKSQEDYSSGSSSINAPGGNATTTLYAYTKTGTPTSYSWNAEFY
                     GECDRWYTYPSGNRLDVSVYLNSQHYGGSLRITCAMYNGSSLIGTATYYLNVNP"
     gene            complement(1874..2602)
                     /locus_tag="ACZPB4_03850"
     CDS             complement(1874..2602)
                     /locus_tag="ACZPB4_03850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097386.1"
                     /translation="MKKTVTFVWSIFLLVFISIDMNAQSIKSWDYPIKPGTEAWQALS
                     THEDMLKACQIPAEILKTVSTEELIELCLAYPLLGDIFAYNGIQEGISKVSARFNGLQ
                     ELFKRKDNASLLFEKMKKQELLKAGVLTSIEIGNEISRQMVIEALLSNETILSNTNNL
                     LQQEISSEAVKRLLYKQNNPDIYGQYGLKTVVYLLGRSLERIDNKTITPKFKQFTIDE
                     KLTGSNVIEELLKQYIVTFNKLRS"
     gene            2883..4127
                     /locus_tag="ACZPB4_03855"
     CDS             2883..4127
                     /locus_tag="ACZPB4_03855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HIR1097387.1"
                     /translation="MDREISKEVRQKEQRKQFIKLGAGIGIAVVLIGGVIGFMQTSLQ
                     RKDLVFSTVDKGVIEVSVSASGKVVPAFEEIINSPINSRIVEIYKKGGDSVDVGTPIL
                     KLDLLSAETDYKKQLDEEQMKRLQLDQLRIQNRNKLSEMEMQLKVSRMELNRKEVELR
                     NERYLDSLGAGTTDKVRQVELDYNVSVLKLKEDEQKYENEKSLTDADYKVKELDLNIF
                     RKSLAETKRTLEDAQIRSPRKAILTYVNNEVGAQVSQGSRVAIVSDLSHFKIEGEIAD
                     TYGDRIAAGSKAVVKIGNDKLDGVVSDVTPLSKNGVISFTVQLEEDNHRRLRSGLKID
                     VYVMNAIKDDVLRISNASFYVGKGEYELFVVNGDQLIKRKVQLGDSNFEYVEVVGGLE
                     PGDEVVVSDMTSFKEKNKLKLK"
     gene            4139..5410
                     /locus_tag="ACZPB4_03860"
     CDS             4139..5410
                     /locus_tag="ACZPB4_03860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1097388.1"
                     /translation="MYKQYIKQAVLMLRENMLVSVISISGTALAIAMVLVMVLVFQIK
                     STGYAPESNRSRFMYVWGTEVGSKSPGGSDRNRGGMSSEVVKECFYTLRKPEAVSGYC
                     SDSHSLSLPNRRLFKEYEICYTDAGHWKIFDHPFVEGGPFSEADFQSGIPKMVLSEQV
                     ATDLFGTGQAVGRQVVMDFITFTVCGVVRDVPSSLMSSYAQVWIPYSSNEALTRVNGE
                     YGENMAGYFSVALLARSSSDFDAIRSELDQQVRRYNDSKTDYNVGFPSGLLSQLDTAM
                     GSGAFQKVDWPTFLAGSGTFLFFLLLVPALNLTGVIQSSVQKRKEEIGLRKAFGATGQ
                     NLLMQILSENFVLTLIGGVIGIGLSMVLLVVGKPFMLSENVSLTAPMLIKPGLFISAL
                     IFTFLLNILSAGIPAWRTTRQPIVEALKGNE"
     gene            5466..6734
                     /locus_tag="ACZPB4_03865"
     CDS             5466..6734
                     /locus_tag="ACZPB4_03865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1097389.1"
                     /translation="MIKHIFKIIWAQRKSNGWILGELVIVMCALWFMMDKLWVDVRCY
                     NAPMGYDISNTWRFKLSTLSSNAPGYVPDSLYDSNATQDLLKLMERIRQEQEVEEVCV
                     TYWSMPYSNGSSWGTLLPLGADTSKAVGQNYHKLKVSPSYFDVFRMKDKEGRAITPLV
                     ENAYRPLVITAEAEDFFFGGQSAIGRQISENDDLSEPFTIAAVLPTFRSNDFDRPENC
                     AFTILKGESLQEFVKNFGVRSAELSVRTKRPMTEDEMYAFLEKTADRMTVNNTFVHGV
                     TLLADQRDDQLRFTKNENSKKLSMMAFLLVNVFFGIVGTFWLRTERRRSEIGLRMAIG
                     SSRGRLGEYMYLEGLGLLAITVPILLVFVFNMAFLDKLDSYREPLSILRFLVTLSVSY
                     LLMAGMICMGIWFPVRKAVKMAPAEALHYE"
     gene            6785..7066
                     /locus_tag="ACZPB4_03870"
     CDS             6785..7066
                     /locus_tag="ACZPB4_03870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097390.1"
                     /translation="MTAIELKMSLLQEVMSLEDEQLIKKALDSVRRMKMAAFGKATPV
                     EKPADDYAEPTKEEILAGLRNALQDVKDLREGKDVGHKFRDLSELLNEV"
     gene            7056..7406
                     /locus_tag="ACZPB4_03875"
     CDS             7056..7406
                     /locus_tag="ACZPB4_03875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module toxin RelE"
                     /protein_id="HIR1097391.1"
                     /translation="MRYRIKTHQDFDKEFKRLCKKYSSLKADLSALGKSLSENPDQGT
                     SLGKGVRKVRMAIVSKGKGKSHGARVITYTEAIVCADNEGTVILLTIYDKADRDSISA
                     AEIDELLRSLRWEL"
     gene            7605..8867
                     /locus_tag="ACZPB4_03880"
     CDS             7605..8867
                     /locus_tag="ACZPB4_03880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1097392.1"
                     /translation="MIKQYIKQALRMIGENKLLSVISILGTALAICMIMVIVILYVVN
                     TASFKPEVNRGRTCYITTVMSNGKDDNRRISYSSLGLPLVKECCYPLKGAEAVTAINM
                     DRYRPLTASSMDGLKNRTSYISYTDTAFWKIFQFDFQQGGPFSPAAFTSGIRDAVISE
                     SVALALFGTDQVVGREMKLDFIVYNICGVVKDVSRFASKAWAEVWIPYTVRDDGGYQE
                     GINGSYSCCVLLRPGVTREELRTEALRKVEEFNAKTRDVKADILHQPSTQIEEWIGGG
                     SEFGANLFYLYVRYGIILFILLLVPALNLSGITLSRMRRRMAELGVRRAFGATQGTIL
                     WQVLSENMVLTLLGGLLGLAMSYGAMLLLRDWLLVTSLGKTGLSTGMFNGAVFIAAFL
                     FCLVLNLFSAGLPAWRMSRLNITDSING"
     gene            8872..10143
                     /locus_tag="ACZPB4_03885"
     CDS             8872..10143
                     /locus_tag="ACZPB4_03885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1097393.1"
                     /translation="MYKMILKQLWNERKGNLFIWLEMLVVSIFLWYAADALFVMYRLY
                     SQPLGFNIEHTYHVSFGVIPEESPDYDTTSVHSERGGGDYLTLMDRIRRNPSVESICF
                     TTGVHFHYRGSNQYATFRKDSLIRNGFVRFVSPTYFEVFGVKTAEGGSPSELVDALRD
                     NQVVVTGRVADDFFGNPAAAVRQEIYITNQGSRDSVAYRIGGVCEKQRYCEFTGYDYA
                     YYKLVDENKVAEEGDWVGEGLNTFIRVKPGADGAAFATNFRKEMEQQLRVGNIYLKDV
                     FPMSHYRDQFLERWLDQVRLYVAGIAFFLLNVLLGVVGTFWYRTQQRSAEIGLRMAMG
                     ATRKGIFWQLVKEGLALLTIAFIPSTVIFANLLHMEVTQGSEIPPDMASRLLFGFVFS
                     YAVMAAMIVVGISFPSYRAMRMHPADALRQE"
     assembly_gap    10274..10373
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            10535..11200
                     /locus_tag="ACZPB4_03890"
     CDS             10535..11200
                     /locus_tag="ACZPB4_03890"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008999908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1097394.1"
                     /translation="MIKLTNLQKIYRTKEIETVALENVNLEVQQGEFLSIMGPSGCGK
                     STLLNIMGLLDLPTSGTVEINGVNTVGMSDKELAAFRNKQLGFVFQSFHLINSLNVLD
                     NVELPLLYRKVSSSERRKLAEAVLEKVGLSHRMRHFPTQLSGGQCQRVAIARAIVGNP
                     DIILADEPTGNLDSKMGIEVMDLLHQLNKEDGRTIVMVTHNEAQAKQTSRTVRFFDGR
                     QVQ"
     gene            complement(11348..12133)
                     /locus_tag="ACZPB4_03895"
     CDS             complement(11348..12133)
                     /locus_tag="ACZPB4_03895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding domain-containing protein"
                     /protein_id="HIR1097395.1"
                     /translation="MDKELPKSELPKPFRKLSLRVSKSHLPGNASYKGSVVWQRTLSI
                     DDIAARVVDKRSEYRKETLITTFNLLKREIYDAIEEGYNVDFGFGRTELTVNGPFESL
                     YEKFDPNRHTLAPRLRPAPELKQRVANLRAVNETYQLDYNSQPRPAYVSLRIQPRTPD
                     CDEPYNQLPAGEHHFISIYGDRLKLMGDDPRVGLYLHRPDGSEEHFYPPSEVFINTGK
                     RLCFTPGFAFTDGEWVAEVVTQYTPNSRPYKQPRYGTLTFLVR"
     gene            12198..13490
                     /locus_tag="ACZPB4_03900"
     CDS             12198..13490
                     /locus_tag="ACZPB4_03900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1097396.1"
                     /translation="MYKIYIKQAWALIRQERFFSSVYIVGTGLAISMVMALAVAYHIR
                     TANIAPEVHRDRMCYLSNVTYKLNGTKSNYKAACGPRLVKEVIGNLRVPEDVAVTTNS
                     FMMPFSYGDAFMRLPGGDESPKVRLKGCDDGFWRVYRFDFVEGRPFTEAEFLSGMPRA
                     VLCRSLAGRLFGHEAAAGQTILLNGLEYTVSGVVDDVSGITADVYAEAWVTYSSLSVA
                     MDHALGERDGAVGLLEANILLADASDLPALSEELRREVRRYNSGLSEGQVVCEEPLSY
                     ADNLLSGLFGPETYIVLGMALLLFLLVPALNLSGMNASRIQERVGELGIRKAFGATKA
                     TLMGQVFVENMVLMLPGGVAGLLFSYVLVFIFRNALLVPGFNLLGTSGDVFLSPGMLL
                     NMSVFAYAFGVCVALNLLSSMLPAWRIVRGNITDALNG"
     gene            13506..14765
                     /locus_tag="ACZPB4_03905"
     CDS             13506..14765
                     /locus_tag="ACZPB4_03905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1097397.1"
                     /translation="MIIHILKLIRSRMGGSGWILAELLVVFVVIWFMTSYFLMMGKSW
                     YEPVGYDLEGVYHAVLAVRPSNSPSFVTYEEGGDEAARDVERIVERLRGHADVEAVAL
                     SVSSLPYTLSWSGSRVTRDSVSVSVRLMTVSPDYFRVFGIRPASGESPERLGEALSGT
                     REGRDRVISAELARRLYGTTDAIGADIYLHGDTLPGHVVAVTGPVRNDEFDRRKQCIL
                     FSLLDLRELNDLTQVQITFRLRPSVATAGYADRFLKAMKRQLMVGNFWVSEVRAYPDV
                     RSSYLENSIESNAQRIVSALGLFLLTNVFLAVIGTFWFHVSRRRAELGLRMAMGSTRA
                     SILGLVMGEGLMLLTIATVPALLICVNLAWIDLMPPGLVESKVGCFLINSLLTWLILA
                     LIISLATWYPARKASSLEPADALRYDG"
     gene            14835..16154
                     /locus_tag="ACZPB4_03910"
     CDS             14835..16154
                     /locus_tag="ACZPB4_03910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1097398.1"
                     /translation="MNMYKIYLKQAWALIRQERLFSSVYIVGTGLAISLVMVLSIVFY
                     VKMASIYPEMDRNRLLTVKSAALKNEKGGTSSGPVSPRFVEECLAGVPGLEALALCCD
                     DAASAFVQPVGSPVQIPVMKMGVNDGFWKVFSFRFLEGKPFTEADFRSGMPVAVIARS
                     LAKRLYGEGSAVGQTLSLDFTSFRVVGVVDDVSYLMDRVFSQVWYPYTQVPDFEERVR
                     YSEARMPGLGPLKVYMLVKDKADIGKVREAVADNVRRFNQSLNVDGKREFSLLGQPDR
                     HWESIFRYWSNVEPDIVGDLSRYGVIFLLLLLVPAVSLSGMADSRMERRLGELGVRRA
                     FGAPKGALIGQVLMENFLYTLLGGLVGLLFSFLLVTFASSWVFKIGNGFSDAAPDGVD
                     VSLSMGMLFNPWVFLIALCVCFLLNLMSALWPAWRASRRPIVDSLNA"
     gene            16172..17470
                     /locus_tag="ACZPB4_03915"
     CDS             16172..17470
                     /locus_tag="ACZPB4_03915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010183776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1097399.1"
                     /translation="MWKITWIQLMNRWRSNVWVCVELLLAFCLAWYMADYFFVEIYNR
                     SLPSGRGYADVWQVEMGLLPETSPDYRVAESDSIAMLGNYERIKDRLCDYPGVQAMGA
                     ASECYSTPYTGCYYGIGLANAADTSKREAVMRYEIDPTTDFLSVFNHSYAKDGRPVST
                     SDFDWGDPRAIVTTRMVERKVFGEASAVGREVKDPFDEEGPTYIVKGVLEDIKRFDNS
                     LPQGAAFLAIRPSAEEIPEMNYFIRIDPAVAGPRFADTFREKMSRELRVGNFYLKRLT
                     SYERIKADTDYSFGVTYDYRVRMALMAFLGLNILLCVMGTFWYRVRMRRGEIGLRMAI
                     GSPREEIRSQMAREGICLLLMATPLALLIEAQFVMVGFLDIPKGTLPELYWPAILPLR
                     FLLVNILTWILLAIVILLAVWLPASKAAEMEPAEALRYDG"
     gene            17524..18813
                     /locus_tag="ACZPB4_03920"
     CDS             17524..18813
                     /locus_tag="ACZPB4_03920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1097400.1"
                     /translation="MYKIYLKQAWALLKENKLLSGVSIFGTALAICMIMVIVIVWQIR
                     TANYSPEDYRDRMMYVSDTRASYKENESYNDCYLLASRVVKDCFYPLRSAEKVGMAYH
                     GVQRLAAVADHTVEFKCDVTFTDAAFWNIFNFRFLSGKPYGEEEVQSGIMDAVVSESV
                     ARRLYGTTEVVGRTVEISYVPYTIRAVVRDVSLLAESAYGDVWLPYTTDNSLYDDSSD
                     RLIGGFRCYILASSSADFGAIHSEAEANIARLNESQSTHLLRIGGAPDTHLGDLARED
                     AFSEPNVRELVLKYVIIVLVLLLIPAINMSGITQSRMRKRMAEIGVRKAFGATRSELL
                     TQVLYENLLQTLLGGVLGLFFSYASVLLLSDWLLDTGTASMGIGRTFVNAEMMFNPLI
                     FLYAFLACLALNLLSAGIPAWRASRMRIISALNENVH"
     gene            18857..20119
                     /locus_tag="ACZPB4_03925"
     CDS             18857..20119
                     /locus_tag="ACZPB4_03925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1097401.1"
                     /translation="MIRHLLQLIWNQRKQNAWLWAELLLVSVFLWFLVDYLYVMGRTY
                     TAPLGFDIRHTYSIVISSLSERSPDYIPKEKRERPDGVHLLTALDRIRTYPGVESACL
                     TDGGMPYYMGSRNLVWRIDTLQVPCRYAFVTPEFFDVFRIYDKEGETASLKRAIEDNN
                     SIVISADVETMNPGLSLLGQKAYRGNVTDEIEETIRGISVPIRRHEYTKAEPNVYRAL
                     RLSRMEEGYYEGMIDAVRLCVRVRPDVDNADFPARFRKDMAEQLRLGNLYLLDVQPLS
                     YIRDGYIRSIGVENEVKTRVAVACFLLANIFLGIIGTFWFRTEYRKGEMGLRMALGST
                     RRQLNSIMVGEGVLLLVLAFIPSLVISFNIAHMDLIDTYQLPFTWLRFAICGGITFVL
                     IVLMIICGVWYPARSTARLEPAEALHYE"
     gene            20309..21577
                     /locus_tag="ACZPB4_03930"
     CDS             20309..21577
                     /locus_tag="ACZPB4_03930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1097402.1"
                     /translation="MLKESPFFSVITILGTALAICMIMVMVIVFEIQNKGFKPELNRD
                     RTLYVKDVAITHKNEEDGGMNYSLVGGRVAKECFFTLKTPEAVSMQLMRMQTLVTSTD
                     QTRRMKCDQIRTDEGFWKIFDFEFLAGKPFLRSDVESNIKKAVISRRLALRIFGLADE
                     SVIGQTILVARRPYVVGGIVEDVSPLANRAYAQIWIPYAQSDVDRLINEETLEGLIGS
                     YRVLILARSSGDFNKIKTEVEQNVARFNNSLQELKIDLMKQPDTQMESRLRLWSNVVP
                     DVPRMLGQYALVLIVLLLVPAMNLSGLTASRMQKRMGELGVRKAFGANRGTLIRQVLA
                     ENLAVTLLGGVLGLLFSYVAVFLLKDWLLGSFELASLNSGLTLSAGMLIRPAIFFFAF
                     LFCLLLNLLSAAIPAWNASSGNIVDSLNDK"
     gene            21614..22855
                     /locus_tag="ACZPB4_03935"
     CDS             21614..22855
                     /locus_tag="ACZPB4_03935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1097403.1"
                     /translation="MIKHLVKIIWNQRRRNGWMAAEILLVFVVLWYIIDSLMAVGKVF
                     FAPMGWDIDHVYWISMGVEEVDRNEMDSTYRYVTSGRSMLTAIDRIKTCPGVEAVGAG
                     LMSMPHTGENRYMQVDVNDSINVEYVKLLEVTPGFLEVFNFRPMEGEKKDWEEMLNGR
                     QVVLSAGLFREFQEKGGKRDEGISFWGDRRSIGGVTADFRADRFTKSCSWLFMPLTDE
                     EIAEDDTDFHVKIAVRVNPSADHDFPEFFVKQMEKQLSIDRLYLLDVIPYSDLRYSME
                     LRNGVKSELQNQIAVMGFLLFNIFLGIIGTFWFRTEQRKGEMGLRIALGSTRFSLKGI
                     MIAEGVLLLTLIAVPALLICFNLHVSELTKGFYMDYTIARFAAGFLITYLVMAVMIIL
                     GIWYPAHQMARLEPADALRYE"
     gene            complement(22955..23512)
                     /locus_tag="ACZPB4_03940"
     CDS             complement(22955..23512)
                     /locus_tag="ACZPB4_03940"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016791 - phosphatase activity [Evidence
                     IEA];
                     GO_process: GO:0006644 - phospholipid metabolic process
                     [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HIR1097404.1"
                     /translation="MRHILFAITMLMLCLSVNGQELKVTGSRKAVRTSGDVLVFITPV
                     ASLATVLATQDWQGLKQGVFTGVTTLGVTYALKYLVKKERPDFSDNHSFPSMHTSVSF
                     AGAAFIQRRYGWKWGIPAYAVSTYVGWSRVYGKKHDWWDVAAGAVIGAGSAYIFTRPF
                     AKKHNLSISPVAGDGHYGVYASMTF"
     gene            complement(23517..23894)
                     /locus_tag="ACZPB4_03945"
     CDS             complement(23517..23894)
                     /locus_tag="ACZPB4_03945"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0001727 - lipid kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HIR1097405.1"
                     /translation="MKNDGFTFRKRARSFKFAFNGIKLLITKEHNAWIHCFAAVCVLI
                     AGMVFGLSRMEWIAVTIVIGAVLAAEAVNSSIEALADLVSPEYNEAIKRTKDLAAGAV
                     LLMAIAAAIVGFVIFIPKIATIF"
     gene            24113..25153
                     /locus_tag="ACZPB4_03950"
     CDS             24113..25153
                     /locus_tag="ACZPB4_03950"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1097406.1"
                     /translation="MKIKYNFLSPLLMAILTICCLWIVTDVAYGVRMWELGVDAWIGR
                     IKALAIILIGVSLSYLFFNYLANTFLDRNKERRSRPVFREYLWVVLFNLVVLNIGLYI
                     VIYSINGTTYRWGEALMINAVAVPIFLLYYFLIRNNILAKRYSEKIVQLEKLRVDQLE
                     TQLKLLKMQYHPHFLFNALNTIYFLIDEENEEAIEAVELLSDLLRYQLYDINTKVTIE
                     EEIDYLRTYIQFQRLRMTKRLQFEESFDPELTGQKIHPLLFQPLLENAFKYIGGAYRI
                     QVSMRKEGAKVCLGVSNTFNPDFLEQRKGKGIGIDNLRKRLELLYPDKHELRIKKDNT
                     RFRVELCIDLSE"
     gene            25155..25859
                     /locus_tag="ACZPB4_03955"
     CDS             25155..25859
                     /locus_tag="ACZPB4_03955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HIR1097407.1"
                     /translation="MEIKCIITDDEPIARKGLRRHIGKIDFLTIVGECEDAIQLNNML
                     NSVQADLLFLDIEMPDMSGLDFLESAQNAPKVIITSAYERYALRGYEFDVVDYLLKPI
                     SFSRFLKSVNKAHALMESTSKSEEPAYIFVKTEKQLKRLYLKEIQFIEGMENYIVIHT
                     LTSKEIVHLRLKSIQETLPAQIFMQVHRSFIVNLSYVQAIEGNLLIIGEHKIPVSRPL
                     REEVYKSIVNNQLIQR"
     gene            25985..27469
                     /locus_tag="ACZPB4_03960"
     CDS             25985..27469
                     /locus_tag="ACZPB4_03960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HIR1097408.1"
                     /translation="MRRIYIAMCCLWAGISGVCAQDNTNKVRITLRQAIQIAQLQSVD
                     AAVALNELRTAYWEFRTHRADQLPEVIFTGTLPSYSKQYSKYQQSDGSYTYVQNNALG
                     LNGEISIAQNIALTGGKIALNTSLDFTRQLGSGAYNEFMSVPVSLTLTQPIFGVNDQK
                     WKRRIEPVRYQEAKAAYMENVENVTIATITNYFNLLLAEDNLDICNQNLLNANKLYDI
                     AVAKRKIGHISESELMRLKQSALQAKGKLTEAQSNYNAMMFKLRSFLGMSEQDVIEPV
                     LPEAIEGVRMDYQAVLEKAQENNSFSKNIMRRQLEADYDVATAKGNRRSINLFASVGY
                     TGKDMSMRGAYNPLKDNQIVEVGLSIPILDWGKRKGKVKVAESNRDVVLSKIRQEQMD
                     FNQDIFLLVENFNNQAAQLEIAAEVDTLAEKRYKTSIETFMIGKIDILDLNDAQSSKD
                     DAKQKHIQELYYYWRYFYNIRSITLYDFLNNRTLDADFEEIVKR"
     gene            27479..28849
                     /locus_tag="ACZPB4_03965"
     CDS             27479..28849
                     /locus_tag="ACZPB4_03965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent transcriptional regulator"
                     /protein_id="HIR1097409.1"
                     /translation="MILIIDDDAAVRSSLTFLLKRAGFRPEAVPGPKEALEVVRATAP
                     ELILMDMNFTLTTTGEEGIQLLRQVKIFRPDVPVILMTAWGSISLAVQGMQAGAFDFI
                     TKPWNNLVLLKSIRTALELSEQKKEANAPLNRSDADHKFHFDKIVGQSAALMDVLGTV
                     SRIAPTNASVLITGESGTGKELIAEAIHANSPRSKEAFVKVNLGGLSQSLFESEMFGH
                     KKGAFTDAYMDRVGRFEMANKGTIFLDEIGDLELSCQVKLLRVLQDQTFEVLGDSRPR
                     KVDIRVVSATNRDLRSMVADRTFREDLFYRINLITVHLPALRERREDIPLLARYFADK
                     QSEINGLPRVEFSSDAQTYLSRLPFPGNIRELKNLVERTILVSGKTLLDTADFEVHCM
                     NTSGAKSTIPPSLEGLTLDELEKQTILRSLEAHGGNLSHVATALGISRAALYRRLEKY
                     GIPIDK"
     gene            28862..30163
                     /locus_tag="ACZPB4_03970"
     CDS             28862..30163
                     /locus_tag="ACZPB4_03970"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1097410.1"
                     /translation="MRLKGLFWILTTLLLTILAVVTYYVFYTSSIRMFFAVEALVLLT
                     IIYLFVFYRRIIKPLHIIGNGMELLKEQDFSSRLGKVGQTEADRVVDVFNKMMEQLKN
                     ERLHLREQNHFLDLLVNASPMGVIILNLDEEILSMNPAACKLFGAQSSEDMVGKRFLQ
                     LDSPLAEELVRVPMYQAQTVRLNDANIYKCTHSSFVDRGFHHPFYLIETLTQEVFKAE
                     KKAYEKVIRMISHEVNNTTAGITSTLDTLESTFSGMEDMEDVCEVLRVSIERCYSMSH
                     FITNFADVVRIPEPQSRPQELNQVVSACKRFMETVCQNRNIEIVMDLSEESPVVNLDN
                     SLFEQVLVNIIKNAAESIDRDGKIYIRTTVRPTCLEIADTGKGIDKETETKLFSPFFS
                     TKPNGQGIGLIFIREVLLKHDCRFSLRSYADGLTRFKIWFS"
     gene            30474..30866
                     /locus_tag="ACZPB4_03975"
     CDS             30474..30866
                     /locus_tag="ACZPB4_03975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Dabb family protein"
                     /protein_id="HIR1097411.1"
                     /translation="MKKVVSVLFILAIIVFSVLMVSYSSDQKPEKVLRHVVMFGFKPD
                     VSEAQVKEVEDAFCKLPSQIDLIKGYEWGTDCSPEGLQQGLTHCFFLTFHSDADRDAY
                     LVHPAHKAFGKVLGGKASAVTVLDYWTK"
     gene            complement(30932..32029)
                     /locus_tag="ACZPB4_03980"
     CDS             complement(30932..32029)
                     /locus_tag="ACZPB4_03980"
                     /EC_number="2.7.-.-"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase enzyme family protein"
                     /protein_id="HIR1097412.1"
                     /translation="MAKTKEQLLNILDQFQLDEKVVSAEPFGNGHINDTLKVTNEKGE
                     IKYVLQRINHLIFTNVDMLQNNIHVVTTHIRKKLEEKGETDIDRKVLTFLPTKDGKKY
                     YFDGDSYWRVCLFIPRSKSYEEVTPELSYEAGKAFGDFQTMLSDIPEGTLGETIPDFH
                     NMEFRLRQFHEAVAANPAGRLEEVKDLVEEIEKRAEAMCIQERLYREGQLKKRTNHCD
                     TKVNNMMFDADSDKVLCVIDLDTVMPGFVLSDIGDFIRTGANTGAEDDENLDNVNVNM
                     EIFKAYTRGYMEKAKAFLTPTEIKLLPYGGRLLTYMQTVRFLTDYINGDTYYKIHSPK
                     HNLIRTKAQFKLLQSLEAHAEEMDQFMNQWL"
     gene            complement(32119..32373)
                     /locus_tag="ACZPB4_03985"
     CDS             complement(32119..32373)
                     /locus_tag="ACZPB4_03985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007212861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HIR1097413.1"
                     /translation="MKKGIHPENYRPVVFKDMSNDDVFITRSTINAKETIEIDGVTYP
                     LVKVEISNTSHPFYTGKSKLVDTAGRVDKFMSRYGNRNKK"
     gene            32597..33595
                     /locus_tag="ACZPB4_03990"
     CDS             32597..33595
                     /locus_tag="ACZPB4_03990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008155377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HIR1097414.1"
                     /translation="MVNYKDLGLVNTKEMFAKAIKGGYAIPAFNFNNMEQMQAIIKAA
                     VETKSPVILQVSKGARQYANATLLRYMAQGAVEYAKELGCPNPQIVLHLDHGDTFETC
                     KSCIDSGFSSVMIDGSHLPYEENIALTKKVVEYAHQFDVTVEGELGVLAGVEDEVSSD
                     HHTYTNPEEVIDFATRTGCDSLAISIGTSHGAYKFTPEQCTIDPVTGKMVPPPLAFDV
                     LDAVMEKLPGFPIVLHGSSSVPQEEVETINKFGGALKAAIGIPEEWLRKAAKSSVCKI
                     NIDSDSRLAMTAAIRKTFAEKPAEFDPRKYLGPARDNMEKLYKHKIINVLGSNDKL"
     gene            complement(33666..35672)
                     /locus_tag="ACZPB4_03995"
     CDS             complement(33666..35672)
                     /locus_tag="ACZPB4_03995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluzincin family metallopeptidase"
                     /protein_id="HIR1097415.1"
                     /translation="MRKQVVRICMLLACAFSFMQGQASIQPSIVKATIDELIAKDAKN
                     QAGITKGVEQVARLWQTSDGDEQAFQTFCRENYLSDPAEKDQVFLKISEYIEGINGNF
                     NEMVLCLQRNLNLDTGPLHAIDEKFGSYSPSSHLMDDLYANKIGFIIALNFPQLTLKE
                     KEALGNDRKAWAYARLGDMFTERIPAEVKQAAADTESDADIYIADYNIYMGHLLTPKG
                     KTIFPSDMRLLCHWNLRDEIKANYNKGKEGLEKQRMVYEIMKRIISQEIPKEVINSDR
                     YEWNPYANTLSQAGNELEGTPESPARYQKMLNNFNAMQRIDKYTGNTYIDRKFTEDME
                     IDVNDVEALFDQFLSAPELKEVGKIISKRLGRKLEAYDIWYDGFKARSNLDENKLNEQ
                     TRTLYPDAVTMEKKLPEILQKLGFSPDRAQYLADKIAVDPARGSGHAWGASMKGQRSR
                     LRTRIPSQGMDYKGYNIAIHEFGHNVEQTISLYDVDYYMLNGVPNTAFTEALAFVFQK
                     RDLELLGIKDENPEKEKMDILDKIWSMYEICGVSMLDISVWKWMYAHPNATAGELQEA
                     VIRLSKEIWNKYYAPVFGVKDETVLAIYSHMIGYPLYLSAYAFGQIIEFQLENYLNGK
                     DFANEVSRIFKQGRLTPNVWIKQATGNDLTVDPMLEALRKVLKD"
     gene            35762..36385
                     /locus_tag="ACZPB4_04000"
     CDS             35762..36385
                     /locus_tag="ACZPB4_04000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4923 family protein"
                     /protein_id="HIR1097416.1"
                     /translation="MKKLLCMWMVVCGLLLIPGNMKGQSLKDILNSSAVKNAVTSVTG
                     GKAVTFENLQGTWMYVNPALQLEGDNALKNVAGSLAATEAEKKMKEYCAKVGIVEGVF
                     NYVFNSDSTFTSALKRGSLKGTYSVSPEDKTVTLRYTVGNKKLTVSTLTAHVVLSGNE
                     LTLLFNADKLLKFLSTVSSISSNTTLKAINKLASEYDGMMLGFDLKK"
     gene            36392..37759
                     /locus_tag="ACZPB4_04005"
     CDS             36392..37759
                     /locus_tag="ACZPB4_04005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HIR1097417.1"
                     /translation="MIRFIPRRYWAVIAVALALTMSVLDGTIVNVALPTLSREFGTSP
                     SSTIWIVNAYQLTITMSLLSFSALGDIYGYKRIFLIGTTIFCSTSLFCALSSSFAMLT
                     VARILQGIGASAIMSVTTALLRIIYPPQYIGRGMSINAMVVAVSIAAGPSLAGAILSV
                     ASWNWLFAINVPLGICAIITGYFLLPQNPCKDGPKRKFDKIGGISNALTFGLLIYSLE
                     GIAHHENWRMIALQVLLLLVIGTFFIRRQLRQEVPILPLDLMRIPIFALSVLSSITSF
                     TAQLLAMVSLPFYLQNVAGRNEVETGLLLTPWPVATILTAPVAGRLIEKYHPGLLGGI
                     GMVVYATGLLLLALLPGQPTNMDIAWRLMLCGMGFGLFQTPNNSTMISAAPRSRSGGA
                     NGMQGTARLLGQTLGTTFVALIFSVTSATDSMPVCMYVAIGFALVAAIVSCLRISQPV
                     PMRGR"
     gene            complement(37730..39874)
                     /locus_tag="ACZPB4_04010"
     CDS             complement(37730..39874)
                     /locus_tag="ACZPB4_04010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HRDC domain-containing protein"
                     /protein_id="HIR1097418.1"
                     /translation="MMQTNLQLDLAFNYLENTGTNIFLTGKAGTGKTTFLKKLKETSP
                     KRMIVVAPTGVAAINAGGVTIHSFFQLPFGPYIPGSEMASGQNKSYSHKFSRDKINII
                     RSMDLLVIDEVSMVRADLLDAISDMLRRYRDRNKPFGGVQLLLIGDLQQLAPVAKEDE
                     WNLLREHYASPFFFDSKALSESDYLCIELTQVYRQADDTFVRLLNNIRENRFDENTLH
                     TLNQRYIPNFKPNDKAGYITLTTHNYQAQQINNRKLQELPGPAYTYKAEIKDDFPAYS
                     YPTDEVLELKQDAQVMFVKNDSSGERRYYNGKIGRIVFISPSKIIVSDELGNDITVDR
                     ETWTNVKYTIDENTKDITETIAGSFSQYPLKTAWAITIHKSQGLTFEHAIIDASAAFS
                     HGQVYVALSRCKTLEGMVLSSPITRNAMISDEKILSYTSSLSERQPCEDQLRQAQQQY
                     YLRLATELFDFNPVQQKLQYTSYAAYTHLQKLYPELSNQYPRVRDYFRSDIVEVGERF
                     CQQLTRMISSTNLYDTDEHIQDRIRKGCAYFLEKIETYCLPLIEASDVEIDNKEARKA
                     FTSALKAFSDELTIKVATLKACQDGFRLIDYLSAKAKANIEESAVASKQKSTRKSTEA
                     EKIPVSTDVLHPELYARLKQWRYELAVEKELPPYTILQQKALIGVCNTLPTNSKELLK
                     IPGIGKKIIENYGETLLEIVSSYSPSTHGNGL"
     gene            complement(39967..40329)
                     /locus_tag="ACZPB4_04015"
     CDS             complement(39967..40329)
                     /locus_tag="ACZPB4_04015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HIR1097419.1"
                     /translation="MNIEEFREYCLSLNGVYEKMPFTNVPDKYSRDVLCFYVGSKWFC
                     FVNIEVFDFCCIKCDPNESGELQARYSGITPGWHMNKKYWISVYFNQDVPDNKIKELI
                     KQSYDIVYQSLPKKEKGM"
     gene            complement(40351..42318)
                     /locus_tag="ACZPB4_04020"
     CDS             complement(40351..42318)
                     /locus_tag="ACZPB4_04020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046556 - alpha-L-arabinofuranosidase
                     activity [Evidence IEA];
                     GO_process: GO:0046373 - L-arabinose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-arabinofuranosidase C-terminal
                     domain-containing protein"
                     /protein_id="HIR1097420.1"
                     /translation="MRRKNMKKTAALFLLSVGVNCMTAQDIVPVHEFDIDIQKVGSPI
                     QSTMYGIFFEDINFGADGGLYAELIKNRSFEFENPWGGWEPFGDVSIAEKNPCFNKNP
                     HYAHLTYTGQITGTGLENEGFKGIGIKADENYDFSLYARTETNNPIKLRIELVNRDND
                     IYETQHLEIKGKDWKKYSVILSPKATEAKSRLRITMETAGTLDMEHISLFPEKTFNNR
                     TNGLRRDLAQALKDLKPGIFRFPGGCIVEGTTIATRYQWKNTVGPVENRPINISRWNY
                     TFPHKKFPDYYQSYGLGFFEYFQLSEDIGAEPLPVLNCGLSCQFENEGMDQHVPVDKL
                     QPYIDDALDLIEFANGPITSQWGKVRADMGHPASFNLKFIAIGNEQWGPLYPERLEPF
                     VKAIRAKYPEIKIIGSSGPDSEGKDFEYLWPEMKRLKVDLVDEHFYRSPEWFLNSAKR
                     YDSYDRQGPKVFAGEYACHPTNRENSFLTALCEAAFMTGLERNADVVELCTYAPLFAH
                     VDAWQWRPDLIWFNNLNIVKTPNYYVQQLYGHNAGTNVLPLTMNKEAVTGQSELFATA
                     ALDKGTNELIIKIVNTGIQSKKIQLNLNGISSGKHKGKLMVLHASDLEAKNTLGKPET
                     VIPIESAVELEAPATEVSVQPLSFLVYRISL"
     gene            complement(42346..43944)
                     /locus_tag="ACZPB4_04025"
     CDS             complement(42346..43944)
                     /locus_tag="ACZPB4_04025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate:alanine exchanger family transporter"
                     /protein_id="HIR1097421.1"
                     /translation="MFETLLQSSYFALFLIIALGFMLGRIQIKGLSLDVSAVIFIALL
                     FGHFGVIIPKELGNMGLVLFIFTIGIQAGPGFFDSFRSKGKTLIILTLLIVGSACLTG
                     ILFKYILDIDTPSIVGLIAGALTSTPGLAVAIDSTQSSAASIAYGIAYPFGVIGVILF
                     VKLLPKMLRKDLIAEAKALEAQRKSQYPTLHTAAFKVTNKNICGKSLAQLQVRAMTGA
                     VVSRIKHDNVISMPTPHTTLNEGDLLKAVGNDKALEQLTLLLGERIEGDLPLSGGQTL
                     QSLLLTNKSIINKSLGHLNLQGTFGCTVTRVRRSGIDLSPEPNLVLKFGDKLMVAGEK
                     ESVNELAQFIGNDEKRLSDTDFFPIAMGIVLGVLFGKLNISFSDSFSFSPGLTGGILM
                     VALVLSAIGKTGPIIWSMSGSANNLLRQLGLLLFLSEVGTSAGVNLVSTFQSSGLTLF
                     GVGIAITMIPMIIAVLAGYYFFKINILDLVGTIAGGMTSTPGLAAADSMTDSPAPSVA
                     YATVYPIAMVFLILFIQMIANLIV"
     gene            44075..44833
                     /gene="truA"
                     /locus_tag="ACZPB4_04030"
     CDS             44075..44833
                     /gene="truA"
                     /locus_tag="ACZPB4_04030"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HIR1097422.1"
                     /translation="MRRYFIYLGYNGKNFRGWQIQPNGMTVQQSIEEALAILMRTPVP
                     IVGAGRTDAGVHAHLMIAHFDWEEPIGDLVFLAEKLNRLLPKDIAVYKIVPVVPEAHA
                     RFDATSRTYKYYVTTKKDPFNHELVYKLPGRLDFEAMNEACKVLFDYIDFTSFSKLHT
                     DVKTNNCHIQHAGWTQEGDIWVFTIRADRFLRNMVRAIVGTLLEVGRGRLTIDGFRNV
                     IEAKDRCKAGTSVPGHALFLVDVTYPEELFPVED"
     gene            44837..45733
                     /locus_tag="ACZPB4_04035"
     CDS             44837..45733
                     /locus_tag="ACZPB4_04035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010802388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HIR1097423.1"
                     /translation="MWLALAFLSAFLLGCYEVNKKMSLNGNAVIPVLFFNTLISSLIF
                     VPFILLSFYTDCLDGTMVYVPRASLEDHLKVLIKAVIVLSSWISGYFALKHLPLTITG
                     PIKASQPVLTLLGAMLLFGERLNLFQWVGVLLSIASFYLLSSSGKKEGIHFAHNKWIF
                     FTVLSILTGAMSGLYDKHLMRSMDVMTVQVWFNVYQCVIMSFILLFLWYPNRKKSTPF
                     QWRWNIIFISVFLCVADWVYFYALTFPDSMISIVSMVRRSNVLVTFLAGAIFFHEKNL
                     KNKAIDLFLVLLGMIFLYLGTK"
     gene            45745..46374
                     /locus_tag="ACZPB4_04040"
     CDS             45745..46374
                     /locus_tag="ACZPB4_04040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3256 family protein"
                     /protein_id="HIR1097424.1"
                     /translation="MRRVIVTLLICVFALGMNAQDMTSVFTAMPDQYIPQLEHAWRKD
                     LVDLYTSGKESRLKNTMNGFSTLQKLTNDYLLLQTTERSTVEMKLLPLVNNTYVVCMI
                     STVNGPVPDSRIEFFTTNWEPLATSDLFTQPTSDWYIKQGIDKKDEAYQEAASHLDMD
                     LIQYRLSPDDQTLTAIYTTPQYLSQEAREKIEPYLIEPKVYTWQKYHFQ"
     gene            complement(46494..47336)
                     /locus_tag="ACZPB4_04045"
     CDS             complement(46494..47336)
                     /locus_tag="ACZPB4_04045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY-like domain-containing protein"
                     /protein_id="HIR1097425.1"
                     /translation="MKTKAFIMATLVCSSFVFMSCDDDDDKFTPESIVTKAFDTKYPD
                     AQRVSWENEAGYVKAEFYTGSYEAEAWFDPQGNWMLTETDLPYNALPQTVKNSFEASL
                     YAKWKIDDVDMLERPDAGTIYVLDVENGEQDADLHYTEGGILIKEVTDGNGDNEHRPS
                     VTPSAIKELISEMYPGATILEIDTETKGTEVDILHENIHKEVWLDTQNKWLYTEWEIR
                     SSQVPDIVMTAFKASAYASYQIDDIHVIQKAEGLSYEFELEQGDRDITILFNEEGILV
                     SPTH"
     gene            complement(47386..47829)
                     /locus_tag="ACZPB4_04050"
     CDS             complement(47386..47829)
                     /locus_tag="ACZPB4_04050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY-like domain-containing protein"
                     /protein_id="HIR1097426.1"
                     /translation="MKRINYLLIVLSLLSVMACAGNDKITSDTNILPVSSRQFISDHF
                     KDIPVSHIQIEKNLIRISSYDVILTDGTNVEFNHKGEWKEIKRHGLPIPPAIIPEVIQ
                     DLIKKNYSSNKVVKIEKEIRDYEIKLDNGLEMTFDLKGNLIDIDD"
     gene            complement(47897..49168)
                     /locus_tag="ACZPB4_04055"
     CDS             complement(47897..49168)
                     /locus_tag="ACZPB4_04055"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1097427.1"
                     /translation="MKLIHYTLRNLFVPILVIFAAWGCVFCLMILHEVEDETNDSLEN
                     YKEIIIRSALADSTLLKDHVDIMTRYYIREVPESEAKLDKDEFYDTTVYIEIEQEYEP
                     VRALRTYFMTKDRKFYELTLELSTLEQEDMIETIIWSMAVLYIALISCILFVIHRGFK
                     RSFKPLYKLLSWLKSFQVGKYNPPLNNPTPIEEFKILNETVQESVNQSDKLYNKQRHF
                     VENAAHELQTPLAVCMNKLELLSEHPDCTEDQLKEIAGLHQALNGIIRLNKSLLLLSR
                     IDNKQFPETRDICLNHLIHKILEGINDIYERKALHLRVSEKESLVCTMNESLATTLIT
                     NLIKNAYVHNYEKGDIGITISRRMLTIANTGIDKTLDKELLFARFASQSKQQESTGLG
                     LAIVKSIVDLYSIRIDYQYANGMHTFTLLFY"
     gene            complement(49171..49851)
                     /locus_tag="ACZPB4_04060"
     CDS             complement(49171..49851)
                     /locus_tag="ACZPB4_04060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HIR1097428.1"
                     /translation="MKILVVEDENALREVIVRSLEKERYVVESASSFREASLKINDYD
                     YDCIVLDIMLPGGSGLTLLKELRALRKKDSIIIISAKDSIEDKVTGLDLGADDYLTKP
                     FHLAELNARIKSVIRRKQQDGELQLSLANLTIYPDKHSVYINGKEIVLNRKEFDLLYY
                     FISNPNRLISKATLAESVWGDYIDQADNFDFIYSQVKNLRKKLKAAGAIPEIKAVYGF
                     GYKMTDEE"
     gene            complement(49929..50381)
                     /locus_tag="ACZPB4_04065"
     CDS             complement(49929..50381)
                     /locus_tag="ACZPB4_04065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY-like domain-containing protein"
                     /protein_id="HIR1097429.1"
                     /translation="MKLKVSFTAILFMSSCLFLTVGCQQKKQGFDDKSVSQAIQKVIQ
                     IKYPGATITDYDKDAAGVEVDIKDKGVKKEVLLGKNNEWLSTKFDIHAEDVPVDIMDN
                     LTNSAYHEYKIDEVTQIDKPSGTFYVFKLEHENNEVRLTFNSEAQLLK"
     gene            50451..51002
                     /locus_tag="ACZPB4_04070"
     CDS             50451..51002
                     /locus_tag="ACZPB4_04070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HIR1097430.1"
                     /translation="MICFSSFVVLIIEMELETFKITVLPLRQKMLNFSRRLVEDAADA
                     EDVVQEAFIKLWYIREKLDAYHSVEALAMQVTKNLSLDKIKLRKPQGSELESVTLISE
                     AVSPDEQLEQKDAAECIRRLIAQLPTLQQTIIRMKDIEGYELAEIAEITATPVENVRV
                     NLSRARKKIREQFLQLNKQEKWT"
     gene            50993..51538
                     /locus_tag="ACZPB4_04075"
     CDS             50993..51538
                     /locus_tag="ACZPB4_04075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097431.1"
                     /translation="MDIDELLNRYFEGETSSEEERELRAFFTSGNVPDRLAVYTPMFT
                     YLEEESRKERQPDEALIPIDEDILFMLDAEKVEEKKTFTLRSVLYLVSGIAASFLLLL
                     GLNHLLNPVDPCFCSDNYVVINGRCYTDIHKVRSMALEALQEVATPTDEYFPEVDLDE
                     ADRVIIDNQLDELRSLFDDNE"
     gene            51552..52016
                     /locus_tag="ACZPB4_04080"
     CDS             51552..52016
                     /locus_tag="ACZPB4_04080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097432.1"
                     /translation="MRRFKYMLWLLVAVFCLMPCGVSAAETQKDLKIQEVFQRYGKKR
                     NVTMVELSNEMLETYGMTRYKSITIKDDPEALRFTRQCLEADQKGARKIKEVTDDGGV
                     VSAYYQLKGVEADINRFVLFKVSKKGVITLVYIEGDLDSDDLITLLFTKKDL"
     gene            52038..>52762
                     /locus_tag="ACZPB4_04085"
     CDS             52038..>52762
                     /locus_tag="ACZPB4_04085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane beta-barrel protein"
                     /protein_id="HIR1097433.1"
                     /translation="MKRILLVLMACFPVIGLMAAEVEPLAGDTIITLERKRIEVKDNG
                     DRMKVRVYEVDEDGDSVDDELIFEGHYRDGQSYERRKHVKSINIPVPTWDKDFNPHWA
                     GFGMGFANFADGSLHVNDVDGVSLRSGNSLEYNLNVLEKAFPFSRYRWAVVIGAGMRW
                     SRYRIDTNEYFKEIDGVTALRPAPESVTLKASKLNITSLTIPLLLEWQPKKRSSEFFL
                     SAGVVGVIKTCSSSKIVYNDASG"
BASE COUNT        12693 a        11667 c        13670 g        14632 t
ORIGIN      
        1 tccagctcgt aacctaggct gttctgttgg atatccagca actcggcgtt ggcgaaagtg
       61 atctccatca ggttgctgac ctctttcggg ataacgatcg gtgcgtcatt attgatctca
      121 tcgtccacga ctttgatcag gtttccatac tgtgaataat acaggtctac ttcgctattg
      181 gactgctccg cctcgatttt gtaaacgatt cccatattca ggcgattgat ggcatacgta
      241 tcatccacgg tccaatttga gtaaaagcct tgtttaaagg cggtggatac cgctgccggt
      301 aattgggcga aagagatgtc tatcttctcc atcatccata cgccttgatc cgtgaaccaa
      361 gcggttgtct cggaaccttc attattgaaa tctaccacat aatagttacc ttcgatctca
      421 aaaacagggt tcttggcatc gggatatttc tcttgaaaag cgttctctac cggtggaaga
      481 gggataatac cttgatgatc atcatcattt ttgctacagc cagagaaaaa gagagtcaga
      541 ccggctatac aggtgaatag aattagtctt gtgttcatac attttgcgtt tataagtttt
      601 gggcatagaa caacaggtct atcggaaaag ttttgagcga aatcgattta agtatattga
      661 atcaagaaca aggatcttgt ttcgacgaga tccttgttct tgtataattg ctacggattt
      721 acgttcaaat aataggttgc tgtgcctatt aaagaacttc cattatacat tgcgcaggtg
      781 atgcgaagag atccaccgta atgttgggag tttagataga cactaacatc taatcgatta
      841 ccggaaggat aagtgtacca tctatcgcat tctccataga attcagcgtt ccagctatac
      901 gaggtcggag ttcctgtctt tgtgtaagca tataaagtcg tcgtggcatt accccctggc
      961 gcattgatag aggaactgcc gctactataa tcctcttgac tcttccctat ataaacagtc
     1021 ggcatatcat tttttttcat atattttaag cttgatgcat caaagggaca atgagctttg
     1081 ggatgcctca taagagcgta ttccccccat ttggagatga atatattggg cgtagatgtc
     1141 gttacggcag agtgattatc actaagatag gatactttgg ttgcggcacc tgttgttgat
     1201 atataactac catctaacca atatacgttt gtgggattaa tagtccatcc catccaaact
     1261 gctgatccgc cttcagtcat ataccaagca taggcatgac aattgtaagt ggttgttgaa
     1321 ctacttatta gagttgcttg tgaataggtt gttgtacaat attggtcatg gctcgctttt
     1381 tgtgaggctg ataattcctc acttctgtag taagtgtcat taacgagtgt cccgttagga
     1441 gtgtaaacag tagcggctgc tccttgagct tttgtctcaa cattgagatt cggctcccaa
     1501 atcatgttta aattctccat agtgatccat tcattgggga atttttcgat tcgttctccg
     1561 gaaagcaaga atagtaattg cccgcaagaa gcacaagaat tcaccccatc caaaacgaga
     1621 atgtgttctt ttccatctcc ttgaatagta aagacccaag ggtatggata gtctgttccc
     1681 ttgacatggg agtgagcgac agaatctact acattcacca accatttagg atatgttatc
     1741 tttccgtctt taatgacaat ttctgaactg gatgtcaaga tttctttatc acctccttgc
     1801 atattatcca tttcattgtc acatgcgttc agcgtgaatg ccagcatgat tattaaatag
     1861 tataatactt ttttcatgat ctcaatttat taaaggttac aatgtattgt tttaataact
     1921 cttcgattac attactgccc gttagctttt catcgatggt gaattgttta aatttgggcg
     1981 taatggtctt gttgtctatc cgttctagac ttcgacctag gagatagact acggttttta
     2041 gaccatattg tccataaata tccgggttgt tttgtttgta aaggagtctc tttacggctt
     2101 cggaggagat ctcttgctgt aaaagattat ttgtattaga taatatcgtc tcattagaca
     2161 gaagagcctc gattaccatt tgccgactaa tttcattacc tatttctatg gaagtcaaca
     2221 ctcctgcttt cagtaattct tgttttttca tcttctcaaa tagcaaagaa gcattgtctt
     2281 tccttttgaa taactcttgt aacccgttaa aacgtgcgga aaccttgcta atgccttcct
     2341 gtattccatt gtaagcgaat atgtcgccta ataatgggta agcaaggcaa agttctataa
     2401 gctcttctgt tgataccgtt tttaatatct ctgccggaat ttggcaggct ttcagcatat
     2461 cctcatgtgt ggataatgct tgccaagcct ccgttcctgg ttttatgggg taatcccaac
     2521 tttttattga ttgtgcgttc atatctatcg atataaacac gaggaggaaa atgctccaaa
     2581 cgaaagttac tgtttttttc atctctcttt agaatttagg gtaaataata taagattggt
     2641 attccttgat tatggatttt cccaaaaata gtcctttttg taaagataat caagtattta
     2701 tatgttaatt atgattgaat atctgtagat tctcattgct gatgtctttg ttttcgtaca
     2761 aaagcggaca cagtgttcga tatcggacat ctcttttgtt ttatttcttc aataaatcaa
     2821 tcacttacgt ttttggcacg gggtttgctc tttggagggt ggaaaataaa aacaaacgaa
     2881 atatggacag agagatatca aaagaggttc ggcagaagga gcagcgtaaa cagtttataa
     2941 agctgggggc ggggattggt attgccgttg tcttaatagg cggggtgatc ggtttcatgc
     3001 aaaccagcct gcaacggaag gacttggttt tttcaacggt agataaagga gtgatcgagg
     3061 tttccgttag tgcgtcaggc aaggtggttc ctgctttcga ggaaatcatc aactcaccga
     3121 tcaactcccg tatcgtcgag atttataaaa agggaggcga ttccgtggat gtaggtactc
     3181 cgatcttgaa actggacttg ctcagcgccg agacggatta taagaaacaa ttggacgagg
     3241 agcaaatgaa acgcctccaa ttggatcaac tccgtatcca aaaccgcaat aagctttccg
     3301 agatggagat gcaattgaaa gtctctcgca tggaactgaa ccgaaaggaa gtggagttgc
     3361 gcaacgagcg ttatctggat agcctaggcg ccggaacgac cgataaggtc cgtcaagtgg
     3421 aactggacta taacgttagc gtcttgaaac tgaaagagga tgagcaaaaa tatgagaacg
     3481 agaaatcctt gacggatgcc gattataaag tgaaagaact cgacctgaac atcttccgaa
     3541 agagcctagc cgagacgaag cgtaccttgg aagacgccca gatacgctct ccccgcaagg
     3601 cgatcctgac ctacgtgaac aacgaggtag gtgcccaagt ctctcaaggc agtcgtgtcg
     3661 ctatcgtctc cgacttgtcc catttcaaga tagaggggga gatcgccgat acctatggtg
     3721 accggatcgc cgccggtagc aaagccgtcg taaagatcgg caacgataaa ctggatgggg
     3781 tggttagcga tgttaccccc ttatcgaaga acggcgtaat ctctttcacg gtacagttgg
     3841 aggaggataa tcatcgccgc ttgcgctccg gtttgaagat cgatgtatac gtgatgaatg
     3901 ccatcaagga cgatgtgctg cgtatttcca acgcctcgtt ctacgtcggg aaaggagagt
     3961 atgagttgtt tgttgtcaac ggagaccaat tgatcaagcg gaaggtacag ctgggagaca
     4021 gcaactttga gtatgtagaa gtagtaggtg gcttggaacc gggtgacgag gtggtcgttt
     4081 ccgatatgac aagcttcaag gagaagaaca aactgaaatt gaaataacga ttcgaattat
     4141 gtataagcag tacatcaaac aagcggttct aatgctgcgt gaaaatatgc tcgtaagcgt
     4201 aatctctatt tcgggaacgg cccttgcgat cgccatggtg ttggtgatgg tattggtgtt
     4261 ccagattaaa tccacgggat atgcccctga gtccaatcgg tctaggttta tgtatgtctg
     4321 gggtacggaa gtcggttcga aatcccccgg aggatcggat cgtaatcgtg gaggcatgtc
     4381 cagcgaggtc gtgaaggaat gtttctatac cttgcggaaa ccagaggccg tatccggcta
     4441 ttgtagtgat agccattcct tgtcattgcc caatagacgg ctcttcaagg agtatgagat
     4501 ttgttatacg gacgcgggcc attggaaaat attcgaccat cctttcgtgg aaggaggccc
     4561 ctttagcgag gctgattttc aatccggtat accgaagatg gtgctgtcgg aacaggtggc
     4621 gaccgatttg ttcggaacag gacaggccgt cgggcggcag gttgtgatgg attttatcac
     4681 tttcaccgtc tgcggggtgg tgcgtgacgt accttcttca ttgatgagct cctacgctca
     4741 ggtatggata ccctatagca gcaatgaggc cctgacccgt gtaaatgggg agtatgggga
     4801 gaatatggcc ggttatttca gcgtggcctt attggctcgt tcctcttccg acttcgatgc
     4861 catacgctcg gaactagacc aacaggtccg tcgctacaat gacagcaaga ccgattataa
     4921 cgtaggtttc ccttccgggc tactttccca gttggatacg gccatgggaa gcggcgcttt
     4981 tcaaaaggtg gactggccta ccttcttggc cggatcgggc actttccttt tcttcttgct
     5041 cttggtcccg gcgctgaact taacgggcgt gatccaatcg tccgtccaga agcggaaaga
     5101 agagatcggt ttgcgtaagg ctttcggggc tacgggacag aatcttttga tgcagatctt
     5161 atcggagaac tttgtgctga ccttgatcgg cggcgtgatc ggcattggcc tctcgatggt
     5221 cttgttggtg gtagggaagc ctttcatgtt gagcgagaac gtgagcctta cggcgcctat
     5281 gcttattaaa ccgggcttat ttatctccgc ccttatcttt acgttcttgc tgaatatatt
     5341 aagcgccggg ataccggcat ggcgtacgac aaggcaaccg atcgtagaag cgttaaaggg
     5401 gaacgagtga atccaatgaa tgatgaacaa tgagttgtca attgtcaact atcaactatc
     5461 aaattatgat taagcatata tttaaaataa tatgggccca gcgcaagagc aacggctgga
     5521 tactgggcga gttggttatc gtgatgtgcg ccctttggtt tatgatggat aagttatggg
     5581 tggatgtgcg ctgctataac gccccgatgg gatatgatat ctcgaatacg tggcgtttca
     5641 agctttccac gctctcgtcg aacgccccgg gttatgtgcc cgactcactt tacgactcga
     5701 acgcaacaca ggatttgttg aagcttatgg aacgtatccg ccaagagcag gaggtcgagg
     5761 aggtatgtgt tacgtattgg tccatgcctt attcaaacgg aagttcgtgg gggacgcttc
     5821 ttcccttggg cgctgatacc tcgaaggcgg taggacagaa ctaccacaag ctgaaagtat
     5881 ccccttctta tttcgatgta ttccgtatga aggataagga gggccgtgcc atcaccccgc
     5941 tggtggagaa cgcttaccgc ccgctcgtca taacggcgga ggcggaggat ttcttcttcg
     6001 gggggcagtc cgccataggc cggcagatct cggagaatga cgacctttcc gagcctttca
     6061 cgatcgccgc tgtccttcct accttccgta gcaatgactt cgaccgcccg gagaactgcg
     6121 ctttcacgat attgaaaggt gagtcattgc aggagttcgt gaagaatttc ggcgtaagga
     6181 gcgctgaact atcggtacgt acgaaacgcc cgatgaccga ggatgagatg tacgctttct
     6241 tggagaaaac agcggatcgg atgacggtaa ataacacctt cgtccacggt gtcaccctcc
     6301 ttgccgacca gcgtgatgac caactccggt ttaccaagaa cgagaacagc aagaaactct
     6361 ccatgatggc cttcctgctc gtgaacgtat tcttcggtat cgtaggcacg ttctggttgc
     6421 gtaccgagcg gcggcgtagc gagatcggtc tccgcatggc gatcggttcc agccggggca
     6481 ggctgggcga gtacatgtat ctggaaggtc tgggcctctt ggcgatcacc gtgccgatcc
     6541 tactggtctt cgtcttcaat atggcctttt tggataagct ggattcctac cgcgagcccc
     6601 tctccatcct ccgctttcta gtaaccctca gcgtctctta cctcctgatg gccggcatga
     6661 tctgcatggg aatctggttc cctgtccgca aggcggtaaa gatggctccg gcggaggcgt
     6721 tgcattacga ataaattgtt tatctttgcg tctgtcaatt tattaatgag aaaggagcaa
     6781 gcgtatgaca gctatagaat taaaaatgtc gttattgcaa gaggtgatgt ctttggagga
     6841 tgaacagttg atcaagaagg ccctcgacag tgtccgccgt atgaagatgg ctgccttcgg
     6901 taaggccacc ccggtagaga agccggcaga cgattacgcg gagcctacca aggaggagat
     6961 cttggcgggg ctaaggaatg ccctgcaaga cgtgaaggat ttgcgtgagg gcaaggatgt
     7021 ggggcataag tttagagact tgagtgagtt gctcaatgag gtataggata aaaacccatc
     7081 aagacttcga taaagagttc aaacgtctct gtaagaagta tagctcattg aaggctgatt
     7141 tatcggcttt gggtaagtct ttgagcgaga accctgatca agggacgagc ttaggcaaag
     7201 gcgttcgcaa ggtacgcatg gccatcgtct ccaaaggaaa aggaaagagc catggggcga
     7261 gagtgattac ttacacggag gccattgtct gcgcagataa tgagggtacg gttattctcc
     7321 tcacgatcta cgataaggcc gaccgtgact ccatttcggc agccgagatc gatgaactgc
     7381 tgagatcctt acgttgggaa ttataaaatc tgaaactgtc cataatcgct gtccgataac
     7441 gaatcaagtg ttcgttatcg gacagctttt tttacggggt gatgttagga atcaagtggt
     7501 tacgtttttg gcacgttatt tgcctccgta ggggcacaaa gtcggatgat aacaaacaat
     7561 cgctgtttta gtcgggtaat agataattta taatacaaaa gtttatgata aagcaataca
     7621 ttaaacaagc gttgaggatg atcggggaga acaagctgtt gagcgtgatc tcgatactcg
     7681 gtaccgcctt ggccatttgc atgatcatgg tgatcgtcat cctgtatgtc gtgaatacgg
     7741 cgagtttcaa gccggaggta aaccgtggcc gcacctgcta cataacgacc gtcatgagca
     7801 atggcaagga tgataaccgg cgcatctcct actcgtcgtt gggactgccc ttggtgaagg
     7861 aatgctgcta tccgctgaaa ggggcggagg ccgttaccgc catcaacatg gatcgctata
     7921 ggccgttgac cgcctcgtcc atggacgggc ttaagaatcg gacgagttac atctcttata
     7981 cggataccgc cttctggaag atcttccagt tcgatttcca gcaaggaggc cccttcagcc
     8041 cggcggcttt cacgagcggt atccgcgacg ccgtgatcag cgagagcgtg gccttggccc
     8101 ttttcggcac ggaccaagtc gtggggcggg agatgaagct cgatttcatc gtctacaata
     8161 tctgcggggt cgtgaaggac gtatcccggt tcgcctcgaa agcgtgggcg gaggtctgga
     8221 tcccttacac ggtgcgggac gacgggggat accaagaggg catcaacggc tcgtatagct
     8281 gttgcgtcct gctgagaccg ggcgtcacga gagaggagtt gaggaccgag gcgctgcgga
     8341 aggtcgagga gttcaacgcc aagacccggg atgtcaaggc cgatatcctt caccagccct
     8401 ccacccagat cgaggaatgg atcggcggcg gtagcgagtt cggggcgaac ctcttctacc
     8461 tctacgttcg ttacggtatc atccttttca tcctcctgct ggttccggcc ttgaacctat
     8521 cgggcatcac cctgtcgagg atgcgccgcc ggatggccga gcttggcgta cgccgggctt
     8581 tcggggccac gcaaggcacc atcctctggc aagtgctgtc cgagaacatg gtcttgaccc
     8641 tgctcggcgg actgctggga ttggcgatgt cgtacggcgc catgttgttg ctgagggact
     8701 ggttgctggt cacctcgctg gggaagacgg ggctttccac cgggatgttt aacggggcgg
     8761 tctttatcgc cgccttcctg ttctgcctcg tgctgaacct gttttccgcc ggcctcccgg
     8821 cttggcgaat gtcaagattg aatattacgg actctataaa tggttgacgc tatgtataag
     8881 atgattctaa aacaactctg gaacgagcgc aaggggaact tgtttatctg gttggaaatg
     8941 ctcgtggtct ctatcttcct gtggtacgcg gcggacgcct tgttcgtgat gtacagactc
     9001 tactcgcagc ccttgggctt taacatcgag catacgtatc atgtgagttt cggcgtgatc
     9061 ccggaggaaa gccccgatta tgacacgacc tccgtgcata gcgagcgggg aggcggggat
     9121 tacctgacct tgatggaccg catccgccgg aacccctccg tggaatcaat ctgtttcacc
     9181 accggcgtgc attttcatta ccggggatcg aaccaatacg ccacgttccg gaaggactcg
     9241 ttgatccgta atggcttcgt gcgcttcgtc tcgcccacct atttcgaggt gttcggcgtg
     9301 aagacggcag aaggcggttc cccctcggag ttggtggacg ccctgcgcga caaccaagtg
     9361 gtggtgacgg gccgtgtagc cgatgacttc ttcggcaacc cggcggcggc tgtgcgccaa
     9421 gagatctata tcaccaacca aggctctcgt gatagcgtgg cctaccgtat cggtggtgtc
     9481 tgcgagaaac aacgttactg cgagttcacc ggctatgatt acgcctacta taagctggtg
     9541 gacgagaaca aggtggccga ggagggcgat tgggtcggag agggcctgaa caccttcatc
     9601 cgggtgaagc ccggcgcgga cggcgccgct ttcgccacca acttccggaa ggagatggag
     9661 cagcaattgc gcgtgggcaa tatctatctg aaggatgttt tcccgatgtc ccattaccgg
     9721 gaccagttcc ttgagcgttg gttggatcaa gtccgccttt acgtggcggg catcgccttc
     9781 ttcctgctga atgtcctgct cggcgtggtg ggaaccttct ggtatcgtac gcaacaaagg
     9841 agcgccgaga tcggcctccg catggcgatg ggagccaccc gcaagggcat attctggcaa
     9901 ttggtgaagg agggcttggc tctactcacc atcgctttca tcccctctac cgtcatcttc
     9961 gccaacctgc tgcatatgga ggtgacgcaa ggctcggaga taccgcccga catggcctca
    10021 cgcctgttgt tcggtttcgt cttctcgtat gcggtgatgg ctgcgatgat tgtcgtggga
    10081 atcagttttc cgtcttaccg ggccatgcgg atgcatccgg cggacgcctt gcggcaggaa
    10141 tgatcagaca cggacatctg tgttcgggaa tgaaccgact gttcgataat ggacagtgct
    10201 ttttcaggaa gatgccatgg aatcaatgag atacgtttct ggcacgtaat ttgcttttag
    10261 gtggcaaagc ctannnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    10321 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnaaccgac
    10381 tgttcgataa tggacagtgc tttttcagga agatgccatg gaatcaatga gatacgtttc
    10441 tggcacgtaa tttgctttta ggtggcaaag cctagcgata gcaagagttt aacaataaca
    10501 agagtcaaac aataacaatt aaaatattac agtcatgatc aaactaacga atttacagaa
    10561 gatttaccgt acgaaagaga tagagacagt cgcgttggaa aacgtgaacc tagaggtgca
    10621 gcaaggcgag ttccttagca ttatggggcc ttccggatgc gggaagtcca ccttattgaa
    10681 catcatgggc ctgctggacc ttcctacctc cggcacggtc gagatcaacg gcgtaaacac
    10741 ggtaggcatg agcgacaagg agttggccgc tttccgtaac aagcagttgg gtttcgtctt
    10801 ccagagcttc cacctgatca attccctgaa cgtgctggac aacgtggagc tgccccttct
    10861 ctaccgcaag gtatcctcct cggagcgccg caagctggcc gaggccgtgc tagagaaggt
    10921 cggcctgagc caccgtatgc gccatttccc gacgcagctc tccggcggtc aatgccagcg
    10981 tgtggccatc gcccgtgcga tcgtaggtaa ccccgacatc atcctcgccg atgagccgac
    11041 cggtaacttg gactccaaga tgggtatcga ggtcatggac ctgctccacc aactcaacaa
    11101 ggaggacggc cgcaccatcg taatggtaac ccacaacgag gcgcaagcca agcaaaccag
    11161 ccgcaccgtg cgcttcttcg acggaaggca ggtgcagtaa ggggcggatc taggacacta
    11221 ctgctcgcat cactcatgat agctatcatg cgttaatcat gaaagctatc atgaatcgtt
    11281 catgaaagtt atcatgtgtc gctcatgaaa gctgtcatgt gtgatacgag cagggaaggc
    11341 tcgggagcta tctcactagg aaggtgagtg ttccatagcg gggttgcttg tatggacgcg
    11401 agttgggtgt gtattgcgtc accacctccg ccacccactc gccgtcggtg aaagcgaagc
    11461 cgggcgtgaa gcaaagtcgt ttgccggtat tgataaacac ctcggagggc gggtagaagt
    11521 gttcttccga gccgtcgggg cggtgcaggt agagacccac gcggggatcg tcgcccatca
    11581 gtttcagccg gtcgccatag atggagatga agtggtgctc acctgccgga agctggttgt
    11641 aaggctcgtc gcagtcgggc gtgcgaggct ggatgcggag gctgacgtaa gcgggacggg
    11701 gctgggagtt gtaatccagt tggtaggtct cgttcacggc acgcaagttt gccacccgtt
    11761 gtttcagctc cggcgcgggg cgcaggcgtg gggcgagcgt atggcggttg gggtcgaact
    11821 tctcgtacag gctctcgaaa ggcccgttca cggtcagttc cgtccgcccg aagccgaagt
    11881 ccacgttgta gccctcctcg atggcgtcgt agatctcccg cttgaggagg ttgaaggtgg
    11941 tgatgagcgt ctccttgcga tactcgctcc gtttgtctac gacacgggcg gcgatgtcat
    12001 cgatgctgag cgtacgttgc catacgacgc ttcccttgta gctcgcgtta ccgggcaggt
    12061 ggctcttgct gacgcggagg ctcagcttgc gaaacggctt gggcagctcc gacttaggta
    12121 attctttatc catgatctcg tggtttaatg aatgattaag tggcaaagat aagaaagata
    12181 acgtgaatcg aatgagtatg tacaagatct acataaagca agcatgggcc ttgatccggc
    12241 aggagcgctt cttcagctcg gtctacatcg taggcacggg gctggccatc tctatggtaa
    12301 tggcgctggc ggtggcctac catatacgta cggcgaatat cgctcccgag gtgcatcggg
    12361 accggatgtg ctacctctcg aacgtgacat acaagttgaa tggcacgaag agcaattaca
    12421 aggcggcttg cggccctcgc ctcgtcaagg aggtgatcgg taatctccgc gtcccggagg
    12481 acgtggcggt gaccaccaac tccttcatga tgcctttctc ttatggtgac gctttcatgc
    12541 gactgcccgg tggagacgag tctcccaagg tgaggttgaa aggctgcgac gacggcttct
    12601 ggcgtgtcta ccgcttcgat ttcgtggagg ggcggccctt caccgaggcc gagttcctct
    12661 ccggcatgcc ccgtgcggtg ctgtgccgct cgttggccgg ccggctgttt gggcacgagg
    12721 cggcggcggg gcagacgatc ttgctgaacg gcttggagta taccgtgagc ggtgttgtgg
    12781 acgacgtctc cggcataacc gccgatgtct acgccgaggc gtgggtcact tattcctccc
    12841 tctccgtcgc catggaccat gccttgggcg agcgtgacgg ggccgtcggc ctgctggagg
    12901 caaatatcct gcttgccgac gcgtccgacc tgccggctct ctcggaggaa ctgcggcggg
    12961 aggtgaggcg ctataatagc gggctgtccg aagggcaggt ggtatgcgag gagcccttga
    13021 gctatgccga caatctcctt tccggattgt tcggccccga gacctacatc gtgcttggga
    13081 tggcgctcct ccttttcttg ttggtaccgg cgctgaacct ttccgggatg aacgcgtcga
    13141 gaatacaaga gcgtgtcggc gagctgggta tccgcaaggc gttcggggcg acgaaggcta
    13201 cgctgatggg gcaggtcttc gtggagaata tggtgctgat gctgcccggg ggcgtggcgg
    13261 ggctgctctt ctcctacgtg ctggtgttca tcttccgtaa cgccctcctc gtgcctgggt
    13321 tcaatcttct ggggacgagc ggggatgtct tcctctcgcc ggggatgctg ctcaatatgt
    13381 cggtcttcgc gtacgccttc ggggtttgcg tcgcattgaa cctgctttcc tcgatgctgc
    13441 ccgcttggag gatcgtgagg gggaatataa cggatgcgtt gaatggataa ataggagata
    13501 cggttatgat aatacatata ttgaaactga taaggtcccg catggggggc agcggatgga
    13561 tactggccga gttgctggtg gtgttcgtgg tgatctggtt catgaccagc tacttcttga
    13621 tgatgggtaa gtcgtggtat gagccggtgg gctacgacct cgagggcgtc taccatgcgg
    13681 tattggccgt ccgtccctcc aacagtccct cgttcgttac ctacgaggag ggcggcgatg
    13741 aggctgcgcg cgacgtggag cgtatcgtgg aacgcctccg ggggcatgcc gacgtggagg
    13801 ccgtggcgct ctccgtctct tccttgccct ataccctttc ttggtcggga agccgggtga
    13861 cgagggattc cgtcagcgta agcgtacggc tgatgaccgt ctcgccggac tacttccgtg
    13921 tgtttggcat ccgtcccgcc tcgggcgaaa gcccggagag gctgggcgag gctctgtccg
    13981 ggacaaggga aggcagggat cgggtgatat cggcggagtt ggcgaggcgg ctatatggca
    14041 cgaccgacgc tatcggggcc gatatctacc tgcatggtga tacccttccc ggacacgtgg
    14101 tggcggtgac agggccggtc cgcaatgacg agttcgaccg ccggaagcaa tgtatcctct
    14161 tctccttgct cgacctgcgg gagcttaacg atcttacaca ggtgcagata accttccgcc
    14221 ttcgcccttc cgtggctacg gccggttacg ccgatcggtt cctgaaagcg atgaagcgtc
    14281 aattgatggt gggcaacttc tgggtgtcgg aggtgcgagc ctaccccgac gtgcgatcct
    14341 cttatctgga gaactcgatc gagagtaacg cccagcggat cgtctccgct ctgggcctgt
    14401 tcctgctcac gaacgtgttc ctcgcggtga tcggcacgtt ctggtttcac gtgagccgcc
    14461 gccgtgcgga gctgggcttg cgtatggcga tgggttccac gcgtgcctcc atcttgggct
    14521 tggtgatggg ggagggcttg atgttgctga cgatcgccac cgtcccggcc ctgttgattt
    14581 gcgtgaatct agcctggatt gacttgatgc cgcccggctt ggtagaatcc aaggtaggct
    14641 gcttcctgat caactccctg ctgacttggc tgatcttggc gctcatcatc agccttgcca
    14701 cttggtatcc ggcccgcaaa gcctccagct tggaacccgc cgatgccctg cgctatgacg
    14761 gataacagat aacacccggt tgtagagacg gggcgtgccc cgtctctcac cgactgatag
    14821 aatatttaaa tggaatgaat atgtataaga tctacttaaa acaagcatgg gccctgatcc
    14881 ggcaagaacg gctgttcagc tcggtctata tcgtggggac gggattggcg atctcgctgg
    14941 tgatggtgct gtccatcgtg ttttacgtga aaatggcctc tatttatccg gagatggacc
    15001 ggaaccggtt gctgaccgtg aagagcgctg cgctgaagaa tgagaaaggg ggcacgagca
    15061 gtggcccggt atcgccccgc ttcgtggaag agtgccttgc gggggtgccc ggcttggagg
    15121 cgttggcgct atgttgcgat gacgccgcct ccgctttcgt gcagccggtg ggcagtcccg
    15181 tgcagatacc ggtcatgaag atgggggtaa acgatgggtt ctggaaagta ttctccttcc
    15241 gtttcctgga gggcaagcct ttcaccgagg ccgatttccg gtcggggatg cccgtggcgg
    15301 taatcgcccg ctcactggcc aagaggcttt atggagaagg tagtgccgtg gggcagacct
    15361 tgagcctcga ctttacctca tttcgtgtgg tgggcgtggt ggatgacgta tcttacctga
    15421 tggatcgggt tttctcgcag gtctggtacc catataccca agtgcccgac ttcgaggagc
    15481 gggtccgata ctcggaggcg cgtatgcccg ggctaggccc cttgaaggtc tatatgctcg
    15541 tgaaggacaa ggccgatatc ggcaaggtgc gggaggcggt ggcggataac gtgcgtcgct
    15601 tcaaccaatc gttgaacgtg gatggcaaac gtgagttctc ccttcttggg cagccggatc
    15661 gccattggga gagtatcttc cggtattggt cgaacgtgga gccggatatc gtgggagact
    15721 tgagccgtta tggggtgatt ttcctgctcc tgctgctcgt ccccgccgtc agcctctcgg
    15781 gcatggccga ttcccgtatg gagcggcgtc tgggcgagct gggcgtgcgg cgtgctttcg
    15841 gggctcccaa gggggcgttg atcgggcagg tcttgatgga gaacttcctg tatacgctgc
    15901 tgggcggctt ggtgggactc ctgttctcct tcctgttggt gacgttcgcc agttcgtggg
    15961 tcttcaagat cggcaacggc ttctcggatg ccgccccgga tggcgtggac gtatcgctct
    16021 ccatggggat gttgttcaac ccgtgggtct tcttgatcgc cttgtgcgta tgtttcctgt
    16081 taaacctgat gtcggcgttg tggcccgctt ggcgtgcgtc aaggcgacct atcgttgatt
    16141 cgttgaacgc ttaaatggag ggaagaaaga tatgtggaaa ataacttgga tacaattgat
    16201 gaaccgctgg cgtagcaacg tgtgggtgtg cgtggagttg ctgctcgcct tttgcctggc
    16261 gtggtacatg gcggattact tcttcgtgga gatctataac cgtagcctcc cctccggacg
    16321 cggctacgcc gatgtctggc aggtagagat gggcctcttg ccggaaacct cccccgacta
    16381 tcgagtcgcc gagagcgact cgatcgccat gctgggaaat tatgagcgga taaaagaccg
    16441 cttgtgcgat tatccgggag tgcaggcgat gggcgcggcc tcggagtgtt actccacgcc
    16501 ttatacgggc tgttattacg gtattggttt ggcgaacgcg gccgatacga gtaagcggga
    16561 agcggtcatg aggtatgaga tagatcctac cacggatttc ctgtcggtct tcaaccattc
    16621 gtacgccaaa gacggccgtc cggtatctac atccgatttt gattggggag acccccgcgc
    16681 tatagtaacc acccggatgg tggagcgaaa ggtatttgga gaggcatccg ccgttgggcg
    16741 tgaggtgaaa gaccctttcg acgaggaggg cccgacttat atcgtaaagg gtgtcttaga
    16801 ggatatcaag cgttttgaca atagcctacc ccaaggtgcc gccttcttgg cgatccgtcc
    16861 ctcggcggag gagatccccg agatgaatta tttcatacgg atcgatcctg ccgtggcagg
    16921 ccctcgtttc gccgatacgt tccgggagaa gatgagccgt gagcttcggg tggggaactt
    16981 ctacctgaaa cgcctgacct cctatgaacg gatcaaggcc gataccgatt attcctttgg
    17041 cgttacctac gattaccggg tccgtatggc gttgatggcc ttcttgggct tgaatatcct
    17101 gctttgcgtg atgggtacgt tctggtaccg ggtgcggatg cgccggggag agatcgggtt
    17161 gcgcatggcg atcggttcgc cccgtgaaga gatacgtagc cagatggctc gtgagggcat
    17221 atgcctgtta ctcatggcta ccccgctcgc cttgttgata gaggcccaat tcgtgatggt
    17281 cggcttcttg gacatcccca aagggacctt gccggagctt tactggccgg cgatcctgcc
    17341 gctccgtttc ttgctggtga atatcctgac atggatactg ctggctatcg tcatcctgct
    17401 cgccgtctgg cttcccgcca gcaaggccgc cgagatggag ccggccgagg cgctgcggta
    17461 tgacggataa cagataatgc cccgtctccc accgactgaa tcgtataatt aaatcaaatg
    17521 aatatgtaca agatctatct aaaacaagcc tgggccttat tgaaagagaa caagctcctt
    17581 tccggagtct ctattttcgg tacggccttg gcgatttgca tgatcatggt gatcgtgatc
    17641 gtatggcaga tacgtaccgc caattactca ccggaagact atcgggaccg gatgatgtac
    17701 gtcagtgata cccgtgcctc ctacaaagag aacgaatctt ataacgactg ctaccttctt
    17761 gcttcccggg tggtaaaaga ttgtttctat cccttgcgct ctgccgagaa ggtgggcatg
    17821 gcctatcatg gcgtgcaacg cttggcggca gtggcggatc atacggtgga gttcaagtgc
    17881 gacgtgacct ttacggacgc ggcgttctgg aatatcttca actttcgctt cctctccggt
    17941 aagccttatg gcgaggaaga agtgcaaagt ggcatcatgg atgctgtggt aagcgagtcc
    18001 gtggcacgtc ggctctatgg cacgactgag gtcgtaggcc gtacggtcga gatcagctac
    18061 gtgccctata ccatccgtgc cgtcgtgcgg gatgtctccc tgctggccga gtctgcctat
    18121 ggcgatgtct ggctgcctta taccacggac aattctttgt atgatgatag ttccgaccgt
    18181 ctcatcgggg gtttccgttg ttatatcctt gctagttcgt ccgccgactt tggcgcgatc
    18241 cactccgagg ccgaggcgaa tatcgctcgc ctgaacgaat cacagagcac gcacctgctg
    18301 agaatcggag gtgcgcccga tacccatttg ggtgatttgg ctcgcgagga cgctttctct
    18361 gagccgaatg tacgggaact ggtcctgaaa tatgttatca tcgttcttgt ccttttgctg
    18421 atccctgcca tcaacatgag cggtatcacg caaagccgga tgcgtaaacg tatggcggag
    18481 atcggggtga ggaaggcgtt cggggcgaca cgctcggaat tactgacgca ggtactctac
    18541 gagaatctgt tgcagacctt gctgggaggt gtgttaggtt tgtttttctc atacgcctcc
    18601 gtactgctct tgtccgattg gttgctagat acgggcacgg catcgatggg tatcggtcgc
    18661 accttcgtca atgcggagat gatgttcaat ccattgatct tcctttatgc gttccttgct
    18721 tgtcttgcgt tgaacctgct gagcgccggc atcccggctt ggcgagcctc acggatgcgt
    18781 atcatctcgg ctctcaacga gaatgttcat taatctcccg cattggatga tagctatact
    18841 aaaataatag aaagatatga tacgacattt attacaattg atctggaacc agcgcaagca
    18901 aaacgcttgg ttgtgggctg agctattgct ggtctcggtc ttcctttggt tccttgtgga
    18961 ctacctgtat gtgatggggc gcacgtatac ggctcctctg ggcttcgata tccggcatac
    19021 gtacagcatc gtgatcagca gcctctcgga aagaagcccg gattatatcc cgaaggagaa
    19081 gcgggagcgg ccggatggtg ttcatctgct gacggcgttg gatcgcatcc gcacctatcc
    19141 cggcgtggaa tcggcctgcc ttacggatgg ggggatgcct tattatatgg gaagccgtaa
    19201 cctcgtttgg cggattgata cgttgcaggt gccctgccgc tatgctttcg tcaccccgga
    19261 gttcttcgac gtgttccgta tctatgacaa ggagggcgag acggcttcct tgaaacgggc
    19321 catcgaggat aacaactcca tcgtaatctc cgccgacgtg gagacgatga atcccggcct
    19381 ttccctactc gggcaaaagg cgtaccgggg gaatgtgacc gacgagatcg aggagacgat
    19441 ccgtggtatc agcgtcccca tccgccgtca tgagtacacc aaggcggaac ccaacgtcta
    19501 tagggccctg cggctaagcc ggatggagga aggatactat gaggggatga tagatgccgt
    19561 gcgactctgc gtacgtgtcc gtccggatgt cgataatgct gatttccccg cacgcttccg
    19621 caaggatatg gccgaacagc ttcggctagg caacctctat ctgctagacg tacagccctt
    19681 gtcatatatt cgcgacggtt atatccgttc gatcggcgta gagaacgagg tgaaaacccg
    19741 tgtggcggta gcctgcttcc tattggcgaa tatattcctc ggtatcattg gtaccttctg
    19801 gttccgtacg gaatatcgca aaggcgagat ggggcttagg atggccttag gctctacccg
    19861 ccgtcagttg aactcgatca tggtgggaga gggtgtccta ttgctggtct tggcgttcat
    19921 cccgtcctta gtcatcagct tcaacatcgc ccatatggat ttgatagata cctatcagct
    19981 tccgttcacg tggctgcgct ttgcgatttg cggagggatt acgtttgtct tgatcgtcct
    20041 catgatcatc tgtggcgtat ggtatcccgc ccgctcgaca gcccgcttgg agccggcgga
    20101 ggctctgcat tacgagtgat cagggtagcg tagcctgctt tcgggagtgt ccgataacga
    20161 gccagatgtt cgttatcgga cactttttta tgatatggct gttgatatac agctgcttac
    20221 gtctttggca cagcatttgc taatagatag ataacagtca taaaaacgaa cacatatgta
    20281 taggcaatat tttagacaag ctctacagat gctgaaagaa agccctttct tcagcgtgat
    20341 taccattctg ggcacggcct tggcgatctg catgatcatg gtgatggtca ttgtcttcga
    20401 gatacaaaat aaaggcttca agccggagtt gaaccgggat cggacgcttt atgtgaagga
    20461 cgtggcgatc acgcataaga atgaggagga tggcggtatg aactattccc ttgtcggtgg
    20521 ccgtgtggct aaggagtgct tctttacgct gaaaaccccg gaggccgtca gcatgcaatt
    20581 gatgcggatg caaacgctgg tcacttccac ggatcaaacg agacggatga aatgcgatca
    20641 gatacggacc gacgagggct tctggaagat cttcgatttc gagttcttgg cgggaaaacc
    20701 attcctgcgg agcgatgtgg agagtaatat caagaaagcg gtgatcagtc gtaggttggc
    20761 actccgtata ttcgggttgg cagacgagag cgtgatcggg caaacgatat tggtggcacg
    20821 ccgtccatat gtggttggcg gtatcgtgga ggacgtatct cctctcgcca accgtgcgta
    20881 tgcccagatc tggattcctt atgctcaatc cgatgtggat cggctgataa acgaggagac
    20941 attggagggt ctgatcggta gttatcgggt cttgatattg gctcgctcaa gcggtgactt
    21001 caacaagatc aagaccgagg tggagcaaaa cgtagcccgg tttaataatt ccttgcaaga
    21061 actcaagatt gacttgatga agcagccgga tacgcagatg gagagccgcc ttcgcttgtg
    21121 gagtaatgtc gtgcccgacg tgccgagaat gttggggcag tatgcgttgg tcttgatcgt
    21181 cttgcttctg gtcccggcta tgaacctcag cgggcttaca gcgtcgagga tgcagaaacg
    21241 catgggggag ctgggggtac ggaaagcgtt tggtgcgaac cgtggcacgt tgatacggca
    21301 ggtactggcg gagaatctcg ccgtgacgtt attgggcggg gtgttgggat tgctgttctc
    21361 ctatgtggcg gtcttcttgc ttaaggattg gctgctaggc tcgttcgagc tggcttcctt
    21421 gaatagcggc ctgacgttga gcgcggggat gttgatccgt ccggctatat tcttctttgc
    21481 tttcctgttc tgtttattac tgaatctgct gagtgcggct atcccggcgt ggaacgcctc
    21541 tagcgggaat atagtggatt cattgaatga taagtaataa ccggttttgt taattctata
    21601 attcgtcact gatatgataa agcatctagt aaagatcatc tggaaccaac gtaggcgcaa
    21661 tggatggatg gccgccgaga tcctgctggt attcgtggtt ctgtggtaca taatcgattc
    21721 gctaatggcg gttgggaaag tcttcttcgc cccgatggga tgggatatcg accatgtcta
    21781 ttggatctcg atgggcgtgg aggaggtaga ccggaacgag atggattcta cctatcgata
    21841 cgtcacttcc ggacgcagca tgctgacggc gatcgaccgt atcaagacct gcccgggtgt
    21901 ggaggcggtg ggcgcggggc tgatgtccat gccgcatacg ggagagaacc ggtacatgca
    21961 ggtagacgtg aacgattcta taaatgttga gtacgtgaag ctactggaag tgacacccgg
    22021 ttttctggag gtgtttaatt tccgtcccat ggagggcgag aagaaggatt gggaagagat
    22081 gctgaacggg cgtcaggtcg ttctttccgc cggcctgttt agggaatttc aggagaaagg
    22141 cggcaaacgg gatgagggga tttccttctg gggggatagg cgatcgatcg gtggggttac
    22201 cgccgatttc cgtgccgacc gtttcacgaa aagctgtagc tggctgttca tgcctttgac
    22261 ggatgaggag atcgccgagg acgataccga tttccatgtg aagatcgccg tccgggtaaa
    22321 cccttctgcg gatcatgatt tcccggagtt cttcgtgaag caaatggaga agcaactctc
    22381 catagatcgt ttgtatttgc tggatgtcat cccatactcg gacttgagat atagcatgga
    22441 attaaggaat ggcgtaaaat ccgagttgca gaaccagata gccgtgatgg gattcttgct
    22501 gttcaatata ttcttgggga tcatcggcac gttctggttc cgcacggaac aacggaaagg
    22561 ggagatgggg ttgcggatcg ctttgggttc cacccgtttt agcttaaagg ggatcatgat
    22621 tgccgagggg gtattattgt tgacattgat cgctgtcccg gccttattga tctgttttaa
    22681 tcttcatgtg tcggaattga cgaaaggatt ctatatggat tatacgatag cccgttttgc
    22741 ggcggggttc cttataacct acttagtcat ggcggtgatg atcatcttgg ggatatggta
    22801 tccggctcat caaatggcac ggttggaacc tgcggatgcc ttacggtatg aataacactt
    22861 tttgtttaac atattacact tacacacaat tgaaagcccg gtcttgtagt gatacatggc
    22921 cgggctgttt tcgtgtttgg caaaaatttg cgagttaaaa cgtcattgac gcatataccc
    22981 cataatgccc gtctcccgct accgggctga tagacaggtt atgtttcttt gcgaacggac
    23041 gggtaaagat ataggcgcta ccggcgccga taacggctcc cgccgccacg tcccaccaat
    23101 catgcttctt cccatagacc cgactccaac ccacgtaggt agataccgca taagccggaa
    23161 taccccattt ccatccataa cgcctttgga taaaagcggc tcccgcaaag gatacggagg
    23221 tatgcatgga tgggaacgaa tgattatcgc tgaagtcggg ccgctctttc ttcactaggt
    23281 atttcagcgc ataggttacg cccaatgtcg taaccccggt gaatacgcct tgtttcagcc
    23341 cttgccaatc ttgggttgcc aatacggtcg ctagactcgc caccggagtg ataaacacca
    23401 atacgtctcc cgaggtccgt acggctttcc ggctaccggt caccttcaat tcttgtccgt
    23461 taacggacag gcatagcatg agcattgtaa ttgcgaaaag gatatgtctc atagatttaa
    23521 aatatagttg ctattttagg tataaaaatg acgaacccga cgattgctgc cgctatcgcc
    23581 atcaataata cagctcccgc cgccaagtct ttcgttcgct tgatagcctc attatactca
    23641 ggggagacca aatctgctag ggcctcgatg gatgaattga ccgcctcggc agctaatacc
    23701 gctccgatca cgatcgttac tgcgatccat tccatgcggg aaagtccaaa taccattccg
    23761 gcgataagta cgcaaactgc cgcgaaacaa tggatccaag cgttatgctc cttcgtgatc
    23821 aatagcttga ttccgttgaa agcgaattta aagcttctgg ctctctttcg aaatgtgaaa
    23881 ccgtcattct tcatttttat agcatctctt attgaggagg gcaaatatag gtattttttg
    23941 cctttatcgc atatcctgac gaacaaacag gatattcacc tttcatattc cgcaattcgt
    24001 caagattact tgttggtttt tatctggaac gataacttcg ttgattaaaa aagtacctgt
    24061 gatatgagca tagatcaaag taaaagaata aatttatggc ttgaaatcag atatgaagat
    24121 aaaatataac tttctaagtc cgttgctaat ggcgatattg acgatctgtt gcctgtggat
    24181 tgttacggat gtcgcttatg gtgtccgcat gtgggaactg ggagtggacg cgtggatcgg
    24241 gcgtatcaag gcccttgcta ttatattgat cggcgttagc ttatcttatt tgttttttaa
    24301 ttacttggct aatacttttt tagataggaa taaagagcgg aggtcccgcc cggtattccg
    24361 ggaatatcta tgggtggtct tgtttaattt agtcgtgctc aatatcggct tatatatcgt
    24421 gatctattct ataaatggaa cgacctatcg gtggggagag gcgttaatga tcaatgcggt
    24481 agctgtgccg atctttctcc tatactattt cttgatccgt aataatatat tagccaaacg
    24541 ctattcggag aaaatcgttc aattggagaa actgagagta gatcagctgg aaacgcaatt
    24601 gaagctgctg aagatgcaat accatcccca tttcctgttt aatgccttga atacgatcta
    24661 tttcttgatc gatgaggaaa atgaggaagc gattgaggct gtagagttac tttcggactt
    24721 actccgttat caattatatg atataaatac gaaagtgacg atcgaagagg agattgatta
    24781 tttgcgaaca tatattcaat tccagcgact tcgtatgacg aaacgcttac agttcgagga
    24841 gtcctttgac ccggaattga ccggacaaaa aatacatccg ttgcttttcc agccattatt
    24901 ggagaatgcg tttaaatata taggcggagc gtatcggata caagtatcta tgcggaaaga
    24961 gggggcaaag gtctgtttgg gggtaagcaa tactttcaat ccggatttct tggaacaaag
    25021 aaaggggaaa ggcattggga tcgacaatct gagaaaacgg ttggaactat tgtacccgga
    25081 taaacatgag ttacgtataa aaaaagacaa tacccgtttt agggttgagt tatgtattga
    25141 tttatcagaa taatatggaa ataaagtgta tcataacgga tgatgagcca atcgccagaa
    25201 aaggacttcg gcgacacatc ggtaaaattg attttctgac catcgtcgga gaatgtgagg
    25261 acgctataca actcaataat atgctgaatt cggttcaggc ggatttgctt tttctggata
    25321 tagagatgcc ggatatgtcc ggactggact tcttggagag tgctcagaac gctcctaagg
    25381 taattatcac ctcggcatac gagcggtatg cgttgagagg atatgagttt gacgtggtgg
    25441 actatttatt gaaaccaatc tctttttccc gtttcctgaa atcggtcaat aaagcacatg
    25501 cgttgatgga atctacatcg aaaagcgagg agcccgctta tatcttcgtc aagacggaga
    25561 agcaacttaa aaggctttat ttaaaggaga ttcaatttat agagggcatg gagaactata
    25621 ttgttatcca taccctcact tccaaagaga tcgttcatct ccggttgaag agtatacagg
    25681 aaacgctgcc ggcacaaatt tttatgcaag tgcaccgctc tttcatcgta aatctttctt
    25741 atgtacaagc gatagaagga aatctattaa tcattgggga gcataaaatc ccggtgtcgc
    25801 gtcctttacg ggaagaggta tataaatcga tcgtcaataa tcaactcatt caaagataag
    25861 tatccaaaaa cgaacacact gttcattatc gaacacttta aatattccta tttatcggat
    25921 tatcaatagt atatgttttt ggcatgcctt ttgccttagg cagggtaaaa aaacttatac
    25981 taagatgaga aggatctata tagcgatgtg ttgtctgtgg gcggggattt cgggagtatg
    26041 tgcccaagac aatacgaata aagttcgaat aaccctgcgg caagcgatcc agatcgcaca
    26101 gcttcaatcc gtagacgctg ccgtggcgct caatgagttg cgaacggcct attgggaatt
    26161 ccgtacgcat cgggcggatc agttgccgga agtgatattt acggggactc tgccttcata
    26221 tagcaagcaa tactcgaagt accagcaatc ggatggttct tatacctatg tgcaaaacaa
    26281 tgccttaggc ttaaatggag agatctctat cgcccagaac atagccttga ccggaggtaa
    26341 gatcgccttg aatacctcct tggattttac ccgtcagcta ggtagtggcg cttacaacga
    26401 gtttatgagc gtacctgtta gtttgacatt gacgcaaccg atcttcggcg tgaatgacca
    26461 aaaatggaaa cgtcgtatcg agcctgttcg ttaccaagag gctaaggccg cttatatgga
    26521 gaacgtggag aatgtaacga tcgctaccat cacgaattac ttcaacttac tgttggcgga
    26581 agataatctg gatatctgta atcagaactt gctgaacgcc aataaactct atgacatagc
    26641 ggtagcgaag cgtaagatcg ggcatatctc ggagagcgag ttgatgcgtt tgaaacagtc
    26701 ggccttgcaa gcgaaaggta agctaaccga ggcccaatcc aattataacg cgatgatgtt
    26761 caagctccgt tcctttttag ggatgagcga gcaagacgtg atcgagcctg ttcttcccga
    26821 ggcgatagaa ggggtccgta tggattatca ggcggtattg gagaaggctc aagaaaataa
    26881 ctcattctca aagaatatca tgcgccgcca gttggaagcg gattatgatg tggcgaccgc
    26941 caagggaaac cgtcgaagta ttaacctgtt tgcctccgtg ggttataccg gtaaggatat
    27001 gtccatgcga ggagcttaca acccgttgaa agataaccag atcgtagagg tcgggctttc
    27061 gattcctatc ttggactggg gaaaacggaa gggaaaggta aaagtagccg aatcgaatcg
    27121 ggatgtcgta ctttccaaga tccgtcagga gcaaatggat tttaatcaag atatcttcct
    27181 cttggtggag aatttcaata atcaagccgc tcaattggag atagccgccg aggtggacac
    27241 gttggcggaa aagcgctaca agacctcgat cgagactttc atgatcggaa agatcgatat
    27301 cctagacttg aatgacgccc agagttcgaa ggatgacgcg aagcaaaagc atatccaaga
    27361 actgtattat tactggcgtt atttttataa catccgtagt ataacattgt atgatttctt
    27421 gaataatcgt acattagatg ccgatttcga ggaaatcgtg aaacgataaa ttgattatat
    27481 gatactgata atagatgatg atgcggctgt tcgttcctcg cttacattcc tgctaaaacg
    27541 tgcgggtttc cggccggagg cggttccggg gccgaaggag gccttggagg tggtccgtgc
    27601 cacggcgccg gagctgatct tgatggatat gaacttcacg ttgactacca cgggcgagga
    27661 ggggattcaa ttattgagac aggtgaagat ctttcgtccc gatgtacccg tgatcttgat
    27721 gaccgcttgg ggatcgatct ctttggccgt gcagggaatg caagccggag ccttcgattt
    27781 tatcacgaag ccttggaata acttggtatt attaaaatcg atccggaccg ccttggaact
    27841 gagcgagcag aagaaggagg caaacgctcc cttgaaccgt tcggatgccg atcataaatt
    27901 tcattttgat aagatcgtgg ggcaaagtgc cgctttgatg gatgtcttgg ggacggtctc
    27961 gcgtatcgct ccgacaaacg cctctgtctt gattaccggc gagagcggta cgggtaaaga
    28021 gctgatagcg gaagcgatcc atgcgaatag cccccggtcg aaagaggctt tcgtaaaagt
    28081 aaacctaggc ggactttccc aaagtctttt tgagagcgag atgttcggac ataagaaggg
    28141 ggcttttacg gacgcgtaca tggatcgggt agggcgtttc gagatggcga acaaaggtac
    28201 gatcttcttg gatgagatcg gcgatttgga actgtcttgc caagtaaagc tgcttcgggt
    28261 attgcaagac cagacctttg aggtcttggg ggatagccgt ccccggaagg tggatatacg
    28321 ggtcgtaagc gctacaaatc gggatttacg atcgatggtg gcggaccgta cgttccgtga
    28381 ggatcttttt taccggatca atttgatcac ggtgcattta cccgccttac gtgagcgaag
    28441 ggaagatatc ccattgctgg cccggtattt cgcggataag caatcggaga tcaatgggct
    28501 accgagggtg gagttctcat cggatgccca gacctattta agccgtctcc cttttcccgg
    28561 taatatccgt gagttgaaga acttggtgga gcggacgatc cttgtgtcgg gtaagacgct
    28621 tttggatacc gctgatttcg aggttcattg catgaataca tccggtgcta aatcgacgat
    28681 tccgccttct ttggagggct tgaccttgga tgagttggag aagcaaacca tcttacgctc
    28741 cttggaagcg catggaggta atttatcgca tgtcgctacg gcgttgggaa tcagtcgtgc
    28801 cgccttgtac cggagattag agaaatacgg aatcccgatc gataaataag aagaggcaag
    28861 gatgaggctg aaaggactat tctggatatt gacgacgctg ctgttgacta tattggcggt
    28921 ggtgacttat tatgtctttt atacgtcttc tatccggatg tttttcgcgg tagaagcctt
    28981 ggtcttgctt acgatcatct atttatttgt cttttatcgc cgtatcataa agcccttgca
    29041 tatcatcggt aacggtatgg agctgttgaa agagcaagac tttagttccc gcttgggaaa
    29101 ggtcgggcaa acggaggcgg accgggtggt cgatgtgttt aataagatga tggagcagtt
    29161 gaagaatgag cgtttgcacc tccgggagca aaaccatttc ttggacttgc tggtcaacgc
    29221 ctctccgatg ggagtgatca tcttgaactt ggatgaggag attctatcca tgaacccggc
    29281 cgcatgtaaa ttgtttggcg cgcaaagctc ggaggatatg gtgggaaaac gttttcttca
    29341 actagattct cccttggcgg aagaattggt acgggttccg atgtatcaag cgcaaaccgt
    29401 ccggttgaac gacgctaata tttataaatg tacgcattcc tcatttgtgg atcgaggttt
    29461 tcaccacccg ttttatttga tagagacgtt gacccaagag gtgttcaagg ccgagaagaa
    29521 agcgtatgag aaagtgatac gtatgatctc tcatgaggtg aataatacga ccgcgggtat
    29581 cacctctacc ttggatacgt tggagtctac tttcagcggg atggaagata tggaggatgt
    29641 ctgcgaggtt ttgcgggtct ccatagaacg ctgctatagc atgagccatt tcatcaccaa
    29701 tttcgccgat gtggtgcgta tacccgaacc ccaaagtcgt ccgcaagaat tgaaccaagt
    29761 ggtgtccgct tgtaaacgct ttatggagac agtttgccag aaccggaata tcgagattgt
    29821 tatggatctg agcgaggaat ctccagtcgt gaatttggat aattcattat tcgagcaagt
    29881 cttggtcaat attatcaaga atgccgccga atccatcgac cgggacggaa agatctatat
    29941 ccggacgaca gtgcgtccta cctgcttgga gatagccgat acgggcaagg gcatcgacaa
    30001 ggaaacggaa acgaaactgt tcagcccgtt cttctctacg aaaccgaacg gacaaggtat
    30061 cggcttgatc tttatccgtg aggtgctgtt aaaacatgat tgccgattct ctctccgctc
    30121 ttatgcggat ggattgacaa ggtttaagat ttggtttagt tgaaataatc cctttatggt
    30181 ttgaggtttt tcccttgtag gctaaggctg tattcttaca ggtgttagcc tttttgtctg
    30241 cttgtattca tcatgcaaca gccgttgcat gatcatctac caactgttgc acgatcttct
    30301 accagtcgtt gcatgatcgt ccaacagttg atagatgatg gatgtctctt gaggaaaagt
    30361 ctaaagatag ggatggaaag ggctaaagga tatggaggtt ttgggcaagc tgtactggat
    30421 tttatactat ctttgggccg tataaatgca atagaaatct aatcttgaat atcatgaaga
    30481 aagtagtatc tgtattattt atccttgcga ttatcgtatt ttctgtatta atggtaagct
    30541 attcgagtga tcaaaagccg gagaaagttc ttcgccatgt tgttatgttc ggttttaagc
    30601 cggatgtgtc cgaggcgcag gtgaaagagg ttgaggatgc cttttgtaag ttgccttctc
    30661 aaatcgactt gatcaaagga tatgagtggg gaacggattg tagtccggag ggattgcaac
    30721 agggcttgac tcattgcttt ttcttgactt ttcattcgga tgcggatcgg gacgcctatt
    30781 tggtacatcc ggcgcataaa gcatttggca aggtgttagg agggaaggca tcggcggtta
    30841 cggtgttgga ttattggacg aaataaaaag aatgggcggg atgaatcgat gagtcacccc
    30901 gcccgttttt atattcctta gttactttat attataacca ttgattcatg aactgatcca
    30961 tctcttccgc atgggcttct aggctttgaa gtagcttgaa ttgggctttc gtacggatta
    31021 agttatgttt cgggctatgg atcttgtaat aggtatcgcc gttgatataa tcggttaaga
    31081 aacgaacggt ctgcatataa gtcaataagc gtccaccgta aggtagcaat ttgatctcgg
    31141 taggagttaa gaacgccttg gccttttcca tgtatccacg ggtataggct ttgaatatct
    31201 ccatattaac gtttacgtta tccagattct catcgtcctc ggcacccgta ttggctccgg
    31261 tacggataaa gtcgccgata tcggaaagga cgaagcccgg catcacggtg tccaagtcga
    31321 tcacgcaaag caccttgtcg ctatcagcgt caaacatcat attgttaact tttgtatcgc
    31381 aatggttcgt gcgtttcttc aattggccct cacggtacag gcgttcttga atgcacatcg
    31441 cttcggcacg tttctcgatc tcctctacca aatctttcac ctcttccaac cggcctgccg
    31501 gattagcggc tacagcctca tggaattgtc gcaagcggaa ctccatatta tggaaatccg
    31561 ggatggtctc gcccagcgta ccctcgggta tatcggacaa catggtctgg aaatcaccga
    31621 acgctttgcc agcctcataa gaaagctcag gagttacttc ctcatagctt ttgctgcgag
    31681 ggatgaatag gcatacccgc caataactat ctccatcgaa ataatatttt ttcccgtctt
    31741 tagtcggcaa gaaggttaat accttacggt cgatatccgt ttcacctttt tcctccagct
    31801 ttttgcggat atgagtggta accacatgga tgttattttg cagcatatcc acattggtga
    31861 agattaaatg gttgatacgc tgtagcacgt atttgatctc ccctttctcg ttggtcactt
    31921 tcaatgtatc attaatgtgt ccgtttccga atggttcagc ggaaactact ttctcgtcca
    31981 actggaactg atccaagatg tttagtaatt gttctttcgt ttttgccatg atatttcatt
    32041 atgttaactc cggcaaagat acaaaaaaag gccacgatac aaatcgtgac ctttttttat
    32101 ttcttaaaga aagaaatctt atttcttgtt acggttacca taacggctca tgaacttatc
    32161 aacacgtccg gctgtatcga ccaacttaga cttaccagtg tagaacgggt gagaagtgtt
    32221 agagatctcg acctttacca acggataagt tacgccgtcg atctcgatcg tctctttagc
    32281 gttaatagta gaacgagtga tgaatacatc atcgtttgac atgtccttaa atactacagg
    32341 acgataattt tcaggatgaa tacctttttt cattgcttta ttatctattt taatttatac
    32401 tctgtatata tttggtaacc ggtattttgg cttgcaaagg taagggtttg ccacaaacaa
    32461 acaaagaaaa tcgtattatt tttttcaagg gcgttgattt tgtgttattt tatatgcttt
    32521 gaagcatcat ttgtcgtgaa tcttgattat ctttgtgcaa gtttttaatc attaacgtaa
    32581 taacataata acaactatgg taaattacaa agatttgggc ttggtgaaca caaaagaaat
    32641 gttcgctaag gctatcaagg gcggatatgc tatccctgct ttcaacttca ataacatgga
    32701 acagatgcag gctatcatca aggctgctgt agagacaaaa tctccggtta ttttgcaagt
    32761 ttcaaagggc gctcgccagt acgcaaacgc tactttgctt cgttacatgg cacagggtgc
    32821 tgttgaatat gctaaggaat taggttgccc gaatcctcag atcgttcttc acttagacca
    32881 tggtgatacg tttgagactt gcaagagctg tatcgactct ggcttctcat ctgtaatgat
    32941 cgacggttct caccttcctt atgaagagaa catcgctttg actaagaaag ttgttgagta
    33001 cgctcatcaa ttcgatgtaa ctgtagaagg cgagcttggt gtattggcag gtgttgagga
    33061 tgaggtttct tcagaccacc acacttatac caatcctgag gaagttatcg acttcgctac
    33121 tcgtacgggc tgcgattctt tggctatctc aatcggtact tctcacggtg cttataagtt
    33181 cactccggag caatgtacga tcgaccctgt tacaggtaag atggttcctc ctccattggc
    33241 attcgacgtt ttggacgctg ttatggagaa acttccggga ttccctatcg ttcttcacgg
    33301 ttcttcttct gttcctcagg aagaggttga gactatcaac aaattcggtg gcgctttgaa
    33361 ggctgctatc ggtattcctg aagagtggtt gcgtaaggct gctaaatctt ctgtatgtaa
    33421 gatcaatatc gactcagact ctcgtttggc gatgactgcc gctatccgca agactttcgc
    33481 tgagaaaccg gctgaattcg atcctcgtaa atatctgggc ccggctcgtg ataacatgga
    33541 gaaactttac aaacacaaga tcatcaacgt tcttggttct aacgacaagt tataatcgga
    33601 agtttcttga tataaataaa gaaagccatc tcggtatcgg gatggctttt cttttggtct
    33661 gtagtttagt cttttaatac cttacgaagc gcttccaaca tcggatctac ggtaagatcg
    33721 ttgccggtag cttgcttgat ccacacattc ggggtgaggc ggccttgctt gaatatccgg
    33781 ctaacctcat tcgcgaaatc cttgccattg aggtagttct ctagctggaa ctcgataatc
    33841 tgtccgaaag cgtaggcgga aaggtagagc ggataaccga tcatatggga gtaaatcgct
    33901 agaacggtct cgtcttttac accgaatacc ggagcgtaat acttattcca gatttccttg
    33961 gaaagacgga tcacggcctc ctgcaattcc ccggcggtag cgttaggatg tgcgtacatc
    34021 catttccata cggagatatc cagcatggaa acaccgcaaa tctcatacat gctccatatc
    34081 ttatccaaga tatccatctt ttctttttcc ggattctcgt cttttatgcc cagtaactca
    34141 aggtctcttt tctggaagac aaaggccagc gcttcggtga aagccgtatt gggaactccg
    34201 ttgagcatat aataatcgac atcatataat gagatcgttt gctctacgtt atgtccgaac
    34261 tcgtggatgg cgatattata tcctttgtaa tccatccctt gtgaagggat acgggtacgt
    34321 aaacgggaac gctggccttt catggaggct ccccacgcat gaccggaacc acgggcggga
    34381 tcgactgcga tcttatccgc tagatattgg gcacgatcgg ggctgaatcc tagtttctgt
    34441 aatatttccg gtagcttctt ttccatcgtt accgcatcgg gatacagggt acgggtttgc
    34501 tcgtttagct tgttctcgtc cagattgcta cgggccttga agccatcgta ccatatatcg
    34561 taggcttcca gtttgcgtcc gaggcgtttg gagatgattt tccccacttc ctttagttcg
    34621 ggggcggaaa ggaattgatc gaacagggct tctacatcgt tgacatctat ttccatatct
    34681 tccgtgaact tacggtctat ataggtgttt cccgtatatt tgtctatacg ctgcatggcg
    34741 ttgaagttat tcaacatttt ctgatagcgg gccgggcttt caggggtacc ttctagttca
    34801 tttcctgctt gagataacgt attggcgtac gggttccatt cgtaacgatc cgagttgatc
    34861 acctctttcg ggatttcttg cgagatgatt cgcttcatga tctcatatac catccgttgt
    34921 ttttccaatc cctcttttcc tttgttataa ttggccttga tctcgtcgcg aaggttccaa
    34981 tggcaaagta agcgcatgtc ggaggggaaa atggtttttc ctttaggagt tagtaaatgc
    35041 cccatataga tattataatc cgctatgtaa atatccgcgt cactttccgt atctgcggcg
    35101 gcttgcttta cttccgccgg tatccgttcc gtaaacatat cgcctagccg ggcgtaggcc
    35161 catgctttac ggtcattccc taacgcctct ttctccttga gagtaagttg gggaaagttg
    35221 agggcgatga tgaagccgat cttgttggcg tatagatcgt ccattaggtg ggaactgggg
    35281 ctgtaggatc cgaatttctc atcgatggcg tgtagaggtc cggtatctag gttcaaattt
    35341 cgttgcagac agagtaccat ctcgttgaaa ttgccattga taccttcaat atactcgctg
    35401 atcttgagga aaacttggtc tttttcggcg ggatcggata gataattctc ccggcagaag
    35461 gtttgaaacg cttgctcatc cccatcggag gtttgccaga ggcgggctac ttgctcgaca
    35521 ccctttgtga ttcctgcttg attcttagcg tccttggcta ttagctcgtc aatcgtagct
    35581 tttacgatag aaggctggat gctggcttgc ccttgcataa agctaaaggc gcaggccagt
    35641 aacatacaaa tacgtacgac ttgctttctc atggtatgtt tgtataaagt tatttaaaac
    35701 aaatgtatga ataatattcg tatctttggc cgatttttct aattgagtaa aaaacaaaga
    35761 gatgaaaaag ttactatgta tgtggatggt cgtatgcggc cttttgttga ttcccggaaa
    35821 catgaaggga cagtccttga aagatatctt aaattcatct gccgtaaaga acgccgtgac
    35881 ttctgtcacc ggagggaaag ccgtgacttt cgagaattta cagggaactt ggatgtatgt
    35941 gaaccctgcc ctgcaactgg aaggtgataa tgccttgaag aatgtagcgg gaagcttggc
    36001 tgctaccgag gcagagaaga aaatgaagga atattgcgcg aaagtaggta tcgtggaagg
    36061 tgtatttaat tatgtcttta attcggatag tacgtttacg agcgcgttga aaaggggaag
    36121 cctgaaaggt acttactcgg tgagtccgga agataaaacg gtgacgttac ggtatacggt
    36181 gggtaataag aagctgaccg tttctacgct taccgcccat gtcgtccttt ctggtaatga
    36241 gttgacattg ctttttaacg cggataaatt actgaagttc ttgagcacgg tttcttctat
    36301 atccagcaat acgaccttga aagctatcaa taagttggca agtgaatatg atggcatgat
    36361 gctgggtttc gatttgaaga aataatgtaa tatgatacga tttataccga ggcgttattg
    36421 ggcagtaata gcggttgcgt tggcattgac catgtccgtg ttggacggca cgattgtcaa
    36481 cgtggcgctt cctaccttgt cccgtgaatt cgggacatcc ccttcctcca cgatctggat
    36541 tgtcaacgct tatcagctaa cgattacgat gtctctttta tcgttctccg ctttgggaga
    36601 tatttatgga tataagcgga ttttcttgat cgggacgaca atattctgct caacgtcatt
    36661 attttgtgcc ttatcctcgt ctttcgccat gttgacggtc gcgagaatat tgcaagggat
    36721 cggagcctcg gctatcatga gcgtgacgac cgctttactt cgtattattt atcctccaca
    36781 atatataggg cggggaatga gtatcaatgc catggtcgtg gcggtatcga ttgctgccgg
    36841 gccgtcgttg gcgggcgcta tcttatcagt cgcttcttgg aattggttgt tcgctatcaa
    36901 cgtaccttta gggatttgcg cgattataac gggttatttt cttttgcctc aaaatccttg
    36961 caaggatggg ccgaaacgaa agtttgataa gatcggtgga atctcgaatg ccctgacttt
    37021 cggattgctg atttattcgt tggaaggcat cgcccatcat gagaactgga gaatgatcgc
    37081 tttacaggtt cttcttctat tggtgatcgg aacatttttt atccgcaggc aactacggca
    37141 ggaggttccg atattgccat tggacttgat gcggattccg atattcgcct tgtccgtatt
    37201 atcctcgatc acttcattta cggcacagtt gttggcgatg gtatcattac ccttttattt
    37261 gcaaaatgtg gccggaagaa atgaggtgga gacggggctg ctgttgactc cttggccggt
    37321 agcgacgatc ttgaccgctc cggtagccgg gaggctgatc gagaaatatc atcccggatt
    37381 gttaggcggt atcggaatgg tggtgtatgc gaccggactt cttctattgg ctttattgcc
    37441 ggggcaaccc accaatatgg atatcgcttg gcgattgatg ctttgcggta tgggtttcgg
    37501 cctgttccag accccgaata atagcacgat gatatcggcc gcccctcgtt cccggagtgg
    37561 cggggcgaac ggtatgcaag gtacggcacg actgttgggg caaacgctgg ggacgacatt
    37621 tgtcgctttg atctttagtg ttacctctgc caccgatagt atgccggttt gtatgtatgt
    37681 agcgatcggt ttcgctttag tcgccgctat cgtgagttgt ctccgtatct cacagcccgt
    37741 tcccatgcgt ggaaggtgag taggaagata cgatttctaa tagggtctca ccgtagttct
    37801 ctatgatctt tttgccgatt ccgggtatct tcaacagttc tttcgagttc gtgggcaaag
    37861 tgttgcaaac gccaattaag gctttctgtt gcaagatcgt gtaaggaggc aactcctttt
    37921 ctacggcaag ctcgtatctc cattgtttca aacgggcata tagctcagga tgtaagacat
    37981 ccgtggagac ggggatcttt tccgcttccg tcgatttccg cgtcgatttc tgcttgctgg
    38041 caacagccga ctcctcaatg ttcgctttag ccttggcgga tagatagtcg atgagacgaa
    38101 aaccatcttg gcaggctttt aatgtagcga ccttgatcgt aagctcatcg ctgaaagctt
    38161 ttaatgcgga tgtaaatgcc ttacgggcct ctttattgtc gatctctaca tcggaagcct
    38221 ctatcaaagg gaggcaatag gtctcgatct tttccagaaa gtaagcgcaa ccttttcgga
    38281 tgcggtcttg tatatgctcg tccgtatcat agagattcgt gctggagatc atacgggtga
    38341 gttgctggca gaaacgttcg cctacttcta ctatatccga acggaaataa tcccgtaccc
    38401 ggggatattg gttgcttaat tccgggtata gtttttgcag atgggtgtat gccgcgtaag
    38461 atgtatattg caacttttgt tgtacgggat tgaagtcgaa tagctcggtt gccaatctca
    38521 aataatactg ttgttgggct tgacgcagtt ggtcttcaca cggttgacgc tccgagaggg
    38581 aagaggtata acttaatatc ttctcatcgc taatcatggc gtttcgagtg atcgggctac
    38641 ttaataccat tccttccaat gtcttgcaac ggctcaaagc aacgtagact tgtccgtgtg
    38701 agaaggcggc ggatgcgtcg atgatggcat gctcgaaagt caagccttgg cttttatgga
    38761 tcgtgatcgc ccaagcggtt ttcagtgggt attggctgaa agagccggcg attgtctccg
    38821 tgatatcctt cgtgttctcg tcgatcgtat atttcacgtt tgtccatgtc tcccggtcta
    38881 cggtgatatc gtttcctaat tcgtcggata cgataatctt gctcgggctg atgaagacaa
    38941 ttcggccgat ctttccgtta taatatcgcc tttcgccgga agagtcgttt tttacgaaca
    39001 tgacttgagc gtcttgcttt agctccaata cctcgtcggt cgggtaggag taagctggaa
    39061 agtcatcctt gatctccgcc ttgtacgtat aagccgggcc gggtaattct tgcaacttcc
    39121 ggttattgat ttgctgggct tgataattat gggttgtcag cgtgatataa cctgctttgt
    39181 catttggttt aaaattgggg atataacgtt ggtttaaggt gtgtagcgta ttctcgtcga
    39241 agcggttttc ccggatattg ttcaataagc gtacgaacgt atcgtccgct tggcgatata
    39301 cttgagttaa ttcgatgcaa agataatcac tttcggaaag agccttactg tcaaaaaaga
    39361 agggagaggc gtaatgttct ctcaacaaat tccattcgtc ctccttcgct acgggggcta
    39421 attgttgtaa atctccgatc aataataatt gaacgccccc aaagggttta ttcctatccc
    39481 gataacgacg tagcatatca ctgatagcat ccagcaaatc ggcacgtacc atactgacct
    39541 catcaatcac gagcaggtcc atactacgga tgatattgat cttatcccgg ctgaatttat
    39601 gagaatagga tttattttgc ccggaggcca tttcgctacc cggtatatac ggtccgaaag
    39661 gtagctgaaa gaaggagtga atggttaccc ctcccgcatt aatcgccgcc actccggtag
    39721 gtgctaccac aatcatccgt tttggggaag tctctttaag ttttttcaag aatgtggtct
    39781 ttcctgttcc cgcttttccg gtaaggaaga tgttggttcc ggtattttcc agatagttga
    39841 aggcaaggtc caattgtaaa ttcgtctgca tcatatttaa gctgtttagg tgaattcaca
    39901 aatgtacgta taatctttca aacgtccttc tcaaatggaa aataaacgga gtaactgcgc
    39961 taaaatctac atcccttttt cctttttagg aagagattga tatacgatat cgtaggattg
    40021 ttttataagc tctttgatct tgttgtcggg tacatcttga ttaaaataga cactaatcca
    40081 gtatttttta ttcatatgcc aaccgggtgt tatgccagag tatcgagctt gcaactctcc
    40141 cgattcattc gggtcacatt tgatacagca aaaatcaaat acttcgatat ttacgaagca
    40201 gaaccattta cttcctacat aaaagcaaag aacgtcccga ctgtatttat caggaacatt
    40261 cgtgaaaggc attttttcat aaacaccatt caacgaaagg caatattccc taaactcttc
    40321 aatattcata acattcgtat gtatgataga ttatagcgat atcctataga ctaagaaact
    40381 caatggttgg acggagactt cagtagcggg agcctctagt tccaccgctg attcaatggg
    40441 tatgactgtt tccggtttac ccaatgtgtt cttcgcttct aagtctgagg catgtaagac
    40501 catcaacttt cctttatgct tgccggatga gattccgttt aggtttaatt ggatcttttt
    40561 gctctggatg ccggtattga cgattttgat gatgagctcg tttgtgcctt tgtcgagggc
    40621 ggctgtggcg aatagctcgc tttgcccggt aacggcttct ttgttcatcg tcaggggcaa
    40681 tacgtttgtt ccggcattgt gcccgtataa ttgttgtaca tagtagttag gagttttcac
    40741 gatgtttagg ttgttgaacc agattaagtc cggacgccat tgccacgcat cgacatgtgc
    40801 gaataaaggg gcgtatgtac ataattccac cacgtcggca ttccgttcaa gaccggtcat
    40861 aaacgcagcc tcgcataatg cggtcaggaa gctattctcc cggttagtcg ggtggcaagc
    40921 atattcaccg gcgaacactt tggggccttg ccgatcatac gaatcatatc gtttggcact
    40981 atttaggaac cattccggtg agcgatagaa atgttcatcc accagatcta cttttaagcg
    41041 tttcatctcc ggccatagat attcgaaatc ttttccttcc gaatcaggac cggaactgcc
    41101 gatgattttg atctccggat atttggctcg gatggctttc acgaatggtt cgaggcgttc
    41161 gggatataat ggtccccatt gctcgttgcc gatagcgata aatttcagat taaaagaagc
    41221 cggatgcccc atatccgcac gcactttgcc ccattgggag gtaatcgggc cattggcgaa
    41281 ttcgattaag tccaaggcat cgtctatata aggttgtaat ttatctaccg gcacatgctg
    41341 gtccataccc tcattctcaa actggcatga cagcccgcaa ttcaatacag gcaggggctc
    41401 ggctccgata tcttcgctta attggaaata ctcaaagaat cccaaaccgt aagattgata
    41461 ataatccggg aatttcttgt gaggaaatgt ataattccat cggctgatat tgataggccg
    41521 gttctctacg gggcctaccg tatttttcca ttggtagcgt gtggcgatgg ttgtaccctc
    41581 aacgatacat ccacccggga aacgaaagat tcccggcttt agatctttca acgcttgtgc
    41641 cagatcgcgg cgtaggccgt tcgtgcgatt gttgaatgtt ttttccggga aaagggagat
    41701 atgttccata tccaaagtac ctgccgtttc catcgtgatg cgtaggcgtg atttagcctc
    41761 ggtagctttg ggagacaaga taacggaata tttcttccag tcttttcctt ttatctctag
    41821 gtgttgtgtc tcataaatat cgttatccct gtttactaat tcaatacgta gtttgatcgg
    41881 gttattggtc tcggtacggg catataagga aaagtcgtaa ttttcgtcag cctttatacc
    41941 gatacctttg aagccttcgt tctccagacc ggttccggtg atttgcccgg tataagtcag
    42001 gtgtgcgtaa tgggggtttt tgttgaaaca gggattcttc tcagctatac ttacatcgcc
    42061 gaaaggctcc caacctcccc atggattctc aaactcgaag gagcggttct tgattagctc
    42121 cgcatacaat cctccatctg ccccgaaatt gatatcctcg aagaagattc catacatggt
    42181 tgactggata ggcgagccta ctttctgtat atcgatgtca aactcatgga caggaacgat
    42241 gtcttgtgcg gtcatgcagt ttacacctac acttaagagg aataaagccg cggttttttt
    42301 catgttcttt cttctcatat tctatgtttt tcaataaata aagatttaga caatcaaatt
    42361 cgctatcatc tgtataaaca agatcaggaa taccatcgct atcggataaa ccgtcgcata
    42421 agccacgctt ggggctgggc tgtctgtcat agaatctgcg gcggcaagtc ccggggtact
    42481 ggtcatacca ccggcgattg ttccgactaa atcgagaatg ttgatcttaa agaaataata
    42541 tccagctaat acggctataa tcatagggat cattgttata gcgataccga ctccgaataa
    42601 agttaaaccg cttgattgga aagtggaaac cagatttaca ccggcggatg tcccgacctc
    42661 ggagaggaat agcaataatc ccaattggcg aagcaggtta ttagcggaac cggacattga
    42721 ccagatgatc ggacctgttt ttccgatggc gcttaatacc aaggcaacca taaggatacc
    42781 gccggttagt cccggagaga atgagaagga atccgagaag gatatattta attttccaaa
    42841 caatacgcct aatacgatac ccatagcgat cgggaaaaag tctgtatccg aaagacgttt
    42901 ctcatcattg ccaatgaatt gggcgagttc atttacgctt tctttctcgc cggcgaccat
    42961 caacttatct ccaaacttca acaccaaatt aggttccggg gaaaggtcga ttccgcttcg
    43021 acgtacacgg gttaccgtac aaccgaaagt tccttgtaaa tttaaatggc ctagcgattt
    43081 attgataatg ctcttattgg tcagtaacag ggattgcaag gtctgtccgc cacttaacgg
    43141 cagatctccc tcgatacgtt ctcccaacaa taatgtcagt tgctccaagg ctttgtcgtt
    43201 acctacggcc ttcagtaaat ctccctcgtt aagcgtggta tggggagttg gcatagatat
    43261 gacattgtcg tgttttatac gggagactac cgctccggtc atggcccgta cctgcaattg
    43321 tgccaaactc tttccgcaga tgtttttatt cgtgacttta aatgcggcgg tatgtaatgt
    43381 aggatattgg cttttccgtt gggcttccag cgctttagcc tcggctatca aatccttgcg
    43441 aagcattttg ggcaatagtt tcacgaaaag gatcacgccg attacgccga acggataagc
    43501 gatgccatag gcgatggatg ctgcggatga ttgcgtggag tcgatcgcta ccgccaaacc
    43561 gggcgtactc gtcaatgccc cggcgatcag accgacgata ctcggggtat cgatatccaa
    43621 gatatacttg aataagattc ctgtcaagca tgccgaaccg acaattaata acgtcaggat
    43681 aatgagtgtc ttgcctttgg aacggaagga gtcgaaaaat ccggggcccg cttggatacc
    43741 aatggtaaag atgaataaca ccaaccccat attccctaat tccttgggta tgataacccc
    43801 aaaatgaccg aataacaggg cgatgaaaat aactgccgat acatctagcg aaagaccttt
    43861 gatctgtatc cggcctagca tgaatccaag cgctatgatc agaaacaggg caaaataaga
    43921 agactgaagt aatgtttcaa acatgtcaga tagttttgaa gtgaagctgt taaagatgca
    43981 aaattaaact ttttagccca ttcgggcaac ggcttggcag gatttctgta cctttgtgcc
    44041 atattttaga aaagagaaag taaagagcat aagcgtgaga cgatatttta tatatctggg
    44101 atataacgga aagaattttc ggggctggca gatccagccg aatggtatga cggtgcagca
    44161 atctatagag gaggccttgg ccatcttgat gcgtacgccc gtgcctattg tgggggccgg
    44221 ccgtaccgat gccggcgtac atgcccactt gatgatcgca cattttgatt gggaggaacc
    44281 gatcggggat ttggtattcc tcgcggaaaa attgaatagg ctcctgccca aagatatcgc
    44341 cgtttataag atcgtgccgg tcgtaccgga ggcgcatgcc cgcttcgacg ctacctcgcg
    44401 aacctataaa tattatgtta cgacaaagaa agacccgttt aatcacgagc tggtttataa
    44461 gcttcccggt cgtttggatt tcgaggcgat gaacgaggcg tgtaaggtct tattcgatta
    44521 tatcgatttt acgagtttca gtaagttgca tacggatgta aagacgaata attgccatat
    44581 ccaacatgcg ggttggacgc aagaagggga tatttgggtg tttacgatcc gtgcagaccg
    44641 tttccttcgt aatatggtgc gtgcgatcgt tggtacttta ttggaagtcg gaagaggacg
    44701 tttaacgata gacggcttcc gaaacgtgat tgaggcaaag gatcgttgca aggccggaac
    44761 ctccgtgccg ggacacgccc tgttcttggt agacgtcacg tacccggaag aactctttcc
    44821 agtggaggat taaaccatgt ggttagctct agccttcctc tccgccttct tgttaggttg
    44881 ttacgaggtc aataagaaaa tgtcgttaaa tgggaatgcc gttattcccg ttttattctt
    44941 caatacgctc ataagcagtt tgattttcgt cccgttcatc ttgctctctt tttatacgga
    45001 ttgcttggac gggacgatgg tgtatgtacc ccgtgcctct ttggaggacc atctgaaggt
    45061 attgataaag gcggtgatcg tcttatcctc ttggatatcg gggtattttg ccttgaaaca
    45121 tttgccgctg acgataaccg ggccgatcaa ggccagccag cccgtgctta cattactggg
    45181 tgcgatgctt ctgttcgggg aacggctgaa tctatttcaa tgggtcggag tcttgctttc
    45241 tatcgcttcc ttttatctcc tttcctcatc ggggaagaaa gaggggattc attttgccca
    45301 taataaatgg atcttcttca cggtcctgtc tatcttgacc ggagcgatga gcggattgta
    45361 tgataagcat ttgatgcgta gtatggatgt aatgacggta caagtctggt ttaatgtcta
    45421 tcaatgtgtt atcatgtcat ttatcctgtt gtttctatgg tatccgaacc ggaaaaagag
    45481 cacgcctttc caatggcgat ggaatatcat ctttatctcc gtattcttat gcgtggcgga
    45541 ttgggtgtac ttttatgcct tgacattccc ggattctatg atctcgatcg tatcgatggt
    45601 acgtcggagt aacgtattgg tgacattctt ggcgggagcc atcttcttcc atgaaaaaaa
    45661 cttaaagaac aaggcgatcg acttattcct tgtgttgtta ggaatgatat tcctatattt
    45721 ggggacaaaa tagaaaatta gataatgaga cgagttatag ttacgttgtt gatctgtgtc
    45781 tttgcgttgg gaatgaacgc acaagatatg acaagtgtgt tcacggcaat gccagaccaa
    45841 tacattcctc aattggagca cgcttggcga aaggatttgg tggatcttta tacttcagga
    45901 aaagaatccc ggctgaaaaa tacgatgaat ggcttttcta ccttgcaaaa gctaacgaac
    45961 gattaccttt tgctacagac tacggagcgt agcacggtag agatgaaatt acttcccttg
    46021 gtaaacaata cctacgtggt ttgtatgatc tctacggtaa acggcccggt tccggatagc
    46081 cgtatcgagt ttttcacgac caattgggag cctttggcaa catccgattt attcacgcag
    46141 ccaacttccg attggtatat caagcaggga atagataaga aagacgaagc ctatcaagag
    46201 gccgcctcac atttggatat ggatttaatt caatatcgat tgagtccgga tgatcagact
    46261 ttgactgcca tttatacgac tcctcaatat ctgagccaag aggctcgtga gaaaatagag
    46321 ccgtatctca ttgaaccgaa agtctatacg tggcagaaat atcattttca gtaattcttt
    46381 ccttatccat ccactccgat atagttcaag aggttttttt gcggtactac tgcacggcgg
    46441 ttgcggcaat actgcacgtg ggttgcagta gtactgcgat aaagagtctt tttttaatgg
    46501 gtaggagaga ctaagatccc ttcttcatta aaaagaattg ttatatctcg gtctccttgc
    46561 tccagctcga actcataaga gagtccttcc gctttttgaa tgacatggat atcatcgatt
    46621 tgataagagg catatgcgga ggccttgaat gcggtcatca cgatatcggg tacttgggaa
    46681 gagcgtattt cccactccgt atataaccat ttgttctggg tatccagcca aacttcctta
    46741 tggatattct catgaaggat atccacctcg gtaccttttg tctccgtatc tatctcaagg
    46801 attgtcgctc ccggatacat ctctgaaatg agttccttaa tagcgctggg ggtaacagag
    46861 ggacgatgct cgttgtcgcc gttaccatcg gttacttcct tgatgagaat accaccttcc
    46921 gtataatgta ggtctgcatc ttgctcgcca ttttcaacgt cgagaacgta aatggtacca
    46981 gcgtccggac gttctagcat atctacatcg tctatcttcc atttagcgta taggcttgcc
    47041 tcgaaactgt tttttacggt ttggggcaaa gcgttgtaag gaagatcggt ctctgtcagc
    47101 atccagttgc cttgcggatc aaaccacgct tcagcctcat atgaaccggt gtaaaattct
    47161 gctttgacat agcctgcctc gttctcccaa ctgacacgtt gcgcatccgg atattttgtg
    47221 tcaaaggctt ttgttacaat actctcaggt gtgaatttgt catcatcgtc atcacatgac
    47281 atgaatacga atgagctgca aaccaaagtt gccattatga atgcttttgt tttcatacga
    47341 ttgattttaa ttaaaaatat attaatactt atcttagagt gtctattagt catcgatatc
    47401 aatcaagttc ccttttaagt cgaatgtcat ctcaagaccg ttatctagct ttatctcata
    47461 atcccgtatc tctttttcta ttttaacaac cttattcgat gaatagtttt tcttgataag
    47521 gtcttgtatt acctccggaa tgatcgctgg cgggataggg agcccatgcc gtttaatctc
    47581 tttccattct cctttatggt taaactcaac attggtcccg tccgtgagga tcacgtcgta
    47641 actgctaatc cggatcagat ttttctctat ttggatatgc gatactggga tgtctttaaa
    47701 atgatccgat atgaattggc ggctggaaac cggcaatatg ttggtgtcac tcgtgatctt
    47761 atcattgccg gcacaagcca tgacagataa taatgataag actatcagta aataattgat
    47821 ccttttcata tgccttgttt tttattatac cgcaaagaaa aggatgcatt ttggaaaaaa
    47881 ttgggaattt cggccgttaa tagaataata atgtgaatgt atgcatgcca tttgcgtatt
    47941 ggtaatctat ccggatcgaa tatagatcga ctattgattt gacaatggcc aacccaaggc
    48001 ccgtcgattc ttgttgtttg ctttggctgg caaaacgggc aaataataat tccttatcaa
    48061 gggttttgtc gattcccgta tttgcgattg taagcatacg acgagagatc gtgattccta
    48121 tatccccttt ctcgtaatta tggacatagg cgtttttaat gagattggtg attaacgtag
    48181 tggccagcga ttcattcatg gtgcatacca aactctcttt ttctgaaact cgtaagtgga
    48241 gagcttttct ttcgtatatg tcattaattc cttctaatat cttatggata agatgattta
    48301 ggcaaatatc ccgggtctcg gggaattgtt tgttatctat ccgagaaagt aataggaggg
    48361 atttattcaa ccggatgatg ccgttcaacg cttgatgcaa gccagcgatc tctttcagtt
    48421 gatcttctgt gcaatctgga tgttcgctta ataattctaa tttgttcatg catacggcca
    48481 atggagtttg taactcgtgg gcggcattct ctacgaaatg tctttgtttg ttgtatagct
    48541 tgtcgctctg gttgacgctt tcttgaacgg tctcgtttaa tatcttaaat tcctcgatgg
    48601 gtgtagggtt gtttaatgga ggattatatt tgcctacttg aaaacttttc agccagctta
    48661 atagcttata taaaggctta aagcttcttt tgaatcctcg atggatcacg aataagatgc
    48721 aacttatcaa tgcgatatat aagacggcca tgctccagat aatcgtctcg atcatatctt
    48781 cttgttctaa ggtggataac tccagcgtca gttcgtagaa tttacgatct tttgtcatga
    48841 aataagtgcg taaggcacga accggttcgt attcttgctc tatctctatg tataccgtag
    48901 tatcgtagaa ctcgtcctta tctagtttcg cttcgctttc cggaacctca cgaatgtagt
    48961 accgggtcat gatatccaca tgatctttca gcaatgtgct gtccgctaag gcggagcgga
    49021 tgataatctc tttgtagttc tcaaggctgt catttgtctc gtcttctacc tcatgtagaa
    49081 tcataaggca gaaaacacat ccccaagcgg cgaaaatgac caatatgggg acaaataaat
    49141 tgcggagggt gtaatggatt agcttcatat ttattcctcg tcggtcattt tgtaaccgaa
    49201 gccatagacc gcctttattt cggggatggc tccggcggct tttaatttct ttcgcaagtt
    49261 ttttacttgg ctatagatga agtcgaaatt atcggcttgg tctatataat ctccccagac
    49321 ggactcggct aaagtagctt tgctgatcaa acggttgggg ttggatatga aatagtagag
    49381 cagatcgaac tccttacggt tcaatacgat ctctttcccg tttatataga cggaatgttt
    49441 atcgggatat atcgttaggt tcgctaaaga cagttgcaat tccccatctt gttgcttgcg
    49501 gcggataacg ctcttgatgc gggcgttcaa ttccgccaga tggaaaggct tggtcagata
    49561 atcatcggcc ccaagatcta atcctgtaac tttatcctcg atagagtctt ttgcggagat
    49621 aatgatgata ctgtctttct tgcgtaaggc ccttaattcc ttcaaaaggg taaggccgct
    49681 acctcccgga agcatgatgt ccaatacgat acaatcgtaa tcataatcat ttattttaag
    49741 agaagcttcc cggaaagagg aagcgctctc taccacatat cgttcttttt caagagaacg
    49801 aacgataact tctctcagtg cgttttcatc ttcgactacc agaattttca taggctagct
    49861 tgttaatcac acaaagctac tgaaatattc tgataaaaat ctggaataag aaaagattca
    49921 gtatcgttct acttcaataa ttgggcctct gagttaaacg tgagacgaac ctcattgttc
    49981 tcatgctcta gtttgaatac gtaaaatgtt cccgaaggct tgtctatttg tgtcacctca
    50041 tctatcttat attcatgata agccgaattt gttaggttat ccatgatgtc tacgggaaca
    50101 tcttcggcat ggatatcgaa tttcgtactt agccactcgt tatttttgcc gagcagaacc
    50161 tctttcttaa cgcctttatc cttgatgtcg acttctacac ctgcggcatc tttatcgtaa
    50221 tcggtaatgg tcgcccccgg atattttatc tggatcacct tttgaatcgc ttgagagacc
    50281 gatttgtcat cgaaaccttg tttcttttgt tggcaaccta cggtgaggaa taagcagctg
    50341 ctcatgaata aaatggctgt aaatgatact tttagtttca taacgtttaa gttttctatt
    50401 acaaacaaac gggtgacagg caaagttttt tccaaataag ttaattttcc atgatatgtt
    50461 tttcttcctt tgtcgtcttg attatagaaa tggaacttga gacgtttaaa ataaccgtac
    50521 tacctctccg gcagaagatg ttgaatttct cccggagact ggttgaggac gcagccgatg
    50581 ctgaggatgt ggtgcaagag gcattcataa agctttggta tatccgggaa aaactggatg
    50641 cctaccatag cgtggaggcg ctggctatgc aggttacgaa aaatctctca ttggataaga
    50701 taaagttgcg aaagccgcag ggatcggagt tggagagcgt tacattgata tcggaagcgg
    50761 taagcccgga cgaacaactg gagcaaaagg atgccgccga gtgcatacgg cgcttgatcg
    50821 cccagttgcc cactttgcag caaaccatta tccggatgaa ggatatagaa ggctatgagt
    50881 tagccgagat cgcggagatc acggctacac cggtcgagaa tgtccgggtg aatctctcaa
    50941 gggctcggaa aaagatacgg gaacagtttt tacaattaaa taaacaagag aaatggacat
    51001 agacgagtta ttaaaccgat attttgaagg agaaacctct tcggaagaag agcgggaact
    51061 tcgagccttc tttacttccg ggaatgttcc ggacaggttg gcggtctata cgcctatgtt
    51121 tacctatttg gaggaagaga gtcggaagga acgacagcca gatgaggcat tgattccgat
    51181 tgatgaggat atccttttta tgctggatgc ggaaaaggtg gaggaaaaga agacatttac
    51241 tttacgatcc gtgttgtatt tggtatccgg tatcgccgcc agtttcttgc tgcttttggg
    51301 gcttaaccat ctgttgaatc cggtagatcc ttgcttctgc tcggataatt atgtcgttat
    51361 aaacggtcgt tgttatacgg atattcataa agttcgctcc atggcgctgg aagctttgca
    51421 ggaggtggcc actcctacgg acgagtactt cccggaagtg gatcttgatg aggccgatcg
    51481 tgtgattata gataaccaat tggacgagct tcgttcttta tttgatgata atgaataaaa
    51541 atactgtaaa tatgagacgg ttcaaataca tgttatggtt gctggtggcg gtattttgct
    51601 taatgccttg tggtgtctcg gctgccgaga cacagaaaga tttgaagatt caggaagtct
    51661 ttcaacgata tggcaaaaaa cgtaatgtca cgatggtgga gttgtctaac gagatgttgg
    51721 aaacgtatgg catgactcgt tataagagta ttacgatcaa agatgatccg gaagccctgc
    51781 ggtttacccg ccaatgtctg gaagcggacc agaaaggggc ccggaagatc aaagaggtga
    51841 cggacgatgg aggggtagtc tccgcttatt accagttgaa gggcgtagaa gcagatatca
    51901 accgttttgt cctttttaag gtcagcaaga aaggggtaat aaccttggtg tacattgagg
    51961 gagatttgga tagtgatgat ttaatcacgc tattatttac gaagaaagat ttataaacaa
    52021 acaaaacaga taggaagatg aaaagaatac ttttagtctt aatggcttgc ttcccggtaa
    52081 tcgggttgat ggccgctgag gttgagcctt tggctgggga tacgattatc acccttgaga
    52141 gaaaacgtat cgaggtgaaa gataatggcg atcgcatgaa agtcagggtg tatgaggtag
    52201 acgaggatgg tgattccgtg gacgacgagt tgatcttcga agggcattac cgggacggac
    52261 aaagctatga acgccgtaaa cacgtgaagt ctatcaatat ccctgtgcct acttgggata
    52321 aagacttcaa tccgcattgg gccggttttg gaatgggctt cgcgaacttt gcggatggga
    52381 gtttacatgt aaatgatgta gacggagtct cccttcgtag tggaaactca ttggaatata
    52441 atttgaatgt attggaaaaa gcgttcccgt tctctcggta tcgttgggcg gtggtgatcg
    52501 gtgccggtat gcgttggagc cgttaccgga tagatacgaa tgagtatttc aaggagatag
    52561 acggtgttac ggctttacgt ccggctcctg agagtgttac gttgaaagcg agtaagctga
    52621 atatcacgag tctgaccatt ccgttgttat tggaatggca acctaaaaag cgttcgagtg
    52681 aattcttctt gtctgcgggt gtagtcggtg tgatcaagac ttgttcttcc tcgaagatcg
    52741 tatataatga cgcttccggt aa
//
LOCUS       DBMDTB010000014        52157 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_268_length_52157_cov_12.230483, whole genome shotgun sequence.
ACCESSION   DBMDTB010000014 DBMDTB010000000
VERSION     DBMDTB010000014.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 52157)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 52157)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52157
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_268_length_52157_cov_12.230483"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..626)
                     /locus_tag="ACZPB4_04090"
     CDS             complement(<1..626)
                     /locus_tag="ACZPB4_04090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HIR1097434.1"
                     /translation="MPEFITIEEAARITGFPSEEIQQWAISKKIASYVVKQGVRLVDL
                     TNLREFISHIERMGIQKLYLQLIIQDKEEEINEIISQFDDYLFCLRSLKNISPLLKLI
                     IAELSTFIHDKKDRLIFTEITSGAKIEDVAKRCGISYDGICRRYKVISLRLQENMGFL
                     TEYKKTITNQDLDIERLWIENRNMEYELRRLYKKALQNGLCIESPRSLT"
     gene            complement(1224..2345)
                     /locus_tag="ACZPB4_04095"
     CDS             complement(1224..2345)
                     /locus_tag="ACZPB4_04095"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097435.1"
                     /translation="MLFLGGSQTFIGILASLIVLCVILDKSNFIHSILDEIGKRIDEE
                     IKSLDKAVGFDVINDVPANSDYKLLQRYINELRVEAKTRPECKQLLISAMAMDMKLQA
                     TFDQLKSGYSSKFLKPAHDLIEKIQRSKEQVIAPLYALLFCLTVFICDEIVVGVAGTS
                     DFVVSFLTIFVAFSGIFWLMMWKIFFRDIRIETEEGSSQKTKVFVSRWIRWKWMCFAF
                     PMFYATCLFLSTFIPIIWAKCLISFTIGIPICVMAWLKAKSHYEFGFYTYEYVFKHFG
                     GLFLISFLFAVVTTGGCALSDDVSSVCFTYEDFVALKITVILFVLISGLLFPFLMPYY
                     GFKRVLNIVKDEVKSSKQSMERELSSIKEELKEFCKVIP"
     gene            complement(2358..2963)
                     /locus_tag="ACZPB4_04100"
     CDS             complement(2358..2963)
                     /locus_tag="ACZPB4_04100"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097436.1"
                     /translation="MRLEDLNEYYDNLCDTFDRGEMDFVMNHDRAHNAVIECFMLNKS
                     NVINMYCGEMSVFREGFYNHINQDSNYDLKEGETALGDEIKKKVIKSLREFINRPNVS
                     LNIYFERFDRKFLRDLIDLRVFSDGVSSEKIRLFKLEDNLFLKSDMAHVSYTDTNIVR
                     MERNPQTHEATCAINPPEEILSKVKATFKSMSLVGEEIKLN"
     gene            complement(3527..4477)
                     /locus_tag="ACZPB4_04105"
     CDS             complement(3527..4477)
                     /locus_tag="ACZPB4_04105"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004314092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004601 - peroxidase activity [Evidence
                     IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Dyp-type peroxidase"
                     /protein_id="HIR1097437.1"
                     /translation="MNSLQNPLNANYPQDVTQKPGENAVFIVYALKDLPDTIDKVKDV
                     CANFSALIRSMRNRYPDMQFSCTIGFGADAWKRFFPEQGNPKELQPFEEIKGVKLTAV
                     STPGDLLFHIRCKQMGLCFEFASIIDQKLRGVVESIDETHGFRYRDGKAIIGFVDGTE
                     NPAVDEDPYRFAVIGDEDPEFMGGSYVFVQKYIHDMVAWNALPVEEQEKVIGRRKFND
                     VELSDEEKPKNAHNAVTNIGDDLKIVRANMPFAHTSKGEYGTYFIAYASTFSTTRRML
                     ENMFVGDPVGNTDRLLDFSTPITGTLFFVPSYELLDKLGE"
     gene            complement(4626..6824)
                     /locus_tag="ACZPB4_04110"
     CDS             complement(4626..6824)
                     /locus_tag="ACZPB4_04110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 3 C-terminal
                     domain-containing protein"
                     /protein_id="HIR1097438.1"
                     /translation="MKKIIGVIACGLFLNAAAASSQVTDKEKVQMEKRIEKLIKKMTL
                     EEKVGLLHGNSKFYVAGVERLGIPEWSLSDGPHGVRAEINRHDWAYAGWTNDSASYFP
                     TGTAFAAAWNPELAYRRGEVLGEEARWRKKDVLLGPGVNIIRSPLCGRNFEYMSEDPY
                     MNSVLAVAYIKGLQSRDVACSVKHFAVNNQETNRTTIDVECSERALREIYLPAFKAAV
                     QEGGALTVMAAYNKFRGEFCAENNYLVRKILRNEWGFDGVYVTDWGAAHSTVPSMEAG
                     LDLEMGTLIDKYEDWYYANPLIEAVKSGKVPMSLVDEKVGDVLRVMIKTNVLDPKKRF
                     GPGSMNTKEHQQATYDAAAEAIVLLKNQNNLLPLDFSSIKSLAVIGDNATRKHSNGGL
                     SSEIKAVYEVTPLEALRAKWGDKVDIRFAQGYEKLSTFVEGSNNGQSSGTFSSKTQES
                     DALLKEAVEVARTSDVALLVCGLNHDYDTESFDRLNMDIPYGQVELIQEVVKANPRTI
                     VIMIAGSPLNMAAVDICSPAIVWAWFNGMEGGNALVDVLSGKVNPSGKMPFTTPVSLD
                     QSPAHALGNFPGRDLKVNYEEDILVGYRWFDTKGLPVVYPFGYGLSYTTFNYSNLNTD
                     KKTYDQADTIQATFTLTNTGDREGAEVAQLYVSDPVCSVMRPVKELKGFKKVFLKPGE
                     SRRITLDIPVSSLAFYSEAQSQFVVEPGEFILQLGASASDITQRISVEVK"
     gene            complement(6847..>9293)
                     /locus_tag="ACZPB4_04115"
     CDS             complement(6847..>9293)
                     /locus_tag="ACZPB4_04115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="sugar-binding domain-containing protein"
                     /protein_id="HIR1097439.1"
                     /translation="WNDDWKFALSDSVQDYSSPDSDDSTWRILSLPHDWSIEGDFSLD
                     NPSTPGGGALPGGIGWYRKTFTLPETDRGKVVYVDFDGVYRNSEVWINGHSLGFRPNG
                     YVSFRYDLTPYLRYGSQPNVIVVKADNSEQPNSRWYSGSGIYRNVWLVKVNPVHVDNW
                     GTFVHDMRISPEEATFSLEVRIRNSSEADRDAEISTSIYDDRNRVVTAPVTTLLRVPY
                     TPCYDARMREASVDHQFSIPNPKLWSPDSPSLYTAVTEVKVAGKVVDRYETVFGLRSF
                     RWDSATGFYLNDKPLKIKGVCLHHDLGCLGAAVNTRAIERQLQIMKEMGVNAIRTSHN
                     APAPELLDLCDRMGLLVQDESFDMWERRKSPYDYARYFAEWHERDLTDEILRDRNHAS
                     VFMWSIGNEVLEQWSHADATELDLQAANLILNAGHAIDPALLKDTTLSRQSLITRHLA
                     AIVKRLDTSRVVTAGCNEVNPANHLFRSDALDVLGFNYHERYFEPFLRNFPGKKLIVS
                     ESTSALMTRGYYEMPSDHIYIRPESWDKPFEAPEHVCSSYDNCHVPWGSTHEKTWHLV
                     KTLPHVSGLFVWTGFDYLGEPTPYWWPSRSSFFGIVDLAGFPKDVYYMYKSEWTDEPV
                     LHIFPHWNWKEGEPVDIWAYYNNADEVELYLNGKSLGVRQKTDSTYHVSWRMPFTPGT
                     LRAVSRLGGKEVLVKEIHTAGEPARLVLTPDRSVIQADGSDLSFVTVDVCDIDGNRVP
                     DATPLIRFSVEGPGEIAGTDNGDPNDPNSLRKPKRQAYYGKALVVIRNKGGQGDIHLK
                     AIAEGLPEATVTIQAQ"
     assembly_gap    9294..9393
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<9394..9576)
                     /locus_tag="ACZPB4_04120"
     CDS             complement(<9394..9576)
                     /locus_tag="ACZPB4_04120"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097440.1"
                     /translation="MNRPLAWLLGLLLTACSPTGEQVRERSPWNDDWKFALSDSVQDY
                     SSPDSDDSTWRILSLPH"
     gene            complement(9684..12530)
                     /locus_tag="ACZPB4_04125"
     CDS             complement(9684..12530)
                     /locus_tag="ACZPB4_04125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIM-barrel domain-containing protein"
                     /protein_id="HIR1097441.1"
                     /translation="MKQHIAVFTLGLSLLTSCMTDSAYRKVENGLVADIRSGQAKAVK
                     LEVISDDIIRVIASPDGKFSNQVNLIKDTKSLPAPSFQITTSGDTIIVSTQTTQARLS
                     RETGEVRFTDANGHTILREKTNGGKEFTPIEVEGTKGYTLRQVFESEDEEGLYGLGQH
                     QSDEFNYKGKNEELFQYNTKVSVPFIVSSKGYGVLWHNYSLSRFGDKRPYADLGDVFG
                     LYGKDGRAGALTATYYTDKAKNSVLIQRDEDKVDYENLKTIKNLPADFPKPSASATWE
                     GEIEAKETGTYHFKLHYAGYTKVFVNNEEIIPERWRAAWNPNDYKATADLEKGKRYPI
                     RIEWLPDGDVSYIGLKVLSPLPEEERERLAFWSEMGDDIDYYFINGESSMDKVISGYR
                     TVTGKSQIMPKWAMGFWLSRERYKTQEELLTALNEYRRRQVPLDVIVQDWSYWPVDAW
                     GSHEFDKERFPDPKGMIQEIHDKDARIMISVWPKFYYTTEHYKELDALGAMYQQAIKD
                     SIRDWIYPGYIGSFYDAYNPEARKLFWEQMNEHLYSLGIDAWWMDASEPNVQDNTDIE
                     YRKALCGPTYLGPSTKYFNAYALANAEAIYDGQRSVNPDDRVFLLTRSGFAGQQRYST
                     ATWSGDIGTRWEDMKAQISAGLNFAMSGIPYWTMDIGGFSVENRYMAAKEGSEDLREW
                     RELNNRWYQFGAFCPLFRSHGQYPCREIYNIAPEGSPTYQSMKYYTELRYQLMPYIYS
                     LASKTHFEDYTIMRALVMDYSDDEKTYDIDDQFMFGPAFMACPVYEYKARDREVYFPS
                     GIWYDYYNGKRIQGGTTMHVDAPYERMPLFVRAGSIVPNGKVIQSTKEEQKDLIVSVY
                     AGADGSFTLYEDNGVTYDYEKGNYATIPFVYDDARRTLTIGAREGDYPGMIRERQITV
                     RLITPENPAGKDVTISYQGKPLVVETGRAPSQPL"
     gene            complement(12761..16840)
                     /locus_tag="ACZPB4_04130"
     CDS             complement(12761..16840)
                     /locus_tag="ACZPB4_04130"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hybrid sensor histidine kinase/response
                     regulator"
                     /protein_id="HIR1097442.1"
                     /translation="MILSWGILGSGLAAEDILFNRLGVQDGLSSNEITCILKDRKGFM
                     WLGTTSGVNRFDGYEFKHYKYKESGLPFREEHVSELQETADGRIWITYNTNQLCVYEP
                     GNDRFIPEKEILDSLRLENPPAKIFVDNDKQLYFATYTNEFCRYDQARGKIYSYPLNK
                     EDGRVCDMSDVGDRLYVVHTSGVVEGIDKASGESVYRDEYLTQYANAQLFYVFADSDG
                     DLWFFLNPGYSRGLFRLNPKSKEWKHYTTETSVALSSIMVRDVAEDMNGNIWIATDHG
                     GINILDKRLNRMRYIRNNPFNQTSLSQNSVICLYRDDTGIMWAGTYKNGINYYHESIF
                     KFQTIRYPLELMRDIFNNDFNCIVEDKEGDLWIGTSGNGLLRYDRETGEYVRYRAGRE
                     SENAISGDVVISMAKDLDGKLWLGTYMEGLTGFDGKRFKHYRDIPGSKDGLSNNSVYS
                     LYVDAKNRLWIGTLEGGLDCLDQSTGKWTYYRMGDKENAINSDIVYSLSGDEKGNIVV
                     GTSLGVNWINPETGAVTSFNGTKDGRSVFEDQIINVVFCDSRQWVWIGSNYGLHIYDR
                     LNDKMYRLNHSSGLPDNSIMSILEDKYHTVWVGTKNGLLNIVPNRDTDNNYTFDWNSY
                     DENEGVQGRVFNVNSACGLETGELAFGGTNGLTFVDPARIRYNSYAPPAVITGLMVNN
                     VPITAREAYDGHVILDKDITCTKQLKLNYTERNFSFTISSCCYFLPLKNKYAVKMEGF
                     DSEWTTVSALERRITYTNLNPGTYTFKVKAMNNDRIWSKEITSLQITILPPFWATGWA
                     IALYIIAGILLAYGVIRFIFRIQQKKLEEEQERATVRQQHEVDEMKLRFFTNVSHEFR
                     TPLTLIMTPLEKLMKTEKDLESQQILKLIYRNADRLLKLVNQLLDFRKIDMQGDSLVL
                     STGDIVPFVRDVAYSFKELSEQKRIHFSFSSVFTSLPMKFDTDKVFKIVSNLLSNAFK
                     FTPEGGTISVTLSLRLEKEGENKLVIEVSDSGIGIPADKQGAIFDRFYQVASPDKGNP
                     VVGTGIGLHLCREFVRMHHGTITVKSEPGAGSTFTVTLPVIPLDNQDIISAPEGIAEG
                     DILPPVEEHAEIADKDASPAGRPTLLVVDDNTDFREFMKLSLSGVYSVLTAADGEDAW
                     KLIPEELPDMVISDVMMPITDGITLCRRIKGDIRTSHIPVILLTAKSAKDSQLVGLEA
                     GADDYISKPFNMEMLLLKVRHLIEMKKKMQKAFMQSSTMGIALTEVQASSMDEELMRK
                     AIAYIEEQIANPELSVERLSREMGMSRVNFYKKCLSITGKTPVELIRTVRLKRAAQLL
                     EKSQMRVNEVALECGFNDVKLFRKYFKDEFGRLPSDYHK"
     gene            17044..17964
                     /gene="ribF"
                     /locus_tag="ACZPB4_04135"
     CDS             17044..17964
                     /gene="ribF"
                     /locus_tag="ACZPB4_04135"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003919 - FMN adenylyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006747 - FAD biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009398 - FMN biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HIR1097443.1"
                     /translation="MIVVRDFDRLKGKELVATIGFFDGVHLGHRFLIDEMKEIAKARN
                     LPSAVITFPEHPRAVLHADYQPKLLNSFEEKLQQLETTGVDYCIVLDFTIELSRFSAK
                     EFITSILAKSLHVKTLLIGYDHRFGHDRTDGFEQYVVYGTECGIEVLKASPYDEGNTA
                     VSSSEIRKLLQAGNVAEAAYLLTYPYQLLGHIVSGYKVGRTLGFPTANIRVDEPFKVI
                     PGIGVYAVWVEVEGERYKGMLYIGDRPTLNNGKDISMEVNILDFSGDIYNDSIRVSFV
                     QYVRGDIKFDSLEELKAQLEKDRCTVNNLL"
     gene            17966..19021
                     /locus_tag="ACZPB4_04140"
     CDS             17966..19021
                     /locus_tag="ACZPB4_04140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallo-hydrolase"
                     /protein_id="HIR1097444.1"
                     /translation="MERYYEAIDLLKGMISRPSFSRDETAVADFLQAEWQKAGQKVFR
                     KGNNLWIIAPDFDFGKPTLLLNSHIDTVKPASGWTKDPFTPEETEDDQLYGLGSNDAG
                     ASVVSLYEAFCILSEKEQPYNLIFLASCEEEVSGKNGIESALAELPPISFAVVGEPTG
                     MQPAVAEKGLMVLDCTAIGKAGHAARNEGINAITLAMKDIEWFSTYQFPEKSDFLGPV
                     KMTVTIIHAGTQHNVVPDKCEFTVDIRTNEFYTNEQLFELIKEKVHCEIKARSFRLSS
                     TRTDLDHPFVRRAILMGKEPFGSPTLSDQALMRFPSVKIGPGNSARSHSADEYIKGPE
                     IREAIDTYVRLLNGLQL"
     gene            19025..20299
                     /locus_tag="ACZPB4_04145"
     CDS             19025..20299
                     /locus_tag="ACZPB4_04145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0140327 - flippase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HIR1097445.1"
                     /translation="MLKKILGTIGSRYLIAFLNLALIFINAKVLGIEGVGMIGLIVAS
                     VNIAVIVNGILCGNTIVYFMNRYSMRTIFLPAYLWTPIGSSLACGFMYLTGLLPTGYR
                     LDIFLLAILSSTVNANARFLLGKDNIKGFNLTFILQGGLLFFVLLYFYYILKRPDVRS
                     YVWGLYVTNGIAFIASLSMLVPYFLKETSRSSGKSLYGLLKEMFAYGLWAGADGLAET
                     CTTRLNYFLIQRFAGLGSVGLLDAGTKISESVWNISRSVSFIEYSSVAKTSEATEQKR
                     ITLQLFKLTFCALALVMGCILLVPEWIYTDYLFSAEFKGIRKVIGGLSIGIVALGCNS
                     IISHYFIGSGKIRYSTASSCVGLIALLISGFLLIPSYGVVGSAITTSIAFTSMLVFSL
                     TVFSRQTLTRWNEFLPNKKDFQACRIHIQKSL"
     gene            complement(20396..20845)
                     /locus_tag="ACZPB4_04150"
     CDS             complement(20396..20845)
                     /locus_tag="ACZPB4_04150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YqaA family protein"
                     /protein_id="HIR1097446.1"
                     /translation="MEFLIAYGYIGVFIASFLAATILPFSSEVVLTGVLLAGSAYWPC
                     MIAATLGNFLGGMSCYWLGMLGKVEWIEKYLKLDPVKLQKVQDWIKGKGSWMGFFVFL
                     PGIGDFIAVALGFLRANIWVVAISMFLGKAIRYWVWMEFVYKVQSMF"
     gene            complement(20830..21846)
                     /locus_tag="ACZPB4_04155"
     CDS             complement(20830..21846)
                     /locus_tag="ACZPB4_04155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097447.1"
                     /translation="MARGTTSYYGRRYTIATPMTHLYMLCACIFCWIVGYVDSVGYPV
                     YGEVTAPPLWNALCLVLPGKLFTYLIGFLLMAGGAFLVHRVNYALMLIREKTLLPFLF
                     YALLTSTNPDFFPLKSTSVGVFCLILALYQLFTSYHDPDATDKAYNASLIISIGSLLW
                     IHILWFLPLFWLGMYNFRTLNIRTFVASLFGILTVYWFVFGWCVWERDFTAFTIPFTS
                     LFKIRFLAVLGTGIIDWIQIVLVAGLTIIASLNIVTHEYEDNLRTRQFLSFLIVMAIW
                     SFGLFFIYEQSSEEFLEMACVPASILIAHFFTVNRGKYIFWLFHLSVAMFIALLMIRI
                     WNFL"
     gene            complement(21989..23260)
                     /gene="purD"
                     /locus_tag="ACZPB4_04160"
     CDS             complement(21989..23260)
                     /gene="purD"
                     /locus_tag="ACZPB4_04160"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HIR1097448.1"
                     /translation="MNILLLGSGGREHAIAWKIAQSPKVDKLFIAPGNAGTALVGTNV
                     DIKADDFAAIKDFALANQVNMVVVGPEDPLVKGVYDYFKKDEALSSIPVIGPSGEGAQ
                     LEGSKDFAKAFMMRHHIPTARYKSISTENLEEGYAFLESLSAPYVLKADGLAAGKGVL
                     IIDNLEEAKKELGDMLGGMFGDASKTVVIEEFLDGIECSVFVLTDGNDYKVLPVAKDY
                     KRIGEGNTGLNTGGMGAVSPVPFADEAFMAKVDERIIRPTVEGLKAEYIDYKGFIFLG
                     LINVKNEPMVIEYNCRMGDPETEVVMLRIQSDLVDLLEGVAEGDLAARTLVQDPRAAV
                     TVMLVSGGYPEAYEKNKVITGLDGVSSNNIVFHAGTKLVDGQILTNGGRVIAVSSYGA
                     TKEEALAQSFAGAKQIDFDKKYFRRDIGFDL"
     gene            complement(23296..25497)
                     /locus_tag="ACZPB4_04165"
     CDS             complement(23296..25497)
                     /locus_tag="ACZPB4_04165"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HIR1097449.1"
                     /translation="MMIMRIKSSLFISLCLILLTMSITAQDKQLSLHDLIPGGKTYSR
                     FVPRDLKQLRWCGDEYLYVKGDSVLGAKPGKKEEVLFSLERLNGALTAANLQTVGSLP
                     SFSVPYERGSVLTFTSKQHRIHYDYKKNKVVADYALKNNWANYDFCPATNNLAFTEGN
                     NVHILSPDGRNTIVTRETQDGIVCGQAVHQREFGITKGMFWSPKGSALAFYRMDKRMV
                     TAYPLVNIDTRCATPVPHKYPMAGMKSHEVTVGVYQVATGQTVWLETGLPKEKYLTNI
                     AWSPDEKSIYIAELNREQNEMHLVRYSALTGKKEADLFTETDRCYVEPQHPVLFLPND
                     PDKFIWQSEADGYNHLYLYDTTGKELRKLTGGEWVVTKVLGFSKDGNKVIFEGTAPHP
                     VSPNMQGTGMQRYIWETDLRTGDIMNCLSWKVGVHRWLLSPSGEYAIDYVSSPSTPRD
                     IDLVRIKDAKVISTLLSAPDPFKLYRMPRIKVGHILAADGKTRLNYRLTLPPDLDETK
                     KYPTIVYVYGGPKVQLVTGDWQNGARGWDLYMAQRGYVMFTVDSRGSANRGHAFESVI
                     HRNLGINEMADQVKGVEFLKSLPYVDADRIGVHGWSYGGFMTTNLMLTYPEIFKVGVA
                     GGPVIDWSNYEIMYGERYMDRPQDNPEGYKNANLKLKAGNLKGHLLMIHGDIDPVVVW
                     QHSLGFLKACVEADTYPDYFVYPRHEHNVTGKDRPHLHEKITRYFDDYLGN"
     gene            complement(25478..27028)
                     /locus_tag="ACZPB4_04170"
     CDS             complement(25478..27028)
                     /locus_tag="ACZPB4_04170"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="THUMP domain-containing class I SAM-dependent
                     RNA methyltransferase"
                     /protein_id="HIR1097450.1"
                     /translation="MSETFEMVAKTLYGLEEILAEELLALGANDLQIGRRMVSFTGDK
                     ELLYKANFHCRTALRILKPIYHFKAKDADTVYKEVKKVEWEKYLSLDKTFAIDSVIYS
                     EDFNHSKFVAYRTKDAIVDYFIEKFKKRPSVRVNNPDLYINIHISHNDCTLSIDSSGE
                     SLHKRGYRVDQTEAPLNEVLAAGMILKTGWKGESNFVDPMCGSGTLLIEAAMIALNIA
                     PGIHRKEFAFQKWVDYDEELFDRIYNDESGEREFAFHCYGSDISQAAIDIALENIRSA
                     GLMKYIDLKVKPFQQYTEAPKPGILVTNPPYGERISSRDLLGLYNMIGERLKHVFMGY
                     KAWILSYKDECFDKIGLRPSEKIKLMNGSLECEYRCYELFEGTNKDFKKALNEDGEER
                     PHRSEGSFERRGNDRPNFRTGRVDRPERRFAAAHSEDDEERFASIPGKRIFGEDRGED
                     RPVRKKFVDAPVRKPIKPKGERPVKMRYRDEDDRKKGFGDHKRDGKRPFSKPIKPIKR
                     RGYDDYED"
     gene            complement(27159..28058)
                     /locus_tag="ACZPB4_04175"
     CDS             complement(27159..28058)
                     /locus_tag="ACZPB4_04175"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HIR1097451.1"
                     /translation="MDIQRHSSVLGDTVEKLSDEASYKQLFHAYRDEEALPSGEVLKE
                     IIDLCRAILFPGYYGNARISKQTIRFHTGVNVETLHSLLSKQVYAGLCFADTSCVTCP
                     EEKISAEAEAISEAFISTLPEIRGLLATDVEATFNGDPAAQNLGEVIFCYPGFRAIGN
                     YRIAHQLYKLGVPYIPRMITEMAHSETGIDIHPGAKIGHHFSIDHGTGTVIGETSVIG
                     NYVRIFQGVSLAGEKLPPDENGNAIRGVARHPILEDHVTVYSNSTLIGKIRIGRGATI
                     CGNVWIAEDVPAGSTVTQLKIEN"
     gene            complement(28235..29230)
                     /locus_tag="ACZPB4_04180"
     CDS             complement(28235..29230)
                     /locus_tag="ACZPB4_04180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097452.1"
                     /translation="MRVLYGIIVFFALFLLACSDAEREEKRLEGNLLMKGDSGVCYDG
                     IGLTESYLVLLARGCDTIIQVFDKDDLSHLHAFALKGYGATYFSNPEFMKSNTKEPAG
                     KDEFWIVDNQLTFNKMQVLADSLRFDRKYILIPELVPSTHYNVTTKEVYAVPIVEKNV
                     YGPFCYANREEGIYWVEPPKVARTYRSCKHVAYLPNLCVNERQNSVVAALRFFNQIDF
                     YDLKGTYQRSFTYGKEPIVPLLKKNDTQVDVLGTTKCFIDIFGTDRYVYCLYDGSVDF
                     SNLSTLLVLSWDGQLKKRLNFDRSIKRIAVDPSDGFLVALALDESGALDVVKYSI"
     gene            complement(29227..30363)
                     /locus_tag="ACZPB4_04185"
     CDS             complement(29227..30363)
                     /locus_tag="ACZPB4_04185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-bladed beta-propeller"
                     /protein_id="HIR1097453.1"
                     /translation="MRKLYYLVMISVASILTACENRSEEWDVVDFGNDCTVGLQEHLE
                     CRFIPLETKDSVLLKDLYRVCWVDDRIFVFDRSDEINALFVFSDQGNFITRVGLRGQG
                     PKEYLYLTHFFVDEKERILTLVDFGGTALLRYDLDTYQYISTQDVADYFVDCAPLDKE
                     NWIWYYPLGFATPQRENFYLKATDRKGEQDALLGPAYFTSGHTINGSKTLHAFAGNWY
                     AHFPFTPEVWKVKDGMLEPAYKVRFGDKSMPPIEYVKEKGRGGRDFSGDLFRSGYVNS
                     FGLLETERILHATYMCDKVTYFGFYDKDRKEAFSYAFPNFIRATGLTGFYGICGVYKD
                     YFIGKISSTVLLRNQIHYEDLRRIAENRTQDDNPILCLFKIERS"
     gene            complement(30833..32041)
                     /locus_tag="ACZPB4_04190"
     CDS             complement(30833..32041)
                     /locus_tag="ACZPB4_04190"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C45 family peptidase"
                     /protein_id="HIR1097454.1"
                     /translation="MKKLLLLFVLCLCFPVVDKACTSIIITGKATLDGRPLMWKHRDT
                     GAPYNHIGYFDEGGYRFLGLVNSDDPEGAVWTGSNETGFSIMNTASYNLKDDDIKEMD
                     QEGNLMRKALRVCKTVQDFEHFLDTLPRPMRVEANFGVIDAYGGAAYYETNNERYYKK
                     DANDPNLAPEGYLIYTNFSFEGRTDEGKGYVRYENAKKIFKEMRNEGFTPQRIFQQAS
                     RSFYNSLLDIDLMDKGQSPNNRTGWFVEQDFIPRLESTASIVIQGVKSGMNPELTTMW
                     TALGYPPTSVAIPLWVKMGKEQSTLVTYDVSYKTALLDWYSVQLQKNVYSIHRGNGQK
                     YLHWQLLWNDDQSGYIQQLRAVENRIFDLFDAHKTEWEQNGLDTKEIQRLYKEVDKLV
                     NKAFLGLQKS"
     gene            complement(32055..32534)
                     /locus_tag="ACZPB4_04195"
     CDS             complement(32055..32534)
                     /locus_tag="ACZPB4_04195"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HIR1097455.1"
                     /translation="MKTLIHTDKEQIESIIRQSDVCFVGMADTDGTPYVLPMNFGYKD
                     GVIYLHSAQDGRSISILERNPKVCITFSIDHALVFQHPEVACSYRMRSKSVIAWGKVA
                     YEEDFDKKVEALDIIMKQYSDKTFRYSDPAVRNVKIWTVDIDEVSCKEFGAPHKKSY"
     gene            32647..33456
                     /locus_tag="ACZPB4_04200"
     CDS             32647..33456
                     /locus_tag="ACZPB4_04200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head GIN domain-containing protein"
                     /protein_id="HIR1097456.1"
                     /translation="MKTRVSLFIFCIQMVAVCGFAADKRIDGNGNPETREIKISDYDE
                     ITFVGSADFEYEQSDKAPYLSVTIDENLFDYLVTEVEGGTLKIYPKSIKKGFNNNSYD
                     LRPTVYKIKSNSKELKELNTVGSGSFIISKPTKVNRMEINMAGSGNVELRGPVKGYKL
                     ECNMAGSGNIIAKDIQLDNLSCSLASSGEIEVIGTVDRASFNVAGSGEIKAFDCQARK
                     AECNIASSGEISVYATQILDANIVGSGEIHYKGDPEISKSIMGSGSINKVK"
     gene            33477..34301
                     /locus_tag="ACZPB4_04205"
     CDS             33477..34301
                     /locus_tag="ACZPB4_04205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head GIN domain-containing protein"
                     /protein_id="HIR1097457.1"
                     /translation="MKTKLVAVIALIFCAFMAEASKVEGNGNIITKEISVDNYSEIEL
                     GGNIEYSGNNFWGNRSNKKFPVFKYTHGRSASLKITIDENLFPLLSIKSNNGRLAIRI
                     QDGTRIKPTQYVIEGSSKTLKYLKTSGPMDFEAQNAFSEDQLEIKISGSSDVKFPHNV
                     KLRLGEFSVSGSGDLVFEDLDCKNLTSKVSGSGDITLKGKADEARYSVSGSGDIKAYD
                     LSVNDLSCSVSGSGDARVYAKDNMNLSVSGSGDIRYKGPANVNKSKSGSGSIQGAN"
     gene            34453..35241
                     /locus_tag="ACZPB4_04210"
     CDS             34453..35241
                     /locus_tag="ACZPB4_04210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009016752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head GIN domain-containing protein"
                     /protein_id="HIR1097458.1"
                     /translation="MKTKAILLMVFFLGWVTTGWAADHVKGDGKLTSKKISVADYNEI
                     KVDGVIDFNYEQSDDPSTVEVTVDQNLHPYVNIEVKDRVLTIAFKGAKVDHFTKFIVK
                     TNSKWLAAAKVSGNANFMVNSPLTGDETVIKANANSLVQLKETVTVGKLDLNVSGSAN
                     MVVNHLEADKIECDIDGSGSITIKKGNAKEGDYSIVSSGDIHAFGLAVPQLSCKVTGN
                     GLAEVHATDNLKANVIGKGNIRYKGPTAVQQRIIGKGTVEEVKE"
     gene            35238..36014
                     /locus_tag="ACZPB4_04215"
     CDS             35238..36014
                     /locus_tag="ACZPB4_04215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head GIN domain-containing protein"
                     /protein_id="HIR1097459.1"
                     /translation="MKTRIIYLCLLVIFSTTGCISKNARKGINGNKNIVTRTIQVDDF
                     EEIHLGSNIESAKGINPFNKKNRAICNYTQTDGASSLEISMDENLFDLLDIENKDHKL
                     IIKAKSGKKICPTHLVLNTSSKNLKEAGISGSIDFIADQPLQLTNTSFYISGVGDVKL
                     ADLSCDTFKVAISGVGNIYLNGNIKKGKYSVSGVGHVYAFDCPVEDLECEVSGVGGME
                     VNATQKLDASTSGVGSVKYKGNPEHTQKSASGVGKIKQAD"
     gene            36035..36835
                     /locus_tag="ACZPB4_04220"
     CDS             36035..36835
                     /locus_tag="ACZPB4_04220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009016754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head GIN domain-containing protein"
                     /protein_id="HIR1097460.1"
                     /translation="MKKISLLFLICGLFLVSSCIPTQTIKGDGNITTENIPVSEYDCL
                     ELEGGGMVVNYTQSDAPEGLEIKTDRNIFEKYEFNVENHKLKIRPKKEFRKHTNFRPT
                     EFMVTANSRNLKKLAAAGSTHVNINSPLQAEEFEAGLAGSGIIQFHDTASFTNLKIEI
                     AGSGDFVGHKVYCEELNGDMAGSNTIVLGGTVGTAEFSIAGSGTVRAFDCTMDELECK
                     IAGSGDIEASVVNKIKAEIAGSGSVKYKGDPQDIQKKVMGSGKIEKVE"
     gene            complement(36839..37846)
                     /locus_tag="ACZPB4_04225"
     CDS             complement(36839..37846)
                     /locus_tag="ACZPB4_04225"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HIR1097461.1"
                     /translation="MKILITGASGFIGGFLVEEALRRGYETWAGIRAGSSKAHLQDKR
                     IHFIDLKYGDQEALTAQLSDFAREHGAWDYVIHNAGLTKTLDKRNFFRVNAENTHRFI
                     EALAAAGCKPKKFLLMSSLSSYGRGDEKTFRPIRLDDPQRPDTAYGQSKLEAENYIRK
                     QTYFPYVILRPTGVYGPGEKDYFMEIQSVKSGLDFAVGAIPQRITFIYVKDLATVAFL
                     SLEKEEIENRHYFVADGDVYTDESFARMIQDILGKKRVLHARIPLGLVRIACHCSEWI
                     GKLLKKSMTLNSDKYIILKQRNWICDVTPLQDDLGFIPAYPLRKGLEESIEWYKKEGW
                     L"
     gene            complement(37852..38058)
                     /locus_tag="ACZPB4_04230"
     CDS             complement(37852..38058)
                     /locus_tag="ACZPB4_04230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097462.1"
                     /translation="MIPQIICWISLPEIGYIVGIAVILFGCKAVSQNPFISKKQKILW
                     MLTILFLNWIGLLWYYYTFYMKEK"
     gene            complement(38086..38847)
                     /locus_tag="ACZPB4_04235"
     CDS             complement(38086..38847)
                     /locus_tag="ACZPB4_04235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HIR1097463.1"
                     /translation="MDKLIELREVTAGYGNKIALRNVTLDVWKNDFLGIIGPNGGGKT
                     TLLKVILGLLPPITGTIRFYDSDVEVPSLKIGYLPQMSQIDKKFPISVREVISSGLSA
                     EKPLFRSFNRSQRERVDEVIVQMGLEELANRAIGELSGGQLQRVLLGRSIVSRPQVLI
                     LDEPNSYVDKRFESRFYQLLEEINKESAIILVSHDIGTVLAMVKNIACVNETLHYHPG
                     ANVSEEWLGEKYACPIELVGHGDLPHRVLKKHQHE"
     gene            complement(38831..39715)
                     /locus_tag="ACZPB4_04240"
     CDS             complement(38831..39715)
                     /locus_tag="ACZPB4_04240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter solute-binding protein,
                     Zn/Mn family"
                     /protein_id="HIR1097464.1"
                     /translation="MKEFKVLISALFVLILMACGDKRADERIVSVTIEPQRYFAEKIA
                     GDKFKINCVVPAGQSPETYDPTPQQMVQVGKSQGYLRIGSIGFEQAWMDNIRNNNPGL
                     KVFDLSEGIDLLKSPEEEEEHDHHHHHHPGGVDPHTWSSISGAKVIAKNTLDAFVSLD
                     PENKEYYQANYEQLTKEIGETEKTVSGLLHSLDNKTFIIYHPALTYLANEYGLTQLCI
                     EMDGKEPSPAQLKELVETAREHNAKVVFIQREFDQKNAELIAKETGCRLIPINPLDYD
                     WSKEMIHIAKSLADGQAD"
     gene            complement(39873..41162)
                     /locus_tag="ACZPB4_04245"
     CDS             complement(39873..41162)
                     /locus_tag="ACZPB4_04245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009016756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070008 - serine-type exopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S28 family serine protease"
                     /protein_id="HIR1097465.1"
                     /translation="MRRTFNFLLLFFLSVMTVMAAPGDLQEKLASLKGISGIEKLQSD
                     YYPEKYVVRITQQVDPKDPAAGTFTQRVIVGHVGYDRPTIMVTEGYGAAYALNPKYQE
                     ELSKLLNANLVFVEYRYFLESTPEPKNWDYLTAENSAYDLHNVRNTFKQIYPEKWIST
                     GISKGGQTTMLYRAFFPDDVDFSVPYVGPLCKGVEDGRHEPFLRKVGTKAERKKIQDF
                     QLEVLKRKSDMLPLLESYCKNKNLTFRIPMPEVLDYCVLEYSFALWQWGTSISTIPSK
                     SADDQALFDHLMEISGPDYFAENQPNISFFVQAARELGYYGYDVKPFKKYLTIDSAHG
                     YLNRIMLPEELVGKVDFRPALYHKIYNFLKDNDPKMIFIYGEIDPWSAAMVPAFKGKK
                     NEQIYIQPRGSHRARIGNMPEDMKERILTQMNKWLAE"
     gene            complement(41169..42086)
                     /gene="queG"
                     /locus_tag="ACZPB4_04250"
     CDS             complement(41169..42086)
                     /gene="queG"
                     /locus_tag="ACZPB4_04250"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0052693 - epoxyqueuosine reductase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA];
                     GO_process: GO:0008616 - tRNA queuosine(34) biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HIR1097466.1"
                     /translation="MGISQFIKDKAMELGFSACGIAEVAKAGSEEAYFDQWIAEGYHA
                     GMKYMENHREIRLNPDGLVEGAKSVISVALNYYPKVLRNPAEPYISYYAYGEDYHGVV
                     KDKLRQLWKAITEHHPSNNEARVFTDSAPLLERYWAWKAGLGWIGKNTNLIIPGKGSF
                     FFLGEIVTTLVVDTYDSPKKNHCGSCIRCLNACPTGALEGPKRLNARKCISYLTIEHR
                     GEIPVEQAVLLGNRIYGCDTCQAVCPWNRFAMPTAVAAFHPTPSLLSLKKDDLKALSR
                     EDYNRIFAHSAVKRAKYEGLLRTIQYLKD"
     gene            complement(42086..42697)
                     /locus_tag="ACZPB4_04255"
     CDS             complement(42086..42697)
                     /locus_tag="ACZPB4_04255"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HIR1097467.1"
                     /translation="MFIEQPPWFYRALFPGVTWRIPAEKKCVYLTFDDGPIPEVTPWV
                     LDILDTYGIKATFFMVGDNVRKHPEVFQMVIDRGHRVGNHTFNHIQGIKFWTKNYLAN
                     VEKAAEYIPSNLFRPPHGHMRFPQVVWLRRHYHIVMWDVVTRDYSPHMTPNGVFNVVK
                     NYTRNGSVIVFHDSLKAERNMREAMPRAVEWLLKEGYEFKVFE"
     gene            complement(42704..45961)
                     /locus_tag="ACZPB4_04260"
     CDS             complement(42704..45961)
                     /locus_tag="ACZPB4_04260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein O-mannosyl-transferase family"
                     /protein_id="HIR1097468.1"
                     /translation="MGKYKLINNVLGWVVFLIASTVYLMTMEPTASFWDCGEFISSAY
                     KLEVGHPPGAPFFMLTANLFTQFASDPSKVAVMVNTMSALFSGLTILFLFWSITHLAR
                     KIIVEDDKTMSLGQMITIMGCGLVGSLAYTFSDTFWFSAVEGEVYAYSSLFTALVFWL
                     ILKWEEAADRPHADRWIVLIAYLMGLSIGVHLLNLLCIPAIVLVYYYKKFPNPTMKGT
                     LIALLVSFAIVGLMMYGVVQGLVEVCGYFELLFVNTFGMPYNSGVYAFVIILAASLIW
                     AIWETMQDEIHPVRMKISFILSIVLLGIPFIGSGYVIAVILTAALTAYLFMSKKVNIK
                     MLNTILVCLMVIVVGYSSYALTLIRATADTPMNQNAPQDIFTLRTYLAREQYGKTPLI
                     YGQTYVSEVKRENQGGTCVPVSKEGEPTWSRVIKKDKNEKDHYYISRYDTEYEYVDEL
                     SMLFPRMYSSDGRHVAAYKEWAQVKGTPVKFNRCGEMVTVMKPTFAENLRYFFAYQLN
                     FMYWRYFMWNFSGRQNDIQGNGEVSNGNWITGIPFIDEALVGPQEDMPFDIINNKGHN
                     VYYMLPLLLGILGLLFQAYAGKKGIQGFWITFFLFFMTGIAIVLYLNQTPYQPRERDY
                     AYAGSFYAFCIWIGFGVAALAKGLQKYGKLSPVIAGSVATVLCLLVPIQMGAQNWDDH
                     DRSNRYVCRDFGANYLESCEPNAVIFTNGDNDTFPLWYAQEVEGIRTDVRVCNTSYLQ
                     TDWYINQMKKQAYESDPLPISWQPEDYVQGTRDAAYVFPMTDKSIDLKTALDFVRSND
                     PKFKKIPGINQELDYIPAQTLTMGVDSAAVMAAGVIDTANLPYLQKEMKIDLKGKDVL
                     GKQELIILDMLQTNDWNRPIYYAITVSPDQFVKLDPYFQQTGMAYQIVPMETQGTVRS
                     INTEKMYDNVMNKFKWGGVNTPGVYLDENVMRMCKSYRIALFSKLAAALVAEGKNEKA
                     LNVLDKAMEVLPPENVPLDYSALSLGELYYELGQKEKAEMVYKGIADNALRSINWYFR
                     LRPGQLSSVESDLGHNLAVLQEVLRVSKQYNPEFAKPYQEEFDNYRMAYGSVAKD"
     gene            46157..46458
                     /locus_tag="ACZPB4_04265"
                     /pseudo
     CDS             46157..46458
                     /locus_tag="ACZPB4_04265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009016758.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            46477..46701
                     /locus_tag="ACZPB4_04270"
     CDS             46477..46701
                     /locus_tag="ACZPB4_04270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(4Fe-4S)-binding protein"
                     /protein_id="HIR1097469.1"
                     /translation="MGKKIEYTNGELTIIWQPELCQHAGICVKTLPGVYKPKERPWIQ
                     IENATTAELIAQINQCPSGALTYRMNKEVK"
     gene            46833..49655
                     /locus_tag="ACZPB4_04275"
     CDS             46833..49655
                     /locus_tag="ACZPB4_04275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HIR1097470.1"
                     /translation="MIKRHSILTAILLCFVAFTQVMAQEMQEPEPLPIDPKVRYGKLS
                     NGLTYYIRHNDQPKDRADFYIAQNVGSILEEDNQRGLAHFLEHMAFDGSRNFPNNGMD
                     EYIESVGMRSGENFNAYTSFDETVYMITNAPVNKSGVVDSCLLILHDWSGFLALTDSA
                     IQKERGVIREEWRTRQDAQTRLWEQQLPKMYPGSRYANRMPIGSIDVIENFKPDELRA
                     YYKKWYRPDLQAIIVVGDVNVDQVEATIKKMFADVPAPVNPAKREQVSVPDNDLPLIS
                     IAKDKEASNTILYIFYKHDKLPNDLNRTIAGLVKDYIQQICASIMDERFDDILHQANP
                     PFIYAQAYDDDNFMIAKSKGAWTVAALAKEGEIDSTLTTLVKETQRVKQYGFTPSEYE
                     RARINVLKQYESAYNERNNQKNDAYVREYVNHFTNGGYIPGIEMEYTLLNQIAQNIPV
                     EQVNQYIQDMIGEDNIVIGLTGPDKEGIKYPTEENLLRTFLKARQMPVEPYKETVSNE
                     PLVPTLPTPGQITETKTGQPFGATVFTLSNGIKVVLKPTEFKKDEIIMTATSPGGSTL
                     FGTKDIDNLKVFNDVIEIGGLGNFSATDLSKRLAGKKVSCALSLSQDSENVNGMAAPS
                     DLRTLFELIYLSFTAPRMDEEAYASFETRTKAQLQNMELNPMVAFSDSLSKAVYGDNP
                     RASRLRPQDFEHISYPRIMEMRKERFSDASGFVFTFVGNIQIDSIRPYIEQYLATLPS
                     QGKIEKGNPAEVPSMRKGDYMNRFNRSMEIPKVTVANLYTGQMEYNLENIITATALKQ
                     VMDLVYYEKVREKEGGTYGVGVSARISPFPEGRTTLQIFFDTDPAKWEQMNTIVRNEL
                     KRLSEVGPRQEDFKKTQDNLLKRHAEVLQENSYWLNVLDDYYYKGFDTDTDYESIVKA
                     LTPEKIKAFAQKLLGQGNRVEVIMQP"
     gene            complement(49695..50597)
                     /locus_tag="ACZPB4_04280"
     CDS             complement(49695..50597)
                     /locus_tag="ACZPB4_04280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HIR1097471.1"
                     /translation="MKSTLSISSLSRQVLLRETRDYLMIALGMILYGIGWTVFLLPND
                     ITTGGVPGIASIVFWATGFPVQYTYFLINAVLLMLALKILGFKFSIKTIFAVFTLTFF
                     LSLIQELTAGMHLLQDQPFMACVLGASFCGSGIGIAFSSNGSTGGTDIIAAIINKYRD
                     ITLGRVMMICDMIIITSSYFVLKDWEKVVYGFVTLYVCSFVLDQIVNSARQSVQFFII
                     SKKYQEIGKEINALHRGVTVIDATGLYTGQEQKMMFVLAKKRQSTTIFRIINDIDPTA
                     FVSQSAVIGVYGEGFDHFKLKKSK"
     gene            complement(51295..51750)
                     /locus_tag="ACZPB4_04285"
     CDS             complement(51295..51750)
                     /locus_tag="ACZPB4_04285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097472.1"
                     /translation="MEAENIYPVTEPVGSEQDAPVSNMEMLSDVFFKEEARRLKEAFC
                     FERDADDFDYLNHQLQSVKNLLVGLKLPWIQIAPILYRCMAVYLQRPDQHVSNMKVRY
                     LSTQLMDGVLLLSQNGRLINDLLTFFDRQIKDIQRLREEKCEEMENVRL"
BASE COUNT        14729 a        13119 c        10824 g        13385 t
ORIGIN      
        1 gtaagtgatc ggggagattc gatacataga ccgttttgga gcgccttttt atataatctt
       61 ctcaattcgt attccatgtt cctgttctct atccacagac gttctatatc aaggtcttgg
      121 ttcgtgattg ttttcttgta ttcggtcagg aagcccatgt tttcttgcaa gcggagcgat
      181 atgaccttat atcggcgaca gattccgtcg taggatatac cacaacgttt ggctacgtct
      241 tctatcttgg ctccggaagt tatttccgta aagataagtc ggtctttctt gtcgtgtatg
      301 aatgttgata gttcggcgat aatgagttta agtaggggag agatgttttt aagggatcgc
      361 aggcagaaaa ggtaatcatc gaattgggag atgatctcgt ttatctcttc ttccttgtct
      421 tggatgataa gttgcaggta tagcttttgt attcccatac gctcgatatg ggaaatgaat
      481 tcacgcaaat tggtcagatc gactaggcga acaccttgct tcacgacgta agatgctatt
      541 tttttagata tcgcccattg ctggatttct tcagatggaa agccggtgat acgagcggct
      601 tcttcaatag taataaactc aggcataact atttgattaa agtaaaactt atactattta
      661 tctttaaaaa gggcgttatt tggcgttata ttgaagagct ggcctttcat tataaaataa
      721 agaaagggcg attggctgaa cattacgttg acaaaggttc cgctaaaaac ccacattaga
      781 gtaaagtcag ccgcacgccc cctttatcta tatacaataa tcttatccat actttaacag
      841 catagataac acgtatattc ggtaaagggt tgcggggcct tctttgcgct tctctaaagt
      901 tgaaaaattt agcggattct gtcaactcgc acaaatatcg cacgcaacac aaggcttcta
      961 acttaaaagc cttttattgt cgcaaatata cgtatttaaa aatattttag tctataataa
     1021 tccatacgtt ttctatttta tcattgtttt actaccaaca aagaaagaat aagtagataa
     1081 aaacctacgc ttttaccttt tgcttttctg tcttaattac tagctaggca aatatatgat
     1141 atattcttta attataattg attattaaga aaaaaatcaa gatggcaatc cattaaacag
     1201 tacgaagact actaccctaa agtctacgga atgaccttac aaaactcttt taactcttcc
     1261 tttatactac taagctctct ttccatagat tgtttgctgc ttttcacctc atcttttaca
     1321 atgttcaaga cacgcttaaa accataataa ggcataagaa acgggaacaa cagaccgctg
     1381 atcaagacaa acaaaatcac agtgatttta agcgcaacaa aatcctcata ggtaaaacaa
     1441 acagaagata catcatctga tagcgcacac ccaccggtcg ttaccacagc aaaaagaaat
     1501 gatataagaa acaatccccc aaagtgtttg aaaacatatt cataagtata gaagccaaac
     1561 tcataatggc tcttagcttt taaccatgcc attacacata taggtattcc tatagtgaat
     1621 gatattaaac atttagccca gataataggg ataaaagttg acaagaacaa acaagtcgca
     1681 taaaacatag gaaatgcgaa acacatccat ttccacctta tccacctaga aacaaacact
     1741 ttcgtttttt gagaagaacc ttcttcagtc tctatccgta tatctctaaa gaaaatcttc
     1801 cacatcatca accagaaaat acccgagaaa gccacaaaga tagtcaaaaa ggaaacaaca
     1861 aaatcgctcg ttcccgcaac tcccacaaca atctcatcac aaataaaaac tgttaagcag
     1921 aacaaaagcg catataacgg agctataacc tgttcttttg acctttgaat tttctctatc
     1981 aagtcatgag ctggcttcaa gaatttagag gaatatccgg atttaagttg atcgaacgta
     2041 gcttgaagtt tcatatccat agccatagca ctaattagca actgcttgca ttctggtctt
     2101 gttttcgcct ctacacgcaa ttcatttata tagcgctgca atagtttata atcagagttt
     2161 gccggcacat cgttgatcac atcgaacccc actgctttat ccaaagattt gatctcttca
     2221 tcaatacgtt ttcctatctc atcaagaata ctatgtataa aattactttt gtccaaaatg
     2281 acacataata caatcaatga tgccaatata ccaataaatg tctggcttcc tccaagaaac
     2341 agcataccaa ccttctacta attcaacttg atctcctcac ctaccaacga catcgactta
     2401 aaagtagctt ttaccttgct caaaatctct tcaggtggat ttatcgcaca tgtagcttcg
     2461 tgcgtctgcg gatttctttc cattctaaca atgttggtat ccgtatatga gacatgcgcc
     2521 atatcgcttt tcaagaataa attatcttcc aatttaaaaa gacgtatctt ctcggaactt
     2581 actccatcac taaaaacacg aagatcgatt aaatctctca agaacttacg atcaaacctt
     2641 tcaaaataaa tattcaagga tacattggga cggtttatga actctctcaa agacttaata
     2701 acctttttct tgatctcatc tcctaatgca gtctctcctt ccttgagatc ataattacta
     2761 tcttgattga tatgattgta gaatccctca cggaaaacag acatttcgcc acaatacata
     2821 ttaatcacat ttgatttatt aagcataaag cattcaataa cagcattatg agcacggtca
     2881 tggttcataa caaaatccat ctctccacgg tcaaaagtat cgcagagatt atcataatat
     2941 tcatttagat cttctaatct catcaaaaag cacagtattt aactatatgg gaaacatagt
     3001 tttatcctta aacatctggc aaagatacta aaaaacacaa acaaaatact tttatagcgc
     3061 aaaaaagatt aggtacattg ccaaatggct tttttaggta gaaagttacc agttaactaa
     3121 catttcaaat gtaagttagc ttcaacggca aagtaagtta acttcattgg caaagtaagc
     3181 taacttaaat gaccaagtaa gttaacttca taaatccggg ttgaaatccg caaacgacat
     3241 acaacacgcg tctacactcc caacactata taaccgctat ggatatttga agtattgata
     3301 ataggcggtt tacttctgtt atccgtaact ccaaccttat cagtcaacaa gcctttcatt
     3361 aaaagataag cacatcatga tggcacgact gtgccatccc aatggcacac cattgccata
     3421 aggaaggcac agctatgcca cgctgatggc acagccgtgc cacgatatgg aaaatgattg
     3481 gcactgtgga agtctgttaa ctaaacagtt aaggatggat aaataattat tcccctaact
     3541 tatcaagcaa ctcatacgac ggaacgaaga aaagagttcc cgttatcggc gtgctgaagt
     3601 ccagcagacg atccgtattg cctacaggat caccgacgaa catattctcc agcattcgtc
     3661 gggtggtgct gaacgtgctg gcataggcga taaaataggt accgtattca cctttggagg
     3721 tatgggcgaa tggcatgtta gcacggacta ttttcagatc gtctccgatg ttcgtcacgg
     3781 cgttatgggc gttcttcggt ttttcctcat ctgatagctc gacatcgttg aatttacggc
     3841 gaccgatgac tttctcttgc tcttccactg gaagcgcatt ccatgccacc atatcatgaa
     3901 tgtatttttg cacaaataca taacttccgc ccataaactc ggggtcctca tcgcctatta
     3961 ccgcgaaacg ataggggtct tcatccacgg caggattctc cgtaccgtcc acgaaaccga
     4021 taatcgcctt accgtctcta taccgaaaac cgtgggtctc atcgatcgat tccacgacac
     4081 ctcgcagttt ctggtctata atggaggcga actcaaagca cagtcccatc tgcttacagc
     4141 ggatgtggaa tagtaaatcc ccgggggtag aaacagccgt aagcttaact cctttgatct
     4201 cttcaaacgg ttgcaattct ttggggtttc cttgctccgg aaagaaacgt ttccaagcat
     4261 ccgccccgaa tcctatcgta caactgaatt gcatatcagg atagcgattg cgcatactac
     4321 gtatcaaagc ggagaaatta gcgcacacgt cctttacctt atcaatcgtg tcggggagat
     4381 cttttagagc atagacaatg aaaaccgcat tctcgcccgg tttttgggta acatcttgcg
     4441 gatagttagc gttcaatgga ttttgtagag agttcatagc acatctttaa ttatattgtt
     4501 attatatgga tataactcta tagatgcgct cttgttcaag gaaatgtaac gaaaaatgtc
     4561 ctagcggtta tttttcaata tctatttgta gagacggggc acgccccgtc tctacaactg
     4621 ggtagttatt tcacctccac gctgattctc tgcgtgatat ctgaggcgga ggctcctagt
     4681 tggaggatga actcgccggg ttctacgacg aattggcttt gtgcctcact atagaaagct
     4741 aaagaggata cggggatgtc caacgtgatt cgccgactct caccgggttt aaggaatacc
     4801 ttcttgaagc cttttaactc cttgaccgga cgcatcacgg agcaaaccgg atcgcttaca
     4861 tacaattggg ccacctcagc tccttcacgg tctccggtat tggttagggt gaaagtcgct
     4921 tggatcgtgt ccgcttgatc atacgtcttt ttatccgtat tcagattaga atagttgaat
     4981 gtcgtatagg ataagccgta accaaacgga taaacgaccg gaagcccctt cgtatcgaac
     5041 cagcggtaac ctaccaagat atcttcctca taattcactt tcagatccct gccggggaag
     5101 ttgcccaacg catgcgccgg ggattgatcc aagctcacgg gagtggtgaa cggcatcttc
     5161 ccgctcggat tcaccttgcc ggataatacg tctaccaagg catttcctcc ttccatgccg
     5221 ttgaaccaag cccaaacgat agcaggggaa caaatatcca cggcagccat gttcagcggc
     5281 gatccggcga tcatgatcac gatcgtacga ggattcgcct ttaccacctc ttgaatcaac
     5341 tcaacctgcc cgtatgggat atccatattc agacggtcga acgactcggt atcataatca
     5401 tggttcaaac cacaaaccaa aagggccacg tcactcgtgc gggcaacctc taccgcctct
     5461 ttcaataatg cgtcgctttc ctgtgtcttg gaagagaaag taccagagct ttgcccatta
     5521 ttgcttccct ccacgaaagt agatagcttc tcataacctt gggcaaaacg gatatccacc
     5581 ttatcgcccc atttcgcacg aagcgcctct aatggagtta cctcgtaaac cgccttgatc
     5641 tcggaactca agccaccatt ggaatgtttg cgggtagcgt tatcgccaat taccgccaga
     5701 ctcttgatcg aggagaaatc caacgggaga agattattct ggtttttcaa taggacaatg
     5761 gcttcggcag ccgcgtcgta agtggcttgc tgatgctctt tcgtattcat ggagccggga
     5821 ccgaaacgct ttttcgggtc caagacattc gtcttgatca tcacacgtaa gacatcgccc
     5881 accttctcgt ccaccaagct cataggaacc ttaccggact taacagcctc gatcaagggg
     5941 ttggcataat accaatcctc atatttatca atcagcgtgc ccatctccag atccaagccg
     6001 gcctccatag aaggaaccgt gctatgagca gctccccaat cagttacata tacgccatcg
     6061 aatccccatt cattccgaag gatcttgcga accaagtagt tattctccgc gcagaactcc
     6121 ccacggaatt tattataagc ggccattacc gtcaaggcgc ctccctcctg tacggccgcc
     6181 ttgaaagcgg gtaaataaat ctcacgcaag gcacgctcgc tacattccac atcgatagtc
     6241 gtacggtttg tctcttggtt attcacggcg aaatgcttta cgctgcaagc cacgtcacgg
     6301 ctctgcaaac ccttgatata agcgaccgcc aatacggagt tcatataagg gtcctcgctc
     6361 atatactcga agttacggcc acaaagcggg gagcgaatga tattcacgcc cgggcccagc
     6421 aacacatcct tcttacgcca gcgagcctcc tcgcccagca cctcgccccg acggtaagcc
     6481 aactccggat tccaagcggc ggcgaaagcc gtgccggtcg ggaaataaga ggcggaatca
     6541 tttgtccaac ccgcatatgc ccagtcgtgg cgattgatct ccgcacgtac cccgtgaggc
     6601 ccgtcgctca agctccactc gggaatcccc agacgctcta ctccggcaac atagaatttt
     6661 gagttaccat gcaataatcc gaccttttcc tccaaggtca tcttcttaat cagtttctcg
     6721 atacgtttct ccatttgtac cttctcttta tccgtgacct gcgagctcgc ggcagccgcg
     6781 ttcaagaata gcccgcaagc gatcacgcct attatctttt tcatttcctc tttatttata
     6841 ggtttattat tgcgcttgaa tcgttaccgt cgcctcgggt aagccctcgg ctatggcttt
     6901 taagtggatg tcgccttgtc cgcccttgtt ccggatcacg accaaggctt ttccgtagta
     6961 agcttgccgt ttcggtttac ggaggctgtt cggatcgttc ggatctccgt tatccgttcc
     7021 ggcgatctca cccgggccct ccacggagaa acggatcaac ggggtagcgt cgggaacccg
     7081 gttaccatcg atatcgcata catctacggt tacaaacgat aggtccgagc catccgcttg
     7141 gatgacacta cgatccgggg tcaagaccaa acgggccggc tctcctgccg tatggatctc
     7201 tttcaccaag acctccttac cccctaagcg ggagacggct ctcaaggttc cgggcgtaaa
     7261 aggcatacgc caagagacat gataggtact gtccgttttt tgtcgtacgc ctaggctctt
     7321 tccgtttagg tatagttcca cctcatcggc attgttataa taggcccaga tatccaccgg
     7381 ttcgccttct ttccagttcc aatgcgggaa aatgtgcaat acgggttcat ccgtccactc
     7441 gcttttatac atataatata catccttcgg gaaacccgcc agatccacga taccgaagaa
     7501 gctgctccgg ctgggccacc aatagggggt aggctctccc aagtaatcga aacccgtcca
     7561 gacgaacagg ccggatacat gcggaagcgt cttcaccaga tgccaagtct tctcgtgcgt
     7621 agagccccaa ggtacatggc aattatcata agaggagcaa acatgctcgg gagcctcgaa
     7681 aggcttgtcc cacgattccg gacggatata aatatgatcg gacggcatct cataatagcc
     7741 acgggtcatc aaggccgagg tagattcgct cacgatcagt ttctttccgg ggaaattccg
     7801 gagaaacggc tcgaaatatc gctcatggta gttgaagccc agcacatcca aggcatccga
     7861 gcggaacaga tgattcgcag ggtttacctc gttacaaccg gcggtaacga cccgggaggt
     7921 atccagccgt ttcacgatag ccgccagatg acgggtgatc aaggattgac ggctaagggt
     7981 cgtatccttc agcaaagcgg gatcgatggc atggccggca ttcaagatca ggttcgccgc
     8041 ttgcagatcc agctcggtag cgtcggcatg actccattgc tcaagtacct cattgcctat
     8101 actccacatg aaaacagagg cgtgattccg gtcacgcaag atctcgtccg tcaaatcccg
     8161 ctcgtgccac tccgcgaaat accgggcgta atcgtatggg gacttacggc gttcccacat
     8221 atcgaaagac tcatcctgta ccagaaggcc catacgatcg caaagatcca gcaactcggg
     8281 tgccggggcg ttatggctgg tacggatcgc gttcacaccc atctccttca tgatctgtag
     8341 ctggcgctcg atagcccgtg tattcacggc ggcacccaga cagcctaaat catgatgcag
     8401 gcaaacccct tttatcttca aaggcttatc attcaaataa aagccggtag cggaatccca
     8461 acggaacgag cgaaggccga ataccgtctc gtaacgatct accaccttac cagccacttt
     8521 cacttccgtg acggccgtgt agagcgaggg agaatcggga ctccaaagct tgggatttgg
     8581 gatcgagaac tgatgatcga cagatgcctc ccgcatacgg gcgtcgtaac agggcgtata
     8641 cggtacccgt aatagagttg ttacgggtgc cgtaacaact ctgttacggt catcgtaaat
     8701 agaggtagag atttcggcat ccctatccgc ctccgagcta ttccttattc tcacctccaa
     8761 cgagaaggta gcctcctccg gcgagatcct catgtcatgc acgaaagtac cccagttgtc
     8821 cacatgtacc ggattcacct ttactaacca tacgttacgg tagataccgg agcctgaata
     8881 ccagcgggaa ttcggttgct cgctattatc cgccttcacg acaatcacgt tcggttggct
     8941 tccatacctc aaataaggcg tcaagtcata acgaaacgat acataaccat tcggacggaa
     9001 tcccagcgaa tgaccattga tccagacctc gctattccgg taaaccccgt cgaaatcaac
     9061 ataaacaacc ttaccccgat ccgtctccgg aagggtaaat gtctttcgat accaaccaat
     9121 cccgcccggt agcgcgccgc cgcccggggt agacgggtta tcgagggaga aatccccctc
     9181 gatactccaa tcatgcggta aagataagat acgccaagtg gaatcatcgc tgtccgggga
     9241 tgaataatcc tgaacgctat ccgacaaggc aaatttccaa tcgtcattcc atgnnnnnnn
     9301 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9361 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnatgcggt aaagataaga tacgccaagt
     9421 ggaatcatcg ctgtccgggg atgaataatc ctgaacgcta tccgacaagg caaatttcca
     9481 atcgtcattc catgggctac gttcacgcac ctgctccccg gtgggggaac aggcggtgag
     9541 caataggccc agaagccacg caagtggccg attcatcagt ggtatcatta gtgattatat
     9601 agtttaattg atactaccca gttgtagaga cggggcgtgc cccgtcttag cacagactga
     9661 tgggtattat ttaaagttac catttagagg ggttgagacg gggcacgccc cgtctctaca
     9721 actagaggtt taccttggta agatattgtc acgtccttgc cagcggggtt ctccggcgtg
     9781 atgagacgta ccgtgatctg acgctcgcgg atcatgcccg gatagtcgcc ctcccgtgcg
     9841 ccgatcgtga gcgttcgcct cgcatcatca taaacaaacg ggatggtagc gtaatttcct
     9901 ttctcgtaat cgtaggtcac gccattatcc tcatataagg tgaaggagcc gtcggcaccg
     9961 gcgtaaacag agacgattaa gtctttctgc tcctctttcg tagactggat tacctttccg
    10021 ttcggtacga tagagccggc tctcacgaac aaaggcatac gctcataagg agcatccaca
    10081 tgcattgtcg tcccgccttg tatacgcttg ccgttgtagt aatcgtacca aatgcctgac
    10141 gggaaataca cctcacggtc gcgagcctta tactcataca ccgggcatgc catgaaggcc
    10201 gggccaaaca taaactggtc gtctatatcg taagtcttct catcgtccga ataatccatc
    10261 accaaggcac gcatgatcgt ataatcctca aaatgcgtct tggaggccaa gctatagata
    10321 tacggcatca attgatagcg caactcggta taatacttca tcgattggta cgtaggcgat
    10381 ccttccggag cgatattata gatctcgcgg caaggatatt gcccgtggct acggaacaac
    10441 ggacagaaag ctccgaactg ataccaacgg ttgttcaact ccctccattc cctcaaatcc
    10501 tcgctacctt ccttagcggc catataacgg ttctccacgc tgaagccacc gatatccatc
    10561 gtccagtaag ggataccgga catggcgaag ttcaagccgg cgctgatctg cgctttcata
    10621 tcctcccagc gagtaccgat atcgccactc catgtagcgg tagaataacg ttgctggccg
    10681 gcgaaaccgg aacgggtcaa taggaataca cggtcatccg ggtttacgct acgttgtccg
    10741 tcgtagatcg cctcggcgtt agccaaagcg taagcgttga agtatttcgt ggacgggccc
    10801 agataagtcg gtccgcaaag cgccttgcga tactcgatat ccgtattatc ctgtacgttc
    10861 ggctcggaag cgtccatcca ccaagcgtcg atgcccaagg aatacagatg ctcgttcatc
    10921 tgttcccaga aaagcttgcg ggcttccggg ttgtacgcgt catagaaaga accgatataa
    10981 cccggataaa tccagtcacg gatactatcc ttaatcgcct gctgatacat agcacccagc
    11041 gcgtccaact ctttataatg ctctgtcgta taatagaact tcggccatac ggagatcatg
    11101 atacgggcat ccttatcgtg gatctcctga atcatacctt tcgggtccgg gaagcgttcc
    11161 ttatcaaact cgtggctacc ccatgcgtct accggccagt agctccagtc ctgtacgatc
    11221 acatccaagg gaacctgccg ccggcggtat tcgttcaagg cggtcaatag ctcctcttgc
    11281 gtcttataac gctcacggct caaccagaat cccatcgccc atttcggcat gatctggctc
    11341 ttgcccgtaa ccgtgcggta accgctgatc accttatcca tggaagactc tccgttgatg
    11401 aagtagtaat cgatatcatc ccccatttcc gaccagaaag ccaaccgctc ccgctcctcc
    11461 tccggtagcg gagataatac cttcaagccg atataagaga catcgccatc cggcaaccat
    11521 tcaatacgga tcggataacg tttgcccttt tccagatcgg ccgtagcctt gtaatcattc
    11581 gggttccatg cagcacgcca acgttccggg atgatctcct cgttattcac aaataccttg
    11641 gtataaccgg cgtaatgtag tttgaaatga taagtacccg tctctttcgc ctcgatctcg
    11701 ccctcccaag tagcggaagc gctcggcttc gggaagtctg ccggcaggtt cttgatggtt
    11761 ttcagattct cataatctac cttatcttca tcccgctgga ttaaaacgga attcttcgcc
    11821 ttatccgtat agtaggtagc ggtcaacgcc cctgccctcc cgtcttttcc gtataggcca
    11881 aagacatcgc ccaaatcggc gtatggacgc ttgtcgccga aacggctcaa ggaatagtta
    11941 tgccaaagta caccataccc ttttgaggaa acgataaacg gcacgctcac cttcgtgtta
    12001 tattggaaaa gctcctcgtt cttgcctttg tagttgaact catcgctctg atgctgtcct
    12061 aggccgtaaa gcccttcctc gtcctcgctc tcaaatactt gacgtaaggt atagcctttg
    12121 gttccttcca cctcgatcgg cgtaaattcc ttgcctccgt ttgtcttctc acgaaggatc
    12181 gtgtgtccgt tggcgtcggt aaagcgaacc tctccggtct cccgtgaaag acgggcctgt
    12241 gtggtttgcg tacttacgat gatcgtatcc cccgaggtcg ttatctgaaa cgatggggcg
    12301 ggcaacgatt tcgtgtcctt gatcaagttc acttggttgg aaaacttacc atccggagag
    12361 gcgattaccc ggataatatc atcagagatt acttccaatt taacagcctt cgcctgtccg
    12421 gaacggatat cggcgaccaa gccattctcg accttccggt aagcggaatc agtcatgcag
    12481 gaagtcagca gggaaagccc taacgtgaat accgcgatgt gttgtttcat attctataga
    12541 ttctttaatt atttccgatc agcaatgagt ccgaacaggt ttttccatac aagaaaaatg
    12601 gttcttcatt cgttggcaaa attaaagggt ttgcggcgga caggaagcca taaatgtttt
    12661 gggttacggg gagaaccgta aaaaggtagg ggaagaatgt ttattttaag gggatatttt
    12721 gttatatccc ctaattacgt ggcatttatt tagaagaagt ttatttatga tagtcagagg
    12781 gaagccttcc gaactcatcc ttaaaatact tccggaataa cttcacatca ttgaaaccgc
    12841 actccagcgc gacctcattg acccgcatct ggctcttctc caataactgc gccgcacgct
    12901 tcaagcgcac cgtacggatc aactccaccg gagtcttacc cgtgatggaa aggcatttct
    12961 tgtagaagtt cacacgactc atgcccatct cccggctcaa ccgttctaca gacaactccg
    13021 gattggcgat ctgctcctcg atataggcga tggccttacg catcaactcc tcatccatgg
    13081 agctagcttg tacctccgtc aaggcgatgc ccatggtaga ggactgcata aaggcctttt
    13141 gcatcttctt cttcatctcg atcaaatgcc gcaccttcaa gagaagcatc tccatattga
    13201 atggcttgct gatataatca tccgcaccgg cttccagacc gaccagttgg ctatctttag
    13261 cggactttgc cgtcagtagg atcaccggga tgtgggaagt ccggatgtct cccttgatcc
    13321 ggcggcataa ggtgataccg tcggtgatag gcatcatcac gtcgctgatc accatatccg
    13381 gcagctcctc cggaatgagt ttccacgcat cttctccatc cgccgccgtg agtaccgaat
    13441 aaacgccact caagcttaac ttcataaatt cccggaaatc cgtgttatcg tctacgacca
    13501 gcaacgtagg tcttcccgcc ggagacgcat ccttatcggc gatctccgca tgctcctcaa
    13561 ccggaggcaa gatatcccct tcggcaattc cttccggagc cgagataata tcttggttat
    13621 ccaaggggat caccggcagc gtaaccgtaa acgtactacc cgctcccggc tcgcttttca
    13681 cggttatcgt cccatgatgc atccgcacga attcccggca taggtgcagg ccgatacccg
    13741 tacctaccac gggatttccc ttatccgggg aagccacctg ataaaagcga tcgaagatag
    13801 ctccttgttt atccgcagga ataccgatac cgctatccga cacctcgata accagtttgt
    13861 tctctccctc cttctccaac cgcaagctaa gcgtcaccga gatagtacct ccctccggcg
    13921 taaacttaaa agcgttactc agtagattag agacgatctt gaagacctta tccgtgtcaa
    13981 acttcatcgg gagagacgtg aagaccgagg agaaagagaa atgaatccgc ttttgctccg
    14041 aaagctcctt gaaggaataa gccacgtcac gcacgaacgg gacaatatcg ccggtagaca
    14101 agaccaagct atccccttgc atatcgatct tgcggaaatc caataactgg ttcaccaatt
    14161 taagcaaccg gtcggcgttc cggtagatca acttcaatat ttgctgggat tccaggtctt
    14221 tctccgtttt catcaacttc tccaaaggag tcatgatcaa tgttagcggc gtacggaact
    14281 catggcttac gttcgtaaag aaacgaagct tcatctcgtc cacctcatgc tgctgacgca
    14341 cagtagcccg ttcttgctcc tcctccaact tcttttgctg gatacggaaa ataaaacgta
    14401 tcacgccata cgccaataat ataccagcta tgatatacaa agctattgcc catccggtag
    14461 cccagaacgg aggcaggatc gtgatctgca agctcgtgat ctccttgctc caaatccggt
    14521 cgttattcat cgcctttacc ttgaaagtgt aagttcccgg gttcaagttc gtataggtaa
    14581 tacgacgttc caaggcgctt acggtagtcc attccgagtc gaagccctcc atcttaacag
    14641 catatttatt cttcaaagga aggaaatagc aacaagaaga gatggtaaag gagaaattac
    14701 gttccgtata attcagtttc aattgcttgg tacaggtgat atctttatcc aaaatcacat
    14761 gcccgtcata cgcctctctc gccgttatcg ggacattatt caccataagt ccggttatca
    14821 ccgccggtgg agcatagcta ttataacgta tccgggcggg atcaacgaag gtaagaccgt
    14881 ttgtcccgcc aaacgccaac tcacccgttt ccagtccgca agcgctattc acgttaaaca
    14941 cacgtccttg aacgccctca ttctcatcat agctattcca atcgaacgta taattattat
    15001 ccgtatcccg attcggaacg atattcaata agccgttctt cgttcccacc caaaccgtat
    15061 gatatttatc ctccaagata gacatgatgc tgttatccgg taatccggaa gaatggttca
    15121 accgatacat cttatcattc aacctatcat atatatgtag cccataatta ctcccgatcc
    15181 atacccattg gcggctatca caaaatacga cattgatgat ttgatcctca aacacggaac
    15241 gtccatcctt cgtgccgtta aaagaagtaa cagcccccgt ctccgggttg atccagttca
    15301 ctcccaaaga agttccaacg acaatattcc ccttctcatc cccggaaagg ctatatacga
    15361 tatccgagtt aatcgcattc tccttatccc ccatgcgata atacgtccat ttcccggtag
    15421 attgatccaa gcaatccagc ccgccttcca acgtaccgat ccacaaacga ttcttggcat
    15481 cgacatacaa actatacacg ctattattgg ataagccgtc cttactgccc gggatatccc
    15541 gataatgctt gaaacgtttc ccgtcaaaac cggtcaaccc ctccatataa gtacccagcc
    15601 ataacttgcc atccaaatct ttcgccatac taatcacgac atcgccggag atagcgttct
    15661 cgctttcccg ccccgcccgg tagcggacat actccccggt ttcccgatcg taacgtaata
    15721 ggccgtttcc gctagtaccg atccacagat ccccttcttt atcttctacg atacaattaa
    15781 agtcattgtt aaagatatcc cgcatcaact ccaaaggata ccggatagtc tggaatttaa
    15841 aaatgctctc atgataatag ttgatgccgt ttttataagt gccggcccac ataatccccg
    15901 tatcatcccg atacaagcag atcacgctat tctggctcaa actcgtttgg ttaaacgggt
    15961 tatttcgtat ataacgcatc cggttcagac gtttatccaa gatattgata ccgccatgat
    16021 cggtagcgat ccagatatta ccgttcatat cctccgccac gtcacgcacc attatagagg
    16081 ataaagcgac cgaggtttcg gtcgtataat gtttccactc cttgcttttg ggatttaggc
    16141 gaaagagacc tctactatat ccgggattta agaaaaacca cagatccccg tcactatcgg
    16201 cgaacacata gaataactgg gcattcgcat attgagtcag atactcatcc cgatagacag
    16261 attctccgga tgccttatcg atcccctcta ccactcccga ggtatggact acatatagac
    16321 gatcgcccac gtcactcata tcacaaaccc ggccatcctc tttatttagt ggatacgaat
    16381 aaatctttcc cctcgcttga tcataacgac aaaattcatt cgtataggta gcgaaataga
    16441 gttgtttatc attgtcgacg aatatcttag cgggaggatt ctctagacgt aagctatcta
    16501 atatttcctt ctccggaata aaacggtcat taccgggctc atatacgcaa agttggttcg
    16561 tattataggt aatccaaata cgcccatcag cggtttcttg aagttcggag acatgctcct
    16621 ccctaaaagg caacccgctt tccttgtatt tataatgctt aaactcatac ccatcaaaac
    16681 ggtttacccc agaagtggta cccaaccaca taaacccctt ccggtctttc aggatacaag
    16741 tgatctcatt ggaagacaga ccgtcctgta ctcccagacg gttgaaaaga atatcttccg
    16801 ccgcaagtcc ggatcccaat attccccaag acaggatcat tatgatacag agtagagttt
    16861 tcgttttcat acttagcaaa tatagatatt tcccgagaac gaaccaaacc aaccggtatc
    16921 taattctgct gcaatggggg ttgcagtaaa catacacgta aagtatccat atataagaac
    16981 atgattatta aaaattatcc cgtacatttg tctttcgatt ggaatagaaa tgaataaggc
    17041 gcaatgattg ttgtaagaga ttttgacaga ctgaaaggaa aggaactggt ggctacgatc
    17101 ggatttttcg atggtgtgca tctaggacac cgtttcttaa tcgacgagat gaaagagatt
    17161 gccaaagcac gtaacctgcc atcggccgta atcaccttcc cggaacatcc ccgggctgta
    17221 ttgcatgcgg attaccaacc gaagctatta aattctttcg aggaaaagtt acagcaatta
    17281 gagactaccg gagtagatta ttgcatcgta ttggatttta cgatcgagct atcccggttc
    17341 tcggccaagg aattcattac ctctatttta gcgaagagcc tgcatgtaaa gaccttattg
    17401 atcggatatg accatcgttt cgggcacgat cggacggatg gcttcgagca atatgtcgtt
    17461 tatggcaccg aatgtggtat cgaggtgcta aaggcatctc cctatgacga agggaatacg
    17521 gccgtcagct cttccgagat ccggaaatta cttcaagccg gaaatgtagc ggaagccgct
    17581 tatttactga cctatcccta tcaattgctg ggccatatcg tcagcggcta taaagtggga
    17641 cgcacgctag gatttcccac ggcgaatata cgggtagatg agccttttaa agtcattccg
    17701 ggtattggcg tatatgccgt atgggtggag gtggaaggcg aacgatataa gggaatgctt
    17761 tatatcggtg accgtccgac actcaataat gggaaggaca tatccatgga ggtcaacatt
    17821 ctggatttct ccggagatat ctacaacgat agcattcgtg tctcattcgt tcaatacgta
    17881 cgcggagaca tcaaattcga ttccttagaa gaattgaaag cccaactgga gaaagacaga
    17941 tgcaccgtaa ataatttatt ataatatgga aagatattac gaagcgattg atttattaaa
    18001 aggcatgatc tcccgtccgt ctttcagccg ggacgagacc gccgtagcgg atttcctgca
    18061 agcagaatgg caaaaggccg gacaaaaggt gttccgcaaa ggcaacaacc tgtggatcat
    18121 cgccccggat ttcgatttcg gtaaaccgac ccttttactc aactcccata tagacaccgt
    18181 caagcccgct tccggttgga ccaaagaccc gttcactccc gaagagaccg aggatgatca
    18241 attatatgga ctgggcagta acgatgccgg ggcgagcgta gtctccctct atgaagcctt
    18301 ctgtatctta agcgagaaag aacaacctta taatctaatc ttccttgcgt cttgtgagga
    18361 agaggtatcc gggaagaatg gcattgaaag cgcattggcc gagcttcctc ctatctcctt
    18421 cgctgtcgta ggtgaaccca cgggtatgca acccgccgta gccgagaaag ggctaatggt
    18481 actggattgt accgctatcg gaaaggccgg acatgccgca cgcaatgagg gtatcaatgc
    18541 catcactcta gccatgaagg atatagaatg gttcagcacc tatcaattcc cggagaaaag
    18601 cgacttcctc ggaccggtga aaatgactgt caccatcatc catgccggta cgcaacacaa
    18661 tgtcgttccc gataaatgcg aattcacggt agatatccgc accaacgaat tttatacgaa
    18721 cgaacagtta ttcgagctaa tcaaggaaaa ggttcattgc gagatcaagg cccgcagctt
    18781 ccgccttagc tccacccgca cggatctgga tcatcctttt gtgcgacggg cgatcttgat
    18841 gggaaaagag cctttcggct ctcctacgct tagcgaccaa gccttgatgc gtttcccctc
    18901 cgtaaagata gggccgggaa actcggcacg ttcccattcc gcggacgaat acatcaaggg
    18961 accggagatc cgggaagcga tcgataccta tgtaaggtta ctgaatggat tacaactata
    19021 gcttatgtta aaaaagatac tggggacaat aggctcgcgt tatctgatag ctttccttaa
    19081 cctagcgctg atcttcatca acgcaaaggt gctgggaatc gagggcgtgg ggatgatcgg
    19141 gttgatcgtg gcctcggtaa atatagcggt aatcgtcaat gggattttat gcgggaatac
    19201 gattgtctat ttcatgaacc gttactccat gcggacaatt ttccttcccg catatctgtg
    19261 gacacctatc ggctcttccc tagcttgcgg cttcatgtat cttactgggc ttttacccac
    19321 cggctatcgg ctggatatct tcttgttggc gatcttgagc tctacggtaa acgccaatgc
    19381 ccgcttcttg ttgggtaaag acaatatcaa agggtttaat ctcacgttta tattgcaagg
    19441 aggactgcta tttttcgtct tactctattt ctattatata ttgaagcgcc cggacgtacg
    19501 gtcgtatgtc tggggattat atgtcacgaa cggcatagcc tttattgcca gcctatcgat
    19561 gcttgttcct tatttcttaa aggagacatc ccggtcttcc ggcaaatcgc tctacggtct
    19621 attaaaagaa atgtttgcct acggcctgtg ggccggcgcg gacgggttgg cggaaacctg
    19681 tactacccga ctcaattatt tcttgataca acgtttcgcc gggttgggaa gcgtaggctt
    19741 gctagacgct gggaccaaga tctccgagag cgtatggaat attagtcgca gcgtaagttt
    19801 catcgaatac agtagcgtgg ccaagacctc agaggcaacg gaacaaaaac gtattacctt
    19861 acagcttttc aaattgacct tttgcgcttt agccctcgtg atgggatgta tcttattggt
    19921 accggaatgg atatatacgg attatctttt cagcgccgag ttcaaaggca tacgtaaagt
    19981 gataggcgga ttatcgatcg gaatcgtagc gttaggctgc aacagcatca tcagccatta
    20041 tttcatcggc agcggaaaga tccggtacag tacggcaagc tcgtgcgtag ggcttattgc
    20101 cttattaatc tccggcttct tactcatccc gtcttacggg gtcgtaggtt ccgctatcac
    20161 gaccagtatc gcctttacct ctatgctggt tttctcattg acggtcttct cccggcaaac
    20221 acttacacgc tggaatgagt tccttccgaa caaaaaagac ttccaagctt gcagaattca
    20281 tatacaaaaa tccttgtaat tctatcacga attttatcga taacgctatc aagttcacag
    20341 aaaaggggac aattacgctt gaaatgattt cgtgcaaggt acaggtctcg ggttatcaaa
    20401 acatggactg taccttataa acaaactcca tccaaaccca ataacggatc gcttttccta
    20461 agaacatgga gatcgccacg acccatatat tagcccgcaa gaaacctaga gcgacagcga
    20521 taaaatcacc gataccggga aggaaaacaa agaagcccat ccaagagcct tttcccttga
    20581 tccaatcctg caccttctgt agtttcaccg gatcgagttt caggtatttc tcgatccact
    20641 ccacctttcc caacatcccc aaccaatagc aactcattcc acctaagaaa ttaccaagcg
    20701 tagcagcgat catgcaaggc caatatgccg aacccgccaa taatacaccc gtcaatacga
    20761 cctcgctgct aaacggtaag atcgtggccg ctaagaaaga ggcgataaac accccgatat
    20821 acccgtaggc tataagaaat tccatatacg tatcattaat aatgcgataa acatagctac
    20881 cgagagatgg aacagccaaa agatatattt cccccggttc accgtaaaga aatgggcgat
    20941 caggatagac gccggtacac aggccatttc cagaaattcc tcggacgatt gctcatagat
    21001 aaagaacaat ccaaacgacc aaatggccat gacaatcaga aaagaaagaa actgacgagt
    21061 acgcaaatta tcctcatact catgtgtaac gatatttaat gaggcaatga tcgttaatcc
    21121 cgccactaaa acgatctgta tccaatctat aattcccgtc cctagtaccg caaggaaacg
    21181 gatcttgaat aaggaggtga aaggtatggt aaatgccgtg aaatcccgtt cccagacaca
    21241 ccatccgaaa acaaaccaat aaaccgtcaa gattccgaac aaggaagcga caaatgtccg
    21301 gatattcaat gtcctgaaat tatacattcc caaccaaaac agcggcaaga accaaaggat
    21361 gtgtatccac aacagacttc cgatactgat aatcaaggat gcgttataag ccttatccgt
    21421 agcgtccggg tcatgataag aggtaaataa ctgataaagg gccaatatca aacaaaacac
    21481 cccgacagat gttgatttca agggaaagaa atccgggttt gtacttgtca acaaggcata
    21541 gaagagaaag ggaagcaatg tcttctcacg aatcaacatc aacgcatagt ttacccgatg
    21601 caccagaaac gcaccaccgg ccatcagcaa aaaaccgatc aaataggtaa acaacttacc
    21661 cggaagaacc agacagaggg cattccataa aggaggagcc gtcacctctc catacacggg
    21721 atagcctacc gaatccacat accccacgat ccaacaaaaa atacaagcgc aaagcatgta
    21781 caaatgggtc ataggtgtcg ctatagtata tctacgtccg taatatgaag ttgttcctct
    21841 tgccataatc ttatcttagt gtgaaaatac ggtacctgcg ttagtgcaag caccggagcg
    21901 acgttcgtag tgaacgccga ccggtactca ccgtaaacgc cgactgacgt tcactgcaaa
    21961 tgccgaccgg cgttctcgat aaacgcaatt ataaatcaaa cccgatatcc cgacggaaat
    22021 acttcttatc gaaatcgatc tgcttagctc cggcgaaaga ttgggccaaa gcctcttcct
    22081 tagtagcccc atacgaactg accgcgatca cacggccgcc attcgtcagg atctggccgt
    22141 ctaccagctt cgttccggca tggaacacta tattgttcga ggatacgcca tccaatcccg
    22201 tgattacctt attcttctcg taagcctccg ggtaaccgcc gcttaccaac ataaccgtaa
    22261 ccgccgcacg agggtcctgt accaatgtac gagccgctaa atcgccttcc gctacccctt
    22321 ccagcaaatc aaccaaatcg ctttggatac gaagcatgac tacctctgtc tccggatcgc
    22381 ccatacgaca attgtattct atcaccatcg gctcattctt cacattgatc agacccaaga
    22441 agatgaaacc tttataatcg atatactccg ctttcaatcc ctctacggta ggacggataa
    22501 tacgctcgtc caccttcgcc ataaaggcct catcagcgaa aggaaccggg gaaacagctc
    22561 ccattccacc tgtgtttaaa cccgtattgc cctcaccgat acgcttataa tctttcgcta
    22621 ccggaagcac cttgtaatcg ttgccatccg tcaagacgaa tacggagcat tcgataccat
    22681 ccaagaactc ctcgatcacg accgtcttgc tcgcgtcgcc aaacattccg cccagcatat
    22741 ctcccaactc tttcttggct tcctccaagt tatcgataat cagtacccct ttaccggcag
    22801 ccaatccatc cgctttcaat acataaggag cggaaagaga ttccaagaac gcatagcctt
    22861 cctctaggtt ttcagtggaa atactcttat aacgagcggt cgggatatga tgacgcatca
    22921 taaacgcctt ggcgaaatcc ttgctacctt ccaattgggc accttcccca ctcgggccga
    22981 tcacggggat ggagcttaat gcctcatcct tcttgaaata atcataaaca cccttcacca
    23041 atggatcctc gggacctacc acgaccatat tcacttggtt cgccaacgca aaatccttga
    23101 tagcggcaaa atcatccgct ttaatatcca cgttggttcc taccaacgct gttcccgcat
    23161 taccgggagc gataaataac ttatcaactt tcgggctttg agcgatcttc caagcgatcg
    23221 catgctcacg cccaccagag cctaataaca atatattcat atctcttcta attttcaatt
    23281 ctcaattctc cattttcaat tcccaaggta gtcatcgaaa tacctcgtaa tcttctcatg
    23341 caaatgcgga cggtccttac cggtcacatt atgctcatgg cgaggataca caaagtaatc
    23401 cggatacgta tcagcctcta cgcaagcctt taagaaacca aggctgtgtt gccacactac
    23461 caccggatcg atatccccat gtatcatcaa cagatggcct ttcagattac cggccttcag
    23521 tttcaggttc gcgttcttat aaccttccgg attatcctgc gggcgatcca tataacgctc
    23581 gccatacata atctcgtaat tgctccagtc gataaccggc cctccggcca cgcccacctt
    23641 aaagatctcc ggataagtca gcatcaagtt cgttgtcata aaaccgccat aactccagcc
    23701 atgtaccccg atacggtcgg catccacata aggcaaggat ttcaggaact cgacaccctt
    23761 cacttggtcc gccatctcat tgatacccaa attacgatga atcacgctct caaaagcatg
    23821 tccacgattt gccgagccgc ggctatccac ggtaaacatc acataacctc tctgtgccat
    23881 atagaggtcc caaccacgag ccccgttttg ccagtcgccc gtaacaagct gtactttagg
    23941 gcctccatat acatagacaa tcgtaggata cttcttcgtc tcatccaaat ccggcggtaa
    24001 agtcaaccgg taattcaagc gagtcttacc atcggcggca aggatatgtc caaccttgat
    24061 ccggggcatc cgatacaatt taaagggatc cggagcggaa agtaaggtag aaatcacctt
    24121 agcgtccttt atacggacta aatcgatatc cctcggggta gaaggagaac ttacataatc
    24181 aatcgcatat tcgccggagg gactcagcaa ccaacggtgc acgcccactt tccaactcaa
    24241 gcaattcatg atatcacccg ttctcaaatc cgtctcccaa atataacgtt gcatccccgt
    24301 tccttgcata ttcggagata cgggatgagg tgccgttccc tcgaaaatca ccttatttcc
    24361 gtctttgcta aagcctagca ccttggtaac cacccattcc ccaccggtta gcttccttaa
    24421 ttcctttcca gtcgtatcat acagatatag atggttatag ccatccgcct cactctgcca
    24481 gataaactta tccggatcgt tcggcaagaa aagcacggga tgctgcggct ccacataaca
    24541 acgatccgtc tcggtaaaca gatcagcctc tttctttccc gtcaaggcag agtaccgcac
    24601 caaatgcatc tcgttctgct cacgattcaa ctcagcgata taaatactct tctcatccgg
    24661 actccaagcg atatttgtta aatatttctc tttcggcaag cctgtctcca accaaaccgt
    24721 ctgcccggta gctacctgat agacacccac cgtaacctca tggctcttca ttccagccat
    24781 cggatattta tgaggaaccg gcgtagcgca acgagtatcg atattcacca gcgggtaagc
    24841 ggtcaccata cgcttatcca tacgataaaa cgctagagcc gagcctttag gagaccaaaa
    24901 catacctttc gtaatcccga actcccgttg atggacagcc tgtccgcata cgattccatc
    24961 ctgtgtttca cgtgtaacaa tcgtatttcg tccatccggg gataaaatat gcacattgtt
    25021 tccctccgta aaagctaagt tattcgtagc cgggcaaaag tcataattcg cccagttatt
    25081 cttcaaagca taatcagcga ctaccttatt tttcttatag tcataatgaa tccggtgctg
    25141 tttgctagta aaagtcaaga ccgaacctct ttcatagggc accgaaaagc taggcaaaga
    25201 accaaccgtc tgcagatttg ccgccgtcaa ggccccattc agtctttcca acgaaaaaag
    25261 gacctcttct tttttccccg gcttagctcc taacacgcta tctcccttaa catataagta
    25321 ctcgtccccg caccatcgta actgtttcaa gtcacgaggt acgaagcggc tatacgtctt
    25381 ccctccagga atcaagtcgt gcaaggagag ttgcttatct tgggcggtaa tcgacatcgt
    25441 taataaaatc agacataggc ttatgaataa agatgattta atcctcataa tcatcatacc
    25501 ctctccgttt tataggcttt ataggtttgc taaatgggcg ctttccatcc cgcttatgat
    25561 cgccaaaccc tttcttacgg tcatcctcat cccgataacg cattttcaca ggacgttctc
    25621 cttttggctt gatcggctta cgaaccgggg catctacgaa tttcttgcgg accggacgat
    25681 cctctccccg atcctctcca aagatacgtt tccccggaat ggaagcgaaa cgctcctcat
    25741 catcctcgct atgggcagcg gcgaaacgac gctccggacg atccacacga cccgtacgga
    25801 agtttggacg atcattgcct ctacgctcga aagagccttc cgatctgtgc ggacgctcct
    25861 ctccatcctc attcaatgcc tttttgaagt ccttattggt tccctcaaat aactcatagc
    25921 aacggtattc gcactccaag gaaccgttca tcaatttgat cttctcgctc gggcgcaagc
    25981 cgatcttatc gaaacattca tctttatagc tcaaaatcca agccttatat cccatgaaca
    26041 catgtttcaa acgctcgccg atcatattat acaatcccaa tagatcacga gatgatatac
    26101 gctctccata aggtgggttc gtcaccaata tacctggctt cggagcctct gtatattgtt
    26161 ggaacggttt caccttcaga tcgatatatt tcatcaagcc agcgctacgg atattctcca
    26221 aggcgatatc gatagcggct tgggaaatat cggagccata gcaatggaaa gcgaactcac
    26281 gctccccgct ctcatcatta taaatacgat cgaacaattc ctcatcatag tccacccatt
    26341 tctggaaagc gaactctttc cgatggatac ccggagcgat attcaaggcg atcatggcag
    26401 cctcgatcaa caatgtaccg gaaccacaca tcggatctac gaaattagat tctcctttcc
    26461 aaccggtttt taggatcatg ccggcagcca acacctcatt caacggagct tccgtttgat
    26521 ccacccgata accacgctta tgcaaagact cgccggagct atcgatagat aaggtacaat
    26581 cgttatgcga aatatggata ttgatatata agtccgggtt attgacacga acggacggac
    26641 gcttcttgaa cttctcgatg aaataatcca cgatagcgtc tttcgtacgg taagcgacaa
    26701 acttcgagtg attgaaatcc tcggaataga tcaccgagtc gatcgcgaac gtcttgtcca
    26761 gcgacaaata cttctcccac tctacctttt tcacctcttt ataaacggta tcagcatctt
    26821 tggccttgaa atgataaatc ggtttcagaa tgcgcagggc agtacggcag tggaaattcg
    26881 ctttataaag caattcctta tcacccgtaa aggaaaccat acgacgaccg atctgcaagt
    26941 cgttggcacc taaagctaat aactcctcgg ccaagatctc ttccaacccg tatagggttt
    27001 tggccaccat ttcaaatgtc tcgctcattt taattgaaaa ttgagaattg agaattgaaa
    27061 attattccca attgcgtatt acgttgttta ttattaatta ttctcatttc gctctctgac
    27121 atgcttcgat ctccttccgg ctaccctctt gataattttc aattctcaat tttcaattgt
    27181 gtaaccgtac tccctgccgg tacatcctcc gctatccaga cgttaccaca tatcgtagcc
    27241 cctctgccaa tccggatttt accgattaag gtggaattag aatatactgt cacatgatct
    27301 tccaagatag gatgacgggc tacgccacgg atagcgttac cgttctcatc ggggggaagt
    27361 ttctctcccg ccaagctgac gccctgaaag attcggacgt aattgccgat cacgctcgtc
    27421 tcgccgatca ccgtacccgt cccgtggtct atcgagaaat gatgaccgat cttcgcgccc
    27481 ggatggatat cgataccggt ctcggaatgt gccatctccg taatcatacg aggaatataa
    27541 ggaaccccga gcttatacaa ttgatgggcg atccggtaat taccgatcgc ccggaaaccg
    27601 ggataacaaa atatgacctc acctagattt tgagcggcgg gatcgccatt gaaagtcgcc
    27661 tccacatccg tagccagcag accgcgaatc tccggaagcg tagagatgaa agcctccgaa
    27721 atagcctctg cctcagcgga gatcttttct tccgggcaag tcacgcaaga tgtatctgcg
    27781 aaacaaagtc ccgcataaac ctgcttggat aataaagaat gaagagtctc aacatttacg
    27841 cccgtatgaa aacggatcgt ctgtttactg atacgggcat tcccataata accggggaac
    27901 aggatcgcac ggcatagatc gatgatctct ttcagcacct cgcccgaggg cagcgcctcc
    27961 tcatccctgt acgcatggaa caattgttta tacgatgcct catccgatag cttctccacc
    28021 gtatcgccca atacgctact atgcctctgt atatccatta tttgcggaat attctttata
    28081 atgcgcaaaa atagtatttt atttgagaac accttcacga agaggcatca aaaatacagc
    28141 caacgactaa tattacgttc tatagcgcta aattccacgc caacctttat caacttacgc
    28201 ccatccgcct gatagagtta caaataaata atcttcatat cgaatacttt accacatcca
    28261 atgctccact ttcatcaaga gccaaggcga ccagaaaacc atcggaaggg tctacagcaa
    28321 tcctctttat tgaacgatca aaattcaatc gtttctttaa ttggccgtcc caagaaagaa
    28381 ccagcaatgt ggataaattc gaaaaatcca cagaaccatc gtacaagcaa tacacatacc
    28441 gatccgtacc gaatatatcg ataaagcatt ttgtcgttcc aagaacatcc acttgggtat
    28501 cattcttctt cagtaaaggc acgataggct ccttcccata cgtaaagctc ctttgataag
    28561 ttcccttcaa atcgtaaaaa tcaatttggt tgaagaaacg caaggcagca accacactgt
    28621 tttgccgctc attcacacaa agattaggca aataagcgac gtgcttacaa gaacgatacg
    28681 ttcttgctac ttttggtggc tccacccaat aaattccctc ttcccgattc gcataacaga
    28741 aaggaccata aacatttttc tctacgatcg gaaccgcata aacttctttc gtggtgacat
    28801 tataatgcgt agagggaaca agttcgggta ttagtatata tttccgatca aaacgcaaag
    28861 aatccgccag cacctgcatc ttattaaatg taagttggtt atccacgatc cagaactcat
    28921 cctttccggc gggttctttt gtatttgact tcataaactc cggattagag aaataagtgg
    28981 caccatatcc tttcaacgca aacgcatgca ggtgcgacaa atcatctttg tcgaatactt
    29041 gaatgatcgt atcacaccca cgagccaaca acaccaaata agactcggta agaccaatcc
    29101 catcatagca tacaccagaa tcccctttca ttaacaaatt tccctccagc cgtttttctt
    29161 ctctttccgc atcggaacaa gcgagaagaa acaaagcgaa gaatacaata atcccataca
    29221 atactctcat gacctttcta ttttaaataa acataagatc ggattatcgt cctgtgtacg
    29281 attctccgct atccgtctca aatcctcata atgtatctga ttacgcaaca gcaccgtcga
    29341 actgatcttc ccgataaaat aatctttata cactccgcaa ataccgtaaa agcctgtcaa
    29401 ccccgtagcc cttatgaagt tggggaacgc atacgagaat gcctctttcc tatccttgtc
    29461 ataaaatccg aagtaagtta ccttatcgca catataggtc gcatgcagga tccgttcggt
    29521 ctccagcagc ccaaaagaat ttacatagcc ggagcgaaac agatcgccag agaaatctct
    29581 cccgcctctc cctttctcct tgacatactc gataggaggc atacttttat ctccgaagcg
    29641 aactttataa gcaggctcca acatcccgtc cttcactttc catacttcgg gggtaaaggg
    29701 gaaatgcgca taccaattcc cagcaaaggc atgcaacgtc ttgctcccat tgatcgtatg
    29761 gccggacgtg aaataagccg gtcccaacaa tgcgtcttgc tctcctttcc tgtccgtggc
    29821 tttcagatag aagttttccc tttgcggtgt cgcaaatccc aaaggataat accaaatcca
    29881 attctcctta tccaaagggg cgcagtccac aaaataatca gctacatctt gcgtggatat
    29941 atattgatag gtatccagat cataacgcaa taaggccgtc ccaccaaaat ccaccaatgt
    30001 caagattcgc tctttctcat ccacgaaaaa gtgagttaga taaagatact ctttcggccc
    30061 ttgtccccgc aagcctacac gagtaataaa atttccttga tcactgaata caaaaagcgc
    30121 atttatctca tcacttctat cgaatacaaa aatacgatcg tccacccagc aaacccggta
    30181 gagatctttt aacagcacgc tatccttcgt ctccaaagga atgaatctgc attccaaatg
    30241 ttcctgcaag ccaaccgtac aatcgtttcc gaaatccacc acgtcccact cttccgatcg
    30301 attctcgcat gcggtcaaaa tggaagccac acttatcatc actaaataat atagttttct
    30361 catgtttttc atattagatt cagaccgcta atatacgtaa ctttttgaaa tacgccaact
    30421 gcacaagttt tcctaagcgc acaatcggaa ttcacgagaa gtactacttc cttggcctat
    30481 gaagtatatc tcctagagca gttgaagtat atattctaca aaggaaggag tagtactggg
    30541 aaaaaggcct gttgggatat aaccctaaaa actttcgata attagaaggg gatacagtgc
    30601 ttattttcca catagttatt gtacattttt ccaaatgcat ttaaaacctc attatctgtt
    30661 tcccaaaaca cgtacgtgtt ttcacaaatt ctcgtacgtg tttccggaaa aacacgtaca
    30721 tatttttccg gaaacatcat caacttttta tcagcctgat tataaagaca ttatcaatac
    30781 gtatatttta aatacttact gtatttttca ctatcaacaa aataccttat ggttatgatt
    30841 tttgaagccc caagaaggct ttatttacga gcttatcgac ttccttatac agccgttgta
    30901 tttcctttgt atccaatcca ttttgctccc actccgtctt atgagcgtcg aataaatcga
    30961 aaatccggtt ctctaccgca cgaagctgtt ggatataacc agattggtca tcattccata
    31021 acagttgcca atgcaaatac ttttgaccgt tgccacgatg tatggagtag acattcttct
    31081 gtaattgaac ggagtaccaa tctaataggg ctgttttata ggatacgtcg taagtaacca
    31141 aagtgctttg ctcctttccc attttcaccc aaagaggaat agcgacagag gtaggaggat
    31201 atcccaaggc agtccacatc gttgtcaatt ccggattcat accggatttt acgccttgga
    31261 ttacgataga agccgtactt tctagacggg ggatgaaatc ctgctccaca aaccagcctg
    31321 tacgattgtt cggactttgt cccttgtcca tcaaatcgat atccagcaag ctattataaa
    31381 aagagcggga agcctgttga aagatacgct gaggagtaaa tccttcgttc cgcatttcct
    31441 taaagatctt tttcgcgttc tcataacgta catatccttt gccttcatcc gtacgcccct
    31501 cgaaagagaa attcgtataa atcaagtaac cttccggcgc cagattcgga tcattcgcgt
    31561 ctttcttata atatcgctca ttattcgtct cataataagc cgcgccacca taagcatcga
    31621 tcactccgaa attagcctcc acacgcatcg ggcgaggcaa ggtatccaag aaatgctcga
    31681 aatcctgcac cgtcttacag actctcaagg cttttcgcat caagtttccc tcctgatcca
    31741 tctcctttat atcatcgtct ttcaagttat aagaagccgt attcatgata gagaagcccg
    31801 tctcattgct tccggtccac acggctccct ccggatcatc gctatttacc agccccagaa
    31861 aacgataacc accttcgtca aaataaccga tatggttata cggagcgccg gtatcccggt
    31921 gtttccacat caacggacgg ccatcgagag tagcctttcc agtgattata atggaggtac
    31981 aagccttgtc aaccaccgga aaacaaagac atagaacaaa taaaagaagt agttttttca
    32041 tatcatttat tgatttaata agatttctta tgaggagcgc caaattcctt acagctgacc
    32101 tcgtctatat ctaccgtcca aatcttcacg ttacggaccg ccggatcgct ataacggaaa
    32161 gtcttatcgg aatattgctt catgataata tccaaggctt ccaccttctt gtcgaaatcc
    32221 tcttcgtaag cgacctttcc ccaagcgatc acgctcttcg aacgcatacg gtagctacaa
    32281 gctacctccg gatgctggaa aaccaaggca tggtcaatac taaacgtaat acagactttc
    32341 ggattacgtt ccaatataga gatgcttcgt ccatcctgcg ccgagtgtaa ataaatcacg
    32401 ccatccttat aaccgaaatt catcggcaat acataaggcg ttccatctgt atccgccatg
    32461 ccaacgaagc aaacatcgct ctggcggata atcgattcga tctgttcctt gtccgtgtgt
    32521 ataagtgtct tcatattcct tatgtttaaa tctaacttga tgcaaaatta aaaaaatcat
    32581 ctgtttctgc aaccctttat aacccgcact cgtctattaa gaaaagaacc taaaaaatta
    32641 aagacgatga agacgagagt atcacttttt atattctgta tacagatggt cgcggtttgc
    32701 ggattcgcag ccgacaaacg tatcgatgga aatgggaacc cggaaacccg ggagataaag
    32761 attagcgatt acgacgagat cacgttcgtt ggctccgctg atttcgagta tgaacagtcg
    32821 gataaagcgc cttatctatc cgtaacgatc gatgagaact tatttgatta cctcgtgacc
    32881 gaagtagaag gcggtacgtt aaagatctat ccgaaatcta tcaagaaagg ttttaataat
    32941 aactcctacg acttgaggcc gaccgtctac aagataaaat ccaactccaa ggaactaaaa
    33001 gagttgaata cggtaggttc cggcagtttc attatcagca aaccgacgaa agtaaaccgg
    33061 atggagatca atatggccgg tagtggaaac gttgagttga gaggccccgt aaaaggttac
    33121 aagcttgaat gtaacatggc cggtagcgga aatatcatcg ccaaggatat acagctggac
    33181 aacctatctt gcagcctcgc cagcagcggg gaaatcgagg taataggaac cgtagatcgt
    33241 gcctcattca atgtagcggg aagtggtgag attaaagcct ttgactgcca agcacgtaaa
    33301 gcagagtgta atatcgccag cagcggcgag atcagcgtat atgccacgca aatcttggat
    33361 gctaatatcg taggtagtgg cgagatccat tacaaaggag atccggagat cagtaagtct
    33421 atcatgggtt ccggctcgat caacaaagtc aaataaacat ttaatacata cgaacgatga
    33481 aaacaaaatt agtagcggta atagccctca tcttttgtgc cttcatggca gaggctagta
    33541 aagtagaagg aaatgggaat ataattacga aagagatatc ggtagataac tatagcgaga
    33601 tcgaactggg tggaaatatc gaatattccg gcaataattt ttggggaaat agaagcaaca
    33661 agaaattccc ggtattcaaa tatacgcatg gacgaagcgc ttccttgaaa attacgatcg
    33721 acgagaatct attcccactc ctctcgatca aatccaataa cggacggtta gctatccgca
    33781 tacaagacgg gacccgtatc aaaccgaccc agtatgtaat cgaaggaagc tcgaagactc
    33841 tgaaatactt aaagacttcc ggcccgatgg attttgaggc gcagaacgct ttttccgagg
    33901 atcaactgga aatcaagatt tccggctcca gcgacgtaaa gttcccacat aacgtgaaat
    33961 tacgattagg tgagttctcg gtatccggct ccggcgatct ggtttttgaa gatttggact
    34021 gcaaaaatct taccagcaag gtttcaggct ctggagacat caccttgaaa ggtaaggcgg
    34081 acgaagcccg ctattccgta tcgggcagtg gagatataaa agcatacgac ttatctgtca
    34141 atgatttgag ttgttcggta agcggtagcg gagatgcccg tgtttatgcc aaggataaca
    34201 tgaacctatc ggtttcgggc agtggagaca tccgctataa aggcccggcg aacgtgaata
    34261 aatcaaagtc cggctctgga tccattcaag gcgcaaattg atcgaacaca cacatttttt
    34321 ttaatacaca cattatcaaa tttaaaaaag ctactagatg tgatatccgg tagctttttc
    34381 ttgctatttt tgtaaccaac tctttattta tagagtctaa attaaaaagt agaatcacaa
    34441 aaaacgatac ttatgaaaac aaaggctatc ttattaatgg tatttttcct aggatgggtc
    34501 actaccggtt gggccgcaga tcatgtaaaa ggcgatggta aattgacctc gaaaaagatt
    34561 tctgtcgccg attataacga gattaaggtg gatggcgtaa ttgatttcaa ttacgagcaa
    34621 tccgatgatc cttccaccgt ggaggttacc gtagaccaga atcttcatcc ctatgtcaat
    34681 atcgaggtga aggatcgtgt cttaaccatc gctttcaaag gagcgaaggt agatcatttc
    34741 acgaagttta tcgtaaagac gaattctaaa tggcttgccg ccgcaaaagt ttccggaaat
    34801 gccaacttca tggtaaacag tccgcttacc ggagacgaga ccgttattaa ggcgaacgcc
    34861 aatagcttgg tgcaactgaa agagacagtt acggtcggta aactggattt gaatgtatcc
    34921 ggtagcgcaa atatggttgt caatcatctg gaagccgaca agatcgaatg tgatatcgat
    34981 ggctccggct ctataacgat caagaaaggt aatgcgaaag aaggagacta cagtatcgtc
    35041 agcagtggtg atatacacgc ttttgggtta gcggttcctc agctaagttg caaagtaaca
    35101 ggcaatggct tagcggaagt acatgctacc gataatttaa aggccaacgt aatcggtaaa
    35161 ggaaatatcc gttataaagg cccgacagca gttcaacaga gaataatcgg taaaggtacc
    35221 gtagaagaag taaaagaatg aaaacaagaa ttatatacct atgtctgctg gtgatctttt
    35281 ctacgacagg ttgcatcagt aagaatgctc gaaaaggtat caatgggaac aagaatattg
    35341 ttacccgcac cattcaagta gatgatttcg aggaaataca tctagggtcc aatatcgaat
    35401 cggcgaaagg catcaatccg ttcaacaaga agaaccgtgc gatatgtaat tacacccaaa
    35461 cagatggcgc ctcctcgttg gagatcagca tggacgagaa tttgtttgac ttattggata
    35521 tagagaataa ggatcacaaa ttaatcatca aggctaaatc cggcaagaag atctgtccga
    35581 cccatctggt attgaacaca agttccaaga acctgaagga agcggggatc agtggcagca
    35641 tcgactttat cgccgatcaa ccgctacaac tgacaaatac gtctttttat atcagtggcg
    35701 taggcgacgt gaaattagct gatttatctt gtgatacttt caaggtagct atatccggag
    35761 tcggcaatat ttacttgaat ggaaacatca agaaaggcaa atactccgta tcgggtgtag
    35821 ggcacgtata tgcgttcgat tgccccgttg aggatctgga atgcgaagtt tcaggtgtag
    35881 gaggaatgga agtgaacgct acccagaaat tagacgctag cacttctggt gtgggaagcg
    35941 ttaaatataa aggcaatccg gagcatacgc agaaatccgc ctccggtgtc ggaaaaatca
    36001 aacaagcaga ttaatcatcc caaaaatcaa ttaaatgaaa aagatatcac ttttattcct
    36061 tatatgtggc ttatttctag taagcagctg tatccctaca caaaccataa aaggagacgg
    36121 caatatcacc acggaaaata tcccggtttc cgagtatgac tgtcttgagt tagagggagg
    36181 aggcatggtc gtgaattaca cgcaatccga cgctcctgaa ggtttggaaa taaagacaga
    36241 ccggaatatc ttcgagaaat atgagtttaa tgtagagaac cataagctta agatccgtcc
    36301 gaaaaaagaa ttcaggaaac atacgaattt ccgtccgacc gaattcatgg ttacggccaa
    36361 ctcccgcaat ctaaagaaac tagcggcggc aggcagtacc catgtaaata taaattcccc
    36421 tctacaagcc gaggagttcg aggcaggatt agccggtagc gggattatcc aattccacga
    36481 tacggcctct tttacaaacc tgaagataga gatcgccggt agtggagatt tcgttggcca
    36541 taaagtgtat tgcgaggaat taaatgggga tatggcgggg tccaacacga tcgttctagg
    36601 gggaaccgta ggcacagctg agttctcgat cgccggtagc ggtacagtac gtgctttcga
    36661 ttgtaccatg gatgagcttg agtgcaagat tgccggtagt ggagacatag aagcctctgt
    36721 cgtaaacaaa atcaaggcag agatagccgg tagcggttcc gtaaaataca aaggagatcc
    36781 ccaagatatc caaaaaaagg taatgggctc cggtaagatc gagaaggtgg agtgattctt
    36841 acaaccaccc ctccttttta taccattcga tactttcttc caagccttta cgtaaaggat
    36901 aggccgggat aaaacctaaa tcatcttgaa gaggcgtgac atcgcaaatc cagttacgct
    36961 gcttcaagat gatgtattta tcactattta gcgtcatact tttcttcaac aacttaccga
    37021 tccattctga acagtggcaa gcgatacgca ccaatcccag cggtatacgg gcatgcaata
    37081 cccgcttctt tcctaagata tcttgtatca tacgggcaaa agactcatcc gtgtagacat
    37141 ctccgtcggc tacaaaataa tgccggttct ctatctcttc tttctcaagg gaaaggaagg
    37201 ccacggtcgc taaatctttt acatagataa acgtgattcg ctggggaata gcacctacgg
    37261 cgaaatcgag ccccgacttt acgctttgta tttccatgaa ataatccttc tcacccggcc
    37321 cgtatactcc tgtaggccgc aagatcacgt aaggaaaata ggtttgttta cggatgtagt
    37381 tctccgcctc tagcttactt tggccataag ccgtgtccgg ccgctgcgga tcgtccaagc
    37441 gtatcgggcg gaaagtcttc tcgtcgcctc gcccatagct gcttaggctg ctcatcaaga
    37501 ggaatttctt cggtttgcag ccggcggcgg ctaaagcctc gataaatcga tgcgtattct
    37561 cggcgttcac acggaaaaag tttcgcttat ccaatgtctt cgtcaacccg gcgttatgga
    37621 tcacataatc ccatgcccca tgctcacggg caaagtctga gagttgagcc gtaagcgctt
    37681 cctgatcgcc atatttcaag tctatgaaat gaatccgctt atcttgcaga tgcgctttac
    37741 tgctacccgc acggataccc gcccacgtct catagccacg gcgaagcgcc tcctctacca
    37801 agaaaccgcc gataaaacca ctcgctccgg ttatcaatat cttcatatcc ttcatttttc
    37861 tttcatataa aatgtataat aataccacag cagcccgatc caattcagga acaggatcgt
    37921 cagcatccaa agaatctttt gtttcttact gatgaaaggg ttttgcgata cggccttaca
    37981 tccgaacagg attacggcaa tacctacgat ataaccgatc tccggcaagc ttatccagca
    38041 aatgatttgt ggtatcataa aaatagagtt attcgtgaaa aagaattatt cgtgttggtg
    38101 tttcttcaag actcggtgcg gcaagtcacc atgccccacc aactcgatcg ggcaagcgta
    38161 tttctcgccc aaccattcct cggagacatt cgctcccgga tgataatgca aggtctcgtt
    38221 tacgcaagcg atattcttca ccatcgccaa aaccgtgccg atgtcatggg aaaccaagat
    38281 gatagcgctc tctttattga tctcttccaa gagctgataa aaacgggact cgaatcgttt
    38341 atccacatac gaattaggct catccaagat caatacctgc ggacgggaga caatagaacg
    38401 ccccaataag acccgctgca actggccacc ggaaagctca ccgatggccc tgttcgccaa
    38461 ctcctccaat cccatctgta cgatcacctc gtctacacgc tctctctgag accgattgaa
    38521 tgaacggaac aagggtttct ccgcggataa accggaagag atcacttccc gtacggagat
    38581 cgggaacttc ttatcgatct ggctcatttg gggtagataa ccgatcttca aggaaggaac
    38641 ctctacatcg ctatcataaa agcggatcgt tccggtaata ggaggcaaca ggcctagtat
    38701 caccttcaaa agcgtcgttt tcccgccgcc gttcggtccg atgattccca agaaatcatt
    38761 tttccacaca tccagcgtta cgttacgcaa ggcgatctta ttaccgtatc cggcggtaac
    38821 ctctctcaac tcaatcagct tgtccatcgg ctaacgattt tgcgatatga atcatttcct
    38881 tactccaatc gtaatccagc ggattgatcg ggatcagacg gcaacctgtt tctttagcga
    38941 tcaactcggc gttcttctgg tcaaactccc gctggataaa cacgactttc gcattatgtt
    39001 cccgtgcggt ctcgaccagt tcctttaatt gtgcgggaga cggttctttt ccgtccatct
    39061 cgatgcaaag ctgggtcaag ccatattcgt tagccaaata ggtcagggcc ggatggtaaa
    39121 taataaatgt cttattgtca agagaatgta acaaaccgga aacggtcttt tccgtctctc
    39181 cgatttcttt cgtcagttgt tcataattcg cttggtaata ttccttattc tccgggtcca
    39241 aagacacaaa ggcatccaaa gtgttcttgg cgatcacctt cgctccagag atagagctcc
    39301 acgtatgcgg atcgacgcct ccgggatgat gatggtggtg gtgatcatgt tcctcttctt
    39361 cctcggggct tttaagtaaa tcaattcctt cggacaggtc aaaaaccttg agtcccggat
    39421 tattattccg gatattatcc atccaagcct gttcgaaccc aatcgatccg atccttaaat
    39481 agccttggct tttacccacc tgcaccattt gctgcggtgt aggatcatac gtctccggac
    39541 tttgccctgc cggaaccaca caattaatct taaatttatc tccggctatc ttctccgcaa
    39601 aataccgttg cggctcaatc gtcacggaaa cgatcctctc atctgcccgc ttatcgccgc
    39661 aggccataag tatcaagacg aaaagagctg atatcaatac cttaaattct ttcataccac
    39721 atatatattt tcgcaaaggt aacgaatatc gggtaataag gcagcaagga gacgattcaa
    39781 agttatcagg aagcagtctg acaaaatccc cgtattacaa ccgataagta ataatacggg
    39841 gatttatagg gaaaaaatag gctactctat ttttactcgg ccagccattt attcatctgt
    39901 gtaaggatcc gctccttcat atcctccggc atattgccga tacgggcacg atggctacct
    39961 cggggctgga tatagatttg ctcgttcttc ttgcctttga aagcgggaac catggctgcg
    40021 ctccacgggt cgatctcgcc atagatgaag atcattttcg gatcgttgtc tttcaagaag
    40081 ttatagatct tgtggtacag agccggacgg aagtctactt taccgaccag ttcctcggga
    40141 agcatgatac ggttcaagta tccgtgggcg ctatcgatcg taaggtattt cttgaaaggt
    40201 tttacgtcat agccataata accgagctca cgggcggctt gtacgaagaa agagatattc
    40261 ggctggttct cggcgaagta atcaggaccg ctgatttcca tcaaatgatc gaagagcgcc
    40321 tgatcgtcgg cagacttgga agggatcgta cttatcgaag ttccccactg ccaaagagcg
    40381 aatgaatatt ccagtacgca ataatccaat acctcgggca tcgggatacg gaatgtcaag
    40441 ttcttattct tacaatagct ctccaataaa gggagcatat cggacttacg tttcaagact
    40501 tccaattgaa aatcctgtat cttcttgcgt tccgctttcg tacctacctt acgtaagaaa
    40561 ggttcgtggc ggccatcctc tacgccttta cataacggac cgacataagg aacggagaaa
    40621 tccacgtcgt ccgggaaaaa ggcacggtaa agcattgtag tctgtccccc cttactgata
    40681 ccggtactga tccatttttc cggatagatc tgcttgaatg tattgcggac gttatgtaaa
    40741 tcgtacgcag agttctcggc ggtcagataa tcccagtttt taggttccgg cgtcgactcc
    40801 aagaaataac ggtactccac aaacactaag ttcgcgttca atagtttaga tagttcttcc
    40861 tgatatttcg gattgagcgc ataagccgct ccatatcctt cggtcaccat aatggtagga
    40921 cgatcataac ctacatggcc tacgataacc cgttgcgtaa atgttccggc ggcggggtct
    40981 tttggatcga cctgctgagt aatacgtact acatatttct ccggataata atcggattga
    41041 agtttttcaa tgccactaat tccttttagg gaggcaagct tctcttgtaa atctccggga
    41101 gcggccatta ccgtcatcac cgacaggaag aaaagaagca agaagttaaa tgttcttctc
    41161 atggtaattt agtcttttag atattgtatt gttcgtaata atccctcata tttggcgcgt
    41221 ttcaccgccg aatgtgcaaa gatacgatta taatcctcac ggctcaatgc cttgaggtcg
    41281 tcttttttaa gggagagcaa agaaggggtg ggatgaaagg ctgctactgc cgtaggcata
    41341 gcgaagcggt tccaaggaca aacggcttgg caggtgtcgc atccatagat acggttacct
    41401 aaaaggacgg cttgctcaac agggatttct ccacgatgct cgatcgtaag ataagagata
    41461 catttacggg cattcaaacg tttcggccct tccaaggctc cggtaggaca agcgttcaaa
    41521 cagcggatgc aggaaccgca gtgattcttt ttgggggaat cataggtatc gactaccaaa
    41581 gttgtcacga tctccccaag gaaaaagaaa gagcctttgc ccgggatgat tagattcgta
    41641 ttctttccga tccatcctaa accggctttc caagcccaat aacgttctaa cagaggggcg
    41701 gagtccgtga atacacgggc ctcattgttg gagggatgat gctcggttat cgctttccat
    41761 aattggcgaa gtttatcctt tacgaccccg tgataatctt ctccatacgc ataatacgag
    41821 atataaggtt ccgccggatt ccggagaact ttcggataat aattcaaggc tactgagata
    41881 actgatttgg caccttccac caagccatcc ggattgagac gaatttcccg atgattctcc
    41941 atgtatttca ttccagcatg gtagccttcc gcgatccatt ggtcaaaata agcctcctcg
    42001 ctcccggcct tcgctacttc agcgataccg caagcggaaa agcctaattc catagcttta
    42061 tcttttataa actgggagat acccattatt caaaaacttt aaactcgtag ccttctttta
    42121 agagccattc gacagcccgg ggcattgcct cacgcatatt gcgctcggct ttcaaggaat
    42181 cgtggaagac gataacagaa ccattacggg tatagttctt taccacgttg aagacaccgt
    42241 tcggagtcat atgagggcta tagtcacggg tgaccacgtc ccacatcacg atatgataat
    42301 gacggcgaag ccatactacc tgcggaaaac gcatatgccc atgaggaggc cgaaataaat
    42361 tgctgggaat atattcggct gccttctcca cattcgccaa ataattcttc gtccagaact
    42421 tgataccttg gatatggttg aacgtatggt taccgacacg gtgcccacga tctatcacca
    42481 tctggaagac ctcgggatgc ttacgtacat tatcccctac cataaaaaag gtagccttga
    42541 tcccatacgt atccaatata tctaaaaccc aaggggtaac ctcgggaatc gggccgtcgt
    42601 cgaaggtgag atacacacac ttcttctctg ccggtattcg ccaagttacc cccgggaaca
    42661 gtgccctgta aaaccaaggc ggttgttcta taaacatact ttgttagtct tttgccactg
    42721 atccgtacgc catacggtaa ttatcaaatt cctcttgata aggcttagcg aactccggat
    42781 tgtattgttt gcttacacgc aatacctctt ggagaaccgc caagttatga cctaaatcac
    42841 tctcgacaga tgataattgc cccggacgca aacggaaata ccagtttata ctgcgcaacg
    42901 cattgtccgc tataccttta taaaccatct ccgccttctc cttctggccc aactcgtaat
    42961 acagctcacc taaagaaaga gcgctataat ccaacggaac attctcggga ggcaatactt
    43021 ccatcgcctt atccaatacg ttcagtgctt tctcattctt gccctcagcg accaaagcgg
    43081 cagccaactt actgaacaac gcgatacgat agctcttgca catccgcatt acattctcat
    43141 ccaagtacac acccggcgta ttgacaccac cccatttgaa cttattcatc acgttgtcat
    43201 acatcttctc cgtattgatc gaacgaacag ttccctgtgt ctccatcgga acgatctgat
    43261 aagccatacc ggtctgctgg aagtacggat ccaatttcac gaactgatcc gggcttacgg
    43321 taatcgcgta atagatcgga cggttccagt cattcgtctg caacatatcc aagataatca
    43381 actcttgctt acccaagaca tccttgcctt tcaagtcaat cttcatctct ttctgcaaat
    43441 acggcaagtt agcggtatcg atcacgccgg cagccataac cgcagcggaa tctaccccca
    43501 tcgtcaatgt ctgcgcagga atataatcta attcttgatt gatacccggg atcttcttaa
    43561 acttcggatc gttgctacga acgaaatcaa gagcggtctt cagatcgatc gacttatccg
    43621 tcatcgggaa tacataagcg gcatcacgag taccttgcac ataatcctcc ggttgccaag
    43681 agattggaag cggatcggac tcgtacgctt gcttcttcat ttggttgata taccagtcgg
    43741 tttgcaaata gctcgtatta catacacgta catccgtacg gataccttcc acctcctgtg
    43801 cgtaccacaa cgggaacgtg tcattatcac cattcgtaaa tatgacagcg ttcggctcgc
    43861 aagattccaa atagttcgca ccaaaatcac ggcaaacata acggttcgag cgatcatggt
    43921 cgtcccagtt ctgcgcaccc atctggatag gaaccaacaa gcacagtacc gtagcgacag
    43981 aacccgctat caccggagat aacttgccat acttctgcaa tcctttcgcc aaggccgcca
    44041 caccgaaacc gatccatata cagaacgcat agaatgatcc ggcatacgca tagtctcgct
    44101 cacgaggttg atacggcgtc tggttcaagt aaagcacgat cgcgataccc gtcataaaga
    44161 acaagaagaa cgtgatccag aatccctgaa tgcccttctt tccggcataa gcttggaata
    44221 gaagccccaa gatacccaat agaagcggta acatataata tacgttatgc cccttattgt
    44281 tgataatatc gaacggcata tcctcttgcg ggcccactaa agcctcatca ataaacggaa
    44341 taccggttat ccagttacca ttcgagacct caccgttacc ttgtatatcg ttctgccgtc
    44401 cggagaagtt ccacatgaaa taacgccagt acatgaaatt cagctgataa gcgaagaaat
    44461 aacgcaaatt ctcggcaaat gtaggtttca tcaccgtcac catctcaccg caacggttga
    44521 acttcaccgg tgtacctttc acttgtgccc actccttata agcagccaca tgacgtccgt
    44581 cgctactata catacggggg aaaagcatac tcaactcatc cacgtattcg tattccgtat
    44641 cgtaacgaga gatataataa tgatccttct cgtttttatc tttcttaatg acacggctcc
    44701 aagtcggctc accctctttc gatacaggta cgcaagtacc gccttggttc tcacgcttca
    44761 cctcagagac ataggtctga ccgtagatca acggagtctt accgtattgc tcgcgagcca
    44821 aataagtacg caaggtaaag atatcttgcg gagcgttttg gttcataggc gtatcggctg
    44881 tcgcacggat caatgtcaag gcataggatg aataacccac tacgattacc atcaagcaga
    44941 ccaagatcgt attcagcatc ttgatattta ccttcttgct catgaacaaa taagccgtca
    45001 aggccgccgt gaggatcacg gcgatcacgt aaccgctacc gataaacgga atacccaaca
    45061 atacgatcga gaggataaag gatatcttca tccgcaccgg atggatctcg tcttgcatcg
    45121 tctcccagat cgcccagatc aaggaagccg ccaagataat cacgaacgca tatacacccg
    45181 agttatacgg cataccgaac gtattgacaa acaacagctc gaaataacca caaacctcaa
    45241 ccaagccttg tacgacacca tacatcatca agcccacgat agcgaacgac accaataaag
    45301 cgatcagcgt acccttcatc gtaggattcg ggaatttctt ataataatat accagcacga
    45361 tagccgggat acacaataag ttcagcaaat ggacaccgat actcagaccc atcaaataag
    45421 cgatcagcac gatccaacga tcggcatgcg gacgatcggc ggcttcttcc catttcagga
    45481 tcaaccagaa taccaaggcg gtaaacaagg aagaataagc atatacctcg ccctccacgg
    45541 cgctaaacca gaaagtatcg ctaaacgtat aagccaaaga acctaccaaa ccgcaaccca
    45601 tgatcgtaat catctgtccc agagacatcg tcttatcgtc ttccacgata atcttacgag
    45661 ccaaatgagt aatactccag aaaaggaata agatcgtcag gccgctaaag agggcggaca
    45721 tcgtattgac cattaccgcc accttggaag ggtccgaggc gaactgcgta aataaattgg
    45781 ctgttaacat gaagaaagga gctccgggcg gatgccctac ttccaatttg tatgccgaag
    45841 agataaactc accacaatcc cagaaactgg cggtgggttc cattgtcatc agataaacgg
    45901 tagaagcgat caaaaaaacg acccacccca acacgttgtt gattagtttg tactttccca
    45961 tactttgtat aagtgtgata attaattgtt tctacttgca tacccacacg ggcagtcgac
    46021 cgcaaaggta atcatttacg tttaatacct aacgttccat tcccctataa attatataga
    46081 atagattaga attatattaa acaaacctta tcactcaagt gttaatagaa tagttgagta
    46141 ttaaaattat agggagatga aagaaaatta tgaactaatt gataatgaag aacgccacca
    46201 atatgaattt catatagaga gcgatacgtt cccagaatag agtatataaa aaataaggat
    46261 ggggtaattt atctcaccca cactgaggtt cccatggagc ttggaggtaa aggaattggt
    46321 agccaattgg tggagaaagt gctcttggat atcgagaaga aagacttacg tctcgttccg
    46381 ttatgtccgt tcgtagctgg atatatccag aagcatccgg attggaaacg catcgtaatg
    46441 agtggtatac atgtttaata tttataacaa aattatatgg gcaagaagat cgaatatacg
    46501 aatggtgaac tcaccattat ctggcaaccg gagttatgtc aacatgccgg tatctgtgta
    46561 aagactcttc ccggtgtcta taagccgaag gagagaccct ggatacagat agagaacgcg
    46621 acaaccgcgg aattaattgc ccaaatcaat caatgtccgt ctggcgcgtt gacataccga
    46681 atgaataaag aggtgaaatg aggccccccc gtctgtttca tcttgataga aaggagtatt
    46741 ccgtatcgga tactcctttt ttcaccataa ggggctcttt ctatgatttt ttgctagttt
    46801 tgtgatctag attcactatc aatgaaacaa atatgataaa aagacattct atcttaacgg
    46861 caatcctgct ttgtttcgtc gctttcacac aagtgatggc acaagagatg caggaacccg
    46921 aaccgcttcc gatcgatcct aaggttcgat acgggaaatt gagtaacgga ttgacctact
    46981 acatccgtca caacgatcag cccaaagacc gggcagactt ttacatcgcc caaaacgtag
    47041 gctccatctt agaggaagac aatcaacgag gtttggctca cttcttggaa catatggcat
    47101 tcgacggcag taggaacttc ccgaataacg ggatggacga atatatcgag agtgtaggta
    47161 tgcgcagcgg ggaaaacttc aacgcctata cctcctttga tgagaccgtc tacatgatta
    47221 ccaacgcccc tgtcaacaaa agcggcgtgg ttgattcttg cttattgatc cttcacgatt
    47281 ggtccgggtt cctagccttg accgactcgg ctatccagaa agaacgtggg gtcatccgtg
    47341 aggaatggcg tacccgacag gatgcccaga ctcgtctatg ggagcagcaa ctacccaaga
    47401 tgtacccggg aagccgttac gcaaaccgga tgccgatcgg ttcgatcgac gtgatcgaga
    47461 acttcaagcc ggacgagttg cgggcttact acaaaaaatg gtatcgtccg gacttgcaag
    47521 cgattatcgt cgtgggagac gtaaatgtag atcaagtgga ggcaacgatc aaaaagatgt
    47581 tcgccgatgt ccctgccccg gtcaacccgg caaaacggga acaagtatcg gttcccgaca
    47641 atgatctacc tctgatctcg atcgccaaag acaaggaggc atccaatacg atcctttata
    47701 tcttctataa acacgataaa ttacccaacg acttgaatcg tacgattgcc ggattggtaa
    47761 aggactatat ccagcaaata tgcgcgtcga tcatggacga gcgtttcgat gatatcttac
    47821 atcaagcgaa tcctccgttt atctatgccc aagcctacga cgatgataat ttcatgatcg
    47881 cgaagagcaa gggagcatgg accgtagccg ctcttgccaa ggaaggcgag atcgattcca
    47941 cactgaccac gcttgtcaaa gagacccaac gggtaaaaca atatggcttt acgccatccg
    48001 agtatgaacg ggcacgcatc aacgtgttga aacaatacga gtccgcttac aacgagcgga
    48061 ataaccaaaa aaacgacgct tatgttcgtg aatatgtgaa tcatttcacc aacggcggtt
    48121 atatcccggg cattgagatg gaatacacgc tattgaacca gatcgcccag aatatcccgg
    48181 tagagcaagt caaccaatat atccaagata tgatcggaga ggataatatc gtgatcgggt
    48241 taaccggacc ggataaagaa ggtataaaat atccgaccga ggagaacctg ctccgtacat
    48301 tcctcaaagc acgacagatg ccggtagagc cttataagga aactgtctcc aacgagcctt
    48361 tagtcccgac cttgccgacc ccgggccaga tcacggagac aaagaccggc cagcccttcg
    48421 gagcgacggt atttacctta agcaatggta tcaaggtggt attaaagcct accgaattca
    48481 agaaggacga gatcatcatg accgctacca gcccgggagg aagcacttta ttcggcacga
    48541 aggatattga taacttaaaa gttttcaatg acgtgatcga gataggtgga ttgggcaatt
    48601 tctccgccac ggatctaagt aagcgtctgg ccggaaagaa ggtatcttgc gccctatcgc
    48661 tcagtcaaga tagtgagaac gtgaacggaa tggccgctcc ttccgatttg cgaaccttat
    48721 tcgagttaat ttaccttagc ttcacggctc cccgcatgga cgaggaggcc tacgcatctt
    48781 tcgagacacg gacaaaagcg caattgcaga atatggagtt aaatccgatg gtcgctttca
    48841 gcgactcttt gtctaaagcg gtttacggag ataatcctcg tgcgtcacgt cttcgtccac
    48901 aagatttcga acatatcagt tatcctcgta tcatggagat gcgcaaggaa cgcttctcgg
    48961 atgcttccgg tttcgtattc acgtttgtag gtaatatcca gattgatagt atccgtccgt
    49021 atatagagca gtatttagcg acattgccat cccaaggaaa aattgagaag ggaaatccgg
    49081 cggaggttcc atcgatgcgt aagggagact atatgaatcg attcaaccgc tccatggaaa
    49141 tcccgaaagt aacggtagcc aacctctata ccggacagat ggagtacaat ctggagaata
    49201 tcatcaccgc taccgcattg aaacaagtta tggacttggt atattacgag aaggtacgcg
    49261 agaaagaagg aggaacgtat ggcgtcggtg tatccgctag aatctcacct ttcccggaag
    49321 gaagaacgac attacagata ttcttcgata cggacccggc caagtgggag cagatgaaca
    49381 cgattgtccg caatgagttg aaacggcttt ccgaggtagg ccctcgtcaa gaagatttca
    49441 agaaaacaca ggataacctg ctgaaacgtc atgcggaagt cttgcaggag aacagctatt
    49501 ggttgaacgt attggatgat tattattata aaggatttga taccgatacg gattatgagt
    49561 cgattgttaa ggcgctgact cccgagaaga taaaggcatt cgcccaaaag cttttgggac
    49621 agggtaaccg ggtagaagtt atcatgcaac cctagttact attttgagag gatgagacgg
    49681 ggcgtgcccc gtctctactt tgatttcttt agtttaaaat gatcgaatcc ttccccataa
    49741 accccgatta cggcgctttg ggatacaaag gcggtcggat caatatcatt aatgatacgg
    49801 aaaatcgtag tggattgccg ttttttagcg agcacgaaca tcatcttctg ttcttgcccc
    49861 gtatataacc cggtagcatc gatcaccgta acccctcggt gcaacgcatt aatctcctta
    49921 ccaatctctt gatacttctt cgagatgata aagaattgca cggactggcg agcactgttc
    49981 acgatctgat ccagcacgaa actacaaaca tataacgtta caaaaccata taccactttc
    50041 tcccaatcct ttagcacgaa ataactggag gtgataataa tcatatcgca gatcatcatg
    50101 acccgcccca gcgttatatc ccggtattta ttgatgatag cggcaataat atccgttcca
    50161 cccgtactac cgttcgagga gaaagcgata ccgataccac ttccgcagaa ggaggctccc
    50221 agcacacatg ccataaacgg ttgatcttgt aataaatgca tcccggctgt cagctcctgg
    50281 ataagggaca agaaaaaagt aagcgtaaac acggcgaaga tcgtcttgat actgaactta
    50341 aaacctaata ttttcaaggc aagcatcagc aagacggcat taatgaggaa gtaagtgtac
    50401 tgaacgggaa atcccgtagc ccagaaaaca atggaagcga tacccggcac tccacctgtc
    50461 gtaatgtcat tcggcaaaag gaaaacggtc catccgatac cgtaaaggat catcccaaga
    50521 gcgatcatta aatagtcccg tgtctcccga agcaggactt gtctggataa ggaagaaatt
    50581 gataaagtag atttcatctc atttgtttat ttttagcggg cgcaaaggta atgaaagtta
    50641 ttgataggaa atgcttcacc ttatatttag ccggaaatat aatggttcac tttcccctat
    50701 ttacagagac gtaagcaaaa gccaaggaat gttaactatt tatcagtaat aacccctttt
    50761 atataacatc acctttattt agaaaagctc tataaacgag aacatgaagg agaaagcagg
    50821 catttatacg ccttttccac acaaaaagac ccgtttttcg ataagaatac cctcgttaga
    50881 ttacacatat agtcccgttc acccacgcct gtacaggcgt aaacccacac atatagtcac
    50941 gataggctac acatatggtc ataatgggcg atatgactac cttataatgg gcattgttgc
    51001 cccctaacga ctgggccata aggcataaga tatgagatag gatgaattaa tttcgctaga
    51061 ataaaaggcc gtttttcaac aagtcactag cggatagacg attgctgttt ttttctttcg
    51121 tttttaggag acgagacgta ctttggcccg aaataatcga ttctcaagga cttcagttta
    51181 caaattgtca cattgatatt ctaaccggaa cacgcataag ccctttcacc caattgtaga
    51241 gacggggcgt gccccgtctc tacaaccaag tatgtatgag ctgcaaatat agacttacaa
    51301 tctcacattc tccatttcct cacacttctc ttcccgcaag cgttgaatat ccttgatctg
    51361 gcgatcgaaa aacgtgagca agtcattgat gagccgtccg ttctgggata aaagcaaaac
    51421 cccatccatc aattgcgttg acaggtagcg aactttcata ttacttacat gctgatcggg
    51481 acgctgcaga taaacggcca tacatctgta caaaattggt gctatttgta tccacggcag
    51541 ttttagacct accaatagat ttttcacgct ttgcaactga tggttcagat aatcgaaatc
    51601 atccgcatct ctctcaaaac agaaagcttc tttcaagcgc cgtgcctctt ccttaaaaaa
    51661 tacatcactc aacatttcca tgttcgaaac cggagcgtct tgctctgaac cgacaggttc
    51721 agttacggga taaatgtttt ccgcttccat aatatattag cattaagcag gcggaaaaaa
    51781 gaacggtccc gcctgacccg ttgctaaaca ctttaccaga aagctggagg cacattaatg
    51841 cactccacgg gggtacggaa ccgtcatatc ggatcggtta caggcaaaaa aatgcctgca
    51901 accgaataga agcaggtatt ctactctgct ttctggtttt aaaatgttta gcattgcaaa
    51961 tatacttctt tttccggata tccaacctat agaggataaa taatcaaggc aaccgtacca
    52021 attatctatt tatctatcgg aaagatttaa atatatgttg agactataaa tagagccccc
    52081 tcacgctata ctatcatgga aattgcggag gaggccgttt cagtctaaag aatcttataa
    52141 cttgacagaa atttgtt
//
LOCUS       DBMDTB010000015        49374 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_285_length_49374_cov_11.420372, whole genome shotgun sequence.
ACCESSION   DBMDTB010000015 DBMDTB010000000
VERSION     DBMDTB010000015.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 49374)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 49374)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49374
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_285_length_49374_cov_11.420372"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(112..1368)
                     /locus_tag="ACZPB4_04290"
     CDS             complement(112..1368)
                     /locus_tag="ACZPB4_04290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HIR1097473.1"
                     /translation="MKTNRRDFLKTLGGIAAFTIVPRHVLGNGFIAPSDQLTKGIIGT
                     GGMGRGHVDYAGTRLVAVCDVDKNHLELGKQLVKDKIAAYHDFRDLILDPNVDIVHIA
                     TPPHWHGIMSVEAAKAGKDIWCEKPMTRTIGEGKRVMEAMKQYGRMFRLNTWFRFADP
                     FYGLGTPVKPLKKLVQSGMLGWPLKVTISKHTGFDWKFYWVGKEYLEPQSVPSELDYD
                     FWLGPAPYKPYNPHRVHQTFRGYWDYDGGGLGDMGQHYIDPVQYFLGKDNTSPVKVEV
                     DAPQQHPDAVGTWRSITYTYEDGCQIVLWGGDYGDPNTPYISGPNGNVYKNFVCDIPD
                     WEKKLSGYPEPEPQVTDFIECVKTRQPFALNERNGFRSATIVNMGAVALRLNRTLHFD
                     PVKLEFINDEAANRLLDQPMRAPWNI"
     gene            complement(1514..2914)
                     /locus_tag="ACZPB4_04295"
     CDS             complement(1514..2914)
                     /locus_tag="ACZPB4_04295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family protein"
                     /protein_id="HIR1097474.1"
                     /translation="MENTRRSFLKKVSAAGIGAAGLAMAGNAGATTTAAEPQKKKTAG
                     KDDGKLRFGFIGTGSRCHEHINNVLAIPGNKIVAICDIQQGPIDSTLKHIAKFNVPAP
                     KVYKGGEREFENMLNNEEFDCVIIASPWEWHVPMSVAAMKAGVPYVGVEVSAANTLEE
                     CWDLVNVSEATGSHLNIMENVCYRRDCMAALNMVRQGLFGEILHGGCGYEHDLREVKF
                     NDGTHYNYVPGSGDLRMGPTAFAEAQWRTNHSVHRNGDIYPTHGIGPIAHCMDINRGN
                     RFLSLSAMATQSRGLHKFIVDNGGENHPLAKVNFNLGDIVTSMIKCSNGQTIIVTHDT
                     NSPRPYSLGFRVQGTEGLWMNDGDHVYVQGKSKPHRWDDSDEWFKKYDHKLWASLESQ
                     AAEAGHGGMDYIMMYDLIDAIRNKKPAPMDCYDAAAWSAISGLSEMSIARGGALVDFP
                     DFTRGQWIHRQPQFAL"
     gene            complement(3015..4541)
                     /locus_tag="ACZPB4_04300"
     CDS             complement(3015..4541)
                     /locus_tag="ACZPB4_04300"
                     /EC_number="3.1.6.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase family protein"
                     /protein_id="HIR1097475.1"
                     /translation="MNKYCIMSVLAGFSLPTTLIAQSAPRQPNVVIIVADDLGYGDLS
                     CYGAHRIQTPGMDRIANEGIRFTQGYCTAATSTPSRYSLLTGLYPWTNRDAKILPGNA
                     ALIINTQQVTLPKVMKQAGYVTGSVGKWHLGLGDGVVDWNKLVYPGAKEIGYDYSFIQ
                     AATNDRVPCIFIENGRGVNLDPNDPLYVSYKENFPGEPTGKDNPELLRMLPSVGHAGA
                     IVNGVPRIGFQKGGKTAQWKDEDMAELFLEKAKGFMKENKDKPFFLYYGLHQPHVPRV
                     PNERFAGKSGMGPRGDVILEADWCVTEFLKEMDKLGLTENTLVVFTSDNGPVLDDGYQ
                     DQAVELVGDHKMAGPLRGGKTSLYDGGTCIPFMLRWPAEVKPGAVSDALVCQMDLLAS
                     LSALIGQTYSDKVDSQNTLPVFLGKGGNGRKELVLEGYFNYALRDGDWVMIPPYPDTY
                     GDAEEAAFAGNSNCYQLYNVKEDIGQQVNLAEKEPKRLRQMMMTFERLKRETGKITNF
                     "
     gene            complement(4548..6239)
                     /locus_tag="ACZPB4_04305"
     CDS             complement(4548..6239)
                     /locus_tag="ACZPB4_04305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RagB/SusD family nutrient uptake outer membrane
                     protein"
                     /protein_id="HIR1097476.1"
                     /translation="MKKIAIVALAAAATFITSCDIERMPYDKYTEDKIMEDKDAAVDV
                     LLNGCYAKLKTASEHLHYCGEFPGDNVCKDKPTTNPFGTYFTYQHTVNNGGLSTVWNS
                     AYNIISQTSSLMKMINENESPELNQKLGEAYYMRGMMYFYLCRVFGRPYYQEPEKNLG
                     VPIVNGMPEDMDNLDLPDRSSVKDTYEQVLSDLKKAEELMSDFKSPAYASKYAAQALL
                     AKVYMYMSGTFENPNKEYAQLSYNYANEVIESNQFSLLSRSTFMTYNELAPDAASQTE
                     TIFAVKFIASDWDDWGSPLGSMYAEIDGQGWGEVYASAKYMDLLHETGKNTDAREAFI
                     HPQYKKNDAGDQIPAFRFVANLYTDGKISGYVYRQGETKEVGGKLIATVDDEEYTLTP
                     VDVDNKRYSISYKGKTYVGDYDYLMLESQGNPKFYSYKCSKQEGYPHLYSPVISRLGE
                     LYLIRAEASAKLGNYTKALADLNTVRTRSLPNAGYKSLDATNAHELIMKERQLELAYE
                     ADRGFDVYRVGDTMKRHYPGFHDGVPEYPATSPLAIQYIPQSEINAYPGTLTQNP"
     gene            complement(6254..9556)
                     /locus_tag="ACZPB4_04310"
     CDS             complement(6254..9556)
                     /locus_tag="ACZPB4_04310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SusC/RagA family TonB-linked outer membrane
                     protein"
                     /protein_id="HIR1097477.1"
                     /translation="MEMNYFKKTGKMMVAACMLAGLPFIPGTVSASELQTQMMSVQME
                     STTLKELFDLIEEKFNYTFLIRNNDINLNERISIDMSNRSVEEILTTALKNQHADFVV
                     NNNRIVVYKSSSNPNELRNTERMVAQQTITISGTIVDAVTGEPVIGANVLVKGTTNGT
                     STDFDGKFSLEAPAGATLVVSYIGYVNHEVKATSAPMTIRIKEDTQNLEEVVVVGYGV
                     QKKESLTGAMQVVSNEKLLDATSPTVENLLSGKAPGVQVTSGGGQPGAAGKVVIRGKS
                     TVNGSTDPLWIVDGVIVGTDAGSLNPADIESMSILKDAASTAIYGSQGANGVIVVTTK
                     KGKIGKATINASVKMGVNQLHRGNMNMMNGEELYDYYKSFANQDALPSYFTEDLRNRN
                     FDWWKEGTHLGFAQDYNVSVSGGSEKIKTYTSVGYYNEDGAVKGYDYKRYNLRFNVDY
                     QATDWLTIKPKVWATRSDVMDQQQDLGAIMYVNFPWDSPYDENGDLIQQYRPTDWVNS
                     DATNYLYDLQWNYEKKTSYEFMGNFDFDIKFTDWLTFASVNSYKYNNILFKGYNDPRS
                     KAGEADNGLLQDKTTTSYRVYSNQLLRFNKVFDKHSINAILAYEWNSYTREIKDQTAA
                     SFAPGFSVADVATTPKTIKGSQEEWAVQSYLFNANYAYDNRYLLSFSFRRDGASNFGE
                     DAKYGNFFSVSGGWNIHQEEFFKAKDWVQQLKLRASYGSVGNRPTELYSQYTLYAMST
                     GYNGDPGAVIAQKENKNLTWEKTYTAGVGIDAILFDRLTINLDYYNKKTTDLLYKVPL
                     PGVTGITGIYRNVGSVKNNGFEVSLGVDILKGGDWNWSVAANLGLNRNKITELYGGKS
                     EIITANAGTSYYIYMDKILTPGQDVDTWYGTEWAGVDPQTGAPLWYTTNEKGERITTS
                     DYSEASKHQTILGKLSPDFYGGFSTNLSWKNIDLSAVFGYSVGGEIYNYDRSMYDSDG
                     AYVNYNQMNLRDDWNRWEKPGDIATHPKAEYGNKSQSSKGSSRYLEDASYLRLRSLTL
                     GYTLPWKIQYVDNVRLSFSGENLFVLSGFSGVDPELPAEVGSQYKAGSVGVAISPYPQ
                     ARKFMFGLNVTF"
     gene            complement(9640..10662)
                     /locus_tag="ACZPB4_04315"
     CDS             complement(9640..10662)
                     /locus_tag="ACZPB4_04315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecR family protein"
                     /protein_id="HIR1097478.1"
                     /translation="MEIENKHIEDLIYSYLMGDISEEGRNELLQWLETDDAHKQCLSE
                     MADCWATAHVPLFASDMKADFQKHFGALIDPAIPSEKNHWLNFRFLGKVAASVLIVVS
                     VGTASYYIGTRHNQPKSAALAYFETTTPMGAQTKVVLPDQSVVWVNAGSTLRYGSDFN
                     TNGRSVQLDGEAYFEITRDSLKPFIVKSKKLDIKVLGTRFNVKAYGMDEMTDVTLVSG
                     KVNVSLRDEVAHAGDVTLTPNRKLSFNKQTNKVRVSEVDAKDALSWMDGSLKFSEQPF
                     MSIAKDLERKFNVRIRVESDLLRKEIFSGSFTKDYSLDKILREVDVDHKYVWTRSGDE
                     IIIKDK"
     gene            complement(10744..11346)
                     /locus_tag="ACZPB4_04320"
     CDS             complement(10744..11346)
                     /locus_tag="ACZPB4_04320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma-70 factor"
                     /protein_id="HIR1097479.1"
                     /translation="MTFVLIVKEDIISRINNGDAKAFEQLYTTFYVYLCAVATKYVYN
                     SEAAREIVNDVFMNVWNHHSALIHPVNAYLIRSVRNYCLNYLRDKRQQEVPLSDVQES
                     LLSIQELQIDADPHPLAYLENKEFEEKIYRAVDSLPAKCRDIFVQYLYHNKTYEEIAI
                     TNHISSSTVRVQIKIGLAKLRELLGDLYPLFLLIFNFFEK"
     assembly_gap    11653..11752
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(11832..13097)
                     /locus_tag="ACZPB4_04325"
     CDS             complement(11832..13097)
                     /locus_tag="ACZPB4_04325"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HIR1097480.1"
                     /translation="MTFEDLDLIEPIRKALVQEGYTTPTPIQSEAIPIVSQGYDLLGC
                     AQTGTGKTAAFSIPIIQRLYLQKKKGYKRGIKALILTPTRELAIQIGESFAAYGRFAG
                     LRHTVIFGGVGQKPQTEALERGIDILIATPGRLLDLIGQGFIHLDTLEYFVLDEADRM
                     LDMGFIHDIKRILPLLPKKRQSLFFSATMPPEIERLAGTILSEPQKVEVTPASSTVDA
                     IDQSVYFVEKAEKINLLKSLLENPELESVLIFTRTKHGADKVARVLSKAEIGAEAIHG
                     NKSQTARQRALTNFKDHTTRVLIATDIAARGIDVDHLTHVINYELPNVPETYVHRIGR
                     TGRAGREGVAFSFCDAEEVPLLKDIQKLIGKEVPIAGGHMYETKEVKAAVAEKKEAIK
                     QESKRRNMFGSKRDGSYWRNKKRAANSSK"
     gene            13206..15041
                     /gene="recQ"
                     /locus_tag="ACZPB4_04330"
     CDS             13206..15041
                     /gene="recQ"
                     /locus_tag="ACZPB4_04330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HIR1097481.1"
                     /translation="MKELLLLLKKFFGYTSFRPLQADIIQRILQKEDSLVLMPTGGGK
                     SICFQLPAIYLPGTALVVSPLIALMKDQVEGLIANGIPAAALNSMMPEEEQQQVKQLC
                     VQGKIKLLYISPERIKMEADWFLPRLDISLIAIDEAHCVSHWGHDFRPEYTQLAILKE
                     RFPKVPVVALTATADKITRKDILEQLRLREPQTFISSFDRPNISLTVRRGLNKKEKIA
                     AIVHFIRGHREQSGIIYCMRRNDTTELADELAMYNIKAIAYHAGLLPAQREQAQNDFI
                     NDRVDVVCATVAFGMGIDKSNVRWVVHYSMPGSIENYYQEIGRAGRDGMKSDALLFYS
                     LSDLIVLRRFAEESGQSEVNLEKLNRMRRYCESDMCRRRVLLSYFGEEADHDCGNCDV
                     CKNPPQRFDGSVLIQKALSAVIRTGEHVGMQMLIDILRASARAELLERGYDKLKTYGA
                     GRDLSYKEWKEYIYQMIQLGYMEIDYAAERVLRMTPLGRRVLYGEQKAQLVIYREPDE
                     LTRPVRRGERKSSFKAQPIRPIRSASTDETLLDSLRQLRKQIAEREHTPAYIIFSDDS
                     LEDMVEKKPVTLDQFSDIRGVGQIKLDRYGKVFVALIRFVLKLPK"
     gene            15136..16314
                     /locus_tag="ACZPB4_04335"
     CDS             15136..16314
                     /locus_tag="ACZPB4_04335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4876 domain-containing protein"
                     /protein_id="HIR1097482.1"
                     /translation="MIDKHFSLLTHLLCLCFLAGCENEYFKTGSIHIQLKKPSGYVDI
                     SLANIPVTLINQSIGCVYTTTTDTNGLALFELTAGICAISANQETTTGNRDYILSGSL
                     SNIQFEANGEERSVEIPLEVSERGRLLISEIYFSGCLWPDGKNVYNKDQYLTLVNNSD
                     DLIFLDGLCIAQAGPVSVTKPSGWMLHTDMKEIPLFMMCWEFPGTGTEYPIQPGERQT
                     IAINAINHTNSEVGVPASLDLSSVEWAFWDPILTGSQISAGVKPLNLVWRGTGFSYLF
                     SMNGPTILLFRPKTDLREWIANPDHIQKEPESFNTLKYLHIPADWVQDIANFVSSTST
                     VAYTRIPSSMDVSPGIATSGGSGLAMRRKYEQEGKRFRWKDSNNTAEDFEKSPPSLKR
                     "
     gene            16321..17838
                     /locus_tag="ACZPB4_04340"
     CDS             16321..17838
                     /locus_tag="ACZPB4_04340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6850 family outer membrane beta-barrel
                     protein"
                     /protein_id="HIR1097483.1"
                     /translation="MKITIILYMISLSVYASRSWAQQESAWALSANPVSISYVPKDSA
                     MEAGLSYLIHQAALPASDQPDQTQTYRAYVSGNRKLGLLWLAGGIDWSQSLLEGRKWN
                     LLSQPDYLITAGDSLGEPQRIEKYRIYGQAAYVLSPKIKVGIDGDYTATSNEDRSSYH
                     IYHGMAHLIQISGGIVYEQVRRRFGASIHYTHRTEELTYDTDSKDKLYTFPLGYWLPM
                     QELSGSFLFRSQGKRLGVSLQTETLKEHWSLFHDLSYETQQLADNPNNSGNLRGWEER
                     LHQICYQGRFTRTNKSWTHIWSPTARFNQTTANRILQRNPTTSSSAIWTTFATYRLAR
                     QRMLSTQLSYEATKNDTSGGKASTWQMTVGWNRLENDFYIYPFTVKQYTGLFHGEIAF
                     FRQIRLPKENKLSIRPSVYIVSGYGTEIKWEKETQKDENGSAEIKLEQNMQKVNEDFI
                     ARTATRLGIGTEMEYRHPIHSALSAGFRLKGSLEQTTSPQSTLGGGGNFSIVIWL"
     gene            17853..20342
                     /locus_tag="ACZPB4_04345"
     CDS             17853..20342
                     /locus_tag="ACZPB4_04345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor domain-containing
                     protein"
                     /protein_id="HIR1097484.1"
                     /translation="MRYSTLYKIPIRIVTIFLLLSSLHPGNYLHGQEQPDTLSFYLPN
                     ILVTAIESKTPGTVSLLPASTLEHTQPITIADLTQLLPGGLTNNSGVTDAQYFSVREV
                     SLKNGVNQFHKNAAMGAQIWVDGSPLHFNTGINEPYEGYDARFLSLNQVKEAEIIRGI
                     PSARYGNLTNSVLLLKTHQGRMPLSTSIRYNPKLKQYMLGKGFCISPQGHTLNLLADY
                     TSQGDFHTGGIRLANLYHWLPAGKKLELSLTYTSRIGKEKQFVNEQNHTQRQRLDQRF
                     SIQGEWQPDRRWLKKLSLRIDGSLQKSKQTKSQVNNASSQLYTDQKESGEWEAHVLSS
                     NYMYTLVNESRPFYVETEMLASTSFPLRQRREISLAAGFSWRGEGNEGRGRDFDRQRP
                     PSTSIRPRSFREIPSLHTFGGFIEATYRTPNLHVEAGLRNQGLKSRDYALIYQTEPRL
                     NLLWSLCSSPSGYTLSLKAGVGWISFMPTLEKLYPEAIYNDKVSFYYNDSNESGNTLG
                     ILTTHAPGMERNMKLKPTVNRKIEVGLIGKTPAIRLDMTVFFEKQTDGFSSSAQYIPF
                     SYREYDYLSTAQLRPEYKDGQVWVNGKAVPYQEKYSYTPVSVPVNTLHRKKHGIEMVA
                     DLGTFSPLRTSLIVDGIWLYVREKNTALNGIWPIQYTDKTEYPYVGFYDRQGGPGNES
                     RSEIISTNFRFITRIPRIGLVTTLTWQMIWLYKYRTLYNGSTGENVWPLYWCGTDGII
                     HPFTEAQKEDPAFAPLLSTTAPERFLPNSYKPYGMLNIRVNKAFGEHITLAFFANNLA
                     DLRPTRYSASTRSYLQQNTQPFFGLELQIKL"
     gene            20347..21951
                     /locus_tag="ACZPB4_04350"
     CDS             20347..21951
                     /locus_tag="ACZPB4_04350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIR1097485.1"
                     /translation="MKTSILYIFLLSVLYACDSHSLLPPKQQLDQQIAQLNDYSLLSG
                     RLNDQLCEEIETHAQEIGNDSLLLATRQIIYTRYCRLQDTAHARMLLDRMKPYAIRIK
                     DKHLLMNHLRMAFLHAQTRQPAECERWINEARKYAYINPQNWYITAANACLECGLYPQ
                     ALIYADSALVNLKYKVISSPHLVKAIALSRTGKTAEAEEWTKRCITDIRHFQAKHQIH
                     TISYLQYQLFMEYAVSLRKHGKNKEALSVLEELDRVSFNNVATPLLRNKDNIEEYKVR
                     VARMLSECYYTTGNQSEAIQQANRADSLQSHYAQEQMNIRRKMISESLQNELLSTRLK
                     SQKVEAEQARLIQYILTGIIILLMAILTGGYLWWRNHRRSLRQLFDLLISHHAAWLLI
                     HDPLPLISRPQIKLPDHSEANTEVATKADNLLYQRILSVMKEQKPFLNPNLDLVTLSR
                     LVGTNRTQLSTTLNRQTGMNFSRWLAEYRVHHLLSLVTLHPDSDITALASESGFTSRT
                     SFFRQFRQVTGLTPNQYRNVRKETDK"
     gene            22132..22521
                     /locus_tag="ACZPB4_04355"
     CDS             22132..22521
                     /locus_tag="ACZPB4_04355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIR1097486.1"
                     /translation="MEEKQKPSLIERRLYARILQIMEDKKPYLDPQFNLCQLANLACT
                     NRTRLSSTLNNQTGMNFSRWLANYRVKHLIREFSKCLTQEPKELYKKAGFTSRTSFYR
                     QFKEVTGNTPIEYFANLYYDNVNHSTK"
     gene            22530..23384
                     /locus_tag="ACZPB4_04360"
     CDS             22530..23384
                     /locus_tag="ACZPB4_04360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097487.1"
                     /translation="MRHLTLLLLSVFTVHQAKADILIPLDKYPTGEKRFNLQINGSHD
                     TSTPWLSTTSFGVDEDGQMGNPENWTSEQIDEDNQSVSHRLIMNSISLRLSYRIWDNL
                     SLWAGIGTTNFTHEETFRDDDDLSSTIFSKNMVPIYSGGLGYGHAFTDRFFMSTQPGV
                     RYANSDNMTTEVYYQGKTIPLRDLSLNRRYLEWAVPVVAGYALGNFVPYAGILYKDYT
                     MKDRYEFTKTYAGEDYTVRIDETFHARHKLYALAGVNYFLADNISLGVNGSFGNRQSV
                     QLQFNISF"
     gene            23406..25922
                     /locus_tag="ACZPB4_04365"
     CDS             23406..25922
                     /locus_tag="ACZPB4_04365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097488.1"
                     /translation="MRTTLKAQAIRLIAIFLLICASTTIVKAQISQHPELYKVKEFHN
                     MDKDGGAYYCFTDAQYYQGKLYGVYIDNNGPSSIRLIAFEVNGETRTMEQSTVGDTGK
                     KMIFLNDFGVYQDAEIIVYRNRFYVLWKNNTNGQIWIGEVDMKKGEYKKTRMLDDGKT
                     YANFAATIYRDKICVILHRRTNKKLQVYQYGDPELNSGWDWCGTVRNAGHDNIELKGS
                     TGISMEYDPDDHWDATSWYGYDDTEKKNVEKLIVGRLKSGTFEAFSYSGEYGKDNTWP
                     SNWEEYAHHDIGRSKTFSLKLIQADIEGYAADNTDGYKASSNPLIFSYCSYDGKGTGE
                     HFLKKFYPGSNSFAADAPIYTDLPYGYTAVATAADPTTETAPGGGLYYKQYIYLLRGN
                     QQPYHWFKHSYVASIRSNEIVERRSSFNDEKALFGNSELRNLVRLVGIIEGPPPTVVD
                     NNEWFGDLGVASSLAFTMGSGTSNSVSRLYKSDLKCSFGPHTDKLTAAFGGGYSFQKQ
                     HEEVTSQSESITVTFEANDTADYRAIALYSVPILTRCDLEYLSPTRRQSVRMPIFSYT
                     YMTRQSIKQVEVPLDLEPFRIDNPSKLGDWEAREILTMTASEPNVSKSVNFSLNSERI
                     DMTLETSGTISDSQTKGAISLMDLKFPFFQLENQSSWEWTDQTTATTSQGISASYSKI
                     RRTDKHVRPEETAESFSSTLYLLTAEKSNTLRDQYYPKLLERKISFGTDTFPFMVNSD
                     KPFVLAWDINNITYVRGDVSATGNEEVTTDEPLSIRFLDGMLTVDCLPGATVNVYSMN
                     GTLTGHQQAVSGKAIFSLPGHLYTVEVVTERYRKVQKVVR"
     gene            25937..27430
                     /gene="preA"
                     /locus_tag="ACZPB4_04370"
     CDS             25937..27430
                     /gene="preA"
                     /locus_tag="ACZPB4_04370"
                     /EC_number="1.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017113 - dihydropyrimidine dehydrogenase
                     (NADP+) activity [Evidence IEA];
                     GO_process: GO:0006210 - thymine catabolic process
                     [Evidence IEA];
                     GO_process: GO:0006212 - uracil catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent dihydropyrimidine dehydrogenase
                     subunit PreA"
                     /protein_id="HIR1097489.1"
                     /translation="MKTNLLQRKRLLTEESNRCYLCDDPVCTKACKPGLDPGRLLRAC
                     KMDNLAGAILRAYRMEACKDCDGHPCEKACLRGRTDRAISITQIVRQLQDMPNPTDSS
                     PLTSSPDLAIDFCGVRCANPFILASSPVAHNYEMCVRALEAGWAGICFKTISFYPSHE
                     VSPRFDQMEVDGVPFIGFKNMEQLSEASVEENFDTLYRLKQRYPDKLIISSIMGRTDD
                     EWTRLAQYSMQAGADIIECNFSCPQMTQEGMGSDVGQSPELVRRFTAATRRGTHLPIL
                     AKMTPNIGQMTPVALAAHEGGATGIAAINTIKCITRIDEKAFTARPVVSGLSSVSGYS
                     GRAVRPIALRFIHELASDPSAGKMPISGIGGIETWRDALDFLLLGCTNLQICTAVMQY
                     GFRIIDDLCEGLRLFMQENGYKDLSDLIGIALPNIVPPERLERTQIHRPTVDNSLCLG
                     CGRCFVSCNDGGHQAIHFTSMRKPVIDEQKCVGCHLCALVCPTFAIH"
     gene            27435..29570
                     /locus_tag="ACZPB4_04375"
     CDS             27435..29570
                     /locus_tag="ACZPB4_04375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5686 family protein"
                     /protein_id="HIR1097490.1"
                     /translation="MRIETEHLILLFILLLCPLVHPDLRAQEKTPVTRADSIMRQVIH
                     QAPIYEHVLESYEAETYVKGRTHVPRKNKLLRYAYLVFPIERHPRNAFFEMSGLTRYD
                     APNHYRNKIVAINSSHLAAGRHYKEIASFVNLNVYSPTIYNKGMIMPLSPDAFKYYTF
                     RQEGTDTISGTLVYNIRFTPRQWSQKLLSGNLYVTDELWTIDRIEIQGHSSFSEFNLS
                     IRFNRDEKHFILPEEADLQVCYHALGNRIESDIHAAFRYKSISWVEEDHESRKLYSLD
                     QTQYYTITSDTLSFTQDSTYWNSRRDKPLTTDEKALYTTGTNVVRTEADSSALTRYLQ
                     LGERLTSTVNRDYKSTRVKYSGLLNPFQLSFGSNGITYKQEARISKTFEHDRQLRFHP
                     EIGFLFKEKELRLRLTTDWEYHPERQGILNLTIANDNQSYSSEVIHQINEILKDTPIR
                     FEDLNLKYFQHYYAKLMNQIELMNGFRLSAGLAYHYRTPVKKNKDTGLDLKDHNEFTP
                     VIGLTYTPRQYYWMDGYRKEYLHSHYPTFRIELARSIPDLLGCTGNYWRMEAGMNQTV
                     RLGLSERLSYNLSGGLFFNQHNMYFADFSYFAKRYFPEPWGDRFGGIFHNLGGDWCNA
                     SDKYIQGHLMYESPFILLRFLKPNPKAHKYLVSERFYLSQLWTPVLPNYSELGYGIGS
                     DLFHIALFLGFEKFKYQSVGLKFALELFR"
     gene            29589..31430
                     /locus_tag="ACZPB4_04380"
     CDS             29589..31430
                     /locus_tag="ACZPB4_04380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097491.1"
                     /translation="MNKRNTIKQLLHRGCLLMGISAITSSAFAWDFAEHRKIGDRAMS
                     LLPRYLVENGIFPNEAVADSALLQILNMSHMPGSNAYAMNELTQLPNIVTYGTLCGLA
                     GDHVENPMLLETGLQTHFSKTNRTLALETQAMNEFLTGANSKELLDINLAYGILAIKD
                     LSHFYAYGKGLNEHLKMIDPELIRRLQRPSEVNKVFDKLNQLPSMSKYFCIHIFAIYL
                     AQEAGKEMCKGDTQMASNLMFYATMYEAFAEHFLQDSFASGHQMVRRGFSASAVSNNK
                     SLHDFYNTIPVQTANLKGETWSAYGDKRLNQNRMEYNEADDYRHIRVTEKHPYSLEKG
                     DSYERETKVFYQVVTATCESIVEVWKAYQNALEGSGENILNEIPSERDDLPQFVYDRF
                     PVIKDFPIPFGTDLDDVPLKASVADRKDELQLIVQEPFTRNFIRSRVANSFMFLIGTP
                     IHSNRDGVMTYGGRLNVSMINWHKFGKGKGMIMEPGDIAHWVSPTISGYYMHAPSSSY
                     TIKNWNVKAGANYNMDIFVSPKRFLGLYSYFEMGIDRRNDETRFLVAPSVGIQLGSLI
                     GVHNFNMPGWLRIPLGIILPLKFAVTCNKVAGRPVEWISNMEVDILF"
     gene            complement(31532..32146)
                     /locus_tag="ACZPB4_04385"
     CDS             complement(31532..32146)
                     /locus_tag="ACZPB4_04385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class IV family protein"
                     /protein_id="HIR1097492.1"
                     /translation="MCPSIETLSGSPFVETIRIERGRIHNLPYHNARMNRTRRELFGA
                     REEIDLAGYIHPGPHQERTKCRVEYTCEVLQVEYVPYRMRPVHSLRLVTCDEIDYSYK
                     STDRQCLNDLFAQRGGHDDILIIRDGLLTDTSICNVALWNGTSWITPARPLLCGTMRA
                     YLLDKGLVQAGDIPVEDLPKYTRIRLFNALIGFGEIDEITRIYV"
     gene            complement(32130..33137)
                     /locus_tag="ACZPB4_04390"
     CDS             complement(32130..33137)
                     /locus_tag="ACZPB4_04390"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HIR1097493.1"
                     /translation="MTEYTQEEAVFRMNEMGKAGRPFLFIIDYKRERIYVESPEEIAP
                     SELLYDLNGFTNTNHECNLRDSSHLISGEPVEWQPSYVSFEEYAHSFETVARHIHAGN
                     SYLVNLTCATPVHANLSLKDIFYQSKAMYKLWMRDRFVVFSPEIFVRTRDGLIYSYPM
                     KGTIDATLPDARRRILDDPKEAAEHATIVDLIRNDLSIVASEVCVPRYRYIDELRTHN
                     GSLLQVSSEIRGRLPEEWNAHVGEILFSLLPAGSITGAPKKKTLEIIAEAETYERGFY
                     TGVMGYFDGQDLDSAVMIRFMEQVSPRSFIFKSGGGITSKSDVRSEYNEMKQKVYVPI
                     Y"
     gene            complement(33137..34012)
                     /locus_tag="ACZPB4_04395"
     CDS             complement(33137..34012)
                     /locus_tag="ACZPB4_04395"
                     /EC_number="3.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0006596 - polyamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase"
                     /protein_id="HIR1097494.1"
                     /translation="MKVGLIQQKNTADRAANIEKLKVNIRKAAREGAELVVLQELHNG
                     LYFCQTEDTSMFDLAETIPGPSTETFGALAKELGIVLVLSLFEKRAPGLYHNTAVVLE
                     KDGTIAGKYRKMHIPDDPAYYEKFYFTPGDLGFEPIDTSVGRLGVLVCWDQWYPEAAR
                     LMAMRGAEMLIYPTAIGWESSDTQEEKDRQLGAWVTIQRGHAVANGLPVISVNRTGHE
                     PDPSGQTGGIRFWGNSFAAGPQGELLTVFPNDEEEVRVIEIDKTRSENVRRWWPFFRD
                     RRIDAFGGLTERFLV"
     gene            complement(34032..35060)
                     /locus_tag="ACZPB4_04400"
     CDS             complement(34032..35060)
                     /locus_tag="ACZPB4_04400"
                     /EC_number="3.5.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016813 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds, in linear
                     amidines [Evidence IEA];
                     GO_process: GO:0009446 - putrescine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase family protein"
                     /protein_id="HIR1097495.1"
                     /translation="MEHNVILPAEWYPQSAVQLTWPHENTDWAPILDEVIPCFVAIAK
                     EVIKREKLLIVCPDETAVREQLGEVDYDRVIFREMDTNDTWARDHGGISVFDEGTPML
                     YDFVFNGWGMKFAANHDNLITRNLCHMKTFSGEVVPANMQPFVLEGGSIESDGKGTLM
                     TTVECLASVNRNEYLQQEELERYLKDVFGLDRILWITSGYLAGDDTDSHVDTLARFCS
                     EDTIAYVRCEDEEDEHYEELKAMEEEIKEFTRANGEPYRLIPLPMADKVEWEGERLPA
                     TYANFLIMNGAVLVPFYDSPKDEIAKAVLREAFPDREIVGINCLPLIKQHGSLHCVTM
                     QYPESFIE"
     gene            complement(35050..36399)
                     /locus_tag="ACZPB4_04405"
     CDS             complement(35050..36399)
                     /locus_tag="ACZPB4_04405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HIR1097496.1"
                     /translation="MTKQNSPLVLGTEPIGKLLTQYAIPAIIAMTASSLYNMADSIFI
                     GHGVGALAISGLALTFPLMNLAAAFGSLVGVGASTLVAVKLGQKDYEGANKVLGNVLI
                     LNVVLGVAFTIAFLFLLDPVLYFFGASENTISYARDYMRIILYGNVVTHMYLGLNAVL
                     RSSGFPKMAMYATLASVVINCALNPLFIFGFGWGIKGSAWATVISQVISLTGQLIHFS
                     GPKQLLHFKKGIYRLHSEIVKGILSIGLSPFLMNLCSCLIVILINRGLKEHGGDMAIG
                     AYGIVNRIAFLFVMIIMGFNQGMQPIAGYNYGARLYSRVTDVTRLTMRWAVGVATLGF
                     LLCQLVPSWIVRMFTSDGELISAASYGLHIVFAVFPIVGFQMVATNFFLSIGMSKKAI
                     FLSLTRQMLFLIPCLILLPPLFGTLGVWISMPIADTVAAIVTAIVLVKQFKQFKYGT"
     gene            36462..36938
                     /locus_tag="ACZPB4_04410"
     CDS             36462..36938
                     /locus_tag="ACZPB4_04410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HIR1097497.1"
                     /translation="MAEELRIKNGDKQEMYETLLPQIASLVGNETDLIANMANVAAAL
                     KQTFGFFWVGFYRVIDNQLVLAPFQGPIACTRIKYGKGVCGTAWKETRTIIVPDVDAF
                     PGHIACSSASRSEIVVPVIWEDKVIAVLDIDSDQPDSFDETDQIFLEKIVELLPHQ"
     gene            complement(37090..39969)
                     /locus_tag="ACZPB4_04415"
     CDS             complement(37090..39969)
                     /locus_tag="ACZPB4_04415"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0032508 - obsolete DNA duplex unwinding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HIR1097498.1"
                     /translation="MKPFLYQVASLFYEKWGAEVSRLAFVFPNRRTGLFFQKYLSEVA
                     DIPLFSPTILTINDLFIQLSGKQSADRISMLFTLYDIYIRQSGSTETFDEFLYWGEML
                     LNDFDDIDKYMANARMLFSNVTDLREIENDFDFLSDEQIAAIRSFWSSFYPRGDTPNQ
                     QQFLAVWQVLYDLYEEFRATLAAEGKGYEGMIFREVVESMERCESPDLPYEQIVFVGL
                     NALSVSEERFLAQLQKRKIADFYWDYVSDKVTDPDNKASYFVSRNRKSFPSSMKLPPE
                     EKVKTEIEVIGIPSGIGQAKHVYTLLSDWCKEAEMSSEEALRTAVILPDEHLLIPVLN
                     AIPEQIRRINVTMGYPLAGTPVASLIEYILALQKNVRYIDRNPLFYFRDVLPVLNHRY
                     ILSTSPEIISSLVKEITENNKIYISHTELGKTPLLEILFTPVTGVEAFSDYLIKVLEE
                     LNKVMSALSDEEEEDAPQRTNDLEQEFIFHYFTTVNRMKEVMKDARIEMKIDTFFRLL
                     KRVTDTITIPFHGEPLSGLQIMGVLETRALDFDRLIILSMNEGIFPQRKAANSFIPYN
                     LRRGFGLPTYEHQDSVWAYHFYRLIERASHVSLLYDTRSNGLQTGEVSRFVHQLHYHY
                     EVPMRDKLVVYNVSSSKTPPLAVPKREDIMRRLDAYRKGGSKAISASAINTYLDCPLK
                     FYFSVVEGIREEEEVSETIESDVFGSILHKVMEELYKPFQGKMVTVDLLKAIRKDTAL
                     LTGAIARAFASEFFKTEVVRSLTGQNYLIGEMIRKYVEKILERDGKLTPFVYIESERK
                     INGLISLSDYSEIRLKGFIDRVDEVRDAIRIIDYKSGSGTTTFSSIESLFNKEEKDRA
                     KAVMQVFMYCWMYAHLTENKGKTIQPGIYYVRSLFADPFDPSVYHRIERGKSEKVEDF
                     SGYAQAFEEGLRGCLDEIFNPEIPFTQTPTGKACSYCPFKGICGK"
     gene            complement(40039..41031)
                     /gene="mgrA"
                     /locus_tag="ACZPB4_04420"
     CDS             complement(40039..41031)
                     /gene="mgrA"
                     /locus_tag="ACZPB4_04420"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047834 - D-threo-aldose 1-dehydrogenase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-glyceraldehyde 3-phosphate reductase"
                     /protein_id="HIR1097499.1"
                     /translation="MEFYKAEENRYADMIYRRCGRSGILLPAVSLGLWHNFGSVDVFG
                     NFIQIAHAAFDHGVTHFDLANNYGPAYGSAEENFGRILKKGLGAYRDEMIISTKAGYD
                     MWPGPYGNWGSRKYLMASLDQSLKRMGLEYVDIFYSHRPDPETPIEETMGALADIVRQ
                     GKALYVGISNYDANQTRKALAVLKEHKVPCLIHQARYSMFDRWTEPDLLPVLKEEGVG
                     MIAFSPLAQGLLTDKYLRGIPENSRAAKSTGHLQTSQVTPEAVEKARKLNEVAARRGQ
                     TLAEMALAWLLKDERVTSVLIGASSVAQLMDNLKALDNISFSGEELQEIENILI"
     gene            complement(41054..42586)
                     /locus_tag="ACZPB4_04425"
     CDS             complement(41054..42586)
                     /locus_tag="ACZPB4_04425"
                     /EC_number="3.1.6.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase"
                     /protein_id="HIR1097500.1"
                     /translation="MKKTQLIPIALLSVSAVANAQSASRPPNIILFLVDDMGWEDTSL
                     PFWIQKTHYNEVYETPNMERLAKGGMMFTQAYASSISSPTRCSLITGTNAARHRVTNW
                     TLFKDKTTDRESDVLTLPDWNYNGVAQVSGTNNTFVGTSFVQILKNNGYHTIHCGKAH
                     FGAIDTPGENPHHWGFEVNIAGHAAGGLASYLGENNYGHTKDGKPYAPNAIPGLEKYW
                     GSDTFATEALTQEAIKALDKAKKYNQPFYLYMSHYAIHIPIDKDKRFYQKYIDKGLTA
                     KEAAYAALIEGMDKSLGDLMDWLEKNGEADNTIVIFMSDNGGLSSEPGWRDGEIHTQN
                     YPLNSGKGSAYEGGVREPMIVRWPGVVKPGSKCDKYLIIEDFYPTILEMAGIRGYKTV
                     QPIDGVSFMPLLKGTGDPSVGRSLFWNCPNIWGNDGPGIGPTCSVRNGDWKLIYYYET
                     GRKELFNIPEDIGEHNDVARQHPDIVKRLSGELGTYLRKVDGQRPSFKATGKPVPWPD
                     EI"
     gene            complement(42768..43229)
                     /locus_tag="ACZPB4_04430"
     CDS             complement(42768..43229)
                     /locus_tag="ACZPB4_04430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4293 domain-containing protein"
                     /protein_id="HIR1097501.1"
                     /translation="MLQRIQTVYLLIIVVLTVATLFLPLAVLQQGDALFSFDASGLST
                     MIGEPELLYPAWGLFALTAIIAIIALVTIFLYRKRILQIRLCVFNALLILGFYGFFAF
                     LIYSLKGDMEGASVSVKIALSFPLVNLILDYLAIRNIGADEALVRSLDRLR"
     gene            complement(43306..43638)
                     /locus_tag="ACZPB4_04435"
     CDS             complement(43306..43638)
                     /locus_tag="ACZPB4_04435"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007658146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000428 - DNA-directed RNA polymerase
                     complex [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed RNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HIR1097502.1"
                     /translation="MDYRKSNAPTNTVTRDMMKLSEETGNVYETVAIISKRANQISVE
                     MKQDLEKKLQEFASYNDNLEEVFENREQIEISRYYEKLPKSTLIAAQEYEDGKVYYKN
                     PAKEKNNF"
     gene            complement(43663..44472)
                     /locus_tag="ACZPB4_04440"
     CDS             complement(43663..44472)
                     /locus_tag="ACZPB4_04440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamD"
                     /protein_id="HIR1097503.1"
                     /translation="MKKVVFLLMMMTVLLSSCGEYNKILKSTDYELKYSYAKKYFNAK
                     QYSKSATLLDELVTIFKGTAYAEESLYLLAQSYYGQKDYQTASQYFETYYTTYPKGEF
                     TELSRFYSGYGLYLDSPDPRLDQSQTYKAIEQLQLYLEYYPQSERAEEAQNIMFELQE
                     KLAYKELMATRLYFNLGTYMGNNFQSCVITAQNALKNYPYSKYREEFMFLIIRAKYEL
                     ALVSVEEKLQGRYRDVVDEYYNYMNEYPEGNYVKQVTKFYDYASKRITDAY"
     gene            complement(44539..44964)
                     /locus_tag="ACZPB4_04445"
     CDS             complement(44539..44964)
                     /locus_tag="ACZPB4_04445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid-binding protein"
                     /protein_id="HIR1097504.1"
                     /translation="MLIKQLSIFLENKKGRFTEVAKILGEAGVNMSAFTVAENSDFGI
                     LRLIVSDTEKAISVLREKLYAVSVADVVCLHCPNQPGALAKAMDIITSAGIFIEYMYA
                     FSQGDAANVIIRPDDVNKCAEVLKANKLELIAASDLYKL"
     gene            complement(44985..46286)
                     /locus_tag="ACZPB4_04450"
     CDS             complement(44985..46286)
                     /locus_tag="ACZPB4_04450"
                     /EC_number="6.2.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047475 - phenylacetate-CoA ligase
                     activity [Evidence IEA];
                     GO_process: GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetate--CoA ligase family protein"
                     /protein_id="HIR1097505.1"
                     /translation="MIWNETIECMDREEMRKLQSLRLKRVVEHAYHNSPFYRKKMQEM
                     GIAPDDIQTIDDITKLPFTVKQDLRDNYPFGLMAVPMSEIVRLHASSGTTGKPIVVGY
                     TRKDLGIWAEVVARCLTAYGLTKNDSVQVSYGYGMFTGGLGAHAGVENIGGTVIPMSS
                     GNTQKQIQLMHDFGAKGLACTPSYALYLAETIHQSGIPLEEFQLRVGAFGAEPWTENM
                     RKELETKLNIKAYDIYGLTEICGPGVGGECECQNGTHLWEDHFFPEIVDPNTLQPVEP
                     GQVGELVFTTLTKEGMPMLRYRTRDLTSLTYEKCACGRTAVRMGRILGRSDDMLIIRG
                     VNVFPSQVESVILELPEFEAHYLIVVDRMNNTDTFQIQVEVRQEYYSDEMNKMIALKK
                     KIAARMQSVIGLQPDIKIVEPRSIERSMGKAKHVIDKRKLV"
     gene            complement(46393..47202)
                     /locus_tag="ACZPB4_04455"
     CDS             complement(46393..47202)
                     /locus_tag="ACZPB4_04455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-disaccharide hydrolase"
                     /protein_id="HIR1097506.1"
                     /translation="MKTLVICTAMSAMILCACGGKNTQSTEETAKVVPMAVITPAINQ
                     LTDQEKAEGWALLFDGKTTKGWRGAHKDAFPDHGWMVKDGELIVQKSDGSESTNGGDI
                     VTEGEYSAFEFSVDFKITEGANSGIKYFVTEQEKQKGSAYGLEFQLLDDAKHPDAKLY
                     TTFPGSRTLGSLYDLKKSENIHFNGVGEWNTAVVKVFPNNHVEHWLNGVKVLEYERGS
                     KEFRDLVKGSKYADPSYNAGGAFGEAPKGHILLQDHGDEVAFRNIKVKELK"
     gene            47313..47951
                     /locus_tag="ACZPB4_04460"
     CDS             47313..47951
                     /locus_tag="ACZPB4_04460"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HIR1097507.1"
                     /translation="MKQPKTALFDFDGVVVDTEPIYDLFWNDAAKRYGLGIDNFADII
                     KGTTLPYILEKYFSGYTEEFRQMVTKESTEYEKTMPLPPMPGSIEFIRMLKEHGVQIG
                     LVTSSDNAKVKRAFRLLHLDNLFDTLVTADRITQGKPDPMCYLLAAKDLNVSPEDCIV
                     FEDSFNGIQSGKDAGMRVIGLSTTNPAESLRDKVYEVIPNFEKVTFEDYLRW"
     gene            complement(48192..48674)
                     /locus_tag="ACZPB4_04465"
     CDS             complement(48192..48674)
                     /locus_tag="ACZPB4_04465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0015288 - porin activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="porin family protein"
                     /protein_id="HIR1097508.1"
                     /translation="MKKFVMMLMLAVFSLGAYAQTQQGQSAVGFNIGYGFDSKNATLG
                     VDYRYCITDAVRLSPSLTYFVKNDNHSTWAIDLNAHYVVKLSEMFGFYPLAGLSLSFW
                     NWDAGHGLSHNETRLGANIGLGGEVYATDNLSIGLEVKYNIIKDFDQAMLGVRVGYSF
                     "
     gene            complement(48718..>49374)
                     /locus_tag="ACZPB4_04470"
     CDS             complement(48718..>49374)
                     /locus_tag="ACZPB4_04470"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016805 - dipeptidase activity [Evidence
                     IEA];
                     GO_function: GO:0070004 - cysteine-type exopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C69 family dipeptidase"
                     /protein_id="HIR1097509.1"
                     /translation="WRPMTFEVDGQEYTNERAIATQQTGFVIVPQMRNWLPDAIGGIL
                     WFAVDDADMAVFTPVYGSVTDVPECYRVGNGDLLNFSWTSAFWIHNWVANMAYHKYSF
                     MIQDIRKVQQELENGYQETVPAIDKAAQELYAKDPAEAVKFLTWYSTTNSDSATARWK
                     QLGEYLLVKYIDGNVKKEVNGQFKRNPYGQPASPDFPGYDEDYYRSIVKSAGDRLKVK
                     "
BASE COUNT        13320 a        13118 c        10699 g        12137 t
ORIGIN      
        1 aggtatgatt tcaaatcgtc gcgcctaaaa agtagtatct aatagactat atttcaatta
       61 tttcaaagaa ctatttatcc acttttacgg gacagtaatg tgtgtatgta tttaaatgtt
      121 ccaaggcgct ctcatcggct gatccaacaa acgattagcg gcctcatcat taataaattc
      181 cagttttacg ggatcaaagt gaagcgtacg attcaaacga agggctacgg cacccatatt
      241 cacgatcgta gcggaacgga agccattacg ctcattcaag gcaaaaggct gacgagtctt
      301 tacgcactcg ataaagtcgg taacctgtgg ctcaggttcg ggataaccgg ataacttttt
      361 ctcccaatcc gggatatcac atacgaaatt cttataaaca ttcccgttcg gtccggaaat
      421 ataaggtgtg ttcggatccc cgtaatcacc tccccaaagt acgatctggc aaccatcctc
      481 ataggtatac gtaatcgagc gccaagtacc cacggcgtcc ggatgttgtt gcggagcatc
      541 cacctctacc ttaaccgggc tggtattatc ttttcctaga aaatattgta cagggtcaat
      601 ataatgctgt cccatatccc ctaaaccacc gccgtcataa tcccagtatc cacggaatgt
      661 ctgatgcaca cgatgcgggt tataaggttt gtaaggagcc ggacccaacc agaaatcata
      721 atccagctca ctaggcaccg attgtggttc cagatattct ttaccaaccc aatagaactt
      781 ccagtcgaaa ccggtatgct tgctgatcgt tacctttagc ggccagccca acataccact
      841 ttgaaccagt ttcttcaaag gtttcactgg agtgcccagt ccatagaacg ggtcagcgaa
      901 acggaaccaa gtgttcaagc ggaacatacg tccgtattgc ttcatcgctt ccattacccg
      961 tttaccctcc ccgatcgtac gggtcatagg cttctcacac caaatatctt ttcctgcttt
     1021 agcggcctcg acagacatga taccatgcca gtgaggaggc gtagctatat gaacgatatc
     1081 tacattggga tctagaatca aatcacgaaa atcatggtat gcggcaatct tatcctttac
     1141 caactgttta cctagctcca gatgattctt atcgacgtca cacacagcga caagacgagt
     1201 cccggcatag tccacatgtc cacggcccat accacctgta ccgataattc cttttgttaa
     1261 ttgatcactt ggagcgatga atccattacc caacacgtgg cgcggtacaa tcgtaaatgc
     1321 cgcgattcct ccaagagtct tcaggaagtc tcttctgttt gtcttcatag tacgaattta
     1381 aaatttagat agaatagatt aacttgagtg acaaaaataa tcataatact cgaagagaca
     1441 agaaaaatgt atataaaaaa gaaaaggatg cctttaacaa agacatcctt ccctagtatt
     1501 ttatgaaaat ctattacaaa gcgaattgcg gttgacggtg aatccattgc ccacgggtga
     1561 aatccgggaa gtctaccaaa gcaccgccac gagcgattga catctccgac aagccggaga
     1621 tagcgctcca agcggcagcg tcatagcaat ccattggagc cggtttctta ttacggatag
     1681 cgtcgatcaa gtcgtacatc atgatatagt ccataccacc gtgtccggcc tcagcagctt
     1741 gagactctaa ggaagcccac aatttatgat catatttctt gaaccattca tcggaatcat
     1801 cccaacgatg aggcttagac tttccttgta catatacatg atcgccatcg ttcatccata
     1861 aaccctcagt tccctgaaca cggaaaccta atgaataagg gcgaggagaa ttggtatcat
     1921 gggttacgat aatcgtttgt ccattagaac acttaatcat agaagtcacg atatctccca
     1981 aattgaagtt gaccttcgcc aacggatgat tctcaccccc attatccacg ataaacttat
     2041 gcaatccacg agattgagta gccatagcgg ataaagaaag gaaacggtta ccacgattga
     2101 tatccataca atgagctatc ggtccgatac cgtgagtcgg atagatatcg ccattacgat
     2161 gtacggaatg gttcgtacgc cattgagcct cggcgaaagc cgtcggaccc atacgaagat
     2221 caccactgcc cggtacatag ttgtaatgag ttccatcgtt gaatttcacc tcacgcaagt
     2281 catgctcata accacaacca ccatgcaaga tctcgccgaa caaaccttgg cggaccatat
     2341 tcaacgcagc catacagtca cgacgataac atacgttctc catgatattc aaatggcttc
     2401 cggttgcttc cgaaacattt accaaatccc agcactcctc taacgtgtta gccgcagaaa
     2461 cctccacgcc tacataagga acaccagcct tcatagcggc gacagacatc ggtacgtgcc
     2521 attcccaagg acttgcgatg atcacgcaat caaactcctc gttgttcaac atattctcaa
     2581 attcacgttc accccctttg taaactttcg gagcagggac attaaattta gcgatatgtt
     2641 tcaaggtact atcgatcggg ccctgttgga tatcgcaaat cgctacgatc ttattaccgg
     2701 ggatcgccaa tacattatta atatgctcat ggcatctaga acccgttccg atgaaaccga
     2761 aacgtaattt accatcatct ttaccggctg tttttttctt ttggggttca gcggcagttg
     2821 ttgtagctcc ggcgtttcca gccattgcca agcctgcggc accaatacca gcggcagata
     2881 ctttcttaag gaatgaacga cgagtgtttt ccatatattt tataaattag tttgtgtttt
     2941 gaggatacaa aattaaaaaa atattttttc aatcaaaacg ttattgagta ttttgaaaaa
     3001 taaagagtcc aagactaaaa gttcgttatc tttccggttt ccctttttag cctctcgaag
     3061 gtcatcatca tctgtcgaag tcttttaggt tctttttccg ccaaattaac ttgctgaccg
     3121 atgtcttcct ttacattata taattgataa cagttactat ttccggcaaa ggcagcctcc
     3181 tctgcgtcac cataggtatc cggatacggc gggatcatga cccaatcacc atcacgtagc
     3241 gcataattga aataaccttc caagacaagt tcctttcgcc cattaccacc ttttcctaga
     3301 aagacaggca aggtgttttg gctatctacc ttatcagaat aggtctgtcc gatcaacgcc
     3361 gacagcgagg ctaacaaatc catctggcaa accaaggcat ccgacacagc gcccggctta
     3421 acttccgcag gccaacgaag catgaacggg atacaggtcc caccatcata caagctcgtc
     3481 tttcctccac gaagcggtcc ggccatctta tgatccccta ccaattccac ggcttgatct
     3541 tgataaccgt catccagaac cggtccgtta tcgctagtga aaacaactaa cgtattttcc
     3601 gttagcccca acttatccat ttccttcaag aattcggtca cgcaccaatc cgcttccaag
     3661 ataacatctc cacgaggtcc catccccgac ttacccgcga atctctcgtt cggaacacga
     3721 ggtacatgcg gttgatgcaa gccatagtac aggaagaaag gtttatcctt attctctttc
     3781 ataaaacctt tcgccttctc aaggaacaac tctgccatat cctcatcttt ccattgggcg
     3841 gtcttgcctc ctttctggaa accaattcga ggtacaccgt ttacgatagc gccggcatgc
     3901 ccgacactcg ggagcattct cagtaattca ggattatcct tcccagtcgg ttccccgggg
     3961 aaattctcct tataactgac atagagagga tcgttcggat cgaggtttac acctctccca
     4021 ttctcgataa agatacaggg aacccggtca ttagtagcag cttggataaa agaatagtcg
     4081 taaccgatct ctttcgctcc gggataaacc agcttgttcc agtctaccac cccgtcacct
     4141 aatcctagat gccatttgcc gaccgagccg gtgacatagc ccgcttgctt catcaccttc
     4201 ggcaaggtaa cctgttgagt attgataatc agagccgcat tgccgggaag tattttggca
     4261 tccctatttg tccaaggata taatccggta agcaaggaat accggctggg ggtagaagta
     4321 gccgccgtac aataaccttg cgtaaagcgt atgccttcat ttgcgatacg atccattccc
     4381 ggagtctgta tgcgatgagc cccgtaacag cttagatcac catacccgag atcatcagcc
     4441 acgatgatca ccacgttagg ttgccgggga gctgattgag ctattaaagt tgttggcaag
     4501 gaaaaccctg ccaacacact cattatacaa tacttattca tcgcttatta cggattctga
     4561 gttaatgtac ccggataagc gttaatctca gactgcggaa tatactggat agccaacggg
     4621 ctggtagcag gatattcagg cacgccgtca tggaatcccg ggtaatgacg tttcatcgta
     4681 tcgcctacac gatatacatc aaaaccacgg tcagcctcat aagctaattc caactgacgt
     4741 tctttcatga taagctcatg agcgtttgtc gcatccaaag atttatatcc ggcgttaggt
     4801 aaggaacggg tacgaacggt attcaaatcg gctaatgctt ttgtatagtt tcctaattta
     4861 gcgctagcct cggcgcgaat caggtataac tcacctaagc gagagataac cggtgaataa
     4921 aggtggggat aaccttcttg cttagagcat ttataactat agaatttcgg attaccttgg
     4981 ctttctaaca tcaggtaatc ataatcaccg acataagttt ttcccttata actaatagaa
     5041 taacgtttat tatccacatc tacgggagtt aatgtgtact cttcatcatc cacggtagcg
     5101 attaacttac cacctacttc ctttgtctca ccctgacgat atacataacc ggaaatcttt
     5161 ccgtccgtat acaagttagc gacgaaacgg aaagccggaa tttgatctcc cgcatcattc
     5221 ttcttatatt gtggatggat aaaagcctcg cgggcatccg tatttttacc tgtctcatgc
     5281 agcaaatcca tgtatttagc gctagcgtat acctcacccc agccttgacc atcaatctcc
     5341 gcatacatac tacctaacgg gctaccccaa tcatcccaat ccgaagcaat gaatttcacg
     5401 gcaaaaatag tctccgtttg agaagccgca tccggagcaa gctcattata tgtcataaac
     5461 gtcgaacgac tcaataagga gaattgatta ctctcgatta cctcattcgc ataattataa
     5521 gataattgag cgtattcctt attcggattc tcaaaagtac cactcatata catataaacc
     5581 ttggccaaca aggcttgagc cgcatacttt gaggcatagg cgggcgactt aaaatcagac
     5641 atcaactctt ctgccttttt caagtcagac agaacttgct catacgtatc tttcacggaa
     5701 gaacgatccg gaagatccag gttatccata tcctcaggca taccattcac aataggtaca
     5761 cccagattct tctccggttc ttgataataa ggacggccaa acacacgaca cagataaaaa
     5821 tacatcatgc cacgcatata ataggcctca cccaactttt ggttcaactc tggagattca
     5881 ttctcattga tcatcttcat taaagaactt gtctgcgaga tgatattata agcactgttc
     5941 caaaccgtag aaagcccacc attattaacg gtatgctgat aagtaaagta agtaccgaat
     6001 ggatttgtgg tcggcttatc cttgcaaacg ttatccccgg ggaactctcc acaatagtgt
     6061 aaatgctcag atgcagtttt caatttagcg tagcaaccgt ttaataagac atcaaccgca
     6121 gcatccttat cttccatgat cttgtcctcc gtatacttat cataaggcat acgttcgata
     6181 tcacagcttg ttataaatgt ggccgctgcc gcaagagcca ctatagctat ttttttcatt
     6241 cttattcctt taattaaaat gtaacattta aaccaaacat aaatttacgg gcttgtgggt
     6301 acggagaaat ggccacacca accgaaccag ccttgtattg gcttcctacc tcagcaggaa
     6361 gttccggatc cactccagag aaacccgaaa gaacaaacaa gttctcaccc gagaaagaaa
     6421 gacggacatt gtctacatat tggatcttcc aaggtaacgt atagcctaat gtcaagctac
     6481 gcaaacgtaa atagctcgca tcctccaagt aacgggaaga tcccttgctg gattggctct
     6541 tattaccata ttcagctttt ggatgggtag cgatatcgcc cggtttttcc cagcgattcc
     6601 aatcatccct taaattcatt tgattatagt ttacataagc accatcacta tcatacatag
     6661 aacggtcata attgtaaatc tcacctccta ccgaataacc gaagactgcg gataaatcga
     6721 tattcttcca agatagattt gtagagaaac caccgtagaa gtcagggctt aattttccta
     6781 atatagtctg gtgcttggaa gcctcgctat aatcagaagt tgttatgcgt tctcctttct
     6841 catttgttgt ataccacaac ggagctcctg tttgcggatc tacgccagcc cattcagttc
     6901 cataccaagt atccacatcc tgacccggag tcaagatctt atccatatag atgtaatagc
     6961 ttgttcctgc gttggcagta ataatctcgc tcttaccacc atacaattct gtgatcttat
     7021 tacggttcaa gcccaagtta gcggcaacgc tccaattcca atcaccacct ttcaagatgt
     7081 ccacacctaa tgaaacctcg aaaccattat tcttaacaga accaacgtta cgatagatac
     7141 ccgtgatacc tgtcacaccg ggcagaggca ctttataaag caaatcggtt gttttcttat
     7201 tgtaataatc caaattaata gtcagacgat cgaacaagat agcgtcgata cctacacccg
     7261 ccgtataggt tttctcccat gtcaagttct tattttcttt ttgagcaatt accgcacccg
     7321 gatcaccgtt gtatcccgta gacatagcat acaaagtata ctgcgaatac agctcagtag
     7381 gacgattacc tacagaacca tagctagcgc gcaacttcaa ttgctgtacc caatcctttg
     7441 ccttgaaaaa ttcctcctga tggatattcc aaccaccact aacagagaag aaattaccat
     7501 atttagcatc ctcaccaaag tttgaggcac catctcggcg gaaagagaaa gacaataaat
     7561 aacgattgtc atacgcataa ttggcattga acaaatagga ttgtacagcc cattcctctt
     7621 gcgatccttt tattgtctta ggagttgtcg ctacatctgc cacggagaaa cccggagcga
     7681 aactagccgc tgtctgatcc ttgatttccc gggtataaga gttccactca taagccaata
     7741 tcgcattgat ggaatgttta tcgaacacct tattaaaacg aagcaattgg ttgctatata
     7801 cccgataaga agttgtggtc ttatcttgca acaatccatt gtcggcctct cctgccttag
     7861 agcgaggatc gttatagcct ttgaaaagaa tgttattata tttatagcta ttcacggacg
     7921 caaaagtcaa ccaatcggta aacttgatat cgaagtcaaa gtttcccata aactcatagg
     7981 aagttttctt ctcataattc cattgcaggt catacaagta atttgtagca tcgctattca
     8041 cccaatcggt cggcctgtat tgctggatca agtcgccatt ctcgtcatac ggggagtccc
     8101 aagggaaatt aacgtacatg atagcgccta gatcttgctg ctggtccatc acgtcgctac
     8161 gggtagccca tactttaggt ttgatagtca accaatccgt cgcttggtaa tccacattga
     8221 aacgcaagtt ataacgcttg tagtcatatc ctttcacggc accatcctca ttatagtaac
     8281 caacggatgt atacgtcttg atcttctctg agccaccgga aacagatacg ttatagtctt
     8341 gagcgaagcc cagatgcgta ccctctttcc accagtcgaa gttacggttg cgcaaatcct
     8401 ccgtaaaata actcggaagg gcgtcttgat tagcgaaaga tttataataa tcatataatt
     8461 cctcgccgtt catcatattc atgtttccac ggtgcaactg gttcacaccc atctttacgg
     8521 aagcgttgat cgtagctttt ccgatcttac ctttcttcgt agtcaccacg ataacaccgt
     8581 tcgctccttg agaaccatag atagcggttg aagcggcatc cttcaagata gacatggatt
     8641 cgatatcagc cgggttcaag ctacccgcat ccgtaccgac gattacgcca tccacgatcc
     8701 aaagagggtc cgtgctaccg tttaccgtag acttaccacg gatcaccacc ttaccggcag
     8761 cgcccggctg accaccaccc gaagtaacct gcacgcccgg agccttacca gacaataagt
     8821 tctcgaccgt agggctagtg gcatccaaca atttctcgtt gctcaccacc tgcatggcac
     8881 ccgtcaagct ttcctttttt tgcacgccgt aaccaacaac aaccacctcc tcaaggttct
     8941 gagtgtcttc cttgatacgg atagtcatcg gagcactagt cgctttaacc tcatggttca
     9001 cataaccgat gtaagaaacg accaaagtag ctccggccgg agcttccaaa ctaaactttc
     9061 catcgaaatc ggtactggta ccgttcgtag tgcctttcac aagcacgttc gcgccgatta
     9121 ccggctcacc cgtcaccgcg tcaacaatgg tacctgaaat cgtaatcgtc tgctgcgcca
     9181 ccattctctc cgtgtttctc aattcatttg gattagaaga tgacttgtaa acaacaatcc
     9241 tattgttgtt tacaacaaaa tcagcatgct gatttttcag cgccgtcgtc aaaatctcct
     9301 cgaccgagcg gttcgacatg tcgattgaga tacgctcatt cagattgatg tcattgttac
     9361 ggataaggaa cgtgtaattg aatttttcct cgatcaaatc gaaaagttct tttaatgtcg
     9421 tactttccat ttgaacagac atcatttgtg tctgaagttc ggacgctgaa accgtaccgg
     9481 gaataaacgg cagtcccgca agcatacatg cggctaccat catcttaccg gtcttcttga
     9541 aatagttcat ttccattaaa gttagattta ataaataatt ttctcgttta tactattttc
     9601 cacacttaca ccttaggatt aaggtttgta tttttgtttt tacttatctt ttataataat
     9661 ctcatctccc gaacgagtcc acacatattt atgatccacg tccacctcac gaaggatctt
     9721 atccaacgaa taatctttcg taaagctacc ggagaagatt tcctttctca aaagatcgct
     9781 ctcgacacga atacgcacgt tgaacttacg ttccaaatcc ttggcgatac tcatgaaagg
     9841 ttgctcggag aatttcaggc taccgtccat ccaagagaga gcatccttgg catccacctc
     9901 actgactctt accttattgg tctgcttatt aaagcttagt ttccggtttg gagtcaaggt
     9961 cacatcgccc gcatgggcaa cctcatcccg caagctcacg tttacttttc ccgacaccag
    10021 agtgacatcg gtcatttcat ccattccgta agcctttacg ttaaatctag ttcctagaac
    10081 cttgatatcc aacttctttg attttacgat aaaaggctta agggaatccc gggtaatctc
    10141 gaagtaagcc tcaccatcca attgtacgct acgtccgttc gtattgaaat cactgccata
    10201 tctcaacgtg gaacctgcgt tgacccaaac cacggattga tccggcaaaa cgactttcgt
    10261 ttgggctccc ataggagttg tcgtctcaaa ataagccaag gcggcagatt tcggctgatt
    10321 atgtctcgta cctatataat aagaggcagt tcccaccgat accacgatca agaccgaggc
    10381 ggcaactttt cctaaaaacc gaaaatttag ccaatgattc ttttcagaag gaatagcggg
    10441 atcgataagt gccccgaaat gtttttggaa atcggctttc atatcagagg caaacaaagg
    10501 tacatgcgcc gtcgcccaac aatctgccat ctcggaaagg cactgtttat gagcgtcatc
    10561 cgtttccaac cattgtagta attcatttcg cccctcctcg gatatatctc ccatgaggta
    10621 gctataaatt aaatcttcta tgtgtttatt ctctatttcc atgatattaa caaaggagcc
    10681 ggttttcaac ccggtttcta ttatatacac ctgttttaga gattccgttt aaggagattc
    10741 caattatttt tcgaaaaaat taaatataag taagaaaaga gggtaaagat cgcctaaaag
    10801 ttcacgcaac ttcgccaaac cgatcttgat ctgtactcgt accgtactgg aactgatatg
    10861 atttgttatc gctatttcct cataggtctt gttatggtaa agatattgca cgaagatatc
    10921 ccggcattta gcgggcaagg aatccacggc acgatagatt ttctcctcga attccttatt
    10981 ctccagataa gccaacggat gggggtccgc gtcgatttgc aactcttgta tcgacaataa
    11041 gctttcttgt acatctgata aagggacttc ttgctgacgt ttatctctta aataattcag
    11101 gcaataatta cgtaccgagc gaattaaata agcgtttacc ggatgtatta acgccgaatg
    11161 gtgattccat acattcataa aaacatcatt aacgatctca cgtgccgcct ccgaattata
    11221 gacatattta gtcgctacgg cgcacaagta cacgtagaag gtcgtatata attgttcaaa
    11281 tgctttggca tcgccattat tgatccgaga tattatgtcc tcctttacaa tcagcacaaa
    11341 cgtcaaccct taagtttcac tcacaattga atcacaaaaa taatgaaata ttccagagat
    11401 tacctcattt taaaagaaag tatagggtaa tagcgccaaa cagctcgcta aagcggactg
    11461 tttggatact taggtgacga accggatgcc atacgggtgg catagctgtg ccatccttgt
    11521 ggcacgccct tgctatcctt gtggcactgc tatgccaccg gcgtggcacg actgtgccaa
    11581 tgctatggaa aggactgaca ctatacgtcg ttacaataca acaacttaga ttacttagaa
    11641 gaattggcgg cannnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    11701 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnatgccacc
    11761 ggcgtggcac gactgtgcca atgctatgga aaggactgac actatacgtc gttacaatac
    11821 aacaacttag attacttaga agaattggcg gcacgcttct tgttacgcca gtaactaccg
    11881 tcacgtttgc ttccgaacat attacggcgt ttcgactctt gcttgatcgc ttctttcttc
    11941 tcggctacgg cggctttcac ctccttggtc tcatacatat ggccaccggc tatggggact
    12001 tccttgccga tcagtttctg gatatctttc aacaaaggta cctcctcggc gtcgcagaaa
    12061 gagaacgcca caccttcacg gcccgcacga cccgtacgcc cgatccgatg tacataagtc
    12121 tcgggtacgt taggaagctc atagttaatg acgtgtgtca gatgatccac gtcgattcca
    12181 cgggcggcga tatccgtagc gatcagcaca cgggtcgtat gatccttgaa attcgtcaag
    12241 gcacgctggc gggcagtctg gctcttgttg ccatggatcg cctccgcccc tatctccgct
    12301 ttcgacaaga cacgggccac cttgtccgcc ccgtgtttcg tacgggtaaa gatcaatacg
    12361 gattctagtt ccgggttctc caacaagctt ttcagcaagt tgatcttctc ggccttctcg
    12421 acgaaataaa cggattggtc gatcgcgtcc acggtcgatg aggccggggt tacttccacc
    12481 ttttgcggct cgctcaagat cgtacctgcc aagcgctcga tctcaggggg catggtagcg
    12541 gagaagaaca aggactggcg tttcttgggc aatagcggta aaatacgctt gatgtcatgg
    12601 ataaagccca tgtccaacat acggtccgct tcgtctaaga cgaaatactc caaggtatcc
    12661 aagtggatga atccttgtcc aatcaagtcc agcagacgtc ccggcgtagc gattaatata
    12721 tcgatgcctc tttccaaggc ttccgtctgg ggcttttgcc ctactccccc gaatatcacc
    12781 gtatggcgta atccagcgaa acggccgtaa gcggcaaagc tctctccgat ctggatggca
    12841 agctcacggg taggcgtaag gatcaatgcc ttgatacccc gtttgtaacc tttcttcttc
    12901 tggagatata accgctggat aatcgggatg gagaaggccg ccgtcttacc ggttcctgtc
    12961 tgggcgcaac ccaataaatc ataaccttgc gaaacgatgg gaatcgcttc tgattgtata
    13021 ggtgttggag tcgtataacc ttcttgcacg agagccttac gtatcggctc tatcaaatct
    13081 aaatcttcaa atgtcattct aaaatagggt gagccatcac ggctcgttat gtaaataatg
    13141 tgggcaaagg tagtaaaact ttatgatata aactatcttt gcgcttttta tgcccgtaaa
    13201 gcgatatgaa agaattatta ctactactga aaaagttctt cggatatacc tccttccgtc
    13261 ccttgcaggc ggacatcata cagcgtatct tacagaaaga ggactcgttg gtgctgatgc
    13321 ccacgggtgg aggcaagtcg atctgttttc agctaccggc tatctatctg ccgggtacgg
    13381 ctttggtggt gtcccccttg atcgccttga tgaaggatca agtagaggga ttgatcgcca
    13441 acggcatccc tgcggcggcg ttgaacagta tgatgccgga agaggagcaa caacaggtga
    13501 agcaactttg cgtgcagggc aagatcaaat tattgtatat ctccccggaa cggatcaaga
    13561 tggaggcgga ctggttcctg ccccggctgg acatctcgct catcgctatc gacgaggcgc
    13621 attgcgtatc gcattggggg catgacttcc gtccggaata cacgcaactg gcgatattga
    13681 aggaacgttt cccgaaagtc ccggtcgtgg ccctgaccgc taccgccgat aaaatcaccc
    13741 ggaaggatat cctagagcag ttacggcttc gcgagcccca aacgttcata tcgtcattcg
    13801 accgcccgaa catctccctc acggtacgcc gagggcttaa caagaaagag aagatcgccg
    13861 ccatcgtcca tttcatccgg gggcaccggg agcagagcgg tatcatctat tgcatgcgcc
    13921 gcaacgatac gaccgagctg gccgatgagt tggcgatgta taatatcaag gcgatcgcct
    13981 accacgccgg cctcctgccc gcccaacggg aacaggccca aaacgatttc atcaacgacc
    14041 gggtggacgt ggtgtgcgcc acggtagctt tcgggatggg tatcgacaag agcaatgtcc
    14101 gctgggtcgt gcattacagc atgccgggga gtatcgagaa ctactaccaa gagatcggcc
    14161 gtgccggaag ggacgggatg aaaagcgatg ccctcctgtt ctattccttg agcgatttga
    14221 tcgtacttcg ccgtttcgcc gaggagagtg gccaaagcga ggtgaacttg gagaagctaa
    14281 accggatgag acggtattgc gagtccgata tgtgccgccg ccgtgtcctg ctcagttatt
    14341 tcggcgagga ggcggaccat gattgcggca actgcgacgt gtgcaagaat cctccgcaac
    14401 gtttcgacgg cagtgtcttg atacaaaaag cgctgagcgc cgtcatccgg accggcgagc
    14461 atgtaggcat gcaaatgctg atcgacatat tacgtgcctc cgcccgtgcg gagctgctgg
    14521 agagaggata cgataagcta aagacgtacg gagccggacg ggatctctct tataaagaat
    14581 ggaaggagta catttaccag atgatccaac tcgggtacat ggagatcgac tacgccgccg
    14641 agcgtgtctt gcggatgacc ccgctaggca ggcgtgtcct gtacggggag caaaaggccc
    14701 agctcgtcat ctatcgggaa ccggatgagc tgacacgccc cgtccggaga ggcgagcgga
    14761 aatcctcctt caaggcccag ccgatccggc cgatccggtc cgcctctacg gacgagacct
    14821 tgctggactc cctccgccaa cttcgcaagc aaatcgccga gcgagagcat acgccggctt
    14881 atatcatctt ctccgacgat tctttggaag acatggtgga gaagaaaccg gtcaccttgg
    14941 accagttcag cgacatccgg ggcgtggggc aaatcaagct ggaccggtat gggaaggtgt
    15001 tcgtggcctt gatccggttc gtgctgaagc taccgaaata agaagaacac atgttaatgt
    15061 ttttagctcc taaatggaaa tataaaaaaa tcacatatat ttgtctacaa ttattaagca
    15121 caatgcctca tattcatgat agacaaacat ttttctctcc tcacccacct gctctgtctg
    15181 tgttttctgg caggatgcga gaatgagtat ttcaaaacgg ggagtatcca tatccaattg
    15241 aagaaacctt ccggatacgt agatatctcc ttggcgaata tcccggtcac actaatcaat
    15301 caaagtatag gctgtgtcta caccacgacc accgacacaa atggactagc tctatttgaa
    15361 ctaaccgctg gcatatgcgc aatctccgca aatcaggaaa ccacgactgg caacagggat
    15421 tatatattga gtggtagcct ctccaatatc cagttcgagg ccaatggaga agaacgatcc
    15481 gtggaaatac ctttggaagt gtccgaacga ggccgtctgc tgattagcga gatttatttc
    15541 agcggttgtc tctggcctga cgggaaaaat gtctataaca aagatcaata cctcacgttg
    15601 gtcaataact ccgatgactt gattttccta gatggcctat gtatcgcaca agcaggaccc
    15661 gtaagcgtga caaagccttc cggatggatg ctccataccg atatgaaaga aataccttta
    15721 ttcatgatgt gctgggagtt tccgggaacg ggaaccgaat atcccattca accgggggag
    15781 cgacaaacga tagcgattaa cgccataaac cataccaata gcgaagtggg agttccggcc
    15841 tcgctcgatt tatccagcgt ggaatgggct ttttgggatc ctatcttgac cggaagccaa
    15901 atctccgccg gtgtaaaacc tctaaacttg gtatggcgtg gcaccggttt ctcctatctg
    15961 ttttccatga acggcccgac gatcctcttg ttccgtccca aaacggactt aagagaatgg
    16021 atcgccaatc cggatcacat ccaaaaagaa cctgagagtt tcaatacgct aaaatacctc
    16081 catatacccg ctgattgggt gcaggatatc gcgaatttcg tctcttcaac ctctacggta
    16141 gcttacacac gtatcccatc ttctatggat gtgagtccgg gtatagccac gtccggcggc
    16201 tccggcctgg caatgcgtcg gaaatatgag caagagggga aacgcttccg ctggaaagat
    16261 tccaataaca ccgccgagga tttcgagaaa agtccacctt ccttaaaacg gtaagcctct
    16321 atgaagatca ctatcattct atatatgata tcactatctg tctatgcctc acggtcatgg
    16381 gctcaacaag agagcgcatg ggctttatcc gccaatcctg tcagcatcag ctatgtgcct
    16441 aaggacagcg ctatggaagc tggtttaagt tatttgatcc atcaagccgc cttacctgcc
    16501 agcgaccagc cggatcaaac acagacctat agggcttatg tatccggtaa ccgaaagctg
    16561 ggtctgcttt ggctggcggg tggtatcgat tggtcgcaaa gcctactgga agggagaaaa
    16621 tggaatttat tatcgcaacc ggactatctg attacggccg gcgattcctt gggagagcca
    16681 caacgcatcg agaaatacag gatctacgga caagcggctt acgtcttatc cccgaaaatc
    16741 aaggtcggga tagatggaga ctatacagct acaagcaacg aagatcgctc ctcttaccat
    16801 atctaccatg ggatggcaca cttaatccag atatcaggag gtatcgttta cgaacaagta
    16861 cgcagacgtt ttggagcctc gatccattat acccatcgaa cagaggaatt aacgtatgat
    16921 acggatagta aagataaact ttatacattt cctctgggtt attggcttcc gatgcaagaa
    16981 ttatcgggaa gtttcctgtt tcgcagccaa ggaaaacgcc taggtgtttc cttgcaaacg
    17041 gaaaccctaa aagagcattg gagtcttttc catgatctct cctacgagac ccagcaatta
    17101 gcggacaatc caaataactc cggcaacttg agaggctggg aagaacggct gcaccaaatc
    17161 tgttaccaag gtcgttttac ccgaacgaat aaatcgtgga cgcatatctg gtcgcccaca
    17221 gcccgattca accaaactac ggccaaccgc atattacaac ggaatcccac cacaagctcg
    17281 tctgccatat ggactacatt cgccacctat cgcctagcaa ggcaacggat gttatctacc
    17341 caactaagtt acgaggcgac aaagaatgat acttcgggcg gaaaggcatc cacatggcaa
    17401 atgactgtcg gatggaatcg tttggaaaat gatttctaca tatatccttt tacggtcaaa
    17461 caatatacag ggctcttcca cggagagatt gcgttttttc gacaaatccg cctacctaaa
    17521 gaaaacaagc taagtatccg cccgtccgtg tatatcgtat cgggctatgg taccgagatc
    17581 aaatgggaga aggaaacgca gaaggatgag aatggctcag cagaaatcaa gctagagcag
    17641 aacatgcaaa aagtgaacga ggattttatt gctcgcacgg caacccgtct gggtatcggt
    17701 acggaaatgg aatatcggca tcccattcat tccgccttat cagcgggatt tcgtttaaag
    17761 ggtagtctcg aacaaacgac aagtcctcaa tcgaccctcg gagggggtgg aaacttcagt
    17821 attgtcatct ggctataaat aggtctaata ctatgcgtta ctcaactttg tacaaaatac
    17881 caataaggat cgtgacgata tttctcttat tatcatcact tcatccgggc aattaccttc
    17941 acgggcaaga gcaaccggat actctgtcct tctatttacc caacattttg gtaacagcca
    18001 tcgagtctaa gactccgggt acggtttcct tgcttcctgc atcaacattg gaacacacgc
    18061 aaccgatcac gatcgctgat ctgacacagt tattaccagg aggtctcacc aataattctg
    18121 gggtgacaga cgcacaatat ttctcagtgc gggaggtttc tttaaagaac ggggtaaacc
    18181 aatttcataa aaacgcagct atgggtgccc aaatatgggt agacggctct cctcttcatt
    18241 tcaacaccgg catcaacgag ccttacgaag gatatgatgc ccgttttcta tctctcaacc
    18301 aagtgaaaga ggcggaaatc atccggggaa taccttctgc ccggtacgga aacttaacaa
    18361 atagcgtatt attactcaag actcatcaag gtagaatgcc tctctccacc agcatacgtt
    18421 acaatccgaa actgaaacaa tatatgcttg gaaaaggctt ctgtatctcc ccacaaggcc
    18481 atacgctcaa cctgttagcg gactatacca gccaaggcga tttccatacc ggcggcatac
    18541 gcttggcaaa cctttaccat tggttgcccg cagggaaaaa actagaatta agccttactt
    18601 acacctctcg cataggaaag gaaaagcaat tcgtcaacga gcagaatcat acacaaagac
    18661 aacgattgga tcagcgattt tccatacaag gggaatggca acccgaccga cgttggctca
    18721 agaagctgtc tctgagaata gacggttccc ttcaaaaaag caaacaaaca aagagtcagg
    18781 tcaacaatgc ctctagccag ctttatacag accagaaaga gagcggcgaa tgggaagccc
    18841 atgttttatc ctcaaactac atgtacacat tagtcaatga aagccgacct ttttatgtag
    18901 aaaccgagat gctggcgtct acctcatttc cgctacggca gagacgtgaa atcagcttag
    18961 ccgccggatt ctcatggcgt ggtgagggca acgaagggcg aggcagggat ttcgatcggc
    19021 aaaggcctcc ttctacatct atccgtcccc gctcattccg ggaaatccca tccttgcata
    19081 cgttcggtgg cttcattgag gccacatacc ggactcccaa cctccatgta gaagccggat
    19141 taagaaatca aggattgaaa agccgggatt atgccttaat ctatcagaca gaacctcgcc
    19201 tgaatctctt atggtctctc tgctcctctc cctccggcta tacattgagt ttaaaagccg
    19261 gggtcggatg gatcagtttc atgccgacat tggaaaaact ctacccggaa gctatttata
    19321 atgataaggt ctctttctat tataatgata gcaatgaaag tggaaacacc cttggtattc
    19381 tcacgacaca tgcccccgga atggaacgaa atatgaaatt aaaacctacc gtaaatcgaa
    19441 agatagaggt tggccttata gggaagactc cggccatccg actagacatg accgtttttt
    19501 tcgagaaaca aacggatggc ttttcctcct cggcgcaata tattccgttc agctatcggg
    19561 aatatgatta tctatcaacc gcccaacttc gtcctgaata caaagatgga caggtatggg
    19621 tgaacggtaa ggctgtccct tatcaagaga aatatagtta cacgccggta tctgtaccag
    19681 tcaatacact ccataggaag aaacatggga ttgagatggt agcggacctc gggactttct
    19741 cacccttgcg tacctcccta atcgtagacg ggatttggtt atatgtacga gaaaagaata
    19801 cggcccttaa cgggatctgg ccgatccagt acacagataa aacagaatac ccctacgtag
    19861 gtttttacga caggcaaggc ggaccgggaa atgaaagtcg ttcggagatc atctccacga
    19921 acttccgttt catcacccgc atccccagaa tcggactggt cactaccctt acgtggcaaa
    19981 tgatatggct ctataaatat cgtacgctct acaacggtag cactggcgag aatgtatggc
    20041 ccctatattg gtgtggaaca gacggaatca tacatccgtt caccgaggca cagaaagagg
    20101 atccagcctt tgcgccttta ctctccacca ccgcaccgga acgattccta ccaaactctt
    20161 ataaaccata tggtatgctg aatattcggg taaacaaagc tttcggagag cacatcacgc
    20221 tggcattctt tgccaacaac ctcgccgatt tacgccccac tcgctattca gccagcacga
    20281 gatcttacct tcaacaaaat acccagcctt ttttcggtct ggaattacaa ataaaactat
    20341 gacatcatga aaacaagcat actttacata ttcctactgt cagtccttta cgcctgcgac
    20401 tcccactctc ttcttccacc caagcagcaa ttggatcagc aaatagcgca actgaatgat
    20461 tattctttgt tgagcggtcg cttgaacgac cagctatgcg aagagataga aacccatgcc
    20521 caagaaatag ggaatgactc gcttttgctg gcaacccgcc aaatcatata cactcgctat
    20581 tgcagattac aggacacggc tcatgcgaga atgctactcg accgcatgaa accttatgcc
    20641 atccgcataa aagacaagca ccttctcatg aatcacctgc gtatggcatt tcttcacgca
    20701 cagacacgcc aacccgcaga atgcgagcga tggataaacg aggcacgaaa atatgcatat
    20761 ataaatcctc aaaactggta tatcacggcg gctaacgctt gtcttgaatg tggattatat
    20821 ccccaagcac tcatctatgc ggattcagca ttggtgaact tgaaatataa agtgataagc
    20881 tctcctcact tagtaaaagc tatagcatta agccgtacgg gaaagaccgc cgaagcggag
    20941 gaatggacca aacgatgcat taccgatatc cgccactttc aggcgaaaca ccaaatacac
    21001 acgatcagct atctgcaata tcaactcttc atggaatacg ccgtctctct ccggaaacat
    21061 ggaaaaaaca aagaggcact atccgtattg gaggaattag acagagtctc attcaataat
    21121 gtcgccacgc ctctcttgag gaacaaagac aatatcgagg aatataaggt gcgtgtggca
    21181 cgtatgttgt ccgaatgcta ttatacgacc ggaaatcaat cggaagccat ccaacaggca
    21241 aaccgggctg actccctaca atcccattat gcccaagagc aaatgaacat acgcagaaag
    21301 atgatcagcg aaagcctaca aaacgaacta ttatccaccc gcttaaaaag tcagaaggtg
    21361 gaggcggaac aggcacggct catccagtat atcctaaccg gaatcattat tttactcatg
    21421 gctatcctaa ccggaggata tctttggtgg agaaatcatc gccgtagcct acgccagtta
    21481 ttcgatttat tgataagcca tcatgcagct tggttgctaa tacacgatcc acttccgcta
    21541 atctcccggc cacaaataaa gttaccagat cattcagagg caaacaccga ggtcgcaaca
    21601 aaagctgata atctcctata tcaacgaatc ctatcagtta tgaaagagca aaagcctttc
    21661 ttaaatccta atctcgacct tgtgaccctc tcccgtctag tgggtactaa ccgaacacaa
    21721 ctatccacca ccctcaatag gcagacggga atgaacttta gccgttggct ggctgaatac
    21781 agggtacacc acctcctctc gctcgtcacc ctacaccccg acagtgacat caccgcactg
    21841 gcctccgaat caggcttcac ctcccgaacc tccttcttcc ggcagttccg gcaagtcacc
    21901 ggacttacgc ccaaccaata cagaaacgta cgaaaagaga ccgacaaata atctgttaaa
    21961 gtacgtgtct agcctttgat gcaggggctt tacggccctt ggtgtaccag atcgttcgga
    22021 tcaagtttca atacgttcgc atcttttccc ttcctttggt ataccaaatg ggactgtcta
    22081 tatttgatct cgcaaatccc ttttatgcgg gtcactcaag atagtaccaa tatggaagaa
    22141 aagcaaaagc catccctaat cgaacgcagg ctatatgccc gcatcttaca aatcatggag
    22201 gataagaagc cttatctcga tccacagttc aatttgtgcc agttggccaa cctcgcttgc
    22261 acgaaccgta cccggctatc ctccaccttg aacaatcaga cgggtatgaa cttcagtcgc
    22321 tggctagcca actatcgggt aaagcatctt atacgggagt tctccaaatg cctcacacaa
    22381 gaacctaagg agctatacaa gaaggcaggt tttacctccc gtacctcttt ttatcgccag
    22441 tttaaggagg tgacgggtaa tacccccatt gagtactttg ccaacctata ttacgacaat
    22501 gtaaatcatt caactaaata agtagcgata tgagacatct tacacttcta ctcttatccg
    22561 tttttactgt ccatcaagcc aaggcggata tattgatccc cttagacaaa tatcctacgg
    22621 gggaaaaacg tttcaactta cagatcaacg gaagtcacga taccagtacc ccttggctct
    22681 ccaccacgtc atttggcgtg gatgaagatg ggcagatggg aaacccggag aattggacat
    22741 ccgaacaaat cgacgaggac aatcagtcgg taagtcaccg actcattatg aacagtattt
    22801 ccctgcgtct ctcctaccgt atatgggata atctcagcct atgggcaggt attggcacca
    22861 ccaacttcac ccacgaggag actttccgag atgatgacga cctaagcagt accatcttca
    22921 gcaagaacat ggtacccatc tacagcggag ggctaggtta cggccatgcc ttcaccgacc
    22981 gctttttcat gtctacccaa cccggcgtgc gctatgccaa cagcgataac atgaccaccg
    23041 aggtgtatta ccaaggcaag accatcccct tgcgagacct cagcctcaac cgccgttacc
    23101 tagagtgggc cgtgcccgtg gtggccggat acgcactggg gaatttcgtg ccctatgccg
    23161 gcatcctcta caaggactac acgatgaaag accggtacga gttcaccaag acatatgccg
    23221 gcgaggacta taccgttcgt atcgacgaga ctttccacgc ccgtcacaag ctgtacgctt
    23281 tggctggggt gaactatttc ctcgctgaca acatctcgct cggagtaaac ggaagcttcg
    23341 gcaacaggca gtccgtacag ttacaattca atatcagttt ctaaacctct taaacagata
    23401 tatacatgag aacgacactc aaagcacaag cgatacggct gatcgccata tttttgctta
    23461 tctgtgcctc taccaccatc gtcaaggcac agatcagcca acatcccgaa ctgtataagg
    23521 tgaaagaatt ccacaatatg gataaagacg gaggtgccta ttactgcttc accgacgcac
    23581 aatactacca agggaagctc tacggggtct acatagataa taacggcccc tcatccatac
    23641 gcctcatcgc tttcgaggtg aacggcgaga cccggacaat ggaacaatcc accgttggcg
    23701 acaccggtaa gaaaatgatc tttctcaatg atttcggcgt ataccaagat gccgagatca
    23761 tcgtataccg caatcgcttc tacgtgctct ggaagaataa taccaatggc cagatatgga
    23821 tcggcgaggt ggatatgaaa aagggagaat acaagaaaac tcgtatgctc gatgacggga
    23881 aaacttacgc caacttcgcc gccaccatct accgtgacaa gatctgcgtc atcctacacc
    23941 gccgcaccaa caagaaactg caagtctacc aatacggcga ccccgagctg aacagcggct
    24001 gggactggtg cggcaccgtg cgcaacgccg gacacgataa tatcgagcta aaaggctcaa
    24061 caggcatatc aatggaatac gatcccgacg accactggga cgccacctcg tggtacggct
    24121 acgacgacac cgagaaaaag aacgtggaga aactcatcgt aggccgactc aagagcggta
    24181 ccttcgaggc attcagctac agcggcgaat atggcaagga taacacatgg ccctccaact
    24241 gggaagaata cgcacatcac gacataggcc gctcgaagac cttctcactc aagctcatcc
    24301 aagccgacat cgaaggctat gcggccgaca atactgatgg ctacaaagct tcctcaaatc
    24361 ccctaatctt cagctactgt tcctatgatg gcaaagggac gggtgaacac ttcctaaaga
    24421 aattctaccc cggcagcaac agcttcgccg ccgacgcacc catctacacc gacctgccct
    24481 acggctacac ggccgtagcc accgcagcag atcctaccac tgagacagct cccggcggag
    24541 gactctacta caagcaatat atctatctac tacggggtaa ccagcaacca taccactggt
    24601 tcaagcactc ctacgtcgcc tccatccgat ctaacgagat cgtggagaga cgcagttctt
    24661 tcaacgacga gaaggcctta ttcggcaaca gcgagttacg caatctcgtg cgcctcgtcg
    24721 gcatcatcga aggaccacct ccaacggtag tggataataa cgagtggttc ggcgacctcg
    24781 gcgtagcctc aagccttgcc ttcaccatgg gatcgggcac cagcaactcc gtgagccgac
    24841 tctataaaag cgacctcaaa tgctccttcg ggccgcatac ggacaaactc acggcagcat
    24901 tcggcggcgg atactccttc cagaaacaac acgaggaagt aacaagccag tccgagtcca
    24961 tcaccgttac cttcgaagca aacgacacag cagactaccg ggccatcgcc ctctactctg
    25021 tacccattct gacccgttgc gacctagaat acctctcccc cacccggaga cagagtgtac
    25081 gaatgcccat attcagctat acttacatga cacggcagag tatcaaacaa gtagaagtgc
    25141 ctctcgacct agagcctttc cgcatagaca atccaagcaa acttggagac tgggaggccc
    25201 gtgagatcct caccatgacc gccagcgagc caaatgtcag caagtccgtc aacttcagcc
    25261 tcaactccga acggatcgac atgacgctgg aaaccagcgg cacaatctcc gacagtcaga
    25321 ccaaaggtgc catcagcctt atggatttga aattcccctt cttccaactg gagaaccaaa
    25381 gttcttggga atggacagac cagaccacgg cgacaacctc gcagggtatc agcgcatcct
    25441 attcgaagat acgacgcacg gacaagcacg tcaggccgga agagacagcc gagtccttct
    25501 catccaccct ctatctgctc actgccgaga agtcgaacac gctccgtgac cagtactacc
    25561 ccaagctact cgaacggaag atcagcttcg gcaccgacac ctttcccttc atggtaaaca
    25621 gcgacaaacc cttcgtattg gcgtgggaca tcaacaacat cacctatgta cgaggtgacg
    25681 tgagcgccac tggcaatgag gaggtaacga ccgacgagcc cctgtctatc cgcttcctcg
    25741 acggcatgct tacggtagat tgcctgccgg gagccaccgt caacgtctac agcatgaacg
    25801 gcacgttaac cggtcaccag caagcggtat ccggaaaagc aatcttcagc ctgcccggac
    25861 acctgtacac cgtggaggtc gtgaccgaac gttaccggaa agtacagaaa gtagtgagat
    25921 aatacagtta gaagccatga agacaaacct cctccagaga aaacgcctcc taacggaaga
    25981 atcgaatcgc tgttatctgt gcgatgaccc tgtctgcacg aaggcatgca agcccggact
    26041 agatccgggc cgcttgctgc gggcctgtaa aatggacaac ctagcgggag ctatccttcg
    26101 ggcctaccgg atggaagcct gcaaggattg cgacgggcat ccttgcgaga aggcctgcct
    26161 ccgcggacga accgaccggg cgatatccat cacccagatc gtacggcaat tacaagatat
    26221 gccaaacccg acggatagtt ctcccctcac ttcgtctccg gacttggcga tcgacttttg
    26281 tggtgtccgc tgcgccaacc cctttatact ggcctcctca cccgtagccc ataattacga
    26341 gatgtgcgtc cgggccctcg aagccggttg ggccggtatc tgcttcaaga cgatatcatt
    26401 ctatccgagc catgaggtat ccccccgctt cgaccaaatg gaggtggatg gcgtgccttt
    26461 catcggattc aagaacatgg aacaattgtc ggaagcctct gtcgaagaga atttcgatac
    26521 tctctatcgc ctcaagcaac gctatcctga caaattaatc atctcctcca ttatgggacg
    26581 gacagacgat gagtggacac ggcttgccca atattccatg caggctgggg ccgatatcat
    26641 tgagtgcaac ttctcttgcc cacaaatgac gcaagaaggg atgggcagcg acgtaggaca
    26701 aagcccggaa ctggtacgcc ggttcaccgc cgccacacgc cggggtaccc atctgccgat
    26761 actagcgaag atgacaccga atatcgggca gatgacaccc gtggcgctcg ccgcccacga
    26821 aggaggagcc accgggatag ccgccatcaa caccatcaaa tgtatcaccc gtatcgatga
    26881 gaaagcgttt acagcccggc ccgttgtcag cggactgagc agcgtgtccg gctattcggg
    26941 gagagccgtg cgccctatcg ctctccggtt catacacgag ctggcgagcg atccttccgc
    27001 cggcaagatg cctatcagcg ggataggcgg tatagagact tggcgggatg ccctcgattt
    27061 cctgctacta ggctgtacaa acctacagat atgtactgcc gtgatgcaat acggcttccg
    27121 gatcatcgac gatctatgcg aagggttacg actgttcatg caggagaatg gatataaaga
    27181 cttatccgat cttatcggta tagccttacc gaacatcgtc ccccccgaaa gactggaacg
    27241 tacgcaaata caccgcccga cagtagataa cagcctatgc ctcggctgtg gacgctgttt
    27301 cgtttcctgt aacgacggtg gacatcaagc tatccatttc acctctatgc gcaaaccggt
    27361 gatagacgag caaaaatgtg tcggctgcca tctttgcgca ttagtatgcc caaccttcgc
    27421 catacattga caggatgagg atcgagacgg aacaccttat tcttctattc atacttcttc
    27481 tgtgcccgct agtccatcca gacctgcggg cacaagagaa gacacccgtc acgcgagccg
    27541 actccatcat gcgacaggta atccatcaag cccccatcta cgagcacgtc ctcgagagct
    27601 atgaagcgga gacctacgtg aaaggccgta cgcacgttcc ccggaagaac aagctgctac
    27661 gatacgccta tctggtcttc ccgatagagc gtcatccccg caatgccttc ttcgagatga
    27721 gtggcctcac ccgctacgac gctcccaacc attatcgcaa caagatcgta gccatcaaca
    27781 gcagccatct cgccgccgga aggcattaca aggagatagc ctcgttcgtc aacttgaacg
    27841 tctactctcc cacgatctac aataagggaa tgatcatgcc actctcgccc gatgctttca
    27901 aatattacac gtttcggcag gaaggcacgg acacgatctc cggcaccctt gtgtataaca
    27961 tccgtttcac ccctcgccaa tggagccaga aactactatc cggaaacctg tacgtaaccg
    28021 acgaactctg gaccatcgac cgtatcgaga tacaagggca ctcctctttc tccgagttca
    28081 acctaagcat acgtttcaac cgtgacgaga agcatttcat cctcccggaa gaggctgacc
    28141 tgcaagtctg ctaccatgcc ctaggcaacc ggatagagag cgacatccac gccgctttcc
    28201 gctataaatc gatctcttgg gtagaggaag accatgagag caggaaatta tactcgctcg
    28261 atcaaaccca atactatacg atcacctccg acacactctc ctttacccaa gacagcactt
    28321 attggaacag ccggagggac aagccgctca ctaccgacga gaaagccttg tacaccaccg
    28381 gaacgaacgt ggtgaggacg gaagcggaca gcagcgctct cactcgctac ctccaactcg
    28441 gcgagcggct caccagcacg gtcaacaggg attacaagag tactcgtgtg aagtattccg
    28501 gccttctcaa cccgttccag ctatctttcg gaagcaacgg gatcacctat aagcaagaag
    28561 cacgtatcag taagacattc gagcatgacc gtcagctacg cttccacccc gagatcggtt
    28621 tcctattcaa ggagaaagag ctacgcctac ggctaacaac cgactgggag tatcaccccg
    28681 agcgtcaagg catcctcaac ctcacgatag ccaatgacaa ccaaagctat tcctccgaag
    28741 tgatccacca gatcaacgag atcctaaaag ataccccaat ccgtttcgaa gatctcaact
    28801 tgaagtattt ccagcactac tatgccaagc tgatgaacca gatagaactg atgaacggct
    28861 tccggctctc ggccggactc gcataccact atcgtacgcc cgtgaaaaag aataaggata
    28921 ccggattgga tctaaaggat cataatgagt tcaccccggt tatcggcctt acctacacgc
    28981 cccggcaata ttactggatg gacggttacc ggaaagagta cctgcattcc cattacccga
    29041 ccttccggat cgagctggca cgaagcatac cggacctgct cggctgtacg ggaaattatt
    29101 ggcggatgga ggccggcatg aaccagaccg tacggctggg cttatccgaa cgactgagtt
    29161 acaatctaag cggtggactc ttttttaacc agcataacat gtacttcgcc gatttcagct
    29221 atttcgccaa acgttatttc cccgagcctt ggggcgaccg gtttggcggg atctttcata
    29281 atctaggtgg ggattggtgc aatgcctccg acaaatatat tcaagggcac ctcatgtacg
    29341 agagcccatt cattctattg cgattcctca agcccaatcc caaggcgcat aaatacctcg
    29401 tgtccgaacg tttctacctc agccagctat ggactcccgt attgccgaat tacagcgagc
    29461 tcgggtatgg tatcggtagc gacctttttc atatagcgct tttcctaggc ttcgagaagt
    29521 tcaagtatca aagcgtcgga ttgaagttcg cgcttgagtt attcagataa ttataaacaa
    29581 gtatagatat gaacaagaga aacactatta aacaacttct tcaccgcgga tgcctactta
    29641 tgggtatcag cgcaataaca agttcggcct tcgcatggga tttcgccgag catcgtaaga
    29701 tcggcgaccg tgccatgagc cttctcccgc gttatctggt ggaaaacggg atcttcccca
    29761 acgaggccgt cgccgatagc gccttgctgc agatcctcaa catgtcgcat atgcccggct
    29821 cgaacgccta cgccatgaat gagctgacgc agttgccgaa tatcgtaacc tacggtacgc
    29881 tttgcggatt ggccggcgac catgtggaaa atcccatgct cttggagaca ggcctgcaga
    29941 cccatttctc caagacgaac cgtacgctgg ctttggagac acaagccatg aacgagttcc
    30001 tcaccggagc caacagcaag gagctgctcg acatcaatct ggcttacggt atcctggcga
    30061 tcaaggacct ctcccacttc tacgcctatg gcaagggatt gaacgagcat ctgaagatga
    30121 tcgaccccga gctgatccgc cgccttcaac gcccctcgga agtaaacaag gtcttcgata
    30181 aattaaatca gttgccctcc atgagcaagt atttctgcat ccacatcttc gccatctatc
    30241 tagcacaaga ggcaggcaaa gaaatgtgta aaggagatac gcaaatggcg agcaacctta
    30301 tgttctacgc cacgatgtac gaggctttcg ccgagcattt cctacaagac tccttcgcct
    30361 ccggacacca aatggtacgt aggggcttct ccgcctccgc cgtatccaac aataagagcc
    30421 tgcacgattt ctacaatacc atccccgtac agaccgctaa cctaaaaggc gagacatgga
    30481 gtgcttacgg cgataaacgt ctgaaccaaa acaggatgga gtacaacgaa gccgatgatt
    30541 accggcatat ccgggtcaca gagaagcacc cttattcttt ggagaaaggc gatagctacg
    30601 agcgggaaac gaaggtattc taccaagtcg tgactgccac ctgcgagtct atcgtagaag
    30661 tctggaaagc ttaccagaat gctttggaag gatcaggcga gaatatcttg aacgagatcc
    30721 cttccgaacg agacgacctg ccccagttcg tctacgatcg tttcccggta atcaaggatt
    30781 tcccgatccc cttcgggacg gatctggatg acgtcccctt gaaagcttcc gtcgccgacc
    30841 gtaaggatga gctacagctg atcgtacaag agccttttac ccgcaacttt atccggtcga
    30901 gggtagccaa ctccttcatg ttcctgatcg gcacgccgat ccatagcaac cgggacggtg
    30961 tcatgacgta tggcggtcgc ttgaacgtca gcatgatcaa ttggcataag ttcgggaaag
    31021 ggaaaggcat gatcatggag ccgggcgaca tcgctcattg ggtatcccct acgatctccg
    31081 gttattatat gcatgcccct tcctcctcct acacgatcaa gaactggaac gtgaaggcgg
    31141 gcgccaatta taacatggat atattcgttt ccccgaaacg tttcctcggc ctgtatagtt
    31201 atttcgagat gggtatagac cgccgtaatg acgagacccg tttcttggta gctccctcgg
    31261 tcggtatcca gctaggttcc ctgatcggtg tccataattt caatatgccg ggatggttac
    31321 gcatcccgtt gggaattatc ctccccttga aattcgccgt cacttgcaat aaggtggccg
    31381 gccgtcccgt agaatggatc agcaatatgg aggtggatat attgttctag gaaacacctt
    31441 gattcatgcc tatacaggta agagaccaca cggatatcgg cgtaacccct tacctgtata
    31501 ggcacagggc cacgccgata ctcgcgtagt gtcatacgta tatacgtgtg atctcatcga
    31561 tttcgccgaa cccgatcaag gcgttaaaca gacggatccg ggtatactta ggcagatcct
    31621 ctaccgggat atccccggcc tgtaccaagc ctttatccaa taagtaagca cgcatcgtac
    31681 cacataacaa agggcgtgcg ggagtgatcc aagaggtgcc attccaaagg gcgacattgc
    31741 aaatggaagt atcggtcagc aaaccgtcac ggatgatcag gatatcgtca tgcccccctc
    31801 gttgggcgaa taaatcattt aagcattgac gatccgtact cttataggaa taatcgatct
    31861 catcgcatgt aaccaatcgc aaggaatgaa ccggacgcat acggtaagga acgtattcta
    31921 cctgtaagac ctcgcaggta tattccaccc ggcatttggt acgttcttga tgaggccccg
    31981 gatgaatata acccgcgaga tcaatttctt ctctcgctcc gaatagctcc ctgcgggtac
    32041 ggttcatacg ggcattatgg tacggaaggt tatgtatccg tcccctctcg atacggatcg
    32101 tctccacaaa cggactccct gataaggtct caatagatgg gcacatatac tttttgtttc
    32161 atctcgttat actccgatct cacatcactt ttagaggtga ttcccccacc gctcttgaaa
    32221 ataaacgaac ggggagagac ttgttccata aaacggatca tcacggcgct gtctaaatct
    32281 tggccgtcaa aataccccat cacccccgta tagaagcccc gctcataggt ctccgcctcg
    32341 gcgatgatct ccaaggtctt tttcttggga gcgcccgtga tggagccggc aggcaagagg
    32401 ctaaacaaaa tctccccgac atgggcgttc cattcctccg gcaaccggcc tcttatctca
    32461 gagctgacct gcaacaaact tccgttatgc gtacgcaatt catcgatata acgataccgg
    32521 ggaacacaaa cctcggaggc tacgatactc aagtcattcc ggatcaagtc cacgatcgtg
    32581 gcatgctccg ctgcttcctt gggatcatcg aggatacgtc tccgggcatc gggcagcgta
    32641 gcgtcgatcg tacctttcat gggatacgaa tagatgagac catcccgcgt ccgcacgaat
    32701 atctccggcg agaataccac gaaacgatcc cgcatccaaa gcttatacat cgccttggat
    32761 tggtagaaga tatcttttaa ggagagattc gcatgtaccg gagtagcgca tgtcaagttc
    32821 accaaataag aattacccgc atggatatgc cgggcaacgg tctcgaacga atgggcatac
    32881 tcctcgaaag aaacatacga gggctgccat tcaacaggtt ctccggatat aagatgagag
    32941 gaatcccgca agttacattc gtgatttgta ttcgtaaagc cgttcaaatc gtacaataac
    33001 tcggagggag cgatctcttc cggactctcc acatagatcc gctctcgttt ataatcaatg
    33061 ataaaaagaa aaggccgtcc cgctttcccc atttcgttca tgcggaagac ggcctcttct
    33121 tgcgtgtatt cggtcattat actaaaaatc gttctgtcaa accaccaaac gcatcgatac
    33181 ggcgatcccg gaagaaaggc caccaacgac gcacgttctc actacgggtc ttgtcgatct
    33241 ctatcacacg tacctcctct tcgtcattcg ggaatacggt taatagctca ccttggggac
    33301 cggccgcgaa actgtttccc caaaaccgga taccgcccgt ttgtcccgaa gggtccggct
    33361 catgcccggt acgatttacg gaaatgaccg ggagtccgtt cgccacggca tgtccccgct
    33421 gtatggtcac ccacgcaccc agctgacggt ccttctcttc ctgcgtatcg ctactttccc
    33481 agccgatagc ggtcggatag atcaacatct cggcaccacg catagccatc aaacgggctg
    33541 cttccggata ccattgatcc cagcaaacca acacaccaag acgccccaca gaggtatcga
    33601 taggctcaaa gcctaaatca ccgggggtaa aatagaattt ctcgtaataa gcggggtcat
    33661 ccgggatatg catcttgcgg tattttccgg cgatcgtacc gtctttctcc aagacgacgg
    33721 ccgtgttatg gtacaggccc ggggcacgct tctcgaaaag ggaaagcacc aagacgatac
    33781 ccaattcttt cgccaaggca ccgaaggttt ccgtcgatgg gccggggatc gtctctgcca
    33841 agtcaaacat actcgtatct tccgtctggc agaaatacag gccgttatgc agttcttgca
    33901 agacgaccaa ttccgctccc tcccgggcag ccttacggat atttaccttt agcttctcta
    33961 tattcgccgc tctgtcagcg gtattctttt gttgtattaa tcctactttc atatttaatt
    34021 ggttgtagtt attattcgat aaagctttcc ggatattgca tcgtcacgca atgcagggaa
    34081 ccgtgttgct tgataagcgg aaggcaattg atacccacaa tctcacggtc cgggaacgct
    34141 tcccgcaaaa ccgctttagc gatctcatct ttcggtgagt catagaacgg aaccaatacg
    34201 gccccattca tgatcaggaa attagcgtag gtagcgggca agcgctcccc ttcccattcc
    34261 accttatcgg ccatcggaag tggaatcaga cgataaggct ccccattcgc cctagtaaac
    34321 tccttgatct cctcctccat cgccttcaat tcctcataat gctcgtcttc ctcatcctcg
    34381 caacggacat aagcgatcgt atcctcgcta cagaaacggg cgagcgtatc cacgtggcta
    34441 tccgtatcgt ctccggctaa ataaccgctg gtaatccaaa ggatacgatc caagccaaat
    34501 acgtctttca aataacgttc caattcctcc tgttgcaaat actcattacg gtttacggat
    34561 gccagacact caacggtagt catcaacgta cctttcccat ccgattcgat actaccgcct
    34621 tccagcacga aaggttgcat attagcgggc accacctcac cggagaaggt cttcatatga
    34681 caaaggttac gggtaatcag attatcatga ttggcggcga acttcattcc ccagccattg
    34741 aacacgaaat cataaagcat gggcgttccc tcatcgaaga cggaaattcc cccgtgatcc
    34801 cgtgcccacg tatcgttcgt atccatctca cggaaaatga cacggtcgta atcaacctca
    34861 cccaattgtt cacgtacggc ggtctcgtcc ggacagacaa tcaataactt ctctcgcttg
    34921 atcacttcct tggcgatagc cacgaagcaa ggaatcacct cgtccaatat cggggcccaa
    34981 tccgtattct catgcggcca cgtaagctgc acggcacttt gcggatacca ttccgcaggt
    35041 aatatcacgt tatgttccat atttgaattg tttaaattgt ttcacaagca cgatcgccgt
    35101 cacgatcgcc gccaccgtat cggcgatagg catactgatc cagacaccga gagttccgaa
    35161 taacgggggg aggaggatta aacagggtat caagaaaagc atctgccggg tcaaggagag
    35221 aaagatcgct ttcttagaca tgccgatgga aaggaagaag ttagtcgcca ccatctggaa
    35281 gcccacgatc gggaatacgg cgaagacgat atgcaggcca taagaggcgg cactgatcaa
    35341 ctccccgtca ctcgtaaaca tacggacgat ccacgacggc accaactggc aaagcaagaa
    35401 ccccagcgta gccactccta ccgcccagcg catcgtcagc cgggtcacgt ccgtcacccg
    35461 ggaatagagt cgggcaccat aattataacc ggctatcggt tgcataccct gattaaatcc
    35521 catgatgatc atcacgaaaa gaaaagcgat acggttcacg ataccataag cgccaatcgc
    35581 catatctccc ccatgctctt tcaatccccg gttgataagg atcacgatca agcaggaaca
    35641 aaggttcatc aagaacggag ataaaccgat cgacaagata cctttcacga tctccgagtg
    35701 cagcctataa atacctttct tgaaatgaag gagttgcttt ggtcccgaga aatgaatcaa
    35761 ctgcccggta agcgagatca cctgcgagat caccgtcgcc caagccgacc ctttgatacc
    35821 ccatccaaac ccaaagataa acaacggatt caaggcgcaa ttgataacga ccgacgctaa
    35881 cgtagcatac atcgccatct tcgggaaccc agaggagcgc aagaccgcgt ttaatcccag
    35941 atacatatgc gtaaccacat tgccatacag aataatccgc atataatcac gggcatatga
    36001 gatcgtgttc tcactagcac cgaaaaagta cagcacggga tcaagcaaga acaagaaagc
    36061 gatcgtgaaa gcgacgccca aaaccacatt caagatcaac acattcccca acaccttatt
    36121 cgccccctca taatctttct gtcccagctt cacggcaacc aacgtagagg cgccgactcc
    36181 caccaacgaa ccgaaggcgg ccgccaagtt catcaacgga aaggtcaagg ctaggccgga
    36241 aatcgctaac gcccccactc catggccaat aaaaatgcta tcggccatat tatataaaga
    36301 agaagctgtc attgcgataa tcgcaggaat cgcatattgc gtaagtaatt taccgatagg
    36361 ctcggtccct aataccaatg gagaattttg ttttgtcatg ccgcgaagat acggatattt
    36421 cgatttattc tttatattcg cgaccttata atagtttaaa tatggcagag gaactacgga
    36481 ttaaaaatgg tgataaacag gaaatgtatg agacgttgct cccgcaaatc gcctcattgg
    36541 taggtaacga gaccgaccta atcgctaaca tggcgaacgt cgccgcagca ctcaagcaaa
    36601 ctttcggttt cttttgggtg ggtttctacc gggtcataga caatcagttg gtattagcgc
    36661 cttttcaagg ccctatcgcc tgtacacgaa tcaaatacgg aaagggggta tgcggcacgg
    36721 cttggaagga gacccgtacg atcatcgtac cggatgtaga cgctttcccg ggacatatcg
    36781 cttgtagctc ggcgtcacgc tctgagatcg tagttcccgt gatatgggag gataaggtaa
    36841 tcgctgtcct tgatatagac agtgatcaac cggatagttt cgatgagact gatcagatct
    36901 ttttggaaaa gatagtggaa ttgcttcctc atcagtaagc ctcgcctcag tacttcccaa
    36961 gaagtactgt agtactgcct aagaggtact gcagtacttt gtaaggagta ctccagtact
    37021 ctccgaagaa ataccacagt acttcgcaag gagtactccg gtactctccc tgaagtaccg
    37081 ggacaaatgc tacttaccgc aaataccctt aaatggacaa taagaacaag ccttccccgt
    37141 aggggtttgc gtaaagggaa tttccggatt gaagatctcg tccaagcagc cccgcagccc
    37201 ctcctcgaac gcttgggcat aaccggagaa atcctctacc ttctccgact tcccccgttc
    37261 gatacggtgg tagaccgatg ggtcgaacgg atcggcgaaa agggaacgga cgtaataaat
    37321 gcccggttgt atcgtctttc ctttgttctc ggtgagatgg gcgtacatcc agcaatacat
    37381 aaatacctgc atcacggctt tcgcacgatc tttctcctcc ttgttgaata ggctctcgat
    37441 actactgaaa gtcgtagttc cgctaccgct cttgtaatcg atgatacgga tagcgtcgcg
    37501 aacctcgtcc acacggtcga taaagccttt caaccggatc tcggaatagt cggaaaggct
    37561 gatcagaccg tttatcttac gctcggactc gatgtaaacg aaaggggtca gcttgccgtc
    37621 acgctccaag attttctcca cgtatttgcg gatcatctcg ccgatcaggt agttttgtcc
    37681 ggtaagggag cgaaccacct ctgtcttgaa aaactcgctg gcgaaagccc gggcgatagc
    37741 tccggtaagc aaggccgtat ccttacggat cgctttcagc aaatccacgg taaccatctt
    37801 cccttggaac ggcttgtaaa gctcctccat cactttatgt aagatacttc cgaatacatc
    37861 gctctcgatc gtctcgctca cctcctcttc ctctcgaatg ccttccacga cggaaaaata
    37921 gaatttcaac gggcaatcca gatacgtatt gatagcgctc gccgagatcg ccttgctccc
    37981 ccctttccgg taagcgtcta aacggcgcat gatatcctcc cttttcggca cggccaatgg
    38041 cggggtcttg gaggaagata cgttatagac caccaattta tctcgcatcg gcacctcgta
    38101 atgataatgc agctggtgga caaagcgact tacctctccc gtctgcaatc cgttgctgcg
    38161 ggtatcgtat aaaaggctca cgtggctggc acgctctatc aaacgataga aatggtaggc
    38221 ccatacgcta tcttgatgct cgtaggtagg caacccgaaa cccctgcgta ggttataagg
    38281 gataaaggag ttcgccgctt tccgctgcgg gaaaataccc tcgttcatgg ataagataat
    38341 cagacggtcg aaatccaagg cacgggtctc gagcacaccc ataatctgga ggccggaaag
    38401 cggctcgccg tggaagggga tcgtgatcgt atcagtcacc cgcttcaata ggcggaagaa
    38461 ggtatctatt ttcatctcta tacgagcgtc tttcattacc tctttcatgc ggtttaccgt
    38521 ggtgaaataa tggaagatga actcttgctc caaatcgttc gtccgctggg gtgcgtcctc
    38581 ctcttcctca tcggaaaggg cggacataac cttgttcagc tcttccaaca ccttgatcag
    38641 atagtccgag aaggcctcca ccccggtcac cggcgtgaac aggatttcta gcaaaggcgt
    38701 tttccctaac tccgtatgcg agatatagat cttgttgttc tccgtgatct ctttcaccaa
    38761 ggaggaaata atctccggtg aggtggagag gatgtagcga tggttcaata ccggcagcac
    38821 gtcgcggaaa tagaacaacg gattccggtc tatgtagcgt acgttcttct gcaacgccaa
    38881 gatatactcg atcaacgagg cgaccggggt tcccgccaag ggataaccca tcgtgacgtt
    38941 gatacgccgg atttgctccg gtatggcgtt cagcaccggg atcagcagat gttcatcggg
    39001 caagatcacc gccgtacgca gggcttcttc cgaactcatc tccgcttcct tgcaccaatc
    39061 gctcaacagg gtgtagacgt gcttggcctg cccgataccg gaagggatgc cgatcacctc
    39121 gatctcggtc tttaccttct cctcgggggg taatttcatc gaggaaggga agctcttccg
    39181 gttacgggag acgaaataag aggccttatt atccggatcg gttaccttat cggatacata
    39241 atcccaatag aaatccgcta tcttccgctt ctgcaactgg gctaagaaac gttcttccga
    39301 tacggacaag gcgttcaaac cgacaaagac aatttgctcg taaggtaaat ccggagactc
    39361 gcaccgttcc atgctttcca cgacctcccg gaagatcatg ccctcgtagc cttttccctc
    39421 ggcggccaag gtcgcacgga attcctcata gagatcgtat agcacttgcc agaccgccaa
    39481 gaactgttgc tggttcggcg tatcgccccg gggataaaaa ctggaccaga aactacggat
    39541 agcggcgatc tgctcatcac ttaagaaatc gaaatcattc tctatctccc gtaggtccgt
    39601 cacgttactg aatagcatgc gggcatttgc catgtactta tcgatatcgt cgaagtcgtt
    39661 gagcaacatc tcgccccaat acaggaattc atcgaaagtc tcggtggaac cgctttggcg
    39721 gatgtagatg tcgtacaggg taaaaagcat actgatccgg tcggcggatt gttttccgct
    39781 caactggata aagagatcgt tgatcgtaag gattgtcgga gagaaaaggg gaatatcggc
    39841 tacctccgag agatatttct ggaagaaaag tcccgtacgc cggtttggga aaacaaaggc
    39901 caaacgactg acctccgctc cccatttctc gtaaaaaaga gacgctactt gatataagaa
    39961 cggtttcatt tattctaaaa tttgtacagg ctgcggagac ggggcacgcc ccgtctctac
    40021 aatcggatac gattcacgtt atattaagat gttctctatc tcctgcaatt cttccccgga
    40081 gaaagagata ttatctaacg ctttcaggtt atccatcaat tgggcgacag agctagcgcc
    40141 aattaatacg ctagttaccc gttcgtcctt taataaccaa gcgagcgcca tctccgccaa
    40201 ggtctgtcca cggcgggcag ctacctcatt tagcttacgg gccttttcca cggcctccgg
    40261 ggtaacttga gaggtctgca aatgaccggt cgatttcgcc gcacgggaat tctccgggat
    40321 tccacgcaaa tacttatccg taagcaagcc ttgcgccaac ggcgaaaacg ctatcatacc
    40381 cacaccctct tccttcaata caggcaataa atccggctcc gtccaacgat cgaacatcga
    40441 atagcgggct tggtgaatca agcaaggcac cttatgctct ttcagtacgg ccaaagcctt
    40501 acgggtctgg ttcgcatcat aattggagat acctacatac aaagcctttc cttgccggac
    40561 aatatcggcc aaggccccca tcgtctcctc gatcggagtc tccgggtccg gacgatggga
    40621 gtaaaagata tccacatatt ccagtcccat ccgtttcaag ctctgatcca agctagccat
    40681 taaatattta cggcttcccc agttcccata cggtcccggc cacatatcgt agcccgcctt
    40741 cgtagagata atcatctcat cccgataagc gcccaagccc ttcttcaata tccggccaaa
    40801 attctcctcc gccgatccgt aggccgggcc ataattattc gccaagtcga aatgagtcac
    40861 gccatgatcg aatgcggcgt gagcgatctg gataaaatta ccgaacacgt ccacactacc
    40921 aaagttgtgc cacaatccca aggaaacggc cggcaataag ataccgctcc gtccgcaccg
    40981 ccgatatatc atatccgcat agcgattctc ttccgctttg taaaactcca tatgctcttt
    41041 ctttttttaa ttattatatc tcatccggcc aaggaaccgg tttacctgtc gccttaaacg
    41101 acggacgttg cccgtccact ttccgtaaat acgtacccaa ctccccggac agacgcttta
    41161 cgatatcggg atgctgcctt gccacgtcat tatgttcccc tatatcctcc gggatattaa
    41221 acaattcctt cctccccgtc tcgtaataat agatcagttt ccagtctcca ttacgaaccg
    41281 agcaagtcgg accgattccc ggcccgtcat taccccatat attcgggcag ttccagaata
    41341 agctacgtcc cacggaagga tctcccgtac cttttaataa aggcatgaaa ctgacgccat
    41401 ctatcggctg tacggtctta taccccctta tgcctgccat ctccaagata gttggataga
    41461 aatcctctat aatcaagtat ttatcacatt tgcttcccgg cttcaccacc cccggccaac
    41521 gcacgatcat aggctcacgg actcctccct cataggcgga gcctttacca ctgttcaagg
    41581 gatagttttg cgtatggatc tctccgtcac gccatccggg ctcgctggaa agaccgccgt
    41641 tatcgctcat gaagatcacg atcgtgttat ccgcctcgcc attcttctcc aaccagtcca
    41701 tcaaatcgcc cagactctta tccattccct ctatcaaggc agcgtaagcc gcctctttag
    41761 ccgttaaccc cttatcgata tatttctggt agaaacgctt gtccttatca atcgggatat
    41821 ggatcgcata atgtgacata tataggtaga acggctggtt atatttctta gccttgtcca
    41881 acgccttgat cgcctcctgc gtcaaggcct ccgtagcgaa ggtgtcgctt ccccaatact
    41941 tttccaatcc ggggatagcg ttcggagcgt aaggtttacc atccttggta tgcccgtaat
    42001 tattctcgcc gaggtaactg gcgagacctc cggcggcatg cccggctata ttgacctcga
    42061 atccccaatg atgcgggttc tcccccgggg tatcgatcgc cccaaagtgc gccttgccgc
    42121 aatggatcgt atgatatccg ttattcttca atatctgcac gaatgaagta cccacaaacg
    42181 tattattcgt cccgctcact tgagccacgc cgttataatt ccaatccggc agggtaagca
    42241 catcactctc ccggtcagtc gtcttatcct taaaaagtgt ccagttcgta acccggtgac
    42301 gggcggcatt cgtccccgtg atcaagctgc aacgggtagg cgagctgata ctgctagcgt
    42361 aggcttgggt aaacatcatg ccccctttcg ccaatcgctc catgttcggg gtctcatata
    42421 cctcattata atgcgtcttt tggatccaaa aaggtaagga cgtatcctcc catcccatat
    42481 catcaaccaa gaacaggatg atattcgggg gacgactggc actctgggcg ttcgctaccg
    42541 ccgataccga caataaagcg atggggataa gctgagtctt cttcatgatt ggcaacggat
    42601 atttgtattc tacgaaagta gatatatttc accgaaaaac aatattgttt catatacaaa
    42661 ataatattgt cttatgtatt atacttttcc ggacataaaa taagggaccc ttgacaaaaa
    42721 gagtccctta cctaatatct tttacccaat gatttatctg gaaagcctta acgcaaacga
    42781 tccaaagaac gtaccagcgc ctcatcggcc ccgatattac ggatcgccag ataatccaag
    42841 atcagattga ccaacgggaa ggaaagagcg atcttaacac ttacgctggc accttccata
    42901 tcccccttca aggaatagat caagaaggcg aagaaaccat aaaagcccaa tatcagcaat
    42961 gcgttgaata cgcaaagacg gatttgcagg attcttttcc tatataagaa gatcgtcacc
    43021 aaggcaatga tagcgatgat agcggtcaag gcaaataagc cccacgccgg gtatagtaat
    43081 tccggctcac cgatcatcgt gctcaacccg ctagcatcga acgagaagag agcgtctcct
    43141 tgttgcaaca cggccaacgg caagaataag gtagcgaccg taagcaccac gataattagc
    43201 aggtaaacag tttgtattct ttgtaacatg gtaattagtt cgttttaaat ggaaaggccg
    43261 actcatttga gggtcagcct ttccgatgtt caaaaatatt tcttcttaga agttattctt
    43321 ctctttagca ggattcttgt aataaacctt gccatcctca tactcttgag cggcgatcaa
    43381 cgttgatttc ggaagtttct catagtagcg tgaaatctcg atctgctcac ggttttcaaa
    43441 gacttcctcc aagttgtcat tgtaagaagc gaactcttga agtttctttt ccagatcttg
    43501 tttcatctca acactaatct gattcgcccg ttttgaaatg atagcgactg tctcatatac
    43561 gttacccgtt tcttcactta acttcatcat gtcacgggtt accgtattgg taggagcgtt
    43621 tgattttctg taatccattt tcgttttatt gattaaattc gcttaatatg catctgtaat
    43681 tcgcttgctg gcatagtcgt agaacttcgt tacctgcttt acgtagttac cttccggata
    43741 ctcgttcatg tagttgtaat actcgtcaac cacatcccgg taacggccct gcaacttctc
    43801 ctctacggat actagcgcca actcgtactt cgcacggatg ataaggaaca tgaattcctc
    43861 acgatacttg gaatacgggt aattcttcaa ggcgttctgc gccgtgatca cgcaagactg
    43921 gaagttattc cccatatagg tacctagatt gaaatacaag cgggtggcca tcaattcctt
    43981 gtaagccaac ttctcctgaa gctcgaacat gatgttctgc gcttcctcgg cccgttcact
    44041 ttgcggataa tactccaaat aaagttgcaa ctgctcgatc gccttatacg tctgcgactg
    44101 gtctaaccgg ggatccggag agtccagata caaaccataa ccggaataga aacgggataa
    44161 ttccgtaaac tcccctttcg gataggtcgt ataataggtc tcgaagtatt gcgaagccgt
    44221 ctgataatct ttctgaccgt aatagctttg cgccaacaag tacaaggact cctcggcata
    44281 agctgttcct ttaaagattg taaccagttc atccagcaga gtagcggatt tcgagtattg
    44341 cttcgcgttg aagtatttct tcgcgtacga atatttcaat tcgtaatccg tgctcttcag
    44401 tatcttatta tactctccac aagaggataa tagtactgtc atcatcatca gtaaaaatac
    44461 aacctttttc attcacatac ttttagcgtg caaaattagt gcttttaggc gaataaatga
    44521 aacccaaaac gttaatattt acaacttata taaatcgcta gcagcgatca attccaattt
    44581 attcgctttc aaaacctccg cgcacttatt gacatcgtcc ggacggatga tcacgttagc
    44641 agcgtcgcct tgagaaaaag cgtacatata ttcaatgaag atcccggccg aggtaatgat
    44701 atccatcgcc tttgccaagg ctcccggctg gttgggacaa tgcaagcata ccacgtcggc
    44761 cacgcttaca gcgtataact tttcacgaag cacggatatc gctttctccg tatcggatac
    44821 gattaggcga aggataccga aatcggaatt ctcggctacc gtgaaagcgg acatattgac
    44881 ccctgcctcc cctaatatct tggcgacttc cgtaaaacgg cctttcttgt tttccagaaa
    44941 gattgataat tgttttatta acatagtact taatctttta gaggttatac taacttacgt
    45001 ttatcgatca cgtgttttgc cttacccata ctacgttcga tactacgcgg ctccacgatc
    45061 ttgatgtccg gttgcaaacc gatcacgctc tgcatgcggg cagcgatctt ctttttcaag
    45121 gcgatcatct tgttcatctc gtccgagtag tattcttggc gaacctccac ctgtatctgg
    45181 aaggtatcgg tattgttcat acgatccacc acgatcaggt aatgcgcctc aaactccggc
    45241 agctccaaaa ttacggattc tacctgagac gggaaaacat ttacgccacg aataatcaac
    45301 atatcgtcac ttctacctaa aatacgtccc atacgaaccg ccgtacgtcc acaggcgcac
    45361 ttctcgtaag tcagcgaggt caaatcacgt gtacggtaac gaagcatcgg cataccctcc
    45421 ttcgtaagcg tggtgaagac caactctcct acttgtcccg gttccaccgg ttgtaaggta
    45481 ttcgggtcca cgatctccgg gaagaaatgg tcttcccaca ggtgggtacc gttctggcac
    45541 tcacactcgc caccaacgcc cggcccgcag atttccgtca agccatagat atcgtaagct
    45601 ttgatattta gttttgtctc taattcctta cgcatattct ccgtccaagg ctcggcaccg
    45661 aacgctccga cacgtagctg gaattcctcc aagggaatac cggactggtg gatggtctcc
    45721 gccagataca aggcgtacga gggcgtacaa gccaaaccct tcgcaccgaa gtcgtgcatc
    45781 aactggattt gtttctgggt attaccgcta ctcatcggga tcaccgtacc accgatattc
    45841 tccactccgg catgggcacc caagcctccg gtaaacattc cgtaaccata ggatacttgc
    45901 acggaatcgt tctttgtcaa accataggcg gtcaggcaac gagccaccac ctcggcccaa
    45961 atacccaagt ccttacgggt atatcccacg acgataggct tacctgtcgt accggaagag
    46021 gcatgcagac ggacgatctc ggacatcggc acggccatca agccgaaagg atagttatca
    46081 cgcaagtctt gttttaccgt gaacggtaat ttcgttatat catctattgt ctgtatatcg
    46141 tcgggagcaa tgcccatctc ctgcattttc ttgcgataaa acggggagtt atggtaagca
    46201 tgttcaacaa ctcttttcaa ccgtaggctc tgtagtttcc gcatttcctc acggtccata
    46261 cattcaatag tttcgttcca aatcatggta tttgtctgtt atcttttaaa gttagtagtc
    46321 taaatccgcc gcaaagtaac aacttttttt aaatcggcac ccttttgtta cgaaaaatta
    46381 gtcacgaggc gatcatttca actccttcac cttgatattg cggaacgcta cctcatcccc
    46441 atgatcctgc aaaaggatgt gtcctttcgg agcctcgccg aaagcaccac ccgcattata
    46501 agatggatca gcgtatttac tgcccttcac caaatcacgg aactccttgc tgccacgctc
    46561 gtactccaat accttcacac cattcagcca gtgctctacg tggttgttcg ggaatacctt
    46621 caccacggcc gtattccact ctcctacgcc gttgaaatgg atgttctcgc ttttcttcag
    46681 atcatacaag cttccaaggg tacgactacc ggggaaagtc gtgtaaagct tggcatccgg
    46741 gtgcttagcg tcatccaata gctggaactc caagccgtaa gcggagcctt tttgcttctc
    46801 ttgctcggtc acgaagtatt taataccgct gttggcccct tcggtgatct taaaatccac
    46861 gctgaactca aaagcggaat attcaccctc cgtaacgata tcgcctccgt tcgtagactc
    46921 gctaccgtcg gatttctgca cgatcaattc gccatctttc accatccatc cgtgatccgg
    46981 gaaagcgtct ttgtgcgctc cacgccagcc tttcgttgtc ttaccatcaa aaaggagcgc
    47041 ccaaccctcg gctttctctt ggtcggtcaa ttgattgatc gccggtgtaa ttacggccat
    47101 cggtactacc ttagctgtct cttccgtgct ttgcgtgttt tttccaccgc aggcgcaaag
    47161 gatcatagcg ctcatggcgg tacaaattac tagtgtcttc atgtcttatt tatttttaat
    47221 atataatcaa gctatgtgtg cgtccacaaa gataattgat ttcataaaaa atagacgtat
    47281 cttcgcgata taaatattaa atgattattt atatgaaaca accaaagacc gccttgttcg
    47341 attttgacgg cgtagtagta gatacggaac ctatttacga tttattctgg aacgatgccg
    47401 ctaaacgtta tggcttaggt atcgataatt tcgctgatat tataaagggt acgaccctac
    47461 cgtatattct ggagaagtat ttttccggat atacggagga gttccgccaa atggtgacca
    47521 aagaatctac agagtatgag aagacgatgc ccttgcctcc catgcccggc tccatcgagt
    47581 tcatccgtat gctgaaggag cacggcgtac agataggctt ggttaccagc tcggataacg
    47641 cgaaggtgaa acgggctttc aggcttctac atctggacaa tctattcgat accctagtga
    47701 ccgccgaccg catcacgcaa ggtaagcccg atccgatgtg ttatctattg gcggcgaaag
    47761 acttgaacgt atctcccgag gattgtatcg tattcgagga ttctttcaac ggcatacagt
    47821 ccgggaagga cgcagggatg cgtgtcatcg ggttaagtac gacgaatccg gcggaatctt
    47881 taagagataa agtatatgag gtaatcccca atttcgagaa agtcacgttc gaggattatt
    47941 tgagatggta agcaatcgag aaaaaggaaa tgattatttc cttcattcct tcacctaccc
    48001 ctttacacac acccacacac atgtatgcgt acattaataa tacgcgtatg cgtgcgtgtg
    48061 tgtaggagcc ggtgaaggaa taaaggaaac gcctgtaccg tcaatgggct acaccagtat
    48121 cggcgagagc cggaagcagt actggtgtaa ccccacggca gtactgtcgt ggggctgtga
    48181 ctatattggg atcagaaact atatcctacg cgaacaccca gcatggcctg atcgaaatcc
    48241 ttgatgatat tatacttcac ctccaatcct atcgaaagat tgtcggtagc ataaacctca
    48301 ccgcctaaac cgatattggc tcccagacga gtctcgttat gagaaaggcc atggcccgca
    48361 tcccaattcc aaaaggacag actaagcccc gctaatggat aaaaaccgaa catctcactt
    48421 aacttcacta cataatgagc attcaagtcg atcgcccaag tgctgtgatt atcattcttt
    48481 acgaaataag taagagaggg gctcaaacgt accgcatccg tgatacaata gcggtaatca
    48541 actcctaacg tggcattctt cgaatcgaat ccataaccga tgttaaatcc cacggcagat
    48601 tgtccttgct gcgtctgcgc ataagctccc agactaaaga ctgctaacat cagcatcatt
    48661 acaaactttt tcatacgctt tctttcgttt agttcaacat tagattatta ttggtattta
    48721 ttttactttc agtcgatcgc cggcactctt cacgatgcta cggtaatagt cctcgtcata
    48781 tccgggaaaa tcgggagacg caggctggcc gtacggatta cgcttgaact gtccgttcac
    48841 ctctttcttc acgtttccat cgatgtattt tacaagcaaa tactcaccca attgcttcca
    48901 gcgggcggta gcggagtctg aattagtcgt gctataccac gtcaagaact tgacagcctc
    48961 cgccgggtcc ttggcataca actcctgagc cgccttatcg atagccggta cggtctcttg
    49021 ataaccattc tccaactctt gctgtacctt acggatatcc tgaatcatga agctatattt
    49081 gtggtaagcc atattagcca cccagttatg aatccagaaa gcggaagtcc aagagaagtt
    49141 cagcaaatcg ccgtttccca cccgatagca ctccggaaca tccgttaccg acccatatac
    49201 aggagtgaag actgccatat cagcgtcgtc cacggcaaac cacaagatac caccgatagc
    49261 gtccggcaac cagttacgca tttgtggaac aatcacgaag cccgtttgtt gcgtcgctat
    49321 ggcacgttca ttcgtatatt cctgcccgtc tacctcgaac gtcatcggcc gcca
//
LOCUS       DBMDTB010000016        48180 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_295_length_48180_cov_10.076769, whole genome shotgun sequence.
ACCESSION   DBMDTB010000016 DBMDTB010000000
VERSION     DBMDTB010000016.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 48180)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 48180)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48180
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_295_length_48180_cov_10.076769"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..1307)
                     /locus_tag="ACZPB4_04475"
     CDS             complement(<1..1307)
                     /locus_tag="ACZPB4_04475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HIR1097510.1"
                     /translation="MKMSGEKAIHRQELERGLLTQKISRLFLKYTIPGVAGLLFLGIQ
                     SVIDGVILGRFVGANALASVNLILPCYSLMTALSIVIGVGCQTLIGINLGRSDRQEAN
                     NAITTSFLFLGGISVLISGLIYIFAGDIARMLGANDVLVTGAVDYIRSLVPFFPLLSL
                     MFLGDYMIKAMGHPLYAMIVMGSTVLINIGLDLLFIPVMGLGIKGAGLATGLAFTLGA
                     LFNIPRMFQRGQVVAVQRGRFRWPLVWNALYNGSSEGISELSAGITIFLFNITMMRYL
                     GEDGVAAFTAINYILFIATTVFLGISDGIIPIISYNFGAGRLDRIEKVLRLAGRVNFM
                     IGITLFAILFFFGQQITSFFFKGGEALDALAIANYGITIYCFTFLMSGLNILASSYFT
                     AIGNAKLSVVISMLRSLVFVTFGIIVYPSLFGIQSIWYNVPVA"
     gene            complement(1393..1956)
                     /locus_tag="ACZPB4_04480"
     CDS             complement(1393..1956)
                     /locus_tag="ACZPB4_04480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010182830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HIR1097511.1"
                     /translation="MIMDQFVEQLRQVSPLSDEIVGQLLEEMKEVSFAKGELSIREGE
                     RDPFVWFVKTGLVRAFVEREGKDISLWFASDSEVINFVYRNISAYNVQMVENTTLLRI
                     PKTKLDYLCRSSLELANWGLKIQDYYLREYENYFINDSWMEAREQYESLLKTRPDLIL
                     KLPLKHIASYLQITPQSLSRIRASVKK"
     gene            2276..3622
                     /locus_tag="ACZPB4_04485"
     CDS             2276..3622
                     /locus_tag="ACZPB4_04485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HIR1097512.1"
                     /translation="MYNRIAGYKQYYKSLVMLGVPIIIGQLGAIITGLADTIMVGQHS
                     TEELAAASFVNNVINAFIIMGTGFSYNLTPLIGQNLAMNKKIVIGGWLKNSLVANMTT
                     TLLLIAVLLGIYLNLDSLGQPEELLPLIRPYFAVSLVSILFVMLYNSFRQFVEGIANP
                     SISMWVLLTGNLLNIIGNYILIYGKCGMPELGLLGAGISTFISRIIMLLLFIAVFMLR
                     TDYKPYRKGFTHIRINKQSWRRLNSIGWPISLQQGLEAGTFCVTAIMVGWLGSLELAA
                     HQIAITISTISFTIYLGLGAAVAIRTSYYKGANDWYMVRKITIAGLHLGLIVVCIVCT
                     TLFMTQSWLGLIFTDNLHVNAIVKTLLPILMLYQIGDSAQIILANSLRGLADVKAIMW
                     ISFLAYFIIAIPAGYLLGFTFHWGIAGIWMAYPLGFLCSVCLLGYRAKMQVKSHLA"
     gene            complement(3628..5025)
                     /locus_tag="ACZPB4_04490"
     CDS             complement(3628..5025)
                     /locus_tag="ACZPB4_04490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HIR1097513.1"
                     /translation="MDKEITNINGQTGGNIPDGLPIPSRYWAILAIGLGVTVSVLDGA
                     IANVALPTIAGDLHTSPSASIWVVNAYQLAITISLLSLSSMGEIWGYRKVYTIGLLLF
                     SCTSLACALSDSLFTLIIARTLQGFGAAAIASVNTALIRIIYPKRFLGRGMGINALVV
                     SVSAAAGPTIAAGILSVGNWPWLFAINIPIGITALILSFKFLPQNPVKAVGRKFDVTA
                     ALMNALTFGLVIAIIEAFTHDVHISLIIAAIVIVLFCGYFYIRREERQAYPLLPIDLL
                     RIPLFTLSIITSVFSFIAQMLAMVSFPFFLQRVLGRDEVATGLLLTPWPLATMVCAPL
                     AGILSEKMNAGVLSGIGLIIFSGGLFSLAELPAHPSDLDIIWRMALCGCGFGLFQTPN
                     NSLMIGAAPESRSGGASGMLGTARLLGQTCGASLVALMFKLFPGHSMPAALWLGSVLA
                     LIGAVISFSRINRKA"
     gene            5112..6461
                     /locus_tag="ACZPB4_04495"
     CDS             5112..6461
                     /locus_tag="ACZPB4_04495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent transcriptional regulator"
                     /protein_id="HIR1097514.1"
                     /translation="MAKQGTILVVDDNKGILTAVQMLLGTCFEKVITISTPNKIKNTL
                     HDENVDVVLLDMNFSAGINSGNEGLFWLSEIKKAYPSIQVVLFTAYADIDLAVRGIKE
                     GATDFVVKPWDNAKLLETLQAAYQIRSANHKGGVGNKQLVSKESGMFWGDSNAMQQLR
                     MLIEKVAKTDANILITGENGTGKEMLAREIHLLSPRKDEAMVPVDMGAITETLFESEL
                     FGHVKGAFTDARTDRPGKFEVANNGSLFLDEIGNLSYHLQAKLLTALQRRSIVRVGSN
                     TPIPINIRLICATNRDLQEMVQKEQFREDLLYRINTIHVEIPPLRERPEDIVPLTEIF
                     ITKYTNIYGKKPMALTDDAKEKLKAQPWLGNIRELEHTVEKAIIIADGDTLDGGNFDF
                     PRKREAPVKNDITTLEEMEYTMIKAAMDKFGGNLSLVANQLGISRQTLYNKIKRYEL"
     gene            6451..7770
                     /locus_tag="ACZPB4_04500"
     CDS             6451..7770
                     /locus_tag="ACZPB4_04500"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1097515.1"
                     /translation="MNFKGIYYSLTFRLALAIGLTAALTYLALAEEWGWFLFLGVGWL
                     ATLRGISLLFKRNAQKVAFMFDAIDNSDYAFKYATRGRSSNDKLVSDSLNRITQILFQ
                     AKAEAIQKEKYYELIMNQVNTGIIVEDDKGNIFQTNNEALRLLGLTVFTHARQLGRID
                     ENLERLISDVRPGEKHQISFINERGTVHLSVRVSEMTLQEKHVRIIAINDINSELDDK
                     EIESWIRLTRVLTHEIMNSVTPITSLSDTLLSLHQNVDEEIRGGLEVISSTGKSLIAF
                     VESYRKFTHIPTPQPSLFYVNKFAERLTRLARHHNNYPNITIRIDVEPKDLIVYADEN
                     LITQVVLNLLKNAMQAIGHEQENGLILFKAYCDPNEAVILEVTNNGPIIPPEEAEHIF
                     VPFFTTKEGGSGIGLSISRQIMRLSGGSIALRSNPAQRQTTFVLTFP"
     gene            8075..9328
                     /locus_tag="ACZPB4_04505"
     CDS             8075..9328
                     /locus_tag="ACZPB4_04505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008771899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HIR1097516.1"
                     /translation="MNLLDKLKINHRPRSGALDLLKYIGPGLLVTVGFIDPGNWATNL
                     AAGSEFGYALLWVVTFSSVMLIIIQHNVAHLGIVTGLCLSEATNKYMPRVLSRPILGS
                     AMLASVSTSLAEILGGAIALRMLFGMPIKAGAVIVTIVCLAMLFSNTYSKTERWIITF
                     VSIIGLSFLYELALVDVDWGQAVVGWVKPTFPENSMLIIMSVLGAVVMPHNLFLHSEV
                     IQSREWNLEDESVIKKQLKYEFYDTLLSMVIGWAINSAMIILAASTFFKQNIAVDELD
                     QAQQLLVPLVGNNAGVIFAAALLLAGISSTITSGIAGASIFAGFYGEAYNHTDLHSKL
                     GVLLSFVPALAIIFLIGDPFKGLILSQMLLSVQLPITVFTQVYLTSSKKVMGVYANSR
                     STTIILLLLGTMVTVLNIALLISLF"
     gene            9381..11120
                     /locus_tag="ACZPB4_04510"
     CDS             9381..11120
                     /locus_tag="ACZPB4_04510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004819 - glutamine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006425 - glutaminyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--tRNA ligase/YqeY domain fusion
                     protein"
                     /protein_id="HIR1097517.1"
                     /translation="MSDINTNEEEGKKNLNFIEAAVEKDLAEGKNGGRVQTRFPPEPN
                     GYLHIGHAKAICLDFGIAERHGGICNLRFDDTNPTKEDEEYVEAIKEDIQWLGYQWGN
                     IYYASDYFQQLWDFAIRLIEEGKAYIDEQTSEQIAQQKGTPTQPGIESPYRNRPIEES
                     LALFKKMNTGEIAEGAMVLRAKIDMANPNMHFRDPIIYRVVNHPHHRTGTTWKAYPMY
                     DFAHGQSDFFEGVTHSLCTLEFVVHRPLYDLFIDWLKEGEDLNDNRPRQTEFNKLNLS
                     YTLMSKRNLLTLVKENLVNGWDDPRMPTICGFRRRGYSPESIRKFIDKIGYTTYDALN
                     EFALLESAVREDLNARAIRVSAVINPVKLIITNYPEGQVEELEAINNPEDPEAGSHTI
                     EFSRELWMEREDFMEDAPKKYFRMTPGQEVRLKNAYIVKCTGCKKDENGEITEVYCEY
                     DPNTRSGMPDANRKVKGTLHWVSCAHCQKAEVRLYDRLWKVENPRDELAAIREEKNCS
                     PLEAMKEIINPNSLEIRKNCYVEKFVATLPKLSYLQFQRIGYFNIDSESTPDNLVFNR
                     TVGLKDTWSKINK"
     gene            11131..12588
                     /locus_tag="ACZPB4_04515"
     CDS             11131..12588
                     /locus_tag="ACZPB4_04515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HIR1097518.1"
                     /translation="MKKDDISRLLQHYLSAKEEGKEPYFDADQIDEMLDSFEDSNDYT
                     YFDEVLALGLKLHPGNSALQIKKGRQFAYNEDYESALALLENIAETDNQDLDMLKMEC
                     YCSLNQYPKVLEITEELITRDCDYLEEVFEYISPILNDLDMNKEARDFVDRGLALFPD
                     NLILKNELCYILETEGDVPRAIELCNELIDKNPFSYEYWFTLGRLHSMVGDYEKAIEA
                     FDFALTCDDSDTELKILKAYCLYMNESYEKAIEEYQEIEGDEEVMRRISPLMAECYMK
                     LEQYEKAYQLLSTIINDPDMEDGPTNYINYIRCCTETERDNEASIMLFKAAQLYPNNV
                     RLLSLLALCLLDSGKKEEAIAITNKIFKIIDKKSINPETQEECNSLLHAGQYLLSKGD
                     IDKAISYYKKVLQINPKTPMIHIHLAMAYLDNRDMENFMEHIGQISGDDLLYLLRKVG
                     PEVFADFTIDSDKEKKHIQPEDLVKEFLKNKDNSN"
     gene            12606..13523
                     /locus_tag="ACZPB4_04520"
     CDS             12606..13523
                     /locus_tag="ACZPB4_04520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HIR1097519.1"
                     /translation="MPNKRNLKDYGFLVLKGMGMGAADVVPGVSGGTIAFIVGIYEEL
                     IDSIKSINGTTLKQLFTGKIAAFWKGINANFLLSIVGGIGISIFSLAKIITYLLVYHP
                     ILVWSFFFGLVLASTWFVSKDIKQWNWKTILSFVVGAVIAFYITVATPAETPSNLLFI
                     FLCGAIAICAMILPGISGSFILVLLGKYFYIMEAVKTFNVPVMLVFIAGAAIGITTFS
                     RVLSFALRKFHDITIAVLAGFMLGSLNKVWPWKETIETYVDSHGMTKPLVEANIAPNQ
                     FVWEAVGLMILGFGIVYFLEKLSQKSAKA"
     gene            complement(13635..15038)
                     /locus_tag="ACZPB4_04525"
     CDS             complement(13635..15038)
                     /locus_tag="ACZPB4_04525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HIR1097520.1"
                     /translation="MIYDSFLLYRHEVSRLSRSLRFRVSFVLIGLLFAGGSRLFVSFY
                     TEQQATYRQLEEDEERRDRELSENLTNYANSLRIFRYSPRTDGFLYSCKEEEMVNTIQ
                     YNVWNAGGLEIEQGMLNPLLDAKSSVDWTFIVSIFISFIALLFSYDSICGEKRDKVLG
                     YLLSYPISRRNYWISKILSHISVVMLLLLGGIFVGLLALGNMLPSIYTPSLIYKILGF
                     IGISFLLISLCTCFGLFASVMTRHSSVSLLMCVSFWLFGTIIIPNSATFWGDVLYPSP
                     LLRDIAQKVEEEESRLTKEAPPGSMAQERDDPFYPYHERRATLFMKKKEVREKSYRDY
                     YECLIRQFEGVRRLTLLSPTVQYERAMEALLGGGHLRFQKNWRDLQAFQLTFLAWFKQ
                     KDAEDPESPHWYNPYEDVSTSRKSFDIKEAPRYQERSVPLKERLALIGLYALTTFFFI
                     ALLVWGGFRLLEKYDVR"
     gene            complement(15025..16614)
                     /locus_tag="ACZPB4_04530"
     CDS             complement(15025..16614)
                     /locus_tag="ACZPB4_04530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HIR1097521.1"
                     /translation="MRNIWIFAWKEFRLNIRSARFAIGLLLCLVIVPFTMMVGIGDYQ
                     IQKEVCEAEARQAEEEISSCLVWSKVHPKLVREPEPLSLLSRGITNNIGYTVLITLWE
                     IPFLPFQFNWAQNSPFMKVFPPLDFSAVLSIMISLLALVFSYDTVTREREEGTLRFIF
                     SSSVSRYSFLVGKWLGVVLTVLPILLACFLMGLGFVVLEGGVRFSGSEWVGIGWMLLA
                     SFVYLAFFGSFGIWVSSLTARSVTSIVLCMLSWLTFLFVIPALSSYASRSMVALPSYK
                     QVENKKVELFWSMRSEYDKRWRELRDSLGLQSLRYLFDVEDGEGTKDIRGGSRLVLEH
                     TRRMAVVDANIRIDHAERLWKLDEEYLCTLSAQRKWQDILNLLSPSATYIRLMARLGN
                     TDADALLSYMSDARNYREQFIRYLTDRELFYSPSYVTPCREDEFLPQEEWEAFERQAE
                     KLQKNDPPAFERIMKDAEQQYADANYSPVDVRDIPQFSLRELSGWQRAQRGARSLILL
                     FILFIALLASAIYIFRRYDLR"
     gene            complement(16611..17324)
                     /locus_tag="ACZPB4_04535"
     CDS             complement(16611..17324)
                     /locus_tag="ACZPB4_04535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008771893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1097522.1"
                     /translation="MLEAIDLTKRYEDGHLALDALNLRIEPGEIFFLLGANGAGKSTT
                     LNLFLDFIRPTSGRALVNGVEVRSNPAETRRHIAYVSENVMLYGDFTARENLDFFTRL
                     TGKRLDRRDYYQAMRRVGLPEESFERKLKTFSKGMRQKVEIAALLLKDADNMVMDEPT
                     SGLDPRSTAELMQLLHHLRLEGKSILICTHDLFRARSLADRVGIMKDGRLVMVRSRDE
                     FLRDDLERIYLDYMQEAVL"
     gene            complement(17338..19662)
                     /locus_tag="ACZPB4_04540"
     CDS             complement(17338..19662)
                     /locus_tag="ACZPB4_04540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane beta-barrel family protein"
                     /protein_id="HIR1097523.1"
                     /translation="MRKKAVILLAILIAIFGGSVNAQSFLGKLVDDKEAPVGFANVVL
                     LNPEDSAFVKGTVSEESGEFVLEGLKEQCYILRVSYIGYKDICLECPKAGDVGTIRLE
                     PDAIALGEAVVTGKLPTYQLKGSSLVTNIQETLLSTVGTANDVLSHIPGLESSDGKYT
                     VFGKGEPLIYINNRLVRDNSELERLSSKDISKVELIQNPGAEYDATVKAVLKIRTVRH
                     AGEGLGVNVRSNVSQSHKTSNTDQLNLNYRKNGLDLFGMVNYSLWQAQTRQRTSSYIQ
                     VDTLWEQKAETTVDQSSRSVYGQLGANYEVNEHHSFGATYEGNKGFNSGGDFVSDNTM
                     YANKTVYDVLHYQTRMETDVNQHKVNAYYEGRFNDKLTISFNADWLTGSSENRMFANE
                     NSEMDDDRLVTTSNRTRNRLYAVKLVMTYPIAVGELKWGGEYSYVHRTDRFDNPQSIL
                     PATDSKIREQNAAAFISYALTWQKLSAEIGLRYEHVDFDYYDKGIFLPEQSRLYDNVF
                     PNVALSMPIGKTQMSLSYTAKTSRPSFYQLRSDLQYDDRFTYEGGNPLLKPSFNHDLT
                     YQFGYKFIQASLNYQYIKDVSSFMMKAYEPDPVITVFSQENYPKAQYLNASVSFSPKF
                     NFWEPSLYLSVSKPFFEAFTMGEMRSFNKPTYGFSLNNSFRLPKGWIFSLDGRVSTDG
                     DSMQSLSKRTGGVYVGLRKSFLKDEALTLNLQGFDIFATQRYSFVMYAADRSMTKWSN
                     PDSRQVRLTVTYRFNATRSKYKGSGAANEVINRL"
     gene            20095..21345
                     /locus_tag="ACZPB4_04545"
     CDS             20095..21345
                     /locus_tag="ACZPB4_04545"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008771891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing sensor histidine kinase"
                     /protein_id="HIR1097524.1"
                     /translation="MLSLFKRHTNTPQPELSKMLSEFNRSLMLIADKSLLINNFISKI
                     RQICPVEIIHLFLLDENTGKYKPQDGPLSSSLSFNGKDKLISWLFVNERSLLLSQNPD
                     IADYFTAEEREKLEQLQAELIYPLKVMNKVSGVIMLGKKTDRTGFTENELGLLSLLFN
                     QAAFAIEHASLYEIQSERIKKMYRTDRLATLGELAAGAAHEIRNPLTAIRSTIQYLSK
                     DFSADPVKSEMATELISEVERINKIVQGLLSFARPSALNSSEVNLEQLINQTLLLVHN
                     TLKKQQVEVEFEYFHENTALQADAEQLKQVFLNIILNAVEAMSQNPPERSRTLIISIE
                     KGASIDDHSHYLLLSFEDSGKGIGEKDLDHIFNPFFTTKDEGTGLGLAICYGIINRHE
                     GEIEVHSTPGKGTCFTIKLPQYIV"
     gene            21342..22709
                     /locus_tag="ACZPB4_04550"
     CDS             21342..22709
                     /locus_tag="ACZPB4_04550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent transcriptional regulator"
                     /protein_id="HIR1097525.1"
                     /translation="MKAKIVVADDEPRIRAMIALLLKEDGYEVQTAANGQEAVDALLS
                     FRPDVILLDQQMPVLTGVEALEKIKRLCPNQVVVFITAFGSVSLAVDAVKKGAYDFIE
                     KPFDNDKLLLTVSRAVEHCRMKGEIKHLKNKLGDMNTGIIGEKSGLRQVMLQVGRVAE
                     TDATVLIHGESGTGKELIAWAIHDRSKRVSQPFVAINCGAIPLTLMESELFGHEKGAF
                     TDAKETQAGTFERANGGTLFLDEIGELPLDAQVKLLRVLEERKITRIGGKKAIPVNVR
                     IVAATNRNLEEEVRLGKFRLDLLYRLNVFTIQLPPLRERKEDIPLLAAFFLRKHNSLL
                     NLSIESITPEAMDQLCAYDWPGNVRDLENAVQSAMILCVNRQIHPGHLPARIKSYQME
                     RLIAPQEAEEDTSLRDTNSLAEKTRILSALQKHNYNRTLTAEALNISRKTLFNKMKRY
                     NLGNE"
     gene            22775..23002
                     /locus_tag="ACZPB4_04555"
     CDS             22775..23002
                     /locus_tag="ACZPB4_04555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007653280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HIR1097526.1"
                     /translation="MAKIKGAVVVNTERCKGCNLCVVACPSDVLELHPREVNNKGYHY
                     VYMKNPDACIGCASCGLVCPDGCLTIYKVKI"
     gene            23017..24096
                     /locus_tag="ACZPB4_04560"
     CDS             23017..24096
                     /locus_tag="ACZPB4_04560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008771889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HIR1097527.1"
                     /translation="MAEDIKLMKGNEAIAHAAIRYGVDGYFGYPITPQSEILETLMAE
                     MPWEKTGMVVLQAESEVAAINMVYGGAGSGKKVMTSSSSPGVSLKQEGISYIAGAELP
                     CLIVNVMRGGPGLGTIQPSQADYFQTVKGGGHGDYRLITLAPSSVQEMADFVGLGFDL
                     AFKYNNPAIILADGIIGQMMEKVVMPPYQPRRTEEEIIAQCPWAVQGKKGGRKGNVIT
                     SLELDPAKMEENNIRFQAKYRKIEENEVRYEEFQCEDADYLLIAFGSSARICQKVVEI
                     ARAEGIKLGLLRPITLWPFPTKVIAAYADKVKGMLSVELNAGQMVEDVRLAVNGKVKV
                     EHFGRLGGIVFTPDEVLNALKEKLF"
     gene            24102..24272
                     /locus_tag="ACZPB4_04565"
     CDS             24102..24272
                     /locus_tag="ACZPB4_04565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097528.1"
                     /translation="MTRGSKADEILTLVFMLLAIAAVVCYFAVSDKAVFLYCGGAAIV
                     LRLVQYVLRYIH"
     gene            24285..25049
                     /locus_tag="ACZPB4_04570"
     CDS             24285..25049
                     /locus_tag="ACZPB4_04570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent enzyme"
                     /protein_id="HIR1097529.1"
                     /translation="MELNDIIKPENLVYEKPRLMNENPMHYCPGCSHGVIHKLIAEVI
                     ADMGLEDKTIGISPVGCAVFAYNYLDIDWIEAAHGRAPAIASAVKRLNPEKMVFTYQG
                     DGDLAAIGTAETIHAANRGENIVIVFVNNAIYGMTGGQMAPTTLEGMPTATCPYGRNI
                     ALNGYPLKIGDLLAQLEGTCLVTRQSVQTAAAVRKAKKMLRKAFENAMAGKGTSVVEF
                     VSTCSSGWKMTPEKANKWMEANMFPFYPLGDLKNVE"
     gene            25068..25610
                     /locus_tag="ACZPB4_04575"
     CDS             25068..25610
                     /locus_tag="ACZPB4_04575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005654927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016903 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HIR1097530.1"
                     /translation="MKQEIIIAGFGGQGVLSMGKILAYSGLMEGKEVSWMPSYGPEQR
                     GGTANVTVILSDERISSPVLNEYDIAIILNQPSMDKFENKVKPGGILIYDGYGIHTPA
                     KRTDINVYRVDAMDAATEMKNEKAFNMLILGGLLNIVPMVQLENVMLGLKKSLPERHH
                     HLLPMNEAAIKKGMEIIQKI"
     gene            25715..27796
                     /locus_tag="ACZPB4_04580"
     CDS             25715..27796
                     /locus_tag="ACZPB4_04580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative porin"
                     /protein_id="HIR1097531.1"
                     /translation="MKYYLYILLFLIGTAASAHAQGRSGSRGGRGGFSLSNLSSSNKE
                     IPDSLLQTDSAALKSKRIIGYRLTPLLGERYIAPMDTNRLNFGNSTLVEANSLAVGYL
                     ANVGSPAQTRIFNERKEERDFIFADAYDYYITTPTNAYFYDTKVPYTQVTYTTGGASQ
                     NKMDRLKGVLTMNFGKKINVGGEMDYIYSRGYYNSNGNKLLSYRFFGSYITDRYELNA
                     YLSNFNFVNYENGGLTNDQYITNPDDLAENQRNIDSKSYPVRYTDTWNRVRGKQYFLT
                     QRYNLGFTKELEETDEEGNIKEVFIPVSSIIHTIDYEDNRRRFISNDAGIDTCYTHLY
                     GMDASLNDQTSSWNLKNTFALALREGFQDWAKFGLTAFVTFEKRRFRLASQVPGLDYG
                     PDGRGSSEPSTLNFPTSEVYDEFTTYIGGELSKRRGSLLTYNVRGELGLAGSDAGEVR
                     VSGDLQTKFKLFKKDATIKAEGYIKNITPAFYQRHHHGRYYWWDLSLKNVQRIYAGAK
                     INLESTRTQLSGGVESIQNYVFFNGKGLPEQSNKNIQVVSARIKQDIMYRAFGWENEV
                     AYQLSSEKSQLPLPDISAYSNIYLAFKLAKVLTVQIGANIYYNTAYYAPYYEPATQQF
                     QVQEEDKKVKVGNYPLINAYANFHLKQARFFIMAYNLGSKFVDPNYFSLAHYPLDPMV
                     LKMGISVTFNN"
     gene            27806..28630
                     /locus_tag="ACZPB4_04585"
     CDS             27806..28630
                     /locus_tag="ACZPB4_04585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008771887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HIR1097532.1"
                     /translation="MRSKKLLILYAFLLIVAVVTMVQLWRLNQRPQEIGPRDYPEIKE
                     EGILRMITEYNQSGYFVSGDTVQGFQYELSQAIAKLSGLEVQTHLEMSLAKSFEELSD
                     NKCDVIARNIPITSEMRENYLFTEPIVLNKQVLVQRTAEANNGQAPIRNQLDLAQKTL
                     YIPKDSPALLRLQNLGHEIGDTIYVVEDELYSTEQLMIMVAKGDIDYAVCDQQIARMT
                     QKNLPEVDILTDVSFTQLQSWAVRKDSPVLLDSLNSWLQQIKNSGLYDQIYKRYYK"
     gene            complement(28633..30501)
                     /locus_tag="ACZPB4_04590"
     CDS             complement(28633..30501)
                     /locus_tag="ACZPB4_04590"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing sensor histidine kinase"
                     /protein_id="HIR1097533.1"
                     /translation="MNSLESGSNVQSGLEMIMEKSPDTIVLVDRNLTLVKVISAKDDY
                     YHYLANNCIGKQPQALFPDGKNYDQYEIYRAAVKRVFEEQVKVDFSFEVSFEGKNYYY
                     LSQASLFNEELVIVYTRDVSSLKTEKNLQELINTILDRLPLGVFVKDGDNHFNYLYWN
                     HFMEEITGIETREIEGHDDFEVNYNALMTAEERLETDMNVIKTGLTARFKGKVKSASG
                     DYRDIEVAKYPISLNNGKPLVLALWRDITSELATENTLRRTRILTKMALRISDIRTCS
                     IFIDPDSTHNFKDSVVTLNDWNTMSEDMIEVSWGQFISRAHPDDQEHYHNMFTRLCRG
                     EISEARIEARMLFPGKKEYVWREVFATVYERDEKGRPSVILGCSTNIQERKNQELSLE
                     EAKVKAEAADKMKSKYLADMSHEIRTPLNAITGFSELMAFADTDEERMSYYDVIKMNN
                     QLLMQLINDILDISKIEADAIKITYEQLDVSELMDTIYASAKLRVPGGVKLVLEKGAD
                     HHMFGTDSMRLLQLINNLVNNAIKNTKEGSITMGYTIQPDNQLRFYVRDTGIGIDKDK
                     LKDVFGRFVKINDYMEGIGLGLAICKGLVVKMGGSIHVTSELGVGSEFSFILPSHE"
     gene            30638..31918
                     /locus_tag="ACZPB4_04595"
     CDS             30638..31918
                     /locus_tag="ACZPB4_04595"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HIR1097534.1"
                     /translation="MRFDELDLEDAVLDGLYDMNFDETTPVQELTIPVILEGKDIIAC
                     AQTGTGKTAAYVLPVINELSKGCHPTDAVNAVIMAPTRELAQQIDQQIQGFTYFIPSI
                     SAVAVYGGTDGIAWEQQKRGLEMGADIVIATPGRLLSHIKLGTVDLSKVSFFVLDEAD
                     RMLDMGFYDDIMQVHKQLPPYCQTIMFSATMPPKIRTLAKTILKDPEEVKIAISRPPE
                     SIMQTAYICYDPQKLKILQDLFTQSRPQRVIIFSSSKMKVKELASTLKRLKFNVAAMH
                     SDLEQSQREEVMKEFKSGHIDILVATDVVARGIDINDIKLVVNFDIPHDPEDYVHRIG
                     RTARGTNGEGLAITFVSIDEQAQFKRIEDFLEKEVYKIPVSPEFGEVPLYEPEKYGMN
                     KRGRGRPRKSEDKGSSSSPQKRNMGHRGRPKKAQ"
     gene            complement(32015..33997)
                     /gene="rho"
                     /locus_tag="ACZPB4_04600"
     CDS             complement(32015..33997)
                     /gene="rho"
                     /locus_tag="ACZPB4_04600"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008186 - ATP-dependent activity, acting
                     on RNA [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HIR1097535.1"
                     /translation="MQKYNILELNEKLLPELQSIAEELGIKKVSSLKKEELVYRILDE
                     QAISYAGIQAEKMKEKEAKKPVEGRKRGRPAKAASPKVAKAETAEAAESAQQASEKPV
                     AAPADKKEQKEQPERKKRVRIEKKEKVAGAIAPSEDNKEVVVSKEPQTISMVTEISAV
                     ETPAVVESPVEKPLLPPVVAELETEEEAALPENTTPVEVAEETTSPQATEEEPKRIVF
                     RHPDAKSVLDQIFPFSAPKPEANKPQPEAAPQQNNPRQNNRQNNHNNNRNNNNANNNQ
                     QAQEKMYEFDGILTGTGVLEMMQDGYGFLRSSDYNYLTSPDDIYVSQSQIKLFGLKTG
                     DVVEGSIRPPKEGEKYFPLVKVDKINGRTPEEVRDRVPFDHLTPLFPDEKFMLTARKS
                     PKVYDNIAVRVVDLFSPIGKGQRGLIVAQPKTGKTMLLKDIANAIAYNHPEVYMIILL
                     IDERPEEVTDMARSVDAEVIASTFDEPAERHVKIAEIVLNKAKRMVECGHDVVILLDS
                     ITRLARAYNTVQPASGKVLSGGVDANALQKPKRFFGAARNIENGGSLTILATALTETG
                     SKMDDVIFEEFKGTGNMELQLDRKLSNKRIYPAVDITASSTRRDDLLQDESTLNRMWV
                     LRKYLSDMNSMEAMEFVKQRMEQTVDNMEFLASMNG"
     gene            complement(34199..35515)
                     /gene="tilS"
                     /locus_tag="ACZPB4_04605"
     CDS             complement(34199..35515)
                     /gene="tilS"
                     /locus_tag="ACZPB4_04605"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HIR1097536.1"
                     /translation="MIHTIRLYIEKYRLLSEDRPVLVGLSGGADSVALLGVLVRLGYP
                     CIALHCNFHLRGEESDRDEAFACEFAESLEVPFHKIDFDTISYAGERHLSIEMAAREL
                     RYAWFEEMRERLGGQATAVAHHRDDNVETVLMNLIRGTGIRGMSGIRPRNGFIVRPLL
                     CVSREDILAWLADQGYAYMVDSTNLSDAYTRNFIRLNVLPLLEEINPSARNTIARSAE
                     HLSAAETIYIYVLEQARKEVVVSDDRLSIGALMRFPAPETILYELLKEYGFTRLVSDD
                     IFAALTKEPGKLFYSSTHRLLKDRDYLWITSLEKKEKRTFVLDPEKGINHEPIELSFQ
                     KLVITIDFPIEKNKRIAYLDYDKLDFPLTLRTWKEGDWFIPFGMKGRKKLSDYFSDHK
                     FSRIEKERTWLLCSGDAIVWVVGERTDNRFRIDESTKRVLIVNFFG"
     gene            complement(35589..36353)
                     /locus_tag="ACZPB4_04610"
     CDS             complement(35589..36353)
                     /locus_tag="ACZPB4_04610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HIR1097537.1"
                     /translation="MATDKQSAEKEYTVEEKLSTLYQLQTMMTEIDKIKTLRGELPLE
                     VQDLEDEIAGLETRLQNYQAEIKEFEASVVEQKHKITESTTLIDRYKAQLDNVRNNRE
                     FDNLSKEIEFQGLEIEFSEKKIREFGEAVDAKKKDIAELTEKLEGRKADLVQKKSELE
                     QIISETKQDEEKLREKAKKLEATIEPRLLTAFKRIRKGARNGLAVVYVQRGACGGCFN
                     KIPPQKQLDIKLRKKIIVCEYCGRIMIDPELAGVED"
     gene            complement(36355..37452)
                     /locus_tag="ACZPB4_04615"
     CDS             complement(36355..37452)
                     /locus_tag="ACZPB4_04615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051540 - metal cluster binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HIR1097538.1"
                     /translation="MVKVKDILREIEHYAPLPLQEGFDNAGVQVGDVNQHATGVLLCL
                     DVTEEVLDEAIEMGYNLIISHHPLAFKSFKSLTGSNYIERCMMKACKYDLVVYAAHTN
                     LDNAVGGVNYRLAELIGLQNVRILSPQKGALLKLVTFVPEAYAEIMRNTLFNAGAGSI
                     GNYDACSYNLHGEGTFRANAGCNPFCGEIGELHVEKEVRIEMILPAFKKTAVTRALLS
                     VHPYEEPAFDFYSLSNTWEQAGSGVVGELPAEEDELSFLLRIKALFNVGCVKHSPFTG
                     KPIREVAICGGSGAFLIKDAIAYGADVFITGEAKYNDFYDVEDRILLAVIGHYESEIC
                     TKDIFYNIISKKFPTFAVHFSNVNSNPVKYL"
     gene            complement(37564..39321)
                     /gene="aspS"
                     /locus_tag="ACZPB4_04620"
     CDS             complement(37564..39321)
                     /gene="aspS"
                     /locus_tag="ACZPB4_04620"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013616724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HIR1097539.1"
                     /translation="MYRTRTCGDLRLADEGLVVTLAGWVQKTRKMGGMTFVDIRDRYG
                     ITQLVFNQEVDAALCEKANKLGREFVIQVTGTVRERSSKNAHIPTGDIELIVSELNVL
                     NTALTPPFTIEEETDGGDDLRMKYRYLDLRRACVRKNLELRHRMAFEVRRYLDEQGFL
                     EVETPVLVNSTPEGARDFVVPSRMNPGQFYALPQSPQTLKQLLMVSGFDRYFQIVKCF
                     RDEDLRADRQPEFTQIDCEMSFVEQEDVLNMFEGMAKHLFKVIRGVEFKESFMRMTWQ
                     DAMKQYGSDKPDLRFGMKFVELMDIMKGHGFSVFDNAAYIGGICAEGAASYTRKQLDA
                     LTEFVKRPQVGAKGLVYARVEADGNVKSSVDKFYSQEVLQEMKNAFGAKPGDLILILS
                     GDDAMKTRKQLCELRLEMGNQLGLRDKDKFVCLWVIDFPLFEWNEDDQRFYAMHHPFT
                     SPNPDDIPLLDTDPGAVRANAYDMVINGVEVGGGSIRIHDSQLQDKMFKLLGFTEERA
                     QEQFGFLMNAFKYGAPPHGGLAYGLDRFVSLFAGLDSIRDCIAFPKNNSGRDVMLDAP
                     GVLDPAQLDELNLIVDIKK"
     gene            complement(39442..39615)
                     /locus_tag="ACZPB4_04625"
     CDS             complement(39442..39615)
                     /locus_tag="ACZPB4_04625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097540.1"
                     /translation="MRTNDSKTSVDSKLEEMEEKYPVEQIAVKNEKKITAKDVKEAVK
                     EINPDTDSLGSRG"
     gene            39702..39839
                     /locus_tag="ACZPB4_04630"
     CDS             39702..39839
                     /locus_tag="ACZPB4_04630"
                     /EC_number="3.1.27.-"
                     /inference="COORDINATES: protein motif:HMM:NF014043.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HepT-like ribonuclease domain-containing
                     protein"
                     /protein_id="HIR1097541.1"
                     /translation="MEGVMGMRDIIAHHYFDIDAVIVFDVMKNNLPAIKMTIDKMLFD
                     I"
     gene            complement(39884..40696)
                     /locus_tag="ACZPB4_04635"
     CDS             complement(39884..40696)
                     /locus_tag="ACZPB4_04635"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009101 - glycoprotein biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HIR1097542.1"
                     /translation="MLFSVLLSLYHKESPLFLRQSLTSIFTQTLLPIEVVLVEDGPLT
                     DELYAVIKEFTSQHPELKVISLPTNRGLGKALNEGLKHCSYDLVARMDTDDIAKPDRF
                     EKQLAIFLEHPEIDVVGAWIDEFEGEVSNVLSMRKVPEQHENILRFAKGRCPVNHPVV
                     MFRKSAVLKAGGYKHFPLFEDYYLWVRMLMNGARFYNIQESLLFFRFSPDMFRRRGGW
                     RYAVTEVRLQTLFYKMGFIGFFSLLKNVCIRLVTRLLPNGLRSLLYKRLIRG"
     gene            complement(40919..41716)
                     /locus_tag="ACZPB4_04640"
     CDS             complement(40919..41716)
                     /locus_tag="ACZPB4_04640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097543.1"
                     /translation="MDKRLSIYVSSPDSYSDVLAVFLKGYRRYWSDCPYEFILTTNTK
                     SYEGITCICNNKQNDTWVERTIAALPVIKSKYVMLMCDDIILSDNVDNSLIERLLDYM
                     DSHEIRYCNLGPTPKGSKIKSFPLLRSVNKQIPYAINLQFGIFRKDLFVELLGDGSLS
                     AWDIENSINEQAAVAPSEDYKDVVAVSEYILPYIHGVYKGKWIRHAVENLSRLSLYID
                     SGRGIVPLSQQIKIDMTNWLQWKISPKQRRALKNVLSRVGMKFATKR"
     gene            complement(41720..42289)
                     /gene="rfbC"
                     /locus_tag="ACZPB4_04645"
     CDS             complement(41720..42289)
                     /gene="rfbC"
                     /locus_tag="ACZPB4_04645"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008830 - dTDP-4-dehydrorhamnose
                     3,5-epimerase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HIR1097544.1"
                     /translation="MIQKFEFKGLDMKGAYEITPFYATDERGGFIKDYNIDAFKQNGI
                     DHELKEVFYTISKKGVIRAMHFQLVKQQAKLVRCISGHVYDVIIDLRPDSPTFGKWQG
                     FDLTGENQKALYIPQYFGHGYLVLEDSVVSYKCGEVFYGEGDAGIMYNDPDMAIEWPF
                     DKIGGIEKLIISDKDKNLMSLKEYIEKVQ"
     gene            complement(42301..43209)
                     /locus_tag="ACZPB4_04650"
     CDS             complement(42301..43209)
                     /locus_tag="ACZPB4_04650"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HIR1097545.1"
                     /translation="MKNVIVTGGNGFIGSSLIKKLIEKGTRVVAVDITFHGNRLPDSN
                     LITRIESGVNTSLVERLPVIEYDSFYHFAWKGVNGADKADPTVQLSNIQMAVDCANIC
                     KRLNVKKFLCAGTVAENVAFSLSHLKKTTGGMMYGVAKHACRIILEDYCKNIAQQFVW
                     MQFSNIYGVGNKTGNLVSYTLGELMAGKEAAFGPALQPYDFIYVDDLIEAVYRLGFKE
                     TNKPFYYIGSGNPRVLKDYLIRIGELVGCADKVGIGVREDDGVKYTMDMFDNSNLVST
                     IGEYASIDFDKGIDKTINWLKNSLML"
     gene            complement(43217..44284)
                     /gene="rfbG"
                     /locus_tag="ACZPB4_04655"
     CDS             complement(43217..44284)
                     /gene="rfbG"
                     /locus_tag="ACZPB4_04655"
                     /EC_number="4.2.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047733 - CDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glucose 4,6-dehydratase"
                     /protein_id="HIR1097546.1"
                     /translation="MGNILDFYKGKRIFLTGHTGFKGSWMCRILANAGAVVTGYSLEA
                     PTEPSLFQIANIEDDIHSVIGDIRDYASLKKAFDESQPEIVLHLAAQPIVRDSYKDPA
                     YTYETNVMGTVNILECVRNNCCVKSFLNVTTDKVYLNREWSWGYRENEELDGYDPYSN
                     SKSCSELVTHSYKRSFFTDIDGLPIIPISTARAGNVIGGGDFASDRIIPDCIRAAVKH
                     EDIVVRNPYSTRPYQHVLEPLYAYLLIAMKQYEDIGFADYYNVGPDDVDCFQTGALVD
                     LFVNKWGEGMRWVNKYDGGPHEANFLKLDCSKLKKTFGWSPRWNLDEAMEKIVEWSKV
                     WLAGGDVRVCMDKQIDEFLNV"
     gene            complement(44300..45115)
                     /gene="rfbF"
                     /locus_tag="ACZPB4_04660"
     CDS             complement(44300..45115)
                     /gene="rfbF"
                     /locus_tag="ACZPB4_04660"
                     /EC_number="2.7.7.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047343 - glucose-1-phosphate
                     cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate cytidylyltransferase"
                     /protein_id="HIR1097547.1"
                     /translation="MKVVLLAGGFGSRISEESQFKPKPMIEIGGMPILWHIMKEYAYY
                     GYTEFIICAGYKQEYIKEWFANYFLHNSDVTFDYRGGNNEMTVHQTIMEPWKVTVVDT
                     GYNTMTGGRIKRIQRYIENETFLMTYGDGVCDVEIDKLVEFHKSHGKLATLTAVKIAQ
                     DKGVLDITKDQAVRAFREKNASDGAPINAGYMVLEPEVFDMLEGGDSCVFEKTALVRL
                     AQEGQLMSYIHTGFWQCMDNIREKSMLEKLLAEDKAPWKRWERSVPEIPDYAK"
     gene            complement(45164..45994)
                     /locus_tag="ACZPB4_04665"
     CDS             complement(45164..45994)
                     /locus_tag="ACZPB4_04665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LicD family protein"
                     /protein_id="HIR1097548.1"
                     /translation="MNVDIKDFQYKILEIAFYFDEFCKKYDIEYYLMGGSALGAVRHH
                     GFIPWDDDFDVFMTFNNYHKFLHYASIHLDTEKFHLQRENSTEWPLFFSKLRMNGTTC
                     IEKGYNKMHQGICIDIMCLYNVSPNKFVRYIQYLSAQILKATSLYLVDYDSDSFFKKV
                     FINSCHFVVGTTAKNFLFKILNHFSTKNTLLVGHFFGKAPFPKTSFPRKWLGIQRYVN
                     FENLLLPIPFEAEKYLSLRYGSDFMKIPNSDIFTEYPIHAVFVDIHNDYTIYKDKFNS
                     "
     gene            complement(46004..46423)
                     /locus_tag="ACZPB4_04670"
     CDS             complement(46004..46423)
                     /locus_tag="ACZPB4_04670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylyltransferase/cytidyltransferase family
                     protein"
                     /protein_id="HIR1097549.1"
                     /translation="MCHENFIIGYTSGVFDMFHIGHLNILKRAKELCDFLIVGVSTDE
                     LVREYKHKSPIISYDNRKAIVEACKYVDKVVPQVNRDKMSAYHRLHFDVMFVGDDWKG
                     NSLFQEVEAELNKNGAKVVYFPYTKGISSTILRDKLV"
     gene            complement(46433..47608)
                     /locus_tag="ACZPB4_04675"
     CDS             complement(46433..47608)
                     /locus_tag="ACZPB4_04675"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HIR1097550.1"
                     /translation="MNILFISLLDPSESGSGNQKVTLLSAKYLSSVGIHCFIAYFKDS
                     EYSSSQLVFDAKFKIDYNDLDGFRSFLIDNEISIIHNQASRAVNMKFLGQAVAGLKVK
                     IISVLHNLPGTENIRYNKQSLLFQVLNRRISFKWLIYLLLLFFYPITRFLVKYITKRK
                     YKSIYKYSDALVLLSDAYIPIYRSIANLKDSSKMVSIPNFLSFDYVERNYSKTNELLI
                     VARFDEISKRILLALKIWKHFLSTYDVRDWCLTIVGYGEWESVYKDFINKNDIVNVKL
                     VGRDDSKKYFERSSILMFTSLLEGAPLSLLEAMQMKVVPIAFDDCMAIRGFLINDVNS
                     KVIKSLDISEYSRSIYDLITNEKLRCKLSENAFNCLHYFTVKNVMLRWVDLYNSLLK"
     gene            complement(47605..>48180)
                     /locus_tag="ACZPB4_04680"
     CDS             complement(47605..>48180)
                     /locus_tag="ACZPB4_04680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine inositolphosphorylceramide
                     transferase family protein"
                     /protein_id="HIR1097551.1"
                     /translation="RGDTLDEVYIVPENSYSTELNVYKYNTLLHSCEHFSTMLPVAVA
                     DATILPYNGAFYLFATSRNAYNKDLYMWTSNNRLYGYDLSPILIKSNLFGSRMAGDFM
                     YVNNTVYRPAQDCLQGYGKGIILYKVEDISDKSYNETKVISLYPDSSSYYSDGLHTIN
                     FYKSICVIDGYKNHYIPFQKIYRKLFDKYRS"
BASE COUNT        13997 a        11799 c         9973 g        12411 t
ORIGIN      
        1 tccgccaccg gtacattata ccaaatactt tggatgccga ataaagaagg ataaacgata
       61 ataccaaagg ttacgaatac caagctacgc agcatagaga taacaaccga caacttagca
      121 ttgccgatag ccgtgaaata actggaggcc aatatattca gcccactcat caagaaggtg
      181 aagcaataaa tcgttatgcc gtaattagcg atcgccaaag cgtccaaagc ctctcctccc
      241 ttaaagaaaa aggacgtgat ctgttgcccg aaaaagaata agatggcgaa taacgttata
      301 cctatcataa aattaacacg ccctgctaat ctcagcactt tctcgatccg gtccaatctt
      361 cccgccccga aattataact gataatcggt ataattccat cggatatccc taagaatacc
      421 gtggtggcga taaacaggat atagttaatc gccgtaaagg cggcgactcc atcctctcct
      481 aaatatcgca tcatcgttat attgaacaaa aaaatcgtga ttccggcaga tagctcggat
      541 attccttccg aagagccatt gtataacgca ttccagacca aaggccaacg gaaacgtcct
      601 ctttgtaccg ctacgacttg ccctcgctgg aacatccggg gaatattgaa cagcgctccc
      661 aaggtaaagg ccaagcctgt agccaatccc gcccccttaa tccctaaacc cattaccggg
      721 ataaacaaaa gatccagacc gatattaatc aacaccgtac ttcccattac gatcatggca
      781 taaagcggat gccccatcgc cttaatcata taatctccta agaacatcaa tgataataaa
      841 gggaaaaacg ggacaaggga acgaatatag tccacggctc ccgtaaccaa tacgtcattc
      901 gcacctaaca tacgggcgat atctccggcg aatatataaa tcaacccgct aatcaaaacg
      961 gatattcctc caagaaacaa gaacgaggta gttatagcgt tattcgcctc ttgccgatcc
     1021 gaacgtccga ggtttatacc gatcaaggtc tgacacccta ctcctatcac gatagacaaa
     1081 gccgtcatca aactatagca aggtaagatc agattcacgc tggccaaagc gttcgccccg
     1141 acaaaccgcc ctaatatcac accatcgatc accgactgaa tcccgaggaa taatagaccg
     1201 gctactcccg gtatcgtata tttcagaaat agtcttgaaa tcttttgggt tagtaaacca
     1261 cgctccaact cttggcgatg gatcgccttt tctccactca ttttcatatt atccacttca
     1321 cgtttttaac gacgcgaagg tatggctatt gaaaacaaga aaaattaccc tatgataaat
     1381 aatgactttt ccctattttt ttacggaagc acggatacgg ctcaatgact gtggggttat
     1441 ctgtaaatag gaggcgatat gtttcaaggg tagtttcaag atcaagtccg gacgggtttt
     1501 cagcaatgac tcatattgtt cacgagcttc catccaacta tcgtttataa aatagttctc
     1561 atattcccga agatagtaat cttgtatttt caacccccaa ttggccaact caagggagct
     1621 ccggcatagg taatccaatt tcgttttcgg tattctcaat aatgtcgtat tctccaccat
     1681 ttgaacatta taggcggaga tattccgata aacaaaattg atcacctcgc tatctgaggc
     1741 gaaccataac gagatatctt tcccctcacg ctccacgaaa gcccggacca atccggtttt
     1801 cacgaaccaa acgaacggat ctctttctcc ctcccgaatc gataattctc ccttagcaaa
     1861 agaaacctct ttcatttctt ccaacagctg ccccacgatc tcatctgata aaggagacac
     1921 ctgccttaat tgttctacga actgatccat aatcattcat ttatcttata tccgtaaaga
     1981 tataaaaaaa gtgcgatccc aaaaacaaag gtaattttga aggtttgcgg attccagtga
     2041 ttttacgtaa ttttgcgccg ctaaatcaaa gaagaggtat gagctgtaaa ttcgaatatt
     2101 atttttttac gactaaaagc atcttgttcg tccattggac tacgagaggc tctaccgtat
     2161 ccgcacccta ttccttctaa tttatcttta cattttcatt taaaacaact ctatcgtata
     2221 tccggcatat acgatcaagg atttttacac catcattaat aacagaacaa tacatatgta
     2281 caatagaata gcgggttaca aacaatatta taaatcctta gtaatgctag gggtacctat
     2341 catcattgga caattggggg ctatcatcac cggattggca gacaccatca tggtgggaca
     2401 acacagtacg gaggaactag cggcggcatc gttcgtcaat aatgtaataa acgcatttat
     2461 cataatggga accggattct cctataatct taccccgctg atcggacaga atttagcgat
     2521 gaataaaaag atcgtgatcg gaggctggct caaaaacagt ctggttgcca atatgactac
     2581 caccttatta ttgatagccg tcttactggg gatttaccta aacctagact ctttaggcca
     2641 acccgaagaa ctcttgccat tgataagacc ttatttcgca gtctcattag tctcgatcct
     2701 attcgtaatg ctttataatt cattccgtca attcgtggaa ggcatagcca acccatccat
     2761 atccatgtgg gtcctattga cagggaatct gctgaatatc atcggcaact atatcctcat
     2821 ttacggaaaa tgcggaatgc cggaactcgg actgctcggg gcaggtataa gcacctttat
     2881 ctcgcgtatc atcatgctat tgcttttcat cgccgtattc atgctgcgaa ccgactataa
     2941 gccttaccgg aaaggtttca cccatattcg tatcaataag caaagttgga gaaggctgaa
     3001 ttccataggc tggccgatca gtctgcaaca aggcttggaa gcgggaacat tctgcgtcac
     3061 cgccatcatg gtgggttggc tgggtagcct tgagcttgcc gcccatcaaa tagccattac
     3121 catatcaacg atcagtttta ccatctattt aggtcttgga gccgccgtag cgattcgtac
     3181 cagttattat aaaggggcga acgactggta tatggtgcgt aagatcacca ttgccgggct
     3241 tcatctgggg cttattgtcg tttgtattgt ctgcaccacc ttattcatga cccaatcctg
     3301 gcttggatta atatttacgg ataatcttca tgtcaacgca atcgtgaaga cactactccc
     3361 catattgatg ctctatcaaa taggagacag cgcacaaatc attttagcga actccttacg
     3421 agggctagcc gacgtgaaag cgattatgtg gatctcgttt ctcgcttatt tcatcatagc
     3481 catacctgcc ggatatctat tgggattcac attccattgg ggtatcgccg ggatttggat
     3541 ggcttaccca ttaggcttct tatgctctgt atgcctgctg ggataccggg cgaaaatgca
     3601 ggtaaaatcg catctcgcct aatccgatca agccttacga ttgatccggg agaaactaat
     3661 aaccgccccg atcaaggcca acacacttcc cagccataac gccgcgggca tgctatggcc
     3721 gggaaataac ttaaacatca aggctaccag cgaagccccg caagtttgtc ccagcaaacg
     3781 ggccgtaccc aacatgccac tagcccctcc actcctactt tccggagcgg ccccgatcat
     3841 gaggctattg ttaggagtct ggaacaaccc gaagccacaa ccgcaaagcg ccatgcgcca
     3901 gataatatcc agatcggaag gatgcgccgg taattccgcc aacgagaaca accctcccga
     3961 gaagataatc aacccgatac cactcaagac cccggcattc attttctccg acaagatccc
     4021 ggccaaaggg gcgcacacca ttgtcgccaa aggccaagga gtcaataata agccggtcgc
     4081 cacctcatcg cgtcccagta cccgctgcaa gaaaaacggg aaagagacca tagccagcat
     4141 ctgagcgatg aaagaaaaca cagacgtaat gatagaaagg gtaaaaagag gaatacgcag
     4201 caagtctatc ggcaataatg gatatgcctg ccgttcctct ctccggatat agaaataccc
     4261 acagaacaat acgataacaa tcgccgctat tatcaatgag atatgtacat catgcgtgaa
     4321 cgcctcgata atcgctatca ccaaaccgaa tgtcaatgcg ttcatgagtg ccgccgtaac
     4381 atcaaactta cgtccgacag ccttcaccgg attttgcggc aagaacttaa agctcaatat
     4441 caaagcggta atacctatcg ggatatttat agcgaacaac caaggccaat tccccacgga
     4501 caatatacca gcggctatcg taggaccagc ggcggccgat acggatacca ccaaggcatt
     4561 aatccccata cctcgcccca gaaaacgttt gggataaata atacggatca aggccgtatt
     4621 cacgctcgct atggcagcgg cgccaaaacc ttgtagcgta cgggcgataa tcagcgtaaa
     4681 caaggaatcg gataaagcgc aggccaaaga ggtacagcta aataacagca acccgatcgt
     4741 atacaccttc cgataccccc agatctctcc catcgacgat aacgacagca aagaaatcgt
     4801 gatcgccaac tgataagcgt tcaccaccca tatagaagca gacggactcg tatggagatc
     4861 gccggcaatc gtaggtaaag ccacgtttgc gatcgcccca tccaacaccg acacggtaac
     4921 accaagccca atcgctagga tcgcccaata acggctaggg attggcaagc catccgggat
     4981 attccctccc gtctgaccat ttatattcgt tatttcttta tccatacggt atatgaaaca
     5041 gaaataggat gtatctggtt taggaagtat cgaccagatc gagtatcttt gcccgtataa
     5101 atggacatga catggcaaaa caaggcacta tactagttgt ggatgataat aaaggtatcc
     5161 tgaccgccgt acaaatgctg ttaggaactt gcttcgagaa ggttatcacc atctctaccc
     5221 cgaacaagat aaaaaacacg ctgcacgacg agaacgtgga tgtcgtattg ctcgacatga
     5281 atttcagcgc cggtataaac agcggcaacg aggggttgtt ctggctctcc gagatcaaga
     5341 aggcttatcc ctcgatacaa gtcgttctct ttaccgccta cgccgacatc gatctggcgg
     5401 tacgaggaat caaggaaggg gctaccgatt tcgtggtaaa gccttgggac aacgctaaat
     5461 tattggaaac cttgcaagcc gcttaccaaa tccgctcggc caatcataaa ggcggtgtcg
     5521 gcaacaagca gttggtatcc aaggaaagcg gtatgttctg gggagacagc aacgccatgc
     5581 agcaactacg gatgctgata gagaaagtag ccaagacaga cgccaatata ttaatcacgg
     5641 gagagaacgg aaccggtaag gaaatgctgg cccgggaaat acacctgcta tccccccgca
     5701 aggatgaggc catggtaccg gtggatatgg gcgctatcac ggagacgctg ttcgagagcg
     5761 agctgttcgg acacgtaaaa ggggccttca ccgacgcccg gacggatcgc cccggtaagt
     5821 tcgaggtagc gaacaacgga agcttgttcc tcgacgagat cgggaacctg tcttatcatc
     5881 tgcaagccaa attactgacc gccttgcaac gccgtagcat cgtacgggta ggcagcaata
     5941 ccccgatccc catcaatatc cgcctgatct gcgccacgaa ccgggacttg caggagatgg
     6001 tacagaaaga gcaattccgc gaggacttgc tgtatcgtat caatacgata cacgtagaga
     6061 tcccgccctt gagggagcgg ccggaggata tcgtaccgct taccgagata ttcatcacga
     6121 aatataccaa catctacggt aaaaagccca tggccctcac cgacgacgcc aaggaaaagc
     6181 tgaaagccca accttggctg ggtaatatcc gcgaactgga acataccgtg gagaaagcga
     6241 ttatcatcgc cgacggtgat actttagatg gcggcaattt cgatttcccc cgtaagcggg
     6301 aggcgcccgt caagaatgac atcactacgc tcgaggaaat ggagtatact atgatcaagg
     6361 ccgccatgga taaattcggc ggcaatctct cgctcgtggc gaaccagttg ggtatctcac
     6421 ggcaaacgct ttataataag atcaagcggt atgaacttta aaggcattta ttacagcctc
     6481 accttccgcc tcgccctcgc tatcgggctg acggcggcac tcacctactt ggccttggcg
     6541 gaagaatggg ggtggttcct gttcttaggc gtcggatggc tggcgacctt gcggggcatc
     6601 agccttttgt tcaagcggaa cgcgcaaaag gtagccttca tgttcgacgc gatcgacaat
     6661 agcgattacg ctttcaagta cgctacccgg gggcgctcct ccaacgacaa gctggttagc
     6721 gactccttaa accgcatcac ccaaatactt tttcaagcga aagccgaggc gatccagaaa
     6781 gagaaatatt acgagttgat catgaaccaa gtgaatacgg gtatcatcgt agaagatgat
     6841 aagggcaata ttttccagac aaacaacgag gccttgcgac tgctgggatt gacagtcttt
     6901 acccatgccc gccagctcgg acgtatcgac gagaatctag agcgcctcat cagcgacgtt
     6961 cgtcccggcg agaaacatca gatctccttt atcaacgagc ggggtacggt acatctctcg
     7021 gtccgtgtct ccgagatgac gctccaagag aaacacgtcc gcatcatcgc gatcaatgat
     7081 atcaacagcg agctggacga taaggagatc gagtcatgga tacgactgac acgggtcttg
     7141 acccatgaga tcatgaactc cgtcacccct atcacctcct tgagcgacac cttgctttcc
     7201 ctccaccaga atgtcgacga ggagatacgg ggcggcttgg aggtaatcag ctctaccgga
     7261 aagagcttga tcgcgttcgt cgagtcttac cgtaagttta cgcatatacc gacgcctcag
     7321 ccctctttat tctacgtcaa caaattcgcc gaacggctca cgcggttggc ccgccaccac
     7381 aataattacc cgaacataac cattcgcatc gacgtggaac cgaaggactt gatcgtctac
     7441 gccgacgaga acctgatcac gcaagtagtc ttgaacctct tgaagaacgc catgcaagcg
     7501 atcgggcacg agcaagaaaa cgggcttatc ttgttcaagg cgtattgcga ccccaacgag
     7561 gccgttatcc tagaagtgac gaacaacggc cccatcatcc cccccgagga agccgagcat
     7621 atattcgtgc cgttctttac cacgaaagaa ggcggaagcg gtatcgggct gtccatctca
     7681 cgacagataa tgcgcttgtc cggcggcagc atcgcattga gaagcaatcc ggcccagcgg
     7741 cagactacct tcgtgttgac attcccgtag ctcgtttatc gtatccgcat aaacgcggac
     7801 acgcggccgg gcggatacgc ggacacacaa gcccggatac acgggcgcga ccgtacgggt
     7861 acacccgcgt atccgggcag ctacatcttt gtatccgagt agttacatct ttgtagccgt
     7921 acggatacgg acagacagcc gggcagctac aagaggacag ccgtacggat acccgccatc
     7981 ggccgtacga acgtatttcc ggccaccgtt gggtaacaac gaaactattc gtatctttac
     8041 actgtttttt aaatttaaaa gtatctatac aaacatgaac ttactagaca aactgaagat
     8101 caaccaccgc ccccgctccg gggcattgga tttgctaaaa tatatcggcc ccggattact
     8161 tgtcaccgta ggctttatcg atcccggaaa ctgggcgacg aatcttgcgg caggctccga
     8221 gttcggctac gccctcctgt gggtcgtcac cttctcgtcc gtcatgctga tcattatcca
     8281 gcacaacgtg gcccacctcg gtatcgtgac cggcctctgc ctctcagagg cgaccaacaa
     8341 atacatgccc cgcgtgctaa gccgcccgat cctaggatcg gccatgctcg ccagcgtatc
     8401 cacctccctc gccgagatac tcggtggagc catcgccctc cggatgctgt tcggtatgcc
     8461 gatcaaggcg ggagcggtga tcgtcaccat cgtatgcctc gccatgctat tcagtaatac
     8521 atatagtaag accgaacgct ggatcatcac gttcgtgtcc attatcgggc tctcgttcct
     8581 atacgagctg gcgttggtcg acgtagactg ggggcaggcc gtggtaggct gggtgaaacc
     8641 caccttcccc gagaactcca tgctgatcat catgagcgta ctgggagccg tcgtgatgcc
     8701 tcacaacctg ttcctgcact cggaggtgat acagagccgg gaatggaacc tagaagacga
     8761 gtcggtcatc aagaaacaac tgaagtacga gttctacgac acgctcctgt ccatggtgat
     8821 cggctgggcg atcaactcgg cgatgatcat cttggccgcc tctaccttct tcaagcaaaa
     8881 catcgccgta gacgagctgg accaagcgca acagttattg gtacccctcg taggaaataa
     8941 cgccggggtg attttcgccg ccgccctatt actggcaggt atctcctcga ccatcacatc
     9001 cggtatcgcc ggggcttcca tcttcgccgg attctatggc gaggcgtaca atcataccga
     9061 cctccactca aagctgggag tcctgctatc gttcgtcccc gccttggcca tcatattcct
     9121 gatcggcgat ccgttcaagg gattgatcct gtcgcagatg ttgttgagcg tgcaattgcc
     9181 gatcacggtc ttcacgcaag tgtacctcac ttccagcaag aaggtcatgg gtgtctacgc
     9241 gaacagccgc tctacgacca tcatcctctt gctgttggga acgatggtaa ccgtcctaaa
     9301 tatagccctg ctcatcagcc tattttaaaa agaaatcgct acctttgccc cattcgaaga
     9361 aaaactatca atttttaagt atgagcgata tcaatacaaa cgaagaagaa ggcaagaaga
     9421 acctgaattt cattgaggca gccgtagaga aagatttagc ggaaggcaag aacggaggac
     9481 gtgtacaaac ccgtttcccg cccgagccca acggatacct tcacatcggc cacgcgaagg
     9541 ccatttgcct agatttcggc atcgctgaac gccatggcgg tatctgcaac ctccgtttcg
     9601 acgacacgaa cccgacgaag gaggatgagg aatacgtgga ggcgatcaag gaggatatcc
     9661 aatggctggg atatcagtgg ggaaatattt attacgcgtc cgactacttc cagcaattgt
     9721 gggatttcgc gatccgcctc attgaggaag gtaaagcata tattgacgag cagacatccg
     9781 aacaaatagc ccagcaaaag ggcacgccta cacaaccggg catcgagagc ccgtatcgca
     9841 accgtccgat cgaggaaagc ctagctctct tcaagaagat gaacacgggt gagatagcgg
     9901 aaggtgccat ggtacttcgc gcgaagatcg acatggcaaa cccgaacatg cacttccgcg
     9961 atccgatcat ctatcgggtg gttaaccatc cgcaccatcg tacgggcacg acgtggaaag
    10021 cgtatccgat gtacgacttc gcccacggac agagcgattt cttcgagggc gtgacgcatt
    10081 ccttgtgtac cttggagttt gtcgtacacc gtcctctgta tgatttgttt atcgactggc
    10141 tgaaggaagg cgaggacttg aacgacaacc gcccccgaca gactgagttc aacaaattga
    10201 acctaagcta cacgctgatg agcaagcgta acctgcttac attggtaaaa gagaacttgg
    10261 taaacggctg ggatgatccc cgtatgccga ccatctgcgg tttccgacgc cggggttact
    10321 ctccggagtc tatccgtaag ttcatcgaca agatcggtta tacgacttac gacgccctga
    10381 acgagttcgc cttgctggaa agcgccgtac gcgaggatct gaatgcccgc gccatccgtg
    10441 tatccgccgt gatcaatccg gtgaaactga ttatcaccaa ctatccggaa ggacaggtcg
    10501 aggagctgga agcgatcaac aacccggaag atccggaggc cggcagccat acgatcgagt
    10561 tcagccgtga gttgtggatg gaacgtgagg acttcatgga agatgctccc aagaaatatt
    10621 tccggatgac accgggacag gaagttcgtc tgaagaacgc ttatatcgta aaatgtacgg
    10681 gctgcaagaa agacgagaac ggtgagatta ccgaggtata ttgcgaatac gatccgaata
    10741 cccgcagcgg tatgccggac gctaaccgta aagtaaaagg taccttgcac tgggtaagct
    10801 gcgcccattg ccaaaaagcg gaagtacgct tatacgaccg cctttggaag gtggagaacc
    10861 cccgggacga attggccgct atccgggagg agaagaattg ctccccgcta gaggcgatga
    10921 aggaaatcat caacccgaac tccttggaga tccggaaaaa ctgttacgta gagaagttcg
    10981 tggctacctt gcccaagctt tcctaccttc aattccagcg tatcggctat ttcaacatag
    11041 atagcgaatc cacccccgac aacttggtat tcaaccgtac cgtagggcta aaggacacgt
    11101 ggagcaagat taataaataa agaatagtaa atgaaaaaag acgatatctc acgcttgtta
    11161 caacattatc tttcagcgaa ggaagagggt aaggagcctt atttcgacgc tgatcaaatc
    11221 gatgaaatgt tggacagctt tgaagattcg aacgattata cttactttga tgaagtctta
    11281 gccctcgggc taaagcttca tcccggtaat tccgccttgc aaatcaagaa aggcaggcaa
    11341 ttcgcatata acgaggatta tgagagcgct ctcgctctgc tcgagaatat agcggagact
    11401 gataaccaag atctggatat gttaaaaatg gaatgctatt gctcgctcaa ccaatatccc
    11461 aaggttctgg agatcacgga agagttgatc actagggatt gtgactattt ggaggaagtc
    11521 ttcgagtaca tctcccccat cttgaatgat ttagacatga acaaagaggc ccgcgatttc
    11581 gtggaccgtg gcttggcttt atttccggat aacttgatcc ttaagaatga gctttgctac
    11641 atcctcgaga cggaaggaga cgttccccgg gcgatcgagt tatgtaatga gctaatcgat
    11701 aagaatcctt tctcatacga gtattggttt acgctgggaa ggctacattc catggttggc
    11761 gattacgaga aagcgatcga ggctttcgac ttcgccttga cgtgtgatga ttccgatacg
    11821 gaactgaaaa tattgaaagc gtactgcctg tatatgaacg agagctatga gaaggcgatc
    11881 gaggaatatc aagaaatcga gggtgatgag gaggtgatgc gccgtatctc tccactcatg
    11941 gcggaatgtt atatgaagct ggagcaatat gagaaggctt accaactgct ttccacgatc
    12001 ataaacgatc cggatatgga ggatgggccg accaattata tcaattatat ccgttgttgt
    12061 accgagactg agcgcgacaa cgaggcttcc atcatgttat tcaaggcggc gcaattgtat
    12121 ccgaacaatg tccgtctcct ttctctttta gcgctttgct tgcttgatag cgggaaaaag
    12181 gaggaggcta tcgctattac gaataagata ttcaagatca tcgataagaa aagtatcaat
    12241 ccggaaactc aagaagaatg caacagcctg cttcatgccg gacaatattt gctttctaag
    12301 ggagatatag ataaggcgat ctcttattac aagaaagtcc ttcaaatcaa cccgaagact
    12361 ccaatgattc atatccattt ggctatggct tatctggata accgtgatat ggaaaatttc
    12421 atggagcata tcggccaaat atccggagat gatcttcttt atttgcttcg taaagtggga
    12481 ccagaagtat ttgcggactt taccatcgat tccgataaag agaagaaaca tatccaaccc
    12541 gaggatctgg taaaagagtt tttaaagaat aaagataaca gtaattagac aattaataat
    12601 gtaatatgcc taacaaacga aatctcaagg actacggttt tttagtatta aaaggtatgg
    12661 gtatgggagc ggcggatgtc gttcccggcg tgtcgggagg aacgatcgcc tttatcgtag
    12721 gtatctacga agaactgatc gactctatca aaagtattaa cgggacgaca ttgaaacaat
    12781 tattcacggg gaaaatagcg gccttctgga aagggatcaa cgctaatttc ttgctttcta
    12841 tcgtgggtgg tattggtatt agtatattct ccctagcgaa gatcattacg tatctcttgg
    12901 tgtatcatcc gatcttggta tggtcttttt tctttggttt ggtgctggcc tccacttggt
    12961 tcgtctctaa ggatatcaag caatggaact ggaagacgat cttgagtttt gttgtcgggg
    13021 cagtgatcgc tttttatatc accgtggcga ctcccgccga gactccgagt aatttactct
    13081 ttatcttcct ctgtggggct atcgctattt gcgccatgat cttgccgggt atctcgggta
    13141 gctttatctt agtgttgctc ggaaaatact tctatatcat ggaggcggtc aagacgttta
    13201 acgttcccgt tatgttggtg tttatagcgg gtgcggctat tggtatcacg acgttctccc
    13261 gcgtgttgtc attcgccctt cgtaaattcc atgatataac gatcgccgta ttggccggat
    13321 tcatgttggg ttcgcttaac aaggtatggc cttggaaaga aacgatcgag acctatgtgg
    13381 atagccatgg catgaccaag ccgttggttg aggcgaatat cgctccgaat cagtttgttt
    13441 gggaggccgt cggattgatg atcttaggtt tcgggatcgt atatttccta gaaaagctct
    13501 cacaaaaaag cgctaaggcg taacccaata ttacaatggg cattataagg tgattagaat
    13561 gcccattgta accttcttat aatgcccatt caaaggtggc tacaatgccc attcttatct
    13621 actaatcatt tctatcatcg cacatcgtac ttttccaata agcgaaaccc tccccatacc
    13681 agtaaggcga taaagaaaaa cgtggtcagc gcatacaggc caataagcgc aagacgttct
    13741 tttaagggaa cgcttctttc ttgatatcga ggcgcttctt ttatatcaaa cgactttcgg
    13801 ctggtagaga catcctcata aggattatac caatgtgggc tttccgggtc ctcggcgtct
    13861 ttttgcttga accatgcgag gaacgtaagt tggaaggcct gtaaatcacg ccaatttttc
    13921 tggaatcgta gatggcctcc tcctaataga gcttccatcg cccgttcgta ttggacggtt
    13981 ggggacagga gggtcaatcg acggactccc tcgaactggc ggatcaggca ttcgtagtaa
    14041 tcccgatagg atttctccct tacttccttc tttttcataa ataaagtagc acgacgctca
    14101 tgatagggat aaaacgggtc gtctctctct tgtgccatgc ttccgggagg ggcctctttt
    14161 gtcaaccggc tttcctcttc ctctactttt tgagcgatgt ctcgtaataa agggctcgga
    14221 tagaggacat cgccccagaa tgtggcgcta ttcgggataa ttatggttcc aaacagccaa
    14281 aaggatacgc acatgagtag acttacactc gaatgcctcg tcatgacgga ggcgaacaat
    14341 ccaaaacagg tacataatga gatcagcaaa aagctgattc cgataaatcc gagtatctta
    14401 taaattaaag agggcgtata gatggacggt agcatattac ctaaggctaa taatcccacg
    14461 aatatacctc ctagcaataa taacatgaca acggatatat gcgagagaat cttactgatc
    14521 caatagttcc tccgggaaat gggataggat aacaaataac ctaatacctt atcccgtttc
    14581 tctccacata tcgaatcata agagaataac agggcgataa agctaatgaa tatcgagacg
    14641 ataaatgtcc agtccaccga gcttttcgca tccagtaaag ggtttagcat cccttgctct
    14701 atctccaagc ctcccgcgtt ccatacatta tattgaatgg tgtttaccat ttcctcctct
    14761 ttacagctat acaagaagcc gtcggtgcgg ggagagtaac ggaatatccg taggctattc
    14821 gcatagtttg tcaagttttc gctcaactcc cggtctctcc gttcctcgtc ttcctccaat
    14881 tgccggtaag tagcctgctg ttccgtatag aatgagacaa acaagcgact tcctccggcg
    14941 aatagcagcc cgataagcac gaacgatacc cggaaacgca aactacgcga caggcggctc
    15001 acctcatggc ggtataatag aaagctatcg taaatcatat cttctaaaaa tgtaaatagc
    15061 actcgctaaa agcgcaataa acaggatgaa caaaaggatt aaagaccgcg cacctctctg
    15121 cgcccgctgc caaccggata attcccgcag gctgaactga gggatatccc gaacgtctac
    15181 gggcgaatag ttcgcgtcgg catactgttg ctcggcatct ttcatgatcc tctcaaaagc
    15241 gggaggatcg ttcttctgaa gtttctcggc ctgtcgttcg aaagcctccc attcctcttg
    15301 cggcagaaac tcatcctccc ggcaaggagt cacgtaggaa ggcgaataga atagctctcg
    15361 atccgtcaag taacggatga actgttcgcg atagtttcgt gcatcgctca tataagacag
    15421 gagcgcatcg gcatcggtat tgcccagccg ggccatcaaa cggatataag tagccgatgg
    15481 agagagtaga ttcaagatat cttgccactt tcgctgagca gacaatgtac acaagtattc
    15541 ctcatccagc ttccagagtc gctccgcatg atctatccgt atattagcgt ctacaaccgc
    15601 catccggcgg gtatgctcca gcaccaaccg ggagcctccc cgaatatctt tcgtaccttc
    15661 tccatcctct acatcaaata aataccgcag ggattgaagc cccaaggaat cccgtaactc
    15721 cctccatcgc ttatcatact cacttctcat cgaccagaaa agttccactt tcttgttctc
    15781 cacctgttta taagagggca aggccaccat gctacgggaa gcatacgagg acaaggccgg
    15841 gatcacgaac aggaatgtca gccaactgag catacagagt acgatcgagg tgaccgaacg
    15901 ggccgtcaac gacgataccc atataccgaa cgagccaaag aaagccaaat agacaaacga
    15961 agccaacaac atccatccga tccccaccca ctcgctaccc gagaatcgta ctccaccttc
    16021 cagcaccacg aagcccagcc ccatcaagaa gcaagctagc aggatcggca aaacagttaa
    16081 taccaccccc agccacttcc ccaccaagaa gctataccgg ctcaccgacg aggagaaaat
    16141 gaaacgcaac gtcccctcct ccctttccct cgtcaccgtg tcataagaaa agaccaaagc
    16201 gaggagcgag atcataatac tcaataccgc agagaaatcc aacgggggaa acactttcat
    16261 gaacgggctg ttttgcgccc agttaaattg aaacggcagg aacgggatct cccacagagt
    16321 gataagaacg gtatacccta tgttattcgt gatcccccgg ctgagcaaac tcaaaggctc
    16381 cggctcccgg acgagcttag gatgcacctt cgaccatacc aagcaggaac ttatctcctc
    16441 ctcggcttgc ctcgcctctg cctcgcatac ctctttttgt atctggtaat cgcctatacc
    16501 gaccatcatc gtgaagggta cgataaccaa gcaaagcaac aggcctatgg cgaaacgtgc
    16561 cgaccggatg ttcagccgaa actccttcca tgcgaatatc cagatatttc tcataagacc
    16621 gcctcctgca tatagtccag atagatacgt tccagatcat cgcgcaggaa ctcatcccgg
    16681 gagcggacca tgaccagacg cccatccttc atgatcccta ctcgatccgc caaggaacgg
    16741 gcacggaaca ggtcgtgggt acaaatcagt atcgattttc cttccaagcg gaggtggtgc
    16801 aagagttgca tcaactcggc ggtgctccgg ggatcaaggc cggaggtagg ctcatccatc
    16861 accatattgt cggcgtcttt caacaagagg gcggcgatct ctactttttg ccgcattccc
    16921 ttggagaagg tcttcaactt acgctcgaag ctttcttccg gcaggccgac acgacgcatc
    16981 gcttgataat agtctctccg atccaagcgt ttcccggtaa ggcgtgtgaa gaagtccaag
    17041 ttctcccggg cggtaaagtc tccgtacaac atgacgttct cggagacata ggcgatatga
    17101 cggcgtgtct ccgccggatt ggaacggacc tctaccccgt tcaccaaggc ccgcccggaa
    17161 gtgggacgga tgaaatcgag gaagaggttc aaggtcgtac tcttccccgc cccgttggcc
    17221 cccaaaagaa agaagatctc tcccggctcg atccggaggt tcaaggcatc cagagccaga
    17281 tgcccatcct catatcgttt cgttaaatca atcgcttcta acatgaaaca aagataatca
    17341 taatctgttg ataacctcat tggccgcacc ggaacctttg tacttactac gggtggcgtt
    17401 gaaacgatac gtaacggtca ggcgcacttg gcgactatcc ggattactcc atttcgtcat
    17461 actgcggtcc gccgcataca tcacgaaaga ataacgttgc gtagcgaaaa tatcgaagcc
    17521 ttgcaagttc aatgtcaacg cctcgtcttt caagaacgac ttacgtaacc ccacataaac
    17581 ccctcccgtt cgcttactta aactttgcat actatcgcca tctgtcgaaa cacgaccatc
    17641 caacgagaat atccatcctt taggcaaacg aaacgagttg tttaaactaa agccataagt
    17701 aggtttatta aaggatcgca tctcccccat cgtaaaagcc tcaaagaaag gtttgctcac
    17761 gcttaggtaa agggaaggtt cccagaaatt aaacttaggg gaaaaagaga cggaagcgtt
    17821 caaatattgc gccttcggat agttttcttg ggagaagacc gtaatgaccg gatccggctc
    17881 gtacgccttc atcataaacg acgaaacatc ttttatatat tggtaattca atgaggcttg
    17941 gataaattta tagccaaatt gataagtcaa gtcgtgattg aaagagggtt tcaatagcgg
    18001 attaccgccc tcgtaagtga aacgatcgtc gtactgcaag tcactccgca attgataaaa
    18061 cgaagggcga cttgtctttg ccgtataact taacgacatc tgggtctttc ctatcggcat
    18121 ggaaagagcg acattcggga agacattatc atacagacgg ctttgttccg gaaggaaaat
    18181 acctttatca taataatcaa agtcaacatg ctcataacgc aaaccgatct cagcgcttaa
    18241 tttctgccaa gtcaaggcat aactgataaa agcggcggca ttctgctccc gtatcttgct
    18301 atcggtagcg ggcaggatgc tttgtggatt gtcgaaacgg tccgtacgat gtacataact
    18361 gtattcccct ccccatttca attctcccac ggcgatcggg taagtcatca ctaatttaac
    18421 ggcatacaaa cgattgcgag tccggttact ggttgttacc aagcgatcgt catccatctc
    18481 gctattctca ttagcaaaca tacggttctc cgaagatccg gttaaccagt ccgcattaaa
    18541 actaatggtt agtttatcat taaacctccc ttcataataa gcgttcacct tgtgttgatt
    18601 tacgtccgtt tccatgcggg tttggtaatg caatacatca tataccgttt tatttgcgta
    18661 catcgtgtta tccgatacga aatcacctcc cgagttaaaa cccttatttc cttcatacgt
    18721 agcgccgaag gaatgatgct cattcacctc gtaattcgca cccaactgac catataccga
    18781 acgggaagac tggtccactg tcgtttccgc tttctgttcc cacagcgtgt ccacttgaat
    18841 atagctactt gtccgttgcc tcgtttgggc ttgccacaag gaatagttaa ccatcccaaa
    18901 caaatccaat ccgttcttac gatagttcaa gttcaattga tccgtgttac tcgtcttatg
    18961 gctttgggaa acattactcc ggacattgac acccaatccc tcgcccgcat gccgaaccgt
    19021 acgaattttc aataccgcct tcaccgtagc gtcatattcc gcacccgggt tctggatcag
    19081 ttccaccttg gagatatcct tcgagcttag gcgttccaat tccgaattat cacgaaccaa
    19141 acggttatta atgtagatca aaggctctcc cttgccgaac acggtatatt tcccgtccga
    19201 gctttccaag ccggggatat gcgagagcac gtcattcgcc gtaccgaccg tactcagcaa
    19261 agtctcctga atgttcgtca ccaagctact tccctttagt tggtaagtag gcagtttacc
    19321 ggtcacgacc gcctcgccca aggcgatggc atccggttcc agacggatcg ttcccacatc
    19381 ccccgccttc gggcactcca gacaaatatc cttatatccg atataagata cccgcaagat
    19441 ataacactgc tctttcaagc cttccaacac gaactcaccc gactcctcgc taaccgtccc
    19501 ttttacgaac gcggaatctt ccggattcaa taacaccaca ttggcgaaac caacaggcgc
    19561 ctctttatca tctactaact tacctaggaa agactgtgca ttgacgcttc ccccaaagat
    19621 cgctataagt atagcgagta aaataacagc tttctttctc atattcttat tctttttatc
    19681 gtatctaatc aagtctgcga tcactatcca ctaagcattg ataaccaaca aactacagtt
    19741 tcttaaaatt ccttactagg aaaacttttg tttcttcctg tgaaaacttt tgtttctcta
    19801 taggaaaact ttagtttcat tgaaggaaaa acttagtttc tagtaaggaa aaacatagtc
    19861 cctcctatgg aaactaaatg ggtatcggta aacttttacc caaatatacc agagatcatc
    19921 cctctttacc ctatagaata caaacgccgt gccaaagcat ataactcact aacaaacaat
    19981 attatacaca aacagcgaat attccatctt tgggtaacgg gtaatatcct tactcaaaac
    20041 gggtaaattc ttactcaaaa agagtacatt tgcccatcct aatatccgag aagcatgtta
    20101 tccttattca aacgacacac aaatacaccg cagcccgaac tcagcaagat gctttccgag
    20161 ttcaaccgtt ccttgatgct tatcgcagat aagtccctac tgatcaataa ttttatctcc
    20221 aagatcagac agatatgccc tgtagaaatc attcatcttt ttctattaga tgagaatacg
    20281 ggaaagtata aaccgcaaga cggcccgtta tcctcttccc tctctttcaa tggaaaagat
    20341 aaactgatca gttggctatt cgtgaacgag cgctcgcttc tgctctccca aaatcccgat
    20401 atagcggatt acttcacggc cgaggagcgg gagaagctgg agcaactcca agcggagctc
    20461 atttacccgc tcaaagtgat gaataaggtg agcggcgtga ttatgctggg aaagaagaca
    20521 gatcgcaccg gttttaccga gaatgagctg gggcttctct ccctcttgtt caaccaagcg
    20581 gcattcgcca tcgaacatgc ctccctttat gagatccaat ccgaacgaat caagaagatg
    20641 taccggaccg accggctcgc cactttaggg gaactggccg ccggagccgc ccacgagatc
    20701 cgtaacccgc tgaccgccat tcgtagcacg atccaatact taagcaagga tttctcggcc
    20761 gatcccgtga aatcggagat ggccacggaa ctcatctccg aggtggagcg tatcaacaag
    20821 atcgtgcaag gcctgctctc tttcgcccgt ccatccgcct tgaattcatc ggaagtcaat
    20881 ctggagcaat tgatcaacca gacattgcta ctcgtccata atacgctgaa gaagcaacag
    20941 gtcgaggtgg aatttgaata tttccatgag aataccgcct tgcaagcgga tgccgagcaa
    21001 ctcaaacaag tatttctcaa catcatcctc aacgcggtgg aggcgatgag ccagaatccc
    21061 ccggaacgct cacgtacatt aataattagt atagagaagg gagcatccat tgacgatcat
    21121 tcccattacc tgctcctctc cttcgaggac agcggaaaag gcatcggcga gaaagatctg
    21181 gatcacatct tcaatccctt cttcaccacc aaagacgagg ggactggttt aggactcgcc
    21241 atctgttacg gtatcatcaa ccgccacgag ggcgagatcg aggtacacag tactcccggc
    21301 aaaggcacat gtttcaccat caagttaccg caatatatag tatgaaagca aaaatagtag
    21361 tagccgacga cgagccgcgc atccgtgcga tgatcgccct gctcttgaaa gaagacggat
    21421 acgaggtaca aaccgccgcg aacggacaag aggccgtaga cgccctcctc tccttccgtc
    21481 ctgacgtgat cttgctagac cagcaaatgc cggtgcttac cggcgtggag gcattggaga
    21541 agatcaaacg gctatgcccg aaccaagtcg tcgtgttcat aaccgccttc ggttccgtct
    21601 ccttggcggt agatgccgta aagaaaggcg cttacgattt tattgagaag ccttttgaca
    21661 acgataagtt gctccttacc gtaagccgtg ccgtagagca ttgccggatg aaaggcgaga
    21721 tcaagcactt gaaaaacaag ttaggagata tgaacaccgg tatcatcggt gagaaaagcg
    21781 gactgaggca ggtcatgctc caagtgggac gggtggcgga aaccgacgct accgtcttga
    21841 tccacggaga gagtggaacc ggaaaggaac tgatcgcctg ggcgatacac gaccggagta
    21901 aacgcgtgag ccagcctttc gtggcgatca actgtggggc gatcccgctc accttgatgg
    21961 agagcgagct ttttgggcat gagaaaggcg cctttaccga tgccaaggaa acacaagccg
    22021 gcacgttcga gcgggcaaat ggcggtaccc tgttcctaga cgagatcggt gaactcccgc
    22081 tagacgccca agtaaaatta ctgcgtgtat tagaagaacg taagattacc cgcatcggag
    22141 gcaagaaagc gatccccgtc aatgtccgga tcgtggcggc tacgaaccgg aacttggaag
    22201 aagaagtaag actgggtaaa ttccgtctgg acctgctcta tcggttgaat gtcttcacca
    22261 tacagcttcc accccttagg gaacggaaag aggacatccc gttgctggcc gcatttttcc
    22321 ttcgcaaaca taattccttg ctcaatctct cgatcgagag catcactcct gaggctatgg
    22381 atcagttatg cgcctacgac tggcccggta acgtacggga tttagagaac gccgtacaaa
    22441 gcgccatgat actctgcgta aaccggcaaa tccatcccgg acatctgccc gcccgtatca
    22501 aaagctacca gatggagcga ctgatagctc ctcaggaagc ggaagaagac acctcgctcc
    22561 gtgatacgaa ctccttggcg gagaagaccc gcatcctgtc cgcgctgcaa aagcataact
    22621 ataaccgtac cctgaccgcc gaggctttaa atatcagtag aaagacgcta ttcaacaaaa
    22681 tgaaacgtta taatcttggc aacgagtaat tttttactaa ctttgatgcc tcaatagaaa
    22741 tgtgttacat ttagatttta aataaacaag tattatggcg aaaataaaag gagctgttgt
    22801 tgtaaacaca gagcgctgca agggatgtaa cctttgcgta gtagcctgcc cgtcggatgt
    22861 actggagttg cacccacgag aagtaaacaa caaggggtat cactatgtgt acatgaagaa
    22921 cccggacgca tgcatcggtt gcgctagttg cgggttagtt tgtccggacg gttgtctaac
    22981 gatctacaaa gtaaaaatat aaagttatat caagatatgg cagaagatat aaaattaatg
    23041 aagggtaacg aggccatcgc ccatgcggct atccgctatg gcgtggacgg ttacttcggc
    23101 tatccgatca ctccgcagtc ggagatattg gaaaccctta tggcagagat gccgtgggaa
    23161 aagaccggca tggtagtctt acaagcggag agcgaggtag ccgctattaa tatggtatac
    23221 ggcggagccg gttccggaaa gaaagtgatg acctcttctt ccagtccggg cgtgagcttg
    23281 aaacaagaag gtatctctta tatcgcagga gcggagcttc cttgtctgat cgtgaacgtt
    23341 atgcgtggcg gtcccggatt aggaacgatc cagccgagtc aggctgatta tttccagacc
    23401 gtgaaaggcg gtggtcatgg cgattaccgc ttgataacct tagctccctc ttccgtacag
    23461 gagatggccg atttcgtagg ccttggtttt gatctggctt tcaaatacaa taaccccgct
    23521 attatcttgg cggacggtat catcggacag atgatggaga aagtggttat gcctccctat
    23581 caaccccgcc gtaccgagga agagattatc gctcaatgtc cttgggccgt acaaggaaag
    23641 aagggaggac gcaaaggtaa cgtcatcact tccttggagc tagacccggc gaagatggaa
    23701 gagaacaata tccgtttcca agcgaaatat cgcaagatcg aggaaaacga ggttcgttac
    23761 gaggagttcc aatgtgagga cgctgattat ctattgatcg cattcggttc ttccgcccgt
    23821 atttgccaga aggtagttga gatcgcccgt gcggaaggta tcaagcttgg cttgttacgc
    23881 ccgatcacgt tatggccgtt cccgacaaaa gtgatcgccg cttatgcgga taaggtaaaa
    23941 ggtatgttat cggttgagtt gaacgccgga cagatggtag aggacgttcg cctagccgta
    24001 aatggtaagg tgaaggtaga gcactttggc cgattgggtg gaatcgtatt caccccggat
    24061 gaggtattga acgcgctgaa ggaaaaatta ttctgatccg tatgacacga ggaagtaaag
    24121 ctgacgagat attgacgctg gtttttatgc tactggccat agctgccgtg gtatgttact
    24181 tcgctgttag cgataaggcc gtattcttgt attgtggcgg ggcggcgatc gtattgcggc
    24241 tggtgcaata tgtcttaaga tatatacatt aataattaaa gattatggaa ctcaacgata
    24301 taattaaacc ggaaaatctg gtgtatgaaa agcccagatt gatgaatgaa aatcccatgc
    24361 actactgccc cggttgcagc cacggtgtga tacataagct aatcgccgag gttatagccg
    24421 atatgggtct ggaagataag acaatcggta tctcccccgt gggatgtgcc gtattcgcat
    24481 ataactactt ggatatcgat tggatcgagg cagcccacgg acgtgcgcca gccatcgctt
    24541 ccgccgttaa acgcttgaat ccggagaaga tggtattcac gtatcaagga gatggtgact
    24601 tggcggctat cggtacggcc gaaacgattc atgcagccaa ccgtggcgag aatatcgtga
    24661 tcgtattcgt aaataacgcg atctatggta tgaccggcgg acagatggct ccgactacac
    24721 tggaaggtat gcccacggct acctgtcctt acggacgcaa catcgccttg aacggttacc
    24781 cgctgaagat cggtgattta ttagcccaat tggaaggaac ttgcttggta acacgccaaa
    24841 gcgtacagac agccgcagcc gtacggaaag cgaagaagat gcttcgtaag gctttcgaga
    24901 acgctatggc cggtaagggt acttctgtgg tagagttcgt ctccacttgc tcatccggct
    24961 ggaagatgac tccggaaaaa gccaataaat ggatggaagc gaacatgttc cccttctacc
    25021 cgctgggcga cttaaagaat gttgaataag taatacggta aacgacaatg aaacaagaaa
    25081 taattatagc aggcttcggt ggacaaggtg tattgtctat gggtaagatc ttggcctatt
    25141 ccggtttgat ggaaggcaag gaggttagct ggatgccttc atacggacct gagcaacgtg
    25201 gcggtacggc caacgtaacc gttatcttga gcgacgagcg tatcagctca cccgtattga
    25261 atgaatatga tatcgctatt atcttgaacc aaccttccat ggataagttc gagaacaagg
    25321 tgaaaccggg cggtattttg atttacgatg gttatggcat ccatacgccc gcaaagcgta
    25381 cggatattaa cgtatatcgg gtagatgcca tggacgccgc taccgagatg aagaacgaga
    25441 aggcattcaa tatgttgatc ttaggcgggt tgcttaatat cgtcccgatg gttcaattgg
    25501 agaacgtcat gctaggattg aagaaatcct tgcccgagcg tcaccatcat ttgttgccga
    25561 tgaacgaggc tgccattaag aaaggaatgg agattataca gaaaatataa gaagctcatt
    25621 cattgatatg ccgatatgcc aattaagttt tctgattggc atattggcat attttataat
    25681 tggcacatta ttttttgtta tatctttgca acccatgaag tattatctat acatattact
    25741 ttttctgata ggaacggcgg cttccgcgca tgcgcaagga cgttccggga gccggggagg
    25801 acgaggtgga ttctcgttat ctaatttatc atcctcaaac aaggaaatac cggatagctt
    25861 gctgcaaaca gatagcgcgg cgctgaaatc aaaacgaatc atcggttatc ggctcacgcc
    25921 tcttttggga gaacgttata tcgctcctat ggataccaat cgattaaatt tcgggaatag
    25981 tacgttggtg gaagcgaact cattggccgt aggttatctg gcgaatgtgg gatcgccggc
    26041 gcaaacccgt atttttaacg aacgtaagga ggaacgtgat ttcatcttcg ccgatgccta
    26101 tgattattat atcacgaccc caacaaacgc ttatttctac gataccaaag taccctatac
    26161 ccaagtgact tatacgacag gaggagccag ccagaataag atggaccgac tgaaaggggt
    26221 attgaccatg aactttggca aaaagatcaa tgtcggtggc gagatggatt atatctatag
    26281 ccgcggatat tataactcca acggtaataa attattaagt tatcgttttt tcggaagtta
    26341 tatcaccgac cgttacgagt taaacgctta tttaagtaat ttcaatttcg taaactacga
    26401 gaacggtgga cttacaaatg accagtatat cacgaatccc gatgacttgg ccgagaatca
    26461 aagaaatatc gatagtaaat cataccctgt ccgttacacg gacacatgga accgtgtccg
    26521 tggaaaacaa tatttcctga cacagagata caatctcggt tttaccaaag aattggaaga
    26581 aaccgatgag gaagggaaca taaaagaggt attcattccg gtttccagta tcatccatac
    26641 catcgattac gaagataacc gcagacgctt tatctctaat gatgccggga tcgatacctg
    26701 ctacactcat ctttatggta tggacgcatc tttgaatgac cagacttcct catggaattt
    26761 aaagaatact tttgcgttgg ccttgcggga aggtttccaa gattgggcta agttcgggct
    26821 gaccgccttc gttactttcg agaaacgccg gtttagattg gcatcccaag ttcccggact
    26881 ggattacggt ccggatggtc gtggaagctc tgagccgagt acattaaatt tccctacttc
    26941 cgaggtatat gatgagttta cgacctacat cggaggcgaa ttatccaaac gccgtggtag
    27001 ccttcttacc tacaatgtcc gtggagaatt aggacttgcg ggaagtgacg ccggagaggt
    27061 tcgagtgagc ggagatctac aaacaaaatt caagcttttc aagaaagacg ctactatcaa
    27121 ggcggaagga tatatcaaga atatcacccc ggcgttttac caacgtcacc atcatgggcg
    27181 ttactattgg tgggatctat cattgaaaaa tgtgcaaagg atttacgccg gagcgaaaat
    27241 caacttggaa tccacccgta cccagttatc cggaggagtg gaaagtatcc agaattatgt
    27301 atttttcaac ggtaaaggtt tgccggagca aagcaataag aacatccaag ttgtctcagc
    27361 ccgtatcaag caagatatca tgtatcgtgc gttcggatgg gagaatgagg tggcctatca
    27421 gctttctagc gagaagtctc aacttccgtt gccggatatc agcgcatact cgaatatata
    27481 tctagcgttt aagttggcga aagtattaac cgtacagatt ggcgcgaaca tatactacaa
    27541 caccgcttat tacgctcctt attacgagcc ggctacccag cagttccaag tacaggaaga
    27601 agacaagaaa gtgaaggtcg gtaattatcc gttgatcaac gcttatgcga atttccattt
    27661 gaagcaagct cgcttcttca tcatggcata caatctaggc tctaagttcg ttgacccgaa
    27721 ttacttctct cttgcgcatt atccgttgga cccgatggtc ttgaaaatgg gtatctccgt
    27781 gactttcaat aattaatcga ttgccatgag atctaagaag ttgcttatcc tatacgcttt
    27841 tctactgatt gtcgctgtag tgacaatggt acagctttgg agacttaacc aacgtcccca
    27901 agagatcgga cctcgtgatt atccggaaat caaggaagaa ggaattcttc ggatgataac
    27961 cgagtacaat caatccggat atttcgtatc cggcgatacg gtgcaaggtt ttcaatacga
    28021 gcttagccaa gcgatcgcta aattatccgg attggaggtt cagacgcatt tggaaatgag
    28081 tttagcgaaa agtttcgagg aattatcgga caacaaatgc gacgtaatcg caagaaacat
    28141 acccatcacc tccgagatgc gggaaaacta cctgttcacc gaaccgatcg ttctcaacaa
    28201 gcaagtcttg gtacaacgta cggcagaggc gaacaacgga caagccccta tccgtaacca
    28261 attggattta gcccaaaaga ctttatacat accgaaagat tccccggcct tattgcgtct
    28321 gcaaaatctg ggacacgaga taggcgatac gatctacgtg gtggaagatg agttatattc
    28381 taccgagcag cttatgatca tggtagccaa aggcgatatc gattatgccg tatgcgacca
    28441 acaaatcgcc cgcatgaccc agaaaaacct gccggaagtc gatatcctaa cggatgtcag
    28501 ttttacccaa ttgcaatcgt gggcggtccg taaagactcc cctgtcctac tggatagcct
    28561 aaatagttgg ctccagcaaa tcaagaacag tggattatac gaccaaattt ataagcgcta
    28621 ttacaaatag cgctattcgt gagacggcaa aataaaggag aactctgaac ctacccctaa
    28681 ttcagaagta acatgtatcg aacctcccat cttaacaact aatcctttgc agatagccag
    28741 tcctaatccg ataccttcca tatagtcgtt tattttcacg aaacgaccga agacatcttt
    28801 caatttgtcc ttatcgatac cgattcccgt atcccttacg taaaaacgta attgattatc
    28861 cggttgaatg gtatatccca tcgtgatgct accttctttc gtgttcttga tagcgttgtt
    28921 caccaaatta ttaatcaact gcaacagacg catgctatcc gtaccgaaca tatggtggtc
    28981 agcccctttc tccaaaacta acttgactcc tcccggaacc cgtaacttgg cggaagcata
    29041 aatcgtatcc atcaattcac tgacatctaa ttgctcatat gtgatcttta tcgcatccgc
    29101 ctcgatcttc gagatatcca agatgtcatt gatcaattgc atcaacaatt ggttattcat
    29161 cttgatcaca tcgtagtacg acatacgttc ctcatccgta tcagcaaaag ccatcaattc
    29221 agagaagccg gtaatcgcat tcaaaggagt ccggatctca tggctcatat ccgccagata
    29281 tttcgatttc atcttatcag cggcctcggc cttcaccttc gcctcctcaa ggcttaattc
    29341 ttgattcttc cgttcctgaa tattcgttga acatccaagg ataaccgaag gtcttccttt
    29401 ctcgtcccgt tcatacacgg tagcaaatac ctctctccaa acatattcct tcttgccggg
    29461 aaatagcata cgtgcctcga tccttgcctc agagatttcc cctcggcaaa gacgggtaaa
    29521 catattatga taatgttctt gatcatccgg atgcgcccgg ctgataaact gcccccatga
    29581 cacctctatc atatcttccg acatggtatt ccaatcgttc aaggtcacaa cggaatcctt
    29641 gaaattatgg gtactgtccg gatcgatgaa aatcgagcat gtacgtatat cacttatccg
    29701 caatgccatt ttcgtcaaga tccgggttct tctcaaagta ttctccgtag ccaactcgga
    29761 agttatatct ctccataaag ccaagacaag cggcttgcca ttatttaggg aaataggata
    29821 tttagcgacc tctatatccc ggtaatcgcc ggaggccgat tttaccttgc ccttgaatct
    29881 agcggtcagt cctgtcttga tcacgttcat atcggtttcc agacgctcct cggcggtcat
    29941 caaggcatta taattcacct cgaaatcatc atgtccctcg atctcccggg tttcaatacc
    30001 cgttatttcc tccataaaat gattccaata caggtaatta aaatggttat ccccatcttt
    30061 cacgaaaacc cccaacggta accgatctaa tatcgtattg atcagttctt gtagattttt
    30121 ttctgttttc agagaagata catcgcgtgt ataaacgatt acaagctcct cattaaaaag
    30181 gcttgcttgc gatagataat aatagttctt tccttcaaaa gagacctcaa aagagaaatc
    30241 cactttcact tgctcctcga aaacacgttt aaccgcagct ctatagatct catattgatc
    30301 gtagttcttc ccgtccggga acaacgcttg aggttgcttt ccgatacagt tattcgctaa
    30361 ataatgataa taatcgtctt ttgcagaaat aaccttgaca agagtaagat ttcgatctac
    30421 taatacaatc gtatcgggac tcttctccat gatcatctct aatccagact gaacgttact
    30481 tccgctttct agactattca tattaattct ttcgtttttg gggtataact cggggataaa
    30541 ggtatttatt tttctattta tcaccaaaga gaaacctacc tattgcataa tatttctaaa
    30601 taatctttat ctttaccggg aatttgaatg taaaaagatg agatttgatg aattagattt
    30661 ggaagatgcc gtattagacg ggctttatga catgaatttt gacgaaacga ctccagtcca
    30721 agagttaacg attcctgtca ttttagaagg taaagacatc atcgcttgcg cacagaccgg
    30781 aaccggtaaa acggcggcgt atgttttgcc agttattaat gaactaagca aaggttgtca
    30841 tccgacagac gcggtgaatg cggtcattat ggcaccgacc cgggaattgg ctcaacaaat
    30901 agaccaacaa attcaaggat tcacttattt tataccttcc atatccgcag tagccgtgta
    30961 tggaggtacc gacggaatcg cttgggaaca acaaaagaga ggtttagaga tgggtgcgga
    31021 tatcgtgatc gctaccccgg gacgtttatt gtcccatatt aagttaggta ctgtagattt
    31081 gtctaaagtg tcgttcttcg tcttagacga ggcggaccgc atgctggata tgggttttta
    31141 tgatgacatc atgcaggttc ataaacagct gcccccctac tgccagacga tcatgttctc
    31201 ggctaccatg ccgcctaaga tccggacgtt ggctaaaacc atcctaaaag atccggaaga
    31261 agtcaagatc gctatctcac gcccacccga atctatcatg caaaccgcat atatctgcta
    31321 cgatccacaa aagctcaaga ttctacaaga tctcttcact caaagccgcc ctcaacgagt
    31381 aattatcttc tcctcttcta aaatgaaggt gaaagaatta gcgtctacct taaaaagatt
    31441 aaagttcaat gtagccgcca tgcactcgga tctagagcaa tcccaaaggg aggaggtcat
    31501 gaaagaattc aagagcggac atatcgatat ccttgtggct acggatgtcg tagcacgtgg
    31561 aattgatatc aatgacatca agttggtcgt gaacttcgat atcccgcatg atccggagga
    31621 ttacgtacac cgaatcggac gtacggcacg gggtacgaac ggcgaaggat tggcgattac
    31681 tttcgtatcg atcgacgaac aagcacaatt caaacgcata gaggatttct tggaaaaaga
    31741 ggtttataag ataccggtca gcccggaatt cggcgaagtg cccttgtatg agccggaaaa
    31801 atacggtatg aataaaagag gcagaggacg gcctcgtaaa agtgaagata aaggatcatc
    31861 ctcgagtcca caaaaacgaa atatgggaca tcgtggaaga cctaaaaagg cgcaataaaa
    31921 gcactatact ttttaataga aaaacactat acttttggag ctaaaacaat attgttttga
    31981 actcaaaagt atagtgtttt tttatgggat attatcaacc gttcatggat gccaagaatt
    32041 ccatattatc aacggtttgt tccatccgtt gcttaacaaa ttccatagcc tccatagagt
    32101 tcatgtctga tagatatttg cgtaagaccc acatacggtt caacgtgctc tcatcctgca
    32161 ataaatcatc acggcgagtg ctggaagccg tgatatccac agccggatag atacgtttat
    32221 tggataattt acgatccaat tgtaactcca tattacccgt acccttgaat tcctcgaaga
    32281 tcacgtcgtc catcttagag ccagtctccg taagggcggt ggctagaatc gtaaggctac
    32341 cgccattctc aatattacgg gcggcaccga agaaacgctt cggcttctgc aacgcatttg
    32401 cgtccacacc accggaaagc accttaccgg aagccggttg taccgtatta taagcacgag
    32461 ccaaacgagt gatcgagtcc agaagaatca cgacatcatg accacattct accattcgtt
    32521 tcgccttgtt caatacgatc tcagcgattt tcacgtgacg ttcagccggt tcgtcgaatg
    32581 tagaagcgat cacttccgca tccacgctac gagccatatc cgtaacctcc tccggacgtt
    32641 cgtcgatcaa taatataatc atataaacct cgggatggtt gtaagcgata gcgttcgcaa
    32701 tatctttcaa caacatcgtc ttaccggttt tcggttgagc gacgatcaaa ccacgttgcc
    32761 cttttccgat cggggagaat aaatcaacca cacgtacggc gatattatcg tatactttcg
    32821 gtgatttacg tgccgtaagc atgaatttct catccgggaa taacggggtc aaatgatcga
    32881 aaggaacccg gtcgcgaacc tcttccggcg tacggccatt gatcttgtcc actttcacca
    32941 acgggaaata cttctcacct tccttcggcg gacgaatcga gccttctacc acgtcacccg
    33001 ttttcaagcc aaataacttg atctgggatt gagagacata aatatcgtcc ggtgaagtca
    33061 aatagttata atctgaagaa cgaaggaaac cgtaaccatc ttgcatcatc tccaacacgc
    33121 cggttcctgt aaggatgccg tcaaactcat acattttctc ttgagcctgc tggttgttat
    33181 tagcgttatt gttattacgg ttgttattat gattattctg tcgattgttc tgtcgaggat
    33241 tattctgctg gggagcggcc tcgggttgag gtttgttagc ctcgggtttc ggagcggaga
    33301 acgggaaaat ctgatccaat acggatttag cgtccggatg gcgaaatacg atgcgcttag
    33361 gctcttcttc cgtcgcttgt ggtgaagtgg tttcttccgc tacctctacc ggagtcgtat
    33421 tttccggcaa agcggcttct tcttccgttt caagttccgc cacaacagga ggcaacaacg
    33481 gtttctccac cgggctctct actaccgccg gagtttccac ggccgagatt tccgttacca
    33541 tagagatcgt ttgcggctct ttcgaaacca ccacttcctt gttatcctcg gaaggagcga
    33601 tagcgcccgc taccttttcc tttttctcga tacggactct tttcttacgt tcaggctgct
    33661 ctttttgctc tttcttgtca gccggagcag ccactggctt ttccgaagcc tgttgggcac
    33721 tctctgcagc ttcggcagtc tcagccttcg ccactttagg agaagcggct ttagccggac
    33781 ggcctctctt acggccctct acaggcttct tagcctcttt ctctttcatc ttttcagcct
    33841 gaatgccggc ataggagatc gcttgctcat caagaatccg ataaaccaac tcttctttct
    33901 ttaagctgct aacttttttt attcccaact cttccgcgat actttgaagt tcgggaagaa
    33961 gtttttcatt tagttctaga atgttatatt tctgcatatt gcgaagtaat aatataaatg
    34021 gcacatacac acggatcaca tatgcaaaca cgacgtacgc ccaatggtat cattgtatct
    34081 ttattaaatt ataattttca tgtaataacc ggattgttca gctaatttga accattagta
    34141 acatatctgc ggagtaaatc ttcgcaaatg taagaatatt tttacaataa acgaggattt
    34201 agccaaaaaa attcacaatt agcacacgct ttgttgattc gtctatacga aaacgattat
    34261 cagtcctttc tcctaccacc caaacgatag cgtcgccact acaaagaagc catgtgcgct
    34321 ccttctcaat ccggctaaat ttatgatcgg agaaatagtc actcaacttc ttacgtcctt
    34381 tcattccgaa gggaataaac caatcgcctt ctttccaagt ccgcaatgtt aaagggaaat
    34441 cgagtttatc ataatccaaa taagcgatcc gcttattctt ctcgataggg aaatctatag
    34501 ttataacaag tttttggaaa gatagttcaa taggttcatg attaatgccc ttttctggat
    34561 ctaaaacgaa ggttcgcttt tccttcttct ctaaagaagt gatccataaa taatcccgat
    34621 ccttcagcaa acgatgggtg gaagagtaaa acagcttacc aggctccttg gtcaaggcag
    34681 cgaaaatatc gtccgagacc agacgggtaa aaccatattc ttttaataac tcatacaaaa
    34741 tcgtctccgg agccggaaac cgcatcaacg ccccgataga aagacgatca tccgatacga
    34801 caacctcttt ccgggcttgt tccaatacat atatatatat agtctctgcg gcagaaagat
    34861 gctcggcgga acgtgcgatg gtattccggg ccgatggatt tatctcctcc aaaagcggca
    34921 acacattcaa acggatgaaa ttacgggtat aagcatccga taaattcgtg ctatccacca
    34981 tataggcgta gccttgatcc gccagccaag ccaagatatc ctcacggctt acgcacagca
    35041 aaggacggac gatgaaacca ttcctcggac ggatcccgct catcccccgg attcccgtgc
    35101 cccgtatcaa attcatcaag accgtctcca cattatcgtc ccggtgatgg gcgacggcgg
    35161 tcgcctgccc tcccagccgc tcccgcatct cctcaaacca agcatagcgc aattcacggg
    35221 cagccatctc tatcgagaga tgcctctctc cggcataaga gatcgtatcg aaatctatct
    35281 tatgaaaggg tacttccaaa gattccgcga actcacaggc aaatgcctca tcccgatccg
    35341 actcctcccc acgcaaatga aagttacaat gaagcgctat acacggatat cccaaacgca
    35401 ccaatacgcc caacaaagcc acagaatcgg caccaccgct caatccgacc aaaaccggac
    35461 gatcctcgga taacagccgg tacttctcta tatataaacg tatcgtatgt atcataacat
    35521 ctttgtatta aaaacaataa tggccctagc cggttttagc tagagccatt acttatagat
    35581 cttttgaatt aatcttctac acctgctaat tccgggtcga tcataatacg accacagtat
    35641 tcgcaaacaa taattttctt acgcaacttg atatccaatt gcttctgagg cgggatcttg
    35701 ttaaagcaac caccgcaagc gccacgttgc acataaacaa cagccaaacc gttacgagca
    35761 cctttacgga tacgcttgaa agcggtcaac aaacgaggtt cgatagtggc ttccagcttc
    35821 ttcgctttct cacgaagttt ctcctcatcc tgctttgtct cggaaatgat ctgctccaac
    35881 tcgctctttt tctgaaccaa gtcagcctta cggccttcca gcttctcagt cagttcagcg
    35941 atatcttttt tcttagcgtc taccgcctct ccgaactcac ggattttctt ctctgagaac
    36001 tcaatttcca aaccttggaa ctcgatctcc ttggacaggt tatcaaactc ccggttatta
    36061 cgcacattat ctaattgtgc cttatagcga tctatcaatg tggtagattc cgtgatctta
    36121 tgcttttgct caacaacaga agcctcaaac tccttgatct ccgcctgata gttctggaga
    36181 cgtgtttcca gtcctgcgat ctcgtcctcc aagtcttgaa cctccagagg aagctcacca
    36241 cgaagggtct tgatcttatc aatttcagtc atcatcgtct gaagttgata cagcgtagaa
    36301 agcttttctt caaccgtata ttccttttca gctgattgtt tatctgtagc cattctataa
    36361 atattttact gggtttgaat taacattcga aaaatgtacc gcaaaggtag ggaatttttt
    36421 cgatattatg ttataaaata tgtcttttgt acagatttcc gattcataat gaccgataac
    36481 cgccagtaga atccggtcct ccacatcgta aaaatcgttg tacttcgcct cccccgttat
    36541 aaagacatcg gcaccatacg cgatagcgtc cttgatcaag aaagcgccgc tgcctccgca
    36601 gatagcgacc tctcggatag gcttaccagt aaatggggaa tgcttcacgc aaccgacgtt
    36661 aaacagggcc ttgatccgca acaagaaact caactcatct tcctcggcag gcaactctcc
    36721 cactacaccg gaacctgcct gttcccatgt gtttgataac gaataaaaat caaaagccgg
    36781 ctcctcatac ggatgaacgg ataacagggc acgggtcacc gccgtcttct tgaatgccgg
    36841 aaggatcatc tcgatacgca cctctttctc tacatgcaac tcgccgatct caccacaaaa
    36901 cggattgcat cccgcattgg cacggaatgt tccctcgcca tgtaaattat aactgcaagc
    36961 atcatagttc ccgatacttc ccgcaccggc attgaacaag gtattccgca tgatctcggc
    37021 ataagcctcg gggacaaacg tcaccaactt cagcaaagcg cctttttggg ggctcaagat
    37081 ccgtacattt tgcaagccga tcaactctgc caaacggtaa ttcacgcctc ctacggcatt
    37141 atcaagattg gtatgggcgg cataaaccac caaatcatac ttacacgcct tcatcatgca
    37201 acgctcgata taattggagc cagtcaacga cttaaacgac ttaaaggcca aaggatgatg
    37261 agagatgatc aggttgtatc ccatctcgat cgcttcatca agcacctcct cggtaacatc
    37321 taggcatagc aacacacccg tcgcatgctg gttcacgtcg ccaacttgca cacccgcatt
    37381 gtcaaaacct tcttgaagcg gcagcggggc gtaatgctcg atttctctca atatatcttt
    37441 aacctttacc atgctaaata tcttttgatt tatgttcggg agaaaaagta attcctttcg
    37501 gaagaaaaga aaattccatt cagatggaat aagattccca ttcgaatgga atttcagatt
    37561 ggattatttc ttgatatcaa cgatcaaatt cagttcgtcc aactgggccg gatccaagac
    37621 acccggagca tcgagcataa catctcgtcc agaattgttc ttcgggaaag cgatacagtc
    37681 gcggatagaa tccaaaccgg cgaacaaaga cacgaaacga tccaagccat aagccaaacc
    37741 tccatgagga ggcgctccgt acttgaacgc attcatcaag aaaccgaatt gctcttgcgc
    37801 tctttcttcg gtgaatccta acagcttgaa catcttatcc tgtaattggc tgtcgtggat
    37861 acggatagaa ccaccaccca cttcaacgcc attgataacc atatcatacg cattcgcacg
    37921 aacagcgccc ggatccgtgt ccaacaacgg tatatcatcc ggattcggag aggtaaacgg
    37981 atggtgcata gcgtagaaac gttgatcgtc ctcgttccat tcgaacagcg ggaagtcgat
    38041 tacccacaag caaacgaact tatccttgtc acgaaggcct aattgattac ccatctctaa
    38101 acgcaactcg caaagttgct tacgagtctt catcgcatcg tcgccggaaa ggatcaaaat
    38161 caaatcaccc ggcttagcgc cgaacgcatt cttcatttct tgaagaacct cttggctata
    38221 gaatttatct acgcttgatt tcacgttacc atccgcttcc acacgggcgt aaaccaaacc
    38281 tttagcacct acctgcggac gtttcacgaa ttcagtcagc gcatccagtt gtttacgggt
    38341 atagcttgca gcaccttccg cacagatacc ccctatgtaa gcagcgttat cgaatacgga
    38401 gaaaccatgg cctttcatga tgtccatcaa ctcgacgaac ttcatgccga aacgcaaatc
    38461 cggtttatcg ctaccatatt gtttcatagc atcttgccaa gtcatacgca taaacgactc
    38521 cttgaactcg acaccacgga ttaccttaaa caaatgtttc gccatgccct cgaacatatt
    38581 caagacatcc tcttgctcca cgaagctcat ctcacagtcg atctgcgtga actccggctg
    38641 gcgatccgca cgcaaatcct cgtcacggaa acattttacg atctggaaat aacggtcgaa
    38701 accggaaacc atcaacaatt gcttcaaggt ctgtggagac tgaggcaaag cgtagaactg
    38761 tcccgggttc atacgggaag gaaccacgaa gtcacgggca ccctccgggg tagaatttac
    38821 aagaaccgga gtctctacct ccaagaaacc ttgctcatcc aaatagcggc gaacctcgaa
    38881 cgccattcta tgacgaagtt ccagattctt acgaacgcaa gcacgacgca agtccagata
    38941 acgatatttc atacgcaagt catcaccgcc atctgtctcc tcctcgatcg tgaacggagg
    39001 ggtaagcgca gtgttcagga catttaattc agaaacgatc aactcaatat cacctgtcgg
    39061 gatatgcgca ttcttgctgg aacgctcacg aaccgtaccc gtaacctgaa tcacgaattc
    39121 acggcccagt ttattcgcct tttcgcaaag agctgcatca acctcctgat taaataccaa
    39181 ctgagtaata ccataacggt cgcggatatc gacaaatgtc attcctccca ttttgcgggt
    39241 tttctgcacc caaccggcca gtgtaaccac cagaccttca tccgcaaggc gcaagtcgcc
    39301 acaagttctt gttctataca tctttattat ttaatttgct agatttacca atctttatac
    39361 ctcggtttat tacaaaccgc aaccacaaag ataatactat aaatcttaat aattattctt
    39421 ttaagcaaat taaaatacgt tttaccctct gctacccaag ctgtccgtat cgggattaat
    39481 ctctttcaca gcctccttta catccttggc cgttattttc ttctcatttt taacagcgat
    39541 ttgctctaca ggatactttt cctccatctc ctccaattta gagtctacgg atgtttttga
    39601 atcatttgtt ctcatattct ctattttatt aacgtaataa tggctattaa acaagcaagt
    39661 actgccaatg gtttatagcg atagcgacat tgtccgtgaa catggaagga gttatgggaa
    39721 tgcgagacat tatagcacat cattatttcg atatagacgc tgttatagtg tttgatgtga
    39781 tgaaaaataa tctgccagcc ataaaaatga ctattgataa aatgttattt gatatttgag
    39841 acaccttccg tgagcgatac tgtggatgag gacaaaaagc tatttacccc cggatgagcc
    39901 tcttatagag caacgaacgc aagccattag ggagaagacg ggtcactaag cgaatacaga
    39961 cattctttag caaggagaaa aagccgataa aacccatctt gtaaaacagc gtctgcaacc
    40021 tcacttccgt tacggcatac cgccatcctc cccgccgccg aaacatatcc ggcgagaagc
    40081 ggaaaaagag caggctctct tgtatattat agaaccgggc accattcatc agcatccgta
    40141 cccacagata ataatcctcg aacaaaggaa aatgcttata tcctccagcc tttagcacgg
    40201 ccgacttccg aaacatcacc accggatggt tcaccggaca ccttcccttg gcaaacctca
    40261 agatattttc atgctgctcc ggcactttcc gcatggaaag tacatttgat acctcccctt
    40321 caaactcatc gatccaagcc cccactacat caatttccgg atgttccaaa aatatcgcca
    40381 attgcttctc aaaacgatcc ggcttagcga tatcatccgt gtccatacga gccacaaggt
    40441 catacgaaca atgcttcagc ccctcgttaa gagccttgcc gagacctcgg ttggtgggca
    40501 aagaaatcac ttttaactca ggatgctggc ttgtgaattc ttttatgacc gcatacagct
    40561 catccgtcaa aggaccatct tccaccaaga caacttctat aggcaatagc gtttgcgtga
    40621 agatactggt cagactttga cgtaaaaata gtgggctctc tttatgatat aaagaaagta
    40681 atacggaaaa taacatagac tttcaggaaa agtattatat aagaaaaatt tctatatgta
    40741 catataagat gtatccggaa cacttgaaga ttgactcttt acagagtctg tacgtaaaga
    40801 accgtctcaa atctatcttt ctcattctca tgatcctaat ctgcctcata aaaaaaacaa
    40861 ctctctgatt tacagaatta aaaaacataa acattcttca taaccacatt acaccagctc
    40921 atctcttcgt tgcaaatttc atacccactc tacttaagac attttttagc gctctccgtt
    40981 gcttaggtga tattttccac tgaagccaat tagtcatatc aatctttatc tgttgagaga
    41041 gaggaacaat gcctctacca gaatctatat acaagctcaa tctactcaaa ttttcaacag
    41101 catgcctaat ccatttacct ttatatactc catgtatata tggcaagata tattctgaaa
    41161 ctgccaccac atctttataa tcctctgatg gagcaacagc ggcttgttca tttattgagt
    41221 tttcaatatc ccatgcacta agagagccat cgcctaacag ctcaacaaaa agatcctttc
    41281 gaaatattcc aaattgaaga ttgatagcat aggggatttg cttattgaca ctacgcaata
    41341 aaggaaaaga tttaatttta gatcctttag gagtagggcc taaattacaa taccttatct
    41401 cgtggctatc catatagtca agtaaccgct ctattaatga attgtcaaca ttgtcactca
    41461 agataatgtc atcacacatc aacattacat acttcgattt tataactggc aaagccgcta
    41521 tagtacgctc aacccaagta tcattttgct tattattgca tatacaagta ataccttcat
    41581 acgatttggt attggtggtt agaataaact catagggaca atcactccaa tatctccgat
    41641 acccttttaa aaatacggca agcacatcag aatacgaatc aggagaacta acataaatag
    41701 aaagtcgctt atccatcagc tattgtactt tttctatata ttccttcaaa ctcatcaagt
    41761 ttttatcctt gtcagaaatg atcaatttct caataccgcc aatcttatcg aaaggccact
    41821 ctatagccat atccggatca ttatacatta tgccggcatc accttcacca taaaacacct
    41881 caccacattt atagctaacg acagaatcct ccagcaccaa atagccgtgg ccaaaatact
    41941 gaggtatgta tagagccttc tgattctctc cggtcagatc aaaaccttgc catttaccaa
    42001 atgttggcga atcagggcga agatctatga ttacgtcata cacatggcca cttatacaac
    42061 gaacaagctt ggcttgctgt ttaacaagct ggaagtgcat cgcacgaatt acaccctttt
    42121 tactaatggt atagaacacc tctttaagtt catgatctat accattttgc ttaaatgcat
    42181 caatattgta atcctttata aagccaccac gttcgtctgt ggcatagaag ggagttatct
    42241 catatgcccc cttcatatca agtcccttga attcaaattt ctgtatcatg actaattccg
    42301 ctataacatc aaagagtttt taagccaatt aatagtttta tcaatgcctt tatcaaagtc
    42361 tatagacgca tattctccaa tagtactaac caagttacta ttgtcaaaca tatccattgt
    42421 atactttaca ccatcatctt cacggactcc tatccctacc ttatctgcgc aaccaactag
    42481 ttctcctata cgaataagat aatctttcaa gactctagga ttgccagagc ctatataata
    42541 gaacggctta ttcgtttcct taaagcctag acgatataca gcttctataa gatcatccac
    42601 ataaataaaa tcatatggtt gtaaagctgg accaaatgcg gcttctttac cagccatcaa
    42661 ctcacctaac gtataactaa ccaaattgcc cgttttatta cctacaccgt atatatttga
    42721 gaactgcatc cacacaaact gttgagcgat attcttgcaa taatcttcca aaattattct
    42781 gcaagcatgc ttagccacac catacatcat tccaccagtc gtttttttca gatgcgacaa
    42841 actaaatgca acgttctccg ctacagtacc cgcacaaaga aattttttca catttaacct
    42901 cttgcaaata ttagcgcaat ctactgccat ctgaatattt gataattgaa ccgtaggatc
    42961 tgctttatca gccccattta cacctttcca cgcaaaatga tagaaagagt catattcaat
    43021 tactggcagt ctttcgacta gagatgtatt cacccctgat tctatcctcg taataagatt
    43081 tgaatcaggc aaacgattgc catgaaaggt aatatcaaca gcaacaaccc tagtaccttt
    43141 ttctatcaat ttctttataa gtgaactacc tataaaacca ttgccccctg tgacgattac
    43201 gttcttcata ttatcgttat acgtttaaaa attcatctat ctgtttatcc atacaaacac
    43261 gaacatcccc acctgctagc caaaccttac tccattcaac aatcttttcc attgcctcat
    43321 ccagattcca tcgagggctc catccaaaag tctttttcaa cttagagcaa tcaagcttca
    43381 agaaatttgc ctcgtgagga ccaccatcat acttgttcac ccacctcatg ccttcgcccc
    43441 acttgttcac aaataggtca acaagagcgc ctgtttgaaa acaatccaca tcatcgggac
    43501 ctacattata ataatccgca aaaccgatat cctcatattg cttcatcgct atcagcaggt
    43561 aagcatacaa aggttctaga acatgttgat aaggacgggt agagtatgga ttacgcacaa
    43621 caatatcctc atgttttaca gccgcacgga tacaatcagg tattattcta tcactggcga
    43681 aatctccacc acctatcaca ttacccgctc tagcagtaga aataggaata ataggcagac
    43741 catcaatatc tgtaaagaaa gaacgcttgt agctatgagt caccagctcc gaacaggatt
    43801 tggaatttga ataaggatca tacccatcca attcctcatt ctccctataa ccccaactcc
    43861 actccctatt caaatacact ttatccgtag tgacattcaa gaaagacttc acgcaacaat
    43921 tattgcgaac acactcaaga atattcacgg tacccatcac gtttgtctcg taggtatagg
    43981 caggatcttt ataagaatct ctaacaatgg gctgagcggc aagatgcagc acaatttctg
    44041 gttgagactc atcaaaagcc ttctttagag aggcataatc tcgtatatcg ccaatcacgg
    44101 aatgtatgtc atcttcaata ttagcaattt gaaacaacga aggctctgtt ggggcttcaa
    44161 gtgaatatcc ggtaacgacc gctccggcat tagcgagtat cctacacatc caagagccct
    44221 taaagccggt atggcccgta aggaaaatcc tcttgccttt ataaaaatcc aatatatttc
    44281 ccattcgtat gataacttat tattttgcgt aatctggtat ttccggaaca gagcgctccc
    44341 aacgcttcca aggagcttta tcctcggcaa gcagtttttc aagcatagat ttttcacgta
    44401 tattatccat gcactgccaa aaaccagtat ggatataaga catcaactga ccctcttgcg
    44461 ctaacctgac aagtgcggtc ttttcgaaga cacaagagtc acccccttcc agcatatcaa
    44521 aaacctcggg ttctaacacc atgtaaccgg cattaatagg agcgccatca gaggcgttct
    44581 tttcccgaaa agcccttacg gcttgatctt tagtaatatc taagactcct ttatcttgtg
    44641 ctatcttgac ggccgtaagg gtcgcaagct tgccatggct cttatgaaac tccaccaatt
    44701 tatcaatttc tacatcacaa acaccatcgc cgtatgtcat caagaaagtc tcattctcta
    44761 tatatctctg gatacgctta atacgacctc cagtcatagt gttgtagccc gtatcaacga
    44821 ctgtgacttt ccaaggctcc ataatagttt gatgaacggt catttcgttg ttgccaccac
    44881 gatagtcgaa agtcacatca gagttatgaa ggaaatagtt ggcgaaccac tccttaatat
    44941 attcctgttt ataaccggcg caaatgataa actcggtata accataatag gcatactctt
    45001 tcataatgtg ccacaagatt ggcataccac caatctcaat cattggcttc ggcttgaact
    45061 gagattcctc agatatacga gaaccgaaac ctcctgcaag aagtactact ttcatgataa
    45121 agaaaagatt ttttagttaa gtaatcagct aaagctaaga taattaagaa ttaaacttgt
    45181 ctttataaat tgtataatca ttatgtatat caacaaaaac tgcatgaata ggatattctg
    45241 taaaaatatc agaattaggg attttcataa aatcgctacc atacctaaga gaaagatatt
    45301 tttccgcttc aaaaggaata ggtaaaagga gattctcaaa attcacatag cgctgaattc
    45361 ctaaccattt acgaggaaaa ctcgttttgg gaaacggagc ctttccaaaa aaatggccaa
    45421 caagtaacgt atttttagtt gaaaagtgat tcaatatttt gaataaaaag ttttttgctg
    45481 tagtacctac aacaaaatga caagaattaa taaatacttt cttgaaaaag ctatcagaat
    45541 cgtaatctac caaataaaga gatgtagctt ttaaaatttg agcggataaa tattgaatat
    45601 aacgaacaaa cttattaggt gatacattat acaaacacat tatatcaata caaatacctt
    45661 gatgcatttt attatatcct ttttcaatac aagttgttcc attcattctt aacttagaaa
    45721 aaaacaaagg ccactcagta gaattttctc tttgaagatg aaatttttct gtatcaagat
    45781 gtatagaagc ataatgaagg aacttatgat aattattaaa agtcataaaa acgtcaaaat
    45841 catcatccca tggaataaag ccatgatgcc taacagcacc taaagcactt ccacccatta
    45901 aataatattc tatatcatat ttcttacaaa actcatcaaa ataaaacgct atttctaata
    45961 ttttatattg aaaatcttta atatcaacat tcatagtagt aatttaaact agtttatcac
    46021 gcaatatagt agaagaaata cctttagtat aaggaaaata aacaacttta gctccattct
    46081 tattcaactc agcttctact tcctgaaaca aagaattacc tttccagtca tcaccaacaa
    46141 acatcacatc gaaatgcaaa cgatgataag cagacatttt atctcgatta acttgaggaa
    46201 ctactttatc tacatatttg caagcctcaa caattgcctt acgattatca taagagatta
    46261 taggactttt atgcttatac tctcttacca attcatcggt actaacacca acaattaaaa
    46321 aatcacacaa ttccttagct cgttttagta tgtttaaatg accaatatga aacatatcaa
    46381 acactccaga agtgtatcca ataataaaat tttcgtgaca cataattata tattatttca
    46441 acaaactatt atacaaatcc acccacctta gcataacatt ttttacagta aaataatgga
    46501 gacaattaaa agcattctct gaaagtttac aacgcaattt ttcattagta attaagtcat
    46561 aaatcgagcg agaatattca gatatgtcca aagacttaat aacttttgaa ttaacatcat
    46621 taattaagaa acctcgaata gccatacaat catcaaaagc aatagggact actttcatct
    46681 gcatagcttc aagcagactt agtggagcac cttctaataa agaggtaaac attagtattg
    46741 acgaacgttc aaaatatttc tttgaatcat cacgcccaac caatttcaca tttacaatat
    46801 catttttatt tataaagtct ttataaacag attcccactc tccataacca actatagtta
    46861 aacaccaatc tctcacgtca taagtagata aaaaatgttt ccaaattttt aatgctagta
    46921 atatacgctt agatatttca tcaaatcgag ccacaattag caattcattt gttttagaat
    46981 agttacgctc aacataatca aatgagagaa aattgggaat tgagaccatc ttagaagaat
    47041 ccttcaaatt agcaatagat ctataaatgg gtatataagc atcagatagg agaactaaag
    47101 catctgagta tttatagata gatttatact tccttttggt aatatattta actagaaaac
    47161 gagtaatagg gtagaagaat aacaataaaa gataaataag ccacttaaaa gaaatccgcc
    47221 tattaagaac ttgaaacaaa agagattgct tattatatct aatattctct gttcctggaa
    47281 gattatgcaa aactgatata attttcactt ttaatcccgc aacagcttga ccaaggaatt
    47341 tcatattaac agctcttgat gcctgattat gaataataga aatctcatta tcaataagaa
    47401 aagaacggaa accatctaaa tcattataat caattttaaa tttcgcatca aagactaatt
    47461 gagaggaact atattcagaa tctttaaaat aagctataaa acaatgaatt ccaacactag
    47521 acaaatattt ggcagacaac aaagtgactt tttgattgcc actacctgat tcagaaggat
    47581 ctaataaact aataaacaag atattcatga tctatactta tcaaataatt tacgatatat
    47641 tttctgaaaa ggaatatagt gattcttata accatctata acacatatgc ttttataaaa
    47701 atttatcgtg tgcaaaccat ccgagtaata tgacgaggaa tcaggataaa gggatattac
    47761 ttttgtttca ttataggact tatctgaaat atcctcaact ttatacagaa taataccttt
    47821 accataccct tgcaaacaat cctgagctgg tctgtataca gtattattta cgtacatgaa
    47881 atcaccagcc attctgctcc caaacaaatt agattttatt aatattggag acaaatcgta
    47941 tccatataat ctattatttg aagtccacat atacaaatcc ttattatatg catttcttga
    48001 agttgcaaaa agataaaagg ctccattata aggcaagatt gtagcatccg caactgcaac
    48061 aggaagcata gtactgaaat gttcacaaga atgtaacaaa gtattatact tataaacatt
    48121 aagttctgta gaatacgaat tttcaggaac aatataaacc tcatcaagag tatcacctct
//
LOCUS       DBMDTB010000017        47395 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_305_length_47395_cov_9.599188, whole genome shotgun sequence.
ACCESSION   DBMDTB010000017 DBMDTB010000000
VERSION     DBMDTB010000017.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 47395)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 47395)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47395
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_305_length_47395_cov_9.599188"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..480
                     /locus_tag="ACZPB4_04685"
     CDS             <1..480
                     /locus_tag="ACZPB4_04685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007843366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase beta subunit C-terminal
                     domain-containing protein"
                     /protein_id="HIR1097552.1"
                     /translation="VQFPAGGSITIIAVTTLSGGDITHAVPDNTGYITEGQLYLRRDS
                     DVGKVIVDPFRSLSRLKQLVTGKKTREDHPQVMNAAVRLYADAANAKTKLENGFDLTD
                     YDNRTLSFAKDYSSKLLAIDVNLDTTEMLDVAWGLFARYFSPEEVNIKQGLVDKYWK"
     gene            492..1115
                     /locus_tag="ACZPB4_04690"
     CDS             492..1115
                     /locus_tag="ACZPB4_04690"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005638772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HIR1097553.1"
                     /translation="MAIKFQYNKTSLQQLEKQLKMRERSLPTIKSKESALRIEVKRTK
                     DEVNKLELQLEREIQSYENMVALWNEFNPELISVKDVTLSTKKIAGVIVPLLDEIKFE
                     IGHYSLFNAPAWYTDGIELLKKLARTGIEAEFSGMKLELLEHARKKTTQKVNLFEKVQ
                     IPGYKDAIRKVKRFMEDEESLSKSSQKIMRANQEKRKAKEEKEEAEV"
     gene            1112..2932
                     /locus_tag="ACZPB4_04695"
     CDS             1112..2932
                     /locus_tag="ACZPB4_04695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0033179 - proton-transporting V-type
                     ATPase, V0 domain [Evidence IEA];
                     GO_function: GO:0046961 - proton-transporting ATPase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HIR1097554.1"
                     /translation="MIVKMSKYAFMVYHKEYDTFLSTLRDLGVVHIKETNSVMDNERL
                     QELLAERKQINTLMRYFKNLHAAEKDVKFAPARELTKEEGLKLVRKIEELQDKKAQLI
                     ASKQSIEKDLAYMEIWGEFSYQNINRLKRAGYDVTFFTCPTAKYEPEWGVLYNAILIN
                     NFQSVTYFITITKEGTLIDIDAERPKMPVQGLAKLRARLDQRTKDIQNVEDELKHRAV
                     GDYKTLEEFDKNLQDEFNLSNALVQTDRQAGDKLMLLEGWVPTENAPALEHELDKQGY
                     FFQQLEIEDGDKVPIKLRNNKFSKLYEPITKMFSLPNYGELDPTPLFAPFFMLFFGLC
                     FGDGGYGLLVMIACTILKKKVNPDFKPYLTLFQYLGFAALLVGTCTGSFFGVALADIP
                     ALSKIKNYFVNSDNLMTFSIVIGLVQIIFGKCVAAYKIKIQKGTKHSIAPFAWVFVII
                     SLALAFGLPMLNVHLPNAVVMVCYGIAILGLVVAYLYNTPGKNVFLNFGTGLWNTYNM
                     ASGLLGDTLSYIRLFAIGLTGSILGGVFNTLAVTMTDGMNIVARAICMLLILLVGHSI
                     NIALCTISSLVHPLRLIFVEYYKNAEFEGGGKAYEPFRKA"
     gene            2987..3442
                     /locus_tag="ACZPB4_04700"
     CDS             2987..3442
                     /locus_tag="ACZPB4_04700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HIR1097555.1"
                     /translation="MEPILLAYVGIALMTGLTFIGSSYGVTIAGNAVVGAMKKNPDAL
                     GTYIALSALPSSQGLYGFVGYFMMQKFLVADISMLAATAVFGAGLVLGFAGFYSSIRQ
                     AQVCANGIAGVGAGHNVFGATMVMAVFPELYAILALLVVILIGGTIPVA"
     gene            3603..3968
                     /locus_tag="ACZPB4_04705"
     CDS             3603..3968
                     /locus_tag="ACZPB4_04705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HIR1097556.1"
                     /translation="MKRLTVKEEEIMGWFWQKGPLFVKELLEYYEEPKPHFNTLSTIV
                     RGLEEKGFLAHKNFGNSYQYYAVLTEKEYSNGTLKNVIAKYFNNSYLGVVSTLIKEED
                     ISVDDLRKLIDDVEQGNRK"
     gene            3977..5446
                     /locus_tag="ACZPB4_04710"
     CDS             3977..5446
                     /locus_tag="ACZPB4_04710"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HIR1097557.1"
                     /translation="MGIFFVYILKSSVCLTIFYLFYKLLLSRDTFHRFNRIALLSLIM
                     LSVIIPFCEITLEKATAIQRPVMDLENLLAAVSMRTSAESASQPVWLRVMVIAYIIGG
                     ILTLCQFAYSFYALFRLMRQGTPKLVDGIHLILTDQPVAPFSWMQTIVISRKDFEESG
                     IEIMTHEMAHIKARHSIDLLISEICILFHWFNPSVWLLRQELQNIHEYEADESVLNQG
                     VDAKRYQLLLIKKAVGAQRFTSMANSFNHSSLKKRIAMMLKQKSSPWARLKYLYVLPL
                     AALTVVAFARPEISHELEKISSVKISEIIPVQEKKEPKRNVEVETLARDSVVSEKDMQ
                     AIQEKVSAVMEKYQPEIDKAVEEAVKAANIDEIVSAEMAKHQAEIDKAVQAAIEAAKI
                     NETIAAEMEKIQPEINRAIEEAMKAIDINEKAAKEASKEKSSFSGIVYIDGMESSKER
                     MDNLNPDRIASMNVYKGNEAIAKFGEKGRNGVIEIKLKK"
     gene            5443..5934
                     /locus_tag="ACZPB4_04715"
     CDS             5443..5934
                     /locus_tag="ACZPB4_04715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4934 domain-containing protein"
                     /protein_id="HIR1097558.1"
                     /translation="MIFAYICKVGLFGSLCAGMFLTSCMERENEEASKRVIEVGKAIS
                     SPAELKASDYFDEIRYVPLETRDDCLVGSSPDIKLLDKYILITSANRQCLLFDKATGK
                     FKCQIGHVGKDPGGYRNVDCLVDELNGRLLFNGWGHDLISYNLDGNYIGKIELLIFLR
                     KYS"
     gene            complement(6022..6408)
                     /gene="crcB"
                     /locus_tag="ACZPB4_04720"
     CDS             complement(6022..6408)
                     /gene="crcB"
                     /locus_tag="ACZPB4_04720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:1903425 - fluoride transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:1903424 - fluoride transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HIR1097559.1"
                     /translation="MIKVFLLIIGGAIGSALRFGVSTWVQRSMLYSFPFGILSVNVIG
                     SFLIGFCWSIAEAYNFSINTRAFLFTGLFGGFTTFSSFALDTMVLMRTGEYKMALLNV
                     LASNILGLIAVFLGIILGKNIITMIK"
     gene            complement(6479..7498)
                     /gene="pheS"
                     /locus_tag="ACZPB4_04725"
     CDS             complement(6479..7498)
                     /gene="pheS"
                     /locus_tag="ACZPB4_04725"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HIR1097560.1"
                     /translation="MLDKIKALLQEVENMKAANAEELEALRIKYLSKKGEISALMNDF
                     RNVAADQKREVGKYLNELKETTQSKINELKESFENVQTANDDIDLTRTAYPIELGTRH
                     PLSLVKKEICDIFGRLGFSIAEGPEIEDDWHVFSSLNFAEDHPARDMQDTFFIQHNPD
                     VLLRTHTSSVQTRVMEKQEPPIRIICPGRVYRNEAISYRAHCFFHQVEALYVDKNVSF
                     ADLKQALLFFAKEMFSPDTKIRLRPSYFPFTEPSAEMDISCNICGGKGCPFCKGTGWV
                     EILGCGMVDPNVLENCGIDSKVYSGYALGMGIERITNLKYQVKDLRMFSENDVRFLRQ
                     FESAN"
     gene            7667..8941
                     /locus_tag="ACZPB4_04730"
     CDS             7667..8941
                     /locus_tag="ACZPB4_04730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HIR1097561.1"
                     /translation="MEIVIIIGLILLNGILAMSEIALVSARKARLETEAKRGNKSAGT
                     ALKLANEPDKFLSTIQIGITLIGILTGLYSGEALAHNFAVIIAQIPALEPYALGIAKT
                     TIVIIVTYLTLIFGELVPKRIGMGCAEKVSMLVAKPMNFLSLISSPFVWLLSKSTALA
                     VKMTGVDTKEENRVTEEEIKAIVKEGFDGGEVQEVEQDIVERVFNLGDRNVGSIMTHR
                     SELVWLDVTDSTEKIREKVEENLFNIYPVASEKFDNIVGVVYLKDLFGRIDQPDFSIN
                     QVLRPAQFVPENQSVYNALESFKQTHVKYGLVTDEFGGIQGIVTLKDIMEGLIGQVPE
                     VGEESEIIQREDGTWLVDGQYSFYDFLEYFDMEDLYAEHDYNTLSGLILEILERVPKT
                     GEKLKWLDFEFEIVDMDGARIDKVLVKYLKNG"
     gene            complement(8951..9673)
                     /locus_tag="ACZPB4_04735"
     CDS             complement(8951..9673)
                     /locus_tag="ACZPB4_04735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0015288 - porin activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="porin family protein"
                     /protein_id="HIR1097562.1"
                     /translation="MKKVYLIGALLSFGLLAEAQSFMRFEDKAFNFGAKVGFNATFPV
                     INSLSINGKEAENIDIEYKVGYLAAVFCRVNIERFFLQPSFSWHRSEGNIRFSIPQSL
                     PENNMLSNTSATTDLLMMKTSSLEVPIMVGYNLVKKGPYGLSLMVGPKLKYNYKIAYT
                     VESSTTHVEYVNDNTPFGVNIATGVGVSIGRLFFDFVYEFGLNQVESDFEKVNNPVPE
                     INYDINIDKRTNVMSISLGVLF"
     gene            complement(9678..10244)
                     /locus_tag="ACZPB4_04740"
     CDS             complement(9678..10244)
                     /locus_tag="ACZPB4_04740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HIR1097563.1"
                     /translation="MKHDWKPGTMIYPLPAVMVSCGNEPSEYNIITVAWVGTICTNPA
                     MCYISVRPERFSYPILKKNMEFVINLTNRELAYATDWCGVNSGKDHHKFEEMKLTPGK
                     ATVVNAPTIDESPLCIECRVKEVIALGSHDMFIADVVNVQADDRYLDPETGAFDMQKA
                     DLLAYSHGKYYGLGEFVGKFGWSVKKKK"
     gene            complement(10336..10800)
                     /gene="pyrI"
                     /locus_tag="ACZPB4_04745"
     CDS             complement(10336..10800)
                     /gene="pyrI"
                     /locus_tag="ACZPB4_04745"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009347 - aspartate carbamoyltransferase
                     complex [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase regulatory
                     subunit"
                     /protein_id="HIR1097564.1"
                     /translation="MSAEKKKELQVAALENGTAIDHIPPSQLFKVASLLGLEKMNNTI
                     TIGNNFHSNKMGCKGMIKIADKFFEEDEINRIAMIAPNIILNIIRDYEVVEKKTVTLP
                     DELIGLVKCNNPKCITNNEPMLSRFHVIDKEKGTIKCHYCERKINKEDIIIK"
     gene            complement(10813..11733)
                     /gene="pyrB"
                     /locus_tag="ACZPB4_04750"
     CDS             complement(10813..11733)
                     /gene="pyrB"
                     /locus_tag="ACZPB4_04750"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase"
                     /protein_id="HIR1097565.1"
                     /translation="MKSKSLVSIDQCSKEDILRILDNARKFEENPNRKLLEGKVAATL
                     FFEPSTRTRLSFETAVNRLGGRVIGFSDASTTSSSKGETLKDTILMVSNYVDLIIMRH
                     HLEGAARYASEVTDVPIINAGDGANQHPSQTMLDLYSIRKTQGKLDNLTITMVGDLKY
                     GRTVHSLIVGMSHFHPTFHFVAPNELRMPDEQKNFCDKHGLKYEEHTDFTEDIINQTD
                     ILYMTRVQRERFTDLEEYERVKNVYILRNDMLRNSRENLRILHPLPRVNEIAYDVDDN
                     PKAYYIQQARNGLFARQAIICEVLGISIDE"
     gene            complement(11808..13508)
                     /locus_tag="ACZPB4_04755"
     CDS             complement(11808..13508)
                     /locus_tag="ACZPB4_04755"
                     /EC_number="3.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004035 - alkaline phosphatase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0106219 - zinc ion sensor activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase"
                     /protein_id="HIR1097566.1"
                     /translation="MKKTLAFLLLLAIIIMPANAVEKENVKPVKNVILLIPDGTSLAT
                     ISIARWLQWYQDPSKPKLNIDPYLCGTVRTHSSNAPIGDSAPTTSCYMTGQPSRTGYV
                     STYPENDGDNDIYPTDPARAFQPLTTVLEAGKMLQGKATGLVFTCEFPHATPADCSAH
                     SYNRGKYDWIAPQMVHNDIDVVIGGGVSILTKDMEDYLLANGYGVYRNDLKGMRADNN
                     QKMWALYGNKEMAYDIDRNPEEQPSIEEMTRKAIDKLSKNPNGFFLMVEGSKVDWAAH
                     GNDPVGMATDFLAFDRACGAALEFARNNGETAVVIVPDHGNSGISLGRKDCKGYDKLT
                     KDQLFHQFSLYKLTAEGFANKVNSVPNSEVQNVFRTYAGFELTPEEMNALNNCKDYKN
                     SPIPEDQRKPEDNSSMYSGSLTGLMAHIITSRTCFGFTTGGHTGEEVFLAAYHPQGTL
                     PLGMNTNIELNEYLCNLFGLTHGNLEDLTSKNFARHTDVFEDYTCEIVPAADEKGSPT
                     LIVKNKKDKKKQLTITPFSNIVKSGKKGQDEIRLNSVVVYVDKNNTFYLPASLVDFLK
                     "
     gene            complement(13552..14730)
                     /locus_tag="ACZPB4_04760"
     CDS             complement(13552..14730)
                     /locus_tag="ACZPB4_04760"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HIR1097567.1"
                     /translation="MISEELKNDLKIKWDRMRDGMAKMGMDACLLTVDVNLYYTTGQI
                     YSGYFYLPVDGEPWFLIKRPNGLSGHQVEYIRKPEDIPTLFAERGIKMPKRLLLEADE
                     LTYNEYIRLQKVFQPEEAGNATAFMRNLRRVKTPWEIGQFRIAARKHEATYSEIPECF
                     RPGMTDLEFQYEIEKRMRKNGSIGLFRAFGANMDIYMGSILAGENAETPSPFDFALGG
                     GGIDASCPLGANGTLLKEGTAIMVDMAGNYTAYMTDMTRVFSVGRLTEEAYRAHQVAL
                     TIQQEVENATRPGTACSDLYNIAANIAKKEGLSANFMGTEQQAKFVGHGIGIQINELP
                     VLTPRSKEELLPNMVFALEPKFVIPGVGAVGIENSFLVTETGVEKLTRFNEEIIPLGN
                     "
     gene            14866..15006
                     /locus_tag="ACZPB4_04765"
     CDS             14866..15006
                     /locus_tag="ACZPB4_04765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097568.1"
                     /translation="MNKDNHICIYSLILVVNPINHGVVFTDHGVVYKDHAVVCRIEVD
                     PI"
     gene            complement(15060..15509)
                     /locus_tag="ACZPB4_04770"
     CDS             complement(15060..15509)
                     /locus_tag="ACZPB4_04770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NanQ anomerase/TabA/YiaL family protein"
                     /protein_id="HIR1097569.1"
                     /translation="MILDSLENSKRIECIHPLFKQAFDYVKSTDFSKMEDGKYDIADA
                     GFTVSIASLFGKEKSEAAIETHKKFIDIQFPLLGVEKIGWKPGDQLLEESVPYNEEQD
                     IAFYIDKPTAYTKIYPGQFAIYFPEDGHAPGIGQGNIRKVVIKIPVQ"
     gene            15725..17938
                     /locus_tag="ACZPB4_04775"
     CDS             15725..17938
                     /locus_tag="ACZPB4_04775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HIR1097570.1"
                     /translation="MKDLETIILPVLEMSCAVCANNVENTVKGLPGVEEASVNFAANT
                     LSVKYHPSLITPQKMREAVQEAGYDLVVEVEDPTAVQEEMAREHYRKLRRNTIGAWVL
                     SIPLALLGMVFMHTPGGNWIMMALALVIMIVFGRSFYVNGVRHALHGSANMDTLVALS
                     TSIAFLFSFFNTVYPQFWYEKGLEPHVYYEASGVIIAFVLLGKLLEERAKNSTSSAIK
                     SLMGLQPKTARRVRDGQEEEVSISFLRVGDLVSVRPGEKIPVDGTVSQGSSSVDESML
                     SGEPIPVVKSQGDRVLAGTINQKGAFLMEATGVGSATVLSQIVQMVQAAQGSKAPVQR
                     IVDKISGIFVPIVVGLAILTFIVWLVVGGSGYFSYALLSAVSVLVIACPCALGLATPT
                     ALMVGMGKGAEHHILIKDAFALENLCKVDTVVLDKTGTLTEGVPEVTDSFWVSEASRD
                     MLDILYTAEMKSEHPLASAILSWLKGTEAAEIDADSFESVTGRGIQMQVHGVTYWVGS
                     KGFLETFKAMVPPEAGREIIRWEEDGKSIVYYGWESELLAVMAISDRLRPKSGEAVEA
                     LKEMGIEVHLLTGDGKRTAETVAAMLDIRHYKADVLPSDKEEYIRSLQAAGRKVAMVG
                     DGINDSQALARADVSIAMGKGTDIAMDVAMVTLITSDLMLLPDAIRLSKRTVRSILQN
                     LFWAFIYNLIGIPLAAGVLFPVNGLLLNPMLASAAMAFSSVSVVLNSLRLKWSKL"
     gene            17954..18160
                     /locus_tag="ACZPB4_04780"
     CDS             17954..18160
                     /locus_tag="ACZPB4_04780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HIR1097571.1"
                     /translation="MATLKFKTNAKCGGCVAAIGAKLNKLVKEDAWSIDLKSPDKTLT
                     ITTDLPAETILSAVSEAGFKASAL"
     gene            18178..18828
                     /gene="trhA"
                     /locus_tag="ACZPB4_04785"
     CDS             18178..18828
                     /gene="trhA"
                     /locus_tag="ACZPB4_04785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0019835 - cytolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PAQR family membrane homeostasis protein TrhA"
                     /protein_id="HIR1097572.1"
                     /translation="MRKQRQTHGEEVANVLTHGAGMLFGLTAIVVLMIAGIRTGDPWV
                     IGSFAVYALCMTSSYVTSTFYHAASDPKRKCQLRRWDHSAIYLHIAGTYTPFTLVALR
                     DEGFWGWGLFITVWLAAVIGVWFSFRRMKKKDNLKTVCYLLMSWVVIIAFKPLIDVFQ
                     RTDSMYVLYWLIGGGLFYSLGTIFFFLDKYKYMHSAWHLFVLGGTVCHFIAIYNLV"
     gene            complement(18909..20228)
                     /locus_tag="ACZPB4_04790"
     CDS             complement(18909..20228)
                     /locus_tag="ACZPB4_04790"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TldD/PmbA family protein"
                     /protein_id="HIR1097573.1"
                     /translation="MITNENKKLAQWAMEYALKNGCQSSRVTLYNGSSSSFEIRDMKI
                     DRLQQASENSMVVHLFVDGRYGSYSTNRLDKKELEKFIKDGISATRFLAEDKARTLPD
                     ASLYYKGGAADLRLVDPNFDSVQPDDKVALAMSVCEEIMGKDDRIISANASYSDEKDF
                     KYMVASNGFEGEASGSSYGLVGSVSIRGEGDARPESYWYDSSLYYDELVKTGIGTKAL
                     ERVLRKLGQRKVASGKYTMIVDNMNSSRLLSPVIGAIYGSSIQQKNSFLLDKIDQKVA
                     SDKMTLIDEPHLVKASGARYFDSEGVATKRLPVFEQGILKTYYIDTYSANKMGMEQTI
                     GSPSILTMRNGDKDLDGLIASIDKGILVTGFNGGNCNSTTGDFSYGVEGFLIERGKLS
                     QPISEMNATGNMLSLWSNLAEVGNDPRLSSSWRIPSLLFNGVDFSGL"
     gene            complement(20230..21762)
                     /locus_tag="ACZPB4_04795"
     CDS             complement(20230..21762)
                     /locus_tag="ACZPB4_04795"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TldD/PmbA family protein"
                     /protein_id="HIR1097574.1"
                     /translation="MNINRRDFIKTGGMVMLGTLAAPSLLGSCTGSEGDKAAGISFAM
                     NYFKVSEGDLRKVLAAALEKGGDYADLFFEHSYRNNVGLQDGAVNRASSNIDFGMGVR
                     VLAGDQTGYAYVENVTLDEMLKAARTAARIATGSANTTAINLTEKACTNNFYSVQTPW
                     DEIAINDKMPFLQKLNDQIFAKDKRVTKVMASLGDTTSHILFCNSEGQIYYDYRPMSA
                     LSAVCIMEDNGKIENSYAARAFRMGAEFLTDDLIDELAQEAVDKTSILFQAIKPKGGE
                     MPVVMGAGGSGILLHEAIGHAFEADFNRKNTSIFSDQLNKKVCNEHINVVDDGTIPFN
                     RGSVNIDDEGVDGQKTYIVREGVLTSYLHDRISAKHYGIPSTGNGRRESFRQMPIPRM
                     RATYMEAGNVTEEEIISTVKKGIYAANFTNGQVQIGAGDFTFFVKDGYLIENGKLTQP
                     IKDINIIGNGPKALADITMVGNNYKMDNGTWTCGKDGQSCPVTCGMPSALVSKLTVGG
                     EN"
     gene            complement(21752..22993)
                     /locus_tag="ACZPB4_04800"
     CDS             complement(21752..22993)
                     /locus_tag="ACZPB4_04800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfatase-maturation protein"
                     /protein_id="HIR1097575.1"
                     /translation="MNSSYISPFAKPVYIMLKPIGSVCNLACEYCYYLEKSKFYPDVK
                     NHIMTDQILEKFIKEYMECQTMQEVLFTWHGGETLMRPISFYKKALELQRKYAGGRQI
                     DNCIQTNGTLLNDEWCQFFKENNFLVGVSIDGPQEFHDEYRRNRQGLPSFYKVMKGIE
                     LLKKHGVEYNAMAVVNDYNVDYPLEFYNFFKELDCRFIQFAPIVERIGRHKEGTKLSS
                     PEEQNAAIELASFSVDSEKWGDFLCALFDEWLKEDIGKFYIQLFDSTLANWVGEQPGV
                     CSLARHCGHAGVMEFNGDVYACDHFVFPEYKLGNIQTKTLTEMMYSPVQQKFGTDKED
                     KLPTQCKECEYLFACHGECPKNRFLHTPNGEPGLNYLCKGYKKFFKHVAPYMDFMKKE
                     LLNQRPPANVMDWAKQQQHEY"
     gene            complement(23018..24784)
                     /locus_tag="ACZPB4_04805"
     CDS             complement(23018..24784)
                     /locus_tag="ACZPB4_04805"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArnT family glycosyltransferase"
                     /protein_id="HIR1097576.1"
                     /translation="MRTPTLQYLYLQKPVTMMVVICIISVLPWIGLGDFSTKGEPREA
                     AVAISMLETGNWVLPQSYANEFAFKPPMAHWLMAAFSYPQGYVSEFTSRLPSALAFIT
                     LIGFVLVFFGKRIVKFQEAFIATLLLVTCVEIHRAAMTTRVDMLLTTFIVIGLFQLYR
                     WEDKLELKGLPIFIPLLLGCAVLTKGPVGVVLPLFVFGIYLLMLGQYSYLTIFKTLLY
                     AGISSLFLPMLWYTAAWKQGGDEFLNVVLAENFARFLHLNTPEISYDLGHENGVWYNF
                     MTLAAGFIPWTIFFFFSLFGLKLSKPEQPIKEILKNTWKRIRSMEKVRLFSLVALIGI
                     LFFYSIPSSKRSVYLMPAYPFIALFLAQYALYITEYRTKVTRVFAAFLASVVSVVMIA
                     ILLTVFGIIDPVGIVGQYTQNASTLDMVRMVSKVLVHPSTLTICIIFINLLILGTVYY
                     QMFKKINIKILYATIALTFSVNLLIDGVIMRGIREGDSCRVFAERILKEYPLNKKNVY
                     VVNNLRIYRNLYGLNFYMGNIFHDFDKETPAKGYFLIGENEMEKVLSTYGDKYTFRTL
                     TKSDQTFSELKQKIVLSEFELK"
     gene            complement(24883..26439)
                     /locus_tag="ACZPB4_04810"
     CDS             complement(24883..26439)
                     /locus_tag="ACZPB4_04810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4435 domain-containing protein"
                     /protein_id="HIR1097577.1"
                     /translation="MELTLPTKVNVTHPIMLDTKILVVIGANGAGKSSFGRDLLERYA
                     GQAKRISGIHALFISDDESKLSASNEFARLQSMIKERLFMPRISEYEKLILQLQSEEF
                     EAAVNFKEACKTNNEVDPPITKIDIIQAIWEKMFPHNRLIRKSGFIELVSTGRDSNSY
                     TAGRMSDSEKLVFYLIGAALCACPNALLVIEEPETLLHNSIKNQLWDEIEAIRPDCTF
                     VYLTHDIDFATSRSDSKRIWIRSYDADHSVWDYELIESNESFPEEVYMEILGSRKPIL
                     FIEGTDTNSIDSKLYPFIFPDYLVKPMGGCQKVIETTKAFGQLKDFHTLDSKGIVDRD
                     RRTQGEINYLREQHIYVPDVAEVENLLMIEDVIKTVAKRLMKDPDDVFKQVKENVVRL
                     FQKELDSQVILHAKHQVRKKLETTVDRKITTVEQLTEHVESIRLNIHVEEIYKNIKEE
                     FESYIETENYKSILRVYNQKGMLPQSRLCAICGISNKESYLNLILSILKENKEDAEAI
                     RKAIKHSLGT"
     gene            complement(26578..26790)
                     /locus_tag="ACZPB4_04815"
     CDS             complement(26578..26790)
                     /locus_tag="ACZPB4_04815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097578.1"
                     /translation="MARTVDYSKKAEKIKEQVDELVQELMAAKSAPVVSKRSLKVADI
                     NFENEDVNTLMQIQARLARVILEKSK"
     gene            complement(26951..28438)
                     /gene="gadC"
                     /locus_tag="ACZPB4_04820"
     CDS             complement(26951..28438)
                     /gene="gadC"
                     /locus_tag="ACZPB4_04820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative glutamine/gamma-aminobutyrate
                     antiporter GadC"
                     /protein_id="HIR1097579.1"
                     /translation="MANINKTVKLGVFTLAIMNVTAVVSLRGLPAEAVYGLSSAFYYL
                     FAAIVFLIPTSLVAAELAAMFQDKQGGVFRWVGEAYGKRLGFLAIWVQWIESTIWYPT
                     VLTFGAVSIAFIGMDHPEDMLLANNKYYTLAIVLIIYWLATFISLKGLSWVGKVAKIG
                     GMVGTIIPAALLIILGIVYLATGGHSNMDFHSNFFPDFSKFDNLVLAASIFLFYAGME
                     MGGIHVKDVDNPSKNYPKAVFIGALITVVIFVLGTFALGIIIPEKDINLTQSLLVGFD
                     NYFKYIHASWLSPIIAIALAFGVLAGVLTWVAGPSKGIFAVGKAGYLPPFFQKTNKIG
                     VQKNILYIQGAAVTLLSLLFVVMPSVQSFYQILSQLTVILYLIMYMLMFSGAIALRYK
                     MKKAGRPFRIGKGGNGLMWLIGGLGFCGSLLAFVLSFIPPSQISTGNNTVWFAVLFIG
                     VIVVVAAPFIIYASKKASWVDPNTEFEPFHWEVKNDVSETNTTKA"
     gene            28636..29382
                     /locus_tag="ACZPB4_04825"
     CDS             28636..29382
                     /locus_tag="ACZPB4_04825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005216 - monoatomic ion channel activity
                     [Evidence IEA];
                     GO_function: GO:0005267 - potassium channel activity
                     [Evidence IEA];
                     GO_process: GO:0034220 - monoatomic ion transmembrane
                     transport [Evidence IEA];
                     GO_process: GO:0071805 - potassium ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
                     /protein_id="HIR1097580.1"
                     /translation="MKMAVFDFALRKKGVYGVLHIIILLLSLFLVISISIDTFKNIPF
                     YTQTSYKKIQLWICLFFLFDFVLEFFLSKDKLRYLRTHFIFLLVAIPYQNIIEYYHII
                     TSPELSYFLRFVPLVRGGYALAIVVGWLSYNKASGLFVSYLTMLLATVYFSSLIFFVL
                     EHKVNPLVANYGDALWWAFMDVTTVGSNISAITVTGRVLSVVLAALGMMMFPIFTVYV
                     TSLVQKSNEEKKRFYENMQAPSPQPEVKDK"
     gene            29539..32394
                     /gene="uvrA"
                     /locus_tag="ACZPB4_04830"
     CDS             29539..32394
                     /gene="uvrA"
                     /locus_tag="ACZPB4_04830"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HIR1097581.1"
                     /translation="MIKDKQALEGGRISILGARVHNLKNIDVEIPRNKLTVITGMSGS
                     GKSSLAFDTIFAEGQRRYVETFSAYARNFLGNMERPDVDKITGLSPVISIEQKTTNKN
                     PRSTVGTTTEIYDFFRLLYARAGEAYSYLSGEKMVKYTEDQVLRLILDEYNGKKTYLL
                     APLVRNRKGHYKELFEQIRKKGYLNVRVDGELKEIFHGMKLDRYKMHSIEVVIDKMIV
                     SEADERRLKESLKIAMKQGDGLVLILDAETNEVRHYSRRLMDPVTGLSYSEPAPHNFS
                     FNSPQGACPKCKGLGQVNLLDMDKIVPDPSLSIYSGGIVALGKYKNSLIFWQIEALCQ
                     KHGVTIKTPIRDIPEEAMDEIMNGTDERLQIKNDSLGSSNYFLSYEGVAKYILMQQES
                     EASASAQKWAGQFIKMATCPECNGWRLNKEALSYRIAGKNIAELSAMDISELYEWLEG
                     IEEKLDPKQLRIATEILKEIRSRLRFLLDVGLDYLSMNRGSATLSGGESQRIRLATQI
                     GSQLVNVLYILDEPSIGLHQRDNVRLINSLKQLRDTGNSVIVVEHDKDMMLSADYVVD
                     MGPKAGRLGGEVVFEGTPKEMLRVDTLTSSYLNGNTEIAVPAERRKGNGQFITIKGAS
                     GNNLKHVDVSFPLGTLICVTGVSGSGKSTLINRTLQPILSQHFYHSLEDPLAYDVIEG
                     IEHVDKIVNVDQSPIGRSPRSNPATYTGVFSDIRNLFVELPESKVRGYKPGRFSFNVS
                     GGRCETCKGNGYKTIEMNFLPDVLVPCEDCHGKRYNRETLEVRFRGKSIADILDMTIN
                     MAVEFFENIPTILSKIKVLQDVGLGYIKLGQPSTTLSGGESQRVKLATELAKRDTGKT
                     LYVLDEPTTGLHFEDIRVLLGVLNKLVDKGNTIIVIEHNLDVIKSADYLIDMGPEGGR
                     RGGNVLFTGTPEALAKSGVGFTAPFLKEELDIANKKK"
     gene            32391..32612
                     /locus_tag="ACZPB4_04835"
     CDS             32391..32612
                     /locus_tag="ACZPB4_04835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007658121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097582.1"
                     /translation="MKNPIQMIKQCVEKEEPYFVLRGQDVCALAAIETYYEEVRNKVK
                     DPYFIEEIEEIMKDFRAYREEVSNTKIPD"
     gene            32616..33215
                     /locus_tag="ACZPB4_04840"
     CDS             32616..33215
                     /locus_tag="ACZPB4_04840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMPACT family protein"
                     /protein_id="HIR1097583.1"
                     /translation="MADDSYKTIKQVAEGYYTEKRSRFISYAIPVRTVEEVKEQLEKY
                     RKQYYDARHVCWAYMLGPERQTFRANDDGEPSSTAGKPILGQINSNELTDLLIVVVRY
                     FGGIELGTSGLIVAYRTAAAEAIAAAEIEERTVDEDITVVFEYPYLNGIMRIVKEDNP
                     AIISQKFEMDCEMTLRIRKGEAERLKNRLLKVETAYLKE"
     gene            33323..34531
                     /locus_tag="ACZPB4_04845"
     CDS             33323..34531
                     /locus_tag="ACZPB4_04845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HIR1097584.1"
                     /translation="MKKVLLFSFFLVLGLVVSQMLPAMVGEQYSLVKTISNTFLFICL
                     AFIMINVGREFEIDKTRWKSYTEDYFIAMATAAFPWIFVALYYMFVLLPGDLWGSWDA
                     WKENLLLSRFAAPTSAGILFTMLAAAGLKASWVYKKVQVLAIFDDLDTILLMIPLQIM
                     MIGLRWQLGVIILVVVLLLILGWKKMGYYNVRQDWKAILFYAVVTFGITQVIYLVSKH
                     MYGEEASIHIEVLLPAFVVGMIMRHKHIDTKIEHQVSDFISYLFMFLVGVSMPVFMGV
                     DFAQQAAEVTTVTGSQPMMSWSMIALHVVIVSFLSNIGKLFPLFFYRDRMKRERLALS
                     IGMFTRGEVGAGVIFIALGYGLGGPMLIISVLTIVFNLILTGIFVIWVEKLTRSAYNL
                     EQAGKAKAVN"
     gene            34645..36006
                     /gene="nhaA"
                     /locus_tag="ACZPB4_04850"
     CDS             34645..36006
                     /gene="nhaA"
                     /locus_tag="ACZPB4_04850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006885 - regulation of pH [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaA"
                     /protein_id="HIR1097585.1"
                     /translation="MDRTINVILKPLRRFAIQKPNASLLLFAATIVAMVLANSPWADR
                     YHQLLAFPIDLQAGQFNFFAHHGETMSMLAFVNDALMAVFFFVIGLEIKQEVLIGELS
                     SVRKALLPIIAACGGMIVPVLFYMLVCNTPPEVNGAAIPMATDIAFALAVLGLLGKRV
                     PLSMRIFLTALAVVDDIGGIIIIALFYSGHIAFEPLLISLIVLALLYVGGKFRVHNRL
                     FFYIGGFIVWLLFLESGIHPTIAGVLIAFTVPARPVVKLDDFTCDMTGYLNMLDYTEV
                     RQSRKAEVLTPTQIQVLNNIHTLADKTISPLQTIADKLHPLVNYVILPLFAFVNAGVT
                     FGDIQPQTLVNVPLAVFVGLFVGKTLGIFSFSYLFACTPFASMPTGMSKRNLFGVSML
                     GGIGFTVALFIANLSFDGSTAAGADLLNQAKLGVFTGSFISGLCGYLVLKWVLPKEKV
                     ETI"
     gene            complement(36119..36370)
                     /locus_tag="ACZPB4_04855"
     CDS             complement(36119..36370)
                     /locus_tag="ACZPB4_04855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HIR1097586.1"
                     /translation="MGFIWSIIIGIVAGYLAGKIMRGGGFGVIVNLILGIIGGVLGGW
                     VFSLLGISAGGILGSLITSTVGAILLLWIGSLFNKSKEV"
     gene            complement(36468..37928)
                     /locus_tag="ACZPB4_04860"
     CDS             complement(36468..37928)
                     /locus_tag="ACZPB4_04860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase family glycosyl hydrolase"
                     /protein_id="HIR1097587.1"
                     /translation="MLRREMRLVLDLVVNHTSDEHPWFEEARKSRHNPYYNYYHWWPA
                     EKGEPPLRLSYFDEEGNAWTYNKPTDSYYLHYFSRKQPDLNWENPEVRQEIFDMMRFW
                     FDKGIDGFRMDSISLIAKDPSFPLIDSKKYPDIFSFYAKEPRLHLYLHEMNRQVLSKY
                     DCMSVGEGSAVMVDDVAKFVDPAREELNMLYHFDAARIRNTTLPDNPESGIDYSLIAL
                     KKMFTEWDKAVDKGWPSIYLGNHDQPRMVSRFGSDKDEFRALSAKMLITFLLTMRGTP
                     YWFAGDEIGMRNIRFDHIEDYNDIDTINRYKKAKAEGKDPQAVLDEQKETGRDNARTP
                     FQWDRSPEAGFTAGTPWLKVNPDYTWINVADEEKDPTSILNYFKKVVSFRKENPSLIY
                     GSYHLLDAENPQSYTFLRKTGADTYLIMLNFSPKAAISTPGIDMSNAHVLLDNYGDRS
                     HMAPQKDITLRPFEAIVFQLNHPVYESFIDSLDLLE"
     gene            38541..38816
                     /locus_tag="ACZPB4_04865"
     CDS             38541..38816
                     /locus_tag="ACZPB4_04865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009135239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097588.1"
                     /translation="MDKRNKLWRRQQMARVFKTRMILYAAYGHCIIREDGSYYEHPHW
                     FELAKDKWAQVYKTTGTPCSCWMCRGFEYDRKEYKKETLRIIRESME"
     gene            complement(38918..39430)
                     /locus_tag="ACZPB4_04870"
     CDS             complement(38918..39430)
                     /locus_tag="ACZPB4_04870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6155 family protein"
                     /protein_id="HIR1097589.1"
                     /translation="MSKAKLKKHLLSLTKEQITDIVLELYDARKEAKDYLEFYLAPDC
                     NAELEKSKKAIRNEFFPTRGFSEKPSFAKCRKVISDFQKLKPEPTTVADLMLFYIEQG
                     CEYTLEFGDMWEQFYTTLEGNFDKAMRFIFLNGLLACYYERIEKLIDSVSDCGWGFYD
                     TLQDIYSEYR"
     gene            complement(39522..40349)
                     /locus_tag="ACZPB4_04875"
     CDS             complement(39522..40349)
                     /locus_tag="ACZPB4_04875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007831972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HIR1097590.1"
                     /translation="MGKTVTTYLIDGDPKGTQYAFISNKICQMFVVPRSNLSYLNTQE
                     KLQKPAFYILLGEDESTKPQAYIGETENFKERVKDHDSKKAFWQKALIFVSKDADMTK
                     VDVQYLEHKAIAEAKKANAFVLSDNKQIPKAPNLPEHQQDSMDEFFEDVKFLASFIGC
                     NIFDVSQPKEEHLFYTKGRGCNAKGFYSSDGFTVLKGSTVAKTMVPSFNWKEKREKML
                     QDYTSTENGILVLTSDKTFSSPSTAADFCIGSSNNGWLIWKDKDGNTLDSVYRKQLD"
     gene            40543..40746
                     /locus_tag="ACZPB4_04880"
     CDS             40543..40746
                     /locus_tag="ACZPB4_04880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005682081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIR1097591.1"
                     /translation="MKLNKIKTVLSDKGISQTWLAKQLDKSFSMVNAYACNRIQPNLE
                     TLQRIAEILQVDLKDLITDKEER"
     gene            40753..43917
                     /locus_tag="ACZPB4_04885"
     CDS             40753..43917
                     /locus_tag="ACZPB4_04885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease"
                     /protein_id="HIR1097592.1"
                     /translation="MKNFTENTRVQVPAALHLCKLGYTYLDDLTSYNPQTNILTDIFI
                     RSVKRLNPALTDLECSQLLDKIVGILNNDDLGKEFYTMLSSNSGVKLIDFADANNNEW
                     HVTTEFTCENVESGDSFRPDITCFINGLPLAFIEVKKPNNHDGILAERDRINKRMRSK
                     SFRRFINLTQLMIFSNNQEYDNENRVPIQGAFYCCAAKERAFFNVFREADATFVSKYP
                     YLALTEDSEKQVLKHRNCIVIKNLPDYETNKKVDTPTNRVLTSMLCRERFLFLLRYGF
                     AYVNRTIELEDGSKITTLEKHVMRYQQLFASLAIRKKLSKGVKSGIIWHTQGSGKTAL
                     AYYSVRSLTDYYAKRETAVKFYFIVDRIALMEQASDEFVARGLVVRNVNSRDDLMKDI
                     RDTTPVVNSEGKAEIMVVNIQKFKEDSTKIQIESGYNTNLQRVFFIDEAHRGYSPQGS
                     FLANLLEADKDAVKIALTGTPLLREEKESWRVFGDYIDTYYYDKSIADGYTLKLMREP
                     IETIYKERIESILDKLAGNVEVKKSDIDKNKIIEHESYLNALLDYIISDLRRFRKEQA
                     DDSIGAMIVCKTNPQAREMFRLWQQRFRFAQRIEDKWEEQLGMVAEPMVAYGHAKPLR
                     ASLILHDEGDKLERKAYIEEYKKQQTVDVLIVNQMLLTGFDAPRLKKLYLGRSLDGHD
                     LLQALTRVNRPYKDFKYGYVVDFVDIKENFDSTNDRYLRELNRTADIKEIQQDEPVGN
                     AIIEDKEEIIAKMKEIKSILFNFTCDNPEEFRQEIDEIEDKDRLYELRSVLNDAKAIL
                     NQVRAFGDDELKEKIESLAFGGIPTLVTEVTHRIERMNLFESTEHKADVAGIINVALS
                     ELEFEFKKGISEELRIVVNDIRERCEKVQTEFDANFDRNEEKYVILADEFRAYFRKKG
                     FVPQNTQDAKDSIDYMDNVMKKIREINRRNNILKKKYKGDERFVRIHKRIEEENQKRE
                     QPIISAHEYEIAENLSQMKSQIDNMLFLNINVLDNEDAFKRDVLAIIGRKLIDLGIKA
                     NLTDRKYINNLITTEYFQQRNFAY"
     gene            43920..45596
                     /locus_tag="ACZPB4_04890"
     CDS             43920..45596
                     /locus_tag="ACZPB4_04890"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005795766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HsdM family class I SAM-dependent
                     methyltransferase"
                     /protein_id="HIR1097593.1"
                     /translation="MSDINITESTIALIDSLKSTTGAFGLAGTGSEYKIVTEMFLYKF
                     FNDKFGYEAKRDKMYGERLSKAEKWDAEYDTFTEEEVEDLFSYLPASVPRLKPEHTLS
                     HLYNFTGKGDFSTLLDATLIDIANINADTFSVTTSGKSKVNIFSAITTFVTDQQKRDE
                     FAKSLMRNVASFNFEHVFIEKYDFFSRIFEHLLKGFNNAGGGKYAEYYTPRAIAQVMA
                     RLLVGDNADLRGVTCYDPSAGTGTLLMALAHQIGEDRCSIYSQDISEKSSEMLRLNLI
                     LNSLSASLPNVVQGNTLTEPSHTELSGALKKFDFIVSNPPFKLDFPEYRDTLAADTIR
                     FWAGVPNKVKKINPEKPQMGIYLCFLQHVINSLKDTGKSAVVVPTGFITSKKRNNVVA
                     YNILQKIVDEHIVCGCISMPTNVFATTGTNVSVIFFDKSATADKVILIDASKLGEEYK
                     EGNNQKRRLLDNEIDLIVNTFRNKEVVEDFSVAVSYDEIKEKGYSLSAGQYFDIKIDY
                     VDITEEEFNNRMANYKQILSEQFKESHRLEEEIMKQLDALQFNENVGNNE"
     gene            45589..46590
                     /locus_tag="ACZPB4_04895"
     CDS             45589..46590
                     /locus_tag="ACZPB4_04895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008861740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence RhuM family protein"
                     /protein_id="HIR1097594.1"
                     /translation="MSNEIQFLLYNLPDKEGRVQVVIKDETIWCTQKAMAELFGIDKS
                     GISRHIANIFREEELQQDTTVAKIATVVNRGIRGEVEELVDFYNLDMIIAVGYRVSSP
                     KATKFRQWATKILNEYIKKGFVLDDERLKQGTAVFGKDYFRELLERVRSIRASERRIW
                     QQITDIYAECSIDYDKNSPTTHDFYAMIQNRFHYAITGQTAAEIIYTKADHTQEHMGL
                     TTWKNAPDGRILKSDVSIAKNYLQENEIRRLERVVTGYFDYIEDLIERENTFNMEQFA
                     ASVNEFLTFRKYQILPDKGRISAAQAKTKAESEYDIFNKTQRIDSDFDKEVRGMLGE"
     gene            46603..47028
                     /locus_tag="ACZPB4_04900"
     CDS             46603..47028
                     /locus_tag="ACZPB4_04900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097595.1"
                     /translation="MTEDEKLIQEVQDQCEYFAKGIINSLCKRAIRKINSWNIHIGTD
                     DYPSSFNFFNILSIEYQSKCYDEISPCLEDAIEGVLDNEYEKLLPQERFFVDYSQCYY
                     DNEFDSESIKRKIYDRFYEILNEHWESKKIANFEEKRNW"
     gene            47065..>47395
                     /locus_tag="ACZPB4_04905"
     CDS             47065..>47395
                     /locus_tag="ACZPB4_04905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097596.1"
                     /translation="MTEIKEFLKSETKISKDCRVKYWLFCKILDYLLANQFYIGKDYV
                     SYKDIHTYLDKQCTFDYIDSIHAQTELWVHEMLWLGLINFDENSQQMSLTPEGALPGF
                     AFTKAVNS"
BASE COUNT        12885 a         9708 c        11194 g        13608 t
ORIGIN      
        1 gttcaattcc cggcgggagg ttccatcacg attatcgccg taacgacctt atccggtggt
       61 gatatcacgc atgccgtacc tgataatacg ggttatatca cggaaggtca gttgtatttg
      121 cgtcgtgata gcgatgtggg taaggtcatc gtcgatccgt tccgaagctt gtctcgtttg
      181 aaacagctgg taaccggaaa gaagacccgt gaggatcatc cacaggtaat gaacgccgcc
      241 gtacgtttgt atgccgatgc cgccaacgct aagaccaagc tggagaatgg tttcgacttg
      301 accgactacg acaaccgtac cttgtctttc gccaaggatt attcttctaa gctgttggct
      361 atcgacgtaa acttggatac gacggagatg ctggacgtag cttggggatt gttcgctaga
      421 tatttcagcc cggaggaggt aaatatcaaa caaggattgg ttgataagta ctggaagtaa
      481 attaaataaa catggcaata aagtttcaat ataataaaac ctctcttcag caattggaaa
      541 agcaactgaa gatgcgtgaa cgctccctgc ctacgatcaa gagcaaggag agcgccctgc
      601 gtatcgaggt gaagcggacc aaggacgaag tgaataaatt ggaacttcag ctagaacgag
      661 agattcagag ttacgagaat atggtggctt tgtggaacga gttcaatccg gagctgatct
      721 ccgtgaagga cgttacgctc tccacgaaga agatcgccgg cgtgatcgtc ccgttattgg
      781 acgagatcaa gttcgagatc ggacactata gtctctttaa tgcccccgca tggtatacgg
      841 atggtatcga gttgctgaaa aagctggctc gtaccggtat cgaggcggag ttctcgggca
      901 tgaagctgga gttgttggag catgctagga aaaagaccac tcagaaggtg aacctgtttg
      961 agaaggtaca gattccgggt tataaggatg cgatccgtaa ggtgaaacgg tttatggaag
     1021 acgaggagag tctttctaag tcctcacaga agatcatgag agccaatcag gagaaacgta
     1081 aggcaaaaga agaaaaagag gaggccgagg tatgatagta aagatgagta aatatgcctt
     1141 tatggtgtac cataaggagt atgatacgtt cctttctacg cttcgtgact taggtgtcgt
     1201 ccatatcaag gagacaaact ccgtgatgga taacgagagg ttgcaagagc ttctggctga
     1261 gcgtaaacag atcaatacgc tgatgcgtta ctttaagaac ctccatgcgg cggagaaaga
     1321 cgttaagttt gccccggccc gtgagttgac gaaagaggaa ggcttgaagt tggtgcgtaa
     1381 gatagaggaa ttgcaagata agaaagcgca attgatcgct tccaagcaat cgatcgagaa
     1441 ggatctggct tatatggaaa tatggggtga gttcagttat cagaatatca accgtctgaa
     1501 aagagcggga tacgatgtta cgttctttac ctgtcctact gctaagtacg agccggaatg
     1561 gggcgtgctg tataacgcca ttctgatcaa taacttccaa tcggtaacgt attttatcac
     1621 gattaccaag gaaggtacct tgatcgatat agacgctgaa cgtccgaaga tgccggttca
     1681 aggattggcg aagttgcgtg cccgtctgga tcaacgtacc aaggatatcc agaatgtgga
     1741 ggatgagctg aaacatcgtg ccgtggggga ttataaaacg ttggaggaat tcgataagaa
     1801 cctgcaggac gagtttaatc tttctaatgc gttagtgcag acagatcggc aagcgggtga
     1861 taagctcatg ttgttggaag gttgggtgcc gacggaaaac gctccggcct tggagcacga
     1921 gctggataag caaggttatt tcttccagca attagagatc gaggatgggg ataaggtgcc
     1981 tatcaagcta cggaataata aattcagtaa gctgtacgag cctatcacga agatgttctc
     2041 cttgcctaat tacggtgaac ttgatccgac cccgttgttc gccccgttct ttatgctgtt
     2101 cttcggactt tgtttcggcg atggcggata tggtttgctg gtcatgatcg cttgtacgat
     2161 cttgaagaag aaggtgaacc cggatttcaa gccttatttg accttgttcc agtatttagg
     2221 cttcgccgcc ttattggtgg gtacttgtac gggatctttc ttcggagtgg ccttggcgga
     2281 tatcccggct ttgtcaaaga tcaagaacta ctttgtgaat agcgacaact tgatgacatt
     2341 ctctattgtc atcggtttgg tacagatcat attcggtaaa tgtgtcgctg cttacaagat
     2401 caagatacag aaaggaacga aacacagtat cgctccgttc gcttgggtgt tcgtgatcat
     2461 atccttggca ttggcgttcg gacttccgat gttaaacgtt cacttgccga acgctgtcgt
     2521 tatggtatgt tacggaatcg ccatcttggg tctggttgtc gcttatttgt acaatacacc
     2581 gggcaagaac gtattcttga actttggtac cggactttgg aacacgtaca atatggcctc
     2641 cggattgctg ggggatacgt tatcatacat tcgtttgttc gctatcggtc tgaccggttc
     2701 catcttgggt ggcgtattta atacgttggc ggttacgatg acagacggta tgaatatcgt
     2761 ggcacgtgcg atctgtatgt tgttgatctt gttagtgggt cactccatca atatcgctct
     2821 ttgtacgatc agctccttgg tacacccgct tcgtttgatc ttcgtggaat attacaagaa
     2881 cgcggagttc gaaggtggag gtaaggccta tgagccattc agaaaagcat aacaattaaa
     2941 cgagaaaata aaacaataaa agaataattt aaaaacacat tttattatgg aaccaatttt
     3001 attagcttat gtaggtattg cgttgatgac aggtttaact tttatcggca gtagttatgg
     3061 tgttacgatc gcaggtaatg cggtggtagg tgcgatgaag aaaaatccgg atgctctggg
     3121 tacgtacatc gctttaagtg cgttgccttc ttcacagggc ttgtatggat tcgtgggcta
     3181 ctttatgatg cagaagttct tggtcgctga tatttccatg ttggctgcta cggctgtttt
     3241 cggcgctggt ttagtgttag gtttcgctgg tttttactct tcaatccgcc aagctcaagt
     3301 ttgcgcgaat ggtatcgctg gtgttggtgc cggacacaac gtattcggtg ctacgatggt
     3361 aatggccgta ttcccagagt tgtacgctat cttggcctta ttggttgtga tcttgattgg
     3421 cggaacgatt cctgtcgcct aatcattcaa acatctggat ataatagagg ccgtcccgga
     3481 cattcccggg gcggtttttt tgattggatc aatgaataaa ctatctcttt tagtttatta
     3541 actatacaaa ttagtttggt aactaaaagt tttagttact ttgtcgcaaa caagataagg
     3601 ttatgaaacg acttacggtg aaagaagaag aaatcatggg ctggttctgg cagaaaggcc
     3661 cactgttcgt gaaagagtta cttgaatatt acgaggagcc taaacctcat ttcaataccc
     3721 tttctacgat tgtccgaggc ttggaggaga aaggtttcct cgcccataag aatttcggga
     3781 atagctatca atattatgcg gtcttaacag aaaaggagta tagtaacggt actttgaaaa
     3841 atgtgatcgc taagtatttc aataattctt atctgggggt tgtctctacg ctgatcaagg
     3901 aagaggatat ctctgtggat gatctgcgaa aactaataga tgatgtagaa caagggaatc
     3961 gtaaataaga gcgaatatgg gaatcttctt tgtatatatc cttaaatcat ccgtgtgctt
     4021 gacgatattt tatctgtttt ataagctatt gttgagccgt gataccttcc atcgtttcaa
     4081 ccggatcgct ttattaagct tgatcatgct ttcggttatc atcccatttt gtgagattac
     4141 tttggagaaa gcgacggcca ttcagcgtcc ggtcatggat ttggagaatt tgctagcggc
     4201 ggtttccatg agaacgtcgg cagaatccgc tagccaacct gtatggttac gagttatggt
     4261 gatagcctat ataatcggag ggatattaac gctttgtcaa ttcgcatatt cattttatgc
     4321 cttgtttcgg ttgatgagac aaggtacacc gaagctggtg gacggaatcc atctgattct
     4381 tacggaccaa ccagtcgccc cgttcagttg gatgcaaacg atcgtaataa gccggaagga
     4441 ttttgaggaa agtgggatag agatcatgac gcatgagatg gcgcatataa aagcccgtca
     4501 ttccattgat ctgctgatct ccgagatttg tatcctgttc cattggttca acccatctgt
     4561 ctggttgttg agacaggaat tgcaaaatat ccatgaatac gaggccgacg agagcgtatt
     4621 aaatcaaggc gtcgacgcaa aaagatatca attattatta attaaaaaag ctgttggtgc
     4681 acagcgcttc acttctatgg ccaacagctt taatcacagt tcacttaaaa agcgaatagc
     4741 tatgatgtta aaacaaaaat caagtccatg ggcacggttg aagtatctgt atgtactccc
     4801 gttggcagcc ttaacggtgg tagcctttgc ccgtccggaa atctctcacg aattggagaa
     4861 gatttcgagt gtcaaaatta gcgaaattat tccggttcag gaaaaaaaag agcctaaaag
     4921 aaatgtagaa gttgagaccc tcgcaaggga ttcggtcgtt tctgaaaaag atatgcaagc
     4981 gatacaggaa aaggtctcgg ccgtgatgga gaaataccag ccggagattg acaaggcggt
     5041 tgaagaggca gtgaaagcgg cgaatatcga cgagatcgtt tctgcggaaa tggcgaaaca
     5101 ccaggctgag atcgacaagg ctgtgcaagc ggcgatagag gccgccaaga taaatgagac
     5161 tatcgccgcc gagatggaga agattcaacc ggagatcaac cgagccatag aggaggccat
     5221 gaaagccata gacatcaatg agaaggctgc taaggaggca tcaaaggaaa agtcctcttt
     5281 ctccggtatt gtctacatcg atgggatgga atcttctaaa gagaggatgg acaatttgaa
     5341 tcccgatcgt attgcgtcta tgaatgtgta caaaggaaac gaggcgatcg ctaaattcgg
     5401 agagaaaggt cgtaatggcg ttatcgagat aaaattgaag aaatgatttt cgcgtatata
     5461 tgcaaggtag gcttgttcgg ctccctctgt gcgggaatgt ttctaacctc ctgtatggag
     5521 cgtgaaaacg aagaagcgag caagcgggtg attgaggtag gtaaagctat ctcatcgcct
     5581 gccgagctga aagcctctga ttattttgat gagatccggt atgtcccttt agagacgagg
     5641 gatgattgtc tagtcggaag ttctcctgat atcaagttat tggataaata tattctgatc
     5701 acttccgcta accggcaatg tcttttgttt gataaggcta caggaaagtt taaatgtcag
     5761 atagggcatg tagggaagga tccgggtggc tatagaaacg tagactgctt ggtggacgag
     5821 ttgaacgggc gtttgctgtt taatggatgg ggacatgatt tgattagcta taatctggat
     5881 ggcaattata tcggaaaaat agagcttctt atttttctaa gaaagtattc ttgaggttag
     5941 taaatagata atttggaaac agctttattc gatataacac ggccttgtca tgactgactt
     6001 gtgccgtgtt tttttattta tttacttgat cattgtaatg atattcttcc caagtatgat
     6061 cccaaggaag accgctatca aaccaaggat attactggca agtacattga gtagtgccat
     6121 cttgtattct ccggtacgca taagtaccat cgtgtcgaga gcaaaagaag agaaagtcgt
     6181 gaaaccaccg aaaagaccag tgaataggaa agctcttgta ttgatagaaa aattataggc
     6241 ttccgctata ctccagcaga agccgattaa aaaggagccg atcacattga ccgacaagat
     6301 accaaaagga aaggagtaaa gcatcgatcg ttgcacccac gtggaaactc cgaaccgtag
     6361 cgcagatccg atagctcctc ctattattaa aagaaaaacc tttatcatat caacctagtg
     6421 tgtttccccc gggctaggtt aaggcccggg gagatggtaa atgatttagg ttttcaattt
     6481 aattggccga ctcaaactgt ctcaagaaac gaacatcgtt ttccgagaac atgcgtaagt
     6541 cttttacttg gtatttcaaa ttggtaatac gctcgatacc cattcccaat gcgtagcctg
     6601 aataaacctt gctatcgata ccgcagttct caagcacgtt cgggtctacc ataccgcaac
     6661 cgaggatctc tacccaaccg gttcctttac agaaggggca acccttacct ccacaaatgt
     6721 tgcaggagat gtccatctcg gcggatggct ccgtgaacgg gaagtaagaa ggacgcaagc
     6781 gaatttttgt atccggactg aacatttcct tggcgaagaa caacaaggct tgtttcaagt
     6841 cggcgaatga gacgttctta tctacatata acgcttctac ttgatggaag aaacagtgag
     6901 cacgatagga gatagcctca ttacgatata cacgtcccgg acagatgata cggataggcg
     6961 gttcttgctt ttccattact cgggtctgta cggaagaagt atgtgtgcga agcaatacat
     7021 ccgggttatg ctggataaag aacgtatctt gcatatcgcg ggcaggatgg tcctcggcga
     7081 aattcaagga agagaagaca tgccagtcgt cctcgatttc cggtccctca gcgatgctga
     7141 atcctaaccg tccgaatata tcgcaaattt ctttctttac aagtgataga ggatgacgag
     7201 tgcctagttc gatcgggtaa gccgtacgag tcaaatcgat atcatcgttt gcggtctgta
     7261 cattctcaaa gctttctttt aattcgttga tcttgctctg ggttgtttcc tttagttcgt
     7321 tcaagtattt gccaacctca cgtttttgat cagccgctac attacggaaa tcattcatca
     7381 acgccgatat ctcgcctttt ttgctgagat actttatacg taaagcttct agttcctcgg
     7441 catttgccgc tttcatattc tctacttctt gaagcagagc cttaatttta tcgagcattt
     7501 ctaatcacac tttgtatttg tcatgcaaaa gtacgccttt cttttgaaac cgcaagggat
     7561 tcgtaaggtt ttttagttaa atgtaagcgc agacacttag gtgtcttgtt ttatatatta
     7621 aagtatttat atatcttcgc agcataatca aactataaat taattaatgg aaatagtcat
     7681 tattattggc cttatcttac tgaatggaat tcttgcgatg tcggaaatcg ccttggtctc
     7741 agcccggaag gctaggttgg aaaccgaagc gaaacgtggt aataaatctg cgggcactgc
     7801 tttgaagctg gcaaatgagc cggataagtt tctctcaacc atccagatcg gaattacctt
     7861 gatcggtatc ttgaccggtt tgtactctgg cgaggcgtta gctcataatt tcgctgttat
     7921 aatagcgcaa ataccggccc tagaaccgta tgcgttgggg atcgctaaaa cgacgatcgt
     7981 tattatcgtg acgtatctta cacttatatt cggagagttg gtaccgaagc ggatcggcat
     8041 ggggtgtgcc gagaaggtct ctatgttagt tgctaaaccc atgaattttc tttccttgat
     8101 atcctctcct tttgtttggc tactttcaaa gagtacggcg ttggctgtga agatgacggg
     8161 cgtggatacg aaagaggaaa atagggtaac agaggaagaa atcaaggcga tcgtgaaaga
     8221 gggcttcgac ggtggcgagg tgcaagaggt agagcaggac atcgtagagc gagtctttaa
     8281 tctgggagac cgtaacgtgg gttctatcat gacgcatcgt agcgagctgg tttggctgga
     8341 tgtgacggat agtacggaga agattcggga gaaagtggag gagaacttat ttaatatata
     8401 tcccgtggcc tcggagaagt tcgataatat agtaggggtc gtttatctga aagatttgtt
     8461 cggaaggatc gatcaaccgg atttctcgat caatcaagta cttcgcccgg cacagttcgt
     8521 tcccgagaac cagagcgtat ataacgcctt ggaatctttc aagcagacac acgtgaaata
     8581 tggactcgtt acggatgagt tcggaggtat ccaaggtatc gtaaccttga aggatattat
     8641 ggaaggctta atcggacaag taccggaagt cggagaggag tccgagatca tacaacgtga
     8701 ggatggtact tggttggtgg acggccaata ttctttctat gatttcttgg aatatttcga
     8761 catggaggat ttgtatgccg agcatgatta taataccttg agtggcttga tcctagagat
     8821 attggaacgt gtaccgaaga cgggtgagaa attaaagtgg ctggactttg agttcgagat
     8881 cgtagatatg gatggcgccc ggatcgataa ggttttggtt aagtacttga aaaatgggta
     8941 aaatgtcttt ttagaagagt acgccgagtg agatactcat cacgttcgtt cgcttgtcaa
     9001 tattgatatc ataattaatc tcgggaactg gattgttgac tttctcgaaa tcggattcca
     9061 cttgattcaa tccgaactca tagacaaagt cgaagaatag ccgtccgatg ctaaccccta
     9121 cgcccgtagc gatattgact ccgaacgggg tgttgtcatt cacgtattct acatgcgtgg
     9181 tggaagattc taccgtatag gcgatcttat agttgtattt taatttgggg ccgaccataa
     9241 ggctaagtcc gtaaggccct ttcttcacta ggttatagcc taccattatg ggaacctcta
     9301 aggaactggt tttcatcatc aagaggtcgg tagttgccga tgtattggac agcatattat
     9361 tttccggcaa actttgaggt atggaaaaac ggatatttcc ctcggagcga tgccatgaga
     9421 aactaggctg gaggaagaac cgttcgatat tgacccggca aaagaccgcg gccagataac
     9481 ctaccttata ttcgatgtct atattctccg cttccttccc attgatggaa agggagttta
     9541 tgactgggaa agtggcgttg aatcccactt tggctccaaa gttgaatgcc ttgtcctcga
     9601 aacgcatgaa gctctgggct tctgctaaca gaccgaaaga tagcaacgct cctataaggt
     9661 agactttttt cataccgtta ttttttcttt ttcacggacc agccgaattt accgacaaat
     9721 tcacctaacc cgtaatactt accatgcgag taagccaaaa gatccgcttt ctgcatatca
     9781 aaagcccctg tctctgggtc tagatatcgg tcgtcggcct gtacgtttac gacatcagcg
     9841 ataaacatat catgacttcc gagagcgatt acctctttta cccggcattc gatacaaagc
     9901 ggagactcgt ctatcgtagg ggcgttaacg acggtcgctt ttccgggagt gagcttcatc
     9961 tcctcgaatt tatgatggtc tttccctgag tttaccccgc accaatccgt ggcgtaggcc
    10021 agctcacgat tcgtcaagtt gatgacgaat tccatattct tcttcaagat cggataagag
    10081 aatcgttccg gacgtacgga tatatagcac atcgccggat tcgtacaaat cgtaccgacc
    10141 catgcgactg ttattatatt gtactcggaa ggctcattcc cacaactcac cattacggct
    10201 ggcaatggat agatcatggt tcccggtttc caatcgtgct tcatataaaa tgcagttttt
    10261 acaattgcga gttgagaatt gagaattagc tccacaaagg tctttgactt tcaattctca
    10321 attctcaact ttcaattatt taatgataat gtcttcttta ttaatcttac gttcgcaata
    10381 atgacattta atggttccct tctccttgtc gatcacgtgg aagcgggaaa gcatcggctc
    10441 attattggtg atacatttcg gattgttaca tttgaccaag ccaatcagct cgtcgggtaa
    10501 agtaaccgtc ttcttctcta caacctcata atcacggata atgttcaata taatattcgg
    10561 ggcgatcatg gcgatacggt tgatctcgtc ctcctcgaaa aatttgtcgg cgatcttgat
    10621 catacccttg catcccatct tgttgctatg gaaattattg ccgatcgtga tcgtattgtt
    10681 cattttctcc agtcccagta aagaggctac cttgaataat tggctgggag gaatatggtc
    10741 tatggcggta ccgttctcta aagcggctac ctgcaactct tttttctttt ctgctgacat
    10801 aaaacttcgt ttttattcgt cgatagatat acctaaaact tcgcaaatga tagcttggcg
    10861 tgcgaacagc ccgttgcgtg cctgctggat gtaataagcc tttggattgt catctacatc
    10921 gtaagcgatc tcgttcacac ggggtagcgg atgtaagata cgcaggttct cacggctgtt
    10981 tctcagcatg tcattacgca ggatatacac gttctttacc cgctcgtact cttccaagtc
    11041 tgtgaaacgc tcacgttgta cacgggtcat ataaaggata tccgtctggt tgatgatatc
    11101 ttccgtgaaa tcggtatgct cctcgtattt gagcccgtgc ttgtcgcaga agttcttttg
    11161 ctcgtccggc atgcgcagct cgttcggcgc gacgaagtgg aaggtcggat ggaagtgaga
    11221 cattcccacg atcaaggagt gaaccgtacg gccatacttc aaatcgccga ccatcgtgat
    11281 ggtgaggtta tccagtttgc cttgtgtctt gcggatggaa tacaggtcca gcatggtttg
    11341 cgagggatgt tggttcgccc cgtcaccagc gttgatgata gggacatccg tcacctcaga
    11401 agcatagcgg gcggctcctt ccagatgatg tctcataatg atcaagtcca cgtaattgct
    11461 taccatcaag atcgtatctt tcaaggtctc gcccttggag gaactagtcg tggaagcgtc
    11521 cgagaaaccg atcacccgtc cacctaaacg gtttacggct gtctcgaaac tcagtctcgt
    11581 acgtgtagag ggctcgaaga acagggtggc ggcgactttg ccttccagta atttccggtt
    11641 cggattttcc tcaaacttcc ttgcgttatc cagaatacga agaatgtcct ctttggaaca
    11701 ttgatcgata gaaactaaac ttttactttt cataggttgt gtatattctg tcttatgtac
    11761 gcgaatgtat aaaaaaagcg gagaccgaag ggcctccgct ttatatttta ttttaagaaa
    11821 tcaactagac ttgccggaag atagaatgtg ttatttttat cgacataaac gacgacagag
    11881 tttaaccgta tctcatcttg gcctttcttc ccggacttca cgatgttgga gaacggggtg
    11941 atcgttagct gttttttctt atctttcttg ttcttaacga tcaaggttgg agaacctttc
    12001 tcgtcggcgg cagggacgat ctcgcaagtg taatcctcga atacgtccgt gtggcgtgcg
    12061 aagttcttgc ttgtaagatc ttccaagttt ccgtgtgtca atccgaacaa attgcataag
    12121 tactcattca gctcgatgtt cgtattcata cctaggggta aggttccttg cggatggtaa
    12181 gcggctagga atacttcctc gcccgtatga ccgccggtcg tgaaaccgaa gcaagtgcgg
    12241 gaagtgatga tatgcgccat caatccggtt aacgagccac tgtacatgga ggaattatct
    12301 tccggtttgc gttggtcttc tggtatcggg ctgttcttgt agtccttgca attgttcaac
    12361 gcgttcatct cttccggagt cagctcgaag ccggcgtagg tgcggaatac gttttgcact
    12421 tctgagttag gaacgctgtt taccttgttg gcgaaaccct cggctgtcaa tttatacagg
    12481 gagaattggt ggaacaattg gtctttcgtc aatttatcgt aacctttaca atcttttcta
    12541 cctaagctga taccgctgtt tccgtggtcg ggtacgatga caacggcagt ctcgccatta
    12601 ttgcgtgcga actccaatgc ggcaccgcag gcacgatcga atgccaagaa atcggtagcc
    12661 atacctaccg ggtcatttcc atgagcggcc cagtctacct tactgccttc taccattaag
    12721 aagaagccat tcgggttctt ggataatttg tcgatcgcct tacgagtcat ttcctcgata
    12781 gaaggttgct cttccggatt gcggtcgata tcgtaagcca tttccttgtt gccatataaa
    12841 gcccacatct tctgattatt atcggcacgc atacctttca ggtcgtttct atatacgccg
    12901 tatccgttcg ccaatagata atcttccata tcctttgtaa ggatagaaac tccaccaccg
    12961 ataacgacat cgatatcatt atgaaccatc tgcggagcga tccagtcgta tttaccacgg
    13021 ttgtagctat gagcggagca gtccgccggg gtagcgtgcg ggaattcgca agtgaaaacc
    13081 aatcccgtgg ctttgccctg caacatcttt ccagcctcca atacggtggt aagcggttgg
    13141 aaggcacggg ccgggtcggt cgggtagata tcgttatcac cgtcgttctc cgggtaagtg
    13201 gatacataac ccgtacggct cggttgtccg gtcatgtagc atgatgtagt aggagcggag
    13261 tcgccgatag gggcgttaga agaatgcgta cgcaccgttc cgcacaaata cgggtcgatg
    13321 ttcaatttcg gtttgctggg atcttggtac cattgcaacc aacgggcgat agagatagtc
    13381 gccaatgagg ttccgtccgg gattaagaga atcacgttct tgacaggctt cacgttctcc
    13441 ttttccacgg cattggccgg catgatgata atagccagca aaagcagaaa agctaatgtt
    13501 tttttcatgt gctttaattt aataatgtat aacaaattct tctattaaat cctaatttcc
    13561 aagtgggatg atctcctcgt tgaaccgtgt caacttctcc acgcccgtct ccgttacaag
    13621 gaaactgttc tcgataccca cggcaccgac acccgggatc acgaatttgg gctccaaggc
    13681 gaacaccata ttcggtaaaa gctcctcttt cgagcgaggg gtaagcacag gtagctcatt
    13741 gatctgtata ccgatgccat gtcctacgaa tttagcctgt tgctcggttc ccataaagtt
    13801 agccgaaaga ccttctttct tagcgatatt cgccgctata ttatataaat ccgaacaagc
    13861 ggttcccggg cgggtagcgt tttccacctc ctgctgtatc gtaagggcca cttgatgcgc
    13921 ccgataagct tcctccgtca ggcggcctac ggagaagaca cgggtcatgt ccgtcatata
    13981 agccgtataa ttgccggcca tatccaccat gatagcggta ccttctttta ataaagtacc
    14041 gttagcgccc agcggacaag aagcgtctat gccgcctcca cccaaagcga aatcaaaagg
    14101 ggatggggtc tcggcgtttt ccccggcgag aatactgccc atatagatat ccatattggc
    14161 tccgaaagca cggaaaagac cgatcgagcc gttcttgcgc atacgtttct cgatctcgta
    14221 ctgaaactcc aagtctgtca taccgggacg gaaacattcc gggatctcgc tataagtagc
    14281 ctcatgcttg cgggcggcga tacggaattg cccgatctcc caaggggttt ttacccggcg
    14341 aaggtttcgc atgaaagcgg tggcgttacc ggcctcctcc ggttggaata ccttttgtaa
    14401 acggatatat tcattataag ttaactcatc tgcctctaat aagagtcttt tcggcatctt
    14461 aattcctcgt tccgcaaata aggttgggat gtcttccggc ttacggatgt attccacttg
    14521 atgtcctgaa agcccgttcg gtcgcttgat caggaaccac ggctcaccgt ctaccggcaa
    14581 ataaaaataa ccactataga tttgtcctgt cgtataataa agatttacat ctacggtaag
    14641 caaacaggca tccataccca tctttgccat accatctctc atccgatccc attttatctt
    14701 taggtcgttc ttcaattctt ctgaaatcat cttcctttgt attactttta ttttgtaccg
    14761 ggcatcaaag gtaacaagaa tttacgagat ttaagtggat ttgaggtgaa taaagtatta
    14821 caaacgcata tatgcgaata tacggttgaa tagggaaatc ttcttatgaa taaagataat
    14881 catatctgta tctattcctt gattctcgtc gtgaatccta taaaccacgg cgtggtcttt
    14941 acagatcatg gcgtggttta caaagaccac gccgtggttt gtagaataga agtagatccg
    15001 atatagaata tataagtatt cagctggtta ttcttgcgga acagataggg tattcgatac
    15061 tattggaccg ggatcttgat aaccaccttc cggatattcc cttggccgat acccggggcg
    15121 tgcccgtctt ccgggaaata aatggcgaat tgtccgggat agattttcgt ataggcggta
    15181 ggtttgtcga tataaaaggc gatatcttgc tcctcgttgt atggaacgga ctcctctagt
    15241 aattgatctc ccggtttcca cccgattttc tctacgccca ataaggggaa ttggatatcg
    15301 ataaatttct tgtgggtctc gatggccgct tccgacttct cctttccgaa gaggctggcg
    15361 atgctaaccg tgaaaccagc gtccgctata tcgtatttac catcttccat ttttgaaaaa
    15421 tcagtagact taacatagtc aaaagcctgc ttaaacagcg gatggataca ttcgatccgc
    15481 ttagagttct caagtgagtc tagaatcata ttgttattaa gttttagtaa ttggtttgaa
    15541 aatccttaca aatgtcgggt atttccctgt taaataatag tcatatttct caaataaatc
    15601 tattaagttc ctaggtttct taacgtacgt aaatactgtt tcgtaaagtt tgcaatctgg
    15661 ttgcaatcat atttatcgta tctttgttat tcatttatat ataactaaac aggtgatacg
    15721 atctatgaaa gatttggaga caattatatt accggttctc gagatgagtt gcgccgtatg
    15781 tgccaataac gtagagaata cggtgaaggg acttcccggc gtggaagagg catcggtgaa
    15841 tttcgcggcg aatacgcttt ccgtcaaata ccatccatcc ttgattactc ctcagaaaat
    15901 gagagaggcc gtgcaggagg ccggatacga tttggtcgtg gaggtagagg atccgacggc
    15961 ggtacaggaa gagatggcac gagagcatta ccggaagcta cgccggaata cgatcggggc
    16021 gtgggtactt tccattccgc tggccctgct gggaatggtg tttatgcata cgcccggcgg
    16081 taactggatc atgatggcgc tggccttggt gattatgatc gtgttcgggc ggtcgttcta
    16141 cgtgaacggc gtgcgccatg cgttgcacgg tagcgccaat atggatacat tggtggcgtt
    16201 gagtacctcg atcgctttcc tgttcagttt cttcaatacc gtatacccgc agttctggta
    16261 tgagaaagga ttggagccgc atgtttatta tgaggcatcc ggcgtgatca tagcgttcgt
    16321 cttgttgggt aaacttctgg aggagcgggc gaagaacagc acttcttccg ctatcaagag
    16381 cttgatggga ttgcagccta aaactgcccg tcgtgtgcga gatggtcagg aggaagaggt
    16441 ctctatctcg ttcttgcggg tgggagatct tgtcagtgtc cgtcccggtg agaagatccc
    16501 ggtggacggc acggtgtctc aaggttcctc ttccgtggat gagagcatgt tgagtggcga
    16561 gccgattcct gtcgtgaaat cacaaggcga ccgagtcttg gccgggacga tcaaccaaaa
    16621 gggcgctttc ttgatggagg cgaccggggt ggggagcgct accgtattat cgcaaatcgt
    16681 acagatggta caagccgccc aaggaagtaa ggcgcccgtg cagcgtatcg ttgataaaat
    16741 aagtggtata tttgtaccga tcgttgtcgg attggcgata cttactttta tcgtctggct
    16801 ggtagtagga ggaagcgggt acttctcgta cgctctctta tcggcggtat cggtattggt
    16861 gatcgcttgc ccttgtgcgt tgggacttgc tacgccaact gccttgatgg tcgggatggg
    16921 taaaggcgcc gagcatcata tattgatcaa agacgctttt gccttggaaa acctttgtaa
    16981 ggtggatacc gtcgtgctgg ataagaccgg gaccttgacc gagggcgtac ccgaggtgac
    17041 tgactctttc tgggtatcgg aggcaagccg ggatatgctg gatatccttt ataccgccga
    17101 gatgaagtct gagcatcctt tggcgtccgc tatcctctca tggttgaaag gaacggaggc
    17161 tgcggagatc gacgctgata gtttcgagag cgtaacgggg cgtggtatcc aaatgcaggt
    17221 acatggcgtg acgtattggg taggaagcaa aggctttttg gaaaccttca aggcgatggt
    17281 tccgcccgag gctgggcggg aaatcatccg gtgggaagag gatggcaaga gtatcgttta
    17341 ttacggttgg gaatcggaat tgcttgcggt catggctatt tcggatcggt tgagacctaa
    17401 gtcgggagag gcggtagagg ccttgaaaga aatgggtatc gaggttcatt tattgaccgg
    17461 cgatgggaaa cggaccgccg agaccgttgc ggccatgctg gatatccgtc attataaggc
    17521 ggatgtcttg ccgagcgata aggaggagta tatccgttcc ttgcaagccg ccggaaggaa
    17581 agtggctatg gttggggatg gtatcaacga ctcgcaagcc ttggcccgtg cggatgtgag
    17641 cattgcgatg ggtaagggaa cggatatcgc catggatgtg gcgatggtca cgttgattac
    17701 ttcggatttg atgttattgc cggatgcgat ccgcttgtcg aaacgtacgg ttcgctcgat
    17761 cctccagaat ttattctggg catttatcta taacttgatc ggaatcccat tggcggcggg
    17821 ggtcttattc ccggtgaacg gattgttact gaacccgatg ttggcgagtg ctgcgatggc
    17881 tttcagttcc gtgtcggtgg tattaaatag cttacggttg aaatggagta aactttaaat
    17941 aataagtaga gatatggcaa cattaaaatt taagacaaac gctaaatgtg gcggatgcgt
    18001 ggcggctatc ggcgctaaat tgaataaatt agtaaaagag gacgcatggt cgatcgactt
    18061 gaaatccccg gataaaacat tgactataac aaccgatctt ccggcggaga caattctttc
    18121 cgccgtatcg gaggccggtt tcaaggctag cgccttgtag tcgtagcgat cggatggatg
    18181 agaaaacaaa gacagactca tggtgaggaa gtagcgaatg tgcttacgca tggtgcgggc
    18241 atgttgttcg gcttaacggc gattgtcgtc ttgatgatcg ccgggattcg tacaggtgat
    18301 ccgtgggtga tcggtagttt cgccgtttat gcgttgtgca tgacttcctc gtatgtgacc
    18361 tctacctttt accacgccgc ttccgatccc aagcggaaat gccagttgcg ccgttgggat
    18421 catagcgcta tttatttgca tatcgcgggt acttatacgc catttacctt ggtggctctc
    18481 cgcgacgagg gtttctgggg ctggggatta tttattacgg tttggctggc agcggttatc
    18541 ggcgtatggt ttagcttccg tcggatgaag aaaaaggata atctgaaaac ggtttgttat
    18601 ctgctgatga gctgggtggt gattatcgct ttcaaaccat tgatcgatgt tttccagcgt
    18661 acggattcga tgtatgtctt atattggttg atcggaggag gcttgttcta ttccttagga
    18721 acgatttttt tctttctgga taaatataaa tatatgcatt ccgcatggca tttattcgtt
    18781 ctcgggggaa cggtttgcca ttttatagcg atctataatt tggtgtaagg aaaaataaag
    18841 aagccggaac tgtgtttagc ggttccggct tcttttattc ttgttcttcc ggatgttgtt
    18901 tcttgtattt ataatccgct aaaatcaacc ccattgaaaa gcaaggaagg gattcgccag
    18961 ctggaggata ggcgggggtc gtttccgact tccgctaggt tactccatag ggagagcata
    19021 ttacccgtgg cgttcatctc ggagatcggt tgggatagct tgcctctctc gatcaagaaa
    19081 ccttccacac catacgagaa atcgccggtc gtgctattgc agtttccacc gttgaagccg
    19141 gtcaccaata tacctttgtc gatagaggcg atcaatccgt ccagatcctt atcaccattc
    19201 cgcatggtaa gaatcgaggg agagccgatc gtttgttcca tgcccatctt gttggcggaa
    19261 tacgtatcga tataatacgt tttcaatata ccctgctcga ataccggaag acgtttcgtg
    19321 gcaacaccct cgctatcgaa ataacgtgcg ccggaagcct ttaccaaatg aggctcatct
    19381 atcaaggtca tcttgtcgct cgctaccttt tggtcgatct tatccaacaa gaaagagttc
    19441 ttttgctgga tggaggaacc ataaatggct ccgattactg gagaaagcag acgactggag
    19501 ttcatgttat ccacgatcat ggtatattta ccggacgcca ctttccgctg tcccagtttt
    19561 cgaagcaccc gttccagcgc tttcgtaccg ataccggtct tcaccagctc gtcataatac
    19621 aaggaagagt cgtaccaata agactcggga cgggcgtcac cctccccacg gatgctgaca
    19681 ctccccacca agccataaga ggaaccagaa gcctcgcctt cgaaaccgtt gctggctacc
    19741 atgtacttaa agtccttttc gtcgctgtag gaagcgttgg cggagatgat ccggtcgtcc
    19801 ttgcccatga tttcctcaca gacgctcatg gccaacgcta ccttgtcgtc cggttgcacg
    19861 gagtcgaaat tcgggtcgac caatcgcaag tccgccgccc cacctttata atacaaggaa
    19921 gcgtccggca gcgtgcgagc cttgtcctcg gcgaggaaac gagtggcgga gataccatcc
    19981 ttgatgaact tctccagctc tttcttatcc aagcgattgg tagagtagga gccgtaacgg
    20041 ccgtccacga acaaatgaac caccatgctg ttctcggacg cctgttgcag acggtctatt
    20101 ttcatatccc gtatctcaaa cgaactgctg gaaccattgt aaagcgtgac acgtgaagac
    20161 tgacaaccat tcttcaaggc atattccatg gcccattgag ccaatttctt attttcgttt
    20221 gttatcatat tagttttctc ctcctactgt aagtttgctg actaaggccg acggcatacc
    20281 gcaggttacc gggcaagact gtccatcctt accgcaggtc catgtgccgt tatccatttt
    20341 ataattatta cccaccatcg tgatatccgc caacgctttc gggccgttac cgatgatatt
    20401 gatatccttg ataggttggg tgagcttgcc gttctcgatc aagtaaccat ccttcacgaa
    20461 gaaggtaaaa tcgcctgcgc caatctgtac ctgcccgttc gtgaagttgg cggcatagat
    20521 acctttcttt acggtagaga tgatctcctc ttccgtcacg ttgcccgctt ccatataagt
    20581 ggcacgcata cgggggatag gcatctgacg gaaagactcc cggcggccat tgcccgtaga
    20641 ggggatgccg taatgttttg cgctgatacg atcgtgcaga taactggtca agactccctc
    20701 ccgtacgata taggtttttt gtccgtccac accctcgtca tcgatattga ccgagccccg
    20761 gttgaaagga atcgtgccgt cgtccaccac gttgatatgc tcgttgcaaa ctttcttgtt
    20821 cagctgatcg gagaaaatag aggtgttctt acggttgaaa tccgcctcga aagcatggcc
    20881 gatcgcctcg tgcaataaga tgccagagcc accggcaccc atgacaacag gcatttcccc
    20941 gccttttggc ttgatcgcct gaaataagat agaggtctta tccactgcct cttgggcaag
    21001 ctcgtcgatc aggtcgtccg tcaggaattc cgctcccata cgaaaagccc gtgcggcgta
    21061 cgagttctcg atcttcccgt tatcctccat gatgcagacg gcgctcaagg cgctcatcgg
    21121 gcgataatcg taataaatct gcccttccga gttacagaat aagatatgag aggtcgtgtc
    21181 tcccaaagag gccatcactt tggtgacccg cttgtccttt gcgaatatct gatcgttcag
    21241 tttctgcaag aaaggcatct tgtcattaat ggctatctcg tcccaaggtg tttgtacgct
    21301 atagaaattg ttcgtacacg ctttttccgt caggtttatt gcggtggtgt tcgccgatcc
    21361 ggtggcgatc cgtgcggccg tacgagccgc cttcagcatc tcgtctaagg taacgttctc
    21421 tacgtaggcg tatcccgttt ggtcaccagc caagactcgt acgcccatcc caaaatcgat
    21481 gttggatgag gcacggttta cggcaccatc ctgcaacccc acgttgttcc tgtatgaatg
    21541 ctcgaaaaac aaatcggcat aatccccgcc tttctccaag gctgccgcca ataccttcct
    21601 caaatccccc tcactcacct tgaaataatt catagcgaat gaaataccgg ctgctttatc
    21661 cccctcacta ccggtgcaac ttcctagtaa ggaaggagcc gctaatgttc caagcataac
    21721 catacctcct gttttaatga aatcacgtct gttaatattc atgttgttgt tgtttagccc
    21781 aatccatcac gtttgcgggt ggacgttgat tcaataattc ttttttcata aagtccatgt
    21841 aaggagctac atgcttgaag aatttcttgt atcccttaca tagataattt agtcccggct
    21901 ctccattcgg cgtatggaga aaccggtttt tcgggcactc tccatggcaa gcgaaaagat
    21961 attcgcattc cttgcattgc gtagggagct tatcttcttt atccgttcca aacttttgtt
    22021 gtaccggact gtacatcatc tccgttaatg tctttgtttg gatattcccg agtttgtatt
    22081 ctgggaatac gaaatggtcg caagcgtaca cgtcgccatt gaactccatt accccggcgt
    22141 gaccgcaatg gcgggccaag gagcagaccc cgggttgctc acctacccag ttggccaagg
    22201 tggaatcgaa taattggatg tagaacttgc cgatatcctc tttcagccac tcgtcgaaca
    22261 aggcgcaaag gaaatccccc catttctcgc tatctaccga gaacgaagct agctcgatcg
    22321 cagcgttttg ctcctcggga gaagatagct tggtaccttc cttgtgccgg ccgatacgct
    22381 ccacgatcgg ggcgaattgg atgaaacggc aatccagttc cttgaagaaa ttatagaatt
    22441 ccagcggata atccacgtta taatcattca cgacggccat ggcgttatac tctaccccat
    22501 gttttttcag caactcgatt cccttcatca ccttatagaa agaggggagt ccctgccggt
    22561 tcctacggta ttcgtcgtgg aactcttgcg ggccatcgat agatacaccc accaagaaat
    22621 tattttcctt gaaaaattgg caccactcat cattcaatag ggtaccattg gtttggatac
    22681 agttatctat ttgccgtcct cccgcatact tacgctgcaa ctccaaggct tttttataga
    22741 agctgatcgg ccgcatcagc gtctcgcctc catgccatgt aaacaagact tcttgcatgg
    22801 tttggcattc catgtattcc ttgatgaact tctcgagtat ctgatctgtc atgatgtgat
    22861 tctttacatc cggatagaac ttgcttttct caaggtaata acaatactcg catgccaaat
    22921 tacaaacaga accaatcggt ttcaacatga tgtagaccgg cttagcgaaa ggggaaatat
    22981 aggaactatt catggtatat tattagatgt tacatttcta tttcaactcg aactcgctaa
    23041 gtacaatttt ttgttttagt tcgctgaacg tttgatcgga cttagtcagt gtacggaagg
    23101 tatatttatc cccgtatgtg gaaagtacct tttccatctc attttctccg atcaagaaat
    23161 aacctttggc gggtgtttct ttatcgaagt catggaagat atttcccata tagaagttta
    23221 acccgtacag attccgataa atccgaaggt tatttacgac atatacattc tttttattca
    23281 atggatattc tttcaggata cgttcagcga aaacacggca agaatcccct tcacgaatac
    23341 ctctcataat gacaccatca attaataaat taaccgagaa tgtcaaggct atcgtagcgt
    23401 agagaatctt gatatttatt ttcttgaaca tctggtaata gaccgttcct aatatcaata
    23461 gatttatgaa gataatacag atcgtaagcg tgctgggatg aaccaatact tttgatacca
    23521 ttcgtaccat gtccaaggtc gatgcgtttt gtgtatattg accgacgata ccaacaggat
    23581 caataatacc gaataccgta agcaagatcg ctatcatgac gacacttact acggaagcta
    23641 aaaaggcagc gaatacccga gttactttcg tacggtattc tgtaatatat aaggcatact
    23701 gagccaagaa caaggcaatg aacggataag ccggcattaa atatacgctt cgtttactgg
    23761 aagggatcga atagaagaaa aggatgccga ttaaagcaac caaactaaat aaacgaactt
    23821 tttccatgga gcggatacgt ttccacgtat tctttaagat ctctttaata ggttgctcag
    23881 gcttgctaag tttcagcccg aataaagaga agaaaaagaa aatagtccaa ggtataaagc
    23941 ctgccgccaa cgtcatgaaa ttgtaccaaa caccattctc atgccccaga tcataggaaa
    24001 tttcaggagt gtttaggtgt aagaaacgag cgaaattctc cgctaatacg acattaagga
    24061 actcatctcc cccctgcttc catgcggcgg tataccacaa catcggtagg aataaagagg
    24121 aaattcccgc atataataaa gtcttgaata tggtgagata actgtattga cctaacatta
    24181 atagataaat gccgaatacg aataggggca atactacgcc taccggtcct ttggtcagaa
    24241 cggcgcatcc taataataaa ggtatgaata tgggaagtcc tttcagctct aatttatctt
    24301 cccatcgata tagctggaaa agccctatga cgatgaaagt agtgagcaac atatccaccc
    24361 gagtcgtcat ggccgcccga tgtatctcta cgcaggtgac caataggagg gtcgctatga
    24421 atgcctcctg aaactttacg attcgtttac cgaaaaagac caatacgaac ccgatcaagg
    24481 taataaaggc taaagccgat ggcaagcggg aggtgaactc ggaaacatat ccctgtggat
    24541 aggagaaagc agccattaac caatgcgcca tcggtggctt aaaagcgaac tcgttggcgt
    24601 aggattgtgg caagacccaa ttgcccgtct cgagcatgga gatcgctacg gccgcttccc
    24661 ggggttcccc tttggtggag aagtcgccga ggccgatcca aggtaacaca gatataatac
    24721 agattactac catcatggtt accggctttt gcaagtaaag atattgaagt gtaggtgtac
    24781 gcatatgaca attaatatat agggctttgg cccattaatg ttataaaaca gtttgcaaaa
    24841 gaacaatttt ttatggactt tccccgcatt tttagaaact ttttatgtgc ccaatgaatg
    24901 tttgatagcc tttcgtatcg cttccgcatc ctccttgttt tcctttaata tggagagaat
    24961 caggtttaaa taactctctt tgttactgat accgcagatc gcgcataggc ggctctgtgg
    25021 taacatccct ttttgattat aaacacggag gatgcttttg tagttctccg tttctatata
    25081 agactcgaac tcttctttta tgtttttgta tatttcttcc acatggatgt tcagacggat
    25141 actctctaca tgttcggtta attgctccac cgtcgttatc ttgcgatcaa cggtagtctc
    25201 cagtttttta cggacttgat gtttggcatg aaggattact tgcgagtcca gttctttttg
    25261 gaaaagacgt actacgtttt ctttcacttg cttgaaaaca tcgtccggat ctttcatcaa
    25321 ccgtttggcg accgtcttga tcacatcctc tatcatcaat aggttctcca cttccgctac
    25381 gtccggtaca taaatatgtt gttcccgtag atagtttatt tctccttgtg tacgcctatc
    25441 acgatctacg atacctttgc tatctaatgt atggaagtct ttcagttggc cgaacgcttt
    25501 ggttgtctcg attacttttt ggcaaccacc catcggtttc accaaataat cggggaatat
    25561 gaaggggtaa agcttactgt cgatactgtt cgtgtcggtc ccttcgataa acaagatcgg
    25621 tttccggctg ccaagtattt ccatatatac ttcttccggg aaactttcat tactctcgat
    25681 taactcgtaa tcccatacgg aatgatccgc gtcgtaagaa cgaatccaga tccgtttgct
    25741 gtcggagcgg gaggtggcga aatcaatgtc atgtgtgaga taaacaaacg tacagtccgg
    25801 acgtatcgcc tcaatctcgt cccaaagctg gttctttatg gagttgtgga gaagggtttc
    25861 cggctcttcg atcacgagca aggcgttcgg gcatgcgcat aatgcggccc caatcaagta
    25921 gaacaccagt ttctcgctat cgctcatgcg tccggcggtg taggaatttg aatcacgccc
    25981 cgtggataca agctcgataa atcccgactt tcgtatcaga cgattatgcg gaaacatctt
    26041 ttcccagatc gcttgtataa tatctatctt ggtgatcgga ggatctactt cgttattagt
    26101 cttgcaggct tccttgaaat tgactgccgc ctcgaactcc tcgctctgga gttgcaaaat
    26161 cagtttctcg tattcagaaa tacgtggcat gaacagtcgt tctttgatca tagactgtaa
    26221 acgtgcgaat tcattggagg ccgataattt agattcgtca tcgctgatga ataaggcatg
    26281 tataccggat attcttttcg cttgacccgc atatctctcc aataaatctc tgccaaaaga
    26341 gctttttccc gcaccgttcg ctccgatcac gactaatatc ttcgtgtcta gcatgatggg
    26401 atgtgtcaca ttaactttcg ttgggagtgt tagttccata catgttattg attaggtttt
    26461 caaagataag ctttttcttt gaaagttcgc acgagaccta aaaaataaag tgccttttcc
    26521 gaaacatcct taaagacggg aaaggcactt ttattaaaac cttagcagag ttttttctta
    26581 tttgctcttc tccaagataa cgcgagcgag gcgagcttgt atttgcatta atgtattaac
    26641 atcctcgttc tcgaaattga tgtcagctac ttttaaactt cttttggaaa ctaccggagc
    26701 cgatttagca gccattaatt cttgtactaa ttcatctact tgctctttga ttttctctgc
    26761 cttttttgaa taatctactg tacgtgccat agttcttttg atattttatt ttatgaatac
    26821 tatcgcaaag ataattacat ttttataata cacataataa aacgtaaata ttctgtgcta
    26881 tttttacgaa aaagtccgag ctgcaatatt ttcgcaaccc ggactaggta attatcgaga
    26941 tgaatgtgtg ttatgctttt gtcgtattcg tctcggatac gtcatttttt acttcccaat
    27001 ggaacggttc gaattcagtg ttcggatcta cccaagatgc tttcttagac gcatagataa
    27061 taaacggtgc cgcaacgaca acaattacac cgatgaagag aacggcgaac caaaccgtat
    27121 tatttcctgt agaaatctgg ctaggaggaa tgaaacttaa tacgaacgct aataaggaac
    27181 cacagaatcc taaacctccg atcaaccaca tcaagccatt gccacctttt ccgatacgga
    27241 aaggacgacc tgcctttttc atcttataac gtaatgcgat cgctccggag aacatcaaca
    27301 tatacattat taaatataag atcaccgtaa gctgtgataa gatctgataa aagctttgta
    27361 cggatggcat taccacgaat aataagctaa gaagtgtaac agccgctcct tggatataaa
    27421 ggatgttttt ctgtacgccg atcttattgg tcttctggaa gaacgggggc agataacctg
    27481 ctttaccaac tgcgaatata cctttggaag gaccagcgac ccatgtcaat actcctgcta
    27541 atacgccaaa tgccaaagcg atagcgataa ttggggataa ccatgaggca tgaatgtact
    27601 tgaagtaatt gtcgaatccc actaataaac tttgcgtaag attgatgtct ttctctggga
    27661 taataatacc caacgcaaaa gttcctagta cgaagattac aacggtgatc aaggcaccga
    27721 taaatacagc tttcggatag tttttagaag gattgtcaac gtctttcacg tgaataccgc
    27781 ccatttccat acctgcgtaa aaaaggaaga tacttgcggc taagactaag ttgtcgaatt
    27841 tactgaagtc ggggaagaag ttactgtgga aatccatatt ggaatgcccg ccagtcgcta
    27901 ggtatacgat acctaaaatg atgagtaacg ccgctggtat gatagtacct accatacctc
    27961 cgattttcgc tacttttcca acccaactca atccctttag tgagataaat gtagccagcc
    28021 aataaataat taacacgatc gctaatgtgt agtatttgtt attcgccagc agcatatctt
    28081 cgggatgatc cataccgatg aaggcgatgg atacggctcc aaaagttaat actgtcggat
    28141 accagatcgt actttcaatc cattgaaccc agatagccag aaagcctaga cgttttccat
    28201 aggcctcacc tacccaacgg aatacaccac cttgtttgtc ttggaacatt gccgctaatt
    28261 ccgctgccac caaagaggtc gggattaaga atacgattgc cgcgaataag taatagaaag
    28321 ccgaacttag tccgtatacg gcttctgctg gcagtccgcg taaagatact actgccgtca
    28381 cgttcatgat tgctagggta aacacaccta gctttactgt cttgttgata tttgccatag
    28441 atttatgttt taaaaatgag aattacttct ctcgtttaag tctgagttta taacagcgaa
    28501 tcaaagaaga tgttttgttt ttgctacgta aaacttggtt aattaacaca tttcgctgtt
    28561 taaacaaatg gtatatgagg tttgttgtca taaaccaaaa tgaaaaggat tataattaaa
    28621 taaatagtaa cgcttatgaa aatggccgta tttgatttcg cattgagaaa gaagggagta
    28681 tatggtgtgt tacatatcat tatactattg ttgtcgctgt tcttggttat cagtatctcc
    28741 atcgatacat ttaagaatat tcccttttac acgcaaactt cttataagaa gattcaatta
    28801 tggatctgtt tgttttttct tttcgatttt gttttggaat ttttcctgtc gaaagataaa
    28861 ttacgttatt tgcgaacgca ctttattttc ttgctcgtag cgatccctta ccaaaatata
    28921 atagaatatt atcatattat cacctcaccc gagcttagtt atttcttacg tttcgttcct
    28981 ttggtacggg gtgggtatgc gttggcgatc gtggtgggat ggttgtcgta caataaggcg
    29041 tcgggcttgt ttgtctctta cttgacgatg ttgctggcca cggtttattt ctcaagtctt
    29101 atattttttg tcttggagca caaggtgaac ccgttggtgg ctaattatgg ggacgctcta
    29161 tggtgggcgt ttatggatgt gacaacggtt ggctctaaca tatccgctat tacggttacg
    29221 gggcgagtcc tttcggtcgt attggctgct ttgggcatga tgatgtttcc aatatttacg
    29281 gtatatgtga caagccttgt ccaaaaaagt aacgaggaga aaaaaaggtt ttatgagaac
    29341 atgcaggctc cttctcccca gccagaggtg aaggataaat agaaactcta gttcctacag
    29401 tggatactgc gaggtcttcc cgtagggaac aaacaggctg gaggaagtgg cggagattac
    29461 actatgattt gctggaaagt ttgattggct tctgtttttt tcgtatcttt acggccccta
    29521 aaaccagata ggtaaaagat gataaaagat aagcaggcat tggaaggcgg gcgcatatcc
    29581 atacttggcg cacgtgttca taatctgaag aatatagatg tagagattcc gaggaataag
    29641 ttgacggtga ttaccggcat gagtggtagc ggcaagtcat cattggcgtt cgatacgatt
    29701 ttcgctgagg gacaaaggcg gtatgtggag acattctcgg cttacgcccg gaatttctta
    29761 gggaatatgg agagacccga tgtggataag ataacgggtc tgagtccggt tatctccatt
    29821 gagcaaaaga caaccaataa gaatcctcgt tccaccgtcg gtacgactac cgagatctat
    29881 gactttttcc gtttgcttta cgctagggcg ggagaggcct attcctattt gagcggggag
    29941 aagatggtga aatataccga ggatcaagtc ttacggctga tcttggatga gtacaacggg
    30001 aaaaaaacgt atctcttggc tccgttggtc cgtaatcgta aggggcacta taaggaactt
    30061 ttcgagcaga tacgtaaaaa aggatatctg aacgtccgtg tcgatggcga gttgaaagag
    30121 atcttccatg ggatgaagct ggatcgttat aagatgcaca gcatcgaggt ggtgatcgat
    30181 aagatgattg tctccgaggc agacgagcgt cgtttgaaag agagcttgaa gatcgccatg
    30241 aagcaaggcg atggccttgt gctgatactg gatgccgaga ctaacgaggt tcgccattat
    30301 agtcgtcgtt tgatggaccc ggtgaccgga ttgtcttaca gtgagccggc tccgcataat
    30361 ttctcgttca actcccctca aggagcgtgt ccgaaatgta aaggcttagg acaggtcaat
    30421 ttgttggata tggacaagat cgttcccgat ccatccttaa gtatatatag cggtggcatc
    30481 gtcgctttgg gtaaatataa gaattcgttg atattctggc agattgaggc gctttgccaa
    30541 aagcatggcg tgacgatcaa gacgcctata cgggatattc ccgaggaggc gatggacgag
    30601 atcatgaacg gtacggacga gcggttgcag atcaagaatg actcgttagg atcgtctaac
    30661 tattttttgt cgtatgaggg agtcgccaag tatatcttga tgcaacagga gagcgaggca
    30721 tccgcctcgg cgcagaaatg ggcgggacaa ttcatcaaga tggccacttg tccggaatgt
    30781 aacggctggc gattgaataa ggaggcgttg agctaccgga tagcgggaaa gaatatcgcc
    30841 gagttgtcgg ccatggatat ctcggaatta tacgagtggc tggagggtat cgaggagaag
    30901 ctggacccga aacagcttcg gatcgctacg gagatattga aggagatacg ctcccgcctg
    30961 cgcttcttgc tggatgtggg attggattat ctttccatga accggggttc cgctaccttg
    31021 tctggcggtg agagccagcg tatccgtttg gctacccaga tcggaagtca attggtgaac
    31081 gtactttata tattggatga gccgagtatc ggtttacacc aacgggacaa cgtccgtttg
    31141 attaattccc tgaaacaatt gcgtgatacg ggaaactccg tgatcgtcgt ggagcatgat
    31201 aaggatatga tgctgagtgc cgattacgtg gtggatatgg ggcctaaagc gggccgtctg
    31261 ggtggtgagg tcgtctttga gggaacgccc aaggagatgt tgcgtgtaga taccttgacc
    31321 tcttcctatc tgaatggaaa cacggagata gccgttcctg ccgagcgtcg gaaaggcaac
    31381 gggcagttta ttacgatcaa gggagccagt ggcaataacc tgaagcatgt ggacgtgtct
    31441 tttcccttgg gtacgcttat ttgcgtcacg ggtgtgtcgg gtagcggaaa gtctaccttg
    31501 ataaatcgca cgctgcaacc gatcttgagc cagcatttct atcactcgct ggaagacccc
    31561 ttggcatacg acgtcatcga gggaatcgag catgtagata agatcgtgaa tgtggatcaa
    31621 tctccgatcg gtcgttcccc ccggagcaac ccggctacct atacgggggt attctcggat
    31681 atccggaatc tgttcgtgga acttccggaa tcgaaggtga gagggtataa accgggacgt
    31741 ttctctttta acgtatcggg cggacggtgc gagacctgta agggaaatgg ttataagacg
    31801 atcgagatga atttcctacc ggacgtgctg gtgccttgcg aggattgtca cggcaagcga
    31861 tataaccggg aaaccctaga ggttcgtttt cgtgggaaat caattgcgga tatcttggat
    31921 atgacgatta atatggcagt ggagttcttc gagaatatcc cgacgatctt atccaagatc
    31981 aaggtcctgc aagatgtagg tctgggatat atcaagttgg ggcaaccctc tactacctta
    32041 tccggtggcg agagccaacg tgtcaagctg gctaccgagc tggcaaagcg ggatacggga
    32101 aagacgcttt atgtattgga tgaacctacc accggtctgc acttcgagga tatccgggtc
    32161 ttgctggggg tattgaacaa gttggtggat aaaggcaaca cgatcatcgt tatcgaacat
    32221 aacctcgatg ttatcaagag cgccgattac ttgatcgata tgggtcccga gggcggtcgt
    32281 cgtggaggca atgtcctttt taccggaact ccggaagctt tagcaaagag tggtgtcggg
    32341 tttacggctc cgttcttgaa agaagagtta gatatagcaa ataagaaaaa atgaagaatc
    32401 ctatacaaat gatcaagcag tgcgtggaga aggaggaacc ttacttcgtg ctgagagggc
    32461 aggacgtatg tgcgttggct gccatagaga cctattatga ggaggtgagg aataaggtga
    32521 aagatcctta tttcatcgag gagatcgaag agatcatgaa agatttccgg gcgtaccggg
    32581 aggaagtgtc taacactaaa ataccggatt gatttatggc agacgacagt tacaagacca
    32641 tcaagcaagt agccgaggga tattataccg agaagcgcag ccgctttatc tcgtatgcta
    32701 tccccgtgcg tacggtagaa gaggtgaagg agcaactgga gaaataccgt aaacaatatt
    32761 atgatgcccg ccatgtatgc tgggcgtata tgttaggtcc agagcggcag acgttccggg
    32821 ccaacgatga cggggagcct tcttccacgg ccgggaaacc gatcctcgga cagatcaact
    32881 cgaatgagct gaccgattta ttgattgtcg tagtacgtta ctttggtgga atcgagttag
    32941 gaaccagcgg gctgatcgtc gcttatcgca cggccgccgc cgaggctatc gccgccgcag
    33001 agatcgagga acgtacggta gacgaggaca tcacggtcgt tttcgaatac ccatacctga
    33061 acgggatcat gcgtatcgta aaagaggata accccgctat catctcacag aagttcgaga
    33121 tggattgcga gatgacgctt cgtatccgta aaggggaggc cgaacgcctc aagaatcgct
    33181 tgttaaaggt tgagaccgct tatctaaaag agtagcaagc gatcaactaa ttcaattttc
    33241 aattgttttt tgtagagaca aggctcatga ggaaccctgc ccctgcattt tattgtgtaa
    33301 atattaatat agttttatct gaatgaaaaa agttctttta ttctcttttt ttctagtgtt
    33361 gggtttggtc gtgtcgcaaa tgcttcccgc tatggtgggg gaacagtatt cgctggtaaa
    33421 gacgatctct aatacatttt tgtttatttg ccttgcgttt atcatgatta atgtggggcg
    33481 tgagttcgag attgataaga cccggtggaa gtcttatacc gaagattatt tcatagcgat
    33541 ggctacggct gcgtttccgt ggatattcgt ggctttatat tatatgtttg tcttgcttcc
    33601 gggcgattta tggggaagtt gggacgcttg gaaggagaac ctgttgctaa gccggttcgc
    33661 cgcgcctacc tcggcgggta tcttgtttac gatgttggcc gccgccgggc taaaagcctc
    33721 ttgggtgtat aagaaggtac aggtattggc gatcttcgac gacttggata cgatcctgtt
    33781 gatgatcccg ttgcaaatca tgatgatcgg cttgcgctgg caattgggag tcattattct
    33841 ggttgtggta ttgctcttga ttctgggttg gaagaaaatg ggatattata atgtacgtca
    33901 agactggaaa gccatcttgt tctatgctgt cgtgacgttt ggtatcacgc aagtgattta
    33961 tctggtatcg aaacatatgt acggggagga ggctagcatc catatcgagg tacttttacc
    34021 tgcgtttgtc gtaggtatga tcatgcggca taagcatatc gataccaaga tcgagcatca
    34081 agtgtccgat tttatctctt atctctttat gttccttgtc ggagtgagca tgccggtgtt
    34141 tatgggcgtg gatttcgctc agcaagcggc ggaagtaact acggtgacag gttcccagcc
    34201 gatgatgtca tggtcaatga tcgctttaca cgtcgtaatc gtctcattct tatccaatat
    34261 cggtaaacta tttcctttgt ttttctaccg tgaccggatg aaacgggagc gtttggcgct
    34321 gtctatcggt atgtttaccc gtggagaggt aggagccggc gttattttca tagccttggg
    34381 atatggatta ggtggcccta tgttgataat ttctgtgtta actattgtgt ttaatttaat
    34441 tttaactggt atctttgtca tctgggtaga gaaactcaca cgcagcgctt ataacctgga
    34501 gcaagcagga aaagccaaag ctgtcaatta atagaaaaaa cacttgaagg tatttcaaga
    34561 tgatatcccg tttccctctt gggagggaaa gggaatagtc atagtacgat caattgttga
    34621 agaccttcat ctaacttatt atttatggac cgtacgatta atgttatcct taaaccgttg
    34681 cgtcgcttcg ctatacagaa gccgaacgct agtcttttat tgtttgccgc taccatcgtt
    34741 gctatggtct tggccaattc gccttgggca gataggtatc accagttatt agcttttcca
    34801 atcgatctgc aagccgggca gtttaacttc tttgcgcatc atggcgagac tatgtctatg
    34861 ctggctttcg tgaacgacgc ccttatggcg gttttctttt tcgtgatcgg tctggagatc
    34921 aagcaagagg tattgatcgg tgagttgagt tccgtgcgga aggcgctatt gcctattatc
    34981 gccgcctgtg gtggaatgat cgtgccggtc ttattttata tgttagtatg taatacgcct
    35041 cccgaggtaa acggggcggc tattccaatg gctacggata tcgctttcgc cttggccgta
    35101 ttgggcttgt tggggaagcg ggtgccgttg agcatgcgta tcttcttgac cgccttggct
    35161 gtggtggatg atattggagg tatcataatt atcgccctgt tttatagcgg gcatatcgct
    35221 ttcgagcctt tgttgatatc cctgatagtc ctcgctttgt tgtatgtggg aggaaagttc
    35281 cgggtacaca accgattgtt tttctatatc ggtggcttta tcgtttggtt gctatttctg
    35341 gagtcaggaa tccatccgac aatcgccggc gtgttgatcg cctttacggt tccagcccgt
    35401 ccggttgtta agctagatga tttcacgtgt gatatgaccg ggtatttgaa tatgctggac
    35461 tataccgagg ttcgtcagtc ccgtaaagcg gaagtgctta cgcctacaca aattcaggta
    35521 ttgaataaca tccatacgtt ggcggataaa acgatcagtc cgttgcagac catcgctgat
    35581 aagttgcatc ctttggtaaa ctatgtgata cttcctttat tcgctttcgt gaatgccggt
    35641 gtgacattcg gggatatcca accccagaca ttggttaatg ttcccttggc ggtgttcgtg
    35701 ggcctatttg taggaaagac attaggtata ttctctttct cttacttgtt tgcgtgtacg
    35761 ccattcgcct ccatgcctac aggcatgagc aagcgtaatt tatttggagt atccatgttg
    35821 ggaggaatag gtttcacggt agccttgttc atagcgaatc tttcctttga cggcagtacg
    35881 gcggcgggtg ccgatctctt gaatcaggcg aagctgggtg tattcacggg atcgtttata
    35941 tccggtcttt gcggttatct ggtattgaaa tgggttttac ctaaagaaaa agtggaaacg
    36001 atctaaataa aaaggcagtc cggcaaggac tgccttttac attatattat gccgtaacta
    36061 aagtttcgtg agatcttgtt gccatgtaat atatgatttg ataattgagc acgccttctt
    36121 aaacctcttt ggatttgttg aatagcgagc cgatccataa taacaaaata gctccgaccg
    36181 tagaggttat caagctccct aagataccac cggccgatat gcctagtaaa ctgaataccc
    36241 agccacccaa tacacctcca ataataccta ggatcaaatt aacaatgacc ccgaaacctc
    36301 ctccacgcat aatcttacca gccagataac cggctacgat accgatgata atagaccaaa
    36361 taaatcccat aacgaatagt tttatatttt attaaaaagt tctgatgctt tgtatttaaa
    36421 cacatccgaa aagtctttgg ttgcgttttg tacctctttt taacgaatca ttccaaaaga
    36481 tctagcgaat ctatgaagga ttcatagacg ggatggttca attgaaagac aatcgcttcg
    36541 aaaggacgga gcgtgatatc tttttgaggc gccatatgac ttcggtcccc gtaattgtcc
    36601 aataggacgt gtgcgttact catatctatc cccggagtgg agattgccgc cttgggggag
    36661 aaattgagca taatcagata agtgtcggcc ccagtcttgc gtaagaaggt ataggattgg
    36721 ggattctccg catccagcaa atgataactg ccataaatca aactcggatt ctccttacgg
    36781 aagctgacta ctttcttaaa ataattaagt atggaggtcg gatctttttc ttcgtccgct
    36841 acgtttatcc aagtataatc cggatttacc tttaaccaag gggttcctgc cgtaaatccc
    36901 gcttccggcg agcgatccca ttggaaagga gtgcgggcgt tgtctcgtcc ggtctctttc
    36961 tgttcgtcca ataccgcctg cggatcttta ccctctgctt tcgctttctt atagcggttg
    37021 atcgtatcga tatcgttata atcctcgata tggtcgaacc gaatgttacg catacctatc
    37081 tcgtccccgg cgaaccaata aggcgttcct ctcatcgtaa gcagaaaagt aataagcatc
    37141 ttggcggaca aggccctgaa ctcatcctta tcgctaccaa agcgactgac catacggggc
    37201 tggtcatgat tacccaagta gatcgagggc caacccttat ctaccgcctt atcccattcc
    37261 gtaaacatct tctttagggc gatcaagcta tagtctatac cggattccgg attgtccggt
    37321 agggttgtat tccggatacg ggcggcgtcg aaatgataaa gcatattcaa ctcttcccgg
    37381 gccggatcga caaatttagc gacatcatct accatcacgg ccgaaccttc tccaacactc
    37441 atacaatcgt atttgcttaa tacctgccga ttcatctcgt gaagatagag gtgtaggcga
    37501 ggctctttgg catagaaaga aaagatatcc ggatatttct tggaatctat gagagggaat
    37561 gagggatctt tggcgataag agagatggaa tccatgcgaa aaccgtctat ccctttatcg
    37621 aaccagaagc gcatcatatc gaaaatctct tggcgtacct ctgggttctc ccaatttaag
    37681 tcgggttgtt tccgggagaa ataatgcagg taatacgagt cggttggctt gttatacgtc
    37741 caagcgttgc cttcctcgtc gaaatagctg aggcgcaagg gaggctcacc tttctcggcc
    37801 ggccaccaat ggtaataatt ataataggga ttatgtctgg atttacgggc ttcctcgaac
    37861 caaggatgct cgtcgctggt atggtttact accaagtcca gtaccagtcg catctcccga
    37921 cgcagcatat ttacatcact gattatcagt gactgttcat tttaatcggt acaacctctg
    37981 ttttgacaaa tacacagaat gtggggacaa atgcaaatcg gtgtatttca tagctttgca
    38041 tatatgtgtt gtaccacttt cttttagcct tttttgcgaa tgtccgctat cagatacaag
    38101 gtgttgaatg atagggcatt tccgcaggta tgttacagaa cacttgttga atacaaaggt
    38161 agtggttttc ttggaatttc tgtggtttgc ggtgtgtttt ttattttcca gaaggtgttg
    38221 gatgatagaa tcggtcataa aacctgaaaa cttttgtaag gtttacgttt gattcgcttg
    38281 aaaaagtgta gagcaatgtg caatgggtga tatacgttgg gaaaagtgta ataaggttga
    38341 attattcgca taaaaaatgt atgcgcgtat tacatacctc taaaagatac aaacaaatta
    38401 tacccatact ggtatattgt tgatgttttg tcttaatttt gtatccgaaa gggtataaca
    38461 ttaaaggtat tatgctatgg atatattaag tctcaccaaa gtaacatcat tgttcatcct
    38521 aactttaata gaaagagacg atggacaaaa gaaataaatt gtggagacgc caacaaatgg
    38581 ctcgtgtgtt taagactcgt atgattctgt atgccgctta tggtcattgc atcattcgtg
    38641 aggatggaag ctattatgaa catcctcatt ggtttgagtt ggcaaaagac aaatgggcac
    38701 aagtttacaa aactacagga actccgtgta gttgctggat gtgcagagga tttgaatatg
    38761 accgcaaaga gtataagaaa gaaactttgc gtattattcg ggaatcaatg gagtagttta
    38821 aagggacagg ataggaacta aatctgtgcc attatgcgca caggttcagt tccttacttt
    38881 tttgtgtagg gcaaggcttt atcaaagatt aaaaacacta ccgatattca gaataaatat
    38941 cttgtaatgt atcataaaat ccccaaccac aatccgatac gctatcaata agcttttcaa
    39001 tccgttcgta ataacaggct aacaatccgt tgagaaagat aaagcgcata gctttgtcga
    39061 aatttccctc cagtgttgta tagaactgtt cccacatatc gccaaattca agtgtgtatt
    39121 cgcatccttg ttcgatatag aacaacatta aatcggcaac agtggtcggc tccggtttta
    39181 gcttttgaaa atcggaaatg acttttcgac atttggcaaa tgacggcttt tcggaaaatc
    39241 cacgagttgg gaagaactcg tttctgatag ctttcttgct cttttctaat tcagcgttgc
    39301 aatctggggc aagataaaac tccagataat cttttgcctc tttacgtgca tcgtatagtt
    39361 caagaacaat gtcggttatc tgttcttttg taagtgacaa caagtgtttt tttagctttg
    39421 cttttgacat agattgattt tcaattgatt gtgtatttta cattcctgct aatttccaaa
    39481 caatcctttt tcttccatat atgcttccaa ttgatatgtt attaatccag ctgttttcta
    39541 taaactgaat ccaatgtgtt tccatctttg tctttccata tcaaccagcc attattactg
    39601 ctaccaatac agaaatctgc ggcagtactg ggacttgaaa aagttttatc tgatgtcaat
    39661 accaatattc cgttctcagt agaagtgtaa tcttgaagca ttttttctcg tttttctttc
    39721 cagttgaaag acggaaccat tgttttggca acagtacttc cttttaggac tgtaaagcca
    39781 tcggaactat agaagccctt tgcattgcat cctctacctt tggtgtagaa tagatgttct
    39841 tctttgggtt gtgatacatc aaaaatattg caaccgataa atgatgccag aaacttcaca
    39901 tcttcgaaaa attcatccat tgagtcctgt tgatgctctg gtagattcgg tgctttaggg
    39961 atttgtttat tatcgcttaa aacaaaagcg tttgctttct tggcttcggc tatcgcttta
    40021 tgttctaggt attgcacatc aactttagtc atatcggcat ctttcgatac gaatatgagt
    40081 gctttttgcc aaaacgcttt tttgctgtcg tggtctttta cacgttcttt gaaattttcc
    40141 gtttcaccta tatatgcctg cggttttgtt gattcatctt cccccagtaa tatatagaat
    40201 gcaggttttt gtaatttctc ttgtgtattc aaataggaga gattagaacg tggtacgaca
    40261 aacatttggc aaattttgtt gctaatgaat gcatattgag ttcctttagg atctccgtcg
    40321 attaaatatg ttgttacagt ctttcccatt gttattcaac ttcagtgatt ttgaggatag
    40381 ttgtacttac tgttatattc gtaatcgaag attttgcata aatatgtcta atttcaactg
    40441 ttttgaggta taacttattt aagtatagcc ttttcttaat gcaaatatac accattatcg
    40501 aatataattc gctatatttg cactataaaa tcgcattaaa caatgaagct aaataaaata
    40561 aagactgttt tgtcggataa aggcatctcc cagacatggt tagccaagca acttgataaa
    40621 agttttagca tggtcaatgc ttatgcgtgc aatagaattc agccgaattt ggaaacactt
    40681 cagcggattg ctgagatttt acaggtggat ttaaaggatt tgataacaga taaagaggaa
    40741 aggtaaaatg caatgaaaaa ctttacggag aatacaagag tacaagtccc ggctgcattg
    40801 catctttgca agctcggtta tacatatttg gatgatttaa catcatacaa tccccaaacg
    40861 aatattttga cggatatttt tatccgttca gtaaaacgtc tgaatcctgc tttgacggac
    40921 ttggaatgca gccagttact ggataaaatt gtcggaatct tgaataatga tgatttgggc
    40981 aaggaattct atactatgct ttcttccaac agtggtgtga agttgataga tttcgctgat
    41041 gcgaataata atgaatggca cgttacgaca gagtttacat gcgaaaatgt cgaatccggt
    41101 gatagcttcc gtccggatat tacgtgcttt ataaacggct tgcctttagc ttttatcgaa
    41161 gtcaagaagc ctaataatca cgatggaatt ttagcagagc gggataggat taataaacgg
    41221 atgcggagca agagttttcg tcgctttatc aatcttaccc aattgatgat tttttccaat
    41281 aatcaggaat acgataatga aaacagagtt ccgatacaag gtgcatttta ttgttgtgca
    41341 gcaaaagaga gagctttctt taatgtgttt agagaggctg atgctacttt cgtgtcgaaa
    41401 tatccatatt tagcgttgac ggaagattca gaaaaacagg ttctcaaaca taggaactgt
    41461 atcgttatta aaaacttgcc cgattatgaa accaataaga aggtagatac tccaacgaat
    41521 cgtgttttga catcaatgct ttgccgggag aggtttttgt ttctgttaag atatggcttt
    41581 gcgtatgtta atcgaactat agagctggaa gatggcagta aaatcacaac tcttgaaaaa
    41641 catgtgatgc gctatcagca attgtttgca tcattggcta ttcgcaaaaa actatctaaa
    41701 ggtgtcaaga gtggaataat atggcataca caaggcagtg gcaagacagc attggcgtat
    41761 tattcagttc gtagtttgac cgattattat gcaaaacgcg agacggctgt taaattctac
    41821 tttatagtgg accgtattgc gctgatggag caggcgagtg atgagtttgt tgcacgtggc
    41881 ttagtcgtaa ggaatgtcaa tagtcgggat gatttaatga aagatatccg cgataccacc
    41941 cctgtagtga acagtgaggg taaagcggaa ataatggttg taaacataca gaaatttaag
    42001 gaggattcca ctaaaataca gatagagtca ggctataata ctaatcttca gcgtgtattc
    42061 tttatagacg aagcacacag aggatatagt ccacagggta gttttcttgc aaatcttctg
    42121 gaagctgata aggatgctgt aaaaatcgca ttgacaggaa ctcctttgtt gcgagaagaa
    42181 aaagaatctt ggcgtgtctt tggtgattac attgacacct actattatga taagtcgata
    42241 gcggatggtt atacgctaaa actgatgcgt gaaccgatag aaaccattta taaagagcgt
    42301 attgagagca ttcttgataa attggctgga aacgtagagg tcaagaaaag tgatatagac
    42361 aaaaataaaa taattgagca tgaaagttac ctgaatgctt tgcttgatta tatcatttct
    42421 gatttgcgaa gattcagaaa agaacaagct gatgattcta tcggggcaat gatcgtgtgc
    42481 aaaacaaatc cacaggctcg tgaaatgttt cgtttatggc agcagcgttt tagatttgcg
    42541 cagcgcattg aagataaatg ggaagaacag ttgggaatgg tagcagagcc aatggttgcg
    42601 tatggtcatg ccaaaccatt acgtgcctct ctgatattgc atgatgaagg agacaaatta
    42661 gaaagaaagg catatattga agaatataag aagcagcaga cagtagatgt actgattgtc
    42721 aatcaaatgt tgcttaccgg atttgatgct cccaggttga agaaactata tttgggacgt
    42781 agtcttgacg gtcatgattt gttacaggct cttacgcgtg taaatcgtcc gtataaagat
    42841 tttaaatatg gctatgtggt tgactttgta gatataaagg aaaactttga ttctacaaat
    42901 gaccgctatc tgagagaatt aaaccgtaca gcggatatta aggagatcca acaggacgag
    42961 cctgttggta atgctattat cgaagataag gaagagataa tagcgaaaat gaaagaaatc
    43021 aagagtattc tctttaattt cacttgcgat aatccggaag agttcagaca ggaaattgat
    43081 gaaattgagg ataaagacag gctctatgaa ctacggtcag tattgaatga tgctaaagct
    43141 attttgaatc aagtcagagc ctttggtgat gatgaattga aagaaaaaat agagtctttg
    43201 gcttttggtg gtattcctac tttggttaca gaggttacgc atcgcataga gaggatgaat
    43261 ctgtttgaaa gtacagagca taaagcagat gttgccggaa taatcaatgt cgctctgtca
    43321 gaattggaat ttgagttcaa aaagggaata tctgaggaac tgagaattgt tgtcaatgat
    43381 attcgtgagc gttgcgaaaa ggtacaaact gaatttgatg ccaattttga taggaatgaa
    43441 gaaaaatatg tcatccttgc agatgagttc cgagcatatt tccgtaaaaa aggttttgtt
    43501 ccgcaaaata ctcaagatgc aaaagacagc attgattaca tggataatgt aatgaaaaag
    43561 attcgggaaa taaacagacg gaataatatc ttgaagaaaa aatataaggg tgatgagcgt
    43621 tttgttcgta ttcacaagcg gattgaggag gaaaatcaaa aacgtgaaca gcctattata
    43681 tctgcacacg aatatgaaat agccgagaat ctgtcacaga tgaagtctca aatagacaat
    43741 atgttattct tgaatatcaa tgttttggat aatgaagatg cctttaagcg tgatgtattg
    43801 gctattattg gtcgtaaatt aatagacctt ggaattaagg caaatttgac agaccgtaaa
    43861 tatatcaaca atcttatcac aacagaatat ttccaacaac gtaattttgc atattgatta
    43921 tgagcgatat aaatataaca gaatcaacga ttgccctgat tgattctttg aaaagtacaa
    43981 caggtgcatt tggtttggca ggaacaggaa gcgaatataa aattgtcaca gaaatgtttc
    44041 tgtacaagtt ctttaatgat aagttcggct atgaagccaa gcgagataaa atgtacggag
    44101 aacggctaag caaagcagaa aagtgggatg ccgaatatga tacatttaca gaggaagagg
    44161 tagaagacct tttcagttat ttgcctgctt ctgtgccgag acttaaacct gaacatacac
    44221 tctctcatct atataatttc acaggaaagg gagatttctc tacattgttg gatgctacat
    44281 taatagatat agccaatatc aatgcagata ccttttctgt aacaacttcc ggaaaaagta
    44341 aggtaaatat cttcagtgcc ataacaacat ttgtaactga ccaacaaaag cgtgatgaat
    44401 ttgcaaaatc gctgatgcgt aatgttgctt cattcaattt tgaacatgta tttattgaga
    44461 agtatgactt cttttcaaga atattcgagc atttgctgaa gggatttaat aatgccggag
    44521 gtggtaaata tgccgaatat tatactccac gtgccatagc ccaagttatg gcgagattat
    44581 tggtcgggga caatgcagat ttacgaggcg tgacttgtta cgacccatcg gctggaacag
    44641 gtacattgct tatggctctt gctcatcaga taggagaaga tagatgctcg atttatagtc
    44701 aggatatatc agaaaagtcg agtgaaatgt tgcgtctaaa ccttattctg aatagtttgt
    44761 ctgcttctct gccaaatgtt gtacagggca atacattgac agaaccatca catacagaat
    44821 taagtggcgc attgaagaaa tttgatttta tcgtttcaaa tcctccattt aaacttgatt
    44881 ttccagagta tcgtgataca ttagctgctg atacgattcg gttttgggct ggagttccga
    44941 ataaggttaa aaaaatcaat cccgaaaagc ctcagatggg aatatatttg tgtttcttac
    45001 agcatgtaat aaactcttta aaggatacag ggaagtcagc tgtcgtagtc ccaactggtt
    45061 ttattacatc aaaaaaacgt aacaatgttg ttgcctataa tattcttcaa aaaattgtag
    45121 atgaacatat agtatgtgga tgtatatcaa tgcctactaa tgtatttgct actaccggaa
    45181 cgaatgtgtc cgttatattc tttgataagt cggcaacagc agataaagta attttgattg
    45241 atgcaagcaa attaggtgaa gaatataaag aaggcaataa ccagaaacga cgtttgcttg
    45301 ataatgagat agatttaata gtcaatacgt tccgcaacaa agaagttgta gaggattttt
    45361 ccgtagctgt ttcttacgat gagataaagg aaaagggcta ttctctttct gctggacaat
    45421 atttcgacat caagatagat tatgtagata taacggaaga agagtttaac aaccgtatgg
    45481 caaattataa acaaatactc tccgagcaat ttaaagaaag ccatcggttg gaagaggaaa
    45541 ttatgaagca gttggatgct ttgcagttca acgaaaatgt aggaaacaat gagtaacgaa
    45601 atacagtttt tgttatacaa tcttcccgat aaagagggaa gagtacaggt ggttataaaa
    45661 gacgaaacca tttggtgtac gcaaaaggct atggcagagc ttttcggtat tgataaatca
    45721 ggtattagcc gccacatagc caatatattt agagaggaag aattacagca agacacgacg
    45781 gttgcaaaaa ttgcaaccgt cgtaaatcga ggcataagag gcgaggttga agagttggtt
    45841 gatttctata atcttgatat gattattgct gttggctatc gtgtatcttc tccaaaagct
    45901 accaagttcc gtcagtgggc taccaagatt ctgaatgagt atatcaagaa aggctttgtg
    45961 cttgacgatg aacgcttaaa acagggaacg gcagtattcg gaaaagacta tttccgtgaa
    46021 ttgttggaaa gggtacgttc catccgtgcc agtgaacggc gtatttggca acagattacc
    46081 gatatatatg cagagtgcag tattgactat gacaagaact cgcctaccac acacgatttc
    46141 tatgccatga tacagaaccg ttttcactat gccattaccg ggcaaacagc agcagaaatc
    46201 atctacacta aggctgacca tacccaagaa cacatggggc tgactacatg gaagaatgct
    46261 cccgatgggc gtatcttgaa atcggatgtg tcaatagcca agaactattt gcaggaaaat
    46321 gaaatccgtc ggttggaacg tgtagtaaca ggatatttcg actatataga agaccttata
    46381 gagcgtgaaa acacgttcaa tatggagcaa tttgcagcca gtgtcaatga gtttctgact
    46441 ttccgcaaat atcagatatt gcccgacaaa gggcgaatct ctgcggcaca agccaagaca
    46501 aaggcagaaa gcgaatacga tatttttaat aaaacccaac ggattgattc tgacttcgat
    46561 aaagaagtta ggggaatgtt gggtgaataa tatagatata gtatgacaga agacgaaaaa
    46621 cttatccaag aagtacagga tcaatgcgag tattttgcaa aaggcatcat aaacagtctt
    46681 tgtaagcgag ccattcgtaa aataaactcc tggaacattc acataggtac agatgattat
    46741 ccttcttcgt ttaacttttt taatattctc tcaatagagt accaaagcaa gtgttacgat
    46801 gaaatatcac cctgcttaga ggacgccata gagggggtat tggacaatga gtacgagaaa
    46861 ctattgccgc aagagcggtt ctttgtggat tatagccaat gctattatga taacgaattt
    46921 gactctgagt ctattaaaag aaagatatat gaccgcttct acgaaattct caacgagcat
    46981 tgggagtcaa agaaaatagc taattttgaa gaaaaaagaa actggtaata aaactacaaa
    47041 agtaaatata tacgattaga tataatgact gaaattaaag aatttcttaa aagtgaaacc
    47101 aaaatatcaa aagattgccg agtgaaatat tggctattct gtaaaatctt ggattattta
    47161 cttgccaatc aattttatat tggtaaggac tatgtatcat ataaggacat ccatacgtat
    47221 cttgacaaac aatgcacatt tgactatatt gactctattc atgcacaaac tgaactttgg
    47281 gtccatgaaa tgttatggtt gggtctcatc aattttgatg aaaactcaca gcaaatgtct
    47341 ctcacaccag aaggcgcatt accgggattt gccttcacca aagccgtaaa ttctt
//
LOCUS       DBMDTB010000018        45981 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_320_length_45981_cov_11.739320, whole genome shotgun sequence.
ACCESSION   DBMDTB010000018 DBMDTB010000000
VERSION     DBMDTB010000018.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 45981)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 45981)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45981
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_320_length_45981_cov_11.739320"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..229
                     /locus_tag="ACZPB4_04910"
     CDS             <1..229
                     /locus_tag="ACZPB4_04910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097597.1"
                     /translation="TLGYTLPKSILDKIKFEKIRIYGQIANVFTLTGYSGLDPQVRTD
                     TDGRSNDRTMGTDFGSYGMPRQFIMGVNVTF"
     gene            261..2120
                     /locus_tag="ACZPB4_04915"
     CDS             261..2120
                     /locus_tag="ACZPB4_04915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0019867 - outer membrane [Evidence IEA];
                     GO_function: GO:2001070 - starch binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RagB/SusD family nutrient uptake outer membrane
                     protein"
                     /protein_id="HIR1097598.1"
                     /translation="MKNLFIYAAVIAATMGSMTACSDFLDVKPVTNKQEPDFVSQEGI
                     TQLLTGMYARLNSTDANDGYFRSTLTNYVYGDVMGGDANKGSTFQDQPDFTSLETYTF
                     TTDNAYFETKWAHSYHGVFTANNVIKVADLAKEELSAIAGQSKDFYTETIAQARFIRG
                     FFHFEVVKLFGAAVPYVDDIAMKENVNPQVSNVDENGNYIYIWDKIVEDLQFAYDNLP
                     DTWTEAGRVNKWAAGAMLAKVKMYQSSPYNGKNGTSNHWTEVKTILEDVIANGKDNKG
                     TKFRLADTYEELYTAGESDWTGESVFDVQAAVSGTVEQTANINGAWHIGFSGALGTGG
                     WGFYQPSYDMVNAHIVDANGLPKMDDSYRNDPALSTLDENNLPHTDLTVYTDPRLDVS
                     TGRFETPFLDWTVPNALDGWVRDVSNGGLYLNKKNIPRKADKGSLSNTTQTNSTAKNF
                     HLIRYADVLLWYAETLIELGQPQQAGEYINQVRARAANSYVKAVDPATMTEASSTYVL
                     DDKINGKQSTDAAANYRIGLYPPSQFASKDKALEALRWERRIELAMEGHRWYDLARWG
                     IASEVLNDFVKYEAKHLGKYSNSTYNAKWATMPIPHNEILKMDGLLVQNENWK"
     gene            2350..4095
                     /locus_tag="ACZPB4_04920"
     CDS             2350..4095
                     /locus_tag="ACZPB4_04920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6057 family protein"
                     /protein_id="HIR1097599.1"
                     /translation="MRYKQILLGLILFVLLGGFLQITGKFHFFYIEQLQLFQFSEDYL
                     ADKISSPGGLSLIIGEFLTQFFITPYAGPFIIAAILTSIGLTMREIILQINPNKELFL
                     LYLLPVLFLLLIQYDFNYLVQGTIAFLFCLISLNAWMRIKDPCYRLSAALVITPLLFW
                     IGGPIAGLFSLSVVLKEAISRSKQGFYFLAVLIEYLFIGIGSVWSTTITSYRFAFLPD
                     AFYHPILAAPNLIYFAWVCLPLSLIGAFVYPKGKNQSKKKTGIELTVQFILILFLCWV
                     TIPRYNDQKAYPLKVLDYYARTEQWDEIIRHCHGPIKNYLYLTYLNRALAEKGELADR
                     MFAFDQHGPQGLLASWNKTFTVSTLLSDAYFTLGEIALSQEMAFEGYVTVIGAGNPRN
                     LQRLVQTNLIYGTYPIAEKYISILEKTYAYHDWAKRHRGFLYNDKAIEADPVLGPKRK
                     ALPKESNLSGINGLEHDLLIRAEQDPENQLPIQFTGAIYLLSKDMKAFQRLIEKYYGT
                     PVLPSLPVSFQEAVILLAEKDVDYWKRFNVSGNVIRKFAGYRNLVVQNRNNPQLPQLI
                     KKSFGDTYWSYYTLK"
     gene            4105..5571
                     /locus_tag="ACZPB4_04925"
     CDS             4105..5571
                     /locus_tag="ACZPB4_04925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009016931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolB family protein"
                     /protein_id="HIR1097600.1"
                     /translation="MKRNILYITCLFLILLGISCSDTIPVSKETSEKPVLFPDYADVT
                     IPYNIAPLNFKIENPHAEAFAVLKFGEEKIQVKEKGGQFYLPASDWRKLLKRATGKAI
                     QVKLYAKDKEWLAYPEFSLFVAPEPMDSYLAYRLIEPGYELWNQMGIYQRNLEDYKQS
                     PIMENKYSGQNCMNCHSFCMQNPDKMLFHMRDKYSGTYLIDGDKIEKLNTKTDQTISP
                     LVYPSWHPSGKYVAFSVNQTSQSFHANDKNRVEVFDSQSDVVVYDTEKHEIISTPSIR
                     TAKAFETFPTFSPDGKTLYFCSAEARSMPHEYSEVKYNLCSIAFDPVTRSFGSRIDTL
                     YNAGKDGKSASFPRVSPDGKFLLYTLSGYGNFSIWHKDADLYLLDIASGISHSLQNAN
                     STDTESYHSWSSNSRWIVFSSRRIDGLYTRPYFAYIDEEGNASKPFLLPQKDTDYYHR
                     FMKSYNIPEFITGKVSSKIRALSTLAKEDKGIDVTYRK"
     gene            5582..7354
                     /locus_tag="ACZPB4_04930"
     CDS             5582..7354
                     /locus_tag="ACZPB4_04930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6057 family protein"
                     /protein_id="HIR1097601.1"
                     /translation="MSTLYKKILPPLPFILLTGVLWFHLQTMQEPLFFYREQQQIFLF
                     DSTYIFSILKQIGGLATFISQFLIQFFRIPLIGSLVTALIGGISGWLFWLTLRKIHPA
                     LYLMPLAFLPILFQYLYLMKDSYHYEGLIAMLFWSLALNVYSYSARRFNWTYRTLIGC
                     LLATGLFYTMGSVAILFALSILLFDVLQKCERWYASFIPLLLLLIVGSLCVLGGSKPD
                     YDYVFWMKDYVEYFIELEPFYGFSWQVALLVMLLFFLSRYLDHIKTYLKALVAVALLA
                     LSGMYYTQTALQQRNKDFYTLMQMFHYIDTEQWDAIISSTDLNYNNYLHLNCLNLALS
                     HKGVMQTDLFKYPQSGIQSLVSKYQAHIEESFLFSQIYYHVGITSLAYNFAFGTSVGI
                     TYGSPVMTKLLIKSHLIYGQYPAAEKFISLLEKTWAYHEWASSQRKFLYNDQAVESDP
                     ELGTKRKSLSNDKDLFANIIGLFDNLMIILEKNPQNKAALDYTIGTLLLSKDLPAIKT
                     FVERFSGTEVLPALPEPLQQAVISYAEHDPEYCRKYGVTDKILSEFSIFKQRVLGLRH
                     ARQNVATGIADYQPTFWYYLILSK"
     gene            7362..8840
                     /locus_tag="ACZPB4_04935"
     CDS             7362..8840
                     /locus_tag="ACZPB4_04935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolB family protein"
                     /protein_id="HIR1097602.1"
                     /translation="MERQTYTNTNRYLFLFLIALMVSCSKSDIQIAKSLNKEIAIYPD
                     YKDVTIPVNIAPLNFSIADSSEHCLIIKGEKTQLQVYSDEGLFEIPQKRWKALLKENA
                     GNQIELTIAKRIQGEWNAYTPFHMDIVNDSIDKYIAYRLLALSNDMWNRMGIYQRNLE
                     NYDQSVIYENSLTDYNCVNCHTFSSGNPDKMIFHMRGKHAGSVLIDGKKITKLNTKTP
                     ETVSNFVYMYWHPNGNYLAATVCDTYQNFFINNPNTLEVLDHNSDIVIYDVKKNEVFS
                     CEALNSKDAWQIFPAFSPDGKSLYFSSTAAVDSISKNFRQMTYSLCRVDFDPETRTLG
                     QQVDTLYNGRANHKSVSFPRISPDGKYLAFTLQEYGGFGVWHKDAELYMIRLSDGKTY
                     PLTEANSAEGESYHSWSHNNRWLVFSSRRLDGLYTRPFFTYIDDKGTAHKPFLLPQRN
                     PVKYYKNLLWTYNLPEFIQEKVQVDTHAVMETMRNTKGIHVK"
     gene            complement(9195..10376)
                     /gene="purT"
                     /locus_tag="ACZPB4_04940"
     CDS             complement(9195..10376)
                     /gene="purT"
                     /locus_tag="ACZPB4_04940"
                     /EC_number="2.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009016928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate-dependent phosphoribosylglycinamide
                     formyltransferase"
                     /protein_id="HIR1097603.1"
                     /translation="MVTIGTPKSATATKVVLCGSGELGKEFVIELQRYGVEVIALDKY
                     PDAPAMQVAHRSYVVSMLDGDALREIIEKEKPDYIVPEVEAIATRTLMELEEEGYHVI
                     PTARATWLTMNREGIRRLAAEELGLPTSPYRFAETEEEFKEAVKVIGMPCVVKPIMSS
                     SGHGQSVVREEKDIDRAWQYAQEGGRAGAGKVIVEGFVDFDYEITQLTVRHIGGTSFL
                     EPVGHVQVDGDYRESWQPQAMSLAAKAKAREIAGKITEALGGRGIFGVELFIKGDDVI
                     FSEVSPRPHDTGMVTMITQDLSQFALHARAVLGLPIPNIVFHGAGASRAVVVEGDSDR
                     LSLGNLDKVLEQPDTQMRFFGKPEVHGHRRMAVLLARGLDVTEAREKTGVMMEQLNVK
                     L"
     gene            10812..11495
                     /locus_tag="ACZPB4_04945"
     CDS             10812..11495
                     /locus_tag="ACZPB4_04945"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008154416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1097604.1"
                     /translation="MIQLKGINKTYFNGAPLHVLKGIDLDIEKGEMVSIMGASGSGKS
                     TLLNILGILDTYDTGTYLLNGQLIQNLSESRAAELRNRMIGFIFQSFNLISFKNAVEN
                     VALPLYYQGVSRKKRNAMALEYLDMVGLKDWADHMPNEMSGGQKQRVAIARALIAKPQ
                     IILADEPTGALDSTTTVEVMELLRSVNQEGMTMVIVTHEPSVAEATDRIIRVKDGLIE
                     YTVNEESHV"
     gene            11488..12765
                     /locus_tag="ACZPB4_04950"
     CDS             11488..12765
                     /locus_tag="ACZPB4_04950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1097605.1"
                     /translation="MFDFDNFREIWSTIKKNKLRTFLTGFAVSWGIFMLITLLGAGNG
                     LRNGIIFNFRRFSANTVEVWGRYTTMPYKGNPTNRRIEFKEADLSGIKMAFPEIEYCS
                     ATISQTDTISYGEEYIVGDLRGVSEDYNSIIYINVASQNGRFINKMDMNATRKVIILS
                     PRMAEVLFRNEDPLGKYVKCGNMMYQVVGIYDDDDKSNNAPAYIPFTVAQQLYNKGFG
                     FGSIYFTVNGVSTEEECKDFENRFRSYMARKHIFDPTDKNAIGMWMTGNEIRMFNTMT
                     DGILLFIWIVGIGTLMAGIVGVSNIMLITVRERTREFGIRKAIGAKPASILKLVIVES
                     IMITAIFGYIGMLMGIGLTELIDYGMTMSGMNNASSGGNPGEDLTLFRHPTVSLGISL
                     AATGVLVVAGVLAGYFPARKAVNVSAIEAMRTE"
     gene            12777..14033
                     /locus_tag="ACZPB4_04955"
     CDS             12777..14033
                     /locus_tag="ACZPB4_04955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1097606.1"
                     /translation="MFDIDRWTEIWVTITRNKTRSLMTCFGVFWGILMLVLLLGTGSG
                     FKNAMFKSVNGFATNSLFFYADRTSEPYQGFNKGRNWNMRNRDIDAIIRDVPSVQDIS
                     PILWGSRSEKNIVYGIMTGTFNVKGIYPAYFNIDTQDLYYGRLLNEIDMREKRKVCLI
                     GTKINEVLFHNEDPCGKYIRVNGLYYQVVGVVNQRASGLNLGGRGEETVFIPFNTMQQ
                     TLNQGDILHFLALSVKPGYPIETTIEQVKNIMKTQNQIAPTDPQAIGVVNIAAQFKTF
                     NLLFTGIDILVWLVGMGTLLSGIIGISNIMMVTVKERTREIGVRRALGAKPFDIISQV
                     MSESLVLTALAGLLGLSAGVFLLDLLDKILSANPTNDPTLLNPGVNIQTAVAAAVVLL
                     ISGFMAGLIPAWRAMQIKAIDAIRDE"
     gene            14069..15190
                     /locus_tag="ACZPB4_04960"
     CDS             14069..15190
                     /locus_tag="ACZPB4_04960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HIR1097607.1"
                     /translation="MKNRIVKKILRIILLTIVGAAVIGTFYFLWKKAQPVITVYEVVT
                     PKRDTVETKTVATGSVEPRYEVEIKPQISGIISELRKEAGQMVQAGEIIATIKVIPEM
                     VQLNSAESRVNIADISLKQVEETYKRDELLFKQGVIAQEDFDLSKANYLKAVEEKENA
                     QSALEIIRDGIAKNSNVASTTQIRSTITGMILDIPVKVGNSVIQANNFNDGTTIATVA
                     NMNDMIFKGNVDETEIGRIHEGMPIKLTIGAMESRSFEALLEYVSPKGVEKNGAIQFE
                     IKAAVTIPEDAFIRAGYSANAEIVLKRAEDVLTIPESTVEFQGDSAFVQLVKQEQPEQ
                     VFEKHPVKVGLSDGIKIEVQEGLAATDKVRGAAIDPNKK"
     gene            15203..16561
                     /locus_tag="ACZPB4_04965"
     CDS             15203..16561
                     /locus_tag="ACZPB4_04965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HIR1097608.1"
                     /translation="MMRRNLYILAIASLLSGNYVFAQDAVKQWSLEECIQYAIEHNID
                     LKQKEQEQESRKVDLHTSKYSWLPALNGSLGQSFQFGRSTSKSGVIVDQNAANSTLGI
                     NLDMPLFDGLKIPNDIAARKLDLKASIENLNKAREDLSINIASYYLQVLYNKELLKIA
                     QLQVELDKEQVNKTEAMVNAGKVPLSQLYDIKAQLAKDEVTLTESQNNVNLALLDLAQ
                     SLELERSDRSFDIQTPVIEDAVADNMSSILPPENIYDHAVTFKPQIKEQQYLLESQKK
                     MLRVAQAGYYPKLNFGASYSNGYYHSTSGGEFADTRSFSEQFKQNGQKIVGFSLSIPL
                     FNRFQVRNSVRTARINIINRELLMENTKKTLYKEIQQAYYNATASQEKYTASDKSVTA
                     SKEAFNYAQERYNAGKSTVFEFNEAKTKYAQSLAEQAQAKYDFIFRTKILDFYNGNPI
                     RL"
     gene            16978..20193
                     /locus_tag="ACZPB4_04970"
     CDS             16978..20193
                     /locus_tag="ACZPB4_04970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SusC/RagA family TonB-linked outer membrane
                     protein"
                     /protein_id="HIR1097609.1"
                     /translation="MKHKLTLVLLSFFLGVQCMVAQQMKVTGVVINEDDGEPVIGASI
                     VVKGTTIGTITDLDGKFELETQKDAKLIISYVGLRTQETTAQQNMRIVLSSDSQAIDE
                     VVVVAYGTAKKSSFTGSASTVGAALMDKRPLSNALSALEGNTSGVQMTSSIGQPGEAA
                     KVTIRGFGSVNADNAPLYVVDGAIFSGDISSISPSDIESMTILKDAASTSLYGSSAGN
                     GVVLITTKKGSSSSGAGVTLSISQGWSSRAYNDYAKVGVYDYYPLQWQMLRNANMSLG
                     QSATDAAANASKDIINKLKYNPFVGIANDAIVGTDGLLNPSASALKWGEDLDWEDAAY
                     RTGHRQEYNVSYNTKTEKSDTYASIGYLNDKGYMIKTDFERYNARLNYNIYPVKWFKS
                     GLNLGLSRTNSNYSTSTSSNSAGYGNLSRFIRSMAPIYPVHKHDIETGAYLDKEGNVV
                     TDPALYTYDYEGARISSNGRDGIAEALWNDRLMSTTNSSARTYVTITPIEGLNLTVNY
                     AFDNKDERRRVYENPEVGDGTAGPGRLNIRNRNFLTQTFNQLINYTKTFGKHNIEALL
                     GHENYSYRLQYNYGMKTNEIVSGTYEYSNFVSISSMDSYTREYKKEGYFARLNYDFDD
                     KYYVTASYRRDGSSRFSKDNRWGNFWSFGASWRISQEDFMENLTWVDNLKLRASYGET
                     GNDAIYYTDDDTQQDYYPYQTLYNLGINNGLEAGLYFPTMANNNLKWETQVSTDVALE
                     FGLFGRLNGTVEFFRKASRDLLFNVSQPLSSGVEKIVQNIGKVRNQGVEIDLNYQVLK
                     SKDWKLSVGANATFINNKVTRLPDANRKDGIIKDSKKLMEGHSIYEFWLRQWWGVNPD
                     NGDGLYIFDAENNTDANGNIKDAVKKTLVEKDGQVLTNSYSYAKYDFSGSAVPKVYGG
                     FNINLSYKAFDLSTVFSYSLGGKVLDSSYRGLMDVGEFGYAMSPDLHNAWTTPGQITD
                     VPRLDNNSGHATSIGQSYSTRWLTNANYLNLRTVTLAYNLPKSILNVINIKSARVNVS
                     AENLFMLKARQGLNPQANYAGVSYNEYMPAKNFTIGLNVSF"
     gene            20224..21744
                     /locus_tag="ACZPB4_04975"
     CDS             20224..21744
                     /locus_tag="ACZPB4_04975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RagB/SusD family nutrient uptake outer membrane
                     protein"
                     /protein_id="HIR1097610.1"
                     /translation="MKNIQLFKHIAAGLLLSGSLIGTSCSSDYMDTIPTENVSFTTVS
                     TSLDNLYLALNGIHRKMVSQDLGNQGLGGEPGFIIGREALADDLTWDTQTWHQGFLNW
                     SYPTNATSSYNSGEWETYYKFILNANNILKALNDNFSDESKLTDSEKALANHIKGECL
                     AIRAWSHFNLVQYYAKPYRNGQDNSQPGVPYRTSPEIEPMARNTVEEVYTKIHGDLDE
                     ALNLLADYEPNDKNHYSLASVYGLKARALLTQQKYADAATAAVNSINEAEKDGCKIMS
                     QSELMNGFANITSATKEAMYAAMTQNDQTVYFYSFYAYMSWNFNSSSIRTGIKCISQS
                     TYDLMSPTDLRRQWWDPTGKAEVPATSYNQRVYQNRKFTARSTADAVGDFAFMRISEM
                     YLTAAEAFARSNQDAKAKEYLQALLKERDPEYKDLGNTGAKLADEIMTHRRIELWGEG
                     FRWFDLKRLGLPLDRTGSNFDATFCGFLHKDPNADGWIFEIPKKETDFNDLIEKNY"
     gene            21832..24249
                     /locus_tag="ACZPB4_04980"
     CDS             21832..24249
                     /locus_tag="ACZPB4_04980"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase family protein"
                     /protein_id="HIR1097611.1"
                     /translation="MKTNHLFSALLSLALICPGIAQETHYQRPPAVIEEVALAKLSPI
                     IRISDNNQWALQLERSPYRSIAKLAQPELKLAGMRISPETFNTSRQAEYTGASLMNIA
                     TQEEIKIEGIPDNAVITEASFSPSSNKVALFVEEANGVYLYNCTPEQPVAQKVSTRKI
                     NATSGAEILWISDNEFITLMVPENRGKAPEKPTVPSGPIIQESTGKVMPARTYQDLLK
                     NPYDEQLFDYYFTSQLVRIKEGIVYEIGKPAIYGSTLSLSPDKSLLLIATVHRPYSYQ
                     VPVYNFPQKFEVIDLQGNSIYTLADNPTVNIPMGYDTTSPYPRQFGWRSDQPATVYWA
                     EAQDKGDPKQNKTDFMDIIYQISYPFNSEKQEVAKTEKRFRNILWNDDAFALLIETSR
                     ETRKNRTFTFKPCSSESPVLLFDVSTDDNYNNPGNPLTIKNAYGKYIVYTNKAHNELL
                     MLAQGASSKGDMPYLSRYNLKTKKNTELWRCEDGYYETILKVANPEKLQLITSRQSIT
                     EPANLCSRDLKKKKFAQLTHFANPYPAMANVSKQKIKYKRADGLDLTATVYLPAGYDK
                     AKDGPLPVLMWAYPREYKSKAEASQVRGSQYMFTNINYGSPVYWVLRGFCIMENVEMP
                     IVSTSEGAEPNDDFIEQLTMNAEAAVKVISEMGVGDPNRVAVGGHSYGAFMTANLLTH
                     TKLFKAGIARSGAYNRTLTPFGFQTETRTYWEVPEIYNAMSPFMSADKLHGALLIIHG
                     EMDNNSGTFPIQSERLFSALKGHGAIARYVVLPYESHGYAAKENILHLLYECDLWLDR
                     YVKNAKK"
     gene            complement(24477..25280)
                     /gene="nagB"
                     /locus_tag="ACZPB4_04985"
     CDS             complement(24477..25280)
                     /gene="nagB"
                     /locus_tag="ACZPB4_04985"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009131680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004342 - glucosamine-6-phosphate
                     deaminase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HIR1097612.1"
                     /translation="MIEPNYEQLSKWAANYVAAKIKAANPTAEKPFVLGLPTGSSPLG
                     MYKNLIELNKQGVVSFQNVITFNMDEYVGLPKDHPESYHSFMWNNFFSHIDIKPENVN
                     ILNGNAEDLEAECASYEARMKAVGGVDLFLGGIGPDGHIAFNEPGSSLSSRTRIKTLT
                     TDTIIANSRFFDNDVNKVPKTSVTVGVGTVLDAKEVLIMVNGHNKARALQQAVEGAVN
                     QMWTITALQLHPKGIIVCDEAACADLKVGTYNYFKDIEKDHLCPCSLLK"
     assembly_gap    25283..25382
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(25533..26744)
                     /locus_tag="ACZPB4_04990"
     CDS             complement(25533..26744)
                     /locus_tag="ACZPB4_04990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FprA family A-type flavoprotein"
                     /protein_id="HIR1097613.1"
                     /translation="MYKLKEIADKVYYVGVNDRQKALFENMWPLPYGVSYNSYLIVDE
                     KTVLIDTVDVCYSDIFLKKVADALDGRSLDYLVVNHMEPDHAGSIRLLRQQYPDVQIV
                     GNNKTFGMLEGYHGIKEGLFEVKEGDTLNTGRHELVFYMAPMVHWPEVMVTYDVTDKI
                     VFSADAFGTYGTLDGGVIDTEMNVEHYWEEMIRYYSNIVGKYGSPVQRALQKLSGLDI
                     QTICSTHGPVWREYASKAIDIYDRMSRYEGEEGVVIIYGSMYGNTEQMAEAIAASLAD
                     NGIKNIVMHNVSKSPSSYILKDVFKYKGVIVGSPTYSNQLFPEVEAVLSKIELREVKN
                     RIFGYFGSFTWAGAAVKRLAAFGEKMKWETVGTPVEQKQGLSATKYEECLALGKEMAG
                     KLKTINDKSNL"
     gene            complement(26807..27640)
                     /gene="lgt"
                     /locus_tag="ACZPB4_04995"
     CDS             complement(26807..27640)
                     /gene="lgt"
                     /locus_tag="ACZPB4_04995"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HIR1097614.1"
                     /translation="MLDFITWTADPAIFTIGSREIRWYGLAFAIGFAIGYMIVERMWK
                     KEGLPPAWIDSLLIYTMLGTVIGARLGHCLFYAPEYYLANPIEIFKIWEGGLASHGGT
                     LGIIIAIYFYSKRVSHKSMLWAFDKLVVPTGLVAAMIRLGNLMNHEIYGHSTDLPWGF
                     RFIDNLHAWRMGAEPIFTAPSHPTQLYEAACYLVTFAICMWLYFKKEAWKKQGLIFGV
                     FMICVFGSRFFIEFVKNDQEPFEAGMMLNMGQWLSIPFVLAGCWFVWRALRNGKLKIE
                     N"
     gene            complement(27736..28632)
                     /locus_tag="ACZPB4_05000"
     CDS             complement(27736..28632)
                     /locus_tag="ACZPB4_05000"
                     /EC_number="1.4.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047850 - diaminopimelate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate dehydrogenase"
                     /protein_id="HIR1097615.1"
                     /translation="MKKIRAAIVGYGNIGKYVLEALEAAPDFEVAGIIRRNPNDIPDE
                     LKAYTVTDSITKLDKVDVAVLATPTRSVEEHAKEILALGINTVDSFDIHGGIVDLRRS
                     LDAVAKAHNTVAVISAGWDPGSDSVVRALLEAMVPKGITYTNFGPGMSMGHTVAVKAI
                     EGVKAALSMTIPLGTGVHRRMVYIEVEDGYDFKQVSAAIKADDYFAHDETHVMQVECV
                     DNLLDMGHGVNLVRKGVSGKTQNQLIEFDMKINNPALTAQILVSVARASLKQQPGAYT
                     MIELPIIDMLYGERENLIRRLV"
     gene            complement(28736..29737)
                     /locus_tag="ACZPB4_05005"
     CDS             complement(28736..29737)
                     /locus_tag="ACZPB4_05005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HIR1097616.1"
                     /translation="MSVRKWMFAGALLLAAGLSSLGFAQKPGLKFNPDKKFKIVQFTD
                     LHVKWQDPRSDIAFERMNQVLDDEKPDLVIFTGDIIYSKPALENMRNVLKTVSDRKIP
                     FSIVFGNHDNEQGATKEELLKVAESLPYSLTADEVPEISGVGNYALTVRSSDGKKDAF
                     VLYCIDSNTYSTIKGVKGYDYIKRDQIDWYCKKSAEFTRNNGGEPVPSLAFFHIALPE
                     FNQAASDENAQLYGIRREKACAPALNSGLFTAIKENGDVMGVFVGHDHDDDYAVCWYD
                     VLLAYGRFTGGPTEYIHIPNGARVIELNEGARTFKTWIRTKAGVEQLTTYPDSFVKE"
     gene            complement(29770..30762)
                     /locus_tag="ACZPB4_05010"
     CDS             complement(29770..30762)
                     /locus_tag="ACZPB4_05010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HIR1097617.1"
                     /translation="MARPVTLYTLQWGDLSLETVCQKAKEFGYDGVELGLPDHVDVRR
                     TDTAYYQGIKDLLKKYDLRLYAISTHLVGQAVCDNIDERHKAILPDYIWGDGDPEGVH
                     QRATEEMIRTAHAAKMLGVDTVVGFTGSSIWHYLYSFPPVTDAMIQKGYDDFARRFTP
                     ILDEFQKLGVRFALEVHPTEIAFDTFSARRALEAVNNHPAFGFNYDPSHLGYQGVDYV
                     DFIYQFPERIFHVHMKDVYWSDTPKQVGIFGGHVTFGDPRRYWNFRSLGRGKINFEEI
                     IRALNSIGYQGPLSVEWEDSAMDREHGARESCELVKRVDFQPSAHAFDACFGKE"
     gene            complement(30777..31931)
                     /locus_tag="ACZPB4_05015"
     CDS             complement(30777..31931)
                     /locus_tag="ACZPB4_05015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family protein"
                     /protein_id="HIR1097618.1"
                     /translation="MKRKIRMGMVGGGQGSFIGAVHRIAANLDGQIELVCGCFSSRPE
                     NSLATGQSLFLPDNRIYASYQEMIEKEATLPEGERMDFVSIVTPNHVHFGPAMMALEH
                     GFHVVLDKPMTYTLDEAKQLRDKVKETGKLFMLTHTYTAYPMVKEARERVRRGDLGKI
                     RRIYVEYPQGWLYNDCADVNKQAAWRVDPNRSGKAGCMGDIGTHAFNLAEYITGLKAV
                     ELCGELNTFVPDRLLDDDGAALIRYEGGAKGVLTASQIAVGVENGLNIRVYGEKGGLE
                     WRQEEPNTMIMRWPDRPAEIIRTSNGYMSGIAAHNSRTPGGHPEGYIEAFANLYRNFA
                     LALRSILAGEEPAPETLDFPSAEDGVRGMRFIETIVATGSTENKWIKIID"
     gene            32088..33047
                     /locus_tag="ACZPB4_05020"
     CDS             32088..33047
                     /locus_tag="ACZPB4_05020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097619.1"
                     /translation="MKKKELVAIACLLCFCCCNGTEKEVPNPDLQEELSPIQFTIDLQ
                     KEVLPFPVTKSIPELNIPEPIPQNPDAEEDPSTPDIDPDNLYNRIDYIVYQSGKPDIL
                     VKHKQFTPQDPDFTIIYDSLPSGNYHICFLAHSDKNISVSGQTALFSKVSDTFHLFLT
                     QEVQTGERIIKDITLQRIVGKIEFISADGVPKALKSFTINVSNYQNKIDLTTGNGISQ
                     NTPYTQTDTFNDSDIGKTNFSHSFFTFIPAPEFMLKAHLSAKNQINEVTREREVNDIL
                     PLINHIIRYTGILYTPKESDDTFTLDILNGGKWDSPIDKDLKD"
     gene            complement(33105..33416)
                     /locus_tag="ACZPB4_05025"
     CDS             complement(33105..33416)
                     /locus_tag="ACZPB4_05025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043856 - anti-sigma factor antagonist
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="STAS domain-containing protein"
                     /protein_id="HIR1097620.1"
                     /translation="MEVVIDQKGEETVIKIKGRLDTNTARECEEKVLPVWENPGVKVC
                     VDCSDLEYVSSAGLRLFLILQKMTTAKKGSLRLIGMRNVVRETFSLTGFNALFKIEDA
                     K"
     gene            complement(33428..33841)
                     /locus_tag="ACZPB4_05030"
     CDS             complement(33428..33841)
                     /locus_tag="ACZPB4_05030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012056072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HIR1097621.1"
                     /translation="MQKTLRIKNDIHELSMMNQFLEEAGEELGLSTAFMMSLNLVMEE
                     AVSNIIFYAYKGDVEDAVDISLVREGGELIVTLIDHGIAFDPTLRKDPDITLSAEDRP
                     IGGLGIFLIKKIMDEVSYQRVDERNVFIMKKKITE"
     gene            33939..34352
                     /locus_tag="ACZPB4_05035"
     CDS             33939..34352
                     /locus_tag="ACZPB4_05035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097622.1"
                     /translation="MAKRYLINIFLLIAVLCGFSSCEEDPYYDPYEEITYDLCNYVWT
                     DWFVVDGLDCEQQLTFNPDGKGWDTRIYHYPSGRIDREEIPFYWDWNNYYTDILYMDY
                     EDGQTTLENVWISGRTFKCLYNGEWVTFKAYQIGL"
     gene            complement(34442..34513)
                     /locus_tag="ACZPB4_05040"
     tRNA            complement(34442..34513)
                     /locus_tag="ACZPB4_05040"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(34478..34480),aa:Arg,seq:cct)
     gene            complement(34701..35426)
                     /gene="recO"
                     /locus_tag="ACZPB4_05045"
     CDS             complement(34701..35426)
                     /gene="recO"
                     /locus_tag="ACZPB4_05045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005650583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HIR1097623.1"
                     /translation="MLCKTRGIVLHAIPYNDKYSIIYMYTEAFGRASYLVSRSRGKKS
                     TVSKALFIPLSVLEMEVEHLNKRDLHRIKETRICFPLNDVCCDPVKNVLALFLSEVLF
                     RVVKDTEPDPRLFDYLCESIHLLEYADKGIANFHMVFLLGLLHHLGIFPNMESHRVGY
                     YFDMLNGVFTDHIPMHRHYLNKVESAFFSRLLRISFENMSLYGFSRQERVRIIHRILE
                     YYRLHLPDFPEIKSLSVMQSLFD"
     gene            35504..35908
                     /locus_tag="ACZPB4_05050"
     CDS             35504..35908
                     /locus_tag="ACZPB4_05050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2721 domain-containing protein"
                     /protein_id="HIR1097624.1"
                     /translation="MLDLTTPSLLFSAISLILLAYTNRFLSYASVVRALKEKHQQTHD
                     PKDIAQIANLRKRLYLTRSMQILGILSLLLCVIAMFFIYVSWQIFAAWIFGIALLLLA
                     ASLCVCIWEINISVKALEIHLEDISSKEKLKQ"
     gene            36025..36096
                     /locus_tag="ACZPB4_05055"
     tRNA            36025..36096
                     /locus_tag="ACZPB4_05055"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:36058..36060,aa:Glu,seq:ttc)
     gene            36138..36392
                     /gene="rpsT"
                     /locus_tag="ACZPB4_05060"
     CDS             36138..36392
                     /gene="rpsT"
                     /locus_tag="ACZPB4_05060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HIR1097625.1"
                     /translation="MANHKSSIKRIRQTNARRLRNRYYAKTARNAMKVLRATEDKNEA
                     QALFPKVCSMLDKLAKKNVIHKNKAGNLKSKLAKHVNALA"
     gene            36461..36535
                     /locus_tag="ACZPB4_05065"
     tRNA            36461..36535
                     /locus_tag="ACZPB4_05065"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:36494..36496,aa:Glu,seq:ttc)
     gene            36707..38662
                     /gene="gyrB"
                     /locus_tag="ACZPB4_05070"
     CDS             36707..38662
                     /gene="gyrB"
                     /locus_tag="ACZPB4_05070"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HIR1097626.1"
                     /translation="MSEEIKNTSTEYSADSIQVLEGLEAVRKRPSMYIGDTSEKGLHH
                     LVYEVVDNSIDEALAGYCTYIDVVINEDNSITVTDDGRGIPVDIHEKEGKSALEVVLT
                     VLHAGGKFDKGTYKVSGGLHGVGVSCVNALSTYLKAEVRRNGKVHMQEFSCGKPLHDV
                     QVIDNTDKTGTTISFKPDGSIFTVTEYKYDILATRLRELAFLNAGITLRLTDKRVLKE
                     DGSFKSEVFHSDEGLKEFVRYIDRSKEKLIPDVIHIVTEKQGIPVEVALTYNTSYNES
                     VFSYVNDINTIEGGTHLAGFRRGLTRTLKKYAEDSKLLEKAKVEIQGDDFREGLTAVI
                     SIKVAEPQFEGQTKTKLGNSEVTGAVDMAIGEALGYYLEEHPKEAKIIVDKVILAAQA
                     RHAARKARELVQRKSPLTGGGLPGKLADCSSKDAAICELFLVEGDSAGGTAKQGRDRN
                     FQAILPLRGKILNVEKAMDHKIFESEEIQNIYRAMGVTVGTEDDPKALNMEKLRYHKV
                     IIMTDADVDGSHIATLILTFFFRRMRSLIENGYVYLATPPLYLCKKGKVEEYCWTEQQ
                     RQQFILKYGGGNENSIHTQRYKGLGEMNDHQLWDTTMNPENRTLKQITIDNAAEADQI
                     FAMLMGEDVGPRREFIEENATYANIDA"
     gene            38655..40439
                     /locus_tag="ACZPB4_05075"
     CDS             38655..40439
                     /locus_tag="ACZPB4_05075"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070573 - metallodipeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane dipeptidase"
                     /protein_id="HIR1097627.1"
                     /translation="MLKIMKVRRPNLEALYKEVDNYIPAKESLQPPRIGISANRRDGL
                     SCIAETYVQAVLDAGGAPVLIPVITDLKALTVLVSELDGLVMSGGGDINPLYLHEEPI
                     PQLQDVDTLRDEYDLILLRLAANRQIPIMGICRGHQIMNVAFGGSVYQDIHSQANHAL
                     LKHSQTLAREYPSHTVTLEPGMNRLRTIFNGEEQILVNSFHHQAVKEVAPGFRATATA
                     PDGINEAMEHTEKTIFGVQWHPEAMAPQGDEAMKALFAYHIENARRFAKAKAIHQRIV
                     TIDSHTDTPMIFPGEFNIGEKEGGKVNLPFMEEGRIDATFMVAYIPQGKRDEASLQAA
                     TAYAIERLNQVKRQQTLHPDRMVIATTPQEIRTIKAQGKKAICLGIENGYALGKLVEN
                     LRMFKEMGVSYITLCHNGDNDICDSARGKQEWKGLSPFGKEVVKEMNRLGIMVDISHA
                     AESTFYQVLEVSETPIIASHSSARALCDHPRNLTDDQLKALAAQGGVAQICLYKGFIN
                     KEEEKASLSDAIRHINHIVDLIGIDHVGIGSDFDGDGELIGCSATNELINITVRLLEE
                     GYTEEDIRKIWGGNLLRVMTAIQDFPNK"
     gene            40462..42312
                     /locus_tag="ACZPB4_05080"
     CDS             40462..42312
                     /locus_tag="ACZPB4_05080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fused gamma-glutamyl-gamma-aminobutyrate
                     hydrolase/peptidase"
                     /protein_id="HIR1097628.1"
                     /translation="MKNILYTAICACSILCGAQAQTPGSEVPNLKKLYELTDSCDVNV
                     RARFSPLIGISASISNGASRVGATYIQSIVKAGGTPIIIPAVTDGKVLRNIVSNLDGL
                     VLIGGADVNPLWYEEEPREKLEEVDPVRDLYELKLIKMATDQNIPVLGICRGLQLLNV
                     AFGGTLYQDIPSQRGDHSVKHRQDLPSSYGSHRVFVDANSQLASILGKDTLAVNSLHH
                     QAIKELAPIFKATAYAPDSIIEAIDAYPNRSIMGVQWHPEALTYGGDTTMLRIFRHLI
                     GKAETFHQAKEMHKHFLSVDTHTDTPFWFKRAGFSIADRERNRVNIPKMQEGKLDGVF
                     LAAFIGQGKRDEGSLQEAVQKVTGLIEGIRKQAELNKDLCGIAVTNQDFIRLKNEGKK
                     AFFIGIENGYGIGKDLANIAKFKAIGVNYITLCHSYDNDICDSSTHTKKEWDGLSPFG
                     EEVVKEMNRQGIMVDMSHASEKSFWDVIKLSKAPIICSHSSSMAMCKHDRNLTDEQLK
                     ALAQNGGVAQVCLLDRYINEDYKNASLTDAIEHIDHMVKVAGIDHVGIGSDFDGGGGI
                     IGCESDNDFIQITVKLIEKGYTEEDIAKIWGGNLMRVLDEVQATASVKTL"
     gene            42326..43315
                     /locus_tag="ACZPB4_05085"
     CDS             42326..43315
                     /locus_tag="ACZPB4_05085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HIR1097629.1"
                     /translation="MIRLFFALLSFALLSCGAKGTKETGNMPEIKKQPIASAVPDFNA
                     DSAYAYVANQVAFGPRVPNTAAHKACGDYLASELKRFGAKVYQQEAILTAYDGTKLEA
                     RNIIGSFDPENSKRVLLFAHWDSRPYSDHDPDPSKHRTPLDGADDGGSGVGALLEIAR
                     QIGQKAPGIGIDIIFFDAEDYGTPEFVTDYTPDSWCLGTQFWAKNPHVPNYTAEYGIL
                     LDMVGGKNATFFKEQQSLRAAAPIVEMVWSAARDLGYGKYFINATGGALIDDHQYVIS
                     GRNIPSIDIINYDPESKTGFASYWHTQKDNMENIDRETLKAAGQTVLEVIYNR"
     gene            43328..43753
                     /locus_tag="ACZPB4_05090"
     CDS             43328..43753
                     /locus_tag="ACZPB4_05090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SufE family protein"
                     /protein_id="HIR1097630.1"
                     /translation="MTINELQDNVIEEFSVFDDWMDKYALLIDLGNSLPPLDEKYKTE
                     SNLIEGCQSRVWFQADYVDGKIIFQGESDAVIVKGIVSLLIQILSGHTPQEILDADLY
                     FIDKVGLKEHLSPTRSNGLVAMVKQMRLYAMAYRAKEQQ"
     gene            complement(43871..>44431)
                     /locus_tag="ACZPB4_05095"
     CDS             complement(43871..>44431)
                     /locus_tag="ACZPB4_05095"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004309464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HIR1097631.1"
                     /translation="GCDEAGRGCLAGAVFAAAVILPEDFKNEDLNDSKQLSEKKRYKL
                     RPVIEREAIAWAVGIVSPEEIDKINILKASFLAMHRAIEQLKVRPEHLLIDGNRFTPY
                     PDIPHTTVVKGDGKYLSIAAASILAKTYRDDYMNELALEYPAYHWLDNKGYPTKVHRE
                     AIRTHGITPYHRKTFTLLPEQLTLGF"
     assembly_gap    44432..44531
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<44532..44917)
                     /locus_tag="ACZPB4_05100"
     CDS             complement(<44532..44917)
                     /locus_tag="ACZPB4_05100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HIR1097632.1"
                     /translation="MMYYIKKYPFSLAIILIVIYLSFFKPPRMDDIPLFPGVDKVVHF
                     CMYGGMSGMLWLEFLRNHRKYETVLWHAWIGAVLCPIVMSGIIEILQEYCTTYRGGDW
                     FDFLANTCGVIAATAFAWFVLRPWIV"
     gene            complement(44920..>45981)
                     /locus_tag="ACZPB4_05105"
     CDS             complement(44920..>45981)
                     /locus_tag="ACZPB4_05105"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0006534 - cysteine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HIR1097633.1"
                     /translation="NIHRGVHFLSQAATEAHEEARKTVQHFLNARSSNEIIFTRGTTE
                     SINLIASSFTDECMSAGDEVIVSVMEHHSNIVPWQIQAARKGITLKVIPMNEKGELNL
                     DEYRKLFSDKTRLVSVTHVSNVLGTVNPVKAMIEIAHEQGVPVLVDGAQAVPHMKVDV
                     QDLDAEFYVFSGHKIYGPTGIGVLYGKEEWLDKLPPYQGGGEMIATVSFEKTTFNELP
                     FKFEAGTPDYIGSTALAEALRYVDRIGIENIAAYEDELLRYATAGLNTIEGMRIFGQA
                     DHKGAVLSFLVGNIHHYDMGMLLDRLGIAVRTGHHCAQPLMHALGIEGTVRASFSFYN
                     TKEEIDTFIAGVERVRKMF"
BASE COUNT        13574 a        10675 c         9760 g        11772 t
ORIGIN      
        1 gactttaggt tatacacttc caaagagtat tttagataaa atcaagtttg agaagatccg
       61 catctatggt caaatagcaa acgtattcac attgactggt tactccggac tagacccaca
      121 ggttcgtaca gatacagacg gtcgttccaa tgaccgtacg atgggtaccg atttcggttc
      181 ttatggtatg ccacgccaat ttatcatggg tgtaaatgtg acattctaac aaatatttgc
      241 taactaaaaa ttgaaacaag atgaaaaatc tatttatata tgcggcagtc attgccgcca
      301 cgatgggaag catgactgct tgctccgatt tcttggatgt gaagccagtc acaaataaac
      361 aggaaccgga ttttgtatcg caagaaggta ttactcagtt gctaactggt atgtacgcta
      421 gattaaactc tacagatgcg aatgatggat acttccgttc gacattgacc aactatgtat
      481 atggtgacgt aatgggaggt gacgcaaaca aaggttcaac tttccaagac caaccagact
      541 ttaccagctt ggaaacttat acatttacaa ctgacaacgc ttattttgaa acaaaatggg
      601 cacatagtta ccatggggta ttcaccgcaa acaacgtaat caaggtagcg gatttagcaa
      661 aagaagagct ttcggctata gcaggccaaa gtaaagactt ctatacggaa acaatcgccc
      721 aagcccgctt catacgcggt ttcttccatt tcgaggtcgt aaaattattt ggagcggctg
      781 ttccttatgt agatgacata gccatgaaag agaacgtgaa cccacaagtc tctaatgtgg
      841 atgagaatgg gaattatatc tatatctggg ataagatagt agaagacttg cagtttgctt
      901 atgacaatct gcccgacact tggaccgagg caggacgcgt aaacaaatgg gcagctggcg
      961 ctatgttggc taaagtaaag atgtaccaat cctctccata taacggaaaa aatggaacgt
     1021 ctaatcattg gactgaagtt aaaacgattt tggaagatgt aatcgcaaac ggaaaagata
     1081 acaaaggcac taagttccgc ttggcagata catacgagga actctataca gcaggggaaa
     1141 gtgactggac aggagaatct gtattcgatg tccaagctgc agtttccggc accgtagaac
     1201 aaactgccaa tatcaacgga gcttggcaca tcggcttcag cggagcgtta ggaactggag
     1261 gttggggatt ctatcaaccc tcttatgata tggtcaacgc tcatattgtt gacgcaaacg
     1321 gattacctaa aatggatgat tcttatcgta atgatcctgc gttatcaact ttagacgaga
     1381 acaatttacc tcacactgat ttgaccgtct atacagaccc tcgtttggat gtttctaccg
     1441 gtcgtttcga gactccattc ttagattgga cagtgccaaa tgcgttggat ggttgggtac
     1501 gtgatgtttc taacggaggt ttatacctaa acaagaagaa tatccctaga aaagccgata
     1561 aaggaagctt atctaacacg acgcaaacaa actccactgc taaaaacttc cacttgatcc
     1621 gttacgcaga cgtattgctt tggtacgctg aaaccttgat cgagttagga cagcctcaac
     1681 aagcaggtga atacattaat caagtacgtg ctcgtgccgc caatagctat gtaaaggcag
     1741 tagatccggc aacaatgacc gaggctagtt ctacttatgt tttggatgac aagattaacg
     1801 ggaagcaaag tacagatgct gccgcaaact atcgtatagg tttatatcca ccttctcaat
     1861 tcgcatcaaa agacaaagcg ctggaggcac tgcgttggga acgtcgtatc gagttagcga
     1921 tggaaggtca tcgctggtat gacttagctc gctggggtat cgcatccgag gtattaaatg
     1981 atttcgtgaa atacgaagct aagcatttag gtaaatattc caatagtaca tacaacgcaa
     2041 aatgggcaac aatgcctatc cctcataatg aaatcttaaa gatggatggt cttttagttc
     2101 agaatgaaaa ctggaaataa acaagtgggt taacagtcag aaagggcagc cgggcatgtg
     2161 atatgtccgg cctgcttttt aatccccaaa agtaagttaa cttactttgc tcacgaagtt
     2221 aacatacttt gccaacgaag ttaactccat gtgccaatta agttaacttc gttttgtgta
     2281 gattggtatt tccgataaaa atcgtatctt tgtttgactt taaatcaaaa tgaaacgtgt
     2341 actctagcca tgagatataa acaaatactc ctcggtttga tcctgtttgt cctattaggg
     2401 ggtttcttgc aaataaccgg caagtttcat ttcttctata tcgagcagct tcaactattc
     2461 cagttttccg aagattatct tgcggataaa atcagcagtc cgggaggttt atctttgatt
     2521 atcggggaat tcttgacaca attctttatt acgccttatg cagggccttt cattatcgca
     2581 gctatactta cgtctatcgg cttaacaatg agggagatca tcctgcaaat taatccaaat
     2641 aaagagctct tcctgcttta cttactcccg gttttattct tattattgat tcaatacgac
     2701 ttcaattatt tagtacaagg cactatcgca ttcctatttt gtttgattag cctgaacgca
     2761 tggatgcgca taaaagatcc ctgttaccgg ctatccgccg cattggtaat caccccacta
     2821 cttttttgga taggaggacc gattgccggg ctattctcat taagtgtggt tctcaaggaa
     2881 gcgataagcc gttccaaaca ggggttctat tttttagcgg ttttaattga atacctgttt
     2941 atcgggatcg gaagtgtctg gtcaactacc atcaccagtt atcgcttcgc attcttaccg
     3001 gacgcttttt accacccgat tctggcggct cccaatctca tctatttcgc atgggtctgt
     3061 ttaccgctta gcttgatcgg ggcattcgta tatcctaaag gcaaaaacca atcaaagaaa
     3121 aaaacaggga tagagcttac cgttcaattc atcctaatcc tattcctttg ctgggtaacg
     3181 attccacggt ataacgacca gaaagcctat cctctaaaag tcttggatta ttatgcccgt
     3241 accgaacaat gggacgagat catccggcat tgtcacgggc cgatcaaaaa ctatttatat
     3301 ttaacttact taaatagggc acttgcggaa aaaggggagt tggcagaccg gatgttcgct
     3361 tttgatcaac acggtcctca agggttactc gcctcttgga acaagacctt tacggtctcc
     3421 accctgttaa gcgacgccta ttttacgcta ggggaaatcg cattatcgca ggagatggct
     3481 tttgaagggt atgtcaccgt aattggcgcc ggtaatcccc ggaacctgca acggcttgtt
     3541 caaacaaact tgatttacgg aacgtatcct atcgccgaga aatatatcag tatcttagaa
     3601 aaaacatatg cctatcatga ttgggccaaa cggcatagag gcttcttata taacgacaaa
     3661 gcgattgaag ctgatccggt attagggcct aaacgaaaag ctcttccgaa ggaaagtaac
     3721 ttatccggta tcaacggact ggaacatgat ttacttatcc gtgcggaaca agatccggaa
     3781 aatcagctcc cgatccaatt caccggggct atctatctgc tgtctaaaga catgaaagct
     3841 ttccaaaggc tgatagaaaa gtattatgga acaccggtac tcccctctct ccccgtgagt
     3901 ttccaagagg ctgttatcct attagcagag aaggatgtgg attactggaa gcgttttaac
     3961 gtatccggaa atgtgatccg caaattcgca ggttatcgga atttagtcgt gcagaaccgg
     4021 aacaacccac aacttccgca acttataaag aagtcgttcg gagacactta ttggtcttat
     4081 tatactctaa aatgatcaac aaccatgaaa agaaatattc tatatatcac ctgtttattt
     4141 cttattctac taggaatatc ctgctcggat acgatcccgg taagcaaaga aacctcggag
     4201 aaacctgtat tatttcccga ttatgcggat gtaacgatcc cttataatat cgctccctta
     4261 aatttcaaga tagaaaatcc acatgcggaa gccttcgccg tactcaaatt cggagaagaa
     4321 aagatacaag tcaaggaaaa agggggacaa ttctatcttc ccgcatccga ttggagaaaa
     4381 ttgctgaaaa gggcgacagg aaaagcgata caagtaaagc tctacgcaaa agacaaagaa
     4441 tggctcgcct atccggaatt ctcactattc gtcgctccgg agcccatgga ttcatatctg
     4501 gcttatcgct tgatcgaacc cggatacgaa ctttggaatc aaatgggtat ttaccaacgg
     4561 aatctggaag attataagca aagccctatc atggaaaaca aatacagcgg tcaaaactgt
     4621 atgaattgcc attctttttg tatgcaaaac cccgataaaa tgctgttcca catgagggat
     4681 aagtattcgg gcacttatct gatcgacgga gataagatcg agaaattaaa tacgaagacc
     4741 gatcagacga tctcgccttt ggtctatccc tcttggcatc catcggggaa atacgtagcc
     4801 ttctctgtca atcagaccag ccaaagcttt catgccaacg acaaaaaccg ggtggaggtc
     4861 ttcgacagcc aatccgacgt agttgtatac gatacggaaa agcatgagat tatcagtacg
     4921 ccttccattc ggacagcaaa agcgtttgag actttcccga cattctctcc cgatggcaag
     4981 actctttact tctgctcggc agaggcacgt tccatgccgc atgaatattc agaagtaaaa
     5041 tataaccttt gctccatagc gttcgatccc gtaacccgga gtttcggctc ccgtatagat
     5101 accttataca atgccggaaa agatgggaag agcgcctctt ttccccgtgt ttccccagac
     5161 gggaaattct tgttatatac gctgtccggc tacggtaact tctcgatctg gcataaagac
     5221 gcagatctat atctactgga tatagcgagc ggaatctctc attccttgca aaacgccaat
     5281 agcacggata cggagagcta tcactcatgg agtagcaaca gccgctggat cgtcttcagc
     5341 agtcgaagga tagacgggtt atacacacgt ccttattttg cttatataga tgaagaagga
     5401 aatgcgtcta agcccttcct tttgcctcag aaagacacag actactatca ccgtttcatg
     5461 aaatcttata atatacccga gtttattacc ggaaaagtat cctccaagat ccgggcactt
     5521 agcacgctag ccaaagagga taaaggaatt gacgtaactt atcgtaaata gaataaatca
     5581 catgagtact ttatataaga agatattacc accgcttcca ttcattctat tgaccggcgt
     5641 cttatggttt catttgcaga ccatgcaaga gcctctcttt ttttatcggg aacagcagca
     5701 gattttccta ttcgattcca cctatatatt cagcatactt aagcagatag gggggctagc
     5761 gacttttatc tctcaattct tgatacagtt tttcagaatc ccgcttatcg gatcgctggt
     5821 gaccgccttg atcggtggaa tctccggttg gttattctgg ctgaccttac gaaagataca
     5881 tccggcatta tatcttatgc ccttggcctt tctccccatc ctattccaat atctttacct
     5941 aatgaaagat agctatcatt atgaaggact gatagccatg ttgttttggt cattggcgct
     6001 taacgtatat agttacagcg cacgaagatt taattggacg taccgtacct taattggttg
     6061 cttgctggcg accggattgt tttacacgat gggatctgta gctatattat tcgcccttag
     6121 catcttacta tttgatgtat tacaaaaatg cgaacgctgg tacgcaagct tcatcccgtt
     6181 gctgctgcta cttatcgtag gctccctatg tgtcctagga ggcagtaaac ccgattatga
     6241 ctatgtattt tggatgaaag attacgtaga gtatttcatt gagctggaac cattctacgg
     6301 cttctcttgg caagtagcgc tactcgttat gcttctattc ttcctatcac gttacttaga
     6361 tcacataaaa acctatttaa aagctttagt agccgtagca ttacttgcct tatccggtat
     6421 gtattatacg caaacggctc ttcaacagag gaataaagat ttctatacgt tgatgcaaat
     6481 gtttcattat atagataccg agcaatggga cgccataatc tcgtccaccg atctgaacta
     6541 taataactac ttacacctaa attgcttaaa ccttgcctta tcccataagg gtgtcatgca
     6601 gactgattta ttcaaatatc cgcaaagcgg aatacaatct ttggtctcaa agtaccaagc
     6661 gcatatagag gaaagtttcc tgttcagcca gatatactac catgtaggaa tcacgtcctt
     6721 ggcatacaat ttcgcttttg gtacctcggt aggaattaca tacggcagtc ccgtcatgac
     6781 taaattatta ataaaatccc atttgatata cggacagtat cccgcggccg agaagtttat
     6841 atccttattg gaaaagacat gggcctatca cgaatgggcc tcctcgcaac gaaagttctt
     6901 atataatgac caagcggtgg agagcgaccc ggaattaggt acaaaaagaa aaagtctatc
     6961 caacgacaaa gaccttttcg ccaatataat cggattgttt gataacctga tgattatatt
     7021 ggaaaagaat ccccagaata aagccgcact ggattatacg atcggtacgt tattattatc
     7081 gaaagacctg cccgctataa aaacgtttgt tgaaagattc agtgggacgg aagtactccc
     7141 cgcattaccc gaacccttgc aacaagccgt gatctcttat gcggagcatg atccggaata
     7201 ttgccgcaag tatggggtaa ccgataaaat cctgtccgag ttctcgatat tcaagcaacg
     7261 tgtattggga ctaaggcatg cccgacaaaa tgtagcgact ggaatagccg actatcaacc
     7321 tactttctgg tactatttga tactctctaa ataaaacaca tatggaaaga cagacttaca
     7381 caaatacaaa ccgatatctt ttcctttttc tcatcgcctt gatggtttca tgctccaaaa
     7441 gcgacataca gattgccaag agtctaaaca aggaaatcgc tatttatccg gattacaagg
     7501 atgttaccat ccctgtgaac atcgccccgc tcaatttctc tatcgccgat agcagtgagc
     7561 actgccttat cattaaaggg gaaaagactc aactccaagt ctatagcgat gaggggctct
     7621 ttgagatccc acaaaagaga tggaaagcct tattgaaaga gaatgccgga aaccaaatag
     7681 aattgaccat cgctaaacgc atacagggcg aatggaacgc ctatacgcct tttcatatgg
     7741 acatcgtaaa tgattccatt gataaatata tagcctatcg gttattagcc ttgagcaatg
     7801 atatgtggaa caggatgggt atctatcaac gaaacttgga aaattatgac caaagcgtga
     7861 tttatgagaa tagcctaacc gactataact gcgtaaactg ccacacgttt tcctccggga
     7921 acccggataa aatgattttc catatgcgag gcaaacacgc cggttccgta ctgattgatg
     7981 gaaagaaaat caccaagcta aatacaaaga ctcccgagac cgtctcaaac tttgtctaca
     8041 tgtattggca tccgaatggt aactatctgg cggccaccgt atgcgatacc taccaaaact
     8101 tcttcatcaa taatcccaat acgctggaag tattggatca taactccgat atcgtgatct
     8161 acgacgtgaa gaagaacgag gtattctctt gcgaagcgtt aaattccaaa gacgcatggc
     8221 aaatattccc agcgttctct cccgacggga agagcctcta tttcagttcg accgccgccg
     8281 tagattctat ttctaagaat ttcagacaaa tgacctacag tctatgccgt gtcgactttg
     8341 acccggaaac ccgcactcta ggccagcaag tagatacttt atacaatggc cgggccaacc
     8401 acaaaagcgt atccttccct agaatctcac cggatggtaa atatctggct tttaccctac
     8461 aggaatatgg cggtttcggg gtttggcata aagacgccga attatatatg atccgcctat
     8521 ccgacggaaa gacgtacccg ctaaccgagg cgaacagcgc cgaaggagaa agctaccatt
     8581 catggagcca caacaatcgt tggctggtat ttagcagtcg caggttggat ggattataca
     8641 cacgcccgtt ctttacctat atcgatgata aaggcacggc ccataaacca ttcctcctgc
     8701 cacaaagaaa tcccgtaaaa tattataaaa acctgttgtg gacttacaac ctcccggagt
     8761 ttatacaaga aaaggtccaa gtagacactc atgccgtgat ggaaacaatg agaaatacaa
     8821 aaggaatcca tgtaaaataa gaacaatagc tagggtgggt gaaaggagat aaggatgtct
     8881 gtttggttaa atctacccac ccttagctat tgatctgttt gctcactctt ttatcttcac
     8941 cgagaataga aatagagcgt ttcaaatcaa cgcccatatt tccatttgtt gtattcataa
     9001 aataagtaca aactttcggc aatcagattt cactctttgg tgaaacaaac atatgtaatc
     9061 tgcgtttata gattatcaaa tgtctcttta aaaacttgag acaaaaataa actattttga
     9121 tagaaaaata ggtctgtaaa tattcacatt ttattcacaa cacacaccaa aacgttcatt
     9181 tatcctagga agcatcacaa tttaacattt aactgctcca tcatcactcc ggtcttctcc
     9241 cttgcctccg tcacatccaa accacgagcc agcaagacgg ccatacggcg atgtccatga
     9301 acttccggtt ttccaaagaa acgcatctgc gtatcgggtt gttccaaaac cttatccaga
     9361 ttccccaaag acaaccggtc actgtcccct tccactacaa cggcacggga agctcccgct
     9421 ccatgaaaca cgatattagg gatcggcaag ccaagcactg cacgggcgtg caaagcgaat
     9481 tgagacaaat cctgtgtaat catcgtcacc attccggtat cgtgcggacg gggggaaacc
     9541 tcgctgaata tgacatcatc tcctttaatg aataattcca cgccgaaaat accacgtccg
     9601 cctaaagcct cggtgatctt accggcgatc tcacgggctt tcgctttagc ggcaaggctc
     9661 atggcttgcg gttgccaaga ctcccggtaa tcaccgtcca cctgaacatg tcctacgggt
     9721 tccaagaaag acgttcctcc gatatgccga accgtcagct gggtaatctc atagtcgaaa
     9781 tccacgaaac cttccacgat caccttaccc gctccagcac gtccgccttc ttgggcgtac
     9841 tgccaagcac gatcgatatc cttttcctca cgaaccacgc tctgtccgtg tccgctcgag
     9901 ctcatgatcg gcttcaccac gcaaggcata ccgattacct tcaccgcttc cttaaattcc
     9961 tcctcggtct cggcgaaacg atacggcgag gtaggcaagc ccagctcctc ggccgccaag
    10021 cggcggattc cctcacggtt catcgtcagc caagtggcac gggcggtagg aatcacatgg
    10081 tatccctctt cctccagttc catcaaagta cgggtagcga tcgcttccac ctccggcacg
    10141 atataatccg gtttctcttt ctcgatgatc tcccgcaagg catcgccatc cagcatggag
    10201 accacatagg aacgatgcgc cacttgcatg gccggagcgt ccggatactt atccaaggcg
    10261 attacctcca cgccataacg ctgcaactct attacaaact ctttccccaa ttcgcccgag
    10321 ccacaaagca cgactttagt tgccgtagcc gatttgggcg taccaattgt taccataaat
    10381 ctttctgcta tttgaatttc gccgcaaagt taagggttta tgcctgtata gcctaaagct
    10441 tttcccttta tctattaggg caaagataag gttagcttca tcgtccaacg gctggtggac
    10501 gatcatgcac cagttggtag atgatcatgc accagccgtt agaagatcat gcatcagttg
    10561 gtgcatgatg aatgtatcct tatgaattgg gtaagacagc cgcttgttta gcctaaaata
    10621 tacagaggaa aggaacaagg atctacttat aatcaagacc tctttgttaa tattacataa
    10681 ttagtagtac cttgcgatac aaggtatctt agtaaaacat atatttgtaa ccagatgata
    10741 aaagtgttca ccaacagtgt aacttattta gcaaactgta cgtctaatat ataaagtaac
    10801 tacataatat gatgattcaa ctgaaaggaa taaacaaaac gtactttaac ggagccccac
    10861 tgcacgtttt gaaaggtatc gacctagata tagagaaggg agagatggta tctatcatgg
    10921 gagcgtccgg ttccgggaag tcaaccctat tgaatatctt ggggatattg gatacgtacg
    10981 acacgggcac ctatctatta aacggacagt tgattcagaa tctaagcgaa agccgtgccg
    11041 ccgagctgag gaaccgtatg atcggcttca tcttccaatc atttaactta atctcgttta
    11101 agaacgcagt ggagaacgta gctctcccac tctattacca aggcgtaagc cggaagaaga
    11161 gaaacgccat ggcactggaa tatctcgaca tggtgggatt gaaggattgg gcggatcata
    11221 tgccgaacga gatgtccggc ggacagaagc aacgtgtggc catcgcacgt gccttgatcg
    11281 ccaagccgca gattatattg gccgacgagc ctaccggggc attggatagt accacgaccg
    11341 tggaagtgat ggaactcctc cgtagcgtaa accaagaagg tatgaccatg gtgatcgtta
    11401 cccacgagcc atccgtggcg gaagctaccg accggattat ccgggtaaaa gacggattga
    11461 ttgaatacac cgtaaacgaa gaatcgcatg tttgattttg acaattttag ggaaatatgg
    11521 agcacgataa agaaaaacaa gctccgtacc ttcttgaccg gtttcgccgt atcatggggg
    11581 atctttatgc tgattaccct gttgggagcg ggaaatggat tgagaaacgg catcatattc
    11641 aacttccgga ggttttccgc caataccgtg gaggtttggg ggcgctatac caccatgcct
    11701 tataaaggta accccacgaa ccgcaggatc gagttcaagg aagcggatct cagcggcatc
    11761 aagatggcat tcccggaaat agaatactgc tcggctacca tttcgcaaac agataccatc
    11821 tcgtatgggg aagaatacat cgtgggcgac ctgcggggcg tatccgagga ttacaattcc
    11881 attatatata ttaatgtagc gagccagaac gggcgcttca tcaataagat ggatatgaac
    11941 gctacacgca aggtaatcat actaagcccc cgtatggcgg aagtgctatt ccgtaacgag
    12001 gacccgctgg gtaaatacgt gaaatgcggc aatatgatgt atcaagttgt tggtatctat
    12061 gatgatgacg acaagagtaa caacgcaccc gcatatatac cgtttaccgt agcgcaacaa
    12121 ctttataata aaggcttcgg gttcggctcc atttacttta cggtaaacgg ggtctccacc
    12181 gaagaagagt gcaaggattt cgagaacagg ttccggtcgt atatggcccg taagcacata
    12241 ttcgacccga cagacaagaa tgccatcggt atgtggatga ccggcaatga gatccgtatg
    12301 ttcaatacga tgacagacgg tatcttgctc ttcatctgga tcgtaggtat cggcaccttg
    12361 atggctggta tcgtgggggt tagcaacatc atgttgatca ccgtacgcga acggacccgg
    12421 gagttcggca tccggaaggc gatcggggcg aaaccggcct cgatattgaa gcttgtcatc
    12481 gtagagtcca tcatgatcac cgccatattc ggttacatcg ggatgctgat gggaatcggg
    12541 ttgacggagc taatcgacta tggcatgacg atgagcggga tgaacaacgc ttcatccgga
    12601 ggaaatcccg gcgaggatct taccttattc cggcacccga ccgtcagcct agggatatcg
    12661 ctggccgcta ccggggtgct ggtcgtagct ggggtgctgg cgggctattt ccccgctcgc
    12721 aaagccgtga atgtatccgc tattgaagcc atgagaacag aataaaccga aaagatatgt
    12781 ttgacataga cagatggaca gaaatatggg taaccatcac ccgcaacaag acacgtagct
    12841 tgatgacttg cttcggcgtg ttctggggaa tccttatgct ggtattgttg ctgggtaccg
    12901 gatcgggatt caagaacgcc atgttcaaga gcgtcaacgg attcgcgacg aattcgctat
    12961 tcttctacgc cgatcgcacc agcgaaccct accaaggatt caacaagggg cgaaactgga
    13021 acatgaggaa ccgggacata gacgccatca tacgagacgt acctagcgta caggatatct
    13081 cccccatcct ttggggcagc cgctcggaaa agaatatcgt ttacgggata atgaccggaa
    13141 cgttcaacgt gaaaggtata tatccggctt acttcaatat cgatacgcaa gacctatact
    13201 atggccgttt attgaatgag atcgatatgc gggaaaagcg caaggtttgc ttgatcggca
    13261 cgaagatcaa tgaggtatta ttccacaacg aggacccttg cggcaaatat atccgggtga
    13321 acgggcttta ctaccaagta gtaggagtgg tcaaccaaag ggcatcgggc ctgaatctgg
    13381 gcggccgggg agaagaaacc gtcttcattc cgttcaatac catgcagcag accttgaacc
    13441 aaggcgatat cctgcatttc ctcgcactga gcgtgaaacc gggatatccg attgagacga
    13501 cgatcgagca ggtcaagaat atcatgaaga cgcaaaatca gatcgcaccg accgatcctc
    13561 aggcgatagg cgtagtcaat atcgccgcac aattcaagac attcaatcta ctgtttacag
    13621 gtatcgacat cttggtctgg ctggtcggca tgggtacctt gctatcgggt attattggta
    13681 tcagcaatat catgatggta acggtaaaag agcgcacgag ggagataggc gtacgaaggg
    13741 ctttgggagc caagcctttc gacatcatct cgcaagtcat gagcgagagt ttggtgctga
    13801 ctgccttggc gggcttactg ggattaagcg ccggagtctt cctcttggat ttgttggata
    13861 agatattgtc cgccaatcca acgaacgatc cgaccctgct gaatcccggc gtaaacatcc
    13921 aaacagcggt agccgccgcg gtggtactac tgataagcgg ttttatggcc ggactgattc
    13981 ccgcatggag agccatgcag atcaaagcga tagatgccat ccgagatgaa taataacgaa
    14041 tcgataatta aaataaaact atataatcat gaagaatcgc atcgtaaaga aaatcctacg
    14101 tattatctta ttaacgatcg taggtgcggc ggtaataggc acattctatt tcttatggaa
    14161 gaaggcgcaa ccggtaataa ccgtttatga ggtcgtaacc cccaaaaggg atacggtaga
    14221 gaccaagacg gtggccaccg gaagcgtgga acctcgctac gaggtagaga tcaagccgca
    14281 gatatccggt atcatctccg agctaaggaa agaagcggga cagatggtac aggccgggga
    14341 gattatcgcc acgatcaagg tcataccgga gatggtacag ctaaatagcg ccgaatctcg
    14401 cgtaaacata gcggatatat ctcttaaaca ggtggaggaa acctataaga gagatgaact
    14461 gctgttcaag caaggtgtta tcgcccaaga ggatttcgat ctctcgaagg ccaactactt
    14521 aaaggcggtc gaggagaaag agaatgcgca aagcgcactg gaaattattc gtgacggtat
    14581 cgccaagaac tccaatgtag ccagtaccac gcagatccgt agtaccatca ccggtatgat
    14641 actggatatc ccggtgaaag taggtaactc cgttatccaa gcgaacaact tcaacgacgg
    14701 tacgacaatc gccacagtcg ccaacatgaa tgacatgatc ttcaagggaa acgtagacga
    14761 gaccgagatc gggcgcattc acgagggaat gcctatcaag cttacgatcg gagccatgga
    14821 aagccgttcg ttcgaggcct tgctggaata tgtatcaccc aaaggtgttg agaaaaacgg
    14881 agccattcaa tttgagatca aggcagccgt gacgatcccc gaagatgctt tcatccgtgc
    14941 gggatatagc gccaacgccg agatcgtgct aaaacgtgcg gaagacgttc ttacgatccc
    15001 ggaaagcacg gtcgagttcc aaggggattc cgcattcgtt cagttagtta aacaagagca
    15061 accggagcaa gtcttcgaga aacatccggt aaaggtaggt ctgtccgacg gtatcaagat
    15121 cgaggttcaa gaaggactgg ccgcgaccga taaagtccgg ggcgcagcta ttgacccgaa
    15181 taagaaataa aagaaagatt gtatgatgag aagaaactta tatatactgg caatcgcttc
    15241 cctcctgtcc ggaaactatg ttttcgctca ggatgcggtg aagcaatgga gtctggagga
    15301 gtgcatccaa tatgccatcg agcataatat cgacttaaag caaaaggagc aggaacagga
    15361 aagccgaaag gtagacttac ataccagcaa atacagttgg ctcccggccc taaacggcag
    15421 tcttggacag agcttccagt tcggacgctc cacgtctaaa tccggggtga tcgtggacca
    15481 gaacgccgcc aattccacat tggggatcaa tctggacatg cctttatttg acgggttaaa
    15541 aataccgaac gatatcgccg cccgcaaact tgatctaaaa gcgtctatcg agaacttgaa
    15601 taaggcgaga gaagacctat ccatcaatat agcttcctac tacctgcaag tactttataa
    15661 taaagagtta ctgaaaatag cgcaactaca agtggaacta gacaaggagc aggtgaataa
    15721 aacggaggcc atggtgaacg ccggaaaggt gccactttcc caactgtatg atatcaaggc
    15781 ccaattagcg aaagatgagg tcacgcttac cgagtcgcaa aacaatgtga acctcgcttt
    15841 actggatctg gcgcaaagtc tggaactaga gcgaagcgat cggagtttcg atatacagac
    15901 tcctgtaatt gaagatgcgg tggctgataa tatgagtagc atcctacctc cggaaaacat
    15961 ttacgatcat gcggttacgt tcaagcctca gatcaaggaa caacagtatt tgctagagag
    16021 ccaaaagaaa atgttgcgtg tcgcgcaagc gggctattac cccaagttaa atttcggggc
    16081 tagttacagc aatggatatt atcattctac ttccggaggt gaatttgccg atactcgttc
    16141 ctttagcgag cagtttaagc agaatgggca aaagatcgtc ggattctcat tgagtattcc
    16201 acttttcaac cgcttccaag tacgcaatag cgttcgtacc gcaaggatca acattatcaa
    16261 ccgggaattg ctgatggaaa atacaaagaa aacgttatac aaggaaatcc agcaagcgta
    16321 ctacaacgca acggcttccc aagagaaata tacggcttcc gacaaatccg tcacggcgag
    16381 caaggaagcg ttcaattatg cccaagagcg ttacaacgca ggtaaaagca ctgtctttga
    16441 atttaatgag gctaaaacaa aatacgcgca aagtctagcg gaacaggcac aggccaaata
    16501 tgattttatc ttccgtacga agattctaga tttctataat ggtaacccta tccgtttata
    16561 aacgttaatc aatactttat ttttttatta tacacacaaa gtttaaggga agatatcctt
    16621 tatggacatc ttccctttca gcatccatta aggcatttag tctgcacaga actacagtta
    16681 aaatacttat caaaaaaatg tacacaccaa gactcctgaa aatcacagcc gcaaatatac
    16741 taatttttat tataaaaaag caaactgtta taaaacattc taaaactaat ataatattga
    16801 ttgatattgt caaattcaat ttagttgtac tggggatctt gttgcattat gatagctggc
    16861 aggagggttt ttagtcttag ctatctatct gttaattatg ctgttaaata tagttctgtg
    16921 caaactatgg tctcttgaaa aaacaatgtg tgtctaatta acaaacaaat tcattctatg
    16981 aagcacaaat taacgcttgt actactctca ttctttctgg gagtgcagtg tatggtcgcc
    17041 cagcaaatga aggtgaccgg tgtagtgatt aatgaagatg atggggagcc tgttataggt
    17101 gcatccatcg tagtaaaagg aaccactatt ggaaccatta ccgatttaga tggtaaattt
    17161 gagttagaaa ctcagaaaga tgctaagcta attatttctt atgtaggttt acggactcaa
    17221 gaaactacag ctcagcaaaa catgagaatt gttctttctt cagattctca agctatagat
    17281 gaagttgttg tcgtagctta tggtaccgca aagaaaagtt cttttacagg ttccgcatcc
    17341 acggtgggtg ccgctttgat ggacaaacgt ccattgagta acgccctctc cgcattggaa
    17401 ggaaacactt ccggagtaca aatgacttcc tctatcggac aaccgggaga agctgccaag
    17461 gtaacgatcc gtggttttgg ttcagtaaac gcggataatg ctcctttata tgtagtggat
    17521 ggtgccatct tcagtggtga tatctcttct atcagcccat ctgatatcga atcaatgaca
    17581 attttaaaag atgccgcttc tacatctttg tatggatcta gcgcaggtaa cggtgtggtt
    17641 ttgatcacga ctaagaaagg ttctagcagc agtggcgcag gtgttacctt gagtatctca
    17701 caaggttggt ctagcagagc ttataacgat tacgcaaaag taggtgtata cgattattat
    17761 cctttgcaat ggcaaatgtt gagaaacgca aatatgtcac tcggacaaag tgctaccgac
    17821 gctgccgcta atgcttctaa agatattatc aacaaattaa aatataatcc tttcgtagga
    17881 atcgccaatg acgcaatcgt gggcacagac ggtttattga atccatcagc ctcggcttta
    17941 aaatggggtg aggaccttga ttgggaagat gccgcttacc gtaccggaca tcgccaagaa
    18001 tataatgtaa gctacaatac aaaaacagaa aagagcgaca catatgcttc cataggctat
    18061 ctgaatgata agggatatat gattaagaca gactttgagc gttacaacgc acgcttgaac
    18121 tataatatct atccggtgaa atggttcaag agtggattga atttaggttt aagtcgtaca
    18181 aactccaatt attctacttc tacttctagc aactccgctg gttatggtaa cttatctcgt
    18241 ttcattcgtt ctatggcacc gatctatccg gtacataagc atgatattga gacaggggct
    18301 tatttggata aagaaggaaa cgtagttact gatccggctt tatataccta cgattatgaa
    18361 ggagcccgta tctccagcaa tggacgcgac ggtatcgctg aggccctgtg gaacgatcgc
    18421 ttgatgtcta ccacaaactc tagtgcccgt acttatgtaa cgatcactcc gatcgaagga
    18481 ttgaatttaa cagtgaacta cgcatttgac aataaggatg aacgccgtag agtatatgag
    18541 aacccagagg taggtgacgg aaccgcagga ccgggacgtt tgaacatccg aaatagaaac
    18601 ttcttgacac agacattcaa ccagttgatt aattacacaa agacttttgg taagcataac
    18661 atcgaagctt tgttaggcca tgagaactat agctaccgtt tacaatataa ctacggtatg
    18721 aagactaatg agatcgtttc cggaacgtat gagtacagta acttcgtaag cataagctca
    18781 atggattctt atacacgcga atataagaaa gaaggatact tcgctcgttt gaactatgat
    18841 ttcgatgata aatattatgt aacagcctcg tatcgtcgtg acggttcctc tcgctttagc
    18901 aaggataacc gttggggtaa cttctggtca ttcggagcat cttggcgtat cagccaagaa
    18961 gatttcatgg aaaacttgac ttgggtggac aatttgaaac tgagggcatc ctacggtgaa
    19021 accggaaacg atgccatcta ttatacagat gatgacacac aacaggatta ctatccttat
    19081 caaaccttgt ataatttggg tatcaacaac ggtttggaag caggtctcta cttcccgact
    19141 atggcaaaca ataatttgaa atgggagaca caggtttcta ccgatgtcgc tttagaattc
    19201 ggattgttcg gtcgcttgaa tggtacggtc gagttcttcc gtaaggcctc cagagacttg
    19261 ttattcaatg ttagccaacc gttatccagt ggtgtcgaaa agatcgtaca aaacattggt
    19321 aaagttcgta accaaggggt ggaaatcgac ttaaactacc aagtattaaa atcaaaagat
    19381 tggaaattat cagtcggcgc aaacgctaca ttcatcaata ataaggtgac tcgtctgcct
    19441 gatgccaacc ggaaagatgg tatcatcaaa gactctaaga aattgatgga gggacattca
    19501 atctatgagt tctggttacg tcaatggtgg ggtgttaatc ctgataacgg agatggattg
    19561 tatatctttg atgccgaaaa caacaccgat gcgaatggta atattaaaga tgcggtaaaa
    19621 aagacacttg tagagaaaga tggtcaagta ttgacaaact cttatagcta tgcgaaatat
    19681 gatttcagtg gttctgccgt tccgaaagta tatggtggtt tcaatatcaa tttgagctat
    19741 aaggcattcg acctttctac cgtattctct tattcattag gaggcaaggt gcttgactcg
    19801 agttatagag gattgatgga tgtaggtgag ttcggttatg cgatgtcacc ggatctacat
    19861 aacgcatgga caactccggg ccagatcaca gatgtacctc gtttggacaa taactcaggt
    19921 catgcgacta gcattggaca atcctattct acacgttggt tgacaaacgc aaattacttg
    19981 aacttgcgta ctgtcacttt ggcttacaac ttgcctaagt ctatcctaaa cgttatcaac
    20041 atcaagagtg cacgcgtcaa tgtcagcgca gagaacttat tcatgttgaa agcccgtcaa
    20101 ggtctgaatc cgcaagctaa ctatgccgga gtatcttaca atgaatatat gccggctaag
    20161 aactttacga tcggtttaaa tgtatcgttc taaattcata atacatcaaa caaaggaaaa
    20221 gatatgaaaa atatacaatt attcaaacac atcgcagcag gactgcttct aagtggctct
    20281 ctgatcggca caagctgttc cagcgattat atggatacaa tcccaaccga gaacgtttca
    20341 ttcacgacag tatccacttc gctcgacaat ctttatcttg cactgaacgg tattcatcgt
    20401 aagatggtat ctcaagactt aggcaaccaa ggtttgggag gtgagcccgg tttcatcatc
    20461 ggtcgagaag cgttagctga tgatttgaca tgggacacgc agacttggca tcaaggtttc
    20521 ttaaactgga gttatccaac gaacgcaaca agttcgtaca actccggtga gtgggaaact
    20581 tattataagt tcattttgaa tgcaaacaac atcttgaaag cgttgaatga taactttagc
    20641 gatgagtcaa aactcacaga tagcgaaaaa gcgcttgcga accatatcaa gggcgagtgt
    20701 ttggcaattc gtgcatggag tcatttcaat ctagtacaat attatgcgaa accatatcgt
    20761 aacggacagg acaactctca accgggagtt ccttatcgta cgagtccgga aatcgagcct
    20821 atggcacgta atacggtaga agaggtgtac acaaagattc acggggactt agacgaagca
    20881 ttgaacttat tggcagacta tgagccaaat gataagaatc attatagcct agcatcggtt
    20941 tacggattga aagcacgtgc tcttctgact caacagaaat acgcagacgc agctacggcc
    21001 gcagtgaatt ctatcaatga agcagagaaa gatggctgta agatcatgtc tcagtctgaa
    21061 ttgatgaatg gtttcgctaa tatcacttcc gctacgaaag aggcgatgta tgccgcaatg
    21121 acacagaatg accaaacggt ttatttctac tctttctatg cgtatatgtc ttggaacttc
    21181 aactccagct ctatccgcac aggtatcaaa tgtatcagcc aaagtactta cgacttaatg
    21241 tcgccaaccg atcttcgccg tcaatggtgg gatccgacag gaaaggcaga agtacccgca
    21301 acttcttaca accagcgtgt ttatcagaac cgcaagttca cggcacgctc tacagctgat
    21361 gctgtaggtg attttgcctt catgcgtatc agcgaaatgt atttgactgc agccgaggct
    21421 ttcgctcgtt ccaatcaaga cgcaaaagca aaggaatatt tgcaagcctt gttgaaagaa
    21481 cgtgatccag agtacaagga tttgggtaac acaggcgcaa aactagcgga tgagatcatg
    21541 acacatcgcc gtatcgaact ttggggcgaa ggtttccgtt ggttcgactt gaaacgtcta
    21601 ggtttgccat tggatagaac cgggtctaat tttgacgcta ctttctgtgg tttcttgcac
    21661 aaggatccga atgctgatgg ttggatcttc gagattccaa aaaaggaaac agatttcaac
    21721 gacttgatcg aaaagaacta ttaacactct ttttacgtta acttacatta atcacaatcc
    21781 ccaaagtata ctttaacagg ttatctttgg ggatttctta tatcactatt tatgaaaaca
    21841 aatcatttat tttcagctct gctctcttta gcgcttatat gtcctggaat agcgcaagaa
    21901 acacattatc aacgtcctcc agccgtaata gaggaagtgg ccctagccaa attatccccg
    21961 atcatccgaa ttagtgataa caatcagtgg gcactccagt tagagcgttc cccgtaccgg
    22021 tctatcgcca agcttgcgca accggagctt aaattagcgg gaatgcgtat cagtcccgaa
    22081 acattcaata cgagccggca agccgaatat acgggtgcca gtttaatgaa catcgctact
    22141 caagaagaaa tcaagattga aggaattcct gacaacgcgg taatcacaga agcctcattc
    22201 tctccttcat ccaataaggt agctctattc gtggaagaag cgaatggcgt atatctttat
    22261 aactgtaccc cggaacagcc cgtagctcag aaagtaagta cccgtaaaat caatgcgaca
    22321 agtggagcgg agatcttatg gattagcgac aatgagttta ttacgcttat ggttccagaa
    22381 aacaggggaa aggcaccgga gaaacccaca gtcccatccg gtcccatcat tcaagaaagt
    22441 actggaaagg tgatgcccgc tcgtacctat caagacttgc tgaaaaatcc gtacgacgag
    22501 caattattcg actattactt cacctcccaa ttggtacgta taaaagaggg cattgtgtac
    22561 gagatcggaa aaccggcaat ctacggcagt acgctttcat tatccccgga taaatctttg
    22621 ctacttatcg cgacagttca tcgtccgtat tcctatcaag taccggtata taacttccca
    22681 caaaagttcg aggtcataga cttacaaggc aattccattt atacgttagc ggataatcca
    22741 accgtcaata ttccgatggg atatgacacg acctcgcctt atccccgtca attcggatgg
    22801 agatcggatc aaccggctac cgtttactgg gcggaagcgc aagataaagg agatcctaag
    22861 caaaacaaga ccgatttcat ggatattatc taccaaataa gctatccgtt caacagcgag
    22921 aaacaggaag tcgcaaagac agagaaacgt ttccgcaaca tcctgtggaa tgacgatgct
    22981 ttcgctttat tgatcgagac ttcccgggag actcgtaaaa acaggacatt tacttttaag
    23041 ccttgctctt ctgagtctcc ggttctatta ttcgatgtat ccaccgacga taattacaac
    23101 aatccgggaa atccacttac gattaaaaat gcgtatggta aatatatcgt ttataccaat
    23161 aaagcccaca atgagttatt gatgcttgcc caaggagcct catctaaagg ggatatgcct
    23221 taccttagcc gttacaattt gaaaacaaaa aagaacacgg aactttggcg ctgcgaggac
    23281 ggatattatg agaccatcct aaaggtagcg aatccggaaa agcttcaatt gatcacttca
    23341 cgtcaatcca ttacagaacc agcgaatctc tgctctcgtg acttgaaaaa gaaaaaattc
    23401 gctcaattga ctcatttcgc caatccatat ccggccatgg caaacgttag caaacaaaag
    23461 atcaagtata aacgtgcgga tggtttggat ctaacagcga ccgtatacct ccctgccgga
    23521 tatgataaag cgaaggacgg tccattacct gtcttaatgt gggcctatcc gagagaatat
    23581 aaaagcaagg ccgaggcttc tcaggtacga ggttctcaat acatgtttac gaatatcaac
    23641 tatggttctc ccgtctattg ggttttacgt ggattctgta taatggaaaa tgtcgagatg
    23701 ccgatcgtta gtaccagtga gggagcggag ccgaacgatg atttcattga gcaattgaca
    23761 atgaacgccg aggcggccgt aaaagttatt tccgagatgg gtgtaggtga tccgaatcgt
    23821 gtagccgtag gaggacattc ctatggagct ttcatgacag cgaatctatt aacacatacc
    23881 aaactgttca aagccggcat cgcacgtagc ggagcttaca accgtacgct taccccgttc
    23941 ggcttccaaa cagagacccg tacttattgg gaagtaccgg aaatatataa tgccatgtcg
    24001 ccattcatgt ctgccgataa actacatgga gctttattaa tcatacatgg tgagatggat
    24061 aacaactccg gaacctttcc gatccaatcc gagcgcctgt tcagtgccct aaaaggccac
    24121 ggggcgatcg cacgttatgt cgtattgccc tatgagagtc atggctacgc cgccaaagag
    24181 aacatattac atctattgta tgaatgtgac ctatggctgg atcgttacgt caagaacgca
    24241 aaaaagtaag tagtactgac tttgtcaatg aagtatatat cctctgacag gaaaagtata
    24301 tttcctctaa ccagtgaagt atatcttcta tgaggaagcc agccggcagc caccaattgc
    24361 cctaaaacaa cgatgcccat cgtaaggtta taagaatgcc catcgtaaac tccttacaat
    24421 gggcattctt aactccttac gatgggcatt caaagaaagc cctatctgag attcgtttat
    24481 ttcagcagtg agcaaggaca aagatgatcc ttctcgatat ccttgaaata gttataagta
    24541 cctaccttaa gatccgcgca agccgcctca tcgcaaacga tgattccttt cggatgcaac
    24601 tgcaaggcgg taattgtcca catttggttc acggcaccct caacagcttg ttgcaacgca
    24661 cgagccttgt tatgaccatt taccatgatc aatacctcct tagcgtcaag aaccgtacct
    24721 acaccaaccg ttacagaagt ctttggaact ttattcacgt cattatcaaa gaaacgggag
    24781 ttagcgataa tcgtatccgt agttaacgtc ttgatacgag tacgagaact caaagatgaa
    24841 cccggctcat tgaacgcaat atggccatca ggaccgatac cacccaagaa caggtctacg
    24901 ccaccgaccg ctttcatgcg agcctcataa gacgcacact cagcctccaa atcctcggcg
    24961 ttaccattca agatatttac gttctccggt ttgatatcga tatgactgaa gaaattattc
    25021 cacatgaaag aatgatagct ttccggatga tctttcggaa gaccgacata ttcatccata
    25081 ttgaaagtga tcacattctg gaacgataca actccctgct tgttcaattc aatcaagttc
    25141 ttgtacatac ccagcggaga agatccggta ggcaagccca gtacgaatgg tttttcagcg
    25201 gttggattcg cggctttgat cttcgctgct acataattgg cagcccattt tgagagttgc
    25261 tcgtaattag gttcgataat tannnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    25321 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    25381 nntacgaatg gtttttcagc ggttggattc gcggctttga tcttcgctgc tacataattg
    25441 gcagcccatt ttgagagttg ctcgtaatta ggttcgataa ttagtctcat aacgttatgt
    25501 tttttaattg aaagttgtat caactttctt gtttataaat tagatttgtc gttaattgtt
    25561 ttcaatttcc cagccatttc cttgcccaaa gctaaacact cctcgtattt agtagcgctt
    25621 aaaccttgct tctgctcaac cggcgtaccg acagtctccc acttcatctt ctcgccaaaa
    25681 gccgccaaac gtttcacggc ggctccagcc catgtgaaag acccgaaata accgaaaata
    25741 cgatttttca cctcacgcaa ctcgatctta ctcaacacag cttccacctc tgggaacaat
    25801 tgattgctat aagtcgggct acctacgata actcccttat atttgaacac atctttcaag
    25861 atataagaag aagggctttt gctaacatta tgcatcacga tattcttaat gccattatca
    25921 gccaaagaag cggcgatcgc ctcagccatc tgctccgtgt taccatacat gctgccataa
    25981 ataataacca cgccttcctc accttcgtag cggctcatac ggtcatagat atcgatcgct
    26041 ttcgacgcat attcacgcca aacaggtcca tgggtagagc aaatcgtctg gatatccaag
    26101 cccgaaagct tctgtaatgc cctttgtact ggacttccat attttccgac aatgttggag
    26161 taatagcgaa tcatctcttc ccaataatgc tccacattca tctccgtatc gatcacacca
    26221 ccatccaatg tgccatacgt accgaacgca tccgcagaga atacgatttt atccgtaacg
    26281 tcataagtaa ccatcacttc cggccaatgc accatcggag ccatataaaa tacaagctca
    26341 tgacgacccg tattcaaggt atcaccctct ttcacctcaa acaagccttc cttgatgcca
    26401 tgatatcctt ccagcattcc gaaagtctta ttgtttccga caatctgtac gtccggatat
    26461 tgctgacgca acaaacggat acttcccgca tgatccggct ccatatgatt taccacgaga
    26521 taatccaaag aacgtccgtc caaggcatcc gctacttttt tcaagaaaat atcagagtaa
    26581 caaacatcga ccgtatcgat caatacggtt ttctcgtcta cgatcaagta cgagttatag
    26641 gaaacgccgt atggcaacgg ccacatattc tcgaagaggg ccttttgacg gtcattaact
    26701 cctacataat aaactttatc cgcaatttct tttaacttgt acatcttttt taattgataa
    26761 ttgataattg aaaattgata atcacgaagc gtgtgctctc taatcttcaa ttttcaatct
    26821 ttaattttcc atttcttagt gctctccaga caaaccagca ccctgccaaa acaaacggga
    26881 tacttagcca ttgccccata ttcaacatca ttccagcctc gaaaggctct tggtcatttt
    26941 tcacgaattc tatgaagaaa cgagacccga atacgcatat cataaatacg ccgaagataa
    27001 gtccttgctt tttccaagcc tctttcttga aatatagcca catacagata gcgaacgtca
    27061 ccagataaca agcggcctca tacaattgcg tcggatggct cggagcggta aaaataggct
    27121 ccgcccccat tctccatgcg tgtaaattat cgataaaacg aaatccccaa ggcaaatcag
    27181 tggaatgacc gtaaatctca tgattcatca ggtttcccag acgaatcata gcagctacca
    27241 atcctgtcgg aaccaccaac ttatcgaaag cccataacat acttttatgg cttactcgct
    27301 tcgagtagaa ataaatggcg ataattatac ctaacgtacc accatggcta gccaaacctc
    27361 cctcccaaat cttgaaaatc tcaatcgggt tggctaaata atattccggc gcataaaaca
    27421 aacaatgccc caaacgggca ccaatcaccg taccgagcat cgtataaatc aaaagggaat
    27481 cgatccatgc gggcggcagt ccctcttttt tccacatccg ctctacaatc atatagccaa
    27541 tagcgaaacc aatcgcgaaa gccaatccat accaacgaat ctcccgggaa ccgatggtaa
    27601 agatagcggg atcggcagtc catgtaataa aatcaagcat aattatttca gttggcaatt
    27661 gacaattgac agtcgacaat cgcaagtcag gatttcccga actgtcaatt gcctgctgtc
    27721 aaccatcaac ttatattaaa cgagtcttct aattaagttc tctctctcgc cgtacagcat
    27781 atcgattatc ggcaattcga tcatcgtata tgcgcccggt tgttgcttca agctcgcacg
    27841 agcgacagaa accaagattt gagcggtcaa ggcagggtta ttgatcttca tatcgaattc
    27901 gatcaactgg ttctgagtct tgcccgatac acctttacga accaagttca caccatgtcc
    27961 catgtccaac aaattatcga cacattcaac ctgcattaca tgagtctcat catgagcgaa
    28021 ataatcatcc gccttgatag cggcagacac ttgcttgaaa tcgtatccgt cttccacctc
    28081 gatataaacc atacgacggt gtacacctgt tcccaaagga atcgtcatac ttaaagccgc
    28141 tttcacgcct tcgatagcct tcacggcaac cgtatgcccc atactcattc ccggaccgaa
    28201 gttcgtataa gtaatacctt tcggcaccat cgcttctaac aaagcacgta ccactgagtc
    28261 gcttcccgga tcccaaccag cagaaattac agctaccgta ttatgagcct tcgctacagc
    28321 gtccaaagaa cgacgtaaat ccacgatacc tccgtggata tcgaaactat cgaccgtatt
    28381 gatgcctaat gccagaatct ctttcgcatg ctcttccacg ctgcgtgtag gagtagccaa
    28441 aaccgctacg tcaaccttat ctaacttggt gatgctatca gtaaccgtgt atgccttcaa
    28501 ctcgtccgga atatcattcg gattacgacg aataatacct gctacctcaa aatccggggc
    28561 agcttcaagg gcctctaaca catatttccc gatgttgcca taacctacga tggcggctct
    28621 aattttcttc atactctagt ttttactttt caaccaaccg caaagttaga tataatttag
    28681 agctttaaca ataaggaata cagtttttat atcattttca gaatgatata gatcctcact
    28741 ctttcacgaa tgaatccgga taggtagtaa gctgctctac accggctttc gtacgaatcc
    28801 aagtcttgaa ggtacgggct ccctcgttca actcgatcac acgtgctcca tttggtatat
    28861 ggatgtattc cgtcggacca cccgtaaaac gaccgtaagc caataatacg tcataccagc
    28921 aaaccgcata atcatcgtca tgatcatggc cgacaaatac gcccatcacg tccccgtttt
    28981 ccttaatcgc cgtaaataag ccggaattca aggccggagc gcatgccttt tccctacgta
    29041 tgccatagag ttgggcattc tcatcggaag ccgcttgatt aaactccggc aacgcaatat
    29101 ggaagaaagc caaagaagga accggctctc ccccgttatt ccgggtaaac tctgcgcttt
    29161 tcttacaata ccaatcgatc tggtcacgct taatataatc gtatcctttt acccccttga
    29221 tagttgaata ggtattcgaa tcgatgcaat acaagacgaa agcatccttc ttcccgtcgg
    29281 aggaacgtac ggtcaaggcg taattaccca cgcctgagat ttcgggaacc tcatccgccg
    29341 ttaaactata cggtaggctt tcggctactt tcagcaactc ctcttttgtc gccccctgct
    29401 cattatcatg atttccgaaa acaatggaga atggtatttt acggtcggag actgtcttca
    29461 atacattccg catattttcc aacgcaggct tgctatagat aatatctccc gtaaaaatca
    29521 ccaagtccgg tttctcgtca tccaacactt ggttcatacg ctcaaaagcg atgtccgaac
    29581 gagggtcttg ccatttcaca tgcaagtccg taaactgtac aatcttaaac ttcttatccg
    29641 gattaaactt caaccccggt ttttgggcaa atcccaaaga actcaagccg gcggccaata
    29701 acaaggcccc ggcaaacatc cactttctca cactcatcaa atctcgtgtt ttttgtaatt
    29761 aataattatt tattcctttc cgaaacaagc gtcgaacgca tgggcggaag gttggaaatc
    29821 cactctcttc accaattcgc aagattcccg tgccccatgt tcccgatcca tagcgctatc
    29881 ttcccattcc acggaaagcg gaccttgata gccaattgaa ttcaaagcac ggataatctc
    29941 ctcaaaatta atctttcctc gtcctaagct acggaaattc caatatcgac ggggatcgcc
    30001 gaaagtaaca tgaccgccga atatacccac ctgcttaggg gtatcactcc aatatacgtc
    30061 cttcatatgc acatggaaga tacgctccgg aaactgatag atgaaatcca catagtccac
    30121 cccttgatat cctagatgac tcggatcata gttaaaaccg aaagcaggat ggttatttac
    30181 cgcctccaat gccctgcgtg cggaaaaagt atcgaacgcg atctctgtag gatgtacctc
    30241 caacgcaaaa cgtacaccca gtttctgaaa ctcatccaag atgggcgtaa agcgacgggc
    30301 gaaatcatca tacccctttt gtatcatagc gtccgttacc ggagggaaag aatacaaata
    30361 atgccaaata gaactacccg taaaacctac aaccgtatcg actcccaaca tctttgccgc
    30421 atgggcggtc cggatcatct cctcggtagc ccgttggtga accccttccg gatcgccatc
    30481 tccccaaatg taatccggca agattgcctt atgacgctca tcgatattat cgcaaacagc
    30541 ttgtccaacc agatgggtag agatcgcata aagccgtaag tcatatttct ttaacagatc
    30601 cttgattcct tgataataag ccgtatccgt acgtcggaca tccacatgat cgggaagtcc
    30661 caattccaca ccgtcgtatc cgaattcttt cgctttttga caaactgttt ccagtgataa
    30721 atctccccac tggagggtat ataatgttac aggacgtgcc atatatagta ttatttttag
    30781 tcgattattt ttatccattt attctctgtc gatccggtag ctacaatcgt ctcgataaac
    30841 cgcatgccac ggacaccgtc ttcggcggaa gggaaatcca aggtttcagg agccggttcc
    30901 tcaccagcca gaatcgatcg caaagccaag gcgaaattcc gatacaaatt agcgaatgcc
    30961 tctatatagc cttccggatg cccgcccggc gtacgggaat tatgagcggc gatacccgac
    31021 atatatccat tggaagtacg gatgatctcc gccggacgat ccggccaacg cataatcatc
    31081 gtattcggtt cttcttgacg ccattccaac ccacctttct ctccatacac acgaatattc
    31141 aagccattct ctacacctac ggcgatctga ctagcggtca gcaccccttt cgcgcctccc
    31201 tcataacgga tcaatgccgc cccatcatca tccaaaagac gatccggcac gaaggtattc
    31261 aattcaccgc ataattccac ggccttcagc cctgttatat attccgccag attaaacgca
    31321 tgagtcccga tatcccccat gcaaccggcc ttacccgacc gattgggatc cacccgccaa
    31381 gccgcctgct tattaacatc agcgcagtca ttatatagcc agccttgagg atattccaca
    31441 taaatacggc gtatcttacc taaatcgccc ctgcgtaccc tttcccgagc ctccttcacc
    31501 atcgggtaag cggtataggt atgagtcagc ataaacaatt ttccggtttc cttcactttg
    31561 tctcgtaatt gcttcgcctc atccaaggta tatgtcatcg gtttatccag tacgacatgg
    31621 aaaccatgtt ccaacgccat catggccgga ccgaaatgca catgattcgg ggtaacgata
    31681 gacacaaaat ccatccgttc gccttcaggc agggtggcct ctttctctat catttcctga
    31741 taagatgcgt aaatacgatt atccggtaaa aataaagatt gtccggtagc caatgaattc
    31801 tccgggcgag aactgaagca tccacagacc aactcgatct gtccgtctaa attagcggcg
    31861 atacgatgaa cggccccgat aaacgagcct tgtcctccac cgaccattcc cattctgatt
    31921 tttcgtttca tggtattatt ccgttttatt aaactaaggt aattacattg ttgattcaca
    31981 aagctatgaa aaataaccct gcgtacgcca atttaacagc ttaatatttt ttaattcaca
    32041 aaatatatcg ttcctttgcg tcaaacatat taccaaaaat ttcaactatg aagaaaaaag
    32101 aattagtggc tatcgcctgt ctgctttgtt tttgttgttg taatggaacg gaaaaggaag
    32161 tacctaaccc cgacctacaa gaggaattat cacccataca gtttacgatc gatttacaaa
    32221 aggaagtatt acccttcccc gtaaccaaga gtattcccga gctgaatatc cctgagccta
    32281 ttccccaaaa tcccgatgcc gaggaagatc cttctacacc agatatcgat ccggataatt
    32341 tatacaaccg gatcgattat atcgtatacc aaagcggaaa accggacatt ctggtaaaac
    32401 ataagcaatt cacgcctcaa gatccggatt tcacgatcat ttatgattca ctgccctccg
    32461 gcaactatca tatttgtttc ctagcccact cagacaagaa tatctccgtg tccggacaaa
    32521 ccgcactatt cagtaaagta tcagatacgt ttcatctttt tctcacccaa gaagtacaaa
    32581 cgggagaaag aatcattaaa gatatcacct tacaaagaat cgtcggcaaa atagagttca
    32641 tatccgccga tggcgtacct aaagccctaa aaagcttcac gataaatgtc tccaattatc
    32701 aaaacaagat tgacttaacc actgggaatg gcatttctca aaacacgcct tatacacaaa
    32761 ccgacacttt taacgactct gatatcggga aaacaaattt ctcccattcc ttcttcacgt
    32821 ttatcccggc tccggaattc atgctcaaag cacacctctc ggccaaaaat cagataaatg
    32881 aagtaacccg ggaaagagaa gttaatgaca tcctgcctct cataaatcac attattcgtt
    32941 atactgggat tctctacacc ccgaaggaat cagacgatac cttcaccctt gatatattaa
    33001 acggtggcaa atgggatagc cccatcgaca aagatctaaa agattaatac aaagccgatg
    33061 tgccaaattt gacacaccgg ctaccttttt cctaaccttc acacttattt tgcgtcttct
    33121 atcttgaaga gagcgttaaa tcccgtcaaa ctaaaggtct cacgaaccac attccgcata
    33181 ccgatcaaac gtaaagaccc tttcttggca gtcgtcattt tttgtaatat taaaaacaat
    33241 cggaggcccg cactactcac atattccaaa tcagaacaat cgacacatac ttttactccc
    33301 ggattctccc ataccggcaa aaccttttcc tcgcattcgc gagccgtatt cgtatccaat
    33361 cttcctttga tcttaattac agtctcttca cctttttggt caataactac ttccatatct
    33421 ttatatttta ttcggttatt tttttcttca tgataaagac attccgctca tctactctct
    33481 gataagagac ctcatccata atcttcttga tcaagaaaat acccaaccct ccgattggac
    33541 ggtcttcggc agataaagta atatcagggt cttttcttaa agtcggatcg aaagcaatcc
    33601 catgatctat caaagtcacg atcaattccc caccttccct gaccaacgaa atgtctacgg
    33661 catcctcaac atctccctta tacgcataaa aaattatatt tgagacagct tcttccatca
    33721 ccagattcag gctcatcatg aaagcggtgc ttaatcccaa ttcttctcca gcttcctcca
    33781 agaactgatt catcatggaa agctcatgaa tatcgttctt aatgcgtaat gttttttgca
    33841 tatatctgaa aattttgcgc taaagatata aaaaaaagaa atatcctttc cttaaatttg
    33901 tatctttacc ttcgaatagt atttaaaggt atagagttat ggctaaaaga tatttaataa
    33961 acatattctt attgatcgcc gtcttatgcg ggttcagtag ttgcgaggag gatccgtatt
    34021 atgatccgta tgaggaaatc acctatgatt tatgtaatta tgtatggact gattggtttg
    34081 tcgtagacgg tttagattgt gagcagcaac ttacatttaa tccggatggg aaaggatggg
    34141 atacaagaat ttaccattac ccaagcggac gcatagatcg agaggaaatt ccattctact
    34201 gggactggaa caattactat accgatatac tttatatgga ctatgaagac ggccaaacaa
    34261 cactagagaa cgtatggatt agtggtcgga cttttaaatg tctatataat ggcgaatggg
    34321 taacgtttaa ggcctatcaa ataggtctct aaaggatatc tttacgtact tccccggcaa
    34381 aatcatacaa tccatcaaaa agacagggat ctttcctcaa ttgttcgaac agtcatacaa
    34441 gtagtctcgc cgggaatcga acccggatct aaagtttagg aaacttctat tctatccgtt
    34501 gaactacaag accaactctt ttgagattgc aaaagtataa tcttttcctc aaatagacaa
    34561 ccgttatcgg atgtttttcc cgcctatccg gaagcttctc attatttccg aaaaaacatg
    34621 tacgtgtttc cggaaaaaca tgtacgtctt tttcaaaaaa cacgtacgtg ttttcaagag
    34681 ctaatataac atcaaataga tcaatcaaat aagctttgca tcaccgataa cgatttgatt
    34741 tccggaaaat ctggaagatg tagacggtaa tactcaagaa tacgatgaat aatacggacc
    34801 cgctcttgcc gggaaaaacc ataaagcgac atattctcaa aactgatacg cagcaaacgg
    34861 gaaaagaaag cgctctccac cttatttaaa taatgccgat gcatcgggat atgatccgta
    34921 aacaccccat tcaacatatc gaaataatat cccaccctat gcgattccat atttgggaaa
    34981 ataccgagat ggtggagaag acctaacaag aaaaccatat gaaaattagc gataccctta
    35041 tccgcatact ccaatagatg tatggactcg cataaataat caaataaacg gggatccggc
    35101 tccgtatctt tcacgaccct aaaaagaacc tccgagagga aaagcgccaa tacattctta
    35161 accggatcac aacaaacatc attcagcgga aaacaaatgc gggtctcctt aatccggtgc
    35221 aagtcccgct tattcaagtg ctccacctcc atttccagaa cggacaaagg tataaacaaa
    35281 gccttcgata ccgtgctttt cttcccacgg ctacgactaa ccagatacga ggcccggcca
    35341 aacgcctccg tatacatata tataatagaa tatttatcat tgtaagggat cgcatgcaag
    35401 acaatccccc tcgttttaca caacataatt cgtatctttg cgacgatgat taagaacaaa
    35461 gatactcaaa ttaacgttat acatataatt aaagtataga attatgttgg acttaacgac
    35521 cccttcttta ttattttccg ccatatcatt gatattgctg gcctatacga atcgcttcct
    35581 ttcatacgcc agcgtagtgc gtgccttgaa agaaaagcat cagcaaaccc atgaccccaa
    35641 ggatatcgcc cagatagcga acctgcggaa aaggctctat ctgacccgtt ccatgcaaat
    35701 attaggaata ctcagtttgc tgctctgcgt gatcgctatg ttcttcattt atgtatcgtg
    35761 gcagattttc gccgcatgga tatttggcat agccttattg ctattagcgg cgtcgttatg
    35821 tgtatgtatc tgggaaataa atatttccgt taaagccttg gaaattcatc tggaagatat
    35881 aagttctaaa gagaagttaa aacagtgagt agtattaaat tttccttcga aatgttttgc
    35941 cagttcggag agatcgtcta tctttgcact cgcaatcggg aaatcacttt cttagaacgc
    36001 tataagtgag agctttgaca ttttggccca ttcgtctatc ggctaggacg caagattttc
    36061 attcttgaaa gaggggttcg attcccctat gggctacaat aaacaggatt aaaaaacaat
    36121 aaagagaaga tcgagaaatg gcaaatcata agtcatcaat caagagaatc agacagacaa
    36181 acgcaagacg tttgcgtaac agatattacg caaagacagc tagaaacgct atgaaagttt
    36241 tgcgcgctac tgaagacaag aatgaggcac aagctttgtt ccctaaggta tgctctatgt
    36301 tggataagct tgcaaaaaag aacgttatcc acaagaacaa ggccggtaat ctgaaatcta
    36361 agttggctaa gcacgttaat gcgctagcat aagcagaagg taattacttt tacaagtata
    36421 aagccggact ctcaataagc ccggcttttt taaacctgat ggcccattcg tctatcggct
    36481 aggacgcaag attttcattc ttgaaagagg ggttcgattc ccctatgggc taccaatcaa
    36541 aaggagagag ataagtttat ggcttatctc tctccttttt tactacaccc gtcctttttt
    36601 cgctattttc acatccccca cttcgctatc tcgataaaaa tcactacatt tgttagattt
    36661 tttttgagga catagataat tacagatttt aaagaaagat aaactcatga gtgaagaaat
    36721 taagaatact tctacagagt actccgcaga tagtattcaa gtacttgaag ggttagaggc
    36781 agtacgaaaa aggccatcca tgtatattgg cgataccagc gagaaaggtc tccatcactt
    36841 agtgtatgag gtcgtagata actccataga cgaagcgcta gccggatatt gtacatacat
    36901 cgacgtggta atcaatgagg acaactcgat cacggttacc gacgacggcc gtggtatccc
    36961 cgtggatatt catgagaaag aaggtaaatc agctttggag gtagtattga cggtgctgca
    37021 cgccggcggt aagttcgaca agggaaccta taaagtatcc ggtggtttgc acggtgtggg
    37081 tgtatcttgc gtaaacgccc tctctactta tctgaaagcg gaagttcgca ggaacggcaa
    37141 agtacatatg caggagttct cttgcggaaa gccgttgcac gacgtacagg ttatcgataa
    37201 tacggataaa acaggtacta cgatctcttt caagccggac ggttctatct ttacggtcac
    37261 ggaatacaag tatgatatct tggctacccg tttgcgtgaa ttagcgttct tgaacgctgg
    37321 tattacgcta cgtctgacag ataagcgagt tctgaaagaa gacggttcat tcaagtccga
    37381 ggtattccat tcggatgagg gattgaaaga gtttgtccgc tatatcgacc gttctaaaga
    37441 gaaactgatt ccagacgtaa tccatatcgt taccgagaag cagggtatcc ctgtcgaggt
    37501 ggcgttaact tataatactt cttacaatga gagcgtattc tcttacgtaa atgatattaa
    37561 cacgatagaa ggtggtacac acttagccgg tttccgccgt ggcctgaccc gtacgttgaa
    37621 aaagtacgcc gaggattcta aattattgga gaaagccaag gtggagattc aaggggatga
    37681 cttccgtgaa ggtttgaccg ccgttatctc tatcaaggta gccgaacctc agttcgaggg
    37741 acagacaaag acgaagctgg gtaatagcga ggttaccggt gcagtggata tggcgatcgg
    37801 tgaggcgtta ggctattatt tggaagaaca tccgaaagag gcgaaaataa tcgtcgacaa
    37861 ggtgatcttg gccgctcaag cccgtcatgc cgctcgtaag gctcgcgaat tggtacaacg
    37921 caaatctccg ctgacaggag gtgggcttcc cggtaaattg gcggactgtt cctctaaaga
    37981 cgcagcgatc tgcgaattgt tccttgtcga aggagactcc gcaggtggta cggctaagca
    38041 aggacgcgac cgtaacttcc aagcgatcct accattgcgc ggtaagatct tgaacgtgga
    38101 gaaagcgatg gatcataaga tcttcgaaag cgaggaaatc cagaacatct atcgtgcgat
    38161 gggcgtaacc gtcggtacgg aggatgaccc gaaagcgttg aacatggaga agctgcgtta
    38221 ccacaaggtg attatcatga ccgatgccga tgtggacggt agccacatcg ccacattgat
    38281 cttgaccttc ttcttccgcc gtatgcgttc cttgatcgag aacggatatg tgtatctggc
    38341 gactcctccc ctctatttgt gtaagaaagg taaggttgag gaatactgct ggaccgagca
    38401 acaacgtcag cagttcatct taaaatatgg aggaggcaac gagaactcga tccatacaca
    38461 acgatacaaa ggtttgggag aaatgaacga ccatcaattg tgggatacga ccatgaaccc
    38521 ggaaaaccgt acgttaaagc agatcacgat cgacaacgca gccgaggctg accaaatctt
    38581 cgccatgttg atgggtgaag acgtaggccc tcgccgcgag tttatcgagg aaaacgctac
    38641 atatgctaac atagatgctt aaaatcatga aagtccgtcg tccgaatcta gaggccctat
    38701 acaaagaagt tgataattat ataccggcta aagaaagcct tcaacctccc cgaataggaa
    38761 tatccgctaa ccggagagac ggactttcct gtatagcgga gacctacgtg caagccgtgc
    38821 tggatgcggg gggagccccg gtacttatcc cggtgatcac ggatctgaaa gcattgaccg
    38881 tactggtttc cgaactagac ggattggtta tgagcggggg tggagacatc aatccgctct
    38941 atttgcatga ggagcctatc ccgcaattgc aagacgtaga tacgttacgt gacgaatacg
    39001 atttgatatt gcttcgcttg gccgctaacc gacaaattcc gatcatgggt atttgccggg
    39061 ggcatcagat catgaatgta gcgttcggag gaagtgtcta tcaagacatc cattcacaag
    39121 ccaatcatgc tctattgaaa cacagccaga cattggctcg ggaatatccg tcgcatacgg
    39181 taacactcga accgggaatg aaccgcctac gtactatttt caatggagaa gaacaaatcc
    39241 ttgtcaactc tttccaccat caagcggtaa aagaggtcgc ccccggattt agagcgacag
    39301 cgaccgcccc ggatggaatc aatgaggcta tggaacatac ggagaaaacg atattcggtg
    39361 tacaatggca tccggaggcc atggctccgc aaggggatga ggccatgaaa gccctattcg
    39421 cttaccatat cgagaatgcc cgccgtttcg caaaagccaa agcgatccat caacggatcg
    39481 tgacgatcga ttcccataca gataccccaa tgatctttcc cggtgaattt aatatcgggg
    39541 agaaagaagg agggaaagtg aatcttcctt ttatggaaga agggcgtatc gacgcaacct
    39601 ttatggtcgc ctatatcccg caaggtaaac gagatgaggc atccttacag gcagcgacag
    39661 cgtatgcgat agaacggctg aatcaagtaa aacgccagca aaccttacat ccggaccgga
    39721 tggttatagc gactaccccc caagagatcc ggacgattaa ggcgcaaggg aaaaaagcga
    39781 tctgcctcgg catcgagaac gggtacgctt tagggaagct ggtcgaaaac ctacgaatgt
    39841 tcaaggagat gggagtttct tatatcacct tatgccataa tggggataac gatatttgtg
    39901 attccgctag aggaaaacag gaatggaaag gactaagtcc tttcggtaag gaagtggtaa
    39961 aagagatgaa ccgattagga atcatggttg atatctcgca tgcggcggaa agtacctttt
    40021 atcaggtact ggaagtgagc gagacgccaa tcatagcctc ccactcttcc gcacgtgcgc
    40081 tttgcgatca tccccgcaat ttaacggatg atcaactgaa agcgctggcc gctcaagggg
    40141 gtgtcgccca aatctgccta tacaaaggat tcatcaataa ggaagaggaa aaagcttctt
    40201 taagcgacgc tatccgccat atcaatcata tcgtggattt aatcggtatc gatcatgtag
    40261 gaatcggctc ggattttgac ggagacgggg aactgatcgg ttgctcggct accaatgagt
    40321 tgattaacat taccgtccga cttttagaag aaggatatac agaagaagat atacggaaaa
    40381 tatggggtgg gaacttgcta agggttatga ccgctataca agattttcca aacaaatagc
    40441 aaacgaaaac aactacatat tatgaaaaat atcttataca cagcaatatg cgcctgtagt
    40501 atcttatgtg gagcacaggc acagacaccc ggatcggaag tccccaactt aaaaaagcta
    40561 tatgagttga cagactcttg cgatgtaaac gtgcgggcac gattctcccc attgatcggg
    40621 atttccgcca gtatctccaa tggtgcttcc cgggtagggg ccacctatat ccaatccatc
    40681 gtaaaggcag ggggaactcc gattatcatc ccggctgtta ctgacggtaa agtactcagg
    40741 aatatcgtat cgaatttaga cgggttagtt cttataggag gagcggatgt aaaccctcta
    40801 tggtatgagg aggagcctcg ggaaaagctg gaggaagtcg atccggtacg cgatttgtat
    40861 gagttgaaac taatcaagat ggctaccgat caaaatattc ccgtcttagg catatgccgg
    40921 ggattgcaac tgttgaatgt agcgtttggc ggtacgcttt accaagacat cccctcacaa
    40981 cgtggcgatc attctgtcaa gcataggcaa gatttaccca gttcgtatgg ctcacaccgt
    41041 gtctttgttg acgcgaactc acagctagcc tctattctag ggaaagatac cttagccgta
    41101 aactctcttc atcatcaagc gatcaaggag ttggcgccta tcttcaaggc taccgcttat
    41161 gcgcccgaca gtattatcga ggctatcgac gcttatccga atcgatccat catgggagtt
    41221 caatggcatc cggaagcgtt gacttacgga ggcgacacta cgatgttaag gatattccgc
    41281 catctgatag gaaaggccga gactttccac caagccaaag agatgcacaa gcatttcctt
    41341 tccgtagata cacataccga tactcctttc tggttcaaac gtgccggatt cagcatcgcg
    41401 gaccgggaac gtaaccgggt aaacatccct aagatgcaag aagggaaact agacggggtg
    41461 ttccttgcgg ccttcatcgg acaaggtaaa cgtgatgagg gctctttaca agaagccgta
    41521 caaaaagtaa caggcttgat cgaaggtatt cgcaagcaag ctgaattgaa taaggattta
    41581 tgtggcatcg ccgttacgaa ccaagacttc atccgcttga agaatgaagg gaaaaaagcg
    41641 ttctttatcg gtatagagaa tggatacggc attggtaagg atctggcgaa tatcgctaag
    41701 ttcaaggcga taggtgtcaa ttatatcacg ctctgccact cctacgataa cgatatttgc
    41761 gactcatcca cccataccaa gaaagaatgg gacggtttaa gtccgtttgg tgaagaggtt
    41821 gtgaaagaga tgaatcgcca aggtatcatg gtggatatgt ctcatgcctc tgagaagtca
    41881 ttttgggatg ttatcaaatt gtccaaggcc ccgatcatct gctcgcattc ctcatccatg
    41941 gcgatgtgca agcacgaccg taacctgacc gacgaacaac taaaggccct tgcccaaaat
    42001 ggaggcgtag cgcaagtttg cttgctcgac cgctatatca atgaggatta taaaaacgcg
    42061 agccttaccg acgcgatcga acatatcgat catatggtga aagtcgccgg tatcgatcat
    42121 gtaggtatcg gctctgattt tgatggcggt ggcggaatta tcggttgcga aagtgacaac
    42181 gatttcatac agatcactgt taaattaata gagaaaggat atacagagga agatatcgcc
    42241 aagatatggg gtggaaactt gatgcgtgta ttagacgagg ttcaagcgac tgcctccgta
    42301 aaaacattat aaacaaaaca gatttatgat cagattattt tttgcgttat tgagttttgc
    42361 tcttttatca tgtggagcca aaggaaccaa agagacaggt aatatgccgg agatcaaaaa
    42421 acaaccgatc gcctcagctg ttcccgattt caacgcagac agcgcttacg cctatgtagc
    42481 gaaccaagtc gcttttggtc cccgtgtacc taacacggcg gctcataaag catgcgggga
    42541 ttacttagca tctgaattga agcgctttgg cgccaaagtc taccaacagg aagcgatact
    42601 gaccgcctac gacggaacga agctggaagc gagaaacatc ataggctcgt ttgatccgga
    42661 gaatagtaaa cgtgttttac tattcgcgca ttgggacagc cgtccctatt cggaccacga
    42721 tcccgatcct tccaagcacc ggaccccatt ggacggggcg gacgatggcg gtagcggcgt
    42781 aggtgcctta ttggagatcg cccgccaaat cggacaaaaa gccccgggta tcggtatcga
    42841 tattattttc ttcgatgcgg aggattatgg tacgccggaa ttcgtaaccg attatacacc
    42901 ggatagctgg tgcctaggta cccagttctg ggcaaaaaat ccgcatgtcc ctaattatac
    42961 ggcggaatac ggaatcttat tggatatggt gggcggcaag aacgccacgt ttttcaagga
    43021 gcaacaatcc ttacgtgcgg cagccccgat cgtcgagatg gtatggagcg cggcccgcga
    43081 tctgggatat ggcaaatatt tcattaacgc caccggcgga gcgctcatag acgatcacca
    43141 atatgtgatt agcggacgta atatcccgag tatcgacatc attaactacg accctgagtc
    43201 taaaacaggt ttcgccagtt attggcatac tcaaaaagat aatatggaaa atatagaccg
    43261 tgagactcta aaagctgccg gtcaaaccgt actggaagta atatacaatc gataaaatac
    43321 tgataaaatg acaatcaatg aacttcaaga caatgtaatc gaagaattct cagtcttcga
    43381 cgattggatg gacaaatatg cgttattaat agatctggga aattcacttc ccccgcttga
    43441 tgagaaatat aaaacggaaa gcaacttgat cgagggttgt caaagccggg tttggttcca
    43501 agcggattat gtggatggaa agattatttt ccaaggagaa agcgatgccg tgatcgtaaa
    43561 aggtatcgta tctttgctga tacagatctt atcgggccat acccctcaag aaatcttgga
    43621 tgcggatcta tactttatag acaaggtagg attaaaagag catttatccc ctacccgttc
    43681 caacgggttg gtagcgatgg tgaagcaaat gcgtctgtac gcgatggctt accgggcaaa
    43741 ggaacaacaa taaaaacagg tgttttcaca cgtatatagg cacgagccga tacgtatata
    43801 cgtgtaagcc tacaccgata taggcatagc ctcatacgta tatacgcata aggttatgcc
    43861 tatatacgta ttaaaaaccg agtgtaagct gctccggtaa gagcgtaaaa gtcttgcgat
    43921 gataaggcgt gattccgtgg gtacgaatcg cttccctgtg gaccttggta ggataacctt
    43981 tattgtccag ccaatgataa gcggggtatt ccaaggccaa ttcattcata taatcatccc
    44041 gataggtttt agccaatata gaggcggcgg cgatactcag gtatttgcca tcgcctttta
    44101 ctacggtcgt atgtggaata tcgggataag gggtaaaacg gtttccatcg atcaataaat
    44161 gttccggccg tactttcaat tgctcgatcg cacgatgcat ggccaagaaa gaggctttca
    44221 aaatattaat cttatcgatc tcttccgggc taacgatacc taccgcccaa gcgatcgcct
    44281 cacgctcgat aacgggacga agcttatacc gtttcttctc gcttaattgc ttgctatcgt
    44341 ttaaatcctc attcttaaaa tcttccggaa gaatcacggc ggcggcgaat accgcacccg
    44401 ccaagcagcc tcttcccgcc tcatcacacc cnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    44461 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    44521 nnnnnnnnnn nttcacaatc caagggcgaa gcacgaacca agcgaatgcc gtagcggcga
    44581 tcaccccgca agtattcgcc aagaaatcaa accaatcccc accccggtac gtcgtacaat
    44641 attcttgcaa tatctcaata atcccactca taacgatcgg gcataaaacc gccccgatcc
    44701 aagcatgcca taataccgtc tcatacttcc ggtgattccg caagaactcc agccatagca
    44761 tacccgacat ccccccatac atacagaaat gaaccacctt gtccacaccc gggaataaag
    44821 ggatatcatc catcctcggc ggcttaaaga acgacaagta aataacgatc aatataatcg
    44881 ccagtgaaaa cggatatttc ttaatataat acatcatact caaaacatct tccgaactcg
    44941 ttccacacct gcgatgaacg tatcgatctc ctctttcgta ttataaaagg agaaagacgc
    45001 ccgcaccgtc ccctcgatcc ctaaggcatg catcaaaggc tgggcacaat gatgccctgt
    45061 acgaaccgct attcccaaac ggtccagcaa catccccata tcgtaatgat ggatattacc
    45121 caccaaaaaa gaaagcaccg ctcctttatg atccgcttgt ccgaaaatac gcatcccttc
    45181 gatcgtattt aatccagcgg tcgcatatcg caaaagctca tcctcataag cagctatatt
    45241 ctctataccg atccggtcta cataccgcaa ggcttccgcc aacgccgtgc taccaatata
    45301 atccggagtt cccgcctcaa acttaaaggg aagctcatta aaagttgtct tctcgaacga
    45361 gaccgtagca atcatctcgc ctcctccctg atacggagga agtttatcca accactcctc
    45421 tttgccatac aagaccccga tacccgtcgg tccgtaaatc ttatgaccag agaaaacata
    45481 gaactccgca tccaagtcct gcacatccac cttcatatgc ggaacggctt gagccccgtc
    45541 taccaacacc ggcacgcctt gttcatgagc gatctcgatc atcgccttta ccggatttac
    45601 cgtacccaag acgttagaca catgagtcac ggaaaccaga cgagtcttat ccgagaataa
    45661 tttacgatac tcatccagat tcaactcccc tttctcattc atcgggatca ccttcaacgt
    45721 aatacctttc cgggccgctt gtatctgcca aggaacgata ttggaatgat gctccatcac
    45781 ggacacgatc acctcatccc ctgccgacat acattcatcc gtaaagctgg aagcgatcag
    45841 attgatggat tccgtagttc cccgggtaaa aataatctca ttcgaggaac gggcattcaa
    45901 gaaatgctgt accgttttgc gagcctcctc atgcgcctct gtcgccgctt ggctcaagaa
    45961 atgtacgcct cggtggatat t
//
LOCUS       DBMDTB010000019        45684 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_324_length_45684_cov_12.228265, whole genome shotgun sequence.
ACCESSION   DBMDTB010000019 DBMDTB010000000
VERSION     DBMDTB010000019.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 45684)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 45684)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45684
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_324_length_45684_cov_12.228265"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..2084
                     /locus_tag="ACZPB4_05110"
     CDS             <1..2084
                     /locus_tag="ACZPB4_05110"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HIR1097634.1"
                     /translation="SSIVGFSHTHFSGTGHSDLGDILIMPTTGTLKLNPGTATNPDGG
                     YRSRFSHGTEISRPGYYEVMLTDYGVKAQLTTTQRVGIHKYTYPTNSENQRIILDMIH
                     GIYNYDGKVLWTNIRVENDTLVTGYRITNGWARTNYTYFAMSFSKPITHYGCEEKAKV
                     NYRGGYAKFNMKENFPNIGGRKIVAYFDFDPKTSDELEVKVALSGVSTEGALKNLRAE
                     ASGADFDQLAAKASDTWNKALSVIDAKGSDDQLAMLYTSLYHTMINPCVYTDVDGQYR
                     GLDHNIHQADGFTNYTVFSVWDTYRALHPLFNIINRQVNTDIAKSMLKHCEQSVHHAL
                     PIWSHMANENWCMIGYHSVSVLADAIAKGLPIDKDAALKAMISSSTIPYYEGTKEFME
                     LGYVPLDRNGSAGSLTLEYAYDDWTIYNTALLVGNRSVADTYKKRASNYANVFDTSIG
                     YARPRYTNGKFKEDFSLLSTHGEGFIEGNALNYSFYVPQDVNGMIQLMGGEQAFITKM
                     DSLFTMHLPDEFFAETEDVTKEGLLGGYVHGNEPSHHIPFLYAWTSQPWKTQFWQREI
                     MNKMYRNNIDGLCGNDDCGQMSAWYILSAMGFYPVCPGTDQYVLGAPYLPYMKVRLEN
                     GKTFEVKANKVSDKNRYVKAVKLNGKPYTKGYITQDDIMNGGTLTFEMTSSPNKKRLF
                     NGEDRPYSLTD"
     gene            2116..2913
                     /locus_tag="ACZPB4_05115"
     CDS             2116..2913
                     /locus_tag="ACZPB4_05115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="basic secretory family protein"
                     /protein_id="HIR1097635.1"
                     /translation="MKYKQLISGAFLLWTCIACSGKKEQAATVAEATSNPWDNYYIGK
                     IDFKNLSPEAKGSAIYAAVIPDPEAYITKHARKVVETLYFTPEDSIPGIEEIHYTLKE
                     YDGVSAKDGAPPSISIVYSTKWIEKSFANNDTAKVDYETRGVLYHELTHGFQLEPQGI
                     GSYGTNKTFWAMIEGVADAVRYLNGGFTLEDRPKGGHYMDGYRTTGFFLAWLTQTKSP
                     DFLRKFNRSTLEVIPWSFDGGVKYALGNDYDIDSLWKEYMATMGDEA"
     gene            3152..4138
                     /locus_tag="ACZPB4_05120"
     CDS             3152..4138
                     /locus_tag="ACZPB4_05120"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GSCFA domain-containing protein"
                     /protein_id="HIR1097636.1"
                     /translation="MELYTRILLPKARFSFSYEDRVVMMGSCFAENIGRKLEENKFSV
                     DINPFGTLYNPASVAEGLRMLLRPERFTPGDLFQHEGIYHSFTHHSRFSAPSEEECLG
                     HINSRLSESSDFLRKATRLVITLGTAFVYRLKSDGRIVSNCHKLPEKMFDRQRLSTQE
                     IVEDWKPLLLALWEQNPALKILFTVSPIRHWKDGAHENQLSKATLLLATDALQKDYPD
                     RIAYFPAYEILMDELRDYRFYADDMLHPSPLAIDYIWQRFIENFLSTDTSAILKEWGD
                     IQKAINHKPFQPDSEAYKRFILQTLLKMERISEKIPSFDIRKEIEIVKSKLK"
     gene            4143..6608
                     /locus_tag="ACZPB4_05125"
     CDS             4143..6608
                     /locus_tag="ACZPB4_05125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008784 - alanine racemase activity
                     [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006522 - alanine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine
                     ligase/alanine racemase"
                     /protein_id="HIR1097637.1"
                     /translation="MEYAIKEIARVIGAKTNQLLDDTVSLLLTDSRRLSFPEQSLFFA
                     LKTKTNDGHRYIQELYKLRVRNFVVSDMLPEFESMKDANFLIVKDTLRALQKLATHHR
                     KQFNIPVIGITGSNGKTIVKEFLYQLLHNEFNIVRSPRSYNSQLGVPLSVWQMSEKNT
                     LGIFEAGISQPDEMERLQPIIAPTIGIITNIGEAHQENFLSSNQKCMEKLTLFNDCEA
                     IIYDGDDLFIANCIESACLSHKAIAWSRTDSEAPLFIESIDKKEFETIIHCTLLGFNR
                     VVTIPFTDDASIENVIHCMAVMLYLKPTSVNDVTKFLHLEPVAMRLDVKQGINNCLLI
                     NDTYNSDINSLDIALDFQQSRRVGKQLKSTLILSDILQSGTLPKSLYKKVADLVRRKK
                     IDRIVGIGRDLKEYASVFEIEKEFYTTTEEFIKSPSFKKFKDELILIKGSRHFHFEQI
                     SELLEKKVHETILEVNLDAIVHNFNQYRSKLKPETKMVCMVKAFGYGAGSYELAKTLQ
                     EHRCDYLAVAVADEGAELRKEGISIPIIVMNPEFSSFNVLFENHLEPEVYSFRLLDAM
                     IRETERRGITSYPIHIKIDTGMHRLGFQPEDVPAICERLRAQSGVIARSVFSHLAGSD
                     SYVFDDFTHQQLDKFTKAAGELENGLEYKVIKHILNSAGIERFAAYQMDMVRLGIGLY
                     GVSASGQKGLRNVSTLKTTILQIQNVPAGDSIGYSRMSYVKRDSRIAIIPIGYADGLD
                     RHFSNGGGEVLINGQRCPIIGNICMDACMIDVTDIHAQEGDAVIIFGDELPVSELSDK
                     LKTIPYEILTSISPRVKRVYFRE"
     gene            6744..7601
                     /locus_tag="ACZPB4_05130"
     CDS             6744..7601
                     /locus_tag="ACZPB4_05130"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013264050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004318 - enoyl-[acyl-carrier-protein]
                     reductase (NADH) activity [Evidence IEA];
                     GO_process: GO:0030497 - fatty acid elongation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HIR1097638.1"
                     /translation="MSHNLLKGKRGIIFGALNDMSIAWKVAERAVEEGATITLSNTPI
                     AVRMGQVDALAEKLNAQVIPADATSVEDLETVFAKSVEILGGKIDFVLHSIGMSPNVR
                     KKRTYDDLDYGMLEKTLDISAISFHKMLQVAKKQDAIAENGSVVALSYVAAQRTFFGY
                     NDMADAKSLLESIARSFGYIYGREKGVRVNTISQSPTMTTAGSGVKGMEHLMDFSNKM
                     SPLGNANADECADYCVMMFSDFTRKVTMQNLYHDGGFSSMGMSLRAMNQYSKGLEEYT
                     DENGHVIYG"
     gene            7603..8205
                     /locus_tag="ACZPB4_05135"
     CDS             7603..8205
                     /locus_tag="ACZPB4_05135"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HIR1097639.1"
                     /translation="MLVKIYPENPNQKEIDKVVKVLQDGGLVVYPTDTVYAIGCDALN
                     VRAVEKICQMKGVNPQKSNLSIICYDLSNLSEYAKVSNAAFKLMKKHLPGPFTFILPT
                     SSELPKIYKNRKEVGIRVPDNNITRTLVQSLGNPILTMSIRDEDEVIEYTTDPELIHE
                     KYEHQVDIVIDGGFGGLEASTVIDCTTDNFEIVRQGKGEL"
     gene            complement(8184..10817)
                     /locus_tag="ACZPB4_05140"
     CDS             complement(8184..10817)
                     /locus_tag="ACZPB4_05140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase 2 galactose-binding
                     domain-containing protein"
                     /protein_id="HIR1097640.1"
                     /translation="MMNRCIYLFCWLCLACWSKPVSAEGQALLVIPEPGEKTLIHSDW
                     YARKANEVKMDGNRLSAVPLDKTGWLPARVPGTVLTTLLENGLYPAPEFGLNNNLIPD
                     IHEVGNDFYTYWFTRQFTIDALPEGRNVWLNFRGINYKAEIFLNGKRINRNTHEGMFL
                     RKTFNITPYLRTDAPNVLAVLVYPPTHVGNPNGGQGGDGQIARNNTMQYTPGWDWIQP
                     VRDRNTGIWDEVSITTTGPVCLSSPYVVTKVPGVRDPETKTQKEAFVNTSVELENTGS
                     TSLKGLLVCETNGTRLTQPVTLSPFEKKTVSLNPLAVKNPRLWWPNGIGEQPLYDMNL
                     SFEIGNQVSDRERLRYGIREITSDKCPDNGGRRFFVNGQKIYVTGGNYINSDWLLRLS
                     PERYRDEVRFHAEMNLRMIRVWGGALVERPEFYNACDEFGILVFQDLWGSGDCNGAWE
                     DPTKMDSRERRWEYPDNHDLFIASVEDQVKMIRNHPSLCFWCGANEWPLAKDIDQCLR
                     KEVFPRLDPERLFVSFSTDTLFTRNYLGDNGDGPYGIQEPEWFFSFRSHPFNPEAGSV
                     GSPEVESIREMMTEQDLAGFPRKGFTRNYTWRYHKDLGYGDHLERYGEVKDIETYCKY
                     AQVVNYDQYRSFMEGWASHMWDWYTGILIWKTQNPWTSLRGQMYDWSLDVNASLYGTR
                     KGCEPLHAYYNPVTRKAGLLNTTLKDYTDLSIVARIYNLEGKLLWEKETRASAKANTV
                     QELLDIPVPEGIKGAYFLRLALNADVPNIYWLTTEPKDYTSLSQLPKSRPGIKTEIKK
                     EGSNFVGTVRLSADSQISFFNRIKVFDKETGKRILPVHYSDNYITLMPGDQQEISLEF
                     PANLPEERIQIVVDSYNSPLP"
     gene            complement(10931..12586)
                     /locus_tag="ACZPB4_05145"
     CDS             complement(10931..12586)
                     /locus_tag="ACZPB4_05145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SusD/RagB family nutrient-binding outer membrane
                     lipoprotein"
                     /protein_id="HIR1097641.1"
                     /translation="MKLNRILKYAAVSALVVSTGVMTMGCTDNFENLNTDPYEVDPDE
                     LPFSAQFKEPFSYVYAPQQNLFQYCFNLNIDLFSGYFMTPHNFNGSGNVDYALNRGFC
                     GGMYENVYLHIFNNTRRLIASCDEQGLSDYGAMMRVVQAYAIQMLTDAYGPVAYSSVI
                     EDPTGGASFSYDTQESVYNALFTLVDEAIAGFKGTASVADMQAFDYWCNGDIALWKKV
                     ANQLKLRLAMRIVKVNPTLAKQKAEEAVQGGVLTSADRDILINQGLSNELTRMFEWGD
                     CGMNASLITMLEGFKDPRLPLYVTKNQAAVTCEDGSTIEEGTKYLGVRGGCNLPSKPN
                     QWGNFSKVICTYTTAFPVMKVAEGYFLRAEGALRGWSMGGSAKDLYEEGIRISIKNEL
                     AYKGSIAGVTSISDAEIDAYLNGTSGQIDFVDPVKAENSIKAMNTLGVKWDEGASKEE
                     KLQRIITQKWIANFPLSCEAWAEYRRTGYPKLFPNRVNLSNGDINTNEQVRRLIYSDT
                     EINTNNAELQKGIELLNQENTGSISGDKGGTHVWWDKAGVGNF"
     gene            complement(12603..15635)
                     /locus_tag="ACZPB4_05150"
     CDS             complement(12603..15635)
                     /locus_tag="ACZPB4_05150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007833883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SusC/RagA family TonB-linked outer membrane
                     protein"
                     /protein_id="HIR1097642.1"
                     /translation="MRKSFILLLAFFLCVTGYAQKLTISGVVIDKDLNEPLTGVNVLV
                     KGTTTGTITDFDGKYTLEADANSILVFSYLSMKTIEEPVNGRTKIDVTMVSDAEALDE
                     VVVTAMGIKRESKTLTYSAQTVGGKDLNEIKNVNMINSLQGKSAGLQITPNSTGAGGS
                     SKILFRGNKSISGSNQPLIVVDGVPMMMSVSDSQVKMAYGGERDGGDAMSTINPDDIA
                     QITLLKGASAAALYGAVAANGAIMITTKSAQAGKVAINVSSNTTVESAMSLPKFQNNY
                     GMSDEGTFSWGSKLGATSPNYARKFYQPGYTTNNSISLSGGTENISSYFSYANVSSNG
                     IMPENDYLSHNLMAKVGFNLWKKVHVDVSARYNKQHIENQPSAGYLNNPITGAYLFPR
                     GEDWDYYKSNYEVYDGVRNVNVHNWTNTKQEQFSNPYWMLNRQTPITDRNRYEFGGSV
                     KYDIMEGLSVTGRLRYERGDEKWILNEYASSTAGRNLLGTMKDTRTFSEQTYADALAS
                     YNKTWDETYSLSVTAGGSFTKTSASSIELIGWGDKEFKVNNGVITPGAYYPNIFSPKN
                     YYTMQTTETLKEKRLNSVFATAQFGYKEGLFLDVSARNDWSSSLAFTDGVSFFYPSVG
                     VSALLDKFLDFGKNVDLFKLRASYSIVGNDVPIYASNKRYTIGDQGSIDPPEEAAFRT
                     LKPEKTNSLEVGFDGTFFQNRFNVNLTYYKTNTKNQYFNITAPWETGLKNRYINAGNV
                     ENQGFEVSLGWYNQFTDNFSWSTNFNFSYNNNKIIELSNELKDWTLASYCTGAKVILT
                     EGGHFGDLYVRDFKRDDNGKPVKTESGAPELGGTDNKDLVYVGDMNAKVNMGWTNTFH
                     YKDFTLSFLIDAKVGGKVLSMTEATLDGWGVSERSGAARDAGEVVIDGVSFDPKAYYT
                     TTGGTSYNSNILTSQYVYNATNVRLRELSFGYTFRNLFGANKNLTASIIGRNLFFFYK
                     DAPMDPDVAAGTGNGWQGVDMFALPTSRSFGLNLKLNF"
     gene            16259..17584
                     /gene="dgt"
                     /locus_tag="ACZPB4_05155"
     CDS             16259..17584
                     /gene="dgt"
                     /locus_tag="ACZPB4_05155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008832 - dGTPase activity [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dGTP triphosphohydrolase"
                     /protein_id="HIR1097643.1"
                     /translation="MNWTQLLSGKRFGMEEYHERKHERTDFQRDYDRLIFSSPFRRLQ
                     NKTQVFPLPGSIFVHNRLTHSLEVSCVGRSLGNNVAKGLIQKYPDGSINFPEIGSIVS
                     AACLAHDMGNPPFGHSGERAISAYFSEGNGRKLEEKVRKERGRWEDFVHFEGNANAMR
                     LLTHQFIGRRKGGFALTYSTLASIIKYPYASIYSGKKGKFGFFQSEEGSYLQIAQELG
                     IGHNPEAPDKFLRYPLVYLVEAADDICYQIMDIEDACKLHILTTEEAIQLLLGFFEGE
                     RLEHIRKVMHMVDDTNEQIAYLRSCIIGLLVDECSRVFLENEESILNGTYSTPLISNI
                     CDQAKQAYANCSATAYKKIYKAKEVLDIELAGYHIFSHLIDSLTEAVMNQEHAYSKLL
                     LQRIPEQYDTNAPTTYGKIQCVLDYISGMTDVYALDLYRKITGMSLPAV"
     gene            complement(17600..18532)
                     /gene="rsgA"
                     /locus_tag="ACZPB4_05160"
     CDS             complement(17600..18532)
                     /gene="rsgA"
                     /locus_tag="ACZPB4_05160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HIR1097644.1"
                     /translation="MRGLVIKNTGSWYTVRTEDGRDIESKIKGNFRLKDIKSTNPVAV
                     GDRVVIDINKEGTAFITEIEERKNYIIRRASNLSKQSHIIAANLDQAMLIVTVNYPIT
                     TTIFIDRFLATAEAYRVPVKLVFNKIDRYNNEDQRALENLIELYTSIGYPCSTLCARA
                     EEGLDALKADLKDKITLLSGHSGVGKSTIINKLVPGVNLRTGDISEYHNKGMHTTTFS
                     EMISLPGGGYLIDTPGIKGFGTIEMADAEISHYFRELFKYSEECRFNNCTHRHEPGCA
                     VIQAVNDGLISESRYKSYLSILDDRMESKYREEF"
     gene            complement(18628..19191)
                     /gene="frr"
                     /locus_tag="ACZPB4_05165"
     CDS             complement(18628..19191)
                     /gene="frr"
                     /locus_tag="ACZPB4_05165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HIR1097645.1"
                     /translation="MIDTKQLIKAGEEKMTFAIEYLDEQLSHIRAGKANPKILDCVKV
                     MYYGAPVPLTNVATVTVPDARTIMITPWEKKIIRDIEKGILDSELGITPENNGEVIRL
                     GIPPLTEERRRQLVKQCKQEAENAKISVRNARRDAIEALKKSIKSDGVPEDVEKDAEA
                     EVQKIHDKFIKKIDELYAAKEKEVMTV"
     gene            complement(19319..20485)
                     /locus_tag="ACZPB4_05170"
     CDS             complement(19319..20485)
                     /locus_tag="ACZPB4_05170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HIR1097646.1"
                     /translation="MSEKTSSLKLIPVMLAFFAMGFVDLVGIASNYLKADLGLSDSEA
                     NIFPSLVFFWFLIFSVPTGMLMNRIGRKKTVLLSLIVTFLSLMIPIFDDAYMVMLISF
                     SLLGIGNALMQTSLNPLLSNIVSGDKLASSLTFGQFVKAIASFLAPYIAMWGATQAIP
                     SMELGWRVLFPVYMVIAVIAILLLGATTIHETKEEGRPSTFGECLALLGKPFILLCFI
                     GIMCHVGIDVGTNTTAPKILMERLGMTLADAGFATSLYFIFRTAGCFSGAFILRKVSP
                     KGFFAFSVFLMLLAMIGLLLFHSKEIIYACIALIGFGNSNVFPIIFAQALLSMPNKQN
                     EVSGLMIMGLFGGTIFPIFMGVASDMLASQVGAVLVLCVGVAYLLFFTPKLSKQ"
     gene            complement(20489..21361)
                     /locus_tag="ACZPB4_05175"
     CDS             complement(20489..21361)
                     /locus_tag="ACZPB4_05175"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase family protein"
                     /protein_id="HIR1097647.1"
                     /translation="MEKSKPVVVGIGELLWDVFPDVKKAGGAPINFVYHATQLGAEGY
                     AISAVGNDVFGTEIIQELDKNGIDSNYISTVEYPTGSVMVELKNGIPSYTIIEGVAWD
                     HIPLTQASIDLMKRADAVCFGTLAQRAAESRETLRTLLSYMPSHALRFFDINIRQHFY
                     SKELIESLLELANVFKINDEELEMLRPMFGLEGTIEDMCRWFMKKYGLRYLVLTAGAE
                     YSTIFSEEEVSTIPTPKVQVVDTVGAGDSFSGAFISSILTGKPLREAHEKAVKVAAYV
                     CTQSGAWPAYPKDL"
     gene            complement(21380..23188)
                     /locus_tag="ACZPB4_05180"
     CDS             complement(21380..23188)
                     /locus_tag="ACZPB4_05180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4980 domain-containing protein"
                     /protein_id="HIR1097648.1"
                     /translation="MKQQTKRLLKSLCMAVGIILLSAVDPLAGYAAERTIDIKHLGEG
                     QSIVRVDARAKYLLLPVEESSPESKLYMIVDNDVVRTFNVRLAVNKVDYFVPVDLSGY
                     ADKHISFNFQLAPESALCWKEMKLSDQFDSSNREKFRPAYHFSPAWGWMNDPNGMVYK
                     DGEYHLFYQYNPYGSMWGNMHWGHAISKDLIHWEHQPVAIAPDALGTIFSGSCVVDKD
                     NTAGFGAGAIVAFYTSASDRQVQSMAYSLDNGRTFKKYDRNPILTSTQRDFRDPKVFW
                     HKESNKWIMVLAVGQEMQLYSSPNLKDWTYESSFGEGQGAHAGVWECPDLIELPMKGT
                     ELKKWVLICNINPGGPFGGSATQYFVGAFDGKQFVNESPALTKWMDYGKDHYATVTWS
                     NAPEDRKIALAWMSNWEYANNVPTLQYRSANSVPRDLVLYTKNGQTYLSSTPSPEVLK
                     LRGKAQKKGSFKVDRSHEVNPVLPDPTGTYEIEIKFKNNGADIMSFQLFNSKGEEVEM
                     RYNLLDNTFTMDRRNSGITDFSKTFATATSAPISAAKEYTLRLLVDKSSIEAFDGNGE
                     FVMTNLVFPEEPYNRISFHAKGGAFTVTSLTIYPFK"
     gene            complement(23317..25980)
                     /locus_tag="ACZPB4_05185"
     CDS             complement(23317..25980)
                     /locus_tag="ACZPB4_05185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HIR1097649.1"
                     /translation="MKHPFLLVWLTLIVLCGCTSSGKQKRHVIGLSQCMLDDAWREAM
                     INDMRIEASNYDDMEIIIKDAQNNNETQIQQIRDLIRQKVDVLIISPYQSEPITAVAE
                     EAYRAGIPTIITDRKVNTDQYTSFVGANNYEIGLAAGNYAANYLPPNAIILEIWGLTQ
                     TSPAQERHKGFVDALREREDLSFRKIEGQWLVDTARMELRKLEHPEQIDFVYAHNDMM
                     AIAAREYFMAWDSIRGRDLRIIGVDAVAGAGLEAVEDGRINASFLYPTGGEQVIRTAM
                     RIIQGEPVDKFIPLRTAPVDHQSARTLLLQADQLQKYKQRIEAQRSRIDGLSDRFYFL
                     RNSLGVISLLMIGFIALSIYAFYINRKMRQANRKLISLNAEMKEVTAQKLQFFTNVSH
                     EVRTPLTLILAPLDRLIISLRESPYASDLGLIQKNANRLLRVINQILDFRKVEGKQEK
                     LAVREIDLVPFVGEIKSYFDSMASVRAIAYTFTSSIKQCTLWIDPDLLEKVFVNLLSN
                     AFKFTPEGGSVRIELTEEEDRVFIQVIDTGSGIQPGNLPHLFDRFYTEDRSMGTGIGL
                     HLVKEYIHMHGGEIRVESEPGQRTTFTVCLRKGKAHFEDSDLMETSVSHQAYEASRLD
                     DSETHKMLSKTYPYTILITEDDDEVRCFLERELSPHFKTRTAANGKDALRVLEEEEIS
                     LVVSDVMMPEMNGFELCRMIKSQLPFSHIPVILLTALTDERQRIFGITGGADDYIQKP
                     FHTDYVKIKIIHLLQERQKLRERLLEKLRDNKLLLSEPEKVESIDDAFLRKFAEQIEA
                     VYADPEYNVEKLSETLGLSRGHLHRKIKELTGTAPVEFLRTYRLNKATQLLRQNAYTV
                     SEVAYRTGFSSPAYFSKCFKAVYGVTPTEYQ"
     gene            complement(26091..26801)
                     /gene="pyrH"
                     /locus_tag="ACZPB4_05190"
     CDS             complement(26091..26801)
                     /gene="pyrH"
                     /locus_tag="ACZPB4_05190"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005784714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033862 - UMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HIR1097650.1"
                     /translation="MAQYKRILLKLSGESLMGGKQYGIDEVRLNEYAAQIKEIAEMGV
                     QIGIVIGGGNIFRGLSGASKGFDRVKGDQMGMLATVINSLALSSALVAQGVKAKVLTA
                     IRMEPIGEFYNKWRAIELLEQGNVVIMSGGTGNPFFTTDTGSSLRGIEIEADVMLKGT
                     RVDGIYTADPEKDPTATKFSDITYDEIYTRGLKVMDLTATTMCKENNLPIIVFDMDTN
                     GNLKKVMSGENIGTLVHN"
     gene            complement(26959..28161)
                     /locus_tag="ACZPB4_05195"
     CDS             complement(26959..28161)
                     /locus_tag="ACZPB4_05195"
                     /EC_number="2.7.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_function: GO:0016774 - phosphotransferase activity,
                     carboxyl group as acceptor [Evidence IEA];
                     GO_process: GO:0006082 - organic acid metabolic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetate/propionate family kinase"
                     /protein_id="HIR1097651.1"
                     /translation="MKILVLNCGSSSIKYKLFDMTSGEVMAQGGIEKIGLPGAFLKLT
                     DKDGKKVVIEREIPGHQEGIEFILSVLTDATYGCIKDYKEIDAVGHRVVHGGEEFASS
                     VLINQDVINKVIECSDLAPLHNPANLKGVRAMEALIPGIPQVAVFDTAFHQTMPDYAY
                     MYGLPYEMYKKYGVRRYGFHGTSHRYVSRRACEILGVPYEDQKIITAHVGNGGSITAI
                     KNGKSVDTSMGLTPVEGLLMGTRCGDVDAGALSFIMDKEGMDGAGLSDLINKRSGVAG
                     LSGISSDMREIEAAVAAGNPRAIMTLNVYNYRIKKYIGAYAAAMGGCDILVWTGGVGE
                     NQWATRRAVCENMEYMGMKIDVEKNEGMRGEEMVISTPDSKVTIIVVPTDEEFMIAAD
                     TLEILDKK"
     gene            complement(28188..29201)
                     /gene="pta"
                     /locus_tag="ACZPB4_05200"
     CDS             complement(28188..29201)
                     /gene="pta"
                     /locus_tag="ACZPB4_05200"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009016811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008959 - phosphate acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006086 - pyruvate decarboxylation to
                     acetyl-CoA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HIR1097652.1"
                     /translation="MDLMQDIIARAKADKQRIVLPEGTEERTLKAADRLLADGVADII
                     LIGNPAEIKELAAGFGLNHIGEATLVDPKNHEKKAAYADLLFQLRQKKGMTPEKAAVL
                     VEDPLFLACLMIKAGDADGEIAGAENTTGNVLRPALQIIKTAPGMKCVSGAFLMFTKT
                     PQYGDDGILVFADCAVMPNPNAEELASIAVATAATARNIVGVEPRVAMLSFSTKGSAS
                     HEMVDKVVEATRLAKEMAPDLKIDGELQADAALVEAVGSKKAPGSEIAGKANVLVFPT
                     LEVGNIAYKLVQRLGGAEAVGPILQGMAAPVNDLSRGCSVDDIYKMVAIACNQSIGLK
                     SAK"
     gene            complement(29329..30114)
                     /gene="cdaA"
                     /locus_tag="ACZPB4_05205"
     CDS             complement(29329..30114)
                     /gene="cdaA"
                     /locus_tag="ACZPB4_05205"
                     /EC_number="2.7.7.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005634496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004016 - adenylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0006171 - cAMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diadenylate cyclase CdaA"
                     /protein_id="HIR1097653.1"
                     /translation="MWMHFGIKDLIDVLLVAFFLYQTYKLMKSSGTLAIFSGVVSFIV
                     VWILISQVLEMRLMGAILDKFISVGFVVLVILFQDEIRRFLLALGSHRGWKFLGKLFS
                     KRGDDPEKEGKFVAPVVLACMNMARKKTGALIVIQQDMDLTIYEHTGEMFNADVNARL
                     IENIFFKNSPLHDGAMIIADNRIKAAGCILPVAQNATLPKDMGLRHRSGLGMSLETDA
                     LVIIVSEERGKISVAHKGKLSVNVTAEELQQILSGEREVTNYC"
     gene            complement(30149..30988)
                     /gene="folP"
                     /locus_tag="ACZPB4_05210"
     CDS             complement(30149..30988)
                     /gene="folP"
                     /locus_tag="ACZPB4_05210"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004156 - dihydropteroate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HIR1097654.1"
                     /translation="MLDKTLNIRGTLTSLATPLVMGILNITPDSFYAGSRKQTETAIE
                     DRIREILSEGGDWIDIGGYSSRPDAAEVTPEEEMRRLEFALHILNKHYPDIPVSVDTF
                     RAGIARRCVEEYGVAVINDISGGELDADMFQTVADLKVPYIMMHMRGTPQTMQRHTDY
                     PDMMEEIMLYFSRKVRQLRLLGVNDIILDPGFGFSKTLEQNYQLMSHLKEFSIFELPL
                     LVGVSRKSMIYKLLGGTPADSLNGTTVLNTYALLNGANILRVHDVREAVEAIRVIGQM
                     TNK"
     gene            31118..32401
                     /locus_tag="ACZPB4_05215"
     CDS             31118..32401
                     /locus_tag="ACZPB4_05215"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009016809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HIR1097655.1"
                     /translation="MSIIDLYDLFIHNPQITTDSRNCPKGSIFFALKGDKFDGNQYAG
                     KALASGCVYAVIDNPDYYIGERTILVDNVLKTLQQLAHHHRKVLGLPIIGITGTNGKT
                     TTKELLAAVLSTKFNLLYTEGNFNNHIGVPLTLLRLTHDHEMAVIEMGASHPGDIKEL
                     VDIVHPNYGIITNVGRAHLEGFGSFEGVIRTKGELYDYIRRSKGKIFIKKENEYLQSI
                     AKGIEQITYGNGDDAFASGQVVSCDPFLVFNWKQQGKLHTVETHMIGSYNLDNVLAAV
                     AVGRFFKIPAERISRAIAAYEPTNNRSQFKKTDNNELIIDAYNANPSSMKVALDNFIT
                     MPVQPKAIILGDMRELGPTSDELHAEVVEQIKKGQFDKVFLCGEHFSKVGKEFSPFAT
                     TEAMVEELRKQPLKGYHILIKGSHSMGLEKLADIL"
     gene            complement(32396..34582)
                     /locus_tag="ACZPB4_05220"
     CDS             complement(32396..34582)
                     /locus_tag="ACZPB4_05220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2339 domain-containing protein"
                     /protein_id="HIR1097656.1"
                     /translation="MEYTLLILLLLIMIWINLRNKISKSQEKTEELSKEIAALRRRLE
                     NSSEVADEIKEPEPETLKEPEVFVQPEPVKAIVEPARNLQPQKVRKPVNYEKYIGENL
                     FGKIGILILVLGMGLFVKYAIDKEWINETLRTILGFGMGGLLLFVAWRLKDSYRTFSS
                     LLAGGAFAIFYVTVAIAYHYYGLFSQTVAFILLVLFTGFMSSLSILYNRRELAIIALV
                     GGFIAPFLVGSGDGSYWVLFTYVMILDLGMFGLSIYKKWGELPVICFALTWIVFAGYT
                     YAADLDLMGSVQLTHLLIFSIAFYLIFLLSVASIVRINIRGINQYLLGVIGLNNFVFL
                     FFALCLLQNMELEQNYKGLVTLFVAAINFALFFWIKRKGEPFTFLMHTLLGIALTFVS
                     VTIPIQLEGTFITLFWASEVMIILWFYSRFRLRVYEIFVWVLPVLTLGSYGMDVFHGC
                     MKARYGDSSLFINGLFATGIFTGLSYWVDAWLVRPTRISTKGPLLTGCVVLYIAFVFD
                     FYSYVDPSIVSFSYIETFTVAVLFAANVLLGKSYLPVSRNAGGYGLLLGLSLSLFGGM
                     SLWVGYDDLFIPRFLLWVSLLLIGGHIFVLGRYYYKSFDAREKRTHGMTLYICLLSTI
                     LLAVGTNNLLNQLGLPDELSAGFSISLSLAGFMQMAVGMRLHLKVVRMISLATFSIVL
                     LKLVMVDLWLLPTIGKVVVFIILGVILLILSFLYQKLKTVLFDDSL"
     gene            complement(34861..37671)
                     /locus_tag="ACZPB4_05225"
     CDS             complement(34861..37671)
                     /locus_tag="ACZPB4_05225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6383 domain-containing protein"
                     /protein_id="HIR1097657.1"
                     /translation="MNKKFSTLVAGLALCTAFTANAKVENGKVYQLTNEDGKYLSVTE
                     SYTKTDSLILADAPTADIKNTDYQKSLWKVTYRFVSLANTWAYTLTNSATGRVLTLDK
                     QAEWNFKNEGAFIAPENVTAVTLSAQLDNKTVVSIIAKDDVEAERTDIVTLEKGTAVS
                     ASAINFTVAAPAKINMTADLLNNKYGSPFALTFDKNLDGNPLAGKELFATDIDGLDGY
                     VTLQDRTTGKYLVVDSTSWSSNLSSEKFWKLTVDAQPKDEAAAADKATGVTAGTILEN
                     GRAKELYAFKVVLDPSDNSKMILYPYATPVYKGANDTEKKSKMCYDMEVAANGEMIAF
                     GNFAGTEKLTIWTKDAAKCTFAEVKLPTTLDPEYTYFVKDMNNAKSDEDHSANKNKGK
                     YYVFSFCENGTVHAGAVTEVPTALWYLTETNNLANMWNTNSTRGGAIIRVIDDAKAIY
                     SFGTDTVQLVKGPKVEDAQELAYKKVSKEDLVNGALSFRLKSDLLENLYVTVKDGKLY
                     VAAGELASAYRFKVEEVELDEANSTVAESNGVKVYKYNVTDRLGKATLCSKNENGTDY
                     YLMGEPDVENGVYPVTLSFLSTGVENEYKLVSSSEYTEEYGYYGSAISALAGSGMLYT
                     ASWCNTENTTFEFAKKDAPTYATLNIGHVQITSYTEDDNKMIASQKDGFAVLKAEGQS
                     ILKSDVYTHDSLTLWLDTACLTFEETMPLYYLSTNAFAEEGVKTRNYLMNTLDSAEVK
                     GYAYEAAGAEAVRAAFIAGSVCGIDSIAIKGDTINAMNLNPAAVAFEVAAEYSDEAYK
                     ILSVQEYLNPAYDEEAAEEQGEEYDVEKYLPRNAYLAHLNNVVYWTTDPEQAEVFKVM
                     TTSTPTSNDKIAAESAISVIANDGTVTIQGAAGKSVVISNILGKVVAETVLSSDNATI
                     AVPAGIVAVAVEGEAAVKVVVK"
     gene            38124..39020
                     /locus_tag="ACZPB4_05230"
     CDS             38124..39020
                     /locus_tag="ACZPB4_05230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PfkB family carbohydrate kinase"
                     /protein_id="HIR1097658.1"
                     /translation="MNTHELCCVGHITLDKVVTPKNTVHMPGGTSFYFSHAIKHFDDI
                     DYTLVTALAESEMKTVEELRAEGIDVAVMPSKHTVYFENIYGENQDNRTQRVLAKADP
                     FTVEYLENINSKIFHLGSLLADDFSLEVVKYLAGKGLVSIDSQGYLREVRDKDVFAVD
                     WPEKKEVLKYVHFLKANEHEMEVLTGYTDAVNAGKVIYDWGVKEVLLTFGSMGSIIYD
                     GSTFHKIPAYIPKEVVNATGAGDTYMTGYLYKRAKGASIEEAGRFAAAMTTLKIEGIG
                     PFNGTKEDVLRCLETAEQRMPE"
     gene            complement(39084..40322)
                     /locus_tag="ACZPB4_05235"
     CDS             complement(39084..40322)
                     /locus_tag="ACZPB4_05235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HIR1097659.1"
                     /translation="MNEKMNATLGNAFPKERIRYAMLSFFLAQGLCFSSWASRIPDVK
                     DIFEVNYAFYWGLVLFLIPVGKFVAIPLAGYLVSKLGSRIMAQVSVLGYALALFAIGT
                     AHNIYLLGVYLFCFGVFWNLCDISLNTQGIGIERLYGRTIMASFHGGWSLAACLGALI
                     GFIMIVSGVTPFWHFTLIALLIGVTVLVSRKYLQEDVAVESPEEEKEAEKKEAPALLS
                     FIRKPEMLLIQLGIVGLFALVVESAMFDWSGLYFESVLQVPKSLQIGFLVFMVMMTVG
                     RFLTNSAYSVLGKQKVLQLAGFFILAGFFISAMLGGMFESMTVKVIVNSLGFMLVGLG
                     ISCMVPTIYSLVGAKSRTPVGIALTILSSISFIGSLIAPLLIGAISQAFNMKYAYIVV
                     GLLGLCILLMTTFCKAFKNN"
     gene            complement(40491..42758)
                     /locus_tag="ACZPB4_05240"
     CDS             complement(40491..42758)
                     /locus_tag="ACZPB4_05240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter domain-containing
                     protein"
                     /protein_id="HIR1097660.1"
                     /translation="MSEIAPLISDLAVILIAAGIITLIFKCLKQPVVLGYIVAGILAG
                     PAVPYIPTVSDPTNIKIWADIGVIFLLFAMGLEFSFKKLMTVGGTAVIASITIVSGMM
                     FLGYTAGNALGFSHLSSIFLGGMLSMSSTAIVFKAFDDMGLRGQKFTGVVLGVLVVED
                     LVAVVLMVLLSTLAVSKQVEGMEMLESILKLGAFLIFWSLLGIYLIPSFLKKIKPFLN
                     DETLLIIALGFCLGMVMIAAKAGFSSALGAFVMGSLLAETIEAEKIEKLVKPVKDLFA
                     AIFFVSVGMMIQPDLLIEYLVPICILTILVIIGQIFFGSLGVLLSGQPLKIALQSGFS
                     LTQIGEFAFIIASLGVSLKVTDDYLYPVIVAVSVVTTFLTPYMIRMATPVYQLIDNYL
                     PSSIKLMLNRYSSGSNTVKHKSTWNKLLKSMLLDVILYTVLTIFSIIIFFTYVNPIIR
                     ENILGFKGALLSLSIILAIILPFLWAIIMKKNHSPEFLKLWNDSKFNRGPLVSLIAIK
                     LLLCASILMPVIVHIFNVASGVGFIITLLILLMIILSKKLKKRSLSIEKRFIDNFNGK
                     TTDSNIGSPLTDNIFKSLPFNDLHLMDFVVGQESSIVGRSLKEINFRQKYGINIVSII
                     RGERQINIPRGEERLYPFDKIIIVGTDEELDLFQEIIQKQDKEYRDQLAQSFNNNIKI
                     EQFNIEPDSPLIGRSIQQSDIRDKNACLILGIERDGKSMMNPPSQTVFKENDNVWVAG
                     EYRQIVQLSEGLSYN"
     gene            complement(42988..43063)
                     /locus_tag="ACZPB4_05245"
     tRNA            complement(42988..43063)
                     /locus_tag="ACZPB4_05245"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(43028..43030),aa:Lys,seq:ttt)
     gene            complement(43133..44290)
                     /locus_tag="ACZPB4_05250"
     CDS             complement(43133..44290)
                     /locus_tag="ACZPB4_05250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HIR1097661.1"
                     /translation="MNPLFDKPFTFDRVIRIVFGILVISGIIYLIALLRNALLPFLIA
                     WLLAYMMQPFVKFFQYKLCFKSRILSIMAVLVTLGLLITLLVVMVIPSIAAEADKTLE
                     LIRTHDPGEGHVPLIPHSWMEYLESNVNFAQIMELLSKENLLKAVKQIAPQLWSILSN
                     TFSILFSITIVFVILLYFIFILLDYEKIANGWIDLIPERYRPFLQGLAEDVEYSMNRY
                     FRGQSLIALSVGVLLAIGFKIINFPLAVTLGLFIGVLNLIPYMQAIGIIPMILLSLLR
                     SAETGENFWLIFGMAILVLGIVQCIQDLYLTPRIMGKAMGLNPAIILLSLSIWGTILG
                     FIGLIIALPLTTLCLSYYKRFILHEYNELDSRSLAHQPKQEEINSDLIAKK"
     gene            44349..>45684
                     /gene="dacB"
                     /locus_tag="ACZPB4_05255"
     CDS             44349..>45684
                     /gene="dacB"
                     /locus_tag="ACZPB4_05255"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004175 - endopeptidase activity [Evidence
                     IEA];
                     GO_function: GO:0009002 - serine-type D-Ala-D-Ala
                     carboxypeptidase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine
                     carboxypeptidase/D-alanyl-D-alanine endopeptidase"
                     /protein_id="HIR1097662.1"
                     /translation="MIRKISFFFLISCLYLSVGAQTPQPIKQFLRKPYMEGASFSLIV
                     KEVNSGETVFAYDTIRQLTPASVMKTVTTATALEILGEDYRFPTALEYDGSIENGLLK
                     GNLYIKGSGDPSLGSAHFAPDHKRFLQEWISALKKVGIHKIQGAVIADESIFDTEGTS
                     LKWVGEDMGSYYGAGSYGLCVFDNLYKLGLQTGAPGTRPKLKGTEPELSGIHFHNYLT
                     AQQVSSDSSFIVGAPFATDRYLYGIVPANREWYPLKGDIPDPALFLADYLTRQLEHEG
                     ITVGESPSCFRILREAGRWQPGKRTEIVTTYSPTLREIVEVTNHVSHNLFADALIKTI
                     GLRYTPRKGEVISSFNRGIQVLRDYWQGKGLDLSCVWMYDGSGLAVTNKLSTAFVADL
                     LIYMKTCSQQHTAFYESLPAAGVEGSVRNFLKGSSLQGKAHLKSGSMSRVKGY"
BASE COUNT        13374 a        11278 c         9238 g        11794 t
ORIGIN      
        1 acagtagcat cgtaggtttc agccacaccc acttcagcgg taccggccac tccgacctcg
       61 gggatatctt gattatgcct accaccggaa cgttgaagct aaaccccgga acggccacga
      121 atcccgatgg cggttaccgt tcccgtttct cgcatggcac cgagatatcc cgtcccggat
      181 actacgaggt gatgctcacc gattatggcg taaaggcaca actgaccacc acccaacggg
      241 tcggcatcca caaatacaca taccctacga acagtgagaa ccaacgcatt atccttgata
      301 tgattcacgg gatctataac tatgacggca aagttctttg gaccaatatt cgcgtagaga
      361 acgatacgct ggtaaccggc tatcgtatca caaacggttg ggcacgtacc aactatactt
      421 atttcgccat gtctttctcc aaaccgatca cgcattacgg atgcgaagag aaagcgaaag
      481 ttaattatcg gggcggttat gccaagttca atatgaaaga gaacttcccg aatatcggag
      541 gacgtaagat cgtcgcttat tttgatttcg atccgaaaac gtctgatgag ttggaagtga
      601 aagtcgccct ttccggagtc agcaccgagg gagccttgaa aaatctacgt gccgaggctt
      661 ccggtgcgga cttcgaccaa ttagccgcca aagcctccga tacttggaat aaagcgctct
      721 ccgtcatcga cgcgaaagga agcgatgatc aattggctat gctttacacc tccttgtatc
      781 acacgatgat caatccttgc gtatatacgg acgttgacgg tcaataccgc ggactcgacc
      841 ataatatcca tcaagcggac ggattcacga actatacggt tttttccgta tgggatacct
      901 atcgtgccct acatcccctg ttcaatatca tcaaccgaca agttaacacg gatatcgcca
      961 aatctatgtt gaaacattgc gagcaaagcg ttcatcatgc cttgccgatc tggagccata
     1021 tggcaaacga gaactggtgc atgatcggtt atcattccgt ctctgtcttg gcagatgcta
     1081 tcgccaaagg attaccgatc gataaagacg ccgcgttaaa agcgatgatc agcagctcta
     1141 cgattccgta ttatgaggga accaaagagt ttatggaatt aggttatgtt cctttagatc
     1201 gcaacggtag cgcaggctcc ttgactttgg agtatgctta tgatgattgg acaatctata
     1261 atacagcttt attagtggga aaccgatccg tggccgatac ctataaaaag cgtgcgtcca
     1321 attacgcgaa tgtattcgat acctcgatcg gatatgcccg tccccgttat acgaatggta
     1381 aattcaaaga ggacttcagt ttgttaagca cgcacggtga agggtttatc gagggaaatg
     1441 ccttgaatta ttccttctat gtccctcaag atgtcaatgg tatgattcag ttgatgggag
     1501 gcgagcaagc attcatcact aaaatggatt ccttattcac gatgcatctt cccgatgagt
     1561 tctttgccga gaccgaagac gtaaccaaag aaggattact aggaggttat gtacacggca
     1621 acgaacccag ccatcacatc ccattcttat acgcatggac cagccagcct tggaaaaccc
     1681 aattctggca acgcgagatc atgaataaga tgtatcgcaa caatatcgac ggcctttgcg
     1741 gtaacgacga ctgcggccag atgtccgctt ggtatatcct ttccgccatg ggattctatc
     1801 cggtttgccc gggtacggat caatacgtat taggcgctcc ttaccttccc tatatgaagg
     1861 tccgcttgga gaatggtaag actttcgagg taaaagccaa taaagtcagc gacaagaacc
     1921 gttatgtaaa agcggtaaag ctaaacggga aaccctatac caaaggatac atcacgcagg
     1981 atgacatcat gaacggtgga acgctcactt tcgagatgac ttccagcccg aacaaaaagc
     2041 gattgttcaa cggagaggat cgcccttatt cactgacgga ttaacccatt ttatcagaaa
     2101 aaacagacaa gactcatgaa gtataaacaa ttaatcagcg gtgctttcct gctgtggact
     2161 tgcatcgctt gctccggcaa aaaggaacag gcggctacag tagcggaagc cacctcaaat
     2221 ccttgggata attattacat cggaaagatc gatttcaaga atctttcccc cgaggctaag
     2281 ggctcggcga tctatgccgc cgttatccct gatccggaag cttatattac caagcacgcc
     2341 cgcaaggtcg tagagacgct ttatttcact ccggaagata gtatcccggg catcgaggag
     2401 atccactata cattaaagga atacgacggg gtatccgcaa aagacggagc gcccccttcc
     2461 atcagtatcg tatacagcac gaaatggatc gagaaaagtt ttgccaataa tgacaccgcg
     2521 aaagtggatt acgagacccg tggcgtatta taccatgagc tgacgcatgg tttccaattg
     2581 gagcctcaag gcataggtag ctatgggact aataagactt tctgggctat gatagaaggt
     2641 gtggcggatg ccgtaagata cctgaacggc ggttttacct tggaagatcg tcccaaaggc
     2701 ggccattata tggatggtta ccgcacgaca ggcttcttcc tcgcatggct tacgcaaacc
     2761 aagagcccgg atttcctgcg gaagttcaac cgaagcacat tagaggttat tccttggtcg
     2821 ttcgatggtg gcgtgaaata tgcgctcggc aatgattacg acatagactc cttatggaaa
     2881 gaatatatgg caacgatggg agatgaagcg tagccccggc aaaggctacg accaacggcg
     2941 gtaacactca acaagttacc gccgttcttt tatagtatca ctcccgacct tccgccaata
     3001 ggcattataa ggtcgcaaca atgcccatcg taagctcctt atactgccca tcctaacaac
     3061 cttacaatgg gcattgttac attattcccc taaaacacct tccttatttg catttccgta
     3121 aacatatatc tacttttgcg aaaaagtaaa tatggaactt tatacccgaa tcctgttgcc
     3181 gaaagcacga ttctctttct cgtatgagga ccgggtcgtg atgatgggct cctgcttcgc
     3241 cgagaatatc gggcggaagc tggaagagaa taagttctcc gtagatataa acccattcgg
     3301 tactctgtat aacccggctt ccgtagcgga aggattgagg atgctgctac gcccggagcg
     3361 tttcactccc ggcgatttat tccagcatga gggcatatac catagtttta cccatcatag
     3421 ccgtttctcc gctccctcgg aagaagaatg cctaggccat ataaacagcc gcttatccga
     3481 atcctccgat ttcctgcgaa aagcgacccg gttggtaatc acgttgggaa ccgctttcgt
     3541 ctaccgcctc aagagcgacg ggcgaatcgt gtcgaattgc cataagctac cggaaaagat
     3601 gttcgaccgg caacgattat ccacgcaaga gatcgtcgag gactggaaac ctctgttact
     3661 agccctttgg gaacaaaatc ccgccttgaa aatcttattt accgtaagtc cgatccgcca
     3721 ctggaaagac ggggcgcacg agaaccaact cagcaaagct accctattgc tagccacgga
     3781 cgccttacag aaagattatc ccgaccgaat cgcctacttc cccgcttatg agatccttat
     3841 ggacgagctc cgggattatc gtttctatgc ggacgatatg ctccatccct ccccattggc
     3901 cattgattat atttggcaac gttttatcga aaatttctta tccacagaca cttcggcaat
     3961 ccttaaagaa tggggtgata ttcaaaaagc tattaaccat aagccctttc aaccggatag
     4021 cgaggcctat aagcggttta tccttcaaac tttgttaaag atggaacgaa ttagcgagaa
     4081 aattccttcc tttgatatca gaaaagagat cgaaatagta aagtctaaac taaaataaaa
     4141 gaatggaata cgcaattaaa gaaatagcaa gagttatcgg tgctaaaaca aaccaattgc
     4201 ttgacgatac ggtcagtttg ttgttgactg acagccgtcg tctctccttc ccggaacaaa
     4261 gcctcttctt cgccttgaaa accaagacga acgacggaca tagatatata caggaactct
     4321 ataaacttcg tgttcgcaac ttcgtggtaa gcgatatgct accggagttc gagagcatga
     4381 aggacgcgaa cttcctgatc gtaaaagata cgttacgagc tttacaaaag ctggcgactc
     4441 accacaggaa gcaattcaac atccccgtga tcggcatcac cggtagcaac ggaaagacga
     4501 tcgtaaagga attcctctat caactgctgc ataacgagtt caacatcgta cgttcgcccc
     4561 ggagctacaa ctcccagttg ggggttcctc tctcggtatg gcagatgagc gagaaaaata
     4621 cactgggcat cttcgaggcc ggtatctcac aaccggacga gatggaacgc ctgcaaccca
     4681 tcatcgcccc cacgatcggt atcatcacga atatcgggga ggctcatcaa gagaatttcc
     4741 tctcctccaa tcagaaatgt atggagaagc tgacgctttt caatgattgc gaagccatta
     4801 tttatgatgg ggatgattta tttatcgcca attgtatcga atcggcttgc ctttctcata
     4861 aagcgatcgc gtggagccgt acggactccg aggctccttt gtttatcgag tctatcgata
     4921 agaaagagtt tgagacgatc attcactgta ctttactggg cttcaaccgg gtcgttacca
     4981 ttccgttcac ggacgacgct tctatcgaga acgtgatcca ttgtatggcg gttatgcttt
     5041 acctaaaacc caccagcgta aacgacgtaa cgaaattctt acatcttgag ccggtggcta
     5101 tgcgattgga cgtaaagcaa ggtatcaaca attgcctatt gataaatgat acctataact
     5161 cggatatcaa ctccttggat atcgcactcg atttccaaca aagccgccgg gtaggcaagc
     5221 aattaaagag cactttaatc ctctccgata tccttcaatc gggcaccttg ccgaaatctc
     5281 tatataagaa ggtcgccgat ttggttcgcc gtaagaagat agatcgtatc gtcggtatcg
     5341 gccgcgactt aaaggaatat gcttccgtct tcgagatcga gaaggagttt tacacgacca
     5401 ccgaggaatt tatcaagtct ccttccttca agaaattcaa ggatgagttg atcttgatta
     5461 aaggttcccg ccatttccat ttcgagcaga tctccgagtt gttggagaaa aaggtgcatg
     5521 agacgatcct agaggtaaat ctggacgcga tcgtacacaa cttcaatcag tatcgttcca
     5581 agctaaagcc ggagactaag atggtttgta tggtaaaagc tttcggttat ggagccggct
     5641 cttacgagtt ggcgaagacc cttcaagaac atcgttgcga ctatctggcc gtggcggtag
     5701 ccgacgaggg agccgaattg cgtaaagaag gtatctcgat ccctattatc gtcatgaatc
     5761 cggagttcag cagtttcaat gtcttgttcg agaaccatct ggaaccggaa gtctatagct
     5821 tccgcctatt ggatgccatg atccgggaga ccgagcgcag aggcatcacc tcttacccta
     5881 tccatatcaa gatcgatacc ggcatgcatc gcctagggtt tcaaccggag gatgtcccgg
     5941 cgatctgtga acgcttgaga gcacaatccg gggttatcgc ccgttcggtc ttctctcatt
     6001 tagccggaag cgactcgtac gtcttcgatg attttaccca tcaacaattg gataaattca
     6061 ccaaagccgc aggggaatta gaaaacgggt tagagtataa ggtaatcaaa catatcctaa
     6121 actccgcagg aatcgagcgt ttcgccgctt atcaaatgga tatggtacgt ttaggtatcg
     6181 gtttatatgg agtaagcgca tccggacaaa aaggcttacg gaacgtcagc accttgaaga
     6241 cgacgatcct gcaaatacaa aacgtacccg caggggattc gatcggttat agccgtatga
     6301 gttatgtgaa acgtgattcc cggatcgcta tcatcccgat cggatacgcc gacggattgg
     6361 atcgccactt cagcaacgga ggcggggagg tcttgatcaa tggacaacgc tgcccgatta
     6421 tcggcaacat ctgcatggac gcttgcatga tcgacgtcac cgacatccat gcgcaagaag
     6481 gcgacgccgt aattattttc ggcgacgaac taccggtgag cgaactttcg gataaactga
     6541 aaacaatccc ttatgagata ttaacctcta tctcgcctcg ggtaaagagg gtttatttcc
     6601 gggaataaga agtaaccgcc aacaaagaat gactctacct tgttttaata tcaaggcaca
     6661 tattcaaatg tcaggctatg atattcattt gcgtatgttg cacattttgt gtatgtttgt
     6721 gccgtaatta ataaacaaga ggtatgagtc ataatttatt gaaaggcaag agaggcatta
     6781 tcttcggtgc gctgaacgat atgtctatcg cctggaaagt ggcagaaaga gccgtagagg
     6841 aaggtgcgac tatcacgtta agcaatacgc ctatcgctgt tcgtatgggt caggtagatg
     6901 ctttggcgga gaagttgaac gcgcaggtaa tcccggcgga cgcaaccagc gtagaggatc
     6961 tggagaccgt attcgcgaag tcagtggaaa tattaggtgg taaaatagat ttcgttttac
     7021 attctatcgg tatgagcccg aacgtacgca agaaacgtac gtacgatgat ctggactatg
     7081 gaatgctgga aaagacgttg gatatctctg ctatctcttt ccacaagatg ctacaggtag
     7141 ccaagaaaca agacgctatc gccgagaatg gttccgtagt ggcattaagt tatgtggccg
     7201 cccagcgcac gttcttcgga tacaacgata tggcggacgc taagagcctg ctggaatcta
     7261 tcgcccgtag tttcggttac atctatggcc gtgagaaagg cgtacgtgtg aacacgatct
     7321 cccaatcccc gacaatgaca accgcaggta gtggcgtgaa gggaatggaa cacttgatgg
     7381 acttttctaa caaaatgagt ccactgggta acgccaacgc tgacgaatgt gcggactatt
     7441 gcgtaatgat gttctccgac tttacccgca aggtaacgat gcagaaccta taccacgacg
     7501 gtggtttctc aagcatgggt atgagcctcc gggccatgaa ccaatacagt aagggattag
     7561 aggaatatac agacgagaac ggacacgtca tttacggcta atatgttagt aaaaatatat
     7621 ccggagaatc cgaatcaaaa agaaatagac aaggtcgtca aagtcctgca ggacggcggc
     7681 cttgtcgttt atcctaccga cacggtttac gcgatcggtt gcgatgcgtt aaacgtgcgt
     7741 gcggtagaga aaatatgtca gatgaaaggg gttaatccac agaaaagcaa cctgtctatc
     7801 atctgctacg acctgtctaa tcttagtgaa tacgccaagg taagcaacgc cgctttcaaa
     7861 ctgatgaaga aacatctacc cggtcctttc acctttatct tacccaccag cagcgagctt
     7921 ccaaagattt acaagaaccg gaaagaagtc ggaatccgtg taccggacaa taacattacc
     7981 cgtacattgg tacaatcctt gggaaatcca atcctaacca tgtccatccg tgacgaggat
     8041 gaggtgatcg aatatacgac agatccggaa ttgatacacg agaaatacga gcatcaagtg
     8101 gatatcgtaa tcgacggcgg tttcggagga ttggaagcct ctacggttat agattgcacg
     8161 acggataatt tcgagatcgt acgtcaaggc aaaggagaat tgtagctatc caccacgatt
     8221 tgtattcgct cctccggcag attagcaggg aactccaagc ttatttcttg ttggtcaccc
     8281 ggcattagcg taatatagtt atccgaataa tgtaccggta agattcgttt gcctgtctcc
     8341 ttatcaaaga ccttgatacg gttgaagaac gagatctgcg aatcagcgct cagacggact
     8401 gtacctacga aattcgatcc ttccttcttg atctcggtct tgattcccgg tcttgacttc
     8461 ggaagttgag ataagctggt gtagtctttc ggctcggttg tcagccaata aatattgggg
     8521 acatccgcat tcaaagccag ccgtaagaaa taagcgcctt tgatcccttc cggaacgggg
     8581 atatccaata attcctgtac cgtattcgcc ttagcgctcg ctctcgtctc tttctcccaa
     8641 agcagtttgc cttccagatt atagatacgg gctacaatcg ataaatccgt ataatctttc
     8701 agggtcgtat tcaacaatcc cgccttacgg gttaccgggt tataataggc atgtaagggc
     8761 tcacagcctt tccgggttcc gtacaaggaa gcatttacat cgagagacca atcatacatt
     8821 tgcccccgca aggatgtcca tggattctgg gttttccaga tcaagatacc cgtataccaa
     8881 tcccacatat gagaggccca gccttccata aaactacgat attggtcata gttcacgact
     8941 tgggcatact tacaataggt ctcgatatcc ttcacctccc catatcgctc cagatgatcg
     9001 ccatagccca gatccttatg ataccgccac gtataattac gagtaaaacc tttccttggg
     9061 aaaccggcca aatcctgttc cgtcatcatc tcccgaatac tctcgacctc cggggaacca
     9121 accgatccgg cttccggatt aaacggatgc gaacggaagc taaagaacca ttccggctct
     9181 tgtataccgt aaggaccatc cccattatcc cccaaataat tccgggtaaa caacgtatct
     9241 gtagagaaac tcacgaaaag acgttccgga tctaaccggg ggaaaacctc ctttctcaaa
     9301 cattgatcga tatctttagc taaaggccat tcattcgccc cacaccagaa acaaagactc
     9361 ggatggttac ggatcatttt cacttgatct tccacggagg cgataaataa atcatgatta
     9421 tcgggatatt cccaacgacg ctctcgggaa tccatcttgg tcgggtcctc ccaagcgcca
     9481 ttgcaatcac cactgcccca cagatcttga aagactaaga taccgaactc atcacaggcg
     9541 ttatagaatt ccggccgttc caccaacgca cctccccata cacggatcat acgcagattc
     9601 atttccgcat ggaaacgtac ctcatcccga taacgttccg gagaaagacg aagcagccaa
     9661 tcggaattaa tatagttacc acctgtgacg tatattttct gtccgttcac gaagaaacgg
     9721 cgtcccccgt tatccgggca tttatcggaa gtaatctccc ggataccata acgcaaccgt
     9781 tcccggtcac tcacttgatt cccgatctca aaagagaggt tcatatcata taaaggctgc
     9841 tcgccgatac cgttaggcca ccataaacga ggattcttta ccgctaaagg attcaaggat
     9901 accgttttct tctcgaatgg cgataaagta accggctggg ttaagcgggt tccgttcgtc
     9961 tcacaaacca atagcccctt taaggaagtg ctcccggtat tctctagctc gacagaggta
    10021 ttcacaaaag cctccttttg agttttcgtt tccggatcac gtacgccggg taccttggtc
    10081 acgacataag gagaggagag gcataccggc ccggttgtcg taatagatac ctcatcccaa
    10141 atacccgtat tccggtctcg tacaggttgt atccagtccc aacccggcgt atattgcatc
    10201 gtattattcc gggcgatctg cccatcaccc ccttgtccgc catttggatt tccgacatgt
    10261 gtaggtggat aaaccaatac cgctaataca ttcggggcat ccgtacgaag ataaggagtt
    10321 atattaaacg tcttcctcaa gaacataccc tcatgggtat tccggttgat ccgcttacca
    10381 tttaaaaaga tttccgcctt ataattgatt ccccggaaat tcaaccagac attacgcccc
    10441 tctggtaaag catcgatagt aaactgacgg gtaaaccaat acgtatagaa atcattgccg
    10501 acttcatgta tatcgggaat caaattgtta ttcaacccaa actcaggggc cggatacaaa
    10561 ccattctcca aaagcgttgt caacaccgta cccggtacac gagccggtaa ccatcctgtt
    10621 ttatccaaag gcaccgcgct caaccggttc ccatccattt tcacctcatt cgctttccgg
    10681 gcataccaat ctgagtgaat caaggttttc tctcccggtt ccgggatcac caacaaggct
    10741 tgcccctccg cggatacggg ctttgaccag caagccaggc aaagccaaca aaataaataa
    10801 atacatctgt tcatcatata atcttagatt tatccttcta aagtagtaca aaattcagaa
    10861 gggcctcttc gcaaactcga agaagccctt tcattacata ttatttaaca ataagaccta
    10921 ttaatgccga ttagaaatta cctacaccag ctttgtccca ccatacatga gtaccacctt
    10981 tatcaccaga gatcgaaccc gtattctctt gattcagcag ctcgatgcct ttctgtaatt
    11041 ccgcattatt ggtgttaatt tccgtatctg agtagatcaa gcgacgaact tgttcgttag
    11101 tattgatatc accgttactc aagtttacac gattcgggaa taatttagga tagcctgtac
    11161 gacggtattc agcccaagcc tcacaagaca atgggaagtt agcgatccat ttctgagtaa
    11221 tgatacgttg caacttctcc tccttactag caccttcgtc ccatttaaca cctagtgtat
    11281 tcatcgcctt tatactattt tccgccttaa ccgggtcaac aaagtcaatc tgtccactgg
    11341 ttccattgag ataagcgtct atttccgcat ctgagataga agttacacct gcaatactgc
    11401 ccttataagc caattcgttc ttgatagaaa tacgaatgcc ctcctcatat agatctttag
    11461 cgctacctcc catgctccag ccacgtaaag caccttcagc acgtaaaaaa taaccctcag
    11521 caactttcat gacagggaaa gcggtcgtat aagtgcaaat cactttagag aaattacccc
    11581 attgatttgg cttagaaggt aagttacatc cgccgcgaac accaagatac tttgtcccct
    11641 cctcaattgt cgagccatct tcacaagtaa cagccgcttg attcttggtc acatacaaag
    11701 gtaaacgagg atctttgaaa ccttccaaca tcgtgattaa gctagcattc attccacaat
    11761 caccccactc aaacatacga gtcaactcat tgctcaaacc ttggttgatc aagatatcac
    11821 gatcagcgga agtcaatacg cctccttgaa cggcttcctc cgctttttgc ttcgccaatg
    11881 tagggttcac ctttacgata cgcatagcca aacgtagttt caattgatta gcgaccttct
    11941 tccacaaagc gatatcacca ttacaccaat agtcaaatgc ttgcatatcc gcaacagatg
    12001 cagttccctt aaatccagcg atcgcttcat ccaccaaagt aaacaaagca ttgtagacac
    12061 tttcctgagt atcataagag aaagaagctc cacccgtagg atcttcgata acagaactat
    12121 aggccactgg gccataggca tccgtcaaca tctggatcgc ataagcttgt acgacacgca
    12181 tcatcgctcc ataatcactt aagccttgct catcacaaga agcaatcaga cgacgggtat
    12241 tgttgaaaat atgaagatat acattctcat acataccacc acagaaacca cggttcaacg
    12301 cataatcaac attaccggaa ccattaaagt tatgtggagt catgaagtag ccgctaaaca
    12361 aatcaatatt taggttgaag caatattgga acaagttctg ctgcggagca tagacataag
    12421 agaatggctc cttaaattgg gcagagaacg gaagttcatc tggatcaacc tcatagggat
    12481 cagtatttaa attttcaaaa ttatctgtac agcccatggt cataacaccg gtagatacta
    12541 ccaaagccga tacagcggca tattttaaaa ttctatttag tttcataaga tatactcaag
    12601 atttagaaat taagttttaa attcaaacca aagctacgag atgttggcaa cgcaaacata
    12661 tccacacctt gccagccatt gcctgtacca gccgctacat ccggatccat aggagcatct
    12721 ttatagaaga agaacaaatt acgtccaatg atagaagccg tcaaattctt attcgctcca
    12781 aataagttac ggaacgtata accaaatgac aactcacgca aacgaacatt agtcgcattg
    12841 taaacatact gagaagtcaa gatattagag ttataacttg tacctccagt cgtcgtgtaa
    12901 tatgctttag gatcaaatga aacaccatca atcacaactt cacctgcatc acgagcggca
    12961 cccgaacgct ctgatacgcc ccaaccatcc aaggtagctt ccgtcattga caagacctta
    13021 ccaccgacct tagcatcaat caagaatgac aatgtaaaat ctttgtaatg gaacgtgtta
    13081 gtccaaccca tgtttacttt tgcgttcata tcaccgacat ataccaaatc cttattatcc
    13141 gtacctccca actcaggagc gccagattca gttttcaccg gcttaccatt atcgtctctc
    13201 ttgaaatcac gaacatataa gtcaccaaaa tgaccacctt cagtcaaaat cactttcgca
    13261 cctgtacaat agctagctaa tgtccaatct ttcaactcat tcgataattc aatgatttta
    13321 ttattattgt aagagaaatt gaaattcgta ctccagctga aattgtccgt aaactgatta
    13381 taccaaccta agctaacctc aaaaccttgg ttttctacgt taccggcatt gatataacgg
    13441 ttcttcaaac cagtttccca aggagcggta atattaaaat attgattctt cgtattggtc
    13501 ttataatacg tcaagtttac attgaaacga ttctggaaga aagttccatc aaaaccaacc
    13561 tctaaagagt tcgtcttctc tggcttcaac gttctaaaag cagcttcttc tggcgggtcg
    13621 atagatcctt ggtcaccaat cgtataacgt ttattggaag catagatagg cacatcgtta
    13681 cccacgatag aataagaagc acgcaattta aataggtcta cattctttcc aaagtccaag
    13741 aatttatcca atagagcact tacaccaaca gacgggtaga aaaaggatac accatccgta
    13801 aacgccaatg aagaagacca gtcgttacga gcgctgacat ccaagaacaa accttcctta
    13861 tatccaaact gagcagtagc gaacacagag ttcaagcgtt tttctttcag agtctctgtg
    13921 gtttgcatcg tataatagtt cttcggggag aagatgttcg gataataagc acccggggtt
    13981 atcacaccgt tatttacttt aaactcctta tcaccccaac cgatcaattc gatgctagat
    14041 gcgcttgtct tcgtaaagct accaccagca gtaacggaca atgaataagt ctcatcccaa
    14101 gttttattat aacttgctaa cgcatcggca tatgtttgct cactgaaagt ccgggtatct
    14161 ttcatggtac ccaataaatt tcgtcccgcg gtactagacg catattcgtt caagatccat
    14221 ttttcatcac cacgttcata acgcaaacgc cccgtaacag aaagaccttc catgatatca
    14281 tatttaacac taccaccaaa ttcataacgg ttacggtccg tgataggagt ctgacgattc
    14341 aacatccagt aaggattgga gaattgctct tgtttcgtat tcgtccagtt atgaacattc
    14401 acgttacgaa ccccgtcata tacttcatag ttactcttgt agtaatccca atcctcacct
    14461 ctcgggaaca ggtaggcacc tgtaatcggg ttattcaaat aaccggcaga aggctgattc
    14521 tcgatatgct gcttgttgta gcgggcactt acatccacat gtactttctt ccacaagtta
    14581 aagccaacct tagccattaa attatgactt aaataatcat tctccggcat aataccattc
    14641 gatgagacat tcgcgtaaga gaaataagaa gaaatattct ccgttccacc agataaagag
    14701 atagagttat tcgttgtata acccggttga tagaatttac gtgcgtaatt cggagatgta
    14761 gctcctaatt tacttcccca gctaaatgtg ccctcgtcac tcataccata attattttgg
    14821 aatttcggca aagacatggc tgattcgacc gtcgtattac tagatacatt aatagcgacc
    14881 ttaccggctt gtgcggattt tgtcgtaatc atgatagcac cattggccgc taccgcacca
    14941 tacaaagcag cggcggaagc acctttcaac aatgtaatct gcgcgatatc atccggattg
    15001 atagtagaca tagcgtcacc accatcacgt tcgccgccat aggccatctt cacctgcgaa
    15061 tcagatacgc tcatcatcat agggacacca tccacaacaa tcaacggttg gttactaccg
    15121 ctaatagact tattaccacg gaataagatc ttagaagaac cacccgcacc cgtagagttc
    15181 ggggtaatct gcaaaccagc gctctttcct tgtaaagagt tgatcatatt cacattctta
    15241 atctcgttca agtccttacc gcctaccgtt tgtgcggaat aagtcaaagt ctttgattca
    15301 cgtttgatac ccatcgctgt tacgacaacc tcatccaaag cctctgcgtc tgaaaccatc
    15361 gtaacatcga ttttcgtacg gccattcact ggctcctcaa tcgttttcat actcaaataa
    15421 gagaatacca aaatagagtt tgcgtcagcc tctaaggtat attttccatc aaaatcagta
    15481 atggtaccgg ttgtagtacc ttttactaac acgttcactc ctgttagtgg ttcatttaga
    15541 tccttgtcaa tgacgacacc actaatcgtt agtttctgtg catatcctgt aacacacaga
    15601 aaaaacgcca ataataagat aaatgacttt ctcatgaaaa atcgtttttg atttaagtga
    15661 ttctacattt gtgctttttt aattttcata ctctttttag agagatcggg ctctcttttc
    15721 tttctttttt agtgcatagg catttactct tttttgttta aagttattat tatattcata
    15781 caaaaatctc tttctattta aaatcaaacg gttatatttt aaataataat aacaacgtag
    15841 tatcattaga actaagtcgt tttcatgttt tgacagacaa atatatatat aataactata
    15901 catacaagtt aaaacgtaac aaaaatcagt atgttcctca ctttttcagg tgtttgcgat
    15961 aacacatagt caaattttca tcatgcctca ataaattaaa tatgttaatt tgatttagtt
    16021 ctaatgaaac taacaacaaa tttcaattaa cataattttc cttcattatc ttcttcctcc
    16081 tataacatcc aatcactatc tgactatcat cttggaataa aattacagct ctatttacaa
    16141 gcttcgaaaa caactcaatc aggaaattaa ccattaactc taatttcttc cacaaatatt
    16201 caatgatttg cacagattat ctctacattt gcgatatata tatattaatg tattgactat
    16261 gaactggacc cagctattat ccggcaagcg ttttgggatg gaagagtatc acgagcggaa
    16321 acatgagaga actgatttcc aacgagatta tgaccgttta attttctcat cccctttccg
    16381 aagactacaa aacaagacac aggtattccc cctgccggga agtatctttg tgcataaccg
    16441 acttacacat agtctggaag tatcctgcgt aggacgttca ttgggtaata acgtagcgaa
    16501 agggcttatc caaaaatatc cggacggcag tatcaacttc ccagagatag gttccatcgt
    16561 atcagccgct tgccttgccc atgatatggg aaaccctcca ttcgggcatt ccggagagag
    16621 agcgatctcc gcttacttct ccgaagggaa tgggcgaaaa ctagaagaga aagtacggaa
    16681 ggaacgggga cgctgggaag acttcgtcca ttttgaaggt aacgcaaacg ccatgcggtt
    16741 gctgacccat cagttcattg gacgcaggaa agggggattt gccttaacat atagcacatt
    16801 agcctctatc atcaaatatc cttacgcatc catctattca ggaaagaaag ggaaattcgg
    16861 ctttttccag tcggaggagg gaagttatct gcaaatcgcc caagagctag ggatcgggca
    16921 taacccggaa gccccggaca aatttcttcg ttacccgtta gtttacttag tagaggcggc
    16981 agacgatatc tgctatcaaa ttatggatat agaagatgct tgcaaactac atatcctgac
    17041 caccgaagag gccatacaac tattattggg atttttcgaa ggagagcggt tggagcatat
    17101 ccgcaaggtc atgcatatgg tagacgatac caatgagcaa atcgcctatc ttcgttcttg
    17161 tattatcggg ctattagtgg atgaatgttc ccgtgtcttt ttagagaacg aggaaagcat
    17221 cctcaatggt acctacagca ctccgttaat cagtaacata tgcgatcaag ccaagcaggc
    17281 ttacgctaat tgctcggcta cagcatacaa gaaaatatat aaggcaaaag aagtactcga
    17341 cattgaatta gccggttatc atattttcag ccatctgatc gacagcttga ccgaggccgt
    17401 gatgaaccaa gagcatgctt acagcaaact gctcttacaa cggataccgg agcaatatga
    17461 cacgaacgct cctactacat atggcaagat acaatgcgta ctcgattata tctccggcat
    17521 gaccgatgta tatgcgctcg atctataccg taaaatcacc ggtatgagcc tgccggccgt
    17581 ttgatgttgt aataatgtgt tagaattctt cccggtactt gctttccatg cgatcatcca
    17641 agatgcttag atagctttta tagcgggact cgctgattag cccatcgtta acggcttgaa
    17701 tgacggcgca gcccggttca tgacggtgcg tgcagttatt gaaacggcat tcttccgagt
    17761 atttaaacaa ctcccggaaa taatgggaga tctcagcgtc cgccatctcg atcgttccaa
    17821 atcctttgat acccggagta tcgatcaaat agcctccccc gggaagggaa atcatctcgg
    17881 aaaaggtggt cgtatgcatt cctttgttat gatattcgga gatatcaccg gtacggagat
    17941 tcacccccgg caccagttta ttgataatcg tggattttcc gacacccgaa tggccggaca
    18001 aaagcgtaat cttatctttt agatccgctt tcaaggcatc caaaccttcc tcggcccggg
    18061 cacatagcgt cgaacaggga taaccaatcg aggtatacaa ctcgattaaa ttctccaacg
    18121 ctctttgatc ctcattatta taacgatcaa tcttattgaa aactaattta acgggaacac
    18181 gataagcctc ggctgtcgcc aagaagcgat cgataaatat cgttgttgtt ataggataat
    18241 tcactgtaac gatcagcatc gcctgatcca aattcgcggc gataatatgc gattgcttcg
    18301 ataagttaga ggcacgacgg atgatatagt tcttacgctc ctcgatctct gtaataaaag
    18361 cggttccttc tttattaata tcgattacga cacggtctcc taccgcgacc ggattggtac
    18421 tctttatgtc tttcagacga aagttaccct tgatcttact ctctatatct cgcccgtctt
    18481 ccgtacggac cgtataccaa ctacctgtgt tttttattac cagtcccctc atgagaattg
    18541 aaaattgaga attgaaaatt gagaattgga ataaggactc aatggggttc cttaattctc
    18601 aattcccaag tttcaacttt caattattta aacggtcatt acttcttttt ctttagcggc
    18661 gtaaagctca tcgatctttt tgataaactt atcatggatt ttctgaacct ctgcctcggc
    18721 atctttctct acgtcctcgg gaaccccatc agacttgatg cttttcttca aagcctcgat
    18781 agcgtcacga cgagcgttac gaacgctgat cttcgcgttc tccgcctcct gcttacattg
    18841 tttcaccaat tgacggcgac gctcctcagt caacggagga atacctaagc ggatcacctc
    18901 accgttattc tccggcgtga tacctaactc agaatccaga atacctttct caatatcgcg
    18961 gatgatcttc ttctcccacg gagtgatcat gatagtccgt gcgtccggaa ccgtcaccgt
    19021 agccacgtta gtaagaggaa caggcgcccc ataatacatt accttcacac aatcgaggat
    19081 tttcggatta gccttaccag cccgaatgtg agacaattgc tcgtccagat actcaatggc
    19141 gaacgtcatc ttctcttccc ctgctttgat caattgtttc gtatctatca taaatatacg
    19201 ttttttgttt gcgaatcttt taattaacaa aagtaataaa gatttccaac ttcgcaaaca
    19261 tataattaaa atactcccta acaaaagatt tataataccg tataaaagct tatcgccctc
    19321 actgtttact taacttaggc gtaaagaata gtaagtaggc tacgcccacg cacaacacca
    19381 gcactgctcc tacttgagaa gccaacatat cggatgccac gcccataaag atcgggaaga
    19441 tcgtgccgcc aaacagtccc ataatcatca aaccggacac ctcattctgc ttattcggca
    19501 tagaaagcag agcttgggcg aaaataatgg gaaagacgtt cgagtttcca aagccgatca
    19561 aggcgataca agcatagatg atctctttcg aatgaaatag cagcaaaccg atcatcgcca
    19621 ataacatcaa gaaaacacta aaggcgaaga atcctttcgg agagactttt cgcaagataa
    19681 aagccccgga gaagcatccc gccgtacgga atatgaaata gaggctcgtg gcgaagcctg
    19741 cgtcggccaa cgtcatgccc agacgttcca tcaagatctt cggggcggtc gtattcgtcc
    19801 ctacatcgat ccccacatgg cacatgatac cgataaagca aagcaggata aaaggcttgc
    19861 ccagcaaagc cagacattcg ccaaaggtgg agggccgccc ctcctctttg gtctcgtgga
    19921 tagtggtagc tcccaatagc aggatagcga tcacggcgat caccatatag accggaaaca
    19981 agacacgcca accgagttcc atcgacggta tcgcttgggt agcaccccac atggcgatat
    20041 aaggcgccaa gaaggaggcg atcgccttca cgaactgacc gaatgtcaaa gaactagcta
    20101 gtttatcccc gcttacgata ttcgataata acgggttcaa ggaagtctgc atcaaagcgt
    20161 tgccgatacc caacagggag aaggatatca acatgaccat atatgcgtcg tcgaagatcg
    20221 ggatcattag cgaaagaaac gttacgatca agctcaataa cacggtcttc ttccgcccga
    20281 tacggttcat caacatcccc gtcgggacgg agaagatcaa gaaccagaag aacacgagcg
    20341 acgggaagat attcgcctcc gaatcactca agcctaaatc cgctttcagg taattagagg
    20401 cgattcccac taagtccacg aatcccatgg cgaagaacgc caacatcacg ggaatcaatt
    20461 tcaaggatga agtcttctcg ctcatggctt ataaatcttt agggtaagca ggccatgcgc
    20521 cactctgcgt acaaacataa gcggctactt ttaccgcttt ctcatgtgcc tcacgtaaag
    20581 gttttccggt taagatcgat gaaataaacg ccccggagaa agaatcgccg gcgcctaccg
    20641 tatctaccac ctgtaccttc ggggtaggaa tcgtagagac ctcctcctcg gaaaagatcg
    20701 tactatactc cgccccggcc gtaagtacca aatagcgcaa accatatttc ttcatgaacc
    20761 agcgacacat atcctctatc gtgccttcca gaccaaacat cgggcgaagc atttccaatt
    20821 cctcatcatt gatcttgaat acgttcgcca attcgagcaa cgattcgatc aattccttcg
    20881 agtagaaatg ctggcggata ttgatatcga agaagcgcaa ggcatgacta ggcatataag
    20941 aaagtaaggt acgaagcgtc tcacgagatt ccgcagcacg ttgcgccaat gttccgaagc
    21001 atacggcgtc cgcacgtttc atcaggtcga tagacgcttg ggtaagcggg atatgatccc
    21061 atgccacacc ttcgatgatc gtataggaag ggatgccgtt ctttagctct accatcacgc
    21121 ttccggtcgg atattccacc gtactgatat aattactatc gataccgttc ttatccaatt
    21181 cctgaataat ctcggttccg aacacgtcgt tgcccacggc actgatcgca taaccttccg
    21241 ctcctaattg ggtagcgtga tacacaaaat tgatcggcgc tccaccggct ttcttcacgt
    21301 ccgggaagac atcccacaat aattcaccaa tgcctactac tacaggttta ctcttttcca
    21361 tgatatattt tgtttttaat tatttgaagg gataaatggt taatgacgta accgtgaacg
    21421 ctcctccctt ggcatgaaag ctaatgcgat tatacggttc ttccgggaag actaggttgg
    21481 tcatgacaaa ctccccattc ccgtcgaaag cctctatgct ggatttatct accagcaaac
    21541 gcaaggtata ttccttagcg gcggagatcg gggccgaggt agccgtggcg aatgtcttgc
    21601 tgaaatccgt gatcccgctg ttacggcgat ccatcgtgaa cgtattatcc agaagattat
    21661 aacgcatctc cacctcctcg cctttcgagt taaacagctg gaagctcatg atatcggccc
    21721 cgttgttctt aaacttgatc tcgatctcat aggttcccgt cggatcggga agtaccggat
    21781 tgacctcatg ggagcggtcc accttgaagg aacctttctt ctgggctttc cctctcaact
    21841 tcaacacctc gggagacggg gtgctgctca agtacgtctg cccgtttttc gtataaagaa
    21901 ccaagtcgcg aggaaccgaa ttcgcactcc ggtattgcaa ggtcggcacg ttattcgcgt
    21961 attcccaatt gctcatccaa gccaaggcga tcttccggtc ctccggggcg ttactccaag
    22021 ttaccgtagc gtaatgatcc ttgccgtaat ccatccattt ggtcaaggcc ggggattcat
    22081 tcacgaactg tttcccatcg aacgcaccta cgaaatattg ggtagcggag ccgccaaacg
    22141 gaccaccggg gttgatatta cagatcaaga cccacttctt caattccgtg cccttcatcg
    22201 gaagctcgat caagtccggg cattcccaaa cgcccgcatg cgctccttgt ccttccccga
    22261 aactgctctc atacgtccag tccttcaaat tgggagaaga atagagttgc atctcctgcc
    22321 ctacggcgag taccatgatc catttattgg attccttatg ccagaagact ttcgggtcac
    22381 ggaaatcacg ttgcgtagaa gtaaggatcg gattccggtc atatttcttg aacgttcggc
    22441 cgttgtccaa gctataggcc atactctgca cttgccggtc gctggccgag gtatagaaag
    22501 ccacgatagc gccagcgcca aaccccgcgg tattatcctt atccaccaca cagctaccgc
    22561 tgaagatcgt acccaaggca tccggggcga tcgccaccgg ttgatgctcc caatgaatca
    22621 agtccttgct gatcgcatgc ccccagtgca tattccccca catcgagcca tacggattgt
    22681 attgatagaa caaatgatac tcaccatcct tgtacaccat gccgttcgga tcattcatcc
    22741 atccccaagc cggcgagaaa tgataggccg gacggaattt ctcccggtta gacgaatcaa
    22801 actgatcgga tagcttcatc tctttccagc aaagagccga ttccggggca agctggaagt
    22861 tgaaggagat atgcttatcc gcataccccg agagatctac cggaacgaaa taatccacct
    22921 tattcaccgc caaacgaaca ttgaaagtcc gtaccacgtc attatcgaca atcatataca
    22981 acttggattc cggcgaggac tcctcgaccg gaagcaacaa atatttggct cgcgcatcca
    23041 cacggacaat gctttgccct tcgcccagat gctttatatc tatagtacgt tctgccgcat
    23101 atccggccaa cggatcgacc gcgctcaata aaatgatacc gacagccata cataaactct
    23161 tcagaagtct ctttgtttgt tgtttcataa acgaacggat taaaggataa tattgtttga
    23221 ttctccgcca aaattaatag gattcttccg gatagaaaaa cacttatccc ttaaaggtga
    23281 ggagatatga catttgtgat aaagatcgta caaatgttat tgatactcgg taggcgtaac
    23341 cccgtagacc gccttgaagc atttggagaa gtaagcgggt gaggagaaac cggttcggta
    23401 agcgacctcg ctcaccgtgt acgcgttctg cctcaacaac tgggtcgcct tattcaagcg
    23461 ataggtacgc aagaactcga cgggtgcggt tccggtaagc tccttgatct tccggtgaag
    23521 gtgcccccgg gataatccca aggtctcgct tagtttctcc acattatatt cggggtccgc
    23581 gtaaacggcc tcgatctgtt ccgcgaactt acgcagaaag gcgtcatcga tgctctccac
    23641 cttctccggc tcggacagaa ggagcttatt atcccgcaac ttctccaaca aacgttcccg
    23701 taacttctgg cgctcttgca ataggtggat aatcttgatc ttcacgtaat ccgtatggaa
    23761 aggcttctgt atataatcgt ccgctccgcc ggtaatcccg aaaatccgtt ggcgctcatc
    23821 ggtcaaggcg gtcaataaga tcaccgggat atggctaaag ggaagttgcg acttgatcat
    23881 ccggcaaagt tcgaaaccat tcatctccgg catcatcaca tcgcttacta ccaatgatat
    23941 ctcctcctct tccaataccc gcaaggcatc tttcccgttc gcggccgtcc gggtcttgaa
    24001 atgagggcta agctcacgtt ccaaaaagca gcgaacctca tcgtcatcct cggtgataag
    24061 tatcgtataa ggataggttt tggaaagcat cttatgggtt tccgaatcgt ccaaccggga
    24121 ggcttcgtag gcttgatggg atacggacgt ttccatcagg tcgctatcct cgaaatgcgc
    24181 ctttcctttc cgcaggcaaa ccgtaaaggt agtcctttgt cccggctcgc tctccacacg
    24241 gatctcccct ccgtgcatat gtatatattc ctttaccaaa tgtaatccga tcccagttcc
    24301 catcgaccga tcctccgtat agaaacggtc aaacaaatgc ggaaggttac cgggttggat
    24361 accacttccc gtatcgataa cctgtataaa aacccgatcc tcctcttctg tcagctctat
    24421 ccgcacgcta cctccctccg gcgtaaactt aaaggcgttc gagagaagat tgacaaatac
    24481 cttctccaac aggtccggat cgatccatag cgtacattgt tttatcgaag aagtgaacgt
    24541 ataggcgatc gcacgtaccg aggccatact gtcaaaataa gatttgatct cgccaacgaa
    24601 agggaccaaa tcgatttccc gtaccgctag tttctcttgc ttgccttcca ccttccggaa
    24661 gtccaagatc tgattgatca cacgcaacaa acggttggcg ttcttctgga tcaacccgag
    24721 atccgaggcg taaggagatt cccgcaagga gattatcaag cgatccaaag gagcgagaat
    24781 caaggtcaag ggcgtacgta cttcgtgaga gacattcgta aagaattgga gtttctgcgc
    24841 cgtcacctct ttcatctccg cattcaagga gattagctta cgattcgcct gcctcatctt
    24901 ccggtttatg taaaaggcat aaatggaaag ggcgataaaa ccaatcatca ataaggagat
    24961 cacccctaaa gagtttcgca ggaaataaaa ccggtcggac aaaccgtcga tacgggaacg
    25021 ctgcgcctcg atacgttgct tatatttctg gagttggtcc gcttgcaaca ataaggtgcg
    25081 ggcagactga tgatctaccg gagccgtacg aagagggata aacttatcca ccggctcccc
    25141 ctgaatgata cgcatagccg tgcgaatcac ttgctcccct cctgtcggat agaggaaaga
    25201 ggcgttgatc cgtccatctt ctacggcttc cagaccggca cccgccacag catccacgcc
    25261 gataatccgc aaatcccgtc ctcggatgga atcccatgcc ataaagtatt cccgagctgc
    25321 tatggccatc atgtcgttat gggcgtaaac gaaatctatc tgctcgggat gctctaactt
    25381 ccgaagctcc atccgggccg tatcgaccag ccattgtcct tctatcttac ggaaagaaag
    25441 atcctccctt tctcgcaagg catcgacaaa acctttatgt cgctcttgcg ccggggaggt
    25501 ttgcgtgagt ccccatatct ctaagataat agcgttcggg ggaagataat tggcggcgta
    25561 attgcctgcc gctagtccga tctcataatt gttcgccccg acaaaagagg tgtattgatc
    25621 ggtatttacc ttgcgatctg taatgatcgt cgggattccg gcacggtacg cttcctcggc
    25681 aactgccgtg atcggctcgg attgataggg ggagatgatc aagacatcca ccttttggcg
    25741 gatcaagtct cgtatttgtt gtatttgtgt ctcgttattg ttttgcgcgt cctttataat
    25801 aatttccata tcatcatagt tagacgcttc gatacgcata tcgttaatca tagcttcccg
    25861 ccaagcatcg tccagcatac attgggagag gccgataacg tgcctcttct gtttccccga
    25921 gctcgtgcaa ccacacaata cgatcaaggt taaccatact agtaaaaagg gatgcttcat
    25981 atacaagaat aaaggtctaa cgtatttgcc acagggctgg cacaaccttg ccatgcctgt
    26041 ggcacgacag taccatacgg atggcactgc catgtcatcg gttaatggca ctaattatgc
    26101 accagtgtcc cgatattctc tccgctcatc actttcttca agttgccgtt ggtatccata
    26161 tcgaatacga tgatcgggag gttgttctct ttacacatcg tggtagcggt caagtccatt
    26221 accttcaggc cccgggtata gatctcatca tacgtaatat cggagaactt ggtagccgta
    26281 ggatctttct ccggatcagc ggtgtaaata ccgtccacac gggtaccttt cagcatgaca
    26341 tccgcctcga tctcgatgcc tctcaaagaa gatccggtat ccgtagtaaa gaacggatta
    26401 cccgtaccgc cggacatgat taccacgttg ccttgttcca gcaactcgat cgcacgccat
    26461 ttattataga actcgccgat cggttccata cggatagccg tcagtacctt cgccttcacg
    26521 ccttgagcga ccaaagcgga gctaagcgcc aagctattga tcaccgttgc cagcatcccc
    26581 atctggtctc cttttacccg gtcgaaacct ttggaagcgc cgctcaaccc gcggaaaata
    26641 ttacctccac cgatcacgat accgatctgt acacccatct cggcgatctc cttgatctgt
    26701 gccgcatatt cattcaagcg aacctcatcg atcccatatt gtttaccacc catcagcgac
    26761 tccccgctta attttaataa gatacgtttg tattgagcca tgttttgtat atatttaata
    26821 tgtaattccg caaaagtaac gaataatccg atattcgcat aaaaaagatc gccccaaccg
    26881 gtgtcggggc gatctaaaca ctaatcccgt gttttgtaag ctgcgaggat tagctaaaat
    26941 tatatgaaac gttactggtt actttttatc taagatctcc aaggtatcgg cagcgatcat
    27001 gaattcctca tccgtaggaa cgacgatgat agtcacctta ctgtccggag tgctgattac
    27061 catctcctcg ccacgcatgc cctcgttctt ctctacatcg atcttcatgc ccatgtattc
    27121 catgttctca caaaccgcac gacgagtcgc ccattggttc tcgccaacac caccggtcca
    27181 aaccaagata tcgcaaccac ccatagcggc ggcataagcg cctatatatt tcttgatgcg
    27241 gtagttatat acgttcaagg tcatgatcgc acgcggattt ccggcagcta cggcagcctc
    27301 gatctcacgc atatcggaag agattccgga aagaccggca acaccacttc tcttattgat
    27361 caagtcggaa aggccggcac catccatgcc ttccttatcc atgatgaaag acaaagcacc
    27421 cgcatccacg tcgccgcaac gagtacccat caacagaccc tcaaccggag tcaagcccat
    27481 ggaagtatcc acgctcttac cattcttgat agcggtgata gaaccaccgt tacctacgtg
    27541 agccgtgata atcttctgat cctcataagg aacacctaag atctcgcaag cacgacggga
    27601 tacatatcga tgactggttc cgtggaagcc ataacgacgt acgccatatt tcttgtacat
    27661 ctcgtaaggc aaaccataca tatacgcata atccggcatg gtctgatgga aagccgtatc
    27721 aaacaccgct acttgaggaa tacccgggat caaagcctcc atcgcccgaa cacccttcaa
    27781 gttagccggg ttatgaagcg gagccaaatc agagcactcg attaccttat tgattacatc
    27841 ctgattgatc aatacactgg aagcgaactc ctcgccacca tgtaccacgc gatggcccac
    27901 ggcatcaatc tccttatagt ccttgatgca gccataagta gcgtcggtca acacgctcag
    27961 gataaactcg atgccttctt gatggccggg gatctctctc tcgataacca ccttcttgcc
    28021 atccttgtcc gtcaatttca agaacgcgcc cggcaaaccg attttctcga taccgccttg
    28081 agccataacc tcaccggagg tcatatcgaa taacttatat ttgatagaac tactaccgca
    28141 gttcaatact agaatcttca tattattaag tcgttaggat tattatatta ttttgcggat
    28201 ttcaaaccga tggattgatt acaagcgatc gctaccatct tataaatatc gtctacggag
    28261 caaccgcgag acaagtcgtt caccggagca gccatacctt gaaggatcgg accgacagcc
    28321 tcagcgccac ccaaacgttg aaccagctta taagcgatat tacccacctc caaagtcggg
    28381 aataccaaaa cattcgcttt accggcgatc tcgctacccg gagctttctt gctacctaca
    28441 gcctcaacca aagccgcatc ggcctgcaac tctccgtcga tcttcaaatc cggagccatc
    28501 tccttagcca aacgagtagc ctccactacc ttatctacca tctcgtgaga agcgctaccc
    28561 ttcgtagaga agctcaacat agccacacga ggctcaacgc ctacgatatt acgagccgta
    28621 gcggcggtag cgacagcgat gctagccaac tcttccgcat tcggattcgg cataaccgca
    28681 caatcggcaa ataccaaaat accatcatcc ccatattgag gagtcttcgt gaacataagg
    28741 aacgcaccgg aaacacactt catgcccgga gccgtcttga taatttgcaa agcaggacgc
    28801 aatacattac ccgtcgtatt ctcagcgccg gcgatctcgc cgtcagcgtc acccgccttg
    28861 atcatcaaac aagccaagaa caaaggatct tcaactagaa ccgcagcctt ctcgggagtc
    28921 atacccttct tttggcgaag ttggaaaagc aagtctgcgt acgcggcttt cttctcgtga
    28981 tttttcggat cgacaagagt tgcctcaccg atgtggttca gtccgaaacc agccgccaac
    29041 tccttgatct cagcggggtt tccaattaag ataatgtctg ctacaccgtc ggccagtaat
    29101 cggtcggcag ctttaagggt tctttcctcg gtaccttcgg gaagaacaat acgctgcttg
    29161 tcagctttag cgcgcgcaat aatgtcttgc attaaatcca tagcggaaga tattttatat
    29221 tatttaataa ttgtactcgt aatccggcta caaaattagg cataatgcaa tatagagttt
    29281 acaaaatagg caaaagaatt acaggtagag ataccagttt cagatctttt aacagtaatt
    29341 cgtcacttcc cgctccccgg agagtatttg ttgcagttct tccgctgtca cattcacact
    29401 taacttacct ttatgggcca cggagatctt tcctctctcc tccgagacaa taataaccag
    29461 cgcatctgtc tccaatgaca tccccaaccc ggaacgatgg cgcaatccca tatccttggg
    29521 aagggtggcg ttctgggcga ccggcaagat acaaccggcc gccttgatcc ggttatcggc
    29581 tatgatcatg gcaccatcat gcaacgggct gttcttaaag aatatattct cgatcaagcg
    29641 ggcatttaca tcggcgttga acatctcgcc cgtatgctca tagatagtca agtccatatc
    29701 ttgctggatc acgatcaagg cacccgtctt tttccgggcc atattcatac aggccaagac
    29761 aacaggagcg acaaacttcc cttctttctc cgggtcgtct cctcgtttgg aaaaaagttt
    29821 tcctaggaat ttccagcccc ggtgcgaacc taacgccaac aggaaacggc ggatctcgtc
    29881 ttggaagagg attaccaaaa ccacgaaacc tacgctaata aacttatcca agatggcccc
    29941 catcaaccgc atctccaata cctgcgagat caagatccat acgacgatga atgatacgac
    30001 tccactgaat atagccaatg tgcccgagct tttcatcaac ttataggtct ggtacaggaa
    30061 gaaagccacc agcaatacgt caatcaagtc ttttataccg aaatgcatcc acatagttaa
    30121 ttgagaattg aaagttgaaa attgaaaatt atttgttggt catttgacct atgacgcgaa
    30181 tggcttccac tgcttccctc acatcatgta cacgaaggat attagcgccg ttcaagagag
    30241 cgtacgtatt caatacagtc gttccgttca ggctatccgc aggggttcca cccagtaatt
    30301 tataaatcat gcttttacgg gagactccaa ctaataaagg caactcaaaa atagagaact
    30361 cctttaaatg gctcatcaat tggtaattct gctccaacgt cttactaaag ccaaagccgg
    30421 gatcgaggat gatatcattc acccctaaaa gccgaagctg gcgtaccttc cgggaaaagt
    30481 acagcatgat ctcctccatc atatccgggt aatcagtatg cctctgcata gtttgagggg
    30541 ttccacgcat atgcatcatg atataaggca ccttcaaatc cgctaccgtt tggaacatat
    30601 ccgcatccaa ctcaccgccg gagatatcgt taatgacagc cactccatat tcctctacgc
    30661 aacgacgggc aatccccgca cgaaacgtat ctacggacac cgggatatcc gggtaatgct
    30721 tatttaatat atgtaaggca aactccaaac ggcgcatctc ttcctccggg gtaacctcag
    30781 cggcatccgg acgggatgaa taaccaccga tatcgatcca atcccctccc tccgataaga
    30841 tttcccggat acggtcctcg atagcggtct cggtctgttt gcggctgccc gcataaaaag
    30901 aatcaggggt aatattcaag attcccatca ccaacggtgt cgctaaagaa gtaagtgtcc
    30961 ctctaatatt gagcgtttta tctaacatga tctttcctta tttccagcaa agatacaggt
    31021 ttctctctta aaatctcctt ctagattctt cattctttat ttaattgcta catttgcgcc
    31081 gaattagaca ggaataaata tttaacgcaa tacagtcatg agtattatcg acctctatga
    31141 tttatttata cataaccctc aaataacgac agatagccgg aactgtccga agggttctat
    31201 cttcttcgcc ttaaaaggtg ataaattcga cggaaatcaa tatgccggga aagccttggc
    31261 atccggctgt gtttatgccg tcatagacaa tcccgattat tatataggtg aacgtacgat
    31321 ccttgttgat aacgtgctga agaccctgca acaattagcg caccatcacc gcaaggtact
    31381 ggggttgccg atcatcggaa ttaccggaac gaatggcaag accacgacca aagagttatt
    31441 ggccgccgtg ctctcaacga aattcaattt actatatacc gaagggaatt tcaataacca
    31501 tattggcgtt cccttgaccc tgctccgatt gactcatgac catgagatgg cggttatcga
    31561 gatgggcgcc agccatccgg gagacatcaa ggaattagtg gatatcgtcc atcctaacta
    31621 tggcatcatc acgaacgtag gccgtgccca tctggaaggc ttcggttctt tcgagggtgt
    31681 gatccggaca aaaggggagt tatatgatta tatccgtcgc tccaaaggca agatatttat
    31741 caagaaagag aacgagtacc ttcagtctat cgccaaaggc atcgaacaaa tcacatatgg
    31801 aaacggggat gatgcttttg cgtccggaca ggtagtcagt tgcgatcctt tcttagtgtt
    31861 caattggaag caacaaggaa agttgcatac cgtcgaaaca catatgatcg gtagttataa
    31921 cctagataat gtattggccg ccgtcgccgt aggccgcttc ttcaagatcc cggcagagcg
    31981 tatcagccgt gctatcgccg cttacgagcc taccaataac cgttctcagt tcaagaaaac
    32041 cgataataac gaattgatta tcgatgctta caacgcaaat ccgagtagca tgaaagtagc
    32101 tctggacaat ttcatcacca tgcccgtaca gcctaaagct atcatccttg gagatatgcg
    32161 cgagcttgga ccaactagcg acgaattaca cgcggaggtt gtcgaacaga tcaagaaagg
    32221 ccagttcgac aaggtgttcc tctgcggcga gcatttctcc aaggtaggca aagagttctc
    32281 ccccttcgct accacggagg caatggtgga agagcttcgg aaacagccgt taaagggcta
    32341 tcatatcttg atcaaaggct ctcatagcat ggggctggag aaactagcgg atatcctata
    32401 agctatcatc gaacaagacg gttttcaact tctggtacaa gaaggagaga atcaataaga
    32461 taactcccaa gattataaag acgaccacct tcccgatcgt aggcaagagc cacagatcca
    32521 ccatcaccaa ctttagcaat acgatcgaga aggtggccaa actaatcatc cggacaactt
    32581 tcagatgcaa tcgcattccc accgccattt gcataaaacc ggcaagactc aacgagatag
    32641 agaaacctgc gcttaattca tccggcaagc ccaactgatt caacaaatta ttcgttccca
    32701 cggctagtaa tatcgtagac agcaaacaaa tatataaggt catcccatgc gtacgctttt
    32761 ctcttgcgtc aaatgactta taatagtacc gccccaagac aaaaatatgc cccccgatta
    32821 aaagcaagga aacccatagc aggaaccggg gaataaagag atcatcatac ccgacccaca
    32881 aagacattcc tccgaacagg gataaagata gccccaagag tagtccgtat ccccccgcat
    32941 ttcttgacac aggcaaatag cttttcccta ataaaacatt cgcagcaaat aaaaccgcca
    33001 ccgtaaatgt ctcgatatag ctaaaggaca cgatcgaagg atctacatat gaatagaaat
    33061 cgaaaacaaa ggctatatat aatacgacac atcccgtcaa gagaggccct ttcgtcgaga
    33121 tccttgtcgg acgtaccaac caagcgtcta cccaatacga taaccccgta aaaataccgg
    33181 tagcgaacaa gccatttata aatagggaag aatctccgta ccgagccttc atacatccgt
    33241 ggaagacatc cattccgtaa gagcccagcg tcaagaccgg aagtacccaa acgaatatct
    33301 cgtaaacccg cagacggaaa cgactataga accagagaat aatcattacc tctgaagccc
    33361 aaaacaaggt aataaaggtc ccttccagtt ggatcgggat cgtcaccgat acgaacgtaa
    33421 gagcgatacc caataacgta tgcatcaaga aagtgaaagg ttcccctttc cgtttgatcc
    33481 aaaagaaaag agcgaagtta atagccgcaa caaaaagggt taccagacct ttgtaattct
    33541 gctcaagctc catattctgc aggagacaaa gggcaaagaa caggaatacg aaattgttca
    33601 atccgatcac tcctaataaa tattgattga tcccccggat attgattcgc acgatggaag
    33661 cgaccgataa taagaagatc aaatagaagg cgatagagaa aataagtaaa tgcgttaatt
    33721 ggacacttcc catcaaatcc agatccgcag catacgtata acccgcaaag acgatccaag
    33781 tcaaggcaaa acaaattaca ggcaattccc cccacttctt atagatagat agcccgaaca
    33841 tccctaggtc caagatcatg acataagtaa acagcaccca ataacttcca tccccgctgc
    33901 ccactaagaa tggagcgata aatccaccca ccaaagcgat aatcgccagt tccctacgat
    33961 tatagagtat agataaagac gacataaacc cggtaaacaa tacaagcaag ataaaagcga
    34021 ccgtttggct gaacagcccg taataatgat aggcgatcgc caccgttaca taaaagatcg
    34081 caaaagcgcc tcccgccagc aaagagctaa aggtacgata ggaatccttc aaacgccaag
    34141 ccacgaatag aagtaatccg cccatcccaa agccaaggat cgtacgcaag gtctcgttta
    34201 tccattcctt atctatcgca tacttcacga aaagacccat acccaagacg agtatcagga
    34261 taccgatttt accgaataaa ttctcaccga tatatttctc ataattgaca ggcttccgca
    34321 ccttctgggg ttgaagattt ctcgcaggtt cgacaatcgc ctttacaggt tcaggttgta
    34381 cgaaaacttc cggctctttc aaggtctcag gctccggttc ctttatctcg tccgcaactt
    34441 ccgaactatt ctccaaacgt ctacgcaagg cagcgatctc tttcgataat tcctccgtct
    34501 tctcctgtga tttggatatc ttattacgca agtttatcca aatcatgatc agtaatagaa
    34561 gtatcagtaa ggtatattcc ataaactcta aaattataag cttgccgcaa tatacgcatt
    34621 tatttatata aaagctttcc gaaccataaa aaagtcccga cgatacgaat atcgccggga
    34681 gcaatttttt atccggtttc cttcctcacg gaaatactat cggaagaact tttttacttt
    34741 agtattaacc acacgttccc ccatcacggg atactttgct gtgtggaaat tatttaatta
    34801 aatatattta gatagagacg ggacgtgccc gcctctactg tatcatttcg aataaaataa
    34861 ttatttaaca accaccttaa cagcagcctc accctctaca gctacagcta cgataccggc
    34921 aggtacagcg attgtagcgt tatcagatga aagaactgtc tcagcaacca ccttacctaa
    34981 gatgttagag ataacaacag acttgccagc ggcaccttgg attgttacag taccatcgtt
    35041 agcgataaca gagatagcag actcagcagc gatcttgtca ttagatgtag gagtgctagt
    35101 tgtcattacc ttgaatactt ctgcttgctc aggatcagtt gtccaataaa caacattgtt
    35161 caaatgagcc aaataagcat tacgaggtaa atatttctct acatcatact cttcaccttg
    35221 ctcttcagct gcttcctcat cataagccgg attcaaatat tcttgaacag aaaggatctt
    35281 gtaagcctca tcgctatact cagctgcgac ctcaaatgcg acagcagccg gattcaagtt
    35341 catcgcattg attgtatcac ccttgattgc gatagaatct ataccgcata cagaaccagc
    35401 gataaatgca gcacgaacag cctcagcgcc agcagcttca taagcataac ccttaacctc
    35461 tgcagaatcc aatgtattca tcaaatagtt tctagttttc acaccttctt ccgcaaatgc
    35521 attagtagaa agataataca aaggcatagt ctcttcgaaa gtcaagcaag cagtatccaa
    35581 ccacaaagtc aaagaatcat gcgtatatac atcgctcttc aagatagact gtccttctgc
    35641 cttcaataca gcgaaaccat ctttctggct agcgatcatc ttgttatcat cctctgtata
    35701 agaagtgatc tgtacgtgac cgatattcaa agtagcatat gtaggagcat ccttctttgc
    35761 gaactcgaat gtagtattct cagtgttgca ccagctagct gtatatagca ttccagatcc
    35821 agctaaagca gagattgcag aaccataata accatattct tcagtatatt cagaagaaga
    35881 aaccaactta tattcattct ctacaccagt agataagaaa gataatgtaa caggataaac
    35941 accattctct acatcaggct cacccattaa ataataatca gttccatttt catttttaga
    36001 gcataaagta gccttaccta aacgatctgt tacattatac ttgtaaactt tcactccatt
    36061 tgactcagct acagttgaat ttgcctcatc taattcaacc tcttctacct taaatctata
    36121 agcagaagcc aactcaccgg cagctacata caatttgcca tctttaacag ttacatacaa
    36181 gttctccaat aaatcagatt tcaaacggaa tgacaatgca ccattaacca aatcttcttt
    36241 agaaactttc ttataagcta actcttgagc atcctccact ttcgggcctt ttaccaattg
    36301 aactgtatct gttccaaaag aataaatagc cttcgcatca tctattacgc ggataatagc
    36361 accacctcta gtactattag tattccacat attagccaaa ttattagtct cagtcaaata
    36421 ccataaagca gtaggaactt ctgttacagc accagcatga actgtaccgt tctcacagaa
    36481 agagaataca tagtattttc ctttgttctt atttgcggaa tgatcctcat cagacttcgc
    36541 attgttcata tccttaacaa agtaagtata ctctggatcc aatgtagtcg gaagcttaac
    36601 ctcagcgaaa gtacatttag cagcatcctt agtccagatt gtcaatttct ctgtacctgc
    36661 gaagttacca aaagcgatca tctcaccatt agcggcaacc tccatgtcat aacacatttt
    36721 tgacttcttc tccgtatcat ttgcgccttt atatacagga gtagcatacg gataaaggat
    36781 catcttgcta ttatcggaag gatctaaaac caccttgaaa gcatacaact ctttcgcacg
    36841 accattctct aggatcgtac cagctgttac accggtagcc ttatcagcag cagcagcctc
    36901 atctttaggt tgtgcgtcta cagtaagttt ccagaatttc tcagaagaca aattagaaga
    36961 ccaagaagta gagtccacaa ctaaatactt accggtagtt ctatcctgca aagtaacata
    37021 accatctaaa ccgtcaatgt ctgtagcgaa caactctttg cctgccaaag gatttccatc
    37081 cagatttttg tcgaaagtca aagcgaaagg agaaccatac ttattattta acaagtcagc
    37141 agtcatgttt atctttgctg gagctgctac tgtaaagtta atcgcagatg cagatacagc
    37201 cgttcccttt tccaaagtaa caatatctgt tctttcagct tccacatcat ctttagcgat
    37261 gatagaaaca actgtcttat tatccaactg agcagataaa gtaacggcag tcacattctc
    37321 cggagcgata aacgcaccct catttttgaa gttccactca gcttgcttat ccaatgtcaa
    37381 cactctgcct gtagcgctat tcgtcaatgt gtacgcccaa gtattcgcca aagagacaaa
    37441 acgataagtt actttccata aggatttttg ataatcagtg ttcttgatat ccgcagtagg
    37501 agcatcagcc aagatcaaac tatcagtctt tgtataagac tctgtgacag acaaatattt
    37561 accatcctca ttggtcaatt ggtaaacttt gccattttca accttcgcat tagcggtaaa
    37621 ggcagtacat aaagccaagc ccgctacaag agtagaaaac tttttgttca taattctaaa
    37681 attaatatta atactagtgt taattaaaag ctctttatat atgcatccca cctaaatggg
    37741 tacaaaacga ctagtctaaa cgatcgttta aactagtcgt tttataaacc tatcttcata
    37801 cgatcaatag catatactat attttcaata gaatttaccc ttttatcata tattatatat
    37861 gtacgagcgt acatatataa tataattatc aagcaatcaa caaatattcc ttattccttc
    37921 aagtcttata ataatgaaac ttttgttcac ctatgaagta actttagttc cataagctta
    37981 aaactatagc ttgatgccga tgcaactaaa gtcacaaggg caaaacgcct ctttcatgct
    38041 tttattggtc aaaaaagaga gtaatctatg tatttgaaag cttttttcat aaatttgtcg
    38101 ctttataata aactgagtaa aaaatgaata cacacgaact ttgctgcgta ggacacatca
    38161 ccttggataa ggtagtaaca cctaagaaca ccgtccatat gccgggagga acctcctttt
    38221 atttctcgca tgcgataaaa catttcgatg atatcgacta tactctagtg acagccttgg
    38281 ctgaatctga gatgaaaacg gtggaggaac tacgagctga aggtatcgac gttgccgtga
    38341 tgccaagtaa gcacaccgtt tatttcgaga atatttatgg agagaaccaa gataaccgta
    38401 cgcaacgtgt attggcgaaa gcagatcctt tcaccgtgga atatctggag aacatcaact
    38461 ctaaaatctt ccaccttggt agtttgcttg ccgatgattt ctctttggaa gtggtaaagt
    38521 atttagcggg gaaaggctta gtatcgattg actcgcaagg gtatctacgg gaagtaagag
    38581 acaaggatgt atttgccgtg gattggccag agaaaaaaga agtacttaaa tacgtgcact
    38641 tcctcaaggc taacgaacat gagatggagg tgttaaccgg atataccgat gccgtgaacg
    38701 caggaaaagt tatctacgat tggggcgtga aagaggtatt gctgactttc ggaagcatgg
    38761 gatctatcat ttacgacggt tccactttcc ataaaatccc cgcttacata ccgaaagaag
    38821 tagtaaacgc taccggagcg ggtgatactt atatgacagg atatctctat aaacgtgcca
    38881 aaggcgcaag catagaagaa gccggacgtt tcgcagcagc tatgacaaca ttgaaaatcg
    38941 aaggaatagg cccattcaac ggcactaagg aagatgtgtt gcgatgttta gagacagcgg
    39001 aacaacgaat gcctgagtag ttgaaaattg agaattgaaa attattcgct ctctcctaat
    39061 tttcaattct caagtctcta tctttaatta ttcttgaatg ctttgcagaa tgtagtcatt
    39121 agcaagatac aaagccctaa caagccgacc acgatataag cgtatttcat attgaaagcc
    39181 tgcgagatcg ctccgatcaa caaaggtgcg atcaacgagc cgataaagct gatactggaa
    39241 aggatcgtca aggcaattcc caccggagtt ctcgatttag cgcccactaa gctataaata
    39301 gtaggcacca tacacgagat gcccaagcct accaacataa agcctaagga attcacgatc
    39361 acctttaccg tcatcgattc gaacattcca cccaacatgg ctgagataaa aaaacctgct
    39421 aaaataaaga aacccgctaa ttgcaacacc ttctgctttc ctaaaacact ataggcggag
    39481 ttcgtaagaa aacggcctac cgtcatcatc accatgaaca ccaagaaacc aatctgtaag
    39541 gacttaggaa cctgcaatac cgattcgaag taaagtccac tccaatcaaa catcgcgctt
    39601 tccaccacca aggcaaacag cccgacgata cctaactgga tcaacagcat ttccggctta
    39661 cggataaagc tcaacaatgc tggagcttct ttcttctccg cttccttctc ttcctccggt
    39721 gactcaaccg ccacgtcttc ctgcaaatac ttccggctta ccaaaacagt cactccaatc
    39781 aataatgcaa tcaacgtaaa atgccagaac ggagtaacac cggatacgat catgataaac
    39841 ccgatcaaag cccctaaaca agccgccaga ctccaacctc catgaaatga ggccataatc
    39901 gtacgcccat agagtcgctc gataccaatt ccttgcgtat tcaaggatat atcgcaaaga
    39961 ttccagaaca ccccaaaaca gaacaaataa acacccagca gataaatatt atgtgccgta
    40021 cctatcgcga ataaggccaa ggcatacccc aacacactga cctgcgccat aatacgactc
    40081 cccaacttcg acaccaaata acccgctaac ggtatcgcca caaacttacc taccgggatc
    40141 aggaacaaga ccaagcccca atagaaagcg taattcacct caaaaatatc cttcacgtcc
    40201 ggaatacggc tagcccaact agagaaacaa agaccttgcg ctaaaaaaaa agaaagcatc
    40261 gcataacgaa tccgttcctt gggaaaagcg ttgcccaatg tagcattcat tttttcattc
    40321 attatcattt acttttattg ttatcattta ttcgagaaag gggcacgccc cccatttctt
    40381 cgcaaagcta tcaaatatat cctaatatcc taatccccta agtcttaaat gtagaattta
    40441 agagatggct tccctaatga aaaatatatt ttacactttg gctgaaacac ttaattataa
    40501 cttaaacctt cgctcaattg aacaatttga cgatattctc cagcaaccca tacgttgtcg
    40561 ttttccttga atacggtttg ggatggagga ttcatcattg actttccgtc tcgttcaata
    40621 cccaagatca gacaagcgtt cttatcccga atgtcagact gttgaataga tcgcccgatc
    40681 aacggagagt ctggttcaat attaaattgc tctattttga tattattatt aaagctttgc
    40741 gccaactgat ctctatattc tttgtcctgt ttttgtatta tctcctggaa aagatccaat
    40801 tcctcatccg taccaacaat tataatctta tcaaaaggat aaaggcgttc ctctcctcta
    40861 ggtatattga tttgtcgttc acctcgaatg atggaaacga tatttattcc atatttttga
    40921 cggaagttga tctctttcaa actccggccg acaatggagg attcttggcc aacaacgaaa
    40981 tccatcaagt gcaaatcatt gaaaggcaaa gatttaaaga tattatcagt caaaggactt
    41041 ccaatgtttg agtccgttgt tttcccgttg aagttgtcaa taaatctttt ctcgatcgag
    41101 agagaacgct ttttcagttt tttggataaa ataatcatta gcaatatcaa cagggtgata
    41161 ataaatccaa caccagatgc tacattaaat atatggacta tgactggcat tagaatactt
    41221 gcgcaaagga gcagctttat cgctatcaaa gaaaccaatg gtccccggtt gaatttacta
    41281 tcattccata atttcaggaa ttcaggagaa tgattcttct tcataatgat agcccaaaga
    41341 aaaggtaata taatggccaa aataatagat aagctcaata gagccccttt gaagcctaat
    41401 atgttctcgc gaataattgg atttacataa gtgaaaaata tgataatact gaatattgtc
    41461 aatactgtat atagtattac atctagtaac atagatttca acagcttatt ccatgtactt
    41521 ttatgtttga ccgtgttgga tccggaagaa taacggttca acattagttt tatagatgaa
    41581 ggcaaataat tgtcaatcaa ttgatagacc ggggtcgcca tgcgaatcat ataaggagta
    41641 agaaatgttg taacgactga tacagcgaca ataacaggat acagataatc gtctgttacc
    41701 tttaagctaa ctcccaatga agcgataata aacgcaaatt cacctatttg ggtcagagag
    41761 aatcctgatt gtagagctat ctttaatggc tgtccggaca agaggacacc aagactccca
    41821 aaaaagattt gcccaatgat aaccaatatg gttaagatgc agattgggac aaggtattca
    41881 atcaataaat ccggttgtat catcatgcct acagaaacaa aaaatatggc cgcaaacagg
    41941 tcttttaccg gttttaccaa tttttctatc ttctcggcct caatggtttc agccaataac
    42001 gatcccataa caaaagctcc taacgcagag gagaatcccg ctttagccgc aatcataacc
    42061 atacctaaac agaagcctaa tgctatgatt aataaggttt cgtcgttaag aaatggctta
    42121 atctttttaa gaaaacttgg aatcagatag attccgagta atgaccaaaa tataagaaac
    42181 gctcctaact ttagaatact ttccagcatt tccattcctt cgacttgctt gctgactgct
    42241 aaggttgaaa gcaagaccat caaaactacg gccactaaat cttcgaccac caagacgcct
    42301 aatactactc ctgtaaattt ttgccctctg agtcccatgt catcgaacgc cttgaatacg
    42361 atagcggtgg atgacataga aagcataccg cctaaaaata tactgcttag atgcgagaag
    42421 ccaagcgcgt ttcctgcagt atagcctaga aacatcattc cggagactat ggttatagag
    42481 gcgataacag ctgtacctcc tacggtcatc aacttcttga aagagaattc taatcccata
    42541 gcaaacaaaa gaaagatgac gcctatatct gcccatattt ttatattggt aggatcggat
    42601 accgttggta tataaggtac ggcgggcccg gcaagaatgc cagcgacaat ataccccaaa
    42661 acgacaggtt gtttcaagca tttaaaaatc aatgtaatta ttcccgccgc aatcaatata
    42721 accgccaagt cggaaataag aggtgcaatt tcagacatgt tattcattat tttgtgctcg
    42781 caaatttaca tattaactta gaaccatgtt gggataaaac aaaagtactc ttgtcctaaa
    42841 aacatatatg ggaaatattc caggacaacc gcagcaaatt cctcctcccc ccaagagctt
    42901 tatcttaaca gcatgaatac accaatatct ataagcggca gtttacgaga tataaaaaaa
    42961 gggtcttcat tgctgaatac cctttcttgg tgatccgcct ggggctcgaa cccaggaccc
    43021 caacattaaa agtgttgtgc tctaccagct gagctagcga atcatcctat gcgttacttc
    43081 tgtaatgcgg gtgcaaaggt agggatattt ttttaatacg caatagatat ggctattttt
    43141 ttgcgattaa atctgaattt atttcctctt gtttaggttg atgagcaagg cttctggaat
    43201 ctaactcatt atattcatgc aagataaatc gtttataata agataagcat aaggttgtta
    43261 atgggagggc tattattaag ccgataaagc ctaagatcgt tccccagatg gataatgaga
    43321 gtaagatgat ggcgggattc agtcccatag ccttacccat tatgcggggg gtaagatata
    43381 aatcctgtat acattgtacg atacccaaga ctaaaatagc cataccaaag atcaaccaga
    43441 agttctctcc agtctcggcc gaacgcaata agctcaatag aatcatcggg ataataccga
    43501 tcgcctgcat atagggaatt aagttcagca caccgataaa caggcccagc gtgaccgcca
    43561 acgggaaatt aatgatctta aaaccaatcg cgaggagaac ccctacagaa agagcgatca
    43621 acgattgtcc gcggaaataa cggttcatgc tgtattccac atcctcagcc aaaccttgca
    43681 ggaacggacg gtaacgctcc ggtatcaaat cgatccaacc attcgcgatc ttctcataat
    43741 ccaaaaggat gaaaataaag taaagcaaga tcacgaacac gatcgtgata ctgaaaagga
    43801 ttgagaaagt gttcgataag atagaccata actggggcgc aatctgcttc accgctttca
    43861 acaaattctc cttactcaat aactccatga tctgggcgaa gttcacatta ctttccagat
    43921 attccatcca tgaatgcggg atcaaaggga catgaccttc accgggatca tgtgtgcgga
    43981 tcagttctag cgttttatcc gcctcagccg cgatggaagg aatgaccatg actaccagca
    44041 acgttatcaa tagccctaaa gtcaccaata ccgccataat cgataagatg cggctcttaa
    44101 aacataattt atattggaag aactttacga acggttgcat catataagcc agtaaccaag
    44161 cgatcaggaa aggtaacaaa gcgtttcgta ataaggctat caaataaata attcctgaga
    44221 tgaccagtat accgaacact atgcgtatta cacggtcaaa cgtaaaaggc ttgtcaaaca
    44281 gtggattcat attattttca tatctttgct tgcgacaaag atagaataaa gtagaatata
    44341 taaacatcat gatacgtaaa atatcctttt tcttcctcat ttcttgctta tacctttcag
    44401 tgggggcaca gactccacaa cctatcaagc aattcctgcg caagccttat atggaaggag
    44461 cttcattttc cttgatcgtg aaagaggtta acagtggcga gacggtattc gcttacgata
    44521 caatccggca gctgacccca gcctcggtca tgaaaacggt tacgaccgct accgcattgg
    44581 agatactggg cgaggattat cgctttccta cggcattaga atacgacggc tccatcgaga
    44641 acggcttgtt aaaaggcaat ttatatatca agggaagcgg agatcccagc cttggctcag
    44701 cgcattttgc cccggatcat aagcggtttc tacaggaatg gatctccgcc ttgaaaaagg
    44761 tgggtatcca taaaatacaa ggagccgtaa tcgctgatga aagtatattt gacacggaag
    44821 gcacttccct taaatgggtt ggcgaagata tgggtagtta ttatggtgcc ggaagctatg
    44881 ggctttgcgt attcgacaat ctttataaat tagggttgca aaccggagct cccggaaccc
    44941 gcccgaagtt gaaaggaacc gaaccggaat tatccggcat ccatttccat aattacttaa
    45001 cggcccagca agtatcttcg gatagttctt ttatcgtagg ggcgccattc gccacggatc
    45061 gttatttata tggcattgtc cccgctaacc gggaatggta tccgctcaaa ggggatattc
    45121 ccgacccggc tcttttccta gcggattatc tcactaggca attggaacat gaagggatca
    45181 cggtcggcga atcaccgtct tgtttccgta tcttgcggga agccggtagg tggcaacccg
    45241 ggaaacggac cgagattgtt accacttact cccctacgct tcgggaaatc gtggaagtga
    45301 ccaatcatgt cagccataat ttattcgccg atgccttgat caagacgatc ggcctacgct
    45361 atacgccccg taagggagag gtcatatctt cttttaaccg gggtatccag gtgcttcggg
    45421 actattggca agggaaagga ctcgacctct cgtgcgtctg gatgtacgac ggtagcggtc
    45481 ttgcggttac caacaagtta tcaacagctt ttgtggctga tttattgatt tatatgaaaa
    45541 cctgttcaca acaacacaca gccttctacg aatcattgcc cgcagcgggg gtagaaggct
    45601 cggtgaggaa cttcttaaaa ggctcatccc tccaaggaaa agctcatctt aaaagcggaa
    45661 gcatgagccg ggtaaaagga tatg
//
LOCUS       DBMDTB010000020        45335 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_329_length_45335_cov_11.150219, whole genome shotgun sequence.
ACCESSION   DBMDTB010000020 DBMDTB010000000
VERSION     DBMDTB010000020.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 45335)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 45335)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45335
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_329_length_45335_cov_11.150219"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..1142)
                     /locus_tag="ACZPB4_05260"
     CDS             complement(<1..1142)
                     /locus_tag="ACZPB4_05260"
                     /EC_number="3.1.6.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase family protein"
                     /protein_id="HIR1097663.1"
                     /translation="MNKYILTAACGLAFSAASAQTKALPDSPNILLILVDDLGYGDLS
                     CQGAAKDIQTPHIDKLLNEGVRFTNFHANCPVSSPSRASLLTGRYPDMVGVPGVIRTH
                     KEDSWGYLSEDAVLLPQMLKKRGYHNAMVGKWNLGLESPNTPTERGFDFYRGFLGDMM
                     DDYYTHRRFGNNYMRENLKEIDPQGHATEIFSDWAIRYLSDMKQKQEPFFLYLAYNAP
                     HTPIQPPQEWLEKVKKREPSLPEKRAKIVALIEHLDYNVGRVYEALEQNGQLENTIII
                     FTSDNGGQDDAGANNGPFRGAKQDMYEGGIRVAGGIYWKNQIRPAVRDNFVMLSDMFP
                     TLCDLTAVPVSHEIDGISILPLLRGEEQDTGDRMVHWVRREGNSRYG"
     gene            complement(1167..2546)
                     /locus_tag="ACZPB4_05265"
     CDS             complement(1167..2546)
                     /locus_tag="ACZPB4_05265"
                     /EC_number="3.1.6.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase family protein"
                     /protein_id="HIR1097664.1"
                     /translation="MKTLKSLSVLTAAVLSNSLSLNAASDAVNKPNFVIIFCDDMGYG
                     DLSCYGNPTIRTPNIDRMACEGMKLTQFYVGAGVSTPSRAALMTGRLPVRNGLYGDRV
                     AVLFPNSKAGLGQDEVTIAKVLQQNGYATGCVGKWHLGAFSPYLPTDHGFDTYFGIPY
                     SNDMSPVQNKGAHARNFPPTPLIVDGKQIESEPDQGELTRRYTEKAVSFIKDHSKEPF
                     FLYFAHTFPHIPLYTNARFEGTSKRGLYGDVVEEIDWSVGEVLKALRENGLDENTFVI
                     FTSDNGPWLTKHENGGSAGPLKDGKGTWWEGGFRVPAICWMPGKINPAINDEIMTSMD
                     LYPTFLSMAGIEQPKDLVLDGVNQTGLLFEEKHSARDEVYYWWGSELMAIRKGEWKYY
                     FKTIKDQYLRTCKIETPAEPLLYNVETDISERFNQAEKHPEIVKLLIEAGEKHKKGMK
                     IKPPVCDMM"
     gene            complement(2559..3965)
                     /locus_tag="ACZPB4_05270"
     CDS             complement(2559..3965)
                     /locus_tag="ACZPB4_05270"
                     /EC_number="3.1.6.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase family protein"
                     /protein_id="HIR1097665.1"
                     /translation="MKLISNIISVLAFSGAAVATQAAERPNVIIVFIDDFGYGDLGCY
                     GSTKHRTPHIDQMAKEGIRLTDFYVGSSVSTPSRSALLTGCYPRRVSMHVNADPTPLM
                     SKGRQVLFPASHKGLNPGEITIAELMKEQGYATACIGKWHLGDQLPFLPTRQGFDYYY
                     GIPYSNDMDRPYCPLPLMEQEEVIVAPVGHDSLTIRYTNKTVEFIKSHKESPFFIYLC
                     HNMTHNPLAASPAFKGKSQNGLYGDATEELDWSMGVLLETLKEEGLDQNTLIIFTSDN
                     GADEHFGGTNRPLRGQKGTTYEGGFRVPCIMRWPAKIPAGQETDNLVTSMDFLPTLAH
                     YCGYAVPSDRVIDGHNVSGILEGESMASPTETFYYYQKQQLQAVRWGNWKYHLPLKER
                     IKGPHFPDTEVGEARLYNLANDLSETTNVIDKHPEVVTKMNQWIEQVRSDMGDWGYEG
                     RNQRPAGIIDEPFPRLLK"
     gene            complement(3989..5548)
                     /locus_tag="ACZPB4_05275"
     CDS             complement(3989..5548)
                     /locus_tag="ACZPB4_05275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RagB/SusD family nutrient uptake outer membrane
                     protein"
                     /protein_id="HIR1097666.1"
                     /translation="MKQLLAYCLSIILCVSFTGCMENYLDLYPEDKITSASFPENESD
                     IKLLLNGVYAQLREKEVYNQGLFGFGITDGATPNAFNWGTDEVFNKLGAGRLSSSDGG
                     VVTYRWKRCYEIISRANYLLACMDLVDLSEEAKAKYSGETHFLRGLAYSVLAETYGGV
                     PIILTDISTEEARSLKRASLEETWQQALDDYEVAITNLGVDAPEPGRATKGAALGMKM
                     RAYLYQGKYKEVLSCVEQIDALKKYGLFHSYEGLFDPANENNKEVLFDIQYIEGENSQ
                     GSYIDQYCGTGTGSWTRGSRYVPTDDLVAAYETIDGSPVDPENPYENRDPRLGFTAVL
                     PGSYFLGYRFPNYLYPGGAFNHAGNRLKHLSTRKYRIQDESKLPPSGQSYINDIILRY
                     ADVLLSKAEAIIETNGNVADAIAILNRIRTERDDVKISLLPTSMSREEAREKVRHERR
                     IELALEGRYWSDVKRWKIGKELYPMIIKDHEGSVIETKFPNGYLEYYDLLPIPDSERS
                     LNPNLDQNPGW"
     gene            complement(5553..8930)
                     /locus_tag="ACZPB4_05280"
     CDS             complement(5553..8930)
                     /locus_tag="ACZPB4_05280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HIR1097667.1"
                     /translation="MKEKQESPRRRCLLILIEKIPNAMKLTFLFLVISLLSFTATASA
                     QRVSIVLDNAKVEKVLATITHQTGLSVAYSKQIVDLNRRVSVNFTNAELTNVLDKITE
                     GTSLSYEVKNGKIYLFEKPIANAVTQQAKKITGVVVDSKGEPIIGANVVEKGTTNGTI
                     TDFDGKFILEVSDNATLQFSYIGFMPTTVAIAGQTSLNVRLREDTQALEEVVVVGYGT
                     QKKVNLTGSVSSVKFDEELTNRPITDASQALSGKVSGVWISQNSGKPGDDGAQLRIRG
                     WGTLNNSDPLVIIDGVEGVFSQVNPSDIESITVLKDAASAAIYGSKAANGVVLVTTKM
                     GKNNEKTQVELNSYVGMQQIGRHFDLVTNSAEHMTMANQALVNGGENPLFSETLISNF
                     ANGTDPYKYPNTDWYDSLYRNALITGHNLSIRGGSEKLSSFLSLNYLSQEGILMNSKA
                     ERFGIRANVEYKVNSWLRVGARLNYTRRNSQEPFDLFRVFEQQQGAAPFIAPYTRDGR
                     FGSVEAIKDDGTLLYTTYQPVIDASNGATKTSKDYMAVNAFATVDFTKDLNLQVTWAS
                     NGNWKMVDKYNETLYGYTDSGIETIPKNYNRDGIVLSREQVSTMRNNFQATLNYSKRF
                     ADKHYVAAILGTQLENYSIKNVFARRTNPPKEGLTQVDAGTEGIKGEGNFEGLRMASY
                     FGRLNYAFADKYLFEMNLRADASSRFKRGNRWGVFPGFSAGWRLSEEAFIKNLNLFSN
                     LKLRASWGQLGNQTIEGYWPYLTVISQNYDLSYNYGGSLAPGAAVTALVDEDITWETT
                     SSLDIGVDLGFLGNKLNIEADYFNKKTTDIIVQLPIPNVLGDKTAPFENVGEMKNNGF
                     ELVVNYDNLETSRDRLGFNVGLNFTYIDNKVTKFQGGNSPDQLYLIREGYPYKALYGY
                     KAVGIYQSDEEAAQHMHSNGLKPEMGNLKYEDVNNDGKLDYQDKQILGNTIPKITYGL
                     TAGLRYKGFDLNILFQGLGQANAFTKSGMTRMQYEWLTISDKWRDAWSPENPDSNIPM
                     LRFDSSWDTYDSSFWVHRIDFLKLKNLQLGYAFPEWITSKLKMQRLYVYANAQNLFTI
                     MWKKGYEGYDPERNTFDSGTNYYPTPRIFTFGINLNF"
     gene            complement(9144..10133)
                     /locus_tag="ACZPB4_05285"
     CDS             complement(9144..10133)
                     /locus_tag="ACZPB4_05285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecR family protein"
                     /protein_id="HIR1097668.1"
                     /translation="MKIPDLSIIEKTLNNEATSEESCEVVRWFKTPEGQAWLAERIDQ
                     DEKTIHMGEEEAWIDHPIPSAVMYQNIMRQLRRQKIRRFIAYAAAVFIPIALIIGLFI
                     RINSQVDLLADDGYDEVYVPNGERMQVLFQDGSKVHLNSGSRIRYPKKFGLSERKVYL
                     EGEAWFEVAKNKNRPFIVDLSYMDIKVLGTTFDVKAYPEEEAIFVALETGSIELKSRS
                     FKSYQLRPGEKAVYNKASGRCEVLRSHDVKMYSAWRRNVLVFKSAPLSDVMKTLARTY
                     DISFDVKDSAALRYTYTITTDSVNLTTVLKELEKITPVLFEEKGGKIEVRMKK"
     gene            complement(10169..10762)
                     /locus_tag="ACZPB4_05290"
     CDS             complement(10169..10762)
                     /locus_tag="ACZPB4_05290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HIR1097669.1"
                     /translation="MSFFQKSIRSDEDLLTSLRQGSEDAFTVIYERYHKLLYVLAYKY
                     LKSTYSSEDAVQQVFLKLWEARSLLMVNVNLRNYLYTMLKNHVLNEIRNNNSAVEKNY
                     EIVQSAPEYEDELLIKIEEQDMMSHFYQAIDHLPEQKRQVCLYKLKGNLSNQEIADKM
                     NISVPTVKTHYAQAIKILRAHFERLFLFLLYLWNSSY"
     gene            complement(10772..11416)
                     /locus_tag="ACZPB4_05295"
     CDS             complement(10772..11416)
                     /locus_tag="ACZPB4_05295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HIR1097670.1"
                     /translation="MEKQSFIALVKRYYPWICSMEKAAFRIHDDVNQKYDHVLPYGFH
                     LKMTVSYVSRYGYLVAETEADILILYASAFLHDTIEDARMTYNDVVKFLKEFKGGGFV
                     LPEGVRQHLEDQVPEIVYALTNEKGRNRGERANDLYYQGIRQTKFASFIKICDRLANI
                     QYTMMFVFANRMLDVYRREYPEFIRSISEGAVTQVPDAMKEEAERLLNSESYII"
     gene            11645..12784
                     /locus_tag="ACZPB4_05300"
     CDS             11645..12784
                     /locus_tag="ACZPB4_05300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HIR1097671.1"
                     /translation="METIAMMNPFVVGRYVSDKYFCDREGETSFLIKQIENGRNVALI
                     SPRRLGKTGLIQHLFHQESIEKNYHAFFVDIYATTSLTEFVYLLGKAIYDELKPKKTV
                     WTERFFQIITSLRAGFKLDMVTGEPCFDIGLGDIQAPQTTLDEIFAYLETADKPCIVA
                     IDEFQQIGGYEEKNVEALLRTKIQQCKQTMFIFSGSKRHLMSNMFNSSSKPFYQSAIS
                     IGLEPIPIHIYVEFANRLFEQRGKLIDKSVIEEVYRMFDGYTWFVQMIMNELFALTEE
                     GERCSMDKIEIARKNVILTQESSYKDLLANLAPKQKLVLQAIAKEGRAEGLTSSAFIK
                     KYKLPSASSVQSAVKPLLKNDLITQEDGFYRVYDYFFADWMARIY"
     assembly_gap    12969..13068
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(13074..13835)
                     /locus_tag="ACZPB4_05305"
     CDS             complement(13074..13835)
                     /locus_tag="ACZPB4_05305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HIR1097672.1"
                     /translation="MEPEITVIIIDDDLGSIQKLQNDLLAFSEVRILDTATTAELGKR
                     HILKYQPDLVFLDVELPDMSGFDLLDDIRDDILPNLRVVFYTVYDKYILDALRASAFD
                     YLLKPYLIEELEALIERFHTTEPADVACMERSLRKILNRDSRFAIQTVSGLLLVRCEE
                     IFLFQFLGDQRCWQIVLTSRTTHKLKMGTTAKDLLSINNTFVQISQDCIVNLTYLMFI
                     ENKTLRCEFYPPFQEEERIASHRYFKQLRERLDII"
     gene            14058..15059
                     /locus_tag="ACZPB4_05310"
     CDS             14058..15059
                     /locus_tag="ACZPB4_05310"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HIR1097673.1"
                     /translation="MSRKINLIIFLCFILCEVYAQYVPDVLGDGYLRRTFQMPDDYEG
                     KVVCTLVKKPQLDSVKQAVLYIHGYNDYFFQKQLGDSVNAHGYNFYAMDLRKYGRSIL
                     PNQNPFFCKSLKEYFADIDTALATIQSEGNERILLMAHSTGGLITPYYLNSKKGELPI
                     DGLILNSPFLDWNFGWFMEKVVLPTVAFVGRLFPNLTVQGLGDPNYAYSLLKQYKGEW
                     EFDTNWKMIFGHPKKAGWIKAIQEAQQTVQKGLKLDCPILVMSSNKSFPETETWHEEY
                     MTSDIVLDVQDIQKYGEKLGDKVTRDTIPNGIHDLILSQKPYRNDAYQTIFEWLKKQ"
     gene            15119..16606
                     /locus_tag="ACZPB4_05315"
     CDS             15119..16606
                     /locus_tag="ACZPB4_05315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsule assembly Wzi family protein"
                     /protein_id="HIR1097674.1"
                     /translation="MKSVRSIFIGLTCLGMATASFAQEEETTPEATTYKAEIFGSVAS
                     GDNAPFWMVSNRYGIVPLEANNGYLNAGVFHNQTFGKGFRWGAGLDVVAAVPRHRNFF
                     IQQIYAELGYKCLLLSVGSKERYNSLWDRWLSSGDIVQSANARPIPEVNISIPEFTVV
                     PLTKGWMQVKGDFAVGRSFDKDYLANFTNNKQTYVDNVLWHHKSLFVQIKDTRNDFPL
                     SGVIGVQHWAQWGGTSTNPKIGKQPQSIKDLIRVICGSEGGGDATVSDQINVLGNHYG
                     SYDFKLAFTQPNWQVSAYYQHFFEDKSGMIFVNNTDGLWGGQLDLPKFPWLRKVVVEY
                     LVTRDQSGQFHFIDFDHDLHPGVGGGGDDYYNNGEYTTGASYFNRAIGSPLIPSPEYN
                     ENGSLGFKNNRVRDWHFGAEGAISSQVSYRVLVTVMNSWGRHATPFLSKKRGASGLLD
                     ISYQHPRLSGWEFTGSLAADAGSMFGDNFGFSLKVAKRGILKSWK"
     gene            complement(16616..17353)
                     /locus_tag="ACZPB4_05320"
     CDS             complement(16616..17353)
                     /locus_tag="ACZPB4_05320"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HIR1097675.1"
                     /translation="MGRILYIVYLWLFFVPVFLVLTILTAVTVIIGCLLGGEKIFAYY
                     PGMIWSRLTCYLALCPVTVKGREHIDRKQSYVFVANHQGAFDIFLIYGFLGVPIKWVM
                     KAGIAKIPFVGAACRAAGFIFVDNSTPKAAARSVLEAERCLRNGASVVVFPEGSRTYT
                     GKMIRFKKGAYQMALDQHLPIIPITLNGPFDVLPIGSLNVHRHRMEMVIHPAVSTENI
                     DTSHKGMQAFADQTQEIIASALWEEYK"
     gene            17491..17661
                     /locus_tag="ACZPB4_05325"
     CDS             17491..17661
                     /locus_tag="ACZPB4_05325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097676.1"
                     /translation="MNELIKNLGVIVLIIGAAVLAVPFFTGGMTNSILLTGLGLVLLG
                     YFGHIVINKRVE"
     gene            complement(17766..20525)
                     /locus_tag="ACZPB4_05330"
     CDS             complement(17766..20525)
                     /locus_tag="ACZPB4_05330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase domain-containing protein"
                     /protein_id="HIR1097677.1"
                     /translation="MKQLGVILYLLCLTTCYELWATPHNVAYQAKVSCSSALSQEQEG
                     KYVIDQVIRISGKGEWVAKTKLDARGRVYPYPWIQLDWDHAIYTNKVILYDRVDERSH
                     CAAGTLFFSDGSSVTVNLIPNDGAPRVVEFDTRKTEWIRFQMTDGEGQDLGLSEIEVY
                     PAPESYPDYISWVNPYVETAKGRYFFFVTGSLPFGMISSAPLTRNINQGGGGYNYNST
                     KVLGFPQIHNWMISGLSLMPVKDEVDVCRGDKVWRSSFSHDDEIVQPGYHRLFLDTYK
                     IWVEQTVTDRVGLYRFTYTQDGLAKVLVNLGGHIATSTLLNAHVTKVNDTEISGYFDT
                     AGRVWGGVDVAKVYFVVQFDKPMDALNGWVGDRKETDINSLIGSPELITVPKSSFKQS
                     PSSGVEACFGSFKAGDELLLKTAISYVSEENARENIERECQHWDFDQVKSASERIWNE
                     WLGKIDVQGGSFQQKTKFYTDLWHVLLGRHKIDDSNGEYPDYLSGGERIGKQTRIHTI
                     APKFQVRTLPKDKTGKSRFHMYNSDALWLTQWNLNTLWGLAYPSVLDEFSASFIEYDK
                     NGGLLPRGPSIGSYTYIMTGCPATSLITSAYQRGVFHKWSPKEGYAAMKRNHEKGGML
                     AFDMDKELEFYIKHGYCPEEAGLTIQWAFEDWALGEMAKAMGKLKDYNYYRNRSLGWP
                     ASWHPDLRLMMPRKETGEWVHLDPLSERGFVQANAWQATFGLSHDIETLARLMGGNDS
                     LATQLNYVFEMSKNARFLSSYVSYANQPGCSNAHVFSHVGKPWLTQYWVRQVAKQTYG
                     DITPERGYGENDEDQGQMAGISALMAMGLFSLDGGSAYNPMYDITSPVFNEITIRLDS
                     RYYKGNEFKIKVHDNSPENCYIQKASLNGEMYHKYQLPHTVFEQGGLLELWLGDKPNK
                     EWGTQ"
     gene            complement(20609..22240)
                     /locus_tag="ACZPB4_05335"
     CDS             complement(20609..22240)
                     /locus_tag="ACZPB4_05335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0019867 - outer membrane [Evidence IEA];
                     GO_function: GO:2001070 - starch binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RagB/SusD family nutrient uptake outer membrane
                     protein"
                     /protein_id="HIR1097678.1"
                     /translation="MKKIFYFAASALMMCSCADSFLSEEPVGEFLPGQVESEENIEGI
                     VTGAYAVLDGYYASDAINSGCSNWQFGDVVSDDAYKGGGGTGDQNQIHLMEIFNANPT
                     GIDFEARWAALYEGIKRCNQAIRLLNGSEVKNKEQRLAEMRFLRGHYYFNLKIIYNQI
                     PWIDETLVDPNEYNKKSNIEFSSDQLWEKILEEFSAAYKVLPESQADYGRPTKMAARA
                     YMAKVYLYQSKWKECLEACDEVIQSGKYELFPDFRNVFLPENDNCSEIIFAIQLSIND
                     GSPNNENGSYGDRLLPPGGPYPVYGFLRPTQNLVNAYKTDVKGLPYNDGKDVSENDYV
                     DVRLDHTLARPNIPFMDVQLYDWTPREASVYGPYSPKKRLVSLNSTYYSPIWPYVNAL
                     NFYVIRYADLLLWRAEAAIETGDLETGRKYINMIRERAKNTQHVKTMDQSQDAANYKV
                     GVYDEPFKSKNEAVQALRMERRLEMAHEGIRFFDLVRWGVADEVINAYIAKEKVFRSH
                     LQNAHFVKGKHEYFPIPQSMIDICGTEVMKQNPGY"
     gene            complement(22261..25710)
                     /locus_tag="ACZPB4_05340"
     CDS             complement(22261..25710)
                     /locus_tag="ACZPB4_05340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HIR1097679.1"
                     /translation="MLMSAFHLRKRNLTRYLPQSNRILNLGTAFTFLTAFQLYAGTSY
                     SQTTTLSLSLKNATLEQAIDRIEEETGYSFLYADHVLDVSRVVNLEANNKDINLVLSR
                     VFDNMNVDYKIVDKQIILSHKLESIPLAQQQGHTVQGVVLDSNQEPVIGANVLVKGTT
                     VGTITDIDGRFTLEVPDNAVLVVSYIGYLSTELVPGSKTDLTISLKEDSQNLDEVVVV
                     GYGVSRKKDLTGAVSVLKIDDLKDTPVSSVDQMMQGKLSGVNVMPDNMPGGGVAVRIR
                     GFSTIRNNDPLYIIDGIPVDGGINFLNPNDIESMQVLKDASSASIYGARAANGVVIIN
                     TKRGKEGEFNVNLDAYFGVQKAAKQLRMLNAQQFGDMLWQAMKNDGKTPSHDIYGNGD
                     QAVVPEYLDSDHLIPSDDVDWVDEILRAAVVQSYNLSFTKADKKSNQLFSLGYYDQQG
                     LVKFSDFKRVSGRFNSEYKLFDDHFRIGENISLSHSWGTSVSNNAALGGTLYEAYKFQ
                     SITPVKNLEDEYAGNVFSDIPNPMGKLYRNKDNQDKKSRLVGNLYAELHLFDGLMFKT
                     SFGVDYNNLYRRSFSPKYDELNASEKLSSLSNRNAWNFNWVFTNTLTYNKTFGDHTIN
                     ALLGMESLRNRYEYFTASRDGFPSDDPNFLFLDAGDVGTQKNSGAATEYSMVSYFGKL
                     DYNYHDRYLVAFTLRRDGSSRLGNNKWGNFPAASVGWRISNEPFFDVEAISNLKVRVG
                     WGQNGNSDVPSYATIDSYKSNSTNSNYPIDGNQSGVDLGLVQTRNGNVNLKWETTTQT
                     NVGVDLGFLNGDLNLTLDYFNKDTKDLLWRRALPASIGGTNMTVWDNVGKMNNKGFEM
                     EINYQKQINQDFGFSVAYNFSVIKNKMTELNGVDYIGLSSSELHGRNFDQETSRSAVG
                     QPIGSFFVYEADGLFQSDAEIQNYKNDRGELLQPNAKPGDIRFKDLNGDGVINSDDRD
                     FKGNPLPDCSMGLTLGFNYKNFDVSAFFQGVFGNEVYNLTNYLGEFYNQAQYNKNSTI
                     LDAWRPDNTDTDIPRVTLDDPNNNIRPSTYYIHNASFVRLKNLKVGYTLPDKVASKLK
                     LKRTYIYLQGQNLFTITGYEGIDPEVGLQSYSSENRNLDMGVDRGVYPLPRTFTLGVN
                     VSF"
     gene            complement(25753..26700)
                     /locus_tag="ACZPB4_05345"
     CDS             complement(25753..26700)
                     /locus_tag="ACZPB4_05345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecR family protein"
                     /protein_id="HIR1097680.1"
                     /translation="MRESGDEKSTLRQIEKIKALSEDMLEYQAIDVHKAWQSMERRAK
                     RKASMRMFSLFFTRAAAILVVPLLISSLFFSYLYYTTGRNVKTGASVVFAEISSMPGT
                     ITRLVLPDQSVVWLNAGSRLVYPSVFDEKERKVQLFGEGYFEVEADPEHPFSVSTSEG
                     LRVIAYGTKFNVNAYDDEPFIEAVLEKGKIDVIRNDERIRLEPNKQVVLNKESGVFRV
                     SAVNLDEKMDWRKGRMVFRNTPLEKVLKRLEKRYNVEIVLHKNSNAEYKYRATFTNET
                     LEQILDYLKQTAPIEWSARQLSSHSDSTFVRQRIDVYQR"
     gene            26937..27518
                     /locus_tag="ACZPB4_05350"
     CDS             26937..27518
                     /locus_tag="ACZPB4_05350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma-70 factor"
                     /protein_id="HIR1097681.1"
                     /translation="MERNPTMTDIDFLLRQITTEDNKLSFQRLFELYYPALCIYTKRF
                     ISDRETREDIVQEVFSSIWENRKRIVIRTSARNYLITATKNHSLNYLQRNHEEYVDQF
                     SQEQIPIYAESGEELYTWEELQTLLREALAKLPENYRYVFEKNRFENKSYGEIAEDMQ
                     ISIRTVERYKNKAIEILKTELKDYLPLFIGWLF"
     gene            complement(27570..28598)
                     /locus_tag="ACZPB4_05355"
     CDS             complement(27570..28598)
                     /locus_tag="ACZPB4_05355"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HIR1097682.1"
                     /translation="MLYGHGDDFYNAKNEVKINFSSNVWHGANLDKLKEHLIEHFDKL
                     TRYPEPDAATLKRLLARRYEIKEENIVVTNGSITAFYLLAQAWRGAKSMIAIPSFSEY
                     EDACRLHEHEISFFPTSDDLSELSLEGQDFCWICNPNNPDGKLIHRTELLRLISANPQ
                     TTFIIDQAYVAFTTEDMLKPSDVKTHKNLILVQSISKAYNIPGLRIGYLVASPEIAEK
                     VNKYIIPWSVNAIAIEASKYILIHPAQFTLPIRKWQRETADFIYQLSKLDGLEVIPTS
                     TTFFLVRLKKGTAADLKQFLLDNYGILIRDASNFRGLDETYLRLSTQKSDENQILLEG
                     VKVWLEQQ"
     gene            complement(28645..31644)
                     /locus_tag="ACZPB4_05360"
     CDS             complement(28645..31644)
                     /locus_tag="ACZPB4_05360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 3 N-terminal
                     domain-containing protein"
                     /protein_id="HIR1097683.1"
                     /translation="MRQIGILLLCCISLLSSGAQTVPNLYRAVDQEKMNHWVDSVFDA
                     MSYDERIGQLFMVIANPKSDNRNMQRLMRYVNDIKIGGILFHKGDPVTQAEVTNRLQK
                     ASRIPMLVSLDGEWGLSMRLSGTTRFPKNMMLGAIEDNALIEEYGKEVGRQCREMGIH
                     INFAPDMDVNSNVDNPVIGLRSFGENPEAVAEKGIAYARGLESTGILSVSKHFPGHGD
                     TSEDSHETLPVVRHNRARLDSVELLPFKRYIYDGFAGIMTGHLYVPALDKSHKPASFS
                     KAVVTDLLQKELGFQGLCFTDALAMKGASTKKTDNPSVKALLAGNDILLAPAAPINDF
                     TAVKEAIEEGVLDLEAIEAKCLKILRYKYIAGLNAYKPVETKGLSKRLNSPHAAWMAA
                     KLNSEAITVLKNEDTILPLKQLNKKKIAALSIGDGVGNEFQKMLGEYDSIACFSIGRR
                     STAAQVQQVYNKLQKYDVIICGVHTIRIPESLALRQLAAKKELVYAFFTLPYACKEYK
                     KSIEKAKAVVLAYEGTPLAQEYAAQVIFGGIAAKGKLPVSIPGLYYAGTGVFTEKTRL
                     GYHQPEEVGANPDRLDVIESIVKEGLDEKAYPGCQVLVAKDGMIIYNKSFGYFDYESR
                     QPVTEASVYDLASASKAAGTLLAVMKAYDEKKFTLNNKISDFIPELKESNKKDLSIKE
                     LLYHQSGVTPTINFYLDAIDKDSYKGSLYSSAKNATHPVRFDAKTYVRNDFKYLPDIV
                     SDTRKPGFTTEVARNFYVSDSFKDTVLQDIKKSRLGTRGRYVYSCVNFIMLKMMVENL
                     MKSPMDQLLRDDFYSGLGAWHTTYNPLKRMDTLQIVPTEQDGFVRRQLLRGYVHDEAA
                     AFQGGVSGNAGLFSNANDLAKVLQLMLNQGTYGGERYLSLETSRLFTQSKSPTCRRGL
                     GFDKPVIGNPKASPCGALAPASVYGHTGFTGTCFWVDPDNQLIYIFLSNRVNPSRANN
                     KLGSLDIRTRIQDAIYKAIDRKSQKDS"
     gene            31759..34395
                     /locus_tag="ACZPB4_05365"
     CDS             31759..34395
                     /locus_tag="ACZPB4_05365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor domain-containing
                     protein"
                     /protein_id="HIR1097684.1"
                     /translation="MKLILLIILIIFGFQSSAWGQAPTLSIEAKQEPIQEIMKKIEHQ
                     TGMTFSYDPSILKGISRITFKSDNQSISECLTRLFQKLPLSYQINGTHIILKKRPRSV
                     TISGFVRDKATTEYLIGASVYDSRTQRGTATNNHGFFSLTLPVGVVRLETSYIGYGRF
                     SHTFQPLERDTVMEILLESGEALAEVVVTGSNDTQNPIQAPQMGTIKITRKMIKTIPT
                     LFGEADVIKALQTQPGVSAGTEGLAGMYVRGGNGDENLYMIDGIQLYQVNHLGGLFSA
                     FNAEALKDVDFYKSAFPARYGGRLSSVVDVHTKDGNMKEYHGSAMLGLTSGNLNFEGP
                     IIKDRTSFNASFRRSWLDALSAPGLAIYNKIQKKKGEKFSARYAFTDLNLKVNHHIND
                     RSQAYVNFYFGQDFLKGGSSEFSVGDNITPFENKDFGKMRWGNIALSSGWSYVFNNKM
                     FGTVTLAYSHYQSKLKQETSQYYGTEGDKDYSSRFIETSTRNGINDFGVHANFDYIPT
                     LAHHIRYGTDYLYHRFSPEYIEEKTSENLSPTKRTTGDERLSANELAVFAEDDWAISP
                     IVRANAGLRLNMYNIQKKTYVSLDPRLSVRFLLTRDLSLKASYARMNQYVHQISESYM
                     SLPTDMWMPVSKKLKPLVSDQVSVGAYYNLHKNYSFSVEGYYKWMNHLLDYKDGYNFL
                     PSFVGWEEKLAAGKGWAYGAEFIARKETGRITGWIGYGLMWSDRQFDEINNGKRFPAK
                     YDNRHKLNIVANWKINEKLELTGSWTFMTGNRVTVAFENYEDLGLTPVPPLLPEGGLD
                     YFTERNNVRLPAYHRLDLGINIYRPKKNGHLGIWNISVYNAYCQMNPITIHKRSWINY
                     SHYFETLSLLPIIPSISYTYKF"
     gene            34401..35417
                     /locus_tag="ACZPB4_05370"
     CDS             34401..35417
                     /locus_tag="ACZPB4_05370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4249 domain-containing protein"
                     /protein_id="HIR1097685.1"
                     /translation="MKPIFYLSILLSSMLLTSCYRKFDLEEYRTTPKMVINSAFSPDT
                     VVMASISRTWFHSESKPDVTIRNAKVELYIDGIFKEEMPWKEYSYWKSSRWLGEDRGG
                     WVTDTLYISNTVPQPGQTVKIVASTPEYGTASAEDKIPSKTEIKGLRIIPRKEATGNG
                     GTLVDGDGNISYIEENDVLIYQITFQDTPGKSNYYSLQIWGDDDHLGVLLDFSVDPVF
                     TQQQGILDEVFGSSMVNWRGRVFSDELFDGKEYTLQVKEQLRSDTKYYTKRHIRLYSL
                     SEPYYQYLLSLQNIENEGIMGGLTNVGLAEPVRIYSNVEGGTGIAGGCQWFESLVDIK
                     DLIK"
     gene            35555..35902
                     /gene="rplS"
                     /locus_tag="ACZPB4_05375"
     CDS             35555..35902
                     /gene="rplS"
                     /locus_tag="ACZPB4_05375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HIR1097686.1"
                     /translation="MDLIKIAEEAFATKKELPSFKSGDTITVAYRIKEGNKERIQQYR
                     GVVIRISGHGDKKRFTVRKMSENVGVERIFPIESPFIESITVNKVGKVRRAKLYYLRA
                     LTGKKARIKEKRV"
     gene            36342..36647
                     /locus_tag="ACZPB4_05380"
     CDS             36342..36647
                     /locus_tag="ACZPB4_05380"
                     /inference="COORDINATES: protein motif:HMM:NF024080.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3791 domain-containing protein"
                     /protein_id="HIR1097687.1"
                     /translation="MDKQIELSQTEIELAFASFCIEGTARKLGQPYQEVFARMKRVGM
                     IENYILPNYNILHTESREHVIDNIDVTYFRLFNIPDSLSELYNLRSTDLYLRPKSKW"
     gene            complement(36554..38623)
                     /locus_tag="ACZPB4_05385"
     CDS             complement(36554..38623)
                     /locus_tag="ACZPB4_05385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane beta-barrel protein"
                     /protein_id="HIR1097688.1"
                     /translation="MRRQVLFVGLICVAFLVNAQEEKTIDLDEVTIQASSIIRKKDRQ
                     LIFPSKDQVRRSMDGLDLTRRMSLPRLWVDPNTKSISMANGNVQLRINGVLASSLEVA
                     ALSPEDIKRVEYHDNPGLRYGEGIDIVLDYITIKRTSGGNLGVDLSHQLNTFWMADYI
                     YGKYNRGRSEFSLSSFANGHRYKEAWQDRTEIFHTPDGTFQRTQEGIPGRDYEMYWTT
                     TANYNYTKDDDYFLNAKLNLYYYDYPHNYSDALLRNSESMATTHLIDNNKSLNTRPSL
                     DLYYFRKLPRKQSLAVNVVGTYSNTDSRHTYREELESIPLTDIYTKVDGKRYSVIGEG
                     IYEKELETGRISAGLKHTQAYTDNVYSGSGDYTTHMTESESYMYAQYVGTWKKLVYNV
                     GLGASRNYLSQENVDSYNRWYFRPQVTLTYTINEVLSARYRYTLRNVNPSLSELSNVE
                     QWIDSLQVRRGNPGLSPFLYHNNAVEFHVNTAKVKAGFTFSYQYQPRMVMEETLYDAS
                     RGLFIRTYDNQRSFHRFTPELYLNYSPFGDYLRMNISGGLNHFQSNGNSYSHTYTDPF
                     YVISLNSDVKNFNFNLLIYKRSYSFSGETSREADRFNRLGIGYRIGKVQLSASFSTQF
                     TSSARYRSKNLSAIAPYVTDQRFGDIYPGFEIGFSYHLDFGRKYKSVDRKLYNSDNES
                     GILNSRK"
     gene            complement(38749..40437)
                     /locus_tag="ACZPB4_05390"
     CDS             complement(38749..40437)
                     /locus_tag="ACZPB4_05390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HIR1097689.1"
                     /translation="MPEIRISVAMTKWFVYILLANVCLLLSCGDKSVREKFAEADRLV
                     NENNLDSAVWLLEEQITLSALSDSDKAEYGRRLAWLHLLQDRSLVNDSLIDYSVDYYK
                     EHASEPLLSAYFVKAIYMGDSRKGFEQRRALYREAIDSAYSRSDSTYLVRFYDRLTSL
                     SFGEGLYRETIAESKEWEASPKAGFKEMAYYMAGLSYSRLRMRDSADYYLRLAADSAL
                     AKNIEWYAHHFARNYADFLYDFNPKASIRYLRLLKERYPEREILGSYVMPWINLGELD
                     SARKYIEKNTLDLERSHSDDIASHALNYAYQFILGVKENKPVDISRLGQYCDSLYTVK
                     SQTEKAERERLVDQNRLRRENLRLEMSRQRTFSILVIVSLLSILVAGGVSLYIRNRRN
                     RLIDMEERLEALRQLLNESKQSVAEEEKPDSAFFRKVLLQQLGVIRLMATTPTQQNKE
                     LLQQMTRITNEDVPVDTLLVWDDLYPIIDAVYDNFHTHLVRLSDGRLLEKEIQLCCLL
                     CAGFSTKEISVVTQQSVRTIYQRKTDIRHKLGMDEKEDIIGNISAQTANINFSL"
     gene            40555..41736
                     /locus_tag="ACZPB4_05395"
     CDS             40555..41736
                     /locus_tag="ACZPB4_05395"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1097690.1"
                     /translation="MLQLKRNDLLIGFTISVLLSIFVNFALLMRKYEFETGNPGMGIQ
                     PPDRTMYYLLIWFFVFSFILFIVNSLMYKFGDKLFRRKEYKRVLVVCVTCISIAYGMF
                     HLSPVLYTAIVVEWLGEDGPQPATRDIMIRINRDRMATQTIRPAEHRDIPVPPNPFTV
                     PNSFMTEHLFVFLTVMLSSILIRLLGSKQQMKLEYEQLKTEKLQNSYNALMGQINPHF
                     FFNSLNGLNALIQSGEKQQTLAYLDELSNVFRYILQSNKKELVTLAEELQFVKAYTYL
                     LSVRYEGKLFFSIQADTPYLLWYLPILSVLPLIENAVKHNVISKQYPLQIDIYTTNED
                     KLIISNKIHPKSEDSKGSGIGLKNLWGRYRMLTGKDIQISNRKEYFKVTLPLLNKPIH
                     S"
     gene            41733..42494
                     /locus_tag="ACZPB4_05400"
     CDS             41733..42494
                     /locus_tag="ACZPB4_05400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HIR1097691.1"
                     /translation="MKAVIIEDETTAVNSLKAILAQNTVTQIEVIAELESIEESVDFF
                     RTSPHPDIIFMDIHLADGSAFKIFEQVEIDAPVVFTTAYDEYALQAFQVSSIDYLLKP
                     VTLASLERALNKLRLFDTEERLAHIRQTNRTIQSRHTIKSLLIMLADKFYPLAVEEIL
                     YFYTANEKVTAYTSDGKQHPVDRTLDALGEQLDERLFFRANRQFIISRNAIKDIDLWF
                     GSRLSVNLTLPVPERIIISKTKTPIFKKWILREEE"
     gene            42618..43055
                     /locus_tag="ACZPB4_05405"
     CDS             42618..43055
                     /locus_tag="ACZPB4_05405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HIR1097692.1"
                     /translation="MLKCITFDGDASTLNTLMGYLEKLDKALADVHQVLSKEQTERPI
                     FVREGSKIIRLRREEILFLEGYGDYVKVHRINGKPLLTQVSLKRFEEFLDRNRFCRVH
                     RSYIVSLSHINYIERKRIRIGEELIPISDSYLPALMNNLALQE"
     gene            complement(43145..44350)
                     /locus_tag="ACZPB4_05410"
     CDS             complement(43145..44350)
                     /locus_tag="ACZPB4_05410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097693.1"
                     /translation="MKVTRYLLYPCLLMAASASAQNTMTSSPYSMFGLGEMASGLYGQ
                     NTSMAGVTVGMREGMLMNIENPAGLTALDSCKLFAEASAFVKNERYRSDGSSSSAFTG
                     NFSAFSLGGRIMRRWYMSVGVTPYSFVGYYFKSSQELEGSPGTFVTSTFSGTGGLSKA
                     FLSQGFSLTKHLSVGMNLNFIFGNMTQNEIQSAMTVSREMSGRSFYADFGLQYHRPIA
                     RETFLTVGAIYGYKQRISLKNTVTVTGSSTETPYNQKRVTQYLPQYIGIGSSLAHKKW
                     TYALDYLFRQYGVLNSSDSRVKFRDSHELRLGVCYFPNGFSSSSYWKRMSYKAGVSVS
                     TPYLRLKGQSGGAYRVSVGLGLPVLNGRINTAFYYDRLQLQGNALRRDIMGFTVTYTL
                     SEKFYQVKL"
     gene            complement(44337..>45335)
                     /locus_tag="ACZPB4_05415"
     CDS             complement(44337..>45335)
                     /locus_tag="ACZPB4_05415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4270 family protein"
                     /protein_id="HIR1097694.1"
                     /translation="WHFPYQFDESITGASEKAEKAFKEQYPAVYNHMLYNNSSVSYAP
                     EALAVCSFKPKPKGGEKLEVRLPDALGQDLLSRFHAQDQAVSEERFEDYFKGVAIVPD
                     LAGSESLLTFTVADSSAALVLHYHLSDELSTEKELWFFPNTDTQFNHIDHDRSGTDMA
                     GYPMKGVEIPSAELGNRGVLFGGLGWYTRLEFPYLNNLMQQGTQVEIESALLKIYPEQ
                     GTYSDYNTLPDSLYLYIADENNVVTDAVTDYLGSEVQRGTLSEDNTFNENTYYYFDVT
                     QFMQEELGAFGMYKHNLQLVFNSDDYTGTFKNLTFNDQGGRNPVTLQLIYKVYESY"
BASE COUNT        13171 a        11053 c         8683 g        12328 t
ORIGIN      
        1 ccatatcggg aattaccttc ccttcgcacc caatgcacca ttcgatctcc ggtatcttgt
       61 tcctcacccc gtaaaagagg caagatactg ataccgtcga tctcatgtga tacaggcacg
      121 gctgtcagat cgcataaggt cgggaacata tccgaaagca tgacgaaatt atcacgtacc
      181 gccggacgga tctggttctt ccaataaata cctccggcta cccggatccc tccctcatac
      241 atatcctgct tcgcgcctct gaacgggccg ttattcgcac ccgcatcgtc ctgccctcca
      301 ttatcagagg taaatataat gatcgtattc tccaactggc cattctgttc caaggcctca
      361 tacacacgtc cgacgttata atccaaatgc tcaatcaagg cgacaatctt agcacgcttc
      421 tctggaagtg acggttcacg ctttttcacc ttttccagcc attcctgagg aggttgtatc
      481 ggggtatgtg gggcattata agctagatac aagaagaaag gctcttgctt ttgcttcata
      541 tccgacaggt aacggatcgc ccaatcagag aaaatctctg tagcatgtcc ttgtggatcg
      601 atctctttca agttctcacg catataatta tttccgaaac gacgatgggt ataataatca
      661 tccatcatat cccctaaaaa tccccggtag aaatcgaagc ccctttccgt aggggtattc
      721 ggagactcca atcctagatt ccattttcca accatcgcat tatgatagcc tcttttcttc
      781 aacatctggg gtaataatac ggcatcctcc gacagatacc cccagctatc ctctttatgc
      841 gtacgaataa ctcccggtac gcctaccata tccggataac gaccggttaa taaggaagct
      901 ctactaggag aggagaccgg acagttcgca tggaaattcg tgaaacgaac tccttcattt
      961 aataatttat cgatatgtgg agtttgaatg tccttggcgg ctccttgaca ggacaaatca
     1021 ccatatccca aatcatccac caaaatcagc aggatattcg ggctatccgg caaagccttt
     1081 gtttgtgcgg aagctgcgga aaaagccaat ccgcaagccg ctgtcagtat atatttattc
     1141 atctatctgt tgtttttaat ttcccattac atcatatcac atacgggagg tttgatcttc
     1201 attcctttct tatgtttctc accggcctcg atcagtaatt tcacgatctc cggatgcttc
     1261 tccgcctgat tgaacctctc cgagatatct gtctccacgt tatacaacaa gggttctgcc
     1321 ggagtctcga tcttacaggt tcgcagatat tggtccttga tcgtcttaaa ataatacttc
     1381 cactcccctt tacggatcgc catcaactcg cttccccacc aataataaac ctcatcacgg
     1441 gcggaatgct tttcctcaaa caataatccg gtttgattca cgccatccaa tacaagatct
     1501 ttcggttgct cgatacccgc catcgagagg aaagtcggat ataaatccat cgaggtcata
     1561 atctcatcgt tgatcgccgg attgattttt cccggcatcc aacaaatggc cggaacccgg
     1621 aagccacctt cccaccaagt acccttgcca tccttcaacg gacctgcgga accaccattc
     1681 tcatgcttcg tcagccaagg gccgttatcg ctggtaaaaa taacaaacgt attctcgtcc
     1741 aagccatttt cacgcagagc cttcaacacc tccccaacgc tccagtctat ttcctcaacc
     1801 acatctccgt acaggcctcg tttgctcgtt ccctcgaaac gggcattcgt gtacaatggg
     1861 atatgcggga aggtatgagc gaaataaagg aagaaaggtt cctttgaatg atccttgatg
     1921 aacgataccg ctttctccgt atagcgacgg gttaattctc cctgatccgg ttccgattcg
     1981 atttgcttac catccactat caatggagtc ggaggaaaat tccgtgcatg cgcaccttta
     2041 ttctgaacgg ggctcatatc attggaataa ggtatgccga aataggtatc aaaaccatga
     2101 tccgtcggta aatagggaga aaacgctcct aaatgccatt tgcctacaca gccggtcgca
     2161 tacccgtttt gttgtaaaac tttggctatc gtaacctcgt cttgccctaa cccggccttt
     2221 gagttaggga aaagtacggc cacacgatct ccatacaatc catttcgaac cggcaaacgt
     2281 ccggtcatta acgcggcccg acttggcgta gagaccccag cccccacata aaactgggtc
     2341 agcttcattc cttcacaagc catacggtct atattcggtg tgcggatcgt gggattccca
     2401 tagcaactca aatccccata tcccatatcg tcacagaata tgattacaaa attaggctta
     2461 ttgaccgcat ccgaggcagc gttcaagctc aagctgttcg ataataccgc cgctgttaaa
     2521 acagacaatg atttcagtgt tttcatatgc gtatcttttt atttaagtaa acggggaaaa
     2581 ggttcatcta taataccggc aggacgctgg ttccggcctt catatcccca atctcccata
     2641 tcactacgaa cctgttcgat ccattgattc atcttcgtca ctacttcggg atgtttatcg
     2701 atgacattgg ttgtttccga caaatcattc gccaaattat ataaacgagc ttcaccgact
     2761 tccgtatccg ggaagtgagg gcctttgata cgttccttca aaggtaaatg atacttccag
     2821 tttccccaac gtaccgcctg taattgttgt ttctggtaat aatagaaagt ctccgtgggc
     2881 gatgccatcg attctccctc caagattcca gacacattat gcccatctat cacccggtcg
     2941 gaaggaaccg cataaccgca ataatgcgcc aatgtcggta agaaatccat cgaagtcacc
     3001 agattatcag tttcctgtcc cgccggtatt ttagcgggcc atctcattat acaaggcacc
     3061 ctaaacccac cttcatacgt cgtacccttt tggcctctca acggacggtt cgtaccaccg
     3121 aagtgttcat ccgcaccatt atcggaagta aagataatca aggtattttg atccaatcct
     3181 tcctccttta aagtctcaag caagactccc atcgaccaat ccaattcctc ggtcgcatct
     3241 ccatagagtc cgttctgaga ctttcccttg aaagcgggag aagccgctaa cggattatga
     3301 gtcatattat ggcacaagta aataaagaac ggagattcct tatgagactt tataaactcc
     3361 acagtcttat tggtataacg aatcgtcaag gaatcatgac cgacaggagc cactattacc
     3421 tcctcctgtt ccatcaaggg taacggacaa tacggacgat ccatatcgtt actataagga
     3481 ataccataat agtagtcgaa accctgccgg gtaggaagaa atggcaattg atcccctaga
     3541 tgccatttcc cgatacaagc cgtcgcatat ccctgctcct tcatcaactc ggcgatcgtt
     3601 atctcaccgg gattcaagcc tttatgcgaa gctggaaata gcacttgcct ccctttggac
     3661 atcaaaggtg tagggtccgc atttacatgc atggagactc gccttggata acaccctgtc
     3721 aataaagccg atctggaagg tgtgctcacg ctcgaaccca cataaaaatc ggtcagtcgt
     3781 attccctctt tagccatctg gtcgatatgg ggagtacgat gcttcgtact cccgtaacaa
     3841 cctaaatccc catatccgaa atcatcgata aatacgatga tcacatttgg cctttccgcc
     3901 gcttgagtag ccacggccgc tcctgaaaag gctaataccg atattatgtt agatataagt
     3961 ttcatttcat ttttctttta gttgcacatt accaacccgg attctgatcc aaattcggat
     4021 tcaaagaacg ctcgctatca ggaatcggta ataaatcgta atattccaaa tagccatttg
     4081 ggaacttcgt ctcgatcacg ctaccctcat gatccttaat aatcataggg taaagttcct
     4141 taccgatttt ccaacgtttt acatctgacc aataacgtcc ttctaatgct aactcaatcc
     4201 gtctctcatg tctcactttc tcacgagcct cctcacggct catagatgtc ggcagcaaag
     4261 agatcttaac gtcatccctt tccgtacgga tccggttaag gatagcgatc gcatccgcca
     4321 catttccatt cgtctcaata atcgcctccg cttttgacaa taagacatcc gcatatctca
     4381 gtatgatatc attgatataa gactgcccgg aaggaggaag ctttgactca tcctgaatcc
     4441 gatatttacg ggtacttaaa tgtttcaacc gattaccggc atgattaaac gcacctcccg
     4501 gatacaggta attagggaaa cgatagccca agaaataaga acccggaagt acagccgtga
     4561 aacctaaacg aggatcccgg ttctcataag gattctcggg atctacagga gagccgtcga
     4621 tcgtctcata agccgctacc aaatcatccg tagggacata acggcttcca cgggtccaac
     4681 ttccggtacc cgttccgcaa tactggtcaa tataggaacc ttgcgaattc tcgccttcaa
     4741 tatattggat atcaaacaat acttccttat tgttctcatt agccggatca aacaaaccct
     4801 cataactatg gaatagacca tatttcttca acgcatcaat ttgctcgaca caagacagaa
     4861 cctccttgta tttaccttgg tataagtagg ctcgcatttt catacctaaa gccgccccct
     4921 tggtagcacg ccccggctca ggagcatcca ctcccagatt ggtgatcgca acctcataat
     4981 catccagcgc ttgttgccaa gtctcctcca aactcgcccg cttcaagcta cgagcttctt
     5041 ccgtggaaat gtccgtcaat ataataggta ccccaccata ggtttccgct agcacggaat
     5101 aagccagtcc ccgtagaaaa tgagtctcac ctgaatattt ggctttcgct tcttccgata
     5161 aatccactaa atccatacag gccaacaaat agtttgcccg ggagattatc tcgtaacatc
     5221 ttttccaacg atacgttacg actcctccgt cactagagct caatcgcccg gcacccaact
     5281 tattaaaaac ctcatccgtt ccccagttaa atgcgttagg ggtagctcca tccgttatgc
     5341 caaagccaaa caagccttga ttataaacct ctttttccct caattgagca tagacaccat
     5401 ttaaaaggag tttgatatcc gattcatttt ccgggaaact cgccgaagta atcttatcct
     5461 caggatacaa atccaaataa ttctccatac atcccgtgaa agagacacat agtataattg
     5521 ataagcaata tgctaataac tgtttcatac ttttagaaat taagatttat accaaatgta
     5581 aatattctcg gagtcgggta ataattggta cccgaatcaa acgtatttct ttccggatca
     5641 tatccttcat accctttttt ccacataatc gtaaacaggt tctgggcatt cgcatataca
     5701 tacaaccgtt gcatttttag ctttgaggta atccattcag ggaacgcata acctaattgt
     5761 aagttcttca atttcaagaa atcgatacga tgtacccaaa atgaggagtc atacgtgtcc
     5821 catgaagagt caaaccgaag catcggtata tttgagtccg gattctctgg gctccacgca
     5881 tcccgccatt tatcagaaat agtcagccat tcgtattgca tacgggtcat gccgctcttc
     5941 gtaaacgcat tcgcctgtcc caaaccttgg aataagatat ttaagtcaaa ccctttatag
     6001 cgtaagccgg cagtaagtcc atacgtaatt ttaggaatcg tattaccaag tatttgttta
     6061 tcttgatagt ctaattttcc atcgttatta acatcctcgt atttcagatt tcccatttcc
     6121 ggcttaagcc cattgctatg catatgttga gcggcttctt cgtccgattg atagatgcca
     6181 accgctttat agccatacaa agccttatac ggatatccct cacgaatcaa ataaagctgg
     6241 tccggagagt ttcctccttg aaatttcgtt actttattat cgatatacgt aaagtttagt
     6301 cctacgttaa atccaaggcg atctctgctc gtctcaagat tatcataatt cacgactaac
     6361 tcaaaaccat tatttttcat ttcgcccaca ttctcaaacg gcgcggtctt atcccctaat
     6421 acgtttggta ttggcaattg aacgataata tcggttgtct ttttattgaa gtaatcagct
     6481 tcaatattca acttattacc taagaagccc aaatccacgc caatatccaa ggaagaggta
     6541 gtttcccaag taatatcctc atccaccaaa gcggttacgg cagcacccgg tgccaacgaa
     6601 cctccataat tataactcaa gtcataattt tgggagatca ctgttaaata aggccaatat
     6661 ccttcaatgg tttgattacc taattgtccc cacgacgcac gtagtttcaa attagaaaac
     6721 agattcaggt tcttaataaa cgcctcttca ctcaaacgcc atcctgcaga gaaacccgga
     6781 aaaacacccc agcgatttcc ccgtttaaaa cgagaggagg catcggcacg gagattcatc
     6841 tcaaataaat atttatccgc aaaggcataa ttcaatcgac caaaataaga tgccatgcgt
     6901 agaccttcaa aatttccctc tcccttgata ccttccgttc ccgcgtccac ttgggttaat
     6961 ccttctttgg gtgggttggt tcttcgggca aatacgttct ttatactgta attctccaat
     7021 tgggtaccaa ggatagcggc aacataatgc ttatccgcaa atcgcttgct atagtttaat
     7081 gtcgcttgga aattattacg catggtcgat acttgctctc tactcaacac aataccatca
     7141 cgattgtaat ttttcggtat cgtctctatg ccagaatccg tatatccata aagggtctca
     7201 ttatatttat cgaccatttt ccaattgcca ttagaggccc atgttacttg taagttcaag
     7261 tctttcgtaa aatctacggt agcgaaagca tttacagcca tataatcctt ggatgtttta
     7321 gtcgccccgt tcgaagcgtc tataaccggc tgataagtcg tatacaataa agtaccatca
     7381 tccttaatcg cttctaccga accgaaacgg ccatcccggg tatatggagc gatgaaagga
     7441 gccgcgcctt gttgctgttc gaatacacgg aacaaatcaa aaggctcttg ggaattccta
     7501 cgagtataat tcaaacgagc gccaactctc aaccatgaat tcactttata ctccacattt
     7561 gcccggatac cgaaccgctc cgccttagag ttcatcaaaa taccttcctg actcaaatag
     7621 ttcaaagaca agaaggaaga tagtttctcc gatccaccgc gaatggataa attatgccct
     7681 gttattaaag cattccgata aagagagtca taccaatccg tattcgggta tttataagga
     7741 tctgttccat tagcgaaatt agagatcaat gtttccgaga aaagagggtt ctctccccca
     7801 ttcaccaaag cttgattcgc catagtcata tgctcggcgc tattcgtcac taaatcaaaa
     7861 tgacgtccga tctgctgcat tccgacgtaa gagttcaact ctacttgggt tttctcatta
     7921 ttctttccca tcttcgtcgt aaccaaaacg acaccgttag cggcctttga tccgtaaata
     7981 gccgcactag ccgcatcctt caagactgtg atactttcga tgtcactcgg atttacttgg
     8041 ctgaataccc cttctactcc gtcaataatc accaacgggt ccgaattatt caatgtaccc
     8101 cagccacgaa ttctcaattg cgctccatca tctcccggct tacccgaatt ctggctgatc
     8161 cacacgccgg aaacctttcc ggaaagtgct tgagaagcat ctgtgatcgg acggttcgtc
     8221 aattcctcat caaatttgac tgaagaaaca gaacccgtca aattcacctt cttctgggtt
     8281 ccataaccaa caaccacaac ctcttccaaa gcctgtgtat cctcccttaa acgtacattc
     8341 aatgaagtct gtcccgcaat agcgacagtt gttggcataa agccgatata agaaaattga
     8401 agtgtcgcat tatccgatac ctccaaaata aatttaccat caaagtctgt tatcgtacca
     8461 tttgtagtac ctttctccac aacattcgct ccaatgatag gttccccttt tgaatcgaca
     8521 acaacacccg ttattttttt ggcttgctgg gtgaccgcat tcgctatagg tttttcaaat
     8581 aagtagatct ttccattttt aacttcataa cttaatgacg tgccctccgt tattttatcc
     8641 aatacatttg tcaattctgc attcgtaaaa ttaacgctca ctctccgatt caaatctacg
     8701 atttgtttgc tatacgcaac actcaacccg gtttggtggg tgatggtagc taaaactttc
     8761 tccactttcg cattgtccag cacaatagaa acccgctgag ccgaggcggt agccgtgaaa
     8821 ctcagcaagg atatgactaa aaatagaaag gttaacttca tggcattcgg tattttctca
     8881 attaatatta aaaggcacct acgccgaggg ctttcttgct tttctttcat atatttgtat
     8941 tgattttaat agttggtatt agaaatttat ttttaatacg atcggcagcc gaaaagggta
     9001 ggagcttttc ggctgttctt atgttatcta tttatgagga atccatacgc atatctattt
     9061 taaggttaac actctgtttc ctgctctcct atcaaataga cacacgacaa atctaaaagg
     9121 atgagtcgtt atagctaatt tttttatttt ttcatccgga cttctatctt gccccctttt
     9181 tcctcgaata gtacaggcgt gattttttcc aattctttta ataccgtggt caaattgacg
     9241 ctatcggtcg ttatcgtata cgtatatcgc aaagcggcag aatccttcac gtcaaaggat
     9301 atatcataag ttcgagccaa tgttttcatt acgtccgata aaggggcgct cttaaatacg
     9361 agcacattac gtctccatgc cgaatacatc ttgacatcgt gggaacggag tacctcacaa
     9421 cgtccggaag ccttgttata aaccgctttt tctcccgggc gtaattgata agatttgaag
     9481 gatcttgatt tcaactcgat agatcctgtc tctaaagcga cgaatatagc ttcttcctcc
     9541 ggataggctt tcacatcaaa ggtagtaccc aacactttta tatccatata agaaagatcc
     9601 acgataaaag gccgattctt gttcttggcg acctcgaacc aagcctctcc ttccaaataa
     9661 accttacgtt cggagagacc gaattttttc ggataacgaa tacggcttcc cgaattcaaa
     9721 tggaccttac tcccatcttg aaaaagcact tgcatgcgtt ccccattagg tacgtacacc
     9781 tcgtcatagc catcatccgc caacaaatcc acttgtgagt ttatgcgtat gaaaagtcct
     9841 ataattaaag cgatcggtat aaagaccgca gccgcatacg ctataaaacg gcgtattttt
     9901 tgtcggcgga gttgccgcat aatattctga tacattacgg ctgagggtat cggatggtcg
     9961 atccatgcct cttcctcccc catatgaatc gttttctcat cctgatcgat acgctcagca
    10021 agccatgcct gtccttccgg ggtcttaaac caacgaacaa cctcacaaga ctcctcggaa
    10081 gtagcctcat tatttagcgt tttctctatg atcgatagat cgggtatttt catattcatt
    10141 ttcttttatc aattgacacg caaagccatc aataggatga gttccacaaa tataaaagaa
    10201 ataaaaatag tctctcgaaa tgtgcccgca gtatttttat cgcttgcgca taatgtgttt
    10261 ttaccgtggg gaccgagata ttcatcttat cggcgatttc ttgattagaa agattccctt
    10321 tcagcttata cagacagact tggcgtttct gctccggcaa gtgatcgatc gcttggtaaa
    10381 aatgagacat catatcttgt tcctctatct ttataagcag ttcatcctca tattccggcg
    10441 ctgattgtac gatctcataa tttttctcta cggcgctatt attattccgg atctcattta
    10501 atacgtgatt ctttagcatt gtatagagat agttccttaa attcacgttc accatcagta
    10561 gggaacgtgc ctcccacaat ttcagaaaaa cttgctgtac ggcatcttcc gaagaatatg
    10621 tacttttcaa atatttatag gccaacacat acaataattt atgataccgc tcataaataa
    10681 cagtaaacgc atcctcgctc ccctgcctca atgaggtgag cagatcttca tcgctccgta
    10741 tggatttctg aaaaaaagac attcgaggag actatataat atacgattcg ctatttaaca
    10801 gacgttccgc ttcctccttc atggcatccg gcacctgtgt aaccgcacct tcactgatcg
    10861 atcggataaa ttccggatac tctctacgat aaacatccaa catccggttc gcaaaaacaa
    10921 acatcatcgt atattggata ttcgccagcc gatcacatat ttttataaaa gaagcgaatt
    10981 tagtctgccg tattccttga taatacaggt cattcgcccg ttctccccgg tttcgtcctt
    11041 tttcattcgt taaggcgtat acgatttccg gaacttggtc ttccaagtgc tgtctcacgc
    11101 cttccggcaa gacaaagcct ccccccttga actctttcag gaatttcacg acatcattat
    11161 aggtcatccg tgcatcttct atcgtatcat gcagaaaagc agaggcatac aaaatcagta
    11221 tatccgcctc ggtctcagct accagatatc cgtagcgaga gacatacgat accgtcattt
    11281 tcagatgaaa tccataaggc aacacatgat catatttctg attcacatca tcatgtatac
    11341 gaaaagcagc cttctccata ctgcagatcc aaggataata acgctttact agagcgataa
    11401 atgattgttt ttccattctt tcgatactaa agattaatct ttacgcatgg caataataca
    11461 cagttccgaa accgctgttt ccgaaacggc ggtttctaca atgcgaagat atataaataa
    11521 tcgaattaaa tcactctata tcaaattatt taatacggac tcccacacgt gcaagtgaaa
    11581 cataccgttt cctttcttta ttatggatat aattattata tttgcaataa aatgtattta
    11641 tattatggag acaatcgcaa tgatgaatcc ttttgtcgtg ggtagatatg tatcagacaa
    11701 atatttttgt gaccgtgagg gagagacaag cttcttgatt aaacagattg agaacggacg
    11761 taatgtcgca ttgatttctc cacgccgttt gggtaagacc ggattgatcc aacatctttt
    11821 tcatcaagaa tcgatagaaa aaaattatca tgcgttcttt gtggatattt atgccactac
    11881 ttcattaaca gagttcgtat atctattagg aaaagccatc tatgacgaat tgaagccaaa
    11941 gaaaacggtt tggacggaac ggttctttca aatcataacc tcattgcgtg cgggttttaa
    12001 actggatatg gtaaccggag aaccttgttt tgatattggg ctaggagaca ttcaagcacc
    12061 acaaacaaca cttgatgaga tcttcgctta tctagagacc gcagataaac catgtatcgt
    12121 ggcgatcgat gagttccaac aaattggcgg ctatgaggag aaaaatgtag aagcgttgtt
    12181 gcgaaccaag attcaacaat gcaagcagac tatgtttatc ttctccggca gtaaacgcca
    12241 tttgatgagt aatatgttta attcctcttc caagcctttt tatcaaagcg ctattagtat
    12301 aggacttgag ccaataccca ttcatatcta tgtggagttc gccaaccggc tttttgagca
    12361 aaggggaaag cttattgaca aatccgtaat agaagaagtt tatcggatgt tcgatggcta
    12421 tacttggttt gtgcaaatga taatgaacga acttttcgca ttgaccgaag agggtgagcg
    12481 ttgtagtatg gataagatag aaatagcccg caagaatgtg attctaacac aagaaagtag
    12541 ttacaaggat ctacttgcca atcttgctcc caaacaaaaa cttgttttac aagctatcgc
    12601 caaagagggc agagcagaag gtctcacgtc atcagcattt atcaaaaaat acaagctacc
    12661 ctcagccagt tctgtacaat ctgcggtcaa acctctgttg aaaaatgatt tgataacaca
    12721 ggaagatggc ttttataggg tatatgacta ctttttcgcg gattggatgg ctagaatata
    12781 ttgactctct tgtatgtaaa tgtcagaaaa taagcaaatc ttagtaggca ctatccgtta
    12841 ctgaagtaaa taatttacga cttgaaatgt aaattcctta tgcggtgaaa atgaattatt
    12901 tagacaacat acttaatcgc ttgcaaaagg cttctcaagt gattagttat tcacttccca
    12961 agccgttann nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    13021 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnaa ccatcaaata
    13081 atatccagcc gttctctcag ttgtttaaaa tagcgatgcg aggcgatcct ctcctcctct
    13141 tggaaggggg gatagaactc gcatcgtaag gtcttattct cgatgaacat caaataagtc
    13201 aagttcacaa tgcaatcttg gcttatttga acaaacgtat tattgataga caacaaatct
    13261 ttcgctgtcg tgcccatttt tagtttatga gtagtacggg aagtcaagac aatctgccag
    13321 caacgctgat ctcccaagaa ctgaaacagg aatatctcct cacaacggac tagcaaaaga
    13381 cccgaaacgg tttggatcgc aaatcgacta tcccgattca atattttccg caaggatctc
    13441 tccatgcagg caacatccgc aggctctgtc gtatgaaaac gttcgataag tgcctctaac
    13501 tcctcaatca aatacggttt taacaaataa tcaaacgcgg aggcacgtag ggcatccaat
    13561 atatatttat cgtataccgt atagaaaacg actctcaagt tcggaagaat atcatcccgt
    13621 atatcatcca gcaaatcaaa gccagacatg tccggaagtt ccacatccaa aaacaccaaa
    13681 tccggttgat acttaaggat atgcctcttg cccaattccg ccgttgtcgc tgtatccaat
    13741 atccttacct ccgagaaggc caatagatcg ttttgcaatt tctggatcga tccaaggtca
    13801 tcatctatga ttattactgt tatttccggt tccatacacg cttccatttt ccaacaaagt
    13861 aaaatattta ttgttaagat aaaaaattaa cggcttacca taaatagtgc tttttacgta
    13921 taagttgtaa tattcacgtt tatcctatcg tttttcatgc ttatctgtca ttttttattt
    13981 tatgatcttg gttaattacc attgattgat aaaccctatc tttgcaaata cagttataaa
    14041 atagaaacaa tatatttatg tctcgaaaaa taaatcttat tatattcctc tgtttcattt
    14101 tatgcgaggt atatgcccaa tacgtacccg atgtattggg agatggctat ttacgccgta
    14161 ccttccagat gccggatgat tatgagggga aggtagtttg cacgctggtc aagaaacctc
    14221 aactggatag cgtaaaacag gccgtgctgt atatccatgg ctataatgac tattttttcc
    14281 agaaacaatt aggggatagc gtaaacgctc acggatataa tttctatgcg atggacttgc
    14341 ggaaatacgg acgttcgata ttacccaatc aaaacccgtt cttttgcaag agcctaaaag
    14401 agtatttcgc tgatatcgat accgctttag ccaccatcca gtccgaaggt aatgaacgga
    14461 tattattaat ggcgcattct acgggcgggt tgatcacacc ttattatttg aatagcaaga
    14521 aaggggagtt accgatagac gggcttatct tgaacagccc ttttctagat tggaatttcg
    14581 gatggtttat ggagaaagtc gtactgccaa ccgttgcgtt tgtcgggagg ctatttccga
    14641 atcttaccgt acaaggtttg ggtgatccga attacgctta tagcctgctt aagcagtata
    14701 aaggagaatg ggaatttgat acgaactgga aaatgatatt cgggcatccg aaaaaagccg
    14761 gatggatcaa agccatacaa gaagcgcaac agacggtaca aaaagggcta aaactggatt
    14821 gtccgatact agtgatgtct tccaacaaat cttttccgga gacagagaca tggcatgagg
    14881 aatacatgac ctccgacatc gtcttggatg ttcaagacat tcaaaaatac ggggagaaac
    14941 taggagacaa agtcacgaga gataccattc caaacggcat ccacgatctg atcctatctc
    15001 aaaagcccta tcggaacgat gcctatcaaa ctatattcga gtggttaaag aaacaataat
    15061 ggttgcacca aacatataaa tccttacctt tgcgcccaga caaaacattt atatatacat
    15121 gaaatcagtg cgatcaattt ttataggtct gacttgtctg gggatggcaa cggctagttt
    15181 cgctcaagaa gaagagacaa ctccggaagc gactacctac aaggccgaaa tattcggatc
    15241 ggtagctagt ggcgacaatg cccctttctg gatggttagc aatcgatacg gaattgttcc
    15301 tttggaagcg aataacggat atttgaatgc gggagtattc cataatcaaa cttttggcaa
    15361 aggttttcgc tggggagccg gattagacgt agtggccgca gttcctcgtc atcgcaattt
    15421 ctttatccaa caaatatatg ccgagttagg ttacaaatgc ttgctattga gtgtaggaag
    15481 caaggaacgc tataattcac tttgggatcg ttggcttagc tcgggcgata tcgtgcaatc
    15541 cgccaatgcc cgcccgattc cggaagtgaa catcagcatt ccggaattta ccgtcgttcc
    15601 tttaactaaa ggctggatgc aagtcaaagg agactttgcc gtcggtcgtt ctttcgacaa
    15661 ggattatctg gctaacttca caaacaataa gcagacttat gtagataacg ttttatggca
    15721 tcataaatca ttatttgtac agattaagga tacacgcaat gacttcccgt tatccggtgt
    15781 aatcggagta cagcattggg cacaatgggg aggaacctca accaatccta agatcggaaa
    15841 gcagcctcaa tccatcaagg accttatccg ggttatttgc ggcagcgaag ggggtggcga
    15901 cgcaacagtc tccgatcaaa tcaacgtact gggtaatcat tatggctctt acgatttcaa
    15961 attggctttt acacaaccta actggcaagt atccgcctat taccaacatt tcttcgagga
    16021 taaatccggt atgatattcg taaacaatac cgacggatta tggggaggac aattggattt
    16081 accaaaattc ccgtggttgc gtaaggtggt cgtggagtat ctggttacaa gagaccaaag
    16141 cggacagttc cacttcatcg attttgatca cgacctacat cccggcgtag gtggcggtgg
    16201 tgatgattat tataacaacg gagaatacac taccggagcc tcttatttta accgggcgat
    16261 aggttctcct ctgatcccaa gtccggagta taacgagaac ggttcattag gattcaagaa
    16321 caaccgtgtt cgtgactggc atttcggtgc ggaaggcgct atctcctcac aagtatctta
    16381 tcgggtatta gtcaccgtga tgaatagttg gggtagacat gccacccctt tccttagcaa
    16441 gaaaagagga gcttccggac ttttagatat ctcttatcaa catccccgtt tatcgggatg
    16501 ggaatttaca gggtctttgg cagctgatgc cggttccatg ttcggcgata acttcggatt
    16561 cagcctgaaa gtagcgaaac gtggcatctt gaaaagctgg aaataataac ctaaattatt
    16621 tatattcttc ccacaaggca gatgctatga tttcttgagt ctgatcagcg aacgcttgca
    16681 ttcctttgtg ggaagtgtct atattctcgg tagaaaccgc cggatggatc accatctcca
    16741 tccgatgacg atggacattc aacgacccga tcggcaagac atcaaacggc ccgtttaagg
    16801 tgatcggaat aataggcaaa tgctgatcta gcgccatttg ataagcccct ttcttgaaac
    16861 ggatcatttt cccggtatac gtacgcgaac cttccgggaa aacaaccacg gaagccccgt
    16921 tccgaagaca acgctccgcc tccaaaacac tacgagcggc agccttcggc gtagaattat
    16981 cgacaaagat aaaaccggcg gcacggcaag cggccccgac aaatggaatt ttagcgatac
    17041 ccgccttcat cacccactta atgggaacgc ctaagaaacc atatatcaag aaaatatcaa
    17101 acgcaccttg atgatttgct acgaaaacat acgattgttt ccggtctata tgctcacgcc
    17161 cttttaccgt caccggacaa agcgccagat agcaagtcaa tcgagaccag atcatacccg
    17221 gataataagc gaagattttc tctcccccca atagacaacc gatgataacc gttacagccg
    17281 taagtatagt cagtaccaga aatacaggta caaaaaacag ccacaaataa actatgtaaa
    17341 gtattcttcc catacgtaac tatattataa cacaaatata gaagctaatt tcaatcgttt
    17401 cattattttt ctccgaaaat attttcacga tcgggttatt attgctttat ttgcggtaga
    17461 aaagaaaata attataaaat atctataacc atgaatgagt taattaaaaa tctaggagtg
    17521 atcgtactca ttattggtgc ggcagttttg gctgtaccgt ttttcaccgg tggtatgaca
    17581 aatagtattc tacttacagg tctgggattg gttctccttg gctattttgg tcatatcgta
    17641 atcaacaaac gagtagaata atacacgcta cttagattta aaaggaaatg aaaaaggatg
    17701 tgcctcattg ttacgcacat cctttttttg aatcatcatg caaattgaga gatatgccca
    17761 aatcgttatt gagttcccca ttccttgttt ggtttatcgc caagccataa ttccaaaagg
    17821 ccaccttgct caaatacggt atgcggcaat tgatatttat gatacatctc tccgttcaaa
    17881 gaagctttct ggatataaca attctctggg gagttatcat gtactttaat cttaaactcg
    17941 ttccctttat aataccgaga atccaatcga atcgtaatct cattgaaaac agggcttgta
    18001 atatcataca tcggattata ggcagagcct ccatccaaac tgaataatcc catagccatc
    18061 agtgcactta ttccagccat ctgtccttga tcttcatcat tttcgccgta gcctcgctct
    18121 ggcgtaatat caccataggt ctgtttagcg acctgacgca cccaatattg agtcagccaa
    18181 ggctttccta catgtgagaa aacgtgcgca ttcgagcaac cgggttgatt ggcataacta
    18241 acataactag acaggaatct tgcatttttc gacatctcaa acacataatt caattgagta
    18301 gctaagctgt cattacctcc catcaaacga gccaatgttt caatgtcatg agataatcca
    18361 aaagtagcct gccaagcatt ggcttgtaca aacccacgct cggacaaagg atccaaatgg
    18421 acccactctc ctgtttcttt tctaggcatc atcaacctca aatccggatg ccaagacgca
    18481 ggccagccca aggaacgatt tctataataa ttataatcct tgagttttcc catagctttc
    18541 gccatttctc ccaaagccca atcctcaaag gcccattgaa tagtcaagcc agcctcttct
    18601 gggcaatatc catgtttaat atagaactcc aactctttat ccatatcaaa ggcaagcata
    18661 ccacctttct catgattcct tttcatagcc gcatatccct ccttgggcga ccatttatga
    18721 aacacccccc gctgataagc ggaagtaatc aaggaggtag ccggacagcc cgtcataata
    18781 taagtataag accctatgga cggcccacga ggtaatagac ctccattctt gtcatattcg
    18841 ataaaagaag cggaaaactc gtctaaaaca gaaggatacg ccagtcccca caacgtgttt
    18901 aaattccact gtgtcaacca tagagcatct gaattataca tatgaaacct tgattttcct
    18961 gttttatctt taggcaaagt ccgtacttgg aatttaggag caatcgtatg tatccttgtt
    19021 tgttttccaa tacgttctcc tccggacaaa taatccggat actcgccatt gctatcatct
    19081 atcttatgac gccccaacaa tacgtgccac aaatcggtat aaaacttggt cttttgctga
    19141 aaagaaccac cttgcacatc aatttttccc aaccactcat tccaaatacg ctcggacgca
    19201 ctcttaactt gatcaaaatc ccaatgttga cattcccgct ctatattctc acgggcattt
    19261 tcctcactca cataagagat agcggtcttc aacaatagct catcaccagc cttaaaagat
    19321 ccaaaacaag cttctacgcc agaagaagga gattgtttaa aagaagactt aggcacggta
    19381 attaattctg gagaacctat caaactattg atatccgttt cctttctatc tccaacccaa
    19441 ccgttcaaag catccatagg tttatcaaat tgaacaacaa aataaacttt agccacatcg
    19501 acacctcccc atacacgacc agccgtatca aaatatccgg agatctctgt atcattcacc
    19561 tttgtcacat gagcgttcaa caaagtagaa gtagctatat gacctcccag atttaccaag
    19621 accttcgcca aaccatcttg cgtatacgta aaacgataaa gtcctaccct atccgtaacc
    19681 gtctgttcta cccatatttt ataagtatcc aagaacaaac ggtgataacc aggttggaca
    19741 atctcatcat catgagaaaa agaagaacgc caaaccttat ctcctctgca aacatctacc
    19801 tcatctttca ccggcatcaa agacaatcct gaaatcatcc aattatgaat ttgagggaag
    19861 cctaaaacct tagtagaatt ataattataa cctcctcctc cttgattgat attgcgggtt
    19921 aatggagcgg aacttatcat accgaaaggc aaacttccgg tcacaaagaa aaaatatcga
    19981 cctttagcgg tctcgacata aggattcacc caagagatat aatccggata agactcagga
    20041 gcaggataca cctctatctc agacagccct aaatcttgtc cttctccatc cgtcatttga
    20101 aaacgaatcc attccgtctt ccgagtatca aattcaacca cccttggcgc tccatcattg
    20161 ggaatcaaat taaccgttac cgaactaccg tcactaaaga acaaggtacc cgcagcacaa
    20221 tggcttcgct catccacccg atcgtataaa ataaccttat tcgtataaat cgcatgatcc
    20281 caatctaatt gtatccaagg atacggatac acccgaccac gcgcatccaa ttttgtcttg
    20341 gctacccatt ctccctttcc ggaaatacga atcacctgat ctatcacata cttaccttcc
    20401 tgctcttggc tcaaggcaga cgaacaggaa actttagctt gataagcgac attatgaggg
    20461 gttgcccata actcataaca ggtagtcaaa cacaatagat ataaaataac tcctagctgc
    20521 ttcatatttt ttattacatc gtgaaaaagc ggtgcatcaa atggatatta aactatttga
    20581 cacaccgcct tttctttcat ttaatttatc aataacccgg attctgtttc attacttccg
    20641 taccacaaat atcaatcata gactgaggta tcgggaaata ctcatgctta ccttttacga
    20701 aatgagcatt ttgcaagtgg gaacggaaca ctttctcttt ggcgatataa gcgttgataa
    20761 cttcatccgc gacaccccaa cgcaccaaat caaagaaacg aattccctca tgcgccatct
    20821 ccaaacgtct ctccatacgt aacgcttgca cggcttcatt ttttgattta aaaggctcat
    20881 cataaacccc taccttataa ttagcagcat cttgtgattg atccattgtc ttgacatgct
    20941 gagtattttt cgcacgctcc ctaatcatat tgatatactt acgcccagtc tctaaatcac
    21001 ctgtctcaat agcagcctca gctctccaca ataacaaatc cgcataacga atcacataga
    21061 aattcaaagc attcacataa ggccatatcg gcgaataata agtagaattc aatgaaacca
    21121 aacgcttctt cgggctatac gggccataca cactagcctc tctaggagtc caatcataca
    21181 attgtacatc cataaacggt atatttggtc tagctaatgt atgatccaaa cgaacatcta
    21241 catagtcatt ctctgacaca tctttaccat cattataagg caagccttta acatccgttt
    21301 tataagcatt taccaaattt tgagtcggcc gcaaaaagcc atatacagga taaggacctc
    21361 ccggaggcaa caagcgatcg ccataacttc cgttctcatt attgggagaa ccatcattaa
    21421 tggacagctg gatcgcaaag ataatctccg agcaattatc attttcaggc aagaacacat
    21481 tccggaaatc agggaatagc tcatattttc cagattgaat cacctcatca caagcttcca
    21541 aacattcttt ccacttggac tgatataaat aaacctttgc catataagct ctagctgcca
    21601 ttttagtagg ccggccataa tccgcttggc tctccggcaa tactttataa gcagcagaga
    21661 actcttctaa aatcttctcc cacaattgat cggatgaaaa ctcgatattc gatttcttat
    21721 tgtattcatt tggatccacc aacgtttcat cgatccaagg aatctgatta taaatgattt
    21781 ttaagttgaa ataataatgc cccctcaaaa agcgcatctc agctaaacgc tgttccttgt
    21841 ttttaacctc actaccattc aataaacgaa tcgcttggtt acaacgtttt attccctcat
    21901 aaagagcagc ccatcgagct tcaaagtcaa tccctgtggg attcgcatta aagatctcca
    21961 tcaaatggat ttggttctgg tcaccggtac cgccgccacc tttatacgca tcgtcagaga
    22021 caacatcccc gaactgccag tttgagcaac cggaattaat cgcatcagag gcataatacc
    22081 catccaacac agcatatgca ccggtcacga taccctctat attttcctca ctctctacct
    22141 gtccgggcaa gaactcaccc acaggctcct cagaaaggaa tgagtccgca caagaacaca
    22201 tcatcaacgc tgatgccgca aaataaaata tctttttcat tgtatatatc tctttttatg
    22261 ttaaaaacta acgttaaccc ctaaagtaaa tgttcttggt aatggataca ctccacgatc
    22321 cacccccata tccaaattac ggttctcaga agaataactc tgcaaaccaa cctccggatc
    22381 aataccttca tatcccgtta tggtaaacaa gttctgtcct tgcaaataaa tatacgtacg
    22441 tttcaacttc aacttagatg ctactttatc cggtagtgta taccccacct ttaagttctt
    22501 taaacggaca aaagaggcat tatggatata ataggtagaa ggacgaatat tattattcgg
    22561 atcatccaat gtgacacgag gtatatccgt atccgtatta tccggacgcc aagcatccaa
    22621 gatcgtagaa tttttattat attgagcctg gttataaaac tcacccaaat aattcgtcaa
    22681 attatagacc tcattaccaa atacaccttg gaagaaggca ctaacatcaa agtttttata
    22741 attgaaaccc aacgtcaacc ccatgctaca atcaggcaac ggatttccct tgaaatcgcg
    22801 gtcatcacta ttgataacgc catctccatt caaatccttg aagcgaatat cacccggttt
    22861 cgcattcggt tgtaataact cacctctatc attcttatag ttttggatct ccgcatcgct
    22921 ttggaacaga ccatcagcct catacacgaa gaaggatccg atcggttgtc ctaccgctga
    22981 acgagaagtc tcttgatcga aattacgtcc gtgaagttca ctactggaaa gacctatata
    23041 atccacccca ttcagttcgg tcattttatt cttgataaca gagaagttat atgcgacaga
    23101 gaaaccaaaa tcctgattga tttgcttttg ataatttatc tccatctcaa aacctttgtt
    23161 gttcatctta cctacattat cccaaacagt catatttgtt cccccgatcg aggcaggtaa
    23221 ggctctacgc cacaataagt ccttggtatc tttattaaaa tagtccaaag tcaaattcaa
    23281 gtcaccattc aaaaaaccca aatccacacc gacattcgtt tgtgtggttg tctcccattt
    23341 caaattaacg tttccgtttc gagtctgcac caatcctaga tctacaccac tttgatttcc
    23401 atcaatcggg taattcgagt tcgtagaatt actcttatat gagtcaatcg tcgcatacga
    23461 cggaacatcc gagtttccat tctgtcccca accaacgcgt actttcaaat tactaattgc
    23521 ctcaacatca aaaaacggct cattactaat gcgccatcca actgatgccg cagggaaatt
    23581 accccatttg ttattaccta aacgagatga accatcccga cgcaaagtaa acgccaccaa
    23641 ataccgatca tgataattat aatcgagctt accgaaataa gagaccatac tatactccgt
    23701 agcagcaccc gagttcttct gggttcctac atctcccgca tctaaaaaaa ggaagttagg
    23761 atcgtctgac ggaaaaccgt ctcttgaagc tgtaaaatac tcatatctat ttctcaaaga
    23821 ctccatacct aataaggcat tgatcgtatg gtcgccaaat gtcttattat aagtcaaggt
    23881 attcgtgaat acccagttaa aattccaagc atttcggttg gataaactac ttaatttctc
    23941 cgaggcattc aactcatcat attttggact gaaagaacgt ctatacagat tattgtaatc
    24001 aacaccaaaa gaggtcttaa acataagccc atcgaacaaa tgcaactcgg catacaaatt
    24061 acctaccaaa cggctcttct tatcttgatt atccttgttc ctatacaatt tacccatagg
    24121 attcggaata tccgagaata catttccggc atactcatct tccagatttt tcacgggcgt
    24181 gatagactgg aatttataag cctcatacaa agttcctccc aaggcggcat tgttagagac
    24241 actagttccc caagaatgag aaagagagat attttctcct atacggaaat gatcatcaaa
    24301 caatttatac tcggaattaa aacgaccact cacacgctta aaatcgctaa acttaaccaa
    24361 tccctgctga tcatagtatc ccaacgagaa taattgatta gattttttat ccgctttcgt
    24421 aaaagagaga ttataagact gtactacggc cgcacgtaaa atctcatcga cccaatccac
    24481 gtcatcggaa gggattaaat gatcactatc caaatattca ggaacaactg cctgatcacc
    24541 atttccgtag atatcatgcg aaggagtttt tccatcattt ttcattgcct gccacaacat
    24601 atcgccaaac tgttgcgcat tcaacatcct caattgtttc gccgcttttt gtacaccaaa
    24661 gtaagcatct aaattgacat taaattcacc ctcttttcct ctttttgtat tgatgataac
    24721 gacaccatta gcggcacgag ctccatagat agaggcagag gaagcatcct tcaacacctg
    24781 catagattcg atatcgtttg gattcaagaa attgatacca ccatccacag gaataccatc
    24841 aatgatataa agcggatcat tgttacggat cgtactgaaa ccgcgaatac gcaccgcaac
    24901 tcctccaccc ggcatattat ccggcatcac gttcactcct gagagcttgc cctgcatcat
    24961 ttggtctacg ctagaaaccg gtgtatcttt caaatcatcg atcttcaaga ccgaaaccgc
    25021 gcctgtaaga tcttttttac gggatacacc ataacctacg accacaacct catccaagtt
    25081 ttgtgagtcc tctttcaacg aaatagtcaa atctgtcttt gatccgggta ctaattccgt
    25141 tgataaataa ccaatataag aaacaaccaa tacagcatta tccggaactt ccagcgtgaa
    25201 acgcccatca atatctgtaa tcgtaccaac agtcgttcct ttcaccaata catttgcgcc
    25261 aattaccggt tcttggttcg aatccaatac gactccttgt accgtatgtc cttgttgctg
    25321 cgccaaagga atagattcta atttatgcga taagataatc tgcttatcca caatcttgta
    25381 atcgacattc atgttatcga agacccggga taaaaccaaa ttaatatcct tattattggc
    25441 ctctaaatta acaacacggc tcacatccaa aacatgatcc gcatacaaga atgaataacc
    25501 cgtttcctcc tctatccgat cgatcgcttg ctccaacgta gcgtttttca acgacaagga
    25561 aagtgttgtt gtctgtgaat aagaggtacc tgcatataac tggaaggcag tcaagaatgt
    25621 aaatgccgta ccaagattta agatacgatt cgattgaggt aaataccgag taagattcct
    25681 cttacgtaaa tgaaatgcac tcataagcat gtagatttag tgattacaca aaatttattt
    25741 tgaaatgatt ttttatcgtt gataaacatc tatcctctgc cggacaaacg tggaatccga
    25801 atgagaggaa agttgtcggg cagaccattc aataggggca gtctgtttta gataatccaa
    25861 tatttgctcc aaggtctcat ttgtgaaagt cgcacggtat ttatactccg cattcgagtt
    25921 cttatgcagt acgatctcca cattatatcg tttttccagt cgctttagta ccttctctaa
    25981 aggagtattt cgaaatacca tccgcccctt tctccaatcc atcttctcat ccaaattgac
    26041 agcagaaaca cggaacacac cgctttcctt attaagcacg acctgtttgt tcggttccaa
    26101 gcggatccgt tcatcgttcc ggataacatc gatctttcct ttttccagca cagcctcgat
    26161 aaaaggttca tcgtcatagg cattcacatt gaacttcgtt ccatacgcta ttacccgcaa
    26221 tccctcagag gtagacacac taaaaggatg ttccggatcg gcttcaactt caaaatagcc
    26281 ctcaccaaag agctgaactt tacgttcttt ctcatcaaag accgatggat aaaccaagcg
    26341 gctgccggca ttcaaccaaa caacagattg atcaggtaac accaaacggg taattgtacc
    26401 aggcatggaa ctaatctccg caaaaaccac agatgccccc gtcttaacat tcctacctgt
    26461 ggtataatat aaataagaaa aaaataacga ggatatgagc aacggtacta caagaatagc
    26521 tgcggcacgg gtaaaaaaca acgaaaacat cctcatagag gctttccgct tagcacgacg
    26581 ttccatgctt tgccaagcct tatgcacatc tatcgcttgg tattctagca tatcctcaga
    26641 cagagcttta atcttctcaa tctgccgtaa tgtacttttt tcgtctccgc tttctcgcat
    26701 atatgattgt ctttttctat atagacacag tcaaaacaaa aacacgacag caaaacgact
    26761 ttttttatat ttttcttcct cttgtacccc acaataaagc aaggaaatca cctaagcagg
    26821 tattgcccaa cacgtatata tgtgtgggcc ctcctcacca attgcacaaa aagcaaggat
    26881 tttagcttgt gaaacaaagg ggaatatatt ctaaaaatat atacatttgt cccattatgg
    26941 aaagaaatcc aacaatgact gatatcgatt tccttttacg gcaaatcacg accgaggata
    27001 ataagctctc cttccaacgt ttatttgagt tatattatcc ggctctttgc atatatacca
    27061 aacgttttat ctctgaccgg gaaacgagag aagatatcgt acaggaagtt ttttcctcca
    27121 tctgggaaaa tcgtaaacgc atcgtaataa gaacttccgc gcgcaattat ctcatcacag
    27181 ctaccaagaa ccacagtctc aactatctgc aacgcaatca cgaagaatat gtagaccaat
    27241 tctctcaaga gcaaatccct atctatgcgg aaagtggcga ggagctttat acttgggaag
    27301 aattacaaac cctacttcga gaggcacttg ctaaattacc tgaaaactat cgatatgtat
    27361 tcgagaagaa tcgctttgag aataagagtt acggcgagat cgcggaggat atgcaaatat
    27421 ccatacggac agtagaaaga tataaaaata aggcgattga aatattaaag acagagttga
    27481 aagactactt gcccctgttc attggttggc tattttaaca aaaacttccg gaaataccca
    27541 catacctccg gaagtttctc gtcctcaatt tattgttgct ccaaccaaac cttcacccct
    27601 tcaagtaaga tctggttctc atcagacttc tgggtagaga gccgtagata agtctcatcc
    27661 aagccccgga aattcgaagc gtcacggatc aagatcccgt aattatctaa aaggaattgc
    27721 tttaaatcag cggctgtacc cttcttcaaa cggacaagga agaaagtcgt agaggtcggg
    27781 attacctcca agccatccaa tttacttaat tgataaataa aatccgctgt ctcacgctgc
    27841 catttacgga tcggcaacgt aaattgcgcc ggatggatca agatatattt acttgcctcg
    27901 atagcgatag catttaccga ccaaggtatg atatacttgt tcactttctc cgcaatctcc
    27961 ggagaagcga ccagataacc gatacgcaag ccggggatat tataggcctt cgagatagac
    28021 tggacaagga ttaagttctt atgcgttttc acgtcactcg gctttagcat gtcttccgtc
    28081 gtaaaagcca cgtatgcctg gtcaataatg aaggtagtct gcggattcgc cgagatcaaa
    28141 cggagaagct ccgtacggtg gatcagcttt ccatccggat tattcggatt acaaatccaa
    28201 cagaaatcct gtccctccaa ggataactct gataaatcgt ccgatgtcgg gaagaaagag
    28261 atctcatgct catgcaaacg gcaagcgtcc tcatattcag agaaagaagg aatagcgatc
    28321 atggatttcg cacctcgcca agcttgcgct aacaaataaa aagccgtgat cgagccattc
    28381 gtcactacaa tattctcttc cttgatctca taccggcggg ccaacaatct tttcaaagta
    28441 gcggcgtccg gctccggata acgagtcagc ttatcaaaat gctcgatcaa atgttccttc
    28501 agtttatcta aattagctcc gtgccacaca ttcgagctaa agtttatctt tacctcgttc
    28561 tttgcgttat aaaaatcatc accgtgtccg tataacatat acctgctttt taattaatac
    28621 ctatctgtta aaactgtcac aaaattacga atctttttgg cttttcctat caatcgcctt
    28681 atagatcgca tcctgtatgc gagtacgtat atcaagcgat cccagtttat tatttgcccg
    28741 gctaggattc acccggttac tcaaaaatat ataaataagc tggttatccg gatctaccca
    28801 aaaacaagta cccgtaaatc ctgtatgtcc atagaccgag gcgggagcca aagccccaca
    28861 aggcgaggct ttcggattac caatcaccgg cttatcaaag cctaaccctc tacggcaagt
    28921 cgggctcttg ctttgtgtaa acaaacggct ggtttccaaa gaaagatagc gctcgccgcc
    28981 ataagtccct tggtttagca tcaattggag caccttcgcc aaatcattcg cattcgaaaa
    29041 taatccggcg tttccagaaa cacccccttg aaaagcggct gcctcatcat gtacatatcc
    29101 gcgaagcaat tggcggcgga caaatccatc ttgttccgta ggtacaattt gcaaggtatc
    29161 cattcgcttc aacggattat aagtggtatg ccaagcccct aacccgctgt agaaatcatc
    29221 ccgaagaagc tggtccatcg gagatttcat cagattttcc accatcattt tcagcataat
    29281 gaaattcacg caactatata cgtacctacc tctcgtaccc aaacgggatt tcttgatatc
    29341 ttgaaggacc gtatctttaa aggaatcact cacatagaaa ttacgggcta cctcagtcgt
    29401 aaatccgggt ttccgtgtat ctgatactat atccggaaga tatttaaaat cattccggac
    29461 atacgtttta gcgtcaaaac gaaccgggtg cgtggcgttc ttcgccgaac tatataaact
    29521 gcctttataa ctatccttat caatagcatc cagatagaaa ttaatagttg gagtcactcc
    29581 cgattgatga tatagtaact cttttatcga taaatccttt ttattagact ctttcaactc
    29641 cggtataaaa tcggagatct tattgttcaa ggtgaatttc ttctcatcat acgctttcat
    29701 gactgccaat aaagtccccg ccgccttcga tgccgaagcc aagtcataaa ctgacgcctc
    29761 cgtgaccggc tgcctacttt cgtaatcaaa ataaccaaac gatttattat agataatcat
    29821 gccgtccttc gcaaccaaca cttggcatcc gggataagcc ttctcatcca atccctcttt
    29881 aacgatcgac tcaattacat ccaaacggtc cgggttcgct cctacctctt ccggctggtg
    29941 ataccccaaa cgagtcttct ccgtaaaaac accggtaccc gcataataca atcccggaat
    30001 cgaaaccgga agtttccctt tcgccgcaat accaccgaat atcacttggg ccgcatattc
    30061 ctgcgctaag ggagtgccct cgtaagccaa cacgaccgcc ttcgccttct cgatcgactt
    30121 cttatattcc ttacaagcat atggcaaggt aaagaaagca tagaccaact ctttcttcgc
    30181 ggccaactgc ctcaacgcta aactctcggg aatgcgaatc gtatgtacgc cacaaatgat
    30241 cacgtcgtat ttttgcaatt tattataaac ctgctggact tgggcagccg tagaacgccg
    30301 tccgatgcta aagcaagcga tcgaatcata ttcgcccagc attttctgga attcattacc
    30361 aaccccgtct ccaatcgaga gtgctgcgat ctttttctta ttcaactgtt taagaggtaa
    30421 gatcgtatcc tcattcttca aaacggtaat agcctccgaa ttcaacttcg ccgccatcca
    30481 tgccgcatgc ggagagttca aacgtttcga taagcctttt gtttcgaccg gcttataggc
    30541 attcaatcca gcgatatatt tgtaccttaa tattttcaag cacttggcct cgatcgcttc
    30601 cagatccaat accccttcct cgatagcctc tttcacggcc gtaaaatcat tgattggagc
    30661 ggccggagcg agcaagatat cattccccgc aagcaaagcc ttcaccgaag gattatctgt
    30721 tttctttgtg gaagcccctt tcatcgctaa agcatccgta aagcacagac cttgaaaacc
    30781 gagttctttc tgtaatagat ccgtcactac cgccttagaa aaagaagccg gcttatgact
    30841 tttgtccaat gccggaacat aaagatgtcc cgtcattatc ccggcgaacc catcatatat
    30901 ataacgttta aaaggaagaa gttccacgct atccaagcgg gcccggttat ggcgcacaac
    30961 gggtaatgtc tcgtgcgagt cctcggaagt atctccatgt ccggggaaat gtttggagac
    31021 agacaagatg cccgtacttt ccaatcctct tgcgtaagca atacccttct ccgccacagc
    31081 ctccggattc tcgccaaacg aacgcaggcc gatcacggga ttatccacat tgctattcac
    31141 gtccatatcc ggagcgaaat ttatatgaat tcccatttcc cggcactgcc gtcccacctc
    31201 ttttccatat tcctcgatca aggcattgtc ctcgatagcg cctagcatca tgtttttcgg
    31261 gaaacgggtg gttccactta atcgcatgga aagtccccac tccccatcca aagagaccaa
    31321 catcggaatc cgggaagcct tttgcaaacg attggtcacc tccgcctgcg tcaccggatc
    31381 ccctttatgg aataagatgc ccccgatctt gatatcgttc acgtaacgca tgagccgttg
    31441 catattccgg ttatcggatt taggattcgc tataaccata aataactgcc cgatccgttc
    31501 atcataactc atagcgtcaa acacggaatc aacccaatga ttcatctttt cctgatccac
    31561 cgcacgataa aggttcggga ctgtttgcgc cccactcgat aaaagggaaa tacaacacaa
    31621 aagcaagata ccaatctgtc tcatcacaac attatcatta ttactctcca aaaataagaa
    31681 aatatcgcaa tagtaacgtg aattgtgata ggggttttta ctatctttcc tgtctcgtaa
    31741 taaaaaagga agtacttcat gaagctaata ctactcataa tcttgattat cttcggcttt
    31801 caatcaagcg cttggggaca ggcgccgact ctcagtatcg aggctaaaca agagccgatc
    31861 caagaaatca tgaaaaaaat agagcatcaa acaggcatga cattctccta cgatccttct
    31921 attctcaaag gcatttcccg gattacattc aaatctgata accaatccat atcggaatgc
    31981 cttacccggc tattccaaaa gctccctctg tcttatcaga taaacggtac ccacatcatc
    32041 ttgaagaaac gcccccgctc agtaaccatc agcggattcg tacgggataa agcgactaca
    32101 gaatatctaa tcggggcctc cgtttatgac tctcgcacac aaaggggcac agctaccaat
    32161 aaccacggtt tcttcagtct aaccttaccg gtcggggtag tccgtctgga gacttcctac
    32221 atcggatacg gacgtttctc acatacattc caaccgctcg aacgggatac cgtgatggaa
    32281 attctgctgg aaagcggtga ggcattggcc gaagttgtcg ttaccggtag taatgacaca
    32341 caaaacccga tacaagcccc tcagatggga acgattaaaa taacccggaa gatgatcaag
    32401 accatcccga ccttattcgg tgaggctgat gtgatcaaag ccctgcaaac ccaacccggc
    32461 gtatcagccg gaacggaagg attagccggg atgtatgtcc gtggggggaa tggagacgag
    32521 aacctgtata tgatagacgg aatccaactg tatcaggtca atcatctcgg aggacttttc
    32581 tccgctttca acgccgaggc tttgaaagat gtggattttt ataaatccgc tttccccgcc
    32641 cgctatgggg gaaggctttc cagcgtagtg gatgtgcata ctaaagatgg caatatgaaa
    32701 gagtaccatg gtagcgctat gctaggattg acctccggta acttaaattt cgaagggccg
    32761 atcattaaag accggacttc gttcaacgcc tccttccgtc gctcttggct ggatgcctta
    32821 tccgcaccgg gtttggcgat ctacaataaa attcagaaaa agaaggggga gaaattcagc
    32881 gcacgctatg cttttaccga tctaaaccta aaagtgaacc accatatcaa tgaccggagc
    32941 caagcttacg ttaatttcta tttcggacag gatttcctaa aaggaggaag ttctgagttc
    33001 tccgtaggtg ataatataac ccctttcgag aacaaggact ttggaaagat gcgctggggt
    33061 aacatcgcat tgtcttccgg ctggtcgtat gtgtttaaca acaagatgtt cggtaccgtc
    33121 accttggctt attcccatta tcaatccaaa ctaaaacaag agacttcaca atactacgga
    33181 accgagggtg acaaagatta ttcttcacgg tttatcgaga cctcaacccg aaacggtatc
    33241 aatgatttcg gagtccatgc gaacttcgac tatattccta ccttggcaca tcatatccgt
    33301 tatggtaccg actatcttta ccatcgtttc agtccggaat atatcgagga aaagacctcc
    33361 gagaatttgt ctccgaccaa acgaactacc ggagacgagc gcctttcagc gaatgagttg
    33421 gctgttttcg ccgaagatga ctgggcgata tctcccattg tccgggctaa cgccggatta
    33481 cgcctgaaca tgtacaatat acaaaagaag acatatgtct ccttagaccc tcgtttatcc
    33541 gtacgcttcc tgctcacgag ggatctaagc cttaaggcct catacgcccg gatgaatcaa
    33601 tacgtacatc agattagcga aagttatatg agtctcccta ccgatatgtg gatgccggtc
    33661 agcaagaaat taaaaccatt ggtgagtgat caagtatccg ttggcgctta ttacaatctg
    33721 cacaagaact attccttctc ggtggaaggt tattacaaat ggatgaatca cttactggat
    33781 tataaagatg gttacaactt cttaccctcg ttcgtcggtt gggaggagaa gttggccgcc
    33841 ggtaaggggt gggcctatgg agcggagttt atcgcccgga aagagacggg gcgtataaca
    33901 ggatggatcg gatacggact aatgtggagc gaccggcagt tcgacgagat taataatggc
    33961 aaacgtttcc ccgcgaaata cgataaccgc cataagctga atatcgtcgc aaactggaag
    34021 atcaacgaga aattggaact gaccggaagc tggactttca tgaccggaaa ccgggttacg
    34081 gtggcattcg agaattacga ggatttgggc ctcactcctg tccctccgct cttaccggaa
    34141 ggaggcttgg actatttcac ggagcgtaat aacgtacgtc tccccgctta ccaccgctta
    34201 gatctgggga ttaatattta tcgacctaaa aagaacggcc atctcggtat ctggaatatc
    34261 agcgtatata acgcttattg ccagatgaac ccgataacta tccataagcg gtcttggata
    34321 aactatagcc attatttcga gacgttatcg ctcttaccga tcattccgtc tatatcatat
    34381 acttataaat tctaaagaac atgaaaccta tattctattt atcaatctta ttatccagca
    34441 tgctcctaac ctcctgttac aggaagtttg acctagagga atatcgtact acaccaaaaa
    34501 tggtgatcaa ctcggccttc tcgccagata cagtcgtaat ggccagcata tcccgcacat
    34561 ggtttcactc agagagcaag ccggacgtaa cgattcgaaa cgccaaggtg gaattataca
    34621 tagacgggat cttcaaggag gagatgcctt ggaaagaata ttcctattgg aaatcttctc
    34681 gttggctcgg agaggatcga ggtggatggg taacagatac gctttatata tcgaatacgg
    34741 ttccacagcc cggacaaacc gtaaagatag tagcttctac cccggaatat ggaacagcct
    34801 cggcggaaga taagattcct tccaagaccg aaatcaaagg cctgcgcata attccccgta
    34861 aagaagctac cggcaacggc ggtacccttg tcgatggaga tgggaatatc tcctacatag
    34921 aagaaaacga tgtacttatc tatcaaatca ctttccaaga taccccgggt aaatcaaatt
    34981 actattctct acagatatgg ggagatgacg accatcttgg tgtcctgttg gacttctccg
    35041 tagatcccgt attcacgcaa caacaaggta tcttggatga ggttttcggc tcttcgatgg
    35101 taaattggcg gggacgggta ttttccgacg agctgttcga cgggaaggaa tacacgttgc
    35161 aagtaaaaga acaacttagg tccgatacta aatattatac caaacgccat attcgtttat
    35221 attccctgtc cgaaccctat taccaatatc tgctatcttt acaaaacatc gagaatgaag
    35281 gtatcatggg cggacttacg aatgtaggtc tggccgagcc tgtccggatc tacagcaatg
    35341 tggaaggagg aacgggaatc gctggtggat gtcaatggtt tgaatccttg gtagacataa
    35401 aagatttgat caaatagcga gcaaaaaagc atctatctat tgcgaatcaa atatttattt
    35461 cgttactttg cacccgcttt acgtaatctc tgtcgggaaa tgtagcccgt taaattgcgt
    35521 ttcattataa attacaatta aaaagctata aacaatggat ttaattaaga ttgcagaaga
    35581 agcgttcgct acgaagaagg aacttccttc attcaagagt ggtgatacga tcacggtagc
    35641 ttaccgtatc aaagagggta acaaagagcg tatccagcag tatcgcggtg ttgttatccg
    35701 tatctccggt cacggcgaca aaaaacgttt cacagttcgt aagatgtctg agaacgtagg
    35761 tgtagagaga attttcccga tcgaatctcc gtttatcgaa agcatcacgg ttaacaaagt
    35821 cggtaaagta cgtcgtgcta aattgtacta cttgcgtgcc cttaccggta agaaagcaag
    35881 aatcaaagaa aagagagtct aatctctccg attctattgc catacgaaaa gccatccagc
    35941 ggaatgccgg atggcttttt gtttatcgtt tcttacaatg cctatcgtaa gcatctaaca
    36001 atgcccattc aaaggagctt acgatgggca ttataagaac cttagaatgg gcattgaaag
    36061 aaatcatata tccaagtcgc ccacgattca tgaatgaata tcgctgacag ataatttgga
    36121 tatgctctaa aacaagggtt catcaaaagt cattttcacg agataccact cccttcccta
    36181 taagagatat acttcaagtt ccacaggaga tatacttcat cggtaaagta agtactacct
    36241 ctacggaatt cccatttata gataatttca tccacggatt ttatcgcatg agccgctttt
    36301 tacgtacatt tgaagcaaat ccacctaagc gacatggaaa aatggataaa caaatcgaac
    36361 tatcgcaaac agaaatagag ctagcgttcg cttccttttg tatagaagga accgcacgca
    36421 aattggggca gccttaccaa gaggtgttcg cacgcatgaa acgggtagga atgatagaga
    36481 actatatcct acccaattat aatatattgc atactgaaag ccgcgaacac gtaatcgaca
    36541 atatagatgt aacttacttc cgactattca atatacccga ttcattatct gaattataca
    36601 acttacgatc cacggatttg tatttgcgac cgaaatctaa gtggtaagag aatccaatct
    36661 cgaagcccgg ataaatatca ccaaaacgct gatcggtcac atagggagcg atcgctgaaa
    36721 ggttcttact ccggtaacgg gcggatgatg taaattgggt agagaaagaa gcgcttaact
    36781 gaaccttccc gatcctataa ccgataccca acctattaaa acgatcggcc tcacgactgg
    36841 tctcacccga aaaactatag cttctcttat aaatcaacag gttaaaatta aagttcttca
    36901 catcgctatt caaagagatc acatagaagg gatccgtgta tgtatgcgaa tagctatttc
    36961 cattcgattg gaaatggttc aagcctccgg agatattcat gcgcagataa tcgccgaagg
    37021 gtgaataatt caaatacagt tccggcgtaa aacgatggaa actccgttgg ttatcgtagg
    37081 tgcggataaa aagtccccgg ctagcgtcat acagggtctc ttccatgacc atgcggggct
    37141 ggtattggta agagaaagta aagccggcct tgacctttgc cgtattcaca tgaaattcca
    37201 cggcgttgtt atgatataag aaaggggata gacccggatt acctctacga acctgtaagg
    37261 aatcaatcca ttgctccacg ttactcaact cagacaagga tgggtttaca ttgcgcaggg
    37321 tataccggta acgggcggat aatacctcat tgatagtata agtaagcgtc acctgcgggc
    37381 ggaagtacca ccgattgtag gagtccacat tttcttgcga tagataatta cgggaggcac
    37441 ccaaacccac attataaacc aacttcttcc aagttcctac gtattgcgca tacatatacg
    37501 actcggactc tgtcatatgg gtcgtataat caccggagcc ggaatacacg ttatccgtat
    37561 aggcttgcgt atgtttcaaa ccagcggaaa ttcggccggt ctccagctct ttctcgtaga
    37621 taccctctcc gattaccgaa tagcgctttc catctacttt cgtataaata tctgtcaaag
    37681 gaatactttc cagttcttcc cggtaggtat gacggctatc ggtattcgaa taagttccca
    37741 cgacattgac agccaatgat tgtttacgtg gtaatttccg gaaataatac aagtcgagcg
    37801 agggacgggt attcaaggat ttattattat cgataagatg ggtcgtagcc atactctcgc
    37861 tatttcttaa aagggcgtcg ctatagttat gcggatagtc gtaataatac aagttcaact
    37921 tagcgttcaa gaaataatca tcatccttcg tgtagttata attcgccgtc gtagtccaat
    37981 acatctcata atccctcccg gggattcctt cctgtgttcg ctggaaggta ccgtctgggg
    38041 tatgaaagat ttccgtccgg tcttgccatg cctctttata ccggtgtccg ttcgcaaagc
    38101 tggataaaga aaattccgaa cgtccccggt tatacttacc atatatataa tctgccatcc
    38161 aaaacgtgtt taattgatgg cttaaatcca cgccgagatt tcctccggaa gtccgcttga
    38221 tcgttatata atccaagacg atatcgattc cttccccata tcgcaagccg gggttatcgt
    38281 gatattccac ccgtttgata tcctccggcg agagggcggc gacttctaag gaagaagcca
    38341 acacgccatt tatacgcaac tgaacgtttc cattcgccat agagatactt ttcgtattcg
    38401 gatctaccca taggcgaggt aaagacatcc gccttgtcaa atccaagcca tccatcgagc
    38461 gccgcacttg gtctttggag gggaatataa gttgacggtc tttcttcctt ataatcgaag
    38521 aggcttgaat ggtaacctca tccaaatcga tcgttttctc ctcttgcgca tttaccaaaa
    38581 aggcaacgca aatcaatccc acaaataata cttgtcttct cataaaattc aaatttgatt
    38641 cgagacaaat gtaaggaggg aaacagctaa aatcgattta tacaggcaag aaactaaagt
    38701 gcaaggcatt acgttcatat actgatttac aaagtattag cgaacgactt agagagaaaa
    38761 gtttatattt gccgtttgag cacttatatt gccgatgata tcctctttct catccatacc
    38821 cagcttatgg cggatgtccg tcttgcgctg atagatcgta cggacgcttt gttgggtgac
    38881 tacactgatt tccttggtag agaagccggc gcatagcaag caacaaagct ggatctcttt
    38941 ttccagcaaa cgcccgtcag acaatcggac cagatgcgta tggaaattat catagaccgc
    39001 atcgataatc ggatacaggt catcccatac caaaagcgta tctaccggga catcctcatt
    39061 cgtgatacga gtcatttgct ggagcaattc cttattttgt tgcgtgggag tagtcgccat
    39121 caagcggata acacccaatt gctgcaacaa gaccttacgg aaaaaggcac tatcgggttt
    39181 ctcctcctcc gctacggatt gcttggactc gttcaagagc tgacgcaagg cttccaaacg
    39241 ctcctccata tcaatcaaac ggttccttcg gttacggata tataaggaaa ctccaccagc
    39301 taccaatatg gaaagcaagg aaacgatcac taagatagag aacgtacgct gccggctcat
    39361 ttccaagcga agattttctc ggcgtaaacg attttgatcg actaatcgtt cccgctcagc
    39421 cttctccgtt tgggatttca cggtatacaa agaatcgcaa tattgcccta atcgggaaat
    39481 atcgaccggt ttattttcct ttacgcccaa tataaattga taggcataat taagcgcatg
    39541 cgaggctata tcatcgctgt gactacgctc caagtctaac gtattcttct cgatatactt
    39601 ccgggcagaa tccagctccc ctagattgat ccaaggcata acataggatc ccaagatttc
    39661 tcgttccgga taacgttcct tcagcaaacg cagatatctg atagaagcct tgggattaaa
    39721 gtcatacaag aaatccgcat aattacgggc aaaatgatgg gcataccatt cgatattctt
    39781 agccaaggcc gagtccgcag ccaaacgaag ataataatcc gccgagtccc tcattcgcaa
    39841 gcggctataa ctcaacccgg ccatataata ggccatctcc ttaaatccag cttttggcga
    39901 ggcttcccat tccttcgact ctgcgattgt ttcccgatac aacccctcac caaaactcaa
    39961 ggaagtcaat cggtcataaa aacgtacaag gtaggtcgaa tccgaacggg aataagcgga
    40021 atctatcgcc tctcggtaca aggcacgcct ttgttcaaac cccttccggg aatcccccat
    40081 ataaatagcc tttacgaaat aagcggaaag taaaggctcc gaggcatgct ccttataata
    40141 atccacggag tagtcgatga gcgagtcgtt caccaagctg cggtcctgca agagatgaag
    40201 ccaagcaagc ctccgtccat actctgcctt atcgctatcc gaaagagcgg aaagcgttat
    40261 ttgctcctcc agcagccaaa cggcgctatc taagttattc tcgtttacca accggtccgc
    40321 ctccgcgaat ttctcccgta cggatttatc gccacaggaa agcaacaggc agacattggc
    40381 cagcaatatg tagacaaacc atttcgtcat agcgacagag atcctaattt ccggcaaagg
    40441 tacattattt tcggaagccc gggcgattca ccgatatttt tatccgtttc gtcgattcct
    40501 tttcccgctc ggataaggaa gtcctatctt tgtaagcaga caaagggttt atctatgtta
    40561 caattaaaaa gaaacgactt attgatcggc ttcacgatat ccgtcttgct tagtattttc
    40621 gtgaacttcg cccttctgat gcgtaaatat gagttcgaga cagggaaccc gggcatgggt
    40681 atccagcctc cggatcgcac catgtattat ttgctaatct ggttcttcgt gttctccttc
    40741 atcttattta ttgtcaacag cttgatgtat aagttcggag acaagctttt ccgcaggaaa
    40801 gagtataaaa gggtattggt ggtttgcgta acttgtatca gcatcgccta cggcatgttt
    40861 catctgtcgc cggttttgta cacggccatt gttgtagaat ggctgggaga agacggacct
    40921 cagccagcta cccgggatat catgatccgc atcaaccggg acaggatggc tacgcaaacc
    40981 atcaggcctg ccgagcatcg ggacataccg gtaccgccca atcctttcac ggtccctaac
    41041 tctttcatga cggagcatct tttcgtcttc ctcacggtca tgctaagctc catactgatc
    41101 cggctgctgg gcagcaagca gcaaatgaaa ctggaatatg agcaattgaa gaccgagaag
    41161 ctacagaatt cctataacgc cttgatggga caaatcaacc cgcatttctt cttcaactcc
    41221 ttaaatggat tgaacgcctt gatacagagc ggagagaaac aacagacgct ggcttatctg
    41281 gatgagctat ccaacgtctt ccggtatatc ttgcaaagca acaagaaaga gctggttacg
    41341 ctagcggaag aacttcaatt cgtaaaggcg tacacttatc tgctaagcgt gcgctacgag
    41401 ggaaagctat tcttctccat ccaagcggat accccttact tgctttggta tctgccgata
    41461 ttgagcgtac tccccctgat cgagaacgcc gtaaagcaca acgttatcag caagcaatac
    41521 ccactacaga tcgatatcta taccaccaat gaggacaaac taatcatatc caataaaata
    41581 catcctaagt cggaagatag caaaggtagc ggtatcggat tgaagaacct atgggggcgc
    41641 taccggatgc ttaccggaaa ggacatccag atctccaacc gcaaggaata tttcaaggtc
    41701 acgcttcctt tacttaataa acccattcac tcatgaaagc agttattata gaagatgaga
    41761 ctaccgccgt taatagccta aaggcgatct tggcgcaaaa tacggttact cagatcgaag
    41821 tgatcgccga gttggagagt atcgaggaga gcgtggattt cttccggaca tcgcctcatc
    41881 cggatatcat cttcatggat atccatttag cggacggatc ggcgttcaag atattcgagc
    41941 aggtggagat agatgcccca gtagtcttca cgaccgccta cgatgagtat gcgttacagg
    42001 cttttcaagt aagcagtatc gattatctac tgaagcctgt cacgctggcc tcgctggaaa
    42061 gggccttgaa taaattacgg ctgttcgata ccgaggaaag gctggcgcat atccggcaaa
    42121 cgaaccgtac gatccagagt cgccacacga tcaagagcct gttgatcatg ctggccgata
    42181 aattctatcc gttggcggtt gaggagatcc tttatttcta tacggccaac gagaaggtta
    42241 ccgcctatac ctccgacggg aagcaacatc ccgtagaccg taccctcgac gcgttgggag
    42301 agcaactgga cgagaggctt ttcttccggg ccaaccgtca attcatcatt tcacgcaacg
    42361 ccatcaagga tatagatctt tggttcggga gccgcctgtc cgtcaacctc accttgccgg
    42421 ttcccgaacg tatcatcatc agcaagacca agaccccgat cttcaagaaa tggattctga
    42481 gggaagagga ataatgtctt ttcaccccct cccgtaaggc gattcaccga cccgattata
    42541 ccactaatcg gcgcttaacc tttctttacc gaactttcct gttatttcgc ggtacaacaa
    42601 ataaaggtaa aaacactatg ctgaaatgta tcactttcga cggagacgcc tcgaccctga
    42661 acacgctcat gggatatctc gagaaactgg acaaggcttt ggccgatgtc caccaagtgc
    42721 tgagcaagga gcaaacagaa cgccccatct tcgtccggga gggcagcaag atcattcgcc
    42781 ttcgccggga agagatcctt ttcctcgagg gatacggcga ttatgtaaag gtacaccgta
    42841 tcaatggcaa gcccctgctc acgcaagtca gcttgaagcg gttcgaggag tttctggaca
    42901 ggaatcgttt ttgccgggta catcgttctt acatcgtatc cctctcccac attaattata
    42961 tcgagcgcaa gcggatacgt atcggggagg aactgatccc tatcagcgat tcgtacctgc
    43021 ccgccttgat gaataatctg gctctccaag agtaaccaag agtttcatgc ggaagaaact
    43081 tttgtttctc cgtgacaaaa cttttgtttc ctagtgaaga aactttagtt tcataggcag
    43141 aaaactaaag cttcacttgg tagaacttct cgcttaatgt ataggtcacc gtaaagccca
    43201 tgatatctct tcgcaacgca ttcccttgca attggagacg atcgtaataa aacgccgtat
    43261 tgatacggcc attcaggacg ggtaatccca agccaacgct tacccgatac gccccgccgg
    43321 attgtccttt caaccgcagg taaggcgtgg aaacagaaac acccgcttta taagacatcc
    43381 gtttccaata actgctggag ctaaatccat tcgggaaata gcatacgccc aagcgtagct
    43441 catgcgaatc ccggaacttt acccggctat cgctcgagtt caataccccg tattgccgga
    43501 atagatagtc caacgcatac gtccattttt tatgcgccaa tgagctaccg atgcctatat
    43561 attgaggtag atattgtgtc acccttttct ggttataggg ggtttccgtg ctgcttcccg
    43621 tcaccgtcac cgtatttttc aatgagatcc gttgcttata accgtaaatg gcgccgaccg
    43681 ttagaaaggt ttcccgggcg atcggacgat gatattgtaa accgaaatcg gcgtaaaaag
    43741 agcggccgga catctccctt gacactgtca tcgcactttg tatctcattc tgtgtcatat
    43801 ttccgaagat aaaattaaga ttcataccga ctgatagatg cttggtcaat gaaaaacctt
    43861 gggagaggaa agccttggaa agtccgcctg tccccgaaaa cgtactggtt acaaaggtgc
    43921 cgggagatcc ttccaactct tgcgaggact taaaataata cccaacaaaa ctataaggag
    43981 ttaccccgac ggacatatac caccgtcgca tgatacgccc tcccaatgag aaagcggaga
    44041 aattcccggt gaatgcgctg ctagagctcc cgtctgagcg gtatcgttca ttcttcacga
    44101 aggcagatgc ctcagcgaac aacttacaac tatccaacgc tgtcaatccg gcaggattct
    44161 ctatattcat cagcatccct tcccgcatgc cgacagtgac acccgccatc gaggtatttt
    44221 gaccatataa accggaagcc atctcaccca gtccaaacat cgagtaaggc gaggaagtca
    44281 tcgtattctg cgcggatgcg cttgccgcca tcaagaggca agggtaaaga aggtatctag
    44341 taactttcat agaccttata aatgagttgt agggtgaccg ggttacgtcc tccctgatcg
    44401 ttaaacgtca agttcttgaa cgtgccggtg taatcatcac tattaaaaac caactgaaga
    44461 ttatgcttat acatgccaaa ggcacctagc tcctcttgca tgaattgagt cacgtcgaaa
    44521 taataatagg tgttctcgtt aaacgtattg tcttccgata gcgtacctcg ttgaacctcg
    44581 gaaccgagat aatcggtcac ggcatccgtc accacattat tctcatcggc gatatatagg
    44641 tagaggctgt ccggcaaggt attgtaatcc gaataagtgc cttgctcggg ataaatctta
    44701 agtaaagcgc tctcaatctc cacttgcgtg ccttgttgca tcagattatt caaatacggg
    44761 aattccagac gggtatacca acccaagcct ccgaataata caccccggtt accaagctcg
    44821 gccgaaggta tctccactcc tttcatcgga tatcctgcca tatccgttcc actacggtca
    44881 tggtcaatat gattgaactg ggtatccgta ttcgggaaga accataattc cttctctgtg
    44941 gaaagctcat cggacaaatg ataatgcagg actaaagcgg cggaggaatc ggctaccgtg
    45001 aaagtcagca gagactcgct tcccgccaag tccggcacga tcgccacccc tttgaaataa
    45061 tcctcaaagc gctcctcgga caccgcttga tcctgcgcat gaaaacggga caagaggtct
    45121 tgccctagcg catcgggaag acggacttcc agtttctccc cccccttcgg cttcggttta
    45181 aatgagcaga ccgccaaagc ctcgggagca taagagacac tgctattatt atataacata
    45241 tggttatata cagcaggata ttgttcttta aacgcttttt ctgccttttc agaagcacca
    45301 gttatagatt catcaaattg gtatgggaaa tgcca
//
LOCUS       DBMDTB010000021        45259 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_331_length_45259_cov_10.364188, whole genome shotgun sequence.
ACCESSION   DBMDTB010000021 DBMDTB010000000
VERSION     DBMDTB010000021.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 45259)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 45259)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45259
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_331_length_45259_cov_10.364188"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..3059
                     /locus_tag="ACZPB4_05420"
     CDS             <1..3059
                     /locus_tag="ACZPB4_05420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="SusC/RagA family TonB-linked outer membrane
                     protein"
                     /protein_id="HIR1097695.1"
                     /translation="GASVIVKGTTTGTVTDFDGVFSLDVPSSAKTLVISYVGMIAREV
                     PVQDVLRVVLQSGTQNLEEVVVTAIGMKKQEKALGYAASTVKSEDLNAAKSGSVMSGL
                     TGKVAGLNITSGGATGSSQKVIVRGISSFSANQPLYVVDGVPIMNDFQGEDSFSNSVD
                     FGNQANDINPEDVESVTVLKGASATALYGSRAANGVIMVTTKRAGAERLSVTYDGSFM
                     GSSVLRVPQTQDRFGQGWGSFGPMENGSWGPVLDGRDHIWGPYSDGSEGLLTPLSKPF
                     SYVKNNLRDFYETGFETNNNVSIRMGNDKLGFVASYGNVKSDGVLPGDADSYARNTIS
                     LRGNMKYKRFSAELNLNYVRKDITQAAAGQGDDGATMFSEILQHAVDVDISSMKDYTN
                     PYFNTDNFYTAYAENPYWVLDHNRNKYQDDRVYGKIELAFEIMKGLKAVGRLGGDFTN
                     ATQKRWNEKVTFASGSWSELGGKKQQPGTYTERRDKVEQIDATAFLNADYKIGEDIAL
                     NGMIGWNLNQQTSSYLKSYLYGLEQPGWFNLANGVDKPMTTTYSDRRRLVGLFAQGEF
                     GYKNFWFVNASIRNDWSSTLPQGNNSFFYGGVNTSLIITDMFEDLKSDYLNFLKVRAA
                     WGQTGNDAPIYRTSSYFTPTQISLGFGDLYLPINNTLGLTEYNRLPSMDLRPEITTEW
                     EFGLTTHLFNNRLDIDAAYYNKSTKDQIISASLAPESRYTSMTRNVGKIANQGVELAV
                     NGIPVRTKDFEWGLGFTFSKNWSEVKELWDDVTEYKLTSSYQVDFVAEVGQPLGVFKV
                     PALATTDDGKVIVDNNGMPTIDASKKEIVGTSTPNFLMGFNTHFTWKGITLSAVLDWR
                     NGGEFYSYTSQLLTFAGNSTYTVFNNREPFVVPNSVKVVNGQYVENDIPIVHWGGASS
                     AVNTYYNNASNYAQYRNWILPKDYLKLREITLSYSLPKAWLKQTPFSMVQVSLIGRNL
                     FMWTPKKNNYVDPEGTNYGNDILSEIGEFGAAPTNRTFGGGIKVVL"
     gene            3087..4559
                     /locus_tag="ACZPB4_05425"
     CDS             3087..4559
                     /locus_tag="ACZPB4_05425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SusD/RagB family nutrient-binding outer membrane
                     lipoprotein"
                     /protein_id="HIR1097696.1"
                     /translation="MKRNNLIYTGLVSCLLMATTACSDYLDINQNPEYPTEASSSTLL
                     PSGIAGVASIVGGTYELYGSMWSQQCTQGHTSNQYNTLVNYTITNASDSRLWSIPYSI
                     ALPDLDLVIKSSESAQEWNYWVMGKTMTAFMYHILVDSYGSIPFTEAILGNENTTPKY
                     DDSKTVVYPGLLAMLDEIIAKKAEATAGGLPSVTKQDLVFAGDVNKWIQFAKSLKLKL
                     LMRDFDTNKAAIKALLDEGDLLSVDAKMDCFQDLENKSNPLYENDRRKLNSTVNIRAC
                     ATVCDYLKKYEDPRLNDFYSPNTDGSGETTALKYGDRPNSVAVTTRMISVAKLGPTDP
                     VYFMSAAEVAFLQAEAYARLNDVAKAKVAYEQGVNYAFERWGYSAAEFVSEGAPYAFD
                     STDQNSMLTSILTQKWIASTRCQAWDAWFDINRTGIPVLGTKHVDEEGYIWGQLTPCI
                     GSALAPGEYPRRLLYPKSSSDYNPNTPAVVPLAEKQWWHK"
     gene            4603..5103
                     /locus_tag="ACZPB4_05430"
     CDS             4603..5103
                     /locus_tag="ACZPB4_05430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid-binding protein"
                     /protein_id="HIR1097697.1"
                     /translation="MKQINKLLVILLALVTFSSCETYGDYEIEYTAIYPLCGEWVVNV
                     TGEDGGVLAEGVTCNTYNTTDDATDKMWIKMSVATNDWGVRGKIHCDVTSKSFDGDGI
                     ANLLHADDGINSTVTFNISGKVIVDGYTTQANTKVDAIEFTLTQNGKSMTVKGFRKTG
                     WEGEDY"
     gene            5292..6470
                     /locus_tag="ACZPB4_05435"
     CDS             5292..6470
                     /locus_tag="ACZPB4_05435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HIR1097698.1"
                     /translation="MEKVIYNLVFNRKKQLNAEGKALIQVEAYLNRQKRYFSTKVYVK
                     PCQWDNKRRSIKNHPNMDALNLYLQNYVMELERDELEKRQANNGFSLKDLREEASSTS
                     TSSSFLVFMREEILHSNLKESTLKNHLSTLHVLSLYKKDVLFKDINFNFLCDFEYFLL
                     KQEYHRNTIAKHMKHLKRYINLAINKELFELHKYPFRKYKIKYQESKRTHLTPEELGR
                     LENLKLDGQRTLRRCLDMFLFSCYTGLRFSDIVSITKENFLIIDDKVWLVYSSVKTDV
                     SVRLPLFLLFEGKSLPIYERYKNAPRTLFGVPLSSNSNVNKQLRRISQLASIDKKVSF
                     HTARHTNATLLLYNGANITTVQKLLGHKSVRTTEIYSNIMDMTIVRDLEKIETRLKFG
                     "
     gene            complement(6561..8090)
                     /locus_tag="ACZPB4_05440"
     CDS             complement(6561..8090)
                     /locus_tag="ACZPB4_05440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008771703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SusD/RagB family nutrient-binding outer membrane
                     lipoprotein"
                     /protein_id="HIR1097699.1"
                     /translation="MKLQNISKKLLTGVVFTAALVSCSEDKMDEINKDHNHTTAVPAK
                     MILTDVMTSTAFSVVSGDFNLYGGMYVEHETGSHNQFYYAETRSSCTSASTFNNSWGG
                     TYSTLKDALISVKVAEEEQNFITKGIAELFVAYNLAILTDMYGDTPWKEACDYTVSMT
                     PAIDKQEEIYKDIMAYVDAAIEDLQKSDLTSLSNQDLIYKGDASAWLKTAYGLKARYT
                     MRLMGRSADVKGDMEKVLDYISKSYTSAAEQCSYAMYGVGVNINPFFGVFYSRLGEVA
                     SRSMFDKLNERNDPRIRRCYVEANSQTMIASKDDPLLNLAHNGDLVQSQLEYTVSMFC
                     AAQTAPTHILSYHEVLFLKAEALCRLNRKDEAKAVLKEAVVAGMANMEVNIKSALASD
                     YWGGFLNVTNEVTPEEAASYFDENVVPLFDANPLKETMIQKYISFWNADGESTECYND
                     VRRLKSLGEDIYGLQNPGKFPLRCPYGNDDTTTNPNIQAAYGDGQYVFTENVWWAGGT
                     R"
     gene            complement(8106..11279)
                     /locus_tag="ACZPB4_05445"
     CDS             complement(8106..11279)
                     /locus_tag="ACZPB4_05445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SusC/RagA family TonB-linked outer membrane
                     protein"
                     /protein_id="HIR1097700.1"
                     /translation="MKKKLTSVLLFLALSAGVVSAQTSKVTGKVIGEDGEPVIGASII
                     VKGTTVGTVTDFDGNFELEVPANGKQLVISYIGMKSQEVAATSNVNVKLLADTQNLDE
                     VVVTAMGISKEKKALGYAVQDVKADELTKGANTSLSGALQGKVSGVEISPSSGMPGAS
                     SKITIRGSRSFTGDNTPLYVIDGMPVASTADVDTGSSVSGTDFASRAVDIDPNDIESI
                     NILKGQAASALYGMRATNGVIVITTKSGKGARKGKPQVAFNTSLSFDKVSTMPEYQKV
                     YAQGTNGKYSPYASTSWGPLISELPNDPTYGGNTDNEFTKQYGKHEGMYYVPQRAAAG
                     LDPWAQPQAYDNIKDFFNVGTTWSNSVNVAQAFDKGNYSFSIGNTTQDGIIPNTGMDR
                     YNAKMSAEAQLHKNWSTGFTGTYVNSKISKQSSANNGILATVYGAPSSYDLAGIPSHV
                     EGDPYTQNTFRSTSGFDGAYWAVDNNEFLERSQRFFGNTYLKYSTKFNTDNHKLDVKY
                     QLGVDSYTTNYTDSWGYGHANGYGEIDHYGYSITELNSLLTAAYTWNINEDWLFDALV
                     GNELVENQRKFYESYGANYNFPGWNHIDNATTMVASESLRRKRTVGNFASISLSYANM
                     VYFNATVRNDIVSNMPRNNRSFTYPSVSLGWIFTELEPLKNNVLTYGKLRASYAEVGQ
                     AGDYYDSYYTTPVYGGGFYGSTPIQYPMSGITAFTPYARVYDPNLKPQNTKSYELGVD
                     LTFLNGLFSLNYTFSRQNVKDQIFEVPLAGSTGSAELVTNGGAIHTNAHEITLGINPI
                     NTKNFKWDMAFNFSKIDNYVDELAPGVESIFLGGFVDPQVRANIGDKFPVIYGTTFLR
                     NDNGDIVVDEDGLPQIGSEGVIGKVSPDFLLGFNTNFEIYKFRIGATFDWKCGGQMYS
                     GTLNTLNYYGTSMESVESRTAETFRFSHPAVKQLEDGSYVANDIDIKGEDALSYYDRM
                     TLISEAGIYDSGFLKLRELSVSYPIWDKNGINVNLNVFARNIILWSELKGLDPEASQG
                     NNNMGGGFERFSMPGASSYGFGLNVKF"
     gene            11971..15168
                     /locus_tag="ACZPB4_05450"
     CDS             11971..15168
                     /locus_tag="ACZPB4_05450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SusC/RagA family TonB-linked outer membrane
                     protein"
                     /protein_id="HIR1097701.1"
                     /translation="MKKKLTSVLLFLAMSVGVVSAQTSKVTGKVVGEDGEPVIGASII
                     VKGTTVGTVTDFDGNFTLDVPSDGKQLVISYIGMKSKEVVVSPNVNVTLMSDTQNLDE
                     VVVTAMGISKEKKALGYAVQDVKSDELTQGANTSLSGALQGKVSGIDIASSSGMPGAS
                     SKIMIRGARSFTGDNSPLYVIDGMPIASTADVNTDTMNNGSVSGADYANRAVDLDPND
                     IESINILKGQAASALYGMRASNGVIVITTKSGKGARKGKPQISFNTNLAFDKVSTLPE
                     LQTEYGQGNEGAYNPYSGFSWGPSISDLANDPVYGGNVQNEYTEGGLHNGQYYVPQRA
                     AAGLDPWATPQAYNNAKDFFQTGVTWSNSVNVAQSFDKGNYSFSLGNTTSDGIVRSTG
                     MDRYNVKLSGEAQLHDNWTTGFNGNFVTSKIKKQGTANDGVTATVYTAPISYTMAGIP
                     SHIEGDPYTQNTFRENWIDDGNWACDNNSFTERSQRFFGNAFLKYSTKFGTDNHKLDV
                     KYQIGDDAYTTNYSDIYGYGTTGYANGYASEYGFTVNEMNSLLTFTYNWNINEDFVFD
                     ALLGNELVDKRISNTQAVGYSFNFPGWNHLNNASVFNSSHEYKRKRTVGNFASLSLAW
                     KNMLYLNVTGRNDIVSSMPRDNRSFFYPSVSLGWVFTEVEALKNDILTFGKIRGSYAE
                     VGMAGEYVPSYYYTPSYGGGFFQGTPIMYPINGNMAYIPYFVVYDPNLKPQNTKSYEL
                     GADLTFLNGLVSLNYTYSRQNVKDQIFEVPLAGSTGASSMMMNGGKMHSNVHEITLGI
                     SPVDTKNFKLDFAFNFSKIDNYVDELAPGVESIMLGGFVTPQVRAGIGDKFPVIYGVG
                     YKRDGEGRIVVNEKGIPEAGETQVIGKVSPDFRLGFNTNIELYKFRLAAVFDWKQGGQ
                     MYSGTAGETNFYGTSKLSGEVRKSDKYHFDYAAVEQKGVDADGKPIYVPYTGGVKGSD
                     AEEYFKSVRGIDEAYVYDNSFLKLRELSLSYPVYKKDNLNVNVNVFARNIIVWSEIKG
                     FDPEATQGNNNMAGAFERFSLPGTSSYGFGVNVNF"
     gene            15191..16759
                     /locus_tag="ACZPB4_05455"
     CDS             15191..16759
                     /locus_tag="ACZPB4_05455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008771706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SusD/RagB family nutrient-binding outer membrane
                     lipoprotein"
                     /protein_id="HIR1097702.1"
                     /translation="MNTIIKSFKGLAVMSAVSLALAGCSEDVMDRINQDTSHTNSVDG
                     KFILADLITSTAFSNVSGDFNTYSSSYVEYEVGIENQLYNAEIRLNEPSASSTFENTW
                     GNVYTSLKNARVIIGQCQEGKRDEGNLVTRGIAEVMEAYNGALLADIFGDTPYSEASL
                     LDENGSPVNMNPKIDKQEEIYVSIMASLDKAIEDLNQSDRSPVGTYDYLYNGDAEKWI
                     KFAYGLKARYTMRLINRSTDKQADLNKVLDYVSKSFTSADDEAAYAVYDANNINPFFG
                     YFDSRAGFANSQSLTDKLIERKDPRLERVMLSPTTADKKRVQVTGSADKNLVPAPNGT
                     PEQNMQKYGVSAFVYSNTAPTMLMSYHELKFLQAEALCRLNRTSDAEKALKEAVAAGI
                     ANAERSVSSAITYMGSKMVVNSEKMTEETANTYFENQVKPLFAVNPLKETMIQKYLAL
                     WGASGEATETFNDIRRMKGLGENFVTLANTKKFPLRMPYGNSDVVSNPEVKAAYGDGQ
                     YVYSEPVWWAGGTR"
     gene            17241..18512
                     /locus_tag="ACZPB4_05460"
     CDS             17241..18512
                     /locus_tag="ACZPB4_05460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HIR1097703.1"
                     /translation="MMSQPLAERLRPKTLDDYIGQKHLVGQGAVLRKMIDAGRVPSFI
                     LWGPPGVGKTTLAQIIANKLDAPFYTLSAISSGVKDVREVIEKAKSNRFFNTVSPILF
                     IDEIHRFSKSQQDSLLNAVETGVVTLIGATTENPSFEVIRPLLSRCQVYVLKSLDKND
                     LLTLLHKAIAEDVVLKDKNIRLTETDAMLRYSGGDARKLLNILELVVSAEESDDIEIL
                     DEKVVERLQENPAAYDKGGEMHYDIISAFIKSIRGSDPDGAIYWLARMVAGGEDPEFI
                     ARRLVISASEDIGLANPNALLLANACFDALKKIGWPEGRIILAETTVYLACSPKSNSA
                     YMAINDALALVNRTGNLPVPLHLRNAPTKLMAELEYGKEYKYAHDYENHFVKQEYLPK
                     EILGERLWKGQENPAEHKLIEQMRRLWGDRF"
     gene            18645..19712
                     /gene="serC"
                     /locus_tag="ACZPB4_05465"
     CDS             18645..19712
                     /gene="serC"
                     /locus_tag="ACZPB4_05465"
                     /EC_number="2.6.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0004648 -
                     O-phospho-L-serine:2-oxoglutarate aminotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006564 - L-serine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoserine/phosphohydroxythreonine
                     transaminase"
                     /protein_id="HIR1097704.1"
                     /translation="MKKHNFYAGPSILSEYTIKNTAAAVENFAGMGLSLLEISHRSKE
                     FVAVNDEARALIKELLDVPAGYEVVFMGGGASMQFCMVPYNLLNKKASYLDTGTWASN
                     AIKEAKLFGEVDVVASSKDKNYTYIPKGYAIADDSDYFHFTSNNTIYGTEMRKDPDVK
                     QRLVCDMSSDIFSRPIDISKYDIIYAGAQKNLAPAGVTLAIVRVDALGHVDRPIPTML
                     NYATHIKKDSMFNTPPVLPIYAALQTLKWYKEQGGIAAMEKKDLENAAILYDEIDRNK
                     LFRGTVAEEDRSIMNVCFVMNDEYKELEDEFSKYATAAGMVGIKGHRSVGGFRASLYN
                     AMPKSSVEALVACMKEFEKQH"
     gene            19730..20653
                     /locus_tag="ACZPB4_05470"
     CDS             19730..20653
                     /locus_tag="ACZPB4_05470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HIR1097705.1"
                     /translation="MAKILVATEKPFAAVAVKGIREVVEGAGMELALLEKYTEKAQLL
                     DAVKDADAVIIRSDKVDAEVLDAAKNLKIVVRAGAGYDNVDLDAATAHKVCVMNTPGQ
                     NSNAVAELVFGMLVYGVRNFYNGTSGTELKGKKLGILAYGNVGRNVARIAKGFGMEVY
                     AYDAFCPASVIEADGVKAVASTADLFKACQIVSLHIPATAETKGSINFELMNSMPKGA
                     IVVNTARKEVMDEAGLAKMLEERPDFKYLTDIMPAIHAELAEKYAGRYFSTPKKMGAQ
                     TAEANINAGIAAAKQIVDFLVNGNEKYRVNK"
     gene            20725..21972
                     /locus_tag="ACZPB4_05475"
     CDS             20725..21972
                     /locus_tag="ACZPB4_05475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016273508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1015 domain-containing protein"
                     /protein_id="HIR1097706.1"
                     /translation="MAKIKPFKGVRPPKEFIEEVASRPYDVLNSQEARAEAEGNEKSL
                     YHIIKPEIDFPEGTDEHDPAVYLKAAANFNNFQEKGWLVQDQKECYYVYAQTMNGKTQ
                     YGLVVGAYVPDYMNGTIKKHELTRRDKEEDRMKHVRVNNANIEPVFFAYPDNSELDAI
                     VMKYTAREPEYNFVAKLDGFGHTFWIIDEDKDIARITELFGEMPALYIADGHHRSAAA
                     ALVGAEKAKQNPDHKGDEEYNYFMAVCFPANQLTIIDYNRVVKDLNGLTEEQFVERLT
                     KNFVVEEKGSAIYKPGALHNFSLYLGGKWYSLTAKPGTYDDNDPIGVLDVTISSNLIL
                     DEILGIKDLRSDKRIDFVGGIRGLGELKRRVDSGEMKVALALYPVTMKQLMDIADTGN
                     IMPPKTTWFEPKLRSGLVIHKLD"
     gene            22095..22726
                     /locus_tag="ACZPB4_05480"
                     /pseudo
     CDS             22095..22726
                     /locus_tag="ACZPB4_05480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865363.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
     gene            22765..25146
                     /locus_tag="ACZPB4_05485"
     CDS             22765..25146
                     /locus_tag="ACZPB4_05485"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hybrid sensor histidine kinase/response
                     regulator"
                     /protein_id="HIR1097707.1"
                     /translation="MTNTTLNLEELLCGVNELVDTLWIVTLGNEKVEIVKDSMTPERE
                     GECLDYTELCQTYIQEYVYPADLGKWEEILSLNSLRQMAASGVANKKFDMRFCNDLLG
                     FEWHEAFIRILKDKSGIPDRVILFSRYVNHCRKAQIVEAAVQTEYDYVVYIEANTNSY
                     VMYTSNRESGMPVPPIASNDYEKEVAEFHHKYVPEDQRDELTRNLSLDHVLSILQNSR
                     EYVLFCQVMENGVFRDKKLRFSFFDKERNILLLTRTDIMEVREEERQRQLLQDALQVA
                     KSANQAKSDFLSRMSHDIRTPMNAIIGMTTIASMHIDDRERIVDCLKKIMVSSKLLLN
                     LINEVLDMSKVESGHILLTDEEFDMGELLQSVITMVQTSVSQKFQDFRVHLFQIKHEK
                     LIGDVQRIQQVLLNLLSNAIKYTPDYGKITLEIREKPIKNGNYGLFEVTVIDNGIGIK
                     PDFLHKVFEPFERAEDATLRNIQGTGLGMAISRNIAHMMNGEILVESEYGKGSVFTFT
                     MQLKLQDQGCFEDDHLRDLPVLVVDDDIVCCENACMRINEIGMKGEYAISGEEAIGKV
                     ERAHHLNDDYFAVILDLKMPGMDGIETATRIRKVVGRDIPIIILSAYDCPHFEEIAQR
                     AGVDGFISKPLMKSKLFYLMKSFAIKQEEKEEETEKPQYPFGNFEGKRILLVEDNSLN
                     REIATVLLEETGAVVEEAENGLVAVNMVKNSSPGYYDLVFVDIQMPVMNGYDSTRHIR
                     ALERPDIKSMPIIAMSANAFAEDIKLCKESGMNEHIAKPIDFGKVLEILEKYL"
     gene            complement(25215..26255)
                     /gene="galE"
                     /locus_tag="ACZPB4_05490"
     CDS             complement(25215..26255)
                     /gene="galE"
                     /locus_tag="ACZPB4_05490"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005778195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HIR1097708.1"
                     /translation="MKKKILVAGGTGYIGSHTTVELQNAGYEVVIIDDLSNSNIEVLD
                     GIEKITGIRPEFIQLDLKDKEGTRKALEAHPGIKGIILFAASKAVGESVQQPLKYYRN
                     NIVTLVNLLEMMPEFNIEGIVFSSSCTVYGQPDPENLPVTENAPIKPAMSPYGNTKQI
                     NEEIIRDTIHAGAPFKSIILRYFNPIGAHPSAEIGELPNGVPQNLIPYLTQTAMGIRK
                     ELSVFGDDYDTADGSCIRDYINVVDLAKAHVIAMDRMLENKSDEHIEIFNLGTGNGVS
                     VLELINTFEQTTGVKVPHKIVGRREGDIEKVWANPEHANKVLGWTAKETLADTLQSAW
                     NWQKRLRERGIQ"
     gene            complement(26281..26853)
                     /gene="rsxA"
                     /locus_tag="ACZPB4_05495"
     CDS             complement(26281..26853)
                     /gene="rsxA"
                     /locus_tag="ACZPB4_05495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002562594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxA"
                     /protein_id="HIR1097709.1"
                     /translation="MEYILIFIAAVFVNNVVLAQFLGICPFLGVSKKVETAAGMGAAV
                     TFVLTIATIVTFLVQKYILDAFGLGFMQTISFILIIAALVQMVEIILKKVSPALYQAL
                     GVFLPLITTNCCILGVAILVIQKEYNLLESVVYAISTAIGFALALIIFAGIREQLAMT
                     HVPEGMKGTPIALITAGLLAMAFMGFSGIV"
     gene            complement(26866..27450)
                     /locus_tag="ACZPB4_05500"
     CDS             complement(26866..27450)
                     /locus_tag="ACZPB4_05500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005841504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit E"
                     /protein_id="HIR1097710.1"
                     /translation="MSNLKILMNGIITENPTFVLLLGMCPTLGTTSSAINGMSMGLAT
                     MFVLICSNIVISALKNVIPDLVRIPGYIVVIATFVTVVQMCMEAFVPALYASLGLFIP
                     LIVVNCIVLGRAEAFAAKNGVIPSAFDGIGIGLGFTMALTLLGACREFLGTGKLFNVT
                     LMPEEYGSLIFVLAPGAFIALGYLVAIVNKLRKA"
     gene            complement(27468..28082)
                     /locus_tag="ACZPB4_05505"
     CDS             complement(27468..28082)
                     /locus_tag="ACZPB4_05505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit G"
                     /protein_id="HIR1097711.1"
                     /translation="MAKLKSTLPNMLLSLTGICLVAGAILAGVNQFTAGPIAVAKATA
                     LEEAIKAVAPEFDNKPTEDVYMAVSSDGDSLKIYPAKKGGQVVGGAVESNTKKGFSGE
                     IRVIVGFDMDGKILNYSVLQHAETPGLGAKMQEWFRADKNKQSVLGRTIPDGGLKVTK
                     DGGDVDAITAATISSRAFLDAVNRAYSAFAGVDGLTGATSTDNK"
     gene            complement(28085..29053)
                     /locus_tag="ACZPB4_05510"
     CDS             complement(28085..29053)
                     /locus_tag="ACZPB4_05510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit D"
                     /protein_id="HIR1097712.1"
                     /translation="MENNLYVSPSPHIHGGDSISKNMYGVLIALIPAFLVSLYFFGLG
                     ALIVTVVSVLACMIFEYLIQRFLMKKEPTLCDGSAILTGVLLAFNLPSNLPVWIIIIG
                     ALAAIGIGKMSFGGLGNNIFNPALVGRVFLLISFPAQMTTWPVVDALNVFPMTYTDAQ
                     TGATVLSLMNEGVTELPSYGNMLVGAMGGSLGEVSALALILGLLFMLWKKIITWQIPV
                     SILATVFVFTGIMHLVNPVQYASPFVHLLSGGLLLGSIFMATDYVTSPMSKNGMLVYG
                     VGIGILTTVIRLFGSYPEGMSFAILIMNAFTPLINSYIKPKHFGGK"
     gene            complement(29066..30397)
                     /gene="rsxC"
                     /locus_tag="ACZPB4_05515"
     CDS             complement(29066..30397)
                     /gene="rsxC"
                     /locus_tag="ACZPB4_05515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005641291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxC"
                     /protein_id="HIR1097713.1"
                     /translation="MLRTFRIGGIHPPENKLSAGKKITALATPKQVIIPLSQHIGAPA
                     QAVVKKGDLVKVGTLLAKAGGFVSANIHSSVSGKVNKIDNALDASGYKRPAIYIDVEG
                     DEWEETIDRSETLVKECTLSSKEIVDKIAASGIVGLGGATFPTQVKLMPPPGNKAEIV
                     IINAVECEPYLTSDHSLMLEKGEQILVGVTILMKAVNVNKAVIGIENNKPDAIAHLQK
                     LAVNYKGIEIMPLKVQYPQGGEKQLIDAVIRRQVKSGALPISAGAVVQNVGTAYAVYE
                     AVQKNKPLFERVVTITGKAVANPSNFLVRMGTPISCLIEAAGGLPENTGKIIGGGPMM
                     GKALISAEVPVCKGSSGVLLLTTEESVRKPIRDCIRCAKCVGVCPMGLNPTLLMNATE
                     FQNWELAEKNYITDCIECGSCSYTCPANRPLLDQIRLGKGKVMGIIRSRKS"
     gene            complement(30409..31341)
                     /locus_tag="ACZPB4_05520"
     CDS             complement(30409..31341)
                     /locus_tag="ACZPB4_05520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008771711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster domain-containing protein"
                     /protein_id="HIR1097714.1"
                     /translation="MILIAVISLGAIGAVGAVFLYAASKKFEVYEDPRIAQVQEVLPG
                     ANCGGCGYPGCAGFAGACVKADSLDGLLCPVGGGPVMAKVATILGKEAGTAEPMVAVV
                     RCNGTCQARPRTNSYDGTKSCAIASTLYGGETNCSFGCLGYGDCVNACAFDAIHINPA
                     TGIAEVDEEKCTSCGACVKACPKNIIELRKKGPKSRRIYVSCVNKDKGAAARKACANA
                     CIGCGKCAKECPFEAITVTNNVAYIDYTKCRLCRKCVAVCPTGAIHELNFPPRKEAAP
                     APKAETVKPAPKAEATVKPEATPKVTSEEKTNLN"
     gene            complement(31351..31767)
                     /locus_tag="ACZPB4_05525"
     CDS             complement(31351..31767)
                     /locus_tag="ACZPB4_05525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SoxR reducing system RseC family protein"
                     /protein_id="HIR1097715.1"
                     /translation="MSESINHTGFVEKIDGDTVFVRITQQSACSGCHAQSMCSASEKK
                     DKIIEVPDRSGRFHVNEEVIICGQNSMGLQAVLLAFVIPLVIVVGAIVIGTNLQWDET
                     TSGLTGLSLLLPYYCILYLMRDKLKRRFIFTLKKLN"
     gene            complement(31869..33413)
                     /locus_tag="ACZPB4_05530"
     CDS             complement(31869..33413)
                     /locus_tag="ACZPB4_05530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3078 domain-containing protein"
                     /protein_id="HIR1097716.1"
                     /translation="MMMKRHGVYALLLLSLIGGSAYSQENQLVTGTIVQRPAQQVVSD
                     DTIPAINLSEEELDNIVDIRKQFEKQNKTYSAPLAPSTNLLRFLKKDELEISDEAMYW
                     ARLVRDASTIFDNTMTFRDTVIVNPLFMPIVFRGDYLPENLIFYNFDSLKERTPYDNL
                     YRADSIFKDLERNKQFEEMAYKYVQNNYPTYFRYSERDLPNEVIKPKFIKKNIYEDLP
                     IKVEADANFEDVDAPARFIPERRYWISAFESAVQFSQNYVSENWYKGGSSNLNLFTKN
                     NLKYDYKKDKVQVTNELEFKASVYTAPKDTLRNYKIGDDVFRIHSNVGYQAFNKWYYT
                     FDAEFKTQFFTNYQENERIKQAAFLAPFSINFGLGMKYELEKQFTDKHKKIKFSTNLA
                     PISYTYMYTTQEIDYSRHGFKKNEETGEFNNKLSQIGSTIRADLAFDFNRNVSWQSRL
                     YFFTTYGDHTIGEFENTLVLAISRFFSTRIYFHLRYDDGVEKTEDNKSYFQLNELLSF
                     GFNYKW"
     gene            33831..35438
                     /locus_tag="ACZPB4_05535"
     CDS             33831..35438
                     /locus_tag="ACZPB4_05535"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008150588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003883 - CTP synthase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006241 - CTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HIR1097717.1"
                     /translation="MADTKYIFVTGGVVSSLGKGIISASLGKLLQARGYKVTIQKFDP
                     YINIDPGTLNPYEHGECYVTVDGHEADLDLGHYERFLNVQTTRANNITTGRIYQSVIN
                     KERKGDYLGKTVQVVPHITDEIKRNVKLLGSKYKFDFVITEIGGTVGDIESLPFIESV
                     RQLKWELGKNCLCVHLTYVPYIAAAKEYKTKPTQHSVKQLQELGIQPDVLVLRTEHEL
                     NANLLRKVALFCNVAEDSVIQSIDVPTIYEVPLVLQRQKMDEVVLRKVGMEVGPTPEL
                     KPWKEFLALKSTATDTVKIGLVGKYVELQDAYKSIDESLLQAAIYNHHKLDLHLFHSE
                     KLNNENAAEQLKDMDGILIAPGFGQRGIEGKFAAIKYAREHDVPCLGICLGMQCMVIE
                     FARDVLGLADANSTEMEPNTAHKVIDLMEEQKNVTNMGGSMRLGAYDCTLKEGSKVLE
                     AYGKEHIQERHRHRFEFNNEYKKQYEAAGMMCTGENPETNLVEVVEIPALKWFVGVQY
                     HPEYNSTVVNPNPLFLSFVKAAIENKK"
     gene            35449..37350
                     /gene="yidC"
                     /locus_tag="ACZPB4_05540"
     CDS             35449..37350
                     /gene="yidC"
                     /locus_tag="ACZPB4_05540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0032977 - membrane insertase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HIR1097718.1"
                     /translation="MDKNTLIGFLLIGVVLFAFSWFNRPTPEQLEAQRRYQDSIAKIE
                     YAQQLELQKQENKSALVEDSLENLPDSVRAQRLQQSFGVFGDAMVGTEDYTTLQNDVV
                     ELRISNKGGRICYARLKEYDTYNDEPLVLFDEKESNFNFTLVTATNRVVNTSDLYFTP
                     VKGNDPNSVIMRLNTGEGSHLDFTYTLKPDDYMVQYQILGTGLNGVLAPSTNALDLLW
                     EQDIRQQEKGRKFEDRYVTLNYKFMADDVEHLSESKSDSKQIPNRLKWIGYKDMFFST
                     VLISQEGFEATTLDSKAIPEGDVLKQFKTTASVPFDLQGKETTNLSFYFGPNKFALLK
                     SFDKGVSAEQQLDLEKLVPLGWGIFRWVNQYFVIPLFDFLGKFIHNYGILILLMTIIV
                     KIILFPLTYKSYMSSAKMRVLRPQVEEINAKYPGQDKAMERQKATMELYSRAGASPMS
                     GCLPMLLQMPILIALFMFFPSAIELRHQSFLWAHDLSTYDAIFSWNKYIPIITPYFGN
                     HISLFCLLMTITNIFYTKYNMEMTNTGQQQMPGMKAMMYMMPLMFLVFFNQYASGLTY
                     YYFISTLITIVQTLIFRYTINEDKLLAKLEANKRKPMKKSGFMKRLEEAQRAQQETLR
                     KQQEAKKKR"
     gene            37600..39324
                     /locus_tag="ACZPB4_05545"
     CDS             37600..39324
                     /locus_tag="ACZPB4_05545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6057 family protein"
                     /protein_id="HIR1097719.1"
                     /translation="MTKNERSLQWVIAGIFFVVCFAFFQWIYPNHLFFKEQMRIFLYT
                     TDYFISFWDEPAWLSCYVGNFLIQFFHLTVIGPLIVTCVLLLLWYYSMRVLRKFGNGN
                     MVSIYALFPVALEWGLICRLSYSIASTLTLIFVLWLFLGYIRIKNKRTSVWVAFILLP
                     IIYSMVGSRLFVFSLMVIFYEGAKNRKRWWFWLSLLLSSYLYPLFMRHFYGLSIEEAY
                     KYSHVDGLSVYFPALALILEIFALEIKSIRRIRLNRHSLLITFLVVFGFFSFVIAGTN
                     RKREKVLAVDQAIYRGDWERVLDLSAGFDSPDILVSYYRNIAFSKKNELPQNLMDHYQ
                     RGADALFLPIDLRSSILPVFFSNEVYYQLGDMDMARHRAIEGILFSPKQRSVRQIKRL
                     VEIDMRRGDIEEARKYLNLLDATLFYHSWARSKEEQLKGEETLSMEKRLPRKSDWERE
                     HDILMSISDYPGVLSSLMAEYPENKQALDYLLCYYLLNENLNSFKNAFDTYYKGKFEV
                     VPRLYEEALVQVLSKSSDEEVAGYQIPQDVIENYQDYIHCKSGRKAKEELRERYSSTY
                     WYYSDYIH"
     gene            complement(39341..40093)
                     /gene="kdsB"
                     /locus_tag="ACZPB4_05550"
     CDS             complement(39341..40093)
                     /gene="kdsB"
                     /locus_tag="ACZPB4_05550"
                     /EC_number="2.7.7.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008690 - 3-deoxy-manno-octulosonate
                     cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0009244 - lipopolysaccharide core region
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-manno-octulosonate cytidylyltransferase"
                     /protein_id="HIR1097720.1"
                     /translation="MKFIGIIPARYASTRFPGKPLADMNGKPMIQRVYEQVKDVLDSV
                     CVATDDIRIENAVKTFGGQVVMTSDQHRSGTDRCYEAYQKIGEGYDVIVNIQGDEPFI
                     HPEQIQTIKTCFADANTQIATLVKPFRSDDDFESTLFNPNSPKVVLNNNNEAMYFSRS
                     IIPYIRGKKYTEWLPSHTFYKHIGLYAYRAQVLKEITQLPQSALELAESLEQLRWLEN
                     GYKIKVGITEQETIGIDTPEDMEKALAFLANR"
     gene            complement(40111..42381)
                     /locus_tag="ACZPB4_05555"
     CDS             complement(40111..42381)
                     /locus_tag="ACZPB4_05555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter domain-containing
                     protein"
                     /protein_id="HIR1097721.1"
                     /translation="MSQIPALISDLAVILISAGLVTLLFKKLKQPVVLGYIVAGILAG
                     PSIEQIPTVTDVESIRIWADIGVIFLLFALGLDFSFKKLMKVGGTAVIGAITVVIGMM
                     TAGYITGLSLGWGHMNSLFLGGMLSMSSTTIIFKAFDDMGLRNQRFAGVVFGILVVED
                     LFAVLLMVLLSTVAVSKHVEGMEMLDSVVKLGIFLLFCFVVGIYLIPSFLKKAKSFLN
                     EETLLIVSIGLCLGMVMIATKAGFSSALGAFVMGSILAETIDAERIEHLVKPVKDLFG
                     AIFFVSVGMLIDPQMLWEYKIPIFIITLVVMAGQICFASFGVLLSGQPIKIAIQSGFS
                     LAQIGEFAFIIAGLGLSLNVTDQYLYPIVVAVSVITTFFTPYMIRLAEPTYKWAERII
                     PENWKQFLERYSSGSNTIRQKSAWNKLLKALVRIVGTYTAVCLVLIFLWLQIVTPFIC
                     KHLPGIQGSLISLILILALISPMLRAIMMKKNHSVEFQQLWNDNKYNRGPLVSLVILR
                     ILLCIGLVMLPVARLLNAALGIMLAVASAVIVLMIFSKRLKRQSILMERHFFSNLVAR
                     EVEQERKAPINQRFANHLLERDLHLADFEVKQNSPSMGKSLKELNFRQKCNVNIVTII
                     RGEKRINIPGGDERLYPFDKLVVVGADDDLEHFRKYLEERYKKSYAEQSNTRKEEMNM
                     EQIIISEGSRLIGRSIIESGIRDKAACLVIGIERGSSSIKNPPPSTVFEEGDIVWIVG
                     ERDKLIQLSEGKVVTS"
     gene            42452..43087
                     /locus_tag="ACZPB4_05560"
     CDS             42452..43087
                     /locus_tag="ACZPB4_05560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AlbA family DNA-binding domain-containing
                     protein"
                     /protein_id="HIR1097722.1"
                     /translation="MKKKHPIEALIEQGEHQQLDFKFEVSDSKKIARTLSAFANTDGG
                     RLLIGVKDNGAISGVRSEEEYYMIEAASKMYTHPEVPFTAKRWDVNGKTVLEVYIAPS
                     DEKPHTAPDKDDKYKAYIRVADENILANEVLMQAWKKQKTKEGTLLKISKPVEILFSW
                     LDEHPYISIKQFCRIAHINYYAARNILSDLMAMGAMEYVVIDKCIAYKRIA"
     gene            complement(43094..44473)
                     /locus_tag="ACZPB4_05565"
     CDS             complement(43094..44473)
                     /locus_tag="ACZPB4_05565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HIR1097723.1"
                     /translation="MKRLLTILTAIVLILAISLQSEAKEKSLIYTIDIKKEIDNTTWI
                     YLHNGLSEAKQLNADAILLHMNTYGGLLESADSMRTAILYSPIPVYVFIDNNAASAGA
                     LISIACKKIYMRKGANIGAATVVNQTGAALPDKYQSYMRSMIRSTAEAQGKDTLIQNG
                     DTIYKWKRDPLIAEAMVDDRVIVPNLIDSGKVLTLTSQEALKWGYCDGIAESPDQVIT
                     EYIGCKDYEIKSYEPSWFDNVKGFFMSPVIQSLLIIIIIGGIYFEMQTPGLGFPSAAA
                     IIAAILYFAPLYMDGLAENWEILLFILGVILIMLEIFVIPGFGIAGISGIILVVGGLT
                     MSLLNNTVFDFQNVSGMDTGRAALTVLLGLGIGFTLVIWLSNKIGHKGPLKKMALNAD
                     LEKAVSSPNLTQLIGKEGTAATVLRPSGKVSIEGELYDGVSESGFIEKGTPIKVVRFE
                     SAQVYVINL"
     gene            44739..45248
                     /locus_tag="ACZPB4_05570"
     CDS             44739..45248
                     /locus_tag="ACZPB4_05570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HIR1097724.1"
                     /translation="MNALQFQKKLLSMQENMMNFALMLTANRDDAQDLMQDTTLKVLD
                     NQEKFVDNINFKGWVLTVMRNIFINNYHKIVRTQTVVDQGVDLYNLDVVNDSGFDSPD
                     GAYQIQEITKAINGLNNELKVPFSMFLSGYKYNEIADKLDVPLGTVKSRIFFARQELQ
                     KVLKDFRQG"
BASE COUNT        12467 a         9185 c        10606 g        13001 t
ORIGIN      
        1 ttggtgcgtc tgtaatagtc aagggtacta ctacaggtac agtaacggat tttgatggtg
       61 tgttcagttt ggatgtacca agttccgcga agactctggt aatttcttat gtgggtatga
      121 ttgctcgtga ggttccggta caagatgtgt tgagggtagt ccttcagtct ggtacccaga
      181 atcttgagga ggttgtcgta actgcgattg gtatgaaaaa gcaggaaaag gcgttgggct
      241 atgcagcctc tactgtgaag agtgaagatt tgaatgccgc taagtctgga tcagtgatgt
      301 caggtttgac tggtaaggtt gcgggtttga atattactag cggtggtgct acaggctctt
      361 ctcagaaagt aatcgtgcgt ggtatcagtt ctttcagtgc taatcaacct ttgtatgtgg
      421 tggatggtgt gcctattatg aatgatttcc aaggtgagga ttctttctct aactccgtgg
      481 attttggtaa ccaagctaat gacattaacc cagaggatgt tgagtctgta acagtcttga
      541 agggtgcttc cgctactgcc ctttatggta gccgggctgc taatggtgtt atcatggtga
      601 caacaaaacg ggctggggct gagaggcttt ctgttacgta cgatggctca tttatgggat
      661 ctagcgtatt gcgtgttcct caaacacaag atcgtttcgg acaaggatgg ggatctttcg
      721 gacctatgga gaatggttct tggggaccgg ttttggatgg tcgtgatcat atctggggac
      781 cttactcaga cggctcagaa ggtttattaa ctccgctttc taagcctttc tcgtatgtaa
      841 agaacaatct tcgtgatttt tatgaaactg gttttgagac gaataataac gtctcgattc
      901 gtatgggtaa tgataaactt ggttttgttg cctcctatgg taatgtgaag tctgacggtg
      961 tattaccggg tgacgctgat tcatatgctc gtaatacaat ctcgttaaga ggtaatatga
     1021 aatataaacg tttttctgcg gaattaaact tgaactatgt ccgtaaagat atcacacaag
     1081 ctgctgctgg ccaaggagat gatggtgcaa cgatgttttc tgagattttg caacatgccg
     1141 tggatgtaga tattagctca atgaaagatt atacgaatcc ttattttaat acggataact
     1201 tctatacagc ttatgcggag aatccatatt gggtgttaga tcataatcgt aataagtatc
     1261 aagatgaccg tgtctatggt aagatcgagc ttgcttttga gattatgaaa ggtttgaagg
     1321 cggttggacg tttaggtggt gactttacga acgctactca aaagagatgg aatgaaaaag
     1381 tgactttcgc ttcagggtct tggagtgaat taggtggtaa gaagcagcag cccggtactt
     1441 atacggaacg tcgtgacaag gtggagcaaa ttgatgcgac cgctttctta aacgcggatt
     1501 ataaaatcgg tgaggatatc gctttgaatg gtatgattgg atggaacttg aatcaacaaa
     1561 caagttctta tttgaaatct tatctgtatg gtttggagca accgggatgg tttaacttag
     1621 cgaatggtgt tgataagccc atgactacga cttactctga tagacgccgt ttggttggtt
     1681 tgttcgctca aggtgagttt ggttacaaga atttctggtt tgtgaatgct tctattcgta
     1741 acgactggtc atctacttta cctcaaggaa ataatagctt tttctatggt ggcgtgaata
     1801 cttcattgat catcacggat atgtttgagg atttgaaatc tgattatctg aatttcttga
     1861 aggttcgtgc agcttgggga cagactggta acgatgctcc gatttaccgt actagcagtt
     1921 attttacacc gactcaaatc agtttaggtt ttggagattt atatttacct attaataata
     1981 cattaggctt gacagagtat aatcgtttgc cgagtatgga tcttcgtccg gagattacga
     2041 cagaatggga gttcggttta acaacgcatc tgtttaacaa tcgcttggat attgatgctg
     2101 cttattataa taagagtacg aaagatcaga taatatctgc tagtctggct ccggagtctc
     2161 gctatacgtc tatgacccgc aacgtaggta agattgcgaa tcaaggtgtc gagttggcag
     2221 tgaatggcat tcctgttcgt acgaaagatt tcgagtgggg attaggtttt actttcagta
     2281 agaactggag tgaggtgaaa gagttatggg atgatgtaac tgagtataaa ttgacaagtt
     2341 cctatcaagt ggatttcgtt gcggaagtag gtcagccttt gggcgttttc aaggttccgg
     2401 ctttggccac gactgatgat ggtaaggtga tcgttgataa taacggtatg ccgacaattg
     2461 atgctagcaa gaaagagatc gtaggaacgt ctacacctaa tttcttgatg ggctttaata
     2521 cgcatttcac atggaaaggg attactttat cagcggtatt agattggcgt aatggcggtg
     2581 agttctattc atatacctct caattgctta catttgccgg aaactctact tatacggtgt
     2641 ttaataatcg tgaaccattt gtggttccta attccgtgaa agtcgtaaat ggtcaatacg
     2701 tagagaatga tatacctatc gtacattggg gaggtgcttc tagcgctgtt aatacctact
     2761 ataataacgc ctccaactac gctcagtata gaaattggat tttacctaaa gattacttga
     2821 aattaagaga gattacactt tcttactctt tgccgaaagc atggttgaaa caaaccccat
     2881 tctctatggt tcaagttagt ttgatcggac gtaatttatt tatgtggacc ccgaaaaaga
     2941 acaactacgt agatccggaa ggtacgaatt atggtaatga catcttgtct gaaattggtg
     3001 aatttggtgc ggctccgaca aaccgtacgt ttggtggtgg tattaaagtt gtattataat
     3061 aagtaacttt aaaaagtaaa gatagtatga aaagaaacaa tttaatatat acaggactgg
     3121 ttagctgctt gttgatggcg actacagctt gttccgatta tttggatatt aaccagaatc
     3181 cggaatatcc aacggaagcc tcttcttcta ctttgcttcc ttctggtatc gcaggagtag
     3241 caagtattgt aggtggtact tacgaattat atggtagcat gtggtctcag caatgtacgc
     3301 agggacatac atccaaccag tataatacat tggttaacta tacgataact aacgcatccg
     3361 attctcgttt gtggtctata ccttattcaa tagcactgcc agacttggat ttggttatca
     3421 aaagctctga atcggctcaa gaatggaatt attgggtaat gggtaagact atgactgcct
     3481 ttatgtatca tatcctagtg gactcttatg gctctattcc ttttacagaa gctattcttg
     3541 ggaatgagaa tactacaccg aaatatgatg acagtaagac tgtggtttat ccgggattat
     3601 tagcgatgtt ggacgagatt atcgctaaaa aagcggaagc taccgcaggt ggtttgcctt
     3661 cggttacaaa acaagacttg gtgttcgctg gtgacgtgaa taagtggatt caatttgcga
     3721 agagtttaaa gctaaaattg ttgatgcgtg atttcgatac gaataaagct gctatcaagg
     3781 cattgctcga cgaaggagat ttgctgagtg tagacgctaa gatggactgt tttcaagatt
     3841 tggaaaataa atcaaatcca ttgtatgaga atgaccgtcg taaattgaat tcaactgtaa
     3901 atattcgtgc gtgcgctacg gtttgcgatt atttgaaaaa atatgaggat cctcgtttaa
     3961 atgattttta ttcacctaat acggatggct ccggcgagac aacagctttg aagtatggtg
     4021 accgcccaaa ctcggtagcg gtaacaactc gtatgatctc tgtggctaag ctaggtccta
     4081 cagatcctgt ttattttatg tctgctgctg aggtagcgtt cctgcaagcg gaagcttacg
     4141 ctcgtttgaa tgatgtggct aaagcgaaag tggcttatga gcaaggtgtg aattatgcgt
     4201 ttgaacgttg ggggtattct gctgccgagt ttgtttcgga aggtgctcct tatgctttcg
     4261 atagtacgga ccaaaattca atgcttacct ctattttgac ccagaagtgg atcgcttcca
     4321 ctcgttgtca agcatgggac gcatggtttg atatcaatcg taccggtatt cctgttttag
     4381 ggacaaagca tgtggatgag gaaggatata tttgggggca gttgactcct tgcattggtt
     4441 ctgcgttggc tccgggtgaa tatcctcgtc gtttattgta tccgaagtca tcttcagact
     4501 ataaccctaa tactccggcg gtagttccgt tagcggaaaa acaatggtgg cataaataaa
     4561 tgggtgttat aaatgtatat taatcagaaa agctttttga atatgaaaca gataaataaa
     4621 ttactggtta tcttattggc gttggtcacc ttttcttctt gtgagactta tggtgattac
     4681 gagatagaat acacggctat ttacccttta tgtggcgaat gggtagttaa tgttacaggt
     4741 gaggatggtg gtgtcttggc ggaaggtgtg acctgcaata cttacaatac gactgatgat
     4801 gccacggata agatgtggat aaaaatgagt gttgccacaa acgactgggg agtacgtggc
     4861 aagattcatt gcgatgtcac ttctaaatct tttgatgggg atggtatcgc taatctgctc
     4921 catgcggatg atggtataaa ttctactgta accttcaata tctctggtaa agtaattgtg
     4981 gatggttata ctactcaagc caatacaaaa gtggatgcca ttgaatttac cttgactcaa
     5041 aatggaaagt cgatgacggt taagggattc cgtaaaacag gttgggaagg tgaagattat
     5101 tgatatgatt taatatctcg aaaagtagga gaggcctgcc atgtatttgg taggcccttt
     5161 ttatttactt ggatatatgg ttttttatta gtaggtaatc cgtgataaca aacttttagt
     5221 ttgtagattg tgctacaaag aacttattat tgttccttcg tgtttacaat cagataatat
     5281 ataaatgtat catggaaaag gtaatttaca acttagtgtt taatcgaaaa aagcaattga
     5341 atgcggaagg aaaagctttg attcaagtag aggcctattt gaataggcaa aagaggtatt
     5401 tttcaacgaa ggtttatgtg aaaccttgtc aatgggacaa caagagacgt tccataaaga
     5461 atcatccgaa tatggatgcg ttaaacctgt atcttcagaa ctatgttatg gagttggaga
     5521 gagatgagct ggagaagaga caagcgaata acggtttttc gttgaaggat ctgcgtgagg
     5581 aggcttcttc gacatctacg tcttcctctt ttcttgtttt catgcgtgag gagattttac
     5641 atagtaattt gaaagaatcg acattaaaaa accatttgtc cactttgcat gttctatcct
     5701 tatataaaaa ggacgttctg tttaaggata ttaatttcaa tttcttatgc gattttgaat
     5761 atttcttatt gaagcaggag tatcatcgaa atacgatcgc taaacatatg aagcatttga
     5821 aacgatatat caacttggcg attaataagg agttgttcga gttgcacaaa tatccatttc
     5881 ggaaatataa gattaaatat caagagagta agcgtactca tttaacgcct gaggagttag
     5941 gtcgtttgga aaacttaaag ctggatgggc agcgtacatt gcgccggtgt ctggatatgt
     6001 ttttatttag ttgctacacg ggattacgtt tctcagacat agtaagtata acgaaagaga
     6061 actttttgat tattgatgat aaggtttggc tggtttattc atcggtgaag acagatgtga
     6121 gtgtccgttt gccgctattc ctcttgttcg agggtaaatc tttacctatc tatgagcgat
     6181 ataagaatgc gccgagaacc ctgtttggtg ttcccttatc ctctaattca aacgtgaata
     6241 agcaattacg ccgaatcagc caattggcaa gtattgataa gaaggtatct tttcatacgg
     6301 ctcggcatac aaatgctacc ttattattat ataatggagc gaatataact acggtacaaa
     6361 agttgttagg gcataaaagt gttcgtacta ccgaaatcta tagcaatatc atggatatga
     6421 cgattgtccg cgatcttgag aagattgaga cacgattgaa gttcggctag aatgtggatt
     6481 tataagaaag gagaaaaata tcattaagat attcttcccc ttttttgaat gttgtcactc
     6541 gttatgcttt tatatattga ttagcgagtt ccgccagccc accatacgtt ttcggtaaac
     6601 acatactgac catcaccata agcagcttgt atattaggat tagtcgtagt atcatcatta
     6661 ccatacggac atcttaacgg gaacttaccc ggattttgca agccataaat atcctcaccc
     6721 aagctcttca aacgacgtac gtcattatag cactcggtag actctccatc tgcgttccag
     6781 aaagaaatat atttctgaat catcgtctct ttcaaaggat tagcatcgaa taagggaacg
     6841 acattctcat caaagtaaga agcggcctcc tccggtgtca cctcgtttgt tacattcaag
     6901 aaacctcccc aataatcaga agcgagggca gacttgatat taacctccat attagccata
     6961 cctgcgacaa cagcctcttt caacactgct tttgcctcat ccttacgatt taaacgacac
     7021 aaagcctctg ccttcaagaa caatacctca tgataactta agatgtgagt cggagcggtt
     7081 tgagctgcac agaacatgga aacagtatat tctaactgac tttgcactaa atcaccatta
     7141 tgagcaagat tcaataatgg atcatcctta gaagcaatca tcgtttggct gttagcctcc
     7201 acatagcaac gtctgatacg cggatcatta cgctcattca atttatcaaa catacttcgg
     7261 ctggctactt cacctaaacg agaatagaat actccgaaaa atgggttgat attaacaccc
     7321 acaccataca tagcatagct acattgctcg gctgccgagg tgtacgactt ggaaatataa
     7381 tccaacacct tttccatatc gcccttaaca tcagcgctac gtcccatcaa gcgcatcgta
     7441 taacgagcct tcaagccata agctgtcttt agccaagccg aagcgtcacc tttataaatc
     7501 aaatcttgat tagacaggct cgtcagatct gatttctgaa gatcttcaat tgcggcatcc
     7561 acataggcca tgatatcctt ataaatctcc tcttgtttat cgatagcggg agtcatagat
     7621 actgtatagt cacaagcctc tttccaaggt gtatcaccat acatatctgt caagatcgcc
     7681 aaattgtaag ccacgaaaag ttccgcaatg ccttttgtta tgaagttctg ctcttcttct
     7741 gcgactttga cagagatcaa agcatctttc agtgtcgaat aggttccccc ccatgagtta
     7801 ttaaaggtag aagccgatgt acaagaagaa cgggtttccg catagtagaa ttgattatgc
     7861 gaacctgtct catgttccac atacatacca ccatataaat tgaaatcgcc gctaaccacg
     7921 ctaaacgcag tcgaagtcat gacatccgta aggatcatct ttgcgggaac tgctgtggta
     7981 tgattatgat ctttgttgat ctcatccatc ttatcctcag agcaagagac caaggctgcg
     8041 gtgaaaacaa ctcccgtcaa taattttttt gagatatttt gaagtttcat cttttgtttc
     8101 ctttattaga atttcacatt taaaccgaag ccatagctcg aagcacccgg catagaaaag
     8161 cgctcgaagc caccgcccat attattatta ccttgagaag cctcaggatc caaacctttc
     8221 aactcagacc aaagaatgat atttctggca aaaacattta agttcacgtt gattccattc
     8281 ttatcccata tcggataact aacggacaac tcacgtagtt tcaagaaacc actgtcatag
     8341 ataccggctt cggaaataag cgtcatgcgg tcataatatg ataaagcgtc ttcgcctttg
     8401 atatctatgt cattagctac ataggaacca tcttccaact gctttacagc cggatgacta
     8461 aaacggaaag tctcggccgt acgactttca acagactcca tacttgtacc ataatagttc
     8521 aacgtgttca atgtaccgct atacatctgt ccaccacatt tccaatcgaa cgtagcgccg
     8581 atacggaatt tgtagatctc aaaattagta ttgaaaccca agaggaaatc cggggaaacc
     8641 ttaccgatca caccctcact accgatctga ggcaagccat cttcgtctac gacaatgtca
     8701 ccgttgtcat tacgcaagaa agtcgtacca tagattacag ggaatttatc gccaatattc
     8761 gcacgtacct gcggatcaac gaaacctccc aagaaaatac tctctacacc cggagccagc
     8821 tcatccacgt agttatcgat cttagagaag ttaaatgcca tatcccattt aaaattcttc
     8881 gtattgatcg gattgattcc caacgtaatc tcatgagcgt tcgtatggat agcgccacca
     8941 ttggttacta attctgcaga gcctgtagaa ccagccaaag gaacctcaaa tatctgatct
     9001 ttcacattct gccgagagaa ggtatagttc aatgagaaca gaccattcaa gaaggtcaaa
     9061 tccacaccta actcataaga cttcgtgttc tgaggtttca gattcggatc atacacacga
     9121 gcatatggag tgaacgccgt aattccactc ataggatatt gtataggcgt agaaccataa
     9181 aaaccaccac cgtaaacagg tgtagtataa taagaatcat aataatctcc agcctgtcct
     9241 acttcggcgt aagaagcacg taatttacca taagtcaaga cattattctt caatggttct
     9301 aattctgtga aaatccagcc caaggaaaca gatggataag tgaatgagcg gttgttacga
     9361 ggcatattag atacgatatc gttacgaaca gttgcgttga agtaaaccat gttagcgtaa
     9421 gacaatgaaa tgctagcaaa gttaccaact gtgcgtttcc ggcgtaatga ctcggatgct
     9481 accatagttg tagcattatc tatatgattc caacccggga agttatagtt cgctccataa
     9541 gactcgtaaa atttccgctg attctctacc aattcattac caacaagggc atcgaacaac
     9601 caatcttcat tgatattcca agtatatgca gcggtcaaca aagagttcaa ctccgtgatt
     9661 gaatatccat agtgatcaat ctctccataa ccatttgcat gtccataacc ccaagaatcc
     9721 gtataattag tcgtataaga gtccacaccc aattgatact tgacatccaa tttgtgatta
     9781 tcggtattga acttcgtaga atatttcaaa taagtatttc caaagaaacg ttgtgaacgt
     9841 tccaagaact cgttgttatc taccgcccaa taagctccgt caaaacctga tgtgctacgg
     9901 aatgtatttt gtgtatacgg gtcaccctca acatgacttg ggataccggc taaatcgtag
     9961 ctagaaggag ctccgtaaac agtagctaag attccattat tggcactaga ctgcttgctg
    10021 atcttcgaat ttacataggt accggtaaat ccagtagacc agttcttgtg taattgagct
    10081 tcggcactca tttttgcgtt gtatcggtcc atgcctgtat ttggaataat accatcttgc
    10141 gtagtattac cgatcgagaa ggaatagtta cctttatcaa aagcttgagc tacattcacg
    10201 gagttactcc atgtcgtacc cacgttgaag aaatccttga tattgtcgta agcttgtggt
    10261 tgagcccaag ggtctaatcc cgcagcggcc cgctgaggta cataatacat accttcatgc
    10321 ttaccatatt gcttggtaaa ctcattatcc gtatttcctc cataagtcgg atcgttaggc
    10381 aattcgctga ttagtggtcc ccaagaagtt gaagcatacg ggctatactt gccatttgta
    10441 ccctgcgcat acactttttg gtattcaggc atcgttgaaa ccttatcaaa agataagctg
    10501 gtattaaaag cgacctgagg tttaccttta cgggctccct ttccactttt ggtcgtaatg
    10561 acaattactc catttgttgc acgcatacca tacaaggcag atgcggcctg tccctttaat
    10621 atattaatgc tttcaatatc gtttgggtcg atatccaccg cacgagatgc aaagtccgtg
    10681 ccggaaacag aactaccggt gtccacatca gccgttgaag cgacaggcat accgtcaatc
    10741 acatacaaag gagtattatc ccctgtaaaa gatctggaac cacgaatcgt gatcttagaa
    10801 gaggcacccg gcataccgga agaaggagag atctccactc cagaaacctt accttgtaat
    10861 gcgccagaca aactagtatt agctcctttc gtcaactcat ccgctttcac atcttgaacc
    10921 gcataaccta aagctttctt ttcctttgag atacccatag ccgtaaccac gacctcatcc
    10981 aagttctggg tatcggctaa tagttttaca tttacattag aagtggccgc aacttcttga
    11041 gatttcatac cgatgtatga aataaccaat tgtttaccat tcgcaggtac ttctagttca
    11101 aagtttccat caaaatccgt gactgttccc acggttgtcc cttttacgat aatagaggca
    11161 ccgatcaccg gctctccatc ttccccaatt accttaccgg taaccttcga ggtctgtgct
    11221 gaaaccacac ctgcactcaa tgcaagaaat agtagcacag aagtcaactt tttcttcata
    11281 aacacactta tttattaact atatacttaa aaatgttttc tctgcatttt aatggttgat
    11341 taactaagtt catacagaac tactccattt tatgttttac gacataccta ttaaatgaaa
    11401 aacggttgca aaactataaa ttatacctga aaaaaacaac aaattattat tattgtgata
    11461 tatttccttt gttttcttaa ttgttaaatc tgtcaatttg caatataacc actgtctaaa
    11521 tcgactcagg tgacatgatc gtatcacaaa tcaatgagtt atcgctgccg atagtttctt
    11581 tttgacaaat aaaaaaatta tttttatctt aattttatcg taacaaatag tgagcttact
    11641 ctttataggc atgatattgg acttgatatc aacttattct ggatatttta tagcatatag
    11701 cttatcacta aaaatattta caactttatt ttatgtagat atttgtgaaa aacggctggc
    11761 ttttcttatc ctcccaatat ggctgataaa caatatctct caaatccaat atatttatta
    11821 cagaatttta atagatctaa acttatatga taattttttt tcatatgact acactaaata
    11881 aaatattgaa aattggtagt tctgtatgaa ctatagtcca cgaaagctta attgaatttc
    11941 tagtttagtt taaataaaaa gaatgtgtct atgaagaaaa agttgacttc tgtgctacta
    12001 tttcttgcga tgagcgtagg agtagtttcg gcacagacct cgaaggttac cggtaaggta
    12061 gtcggagaag atggtgagcc ggtgatcggt gcgtccatta tcgtaaaagg aacgactgtg
    12121 ggaacagtta cggattttga cggtaatttt actttggatg ttcctagtga tggtaagcaa
    12181 ttagttattt catacatcgg tatgaaatcc aaggaggtag ttgtgtctcc caatgtaaat
    12241 gtaacattga tgtctgatac ccaaaacttg gatgaggtcg tggttacagc gatgggtatc
    12301 tcaaaggaaa agaaagcttt aggttatgcc gtgcaagatg taaaatcgga tgagttaaca
    12361 caaggtgcta acactagttt gtctggggct ttgcaaggta aagtatccgg tatcgatatc
    12421 gcttcctcat cgggtatgcc aggcgcatct tccaagatca tgatccgtgg agcccgttca
    12481 tttacagggg ataactctcc tttgtatgtg atcgatggta tgccgatcgc ttctacggcg
    12541 gatgttaata cggatactat gaataatggt agtgttagtg gagctgacta tgcgaaccgt
    12601 gccgtagact tagatccgaa cgatatcgag agtatcaaca tcttgaaagg acaagccgct
    12661 tctgcgttgt atggtatgcg tgcttctaat ggtgtgatcg ttattactac aaagagcgga
    12721 aaaggtgctc gtaaaggaaa acctcagatc tcattcaaca cgaatcttgc gtttgataag
    12781 gtttctacat tacctgagtt acaaactgaa tatggacaag gtaatgaagg tgcttataac
    12841 ccatattcgg gatttagctg gggaccgtct atctctgact tggcgaatga tcctgtatat
    12901 ggcggtaatg tacaaaatga atatacggaa ggtggattgc ataatggaca atactatgtg
    12961 cctcagcgtg ctgcggcagg attggatcca tgggctactc cccaagctta taataatgcg
    13021 aaagatttct tccagactgg cgttacttgg agtaactctg taaatgtagc tcaatctttc
    13081 gataaaggaa actattcatt ttctttgggt aatacgactt ctgatggtat cgttcgttct
    13141 acgggaatgg atcgttataa cgtgaagctg tcgggtgagg cgcaattgca tgataactgg
    13201 acgactggtt ttaacggaaa cttcgtgaca tcaaagatca agaagcaagg aaccgctaat
    13261 gacggtgtta ccgctacggt ttatacggct cctatcagtt atactatggc gggcatacct
    13321 tcccatatcg aaggtgatcc ttatactcag aatacgttcc gtgagaactg gatcgatgat
    13381 ggaaactggg cgtgcgacaa taatagcttt acggagagat ctcaacgttt cttcgggaat
    13441 gcgttcttga agtattctac taaatttggt acggacaatc ataaattgga tgtgaaatac
    13501 caaattggtg atgacgctta tacgaccaat tactctgata tttacggcta cggtacaact
    13561 ggttatgcga atggttatgc tagcgaatac ggttttacgg taaatgagat gaactcattg
    13621 ttgacgttta cgtataactg gaatatcaat gaggacttcg tattcgatgc tttgttgggt
    13681 aatgagcttg tagataagcg aatcagtaat actcaagccg tgggatatag cttcaacttc
    13741 ccgggctgga accatttgaa caacgcttct gtattcaaca gctctcatga gtataagaga
    13801 aaacgtacgg taggtaactt cgctagctta tctttggctt ggaagaatat gctttatttg
    13861 aatgttacgg gacgtaacga tatcgtgtct tctatgccga gagataaccg ttcgttcttt
    13921 tatccttccg tatcccttgg atgggtattc acggaagtgg aagccttgaa gaatgatatc
    13981 ttgacatttg gtaagatccg tggctcttac gcagaggtag gtatggcagg agaatatgtg
    14041 ccgtcttatt attatacgcc aagttatggt ggtggtttct tccagggaac acctattatg
    14101 tatccgatta atggaaatat ggcgtatatt ccttatttcg tggtttatga tccgaacttg
    14161 aagcctcaga acacgaagtc ttatgagctt ggtgctgact tgactttctt gaatggttta
    14221 gtttcattga attatacgta ttctcgtcag aacgtgaaag accaaatctt cgaggtgcct
    14281 ttggctggct ccacaggtgc ttccagtatg atgatgaatg gtggaaagat gcactcaaac
    14341 gtacatgaga ttacattagg tatctctccg gttgatacga agaatttcaa gctggacttc
    14401 gcttttaact tctcaaagat cgacaattat gtagacgagt tggctccggg cgtagagagc
    14461 attatgttgg gtggtttcgt gactcctcaa gtacgtgcag gtatcggcga taaattcccg
    14521 gtaatctatg gtgttggtta caaacgtgat ggcgaaggac gaattgtagt aaacgaaaaa
    14581 ggtataccag aggctggtga gacccaagta atcggtaagg tttctcctga tttccgtttg
    14641 ggtttcaata cgaatatcga gttgtataaa ttccgtttgg ctgctgtatt tgactggaag
    14701 caaggtggac aaatgtatag tggtacggct ggtgagacta acttctacgg tacaagtaag
    14761 ttatctggag aggttcgtaa gagtgataaa tatcattttg actatgctgc tgttgaacag
    14821 aagggcgtag atgcggatgg taaacctatc tatgttccct atacgggtgg agtgaaagga
    14881 tcagatgcag aggagtattt caaaagcgtg aggggcattg acgaagccta tgtctatgac
    14941 aactcgttct tgaaattgcg tgaactttca ttgtcatatc ctgtatataa gaaagataac
    15001 ttgaatgtaa acgtgaatgt tttcgcccgt aatatcattg tatggtctga gataaaaggc
    15061 ttcgatccgg aggctactca aggaaataac aatatggctg gcgctttcga gcgtttctcc
    15121 ttaccgggta catctagcta cggttttggt gtcaacgtaa atttctaatt tataaagaag
    15181 acagatatat atgaatacaa taataaaatc atttaaaggg ttggctgtta tgtcggccgt
    15241 atccttggca ttggctggat gttccgagga tgtaatggat cgaattaacc aagatacgag
    15301 ccatacaaat agcgtggatg gcaaatttat cttggccgac ttgattactt ctactgcatt
    15361 ttccaacgtt agcggagact tcaataccta ttcatcttcc tacgtggaat atgaagtggg
    15421 tatcgaaaac cagttatata acgcggaaat tcgtttgaat gagccttctg cctcttctac
    15481 gtttgagaat acgtggggaa atgtttatac aagcttgaag aacgctcgtg ttattatcgg
    15541 tcaatgtcaa gaaggtaagc gtgatgaggg aaatttagtg acgagaggta tcgctgaggt
    15601 catggaagct tacaatggcg ctctattggc ggatatattt ggagatacac cttatagtga
    15661 agcttcttta ttggatgaga atggctcacc ggtgaatatg aatcctaaaa tagataagca
    15721 agaggagatt tatgtctcta taatggcctc cttggacaag gcgatcgagg atttgaatca
    15781 gtctgatcgt tcaccggttg gtacgtatga ttatttgtat aatggagatg ccgagaaatg
    15841 gattaaattc gcttatggtt tgaaggctcg ttatacgatg cgtctgatca atcgttccac
    15901 ggataagcaa gctgatttga ataaggtttt ggactatgta tcaaaatctt ttacttctgc
    15961 ggatgacgag gctgcatacg ctgtctatga tgcgaataat atcaacccat tctttggtta
    16021 cttcgattct cgcgctggtt ttgccaatag ccagagcttg acggacaagt tgattgagcg
    16081 taaagatcct cgattggaaa gagtgatgct ttctcctact acggctgaca agaaacgcgt
    16141 acaggttaca ggctctgctg ataagaactt agttccggcc ccgaatggta ctcctgagca
    16201 gaatatgcag aaatatggtg tttccgcctt tgtatattca aacacggctc ctacgatgtt
    16261 gatgagttat catgagttga aattcttgca agctgaggcg ttatgtcgct taaaccgtac
    16321 gtctgacgcc gagaaagcgt tgaaagaggc ggtagctgcc ggaatcgcaa atgctgaaag
    16381 aagtgtctct tctgctatca cttatatggg tagcaaaatg gtcgtgaatt cagaaaaaat
    16441 gacagaggag acggccaata catatttcga gaaccaagtt aaaccgctgt ttgctgtaaa
    16501 tcctttgaaa gagaccatga tccagaaata tctggctttg tggggggcat cgggagaggc
    16561 taccgagact tttaatgata tccgtagaat gaaaggatta ggagagaatt tcgtgacatt
    16621 ggcgaatacg aaaaaattcc ctcttcgtat gccttatggt aatagtgacg tggtatcaaa
    16681 tccggaagta aaagccgctt atggcgacgg tcaatacgta tattcagagc ctgtatggtg
    16741 ggctggcgga actcgctaat ctaacatata taatataatg tatagggtgc ctctccgatt
    16801 atggaggggc atcttttttt gttatatatc ttacatgttt tgatagcttc ccttatccca
    16861 tttccttgga aggcttattg gttttatatg gaaatataga tcatctaaca attggtgcat
    16921 gatcatctaa caatcgttgc atgatcatgc accaactgtt ggacgatcat gcaccagctg
    16981 atagatattt aatgcttcaa gaaaaaaggt ataatgtgtt aagaagatat cgctaaaagt
    17041 acgggataaa aaggataggg aactaaggga atgttaaatt tttattgtca taatgttagt
    17101 atattatatg ggtaaaagtg tgtttgtgat gattactctt tcattatgtt actatttcct
    17161 gttgtttaac attcttttta tacgataaat ttcttgactt atcctttgaa aagtaaataa
    17221 aatgtccgac ttttgcttcc atgatgagtc aaccattagc agagagatta cgtccgaaga
    17281 cgttggatga ttatatcgga cagaagcacc tggtaggcca gggagccgtg ttgaggaaga
    17341 tgattgatgc gggacgggtt ccctctttta tattgtgggg gccgccggga gtagggaaga
    17401 ctaccttagc gcaaatcata gcgaataagt tggatgcgcc tttttatacg ttaagcgcaa
    17461 tcagttcggg agtgaaggac gtgcgggagg tgatagagaa ggccaagagc aaccgcttct
    17521 tcaatacggt atcgccgata ttgtttattg atgagataca ccggttcagt aagtcgcagc
    17581 aagactcatt gctgaacgcc gtggagacgg gcgtggtgac gctgattggg gcaaccacgg
    17641 agaatccctc gttcgaggta atccgtcctt tgttatcccg ttgtcaggtg tacgtgttga
    17701 aatcgctgga caagaatgac ttgcttacgc tattgcataa ggcgatcgcc gaggatgtcg
    17761 ttctgaagga taaaaacata aggctgacgg aaacggatgc catgttacgt tactcgggag
    17821 gagatgcccg gaagttgctg aatattctgg aactggtggt gtctgccgag gagagtgacg
    17881 atattgagat tctggatgag aaggtagtgg agaggttgca ggagaaccct gcggcgtatg
    17941 ataagggagg ggagatgcat tacgatataa tctccgcttt tatcaagtcg atccggggta
    18001 gcgatcccga tggcgccatt tactggctcg cccgtatggt ggccggggga gaagaccctg
    18061 agtttatcgc acggcggttg gtgatctccg cttctgagga tatcggattg gcgaatccga
    18121 atgcgctttt gctggcgaac gcatgtttcg atgccttgaa gaagatcggc tggccggagg
    18181 gccggatcat cctggccgag acgaccgttt atctggcttg cagcccgaaa agtaattcgg
    18241 cctatatggc gatcaacgac gctttggcac ttgttaaccg gactgggaat ttacccgtac
    18301 cgcttcatct acgcaacgcg cctaccaaat taatggctga attggagtat ggcaaggaat
    18361 ataaatatgc gcacgactac gaaaatcatt ttgtaaagca ggagtatctt ccgaaggaaa
    18421 ttttgggcga acgtttgtgg aaaggacagg aaaatccggc cgagcacaaa ctaattgagc
    18481 aaatgaggcg cctttgggga gatcgttttt aattgacata ttctgattgt aaattaaaaa
    18541 atgctcgaaa agtgtcggca aatgagaaaa aatagttaca ttagccgcct atttttgaaa
    18601 aaatagttac tttatttata ataacattct aaaaagacat tggtatgaag aagcacaatt
    18661 tttatgcagg tccttctatc ttgagcgagt atacaattaa gaatacagcc gctgcggtag
    18721 aaaattttgc gggtatgggg ttatcacttc ttgagatctc tcatagaagt aaggagtttg
    18781 tagccgtaaa cgacgaggca cgtgcgttga tcaaggaatt actggatgtt ccggcaggct
    18841 atgaggttgt attcatgggc ggtggcgcca gcatgcagtt ctgtatggtt ccttacaatc
    18901 tgttgaataa gaaagcctct tatttggata ccggcacatg ggcttcgaac gctatcaagg
    18961 aagctaagtt gtttggggag gtagatgttg tcgcttcttc caaagacaag aactatactt
    19021 acatcccgaa gggttatgcg atcgctgatg actcggatta tttccatttt acttctaata
    19081 atacgattta cggaacagag atgcgtaagg atccggatgt gaagcaacgt ttggtttgcg
    19141 atatgtcttc cgatattttc tctcgtccga tcgatatttc caaatatgat attatctatg
    19201 cgggtgctca aaagaacttg gctcctgccg gcgtgacttt ggctatcgtt cgtgtggacg
    19261 ctttaggaca tgtagaccgt ccgatcccga ccatgttgaa ctacgctacc catattaaaa
    19321 aggattccat gttcaataca cctcctgtat tgcctattta cgcggcttta cagaccttga
    19381 aatggtataa ggaacaaggt ggtatcgccg ctatggagaa gaaggatctt gagaacgcgg
    19441 cgatcttata cgatgagatc gatcgcaata agttgttccg tggtacggta gcggaggaag
    19501 atcgttcgat catgaatgtt tgtttcgtga tgaatgatga gtataaggag ttggaggacg
    19561 agttcagtaa atatgctact gccgctggta tggtaggtat caagggacac cgttctgtag
    19621 gtggtttccg tgcctctctt tataacgcga tgccgaagag cagcgtggag gctttggtag
    19681 cttgcatgaa agagttcgag aaacaacatt aatcaaggag gattcagaca tggcaaagat
    19741 attagttgct acagagaaac ctttcgccgc tgtcgctgtg aaaggtatcc gggaggtagt
    19801 ggaaggcgct ggtatggaac tggctctttt ggagaaatat acagagaagg cgcaattgct
    19861 ggatgcggtt aaggatgccg atgccgtgat tatccgtagc gataaggtgg acgctgaggt
    19921 attggatgcc gctaagaacc tgaagatcgt ggttcgtgcc ggtgcggggt atgataacgt
    19981 ggacttggat gcggctactg cccataaggt atgcgtgatg aatacgccgg gacaaaactc
    20041 taacgctgtc gccgaattgg tattcggtat gttggtgtac ggggttcgta atttctataa
    20101 cggaacttcc ggaacagagt tgaaaggaaa gaaattgggt atcttggctt atggaaacgt
    20161 gggccgtaac gtggctcgta tcgctaaagg cttcggtatg gaggtttacg cttatgacgc
    20221 gttctgtccg gcttccgtga ttgaggccga tggtgtgaag gctgtagctt ctacggcgga
    20281 cttgttcaag gcttgccaga tcgtttcctt gcatatcccg gctacggccg agacgaaggg
    20341 ttctatcaat ttcgagttga tgaattccat gccgaaggga gctatcgtag tgaatacggc
    20401 tcgtaaggag gtgatggatg aggctggcct cgctaagatg ttggaagagc gtccggattt
    20461 caagtacttg acagatatta tgcccgctat ccatgcggaa ttggccgaaa aatatgccgg
    20521 tcgttatttc agcaccccga aaaagatggg tgcccagacc gccgaggcta atatcaacgc
    20581 tggtatcgcc gccgccaagc agatcgttga tttcttggtg aatggcaatg aaaagtatcg
    20641 ggttaataaa tgagaatatc cggttgtaga gacgggtacg ccccgtctct acattgatac
    20701 ataaaccaat tagatttaat taccatggca aaaataaaac ctttcaaggg agttcgtcca
    20761 ccaaaagaat ttatagagga ggtggcttcc cgcccctatg acgtattgaa ctcgcaagaa
    20821 gctcgtgcgg aagcggaagg aaacgagaaa tccctttacc atatcattaa accggaaatc
    20881 gatttcccag aagggacgga tgagcatgat ccggctgttt acctgaaggc cgccgccaat
    20941 ttcaataatt ttcaggaaaa aggttggttg gttcaggatc agaaagaatg ctattatgtt
    21001 tatgcccaaa ccatgaatgg caagactcaa tatgggttgg tagtcggggc ttatgttccc
    21061 gattatatga atggcacgat caagaaacat gagctgaccc gccgtgacaa ggaggaggat
    21121 cgcatgaagc acgtacgtgt caacaacgct aatatcgagc cggtattctt cgcttatccc
    21181 gacaactcag agttagacgc tatcgtaatg aaatatacgg ctcgtgagcc tgaatataat
    21241 ttcgtggcga aattagacgg tttcggccat acgttctgga ttatcgatga ggataaggac
    21301 atcgcccgca tcacggagtt attcggggag atgcctgcgt tgtatattgc cgacggacat
    21361 catcgttccg ccgccgctgc tttggtagga gcggagaagg ccaagcaaaa cccggatcat
    21421 aagggagacg aggagtataa ctatttcatg gctgtttgct tcccggccaa ccaattgacc
    21481 attatcgatt acaaccgtgt ggtaaaagac ttgaacggct tgaccgagga acaattcgtt
    21541 gagagattaa cgaaaaactt cgtggtagag gagaagggct ctgctattta caaaccgggt
    21601 gccttgcaca atttctccct gtatttagga gggaaatggt attctttgac cgctaagccc
    21661 ggtacgtacg atgacaatga cccgataggc gtattggatg tcacgatctc ttcgaacttg
    21721 attctggatg agattttagg cattaaggat ttacgttcgg acaagcgaat cgatttcgtg
    21781 ggaggtatcc gtggcctggg tgaattgaaa cgccgtgtgg atagcggtga gatgaaggtt
    21841 gccttggctt tgtatcccgt tacgatgaag caattgatgg atatcgccga tacgggtaat
    21901 attatgccgc cgaagacgac gtggttcgaa ccgaagcttc gctccggttt ggtgatccat
    21961 aaattggatt aagtcttata tacataaata tagctttgga ttggggtata atcgttgaag
    22021 attataccct tttttatcct tgtaacctag atatacggaa taaattgtat ctttaggact
    22081 taaatagtat cgcaatgggt aaaataaaaa atatagtatt cgatctgggg gcgttatcat
    22141 agatttggac cgggatgaac ctgttcgtcg tttaatagag attggggtca aagatgccga
    22201 tggattgata gatccttacg aacaaaaagg ggtttttcaa gatctggaga ccggaaagat
    22261 cggagtagag gagttttgtc gctatttacg gaagcatacg ggtaaagacc ttttttatga
    22321 ggatatttgt tgggcttggt ttggcttcat tggtggcgtt ccccaatata aattggacta
    22381 catattaaaa ctccgtgaga aatatcaagt ctatttattg agcaatacaa atccgatcat
    22441 acagcttgaa tgggcacaga caaaagagtt tacgccggcg ggccgtccat taaatgatta
    22501 tttcgataaa ttgtatctct cttatgaaat cggtgtcacg aagccagatc gtgaaatttt
    22561 tgatcgcatg gtcttggatt caggaatcag accagaggaa acattatttg tagatgatgg
    22621 taagaataat atcgtagtgg ggcaggaact ggggttccat acctatcagc ctttgaatgg
    22681 agaggattgg agagggaggc tcgatgaaat actctcaaaa tcataggatc tctattcctc
    22741 ttaattaaat ctatatcatt gaaaatgaca aatactactt taaatttgga agaactactc
    22801 tgtggtgtaa acgagctagt cgatacgctt tggatcgtca cattaggtaa tgaaaaggtt
    22861 gagatagtca aagattcgat gactcccgaa agggaaggag aatgtttgga ttatacagaa
    22921 ctttgccaga cttacattca agaatatgta tatcctgcgg atttagggaa atgggaggag
    22981 atcttatcct tgaattcatt gcggcaaatg gcggctagcg gcgtagcaaa taagaagttc
    23041 gacatgcgtt tctgtaatga tttgttgggt tttgagtggc atgaggcttt tattcgtatc
    23101 ttgaaagata agagtggaat tccggatcgt gtcattcttt tcagccgcta tgtgaatcat
    23161 tgtcgcaagg cacagatcgt agaggctgcc gttcagactg agtatgatta tgtcgtttat
    23221 atagaggcaa atacgaatag ctatgtcatg tatacttcca atcgtgaaag tgggatgccg
    23281 gtccccccga tagcgagtaa tgactatgaa aaagaggtag ccgagttcca ccacaaatat
    23341 gtgccggagg atcagcgaga tgagttaacc cgaaatcttt ccctagatca tgtcttatct
    23401 atcttacaaa attcccgtga gtatgtcttg ttctgtcagg tgatggagaa tggcgttttt
    23461 agggataaga agttgcgttt tagctttttc gataaggaga ggaatatact tcttttgacc
    23521 cggaccgata ttatggaggt tcgtgaggaa gagcggcaaa ggcaattact tcaagatgcc
    23581 ctacaagtgg ctaaatcggc aaatcaggct aaatcagatt tcttatcccg tatgagccat
    23641 gatatacgta ctccgatgaa tgccattatc ggtatgacca ctatcgccag tatgcatatc
    23701 gacgatcggg agcgtatagt ggattgcttg aagaagatta tggtttcttc caaattgtta
    23761 ttgaacttga tcaatgaggt cttggatatg tctaaggtag agagcggaca tattttgctg
    23821 acagacgagg agttcgatat gggcgagtta ttgcaaagcg taattactat ggttcagact
    23881 tcggtcagtc agaagtttca ggatttccgg gttcacttgt ttcaaatcaa acatgaaaag
    23941 ctgattggcg atgtgcaacg gattcagcaa gtattgttga atttgctgtc aaacgccata
    24001 aagtatacgc cggactatgg gaaaataaca cttgagatac gggaaaagcc aattaaaaat
    24061 ggtaattatg gtttatttga ggttacggtt atagacaatg gtatcgggat aaagccggat
    24121 ttcttacaca aggttttcga accatttgaa cgtgcggaag acgcaacctt gcggaatata
    24181 caaggaaccg gcttaggcat ggcgataagc cgtaatatcg ctcatatgat gaatggtgag
    24241 attctggtgg agagtgaata tggcaaaggt tccgttttta catttacgat gcagttgaaa
    24301 ttgcaggatc aagggtgttt tgaggatgat catttaaggg atttaccggt tctcgtggta
    24361 gacgatgata tcgtgtgttg cgagaacgca tgtatgagga ttaacgagat cggtatgaaa
    24421 ggtgaatatg ccatttctgg tgaggaggct atcgggaaag tagagagggc acatcatctt
    24481 aatgatgact attttgccgt tatccttgat ctgaaaatgc cgggaatgga tggaatcgag
    24541 accgctaccc gtatccgaaa agtcgttggc cgggatattc cgatcattat tctttccgct
    24601 tatgattgtc cgcattttga ggaaatagcc caacgagccg gtgtcgatgg attcataagt
    24661 aagccgttga tgaaatccaa gttattttat ttgatgaaaa gtttcgctat caagcaagag
    24721 gaaaaagagg aagagacgga gaagcctcaa tatcctttcg gtaactttga gggtaagcgg
    24781 atcttgctgg tggaagataa tagcttgaat agggaaatag cgactgtgtt actagaagag
    24841 accggtgcgg tggtagagga ggcggaaaat ggccttgtcg cggtgaatat ggtaaaaaac
    24901 tctagtccgg gatattatga cttggtattt gtggatatcc agatgccggt catgaacggg
    24961 tacgactcta ctcgccatat tcgggcatta gaacgtccgg atatcaagtc catgccgata
    25021 atagccatgt ctgcgaacgc atttgcggaa gacatcaagt tgtgtaaaga atccggaatg
    25081 aatgagcata tcgctaagcc gatcgatttc gggaaggttc ttgagatctt agagaagtac
    25141 ttgtagatat aaggatataa aaaaggccat atcttagcta agcgctatca gatacggcct
    25201 cttttttgtg ttatttactg gatgccacgt tctctcaaac gtttctgcca gttccatgcg
    25261 gattgcaggg tgtcggctaa agtctccttg gcggtccagc ctaatacctt attcgcgtgc
    25321 tccggattgg cccatacctt ctcgatatca ccttcacgac ggcccacgat cttgtgcgga
    25381 accttaacgc ctgttgtctg ctcgaaggta ttgatcagtt caaggacaga aacaccatta
    25441 ccggtaccta ggttgaatat ctcgatatgc tcatcagact tattctcaag catacggtcc
    25501 atagcgatta catgcgcttt cgccaagtct acgacattga tatagtcacg gatgcaagag
    25561 ccgtctgccg tatcataatc atcgccgaat acgcttaatt ccttgcggat acccatagcc
    25621 gtctgtgtca agtacgggat caagttctgg ggaacaccat tcggcaactc gccgatctct
    25681 gcgcttgggt gagcgcctat cgggttgaag tagcgcaaga tgatactctt gaaaggcgct
    25741 cccgcatgga tcgtatcccg gataatctcc tcgttgatct gcttcgtgtt tccataagga
    25801 gacatagcgg gtttgatcgg ggcattctcg gttaccggca agttctccgg atccggttgt
    25861 ccgtataccg tacaagagga agagaatacg ataccttcga tattgaattc aggcatcatc
    25921 tccaacaagt tcaccaaagt gacaatatta ttgcgataat acttcaaagg ctgctgtacg
    25981 gattctccta ccgccttgct agcggcgaac aagataatgc ctttgatgcc cggatgagct
    26041 tccaatgcct tgcgagtacc ttccttatcc tttagatcca attggataaa ctccggacgg
    26101 atgcccgtga ttttctcgat accatcgagc acctcgatat tcgagtttga caaatcgtcg
    26161 ataatgacta cctcatatcc ggcgttctgc aattctactg tggtgtgtga gccgatataa
    26221 ccggttccgc ccgctactaa aatcttcttt ttcattctag tgttcattta gataagtttg
    26281 ttatacgata cccgagaatc ccataaaagc catagctagc aaaccggccg ttatcaaggc
    26341 gataggagtg cctttcatgc cttccggaac atgcgtcatg gctagttgct cccgaatacc
    26401 cgcgaagata atcaaagcta gcgcaaatcc aatagcggtc gagatagcat ataccacaga
    26461 ttctaataaa ttatactctt tttggattac aaggatcgcc acacccaaga tacagcagtt
    26521 cgtggtgatc aacggaagga atacgcccaa cgcctggtaa agggcgggag agaccttctt
    26581 caatatgatt tccaccatct gaaccaaggc ggcgatgatc aagatgaaac tgatcgtctg
    26641 catgaaccct aatccgaaag cgtccaatat gtatttttgc acgaggaatg taacaatcgt
    26701 ggcgatcgta agcacgaacg taacggcggc tcccatgcct gcggcagtct ccactttctt
    26761 agataccccc aagaacggac aaattcccaa gaactgtgcc agtacaacgt tattaacgaa
    26821 tacggcggcg ataaatatca atatatattc catatgatcc gtttattatg ctttacgcag
    26881 tttgtttact attgctacca gataacccaa ggcgataaac gctcccggag ccaatacgaa
    26941 gatcagcgaa ccatattcct cgggcatcaa ggttacgttg aataacttac cggttcccaa
    27001 gaactcacgg caagcgccca gcagcgtaag agccatcgta aagcccagtc cgataccgat
    27061 tccgtcgaaa gcggatggga ttacgccgtt cttcgcagcg aaagcctcgg cacgtcctag
    27121 tacgatacag tttaccacga tcaacgggat aaataatccc aagctagcgt ataaagccgg
    27181 gacgaacgct tccatgcaca tctgcactac ggtcacgaac gtcgcgatca caacgatata
    27241 tcccgggata cgcaccaagt cggggattac gtttttcaag gcggaaatca cgatattcga
    27301 gcaaatcaat acgaacatcg tagccaatcc catactcatg ccgttgatgg ccgaagaggt
    27361 cgttcccaag gtaggacaca tacctaacag taatacaaat gtcgggttct ccgtgatgat
    27421 accattcatc aatattttta gattactcat tgttctgtcc tcccttttta tttgttatca
    27481 gttgaagtgg cacccgttag tccgtctacg ccagcgaatg cgctatacgc acggttcacg
    27541 gcatcgagga acgcacggct ggagattgtc gctgccgtga tagcgtccac atcgccacca
    27601 tcttttgtta cttttaagcc tccgtccgga atcgtacgtc ccaagacact ttgcttgttc
    27661 ttgtccgcac ggaaccattc ttgcatcttg gctcccaagc ccggagtctc ggcgtgttgc
    27721 aatacggaat agttcaagat cttgccatcc atatcgaaac ctacgataac ccgtatctca
    27781 ccgctaaagc cttttttcgt attactctct acagctccgc caacgacttg tccgcctttc
    27841 ttggcaggat aaatcttgag ggaatcacca tcggaggaga cggccatata gacgtcctca
    27901 gtcggtttgt tgtcgaactc gggagcaacg gctttaatcg cttcctccaa ggcggtcgct
    27961 ttggctaccg ctatagggcc ggcggtaaac tggttcactc cggctaggat cgcccctgct
    28021 accaagcaaa tgcctgttag tgaaaggagc atattgggta atgttgattt taattttgcc
    28081 atgcttactt tcctccgaaa tgtttaggtt tgatatagct gttgattagc ggagtaaatg
    28141 cgttcatgat caggatagcg aacgacatac cttccgggta agacccgaac aaacggatca
    28201 ccgtggtaag gattccgatt cccacgccgt agacaagcat tccgttcttg ctcatcggcg
    28261 aggttacgta gtcggtcgcc ataaagatgg agcctaataa caaaccaccg gataataaat
    28321 gaacgaacgg gctggcgtat tgtaccggat tcaccaagtg catgatgccc gtgaatacga
    28381 atacggtagc caagatggat accgggatct gccaagtgat gatctttttc catagcatga
    28441 ataaaagacc gaggatcaag gccagggcgc tcacttcacc gagactacct cccatagccc
    28501 ctacaagcat attcccgtaa gacggaagct cggtcacgcc ctcgttcatc aacgacagta
    28561 ccgtcgcgcc ggtctgggcg tccgtataag tcatcgggaa aacgttcaag gcatctacca
    28621 ccggccaagt cgtcatctgc gccgggaagg agatcaataa gaatacacgt ccgaccaacg
    28681 ccggattgaa aatattatta cctaatccac cgaaagacat cttgccgatg ccgatcgccg
    28741 ccaacgctcc gatgataatg atccagaccg gaaggttgga aggtaggttg aaggccagca
    28801 atacgcccgt caggatagcg gagccatcgc aaagggtcgg ttcctttttc atcaggaatc
    28861 gctggatcaa atactcgaat atcatacagg ccagaaccga tacgaccgta acgatcaacg
    28921 ctcccagacc gaagaaataa agggatacca agaaagccgg gataagggca atcagtacac
    28981 catacatatt tttgcttatg ctgtcgcctc catggatgtg gggcgagggc gatacgtata
    29041 aattattttc catgttgctc ttgttttatg actttctaga ccggataata cccataactt
    29101 ttcctttacc caaccggatc tgatccagca acggacggtt ggccggacag gtataactac
    29161 acgacccgca ctcgatacag tcggtgatat agttcttctc cgccaattcc caattctgga
    29221 attccgtggc gttcatcaat agggtagggt tcaatcccat cgggcagaca cctacgcatt
    29281 tggcgcaacg gatgcaatcc cggatcggct tgcggacaga ttcctccgtt gtcagtaata
    29341 aaacaccgga gcttcctttg caaactggca cctcggcgct gatcaacgct ttacccatca
    29401 tcggtccgcc accgataatc ttacccgtat tctcgggcag gccacctgcg gcctcgatca
    29461 agcaactgat cggtgttccc atacgaacca agaaattgga aggattagct accgccttac
    29521 ccgtgatcgt caccacacgc tcgaacaacg gtttattctt ttgtaccgcc tcgtaaacgg
    29581 cataagcagt tcctacgttc tgtaccacgg cacccgccga gataggaagc gcaccacttt
    29641 ttacctgacg gcgaataacg gcgtcgatca attgtttctc gcctccttgc ggatattgta
    29701 ccttaagcgg catgatctct atacctttat aatttaccgc caacttttgc agatgggcga
    29761 tagcgtccgg cttgttattc tcgataccga tcacggcctt gttcacgttg accgctttca
    29821 ttaggatcgt gacaccgact aggatttgct cgcctttctc cagcatcaac gaatggtcgg
    29881 aagtaagata aggctcacac tccacggcgt tgatgattac gatctctgcc ttgtttccgg
    29941 gaggcggcat caatttcacc tgcgtaggga aagtcgctcc acccagaccg acgataccgg
    30001 aagcggcgat cttatccacg atttccttgg aagacagcgt gcactccttc actaaggtct
    30061 cgctgcggtc gatcgtctct tcccattcat caccttccac atctatatag atagcgggac
    30121 gtttgtatcc gctagcgtcg agagcgttat ctatcttgtt cactttgccg gatacggaag
    30181 agtggatgtt cgctgatacg aaaccacccg ccttggctag caatgtaccc acctttacca
    30241 gatccccttt cttcaccacg gcctgcgccg gggcgccgat atgctggctg agggggataa
    30301 tcacctgttt aggcgtagcg agagccgtaa ttttcttacc ggcagacagt ttattctcgg
    30361 ggggatgtat acctccgatt cgaaatgtcc ttagcatact attagatttt aatttagatt
    30421 tgttttttct tcacttgtaa ctttcggtgt ggcttccggt ttcacggtag cctctgcctt
    30481 cggcgccggt ttcacggtct ccgctttcgg agcgggagcg gcttccttac gaggagggaa
    30541 attcagctca tgaatagctc ctgtcggaca tacagccacg catttgcggc ataaacgaca
    30601 cttcgtataa tcgatataag ctacgttatt tgttacggtg atcgcctcga acggacattc
    30661 cttggcacat ttgccacagc cgatacaagc gttggcacaa gccttgcgag cggcggctcc
    30721 cttgtcctta tttacgcaag acacgtaaat ccggcgtgat ttaggtcctt tctttcttag
    30781 ctcgatgata ttcttcgggc aagccttcac acaagcacca caggaagtac atttttcctc
    30841 gtctacctcg gcgattcccg tagccgggtt gatgtggatg gcgtcgaaag cgcaggcgtt
    30901 cacgcagtcg ccataaccta ggcaaccgaa agaacaattc gtctcgcctc cgtaaagggt
    30961 agaggcgatg gcgcaacttt tcgttccatc ataagagttt gtacgtgggc gggcctgaca
    31021 agttccgttg caacggacaa cggctaccat gggttcggct gtacccgcct ctttacccag
    31081 tattgtagcg accttggcca tgaccgggcc accaccaacg gggcagagca atccgtctaa
    31141 tgagtcagct tttacgcaag cgcctgcgaa tccggcgcaa cccggataac cgcaacctcc
    31201 acagttcgcc ccgggaagga cttcctgtac ttgtgcgatg cgaggatctt cgtagacttc
    31261 aaatttcttg gaagcagcgt agaggaaaac cgctccgacc gccccgattg ctcctaatga
    31321 aataacggca attaaaatca tgatatatta tcaattaagt tttttcaaag taaatataaa
    31381 tcgtcttttt agtttgtcac gcattaagta tagtatacag taataaggca gtaaaagcga
    31441 taaaccggtt aacccgctcg tggtctcgtc ccattgtaga ttcgtcccga ttacgatggc
    31501 ccccacgact atcaccaaag gaatgacaaa tgccagcaat acggcctgaa gtcccatgga
    31561 attttgtccg catattatca cttcctcgtt tacgtgaaac cgtcccgacc gatcgggtac
    31621 ctcaatgatc ttatcctttt tctcggatgc cgagcacata gactgtgcgt ggcatcccga
    31681 gcatgcggat tgttgggtaa tgcggacgaa gacggtgtcg ccatcgatct tctctacaaa
    31741 tcctgtatga tttatacttt cgctcatatt tgtaatctcg acattgcaaa atcaaggcaa
    31801 aagtaagtat aatttagaaa ctatgtcacg attaacaaag tttattattc gaaatcttaa
    31861 atcctagctt accatttgta attaaaaccg aaacttaaca actcattaag ctggaaataa
    31921 ctcttgttat cctctgtttt ttccactcca tcgtcgtatc taaggtgaaa atagatacgt
    31981 gtggagaaaa agcggctgat ggccagaacc aaggtattct cgaactcccc gatggtatga
    32041 tcgccgtaag tggtaaagaa ataaagacgg gattgccagc ttacgttacg gttgaaatcg
    32101 aaggcgaggt ctgcgcggat cgtggaacct atttggctta gcttgttatt gaactcaccg
    32161 gtttcctcgt ttttcttgaa accgtgacgg ctataatcga tctcttgtgt cgtatacata
    32221 tatgtatagg agatcggcgc caagttggtg ctgaatttaa tcttcttatg cttgtcggta
    32281 aattgttttt ccagctcgta tttcataccg agaccgaagt tgatagagaa cggggctagg
    32341 aatgcggcct gtttgatgcg ctcgttctct tggtagttgg tgaagaactg ggtcttgaac
    32401 tcagcgtcga acgtatagta ccatttgttg aacgcttggt agccgacgtt gctgtgtata
    32461 cggaatacgt cgtcaccgat cttatagttc cttaaggtat ccttcggtgc cgtatatacg
    32521 ctggctttga attccagttc gttcgttact tgtaccttat ctttcttata gtcgtatttt
    32581 aaattgttct tggtgaacag gttcaagttg ctacttccac ctttatacca gttctccgaa
    32641 acgtagttct gggagaattg gacggcgctc tcgaaggccg atatccagta tctccgctcc
    32701 gggataaagc gggcgggagc gtctacgtcc tcaaaattgg catcagcctc caccttgatc
    32761 ggcaagtcct cataaatatt cttcttgatg aatttaggtt tgatcacctc attgggcaga
    32821 tccctctcgg agtagcggaa ataagtcggg taattgttct gcacatattt gtaagccatc
    32881 tcctcgaatt gtttgtttcg ttccagatct ttgaaaatgg aatctgcccg gtataggtta
    32941 tcatagggag tcctctcctt caacgaatcg aagttgtaga atatcaagtt ctcgggtaaa
    33001 taatctcccc ggaaaacgat cggcatgaac aaagggttta cgatcacggt atcccggaag
    33061 gtcatcgtat tatcgaaaat cgtggaggcg tctcgtacca gacgggccca atacatcgcc
    33121 tcgtccgaga tttccagctc gtctttcttc aagaaacgca gtaaattcgt gcttggggcc
    33181 aagggcgccg agtaagtctt gttttgcttc tcgaattgct tacgaatgtc tacgatgttg
    33241 tctaattcct cttcgctaag attgatcgcg ggaatcgtat catccgatac gacttgctgt
    33301 gcgggacgtt gaactatcgt tccggtaact agctggttct cttgactgta tgccgagcct
    33361 ccaattagtg aaagtaataa tagcgcatac acaccatgcc tcttcatcat cataatacct
    33421 tatttacatc tattagttgt agtggtcgca aaattagcta aaaagaatga tatataacat
    33481 acgatttgat atttatctgg gcaaaagtta cgatcactga ggcaaagcag gtgtgtctag
    33541 cgaggcttat acggacttgc ctcagtactc cgctggaagt actggaatac ttcgctcaaa
    33601 gtacttcagt acttcctgcg tagtaccgaa gtaattccat gagaagtact gtctttagtg
    33661 ccgggcttcg gctcgggaat cggaagagtc ctgccgaagc ccgggtcagt tctggagata
    33721 ttcagcgaga aataaaaaca ttaaatttgg catgtctcga tgaaaatcgc taactttgcg
    33781 gtttcgaaat gcaggtgtgc aattaaaaag ataactaaaa tattactatc gtggcagata
    33841 caaagtacat tttcgttaca ggcggcgtgg tctcttcctt aggtaagggt attatttccg
    33901 cttctttagg taagctcctt caagcaagag gttacaaggt tactatccaa aaatttgatc
    33961 cttacatcaa catcgacccg ggtacgttga acccttatga acatggggaa tgttacgtga
    34021 ccgtcgatgg acatgaggct gacttggact tgggccatta cgagcgtttc ttgaatgtcc
    34081 agactacccg tgcgaataat atcactaccg gacgtatcta tcaaagcgtg atcaacaagg
    34141 agcgtaaggg ggattatctg ggtaagacgg tgcaggtggt gcctcatatc acggatgaga
    34201 tcaagcgtaa cgtgaaatta ttgggtagca agtataaatt tgacttcgtg atcaccgaga
    34261 tcggtggtac ggtgggtgat atcgagtctc tgcctttcat agagagcgtt cgccagttga
    34321 aatgggagct gggtaagaac tgcctttgcg tacatcttac ttatgtgcct tatatcgcgg
    34381 cggcgaaaga gtataagacg aagcctacgc aacattccgt gaagcaattg caggagttag
    34441 gcatccagcc agacgtgttg gttttacgta cggagcatga gctgaacgcg aacttgttac
    34501 gtaaggtggc gttgttctgt aacgtggccg aggattccgt gatccagtcg atcgacgtac
    34561 cgacgatcta cgaggttcct ttggtattgc aacgccagaa gatggacgag gtggtcttgc
    34621 gtaaggtcgg tatggaagtc ggcccgactc ctgagttgaa gccttggaag gaattccttg
    34681 ccttgaagag cacggctacg gatacggtga agatcggttt ggttggtaaa tacgtggaat
    34741 tgcaagacgc ttataagtcg atcgacgagt ctttgttgca agccgctatt tacaatcatc
    34801 ataaactgga tttgcatttg ttccattcgg agaaattaaa taacgagaac gccgccgagc
    34861 aattgaagga tatggatggt atcttgatcg cccccggatt cgggcagaga ggtatcgagg
    34921 gcaagtttgc cgctatcaaa tacgctcgtg agcatgatgt cccttgcttg ggcatctgct
    34981 tgggtatgca gtgcatggtg atcgagtttg cgcgtgacgt gttaggtttg gcggatgcca
    35041 actctacgga gatggagccg aatacggcac ataaggtgat cgacttgatg gaggagcaga
    35101 agaacgttac caatatggga ggttccatgc gtttgggcgc ttacgactgt acgctgaaag
    35161 agggctccaa ggtattggag gcatacggca aggagcatat ccaagagcgt catcgccatc
    35221 gtttcgagtt caacaacgag tataagaagc aatacgaggc cgccggtatg atgtgtacgg
    35281 gtgagaatcc ggagacaaat ctggtagagg tggtagagat ccccgccttg aaatggttcg
    35341 tgggcgttca atatcatccg gagtacaaca gtaccgtggt gaatccgaat cctcttttcc
    35401 tcagcttcgt gaaagctgct atcgaaaata aaaaataatt ggtgataaat ggataaaaac
    35461 acattaatag gttttctgct gatcggtgtc gtattattcg cgtttagctg gttcaacagg
    35521 ccaacgcctg agcagttgga ggcacagcgc cgttaccaag attcaatcgc gaagattgag
    35581 tatgctcagc aactggaatt gcagaaacaa gagaacaaga gtgctttagt ggaggattcg
    35641 ttggagaacc tgccggactc ggtacgggcg caacgtttgc agcagagctt cggtgtattc
    35701 ggcgatgcta tggtgggcac ggaagattac acgaccctgc aaaatgacgt ggtcgagctg
    35761 cgtatcagca ataagggcgg acgtatttgt tatgcacgct tgaaggagta tgatacgtat
    35821 aatgacgagc ctctcgtttt gttcgacgag aaagagtcta attttaattt cacgttggtc
    35881 acggctacga accgtgtcgt gaatacgagc gatttgtatt ttaccccggt taaagggaat
    35941 gacccgaatt ccgtgatcat gcgtttgaac accggcgagg gtagtcatct ggattttacc
    36001 tataccttga aaccggatga ttatatggtg caataccaga ttctgggtac gggattgaac
    36061 ggtgtcttgg caccgagcac gaatgccttg gatttattgt gggagcagga tatccgccaa
    36121 caggaaaaag gacgtaagtt tgaggatcgc tacgtgacct tgaactacaa gttcatggcg
    36181 gacgacgtgg aacacctgag cgagtcgaag agtgacagca agcagatccc gaaccgcttg
    36241 aaatggattg gttataagga tatgttcttc tctaccgtat tgatctcgca agagggcttt
    36301 gaggctacta ccttagactc gaaagcgatt ccggaggggg atgtgttgaa acaattcaag
    36361 acgaccgctt ccgtaccttt cgacttgcaa ggtaaggaga ccacgaacct gtccttttat
    36421 ttcggaccga ataagttcgc cttgttgaag tccttcgata agggagtctc tgccgagcag
    36481 caactggatc tggagaagtt ggttccgcta ggctggggta tcttccgctg ggtgaaccaa
    36541 tatttcgtga tccccttgtt cgacttcttg ggtaagttta tccataatta tggtatctta
    36601 attcttttga tgactatcat cgtgaagatc atccttttcc cgttgacgta taagtcttat
    36661 atgtcgtccg ccaagatgcg tgtattgcgt ccgcaagtgg aggagatcaa cgctaagtat
    36721 cccggacagg ataaggctat ggaacggcag aaagcgacga tggagctata tagccgtgcg
    36781 ggggcgagcc cgatgagtgg ttgcttgccg atgttgttgc agatgccgat cttaatcgct
    36841 ttattcatgt tcttcccgtc ggcgatcgag ttacgtcacc agagtttcct ttgggcgcac
    36901 gacttgtcta cttacgacgc tatctttagt tggaataaat atattccgat catcactccg
    36961 tatttcggaa atcacatcag tttgttctgt ttgttgatga cgatcacgaa tattttttat
    37021 accaagtata atatggagat gacgaatact gggcagcaac agatgccggg catgaaggcc
    37081 atgatgtaca tgatgccgtt gatgttcttg gtgttcttca accagtatgc ttccggtttg
    37141 acgtattact atttcatctc tacgttgatc acaatcgtgc agacattgat cttccgctat
    37201 acgatcaatg aggataaatt gttagctaag ttggaggcaa acaaacggaa accgatgaag
    37261 aaatccggtt tcatgaaacg tctggaagag gctcaacgag cacagcagga gacgttgcgt
    37321 aaacaacaag aggctaagaa aaaacgatag gataatagta attgttgtcc ttgaaaaagg
    37381 tccctttatc tgcttattgg tagataaagg gatttttttt gtatatcttg gctcctctac
    37441 ttgaaaaaca agacgtcttg atcatgattc tatttgttta tttgtattta ttcaaaactt
    37501 tttgtttgtt tgcattgttt tgtattcaaa agattgatga ggaaattgat tttttctata
    37561 ttgaggaaat agggaggtta taaataagag attttgtcaa tgacaaaaaa tgaacgatcg
    37621 cttcaatggg taatagcggg aatattcttc gtagtatgct ttgctttctt tcaatggatt
    37681 tacccaaacc atttgttctt caaagagcag atgaggattt ttttgtatac caccgattat
    37741 tttatctcgt tctgggatga gccggcttgg ttgagctgtt atgtggggaa tttcttgata
    37801 cagttcttcc atttgactgt gataggcccg ttaatcgtga cgtgcgtgtt gttgctctta
    37861 tggtactact ctatgcgggt tttacgcaag ttcgggaatg gtaatatggt ctccatatat
    37921 gcgttgtttc cggtagcgtt agagtgggga ttgatttgcc ggttgtcgta tagtatagcg
    37981 tctacgctta cgttgatttt cgtgctatgg ctcttcttgg gatacatccg gattaagaat
    38041 aagagaacgt ccgtttgggt ggcttttata cttcttccca taatttatag catggtcggt
    38101 agccggctgt ttgtcttctc cttgatggtg atattctatg agggagccaa gaataggaaa
    38161 cggtggtggt tctggctttc tcttttgtta tcgagttatt tatatccgtt gttcatgcgt
    38221 catttttatg gattgagcat tgaggaggcc tataaatatt cccatgtgga tggcttgagc
    38281 gtatatttcc ccgctttagc gttgattcta gagatattcg ctttggagat taaaagtata
    38341 cgtaggatac gtctgaaccg gcatagcttg cttataacct ttttagtcgt atttggattc
    38401 ttttcatttg ttatagcggg tacgaaccgg aagcgggaaa aggttctggc tgtagaccaa
    38461 gcgatctata ggggtgattg ggagcgagtc ttggatttgt ctgccggatt tgattctccc
    38521 gatatcttgg taagttatta taggaatatc gctttctcca agaagaacga gttgccccag
    38581 aatttgatgg atcattatca acgaggggcg gacgccttgt tcttaccgat cgatttgagg
    38641 tcttctatac ttcccgtgtt tttcagtaat gaggtgtatt atcaattggg agatatggat
    38701 atggcccgcc accgggcgat cgaaggaatc ttgttcagcc ctaaacaaag aagtgtacgg
    38761 cagatcaagc ggctggtgga gattgatatg cggcgagggg atattgagga ggctagaaaa
    38821 tacctgaacc tattggacgc gacgttattt tatcactcat gggcaaggtc gaaggaggaa
    38881 cagttgaagg gtgaggagac cttgtcgatg gagaaacgtt tgccgaggaa aagtgattgg
    38941 gagcgagagc acgacatact aatgtccata tccgattatc cgggcgtact gtcaagtttg
    39001 atggcggaat atccggaaaa taaacaggca ttggattatt tgttgtgcta ttatttactg
    39061 aacgagaatt tgaatagttt taagaatgcg ttcgatactt attataaagg aaaatttgag
    39121 gttgtacccc gtttgtatga ggaggctttg gtacaagtct tatctaaaag ctcggacgag
    39181 gaggtggccg gttatcagat acctcaagat gttatcgaga attaccaaga ttacatccat
    39241 tgtaaatcgg gtagaaaagc aaaggaggaa ttacgagaac gttattcctc cacctattgg
    39301 tactactctg actatattca ttgaataata gtgtaagtga tcagcggttc gcgaggaagg
    39361 ctaaggcttt ctccatgtcc tccggtgtat ctataccgat cgtttcttgc tctgtgatgc
    39421 cgaccttgat tttatatccg ttttccaacc agcgtaattg ctcaaggctt tccgccagtt
    39481 ctaaagcgga ttgaggtaat tgggtgattt ctttcagcac ttgcgcacga taggcatata
    39541 acccgatatg cttgtaaaag gtatgactcg gcaaccattc cgtatatttc ttgccccgga
    39601 tataaggaat aatagatcga ctgaaataca tagcctcgtt gttattgttg agtacgactt
    39661 tcggggaatt gggattgaat agggtactct cgaaatcatc gtccgaacgg aaaggcttta
    39721 ccaatgtcgc tatttgcgtg tttgcgtcgg cgaagcaggt tttgatcgtc tggatttgct
    39781 cgggatggat aaaaggctcg tcaccttgga tattgacaat cacatcatac ccttcgccta
    39841 ttttctgata agcctcgtag caacgatccg taccgctacg atgttgatcg gaggtcatga
    39901 cgacttggcc gccgaaggtt ttaaccgcat tctctatccg gatatcgtcg gtagctacgc
    39961 aaacggagtc taagacatcc tttacttgct catatacacg ttgtatcatg ggctttccgt
    40021 tcatatccgc taatggcttc cccggaaaac gggtagaggc gtatctcgcc ggaataattc
    40081 ctataaactt catcattcta tatcattttg ttaactggtt actacttttc cttcacttaa
    40141 ctggatcaac ttatcccgtt cgcctacgat ccatacgata tctccttcct cgaaaaccgt
    40201 actaggaggc ggattcttga tcgagctact tccacgttcg ataccgatta ccaagcaagc
    40261 ggctttatca cggataccgg actctatgat ggagcggccg atcaatcggg aaccttccga
    40321 gataatgatt tgctccatat tcatctcttc ctttcttgtg ttcgattgct cggcgtatga
    40381 tttcttgtag cgttcctcca gatatttcct aaagtgctcc agatcatcat ctgcgccaac
    40441 tactaccagt ttatcgaacg ggtagagccg ctcgtctcct cccggtatgt tgattcgctt
    40501 ctctccccgg ataatcgtta cgatatttac gttgcacttt tgcctgaagt ttaattcttt
    40561 caggcttttt cccatactgg gggaattctg cttcacctcg aaatctgcta aatggagatc
    40621 tcgttctaat aagtggttcg cgaaacgctg gttaatcggg gcttttcgct cttgctccac
    40681 ttctctcgct acaaggttac tgaaaaaatg ccgttccatc aagatcgact gcctctttag
    40741 ccgtttggag aatatcatta atacgataac agcggaggcg accgccagca taattcctag
    40801 cgcagcattc aataaccgtg cgactggaag catgacgaga ccgatacaga gcaggattct
    40861 gaggatcacg agtgatacta ggggaccccg gttatattta ttatcgttcc ataattgctg
    40921 gaactccacg gaatgattct ttttcatcat gatcgcccgc aacatcgggg agatcagagc
    40981 taggattaag atcaaggaga ttagacttcc ttggatgccg ggcaaatgtt tacagatgaa
    41041 cggagtcacg atttgtagcc ataaaaagat aagtactagg cagacggcgg tataagtacc
    41101 gacgatgcgg accaaggctt ttagtaactt attccatgcg cttttttgac ggatcgtatt
    41161 ggaaccggat gaatatcgct ccaagaactg tttccaattc tccggtatga tccgctccgc
    41221 ccatttgtag gtaggttccg ctagccggat catataaggt gtgaagaatg tcgtgatcac
    41281 ggatacggcg acaacgatcg gatacagata ttgatccgtc acgtttaatg atagtcccaa
    41341 acctgcgatg atgaaggcga attctccgat ctgcgctaac gagaaaccag actggatggc
    41401 tatttttatc ggttgtccgg acagtaatac tccgaaactg gcgaaacaaa tctgtccggc
    41461 catgactacg agcgtgataa tgaaaatcgg gattttatac tcccagagca tctgaggatc
    41521 gattaacatg cctacagaca cgaagaaaat cgctccaaat aagtctttta cgggttttac
    41581 caaatgctcg atccgttcag cgtcaatggt ctcggccaaa atagaaccca tgacaaaagc
    41641 tccgagagcc gatgagaatc cggcttttgt ggcgatcata accataccaa ggcatagccc
    41701 gatgctcacg atcaacagag tctcctcatt taggaagctt tttgcctttt tcagaaaaga
    41761 ggggatcaaa tagatcccga caacgaaaca gaataaaagg aaaatgccta atttgaccac
    41821 gctatccagc atctccatgc cttccacgtg tttacttacc gctacggtag aaagtaatac
    41881 cattaataat acggcgaata gatcctccac caccaagata ccgaatacga caccggcgaa
    41941 tcgttggtta cgcaatccca tgtcgtcgaa tgccttgaag ataatcgtcg tggaagacat
    42001 cgataacata cctccgagga aaagactgtt catatgtccc caacccagtg ataagcccgt
    42061 gatatatccc gctgtcatca tacctataac aacggttatg gctccaatga cggcggttcc
    42121 tcccaccttc atcaacttct tgaaactgaa atcgagcccc aaagcgaata acaggaagat
    42181 aacgcctata tcagcccaga tacggatact ttccacatct gtaactgtcg gtatttgctc
    42241 gatggaaggt ccggcgagta ttccggctac gatatacccc aatacgaccg gttgctttaa
    42301 ctttttgaat aacagggtaa ccaacccggc ggatatgagt atgaccgcaa gatctgatat
    42361 tagcgcaggt atctgagaca tcgtttattg ttttttcgat tgccaaagtt aggtatttat
    42421 tttaattttg tgtctcaaaa cagaagccaa aatgaagaag aaacatccga ttgaagcgct
    42481 tatagagcaa ggggaacatc aacaacttga tttcaagttt gaggtgagcg acagcaagaa
    42541 gattgcccgg acattgagtg cgttcgcgaa tacagatggc gggcggctgc tgattggagt
    42601 gaaggataac ggcgctattt ccggtgtgag aagtgaggag gaatattata tgatcgaggc
    42661 tgcttctaaa atgtatacgc atcccgaggt gccgtttaca gctaagcgct gggatgtcaa
    42721 cgggaagacc gtattggagg tctatatcgc cccaagcgat gagaaaccgc atacggcacc
    42781 ggataaagac gataaataca aggcctatat ccgggttgca gacgagaata tattagcgaa
    42841 cgaagtcctc atgcaagcat ggaagaagca gaaaaccaaa gaaggtacat tgctgaaaat
    42901 aagtaagccc gtcgagatcc tgttttcttg gctcgacgag catccttata tcagcataaa
    42961 gcaattttgc cgtatcgccc atatcaatta ttatgcggcc cgtaacatcc taagtgattt
    43021 gatggctatg ggagcgatgg aatatgtcgt gatcgataaa tgtattgcct ataaacggat
    43081 cgcatagact cgtttatagg ttgattacat agacttgcgc gctctcgaat ctgacgactt
    43141 tgataggagt ccctttctcg atgaagccag actccgatac gccgtcatac aactctccct
    43201 cgatagatac tttacccgaa ggacgtaaaa cggtagcggc cgtgccctct tttccgatca
    43261 gttgtgtcaa attggggctg gataccgctt tttccaaatc agcgtttaat gccattttct
    43321 ttagcggtcc tttatgtcct attttgttgg ataaccatat cactaacgtg aatccgatac
    43381 ccagacctaa tagaaccgtt aaggcggctc tgcccgtatc cattccagat acgttttgaa
    43441 aatcaaaaac agtattgttc agtaagctca tcgtaagtcc gccgaccacg agaataattc
    43501 cacttatccc cgctatgcca aagcccggga tcacgaatat ctccaacatt attaatataa
    43561 cgccgagaat gaataacagg atttcccagt tttcagccaa cccgtccata tagagaggag
    43621 cgaagtaaag gatagccgct attatcgcgg cggcggatgg aaaaccaagc cccggggttt
    43681 gcatctcgaa gtaaatacca ccgatgataa taatgattaa taagctctgt attaccggac
    43741 tcataaagaa accttttaca ttatcgaacc atgagggttc ataactttta atctcatagt
    43801 ccttacatcc gatatattct gtgattactt gatccggact ctcggcgatg ccatcgcaat
    43861 aaccccattt gagtgcttct tgagaggtaa gtgttaatac cttaccgcta tcgatgaggt
    43921 tggggacgat cactctgtca tcgaccatcg cttcggcgat taaaggatct cttttccatt
    43981 tatagatcgt gtcgccgttt tgtataagcg tatctttccc ttgtgcctca gccgtcgaac
    44041 ggatcatgga acgcatataa gattgatatt tatcaggtag agccgcaccc gtttgattga
    44101 caaccgttgc cgcacctata ttcgcccctt tccgcatata gattttcttg catgctatgg
    44161 aaattaaagc acctgctgaa gctgcgttat tatcgataaa tacatatact ggtatgggac
    44221 tatataaaat agccgttcgc atagaatcgg cagattccag taatccgccg tatgtgttca
    44281 tatgcaataa gatggcatcg gcgttcaatt gcttagcctc tgataatccg ttatggagat
    44341 aaatccacgt ggtgttatcg atctcttttt ttatatcaat cgtatatatt aaggacttct
    44401 ctttagcctc tgattgaaga gagattgcaa gtattaatac tatagctgtt aatattgtta
    44461 ataaacgttt catcttgttt gtattatatt cgtttttaat atttggttga aaattgtaac
    44521 tggcttgttg taaatgttga tttttgtaac ttgtgcaact tgtaaataat actcattttc
    44581 agtaagattt acaacaaaaa tattaagtta cgatttttaa tattaatatt tatcaaagaa
    44641 ctgtatatct ccatttttaa tttatatatt tgttgcatcc ttcaatgttt gagggataat
    44701 acttatacag tattaaactt tatttaacta gtaaaaatat gaatgcgttg caatttcaga
    44761 aaaaattatt gagcatgcaa gaaaacatga tgaattttgc gcttatgctt acagcgaata
    44821 gggatgatgc ccaagatctg atgcaggaca caacgctgaa ggttttagac aatcaagaaa
    44881 aatttgtaga caatatcaat tttaagggct gggtcttgac tgtgatgcgt aacattttca
    44941 ttaacaatta tcacaagatc gttcgcacgc aaactgtcgt agatcaaggt gtcgacttat
    45001 ataacttgga tgtcgtgaac gattcaggtt ttgactctcc ggatggcgct tatcaaattc
    45061 aagagatcac gaaagcgatc aacggtttga acaatgagtt gaaggttcca ttctctatgt
    45121 ttttgagcgg ctataagtac aatgagatcg ctgataaact ggatgttcct ctggggacgg
    45181 ttaagagccg tatttttttc gctcgacaag aattacaaaa agttttaaaa gattttcgtc
    45241 aaggataaaa tttacttta
//
LOCUS       DBMDTB010000022        45001 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_335_length_45001_cov_11.539644, whole genome shotgun sequence.
ACCESSION   DBMDTB010000022 DBMDTB010000000
VERSION     DBMDTB010000022.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 45001)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 45001)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45001
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_335_length_45001_cov_11.539644"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(354..1649)
                     /locus_tag="ACZPB4_05575"
     CDS             complement(354..1649)
                     /locus_tag="ACZPB4_05575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HIR1097725.1"
                     /translation="MSKIQEWVYNLLVQMGLISENSSYLDNIVILLLIIAVTVGIDYS
                     CRYIFLGMFKRLARKTKNQLDDLIVDRKIINKMMHMIPAILIYILLPFAFSAEETPKI
                     LIVLQKLCQIYIIAVSLRFINASLNLIHEIYNKKDSFKNKPLKGFIQILQVTVFFIGV
                     ILIISILINKSPVSLLAGLGASAAILMLVFKDTILGFVAGIQLSANDMLRAGDWITMS
                     KYGADGTVIEVTLNAVKVRNFDNTITTIPPYALVSDAFQNWRGMSESPGRRIKRSINI
                     DMNSVHFCTPEMLEKFRKISLITDYIDGKEQELDEYNEEHHIDSSIWVNGRRQTNLGV
                     FRAYLVRYLRSLPEVSKELVCMVRHLQPTDTGIPIELYCFSSNKVWVEYEGIQADIFD
                     HVLAVIPEFGLSVFQNVSGADLKNIIIKLPVGSQPSECF"
     gene            complement(1719..2888)
                     /locus_tag="ACZPB4_05580"
     CDS             complement(1719..2888)
                     /locus_tag="ACZPB4_05580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005815001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HIR1097726.1"
                     /translation="MINLGSWMNKVLTGWGVDEKIANTFDEAIIAILLVAVAIGLDYL
                     CQAIFVGGVRSIVKHTHYKWDTLLIKRKVVHYLVHTIPGILVYVLLPMAFIRGKELLF
                     ISQKICAIYIIFSLLLALNGLLLMMLDLFNQQEKMKNRPMKGFIQVLQVLVFFVGGIV
                     IIAILVNKSPATLFAGLGASAAILMLVFKDSILGFVAGIQLSANDMLRPGDWITMPSA
                     NANGIVQEITLNTVKVQNFDNTISTIPPYNLVNSSFQNWRGMVESGGRRVMKSIYLDL
                     NTIKFCTPEMLDTFRKEIPLLADYQPDKDVVPTNSQVFRVYVERYLTSLPVVNQDLDL
                     IISQLQSTEYGVPVQIYFFSRNKIWKEYERIQSDIFDHFFAMIPKFELKVYQYSD"
     gene            3031..5880
                     /locus_tag="ACZPB4_05585"
     CDS             3031..5880
                     /locus_tag="ACZPB4_05585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HIR1097727.1"
                     /translation="MDSMRSLLSTSDFLQVREHKLSNDLTVWLNEDHSQPKIFGAVVV
                     KAGAKDSPNTGIAHYFEHMMFKGTDKIGTIDYESEKVLLDIIAEKYDALADTEDPKMR
                     AHLQQIINDLSVRAAEYVIPNEFDRLISRFGGTKLNAGTSYDYTLYFNTFSPQYISQW
                     AEINSERLVNPVFRLFQSELETVYEEKNMYGDTMASVAIEKLTERYFYPHPYAYPIIG
                     SAENLKNPRLSEMRRFFEKYYVASNMGLILSGDFDTEEVLPILESTFSRIRKGKPPHR
                     DIVTLPPFKGREKVSVRIPMPFVKIMALGFRGVPANHPDQVALNIAVSLLNNSNGTGF
                     LDKLTVDHKVMGAMAVNQSMNEAGILGLLVFPKFFFQTYAAAEKLVWKQINRIKEGDF
                     SDEMFQSLKLEQKREYASKLEDINSRAEVMMRIFSQGKSWQDYLDEVTRIDALSREDV
                     IEIAKKYFTENYMYVTKKTGRYPKTILPKPDYSPIIPKNSDASSAYVERLEKIPVQEL
                     KPHFLDFEKDAEVVSLRPLVTLYKTHNSVNDIFSLTLSYGVGQLELRDLDKLSAYLPF
                     VATESMSFEVFRGKLQELGSTLTFDSTDSEFLVVVNGFDGHFTQTMALVGDFLRHAKP
                     DDKKLRQIVDEAKVTEKSLFNSSENVADMLLEKVKFGEQSRYLTKLSFAEIKKLKGKM
                     LLDTFSKVRSVACNLHYCGTLSMEEAARQIKQHLPLEEVSIPSNSPYIRDLMTYDKPT
                     VFFMDMEDVTQSIIYAYMYIDPLKAKEDRPISRLFSAYFGGDMSSLMFQEIREFRSFA
                     YQVNARLKHPPLNRSEKPASFVMKLATQTDKMIDAMEVLENLVHDMPERPERVESVKQ
                     TIRNWVNNEYPTSRSLSLKIAGFRREGYESDPNKDYLEVIDRMTMEDILRFYRENIQD
                     HLMIYAIVGNSKSMDMEKLSKFGQIVKVTKKDIYR"
     gene            5880..6335
                     /locus_tag="ACZPB4_05590"
     CDS             5880..6335
                     /locus_tag="ACZPB4_05590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007656906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4268 domain-containing protein"
                     /protein_id="HIR1097728.1"
                     /translation="MYSKEELKNLKLEFWESFAAFCEVQPYLRGRKKIWTLYDTKVKG
                     VELKFDANRQGAYVILEVNHRSEDLRLEMFERLTWYKETLEQDFPEGLIWDICFVREN
                     GRQVARIYVAKEGLDLHRRAHWGDFFTFMASQMYLLERNFMGIAEYLRE"
     gene            6345..8873
                     /locus_tag="ACZPB4_05595"
     CDS             6345..8873
                     /locus_tag="ACZPB4_05595"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HIR1097729.1"
                     /translation="MNLKVFIGACVLSGLVACSSVKQDEAGLSRPGVSLELAQFRKEH
                     FSNVRYNLFFSIPESRDEAIRGKVELSLRLDEKQPLIIDFRGEPEQVTSVTLNGGDIS
                     YEVKDEHIVIASDWVAVGENRVAITFTPADQSLNRRDEFLYTLLVPDRARTVFPCFDQ
                     PDMKSFFTLTLEVPSTWQAVANGAITQTDSTSVSGRNRISFKETEPLSTYLFSFVAGK
                     LTREVYSRNGRDISIYHRETDPKKIAQCPAIADEVFDALEWQEDFTGIPYPFAKYDVI
                     ILPGFQYGGMEHTGATLYTDRRMFLDEHPTLNERLSRSSLIAHETSHMWFGDYVTMKW
                     FDDVWTKEVFANYFASRIVEPLYPDVNHRLNFIRDYIPASYSEDRTSGANPIKQDLDN
                     LRNAGLVYGNIIYDKSPVVMEMLVRVLGEEAFQQGIREYLTTYAYGNATWEGLIRILN
                     KYTEEDLAAWSEVWVNQKGMPEITASVKDGELVVEQRDPLGRGLKWPQELTYRVICGT
                     DSEEIPVSLEGNSDSFRMKLSFLPNGNCVILPNTNGRGYGFFKITEGESSGLWSVLRL
                     SEDEVLKGSLLITLYENLRWKTISPQGFRDEMLAYLPNESNSLLFSMALSYLGDCQRI
                     FPSDSRPLEQALWKIVTTNPVSQHRLQAFRLYRSIADSEEAVQRLYTLWQERKAPKDC
                     ALSESDYIGLSYILAIHLPEKADEIIATQLSRIQNPDRKKEYQFISPSVSPRKEERDS
                     VFASLLIAGNRRVEPWASSALANLNHRLREQESVAYIRPALEAMPEVQRTGDIFFPTA
                     WVRSLLSAHTSKEAREEVDAFFTAHPDFPLMLSNKIKQQASHLY"
     gene            9338..10189
                     /gene="hisG"
                     /locus_tag="ACZPB4_05600"
     CDS             9338..10189
                     /gene="hisG"
                     /locus_tag="ACZPB4_05600"
                     /EC_number="2.4.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005789131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003879 - ATP phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase"
                     /protein_id="HIR1097730.1"
                     /translation="MLRIAVQSKGRLYDETMMLLEEAGIKLNRGKRILLLSAKGFPVE
                     VLFLRDDDIPQSVANGVADIGIVGENEYVEKGQEAKLIKRLGFSKCRLSLAIPKDEEY
                     KGAEWFEGKTIATSYPAILRSFLEERGVKADIHVISGSVEIAPGIGLADAIFDIVSSG
                     STLVSNQLREVEVVLPCEALLIANNNLSKEKLEILDELLFRFEAIQVAEGKKYVLLNA
                     PKEKLDEIIEVLPGMKSPTITPLANDEWVSVQSVIAEKHFWEIIGKLKSLGAEGILVL
                     PIEKMIV"
     gene            10191..11471
                     /gene="hisD"
                     /locus_tag="ACZPB4_05605"
     CDS             10191..11471
                     /gene="hisD"
                     /locus_tag="ACZPB4_05605"
                     /EC_number="1.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004399 - histidinol dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol dehydrogenase"
                     /protein_id="HIR1097731.1"
                     /translation="MEIIKYPGREEWSSLIKRPALDVTTLFDTVRTVLDEVREQGDTA
                     VKAYEEKFDKVQLSSLQVSEEEMREADALVAEDLKQAIRTAKANIEKFHASQRFEGKK
                     VETTPGVTCWQKAVAIEKVGLYIPGGTAPLFSTVLMLAVPARIAGCKEIVLCTPPNRE
                     GKVHPAILFAAEVAGVSKIFKAGGIQAIAAMAYGTESVPKVYKIFGPGNQYVTAAKQL
                     VSLKEVAIDMPAGPSEVEVIADETANPDFIAADFLSQAEHGVDSQAILVTASETIVEP
                     VARAIQEQLDRLPRKEITEKSLAHSRIIVLKDSQEVVDFTNQYAPEHLIIQTADYTAI
                     AERIENAGSVFMGPYTPESAGDYASGTNHTLPTNGYAKAYSGVNLDSFIKKITFQEIT
                     SDGIRALGSTIQTMAANEHLDAHRNAVTIRLNTI"
     gene            11468..12505
                     /gene="hisC"
                     /locus_tag="ACZPB4_05610"
     CDS             11468..12505
                     /gene="hisC"
                     /locus_tag="ACZPB4_05610"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004400 - histidinol-phosphate
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HIR1097732.1"
                     /translation="MKDLKDLVRPNVWNLKPYSSARDEFHGDASVFLDANENPWNVPY
                     NRYPDPLQWKLKDRLAVLKGVDRSSIFLGNGSDEAIDLVIRAFCEPGLDSVVTISPSY
                     GMYEVAADVNNVECRKVSLDENFDLDADRVLESADEWTKVIFLCSPNNPSGNSLDRGS
                     IYKILKNYEGIVVIDEAYIDFSAYPSFLKELSGFPNLIVLQTLSKAWGAAGIRLGMAF
                     ASPEIIGVLNKIKYPYNVNQLTQEKALEFLNDEATMKHQVNEILTERNRLEKILSEPP
                     FSYQVYPSDANFLLVNVGKADAMYNGLVKKGIVVRNRSNVQKCRGCLRITIGTPKEND
                     SLLNAMKNMKL"
     gene            12502..13638
                     /gene="hisB"
                     /locus_tag="ACZPB4_05615"
     CDS             12502..13638
                     /gene="hisB"
                     /locus_tag="ACZPB4_05615"
                     /EC_number="3.1.3.15"
                     /EC_number="4.2.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004401 - histidinol-phosphatase activity
                     [Evidence IEA];
                     GO_function: GO:0004424 - imidazoleglycerol-phosphate
                     dehydratase activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     histidinol-phosphatase/imidazoleglycerol-phosphate
                     dehydratase HisB"
                     /protein_id="HIR1097733.1"
                     /translation="MSTRKRALFIDRDGTLVKEPPVDYQLDSLEKLEFVPKVMRNLYF
                     ICERLDFEFVMVSNQDGLGTPSFPEETFWPAHNLMLKTLEGEGIVFDDILIDPSFPED
                     NSPNRKPRTGMLTKYMTGEYDLENSFVIGDRLTDMELAHNLGAKGIWLRPEEGAETEL
                     AAYATSLSPAYITDDWDKITEYLFAGERRAVVRRATKETDIYVDWNLDGTGKTSISTG
                     LGFFDHMLDQIGKHSGTDLTVRVKGDLEVDEHHTIEDTAIALGEAMLKALGDKRGIER
                     YGYCLPMDDCLCSVALDFGGRPWLVWDAEFHREKVGDMPTEMFLHFFKSLSDAARMNL
                     NIRAEGTNEHHKIEGIFKALARSIKMAIRRDIYRFELPSTKGLL"
     gene            complement(13769..14716)
                     /gene="cysK"
                     /locus_tag="ACZPB4_05620"
     CDS             complement(13769..14716)
                     /gene="cysK"
                     /locus_tag="ACZPB4_05620"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011203747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HIR1097734.1"
                     /translation="MARIARQLTDLVGNTPLLEFSNFNASKGLKAQVIGKLEYFNPAG
                     SVKDRIALAMIEDAEAKGLLRPGATIIEPTSGNTGVGLAFVSASKGYKLILTMPDTMS
                     AERRNLLKALGAQLVLTPGAEGMKGAIAKAEELRDATPGSIILQQFENPANPAVHIRT
                     TAEEIWRDTDGKVDLFVAGVGTGGTVSGVGAGLKAHNPNVQIVAVEPSDSPVLSGGKP
                     GPHKIQGIGAGFIPKTYNGEVVDKILQVTNDDAIRTSRELAGKEGLLVGISSGAAVYA
                     AVELAKLPENEGKTIVALLPDTGERYLSTVLYAFEEYPL"
     gene            complement(14886..16250)
                     /locus_tag="ACZPB4_05625"
     CDS             complement(14886..16250)
                     /locus_tag="ACZPB4_05625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0015288 - porin activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux transporter outer membrane subunit"
                     /protein_id="HIR1097735.1"
                     /translation="MKNNIILFAVATLALNSCGIYKKYEPVATLPENLYREEIAPADT
                     FSIGNISWRDLFTDPALQSLIERGLANNTDLRIAHLKVQEAEAALMTSRLSYLPSLSL
                     DPQGTTSSFDKAKASWTYNVPVSASWEVDIFGRLTNAKRQAKAALSQSQAYSQAVQTQ
                     LIANIANLYYTLLMLDRQYEITTETAVKWQESLRATQALMAAGMTTEAAVSQTEATCY
                     SIETSVKDLEQTIRETENTLAVLLGETPQDIERGRLEEQSLTPDLAIGIPVQLLSNRP
                     DVRSAEYALAQAFYGTASARSNFYPSLRLSGSAGWTNSAGSYIVNPGKLLLSAVGSLT
                     QPLFNKGANIAQLKIAKAQQEEAKLTFQQTVLNAGKEVNDALTQAQTAKGKIDLRTHQ
                     IESLEDAVRSTQLLMTHGNTTYLEVLTAQQTLLSAQLSQVTDRFDELQATVNLYQALG
                     GGRH"
     gene            complement(16279..19482)
                     /locus_tag="ACZPB4_05630"
     CDS             complement(16279..19482)
                     /locus_tag="ACZPB4_05630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0042908 - xenobiotic transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HIR1097736.1"
                     /translation="MKVSTFIERPVLSAVISITIMVAGIIGLFTLPVEQYPDIAPPTV
                     MVSTTYFGANAETMQKSVVAPLEEAINGVEDMTYMTSTATNSGTATITIYFQQGTDPD
                     MAAVNVQNRVSKATGQLPAEVTQVGVTTSKRQTSMLQIFSLYSSDGSYDENFLCNYIS
                     INLKPEILRISGVGELMVMGGDYSMRIWMKPDVMAQYKLIPSDVTSVLAEQNIESATG
                     SLGENSDETYQYTMKYSGRLLTPEEFGDIVIRSTEDGEVLKLKEIADIELGKESYAYI
                     GQTNGKPGISCMVFQTAGSNATEVNNKIDAFLEEASKDFPKGIEVVKLMSTNDFLYAS
                     IHEVVKTLIEAIILVILVVYVFLQDIRSTLIPLVAIVVSLIGTFAFMTVAGFSINLIT
                     LFALVLVIGTVVDDAIVVVEAVQARFDVGYKSSYMASMDAMKGLTSAIVSTSLVFMGV
                     FIPVSFMSGTSGTFYTQFGLTMAAAVGISTVNALTLSPALCAILLKPYINEDGTQKNN
                     FAARFRKAFNAAFDSVIKKYKHGVLFFIKRKWLAWSLLACSIVLLIVLMNTTKSSLVP
                     DEDQGTVFVNVSTASGSSLATTNKIMTNIEQRINQIPQLQSYSKVSGYGLLAGQGSSF
                     GMFILKLKHWDERPDKEDNVQAVIGQVYGRTADIKDATIFAIAPAMIPGYGMGNALEM
                     HTQDKAGGDLTTFFNTTQQYLAALRERPEIATAYSTFDIKYPQWRVDVDAAKCKRAGI
                     TPDAVLSTLSGYYGGQYVSNINRFSKVYKVMIQSDPKYRLDEASLNNTFVRMSNGEMA
                     PLSQFITLTKVYGAESLARFNMYNSIAVNAVPANGYSSGDAIKAVKETAATSLPKGYG
                     YDFGSITREENQQSNTTIIIFGICILMIYLILSALYESFLVPFAVILSVPMGLMGSFL
                     FAKFMGLENNIYLQTGLIMLIGLLAKTAILLTEYATQRRLSGMSLTSAALSAAKVRLR
                     PILMTALTMIFGLLPLIVSNGVGANGNRSLGTGAVGGMLIGTLALLFIVPCLFITFQY
                     LQEKLRPIQFERSLDWQVQEEVKEAAEERKEYLDSKK"
     gene            complement(19488..20597)
                     /locus_tag="ACZPB4_05635"
     CDS             complement(19488..20597)
                     /locus_tag="ACZPB4_05635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HIR1097737.1"
                     /translation="MKKQNRLMKTAIALWCIVAVGCKQSPVIQQSSGYATMTVFTSEK
                     TLSNNYSASIRGKQDIDIYPQVSGFITKLCVTEGESVKKGQVLFIIDQVPYQAALNTA
                     IANVEAAKASVATAQLTYDSKQELYKNKVVSEFDLKTAYNTLLSAKAQLAQAEAQEIN
                     ARNNLSYTEVKSPSNGVIGTLPYRVGALVSANLPKSLTTVSDNSEMYVYFSMTENQLL
                     ALTRQYGSKDKALENMPEIELQLNDKSLYPQTGKIETISGIIDQNTGTVSLRAAFPNE
                     EQLLNSGGSGNVIIPVTYDNCVVIPQAATFEIQDRVFVFKVVDGKTQSAPVEVTRVNG
                     GQEYIVNAGLNSGDVIVAEGVGLLREGTPIEVKQN"
     gene            20748..21581
                     /locus_tag="ACZPB4_05640"
     CDS             20748..21581
                     /locus_tag="ACZPB4_05640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIR1097738.1"
                     /translation="MNPFEIERGESFIIGDSDLRELLDRPYKSGYGMILFCYKGTANI
                     SVDLSRWDIRRNTVIVLIPDTILTLNASSEDFKVQYISFSKVLFDEAVFRLDPPFFRF
                     IKDSPCYTHPADQEETINVIIRLFWLIYMDRNNVYRDMIVKNQLQCFFLNMYDKTRYS
                     FSSRQQNGCNRGEELFHKFINCIHAHYLDQKEVSFYANELCISPRYLSTITRQVAGES
                     AKTIIDRHIILETKVLLRTTEMTVQEITNHLNFPSQSYLGRYFKKHTGESPIEYRMKR
                     K"
     gene            complement(21633..22817)
                     /locus_tag="ACZPB4_05645"
     CDS             complement(21633..22817)
                     /locus_tag="ACZPB4_05645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="HIR1097739.1"
                     /translation="MLKKILSNTIVRLILAVLIGLLVGLAVNESVLKAVMIVKQITGQ
                     IIFFLVPLIILGFVAPSIARLKSNASKVLLFAFSIAYLSSVGAATFGAVVGYELIPHL
                     HIQTASEGLKDIPPMLFNLEIPPVMSVMSALVLAVMLGLSTAWVKSEEMERLLEVFQN
                     MVLKLVERVLMPVLPLFIAANFCVLSYEGAITKQLPIFLSVLLIVIICHYIWLTLLYV
                     VASIYSRKNSWGVLKYYGPAYLTALGTMSSAATLGTALTCAKKSKILREEVIDVTVPL
                     FANIHLCGSILTEVFFVLTVSQILYGSMPDFTTMFVFIILLGFFAIGAPGVPGGTVLA
                     SLGLIIAILGFDEAGTALLLTIFALQDSFGTACNVTGDGALTLITDTFDQGQTGKAST
                     AL"
     gene            22950..23633
                     /locus_tag="ACZPB4_05650"
     CDS             22950..23633
                     /locus_tag="ACZPB4_05650"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HIR1097740.1"
                     /translation="MKNMKQALLVAGCLLATTTLFAQTEKGDWAQFGRYAEANKTVKV
                     PSNVVFMGNSITDGWWPADSTFFIRNNFVDRGISGQTTSEMLVRFRQDVINLKPKAVV
                     ILAGINDIAHNNGVIALENVFGNLVSMAELAKANHIKVIFCSVLPAYDFPWRPGMQPA
                     DKVIQLNKWIKEYADKNGLTYVDYHSAMKDERNGLPANLSKDGVHPTLEGYKIMEKIV
                     LEAIHKTVK"
     gene            23638..26154
                     /locus_tag="ACZPB4_05655"
     CDS             23638..26154
                     /locus_tag="ACZPB4_05655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase domain-containing protein"
                     /protein_id="HIR1097741.1"
                     /translation="MRNYLLALSCCTALSCCMQVKVSEVYTAAAENSLRAPAVPLVTI
                     DPYTSAWSFADQLNDESVRHWTGRDYPLLGGIRVDGKSYRFMGMDDIQVTSVIGMASD
                     GLWEADYTMSQPAGDWFAEAYDPKSWKRGKAAFGTEDNPNRSTLWSTGDIWVRRTFDW
                     PSDEQKDALYLQYSHDDNIEVYLNGKQIAVAGNGLDYDLLKEIPEAVAESLKPTGNVL
                     AAHCRNNGGGAYVDMGIMRKVKRGDTFDEKAIQKSMNVMPTQTFYTFECGGVSLDLIF
                     TAPFLLNDLEAMTSPFNYITYQVRSIDGKDHDVQLYLEATPQWAVNTIDQEVTFEKTE
                     TPDLIYLKTGTIDQEVLAKTGDDVRIDWGYFYLAIPKKPGVSATIDEYYATKKAFMTT
                     GNLPAGSQSLSSDMREQMTVLAYTDPIGKVSKETVSGHLMIGYDDLYSIQYFQDNRMP
                     YWKHDGKVDIHQAFEKGEASYEDLMRRCGSFDSSLMSETSAVGGKKYAELCAIAYRQA
                     IAAHKLVTDKEGTLLFLSKENFSNGSIGTVDITYPSAPLFLVYNTDLLKGMMNPIFYY
                     SESGQWKKPFPAHDVGTYPVANGQTYGGDMPVEESGNMLVLATAIAIVDGNADYAAQH
                     WEVLTTWANYLLKEGLDPKNQLCTDDFAGHFAHNTNLSIKAIMGVAGYGKLAEMLGKA
                     DIARQYTEVAREMAAKWVKMANDGDHYRLTFDKPGTWSQKYNLVWDRLLGLNIFPKEV
                     AATEMAYYKTKQNKYGLPLDNREDYTKSDWILWSACLTGSMEDFNALMVPVWNYANET
                     TSRVPLSDWHFTSDGTQRGFQARSVVGGYFMKMLEKKLGK"
     gene            complement(26196..27083)
                     /locus_tag="ACZPB4_05660"
     CDS             complement(26196..27083)
                     /locus_tag="ACZPB4_05660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007852063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIR1097742.1"
                     /translation="MLDIKTVYECNRCLGCKTLHPQVSLINLESPNLEQEAVKFEFYA
                     ILLIEDCPDGCYCCGRKYYDYSNATMAFLTPGEIFRMSENNTLPNKGYLLAFHPDLLF
                     HTSLDNPIKNYTFFAYHKEEALHLSQRETAKVTCCLENIEDELHHAIDTHSGTILSRH
                     IELLLDYCTRYYERQFITRENKNKAILEKLERLLDEYIISGKLENGQLPTAEYCTAEL
                     DLSVAYFNDLLRFETGKTLEEYFQFKRLSVAKTMLLKNGNTPALVARQLGYPNVQYFS
                     LIFKKITGIAPCEYPYAQN"
     gene            complement(27099..28016)
                     /locus_tag="ACZPB4_05665"
     CDS             complement(27099..28016)
                     /locus_tag="ACZPB4_05665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIR1097743.1"
                     /translation="MDKILNLDSVDLYNKLYGLETLNPLVSVIDLNKATSSVDLIRFN
                     YGIYALYLKLEKACDIKYGRQTYDYQEGTIVCFAPGQTAETNPTTDKVQVNAHGILFH
                     PDLLRGTSLGKNIKKYTFFSYEVNEALHLSEEERSIVMDCLKIIRMELEHGVDKHSKT
                     LLVNHIELLLNYCMRFYERQFITRGKTNRDVLTRFENLLDEYFESTLAEQDGLPTVKY
                     FADKLCLSSNYFGDMFKKETGKSPQEYIQEKVIELAKERISGTADTVSQIAYSLGFQY
                     PQHFCRLFKKRVGYTPSEYRAQIGLSTNL"
     gene            28250..29323
                     /locus_tag="ACZPB4_05670"
     CDS             28250..29323
                     /locus_tag="ACZPB4_05670"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HIR1097744.1"
                     /translation="MKKSLRELCTAIAICFCATGNLFATDNQINTDHTMDKNLNLIKE
                     WDKVFPQSDKVSHSKVTFRNRYGITLAADMYKPKHADGKLPAIAISGPFGAVKEQSSG
                     LYAQELAERGFLTIAFDPSYTGESGGEPRYVASPDINTEDFCAAVDFLSTRDDVDAEH
                     IGILGICGWGGMALNAAAIDTRIKATVTSTMYDMSRVNANGYFDAMDADARYELRKQL
                     NEQRTADTKNGSYALAGGLPDTLPDDAPQFLKDYYAYYKTKRGYHKRSLNSNGGWNKT
                     SALSFINMPILSYSDEIRSAVLIIHGEKAHSRYFSEDAFKKLKGDNKELLIIPGANHV
                     DLYDQMSVIPFDKIERFFVENFK"
     gene            29332..30198
                     /locus_tag="ACZPB4_05675"
     CDS             29332..30198
                     /locus_tag="ACZPB4_05675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3737 family protein"
                     /protein_id="HIR1097745.1"
                     /translation="MQQIKDMEFSGERPLFASHDLQLDNVVIHAGESALKECSNIIAI
                     GCRFEGKYPFWHVDGFTIKNSLFTEGGRAALWYSQNLVMTDTRVEAPKMFREMDGIRL
                     ENVQLPNAQETLWHCRNVELINVQIDHADYLFMHGENIKIRNYAQNGNYSFQYCKNVE
                     IRNAVINSKDAFWNTENVTIYDSEINGEYLGWHSKNLRLVNCKISGTQPLCYAHDLMM
                     ENCTMADDCDLAFEYSSVQATINSPIRSVKNPRTGSITAGSYGEVILDENIKAPGNCQ
                     LRLWNERTCFSA"
     gene            30204..31370
                     /locus_tag="ACZPB4_05680"
     CDS             30204..31370
                     /locus_tag="ACZPB4_05680"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HIR1097746.1"
                     /translation="MRYNFDEIVPRTGTNSYKWDSAVDTDVLPMWVADMDFRTAPVII
                     ETLRQRVEHGIFGYTRVPDAYYEAVTGWFERRHGWQIRKEWMICTSGVVPAISAVIKA
                     LTEPGDKVLVQTPVYNCFFSSIRNNGCEIIRTPLSYAHDTFTIDYEDLEKKAADPKVK
                     VMLLCNPHNPAGRVWTREELSRIGKICIRNGLIVVSDEIHCELVFPGYTFTPFASISE
                     EFLRHSVTCLSPSKAFNIAGLQIANIVCYDENLRRKIDRAININEVCDVNPFGVIATI
                     AAYNEGEEWLSQLIDYLWQNYLYMKDFCGKYLPDFPITLLEGTYLVWMDCRKLGKSSE
                     ELEHLLIEKAKLWLNAGTMYGAEGEGFMRWNIACPRSSLIKGVELFRDFVGCAC"
     gene            complement(31461..34571)
                     /gene="lacZ"
                     /locus_tag="ACZPB4_05685"
                     /gene_synonym="bga2A"
     CDS             complement(31461..34571)
                     /gene="lacZ"
                     /locus_tag="ACZPB4_05685"
                     /gene_synonym="bga2A"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004565 - beta-galactosidase activity
                     [Evidence IEA];
                     GO_process: GO:0005990 - lactose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase, LacZ type"
                     /protein_id="HIR1097747.1"
                     /translation="MKRQLMTGLFAALAFTAVAQSNEWRDPEVNAVNRAPMHANFFAY
                     ETAEVAAKDAKEQSQNFMTLNGPWKFFWVKNADARPTDFWRTDYNDKGWNNMPVPGVW
                     ELNGYGDPLYVNVGYAWREQFKNNPPEVPTVNNHVGSYRREIMVPASWNGKEIIAHFG
                     SVTSNMYLWVNGKYVGYSEDSKLEAEFNLTPYLKPGQKNLIAFQVFRWCDGTYLEDQD
                     FFRYSGVGRDCYLYARNPKQQIADIRVTPDLDAQYQNGSLAVNLTMKGKGTVELELLD
                     AQNKAVTTQSLNASGKVSTTIEVSSPHKWTAETPYLYTLRATLKEGGKTIEVIPVKVG
                     FRKIELKNAQILVNGQPVLFKGADRHEMDPDGGYVVSRERMIQDIQIMKKFNLNAVRT
                     CHYPDDNFWYDLCDKYGIYVVAEANIESHGMGYGEETLAKNPSYKKAHLERNQRNVQR
                     GFNHPSIIFWSLGNEAGYGPNFEAAYDWIKNEDPSRAVQYEQAGKNGKTDIFCPMYYN
                     YEDCAKYSEDNSMQKPLIQCEYAHAMGNSQGGFKEYWDLIRKYPKYQGGFIWDFVDQS
                     VRWTGKNGKMIYAYGGDFNKFDASDNNFCDNGLISPDRVPNPHMYEVGYYYQDIWTTP
                     GDLSKGEIKVYNENFFRDLSAYYLEWEMLKGGKVVRSGRVDDLKVAPQQTSTIRLDLG
                     ETCQCTEWLLNVSYKLKNREGLLPAGHTVAKDQLTLNPYKAPSMDLKNVETTNIETKA
                     PAVQDNDANYLIVEGCGFRTEFNRENGYLIKYEVNGQDMIKEGEALTPNFWRAPTDND
                     FGAGLQKKYAAWKNPEMKLTSLNQRMENKQVIVEAVYDMPTVSAKLNLTYVINNKGAI
                     KVTQKMTADKNAKVSPMFRFGMQMPMPRYFENIEYYGRGPVENYIDRKGNADLAIYRQ
                     TVDEQFYSYIRPQENGTKSDIRWWKMLNEAGNGIEVVASAPFSASALHYTIESLDDGA
                     RKDQRHSPEVEEADLTNLCLDKVQMGLGCVNSWGTIALPEYQIPYGDYEFTFILTPVK
                     HSIEIE"
     gene            complement(34584..35741)
                     /locus_tag="ACZPB4_05690"
     CDS             complement(34584..35741)
                     /locus_tag="ACZPB4_05690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HIR1097748.1"
                     /translation="MKQNILALYLIKLSKWFSLVMPIIVLFYEDHGLGLQDVFILKSV
                     YSVAAVTLEIPSGYLADVWGRKKCLILGCILFFGGYLCYSFTSTFTAFLFAEILLGTG
                     QTLVNGADSALLYDTTVRYKKEELYLRYEGRITMIGNFAEAIAGIFGGLLAAYSLRLP
                     FYAQAFVAFIGIPAAFALQEFNTKSKVQNPVSEILRILKYSLVTNRKLCYNIMFSGII
                     GAATLTMAWFVQPVLMKLETPTSYYGVIWTVLNLTVGLSALYSDQVERYFGMRKSNTF
                     ILLIIVGGYISLAYNLTYWGLAILFIFYIVRGFATPILKGYINQMTFSEMRATVLSIR
                     NFVIRLIFAAIAPFIGWLNDFYSLRVALLVSAGIIAIPGILFLVLQFRKAD"
     gene            35856..36260
                     /locus_tag="ACZPB4_05695"
     CDS             35856..36260
                     /locus_tag="ACZPB4_05695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HsmA family protein"
                     /protein_id="HIR1097749.1"
                     /translation="MVFNQLDIHLLITAICVISSALICYTIGVWGERFQGQLKAWHLW
                     FFVLGLYADAIGTGLMEHIAQLTHLHDTVHTVTGIIAICLMLIHAIWAIWTYFKGSLK
                     AKQHFNRFSIVVWFIWLIPYCIGIYMGMSLHK"
     gene            36340..36897
                     /locus_tag="ACZPB4_05700"
                     /pseudo
     CDS             36340..36897
                     /locus_tag="ACZPB4_05700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007218681.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004130 - cytochrome-c peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome-c peroxidase"
     gene            36970..38709
                     /locus_tag="ACZPB4_05705"
     CDS             36970..38709
                     /locus_tag="ACZPB4_05705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016266919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinone-dependent pyruvate dehydrogenase"
                     /protein_id="HIR1097750.1"
                     /translation="MAKKVADQLVDTLEKAGVRRIYAVTGDSLNEVNEAVRKNGRLRW
                     IHVRHEETGAYAAAAEAQLTGELACCAGSSGPGHVHLINGLYDAQRSGARVLAIASTI
                     PSREFGTEYFQETNTIKLFDDCSYYNQVATTPEQFPRMLQGAMQAAISSCGVGVIGLP
                     GDLAAENATAGLSSTFSFPTRQRVCPAEQEIRELADLLNNAKKVTLYCGIGAKDALPE
                     LVQLAKLLNAPVAYSFKGKMEIQYDNPNEVGMTGLLGMPSGYYSMHEAEVLVLLGTDF
                     PYEAFMPESNTIVQVDINPNRLGRRAKIQLGLCGDVKDTLDELIPLIHQKEDDSFLRE
                     QLAKYEKVRENLRSAAAVRGKEEKIQPEYVISVVDELSSDDAIFTVDTGMTCVWGARY
                     LQATGMRKMLGSFNHGSMANAMPQAIGAALAYPGRQVVALCGDGGISMLLGDLATIVQ
                     YHLPIKLIVFNNRSLGMVKLEMEVAGLPDWQTTMLNPDFARVALSMGMAGYNVINPDD
                     VFPTLQKVFNADGPALVNIMTDPNALAMPPKIEFSQMLGFAQTMYKLMMEGRSKEVLD
                     TIDTNLKHWKDVF"
     gene            complement(38714..39817)
                     /locus_tag="ACZPB4_05710"
     CDS             complement(38714..39817)
                     /locus_tag="ACZPB4_05710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family protein"
                     /protein_id="HIR1097751.1"
                     /translation="MNIHKITRYLLMLCAFTFLTLTAKGQDGEPLRLAVAGVSHGHLW
                     EVISRLDRGDFKIVGVAEKDDYLREHNGLRDKLDPNLFYADLGEMLDKTHPEAVIVYE
                     PIHDHLRVVEACAPRGIHVMVEKPLAVNNEHATRMASLAREKNILLLTNYETTWYNTN
                     HEAFRLIDSGAIGKIDRINVYDGHQGPFEINCGKEFTDWLTDPMLNGGGAVIDFGCYG
                     ANLATRLMKDEKPLSVYAVLRQNKPNLYPKVDDDATIIVEYPSATVQIMGSWCWPMGR
                     KDMHIYGDKGYIYQDTPKEMRIYTNGKERQEIAPSLNAPYNDSFYFLKAAVRKEIDVP
                     PTDLSSLENNLMVVRILDAAIQSAKSKAVIQLF"
     gene            39926..41407
                     /gene="proS"
                     /locus_tag="ACZPB4_05715"
     CDS             39926..41407
                     /gene="proS"
                     /locus_tag="ACZPB4_05715"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010537985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HIR1097752.1"
                     /translation="MAKELKELTPRSVNYSQWYQDLVIKADLAENSAVRGCMVIKPYG
                     YAIWEKMQRILDDMFKETGHVNAYFPLLIPKSFLSKEAEHVEGFAKECAVVTHYRLKT
                     NHDGTGVVVDPAAKLEEELIIRPTSETIIWNTYRNWIQSYRDLPILCNQWANVMRWEM
                     RTRLFLRTAEFLWQEGHTAHATREEAEIEAKKMQEVYANFAENYMAMPVIKGVKSESE
                     RFAGALDTYTIEAMMQDGKALQAGTSHFLGQNFGKAFDVTFIDKNGKSDYAWATSWGV
                     STRLIGALIMSHSDDNGLVLPPHLAPIQVVIVPIYRSAEQLAQISEKVAGIVAKLKAL
                     GISVKYDDADNKKPGWKFAEYELKGVPVRLAMGGRDLENNTIEVMRRDTLEKETITCD
                     GIEEYVKNLLEEIQANIFKKAYDHREANIINVDTYEEFKEKIEDGVFIMAHWDGTPET
                     EELIKNETKATIRCIPLAGDKTPGKCMVTGKPSACRVLFARAY"
     gene            41474..42601
                     /locus_tag="ACZPB4_05720"
     CDS             41474..42601
                     /locus_tag="ACZPB4_05720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HIR1097753.1"
                     /translation="MSYHEFILVVNFSSIIILVLLAMLLLIATRFRGESGYAAAIIVL
                     PNIPVYIYNMSRMLGWHDITLFFFPISYSVNTLLMPLLWLFTRRNFDLDPRFKPVQLL
                     HFLPAIVCVVIVLSIPMRKRMESILHEVTGDDTWIGDFNAAVITSQMIGYFVAIFIYL
                     YRKKQYIKDNWSDAEYMQKEWIPKLMILFAALFVTVMTCYAIWPRTDAWLIQILNVMA
                     MSFLVYNFIAHPTVPYIQGTSRMLVKDETVGFQSIPDEEQMRDICSQVKEYLETTNAF
                     LRKDLSLSILSRETGIYQKLLSRSINEYLKQNFFELINEMRVGEAKRRLLLPENAGHT
                     VDSLYEECGFRTRSTFFLAFKKVEGLSPAQWLNSVKKHTDQ"
     gene            43159..>45001
                     /locus_tag="ACZPB4_05725"
     CDS             43159..>45001
                     /locus_tag="ACZPB4_05725"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat-containing sensor
                     histidine kinase"
                     /protein_id="HIR1097754.1"
                     /translation="MWILSLIPSCHREGEVGLSQNDQVGIDSVVSACPDIDSLQSCLR
                     YFERTANELGVILAYKELEVRYREAARFNEAIGCHREGLRLAMQRKDTSEVIQALNNI
                     GTNFRRLGIMDEASNYHYRALSLCERLGDKESYKARKNRTISLSGIGNVYLTLENCEM
                     ADSIFRIALEEERTLDSDLGLAMNYANLGSIFEMRGMMDSAFVYYNYSMEHNRAAGSV
                     VGISLCHNHIGRLFEKKGQWDQAIREYRNAYDLMVADNDLYHWLESCLALARVNIYKG
                     DLRMAEAFLEHAEGAAKVPRAWKHLSSVYHLDYLRYKKLGDYKNALNAYTSSLAYADS
                     MRNTENMNHIQNLRVDYEKERSNRKLSLIQKNYEMGQRTKNIFLIACLIVLFLTVVAM
                     GFLWYALRMKSRNQQVMRRMEEVRANFFTNVTHEFRTPLTVILGVSEELRKGGIGEEE
                     LKTGLNMIGRQGKNLLELVNQLLEVAKVRSEIGDPEWRTGDIVAYTSMIVEDNRAYAR
                     QGQVDLCFTPSETIISMDFVPEYFRRIMDNLLRNAIKFTPRGGRVVVTMECVGSMLVT
                     HVADTGCGIAEEDLPHIFKAFYLGETGGAGTMGTGIGLSLVRQMVRSM"
BASE COUNT        11710 a         9683 c        11332 g        12276 t
ORIGIN      
        1 cgctctgagg atgtcttgag ggaaatcgtg actcgttccc ctttattgat acaggccgct
       61 atattggcga tagcgatttt cattgttgtt cagtttaaga gcgcgggagt gcagccgttt
      121 atttatttcc aattttaaga gtgacaaaca cgtatatcgg catagcctca cgccagtata
      181 ggcacaaccc tacaccacta gtgccgtaag gctacaccga tactgatttc ataggcaaag
      241 tatcttaggt tcactggcga agtatcttag gatcgtcggc cgatgcacct aagatatttt
      301 tttgacatct tagagtgttc ctatcatttc cggaaaaaca tgtacatgag tttctagaaa
      361 cactctgagg gttgtgagcc gacgggaagt ttgatgatga tattcttcaa atccgccccg
      421 gatacatttt ggaatacgct tagcccaaac tccggtatta ccgcaagtac atggtcgaat
      481 atatccgctt gaattccttc atattcgacc cataccttat tggatgagaa gcaataaagt
      541 tcgatgggaa tacctgtatc agtcggttgt agatgcctta ccatgcagac taattcctta
      601 cttacttccg ggaggcttct taggtaacgt acgagataag cacggaagac tcccagattt
      661 gtctgtctac gtccgttcac ccaaatggaa ctatcgatat gatgttcttc attgtattca
      721 tctaattcct gttcttttcc atcgatgtaa tccgtgataa gagagatctt acgaaatttc
      781 tctagcattt ccggggtaca aaaatgtacg ctgttcatat cgatattgat agagcgcttg
      841 atacggcggc ccggggattc gctcatacct ctccagtttt ggaaagcgtc gcttactaag
      901 gcgtaaggag ggatggtcgt gatggtattg tcaaagtttc ttactttcac ggcgttcaat
      961 gtcacctcga taaccgtgcc gtccgcacca tatttgctca tcgtgatcca gtctccggcc
     1021 cggagcatat cattggcgga taattggatg ccggcaacga aacctaagat cgtatcctta
     1081 aagaccaaca tcaagatagc cgcagacgca cccaatccgg ccagtaaaga aaccggggat
     1141 ttattgataa gaatactgat aatcaatatc actccaataa agaaaaccgt aacctgcaag
     1201 atctgtatga agccttttaa cggcttgttc ttaaaggaat cttttttatt atagatctcg
     1261 tggatcagat ttaaggaagc gtttataaac cttaaagaaa ccgctatgat ataaatctga
     1321 caaagttttt ggagtactat taaaatcttc ggtgtctctt cggctgagaa ggcgaatggt
     1381 aacaatatat aaatcaatat ggccgggatc atatgcatca tcttattaat gatcttacga
     1441 tccacgatta aatcgtccag ttgatttttc gtcttcctcg ctaatcgttt gaacatacct
     1501 aggaaaatat accggcaact ataatcgatc ccaacggtga cggctataat aagtaataag
     1561 atcactatat tgtctaggta actggaattt tcgcttatca accccatttg aactaataaa
     1621 ttatataccc attcttgtat cttgctcata aatacgattt taaactttaa gtagacaatc
     1681 cggagacgaa gataggaaaa ataatccgaa cacgtacttt agtctgaata ttgatatact
     1741 ttcaattcaa atttaggaat catagcgaag aaatggtcga atatatccga ctggatccgt
     1801 tcatattctt tccatatttt attccgggag aagaaataaa tctggacggg aacaccatat
     1861 tccgtggatt gaagttggct gataattaaa tccaaatctt gatttacgac aggaagactt
     1921 gtcagataac gctctacata tacacggaat acttgggagt ttgtaggtac tacatcctta
     1981 tccggttggt aatccgctaa taaaggaatt tccttgcgga aggtatctag catctccggc
     2041 gtacagaact tgatcgtatt caaatcgaga taaatggact tcataaccct gcgtcctcca
     2101 gactcaacca tcccgcgcca gttttggaaa gaactattca ctagattata aggcgggatt
     2161 gtcgagatcg tattatcgaa gttctgaact ttcacggtgt ttagggttat ttcttgaaca
     2221 ataccgttcg cattggcaga aggcatcgtg atccagtcgc cggggcgcaa catatcattt
     2281 gccgaaagct gtatacctgc cacgaaacct aatatgctat ctttaaagac caacataaga
     2341 atagctgccg atgcacctaa tccggcgaaa agggtagccg gggatttatt gacgagaatc
     2401 gctataatga caatgccgcc aacgaagaaa acaagcactt gtaatacttg tataaaacct
     2461 ttcatcggcc tgtttttcat tttctcctgt tggttaaaca aatccagcat cattaagaga
     2521 agaccgttga gcgctaacag cagggaaaat atgatataga tcgcgcaaat cttctgggaa
     2581 atgaataata attcctttcc tcggataaaa gccatcggga gcaaaacata tactaaaatg
     2641 ccgggaatcg tatgtacgag ataatgtacg accttacgtt taattaataa cgtatcccat
     2701 ttataatgcg tatgcttaac gatactacgt acccctccga caaaaatagc ttggcataaa
     2761 taatctaatc cgatagcgac cgccactagt aagatggcga tgatcgcctc gtcaaatgtg
     2821 ttcgctattt tctcgtctac accccatccg gtgaggactt tgttcatcca actacctaaa
     2881 tttatcataa taatcgtttt ttgatataac actactctta aaaataggtt caatcctacg
     2941 ttaaatttgc ccttttgtta agattgcttg taaatgtaag cgtattaatc caattgaaaa
     3001 atgtatcttt gtgaaataat ataaacttaa atggattcca tgagatctct gttgtcaacc
     3061 tcagattttc tacaggtacg agagcataaa ttaagtaatg atttgacggt atggttgaat
     3121 gaggaccata gccaacctaa gatattcgga gccgtagtcg taaaagccgg agctaaagat
     3181 tccccaaaca caggtattgc gcattatttc gagcatatga tgtttaaagg aacggataag
     3241 atcgggacga tcgactatga gtccgagaaa gtcttgctgg acattatcgc cgagaaatat
     3301 gacgctttgg cggataccga ggatcccaag atgcgtgccc atttgcagca aatcattaac
     3361 gacctgagcg tacgtgccgc tgagtatgta ataccgaatg agttcgaccg gttgatctct
     3421 cgtttcggtg gtacgaagtt gaatgccggg acttcttacg actatacatt atatttcaat
     3481 acattctctc cgcaatatat ctcccaatgg gccgagatca atagtgagcg tttggtaaat
     3541 cccgtatttc gtcttttcca gagtgagctg gagacggtct atgaggaaaa gaacatgtat
     3601 ggagatacga tggctagtgt cgccatcgag aaattgacag agcgttattt ctatccgcat
     3661 ccgtatgctt atccgattat cggaagtgcg gagaacttga agaatccccg tctttcggag
     3721 atgcgccggt tcttcgagaa atactatgtc gcttccaata tgggattgat cttaagcggg
     3781 gatttcgata cggaggaggt cttgccaatc ttggaatcta ctttttcacg gatacgaaaa
     3841 gggaagccgc ctcaccggga tattgttaca ttaccgccat tcaagggacg ggagaaggtg
     3901 agcgtacgta ttcctatgcc tttcgtgaaa attatggcat tgggattccg gggagttccc
     3961 gcaaatcatc cggatcaagt tgcgctcaat atcgccgtat ctttattgaa taactccaat
     4021 ggtacgggat ttttggataa gctgacggta gatcataagg tgatgggtgc gatggcggtt
     4081 aaccaaagta tgaatgaggc aggaatatta ggcttgttgg tatttccgaa gttctttttc
     4141 cagacctatg cggcagccga gaaattagta tggaaacaaa tcaaccgcat taaggagggg
     4201 gattttagcg atgagatgtt tcaaagcttg aaattggaac agaaacgcga atatgcctcc
     4261 aaattggaag acataaactc aagggccgag gtgatgatgc gtattttctc tcaagggaaa
     4321 agctggcagg attatttgga tgaggtcacc cgtatcgatg ccttgtcgag agaagacgtg
     4381 attgagatcg ccaagaaata ttttacggag aattatatgt acgtcacgaa gaagaccgga
     4441 cgctatccga aaacgatctt gcccaagccg gattattcac cgattatacc gaagaactcc
     4501 gatgcttcct ccgcttatgt ggaacgtttg gaaaagatac ccgtacaaga attgaaaccg
     4561 cattttctcg attttgagaa agacgccgag gtcgtatctt tgcgtccgct tgtcacgttg
     4621 tataagactc ataattccgt aaatgatata ttctcgctga cactatctta tggagtgggg
     4681 cagttggagc ttcgtgatct tgataaattg tccgcttatc tacctttcgt agcgacggag
     4741 tcgatgtctt ttgaggtctt tcggggtaaa ttgcaggaac ttggtagtac attgactttt
     4801 gattccacgg attctgagtt tctggtggtg gtgaatggtt ttgatgggca ttttacccaa
     4861 acaatggctt tggtcggcga tttcttgcgg cacgccaagc cagatgacaa gaagttacgg
     4921 cagattgtgg acgaggcgaa ggtaacggag aaatcgttgt tcaattccag cgagaacgta
     4981 gccgatatgc tgttagagaa agtcaaattt ggggagcaat cccgttattt gactaaatta
     5041 tcgttcgctg aaatcaagaa actaaaagga aagatgttgc tggacacttt cagtaaggta
     5101 cgttcggtcg cttgtaacct gcattattgt ggtacattgt ctatggagga ggctgcccgg
     5161 cagatcaagc agcatttacc cttggaggag gtaagtattc catcgaactc tccctatatc
     5221 cgtgatctta tgacgtatga taagccgact gtctttttca tggacatgga ggatgtcacg
     5281 caaagcataa tctatgccta tatgtatatc gatccgttga aggctaagga agatcgtcct
     5341 atttcccggt tgtttagtgc ttatttcgga ggggatatgt catccttgat gtttcaggag
     5401 atccgtgagt ttcgttcgtt cgcttatcaa gtaaatgccc gtttgaaaca tcctcctttg
     5461 aatcgatcgg agaagcccgc tagtttcgtg atgaaattgg ctacacagac ggataagatg
     5521 atcgatgcga tggaagtgtt ggagaatttg gtgcatgata tgccggaacg tccggaacgg
     5581 gtggagtcgg tgaagcagac gattcgtaat tgggtgaata atgaatatcc tactagtcgc
     5641 tccctttcct tgaagatcgc cggtttccgg cgtgaagggt acgagagcga tccgaacaag
     5701 gattatctgg aggttatcga tcggatgact atggaggata tccttcgttt ttatagggag
     5761 aatatacaag atcatttaat gatatatgcg atagtcggta attcaaagag tatggatatg
     5821 gagaaactct ctaaattcgg acagatcgtt aaggtaacaa agaaagacat ttataggtaa
     5881 tgtatagtaa ggaggaactg aagaatctca aattggagtt ttgggaaagc ttcgccgctt
     5941 tttgtgaggt gcaaccctat ttgcgggggc gtaagaaaat ttggacatta tatgatacga
     6001 aggtaaaggg cgttgagttg aaattcgacg cgaaccgcca aggggcttac gttattcttg
     6061 aggtaaacca ccgtagcgag gatttacgtc tggaaatgtt tgagcgcctg acttggtata
     6121 aagagacgtt ggaacaggat tttcccgaag gtttgatctg ggatatttgt tttgtccgtg
     6181 agaatggccg acaagtggcc cgtatctatg tagcaaaaga aggattggat ttgcatcgga
     6241 gagcgcattg gggagatttt ttcactttta tggctagcca gatgtatttg ttggaacgaa
     6301 attttatggg tatagcagaa tacttaagag aataattacg agatatgaat ctaaaggtat
     6361 ttatcggagc ttgcgtactg tccggtctgg ttgcttgtag ctctgttaaa caagatgagg
     6421 ccggtttgtc ccggcccggt gtgagccttg agctagctca attccggaag gagcatttct
     6481 caaatgtccg ttataatctt ttcttctcga tcccggaatc tcgtgacgag gcgatccggg
     6541 gaaaagtgga gctatccttg cgattagacg agaaacagcc gcttattatt gatttccgcg
     6601 gagaaccgga gcaagtgacc tccgtaacct tgaacggagg agatatttcc tatgaagtga
     6661 aagatgagca tatcgtgatt gcctcagatt gggtagcggt gggagagaac cgggtagcga
     6721 tcacttttac tccggcggat caatccttga atcgacggga tgagttcctg tatacgttat
     6781 tggttccgga ccgggcacgt acggtattcc cttgttttga ccagccggat atgaagtcgt
     6841 tttttacctt gaccttggaa gttccttcca cttggcaggc tgtggcgaat ggcgctatca
     6901 cacaaacgga tagtacgagc gtctccggtc ggaatcgtat ttctttcaag gagacggaac
     6961 cgcttagtac ctacctgttc tcattcgtgg ccggtaaact gactcgggag gtttattccc
     7021 ggaacgggcg ggatatctct atttatcatc gggagacgga tccgaaaaag atcgctcaat
     7081 gcccagccat cgccgacgag gtgttcgatg cgttggaatg gcaggaagac tttactggta
     7141 ttccttatcc tttcgctaaa tatgacgtga ttatcttacc cggtttccaa tatgggggta
     7201 tggaacatac gggtgctact ttatatacgg atcgccggat gtttctggat gagcatccta
     7261 ccttaaatga gcgattgagt cggagttcct tgatcgcaca tgaaacctct catatgtggt
     7321 ttggcgatta tgtaacgatg aaatggtttg atgatgtatg gacaaaagag gttttcgcta
     7381 attattttgc ttcccgtatc gtagaacctt tatatccgga cgtgaatcac cggttgaatt
     7441 ttattcggga ttatattccc gcatcttatt cggaagaccg tacgtcaggt gcgaatccga
     7501 tcaagcaaga tttggataat ttgcggaacg ccggtttggt atatggtaat atcatctatg
     7561 ataaatctcc cgtggttatg gaaatgttgg tacgtgttct gggagaagag gctttccagc
     7621 agggaatccg tgagtacttg actacttatg cgtatgggaa cgctacgtgg gagggcttga
     7681 tccgtatctt gaataaatat acggaagagg atctggccgc ttggagtgag gtgtgggtga
     7741 atcagaaggg tatgccggag attacggctt cggttaagga cggcgagttg gtcgtagagc
     7801 agcgtgatcc gttgggccgg ggtttaaaat ggccgcaaga attaacctat cgggtgatct
     7861 gtggaacgga ttcggaagaa atcccggttt ctctcgaagg aaactctgat tccttccgaa
     7921 tgaaattaag ttttcttccg aatggaaatt gtgtcattct tccgaataca aatgggcgtg
     7981 gctatggctt ctttaaaata acagaggggg agtcttccgg tctatggtct gtgcttcgct
     8041 tatcggaaga tgaggtgttg aagggatctt tgctgattac cctttatgag aatcttcgtt
     8101 ggaaaacgat ttctccacaa gggttccgtg atgaaatgtt agcgtattta ccgaatgagt
     8161 ctaattcttt attgttctcg atggctttaa gctatttagg agattgccag cggatattcc
     8221 cgtcggattc tcgtccgttg gaacaggcct tgtggaagat cgtgacaacg aatcccgtat
     8281 cccaacatcg tttgcaggcg tttcgtttgt atcgttcgat agcggattcg gaggaggcgg
     8341 tacaacgcct gtatacgtta tggcaggaac ggaaagctcc gaaagattgt gcgttgagcg
     8401 agagtgatta tattggcttg tcctatatat tggcgataca tttgccggaa aaagcggatg
     8461 agattatcgc tacgcaattg tcccgcatac agaatccgga ccggaagaag gagtatcaat
     8521 ttatctcccc atccgtatcg ccccgtaaag aggaacgtga cagtgtcttc gcttccttgt
     8581 tgatcgccgg gaatcgtagg gtggagccat gggcctcttc cgctctcgct aatttgaacc
     8641 atcgcctacg agaacaagag tcggtcgctt atatccgtcc ggccttggaa gcgatgccgg
     8701 aagtacagcg gactggcgat atctttttcc ccaccgcttg ggttcgctcc ttgctttccg
     8761 cccatacatc gaaggaagct cgggaagaag ttgatgcgtt ttttaccgcg catccggact
     8821 tccccttgat gctttccaat aagattaagc agcaagcgag tcatttgtat taaagtaaat
     8881 cattatattt gtccttgaga acgaattaat aagaaaggag catttgtatg acggcaatgg
     8941 aactaaaatg cctaaagatg gatttggtcg aagaattgtt aagcatcgat gagacagaga
     9001 tcaacttgct ctaacatcta cgacaaagca gaacgtgaat ctataagctt gaaagagata
     9061 gaagagttgc ttcgtaagaa cggattgaag taatatcgat attgtgataa tattttgtca
     9121 gaaatatttg ttctttcaat tattattgta actttgcgac gtaaataaca aaagaaatga
     9181 aaataacgac tacattatat caccatcatc attacagcgg gcaatagttc ggtgggctga
     9241 atggtatgta tgtactcatg ataaaaagat aaaggcttgc cgttttgcgg taagcctttt
     9301 tttgttgata tttataatat aaaaataaga tatagttatg ttgagaattg cggtacaatc
     9361 gaaaggccgt ctgtacgacg agaccatgat gttgcttgaa gaagcaggta ttaaactaaa
     9421 caggggcaaa cgcatcctgt tattatcggc aaaaggtttt ccggtagagg tattattcct
     9481 tcgtgatgat gatattcctc agtctgtagc taacggtgtg gcggatattg gtattgtcgg
     9541 agagaacgag tacgtagaga aagggcaaga ggcgaaattg atcaagcgtc tgggctttag
     9601 taagtgccgt ctatccttag cgatccccaa agatgaggaa tataaggggg ctgagtggtt
     9661 tgagggaaaa acgatcgcta cttcctatcc tgcgatccta cggtctttct tggaggagag
     9721 aggcgtgaag gcggatattc atgtaatcag cggctctgtg gaaatcgccc cgggcattgg
     9781 tttggcggac gctatctttg atatcgtaag ctccggtagt actttggtaa gcaatcaatt
     9841 gagagaagtg gaggtagtcc ttccttgtga ggctttattg atcgccaaca ataatctgtc
     9901 caaagagaaa ctggagatct tggatgagct tctattccgc tttgaagcga ttcaagtcgc
     9961 cgagggcaag aagtacgtgt tgctgaacgc tccgaaagaa aagctggatg agattatcga
    10021 ggtgcttccc ggtatgaaga gcccgaccat aacgcctttg gcaaacgatg aatgggtctc
    10081 tgttcaatcc gtgatcgccg agaagcattt ctgggaaatt attggtaaac taaaatcatt
    10141 gggggctgaa ggtatcttag tgcttccgat cgagaaaatg attgtataat atggagatta
    10201 taaaatatcc cggacgtgag gaatggagct cactaatcaa acgtcccgca ttagatgtaa
    10261 ccaccttgtt cgatacggtc cgtacggtat tggacgaggt acgcgagcag ggtgacactg
    10321 ccgtaaaagc gtatgaggaa aagtttgata aggtgcagct ttcttccctt caagtctcgg
    10381 aagaggagat gcgggaagcg gatgccttgg tcgctgagga cttgaaacag gcgatccgta
    10441 cggcaaaggc gaatatcgag aagttccatg cctcgcagcg tttcgaggga aagaaagtgg
    10501 agactacccc gggagtcact tgttggcaga aagcggtagc gattgagaaa gtcggtttat
    10561 atattccggg cggaacggcg cctttgtttt ccacggtatt gatgttggca gtgcccgcac
    10621 gtatcgccgg ctgcaaggag atcgtattat gtacgccacc gaaccgggaa gggaaagtac
    10681 atcccgctat cctgttcgcc gcagaggtcg caggtgtaag taagatattc aaggctggag
    10741 gaatccaagc gatagcggcg atggcctatg ggacggaatc ggtccccaag gtgtataaga
    10801 tctttggccc cggtaatcaa tacgtgacgg cggcaaagca attagtaagc ctgaaagagg
    10861 tcgccattga tatgcccgcc ggaccatccg aggtagaggt gatcgcggac gagacggcga
    10921 atcccgattt tatcgccgcc gatttcctct cgcaggccga gcatggagtg gatagccaag
    10981 cgatcctcgt aaccgcttcg gaaacgatcg tggaacccgt ggcccgtgcc atccaagagc
    11041 aactcgatcg tttgcctcga aaggaaatta ccgagaaatc attagcgcac agccgtatca
    11101 tcgtattgaa agattcgcag gaagtcgtag acttcacgaa ccaatacgct cccgaacact
    11161 tgattatcca gacggcggat tacaccgcta tcgcggagcg aatcgagaac gccggcagtg
    11221 tctttatggg tccatatact ccggaaagcg caggcgatta tgcttccggc acgaatcata
    11281 ccttgccgac caacggctat gccaaggcat atagcggcgt gaacttggat agtttcatca
    11341 agaagatcac tttccaagag atcacttccg atggtatccg tgccttgggt agcacgatcc
    11401 aaaccatggc ggccaacgag catctggatg ctcaccgcaa cgcagtaaca attagattga
    11461 acacgatatg aaagacctga aagatttagt aagaccgaat gtctggaatt tgaaaccgta
    11521 ttcatccgca cgtgatgagt ttcatgggga tgcctccgtt tttctggacg cgaatgagaa
    11581 tccgtggaat gtgccgtata accgttatcc cgatcccttg cagtggaaat tgaaggatcg
    11641 tctggccgta ctgaaaggcg tggatcgtag ctcgatcttc ttgggcaatg gcagcgacga
    11701 ggctatcgat ctggtgatcc gtgccttttg cgagccgggg ttggatagtg tggtgacgat
    11761 ctcgccgtcg tatggtatgt atgaggtggc tgcggatgta aataacgtgg aatgccgcaa
    11821 ggtctctttg gacgagaatt tcgacttgga cgctgaccga gtgttggaat cggcggacga
    11881 gtggactaaa gtgatcttcc tatgttcccc gaataacccc agtggcaata gcctggatcg
    11941 tggctcgatc tataagatat tgaagaatta tgaaggaatc gtggtgatcg atgaggctta
    12001 tatcgacttc tccgcttatc cctctttctt aaaggaatta tcgggattcc caaacctgat
    12061 cgttcttcaa accttgtcga aagcgtgggg agcggcgggt attcgtttgg gtatggcatt
    12121 tgcctctccg gagattatcg gtgtcttgaa taagatcaaa tatccgtata acgtcaacca
    12181 gcttacgcag gagaaagcgt tggagttctt gaacgacgag gcgaccatga agcaccaagt
    12241 gaacgagatc ctcacggagc gtaaccggct ggagaagatc ctgtccgagc ctcctttctc
    12301 ctatcaagta tatccctcag acgctaattt cttgttggtg aatgtcggca aggcggatgc
    12361 catgtataat gggctcgtga agaaagggat cgtagtgcgt aaccgtagca acgtgcagaa
    12421 atgccggggt tgccttcgta ttacgatcgg tacgccgaaa gagaatgata gcttattgaa
    12481 cgcgatgaaa aacatgaaat tatgagcacg aggaaaagag cgttgtttat cgatcgagac
    12541 ggcacgcttg taaaagagcc gcccgtagat tatcaattgg atagcttgga gaaactagag
    12601 tttgtcccga aggtgatgcg taacctctat ttcatttgcg agcggttgga tttcgagttc
    12661 gtgatggtct ccaaccaaga cgggctgggt acgccctctt tcccggagga gactttctgg
    12721 cctgcccata acttgatgct aaaaacgttg gaaggcgagg ggatcgtgtt tgatgatata
    12781 ttgatcgatc cttcctttcc cgaggataat tccccgaatc gtaagcctcg tacaggaatg
    12841 cttacgaaat atatgacagg tgaatacgat ctggagaata gtttcgtgat cggggatcgc
    12901 cttacggata tggagttggc ccataatctg ggcgctaaag gtatctggtt gcgcccggag
    12961 gagggagcgg agactgagtt ggcggcttac gctacttcat tgtctcccgc ctatatcacg
    13021 gatgattggg ataaaatcac cgagtatctg tttgctggcg agcgtcgtgc ggtcgtacgg
    13081 cgtgccacga aggagacgga tatttatgtg gactggaatc tggatggaac cggaaagaca
    13141 tcgatctcta ccgggcttgg tttcttcgat catatgttgg accagatcgg taagcattct
    13201 ggtacggacc tgacggtacg ggtaaaaggc gacttggaag tcgatgagca tcatacgata
    13261 gaggacacgg cgatcgccct tggcgaggcc atgctgaaag cgctgggtga taagcgaggg
    13321 atcgagcgtt atgggtattg ccttccgatg gacgactgct tgtgtagcgt ggcgctggat
    13381 ttcggtggcc gtccttggtt ggtttgggac gctgagttcc accgtgagaa agtaggggat
    13441 atgcctacgg agatgttcct ccatttcttc aagagcttga gcgacgctgc ccgcatgaat
    13501 ttgaatatcc gtgccgaggg tacgaacgag catcataaga tagaaggtat cttcaaggct
    13561 ttggcccgct cgatcaagat ggcgatccga cgagatattt atcggtttga gctaccgagt
    13621 acgaaagggc tcttgtaatc tgtaaaaaac actactgtat ttgtgcacga atacagtagt
    13681 gctttagtct gaatactatt gtgtttatcc acaaacactg tagtgttttt gactcagatt
    13741 ctatgacatc agataaaccg ataaaagcct atagaggata ttcctcgaaa gcatatagaa
    13801 ccgtggagag atacctttct cctgtgtccg gaagcaacgc cacgatcgtt tttccctcat
    13861 tctccggaag tttagctagt tccacggcgg cgtatacagc ggcgccggaa gatattccta
    13921 ccagcaaccc ttccttcccg gccagttccc ggctggtacg gatagcgtca tcgttcgtta
    13981 cttgcaggat cttgtcaact acctccccgt tgtaggtctt ggggataaag ccggctccga
    14041 tgccctgtat cttgtgcggg ccgggcttgc ctccggaaag taccggtgaa tcgctaggct
    14101 ctaccgctac gatttgtacg ttcgggttgt gagctttcaa tccggcaccg acaccgctga
    14161 ccgtgcctcc ggttcctacg ccggctacaa acagatcgac tttaccatcc gtatcacgcc
    14221 agatctcttc ggcggtcgta cggatatgta cggccgggtt agcgggattc tcgaattgtt
    14281 gtaggatgat ggaaccggga gtcgcgtcac gcagttcctc cgctttggcg atggctcctt
    14341 tcatgccttc cgccccgggg gtgaggacga gctgggcacc taacgctttc aataagttac
    14401 gacgctcggc actcatggta tccggcatgg tcaggattaa tttgtagcct ttcgaggcgg
    14461 agacaaaagc gagtccgact ccggtattac cgctggtcgg ttcgataatg gtagcgccgg
    14521 gtctcaacaa gcctttagcc tcggcgtcct cgatcatcgc caaggcgatg cggtctttta
    14581 cgctaccagc cgggttgaaa tattccagct tgccgattac ttgggcttta aggcccttgc
    14641 tcgcattgaa attagagaac tccaacaggg gagtgttgcc gacaaggtcg gtcagttgtc
    14701 ttgctattct tgccatatac aaatgaattt tgttgtttct ggattctttt atttatatga
    14761 caaagatagt ggatggattg tttacggcat ataccataaa ccgggtattt ttttacctcc
    14821 ttctatgcgt cacgcacaaa aggaggttac aatcataatt atatacaagt ctgaaaggac
    14881 tctctttaat gtctgcctcc tcctaaggct tggtagaggt ttacggtggc ttgaagctcg
    14941 tcaaaacgat ccgttacttg ggagagctgg gcgctgagca gggtttgctg tgccgtgagc
    15001 acttccaaat aagtagtgtt tccatgcgtc atcagcaatt gggtgctacg cacggcatct
    15061 tcaagcgatt cgatttggtg tgtacgcaag tcgatctttc cctttgcggt ctgggcttgg
    15121 gtaagtgcgt cgttcacctc ttttccggcg ttgagcacgg tttgttggaa agtgagcttg
    15181 gcctcctctt gctgcgcttt cgctattttc aattgggcga tattcgctcc tttgttaaat
    15241 agcggttgcg tgagggagcc gaccgccgat agtaatagtt tacccggatt tacgatgtaa
    15301 ctgcctgcgc tgtttgtcca ccctgcgctg ccgctaagac gtagcgaggg ataaaaattg
    15361 gagcgtgcgg aggctgtccc gtagaacgct tgcgccaatg cgtactcggc gctacgtaca
    15421 tccggacggt tcgatagcag ctgcaccggg atgccgatcg ccagatccgg ggtcaaggac
    15481 tgctcttcca atcttcctcg ctcgatatct tgaggtgttt ctcctaataa gacggcaagc
    15541 gtattctcgg tctcccggat ggtctgttcc agatccttaa cagaggtctc gatggagtag
    15601 caagtagcct cggtttgcga tacggccgcc tcggtagtca tgccggctgc cattaatgct
    15661 tgggtggcac gaaggctttc ttgccatttc acggcggttt ctgtcgtgat ctcgtattgc
    15721 cggtccagca tcaataaggt ataatataaa ttggcgatat tggcgatcag ttgtgtttgt
    15781 acggcttggc tatacgcttg gctttgcgac aaggcggctt tcgcttgtcg tttggcgttt
    15841 gtcagccggc cgaagatatc gacctcccaa ctggccgata ccgggacgtt gtatgtccac
    15901 gacgctttcg ccttatcaaa gctacttgtc gtgccctgtg gatctaggga gagcgacggg
    15961 aggtaggaga ggcgggaggt cattaacgcc gcctcagctt cttgtacctt tagatgggcg
    16021 atccgcagat ctgtattatt ggctaatccc cgttcgatca aggattgcaa ggccggatcg
    16081 gtgaataggt cccgccaact gatattcccg atggagaagg tatctgccgg ggctatctcc
    16141 tcccgatata gattctccgg gagggtggcg acaggctcgt atttcttgta aatgccgcag
    16201 ctgttcaacg ctagcgtcgc tacggcaaag agtatgatgt tattcttcat atacattata
    16261 tatatacaac tggatagatt atttcttgct atctaaatat tcttttcttt cttcggcggc
    16321 ctcttttacc tcttcttgca cctgccaatc aagggaacgc tcgaattgga tcgggcgtag
    16381 tttctcttgc aggtattgga acgtgatgaa taagcaaggc acgataaata acaaagccaa
    16441 tgtaccgatc aacataccgc caacggcacc ggttcccaac gagcggtttc cattagcgcc
    16501 tacgccgttg gaaacgatca atggcagcaa accgaatatc atcgtaagag cggtcatcaa
    16561 gatcgggcgc agacgaacct ttgccgcgct aagagcggct gaagtcaggc tcataccgga
    16621 caagcggcgc tgggtagcgt actccgtcaa taagatggcg gtcttcgcca acaatccgat
    16681 caacatgatc aaaccggttt gcagataaat gttattctcc aatcccatga acttagcgaa
    16741 caagaaacta cccatcaaac ccatcggtac ggaaagaatc acggcgaaag gaacaaggaa
    16801 actctcgtac aaggcactta ggatcaaata aatcatcaag atacagatac cgaagatgat
    16861 aatggtcgta ttactctgct ggttctcctc acgggtgata ctaccgaagt cgtagccata
    16921 cccttttggg agcgaagtgg ccgctgtctc ttttaccgcc ttgatagcat ccccggagct
    16981 atatccattg gccggtacgg cattgacggc gatcgaatta tacatgttga aacgggctaa
    17041 agattcggca ccgtatacct tggtcaaggt gataaactga ctaagcggtg ccatctcgcc
    17101 gttcgacatg cgtacgaacg tattattcaa ggaggcctca tccagacgat atttaggatc
    17161 ggactgtatc atcaccttat acaccttcga gaaacggttg atattcgaca catattgccc
    17221 tccgtaataa ccggaaaggg ttgatagaac agcatccgga gtgattccgg cccgtttgca
    17281 tttcgccgcg tccacatcca cgcgccattg cgggtacttg atatcgaagg tagagtaagc
    17341 cgtagcgatc tcgggccgtt cacgcaaggc ggcgagatat tgctgggtcg tgttaaagaa
    17401 ggtcgttaag tctccaccgg ccttgtcttg cgtatgcatt tccaatgcgt tacccatacc
    17461 atatccgggg atcatggccg gggcgatggc gaaaatcgta gcgtccttga tatctgccgt
    17521 acggccatat acctgtccga tcacggcttg tacgttatct tccttgtccg ggcgctcatc
    17581 ccaatgtttt agtttcaaga tgaacatacc gaaagagcta ccttgtccgg ccagcaaacc
    17641 ataaccggaa accttggaat aagattgaag ctgtggaatc tggttgatcc gttgctcgat
    17701 attcgtcatg atcttgttag tcgtagccaa agagcttccg gaggccgtac ttacgttgac
    17761 aaaaaccgta ccttgatcct catcgggcac caagctggat tttgtcgtgt tcatcaagac
    17821 gatcagtaat acgatggagc atgccaataa agaccaagcc agccatttcc gcttgataaa
    17881 gaacaacacc ccgtgcttat atttcttgat gaccgaatcg aacgcggcgt tgaacgcctt
    17941 acggaaacgt gcggcgaagt tattcttttg ggtgccgtcc tcgttgatgt aaggcttcaa
    18001 taagatagcg caaagcgccg ggcttaacgt taacgcgtta acggtagaga tacctacggc
    18061 cgctgccatc gtcaagccga actgcgtata gaacgtaccg gatgtaccgc tcatgaagga
    18121 taccggaata aacacgccca taaataccaa tgaagtagag acgatggcgg atgtcaatcc
    18181 tttcatcgcg tccatactag ccatataaga ggacttatat ccaacgtcga accgagcttg
    18241 gactgcctct acaacaacga tcgcatcatc caccaccgta ccgatcacca ataccaaagc
    18301 gaataaagtg atcaagttga tgctaaatcc ggcgaccgtc ataaaggcga acgtaccgat
    18361 caaggaaact acgatcgcta ccaacggaat cagcgtagaa cggatatcct gcaagaagac
    18421 atataccaca aggataacga ggataatggc ctctatcaag gtttttacaa cctcatggat
    18481 cgaggcgtac aagaaatcat tcgtactcat caattttacg acctcgatac ctttcgggaa
    18541 gtctttcgag gcttcctcaa gaaaagcgtc gatcttatta ttcacctccg tggcattcga
    18601 tccggctgtc tggaaaacca tacaggagat acccggctta ccgtttgttt gtccgatata
    18661 ggcataactc tcctttccta actcaatgtc cgctatctct tttagcttca atacctctcc
    18721 atcctcggtg gagcggatca cgatatcgcc gaattcctcc ggagtaagca ggcgtccgct
    18781 atatttcatg gtgtactgat acgtctcgtc cgagttctcg cctaaagaac ccgtggcgga
    18841 ctcaatattt tgctcggcca acacggaggt cacgtccgag gggatcaatt tgtattgggc
    18901 cataacgtcg ggcttcatcc agatacgcat actgtaatcg ccacccataa ccatcaactc
    18961 gccgactccg gagatacgga gtatctctgg ttttaggttg atgctgatgt aattacagag
    19021 gaagttctcg tcataagaac cgtccgagct atagagcgag aagatctgta acatactggt
    19081 ctggcgcttg gaagtcgtga cacccacttg ggtaacctcg gccggcaatt gcccggtcgc
    19141 tttcgataca cggttctgta cgtttacggc ggccatgtcc ggatcggttc cttgttggaa
    19201 atagatcgtg atcgtggcgg taccggagtt ggtagccgtg gaggtcatgt aggtcatatc
    19261 ttccacgccg ttgatcgcct cttccaaagg ggctacgaca ctcttctgca tggtctcggc
    19321 attcgccccg aagtaagtcg tactgaccat aacggtagga ggggcgatat ccggatattg
    19381 ttctacgggc aaggtgaaaa gcccgatgat acccgcaacc ataatcgtga tggaaattac
    19441 ggcggacagt acggggcgtt ctataaatgt gctaactttc attgttctta attttgtttt
    19501 acttcaatcg gtgttccttc acgcaataaa cctacgcctt cggctacgat cacgtcgccg
    19561 ctattcaatc cggcgtttac gatatactct tgtcctccgt tcacacgggt cacttctacg
    19621 ggggcggatt gcgtcttgcc gtccactacc ttgaagacaa atacccggtc ttggatctcg
    19681 aacgtggcgg cttggggaat tacgacgcag ttatcgtatg taaccggaat gatcacattc
    19741 ccggagcccc cgctattcaa taattgctcc tcgttcggga atgcggcacg caagctgact
    19801 gttccggtgt tttgatcgat aatgccgctg atcgtctcga tctttcccgt ttggggataa
    19861 agcgatttat cgttcagttg aagctctatc tcgggcatat tctccaaggc tttgtctttc
    19921 gagccgtatt gacgggtcaa ggccaatagc tgattctcgg tcatggagaa atacacatac
    19981 atctcggaat tgtccgatac cgtggtgagc gatttgggca ggtttgcgct tactaatgcg
    20041 cctacacgat aaggcagggt tccgatgacg ccgttcgagg ggcttttcac ttccgtgtaa
    20101 gaaaggttgt tacgggcgtt tatctcttgt gcctccgctt gggctaattg ggcttttgcc
    20161 gagagtagag tgttgtaggc ggtctttagg tcgaactcgg aaactacttt gtttttatac
    20221 aattcttgtt tactgtcgta ggtcagttgc gctgtcgcta cagatgcctt agcggcctct
    20281 acgttcgcaa tggcggtgtt taaggccgct tgataaggga cttgatcaat aataaataag
    20341 acttgtcctt tttttacgct ctcgccttcc gttacgcaga gctttgtaat aaagccggat
    20401 acttgcggat aaatatcgat atcctgtttt cctcgtatac tcgccgagta attattggat
    20461 aaagttttct ccgaagtgaa tacggtcatt gtcgcatacc ctgaactttg ttggattaca
    20521 gggctttgtt tacacccaac agctacgata caccataagg cgatcgcagt cttcatcaat
    20581 cgattttgct ttttcatctt aactaatacc tatattttcg gatgcaaagc tactcgctta
    20641 tcggcgaacc attgtttcca caatgaggcg atgattgttc attttgagat ggaatgatcc
    20701 gttatatgct aatgatctct tatattcgcg ggcaaaatag tagacatatg aatccatttg
    20761 agatagagag aggagagtcg ttcataatag gcgattccga tttgagggag ttattggatc
    20821 gtccttacaa gagcggatat ggcatgatct tattttgcta taaaggaacg gcgaatatat
    20881 ccgtcgattt gagccgatgg gatatccggc gcaacacggt gatcgtattg ataccggata
    20941 cgatcctgac gttgaacgcg agtagcgagg atttcaaggt acaatatata tccttttcga
    21001 aggtcttgtt cgacgaggcc gtattccggc tggatccgcc ctttttccgc ttcataaagg
    21061 atagcccttg ctatacgcat cccgccgatc aggaggagac cataaatgtg atcatccggc
    21121 tgttttggct gatttacatg gatcggaata acgtgtaccg tgatatgatc gtgaaaaacc
    21181 agttgcaatg cttcttcctt aatatgtatg ataagacaag gtactccttc tcgagccgcc
    21241 agcaaaatgg gtgcaaccgt ggggaggagt tgttccataa gttcatcaat tgcatccatg
    21301 cccattatct cgaccagaaa gaggtctctt tctatgcgaa cgagctttgt atctctcccc
    21361 gttatctctc cactatcacc cggcaagtgg cgggcgagtc ggcgaagacc attatagacc
    21421 ggcatatcat attggagaca aaggtgttgt tgcgtaccac ggaaatgacc gtgcaggaga
    21481 taacgaacca cttgaacttt cccagccaat cctatctggg acggtatttc aagaagcata
    21541 cgggggagtc acccatagag tatcgaatga aaaggaagtg ataccactta ctgcaaggcg
    21601 ggttgcagta aaatagccat gaggttttgt ccttataaag ctgtggaagc ttttcccgtt
    21661 tgcccttgat cgaacgtatc cgtgattaag gtaagagcac catctcccgt cacgttgcaa
    21721 gccgtaccga agctatcttg caaagcgaat atcgtaagca ataatgccgt tcccgcctcg
    21781 tcgaaaccta ggatagcgat gatcaggccc aatgaggcga gcaccgtacc gcccggtacg
    21841 ccgggagcgc cgatcgcgaa gaaaccaagc aagatgataa atacgaacat cgtcgtgaag
    21901 tccggcatgc tgccatataa tatttgcgag acggtcaata cgaaaaacac ttccgtcaag
    21961 atagagccgc atagatggat gttcgcaaac agggggacag tcacgtcaat tacttcctct
    22021 cgcaagatct tgcttttctt ggcgcaggtc aaggccgtgc ccaaggtggc ggcggatgac
    22081 atggtgccta aggctgtcaa ataagcgggt ccgtagtatt tcaatacgcc ccagctattt
    22141 ttccgggagt agatcgatgc gactacatac agtaaggtca accagatgta atggcaaatg
    22201 atgacaatca agaggacgga taaaaagata ggcaactgct ttgtaatcgc cccctcataa
    22261 ctaaggacac agaaatttgc ggcgatgaaa agcggcagga ccggcatcaa gacccgttct
    22321 accaatttaa gtaccatgtt ctggaatact tccagcaacc tctccatctc ctcggattta
    22381 acccatgcgg tagaaagtcc cagcatcacg gccaatacca atgccgacat aacgctcatc
    22441 actggcggaa tctctagatt aaacaacatg ggagggatgt cttttagacc ttccgaggcg
    22501 gtttgaatat gcaaatgcgg tattaattca taacccacaa cggcgccaaa ggtagcggcg
    22561 ccaaccgatg acaggtatgc gatactaaaa gcgaataata agactttgga tgcgttgctt
    22621 ttcaagcggg cgatagaagg cgccacgaat cctagaatga tcaacggaac caagaagaaa
    22681 ataatctgtc ccgtaatttg ttttacgatc atgaccgctt ttaacacaga ctcgtttacg
    22741 gcaagcccaa ccagaagtcc gatcaagacg gccagtatca accgtacgat cgtgttggaa
    22801 agaatctttt tcagcatatt cggatgtttt tatttttcaa tgacagcaaa tataagatat
    22861 tttcttgtgt gaatgggtga gtggacaatt ttgattactt ttgtttgatg aaaacaagat
    22921 cgttggtttg tattttataa tcaagtaata tgaaaaacat gaaacaagct ttactggtag
    22981 cgggttgttt attggctacc actacgttat ttgcccagac tgagaaaggg gactgggctc
    23041 agtttggtcg ttatgcggag gctaacaaga ccgtgaaagt tccttcgaac gtggtattta
    23101 tggggaactc cattacagac ggatggtggc cggcggattc gactttcttt atccggaata
    23161 acttcgtaga ccgtgggatc agcggacaga caacctcgga gatgctagtt cgttttcgcc
    23221 aagacgttat taacttgaaa ccgaaagccg tggtgatctt ggcgggaatc aatgatatcg
    23281 ctcacaataa cggtgtgatc gccttggaaa acgtgtttgg gaacttggtc tctatggcag
    23341 aattggcgaa ggcaaatcat atcaaggtga ttttctgctc cgtattgccg gcttatgatt
    23401 ttccttggag accgggtatg caaccggccg ataaggttat ccagctcaat aaatggatca
    23461 aggagtatgc ggataagaat ggtttgacat acgtggatta tcattccgcc atgaaagatg
    23521 agcgaaacgg attgcccgct aacctgtcga aagatggtgt gcatcctacc ttggaaggct
    23581 ataagatcat ggagaagatc gtgctggagg ccattcataa aaccgtgaag taagcagatg
    23641 agaaactatt tattggcttt atcttgttgt acggctttat cttgttgtat gcaagtgaaa
    23701 gtttccgagg tatatacggc ggcggcagag aactctttac gtgctccggc cgttcctttg
    23761 gtcacgatcg acccctatac aagcgcatgg tcgtttgccg atcaattgaa tgatgagtcg
    23821 gtacggcatt ggaccggccg tgattatccg cttctaggcg gtatacgagt agatggtaag
    23881 tcataccgtt tcatgggaat ggacgatata caggtgacct cggtgatcgg tatggcctcg
    23941 gatggcttat gggaggccga ttatacgatg tctcagcctg ccggcgattg gttcgccgag
    24001 gcttatgatc cgaaaagttg gaagcgggga aaagccgctt tcggaacgga agataatccg
    24061 aatcgttcca cgctttggtc tacaggagat atctgggtac gtcgtacgtt tgactggcct
    24121 tcggatgagc aaaaggatgc cctctacctc caatattcgc atgatgataa tatcgaggtg
    24181 tatctaaatg gaaagcaaat cgccgtggca gggaacggtc tggactatga tttgctgaaa
    24241 gagataccgg aagcggtggc ggagagcttg aagcctacgg gtaacgtgtt ggccgctcat
    24301 tgccggaaca atgggggagg cgcttatgtg gatatgggaa tcatgcggaa ggtgaaacga
    24361 ggagatacgt tcgatgagaa agcgatccag aaatccatga acgtgatgcc tacgcaaaca
    24421 ttctatacct ttgagtgcgg tggcgtgagt ctggacttga ttttcacggc tcctttcttg
    24481 ctgaatgatc tggaggctat gacttctccg tttaattata taacctatca agtccgttcc
    24541 atcgacggta aagatcacga cgtgcaacta tacctggaag ccacgccgca atgggccgtg
    24601 aatacgatcg atcaagaggt gactttcgag aaaacggaaa cccctgattt aatttacctg
    24661 aagacaggaa caatcgatca agaggttctg gcgaaaaccg gggatgatgt acggattgac
    24721 tggggatatt tctatttggc tatccccaag aaaccgggag tctccgcaac gatcgacgag
    24781 tattatgcta cgaagaaagc tttcatgact actggtaatt taccggctgg atcgcaaagt
    24841 ctctcttcgg atatgcgtga gcaaatgaca gtcctcgctt atacggaccc gatcggcaag
    24901 gtctccaagg aaaccgtctc cggacatttg atgatcggtt acgatgattt atattcgatc
    24961 cagtatttcc aagacaaccg gatgccttat tggaagcacg acggaaaggt ggatattcat
    25021 caggcgttcg aaaaagggga ggcttcttac gaggatctga tgcggcgttg cggttccttc
    25081 gattcttctt tgatgagcga gacgagtgcc gtaggaggga agaaatacgc cgagctatgc
    25141 gctatcgcat atcggcaggc gatcgccgcc cataagttgg tgactgataa ggaagggact
    25201 ctcttattcc tttcgaaaga aaatttcagt aacggttcta tcggaacagt ggatattacg
    25261 tatccttccg cccccttatt cttagtatac aacacggatt tattgaaggg aatgatgaat
    25321 cccattttct attatagcga gagcggacaa tggaagaaac cttttccggc tcacgatgtg
    25381 ggtacctatc cggttgcgaa cggtcaaacc tatggtggcg atatgcccgt ggaagaaagt
    25441 ggtaatatgc ttgtgctagc gaccgctata gcaatagtgg atggcaatgc tgattatgcc
    25501 gcccaacatt gggaggtctt gactacatgg gcgaattact tgttgaagga aggccttgat
    25561 ccgaagaacc aactttgtac ggatgatttt gccggacatt tcgcccataa cacgaacttg
    25621 tccatcaagg caattatggg agttgccggc tacggaaaat tggcggagat gttaggtaag
    25681 gccgatatcg ctagacaata tacggaagtc gcccgtgaga tggccgctaa gtgggtgaag
    25741 atggcgaacg atggtgatca ttaccgcctg actttcgata agccgggcac ttggagccaa
    25801 aaatataatc tggtctggga tcgcttgctg ggcttgaata tcttcccaaa agaggttgcc
    25861 gctacggaaa tggcttatta caagacaaaa caaaataaat atggtttgcc gttggataac
    25921 cgggaggatt atacgaagtc cgactggatt ttatggtccg cttgtttgac cggatcgatg
    25981 gaggatttca atgcgctgat ggttccggtc tggaactacg ccaacgagac gacttcacgt
    26041 gttcctctaa gcgattggca ttttacttcc gatggtacgc aacgaggttt tcaagcccgt
    26101 tcggttgtcg ggggatattt tatgaagatg ctggaaaaga agctaggaaa ataatgtcat
    26161 tctaagaaac ggaaggaggt cattccttcc gtttcttagt tttgcgcata tggatattca
    26221 cagggagcga tgcctgtgat cttcttaaat ataaggctga aatactgtac gttcggataa
    26281 cctaattgtc gtgctaccaa agcgggagta ttaccgtttt tcagtagcat tgtcttagcc
    26341 acgctcaatc gtttgaactg aaaatattcc tccagtgttt tgccggtctc gaatcttaac
    26401 aggtcgttga agtaagcgac agaaaggtcc agttctgccg tacaatattc ggcggtgggt
    26461 agctggccgt tctctaattt accggaaatg atatactcgt cgaggagcct ttccaatttc
    26521 tccaagatag ccttgttctt attttcccgg gtaatgaact gtcgctcata atagcgtgta
    26581 caataatcca ataataattc aatgtggcgg gatagaatgg taccactgtg cgtatcgatg
    26641 gcatggtgaa gctcgtcctc gatgttttcc agacaacacg taactttggc tgtctcacgt
    26701 tgagagagat gcagagcctc ttctttgtga taagcgaaga aggtatagtt cttaataggg
    26761 ttgtccaatg acgtgtggaa caataggtcg ggatggaacg ctaaaaggta ccctttgttg
    26821 ggtagcgtat tattctcgct catgcggaaa atctcaccgg gtgtaagaaa cgccatcgta
    26881 gcgttggaat aatcgtaata cttacgtccg caacaatagc aaccgtccgg gcagtcttct
    26941 atcaagagga tcgcgtagaa ctcgaacttt acggcctctt gctctaagtt cgggctctct
    27001 agattgatga ggcttacttg tgggtgcagc gtcttgcatc ccaagcaccg gttacattca
    27061 tatacagtct taatatctaa catcttcttg aacgccttct atagattcgt tgatagaccg
    27121 atctgcgcac ggtattcact tggcgtgtac cctacccgtt tcttgaatag ccgacagaag
    27181 tgctgcggat attggaaacc gagggaatat gcgatttggc tgactgtgtc cgccgtgccg
    27241 gagatacgtt ctttggctag ctcgattact ttctcttgga tgtattcctg cggtgatttg
    27301 ccggtttcct tcttgaacat gtcaccgaaa tagttcgatg agaggcaaag cttgtcggca
    27361 aagtatttca ccgtaggcaa tccgtcctgt tcggcgagtg tactttcgaa atactcatcc
    27421 aacaggtttt cgaaacgtgt cagcacatcc cggtttgtct tgcctcgggt gatgaactgc
    27481 ctttcataaa aacgcataca ataattaagc agcagttcga tatggtttac aagtaaggtt
    27541 ttactatgtt tatccacgcc atgttccagt tccatacgga tgatcttcag gcaatccatc
    27601 acgatagatc tttcttcttc cgagagatgc aacgcctcgt ttacctcgta agaaaagaac
    27661 gtatatttct ttatattctt tccgagtgac gttccacgca gtaaatcggg atggaaaaga
    27721 ataccatgtg cgtttacttg gactttatcg gttgtcggat ttgtttccgc agtttgtccg
    27781 ggggcgaagc aaacgatcgt gccttcttgg taatcgtatg tctggcgtcc gtatttgata
    27841 tcgcaggctt tctctagttt tagatacagt gcgtagatgc cgtaattgaa gcggatgaga
    27901 tctacactac tcgtcgcttt attcaaatct atgacactga caagcggatt tagggtttcg
    27961 aggccgtata gtttgttata taggtctaca ctatctaagt taagtatctt atccataagc
    28021 cgtacgtatt taatcaataa ttctgtacgc aaaaatagag gataattcat atatagttat
    28081 aaccctaatt acggattata taaccattgt tacggattat gtgtatttac aggctttctg
    28141 gctgattcca caaaacctgt aattgaggtc atgacatccg taatttgtct acaaagggat
    28201 gctatttgag cctctatctt tgccttcgta aaaataaaca aggaacgaca tgaagaagtc
    28261 attaagagaa ttatgtacgg caatagccat atgcttttgc gctacgggaa atctgttcgc
    28321 tacagacaat caaattaata ccgatcatac aatggacaag aatttgaatc taattaagga
    28381 gtgggataaa gtattcccac agagtgacaa ggtgagccat agtaaagtta cttttcgtaa
    28441 tcgctatggc attacgcttg ccgccgatat gtacaaaccc aagcatgcgg atggaaaatt
    28501 gcctgctatc gctattagcg gtccgttcgg tgccgtgaag gaacaatcct cgggtttata
    28561 tgcgcaggaa ttggcagaac gtggatttct gacgatcgct ttcgatccgt catatacagg
    28621 cgagagtggc ggagagcctc gttatgtagc ttctcccgac atcaatacgg aagatttctg
    28681 tgcggccgtc gatttccttt cgacacgtga tgatgtggat gcggaacata tcggtatcct
    28741 cggtatctgc ggatggggag gcatggctct taatgcggcg gctatcgata ctcgtatcaa
    28801 agcgaccgta acctctacga tgtacgatat gagccgtgtg aacgctaatg gttacttcga
    28861 tgcgatggat gccgacgcac gttatgaatt gcgcaagcaa ctcaatgaac agcgtaccgc
    28921 tgacacaaag aacggctcat acgcccttgc gggaggtttg cccgatacgt tacccgacga
    28981 tgcgccccaa ttcttgaaag actactacgc ttattacaag acgaagcgtg gttaccacaa
    29041 gcgttcgctc aactcgaatg gcggatggaa caagacctcg gctttatcgt tcatcaatat
    29101 gcctatactc tcgtatagtg acgagattcg tagcgccgta ttgattattc atggagagaa
    29161 agcgcattca cgttacttca gcgaggatgc tttcaagaaa ctgaaaggtg acaataagga
    29221 attgctaatt atacccggag cgaatcatgt cgatttatac gatcagatga gtgtcattcc
    29281 cttcgataag attgaacggt tctttgtaga aaactttaaa taagattcat tatgcaacag
    29341 ataaaggata tggaatttag tggtgagcgt cctttgttcg cctctcacga tttacaatta
    29401 gacaatgtcg ttattcatgc cggggagtcg gcattgaaag agtgtagcaa tatcatagcc
    29461 ataggctgtc gttttgaggg taaatatccg ttctggcacg tggatggctt caccatcaag
    29521 aatagcctgt ttaccgaagg tggacgtgct gcgttatggt actcccaaaa tctagtgatg
    29581 acggatacac gggtggaagc cccaaagatg tttcgggaga tggacggtat cagactggaa
    29641 aacgtacaac tacccaatgc tcaagaaacc ctttggcatt gccggaacgt ggaattgata
    29701 aatgtgcaaa tagatcatgc tgattattta tttatgcacg gcgagaacat taaaatccgg
    29761 aactacgctc aaaatggaaa ctactcgttc cagtattgta agaacgtgga aatccgtaat
    29821 gcggtcatca actcgaaaga cgctttctgg aatacggaga atgttaccat atacgattcc
    29881 gagattaacg gcgagtactt gggatggcac tcgaagaacc tgcgtttggt aaattgcaaa
    29941 atctcgggta cacagccgct ttgttacgcc cacgatctta tgatggagaa ctgtacgatg
    30001 gcagatgatt gcgatctagc ctttgaatac agttccgtgc aggcgactat caatagcccg
    30061 atccgtagcg tgaagaatcc ccgtacggga agcatcaccg ccggaagcta tggtgaggta
    30121 atcctcgacg agaacattaa ggctccgggt aattgccaac tgaggctatg gaatgaacgt
    30181 acttgctttt ccgcataaag aatatgagat ataacttcga tgaaatagtg cctcgtaccg
    30241 gtacgaactc ctataaatgg gatagcgctg tggatacgga tgttctaccg atgtgggtgg
    30301 ccgatatgga tttccgtacg gcacccgtta ttatcgaaac cttacggcaa cgtgtagaac
    30361 atggtatttt cggttatact cgagtaccgg atgcatatta cgaagcggtg acaggctggt
    30421 ttgaacgtcg gcatggatgg caaatacgaa aagaatggat gatttgtacc tccggagttg
    30481 ttccggcaat ttctgccgtt atcaaggcgc taaccgagcc gggtgataaa gtactggtgc
    30541 agactccggt ttataactgt tttttctcgt ccatccgcaa taacggatgt gagattatcc
    30601 gcaccccttt gtcttatgcc catgatacat tcacgattga ttatgaggat ttggagaaaa
    30661 aagccgctga tccgaaggta aaggtcatgc tgttgtgtaa tcctcataat cccgctggaa
    30721 gggtatggac acgtgaggaa ctaagtcgta tcggcaagat ctgtatccgt aatggcctaa
    30781 tagtcgtatc agatgagata cattgcgaac tcgtatttcc gggatatact tttacaccgt
    30841 tcgcatctat ctcagaagaa ttcctacggc attccgtgac atgcctgtcg cctagcaagg
    30901 ctttcaatat cgctggatta caaatcgcca atatcgtgtg ttacgatgag aacctacgtc
    30961 ggaagataga ccgggcaatc aatatcaacg aggtatgcga tgtgaatcct tttggtgtaa
    31021 tagctaccat agcggcctat aatgagggag aggaatggct gtcgcaactg atcgattatt
    31081 tatggcagaa ttacttatac atgaaagatt tttgcgggaa atatctgccg gactttccga
    31141 taaccttgtt ggaaggtact tatcttgtat ggatggattg ccgtaagtta ggtaaatcat
    31201 cggaagaatt ggagcacttg ctgatcgaga aagcgaagct atggctcaat gccggaacga
    31261 tgtatggagc agaaggcgaa ggcttcatgc gttggaatat cgcttgtcca cgttcctcgc
    31321 tgataaaggg ggtggagctg ttcagggatt ttgtaggctg tgcctgttaa agaatagtga
    31381 tgatagaaaa cgtgagaagg ggaaaacatc tattgctttc cccttctttc atatatctct
    31441 cactagataa aagattcgtt ttactcgatc tcgatgctat gttttaccgg agtaagaatg
    31501 aacgtgaact catagtcgcc gtaaggaatc tggtattccg ggagtgcgat agttccccag
    31561 ctatttacac agcctaatcc catctgtacc ttatcgagac aaaggtttgt caagtcggct
    31621 tcctctactt ctggagagtg tctttgatcc tttcgggcac cgtcgtccaa agactctatc
    31681 gtataatgca aagcggaagc ggagaatggg gcagaggcta cgacctcgat accgttgcca
    31741 gcctcgttca gcattttcca ccagcggata tccgatttcg ttccattctc ttgcggacgg
    31801 atatacgaat agaattgctc gtctacggtc tggcggtaaa tagccaagtc cgcgttaccc
    31861 ttgcggtcga tataattctc cacgggacca cggccgtagt attcgatatt ctcgaaatat
    31921 ctcggcatcg gcatttgcat accgaagcgg aacatggggg ataccttggc attcttgtct
    31981 gctgtcattt tctgggtaac cttgatcgca cccttgttat tgatcacgta cgtcaagttc
    32041 aacttggcgg atacggtcgg catatcgtaa acggcctcta cgatcacttg cttgttctcc
    32101 atccgttggt taagagaagt cagcttcatt tccggattct tccatgcggc gtacttcttc
    32161 tgtaggccag ctccgaaatc attgtctgtc ggcgcacgcc agaagttagg agtcaaagcc
    32221 tctccttcct tgatcatgtc ttggccgttt acctcgtatt tgatcaggta accattctca
    32281 cggttgaatt cggtacggaa accacaacct tccacgatca ggtaattggc gtcgttatct
    32341 tgtacggctg gagccttggt ttcgatattg gttgtttcca cgtttttcaa atccatagat
    32401 ggagccttgt acgggttcaa cgtcagctga tccttggcca cggtatgtcc ggcgggtaat
    32461 aagccctcac ggttcttcag tttataagat acattcagca accattccgt gcattggcaa
    32521 gtctcgccta gatccaatcg gatcgttgat gtttgttggg gagctacttt caggtcatcg
    32581 acacgtccgc tacgaacaac cttgccgcct ttcagcattt cccattccag ataataagcg
    32641 gaaaggtcac ggaagaaatt ctcgttgtac accttgatct cacctttcga cagatcgccg
    32701 ggggttgtcc agatatcttg gtaataatac cccacctcgt acatatgcgg gttcggaaca
    32761 cgatccgggc tgatcaagcc gttatcgcag aagttattat cgctagcgtc gaacttattg
    32821 aaatcgccgc cataagcata gatcattttc ccgttcttgc cggtccagcg cacggattga
    32881 tccacgaagt cccagatgaa gcccccttga tatttcgggt atttacggat caaatcccaa
    32941 tattccttga aacctccttg agagttaccc atggcatgag cgtattcaca ttgtatcaaa
    33001 ggcttttgca tggagttatc ctcgctgtat ttagcgcaat cctcgtagtt gtaatacatc
    33061 gggcagaaga tatcggtctt tccgttcttt ccggcctgtt cgtattgtac ggcacggctg
    33121 gggtcttcgt tcttgatcca gtcgtaagcg gcctcgaagt taggaccgta tccagcctcg
    33181 ttacccaagg accagaagat gatactcgga tggttgaagc cacgttggac gttacgttgg
    33241 ttacgttcca gatgcgcttt cttataagat gggttcttgg ctaacgtctc ctcgccgtat
    33301 cccattccgt gagactctat attggcttcg gctacgacat agataccgta tttatcgcaa
    33361 agatcgtacc agaagttgtc atcgggatag tggcaggtac gaacggcgtt caaattgaat
    33421 ttcttcatga tctgtatgtc ctgtatcatg cgttcgcgtg aaacgacata accgccatcg
    33481 ggatccatct cgtgacggtc ggcacccttg aaaagaaccg gttgcccgtt cacgagtatc
    33541 tgggcgttct ttaattcgat cttacggaaa cctactttta cggggattac ctcgattgtt
    33601 ttgcctccct cttttaaagt agcccgtaaa gtatatagat agggagtctc cgcagtccat
    33661 ttgtggggag aggagacttc tatcgtcgtg ctgacctttc cggaagcgtt caaggattgg
    33721 gtagtgacag ctttattctg ggcatccaat agttcaagct ctactgtacc tttacccttc
    33781 atggtcaggt tgactgccaa cgagccattt tggtattgag cgtccagatc cggagtcaca
    33841 cgtatatcgg cgatctgttg ctttgggtta cgggcgtata aataacaatc acgtccgaca
    33901 ccgctgtaac ggaagaaatc ttggtcttcc agataagtgc catcacacca gcggaatact
    33961 tggaaagcaa tcaggttttt ttgtccgggt ttcaagtaag gagttaagtt aaactccgct
    34021 tccagcttgc tgtcttcgct atagcctacg tacttcccgt ttacccacaa atacatattg
    34081 gaggtaacgg aaccgaaatg ggcgatgatc tcttttccgt tccagctggc aggaaccatg
    34141 atctcacgac ggtaggaacc cacatggtta ttaacggtag ggacctcggg cgggttgttc
    34201 ttgaattgct cacgccaagc gtaaccaacg tttacgtaga gaggatctcc atatccgttc
    34261 agttcccata caccgggcac aggcatattg ttccatcctt tgtcgttgta atcggtccgc
    34321 cagaaatcgg taggacgagc gtcagcgttc tttacccaaa agaatttcca aggaccgttc
    34381 aaggtcatga agttctggga ttgttccttg gcgtccttcg ctgccacctc ggcggtctcg
    34441 taggcgaaga aattggcgtg catcggggca cggtttacgg cgttgacctc ggggtctcgc
    34501 cactcattcg actgggctac cgctgtgaaa gccaaagcgg caaacagtcc ggtcataagt
    34561 tgtcttttca tgctattata tttttaatct gctttacgga attgcaaaac taagaataaa
    34621 attccgggta tggcaataat tccggcggaa actaacaggg cgacacgtaa agaatagaaa
    34681 tcatttagcc aacctataaa tggggcgatg gcagcgaata tcaagcggat cacaaagtta
    34741 cggatcgaca agaccgtagc ccgcatctcc gagaaggtca tttgattaat gtaacctttc
    34801 aaaatcggtg tggcgaagcc ccggactata tagaaaatga acaagatcgc taatccccaa
    34861 taagtaaggt tataagcgag cgatatatat ccacctacga ttataagtag tataaacgtg
    34921 tttgatttac gcatcccgaa ataccgctct acctgatcag aatagagggc ggacaatccc
    34981 acagtcagat tgagcacggt ccaaatgaca ccgtaatagg aggtcggggt ttccaacttc
    35041 atcaatacgg gctgcacgaa ccatgccatc gttaatgtag cggctccgat gataccggag
    35101 aacatgatgt tatagcatag cttacggttc gtgaccaagg aatatttcaa gatgcggaga
    35161 atctcggaaa ccgggttctg caccttgctc ttagtattga attcctgcaa ggcgaacgcc
    35221 gctggaatgc cgataaaggc gacaaacgct tgggcgtaaa acggcaatcg caaggaatag
    35281 gcggccagca atccaccgaa tatcccggcg atggcctcgg cgaaattacc gatcatcgtg
    35341 atacgtccct cataccgcaa ataaagttct tcttttttat atcgtacggt tgtatcgtag
    35401 agcagcgccg aatccgctcc gtttaccaag gtttgcccgg ttcccaacaa aatctcggcg
    35461 aagagaaatg ccgtgaaagt ggaggtgaaa gaataacata ggtaccctcc aaagaaaagt
    35521 atacaaccta gaatcaagca tttcttacgc ccccatacgt ccgccagata gcccgaggga
    35581 atctccaaag tgacagcggc gaccgagtag acactcttca aaataaacac gtcttgtagt
    35641 cctaaaccat gatcctcgta gaataggaca atgataggca ttacgagcga gaaccatttg
    35701 gataacttga tcagatagag agcgagtata ttttgtttca tatttttcaa cgggattgcc
    35761 ctgtcgtttt tatttagaca cgcgaatgta tgaattcttt gccaatagcc tgaacttttt
    35821 taggaagctt ctgttctttt tgaaaaagga aaaatatggt attcaatcaa cttgatattc
    35881 atttactgat tacggccatt tgtgtcatat catccgcctt gatatgctat acgatcgggg
    35941 tctggggcga gcgttttcaa ggacagttaa aagcgtggca tctttggttt tttgtattag
    36001 gactttatgc ggacgctatt ggaacgggct tgatggagca tatcgcccaa ctgacccatt
    36061 tacatgatac ggtacatacc gtaacgggaa ttatcgctat ttgcttgatg ctgatccatg
    36121 cgatctgggc gatttggact tactttaaag gttcgttaaa agccaaacag catttcaaca
    36181 gatttagcat tgttgtgtgg ttcatctggt taattcctta ttgcatcggt atctacatgg
    36241 ggatgtctct ccataaatag aggccatcgc tcatatatct tgagaaataa atcgtacatt
    36301 tggtgatatg tttactatat aaacgaggtg atcgccctct acgagcgttc cgccgagatg
    36361 aatccattct cctcgaagtt cgatgcttgg caagccggca aatgtcaatt aacagaagag
    36421 gagaaactag gctatgagct tttcaaggaa aaagggctat gtgccgagtg ccatatcttg
    36481 gatcccgacg aacgggccgg gaaggtgcta ttcaccgatc atacctatga taatctgggg
    36541 attccctcaa atccgggcaa tccattcttt aaggtttcgg ctccctataa tacgtgtggt
    36601 aaggatacga tggatcttgg cttgggctca cgactgcgtg atccggaaga atacgggaag
    36661 ttccgtgtgc ctacgctccg caatatcgct ctgacagctc catatggcca taatggatat
    36721 ttcaagacct tggaggagat cgtacatttt tataacgtaa gggatgtaga ggatttcccc
    36781 ccggcggaat atcccgagac cgtaaataag gatgaactgg ggaacttagg tttatctcag
    36841 gaagaggaga ctgcgattgt cgctttttta cgaacattga cggattgcat caaataaaaa
    36901 tcagtctttc caaaaacttt ctccagccct tgatagtttt cttataaaat aaaaagaaga
    36961 gtttaaacta tggcgaagaa agttgcggac cagttagtgg atacgctgga aaaagcaggc
    37021 gtacgacgta tatacgccgt gacaggcgat agcctgaatg aggtgaacga ggctgttcgg
    37081 aaaaacggca gattgcggtg gattcatgtc cgtcatgagg aaacgggggc ttatgccgct
    37141 gcggcggagg cccagttgac aggcgagttg gcttgttgcg caggtagtag tggccccggg
    37201 catgtacatt taattaatgg gctgtatgat gcccaacgat ccggagcacg ggtcttggcg
    37261 atcgcttcca cgatcccttc ccgggagttt ggtacggaat atttccaaga gacaaatacg
    37321 atcaaattat tcgatgattg tagctattat aaccaagtag ccactacgcc ggaacaattt
    37381 ccccggatgc ttcaaggcgc tatgcaagcg gcgatttcat catgtggggt cggggtgatc
    37441 ggacttcccg gtgacttggc ggcagagaat gctacagcgg gtttgtcctc taccttttct
    37501 tttcctacgc gacaacgggt ttgtcccgcc gaacaggaaa tccgggaatt agcggatttg
    37561 ttgaataatg cgaagaaagt gacactttat tgtggaatag gggcgaaaga tgcccttccg
    37621 gaattggtgc agttggctaa attactgaat gctccggtag cctattcttt caagggtaag
    37681 atggagatcc aatacgataa tccgaacgag gtggggatga ccggtctatt gggcatgcct
    37741 tccggctatt atagtatgca tgaggcagag gtgttggtgt tgttgggaac cgattttcca
    37801 tacgaggcat tcatgccaga gagcaacacg atcgtacagg tggatatcaa tccgaatcgt
    37861 ctggggcgtc gtgccaagat acaattgggg ctttgtggcg atgtgaagga tactttggat
    37921 gagttgattc cgttgattca ccagaaagaa gatgatagtt tcttgcggga acagttggct
    37981 aaatatgaga aagttcggga aaatctccgt tctgccgccg ctgtccgggg gaaagaagag
    38041 aagatacagc cagagtacgt gatctcggtc gtagacgagc ttagctcgga cgacgccata
    38101 tttaccgtgg atacgggtat gacttgtgta tggggtgccc gctatttgca agctacgggt
    38161 atgcggaaga tgttgggatc attcaatcat ggctcgatgg cgaacgccat gccgcaagcg
    38221 ataggggcgg cattggctta tcccggcagg caagtcgttg cgttgtgtgg tgatggaggt
    38281 atctcaatgt tgttgggcga ccttgctacg atcgtgcaat accatttgcc gattaaatta
    38341 atcgtattta ataaccgttc cctaggaatg gtaaaacttg agatggaggt ggccggactg
    38401 ccggattggc agaccacgat gctgaacccg gatttcgccc gggtcgccct ttcaatggga
    38461 atggcgggct acaacgtgat caaccccgac gatgtattcc ccactttgca gaaagtgttt
    38521 aacgctgacg gaccggcctt ggttaacatc atgaccgatc cgaacgcatt agcgatgcct
    38581 cccaagattg agttctccca aatgcttggt tttgcccaga ccatgtataa gttaatgatg
    38641 gaggggcgaa gcaaggaggt cttggatacc atcgatacga atctaaaaca ttggaaagat
    38701 gtgttttaaa ctctcaaaag agctggataa ccgctttaga tttcgcgctt tgaatggcag
    38761 cgtccaatat ccgcactacc attaggttat tctccaacga ggaaaggtcc gtgggaggta
    38821 cgtcaatctc tttacggaca gcggctttca agaaataaaa ggaatcatta taaggagcgt
    38881 tcaaggaagg tgctatttct tggcgctcct ttccgttggt ataaattcgc atttccttag
    38941 gcgtatcttg gtaaatatat cctttgtcgc catagatatg catatctttt ctacccatcg
    39001 gccaacacca tgatcccatg atctggacgg ttgcggaagg atattccacg ataatagttg
    39061 cgtcatcgtc taccttggga taaagattcg gtttattctg ccgtagtacg gcgtatacgc
    39121 taagaggctt ttcatctttc atgagacggg tggctaagtt ggctccgtaa catccaaaat
    39181 cgataactgc cccgccgcca ttcagcatgg ggtcggttaa ccagtccgtg aactcttttc
    39241 cgcagttgat ctcgaaggga ccttgatgcc cgtcgtatac gttgatacga tcgatcttcc
    39301 cgatagcacc gctgtcgata aggcggaatg cctcatggtt ggtattatac cacgtagtct
    39361 cgtagttggt aagcaacaag atatttttct cacgggcgag cgatgccatt cgggtagcat
    39421 gttcgttatt gacggctaat ggcttttcta ccataacatg tatgcctctc ggtgcgcaag
    39481 cctctaccac acgaagatgg tcgtggatcg gctcgtatac gatgaccgcc tccggatggg
    39541 tcttatccag catctcgcca aggtccgcat agaataggtt aggatccagc ttatcccgca
    39601 gaccgttatg ttcccgtaag taatcatctt tctcagcgac tcctacaatc ttgaaatcgc
    39661 ctctatccaa acggcttatc acctcccata gatgtccgtg ggatactcct gccacggcca
    39721 gtcgcaaagg ctctccatct tgccctttcg ccgtgagagt taagaacgta aatgcacata
    39781 acataagtaa gtaacgtgtg atcttgtgta tattcatgat attatctata tatagttttt
    39841 acaaagatat acgattattt cttacctttg caacccatta cttattcaga ttaaggaaaa
    39901 cagtataatt tagaaatata aagaaatggc aaaagagctg aaagaactta caccgagaag
    39961 tgtaaactat tcgcagtggt accaagattt ggtaattaag gcagatttgg cggagaattc
    40021 cgccgtgcgt ggttgtatgg tgatcaagcc ttacggatac gctatctggg agaagatgca
    40081 acgtatccta gacgatatgt tcaaggaaac cggtcatgtg aacgcttatt tccccttgct
    40141 gatcccgaag tctttcttaa gcaaagaagc tgagcacgta gaagggttcg ccaaggagtg
    40201 cgccgtggtt actcactatc gtttgaagac aaatcatgac ggtacggggg ttgtcgtaga
    40261 tccggcagct aaactggaag aggaattgat cattcgcccg acttcggaga ccattatatg
    40321 gaatacatac cgtaactgga ttcagtctta ccgcgacctg cctatcttgt gcaaccaatg
    40381 ggcgaacgtg atgcgctggg agatgcgtac tcgcttgttc cttcgtacgg ctgagttctt
    40441 gtggcaggaa ggccataccg ctcacgctac tcgtgaagaa gcggagatag aagctaagaa
    40501 gatgcaagag gtttacgcga acttcgctga gaattatatg gcaatgccag taataaaggg
    40561 cgtgaagtct gagagcgagc gtttcgctgg tgctttggat acctatacga tcgaggcgat
    40621 gatgcaggat ggaaaagctt tgcaggcggg aacttcccat tttttgggac agaacttcgg
    40681 taaggctttc gacgttactt tcatcgacaa gaacggcaag agcgactatg cttgggctac
    40741 ttcttgggga gtttccacac gtttgatcgg tgcgttgatt atgtctcatt ccgatgataa
    40801 cggtttggta ttgcctcctc atttggctcc gattcaggtt gtgatcgtcc cgatttatcg
    40861 tagcgctgag caattagcgc agatcagcga gaaggtcgct ggtatcgtgg ctaagttgaa
    40921 ggcgttgggt atctccgtga aatatgacga cgctgataat aagaagccgg gctggaagtt
    40981 cgctgagtac gagttgaaag gtgttcccgt gcgtttggct atgggtggtc gtgatttgga
    41041 aaataataca atcgaggtga tgcgccgtga tactttggag aaggaaacga tcacttgtga
    41101 tggcattgag gaatacgtga agaatctgtt ggaggaaatc caagcgaata tcttcaagaa
    41161 agcgtacgat caccgtgagg ctaacatcat aaacgtagat acgtatgagg aatttaagga
    41221 gaagatcgag gatggcgtct tcatcatggc tcactgggat ggaaccccag agacagagga
    41281 attgatcaag aacgagacaa aagctacgat ccgctgtatt cctttagctg gagataagac
    41341 tccgggtaag tgtatggtga caggtaaacc gtcggcttgt cgggtactgt tcgccagagc
    41401 ttattgattg ttatgctaaa agatgaaata aaatgaggga tgctttaacc gaagggcatc
    41461 cctctctaag aaaatgagct accacgaatt tatacttgtc gttaacttta gtagcatcat
    41521 tatcttggtg ttattggcga tgttgttatt gattgccact cggtttcgtg gcgagagtgg
    41581 ttatgccgca gcgattatcg ttcttcctaa catccctgtt tatatttaca acatgagccg
    41641 catgcttggt tggcatgata taacgttgtt ctttttccct atcagttatt cggtcaatac
    41701 gctgttgatg ccgttgctgt ggttatttac ccgccgcaac tttgatcttg atcctcgttt
    41761 caagcctgtc caattgttgc attttttacc ggcgattgtc tgtgtcgtta tcgtgttatc
    41821 cattcctatg cggaagcgta tggagagtat acttcatgag gtcaccggtg atgatacttg
    41881 gatcggtgat tttaacgctg ccgtgattac ctcgcagatg atcggttatt ttgtcgctat
    41941 ctttatttat ctttaccgga agaagcagta tataaaggat aattggtctg atgccgaata
    42001 catgcaaaag gaatggattc cgaaacttat gatcctgttc gctgccttgt ttgtcaccgt
    42061 gatgacctgc tatgcgattt ggcctcggac tgatgcttgg ttgatacaga tattgaatgt
    42121 gatggcgatg agcttcctcg tctataattt tattgctcat ccaactgttc cttatatcca
    42181 aggaacgtca cggatgctcg ttaaggatga gacggtaggg tttcagtcta taccagacga
    42241 ggaacaaatg agagatatat gttcccaagt gaaagagtat ctggagacaa caaatgcttt
    42301 cctgcgaaag gacctttcct tatccatctt atcgagagag actggtattt accaaaaatt
    42361 actttctcgg tcgatcaacg aatacttaaa acagaacttc ttcgagctta tcaacgagat
    42421 gcgagtgggg gaagccaagc gaaggttgct cctgccggag aatgctggtc atacggtaga
    42481 tagcctttat gaggaatgtg gttttcggac tcgttccacg ttcttcttgg catttaagaa
    42541 ggtagagggt ttgtctcccg cccagtggct taattcggta aaaaaacata cggatcaata
    42601 aacgcaacag ctaaaaagag tacataaact ctttccgggt ctgattttat tactatattt
    42661 gtgtcgctat cgtcagatag cggacatatt tagacactag gaaagtgttt agcttcgttc
    42721 tcagagataa aatctggtaa atttttcacg ggagaataag ttgtactctt cacgtcattg
    42781 ttatatgcta tacgtatatg gacaaagggc gtgggctgtt gcttatttac cgtacgggtt
    42841 taccagagcc tatctcttaa ataagttaat agtcccacgc tttcctcata ttaatactat
    42901 ccggatcggg gcttaccgga tgtacatctt cgaggcatta tgaaaaaata tctaccacgt
    42961 ttctctttct ttttaatgat tttactccat ttcatcatga aatcagtctg aatatacagc
    43021 tttcggactt ctctaaacat cttgttttag gtgattcggg aaataaacac tctctttgcg
    43081 gtatcgattg aatctgtttg tttacttctg aaagtatttt tgtatataaa gcatttttgt
    43141 tttatatgca ttttattgat gtggatactc tcgctgatac cttcttgtca tcgagaggga
    43201 gaggttggtc tttcccaaaa tgatcaggtg ggtatagata gtgtggtctc ggcctgtccg
    43261 gacatcgatt ctctacaatc atgtctaagg tatttcgaga gaactgcaaa tgagctggga
    43321 gtgatactcg cctataagga attagaggta cgttaccggg aagcggcccg ttttaatgag
    43381 gcgataggat gccaccggga aggcttgcga ttggctatgc aaaggaaaga tacctcggag
    43441 gtcatacagg ccttgaataa tatcggtacg aacttccggc ggttaggtat catggacgag
    43501 gcctccaatt atcattatag ggcattgtcg ttgtgcgaga gactgggtga taaggaaagc
    43561 tataaagcaa gaaaaaaccg gaccatttcc ttgagtggta tcggaaacgt gtatctaaca
    43621 ttggaaaatt gcgagatggc cgacagtatt ttccgaatag cgctggaaga ggaacgtacc
    43681 ttggatagtg atctcggctt ggccatgaac tatgcgaacc ttggctctat cttcgagatg
    43741 cgtggcatga tggattccgc ttttgtttat tacaattatt ctatggagca taatcgtgcg
    43801 gccgggtctg ttgtcggcat ttcgctttgc cataaccata taggacgctt gttcgagaaa
    43861 aagggacaat gggatcaggc gatacgcgaa tatcgtaacg catacgacct tatggtggcg
    43921 gacaacgatc tgtatcattg gctggaatcg tgcctggcct tggcacgggt gaatatctac
    43981 aagggagatc tgcgaatggc ggaggctttc ttggagcatg cggagggtgc cgctaaggtg
    44041 ccgcgggcgt ggaagcattt gtcgagcgtg tatcatctgg attacttgcg ttataagaag
    44101 ctgggtgatt ataagaatgc cctcaacgct tatacatcaa gtctcgctta tgctgatagc
    44161 atgcgaaata ctgagaatat gaaccatata cagaacctcc gtgtggacta cgagaaagag
    44221 aggagcaacc ggaagctttc attgatacag aagaattatg agatggggca gcgtaccaag
    44281 aatattttcc tgatcgcttg cttgatcgta ctcttcctta cggtggtagc gatgggcttt
    44341 ttatggtatg ccttgcggat gaagtcccgc aatcagcagg tgatgcggcg catggaggag
    44401 gtgagggcca atttcttcac gaatgtcacg catgagtttc gtacgccgct gacggttatc
    44461 ttgggtgtgt cggaagagtt gcggaaaggg ggaataggcg aggaggaact caagaccggg
    44521 ctgaatatga ttggacggca gggaaagaac ctgctggaat tggtgaacca attattggaa
    44581 gtggcgaaag tgagatctga gattggcgat ccggaatgga ggactggaga tatcgtagct
    44641 tatacgagca tgatcgtgga agataaccgg gcgtatgccc gccaagggca ggtagacctt
    44701 tgttttactc cttcggagac gattatcagc atggatttcg tgcccgagta tttccggagg
    44761 atcatggata acttactccg taacgctatc aagttcacgc cgagaggtgg gagggttgtc
    44821 gtgacgatgg agtgtgtggg gagtatgctt gtcacgcatg tggcggatac gggctgcggt
    44881 atagccgagg aggacttgcc gcatatcttc aaggcttttt acctaggtga gaccggaggg
    44941 gcaggcacga tgggcacggg gatcggcctt tctttggtac ggcagatggt gaggagcatg
    45001 g
//
LOCUS       DBMDTB010000023        43830 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_351_length_43830_cov_10.829838, whole genome shotgun sequence.
ACCESSION   DBMDTB010000023 DBMDTB010000000
VERSION     DBMDTB010000023.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 43830)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 43830)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43830
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_351_length_43830_cov_10.829838"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            234..530
                     /locus_tag="ACZPB4_05730"
     CDS             234..530
                     /locus_tag="ACZPB4_05730"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HIR1097755.1"
                     /translation="MNKQSVISLLRKAKQPLSQSCGVKQLGLFGSTVRESNTESSDVD
                     ILIDFEDDKETYSNFLLACEILEKLFDRLKVDIVTLKGLSPFIGQQILKEVEYV"
     gene            599..934
                     /locus_tag="ACZPB4_05735"
     CDS             599..934
                     /locus_tag="ACZPB4_05735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinoglycan biosynthesis protein exoh"
                     /protein_id="HIR1097756.1"
                     /translation="MGEPWCRYLHNVGIIVGCVCFISLTATCLERGLCRVSGFLAGSS
                     FFVYAYHGMPLALAIKVVVRYLPPGSELEVIGLYLGSACVVIGIGLALYGGMRRCVPS
                     FLLLITGGR"
     gene            1657..3180
                     /gene="purH"
                     /locus_tag="ACZPB4_05740"
     CDS             1657..3180
                     /gene="purH"
                     /locus_tag="ACZPB4_05740"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004310431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HIR1097757.1"
                     /translation="MAATKRMKRALVSVFHKDGLDEILKKLHSEGVSFVSTGGTQSFI
                     ESLGLPCDAVEDLTSYPSILGGRVKTLHPKVFGGILARRENENDQKQLAEYEIPEIDL
                     VIVDLYPFEETVASGAEEQAIIEKIDIGGISLIRAAAKNFKDVVIVASKAQYQPLMDL
                     LNEKGAETSIEDRRWFAKEAFAVSSGYDSAIFNYFDGREGSHFRATVDSPMHLRYGEN
                     PHQAAKFYGKFNDMFDQIHGKEISYNNLLDIDAAVNLIDEFDELTFAILKHNNACGIA
                     SRGNVVEAWKEALAGDPVSAFGGILITNTTINKEVAEEIHKIFFEVIIAPAYDADALE
                     VLQQKKNRIILIRKDCKTCPMQFRSLLNGVLMQEKDLSIQGKADLEPMTDKQPTASEV
                     EDLLFANKIVKNSKSNAITLVKNKQLCASGIGQTSRVDSLRQAIEKAKSFGFDLNGAV
                     MASDAFFPFPDCVEIADQAGITAVIQPGGSINDKLSVEYCNQHGLAMVKTGVRHFKH"
     gene            3192..4211
                     /locus_tag="ACZPB4_05745"
     CDS             3192..4211
                     /locus_tag="ACZPB4_05745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000902 - cell morphogenesis [Evidence
                     IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HIR1097758.1"
                     /translation="MGLFSFTQEVAIDLGTANTIITCNDKMVVDEPSVIALDARSDKV
                     LAVGKVAREMYEKTHPNIRTVRPLREGVIADFYAAEQMIRGFIKMASGRKRWFAPSLR
                     MVIGIPSGSTEVEIRAVRDSAEHAGGRDVYMVFEPMAAAIGVGIDVLAPEGNMIVDIG
                     GGTTEIAVISLGGIVSNKSIRMAGDDLTADIVEYMRRQHNVKVSERMAERIKINVGSA
                     LTVLEDAPEDYVVHGPNQMTALPMEVPVSYQEIAHCLDKSISKIEAAILSALEQTPPE
                     LYADIVKNGIYLAGGGAMLRGLDKRLRDKMNIQFHIAEDPLHAVAKGTGVALKNIEKF
                     NFLIR"
     gene            4314..5168
                     /gene="mreC"
                     /locus_tag="ACZPB4_05750"
     CDS             4314..5168
                     /gene="mreC"
                     /locus_tag="ACZPB4_05750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HIR1097759.1"
                     /translation="MRKLLEFLIGKRHWFLFILLEAVSLMLVYRNNAYQRNIIFSSAN
                     VVTGYIASISGSVTSYLNLRDINKELLERNGQLELQMLDLQDQLDALIADTVSFKGFA
                     PDSTEQFPYSFVVADVVNNSVTHLSNYITVDKGKLDGIMPDMGVVSERGVVGIVSTVS
                     DHFSVIIPLLNPKFRLSCKVLGSSYFGSLSWNGRNTLYANLDELPRHVEFQKGDTIVT
                     SGYSAVFPSGIIVGTVADFEKQHDDNFYSLQVELATDFQALNNVRIIKNFRQTEQIGV
                     EQEAKRND"
     gene            5161..5679
                     /gene="mreD"
                     /locus_tag="ACZPB4_05755"
     CDS             5161..5679
                     /gene="mreD"
                     /locus_tag="ACZPB4_05755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HIR1097760.1"
                     /translation="MINNLLRGFIYFVVFVLIQVLILNNIHFLRIATPFLYLYFIIKM
                     PVGSSRTQVVFFSFIAGVVIDTFSNTPGMHAAACTLAGFCREPLIRVFMGKDLPEGIY
                     PSCKTFGFGGFFRYVLSFVLIQHTTLFVIESLTLFDPLFLVVRILSSVVMTTLLICTV
                     EAFNIESQKSGE"
     gene            5669..7537
                     /gene="mrdA"
                     /locus_tag="ACZPB4_05760"
     CDS             5669..7537
                     /gene="mrdA"
                     /locus_tag="ACZPB4_05760"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HIR1097761.1"
                     /translation="MENNTKYEFENRRYVLGGAVILLVIIFIIRLFILQVVDNDYKAW
                     ADSNAFLKKTLYPSRGMMYDRNGKLLVYNQPAYDVMLIMREIQPFDTLDFCDVLGITK
                     EQFLKRIADIKNRRLNPGYSSYVPQVFMNQLSAQEYGVLQEKLYKFPGFYIQNRTIRQ
                     YEYPNAALVLGNIGEVNRKDIENDSYYTQGDYSGRTGIEQSYEEYLRGVKGVEILLRD
                     AHGRIKGRYEEGLHDIQPESGKNLKLSLDMDLQAYGEKLMQNKLGGIVMIEPETGEVL
                     CMVSAPTYDPSILIGRQRGKNYVALQKDPLKPLFNRPLMAQYPPGSTFKPTQGLIFLQ
                     EGVITPETQYTCAHGYTFRGGKPACHGHPSPLNLVGALATSCNSFFPWGLHDMIDSRK
                     RYPSVQEAFEVWKNHMVSMGYGYKLGIDLPGEKRGFIPNSKFYDKVYRGRWNSSTVIS
                     IAIGQGEILATPLQICNLAATVANRGYYITPHVVKEIQDTPLDTLYSKRHYTSVDTHY
                     YSYIAEGMRGAVTGTAYGGTCRGAALPDIEVCGKTGTSENPHGKDHSIFMGFAPYQKP
                     KVAIAVFVENAGFGATYAVPIGKLMLEKYLKGEISEANKATEEYIMNAVILPNNAL"
     gene            7527..8972
                     /gene="rodA"
                     /locus_tag="ACZPB4_05765"
     CDS             7527..8972
                     /gene="rodA"
                     /locus_tag="ACZPB4_05765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein RodA"
                     /protein_id="HIR1097762.1"
                     /translation="MRYRKTEIWKSVDWITILLYLIMVIAGWFSICGASYEFDNVGLF
                     DPSGRPGMQMIWIGTSLALIFVILMLESDFFDIFAYLIYACVIVLLIATIFLAPNIKG
                     SHSWLVLGPIRLQPAELAKFATTLAVAKFMNGYGFKLTTVKNFSITLFLIFLPMVCIL
                     LQKETGSALVYLAFFLMLYREGMTGYILLIGVCAVVFFVTGMKYSEVMVGITPLGELI
                     VSCLVLLITMGLVGSVRKDYISVKIMLGGIASTFLIGYVVSLFVPVNFAWISIGLVGA
                     ASIYLFYLSIRNWVWHYALIALFALGSICFLFSVDYVFNDILEPHQQIRIKVSLGLED
                     DPSGAGYNVNQSKIAIGSGGLSGKGFLNGTQTKLKYVPEQDTDFIFCTVGEEQGFLGA
                     SAVLIVFGLFILRLIVLAERQDNAFGRVYGYSVASIFFFHLAINVGMVTGLTPVIGIP
                     LPFFSYGGSSLWGFTILLFIFLRLDASRKER"
     gene            complement(8932..9504)
                     /locus_tag="ACZPB4_05770"
     CDS             complement(8932..9504)
                     /locus_tag="ACZPB4_05770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gliding motility lipoprotein GldH"
                     /protein_id="HIR1097763.1"
                     /translation="MTNLSNRSNRPDLIKRRIGQRQSLRLKKFIAACVTCFLCFSCEN
                     EAVYDQYQAIQNTSWEKNKEYYFTFLIEDISVPYDLTLEVRNNNMYPYQNLWVFCSEE
                     LPIGPLKRDTIECMLADEFGKWYGDGISLFQSSFPIRSAYYFPVKGQYTFSFRQGMRN
                     DQLPGIQEIGLRVLPSSTNAPSEKRPNEEK"
     gene            complement(9425..10939)
                     /locus_tag="ACZPB4_05775"
     CDS             complement(9425..10939)
                     /locus_tag="ACZPB4_05775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PSP1 domain-containing protein"
                     /protein_id="HIR1097764.1"
                     /translation="MDFILDKGSSHMGCKGCSKRQNNKLNTYDWLCDVPDAEGSTDFV
                     EVQFKNTRKGYYLNSAKIPLEKGDIVAVEASPGHDIGTVSLTGKLVLLQMKKNNVRTE
                     AEPKRIYRKAKPTDIEKYEEAKAKEHATMIRSRQIAADLGLNMKIGDVEYQGDGNKAI
                     FYYIADERVDFRQLIKVLAEAFRVRIEMKQIGARQEAGRIGGIGPCGRELCCSSWMTS
                     FVSVATGAARYQDISMNPQKLAGQCAKLKCCINYEVDTYVEAQKRLPSREIVLETKDN
                     NYYHFKTDIFKREITYSTDKSFAANLITIPASRAFDVINMNKKGMKPISLEADTKPQP
                     PKRDAQDILGQESVTRFDSVKKKKKKRPANKNNGENNGNGNGANTTATAVTNTDAPVS
                     ENKNNGGNGAGGNNRRNGGNNRNSNRENNRDRENNRENNKDNSRENSRENRENNRDNN
                     RESNRNNRPKQRPRANNDKQSNNDKPANNDKPQQPIKQARPDKTENRPETKPEA"
     gene            complement(11114..12301)
                     /gene="spt"
                     /locus_tag="ACZPB4_05780"
     CDS             complement(11114..12301)
                     /gene="spt"
                     /locus_tag="ACZPB4_05780"
                     /EC_number="2.3.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010802415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004758 - serine C-palmitoyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0046513 - ceramide biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine palmitoyltransferase"
                     /protein_id="HIR1097765.1"
                     /translation="MKLLQEKLAKYDAPQRAMAMGIYPYFREIQSDQDTEVLISGKKV
                     LMFGSNAYLGLTNHPKVKEAAIEAIKKYGTGCAGSRFLNGTLDLHLQLEKRLAEFVGK
                     EDAIVYSTGFQVNLGVVSCITGREDYILWDELDHASIIEGHRLSFSTKLKFKHNDMDS
                     LEKQLQKCEPDKVKLIVIDGVFSMEGDVAKLPEIVALAKKYNASVMVDEAHGIGVFGD
                     HGRGTCNHFGVTNDVDLIMGTFSKSFASIGGFIASDEPVINYLRHHSRSYIFSASNTP
                     AATAAANAALDIMLSEPERIQHLWDLTHYALDGFRNMGCEIGHTSTPIIPLFIRDNDL
                     TFLIVKELFEAGIFVNPVVAPAVASEDTLIRFSLMATHTKEQLDYALETIHKVFKSHG
                     LVD"
     gene            12500..13471
                     /locus_tag="ACZPB4_05785"
     CDS             12500..13471
                     /locus_tag="ACZPB4_05785"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001727 - lipid kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol/lipid kinase family protein"
                     /protein_id="HIR1097766.1"
                     /translation="MSERDIKVQAIINPISGVGSKRKIPKMIEGICSKKNCSLNISFT
                     EYAGHASELTRQAIEEGAEYILAVGGDGTVNEIARAMIHSNAILGIIPKGSGNGLARE
                     LHIPMDVKRAIDLIAKGHVTTIDCCRANGQVFFCTCGVGFDAAVSQKFANEKRRGSLT
                     YIKNTIEEYLSYKPEPYELVVDNQTIKEKAFLVACANASQYGNNAFIAPHANIQDGRM
                     DVTILSPFMPLDIAPLAIQLFTKQIDRNSKIKTMKAQQVTIIRQHPGVMHLDGEPIMA
                     DRRIDITVEPKALHVLTPEVVSFTKEVHNLFDEVTRFFDKKLPYIFK"
     gene            complement(13456..14169)
                     /locus_tag="ACZPB4_05790"
     CDS             complement(13456..14169)
                     /locus_tag="ACZPB4_05790"
                     /EC_number="2.1.1.223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_036612898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016430 - tRNA
                     (adenine-N6)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HIR1097767.1"
                     /translation="MANPYFQFKKFTVWHDKCAMKVGTDGVLLGAWASTERCQRILDV
                     GTGTGLIALMLAQRSTAILDAIDIDLDACLQARENIAKSPFANRIQVYQTSLSEYMPD
                     ENIKYDLIVSNPPYFIDSLKCPDTKRNLARHTDTLSLPDLLRDSRKLLAPEGNIALVL
                     PFEQRESLIDIAREESLSPSREAHVSPIPDAPPKRLLIELSATPVAKPKSSHLTLEIE
                     RHRYSEEFTAIAKDFYLKM"
     gene            14258..16729
                     /gene="lon"
                     /locus_tag="ACZPB4_05795"
     CDS             14258..16729
                     /gene="lon"
                     /locus_tag="ACZPB4_05795"
                     /EC_number="3.4.21.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase La"
                     /protein_id="HIR1097768.1"
                     /translation="MNVYMKEKTRVFCQNSFDDLDDNIGIVMPILTECDVDEDFTEGI
                     EKVGDTIPILPLRNMVLFPGVALPVIIGRPKSMRLIKEAVHKKSLIGVVCQKEMGTED
                     PILEDLYTTGVIADIVRVLEMPDGSTTVILQGKKRFELNELTETDPYLSGKITVLEDT
                     KPDKTDREFEALISTIKDLTIKMLGAVAEPPRDLIFSIKNNKNVLYVVNFSCSNIPSG
                     SAEKQQLLLIGDLKERAYRLLFILNREYQLVELKASIQMKTHEDINQQQKEYFLQQQI
                     KTIQEELGGNINELEIKELREKASRKKWPAEVAQVFEKELRKLERLHPQSPDYSVQTQ
                     YVQNIVNLPWNEYSKDNFNLSHAQKVLDRDHYGLEKVKERIIEHLAVLKLKGDMKSPI
                     ICLYGPPGVGKTSLGRSIAEALRRKYVRVSLGGLHDEAEIRGHRRTYIGAMCGRIIQN
                     IQKAGTSNPVFILDEIDKITNDFKGDPASALLEVLDPEQNNAFHDNYLDIDYDLSKVM
                     FIATANNLNTISQPLLDRMELIEVSGYIMEEKVEIAAKHLVPKQMDVHGLKKGSVKFP
                     KKTLQVIVEAYTRESGVRKLDKKIAKIMRKLARKVASDEPIPTSIKPEDLYEYLGAVE
                     YSRDKYQGNGYAGVVTGLAWTAVGGEILFVESSLSKGKGSKLTLTGNLGDVMKESAML
                     ALEYIHAHAAQFNINEELFENWNVHVHVPEGAIPKDGPSAGITMVTSLVSAFTQRKVK
                     KNLAMTGEITLRGKVLPVGGIKEKILAAKRAGIKELILCKENEKDINEIKPEYLKGLV
                     FHYVSDIQQVVDLALLREKVDNPLF"
     gene            complement(16867..17682)
                     /locus_tag="ACZPB4_05800"
     CDS             complement(16867..17682)
                     /locus_tag="ACZPB4_05800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HIR1097769.1"
                     /translation="MKRYIILALCTVMLLGQAVQLAAQKADWKVGIQTWTFHNLTLME
                     TLDKTQQLGMGYAEAFFFQELGAPFPKETYLNYDLSDDDCALLRHEFKKRGIKPIAFG
                     VASYGTNEEWDKFFAFAHKIGAHIVTVEPELNQLDYIESLAKKYDMEVAIHNHPSPCI
                     YASAEVVEKALKGRSPLMGVCADIGHWKRVGEDPLKNLQKLSGRIKVAHLKDLTDKME
                     DATWGTGILPVKAFVNELKRQHFNGLISIEYDDFKSDIQEIRNSLEFLQKCSK"
     gene            complement(17685..19166)
                     /locus_tag="ACZPB4_05805"
     CDS             complement(17685..19166)
                     /locus_tag="ACZPB4_05805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HIR1097770.1"
                     /translation="MESRRDFLKKAAVAAAGLTIVPSKTIAGLGHKAPSDTMNIVGIG
                     IGGKGHPNLVGMKTENIIGLCDIDWKYAKNCFEEFPDAKRYWDWRKMFDELGDQIDGV
                     MVATPDHTHATIAATALTMGKHVYCQKPLTHSVYESRLLTKLAAKYKVATQMGNQGNS
                     GDGVRQLCEWIWNGEIGEVKEVHAWTNRPIWPQGLQRPTEKQRCPKTMNWDLFIGPAA
                     MRPFHEIYTPWNWRGWWDFGTGAFGDMACHVLDPVYQSLKLGYPDRVQGRSTQINTES
                     APQSEVVEFRFPARDNLPKVALPEVKVYWYDGGMLPQRPDLLPDGVDMMRDGLGGCIF
                     VGTKDTLICDCGGFNSRLLSGRVPQVTPYLRRIPNATGYFDGFHEQDWIRACKESPEN
                     RVEGTSNFAYSGPFNEMVLLGVLAIRLQGLNKKLMWDAQNMRFTNISSSDVLKIVTSD
                     DFKVIDGHPYFDTKYAEFNALEAANEYIRHTYREGWSLPEMPV"
     gene            complement(19197..20111)
                     /locus_tag="ACZPB4_05810"
     CDS             complement(19197..20111)
                     /locus_tag="ACZPB4_05810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HIR1097771.1"
                     /translation="MRKISEILCCVAILCCALSACSDKQATVKVSSFNIWLNTLGGKL
                     PPSQTAKVIEASQTDIVGIQEGHIYEEDGIKHDHVPEIAESLGFHLFNQGEGHYILSR
                     YPVVDSTASRYGVKIQVGKDKFCWMFNCHLYYIPYQPYQLNGIPYGDYPFIDTEEEAV
                     RFANEARREEVTRYQKDIQQVMKEGYPVFLTGDFNEPSFLDWTQRAADADIHKIKVEW
                     PATKAFSEIGMNDSYRTIHPDEVSTPGYTWTPVPSEQEILDRLDFVLYSGCKVTDSFI
                     TGESEATSDVVVSPYPSDHRMVTSCFNF"
     gene            complement(20181..21344)
                     /locus_tag="ACZPB4_05815"
     CDS             complement(20181..21344)
                     /locus_tag="ACZPB4_05815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family protein"
                     /protein_id="HIR1097772.1"
                     /translation="MNRKEFFKVSAAASLASLLSPLSAYAEKFESEGKKVKVAVIGCG
                     SVSTQYFPHISKCPYVEIVACCDIKPDRAQKAAKQYNIPKWYKHIDDMLSGSKFDLML
                     TLTDMQVHGELNRKALMAGRNVWSEKPLANSYKEGKELYDLATSKGLRIWGAPAVVNS
                     PQFAFMAEQINKGTLGNLACAHGHYGHEGPSWSAFFYEPLGGSMPDLGVYNIATLTGL
                     LGPAKSVVAMTTIVTPERTVDDKGKIKVREEDNAMIIMEHEKGVLSHIECGFNYFDPY
                     GHLGKGQEKATISLYGSHGNMHMVGYDWAPNGVDLSTMDHPVPQRFVPDTNGYVWQEG
                     ASDISKHMALNTEPRINVEHALHVLEIIEAARKSQATGQRIQLVSKFPWPMVK"
     gene            complement(21366..22142)
                     /locus_tag="ACZPB4_05820"
     CDS             complement(21366..22142)
                     /locus_tag="ACZPB4_05820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-disaccharide hydrolase"
                     /protein_id="HIR1097773.1"
                     /translation="MKKIVSIFLVTIYGMCMVACGSRSSSTEVKDNVLTEEEKAEGYT
                     LLFNGKDFTGWKMFNGGDVKGWQVEDGVIVGYGNGGDVIADTTIKVSTDIVTVKNYHN
                     FQIKWDWKIGAQGNSGFLYHVQEGPKYKAPFETGPEYQLIDDDNYPWVSETGKEGLED
                     WQKTGCNYAMYVPETKQVNPPGEWNSSMVLYKDGYVEHWLNGEKLFSFQEGSEDWKMR
                     RYSGKWEAFPDYGISTTGKLCFQDHGSKVYFKNVKIKDLD"
     gene            22311..23204
                     /locus_tag="ACZPB4_05825"
     CDS             22311..23204
                     /locus_tag="ACZPB4_05825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HIR1097774.1"
                     /translation="MAKIKHGFSGQRLIVYPFYVIEQALNNPLVADLVVHSMGYFPKA
                     ESHYIDRASGCGEYLLIYCTKGEGWYVLDGKRYVVPENHFFILPAEKPHQYGSSEHDP
                     WYIYWAHFKGKKAKYISDQLQGVIPIDMDDNSRIGDRIAFFDELLNVLESGTDEATVN
                     YVNLSFNHLIASFLYVKTYREAKFSKSKAENTFFISLATHFMTENLENKLTLKELASH
                     FGYSESYMYRLFFKETGYAPMNYFLHMKIDRACQLLLHTNMKINQVALKLGFDDPYYF
                     SRIFKKIVGTSPKDYRHSLPK"
     gene            complement(23233..>23553)
                     /locus_tag="ACZPB4_05830"
     CDS             complement(23233..>23553)
                     /locus_tag="ACZPB4_05830"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016407 - acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HIR1097775.1"
                     /translation="LDGAKVRIGNNAFIAPNVGIYTAGHPFDVKQRNEGLEYAFPVTI
                     GDNVWIGAQACILPGVTIGDNTVIAGGSVVTKDIPANVIAAGNPCRVIREITEADRNK
                     YRQP"
     assembly_gap    23554..23653
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<23654..24024)
                     /locus_tag="ACZPB4_05835"
     CDS             complement(<23654..24024)
                     /locus_tag="ACZPB4_05835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016407 - acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="maltose acetyltransferase domain-containing
                     protein"
                     /protein_id="HIR1097776.1"
                     /translation="MKTEKEKAAEGLLYNANHDSELQDEMKRAKCVLFKYNQLPPDQE
                     EEKDRILTSFLGKKGKNTVILSPFQCDYGYNIEIGDNFFANVNLVILDGAKVRIGNNA
                     FIAPNVGIYTAGHPFDVKQRN"
     gene            complement(24089..25018)
                     /locus_tag="ACZPB4_05840"
     CDS             complement(24089..25018)
                     /locus_tag="ACZPB4_05840"
                     /EC_number="1.97.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0043687 - post-translational protein
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HIR1097777.1"
                     /translation="MINKYKVSENRLSIMEIERFAVHDGPGIRTVVFLQGCPLHCPWC
                     SNPESQKRKPHLLHVKNKCIGCGRCEAICPRGNIAIQDHFPVFNRQACVACKACERIC
                     PQNAIKFVGESITSSEIMEILLRDRDYYLNSGGGVTFSGGEAFTQFEGLMDLLIQCKN
                     EKLHTSVETCGQVNLDKIKQALPLIDLFLFDIKHTDKDLLQKETGANLDTILTNLRYI
                     SSKSANKVTIRVPVIPGFNFNENTLREIFMLAKENRIKCVHLLPYHTLGKDKYEQLGL
                     TYPYPCEQMLAKEELFPFKEMGEKMGLEIRIGG"
     gene            complement(25008..27287)
                     /locus_tag="ACZPB4_05845"
     CDS             complement(25008..27287)
                     /locus_tag="ACZPB4_05845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase family protein"
                     /protein_id="HIR1097778.1"
                     /translation="MANFNVEGAQNVEISKKIPCEKPLIVQLEIMERYTAVHKACAAL
                     PKEIREVECLKVLYPTLFRKITNQDLIAGRTDFLPIGFGCVTSLGGVGHYCVFKKLRA
                     FQLQLDETERKRVDALYDYWLDHDLKTQFNKEVLTEDTLGMFIDCEYPMIATARLSGM
                     MLDYPKLLDKGIGGLRSDLLEKLKEQPDNNFYKAGIQCLDIFVDCASHLQQDAREQMA
                     SANMKRQKELERICQALENIKEKKPGTFHEAMQLFWLFALLAGVINYGRLDDYLGPYL
                     VADLKSGRLTDEEAYRYIHSLWTMIENRRTTVNGRIIVGGKGRKHPKEADVFLHIAMK
                     VAKNCRYVEPQFTLRFDKETSEEIWDEALDALGAGATYPTLYNDDVNVPAVMYGMRVD
                     EKTAEQYVPFGCTEFVIQGQSTGTPNICINLLKLLTIYMNDGIDPIDGKRKSGPVSLK
                     KLEEYQTFEEFYDGYKALLDYYLDLSVKAQYHSYEVMNQHVSFLFTSLLTDDCIARGK
                     ALLDGGVRYLGGTNETYGNINTSDSLWVIRDLVFNQKKYTLRQLNDAMLANFNGYEAL
                     RKDCLNCDKYGNDLETADTMANDLYEFVAKGVRNRGIAIGMQYFLIVISNNQLNTEWG
                     NRTAASPDGRLSCMYMNPANNPQGGANKSGPTAMLNSLAKFDAKYHGGSVQNIKFSPS
                     MFNENRAVIKSLFKTYFAKGGCHLMVTVVDKGVLEDAVEHPENYPDLIVRVSGFSAVF
                     VDLSPNIQQELLSRVLYDK"
     gene            complement(27353..28093)
                     /locus_tag="ACZPB4_05850"
     CDS             complement(27353..28093)
                     /locus_tag="ACZPB4_05850"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047465 - N-acylglucosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HIR1097779.1"
                     /translation="MKTNKKELLDSFKGGLIVSCQVQHDDPTFSVDFVVKMAKAAQWG
                     GAVGIRANDPEQIKAIKKEVDLPVIGLWKIWHDDTDVFITPTLEAAKAVWEAGAEIIA
                     LDCTSQITHEGRPAYELLPIVKKEIPEAIIFADVSNYEEAVRAVEIGADIVGPTLYGY
                     TEATKHIEQPDLREFARMCRDFKDKAYVIMEGHIYSPEDAMKCIFLGAHSVVVGSAIT
                     RPHLITKRFTDLLTGYQNNWREAERSKH"
     gene            complement(28104..29069)
                     /locus_tag="ACZPB4_05855"
     CDS             complement(28104..29069)
                     /locus_tag="ACZPB4_05855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HIR1097780.1"
                     /translation="MESTKYYLGLDVGGTNMVAGVVDENHQIIAKESIPTQAGRTIEE
                     ITADMAEVSKKAVLKAGLQMEDISSWGIGMPSYVNPKTNLLVHANCFGWKNVPIYDYL
                     KKHISLPTYIANDANCATYGEVLAGSASQYTDAIMLTLGTGVGGGIIMGKRIYSGADN
                     MGAELGHTKLVYNGERCTCGQKGCLEAYCSSTALIRIMKEALQENKDTLIWKLCGEDE
                     NKVNGEILFEAAKQGDSLAKQIVDDYISKLAAGISTFITIFRPQVIILGGGIAHAGDL
                     LLKPLNEKLHTCTFAAEEIGIPQVIRAELGNDAGIIGAALLEKTM"
     gene            complement(29214..30038)
                     /locus_tag="ACZPB4_05860"
     CDS             complement(29214..30038)
                     /locus_tag="ACZPB4_05860"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HIR1097781.1"
                     /translation="MKTKTVLLFLIVLFSGICRIHAQADFYLMQALGSRYIYNSDYFE
                     ETREMQVYLSGVDGSLKRDSLLAIYVLDAQYPPTFNLFCSTFELTHPNIPCIIVGIFN
                     SNRQSELTPPFTDSLSVKRYDNPGHGKEMLSSLTNEIIPFIQEKYHAGNNRILVGHSL
                     GGTFVTYAMMEHPDLFPYIIAISPNYKYSENMMIDRLRVFTETYQGEKKLYIYLANGD
                     KDKTEEDFKPMIKEACSIIEKNNRIDLRYDSLNIKKHSHTIFEGYYRSLLSITPLL"
     gene            complement(30160..30597)
                     /locus_tag="ACZPB4_05865"
     CDS             complement(30160..30597)
                     /locus_tag="ACZPB4_05865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5606 family protein"
                     /protein_id="HIR1097782.1"
                     /translation="MLKTILSISGKPGLYKLVSHGKNMLIVESLTDNKRVPAYAKDKV
                     ISLGDIAIYTDETEVPLHEVLTSVKNKEEGKTASLVPSKATTDQLRAYFAEVLPSYDR
                     ERVYPSDIKKLLSWYNILINAGITDFTPEDAPAEKEAAEKEAE"
     gene            complement(30809..31390)
                     /gene="coaE"
                     /locus_tag="ACZPB4_05870"
     CDS             complement(30809..31390)
                     /gene="coaE"
                     /locus_tag="ACZPB4_05870"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018231.1"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HIR1097783.1"
                     /translation="MIKIGITGGIGSGKSVVASLLALSGIPVYIADEESKWLTNNSPV
                     IREKLTALFGLEIYTNEGLNKKLLASHIFNNPEQLQQVNQIIHPEVNRHFSAWVERQT
                     SPLCAIESAILFESGFYKVVDISLMVYAPRELRIERALGRDSASREEIERRINSQMSD
                     EEKKDRSDYVIYNDNRQALIPQVGKLLCWLQSQ"
     gene            complement(31383..32396)
                     /locus_tag="ACZPB4_05875"
     CDS             complement(31383..32396)
                     /locus_tag="ACZPB4_05875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HIR1097784.1"
                     /translation="MSRLENIQNSFKSIQAKTKAFFHGDRWKEVLVFFFFALLAFGFW
                     LLQSLQQEYEIELVFPVKYKNVPADIAFNAPEVETITAKVKDKGSVLLNYTFGRSFAP
                     IEVNMKNTKEKNGSVQVSKRQIENDIQKQLIATTALQSFDPQQIDMDFSQRVHKEILV
                     VFNGDIHMEAGFQLSGDIQINPQKINAYATAAILDTLTSVKTAFTEVKKANKNITRTV
                     QLIKVDGVNFDPENVSITIPIEEYTEKTLEIPVSCSHIPPHYTVRMFPAVVKVTCSVP
                     LSRFKGLSEDMFSIHIPFEDLEQNVSGTLPVKLTKKPDWVHTATLLPDKVEFILEHNN
                     KHD"
     gene            complement(32411..32725)
                     /gene="yajC"
                     /locus_tag="ACZPB4_05880"
     CDS             complement(32411..32725)
                     /gene="yajC"
                     /locus_tag="ACZPB4_05880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HIR1097785.1"
                     /translation="MNLLSILLQTPAGGSQWSGILMMVVIVAIFYFFMIRPQQKKQKE
                     IQKSREALKTGDKVITAGGIYGKIKEIGDTYMLIEVADGVRIRVDKTSIFASAEDAQQ
                     QK"
     gene            complement(32788..33714)
                     /gene="nusB"
                     /locus_tag="ACZPB4_05885"
     CDS             complement(32788..33714)
                     /gene="nusB"
                     /locus_tag="ACZPB4_05885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HIR1097786.1"
                     /translation="MINRILIRIKVLQIVYSYYQNGNGDLKVAENELLFSLQKSYDLY
                     YYFLLLIIEVTNLQRRILDTRKCKYMPTDEELNPNTRFIDNRFVAQLAENDTLKKYVD
                     EQGLSWSNDEEFIKNVLDTILSSEIYAEYLKNEEDSYETDREFWRQIFKKIICGNEMI
                     EEYLEDKSIYWNDDIEIVETFALKTIKKFEEKKGSKQALLPMFKDLEDKAFAIKLFRQ
                     SLLKGKEYRERIDKHMKNWETERIANMDLIIMQVALAEILSFPTIPINVTLNEYIDAA
                     KYYSTPKSGTFINGILDSIVNELKKEKLLLKD"
     gene            33938..34327
                     /locus_tag="ACZPB4_05890"
     CDS             33938..34327
                     /locus_tag="ACZPB4_05890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PUR family DNA/RNA-binding protein"
                     /protein_id="HIR1097787.1"
                     /translation="MEESRNKKHVEGGDREILYSKAIKAGKRIYYLDVKRNLKDDLFV
                     AVTESKKIQSKDGLQISFEKHKIFLYKEDFEKFMEGMQDVISYIKNSNLKKSAEDVVE
                     PEEEETIHGDSPEEDMASGDIKLDIEF"
     gene            complement(34435..34605)
                     /locus_tag="ACZPB4_05895"
     CDS             complement(34435..34605)
                     /locus_tag="ACZPB4_05895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005810660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HIR1097788.1"
                     /translation="MAYVISDDCIACGTCIDECPVGAISEGDKYSINPEMCTDCGTCA
                     DACPTEAIHPAE"
     gene            34758..35459
                     /gene="porT"
                     /locus_tag="ACZPB4_05900"
                     /gene_synonym="sprT"
     CDS             34758..35459
                     /gene="porT"
                     /locus_tag="ACZPB4_05900"
                     /gene_synonym="sprT"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IX secretion/gliding motility protein
                     PorT/SprT"
                     /protein_id="HIR1097789.1"
                     /translation="MRRLLLILYVVSLATMGAMAQKERVRNQPYADLKWLHLGFHVGI
                     HSQDLLLTHTGVMTNGETWFAEIPSYSPGFSVGVIGDMYMNPYFNLRFTPSIHFGDKK
                     FKFREQATGEEFITNVRSSYLNFPLDVKYTALRLNNYRPYLIGGIYGSVDIGRKKGNP
                     ILLKSTDFGFEFGLGCDIYLPYFKLCPELKFCFGLVNLLEKDRPDLVDQANIKYTDAL
                     SKATSRMVILTFNFE"
     gene            complement(35446..36279)
                     /locus_tag="ACZPB4_05905"
     CDS             complement(35446..36279)
                     /locus_tag="ACZPB4_05905"
                     /EC_number="2.7.7.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004605 - phosphatidate
                     cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0016024 - CDP-diacylglycerol biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HIR1097790.1"
                     /translation="MKNLITRALTGIIFVAVLVGAIYFHSYYFLTVFGLITGLSLWEF
                     YGLVKHYENAAIKRFVSSLGGAYLFAATFGYANGLVGGNIFLPYLLFLMYTMITELYD
                     KASNPINNWALTLFGQIYCAGSFSLLNFITSVPNTPGEIVHIPYFALAIFVFVWVNDT
                     GAYLVGSMLGKRRLFERISPKKSWEGFYGGLAFVLITSQIFAWFMPATNWYTWLGLAG
                     TIVVFGTWGDLIESLMKRTLGVKDSGHVLPGHGGMLDRFDSVMMAIPAAYIYIELFIR
                     N"
     gene            complement(36422..38476)
                     /gene="ftsH"
                     /locus_tag="ACZPB4_05910"
     CDS             complement(36422..38476)
                     /gene="ftsH"
                     /locus_tag="ACZPB4_05910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HIR1097791.1"
                     /translation="MENKNDMFNKTPKSGKPKMFRFNLYWMYGLIFIMLVALYMTNDS
                     SGTKELGWTEFQKLAQENVFDKMTVYNKKNLVEATVKNGKTEQVFGNMDVSKIGVSPK
                     VYVKIPSADKFSDFYDKAVADSHIDTQVRFEEGDDAIWNFLVSFGPIILLIGVWMFLM
                     RRMSGGTGAGPGGVFSVGKAKAQLFDKDNDRKVTFKDVAGLAEAKQEVEEIVSFLKNP
                     EKYTELGGKIPKGALLVGPPGTGKTLLAKAVAGEANVPFFSLSGSDFVEMFVGVGASR
                     VRDLFRQAKEKSPCIVFIDEIDAVGRARGKNANMNSNDERENTLNQLLTEMDGFGSNS
                     GVIILAATNRADILDKALLRAGRFDRQIHVELPDLNERKEIFGVHLRPIKIDESVDAE
                     FLARQTPGFSGADIANVCNEAALIAARNGKKFVQKEDFMNAVDRIVGGLEKRSKITTE
                     EERKCIANHEAGHATLSWLLEHANPLVKVTIVPRGKALGAAWYLPEERQITTREQLQD
                     EMCATLGGRAAEELVLGKISTGASNDLERVTKQAYAMVVYFGMSDKLPNLNYYDSTGQ
                     DWGFTKPYSEETAKLIDTEVQKIINEQYDRAKRILSENKEGHSKLAQVLLDREVIYSE
                     DVEHIFGKRAWISRSQEILELQEKANGKNKENADKEAKADATMENVTDTPTEENKTGK
                     IA"
     gene            complement(38507..38866)
                     /gene="rsfS"
                     /locus_tag="ACZPB4_05915"
     CDS             complement(38507..38866)
                     /gene="rsfS"
                     /locus_tag="ACZPB4_05915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HIR1097792.1"
                     /translation="MDQTKELVKTIVEGLQEKRGKNIVTVDLSQTSGAICQYMVICEG
                     NTPTQVSALSDSVWDFARKNANEKPLSIDGTQGAQWIGMDYGTVLVHIFLPEQRAFYN
                     LENLWADSKVIQVPNID"
     gene            39154..39224
                     /locus_tag="ACZPB4_05920"
     tRNA            39154..39224
                     /locus_tag="ACZPB4_05920"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:39186..39188,aa:Gln,seq:ctg)
     gene            39258..39328
                     /locus_tag="ACZPB4_05925"
     tRNA            39258..39328
                     /locus_tag="ACZPB4_05925"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:39290..39292,aa:Gln,seq:ctg)
     gene            complement(39391..40707)
                     /locus_tag="ACZPB4_05930"
     CDS             complement(39391..40707)
                     /locus_tag="ACZPB4_05930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1097793.1"
                     /translation="MSKIGLIIKREYLRRVSKKSFILLTFLTPFLFAALAFVPLWLSS
                     IKGDEVHTVAILDATGKYAPLFEDTESYRFINGDKDMDKYRQMSEKEIFAFLNISDDL
                     QKNPKNATLYSKKQIPADLSRLVNMTLKKQIESDKLATFNIPNLQEIIKESKVDFNIQ
                     TIKWGDDGSEKQSSSVVASITGVIFTMLIYMFILIYGGMVMQGVMEEKTNRIIEIMIS
                     SVKPFDLMMGKIIGIGFVGLTQVFLWVVMTFILITGGTFFLGGGMESEILQSSMALNT
                     TPNMTAIAAQQHGNEWIEMLHTINFTEIGILFIAYFIGGYLLYSSLFAAIGSAVDGQE
                     DTQQFMLPVTLLLVFALYAGIYSMENPDGPLAFWCSMIPFTSPIVMMVRVPFEVPLWE
                     ILLSIGFLYISSIGFTWFSAKIYRVGILMYGKKPSIKEMSKWLRYK"
     gene            complement(40704..41576)
                     /locus_tag="ACZPB4_05935"
     CDS             complement(40704..41576)
                     /locus_tag="ACZPB4_05935"
                     /EC_number="7.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1097794.1"
                     /translation="MNFLETENVVKQYAGHLALNKVSIQVPQGTIFGLLGPNGAGKTT
                     LIRIINRITAPDSGIVRFNGHESSPEDIYQIGYLPEERGLYKKMKVGEQAIYLAQLKG
                     LSYPEARSRLTRWFEKFDIMPWWNRKLEELSKGMQQKVQFIITVIHEPELLIFDEPFS
                     GFDPVNADRLKQEILELKAAGHTIIFSTHNMSSVEEICDEIALINRSEVVLSGNVKEV
                     RERFKSNTYILNVRKETGGIEELRIRKEENISNSDWLTRLASQYEILSFTEEIPSMND
                     IFINTVSGTNTSKV"
     gene            complement(41590..43707)
                     /gene="dnaG"
                     /locus_tag="ACZPB4_05940"
     CDS             complement(41590..43707)
                     /gene="dnaG"
                     /locus_tag="ACZPB4_05940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed RNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HIR1097795.1"
                     /translation="MIDQPTIDRILDAANIVDVVSEFVTLRKRGINYVGLCPFHSDKS
                     PSFYVSPSKNICKCFACGEGGTAVHFIMKHEQLSYFDALRFLAKKYNIEIQERELTEK
                     EKQIRSDRESMLIVNSWAGQYFSTLLHEHVEGKSVGMRYFAERGLREDIIRKFQLGYS
                     LDQRDALYKTAIKAGYKKEFLEKTGLVIAYDNGNVNDRFRGRVIFPVHTLSGKVVAFG
                     GRVLKKDEKTAKYVNSPESEIYHKSNELYGIYFAKQAIMKQDRCFLVEGYMDVIGMHQ
                     VGVENVVASSGTALTQGQIRLIHRFTNNITVLYDGDAAGIKAALRGIDMLLEEGMNVK
                     VVLLPAGEDPDSFARSHSASEFAEFISQNETDFIRFKTKLLLAEAGSDPIKRSALISD
                     IIRTVAIIPDNIARSVYIRECSTTMEIDEQVLLNEVNKIRLNKEENQAAKSVRNTPPV
                     QSPVNTIPEYPDFPGYQPYTQEEANTLLPENIPPPPPEDYIPEEEAGPPPTPPYEVPT
                     APNIQVQPKRSPFEAYELALLRYIVRYGERVLYDYVDEETNEHVIMRVADYIRFDLER
                     DDLTFYTPAFKQMLDEAAEHCQNEGFMASRYFLAHPDPNISRLAANLISDKYQLSKYH
                     TKFRELEQEEDKLDYLVPREIYSMKDAYILYKIKDIQAKIKEAQNKGDMELIFDLMKQ
                     NAHLNEIKNVLCKELGERIVLKM"
BASE COUNT        11155 a         9471 c        10039 g        13065 t
ORIGIN      
        1 aaggtatgat ttcaaatcgt cgcgcctaaa aagtagtatc taatagacta tatttcaatt
       61 atttcaaaga actatttatc cacttttacg ggacagtaat gagtttgatt aaaagtttat
      121 ttatcgcaaa gtaagtatat taatctcatt taagcaaacg atacgcggtt taaatgagaa
      181 ggtacgaaaa atattgctta tctttgcatt atacattaat atccaattgt gtaatgaata
      241 aacaatctgt catatctctt cttcggaaag caaagcagcc tttgtcgcag agttgcggtg
      301 taaagcagtt ggggcttttt ggctctactg ttcgtgagag caatacggaa agtagtgatg
      361 tggatatatt gatcgacttt gaggatgata aagagactta ttccaatttc cttttggctt
      421 gtgagatatt agagaagctt tttgacagat tgaaagtgga catagtcacc cttaaagggt
      481 taagcccttt tattggccag cagatattaa aggaggtaga atatgtgtaa gacccctatc
      541 gcttatttgc tgcatagtag ggctttatgc gattttggct gtgtgcgacc tctgttttat
      601 gggagaacca tggtgccgat acctgcataa cgtggggatt atcgtggggt gcgtgtgctt
      661 tatcagcctc acggcgacct gtttggagcg agggctttgt cgggtaagcg gttttctggc
      721 ggggagcagc ttctttgttt atgcttatca tgggatgccg ttggcgttgg ctatcaaggt
      781 ggtggttcgg tatctccctc cggggtctga gttagaggtg ataggcttgt atttgggatc
      841 tgcctgtgtg gtgataggga tcggactcgc tttgtatggc gggatgaggc ggtgtgtccc
      901 ttccttttta ttgctgatta ctggcggacg atagttctca tcactaaaat ggcttgtctg
      961 cgtaattcgc ttattcgtgg ctttttgctt ggaatgggcg cttttcgctg acaagtcatt
     1021 cctttgaata ggctgaaata gcgggaatag aggggagaaa agagaggatt tggttgtctt
     1081 ttcatgctgc ggataggcat tgtaaggttg ttacgatcca gttgtaggat gtttacggcg
     1141 gcgttgttag ttgctttcga ctacgaatgc tattgttttc ggagcgaaac actattgttt
     1201 tcgagtgaaa agtctattgt tttcgaataa gaagtctatt gtttgtatgt ttgagggtga
     1261 taagagacgg gaatcctcgc tagaataaaa gctccaaaaa cgatatatcc ttggaagata
     1321 actaattgcg gatttttatt ctcaaatttg gaagccgact gtactctggg gcgaaatatt
     1381 cgattctctg gagctttaga atacaaaatg tcagaatgtc aaattgggcg atcttctatt
     1441 attaacaaag gaaatctcat tatcttaggg caatgtcata tgttgtagag acggggcgtg
     1501 ccccgtctcc cgtatcatgt gcgatggatt catgtttctt tggctatgga tgaaatttgg
     1561 tatggttgcc ttgtttttat ctgaataata aggctggatt ggaaataaat atctactttt
     1621 gtgctctaaa acattaaagt aaacgaaaat agaaagatgg ctgcaacgaa acgaatgaaa
     1681 cgtgccttgg tctctgtgtt tcacaaagac gggctggacg aaatcctaaa gaaattgcat
     1741 agcgagggtg tgagctttgt atcaacaggt ggtactcaat catttatcga gtcattgggt
     1801 ttgccttgtg atgcggtaga ggacttgact tcttatccgt ctattttggg cggtcgtgtg
     1861 aagacgcttc atccgaaggt gttcggtggt atcttggctc gccgcgagaa cgagaatgac
     1921 cagaaacaat tagccgaata tgagatcccg gagatcgact tggttatcgt tgacctatat
     1981 cctttcgagg agactgtcgc ttccggcgct gaggaacaag cgattattga gaaaatagat
     2041 ataggcggta tctctttgat acgtgccgcc gcgaagaact tcaaggatgt ggtaatcgta
     2101 gcttccaagg ctcaatacca gccgttgatg gatcttttga acgagaaggg cgctgagaca
     2161 agcatcgagg atcgtagatg gttcgccaaa gaggcgttcg ccgtttcctc gggttacgac
     2221 tccgctatct tcaattattt tgatggccgc gaaggttccc atttccgtgc aacggtagat
     2281 agcccgatgc atttgcgtta tggcgagaat cctcatcaag ccgctaagtt ctatggtaag
     2341 tttaacgata tgttcgatca aatccatgga aaagagattt cttacaacaa cttattggat
     2401 atcgacgctg ccgtgaactt gatcgatgag ttcgacgagc tgacgttcgc tatcttaaaa
     2461 cataataacg cttgcggtat cgcttcccgc ggtaatgtgg ttgaggcttg gaaagaggct
     2521 ttggccggtg acccagtttc cgctttcggt ggcatcttga tcacgaatac tacgattaac
     2581 aaggaagtgg ccgaggagat ccataagatc ttcttcgagg tgattatcgc cccggcttac
     2641 gacgctgacg cattggaggt acttcaacag aagaagaacc gtatcatctt gatccgtaag
     2701 gattgcaaga cttgcccgat gcagttccgt tctttattga atggtgtctt gatgcaggag
     2761 aaggacttga gcatccaagg taaggctgat ttggagccta tgacggataa gcagccgaca
     2821 gcctcggagg ttgaggacct gttgttcgcc aacaaaatcg tgaagaacag caagtccaac
     2881 gcgatcacct tggtgaagaa caagcagctt tgcgccagcg gtatcgggca gacctctcgt
     2941 gtggactctt tgagacaagc catagagaag gctaaatcat tcggcttcga cttgaatggc
     3001 gccgtgatgg cttccgacgc tttcttcccg ttccccgatt gcgttgagat cgcagaccaa
     3061 gcaggtatca cggccgtaat ccagccggga ggctctatca atgataagtt gtctgtcgag
     3121 tactgtaacc aacatggttt ggctatggtg aagacaggtg ttcgtcattt taaacattaa
     3181 taataagact aatgggattg ttttctttca cacaagaagt tgccatagat ttgggtaccg
     3241 ccaataccat tatcacgtgt aatgataaga tggtggtaga cgaaccttcg gtgattgctt
     3301 tggatgctcg ctcggacaag gtgctggctg tcggtaaggt ggcccgtgag atgtacgaga
     3361 agacgcaccc gaatattcgt accgtacgac cgcttcgtga gggagttatc gcggatttct
     3421 acgctgccga gcaaatgatt cgcggcttta tcaagatggc gagcggaagg aagcgctggt
     3481 tcgctccatc cttacgtatg gtgattggta tcccttctgg tagtacggag gtagagatac
     3541 gtgccgtgcg agactctgcc gagcatgccg gtggacgtga tgtgtacatg gtttttgagc
     3601 cgatggctgc cgctatcggt gtcggtatag atgtcttggc ccccgagggt aatatgatcg
     3661 tggatatagg cggtggtact accgagatcg ctgtcatatc cttaggtggt atcgtgtcga
     3721 ataaatcaat ccgtatggcg ggtgacgatt taacggctga tatcgtggag tatatgcgtc
     3781 gccaacacaa cgtgaaggtg agtgagcgta tggccgagcg tatcaagatc aacgtgggtt
     3841 ccgcgcttac ggtattggag gacgctccgg aggattacgt ggttcacggc ccgaatcaga
     3901 tgactgcctt accgatggag gtacccgtct cttatcagga gatcgcccac tgtttggata
     3961 agtctatctc gaagatcgag gcggctatct tgagtgcctt ggagcaaacc cctcccgagt
     4021 tatatgccga tatcgtgaaa aacggtatct atttggctgg cggtggcgct atgcttcgcg
     4081 gtttggataa gcgcttgcgg gataaaatga atatccagtt ccatatcgcc gaggatccgt
     4141 tgcatgccgt ggcgaaaggt acgggagtcg ctttgaagaa tattgagaag tttaatttct
     4201 taatccgata agagtaaata attgagaatt gagaattgaa agttgaaaat tagcgagccg
     4261 ataggtctgg ttcttttcaa ttttcaattc tcaactttca gttttcaatt cctatgcgta
     4321 agttactaga attcctgatc gggaagaggc attggttttt gttcattctg cttgaggctg
     4381 tttcgttgat gttggtctat cgtaataacg cgtaccaacg gaatattata ttcagctcag
     4441 cgaatgtcgt gacaggatat atcgcctcga tatccggatc tgtcacttct tatttgaatc
     4501 ttcgggatat caataaggag ttattggagc gtaacggaca gttggaattg caaatgctgg
     4561 atctgcaaga tcagttagat gcgctgattg cggatacggt tagttttaag ggatttgcgc
     4621 cggattcgac ggagcaattt ccttattcgt ttgtcgtggc ggatgtagtg aacaacagtg
     4681 tcacgcattt gtctaattat attaccgtgg ataaagggaa gctggacggg atcatgcccg
     4741 atatgggagt tgtctcggaa cgaggtgtgg tgggtatcgt atcgacggtt tccgatcatt
     4801 tctccgtgat cattccgttg ctgaatccta agttccggtt gagttgtaag gtattaggta
     4861 gtagttattt cgggtcatta agctggaatg gacgcaatac gctgtacgcc aacctcgatg
     4921 agttgccgcg ccatgtggag ttccagaaag gcgatacgat cgtgacgagc ggttactccg
     4981 ccgtattccc ctcgggtatt atcgtaggta cggtcgctga tttcgagaaa caacacgatg
     5041 ataatttcta ttcattacag gtcgagctgg ctacggattt tcaagcgttg aacaacgtgc
     5101 gtattatcaa gaatttccgt cagacggagc aaattggtgt agaacaagag gcgaaaagaa
     5161 atgattaata atttactgcg tggtttcata tatttcgtgg tgtttgtgtt gattcaggtc
     5221 ttgatcttga acaacattca tttcttgcgg atcgctaccc cgtttctgta tctctatttc
     5281 attattaaga tgccggtcgg tagctcacgg acgcaagtcg ttttcttctc tttcatagcc
     5341 ggggtggtta tcgatacatt cagcaataca ccgggtatgc atgcggccgc ctgtacattg
     5401 gcgggatttt gcagggagcc gttaatccgt gtattcatgg ggaaagattt gccggaaggt
     5461 atttacccgt cttgtaagac ctttggtttc ggaggctttt tccgatatgt gttatcgttt
     5521 gtgttaatac aacatacgac tctttttgtg attgagtcgt tgactttatt tgacccgttg
     5581 tttctggttg tccgtatcct ctcgagcgtg gtgatgacaa ccttattgat ttgtacggta
     5641 gaagcattca atatagagtc tcagaaaagt ggagaataat accaagtatg agtttgagaa
     5701 caggcgctat gtcttaggtg gggcggtgat cctgttggtt atcatcttta ttatccgttt
     5761 gttcatcctt caggtggtcg acaacgatta taaagcttgg gcggatagta atgctttctt
     5821 gaaaaagacc ttatatcctt cccgaggcat gatgtacgac cgtaatggta aattattggt
     5881 ctataaccag cccgcttacg acgtgatgct tatcatgcgt gagatacagc ctttcgatac
     5941 cctcgatttc tgcgatgtgc tgggcatcac gaaagagcaa tttctcaaac gtatagcgga
     6001 tattaagaac cggcggttaa atcccggtta ttcttcctat gtccctcaag tatttatgaa
     6061 ccagctttcc gcgcaggaat atggcgtgtt gcaggagaag ttatacaaat ttcccggctt
     6121 ctatatacag aatcgcacga tccgccaata cgagtatccc aatgccgctc ttgtgctggg
     6181 aaatatcggc gaggtaaacc ggaaagatat agagaatgac tcttattata cacaaggcga
     6241 ttactccggc aggaccggga tcgaacaatc gtacgaggaa tatttgcggg gcgtgaaggg
     6301 tgtcgagatc ctgttgcgtg acgctcacgg acgtatcaag gggcgatacg aggaaggcct
     6361 gcacgatatc cagccggaat ccggcaagaa cttgaaatta tccttggata tggacttgca
     6421 ggcttatggg gagaagttaa tgcagaataa attagggggt atcgtgatga tagagccgga
     6481 gacaggggag gtactttgta tggtttccgc tcctacgtat gatccgagta tcttgatcgg
     6541 gcgccagcgg ggaaagaact acgtggcttt gcagaaggac ccgttgaaac ctttattcaa
     6601 ccgcccgctc atggcgcaat atccccccgg atctacattt aaaccgaccc aaggtttgat
     6661 attcttgcaa gaaggggtga ttactccgga aactcaatat acctgtgcgc atggatacac
     6721 cttccggggt ggtaagccgg cttgccacgg gcatccgtct cctctgaatc tggtcggggc
     6781 gttggcgacc tcttgtaact cttttttccc ttggggactg catgatatga tcgacagccg
     6841 gaagcgatat ccctcggtac aggaggcttt tgaggtttgg aagaatcaca tggtctcaat
     6901 gggatatggc tataagttgg gaattgatct tccgggagag aagcgagggt tcattccgaa
     6961 tagtaagttc tacgataagg tgtaccgggg acgttggaat tccagtacgg ttatctcgat
     7021 cgctatcggt cagggtgaga tattggctac gcctttgcaa atctgtaatt tggcggctac
     7081 tgtcgctaat cggggatatt atattactcc gcatgtcgta aaagagattc aagacactcc
     7141 gctggataca ttatatagta agaggcatta tacatcggtg gatacgcatt attatagtta
     7201 tattgccgag ggtatgcgag gggctgttac gggaaccgct tatggtggaa cctgtcgtgg
     7261 ggcggcttta ccggatatcg aggtttgtgg aaagacggga acgtcggaga atccgcatgg
     7321 taaggaccat tctattttta tgggattcgc tccttatcaa aagccgaagg tcgccattgc
     7381 cgtgtttgtg gaaaacgccg gattcggtgc tacctatgcg gtgcctatcg gtaaattgat
     7441 gttggagaaa tatttgaaag gagaaatatc cgaggctaac aaggcgacgg aggaatatat
     7501 tatgaatgcc gtaatactac cgaacaatgc gctataggaa aacggaaata tggaagtcgg
     7561 tagactggat taccattttg ttgtatttga ttatggtaat cgccggttgg tttagtattt
     7621 gtggggcgag ctacgagttt gataacgttg gcttgttcga cccgtcgggc cgtccgggga
     7681 tgcagatgat ttggatcggt acctcactcg cccttatttt cgtcatattg atgctggaaa
     7741 gtgacttctt cgatatattc gcctatctga tctatgcgtg cgtgatcgta ttgttgatcg
     7801 ccactatatt tttagcacct aatatcaagg gatcgcattc ttggctcgta ttgggaccta
     7861 tccgtttgca accagcggag ttggctaagt tcgctaccac tttggccgtg gcgaagttta
     7921 tgaatggcta tggctttaag ctaacgacgg tcaagaattt ctcaatcact ttgttcttga
     7981 tcttcttgcc gatggtttgt attcttttac agaaagagac ggggtcggca ttggtttact
     8041 tggcattctt cctgatgtta taccgggaag gaatgactgg atatattttg ttgataggag
     8101 tttgtgcggt cgtctttttc gttacgggaa tgaaatattc agaggtgatg gtgggtatta
     8161 ccccattggg tgaattaatc gtctcttgcc ttgtcttatt aataaccatg ggattagttg
     8221 ggagtgtccg taaggattat ataagcgtta agatcatgct tgggggaatt gcttcgacat
     8281 tcttgatcgg gtatgtcgtt tctttgtttg tcccggtaaa cttcgcttgg atatcgatag
     8341 gcttggtagg agccgcgtca atctatttat tctatttatc cattcgaaac tgggtatggc
     8401 attatgcgtt aatcgctctg ttcgctttag gttctatctg tttcctattt tctgtggatt
     8461 atgtgtttaa tgacatattg gaacctcacc aacaaattcg tattaaagtc tctttaggct
     8521 tggaggatga tccaagcggg gcggggtata atgtgaatca gtccaagatc gctatcggtt
     8581 ccggaggatt atccggaaaa ggattcttga atgggacgca gaccaaattg aagtatgtgc
     8641 cggaacagga tacggatttt atcttttgta cggtaggcga ggagcaaggc tttttgggag
     8701 cctctgccgt attgatcgta ttcggacttt ttattcttcg tctgattgta ttggcggagc
     8761 ggcaagataa tgctttcggg cgagtctatg gctatagcgt agcctccata ttctttttcc
     8821 atctggcgat taatgtcggc atggtgacgg gattgactcc ggttatcggc attcccttgc
     8881 ctttctttag ctatggaggt tcctcgcttt ggggatttac gatcttattg tttatttttc
     8941 ttcgtttgga cgcttctcgg aaggagcgtt agtggaagaa ggtaagaccc gtaagccgat
     9001 ttcctgaatg cccggaagtt ggtcgttacg catcccctgc cggaagctaa aggtatattg
     9061 ccctttaacg gggaaatagt aagcagaccg tatcgggaaa ctggattgaa acagggagat
     9121 cccgtcccca taccatttcc caaactcatc agctaacata cattcgatcg tatccctttt
     9181 taaaggacct atcggaagtt cctcgctgca aaatacccat aggttctgat acggatacat
     9241 attattgttc cgtacttcca aggttaggtc gtacggaacc gatatatcct caatcaagaa
     9301 agtgaaatag tactccttat tcttctccca cgaggtgttc tggatagctt gatactgatc
     9361 gtatacagct tcattctcgc aagagaagca taagaagcat gttacacagg cggcaatgaa
     9421 ctttttaagc ctcaggcttt gtctctggcc tattctccgt tttatcaggt ctggcctgtt
     9481 tgatcggttg ctgaggtttg tcattattcg caggcttgtc attgttggat tgcttatcgt
     9541 tattagctct cggcctttgt ttcgggcgat tgtttcggtt gctctccctg ttattatcac
     9601 ggttgttctc ccgattctcc cgactgtttt cccggctatt atctttgtta ttctcccggt
     9661 tattctctct gtcccggtta ttctcacgat tgctattcct attatttcct ccgttgcggc
     9721 gattattgcc accggctccg tttcctccgt tgttcttatt ctcagaaaca ggtgcgtcgg
     9781 tgttggtaac tgccgtcgcg gtggtgttag ctccgttccc gtttccattg ttctcgccat
     9841 tattcttgtt ggcaggacgt tttttctttt tctttttaac agagtcgaaa cgtgtgacgc
     9901 tttcttgccc aagaatatct tgagcgtctc gtttcggtgg ttgtggcttc gtatccgcct
     9961 ctagagatat cggcttcatg cctttcttat tcatgttaat gacatcgaaa gcacggcttg
    10021 ccggaatcgt gataagatta gccgcaaatg atttatccgt agaataggta atttcccgtt
    10081 tgaaaatatc cgtcttgaaa tgatagtaat tattatcttt ggtctccaag acaatttccc
    10141 gggaaggaag gcgtttctgg gcttccacat atgtatctac ctcataattg atacaacatt
    10201 tcaatttagc gcattgtccg gccaatttct ggggattcat ggaaatatct tgataacggg
    10261 cagctccggt agcgaccgat acaaaacttg tcatccaact ggaacagcaa agttctctac
    10321 cgcaagggcc gataccaccg atacgtccgg cttcttgacg agcaccgatc tgcttcatct
    10381 cgatacgaac acgaaaagcc tccgctagca ctttaattag ttgacggaaa tctacacgtt
    10441 catccgctat ataataaaag atcgccttat taccgtcacc ttgatactct acatcaccga
    10501 ttttcatatt caatcctaaa tcggccgcga tttgccgcga gcgaatcatg gtggcatgtt
    10561 cctttgcttt tgcttcctca tatttctcga tatcggtcgg ttttgccttt cggtaaatcc
    10621 gtttaggctc ggcttccgtg cgcacattgt tcttcttcat ttgcagcaga accaatttac
    10681 ccgttaaaga aaccgtaccg atatcatgac cgggacttgc ctctacggct actatatcac
    10741 ctttttccaa aggtatttta gcactattca agtaataccc tttgcgggta tttttaaatt
    10801 gaacctctac gaaatcagtc gagccttccg cgtcgggtac atcgcacaac caatcatagg
    10861 tattcagttt attgttttgc cttttgctgc aacctttgca gcccatgtgg ctacttcctt
    10921 tatctaatat gaaatccatt tatttttaat ttgtaagagg gccatcgaca taaccaccca
    10981 atttatctaa atatgcaaaa atagtgattt attcccattc aaaatcatag ttatgatttt
    11041 ttcagttata aaaaaagacc cgaagatagg tgttatacct aaccttcggg ccttttctta
    11101 tatatttaca cgattagtct accaacccat ggctcttgaa taccttgtgg attgtctcca
    11161 aagcgtaatc tagttgctct ttcgtgtggg tagccataag ggagaagcgg atcagtgtat
    11221 cctcggaagc aactgcggga gctactaccg ggtttacgaa gattccggcc tcaaataatt
    11281 cttttacgat aaggaatgtc aagtcgttgt cacggataaa caacgggatg atcggggtag
    11341 aagtatgtcc gatctcacaa cccatgttac ggaaaccatc caatgcgtaa tgagtcaaat
    11401 cccataaatg ttggatacgt tccggttcgc ttaacataat atctaatgcc gcgttcgctg
    11461 cggcagtagc ggcaggcgta ttgcttgcgc taaagatata ggaacgggag tggtgacgta
    11521 agtaattgat aaccggttcg tctgatgcga taaaaccacc gatagaagcg aaagacttac
    11581 tgaaagttcc catgatcaaa tcaacatcgt tcgtaacgcc gaagtgatta caagtaccgc
    11641 ggccatgatc accgaataca ccgataccat gagcctcgtc aaccattaca cttgcgttat
    11701 atttctttgc gagagctacg atttccggta atttagcgac atcaccttcc atgctgaaga
    11761 caccgtcgat aacgataagt ttcaccttgt ctggctcgca tttctggagt tgtttctcca
    11821 aggagtccat atcgttatgc ttgaatttca atttcgtgga gaaagaaaga cgatgtcctt
    11881 cgataatgga tgcatgatcc aactcatccc aaaggatata gtcctcacgt ccggtgatac
    11941 aggatacaac acctagatta acttggaaac ctgtagagta tacgatggcg tcttctttac
    12001 caacaaattc tgctaaacgt ttttccaact ggaggtgtaa gtccaacgtt ccgtttaaga
    12061 aacgtgagcc ggcacaacct gtaccatact ttttaatggc ctcgatcgct gcttctttta
    12121 ctttaggatg attggttaat cctaagtacg cattagaacc aaacatcaag actttcttcc
    12181 cgctgattag aacttccgtg tcctgatcgc tctggatttc cctgaagtaa ggatagattc
    12241 ccattgccat ggctctttga ggagcgtcgt actttgctag tttctcttgt aaaagtttca
    12301 tattattata aaagagaatg atttatctcg ctatttattt attctaataa agaacacagg
    12361 ttcgccgcgt acataatcct atgtttcggc aaatccagcc gcaaaagtag taaaaaaata
    12421 acttatagta gtcgaaatgc tttaaaagtt ttataaaagc attatttttg tcctctcaaa
    12481 taaaaaagaa gaagtgagga tgagcgaacg ggatataaaa gtacaagcta tcataaaccc
    12541 tatatcaggt gtagggtcga agcgcaagat acctaagatg atcgaaggga tctgctcgaa
    12601 aaagaactgt tcgttaaaca tttcttttac agagtatgca ggccatgcca gcgagttgac
    12661 tcggcaagcc atagaggagg gagctgaata tattttggcg gtaggcggtg acgggacggt
    12721 gaatgagata gcgagagcta tgatccattc gaacgcgatc ttaggtatca tcccgaaagg
    12781 ttcgggcaat ggcttagcta gagaattgca cataccgatg gacgtgaaaa gagctatcga
    12841 tctgatcgcg aaagggcatg ttacgacgat agattgctgc cgggcgaacg gacaggtctt
    12901 tttctgtacc tgtggagtcg gttttgatgc cgccgtcagc cagaaattcg cgaatgagaa
    12961 acggcgcggc tctcttactt atataaagaa tacgatagag gagtatctga gctataagcc
    13021 tgagccttat gaattggtgg tggataatca gacgatcaag gagaaggcgt ttctagtcgc
    13081 ttgcgcgaat gcttcgcaat atggtaataa tgcgtttatc gctccgcacg cgaatataca
    13141 ggacggacgg atggacgtta cgatcttatc cccttttatg ccattggata tcgctccttt
    13201 ggccattcaa ttgtttacca aacagattga tcggaatagt aagattaaga cgatgaaagc
    13261 ccagcaagtc acgattattc gccaacatcc gggcgtgatg cacttggatg gagaaccgat
    13321 catggcagat cgccgtatcg atattacggt ggaaccaaaa gccttacatg tgctgactcc
    13381 ggaggttgtg tctttcacca aggaggtaca taatttattt gacgaggtaa ctcgcttctt
    13441 cgataaaaag cttccttaca ttttcaagta aaagtcttta gctatagcgg tgaattcttc
    13501 gctatatcga tgccgctcga tttctagggt cagatgagac gacttgggct ttgctaccgg
    13561 cgtcgctgag agttctatta ataaacgctt aggaggggcg tccggtatgg gagaaacgtg
    13621 ggcttctctc gatggagaca aagactcttc tcgagcgatg tctattaaag actcccgttg
    13681 ctcgaaggga agcaccaagg cgatatttcc ttcgggtgcc aacagtttgc ggctatcacg
    13741 caataaatcc gggagagata gagtatccgt atgccgggct agattacgtt tagtatccgg
    13801 gcatttcaat gaatcaataa aatagggtgg gttggatacg atcaagtcat atttgatatt
    13861 ctcatccggc atatattcgg agagcgaggt ttgatagact tgtatccggt tggcgaaagg
    13921 cgattttgcg atgttttccc gagcttgtaa acatgcgtct aaatctatat cgatagcgtc
    13981 taggatcgcg gtgctacgct gcgccagcat gagggcgatc agtccggttc cggttcccac
    14041 atccaaaatc ctctgacatc tctctgtgct agcccatgcc ccaagcaaaa cgccatccgt
    14101 tccgactttc atggcacatt tatcgtgcca taccgtaaat ttcttgaatt gaaaataagg
    14161 atttgccata tctctatcga ttgtatgccg cgaaattagt aagaattgaa tgaaaagctg
    14221 taactttggc acgtttattg tattaacata tacaatgatg aatgtatata tgaaagaaaa
    14281 gacgagagta ttttgccaga attcgtttga tgacttggat gacaatattg gtatcgtaat
    14341 gccaattctt acagaatgcg atgtagatga ggatttcaca gaaggaatag agaaagttgg
    14401 agacactata cccattcttc cgttaaggaa tatggtactc tttccgggtg ttgccttgcc
    14461 ggtgattatc gggcgtccta aatcgatgcg cctgattaaa gaggctgtac ataaaaagag
    14521 tttgatcgga gttgtttgcc agaaagagat gggtacggaa gatcctatct tagaggattt
    14581 atatacaacc ggggtaatcg ctgacatcgt tcgtgtctta gagatgccgg acggtagtac
    14641 tactgttatt cttcaaggta agaaacgctt tgaattgaat gagttgaccg agacagatcc
    14701 gtatctttcc ggtaagatca ccgtgttgga ggacacgaag ccggacaaga cagaccgcga
    14761 gttcgaggct ttgatctcaa cgatcaagga tttgaccatc aagatgcttg gggccgtggc
    14821 tgaacctccc cgggatttga tcttctcgat caagaataat aagaatgtct tgtatgtggt
    14881 caatttctct tgtagcaata taccgagtgg atcggccgag aaacagcaat tgttattgat
    14941 cggggactta aaagagcgtg cgtatcggtt actttttatc ttgaaccgcg agtatcagct
    15001 ggtggagttg aaagcttcca tccagatgaa gacacatgag gatatcaatc aacaacaaaa
    15061 agaatatttc cttcaacagc aaatcaagac gattcaagag gaattgggcg ggaatatcaa
    15121 tgagttggag ataaaagaat tacgggagaa agccagtcgt aagaaatggc ctgccgaggt
    15181 agcgcaggtc tttgagaagg aattgcgaaa attggaacga ttgcatccgc aatctccgga
    15241 ttattccgta cagacgcaat atgtccagaa tatcgttaac ttgccgtgga acgagtatag
    15301 taaggacaat ttcaacttat ctcatgccca gaaggtctta gatcgtgatc attatggttt
    15361 ggagaaggtg aaagagcgta ttatcgagca tctggcggta ttgaagctga aaggggatat
    15421 gaaatctccg attatctgtt tgtacggtcc tccgggagtc ggcaagactt cattggggcg
    15481 ttccatcgca gaggctttgc gccgcaaata tgtacgtgtt tctttaggtg gattgcacga
    15541 tgaggccgag atccgcggac atcgtcgtac ctatatcggc gctatgtgcg gacgtatcat
    15601 ccagaatata cagaaggcgg gaacatcgaa ccctgtcttt atcttagatg agatcgataa
    15661 gatcacgaat gatttcaagg gggatccggc atccgcttta ttggaggtct tggacccgga
    15721 gcagaataac gcgtttcacg ataattatct ggatatcgat tacgatttaa gcaaggtgat
    15781 gtttatcgct accgctaata atttgaatac gatttcccag ccattgctgg atcgtatgga
    15841 actgatcgag gtgagcggtt atatcatgga ggagaaggta gagatcgcag cgaagcatct
    15901 cgtgcctaag cagatggatg tacatggctt gaagaaaggt tccgtgaaat tccccaagaa
    15961 aaccttacaa gtgatcgttg aagcctatac acgcgagagc ggtgtccgga aattggataa
    16021 gaaaatcgcc aaaatcatgc gtaagctcgc ccgtaaggtc gctagcgacg agcctatccc
    16081 gacgagcatt aagccggagg atttgtatga atatctaggg gcggtcgaat attcccgcga
    16141 taaatatcaa gggaatggtt atgccggcgt ggttacggga ttagcttgga cggctgttgg
    16201 tggtgagatt cttttcgtgg agtcgagctt aagtaaaggt aagggatcaa agcttacttt
    16261 gaccgggaat ctgggggatg tgatgaaaga gtctgccatg ttggcacttg agtatatcca
    16321 tgcgcatgcg gctcagttta atatcaacga ggagttgttc gagaactgga atgtgcatgt
    16381 ccacgtaccg gagggggcga tcccgaaaga cggaccgagt gccggaataa cgatggtgac
    16441 ttctcttgtc tccgccttta ctcagcgtaa ggtgaaaaag aacttggcta tgacaggcga
    16501 gatcacgttg cgtggcaaag tgcttcccgt gggaggtatc aaagagaaga tcttggcggc
    16561 taaacgtgcc gggattaagg aattgattct ttgcaaggag aatgagaagg atatcaatga
    16621 gatcaaaccg gagtatttga aaggcttggt gttccattat gtgagtgata ttcaacaggt
    16681 ggtggatctt gcgttgctga gagaaaaggt ggataatccc ttgttctgat aacgactttt
    16741 taggcatata taggtgtggg cttatacgta tatacgtgta ggcccatatt agtatcggcg
    16801 taagcctata cgtatatacg tgtgggccta cgccgatata ggtgttttta agggaagcgt
    16861 atacttttat ttagagcatt tctgtaagaa ttccaaactg ttgcgtatct cttggatatc
    16921 ggatttgaaa tcatcgtact caatggagat aagcccgttg aaatgctgac gcttcagctc
    16981 gttgacgaac gcttttacgg gtaagatccc ggttccccat gtggcgtctt ccatcttgtc
    17041 ggtgaggtct ttcaaatgcg ccaccttgat gcgtccggat aacttctgga gattcttgag
    17101 cggatcttca cccacccgtt tccaatggcc gatatcggcg catactccca tcaagggaga
    17161 acggcctttc agcgctttct ctaccacctc ggcacttgcg taaatacatg gactcggatg
    17221 gttatggatc gctacctcca tatcgtactt cttggcgagg gattcgatgt agtccaactg
    17281 gtttaactcc ggttcgacag tcacgatatg tgcgcctatt ttatgagcga atgcgaagaa
    17341 cttatcccat tcctcgttag tcccataaga ggctacacca aaggcgatcg gcttgattcc
    17401 ccttttcttg aactcatggc gtaataaagc gcagtcatca tcgctcaagt cgtaatttaa
    17461 atacgtctct tttgggaacg gagcgcccaa ttcttgaaaa aagaaagctt ccgcataccc
    17521 catgcccagt tgctgggtct tatccaaggt ctccatcaac gtaagattgt ggaaagtcca
    17581 agtctgtata cccaccttcc agtccgcttt ttgcgccgcc agctgtacgg cctgcccaag
    17641 gagcatgacc gtacatagtg ctaatataat atatcgtttc atacttatac cggcatttcc
    17701 ggaaggctcc agccttcacg ataggtatgt ctgatatatt cgttggcagc ctctagcgca
    17761 ttgaactccg cgtatttcgt atcgaaatag gggtgaccgt ctatcacctt gaaatcatcg
    17821 ctggttacga tcttcaatac gtcggaagag gatatattgg tgaaacgcat gttttgggcg
    17881 tcccacatca atttcttgtt caagccttgc agacggatcg ctaatacacc caatagcacc
    17941 atctcgttga atggtccgga ataagcgaag ttggaagttc cttccacacg gttctccggc
    18001 gattctttac aagcacggat ccagtcttgc tcatggaaac cgtcaaagta tccggtagcg
    18061 ttcgggatac ggcgcaaata aggggttact tgaggtacac ggccggataa taaccgggag
    18121 ttgaaacctc cgcaatcgca gatcaacgtg tctttagtac ctacgaagat acatccaccc
    18181 aaaccgtcac gcatcatatc tacgccatcc ggtaataagt ccggacgctg aggaagcata
    18241 ccgccatcgt accaatatac tttcacctcc ggtaaggcta cctttggaag attatcacga
    18301 gccgggaagc ggaattctac cacctccgat tgaggagcgg attccgtatt gatctgggta
    18361 gaacggcctt gtacgcgatc cggataacct aacttcaagg attggtaaac cgggtcgagt
    18421 acgtggcaag ccatatctcc gaaagctccg gttccgaaat cccaccatcc acgccagttc
    18481 caaggggtgt agatctcatg gaacggacgc atggcggccg ggccgataaa taagtcccaa
    18541 ttcatcgtct tcggacaacg ttgtttttcg gttgggcgct gtaatccttg cggccagatc
    18601 ggacggttgg tccatgcgtg tacttctttt acttcaccga tctctccgtt ccagatccat
    18661 tcgcataatt gacgtacacc atcgccggag ttcccttggt tacccatctg ggtcgctacc
    18721 ttatatttag cggcgagttt tgtcaataaa cggctctcgt aaacggagtg ggtaagcggc
    18781 ttttggcaat atacgtgctt ccccattgtc aaggccgtgg ccgcaatcgt ggcatgagta
    18841 tggtccggag tagctaccat gacaccgtcg atctggtcgc ccaactcatc gaacatcttt
    18901 cgccagtccc aataacgttt agcgtccggg aattcctcga agcagttctt cgcatatttc
    18961 cagtcgatat cgcaaagccc gatgatgttc tcggttttca tgccgaccaa gttcgggtgg
    19021 cctttaccac cgataccgat accgacaata ttcattgtat cacttggtgc cttatggcct
    19081 aatccagcga tcgttttaga ggggacgatt gttagaccag ctgccgctac ggctgctttt
    19141 ttcagaaaat ctcttcttga ttccatgttg tataatttgt tttttagtag ttactgttag
    19201 aaattgaaac aggaggttac cattctatga tccgaagggt aaggggagac taccacgtcc
    19261 gaggtggcct cgctttcgcc tgtgataaat gagtctgtta ccttacatcc ggaatatagt
    19321 acgaaatcca gacggtctag tatttcttgt tcgctaggaa cgggagtcca tgtatagccg
    19381 ggtgtggaga cctcgtccgg atggattgtc cggtaggagt cgttcatccc gatctcagag
    19441 aaagccttgg ttgccggcca ctccaccttg atcttgtgga tatcggcatc ggcggcccgt
    19501 tgtgtccagt ccaagaaaga aggctcgtta aaatctcctg ttaaaaagac aggataacct
    19561 tctttcatga cttgctgtat atccttttga taacgagtta cttcttcacg ccgggcctcg
    19621 ttggcgaacc ggacagcttc ttcctcggta tcgataaacg gataatcgcc ataaggaatc
    19681 ccattcaatt gataaggttg atacggaata taatatagat ggcaattaaa catccagcag
    19741 aatttgtctt tgcctacttg tatcttcacc ccgtagcggg aagccgtact gtcgacgacc
    19801 ggataacgag ataagatata atgtccctcc ccttggttga aaaggtggaa acctagggat
    19861 tccgcgattt ccggtacatg atcgtgcttg atgccgtctt cttcatagat atgcccttct
    19921 tggattccta cgatatccgt ctggctagcc tcgatcactt tcgctgtctg gctaggggga
    19981 agctttcccc ctagggtatt caaccaaata ttgaaactgc tgacttttac cgttgcctgc
    20041 ttgtcgctac atgcgctcaa tgcacaacaa agtatggcta cgcagcataa aatttcactt
    20101 atcttcctca tgtttctctg gtatttacag gaacaaatat attaaatgtc ccgttctttt
    20161 cactactaag acttcttaat ttattttacc atcggccaag gaaacttcga tacaagctgg
    20221 atgcgttgac ctgtagcttg tgattttcgg gcggcctcga taatctctaa tacgtgtaac
    20281 gcatgctcga catttatacg tggttccgtg tttaatgcca tgtgtttgct gatatcggaa
    20341 gctccttctt gccaaacata gccattggtg tccggaacga aacgctgggg taccggatga
    20401 tccatcgtcg ataagtccac cccgttcggt gcccagtcgt aacctaccat atgcatattg
    20461 ccgtgtgaac cgtataagga gatcgtcgct ttctcctgtc ctttacctaa atgtccgtat
    20521 ggatcgaaat agttgaaacc acactcgata tgagaaagga ctcccttttc gtgttccatg
    20581 ataatcatgg cattatcttc ttctcgaact ttgattttgc ccttatcgtc tacggttctc
    20641 tccggggtta cgattgtagt catggcaaca acggatttag ccggtcccaa taatccggtt
    20701 agggtagcga tgttatagac tcctaagtcg ggcatactgc cacctagcgg ttcgtagaag
    20761 aaagcggacc aagaagggcc ttcatgtccg taatgtccgt gcgcacatgc cagattacct
    20821 agggttcctt tattgatttg ttcggccata aaggcaaatt gaggactgtt tacaacggca
    20881 ggcgcacccc agatacgaag tcccttgctc gtagcgagat cgtataattc tttgccttcc
    20941 ttataggaat tcgccaaagg tttctcgctc cagacatttc ttcccgccat caaagcctta
    21001 cggttcaact ctccgtgaac ctgcatatcg gtcaatgtaa gcatcaagtc gaacttggaa
    21061 ccactaagca tatcatcgat atgcttgtac catttaggta tattatattg cttggccgcc
    21121 ttttgagcac gatccggttt gatatcgcaa caagctacga tttctacata cgggcacttc
    21181 gatatatggg gaaaatattg ggtagataca cttccgcaac cgataacggc tactttcacc
    21241 tttttacctt ccgattcgaa tttctccgca taggcggaaa ggggtgatag tagtgacgcg
    21301 agacttgccg cggccgatac tttaaagaat tcttttctat tcatggcatt gatttcttaa
    21361 tacaattagt ctaaatcctt aatcttcaca ttcttgaaat atactttact tccatggtcc
    21421 tgaaaacaaa gtttaccggt ggtagagata ccgtaatcgg ggaaagcttc ccatttaccg
    21481 ctataacgac gcatcttcca atcttcggac ccttcttgga aagagaatag tttttctccg
    21541 ttcagccagt gctcaacata tccatccttg taaagtacca tagaggagtt ccattctccc
    21601 ggagggttca cctgtttggt ttccggtaca tacatagcgt agttgcaacc cgttttctgc
    21661 cagtcttcta atccctcttt tccggtctcg ctgacccaag gatagttatc gtcatcgatc
    21721 aactggtatt ccgggccggt ttcaaaagga gctttgtatt taggtccttc ttgtacgtga
    21781 tataagaatc cggagtttcc ttgcgctccg attttccagt cccatttgat ctggaaatta
    21841 tggtaattct taacggtaac gatatcggta cttaccttga tcgtagtatc cgctatcacg
    21901 tcaccaccgt ttccgtagcc gacgatcacc ccgtcttcta cctgccatcc cttgacatca
    21961 cccccgttga acattttcca accggtaaaa tccttgccat tgaataacaa ggtatagcct
    22021 tccgcttttt cttcctcagt caatacatta tcttttactt ccgtggatga ggaacgactt
    22081 ccacatgcaa ccatacacat cccgtaaatg gttactagaa aaatagatac gatctttttc
    22141 atatattaga atatttagtt taattatctc cttatgataa cgccatttga tatggtttat
    22201 ttgttcattg gcaaaaatac tgcacataaa ggatttggat aatagagtat ctagctaaaa
    22261 aaaatggatt atctttgcgt tattcagtaa ccatctaaaa gttctggttt atggcgaaaa
    22321 taaagcatgg tttttccggt cagcgattga ttgtctatcc tttctacgtt atagaacaag
    22381 cgttgaacaa cccgttagtt gcggacttgg tcgtacactc tatggggtat tttccgaagg
    22441 cggaaagcca ttatattgat cgtgcgtccg gttgtggaga gtatctttta atttattgca
    22501 ccaaaggaga gggctggtac gtgttggatg gaaaacgata tgtcgtaccc gagaatcatt
    22561 ttttcatcct cccggcagag aagccccatc aatatggttc gagcgagcat gatccttggt
    22621 atatttattg ggcacatttt aaagggaaaa aggcgaagta tatcagcgat caactgcaag
    22681 gggtgatccc gatcgacatg gatgataatt cccgtatcgg cgatcgtatc gccttcttcg
    22741 atgaactatt gaatgtgttg gagagtggga cggatgaggc tacggttaat tacgtcaatt
    22801 taagtttcaa tcatttgatc gcctctttcc tctatgtgaa gacgtatagg gaggctaaat
    22861 tctccaaaag caaggcggag aatacgttct ttattagttt ggcgacccac ttcatgacgg
    22921 agaatctgga gaataaattg acattaaagg aattggcctc tcatttcggc tattcggaat
    22981 cttatatgta caggcttttc ttcaaggaaa ccggttatgc tccgatgaat tatttcttgc
    23041 atatgaaaat agaccgggct tgccagctat tattacatac gaatatgaag atcaatcaag
    23101 tcgccttgaa actgggcttt gacgatccct actatttcag ccgtatcttt aagaagatag
    23161 taggtacatc gcccaaggat taccggcact cgttgccgaa gtgagatatt tacgatgaac
    23221 ctaaacggga gcttagggct ggcggtattt attccggtcg gcttccgtta tttcccggat
    23281 tacacggcag ggattgccgg cggctatgac attggccgga atatctttgg ttacgacgct
    23341 tcctccggcg attaccgtgt tatcgccaat ggtcaccccg ggaaggatac aggcttgcgc
    23401 cccgatccat acgttatcgc cgatagtcac gggaaaagcg tattccagac cttcattacg
    23461 ttgctttacg tcaaaagggt ggccggcggt atagatgcct acgttcgggg cgatgaacgc
    23521 gttattgccg atacgaactt tcgctccatc caannnnnnn nnnnnnnnnn nnnnnnnnnn
    23581 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    23641 nnnnnnnnnn nnntcattac gttgctttac gtcaaaaggg tggccggcgg tatagatgcc
    23701 tacgttcggg gcgatgaacg cgttattgcc gatacgaact ttcgctccat ccaagataac
    23761 gagattcacg ttggcgaaga aattatcccc aatctcgata ttatagccat aatcgcattg
    23821 gaaaggggat aggataacgg tgttcttccc tttcttgcct agaaaagagg ttagaatccg
    23881 atctttttct tcctcttggt cgggaggcaa ttggttgtat ttgaaaagga cgcatttcgc
    23941 tcttttcatc tcatcttgaa gctcactatc atgattcgcg ttgtataata gaccttccgc
    24001 cgctttctct ttttctgttt tcatatgtct cttactaaga tttataaaac gatgatttgc
    24061 gcgaagatac tattttattg ggaggagttt atcctccgat tcgtatttcc aaacccattt
    24121 tttcccccat ctccttaaag gggaacagct cttctttggc tagcatttgc tcgcagggat
    24181 aaggataggt gagacctaat tgctcgtatt tatctttgcc caatgtatgg tagggaagca
    24241 ggtgtacgca tttgatacga ttttctttcg ccagcatgaa tatttcccga agcgtattct
    24301 cattgaaatt gaaaccgggg attaccggta cacggatcgt tactttatta gcgctcttac
    24361 tggatatata ccgtaaattc gtgaggatcg tatccaagtt cgctccggtt tctttctgaa
    24421 gtaaatcctt gtccgtatgt ttgatatcga acaagaacaa atcgataagc ggaagcgctt
    24481 gctttatctt atcaagattc acttgcccgc aagtctccac ggaggtatgc agtttctcgt
    24541 tcttgcattg gatcagcaaa tccatcaatc cctcgaattg cgtgaaagct tcgccaccgg
    24601 aaaacgtaac ccctccaccg gaattcaggt aataatcccg gtcacgtaaa aggatttcca
    24661 tgatctcgga tgaggtaata gattcaccga caaacttaat ggcgttctgc gggcatatac
    24721 gctcgcaagc cttgcaggct acacaggcct gacgattaaa caccggaaaa tggtcttgga
    24781 tggcgatatt gccccgtgga caaatcgcct cgcaacgtcc gcatccgata catttattct
    24841 tgacatggag cagatgcggt ttccttttct gggattccgg attggagcac catggacaat
    24901 gtaaaggaca cccttgaagg aaaacgacgg tccggatgcc cgggccgtcg tgaacggcga
    24961 accgttcgat ctccatgatt gataacctat tctcgctaac cttatattta tttatcatac
    25021 aataccctgc ttaaaagttc ctgttgaata ttgggagata aatcgacgaa taccgcggag
    25081 aacccgctta cccggacgat taggtccggg taattttccg ggtgctctac cgcgtcttct
    25141 aaaactccct tatctactac agtcaccatc aagtggcaac cccctttcgc aaaataagtc
    25201 ttgaacaggc tcttgatgac agccctgttc tcgttgaaca tggaaggaga aaacttaatg
    25261 ttttgtaccg agcctccatg atacttggcg tcgaacttcg ccaaggaatt cagcatggcc
    25321 gtggggccgc ttttattcgc tcccccttgc ggattattgg caggattcat atacatgcac
    25381 gataatcgtc cgtcgggtga ggcggcggtc cggtttcccc attccgtgtt taattgatta
    25441 ttgctgataa cgatcaagaa gtattgcata ccgatggcga taccgcgatt gcgtacgcct
    25501 ttcgctacga actcgtacaa atcgttggcc atcgtatcgg cagtctcaag gtcgttacca
    25561 tatttatcac agttcaggca atcttttcgt aaagcctcat agccgttgaa attagctagc
    25621 atggcatcat tcaattgccg taacgtgtat tttttttgat tgaataccag atcccggatt
    25681 acccacaggg aatcggaagt gttgatattg ccatacgtct cgtttgtccc gcctagataa
    25741 cgtacgcctc cgtccaaaag cgcttttccc cgtgcgatgc aatcatcggt caataggctg
    25801 gtaaacaaga aacttacgtg ctggttcatc acctcatacg aatggtattg ggctttgaca
    25861 gacagatcca gataataatc gagtaaagcc ttgtaaccgt catagaattc ctcgaatgtc
    25921 tgatactcct ctaatttctt tagagatacc ggcccggatt tacgtttacc gtcaatcggg
    25981 tcgataccat cattcatata aatcgtaagt agttttagta aattgatgca aatgttgggc
    26041 gtacccgtac tctgtccttg tatcacgaac tcggtacaac cgaaaggcac gtattgttcc
    26101 gccgttttct cgtctacacg cattccgtac atgacggccg ggacgtttac atcatcattg
    26161 taaagggtcg ggtaagtagc tcccgcaccc aaagcgtcca acgcttcgtc ccagatttcc
    26221 tcggaggtct ctttatcgaa gcgcaaggtg aattgtggct ctacatatct gcaatttttc
    26281 gctactttca tggcgatatg caggaatacg tcggcctctt tcgggtgttt gcgcccttta
    26341 ccgcctacga tgatacgtcc gtttacggtg gtacggcgat tctcaatcat ggtccaaagc
    26401 gagtggatat atcggtatgc ctcttcgtcg gtcaatcgcc cggacttgag atcggctact
    26461 aaataagggc ctagataatc atccagacga ccgtagttta taacaccggc caacaaagcg
    26521 aataaccaga ataactgcat tgcttcatgg aacgtaccgg gtttcttctc cttgatgttc
    26581 tctagggctt ggcagatacg ctctaattct ttttgccttt tcatgttggc tgaagccatt
    26641 tgctctctag cgtcttgctg gagatgagaa gcacaatcta caaaaatatc cagacattgg
    26701 atgcctgctt tgtaaaagtt attatcgggt tgctctttga gtttctccag taaatcagag
    26761 cgaaggccac cgatgccctt atccaatagt ttcgggtaat ccagcatcat tccagataga
    26821 cgtgcggtag cgatcatcgg gtattcgcag tcgatgaaca tacccaatgt atcctcggtg
    26881 aggacctcct tgttgaattg ggtctttaaa tcgtgatcca accaataatc atataacgca
    26941 tccacccgtt ttcgttcagt ttcatccagt tgtagctgga aggcacggag tttcttgaat
    27001 acgcaataat gcccgacacc ccctaatgag gttacgcatc cgaacccgat cggtaggaag
    27061 tccgtacgtc cggcgatcaa gtcttgattc gtgatcttgc gaaatagcgt ggggtataaa
    27121 actttcaggc attccacttc acgtatctct ttgggtaggg cggcacaggc tttatggact
    27181 gccgtatacc gctccatgat ctccagttgt acgatcagag gtttctcgca aggtattttc
    27241 ttgctgatct ctacgttttg cgccccttct acattgaaat ttgccatatg attattgttg
    27301 ttaatattgt gtagagacgg ggcatgccct atctctacaa gcagatgatt ttttaatgtt
    27361 tgcttctttc ggcttcccgc cagttatttt ggtaaccggt tagtaagtcc gtaaaacgtt
    27421 tcgtgatcaa gtgcggacgg gtgatcgcgc tgcctactac tacggaatga gctccgagga
    27481 agatacattt catggcatct tccggcgagt agatatgccc ctccataatg acataggctt
    27541 tgtctttaaa gtcacggcac atacgggcga attcccgtaa atccggttgc tcgatatgct
    27601 tggttgcttc cgtatatcca tacaaggtag ggccaacgat atcggctcct atttctacgg
    27661 cacgtacagc ttcctcataa ttagagacat ccgcaaaaat gatagcttcc ggtatctctt
    27721 tcttgacgat tggtagtaat tcgtatgcag ggcggccttc atgggttatt tggctcgtac
    27781 agtccaaggc gataatctcg gctccggctt cccatacggc tttagcggcc tctaaggttg
    27841 gggtgataaa cacatccgtg tcatcgtgcc agattttcca aagcccgatt actggtaaat
    27901 ccacttcttt tttaatcgcc ttgatctgct ctgggtcgtt tgcacggata cccacggctc
    27961 ctccccattg ggcggctttt gccattttta cgacaaagtc tactgaaaaa gtcggatcat
    28021 cgtgttgtac ttgacaggat acgatcagtc ctcccttgaa tgaatctaaa agttctttct
    28081 tatttgtttt catatttttt tcgttacatc gttttctcta aaagcgcggc gccgattatt
    28141 ccggcgtcat ttcctaattc cgcacggatg acttggggga tacctatttc ctcggcggcg
    28201 aaggtacaag tatgtagttt ctcgtttaaa ggtttcaaca gcaggtcacc tgcatgtgcg
    28261 ataccacccc ctaagatgat tacttgcgga cggaagatgg ttatgaacgt ggagattccg
    28321 gcggccagtt tactgatata gtcatcgacg atctgtttag cgagggaatc cccttgttta
    28381 gcggcctcga aaaggatttc tccattgact ttattttcgt cttcgccgca aagtttccat
    28441 atcaaggtgt ccttattctc ttgtaaggcc tctttcatga tgcggattaa tgcggtagat
    28501 gagcaataag cttccaaaca gcctttttgc ccgcatgtgc aacgttcgcc attgtatacc
    28561 aatttggtat gtccaagctc tgctcccata ttatcggctc cggaataaat cctcttaccc
    28621 atgataattc cgcctccgac tcctgttcct agcgttaaca tgatggcatc ggtatattgg
    28681 ctggccgatc cggccaagac ctctccatag gtcgcgcaat tggcgtcgtt ggctatataa
    28741 gtaggcaatg aaatatgctt ctttaaatag tcgtagatgg ggacattctt ccatccgaaa
    28801 caattggcat gtaccaaaag gttcgtcttt ggatttacgt aactgggcat gccgatgccc
    28861 caagaagaga tgtcttccat ttgcaagcct gctttgagaa ccgctttttt gctgacttcc
    28921 gccatgtcgg cggtgatctc ctcgatcgtg cgtccggctt gtgtcggtat actctccttt
    28981 gcgataatct ggtgattctc atctactacg ccagcgacca tattggtacc gccaacgtcc
    29041 agaccgagat aatacttggt gctttccatc tttgctcttt attttatgag gtcaatagag
    29101 tgaattattt gttggcaaag atagaggagt tacccgccct agacaatgtg aggtttagcc
    29161 taaaataatg gactattttt gcataagtgc tctcgcaagc ttacgagagt actttagaga
    29221 agaggtgtta tcgagaggag acttctgtaa taaccttcaa atatagtgtg actgtgtttc
    29281 tttatgttta aagaatcata tcgtaggtcg attctattat ttttctcgat gatggagcaa
    29341 gcctctttta tcatgggctt gaagtcttct tctgttttat ctttgtctcc gttggctagg
    29401 tagatatata attttttttc tccttgatag gtttccgtga acactcgtaa cctatcaatc
    29461 atcatatttt cgctgtattt atagttcggt gatatggcta taatataagg aaataagtct
    29521 gggtgttcca tcatcgcata agtgacgaat gtccctccca acgaatgtcc gactaaaatc
    29581 ctgttatttc ccgcatggta tttttcttgg atgaaaggga ttatttcatt cgttaatgac
    29641 gagagcattt cttttccatg tcccgggttg tcatatcttt ttaccgataa ggaatctgtg
    29701 aaaggcgggg tcagctcact ttgcctgttt gaattaaata ttccaacaat aatacagggt
    29761 atgttgggat gtgtcaactc gaatgttgaa caaaataaat tgaatgtggg gggatattgt
    29821 gcgtctaaga cataaatagc gagtaaagag tctcttttaa ggctaccatc tactccgctt
    29881 aaatagactt gcatttcacg ggtctcttca aaatagtctg agttgtagat atatcgactc
    29941 cctaatgcct gcatcaagta gaaatcggct tgcgcatgta tccggcatat tcctgagaat
    30001 aatacgataa gaaagagaag aactgttttt gttttcataa atagtgatat ctagaattat
    30061 gcaaatatag cgaaaaataa agtctttaag tatgtttaaa aaaaggaccg gacgatgggt
    30121 atcgaacggt cctttcttta atctttatgt cgtatgctgt tattcagctt ctttttcagc
    30181 agcttccttt tctgccggag catcttccgg ggtaaagtca gtgatgcctg cgttgatcaa
    30241 gatgttatac caagagagta gtttcttgat gtcgcttgga taaacacgct cacgatcata
    30301 gctaggcaat acctcggcaa agtacgcacg caattggtct gtcgtggctt tggaaggtac
    30361 caaagaagcg gtttttccct cttctttatt ctttacgcta gtcaatacct catgcaaagg
    30421 cacttccgtt tcatccgtat agattgcgat atcgcctaat gagattactt tatcttttgc
    30481 gtatgcgggt actctcttgt tatcagtcag cgattcaacg atcaacatgt tttttccatg
    30541 ggaaaccagt ttatacagac cgggttttcc cgaaatagac aaaatagtct tcaacataat
    30601 gttttttatt ttctattagt gttaaacttc gaggtgacaa aggtaataag aaaaagtgga
    30661 attcttccgt catgaggaca gttaacttcg ttggagaagt atcttaggtg cattgacgaa
    30721 gtatcttagg ttcgtcgacg aagtatctta agttcattgg atgatgaagg taagatactg
    30781 taaaagccac tcgtcccgct atcggtgatt attgggattg aagccaacat aacagtttgc
    30841 ctacttgcgg tataagggcc tgtctgttgt cattatagat aacgtaatcg gagcgatctt
    30901 tcttttcctc gtccgacatt tggctgttga ttctgcgttc gatttcttct ctcgaggctg
    30961 agtccctccc caaggctctt tcgatgcgga gttctcttgg ggcatagacc atcaagctta
    31021 tgtctaccac tttgtagaaa ccggattcga ataatatggc ggattcgatg gcgcataaag
    31081 gggaagtctg tctctctacc caagccgaga aatgacggtt tacctcagga tgaatgatct
    31141 ggttgacctg ttgtaattgt tccggattat taaagatgtg ggaggctaga agtttcttgt
    31201 tcaatccctc attcgtataa atctccagac cgaaaagggc tgttaatttc tcacggataa
    31261 ccggggagtt atttgtcagc catttacttt cctcgtccgc tatgtatacg ggtataccgg
    31321 ataacgctaa taaagaggct acgacggatt taccgctccc gatccctcct gtaataccta
    31381 ttttaatcat gcttattgtt gtgttccaaa ataaattcta ccttatctgg caataaggtt
    31441 gccgtatgta cccagtctgg tttcttggtg agtttgacgg gtagggtacc agatacgttt
    31501 tgctccagat cctcaaaagg tatatgaatc gagaacatat cttccgaaag tcctttgaat
    31561 cgggacaagg gcacactgca agtcactttt acgaccgccg gaaacatacg taccgtataa
    31621 tgtggcggta tatgactgca agagacaggt atttccaacg tcttctccgt gtactcctct
    31681 atcggaatcg tgatagatac gttttccgga tcgaagttaa cgccgtctac tttgattagt
    31741 tgtacggttc tcgtaatgtt tttattcgct tttttaactt cagtgaaagc cgtcttgacc
    31801 gaggtcaacg tatctaagat cgctgcggtg gcataagcgt tgatcttttg gggattgatt
    31861 tggatatccc cggataattg aaagccggct tccatatgaa tatcaccatt aaaaacgacc
    31921 agtatttcct tatggacccg ctgactgaaa tccatatcta tttgttgcgg atcaaaactt
    31981 tgtaatgccg tagtggctat caattgtttt tgaatatcgt tctcgatctg ccttttactt
    32041 acttgaaccg aaccattttt ctccttcgta ttcttcatgt tcacttcaat cggagcaaac
    32101 gatcttccaa aagtatagtt gagtaaaacg ctacccttgt cttttacctt tgcggtaatc
    32161 gtttccacct caggggcatt aaacgctata tcggcaggta cgttcttata cttaaccgga
    32221 aaaacaagtt ctatctcata ttcctgctgc aagctttgga gtagccagaa accgaaagcc
    32281 aaaagggcga aaaagaaaaa gaccaagacc tctttccatc tgtctccgtg gaaaaaagcc
    32341 ttagtctttg cttggataga cttgaaggaa ttttgtatgt tctcaagtcg tgacatattc
    32401 tgtagttaga ttatttctgc tgctgagcgt cttccgctga agcgaaaata gaagttttat
    32461 ctacacggat acgtactcca tccgctacct cgattagcat ataagtatca ccgatctctt
    32521 tgatctttcc atagatacct ccggcggtaa tcactttatc gcctgttttc aacgcctcac
    32581 gtgatttctg gatttctttt tgtttctttt gttgcggacg gatcatgaag aaatagaaga
    32641 tagctacgat aactaccatc atcaaaatac cggaccactg acttcctcca gctggagttt
    32701 gaagtaaaat actgagtaag ttcatactat aataatcgtt ttacaagtta atatcaataa
    32761 tgatatgcac aaatgtaatg ataataatta atctttgagc aataacttct ctttttttaa
    32821 ttcgttgact attgaatcca gaattccgtt aatgaatgtt ccgcttttag gtgtactata
    32881 atactttgcg gcatcgatat attcatttaa ggtaacgttg atgggaatgg tcgggaacga
    32941 taaaatctcg gctaaggcga cttgcatgat gatcaagtcc atattggcga tacgttcggt
    33001 ttcccaattc ttcatatgtt tgtcgatgcg ttcacgatat tccttacctt tcaacaaact
    33061 ttgacggaat aacttgattg cgaaagcctt gtcttccaaa tccttgaaca ttggcaataa
    33121 ggcttgtttg ctacctttct tctcctcgaa tttcttgata gtcttcaagg cgaaagtctc
    33181 tacgatctcg atatcgtcat tccagtagat gcttttatct tccagatatt cctctatcat
    33241 ctcgtttcca cagattattt tcttgaagat ctggcgccag aactcacgat ccgtctcgta
    33301 cgagtcttct tcgtttttca agtattcggc gtaaatctca gaacttagga tcgtatccaa
    33361 tacgttctta atgaactcct cgtcgttgct ccatgagaga ccttgctcgt ctacatactt
    33421 tttcaacgta tcgttttccg ctaattgagc gacgaaacga ttgtctatga agcgtgtatt
    33481 cgggtttaac tcctcgtcgg taggcatgta tttgcacttc cgggtgtcaa ggatccttct
    33541 ttgcaggttg gtaacttcga taattaggag taagaaataa taatataagt catatgactt
    33601 ctgaaggctg aaaagcaatt cgttttccgc aactttgagg tcaccgtttc cgttttgata
    33661 gtaagagtat actatctgta aaactttaat gcggattaaa attctgttga tcatcgtttg
    33721 aaggaacttc ttattataaa ttaggctgca aaggtagttg ttttttccat aaaagaatcc
    33781 ggatttactt aattttatat gtgttagatg atattttaca aatttagcct caatgggcgt
    33841 attttcgatc gttaaaatag ttgctaatta aaaaaaaatg cacatatttg aagcaagttc
    33901 tataaagtgg gtgggttttt aacgaatgtt agctgtcatg gaagaatcaa ggaataaaaa
    33961 acatgttgaa ggtggcgaca gggagattct atactctaaa gccattaaag cgggaaaacg
    34021 gatttattat ctggatgtga agaggaattt gaaagatgac ctattcgttg ccgttacgga
    34081 aagtaagaaa attcaatcaa aggatggttt gcaaatctca tttgagaagc ataagatttt
    34141 cctttataag gaggactttg agaagttcat ggagggaatg caagatgtaa tcagttatat
    34201 caagaactca aatctgaaga aatctgcgga agacgtggtg gaacctgaag aggaggaaac
    34261 gattcatggc gattccccag aggaggatat ggcttccggt gatataaagt tggatattga
    34321 gttttaatat aacacgaaga gaaaaagata acgggctgtt ttactcatag agagaaacag
    34381 cccgttatgt gttaggagct ttccgcaaag gaaaatccta ttctttgctg cgaattattc
    34441 agccgggtgg atagcctctg taggacatgc gtcagcgcaa gttccacaat ctgtacacat
    34501 ttcagggttg atgctgtatt tatcaccttc tgaaattgct cctaccggac actcatcaat
    34561 acaagttccg catgcaatac aatcatcgct aattacgtaa gccatttttt aaacgtttaa
    34621 attgataact attagtaggt gcaaaaatat agctttcttt ctatttaaaa aatatctact
    34681 ggcttatttt cttcaaaaat cttctttttt gcaatatctt tgtcgggttt tcgttattaa
    34741 acaaaatagg ttgagatttg agacgattat tacttatatt atatgtggta agcttggcta
    34801 ccatgggagc catggctcaa aaggaaaggg tgaggaatca gccgtacgct gatttgaaat
    34861 ggcttcatct ggggtttcat gtgggtattc actcgcagga tttgttattg acccataccg
    34921 gtgtcatgac caatggagag acttggttcg cggagattcc ttcttactca cccggcttta
    34981 gtgtcggggt gatcggagat atgtatatga atccttattt caatttacgt ttcacgcctt
    35041 ctatccattt cggagataag aaatttaagt ttcgggaaca ggctacggga gaggaattca
    35101 tcacgaacgt tcgttccagt tatctgaatt tccccttaga cgttaaatat acggctttac
    35161 gcttgaataa ttatcgtcct tatttgatcg gcggtatcta tggctccgtg gatataggcc
    35221 gtaagaaagg taatccgatt ctattgaaaa gcacggactt cggatttgag tttggcttgg
    35281 gatgtgatat ctatctaccc tactttaagt tatgcccgga gctgaaattc tgtttcggat
    35341 tggttaacct attggagaaa gatcgtccgg acttggtaga tcaagcaaat atcaaatata
    35401 cggatgcctt atcgaaagct acatcccgta tggtgatcct gacatttaat ttcgaataaa
    35461 taactcgata tagatataag cggccggtat agccatcatt acgctatcga agcgatccag
    35521 catgcctcca tgtccgggta atacatgccc ggaatctttc acgcctaacg tacgtttcat
    35581 caaagattcg atcaagtcgc cccaagtccc gaatactacg atcgtgccgg ctaatccaag
    35641 ccatgtgtac cagttcgtgg ccggcatgaa ccaagcgaat atttgggagg ttattaatac
    35701 gaatgccaac cctccgtaaa aaccttccca ggacttcttg ggagagatac gttcgaacaa
    35761 tcttcttttt ccaagcatag atcccactag ataagctccc gtatcattta cccatacgaa
    35821 aacgaaaata gccaaggcaa aataggggat atgtacgatc tcgcccggcg tattaggtac
    35881 cgatgtaata aagtttagca gagagaaaga gcctgcgcaa tagatttgac cgaataaggt
    35941 caatgcccag ttattgattg gattactggc tttatcgtaa agctcggtga tcatggtata
    36001 cattaagaat aaaagatagg ggagaaatat attgcctcca accaagccat tggcgtaacc
    36061 gaatgtggcg gcgaagaggt aggctccccc caaggaactg acaaatcgtt tgatggcggc
    36121 attctcataa tgtttgacca atccgtagaa ctcccataga gaaagtccgg taatgagtcc
    36181 aaataccgta agaaaataat aggagtggaa atagatcgca ccgaccaata ctgcgacgaa
    36241 aataatgcca gtcaatgcac gtgtaatcag atttttcaaa acaatagtgt ttttgcttgt
    36301 ttgtaatttt ggctgcaaat ataactaata aattgataat acagcaataa ggaaggctgg
    36361 atagtaactt ttgatcaaag atacgcccca gccttacttg ttatgaatgt cttgactttg
    36421 gtcaagctat tttccctgtc ttgttttctt cggtaggagt atcggttacg ttttccattg
    36481 ttgcgtccgc tttcgcctcc ttatccgcat tctccttgtt ctttccgtta gccttttcct
    36541 gcaactccag aatctcttgg gaacgggaga tccaggctcg tttcccgaag atatgctcta
    36601 catcttccga gtagattacc tcacgatcca ataatacctg cgcaagttta ctatgtcctt
    36661 ccttattctc ggataatatc cgttttgccc tgtcgtattg ctcattgatg atcttctgta
    36721 cttccgtatc gatcaatttt gcggtctcct cactataagg cttggtgaat ccccaatcct
    36781 gtccggtgga gtcgtaatag ttcaagtttg gaagtttatc gctcataccg aagtaaacga
    36841 ccatcgcata tgcttgtttc gtgacacgtt ccaaatcgtt ggatgcgcct gtggatattt
    36901 ttcccaagac taattcctct gcggcacgtc ctcctaaagt agcgcacatc tcgtcctgca
    36961 attgctcgcg ggtggtgatc tgtctctctt ccggcaagta ccatgccgca cctaatgcct
    37021 taccacgggg aacgattgtc accttaacca gcggattggc atgttccaac aaccaactta
    37081 acgtagcgtg accggcctca tggttcgcga tacatttacg ttcttcctcc gtcgtgatct
    37141 tcgaacgttt ttcaagacca ccgacaatgc ggtctaccgc attcatgaag tcttctttct
    37201 gtacgaattt ctttccgtta cgggcggcga tcaaagcagc ctcattacaa acattagcga
    37261 tatcagcacc cgagaagccc ggagtctgcc ttgctaggaa ctcagcatct acgctttcat
    37321 ctatcttgat cggacgcaaa tgcaccccga atatctcttt acgttcattc aaatccggta
    37381 attcaacatg gatttgtcgg tcaaaacgtc cggcacgcaa caacgcttta tccaaaatgt
    37441 ccgcacggtt tgtagcggct aagataataa caccactgtt agagccgaaa ccatccattt
    37501 cggtcaataa ctggttcaac gtgttctcac gctcatcgtt gctattcata ttcgcgtttt
    37561 tcccacgggc acgacctacc gcatcgatct catcaataaa gacgatgcaa ggagattttt
    37621 ccttcgcttg gcggaataag tcacgcacac gggaggcgcc tacaccgaca aacatctcca
    37681 cgaaatcaga accagacaag gagaaaaacg gcacattagc ctctccggca acagccttcg
    37741 ccaataatgt cttaccggtt cccggagggc ctaccaataa tgcacctttg ggtatcttac
    37801 ctcctaattc ggtatatttt tccggattct ttaagaaaga gacgatttcc tctacctctt
    37861 gtttcgcttc cgccaatccg gcgacatcct tgaatgtcac cttacggtca ttatctttat
    37921 caaaaagctg agcttttgcc ttcccaacgc tgaacacgcc acccggacct gcgccggtac
    37981 caccggacat acgtctcatc aagaacatcc atacaccgat caataagata atcgggccga
    38041 atgaaaccaa gaaattccag atagcgtcat cgccttcctc gaaccggact tgtgtatcga
    38101 tatgactatc ggctaccgct ttgtcataga aatcggaaaa cttgtcggcc gacgggatct
    38161 ttacgtatac tttcggagaa accccgattt tagaaacgtc catattccca aagacctgtt
    38221 cagtctttcc atttttcact gtagcctcca ccaagttctt cttgttgtag actgtcattt
    38281 tatcgaatac gttttcctgc gctagtttct ggaactctgt ccagcctagc tctttcgttc
    38341 ccgaagaatc atttgtcatg tatagggcaa caagcatgat gaagatcaac ccgtacatcc
    38401 aatacaaatt aaagcggaac atcttaggtt tcccgctctt cggtgtttta ttaaacatgt
    38461 cgtttttatt ttccataaga gattatcatc aaatatttag accggcttaa tcaatgttag
    38521 gtacttgtat aaccttcgag tctgcccaaa ggttctccaa gttataaaat gcacgttgtt
    38581 ccggcaagaa tatatgtaca agaaccgtgc cataatccat gccgatccat tgagcgccct
    38641 gtgtaccgtc aatagacaaa ggcttctcat ttgcattctt gcgtgcgaaa tcccatacgg
    38701 aatcggataa agcagaaact tgggtaggag tgtttccctc acaaataacc atatattgac
    38761 aaatggcacc agaagtctgg cttaaatcta ctgttacaat atttttgcct cttttttctt
    38821 gaaggccttc aacaatcgtt tttactaatt cttttgtttg atccatttat ttctattgat
    38881 ataattttcc aagtcgcaaa tatacttctt aattcgttac atacgtcttt ttctttcatt
    38941 aatatatgtg taatagcttg tttgagacta tctcctcgat cgttataagc ttttaaaaaa
    39001 acacgtacgt ctttttgaga aaacatgtac gtgttttatc cgaaagacgt acgtgttttt
    39061 tctggacatt tttttcgaaa gtttgtttgc aaattttgaa aaagtatata cctttgcatc
    39121 cgctaacaag agagttggtg atttgttaaa tattgttcta tggtgtaatg gtagcacaac
    39181 agattctggt cctgtttgtc ctggttcgaa tccaggtaga acaacgttta aagtttactt
    39241 gacaattttg tagagattgt tctatggtgt aatggtagca caacagattc tggtcctgtt
    39301 tgtcctggtt cgaatccagg tagaacaaca taaaaaagcc tcgttattcg ataagagtag
    39361 cgaggctttt ttgttgtaga tatcatgtta ttatttgtaa cgaagccatt tggacatctc
    39421 ctttatactg ggtttcttac catacatgag aatgcctaca cggtatattt tggcggaaaa
    39481 ccaagtgaaa ccgatggatg atatatacaa aaatccaatg gaaagtagta tttcccacaa
    39541 aggcacctcg aatggcaccc ggaccatcat cacgatcgga gaggtgaagg ggatcatgga
    39601 gcaccagaaa gctaatggtc cgtcagggtt ttccatgcta tagattcccg catagagggc
    39661 gaaaactaaa aggagcgtga ctggtagcat gaattgttgc gtgtcttctt ggccgtctac
    39721 agctgatccg atagcggcga ataaagaaga atataataag tagccgccta tgaaataagc
    39781 gataaacaag atgcctatct cggtgaagtt aatcgtatga agcatctcta tccattcatt
    39841 tccatgctgc tgggctgcga tagccgtcat gttaggggtt gtgttaagtg ccatgcttga
    39901 ttgcaagatc tcgctttcca tacctcctcc caaaaagaaa gttcccccgg tgatgagaat
    39961 aaaggtcata accacccaaa ggaatacttg cgtaagcccg acaaaaccga ttcctataat
    40021 tttacccatc attaagtcga aaggtttgac ggacgagatc ataatctcga tgattcggtt
    40081 cgtcttttct tccataaccc cttgcatgac cattcctcca tagattagga tgaacatata
    40141 gataagcatg gtgaaaatta ctccggttat ggatgccact acggacgagg attgcttttc
    40201 gcttccgtca tccccccatt tgatcgtttg tatgttgaaa tctactttac tttcttttat
    40261 gatctcttgt agattgggga tattgaatgt tgccagtttg tcactctcta tctgcttctt
    40321 taatgtcata ttgacgagtc ggctcaaatc cgccgggatt tgtttcttgg aatagagggt
    40381 tgcgtttttc ggatttttct gcaagtcgtc ggagatgttg agaaatgcga atatctcctt
    40441 ttccgacatt tgcctgtact tatccatatc tttgtcgccg ttgataaaac gatagctttc
    40501 cgtatcctcg aacaacgggg cgtatttgcc ggtggcgtcg agtatggcga ctgtatgaac
    40561 ctcatctccc ttgatggaag agagccatag ggggacgaac gcaagtgcag cgaatagaaa
    40621 cggtgtgagg aacgtgagca ggataaatga ctttttactt actctccgga gatattcccg
    40681 tttgatgatt aatccaattt tgctcatacc tttgatgtgt ttgtgccgga aacggtgttg
    40741 ataaaaatgt cattcataga agggatctcc tccgtgaagg aaagaatctc atattgggac
    40801 gccagccggg taagccaatc ggagttactg atattttctt ccttgcgtat ccttaactcc
    40861 tcaatacctc cagtctcctt gcgtacattt aatatatagg tattactctt aaaccgttcc
    40921 cgtacctcct tgacatttcc ggacaggacg acctcagagc gattgattaa agcaatctcg
    40981 tcacaaatct cctcaacgga ggacatgttg tgagttgaga atataatggt atgtccggcc
    41041 gccttcaact ccaatatctc ttgtttaaga cgatcggcgt tgaccggatc gaatccgcta
    41101 aatggctcgt caaagatcaa tagctcgggt tcgtgtatca cggtaatgat gaactgtact
    41161 ttctgctgca tacctttcga cagctcttcc agtttgcgat tccaccaagg catgatgtca
    41221 aatttctcga accagcgggt caaacgactg cgtgcctctg ggtaggagag acctttcaat
    41281 tgtgccagat agatcgcctg ctccccgact ttcatctttt tatacaaccc tctctcttcc
    41341 ggcaagtaac cgatctggta gatgtcttcc gggctggatt catggccgtt gaagcgaacg
    41401 attccgctat ccggtgccgt aatccggttg atgatccgga tcaaggtcgt cttgcccgcc
    41461 ccgttaggcc ccagtaatcc aaagattgtt ccttgaggaa cttggatact taccttgttc
    41521 agcgccagat gcccggcgta ctgttttacc acgttttctg tctcaaggaa attcatagat
    41581 gtttttttat tacattttta atacgatacg ctcacccagc tctttgcaga gcacgttctt
    41641 gatctcgttg aggtgggcgt tctgtttcat taaatcaaag atcagctcca tgtctccctt
    41701 gttttgagcc tctttgattt tcgcttggat atcctttatc ttatagagga tataggcatc
    41761 tttcatggaa tagatttccc ggggtaccaa gtaatccaat ttatcttctt cttgctccag
    41821 ttccctgaac ttcgtatgat atttactaag ctggtactta tcgctgataa ggttggcggc
    41881 aagccggctg atgttcgggt ccggatgggc aaggaaataa cgactggcca taaagccctc
    41941 gttttgacaa tgttcagcag cttcgtccag catttgtttg aaggctggcg tataaaacgt
    42001 aaggtcatca cgttccagat cgaaacggat ataatcggcg accctcatga tgacatgctc
    42061 gttggtctcc tcatctacgt agtcatagag gacacgttcg ccatatcgta cgatatagcg
    42121 cagaagagcc aactcataag cctcaaaagg agaacgtttc ggttggacct gtatgttggg
    42181 agccgtcgga acctcgtagg gaggagtagg gggcggaccc gcttcctctt ccggaatata
    42241 gtcctcgggc ggtggaggcg gaatattttc cggaagaagg gtattcgcct cttcctgtgt
    42301 atacggttgg tagccgggga aatccggata ctccggaatc gtattgacgg gagattgaac
    42361 gggcggtgta ttccttacgg atttagccgc ttggttctct tccttgttga gacggatctt
    42421 attgacctcg ttgagtaaga cttgctcgtc tatctccatg gtcgtactac attcccggat
    42481 atacacggag cgagcgatat tatcaggtat gatcgctacc gtacggataa tatccgagat
    42541 cagggcggaa cgtttgatcg gatcgctccc cgcttccgcc aatagtaact ttgtcttgaa
    42601 acggatgaaa tccgtctcgt tctggctgat aaactcggcg aactcgctcg cgctatggct
    42661 acgggcaaac gagtccggat cttctcccgc cggaagaagc acgaccttga cgttcatccc
    42721 ttcttccaat aacatatcga taccccggag agccgctttg attccggcgg cgtctccatc
    42781 gtataatacc gtgatattat tcgtgaaacg atgtatgagc cggatttgcc cttgcgtgag
    42841 cgccgtaccc gaggaggcaa ccacgttttc tacgcccact tggtgcatac cgatcacgtc
    42901 catatatcct tccaccaaga aacagcgatc ctgtttcatg attgcttgct tggcgaaata
    42961 gatgccgtaa agctcgttgc ttttatgata aatctcgctt tcgggggagt ttacgtactt
    43021 cgcggtcttc tcgtcctttt tcaatacacg tccgccgaat gccacgacct ttccgcttaa
    43081 cgtatggacg ggaaagataa cacgtcctcg aaaacgatcg ttcacgtttc cgttatcata
    43141 agcgataact aaaccggttt tctcgaggaa ttccttttta taacctgctt ttatagcggt
    43201 tttgtataaa gcatcccgct ggtccaagct atacccgagc tggaatttac ggatgatatc
    43261 ttccctcaat cctcgctcgg cgaagtagcg catacctacg cttttccctt caacatgctc
    43321 atgtaataaa gtagagaagt attgccccgc ccaactattg acgataagca tactttcccg
    43381 gtcgctacgg atttgtttct ctttctcggt aagttcccgt tcctgtatct ctatattgta
    43441 ttttttcgcc agaaagcgta aagcgtcgaa atagctgagt tgctcatgct tcatgatgaa
    43501 gtgaacggcg gttccacctt ctccgcaagc gaaacactta cagatattct ttgaggggga
    43561 tacgtaaaaa gacggtgatt tgtccgaatg aaatgggcat aatcctacat agttgatccc
    43621 tcgtttccga agagtcacga attcagagac aacatccacg atgttcgccg cgtccaatat
    43681 ccggtctatg gtaggttgat cgatcatttt aaattactct ttattttagc gaacacaaat
    43741 gtagtgaaaa ataaccaaac acaaacaagg cttgatgttt gcttgtgttt ggttattttt
    43801 tgctatattt gcggcgtgaa acgaatgcta
//
LOCUS       DBMDTB010000024        42354 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_370_length_42354_cov_12.229640, whole genome shotgun sequence.
ACCESSION   DBMDTB010000024 DBMDTB010000000
VERSION     DBMDTB010000024.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 42354)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 42354)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42354
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_370_length_42354_cov_12.229640"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            401..1921
                     /gene="guaA"
                     /locus_tag="ACZPB4_05945"
     CDS             401..1921
                     /gene="guaA"
                     /locus_tag="ACZPB4_05945"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015532441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HIR1097796.1"
                     /translation="MHEKLIILDFGSQTTQLIGRRVRELNMYCEIVPYNKFPHDATDV
                     KGVILSGSPYSVYDENAFKADLTEIRGKYPVLGICYGAQFLAYTSGGNVEPANSREYG
                     RANLSHIDGEDELLKGIHVGSQIWMSHGDTITVLPDNFKVIASTDDVRAAAYHVEGEQ
                     TWGVQFHPEVFHSTDGTKLLDNFLNICGCAKDWTPASFIESTVAELKEQLGDDKVILA
                     LSGGVDSSVTAVLLNKAIGKNLTCIFVDHGLLRKNEFENVMRDYEHLGLNVIGVNAKD
                     KFYKELAGVTEPEKKRKIIGKGFIDVFDEEAHKLKDIKWLGQGTIYPDVIESLSITGT
                     VIKSHHNVGGLPDTMNLKLVEPLRLLFKDEVRRVGMELGMQPHLIKRHPFPGPGLGIR
                     ILGDITPEKVRILQDADDIYMSLMREWGLYDKIWQAGVILLPIQSVGVMGDERTYENT
                     VALRAVTSTDAMTADWAQLPYEFLAKVSNEIINKVKGVNRVVYDISSKPPATIEWE"
     gene            1973..3280
                     /gene="guaA"
                     /locus_tag="ACZPB4_05950"
     CDS             1973..3280
                     /gene="guaA"
                     /locus_tag="ACZPB4_05950"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004309046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HIR1097797.1"
                     /translation="MKQDMIVILDLGSHENTVLARAIRALGVYSEIYPHDITVEELKT
                     LPNVKGIIINGGPNNVIDGVAIDVNPGIYEMGTPVMAAGHDKALCEVKLPEFTDDVEA
                     IKGAVKSFVFDTCKAEANWNMTNFVNDQIELVKRQVGDKKVLLALSGGVDSSVVAALL
                     LKAIGDKLVCVHVNHGLMRKGESEDVVEVFKNQLNANLVYVDATDRFLNKLADVEDPE
                     QKRKIIGGEFIRVFEEEARKLDGIDFLAQGTIYPDIVESGTKTAKMVKSHHNVGGLPE
                     DLQFELVEPLRQLFKDEVRACGVELGLPYDMVYRQPFPGPGLGVRCLGAITRDRLEAV
                     RESDAILREEFKNAGLDKKVWQYFTVVPDFKSVGVRDNARSFEWPVIIRAVNTVDAMT
                     ATIEPVDWPILMKITDRILKEVKNVNRVCYDMSPKPNATIEWE"
     gene            complement(3369..4106)
                     /locus_tag="ACZPB4_05955"
     CDS             complement(3369..4106)
                     /locus_tag="ACZPB4_05955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-disaccharide hydrolase"
                     /protein_id="HIR1097798.1"
                     /translation="MKKLFKSFLILSAIAMAIPCFAQTPNTLTKKEKKAGWELLFNGK
                     DFSGWRQCNGTAMPANWVIEDNAMKVFTGEGKKPGQGANGDILYQNKKFKNFELSVDW
                     KASKMGNSGIFYYVREVPGKPIYYAAPEVQVLDNVDATDNKLANHLAGSLYDMLPADP
                     KTVNPAGEWNTIVIRVKDGKVTHTQNGKKVVEYTLWSKEWDDLVANSKFKNFPGFTEG
                     ISKEGYIGLQDHGYPIWFRNIKIRELK"
     gene            complement(4872..5570)
                     /locus_tag="ACZPB4_05960"
     CDS             complement(4872..5570)
                     /locus_tag="ACZPB4_05960"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010800152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HIR1097799.1"
                     /translation="MQIFYTPDIAIKPELPEEEAGHCIRVLRLGEGDEIVLTDGQGSF
                     YKAAISRAHPKHCEVTLLESWKQPDLWNFNLHIAIAPTKNMDRMEWFVEKATEIGINA
                     ITCLNCRFSERKEIKPIRLEKILVSAMKQSQKATLPALEGMTDFKKFVATPFDGRKFI
                     AHCEEGEKPLLKHTYQPGENALILIGPEGDFSPEEIKLAQENGFEPISLGESRLRTET
                     AALVACHTIHVLNQ"
     gene            complement(5609..6925)
                     /locus_tag="ACZPB4_05965"
     CDS             complement(5609..6925)
                     /locus_tag="ACZPB4_05965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005337 - nucleoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:1901642 - nucleoside transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HIR1097800.1"
                     /translation="MIGEQGGFGLVSLLRGLLGIITILGIAYAMSYDRKRIDWKLVGG
                     GLFMQIVFALAVLYVPFVGSLLEGCGKIFVKLMDFTDAGLTFLLGPYASKAAGFSFLL
                     HSLPIVIFFSALVSMFYHWGIIQKVVGAFAWVLRKFMNISGSEGLVAAGNIFMGMTES
                     PVLIKNYLPTMNRSEIFLVMVSGMGTIAGSVMGTYIGMLGGTDPASKVLFATHLLSAS
                     VMAVPGSIVLAKMLCPQTEEATDHVAVSGKEKENSNILDAISSGTVTGVKLMTNIAAM
                     LLVFISLVALANYVTEDVIGRYTGLNDWIVQISDGKAKGLTFQFILGVITAPFMWLIG
                     VPGQDIMLVGSLLGQKTILNEFVAYFQLQQWKDAGLFMYEKSILMSTYILCGFANISS
                     IGILLGGLGVLAPEKRGLISRIGVPAMIGGALVSVLSATIIGMILG"
     gene            complement(6922..7563)
                     /locus_tag="ACZPB4_05970"
     CDS             complement(6922..7563)
                     /locus_tag="ACZPB4_05970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional nuclease family protein"
                     /protein_id="HIR1097801.1"
                     /translation="MSTRIKLRVQGLANSQIQSGAYALILAEENGPRRIPIIVGTAEA
                     QSIAIALEHIVPPRPLTHDLFATFAQAFNVILKEVYIYKFEDGVFYSELEFSDGERSI
                     KLDSRTSDAIAIALRVKCDIFTSEEIVKECGVVLEDTLSIPADEPEEDDNLLELEPDE
                     IKDEAQLKKWLSLLDIQEINERLEDAIADENYEYAKMYKDELRRREEEEDTNK"
     gene            complement(7636..8274)
                     /locus_tag="ACZPB4_05975"
     CDS             complement(7636..8274)
                     /locus_tag="ACZPB4_05975"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1097802.1"
                     /translation="MNAIVGFSNLMNTDIELSKAERENFTELINTNSDLLLNLINDIL
                     DLSRIESGRMSFSFQQYSLNELISTIYQTFQVLMPENVELRMQIPEKSISIPTDKFRL
                     TQVITNFLSNAIKFTQKGYILIGYEYREEERHVHIFVEDTGIGIPKEKQDAVFNRFTK
                     LDEFAKGTGLGLSICKVIAERFDGYIAVESEIGKGSRFSIILPLNPKHTESD"
     gene            complement(8697..9494)
                     /locus_tag="ACZPB4_05980"
     CDS             complement(8697..9494)
                     /locus_tag="ACZPB4_05980"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metallopeptidase"
                     /protein_id="HIR1097803.1"
                     /translation="MKKILLSLAFLAGVSLTVSAQFKIGGKTINTKKVINAATDVAHA
                     ATLSDEDVAKMAKEYIQWMDTHNEVAGPDTEMGQRLERLTANVKKVSGLDLNFKVYNV
                     VDVNAFACGDGSVRVCGGLMKIMDDDEVFAVIGHEIGHVVHSDSKDAMKNAYLTSAAK
                     NAAGAVSGTVSKLTDSQLGDMAQALAGAQYSQKQEYEADEFGFQFCIDYGRDPYGMSN
                     SLNKLLQLSESEAKSSKFMQMFSSHPETQKRADRVKEKADEYVKSKQ"
     gene            complement(9503..10432)
                     /locus_tag="ACZPB4_05985"
     CDS             complement(9503..10432)
                     /locus_tag="ACZPB4_05985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010183564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5106 domain-containing protein"
                     /protein_id="HIR1097804.1"
                     /translation="MNMKYLYVLLLTLTVNACSGQRNQKTEESNVAPPTFEMVSVPTL
                     ITDPVERAEYLVKHYWDKFDFKDTTYIHEPQVTEQALSNYIDLMNYVSPAAMSSSVKA
                     MMKQTEQDSAMFQYFSEMMEKYLYDPNSPLRNEEMYIAVLEYLTESSSLSDVEKIRPA
                     HLLELALKNRIGTPATDFTYTLANGQTGKLYNIKADYLLLFFYNPDCHACQEITRQME
                     SSFLINEFSKSNKLKILAVYPDEDLDAWKEHVSVMPKDWINPYDKSVSLKNDEIYDLK
                     AIPTLYLLNKEKKVLLKDATFQQIENYLSQTTN"
     gene            10514..11401
                     /locus_tag="ACZPB4_05990"
     CDS             10514..11401
                     /locus_tag="ACZPB4_05990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001216 - DNA-binding transcription
                     activator activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HIR1097805.1"
                     /translation="MDFRLKVFHSVACNLSFTKASRELFISQPAISKHIHELEVQYKT
                     PLFERTGSQIRLTRAGELLFSHTHSLLASYRQLDFEMNLLTNNFLGDLHLGASTTISQ
                     YVLPPVLALFIKMFPDIHVSVLNGNSRDIELALRDGKITLGLVEGTTRQNTMHYIPFM
                     KDELVVVTHVGSKLAAYDELTLEQLCALPVVLRENGSGTLEVLEGALAKHQIKLSQLN
                     VLLQLGSTESIKLFLENSDALGILSIRAVTRELMAGRLKVIDIEGFKAERTFSFVEPQ
                     GQNSGMEESFMRFASQHWQ"
     gene            11511..12566
                     /locus_tag="ACZPB4_05995"
     CDS             11511..12566
                     /locus_tag="ACZPB4_05995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family protein"
                     /protein_id="HIR1097806.1"
                     /translation="MFSEKRGNVLHGVLLIALFSCSAFYIAEFQFVKQMSFSPLIVGI
                     ILGMLYANSLRNHLPETWVPGILFCTKQVLRAGIVLYGFKLTFQSVIAIGLPAILIDM
                     VIVVLTILIGVWVGRLMKMDKDLALLTATGSAICGAAAVLGAEPVVKCEAHKTAVAVS
                     TVVIFGTLSMFIYPVMYRAGILDLDPEQMGLYTGATLHEVAHVVGAGNAMGKEISDAA
                     IIVKMIRVMMLAPVLVVMSFMLARTAVNSVVNGGRNGGGVAPSRGKITIPWFAFGFLA
                     VIGFNSLDLLPHAVVDGINQVDTFMLTMAMTALGTETSIEKFKKAGAKPFVLATILYV
                     WLLAGGYLLAKYVPQLA"
     gene            12653..14998
                     /locus_tag="ACZPB4_06000"
     CDS             12653..14998
                     /locus_tag="ACZPB4_06000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HIR1097807.1"
                     /translation="MASKITKGILISCWIVYLAILGAVVMVFMAIANGSIGYMPPVEQ
                     LENPIDKYASQVISSDGKALGAYAHSKDNRIYVNYEDLSPDLVKALIATEDIRFAEHS
                     GIDAQGLFRAIVKRGILMQKSGGGGSTITQQLAKQLFSPSADNMMERLFQKPIEWVIA
                     VQLERYYTKEEIINMYLNKFDFLYNAVGIQSASRVYFGKTPKTLKIEEAATLVGMCKN
                     PSYFNPVRHNKRTIGRRNTVLEQMEKAGYITKAECDSLKALPLVVHFTRMDHKDGLAP
                     YFREYLRLTMTAKKPERKDYASWQSQKFSEDSLSWATNPLYGWCNKNKKADGEYYNLY
                     TDGLKIYTSIDSRMQKYAEDAVREHMSKDLQPAFFREKKGRSYAPFSRDVSVGQVDTM
                     LMRAMHQTDRYRAMKKSGMAEADMRKEFEKPVDMRVFSWDGPIDTIMSPLDSIRYHKS
                     FLRTAFMSMDPRTGQVKAYVGGIDYNDFQYDMVNGGRRQIGSTMKPFLYSLAMIEGIS
                     PCDQMLHVQQQLMDENGRLWVPRNASAKRIGEMVTIKWGLQNSDNWVTAYLMSQLSPY
                     TFVRLLHSFGLKNHIDPVISVCLGTPDVSVGEMVGAYTVFANKGIRVEPLFVTRIEDS
                     YGNTIANFTPQMSEVLTEDASYKMLHMLKSVIDGGTGGRVRFRYGIKAEMGGKTGTTQ
                     NNSDGWFMGFTPSLVSGCWVGGEDRSIHFDRLAEGQGASMALPIYALYMQKVYKDKTL
                     GYSEDETFEIPEKYANPCSEGGEEDSPTTPPDTGGIDKMFE"
     gene            15229..16794
                     /locus_tag="ACZPB4_06005"
     CDS             15229..16794
                     /locus_tag="ACZPB4_06005"
                     /EC_number="1.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0004368 - glycerol-3-phosphate
                     dehydrogenase (quinone) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate dehydrogenase/oxidase"
                     /protein_id="HIR1097808.1"
                     /translation="MDRSKMISQLEDPSEVFDFLVIGGGATGIGIALDASTRGYRVAL
                     FEQSDFTKGTSSRSTKLVHGGVRYLAQGDVSLVLEALRERGLLRQNAPHLVKDQTFLI
                     PCYRWWEGPFYTIGLILYDVMAGKLGLGRSVCIGPKRALRTIPMLRPKGMTAGVLYHD
                     GQFDDSRLAINMVRSSIDAGACILNYAKVIGLLKDGDRKVSGVTVRDEETGTVYQVRS
                     RCVINATGVFADEILQMDEPGKRPTVRPSQGVHLVLDSSFLQSDCAIMIPKTSDGRVL
                     FAVPWHDKVVVGTTDTLMESPEKEPVALEKEIQFILDTAANYLTRPPKRSDVLSVFAG
                     LRPLAAPRSEGKKTKEISRSHKLIREKSGLITIIGGKWTTYRKMAQDTLDLAIRYMHI
                     PTKDCITERYQIHGSRKNPDFSDPLYVYGTDADEIRNLVASSPAMAEKLHPDYAYTVG
                     EVTWLVRNEMPRTLEDVLARRLRILFLDARAAMAMAPKVAGILATEWGKDETWTSAQV
                     KAFNEVASNYILN"
     gene            16827..18326
                     /gene="glpK"
                     /locus_tag="ACZPB4_06010"
     CDS             16827..18326
                     /gene="glpK"
                     /locus_tag="ACZPB4_06010"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HIR1097809.1"
                     /translation="MNFRNKYVLAIDQGTTSSRAILFNHQGTIITLAQKPFQQYFPKP
                     GWVEHDPNEIWYTQSSVIKEAMAKADVTDSHIACIGIANQRETTIIWDRETGFPVYNA
                     IVWQDRRTADYCEELKSQGWAERILQKTGLVIDAYFSATKIKWILDNVKGIRERAERG
                     ELCFGTVDTWLVWKLTRGAQFITDVTNASRTMLFNIRTLQWDQELLDLFTIPASMLPQ
                     VKACSEVYCETSTPIFKKGIPVSGMAGDQQAALFGQLCVEDGMIKTTYGTGCFMILNT
                     GKEPVLSQNNLLTTIAWKLGDQTTYALEGSVFVGGAVVQWLRDGIGLIPNASITEQMA
                     KSVSDNGGVYFVPALTGLGAPYWDQYARGAIIGITRGTTAAHLTRAALEGICYQVYDV
                     LMAMENDIHAKPKEIRVDGGAIANNFLMQFQSDICRCPVVRPNVLETTALGAAYLAGL
                     AIGYWKDIDELKEQWCLDKVFNPQMKEDTARKLLNEWHKAVGRSQNWAE"
     gene            18383..19120
                     /locus_tag="ACZPB4_06015"
     CDS             18383..19120
                     /locus_tag="ACZPB4_06015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HIR1097810.1"
                     /translation="MSPFLAELLGTMLLILMGGGVVANVCLSKTKGNGAGWIAITTAW
                     ALGIFIGVVVAGPYSGAHLNPAVSIGLAIGGTFPWCDVCTYIAGQMIGAALGALLVWL
                     VYKDHFNATDDPDAELGVFCTSPAIKDYPINFLGEMIGTFALMFVVFFITDGELTYES
                     NSTLPIGLGSVGAIPVAFTVWVIGLSLGGTTGYAINPARDLAPRFIHFILPIKGKGSS
                     HWEYAWVPVLGPIAGAAIAGMLYYVLK"
     gene            complement(19086..19565)
                     /locus_tag="ACZPB4_06020"
     CDS             complement(19086..19565)
                     /locus_tag="ACZPB4_06020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation protease"
                     /protein_id="HIR1097811.1"
                     /translation="MKAEKETLVLGVGNLLLKDEGVGIHVIKALENEKLPAHVHLMDG
                     GTGGLHLLSWLQGYDRIIMIDATLDNNLPGTVRLIQPRYATDFPPLMSAHEIGLKDMI
                     DAMILTDDLPETHLIVISTLNINEVGMDLTPEVKAAVPKVIRMIQEIISIHNRAYRQ"
     gene            complement(19562..20299)
                     /gene="cybH"
                     /locus_tag="ACZPB4_06025"
     CDS             complement(19562..20299)
                     /gene="cybH"
                     /locus_tag="ACZPB4_06025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_process: GO:0022904 - respiratory electron transport
                     chain [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Ni/Fe-hydrogenase, b-type cytochrome subunit"
                     /protein_id="HIR1097812.1"
                     /translation="MKIRKKRLREVYVWELPVRIYHWVNALCIVILCVTGFIIADPPA
                     IMSASEAYFSYWFGVVRFIHFVTAFVFFFNFVFRLYWGFVGNRYARWNNFIPLKKSQW
                     KEVLEVIKVDILMIKNKPVDSIGHNALASLIYFGTFWAFLLQSITGFGLYAKMSQSFF
                     PQLFAWTVPLMGGDLMARQIHHFLMWFFILFAIVHIYLVFYHDYIEQRGETSSIIGGW
                     KFIEEDIADKEEVTETAETITKIAKKG"
     gene            complement(20314..22035)
                     /locus_tag="ACZPB4_06030"
     CDS             complement(20314..22035)
                     /locus_tag="ACZPB4_06030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel-dependent hydrogenase large subunit"
                     /protein_id="HIR1097813.1"
                     /translation="MSERIVIDPITRIEGHLRVEAEIEGGTIKNAYSSGTMVRGIENI
                     VKDRDPRDVWAFVGRVCGVCTSIHSLASVRAVENARGIVIPPNASMVRNIMQAVLYMH
                     DHTVHFYQLHALDWVDVVSALKADPKAAALLAQQLSPWAKNTEGYFTATQQRLKKFVA
                     SGQLGIFANGYWGHPDYKLTPEQNLIATVHYLDALEWQKEVVKVHAVFGGKNPHPNYI
                     VGGMPCSIDLNEANAINADRLALVKQKLEEAKTFINQVYIPDLLMIANVYKDKWSKIG
                     GGVRNYLSYGDYPMFDLGEVESYKIPRGIVLDRDLSKVHPVDANSPEEIKEYIYHSWY
                     KYTQGDKAGLHPYEGETHLEYTGPRPPYKLLDVEDKYSWIKTPRWKQEPMEVGPLARL
                     IVAYAAGKEPQKSIVDETLRQLDLPVDALFSTLGRTAARGLECRMAADWALEFFNQLI
                     KNLENGDSRMANSAEWERENWPDHEQGVGLAEAPRGALAHFIVIDKNRVKNYQMVVPT
                     TWNASPRDENGVLSAYESALIGTPIYDPKQPLEILRTIHSFDPCLACAVHLYDEEGKY
                     VHQVDTF"
     gene            complement(22051..23148)
                     /locus_tag="ACZPB4_06035"
     CDS             complement(22051..23148)
                     /locus_tag="ACZPB4_06035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008157834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase small subunit"
                     /protein_id="HIR1097814.1"
                     /translation="MENKRPSVYEECRQKGISRRDFLKFCTTMAALMGLEASGVAQVV
                     NALETKPRLPIIWLHLQECTCCTESFIRAAHPIVATLLLDKISLDYTETLMAAAGEQA
                     EAAKEETMKKYYGNYLLMIEGSLPTKDEAYCCVGGKSALQITEEAAAGAKAIIAWGNC
                     ASAGCVQAANPNPTGAKGIHKVIKGKPIINVQGCPPIADVMAGVIIYMLTFDRMPQLD
                     GLGRPKMFYSRRVHDTCYRRANFDAGLFVESFDDENAKHGYCLYKVGCKGPSTYNSCG
                     IIKWNEGTSYPIQSGHPCLGCSEENFWDNSPFYKRMPDIHGFGIEATADQIGLALGAA
                     TAAGIAVHAVATNIRKKELIDNDEPESKSTI"
     gene            complement(23168..24217)
                     /gene="hypE"
                     /locus_tag="ACZPB4_06040"
     CDS             complement(23168..24217)
                     /gene="hypE"
                     /locus_tag="ACZPB4_06040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase expression/formation protein HypE"
                     /protein_id="HIR1097815.1"
                     /translation="MDIHLNCPIPFTDSDRVLLAHGGGGRMTHQLISQVFYPAFRNPL
                     LEQDHDGCVFPMEEGRLAYSTDSFVVDPIFFPGGDIGDLAINGTVNDLACCGARPLYL
                     TAGFILEEGLPLADLQRIVQSMKRAAERAGVQIVAGDTKVVERGKCDKLFINTSGIGI
                     VPPGIRIAPDQATPGDVVICSGPIGLHGITILSARESLGFETDLKSDTASLNIMISEL
                     LHTIGEVHVLRDPTRGGVSGTLNEIAQDAGVDILLDEDALPIPEAVRAASEMLGLDPL
                     YIANEGLVLVILPESLAEQALPLMRCFEEGRQATVIGRITKQSGEQARVKMKTLYGNY
                     RIIDMLSGEQLPRIC"
     gene            complement(24224..25303)
                     /gene="hypD"
                     /locus_tag="ACZPB4_06045"
     CDS             complement(24224..25303)
                     /gene="hypD"
                     /locus_tag="ACZPB4_06045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016530 - metallochaperone activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase formation protein HypD"
                     /protein_id="HIR1097816.1"
                     /translation="MRFVDEYRSNEKVQTLLEAIRKKVTRPWYIMEICGGQTHAIARY
                     RLEEMLPPDIQLLHGPGCPVCVTPVETIDYALKLATQPNVILASFGDMMRVPGSKEDL
                     LSVKARGADIRMLYTPLDALSLAEENPDKEIVFFAIGFETTAPVHLMALKEAIRRGLP
                     NFSILTSLFTVPPAIEAILSDPESKVNGFLTAGHVCAITGNRAYHRLAAHYKIPMVVT
                     GFEPVDLLYGIYRCVSQLEAGSYEVENAYKRAVPEQGNAAARQLIDEMLEPCDQDWRG
                     IGIIPSSGLQLRSEYKRYSSRMRFQLCPEENQIASECIAGLIMRGLRQPSDCPHFGKA
                     CHPTHPLGAPMVSSEGVCAAYYRYK"
     gene            complement(25291..25524)
                     /locus_tag="ACZPB4_06050"
     CDS             complement(25291..25524)
                     /locus_tag="ACZPB4_06050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0051604 - protein maturation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HypC/HybG/HupF family hydrogenase formation
                     chaperone"
                     /protein_id="HIR1097817.1"
                     /translation="MCLAVPGKIISIDRSIPEMTMAKVDFGGILKNICIEWVDVKQGD
                     YILAHAGIAISVVDEKEAEETLKDLKELQKCVS"
     gene            25684..27966
                     /gene="hypF"
                     /locus_tag="ACZPB4_06055"
     CDS             25684..27966
                     /gene="hypF"
                     /locus_tag="ACZPB4_06055"
                     /EC_number="6.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003998 - acylphosphatase activity
                     [Evidence IEA];
                     GO_function: GO:0016743 - carboxyl- or
                     carbamoyltransferase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyltransferase HypF"
                     /protein_id="HIR1097818.1"
                     /translation="MAKNKVYALIIQGLVQGVGFRPFIYRIAKDLGMKGCVENMNNGV
                     RILVAATPDDRDLLISRIRTEHPRVAYIHRISYTSTEMDEDDFDDFTITPSHSESDEV
                     TQVSPDIAVCADCMRDRTTQPHRIGYPFINCTHCGPRFSIIRDLPYDRSQTTMGGFLM
                     CPDCEKEYTNVIDRRFHAQPVACNHCGPTYYATYNEETYIDYETLLKLTSRLLLGGEV
                     IAAKGIGGYHLICDASNERAVARLREIKQRDTKPFAVMFRDLEHLQVYTATEPMEERC
                     LVSWRRPIVLLRQRSRLASGINPGMHTLGCMLSYMPIHYDWFARTGIPALVMTSGNLS
                     DLPIAITPEDAEAQLAGKVAVLLHHNRPIHNRVDDSVLQVCGGQPCLIRRSRGYVPEP
                     FFTDTNVEGIMAFGAEKVNTFALGKGETILQSQYIGDLKNWETFRFYTESMERFRHLF
                     RFNLQRLVCDLHPDYLSSQEAERISKSLSLPLLKVQHHHAHAAACMLEHGLNEPVLAI
                     VMDGTGLGDDGKVWGGEFFFCDRAKYRRLSHFEYVPLPGGDKAAEEPWRMVVAYLWHY
                     FKDEPSGIPYPADFVERIGTERIAMLERMMEKGVNTPYTSSAGRLFDAVASLLGICDV
                     SSHQAEAPVLLEQAAMGERNAYAYPVSAEGEEISFYSLFEALLHDKTNEVPVSLISAR
                     FHTTLASLFVQKARLLIKRTKATQVVISGGCFQNKLLTESMRRQFIMAGVPVYIPSRI
                     PCNDGGIAVGQLTIASVTPF"
     gene            27979..28326
                     /gene="hypA"
                     /locus_tag="ACZPB4_06060"
     CDS             27979..28326
                     /gene="hypA"
                     /locus_tag="ACZPB4_06060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008901 - ferredoxin hydrogenase activity
                     [Evidence IEA];
                     GO_function: GO:0016151 - nickel cation binding [Evidence
                     IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation nickel metallochaperone
                     HypA"
                     /protein_id="HIR1097819.1"
                     /translation="MHELSIARSIVELVEEQADNRGASVVEELELEIGHLSGVEIQTL
                     AFALDSAIKGSKLEKARIIRHYIEGEGQCSDCETIFPMNALFSPCPHCGSYLVKILKG
                     KELRMKSIVIKKE"
     gene            28356..29108
                     /gene="hypB"
                     /locus_tag="ACZPB4_06065"
     CDS             28356..29108
                     /gene="hypB"
                     /locus_tag="ACZPB4_06065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0016151 - nickel cation binding [Evidence
                     IEA];
                     GO_function: GO:0016530 - metallochaperone activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0051604 - protein maturation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase nickel incorporation protein HypB"
                     /protein_id="HIR1097820.1"
                     /translation="MCGTCGCGEHHHHHDHTHEHSHGHEHHHHPDEGIVINLEQDILQ
                     RNNLLAERNRGYFEAKNLFCLNLMSSPGSGKTTLLEETIRRLKAKRPIYVIEGDQQTS
                     NDADRIAALEIAVFQVNTGTGCHLEADMVNHAVKHLNPKEGAILFIENVGNLVCPAMF
                     DLGESKKVVIVSTTEGDDKPLKYPHIFQEADICVINKIDLAPYLNTKVEVLRENALKV
                     NHHLQIFEVSATKGDGMDAWCDWLQTESAKCK"
     gene            29188..31248
                     /locus_tag="ACZPB4_06070"
     CDS             29188..31248
                     /locus_tag="ACZPB4_06070"
                     /EC_number="6.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008157823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0043758 - acetate-CoA ligase (ADP-forming)
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetate--CoA ligase family protein"
                     /protein_id="HIR1097821.1"
                     /translation="MINRELINPQSIVVVGGSNNVHKPGGRIVRNLLDGKYKGELCVV
                     NAKETDVQGVKSYPSVHDIPETELAIISIPSKSCPEVMEVLARQKGVKAFIVISAGFG
                     EETHEGGILEQQMLDVVNEAGASLIGPNCIGLMNINYHGVFTQPIPEFHPDGVDFISS
                     SGGTALFIIESALTKGLRFSSVWSVGNSKQNGVEDILEYMDRNFDPVLDSKIKMLYIE
                     QIKQPDKLLYHASSLIRKGCKIAAIKAGSTESGKRAASSHTGAIASSDSAVEALFRKA
                     GIVRCFSREELTTVASIFTLKDVKGKNCAIVTHAGGPAVMLADALSKGRLNVPSLEGP
                     IADELKSKLYPGAAVGNPIDIIGTGTPEHLATAIDFCENRFDNVDLMMVIFGSPGLVK
                     LYDTYEVLHKKMEECKKPIFPILPSIVTAGPEVKSFVKKGHVNFSDEVTLGTALSRVI
                     NTPKPMSTDIQLYGVDVPEVRRIIDRLPGSGYLNPEEVRTLLRAANIPLVEEYASDDR
                     DALLAFAKKVKYPVVAKVVGPVHKSDIGGVALNIRGEEHLLFEYERMMRLPGVTGIMV
                     QPMLKGQELFLGAKYEDRFGHVVLCGLGGIFVEVLKDVSYGLAPLSYDETYSMIRSLR
                     GYPIIKGTRGQKGIDEQQYADIIVRLSTLLRFASEIKEMDINPLVATDRGLFAVDARI
                     RIEK"
     gene            complement(31311..31928)
                     /locus_tag="ACZPB4_06075"
     CDS             complement(31311..31928)
                     /locus_tag="ACZPB4_06075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HIR1097822.1"
                     /translation="MTIAFIRTYNNKQNSEVQEAVIREFAESQKIEIGKWAKEVGNSP
                     RANRRLESIVKSLSPGDEILVSDISRVSRKMIEIIHIILLCIERKVTLRSVSDGYVFE
                     DNIDSKTLAFTFGLVSEIERKLVSIRTKEALALIRSKGVVLGRPKGSQQMGRLEPYKE
                     QIEKDLKDPSLTYAQIAEKYNVSLSSFKRFLKEYLPDKKKKKTKK"
     gene            complement(32068..32154)
                     /locus_tag="ACZPB4_06080"
     tRNA            complement(32068..32154)
                     /locus_tag="ACZPB4_06080"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(32118..32120),aa:Ser,seq:gct)
     gene            32294..33343
                     /gene="mltG"
                     /locus_tag="ACZPB4_06085"
     CDS             32294..33343
                     /gene="mltG"
                     /locus_tag="ACZPB4_06085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008932 - lytic endotransglycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HIR1097823.1"
                     /translation="MDLNKQILSRRPIIIALIAILVVLIGGGGFWVYRLAWAPNFKPD
                     KTVYVYIDDKKDFDDLCRQLRDSANCLRIGSFKQLSGLLKYPASMRTGRYAVKPGMSN
                     LTLLNDLRRGHQVAARVTFNNIRFKEDLAERISDQLMFGKENLLRLLNDSVYCDSLGF
                     TPETINALFIPNTYEIYWNISADKFIRRMKREYDAFWTPERLKQAEEIGLTPVEVSIL
                     ASIVEEETAASDEYPIVAGLYINRLHAGIPLQADPTVKFAVGDFSLRRILFEHLEIDS
                     PYNTYKYAGLPPGPLRIPTIKGLNSVLNHTKHKYLYMCAKEDFSGRHNFAVTLAEHNR
                     NANRYRAELNRRRIR"
     gene            33448..35049
                     /locus_tag="ACZPB4_06090"
     CDS             33448..35049
                     /locus_tag="ACZPB4_06090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent enzyme"
                     /protein_id="HIR1097824.1"
                     /translation="MEKHLFLGDEAIAQAAIDAGISGVYAYPGTPSTEITEYIQGSPV
                     TKERGIHCRWSANEKTAMEAALGMCYAGKRALCCMKHVGLNVAADCFMNAAMSGINGG
                     MIILTADDPSMHSSQNEQDNRIYGNFAMIPMFEPSSQQEAYDMVYHGFELSEKLGYPI
                     LLRVTTRMAHSRAGVVTSPLKPENRMNCPEDGRQRFILLPALARKRFKSLLASQEAFT
                     EASENSAYNKYFDAPNKDLGIITTGIAFNYLSENYPDGFEHPVLKISQYPLPRKQVEK
                     IVGECKEILVLEEGYPVVEEQLKGFLAKGVTVHGRLDGTLQRDGELTPDAVGKALGKE
                     IQSYYAIPEVVEQRPPALCQGCGHRDMYEALNEVIAEYNGTAKVFGDIGCYTLGALPP
                     FRAIDSCIDMGASITMAKGASDAGVFPAISVIGDSTFTHSGMTGLLDCVNENTNITIV
                     ISDNETTAMTGGQDSAGTGRLESICAGIGVDPAHIRVMVPLKKNFEEMKSIIREEIEY
                     KGVSVLIPRRECIQTLTRKKKASKK"
     gene            35046..35627
                     /locus_tag="ACZPB4_06095"
     CDS             35046..35627
                     /locus_tag="ACZPB4_06095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate oxidoreductase subunit beta"
                     /protein_id="HIR1097825.1"
                     /translation="MKTDIILSGVGGQGILSIAAVIGEAALKEGLYMKQAEVHGMSQR
                     GGDVQSNLRLSDEPIASDLIPKGHADLIISLEPMESLRYLPYLKKEGWLVTNSRPFVN
                     IPNYPEIEKVNAELDKLPHKVVLDVEEIAKEAGSVRAANIVMLGAATPFIGIEYDKIE
                     AGIRQIFGRKGEDIVNMNLKALKAGYDLAQSLR"
     gene            35841..36350
                     /locus_tag="ACZPB4_06100"
     CDS             35841..36350
                     /locus_tag="ACZPB4_06100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HIR1097826.1"
                     /translation="MKKYLLASLLALLAFVGKAQEDNSDIVKVGDTMPSFTIVSDNGS
                     KLQSASLKGKVILVNFFATWCPPCQKELAAVQQTLWPKYKNNKDFVLLVIGREHSDAD
                     LQKYNEKKGFDFPLYPDKDRAIFGAFAKNLIPRGYLVGKDGKIIYTSKGYTDEEFAEL
                     MTKIEGALK"
     gene            36356..37144
                     /locus_tag="ACZPB4_06105"
     CDS             36356..37144
                     /locus_tag="ACZPB4_06105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HIR1097827.1"
                     /translation="MKYSNIHLIYFSPTHTSAKIVYAIAEGMGATSMSESDVTCESLD
                     MEEYIDDELTIIAAPVYGGRVAETAMERFRMFRSAHHAPVVPVVLYGNRDYEDALKEL
                     CDLVSEQGFVPVAAGAFIGEHSFSRKGMPIAEGRPDESDLNQATEFGKKIIEELEKVS
                     CVECLSALEVKGNFPYRVKGPSTPQAPVTDNDLCTQCEYCVDVCPTHAISLADEGMYS
                     DPNQCIKCCACVKECPEGARTFDTPYTAMLHKNFSARREPEIFF"
     gene            37266..39692
                     /locus_tag="ACZPB4_06110"
     CDS             37266..39692
                     /locus_tag="ACZPB4_06110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-rhamnosidase-related protein"
                     /protein_id="HIR1097828.1"
                     /translation="MKTYLFLLLFVFQAFSLSSQISLKGYNQEKIDPSLFEGRWKARW
                     ISYPGEAPNVYGVYHFRKSFDLEVVPSRFIVHVSADNRYKLYVNGKLVSLGPARGDIY
                     NWSFETVDLAPYLKKGKNTLASVVWNYAERKPVAQISYDQTGFILQGNTGHEAVVNTD
                     TTWVCLRNKAYAPWTEWQVLGYYVAGPGEELEASAYPWGWEQPDYDDRKWEKAVRGME
                     GATKGSRDYPGRLLVPSPIPPMDSRIERLAKLRRSEGIECPQGFPYWPKALTIPANTE
                     VRLLLDNDYLTTGYFSLAFSKGKEAEIHIGYSEALYKQEEESTTKSYALNGKGHRDEL
                     TDKQFIGYGDKILADGGDNRLFTSLWWRTWRYVELKVKTASEPLVIEDMYGTFSAYPF
                     RNETTFSAPGHEELGRMLEIGWRTARLCANETYMDCPYYEQLQYFGDTRIQAMISMYN
                     TSDPYMVKNAIEQGRQSMVAEGITMSRYPSSVHQFISSFSLWWICMGHDYWMYRGDEA
                     YMKTLLPAYRQVLSWYEQWLKPDYSLSYVPHWFFVDWAAGFDYGEPIREKEGNSALQD
                     LMYIMTLEFAVEMEQAIGLPAMADHYRKIATEMRKTIRPKYWDAARNLFADTQDHRGY
                     SQHVNALAILTGVTKGEEAVKVMNQTLADTSLIQCTIYFRYYLNQALKASGLGDQFLD
                     NLQIWRDQMALGLTTWAEMPEPSRSDCHAWGASPNIEFYRILLGIDSDAPGFRKIRIA
                     PSLGKLKEVSGTIPHPLGSVTAAYKLDERGEGTARLVLPEGTTGIFIWDGKEIPLKPG
                     EQVISLSSRH"
     gene            39711..41441
                     /locus_tag="ACZPB4_06115"
     CDS             39711..41441
                     /locus_tag="ACZPB4_06115"
                     /EC_number="3.1.-.-"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA];
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0009166 - nucleotide catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HIR1097829.1"
                     /translation="MRRVYSIALLLLVALGLSATTKEVKLKLVETSDIHGNFFPYNFI
                     EQREWGGSLARVYSFVQEERRAYGDNLLLLDNGDILQGQPSAYYYNFMDTVSTHIASA
                     MMNYMGYNAGNMGNHDVEAGHAVFDRWIKQCDFPILGANIIRTSDRENYLKPYEVFER
                     DGVKIVVLGMITPAIPVWLPETLWQGLYFADMEETARKWMKIIQEKEKPDVVVGIFHA
                     GNEARTMSGQYREDASMEVAQRIPGFDVVMMGHDHRRYCGKVANIEGDSVLLINPASN
                     GRVVGSVDVVLKMEHGKVLDKQVSGVLTDVDKLEPSEEFMEKFAPQYKAVNDFVSEKV
                     GTFTESIATRPAYFGPSAFIDFIHSLQLELTGADVSFAAPLSFDAKIDKGDITISDMF
                     SLYKYENMLYTMNLTGAEIKGFLEKSYAMWTNRMKSPDDHVLLLKERKKGQENYVSFV
                     NFSFNFDSAAGIIYTVDVTKPKGEKITILKMADGKPFDENKTYKVALNSYRGNGGGEL
                     LTKGAGIPQDELKSRIIHSTDKDLRYYMIQYIKEKGVLSPQPLNQWQMIPQDWTRPAA
                     ERDCKFLFGE"
     gene            complement(41682..41906)
                     /locus_tag="ACZPB4_06120"
     CDS             complement(41682..41906)
                     /locus_tag="ACZPB4_06120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010182747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097830.1"
                     /translation="MKSCEMHLVLVLSDHVNVGKDPLYRPPKTQKAEEGRTTQTTVYP
                     HVKASGKFPGKNPRAQKAHLYAFKETFLEK"
BASE COUNT        10742 a         9071 c        10682 g        11859 t
ORIGIN      
        1 tgcgattgga aggcattgga caaataattt taatttgaac gcaaagatag ttcactttcg
       61 cttattaaca taacataccc acagggtttt cggactgacc cgctgttttc atggcttccc
      121 ttggccggat tcttaggggg atttgtggtt ttcctcttga ggtattcatc ttctaatggc
      181 tgttgcatga ttgtccacca tccgttgcat gatcatgcaa cagttggtgg acaatcatgc
      241 aacagatggt ggataatgaa tgtctcagga ggaaaggcgt aataggacaa gggaagatcc
      301 tttaaaagta tcgtgataag gaagaatatt tgcccagtgt gtttatgctt cccgaattta
      361 ttactacctt tgcgccactc aattaaataa tcataattgc atgcacgaga aacttattat
      421 tcttgatttc ggctcgcaaa caacccagct tatcggccgt agggtcagag agttgaatat
      481 gtattgtgag atcgttcctt ataacaaatt cccgcatgac gctaccgacg tgaaaggtgt
      541 gatcctttcc ggaagtcctt attccgtata cgacgagaat gcctttaagg ctgatttgac
      601 cgagatacgg gggaagtatc ccgtcttagg tatttgttat ggagcgcagt ttctagctta
      661 tacatccgga ggtaatgtgg aaccggctaa ttcacgtgag tatggacgtg ctaatttgtc
      721 gcacattgat ggtgaggatg aattactgaa agggatccat gtgggttcac agatatggat
      781 gtctcatggg gatacgatta ccgtattgcc ggataatttc aaggtgatcg ccagcacgga
      841 cgacgtgagg gctgccgctt accatgtgga aggtgagcaa acgtggggcg ttcagtttca
      901 tccggaagta ttccattcga cagatggtac gaagttgctg gataacttct tgaatatttg
      961 cggatgcgcc aaggattgga caccggcttc ctttatcgaa tctaccgtag ctgagttgaa
     1021 ggagcaattg ggagatgaca aggtgatctt ggctctttcc ggcggtgtgg attcatctgt
     1081 tacggccgta ttgctgaata aggcgatcgg taagaacttg acttgcattt tcgtggatca
     1141 tggtttgctg cgcaagaatg agttcgagaa cgtaatgagg gattatgagc atttaggatt
     1201 gaacgtgatc ggcgtaaacg caaaagataa gttctataaa gaactagcgg gtgttacgga
     1261 accggagaag aaacgtaaga tcatcggtaa aggatttatc gatgtcttcg atgaggaggc
     1321 gcataagctg aaagatatca agtggctggg gcaaggtacg atttatccgg atgtgatcga
     1381 gtcgctttct atcacaggta cggttatcaa gagccatcat aatgtgggcg gacttccgga
     1441 tacgatgaac ttgaaactcg tcgagccgct tcgtcttctt ttcaaggatg aggttcgccg
     1501 tgtcggtatg gagttgggta tgcaaccgca tttgatcaag cgccatccgt tcccgggacc
     1561 gggattgggt atccgtatct tgggtgatat cacgccggaa aaggtacgta tcctgcaaga
     1621 cgctgacgat atctatatgt cattgatgcg tgagtgggga ctttacgata agatttggca
     1681 agctggggta atcttacttc cgattcaatc cgtaggtgta atgggcgatg agcgtaccta
     1741 tgagaatacg gtagctttac gtgcggtaac ttctacagac gctatgaccg ccgattgggc
     1801 gcagcttccg tacgagttcc tcgccaaagt ttccaacgag attatcaata aggtgaaagg
     1861 cgtaaataga gtcgtgtacg acatcagctc gaagccgcct gcaaccatcg agtgggagtg
     1921 acatttgtct taggtataac aaagtgtaaa atcaataaaa tttaaaagtc acatgaagca
     1981 agatatgatt gttatcttgg atttaggtag tcatgagaat acggtgttgg ctcgtgctat
     2041 tcgtgcgtta ggcgtttata gtgagattta tccgcatgac atcacggttg aggaattaaa
     2101 aaccttgcca aacgtgaaag gtatcattat caatggtggc ccaaacaatg ttatcgacgg
     2161 tgtagctatc gacgtgaatc cgggtattta cgagatgggc actcctgtaa tggccgcagg
     2221 tcacgataag gcgttgtgcg aggttaaatt gccggagttt acggatgatg tcgaggcgat
     2281 caagggcgct gtcaagtctt tcgtgttcga tacttgcaag gctgaggcaa actggaatat
     2341 gacgaatttt gtcaatgacc agattgaatt ggtaaagcgt caggtagggg ataagaaagt
     2401 tctgctggcc ttgtctggag gtgtcgatag ctctgtagta gccgctttgc ttttgaaagc
     2461 gatcggcgat aaattggttt gcgtgcatgt gaatcatggt ttgatgcgta agggcgagtc
     2521 cgaggatgtc gttgaggtct tcaagaacca gttgaatgct aatttggtgt atgtagacgc
     2581 taccgatcgt ttcttgaata agctagctga cgtggaagat ccggagcaaa agcgtaagat
     2641 tatcggtggt gagtttatcc gtgtatttga ggaagaagct cgcaaattag atggaatcga
     2701 tttcttggct caaggaacga tctatccgga tatcgtggag agtggaacga agacggctaa
     2761 gatggtgaaa tcccatcata acgtaggcgg tctgccggaa gatttgcaat ttgagttggt
     2821 tgagcctttg cgtcaattat tcaaggacga ggttcgtgct tgtggcgtag agttaggttt
     2881 gccttatgat atggtttatc gccagccgtt ccccggaccg ggtttgggcg tacgttgctt
     2941 gggcgctatc actcgtgata gactggaagc ggtacgtgag tcggatgcga tcttacggga
     3001 ggagttcaag aacgccggac tggataaaaa ggtatggcaa tactttacgg tagtacccga
     3061 ctttaagtcg gttggcgtac gtgataacgc ccgttctttc gaatggcccg tgattatccg
     3121 tgccgtcaat acggtagatg ccatgaccgc tacgatcgag ccggttgact ggcctatctt
     3181 gatgaagatt acggatcgta tcttgaaaga ggtgaagaac gtgaaccgtg tatgctacga
     3241 tatgtctccg aaaccgaatg cgacaattga gtgggagtaa ttaggcttac tttttaaaca
     3301 gatataaaaa ggcccggtga tttatcagaa tcccgggctt tttatttata tacgatagat
     3361 tcgaggaact attttagttc acggatcttg atattacgga accagatcgg ataaccatga
     3421 tcttgcagac cgatataacc ttctttagag ataccttcgg taaaacccgg gaagttcttg
     3481 aatttactgt tagctaccaa atcatcccat tctttgctcc ataaagtgta ctcaactact
     3541 tttttgccat tttgagtatg cgttaccttt ccatctttta cacggattac gatcgtattc
     3601 cactcgccgg caggattaac tgttttcgga tctgcgggaa gcatgtcata tagagaacct
     3661 gctaagtggt tcgctaattt gttgtcggtt gcgtccacgt tatctagcac ctgtacttcg
     3721 ggagccgcat aataaatagg tttgccgggt acctcgcgta cataatagaa gataccggag
     3781 ttgcccatct tgctggcttt ccagtctacc gaaagctcga agtttttgaa tttcttgttc
     3841 tggtaaagga tatcgccatt agcgccttgt cccggtttct taccttcgcc ggtaaatact
     3901 ttcatggcat tgtcttctat aacccagttc gcaggcatag cggtaccgtt acattggcgc
     3961 catccagaga agtcttttcc gttgaataat aattcccagc cagctttttt ttccttctta
     4021 gtcaatgtat tcggagtttg agcgaaacag gggatagcca tagctatggc cgaaagaatc
     4081 aagaatgatt tgaacaactt tttcatgtta cttaaattgt tattagatta gatttgttaa
     4141 tatcattaca aatgtagcaa tttgcttaat aacccttatg aggattaacg tatttttaat
     4201 ggaaatagga ttattctata ttagtgtcat cttcaatacc ctttagaaag tcggataaag
     4261 agatatttaa tgctctggtt attttaatta aggttccgat tttgatatct tgtttggctt
     4321 gttctaatat aaaaatattg acgtcggatc tgaacatcag ttcacgttgt gacatactac
     4381 gttccttgcg taaagatttt atcctttgca caatacgttg tattattatt ttgtcactct
     4441 cgtttatcat aaatagagta acaaagtatg tgaagatttt tatgtaaata gctatagtat
     4501 attatagcat aggtctgttt ttttcgtata tttgcggtgg ctattgatca aatatgctga
     4561 tctgcgttca tgtttttgtt gtattcatta aaattgataa ttgcaattgc aacgcatttg
     4621 cttgtttagt taaggtggtt ttcatttgtg acaagcagta aagacatcct gtcagtgatt
     4681 gatcggatgt ttttttgact gctggagagt gaagttttta taaaccatcc cgtacttctg
     4741 tctgtaaaca agattgaata tggggataga ttgacaaact gttaaaacga atccgaataa
     4801 cagacagggc atctgcgatc aataatcaag ttacgattac cctccggtaa tgtgaggcat
     4861 cttaccggac tctattgatt taacacatga atcgtatggc aagccactag cgcggccgtt
     4921 tccgtacgca gccggctctc tcctaaagag atcggctcga agccattctc ttgagccagt
     4981 ttgatttctt ccgggctaaa atcaccttcc ggtccgatga ggattaaggc attctctccc
     5041 ggctgatacg tatgttttaa tagtggcttc tcgccttcct cgcaatgggc gataaactta
     5101 cgcccgtcaa agggagtggc gacaaacttc ttgaaatctg tcattccttc taacgccggc
     5161 aaagtcgctt tctgggattg cttcatggca ctgaccaata tcttctccaa tcgaatcggc
     5221 ttgatctctt tacgctctga gaaacgacaa ttcaaacagg tgatcgcatt gatccctatt
     5281 tccgtcgctt tctccacgaa ccactccatc cggtccatgt ttttggtagg agctatggct
     5341 atatggagat tgaagttcca gagatcgggt tgtttccaac tctctaagag ggtcacctca
     5401 caatgtttgg gatgcgcccg gctaatagcc gctttataaa aagagccttg cccatccgtc
     5461 aatactatct catcgccttc acctaggcga agtacccgta tacaatgtcc tgcttcttct
     5521 tccggtaatt ccggcttgat agctatatct ggtgtataaa aaatctgcat gaccatctaa
     5581 ttttcaattc tgaattctca attttcaatt acccaaggat cataccaatt atagtagccg
     5641 atagcacaga gaccaaggct ccgccgatca tggccggtac gccgatacgt gaaattaatc
     5701 ctcgtttttc cggggctaat acgcccaatc cgcctaataa gataccgata gacgatatat
     5761 tagcgaatcc gcaaaggata taagtagaca tcaagatcga tttctcatac atgaataatc
     5821 cggcatcttt ccattgctgt aattggaaat aggcgacaaa ttcgttcaat atggtctttt
     5881 gtcccagtaa agatcctacc agcatgatat cctggcccgg tacacctatc aaccacatga
     5941 aaggagcggt gattacgccc agtatgaact ggaaagtcag tccttttgct ttgccgtccg
     6001 agatctgtac gatccagtcg ttcaatcccg tgtaacgccc gattacgtct tccgtaacat
     6061 aattcgctaa cgctactaac gagatgaata ccaataacat ggcagcgata ttcgtcatta
     6121 attttacgcc ggtaaccgta cctgatgaga tggcatctaa aatattcgag ttctcttttt
     6181 ccttgccgga gacagctaca tggtccgtgg cttcttccgt ctgcggacaa agcattttcg
     6241 ctaaaacgat tgaacccggt actgccatta cggaagccga gagcaagtga gtggcgaata
     6301 aaaccttcga cgccggatct gttcctccca acatacctat gtaagtaccc attacggaac
     6361 cggcgatcgt acccattccg gataccatga ccaaaaatat ttccgaacga ttcattgtcg
     6421 gcaggtaatt cttgatcaac acaggagatt ctgtcattcc cataaaaata ttaccggcgg
     6481 ccactaatcc ctccgagccg gatatattca tgaatttacg caatacccac gcaaaggcac
     6541 cgactacttt ctggataatc ccccaatggt aaaacatgga aaccaaggcg gagaagaaaa
     6601 taacaatcgg tagcgaatga agcaagaaac tgaatcctgc cgctttagag gcatacgggc
     6661 ctaataagaa agtaagaccg gcatccgtga agtccatcaa cttaacaaat atcttgccac
     6721 atccttccaa taggcttccg acgaacggca catataaaac cgccaaggcg aatacgatct
     6781 gcatgaacaa acctccacct actaatttcc aatcgatccg tttacggtca taactcatcg
     6841 cataggcgat acctaaaatc gtaatgatcc caagcagacc tcttaaaagt gagaccagtc
     6901 cgaatcctcc ttgttctcca atcatttgtt tgtgtcctcc tcttcttctc gacggcgcaa
     6961 ctcgtcttta tacattttcg cgtattcgta attttcgtcc gctatagcgt cttctaatcg
     7021 ctcgtttatt tcttggatat ccaataggct taaccatttc tttaactggg cttcgtcctt
     7081 aatctcatcc ggttctaatt ctaataaatt gtcatcctcc tctggttcgt cagcggggat
     7141 ggacagggtg tcttccagta cgacaccgca ttcctttaca atctcctcgg aagtaaagat
     7201 gtcgcatttt acccgaagcg ctatggcaat tgcgtcggaa gtgcgagagt ccagctttat
     7261 cgagcgctca ccgtcgctaa actctaattc tgagtaaaac acaccatctt cgaatttgta
     7321 tatgtaaact tccttaagaa tgacgttgaa ggcttgcgca aaagtggcga ataagtcgtg
     7381 tgttaatgga cgaggaggta cgatatgctc caaagcgatc gctatagact gtgcttcagc
     7441 ggttcctacg atgattggaa ttcgccgtgg accattttcc tctgccaaaa ttaacgcata
     7501 ggccccggat tgaatttggc tgttcgctaa tccttgaacc cttaatttta ttcttgtact
     7561 cacagatctg aaatttaaaa ttgtatacaa aagcaaaagt aatattattt tcgggattat
     7621 cgcgaataaa tgtgattaat cactttcagt gtgtttgggg ttaaggggaa ggataatgga
     7681 aaaacggctt ccttttccta tttcggactc tacggcgata tacccatcga aacgttcggc
     7741 tatcactttg caaatggata gtcccaagcc ggtacctttg gcgaattcat ccagtttcgt
     7801 gaaacgattg aaaacggcgt cttgcttttc tttcgggata ccaatgccgg tatcttctac
     7861 gaaaatatgt acatgccgct cttcctctcg gtattcataa ccaatcaata tatatccctt
     7921 ttgcgtgaat ttaatagcgt tgctaagaaa gttggtaatc acttgtgtca accgaaactt
     7981 atccgtggga atggatatgc ttttttccgg tatttgcata cgaagttcta cgttctccgg
     8041 cattaaaact tggaaagtct ggtaaatcgt gcttattaat tcatttagag aatattgctg
     8101 gaaagagaat gacatacggc ccgattcgat acgggaaaga tctaagatat cattgataag
     8161 gttcaataac agatcgctgt tcgtattgat taactcggta aagttttccc gttctgcctt
     8221 actgagctcg atgtctgtgt tcataagatt cgagaatccg acaatagcgt tcaatggagt
     8281 ccggtttatc gaatgttcgt ttcagtgttt cattaaaaat cgggtaggta tctttctttt
     8341 gctcaaaaga atggataagc acgattttct tttcttcttt ttcttggcaa cctagggtta
     8401 acaaagagac aagaaatatg gatatggcaa aaattaaata tttatgtgtg tgtttcatga
     8461 ttcttaatag atagatcttt tgcaaaggta gaagtttttt tgactatcaa agcaaaaaaa
     8521 aatggtcatc cgtcacggac aaccaatctt cattgctaac cttaaatcta ataccatgaa
     8581 aaacacggtg caaatatata gtattttatg ttgtacagca tgatttcgtg gcgtaaatcc
     8641 ttgatacgtt agctttattt taataatagt ccgtcctgct aaaggaccgt taacagttat
     8701 tgcttgcttt tcacgtactc atcggccttc tcttttaccc gatcggcacg tttttgagtc
     8761 tcgggatggc ttgagaacat ctgcataaac ttggacgatt tagcttccga ctcactcagt
     8821 tgtaacaatt tatttaatga gttagacatt ccgtacggat ctcgcccgta atctatacaa
     8881 aactggaaac cgaattcgtc cgcctcatac tcttgtttct gggaatattg agcgccagcc
     8941 aatgcctgtg ccatgtctcc cagttgagag tcggtcagtt tggatacggt tccacttacg
     9001 gctccggcgg cgtttttagc ggcggaggtc aagtaagcgt ttttcatggc gtctttagag
     9061 tcggaatgaa cgacgtgccc gatctcatga ccgataacgg cgaatacctc gtcatcgtcc
     9121 atgattttca tcaatccgcc acatacgcgt acacttccgt ctccacaggc gaaagcgttt
     9181 acatctacta cattatatac tttaaagttt aagtctaggc cggaaacttt ttttacattg
     9241 gcggtcaagc gttccaagcg ttgtcccatt tccgtatccg ggcccgctac ctcgttatga
     9301 gtgtccatcc attggatgta ctcttttgcc attttggcta catcctcgtc ggatagagta
     9361 gcggcatgcg ctacatcagt cgcggcatta atcacttttt tcgtattaat ggtcttgccg
     9421 ccaatcttga attgggcgga aactgttagg ctcactcctg ctaagaaagc caaggacaat
     9481 aagatttttt tcatgtttta aattagttag ttgtttgtga taaataattt tcgatctgtt
     9541 gaaaagtagc atctttcaac aatactttct tctctttgtt caataggtat aatgtgggta
     9601 tcgcttttaa gtcgtagatc tcgtcgtttt taagcgaaac acttttgtcg tatgggttga
     9661 tccaatcttt aggcatgacg gaaacgtgtt ctttccatgc gtccagatcc tcgtccggat
     9721 aaacggctaa gatctttagt ttgttgcttt ttgaaaattc attgatcaag aaggacgatt
     9781 ccatttgtct ggttatttct tgacaagcat ggcagtccgg attatagaaa aataataata
     9841 gataatccgc ttttatattg tataatttcc cggtttgtcc gttcgctaat gtgtacgtga
     9901 aatcggtcgc aggcgtcccg attctgtttt ttaatgcgag ctctagcaaa tgggcgggac
     9961 gtatcttttc cacatcgctt aatgacgagg attcggtaag atattccaat accgctatat
    10021 acatttcctc attccttaag ggggagttcg ggtcgtatag atatttctcc atcatctcgg
    10081 aaaagtactg aaacatggca ctgtcttgtt ctgtttgttt catcatcgct tttacggaag
    10141 aagacatagc cgcaggcgag acatagttca tcaaatctat atagttggat aatgcctgct
    10201 cggtcacttg aggttcatgg atataggtcg tatccttgaa gtcgaattta tcccaataat
    10261 gtttcactaa atattcggcc ctttccactg ggtccgtgat taaggtgggg accgagacca
    10321 tttcaaaggt gggtggcgct acattggatt cctccgtttt ttgattgcgt tgaccactgc
    10381 atgcgttgac ggtcaacgtc aacaataaaa catatagata tttcatattc attcatatat
    10441 ttatgtttca atccacaaat atatagtatt ttttttatct ttgttaaatt aaaacagcaa
    10501 aaggtagaat atcatggatt ttcgattaaa agtatttcat agcgtagctt gtaacttaag
    10561 cttcacgaaa gcgtcccggg agttgttcat tagtcaaccc gctattagta agcatatcca
    10621 tgagttggag gttcagtata agacgcctct ctttgaacga acaggtagcc agatccgttt
    10681 aactcgtgcg ggcgagttgt tgttttcgca tacccattcc ttattggctt cgtatcgtca
    10741 attggatttc gagatgaatc tgttgacaaa taattttctg ggggatttac atttaggtgc
    10801 cagtacgaca atatcccaat atgttcttcc gcccgtgctt gctttattca ttaagatgtt
    10861 tccggatata catgtatctg tattgaatgg gaatagccgg gatatagagt tggctttgcg
    10921 agatggaaaa ataacgttag gattggtgga aggaactacc cgtcaaaata cgatgcatta
    10981 tatacctttt atgaaggatg agttagtggt tgtcactcat gtagggtcta agttggctgc
    11041 ttatgacgaa ctgacgttgg aacaactttg tgctttgccc gtagtacttc gtgaaaacgg
    11101 ctccggtacg cttgaggtct tggagggggc tttagcaaaa caccagatca aactgtcgca
    11161 attgaacgta ttattgcagc taggtagtac ggagagtatc aaattattct tggaaaattc
    11221 cgatgctttg ggaattcttt ctattcgggc ggtgacacgt gagctgatgg ctggacgttt
    11281 gaaagtgata gatattgagg gctttaaggc cgaacggact ttctcctttg tggagccgca
    11341 gggacagaac agcggtatgg aagaaagttt catgcgtttt gccagtcaac attggcaata
    11401 actttaggtt attcgctata aaaacttgtg aagtaaggga tcggatgaaa atatgtactt
    11461 tcgcgaacga aatcaaataa tgatatgttg tactaaataa atcaataatt atgtttagcg
    11521 aaaaacgagg taacgtatta catggtgtct tgctgatagc ccttttctct tgttccgcat
    11581 tctatatcgc ggagttccag tttgttaaac aaatgtcatt cagtccgctg attgtcggta
    11641 ttattttagg tatgttatac gccaacagcc tgagaaacca tttgccggag acgtgggttc
    11701 cgggtatcct gttttgtact aagcaagtac ttcgtgcggg tatcgtacta tatgggttta
    11761 agctgacctt ccagagcgtg attgcgatcg gccttccggc aatcctgatc gatatggtga
    11821 tcgtggtgct taccatcttg atcggtgttt gggtgggacg attgatgaaa atggataaag
    11881 accttgcttt actgactgcc acgggtagcg ctatttgcgg ggctgctgcg gtattgggcg
    11941 ctgaaccggt cgtgaagtgc gaggctcata agacggcggt tgccgtatcg acagtcgtga
    12001 ttttcggtac gctttctatg tttatttatc cggtgatgta ccgtgcgggt attcttgatt
    12061 tagacccgga gcaaatggga ctttatacgg gtgcgacctt gcatgaggta gctcatgtgg
    12121 taggagccgg taacgctatg ggaaaggaaa tttcggatgc ggctattatc gtgaaaatga
    12181 ttcgtgtgat gatgttagct cctgtgctag tggtcatgag tttcatgttg gctcgaactg
    12241 ccgtgaattc cgtggttaac ggggggagga atggcggagg cgttgcccct tctcgtggta
    12301 agatcactat tccttggttt gcgtttggtt tcttggccgt gattggtttc aattcgctcg
    12361 acttgcttcc tcatgcggtt gtagatggga tcaatcaggt agatacattc atgctgacaa
    12421 tggccatgac tgctcttggt acggagacaa gtatcgagaa atttaagaaa gctggcgcta
    12481 agccctttgt tttggccact attttatatg tttggttact agctggtggt tatttgttgg
    12541 cgaaatatgt gcctcaactt gcataagatc gtattttcct ctatttttgt gatcttaaat
    12601 aggtcgttgt ggataagatg agtctcttat ccataccgtg aaatataaaa agatggcatc
    12661 aaagattaca aaaggtatcc ttatttcttg ttggatagta tacctcgcta tattaggggc
    12721 ggtggtaatg gtgtttatgg cgatagcgaa tggttcaatt ggttatatgc ctccggtgga
    12781 acaattggag aacccgattg ataaatatgc ttcccaagtt atctcctcgg acggaaaggc
    12841 gttgggagcc tatgcgcata gcaaagacaa tcgtatttac gtgaattatg aggatctttc
    12901 gccggatttg gtgaaagcct tgatcgctac cgaggatatc cggttcgccg aacatagcgg
    12961 tatcgatgcg cagggtttgt ttcgtgctat cgtgaagcgg ggtatcttga tgcaaaaaag
    13021 cggtggtggc ggtagtacca ttacccagca attagcgaag caattattct cgccgagtgc
    13081 cgataatatg atggaacgtc ttttccagaa accgatcgaa tgggtgatcg cggttcaatt
    13141 ggaacgttat tacacaaagg aagagattat aaatatgtat ctgaataagt ttgacttctt
    13201 gtacaatgcc gtgggaatcc aatccgcgtc tcgtgtgtat tttggaaaga cccctaaaac
    13261 cttgaagatc gaggaagccg ccacgttggt aggcatgtgc aagaaccctt cttatttcaa
    13321 tccggttcgc cataacaagc gtaccatcgg ccgtcgtaat actgttttgg agcagatgga
    13381 aaaggccggg tacataacca aggcggaatg tgattcgttg aaggctttac ccttggtcgt
    13441 acattttacc cgtatggacc ataaagacgg tttggctcct tacttccgtg aataccttcg
    13501 tctgacaatg accgcgaaga aaccggagcg taaggattac gcctcttggc aatctcagaa
    13561 attcagtgag gactcattat cttgggcgac gaatccatta tatggatggt gtaacaaaaa
    13621 taaaaaagcc gacggagaat actataatct ttatacggat ggcttgaaaa tctatacgag
    13681 tatcgattcc cgtatgcaga aatatgcgga agacgctgtc cgtgaacata tgagtaaaga
    13741 tcttcaaccg gctttcttcc gggaaaagaa gggacgtagc tatgctccgt tctcaagaga
    13801 cgtaagtgtc ggtcaagtag acacgatgtt gatgcgtgcg atgcaccaga cagatcgtta
    13861 ccgggcgatg aaaaagagtg gaatggctga ggccgatatg cgcaaggagt ttgagaagcc
    13921 tgtcgatatg cgtgtgttta gttgggatgg tccgatcgat acgatcatgt ctcctttgga
    13981 ttcgattcgt tatcataaga gtttcttgcg tacggcgttt atgtcgatgg accctcgcac
    14041 cgggcaggtc aaggcatatg taggtggtat tgactataat gacttccaat atgatatggt
    14101 gaatggcggt cgtcgtcaga tcggttctac catgaaaccg ttcctttatt cgttggcgat
    14161 gatcgagggg atcagccctt gcgaccagat gctacatgtg cagcagcagt tgatggacga
    14221 gaacggtcgt ttgtgggttc cccgtaacgc cagcgcgaag cgaatcggcg agatggttac
    14281 gatcaagtgg ggattacaga actcggataa ctgggtaacc gcttatctga tgagccagct
    14341 ctcaccttat acgtttgttc gtttgcttca ttctttcggc ttgaagaatc atatcgatcc
    14401 ggttatctcg gtctgtctgg gtactccgga tgtatcggtg ggtgagatgg tcggggccta
    14461 tacggtattt gccaacaagg gcatccgggt agaaccttta ttcgtgaccc gtatagaaga
    14521 ttcatatgga aatacaatcg cgaactttac cccacagatg agtgaggtgc tgacggaaga
    14581 tgcttcctat aagatgctac atatgttgaa aagcgtaatc gacggtggta ccggaggacg
    14641 tgtacgtttc cgctacggta tcaaggcgga gatgggtggt aagaccggaa cgacccagaa
    14701 taactccgac ggttggttca tgggatttac gcctagcttg gtttccggct gctgggtagg
    14761 cggcgaggac cgttccatcc atttcgaccg cttggcggaa gggcagggag cgagtatggc
    14821 gttaccgatt tacgcccttt atatgcaaaa ggtttataaa gataaaacgt taggctactc
    14881 ggaagacgag actttcgaga tccccgagaa atacgcaaac ccatgtagcg aaggtgggga
    14941 ggaagatagc cccacgaccc caccggatac gggaggcatc gataagatgt ttgagtgata
    15001 ataatcagac tattacagtt tttttaaatt ccccgtaagg aaaacttttg tttccctata
    15061 gcaaaacaaa agtttcttca gcaggaaact tttgtttctt ccaatagaaa ctgcagttat
    15121 ctttatggaa aacagaaagc gctactgatc ctttttccca aatcctttgt tatactaaga
    15181 attaatggtt agatttgtga ctgttaatct taataaagga ggagctatat ggaccgtagt
    15241 aaaatgattt ctcagttgga agacccgtct gaagtctttg attttcttgt gatcggagga
    15301 ggagctaccg gcataggtat cgctctggat gcttcgacaa gaggatatag agtcgcctta
    15361 ttcgaacaat cggactttac gaaaggaact tccagccgta gcacgaagtt ggtccatggc
    15421 ggtgtccgtt atttggcgca aggagatgtc tccttggttc tggaagcttt gcgcgaacga
    15481 ggcctgctac gccagaacgc tccccatttg gtaaaagatc aaaccttctt aatcccttgt
    15541 tatcgttggt gggaaggccc gttttatacg ataggcctga tcctgtatga tgtgatggcc
    15601 ggaaaattag gtctgggacg ttcggtttgt atcggtccga aacgggcgct ccgtaccatt
    15661 ccgatgcttc gtccgaaagg gatgaccgcc ggggtgcttt atcacgacgg ccagttcgat
    15721 gattcccgcc ttgcgattaa tatggtccgc agctctatcg acgctggcgc ttgtatcttg
    15781 aactatgcga aagtcatagg gcttctgaag gatggcgacc gcaaagtatc cggcgttacg
    15841 gttcgagatg aggagaccgg tacggtttat caagtaagat cccgttgcgt gatcaatgct
    15901 accggtgtct tcgccgatga gatcttgcaa atggacgagc cgggtaaacg cccgaccgtt
    15961 cgccccagcc aaggagtcca tttggtattg gattcctctt tcttgcaaag tgattgcgcc
    16021 attatgattc ctaagacatc ggatggacgt gtgttgttcg ccgtaccttg gcatgataaa
    16081 gtcgtggtag ggacaacgga taccttgatg gaatcgccgg aaaaggagcc ggtagcctta
    16141 gagaaagaaa tccaatttat actcgatacg gccgctaatt atttgacccg gccacccaag
    16201 cgaagcgatg tcttatccgt gtttgcgggg cttcgtccgc tcgccgctcc ccgtagcgaa
    16261 ggtaaaaaga caaaagagat atcacgtagc cataaattga tccgggagaa atccggcttg
    16321 atcaccatta tcggaggcaa atggacaacc taccggaaaa tggcccaaga taccctagac
    16381 ctagcgatac gttacatgca tattcctaca aaagattgta ttaccgagcg ttaccaaatc
    16441 catggtagcc ggaagaatcc ggatttctcc gatcctttat acgtatatgg tacggatgcc
    16501 gacgaaatcc gtaacttagt ggcctcttcc cccgctatgg cggagaagtt gcatccggac
    16561 tatgcctata cggtaggaga ggtaacttgg ctggtccgta atgagatgcc tcgtactttg
    16621 gaggatgtat tggcccgccg tttgcgtatc ttattcttag acgcacgggc ggcgatggcg
    16681 atggctccta aagtagcggg gattctggct acggaatggg gaaaggacga gacttggacc
    16741 tctgctcagg taaaggcgtt taatgaggtt gcctcgaatt atatactgaa ttgacaaatt
    16801 gataaacgat actaatatag aaggatatga attttcgaaa taaatatgtg ttggcgatcg
    16861 atcagggaac cactagctcc cgggctatcc tgtttaatca tcaaggaact attattacgt
    16921 tggctcagaa gccattccaa cagtatttcc cgaaaccggg ctgggtagag cacgacccga
    16981 atgagatttg gtacacccaa tcgtctgtca tcaaggaggc gatggcaaaa gcggatgtca
    17041 cggatagcca tatcgcctgt atcggaatcg ctaaccaacg ggagactacc atcatctggg
    17101 accgggagac tggctttccc gtatacaatg cgatcgtatg gcaggatcgc cgtacggcgg
    17161 attattgcga ggaacttaaa tcccaaggct gggcggaacg tatcctgcag aagaccgggt
    17221 tggtgatcga cgcttatttc tccgccacga agataaaatg gatattggat aacgtaaagg
    17281 gtatccggga gcgtgcggag cggggagaac tatgctttgg aacggtagat acttggctgg
    17341 tttggaaact tacccggggc gctcaattca ttacggatgt gacgaacgct tcccgtacca
    17401 tgcttttcaa tatccgtact ttgcaatggg accaagagtt attggacttg tttacaatac
    17461 ctgcctcgat gttaccgcaa gtgaaagcct gtagcgaggt ttactgcgag acatcaactc
    17521 ctatttttaa gaaaggcatt ccggtatccg gtatggccgg cgaccaacag gcggctctgt
    17581 tcggccagct ctgcgtagag gatggtatga tcaagacaac ctacggaacc ggctgcttta
    17641 tgatcctgaa taccggtaag gaacccgttc tttcccagaa taacctattg acaacgatcg
    17701 catggaaatt aggggatcag acgacctatg cgctggaagg tagtgtcttt gtgggaggtg
    17761 ccgtcgttca atggttgagg gatgggatcg gcttgattcc gaatgcctcg attacggagc
    17821 aaatggcgaa atccgtcagt gataatgggg gcgtttattt tgtgccggcg ttaacaggct
    17881 tgggtgcgcc gtattgggat caatacgcac gtggcgctat tatcgggatt acccgcggaa
    17941 ctacggcggc ccacttgacc cgtgcggctt tggagggcat ctgctatcaa gtatatgatg
    18001 tattgatggc catggaaaac gatattcacg ccaagccgaa agagattcgg gtagatggcg
    18061 gtgctatcgc taataacttc ttgatgcaat tccagtccga tatctgccgc tgtccggtcg
    18121 tacgtccgaa tgtattggag acgactgctt tgggagccgc ttatttggcg ggcttggcga
    18181 tcggctattg gaaggatatc gatgaactga aagaacaatg gtgcttggat aaggtcttta
    18241 acccacaaat gaaagaggat accgcccgta aattattgaa cgaatggcat aaggcggtgg
    18301 ggcgttctca gaattgggct gaataatgaa aatcatctta taggcagatt aacaagttaa
    18361 caaattctta aattattatc ttatgtctcc atttttagcg gaattattag ggactatgct
    18421 cttgatcctg atgggaggag gagttgtagc gaatgtctgt ttgtcgaaaa caaaaggcaa
    18481 tggagcgggc tggatagcga taacgaccgc ttgggcttta ggcatattta tcggtgttgt
    18541 ggtagccggc ccttatagtg gcgcacattt gaatccggcg gtatcgatcg gcttggcgat
    18601 cggagggact ttcccttggt gtgatgtatg tacttatata gccgggcaaa tgataggtgc
    18661 cgctttgggc gctttattgg tctggctggt ttataaggat cacttcaacg ctacggatga
    18721 tccggatgcg gaattaggcg tattctgtac gagtcctgct atcaaagatt atccaattaa
    18781 tttcttaggt gagatgatcg gtacgttcgc cttgatgttt gtcgtatttt ttataacgga
    18841 cggagaacta acctacgaaa gcaatagtac cttgccgata ggtttaggtt cggtaggtgc
    18901 cattccggta gcgtttacgg tctgggtaat cggcctttcc ttaggtggaa ctaccggtta
    18961 cgcgattaac cctgcccgtg atttagctcc ccggttcata cactttattt tgccgatcaa
    19021 gggaaaaggc agcagccatt gggagtatgc ttgggtacct gttttagggc cgatagctgg
    19081 ggccgctatt gccggtatgc tctattatgt attgaaataa tctcttgtat catccggatc
    19141 actttcggaa ccgccgcttt tacctcgggt gtcagatcca ttccgacctc gttgatattg
    19201 agggtggaga tgacaatgag atgggtttcc gggagatcgt cggtcaggat catggcgtcg
    19261 atcatatctt ttagaccgat ctcgtgggcg ctcatgagcg ggggaaagtc ggtggcgtaa
    19321 cgaggttgga tcagacggac ggtgcccgga aggttattat ccagcgtggc atcgatcatg
    19381 atgatacggt catatccttg cagccaactt aataaatgaa gccctcccgt gcccccgtcc
    19441 atcaaatgga cgtgagccgg gagcttctcg ttttctaaag ccttgataac gtgtatgcct
    19501 acaccttcgt ctttcagcaa taaattgcct actcctaata ctaatgtttc cttctccgct
    19561 ttcatccttt tttagcgatc ttagtgatag tctcggcagt ctcggttacc tcttctttgt
    19621 ccgctatgtc ttcctcgata aacttccagc caccgatgat ggacgaagtc tcgccacgtt
    19681 gctcgatata gtcatgataa aataccagat aaatatgaac gatagcgaaa aggatgaaga
    19741 accacatcag gaaatgatga atctggcgag ccatcaaatc cccgcccatc aagggaactg
    19801 tccatgcgaa cagttgcggg aagaaggact ggctcatctt cgcgtacagg ccgaatcctg
    19861 tgatactttg taacaaaaat gcccagaaag ttccgaaata aatcaagcta gccaaggcgt
    19921 tatgcccgat actgtctacc ggtttgttct taatcatcaa gatatctacc ttgatcacct
    19981 ccaatacctc tttccattgg gatttcttta aagggatgaa gttattccat ctggcataac
    20041 gattcccgac gaatccccaa taaagccgga atacgaaatt gaagaagaat acgaacgctg
    20101 ttacgaaatg gataaaccga accacgccga accaatagct gaaataagcc tccgaagcgg
    20161 acatgattgc gggaggatcg gcgatgataa agcctgtcac gcagagtatg acgatacaga
    20221 gcgcattcac ccaatgatag atacgtacgg gtaattccca tacatacact tctcttaaac
    20281 gtttcttacg aatcttcatg gctctattgt tttttagaat gtatcaactt ggtgcacata
    20341 ttttccttcc tcgtcataca gatgcacggc acaagccaga caaggatcga aagagtggat
    20401 cgtccgaaga atctctaggg gttgcttcgg atcgtatatc ggcgtaccga tcaaagcgga
    20461 ttcgtaggcg gacaatacgc cgttctcatc cctcggtgag gcgttccaag tagtaggcac
    20521 taccatctgg tagttcttta cccggttctt gtcgatcacg atgaaatggg ctaatgctcc
    20581 acggggagct tcggccaatc ctacgccttg ctcatgatcg ggccagttct cccgttccca
    20641 ttcggcactg tttgccatcc gggaatcccc gttctctagg ttcttgatca attggttgaa
    20701 aaactcaagg gcccagtctg ctgccattct acattccaat ccacgagcgg cggtacgtcc
    20761 tagggtagag aataaagcat ctaccggcaa gtcgagctga cgtaaagtct cgtctacgat
    20821 actcttttgg ggttccttcc ctgcggcgta agctacgatc aaacgggcta acggacccac
    20881 ttccattggt tcctgtttcc accgtggcgt cttgatccaa ctatatttat cctctacgtc
    20941 cagcaactta taggggggac gagggccggt atattccaga tgagtctctc cctcgtaggg
    21001 atgcaaaccg gctttgtctc cttgcgtgta tttataccat gaatgataaa tgtactcctt
    21061 gatttcctcc ggggagttag cgtctacggg atgtaccttg cttaggtcac gatccaaaac
    21121 gattcctctg gggatcttat aactttccac ttccccgaga tcgaacatcg gatagtctcc
    21181 gtaagacaaa tagtttcgta ctcctccgcc aatcttactc catttgtctt tataaacgtt
    21241 ggcgatcatc aataaatccg ggatataaac ttgattgatg aatgttttcg cctcctctag
    21301 tttctgcttt accagagcga gtcgatctgc gttgatcgca ttggcctcat ttaagtcgat
    21361 gctgcaaggc ataccgccta cgatatagtt tggatgcgga ttcttgcccc cgaacacggc
    21421 gtgtaccttg acgacctctt tctgccattc caatgcgtcc agataatgga cggtagcgat
    21481 aaggttctgt tccggcgtaa gtttatagtc cggatgtccc caatacccat tggcgaatat
    21541 accaagctgc ccgctggcaa cgaacttctt tagccgttgt tgtgtggcgg tgaaataccc
    21601 ctcggtattc tttgcccatg gagaaagttg ctgggcaagt aaagcggcgg ctttcggatc
    21661 ggcttttaag gcggatacca catctaccca atccaatgca tgcaattgat agaaatgcac
    21721 cgtatggtca tgcatataca atacggcttg catgatatta cgaaccatac tggcgttggg
    21781 agggatcacg ataccccgtg cgttctcgac cgcccgtacc gaggcaagcg agtggatgga
    21841 agtacatacg ccgcaaacac ggcctacgaa agcccataca tcccggggat cccggtcttt
    21901 tacgatattc tcgatgcccc gcaccatggt acccgagcta taggcgttct tgatagtgcc
    21961 accttctatt tcagcctcta cccgcaggtg gccttctata cgggtaatgg ggtctatgac
    22021 aattctttct gacatgatag tagtgtttta ttagatcgta gatttacttt ccggctcatc
    22081 attgtcgata agctcttttt tccgtatgtt agtcgctacg gcatgtacgg cgataccggc
    22141 ggcggtagcg gctcctagag ccagaccgat ctgatccgcc gtggcctcga taccaaatcc
    22201 gtgtatatcg ggcatacgtt tatagaacgg gctgttgtcc cagaaattct cctcgctgca
    22261 acctaaacag gggtgaccgc tttggattgg gtaactggtg ccctcgttcc atttgatgat
    22321 accgcacgag ttataggtgc ttggaccttt gcatcccact ttatacaggc agtagccatg
    22381 cttggcattc tcatcgtcga agctctccac gaacaaaccg gcgtcgaaat tcgcacggcg
    22441 gtagcacgta tcatgtaccc ggcgtgagta gaacatcttc ggacggccca atccatccaa
    22501 ttgtggcata cgatcgaagg tcaacatata gataatgaca cccgccatca cgtcggcgat
    22561 cggaggacag ccttgtacat taataatagg tttacctttg atgactttat ggataccttt
    22621 agcgccggta ggattcgggt tcgccgcttg cacgcaaccg gcggaagcgc agttgcccca
    22681 agcgatgatc gctttagctc ctgcggcggc ctcttcggtg atctgcaagg cactcttgcc
    22741 gcctacgcaa caataagcct cgtcttttgt aggtaacgat ccctcgatca tcagcagata
    22801 attgccgtaa tattttttca tggtctcttc cttagcggcc tcggcctgtt cgccggcggc
    22861 ggccatcagc gtctcggtat agtctaggga aatcttgtct aacaacaagg tagccacgat
    22921 cgggtgggcg gcacggataa acgattcggt acaacaggta cattcctgta ggtgtagcca
    22981 gatgatcgga aggcggggtt tcgtctccaa ggcatttact acctgtgcca ctcccgaagc
    23041 ctccaatccc atcagggcgg ccatggtggt acagaacttc aggaagtccc ggcgggagat
    23101 gcctttctga cggcactctt cgtaaacgga cggtctttta ttttccatat ctcagcaatt
    23161 aagtattcta acaaatacgg gggagttgct ccccgcttag catatcgatg atccggtagt
    23221 taccgtataa tgtcttcatc ttgacccggg cttgctctcc gctttgcttg gtgatacggc
    23281 cgataacggt cgcttgcctg ccctcctcaa aacatctcat aaggggtaac gcttgttccg
    23341 caaggctttc cggcaggatc acaagaacca atccttcgtt cgctatatag agcgggtcta
    23401 atcctagcat ctcggatgcg gcacgtaccg cttccggaat aggcagggcg tcttcgtcca
    23461 gcaggatatc cacaccagcg tcttgggcga tctcgttgag ggttccgctt acgccacctc
    23521 gggtggggtc acgtaagaca tgtacctctc ctatagtatg taacagctca gaaatcataa
    23581 tgtttagcga agcggtatca ctttttagat ccgtctcgaa tcccaagctt tcccgtgcgg
    23641 aaaggatcgt gataccatgt agaccaatcg ggccgctaca aatgacgaca tcgccgggag
    23701 tcgcttggtc tggggcgatt cgtatgcccg gagggacgat cccgatccca ctggtgttga
    23761 taaacaattt atcgcatttg ccccgttcca ccacttttgt gtctccggct acgatctgta
    23821 cgccggcacg ctccgccgca cgtttcatgg attgtacgat acgctgaaga tctgctagag
    23881 gcaagccctc ttccagtata aacccggcgg tcagatacaa aggacgggca ccacaacaag
    23941 ccaaatcgtt aacggtcccg ttgatcgcca gatcaccgat atctcctccg gggaaaaaga
    24001 tcgggtctac cacgaaggag tcggtagagt aggccagtcg cccttcttcc atagggaaca
    24061 cgcatccgtc atgatcctgc tccaataatg ggttccggaa agccggataa aatacttggc
    24121 tgatcagttg gtgtgtcatg cgtcctcccc ctccgtgcgc tagtaacaca cggtctgagt
    24181 cggtaaaagg aatcgggcaa ttcaagtgta tatccatatc tttctattta tatctataat
    24241 aagcggcaca aaccccttcc gaggagacca tcggggctcc cagcggatgg gtgggatggc
    24301 aggccttccc gaaatgggga cagtccgagg gttgtctcaa acctctcata atcagaccgg
    24361 cgatgcattc ggatgcgatc tggttttctt ccggacacaa ttgaaatctc attcgggagg
    24421 aatatctttt atattcggat cgaagttgaa gcccgctgga ggggatgatt ccgatgcccc
    24481 gccagtcttg gtcgcaaggt tccaacatct cgtctataag ttggcgggcg gcggcattcc
    24541 cttgctcggg aacggcccgt ttgtaagcgt tctctacctc ataacttccg gcttccaact
    24601 gggagacaca gcggtagata ccatataata gatctaccgg ctcgaatccg gtgacgacca
    24661 tcgggatttt atagtgggcg gctaatcggt gataggccct gttgcctgtg atggcgcaga
    24721 catgtccggc tgtcaggaag ccattcactt tgctttccgg atctgataag atagcctcga
    24781 tagcgggtgg taccgtgaat aaggaagtca atatggaaaa gttcggaagt cctcggcgta
    24841 tggcctcttt caaagccatg aggtggacag gtgcggtcgt ctcaaaacca atcgcgaaga
    24901 atacgatttc cttatccggg ttctcctcgg ccagtgatag ggcatccaag ggcgtatata
    24961 gcatacggat atccgctcct ctcgctttta cgctcaataa atcctcctta cttcccggaa
    25021 ctcgcatcat atccccgaaa gaggctaaga tcacattcgg ctgtgtcgcc aacttcaagg
    25081 cgtagtcgat tgtctcgacc ggtgttacac agaccgggca gcccggccca tggagcagtt
    25141 gaatatccgg cggcaacatc tcttccagcc gataacgggc gatagcatgt gtttgcccgc
    25201 cacaaatctc catgatatac caaggtcgtg tcaccttttt gcggatggcc tccagaagag
    25261 tttgtacctt ctcgttgctt ctatattcgt ctacgaaacg cacttttgta attctttaag
    25321 gtctttcagt gtttcctccg cttctttctc atctacaaca gatatagcga tccctgcgtg
    25381 agcgaggata taatccccct gtttcacatc cacccattca atacatatat tctttaggat
    25441 gcctccgaaa tcaactttag ccatggtcat ttcggggatg cttcgatcga ttgagataat
    25501 ctttccgggt accgctaaac acatatcgtt tcaatttatt taataacctc aaagatactt
    25561 aatatgttta agagggaaag ataaaattga taaatattat ttataagatg atggataata
    25621 tctctttagt aaatacgata gtcgattcgt gtctgattag acatttattc ctatatttgt
    25681 gctatggcga agaataaagt atatgcgttg attattcaag gcttggttca aggggttggt
    25741 tttcgccctt ttatctaccg gatcgctaaa gatctgggga tgaaaggttg tgtggagaat
    25801 atgaataatg gagtacgtat attggttgcc gctactccgg atgatcggga tttgctgata
    25861 agtcgtatac ggaccgagca tcctcgtgtc gcttatatcc atcggatctc ctatacatct
    25921 acggaaatgg atgaagatga ttttgacgat tttacgatta cgcctagcca ttcagaatcg
    25981 gatgaggtca cgcaggtctc cccggatatc gctgtttgtg cggattgtat gcgagaccgg
    26041 actactcaac cccatcgaat cggatatcct tttattaatt gtacgcattg tggccctcgc
    26101 ttctctatta tccgggacct tccttacgac cgttcgcaga caacgatggg cggtttcctt
    26161 atgtgtcccg attgtgagaa agaatatacg aatgttatcg atcgccgttt ccatgcccaa
    26221 ccggtcgctt gcaatcattg tggcccgact tattacgcga cttataacga ggagacttat
    26281 atcgattatg agaccttatt gaaacttacc tctcgcttat tgcttggtgg agaggttatt
    26341 gcggctaaag gaatcggagg ctatcatttg atttgtgatg cctcgaacga gagagcggtt
    26401 gcccgtctgc gagagataaa gcagcgggat accaaaccat tcgctgttat gttccgtgat
    26461 ttggaacatt tgcaggtcta tacggctacg gaaccgatgg aggagcgatg cctcgtctct
    26521 tggcgccgtc cgatcgtgct gctgaggcaa cggagccggt tagcttccgg aatcaatccg
    26581 ggcatgcata cgctaggatg tatgttgtct tatatgccga ttcattacga ttggtttgct
    26641 cgtacaggga tacctgcgtt ggtaatgacc agcgggaatc taagcgattt gccaatagcg
    26701 atcaccccgg aggatgcgga ggcgcaatta gcgggaaagg tagcggtcct cttgcatcat
    26761 aatcgcccga tccataaccg ggtagatgat tctgtgttgc aggtctgcgg aggacaaccc
    26821 tgcttgatcc gtcgttcccg aggctatgtg ccggaaccct ttttcacgga tacaaatgtg
    26881 gaagggatca tggctttcgg tgcggagaaa gtgaacacgt tcgctttggg aaaaggagag
    26941 acgatcctgc aaagtcaata tattggcgac ttaaagaact gggagacttt ccggttctat
    27001 acggaatcta tggagcggtt tcgtcatttg tttcgtttca atctccagcg attggtttgt
    27061 gatctgcatc cggattatct ttccagccaa gaggcggaac gtatctcgaa atctctttcc
    27121 ttacctttat taaaggtaca acatcatcat gctcatgccg ctgcttgtat gttggagcat
    27181 ggattgaatg agccggttct cgctatcgtg atggatggga caggtctggg tgatgatggt
    27241 aaggtttggg gaggcgagtt cttcttttgt gaccgagcga aataccgtcg cctttcccat
    27301 tttgagtatg tcccgttacc gggaggcgac aaggcggctg aggagccatg gcgaatggtt
    27361 gtcgcctatt tgtggcatta tttcaaggac gaaccgtcgg gtattcctta tccggccgat
    27421 ttcgtggaac gcataggcac ggaaaggatc gctatgcttg aacgaatgat ggagaaaggt
    27481 gtgaatacac cctatacatc cagcgctggc cggctgtttg atgcggtagc ttctttattg
    27541 gggatttgcg atgtctccag ccaccaagcg gaggctccgg tcttattgga gcaggcggcg
    27601 atgggagaga ggaacgctta tgcgtatcca gtctcggcgg agggagagga aatctctttt
    27661 tattctttgt ttgaggcatt attgcatgat aagacgaacg aggtcccggt gagcttgata
    27721 tccgcccgtt tccatacgac attggcttcc ttgtttgtgc agaaagcccg cttgttgatt
    27781 aaacggacga aagcgacaca agtggttatc tcgggaggat gtttccagaa taaattattg
    27841 acggagtcga tgaggagaca gttcatcatg gctggggtcc ccgtctatat tccgtctcgt
    27901 ataccttgta acgatggggg gatagccgtg gggcaattaa cgatcgcctc ggtgactccc
    27961 ttttaaaaga gatcagatat gcatgagttg tctatagccc gtagtatcgt ggagctggtc
    28021 gaggaacaag cggataaccg gggagcctcg gtggtcgaag agttggagtt agagatagga
    28081 catttgtccg gcgtagagat ccaaacctta gcgttcgcat tggatagcgc cataaaaggt
    28141 agcaagctgg aaaaggcccg gattatccgt cattatattg agggggaagg acagtgtagc
    28201 gactgtgaga ccattttccc aatgaacgcc ttgttttccc cttgtcccca ttgtggctcc
    28261 tatttagtta aaatccttaa agggaaggaa cttcggatga agtcgattgt tattaaaaag
    28321 gaatgatata ttaatgaaat aaaaacttaa atactatgtg cggaacttgc ggatgcggag
    28381 agcatcatca ccatcacgat catacgcatg agcattctca tggccatgaa catcatcacc
    28441 atcctgatga agggatcgta atcaatctgg aacaagatat acttcaacgt aacaacttat
    28501 tggcggagcg aaaccgggga tatttcgagg ctaagaacct gttctgcctg aacttgatga
    28561 gttcgcccgg atccggtaag acaactttgc tggaagagac gatccgccgt ttgaaagcga
    28621 agcgaccgat ctatgtgata gaaggcgatc aacaaacctc aaacgatgcc gaccgtatag
    28681 cggcgttgga gattgccgtg tttcaggtaa ataccggtac cggctgtcat ttggaagccg
    28741 acatggtcaa tcatgctgtt aagcatctga atccgaagga gggagcgata ctttttatag
    28801 agaatgtcgg caatctggtc tgtccggcca tgttcgatct cggagagtcc aagaaagtcg
    28861 ttatcgtgag tacgacggag ggagatgata aaccgttgaa atacccacat atctttcagg
    28921 aggcagatat ctgcgtaatc aacaagattg atctggctcc ttatctgaat acaaaggtgg
    28981 aagtgcttcg ggaaaacgcc ttgaaggtaa atcaccatct ccagatattc gaggtatccg
    29041 ccacgaaagg agacgggatg gatgcatggt gtgactggtt gcagacagag agtgcaaagt
    29101 gtaaataaat accccgggtt ttaatgaata aatggagaaa aaaactatat ttgctcccat
    29161 tcattgaatc taactaatca aaatgttatg attaaccgag aattgattaa tcctcaaagc
    29221 atcgtagtgg tgggaggttc caacaacgta cataaaccgg gcggtcgtat cgtgcgaaac
    29281 ctgttggatg gaaaatataa aggagaatta tgtgtggtaa acgccaagga gacagacgtg
    29341 caaggcgtca agtcttatcc ttctgtacat gatatcccgg agacggagtt ggcgatcatc
    29401 tcgattccga gtaaatcgtg ccccgaggtg atggaagtgc tggcccggca aaagggggta
    29461 aaagctttta tcgtgatctc agccggtttc ggcgaggaga cacacgaggg cggtatcttg
    29521 gagcaacaga tgctggatgt cgtgaatgag gcgggagcct ccttgatcgg cccgaactgt
    29581 atcgggttga tgaatataaa ttatcatggc gtgtttacgc aaccgatacc ggaattccat
    29641 cccgatggcg tggatttcat ctctagctcc ggcggtacgg ccttgttcat tatcgagtcg
    29701 gcgctgacaa aagggctgcg tttctcttct gtttggtcgg ttggaaactc caagcagaat
    29761 ggagtagagg atatccttga atatatggat cggaactttg atccggtatt ggattccaag
    29821 atcaagatgt tgtatatcga gcaaatcaag caaccggata aattgttgta tcatgcgtct
    29881 tccttgatac gtaagggatg caagatcgcc gctatcaagg cgggaagtac ggagtcggga
    29941 aagcgagctg cctcttcgca tacgggcgct atcgctagtt cggactctgc tgtggaggct
    30001 ttgttccgta aggcgggtat cgtgcgttgt tttagccgtg aggaattgac taccgtggcg
    30061 agtatcttta ccttgaaaga cgtgaaaggg aagaattgtg cgatcgtgac acatgccgga
    30121 gggcctgcgg taatgctggc ggacgcttta tccaaggggc gtttgaatgt tcctagtttg
    30181 gaaggcccta tcgctgatga gttgaaatcc aaactgtatc cgggtgccgc tgtcggtaat
    30241 ccgattgata ttatcggtac ggggacaccg gaacatttgg ctacagccat cgatttctgt
    30301 gagaatcgtt tcgataatgt ggatttgatg atggtcatct tcggtagtcc cggtttggta
    30361 aaactttatg atacctacga ggtacttcat aaaaagatgg aagagtgcaa gaagccgatc
    30421 ttcccgatat taccgtctat cgtaacggcc ggaccggaag tgaagagctt tgtcaagaaa
    30481 ggccatgtga acttctcgga cgaggtgaca ttgggtactg ccctttcacg ggtgatcaat
    30541 acgccgaaac cgatgagcac ggatatccag ctatatggcg tggatgtacc ggaagttcgt
    30601 cgtatcatag atcggttgcc gggtagcggt tatttaaatc cggaggaagt gcgtacattg
    30661 ttgcgtgccg ctaatatccc gttagtggag gaatatgctt cggatgatag ggatgcgttg
    30721 ctggcttttg ccaagaaggt gaaatatccg gtggtagcca aggttgtagg gcctgtgcat
    30781 aagagcgata tcggtggtgt ggccttgaat atccgtggag aagagcattt attgttcgag
    30841 tatgaacgta tgatgcgtct gccgggtgtt acgggcatca tggtacaacc gatgttgaaa
    30901 ggacaggaat tattcttggg agctaaatat gaggatcgtt tcggccatgt ggtactttgc
    30961 gggttgggtg gaatcttcgt ggaggtattg aaagatgtgt cttatggttt ggctccgttg
    31021 tcatacgatg agacttattc aatgattcgt tctttgagag ggtatccgat cattaaaggt
    31081 acacgtgggc aaaagggtat cgacgagcaa caatatgcgg acattatcgt tcgcctctct
    31141 accttattgc gttttgccag cgagataaag gaaatggata taaatccgtt ggtggctacg
    31201 gatagaggct tgttcgctgt agacgcccgt atccgtatag agaaataaaa aaacaagctc
    31261 ctttcactac tgaatgctaa tatacttagc agaggtgaaa ggagcttttc ttatttttta
    31321 gtcttcttct ttttcttatc gggaagatac tctttcagaa agcgtttgaa gctacttagc
    31381 gatacattgt atttctccgc tatctgggcg taagtcaagc tcgggtcttt caagtctttc
    31441 tcgatttgtt ccttataagg ctccaagcgt cccatttgtt gactaccttt cggacggccc
    31501 agcaccacac ctttacttct gatcaaggca agggcttcct tcgtacggat agagaccagc
    31561 tttcgctcga tctcggagac cagaccgaag gtaaaggcca aagtcttact gtcgatatta
    31621 tcctcgaaca catatccgtc gcttacgcta cgaagcgtta cctttcgctc tatacaaagc
    31681 aaaatgatat ggatgatctc gatcatctta cggctcacac gggatatatc ggacacaagt
    31741 atctcatccc cgggacttaa agatttgaca atactttcca gtctgcggtt cgcacgagga
    31801 ctatttccca cctctttagc ccacttcccg atctctatct tctgagattc ggcaaattcc
    31861 cggatcacag cttcttggac ctcggagttt tgcttattat tatatgttcg gataaaagca
    31921 attgtcataa tgtatatatt taattatctc cttttaataa cagatcgact tacgataagt
    31981 tcaaatatga caaatatatg aaacacttta attcggttgg cttaaaaaca aaaaaaccaa
    32041 ctaataaatt tattagttgg ctctttgcgg aagcgggggg attcgaaccc ccggtaccct
    32101 tacgagtacg tcagtttagc aaactggtgg tttcagccac tcacccacac ttccttgtgt
    32161 gttctgtgct tcttccttag aattgcgatg caaaggtaga actataattt taaataaaca
    32221 aggctttgca catcattttt ttcgaaaaaa gatactactt ttgtgcctta ttctgatatt
    32281 caatagatta ttcatggatt tgaacaaaca aattttatcg aggcgcccga taattatcgc
    32341 cttgatagcg attctcgttg ttttgatagg cggtggaggc ttttgggtgt accgtttggc
    32401 ttgggctccg aattttaagc cggataagac ggtctatgtc tatatagatg ataaaaagga
    32461 ttttgatgat ctttgccggc agttgaggga ttcggcgaac tgtctccgta tcggtagctt
    32521 taagcaattg agtggattgt tgaagtatcc tgcgtccatg cgtaccggtc gatacgccgt
    32581 gaagcccggc atgagtaatt taaccttatt gaatgatttg cggagaggac atcaagtagc
    32641 ggcccgggtt acttttaata atatccgttt caaggaagat ttggcggaac gtataagtga
    32701 tcaattgatg ttcgggaagg aaaatctcct gcgtctattg aatgattctg tgtattgcga
    32761 ctctttaggt tttaccccgg aaacgatcaa tgccctcttc attcctaata cctatgagat
    32821 ttattggaat atatccgcgg ataaatttat acgtcgcatg aagcgtgaat atgacgcttt
    32881 ctggacaccg gaacgattga aacaggcaga ggagatcggg cttactccag tcgaggtatc
    32941 tatcttggct tctatcgtag aagaggagac ggcggcatcg gacgaatatc caatcgtggc
    33001 gggcctttat atcaaccgcc ttcatgctgg tattccttta caggcagacc ctaccgtaaa
    33061 gttcgcggtg ggggattttt ctttgcgacg tatcttattt gagcatttgg aaatagattc
    33121 tccctataat acctataaat atgcgggcct acctcccggt cctctacgga ttcctactat
    33181 caagggcttg aatagcgtat tgaatcatac gaaacataaa tacttataca tgtgcgctaa
    33241 ggaggatttc tcgggacggc ataatttcgc cgtgacgttg gcggagcata accgcaatgc
    33301 caaccggtat cgggcggagt tgaataggcg ccggatacgg taatggatct agtataaatc
    33361 ataagtctct cattctaaat tgaacatttt tcattacctt tggcggctaa atagtgtgaa
    33421 tagtcaatat taagaaaaca gatacacatg gaaaaacatt tatttttggg ggacgaggcc
    33481 atagcgcaag ccgctataga cgctggaatc tccggggtat acgcataccc gggaacccct
    33541 tctactgaaa tcacagaata tatccaaggt tctccggtaa cgaaggaaag aggtatccat
    33601 tgtcgctgga gcgcgaatga gaaaaccgcc atggaagccg ctttgggtat gtgctatgcc
    33661 ggtaaacgtg cgctttgctg catgaagcac gtgggtttga atgtagccgc cgattgcttt
    33721 atgaacgccg ctatgagcgg tatcaacgga ggtatgatca tccttacggc cgacgaccca
    33781 tccatgcact cttcccagaa tgagcaagac aaccgtattt atggcaattt cgccatgatc
    33841 ccgatgtttg agccatccag ccagcaagag gcttatgata tggtatatca tggattcgag
    33901 ttatccgaga aattagggta tcctatcttg ctgcgtgtaa cgacccgtat ggcgcattct
    33961 cgtgccggtg tcgtaaccag cccgttgaag ccggagaacc ggatgaattg tccggaagac
    34021 ggtcgtcaac gttttatctt actcccggca ttggcccgta aacgtttcaa gagtttgctg
    34081 gcgtctcaag aggctttcac ggaagcttcc gagaattccg catataataa gtatttcgat
    34141 gccccgaata aagacttggg tatcatcacg acgggtatcg ctttcaatta tctttccgag
    34201 aattatccgg acggtttcga gcatcccgta ttgaagatct cccagtatcc gcttccgaga
    34261 aagcaagtgg agaagatcgt tggcgagtgt aaggagatct tggtgttgga agagggatat
    34321 ccggtcgttg aagagcaatt aaaaggtttc ttggcgaaag gcgtgacggt tcatggccgt
    34381 ctggacggta cgcttcagcg tgacggcgag cttacgccag acgcggtagg caaagccttg
    34441 ggtaaggaga tccagagcta ttacgcgatc cccgaggtgg ttgagcaacg tccgcccgcc
    34501 ttgtgccaag gttgtggaca ccgggatatg tatgaggcct tgaacgaggt gatcgccgag
    34561 tataacggta cggctaaggt gtttggcgat atcggctgtt ataccttggg agctttgcct
    34621 cctttccgtg cgatcgattc ttgtatcgat atgggcgcct ccatcacgat ggcgaagggc
    34681 gcttccgacg cgggtgtatt cccggctatc tccgtgatcg gcgattctac gtttacccat
    34741 tccggtatga ctggtttgct ggattgcgtg aacgagaaca cgaatatcac catcgttatc
    34801 tccgataatg agacaacggc catgaccgga gggcaggatt ccgccggaac aggacgtctg
    34861 gagtctatct gcgccggtat cggtgtggac ccggctcaca tccgtgtgat ggttccttta
    34921 aaaaagaact tcgaggagat gaagtctatc atccgtgagg aaatcgagta caagggcgta
    34981 tccgtattga tcccccgccg tgagtgtatc cagacattaa ccagaaagaa aaaagcaagc
    35041 aagaaatgaa aacagatatt atactatcag gtgtaggagg acagggtatc ctttctatcg
    35101 ccgccgttat tggagaagcc gccttaaaag aaggtctgta tatgaagcaa gcggaagtac
    35161 acggtatgag tcaacggggt ggagacgtgc agtctaacct gcgtctttcc gacgagccga
    35221 tcgcctcgga cttgatcccg aagggccacg ccgatttgat catctccttg gaaccgatgg
    35281 agagcttgcg ttatctgcct tacctgaaga aagagggttg gctggtgacg aactcccgtc
    35341 cgttcgtgaa catcccgaac tatccggaga tcgagaaagt gaacgccgag ttggacaagc
    35401 tccctcacaa ggtcgtattg gacgtggagg agatcgccaa ggaagcgggt tctgtccgtg
    35461 ccgccaatat cgtgatgttg ggggcagcta ccccatttat cgggatcgag tatgataaga
    35521 tcgaggcggg aatccgtcag atattcggtc gtaagggcga ggatatagtt aatatgaacc
    35581 taaaggcgtt gaaagccggt tatgacttag cgcaaagtct gcggtaaatc tttctccggg
    35641 tttgcatggt atcagcgtac gtgacatctc cgggtttcac gtacgttttt tttaacatct
    35701 aaccccctag aacttttaga agagctgtcg aggggtaggt acagcatcgt agaactttcg
    35761 taagccttag aattatgcgg tttgatgaga attttaatgt atctttgtcg ctgaatccta
    35821 aacgagaaat gattaaggtt atgaagaagt atttattggc tagtttacta gcgttattgg
    35881 ctttcgtagg caaagctcag gaggataatt ccgatatcgt gaaggtcggt gataccatgc
    35941 cgtcatttac gattgtttcc gacaacggga gtaagttgca gtccgcttcg ttaaagggaa
    36001 aagtgatcct cgtgaatttc ttcgccactt ggtgtcctcc ctgccaaaaa gaattggccg
    36061 ctgtccaaca aaccctctgg ccgaaataca agaacaacaa ggacttcgtt ctcttggtga
    36121 tcgggcgtga gcattccgat gccgatctac agaaatataa cgagaaaaaa ggcttcgatt
    36181 ttcctttgta tcccgataag gaccgggcta ttttcggcgc tttcgccaag aacttgatcc
    36241 ctcgtggcta tttggtcgga aaagacggga agatcattta tacgagcaaa ggctataccg
    36301 atgaggaatt tgctgagtta atgactaaaa tagagggtgc gttaaaataa gaatcatgaa
    36361 atatagtaac atacatttaa tttatttttc tccgacacac acgtccgcca agatcgttta
    36421 cgcgatagcg gaaggaatgg gtgccacttc gatgtccgag tctgatgtca cttgtgagag
    36481 tctggatatg gaagagtata ttgatgatga gctgacgatt atagccgctc ctgtatacgg
    36541 tggccgtgtg gcggagactg ccatggaacg ttttcgcatg ttccgttctg cccaccatgc
    36601 gccggtagtc cccgtggtac tgtatgggaa ccgggattat gaggatgcct tgaaagagct
    36661 ctgtgattta gtgtcggagc aggggttcgt acctgtggct gccggagcgt ttatcggcga
    36721 gcattctttc agccgcaagg ggatgcccat tgccgagggg cgtccggacg agtcggatct
    36781 taatcaggct acggaattcg ggaaaaagat tatcgaggag ctggagaagg tttcctgcgt
    36841 ggaatgcttg tccgccttgg aggtgaaagg taatttcccg tatcgggtga aaggcccttc
    36901 cactcctcaa gctcctgtta cggataacga tttatgtacg caatgtgagt attgcgtgga
    36961 tgtgtgtcct acgcatgcga tatccttggc agacgagggt atgtatagcg acccgaacca
    37021 atgtatcaaa tgttgcgcct gcgtgaaaga gtgtcccgag ggcgcacgta ctttcgatac
    37081 tccttacacg gcgatgctcc ataagaactt tagcgcgcgc agggagccgg agatattctt
    37141 ctaatggagg accgggcatc cggtatattg tgagggaaag cgtcaaaagg caaaagttct
    37201 tttggcgctt tctctttttt tgtacctttg ttcggatcgt taatctcaaa taataccgtg
    37261 tttgtatgaa aacctattta ttccttttgc tttttgtgtt tcaagccttc tccctttcct
    37321 cccagattag cctgaaaggg tataatcagg agaagatcga tccttctctt ttcgagggac
    37381 gatggaaagc ccgttggatc tcctacccgg gtgaggcccc gaatgtatat ggggtctatc
    37441 attttcgtaa atcgttcgat ctggaggtgg ttccttcccg gtttatcgtc catgtttccg
    37501 ccgataaccg gtataaatta tatgtaaacg ggaaattggt atccttgggc ccggcccgtg
    37561 gggatatcta taactggagt ttcgagacgg tggatctggc tccttatctg aagaaaggga
    37621 agaatacgct ggcctccgtt gtctggaatt atgccgagcg gaaacctgtc gcccagatca
    37681 gttacgatca gacgggtttt atcctgcaag gcaatacggg gcatgaggcg gtggtaaata
    37741 cggataccac ttgggtctgc ctgcgtaata aggcgtatgc tccttggacc gaatggcagg
    37801 tattggggta ttacgtggct ggcccgggcg aggaactgga agcctccgct tatccttggg
    37861 gctgggaaca accggattac gacgacagga aatgggagaa ggccgtacgg ggcatggagg
    37921 gtgccacgaa aggatcgaga gattacccgg gacggttgct ggttcctagc ccgatacctc
    37981 cgatggacag ccggatcgag cgtctggcca agctccgccg gtcggaaggg atcgaatgcc
    38041 cgcaaggatt tccttactgg ccaaaagctt tgacgatccc ggcgaatacg gaggtccgct
    38101 tgcttctgga taatgattac ctgacgacgg gttatttctc cttagccttc agcaaaggaa
    38161 aggaggccga gatccatatc ggttattcgg aagccctcta taagcaagaa gaggaatcga
    38221 ccactaaatc gtatgcgttg aatggcaagg gacatcggga cgagttgacg gataagcagt
    38281 ttatcgggta cggggataag atactggctg atgggggaga taatcgtctc ttcacctccc
    38341 tgtggtggcg tacatggaga tatgtggagt tgaaagtgaa gacggcttcc gagcctttgg
    38401 tgatcgagga tatgtatggg actttctctg cctatccttt ccgtaacgag accactttct
    38461 ccgctccggg acatgaggag ctgggccgta tgctcgagat aggatggcgt accgcccgtc
    38521 tgtgcgccaa tgagacgtat atggactgcc cgtattacga gcaactgcaa tatttcgggg
    38581 atacacgcat acaggcaatg atttccatgt ataatacatc agacccttat atggtgaaga
    38641 atgccataga gcaaggacgg cagtccatgg tggcggaagg gattacgatg agccgatatc
    38701 cgtctagcgt acatcagttt atatcctcgt tctctctctg gtggatttgt atggggcacg
    38761 attattggat gtaccgtggg gatgaggcat acatgaagac cttgcttccc gcttaccgtc
    38821 aggttttgtc gtggtacgag caatggttga agccggatta tagtttgtcg tacgttcctc
    38881 attggttctt cgtggattgg gcggccggtt ttgattatgg cgagccgata cgggagaaag
    38941 agggaaactc ggcgctccaa gatttgatgt atataatgac cttggagttt gcggtggaga
    39001 tggaacaagc gatcggcctc cctgccatgg cggatcatta ccggaagatc gctaccgaga
    39061 tgcgtaagac gatccgcccg aaatattggg acgctgcccg taatctattc gccgatacgc
    39121 aggatcatcg tggctattcc cagcatgtga acgccttggc gatcttgact ggggttacga
    39181 aaggagagga ggccgtaaag gtgatgaacc aaaccttggc ggatacgagc ttgatccagt
    39241 gtacgatcta tttccgttat tacttgaatc aagcgttgaa agcttccggt ttaggggatc
    39301 agttcttgga taacttacaa atatggcggg atcagatggc gttgggattg accacatggg
    39361 cagagatgcc ggagccatcc cgttctgatt gccatgcttg gggagccagt ccgaatatcg
    39421 agttttaccg gatcttgttg gggatagata gcgatgctcc cggatttagg aagatacgga
    39481 tcgctccgtc tttgggaaaa ctgaaggagg tttccggtac gatcccacat ccgcttggaa
    39541 gcgtgaccgc cgcttataaa ttggatgaga gaggtgaggg aaccgcccgt ctggtcttgc
    39601 cggaaggtac tacgggtata tttatctggg atggaaaaga aatcccgttg aaaccgggcg
    39661 aacaggttat ttcgttatct tcgcgtcatt aatctatcta aaatcctgat atgagacgag
    39721 tttattcaat tgccttattg ctgctggtcg ctctcggtct gtcggcgaca acgaaggaag
    39781 taaagttgaa attagtggaa accagtgata tccatggaaa cttcttcccg tataatttta
    39841 tcgagcagcg ggagtgggga ggaagtctgg cacgggtata ttcgttcgtg caagaagaac
    39901 gccgggcgta tggcgataac cttttgctat tggataatgg cgacatcttg caaggacaac
    39961 cttcggcgta ttattacaat ttcatggata cggtctctac gcatatagct tccgccatga
    40021 tgaattatat ggggtacaat gcgggaaata tgggtaacca tgatgtagag gctggccatg
    40081 ccgttttcga tcgttggatc aaacaatgtg atttccctat cttgggtgcc aatattatcc
    40141 gtacctccga ccgggagaac tatttaaagc cctatgaggt atttgagcgt gatggtgtga
    40201 agatcgttgt actggggatg attactccgg ccattcctgt atggttaccg gagactctgt
    40261 ggcaaggtct ttatttcgcc gatatggaag agacggcccg taaatggatg aagatcattc
    40321 aggagaagga gaaaccggat gttgtggtag gtatctttca tgcgggaaat gaggctcgta
    40381 ccatgtccgg ccagtaccgt gaggatgcgt cgatggaggt tgcccagcgc attccgggct
    40441 tcgatgtggt tatgatgggg catgatcatc gccggtattg tggtaaggtg gcgaatatcg
    40501 agggagattc cgtgttactg ataaatccgg caagtaatgg gcgtgtagtc ggttccgttg
    40561 atgtcgtgtt aaagatggag catggaaagg ttttggacaa acaagtatcg ggtgttttga
    40621 cggatgtgga taagttggag cctagcgagg agtttatgga gaaattcgct ccgcaataca
    40681 aagcggtgaa tgattttgtc tccgagaagg tgggaacttt tacggagagt atcgcgaccc
    40741 gtcccgctta ctttgggcca tccgctttta ttgattttat tcactcttta caattggagt
    40801 tgactggtgc ggacgtctct tttgccgccc cgttatcctt tgacgcaaaa atagataaag
    40861 gggatatcac gatcagcgat atgttcagtc tttacaaata tgagaatatg ctttatacga
    40921 tgaatttgac gggagccgag atcaaaggtt tcttggagaa atcatacgct atgtggacca
    40981 accggatgaa atctccggac gatcatgtct tattattgaa agagagaaag aaaggacagg
    41041 agaattatgt ctcattcgtc aacttcagtt ttaactttga ctccgcagct ggtatcattt
    41101 acaccgtgga tgtaacgaaa cccaagggcg agaagatcac gatcttgaaa atggcggatg
    41161 gtaagccttt cgacgagaat aaaacgtata aagtagctct taactcttac cgaggtaatg
    41221 gaggaggtga gttattgacg aaaggggccg gcattcccca agacgagtta aagagtcgta
    41281 tcattcattc gaccgataaa gacctccgtt attatatgat tcaatatata aaggaaaagg
    41341 gtgtacttag cccacaacct ttaaaccaat ggcaaatgat cccgcaggat tggacgagac
    41401 cggcggccga acgggattgt aagtttcttt tcggggaatg agtttccgtc cttgaagtgt
    41461 ctggtttgcg atagtatctc aatgggaaac ggtggtaaag tcaatggaat agagatggtt
    41521 tctcaatgac tttacggccg tgtcccattg acttttttgt atcccgtatt agggatgttg
    41581 ctgataggtt agggcgcaag gggcgcatct ttacgtatgt ttctaaaact ttttctgtaa
    41641 ataacgttta tacccctctt gtctgtagag tgatgtaaat attatttttc taaaaatgtt
    41701 tctttgaaag cgtaaagatg cgccttttgc gccctaggat ttttaccggg gaattttcct
    41761 gatgccttaa catgtggata tacagttgtt tgtgtggttc ttccctcttc ggctttttgg
    41821 gtctttgggg ggcgatataa tgggtcctta cccacgttta cgtgatccga aagcactaaa
    41881 accaagtgca tttcgcatga tttcatgagc taaaagccgt tttttctgtg tgatttccta
    41941 tcggggccaa gatcgttttt gtcgttttca tacgtgcaaa tgtactcgtg gagcacttgt
    42001 tttaagtgca cgtggtgaca catgaggcca cgtggtgggc catgtgagcc gagaatggat
    42061 atcgacgtat tattaacgta cgtgatcccc ctcgtgaaaa aaacttgaaa aataataccg
    42121 gaaaagtttg gaggttatgt tttataacac tacttttgca cccgcattcg agagagaacg
    42181 ccggtacaaa atgatgaaac aaacttttag aaaaaaagtt tcgaaataat ttggaggttt
    42241 gaaataaaag tccttatctt tgcagccacg ttcgcaaaac gaaagcgaca aaagagttct
    42301 ttgagagatt tacataattc aacaagtagt acaagtatag gagaagaaat tttc
//
LOCUS       DBMDTB010000025        41569 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_380_length_41569_cov_9.601862, whole genome shotgun sequence.
ACCESSION   DBMDTB010000025 DBMDTB010000000
VERSION     DBMDTB010000025.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 41569)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 41569)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41569
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_380_length_41569_cov_9.601862"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..737)
                     /locus_tag="ACZPB4_06125"
     CDS             complement(<1..737)
                     /locus_tag="ACZPB4_06125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010185466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HIR1097831.1"
                     /translation="MLKFFKTWTLPISMLAGAIGYFVFANVTFLEPTKPFMYTLIAYL
                     TPFLIFAQLLLTFCKISVRELMPSPWHGWLLLIQAVSSLVLAALLLWLPMREEYRDVF
                     EGAMVCLICPTATAAAVITGKLGGSASSLTTYTLLSNLLAAIVVPLVFPLVEPHAEIT
                     FFAAFLKILGKVFPLLLFPFFLALFLRRFIPPIHRFLAGLRDMAFYLWAVALAIVTGQ
                     TVKSLVNSEAEIYVEILIALGGLITCIA"
     gene            complement(807..1694)
                     /locus_tag="ACZPB4_06130"
     CDS             complement(807..1694)
                     /locus_tag="ACZPB4_06130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HIR1097832.1"
                     /translation="MSTQNNNIRYLNVSPMDELWGMMVTTVGYQSIPPHSIYPVRQQH
                     PLTYSFNPEKGRILTEYQLVYISEGCGFFESQSFKRKKIKAGTMILLFPGEWHTYSPA
                     ENGWYEYWVGFRGNLIEGWISNKFFSKENPVYEIGVNVTIIGLYEEIVSHAIKERNGY
                     QQLISSIVFYLMGEIYYKEKNRFLGQSDAVEKINEARAFMKRNIDNPMSVESIAQSLN
                     VSYSWFRSTFKSYTGVSPAQYQLHLRYLRAKELLSTSRLSISEIAYALNFETVSQFST
                     FFTKKEGLSPSKFRRQSQQ"
     gene            1974..3398
                     /locus_tag="ACZPB4_06135"
     CDS             1974..3398
                     /locus_tag="ACZPB4_06135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose isomerase"
                     /protein_id="HIR1097833.1"
                     /translation="MENKKINVGLVGMGLNTYWSQFEGLYERLCKYQKKIADSLTRPD
                     ISIINAGILDRPEEAKNIADVLSHENIEVLFVYISTYALSSTVLPLAQRLKVPIILLN
                     IQPSSHIDYTYINSLGDRGLMTGEWLANCQACSVPEFANILIRSDLPFKIVTGYLEDN
                     ATWTELNDWLDATVVMAGMREHRMGILGHYYCGMLDVYSDISQQSSSFGTHIELLEMC
                     ELKAYRDVASDLEIKKKIMEFQRKFEVVAECEETELIRAARTSVALDKLIKSHQLGSM
                     AYYYEGYPGNDYEDIVTSVIAGNTLLTGKNIPIAGECEVKNVQAMKILSLLKAGGSFS
                     EFYAMDFKDDVILLGHDGPAHFAMSDGKVKLVPLPVYHGKPGKGLSIQMTVKNGPVTL
                     LSVCEGKEGIFLLVAEGESVPGPVLEIGNTNSRYRFSCGVKSFMENWSKAGPSHHCAI
                     GIGHLASKLEKTGFLLNIPVIKIA"
     gene            3871..6939
                     /locus_tag="ACZPB4_06140"
     CDS             3871..6939
                     /locus_tag="ACZPB4_06140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008156093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SusC/RagA family TonB-linked outer membrane
                     protein"
                     /protein_id="HIR1097834.1"
                     /translation="MFPGIAGIAATESATLDNPLVSTVTQQNKKVSGVVYDTNGDPAI
                     GANVIVKGTTNGTITDMDGKYTLEVPANAILQISYIGYNTQEIPIGNKTTININLKED
                     TQALDEVVVVAYGTQKARSVTGSMSKLDASELSDMPVSQIGEKLQGKFSGVQINQANG
                     EPNGGLVIRVRGAASINGGNEPLVVIDGFPTTSGLASISPDEIENITVLKDAASASLY
                     GSRAANGVILVTTKSAKGVSAGKPHIDFSAYFGIDKVSNQGRPDLMNAQEFAQFKKEY
                     YEDQALYEGYTGGVPECYQNPQAIGKGTDWFDILLQDAITQNYNLGLSAAGEKFKSAV
                     NINYNAKEGIILNTYSNRFAARANNVYEASDRVSFGLNVSGSYTIGQLTDGLGGGRYI
                     IGSAMLMDPQLKYKNDDGTYPIAYTQPGMFANPNYYLVLTQRQNPSKTFRGTVNAYTD
                     IKIIDGLKYRLSANADLANNSRSNWIPSTANGAMFSAPPQPATGSYHTSNYVNWLLEN
                     TLTYNKTIANDHNLDILVGYTTQKNTQENARIDASDYPDDELPWFGAAITRTGNSDAD
                     KWGSWAMISYLGRLNYDYKEKYILSVAFRRDGCSRFGSNAKFANFPSVSVGWIASDEP
                     FMEKYDKVSHLKLRGSYGLVGNYNIGNYTYLASVGSYNYVTDGSITAGRALSRIGNNE
                     LTWETTKQMDFGVDLGLFNDRVFLVYDYYRKWTDGLLYQIDIPYSSGFSNIQSNIGEF
                     HFWGHEISLETKNMVGAFKWNTQINVSIDRNKAAKLGTNDTPIGGFNNQEDYNRTAVG
                     KPLGMFYGYVYDGVFMTEAEYEAGPKHASSMVGTVRMKDLNGDNKIDMDDRTYIGNPN
                     PDFTFGITNEFSWRNFDASLLLTGSVGNDIIDGTLEWTENIDGVFNVHKGVANRWRSV
                     DNPGDGQVPRTRTGTTELFRYTNSRWVSNGSYLRVKNLTVGYTIPIKKNPYVKGLRIY
                     ASGQNLLTWTGYKGMNPEVSGKGASGLYQGVDNTAYPVARTFSLGVNVKF"
     gene            6953..8512
                     /locus_tag="ACZPB4_06145"
     CDS             6953..8512
                     /locus_tag="ACZPB4_06145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RagB/SusD family nutrient uptake outer membrane
                     protein"
                     /protein_id="HIR1097835.1"
                     /translation="MKKRYLYVAALAALLNFSSCSNSFLDLNPDTAITANTFYKTAEH
                     FDQALVASYTAFRSIAQTGIMMDEMRSDNSFYTFYSGDRGPYASTEVLALFLDSGDPI
                     SWIETRYKDNYTCIGRVNTILNRLESSEMTDSEKNAVKAEALFLRAYYYYDLVQHWGG
                     VPLILEEVQNEADAFKAKSSAEEVYNQIITDLTEAITLGLPVPSKFPQSGRATMGAAK
                     MLRAYAYMSQPDRNYPAAEQDLKDITKMNYTLLSDYNAVFDKANKNNQESILEVQYAN
                     DGSTDEWNRIPWNIIPKCSNNEVLMGIAGSNYVGAWPGGTAGGWNVPTDEMIQSYEKG
                     DKRLEASIAVAEGTLDGDNFTFEEVKSPIGYTPAAGKDFRYFVKKYYHPPYTYSLRAD
                     DNFPVYRYSGALLLLSEALVKQGKNAEALPYINQVRERAGLKPLASVTLNDVMDEMRH
                     ELAFENKRWTDLIRNDQAIEKMTAFGKTMKALYPWILPSAFNVTKERFVYAFPRREMD
                     INYLLEQNPGY"
     gene            8606..9388
                     /locus_tag="ACZPB4_06150"
     CDS             8606..9388
                     /locus_tag="ACZPB4_06150"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097836.1"
                     /translation="MKTQELVKYLSFAITCGYLSWGLTSCDGQEAMSSDNWATLETGF
                     KDPKAEYRTAPFAVWNGKVTKEEVERTIQELKDAGSGGAFIHPRPGLITEYMSDEWYS
                     LYRHAVDYGKKNDMNIWIYDENSYPSGFAGGHVPELMPESYNQGQGLALKKVELLPEK
                     LDNCFICLKKEGDKWKDITNEIDSYKQKKGEYYLYEKTFYGRSDWYGGYSYVDVMVKG
                     VTEKFIDVTMQGYEKVAKNEFGKTIPGIFTDEPNIQSSGGLR"
     gene            9398..11719
                     /locus_tag="ACZPB4_06155"
     CDS             9398..11719
                     /locus_tag="ACZPB4_06155"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 2 protein"
                     /protein_id="HIR1097837.1"
                     /translation="MFDVFQQKWNYDLRPLLPLLEEEVGNWKEVRHNYMETLLQLFID
                     RWSKPFHSYCEQNNLQWTGHYWEHGWPYMNDGPDNMAMYAWHQVPAIDMLFNQFDDKS
                     PVAQFGNVRAVKELRSVANQMGYTRTLSETYGGGGWDETFKDFKRLGDWEYVLGVNFM
                     NQHLSHMTLTGARKYDYPPVFTYHSPWWSNYKSLNDYYARLSWVMSKGVQDNDILVIE
                     PNSTLWSYYSHTKSSKQLMEVGQAFQTFVTTLEKRQVEYDLGSENIIKDQGAIKNGQF
                     VIGKAAYSTVVLPPLMETLNKPTFELLQKFVQQGGKVVRFSSPNRIDGAENGELAKVL
                     SAQSVISYDQLNEKVIQDAFPPKDCKFSFKGGDLFHQRRKFADGELLFLVNSSMTESV
                     EGTIATVGKSAIRLDAMEGKIYSYPSVVDNGLLHTDFHLEPAGSLLLYYSNHILKGYP
                     EAPAIAGNTKLAASKSVEVKRLKENALNIDFCDVSVKGKTQKNIYFAQAADMVFKEYG
                     FTNGNPWNTSVQYKRNILDRDTFKTGGFVATYHFNVNDKFDYSTMKLVAERPEFFSVK
                     VNGQQVQAIPCEWWLDRSFGVYAIGNMVKQGTNTVEMSVTPMSIFAEIEPIYVIGDFA
                     VVPENKGWSISAPVEKLTLGSWKKQKQPFYSWDVSYTKEYDVKDTSKSYTIQLNAWNG
                     TVTEVYVNGEKAGIIGFDPYRLNIASYLKQGKNQVEVRVIGSHKNLLGPHYNNPNPGL
                     ASPWHWKNIRKQIPGSDYQMLDYGLMEDFDLVY"
     gene            11824..14742
                     /locus_tag="ACZPB4_06160"
     CDS             11824..14742
                     /locus_tag="ACZPB4_06160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HIR1097838.1"
                     /translation="MFKHSYKYALMVCLLLLSTSPIFSQKSDELRHSFNAPPNQAKPR
                     VYWWWLYNRINKEGITRDLQEFKEKGISGVNLICTGGYAGDKALEGIKWLSPEWRELF
                     RHAVSEAKRLDIELGFNLSGGWTMLGPWVTYDNAMKKVVQSDTIIAGGKKVSMKLAQP
                     ETVEGYYKDVWVQAFRIDTTKKLVDAESAKDLTLYMKPDGNFEWKAPKGNWLILRTGY
                     TLTGHTWSRWFAYPQGDTFAEGAGYEIDYLSKAALDNHFNHLGTIILDEVKKAGGNLA
                     YFWSDSWECGKLTWTQDFPEQFMHYRKYDLKPYMAILSGYIVKDSLFCERFQEDFDRT
                     IQDCIADNYYGHFYDLCHKNGLNVGNEAGGPNDIPPQDVLKNLGRCDIPAGEFWVHYK
                     LPEDGMNSRKSARLNLKQTASAAHIYGRREAQAEAFTQMEQDRTHWSLGPYDLKPYAN
                     DAFCEGINRFMLHQSTCQPPEDGKPGYEFCAGQHFTPNLTWWEQSSAFFSYLSRCQYL
                     LQEGKFVGDVCYYIGEQTPSLVPPHYIIPSLGLGYDCDYTNVEVLLTRMSVKDGRIVL
                     PDGMSYRLLYLQNCVSPDKEICEAVSRYQQLEVPTEASEMMSLDVLKKLRELIMDGAT
                     VIGAPPTMSAGLDNYPYADNEVRKLASEIWRDLDGKNITERKLGKGRIIWGKTAREVL
                     LADGIGQDFAYLNQTAEPEKFNYIHRSLDDCDIYFVINRTGKQTSSQFTFRVQGKQPE
                     IWDPVTGEMRIASSFTQHDGYTTVPLEFVPYGSYFVVFDKTISTDKQGEGDRNFSKLE
                     IAQDLSHSWEVMFDPTMGGPQKAFFEDLSNWIDRPEEGIKYYSGTATYRKSFDLSFPK
                     GNDGHIYLDLGNVKHVSSVRINNKDLGILWCTPWRVDITDYVKETGNLVEIDVINLWA
                     NRVIGDWKLPKEQRFTRTHDVFRFDMLRASTPLTDAGLLGPVSILKEKVWDMVTPITK
                     "
     gene            14749..17298
                     /locus_tag="ACZPB4_06165"
     CDS             14749..17298
                     /locus_tag="ACZPB4_06165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-rhamnosidase-related protein"
                     /protein_id="HIR1097839.1"
                     /translation="MKKILFFIIGIVFCLSSFATDTRSTALDLSPAKWIWYPAGRTLQ
                     NTFVLFRKDIILDKKPHKAIGWILADSRYRLFVNGKRIQWGPAPSDPRWQEADPIDLT
                     AFLTEGKNVIAVEVCFFGSGDGTHPMGKPGFILNLDMDQEKLVTDASWDCFLAKSWQP
                     GQYKRWFLRSLQEEFDARLYPYGWDTSDFKPDENWTKAILVSQDGKEPSVCNSSSEYV
                     WEIFGNKQLSEIRKRSIPAMREFDFHATTLEESMWIHWKRPVEDYFDLLVSDAFETID
                     KPITRSLGDGEWEISPQGNYAAALTFSFPEQGVGWPHFTIDAPEGTIVELLVHEAHQK
                     GGPALINSHFNSWSRFICKEGINHFETFDFESFRWLQLHIRNFNRPIKIASVGMRRRI
                     YPWKSDPTIVISDDTIQHVVNAAVNTLYNCAQETLVDGMARERQQYSGDGSHQLHAVI
                     QTLGDITLPYRFVNTFSQGLSIDGYFMDSWPAWDRLARTVERQMHLTGWGPILDHSIG
                     FCFDAFHYYMYTGDLQGLKEVYPRLLSFFSYLYKLTDKSEHLVPVENLGMCSVYIDHE
                     AYKQTKHKQLALNLYIVAMCQNALSTLCQAFGDTQKADEINQYAADILQGCIQKFWDK
                     EQQVYVNNLPWKDEEGEIRYCDRSLSTALIFDLCPNGETAKTLDLLEQSPAEMGVSYP
                     CNAVWPLWALAKYRKINTVLSDLREKWGNMSSVWANNTLQEFWKAYPDEGSQWSHCAM
                     YPLIALNQGIAGVYPLKPGCERIKMEPQLGDLEHIRFDVQTLKGAIQLSAQGIKGKRE
                     LRLQVPDSLSIELRLDKREKVDLPLLRTEKDGINVYEITHPGSYVLKLKYT"
     gene            17384..19999
                     /locus_tag="ACZPB4_06170"
     CDS             17384..19999
                     /locus_tag="ACZPB4_06170"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 78 protein"
                     /protein_id="HIR1097840.1"
                     /translation="MSLLKLSAQNENSCVPTNLRCEHLERPLGIDRQSPRFSWNLSDT
                     RNGAKQTAYQIAVGKDSLALSKGKGTIWKKKISGDQMLTTYTGKALEPCTRYYWSISV
                     WDKDKKKSQSVISSFETGLLTQRNWQGKFISDGKDMESRDTPYFRKQISLNKEVESAR
                     TYIVAAGLYELSINGEKVGDHYLDPAFTDYGKRLLYVTHDVTNLLRQGKNAIGVILGN
                     GWYNHQPVAEWNFHNAPWRDRPSFCMDIRIRYTDGTEEIIASDNSFKTNSGPITFNAI
                     YLAENHDFRKDMPNWNKPSFDDSSWQTATEVEKPDVIISSQTMHPIRITDFRKPIEVK
                     KLSDTLYLYNFGQNWSGITTFTVQGEAGTKVKLRHGEQLDSRGKRLFDDNNTQFYQNV
                     NEPLKYGKHPEDELFQTDVLILDGKKNTFTPHFNYKGFQYVEVSSDKPLEQDKQDMTS
                     HFIHTDLPQIGTFECSDSLINRLWRATNYSYLSNLVGYPTDCPHREKNGWTGDAHLAI
                     ETALFNYDGITLYEKWLADHRDNMYENGRLHCIIPSGGWGSDIVDWTCSVTLIPWAIY
                     EFYGDQTCLRDNYTEMKRHTDYWLSKFPEGLVGDAGLGDWVPHKAVANRELSASIYHY
                     KNADIMSRTAKLFGYEEEYKYYKNEAEKIKAAINNKYLNKETGIYASGYQTEQSMPLY
                     WGIVPEELKAKVEERLSERVHMNKDHLDFGIMGCKTVLNALTESGHVEQAFRIVTQQD
                     YPSWGNWLRQGATTLFENWDYNGLAWGYSQNHIMYGEIGAWFYKALAGINLDPQQPGF
                     KNILLKPHFVKELTYVKASYHSPYGEIISAWKRVGDKVIYQVTIPANTTATLYLEHKD
                     VPKTLSSGSYEFKIK"
     gene            20007..22676
                     /locus_tag="ACZPB4_06175"
     CDS             20007..22676
                     /locus_tag="ACZPB4_06175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HIR1097841.1"
                     /translation="MRILNKTILSGMLLLQMFAICTQASSLKVNHLKCEELVNPLAID
                     NTTPHFSWQLNSGWQGEQQTAYQVLVASDRERLNENKADLWNSGKVTSSASTWIPYQG
                     KLLAAKSFAYWKVRIWNKDGEVSEWSTPASFGIGLLSPQDWKAQYIGINNEDPQSPLL
                     RKTFEWNKKGDKMLLHVNSLGYHEVYLNGSPVSDVVLTPAVSQFNRRSLSVTYDITNS
                     LRIGKNELVIWLGKGWYQDQLPGVVKGGPFVRAQLEVRNNNVWETFQATDASWLARES
                     GYTSFGTWRPHQFGGEEIHAKKLIALDAVSLNKVNWAPVKVADIPEHTTSPQMVEPNR
                     IQLEFHPLSIEASGDTAWIFDMGTNLTGWTKIKFPPLEKGQRVRISYCDFLDKQQFRD
                     NLYEDYYIAAGKEQEFFINKFNYKAYRYLKVSNLKQAPALNDVTAYLIHTDYSSSSSF
                     ACSDEDLNAIHDMIQYTLRCLTLGGYMVDCPQIERLGYGGDGNASTPTVQTMFNLVPL
                     YTNWMQAWVDCMRTNGSMPHTAPNPYAAGGGPFWCGFMIAGSWQTYVNYGDARLLERY
                     YPFMQQWLEYVKEYTVDGLLKTWPNTDYRNWYLGDWATPEGIDQTDPRSVDLVNNCFV
                     AVCYQTMAKIAQTLGKPNDQKLYESKTEQLRTLIHKTFYDSKEASYGTGTQIELVYPM
                     LAGVTPESQLSNLLNTLYKNTAERFRGHLATGLVGIPIITEWCIKNQQVNFMHQMLKK
                     RDYPSYLYMIDNGATTTWEHWNGERSHIHNCYNGIGTWFYQALAGIMPDEAHPGYKHV
                     RISPQLAKGISWVKASKETPYGKILVHWEKKESSLLLNVTIPANSEATITLPSQTRQV
                     RLNGKTLTNATSIHIPSGNHQIVSSLPTNPEIE"
     gene            complement(22767..25334)
                     /locus_tag="ACZPB4_06180"
     CDS             complement(22767..25334)
                     /locus_tag="ACZPB4_06180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004559 - alpha-mannosidase activity
                     [Evidence IEA];
                     GO_process: GO:0006013 - mannose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 38 C-terminal
                     domain-containing protein"
                     /protein_id="HIR1097842.1"
                     /translation="MKKKLAIFVLSQFLLAGWADAQQAYFIDGYHGGIYGHYPVGQTA
                     FIAQKLRQNPNWNINIEIEPESWEVVRQRDPEGYEAFKRLFKDQSVESGRIEYVNPTY
                     AQSYFFGTSGESAIRQFEYGMRLIRKHFPEAVFTTYSAEEPCFTSCLPYILKSFGFSY
                     ASTKNPNTMWGGYVSAYGGELVNWVGPDGTRLTTVPRYACEDLQPGSCWQSISWFNTE
                     DYIHKCLDAGIQHPVGMCIQDASWSHGWDKGPWLGQDTTGYYTPTAYKTWRNYIQDCS
                     VGTTQDDWYFSQEDVLGGLMWGTQVMQRLAGEVRVAENAIVRAEKMAAYARLYKGMEW
                     PTERINEGWRTLLLSQHHDCWIVPYNQLQGKKTWAETVTDWTGVTNQNSRQIIDNALS
                     LLKEKEGESTVYVYNTLATDRNELVAVEVPVSWRNSDWVVLDKQGKKQPAQWLTEDGI
                     SKLLFRAQVPSAGYASYAIRKAEDKQSGTLKAERQKDGTFRMESDLYTLVLNPSKGGV
                     IESLKAKAVRGKEFVDNRNERGFNELRGYFIDEGGFLSSMDQPAEVSVLEQGPLFVKV
                     AVKGKIGKYSFTQTIRLTQGEPRIDMNVKLDWTGNPRIGEPGIEFRADNPRKAFYDDR
                     YKLLVYLPTQIANQQIYKDAPFDVCESRLENTFFNRWDSIKHNIILNWVDVASKDNSC
                     GLSLFTDHTTSYAHGKDFPLALNVQYAGKGLWGRDYIIDRPTEISYALIPHAGTWEKS
                     RIWTQSERRNEPLVATLGGDATLTSGSLFRIENNAYELVSMVYKGNDLYIRLFNAQSD
                     ASPKTITFQGQDVKASLVELDNRLVEDLTVTEKKGASSMRLSIPRYGIRTLKVSCKK"
     gene            complement(25403..26788)
                     /locus_tag="ACZPB4_06185"
     CDS             complement(25403..26788)
                     /locus_tag="ACZPB4_06185"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HIR1097843.1"
                     /translation="MKRYVLFVCLLLSGLARVYAQSIAPFQKGDRIAFVGNSITCGGH
                     YHSYIWLYYMTRFPDQRIDIFNEGVGGDVAEMIYQRLDKVFEHEPTVVTLSFGMNDVG
                     YMDFRKPGADTIARNRVEKACRDYALIEEVYKKYPEVRKILIGSSPYDETSRFNKVAF
                     PGKNTQILKIVDFLNARARENQWGFVDFNRPMVAINQWEQAADSMYTLCGKDRIHPST
                     DGHLVMAYLFLKAQGLAGKLVADIRIDGAGKKVTRSDNCRVSDLSVSSDNLTFTYEAK
                     SLPYPIDTSYYDNEKHTQADALSVIPFMDEMNYEGLSVSGLSDGYYGLTIGGEFIGRF
                     TARELERGINMALLQNTPQYKQAMKIRQMNEERWLKERKMREFYWVEYNLMRKTGMLW
                     ACNEAAVDTLRKYRPHDIFLQWNGDLWLQYMHKGIREDCVNEQQDLVNQIYEQNKPIP
                     LRIEIKKFTDL"
     gene            complement(26952..28466)
                     /locus_tag="ACZPB4_06190"
     CDS             complement(26952..28466)
                     /locus_tag="ACZPB4_06190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RagB/SusD family nutrient uptake outer membrane
                     protein"
                     /protein_id="HIR1097844.1"
                     /translation="MKNKAHVWMCGLLSATMAFTSCTNFLEEDPKTFLSPSEYYTTEN
                     QIKAAVDGTYDGLDDLLSSDLEIATVHLFNLEYLVGTSYRPRAAGNEQNQFLLLSGLE
                     ESNGIIRNFWKATFFPLENCNSVIQNVSATDIISESQKAKYLGEAYFLRAYYYFQGVQ
                     LFGDIPLKTEPTVDLNTVKIPRSPKEDIYNQIVEDLKKAEQSGLDWSDKTGHVSMGAI
                     KTLLAKVYLTMAGYPLQKGNEYYQLAYEKAKEVIDSGAFSLFADYKDLRALENENSGE
                     HIFMIQREAQDAGAPFHFGLLPYPEQPISITPAYGGGLAPRKEFYESYDDQDIRKRNE
                     EFFYTSKPKYGDPETTITLDVPYLCKYWDENAESTGKSGANIPVYRYADVLLMCAEAK
                     ATLDGGSTSDATAVDAYFQVRHRALPDEARPTSITVDQVLKERAWELCYEFTGWYDML
                     RTHRAFDPVSKQMVDLFGYQAVNHTYPFKESDLVFPVPLREKELNPLLGEDVVR"
     gene            complement(28500..31760)
                     /locus_tag="ACZPB4_06195"
     CDS             complement(28500..31760)
                     /locus_tag="ACZPB4_06195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HIR1097845.1"
                     /translation="MKITLLFLILGILHVSADTYAQKAQVTVEVKNGTFYDVVSEIEK
                     QTEFMFFYKSEDIDNSKQVDIQVKNRQVTDVLNELLKNTNLTYRISGKHITILKKDAV
                     QQQKKKISGIVTDPDGIPVIGANVVIKGTTVGTVTDLDGKFSLDAANNDILSFSYIGY
                     AEQEIEVGNRTLFNVKLAEDYKALEEVVVVGYGTMLKRNLSTSVGSVDSEKLLERPNA
                     TNVFQGLAGKVAGVNIALNSGAPGGSPAIKIRGIGSLNSSNTPLYVVDGVVGVDPDQI
                     DPNIVQSIDILKDATSSSIYGARGANGVVVITTKEGKKNTTNISYNTVLSAGTLARKV
                     DVLNAEEALDVFKRAYEAQPGRIAPHLDPSNMFTHKNDLFNPDGTPKYDTDWQDAVTR
                     TAFSHQHSLSFSGGSDKLTAVANVSYKDNQGIMLETYKRQLNAFINVGWDLKEWFHLQ
                     AMLNVGSSNARNSENAISRYTLEALPFLPVQYEDGTYSRKGDYPGAEDTENPVRILKE
                     RKNIDKNQYTLANVIGTFKITSWLKLTTSFSRQDGSYINSSYNPSTLFGYGDTQKGKA
                     EKAHRNTMSWTNEDYLTFDKSWNKHNLNVVAGASWYYSKTEKSELGAENFFDDYFEYN
                     NMGVGTVRSKVGSDYTDNKMNSYYARINYNFDNRYLLGASFREDGSSRFGLNNQYGFF
                     PSFSAAWRVSNENFFENAKKVIDDMKVRLSYGTVGNAEIGDYASMARYENKRLPFGKD
                     MTTIVTLKSMANPDLRWEKSRQLDAGIDLSFFNGRIEFMADYYHKITTDLLYELQLPS
                     NSGYEKTMTNLGKIRNQGLEMSLNTRNIQSRDFLWTTSWNYTMNRSMVLDINDNIIGK
                     WGGRIEEGHPLNALYGYVRLGTWGTDEAEEAAKYNKKPGDIKYWDKNGNGMKDGEDQD
                     YIGNGAPKFEMNMTNTFSWKGFTFMFDLQWVYGNKLINFTRQLMGNRVTFSNAYADIP
                     VNAWTPENQNTMVPSLRLPGDGYENDVDSWSCEPGSFLRLRNIGLKYDFSSRMLSAAH
                     IKSLSLGFNVENAFLITNYSGSDPEVTSYDAVFEQGVDFYTYPKPRTYSFTLGVNF"
     gene            complement(32005..33045)
                     /locus_tag="ACZPB4_06200"
     CDS             complement(32005..33045)
                     /locus_tag="ACZPB4_06200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecR family protein"
                     /protein_id="HIR1097846.1"
                     /translation="MESNNSIEELIIRYLQNEIQEDELRVLDAWIHESDANKAHFFEL
                     KGLFDTRKEVAFLNHYSVERSWERMAGKLDAISGVSVKSKVLGKQFWLSFLRYAAIIV
                     IAMGIGVGMNQWISNRLYAGDMEYNEIVVEKGGRANTLLLSDGSKIILNASTRFKYPT
                     SFNGDERVVHLEGEAYFEVAKNHSKPFIVKLKNQQITVLGTSFNIQAFNDDRFSVTTL
                     LSGSILLESFDAQGRKMSSMKLKPNQQARSDNRTGSIFLSETDASISNAWVGGKYRFK
                     DETLVSIVKRLENYYGVNIRLAHDSLRNIRYTGTFSLDQGIQEVLDIINSEKQFTFTK
                     DGKDILISARSK"
     gene            complement(33111..33677)
                     /locus_tag="ACZPB4_06205"
     CDS             complement(33111..33677)
                     /locus_tag="ACZPB4_06205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma-70 factor"
                     /protein_id="HIR1097847.1"
                     /translation="MSTLSMKDYIIKNHELDKFKLLYLENAPRLIFYASKYVDSDTAE
                     DLVHDIFIKIWQKKEIYSVEEGLKTYLFRSVQNACLDYLKHKSIEMTYADEVARRLKI
                     EEIDYYNQSDAAELEKERLDSVYREIAKLPDRCREVFTLAYVDGKKSVEIAGMLNISQ
                     RTVEAQLYKGLKIIRNVLALLALVLFFR"
     gene            complement(33836..35821)
                     /locus_tag="ACZPB4_06210"
     CDS             complement(33836..35821)
                     /locus_tag="ACZPB4_06210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HIR1097848.1"
                     /translation="MKTNLSSQITLTHIPLRYYRPENAFEHSVLTRLEKIPTNIYESA
                     EEGSFAIAKEIATQIRKKQDIGKPFVIALPGGRSPLSVYKELIRMHKEEKLSFRNVIA
                     FVEYEFYPLANPSAGNLARLKEELFDQVDIDPANIYCPDGSMPKDAILDFCRQYEETI
                     QSVGGIDCMLLGIGNSSNIMFNVGGTTISSRTRMVLLEGASRKEAARTFPSQENVPAG
                     IITMGISTMMNARSVILMAWGEDKASIVAKTVEGKVSDAVPSSYLQNHPNAKVVIDLS
                     AAYDLTRISHPWLVTSCEWDNKLIRRAIVWLCQLTDKPILKLTNKDYSEHGLGELLAL
                     YGSAYNVNIKIFNDIQHTITGWPGGKPNADDSNRPERANPYPKKVIVFSPHPDDDVIS
                     MGGTLRRLCDQHHDVHVAYETSGNIAVGDEEVIRYCEYLRDVCEKYSPDSAVKDKANE
                     IINYLRYEKVENGEPERKDVLFMKGTIRREEARHGCRYSGVKDDHVHFLDLPFYETGL
                     VKKNDLSEVDKDIVKALLLEIKPDQMFVAGDLADPHGTHKVCLDAVLAAIDEVKDEEW
                     MKNCRVWMYRGAWAEWEMDHIEMAVPISPEELRFKRNAILKHQSQAESAPYLGDDERL
                     FWQRAEDRNRATAELYRQLGLASYEAIEAFVQYIPLR"
     gene            complement(36004..37170)
                     /gene="nagA"
                     /locus_tag="ACZPB4_06215"
     CDS             complement(36004..37170)
                     /gene="nagA"
                     /locus_tag="ACZPB4_06215"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HIR1097849.1"
                     /translation="MLTQIINGHILTPQGWMKDGSVLISDGKILEVTNSDLAVIGAKV
                     VDAKGMSIVPGFVAMNIHGGGGFDFSECTEEAFHGAVAAHQKHGATTIFPTVLAPEIG
                     VIDKAVAVCEEMMRKKDGPILGLHIEGPYLNPKMAASLFIDKENPADPKEYKEILERT
                     DCIKRWDSSPEIPGALEFAQYLKSRGILSAISHTEAEFDDIKTAYNAGFTHAAHFYNA
                     MPGFHKRREYKYEGTVESVFLMDDMTVEVIADGRHLPSTILRLVYKLKGVERTCLVTD
                     ALSCAANEGKPLSDPRIIIEDGVCKLADHSSLVGSIATMDVLVRTMVQKADIPLADAV
                     RMASETPARLMGVSDRTGTLQRGKDADIVILDRKLNVRAVWSMGNLVPETNTLV"
     gene            complement(37183..38349)
                     /gene="nagA"
                     /locus_tag="ACZPB4_06220"
     CDS             complement(37183..38349)
                     /gene="nagA"
                     /locus_tag="ACZPB4_06220"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005676127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HIR1097850.1"
                     /translation="MLTQIINGKILTPQGWLKDGSVLISDGKILEVTNCDLAVVGATL
                     IDAKGMYIVPGGVEIHVHGGGGRDFMEGTEEAFRAAVATHMKHGTTSIFPTLSSSTIP
                     MIRAAAETTEKLMAEKDSPVLGLHLEGHYFNMKMAGGQIPENIKNPDPEEYIPLLEET
                     HCIKRWDAAPELPGAMQFGKYITSKGVLASVGHTQAEFEDILTAYEVGYTHATHFYNA
                     MPGFHKRREYKYEGTVESIYLLDDMTVEVVADGIHVPPTILRLVYKIKGVERTCLITD
                     ALACAASDSQVAFDPRVIIEDGVCKLADRSALAGSVATMDRLIRTMVQKAEIPLEDAV
                     RMASETPARIMGVSDRKGTLQRGKDADIVLLDRDLNVRAVWAMGKLVEGTNKLF"
     gene            complement(38934..40883)
                     /locus_tag="ACZPB4_06225"
     CDS             complement(38934..40883)
                     /locus_tag="ACZPB4_06225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HIR1097851.1"
                     /translation="MISVEGLTVEFGGFTLFDDISFVVNKKDRIALVGKNGAGKSTML
                     KIFAGLQSPTSGTVSVPKEVTIGYLPQHMQLVDTRTVREEAECAFEHIHEMEEEINRL
                     NTQLAERTDYDSEGYQKLIDRVTYLSEHFQMMGGNNYHAELERTLAGLGFSRSDFDRP
                     TSEFSGGWRMRIELAKLLLRRPDVLLLDEPTNHLDIESIQWLENFIATRANAVILVSH
                     DRAFIDNTTFRTLEIELGKVYDYKVKYSEYVVLRRERREQQQRAYENQQKKLADTEAF
                     IERFRYKATKSVQVQSRIKQLEKVERIEVDDVDTAMLRLKFPPAPRSGSYPVICEEVA
                     KRYGDHLIFDHVTLTINRGDKVAFVGKNGEGKSTLVKCIMGEITDFTGKLQLGHNVKI
                     GYFAQNQAQLLNENLTVFDTIDYVAQGDIRLKIRDILGAFMFGGEASDKKVKVLSGGE
                     RTRLAMIRLLLEPVNLLILDEPTNHLDMRSKDVLKDALREFDGTVIVVSHDREFLDGL
                     VDKVYEFGNQKVVEHLGGIYNFLEHKKMDSLRELERSTGTSTSMSGTGEAQVSHNKLS
                     YEARKELSKVIKKAEKAVAEAEARISELENGIAVIEAKLATPEGASDASLYGEYSALK
                     KELSDAMDLWTERTMELEELNTQDS"
     gene            complement(40922..>41569)
                     /locus_tag="ACZPB4_06230"
     CDS             complement(40922..>41569)
                     /locus_tag="ACZPB4_06230"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HIR1097852.1"
                     /translation="ASAGKDEYSMRFEDGIKDARGWIDYLSKDKRISGIYVLGHSEGA
                     LVGMAASVDNPKVKGYISVAGAGRPAYEIIEEQMAGQPEVIRNMVRSINTSLKEGKLV
                     PDVPIGLQALFRSSVQPYMISWYTYNPQEIIKKLKVPVLILQGDKDMQVSVKDAELLK
                     RSQPSADYHLIGNMNHLMKTCDTMDQQKQMATYTDPALPLHKDVLILIEKFVSKP"
BASE COUNT        12004 a         9747 c         8781 g        11037 t
ORIGIN      
        1 gcgatacagg ttatcaagcc gcctaaagcg atcaggattt ctacataaat ctccgcctcg
       61 ctattaacca aggatttcac ggtctgcccg gtcacgatag ctagagcgac ggcccagagg
      121 taaaaggcca tgtctcgaag ccccgcaagg aagcgatgga taggtggtat gaatctacgc
      181 aagaacaaag cgaggaaaaa cgggaataac agcaatggga agacttttcc caagatcttc
      241 aagaatgcgg cgaagaaagt aatctcggca tgcggttcca ctaatgggaa gaccagcggc
      301 acgacaatcg ctgccaatag attcgataat aaggtataag tagtcagact agaggcgctt
      361 ccccctaatt tacccgtaat cacggcggcc gccgtagcgg ttgggcaaat caggcagacc
      421 atcgctcctt cgaacacatc ccggtattcc tctctcattg gcagccagag caataaggcg
      481 gcaagcacca aactggaaac cgcttggata agcaatagcc aaccatgcca agggctgggc
      541 atcaattccc ggacagagat cttacagaag gtcaggagca gctgggcaaa aatcaaaaag
      601 ggcgtcagat acgctattaa agtgtacatg aacggctttg taggctccag aaaagtaaca
      661 ttggcgaaaa caaaataccc tatcgcaccc gctaacatgg aaatagggag tgtccatgtc
      721 ttgaagaatt tcaacataac gcctattctt ttaattcggg atgcaaaata acatctttcc
      781 accgaaagag gcaaacaaaa accgttctat tgttggctct gtctcctaaa tttcgaggga
      841 gataagccct ctttcttcgt gaaaaaagta gaaaactgag atacagtctc aaaattaagc
      901 gcatacgcta tctctgaaat acttaatcga gaagtactta atagctcttt tgctcgaaga
      961 taacgtaaat gcaattgata ttgagcggga gatacccccg tataagattt aaaggtactt
     1021 cgaaaccaag aataactcac attcaaactc tgagcgatcg attccaccga cataggatta
     1081 tcaatattcc tcttcatgaa agctcgtgcc tcattgatct tctccaccgc atctgactgc
     1141 cctaaaaaac gattcttctc tttataatat atctccccca tcagataaaa gacaatacta
     1201 gaaataagtt gctgataacc gtttcgctcc tttatagcat gagaaactat ttcctcatac
     1261 aaacctataa ttgtaacatt cacccctatc tcatagacag gattctcttt tgagaaaaat
     1321 ttattagaaa tccaaccctc tattaaattg cctctaaaac ccacccaata ctcgtaccaa
     1381 ccattttccg ctggagaata ggtatgccac tctcccggaa acaacaagat catcgtccct
     1441 gctttaatct tttttcgttt aaaagactgg gattcaaaga acccacaacc ttcagaaatg
     1501 tacaccaatt ggtactccgt taatatacgt cctttttccg ggttgaaaga atacgtcaaa
     1561 ggatgttgtt gcctgacagg gtaaatacta tgcggaggta tggattgata accgactgtt
     1621 gtaaccatca tcccccatag ctcatccatc ggactaacat tcagataacg aatgttatta
     1681 ttttgtgtac tcataaaaag atatcctcct tataacatta ctaaataatt gaccaaagat
     1741 aatatatttc acacacatga cagaagatat gaagtactac ttacccgacg cagtatatat
     1801 cctaagggac ttgaagtata tcttctacga caagggaagt tcactttctc taaactaaac
     1861 tatcactttt ctaaaatata aaatcaaata gataaaacaa gaccaaaagc aaccctatat
     1921 ctttgctgtt ggtcaaagaa gataatatga aactaaaatt caatctataa aacatggaaa
     1981 acaaaaaaat aaatgtagga ttggttggga tgggattaaa tacctattgg tcccaatttg
     2041 aaggactcta tgaaagactt tgcaaatatc agaaaaagat agcagactct ttaacacgtc
     2101 cggatataag tataatcaac gctgggatct tagaccgtcc ggaggaagca aaaaacatcg
     2161 cagatgtttt atcgcatgaa aatatagaag tactttttgt ttatatctcg acgtatgcgc
     2221 tatcatctac ggtattaccg ttggcacaac gtctcaaagt tcccataata ctattaaaca
     2281 tacagccctc ttctcacata gactatacat atattaatag tttaggagac cgaggtctca
     2341 tgactggcga atggttagcg aattgccaag catgttccgt ccctgaattt gcgaatatac
     2401 ttatccgttc cgacctacct tttaagatcg tgaccgggta tttggaagac aatgcgactt
     2461 ggaccgagtt aaacgactgg ctcgacgcaa ccgtggttat ggcaggtatg agagagcatc
     2521 gtatgggtat attaggccat tattattgcg gaatgttgga tgtttactca gatatatccc
     2581 agcaatcctc ttctttcggc acccatatcg aactactgga aatgtgcgag ctaaaagctt
     2641 acagagatgt ggcatcagat ctggagatca aaaaaaaaat aatggaattc caacgtaagt
     2701 tcgaggtagt cgctgaatgt gaagaaacgg agttaatacg tgcggctcgc acatccgtcg
     2761 cattagacaa attaatcaaa agccatcagc taggctcaat ggcttactat tacgaaggtt
     2821 atcccggcaa tgattatgag gatattgtaa cctctgttat agcaggtaac accttattga
     2881 ccggcaagaa catacctata gctggcgaat gcgaggttaa aaatgttcaa gccatgaaaa
     2941 tactctccct gctaaaagcc ggcggatctt tttccgagtt ttatgccatg gactttaaag
     3001 acgatgtcat attacttggt catgatggtc ctgcccactt cgccatgtcc gatggtaaag
     3061 taaaactcgt acctcttcct gtttatcatg gtaaaccggg caaaggatta tccattcaaa
     3121 tgaccgtcaa gaatgggcca gtcaccctat tgtctgtttg tgaaggaaag gagggaatat
     3181 ttttattggt agccgaagga gagtccgttc cgggccctgt tctggagata ggtaatacaa
     3241 atagccggta tcgtttttct tgtggggtaa aaagctttat ggaaaactgg agcaaagctg
     3301 gtccgtcaca tcattgcgct atcggaatag gtcatcttgc tagcaaactg gaaaaaacgg
     3361 gatttttatt aaatattcct gtcataaaga tcgcttaagg gatcatctta acatctctaa
     3421 taaaaaagac ttcttaggac tgccatatat gactttccca tagtcctctc tgcaaatatc
     3481 atagttctat cggaactatg tctcttttat atttccactt tgcaaaaatc taaaaatatt
     3541 agtaaccaca tattaaaaaa atgatattta atgtttgata aatgatattg ttcttccaat
     3601 aaatatcttt ttcatatagc tataatctca taaatacatc tgcaagtttc atagttccga
     3661 tagtactaat atcaaattag atgttgccta tgaaataaaa agtattagac ctttaaatca
     3721 cctattttat tggtaatcat tttaccacca acaatttaat atcaatctaa taatttaatt
     3781 atttaaatta tgaaaaacat tcttttcaca acgaggaaga acaatggtgt tccaatgtta
     3841 aaaagcaccc ttcctattat tctatttagc atgttcccag gaattgccgg tattgcggca
     3901 acggaatctg cgacactaga caatcctttg gtttcaacgg tgactcaaca aaacaaaaaa
     3961 gtcagcggtg ttgtttatga cacaaatgga gatcctgcca tcggagcaaa tgtcatcgta
     4021 aaagggacaa ccaatggaac cattacagac atggatggta aatatacgtt ggaagtaccg
     4081 gcaaatgcca ttttgcaaat ttcctacatc ggatacaata cccaagaaat accaataggt
     4141 aataaaacaa caatcaacat aaatcttaaa gaagatacac aagccctaga cgaagtagtc
     4201 gtcgtagcct acggtactca aaaagcacgt tcagtaacag ggtctatgag taagcttgat
     4261 gctagtgaac tatctgatat gccggtttcc cagattgggg aaaaattaca aggaaagttc
     4321 tctggagtac aaatcaacca agccaatgga gaaccaaacg gcggtttagt gatccgtgtg
     4381 cgtggtgcgg cttctatcaa tggaggaaac gaaccattag tggttatcga tggtttcccc
     4441 actacttccg gtttggcatc catcagcccg gatgagatcg agaatatcac tgtattgaaa
     4501 gatgcggctt ctgcctcttt gtatggatcc cgcgcagcca atggtgttat cttggtaact
     4561 acaaaaagcg ctaaaggagt aagcgcaggt aaaccgcata tcgatttcag cgcatacttc
     4621 ggaattgaca aggtctccaa tcaaggaagg cctgatttga tgaatgcaca agaatttgcc
     4681 cagttcaaga aagaatatta tgaagatcaa gcactttacg aaggttatac aggaggagtt
     4741 cccgaatgtt atcaaaaccc acaagcaata ggtaagggca cggattggtt tgatattctt
     4801 ttgcaagacg caatcacaca aaactacaac ttaggcctaa gcgcagcagg agagaaattc
     4861 aaatcagctg tcaatatcaa ttacaacgca aaagaaggta ttattttgaa cacttactcc
     4921 aatcgtttcg ccgcacgtgc caataacgta tatgaagcat ctgaccgtgt ttcattcgga
     4981 ttaaatgtct ccggatctta cacaatcggt caattaacag acggattagg tggtggacgt
     5041 tacatcatag gttctgccat gttgatggac ccgcagttga aatacaagaa tgatgacgga
     5101 acttatccta tcgcctatac gcaaccgggt atgtttgcca accctaacta ttatcttgta
     5161 cttactcagc gtcagaatcc ttctaaaacc ttcagaggca cggtcaatgc ctatacagac
     5221 atcaagatca ttgatggctt gaagtatcgt ttaagtgcta atgcggattt ggcgaacaac
     5281 tctcgttcaa actggattcc atctaccgca aacggagcta tgttctccgc tcctcctcaa
     5341 ccagccacag gttcctatca tacttctaat tacgtaaact ggctattgga aaacacgtta
     5401 acttacaaca agacaatcgc aaatgatcat aaccttgata ttttagtagg ttatacgact
     5461 cagaaaaaca cacaggaaaa cgctcgaatc gacgcttccg actatccgga tgatgagcta
     5521 ccttggtttg gagccgcaat cacaagaaca ggaaactctg atgctgataa atggggtagc
     5581 tgggctatga tctcttattt gggacgtttg aattacgact ataaagaaaa atatatctta
     5641 tctgtagcat tccgccggga tggttgttcc cgatttggtt caaatgcgaa attcgccaac
     5701 ttcccgtccg tttcagtggg ctggatcgct tcagatgagc ctttcatgga gaaatacgat
     5761 aaagttagcc atttgaaact tcgcggtagt tatggactgg taggaaacta caacatcgga
     5821 aattatacct atttggcttc cgtaggctcc tacaactatg tgacagatgg atctatcacc
     5881 gctggacgtg ctctttcccg tatcggaaac aacgagctga cctgggagac aaccaaacaa
     5941 atggacttcg gtgtggattt agggttattc aacgatcgtg tattcttagt ctatgattac
     6001 tacagaaaat ggacggatgg tctcttgtat cagattgata tcccctactc ttccggattc
     6061 agcaatattc aatctaacat cggtgagttc catttctggg gtcatgagat cagtttggaa
     6121 acaaagaata tggtaggagc ctttaaatgg aatacgcaga ttaatgtatc catcgaccga
     6181 aacaaagccg ccaaattggg gacaaacgat actcccattg gaggcttcaa caaccaagaa
     6241 gattacaacc gtaccgctgt agggaaacca ttaggtatgt tctacggata cgtatacgac
     6301 ggagtattca tgactgaggc tgaatatgag gcaggtccta agcatgcgtc atccatggtt
     6361 ggtactgtac gaatgaaaga cctgaatgga gacaacaaga ttgacatgga cgatagaact
     6421 tatattggaa atccgaatcc cgacttcaca ttcggcataa cgaatgaatt ctcatggaga
     6481 aactttgatg ccagcctgtt attgaccgga tccgttggaa acgacatcat tgacggcaca
     6541 ttggagtgga cagagaatat tgatggcgta ttcaacgtac ataaaggtgt agccaaccga
     6601 tggcgttccg tagacaatcc cggtgacgga caagttcccc gtactcgtac aggtacaaca
     6661 gagctattcc gttatacaaa ctctcgctgg gtatcaaacg gttcttattt aagggttaag
     6721 aatttgaccg taggctatac tattcccatc aagaagaatc catacgtgaa aggactacgc
     6781 atttatgcaa gtggacagaa cttattgact tggacagggt ataaaggtat gaacccggaa
     6841 gtcagtggca aaggtgccag tggcttatat caaggggtag acaataccgc ttatccggta
     6901 gctcgtacat tctccttagg cgttaatgtt aaattttaaa agttaaatca gtatgaaaaa
     6961 aagatattta tatgttgcag ctttggctgc attgttgaat ttttcgtctt gcagtaattc
     7021 ttttttggac ttaaatccgg atacagccat tacagcaaat acattctaca aaacagcaga
     7081 gcacttcgac caagcactag tcgcttctta cacagctttc agaagcattg ctcaaaccgg
     7141 aataatgatg gatgaaatgc gctcggataa ttccttctat accttctact caggagatag
     7201 aggcccatac gcttcaacgg aggtactagc cttgttcttg gatagcggag atcctattag
     7261 ctggatagag acccgataca aagacaatta tacttgtata ggtcgtgtca atacaatctt
     7321 gaatcgtttg gaatcctctg aaatgacaga ttcagaaaaa aacgcagtaa aagccgaggc
     7381 tctattttta agagcatact attattacga cttggttcag cactgggggg gagtcccttt
     7441 gatattggag gaggtacaga acgaagctga tgcgtttaaa gcaaaatctt cagctgaaga
     7501 ggtttataac caaattatca cagaccttac ggaagcgatt acgttaggtt tacctgtgcc
     7561 ttctaaattc ccgcaaagcg gacgagcaac gatgggagcc gcaaaaatgt tgagagcata
     7621 cgcttacatg tctcaacccg atcggaatta tccggccgca gagcaagact tgaaagatat
     7681 cacaaagatg aattatacat tgttgagtga ttacaatgct gtatttgaca aagcgaataa
     7741 aaacaaccaa gaatccatat tggaagtaca atacgccaat gacggtagta cagatgagtg
     7801 gaatcgtatt ccttggaata taatccctaa atgtagtaac aatgaagtcc ttatgggtat
     7861 cgctggttcc aattatgtag gtgcatggcc tggtggtacc gccggaggtt ggaatgttcc
     7921 cacggatgaa atgatccaat cttatgaaaa gggagacaaa cgtttagagg catctatcgc
     7981 agtggcagaa ggaacgttgg atggtgataa cttcacattc gaagaagtta aaagcccgat
     8041 cggttacacg ccagctgcag gaaaagactt ccgttacttt gtaaagaagt attatcatcc
     8101 accttacacc tattcactga gggcagacga taatttcccg gtttaccgtt actcaggcgc
     8161 cttattgcta ttatcagagg cattggtgaa acaaggtaag aacgcagaag ctttgcctta
     8221 tattaaccaa gtaagagaaa gagcgggact taaaccttta gcgtctgtaa cattaaacga
     8281 tgttatggat gaaatgcgcc atgagttggc cttcgagaac aaacgttgga cggatttaat
     8341 ccgcaatgat caagccattg aaaaaatgac agcattcggc aagaccatga aagctctcta
     8401 tccgtggatt ttaccttccg cattcaacgt cacgaaagag cgtttcgtat acgccttccc
     8461 gagacgtgaa atggacatca attatctatt ggaacagaat cccggatatt aatataatta
     8521 ttccttttga agagggccgg caatagccag ccctctcgga gattacacta attttatagc
     8581 ggatttatat aaacaattta atagcatgaa aacacaggaa ttagtcaagt atctatcttt
     8641 cgctattaca tgcggatatt tatcttgggg cttaacgagt tgtgatgggc aagaagccat
     8701 gagttccgat aattgggcta cattggaaac cggatttaaa gatccgaaag cagaatatcg
     8761 aacagcacct ttcgccgtat ggaatggtaa ggtgacaaaa gaagaggtag aacggacaat
     8821 ccaagagttg aaagacgccg gatctggagg agcatttata catccacgtc caggtctcat
     8881 taccgaatat atgtcagacg aatggtactc tttgtacagg catgctgtcg actatggaaa
     8941 aaaaaatgat atgaacatct ggatctatga cgagaactca tatcccagtg gtttcgcagg
     9001 tggacatgtt cccgaactga tgccggagtc ttataatcaa ggacaaggtt tggctttgaa
     9061 gaaggttgag ctattacccg agaagttaga caactgtttt atctgcctaa aaaaagaggg
     9121 tgacaaatgg aaagacatca caaacgaaat agactcctat aaacaaaaga aaggggaata
     9181 ttacctgtat gagaaaacat tttatggacg ttcggattgg tatggtggat attcttatgt
     9241 agatgtcatg gtaaaaggcg taaccgagaa gttcatcgac gtaacgatgc aaggttatga
     9301 gaaagttgct aaaaatgagt ttggcaagac cataccgggt atttttactg acgaacccaa
     9361 tatccagagt tccggaggtc tgcgctagac tccggatttg ttcgacgtat tccagcaaaa
     9421 gtggaattac gatttaaggc ctttattacc tttattagaa gaagaggttg gtaactggaa
     9481 agaggtgcgt cataactaca tggagacctt gttacaatta tttatcgatc gatggtcaaa
     9541 accatttcat tcctattgcg agcaaaacaa tttacaatgg acaggccatt actgggaaca
     9601 tggctggcct tatatgaatg acggaccaga taatatggcc atgtacgctt ggcatcaagt
     9661 cccggccatc gatatgttgt tcaaccaatt tgatgataaa agtcccgtcg cacaattcgg
     9721 taatgtacgt gcggtaaaag agctgagaag cgtggcaaat caaatgggat atacccggac
     9781 tttgagtgag acatacggtg gaggaggctg ggatgagacc ttcaaagact tcaagcgttt
     9841 aggtgattgg gaatacgtat taggtgtcaa ttttatgaac caacatcttt cgcacatgac
     9901 attgaccggc gctcgtaaat acgattaccc tccagtattt acatatcatt ctccttggtg
     9961 gtctaactac aagagcttga atgattacta cgcacgctta tcttgggtca tgagtaaagg
    10021 tgtacaagac aatgacatat tggttatcga accgaactct accctatgga gctattattc
    10081 tcacacaaag agtagcaagc aattgatgga agtcgggcaa gccttccaga cctttgtgac
    10141 aactttagaa aagaggcaag tagaatacga tctgggctct gagaacatca tcaaggatca
    10201 aggagccata aaaaacggtc aattcgtcat cggaaaagcc gcttactcaa cggtagttct
    10261 tcctcctttg atggaaactt taaataaacc cacattcgag ttactacaaa aattcgttca
    10321 gcaaggaggt aaagtggtac gcttctcttc tcccaatcgg attgatggcg cagaaaacgg
    10381 cgaattagcc aaagtgttga gcgcacaatc ggtcatatcc tacgatcaat tgaatgaaaa
    10441 agtcattcaa gatgcttttc ctccaaaaga ttgcaaattt tcctttaagg gaggcgactt
    10501 attccatcaa cgtcgtaagt ttgcagatgg ggaattgctg ttcttagtca actcatccat
    10561 gaccgagtcc gtagagggaa ccatagccac agtcggcaaa tctgcgatcc gcctagatgc
    10621 catggagggt aagatttatt cctatccttc cgttgtagac aatgggttat tacatacaga
    10681 tttccatttg gaacctgcag gaagtttatt actttattat tccaaccata tattgaaagg
    10741 atatccggaa gcacccgcta tcgccggaaa tacgaaattg gcagctagca aaagtgttga
    10801 agtaaaacgt ttgaaagaaa atgcattgaa tattgatttc tgtgatgtat ccgtaaaggg
    10861 aaaaactcag aaaaacattt attttgcaca agccgccgat atggtattca aggaatatgg
    10921 ttttacaaat ggtaatccat ggaacacttc tgtacaatac aaaagaaata tcttggatag
    10981 ggacaccttc aagaccggag gattcgtcgc aacctaccat ttcaacgtga atgataagtt
    11041 tgattattct acgatgaaac tggtagctga acgtcctgag tttttctccg tgaaagtaaa
    11101 cggacagcaa gtacaggcca ttccttgtga atggtggcta gaccgctctt tcggagtata
    11161 cgcaatcgga aacatggtga aacaaggaac caacacggtc gagatgagtg tgacaccaat
    11221 gagtatattc gcagagatcg aaccaatcta tgtgatcggt gattttgcgg ttgttcctga
    11281 aaacaaagga tggagtatta gcgctccggt ggagaaactg accttgggca gttggaaaaa
    11341 acaaaaacaa ccattctatt cttgggatgt ttcctatacg aaggaatacg atgtgaaaga
    11401 tacctccaaa tcctacacca tccagttgaa cgcttggaac ggtacggtca ccgaagtcta
    11461 cgtgaacgga gagaaagctg gaatcattgg gtttgatccg tatcgcttga atatagcttc
    11521 ctatttgaag caaggaaaga atcaagtgga agtccgtgta ataggaagcc acaagaactt
    11581 gttaggcccg cattacaaca acccgaatcc aggtttagcc agtccttggc attggaaaaa
    11641 tatccgcaag caaatacctg gatctgacta tcagatgctg gattacggct tgatggaaga
    11701 ttttgacctc gtttattaat agagataaat ggcatcaaag catgattata ccctcctgat
    11761 tttccagcaa gaacgtataa catgttttga tgccattttt taatcacaat tgatttttta
    11821 gctatgttta aacattcata taaatacgcc ttgatggtat gcttgctgtt attgagcaca
    11881 tcacccatat tcagtcaaaa aagcgatgaa ttgagacatt cattcaacgc tcctcccaat
    11941 caagcgaaac cccgtgtgta ttggtggtgg ctctataacc gaataaacaa agaaggtatt
    12001 acccgagatt tgcaggagtt caaggagaaa gggatcagtg gcgtgaatct gatctgcacc
    12061 ggaggatatg caggtgacaa agctttagaa ggaatcaagt ggctcagccc ggaatggcgt
    12121 gaacttttcc ggcacgccgt cagtgaagct aaacgactag atattgaatt gggattcaac
    12181 ctgtccggag gatggacaat gttgggtcct tgggttacgt atgataacgc aatgaaaaaa
    12241 gtagtccaat cagatacgat catcgcagga ggtaagaaag tctccatgaa actggctcaa
    12301 ccggaaaccg tggagggcta ttataaagat gtctgggtac aggctttccg tattgacacc
    12361 accaagaagt tggtagacgc agaatctgca aaagacctaa ccctatacat gaaaccagac
    12421 ggaaactttg aatggaaagc ccccaaagga aattggttga tcctccgcac aggatatacc
    12481 ttgaccggac atacttggag ccgttggttc gcctatcccc aaggagacac tttcgcagaa
    12541 ggagccggat atgagatcga ctatttaagc aaagcggccc tcgacaacca tttcaaccac
    12601 ttgggaacaa ttattctcga cgaagtcaaa aaggcaggag gcaatttagc ctatttctgg
    12661 tcggatagct gggaatgcgg gaaattaaca tggacacaag atttccctga acaattcatg
    12721 cactaccgga aatacgattt gaaaccttat atggccatat tatccggata tatagttaag
    12781 gattctctct tttgcgaacg tttccaggaa gacttcgatc gcacgattca agattgtatc
    12841 gccgataatt actacggcca tttttacgat ctctgccata agaacggatt gaatgtcggc
    12901 aatgaagccg gaggacctaa tgatattcca ccccaggatg tcttaaagaa tctaggacga
    12961 tgcgatattc ctgccggcga gttttgggtt cattacaaat tgccggaaga cggaatgaac
    13021 tcccggaaaa gtgcccggtt gaatttgaaa caaaccgcct ctgccgctca tatctatggt
    13081 agacgtgagg cgcaagcaga agctttcacc caaatggaac aggatcgtac tcattggtcg
    13141 ttaggcccgt atgatttgaa accgtatgcg aatgacgcat tctgcgaagg aatcaaccgt
    13201 tttatgttgc accaatcaac ctgccagcca cccgaggatg gaaaaccagg ttatgagttt
    13261 tgcgctggac agcattttac acccaatctt acttggtggg aacaatcatc cgcattcttc
    13321 tcttatttat cacgatgcca atatctattg caagaaggta aattcgtagg cgatgtatgc
    13381 tattatattg gcgaacagac tccatcactg gttcctcctc actacatcat tccgtcgtta
    13441 ggtttaggat acgactgtga ttatacgaat gtggaggtct tgttaacgag aatgtccgta
    13501 aaagatggta ggattgtctt gccggacggc atgagttatc gcttactcta tctccaaaat
    13561 tgtgtctcac cagataagga aatatgcgag gccgtttctc gctaccaaca attagaagtt
    13621 cctaccgaag catcggaaat gatgtcccta gatgtgctta agaaactacg tgaattgatt
    13681 atggatggag caaccgtcat aggcgcacca ccaacaatgt ccgctggact agacaactat
    13741 ccttatgcgg acaatgaggt acgtaaactg gcctcagaga tttggagaga cttggatggg
    13801 aaaaacatca cagaacgtaa attaggtaaa ggaaggatca tctggggcaa aaccgcacgc
    13861 gaggttttgc tagcggatgg aattggacaa gacttcgcct atctgaacca gactgcagaa
    13921 ccggaaaaat tcaattacat ccaccgttca ttagacgatt gcgatatata ctttgtcatc
    13981 aaccggacag gcaaacaaac ttctagccaa tttacgttca gagttcaagg taaacaaccc
    14041 gagatttggg accctgtgac aggcgagatg agaatagcct cctctttcac ccagcatgat
    14101 ggatatacga ctgtcccctt agagttcgtt ccgtacggct cttactttgt cgtatttgac
    14161 aagacaatct caacggataa gcaaggagaa ggcgatcgta atttcagcaa gctggaaata
    14221 gcacaagatt taagccactc ttgggaagtg atgtttgacc caactatggg aggcccgcaa
    14281 aaggcctttt tcgaggattt atccaattgg atagatcggc cagaggaggg tatcaagtat
    14341 tattcgggga cagccactta ccggaaatca ttcgaccttt ctttccccaa agggaacgat
    14401 ggacatatct acttagactt aggaaatgtc aagcatgtct catcggttcg gatcaacaac
    14461 aaggacttag gaatcttatg gtgtaccccg tggcgagtag atatcacaga ctatgtaaaa
    14521 gagactggta acttagtaga aatcgatgtg atcaacttat gggccaatcg agtgatcggt
    14581 gattggaaac ttccaaaaga acaacgattt acacgtactc atgatgtttt tcgctttgat
    14641 atgttaagag ctagtacccc gcttacggac gcaggtttgt tagggcctgt tagcattcta
    14701 aaagagaagg tatgggatat ggttacccct attacaaaat aaataatgat gaagaagata
    14761 ttatttttta taatcggaat agtgttttgc ttatcttctt ttgccacaga tacacgaagt
    14821 accgccttgg acttatctcc cgcaaagtgg atatggtatc ccgcaggtag aaccttgcaa
    14881 aatacatttg tattattccg gaaagatatc atattggaca agaaacctca taaggctatc
    14941 ggctggatat tggcagacag ccgatatcgc ttgtttgtca acggaaagcg aatccaatgg
    15001 gggccagccc cttccgatcc tcgctggcaa gaggctgatc caatagactt aaccgcattt
    15061 ctcactgaag ggaaaaatgt aatcgctgta gaagtttgct ttttcggttc tggagatggt
    15121 acacatccaa tgggaaagcc cggatttata ctaaacctag acatggatca agaaaagtta
    15181 gtgaccgatg cctcatggga ttgttttctt gctaaaagtt ggcaaccggg acaatataaa
    15241 cgttggttcc tacgctcctt acaggaagaa ttcgatgctc ggctatatcc atacggatgg
    15301 gatacctccg atttcaaacc agacgaaaat tggacaaagg ctatccttgt aagccaagat
    15361 ggcaaggaac cttccgtgtg caacagctcc tccgagtatg tctgggaaat attcggtaac
    15421 aagcaattgt ccgagatacg gaaaagaagc attcccgcta tgcgagaatt tgatttccat
    15481 gccactacgc tagaagaatc tatgtggatc cattggaaaa gaccggtgga agattatttt
    15541 gatttgttgg tatcagacgc tttcgagaca atcgataaac ctatcacaag atctctcggg
    15601 gatggtgagt gggaaatatc accacagggg aactacgcag ccgccctgac attctctttt
    15661 ccggaacaag gtgtcggatg gcctcatttc acgatcgacg cacccgaagg aaccatagtg
    15721 gagctactgg ttcatgaggc tcatcagaaa ggaggtccag cacttatcaa ctcgcatttc
    15781 aattcatggt cacgcttcat ctgtaaagaa ggaatcaacc attttgagac tttcgatttt
    15841 gagagtttca gatggttaca actgcatatc cgcaacttca accgtcccat aaaaatagct
    15901 tcagtgggta tgcgccgtcg tatctatcct tggaaatcgg atcctactat cgttatatcg
    15961 gatgatacca tccaacacgt agtcaatgcc gccgtgaata cattatacaa ttgcgcccaa
    16021 gaaactctag tagatggaat ggctcgcgaa agacaacaat acagtggaga cggaagtcat
    16081 caactacacg ccgtaatcca aacactaggt gatataacgt taccgtatcg attcgtgaac
    16141 actttcagcc aagggctttc cattgacgga tatttcatgg atagttggcc cgcatgggat
    16201 cgtttagctc gtacggttga acgacaaatg catttaacag gttggggccc aatattggat
    16261 catagtattg gtttttgctt tgatgctttt cattactata tgtacacagg cgatctacaa
    16321 ggattaaagg aggtttatcc cagactactc tccttcttca gctatctcta taaattaact
    16381 gacaaatcag aacatctggt tccggtggag aacttaggaa tgtgctctgt ctatatcgat
    16441 catgaggctt ataagcaaac gaaacataag caactcgcac tcaatctata tatcgttgcc
    16501 atgtgccaaa atgccttatc tacattatgc caagcgtttg gtgatactca aaaagcagat
    16561 gagatcaatc agtatgcggc ggacattcta caaggatgta tccaaaaatt ttgggacaaa
    16621 gaacaacaag tctatgtaaa caatctacca tggaaagacg aggaaggaga aattcgttac
    16681 tgcgatcgtt ccttatcgac cgccttgatc tttgatctat gtccaaacgg agagaccgca
    16741 aaaacattgg atttattaga acagagtcca gcagaaatgg gggtgtcgta tccctgtaac
    16801 gccgtatggc ctctatgggc tttggctaaa tacaggaaga tcaacactgt cttatccgac
    16861 ctaagggaaa aatggggcaa catgagttcc gtatgggcca ataatacgtt gcaagagttt
    16921 tggaaggctt atcccgacga aggttctcaa tggagccatt gtgccatgta tcccttgatt
    16981 gccctcaacc aaggcatcgc tggagtatat ccactcaaac ccggttgtga gaggattaag
    17041 atggaacctc aattaggtga tcttgagcat atccgttttg acgtgcaaac cctcaaagga
    17101 gccattcaac tctcggcgca aggcataaaa gggaaacgtg aactacgatt gcaagtaccg
    17161 gactctctct ctatcgagtt aagactggat aaacgagaaa aggtggattt gccactttta
    17221 cgcacggaaa aagacggaat caacgtatat gagatcacac atcccggttc ttatgtatta
    17281 aaactaaaat atacttaatt gttggcccat aacattctaa attcgttact atatgaaagg
    17341 aaatagagta attttaaaca cagccattct cttgataagt tcaatgagtt tattaaagct
    17401 gtctgctcag aatgaaaatt catgtgtacc tacgaatctt cgttgtgagc atttggaacg
    17461 tcctttagga atcgaccgcc agtctccccg atttagctgg aatttgtctg atacccgaaa
    17521 tggagcaaag caaacggctt atcagattgc ggtaggaaaa gactctttgg cgctatctaa
    17581 ggggaaaggt actatttgga aaaagaagat atccggagac caaatgctga ccacctatac
    17641 gggaaaggcc ttagaacctt gtacacgtta ttattggagt atcagcgttt gggacaagga
    17701 caagaagaaa tcccaatcgg ttatctcctc cttcgagacc ggcttattga cccaaagaaa
    17761 ttggcaaggc aaatttatct cagacggaaa ggatatggag tctcgcgaca ctccctattt
    17821 caggaaacaa atctcattaa acaaagaggt tgaatccgct cgtacctata ttgtcgcagc
    17881 cggtctctac gagttatcta tcaatggaga gaaagtcgga gatcactacc tagatcccgc
    17941 ttttacggat tatggaaaac gtttgctgta tgtgacacat gacgtgacaa atcttttgcg
    18001 acaagggaag aacgcaatcg gtgtaatctt aggaaacgga tggtataatc atcagccagt
    18061 cgcagaatgg aatttccaca atgctccatg gcgtgacaga ccatcatttt gtatggatat
    18121 tcgtatccgt tataccgatg gaacagaaga gatcattgcc tcggacaata gctttaagac
    18181 aaactccggg cctatcacgt tcaacgctat ttatctagcg gaaaaccatg acttccgcaa
    18241 ggatatgccc aattggaata agccttcttt tgatgactcc tcttggcaaa cagcgacaga
    18301 agtagaaaag ccggatgtta tcatatcctc ccaaacaatg catcctattc gtatcacaga
    18361 ctttcgcaag ccgattgagg tgaaaaaact aagtgataca ctttatctgt ataactttgg
    18421 gcagaactgg tcgggtatca ccacttttac cgtacaaggc gaagctggaa cgaaagtaaa
    18481 attacgtcat ggagaacaat tggattcccg gggtaaacgt ttgtttgatg ataacaatac
    18541 ccaattctat caaaacgtaa acgaaccgct caagtatgga aaacatccgg aagacgaatt
    18601 gttccaaacg gatgtgctta tcctagacgg gaaaaagaac acgttcactc cgcatttcaa
    18661 ctataaagga ttccaatatg tggaagtatc ttccgataag cccttggaac aggacaaaca
    18721 agatatgacc tcccatttta tccataccga cttaccacaa atcggcacat tcgaatgctc
    18781 cgactctttg ataaatcgtt tatggcgtgc taccaattat tcatatctgt cgaacttagt
    18841 tgggtatcct accgattgtc cgcatcgtga gaaaaacggg tggactggcg acgcacattt
    18901 agccatcgag accgctttat ttaattacga tggtatcacc ttgtatgaga aatggctggc
    18961 ggatcatcgg gataatatgt atgaaaacgg acggttacac tgtatcattc cctccggagg
    19021 ctggggcagc gacatcgtag actggacttg ttccgtaacg cttatccctt gggcgatcta
    19081 tgagttttat ggagatcaga cctgtttacg tgataattac accgagatga agagacatac
    19141 cgattactgg ttgagtaagt tccccgaagg tttagtagga gatgccggat tgggagactg
    19201 ggtacctcac aaagctgtag ctaaccgaga attgtcggcc tctatctacc attacaaaaa
    19261 cgcagatatc atgtcacgca cagcgaagct attcggttat gaggaagagt ataaatatta
    19321 taagaacgaa gcggagaaaa taaaagcagc gatcaataat aaatacctca acaaagaaac
    19381 cggaatctac gctagcggtt atcaaacaga acagagcatg ccactctatt ggggtatcgt
    19441 gccagaagaa ctgaaagcga aagtcgagga acgtttatcc gaacgtgtac acatgaataa
    19501 ggatcatctg gattttggca tcatgggttg caagaccgta ctgaacgcat tgaccgaaag
    19561 tgggcacgta gaacaggctt tccgtatagt cacacaacag gactatccct catggggtaa
    19621 ttggttgaga caaggggcaa ctactttgtt tgagaactgg gattataatg gattggcgtg
    19681 gggatactca caaaaccata tcatgtatgg agaaattggt gcctggttct ataaagctct
    19741 tgccggaatc aatcttgatc cacagcaacc cggttttaaa aacatcctgt taaaaccgca
    19801 cttcgtgaaa gagcttacgt atgtgaaagc ctcttatcat tcaccgtatg gagaaattat
    19861 ctccgcatgg aaaagagtgg gcgacaaagt gatttatcaa gtgactatcc ccgctaatac
    19921 aacggcgact ttatatttgg agcataaaga cgtaccgaaa actttatcat caggatctta
    19981 tgaatttaaa attaaataga gtagatatga gaattttgaa taagacgatt ttatcgggaa
    20041 tgctgcttct acaaatgttc gcaatttgta cacaggcctc ttccttgaaa gtgaaccacc
    20101 tcaaatgcga agaattggta aatccgttag caatagataa tacgacacct cattttagtt
    20161 ggcaattgaa tagcggctgg caaggagagc aacagactgc ttatcaagtc ttagtagctt
    20221 ctgacaggga acgactgaat gaaaacaagg ccgatttatg gaattctggt aaggtgacct
    20281 cctccgcatc tacttggatt ccctatcagg gaaagctttt ggccgctaaa agttttgctt
    20341 attggaaagt acgtatttgg aataaggatg gagaagtatc cgaatggagt actcctgctt
    20401 ctttcggtat tggcttattg tccccacagg attggaaggc gcaatatatc ggtataaaca
    20461 atgaggatcc tcaatctccc ttattgagaa aaacgtttga atggaataag aagggagata
    20521 agatgctgtt gcatgtcaac tctttaggtt accatgaggt gtacttaaac ggttcgccgg
    20581 taagtgatgt tgtattgacc ccagcggtct cacaattcaa tagacggtca ctttcggtca
    20641 cctacgacat caccaactcg ttgcgaatcg gtaagaacga attggttatc tggctgggaa
    20701 aaggttggta tcaagaccaa cttcctggtg tcgtaaaagg cggtcccttt gtccgtgccc
    20761 aattagaagt gcgaaataac aacgtctggg aaacctttca ggccacagac gcttcttggc
    20821 tggcacgaga aagtggttac acttcattcg ggacttggcg gcctcatcaa ttcggaggcg
    20881 aggagatcca tgcgaaaaag ctgatcgcct tggatgccgt ttccctgaac aaggtaaact
    20941 gggcaccagt caaagttgcc gatattccag aacacaccac ctccccacaa atggtagaac
    21001 ccaatcgaat ccaactagaa tttcacccgt tgtccataga agcatccgga gacactgcct
    21061 ggattttcga tatgggaacc aatctgaccg gatggacaaa gatcaagttt cctcctttag
    21121 agaagggaca acgggttcgc atcagttatt gcgacttttt ggataaacaa cagttccggg
    21181 ataacttata tgaggattat tacatcgcag caggcaaaga gcaagagttt tttatcaaca
    21241 agttcaatta taaggcatat cgttacctga aggtgtccaa cctaaagcag gcaccggcat
    21301 taaacgatgt tacggcctat ttgatccata cggattattc aagttcctct tcttttgctt
    21361 gctctgatga agatttgaat gcaattcatg atatgataca atacacccta cgctgcttaa
    21421 ccttgggagg atatatggta gactgtcctc aaattgagcg tttgggatat ggtggcgatg
    21481 ggaatgcgtc aacacccacg gttcagacga tgttcaacct tgttccgctg tatacgaatt
    21541 ggatgcaagc ttgggtggac tgtatgcgca ctaacggaag tatgcctcat acggctccaa
    21601 atccgtatgc agctggtggt ggaccatttt ggtgcggttt catgatcgca ggttcttggc
    21661 aaacgtatgt gaactatggc gatgctcgtt tgttggaacg ctattatcca ttcatgcagc
    21721 aatggctgga atatgtaaaa gaatacacgg tcgatggctt attgaaaaca tggccgaata
    21781 cggattatcg aaactggtat ctgggagact gggcaacacc ggaagggatt gaccaaacag
    21841 atccccgatc ggtagaccta gtaaacaatt gtttcgtagc ggtttgttat cagacaatgg
    21901 ctaagatcgc tcaaacatta ggcaagccta acgaccagaa actgtatgaa agtaaaaccg
    21961 agcagttgag aacattgatt cataaaacat tttacgattc aaaagaggct agttatggta
    22021 ctggcacaca gatcgagttg gtttatccga tgcttgctgg agttactccc gaatcacagt
    22081 tgtctaactt gttaaacaca ttgtataaaa acaccgccga acgtttccgc ggacacctag
    22141 caaccggcct agtggggatt cccataatta cggaatggtg catcaagaac caacaagtca
    22201 acttcatgca ccaaatgttg aaaaagcgtg attatccgag ctatttgtat atgattgata
    22261 acggtgcgac cacgacctgg gaacactgga acggagaacg cagtcatatc cataactgct
    22321 acaacgggat cggtacctgg ttctatcaag ccctagcagg gatcatgccg gacgaggctc
    22381 atccaggcta taagcatgta cgaatctctc cgcaattggc taaagggatc tcttgggtta
    22441 aggcctcgaa agaaacacct tatggcaaga ttcttgttca ttgggagaaa aaagagagta
    22501 gcttattgtt aaatgtaacg atccccgcca atagcgaggc gacaatcact ttgccaagcc
    22561 agacaaggca agtccgttta aatggcaaga cgctgacaaa cgctacctcg atacatatcc
    22621 cctccggcaa tcaccaaatc gtttcctcat tacctacgaa tcccgaaatt gaataatcat
    22681 aagttttgag cctatcgatt tgtcattccc tggtcgtaga gacacaatac actatgtctt
    22741 tacaaccggg gaagaatata gttccattat ttcttacagc ttacttttaa tgtccttatc
    22801 ccgtaacgag ggatagagag acgcattgaa ctggcgcctt tcttctcggt gacggttaag
    22861 tcctcaacca gacggttatc caattccacc aagctcgctt tcacgtcttg tccttggaag
    22921 gttatcgttt taggggaggc atcgctttgg gcattgaata ggcggatgta aaggtcatta
    22981 cctttataga ccatggagac caactcgtag gcattattct ctatccggaa aagggaaccg
    23041 gatgtcaagg tagcatcgcc acccaaggtt gcgaccaaag gctcattgcg tcgttcgctt
    23101 tgtgtccaaa tacggctttt ctcccaagtt ccggcatgag ggatcaaggc atacgagatc
    23161 tcggtcggac ggtctatgat ataatcccgg ccccacaagc ctttaccggc gtattgtacg
    23221 ttcaaggcca atgggaaatc cttaccatgc gcatagctgg tcgtatgatc cgtgaataat
    23281 gacagaccgc aagagttatc cttgctcgct acatccaccc aattcaaaat gatattatgc
    23341 ttgatgctat cccaacgatt gaaaaaggta ttctccaacc ggctctcgca aacatcgaac
    23401 ggagcgtcct tataaatctg ttggttggca atctgggtag gcagatacac caaaagtttg
    23461 taacggtcgt cataaaatgc cttacgggga ttatccgcac ggaattcgat acccggctca
    23521 ccaatgcgag ggtttcctgt ccaatccagt ttaacattca tatcgatgcg aggctctccc
    23581 tgcgttaacc ggatcgtttg ggtaaatgaa tactttccga tcttgccttt cacagctacc
    23641 ttcacgaata agggcccttg ctccaacacg ctcacctcag ccggttgatc catactggaa
    23701 aggaaaccgc cctcatcgat aaaatatccc cgaagctcat tgaacccacg ttcattccgg
    23761 ttatccacga attccttgcc tcgtacggct ttcgctttca agctttctat tacacctcct
    23821 ttagaggggt ttagcaccaa ggtgtataaa tcactttcca tgcgaaacgt accgtctttc
    23881 tgtctctcag ccttcaaggt tccagactgt ttatcctctg ccttccggat cgcataagag
    23941 gcataaccgg ctgaggggac ttgcgcacga aacaagagtt ttgaaatgcc gtcttccgtc
    24001 aaccattgag ccggttgttt ctttccttgc ttatcaagaa ccacccaatc cgagtttctc
    24061 catgagacgg gaacttccac cgccaccaat tcattccggt cggtagccaa ggtattatat
    24121 acgtacaccg tggattcacc ttccttttct ttcaataagg acaaggcgtt atcaattatc
    24181 tgacggctgt tttgattggt caccccagtc caatccgtaa ccgtctccgc ccatgtcttt
    24241 ttcccttgta gttgattgta aggaacgatc cagcaatcat gatgctgcga caataaaagc
    24301 gtgcgccatc cctcattgat acgttcggtc ggccattcca tgcctttgta taagcgagcg
    24361 taagccgcca ttttctccgc acgcacgata gcgttctcgg ctacccgtac ctctccggcc
    24421 aaacgctgca tgacctgcgt tccccacatc aagccaccta ggacatcctc ttgcgagaaa
    24481 taccaatcat cctgagtagt cccgacggag cagtcttgga tgtaattccg ccaagtctta
    24541 taggcggtcg gcgtataata gcccgtcgta tcctgtccca gccaagggcc tttatcccaa
    24601 ccatggctcc atgaggcatc ttggatacac atgccgaccg ggtgctggat gccggcatcc
    24661 aagcatttat ggatgtagtc ctccgtattg aaccacgaga tggactgcca acaagagccg
    24721 ggttgtaaat cctcgcaggc gtaacggggg acggtggtaa gtctcgtacc atccggccct
    24781 acccaattca ccaactcacc tccgtaggcg cttacgtagc caccccacat cgtattcggg
    24841 ttcttagtag aggcatacga gaagccgaat gacttcaata tataaggcag gcaactggta
    24901 aagcaaggct cctccgccga ataggtggtg aataccgcct cagggaaatg tttccggatt
    24961 agccgcattc catattcgaa ttggcggata gcgctctcgc ctgatgttcc gaagaaataa
    25021 ctttgggcat aggtcgggtt tacgtactcg atccgcccac tctccacgga ttgatcctta
    25081 aataagcgct tgaaagcctc gtaaccttca gggtctcgtt gccgtacgac ttcccatgat
    25141 tcaggctcga tctcgatatt gatattccag ttgggattct gccttaattt ctgggcgata
    25201 aaggcggtct gccccaccgg gtaatgcccg tagataccgc catgatagcc atcgatgaaa
    25261 taggcttgtt gggcatctgc ccaaccggcc aacaagaatt ggcttaatac gaatatcgct
    25321 agtttctttt tcatataaat atgtactatt aattcacatt tagaatactt ccagtcggtg
    25381 ggagacgggg cacgccccgt ctctacaagt ctgtaaattt cttgatctct attcgcaagg
    25441 ggattggttt attttgctca tagatctggt taaccagatc ctgttgctca ttcacgcaat
    25501 cctcacgaat ccccttgtgc atgtattgta gccaaaggtc gccgttccat tgcaagaaga
    25561 tgtcgtgggg acggtatttg cgcaaggtat ccacggcagc ctcgttgcag gcccaaagca
    25621 tgcccgtctt ccgcatcaag ttatattcca cccaataaaa ttcacgcatc ttacgctctt
    25681 tcaaccagcg ttcctcgttc atctggcgga tcttcatcgc ttgtttatac tgcggggtat
    25741 tctgaagaag agccatattg atacctcgct ccaactccct cgccgtaaaa cgaccgataa
    25801 actccccacc gatcgtcaac ccgtaatatc catccgacaa accgctcacg gacaatccct
    25861 cataattcat ctcatccata aaagggataa cactcaaggc atctgcctgc gtatgtttct
    25921 cattatcata ataagaggta tcgataggat acggaagcga tttcgcctcg tacgtaaaag
    25981 taaggttatc cgaggaaaca gacaaatccg agacacggca attatccgag cgagtcacct
    26041 ttttccccgc tccgtctatc cggatatcgg ctaccagctt accggccagg ccttgcgctt
    26101 tcaagaaaag ataagccatg accagatgtc cgtccgtaga gggatgtata cgatccttcc
    26161 cgcataaggt atacatggaa tccgccgctt gctcccattg gttgatcgct accatcgggc
    26221 gattgaaatc cacgaatccc cattgattct cccgggcacg ggcattcagg aaatccacga
    26281 tcttcaagat ctgcgtattc ttccccggga aagcgacctt attgaaacgg gaagtctcgt
    26341 cataaggaga acttccgatc aagattttcc tcacctccgg atacttctta tagacctcct
    26401 cgataagagc ataatcccga caagctttct ctacccggtt ccgagcgatc gtatcggccc
    26461 ccggcttccg aaaatccata tagccgacat cgttcatgcc aaaagatagc gtcaccactg
    26521 taggctcatg ttcgaaaacc ttatccaacc gctggtaaat catctcggct acatccccac
    26581 ctactccctc gttaaagata tcgatgcgtt gatccgggaa acgggtcata tagtacagcc
    26641 agatatatga atgataatga ccaccgcaag taatgctgtt tcccacgaag gcgatccgat
    26701 ctcctttctg aaacggagct atcgactgag catatactct tgcaagacct gataaaagca
    26761 aacagacaaa caaaacatat cttttcatct ctatttctct cttctctaat tttctgtgat
    26821 gaataatata taccgtgtta aaaaatatta ctatcaatag taatcgtatt tatcatggat
    26881 aataatccgg attactacgg atagtaatat cctcccacac acctctagtc tagagaatcg
    26941 cccgcttact tttagcgaac gacatcctca ccgagcagag ggttcagttc tttctcacgc
    27001 aaaggtaccg ggaaaaccaa atccgattct ttaaacggat acgtatgatt aaccgcctga
    27061 tagccgaata aatcaaccat ttgcttcgat accggatcaa acgcacggtg agtacgcaac
    27121 atatcatacc atcctgtaaa ctcataacag agttcccacg cacgctcttt caatacttga
    27181 tcaaccgtga tcgaagttgg tctcgcctca tcaggtaacg cacggtgacg aacttggaaa
    27241 taagcatcaa ccgccgtagc gtcagaagta gatcctccat ccaaggtagc ttttgcctcc
    27301 gcacacatta atagaacatc cgcataacgg taaaccggga tattcgcccc gctctttcct
    27361 gtagattccg cattctcatc ccaatatttg catagataag gaacatccaa agtaatcgtt
    27421 gtctccggat caccatattt gggtttagaa gtatagaaaa actcctcatt ccgtttacga
    27481 atatcttggt catcataact ttcataaaac tctttacgag gagccaaacc acccccataa
    27541 gccggagtaa tggaaatcgg ttgttccgga taaggcaaaa ggccaaaatg gaaaggagcc
    27601 ccggcatctt gcgcctcacg ctggatcata aaaatatgct caccactatt ttcgttctct
    27661 aacgcacgta aatccttata atcagcgaac aagctaaagg ctccactgtc aataacctcc
    27721 ttggctttct cgtaagccaa ttgataatac tcatttcctt tttgaagcgg ataacctgcc
    27781 attgtcaaat aaaccttggc taaaagggtt ttgatcgctc ccatagagac atggcctgtt
    27841 ttatcactcc aatccaaacc ggactgctcc gcctttttca agtcttccac gatctggtta
    27901 taaatatctt ccttaggaga ccttggaatc ttcaccgtat tcaagtctac cgtaggttcc
    27961 gtcttcaacg ggatatcccc gaataattgt accccttgaa aatagtaata cgcccgcaag
    28021 aaataagcct ctcccagata cttcgctttc tggctctcgc taataatatc cgtagcggaa
    28081 acattttgaa tcacgctatt acaattttcc aaaggaaaga aagtagcctt ccagaagtta
    28141 cgaataatgc cgttactctc ttccaaaccg gaaagcaaca agaactggtt ctgctcatta
    28201 ccggccgcac gaggacgata actagtacct acaagatatt ccaagttaaa aaggtgaact
    28261 gtggcaatct cgaggtcgga actcaacaga tcatcaagcc cgtcataagt gccatccaca
    28321 gccgccttta tctggttctc tgtcgtataa tattcagaag gactcaagaa ggttttcggg
    28381 tcttcctcta aaaaattcgt acaggatgta aaagccattg tcgccgaaag caagccacac
    28441 atccatacat gcgctttatt tttcatatct tagtttttta cgaagtaaag attaaacaat
    28501 tagaaattaa cacctaaagt aaatgaatac gtacgaggtt tgggataggt ataaaaatcc
    28561 actccttgct caaatacagc atcataactc gtcacctccg gatcactacc agaatagttc
    28621 gtaatcaaga acgcattctc cacattgaat cccaaggata aactcttgat gtgagcggca
    28681 gaaagcatac gggaactaaa gtcatatttc aagccgatat tacgtaaacg caagaacgaa
    28741 cccggctcac aactccaaga atctacgtca ttctcatatc catctcccgg aaggcgcaag
    28801 ctaggcacca tcgtgttttg gttttccggc gtccaagcgt tcaccggaat gtccgcataa
    28861 gcattggaga atgtcacacg gttacccatc aactggcgag tgaagttaat caacttatta
    28921 ccatacaccc attgtaaatc aaacataaac gtgaagcctt tccacgagaa tgtatttgtc
    28981 atattcatct cgaatttagg agcgccattt ccgatatagt cttggtcttc accatccttc
    29041 attccattac catttttgtc ccaatacttg atatcgccgg gtttcttatt atatttagcg
    29101 gcttcttccg cctcatcggt tccccatgta cctaggcgaa catagccgta aagggcattt
    29161 aaaggatgtc cctcttcaat acgtcctccc catttaccaa tgatattatc atttatatcc
    29221 agtaccatcg atcggttcat cgtataattc caagaggtag tccataagaa atcacggctt
    29281 tggatattgc gtgtattcaa gctcatctca agaccttgat tacggatctt acccagattt
    29341 gtcatagttt tctcatatcc cgagttagaa ggcaattgta gctcatacaa taaatcagtc
    29401 gtaatcttat gataataatc cgccataaac tcgatacgcc cattaaagaa actcaaatcg
    29461 atacccgcat caagttgtct ggatttctcc cagcgtaaat ccggatttgc catacttttc
    29521 aacgtaacga tcgtcgtcat atccttgcca aaaggaaggc gtttattctc ataacgtgcc
    29581 atagacgcat aatcaccgat ttccgcgtta cccaccgtac cgtagctcaa acggactttc
    29641 atatcatcaa tcaccttttt tgcgttctcg aagaaattct cattggatac acgccaagcg
    29701 gccgagaatg aaggaaagaa accatattgg ttattcaagc caaaacgaga agaaccatcc
    29761 tcacggaaag aagcgcccaa taagtaacga ttgtcaaaat tatagttgat acgggcatag
    29821 taagaattca ttttattatc cgtatagtct gagccaacct tagaacgtac ggtgccgact
    29881 cccatattat tgtactcaaa ataatcatcg aagaaattct cggcccctag ctcgcttttc
    29941 tctgtttttg agtaatacca actggctccc gctacgacat tcaagttatg cttattccag
    30001 cttttatcaa aagtcaagta gtcctcattc gtccacgaca tcgtatttcg atgtgctttc
    30061 tccgctttac ccttttgagt atctccatag ccgaataagg tactcgggtt ataagatgaa
    30121 ttgatataag aaccatcctg gcggctgaag ctagtcgtta actttaacca agaggtaatc
    30181 ttaaacgtac caatcacgtt agccaacgtg tactgattct tatcgatatt cttacgttcc
    30241 tttaaaatcc tcacgggatt ctccgtatct tccgcacctg gataatctcc tttacgggaa
    30301 taggtaccat cctcatattg aaccggaagg aacggtaatg cttccaatgt ataccgagag
    30361 atcgcattct ccgagtttcg ggcattacta gatccaacat tcaacatggc ctgtaaatgg
    30421 aaccattctt tcaaatccca tccgacattg ataaatgcgt ttaactgacg tttataggtc
    30481 tccaacatta taccttgatt atctttgtaa cttacattcg ccacagcggt cagcttatcg
    30541 cttcctccag agaaactaag tgaatgctga tgagaaaaag ccgtacgagt cacggcatcc
    30601 tgccaatccg tatcatattt cggagtcccg tccggattga acaggtcatt cttatgcgta
    30661 aacatattgc tcggatccag atggggagcg atacgtcccg gttgagcctc ataagcacgc
    30721 ttgaatacat ccaaagcctc ttccgcattt aagacatcga ctttacgagc taacgttcct
    30781 gctgacagaa ctgtattata cgagatattc gtcgtatttt tcttaccttc ctttgttgtt
    30841 atcaccacaa cgccattcgc acctctcgca ccataaatag aagaggaagt agcgtctttc
    30901 aagatatcga tagactggac aatattcgga tcaatctggt ccggatccac gccaaccaca
    30961 ccatcgacca catatagcgg tgtattagaa gaattcaaag aaccgatacc acggattttt
    31021 atcgcaggac taccacccgg cgcaccagaa ttcaaggcga tattaacacc agccaccttt
    31081 ccggccaatc cttggaatac gttcgtggca ttcggacgct ccaataactt ctccgagtct
    31141 acggaaccca ctgatgttga caagtttcgt ttcaacatcg taccatatcc aacgacaacg
    31201 acctcttcaa gcgccttata atcctcggcc aacttcacgt taaacagtgt acgattcccg
    31261 acctcgatct cttgctccgc atagccgata taggaaaatg acaggatatc gttattagcc
    31321 gcatccaagc taaactttcc atccagatcc gtaaccgtac cgaccgtcgt accctttatc
    31381 acgacattgg ccccgataac cggtatgcca tccggatccg taacgatacc ggagatcttt
    31441 ttcttttgtt gctgtacggc gtctttcttc aagatcgtga tgtgcttacc tgatatgcgg
    31501 taggtcaagt tcgtgttttt caacaactca ttcaacacgt cggtgacttg gcgattcttc
    31561 acctgtatat ccacctgctt actattatcg atatcctcgc tcttatagaa aaacatgaac
    31621 tcggtctgtt tctcaatctc cgagacgaca tcatagaacg tcccgttctt tacttctacc
    31681 gtaacttgag ctttttgcgc ataggtatcc gccgagacat gcaatatacc cagtattaaa
    31741 aaaagcaatg tgatcttcat gattgattta atttttttag gcaatagctc atcgctattc
    31801 cagacttttt ccataagttt gtaattattt tttattaatg acttaccttg ctcgctactt
    31861 tttagaggac agcgataaag gtgattaaac gaataatgaa cgtctaagaa tcgggggtga
    31921 gtggtgtcag tcccgattct tttttgtgat caggtatttg tcataggcaa ttcgaatgtt
    31981 taaggttata catctattat tttgttattt gctcctcgcc gatatcagga tatcttttcc
    32041 gtctttcgtg aaagtgaatt gtttctccga gttaataata tctagcacct cttgtatacc
    32101 ttgatccaag gagaaggttc ctgtgtagcg gatgttccgc agactgtcat gcgccaagcg
    32161 gatatttacc ccatagtaat tctccagacg ttttacgata gagactaagg tctcatcctt
    32221 gaaacgatat ttccctccta cccaagcgtt cgagatcgag gcatctgtct ctgacaagaa
    32281 aatagagccg gtccggttat ccgaccgggc ttgttgattc ggctttagct tcatgctact
    32341 cattttccgt ccttgagcgt caaaagattc caacaggata ctaccactta ataaggtggt
    32401 gacgctaaag cgatcatcgt tgaaagcctg tatattgaat gaggttccga gtaccgtgat
    32461 ttgttggttc tttagtttta cgatgaaagg tttcgaatga ttcttcgcaa cctcgaaata
    32521 ggcctcaccc tccagatgaa ccacacgctc atctccatta aaagaggtgg ggtatttaaa
    32581 acgggtggag gcattgagta tgatcttact gccgtcggat agcaatagcg tgttcgcacg
    32641 tccgcctttt tccactacga tctcgttata ttccatatcg ccggcatata aacgattgct
    32701 tatccattga ttcataccca cacctattcc catagcgatt acgataatcg ccgcatatct
    32761 caagaatgaa agccagaact gtttgccaag gaccttggat ttcacagata cgccagagat
    32821 cgcatccagc tttccagcca ttcgctccca actacgctcc acggaataat ggttcaagaa
    32881 cgccacttct ttccgagtgt caaaaagccc cttaagctca aagaagtggg ctttattagc
    32941 gtcactctca tgaatccaag catccaacac tcgaagttca tcctcttgaa tctcgttctg
    33001 caaatagcgt atgatcagtt cttctatcga attattagat tccattttct gtttcattta
    33061 taatatatac gaccggtttc ctctttttac ttacgtattc taccgtattt tcatctaaaa
    33121 aataaaacca gtgccagaag cgccaacaca ttccgtatga tcttcaatcc tttatagagt
    33181 tgcgcctcta ccgtacgttg agagatattt agcattcctg cgatctccac tgatttcttc
    33241 ccgtccacat aagccaacgt aaaaacctct cggcatctgt ccggtaactt ggctatttcc
    33301 cggtaaacgg agtccagacg ctctttctcc agctccgccg catccgactg attataataa
    33361 tctatctcct ctatctttag tctacgagca acctcatccg cataagtcat ttctattgat
    33421 ttatgcttta ggtaatcgag gcaagcattt tgaacggaac ggaataggta tgtcttcaag
    33481 ccttcttcca cggaataaat ctctttcttt tgccagatct tgatgaatat atcatgcact
    33541 aaatcttccg ccgtatcgct atccacatat ttcgaggcat aaaagatcag tctgggggca
    33601 ttctccagat ataataattt aaatttatcc aactcatggt tcttaataat atagtctttc
    33661 atgctcaatg tggacatttc ttgtattata ttagacagtt caaggcttct cctttatcta
    33721 tatacgatca tagaaacaga tctacttacg cccacacgaa aaaaataaca caaaaacaaa
    33781 aagccctatc cgaacttaat cagatagggc tttcagatta ttctatcgct agatattatc
    33841 tcaacgggat atattgtaca aacgcctcga tcgcctcata agaagccaaa cctaattggc
    33901 gatacaactc tgcggtagca cggttgcgat cttcggcacg ctgccagaac aaacgctcgt
    33961 cgtcacccag atacggagcg ctctcggcct gcgattgatg cttcaaaata gcgttacgtt
    34021 tgaagcgcaa ctcctccgga ctgataggta cggccatctc aatatggtcc atttcccatt
    34081 ctgcccatgc gccgcgatac atccatacac ggcagttctt catccattcc tcgtctttca
    34141 cctcgtcgat agcggccagt acggcatcca gacaaacctt gtgggttccg tgcgggtcag
    34201 ccaagtcacc ggcgacaaac atttgatccg gcttgatctc gagcaacagg gcctttacga
    34261 tatccttgtc gacctcactc aaatcattct ttttcactaa tccggtctcg tagaacggaa
    34321 gatccaagaa atgaacatga tcgtccttca cgcccgagta gcggcaaccg tgacgggcct
    34381 cctcccgacg gatcgttcct ttcataaaga ggacatcctt ccgctccggc tcgccgttct
    34441 ccaccttctc gtaacgcagg tagttgatga tctcgttcgc cttatccttc acggccgagt
    34501 cgggagagta tttctcacat acatcacgca aatactcgca ataacggatt acctcctcgt
    34561 cgcctacggc aatattaccg gaagtctcgt aagccacatg cacatcatga tgctggtcgc
    34621 acaaacgacg caaggttccg cccatggaga tcacgtcatc atccgggtgc ggactgaata
    34681 cgatcacttt cttcggatac gggttagcac gctccggacg attggaatcg tcggcgttcg
    34741 gcttgccacc cggccatccg gtaatcgtat gctggatatc gttgaatatc ttgatattta
    34801 cgttgtaagc ggaaccatat aacgccaata gctcacccaa tccgtgctcg ctataatcct
    34861 tgtttgtcaa tttcaagatc ggtttgtccg tcaactgaca caaccaaacg atcgcacggc
    34921 ggatcaactt attatcccac tcgcagctag tcaccaacca aggatgactg atacgagtca
    34981 agtcataagc ggcggaaaga tcgatcacga ccttggcgtt cggatgattc tgcaaatagc
    35041 tggaaggaac ggcatcgcta accttgccct caacggtctt agcgacaatg ctagccttat
    35101 cctcgcccca agccatcaag atcacgctgc gggcgttcat catcgtagag atacccatcg
    35161 tgatgatacc tgccgggaca ttctcctgcg aagggaacgt acgggcagcc tctttgcggg
    35221 aagcgccttc caacaagacc atacgggtac gcgagctgat cgtcgttcca cccacgttga
    35281 acatgatatt gctggagtta ccgataccta gcaacatgca atcgatacct cccacggatt
    35341 ggatcgtctc ctcatactgg cgacagaaat ctaggatagc gtctttcggc atgcttccgt
    35401 ccgggcaata gatattcgca ggatcgatat cgacctgatc gaataactcc tcttttaggc
    35461 gagccagatt tccggcgctg ggattagcca atggatagaa ctcatattcc acgaaagcaa
    35521 tcacattgcg gaaacttaat ttctcctctt tatgcatacg gatcaactcc ttgtaaacgc
    35581 ttagcggaga acgtccgccg ggtaaagcga tcacgaaggg cttaccaata tcttgttttt
    35641 tacggatttg tgttgctatc tctttagcga tagcgaaaga accttcctcg gccgattcgt
    35701 aaatgtttgt cggaatcttt tccaaacgag ttaaaactga atgctcgaaa gcattttccg
    35761 ggcgataata ccgcaacggt atatgcgtca gagtaatttg agaactaagg ttcgttttca
    35821 tgtttaatta ttgatttagt attacaatct tacttgaatc acaaatatat gaaataagta
    35881 ctgatttcgc catacgttga tagaacaaat ttattagccg aaaggtttga tctatatcgc
    35941 ctaaaaataa aaaaggaccg tcccggccag ccaagacagc ccctctcttt attattaacg
    36001 tgtttagacc aatgtatttg tctccggaac taagtttccc atgctccata ccgcacgcac
    36061 gttcaactta cgatccaaga tcacgatatc cgcatccttc cctctttgca aggttccggt
    36121 gcgatcgctt acccccatca ggcgggccgg agtctcggaa gccatacgga ctgcatcggc
    36181 caaaggaatg tcagccttct gcaccatcgt acgtaccagt acgtccatcg tggcgatact
    36241 tcccaccaat gaagaatgat ccgccaactt gcatacgcca tcctcaatga taatgcgggg
    36301 atcggataac ggcttaccct cgttggctgc gcatgagaga gcgtccgtaa ccaagcaagt
    36361 acgttccact cctttcaact tatagaccaa tcggaggatc gtagagggta aatgacgccc
    36421 gtcagcaatc acctctaccg tcatatcgtc catcaagaaa acactttcca ccgttccctc
    36481 gtacttatat tcacgacgct tatggaaacc aggcatggcg ttatagaaat gagccgcatg
    36541 cgtgaaaccg gcattgtaag cggtcttaat atcatcaaac tccgcttccg tatgcgagat
    36601 agcggatagg attcccctcg acttcaagta ttgggcgaac tcaagcgcac ccggtatctc
    36661 cgggctggaa tcccagcgct tgatgcaatc cgtgcgttcc aatatctctt tatattcttt
    36721 cgggtcggcg ggattctcct tatcgataaa caggctcgcc gccatcttcg gattcagata
    36781 cggtccctcg atatgcaatc ccaagatagg gccgtctttt ttcctcatca tctcctcgca
    36841 tacggccacc gccttatcga tcaccccgat ttccggagcc aacacggtag ggaatatcgt
    36901 cgtggcccca tgcttctgat gggcagctac cgcaccgtgg aaagcctctt ccgtacattc
    36961 ggagaagtcg aagcccccac cgccatggat attcatcgcc acgaaaccgg gaacgatcga
    37021 cattcctttc gcatccacca ccttggcgcc aatcaccgct aaatcgctat ttgtaacctc
    37081 caatatcttc ccgtcgctaa tcaatacgga accatccttc atccatcctt gcggcgtaag
    37141 gatatggcca tttataatct gtgtcaacat aatcgttctt gcttagaata gtttattcgt
    37201 accttcaacc aacttaccca tcgcccagac cgcacggaca ttcaagtcac ggtccaacaa
    37261 gacgatatcg gcgtctttgc cccgctgcaa cgttcccttg cgatcggata cgcccatgat
    37321 acgggcggga gtctccgagg ccatacgcac ggcatcctcc aaggggatct cggccttctg
    37381 caccatcgta cggatcaggc ggtccatcgt ggcgacacta cccgccaagg ccgagcggtc
    37441 ggccaactta cacacgccat cctcgatgat gacacgggga tcgaaagcga cttggctatc
    37501 actggcagcg caagccaagg catccgtgat cagacaagtg cgttccacac cttttatctt
    37561 atagaccaga cgaaggatcg taggcggcac atggatacca tcggccacga cctcgacggt
    37621 catatcatcg agcagataga tactttccac cgttccctca tacttatact cgcggcgttt
    37681 atggaagccc ggcatggcgt tatagaaatg ggtggcgtgg gtataaccta cctcataagc
    37741 ggtcaggata tcctcaaact cggcttgggt atgccctacc gaggcgagca cgcctttcga
    37801 ggtgatatat ttaccaaact gcatcgctcc cggaagttcc ggagcggcat cccagcgctt
    37861 gatacaatgc gtttcctcca gcaaagggat atattcctcg ggatcgggat tcttgatgtt
    37921 ctcagggatt tgtccaccag ccattttcat attgaaataa tgtccttcta agtgaagccc
    37981 cagaaccggg ctatctttct cggccatcag tttctcggtg gtctcggcgg cggcacggat
    38041 catcgggatg gtagaagagg ataaggtggg gaagatactg gtagtaccgt gtttcatgtg
    38101 tgtggccacc gccgcacgga aagcttcctc ggtgccttcc ataaaatcac ggcctccacc
    38161 tccgtgcacg tgaatttcca cgcctccggg gacgatgtac atacctttgg cgtctatcaa
    38221 ggttgccccc actaccgcta agtcgcagtt tgtcacttct aaaatcttcc cgtcgcttat
    38281 caataccgag ccgtctttca gccagccttg cggggtaaga atctttccat taatgatctg
    38341 tgttaacatg atatgtgttt taagctttcg cgtttctttg gatagcaaag ttaaggactt
    38401 tctttttaaa acgagtaagc tattagaggt tattttcaaa gaataatcaa aatgacactt
    38461 tgtaatccga acctccggag aatcgaatat tccgggccta agtacagctc gcctctaaat
    38521 ccgaaagaaa atttcagtaa tcaactaatg gccaacacca taccccaaaa cagcctttta
    38581 ttctagcgaa atcaattcat cctaattcat atcaaaggga gagattggta tcattgatag
    38641 ggttacaata gggttctagc agggtaagaa tgcctattca cgagtagtca taaccctatt
    38701 cttgagtagt cacaatgccc aacggcggca tatgcgtcgg ccgatggcag tactggcgta
    38761 gcccaatgcg gcctatcacg catgggaaaa gggatattct cccttttaaa agccagctct
    38821 cgcactctct cttccgctat ttcgcatcat caacggcaag cacttgtcac gaaaacagga
    38881 gtatttgaat caaaaagatc agataagctg cctttcactg gctagcagcc ttttcatgaa
    38941 tcctgcgtat tcaactcttc caactccatt gtccgttcgg tccatagatc catcgcatcg
    39001 gaaagttctt tttttagggc agaatattca ccgtagagag aagcgtcgga ggcaccttcc
    39061 ggcgtagcca gcttcgcctc gataacggca atgccattct caagctccga gatacgggcc
    39121 tcggcctcgg caacagcttt ctccgctttc ttaatcactt tactcagttc cttccttgcc
    39181 tcataggaga gcttgttatg ggatacctga gcctcaccgg taccggacat ggaagtactc
    39241 gtcccagtag aacgttccaa ttcacgcaag ctatccattt tcttatgctc caagaaatta
    39301 tagatgccgc ctaaatgctc gacgactttc tggttaccga actcatagac cttatcgact
    39361 aggccatcca agaactcacg gtcgtgggaa accacgatca ccgtgccgtc gaactccctc
    39421 aaggcgtctt tcagcacgtc tttcgaacgc atatccaagt ggttcgtcgg ctcatcgaga
    39481 atcagcaggt tgaccggctc caataacaag cggatcatcg ccaaacgggt acgctcgcca
    39541 cccgacagga ctttcacctt cttatcggag gcctcgccgc caaacatgaa agcacctagg
    39601 atatcccgta tcttcaaacg gatatcccct tgggctacgt aatcgatcgt atcgaaaacg
    39661 gtaaggttct cgttcaatag ctgcgcttgg ttctgggcga agtaaccgat cttcacgtta
    39721 tggcctaatt ggagctttcc ggtgaaatcg gtaatctctc ccatgataca tttcaccaag
    39781 gtagatttac cctcaccgtt ctttccgaca aaagcgactt tatcaccccg gttgatcgta
    39841 agcgtcacat gatcgaagat cagatgatcg ccataacgct tcgccacctc ctcgcagatc
    39901 accggataag aaccggaacg gggagcgggc ggaaatttca gccgcaacat ggctgtatcc
    39961 acatcgtcta cctcgatacg ttccactttt tccaattgtt tgatgcggga ttgtacctgt
    40021 acggacttcg tggctttata acgaaaacgc tcgataaacg cctcggtatc ggccaatttc
    40081 ttctgttggt tctcataagc gcgctgctgc tgctcacggc gttcacggcg aagtacgacg
    40141 tactccgaat attttacctt ataatcgtag accttaccta gttcgatctc caaggtccgg
    40201 aaagtcgtat tatcgataaa ggcacggtcg tgcgacacta agatcacagc gttggcacgg
    40261 gtagcgataa agttctccaa ccattggatg gactcgatat ccagatggtt cgtcggctca
    40321 tccagcagca acacgtccgg cctacggagt aagagcttcg ccaactcgat acgcatgcgc
    40381 cagcctccgc tgaactcaga cgtcgggcgg tcgaaatcgc tacggctaaa acctagtccg
    40441 gccaatgtac gctccaactc cgcatggtag ttgtttcctc ccatcatctg gaaatgctcc
    40501 gatagatacg tgacacgatc aatcagcttt tgatagccct cggagtcata atccgtacgc
    40561 tccgccaatt gagtattcaa gcgattgatc tcctcctcca tctcatggat atgctcgaaa
    40621 gcgcattccg cctcctcccg aaccgtacgg gtatccacca attgcatgtg ctggggcagg
    40681 tatccgatcg tgacctcctt cggtacgcta acagttccag aagtcggcga ttgcaggcct
    40741 gcgaatattt tcaacattgt agatttgccc gctccgttct tgcccaccaa agcgatacgg
    40801 tccttcttgt ttaccacaaa agaaatatca tcaaaaagcg taaaaccgcc aaactccact
    40861 gttagtcctt caaccgaaat catactgtct ctttaattta tgaccgcaaa gatacaacag
    40921 ttcaaggttt actcacaaac ttttcaatta atatcagcac atccttatgc aacggaaggg
    40981 ccggatcggt ataggtagcc atctgttttt gctgatccat cgtatcgcaa gtcttcatca
    41041 gatggttcat attcccgatc aaatggtaat cggccgaagg ttgggatcgc ttcaatagtt
    41101 cggcgtcttt tacggatact tgcatatcct tatccccttg caagatcaac accgggactt
    41161 ttagtttctt gatgatttcc tgcggattat acgtatacca tgagatcata taaggctgta
    41221 ccgacgagcg gaacagggct tgcaaaccga tcggcacgtc cggtacgagc ttcccttcct
    41281 tcaaggacgt gtttatggat ctcaccatat tccggatcac ttccggttga ccggccatct
    41341 gttcctctat gatctcataa gcgggacgcc ccgcacccgc caccgaaatg tatcctttca
    41401 ctttcggatt atccaccgaa gccgccatac cgaccaacgc tccctcgcta tgccccaaca
    41461 catagattcc ggagatccgt ttgtccttgc ttaaataatc gatccagcct cgtgcgtcct
    41521 tgatcccgtc ctcgaaacgc atggaatact catcctttcc ggccgaggc
//
LOCUS       DBMDTB010000026        39505 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_406_length_39505_cov_13.317937, whole genome shotgun sequence.
ACCESSION   DBMDTB010000026 DBMDTB010000000
VERSION     DBMDTB010000026.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 39505)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 39505)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39505
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_406_length_39505_cov_13.317937"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(141..680)
                     /locus_tag="ACZPB4_06235"
     CDS             complement(141..680)
                     /locus_tag="ACZPB4_06235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma-70 factor"
                     /protein_id="HIR1097853.1"
                     /translation="MQWVCEIALSDSQTAFKSLYLAYFQRLMRFTSLYVPSSVEAEEI
                     VSDTFLSLWNNRKSLPEISNFDSYIYGIARHKAISLYRTQHMEKVQIDENTIDLFAHT
                     DTTPEEELISKECIDHLNEAINTLPDKCKMAFKLIREDKMKYKDAANILEISVKTLEA
                     HIATAVRKLRESLAKEIND"
     gene            938..3193
                     /locus_tag="ACZPB4_06240"
     CDS             938..3193
                     /locus_tag="ACZPB4_06240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anion permease"
                     /protein_id="HIR1097854.1"
                     /translation="METFYLFLVIFLFVLAIVDLSVGVSNDAVNFLNSAIGARAASFK
                     VIIAIAAVGVFVGAALSNGMMDIARHGIYQPQHFYFSEIMCILAAVMLTDVVLLDIFN
                     SLGMPTSTTVSMVFELVGGTVAIALVKIASSSGALQLGDLLNTEKAFTVILGIFLSVA
                     IAFFFGVIVQYLSRILFSFNYKKSSKYFIGLFGGLAATSIIYFMLIKGLKTSSFMTGE
                     FKDMVYANTGMIVLGCMVFFTILMQVLHWLKVNVFKVVILMGTFALALAFAGNDLVNF
                     IGVPLAGYSSYMDLMAQGGTTTTDTFLMTSLLGPAQTPWYFLVGSGIVMVIALATSKK
                     AQNVVKTSLDLSRQSDGEESFGTSPVARVLVRNCSNISATILSIVPTPVKNWIDSRFD
                     QSEMIMDDKASFDLVRASVNVVLSGLLIALGTSLKLPLSTTYVAFMVAMGTSLADRAW
                     GRESAVYRITGVLSVIGGWFITAGAAFTICFIVALLIYWGGIPALVAMIGLAIYSLVR
                     SHFAYKAKLRKEALKEEVNSTVSKLRKATDTREALALFREHSREELQSDLDFTAEVFG
                     KAVNGFMNENLRELRKVLTAVEEKKIHLKQVKRVGTLGVTQLDHDIAVEKGLYYYQGN
                     DFASEIIFSIRRLAEPMKDHIDNNFSPLSPVQKDDFGKVSEQIISFLRNCATMIRKND
                     YIGFEELIAESITLMNQLTALKKGELKRIQGQSGSTKVSMVYLNMVQEAQNVVSFTAN
                     LLKVSRKFQKE"
     gene            complement(3250..4122)
                     /locus_tag="ACZPB4_06245"
     CDS             complement(3250..4122)
                     /locus_tag="ACZPB4_06245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097855.1"
                     /translation="MNNLQEFYRKIEYLRSNGVKMKEIADWIDMAPSILSSLYTTVLP
                     NYFEGIKSYPPEEALDSALALVNNVSKKRLLSHIEEMILRLDQMEFAEPDSLKDNPFA
                     KQLMEETRLSASKIEAFKGIYTSYSLSSSSDCLKMEPFLLSPSDNQVRVGRISAYGEA
                     QWGFGIMPDPQNFHCMLNENQAPQFTMVTIYLQIPFFKNPRQLRGLYIGQDYNRNPIA
                     RRILLIKESESTEIDEFMSRKSGLIDKEDFTPEQQVYYDYTCQTGDFIKMCTVPSLRM
                     DESDLVKEKKMLTL"
     gene            4319..5662
                     /locus_tag="ACZPB4_06250"
     CDS             4319..5662
                     /locus_tag="ACZPB4_06250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5690 family protein"
                     /protein_id="HIR1097856.1"
                     /translation="MDTAIQSNKTSRKRISDLLFILWAGGAALLSYSLVYMLRKPYTA
                     AAFEDLEVFNMDYKVAVTIVQILGYVVSKFMGIKLISELRREERLRFILMSVVMAELS
                     LVFFGLLSAPYNIAAMFLNGLSLGCMWGIIFSFIEGRRMTDVLASLLGVSMVISSGTA
                     KSVGLYVMDIWQVSEFWMPALIGAVALPLLALLGYALNRLPQPTEEDIALKSERETLN
                     GRQRWELFKHFMPFLTMLFVANIAIVVLRDIKEDFLVNIIDMSGYSPWLFTQIDSVVT
                     LTILAIFGLMVLVKDNFKALSVLYGLIITGMMVMAFVSFGQERMGLSPVTWLFLQSLC
                     LYMAYLTFQTIFFDRFIACFKIRGNVGFFIVLTDFLGYTGTILVLVLKEFVGTGLDWE
                     VFYNQLAGYVGIFCCATFVASFVYLRQRYRKETALCGCEEIATLEPTENNVLTIA"
     gene            5697..6485
                     /gene="phnX"
                     /locus_tag="ACZPB4_06255"
     CDS             5697..6485
                     /gene="phnX"
                     /locus_tag="ACZPB4_06255"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050194 - phosphonoacetaldehyde hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0019700 - organic phosphonate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HIR1097857.1"
                     /translation="MKKISGVIMDWAGTAVDYGCFAPLNAFLKVFSEEKGIDITYRQA
                     REPMGLLKIDHIKAILSMPEVNEKFRALYKRDWNKGDVDEMYASFEKHLFASLKDFTT
                     PIPGVLETMAMLREQGIKIGSTTGYTAKMMEIVRPGAEARGYRVDNLVTPNEVPAGRP
                     APYMIYKNMIDLAIPSVDQVVKVGDTIADIKEGVNAKVWSVGIVTGSNEMGVSEEEYN
                     SRPAEEWESLKKEVRERMLAAGAHFVLDTIAELPACIEKINNRN"
     gene            6517..7602
                     /gene="phnW"
                     /locus_tag="ACZPB4_06260"
     CDS             6517..7602
                     /gene="phnW"
                     /locus_tag="ACZPB4_06260"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047304 - 2-aminoethylphosphonate-pyruvate
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0019700 - organic phosphonate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HIR1097858.1"
                     /translation="MRNYLLLTPGPLSTSQTVREAMLQDWCTWDKDYNEGIVTPIRKG
                     LLAIAGLDGDAYTSVLLQGSGTYCVEATIGATVRPEDKLLILANGAYGKRMAQIADYY
                     HINYVLVSLHETELVTGEVARRALEEHPGITHLSMVHSETTTGLLNPIEEVAEVIKGR
                     GITFIVDAMSSFGGVPIDVKGLGIDFLVSSANKCIQGVPGFGFILAQKDKLMATKGNA
                     RSLSLDIYAQWEAMEKGGGKWRFTSPTHVVHAFYQAMKELNEEGGITARYKRYQENHQ
                     ILVEGMRGLGFKTLLPDDAQGPIITSFLYPSADFDFTSFYARLKEKGFVIYPGKISDA
                     DTFRIGNIGDIFPKDMEALIQSIKEIR"
     gene            complement(7586..8215)
                     /locus_tag="ACZPB4_06265"
     CDS             complement(7586..8215)
                     /locus_tag="ACZPB4_06265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WbqC family protein"
                     /protein_id="HIR1097859.1"
                     /translation="MRPVYIATAYLGPIQQYCKMLQYPEVRIETAENYVKQTYRNRCS
                     IAAANGPLSLSIPIVKPDTLKCQTKDIRISDHGNWRHLHWNALVSAYNMSPFFEYYAD
                     DFAPFYEKKYEFLLDFNEELRRLVCDLLDMQPAVVYTEHYEPEVANDFRETIRPKHEG
                     EDPAFRPEPYYQVFREKFGFLPNLSIADLLFNMGPEGLVTLRASITGSL"
     gene            complement(8218..9078)
                     /gene="lepB"
                     /locus_tag="ACZPB4_06270"
     CDS             complement(8218..9078)
                     /gene="lepB"
                     /locus_tag="ACZPB4_06270"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HIR1097860.1"
                     /translation="MTIQRFLIVLMKWLAAFALAAGIVMLIRLFCIESYRISTDSMEE
                     ALHKGDYILVNKIPGKNKPVRGKVVLFTSPLSRDSADAPLFISRCIGMPGDTIRVSMD
                     GYTINGQKIPRSPRSLCSYFITLSAKETFLETLEKLDIPLRDFRQESFGCMLSLTAFE
                     EYQLREELPDAINRHFIGEQMQEYMLIVPRKDRAYPLDAASLTACKEIIMRETDGKAS
                     FRDGKLYLDGRETNFFFFQQDYYWVLSDNTNEAVDSRHLGFIPADHIVGNAWLCWYSP
                     DKQRIFKPVH"
     gene            complement(9098..10495)
                     /locus_tag="ACZPB4_06275"
     CDS             complement(9098..10495)
                     /locus_tag="ACZPB4_06275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S26 family signal peptidase"
                     /protein_id="HIR1097861.1"
                     /translation="MKKFTKKQWIKFSIAAVLYTLFAIWMQNLWLLLGLIVLVDIFLT
                     HYIPWGAWKRSKNPAVRNVLEWVDDIVFALVAVYFINLFVFQNYQIPSSSLEKSLLVG
                     DYLFVSKLSYGPRVPNTPISFPLVQNTLPILNCKSYLDWPEWGYKRVKGLGHVKRNDI
                     VVFNFPAGDTIAVKVQNPDYYSLVEEYGRERILLDKATFGEVMYRPVDKRENYVKRCI
                     GMPGDTLQLIDNQVYIDGKPAENPKDMQFNYFIETDGSPITEEQFRLMDVSKDDRMLA
                     SSGGYYQNLLSYLGFTPNANGQYNPVYRLPLTKKALAIAEKLPTVKKVIIEPETLGGP
                     TYPVGYNTGWTRDNFGPLWIPKKGATIPLDERNLALYSRCIKNYENNTLEVKDGKVYI
                     NGKPETSYTFKYDYYWMMGDNRHNSADSRSWGFVPEDHIVGKPILVWLSLDKDRSLFD
                     GGIRWNRLFRWVHPD"
     gene            complement(10512..11228)
                     /gene="dapB"
                     /locus_tag="ACZPB4_06280"
     CDS             complement(10512..11228)
                     /gene="dapB"
                     /locus_tag="ACZPB4_06280"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HIR1097862.1"
                     /translation="MKIALIGYGKMGKTIEQIAIQRGHQIVSIIDINNAEDIYSEAFK
                     SADAAIEFTTPATAFNNYMKCFEVGVPVVSGTTGWLDRIGEIKEKCEKEGKTFFYASN
                     FSIGVNIFFAMNKYLAKIMNNFPSYDVKMTEVHHIHKLDAPSGTAITLAEGILENIDR
                     KDRWTLENAENATDLPIHAIREGEVPGIHEITYESDVDTISIKHDAKSRAGFALGAVI
                     AAEFTAGKKGFLGMNDLFKF"
     gene            11305..12585
                     /locus_tag="ACZPB4_06285"
     CDS             11305..12585
                     /locus_tag="ACZPB4_06285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2851 family protein"
                     /protein_id="HIR1097863.1"
                     /translation="MERLLHYVWKYKLYASTSLATTEGLPIAVIDPGIQNTDAGPDFF
                     NAKIKIDGTVWAGSVEIHEKASDWLLHHHDSDKAYDSVILHVTGVNDASICRMNGEPI
                     PQLLLSVPEPARKNIDWLLAREVPVPCLERIQDVDSVHLASWMDTLLSERLERKTEDI
                     YRLLDQYQEDWNEVFYILLTRSFGFGVNSDAFEWLAKSLPLRYIQKQRASESQVEAML
                     FGQAGMLSEEGSCHYYRLLRREYEFLRHKFGLKPLDDSLFKSLRIRPTNFPHVKLAQL
                     SAIWHRYDTLFSMILSASSPKEIKDYFRIQPSDYWKNHYHFRYASPEKEKEIGENALD
                     ILLINTVVPLLFAYGGRNKLPEYCTRATRLLESIPPERNHIVTAFTRSGIHVHNAGDT
                     QSLIQLKREYCEKRKCLYCRIGFRLLKRSVNPPP"
     gene            complement(12569..12937)
                     /locus_tag="ACZPB4_06290"
     CDS             complement(12569..12937)
                     /locus_tag="ACZPB4_06290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008781023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097864.1"
                     /translation="MKQTNKVALLPEVYDFLDVLAQTLLEKDYVSYIEHGENIVDDII
                     DFVKTIPYAPHYHLTPYAQVYFSRYGQNLQYTFFKRKSSKHTTWYIFFSRQEDLYIVH
                     YITNNHKDGKYIHAPIKEED"
     gene            complement(12921..13166)
                     /locus_tag="ACZPB4_06295"
     CDS             complement(12921..13166)
                     /locus_tag="ACZPB4_06295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097865.1"
                     /translation="MSEVSGIELEKDAAGNNSYVRIDLKKYGDMINPILKQLGVIGQT
                     QFDKDWERALDPETFRKEAKIRLRELFNQKHSHEANQ"
     gene            complement(13233..13985)
                     /locus_tag="ACZPB4_06300"
     CDS             complement(13233..13985)
                     /locus_tag="ACZPB4_06300"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008781025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0071554 - cell wall organization or
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HIR1097866.1"
                     /translation="MKRFLIGFAFCFLQLAAFSFCSGDEPVPAHFTEWKAETIVDKSE
                     IDRTGLDAWFKSEEISDDVFDRMWLKSWKEDCPLDRSDLRYLKVLHRNADGLPQCGEM
                     VVNAAIADKVLGIFRQLYEAGYRIERMALIDNYGANDETAMRANNSSSFNFRFMTGST
                     TKISKHGLGLAIDINTLYNPYVKRKDDGTWHIEPATAEPYAFDRESRTDIPYKIDHDD
                     LAYKLFTEAGFEWGGDWTSLKDYQHFEINLSL"
     gene            14833..16746
                     /locus_tag="ACZPB4_06305"
     CDS             14833..16746
                     /locus_tag="ACZPB4_06305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HIR1097867.1"
                     /translation="MEDKYVRNSLRFFIGVLLLAVLYSCANIASPNGGPYDEAPPKFV
                     SSTPLPNQINYKGKKVEIIFDELIQIDKPTENVIITPPQMEQPVIRANGRKAVIELMD
                     TLKENTTYTIDFTNSISDNNEKNVLENYSFAFSTGESIDSMEVSGVLLNAENLEPMPG
                     ITIGVHTNLEDSAFTTIPFVRTSRTNDKGEFTIRNMAPGTYRIYALEDVMRSYKYSQP
                     GQQIAFYDSLIVPAFELTTRQDTIWKDSLTIDTVMTVGYTHFMPDNIELRLFKEKVER
                     QYMLKPERTDEKILTLRFNTSLDTIPVPVPLNFTPADSNWYFLQTAEEGKAVHYWLTD
                     SLIWKQDTLQVEVNYLKSDSMNILRPQTDTVQFTVRRRPVEKKKKKKDDEPEPIEFLG
                     MNVNASGSINLYDTVAVTFSEPVAGLTKDHFYLDQKVDTLWEAVDFDFFPDTTNSLNF
                     FIKRPWKYGEEFRLEVDSATIFSAYGKWNDVYSGEFKIKKEDEYGHLYINIEGSDTTA
                     FVELLNSSDQPIRKVKVKDGGVLFMDLKPDKYYARLVLDVNDNGVWDTGNYADKRQPE
                     LVFYCPKMFNIMQNWQVEETWNIKATPMKRQKPIDITKNKPKELTKKKRDYKNEGTQS
                     SSNRNSGVGGLRF"
     gene            16688..17554
                     /locus_tag="ACZPB4_06310"
     CDS             16688..17554
                     /locus_tag="ACZPB4_06310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3108 domain-containing protein"
                     /protein_id="HIR1097868.1"
                     /translation="MREHSLRPIGTAVWAACASKLYICVFFLCVASLTSLRAQTLPLS
                     HGERVDYDLYFKWGLIMSKAGLATLSVKESEYQGAPSWHYNLLFRSAGVIEKVFRMRD
                     TMDCHYSKEPRLLFSSKRTNEGDYYLVDNLQFEYQGSGRIDIHSHRHTLKETKIDTML
                     MAKGRVFDMLGATMYLRSLDWRTMSYGAEFPFMIAIGRELVNARFRYTGQQIVEHKEA
                     KFRTRHFYIDIYDEAFSQAKEAAEVWIGDDENHIPVKIRAKLKIGAAEVYYKDSYNLR
                     APLTCRIVVQKK"
     gene            complement(17849..18256)
                     /locus_tag="ACZPB4_06315"
     CDS             complement(17849..18256)
                     /locus_tag="ACZPB4_06315"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0047617 - fatty acyl-CoA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HIR1097869.1"
                     /translation="MTIHEFLQGDKFALLAGVELLETGNGYAKARMLIKPEHLNGGGV
                     CQGGAIFTLADLAFAAATNSHARLTLSITSNINFFKAESKGYLYAEAKEAFSHKRLAN
                     CEVRITNEAGELIATFNGTGYRKDTELPFTPLV"
     gene            complement(18282..19757)
                     /gene="cysS"
                     /locus_tag="ACZPB4_06320"
     CDS             complement(18282..19757)
                     /gene="cysS"
                     /locus_tag="ACZPB4_06320"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011965001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HIR1097870.1"
                     /translation="MEHPLNIYNTLTRKKEQFIPLHEPHVGMYVCGPTVYGDAHLGHA
                     RPAITFDLLFRYLTHLGYKVRYVRNITDVGHLEHDADDGEDKIAKKARLEQLEPMEVV
                     QYYLNRYHQAMDALNVLPPSIEPHASGHIIEQIELVKKILDNGYAYESQGSVYFDVEK
                     YNKDHKYGILSGRNIEDMLNTTRALDGQDEKHNAIDFALWKCAQPEHIMRWPSPWSDG
                     FPGWHCECTAMGKKYLGEHFDIHGGGMDLIFPHHECEIAQAVASQGDDMVHYWMHNNM
                     ITINGQKMGKSLGNFITLEQFFTGDHPSLQQAYSAMTIRFFILQAHYRSTVDFSNEAL
                     QAAEKGLSRLMEAYGHLMKLQPSATSTVDTKGLREKCFEAMNDDLNSPIVISHLFDAA
                     RAINSVKDGKATLSEEDLKELQEVFHLFLFDILGMKDEASAGGSNYETFSKAVDLLLS
                     IRQQAKANKDWATSDKIRNELTAMGFEIKDTKDGAEWKLSK"
     gene            complement(19848..22214)
                     /locus_tag="ACZPB4_06325"
     CDS             complement(19848..22214)
                     /locus_tag="ACZPB4_06325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1097871.1"
                     /translation="MLIHYCVIAFKNIWKYKVSASISILGLAFALVCFVPILYWMDHE
                     TTYDSFYKDSESIYRVYSAEKQSGKVNKGASKGIENSLREQVPAIEASTTLMLSTENC
                     RTQATPYIQMNMLYTDSTFLEVFPQSFVCGEMNHPLQIVNNMILSERTAVRLFGDAEK
                     AIGQPIHTLMRASLPPYIVTAVVKDPPTHTNLPFDAIINHNMIQHFSQLPPEAQWSFF
                     VMDLYVKLHPSSDPKAFANQLKELPERIGVNKEIELRTLPIREIRHHLNEDTPFTLNF
                     IGLFVVSGALLLFAALFNFLNSYMDLFRQRVREWRLRTVNGATRKQLIEQMSVELGCS
                     VLASLLVALIFIVQVKPLFARWLEIDLEMGRFLFLFAGVGIGTFLILQCAGLVFFGQF
                     SHTATTSLVPKETVKPLLLRRMAVTLQLMISILFIVASLVVMEQMRFVNQKDLGFDPK
                     GLIQLSGFVDVSGKIESTLMQELSALPQVKSFTDTNFKPQHHVDPMAIFTNVEWEGKP
                     LDTKVDFHLYGTDHRFGETFDLKMLMGRWWTEGNELSVVLNESAVRAMGLQDPVGSII
                     RMPWWSDFSVIKEYEIVGVVNDFHALSFRESIHPMLFIPSGGLVNNLYIRVIPGEEGN
                     IAHHITELLPKIDPTLADTRITPIGTLYDQLNQSEIVGLKIFSFLAFACLLISLFGIY
                     AVATASTKRRRKEIAIRKVVGSKASEIIFLFFKEYMRLIVIAGIIAFPISYLVMNYWL
                     QGYAYRIQIQIWWLVGIFITITSMVLGTIREQVCKAANENPSEVIKSQ"
     gene            22410..23777
                     /locus_tag="ACZPB4_06330"
     CDS             22410..23777
                     /locus_tag="ACZPB4_06330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent transcriptional regulator"
                     /protein_id="HIR1097872.1"
                     /translation="MEEKGKILIIDDNKDVLFALNLLLEPYMQKVKVTTQPARIEYFM
                     RTFQPDVVLLDMNFHRDAVSGQEGFEYLGQILEIDPQAVVIFMTAYSDIEKAVKAIKV
                     GATDFISKPWETEKLLATLSSGIRLSHSRKEVGRLREQMKAMKADDTLPELIGESPAM
                     LKVKDTIYKLVETDANILITGESGTGKDLVARLLRHYSPRRDDAFVTIDLGSIPEQLF
                     ESELFGYEKGAFTDARRSKSGRMEMASGGTLFLDEIGNLSLPMQSKLLTAIEKRHITR
                     LGAVEPISIDVRLICATNANLRQLVGEGSFRQDLLYRINTIEITIPPLRERGEDILML
                     ADHFQRLYSRKYKKTIKGLSREAGSKLMKYPWPGNVRELQHVLERAVILNESTVLRPD
                     DFPLYTASYERKKEPDPDLNLEQAERKIIERALRQSNGNMSYAAELLGITRFSLYRKI
                     EKFGL"
     gene            23774..25042
                     /locus_tag="ACZPB4_06335"
     CDS             23774..25042
                     /locus_tag="ACZPB4_06335"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008781031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1097873.1"
                     /translation="MRSYAFTVISHILGIVLSTGLLFYCVHEEIIFCPTFCGIAILYF
                     SIHLYFIQMRQVKYWRYVVDCLRQQDLIQIVRSPYEDKVMRELADDLSEALRSLRGRL
                     MDEEVRQQYFESLLNKVDTAVLVTDREGAIEWKNRAADALLDTRCRLPNEFLEAIKAG
                     KTVVRYGKPSVPQDWAIDATRIDLRGCERWIVSLKNIHSTLERNEMEAWQKLIRVLTH
                     EIMNSITPVISLSETLSKRCKADPDDVRNRSYIQHGVNVIHRRSKGLLDFVENYRRLT
                     RIASPVKTRILVKDFFSDLRRLCPEPSIRFRLPDEPLEWFADRAQMEQVFLNLLKNAC
                     EACAEKPNPEIIVAAQREGNELVFTVRDNGIGVLPEVIDRVFVPFFTTKPSGSGIGLS
                     ICKQIITLHGGHISVESENGKGSCFFLYFN"
     gene            25294..27132
                     /locus_tag="ACZPB4_06340"
     CDS             25294..27132
                     /locus_tag="ACZPB4_06340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="right-handed parallel beta-helix
                     repeat-containing protein"
                     /protein_id="HIR1097874.1"
                     /translation="MKWYLWGAVVLLYSLFGSACSTERRYDLSAYGLSPVENVDNAPA
                     MARALEQIREKCEENQTIVVTLPKGRYEFYPDSAAERVYFISNHDQMNPKKVGLPFEG
                     MKNMVFDGQGSELIFHGRMLPVSLLDSRNCVLKNFSIDFKHPQISQVKVVENDTLKGG
                     ITFEVAPWVRYEIRDSVFVAKGEGWELTPGSGIAFEGDTRHLVYNTSDIPVGVRGLIE
                     VSPRLIKSPRWKDSRLVPGTVIAMRSWERPAPGVFLYHDVNTTLENIKVHYAEGMGLL
                     AQVSENITLDGFSVCLKGADDPRYFTTQADATHFSACKGAIISKNGLYEGMMDDAINV
                     HGTYLKVVRRVNDSTLVGRYMHPQSYGFEWGRVGDSVQFIHSSTMELIGARNRITAIK
                     AVDQPDYRGAKEFEIRFENTVNPSIHEGSGFGIENLEWTPTVLFSDNVIRNNRARGSL
                     FSTPRQTVVENNVFDHTSGTAILLCGDCNGWFETGACRNVLIRKNKFINSLTNMFQFT
                     NAIISIYPEIPDLASQRKYFHSDIVIDANEFITFDRPLVYAKSVDGLVFTNNIVKQNK
                     EYPAFHWNNHRFYFQRVIHSKIENNYFDEGFIRERDVLEENNGYDI"
     gene            27122..27907
                     /locus_tag="ACZPB4_06345"
     CDS             27122..27907
                     /locus_tag="ACZPB4_06345"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008781033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016791 - phosphatase activity [Evidence
                     IEA];
                     GO_process: GO:0006644 - phospholipid metabolic process
                     [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HIR1097875.1"
                     /translation="MIYRKLIVLASLLIGFVNIAFAGVGDLDTLNVRSQAPVKERMPV
                     VAYKFNPKSLILPASLITVGAVGTAIDGMNDFHLFSRKDSVKQIHIDNYLEWGMLGWV
                     FVCDLMGTEKHNWVDQLCLVALAEGMNGLMVHGLKNWVNEPRPDGAPYSFPSGHTSNA
                     FLGAHMAYKEFKDSSPILAYSGYAIAAFVAGSRLYNNRHWVADVVAGAGFGILSVELS
                     YLIYFPIRNAIARRINRNVKNCPIVAAPVFSSNMAGFYLTYQF"
     gene            complement(27937..29454)
                     /locus_tag="ACZPB4_06350"
     CDS             complement(27937..29454)
                     /locus_tag="ACZPB4_06350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH3 auxin-responsive promoter family protein"
                     /protein_id="HIR1097876.1"
                     /translation="MDILTQTISLLFRHRQTEIGRFGQDIDHIQRKQLHALLSTARKT
                     EWGLKYDYKSIRSYSDFCQRLPLQTYDEIKPYVTRMINGERNILWPSVVRWYAKSSGT
                     TNDKSKFLPVTPEILKGCHYKGGFDCVAIYLRNNPESRFFSKKGLILGGSHSPSPLNS
                     EAHQGDLSAVLLQNLNPLVNLIRVPKKPIILMDEWESKIKAIVENTWNKDVNSLSGVP
                     SWMLVLIKAVLKKTGREYLTDVWPNLEVFFHGGISFEPYREQYKTLIPSNKMHYMETY
                     NASEGFFGLQDDPTDPSLLMMPDYGIFYEFIPMNEVGSAHPTVLPLESIETGKNYAMV
                     ITTSGGLWRYQIGDTVRFTSLFPHKFVISGRTKHFINAFGEELMVDNADKAIAMTCLR
                     TGAKVKEYTAAPLFMLDKAKGRHQWFIEFDKKPESLDEFATLLDQNLQKLNSDYEAKR
                     YKEISLQPLEIVIAHDGAFYEWLKQKGKLGGQHKIPRLSNDRTHIEELLRINQSL"
     gene            29535..30548
                     /locus_tag="ACZPB4_06355"
     CDS             29535..30548
                     /locus_tag="ACZPB4_06355"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003872 - 6-phosphofructokinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006002 - fructose 6-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent 6-phosphofructokinase"
                     /protein_id="HIR1097877.1"
                     /translation="MKIGILSSGGDCPGINATIRGVGKTAIMHYGMEVIGIHSGFIGL
                     LNKDVQVFDERSLSGILNLGGTILGTSREKPFRKLLASGDSEKPEIIKKNYEELGLDC
                     LVCIGGNGTQKTANLLSQIGLNVIGVPKTIDNDIWGTDITFGFNTAVNIATESIDRLH
                     STASSHKRVMVVEVMGHHAGWIALYAGMAGGADVILLPELGYDIDKVNEAILDRARRG
                     KPYSIVVVAEGIETPDKKRPSDYITRAIEAGTGIETRDTVLGYTQRGGNPSPFDRNLA
                     TRLGGHATELIANGEFGRMVCMKGDRVESIPLLEVAGKLKLVTPDHDLIVQGKRMGVT
                     FGK"
     gene            complement(30613..33207)
                     /locus_tag="ACZPB4_06360"
     CDS             complement(30613..33207)
                     /locus_tag="ACZPB4_06360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="T9SS type A sorting domain-containing protein"
                     /protein_id="HIR1097878.1"
                     /translation="MKKQYSKFLRILITGMLCIGYFSISSSLAQISEGGLPPSFQFAG
                     SLRSEKLAEQVPVNFSVEDLKTVDAWRVSQGAPLRVAKSIPTSFDIADSGDWISLPDG
                     SQVWQLHLQAKGAIALILYYSDFYIPKGARLYLYNAAKTQVLGAYTHRTHPENGPFAT
                     QAVAGDEVILEYVPAPSGETPRLRIREVGYGYNHLEAIMPEVQEAPGAGFSEACEVNI
                     NCEEGADWQEQKKGVIQMIQYIRNKEGEGGSYICTASLVNNTARDKKPYVLSAFHCSQ
                     DMLGEQTVTPEELAVWLFYFHQEHVGCDNESPIYPIKTMVGCTRKASTPVENGSDGLL
                     LLLNDEIPDDYNVFFNGWDRSNMLSLSGVGIHHPSGDYMKISTYGNYPTESITWRNSD
                     VGKTGATNAHWNATFDATLNGHGVTEGGSSGSPLFNSKGLIIGTLSGGSSSCELPEGL
                     NLYGKLYYHWNKYSDNDTARMDVWLDPLGTGVTSLQGMTQDGKTIGNEYESPTDLKYK
                     QISTGEIQLTWNAPVLEKIAGWGSQDRYQQFGLGGDPFYFAQKWDTKDLQPVHKKTIR
                     KVNFYPQEGVTYGVYIKQGNREYEESFTQLKSGKINSVTLKTPFVIDAKQDLLVAIHV
                     ISYANNTYPACSDEGPAVDGKGNLYSLDGKKWETFSDDELDANVVLSIVISAEEGEFP
                     SSSVFSTSTFSEKPQPMRTGRLSFRKLAIASDAQEAELITAFPELTGYKVYQDTRELT
                     TLPVSQRNYTVKNLATSTPLLQVTALYGTDESAPATVIPETSVGNELEPTGEEVDIQP
                     RIFSNEVQIQNYQQLKSLEIYRADGKLIRSIPQPGSSLSTGDFATGMYIFRLTTEKGS
                     QTVQGIKK"
     gene            complement(33289..34131)
                     /gene="rnc"
                     /locus_tag="ACZPB4_06365"
     CDS             complement(33289..34131)
                     /gene="rnc"
                     /locus_tag="ACZPB4_06365"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HIR1097879.1"
                     /translation="MFRKLYKQLHKRIRLLHNKGREPYLSLSKILGFYPDNLQIYEQA
                     LLHKSSSVETGDGKWLNNERLEFLGDGILDAAVADIVYKRYPNKREGFLTNTRSKIVQ
                     RETMNKVAVQLGLDQMVVYSTKINSHNNHMYGNALEALIGAIYLDQGYDVCYKFIRDV
                     MIEKYIDVDMLVRKEINFKSNLIEWSQKNKISISFDLIESFTDHDGNPVFQSAIKLLG
                     EQIGIGIGYSKKESQQAASKMAVKRLRTDKELQQRISATKKKKAGELTDEKEFSDLPE
                     EETV"
     gene            complement(34133..35398)
                     /gene="fabF"
                     /locus_tag="ACZPB4_06370"
     CDS             complement(34133..35398)
                     /gene="fabF"
                     /locus_tag="ACZPB4_06370"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016269300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HIR1097880.1"
                     /translation="MELKRVVVTGLGAITPLGNTLPETWEGIINGKSGAGPITQFDAS
                     KFKTQFACEVKGFDPLKVMDRKEARKCDRYSLFAIDAAKQAIEDAAMDLDKEDKNRIG
                     VIFASGIGGIKTFDEEVLSYAKIKDTIGPKFNPFFIPKMISDIAAGHISMLYGFHGPN
                     FATVSACASSTNAISDAFNYIRLGKANVIITGGAEAAVSESGVGGFNSMNALSTRNDS
                     PETASRPFSASRDGFVMGEGGACLVLEEMEHALARGAKIYCEIAGTGMSADAYHLTAS
                     HPDGLGAKLVMRNALEDAGMAPEDIDYINVHGTSTPVGDISEVKAIKDVFGEHAYQLN
                     ISSTKSMTGHLLGAAGAVEAILCIMAINDGIIPPTINHAEGDDDPEIDYKLNFTFNKA
                     QKREVKAALSNTFGFGGHNACAIVKKFVK"
     gene            complement(35420..35656)
                     /locus_tag="ACZPB4_06375"
     CDS             complement(35420..35656)
                     /locus_tag="ACZPB4_06375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005844276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HIR1097881.1"
                     /translation="MSEVAERVKAIIVDKLSVEETEVTNEASFTNDLGADSLDTVELI
                     MEFEKEFGISIPDDQAEKITTVGDAIAYIEANAK"
     gene            35811..36371
                     /gene="purN"
                     /locus_tag="ACZPB4_06380"
     CDS             35811..36371
                     /gene="purN"
                     /locus_tag="ACZPB4_06380"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006974 - DNA damage response [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HIR1097882.1"
                     /translation="MKNIAIFASGSGTNAENITRYFANSENVNVAVVLSNNRNVGVHG
                     RVNKLGVPSFVFSRDEFAAGTPILEKLAEYDVCFIVLAGFMNKISDVILQAFPGKIVN
                     IHPALLPKYGGKGMYGMHVHEAVVKAGERESGITIHYINEHYDEGAIIFQASCPVLPS
                     DTPDEVAAKVHALEYAHYPHVIESLL"
     gene            complement(36385..37494)
                     /gene="pdxB"
                     /locus_tag="ACZPB4_06385"
     CDS             complement(36385..37494)
                     /gene="pdxB"
                     /locus_tag="ACZPB4_06385"
                     /EC_number="1.1.1.290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033711 - 4-phosphoerythronate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-phosphoerythronate dehydrogenase PdxB"
                     /protein_id="HIR1097883.1"
                     /translation="MKIIADNTVPYLKGILEPIADVSYLDSKEFTPTNIKDADALIVR
                     SIDKCTRELLEGSRVRLITTATIGYDHIDIHYCEKAGITWKNAPGCNAASVGQYVLSS
                     LVAVALRKGERLAGKTIGIVGVGHVGSIVERLCEAMGMRVLRNDPPRAEQEGEDGFVS
                     LDTIAKEADIITLHVPLTKEGRFATRHLADHAFFDRLERKPWFINSCRGAVHDTQALL
                     QAKRTGKISELIIDCWENEPDIDRELLSEATIATPHIAGFSADGKANGTRMCLENIGC
                     FFGIRIEKIKEVIPPAPTNPFIDLGQFKEHRVEEAILRSFNPEVIDQALRANPHHFER
                     FRAAYDHPREFHAYQAIKADPEEFTVLQKLGFQVG"
     gene            complement(37808..39007)
                     /locus_tag="ACZPB4_06390"
     CDS             complement(37808..39007)
                     /locus_tag="ACZPB4_06390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008781039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HIR1097884.1"
                     /translation="MNNDKIITPSFCYILAANFLLFFAFYLILPILPFYLKEEFMIGK
                     SMIGFILSCYTLAALCIRPFAGYLLDTFARRPLYLVAYFIFTTIFGGYMVATALTLFI
                     ALRVVHGFAFGMVTVAGNTILIDILPSSRRGEGIGYYGLANNIAMSFGPMIGLFMQGN
                     FTYDVIFSCSLLSGSLGFIMAYMVKTPYKQSVKREPISLDRFFLVKGTWAGISLLLLS
                     IPYGMTTTYVAMYAAEIGISVNSGLYFTFMAVGLAVSRLFSGRQVDKGRITLVISLGM
                     YLAAATFFLLAALKELMHWNPVFSSYLYIGIALSQGVAFGTMFPAFNTLFVNLAPNNQ
                     RGTATSTYLTSWDVGIGIGLMAGGSIAQELGGFNYAYLSGACLTVLSTFFFLFKAGPH
                     FNRHKLR"
     gene            complement(39079..>39505)
                     /locus_tag="ACZPB4_06395"
     CDS             complement(39079..>39505)
                     /locus_tag="ACZPB4_06395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HIR1097885.1"
                     /translation="PYQYRLMRLEPKVIWTPNRHWETSYQTDIRYGGSKIGERTRLAP
                     LWNVIQQVQLSYIFSPIEASLSVDHYHNDVNEDQSVNAVFADFSVSWKSGRWQITATA
                     TNLFDKRTYAYTRYASLESYTSWVRIRPREFLVAIRYRL"
BASE COUNT         9798 a         8665 c        10007 g        11035 t
ORIGIN      
        1 aggtagccgc cgtcttgaga aaggcgaaag ccggaagaga gaggagtcag tcgaaagatt
       61 ggctcctttt tttggtatat acaccagccg ttgtagagat gtggcacgct acgtctttac
      121 aaagagggaa cgtggataga ttagtcgttt atttctttag ctagagattc ccgtagtttc
      181 cgtactgccg tggcgatgtg ggcttctaat gtctttactg atatttctag gatatttgcc
      241 gcatccttat atttcatctt atcttcacgg atcagtttaa aagccatctt gcatttatcc
      301 gggagcgtat tgatcgcctc atttaaatga tcgatgcatt ctttagaaat aagttcttcc
      361 tcgggcgtag tatcggtatg tgcgaataaa tcgatcgtat tctcatcgat ctggactttc
      421 tccatatgtt gtgtccggta taggctgatg gctttgtggc gggctatgcc atagatataa
      481 gaatcgaagt tagagatctc cggtaatgac tttctattat tccaaagact tagaaatgta
      541 tcagagacaa tttcctcagc ttctacagag gaaggcacat aaagggatgt aaaccgcatt
      601 agcctctgaa aataggctaa ataaagcgat ttaaaagcag tttgagaatc ggatagtgcg
      661 atttcacaga cccattgcat tatttctttg gagtgttttt ccaagtaact agaatcttgt
      721 taacttattt cccttctaaa tatatagtcg caaatgtata taaaaaccct tagtggatct
      781 ctctcttaaa agagaaatac ttgatgttaa tttcaaccta atttcatatc tggttgtttt
      841 tgaatctaat ccgcaggttg taacatcatt gtaatatgta tgtaacggat gcgaaataat
      901 tgtttcagaa ctttgcgcaa gaattataac aatcagtatg gaaacatttt atttgttctt
      961 ggtcatattt ttgtttgtat tggccatcgt agatttatcg gtcggtgtta gtaatgacgc
     1021 cgtgaatttc ttgaattcag ctatcggcgc aagagccgca tcctttaaag ttattatcgc
     1081 tatcgctgcc gtgggagtct ttgttggtgc ggcgttatcc aatggtatga tggatattgc
     1141 ccggcatggt atttatcaac cccagcattt ttatttctcg gagatcatgt gtatccttgc
     1201 ggccgttatg cttacggatg tggtgttact ggatattttt aactcgttag gtatgccgac
     1261 ctcgacaacg gtttccatgg tgtttgagtt ggtgggtgga acggtagcga ttgccttggt
     1321 aaagatcgct agttcttcag gcgctttgca attgggggat ctgctgaata cagagaaggc
     1381 ttttaccgtg attctgggta tctttctttc tgtggcgatc gcttttttct ttggtgtgat
     1441 cgtgcagtat ctgtcccgga tcttgttctc atttaattat aagaaaagtt ctaaatattt
     1501 tattggtctg ttcggaggtt tagcggccac ttccatcatt tactttatgc tgataaaggg
     1561 actgaagaca agttctttta tgacgggtga gttcaaggat atggtgtatg ccaatacggg
     1621 gatgatcgtt ttgggatgta tggtattttt tacgatcttg atgcaggtat tgcattggtt
     1681 gaaggtgaat gtattcaagg tggtcatttt gatgggtacg tttgccttgg cgttggcttt
     1741 tgccgggaat gacttggtga actttatcgg agtccccttg gctggctatt cctcttatat
     1801 ggacttgatg gcgcagggag ggaccactac cacggataca tttttgatga cctccttgtt
     1861 gggaccggcc cagacacctt ggtatttctt ggtggggtcc gggatcgtga tggtaatcgc
     1921 cttggctacc tccaaaaagg ctcagaacgt ggtgaagact tccttggatc tgtctcgtca
     1981 atcggatgga gaggagtctt tcggtacatc gcctgtcgca cgggtattgg tacggaattg
     2041 cagtaatata tccgctacga tattaagtat cgtgcccact ccggttaaga actggattga
     2101 tagccgtttc gaccaaagcg agatgatcat ggatgacaag gctagcttcg acttggtacg
     2161 tgcctcggtt aacgtggttt tgtccggctt gctgatcgct ttgggaacct ccttgaaatt
     2221 gcctttatct acgacgtatg tggctttcat ggtcgctatg ggtacttcgt tggcagaccg
     2281 tgcttggggg cgtgagagcg ctgtatatcg catcacaggc gtattgtccg tgataggtgg
     2341 ttggttcatt acggcagggg ctgcttttac gatctgtttc atcgtcgctc ttttgattta
     2401 ttggggaggt attccagctt tggtcgctat gattggtttg gcgatctatt cgttggttcg
     2461 tagccacttc gcttataagg ctaaattgcg gaaagaggca ttgaaggagg aggtgaattc
     2521 tacggtgtct aaacttcgta aggctacgga tacccgtgag gctttggccc tgttccgcga
     2581 gcatagccgt gaggaattac aatccgatct ggattttacg gcggaagtat tcggcaaggc
     2641 ggtaaatgga ttcatgaatg agaacctccg tgagttgcgc aaggtcttga ctgccgtgga
     2701 ggagaagaag attcacttga aacaagtgaa acgtgtcggt acgcttggcg ttacccaatt
     2761 ggatcacgat atcgccgtgg agaaggggct ttattattat caaggaaatg acttcgccag
     2821 cgagatcata ttcagtatcc gtcgcttggc agaaccgatg aaagatcata tcgataataa
     2881 tttcagcccg ttgagtccgg tacagaaaga tgattttggt aaggtatctg aacaaatcat
     2941 ctccttcttg agaaattgcg ctactatgat ccgtaaaaac gattatattg gctttgagga
     3001 gctgatcgct gagtcgatta ccttgatgaa ccaacttacc gccttgaaga aaggggagtt
     3061 gaagcgtatc caagggcagt ccggcagcac gaaggtaagc atggtttatt tgaacatggt
     3121 acaagaggcc cagaacgtgg tttcttttac ggcgaacctt ttgaaggtga gcaggaagtt
     3181 ccagaaggaa taatcagtct ctattatatt gggatgatgg gagacggggc atgccccgtc
     3241 tctactggtt tatagggtta gcatcttctt ttctttgact aaatcactct cgtccatccg
     3301 cagggatggg actgtacaca tcttgataaa atctcctgtc tggcaagtat aatcatagta
     3361 gacctgttgt tccggggtaa aatcttcttt atcgatcagt ccgcttttcc ggctcatgaa
     3421 ttcatcgatc tccgtgcttt ctgattcctt gataagaagg attcggcggg cgatcgggtt
     3481 acgattataa tcttgcccga tgtataatcc tcgtaattgg cgaggattct tgaaaaatgg
     3541 tatttgcagg tatatcgtta ccatcgtgaa ttggggcgct tggttctcgt tcagcatgca
     3601 atggaaattc tgaggatcgg gcatgatccc gaatccccat tgagcctctc cataagcgct
     3661 gatccgccct acacggactt gattatccga gggggagagt aggaagggtt ccatcttgag
     3721 gcagtccgag gaggaagaaa ggctgtaact ggtatagatt cctttgaaag cctctatttt
     3781 agaggcggag agccgtgtct cctccatcaa ttgcttggcg aaaggattat cttttaggct
     3841 atccggttcg gcgaactcca tctggtctag gcgaaggatc atctcctcta tatgggaaag
     3901 caaacgtttt ttcgacacgt tattcactag ggcgagcgcc gagtccagtg cttcttccgg
     3961 cgggtaactc ttgatgccct cgaaataatt cggcaatacg gtcgtatata gggaggacaa
     4021 tatgctggga gccatatcga tccagtcggc tatctctttc atcttaaccc cattgcttcg
     4081 tagatattcg atctttcggt agaattcttg aagattgttc atgtgtttat attcttgatt
     4141 taccttacaa aataagagga catatattgc gtttccgttt catgaatgtt acataaatat
     4201 ttctttataa tttattgatt cctagttggg tattaataat atacattcat gggttcagta
     4261 atatgtctgt aacatggcgg ctgtactttt gccttcgaaa ataaaacgac agaagattat
     4321 ggacactgcg atacagagca ataaaacatc ccggaaacgg atttccgatc tccttttcat
     4381 cctatgggcc ggaggggccg ccttgctttc ttattccttg gtatatatgt tgcgtaagcc
     4441 gtatacggct gccgctttcg aggatctgga ggtattcaat atggactata aggtggcggt
     4501 cacgatcgtg cagatcttgg gatacgtggt gtcgaagttc atgggaatta agttgatatc
     4561 ggagttgcgg cgggaagagc gtttgcggtt catcttgatg tccgtggtga tggcggaact
     4621 ttcgttggta ttcttcgggt tgctctcggc tccttataat atagcggcga tgttcttgaa
     4681 cgggctttcg ctgggatgca tgtgggggat tatttttagc tttatagaag gacgtaggat
     4741 gacggatgtc ctcgctagtt tgttgggcgt aagtatggtg atcagttccg gtacagcgaa
     4801 gtctgtcggc ttgtacgtga tggatatatg gcaggtcagc gagttctgga tgcccgcctt
     4861 gatcggggcg gtggcattgc ctttgctagc cttgttggga tatgcgctga accgacttcc
     4921 acagcctacg gaggaggata tcgccttgaa gtcggagcgg gagaccttga acgggcggca
     4981 gcgttgggag ctttttaagc atttcatgcc tttcttgacg atgcttttcg tggcgaatat
     5041 agcgatcgtg gtattgcggg atatcaagga ggacttcttg gtgaatatca tcgatatgtc
     5101 cggttactcg ccttggttgt tcacgcaaat agatagcgtg gtgaccttga ctatcttggc
     5161 gatctttggt ttgatggtgc tcgtgaaaga taattttaag gcgctttcag tcctgtacgg
     5221 tttgattatt acgggcatga tggtcatggc gttcgtgtcg ttcgggcagg agcggatggg
     5281 attgagcccg gtgacatggc ttttcttgca gagcctttgc ctgtatatgg cttacttaac
     5341 cttccagaca attttcttcg atcgcttcat cgcctgtttc aagatacggg gaaacgtcgg
     5401 tttctttatt gtcttaacag attttctggg gtacacgggt acgatactgg tattggtgct
     5461 aaaggaattc gtgggtacgg gattggactg ggaggtattt tataaccaac ttgccggata
     5521 tgtagggatc ttttgctgcg ccacttttgt cgcttccttc gtatatttgc ggcaacgcta
     5581 tcgcaaggag accgctttat gtggctgcga ggaaatagca actcttgaac ctaccgaaaa
     5641 caatgtcctt acgatcgctt aaacaagaaa attattaaat acgatacata cagaatatga
     5701 agaagatttc aggtgtcatt atggattggg ccggtacggc cgtggattat ggatgcttcg
     5761 ctccactgaa cgcttttctc aaggtattct cggaagagaa agggattgat atcacttacc
     5821 ggcaggcccg tgagccgatg ggtctcttga agatcgatca tatcaaggcg atcttgagca
     5881 tgccggaggt gaacgagaag ttccgtgcct tgtataagag ggactggaac aagggggacg
     5941 tggatgagat gtacgctagt ttcgagaaac atttgttcgc ttccttgaag gatttcacca
     6001 ctccgatacc gggagtcttg gagacgatgg cgatgcttcg cgagcaaggt ataaagatcg
     6061 gctctacgac cgggtacacg gcgaagatga tggagattgt ccgtcccgga gccgaggcca
     6121 gaggatatag ggtcgataat ctggtgacac cgaacgaggt tccggccggt cgccccgccc
     6181 cgtatatgat ctataagaat atgatagatt tggcgattcc ttccgtagat caagtggtga
     6241 aggtaggaga tacgatcgct gatattaagg agggcgtgaa cgccaaggta tggagcgtcg
     6301 gtatcgtgac cggtagcaac gagatgggcg tgagcgagga ggaatataac agccgtccgg
     6361 cggaagaatg ggaatctctg aagaaagagg tgcgtgagcg tatgttggcg gcgggggctc
     6421 atttcgtctt ggatacgatc gccgaactgc ccgcttgcat cgagaagatt aacaacagga
     6481 attaagcttg ataaccaaat agaataaaac aatcatatga gaaactattt attattgaca
     6541 ccgggtccgt tgagtacgtc gcagacggta cgtgaggcca tgcttcagga ttggtgtacg
     6601 tgggataagg attataacga gggtatcgtt accccgatcc gtaaaggctt gctggcgata
     6661 gcgggactgg acggggatgc gtacaccagt gtcctgctgc aaggtagcgg aacgtattgt
     6721 gtggaggcta cgatcggggc caccgtgcgt ccggaggata aattgttgat cctcgctaac
     6781 ggtgcttatg gcaaacgtat ggcgcagatc gccgattatt atcatatcaa ttacgtactg
     6841 gtctctttgc atgagacgga actggtaacc ggcgaggtag cccgacgtgc cttggaggaa
     6901 catcccggta tcacgcatct ctcaatggta catagcgaga ccacgaccgg tttgttgaat
     6961 ccgattgagg aggtagccga ggtgatcaag ggccggggga ttacctttat cgtggatgcg
     7021 atgagcagct ttggcggtgt ccctatcgac gtgaaaggtt taggtatcga cttcttggtc
     7081 agtagcgcga acaaatgtat tcaaggagtt cccggcttcg gctttatcct cgcccaaaaa
     7141 gataaattga tggcgacgaa ggggaatgcc cgctcgcttt ccttagatat ctatgcccag
     7201 tgggaagcga tggagaaagg gggaggcaaa tggcgtttca cgtctccgac gcacgtggtt
     7261 cacgctttct accaagccat gaaggaattg aacgaggaag gcggtatcac ggctcgttat
     7321 aagagatatc aagagaatca ccagatattg gtggaaggta tgcgtggatt gggtttcaag
     7381 accttgctgc ccgatgatgc ccaagggcct attatcactt cgttcttata tccttccgcg
     7441 gatttcgatt tcacctcgtt ctacgcacgg ctgaaggaga aaggcttcgt gatctatccg
     7501 ggtaagatct cggatgcgga tacgttccgt atcggtaata tcggagatat cttcccgaaa
     7561 gatatggaag ccttgataca atcgattaaa gagatccggt aattgatgcc cgtaacgtaa
     7621 cgagtccttc ggggcccata ttgaacagca aatccgctat actcagattg gggaggaatc
     7681 cgaatttctc ccggaatact tgataataag gttccgggcg gaaggcggga tcttcccctt
     7741 cgtgtttcgg gcggatcgtt tcccggaaat cgttggctac ctccggttca taatgctcgg
     7801 tgtagacgac tgcgggttgc atatccaaca ggtcacagac cagacggcgc aattcctcgt
     7861 tgaagtcgag gaggaactcg tatttctttt cgtagaaagg agcgaagtca tcggcataat
     7921 actcgaaaaa cggactcata ttgtaggccg ataccaaagc gttccagtgt aggtgccgcc
     7981 agtttccgtg gtcggagata cggatgtcct tggtctggca tttcaaggta tccggcttga
     8041 cgatggggat ggatagggag agtgggccgt tcgcggcggc gatggaacaa cggttacgat
     8101 aggtttgctt cacgtaattc tcggcggtct cgatacggac ctccgggtat tggagcatct
     8161 tacaatattg ttgtatgggg cctagatagg cggtcgctat atatacaggt cgcatgatta
     8221 atgaacgggt ttaaagattc gttgtttgtc ggggctgtac cagcagagcc aagcgttgcc
     8281 gacgatatgg tcggccggta tgaaaccgag atggcgggaa tctaccgcct cgttggtatt
     8341 atcggacagt acccaatagt agtcttgttg gaaaaagaag aaattagtct cccgcccgtc
     8401 cagatataac tttccgtcac ggaaggaagc tttaccatcc gtctcccgca tgatgatctc
     8461 cttgcaggcg gtgagcgagg cggcgtccag cgggtaagcc cggtctttcc gggggacgat
     8521 caacatgtat tcttgcattt gttccccgat aaaatgacgg tttatggcgt cgggcaattc
     8581 ctccctcaat tgatattcct cgaaagccgt gaggctgagc atacagccga aactttcctg
     8641 cctgaaatcc ctaagtggga tgtccaactt ctctaacgtc tccaagaacg tctccttggc
     8701 gctcagtgtt atgaaatagg aacagaggga gcgaggagag cgggggattt tctgcccgtt
     8761 tatcgtatat ccgtccatgc tgacccggat cgtatcgccc ggcataccga tgcatcggct
     8821 gatgaataag ggagcatccg ctgaatctcg agagagcggg ctggtaaaaa gcacgacctt
     8881 gccccggacg ggcttattct tccccggtat tttattgact aggatataat cccctttatg
     8941 caaagcctct tccatagagt ccgtggagat gcgataggac tctatgcaga aaaggcgtat
     9001 gagcatgacg atccccgcgg ctagcgcgaa agctgccagc catttcatga gaactatcag
     9061 gaatcgttgg attgtcataa tacgaagttt tcacctctta atccggatgc acccaacgga
     9121 acaggcggtt ccaacggata ccaccgtcga acagactgcg atccttgtcc aaggatagcc
     9181 aaaccaagat cggcttgccg acaatgtgat cctcgggtac gaaaccccat gagcggctat
     9241 ccgcgctatt atggcggtta tcgcccatca tccagtaata atcgtattta aacgtatagg
     9301 aagtctcggg cttgccgttg atgtagacct tgccgtcctt cacttccaag gtgttgttct
     9361 cgtaattctt gatacaacgg ctgtacaacg ccagattacg ttcgtccaac gggatggtag
     9421 cccctttctt cgggatccaa agcggcccga agttatcacg ggtccagcca gtattgtatc
     9481 cgaccggata ggtagggccg cccaacgtct ccggctcgat gataaccttc ttcacggtag
     9541 gtaacttctc cgctatcgcc aaggcctttt tcgtgagtgg caggcgatat accgggttgt
     9601 actgtccgtt cgcgttaggc gtaaagccta ggtatgacaa taggttctgg taataaccgc
     9661 cgctggaggc cagcatacgg tcatccttgc ttacgtccat taggcggaat tgctcctctg
     9721 tgatcgggga accgtctgtt tcgatgaagt agttgaactg catatctttc gggttctcgg
     9781 cgggtttacc gtctatgtac acttggttgt ctatgagttg gagcgtatca cccggcatac
     9841 cgatacaacg cttcacgtaa ttctcccgtt tgtcgaccgg gcggtacata acctcgccga
     9901 acgtggcctt atccaataag atacgttccc gtccgtactc ctcgaccaag gagtagtaat
     9961 ctgggttttg cactttcacg gcgatcgtgt cgcctgcggg gaagttgaac actacgatat
    10021 cattacgttt cacgtggccc aaacctttca cccgtttgta gccccattcc ggccaatcca
    10081 aatacgattt gcagtttaag ataggcaacg tattttgtac caacgggaag gagatcggag
    10141 tgttcggaac gcgagggccg taacttaatt tgctgacgaa caggtaatct cctaccagca
    10201 aggatttctc tagggaagaa ctcggtatct gatagttctg gaagacgaac aaattgatga
    10261 aataaacggc taccagcgcg aatacgatat cgtccaccca ttccaatacg ttgcgtaccg
    10321 ccgggttctt agaccgtttc caagctcccc aagggatgta gtgcgtcaag aatatatcga
    10381 ctaggacgat taatcccagc agtaaccata agttttgcat ccagatagcg aacaacgtgt
    10441 ataatacggc cgctatacta aacttgatcc attgtttttt cgtgaacttc ttcatctttt
    10501 agctaatacg tttagaattt gaataagtca ttcatgccta ggaaaccttt ctttccggcg
    10561 gtaaactctg ccgctattac ggcgcctagc gcaaatccgg cacggctctt ggcatcatgc
    10621 ttgatactga tcgtatctac gtccgactca tacgtgatct cgtggatacc cggaacctca
    10681 ccctcacgga tggcgtggat cggcaggtcg gtcgcgttct cggcgttctc taaggtccag
    10741 cggtctttac gatcgatgtt ttccaagata ccttcggcca acgtgatagc cgttccactg
    10801 ggtgcgtcca gcttgtggat atggtggact tccgtcattt taacgtcgta ggaggggaag
    10861 ttgttcatga ttttcgccag atacttgttc atggcgaaga agatatttac gccgatgctg
    10921 aagttggagg cgtagaagaa ggttttgccc tctttctcgc atttctcctt gatctcgccg
    10981 atacggtcca gccatccggt agtacccgat acgaccggca cgcctacctc gaaacatttc
    11041 atatagttat tgaaagcggt agccggggta gtaaactcaa tcgccgcgtc ggcgctcttg
    11101 aacgcttctg aatatatatc ctcagcgtta ttgatatcta tgatggaaac aatttgatgt
    11161 cctctttgga tggcgatctg ctcgatcgtt ttgcccattt tcccgtaacc tataagtgca
    11221 attttcatac tttaattcaa ttaatgtcgc aaatatacag aaaatgaatt acatttgaat
    11281 ccaaaatctt aactctgaaa gaatatggaa cgtttattac actatgtttg gaaatacaaa
    11341 ctctacgcga gtacttcatt ggctaccacc gaggggcttc ccatcgctgt tatcgatccc
    11401 ggaatacaaa acaccgacgc cggtcccgac ttcttcaacg ccaagataaa gattgacggc
    11461 acggtatggg ccggaagcgt ggagatccac gagaaagctt ccgattggtt gctgcatcat
    11521 catgattcgg ataaggcata tgactccgtt atcttgcatg taacaggtgt gaatgacgca
    11581 tccatctgcc ggatgaacgg tgagcctatt cctcaattgc tcctatccgt tccggaacct
    11641 gcccggaaaa atatcgattg gttattggca agagaggtgc ccgtcccctg tcttgagcgg
    11701 attcaagatg tggactccgt gcatctggcc tcatggatgg ataccttgct cagtgagcgg
    11761 ctggaacgaa agacagagga tatataccgt ctgctggatc agtaccaaga ggattggaac
    11821 gaggtattct atatcctatt gacccgtagt ttcggctttg gcgtgaatag cgacgctttc
    11881 gagtggttgg cgaaaagcct ccccctgcga tatatccaaa agcaaagggc tagcgagtcg
    11941 caagtagagg cgatgctttt cggacaagcg ggtatgctct cggaagaggg ctcctgccat
    12001 tactaccgtc tgctgaggcg ggaatatgag tttctccgcc ataagttcgg cctcaagcct
    12061 ttggatgact ccttgttcaa aagccttcgc atccgtccga ccaacttccc gcatgtgaag
    12121 ttggcgcaac tgtccgctat ctggcatcgg tacgatacgt tgttctcgat gatcctgtcc
    12181 gcttcttctc ctaaagagat caaggattat ttccgtatcc aaccctcgga ttattggaag
    12241 aatcattatc atttccgtta tgcctctccg gagaaagaga aggagatcgg ggagaatgct
    12301 cttgatatat tgttgataaa cacggttgtc cctttacttt tcgcttatgg ggggcggaat
    12361 aaattaccgg aatattgtac ccgtgcgact cgtttgttgg aaagtatccc accggaacga
    12421 aaccatatcg taaccgcttt cactcgatcc ggtatccatg tccataacgc tggtgatacg
    12481 caatcactca tccagctgaa acgagaatat tgcgagaagc gaaagtgttt gtattgccgg
    12541 attgggttta ggctgctgaa acggagtgtc aatcctcctc cttgatgggg gcatgtatgt
    12601 atttgccgtc tttgtggttg ttagtaatat aatgtactat atataagtct tcctgccggg
    12661 agaaaaatat ataccaagtg gtatgcttac tacttttcct tttaaaaaag gtatattgta
    12721 aattctgccc gtatctgctg aaatagactt gagcgtaggg ggtgagatga taatgtggcg
    12781 cataggggat cgtttttacg aagtcaatga tatcatctac gatgttttct ccatgttcta
    12841 tgtatgagac gtaatctttc tcaagtaagg tttgggctaa aacatctaaa aaatcgtaaa
    12901 cttcagggag taaggctact ttattggttt gcttcatggc tatgtttttg attgaataac
    12961 tctcttaatc gtattttcgc ttctttccgg aatgtctccg ggtcgagtgc tctttcccaa
    13021 tccttgtcaa attgagtttg tccgataacc cctagctgtt tcaatatagg attgatcata
    13081 tccccatatt tctttaagtc gatacggacg tagctgttgt tccctgccgc gtctttctcc
    13141 aattcgatac ctgatacttc tgacatagtt gctctattaa tttggttata tttctattag
    13201 acgcaaagat aaaacaaata atcgaaatat gttcataatg ataggtttat ctcaaaatgc
    13261 tggtaatctt tcaatgaagt ccaatcacca ccccattcaa acccggcttc ggtaaagagt
    13321 ttgtacgcca aatcatcgtg gtctatttta tacgggatgt cggttctact ctcgcggtcg
    13381 aaagcatacg gttcggcagt ggcaggctca atgtgccaag taccgtcgtc ttttcgcttg
    13441 acgtatggat tgtaaagcgt gttgatgtcg atggcaagcc caaggccatg tttggatatt
    13501 ttagtggtcg aacccgtcat gaagcggaaa ttgaatgagg aggagttgtt cgcacgcatc
    13561 gctgtctcat cattggcgcc ataattatcg atcaacgcca tcctctcgat ccggtagcct
    13621 gcttcataga gctggcgaaa tattcccagt actttatctg cgatagcggc gtttactacc
    13681 atctcgccgc attgcggcaa tccatcggca ttgcgatgca gcactttcag gtaacggaga
    13741 tcggatctgt ccaagggaca atcctctttc cacgatttca gccacatgcg gtcgaaaacg
    13801 tcgtcgctga tttcctctga tttgaaccaa gcatccaaac cagtccggtc tatttcagat
    13861 ttatcgacaa tcgtttccgc tttccattcg gtaaaatgag cgggcacggg ttcatcaccc
    13921 gagcaaaacg aaaaagcagc cagttgtagg aagcaaaacg caaagcctat cagaaaacgt
    13981 ttcattgata catcttttta ttagaatttc tcgaatatat gttatatgcg aaacaaatgt
    14041 agtataaagt ttatgaaaag aggagaactt cagacaggta agtgtccata gaaatcactt
    14101 ttggtgtccg cagaaatcac cttttttgtt tcttttcctt tagttatcaa atgcttatgg
    14161 tcttatgggg tcgctatggt tttcctttat agtatgtgcg ttaggagctt tgcgtttgtt
    14221 ttatccggtt gtgcttttgt aaggaataag ttaggtatgg ctgtcttctt gtcgaaaaga
    14281 ggctgcttat cgtgacaagt gatgtgaacg aaaaggacga attaggagcg tgaagtggtg
    14341 aaaataaggc tagggaaccg gaaatagggc tgtttttatg cgaaagtaat ggaaaaagga
    14401 tacgcaagta ctgccgattg gatgcgcaag tactgccgtt gggcatcgga agtagctgtg
    14461 aactggatcg gaagtaagtg cgaatgggca ttcaagtagg ttcatgaacc ggttggggtg
    14521 gtatcggact tctattttgg ctcttttggg gtgaattacg gtgaatggtt tcgctagaat
    14581 aaaaggtcgt ttttcggcat ctatctatga gctagcgtat tgctaattta ttttctcgta
    14641 tttgagagtg aaccgtactt tagtccgaaa tatgcgactt tccggagggt aagatgacaa
    14701 attgtcaaaa tgtcaatcga tgaatcaaac ggaaccttgt cctttgtaaa gatagattaa
    14761 ttagcgtata tatccttatc gttcacagga tttttcccta tttttgtccc tcaattgaaa
    14821 tatgaagatt gaatggaaga taaatacgta agaaatagtt tacggttctt tataggagta
    14881 cttttgttgg ccgtgctgta ctcgtgcgcg aatatagcct cgccgaacgg ggggccttat
    14941 gatgaggccc cgcctaagtt cgtaagcagt acgccgttgc ctaaccagat aaactataag
    15001 ggaaagaagg tggagattat ttttgatgag ttgatccaga tcgataagcc taccgagaac
    15061 gtgatcatca ctccacccca aatggagcaa cccgttatcc gggcgaacgg ccggaaggcg
    15121 gtcatcgagc tgatggatac gttgaaggag aatacgacct atacgataga ctttaccaat
    15181 tcgatctccg ataataatga gaagaatgta ttggagaatt attccttcgc gttctctacc
    15241 ggcgaatcca tcgacagtat ggaggtgtcc ggagtcttgc tgaacgccga gaatctggag
    15301 cctatgccgg gtattacgat cggtgtgcat acgaatctgg aggattccgc ctttacgacg
    15361 atcccatttg tccgtacttc ccgtacgaac gacaagggag agtttacgat tcgtaatatg
    15421 gccccgggga cctatcggat ctatgccttg gaggatgtga tgcgctccta taagtacagt
    15481 cagcccgggc agcagatcgc tttttacgat tccttgatcg tccccgcgtt cgagttgacg
    15541 acccgtcaag atacgatttg gaaagatagc ttgacgatcg atacggtgat gacagtcggt
    15601 tatacccatt ttatgccgga caatatcgag ttgcgcctgt ttaaggagaa agtagagcgt
    15661 caatatatgt tgaagccgga gcgtacggat gagaaaatac taaccttgcg tttcaatacc
    15721 tccttggata ctattccggt accggttcct ttgaatttca ccccggcgga tagcaattgg
    15781 tatttcttgc agacagcgga ggaaggaaaa gccgtgcatt actggttgac cgattctttg
    15841 atctggaagc aagatacgct acaagtggag gtgaattacc tgaaaagtga ttccatgaat
    15901 atacttcgtc cgcagaccga tacggtacaa tttaccgtgc gtcgccgtcc tgtggagaag
    15961 aagaaaaaga aaaaagacga tgagccggaa cccatcgagt ttctgggaat gaacgtaaac
    16021 gcttccggtt ccatcaacct gtatgatacg gtcgctgtta cgtttagcga accggtagcg
    16081 gggttaacga aagatcattt ttatctggat cagaaagtgg atacgctttg ggaagccgtt
    16141 gacttcgatt tcttcccgga tacgacgaat tccttgaatt tcttcatcaa gcgcccgtgg
    16201 aaatatggcg aggaattccg tttggaagta gattccgcca cgatattcag tgcctatggt
    16261 aaatggaacg atgtgtatag cggggaattc aagattaaga aagaagatga gtacgggcat
    16321 ttatatatca atatcgaggg atcggatact accgctttcg tggaattatt gaatagcagc
    16381 gaccagccga tccgtaaggt gaaggtaaaa gatggcggcg tgcttttcat ggacttgaaa
    16441 ccggataaat attatgcccg tttagtatta gacgtgaatg ataacggtgt ctgggatacc
    16501 ggtaattacg ccgataaacg gcagccggag cttgtcttct attgcccgaa gatgttcaat
    16561 atcatgcaga actggcaagt ggaggagact tggaatatca aggctacacc gatgaaacgg
    16621 cagaaaccga tcgatatcac gaagaataaa ccgaaagagc taacgaaaaa gaaaagagat
    16681 tacaaaaatg agggaacaca gtcttcgtcc aataggaaca gcggtgtggg cggcttgcgc
    16741 ttctaaactg tatatatgcg ttttcttttt gtgtgtagcg agtcttacgt ctttgcgggc
    16801 acaaacgttg ccgttatccc atggggaacg ggtggattac gatctttatt tcaaatgggg
    16861 gctgatcatg tcgaaggccg gattggctac cctttccgtg aaagaatcgg aataccaagg
    16921 agcgccgtca tggcattata acctgttgtt ccgctctgcc ggagtgatcg agaaagtctt
    16981 taggatgcgt gatacgatgg attgccatta ctcaaaggag cctcggctct tgttcagctc
    17041 gaagcgcacg aacgagggag actactatct ggtggataat ctccagtttg agtatcaagg
    17101 aagcggtagg atcgatatcc actcgcatcg ccatacatta aaggagacga agatcgacac
    17161 gatgctaatg gcgaaaggac gtgtattcga tatgctggga gctacgatgt atctccgttc
    17221 gctggattgg cggacgatga gttacggggc ggagttccct ttcatgatcg ctatcggccg
    17281 ggagctcgtg aacgcccgtt ttcgctatac gggacaacag atcgtcgagc ataaggaggc
    17341 gaaattccgt acccgccatt tctatatcga tatctacgat gaggcatttt cccaagccaa
    17401 ggaagcggcg gaggtttgga tcggtgatga cgagaaccat atcccggtaa agatccgggc
    17461 gaaactgaag atcggggcgg ccgaggtcta ttataaagac tcctataacc tgcgtgcccc
    17521 acttacttgc cgtatcgtgg tgcaaaagaa atgaaagctt tttagatagg cttgtgtttc
    17581 tcgcacccag ctcatcacgg agctggggcg agagcttttt atattgatag ggtagttatc
    17641 gtgatcgtgt agcattgatg tagacaaata taaaagatgt tttataataa agggggctca
    17701 taaaggcaga ggttatgaca tgtgaataat ttgtttatga catattgttt atttagattg
    17761 atttataatg tgttgcgtat aagcataaaa aagcgaaagc ctttgggaac aaaccccaaa
    17821 ggctttcgct ttttatagaa tttctttttt aaaccaacgg agtgaagggt aattccgtgt
    17881 ctttgcggta acctgtacca ttaaaagtcg cgattaattc tccggcttca ttggtgatac
    17941 ggacttcgca attcgccagt ctcttatggc tgaacgcttc tttcgcttcc gcatataaat
    18001 atcccttact ctccgcctta aagaaattga tgtttgaggt aatggataat gtcaggcgtg
    18061 cgtggctatt agtcgccgcg gcgaaagcca gatccgccaa cgtgaagatc gccccacctt
    18121 gacatacgcc tccaccattt aaatgttcgg gcttgatgag catacgcgcc ttggcgtaac
    18181 cgttgcccgt ttctaataat tcaacgcccg caagcaaggc gaatttatcg ccttgaagaa
    18241 attcatggat tgtcataacc tcttactatt cgcttggtgg attatttgct tagtttccat
    18301 tccgcaccat ccttggtatc ctttatctcg aatcccatcg cggttaattc gttacggatt
    18361 ttatcggaag tcgcccagtc tttgtttgcc ttcgcttgtt ggcggatgga taataataag
    18421 tctacggcct tgctgaaagt ctcgtaatta ctgccacctg cggaagcctc gtctttcatg
    18481 ccaaggatat cgaacaagaa taaatggaat acctcttgta actctttcaa gtcttcctcg
    18541 gacagagtag ccttaccgtc ttttacggaa ttgatcgcac gggcggcatc gaatagatga
    18601 gaaatcacga tcggtgagtt caaatcgtca ttcatggcct cgaaacattt ctcacgaaga
    18661 cctttcgtgt ctacggtaga ggtagcggac ggctgcaact tcatcaaatg tccgtatgcc
    18721 tccatcaagc gtgacaagcc cttctcggca gcttgcaaag cctcattgct gaaatcaacc
    18781 gtgctgcggt aatgcgcttg caggatgaag aaacggatgg tcatggcgga atacgcttgt
    18841 tgcaaggagg gatgatcacc cgtgaagaat tgctccagtg tgatgaaatt acctaatgat
    18901 ttacccatct tctgcccgtt gatggtgatc atattgttgt gcatccaata atgaaccatg
    18961 tcatcccctt gggaagccac ggcttgcgcg atctcgcatt catggtgcgg gaagatcaag
    19021 tccatgccac ccccgtggat gtcgaaatgc tccccgaggt atttcttgcc catagcggta
    19081 cattcgcagt gccaaccggg gaagccgtcg ctccacggag acggccaacg catgatatgc
    19141 tccggctggg cgcatttcca aagggcgaag tcgatggcgt tatgcttctc gtcctgcccg
    19201 tccaacgcgc gggtcgtatt caacatatcc tcgatattgc gacccgagag gatgccgtat
    19261 ttatgatctt tattatattt ctctacgtcg aaatagacgg agccttgact ctcgtaagcg
    19321 tagccgttat ccagaatctt cttgactaac tcgatttgtt cgataatatg tccggaagcg
    19381 tgcggctcga tgctgggagg aagtacgttc agcgcatcca tcgcttgatg ataacgattg
    19441 aggtaatatt gaaccacttc catcggctcc aactgttcta gccgtgcctt cttggcgatc
    19501 ttatcctccc catcatcggc gtcgtgctcc agatgcccta catccgttat attacgtaca
    19561 taacgcactt tatatcctag gtgggtaagg taacggaata gcaagtcgaa cgtgatcgcc
    19621 ggacgtgcgt gtcccaagtg ggcgtcacca taaaccgtgg ggccacatac gtacatacct
    19681 acatgcggct cgtgcagggg tatgaattgc tccttctttc tcgtaagcgt gttgtaaata
    19741 ttcaatggat gttccatatt ctattatata tttaggaatc gcgaacttac ataaaatcct
    19801 tggtattatc aagctgatcg tgaatagtct gtagttttca taggcattca ttgactcttg
    19861 atgacttccg acggattctc attggctgcc ttacatacct gttcacgtat cgtacctaga
    19921 accatgctgg taatggtgat gaatattccc accaaccacc agatctggat ttggatgcga
    19981 taggcgtagc cttgcaacca gtagttcatg acgagatagc tgatcgggaa agcgatgatt
    20041 ccggcgatga caattaatcg catgtattcc ttgaagaaca agaaaatgat ctcggaggct
    20101 ttcgagccta ctactttccg gatagcgatc tctttacgcc gccgtttcgt ggaggctgta
    20161 gcgacggcgt agatgccgaa caaggagatt agcaaacagg cgaaagcgag gaacgagaat
    20221 attttcagcc cgacgatctc ggattggttc agttgatcgt aaagcgttcc gatcggggtg
    20281 atccgggtat ccgctaatgt cgggtctatc ttgggcagta gctccgtgat atggtgggcg
    20341 atgtttcctt cctcgcccgg tatgacccgg atatacagat tattcaccag tccacccgaa
    20401 ggaatgaata gcatcggatg gatactttcc cggaaagata gcgcatggaa atcgttgacg
    20461 acaccgacga tctcgtattc tttgatcacg ctgaaatctg accaccacgg catacggatg
    20521 atgctgccga ctgggtcttg taagcccatg gcacgaaccg ccgactcgtt gagcacgaca
    20581 ctaagttcgt tgccttctgt ccaccatcgg cccattaaca tctttaggtc gaaggtctca
    20641 ccaaatcggt gatcggttcc atagaggtgg aagtccacct ttgtgtccag cggttttccc
    20701 tcccattcca cattcgtgaa gatcgccatg ggatcgacat gatgttgagg cttaaagttc
    20761 gtgtcggtga aacttttgac ctgcggcagg gcacttaact cttgcatcaa cgtggattct
    20821 atttttccgg atacgtctac gaagccggat agttggataa ggccttttgg atcgaaacct
    20881 aaatcttttt gatttacgaa tcgcatttgc tccatgacaa ccagtgatgc tacgatgaac
    20941 aggatactga tcatcaattg taaggtcacg gccatgcggc gtaacaaaag gggtttgact
    21001 gtctctttgg gaacgagcga ggtggttgcc gtatggctga actgcccgaa gaatactaat
    21061 cctgcacatt ggaggatgag gaatgtacct atacctaccc ctgcgaaaag aaacaggaac
    21121 cggcccatct ccaaatcaat ctccagccat cgggcgaaaa gcggcttgac ttggactatg
    21181 aagatcaagg ctaccaacaa ggatgcaagt acggaacagc ctagttcgac agacatttgt
    21241 tcgatcaatt gctttctcgt tgcgccgttg accgtccgta aacgccattc ccgcacacgt
    21301 tgccgaaaga gatccatata ggaattcaag aaattgaaga gggcggcaaa caataatagg
    21361 gcaccagata cgacaaacaa gccgatgaaa tttaaggtaa agggtgtatc ttcattcaga
    21421 tgatgccgga tctcacggat ggggagtgtt cgcaactcga tctccttgtt caccccgata
    21481 cgttcaggta gctcttttag ttgattggcg aaggcttttg ggtctgagct tggatggagt
    21541 ttcacgtata agtccatcac gaagaagctc cattgtgcct ctggaggtaa ctgggagaaa
    21601 tgctgtatca tgttatggtt gatgatcgcg tcgaacggta gattggtatg ggttggtggg
    21661 tctttcacca cagccgtgac gatgtaggga ggtaaggagg ctctcatcaa ggtgtgtata
    21721 ggttgcccaa tcgccttttc cgcgtcgcca aatagacgga ccgccgtacg ttcgctcaag
    21781 atcatgttgt ttacgatttg tagcggatga ttcatttctc cacaaacgaa agattgcggg
    21841 aatacctcta ggaacgtgct gtctgtataa agcatattca tttggatata aggagtcgct
    21901 tgggttcggc agttttcggt tgaaagcata agcgtggtgg aggcttcgat agctgggact
    21961 tgctctcgta agctattctc gatacctttc gaggctcctt tgttcacttt cccggattgt
    22021 ttctcggcgc tatagacacg gtagatggat tcggaatcct tgtagaaaga atcgtaagtg
    22081 gtctcatgat ccatccaata gagtatgggc acgaaacaga cgagggcgaa agccagccct
    22141 aggatactga tggaggcgct gactttatac ttccagatgt ttttgaaggc aatgacacag
    22201 taatgtatta acatggcaat tccgtttttt gatgatatcg ctgatgactc aatttcgctg
    22261 aatccgattc aaatatcatg ccataaatgt aacgtattag aaaatagaat catagaaaaa
    22321 tctgtatttc ttcatgtagt gcgatagcgt acattttttg tgcgataatg cacgtacaag
    22381 ctgtctttat tccctttatc tttgtccgta tggaagaaaa aggaaagata ttgatcatcg
    22441 acgataataa ggatgtgttg ttcgcattga acttactgtt ggagccgtac atgcaaaagg
    22501 tgaaggtaac gacacaaccg gcacgcattg agtatttcat gcgaacgttc caaccggacg
    22561 tggtcttgct ggatatgaat ttccatcggg atgccgtgag cgggcaggag ggttttgagt
    22621 atttgggaca aatcttggag atcgatccgc aagcggtcgt gatcttcatg acggcctatt
    22681 cggatataga gaaagcggtc aaggccatta aggttggcgc taccgatttc atctccaagc
    22741 cgtgggaaac ggagaagttg ctggctaccc tctcgtcggg cattcgattg agccattccc
    22801 gtaaggaggt cggacgtttg cgggagcaga tgaaagccat gaaggcggac gacacattgc
    22861 cggaattgat cggtgagtcg ccggctatgc tgaaggtaaa agacacgatc tacaaacttg
    22921 tggagaccga cgcgaatata ttaattaccg gcgagagcgg taccggaaaa gatctggttg
    22981 ctcgtttgtt gaggcattac tcgccccggc gtgacgatgc tttcgtgacg atcgatttgg
    23041 gaagcatccc ggaacaatta tttgagagtg agttgttcgg ttacgagaaa ggagccttca
    23101 cggatgcccg acggtctaag tcgggacgga tggagatggc ctccggtggt acgctctttc
    23161 tggacgagat cggtaacctg tccttgccga tgcagtctaa attgttgacg gctatagaaa
    23221 aacgtcatat cacccgtttg ggagcggtgg aaccgatctc gatcgatgtt cgtttgatct
    23281 gcgccaccaa cgccaatctg cgtcagctgg tgggcgaggg gagtttccgg caagacttgc
    23341 tctatcggat caataccata gagataacca taccaccgct gcgtgagcgg ggagaggata
    23401 tcttgatgct ggccgatcat ttccagaggc tgtatagccg gaaatacaag aaaacgatca
    23461 aagggttgag ccgggaggcg gggagtaagc tgatgaaata cccttggccc ggtaatgtcc
    23521 gggagttgca gcatgttttg gagcgagccg tgatcttgaa cgagagtacg gtgctgagac
    23581 cggatgattt ccctctctat acggcctcgt acgagcgaaa gaaggaaccg gaccctgatt
    23641 tgaatctgga acaagccgag cggaaaatca ttgagcgagc cttgcggcaa agcaacggta
    23701 atatgagcta tgccgccgag ctattgggta tcacccgttt ttccttgtat cgtaaaatag
    23761 agaagttcgg cttatgagat cgtatgcgtt cacggtcatc tcgcacatcc taggcatcgt
    23821 cttgtctacg ggactcctgt tctattgcgt gcatgaggag attatctttt gtcctacttt
    23881 ttgcgggatc gcgatcttgt atttctcgat tcatctttat ttcatacaga tgcggcaggt
    23941 gaagtattgg cgttatgtgg tggattgctt gcggcagcaa gacttgatcc agatcgttcg
    24001 ttcaccttat gaggataagg tgatgcggga gttggcggac gatttgtccg aggccctgcg
    24061 atctttgcgt ggccgattga tggacgagga ggtaaggcag cagtattttg agagtctgtt
    24121 gaataaggtg gacactgccg tactcgttac tgacagggaa ggggctattg aatggaagaa
    24181 ccgggccgcc gacgcgttgc tggatacgag gtgtcggtta cccaatgagt tcttggaggc
    24241 tatcaaggcg gggaagacgg tggtgcgtta cggaaaacca tccgttccgc aagattgggc
    24301 gatcgatgcc actcgtatcg acttgcgagg ttgcgagcgt tggatcgtca gcttgaagaa
    24361 catccattct accttggagc ggaatgagat ggaggcttgg cagaaattga tccgtgtctt
    24421 gacgcacgag atcatgaact ccatcacacc cgttatctcg ttgtccgaga ccttgagtaa
    24481 acgttgtaaa gcagatccgg atgatgtccg gaatcgttcg tatatccagc atggggtgaa
    24541 tgtcatccat cgccggagta aagggttgct ggatttcgtt gagaattacc ggagattgac
    24601 ccggatcgcc tctccggtaa agacccgtat cttagtgaaa gatttctttt cggatttaag
    24661 gcgtttgtgc cctgagcctt ctatccgttt ccgcttgccg gacgagcctc tggaatggtt
    24721 cgcggatcgg gcgcagatgg agcaggtctt cttgaactta ctgaagaatg cttgtgaggc
    24781 ttgtgcggaa aagccaaacc ccgagattat cgtggcggct cagcgggagg gaaacgaact
    24841 cgtctttacc gtgcgagaca acggtatcgg tgtcttaccc gaggttatcg accgggtttt
    24901 tgtacctttc tttaccacca agccctccgg ctcgggtatc ggtttaagca tctgtaagca
    24961 aataatcacc ttgcatggcg gccatatctc ggtagaatcc gagaatggaa agggtagctg
    25021 tttctttttg tactttaatt gattatcagc ctattgcagt ttttctaaat ttcttatacg
    25081 gaaaacttta gtttcttcaa ggaaaaactt tcgtttctat atagggaaac aaaagtttct
    25141 tactgaggaa acttttgttt tattaggaga aaactcaggc tgctattata ggagattcgt
    25201 gataggattc atgagacgga aagttattgt ctgtttttag tgcgcttacc ctgtaaaata
    25261 cataccttcg cggatatatt taattgattt tctatgaaat ggtatctatg gggggcagtt
    25321 gtcctgcttt attccctgtt tggaagcgct tgttctacgg aacggaggta tgatttgtcg
    25381 gcttatggtt tatccccggt cgagaatgtg gataatgcgc ccgctatggc gagggcattg
    25441 gagcagatac gggagaaatg cgaggaaaac cagacaattg tggtgacctt gcctaagggc
    25501 cgctatgagt tttatcccga tagcgcggcg gagcgtgtct atttcatctc gaatcatgat
    25561 caaatgaatc cgaagaaagt aggtttgcct ttcgagggga tgaagaatat ggtgttcgac
    25621 gggcaaggct cggagttaat cttccacggc aggatgttgc cggtctcttt gctggattcg
    25681 aggaattgtg tcttgaagaa tttcagtata gacttcaagc atcctcagat ttcacaggta
    25741 aaagtggtgg agaacgatac gctgaaaggc gggatcacct tcgaggtggc tccatgggta
    25801 cgctatgaga tacgggatag cgtgtttgta gcgaagggag aaggctggga gttgactccc
    25861 ggttccggta tcgccttcga gggagataca cgtcatttgg tgtataatac aagcgatatc
    25921 ccggtaggcg tgcggggctt gatcgaggtt tctccaaggc tgataaagtc tccccgttgg
    25981 aaagacagcc gtttggtgcc cggtacggtg atcgccatgc gttcttggga acgtccggct
    26041 cccggtgtct tcctgtatca tgacgtgaat acgactctgg agaatatcaa ggttcattat
    26101 gccgagggaa tgggcctctt ggcgcaagtg agcgagaata tcacgctgga tggtttctcc
    26161 gtttgcttga aaggggcgga cgatccgcgg tatttcacga cacaggcgga cgctacccat
    26221 ttctcggcct gcaagggagc gatcatctcc aagaatggct tgtacgaagg gatgatggac
    26281 gacgctatca atgtgcatgg aacttacctg aaagtggtga gacgagtgaa tgactctacc
    26341 ttggtaggcc ggtatatgca cccgcaatcg tatggtttcg aatggggaag ggtaggggat
    26401 tccgtgcagt tcatccattc gagcaccatg gaattgatag gggcgagaaa ccggattacc
    26461 gctatcaagg cagttgatca accggattac cgaggggcga aggagttcga gatccggttt
    26521 gagaatacgg tgaatccttc gatccatgag gggagcggct tcggcataga gaatctggag
    26581 tggacgccga cggtcctatt ctcggataac gtgatccgga ataaccgtgc ccgtggttcc
    26641 ttgttcagca cgcctcggca aacggtcgta gagaataatg ttttcgatca tacctcgggg
    26701 acggcgatcc tgctgtgcgg tgattgcaac ggctggttcg agaccggcgc ttgccggaac
    26761 gtgttgatcc gtaagaataa gttcatcaac tccttgacga atatgttcca atttacgaac
    26821 gctattatct ctatttatcc cgaaatcccg gatttagcgt cgcaaaggaa atatttccat
    26881 agtgatatcg tgatcgacgc gaacgagttt attacgttcg ataggccatt ggtatacgcc
    26941 aagtccgtgg acgggttggt cttcacgaat aatattgtca aacaaaataa ggaataccca
    27001 gccttccatt ggaataacca tcgtttctat ttccagcggg tgatccattc gaaaatagag
    27061 aacaactatt ttgatgaagg gtttatccgg gagagggatg tcttagagga aaataacgga
    27121 tatgatatat aggaaattaa tcgtcttggc aagccttttg ataggcttcg taaacattgc
    27181 gttcgccggc gttggtgatc tcgatacgtt aaacgtacgt tctcaagccc ctgtcaagga
    27241 gagaatgcct gtcgtcgcct ataagtttaa cccgaaaagc ttgattcttc cggcctcatt
    27301 gataacggtg ggagccgtag gcacggcgat cgacgggatg aatgactttc acctgttttc
    27361 ccggaaagat tccgtgaagc aaatccatat cgacaattac ttggagtggg gaatgctggg
    27421 ttgggtattt gtctgcgacc ttatgggaac agagaagcat aactgggtgg accaactttg
    27481 cttggtcgct ttagcggaag ggatgaacgg attgatggtg catgggctga agaactgggt
    27541 aaacgagcct cgcccggacg gggcgcctta ttcgtttcct tccggacata cctcgaatgc
    27601 tttcttaggg gcgcatatgg cttataagga atttaaggat agctcaccta tactcgctta
    27661 ctcgggttat gcgatagcgg cgttcgtggc gggttcccgc ttatacaata acaggcattg
    27721 ggtggcggat gtagtagccg gcgcaggttt cgggatcttg tcggtagagt tatcgtatct
    27781 gatctatttc ccgattcgta acgctatcgc ccggcggatc aatcgaaatg tgaagaactg
    27841 cccgatcgtg gccgctccgg tattcagttc gaatatggcg ggattctatc tgacttatca
    27901 attttaatgc gtcttatgaa taaagcgcat accggcttat agagactggt taatgcgcaa
    27961 aagctcctct atatgcgtgc ggtcgttgct gaggcgtggg atcttgtgct gcccgcctaa
    28021 tttgcctttc tgcttgagcc attcatagaa agcaccgtcg tgggcgataa cgatttccag
    28081 cggttgaagg gagatctctt tataccgctt cgcctcatag tccgagttca gcttttgtaa
    28141 gttctgatct aataaagtgg cgaattcatc gagagattcc ggtttcttgt caaactcgat
    28201 aaaccattgg tgccgtcctt tcgccttatc cagcataaaa agtggggcgg cggtatattc
    28261 ttttactttc gccccggttc gtaggcaagt catggcgatc gccttatcgg cgttatccac
    28321 cattagctcc tcgccgaagg cgttgataaa gtgcttggta cgtccggaga taacgaattt
    28381 atgagggaat aacgaggtga aacgtaccgt atccccgatc tgatagcgcc ataatcctcc
    28441 cgaggtcgtg attaccatcg cgtagttttt cccggtctct atcgattcca gcggtaacac
    28501 ggtcggatgg gcgctaccca cctcgttcat cgggatgaac tcatagaaaa taccgtaatc
    28561 cggcatcata agcaaactgg ggtctgtcgg atcgtcttgc agcccgaaga agccctcgga
    28621 tgcgttatag gtctccatat aatgcatctt attcgatgga atcaaggttt tatattgctc
    28681 ccggtaaggc tcgaaactga ttcccccatg gaagaagacc tccagattag gccatacgtc
    28741 cgtaagatat tccctacccg tttttttcaa tacggccttg atcaatacca acatccaaga
    28801 aggaacaccg gataggctgt ttacatcctt attccaagtg ttctccacga tcgccttgat
    28861 cttgctttcc cattcatcca ttaggataat gggtttcttg gggacgcgta ttaaattgac
    28921 gagcggattg agattttgaa gtaatacggc ggataagtcg ccttgatgag cctcggagtt
    28981 tagcggggaa gggctatggc tgccgcctaa tatcaagcct ttcttggaga agaaacggct
    29041 ttccgggttg ttccgcagat aaatggccac gcaatcgaag ccgcctttat agtggcaacc
    29101 ctttaatatc tcgggggtga cgggcaggaa tttacttttg tcgttcgtgg tcccgctact
    29161 cttagcgtac caccgcacca ccgaaggcca gagaatattc ctttctccgt ttatcattcg
    29221 ggtgacatac ggctttatct cgtcataagt ctgtaaggga agacgttggc agaagtcaga
    29281 ataagagcga atgcttttat aatcatattt gagtccccat tccgtcttgc gtgccgtcga
    29341 aagcagagca tgcagctgtt tgcgctggat atggtctata tcctgcccaa atcgtccgat
    29401 ctccgtttgt cgatggcgga aaaggagcga aatcgtctgt gttaaaatat ccatgctctt
    29461 tttatttgtt cgagtgcaaa tgtaggcatt ctctttttat ttatatcttt gctaggtact
    29521 aaattaacgt tacgatgaaa atagggattc tctcatcggg tggcgattgc cccggtatca
    29581 acgctacgat ccgtggtgtt ggcaagaccg ctatcatgca ttacggcatg gaagtgatag
    29641 gtattcatag cggttttata ggtcttttga ataaagacgt ccaagttttc gatgaacgga
    29701 gcttatccgg catattaaat ttagggggaa ccattttagg aacgtccaga gagaagcctt
    29761 tccgtaagct cttggcctcg ggagattcgg aaaagccgga gatcattaag aaaaattatg
    29821 aggagctggg gctggactgc ttggtttgta tcggaggaaa cggtacgcag aagacggcca
    29881 atctgttatc tcagatcgga ttgaacgtga taggcgttcc caagacaatc gataatgaca
    29941 tatggggtac ggatattacg ttcggtttta ataccgccgt gaatatcgcc acggaatcta
    30001 tagaccgtct tcattctacg gctagttcac ataagcgggt gatggtcgtg gaggtgatgg
    30061 gccatcatgc cggatggatc gccttgtatg ccgggatggc tggaggtgcc gacgtgatct
    30121 tacttccgga attgggatac gatatcgata aggtgaacga ggcgatcttg gatcgggctc
    30181 gcaggggcaa accttattcc atcgttgtag tagccgaggg tatcgagact ccggataaaa
    30241 agcgtccttc tgattatatt acccgggcta tcgaggcggg aacgggtatc gagacccggg
    30301 ataccgtatt gggatacacc caacggggtg gaaacccctc tccgttcgac cgtaaccttg
    30361 cgactcgctt gggaggccat gccacggaac tgatcgctaa tggtgaattc ggacgtatgg
    30421 tttgtatgaa aggagatagg gtagaatcca ttcccttgtt agaagtagcg ggaaaactaa
    30481 aattagtgac accggatcat gatttgatcg tacaaggaaa acggatgggg gtaacattcg
    30541 ggaaataaaa taaaaaaggt tgtgtgtcag agaacgcaca acctttttta ctttatacta
    30601 gtaggcggcc gtttatttct taataccttg aacggtttgg cttccctttt cggtagtcaa
    30661 gcgaaagata tacattccag tggcaaaatc acccgtgctg agactgcttc ccggttgcgg
    30721 gatgctacgt atcaactttc catcggccct gtagatctca agcgatttca gttgttgata
    30781 attctggatc tgtacttcat tcgagaagat acgtggttga atgtctactt cttcgcctgt
    30841 tggctccagt tcgttaccta cgctcgtttc cggaattacc gtagccggag cgctctcgtc
    30901 ggtaccataa agtgccgtta cttggagcag aggggtactt gttgccagat ttttcaccgt
    30961 ataattccgt tgagaaacag gtaatgtcgt cagttcccga gtatcttgat ataccttata
    31021 accggtcagc tccggaaaag ccgtaatcaa ctctgcttct tgcgcatcgg aggcgatagc
    31081 cagtttccgg aatgataatc ggcccgttct catgggttgc ggtttctccg agaaagtgct
    31141 cgtggagaat acggaacttg aggggaactc accttcttcc gcgcttatta cgatcgataa
    31201 cacaacattg gcatctagct catcatctga gaatgtttcc catttttttc cgtccaaaga
    31261 atataaattc ccttttccat cgactgcggg gccttcatcg gaacatgccg ggtatgtgtt
    31321 attggcatag cttatcacat gaatggctac cagtaaatcc tgcttcgcgt cgattacgaa
    31381 tggtgtttta agtgtgaccg aatttatttt acctgatttc agttgagtga aactctcttc
    31441 atactcccgg tttccctgtt tgatatagac tccataggtg actccttcct gcggatagaa
    31501 attaaccttc cggatcgttt ttttatgcac cggttgtaga tctttcgtat cccatttctg
    31561 agcgaaatag aatggatctc ctccgagacc gaactgttga taacgatctt gtgatcccca
    31621 accagctatt ttttcgagga ctggggcatt ccatgtcagt tgaatctcac ccgtggagat
    31681 ctgtttgtat ttcaaatcag tcggactttc atactcgttt ccgatcgttt tcccatcctg
    31741 cgtcattccc tgcaacgagg tgacgcccgt tccgagtgga tctagccaga catccatccg
    31801 ggctgtatca ttatcactgt atttattcca gtgataatac aatttaccgt ataaattcaa
    31861 tccttcgggc agttcgcaac tggagcttcc accgctcagc gtacctataa tcaaaccttt
    31921 gctattaaat aaaggcgagc cggaagaacc tccctcggtc accccgtgtc cgtttagcgt
    31981 ggcatcgaaa gtcgcgttcc aatgagcgtt cgtggccccg gttttcccaa catcactatt
    32041 acgccatgta atcgattctg tcggataatt tccataggtg gagattttca tataatcgcc
    32101 ggaaggatga tggatgccta cgcccgagag tgaaagcata tttgaacgat cccatccgtt
    32161 aaagaataca ttataatcgt cggggatctc gtcgttaagc aacagcaaca gtccgtcgga
    32221 accgttttcg acaggggtag aggctttccg tgtacatcct accatggttt ttatcggata
    32281 aatgggtgac tcattatcgc agcccacatg ttcttggtgg aaataaaaca accagactgc
    32341 taattcctcg ggagtaaccg tctgttcgcc cagcatatct tgcgaacaat ggaaggcgga
    32401 taatacataa ggctttttgt cacgggccgt attatttacc agagaagccg tacaaatata
    32461 gcttcctcct tctccctctt tattacggat gtattgaatc atttgtatca cccccttctt
    32521 ttgctcctgc caatcggctc cctcctcgca attgatattc acttcgcaag cttctgaaaa
    32581 gccggctccc ggcgcttcct gtacttctgg catgatcgct tcaagatgat tatacccgta
    32641 accgacctcc cggatgcgta gtcgaggtgt ctcgccggat ggtgccggta catattcgag
    32701 gatcacctca tcgcctgcta cggcttgggt tgcgaacggt ccgttttcag gatgcgtacg
    32761 atgcgtatag gcacccaata cttgggtttt cgctgcgtta tacaggtata accgggcacc
    32821 tttggggata taaaaatcgg agtaatacag gatcaaggcg atcgctcctt tcgcttgaag
    32881 gtgaagttgc catacttggc tgccgtcggg tagtgaaatc caatcgccac tatcggcgat
    32941 gtcgaagctg gttgggatcg acttggctac acgcaacgga gcgccttggc tgaccctcca
    33001 cgcatcgacc gtcttgaggt cttccacact gaaattcact ggaacttgtt ctgctagctt
    33061 ttcacttcga agtgaacctg caaattgaaa gctggggggg agtcctcctt cgctgatctg
    33121 cgccaacgaa cttgaaatcg agaaataacc gatacataac atgccggtta ttaatattcg
    33181 gagaaattta ctgtactgtt ttttcataca tacaacttta tatgagctta ttcttatata
    33241 gctaagaact tgggtatatc aaacaatgta cccaagttct gctgtttatc atacagtttc
    33301 ttcctctggg aggtcagaaa actctttttc atcggttagt tcaccagcct tctttttctt
    33361 tgtggcagag atacgttgct ggagttcttt gtctgtccgc aatcttttga ccgccatttt
    33421 agaagccgct tgctgggatt cttttttgga gtaaccgata cctatgccaa tttgctcgcc
    33481 cagcaattta atcgcgcttt ggaatacagg attcccatca tgatccgtaa aagactctat
    33541 tagatcgaac gagatcgata ttttgttctt ttggctccat tcaatcaagt ttgacttgaa
    33601 atttatctct ttccggacga gcatatctac atcgatatac ttttctatca tcacgtcacg
    33661 gataaactta taacaaacgt cataaccttg atccagataa atagcgccga tcaaagcctc
    33721 gagcgcatta ccatacatat gattgttatg agagtttatc ttggttgaat agactaccat
    33781 ttgatcgagg ccgagttgta cggcgacctt attcatcgtt tcccgttgta cgatcttgga
    33841 gcgtgtgttt gtcaaaaagc cttcccgctt atttgggtag cgcttataga caatatcggc
    33901 gaccgccgca tccaaaattc catctcctaa aaattcaaga cgctcattgt taagccattt
    33961 accatcaccc gtctctaccg atgatgattt atgcaacaag gcctgctcgt aaatctggag
    34021 attatccgga taaaaaccta gaatctttga taaagacaaa taaggctccc tacctttatt
    34081 atgcaggagc cttattcttt tatgtagctg tttgtatagc tttctaaaca cgttatttca
    34141 cgaatttttt aacaatggcg caagcgttgt gtccaccgaa accaaacgta ttcgataaag
    34201 cggctttcac ttctctcttt tgagccttat tgaatgtgaa attcagttta taatctattt
    34261 caggatcatc gtcgccttcc gcatggttaa tggtcggcgg gataatacca tcgtttatag
    34321 ccataataca caggatcgcc tctaccgctc cggcagcacc aagcaagtga ccggtcattg
    34381 actttgtgga actgatattc agttgataag catgttctcc gaacacatct ttgatcgcct
    34441 taacctctga gatatcgcct acgggagtcg atgttccatg aacattgatg taatcaatat
    34501 cttccggagc cattccagcg tcttccaatg cgttgcgcat aaccagcttc gctcctaaac
    34561 catccggatg agaagcggtc aagtgatagg catcggcaga cattccggtt cctgcgatct
    34621 cgcaatatat tttagcgcca cgagccaatg cgtgctccat ttcttccaat accaagcaag
    34681 ctccaccttc acccatcacg aatccgtcac ggctagcgct gaacgggcga gatgcggtct
    34741 cgggagaatc gttacgtgtc gataacgcgt tcatggagtt gaatccacct acacccgatt
    34801 cagaaacagc agcttccgct ccaccggtga tgatgacgtt agccttgcct aaacggatat
    34861 aattgaatgc gtcgctgata gcgtttgtag aagatgcaca agctgagacg gtcgcaaagt
    34921 tcgggccgtg gaatccataa agcatggaaa tatgtccagc cgcgatatcc gagatcattt
    34981 tcgggatgaa gaacgggtta aacttcggac cgatcgtatc cttgatcttc gcataactca
    35041 atacttcctc gtcaaatgtc ttgataccac cgatacctga agcgaaaata acgccgatac
    35101 ggttcttatc ttctttatcc aagtccattg ccgcgtcctc gatcgcttgt ttcgccgcat
    35161 cgatcgcgaa taagctataa cgatcacact tgcgggcttc cttacgatcc ataactttca
    35221 acggatcgaa gcctttaact tcgcatgcaa attgtgtctt gaatttggat gcatcaaact
    35281 gagtaatagg tccagcgcca ctttttccgt tgataatacc ttcccatgtt tcggggaggg
    35341 tattaccaag aggagtaata gctccaagac ctgttactac aactcttttt aattccatac
    35401 ctttagttaa aaggattgat tacttcgcgt tagcctcgat gtaagcgata gcgtcaccta
    35461 cagttgtaat cttttctgct tgatcgtcag gaattgagat accgaattct ttttcgaatt
    35521 ccataatcaa ttctacagtg tcaagagagt ctgctcctaa atcgttagta aagcttgctt
    35581 cgtttgtaac ttctgtttct tcaacactta acttgtcaac gatgatagct tttactcttt
    35641 cagcaacttc agacataact ttttcaattt agattaataa atacgaatat actttttaaa
    35701 tttgcagtgc aaagaaaaga attttttatg ttacaaagca aatttaataa gctaaaaatg
    35761 cggaaaactg cacatttttt cttttcttgt gcatttaaac atctgaaaat atgaaaaaca
    35821 tagcgatttt tgcttccggg tctggtacga atgccgagaa catcacccga tattttgcta
    35881 acagtgaaaa cgttaatgtt gcggttgttt tatcaaataa ccgtaatgtt ggcgtgcatg
    35941 ggcgggtaaa caagttgggc gttccctctt tcgtattctc gcgggatgag tttgcggcgg
    36001 gtacgcctat cttggagaaa ctggcggaat atgacgtttg ctttatcgtg ctggccggtt
    36061 tcatgaataa gatctcggac gtgattcttc aggcttttcc cggaaagatc gtgaacatcc
    36121 atcctgcgtt actccctaaa tatggcggca aggggatgta tggcatgcat gtgcatgagg
    36181 cggtcgtgaa ggctggtgag cgggagtcgg gtattactat acattatatt aatgagcatt
    36241 atgatgaggg cgctatcatc ttccaggctt cttgcccggt attaccttcg gatacgccag
    36301 atgaggtagc tgcgaaagtg catgccttgg agtatgcgca ttatcctcat gtgatcgaaa
    36361 gtttactgta aggctttttt gtcattagcc tacttgaaaa cctagttttt ggagtacggt
    36421 gaattcttcc gggtcagctt tgatcgcttg gtaagcatgg aactcacggg gatgatcata
    36481 cgctgcccta aatcgctcga aatgatgagg attcgctctt agtgcttggt cgattacttc
    36541 tgggttgaaa cttctcaaga tggcttcttc cacacggtgc tccttgaatt gtcccaagtc
    36601 gatgaatggg ttggttgggg caggcggaat gacttccttg atcttttcga tacggatacc
    36661 gaaaaagcat cctatattct ctaggcacat tcgtgtcccg ttcgccttcc cgtcggcgga
    36721 gaaaccggct atatgaggag tggcgatcgt ggcttccgac agtaattccc ggtcgatatc
    36781 cggttcgttc tcccagcaat cgatgatcag ttcgctgatc ttgccggttc gtttggcctg
    36841 caataaggct tgcgtatcat gtacggcacc ccggcaactg ttgataaacc atggttttcg
    36901 ttccaatctg tcgaaaaaag catgatcggc tagatggcgg gtggcgaagc gtccctcctt
    36961 ggtcagcggg acatgcaagg tgatgatatc cgcctctttc gcgatcgtgt ccaaggatac
    37021 gaatccatcc tcaccttcct gctcggcacg gggcgggtca ttgcgaagca cacgcatccc
    37081 catggcctcg catagcctct ccacgatact ccctacatgg cctacgccaa cgataccgat
    37141 agtcttccct gctagtctct ctcctttgcg gagggcgacg gctaccaaag aggataatac
    37201 atattgcccc acggaagcgg cgttgcaacc cggggcgttc ttccacgtga tccctgcctt
    37261 ctcgcaataa tggatatcga tatggtcgta cccgatcgtg gctgtcgtga tgaggcgaac
    37321 ccggctacct tccaatagct cgcgtgtaca tttatctatg ctacgtacga tcaaggcatc
    37381 cgcgtctttt atgttcgtgg gcgtaaactc tttggagtca aggtaggata cgtccgctat
    37441 cggctccaag atccctttta ggtaaggaac cgtgttatct gctattattt tcatcttatc
    37501 agcttgatta tcgttacgcg atattaagta aaaaacaggg gatatacaag tgatgatggc
    37561 ttcttgtcga tttctatatg tgcttttgtt ctcagccgaa agattcggga aaacacgtac
    37621 gagtttcatc caaaacacgt acgacttttt gaaaaaacat gtacgtgttt tgacggaaag
    37681 attctcgtgt tttttgtgct tattcttagt ttcttacgtg cgcagctcat gagtaggctt
    37741 attgtatgga attaaagctt ctcggcttaa ctaaaacgga tagattaatg gaagagccgt
    37801 gcagtactta tcttagcttg tgccgattga aatgaggccc tgccttgaac aggaagaaaa
    37861 acgtagacaa taccgtaagg caagcgccag acaagtaggc gtagttgaag ccacccagct
    37921 cttgtgcgat gctgcccccg gccatcaacc cgataccgat acctacatcc caactagtta
    37981 gatatgtaga agtggctgta ccccgctggt tattgggtgc cagattcacg aaaagcgtgt
    38041 tgaaagcagg gaacatggtt ccgaatgcca cgccttgcga gagggctata cctatgtaga
    38101 gataagagga aaataccgga ttccaatgca tcaactcctt gagcgccgca agaagaaaga
    38161 atgtggccgc cgccaaatac atcccgaggg agataacaag cgtgatccgt cctttatcca
    38221 cttgccgtcc ggagaacagg cgggagacgg cgagtcccac ggccataaag gtgaaataaa
    38281 gtccggagtt tacgctgatc ccgatctcag cggcgtacat cgctacataa gtggtagtca
    38341 taccataagg aatggagagc aataataggg agatacccgc ccaagttccc ttcaccaaga
    38401 aaaagcggtc tagggagatc ggttctcgtt tgaccgattg cttataagga gtcttgacca
    38461 tataggccat gataaaacca aggcttccgg atagcaacga gcaggaaaag atcacgtcgt
    38521 atgtgaagtt cccttgcatg aacagaccga tcatcggtcc gaaactcatg gcgatgttat
    38581 tggctaggcc gtaatagcca ataccttccc cacggcggga ggagggcaag atatcgatca
    38641 gtatcgtatt tccggccacc gtcaccatgc cgaaggcgaa accgtgtacg acgcgtaagg
    38701 cgataaagag ggtaagtgcc gtggctacca tgtatccgcc aaatatggtg gtgaaaatga
    38761 aataagccac cagatataag ggacggcggg cgaaagtatc cagcaaatat ccggcgaacg
    38821 gacggataca gagcgccgct agcgtatagc acgacaagat aaacccgatc atagacttcc
    38881 cgatcatgaa ttcttccttc agataaaaag gcaagatcgg caggattaga tagaaagcga
    38941 aaaaaagcag gaaattcgcc gctagtatat agcaaaagct gggtgtgatt attttatcgt
    39001 tattcataaa gccgcttatt tatcagagtg cgaaattagt tgatttttca caattgtttc
    39061 ccctaaacgg cctaataatt ataaacggta gcggatcgct accagaaact cccggggacg
    39121 gatacgtacc catgaggtat agctttccaa cgatgcgtat cgtgtgtatg cgtaggtacg
    39181 tttgtcgaac aggtttgtcg ccgtggcggt gatttgccaa cgcccggatt tccatgagac
    39241 cgagaagtcc gcgaaaacgg cgttgacgga ttggtcttca ttcacgtcat tgtggtaatg
    39301 atctacggaa agacttgcct ctatgggtga gaaaatgtag gagagttgta cttgttggat
    39361 gacgttccat aagggcgcca aacgggtacg ttctcctatt ttacttcctc cgtaccggat
    39421 atcggtttgg taactggttt cccaatggcg gttgggagtc cagatcactt tgggctctag
    39481 gcgcatgagg cgatattgat aagga
//
LOCUS       DBMDTB010000027        38842 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_421_length_38842_cov_11.949149, whole genome shotgun sequence.
ACCESSION   DBMDTB010000027 DBMDTB010000000
VERSION     DBMDTB010000027.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 38842)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 38842)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38842
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_421_length_38842_cov_11.949149"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(248..1912)
                     /gene="asnB"
                     /locus_tag="ACZPB4_06400"
     CDS             complement(248..1912)
                     /gene="asnB"
                     /locus_tag="ACZPB4_06400"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0070981 - L-asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase B"
                     /protein_id="HIR1097886.1"
                     /translation="MCGITAIFNIHDRAQALRKQALLMSKRIRHRGPDWSGIYQGKTA
                     ILAHERLSIVDPASGGQPLVSPDGKLILCVNGEIYNHQELRERLKGDYEFQTGSDCEV
                     ILALYKKKGIDFIEDLNGIFAFALYDEEKGVYLIARDPIGVIPLYIGYDDEGHLMVSS
                     ELKGLEGFATHYEPFLPGHYFYSEDRKLTRWYTRDWMDYANVKDNPTDVQQLHDALEA
                     AVKRQLMSDVPYGVLLSGGLDSSITSAIAKKYAAKRIETNGKADAWWPQLHSFAIGLK
                     DAPDLIAARKVADAIGTVHHEIHYTIQEGLDALRDVIYHIETYDVTTVRASTPMYLLA
                     RVIRSMGIKMVLSGEGADEVFGGYLYFHKAPNAQAFHEETLRKLSKLYLYDCLRTNKS
                     LCAWGVEGRVPFLDKEFLDVAMRLNPVAKMCPGTIIEKKILREAFSDSLPKEIAWRQK
                     EQFSDGVGYGWIDTLKKITSESVTDKEMANAAKRFPINPPQNKEEYYYRSIFEEHFPS
                     ESAARSVPSIPSVACSTAEALAWDSAFKNMNEPSGRAIKGVHESAY"
     gene            complement(1939..3363)
                     /locus_tag="ACZPB4_06405"
     CDS             complement(1939..3363)
                     /locus_tag="ACZPB4_06405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011965971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate synthase subunit beta"
                     /protein_id="HIR1097887.1"
                     /translation="MGNPRAFLTIHRQEAGYRPVHERIDDFSEVEQTLNSGDRRTQAS
                     RCMDCGVPFCHWACPLGNKQPEWQDLLYKGRYKEAYHVLEQTDDFPEFTGRVCPALCE
                     KSCVLKLSCDEPVTIRENEAAIVEAAFREGYVQPIQPVRNGKKVAVIGSGPAGLTVAN
                     QLNRKGYEVTVFEKDELPGGLLRFGIPNFKLGKHIIDRRIRIMEQEGILFRVNTMVGK
                     EILAKDVVKDFDAVCVAIGAEVPRDLSIEGRHLRGVHFALELLSQQNRILEGIPIPPK
                     SQINCKGKKVLVIGGGDTGSDCVGTANRHGAACVTQIEIMPQPPVGQNPATPWPMYPQ
                     VLKTSSSHEEGCIRRWNLASNRFIGEKNNLIGVEVEEVEWVPSPDGGRPQMRQTGKKE
                     IIEADLVFLAMGFLHPEQEGLIKELRLATDNRDNIAVDNAGYTANSNLFACGDAVSGA
                     SLVVKAMASGRNVARSIDRFLQTN"
     assembly_gap    3521..3620
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<3621..8107)
                     /gene="gltB"
                     /locus_tag="ACZPB4_06410"
     CDS             complement(<3621..8107)
                     /gene="gltB"
                     /locus_tag="ACZPB4_06410"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0015930 - glutamate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0006537 - glutamate biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate synthase large subunit"
                     /protein_id="HIR1097888.1"
                     /translation="MKTNKNHFNSRQGLYDPSYEHDACGVGMLVNIHGEKSHDIIESA
                     LKVLENMRHRGAEGADNKTGDGAGILLQIPHEFILLQGIPVPEKGKYGTGLIFLPKDE
                     EQQASILSILIEEIEKEGLTLMHLRKVPVHTEILGKDAQATEPDIKQIFIIGCNDQQE
                     LELKLYLIRKRVEKRVSATDLPAKDDFYIASLSTKNIVYKGMLESMQLRHYFPDLTQP
                     YFTSGLALVHSRFSTNTFPTWSLAQPFRLLAHNGEINTIRGNRGWMEARESVLSSPRI
                     PDINDIRPIIQPGMSDSASLDNVLEFFVASGMSLPHAMAMLVPESFNEKNPISEDLKA
                     FYEYHSILMEPWDGPAALLFSDGRYAGGMLDRNGLRPARYLITKHDMMVVASEVGVMD
                     FEPNEIKEKGRLQPGKILLIDTEKGEIYYDSELKEQLANAQPYRTWLEKNRVELDELK
                     SGRKIPHKVEGYDKLLRTFGYSREDIERIIVPMCTGGAEPVGSMGNDTPLAILSARPQ
                     ILYNYFRQQFAQVTNPPIDPIREELVMSLTEYIGAVGSNILVPTESHCKMVRLNHPIL
                     TNTQLDLLCNIRYKGFKSVKLPTLFDAEKGCAGLKAALDELCKQAEQSVTDGVNYIIL
                     SDRNVDEKKAVIPSLLAVSAVHHHLISVQKRVQTALVVETGEMREVMHAALLLGYGAS
                     AINPYMAFAILDDLVDRQEIQLNYETAEKNYVKAICKGLFKIMSKMGISTIRSYRGAK
                     LFEAIGLSRDLADTYFGGTTSNIGGIRLEEIAADAIAMHNDTFSHPTDSLLEHKGIYS
                     FRKDGEKHAWNPDTISMLQLATRLGSYKKFKEYSHVVDEKESPIFLRDFLTFKQRTPI
                     PLEQVEPEEAIMRRFVTGAMSFGSISREAHETIAIAMNKIHGRSNTGEGGEDSARFIP
                     REDGLSLRSAIKQVASGRFGVTTEYLVNADEIQIKVAQGAKPGEGGQLPGYKVNDIIA
                     KTRHSIPGISLISPPPHHDIYSIEDLAQLIFDLKNVNPQAEISVKLVSESGVGTIAAG
                     VAKAKADRIVISGAEGGTGASPISSIRYAGIPPELGLSETQQTLVMNGLRGQVRLQTD
                     GQLKTGRDIVLMAMLGAEEFGFATSALIVLGCVMMRKCHMNTCPVGVATQDEELRKRF
                     HGRHEYLVNFFTFLAREVREYLAELGYTKLDDIIGRTDLLMRKPSDHIEKHDLLDLSR
                     LIHLPEQAATQTIHQVTRQLHAIDNVKDVDIIRHAKAAIESGQEVSLDYAIANTDRSV
                     GAMLSGEIAKRYGNIGLPENTLHIKFKGAAGQSFGAFLAHGVHFRLEGEANDYLGKGL
                     SGGHICLMPPVRSTFIAEDNTIAGNTLLYGATSGEVYINGRVGERFCVRNSGAIAVVE
                     GVGDHCCEYMTGGRVVVLGNTGRNFAAGMSGGVAYVWNKNGDFDYYCNMEMVELSLIE
                     DSTSRKELHELIRKHYHHTGSHLAGLMLDNWNKYVDEFIQIVPIEYKKVLQEEQMRKL
                     QR"
     gene            complement(8369..9640)
                     /locus_tag="ACZPB4_06415"
     CDS             complement(8369..9640)
                     /locus_tag="ACZPB4_06415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3843 family protein"
                     /protein_id="HIR1097889.1"
                     /translation="MKNIKIFPKDWLQLHPYKQSTPVDSYYTGIANRIYDIMEKTELV
                     NSFEGEETKQICIRMAAYFEDVISGMGLWRAFILTHKELYGKYLPFYTPDDHYYDDEV
                     NLEDVRFLLWHYTQQYHGYRKGTFVSPDNPANESTGMLIYDLFCKEWTTAPENTRMAK
                     LFALDTRYERQEDYDRLLQWFHYESYILPESARELSDFAHDRWKEQPDLNQEQLNNLL
                     VNSHGMMAYTSKTSLLGLTSPQWLAKILPAEHPDHAVFQNTADESVATLPDDMLEENR
                     QQYETFRKAAGDKLLLYFDKTEDAQTFITETSGLIPAENFHLPEDWQGKKLAIYATPE
                     EGAQVITRDVELIKDENNPFYDANRAAKQALSFFIVKHCSVYFLPELVKRGMLADAQT
                     KSLISPERGKAIIQENWKFLARYFIREYPNR"
     gene            9837..12635
                     /locus_tag="ACZPB4_06420"
     CDS             9837..12635
                     /locus_tag="ACZPB4_06420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015343 - siderophore-iron transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0038023 - signaling receptor activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HIR1097890.1"
                     /translation="MGKSLRGKRLKRLGLFWVGVFLSFSLWAQTGVICGTVTDAKIKE
                     PLIGASVVIEGTTVGAITDIDGNFRIENVKPGTYTVAASYVSYQTQTVKDVPVVACQE
                     AVLNIELSDANLQLQNVVVVAQRKLGTEMAVLNTVRKSLPVVNGISAQQISKTQDSDA
                     AEVLRRIPGITIVDDRFIVVRGLAQRYNNVWLNNATTPSSETDSRAFSFDVLPSSLID
                     NMMIYKSPSAELPADFSGGFVRVMTKNIPDGNTFNVSYQMGFNTNATFRNFQLTDGTA
                     KDYLGFGADVRNLPSSFPAHLGEHSTDEAAAFTRQINQRWGINKFTAIPDQKISLTSH
                     RSYDVGGWKIGNITNLNWSTEFDYSETVNNNYIAYDVKNDVSRPRFEYNDIRYKNTSK
                     LGALFNWSFQRDGSKYELRNFFSQRGVSALTQREGMNYYSDKDIRKWESLYTGRTTYS
                     GQISGVHTLRENVNKVDWTVGYAFASYREPDRKIVNSILDENRTEQPNYYVSDPMRYY
                     QELKDHSASLAANYEHKFTVSDRFAPVLNGGVYGEYKSRTFAARRFGYNLLGSGYDRY
                     ADWDYTELFADENISADKIWMRETTTNSDSYTSENMLGAAYVSAKLNYGEVLNANIGV
                     RMEYYQLKMDGYSSDGTTPVHLDNKTTDFFPSVNVAYNLSQKHLVRAAYGRSVNRPEF
                     REVVPYVYFNFERDANIVGNTELKNAYADNIDLRYEFYPAAGEMITIGGFYKHFKDPI
                     EETYNEAGSGLQYTYHNAKNAETFGVELDVKKNLDFIGLRGLSFVCNAAYIYSRVRFE
                     EGAPERDRPLAGQSPYLVNAGFFYQYDDKGISASLLYNRIGKRIESVGVPMQNQDEDI
                     PDIYEMPRNSLDLTFSKKIGKIVEIKAGIQDILNSKVEYKQFVKLTDDKGGKSEREQL
                     IRSYRPGVDINIGVSLRF"
     gene            12680..14323
                     /locus_tag="ACZPB4_06425"
     CDS             12680..14323
                     /locus_tag="ACZPB4_06425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005641201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HIR1097891.1"
                     /translation="MNRFLLKGLASVLTMAVMFGTVSCSDDDDKPDGSVAVSAVAVSP
                     TTATIKVGESTTLSATITPSDATDKTVTWSTSDEKVATVDAGKVTAVAEGSVTITVTT
                     KDGGKTATCTVTVSNDAPSSKEVILEGNITADLTINAADKNFMKGFVYVKSGATLTIE
                     AGSVIKGVSVSPGEKAASLIIEPGAKIIAEGTVDKPIVFTSDKEPGKRLTGDWGGLII
                     CGNARVNRTNQPTIEGGPGTLYGNTTSDEFNAESSGKLKYVRIEFAGYPLEPDKEING
                     LTFGGVGSGTEVEFVQVSFSNDDSYEWFGGTVNAKHLIAYKGWDDDFDTDFGYTGKLQ
                     FLLSVRDKNIADTSDSNGFESDNDGDGSSNTPLTKPVFSNVTLIGPFYGKVSDKTQAE
                     VEAKTADAANGAKGGKFQAAMHLRRNTSLNVYNSVFTGWPYGLRATDKKGTANDGIAI
                     KNVIFAGMWKNFYEDDKVSENFFNLAGSNTTLATTNEIISKDGDYSSVVASAVQGAEF
                     VDEVLNNSFFEKVTYKGAFDGKNDWTAGWTNWDPQNTEY"
     gene            14426..14896
                     /locus_tag="ACZPB4_06430"
     CDS             14426..14896
                     /locus_tag="ACZPB4_06430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin-antitoxin system YwqK family antitoxin"
                     /protein_id="HIR1097892.1"
                     /translation="MNKKLLLLSAFLAGASWTVLAQDLVLSEGQYYTDETQTTPYTGR
                     YTEFYEDGMLKMELYLKDGRPEGTYVIYYPDGKIAEVRSYYHGIFHGEWRTYSDNGQL
                     IGLASYKEGQKDGPWRIWSDKGNLLYEMFYTAGKKSGVWRSWDEEGNLLSEENQ"
     gene            complement(15072..15503)
                     /locus_tag="ACZPB4_06435"
     CDS             complement(15072..15503)
                     /locus_tag="ACZPB4_06435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HIR1097893.1"
                     /translation="MNEVRIDKWMWATRIFKTRTIAAEACKKGRIMIGGVTIKPSRMI
                     KVGDVIQVRKPPITFSFKVIGLIENRVGAKLVPNYLENVTTPDQYEILEMNRISGFVN
                     RAKGLGRPTKKDRRELEQFTEPEFMDDGFDFEFDFGEEDEE"
     gene            complement(15525..16088)
                     /gene="pth"
                     /locus_tag="ACZPB4_06440"
     CDS             complement(15525..16088)
                     /gene="pth"
                     /locus_tag="ACZPB4_06440"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - peptidyl-tRNA hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HIR1097894.1"
                     /translation="MKYLITGLGNIGSEYWGTRHNIGFRVVNHLVESVGGNFTEERYG
                     AIARIRVKNCDLIVLKPNTFMNLSGNAVRYWLQKENIPVENLLIVVDDLALPFGTLRL
                     KPKGSDAGHNGLKNIAQLLNTQEYSRLRFGIGSDFPRGGQIDYVLGKFPPEELQLMPE
                     ILDRATEIIKSFCLAGIQITMNQFNNK"
     gene            complement(16174..16758)
                     /locus_tag="ACZPB4_06445"
     CDS             complement(16174..16758)
                     /locus_tag="ACZPB4_06445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0008097 - 5S rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HIR1097895.1"
                     /translation="MKTFELEGKGREIVARSADQKRALKAMRKNNEIPAVLYGGEKVT
                     HFTVTKEAVRKLVYTPEIFVVELSIDGNKTMAIVKDMQFQPVTDEILHMDFLEVSKDK
                     AVVMEVPVVLEGHAEGVKAGGKLSLQMRKLKVKAIYDQIPEKLTINVDHLGLGKTMQV
                     GALHFEGLELMNAKNAVVCAVQLTRAARGAQAKG"
     gene            complement(16895..17686)
                     /locus_tag="ACZPB4_06450"
     CDS             complement(16895..17686)
                     /locus_tag="ACZPB4_06450"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0070401 - NADP+ binding [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HIR1097896.1"
                     /translation="MEKKWALVTGASSGIGLAYAEELASRGYQLVIVSNEEQAIREKG
                     EFLSEKYGIEVLPLYRDLAIPGAAKELYDTCQEKNIPIEVLVNNAGMFFFCETLQAKA
                     NIVEKMLYLHVTTPTQLCYYFGQEMKKRRHGYILNMSSLSCWLPYPGITLYASTKRYL
                     KSFSRGLRSELLDYGVSVTVLCPGAVATNLYNLSDNLKTLAIRLGIMMRPEKLAKKGI
                     NALFHHRASLLPGLFNKICTPLVMLLPHGLVRWIMRTTKLVKLDR"
     gene            complement(17686..18909)
                     /locus_tag="ACZPB4_06455"
     CDS             complement(17686..18909)
                     /locus_tag="ACZPB4_06455"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH:flavin oxidoreductase"
                     /protein_id="HIR1097897.1"
                     /translation="MDKSILFTPGKIGPLTLRNRTIRAAAFESMCPGNAPSEQLFNYH
                     TSVAAGGIGMTNIAYAAVTQSGLSFERQLWMRPDIIPGLRKLTDAIHKEGAAASIQLG
                     HCGNMSHKRICGCTPISASSGFNLYSPTIVRGMRQSEIASMARAYGEAVRLAREAGMD
                     AVEIHAGHGYLISQFLSPYTNHRKDEYGGSLENRMRFMRMCMEEVMKAAGSDMAVTVK
                     TNMRDGFKGGLEIDECLEVARTLQDQCGAHALVLSGGFVSRAPMYVMRGEMPIRTMAY
                     YMPRGYLPIGIRMVGKYMIPSEPFKEAYFLEDALKFRKALHLPLIYVGGLVSRDKIEE
                     VLNDGFEFVAMARALVNEPGFVNRMKEDEHARCDCGHSNYCIARMYSEDMVCHKNVKG
                     LPECIVREIKRLEYK"
     gene            complement(18946..19239)
                     /locus_tag="ACZPB4_06460"
     CDS             complement(18946..19239)
                     /locus_tag="ACZPB4_06460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007758092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PG0541 family transporter-associated protein"
                     /protein_id="HIR1097898.1"
                     /translation="MKAIFISFNQAYYETIVNIMDRNNLKGFTYWDVVQGRGSKTGEP
                     HYGNHAWPTLNSAILTMVEDEKVDHFLEILHNLDKETEAQGLRAFVWNIEKTI"
     gene            complement(19411..22530)
                     /locus_tag="ACZPB4_06465"
     CDS             complement(19411..22530)
                     /locus_tag="ACZPB4_06465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0042908 - xenobiotic transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HIR1097899.1"
                     /translation="MSLYGTAVRKPVSTALVFVAIVIFGLFSLSRLSVDLLPEIETNT
                     IMVMTAYPGASASDIEMNVSKPLENVLNSVSDLKHITSQSRENISIVTLEFNYGIDID
                     VATNDVRDKLDMVESSLPDDVENPIIFKFGTDDIPILILSVTAEESTNALYKILDDKV
                     SNPLARISGVGAVSISGTPIRELQVYCDPYKLEAYGQTIEGISTIIAQENRNTPGGSV
                     DIGSNTYSLRVQGEFTDAKQMLDLVIGSQNGKNVYLRDVARVEDSIEERAQETFNNGT
                     KGGMIVIQKQSGANSVNIAKKVHQKLPEIQASLPSDVKLDVIMDTSTNILNTIDSLKE
                     TIMITFIIVMLVVFVFLGRWRATFIIILTIPISLIASFAYLLASGNTLNIISLSSLSI
                     AIGMVVDDAIVVLENVTTHIERGSQPKQAAVHATNEVAISVIASTLTMLAVFLPLTMV
                     TGMAGILFKQLGWIVSIIMIVSTVGALTLTPMLCSQLLRQQPEKGKLYRMFFTPIEKG
                     LNALDRGYGRFLNWAVRHRKTVIVGATLIFIGSMMLIPVIKTEFFPTQDNARIGITIE
                     LPIGTRQDITRELALDIDKKFREKYPEILISNFTEGTADTDNTFAQLSNNGTHIIEFN
                     INLTSVGDRERGLTEICELMRQDLAQYSEIKKFEVLAGGQEGSMGGETSVNIEIYGFD
                     FAQTDAVANEIARRMRNVKGCSQVNISREDYIPEYQIDFDREKLAINGLNVTTASMYL
                     RNRVNGSTASKYREDGDEYDIKVRYAPEFRESVEDLENILIYNNEGKGIRIRDLGKVV
                     ERMTPPTIERKDRERVITVSAVAGKGAALSDLVAAARNELKQMDIPSDVSWQLGGTFE
                     DQQDTFTDLGILMVLIIILVFIVMAAQFESLVDPFVIMFSIPFAFTGIVLGLAVTQTP
                     LGVMALIGVIMLMGIVVKNGIVLIDYTILCRERGMGIITSVVTAGKSRLRPVLMTTLT
                     TVLGMIPMAVGTGEGSEMWRSMGMTVAWGLSVSTLITLIIVPTVYAVFAANGVKRRRR
                     KIRKALRNN"
     gene            complement(22537..23562)
                     /locus_tag="ACZPB4_06470"
     CDS             complement(22537..23562)
                     /locus_tag="ACZPB4_06470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011965976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HIR1097900.1"
                     /translation="MKTSQMLKVIPIATLALLMSCSGNKSEEATETQNEKVKVKVETV
                     SVQDVEQLSEFTATVEANIKNNIAPQTPFRIEKIFAEVGDHVKAGQLLAKMDATSLKQ
                     AKIQLDNQEIEFKRIDELYKVGGASKSAWDAQKTSLEVARETYKNLVENTQLLSPISG
                     IVTARNYDSGDMYSGGNPIYTVEEIRPVKLMVNVSESLFTKVKKGHEVDIRLDVYGDE
                     VFKGKVNLVYPTIDPATRTFPVEIKIANSDERVRPGMFARVTMSFGHMDHVVAPDRSI
                     VKQSGAGDRYIYVCKDDKVSYQKVKLGRRMGDKYEIISGVEDGDQVVITGQSRLTNGM
                     EVEIENE"
     gene            complement(23609..25000)
                     /locus_tag="ACZPB4_06475"
     CDS             complement(23609..25000)
                     /locus_tag="ACZPB4_06475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HIR1097901.1"
                     /translation="MKRLLMSRKMMLVTFMVLPFLAARPVLAQDTLKLDLGKALEIAL
                     SENPTVKVADKEIQKKKYARKGSYASLFPQISFAGDYNRTLKKQVMYMDFDMGDMGGG
                     SLPEGTDMSSMDEGFEVGRSNNWSLGFNASMPLVNASLWKSLSISALDVELAVEQARS
                     SKIAMVNQVKKSFYAVLLASDSYRVFKQSYDNAMENYLDIKRKYEQGTVAEYDLIRAD
                     VTVKNTEPNLLQAENSLTLAKWQLKALLGMDLDLNIDCDGQLTDFKSSLFADYLSTDT
                     TLSENTDLKQLDLQAEQLKKTLVMQKFDYLPTLSLTGLYQWSAMNNDFKFKNYRWNPY
                     SMIGITLSVPIFSGGSKFYKVKQTKVSIDQLNLQRDDTKRNLQLAVKQYIDNMNTCIK
                     KFDAAQKGVEQAERGYMISQKRYDTGAGTWLEMNDAELALTQARLNFNQSIYDYMVAK
                     ADLEKVLGNEQMN"
     gene            complement(25043..25645)
                     /locus_tag="ACZPB4_06480"
     CDS             complement(25043..25645)
                     /locus_tag="ACZPB4_06480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HIR1097902.1"
                     /translation="MIKEQIINTAFDLFSQYGIKSVSMDDVAKAAGISKRTLYESFED
                     KETLLIEGIDHNTESLGQYLTGLEKEPFNALEVILLFYEEMMKNPRWFNEKFYEDLKK
                     YPKAQQKIEMNKARMGKRCMDLFTRGVKEGVFQKGINFEIMALLVKEQTKMLRPSNVF
                     CKHSITEVYNTILLTFLKGISTEKGRAILDRFDLKQSYDL"
     gene            25957..26862
                     /locus_tag="ACZPB4_06485"
     CDS             25957..26862
                     /locus_tag="ACZPB4_06485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIR1097903.1"
                     /translation="MKNLPLIEVTELIKGIESSDNFQDDLSIADLNGDLINYEEKRLE
                     HSTPMRLNALLMILVQEGTADISVDYIPYKIEKNTFITLMPTHIIQVSKVSKDLRGRL
                     LIVSRSFLDGYTTPAGKKNSMVHYMQIRKNPCAAMSAEETEHISGQFSILREKMKLRT
                     HFFQKEALQNALVGFFIELANIFMGKKELMTAPTLSRKEELFEQFLQLLFEHCKEQHV
                     VTFYAEKLFITPQYLSLILKELTGKSANKWIDDALIVEAKMLLKAPQATVQQVADILH
                     FSDQSTFGKFFKKHMGISPMEYRKS"
     gene            complement(26857..27393)
                     /locus_tag="ACZPB4_06490"
     CDS             complement(26857..27393)
                     /locus_tag="ACZPB4_06490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009268 - response to pH [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HdeD family acid-resistance protein"
                     /protein_id="HIR1097904.1"
                     /translation="MRSINGAVLRSAFAMVLGFVLVLWPEAAITYLVITIGILFILPG
                     LFAILSYFTRPKNENGEKPMFPIEAAGSVLFGAWLVIMPEFFVNILMYLLGALLVIAG
                     VQQLVSLISARKWSNVPLGFYLMPALILITGVMILAYPFGAAANTFVIFGVASIFYGA
                     CELINWYKFRKRIENTGL"
     gene            27578..28666
                     /locus_tag="ACZPB4_06495"
     CDS             27578..28666
                     /locus_tag="ACZPB4_06495"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008998070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016413 - O-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HIR1097905.1"
                     /translation="MKRIVFLDYVRVFACFLVMVVHASENFYGAEGSTDMVGPQSYLA
                     NEADRLWVAVYDGFSRMAVPLFIIVSAFLLAPMKAGLTSWQFYRQRCIRILPPFFIFM
                     ILYSTLPLLWGQIDAETSLKDISRIFLNFPSQAGHLWFMYPLISLYLFIPVISPWLNK
                     ATAKEERFFIGLFLLSTCMPYLNRCFGEVWGQCFWNEYHILWYFSGYLGYLVLAHYIH
                     VHLTWNRSKRLVIGIASMVVGALLTIYSFYVQAIPGVTLVTPEIEIGWAFCTINCVLL
                     TAGTFLAFTCIGNSKSPRLITEMSKLSYGMYLMHIFWLGLWVTVFKHDLALPTVAAIP
                     CIAVSTFICCYVATKIISLIPGSKWIIG"
     gene            28780..29799
                     /locus_tag="ACZPB4_06500"
     CDS             28780..29799
                     /locus_tag="ACZPB4_06500"
                     /EC_number="2.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0071972 - peptidoglycan L,D-transpeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0018104 - peptidoglycan-protein
                     cross-linking [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HIR1097906.1"
                     /translation="MMTRTVFILLISSLCTLSYCTPRTEPAQTEVLTPVDSISKDSAV
                     IMETLPPHIEIEKELLYDKHTLEDTYPYKDTTREFQWEKMKERLSLLESIQKEPSQWA
                     ILQNYKNRNGEAPLVKVFKRDAYKRVSDTLGVERYQSVPLYLLTDTVIPEIYGRDGSL
                     VRIKAMDEDSKFARIQTVYDGEEEWYAPKKYIKQIGDTVVFDKAIFVDRHNQNIATLE
                     HVGSKWLVRSMNPATTGQHRPPYAQETPLGMYVLQEKKSRMIYLVDGSKETGGFAPYA
                     NRFTNGAYIHGVPVNAPRKSLIEYSPSLGTTPRSHMCVRNATSHAQFVYDWAPVNETI
                     VFVLE"
     gene            29834..30574
                     /locus_tag="ACZPB4_06505"
     CDS             29834..30574
                     /locus_tag="ACZPB4_06505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0071972 - peptidoglycan L,D-transpeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0018104 - peptidoglycan-protein
                     cross-linking [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="murein L,D-transpeptidase catalytic domain
                     family protein"
                     /protein_id="HIR1097907.1"
                     /translation="MRRIFLYLFFIVLSVGSISTGGVLRALSPETGSTSVAVMGRQLY
                     EEMRLDQWVCFDAFMQGLRGSEKIDRKNKDILTLIDFSKPSTAERMVVLDIRQKRILY
                     TSLVSHGKNSGGNYATSFSNENGSHKSSLGFYLTENTYQGRNGYSLILNGLEKGINDL
                     AKQRAIVIHGASYSDPSVAASSGRLGRSFGCPALPVSVSKPIINTIKNGTLLFIYAND
                     KNYLTQSSILSTQQENDIFHEKSYRKVL"
     gene            30634..30708
                     /locus_tag="ACZPB4_06510"
     tRNA            30634..30708
                     /locus_tag="ACZPB4_06510"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:30669..30671,aa:Pro,seq:tgg)
     gene            31214..32548
                     /locus_tag="ACZPB4_06515"
     CDS             31214..32548
                     /locus_tag="ACZPB4_06515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011965977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HIR1097908.1"
                     /translation="MKQILLTTVLSLSFATATVAQEKLWTLDECMRYAVENSPSVKKQ
                     VYTSDTYKAERNAAVASFFPAASAKVGAQYSFGRSIDPATNTYENTSTFNNNYGLDAS
                     IPIFTGGQLINQWLMAKSNRRMGVNDIQKAKDDLAMKTMQAYMDVVYYKGTIRMAAEK
                     LEESNRTLYKTRRQEELGLKGKADVAQFEAQVAADDYTLTHQQNLFNTALLTLRECMN
                     YPSDLELEVDTLLPDINYVPEVENVAEIFAYASGNNPTALQAEYQLTQSKYQYRIYKG
                     KLLPSIYLNAGISTSYFENLKSDNAPEGFKDQFKNNRGEYVSFSLSFPLFDGLSRLTN
                     ARRYRNNMRIARETRTEVFRQLQTAVEQSVLDREGYAKEAIQMDKKVKSDELAYRVTL
                     RKYEEGLMSTLDVQTSANTLLESKANLLQKRLMYLLKSKLVDYYKGKPLINE"
     gene            32596..33846
                     /locus_tag="ACZPB4_06520"
     CDS             32596..33846
                     /locus_tag="ACZPB4_06520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008158279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HIR1097909.1"
                     /translation="MDIQLEKKKGLQKKHIPYVAGGVLFVILLGWIIFGDHASTLKVD
                     ARGISIGNVTREQFNDFFRMDGQVQPITVVQLSPEEGGIVQEKVVEEGAQVKKGDIIV
                     RLSNSNLDLQILNAEAELAEKQNFLRNTQVTMEQDKLTNQMEKLQYDMDMNRARRSFN
                     QQEQLYKENLIAKEDYLKAKEDFELASQKHALITERLRQDSISRTIQMDEMEASLANM
                     RKNILLIRERKENLNVRSQIDGELGLLDVVLGQSINPGQKIGQINDLSDYKIEAMIDE
                     HYIDRVKPGLSAAFERQGSSFDLTVRKVYPEVRDGKFRTDFVFTGERPDNIRSGQTYY
                     INLELGQPTESIIIPKGTFFQSTGGSWIFVLDPDGKKAYRRSIKIGRQNPQYYEVLEG
                     LEAGEKVIVSSYESYKDNEVLVLE"
     gene            33859..36236
                     /locus_tag="ACZPB4_06525"
                     /pseudo
     CDS             33859..36236
                     /locus_tag="ACZPB4_06525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866084.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            36254..38581
                     /locus_tag="ACZPB4_06530"
     CDS             36254..38581
                     /locus_tag="ACZPB4_06530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1097910.1"
                     /translation="MNNLLNFKSFFKFLGRNKAYTLIDVFGLSVSLMFVLLIAVYTVQ
                     EMSTDKFHTKADRIYLVGNENWMATGAAIPYKIKERYPEVEKVCPVVAGNSSDIVVVS
                     GDRKLKANVMFADSTFFDFFDFRLLQGTREQALAAGNYAVVSSSFARKMFGTDDPMGR
                     KLVVGDTISATINGVVEDLLHSSIPEADVIVRWEQVRYLNWSLAPDQLGNAGSTSAFV
                     LVREGSDFPSRAEDMAHWFKEFYWPYQYGTAKEVRILPLSEQYFAKAASYSSLRKGDW
                     RFVIVLMSVGLLILIFAVINYINLTVAQAGFRAKEMATRRLLGSSRGELFMRLMLEST
                     LLTFISLIIGVLLALAVVPFVNDLLQTRVDMNVLGRPVWLLALVSLTVAVGVLSGLLP
                     AIIISSSKPIEVVRGTFRAKTKMVFSKFFIVFQNVITITMIAASITMVCQIVHMINAP
                     VGYKTKNLLAMRSVDERQLSAFVGELKGLSCVDRVGKTQGLPLFGSNNWTATYQGQNI
                     SFQQFVMDKECYDMLGLEILRDNHLTTEGWFLNEQAMREMNLSEDAASFMLDRQERPI
                     AIAGIVRDFYCFGNVTTGMNPVMFRFLKDNEDPWMILIETQGDPFAAKEAIGKVYEKV
                     TGLEFEAYFMDERLQNSFDSQIRLAKIVIVFSIIAILISLLGLLAMSTYFIQQRLQEV
                     SVRKVFGSSNRQILVKLVFTFLNYVLIAFVIAIPIIMYFMKDWLSDYSYRIGLSPLIF
                     IAAGLFCLMISFVSVFFQSYRAATSNPVDSFRHRL"
     gene            complement(38691..>38842)
                     /locus_tag="ACZPB4_06535"
     CDS             complement(38691..>38842)
                     /locus_tag="ACZPB4_06535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HIR1097911.1"
                     /translation="DIFWVDFKSLDFKAGTPIKKLTLTNGEIYAGNTTKDFKDSKPLP
                     FLFGI"
BASE COUNT         9499 a         8938 c         9441 g        10864 t
ORIGIN      
        1 acaataactt taacaacagc agccttttct ttatctgtta attgtttttg ttgttgtgcc
       61 atcactgggg tggtagccat gaatgtagcg gctgccaaac taatgcatgt aaagattttc
      121 ttcatataaa tttgttttaa agtgttttat gactctagct ggcaaagtta ttataaaaat
      181 taaatgcacc agcgtttatt attcataaaa gttggtgcat tttgctacta aagaaaagaa
      241 atattcgtca ataagcggat tcatgtacgc cttttatggc cctgccgctt ggctcgttca
      301 tgtttttgaa agccgagtcc caagctaaag cctctgcggt agaacacgct acgctaggaa
      361 tggaaggtac gcttctcgct gcgctttcgc tggggaaatg ctcttcaaag atggagcggt
      421 aataatactc ttccttgttt tggggcggat tgatcgggaa tcgtttggcg gcattcgcca
      481 tctctttatc agtgaccgac tcggaggtta ttttctttaa tgtatcgatc cagccatagc
      541 ctaccccatc cgagaattgc tctttttgcc gccaagcgat ctccttgggc aagctgtcgg
      601 aaaatgcttc tcgaagtatc ttcttctcga tgatcgtacc cgggcacatc tttgccaccg
      661 gattcagacg catggccaca tcaagaaact ctttatccaa gaacggcact cgtccttcta
      721 cgccccatgc gcaaaggctt ttgttcgtgc gcaagcaatc atataaatac agtttgctta
      781 atttacgcag ggtctcttca tggaaagcct gtgcgttcgg ggccttatgg aaatataaat
      841 atcccccgaa tacctcgtcc gccccctcgc cgcttagtac catcttgata cccatgctcc
      901 ggatcacacg ggccaataaa tacatggggg tggaggctcg gacggtagtg acatcatagg
      961 tctctatatg ataaatgaca tctcgtaaag cgtccaatcc ttcttgtatc gtataatgga
     1021 tctcatgatg aaccgtaccg atcgcatccg ctactttacg ggcggcgatc aagtccgggg
     1081 catctttcaa tccgatggcg aacgagtgga gttgaggcca ccatgcgtcc gctttcccat
     1141 tggtctcgat gcgtttcgcc gcgtatttct tggcgatagc ggaggtgatg gaggaatcca
     1201 aacctccgga tagaaggacg ccataaggga catcgctcat cagttggcgt ttgacggcgg
     1261 cttccagcgc atcgtgaagt tgttgtacgt cggtaggatt atctttcacg ttggcgtaat
     1321 ccatccagtc acgggtgtac catctcgtga gtttacggtc ttcgctatag aaataatgac
     1381 cggggaggaa cggctcgtaa tgagtggcga agccttcaag tccttttaac tcagaagata
     1441 ccatcaagtg tccctcgtca tcgtatccga tgtagagcgg gatcacgccg atcgggtcac
     1501 gggcgatcaa gtaaacccct ttctcctcgt catagagagc gaaggcgaaa ataccattga
     1561 gatcctcgat gaaatcaatc cctttcttct tgtataaggc gaggatcacc tcgcaatcgg
     1621 agccggtttg gaactcgtaa tcgcctttta accgttctcg taattcctga tggttgtaga
     1681 tctctccgtt gacgcagagg atgagtttcc cgtcggggct gactaaaggc tgccctccgg
     1741 aggcagggtc tacgatggaa aggcgttcat gggccaagat agcggttttg ccttggtaga
     1801 taccactcca gtccggcccc cggtgacgga ttcgtttact cattaataac gcttgtttac
     1861 gcagggcttg cgctctgtcg tgtatattga atatcgctgt tataccacac atgataattg
     1921 aaaattgaga gttgaaaatt agttggtttg taagaaacgg tcgatggatc gggcgacatt
     1981 acggccggag gccatcgctt ttacgactag gctcgctccg ctgacagcgt ctccgcaggc
     2041 gaataggttg ctgttggcgg tatatccggc gttgtctacg gcgatgttat cgcggttgtc
     2101 ggtagccaat cgcagttctt tgatcaatcc ttcttgctcc ggatgcagga agcccatggc
     2161 gaggaaaacc agatcggcct cgatgatctc tttcttgccg gtctgtctca tttgcggacg
     2221 gcctccgtct ggggagggaa cccattcgac ttcttctacc tcaaccccta tcaggttgtt
     2281 tttctctccg ataaaacggt tagaggctag gttccaccgg cgtatacaac cttcctcatg
     2341 gctgctgctg gttttcagta cttggggata catgggccaa ggtgtcgccg gattctgtcc
     2401 gacgggtggc tggggcatga tctcgatctg ggtgacacag gccgccccat gacggttcgc
     2461 tgtccctacg caatcgctac ccgtatcgcc tccgccaatc actaagactt tcttgccctt
     2521 acaattgatc tggcttttgg gagggatcgg gatgccttct aagatccggt tctgctggct
     2581 taataactcc aaggcgaaat gtacgcctct taaatgacgt ccctcgatag atagatcccg
     2641 gggaacctcg gcgccgatcg ctacgcaaac agcgtcgaaa tctttcacta catctttcgc
     2701 taatatctct ttgccgacca tcgtgtttac acggaaaaga atcccttctt gctccatgat
     2761 gcggatacgg cgatcgataa tgtgcttgcc tagcttgaaa ttggggatgc cgaaacgtag
     2821 caagccgccc ggtaactcat ctttctcgaa tacggtgact tcatatcctt ttcggttcaa
     2881 ttggttcgct acggtcaatc cggcgggacc gctaccgatc acggctacct ttttcccgtt
     2941 gcgtaccggt tggataggct gtacgtatcc ttcccggaaa gcggcttcca cgatagccgc
     3001 ctcgttctca cggatcgtga caggttcgtc gcagctaagt ttcagtacgc agcttttctc
     3061 gcagagggcg gggcagacac gtcccgtgaa ctccgggaaa tcgtcggtct gctctaatac
     3121 gtgatatgcc tctttgtaac ggcctttgta taacaaatct tgccattcgg gttgcttgtt
     3181 acccagcggg caggcccagt ggcagaaggg tacgccacaa tccatgcagc gggaggcctg
     3241 cgtacggcgg tcgccgctgt tcaaggtctg ttctacctcg ctgaaatcat ctatacgttc
     3301 gtggacggga cgatagcccg cctcttgtct atgtatcgtt agaaatgctc ttgggtttcc
     3361 catagttctc ttgtttttgt gtaaatattt agtagtcttt ctgcatctcc gcaatcttgc
     3421 gttggagttt gcgcatctgt tcctcttgga gtactttctt gtattcgatc gggacgatct
     3481 ggatgaactc atccacgtac ttgttccagt tatcgagcat nnnnnnnnnn nnnnnnnnnn
     3541 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     3601 nnnnnnnnnn nnnnnnnnnn cgttggagtt tgcgcatctg ttcctcttgg agtactttct
     3661 tgtattcgat cgggacgatc tggatgaact catccacgta cttgttccag ttatcgagca
     3721 tcaatccggc cagatggctg ccggtatgat gataatgctt gcggatcaat tcatgaagtt
     3781 cctttcgtga ggtgctatcc tcgatcaagg aaagctctac catttccatg ttacaatagt
     3841 aatcgaaatc accattcttg ttccacacgt aagcgacacc accactcatt ccggcggcga
     3901 agttccggcc tgtattgcct aagacgacaa cccggcctcc ggtcatgtac tcgcaacaat
     3961 ggtcgcctac accttccacg acagcgatcg ccccggagtt tcgcacgcag aaacgctctc
     4021 cgacccggcc gttgatatag acctcaccac tggtagcccc atataataag gtattaccgg
     4081 ctatcgtatt gtcttccgct ataaaggtgg agcgtaccgg aggcattaag cagatgtgtc
     4141 cgccactcaa tccttttccg agatagtcgt tcgcctcgcc ttccaaccgg aaatgtacgc
     4201 cgtgagccag aaaggccccg aagctctggc ctgccgcccc cttgaacttg atatgcaggg
     4261 tgttctccgg taacccgatg ttcccgtacc gcttggcgat ctctccggaa agcatggctc
     4321 ctacggaacg atcggtgttg gctatcgcat aatccaacga tacttcctgt ccggattcga
     4381 tggcggcctt tgcgtgacgg atgatatcca catctttcac gttgtcgatc gcatggagtt
     4441 gacgggtgac ttgatggatg gtctgcgtgg cggcttgttc cggtagatgg atcaagcggc
     4501 tgagatccaa taggtcatgt ttctcgatat gatcggaagg tttacgcatg agtaagtccg
     4561 tacggccaat gatatcgtct agtttcgtat agcctagctc tgccagatat tcccgaactt
     4621 cacgggcgag gaaggtgaag aaattcacca aatattcgtg tcgaccatga aagcgtttac
     4681 gtaattcctc atcttgggta gcgacaccta ccggacacgt gttcatatgg catttacgca
     4741 tcatcacaca acctaaaacg atcaaggcgg aggtggcgaa tccaaactcc tcggcaccca
     4801 gcatcgccat caatacgata tcccgtccgg ttttcaattg tccgtctgtt tgcaagcgga
     4861 cttgtccccg gaggccgttc atcactagtg tctgttgagt ctcggataga cctagctcgg
     4921 gtgggattcc ggcgtaacgg atagagctta tcggggaagc ccccgttcct ccttccgccc
     4981 cggagatcac gatccggtcc gctttagctt tggctacgcc ggcggcgata gttcccacgc
     5041 cactctcgga tacgagtttc acactgatct cggcttgagg gttcacgttc ttcagatcga
     5101 agatcaattg cgccaagtcc tcgatcgagt aaatatcgtg gtgaggtggg ggagagatca
     5161 gagagattcc cgggatcgag tgacgggttt tggctatgat atcgttcact ttatagccgg
     5221 ggagctgccc tccttcgccc ggtttcgctc cttgggcgac cttgatctgg atctcgtcgg
     5281 cgtttaccag atattccgtg gtcacgccaa agcgtccgga ggccacttgc ttgatggcgg
     5341 agcggagcga taacccgtcc tcacggggga tgaaacgagc cgagtcctca ccaccctcgc
     5401 ccgtgttact gcgtccgtgt atcttgttca tggctatagc tatcgtctcg tgcgcttccc
     5461 ggctgataga gccgaagctc atcgctcccg tgacaaagcg gcgcatgatc gcttcttccg
     5521 gctctacctg ctccaagggg atcggggtgc gttgtttgaa ggtcaggaag tcacgcaaga
     5581 atatggggct ttccttctca tcaaccacat gggaatattc cttgaatttc ttgtagctcc
     5641 ccaagcgggt agccagttga agcatggaaa tggtatccgg gttccaagcg tgtttctcgc
     5701 catccttgcg gaaggaataa atgcctttat gttccaataa agaatccgtg gggtgggaga
     5761 atgtgtcatt gtgcatggcg atcgcatctg ccgctatctc ttccaagcgg ataccaccga
     5821 tgttgctggt ggttcccccg aagtaagtat ctgccagatc ccggcttagg ccgatcgcct
     5881 cgaaaagctt cgctccccgg taactgcgga tcgtgctgat ccccatcttg ctcataatct
     5941 tgaataaacc cttgcaaatg gcttttacgt aattcttctc ggcagtctcg taattcaatt
     6001 gtatctcttg cctgtctact agatcatcca agatagcgaa agccatatag gggttgatgg
     6061 cactggcccc gtagcctagt aagagggcgg cgtgcattac ctcacgcatc tcgccggttt
     6121 ccactaccag cgctgtttgc acccttttct gcacggagat cagatggtga tgcacggcgc
     6181 ttaccgctaa cagggagggg atcaccgctt ttttctcatc tacgtttcta tcgcttaaaa
     6241 tgatgtagtt aacgccgtcg gtgacggatt gctccgcttg tttacataat tcgtccaagg
     6301 cagctttcag tcctgcgcat cctttctctg cgtcaaacaa agtggggagc ttaacacttt
     6361 taaaaccctt ataccggatg ttacacagga gatccagttg cgtattggtc aagatcggat
     6421 ggttcagccg aaccatttta cagtggctct cggttggaac taagatattg cttcccaccg
     6481 ccccgatata ctcggtcagg ctcatgacga gttcctcgcg gatcgggtcg atcggcgggt
     6541 tggttacttg ggcgaattgt tggcggaaat aattatagag gatttgcgga cgggcggata
     6601 atatggccag tggcgtatcg ttgcccatgg agccgaccgg ttccgcccct cccgtgcaca
     6661 tcggtacgat gatacgttcg atatcctcac ggctgtatcc gaacgtacgc agtagcttgt
     6721 cgtatccctc taccttatga gggatcttac ggccggattt caactcgtcc aattccaccc
     6781 ggtttttctc cagccaagta cggtagggct gggcgttcgc cagttgttcc ttcagctcgc
     6841 tatcgtaata aatctcgcct ttctcggtat cgatgagtaa gatctttccg ggttgcagac
     6901 ggcctttttc cttgatctcg ttaggctcga aatccatgac gccgacttcg gaggccacga
     6961 ccatcatgtc atgtttcgtg atcaggtaac gggcggggcg gagaccgtta cggtctagca
     7021 tgcctccggc gtagcgtccg tcgctaaaga gcagggcggc aggcccgtcc cacggttcca
     7081 tcaagatgga gtgatattcg tagaaagcct ttaggtcttc ggagatcggg ttcttctcgt
     7141 tgaaactctc cggtaccagc atcgccatgg catgcggcag gctcatcccg gaggccacga
     7201 agaattccaa tacgttatcc agtgaggcac tgtcactcat gcccggctgg atgatcgggc
     7261 gtatatcgtt gatatccggg attctggggg aggagagtac gctctcccgg gcctccatcc
     7321 atccccggtt gcctcgtatc gtgttgattt ccccgttatg tgccagtagg cggaaaggtt
     7381 gcgccagact ccaagtgggg aaggtgttgg tgctgaaacg tgagtgtacc aaggccagtc
     7441 cgctagtgaa ataaggttgc gtcaggtccg gaaagtaatg gcgtagctgc atggattcca
     7501 gcatgccttt gtaaacgatg tttttggtgg aaagagacgc tatatagaaa tcatccttgg
     7561 ccggaaggtc ggtggccgat acccttttct cgacccgctt acgtatgagg tatagcttta
     7621 gttccagctc ttgctgatcg ttgcagccga tgatgaatat ctgcttgata tctggttcgg
     7681 tcgcttgtgc gtcctttccc aagatttccg tatgaacggg aactttgcgt aagtgcatca
     7741 aggttaatcc ctctttctcg atctcctcga tgaggatact gaggatactc gcttgctgtt
     7801 cctcgtcttt cgggaggaag attagtccgg tgccatattt gcctttctct ggaaccggaa
     7861 ttccttgcag gaggatgaac tcatgcggga tctgtaatag gattcccgct ccgtcacccg
     7921 ttttgttatc ggctccctca gcgcctcgat gcctcatgtt ctctagtacc ttaagggctg
     7981 attcgatgat gtcgtgcgat ttctcgccgt ggatatttac taacattcct actccacaag
     8041 cgtcatgttc ataagacggg tcgtataatc cttgtctgct attaaaatga ttcttgtttg
     8101 ttttcatttg ctgaccttat gtttgtgtat aaataattat tgcgtcaatt tgttttacaa
     8161 atataggtat taatgacata atgtgattgc ttgccggggc gaaagagcgg gaaaatgata
     8221 agaatatctt gtctgatgtt tctatttgta ataatttact gggtttattc tttttatttg
     8281 aaaggtattt ggtttgtgga tttactaaat gaaagatgag ctaaaaaaga agcaccgtca
     8341 cgttttgcga cagtgctttc tatctgtttt atctattggg atattctcgg atgaaatagc
     8401 gggctaggaa cttccaattc tcttgtatga tcgccttgcc acgttctggg ctgataaggc
     8461 ttttcgtttg cgcgtcggcc agcatgcctc gctttaccag ctcaggcagg aagtaaacgc
     8521 tgcaatgttt cacgatgaag aaagagagcg cttgcttggc ggcacggtta gcgtcgtaga
     8581 agggattgtt ctcatccttg atcagctcca cgtctcgggt gatgacttgg gcgccttcct
     8641 cgggcgtggc gtagatcgcc agtttcttgc cttgccagtc ttcgggaaga tggaagttct
     8701 cggcggggat aaggccggaa gtctccgtga taaatgtttg tgcatcttcg gtcttgtcga
     8761 aatagagaag cagtttgtca cctgcggctt tgcggaaagt ctcgtattgt tggcggtttt
     8821 cctccagcat atcgtcgggc agggtggcta cagactcgtc ggcggtgttc tgaaataccg
     8881 catggtcggg atgctcggcg ggcaatatct ttgccagcca ttgcggggag gtcagaccta
     8941 gcaaggaggt cttgctggtg taggccatca tgccgtggct gttgacgagc aggttgttaa
     9001 gctgctcttg gttgaggtcg ggctgctcct tccagcggtc gtgggcgaag tcgctcagtt
     9061 cccgggccga ctcaggcagg atataggatt cgtaatggaa ccattgcaat agacgatcgt
     9121 aatcctcttg ccgctcgtag cgggtatcaa gggcgaaaag cttggccatg cgggtattct
     9181 ccggcgccgt ggtccactct ttgcagaaca ggtcgtagat aagcatgccg gtggattcgt
     9241 tggcagggtt gtccggactg acaaaagtgc ctttacgata gccgtgatac tgctgggtat
     9301 aatgccaaag gaggaaacgc acgtcctcaa ggttcacctc atcgtcgtaa taatgatcgt
     9361 ccggagtgta gaaggggagg tatttgccgt atagctcctt atgggtaagg atgaaggcac
     9421 gccaaagccc catgccggag atcacgtctt cgaagtaggc ggccatgcgg atacagatct
     9481 gctttgtttc ctcgccctcg aaggagttta ccaactcggt cttctccatg atatcgtaga
     9541 tacggttcgc tattccggta taataggaat ccacgggagt gctttgttta tagggatgca
     9601 actgcaacca gtctttcggg aaaattttaa tgttcttcat gttattaaat gtctttatgc
     9661 attcaggagt gcaaatgtag taaaaatacg ttagctatgt caaacgataa ggaaaagttg
     9721 cggtcttaaa aatgtaacat ttgttgtctt cattgttatt ggatctaaac atctttgaaa
     9781 taccgccccc gtacttttgc gtcgaaatca aagatgaaat aataagtagt aagataatgg
     9841 gaaagagttt aaggggcaaa agattgaaaa ggttagggct tttctgggtg ggagttttcc
     9901 tgtcattctc tctatgggca caaacagggg ttatttgcgg gacggttacg gacgcaaaga
     9961 taaaagaacc gttgatcggc gcctcggtcg tgatcgaggg gactacggtt ggcgctatca
    10021 cggatataga cggtaatttc cgtatcgaga acgtgaaacc aggtacttat acggtagccg
    10081 cctcttacgt gtcgtaccaa acgcaaacgg taaaggatgt tccggtagtc gcatgccaag
    10141 aggcggtgtt gaatatcgag ctttccgatg ctaacctcca attacagaat gtggtcgtag
    10201 tggcccaacg gaaattggga accgagatgg ccgtattaaa taccgtacgt aagagccttc
    10261 cggtcgtgaa tggtatctcc gcccagcaaa tcagtaaaac acaggatagc gatgccgccg
    10321 aggtactacg ccgtatcccg ggaatcacca tcgtggacga tcgttttatc gtagttcgag
    10381 ggcttgcgca acgttataat aatgtatggc tgaacaacgc cacgacccct tccagcgaga
    10441 cggacagccg tgccttctcg ttcgatgtgc ttccttcttc cttgatcgat aacatgatga
    10501 tctacaagag cccctcggcc gagcttccgg cggatttctc cggcggtttc gtgcgggtga
    10561 tgaccaagaa tatcccggac gggaacacct tcaacgtatc ctaccaaatg ggctttaaca
    10621 cgaacgccac cttccgtaac ttccagctga cggacggcac ggcgaaggac taccttggat
    10681 tcggagcgga cgtgagaaac ctgccttcct ctttccccgc ccatttagga gaacactcca
    10741 cggatgaggc ggcagccttt acccgccaaa tcaaccaacg ttgggggatc aacaagttca
    10801 ccgccatccc cgaccagaag atttccctta cctcgcaccg ctcttatgat gtgggcggct
    10861 ggaagatcgg aaatatcacg aacttgaact ggagtaccga gttcgattac tcggagacgg
    10921 tgaataacaa ctacatcgcc tacgacgtga agaacgacgt atctcgtccc cgctttgagt
    10981 acaacgatat ccgctataaa aatacctcca agctaggggc cctctttaac tggtcattcc
    11041 aacgggatgg cagtaaatat gagcttcgca actttttcag ccagcgtggc gtttccgctc
    11101 tgacacaaag ggaaggaatg aactattatt ccgacaagga tatccgtaaa tgggaatccc
    11161 tctataccgg gcgtaccact tactctgggc agatcagcgg tgtgcatacc ttgcgagaaa
    11221 atgtcaacaa ggtggattgg acggtgggct atgccttcgc ctcctaccgt gagccggatc
    11281 gtaagatcgt gaactccatc cttgacgaga accgtacgga acagccgaac tactatgtct
    11341 ctgacccgat gcgttattac caagaattga aggatcacag cgcctcgcta gccgccaact
    11401 acgaacataa attcaccgta tccgataggt tcgctcctgt tctcaatgga ggtgtctacg
    11461 gtgaatataa gagccgtacc ttcgctgccc gtcgctttgg ctacaacctg ttgggtagcg
    11521 gctacgaccg gtatgcggac tgggattata cggagttgtt cgccgacgaa aatatctcgg
    11581 cggataagat atggatgcgt gagacaacta cgaacagtga ctcttatact tccgagaaca
    11641 tgttgggagc cgcctatgtc tccgctaaat tgaactatgg ggaggtgctg aacgctaata
    11701 tcggtgttcg catggaatac taccaattga agatggacgg atatagctcg gacggtacta
    11761 ctccggtaca cttggataat aagacgacgg atttcttccc ttcagttaat gttgcctaca
    11821 acctctcaca aaaacatttg gtccgcgccg cttacggtcg ctcggtcaac cgtccggagt
    11881 tccgagaggt agtgccttac gtgtacttca acttcgagcg agacgcaaac atcgtgggta
    11941 atacggagtt gaagaacgct tacgctgaca atatcgatct tcgttatgag ttctatcccg
    12001 ccgcgggcga gatgatcacg atcggcggtt tctacaagca cttcaaggat cctatcgagg
    12061 agacgtacaa cgaggctggt tccggcctgc aatataccta tcataacgcg aagaacgccg
    12121 agaccttcgg cgtagagttg gacgttaaaa agaacctcga ctttataggg ctgcgaggct
    12181 tgagctttgt gtgcaacgcc gcatatatct atagccgtgt ccgtttcgag gaaggggcac
    12241 cggagcggga tcgccctttg gcagggcaat ccccctactt ggttaatgcc ggttttttct
    12301 accagtacga tgacaagggg atttccgcct ccctgctcta taaccggatc gggaagcgta
    12361 ttgagtcggt cggtgtcccg atgcagaacc aggacgagga tatccctgat atatatgaga
    12421 tgccccgcaa ctcgttggat cttactttct cgaagaagat tggcaagatt gtcgagatca
    12481 aggcgggaat ccaggatata ttgaactcca aggtcgagta caagcagttc gtgaaactga
    12541 cagacgacaa aggcggcaag agcgagcgtg agcaactgat ccgcagctat cgcccgggag
    12601 tggatatcaa tatcggtgtt tcccttaggt tttgatgttt aattgaatat atatatatta
    12661 caaacaaaat gtttttatta tgaacagatt tctcttaaaa ggtttggcct ctgtgttaac
    12721 gatggccgtt atgtttggga ctgtatcgtg tagtgatgac gatgataaac ctgatggctc
    12781 cgtagccgta tcggctgtgg cagtcagtcc tactaccgct actatcaagg tgggcgaatc
    12841 cactaccttg tccgcgacta ttactccaag tgacgctacg gataaaacgg ttacatggag
    12901 tacttccgat gaaaaggtag cgactgttga tgccggtaag gtaacagccg tggccgaagg
    12961 ttccgttacg attactgtaa ctacgaagga tggcggtaaa acggctactt gtaccgtgac
    13021 tgtctctaat gatgctccgt cttccaaaga ggtgatattg gaaggaaata tcacggctga
    13081 tctaacgatc aacgctgccg acaagaactt catgaaaggc ttcgtatacg tgaaatcagg
    13141 cgctacattg actattgagg ctggttctgt tatcaaaggt gtgtccgtta gtccgggcga
    13201 gaaagccgct tccttgatta tcgagccggg cgctaagatc atcgccgaag gtactgttga
    13261 caaaccgatc gtctttacgt ccgataaaga gccgggtaaa cgtttgacag gtgactgggg
    13321 cggtctgatt atttgtggta acgctcgtgt gaatcgtacc aatcaaccaa ctatcgaagg
    13381 aggacctggt acattatatg gaaatacgac ctccgatgag tttaatgcgg aaagttccgg
    13441 taaattgaaa tacgttcgta tcgagttcgc cggttatcct ttggagccag acaaggaaat
    13501 caatggctta accttcggcg gcgttggtag cggcacagaa gtggagttcg ttcaggtttc
    13561 attttcgaac gatgattctt acgaatggtt cggtggaacg gtaaatgcca aacacttgat
    13621 cgcttacaaa ggctgggatg atgatttcga tacagacttc ggttatacgg gtaaactgca
    13681 attcttgttg agcgtacgtg ataagaatat cgctgatact tcagactcta acggttttga
    13741 atctgataac gacggtgacg gttcttccaa cactccgctt accaagccgg tcttctccaa
    13801 cgtaaccttg ataggtcctt tctatggcaa ggtatccgat aagacacagg ctgaggtgga
    13861 agccaagaca gccgacgctg ctaacggtgc caagggtggt aaattccagg cagccatgca
    13921 cctgcgtcgt aataccagct tgaatgttta caactccgta ttcaccggct ggccttacgg
    13981 acttcgtgct actgataaga aaggtacggc aaacgatggc atcgccatca agaatgtgat
    14041 ctttgctggt atgtggaaga acttctatga ggatgataag gtaagtgaga acttcttcaa
    14101 tcttgccggt agcaacacga ctctggcaac gaccaacgag attatctcta aagatggtga
    14161 ttactcttct gtcgtagctt cagctgtgca aggcgctgaa tttgtcgatg aggtattgaa
    14221 caacagcttc ttcgaaaaag taacttacaa aggtgctttc gacggaaaga atgactggac
    14281 tgccggttgg actaattggg atcctcaaaa taccgaatat taatcaagct tggcattgaa
    14341 taggttgtga atttgttaaa ggcactgagg tatccggaaa gatccctcgg tgtcttttta
    14401 tgtataattt agataagaat gtatcatgaa taaaaagcta ttgttacttt ccgctttttt
    14461 ggcgggagcc tcttggaccg tgctggcgca agacttggta ttgagcgagg gacagtatta
    14521 taccgatgag acacaaacca ccccgtatac gggccgctat acggaattct atgaggatgg
    14581 catgctcaag atggagctgt acctgaagga tggccgtccc gagggaacct atgtgatcta
    14641 ttatccggat ggcaagatcg ccgaggtgcg ttcctactat cacgggatct tccatggtga
    14701 atggcgcacg tatagcgata acggccagct gatcggcctg gcttcttata aggaagggca
    14761 aaaggacggc ccttggcgta tctggagcga taagggaaat ttgttgtatg agatgttcta
    14821 tacggcaggg aagaaatctg gtgtctggcg tagctgggat gaggagggga atctgctttc
    14881 cgaggagaat caataggaat aattgccgtt tacataccgt tgtaacgaca tttacctcta
    14941 atggtaaatg ttttttcctc tagaggtaaa tgtcgttaca tcagtatgta aacagtttta
    15001 cctctaggtg aaaatacttt tacttcttga tgaaaatatt ggtaaatgta attgggtgga
    15061 aatcagcatg cttactcctc atcctcttct ccaaagtcga actcgaaatc gaatccgtca
    15121 tccatgaatt ccggctcagt gaattgctcc agttcacgac ggtctttctt ggtaggacgt
    15181 ccgagacctt tcgcacggtt cacgaaaccg gagatacggt tcatctccag aatctcatac
    15241 tgatccgggg ttgtcacgtt ctccaagtaa ttcgggacga gcttcgcgcc cacacgattc
    15301 tcgatcaatc cgattacctt aaaagagaag gtgatcggcg gtttacgcac ttggatcaca
    15361 tcgccaacct tgatcatgcg ggaaggtttg atcgttactc cacctatcat gatacgccct
    15421 ttcttgcaag cttccgcggc tatcgtgcgg gtcttaaaga tacgggtcgc ccacatccat
    15481 ttatcgatac gtacctcgtt catatctgta ttctcagtct ctttttattt attattaaat
    15541 tgattcatcg taatctggat gccggcgagg cagaagctct tgatgatctc tgtcgcacga
    15601 tccaatatct ctggcatcaa ttgcaattcc tccgggggaa atttccctag cacgtaatcg
    15661 atctgtccgc cccgtggaaa atcgctgcct atgccgaaac gaaggcggga atattcctgc
    15721 gtattcaata actgggcgat attcttcaac ccgttatgcc cggcgtcgct accctttggt
    15781 ttcagacgta aggttccgaa tggcaatgcc agatcatcta cgacaatcaa tagattttcc
    15841 acgggaatgt tctctttttg taaccagtac cgaacggcgt tgccgctgag gttcataaaa
    15901 gtattcggct ttagcacgat caagtcacag tttttcaccc gtatgcgtgc gattgccccg
    15961 tatcgctcct cagtgaaatt gcctcctacg ctctctacca gatggttgac aacccggaaa
    16021 cctatattat gacgggttcc ccaatattcg gaaccgatat taccaagtcc tgttatcaaa
    16081 tatttcatta tcctcgaatc tataaaagaa aggggaagaa cattctatga atatcctccc
    16141 cttcatgtat tgtaataatg tttttacctc agattatcct ttagcctgag caccacgagc
    16201 ggcacgagtc aattgaacgg cgcaaacaac agcgttttta gcgttcatca attcaagacc
    16261 ttcgaagtgc aaagcaccta cctgcatagt cttacctaag ccaaggtgat ctacattaat
    16321 cgtcaacttt tcagggattt gatcgtatat agctttcact ttcagttttc tcatttgaag
    16381 agacaactta ccaccggctt taacaccttc tgcgtgacct tccaaaacaa ccggaacttc
    16441 cattactacg gctttgtcct tagatacttc caagaagtcc atgtgaagga tttcgtcagt
    16501 tacaggttga aactgcatgt ccttaacgat tgccatcgtc ttgttaccgt caatgcttaa
    16561 ctcaacaacg aaaatctccg gagtgtaaac caacttacga acggcttctt ttgtaaccgt
    16621 gaagtgagtt actttttcgc caccgtataa tacagcagga atttcattgt tcttacgcat
    16681 tgctttcaag gctcttttct gatcagcgga acgagcgacg atctctcttc cttttccttc
    16741 taactcaaat gtcttcattt tctttaattt ttgtgttact caaaattagt tattttgctt
    16801 cctaatttcc catcacacgg tacggggcta aaaagcggtg caaagatacg atttttgttt
    16861 gatgtgacaa atatttcgca tgttatttgt cggattatcg atctagcttc actaatttcg
    16921 tggttcgcat gatccaacgg acaaggccgt gggggaggag cattacgagg ggtgtgcata
    16981 ttttgttgaa gagacccggt aatagggaag cccggtggtg aaacaaggca ttaatccctt
    17041 ttttagccag tttttccgga cgcatcatga tacctaggcg gatcgctaag gtctttaagt
    17101 tgtcgcttag gttatataaa ttcgtggcga cggcgccggg acaaagtacg gttacgctta
    17161 ctccataatc cagtaactct gaacgcaagc cccgggagaa acttttcaag tatcgcttgg
    17221 tggaagcgta cagcgtaatt cccggataag gtagccaaca agatagggat gacatattga
    17281 ggatatatcc atgacgccgt ttcttcatct cttgcccaaa ataataacag agctgggtag
    17341 gagtagtcac gtggaggtag agcattttct cgacgatgtt ggccttagct tgtaaggtct
    17401 cgcagaaaaa aaacataccg gcgttattga ccaatacctc tattgggatg tttttctctt
    17461 ggcaagtatc atatagctcc ttggccgccc cggggatcgc caaatcacga taaagcggca
    17521 aaacttctat accatatttc tcggagagaa actcaccttt ctcccggatc gcctgttcct
    17581 cattgctgac gatcactaac tgatagcctc gtgaggctag ttcctcggca taggcgagac
    17641 ctattccgga actggccccc gtgactaaag cccatttctt ttccattatt tatattcaag
    17701 ccttttgatt tcacgtacga tacattccgg aagacctttc acgttcttat gacagaccat
    17761 atcctcgcta tacatacggg cgatacaata gttactatgc ccacaatcgc aacgggcgtg
    17821 ctcgtcttct ttcatacggt tgacgaagcc cggctcgttc accaaggcac gtgccatggc
    17881 cacaaactcg aacccgtcgt tcagtacctc ctcgatcttg tctctggaga ccaatcctcc
    17941 tacgtaaata agaggtaaat gtaaggcttt gcggaatttc aacgcatctt caaggaagta
    18001 agcctcctta aacggttccg agggaatcat atatttaccc accatgcgga ttccaatcgg
    18061 tagatagccc ctaggcatat aatacgccat cgtacggatc ggcatttctc cccgcattac
    18121 atacatgggg gcacggctca cgaatccgcc gcttagtact aaggcatgcg ctccgcattg
    18181 gtcttggagt gtacgggcta cttctaggca ttcgtctatt tcaagtcctc ccttgaaccc
    18241 gtcccgcata ttggtcttta cggttacggc catgtcggaa cctgctgctt tcatcacctc
    18301 ttccatacac attctcatga agcgcatacg gttctcaagg cttcctccat attcgtcttt
    18361 ccggtggttg gtgtacgggg aaaggaattg gctgatcaga taaccatgcc cggcatggat
    18421 ctcgacagcg tccatacctg cctcacgtgc caatcgtacg gcctcaccgt aggcacgagc
    18481 catggaagcg atctcggatt gtctcatacc tcgtacgatc gtgggagagt agaggttgaa
    18541 cccgctggac gctgagatag gcgtgcatcc gcaaatccgc ttatgcgaca tattaccgca
    18601 atggcctaac tggatggaag cggcggctcc ctctttatgg atagcgtcgg tgagcttgcg
    18661 gaggccggga ataatatccg gacgcatcca cagctgacgc tcgaacgaca agccgctttg
    18721 cgtcacggcg gcataagcta tgttcgtcat gccgatccct ccggcggcta cggatgtatg
    18781 atagttgaat aactgctccg agggagcgtt tcccgggcac atactctcga atgcggcggc
    18841 ccggatcgtg cggttcctaa gtgttagcgg accgatctta ccgggtgtaa acaggattga
    18901 tttgtccata tcaatagatt aatatagttg ttccgaaaaa ttaagttaga tagttttctc
    18961 tatattccag acgaaggccc gaagcccttg cgcttccgtt tccttgtcta agttgtgtag
    19021 gatttccaga aaatgatcga ccttctcgtc ttctaccatc gtaaggatag ctgagttcaa
    19081 ggtaggccaa gcgtgattgc cgtaatgtgg ctcgcctgtt ttacttcccc gtccttgcac
    19141 gacatcccaa taggtaaaac ctttaaggtt attacggtcc atgatattga cgatggtctc
    19201 gtaatacgct tgattgaaag atataaatat cgctttcata tagttgcttt tttatgagat
    19261 cgcatacccg tagggaggct tttcttgcga tgggcattca agcctgttta taatgggcat
    19321 cgtaagcacc ttacaatggg cattgtcacg acctaacaat gcccatcgag gtttgcttgg
    19381 cctcggcttc cctatggtac gcaaagataa ttaattattt cgtaatgcct ttcttatttt
    19441 gcggcgtctt cgttttacgc cgttggcggc gaatacggca tagaccgtcg gaacaataat
    19501 caaggtaatc aaggtggata cggaaagacc ccaagccacg gtcataccca tcgagcgcca
    19561 catctcggaa ccctcgccgg ttcccaccgc catcgggatc atacccaaaa cggtcgtcaa
    19621 tgttgtcatc aataccgggc gaagacggga ttttccggca gtcactaccg atgtgataat
    19681 acccatgcca cgttcccgac ataagatcgt atagtcgatc agcacgatac cgtttttaac
    19741 cacgataccc atcaacatga tcacgccgat caaagccata acgcccaatg gtgtctgcgt
    19801 gaccgccaat cccaatacga tacctgtaaa ggcgaacggg atagagaaca tgatcacgaa
    19861 cgggtctacc aacgactcga actgggcagc catcacgatg aataccaaga tgatgatcaa
    19921 taccatcaag atacccaaat cggtaaatgt atcctgctga tcttcgaatg ttccacccaa
    19981 ctgccaactt acgtcggatg ggatatccat ttgtttcaac tcgttccggg cggcggcaac
    20041 caagtcgctc aatgccgctc ccttacccgc tacggcagat acggtgatca cacgctcacg
    20101 gtctttacgc tcgatggtcg ggggagtcat acgttccact accttgccta aatcacggat
    20161 gcggatgcct ttgccctcat tgttatagat caaaatattc tcaagatcct ctacggactc
    20221 acggaactct ggggcgtaac gtaccttgat atcatactca tctccatcct cacgatattt
    20281 tgaagcggtg gaaccattta cacggtttcg gagatacata gaggcggttg ttacgttcag
    20341 cccgttgatg gccagtttct cccggtcgaa gtcgatctgg tattccggga tataatcctc
    20401 acggctgata tttacttgcg agcatccttt tacatttctc atacgacggg cgatctcatt
    20461 cgccacggca tccgtctggg cgaaatcaaa accatagatc tcgatgttaa ccgaggtctc
    20521 tccacccata gaaccttcct gccctccggc gagtacctcg aatttcttga tctcgctgta
    20581 ttgggctaag tcctgccgca tcaactcgca aatctcggta agacctctct cacggtcgcc
    20641 cacgctagtt aggtttatat tgaactcgat aatatgcgta ccgttattgc ttagctgggc
    20701 gaaggtatta tccgtatccg ccgtaccttc cgtgaagtta ctgattagga tctccggata
    20761 tttctcacgg aacttcttgt cgatgtcgag agctaactca cgggtaatat cctgccgtgt
    20821 accgatcggc aactcaatcg ttatgccgat gcgtgcgtta tcttgtgtcg ggaaaaattc
    20881 cgtcttgata accgggatca gcatcatact gccgatgaag atcagcgtag cgcctacgat
    20941 caccgttttc cggtggcgta cggcccagtt caagaagcgt ccgtaaccgc gatccaaagc
    21001 gttcaatccc ttttcgatag gcgtgaagaa catccggtac aatttaccct tctccggttg
    21061 ctggcgtaat aactgtgagc aaagcatcgg ggtcaatgtc aaggcgccta ccgtagaaac
    21121 gatcatgatg atactaacga tccatcccaa ctgcttaaat aagatacccg ccatacccgt
    21181 aaccatcgtc aacggcaaga acaccgctaa catcgtaagg gtggaggcga taaccgagat
    21241 agccacctcg ttcgtggcgt gtacagcggc ctgtttcggc tggctacccc gctcgatatg
    21301 ggtcgttacg ttctccaata ccacgatagc gtcgtccacc accataccga tagcgataga
    21361 aagtgagctc aatgagataa tgtttaacgt attgcccgag gccagcaaat aagcgaaaga
    21421 agcgatcaag gagatcggga tggttaagat aatgataaac gtagccctcc agcgtcccaa
    21481 gaacacgaat accaccaaca taacgatgat aaaggtaatc atgatcgtct ctttcaagct
    21541 atcgatcgta ttcaagatat tcgtggaagt atccatgatt acgtccagct tcacgtctga
    21601 gggtaagcta gcctgtatct ccggaagttt ctggtgtacc ttcttggcga tgttcaccga
    21661 gttcgctccg gactgtttct gtatgacgat cataccacct ttcgtgccgt tgttgaacgt
    21721 ttcttgcgca cgttcctcga tactgtcctc tacacgggcc acgtcacgca gatatacgtt
    21781 ctttccgttc tggctaccga tcactaggtc tagcatctgc ttagcgtccg tgaattctcc
    21841 ttgaacacgc aaggagtagg tattagaacc gatatctacg ctacctcccg gtgtattccg
    21901 gttctcttgc gcgatgatgg tagagatacc ttcgatggtc tggccgtaag cctccaactt
    21961 gtacgggtcg caatacactt gcaactcacg gatcggcgta ccggagatag acacggcacc
    22021 cacgccactg atacgggcca atgggttgga taccttatcg tccaagatct tgtaaagagc
    22081 gttcgtgctc tcctccgcgg tcacggaaag gatcaagata gggatatcgt ccgtaccgaa
    22141 cttgaagatg atcggattct ctacgtcatc gggtagggaa gactctacca tgtccagttt
    22201 gtcgcggaca tcgtttgtgg cgacatcgat atcgatgcca taattaaatt ccaacgttac
    22261 gatcgatata ttctcacggg attgcgacgt gatatgcttc aagtcgctta cgctattcaa
    22321 cacgttttcc aagggcttcg aaacattcat ctcgatatcc gaagcgctgg cgccgggata
    22381 ggccgtcatc accatgatgg tgttcgtctc tatctccgga agcaagtcca ctgataacct
    22441 gcttaaggaa aaaagtccga agatcacgat cgccacaaat acaagggcgg tcgatacggg
    22501 ctttcttacc gctgttccat ataaactcat agtctgttat tcgttttcga tttcaacttc
    22561 cataccgttc gtcaggcggc tttgcccggt gataaccact tggtcgccat cctccactcc
    22621 ggatatgatc tcatatttat cacccatacg gcgtcctagc ttcaccttct ggtaggagac
    22681 cttatcgtct ttgcatacat agatataccg gtcgccggca cctgattgtt ttacgataga
    22741 gcgatccggg gccaccacgt gatccatatg gccgaaactc atcgtcaccc gggcgaacat
    22801 acccggtcgc actcgctcat ccgagttggc gatcttgatc tccacgggga acgtgcgggt
    22861 agcgggatcg atcgtcggat aaaccaagtt gactttaccc ttgaaaacct cgtctccgta
    22921 cacatccagc cggatatcta cctcatggcc tttcttcact ttcgtaaaaa gactctcgga
    22981 gacattcacc attaatttga ccggacggat ttcctccact gtgtagattg ggtttccgcc
    23041 gctgtacata tcgccgctat cgtagttgcg ggcggttacg attccgctga tcgggcttag
    23101 caattgggtg ttctccacca agtttttata cgtctctcga gccacttcca aggaagtctt
    23161 ttgggcatcc caagcggatt tggaagcacc acctacctta tacaactcgt cgatacgttt
    23221 gaactcgatc tcttggttgt ccaattgtat cttcgcttgc tttaggctgg tagcgtccat
    23281 cttggctaat aactgcccgg cttttacatg gtcgcctacc tcggcgaaga ttttctcgat
    23341 acggaatggg gtttggggag cgatattatt tttgatattc gcttccaccg tagcggtaaa
    23401 ttcactgagt tgctccacgt cttgaacaga gaccgtctcc actttcacct ttactttctc
    23461 attctgtgtt tccgtggctt cctcactctt attacccgag caagacatca gcagggccaa
    23521 tgtagctatc ggtattactt tcagcatttg acttgtcttc atataattgt tcctaattat
    23581 tatctattaa actttcaatt tttaattttc aattcatctg ttcgttaccc aatactttct
    23641 ccagatccgc cttcgctacc atatagtcgt agatagattg gttgaagttc aaccgggcct
    23701 gcgtcaaggc aagttcggca tcgttcatct ccagccatgt accggctccg gtgtcgtacc
    23761 gtttttgcga gatcatatat ccccgttccg cttgctcgac ccccttttgg gcggcgtcga
    23821 acttcttgat acaggtattc atattatcta tgtactgttt aacggccaac tgcaaattgc
    23881 gcttggtatc gtcccgttgc aggtttaatt ggtcgatgga gactttcgtc tgctttacct
    23941 tataaaattt actacctccg gagaagatag gaaccgataa cgtgataccg atcatcgaat
    24001 aggggttcca tctgtaattc ttgaacttga agtcattgtt catggcgctc cattgatata
    24061 gaccggtcag cgacaaggtc ggcagataat cgaatttctg catgaccagc gtctttttca
    24121 gctgttccgc ctgaaggtct aattgtttca agtccgtatt ctcggataag gttgtatccg
    24181 tggatagata gtcggcgaag aggctggact tgaaatccgt cagttgtccg tcgcaatcga
    24241 tatttaaatc cagatccatg cccaataacg cttttaactg ccatttagcc aaggtaaggg
    24301 agttctctgc ctgcaacaga ttaggctctg tattctttac cgtcacatcg gcacgtatca
    24361 agtcgtattc agctacggtt ccctgttcat acttccgttt gatatccaga taattctcca
    24421 tggcattgtc gtaactttgc ttgaataccc ggtaagagtc gcttgccaga aggacggcgt
    24481 aaaagctctt tttcacttgg ttcaccatcg ctattttaga agagcgagct tgctccaccg
    24541 ccaattccac gtctaaggcc gagatactca agcttttcca taaggaggcg ttcaccagtg
    24601 gcatggaagc gttgaagccc aagctccagt tgttgctacg tcctacctcg aagccctcgt
    24661 ccatactcga catgtccgtg ccttcgggca agctgccgcc tcccatgtca cccatgtcga
    24721 aatccatata catcacctgt ttcttcaagg tacggttgta gtcccccgca aaactgatct
    24781 gcggaaatag agaagcgtac gagcctttac gtgcgtactt tttcttctgt atttctttat
    24841 cggcaacttt tacggtcggg ttctcgctaa gggcgatctc tagcgctttt ccaagatcca
    24901 gtttcagggt gtcttgagcc agaaccggtc tcgccgccag aaaaggcaat accataaatg
    24961 tgaccaacat catttttcta ctcatcaata atcgtttcat ttaggataga ttttgtctgt
    25021 gattaaactc attaagtgtt cgctataaat cataggattg tttgagatcg aatcggtcta
    25081 ggatcgctct tcccttctcg gtactgatcc ctttcaggaa tgtgaggagg atcgtgttgt
    25141 atacctcggt gatggaatgc ttgcagaaga cattggaagg ccgcaacatc ttcgtctgct
    25201 ctttcaccag taaggccatg atctcgaagt tgatcccctt ttggaacacg ccctctttaa
    25261 cgcctcgtgt gaacaagtcc atacacctct tacccattct cgctttattc atctctattt
    25321 tttgttgggc tttcggatat ttcttcaagt cctcgtaaaa cttctcgttg aaccatctcg
    25381 ggtttttcat catctcctca tagaagagca ggattacttc caaggcattg aaaggttctt
    25441 tttccaatcc tgtcagatat tgtccgagcg attcggtatt gtgatcgatc ccctcgatca
    25501 gcaaggtttc cttgtcctcg aacgactcgt aaagtgtacg cttggagatg ccagccgctt
    25561 tcgctacatc atccatactc acactcttga tgccatattg agaaaaaaga tcgaacgccg
    25621 tattaataat ctgttctttt atcatattct tttttgttac gtcaaaagta gccggggcaa
    25681 tccctgtata caagtaaaaa gcgctgactc gtccgttgga atcgaccaat gaccggatat
    25741 tcccgtcgaa tctattcgca aaggtctgat atatttagaa aaccagaaag gtttatactg
    25801 ttacggtatt ggtatggaat gaaacaggat attgtcaaaa attcttgtta ttcgttcaat
    25861 tttggatgaa aattggttaa aaacgaaata gtgggtggtc tttggctttt tatttctatc
    25921 tttgtccgag gtgataataa aaatctacag atagatatga aaaatttacc tttaattgaa
    25981 gtcactgagt taatcaaggg aattgagtcc agcgacaact ttcaagatga tttatcgata
    26041 gcggatctga acggagattt gattaattac gaggaaaaaa ggctggagca ttccaccccg
    26101 atgcgtttaa atgccttgtt gatgatcttg gtacaggaag gtactgctga tatttcggta
    26161 gactatattc catataagat agagaagaat acgtttataa ccttgatgcc gactcatatc
    26221 atacaggtat cgaaagtgag caaagatttg agagggcgtt tgttgatcgt gtccagatct
    26281 tttctggatg gatatactac cccggcaggg aaaaagaact ctatggtgca ttatatgcag
    26341 atccgtaaga atccatgtgc tgcgatgagt gccgaggaga ctgagcatat atccggccaa
    26401 ttctccatct tacgggaaaa gatgaagctg cgtacccatt ttttccagaa ggaggctctc
    26461 caaaacgcct tagtcggttt ctttatcgag ttggctaata tctttatggg taagaaggag
    26521 ctgatgacgg cacctacact ctcccggaag gaggagcttt tcgagcagtt cctgcaattg
    26581 cttttcgagc attgcaagga gcagcacgtc gttactttct atgccgagaa attatttatt
    26641 accccacagt atctttcgct tatcttgaaa gagctaacgg gtaaatcagc gaataaatgg
    26701 attgacgacg ccttgatcgt cgaggccaag atgctgttga aggccccgca agccacggtt
    26761 cagcaagtag cggatatact ccacttctcc gatcaatcca ctttcggtaa gtttttcaag
    26821 aagcatatgg gtatatcacc catggaatac cggaaatcat aatccggtat tttctatacg
    26881 cttgcggaac ttataccagt tgatcaactc acaagccccg tagaaaatgc tggctacacc
    26941 gaagattacg aatgtatttg ccgccgcccc gaacgggtag gcaagaatca ttactccggt
    27001 tatcaagatc aaagccggca tcaggtagaa ccccaacggt acattgctcc atttccttgc
    27061 ggatatcaat gaaaccaatt gctgtacacc ggcaattacc aataaggctc cgagtaagta
    27121 cattaatata ttcacgaaga actcgggcat gatcaccaac cacgctccga acagtacgct
    27181 tcccgctgcc tcgataggaa acatcggttt ctccccgttc tcgttcttcg gtcgggtgaa
    27241 atagctgagg atagcgaata atcccggtaa aatgaatagt ataccgatcg tgataaccag
    27301 ataggttatg gctgcttccg gccataatac caaaacaaac cctaatacca tcgcgaatgc
    27361 gctacgtaaa accgcgccat taatagatct catatgtttt tattttagat ttcacttata
    27421 atatgacaaa ggtatatatt ctttccgact ttttttacct ttgtgcgcca taaagcagta
    27481 tcaggaaaaa catcgaaata tatccctctt gaatgcatgc ttcgcgtaaa aagacaaact
    27541 tgaaatcatc taacgaataa taatactaaa acaaaaaatg aagcgtatag tttttttgga
    27601 ttacgtgcgt gtgtttgcgt gcttccttgt catggttgtc cacgccagtg aaaactttta
    27661 tggagctgag ggctccacgg atatggtggg accgcaatct tatctggcca atgaggctga
    27721 tcggttgtgg gtagccgtat acgatggttt ctcacgcatg gcggtgccat tgtttataat
    27781 tgtctccgcc tttcttcttg cgccgatgaa ggcagggctg acctcttggc aattctaccg
    27841 tcagcgttgt attcgcatct taccgccgtt tttcatattt atgatactat acagcacttt
    27901 acccttgctg tgggggcaga tagatgccga gacatcattg aaagatatat cgagaatatt
    27961 cttgaacttt ccttcacagg ccggacattt gtggttcatg taccctttga tcagcctcta
    28021 tttatttata cccgtaatat cgccatggtt gaataaagcc acggcgaaag aagagcgttt
    28081 tttcatcggc ttgtttctgt tgtcgacctg tatgccctat ctcaatcgtt gcttcggcga
    28141 ggtgtgggga caatgttttt ggaacgaata ccatatactg tggtacttct ccggttattt
    28201 aggatacctc gtactggcac attatataca tgtccatctt acatggaacc gttctaaacg
    28261 tctggttatc ggaatcgcct cgatggtcgt cggtgccttg ctgacgattt attccttcta
    28321 tgtccaagcg atacccggag taactcttgt cacacctgag atagagatcg gatgggcttt
    28381 ctgtacgatt aactgtgtgc ttcttacggc gggtacgttc ctcgctttta cttgcatagg
    28441 caattcgaaa tctccacgac tcataacaga gatgtctaaa ctcagctacg gtatgtacct
    28501 tatgcatata ttttggctcg gattgtgggt aacggtgttt aagcacgact tagccttgcc
    28561 tactgtcgcc gccataccat gtattgcggt aagtacattt atctgctgtt atgtggcgac
    28621 aaagattatc tcattaatac cgggcagtaa atggattata ggatgaatat aggatagctc
    28681 tgtcatttgg cgcggttact ttgtaaacaa gatgataaga ttacctgtta tttggaaaaa
    28741 atcgtatatt tacgatattc aaataaatcc cgggtaataa tgatgacgag aacagttttt
    28801 atacttttga tatcgagcct ttgtacgcta agttattgta cgccgaggac cgagcctgct
    28861 caaaccgagg tcttaactcc tgtggattct atatcgaagg attccgctgt gatcatggag
    28921 actttgcctc cccatatcga aatagagaaa gagctgcttt acgataagca tactttagaa
    28981 gatacttacc cctataaaga tacgacacgg gagttccagt gggagaaaat gaaagaaaga
    29041 ttatccttat tggagtcgat ccaaaaggag ccgtctcaat gggcgatctt gcagaactat
    29101 aaaaacagga atggagaggc tcctcttgta aaagtcttca agagagatgc ctataagagg
    29161 gtttccgata cgcttggtgt agaacgctat caatccgtcc cgctttattt gctgactgat
    29221 accgtgattc ccgagatcta tggacgtgac ggtagcttgg ttcgtatcaa ggcgatggat
    29281 gaggattcta aattcgctcg tatacaaacc gtgtatgatg gggaggagga gtggtatgct
    29341 ccgaagaaat atatcaagca aataggggat acggtagtct tcgataaggc gatcttcgtg
    29401 gatcgtcata accagaatat cgcgaccttg gagcacgtcg gctcgaaatg gttggttcgt
    29461 agcatgaacc ctgcgactac cggacagcat cgtcctcctt atgcgcagga aaccccgttg
    29521 ggaatgtatg ttctccaaga aaaaaagtct cgcatgatct atttggtaga cggttccaag
    29581 gagacaggtg gattcgctcc ttatgccaac cgttttacga atggggcgta tatccatggc
    29641 gtaccggtca acgctcctcg taaatcgttg atcgaatata gtccttcgtt gggaacgaca
    29701 ccacggtctc atatgtgtgt gagaaacgcg acttcgcatg cgcaatttgt ttacgattgg
    29761 gcgcctgtta atgagacgat tgtttttgta ttagaataaa aatcataact ttgcggcgtt
    29821 attgtttttt agtatgcgaa ggattttctt gtatttgttt tttattgtct tgtctgtagg
    29881 ttcaatttca accggtggcg ttttgcgtgc cctatctccg gaaacgggat caacgtctgt
    29941 ggcggttatg gggcgccaat tatatgagga gatgcgattg gatcaatggg tttgtttcga
    30001 tgcgtttatg caggggctta gaggttccga gaagattgat cggaaaaata aggatatcct
    30061 tacattgatc gatttctcta aaccttctac ggcggagcgt atggttgtat tggatatacg
    30121 gcaaaagaga atactttaca cctctttggt ttctcacggt aagaatagcg gagggaatta
    30181 tgcgacctct ttctcgaacg agaacggttc ccataaaagc tctttaggat tttatctgac
    30241 ggaaaatacg taccaaggcc ggaatggcta ttcgcttatc ctaaatggat tggaaaaagg
    30301 aataaatgat ttggctaagc aaagggcgat tgtaattcat ggcgcctctt attccgatcc
    30361 ttctgtggca gcttcctcgg gtcggttagg acgtagcttt ggttgccctg cgttgcctgt
    30421 atctgtcagt aagccaatta ttaatacgat aaagaatgga acccttttat ttatttacgc
    30481 caacgataag aactatctga cgcaaagttc cattctatcc actcaacaag aaaatgatat
    30541 ttttcatgaa aaaagttacc gaaaagtttt gtagtttaaa ataaaggcgt acctttgcac
    30601 cgcaatcaga gataaacact atgaattgca aaacggggtg tagcgcagtc cggttagcgc
    30661 acctgctttg ggagcagggg gtcccaagtt cgaatcttgg taccccgact tagaaaaagg
    30721 gaaatggttg gtattcaact gttttccttt ttttgtgtcc tgcccttaaa tctaaaggat
    30781 agtcaacgat tgtaatcaaa acaatagttc gtatcttcaa gtaaaaaaca ttcttcttac
    30841 tatatacaaa tatacttact atctcatcta tttccagatt atcgccgtgg aatatataga
    30901 ccacgtcgtg atctgtatat tccacgtctt gatctgtaca gaccacgtcg tggtttgtag
    30961 aattatacag tatgcgcata agaattcata ggctatcgag caagaattca tataggagta
    31021 gagcgttttt tacttaggga gaagaggaga cgctcttacg tgtcaaagtg ggaatagtgt
    31081 caaacaatta gacagcgttg tcaaaatatt ggacagttct aaaagaatag ctttttgtta
    31141 tctggttgtt gtttagttgt ttatgtgttt tggcacgttc tttgctatta tttaggtaga
    31201 aaataataga gcaatgaaac aaatattact tacaacagtt ctttctctca gtttcgctac
    31261 cgcgacggtg gcccaagaga aactttggac tttggatgaa tgtatgcgct atgccgtgga
    31321 aaacagccca tcggttaaaa agcaagttta tacatcagat acgtataagg cggaacggaa
    31381 tgccgccgta gcttcttttt tcccggcggc atcggctaag gtcggagcgc aatatagttt
    31441 tggccgttcg atcgaccctg cgaccaatac ctatgagaat acttctacgt ttaataataa
    31501 ctatggcctc gacgcttcta ttcctatttt tacgggcgga cagctgatca atcaatggtt
    31561 gatggcaaaa tccaatcgcc gtatgggagt taatgacata cagaaagcga aagatgattt
    31621 agcgatgaaa accatgcagg cttatatgga tgtggtgtat tataaaggaa cgattcgtat
    31681 ggcggccgag aaattggagg agagtaaccg taccttatat aagactcgcc ggcaagaaga
    31741 gctgggtttg aaagggaaag cggatgtagc tcaattcgag gctcaagtag cggccgatga
    31801 ttatacattg acccaccagc agaatctttt caataccgcc ttgcttactt tgagggaatg
    31861 tatgaattat ccatctgatt tagaactgga ggtggatact ttattaccgg atatcaatta
    31921 tgtcccggaa gtagagaatg tggcggagat tttcgcctat gcgtccggga ataaccctac
    31981 cgccttgcaa gccgagtatc aattaacgca aagtaaatac caatatcgta tttataaagg
    32041 aaagttgcta ccgagcattt atttgaatgc cggaatctct acgagttatt tcgagaacct
    32101 gaagtctgat aatgccccgg aaggtttcaa ggatcagttt aaaaataacc gtggtgaata
    32161 tgtctctttt agccttagct tccccttatt cgatggtttg agcagattaa cgaacgctcg
    32221 tcgttaccgt aacaatatgc ggatcgcacg ggagacaagg acagaggtct ttcgccagtt
    32281 gcagacagcg gtagagcaat cggtcctgga tcgtgaggga tacgctaaag aggccataca
    32341 gatggataag aaggtgaaat cggatgagtt ggcttatcgt gttaccctac ggaagtacga
    32401 ggaaggcctg atgagcacgc tggatgtaca gacaagtgcg aatacgctgt tggagtccaa
    32461 ggccaatctg cttcaaaagc gattgatgta cttattgaaa agcaagctgg tggattatta
    32521 taagggcaag cctcttatca atgaataaga attgagaaca tagaatttag atgataataa
    32581 aaaatataga atacgatgga tatacaatta gagaaaaaga aaggtcttca gaagaagcat
    32641 attccttatg tagcgggtgg cgtgttgttc gttatcttgt tgggatggat tatctttggt
    32701 gatcatgctt ctacgttgaa agtggatgcg agagggatta gcatcggtaa tgtgacccgt
    32761 gagcaattca atgacttctt tcgtatggat ggtcaggtgc aacctatcac ggtcgtgcag
    32821 cttagccccg aggagggcgg tatcgtacag gagaaagtcg tggaagaggg tgcccaagtg
    32881 aagaaaggcg atatcattgt tcgtctgagc aactcaaatc tagatttgca gatcttgaac
    32941 gctgaggccg agttggcgga gaagcagaac ttccttcgta atacgcaggt taccatggag
    33001 caggataagc tgaccaatca gatggagaaa cttcaatacg atatggacat gaaccgggcc
    33061 cgccgctcgt tcaaccaaca agagcagttg tataaagaga acttgatcgc caaggaggat
    33121 tatctgaaag cgaaggagga cttcgagtta gcctctcaaa agcacgcctt gattaccgag
    33181 cgcttgcgcc aagactctat ctcccgcacg atccagatgg atgagatgga ggccagcttg
    33241 gcgaacatgc ggaagaatat cctgttgatc cgcgaacgta aggaaaactt gaatgtccgt
    33301 tcccagatcg acggtgagtt gggactgttg gatgtcgtat tggggcaaag catcaatccc
    33361 ggacaaaaga tcggccagat taacgacctt tccgattata agatagaggc catgatcgac
    33421 gagcattata tagaccgcgt gaaaccgggc ttaagcgccg ctttcgagcg tcaaggctcg
    33481 tctttcgact taacggtgcg caaagtttat cccgaggttc gtgatggtaa gttccgtacg
    33541 gatttcgttt tcacgggtga gcgtccggat aatatccgta gtggacagac ctactatatc
    33601 aacttggagc tggggcaacc taccgagagt atcattatcc cgaagggaac tttcttccag
    33661 agcacgggcg gaagctggat atttgttctt gatccggatg gaaagaaagc ttacaggcgt
    33721 tctatcaaga tcggccgtca gaacccgcaa tattatgagg ttcttgaagg tctggaagcc
    33781 ggtgagaagg tgattgtgtc cagttatgag agttataagg ataatgaagt gctggtgctg
    33841 gaataaaatc gatataatat gaaaaacata ctaatcgcca ttcgttccat ttttaagaaa
    33901 gggcggcata acgtgatgaa aatcgtatcg ttgggaatcg gcttagcggt aggcttggta
    33961 ttgatcgcta aagtctattt cgaacaatcg tatgatgatt tttatccgga tagagaccgg
    34021 gtctatcaag tctgggcgaa ataccagcaa aatggagggg agttgaagga ttatccgcaa
    34081 acaagcggtg gcatcgctcc aactatgcaa caacagatac ccgagatcga gaccgtcacc
    34141 cgatacacga gttttggaga ctggaccttt acgatgaccg acaccaagat gaaatactcc
    34201 ggtcgttgta tcatagcgga tagttgtttc tttgatattc ttcctcgtcc tatgttgatc
    34261 ggaaatgcga aagaggttct ttccaccccg atgtacgtgt tgatatcaag tcgtatagcg
    34321 aaaaatatcg gaggcgatgt tatcgggaaa aacttcacgg tagacaattc gccgggacgt
    34381 actatgacta ttggtggcgt ttttgaggaa gttccggaaa attctcattc ccgttacgat
    34441 gtaattgttt ccatggcttc ggcgggtcgg ttcatgtggg agggttcgcc tactaatatg
    34501 ttgggaaacg atcgttacat aagctatgtg aagttgcaca agggggtgaa tcctttagct
    34561 ttggaggaac aggtgcgtac gtttgtgaat tcttatttcc ctccagagga acagcaaaag
    34621 gtcgggttaa gcattgattt ctcatttcat aagctagata atctacacaa ggagttgccg
    34681 caagtcaagc gaatgacgtg gatactttcc ttactggcct tcgctttgat ctttacggcg
    34741 gtgatgaact atatcttgat cgtgatatcc tctatcgtaa atcgctcgaa ggaggtggct
    34801 gtccataaat gttatggggc aagcgagaat aatattcatg gtatgatgtt tggtgaggcg
    34861 ttggtacata tagtgctttc actgatcttg gccttattgt tgatccttgc gtttagaggt
    34921 acggtagagg agttgttggc gacttcgtta gattccttgc tcttgtctaa tggtagcttg
    34981 gtcttgctag ggatatgtat cttggtgttt ttcgtatctg gttttatgcc gggatcatta
    35041 tacgcccgga ttccggtggc ctccgctttc cgtaattacc gggagaataa gcgtatctgg
    35101 aagaaagcct tgttgcttgt ccagtttgta gctacgggct ttttggtgac gatgcttgtt
    35161 ttcgttgccc gtcaatatac gtttatggtg aatgatcgtc cgggatatgc ctatgagaac
    35221 cttgcctact gcgggttagc tggcgtggac tctacctctc gtgccaagat tctggatgag
    35281 gtgatgcggc ttccgggagt cgctgcggct accaccgttt atcaattgcc tttcgagcat
    35341 gcttccggta ataatattct tttaccgggc gggactcaag agctttttaa tatcgccgat
    35401 ctctattggg taggcaacgg atatctggac atgatggaga ttcccgtgat ccaaggccgc
    35461 tcgttcacgg agaatgtgac caactcgaga gaggtgatgg tagaccgccg tttcgtggag
    35521 aagatgaaat tggtagcggg ctggacggat gatgttgttg ggaaggatat ttgcgtcacc
    35581 gagcatagca aatggaatga ggagccattc acgatttgcg gcgtgtatga gaatatccgt
    35641 ctgggaggaa tctcgaacca agatatgcgg ccctccgtat tattctatgc gcataagccc
    35701 atgtacacct tgcaggtgaa gttccatgag ctgaccaacg ataatatggc tcgtttacag
    35761 cagaagatat ccgagacatt tccggatcgt gaactgagcg ctatctcttt ccgttccgag
    35821 atcatggatc tatataagga ctcccgccaa ttccgtgatt ccgtgatgat cggaggtttg
    35881 gtcacgcttc ttgttacgtt gataggactt ataggctata cgaatgatga ggtgagccgt
    35941 cgtcgtaagg agatcgccgt ccgccgggtg aatggggggc taccttatgg gatatattga
    36001 ggttgttcat aaaggatatc ggatatatct gtatctatgc ggtcatatta ggcggtggca
    36061 tagcatactt tgtcttgcaa aagtggcaag agcaattcac ggagaaagta cctttgtcat
    36121 ggtacatatt cttgggttgc ggcgtatgtg tcttattgat tatatattcc gtggtttgtc
    36181 tggatgcccg caagacggct aatgataatc cggtgaactg cttgaaatct gagtaattga
    36241 aaatttataa ttcatgaata atttattgaa ctttaagtcc tttttcaagt tcctcggaag
    36301 gaataaggct tatacgctga tagacgtgtt tggtctgtct gtatcgttga tgtttgtgtt
    36361 attgatagcg gtctatacgg tacaggagat gtctacagat aaattccata ccaaggcgga
    36421 tcgtatctat ctggtcggga atgaaaattg gatggccacc ggagccgcca ttccttataa
    36481 gataaaggaa cgctatccgg aggtagaaaa agtttgtccg gtagtggcgg gtaattcgag
    36541 tgatatagtt gtagtttccg gtgatcggaa actgaaggca aacgtgatgt tcgcagactc
    36601 tacgttcttc gatttctttg atttccggtt gctacaaggc actcgtgagc aagcgttggc
    36661 cgccgggaac tatgcggtgg tctcctcttc gttcgcccgt aagatgttcg gaacggatga
    36721 tccgatggga cggaagttgg tggtgggcga taccatatcg gctactataa acggggtggt
    36781 ggaggattta cttcattcct ctattcccga agccgatgtg atcgtgcgtt gggagcaggt
    36841 tcggtatttg aactggtcgt tggctccgga tcaattgggg aatgccggaa gtacatcggc
    36901 ttttgtcttg gtgcgtgagg gtagtgattt cccttctcgt gcggaggata tggcccattg
    36961 gttcaaggaa ttttattggc cgtatcaata tgggacggca aaagaggtac gcatattgcc
    37021 gcttagtgag cagtattttg cgaaagccgc ttcttactct tctttgcgaa agggagattg
    37081 gcgtttcgtg atcgtgctga tgtccgtagg tcttcttatc ttgatttttg cggttatcaa
    37141 ttatattaac ttgacggttg cccaagcggg tttcagggcg aaggagatgg ctacccggcg
    37201 ccttttggga tcttcacggg gtgagttatt catgcgtttg atgctggagt ccactttact
    37261 tacgtttatt tctttgatta tcggggttct ccttgcgctg gcggtcgtgc cgtttgtcaa
    37321 tgatttattg cagacacgtg tcgatatgaa tgtattgggt agacctgtct ggctattggc
    37381 tctggtttca ttaacggttg ccgtgggagt tttatccggc ttactgcctg ctatcattat
    37441 ttcttcttct aaaccgatcg aggtggtaag gggtacgttc cgggctaaga cgaaaatggt
    37501 attcagtaag ttctttatcg tattccaaaa tgtgatcacg atcacgatga tcgccgcctc
    37561 tatcacgatg gtttgtcaga tcgttcatat gatcaacgct cctgtcggat ataaaacgaa
    37621 gaatttattg gctatgcggt cggtggatga aaggcagtta tccgcttttg tcggtgagtt
    37681 gaaaggtttg tcatgcgtag atagggtcgg gaagactcaa ggattgcctt tattcggtag
    37741 taataattgg actgctactt atcaggggca aaatatatct tttcagcaat tcgttatgga
    37801 taaggagtgt tacgatatgc tgggattgga gattttgcgt gataaccatt taacgacaga
    37861 gggctggttc ctaaacgagc aagcgatgcg tgagatgaac ttatcggagg atgcggcctc
    37921 ttttatgctg gacaggcaag aaagaccgat agcgatagcg ggtatcgtcc gggatttcta
    37981 ttgctttgga aatgtgacga cagggatgaa ccctgtcatg ttccgtttct tgaaagataa
    38041 tgaagatcct tggatgatct tgatcgagac acaaggtgat cctttcgccg caaaggaggc
    38101 tatcggtaaa gtatatgaga aagtgaccgg acttgagttt gaggcttact tcatggatga
    38161 gcgtttacaa aactcattcg actcgcaaat ccgtttggca aagatcgtga tcgtattctc
    38221 gataatcgcc atccttattt ctttgctagg cttattggcg atgtccactt actttatcca
    38281 acagcgtttg caagaagtat ccgtacgaaa ggtatttggt tccagcaacc ggcagatatt
    38341 ggttaagctc gtattcacgt tcttgaacta tgtgttgatt gctttcgtga tcgccatacc
    38401 tattattatg tactttatga aagattggct gtccgactat tcgtatcgta tcggtttaag
    38461 tccgctgata tttatcgccg ccggcttatt ctgcctcatg atctcgtttg tctctgtctt
    38521 tttccagagc taccgggctg ccacatcgaa tccggtggat agctttaggc ataggcttta
    38581 attgttaagc atatcataaa aggtaataac gcttgtttaa aaataagggg ggagtaaata
    38641 cagacttttg atacctcccc ttatttattc ttgtctgttt ttctagtcct tcagatcccg
    38701 aacaagaacg gtaacggctt gctgtccttg aaatctttgg tggtgtttcc ggcgtaaatc
    38761 tcgccgtttg tgagcgttag tttcttgata ggtgtacctg ccttgaagtc caagctcttg
    38821 aaatcgaccc aaaagatatc cg
//
LOCUS       DBMDTB010000028        36250 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_472_length_36250_cov_12.722897, whole genome shotgun sequence.
ACCESSION   DBMDTB010000028 DBMDTB010000000
VERSION     DBMDTB010000028.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 36250)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 36250)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36250
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_472_length_36250_cov_12.722897"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(1..2199)
                     /locus_tag="ACZPB4_06540"
                     /pseudo
     CDS             complement(1..2199)
                     /locus_tag="ACZPB4_06540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276640.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase-like regulatory
                     domain-containing protein"
     gene            complement(2196..3074)
                     /locus_tag="ACZPB4_06545"
     CDS             complement(2196..3074)
                     /locus_tag="ACZPB4_06545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GLPGLI family protein"
                     /protein_id="HIR1097912.1"
                     /translation="MKRIIATIGLLCVGLSGAGHETNAQVTINIFNLNDVLRAKPIDE
                     TRFTVQYQTTSMPDTLQPDKKEEETLMLKVGNKCSVYYSYAKFLTDSVLEADKAAGAS
                     QEVINEHLQQYSSKTNAQVYKNYPAGKTTTLDALAASRFRCEEKEERPEWTLLPDTMT
                     ILSYPCRKATCHFKGRHYEAWYTPEIPKSEGPWKLCGLPGLILKAQDSQGHYTFICTG
                     IELSRDKNPILFGGNDFEPISRKNLQKVYERYAADPIGYIALTSPQVKVTVTDDNGKP
                     YQPKNMPYNPIEREER"
     gene            3235..4650
                     /locus_tag="ACZPB4_06550"
     CDS             3235..4650
                     /locus_tag="ACZPB4_06550"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1097913.1"
                     /translation="MGKRIRWIWVISLSAALAAIGVQGYWLFNQFRYEMCTYADEIAG
                     EVFHAGQEEFRIRKEEAEMTKGTYIIERQSKYQSGDSVLNGLKNSFGFQLYPKDTTKI
                     HSFRLHLDPNMPEDSLLVGVDRSVVEFFVPFSAERLDSILSAGLPGLDYRVRPFVAGD
                     TLSGQSSALWLPLSKNLFSTSISICYLFAPIERKAVWVDVDLPMNPLLGRMGWQLFLS
                     IFLILLLLACLGFQIHTIWEQMRLNELREGFVHTMIHELRRPVQTLKVFVSFLNDREM
                     RMDEATTERVLQDSMFELDNLSAYLGKLKDMVCADERETLLRPSAFNLRELVEKVVRL
                     TNIPAGKKVSFSTAFPPDMPDLTADPVHVANVLSNLIENAIKYSGEEVNIDIVVLWNQ
                     QGVELTVSDNGFGIAPDERRKVFEKFYRSSHLPDKQIPGIGLGLSYVRQIVEAHHGSV
                     SLRSELGEGTRITINLPTAAL"
     gene            4647..5330
                     /locus_tag="ACZPB4_06555"
     CDS             4647..5330
                     /locus_tag="ACZPB4_06555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008781043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HIR1097914.1"
                     /translation="MKSTLKILFADDDFKYSLVLKRFLEREGYEVTYTGNGTMALKQF
                     PVVKPDLVLLDINMPGLNGFEVAEKIREQDRHVLIFFLSDRSDKNDRLKGFSLRGNDY
                     LAKPFYPEELIARIKDRFEIGVHENVQEESFHFGNTTFNYTTNEIRTGNNKVLITSRQ
                     ANLLRILATNLNLAVDRDLLLETVWGTSSYANSLALNVQVTYLRKALHNDPSTGIVSL
                     PKKGYMLRG"
     gene            5415..6020
                     /locus_tag="ACZPB4_06560"
     CDS             5415..6020
                     /locus_tag="ACZPB4_06560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007756356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4254 domain-containing protein"
                     /protein_id="HIR1097915.1"
                     /translation="MNFSEQCFRIFEQATEAYHVTDNVDATVHNPYAVKSIEFYLYLK
                     NWIDAVQWHLEDIIRNPEIDPVEALAIKRRIDKSNQDRTDLVELIDSFFLDKYKNVKV
                     LPDATINTESPAWAIDRLSILTLKIYHMREEANRPDATAEHKARCEQKLAVLLEQKKD
                     LSMALDQLLSDIRDGKKYMKIYKQMKMYNDPALNPVLYGKK"
     gene            6020..7075
                     /locus_tag="ACZPB4_06565"
     CDS             6020..7075
                     /locus_tag="ACZPB4_06565"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 9 protein"
                     /protein_id="HIR1097916.1"
                     /translation="MANILVIRLSAIGDVAMTVPVIYSAAKANPTDSFTVLTQAFLIP
                     VFINRPKNVNVIGINTKSTEKTLAGLLRFASALVKYDFDMVLDLHDVLRTMIIRTLFR
                     LNGRRVFVVDKARKDRARLTDAKHKRFKQLRPVIERYADVFRNAGLNYTESFTSLYET
                     SIPDVSALEPLVGAKTGKWIGIAPFAKHRGKIYPTGEMELVMAELSDREDFTIFLFGG
                     RGYEEALLDQWAFEYPRVKSVAGKYSLDQELALISRLDLLICMDSANMHFASLVGTRV
                     LSVWGATHPYAGFYGYHQDPEDCIQLDLPCRPCSVFGQKPCLRKDWACMKQLNPDLII
                     NKVLTSLNEMVSDEGDH"
     gene            7059..7793
                     /locus_tag="ACZPB4_06570"
     CDS             7059..7793
                     /locus_tag="ACZPB4_06570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide kinase InaA family protein"
                     /protein_id="HIR1097917.1"
                     /translation="MKEIINPAYGRFEDFVRRVPRIFSEEGKTIYKARNEIKVFEVDG
                     VELNVKRYRVPLLINRVIYRFFRQPKAVRAYEYALRLVAKGFETPAPIAYVLFREKGL
                     LGYSYFISLQSSYKTLYKVGQRPVEENEDIFRALGTYMAELHEAEVYHADFSPGNVLY
                     DRTEEGVRFSLIDINRMYFGPVSLKRGCANFSRLWGREAAFHLMAETYAESRHFDKAE
                     CLRWILYYRNRFWKKYALKHEIEFEL"
     gene            7800..8663
                     /locus_tag="ACZPB4_06575"
     CDS             7800..8663
                     /locus_tag="ACZPB4_06575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097918.1"
                     /translation="MKIQILRFCLVVSCLLAYVSPVKALEWWEKVEYLTYSPRYFGPN
                     AFPIPELVGGSLSSRWEVELRGEYHKTRGDQTKDIFTRLYIPVVKGRVGVNVSWVFQE
                     WYEMSPEVRDERYAVELKSPIVCRGDVIFNFYFQALRSEKWMDIVVSANLKTASGGRL
                     CDARYTDAASYWFDANLGRTLWKRKDVNASIRVQALAGFYCWMTNDVVNRQNDAFCYG
                     AGVLGTYRGVSLDCNYAGFRGYRDNGDKPMILRTKLNYELKKNILSFQYKHGMKDHLY
                     DSYSLAYIRCF"
     gene            complement(8677..9741)
                     /locus_tag="ACZPB4_06580"
     CDS             complement(8677..9741)
                     /locus_tag="ACZPB4_06580"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HIR1097919.1"
                     /translation="MNILLVYKEADIATYKMLEGLSKLEDFNIYIASPQSYTDKKIYG
                     NCTPLDLPVITSKFNWNVIRALRKIIKTYRIDLIYSPSSSGLSNALFASIGTRAKNIA
                     YRGTQAKLKRFDPTYYLGILNPAVEHVVCETKDIEEYLSRFIARKRLTTSTKPFDIDW
                     IKEAVRTPKQADDIPDDAFRCIYIGATKNRPFKGLTDLIDAFILLDDPRVHLTIVGEY
                     GENDFQLAQQSKVSAQIHFLGQRSDAISFLVTSQLFILPSHRDASPRVVREAMACSVP
                     CIVTDIPGARDLIIDGVTGLLVPPSSPQQMAASIRSLIDNPERLEAFAKASREHIIQD
                     FSVKAYTDGFATLFRSIKKA"
     gene            complement(9765..10898)
                     /locus_tag="ACZPB4_06585"
     CDS             complement(9765..10898)
                     /locus_tag="ACZPB4_06585"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009101 - glycoprotein biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HIR1097920.1"
                     /translation="MKIAFDAKRITHNATGLGNYSRFVVNSLSASFPEHTYQLYTPGK
                     GKEALRKRIEERPNVSFHYPEGRFDKLFPSLWRTSGLTATLRKERVDLFHGLSNEIPM
                     NLKQNGIPAVVTIHDLIFLRYPQLYKPIDRSIYTYKFKQACLRSDKIIAISRQTMRDI
                     RDFFHIPESKIEVVYQGCDPIFGQAVQEDVKSSVREKYQINGPYILYVGSIEERKNLL
                     LLVKALKELKEDISVIAIGKHTPYTDTVETYIRENNLSGRVRILTHIPFNELAAFYQM
                     ATLFVYPSFFEGFGIPILEAQLAGIPVIAATGSCLEEAGGSSALYTDPRNEQELRSLI
                     ESVLNEPKLAESMRSGGRENIRRFMPDVLAAHFMRVYENISQS"
     gene            complement(10955..11590)
                     /locus_tag="ACZPB4_06590"
     CDS             complement(10955..11590)
                     /locus_tag="ACZPB4_06590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease H1 domain-containing protein"
                     /protein_id="HIR1097921.1"
                     /translation="MAKNKFYVVWKGLNPGIYDNWAECKAQVDGQEGAKYKSFENREE
                     AAKAFEAGYTHYLKTASSPKAVARLAPEAPIGNPINESLAVDAACSGNPGDMEYRGVY
                     TATGQEIFHIGPLKEGTNNVGEFLALVHGLALLQQKGSDLPIYSDSRNAISWVKKKKC
                     KTLLERKPINEPIFDLIERAEKWLNTHTYTTRILKWETSVWGEIPADFGRK"
     gene            complement(11577..12374)
                     /locus_tag="ACZPB4_06595"
     CDS             complement(11577..12374)
                     /locus_tag="ACZPB4_06595"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HIR1097922.1"
                     /translation="MILLSFDIEEFDAPLEHGVELPFEEQMRTSVEGTRKILACLARH
                     RVKATFFCTANFALHAKDLILDIQKGGHEIASHGFYHSSFETADLRKSKEALEELTGQ
                     PVNGFRMARMMPVEEEEIHKAGYLYNSSLNPTCIPGRYNHLGQPRTYFMKDGVLQLPA
                     SVTPIVRFPLFWLAYHNLPASLYRKLALWTWKEDGYFLTYFHPWEFTSLSDRKELKLP
                     FIMTNHSGCGMERRLDALIRFFKDKRAPFGTYTQFSQEILSKSHGQE"
     gene            complement(12384..13100)
                     /locus_tag="ACZPB4_06600"
     CDS             complement(12384..13100)
                     /locus_tag="ACZPB4_06600"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HIR1097923.1"
                     /translation="MNARADIDLVLPCYNPPSDWEERVATHFHEVERLFSPVRFHLFI
                     VSDGSRRGYEPETIDRLRQLIPNVCVVDYKPNRGKGYALREAVKRCTSPYIIYTDYDF
                     PYTNDSFGRMVETLLGGADVVVATRSKSYQENLPPFRKVLSKLSHICNTWILRIKIKD
                     TQGGMKGFSQAGQAIFLTTRINSFLFDTEFIYKASRRKEINLRTINANIKEGLAVSDM
                     GFKVLRREALNFLSILFHRD"
     gene            complement(13106..14287)
                     /locus_tag="ACZPB4_06605"
     CDS             complement(13106..14287)
                     /locus_tag="ACZPB4_06605"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 87 protein"
                     /protein_id="HIR1097924.1"
                     /translation="MMKFIDKFNTIIHKPFFSKYSTLMGLWALLGVIAWITKYFPGKY
                     NNFSIFRQSFWHTLNELPLYAAYPEEYNDIFHYGPVFSLVVAPFAITPLWLGLLTWSV
                     AQSLFLFWAVKMLPGIKRERIFIYWFCAHELLTSLFMSQFNISIAAIIVLAYALIEKE
                     KDVWATFVIMLGTFTKLYGITGLAFFFFSRHKMKFSLSCVGWAVVMVVAPMILSGPDY
                     IMSQYTGWFEDLSGKNSENLFALMQNISFLGMVRKISGSVSYSDIYLIIGGLIVFGLP
                     YLRISQYKYEAFRKTLLASVLMFVVLFSTGSESSTYIIAFIGVAIWYTAVPWKRSTLD
                     IVLMVFAFILTSMSPSDLFPKYIRVHYVYPYALKALPCMLIWLKLTFEMCTRSYNPVK
                     V"
     gene            14393..16453
                     /locus_tag="ACZPB4_06610"
     CDS             14393..16453
                     /locus_tag="ACZPB4_06610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NHL repeat-containing protein"
                     /protein_id="HIR1097925.1"
                     /translation="MNEMLRYTIIRVILFVMGGFLVLGCSDEDDVGNSGGTSKYGLIR
                     MAEEDYDSSNTSYILQDEEPDEVLFDSSKRKFKVNEPLQVSVTGQKELMLRFYSPRAI
                     HNVIVWATVEGYEDEVRFAEFTTVLPFQEFKMKLPFLERAKVYYTRSGEEVTIDAHPD
                     IVAENISLRVECGDPVYQGMINVKPKWDIWFGKYSGSNWGNFRPHLAREAVALSLNMA
                     AMFSSSLFDEELEKWRGKLINNEQIVDIDVLKKQITNHGGLCYGRVVNVVGLGGGNTF
                     GLGEYVYLTHYADDANGSDTPYHELAHCLGYGHSGNMTYYPAEGGFPTICMKVYSQLS
                     VSKKLPVYSRRFLHTRRNKNLVENKNVYTSSKYIIDDPELDAIDGGLGLAPMETDRAG
                     DEGSPLSFTLSVLDIPGATVETFHPKAVHLYGNTLYVANDAPGHYSLEVFDVSSGNVR
                     HVKSMVEWMNGDKKETFAGEPNGVTRSYGKIYVTNTGSRTDVFDAETYEFITCIGTGT
                     WGEGGYQTVHAFDVTASQGAVFIRDKRKLVVVLEQDVQPGSAARVPIYSRSVNLQEAM
                     GTYAVAARNDGFLYVTAQNKNIIYLFDPADIRAGDTGFAPYLVTLGFEKSPQSIAFVG
                     DRLFVTLRVDDKRSELWEISPKNGKLLQDFTDSMVYPEKIAGARHTLLVVDRATQTVK
                     AIGL"
     gene            16534..17055
                     /locus_tag="ACZPB4_06615"
     CDS             16534..17055
                     /locus_tag="ACZPB4_06615"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HIR1097926.1"
                     /translation="MKRVFLVGYMGAGKTTVGKELAKLAGLSFIDLDYYIEGRYHKAV
                     SQIFAERGEEAFREIERNMLHEVAEFEDVLISTGGGAPCFFDNMEFMNASGTTVYLKV
                     SVEELAKRLELCKHTRPVLKGRSGEELRAFIAESLEKRNPFYTKASITFDAEKMLTES
                     DVHDISNALMKIL"
     gene            17059..18270
                     /locus_tag="ACZPB4_06620"
     CDS             17059..18270
                     /locus_tag="ACZPB4_06620"
                     /EC_number="1.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008781049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000286 - alanine dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0042853 - L-alanine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
                     /protein_id="HIR1097927.1"
                     /translation="MEANDGRQAQGAYIPQELLKEISKVNNRLLIGIPRERCEAEKRL
                     PLTPEAVDMLTDCGHRVLVESGAGLGINYSDNHFSEAGAEIVDTPAEVFQADLILKIL
                     PPLPVEIAFMRPRTTVFSLVQFNLFAQEAFELMMAKRITAISYELMADEYNRFPVLNV
                     TSEIEGAASITIASELLSNTQGGKGILLGGIPGVSPTEVVIIGAGNAGTVAARAALAL
                     GASVKVFDDDINKLRIIQQVLGQGLFTSTFHPNVLHNAFRSADVVIGAMRYINTRHRY
                     IIATDLVRTMKKGALVIDLRVSQGGCFETTCCLSREDPAVFEQYGVLHYCKLNISNRV
                     ARTTSMAYSNIFVPLLLSLGDAGSVQGMIKSDKGFRAGVYMYYGKTVNSYVSNHFNLS
                     SNNLDLYLSAF"
     gene            18359..20212
                     /locus_tag="ACZPB4_06625"
     CDS             18359..20212
                     /locus_tag="ACZPB4_06625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase subunit alpha"
                     /protein_id="HIR1097928.1"
                     /translation="MAEQTKVKTLEKVVIRFSGDSGDGMQLTGTIFSNLSAVFGNEIS
                     TFPDYPAEVRAPQGTLSGVSGFQVHLGSRKIFTPGDKADVLVAMNPAALKVNVKHLKP
                     NAIVLIDTDSFKKSDLDKALFTTDDPFTELGLTGVQVVAAPISTMVKDGLVEFGLDNK
                     SALRCKNMFALGLVCWLFERPLEEAMHMLQNKFAKKPVIAQANIKALTDGYNYGNNIH
                     ASVSTYRIESKKAEPGFYTDVNGNKATSYGLIAAAEKAGLQLFLGSYPITPATDILHE
                     LSKRKDLGVITVQAEDEIAGICTSIGASFAGCLAATSTSGPGLALKSEAIGLAVIAEL
                     PLVIIDVQRGGPSTGLPTKSEQTDLMQALYGRNGESPAVVIAASTPTDCFDAAFWAGK
                     LAVEHMTPVILLTDAFIANGSSAWRIPEMDKYPEIKPNYVANYQDEKVWKAYRRNKES
                     LVRYWAIPGTEGFAHRLGGLEKDYETSAISTDPANHQKMVTTRQAKIDKIADYIPELE
                     VIGDEDADLLIVGWGGTYGHLYETMETMQENGKKVAFAHFKFINPLPKNTAEVLSKYK
                     KVVVAEQNNGQFANYLRGKVPGFNPYRFNRVKGQPFVVARLVEEFTKILEA"
     gene            20216..21232
                     /locus_tag="ACZPB4_06630"
     CDS             20216..21232
                     /locus_tag="ACZPB4_06630"
                     /EC_number="1.2.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:ferredoxin oxidoreductase subunit
                     beta"
                     /protein_id="HIR1097929.1"
                     /translation="MTTEETKFQPKDYKSDQYVRWCPGCGDHAVLNCLHKAMAEVGVA
                     PHNMAVISGIGCSSRLPYYMNTYGFHTIHGRGAAIATGVKTARPDLSVWLITGDGDCL
                     AIGGNHFIHAVRRNIDLNIVLFNNKIYGLTKGQYSPTSDRGFVSKSSPYGTVEDPFIP
                     AELALGARGNFFARTIDVDLKNTTEVLTASARHKGASVTEVLVNCVIFNDGIHKGIVD
                     KEYRADRTIFLRHGEKMVYGANMDKGLVLDGLKLKSVTIGQDGYTMDDVLVHDAHEKD
                     NTLHMMLAMMSGDMPIALGVIRDVEGPTYDEAVHQQIEEVQAKNPTRKLHDLLMKGEI
                     WEVK"
     gene            21647..23254
                     /gene="pckA"
                     /locus_tag="ACZPB4_06635"
     CDS             21647..23254
                     /gene="pckA"
                     /locus_tag="ACZPB4_06635"
                     /EC_number="4.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016274536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004612 - phosphoenolpyruvate
                     carboxykinase (ATP) activity [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HIR1097930.1"
                     /translation="MANLDLSKYGIVDVKEIVHNPSYDVLFAEETKPSLEGFEKGQVT
                     ELGAVNVMTGIYTGRSPKDKFFVKNEASEDSVWWTSDEYKNDNKPCSEAAWADLKAKA
                     VKELSGKRLFVVDTFCGANEATRLKVRFIMEVAWQAHFVTNMFIRPTAEELANYGEPD
                     FVSFNAAKAKVDNYKELGLNSETATVFNLKTKEQVILNTWYGGEMKKGIFSIMNYLNP
                     LRGIASMHCSANTDKEGKSSAIFFGLSGTGKTTLSTDPKRLLIGDDEHGWDNEGVFNY
                     EGGCYAKVINLDKESEPDIYNAIKRDALLENVTVAADGKIDFADKSVTENTRVSYPIY
                     HIENIVKPVSKGPHAKQVIFLSADAFGVLPPVSILTPEQTQYYFLSGFTAKLAGTERG
                     ITEPTPTFSACFGAAFLSLHPTKYGEELVKKMEMTGAKAYLVNTGWNGSGKRISIKDT
                     RGIIDAILDGSINEAPTKKIPYFDFEVPTALPGVDPKILDPRDTYADPAQWDEKAKDL
                     AARFQKNFAKFTGNEAGKALVAAGPQL"
     gene            23444..24544
                     /locus_tag="ACZPB4_06640"
     CDS             23444..24544
                     /locus_tag="ACZPB4_06640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016209 - antioxidant activity [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin domain-containing protein"
                     /protein_id="HIR1097931.1"
                     /translation="MIKKLALIIGFIICLSSCGKDYVYRIEGELSNLEDQTVYAVFEK
                     DNYKVVDTVACTKPGQFQIDQNEAGFHCVTIFFADKEHWVTAYLEPGETVKITGDANS
                     PLLLQVKGGRTNDKLTAFKKKIAPLLTELTNLSNSLNSKDLNDTIEETDIAARLANVN
                     MQLSEEAIRYVKENPDEEASVVLIQSFFSDPDDTRKIDELLALLNPRLKDFYLVKELE
                     QYSARAKRTALGAEAPDFSVRNIYGNTVSLDSFPQKYLLLTFTAPWCDMCQTEDLYLD
                     KVAMKYPKDQLDILLVSLDDNPDNVRDVLKKDSIAWNLVTDSAGQAAMLIDLYNVSVL
                     PRCFLIDEDHKILMKTENGIEIKQTLENLFED"
     gene            24605..26143
                     /locus_tag="ACZPB4_06645"
     CDS             24605..26143
                     /locus_tag="ACZPB4_06645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YifB family Mg chelatase-like AAA ATPase"
                     /protein_id="HIR1097932.1"
                     /translation="MLVKSYAAAVQGISATVVTVEVNCSKGIQFFLVGLPDVAVRESH
                     ERIISALQVCDYKFPRNRIVINMAPADIRKEGSSYDLPLAIGILAAAEQIDSSNLSKF
                     VLMGELSMDGSLQPIKGALPIAIKAREEGFKGFILPKQNACEAAVVNDLEVYGASNIK
                     EVLEFMEGKPTLRPTVIDTRKEFYDRQQLFDCDFSDVRGQENVKRAMEVAAAGGHNLI
                     MVGPPGSGKSMLAKRLPTILPPFTLHESLETTKIHSVAGKIGGGTSLMVQRPFRSPHH
                     TISNVAMVGGGTFPQPGEISLAHNGVLFLDELPEFNRSVLEVMRQPLEDRVINISRAR
                     FTVEYPAGFMLVASMNPCPCGYYNHPDRPCLCSPGAVQKYMNRISGPLLDRIDIQIEI
                     VPVPFEKISEQQPSEPSIAIRERVIKARAIQERRFAAYEGIYCNAQMNSKLLHQYAVP
                     DASGLSILKTAMQRLCLSARAYDRILKVSRTIADLDNSEHIEVRHLAEAIQYRSLDRE
                     NWGM"
     gene            complement(26437..27285)
                     /locus_tag="ACZPB4_06650"
     CDS             complement(26437..27285)
                     /locus_tag="ACZPB4_06650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005645426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIR1097933.1"
                     /translation="MENDIPKIDLPQDWVIGKLSIEDIGLLNLYANYPCRLKAGIFVL
                     CLGGEIEASINLTQLKVEPGSFITIMPGSILQIHRADGDLQIYFMGFSSDFLSQANSS
                     KAVIDMHYIVKDNPVYKLKEKAQPLMKDYFELLLKTYEFYATKINRGITNHLFTGMLM
                     GISSMYKDQTEDLSMLSKAELISKNFTQLVMQNYTMQRSVAWYAKRLGITQAHLSTIV
                     KQSTGKTCIEIITSMVIMDAKAQLKSTNLTIHDIAYTLNFTNMSFFGKYFKRHVGMSP
                     QEYRNS"
     gene            28248..29030
                     /locus_tag="ACZPB4_06655"
     CDS             28248..29030
                     /locus_tag="ACZPB4_06655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4493 domain-containing protein"
                     /protein_id="HIR1097934.1"
                     /translation="MRKKNFTSMGMACLLGCCLMLGSCSSEVDNLDIPKGKGFVKIDL
                     APEVGFQTKAVDESEYKDVNNYTVQVFKSGQEENLIINDLYKNLEEKYSLNVGNYVLK
                     AFTGEDKPVSSDVLYFSGEAAFEVKEGKEVTAPVICKPSSARINVVFDPKMDEYFSDY
                     SLKIETEAQKPSSFVWAKATVGPMYFKVGNQEKVQVTVSLTKKENVKAEGTVKTYTLS
                     PADALKLTLKPVVNNGNLGISITIEETTVDHPVDIVIPGDWV"
     gene            29064..30350
                     /locus_tag="ACZPB4_06660"
     CDS             29064..30350
                     /locus_tag="ACZPB4_06660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4493 domain-containing protein"
                     /protein_id="HIR1097935.1"
                     /translation="MKAINIWMLSTVLFSGLMSCEMKEEIFGKEIPKETGYLTLDVSA
                     GSSASLATKGATDQKEDFPLVIKAMDFDLTKNYESFAKFKEENANGVIELPKGNYEIE
                     AHSPGEFAEKMYDPYYGGVEKAEIMPSVEKTATVKCKIQNVKIAMDFTSEFINYYSKW
                     SITVDDKCGHSDIYTQENPNPTPIYWKMAAETDKIYVSGTAIVKETSEEVIINQTLTK
                     KESADFVESDSPYFVGGDGLAISLAPGKEVDLNKTGITITVNGFNQETNENIDIEVEG
                     DSGEENPEPPTPPVTGDDPTITIPQALYTLPADEQKNANVIISTPAGLKNITVAIKGG
                     NELFASIVKDLFGEEFKLIGNEALGETLTSMGVTLPVGGEKSYEFPVHAFFSLLLDPS
                     TGGGVTTDPEGHVFNITVEDNDGKVVKDKLSVKVAE"
     gene            30352..32151
                     /locus_tag="ACZPB4_06665"
     CDS             30352..32151
                     /locus_tag="ACZPB4_06665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4493 domain-containing protein"
                     /protein_id="HIR1097936.1"
                     /translation="MKTIYTLLFFVLVLGLVACQAEDDTSMKNTGYLSMDITTNNSTA
                     TKAGSEEVVYNPKQLAVQILNDQGGVVKETDDYTAWDGERFSLPTGKYVVKASSNGFD
                     GKAAEFDKPYYVGSAEVEVMAGKDVTAEVICTLANVLVTVEFDELFKKSFKSATIVVA
                     DSADQTGTRLTFELGKNETAKAYFPVPEKSLIISTSVTNQKGTLHSKKDTVRAVKARD
                     NVRLMYKVADSPNGSTSIDITLDGTIKTYNFTIGVPLTAKTTLSASAANAWSSFAYLE
                     GKVLSKAGVLDQSKLAMEYKLATDEAWTPVAYLTVGENDTYSVRITGLTPATKYQYRF
                     IYKDTEEVASEIVEFTTEAAIALYNANFDLWYQNGKTWYAGESGKSFWDTSNPGTTTG
                     LGAIVNINPTQGSSAVVHTSGGKSAELKSQFKVKFAAASLYTGSFGGLVGMNGAKINF
                     GQPFASRPTALKGWFQYAPVNVTHVGDNLPADAVVEKGDPDVCSIYIAMSKKQYTIDN
                     TKMAETAIDFENDANIIAYGEVPVSECVSTNGQWKEFNILLKYKNLTEKPTHIIVVCS
                     SSKYGDYFTGGDGSIMYLDDFSLIYDDEPTMWK"
     gene            32311..33060
                     /locus_tag="ACZPB4_06670"
     CDS             32311..33060
                     /locus_tag="ACZPB4_06670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097937.1"
                     /translation="MSRKLFTLLLLLAIVTGTVNAQRGKRTIKRIDREVQEAVFIPKG
                     TWMAGGAVSYSEHDESNLNFLVIKDLEGNGYNFAISPYVGYFFRDNISAGVRFAYRRN
                     YLDLGNVDANLGDITISFKDLYYLEHKYETSGFLRTYIPIGKSKIFGLFNEARVTYGY
                     GTGKNSTGSGANYDGTYQKVQNLQIGFAPGLAAFITDWSAVEVSVGVMGFDFKWIDQT
                     TNQVEQGSSRTSSGNFKINLFSINIGMTFYL"
     gene            33067..34773
                     /locus_tag="ACZPB4_06675"
     CDS             33067..34773
                     /locus_tag="ACZPB4_06675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PCMD domain-containing protein"
                     /protein_id="HIR1097938.1"
                     /translation="MRIINDIYKVTCRFCLFVFFVLVSCAIENDIPYPIVNAGITDIR
                     VEGQRPAEGSSDDAALIDASAKTILLYVNDSADISRLKLTRLVVNPRNAQVLVDSTLC
                     ANPNKFPFAGFASLDSIPMSSNTRVDFTKPVNFTIKTYQDYVWQVKVKQIIDRKVEAK
                     GMIDYSIDELDNRVIIYVGKGENLKNISITSLALGGAYGEVTPNPTTVKDFTSPQKFL
                     VQYPWSEPNKGTIWTVYVRLTDEEGGSQPSAGDLSVNTWSKYAFVEGKATEANCSFEY
                     VKQGETSWNMVSAKANGSKVSAKIEGLQPATAYQCRLVDASGSVLGESTFTTETATPL
                     YNGNFDLWHQDGKTWYAGEAGHSFWDTSNPGTTTGLGAVVNINPTQGNSTVVHTPGGK
                     SAELKSQFKVKFAAASLYTGSFGSLVGMNGAKIKFGRSFASRPFALHGFFQYAPVAVT
                     HIGDNQPAGTLSKGDMDVCSIYIALAKKQYTVDNTDTDTFIDFKGDNNIIAYGEVPVK
                     ECVSTNGAWKEFTINLEYKTQEKPGDMHLIIVASASKYGDYFTGGDGSVLYVDDFELI
                     YD"
     gene            34779..>36250
                     /locus_tag="ACZPB4_06680"
     CDS             34779..>36250
                     /locus_tag="ACZPB4_06680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008781056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4493 domain-containing protein"
                     /protein_id="HIR1097939.1"
                     /translation="MMKQIDKFCCCIFSLFLMMACQEEEIMDKTAGFQVSLQDMGVAI
                     ETKSTPAELGKPLADQFKLKVVKNGDSSPLFDGNYTSQTIPASAGTYTISASYGDNPV
                     LALDAPYYLGDTTNVVIKEGEQKKITLSCKVANALASASFPTDTELKKIFSSYWVKVV
                     VGKSSCKLTSDSKKSAYFQAEKQVAFYFEGTKVSGKDFSEELKHKDLPSVLKAGHHVK
                     LTLKLSDDLLLDVAKVEIKKETITSDIPMDWLPKPKVEAEGFENNILSFAETETKTAI
                     LNLNTASALQDLKLKFTFGDPQFSSLNDKDYLLSVPADKAEMENVLGIVLPEIGVDKA
                     SLDLTSIVAKLRTDAGTTVENKIEVDVRANNRWSSEEIKGQENPSRVYTLRCNKPEMA
                     VSVQPGNIWTKEFTIDELTVTTGDPEVIKSKLKYQYKEKSGGDDTWKDIQDMKVLFNE
                     HPQNRSYQVRAVYRDVVMTDAIDVELENPVQLPNSGMEEW"
BASE COUNT         9435 a         7282 c         9398 g        10135 t
ORIGIN      
        1 ttcctccgta ccggatatcg gtttggtaac tggtttccca atggcggttg ggagtccaga
       61 tcactttggg ctctaggcgc atgaggcgat attgataagg aagcctttgt cccccgctga
      121 tttgctcggc cttgctgata ttgaggagcg ccatgagcga ggtctttagc cctagatcgt
      181 aaaagccttt ggatagcgtg cttttgacgg tatagccgga accgtggttg gacagcggta
      241 aggagactcg ttgtacctgt ccgttctcta tacgttgctc gtatatacga ttgtaccact
      301 cccggttgtg tgtcaggttt accgtggcga agaattcccg tgccgtactc ttgtattccc
      361 cataaacgga ataaagctgt tgtctgtaaa ccgggaggat tccgcaattc cagacgctat
      421 tccggtaatc cgtttgataa ggccggtcgt ataagtcggt catctctcca tatctttcct
      481 tataggaggc gtgtaccgtg aaacgccatg cgtaattcag tttgtagata atagataggg
      541 acggattaac cgagatgcgg gagaaaccga cccctgtata tccggtccat ctgagtgggg
      601 agctgaggga tagggtccat ttataggtat tccattggta atcgggtgag agataagttt
      661 gcaggctttt cttgatattg ctgatctccc cgtttatgcc caccgtatat cgctgggtga
      721 gggaaccgct ctttttcagg aatgaaaagg aattatcggt ataaaagtcg cgtaagctca
      781 ttggataagg gtggttatcc aaccgaagat cggccgcgtt gctgtggtaa cggagcaaag
      841 actggacttc caacgtgtat ttgtccaagc tccacaggct ccgtaaatta ttacgcaagt
      901 tgaggttcgg ggttttgatg cgttggtcca atgttgtacg gccggtggaa attgtgtttc
      961 cggttatatg ggaaaggctg gattgccaat ctccggtggc tgagaactgg ttcttgagat
     1021 acctttcctg cgagttgttt tccactccga tattgaggtt ggcttgatcc gagcgaatgc
     1081 ggctatcgct ttgttccgtt agatgaatcg tgtcctcgga ttggtaataa gtcgtctcac
     1141 tccccctttc ctgtgttcgc aggtcgtgga tataaccggc gtttatacgg agttgggtgt
     1201 tctcgttcag tttatatagg cgatttgcgg ataggctgtg tatatggttg aacagccagc
     1261 gctctttctt tagcggggcg gaaaatgagg gctgtagcag aaattgggga accttgggct
     1321 cggataaacg ggattcgggt gattcggtaa gcgtattttg ctcgcccgat acatcctgcc
     1381 cggtattatt ccctttatat agataagcgg attggctgct gcggctgatc tgcaaggcgt
     1441 cagcggctcc tttccataag aacggggatg cgccgagacc gccttcggca ttgatcagcc
     1501 agcgatcccg gaattccggt ctcagtttga ggttcaacgc tacgtcttcg gtcttgatct
     1561 ttctctgtaa cacacggatc ggttggtggt tctccatcac ttgtatgttc tgtacggcgt
     1621 cggctcgcag gttctcgctg atttgcttgt atttcccgtt ggtgagatcc agtccctcca
     1681 catagaaatt acggatctct ttcccgttgt aagagatctt ccccagatca tcgatatcga
     1741 tacccggaag tttccgtaat acgtccttga tggattgatc ctttggggag agaaagcggg
     1801 tgacatcata attgatcgta tcttgctgcc ccagacacgt cccggacgga tttccacctc
     1861 ctttaggctg aatacctgcg gctccatctc aaaacgaagc gtttgtccgg catgtacggc
     1921 ttgttgctgg gtttggtacc ctaagagcga gacggagacg agaagtgagt ccgtccgctt
     1981 cggttgggtg agggtaaagg tcccttcatt attacttaac gtatagttga tcggaaggga
     2041 gacgttgcct ctagttaatt gcacggtggc cgcttctacc ggcagttggc tttccctgtc
     2101 gatcacgatc cctcggatga cggattgggc ggccaatcct gccgggcaga gcagcgtaag
     2161 taaacaaaaa gtgtgtatat gcagtatgat ccgtttcatc tttcttccct ttctataggg
     2221 ttatacggca tgttcttggg ttggtaaggt ttcccgttat cgtcggtgac ggtcactttc
     2281 acctgtggcg aggtcaaggc gatgtatccg ataggatcgg cggcatatcg ttcgtaaacc
     2341 ttttgcaggt tcttgcggct gatcggctcg aaatcgtttc ccccgaaaag gatcgggttc
     2401 ttatcccggc tcagttcgat acccgtgcag atgaaagtgt aatgtccttg gctgtcttgg
     2461 gcttttagga tcaggcccgg taatccgcat aatttccaag gaccctcgct tttcggtatc
     2521 tccggcgtgt accaagcctc ataatgcctg cccttgaaat gacaggtcgc tttccggcaa
     2581 ggataggaca ggatggtcat cgtatcgggc agtaaggtcc attccgggcg ctcctccttt
     2641 tcctcgcagc gaaagcgact ggcggcaagg gcatccaagg tcgtggtctt tcccgccgga
     2701 taattcttgt agacctgcgc gttggtcttg gatgaatatt gttgcaggtg ttcattgatg
     2761 acttcttgtg aggctccggc ggctttgtcg gcctctagta cggaatcggt gaggaatttg
     2821 gcgtaactat agtaaacgga gcatttattc ccgaccttca gcatgagggt ctcttcctct
     2881 ttcttgtcgg gttggagcgt gtccggcatg gacgtggttt ggtattgtac cgtgaaacgt
     2941 gtctcgtcga tgggcttggc tcttagtacg tcgtttaggt tgaagatgtt gattgtcact
     3001 tgggcgttcg tctcgtgtcc cgcccctgac agacctacgc aaagcaggcc gattgtcgct
     3061 atgattcgtt tcatgatctg ttggttttag aagttatttg tcgcaaatgt aagagaggaa
     3121 cgtttgccgt aaggaagatt tttattactg aaatattact ccgcttataa aaatggctac
     3181 atgtacgttg taatcatgga gtagctatct atctttgccg gaaaggaatg agacatggga
     3241 aagaggattc gatggatatg ggtaatctcg ttgtcggcgg ctttggcggc gatcggggta
     3301 caaggctatt ggctgttcaa tcagttccgg tacgagatgt gtacttatgc ggatgagatc
     3361 gccggtgagg tatttcatgc cgggcaggag gaatttcgta tacggaagga agaggcggag
     3421 atgacgaaag gtacttatat catagaacgc cagtcgaaat accagtctgg tgatagcgtg
     3481 ttaaatgggt tgaaaaactc gttcggtttc cagctttatc ccaaggatac gacaaagatc
     3541 catagttttc ggcttcatct ggacccgaat atgccggaag atagcttatt ggttggggta
     3601 gatcgttcgg tcgtggagtt ctttgtgcct ttctccgcgg agcgtttgga ctccatcttg
     3661 tctgccggtc tgcccggtct ggattatcgg gtacgtccgt tcgtagcggg cgataccttg
     3721 tccgggcagt cgtcggcctt atggttgccg ttatcgaaaa acctgttttc aacctctatc
     3781 tcgatatgct atttgttcgc cccgatcgag agaaaggcgg tgtgggtgga tgtggatctt
     3841 cccatgaatc cgttattggg ccggatggga tggcagcttt tcctaagtat tttccttatc
     3901 ttgttattgc tggcttgttt gggtttccag atccatacga tctgggagca aatgcgcttg
     3961 aacgagttgc gtgagggatt cgtgcatacg atgatccatg agctgaggcg accggtacaa
     4021 accttgaagg tattcgtctc tttcttgaat gaccgggaga tgcggatgga tgaggccacg
     4081 acggaacggg tccttcaaga ctccatgttc gagttggata atctttccgc ctatctggga
     4141 aaattgaaag atatggtctg tgcggacgag cgggagacgc tcttgagacc ttccgctttt
     4201 aatctccgtg agttggtgga gaaggtggta cgcctgacca atatccccgc cgggaaaaaa
     4261 gtctctttct cgacggcctt tcccccggat atgccggatc tgacggccga tccggtacat
     4321 gtggcgaatg tcttgtctaa cttgatagag aatgcgatca aatattcggg agaggaagtg
     4381 aatatcgata tcgtagtgct ttggaatcag caaggggtgg aattgaccgt ttcggataat
     4441 ggcttcggta tcgctccgga tgagcggcga aaggtattcg agaagtttta ccgttcgtct
     4501 catctgcctg ataagcaaat tcccggtatt gggttgggat tgagctacgt tcgccaaata
     4561 gtagaggcgc atcatggttc agtatccctg cgaagtgaat taggtgaagg cactcgaatt
     4621 actataaatc taccgactgc agctttatga aatcgacatt gaaaatactt ttcgctgacg
     4681 atgactttaa gtattccctc gtcttgaagc gattcttgga acgggagggg tatgaggtga
     4741 cttataccgg caatggtacc atggctttga agcaattccc ggtagtgaaa ccggatctgg
     4801 tcttgctgga tatcaacatg cccggcctaa acggtttcga ggtagcggaa aagatccgtg
     4861 agcaagaccg tcatgtcttg atctttttcc tttccgaccg ttccgataag aacgaccgtt
     4921 tgaaaggttt tagcttgcgc ggaaacgatt acttggcgaa acccttctat ccggaagagc
     4981 tgatcgcccg tatcaaggac cgttttgaga tcggtgtcca tgaaaacgtg caggaggaga
     5041 gcttccattt cggaaacacg accttcaact ataccacgaa tgagatccgt acgggcaata
     5101 acaaggtatt gatcacttcc cgccaagcga atcttctgcg aatcctggcg acaaacctga
     5161 atctggcggt ggatcgtgac cttctgttgg aaaccgtctg gggaactagc tcatacgcca
     5221 actccctggc cttgaatgtg caggtcacct atctccgtaa agcgcttcat aacgatccgt
     5281 ctaccggcat cgtatccttg ccgaagaaag gatatatgct aagaggatag aatttatccg
     5341 gtagaattgg gtttctgatc cgtaagcatt atctttgtcc cacaaagtat tcacagaaag
     5401 aaaatgaatc atatatgaac ttcagcgaac aatgtttccg catttttgag caagctacgg
     5461 aggcttatca tgtaactgac aatgtagatg ctacagtgca taatccctat gcggtaaaga
     5521 gcatcgagtt ttatctttat cttaagaact ggatcgatgc cgtccaatgg catttggagg
     5581 acattatccg gaatccggag atcgacccgg tggaagcgct ggctatcaaa cgccgcatcg
     5641 acaagtcgaa tcaagatcgt acggatttgg tagagttgat cgatagtttc tttctggata
     5701 aatacaagaa cgtgaaagta ttgccggacg ctacgatcaa tacggaaagc ccggcttggg
     5761 cgatcgatcg tctgtcgatc cttacgctta agatctatca tatgcgtgag gaggcaaacc
     5821 gtccggatgc tactgccgag cataaggctc gttgtgagca gaagttggcc gtcttgttgg
     5881 aacagaagaa ggatttgtcg atggctttgg atcaattgct atccgatatc cgtgacggta
     5941 agaaatacat gaagatctac aagcaaatga agatgtacaa cgacccggcc ttgaatcctg
     6001 tgttgtacgg taagaaataa tggcaaatat attagtaata cgactttcgg ctatcgggga
     6061 tgtggcgatg accgttcccg ttatctattc cgcagccaag gcgaatccta cggactcgtt
     6121 taccgtgttg acgcaagcgt tcttgatccc ggtttttatc aaccgcccga agaacgtgaa
     6181 cgtgatcggt atcaatacga agagcacgga gaaaacgttg gcgggattgc ttcgttttgc
     6241 ctctgccttg gtgaaatacg atttcgatat ggtgctggat ttgcacgatg tgttgcgaac
     6301 catgattatc cgtacgctgt tccgcttgaa cggcagacgg gtgtttgttg tggataaggc
     6361 ccggaaagat cgtgcccggt tgaccgacgc gaagcataaa cgatttaaac aacttcgccc
     6421 ggtgatcgaa cgttatgcgg atgtgttccg caacgccggg cttaactata cggaatcgtt
     6481 cacctcgctt tatgagacct ctatcccgga tgtatccgcc ttggaacccc ttgtgggagc
     6541 gaagacgggc aaatggatcg gtatcgcccc cttcgccaag caccggggaa agatttatcc
     6601 gaccggggag atggagctgg tcatggccga gctttccgat cgagaggatt ttaccatctt
     6661 cctgttcggt ggtcgtggct acgaggaggc gctcttggat caatgggctt ttgagtatcc
     6721 ccgggtaaaa agcgtggcgg gcaagtattc cttggatcag gaactggcct tgatcagccg
     6781 gttggatctg ttgatttgca tggattccgc caatatgcat ttcgcttcct tggtcggtac
     6841 acgggtgctt tccgtttggg gcgctaccca tccctatgcc ggattttacg gatatcatca
     6901 ggatccggaa gattgtatcc agttggactt accttgccgt ccttgttccg tattcggcca
     6961 aaagccctgc ctgcggaagg attgggcgtg tatgaaacag ctcaatccgg atctaatcat
     7021 aaacaaggta ttaacctctt taaatgaaat ggtttcggat gaaggagatc attaacccgg
     7081 cgtacgggcg attcgaggat tttgtaaggc gtgtacctcg tatattttca gaagagggaa
     7141 aaacgattta taaggcgagg aatgagatca aggtttttga ggtagatggt gtggaactga
     7201 atgtcaagcg atatagagtc cccctcttga taaaccgtgt tatttatcgt tttttccgtc
     7261 agcctaaggc tgtgcgagcc tatgagtacg ctctgcgatt ggttgccaag gggtttgaga
     7321 ctcctgcccc gatcgcttat gtcctttttc gggagaaagg ccttttggga tatagttatt
     7381 ttatcagttt gcaatccagc tataagacat tgtataaagt cggacagcgt ccggtagagg
     7441 agaacgagga tatttttcgt gcgttaggca cttatatggc agagttgcat gaggcggagg
     7501 tctatcatgc cgatttctct cccggaaatg tattgtacga tcgtacggag gaaggggtta
     7561 ggttttcctt gatcgatata aaccggatgt atttcgggcc tgtctcgcta aaacgaggat
     7621 gcgcgaattt ctcccgcttg tggggacggg aagccgcttt tcatttaatg gctgagacct
     7681 atgccgagag ccggcatttt gataaagcgg aatgccttcg ttggatatta tactatcgaa
     7741 atcgtttctg gaagaaatat gcgttgaagc atgagattga atttgaatta tagactttta
     7801 tgaaaataca aatactccgg ttctgtttag ttgttagttg tcttttggcc tatgtatctc
     7861 cggttaaggc gttagaatgg tgggaaaagg tagagtatct gacttactcg ccccgttatt
     7921 tcgggccaaa tgcctttccg attcccgagt tggtgggagg aagcctgtcc agccgttggg
     7981 aagtggagct tcggggggaa tatcataaga cgcgaggcga tcagacaaaa gatatcttta
     8041 cccgtttgta cattcctgtc gtaaaggggc gtgtaggagt gaatgtcagt tgggtattcc
     8101 aagaatggta tgagatgtcg ccggaagtgc gggatgagcg ttatgcggta gaactgaaat
     8161 ccccgattgt ttgccggggc gacgtgatct ttaattttta tttccaagct ctccggagcg
     8221 agaagtggat ggatatcgtg gtaagcgcca acctgaaaac cgccagtggc ggacgcttgt
     8281 gcgacgctcg ttatacggat gcggcctctt attggttcga cgccaatctg ggacgtacgt
     8341 tgtggaagcg gaaagatgta aacgcttcga tccgtgtaca agctttagcg ggtttttatt
     8401 gttggatgac gaacgatgtc gttaatcgtc agaacgacgc tttctgttat ggggcaggtg
     8461 tgttaggaac ctatcggggg gtctcgttgg attgtaatta tgccggtttc cggggatatc
     8521 gggataatgg ggataagccg atgattctac ggacaaagct aaattatgag cttaagaaaa
     8581 atatcctgtc cttccaatat aaacatggaa tgaaggacca tctttatgat agctattcat
     8641 tagcttatat ccgttgtttc tgaatctgta aataatctat gctttcttga tcgacctgaa
     8701 taacgtggcg aagccgtctg tataagcctt tacgctgaaa tcttggatga tatgctcacg
     8761 tgaggccttg gcgaacgctt ccaatcgctc cgggttatcg ataagcgagc ggatagacgc
     8821 cgccatttgt tgaggagaag aaggcggcac taacaatccg gtgactccgt ctatgattaa
     8881 gtctcttgct cccggtatgt ctgttacgat acaaggtact gaacaagcca tagcctctcg
     8941 cacgactctt ggggaggcat cccggtgcga gggaagtata aacaactggg acgtgaccag
     9001 aaaagagatg gcgtcggaac gctgtcccag aaaatgaatt tgtgcgctta ccttcgactg
     9061 ttgggctaat tggaaatcat tttccccata ttctcccacg attgtaagat gtacccgtgg
     9121 atcatccaat aagataaacg catcaatcaa atcggttaag cctttgaacg gcctgttctt
     9181 cgtcgctccg atatagatgc aacgaaaggc gtcgtccgga atatcgtctg cttgtttggg
     9241 cgtacggact gcctccttga tccaatcgat atcaaatggc tttgtgctgg tcgttagtct
     9301 ttttcgtgcg atgaatcggg agagatattc ctcgatatct ttggtctcgc atacgacatg
     9361 ctccacggcg ggatttaata tgcctagata ataggtcgga tcgaaccgct tcaatttagc
     9421 ctgcgtacct cggtatgcga tattcttcgc ccgtgtgcct atggaggcga atagagcgtt
     9481 tgataaaccg gaactactcg gtgagtagat aaggtcgatc cgataagtct tgatgatttt
     9541 gcgcagggca cgaataacgt tccagttgaa cttcgaggta atgaccggca gatccaaagg
     9601 tgtacaattc ccatagatct ttttgtcggt atacgattgg ggagaagcga tatagatgtt
     9661 gaagtcctca agcttggaca atccttccag cattttgtag gtcgctatat cggcttcttt
     9721 atagactaaa agtatattca ttgtgtatgg ataaaatgga tttgctaaga ttgtgagata
     9781 ttctcgtata ctcgcatgaa atgagccgct aatacgtcgg gcatgaatcg ccgtatattc
     9841 tctcgtccgc cggaacgcat ggattcggcc agcttcggct cgttcaatac ggactctatc
     9901 aagctgcgca gctcttgctc atttctcgga tcggtatata gagcggacga tccgcccgcc
     9961 tcttccagac aagaaccggt agccgctatc actggaatac cggcaagctg ggcttctaag
    10021 atcgggatac cgaatccttc gaaaaacgag ggatagacaa ataaggtcgc catctgatag
    10081 aaagcggcta attcgttaaa aggtatatga gtcaagatac ggacacgacc ggacaggttg
    10141 ttttcccgga tataggtctc taccgtgtcc gtataaggcg tatgcttacc gatagcgatc
    10201 acggagatat cttctttcag ctctttcagg gcttttacca gaagcaataa attcttccgt
    10261 tcctcgatgc tccctacata taatatataa ggcccgttta tctgatattt ctcgcgtacg
    10321 gacgatttca cgtcttcttg aaccgcttgg ccgaatatcg ggtcacaacc ttggtaaaca
    10381 acctcgatct tgctttccgg aatgtggaag aagtcccgga tgtctcgcat cgtctgcctg
    10441 ctgatcgcta tgatcttgtc cgaccgtaaa caagcttgct tgaatttgta ggtatagatg
    10501 gaacgatcga tcggtttata gagctgcggg taacgcaaga agatcaagtc atgtatcgtt
    10561 acgaccgccg ggattccgtt ctgttttagg ttcatcggaa tctcgttgct caagccatgg
    10621 aacagatcga cgcgctcttt tcgaagcgta gccgtcaggc ccgaggtacg ccataaagag
    10681 ggaaatagct tatcgaacct gccctccgga taatggaatg atacattcgg acgctcctcg
    10741 atccgtttcc gcaacgcctc tttgcctttg cccggcgtat agagttgata ggtatgctcc
    10801 gggaaagaag cggacaggct attcacgacg aaccggctat aattacccag tccggtagcg
    10861 ttatgcgtaa tccgttttgc gtcgaaagcg atcttcatag gcttgaattc gatatatggg
    10921 gcaaatatac gatataattt taattacctt tacctcattt ccttccgaaa tccgccggga
    10981 tctctcccca tacggaggtt tcccatttga ggatccgggt ggtataggta tgggtgttca
    11041 accatttctc ggcccgctcg atgaggtcga agatcggctc gttgatcggt ttacgttcca
    11101 ataaggtttt gcatttcttt ttcttgaccc agctgatggc gttgcggcta tccgaataga
    11161 tcggcaggtc gcttcccttt tgctgtagca aggcgaggcc gtgcactaag gcgaggaatt
    11221 ccccgacatt gttcgtgccc tccttcagcg ggccgatatg gaagatctct tgcccggtag
    11281 cggtataaac gcccctgtac tccatatccc cgggattacc gctacaggcg gcgtctacgg
    11341 caagactctc gttgatcggg ttcccgatcg gggcttccgg cgcgagacgg gccacggctt
    11401 tcggggaaga ggcggtcttt aggtaatggg tatagccggc ctcgaaggct ttggcggctt
    11461 cctcccggtt ctcgaaggat ttatatttgg ctccctcttg cccgtctacc tgtgccttgc
    11521 attccgccca gttatcatag attcccgggt tcaacccttt ccatacgaca taaaacttat
    11581 tcttggccat ggctcttgct caagatttct tgtgagaatt gcgtataggt accgaacggc
    11641 gctcttttgt ccttgaagaa acggatcaag gcatccagcc ttctttccat gccgcaaccg
    11701 gaatggttgg tcatgataaa cggtaacttt agctctttcc gatcacttaa ggaggtgaac
    11761 tcccacggat ggaaataggt caggaaataa ccgtcctctt tccacgtcca aagcgccagc
    11821 ttacggtaca aggaggccgg aaggttatgg taagccagcc aaaacaaggg gaaacggacg
    11881 atcggggtca ccgaggcggg cagttgcaat acgccatctt tcatgaaata ggtacggggc
    11941 tgccccagat ggttgtaacg gccgggaatg caagtcgggt tcaaggacga gttgtataga
    12001 taaccggcct tatggatctc ttcttcttcg acgggcatca tgcgggccat acggaaaccg
    12061 ttcaccggtt gtccggtcag ttcctccaat gcctctttgg acttgcgtag atcggcggtc
    12121 tcgaacgacg agtgataaaa accatgcgaa gcgatctcat gtccaccctt ttggatgtcc
    12181 aagatcaaat ccttcgcatg aagggcgaag ttcgccgtgc aaaagaaagt cgcttttacc
    12241 cggtgacggg ccagacatgc caatatcttc cgggttcctt ccacggaagt acgcatttgt
    12301 tcctcgaacg gcaattccac gccgtgttcc aatggagcgt caaactcctc gatatcaaaa
    12361 ctaagtaata tcatgaatgt taattaatct ctatgaaata agatggataa gaagttcaac
    12421 gcttcccgcc gcaggacctt gaatcccata tcggataccg ctagtccttc tttgatgttc
    12481 gcattgatcg tccgtaagtt tatctctttc cggcgacttg ccttatagat aaattctgta
    12541 tcgaacagga agctattgat acgggtggtc aggaatatcg cttgtcccgc ttgactgaat
    12601 cctttcatac ctccttgcgt atccttgatc ttgatcctca aaatccatgt gttacatata
    12661 tgggatagct tggatagcac ttttcggaaa ggaggcaaat tctcctgata acttttgcta
    12721 cgggtagcca cgaccacgtc cgctcctcct agcaacgtct cgaccatcct gccgaacgag
    12781 tcgtttgtat aagggaaatc gtagtccgta taaataatgt agggagaggt acatcgcttt
    12841 actgcctctc gcaaggcata tccttttccc ctgttgggct tatagtctac gacgcagaca
    12901 ttcggtatca attgccggag gcggtcaatc gtttccggct cgtatccccg tctcgaacca
    12961 tcactgacaa taaaaaggtg gaaacgtacc gggctgaata atcgctccac ttcgtggaaa
    13021 tgggtggcta ctcgttcctc ccagtccgaa ggcgggttgt aacaaggtaa taccaaatct
    13081 atgtctgctc gtgcgttcat tccatttata cctttaccgg attataactc ctcgtacaca
    13141 tctcaaatgt cagctttagc cagatcagca tacaaggcaa cgcttttaac gcatacgggt
    13201 atacataatg cactcgtatg tatttcggga aaagatcgga cggagacatg ctggtcaata
    13261 taaaggcgaa gaccatcaag acaatatcca atgtcgaacg tttccacggt acagccgtat
    13321 accaaatagc gactccgata aacgctatga tataggtact ggactcgcta cccgtgctga
    13381 acagtacgac aaacatcaac accgaggcca ataacgtttt ccggaaagcc tcatatttat
    13441 attgactgat gcgtagataa ggcaggccga atactattaa tccccctatt atcagataaa
    13501 tgtccgagta actgaccgat cccgatatct tacgaaccat tcccaagaag gaaatgttct
    13561 gcatgagcgc gaataagttc tccgaatttt ttccggataa gtcctcgaac caaccggtat
    13621 attgggacat tatataatcc ggcccggaca atatcatcgg ggctacgacc atgacgaccg
    13681 cccatcctac gcaagatagg ctgaacttca tcttatggcg agagaaaaag aagaacgcca
    13741 atcccgtgat cccatacaat ttagtaaagg tacccaacat gatcacgaaa gtggcccata
    13801 cgtctttctc tttctctatc aatgcgtagg cgaggacaat gatagcggcg atactgatat
    13861 taaattgcga catgaaaagc gaggtaagca actcgtgggc acagaaccaa tagataaaga
    13921 tacgttcccg cttgatcccc ggtagcatct tgaccgccca gaataagaaa aggctttgcg
    13981 ccactgacca agtaagcagt cctaaccata acggtgtaat ggcgaacgga gccactacca
    14041 agctaaatac cggcccgtag tgaaaaatat cgttgtattc ttccggatag gcggcataga
    14101 gcggtaactc attcaacgta tgccaaaagg attgcctgaa gatggagaag ttgttatatt
    14161 tcccggggaa atacttggta atccatgcga taacccccag caatgcccat agccccatta
    14221 aggtactata tttgctgaaa aatggcttat ggatgattgt attgaactta tctataaatt
    14281 tcatcatcga atctacatct gtctacgggg caaaattaca taaaaacggt gacttttatg
    14341 cgagttaaat aaaaatacta tttttgcgtc caaaactggt aagagattat ttatgaatga
    14401 aatgttgaga tacacgatca ttcgtgtcat tctgtttgta atgggaggct ttcttgttct
    14461 cggatgttcg gatgaagatg atgtgggtaa tagtggagga acgagtaaat atggtttgat
    14521 acggatggcg gaggaggatt atgattcgtc gaatacttct tacatccttc aggatgagga
    14581 accggacgag gttcttttcg attcgtcaaa gcgaaaattc aaggtgaatg agcctttgca
    14641 ggtgtcagtt accgggcaga aggagttgat gcttcgtttc tattctccta gagctatcca
    14701 taatgtgatt gtctgggcta cggttgaggg ttatgaggat gaggtacggt ttgcggagtt
    14761 tactacggtt ttaccttttc aggagtttaa aatgaagttg ccttttctag aacgggcgaa
    14821 ggtttattat acacgttccg gcgaggaggt taccatagat gcccatccgg atatcgtggc
    14881 cgagaatata agtttgcggg ttgaatgtgg agatccggtc tatcaaggaa tgataaacgt
    14941 gaaacctaag tgggatattt ggtttggtaa atattccggt tcgaactggg gcaactttag
    15001 gccacatctg gctcgtgagg cggttgccct ttccttgaat atggccgcga tgttttcttc
    15061 ctcgcttttt gatgaggaac tggagaagtg gcgtggcaag ctgataaata acgagcaaat
    15121 cgtggatata gatgtgttga agaaacagat cacgaatcat ggcgggttgt gttatggacg
    15181 cgtggtgaat gttgtcggtc tgggtggagg aaataccttt gggctaggtg aatatgtcta
    15241 tctgacccat tatgccgacg atgccaatgg ttctgacacg ccgtatcatg agctggcaca
    15301 ctgcttgggg tatgggcata gtgggaatat gacgtactat ccggcggaag gcggtttccc
    15361 tacaatttgt atgaaggttt actcacagct ttccgtgagc aagaaattac cggtttattc
    15421 ccgccgtttc ttgcataccc ggaggaataa gaatctggta gagaataaaa acgtgtatac
    15481 ttcctcgaaa tacattatcg atgatccgga attggatgcc atagatggcg ggcttgggct
    15541 tgctccgatg gagacggata gggctggtga tgagggttct cctctctcat ttacactttc
    15601 tgtcttggat attcccggtg ccactgtgga aacttttcat ccgaaagcgg tccatcttta
    15661 tgggaatacg ctatatgtag caaatgacgc tccgggacat tatagtttgg aggtctttga
    15721 tgtatcttcc ggtaatgtgc gtcatgtgaa aagtatggtt gagtggatga acggagataa
    15781 gaaagagacc tttgcggggg agccaaacgg cgtgactcgc tcgtatggga aaatatatgt
    15841 cacgaatacg ggaagccgta cggatgtgtt tgatgcggaa acgtatgagt tcattacttg
    15901 tatcggtacg ggtacttggg gtgagggtgg ttatcagacc gttcatgcgt ttgatgtgac
    15961 ggctagtcaa ggggctgtct ttatccggga taaacggaaa ctggtagttg tcttggagca
    16021 agatgtacag cccggttccg ctgctcgggt acctatatat agccgtagcg taaatttaca
    16081 agaggcaatg ggtacttatg cagtagcggc acgaaatgat ggctttttat atgtgacggc
    16141 ccagaataaa aatataatct atttattcga tcctgcggac attcgggcag gggacacggg
    16201 ctttgcgccg tatctggtga cattgggatt tgaaaagtct ccccagtcga tagcgtttgt
    16261 aggggatcgt ttgtttgtta cgcttcgtgt cgatgataaa cggtcggagc tatgggagat
    16321 cagccctaag aacggaaaat tattgcagga ctttacagat tcgatggtct atcccgagaa
    16381 aatagccggt gctcgtcata ctttattggt agtggatcgt gcgacccaga cagtaaaagc
    16441 cattggccta tgattttttt attgattctt aggaataaag aagatggagt tcccggaaaa
    16501 agtttacatt tgcgaaaact attataataa cgtatgaaac gtgttttttt ggtcggatat
    16561 atgggagcgg gcaagacaac ggtgggaaaa gagcttgcca agctcgccgg tctttcgttc
    16621 atagatcttg attactatat cgaagggcgt tatcataagg ccgtttcgca gatattcgcc
    16681 gagagagggg aggaggcttt ccgagagata gaacggaata tgcttcacga ggtcgctgag
    16741 tttgaggacg tgctgatctc cacgggagga ggcgctcctt gctttttcga taacatggag
    16801 tttatgaacg cttctggcac gacggtttac ttgaaggtgt cagtcgagga gctggcgaag
    16861 cgtctggagt tgtgcaaaca tacccgtccg gtgttgaaag gacgttccgg ggaggaactg
    16921 agggcgttta tcgccgagag tctggagaaa aggaatccgt tttatacgaa ggcgtccata
    16981 acgtttgatg ccgagaagat gttaacagaa tctgatgtac atgacatatc gaacgcgtta
    17041 atgaaaatcc tatagcatat ggaagcgaac gacggccggc aggcacaggg ggcctatatc
    17101 ccgcaggaat tattgaaaga gatcagcaag gtgaataacc gtttgctcat cggtattcct
    17161 cgtgaacgat gcgaggcgga aaaacgtttg ccgttaactc cggaggcggt ggatatgctg
    17221 accgattgcg gtcaccgggt gctggtggaa agtggcgccg gattaggcat caactattcc
    17281 gataatcatt tctcggaggc gggggcggag atcgtcgata cgcccgcaga agttttccaa
    17341 gcggatctga tcttgaagat attgcctccg ttaccggtgg aaatcgcgtt tatgagacct
    17401 cgcacgaccg ttttctcatt ggtgcagttt aatttattcg ctcaagaggc tttcgagttg
    17461 atgatggcga aacggattac cgctatctct tatgagttga tggcggatga atataatcgt
    17521 ttcccggtgc tgaatgtcac ttccgagatc gagggggcgg cttccataac gatcgcttcc
    17581 gagctgttga gcaataccca aggaggtaaa gggatcttat taggcggtat cccgggcgta
    17641 tcccctacgg aagtggtgat tatcggggcc ggaaacgccg ggaccgtggc cgcgcgtgcc
    17701 gcgttggcct tgggagcatc cgtgaaagta ttcgatgatg atatcaataa attgcgtata
    17761 atacaacagg tcttagggca agggcttttt acttccacgt tccatccgaa tgtgctgcat
    17821 aacgcgtttc gtagcgctga cgtggtgatc ggggcgatgc gttatattaa tacgagacat
    17881 cgctatatta tcgctacgga cttggtgcgt acgatgaaaa agggagcttt ggtgatcgat
    17941 ctgagggtaa gccaaggcgg ttgctttgag acgacttgct gcttgtcgag ggaagatccc
    18001 gcggtgttcg agcaatatgg ggtattacat tattgtaaac tgaatatcag caaccgggtg
    18061 gctcgtacta cctcgatggc ttatagtaat atattcgtac ctttattatt gtcgttgggc
    18121 gacgccggtt ccgtgcaagg aatgatcaaa tcggataagg gctttagggc gggagtatat
    18181 atgtattatg ggaagacagt gaatagttat gtgtctaacc attttaatct atcatctaat
    18241 aatcttgatc tatacctctc tgctttttga tgcggaaaag ttttgaactc gcaaagttta
    18301 tgctttactt tgcggacgat ctaaatacca ataagcgata aagctaataa agtatattat
    18361 ggcagaacag acaaaagtta agacgctgga gaaggttgta attcgtttct cgggagactc
    18421 gggagatggt atgcagttaa ccggtacaat cttttcaaac ctgtccgcgg ttttcgggaa
    18481 cgagatttct acattcccag actatccggc agaagtacgt gctccacaag gaacactaag
    18541 tggtgtatct ggattccaag tgcacttggg atcgcgcaag atcttcacac ccggtgataa
    18601 ggccgacgta ttggtggcca tgaatcccgc cgcgctgaag gtgaacgtaa aacacctaaa
    18661 acccaatgcg attgttttaa tcgacacgga ctctttcaag aaaagtgatt tggataaggc
    18721 cttgtttacg accgatgatc cgtttactga gctgggattg actggcgtgc aggttgttgc
    18781 cgctccgatc tctacgatgg taaaagacgg attggttgag tttggtttgg acaataaatc
    18841 ggctcttcgc tgtaagaata tgttcgcctt aggacttgtt tgctggttgt tcgagcgtcc
    18901 actggaggag gctatgcaca tgttgcagaa taagttcgct aagaaaccgg ttatcgccca
    18961 agctaatatc aaggctttga cggacggtta taattatggt aataacatcc atgcctcagt
    19021 ttctacgtat cgtatcgaga gtaagaaagc cgagcctgga ttctatacgg acgtgaatgg
    19081 taataaggct acttcctatg gtttgatagc cgctgccgag aaggctggtt tgcagttgtt
    19141 cttgggtagt tacccgatca ctccggctac tgatatttta catgaattat ctaaacgtaa
    19201 ggatttaggc gttatcacgg ttcaggccga ggatgagatc gccggtatct gtacttctat
    19261 cggagctagt ttcgccggtt gcttggcggc tacatctact tccggaccgg ggcttgcctt
    19321 gaagagcgag gcgatcggtt tggctgtaat cgccgagttg cctttggtga ttatcgatgt
    19381 tcagcgtggc ggtccttcta cgggcttgcc gacgaagagc gagcaaacgg acttgatgca
    19441 ggctctgtat ggccgtaatg gtgagagccc tgccgtggta atagcggcct ctacgccgac
    19501 tgattgtttt gatgccgcat tttgggcggg taagttggcc gtggagcata tgactccggt
    19561 tatcttgttg accgatgcct ttatcgctaa cggttcttcc gcttggagaa ttccggaaat
    19621 ggataaatat ccggagatta agccgaatta cgtagctaat tatcaagacg agaaagtctg
    19681 gaaggcgtat cgtcgtaaca aggaaagctt ggttcgttac tgggcgattc cgggaacgga
    19741 aggtttcgct catcgtctgg gcggtctgga gaaagactac gagacgagtg cgatctctac
    19801 cgatccggct aaccaccaga agatggtgac gacccgtcag gctaagatcg ataagatcgc
    19861 cgactatatc cccgaactgg aagtgatcgg agatgaggac gctgatttat tgatcgttgg
    19921 ttggggtgga acctacggac acctttacga gacgatggag acgatgcaag agaatggcaa
    19981 gaaggtggct ttcgctcact tcaagtttat caacccgctg cctaagaata cggctgaggt
    20041 tctttctaag tataagaaag tggtggtggc tgagcaaaat aacggccagt tcgctaacta
    20101 tttacgtgga aaggtacccg gatttaaccc gtatcgcttc aatcgtgtaa agggacaacc
    20161 ttttgtcgtt gcgagattag ttgaggaatt cactaaaata ttggaggctt aaaagatgac
    20221 aacagaagaa actaaatttc aaccgaaaga ttataaaagc gaccagtacg tacgttggtg
    20281 cccgggttgt ggcgaccatg cggtactgaa ttgcctgcat aaggctatgg ccgaggtagg
    20341 agtggctcct cacaatatgg cagttatctc aggtatcggc tgttcttccc gcttacctta
    20401 ttatatgaat acgtatggct tccatacgat ccatggtcgt ggagcggcta tcgctaccgg
    20461 cgtaaagacg gctcgcccgg acttgagcgt atggttgatt acgggtgatg gcgactgctt
    20521 ggctatcggc ggtaatcatt ttatccacgc tgtccgtcgt aatatcgatt tgaatatcgt
    20581 tcttttcaac aataagatct atggtttgac gaagggacag tactccccga catccgaccg
    20641 tggtttcgta tccaagagct ctccttatgg gacggtggaa gatccgttta tcccggccga
    20701 gttggcgttg ggtgcccgtg gtaatttctt cgcccgtacg attgacgtgg atttgaagaa
    20761 tacgaccgag gtattgacgg cttccgcccg tcataaaggc gcttccgtta cggaggtatt
    20821 agtgaattgt gtgatcttta atgacggtat ccataaaggt atcgtagaca aggaataccg
    20881 tgcggatcgt acgattttcc ttcgccatgg cgagaaaatg gtttatggcg ctaacatgga
    20941 taaaggtctt gtgctagatg gcctaaaact gaaatccgta acgatcggac aagatggtta
    21001 tacgatggat gacgtattgg tacacgacgc ccatgagaag gataacacct tgcatatgat
    21061 gcttgccatg atgagcggtg atatgccaat tgcgttaggc gtaatacgag atgtggaggg
    21121 accgacctat gatgaggctg tccaccagca aatcgaggag gtacaagcga agaatcctac
    21181 acgtaaatta cacgaccttt tgatgaaagg tgagatttgg gaggtaaagt aatatatttc
    21241 tgattggata taagagaagg cgcaagatat ttatcctgcg cctttcttat atttatacgc
    21301 tggatttgtt tgtgcggaaa aaagtatata tctttgtttc agtcacaata aaagcgaata
    21361 cctatgatga caacttcgga aatagttgag atgctagcta aaagtatatg atttgtaaac
    21421 tccatattac aaatagacta agggttttgt taattgcatg gaaaagagta attattactg
    21481 aaaaatttcc ttaataagct gtgtacgata aaaaaaaata ttacttttgt accgcggtta
    21541 acaaggtgga gtcgcagcaa gctccaaaag gtcggaaagc ctcaccgtat cgaactagag
    21601 tagagagaaa agttatataa agtcaatcat ttaaattaaa ttcaagatgg ctaatttaga
    21661 tttaagcaag tacggaattg ttgatgtgaa agaaatcgtt cacaatccgt cttatgatgt
    21721 tctgttcgca gaagaaacta aaccgagttt ggaaggcttc gagaaaggcc aagtaactga
    21781 gctaggtgct gtaaacgtga tgactggtat ttatacaggt cgttctccta aagataaatt
    21841 tttcgtaaag aatgaagcca gcgaagattc tgtatggtgg acttctgatg aatataagaa
    21901 tgataacaag ccttgttctg aggccgcttg ggcagacttg aaggctaaag ccgtaaaaga
    21961 attgtctggc aaacgtttgt tcgttgtcga cacattctgt ggcgctaacg aggctactcg
    22021 tttgaaagta cgtttcatca tggaggttgc ttggcaagct cacttcgtaa ctaatatgtt
    22081 catccgtccg acagctgagg aattggctaa ctacggcgaa cctgatttcg tttctttcaa
    22141 cgctgctaag gctaaagttg acaactacaa agaattaggc ttgaactctg agactgctac
    22201 tgttttcaac ttgaagacta aagagcaagt tatcttgaat acttggtacg gtggtgagat
    22261 gaagaagggt atcttctcta tcatgaacta cttgaacccg ttgcgtggta tcgcttctat
    22321 gcactgctcc gctaacacgg ataaagaggg caagagctca gctatcttct tcggtttgtc
    22381 tggtactggt aagactactt tgtctacgga cccgaaacgt ttgttgatcg gtgacgatga
    22441 gcacggatgg gataacgaag gtgtattcaa ctacgagggt ggttgctacg ctaaggttat
    22501 caacttggat aaagagagcg agccggatat ctacaacgct atcaaacgtg acgctcttct
    22561 tgagaacgta acagttgccg ctgatggtaa gatcgatttc gctgataagt cagttacaga
    22621 gaacactcgt gtttcttatc cgatctatca catcgagaac atcgttaagc cggtttctaa
    22681 aggcccgcac gcaaaacaag ttatcttctt gtctgctgac gcatttggtg tattgcctcc
    22741 agtatctatc ttgactccgg agcaaactca atactacttc ttgtctggat ttaccgctaa
    22801 attagcaggt acagagcgtg gtatcacgga accgactcct acattctccg cttgtttcgg
    22861 tgctgctttc ttgtcattgc acccgacaaa atacggcgaa gagttggtta agaagatgga
    22921 aatgactggc gctaaggctt acttggtgaa cacaggttgg aacggtagcg gcaaacgtat
    22981 ctctatcaaa gatacaagag gtatcatcga cgctatcctt gatggttcta tcaatgaggc
    23041 tccgacaaag aagatcccgt atttcgactt cgaggttccg actgcattac cgggcgtaga
    23101 tccgaagatc ttagatcctc gcgataccta tgctgatcct gctcaatggg atgagaaagc
    23161 gaaggatttg gctgctcgct tccagaagaa ctttgctaag ttcacgggca acgaagctgg
    23221 taaggcattg gttgctgctg gtcctcagtt ataattgctt aaaaaacctt gatcaaaaaa
    23281 ggtcaaggtt taaaaatatc tttataaaaa agcgtggaat tactaattct gcgctttttt
    23341 tatgataact acgttaattt tattataaat gtaaagtagt tttaaaaaat attcctacct
    23401 ttagaccgga ttatctgtta taagaagagc ttaaaaagga gtaatgataa aaaaactggc
    23461 acttattatt ggctttataa tttgtttgtc atcttgtggc aaggattatg tctatcggat
    23521 tgaaggggaa ctttctaatc tggaagatca aaccgtatat gctgtatttg agaaggataa
    23581 ttataaagtg gttgataccg tggcttgtac gaaacccggg cagttccaga tcgatcaaaa
    23641 tgaagcgggt ttccattgtg tgactatttt ctttgcagat aaagagcatt gggttacggc
    23701 ttatctggaa ccgggagaaa ccgtaaaaat cacgggcgac gctaactctc cattgctatt
    23761 gcaggtaaag gggggacgga caaatgataa gttgaccgct tttaagaaaa aaatcgctcc
    23821 tttattgacg gaattgacaa atttatcaaa ttctttaaat agcaaggatt tgaacgatac
    23881 gatcgaggag acggatatcg ccgctcgttt ggcgaatgtt aatatgcaat tgagcgagga
    23941 agcgatccgg tacgtgaaag agaacccgga tgaagaggca tccgttgtct tgattcaatc
    24001 ttttttctca gatcccgatg atactcgtaa aattgatgag ttgttggcgt tattgaatcc
    24061 aaggttgaaa gacttttatc tggtgaagga gctggagcaa tatagcgccc gtgcgaaacg
    24121 tacggctttg ggtgcggaag ccccagattt ctccgtaagg aatatttatg ggaatacggt
    24181 aagtttggat tctttcccgc agaaatattt attgctgacg tttaccgctc cttggtgtga
    24241 tatgtgccag acagaggatc tatatctgga taaggtagcg atgaaatatc cgaaagatca
    24301 gttggacatt cttttggtta gcttggacga taatccggat aatgtccggg atgtactgaa
    24361 gaaggatagt atagcgtgga acttggtaac agattcggcc ggacaagcgg ctatgttgat
    24421 agatctgtat aacgtaagcg tattgccacg ctgtttcttg atagatgagg atcataagat
    24481 cttgatgaaa acagagaatg gaatcgagat caagcaaaca ctggaaaact tgttcgaaga
    24541 ctgagcgatt gaaaacagga ggttccggtt ttaatttgta attagtaact caaaattctt
    24601 aactatgtta gtaaaatctt atgccgctgc cgtgcagggg atttccgcta cggtcgttac
    24661 cgtagaagtg aactgttcca aaggtatcca attcttttta gtcggtcttc cggacgtggc
    24721 cgttcgtgag agccatgaac gcattatctc ggctcttcaa gtatgtgatt ataaattccc
    24781 ccgcaatcgt atcgttatta atatggcccc cgcagatatc cgtaaggaag ggtcttctta
    24841 tgatctgcct ttggcgatcg gtattctggc ggcggcagag cagatagatt catccaactt
    24901 atccaaattc gtattgatgg gcgagctttc tatggatggg agcctccaac cgataaaagg
    24961 ggcattgcct atcgctatta aggctaggga agaaggcttt aagggcttta tcttacccaa
    25021 gcaaaacgct tgtgaggctg cggtggtgaa cgatctggaa gtgtatggag cttcgaatat
    25081 caaagaggtg ctggagttta tggaggggaa acctacattg cggcctacgg tcattgatac
    25141 ccgtaaggag ttttacgacc gccagcaatt gtttgattgc gatttctccg atgtccgggg
    25201 acaagagaac gtgaagcgtg cgatggaggt ggccgcagcc ggcggacata atctgatcat
    25261 ggtaggtcct cccggaagtg gcaagtccat gttggcgaaa cgtctcccta cgatcttgcc
    25321 tccctttacc ttgcatgagt ccttggaaac aactaaaatc cattccgtag ccggtaagat
    25381 aggaggtggc acctccttga tggtacaacg tccttttcgc tctccccatc atacgatctc
    25441 taatgtcgct atggtaggag gtggcacttt cccgcagccg ggagagatca gcttggctca
    25501 caatggtgtc ctttttttgg atgagttgcc ggaatttaac aggagtgtct tggaagtcat
    25561 gcggcagcca ttggaagatc gagtgatcaa tatctcccgt gcccgtttca cggtggaata
    25621 tccagctggc tttatgcttg tggcctccat gaatccttgt ccctgcggct actacaacca
    25681 tccggaccgt ccttgtctct gttctcccgg agccgtccag aaatatatga accgcatttc
    25741 cggcccatta ctcgatcgta tcgatatcca gatagagatt gtccctgtcc ctttcgagaa
    25801 gatttccgag caacagccct cagagcctag tatcgctatc cgtgagcggg tcataaaagc
    25861 ccgtgcgatc caggaaaggc gttttgccgc ttatgagggt atttattgta atgcccagat
    25921 gaactccaag ctactccatc agtacgccgt tcccgacgct tccggcctct ccatcctcaa
    25981 aaccgccatg caacgtctct gcctctccgc ccgtgcctat gaccgtatcc tgaaagtctc
    26041 ccgcacgata gccgacttgg ataattcgga acatatcgaa gtccggcatt tggcggaggc
    26101 gatacagtat aggagtttgg atagggagaa ttgggggatg tgagattgca cttagaatac
    26161 atctattaac cataatagtg cagttactaa gctgaaaaaa ctatctttat attagttgga
    26221 aattgcgcta tttatggctg ttgaagtgaa taactgacgg cttgtcgagt gaacaactga
    26281 tggctatacc tggtggtcag cttacggctt gggaagtgaa taactaatca cttgggaagc
    26341 cttttgtgaa tgatttaacg tgctgtatgc cagtcaagaa aagatatccg agcagaaggt
    26401 ctttaaaagt aagctagctt acttttttag ggttgtttag gaattgcggt attcttgcgg
    26461 actcatacct acatggcgtt taaaatactt tccgaagaag gacatattag tgaaattcag
    26521 tgtataggcg atatcgtgga tggtaaggtt cgtcgatttt agttgtgcct ttgcgtccat
    26581 gataaccatc gaggtgataa tctctataca agtttttccc gtactttgtt tgacgatcgt
    26641 acttaggtgt gcttgcgtga tgccaagccg cttggcatac catgcaacgg atcgttgcat
    26701 ggtatagttt tgcattacta gttgagtgaa attcttactg attagctctg ctttggagag
    26761 cattgacagg tcttccgtct ggtctttata catgctgctg atccccatca gcataccggt
    26821 aaacaaatgg ttggtaatcc cgcgatttat tttcgtggcg taaaactcgt atgttttgag
    26881 taataactca aaataatctt tcataagagg ctgggctttc tcttttagct tatacaccgg
    26941 attgtctttc acgatataat gcatgtctat gacagctttg ctggagttcg cttggctgag
    27001 gaaatcagat gagaatccca tgaaatagat ctgtaggtcc ccgtctgccc tatggatctg
    27061 caggattgat ccgggcatga tggtgatgaa gcttccgggt tctaccttga gttgcgtcaa
    27121 gttgatggat gcctcgatct ctcctcctag gcatagcacg aaaatccccg ctttcaatcg
    27181 gcatgggtaa ttcgcataca gattcagcag gcctatatct tcgatcgaaa gcttcccgat
    27241 cacccaatct tgaggcaggt ctattttggg aatgtcattt tccatgtttg tttaattatt
    27301 cacttatcgg gaacgtttga caaaaatagg catttttaaa gatttgccgt gtcttgtgga
    27361 aggaaaatta tacgagcgtc tgaaacttgc ggtattccgg aggcttttcg gagtcgcttg
    27421 ggtgtttggg ctggactggt atggtttctt gtcgaaggaa gtagttgcca ttagaattat
    27481 cttttctgtt tcgttttgat tgaatttgga tgtatattgt gacaggggta tttccttgac
    27541 ctatcaaaat agcgaaagaa tcaggaagat aagtggcctt ttatgttaaa aagtaacgtt
    27601 ttcggtacac gttagacggc gaatatgtat gcaataggca gcattgggca atgcctatac
    27661 tgccgttggg catcgtgagt agtcgtgaat aggggtgtaa gtagtcgtga ataggcattc
    27721 ttatactgtt ataaccctat tgtaagactg ttttttccct ctctcactcc ccataatatg
    27781 aattacgatg aattattttt gctagaacaa aatgtcgttt tttgatatat ggctatcatt
    27841 caaataattg ctgattttct cttatgaatt tggaagtaag tagtactttg ccccgaaata
    27901 atcgatactc aagaggttga gattacaaat tgccattttg tcaaatcctt ttttcttcca
    27961 tcgaagcgac tatcttgtaa tcttgctttc tctaggggcg gctcttgtct gagcgcattt
    28021 tgtttaggca cggtttctaa taaaaggaac aatgggttgt aaaaatagaa catggccact
    28081 ctttataaat ggctctgtat gtgtaggggt gaggtatgga atctaaaaaa aggaataggt
    28141 aataagacaa atagaccttg taggatcttt gtgaaatata ttcttttgca tccgaattgg
    28201 gatcgaatgg atctatacga attgaagtaa ttgaaaaaag catttatatg aggaaaaaga
    28261 attttacatc tatgggaatg gcctgcttac tgggctgttg tttgatgttg ggtagctgta
    28321 gctctgaagt ggataatttg gatattccga agggcaaagg tttcgtgaaa atagatctgg
    28381 caccggaggt cggttttcaa acaaaagccg tggatgagag tgagtataag gatgtgaaca
    28441 attatactgt gcaagtgttt aaatccgggc aagaggagaa tcttattatt aatgatttgt
    28501 ataagaattt ggaagagaaa tattctttga atgttggtaa ctatgtgttg aaagccttta
    28561 cgggtgaaga taaaccggtt tcttccgatg tgttgtattt ttctggcgaa gctgcttttg
    28621 aagtgaagga gggaaaggag gtgacagctc ctgtaatatg taagcccagc tcagctcgaa
    28681 ttaatgttgt gttcgatccg aagatggatg agtatttctc cgactattcc ttgaagattg
    28741 agacagaggc gcagaaaccc tcttcttttg tttgggcaaa ggcgacagtc ggtccgatgt
    28801 attttaaggt aggtaatcag gaaaaggtcc aggttacggt aagcttgact aagaaagaga
    28861 atgtaaaagc agaagggacg gttaagacct atacgttaag tccagcggat gctttgaaac
    28921 ttactttgaa accagtagtc aacaatggca atttaggaat ttcgattaca attgaggaga
    28981 ctacggttga tcatccggta gatatcgtta ttccggggga ttgggtataa atatatataa
    29041 cagtaataat aagagattag aatatgaaag cgatcaatat atggatgttg agcacggttt
    29101 tgttttccgg cttgatgtcg tgtgagatga aagaggagat tttcgggaaa gagatcccaa
    29161 aggaaactgg ctatttgaca cttgacgtga gcgcaggttc ctctgcttct ttagcaacga
    29221 aaggagcaac tgatcagaaa gaagattttc cgctcgtgat caaggcgatg gattttgatc
    29281 ttactaaaaa ctatgagtcg tttgctaagt ttaaagaaga aaatgcgaat ggtgtgattg
    29341 agttgccgaa aggaaattat gagatagagg cgcattcgcc gggagagttt gccgaaaaga
    29401 tgtacgatcc ttattatgga ggtgtagaaa aagcagagat aatgcctagt gtggaaaaaa
    29461 ccgctacggt gaaatgtaag atccagaatg tcaaaattgc gatggatttt acctccgagt
    29521 ttataaacta ttatagcaaa tggtctatta cggtggatga caagtgcggt cattcagata
    29581 tttatacgca agaaaatcca aacccaactc cgatttattg gaaaatggct gctgagacag
    29641 ataagattta tgtgtcggga acagctatag tgaaggaaac gagtgaagaa gttattataa
    29701 atcagacatt aacgaagaag gaaagtgctg attttgtaga aagcgacagc ccctattttg
    29761 taggaggaga tggtttggcg atctcgttgg ctcccggaaa agaagtggat ctcaataaaa
    29821 ccggtatcac catcacggtt aacggtttta accaagagac aaatgagaat attgatatag
    29881 aagtggaagg tgatagtggc gaagagaatc ctgaacctcc gacaccaccg gtgacgggtg
    29941 atgatccgac aatcacgata ccgcaagctc tttatacgtt gcccgctgat gaacaaaaaa
    30001 atgcaaatgt tattatatca actcctgccg gcttgaaaaa tatcactgtc gcgataaagg
    30061 gaggaaatga gctttttgcg tcaatagtta aagatctatt tggtgaagag tttaaattga
    30121 taggaaatga agctttagga gagacgttga cgtcaatggg tgtaacttta cctgttggtg
    30181 gagaaaagag ctatgaattt ccggtacatg ccttttttag tttgttgcta gatccaagta
    30241 ctggtggagg tgttacaaca gatccagaag gacacgtatt taatattacg gtggaagata
    30301 atgatggtaa agtcgtaaaa gataaattaa gtgtaaaagt ggctgaataa tatgaagaca
    30361 atatatacac ttttattttt tgtgttggta ttaggtttgg tcgcttgcca ggccgaggat
    30421 gatacatcca tgaaaaatac cggttattta agtatggata taacgaccaa taattccaca
    30481 gccaccaaag cgggaagtga ggaggttgtt tataatccca aacagttggc ggtacaaatc
    30541 ttgaatgatc aaggaggtgt tgttaaggaa acggatgact atacggcgtg ggatggagag
    30601 cgattttcct tgcctacggg taaatacgtg gtgaaagcct cttcaaatgg cttcgatggt
    30661 aaagctgccg agtttgataa gccctattat gtgggatcag ctgaggtaga ggttatggca
    30721 ggaaaggatg tgacggccga agttatctgt acattggcga atgtcttggt gactgttgaa
    30781 tttgacgagc tgttcaagaa aagctttaag tctgcgacca ttgttgtggc tgattcggca
    30841 gaccaaactg gaacccgcct tacctttgag ttaggtaaga acgagacagc aaaggcctat
    30901 ttcccagttc ccgagaagtc gttgattatc tcaacgagcg taacgaatca aaagggtaca
    30961 ctacattcta agaaagatac cgttcgtgcg gtaaaagctc gagataatgt tcgcttgatg
    31021 tataaagtgg ctgactcgcc aaatggttct accagtattg atattacttt ggacggaaca
    31081 atcaagacct ataatttcac cataggtgtg cctctgaccg ctaagacaac tctatcggca
    31141 agtgcggcga acgcttggag ttcatttgct tacttggagg ggaaggtgct ttcaaaggca
    31201 ggtgtcttgg atcaaagcaa gttggcgatg gaatataaac tggcaacaga cgaggcttgg
    31261 actccggttg cgtatctgac cgtaggtgaa aacgatacct attcggtaag gattacgggc
    31321 ttgactcctg caacaaaata tcaataccgt tttatctata aggatacgga agaggtggca
    31381 agcgaaatcg tagagtttac tacggaggcg gctatcgcat tatataatgc taattttgat
    31441 ttatggtatc agaatggaaa gacatggtat gctggggaat ccggtaaatc attctgggat
    31501 acgagtaacc cgggtacgac aacggggttg ggagccatag tgaatatcaa tcctacccaa
    31561 ggtagttcag cggttgtgca tacatcgggc ggaaaatctg cggagttgaa atcccagttt
    31621 aaggtgaaat tcgcagcggc gagcctgtat accggatctt ttggtgggct ggttggtatg
    31681 aatggtgcta agatcaattt tggtcagccg ttcgcttctc gtccaacagc attaaagggc
    31741 tggttccaat acgctccggt aaatgtaact catgtagggg ataatcttcc ggctgacgca
    31801 gttgttgaaa aaggagatcc tgatgtttgt tctatttata tagcgatgtc taaaaagcaa
    31861 tatactatag ataataccaa aatggcagaa actgcgatcg attttgagaa tgatgcgaac
    31921 attatcgcct atggtgaggt gcctgtgtcg gaatgcgtaa gtaccaacgg acaatggaag
    31981 gagttcaata tcctcttgaa atataagaat ctgacggaga aaccgaccca tatcattgtg
    32041 gtctgctcgt ccagcaagta tggcgactat ttcactggag gcgatggcag cataatgtat
    32101 ctcgatgatt tttcactcat ttacgatgac gagcctacaa tgtggaaata aaccataggc
    32161 tgaaagtcta tgtagggaac aataagtttt tactataaat ctatttggca agtaaggata
    32221 tcttccttgc taagtagatt ttaaatatct ttgtggcaat ataaaggata gaactagaaa
    32281 atggcaataa caatagagcg aattatttga atgagtagaa aactatttac cttattgctg
    32341 ttattagcaa tagtgaccgg taccgtaaat gcacaacgcg gtaaacgcac catcaagcgc
    32401 atcgaccgag aggtacagga ggctgtgttc atcccgaaag gaacatggat ggccggaggt
    32461 gccgtatcgt attccgagca tgacgagagt aacttgaact ttcttgttat aaaggatttg
    32521 gaagggaatg gctataattt tgcgataagt ccgtacgtgg gctatttctt ccgggataat
    32581 atctcggccg gtgttcgctt cgcttaccgt aggaactatt tggatctagg gaatgtggat
    32641 gccaatttgg gcgacattac catctcgttc aaggacctct attatctgga gcataaatat
    32701 gagacatccg gtttcctgcg cacctatatc ccgataggga agagcaagat attcggtctc
    32761 ttcaacgagg ctcgtgtgac ctatggctac ggtacgggca agaattccac aggctcgggg
    32821 gctaattatg atggtactta ccagaaggta cagaacctac agattggttt cgcccccgga
    32881 ctggctgcct ttatcaccga ttggagcgcc gtggaggtgt cggtcggtgt gatgggtttc
    32941 gatttcaagt ggatcgatca gacaaccaac caagtggagc agggttcgag ccgtacatcg
    33001 tccggtaatt tcaagatcaa tcttttttcc attaacatag gtatgacttt ctatttgtaa
    33061 ttggatatgc gaataatcaa tgatatatat aaagtgacct gtcgcttttg cctttttgtt
    33121 ttcttcgtgc tggtttcctg tgcgatagag aatgatatac cctatccgat cgtcaatgcg
    33181 ggtatcacgg acattcgtgt ggagggacag cgtccggctg aaggctcttc ggatgatgcg
    33241 gcattaattg atgcttcggc aaagaccata ttactgtatg taaacgattc tgctgatatt
    33301 tctagattga aacttactcg tttggtggtg aatccaagga atgcgcaggt tttggttgat
    33361 tcgactctct gtgctaatcc taataaattc ccgtttgccg gattcgcctc attggatagt
    33421 attcctatgt catccaatac gagggtcgat tttaccaaac cggtcaattt tactataaaa
    33481 acctatcaag attatgtatg gcaagtaaag gtgaagcaaa tcatagaccg gaaggtcgag
    33541 gccaagggta tgatagacta ttctattgac gaactggata atcgagtgat tatttatgta
    33601 gggaaaggag agaatctgaa gaatatctct ataacctctt tggctttggg tggagcctat
    33661 ggcgaggtga cgccaaatcc tactaccgtg aaagatttca cctctccaca gaagtttttg
    33721 gttcagtatc cctggagcga gcccaataag gggacaatat ggacggtata tgtccgtctg
    33781 accgatgagg agggaggctc gcagccttca gccggagatc tttccgtgaa tacatggagc
    33841 aagtatgcgt ttgtggaggg gaaagcaacg gaggctaatt gttcgtttga gtatgtgaaa
    33901 cagggagaga cttcttggaa catggtttcc gcgaaggcaa acggttcgaa ggtttctgcg
    33961 aagatcgagg gattgcagcc cgccacggct tatcaatgcc gactggtgga tgcctcggga
    34021 agcgtgttgg gcgagtctac cttcacgaca gagactgcca caccattata taatggtaat
    34081 ttcgatctgt ggcatcaaga tgggaaaaca tggtatgccg gtgaggcggg tcattcattt
    34141 tgggatacga gcaatccggg tacgacaact ggattggggg ctgtggtcaa tatcaacccg
    34201 actcaaggaa attcaacggt tgtgcatacg ccgggtggaa aatctgccga gttgaaatcg
    34261 cagtttaagg tgaaatttgc cgctgcgagc ctgtataccg gatcttttgg cagtttggtt
    34321 ggaatgaatg gtgcgaagat caaattcgga aggtcgttcg cttcgcgccc gttcgcattg
    34381 catggctttt tccaatacgc tccggttgcg gtaactcata taggagataa tcagcctgcg
    34441 gggacgcttt caaaaggaga tatggatgtt tgctctatct atatcgcctt ggctaaaaag
    34501 caatatacgg tagataatac cgatactgat acctttattg atttcaaggg ggataataat
    34561 atcattgctt atggagaggt tcctgtaaag gaatgtgtat ctacgaatgg ggcatggaag
    34621 gagtttacca ttaatctaga gtataagacg caggaaaagc ccggcgatat gcaccttatc
    34681 atcgtggcaa gtgccagcaa gtatggcgat tattttaccg ggggagacgg tagtgtgtta
    34741 tatgtagatg atttcgaact tatatacgac taaataatat gatgaagcag attgataaat
    34801 tttgttgttg tatattctca ttatttctca tgatggcctg tcaggaggaa gaaataatgg
    34861 ataaaaccgc cggctttcag gtatccttgc aggatatggg tgttgccatt gagacgaaaa
    34921 gtacgccagc ggaattggga aagccactag cggatcagtt taagcttaag gtcgtgaaga
    34981 acggggattc ctctccgttg tttgatggta attataccag ccagacgata cctgcttcgg
    35041 ccggtactta tacgatatct gcttcctatg gagataatcc ggttttagcg ttggatgcgc
    35101 cctattattt aggcgacact actaatgtgg tgattaagga gggcgagcag aagaaaatta
    35161 ccttgagttg caaggtggcc aatgcgttgg cttctgcctc tttccccact gatacggagt
    35221 tgaagaaaat cttctcttct tattgggtga aagtagttgt tgggaagtcc tcttgtaaat
    35281 tgacttctga tagtaagaaa agtgcctatt ttcaagcaga gaaacaggtt gccttttatt
    35341 ttgagggaac aaaggtgagc ggtaaggatt tttccgagga gttaaaacat aaggatttgc
    35401 cttcggtatt gaaagccgga catcatgtta aactgacatt gaagttatcg gatgatttat
    35461 tgttggatgt cgctaaagtt gaaattaaaa aggagacaat aacgagcgat atcccgatgg
    35521 attggttgcc taagccgaaa gttgaggcgg aaggatttga gaataatata ctttcctttg
    35581 ctgagacaga gactaaaacg gcaatattga atttaaatac ggcttcagca ctgcaagact
    35641 tgaagctgaa atttactttt ggtgatccgc aattttcaag cttgaatgat aaggactatc
    35701 ttttatctgt tccggcagat aaagcggaaa tggaaaatgt gttaggcatt gtattgcctg
    35761 agattggtgt agataaagcc tctttagatt tgacttccat tgtcgctaag ttgcgaacag
    35821 atgcgggtac gacagtagaa aataagattg aagtagatgt gagagcgaat aatcgctgga
    35881 gtagtgagga gattaaaggg caagaaaacc caagccgggt ttatacgttg aggtgtaata
    35941 agccggaaat ggcagtatct gttcaacccg gaaatatctg gacgaaagag tttacgattg
    36001 atgaactgac cgttactaca ggagatccgg aggttatcaa gtctaagttg aaatatcagt
    36061 ataaagaaaa gtccggaggt gatgatactt ggaaagacat tcaagatatg aaagtgttat
    36121 tcaatgaaca tccccaaaat agatcatatc aagtgagagc ggtttatcgt gatgtggtta
    36181 tgacggatgc tattgatgtg gagctagaga atccggtgca gttgccgaat tctgggatgg
    36241 aggagtggca
//
LOCUS       DBMDTB010000029        35987 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_479_length_35987_cov_12.152706, whole genome shotgun sequence.
ACCESSION   DBMDTB010000029 DBMDTB010000000
VERSION     DBMDTB010000029.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 35987)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 35987)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35987
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_479_length_35987_cov_12.152706"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            174..1019
                     /locus_tag="ACZPB4_06685"
     CDS             174..1019
                     /locus_tag="ACZPB4_06685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BRO-N domain-containing protein"
                     /protein_id="HIR1097940.1"
                     /translation="MTQKESIRLFEERKVRAIWDDEQEEWYFSIVDVISILTDSPNPR
                     KYWSVLKTRLKREGSELTTNCSQLKMQAADGKKYLTDVANTEQLFRLIQSVPSPKAEP
                     FKLWIAQVAKERLDQMQDPELSIEQAMADYKRLGYSDNWINQRLKSIEIRKDLTDEWK
                     KRGLEEGLHFATLTDIIYKSWSDMTSKEYKRFKGLRKENLRDNMTNKELVLNMLAELS
                     TKEISEASEPDTFSEHINVAQQGGEVARNARLELEAKTGKSVISPLNAQKIISLKKGE
                     NERDV"
     gene            1093..2709
                     /locus_tag="ACZPB4_06690"
     CDS             1093..2709
                     /locus_tag="ACZPB4_06690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HIR1097941.1"
                     /translation="MITVNNLDVQFGKRILFQDVNMKFTPGNCYGIIGANGAGKSTFL
                     RVISKQLDPTRGSVNLGPGERLSVLSQDHFAFDEYTVMDTVLMGHTTLWEVMSEKNAL
                     YEKPDFSDADGIRVSELEEKFAEMEGWNAESDAANLLSGLGIKEDLHYMYMKDLSGKQ
                     KVRVLLARALFGQPDNLLLDEPTNDLDLETVSWLENYLSNFEHTVLVVSHDRHFLDSV
                     CTHTVDIDFGKLQLFAGNYSFWYESSQLALRQQQNQNKKAEEKKKELEEFIRRFSANV
                     AKSKQTTSRKKMLEKLNIEEIKPSSRRYPGILFTPNREPGNQILEVKGLSKSIDGQVL
                     FKDLNFFVEKDDKIVFISHDPRAMTALFQIINGEEKADAGTYQWGQTITTSYLPLDNS
                     KYFNTDINLLDWLCQFSPDTNEVFLKGFLGRMLFSGEELMKKVSVLSGGEKMRCMISR
                     MMLTDANCLILDTPTNHLDLESIQAFNNTLKTFKGNILFSSHDHEFIQTVSNRIIELT
                     PNGIIDKMMDYDDYITDPAIAELREKLYSK"
     gene            2706..4574
                     /locus_tag="ACZPB4_06695"
     CDS             2706..4574
                     /locus_tag="ACZPB4_06695"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070395 - lipoteichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HIR1097942.1"
                     /translation="MKKRLLFILIVFIAWLPVFVIQKPVFMFYQHALSEACTFTDFLQ
                     VMLHGLKLDCTIAGYLTAIPLLLTLVSVWLPGAWLKKVLKGYFLIMGILVSAIFSVDV
                     ALYSFWGFRLDATLFFYLQSPADAMASVPLGLFFIQLLVFVAYALGIYAWFTFILRFA
                     PVKPSFPPTGLEQLGSTFAILLAGGILFIPIRGGVTTSTANVGMVYFSQNQFLNHSAI
                     NPCFSLIASLSKQQDFASQFDFYPEEKRKALFDTLIQAQDSLCPGDSIPTEPVKLLTT
                     TRPNILIIIMESFTANAIEAVGGEPGITPNLNRLSKEGVLFTNLYANSFRTDRGLVSV
                     LNGYLAQPTTSIMKYPVKSQTLPSIAKSLNKEGYTADMLYGGDINFTNMQSYFYSSGY
                     SKITADRDFPLSSRLSKWGANDDITFSHLYEDIKQRPVDGKPWLSTFLTLSSHEPFEV
                     PFHHLEHPYLNSVAFTDSCIGNFIDTFKELPAWKNTVVIFVSDHGYRYPENMQEYGPL
                     RFHIPMLWLGGAIAEPKVIDTYANQTDLAATLLNQMGLPTDEFSFSKDILNPCVPHYA
                     FYTFNNGFGFIDESGVSVYDNEGNKILVEEPESGNETRLEKGKVLLQTLYDDLGNR"
     gene            complement(4638..6176)
                     /gene="rny"
                     /locus_tag="ACZPB4_06700"
     CDS             complement(4638..6176)
                     /gene="rny"
                     /locus_tag="ACZPB4_06700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HIR1097943.1"
                     /translation="MVGMYIIIPIVTFIIGGLLAWLGMRFLLKSKYDSVLQEAEKEAE
                     VIKKNKMLEVKEKFLHLKADLEKQVSQRNAKIQSVETKLKQRELTMNQRQEELQRRNN
                     EVEAVKENLSSQLELVEKKKQDLDKLHQKEVEHLEAISGLSAEEAKERLIESLKDEAK
                     TQAASYINEIVEEAKMTANKEAKKIVIQSIQRVATETAIENSITVFHIESDEIKGRII
                     GREGRNIRALEAATGIEIVVDDTPEAIVLSGFDPVRREIARLALHQLVQDGRIHPARI
                     EEVVTKVKKQVEDEVVETGKRTVIDLGVHGLHPELIRMIGKMKYRSSYGQNLLQHARE
                     TANLCAVMASELGLNPKKAKRAGLLHDIGKVPDDEPELPHAILGMKLCEKYKEKPDIC
                     NAVGAHHDEVEMQTLLAPIVQVCDAISGARPGARREIVEAYIKRLNDLEQLALSYPGV
                     VKTYAIQAGRELRVIVGADKIDDKDTENLSAEIAKKIQDEMTYPGQVKITVIRETRAV
                     SYAK"
     gene            complement(6284..6574)
                     /locus_tag="ACZPB4_06705"
     CDS             complement(6284..6574)
                     /locus_tag="ACZPB4_06705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000917 - division septum assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HIR1097944.1"
                     /translation="MDEEFLINIVIAGKKYPLTIKRHEEELARAAADQINSKILQYRQ
                     HFAVEVDTKDLLAMVAFQLSMHNLELEKRNDTNPFTDKIQELTTELEGYLKK"
     gene            complement(6580..6873)
                     /locus_tag="ACZPB4_06710"
     CDS             complement(6580..6873)
                     /locus_tag="ACZPB4_06710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097945.1"
                     /translation="MTEDHKRLLAVFEVRVRDLMALCDQQKRRIDELTAALSLKDEEL
                     RQAKDMIEGLNAKCDNMLTARIVSTNEEEMKNARMRLSKLVREVDKCIALLNE"
     gene            complement(7024..7224)
                     /locus_tag="ACZPB4_06715"
     CDS             complement(7024..7224)
                     /locus_tag="ACZPB4_06715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HIR1097946.1"
                     /translation="MIELIGTNAGLVWNVLNEGGKMSFKAVKKATKIKAEKDMYAAFG
                     WLAKEGKLAFEEIEGEMYVSLV"
     gene            complement(7347..8036)
                     /locus_tag="ACZPB4_06720"
     CDS             complement(7347..8036)
                     /locus_tag="ACZPB4_06720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="B3/B4 domain-containing protein"
                     /protein_id="HIR1097947.1"
                     /translation="MISITLSSEISEACPDLHVLAIACQVKNTEPDERLWEEITRVEE
                     DIRSTCKIEDINKWTPIFATRQAYKRLGKDPNRYRPSAEALRRRILRGLPLYKIDTLV
                     DIVNLVSIRSGYSIGGFDADKIVGGLELGVGKEGEIYHGIGRGELNIAGLPVYRDGVA
                     GVGTPTSDEERTKIEMSTTSLLMILNGYSGKEGLLEAGGYSVDLLKRYVSAVNVEAEL
                     ICRENRGKITL"
     gene            complement(8064..8891)
                     /gene="pgeF"
                     /locus_tag="ACZPB4_06725"
     CDS             complement(8064..8891)
                     /gene="pgeF"
                     /locus_tag="ACZPB4_06725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan editing factor PgeF"
                     /protein_id="HIR1097948.1"
                     /translation="MMKMKIQENKQIEVSRFSGLSGYRDISHFTTTRHGGVSTGTYAS
                     MNPGVYTEDDPGFIRKNLELLSDAVGISLENMVIPHQTHEDRVLAIDASFLSLNDKER
                     KQRLEGVDALVTNVPDVCIAVSTADCVPVLLYAPDRKVVAAVHAGWRGTVLHIARKAA
                     SLMIEAYDCDPTQLVAGIGPSISQAAFEVGEEVVKAFQMAGFPMERILRRNAETQKAH
                     IDLWETNRLQLLEAGLLSEHIEIAGICTYIRYEDYFSARRLGVKSGRILTGICLKKS"
     gene            complement(8863..10023)
                     /gene="obgE"
                     /locus_tag="ACZPB4_06730"
     CDS             complement(8863..10023)
                     /gene="obgE"
                     /locus_tag="ACZPB4_06730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HIR1097949.1"
                     /translation="MAESNFVDYVKIYCRSGKGGRGSSHFRREKYIPKGGPDGGDGGR
                     GGHVYLRGNRNYWTLLHLKYERHIMATNGESGSAKRSSGKDGEDRVIEVPCGTVVYDA
                     ETGEFICDVTEDGQQVMLLKGGRGGLGNFNFKTATNQAPRYSQPGEPALERTVILQLK
                     LLADVGLVGFPNAGKSTLLSVVSAAKPKIANYPFTTLEPNLGIVSYRDNRSFVMADIP
                     GIIEGASEGKGLGLRFLRHIERNSLLLFMVPAEADDIKKEYEILHNELVKYNPELLDK
                     RRVLAITKSDMLDEELIESLSQDLPEGIPYVFISSITGLGIVELKDLLWKELNKENFH
                     EAERIVHKNIDVSTLEFEDDDEYIFPVDEDEDDPDEEYEEYWDDDEDEDTRK"
     gene            complement(10039..10611)
                     /locus_tag="ACZPB4_06735"
     CDS             complement(10039..10611)
                     /locus_tag="ACZPB4_06735"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0019205 - nucleobase-containing compound
                     kinase activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HIR1097950.1"
                     /translation="MLNVVIFGAPGSGKGTQSELIIKEYGLDHISTGDVLRGEMKAET
                     ELGKIAKDYIEKGQLVPDELIVDMLANVLDSKKPAKGVIFDGFPRTIPQAKALKKMLN
                     ERGTDVSVMLNLQVEEEELIKRLLERGKVSGRSDDNLETIKSRLDVYHTQTAPLADYY
                     VGEGKHVAIKGMGTIEEIFGRIKEAVNNVK"
     gene            complement(10648..11184)
                     /locus_tag="ACZPB4_06740"
     CDS             complement(10648..11184)
                     /locus_tag="ACZPB4_06740"
                     /EC_number="2.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010183721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0043174 - nucleoside salvage [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyltransferase"
                     /protein_id="HIR1097951.1"
                     /translation="MDRIRLKDKEFELFIPESDIQAAIAKMAVQIKADVEGKNPLFVG
                     VLNGAFMFVAELMRELDVPYELTFARYSSYQGTSSTGILNEIMPVQADICGRMVILLE
                     DIIDTGFTMSYVMEKLRSEGAADVRLATMLFKPESLKCELTPDYVGLQIPADFIVGHG
                     LDYDELGRSYKDIYKVVE"
     gene            11308..12819
                     /locus_tag="ACZPB4_06745"
     CDS             11308..12819
                     /locus_tag="ACZPB4_06745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional ADP-dependent NAD(P)H-hydrate
                     dehydratase/NAD(P)H-hydrate epimerase"
                     /protein_id="HIR1097952.1"
                     /translation="MIKIFATDKVKELDQYTIQHEPISSIDLVERAATTFVHEFCRRY
                     SKQVRIVIFAGQGNNGADALAIARLLNEESYRVETYLFNPTEHLSVECEQNKQRLLDM
                     ERIEFTEVVRDFEPPTLTDRDVVIDGLFGSGLNRPLTGGFAAMVNYINQSEAEVVAID
                     IPSGLFGEDNRKNDSEAIIKASLTLTFGFPKLAFLFPENEQYVGEWKILDIGIHPDAI
                     YETASPYSLVTEEDISYSLKSRKRFAHKGTFGHALLIAGSKGKMGAALLSAKACLRSG
                     AGLLTVHIPTRGESIFQTAFPEAMLSLDANPDYFSTVPEIGSYSAVGMGPGLGQHLES
                     AAAIERILQSSTKPVVIDADAINIMASNKDLFNKIPPRSILTPHPKEFDRIAGESTNS
                     YDRLMKAQSFAAEHKICIVLKGAYTAICSPAGNIYFNSCGNPGMATAGSGDVLTGIIL
                     SLLAQDYSPETAAVVGVFLHGTAGDLAAAFRSEESMIASDITDMLGKAFKQIK"
     gene            13541..14782
                     /locus_tag="ACZPB4_06750"
                     /pseudo
     CDS             13541..14782
                     /locus_tag="ACZPB4_06750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010183724.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-disaccharide hydrolase"
     gene            14811..16325
                     /locus_tag="ACZPB4_06755"
     CDS             14811..16325
                     /locus_tag="ACZPB4_06755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HIR1097953.1"
                     /translation="MKNISRRSFLKTGAVAAAGLTIVPGSVLGKSFGYTAPSDKLNIA
                     GIGVGGMGRRNLANMNTENIVALCDVDWHYADKTFKDYPKAKRFKDWRVMFDEMGKSI
                     DAIMVATPDHTHAGVTAHAITLGKHCYTQKPLTHSVYESRLLTKLAKKYKVATQMGNQ
                     GNSFDWCRQIAEWIQSGVIGDVYEVHCWTDRPIWPQGLMKPNDTPKCPKTLDWDLWIG
                     PAQKRPYNPVYTPWNWRGWWDFGTGALGDMACHIMDPLYWALDLKYPTSVIGSSTLSN
                     LYSPPHAQIVTYTFPARPPKGNVKMPEVKVYWYDGGLMPPRPEELKDGQMMGDENGGI
                     IFIGTKGKIMTGCYGMNPTLLPVSDMEHFNQPKPTIPRVKGGNGDIWSTNAHEQDWIR
                     ACKESPENRTEASSNFQFSGPFNEMVVMGVLAVRLSGLQGLHRELQWDGENMRFTNIS
                     PNDKIKIVTVDDFKVIDGDPRFDRRFAEFNAAEMANEWIKHTYNNGFSLPDMPR"
     gene            16347..17201
                     /locus_tag="ACZPB4_06760"
     CDS             16347..17201
                     /locus_tag="ACZPB4_06760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HIR1097954.1"
                     /translation="MIRHIYKIMIAIVCCLLAIPSEAQTKAEKNGWRLGMQSYSFHLF
                     PLTEALDKTQELGLKYIEIYPGHKLGGKWGDKVFDFNLDAQTQKEIKELAASKGIKIV
                     GTGVYVAEKSSDWEKMFKFAKAMDLEFITCEPALSDWDLVEKLSKQYNIKISVHNHPQ
                     PSDYWKPENLLKAISGRSQSLGSCSDVGHWRREGLNQIDCLKQLKGRIISLHFKDIAP
                     KKAGENEQHDVIWGTGILDVKGMLKELKSQNFKGVFSIEYEYNWENSVPDIKECIQYF
                     NKTANEIL"
     gene            17300..17590
                     /locus_tag="ACZPB4_06765"
     CDS             17300..17590
                     /locus_tag="ACZPB4_06765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HIR1097955.1"
                     /translation="MASDNKIIELIKQGDIAAFNTLFKSVYLQLYIHCRKFIPAPEDA
                     KDILQNVFLRFWEKRENIDIHTSLNAYLYRAIQNECLNYLRSTGTPYLISHN"
     gene            complement(17708..18577)
                     /locus_tag="ACZPB4_06770"
     CDS             complement(17708..18577)
                     /locus_tag="ACZPB4_06770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecR family protein"
                     /protein_id="HIR1097956.1"
                     /translation="MKEYIKNIIAESLKDEVDVDREWERLFSSIEKKTISKMKTRRLF
                     LQYMKYAAAVVLGIGVSLSTLYLTNQENLSTVGNYKLVTSKGEKSYLQLPDGTRVWLN
                     SCTTLEYAENYGHSNRSIYLDGEAYFEVAKNKDLPFVVKANGIDVKAIGTAFNVSAYM
                     EDSQLTTTLFNGKVAVQPTLTKQEVLLEPNQVAVYDKSRNKIEVVPYDKKLFAQWRGG
                     FLSFKMMYLQDITKLLERNYNVVFRYENQGIKKLRFSGSFRNNEDLSEILNVIKTNTG
                     IRYQILKDTIVIK"
     gene            complement(18660..18917)
                     /locus_tag="ACZPB4_06775"
     CDS             complement(18660..18917)
                     /locus_tag="ACZPB4_06775"
                     /inference="COORDINATES: protein motif:HMM:TIGR02937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HIR1097957.1"
                     /translation="MDKQEAVEDNDPYSILSIFEIERITENTIEELPDQCKSIFKLSR
                     INGLKNQEIADKLDISVRTVETQIYRALKILKSRLKDYLVS"
     gene            18999..22400
                     /locus_tag="ACZPB4_06780"
     CDS             18999..22400
                     /locus_tag="ACZPB4_06780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HIR1097958.1"
                     /translation="MCLTFFQPYTVAASAQIISLNITKGTITEVFKAIEDQSEYKFFY
                     NDNQINLNKRVDVNIHEESIEQVLNNVFRGTDITYKIVKNHVVLTNKTMKDTELPSTN
                     QNRKRLTGQVVGQDGEPLIGVNVVVKGTTIGSMTDMDGNYILENVPSNATVEFSYIGY
                     LQQSINVGNKSNLNVTLAEDTQKLDEVVVVGYGSFKKRDLTGAVSQVKGDEISNLPLR
                     SAADALQGKAAGVTITSSSGSPGSLGNVRIRGVGTINNNDPLYVVDGLPQGDIGWLNA
                     RDIESIEVLKDASAQAIYGARAANGVILVSTKRGASGESYRSNIEFDMNIGFQDVVKT
                     YDMLDAEGFMEYKNRAYAASGKALIDDFATPEKREQILTFLGKNGGRSGTDWWKESTR
                     KPKEAISQNYNLAFSGGMKKLRYRASFGYMDQQGILKGSDYERLSGRLNVDSEVTKWL
                     NLSANVNVTYESRRNLDENNSYTATVFSTLAADPITPVYRDNLVDIPDFLQNRIMGGY
                     EPTNPWSRYTGVIYSNKPNTVGQVDRSALNQWHGIATKSNISGEVKLLPFLTFKSSIA
                     LDLVRNQSDSFRPSYYLDGDEYSTYAGASRSVANKDYWVFDNYLTYNQKFDKHAVTAM
                     VGTSAEKERYEEIYAYKEGQVNNNPNQQIINAGTMNPAASGYYATSTLNSYFGRVFYS
                     FDNRYMITANIRWDGSSKFADGNRWGYFPSVSAGWNFSEESFMKNLEWLSQGKLRAAW
                     GEIGNQTISSGAYMNTFGNGSYYLFGNPYQTNLYAGRTQVGNPDLKWETTRQLDFGLD
                     LAFFQGSLRATFDYFDRQTSDMLVQVPVPSSLGFPNTPWMNAGSVSNKGFEVTLGYDG
                     KIGNDFQYHINGNVSTYKNKVKSLGSGANIPGKGIHLGYFSYTMTEPGQPIGYFYGYK
                     TDGVFQTQEEIDNYKNNGQMVMPNAKPGDLKFQDLNKDGKLDDEDRTMTGNPHPDFTF
                     GLTLGAEWKGFDISAFFQGSVGNDILNILKYDIYSGTGWYNAPKDILTTYWNGPGSTN
                     ENFAIDADSRMNLEMSDWYVENGSYVRLKNLTIGYTLPSEWTKKITINNLRFFVAAQN
                     LFTITGYSGLDPEIGEINNSPLYKGCDMGFYPQPRTFMFGLSLKL"
     gene            22418..24064
                     /locus_tag="ACZPB4_06785"
     CDS             22418..24064
                     /locus_tag="ACZPB4_06785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RagB/SusD family nutrient uptake outer membrane
                     protein"
                     /protein_id="HIR1097959.1"
                     /translation="MKSIVNIGKLLVSIACVGALTTSCNSDFLDRPPLGTLDEVTYLS
                     TKDAGYKLLVNCYQPLQDSWNYQDMKFVLGDQLSDDCSKGGSDAGDRVRITEIARGTP
                     MATNQVLSDLWTHRYQTAISACNVFLSLITPESELIDDAGGLVSTETKQRWIAEAQFM
                     RAFYYYDLATIFQNIPLIDKPMEVVDKSTITKSSKEEVMNFILKDLNTAIAEPNLPNA
                     KSLPTSEIGRITKEAAMAFRARVLMFYGNYGEALKDLKTVVESGSYELVDDYEKLFNN
                     ATEGYMSKESVFITLRSYIPSYTSGSVCPQMNVGRGIAGGWGGECPTKDLVDEYEVGD
                     PRLVHTVLSSGDIFVKNDGSEEVHDYSGYDNFPQQHSRKQYPDFSRRPLNDLLNTDWT
                     HYHIRYADVLLMYAECLIETDGDKQLAADLINQVRYRAFVTTSLTDSYAKYRKFNLKE
                     SDRVTEDTFNAKYKVKASDNLRAAVRHERRIELAGEGLRFYDLIRWGTFVSTMQKFGK
                     TDEGKYSGAGTLVTDKTYPYPIPQSEIDYVGGALTQNDNY"
     gene            24235..24891
                     /locus_tag="ACZPB4_06790"
     CDS             24235..24891
                     /locus_tag="ACZPB4_06790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HIR1097960.1"
                     /translation="MSYNIRIGIGMDQQTNLKRIAEVINKIQPDYVGLQEVDSVCERS
                     GWINQYAELARLTGMYPIFAPATERSKGLYGIAALSRKKPRSYQYIPLPGKEEPRTFL
                     CLEYPNYTLCNTHFSLDPDSRLASIRLINETMKSENKPILITGDFNMEPDSKEFKTMK
                     QTWRLLSDPTLETYPSDHPRLRLDYIFGDLRHEFRIINDQVIDIQSSDHLPIYIDVLF
                     "
     gene            25052..26119
                     /locus_tag="ACZPB4_06795"
     CDS             25052..26119
                     /locus_tag="ACZPB4_06795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005641351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4831 family protein"
                     /protein_id="HIR1097961.1"
                     /translation="MKNIIIIASLLLGMPLMAQTKVVKKNAVKANNFGITYSLPKTSL
                     VVDAEVTKVTCKAGPYYQYAEKYLGVKDAVTEDKIYFDLGKISLINRGLPDADNTYIV
                     EFKQGTVAPYAYLTEDGLLCSINAEYTPVESELDAAKKNKGSQQKVTDTSVFSEELLM
                     AGSTAKQAEVAAKQIYRIRESRLNILTGEADNLPPDGEAMKLVIQQLEEQEKALTNLF
                     TGILTKETEHYEVSIIPHDNLDKEVLFRFSKQLGIVDADDLGGTPVYMNLKATERAPI
                     LDAKEAEKKDKSLKGIVYNVPGKASIEILMNKKTLYKGEAQITQFGTREGLAPVMFED
                     KKAPVKVLFYPETGAIKQIIQ"
     gene            26146..27801
                     /locus_tag="ACZPB4_06800"
     CDS             26146..27801
                     /locus_tag="ACZPB4_06800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:1904680 - peptide transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015833 - peptide transport [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HIR1097962.1"
                     /translation="MLQGQPKGLYALALANTGERFGYYTMLAIFTLFLQAKFGYTAAE
                     TSTIFASFLAFVYFMPLIGGMMADKFGYGKMVTSGIIIMFVGYLLLAIPTDAASGKIM
                     MFGSLALIACGTGLFKGNLQVMVGNLYDAPEYRSKRDQAFSLFYMAINIGAMYAPTAA
                     TKMTDWMLGKYNLFYESQIPALAHQFLNGTISAENKEALAALQSAQGFTGDMATFCST
                     YIEKLSEAYNYGFGVACISLIISMAIYMGFRSTFKHADVNTKQAKASHAPQEELSPAE
                     TKQRITALLLVFAVVLFFWMAFHQNGLTMTFFARDYTANQVTGLDRIGFDVINLTLLV
                     IAVYGGFAIAQSTTSKGKTIAGIVTVAALAALGIKYMAMPETVTILPQTFQQFNPFFV
                     VVLTPVSLAIFGYLANKKKEPSAPRKIGLGMMIAACGFLILAIGSMGLPTPDALAADS
                     KLQVLVSPNWLISTYLVLTFAELLLSPMGISFVSKVAPPKYKGMMMGGWFVATAIGNY
                     LVAIIGYLWGGMQLWMVWSVLIVLCLLSALFMFSIMKKLDKVA"
     gene            27819..>28180
                     /locus_tag="ACZPB4_06805"
     CDS             27819..>28180
                     /locus_tag="ACZPB4_06805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097963.1"
                     /translation="MRKSYTYRSQALRFRRWSRKAYAAFISVQRAVTIGQLSFSVADR
                     FEKKNQSLHTGIGTFTDGFSEEDDEERENTEENKRSLAVSHGLFTALLPVLVSNEIAH
                     PAHRVAHYTLYNIVKAGS"
     assembly_gap    28181..28280
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <28281..28742
                     /locus_tag="ACZPB4_06810"
     CDS             <28281..28742
                     /locus_tag="ACZPB4_06810"
                     /EC_number="2.8.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004076 - biotin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0009102 - biotin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin synthase BioB"
                     /protein_id="HIR1097964.1"
                     /translation="CSTHTIEQKMETIHTAREIGFRICCGGIIGMGETMEERIEMACF
                     LQKEGVLSIPLNLLQPIPGTPMENTHILEEEEWLTTIALFRLINPNAFLRFSGGRAQL
                     SEATQRKSLYIGINSAIIGDLLTTIGSKVEEDKVLFTSEGYSLTENTDWEK"
     gene            28739..30019
                     /gene="bioA"
                     /locus_tag="ACZPB4_06815"
     CDS             28739..30019
                     /gene="bioA"
                     /locus_tag="ACZPB4_06815"
                     /EC_number="2.6.1.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004015 -
                     adenosylmethionine-8-amino-7-oxononanoate transaminase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009102 - biotin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine--8-amino-7-oxononanoate
                     transaminase"
                     /protein_id="HIR1097965.1"
                     /translation="MTTTELLQYDRDHLWHPYTSTIDPLPVYPVSKAEGVTITLADGR
                     ELIDGMSSWWAAVHGYNHPVLNAAAKAQLDKMSHIMFGGFTHEPAVELAAKLLPLLPP
                     SLEKIFLADSGSVAVEVALKMAIQYWQSKGIPGKHTFATIRSGYHGDTWHAMSVCDPV
                     TGMHGIFSGSLPIQYFIPQPSVRFGEEWREEAMAPLRDLLERHADEIAALILEPVVQG
                     AGGMYFYSPTFLVRARELCERYNVLLIFDEIATGFGRTGKLFAWEHAGVEPDIMCIGK
                     ALTGGYLTLSATITTKPIADTICSGEAGCFMHGPTFMGNPLACAIASASISLLIASHW
                     QEKVKLIEEQLRAELAPAAKLPEVAEVRVLGAIGVIEMKHPVDMAVLQRQFVEEGIWV
                     RPFGRLVYLMPPFVISTYELSRLTSGLLRVLTHN"
     gene            30050..>31080
                     /locus_tag="ACZPB4_06820"
     CDS             30050..>31080
                     /locus_tag="ACZPB4_06820"
                     /EC_number="2.3.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008710 - 8-amino-7-oxononanoate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0009102 - biotin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="8-amino-7-oxononanoate synthase"
                     /protein_id="HIR1097966.1"
                     /translation="MKSYNEQLTALRVSGNLRHLPEVEHQGIWILKEGMRMLNLSSND
                     YLGLASRQDLQEEFQASTQDRFYPYSSSSSRLLTGNFSVYTKLEKQIARSFDREAALI
                     FNSGYHANTGILPALADKQTLLLADKLVHASIIDGILLSGSPFLRYRHNDYDQLERLV
                     QKNACQYETIIILTESIFSMDGDVADLNRLIAIKRQYPNILLYVDEAHAIGARGKTGL
                     GIAEEQSCIQEIDLLVGTFGKALASMGAYLVCSRTIREYLVNTMRPLIFSTALPPFQI
                     AWTSFIWEQLPSFTKERENLLAYSRLLAEALTGKGGEISQSHIIPFIVGESEDCVRKA
                     EELQRKGFY"
     assembly_gap    31081..31180
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <31181..31791
                     /locus_tag="ACZPB4_06825"
     CDS             <31181..31791
                     /locus_tag="ACZPB4_06825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF452 family protein"
                     /protein_id="HIR1097967.1"
                     /translation="GWSTSPELFRHLEVPEQTDLWIAYDYRTLAFEEAFAPYKEVHLV
                     AWSLGVWVATRLWAGHRSFTTATALNGTPFPMHDTLGIPTAIFEGTLHHISEEGMRRF
                     NRRMCGDKETFNRYSELSPRPLEEIKEELESLYNQILPEKLESADPRISTFWDQAILS
                     TEDKIFPATNLRNYWQGRCPIQEIKAPHLPFYHYQSWNELWK"
     gene            31782..32543
                     /gene="bioC"
                     /locus_tag="ACZPB4_06830"
     CDS             31782..32543
                     /gene="bioC"
                     /locus_tag="ACZPB4_06830"
                     /EC_number="2.1.1.197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010340 - carboxyl-O-methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009102 - biotin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malonyl-ACP O-methyltransferase BioC"
                     /protein_id="HIR1097968.1"
                     /translation="MEVIEQERIRRRFSQAVNTYDDHADAQKRICAHLVQLLTVYTSS
                     HFRRVLEIGCGSGGFTRLLKQECQIEEWVLNDLCETWQSAIEELFPSATPLFLAGDAE
                     RLAFPGTFDLIASASALQWMKDLPRFLHKLSSTLSPGGMLAFNTFTPDNLHEIKELTG
                     EGLTYPTAGQLREWLSTYFRIVHEEEGNIALTFRHPLEVLRHLKYTGVTANASCVWTR
                     GKQERFCRDYQERFPSADGGVTLTYRPLYILVVKR"
     gene            32763..33443
                     /gene="bioD"
                     /locus_tag="ACZPB4_06835"
     CDS             32763..33443
                     /gene="bioD"
                     /locus_tag="ACZPB4_06835"
                     /EC_number="6.3.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004141 - dethiobiotin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0009102 - biotin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dethiobiotin synthase"
                     /protein_id="HIR1097969.1"
                     /translation="MNHQTKENVLFISGIDTNVGKTVATGMIAKALAKAGKKVITQKM
                     IQTGCEHVSEDIEAHRQIQGLPFTDEDTQGLTCPYIFTYPCSPHMAAAKDGRRIDLET
                     ITQATRRLRETYEYVLLEGAGGLMVPNDMESLTIDYVKEQAYPLILVTSGKLGSINHT
                     LLSLYACERYGIEVKAIVYNQYPSIDPLIEANTLEYLKAKFPEIPLILLPEMKKGSEE
                     LPDIRPLL"
     gene            complement(33451..33843)
                     /locus_tag="ACZPB4_06840"
     CDS             complement(33451..33843)
                     /locus_tag="ACZPB4_06840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YkvA family protein"
                     /protein_id="HIR1097970.1"
                     /translation="MDTRKIEDVPFEEVHEIQRYGTYFSEKSFWKKIERVAKKVGATV
                     LRPVFTLYYMLQDEKVPLQHKAYIIGALGYFILPFDLIPESVLPIIGFTDDVAVMTFV
                     LKMVKDSITPEIRRKADQKILDLFPDPA"
     gene            34081..>35987
                     /locus_tag="ACZPB4_06845"
     CDS             34081..>35987
                     /locus_tag="ACZPB4_06845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010992007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SusC/RagA family TonB-linked outer membrane
                     protein"
                     /protein_id="HIR1097971.1"
                     /translation="MRNVKTWGILFLCLLLLPGVAYAQKRQIEGTVISQEDKEPLIGA
                     TVIVKGSLSGAETDLDGHFTLEVDPDAKFIIVDYIGMKQTQVPIPKSGILNVALQPEA
                     MNLDEVVVTGYGNFSRSSFTGSANTLRADLLKEMPVVSIEQKLQGMTSGVNITGSSGQ
                     PGANASIRIRGMGSFNASNEPLFVIDGVPVTSGNLSTGSGSEASYMNNAKTNIMSTIN
                     PSDIENITVIKDAAAASLYGSRAANGVILITTKQGSKGRTRVTLNASAGFSDAAVDFR
                     PTLNGEQRRELLYEGLVNYAQDQIAKDPASFTQTPEEYANANIGAYTSVPALGYTDWK
                     DVLMRQAVHQNYEASVSGGSENTTVYSSLGYQKQEGLVENSSMERYSGRFNVQQKIGK
                     RGEAGANLMFSQVNQEMNEERTSSINPFYCMAVATPPSYPVFNEDGSYANTYPGTNVN
                     PLRDMRTDYNRVRMTRIFGTAHGAVEIIKGLKLKEVLSYDYSIQKDARYFNALSGAGP
                     KSGSDAQSSKGFIEYGKLISSTSLNYVRTFANKHHLDVLAAYEAESFQTDKAAGEKSK
                     MPSDQLFEPDNAAVINSFVSSTQDYRLLSYLTRLNYDYDNRYYIAGSFRRDGSSRLAP
                     EHRWGNFWSVSG"
BASE COUNT        10120 a         8674 c         7867 g         9126 t
ORIGIN      
        1 taagactaat ttcaatgatg tcaaagaaca atttaatccc cttattccgg gattatttga
       61 ttaattaata actcgtcccg attttaacgg gacactagtg aatcaaacta ttaaactatg
      121 gatatactaa attctcattt acctttgtct ataactactc aaagcaacta caaatgacac
      181 aaaaagaatc tatccgctta ttcgaagaaa gaaaagttcg cgccatatgg gatgacgaac
      241 aagaggaatg gtatttctcg atcgttgatg ttatatctat tttaacagat agccccaacc
      301 ctcgaaaata ctggagtgta ttaaaaacca gattgaaaag agaaggtagc gagttgacta
      361 caaattgtag tcaactgaaa atgcaggccg ctgatggcaa gaaatattta accgacgtag
      421 ccaataccga gcaactcttc cgccttatcc aatcagtacc atctccaaaa gcagaacctt
      481 ttaagttatg gatcgcccaa gtagcgaagg aacgtttgga tcaaatgcaa gacccggaat
      541 tgtctatcga gcaagccatg gccgattata aacgattggg ctattcggat aattggatca
      601 accaacgatt gaaatccatc gagatacgga aagatctaac agacgaatgg aagaagagag
      661 gactggaaga aggcctccat ttcgctacat taaccgacat aatctataag tcatggtccg
      721 acatgacctc caaggaatat aaacgattca aaggattaag aaaagagaat cttcgagata
      781 atatgacaaa caaagagctt gtattaaaca tgctggccga gttatctacc aaggaaatat
      841 cagaagcatc ggaaccagac acctttagcg agcacataaa tgtcgcccaa caaggaggcg
      901 aggtggctcg taacgcccga ttagagctgg aagccaaaac cgggaaaagc gttatctcac
      961 cgctcaacgc ccaaaagata attagcctaa aaaagggaga gaacgagcgg gatgtatgac
     1021 atccaatgat aagataaaca atatttttcg tacctttgca tcctcaatcg caatttaata
     1081 ggtatacgaa atatgataac agttaacaat ctggacgtac agtttggaaa acgcatcctt
     1141 tttcaggatg tgaacatgaa gtttacaccg ggcaattgct acggtattat cggtgctaac
     1201 ggggccggaa aatctacgtt tctccgtgta atcagcaagc aattagaccc taccagaggt
     1261 agcgttaacc taggaccggg cgaacgtctt tccgtattga gccaagatca cttcgcattc
     1321 gatgaatata cggttatgga taccgtattg atgggacata cgaccttatg ggaggtgatg
     1381 agcgagaaaa acgcccttta cgagaaacct gatttcagcg acgccgacgg tatccgcgta
     1441 tcggaactgg aagagaaatt cgccgagatg gaaggctgga acgcagagag cgacgccgcc
     1501 aacctattga gcggactagg catcaaggag gatttgcatt atatgtatat gaaggacttg
     1561 agcggtaagc agaaagtacg tgtcttattg gcccgtgcct tgttcggaca gcccgataac
     1621 ctattattgg atgagccgac gaacgacttg gaccttgaga cggtttcttg gttggagaat
     1681 tatctctcta atttcgagca taccgtattg gttgttagcc acgaccgtca cttcctcgac
     1741 tccgtttgta cgcataccgt ggatatcgac tttggtaaat tacaattatt cgccggaaac
     1801 tatagcttct ggtacgagtc tagccagtta gcccttcgtc aacagcagaa ccagaataag
     1861 aaagccgagg agaagaagaa agagttggaa gaatttatcc gccgtttcag cgccaacgta
     1921 gcgaagtcca agcagaccac cagtcgcaag aagatgttgg agaagctgaa tatcgaggag
     1981 atcaaaccgt cctcacgccg ctatccggga atcttgttca cgcctaaccg cgaaccgggc
     2041 aaccagatcc ttgaggtgaa aggattgtcg aagagtatcg acggacaggt attgttcaag
     2101 gacttgaact tcttcgtgga gaaggatgac aagatcgtat ttatcagtca cgaccctcgt
     2161 gccatgaccg ccttgttcca gatcatcaac ggtgaggaga aagcggatgc cggtacgtat
     2221 cagtggggac agacgatcac gacctcttat cttcctctcg ataactccaa atatttcaat
     2281 acagatatca acctgctcga ttggttatgc cagttctcgc cggatactaa cgaggtattc
     2341 ttgaaaggct tcctcggacg tatgttgttc tcgggcgagg agcttatgaa aaaggtaagc
     2401 gtactttccg gaggtgagaa gatgcgttgt atgatctcac gtatgatgct caccgacgcc
     2461 aactgcttga tcttggatac tccgaccaac cacttggact tggaatccat ccaagccttc
     2521 aataatacat tgaagacatt caagggaaat atcctgttct ccagtcatga ccacgagttc
     2581 atacagactg tatcgaaccg tatcatcgag ctgactccta acggtatcat cgataagatg
     2641 atggattacg atgattacat cacagatccg gctatcgcgg agttacggga aaagttatat
     2701 tcgaaatgaa aaaaagatta ttattcatac taatcgtttt tatcgcatgg ctaccggttt
     2761 ttgttattca aaaaccggta tttatgtttt atcagcatgc gttgtccgag gcttgtacct
     2821 tcacggactt cctacaggtt atgcttcatg ggctgaagct ggattgtacg atagcgggat
     2881 accttacggc catccctctc ctattgactc tagtatcagt ttggcttccg ggcgcttggt
     2941 tgaagaaggt attgaaaggg tacttcttga tcatgggaat tctggtatct gcgatcttct
     3001 ccgtagatgt ggctttatac agcttttggg gattcaggtt ggacgctact ttattcttct
     3061 acctgcaatc gcccgccgat gcgatggcga gtgttccgtt gggattgttc tttatccaat
     3121 tattggtatt cgtggcatat gcgctaggta tctatgcttg gttcaccttc atcctccggt
     3181 tcgcaccagt aaagcctagc tttccaccta cgggattgga acaattggga agtactttcg
     3241 ccatcctctt agcgggggga atattgttta ttccgatccg gggaggcgta actacgtcta
     3301 cggcgaatgt cggcatggtt tatttcagcc agaaccagtt cttgaatcat tcggcgatca
     3361 acccgtgttt cagtctgata gcctcattga gtaagcaaca ggattttgcc tcgcaattcg
     3421 atttctaccc ggaggaaaag cggaaagcct tattcgatac gctcattcaa gcccaagact
     3481 ccttatgccc gggagattcc atacctacag agcctgtcaa gctattgaca acgactcgtc
     3541 ccaatattct cattatcatc atggagagtt tcacggcaaa tgctatcgag gctgttggcg
     3601 gtgagccggg aattacgccg aacttgaatc ggctgagcaa agagggtgta ttattcacga
     3661 acctatatgc caactcgttc cgtaccgatc gaggcttagt ctccgtattg aacggctatt
     3721 tagcccaacc caccacctcc atcatgaagt atccggtgaa aagccagacc cttccatcta
     3781 tcgcaaagag tcttaacaaa gaaggatata cggcggatat gctctatgga ggtgatatca
     3841 atttcacgaa tatgcaaagt tatttctata gttccggcta cagcaagata acggcagacc
     3901 gtgattttcc cttgagcagc cgtctgagta aatggggagc aaacgacgat atcacgttct
     3961 cgcatcttta cgaggatatc aagcaaagac cagtcgacgg caaaccttgg ttaagtacat
     4021 tcctgacatt aagtagccat gagccattcg aggtcccgtt tcaccatttg gagcatcctt
     4081 atctaaactc cgtcgcgttt acggatagct gtatcggtaa tttcattgat acgttcaagg
     4141 aactgccggc atggaaaaat acggtagtca tctttgtctc cgaccacgga taccgttacc
     4201 ctgaaaacat gcaggagtac ggacctttac gtttccacat acctatgcta tggctaggcg
     4261 gagcgatcgc cgaacctaaa gtgatcgata cgtatgcgaa ccaaaccgat ttggcagcca
     4321 ccttattaaa tcagatgggt ctccccacgg atgagttctc attcagcaaa gatatattga
     4381 atccttgcgt cccgcattac gccttttata cattcaataa tggatttggc tttatagacg
     4441 aatccggtgt ttccgtatac gacaatgaag ggaacaagat tttagtagaa gaacctgaaa
     4501 gcggaaacga gacccgcttg gagaaaggaa aagtcctatt acaaacttta tacgacgatc
     4561 tgggaaatcg atagcgacag atataaaaaa ggccgactta cacaagccgg ccttttttat
     4621 ttatattaaa tatattctta cttagcgtag cttaccgcac gagtctcacg gatcaccgtg
     4681 atcttaacct gtcccggata agtcatctca tcctgaatct tcttagcgat ctcagcggac
     4741 aagttctcgg tgtccttatc gtcaatctta tcagcgccaa cgattacgcg caactctcta
     4801 cccgcttgga tagcgtaagt cttgacaaca cccggatacg ataaagccaa ttgttccaaa
     4861 tcattcaaac gcttgatata agcctctacg atctcacgac gtgcgcccgg acgagcacct
     4921 gaaatagcgt cgcaaacctg tacgatcgga gccaacagcg tctgcatctc cacctcatcg
     4981 tggtgagcgc ctacggcgtt gcaaatatcc ggtttctcct tatatttctc gcaaagcttc
     5041 atacccaaga tagcgtgcgg caattccggc tcatcatcgg gcactttacc aatatcatgt
     5101 aacaatccgg cacgtttcgc tttcttcggg ttcaagccca actcagaagc catcacggca
     5161 caaaggttgg ccgtctcacg agcatgttgc aacaagtttt gtccataaga agaacgatac
     5221 ttcatcttac cgatcatacg aatcaattcc ggatgcaaac cgtgcactcc caaatcgatc
     5281 acggtacgct taccggtctc tacgacctcg tcttccactt gcttcttcac cttcgttacc
     5341 acctcctcga tacgagccgg atggatacgt ccgtcctgta ccaattgatg caaggccaaa
     5401 cgagcgatct cacggcgaac cggatcgaat ccggaaagaa cgatagcctc aggcgtatca
     5461 tccaccacga tctcaatacc ggtagcggcc tccaaagcac ggatattacg tccctcacga
     5521 ccaatgatac gtcctttgat ctcgtccgat tcaatatgga acacggtaat agagttctcg
     5581 atagccgtct ccgtcgctac ccgttggata gactggatca cgatcttctt cgcctcctta
     5641 ttagcggtca tcttcgcctc ctcgacgatc tcgttgatgt aagaagcggc ttgcgtcttt
     5701 gcctcatcct ttaaggactc gatcaaacgc tctttggctt cctcggcgga caacccggag
     5761 atagcctcca aatgctccac ttccttctga tgaagtttat ccaaatcttg cttcttcttc
     5821 tccaccaact ccaactgaga agataaattc tcctttacag cctctacctc gttattccta
     5881 cgctgtaact cttcctgacg ttgattcatc gtcagttctc tttgtttcaa tttagtctcg
     5941 acagactgga tcttagcgtt acgctgtgat acctgttttt ccaagtccgc tttcaaatga
     6001 agaaacttct cctttacttc cagcatcttg ttcttcttta tcacctcggc ctccttctcc
     6061 gcctcttgaa gcacggagtc gtacttcgac ttcagaagga aacgcatgcc cagccacgca
     6121 agcaacccac caatgatgaa ggttactatc ggtatgatta tatacattcc aaccatttaa
     6181 ctaataattt aagattcatt tatttatata caaaaaaagc actaccatca cacggtctca
     6241 ccgtgcaaag cagtgcggaa actctcttct tacaatatgt atgttatttc ttcagatatc
     6301 cttccaactc ggttgtaagc tcctgtatct tatccgtaaa aggatttgta tcattccgtt
     6361 tttccaactc cagattatgc atcgagagtt gaaaagccac catggctaac aaatctttcg
     6421 tatccacctc gaccgcgaaa tgctgcctgt attgaagaat cttgctgttg atctgatcag
     6481 cggcggcacg tgccaactct tcctcatgac gtttgatcgt aagcggatat ttctttccgg
     6541 ctatcactat atttataaga aattcttcgt ccatcgcttc tattcattta aaagtgcgat
     6601 gcacttgtct acttcccgca ctaattttga taaccgcatc cgggcgttct tcatctcttc
     6661 ctcgttcgtg gaaacaattc gcgccgtcag catgttatca catttggcat tcaatccttc
     6721 aatcatatcc ttcgcctgcc gcaactcctc gtctttaagg ctcaaagcag ctgtaagttc
     6781 gtcaattcta cgtttctgct gatcgcataa cgccatcaaa tcacgaactc taacctcaaa
     6841 tacagctaac aatctcttat gatcttcggt catttcacac caaattctac acaaaagtaa
     6901 gtttttgaat tgaattaacc aactgtagac ttaattattt tgacagaaaa cgtatggaca
     6961 aataaaaagg ccgtccaaaa aaatcgaaca gccctcccta attcttgtaa acgttcctct
     7021 tgtttacact aaagaaacat acatttcacc ttcaatctcc tcgaaagcta atttaccttc
     7081 tttcgccaac caaccaaaag cggcgtacat atctttttcc gctttaatct tcgtggcttt
     7141 cttcactgcc ttaaaactca ttttaccgcc ttcatttaaa acgttccata caaggccggc
     7201 gtttgtacca attaattcaa tcattttatg ataacatttg attactgggg acaaatttat
     7261 agattaaatg attaaaacaa aagattatag atgtttttta gcataaaaga tggacatttt
     7321 tcgctttgta aacaatatta acacggttat aacgttattt ttcctctgtt ttctcggcat
     7381 atcagttccg cttccacgtt taccgctgag acatatcttt ttaataagtc aaccgagtaa
     7441 ccacccgctt ccaataagcc ctccttaccg gaataaccat tcagaatcat taacaatgaa
     7501 gtggtcgaca tttcaatctt ggtacgttcc tcatcgctgg taggcgttcc gacacccgct
     7561 actccatccc tgtagactgg aagaccggcg atattcaatt caccacgtcc gataccgtga
     7621 taaatttccc cctcttttcc gacacctagt tccaatccgc ctacaatctt atccgcgtca
     7681 aatcctccga tagaataacc gctacggata gaaaccagat tgacgatatc caccaaggta
     7741 tctatcttat ataaaggaag cccgcgaagt atccgccgtc ttaacgcctc ggcggaaggg
     7801 cgataccgat tcgggtcttt ccccagacgt ttataagcct gacgggtagc gaaaatagga
     7861 gtccacttat taatatcctc tatcttacag gtagaacgga tgtcctcctc aacacgggtt
     7921 atttcttccc aaagtcgttc atcgggctcc gtgttcttta cttggcaggc gatagccaac
     7981 acgtgaagat cggggcaagc ctccgatatc tcagatgaaa gagtgattga aatcatgtct
     8041 attataagtt tgagccaata taactaagat tttttcaagc atatcccggt aaggatccgg
     8101 ccgcttttga caccgaggcg acgagcggag aaataatcct cataccgaat ataagtacag
     8161 atgccagcga tctctatatg ctcggagagc aatcctgcct ctaacaattg taaacggttg
     8221 gtttcccata gatcgatatg cgctttttga gtctccgcat tacgtcgcag aatccgctcc
     8281 attgggaagc ccgccatttg aaaagctttt acgacttcct ctcccacctc aaatgccgct
     8341 tgactgatag agggacctat tccggcaacc aattgagtag gatcgcaatc gtatgcctcg
     8401 atcatcaagc ttgccgcctt acgagctatg tgtaaaaccg taccccgcca acccgcatgg
     8461 acggcagcta ccactttacg atctggcgca tataacaaga cagggacaca atccgccgta
     8521 gatacggcta tacatacatc cggaacattc gtcaccaaag cgtccacgcc ttccaaacgc
     8581 tgcttccgct ctttatcatt cagcgaaagg aaagatgcgt cgatcgccaa tactcgatcc
     8641 tcatgggtct gatgaggtat aaccatattc tctagggaaa tcccgaccgc atccgaaaga
     8701 agttccaagt tcttccggat gaagcccgga tcatcctcgg tataaacgcc cggattcatc
     8761 gaagcatacg ttcccgtact cacgccgcca tgacgtgttg tcgtaaaatg agaaatgtcg
     8821 cggtatccgc ttaacccgga gaaccgcgac acctctattt gcttattttc ttgtatcttc
     8881 atcttcatca tcgtcccagt attcctcgta ttcctcatcc gggtcatcct cgtcctcgtc
     8941 cacggggaag atgtattcgt cgtcgtcctc aaattctaac gtgcttacat ctatattctt
     9001 atggacaatt cgctctgcct catggaaatt ctccttattc agctctttcc ataaaaggtc
     9061 tttcaactcg acaataccca gtcccgtgat agaagatata aagacatacg gaattccctc
     9121 cggcaagtct tgcgacaaag actcgatcaa ttcctcatcc agcatatcgc tcttggtaat
     9181 cgccaataca cggcgtttat ccagcaattc cggattatac ttcaccaact cattatgcaa
     9241 gatctcgtat tctttcttga tatcatccgc ctctgcggga accatgaaca ataacaatga
     9301 attacgttcg atatgacgta agaaacgaag tcccaaacct tttccctcgc ttgctccttc
     9361 gataataccc ggtatatcgg ccattacgaa cgaacggtta tcgcgataac tcacgatgcc
     9421 taaattaggc tccaacgtag taaaaggata attagcgatc ttcggtttag cggcggatac
     9481 gacagaaagc aaggtagatt tacccgcatt cgggaagcct accaaaccga catcggccag
     9541 caatttcaac tgaagaatca ccgtacgttc caatgccggc tcacccggtt gcgaataacg
     9601 gggcgcttga ttggtagccg tcttgaagtt aaaattcccc agaccgccac gaccgccttt
     9661 cagcaacatc acttgctgac cgtcttccgt aacgtcgcaa ataaactctc cggtctcagc
     9721 atcgtaaaca accgtaccgc aaggaacctc gattactcga tcctccccgt ctttacccga
     9781 gctacgcttc gcgctaccac tctcaccatt ggtggccatg atatgacgct catatttcaa
     9841 gtgaaggagc gtccagtaat tccggttacc acggagatac acatgacctc ctctccctcc
     9901 atcgcccccg tcgggacctc ctttcggaat gtatttctca cgacggaagt gagaagaccc
     9961 tcttccaccc tttcctgagc ggcaatagat cttgacataa tctacaaagt tcgattcagc
    10021 catattggtt tatttcaatt attttacgtt attaaccgcc tctttgatac gaccgaagat
    10081 ttcctcgatt gttcccatcc ctttgatggc tacgtgcttg ccttcaccta catagtagtc
    10141 tgccaaagga gctgtttgag tatggtaaac atccagtctg gatttgatcg tctccaagtt
    10201 atcgtcagaa cgtccggata ctttaccgcg ctccaataaa cgcttgatca actcctcttc
    10261 ctctacttga aggttcaaca taacggaaac gtctgttcca cgctcgttca acatcttctt
    10321 caaggctttc gcttgaggga tcgtacgagg gaaaccatcg aagattacac ccttagccgg
    10381 cttcttgcta tccaatacat tcgccaacat atcaacgatc aactcgtccg gaaccaattg
    10441 tcccttctcg atataatcct tagcgatctt gcccagttca gtctcagcct tcatctcgcc
    10501 acgcaatacg tcgccagtag agatatgatc caaaccgtat tctttaataa tcaactcact
    10561 ttgtgttccc ttacctgaac cgggagcacc aaaaataacc acgttcaaca tactattgtt
    10621 tctttattat atataatgta tactatttta ttccacaacc ttgtagatat ccttatatga
    10681 gcggcccaac tcatcataat ccaaaccatg tcccacgata aaatcagcgg gtatctgtaa
    10741 gcctacataa tccggagtca actcgcattt caaggattcc ggcttgaaaa gcatcgttgc
    10801 caatcttaca tcggcggcac cctcgctccg aagcttctcc atcacgtagc tcatcgtaaa
    10861 gcccgtatcg ataatatcct ccaataagat caccatacgt ccgcaaatat cagcctgcac
    10921 cggcatgatc tcattcaata tgcccgtact ggaagttcct tgatacgagg aataacgagc
    10981 gaatgtcagc tcatacggaa catccaactc acgcatcagc tcggcgacaa acataaaagc
    11041 cccgtttagc acacccacga atagaggatt tttcccttcc acatccgctt taatctgaac
    11101 ggccatttta gcgatagccg cctgaatatc cgactccgga ataaacagtt caaattcttt
    11161 gtcttttaga cgaattctgt ccataaatct ttcggttttc gaggggacaa atgtacaact
    11221 ttttcggcga tgcacaaaaa agtgtagcaa cataccaaag tttgttatac atttgtaagc
    11281 agaataaaac cccagacatc tagaattatg attaagatat tcgctacaga caaggtaaag
    11341 gagctcgacc aatatacgat tcaacacgag ccaattagtt cgatcgactt agtggagcgt
    11401 gccgctacga cgttcgtcca tgagttttgc cggcgctact ccaagcaggt ccgcatcgtg
    11461 attttcgccg gtcaaggcaa taacggagcc gacgctttgg ccatcgcccg ccttttgaac
    11521 gaggaatcat accgggtaga gacgtattta ttcaatccga cggagcatct gtccgtagag
    11581 tgtgagcaaa acaagcagcg tctgctcgac atggaacgga tcgaatttac ggaagtggtc
    11641 cgtgactttg agccgccgac gctaaccgac cgagacgtgg tgatcgatgg cttgttcggt
    11701 tcgggattaa accgtcctct caccggaggt ttcgccgcta tggtcaatta tatcaaccaa
    11761 tccgaggcgg aagtcgtagc gatcgatatt ccttccggct tattcgggga agataatcgt
    11821 aagaatgact cggaagcgat catcaaggcc agcttaacct tgacattcgg tttcccgaaa
    11881 ctggcgtttc tttttccgga gaatgagcaa tacgtaggcg agtggaaaat actggatatc
    11941 ggaatccatc cggacgcaat ttatgagacg gcttcccctt actcattggt tacggaagaa
    12001 gatatatcct attcgttaaa gtctcgcaaa cgtttcgccc ataagggaac gttcggacat
    12061 gctttattga tcgccggaag taaaggaaaa atgggagccg ccctattatc tgcgaaggca
    12121 tgcttacgga gtggagccgg actattgacc gtgcatatcc cgacccgagg cgaatcaatc
    12181 ttccaaaccg ctttcccgga agcgatgtta agtttagacg caaatccgga ttatttctct
    12241 acggttcccg agataggtag ttactccgct gttggtatgg gaccgggact cggacagcat
    12301 ttagaatccg cagcagcgat cgaacgtatc ctgcaatcta gcacaaaacc agtcgttatc
    12361 gatgcggacg ctattaatat aatggcatcc aacaaggact tattcaataa gatcccgcca
    12421 cggagcatcc tcactcccca tccgaaggag ttcgaccgga tagcgggtga aagcacgaac
    12481 tcatacgacc gtttgatgaa agcgcaatct ttcgccgccg aacataagat ttgtatcgta
    12541 ttgaaaggtg cttataccgc tatctgttct ccggcaggaa acatttattt caatagttgc
    12601 ggaaatccgg gcatggcaac cgccggtagc ggagatgtgc tgacgggtat catcctcagc
    12661 ttattggcgc aagactattc tccggaaaca gccgctgtag tcggagtatt cttgcacggc
    12721 acagccggtg atctcgccgc cgctttccgc tcggaagaga gcatgatcgc cagcgacatc
    12781 acggatatgc tcggaaaagc gtttaagcaa atcaaataaa tccagcaaaa acaacgggcg
    12841 tttttactct cgtttgttac aattactacc gctattccat atattatacg gacttacagt
    12901 gtacatatag aatggtggta gtaaattttc atggtacccc aacgcctttt gctatcacat
    12961 ttcaaccttt tcttactcac tcaataaatg tcggcgatat cttttatgac aaagctctgt
    13021 aaagtagagt tattgtaact tttaaacatg tataattgta tccctatcat tttatagaaa
    13081 aacacgtaca tgaatttttt taaacatgta cgactttttt cgaaaacacg tacgtgtttc
    13141 agcataaaca tcatgatatt ttcacaatac tgattatcaa cactttaaat aaagtattcg
    13201 attactggct tattgtagta ttttctgtaa agaaaagctt cagtcgttga taccataact
    13261 attacagcaa catttggcta catcatataa tgtatttagt gtatccaaat cagatatact
    13321 gcgttggcga tgtttgtata tattacttgg caaagtcagt actactgcgt ttgccgacta
    13381 ataaatgacc gattgccata cacttccgtt aaaataaata aaaaaggaaa aagagcttac
    13441 gtatcccttg ccccagagtt gtctcatata taaaacaccg acaaatttgt attaacaata
    13501 aagctatacg tacatgaaaa taacaatcgt atcgttcgca atggcagctg ctttcggttt
    13561 aatcgcctgt gataacacga agcataacac attgaccgaa caagagaaag cggaaggttg
    13621 ggaacttcta ttcgatgggg aaaccttgga tggctggcgg gattataacg gaactgcctt
    13681 gaccggacct tgggaagttg taaacggaac catccaagcg gacgggcaag gtagcgatgc
    13741 cagcggatac atcgtcaccg acaaggctta tgagaatttt gagctttcgt gggactagaa
    13801 aatctcgaaa ggaggaaata gcggtttatt atatcatgtg gtagaacgtc ctcaattccc
    13861 ggttccctac gttaccggtc ccgagtatca attgattgat gatatcaatt tcgcggagcc
    13921 attggaagat tggcaacgtt gcggagtgga ttacgcgatg tatttaccgg acttcaacac
    13981 gataaaagta catccggccg gcgaatggaa caactctaag attatttttg acaacggaca
    14041 tgtcacctac tttatgaacg ggcacaaaac cgtagagttc gatgcatggt ctgatgattg
    14101 gttctcccgt aagaacagcg gtaaatgggc gaacgctcct gaatacggat tagcgcataa
    14161 aggcttgatt tgtttgcaag accacggtta tcccgcatgg ttccgtaata tcaagatcaa
    14221 ggaacttccc cgcaagacac gagaggctcg tttattcaac ggcgaggaca ttacaaactg
    14281 ggataaatac ggcacagaat tatggtatgt aaaagatggt ttattagtat gcgaaagtgg
    14341 cccggataaa caatacggct atctagccac ccgggaatat tacgacgatt ttgaccttac
    14401 cgtggaattt aaacaggaag cggatggtaa ttctggcgta tttattcgtt cctttgtaga
    14461 agaaaaagat gtaaaggtaa acggctggca agtggaagtc gcccccaaag gctttgacac
    14521 gggcggtatc tacgaatcct acggacgagg atggttgata cagatcccgg acgagaagga
    14581 gaacatccta aaacaaggag agtggaacac gatgcgtatc cgggtacaag gagataatgt
    14641 acagacttgg ctcaacggag aggagatggt aaacatccgg gatgaaaaga tcggagccgg
    14701 tcaagggcgt atcgctttgc aaatacatga tggtggcggc atcaaggttc tttggcgcaa
    14761 ccttcattta caaacattat agaatatcgt tttcttaaaa tttaatagtt atgaaaaaca
    14821 tttcgagaag aagtttcctc aagaccggag ccgtagcggc agccggacta acgatcgttc
    14881 cgggttctgt actcggtaaa tcctttggct atacagctcc tagtgacaaa ctgaatatcg
    14941 cgggtatcgg tgtcggcggt atgggacgtc gtaacctcgc caacatgaac acggagaata
    15001 tcgtagcttt atgcgatgta gattggcact acgcggacaa gaccttcaag gactatccga
    15061 aggctaaacg ctttaaagac tggcgtgtca tgttcgatga gatgggtaaa tcaatcgatg
    15121 cgattatggt agccacccca gaccatacac atgccggcgt gaccgcccac gcaatcacgc
    15181 taggcaagca ttgctatacg caaaaaccgc ttacccactc cgtttacgaa tcgcgtttgc
    15241 ttaccaaact ggcgaagaaa tataaggtag ccacccaaat gggtaaccaa ggtaactcat
    15301 tcgactggtg ccggcagatc gcagagtgga tacagtctgg cgtaatcggc gatgtatatg
    15361 aggtacattg ttggacagac cgccccatct ggccccaagg cttgatgaag ccgaacgata
    15421 ccccgaagtg cccgaagaca ctggattggg atttatggat cggcccggct caaaagcggc
    15481 cttataatcc ggtctatacc ccttggaact ggcgtggatg gtgggacttc ggaaccgggg
    15541 ccttgggcga tatggcttgc catatcatgg acccgttgta ttgggcactc gacttaaaat
    15601 atccgaccag cgtaatcggc agctctactt tgagtaacct gtactcccct cctcacgcac
    15661 agatcgtaac ctatacattc cccgcacgtc cacccaaagg aaatgtcaag atgccggaag
    15721 tgaaagtcta ttggtacgat ggtggtctga tgcctccccg tccggaagaa ttgaaagacg
    15781 ggcagatgat gggcgacgag aacggcggta tcatcttcat cggaacgaaa ggaaagatca
    15841 tgacaggctg ttatggaatg aacccgacct tattaccggt ttccgacatg gaacatttca
    15901 accagcccaa accgacgatc ccgagagtga aaggtggcaa tggagacata tggtccacca
    15961 atgcccatga gcaagactgg atccgggctt gcaaggaatc cccggaaaat cgtacggaag
    16021 cctcatccaa cttccagttc tccggtccgt tcaacgagat ggtcgtgatg ggagtcttgg
    16081 ccgttcgcct ctccggactg caaggtttgc atcgtgagtt gcaatgggat ggagagaaca
    16141 tgcggtttac gaacatctcc ccgaacgata agatcaagat cgtcacggtg gatgatttca
    16201 aggtaattga cggagatccg cgtttcgacc gtcgcttcgc cgagtttaac gctgcggaaa
    16261 tggccaacga atggatcaag catacgtata acaacggttt ctctttgccg gatatgccaa
    16321 gataaacctt ttaataacag ccaaatatga taagacatat ctataaaata atgatagcga
    16381 tcgtttgctg cctattggct attccaagcg aagcgcaaac gaaggccgag aagaacggat
    16441 ggcgtctagg gatgcaatcc tatagtttcc acctgttccc tttgacggaa gctctcgata
    16501 agacacaaga actgggattg aaatacatcg agatttatcc cggccataag ctcggtggta
    16561 aatggggaga taaagtattc gatttcaacc ttgatgcgca gacccagaaa gagatcaagg
    16621 agcttgcggc atccaaaggt atcaagatcg taggaaccgg ggtgtatgta gccgaaaagt
    16681 cgtccgattg ggaaaagatg ttcaaattcg cgaaagcgat ggacctagag ttcattactt
    16741 gcgaaccggc tttaagtgac tgggacttgg tagaaaaatt gtccaagcaa tacaacatta
    16801 agatctccgt ccataatcac ccgcagcctt ccgactactg gaaacctgag aacctgttga
    16861 aagccatctc cggacgcagt caatcgcttg gttcttgttc cgatgtgggg cattggcgtc
    16921 gggaggggct aaaccagatt gattgcttaa agcaactcaa aggtcgaatc atctctttgc
    16981 atttcaagga tatcgccccg aaaaaagcag gagagaatga gcagcacgac gtgatctggg
    17041 gcacaggcat cctagatgta aagggaatgt tgaaagaact caaatcccag aatttcaagg
    17101 gagtattctc tatcgagtat gaatacaact gggaaaactc tgtaccggac attaaagaat
    17161 gtatccaata cttcaataaa accgcaaacg aaatcttata atagggatta gcattaattg
    17221 acaggtagta agcgtatagg cccaagggac gttctcctag cctatacgct ccacctttct
    17281 aataatacac gggaataaaa tggcatctga caacaaaata atcgaattga tcaaacaagg
    17341 agatatagcc gcctttaata ccctgttcaa gtctgtttat ctccaacttt atatacattg
    17401 ccgaaaattt atccccgccc cggaagacgc aaaagacatc ttacaaaacg tcttcctccg
    17461 cttttgggaa aagcgtgaga acatcgatat tcacacgtct ttaaacgctt atttatacag
    17521 ggctatacag aacgaatgcc tcaattacct tcgttctacc ggaactccct atctgattag
    17581 ccataattaa taaatttaag attaataata agatctaaca atgttacgtt ttttatccgt
    17641 attacactaa aaatcatcca tttctcataa gcaagactgt ttttaagatt aataattcaa
    17701 tgatttatta tttgattact atagtatctt tcagtatttg atagcgaata cccgtattcg
    17761 tctttatcac attgagaatc tccgataaat cttcgttgtt acggaaacta ccgctaaacc
    17821 ttaatttttt tatcccttga ttttcataac gaaatacaac gttatagttc ctttccaaca
    17881 actttgttat atcttgcaga tacatcattt taaaagacaa gaaacctcct ctccattgag
    17941 cgaatagttt cttatcgtaa ggtactactt ctatcttatt tctactttta tcataaaccg
    18001 ccacttggtt aggctcaagt aagacctctt gtttagtcaa cgtaggttgt acggcgacct
    18061 tgccattgaa caaggttgtg gttagttgcg agtcttccat ataagcggaa acattaaagg
    18121 ccgtaccaat cgctttcaca tcaataccgt ttgcctttac aacaaatggt aagtctttat
    18181 tctttgcgac ttcaaaataa gcttctccat ccaaataaat gctacgattg gaatggccgt
    18241 agttctccgc atattctaga gttgtacaag agttaagcca aaccctcgta ccatccggta
    18301 attgcaaata gctcttctct cctttgctcg ttactaattt ataatttcca actgtcgata
    18361 agttctcttg attcgtaaga tacaacgttg atagtgaaac acctatgccc aaaaccacgg
    18421 cagcggcata tttcatgtat tgaaggaata gccttcttgt tttcattttg gaaatagttt
    18481 ttttctctat ggatgaaaac aaacgctccc actccctatc aacatctact tcgtctttga
    18541 gactttccgc aattatattt tttatatatt ctttcattgt tttttctcga ttctatatgt
    18601 atgacacttc aaaacgatgt gctacttaca agattgatag atttttgtat tatatttttt
    18661 caagaaacca gataatcttt caatctactt ttcaaaatct taagggctct atatatctgt
    18721 gtttccactg tacggacgga gatatccaat ttatctgcga tctcttggtt cttgagtcca
    18781 tttatacgac tcaatttaaa aatggattta cattgatctg gtaattcctc tatcgtattt
    18841 tccgtgattc gttctatttc aaaaatacta agtatcgaat aaggatcatt atcttccaca
    18901 gcctcttgtt tatccatctc tgatatttca tatcggggaa tgtcaatggt tccggtagaa
    18961 ctaattacag aaccctgaaa aaatcattat ttttaggttt gtgcttaacc tttttccagc
    19021 cgtacacagt agcggcatca gcacaaatta tatccttaaa tatcacaaaa ggaactatca
    19081 ctgaagtttt taaggcgatt gaagaccaaa gtgaatataa attcttttat aatgacaatc
    19141 aaatcaattt gaataaacgg gttgatgtca atatccatga agaatccata gaacaagtat
    19201 taaacaatgt ctttagaggt acggatatta cgtataagat cgtcaagaat cacgtagtac
    19261 ttaccaacaa gaccatgaaa gatacggagt tgccatccac caaccaaaat cgcaaacggc
    19321 taaccggaca agtagtagga caagatgggg agcctctgat cggagtaaac gttgtagtga
    19381 aaggtactac aatcggatct atgaccgata tggacggaaa ctacattcta gagaatgttc
    19441 cctccaatgc taccgttgaa ttctcgtaca tcggctatct ccaacaaagt atcaacgtag
    19501 gcaataaaag taacctcaac gtcactttag cggaagacac tcaaaagttg gatgaggtag
    19561 tagttgttgg ttacggttcc ttcaagaaaa gagatttaac cggagctgtt tctcaagtaa
    19621 aaggagacga gatctcgaac ctaccgcttc gcagcgccgc cgacgccttg caaggaaaag
    19681 cagccggtgt aaccataaca tctagttccg gtagcccagg ttcactcggt aatgtccgta
    19741 tccgtggtgt cggtactatc aataataatg atccgttgta tgtagtagat ggtctacctc
    19801 aaggtgatat cggttggtta aatgcccgtg atatcgagag catagaggta ttgaaagacg
    19861 cttccgcaca agcgatctat ggtgcccgtg ctgccaacgg tgtgatccta gtatccacaa
    19921 agcgaggagc ttccggcgag agttaccgaa gcaacatcga gtttgatatg aacattggtt
    19981 tccaagatgt agtgaaaacg tatgacatgc tagacgccga aggtttcatg gaatataaga
    20041 accgggctta cgccgcatcc gggaaagcct tgatcgatga tttcgccaca ccagagaagc
    20101 gagagcagat ccttactttc ctagggaaaa acggaggacg atccggtacg gattggtgga
    20161 aagagagcac ccgtaaaccc aaggaagcta tcagtcagaa ttacaaccta gctttctccg
    20221 gaggtatgaa gaaactcaga taccgtgcta gctttggcta tatggatcaa caaggaatct
    20281 tgaaaggttc cgactatgaa cgcctctccg gtcggttgaa cgtagactct gaggtaacca
    20341 agtggttgaa cctctccgca aatgtgaacg tcacgtacga atccaggcgc aacctagatg
    20401 agaataactc ttacacagca accgtgttca gtacccttgc ggcagaccca atcactccgg
    20461 tatatcgcga caacctagtg gatatcccag atttcttgca aaaccgaatt atgggtggtt
    20521 atgagccgac caatccttgg tctcgctata caggcgtaat ttactcaaac aaaccgaaca
    20581 cggttggaca ggtagaccgc tccgcattaa atcaatggca cgggatcgcc acgaaaagta
    20641 atatctccgg cgaagtcaag ttgttaccct tcttgacctt caaatccagt atcgctcttg
    20701 acttagtccg taaccaaagc gactctttcc gtccttctta ctatctggat ggagatgagt
    20761 actccactta tgcgggcgcc agtcggagcg tagcgaataa agattactgg gtattcgaca
    20821 attacctaac ttacaatcaa aaattcgaca aacatgcggt aacagccatg gtcggtacct
    20881 ccgcagagaa agagcgctac gaggagatct acgcctataa agaaggacag gtcaacaaca
    20941 acccgaacca gcagatcatc aacgccggta ccatgaatcc cgccgcatca ggctactacg
    21001 ccacgagtac gctgaattct tatttcggtc gtgtatttta ttcctttgac aaccgttata
    21061 tgatcacagc caatatccgt tgggatggat cctctaaatt tgcggatggt aatcgctggg
    21121 gttacttccc ctccgtatcc gccggttgga atttctcgga agagagcttc atgaagaacc
    21181 ttgagtggct gtcacaaggt aagttaagag cagcttgggg tgagatcggg aaccagacta
    21241 tctcctccgg agcctatatg aatacgttcg gaaatggtag ctactacctc ttcggtaatc
    21301 cgtatcagac gaacttgtat gccggacgta cgcaggtggg taatccggat ctgaaatggg
    21361 agactactcg ccaactggac ttcggattgg atttggcctt tttccaaggt tccttgagag
    21421 caaccttcga ctactttgac cgtcagacaa gtgatatgtt ggtgcaagta cccgtgccca
    21481 gttcactagg attccccaac acgccgtgga tgaatgccgg tagcgtaagc aataaaggtt
    21541 ttgaagtaac gctcggatac gacggtaaga tcgggaacga cttccaatat catatcaacg
    21601 gaaacgtatc cacctataaa aataaggtaa aaagcctagg tagtggagcg aatattccgg
    21661 gtaaaggcat ccatctagga tacttctcct atacgatgac agagccagga caaccgatcg
    21721 gttatttcta cggatataaa accgatggtg tcttccagac ccaagaagag atcgacaact
    21781 acaagaacaa cggtcaaatg gtaatgccaa acgcaaagcc gggcgactta aagttccaag
    21841 atttgaacaa agatggtaaa ctagacgacg aagaccgcac gatgacagga aatcctcatc
    21901 cagacttcac ctttggtttg accttaggcg cagaatggaa aggattcgac atctccgcct
    21961 tcttccaagg atcagtcggc aatgacatct taaacatatt gaaatatgac atctattcag
    22021 gtaccggttg gtacaatgct ccgaaggata tattaacaac ctactggaac ggaccgggta
    22081 gtacaaacga gaacttcgca atcgatgcgg atagccgcat gaacttggag atgtccgatt
    22141 ggtatgtgga aaatggttct tatgttcgct tgaagaacct gacaatcggt tatacgcttc
    22201 cgtccgaatg gactaagaag atcacgatca acaaccttcg tttctttgtt gccgcacaga
    22261 acttattcac gatcaccggt tattccggac tagatcctga gatcggagag atcaataact
    22321 cgcctcttta caaaggctgt gatatgggat tctatccgca accgcgtaca ttcatgttcg
    22381 gtcttagttt gaaattataa tcttaaaatg aattattatg aaatctatag ttaacatagg
    22441 gaaattactt gtatcgatcg catgcgtcgg tgcccttacg acaagctgta acagcgactt
    22501 tctagaccgc ccgccattgg gaacattgga tgaggtaact tatctgagta ccaaggatgc
    22561 cggctacaaa cttttggtca attgctatca gcccttacaa gatagctgga actatcagga
    22621 catgaaattt gtcttgggag atcaattgag cgacgactgc tccaaaggcg gctctgatgc
    22681 aggagaccgc gttcgtatca cggaaatcgc ccgcggaaca ccaatggcga ctaatcaagt
    22741 cttgtccgac ctttggactc atcgctacca aacagcgatc tcagcctgca acgtattcct
    22801 gtcgctaatc acacctgaat cagaattgat cgatgatgcc ggaggcttgg tcagcacaga
    22861 aaccaaacag cgatggatcg cagaggctca attcatgcgt gcgttctatt actacgacct
    22921 agctacaatc ttccagaata ttccactaat tgacaagccc atggaagtcg tcgacaaaag
    22981 tacgatcacg aaatccagca aagaggaggt catgaacttt atcctgaaag acctgaacac
    23041 cgcaatcgcc gaacctaatc tacctaatgc aaaaagcctt ccgaccagcg agattgggcg
    23101 aatcaccaaa gaggccgcca tggctttccg tgctagggta ttgatgttct acggcaacta
    23161 cggagaggct ctgaaagacc tgaagacagt tgtcgaatcc ggaagctatg aattagtaga
    23221 tgactacgag aagctattca ataacgccac agagggctat atgtcaaaag agtccgtctt
    23281 catcaccctg cgctcttaca ttcctagcta cactagcggt agcgtttgtc cacaaatgaa
    23341 tgtcggtcgc ggtattgccg gcggatgggg cggcgagtgt ccgacgaagg atttggtaga
    23401 cgaatatgag gtaggcgatc cacgcttggt acacacggta ttgtcatccg gcgatatatt
    23461 cgtcaagaac gatggttccg aagaggtaca cgactattcc ggctacgaca atttcccaca
    23521 gcaacacagc cgtaagcagt atccagactt ctccagacgg ccactaaacg atttattgaa
    23581 cacggattgg acccactatc acatccgcta tgccgatgta ttgctgatgt acgctgaatg
    23641 cctgatcgag acggatggcg acaaacaact agcggccgac ctgatcaacc aagtacgtta
    23701 tcgtgccttc gtgacaacct ctttgacaga tagctacgct aaataccgta agttcaacct
    23761 caaggagagc gatcgagtga ccgaggatac tttcaacgct aagtataaag tgaaagcttc
    23821 cgataatctg cgtgccgccg ttcgccacga acgccgtatc gaacttgcag gcgagggatt
    23881 acgcttctac gacttaattc gctggggcac cttcgtatct acaatgcaga aattcggcaa
    23941 gactgatgag ggcaagtatt ccggtgccgg gacactcgtc accgataaga cataccccta
    24001 cccgattcca caaagcgaga tcgactatgt aggaggcgca ttaacacaga acgataatta
    24061 ttaatcttca atttttatta ctgtagcccc cgcagatagt ccttcttgtt gtctgcgggg
    24121 gtttctattc acgaaatacc ttagaaatcc atgaaacgaa tcttatttct cctaaccatc
    24181 gccctcctaa atttgggaag tggcctatgc aaaacacgac aatcgttaag aatcatgagc
    24241 tacaacatcc gcatcgggat cggtatggac caacagacca atttgaagcg aatcgctgaa
    24301 gtgatcaaca agatccagcc ggactatgtc gggctacaag aggtggacag tgtatgcgaa
    24361 cgctctggat ggatcaacca atatgcagaa ttagcacggt tgaccggcat gtatccaatc
    24421 ttcgcacctg ccacagaacg ttctaaggga ttatacggaa tcgccgcact ctcccgcaaa
    24481 aaacctcgta gctaccaata catacctctg ccgggaaagg aagagccacg taccttcctt
    24541 tgtctcgaat atccgaacta taccttgtgt aacacacatt tctcgctcga cccagactct
    24601 cgcctggcct ctatacgact catcaatgag acgatgaaaa gcgaaaacaa accaatcctg
    24661 atcaccggag acttcaacat ggagccagac tctaaggaat tcaagacgat gaaacaaacg
    24721 tggaggctct tatccgaccc tacgttagag acctacccct cggatcatcc ccgtttgcgt
    24781 ttagattata tcttcggcga cctaaggcat gaatttagga ttatcaacga ccaagtgatc
    24841 gatatccagt cgtccgatca cctgccgatc tatatagacg tgctatttta agctttctcc
    24901 cccggacatc ctcagaatcc cgaacaatgc gaatctagaa attcttaatg ttgtccggga
    24961 ttttcatgca ataagaatac ttccaattgg ttttaagcaa aatatttcct agttttgcgc
    25021 aataatatac agaattaaaa taaactggga tatgaagaat ataatcatta tagctagttt
    25081 actcctcggg atgccgctta tggcacaaac caaggtggta aaaaagaacg ccgtaaaagc
    25141 caataatttc ggaatcacct actcgttgcc caagacctcg ctagtcgtag acgccgaagt
    25201 gacgaaagta acttgcaaag ccgggcctta ctatcaatat gcagagaagt atctaggcgt
    25261 aaaagatgca gtcacggaag ataagattta tttcgatctc ggaaaaatca gtctgatcaa
    25321 ccggggatta cccgatgcgg ataataccta tatcgtagaa ttcaagcaag gtacagtcgc
    25381 cccttacgct tatcttaccg aagatggatt attatgctcg ataaacgcag aatatacacc
    25441 agttgaatcc gagctagatg ccgcaaagaa aaataaaggc tcccaacaaa aagtgacaga
    25501 cacttccgtt ttctcggagg aattactaat ggcaggctcc accgccaaac aagcggaggt
    25561 ggccgctaaa caaatttacc gtatccggga aagccgtttg aacatcttga ccggcgaggc
    25621 ggataattta ccccccgatg gtgaagccat gaaactggtg atccagcaat tggaggagca
    25681 agaaaaagca ttaacaaacc tattcaccgg aatcttgacc aaagaaaccg agcattatga
    25741 ggtaagtatc atcccccacg acaacctaga taaagaagta ttgttccgtt tctccaagca
    25801 gctaggtatc gtagacgctg acgatttggg cggtacccct gtctatatga acttgaaagc
    25861 gacagaaaga gctccgatcc ttgatgccaa ggaagccgag aagaaagaca aatcattgaa
    25921 aggaatcgtc tacaatgttc cgggaaaagc cagcatagaa atactaatga acaaaaaaac
    25981 gctctacaaa ggagaggccc aaatcactca attcggaaca cgggaaggat tagcccctgt
    26041 tatgtttgag gataagaaag cccccgtcaa agttcttttc tatccggaaa ccggcgccat
    26101 aaagcaaatt attcaataag tataaactaa tattatctaa aacacatgtt acaaggacaa
    26161 cctaaaggtc tctatgccct agcactcgcg aacacgggcg aacgcttcgg ttattacacg
    26221 atgcttgcga ttttcacatt attcttgcaa gcgaaattcg gctatacggc cgctgagaca
    26281 tcaacgattt tcgctagctt cttagcgttc gtgtatttta tgccattgat tggcggtatg
    26341 atggccgata agttcggtta tggaaagatg gttacctcgg gtatcatcat catgtttgtc
    26401 ggttatcttt tattagccat cccaacagat gccgcctcgg gaaaaatcat gatgttcggc
    26461 tcgctagcgc taatcgcttg cggtaccgga ttatttaaag gtaacttaca agtgatggta
    26521 ggtaatcttt atgatgcccc ggaatataga agtaaacgtg accaagcctt tagtttgttt
    26581 tatatggcga tcaatatcgg tgccatgtac gcacctacgg ctgccactaa aatgacagac
    26641 tggatgttgg gtaagtataa ccttttctac gagtcacaaa ttccggcact cgctcaccaa
    26701 ttcttaaacg gaaccatctc cgcagagaac aaagaggcac tcgccgctct gcaaagcgca
    26761 caaggtttca ccggcgatat ggctacgttc tgttccacgt atatcgagaa gttgtctgag
    26821 gcatacaact atggattcgg tgtggcttgt atctcattga tcatatcgat ggctatctat
    26881 atgggattcc gctctacctt taagcatgcg gatgtcaata ccaaacaagc aaaggcttcc
    26941 cacgctccgc aagaggaatt gtcacctgcc gagacgaaac aacgtatcac cgccttgctg
    27001 ctggtattcg ccgtggtatt gttcttctgg atggctttcc atcaaaatgg tctgacaatg
    27061 acgttctttg ctcgcgacta tacggccaac caagtgaccg gactggatcg tatcggcttt
    27121 gatgtgatta acttaacatt attggttatc gccgtgtatg gaggattcgc tatcgcacaa
    27181 tccacaacga gcaaaggcaa aacgatcgcc ggcatcgtga ccgtggccgc attagccgct
    27241 ctaggtatca aatatatggc tatgccggaa accgtaacga tccttccgca gaccttccag
    27301 caatttaacc cgttcttcgt ggttgtattg actccggtat cgttggcgat ctttggttat
    27361 ctggctaata agaagaaaga gccgtccgct cctcgtaaga tcggattggg tatgatgatc
    27421 gccgcttgcg gtttcttgat cttggcgatc ggttctatgg gcttgcctac accggacgct
    27481 ttagcggcgg atagcaaatt gcaggtattg gtttctccga actggttgat atcgacttat
    27541 ctggtattga ccttcgccga attattgctt tctccgatgg gtatctcttt cgtatccaaa
    27601 gtggctcctc ctaaatacaa aggtatgatg atgggtgggt ggttcgtggc tacggctatc
    27661 ggtaactatc tggtcgctat catcggttat ttgtggggag gcatgcagtt atggatggta
    27721 tggagcgtgt tgatcgttct ttgtttactg tctgcgttgt tcatgttctc tatcatgaag
    27781 aaactggata aagtggcttg acaattgaaa attagaggat gaggaagtcg tatacatatc
    27841 gttcgcaggc actccgtttc agaagatgga gccggaaggc gtatgcggct ttcatcagtg
    27901 tacagagagc tgttacgatc ggacaattat ccttttccgt agccgatcgc ttcgagaaaa
    27961 agaaccagtc tttacatacc ggtatcggta cgttcacgga cggattttcc gaagaggatg
    28021 acgaggagag ggagaatacc gaggagaaca aacggagcct cgcggtatcg catggactgt
    28081 ttacggcatt actcccggta ttggtatcaa atgagatcgc tcatccggct catcgtgtag
    28141 ctcactatac attatataat atagtaaagg cgggaagtat nnnnnnnnnn nnnnnnnnnn
    28201 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    28261 nnnnnnnnnn nnnnnnnnnn tgttccacgc atacgatcga gcagaagatg gaaaccatcc
    28321 ataccgcccg ggaaatcggt ttccgtatat gctgcggtgg tattatcggc atgggcgaga
    28381 cgatggagga acgaatcgag atggcttgtt tcttacagaa agaaggtgtc ttatccatcc
    28441 ctctcaattt attacagccg ataccgggaa ctcctatgga gaatacacat atcctagaag
    28501 aagaggaatg gctaacaacg atcgcccttt tccgcttgat caatccgaac gcatttctcc
    28561 gtttctccgg cggacgggca caattaagcg aggccacgca acggaaatcc ctatatatag
    28621 ggattaactc cgcaatcatc ggagacttat taacgactat cggaagcaag gtagaggaag
    28681 acaaagtctt atttacctcc gaaggctatt cactcaccga aaacaccgat tgggaaaaat
    28741 gacaacaacc gaacttttac aatacgaccg ggatcatcta tggcatccct acacctcgac
    28801 catcgatcca cttcccgtct atccggtatc caaagcggag ggcgtaacga taacccttgc
    28861 ggacggcagg gagctaatag acggaatgtc ttcttggtgg gcggcagtcc acggatacaa
    28921 ccatccggta cttaacgcgg cggctaaagc ccaattggat aagatgagtc atatcatgtt
    28981 cgggggattc acgcacgagc cggctgtcga gttggccgct aaattattac cgctattgcc
    29041 cccttcccta gaaaagatat tcctagcgga tagcggctcg gtagccgtgg aggtagcctt
    29101 aaagatggcg atccaatact ggcagtccaa aggcataccg ggaaaacata ccttcgccac
    29161 gatccgtagc ggttatcacg gggatacttg gcacgccatg tcggtatgcg atccggtgac
    29221 gggtatgcat gggatcttct ccggaagcct acccatccaa tacttcatac ctcaaccttc
    29281 ggtccgattc ggcgaggaat ggagagagga ggccatggct cccttgcggg atttactaga
    29341 gcggcatgcc gacgagatcg ccgccttgat cttggaaccg gtcgtacagg gggcaggagg
    29401 tatgtatttc tactccccca ctttcctcgt tcgtgcccgg gaactttgcg agcggtataa
    29461 cgtcttattg atattcgacg agatagcgac aggcttcgga cgtaccggaa agttgttcgc
    29521 atgggaacat gcgggagtcg aacccgatat catgtgtatc ggaaaggcat tgacgggagg
    29581 ttatcttacg ctttccgcca cgatcacgac gaagccgata gccgacacga tctgttccgg
    29641 cgaggcggga tgctttatgc atgggcctac gtttatggga aatcccttgg catgcgctat
    29701 cgcttcggcc tcgatctctt tattgatcgc cagtcactgg caggagaaag tgaagcttat
    29761 agaggaacaa ttgcgggcgg agttagcgcc agccgccaag ctacctgaag tcgctgaggt
    29821 acgggtattg ggggcgatcg gggttatcga gatgaagcat ccggtggata tggcggtatt
    29881 acaacgccaa ttcgtagagg aagggatatg ggtacgtcca ttcggacggc tggtttatct
    29941 catgcctcct ttcgttatct ccacgtatga actatccaga ctaacctccg gattattgag
    30001 agtattaacg cataattaac atatctacaa ccgggtaata tatagatata tgaaatcata
    30061 taacgagcaa cttacggctt tacgagtctc cgggaatctt aggcacctac cggaagtcga
    30121 gcatcaagga atatggatat taaaagaggg aatgcgtatg ctgaatctct cttccaacga
    30181 ttatcttgga ttagccagcc ggcaggattt acaagaggag tttcaagcat ccacacaaga
    30241 ccgcttctat ccctactcct cctcatcatc ccgcttgctg acgggtaatt tctccgtcta
    30301 tacgaaactg gagaaacaga tcgcccgctc cttcgaccgg gaagccgcat tgatcttcaa
    30361 cagcggctat catgccaaca ccggaatcct cccggccttg gccgataaac agaccttatt
    30421 actcgccgac aagctggtgc acgccagcat catcgatggc atcttgctga gtggttcccc
    30481 attcctccgt taccgccaca acgactatga ccaactggaa cgcctcgtac aaaagaacgc
    30541 ctgtcaatac gagacgatca tcatcttgac cgaaagcatt ttcagcatgg acggggatgt
    30601 agcggactta aaccgcctga tagcaatcaa aaggcaatat cccaatatcc tattgtacgt
    30661 agacgaggct catgccatcg gagcccgtgg aaagacgggg ctaggtatcg ccgaggaaca
    30721 aagttgtatc caagagatcg atctattggt cggtactttc ggcaaggcgt tagcgtctat
    30781 gggggcctat ttggtttgtt cccgtacgat acgggaatat ctggtcaata cgatgcgacc
    30841 gctcatattc agtacggccc tgccaccgtt ccaaatcgca tggacttcct tcatctggga
    30901 gcaactcccc tcgttcacga aggaacggga gaatcttcta gcatatagcc gattgctggc
    30961 ggaggcttta acgggcaaag gaggcgagat cagccaaagc cacatcatcc ctttcattgt
    31021 gggagagagc gaggattgcg tacggaaagc ggaagagcta caacgaaaag gcttctactg
    31081 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    31141 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn ccggctggtc cacctcgccg
    31201 gagcttttcc gccatctgga agtaccggag cagacagacc tatggattgc ctacgattac
    31261 aggacgctcg cattcgaaga ggcattcgcc ccctataaag aggtacatct ggtcgcttgg
    31321 tctctaggcg tatgggtagc cacccgactc tgggcaggcc accgatcctt taccacggcg
    31381 accgccctga acggtacccc ttttcccatg cacgatacgc taggcatccc gaccgcgatc
    31441 ttcgagggaa ccctccatca tatcagcgag gaaggcatgc gtcgctttaa ccgcaggatg
    31501 tgcggagaca aggagacatt caatcgctat tcggaactct caccacgtcc gctggaggaa
    31561 atcaaggagg aactggaatc tctatataat cagatcctcc cggaaaagct cgaatcagcc
    31621 gatccacgga tatccacctt ctgggatcaa gccatcctat ccaccgaaga taagatattc
    31681 ccggcaacca acctccggaa ctactggcaa ggccgttgcc ccatccaaga gatcaaggcg
    31741 cctcatcttc ctttttacca ctatcaatca tggaacgaat tatggaagta atcgaacaag
    31801 aacggatccg ccggcgtttc agccaagcgg tgaatacata cgacgatcac gcggatgccc
    31861 agaaacggat atgcgcccat ctggtacagc tattgaccgt atacacctcc tctcatttcc
    31921 gcagggtgct ggaaatcggt tgcggaagcg gcggattcac ccgtttatta aaacaagaat
    31981 gccaaatcga ggaatgggta ctcaacgatc tttgcgagac ttggcaaagc gccatcgagg
    32041 agttgtttcc ttccgccact cctctattct tggccggtga tgccgagcga ctggcttttc
    32101 ccggcacgtt cgacttgatt gcctcggcct ccgccctgca atggatgaaa gaccttccac
    32161 gtttcctcca taagctatcg tccaccctat cgcccggagg catgctggct ttcaacacct
    32221 tcacgccaga caaccttcac gagatcaagg aactgaccgg agaagggctc acctatccta
    32281 ccgccggaca attaagggag tggttatcca cctacttccg gatcgtccat gaagaggaag
    32341 gaaatatcgc cctgaccttc cggcacccgc tggaggtgct aagacatcta aagtacacgg
    32401 gtgtcacggc caacgcctct tgcgtctgga cacggggaaa acaggaacgt ttctgccggg
    32461 attatcaaga gagattcccc tcggcggatg gtggggtcac attaacttac cgtccactct
    32521 atatcttagt ggtcaaaaga taaaggtgag gtagatcgcc tcttccgagg tattgatcct
    32581 ttcacctata tgatatgatc gtatcacaag ggtgaaacga tcttttcaca aaggtgatac
    32641 gttcttttca caaatgtgaa aagatcaata gcgcagaaga aaaggaataa atctcttaga
    32701 gacaaggagt aatatccata gagacaaaag attaatcaag caactattta aacaacagaa
    32761 caatgaacca tcaaacgaaa gaaaatgtat tatttatctc cggcatagac acgaacgtcg
    32821 gaaagaccgt agccaccgga atgatcgcca aggcattggc gaaagccgga aagaaagtga
    32881 tcacccaaaa gatgatacag accggatgcg agcacgtatc ggaggatatc gaggcacacc
    32941 gccaaatcca agggctcccc tttaccgacg aggatacgca aggactgact tgtccttata
    33001 tcttcaccta tccctgctct cctcatatgg cggcggcgaa agatggaaga cgtatcgatt
    33061 tagaaacgat cacccaagcc acccggcgat tgcgagagac ctacgagtat gtattactgg
    33121 aaggagccgg aggactgatg gttccgaacg acatggaatc ccttacgatc gattatgtga
    33181 aggaacaggc gtatcccctg atactagtca cgtccggcaa gctgggaagt atcaatcata
    33241 ctttgctcag cctgtacgcc tgcgagcgat acggtatcga ggtaaaagcc atcgtctata
    33301 accaatatcc aagcatcgac ccgctgatcg aggcgaatac cttggagtat ctaaaggcca
    33361 aattcccgga gatcccctta atcctccttc cggaaatgaa aaagggaagc gaggagcttc
    33421 ccgatattcg cccgttgcta taacgcccta tcaagccgga tcaggaaaca gatccagtat
    33481 tttctgatcc gcttttctcc ggatctccgg tgtaatgcta tccttcacca ttttcaatac
    33541 gaaagtcatc accgccacat cgtccgtgaa gccgataatg gggagcacgc tctccgggat
    33601 caagtcgaaa ggcaatataa agtatcctaa agccccgatt atataagcct tatgttgaag
    33661 aggtaccttt tcatcctgca acatataata cagcgtgaag acaggacgca ataccgtagc
    33721 ccccactttc ttcgctaccc gctctatctt cttccagaaa ctcttctccg agaaataagt
    33781 cccatatctt tgtatctcat gtacttcctc gaaaggaaca tcctcaatct ttcttgtgtc
    33841 cataaacgaa tcctattaaa tcatctttca caaagataac aagtagtgta gaaaaattgc
    33901 acatcaaatg aggaaatatt acacaatgcc acctccacac ccgtattcaa agcttttcgt
    33961 aataatctca taagaaaaca attataaaga aatctacagg atttatcaca tctggcacgc
    34021 ctttttcaga taatccttta gttagtatag gtattaataa gacgttttaa acaaaaagag
    34081 atgagaaatg taaaaacatg gggcatacta ttcctatgtc tacttctatt gcccggggta
    34141 gcgtatgcgc aaaaaagaca gatcgaagga acggtgattt cccaagagga caaggagcct
    34201 ctgataggag cgaccgttat cgtaaaaggg agcctgtcgg gagcagagac cgatctcgac
    34261 gggcatttca cgctggaagt tgatcctgac gccaaattca ttattgtcga ttacatcggc
    34321 atgaagcaga cccaagtacc tatcccgaaa agcggtatct taaacgtggc tttacaaccg
    34381 gaggcgatga acctcgatga ggtcgtggta accggttacg gtaacttctc acgttcttcc
    34441 tttaccggtt ccgccaacac tttacgggct gacctactga aagagatgcc ggtggtttcc
    34501 atagaacaaa aactacaagg catgacctcc ggtgtcaata tcacgggaag ctccgggcaa
    34561 ccgggagcga acgcatccat ccgtatccgt ggtatgggct cgttcaacgc atcgaacgaa
    34621 cctttgtttg tgatagacgg agttcccgtc acctcgggaa acctaagtac cggaagcgga
    34681 tcggaggcct cctacatgaa caatgccaag accaacatca tgagtacgat caatccctcc
    34741 gatatcgaga atatcacggt tatcaaggat gccgccgccg cctcccttta cggttcccgt
    34801 gcggccaacg gtgttatctt gatcacgacc aaacaaggat cgaaaggacg tacccgggtc
    34861 acgttgaacg ctagcgcagg attctcggac gcggcggtag acttccgccc gaccctcaac
    34921 ggagagcaac gccgggaact actttatgaa ggcttggtta attacgcgca agaccagatc
    34981 gccaaagatc ccgcatcttt cacccagact ccggaagagt acgccaacgc caatatcggg
    35041 gcatacacct ctgttcccgc tttaggctat accgattgga aagacgtgtt gatgagacag
    35101 gccgtacatc aaaattatga ggcttccgtt tccggtggct ccgagaacac gacggtctac
    35161 agctccttgg gttatcaaaa acaagagggt ctggtggaga actcatcgat ggaacgatac
    35221 tccggacgct ttaacgtaca acaaaagatc ggcaaacgag gcgaggccgg agcgaacctc
    35281 atgttctcgc aagtgaatca agagatgaac gaggaacgta catccagtat caatcctttc
    35341 tattgcatgg cagtagccac tcctccctcc tacccagtat ttaacgagga tggttcctac
    35401 gccaatacct atcccggaac gaacgtaaat cctttgcggg atatgcgtac cgactataac
    35461 cgggttcgta tgacccgtat cttcggtacg gcgcacggtg cggtagagat tatcaaagga
    35521 cttaaattaa aggaagtact cagctatgat tatagcatcc aaaaggatgc ccgctatttc
    35581 aacgcattaa gcggggcggg tcccaagagc ggtagcgatg cccaatcgtc caaaggtttt
    35641 atcgaatacg ggaaattgat ctcttctacc tcgttgaact acgtgaggac attcgccaac
    35701 aaacatcatc tggatgtact agccgcttat gaagcggaaa gtttccagac agataaagcc
    35761 gccggtgaga aaagcaagat gccgtccgac caattattcg agccggacaa tgccgccgtt
    35821 ataaacagtt tcgtatcctc tacacaggat tatcggttgc tttcttatct aacccgcttg
    35881 aattatgatt acgacaaccg gtattatatc gccggaagtt tccgtcggga tggtagttcc
    35941 cgattggcgc cggagcatcg ctggggtaat ttctggtcgg tctcagg
//
LOCUS       DBMDTB010000030        34938 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_496_length_34938_cov_10.139220, whole genome shotgun sequence.
ACCESSION   DBMDTB010000030 DBMDTB010000000
VERSION     DBMDTB010000030.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 34938)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 34938)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34938
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_496_length_34938_cov_10.139220"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(75..2795)
                     /gene="ppdK"
                     /locus_tag="ACZPB4_06850"
     CDS             complement(75..2795)
                     /gene="ppdK"
                     /locus_tag="ACZPB4_06850"
                     /EC_number="2.7.9.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009121126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050242 - pyruvate, phosphate dikinase
                     activity [Evidence IEA];
                     GO_process: GO:0006090 - pyruvate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="HIR1097972.1"
                     /translation="MERKRVYTFGNGKAEGKADMRNLLGGKGANLAEMNLIGVPVPPG
                     FTITTEVCIEYYELGKDKVVELLKADVEKAIANIETLMNSKFGDVANPLLVSVRSGAR
                     ASMPGMMDTILNLGLNDEVVEGLSRKTGNARFAWDSYRRFVQMYGDVVLGMKPTSKED
                     IDPFEAIIEEVKKAKGVKLDNELDVEDLKTLVSKFKAAVKAQTGQDFPTCAYEQLWGA
                     ICAVFNSWMNERAILYRKMEGIPDEWGTAVSVQAMVFGNMGDTSATGVCFSRDAGNGE
                     DLFNGEYLINAQGEDVVAGIRTPQQITKIGSQRWAERAGISEEERIAKYPSMEEAMPE
                     IYKQLDAIQEKLEDHYRDMQDMEFTVQEGKLWFLQTRNGKRTGAAMVKIAIDLLHQGM
                     IDEKTALNRIEPNKLDELLHPVFDKKAEKLAKVWVKGLPASPGAATGQIVFFADDAAK
                     WHADGKKVVMVRIETSPEDLAGMAVAEGILTARGGMTSHAAVVARGMGKCCVSGAGAL
                     NIDYKNKTVDVDGVTLKEGDYISINGTTGEVYVGQVETKAAELSGDFAELMALADKYT
                     KLQVRTNADTPHDASIARSFGAVGIGLCRTEHMFFEGEKIKAMREMILAEDAEGRKKA
                     LAKILPYQKEDFKGIFKAMAGCPVTVRLLDPPLHEFVPHDLKGQEEMAETMGVSVKEI
                     QKRVESLCEHNPMLGHRGCRLGNTYPEITEMQTRAILGAALDLKKEGIEAKPEIMVPL
                     TGILYEFKEQEKVIRTAAEELFKEVGDRIEFKVGTMIEIPRAALTADRIASSAEFFSF
                     GTNDLTQMTFGYSRDDIASFLPVYLEKKILKVDPFQVLDQNGVGQLVRMATEKGRAIR
                     PDLKCGICGEHGGEPSSVKFCHKVGLNYVSCSPFRVPIARIAAAQAALED"
     gene            3402..4814
                     /gene="rlmD"
                     /locus_tag="ACZPB4_06855"
     CDS             3402..4814
                     /gene="rlmD"
                     /locus_tag="ACZPB4_06855"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0000154 - rRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HIR1097973.1"
                     /translation="MARKKKQLPILEKVTITDVAAEGKAIARVNDMVVFVPFVAPGDV
                     VDIQLTRKKNSYAEGKPVYFHEYSAKRAEPFCEHFGVCGGCKWQHLPYEEQLYYKQKQ
                     VYDNLTRIGKVEMEEKLPILGSERTTFYRNKLEFTFSNKKWLTEEEIQSGASFDCMNG
                     VGFHIPGMFDKVLDIHKCWLQDDISNKIRLCVKEYCLSHEGYPFFDLRNQEGFVRTLM
                     IRTASTGDLMVVLVFFHEDVERREALLSHLAERFPEITSLMYVINGKCNDTITDQEVL
                     VFKGKDHIIEEMEGLQFKVGPKSFYQTNSEQAYNLYKVAREFAGLTGNEMVYDLYTGT
                     GTIANFVSRQAKKVIGIEYVPEAIEDAKVNSALNHIENTLFYAGDMKDILTQDFINQH
                     GRPDVIITDPPRAGMHDDVINTILFAEPERIVYVSCNPATQARDLSLLSVKYSVKKVR
                     PVDMFPHTHHVENVVLLEKK"
     gene            4827..6212
                     /locus_tag="ACZPB4_06860"
     CDS             4827..6212
                     /locus_tag="ACZPB4_06860"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008933 - peptidoglycan lytic
                     transglycosylase activity [Evidence IEA];
                     GO_function: GO:0016837 - carbon-oxygen lyase activity,
                     acting on polysaccharides [Evidence IEA];
                     GO_process: GO:0000270 - peptidoglycan metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MltF family protein"
                     /protein_id="HIR1097974.1"
                     /translation="MYRKYVPFLLFLFFLYGCNGNKQEEKEDVSVFVDLPQLKAEGEI
                     TAVTLYSSTSYFQYKMQPMGYEYDLINDFVKSQGLKLNIKVAENPARLIEMLEAGEAD
                     VVAYPIPINNKLKQEVIYCGREDISSQVLIQRANKGDKLLTDVTQLIDKNVYVKPNTK
                     YSERLKNLDEELGGGIHIQKVENDSIATEDLIEMVSLGEIPYTISDDNTARLNKTYYW
                     NINVDLKVSFPQRSSWVVRKSSPDLAKAIDEWASDKTGKHSFKAVTKRYFELSKRPFT
                     ADIPEVKNGHISPYDPLFKKHAKNIGWDWQLLASISYQESHFNPTVVSWAGAEGLMGI
                     MPNTAKALGVTPHELKDPDTGIRTGVDCLRRFRQGFSEITDPEEKVKFTLAAYNAGIG
                     HIYDAQRLARKYGKDPNKWDNNVAEYIRLKNDPEYYNDPVCKHGYLRGSETYNYVREV
                     LERYHYYKKKS"
     gene            complement(6281..7162)
                     /locus_tag="ACZPB4_06865"
     CDS             complement(6281..7162)
                     /locus_tag="ACZPB4_06865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007652960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3078 domain-containing protein"
                     /protein_id="HIR1097975.1"
                     /translation="MKRIFFMTLFVALTTITYGQTDDKGYEEGKWVLKGVTGLNLSQT
                     AMSNWSAGGENSVAGNAYLNGALTHKSGDWLWVTNLALDYGLSKTKSQGMRKSTDNIT
                     LSTQLGYSTNNVWYYTLMGDLNTQFAKGYNYPDKTHYISNFFAPAYSNISVGMEYRPK
                     SNYSVYLSPASTKMTFVEDDYLSKLGAFGVDPGDRFRMEWGAYLKARAELTVMENVNL
                     ITTADFFTPYSDQFGNIDVNWDVLISMKINKFLSATLNTTLKYDNDVKTFEDNGEKRG
                     AKVQFKEILGIGVAYNF"
     gene            7328..7561
                     /locus_tag="ACZPB4_06870"
     CDS             7328..7561
                     /locus_tag="ACZPB4_06870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YecH family metal-binding protein"
                     /protein_id="HIR1097976.1"
                     /translation="MEQLHAHEVLHMMEGNSYSEASLKEAIVKTFGEDQRFYTCSAEN
                     MDADELIVFLKQKGKFMPVENGFTVDITKVCNH"
     gene            8011..8361
                     /locus_tag="ACZPB4_06875"
     CDS             8011..8361
                     /locus_tag="ACZPB4_06875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HIR1097977.1"
                     /translation="MLTGFLNTLATIISVTSLLIVTYGALIGVISFFRNELKRLTGNY
                     SITNIRKLRAVFGTYLLLGLEFLIASDILKTVLEPTLNELAILGGIVVLRTVLSVFLN
                     KEIKELDTENKDTE"
     gene            complement(8718..8939)
                     /locus_tag="ACZPB4_06880"
     CDS             complement(8718..8939)
                     /locus_tag="ACZPB4_06880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIR1097978.1"
                     /translation="MPIIVNLDVMMAKRKISLNELSERVGLTLSNLSILKTGKAKAIR
                     FSTLEAICRALDCQPSDILEYVNDEKKTT"
     gene            complement(8942..9421)
                     /locus_tag="ACZPB4_06885"
     CDS             complement(8942..9421)
                     /locus_tag="ACZPB4_06885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HIR1097979.1"
                     /translation="MKRISTAFLQTVIVLIGIVALIILIWFPLTEGRATHLDLFSTYA
                     DPFILYGYGASMAFFVALYNAFRLLGYIGQNKVFSTNSVKTLKNIKHCAILLSILIVV
                     AGLFIRLTHNTEDDPAGFLAICMATTFVAIVVATAVAVFEKLLQNAIDMKSENDLTV"
     gene            complement(9712..10020)
                     /locus_tag="ACZPB4_06890"
     CDS             complement(9712..10020)
                     /locus_tag="ACZPB4_06890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097980.1"
                     /translation="MKKVLVAVVLMMGIGSFSAFAAEISVDSVVIACEVNQDDFVKVE
                     VKDLPGVVTQSIEKSYPDSVIQEVYVAEKTEGKLFKVILLIEGKEAIAIFNEKGEEMK
                     "
     gene            10702..10839
                     /locus_tag="ACZPB4_06895"
     CDS             10702..10839
                     /locus_tag="ACZPB4_06895"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097981.1"
                     /translation="MRNTFLTVPIVSALELTLNESASDAMVGGAVTQNDKFQVKHGDY
                     S"
     gene            10942..14178
                     /locus_tag="ACZPB4_06900"
     CDS             10942..14178
                     /locus_tag="ACZPB4_06900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HIR1097982.1"
                     /translation="MERIVNHPILTIPQEGEHTFLFNGKPVTGMKGFTIAAALHQAGY
                     PVHSHSVNGRNRSLNCGIGKCGACEMLVDGEVKRICITKVDNVKEVSEITVQNYTTDS
                     QIEPREEPVEIYRTDVAIIGAGPAGLACRETLKELGLNSIVIDSNDKIGGQFLMQTHA
                     FFFFEKERRFGGMRGFDIAKTLAGDDHSGIFLHSTVWDILQNKRIAVKDMLNHKNFYV
                     EAQALIVATGAVPFMPTFENDDVPGVYTAAVVQKMMNAEFTLLGKNILTVGAGNIGYL
                     TSYQLMQAGAKVKAILEAMPHEGGFPVQANRIRRLGIPIYTSHMLLKAIPDLDRTGIT
                     GAVVCECENFKPIPGTEKVIDGIDVINICTGLIPDNQLLTKGQYTFGKRCAGVGDAVR
                     IGEGTTAVLRGKQAAYEIAQELGVRFNYNDYLQISKEYIDSQQHPIRIKEESPRPTPE
                     RQAQRPFVRLDCLYGFACNPCSFACPQKAITKSSTSVTPEINYEKCTGCMQCVSHCPG
                     LAIFGYDTRKQNLFLPVEYEVEVGAEVWLVDDNGKKQGEGIIEKVLKMPTKTNVARVK
                     AAGMENDALLNITGFIVKENYPEEIDFKQEPECESETYVCHCEDVSLDELLSAIGDRK
                     YISVDEVKHITRLGMGPCRGKRCIPRLRMKLREKGIELVGDATPRAPLSTRFVLGEMY
                     PQRQIADTYKVDSGKQVRKTEVLIAGGGIGGSALFRYFAEAGKKTVLINADRGSSWRN
                     IGGGRPAFSIPELAEIACNNQTIFEETQKEYDIHYREIRYITFAHNEATYNDLERSCG
                     WSNAYLIDKKDFQKEVSPYFNTNQNTYFAAQISQHCWQATPGRVIDFIRNKGKERQGE
                     VWEDTHLVEVHKNGRKYHVLLYTHDKRYIEYECDHFVNALGYSAERFARMLGLYTGLY
                     PVKHQALITHRLPNLGKNGDILDMLIDRRKRNDFSAVYGQQFAETGQIIACASPAVDA
                     KAEISNFDELKFNTRRFMEIISEVFCDWIPSLATVPVQATWSGYYVEPRYIIDPDNGL
                     FVGLQGHGFMLAQYLAKLYVDKALGRTVPDYMERLRLDGDGISEKAFK"
     gene            14284..15327
                     /locus_tag="ACZPB4_06905"
     CDS             14284..15327
                     /locus_tag="ACZPB4_06905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009009 - site-specific recombinase
                     activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HIR1097983.1"
                     /translation="MNIETTDNSPLLQECIEELINSKIDEGKGRTAGNYRSAWNKLST
                     FLGPRVTEFTFADLTTDFLHHYLLWLMQGEDGKQAPLKPGSLDFYIRNLKTMYNKIAQ
                     DKQMDVPRESPFSGLQIKVPPTRKRALPSLDLQNLATLERPKNPHACTALHLTLFLFY
                     ARGMCFVDVFNLRHSNINDDYIHYVRSKTGVAMQVKITPEIKNIIFSYRRFNNPWIFP
                     FLHEKISGEGEVTAQSALRRVNRHLKKMGEQLHFEQPFTTYVMRHSWASMMLEANSEI
                     GIISQSLGHMSLRTTEIYLGRISVSKIDRASDNMLNNLVRSSSTRQRSKNKVMALRDN
                     RQEMQEAHFLDCL"
     gene            complement(15416..15580)
                     /locus_tag="ACZPB4_06910"
     CDS             complement(15416..15580)
                     /locus_tag="ACZPB4_06910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010183089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-crystallin domain-containing protein"
                     /protein_id="HIR1097984.1"
                     /translation="MTDYNIYQDYHYKLTVNIAGPNSADLRVTITNGNVAVFDDVDNV
                     ENTVNFGEEK"
     gene            complement(15983..16885)
                     /locus_tag="ACZPB4_06915"
     CDS             complement(15983..16885)
                     /locus_tag="ACZPB4_06915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIR1097985.1"
                     /translation="MNEIKRIDTVQQYNDYFGMETLHPLVTVIDAREANPVHFCPKLY
                     NLYAILMKDPDCGTLKYGRSIYDYQQGTMLFLAPGQVMGSDDDGQLHQPGGWLLAFHP
                     ELVRNTPLAQFIKNYSFFSYSANEALHLSEQERRTIIDCMCKIREELLHPIDKHTKSL
                     ITDNIKLLLDYCERFYDRQFETRENVNLDILARFEQTLDDYLASNLPISKGTPTVQYC
                     ADKLCLSANYLSDLLKKETGVSALKHIQQKMLDIAKERVFDVTKSISEISYELGFPYP
                     QHFSRWFKKMVGVTPNEYRQNRNN"
     gene            17127..17270
                     /locus_tag="ACZPB4_06920"
     CDS             17127..17270
                     /locus_tag="ACZPB4_06920"
                     /inference="COORDINATES: protein motif:HMM:NF020119.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008239 - dipeptidyl-peptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CocE/NonD family hydrolase C-terminal
                     non-catalytic domain-containing protein"
                     /protein_id="HIR1097986.1"
                     /translation="MAVPGPFDQTEIEKREDVLVYTTPVLHTAVEVTGMVELKLYVSF
                     KQL"
     gene            complement(17374..18387)
                     /locus_tag="ACZPB4_06925"
     CDS             complement(17374..18387)
                     /locus_tag="ACZPB4_06925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1097987.1"
                     /translation="MKQDTIHINGLSIGYHSKSSTKLVAKGIHSTIYSGELTCLLGAN
                     GVGKSTLLRTLSAFQPKLDGEILVLGKDIDAYSDKELSTTIGVVLTDKCEIRNMLVRE
                     LVGMGRSPYTGFWGKLSKDDKRIVEESIALVRIEELASRMVHTLSDGERQKVMIAKAL
                     AQETPVIYLDEPTAFLDFPSKVEIMQLLHHLTRKTNKTIFMSTHDLELALQISDKIWL
                     MDKANGISTGTPEDLALSGHLSNFFARKGIVFDKDTGLFRIDNQFSRQIRLVGHGQKY
                     AMVRKALQRNGILANREVESNIWIETGDLKTTHFIIHETSGGTYITQTIEELLAYFDT
                     EKS"
     gene            complement(18389..19426)
                     /locus_tag="ACZPB4_06930"
     CDS             complement(18389..19426)
                     /locus_tag="ACZPB4_06930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008157907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HIR1097988.1"
                     /translation="MRHSNTLWMLAIVTAIFVLIFLNLVLGSVSIPLQSVWHIIWNLG
                     NEPITWQNIIWKSRLPQALTALVAGAGLSISGLQMQTVFRNPLAGPSVLGISSGASMG
                     VAFVVLLSGSLGGVALSKLGFMGEIALSIAAVIGSLSVMALIVYVSQKVKGNVTLLII
                     GVMIGYVANAVIGVLKFFSVEEDIRAYVIWGLGSFARVSGNQMTLFVILMTILIPLSF
                     LLIKTMNLMLLGDSYARNLGLNIKRARLLVITSAGVLTAIVTAYCGPIIFLGLAVPHL
                     CRAIFQTSDHRILMPAVLFAGAALALICNLIARMPGFEGALPVNSVTALVGAPVVASV
                     LFRKRKNELNE"
     gene            complement(19436..20599)
                     /locus_tag="ACZPB4_06935"
     CDS             complement(19436..20599)
                     /locus_tag="ACZPB4_06935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HIR1097989.1"
                     /translation="MNKFIAGGCLLLSVLTLSCTSGIREKGEIGKTASVEQSAFSQEQ
                     VKPLYAQGFKLTYADQYLLADIQDPQNEESTTFHYAFVKRGAKPTGIPADYTVIELPI
                     RSVICMTSLQLSNFIKLGALDRVVGITSTRHLFNKEMNERLKEGKTAKIGIEGNFDNE
                     VIMSMNPDLILVSPFKRGGYETLKDVGIPLIPHLGYKETTPLGQAEWIKFVGLLLGIE
                     KDGNERFATIEKRYNELKELTADGKVKKRPIVFSGELRGGNWYAVGGKSFLAQLFKDA
                     GADYFLKDDEQSGGVTLDFETVYNQADDADYWRIVNSFPGTFSYEALKEQDPRYEDFR
                     AFREKGIIYCNMKNTPFYESMPTEPEIVLADLLHIFHPDLLPDHESVYYSRLK"
     regulatory      complement(20663..20861)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            20928..21632
                     /locus_tag="ACZPB4_06940"
     CDS             20928..21632
                     /locus_tag="ACZPB4_06940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-2 C(20)-methyltransferase"
                     /protein_id="HIR1097990.1"
                     /translation="MNHPIHFVSLGPGDPELITLKGLKTLQKADIIYCPATQGKHGII
                     SRATDILKAIEVDESLIHPFILPMSKERTDALNAYNKLFLDAQAEYLKGKQIVIVAEG
                     DAGFYSSIQYVYDKFEETGIPVDRIAGIPAFIAAGALAGIHIVKQEEQINVIPGTASF
                     DELSAKIENGMIIVIMKLPGCQEAIHTCIRQYADKAVFHYFENVGTRKEYYTTDIATI
                     HSKDFPYFSLLIIQPR"
     gene            complement(21681..22193)
                     /locus_tag="ACZPB4_06945"
     CDS             complement(21681..22193)
                     /locus_tag="ACZPB4_06945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HIR1097991.1"
                     /translation="MSTVRFSQVTFATKSWVAEAWEKMVVELFSGRVVAEVKQLDEVC
                     ESKWEVELKKLQNEVHSLCHHAIHQLLPIAGSYQQALLDDVAQAYTVYAPEEAESIFN
                     RGNQAIEDIKGHVSGIRYNACKMREANRKVSELEDMHAKAVMYHNSVKPYMDTLRFHI
                     DQLKHILHVA"
     gene            22587..24254
                     /locus_tag="ACZPB4_06950"
     CDS             22587..24254
                     /locus_tag="ACZPB4_06950"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008022575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004329 - formate-tetrahydrofolate ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HIR1097992.1"
                     /translation="MKSDIEIARETDLRKIKEVATTLGIPREEVQNYGRYIAKVPIHL
                     IDKKQMDQHNLILVTAITPTKAGIGKTTVSIGLALGLNKIGKKAVVALREPSLGPCFG
                     MKGGAAGGGYAQVLPMENINLHFTGDFHAVTSAHNMITALLDNYIYQTRNTCEGLKEI
                     KWKRVLDVNDRSLRNIVSGLGGSANGVPTETGFDITPASEIMAILCLATDIEDLKRRV
                     GNILLGYTNEDKPFTVNDLGIAGAITVLLKDALLPNLVQTTENTPAFVHGGPFANIAH
                     GCNSISATQMALTYGDYVITEAGFGADLGAEKFFNIKCRKAGLSPKLTVIVATAQSLK
                     LHGGVPEKEIKEPNIEGLKNGFANLDKHIENMKSFGQQVIVTFNRFATDTDEEIALVA
                     EHCEEKGVGFAMNNVFAEGGEGGTELARLVVDTIENHPSAPLQYTYDLNDPIRTKVQK
                     VAQKIYGASSIVYTTLADKKLRQIESLGISHYPICIAKTQYSFSSDPKAYGVAKDFEL
                     KVRDVIINNGAEMIVVVMGEIMRMPGLPKEPQARKIDIVDGMIEGLS"
     gene            complement(24362..25246)
                     /locus_tag="ACZPB4_06955"
     CDS             complement(24362..25246)
                     /locus_tag="ACZPB4_06955"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097993.1"
                     /translation="MKRVLFTLVACLVGISSLMAQSFSLPGYLFGRCPDYSITYDKND
                     AQEQKDVYICDGNKSVVRIDSYKWNSSSSDWVYDGKTVMENDNQGRTLVAISYSAADV
                     AGEKTEYTYTGNGYEKFSVTSSSFEGGAWKAEAKVDIEATFNKDKYPVSILMTGTAEG
                     ETFKMKMEWSYDKNVTKTSSSIDFGGSWMLMSESKTEIVDAGNPMISKNYQKMYFPAE
                     TSWEYSGKTHDYFNGTTSIAPVVEENELKLHIYGDVLEVQGTESGISIYAITGGKMAE
                     SKSNRIDTSLACQQESIC"
     gene            complement(25278..26333)
                     /locus_tag="ACZPB4_06960"
     CDS             complement(25278..26333)
                     /locus_tag="ACZPB4_06960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HIR1097994.1"
                     /translation="MTAKEIFFKTLQFGWIKLGLGLLNILIAVLLFAILMGISVLFNS
                     DGVVAIMFFIWLGLIGVVNFFLNHYIGYLVKAGHVAVIAMAYQTGYVPAKPFEMGKTM
                     VKERFGTSNVYFALDKLVAGSIKQLQRTLGRVTDSLLGALPGADGIKSLTNMFLDISL
                     GYVDECCLGYTFYHPAQNPYKSAADGVIIYFQNWKTLLKDAAKTTGMVILSFVVVTLI
                     AFILFGGLFRLFGWSGFMAFIISLLFAYTVKYAFIDSWILVKMMSSYMQVAPATQVTF
                     DLYGKLSGLSGKFKELFKKGNEMPQPNPTATSAAQDPLRPQIPGQVSTPESRFCPQCG
                     MQLAPTATFCGNCGERL"
     gene            complement(26360..26947)
                     /locus_tag="ACZPB4_06965"
     CDS             complement(26360..26947)
                     /locus_tag="ACZPB4_06965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4870 domain-containing protein"
                     /protein_id="HIR1097995.1"
                     /translation="MAFCGKCGQQVNEGVRFCPACGSPMQIVAAEPNRQQTPPPVQPT
                     DAESMAKATATADALSDKLSGMNKTADLTDQFDKADVEQNKVMAILAYFGILVLIPIL
                     AAKDSKFARFHANQGLLLCIAMFGWIIADSVLTALLRAILWRGLGLWSIYSLCGTVLN
                     LVYIVFTVLAVIGIINALNGRAKELPIIGKYRLLK"
     gene            complement(26979..27494)
                     /locus_tag="ACZPB4_06970"
     CDS             complement(26979..27494)
                     /locus_tag="ACZPB4_06970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="HIR1097996.1"
                     /translation="MAFCTNCGTNVPDGIKFCTSCGTPMSVQAQPQAPPPPQQTYVQP
                     QPAPQPLPQQAYAPPSQPAYAQPQPGYVAPAGDPNAPLPPGSKYEPITTGGYIGIFLL
                     MLLPLINLILLIIWACGGCQKVNKANFARAMLIMMIIGSVLSLLMFFAVRMLFGSEID
                     SLMEAFGDLLK"
     gene            complement(27528..27803)
                     /locus_tag="ACZPB4_06975"
     CDS             complement(27528..27803)
                     /locus_tag="ACZPB4_06975"
                     /inference="COORDINATES: protein motif:HMM:NF024183.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="HIR1097997.1"
                     /translation="MYSQPTSRRRKAALERAEAEERARREAEEQEHSCPNCGAYNPEG
                     TNFCQECGTRLTQPVQQAPAAKRFCPNCGTEVIAGHRFCSGCGTKME"
     gene            complement(27706..28002)
                     /locus_tag="ACZPB4_06980"
     CDS             complement(27706..28002)
                     /locus_tag="ACZPB4_06980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097998.1"
                     /translation="MGDILTGIVKGLSGFMLQDDPDVKIFNAQTEMKEFSEREGKIYA
                     RLGRQVYETDGGENYPEIRAELDLLAANKQAAESRPRTCRGRGTCPPGSRGAGA"
     gene            complement(28009..28359)
                     /locus_tag="ACZPB4_06985"
     CDS             complement(28009..28359)
                     /locus_tag="ACZPB4_06985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1097999.1"
                     /translation="MKQTLFTFMFIISLVLMTACGGSPVDKALAKLDDAIEKLEKKGD
                     KMTKDEMDAIMKDLEEPVSVLNKTIEDNEVGGVTKIKIIAKVTKLTALATKVGIKNLD
                     MGDFSDKAKGTKKE"
     gene            complement(28381..29058)
                     /locus_tag="ACZPB4_06990"
     CDS             complement(28381..29058)
                     /locus_tag="ACZPB4_06990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TapB family protein"
                     /protein_id="HIR1098000.1"
                     /translation="MKTNIRFLVMIAVSLLTVLGMSAQEPFFLHKEGVKLTYADKDKK
                     GKINSYTETTATKVTGDADNCTVTYSMMVMDNKKNPVLKQPMTQTFEVKNGTVTYDPK
                     SLVGQIMEGMQVTVTGTPFQLPSNVKVGDTFGDYTITLNLAGIKTNTEVTGVKAVAEE
                     TLDVNGTSIDCVVIENTTVSKVIGIKQTAIQKIWYGHGIGPVKTNMYNKKGKLMTSQE
                     LVSIEGL"
     gene            complement(29092..29817)
                     /locus_tag="ACZPB4_06995"
     CDS             complement(29092..29817)
                     /locus_tag="ACZPB4_06995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4412 domain-containing protein"
                     /protein_id="HIR1098001.1"
                     /translation="MKRLILLLICALYVTTAAQAQISFYGEWCRKGSGEKTIMIFDMK
                     EKKAYVMNEARKTCMVMEEIDKLSTNKLVGYDWEVSHSTSREFLGMEEIDGKECAHYY
                     VKSESIYKDGGKDGAGYHEWIYSPMKVSNYNGCIAHDNTVYVMDRTIVLRRVKMGPQP
                     AHLFQVPEGYQMTVMPAGGLLEMMTGKSCEENTQKVDETRDAIQKSNEQIKEQLKEVN
                     DKSKSDEERMKALLEMLGGQKKK"
     gene            complement(29838..30335)
                     /locus_tag="ACZPB4_07000"
     CDS             complement(29838..30335)
                     /locus_tag="ACZPB4_07000"
                     /EC_number="2.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0071972 - peptidoglycan L,D-transpeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0018104 - peptidoglycan-protein
                     cross-linking [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HIR1098002.1"
                     /translation="MATLRAQEEKADGTNRVIVSKQDMRITVLCPQGDTLAVFPIACG
                     RNYGDKQQEWDFRTPEGHFVIESVEDTSLWPRDSTRQETPGEIYGPRFFRLKTPGFTG
                     IGIHGTANPQVIPGRITMGCIRLSNEDLKAFSRLVDVDTRVDILPDKGRERGSLSKLA
                     RDDDY"
     gene            complement(30426..30911)
                     /locus_tag="ACZPB4_07005"
     CDS             complement(30426..30911)
                     /locus_tag="ACZPB4_07005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HIR1098003.1"
                     /translation="MAKYKLIKKVNPQKRQEPGKWYATPKSETPLSGKAMTCAATANT
                     TTAPIEMEASLELLAKFVPQQLQQGHTVKIPGLGTFRLTFKSDGVEDINSFRANSMIK
                     NVRIVFTPSKELRESVLSGLTFEDGGVLEDDISYASIADYRLAKGVPEGGGDSESPGE
                     I"
     gene            complement(31149..31316)
                     /locus_tag="ACZPB4_07010"
     CDS             complement(31149..31316)
                     /locus_tag="ACZPB4_07010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098004.1"
                     /translation="MANYGKYGFLPSIALCLLWATEVSWAQVKLVRMPVVEKSGSISS
                     GKSIIRLWRIN"
     gene            complement(31530..32087)
                     /locus_tag="ACZPB4_07015"
     CDS             complement(31530..32087)
                     /locus_tag="ACZPB4_07015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098005.1"
                     /translation="MIFPEFGIRTELAVAVVFPELVRYSALMDFMETTAVKALYQQKG
                     VKGADFSIGRFQMKPSFVEDLERQWMRTEWRHEYGIYFDLSETLEAHRICVLRLDDRN
                     WQCIYLAMFLKLLYRRFPELAEEEDIEQVRFCSTAYNASFYGTYECIRSKSARRFYHT
                     DFIPTPGTKRYAYSEIAVFYYKIAL"
     gene            complement(32222..33811)
                     /locus_tag="ACZPB4_07020"
     CDS             complement(32222..33811)
                     /locus_tag="ACZPB4_07020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098006.1"
                     /translation="MRKILNIMAIALAIFCRIPVEVHGQSFLKKLKQKVGNVVGTKDD
                     TAEIGEEPFVGGDGDQPTRSVTPTDKLQKRRTATATWDEMIAPSRANSPEALLNELPP
                     LPSVESIVYPEETARATYYRKIVAVDMRITELDSIHTCSDEEMIALRDKFYVELADIN
                     GITVEEMKSLEDPNLPEAEKERLIEKMKNALVGDTRGLEAMGANLEKREAAKGGKLTN
                     EEKMAFLAENQGNLSDLGSMMEKMQATNEKTTAFNAKFVKLEQMTVQQTEKMKKILQA
                     SDGAITSCEKIAGEYESELKTLYAQIYETDDSQKVEELYARADERMKNYRLRAAKLWR
                     NSLQTQLDGVKAMYPDIVKLQKEMMQEGIIPTCAEKRASFNAVTNYTNILHKAYRDFP
                     QPRVLPVYMETIIEIPEGEHLFYAESGFATSVDGFLNNSRVYTADNAGKRYLYENGKK
                     RELGPNDPGDFQAKGARTEPTYGAWTSASGTRKVTYTRDGSLTLHDGTSFYPLAFKKE
                     SDRLVWIIASSAGVEKCTYKL"
     gene            complement(33847..34467)
                     /locus_tag="ACZPB4_07025"
     CDS             complement(33847..34467)
                     /locus_tag="ACZPB4_07025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098007.1"
                     /translation="MQNWDAHYFVDKELLRFGQTTIVGDAPMFASDIRINQSYMKLWA
                     ESWGLGFKHSTKPTQAHNIYRLPVKVVVNMPKKPTKSVYASTEVFMGDREWMPGDKPQ
                     PEIETYFQLQHNVAVSGTVSDEGISFKADHYLNYYATRDFIVIDGNINDGLSISGLGT
                     IPFRSQGSVNDPIPKEGFGGKPDGSIQIHIDQSLDDVEKWERIRYE"
     gene            complement(34433..>34938)
                     /locus_tag="ACZPB4_07030"
     CDS             complement(34433..>34938)
                     /locus_tag="ACZPB4_07030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098008.1"
                     /translation="ISGVKDRDKYYEAERIQGRLKSEAYKYLVNKTLSTVGKIFSLKG
                     RVEIFLNARERDKQKWINCVAEDNLVSLARFYRIANNRLWQIAQTKGQTWVLRVNGSA
                     NAPFFYEGEMCVQQWKIKMELEKSYHGANEKLTEQQFYRTFAGEYIGWLDAEVLYAEL
                     GCALFCG"
BASE COUNT         9443 a         8358 c         7456 g         9681 t
ORIGIN      
        1 tagagggtag attgatcact caatccaccc tcctgtctac cgtgtgctta aactattaaa
       61 aatcaacccc ttgattagtc ttctagagcc gcttgcgccg ctgcgatacg agctatgggc
      121 actctaaaag gtgaacatga tacgtaattc aagccaactt tatggcagaa cttaacggaa
      181 gaaggctcac caccatgctc gccgcaaata ccacatttca aatccggacg gatggcacga
      241 cctttctcag ttgccatacg aaccagctgt cctacaccat tttggtctag tacttggaac
      301 ggatcgacct tcaaaatctt cttctctaag taaaccggta agaaggaagc gatatcgtca
      361 cgagagtaac caaatgtcat ctgagtcaaa tcattcgttc cgaatgagaa gaattcggcg
      421 ctggaagcga tacgatccgc tgtcaatgcc gcacgaggaa tctcgatcat cgtacctacc
      481 ttgaattcga tacgatcgcc aacttccttg aatagctctt cggccgcggt acggatcacc
      541 ttctcttgtt ccttgaattc atataagatt cctgttaatg gtaccatgat ttccggttta
      601 gcctcaatac cttctttctt caaatccaaa gcggcaccta aaatggcccg agtctgcatt
      661 tccgtaattt ccggatatgt attacctaga cggcaaccac ggtgacccaa catcgggtta
      721 tgctcgcaaa gagattccac acgtttttgg atctccttaa cggacacgcc cattgtctca
      781 gccatttcct cttgaccttt caaatcgtga ggaacgaact catgcaaagg aggatcgagc
      841 aaacgaacgg taacaggaca tccggccata gccttgaaga tacccttaaa gtcctctttc
      901 tgataaggaa ggatcttcgc caacgctttc ttacgacctt cagcgtcctc ggccaagatc
      961 atctcacgca tagctttgat cttctcacct tcgaagaaca tatgctccgt acggcaaagg
     1021 ccaataccaa cggcaccgaa gctacgagcg atcgaagcgt cgtgaggcgt atcagcgttt
     1081 gtacgaactt gtaattttgt atatttatcg gctaaagcca ttagctccgc gaagtcacct
     1141 gacaactctg ccgctttcgt ctcgacctgt cctacataga cttccccggt cgtaccattg
     1201 atagagatat aatcaccttc tttcaaagtc acgccatcaa cgtctacagt cttattctta
     1261 taatcgatgt tcaaggcacc agcaccggat acgcagcact tccccatacc acgagctaca
     1321 acagcggcat gagatgtcat acctccacga gcggtaagga taccttcggc gacagccata
     1381 ccggccaagt cttccggaga agtctcaata cggaccatga caaccttttt gccatcggca
     1441 tgccatttag cggcatcatc agcaaagaat acgatctgtc cggtagcggc acccggtgaa
     1501 gccggcaaac cttttaccca cactttcgcc agtttctcgg cttttttatc gaatacaggg
     1561 tgaagcaact catctaattt attcggctcg atacggttca acgctgtttt ctcatcgatc
     1621 ataccttgat gcaataagtc gatagcgatt ttcaccatag cggcaccggt acgtttgccg
     1681 ttacgggttt gcaagaacca aagtttaccc tcttgtacgg taaattccat atcttgcata
     1741 tcccgataat gatcttccaa tttctcttgg atagcgtcta attgcttata gatttccggc
     1801 atggcttctt ccatggacgg atatttagcg atacgttctt cttctgagat tccggcacgt
     1861 tcagcccaac gttgtgaacc gatcttcgtg atctgttgcg gggtacggat acctgctaca
     1921 acatcctcac cttgagcgtt aatcaagtac tcaccattaa acaagtcctc accattaccc
     1981 gcgtcacgag agaaacaaac gcctgtagcg gaagtatcgc ccatattacc gaataccatg
     2041 gcttgtacgc taaccgccgt tccccactcg tctggaatac cttccatctt acgatacagg
     2101 atagcacgct cattcatcca gctattgaac acggcacaga tagcgcccca caattgctca
     2161 taagcgcaag tcgggaaatc ctgtccggtc tgggccttaa cggctgcctt aaatttagag
     2221 accaatgttt tcaagtcttc aacgtcaagc tcgttatcta acttaacgcc tttcgctttc
     2281 tttacttcct cgatgatcgc ctcaaacgga tcaatatcct ctttgcttgt cggtttcata
     2341 cctaatacga catctccgta catttgaacg aaacgacggt aggagtccca agcgaaacga
     2401 gcgttgcccg tcttacgaga caatccttcc actacctcgt cgttcaagcc aaggttcaat
     2461 atcgtatcca tcatacccgg catggacgca cgggcaccgg agcgaactga aactaacaga
     2521 ggattggcaa catcaccgaa cttagagttc attaacgttt cgatattagc gatcgccttc
     2581 tcaacatccg ctttcagcaa ctctacgact ttatctttgc ctaactcgta atactctata
     2641 caaacttctg ttgtaatcgt gaatcccgga ggaaccggta caccaatcag attcatctcg
     2701 gcaaggttag cgcctttacc acccagcaga tttctcatat ctgccttacc ttcggctttt
     2761 ccatttccga acgtgtaaac tctttttctt tccatattcg acagtattga atttagattc
     2821 tagttttgtt gatttcaact gttatattgc tatctcaact ttgcaatgct gcaaatatat
     2881 gctatttcta ctttgcaagc acgaatagcg ttaaagattt ttacatgttt tacaactatt
     2941 ctttaccatt tatatccagc aaatgcttac atttgcgtgc ggaagtttgt tgacgcttcc
     3001 atttcccttc ggatttcccg cctatctctt tgccccttac atataattat atgatctttt
     3061 tcttttattt gtgtctattt atttccaata ggaagactca ggagtttttt gctgaagaaa
     3121 ctttagtttc tacagcatga aactaaagtt tctccctagt ggaactaaag tttttctata
     3181 gcaaaacaaa agttttcctt ataagaaatt ttaagaaact gcaatatgtt gatttataaa
     3241 cacatactat acatcccttt ctgtccataa tcatatcttc atcaatcttg atagaataac
     3301 gagaactgtt tgccggactc atttaagtat atagaacgaa gctctttgtt cttagcggaa
     3361 ttgtaagtat tttcgcgaag cgaatttaaa acttaacgac attggcaaga aagaagaaac
     3421 agttgcctat attagaaaag gtaaccatta cggacgtagc cgccgagggc aaggctatcg
     3481 cgagagtgaa cgatatggtg gtatttgtac ccttcgtcgc tccgggagac gtggttgata
     3541 ttcaactgac ccgtaagaag aatagttatg cggaggggaa acctgtatat ttccatgagt
     3601 actcggccaa acgtgcggag ccgttttgtg agcacttcgg tgtctgtgga ggttgcaagt
     3661 ggcaacatct tccctatgag gaacaacttt actataagca aaaacaggtc tacgataatc
     3721 ttacccgcat cgggaaagtc gaaatggaag agaaacttcc gatcttaggt tccgagcgca
     3781 cgactttcta ccggaacaag cttgagttta ctttctcaaa caagaaatgg cttacggagg
     3841 aagagatcca gtccggtgct tctttcgatt gcatgaatgg tgtcgggttt catataccgg
     3901 ggatgttcga taaggtattg gacatccata aatgttggtt gcaagatgat atatcgaaca
     3961 agatccgtct ttgcgtcaag gaatattgcc tatctcatga gggatatcct ttcttcgatt
     4021 tacggaacca agagggattc gttcgtacgt tgatgatccg tacggcatcc actggggatt
     4081 tgatggtcgt attggttttc ttccatgagg atgtagagcg cagggaggcg ctactatctc
     4141 atctggcgga acgattcccg gaaatcacgt ccttgatgta cgtcatcaac ggcaaatgta
     4201 atgacacgat caccgaccaa gaagttctcg tattcaaggg aaaagaccat atcatcgagg
     4261 agatggaggg gcttcaattc aaggtaggtc ctaagtcttt ctatcagaca aacagtgaac
     4321 aggcttataa tctatataaa gtggctagag aatttgcggg tcttaccgga aatgagatgg
     4381 tgtacgattt atataccggg acaggtacga tcgcaaattt cgtctctcgc caagcaaaga
     4441 aggttatcgg catcgaatac gtaccggagg ctatcgagga cgcaaaagtg aattccgcct
     4501 tgaaccatat agagaacacg cttttttatg ccggtgatat gaaagatatc cttacgcagg
     4561 atttcataaa ccaacacgga cgtccggatg ttattattac cgatccacca cgtgccggta
     4621 tgcatgatga tgtgatcaac actattctct tcgccgagcc ggaacgtatc gtttacgtta
     4681 gctgcaatcc tgctacgcaa gcccgcgatt tgagtttgtt gagcgtgaaa tactccgtca
     4741 agaaagtccg tccggtcgat atgtttcctc atacacatca tgtggagaac gtggttttgc
     4801 ttgagaaaaa ataaacatat aatataatgt ataggaaata cgtccccttt ctgctctttt
     4861 tgttcttctt gtatggttgc aacggtaaca aacaagagga gaaagaggac gtttccgttt
     4921 tcgtggattt accgcaactg aaagcggaag gcgagatcac ggcggtgact ttatacagtt
     4981 ctacctccta cttccaatat aagatgcaac ccatgggtta cgaatacgat ctgataaacg
     5041 attttgtcaa gagccaaggt ttgaaattaa acatcaaggt cgccgagaat cctgcccgcc
     5101 tgatcgagat gcttgaagcc ggtgaggccg atgttgtagc ctaccctatc ccaatcaata
     5161 acaagctgaa acaagaggtc atttattgcg gccgggagga tatctccagt caagtattga
     5221 tacaacgggc caataaaggc gataagcttc ttaccgatgt cactcaatta atcgataaga
     5281 atgtttacgt aaagcctaac accaaatact ccgaacgact gaagaacttg gatgaggaac
     5341 tcggcggagg aatccatatc caaaaagtgg aaaatgactc cattgctacc gaagatctta
     5401 tcgagatggt ctccttgggc gaaattccct atacgatcag cgatgataac accgcccgcc
     5461 taaacaagac ttattattgg aatatcaatg tcgacctaaa ggttagtttt ccccaacgtt
     5521 cttcatgggt ggtaaggaaa agtagtccgg acttggcgaa ggccatcgat gaatgggctt
     5581 ctgataaaac gggtaaacat tctttcaagg cagttactaa gcggtacttt gaattaagca
     5641 agcgaccttt taccgcagat attccggagg taaagaatgg acatatttcc ccgtatgacc
     5701 ctttattcaa gaaacatgcg aaaaacatcg gatgggattg gcagctgctg gcgtctattt
     5761 cctatcaaga gtctcatttc aatcctacgg ttgtatcgtg ggccggtgcc gaggggctta
     5821 tgggaatcat gccaaatacg gcgaaggcat taggtgtcac cccgcatgaa ttgaaagatc
     5881 cggatacggg aatccgtacg ggagtagatt gtttacggcg cttccgtcaa ggtttttctg
     5941 agattacgga tcctgaagaa aaagtcaagt ttaccctagc ggcttacaac gctgggatcg
     6001 gacatattta cgatgcgcag cgattggccc gaaaatatgg aaaagatccc aataaatggg
     6061 ataataatgt agcggaatat attcgtttga aaaatgatcc cgagtattat aacgatcctg
     6121 tttgcaagca tggatacttg cgtggctcag aaacatataa ttacgtgcgg gaagtgttgg
     6181 agcgttatca ttactacaag aaaaagtcat agttataaaa aaattcatag ctatgagtga
     6241 aagtagtcat aactatgaat tttctgcaag taaatgccac ttaaaaatta taggcgacac
     6301 ctatgcctaa tatttccttg aactggacct tcgccccccg tttctctcca ttatcctcaa
     6361 aagttttcac gtcgttatca tatttaagcg tcgtattgag tgtagcggac aggaatttat
     6421 taatcttcat gcttatcaat acatcccaat tgacatcgat atttccgaat tgatcgctat
     6481 aaggagtgaa aaagtcagct gtagtaatca agttcacgtt ttccatcacg gttaattccg
     6541 cacgagcttt caagtaagct ccccattcca ttctgaagcg atctcccgga tcgaccccga
     6601 aagctcctaa cttggaaagg taatcatcct ccacgaaagt catcttcgtg gaagccggag
     6661 aaagataaac cgaataattg cttttgggac gatattccat acctacggag atattcgaat
     6721 acgccggcgc aaagaagttc gatatataat gtgtcttatc cggataatta tatcctttgg
     6781 caaactgggt gtttaaatct cccatcaacg tataatacca tacattattg gtggaatatc
     6841 ctaattgggt agacagggtt atattatcgg tacttttcct cattccctgc gatttagtct
     6901 ttgataatcc gtaatcgaga gcgagattgg ttacccataa ccagtcaccg cttttatgtg
     6961 ttaatgcccc attcagatac gcatttccgg caacagagtt ctcaccgcca gccgaccaat
     7021 tcgacatcgc cgtttgcgac aagttcaaac ctgtcacacc tttcagtacc catttgcctt
     7081 cctcatatcc tttatcatcc gtttgaccat atgtgattgt cgttaatgcg acaaacaatg
     7141 tcatgaagaa tatacgtttc atattgtgat atattttagt tattaaaaaa taagacgtcc
     7201 tatcatttaa acaggtttga ttaatttttg tttagaaaag cctaaagttg aaagggtgtc
     7261 acatttgtta cacctttata cggataaacc ccttattttt gtatccgata attaagtaat
     7321 ttgatttatg gaacagttac atgcacacga agtccttcat atgatggagg gtaatagtta
     7381 ttcagaagct tctttaaaag aagcgatcgt taagactttt ggtgaggatc agcgtttcta
     7441 tacttgttcg gcggaaaata tggatgcgga tgagttaatc gtatttctga aacaaaaggg
     7501 gaaattcatg cctgtcgaaa atggtttcac ggtagatatt acaaaggttt gtaatcatta
     7561 aagattctac gacactatca atgactctag gctaaattct tttgatttag cctaaagtta
     7621 aaaaagactt tcgattctac tcaatggaca atactattcc tataaataat cgcaaatgat
     7681 ttttacatca attcataatc tttatcagag acataactta gcctacggtt acccgcatga
     7741 tttatcatcc agacaaaaga ctctatatac tttagtatct tatttgaatt atcacttttt
     7801 atacgtgaca aataatccat ttttcctaaa agataattac tcacttcaag aacactcatc
     7861 ttattacaag ttttgtatta tcaggttgtt ttttatccat gattgatcct atacgggtaa
     7921 aagtgtgagt ccgaaaacct accatacctg cgggccttcc aacaaacatt ctataggcct
     7981 tttatgttat ggttataaaa tggtctattt atgcttactg gttttttaaa taccttagcg
     8041 acaataataa gtgtgacaag ccttctgatt gtcacctatg gtgcattaat cggagtcatc
     8101 tcatttttca gaaatgagct taagcgactt actggtaatt attccattac taacataaga
     8161 aaactaagag ctgtattcgg tacatactta cttctcggac tagaattttt gatagcgtca
     8221 gatatcttaa aaacagtatt ggagccaaca cttaatgaat tggccatttt aggtggaata
     8281 gtcgtgctga gaacagttct gtctgtcttt ctgaataaag agatcaagga actagacact
     8341 gaaaataaag ataccgagta gatcccataa agttttcaag ggaaagtaca gaaaaatggc
     8401 gcttaagtct tgcatgaaca ggatttaaac gccatgaagt aaagttagaa aaccaaaccg
     8461 ctcggccttc acaggtgaag cggaagtgga tatattgcct taaactaata ccttatatta
     8521 ttacaaccag attaaaggtc ataatgttta tgcttttgat gaatttcaat agccaaaata
     8581 aaacagaaaa taaaaatccg catccagcgt cactgctaca tgcggatcaa aaataacaaa
     8641 ctcttacaag agttaggcac tacataaagt tgtattatac taataagcag actgaaccgc
     8701 atcaaagtgt tgattcctta tgttgttttt ttctcatcat ttacatattc caaaatgtcg
     8761 cttggctgac agtctaatgc tctacaaatt gcctctaggg tactaaaacg aattgctttc
     8821 gcctttcccg tttttaagat agaaaggtta gataatgtca aaccaactct ttcagaaagt
     8881 tcgttcaaag aaatcttccg ctttgccatc attacatcta agtttacaat aataggcata
     8941 attaaactgt taagtcattc tctgatttca tatctatcgc attttgcaat aatttttcaa
     9001 atacagccac ggctgtcgca actacgatag cgacaaaagt agttgccata caaatggcaa
     9061 gaaaacctgc ggggtcatct tctgtattat gggtcaacct tataaatagt cctgccacca
     9121 cgattaaaat acttagtaag atcgcacaat gctttatgtt ctttaaagtc tttacagagt
     9181 ttgttgaaaa tactttattt tgcccaatat aaccgagcaa cctaaaagca ttgtacaacg
     9241 caacaaaaaa agccattgac gctccatatc catataagat aaatggatca gcgtaagtac
     9301 taaataaatc taggtgtgtg gctcgtccct cagttaaggg aaaccaaatc aaaataataa
     9361 gtgccacaat accgataaga acaataactg tttgaagaaa tgctgttgaa attcttttca
     9421 tgacgtatga tgttaatttt aaacgacgtt gcaaatgtaa taaatattta ttgataaaca
     9481 ataaatgaat accgaaattc aaaaaacagt ctctttctca agctaattaa aaaatctgga
     9541 cttgaatcgc cagtgtagtg tcgaagtaca atgatctccc atttggaagg gagaatggga
     9601 atagaagaaa aaaagaacgc ctacctaaaa agtggtagac gctcattgca tacggttatt
     9661 gggacaaata tagagtttat ttctatcttg gattatccta ttcattaata actacttcat
     9721 ctcttctccc ttttcattaa agatagcgat agcctccttg ccctcgatta gcaaaatcac
     9781 cttaaagagt ttcccttcag tcttttccgc aacatatacc tcttggatca ctgaatccgg
     9841 ataagatttc tctatggatt gcgtaactac tcccggaaga tcctttacct cgaccttaac
     9901 aaagtcatct tgattaacct cacaagcgat taccactgaa tcaacactta tctctgcggc
     9961 aaatgcgctg aaactaccga tacccatcat caatactact gcaactaata cctttttcat
    10021 gactcttgat ttttaattaa acaatctatt catattaacg taatcaatag atatagaaca
    10081 acggatatgc caaatttcgc ctatctacag atagtcatga cacacaacat cttatatttt
    10141 agcattaaca tatgaattgg gatattacgg gattttatgg gacatttttg ggtaattatg
    10201 ccccaaaagt cccaattcat tgccataacc cttgtaaaac atttgtgaaa caaattatct
    10261 gtttttgagc aaacagagtt agacaaaaac gatatattta gccatctaaa ttctattgaa
    10321 agccagattc catgcggaaa caaataaaaa tccgcatcca gcttcacagc tacatgcgga
    10381 ccaaacaaat aacaaactct acttatatga aaaaacaaat actactaaca aattattata
    10441 cgatgactac tatcaaggtg acttctgagt cattttatag tataacagaa gattgtttga
    10501 aaaggttcac cagtaatttc ttttagtctg agagcttttc tttttatcga ctgtttgaat
    10561 ataaaacatt tcaagctgca aattgtttta caaacaaaga taaaaatgat gattgatcgg
    10621 tttgaggcat gattaagaag ttattttcta tattattgtt tatgataatg ctctttgcct
    10681 tccggatgaa tgcggaagcg gatgaggaac acttttctaa cggttcctat cgttagcgca
    10741 ctagaattaa cattaaatga aagcgcttcc gacgctatgg ttggtggagc ggttactcaa
    10801 aacgacaaat ttcaagtaaa acacggcgat tactcctaaa tctttaggga taatcgcttt
    10861 ttcatgaata gatttcaagt aaaattagga catttatcca attatatccg taattttagc
    10921 ccaattaaat caatagcaat tatggaaaga atcgttaatc atcctatttt aacaattcca
    10981 caagagggag aacacacttt tttattcaat ggcaaacccg taacgggaat gaagggtttt
    11041 accatcgccg ccgccttaca tcaggccggc tatccagtac acagtcatag cgtaaatggc
    11101 cgcaatcgtt cgctgaattg cggtatcggt aaatgtggcg cctgcgaaat gctggtagac
    11161 ggagaagtaa agcgtatctg tattacgaaa gtagacaatg taaaggaagt atcggaaata
    11221 acagtacaga attatacgac agattcccaa atagaaccca gagaagaacc ggtagagatc
    11281 tatcgaacag atgtggccat cattggtgcc ggccccgctg gattagcttg tagggaaacc
    11341 ttaaaagaac taggcttgaa cagcatcgta attgatagca atgataagat cggtggtcaa
    11401 ttcttgatgc aaacccatgc atttttcttt ttcgagaaag agcggcgctt tgggggtatg
    11461 cgtggtttcg atatcgcgaa aactttagcc ggagacgacc actctggtat tttcttacat
    11521 tctacggtct gggatatcct acaaaataag cgtatcgccg taaaagacat gcttaaccat
    11581 aaaaatttct atgtagaagc tcaagccttg atagtcgcta ccggtgcggt tccttttatg
    11641 ccgaccttcg agaatgatga tgtgcccgga gtttatacag cggcagtcgt acagaaaatg
    11701 atgaacgctg aattcacgtt actcggcaaa aacatattga cagtaggcgc cggtaatata
    11761 ggttacctaa cgtcctacca attgatgcaa gccggagcga aagtcaaggc tattttagag
    11821 gcgatgcccc atgaaggtgg atttccggta caagcgaatc gaattcgccg ccttggcata
    11881 cctatttata cctctcatat gcttttgaaa gccattccag acctggatcg gacaggtatc
    11941 actggcgcag ttgtctgcga atgcgagaac ttcaagccaa tcccgggaac agagaaagtg
    12001 atcgatggta ttgatgttat taatatatgt acaggattga ttcccgacaa ccaattgcta
    12061 accaaaggcc aatatacatt tggaaaacgt tgtgccggcg taggtgatgc cgtacggatc
    12121 ggagaaggta ctaccgccgt actaagagga aagcaagctg cttatgagat cgcccaagag
    12181 ctaggcgtac gtttcaacta caacgattac ttacaaatat ctaaggaata catcgactcc
    12241 cagcaacatc cgatccgcat caaggaagag tccccaaggc ccactcccga gcgtcaagcc
    12301 caacgccctt tcgttcgctt ggattgccta tacggtttcg cttgtaaccc ttgctctttc
    12361 gcttgtcctc aaaaggcgat caccaaaagc tccaccagcg taacgcccga gatcaattac
    12421 gaaaaatgta ccggctgtat gcaatgcgta tcccattgtc cggggctggc tattttcggc
    12481 tacgataccc ggaagcaaaa cttattctta ccggtagaat acgaggtgga agtaggtgcc
    12541 gaggtgtggc tcgtcgatga taacgggaag aaacaaggcg aaggtatcat tgagaaagta
    12601 ttaaagatgc cgacaaaaac aaacgtggcc cgtgtgaaag cggcaggaat ggaaaacgat
    12661 gccttattga atatcacagg attcatcgta aaagaaaact atccggagga gatcgacttc
    12721 aagcaagaac cggagtgtga gtcggagacc tatgtttgcc attgcgagga cgtatctttg
    12781 gacgagctac tttccgccat tggggatcgt aaatatatct ccgtcgacga ggtaaaacat
    12841 atcacccgcc taggaatggg gccatgccgt ggaaaacgct gcataccccg cctacgcatg
    12901 aaactaaggg aaaaaggtat cgaactggta ggcgacgcta ccccccgtgc tcccctatct
    12961 acccgcttcg tcctagggga aatgtatcca cagcgtcaga tagcggatac ctataaagta
    13021 gattctggaa agcaggttcg taagacggaa gtcttaatcg ccggcggagg tataggtggt
    13081 agcgcattgt tccgttattt tgcggaagcc ggtaaaaaga ccgtgcttat taatgcggat
    13141 cgaggatcat catggcgtaa tatcggtggt ggtcgtccag cgttctcgat ccccgaacta
    13201 gcggagatcg cctgtaataa ccaaacgata ttcgaggaga cacaaaaaga atacgatatc
    13261 cattaccgtg agatacgcta tatcacgttc gcccacaacg aggctaccta caatgatctg
    13321 gaacgttcct gcggttggtc caacgcttat ttgatcgaca agaaagactt ccagaaagag
    13381 gtgtccccct acttcaacac gaaccaaaac acctatttcg ccgcacaaat ctcccagcat
    13441 tgttggcaag ctaccccggg gcgtgtgata gactttatac gaaacaaagg caaagagcgg
    13501 caaggtgagg tttgggaaga cacacaccta gtggaagtac acaaaaacgg tagaaaatat
    13561 cacgtcttat tatatacgca tgataagcga tacatcgaat acgaatgcga tcatttcgtg
    13621 aacgccctcg gttatagcgc cgagcgtttc gcccgcatgc taggccttta caccggcctc
    13681 tatccggtca agcaccaagc gttgattacc catcgcctac cgaatctggg taaaaacggg
    13741 gatatcctcg atatgttgat agaccgccgg aaacgtaacg acttctccgc tgtctacggt
    13801 cagcaattcg ccgagaccgg acagattatc gcttgcgcct cccccgctgt cgacgctaaa
    13861 gcggagatca gcaactttga tgagttgaag tttaataccc gtcgtttcat ggagatcatc
    13921 tccgaggtgt tctgcgattg gattccatcg ttagccacag tacccgtaca agccacatgg
    13981 tccggttatt atgtagagcc tcgctacatt atcgatccgg ataacggact attcgtaggt
    14041 ttgcaaggtc acggcttcat gctcgctcaa tacttggcta aactatacgt agataaagcg
    14101 ttaggccgta ccgttccgga ttatatggag cgattgaggc tcgatggaga cggaattagt
    14161 gagaaagctt tcaaataaac tataaataaa acaaagcctc ctctaccaca attggtaagg
    14221 ggaggttttg ataaaaccaa tcttttctat tttcgttatt ctatatccat aaatagtaat
    14281 catatgaata tagaaacaac agacaactct cctttgctac aggaatgtat agaagaattg
    14341 atcaatagta aaatcgatga ggggaaagga agaaccgctg ggaattatcg aagcgcatgg
    14401 aataaattat ccaccttttt aggtccgagg gtaacggagt ttacatttgc agacttaacg
    14461 accgattttc ttcatcacta tcttttatgg ttgatgcaag gggaagacgg gaaacaggct
    14521 cccttgaaac cgggtagttt ggacttctac attcgtaatc taaagacaat gtacaacaag
    14581 atcgcccaag ataaacaaat ggatgttccg agagaaagcc cgttctctgg cctgcagata
    14641 aaggtcccac ccacccggaa aagggcttta ccaagcctcg acctacaaaa tctggcgact
    14701 cttgagcggc ccaaaaaccc acacgcctgt acggcccttc acttgactct tttcttattt
    14761 tacgctagag gtatgtgctt cgtggatgtc tttaatctgc gacacagcaa tataaacgat
    14821 gattatatcc actacgtacg tagcaagact ggcgtagcga tgcaagtaaa gatcaccccc
    14881 gagataaaga acatcatatt ctcttatcgg cgtttcaata acccgtggat attccctttc
    14941 ttacacgaga aaatcagcgg agagggagaa gtcacggctc agtccgcgct tcggagagtg
    15001 aaccgccact taaagaaaat gggagagcaa ttacacttcg aacagccatt cactacctat
    15061 gtgatgcggc atagctgggc ttccatgatg ctggaggcga attcggaaat cggcattatc
    15121 agccaatcct taggacatat gtccctacgg actaccgaga tctatcttgg ccggatatca
    15181 gtatctaaaa tagacagggc ctccgataat atgttgaaca atttggttcg cagctcttcc
    15241 acccgacaaa gaagtaaaaa taaggtgatg gctttaagag acaatcggca agaaatgcaa
    15301 gaagctcatt tcctcgattg cctctaagtt attctcattt atttaagata gttcatgcag
    15361 gaatgccaaa gggtagattc gtcaaggcat tcctgcacag cccttagaat ggatactatt
    15421 tctcttcacc aaaattaacg gtattctcga cattgtccac atcatcaaag acagccacgt
    15481 tgccgtttgt tatcgttaca cggaggtcgg cactattagg gccggcgata ttcaccgtca
    15541 gcttataatg ataatcttga tagatattgt aatcggtcac caagtcaccc caagatagaa
    15601 tttatactat ttatccgtca ttctgagagt tgtctctttc tgcgtaagaa agagacattt
    15661 ttttttctcc atacttcttt attctcaatc acttctgttt ttcgattcat tttacattat
    15721 cgtttatttt accgtttgtc tctttacatc tcactactca tttaacattt aggacttact
    15781 gtccgaaacg gcacgcacga ggtagcacga ttcccgacgg gggaaccgtg taaagatcca
    15841 tacatgcaaa cttcatattg ttacatgacg ttgaattgat aaggactagg aaatacgaag
    15901 gcgcagacat cttgccgtta tgtccgtgcc tttatgattg actaaaccgt gatcgcaata
    15961 ttacgatccg tggtttaaat gtctaattgt ttcgattttg tctatattca ttaggtgtaa
    16021 ccccaaccat tttcttgaac caacggctga aatgttgcgg atatggaaat cccaattcgt
    16081 aggatatctc gctgatggat ttggtgacat cgaatacacg ctctttcgct atatcgagca
    16141 tcttctgctg gatatgtttc aacgcagaaa caccggtttc ctttttcaga aggtcgctta
    16201 gatagttagc cgacaggcaa agcttgtcgg cacaatactg cacggtgggc gtacctttac
    16261 ttatgggaag attggacgca agataatcat ccagcgtttg ctcaaatcgg gctaagatgt
    16321 caagattcac attctcccgc gtttcgaatt gacggtcata gaaccgctca caataatcaa
    16381 gtaggagttt tatattgtct gtaatcagtg atttcgtatg cttgtctatg ggatggagca
    16441 attcttctct gattttgcac atgcagtcaa taatggttcg cctttcctgt tcagacaagt
    16501 ggagtgcttc attggcggaa taggagaaga aactatagtt tttgatgaat tgggctaacg
    16561 gagtgttacg taccagttcg ggatgaaaag cgagcagcca tccaccgggt tgatgcaact
    16621 gaccgtcatc gtcagacccc atgacctgcc ccggagcgag aaaaagcatc gtgccttgct
    16681 gatagtcata gatgctacga ccatatttga gagtaccaca gtccgggtct ttcatcaaga
    16741 tagcatacaa attatagagt ttcggacaga agtgtaccgg attagcctct cgcgcatcga
    16801 tgaccgtaac cagcggatgc aacgtttcca taccgaaata atcgttgtat tgctgcacag
    16861 tgtctattct ctttatctca ttcatcttca attgtatttg gcttcgattg caaagataac
    16921 cttttctttc atacgtttct caccgtccga tgaaattggt tattatatct gtggaattga
    16981 tacagtctac accccaaata accgctattt ttgtaactga aaacttttaa ataataatta
    17041 tatgggaaca agaaaaatta tctgtatggg aagcttattc ttcttgtctg tagccattcc
    17101 ctacgaaagg cagacaagta ttaggggtgg ctgttcccgg accatttgat caaactgaaa
    17161 ttgaaaagcg agaagatgtg ttggtatata caacacctgt actccacaca gccgtagaag
    17221 tgacaggaat ggtggaatta aagttgtatg tatctttcaa gcaattatag gaaagccgac
    17281 gaagctagct tactttaaaa caatggattt gaatggaaaa aattcataac tatgaatgaa
    17341 gaaaaacata gttatgaatt gaaaatttca tagttatgat ttttcagtat caaaataggc
    17401 aagtaattct tctatcgttt gggtgatata ggtaccgccg gaagtctcat ggatgataaa
    17461 gtgggtggtc tttaaatcgc cagtctcaat ccagatattc gattccactt cccgattcgc
    17521 caaaattccg tttcgctgga gcgctttacg caccatagcg tatttctggc catgtccaac
    17581 gaggcggatc tgtcgggaga attgattatc tatacggaat aatccggtat ccttatcgaa
    17641 aacaatccct ttccgggcga agaaattgct taaatgacca ctcaatgcca aatcctcggg
    17701 ggtaccggta gagataccat ttgctttgtc cattaaccag atcttatccg atatctggag
    17761 agccagctcc aaatcgtgag tggacataaa tatcgtctta ttcgttttcc gggttagatg
    17821 atggagtaat tgcataatct ctaccttgct gggaaaatca aggaatgcgg taggttcatc
    17881 caagtaaata accggagtct cctgagcgag cgccttagcg atcatcactt tctggcgttc
    17941 tccatccgat aaggtatgga ccatgcggga tgctagttcc tcaatgcgga caagggcgat
    18001 ggattcttcc acgatccgct tatcatcctt gctcaacttg ccccagaagc cggtatacgg
    18061 gctacgtccc atcccgacca attcccgtac caacatattc ctgatctcac atttatcggt
    18121 cagcacgaca ccgatcgtgg tgctcaattc cttatcggaa taagcatcta tatcttttcc
    18181 taggaccaat atttccccat ctaatttagg ttggaaagcc gataacgtgc gcaataaagt
    18241 agacttcccc accccgttag cacccagcaa acaggttaat tcaccactat agatcgtaga
    18301 gtgtatacct ttagctacca gctttgtact actcttagaa tggtaaccga tcgaaagtcc
    18361 gttaatatga atcgtatctt gtttcatctt actcgttcaa ttcattctta cgttttctaa
    18421 ataatactga ggccactact ggagcaccta ctaaagcggt taccgagttg acaggtaacg
    18481 ctccctcgaa ccccggcata cgggcgatca aattacagat caacgccaac gccgcaccgg
    18541 cgaataagac cgcaggcatt aaaatccgat ggtcggaagt ttgaaatatg gcccggcata
    18601 aatgcggaac ggctagcccc aagaagataa taggtccgca ataagcagtg acaatcgccg
    18661 taaggacccc agccgaggtg ataaccaaca aacgggcccg cttgatatta agtcccaaat
    18721 tgcgtgcgta gctatcccca agaagcatca agttcatggt cttgataagc aggaacgaga
    18781 gagggatcaa gattgtcata agaatcacga acaacgtcat ctgattaccg gaaacacggg
    18841 cgaaactacc caatccccaa atcacgtatg cacggatatc ctcctcgacg ctaaagaatt
    18901 taagtacacc gatcacggcg tttgccacgt aaccgatcat cacaccgata atcaacaacg
    18961 tgacatttcc ttttaccttt tgggaaacat acacgatcag cgccatcacg gataaggaac
    19021 cgatcacggc cgctatcgat aaggcgatct cccccataaa accaagttta ctcaaggcaa
    19081 cgccccctaa actaccgctt aacaacacca cgaaagcgac acccatgctc gctcccgaac
    19141 tgatacctaa gaccgaaggt ccggccaatg gattacggaa aacggtttgc atctgtaagc
    19201 cgctgatgga taagccagct cccgctacca acgctgtcaa tgcctgtggt agtcgggatt
    19261 tccagataat attctgccat gtaataggct catttcctaa attccagata atatgccaaa
    19321 ccgattgaag aggaatagag actgacccca acaccaaatt caaaaagatt agaacaaaaa
    19381 tagccgtgac aatcgccagc atccataggg tatttgaatg tctcatcagt gttccttatt
    19441 taagtcgaga ataatagacc gactcatgat ccggtaataa atccggatga aagatatgaa
    19501 gcaaatccgc taggacgatc tccggttctg tcggcatact ctcataaaac ggcgtgttct
    19561 tcatattaca atagataatt cctttctccc ggaacgcacg gaaatcctca taacgaggat
    19621 cttgctcttt caatgcctca tagctgaacg ttcccgggaa actattcacg atacgccaat
    19681 aatcagcgtc gtccgcttgg ttatagaccg tctcgaagtc taatgtaaca ccaccggatt
    19741 gctcatcatc tttcaagaaa taatcagcgc cggcatcctt gaaaagttgc gctaagaagc
    19801 tctttcctcc tacggcatac cagtttccac cccgtaactc gccactaaaa acgatcggac
    19861 gttttttaac cttaccatcc gccgtaagtt cctttaattc attatacctc ttctcgatgg
    19921 tggcgaaacg ctcattgcca tctttctcta tccccaacag caagcctacg aacttgatcc
    19981 actcggcctg tcccaatggc gtagtctcct tataacccaa atggggaatc aagggaatac
    20041 ccacgtcttt cagcgtctca tagcctcccc gcttgaatgg cgatacaagg atcaaatcag
    20101 gattcatgct catgataacc tcgttatcga aattcccctc gataccgatc ttagcggttt
    20161 taccttcttt caggcgttcg ttcatctctt tattgaacaa atgccgtgta ctggtaatcc
    20221 caacgaccct atccaaggca cccaatttaa taaagttcga taattgcagg gaagtcatac
    20281 agataacgct tcggatagga agctctatca ccgtataatc agcgggaatc cccgtgggtt
    20341 tcgcacctct tttcacgaac gcataatgaa acgtggtgct ttcctcattt tgaggatctt
    20401 ggatatcagc caagagatat tgatccgcat aggtaagctt gaatccttgg gcgtataaag
    20461 gcttaacctg ctcttgcgag aacgcagatt gctctacgga agccgtcttc cctatttctc
    20521 ctttttcacg gatacctgaa gtacatgata aagtcaatac cgataaaagc aagcatccac
    20581 ccgctataaa cttattcata atccttgttt aattgacagt tgatcattga cagttactct
    20641 cgtcctgctc cacgggacag caacatttat ttatgaaccg gcaggtcttc tgacttactt
    20701 ccattcagga cgccttcccg attacaaaac cagtggccaa ggtattgtcc gaatgtttaa
    20761 aagttcacag cagcgtggtc tgtccgggat tctcacccgg ttccctttta atccgcctcc
    20821 cggaaaaaga gataagcgga gcctgttaca gtgacaaaag tagtaagaat atttgtatac
    20881 atccacaatt ttaaggactt ttgcgtttca aataaaaaca gatacacatg aatcatccta
    20941 ttcacttcgt ctcattaggt cccggtgatc cggaattaat tacgctgaaa gggcttaaaa
    21001 cattacaaaa ggctgatatt atctattgtc ctgctacaca aggcaagcat ggaatcatat
    21061 ctcgggcgac ggatatattg aaagctattg aggtagacga atccttgatc catccgttta
    21121 ttttgccaat gagtaaggaa cggacagatg cgttaaacgc ttataacaaa ttgtttctgg
    21181 atgcccaagc tgaatatttg aaagggaaac aaatcgtgat cgtcgccgag ggagacgctg
    21241 gtttttattc atctatacaa tatgtatacg ataaattcga ggaaacagga atcccggtag
    21301 atcgaatcgc aggaattccg gcatttatag cggcaggtgc cttggccggg atacatatcg
    21361 taaaacaaga ggagcaaatt aacgtaatcc ccgggactgc gtcgttcgat gaactttcgg
    21421 caaaaataga aaatggaatg atcatcgtca tcatgaaatt accgggttgc caagaggcta
    21481 ttcatacttg tatccggcag tatgcggata aggcggtttt tcattatttc gagaatgtag
    21541 gaacaagaaa agaatattat actactgata tcgccactat acattccaag gatttcccct
    21601 atttctccct actgattatc caacctcgct aaaagaagaa ggctgcccgg agagtaacca
    21661 aacccggaca gcccatctta ttacgctaca tgcaatatat gcttaagctg atcgatatgg
    21721 aaacgaagtg tatccatata aggtttcact gaattatggt acatgaccgc ttttgcgtgc
    21781 atatcttcca actcgcttac tttacggttc gcctcacgca ttttacaagc gttgtagcga
    21841 atacccgata catgtccttt gatatcctcg atcgcttggt ttccccggtt gaagatagac
    21901 tctgcttctt ccggagcgta taccgtatag gcttgggcaa cgtcatccag taacgcctgt
    21961 tgataagagc cggctatcgg gagcaattga tggatcgcat gatgacataa agaatgaacc
    22021 tcgttttgaa gcttcttcaa ttctacttcc cactttgatt cacatacttc atccaattgt
    22081 ttgacttccg ctacgacacg accgctaaac aattccacta ccatcttttc ccatgcttct
    22141 gctacccacg atttagtagc aaatgtaacc tgactaaatc ttactgttga cataacctta
    22201 aatttacata ttatattgct aatgttatta gtctcttatc tgtttcaatt tatcacactc
    22261 aaaccatttt aggtttcttt ttatcgttgt gacatcacaa aattaatcaa attattacag
    22321 atgaataatt ttaaagacta ttttataatt ctttaaaagt acaacaagca aaacgtatga
    22381 tttttgcaaa gctcacttta caaaaagttt aatttcaagc ctgacagcta tcacaaaaag
    22441 caagatcctc gccatcttcg cacaaaaata tcaaaataac acaatcttat tattccataa
    22501 agggggaaaa ccttgttccg tatcattttg ttattataat aaattagatt tactttgttc
    22561 aaactatata aacttacata aagcacatga aatcggacat tgagatagca agagaaacag
    22621 acttgcgtaa aattaaggaa gttgcgacaa cgttaggtat ccctcgtgag gaagtacaaa
    22681 attatggcag gtatattgcc aaggttccta tccatttgat cgataaaaag caaatggacc
    22741 agcataattt aattttagtg accgctatca ctcccactaa agcgggaatc ggaaagacta
    22801 cggtttcgat cggtctggct ttagggctga ataaaatagg gaagaaagcg gtggtcgctt
    22861 tacgtgagcc gtctcttggc ccgtgtttcg gcatgaaagg tggtgctgcc ggaggtggat
    22921 atgcccaagt gcttcccatg gaaaacatca acttgcattt tacaggggat tttcatgcgg
    22981 ttacttccgc ccacaatatg attaccgctt tattggataa ctatatttat cagacccgca
    23041 acacctgcga gggattgaag gagatcaaat ggaaacgggt tcttgacgta aacgaccgta
    23101 gcttacgtaa catcgtatcg ggtctaggcg gctcggcgaa cggtgtccct accgagaccg
    23161 gatttgacat cactcccgct tcagagatca tggcgatcct ttgcttggct acggatatag
    23221 aggatttgaa acgacgtgtc ggaaatattt tattgggtta tacaaacgaa gataagcctt
    23281 tcacggtaaa tgatcttggc atagccggag ctattaccgt attgctaaaa gacgcattac
    23341 tgccgaacct tgtacaaaca acggagaata ctcccgcatt tgtacatgga ggtcctttcg
    23401 ctaatatcgc ccatggatgt aattccatat cggccaccca aatggctctt acttatggag
    23461 attatgtgat tacggaggct ggtttcggcg ctgatctggg cgcggagaaa ttctttaata
    23521 tcaaatgtag aaaagcgggg ctttcaccga aactgacagt catcgtagcg actgcccaga
    23581 gcttgaaact tcatggtggc gttccggaga aagaaatcaa ggaaccgaat atcgaaggat
    23641 taaagaacgg attcgctaac ttagataaac acattgagaa tatgaagagc ttcggccagc
    23701 aagtaatcgt tactttcaac cgtttcgcta ccgatacgga cgaggagatt gcgttagtgg
    23761 ctgagcattg cgaggagaaa ggggttggat tcgccatgaa taacgttttc gccgaaggcg
    23821 gtgaaggggg tacggagctt gcccgcttag tggttgatac gatcgaaaat catccttccg
    23881 ctcctttaca atatacatat gatctgaatg atccgatccg tacgaaggta caaaaagtgg
    23941 cccagaagat atacggagct tcttcgattg tttatacgac tttggccgat aaaaaattgc
    24001 gtcagatcga aagcttgggt atttcccatt atccgatctg tatcgccaag actcaatatt
    24061 cattctcttc cgatccgaaa gcttatgggg tcgccaaaga tttcgaacta aaagtacgag
    24121 atgtaatcat caataacgga gccgagatga tcgttgtcgt catgggcgag atcatgcgta
    24181 tgccgggact cccgaaagag ccgcaagccc gaaagatcga tatcgtggat ggcatgattg
    24241 agggattgag ttaatagaca gtaaaacgat tcaaataaaa aaggtgcgcc tcacacattc
    24301 agtaaggcgc accttacttt tgcttattta tgaataaact ttatagaacc tctagctgta
    24361 tttagcaaat agattcctgc tggcaagcga gagatgtgtc aatacgattc gacttactct
    24421 ctgccatttt ccctccagtt atcgcataaa tagaaatccc gctttccgtt ccttgtactt
    24481 ccaacacatc tccataaata tgaagtttca gttcgttctc ctctactaca ggagcgatag
    24541 aggttgttcc attgaaatag tcatgtgtct ttcctgaata ttcccagctt gtctcagcgg
    24601 ggaaatacat tttctgataa tttttcgaaa tcatcgggtt tcccgcgtcc acgatctccg
    24661 tcttgctttc tgacataagc atccaactac caccgaaatc aatggaagac gaggttttcg
    24721 tgacattctt atcgtaagac cactccattt tcatcttgaa cgtctctccc tcagccgtac
    24781 ctgtcatgag tatcgagacc ggatatttat ctttgttgaa agtggcttct atatccactt
    24841 tcgcctcggc tttccatgcg cctccctcaa agctggagga agtgacggag aacttctcat
    24901 agccatttcc ggtataagtg tattctgttt tctcgcctgc cacgtcggct gccgaataag
    24961 agatagcgac caaagtgcgt ccttggttat cattctccat cacggtcttg ccatcatata
    25021 cccaatcaga cgaacttgag ttccatttat aactgtctat acgaaccacg cttttattac
    25081 catcgcatat ataaacatct ttctgttcct gcgcatcgtt cttgtcatag gtaatactat
    25141 agtccggaca tcttccaaac aaataccccg gaagagagaa tgattgcgcc atcaatgaag
    25201 aaatacctac taaacaggct accaatgtaa ataatactcg tttcatattc ttgatttttt
    25261 acgattaaac ttaaaaacta taacctttct ccgcaattcc cgcaaaatgt agcggtcgga
    25321 gctaattgca ttccgcattg agggcaaaag cggctttccg gcgttgagac ctgtcccggt
    25381 atctgcggtc gcaaaggatc ttgtgctgcg gaagtagcgg tgggattcgg ttgcggcatc
    25441 tcgttacctt tcttgaaaag ctccttgaac ttaccggaca agccgctcaa cttaccatac
    25501 agatcgaaag taacttgcgt ggcgggagct acttgcatat agctgctcat cattttcacc
    25561 aagatccagc tatcaataaa ggcatacttt actgtatagg cgaacaacaa tgaaataatg
    25621 aaagccatga aaccgctcca gccgaacaag cggaacaatc caccgaagag gataaacgca
    25681 atcaacgtaa ccaccacgaa cgataagatg accatccccg ttgtcttcgc cgcatccttg
    25741 agcaacgtct tccagttctg aaaatagata atgacaccat ctgccgccga tttataaggg
    25801 ttttgagccg gatggtaaaa ggtgtaacct aagcagcact cgtccacata ccccaacgag
    25861 atatcgagaa acatgttggt gaggctcttt atcccgtcag ctccggggag cgccccgagc
    25921 aaactgtccg taacacgtcc caacgtacgt tgtaactgtt taatggaacc cgccacaagt
    25981 ttatccaagg caaaatacac gttggatgta ccgaaacgtt cctttaccat cgtctttccc
    26041 atctcgaagg gtttggcagg tacatagccg gtttgatacg ccatcgcgat cacggccaca
    26101 tgcccggctt ttacgagata accgatgtag tgattcaaga agaaattcac tacccctata
    26161 agtcccaacc agatgaaaaa catgatcgct accactccgt cgctattgaa caggaccgat
    26221 atgcccatca agatagcgaa gagcagcacg gctatcaata tattcagcaa tcctaatcct
    26281 agttttatcc aaccgaattg cagggtcttg aagaaaatct cttttgctgt cataaagtat
    26341 acatttatgg gttattatgc tatttcaaca gacggtattt accgatgata ggtaattcct
    26401 tagctcgccc gttcagcgcg ttaatgatac cgatgactgc cagtaccgta aacacgatgt
    26461 aaacgaggtt caataccgta ccgcaaagag agtagatgct ccataagccc aatcccctcc
    26521 ataggatcgc ccgcaagagg gcggtcagaa cggagtccgc tatgatccag ccaaacatgg
    26581 cgatgcataa aagcaagcct tggttggcat ggaaccgggc gaatttcgag tccttggccg
    26641 caaggatcgg gatcaatacc agaatcccga aataagcaag gatagccatt accttatttt
    26701 gctctacatc ggctttatcg aactggtcgg tcaggtccgc ggtcttgttc ataccactta
    26761 atttgtcgct caaggcatcg gccgtggcgg tagccttagc cattgattcc gcatcggtcg
    26821 gttgtaccgg cggaggtgtc tgttgcctgt tcggttcggc ggcaactatt tgcataggtg
    26881 atccgcaggc cgggcaaaat ctcacgcctt cattcacttg ttgtccacat tttccacaga
    26941 atgccataat ttgtttcctc ctaattttag tattgttatt atttgagtag atctccgaaa
    27001 gcttccatca agctgtctat ctcgctaccg aacagcatcc gtacggcgaa gaacatcagc
    27061 aacgacaaga ccgaaccgat tatcatcatg atcagcatcg cacgggcgaa gttcgccttg
    27121 ttcaccttct ggcagcctcc gcaggcccag ataatgagta ggatgagatt gatcaacgga
    27181 agaagcatca acaggaagat accgatatac ccacccgtcg tgatcggttc atacttgctt
    27241 cccgggggaa gcggagcgtt cggatcgccc gccggagcca cgtatcccgg ttgaggttgt
    27301 gcgtaagccg gttgcgatgg cggggcataa gcctgctgcg gtagtggctg aggcgcaggt
    27361 tgcggctgca cataggtttg ctggggcggt ggcggggctt gcggttgtgc ctgtaccgac
    27421 atcggcgtac cacatgaggt acagaatttt atgccatccg ggacatttgt cccgcagttt
    27481 gtacaaaaag ccatgatttc tcctttcttt aaagtaactg ttatacatca ttccattttt
    27541 gttccgcaac cgctgcagaa acgatgcccg gcgataactt ccgtgccgca gttcgggcag
    27601 aaacgtttcg ccgcaggcgc ttgttgcacg ggttgcgtca aacgggttcc acactcttgg
    27661 caaaagttgg ttccctccgg attataggcc ccgcaattgg ggcagctatg ctcctgctcc
    27721 tcggcttccc ggcgggcacg ttcctcggcc tcggcacgtt cgagggcggc tttccgccgc
    27781 ctgcttgttg gctgcgagta aatctagctc tgcccttatc tccggatagt tctcgccgcc
    27841 atccgtctca tatacttgcc gtccgagacg ggcatagatc tttccctccc tttccgagaa
    27901 ctctttcatc tcggtctggg cattgaatat cttcacgtcg ggatcatcct gcagcatgaa
    27961 tccggacaag ccttttacga ttcctgttaa aatatctccc ataccacctt actctttctt
    28021 agttcctttc gccttatccg agaaatctcc catatccaga ttctttatcc cgaccttcgt
    28081 ggccagcgcc gtcagtttcg tcaccttggc gattatcttg atcttggtga cacctcccac
    28141 ctcgttgtct tctatcgttt tgttcaatac gctaacgggt tcctccaagt ctttcatgat
    28201 ggcatccatc tcgtccttgg tcatcttatc tccttttttc tccagctttt caatggcatc
    28261 atccagtttt gccaaggctt tatctaccgg cgaacctccg catgccgtca taagcacgag
    28321 gcttatgatg aacatgaatg taaataatgt ctgtttcatg atacgtatgt ttttaatggt
    28381 ttacaatcct tctattgaaa ctagctcttg gcttgtcatc agttttccct tcttgttata
    28441 catgtttgtc ttcacagggc caatgccgtg gccataccag atcttctgga tagcggtctg
    28501 cttgataccg atcactttcg atacggtagt gttctcaatc acgacgcagt cgatactcgt
    28561 cccgttcacg tcgagggttt cctcggccac ggccttcacg cccgtcacct ccgtattggt
    28621 cttgatgccg gccaagttca aggtgatggt atagtcgccg aaggtatcgc ctaccttgac
    28681 attggaggga agttggaagg gtgttccggt cacggttact tgcatgccct ccatgatctg
    28741 tcctaccaac gacttgggat cgtaggtcac cgtgccattc ttcacctcga atgtctgtgt
    28801 catcggttgc ttgagcaccg ggttcttttt attgtccatc accatcatcg agtaggtaac
    28861 ggtgcagttg tccgcgtctc ccgtcacctt tgtagcggta gtctccgtgt aactgttgat
    28921 ctttcctttc ttgtccttgt cggcgtaagt cagtttcacg ccttccttat gtaggaagaa
    28981 aggttcttgt gcgctcattc ccaataccgt cagcaaggaa acggcgatca taactagaaa
    29041 tctaatgttc gttttcataa tcgttgttat tttaaagtga ataatttttc tctatttctt
    29101 cttctgtccg cccagcatct cgagcaaggc cttcatccgt tcctcgtcgc tcttgctctt
    29161 gtcgttgacc tctttcagtt gctccttgat ctgctcattg gatttttgga tggcatcgcg
    29221 tgtctcgtcc actttttggg tgttctcctc gcacgatttc cccgtcatca tctccagcag
    29281 gccgccggca ggcatcacag tcatttgata cccttcgggc acttggaaga ggtgcgccgg
    29341 ttgcggcccc atcttgacgc ggcgaagcac gatggtcctg tccatcacat acaccgtatt
    29401 gtcgtgggcg atgcagccgt tgtagttcga taccttcatg ggcgagtaaa tccattcgtg
    29461 atagccggcg ccatccttgc cgccatcctt gtagatcgat tcgctcttga catagtagtg
    29521 ggcacactcc ttaccgtcta tctcctccat gcccaaaaac tctcgggagg tagagtgaga
    29581 cacttcccag tcgtaaccca ccagcttatt ggtggataac ttgtcgatct cctccatcac
    29641 catgcaggtc ttccgggcct cgttcatcac gtaggctttc ttttccttca tatcgaagat
    29701 catgatggtc ttttcgccac tccctttccg gcaccactca ccatagaaag aaatttgcgc
    29761 ctgcgccgcc gtcgttacgt acagcgcgca tatcaataat aagattaacc ttttcatgtc
    29821 cattcctttt agtgttgtta gtaatcatcg tcccgggcta gcttggaaag cgagccgcgt
    29881 tctctccctt tgtcgggcag gatatccacc cttgtatcta cgtccaccag ccgggagaag
    29941 gctttcaggt cctcattgct gaggcgtatg cagcccatcg ttatccgtcc gggtatcact
    30001 tgggggttgg cggtcccgtg tatgccgatg cccgtgaagc cgggtgtttt caagcggaag
    30061 aagcgggggc cgtatatctc gccgggagtt tcttgcctcg tcgagtctcg cggccaaagg
    30121 gaggtatctt ccacggactc tatcacgaaa tgcccttccg gtgtccggaa atcccattcc
    30181 tgctgcttgt cgccgtaatt gcgtccgcaa gcgatgggaa aaacggcgag cgtatcgcct
    30241 tgcggacaaa gaacggttat ccgcatatcc tgtttggata ctatcacccg gttcgtgccg
    30301 tccgcttttt cttcctgcgc ccgtagcgtc gccatcggca ctcagaggag tgccaatagc
    30361 aacaacacga tccggcgtat atggcaagag aaaatgttca tcctgttcct gttttaatgg
    30421 ttaccttaaa tctcacccgg gctttccgag tctccgccgc cctccgggac acctttggcc
    30481 aaacggtaat cggctataga agcgtagctg atgtcgtcct ccagtacgcc gccgtcctcg
    30541 aacgtaaggc cgctgagcac gctctcccgc aattctttcg agggagtgaa tacgatccgg
    30601 acgttcttga tcatgctgtt cgcccggaaa ctgttaatat cttccacgcc atcgctcttg
    30661 aaggtgaggc gaaaagtacc caagcccggt atcttcaccg tgtgtccctg ctggagttgt
    30721 tggggcacga acttggccag aagctccagc gaggcctcca tctcgatggg agcagtagtg
    30781 gtgttggcgg tggcggcgca cgtcatcgcc ttgcccgaga gcggggtctc gcttttgggg
    30841 gtcgcgtacc atttgccagg ttcctgtctt ttctgcggat tcactttctt aattaacttg
    30901 tactttgcca tcttgttttg ttttaaattg ttgataatgt gataattgtt atttctctct
    30961 attctcgttg ccggtcttgc aggcgtgagg ctctaggtgt cgcacgtgtg aggcagctga
    31021 tgtcatacgt gtgacaccgt taacgtcgca cgatggtctt gctcgtcgat gactccccag
    31081 cgttcccctc tggccaccgt cgcccgattc accttgcatt tgtgcgggtg tttgcttcgt
    31141 ctcggtgttt aattgattct ccataagcgt attatactct tcccagagga tattgaaccg
    31201 ctcttctcaa cgacgggcat ccgcacgagc ttcacctgcg cccacgatac ctccgtcgcc
    31261 caaagaaggc agagggcgat ggagggaagg aatccatatt taccgtaatt ggccatagtc
    31321 attcttttta tcgttcgttt ctttaattct tgtcacttca taaggggaag ccggtgtcgg
    31381 gaatcggatt ccccggaagc cagagggaag gaatccctgc gcttccggag tctccgacgg
    31441 gtctaccaga atctatcccc gtttgtgtct tgctttcaca tagtgctgga acgatttgaa
    31501 gggagggaaa taaaaatcat tccagcatgt cagagagcta tcttgtaata aaagaccgct
    31561 atctcggaat aagcgtaacg cttcgttccg ggagtcggta tgaaatcagt atggtagaag
    31621 cggcgggcgc ttttgctacg gatgcactcg taggtgccgt aaaacgaggc gttgtaggcg
    31681 gtggagcaaa agcggacttg ctcgatatcc tcctcctcgg ccagttccgg gaaacggcgg
    31741 tataacagtt tcaagaacat ggccagataa atacattgcc agttccggtc gtccagccgg
    31801 agtacgcata tgcggtgggc ctccaacgtc tcggagagat cgaaatagat cccgtactcg
    31861 tgtcgccatt ccgttcgcat ccactgtcgt tccagatcct ccacgaagga aggcttcatc
    31921 tggaagcggc caatggagaa atcggctccc tttaccccct tttgctggta aagcgccttg
    31981 acggctgttg tctccataaa gtccatcaag gccgagtaac gaaccaattc ggggaagaca
    32041 accgccacgg ccaactccgt ccggataccg aactccggga agatcaagtt ccagacctcc
    32101 cgttatcccg ccacgtactt atcagcttct atccattcct tttcaaagat cttttggcaa
    32161 tcctgcgcca aggcggtcga tccgctgaga gctcgcgcca acaacgcaac gaggaatacc
    32221 gctatagttt gtacgtgcat ttttcaacac ctgcagacga ggcgatgatc cacaccagcc
    32281 tgtcgctctc cttcttgaaa gccagcggat agaaggaggt gccgtcatgc agggtaagcg
    32341 atccgtcgcg cgtgtaggtc accttgcgtg tgccgctagc cgaggtccaa gctccgtagg
    32401 tgggttccgt ccgtgcccct ttcgcttgga aatcgccggg atcgttcggc cccagttccc
    32461 gcttcttgcc gttttcgtaa aggtatctct tgcccgcatt gtcggcggtg tagacgcggc
    32521 tgttgttcaa gaagccgtcg accgacgtgg cgaaaccact ctccgcgtaa aacaggtgct
    32581 caccctcggg aatctcaatg atcgtctcca tgtagaccgg caacacccgc ggttgcggga
    32641 agtcgcgata cgccttgtgc aagatattgg tgtaattggt cacggcgttg aacgaggcac
    32701 gtttctcggc gcaggtcggg atgattccct cctgcatcat ctctttctgc aacttcacga
    32761 tgtccggata catggccttt accccatcca attgggtttg caggctgttg cgccagagct
    32821 tggcggcacg gaggcgatag tttttcatcc gctcgtcggc acgggcataa agttcctcaa
    32881 ccttctggct gtcgtcggtc tcatagattt gggcatagag ggtctttaat tccgattcgt
    32941 attccccggc gatcttctcg caactcgtga ttgcgccatc gctcgcctgt agtatctttt
    33001 tcatcttctc ggtttgctgc acggtcattt gttccagctt gacgaacttg gcgttgaagg
    33061 ctgtcgtttt ctcgttcgtc gcctgcattt tttccatcat ggaacctagg tcgctcaggt
    33121 tgccttggtt ctccgctaag aaggccatct tctcctcgtt ggtcaacttg cctcctttgg
    33181 ctgcctcacg tttctccaga ttggcgccca tggcctcaag cccccgggta tcgcctacca
    33241 aggcgttctt catcttctcg atcaagcgtt ccttttccgc ttcggggagg ttcgggtctt
    33301 ccaagctttt catttcctcc accgtaatcc cgttgatatc ggccaactct acatagaact
    33361 tatcccggag ggcgatcatc tcctcgtccg agcaggtatg tatcgaatcc agttccgtta
    33421 tacgcatatc cacggctacg atcttgcggt agtaggtcgc acgggcggtt tcctccgggt
    33481 agacgatgct ctcgacggaa ggcaacgggg gaagctcgtt cagcaaggcc tccggcgagt
    33541 tggctctgct gggagcgatc atctcgtccc acgtggcggt agccgtgcga cgtttttgta
    33601 gcttatccgt gggggtgaca gatcgtgtcg gctgatcgcc atctccaccg acgaaaggct
    33661 cctctcctat ctcggcggta tcatccttgg tacctactac gttgcccact ttctgtttca
    33721 gtttcttcaa gaaactctgg ccgtgcacct ccaccggtat cctgcagaat atcgcaaggg
    33781 cgattgccat gatgttcaag atctttctca tcgttgtatt tgtttataag gtgaatattc
    33841 tgtcgtctat tcgtatcgga tacgctccca tttctccacg tcatccaagc tttgatctat
    33901 atgtatctgg atgctcccgt cgggcttgcc tccgaatccc tccttgggga tcgggtcgtt
    33961 cacgctaccc tggctgcgga aagggatcgt tcccaatccg ctgatgctaa gcccgtcgtt
    34021 tatgttccca tcgatgacga tgaaatctcg cgtggcgtaa taattcaggt agtgatcggc
    34081 tttgaacgat attccctcat cgctgaccgt accggatacc gccacgttat gctgcaactg
    34141 gaaataggtc tcgatctctg gctggggctt gtcgcccggc atccattccc tgtctcccat
    34201 gaatacttcc gtgctggcgt aaacagattt ggtcggtttc ttaggcatat tcaccaccac
    34261 cttcaccggc aggcggtata tgttgtgggc ctgcgtgggt ttcgtgctgt gcttgaagcc
    34321 aaggccccag ctctccgccc atagtttcat atacgactgg tttatcctta tatcggaggc
    34381 gaacatcggg gcgtctccaa cgatcgttgt ttgtccgaaa cgtagcagtt ccttatccac
    34441 aaaatagtgc gcatcccaat tctgcataca acacctcggc gtccagccac ccgatgtact
    34501 caccagcgaa agtcctgtag aactgctgct ccgtcagttt ctcgttggcc ccgtgataac
    34561 tcttctccag ctccatcttg atcttccatt gctgtacgca catctctccc tcataaaaga
    34621 aaggagcgtt ggccgaaccg ttcacgcgca gcacccacgt ctgtcctttc gtttgcgcga
    34681 tctgccacaa gcggttgttg gcgatgcgat agaaacgggc gagcgagacc agattgtcct
    34741 cggccacgca gttgatccat ttctgcttat cccgttctcg cgcgttcaag aagatctcga
    34801 cacgcccttt caggctgaag atcttaccca ccgtgctgag tgtcttattc accaagtatt
    34861 tgtacgcctc gctcttgagc cgtccctgta tcctctccgc ctcgtaatac ttgtcgcgat
    34921 ccttcacgcc gctgatca
//
LOCUS       DBMDTB010000031        34679 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_504_length_34679_cov_12.152207, whole genome shotgun sequence.
ACCESSION   DBMDTB010000031 DBMDTB010000000
VERSION     DBMDTB010000031.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 34679)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 34679)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34679
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_504_length_34679_cov_12.152207"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            2..1018
                     /gene="msrB"
                     /locus_tag="ACZPB4_07035"
     CDS             2..1018
                     /gene="msrB"
                     /locus_tag="ACZPB4_07035"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HIR1098009.1"
                     /translation="MSDQLSKTTRMNTQSEIYFAGGCFWGTEHFMKQIDGVTNTRVGY
                     ANGKMSIKNPTYEQVCNDNTGFAETVEVSYDPRQADLKLLIELFFKTIDPTSINRQGN
                     DIGSQYRTGIYYTNTDDLPIIKETVEALAKNYTKPIVVEIQPLSNFYPAEDYHQDYLD
                     KHPDGYCHISPDLFDFARKANKGKASNKPVSQKKFQKTDDQTLRSKLTAEQYAVTQQN
                     ATERAFKNEYWNEKREGIYVDITTGEPLFISTDKFDSGCGWPSFSKPIDKSLVMEKTD
                     LSHGMKRIEIRSKTGDAHLGHVFNDGPADKGGLRYCINSASLRFIPKAKMEEEGYADY
                     LPLL"
     gene            1135..1944
                     /locus_tag="ACZPB4_07040"
     CDS             1135..1944
                     /locus_tag="ACZPB4_07040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6597 domain-containing transcriptional
                     factor"
                     /protein_id="HIR1098010.1"
                     /translation="MYHEFTPCAALAPFIDKFWVFKGFTDIGTRFKILADGCTDFIFS
                     IGNMTVPTDEHSMIMQPYRSYFVGPMRVYSDLTATTNTLHMLGVRFQPCGLAAFTNEP
                     LGQFADLRIQSSDINLLFDNAFAEMLCEQPDDSVRIRIIEGYLIRLLTQSIQVDRQII
                     YATSFIKQSRGQLPVQNLIDKICICQRHFQRKFKDATGYTPKEFSRIIKFQYAIEVLR
                     NAPHTDLSSIALDCGYYDHSHFIKEFKRLAGDVPSYFLTLPNPTDEPLTYI"
     gene            2055..2924
                     /locus_tag="ACZPB4_07045"
     CDS             2055..2924
                     /locus_tag="ACZPB4_07045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HIR1098011.1"
                     /translation="MNYTFELKELQATHIVYLHHQGDMSLIPSSIRKLMQWAGPKGLI
                     NGPANKLISVYQHEGKELSVDIGLTVPQEVEGESEISKGLLSGGLYAIGHFEIGTDEI
                     PAAWSLMYTLTSKHQCKPCAGKSFEIYQSIPLDQHPQDKCMIDLCIPVQMIDLKLIEE
                     KAISILTECDTAMLASVTEDGYPRPVPMGKIKADGISQIWFSTGTFSDKTIQFQLNPK
                     AGVCFMKGGDSIVLTGKVEIVSDMEIKKALWSDWMFAHFPGGVIDPSYCILKFTSEEA
                     TYWIDNEFVKASI"
     gene            complement(3041..3898)
                     /locus_tag="ACZPB4_07050"
     CDS             complement(3041..3898)
                     /locus_tag="ACZPB4_07050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009038671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HIR1098012.1"
                     /translation="MRIKTTTKTEYQQRINVLVEYINNHLGEDVDLNKLAEISGFSRW
                     HFYRIFAEFLGEPVGTFIVRMRVETAARLLRYTEIPVKEIAYKVGYDVPSSLSKVFRQ
                     FYGISPNEYRNNKDYVIMEPNRIMPDMELKVEVKDLPGKQVAYIRLNGGYKEIDYPGT
                     WMRLLQFAKEQNIQPLSFSPICLYHDDPKVTSPDKLRTDICMEVAPSVCPKGEIGTKK
                     VLEGRFMVALYKGTYQQLGAVYDTLYGKYLPEMGLSLREVPSGEIYLNDPRNTKPEDL
                     LTQIYVAVE"
     gene            4046..4696
                     /locus_tag="ACZPB4_07055"
     CDS             4046..4696
                     /locus_tag="ACZPB4_07055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HIR1098013.1"
                     /translation="MLKITAPRLVKNLREDVDWMDCISRQEDDFTECSFNGLCVEDVS
                     KQNLSVNSCLFTNCGFIACNYRKSQFSDVVFKNCDLSNINLSGCGFYRVEFIGCKLTG
                     TNFSESIFNHTTIRDCKGDYVIFSMSKLRNVSFNQCFLRGGGLDNCQFTNVEFEHCNL
                     VEAELHRTSLKGIDLTSSEIAGIRIGSIPGGELKGATVTSLQALDIARMLGITIKD"
     gene            complement(4693..4953)
                     /locus_tag="ACZPB4_07060"
     CDS             complement(4693..4953)
                     /locus_tag="ACZPB4_07060"
                     /EC_number="2.3.-.-"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIR1098014.1"
                     /translation="MEYTVNHYPDKHRFEVVEDGLTAYVEYRLRGDALDIIHTIVPKP
                     LEGRGIAATLVETAYKYAKEQGLRPLATCSYAVVWLKRHPEF"
     gene            complement(4957..8196)
                     /locus_tag="ACZPB4_07065"
     CDS             complement(4957..8196)
                     /locus_tag="ACZPB4_07065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AsmA family protein"
                     /protein_id="HIR1098015.1"
                     /translation="MSSRIRKILKHTVIAVLSLAVLFLVLNLFLTGRLERYLKRELIE
                     RTANATDGFYRLSFDKLSISFFKGELRLEGISLEPDSKVFEHWAALDSLPDTYVSTRI
                     EVIDFKGINLVWRWNYRQLHFNTFEIRSPEVRVYGSSGSNPLVSGLAADTVEHAESKT
                     LYEVISPYIDALSVKTLNLENASISYNVENQVSPIIYTLNNVSFHAYGFMLDSTSSRS
                     GKLLYCDNFDFVTNQPQTLLVNNDFRLETDSICLSTQDSIIYIQKIQLLPQELLWGET
                     NRKPTNYLEGKVQTVEIQGIHFRREEALNYLSARNFEIQSSDIKVYDLTREKKQANAD
                     ADSLVQALSLYDVISPVLHSISVDQIRIERTALHYSLALKGQIEDFSIPEFNFHAEGL
                     LIDSLVAPGEELNYFRSIAFEANDIQGIMRARNHRFDIKRLAMNTALGSFHIDSMRLR
                     PLSVRSRNDYLSGSIDTIRIDGLAYDKGVSADLLKVRSPRLVYYKTPSVESPDKGKST
                     SVNSRVDVESLLNPFLRYLSIRKIQIQNANVTLEDREINDTTRYRLNGLNFFATNFLV
                     DEQTNRSGQLFFKYDHFGLSFRDFDNYLPGKDLRVTIRKGSLSTVNGSFRLQDVTLAA
                     KKDSIRFSTPLISLTGIRIPKNSIYQIGFDRFDLSDGDFSMSWGSDTTILRTESQKDI
                     QLALENVFVDLKKKTFQLGDLQLQTKDIDIPLDNGFYRLKIGGLDLRESGLRLDHVHL
                     VSPYSKMEFAYKQPKHQDWFDVKVGNVRLTDVDIPGYFSTKELHVGGLWINDVLLQNL
                     KNRKIPVEPHIVPMIYEGLQKAPVRFKIDTASIANFSVVYEELPVKGDKPGKLYFTDM
                     NGQFSGLTNIVSYPEQFIRLHADGNLMGSGHFTATWQLPVDSLYDRFLLDACLDSLDL
                     LSLNEIIKPLAPAEVVSGWAQDVVFHMDASSRKGRIRLDFPYRKLKVALLKEKDGETT
                     QKGFLSRLANLVLRDNNPAHPERKDSKLRKVDMEIVRDPYHSTFNYLWQMLRPALVES
                     VGVSKKEQDAALKVAGFFTKVKRFFGLDKKKDKREEIDTNNKEIEPLKE"
     gene            complement(8328..9332)
                     /locus_tag="ACZPB4_07070"
     CDS             complement(8328..9332)
                     /locus_tag="ACZPB4_07070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HIR1098016.1"
                     /translation="MSNRRDFLKNISLFTAGGLLAGKAGSVNAANAALGVVDEVHASK
                     EIGLQIYSLSQELYKGDVAANLRKVKDMGYSKLELAGYGKGAIGGVPMMDFKKMAEDA
                     GLKIISSHVNPVDTSISDPFKAMIFKYSKEVTPKIMEYWKATAADHAKLGCKYLIQPM
                     MPTITTHDEAKLVCDIFNQASDVIKAEGIATGFGYHNHNMEFNRVATKEQQEKVKGNP
                     FAAFMKVGDQIYDLMLKDTDPSKVYFEMDVYWTVMGQNDPVEYMQKHPDRIKVLHIKD
                     RAVFGQSGMMNFEMIFKQMYANGIKDYFVELEQMPDGRTQFAGVKDCADYLIKAPFVK
                     "
     gene            complement(9356..10804)
                     /locus_tag="ACZPB4_07075"
     CDS             complement(9356..10804)
                     /locus_tag="ACZPB4_07075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HIR1098017.1"
                     /translation="MKENTKKGVSRREFLGLSALGLASLTILPSWAIDGVRIAPSDRV
                     VLGFIGLGQQALSDFKGFAACPGVQVAACCDVDTMKTERFRRRVAEWQASKGMNQRCD
                     QYEFYEDLLERKDIDAIEVATPDHWHALATIHSCQSGKDVYCQKPLAYTIAEGLAMVK
                     AVRNNKRVLQVGSQQRSSREFQAAIDMVQNGAIGHIEKIYARVGEPPTPLSLPEMPVP
                     ANLNFNQWMGPLNDPKIHYHPDLCPPISLDPEENEKLWGAWRWYQETGNGYTADWGAH
                     MFDIAQAAIGMDGSGPVEFTPKGYNGTQYSTMRYANGIVMTEQPYLEDNPDAQGIKFV
                     GDNGWIEVARGYINCSDQSKIPSDLKNLIEKRPRMMTPEERKKMYEEYMKKLKDSKKK
                     GNDAGNYETSAPHMQNFIDCVRSRENPIAPVEVGCSTNTLCCLQNIARELGRPVKWNP
                     ATLSFGNDKEAASHRLYWYQYRNPYSLPYFCK"
     gene            complement(10955..11737)
                     /locus_tag="ACZPB4_07080"
     CDS             complement(10955..11737)
                     /locus_tag="ACZPB4_07080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0015288 - porin activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="porin family protein"
                     /protein_id="HIR1098018.1"
                     /translation="MKRYIVLIGILCLSGVITLKAQQERNQGIIWSSLRGLEYTVKAG
                     INIGGTAPVPLPREIRAIDSYRPTLCVSIEGDIKKWFGESKEWGMMIGLRLENKGMET
                     KATVKNYSMEIIGSGGEKLKGNWTGGVQTKVENSYFSIPVVALYQLNNRVSFSAGPFV
                     SFATNRNFSGYVYDGYLREINPTGTKVEFSGDNRASYDFSDNLRKFQWGAQIGTEWKA
                     FKHLIVYADLTWGLNDIFQKDFDTITFGMYPIYLNVGFGYAF"
     gene            complement(11751..12845)
                     /locus_tag="ACZPB4_07085"
     CDS             complement(11751..12845)
                     /locus_tag="ACZPB4_07085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PCMD domain-containing protein"
                     /protein_id="HIR1098019.1"
                     /translation="MKVQSFVLCFLLTLLSVSCIREEAPNAEADILSCTVDGDILKAE
                     PEIGNESVTLTVKSDADITNLAPVFTLTPGATIKPASGTAFDFTTPRTYTVTSEDGHW
                     TKTYTVRCIVSGVSTEYHFEHITMEPKNERYQIFYDFTSNGDSVTWASGNAGFGLTGV
                     PKTPLDYPTMQDDNGYVGKCAKLVTRSTGSFGSGFGMPIAAGNLFIGTFDLLNAIPDA
                     RKGTRLGRPFDHVPTYLSGYYKYKAGESYKVNGEEVKGKKDQCDIYAIFYETDENVKY
                     LDGFNGLTSPNLISVARISDQKETDEWTRFYIPFVAKPGKVIDKDKLAKGGYQLSIVF
                     SSSLKGDVFEGAEGSTLWIDEVEIIQSGEN"
     gene            13110..14423
                     /locus_tag="ACZPB4_07090"
     CDS             13110..14423
                     /locus_tag="ACZPB4_07090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family protein"
                     /protein_id="HIR1098020.1"
                     /translation="MTTRRDFLRQTALLGAGLSISPFFIKAGSAGVGANDKIGVGLIG
                     CNGMGFEDLKAFLRNPEVECIALSDIDENVLNNRAAETEKITGKKVKHLYKDWRKLID
                     NKDIDLVIVGTPDHWHCLQMVSACQAGKDVYCEKPLGNSIEECNIMVRAAQKYNRVVQ
                     VGQWQRSDPHWQDAMQFVHSGQLGKIRTVRVFSYQGWCPSIPVKPDEAVPAGVDYDMW
                     LGPAPRRPFNRNRFHFTFRWFWDYAGGLMTDWGVHLLDYALYGMNVTAPESIMASGGK
                     FGYPDDACETPDLLQTIYTFKDFTVMWDHAIGIDDGAYGRNHGLGFVGENGTLVIDRS
                     GWEVIPEKVNGQARMEAVPLKNSYGEGGLNLHVKNHLECIKSRNRNCNASVEIGAHIA
                     KFSQLGNIAYRTGKKLSWDGKSFHDTEADKLLCKEYRAPWELPKI"
     gene            complement(14472..15992)
                     /locus_tag="ACZPB4_07095"
     CDS             complement(14472..15992)
                     /locus_tag="ACZPB4_07095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018666580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4301 family protein"
                     /protein_id="HIR1098021.1"
                     /translation="MLNANDLEQLKAKGISEKQIEEQLACFVKGFPFLEIAASASVEK
                     GIMVISKEEQASYMDAWDAYLAKNKKIVKFVPASGAASRMFKNLYEFLSADYKEPMNA
                     FEKKFFSEIEKFAFYKALDKKCVENTGKDIPALVALGEYKEVVSNLLEPKGLNYGQLP
                     KGLLLFHKYADTVRTAMEEHLAEGAMYAKNNAGEVNIHFTVSPEHQALFEQLVADKSG
                     EYEEKFSVKYDVSFSIQKPSTDTVAAAMDNTPFRDKNDKLLFRPGGHGALIENLNDVD
                     ADVVFIKNIDNVVPDSFKCSTVIYKKVIAGVLVTLQEKAFRYLEQIETGKYTHAEVEE
                     MIHFLQDDLCIKNPDTKLLEDAELILYIKSKLLRPLRVCGMVKNVGEPGGGPFLAENP
                     DGTVSLQVLESSQIDMSDPAKKAMFEQGTHFNPVDLVCAVKNYKGEKYNLPDYVDKNT
                     GFISYKSKDGRELKALELPGLWNGAMSDWNTVFVEVPIETFNPVKTVNDLLRPEHQ"
     gene            16168..18381
                     /locus_tag="ACZPB4_07100"
     CDS             16168..18381
                     /locus_tag="ACZPB4_07100"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008728 - GTP diphosphokinase activity
                     [Evidence IEA];
                     GO_function: GO:0008893 - guanosine-3',5'-bis(diphosphate)
                     3'-diphosphatase activity [Evidence IEA];
                     GO_process: GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RelA/SpoT family protein"
                     /protein_id="HIR1098022.1"
                     /translation="MDTIGFFTSEEKKLFFSKYRLLLRNLYSFLEREDIRKMKELMKR
                     VVALDCYGRDKNGINGLLRNIDTALIATLEIGLKRTSVIALLLYRPVLKKAITIEEVE
                     QKFGADVTLIIRRLLKTSDLYARNTAVNSENFHHLLFSFAEDVRVILLMIADRLCLMR
                     MGKQMQEDDRIRLATEASYLYAPLAHRLGLYTIKSELEDLSLKYTDRKQYDFIKRKLN
                     ETKRSRDAYIAEFIAPIKRKLAAAGFKFDIKGRTKSIHSINNKLKKQQVEFEGIYDLF
                     AIRIVLDTPLEKERSECWQVYSIVTDMYQPNPKRMKDWISIPKSNGYESLHITVMGPQ
                     NKWVEVQIRTRRMDEIAERGLAAHWKYKGVKAESGLDEFLNTVRAALEAKENNPLDLM
                     QDFKMDLYKDEIYVFTPTGELIKLAKGATVLDFAFAIHTKLGSKCVSAKVNGKNVPIK
                     YTLNNGDSVSVITSPAQSPKRDWLNFVVTSKARVKIKQALKEETVKAVEFAKEMLQRR
                     FKNRKIDMDEPTMMRYIKKKGFKTVTDFYIEIAEERLDPNQVIDEYLEAFRKETETNE
                     RTEVRSAEEFVTMTPVEEISTNKDVLVIDKNLTGIEYKLAKCCNPIYGDEVFGFVSTQ
                     GIKIHRMDCPNAQEMFSRFGYRIIRAKWSGKGDNGYTVTLRVIGRDDIAIVTNITSVI
                     GKESNVTLRSLNINSVDGLFQGNFTVLVRDTTALNLLTKKIKAVNGVKAVERLNS"
     gene            complement(18512..19942)
                     /locus_tag="ACZPB4_07105"
     CDS             complement(18512..19942)
                     /locus_tag="ACZPB4_07105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0052929 - ATP:3'-cytidine-cytidine-tRNA
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HIR1098023.1"
                     /translation="MYINEEEIVNHISAKPFHLISEAAEELGVEVYVIGGYVRDIFLN
                     RPSKDIDVVAVGSGIELAKRVAKKIGRGAYLSVFKNFGTAQVKAGDLELEFVGARKES
                     YSHDSRKPVVEDGTLEDDQNRRDFTINALALCLNKERYGELVDPFGGLEDMDELTIRT
                     PLDPDITFSDDPLRMMRAVRFATQLGFFIDPDTFDAIIRNRERISIISKERIVDELNK
                     IVLSPKPSIGFDLLDKCGLLPLIFPELCALKGVETKEGIGHKDNFAHTLMVLDRLSKT
                     SDNLWLRWSALFHDIAKPATKRFDPRLGWTFHNHNFIGERMIPGIFRKMKLPMNEKMK
                     YVQKMVSLHMRPIALSDDEVTDSAIRRLLFDAGDDIDDLMKLCEADITSKNPEKVRRF
                     LNNFRKVREKLADIEEKDRVRNFQPPVSGEEIMETFGLAPSKPVGVLKEAIKNAILDG
                     VIPNEYEAARQFLIQRAEKMGLKPIL"
     gene            20031..20855
                     /locus_tag="ACZPB4_07110"
     CDS             20031..20855
                     /locus_tag="ACZPB4_07110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098024.1"
                     /translation="MKKLAICITLIAAILTGCNGDEKAAQARLDKARAMYENNEFFGA
                     KNEIDSIRALYPKEVKVLKQGLTLMRQVEVKEAERNIAFCDSLLPIKLDEVEGLKKGF
                     AFEKDSVYEEIGNYIWKQQTIERNVQRCYVRCGVNEEGEMYLASVYYGGRPIEHTGIK
                     LSLKDGQFAETASIPYDGGLNYRFKDMGSTTEVVTYKGEHCVDAVKFIYDNEKERIKV
                     EYTGGKPYIIYMADADKKAIVNTFNLATVLSDIKSMNTLKEKSEKKIAYLKNKLEE"
     gene            complement(20964..23618)
                     /locus_tag="ACZPB4_07115"
     CDS             complement(20964..23618)
                     /locus_tag="ACZPB4_07115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6383 domain-containing protein"
                     /protein_id="HIR1098025.1"
                     /translation="MDKKCTLIAAALMVAGVFSANAQSSTTVPEAQWKAGNYYYLKTG
                     SSVLSLSGEKADSVIVKTLASDATKAAIDSALWQITNAGTTPAGPVYQFKNKKTQAVL
                     SFAASSTAKPVITSGVNQWTFSDAAGGSAIQAYYGNNQILALDVAGTDLSLGSSASST
                     KFTVEAPSDAMYLSASELGDGFQVFQLTFGGNYQGNIFEGKNLIAKNTAAPTTGAVAN
                     AKYVTLQIQGDQVFSDGKAKYLGVDTLKNVIAGATGVYGAKFTADSTYDASGLHTLGN
                     ADFQKFYFTINLKNDALAMYAAAAPTVNASPMTSVPNVRVVYASVIETKALTVSDLQS
                     GSTQPAQGAAPVITVTKGTPSTIATGTGVYFLKSASKGDKGGQYAVAYDKSAASDKLV
                     TAAGFKPSIYQPKGQWYIKENNGMYSVVDRNTNTTIISNEEIFAVQGMANTYTFGGST
                     DSITVEYQANVDLKDKFLGTRHFSAEELADNGYVLNLISGTPGVDDLYAFTSDSVLMI
                     KSGDAANAAALRIVVSQDSVQNVTDGLGARALGDTLYHATYMLKERFSNDLVASENGG
                     PLKLSDYTAPLEFVFNTATTGGKYQMATRVGATTQYVFMNVNTANLILSDKVNYFDFV
                     AVEAPEYASIDNSHKRFGTNGKFLTMNPLNFFAEVKNEGQDILKSTYETDNFSLWVQE
                     ADTVIAGKPLYFITTSIYTPETTTKAVSPRYYMVSLRDSNETFVSNGATYYRVGFSDK
                     ANIVPSLDNNALFAFKTTQDGGYLLENQKELNRTVAAGELKTPYVGVVNNVVVMSNVG
                     VPFTIENAPTPVSNEQLEEVASFTVIAGEASVTVLNAAGKTVTLSNILGQTTASAIAS
                     SDNFVMPASKGIVVVSVDGETAQKVVVK"
     gene            complement(23885..24214)
                     /locus_tag="ACZPB4_07120"
     CDS             complement(23885..24214)
                     /locus_tag="ACZPB4_07120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098026.1"
                     /translation="MKKIVYGVIVALCGLFIAPDVEAQAGMVGSAKETVAQDKFYPIE
                     VTDMPQVLRDAVNTSYEGCMVKSVEVSNNSTFVKYKVVLLSRNGKIYKVYFDDRGHVV
                     KEHAYFE"
     gene            complement(24707..25552)
                     /locus_tag="ACZPB4_07125"
     CDS             complement(24707..25552)
                     /locus_tag="ACZPB4_07125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HIR1098027.1"
                     /translation="MVLLAAVEASSKLEEAIRSLVEHGSQLGFTIIKALIVFLVGRLV
                     INLLNKLVRKILSKRDIDPSVKTFVGSLVNVSLTILLIISVVGALGVQTTSFAALLAS
                     AGVAVGMALSGNLSNFAGGLIILLFKPYKVGDYIEAQGVGGTVKEVQMFHTVLGTVDN
                     KVIYIPNGSLSSGVVTNFSNQTTRRVDWTFGVEYGSDYEKVKQVIESVLAKDSRILSE
                     PAAPFIALTALADSSVNVVVRVWVNSSDYWGVYFDINKNIYATFNEVGIGFPFPQLTV
                     HQAKD"
     gene            25711..26532
                     /locus_tag="ACZPB4_07130"
     CDS             25711..26532
                     /locus_tag="ACZPB4_07130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HIR1098028.1"
                     /translation="MKILAILAALFLSIGYGHAQTYEKFVEKSFDFLDKNDLVSAEES
                     LRAAMRLEPGNPNNYALLMNLGTIQRRQGKLEDALLSYTAALSRHPNNEAILENRAGL
                     YTEMGEIEKATNDYNALLILNPHHQEALYCRAMLHLQHKNYLLAEQDFDKILEVNEKS
                     VKGRLGHAILEKLRGNYDESERIFNYLISEMPREWILYEGRADLYFMMGKNARAMADI
                     NRVFVESTPTAALYVLRGKVKLAQYEKASAALDFKKAEDMGYDKTTIDELMKMAR"
     gene            complement(26665..27726)
                     /gene="leuB"
                     /locus_tag="ACZPB4_07135"
     CDS             complement(26665..27726)
                     /gene="leuB"
                     /locus_tag="ACZPB4_07135"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003862 - 3-isopropylmalate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HIR1098029.1"
                     /translation="MKLNIAVLPGDGIGPEISVQGVEVMSAVCEKFGHEVHYEYALCG
                     ADAIDKVGDPFPEETYRICKDADAVLFSAVGDPKFDNDPTAKVRPEQGLLAMRKKLGL
                     FANIRPVQTFKCLLHKSPLRAELVDGADFLCIRELTGGMYFGKKYQDNDKAYDTNMYT
                     RPEIERILKVGFEYAMKRNKHLTVVDKANVLASSRLWRQIAQEMAPSYPEVTTDYMYV
                     DNAAMRMIQEPKFFDVMVTENTFGDILTDEGSCISGSMGLLPSASTGESTPVFEPIHG
                     SWPQAKGLNIANPLAQILSVAMLFEYFDLKEEGALIREAVDASLDANVRTPEIQVEGG
                     AKYGTKEVGSWIVNYITEK"
     gene            complement(27742..28185)
                     /locus_tag="ACZPB4_07140"
     CDS             complement(27742..28185)
                     /locus_tag="ACZPB4_07140"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008929 - methylglyoxal synthase activity
                     [Evidence IEA];
                     GO_process: GO:0019242 - methylglyoxal biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HIR1098030.1"
                     /translation="MKKLTIALVAHDNRKAEMVEWAVHNAEFLSHHHIVCTGTTGNLV
                     RKALEEKGVNADIACMHSGPMGGDAEIAAMVVRKEIDLAVFLIDDLNPQPHEADIQML
                     LRQCRVHNVPIACNRYSADLMITSTLWDDDTYFPTEPKYVHFNRE"
     gene            complement(28206..29720)
                     /locus_tag="ACZPB4_07145"
     CDS             complement(28206..29720)
                     /locus_tag="ACZPB4_07145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003852 - 2-isopropylmalate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-isopropylmalate synthase regulatory
                     domain-containing protein"
                     /protein_id="HIR1098031.1"
                     /translation="MIEIMDTTLRDGEQTSGVSFAAHEKLSIAQVLLSDLGVNRVEIA
                     SARVSDGEFEAVKRVAAWAARSGNLDKLEVLGFVDGTVSLDWIESAGCRVVNLLCKGS
                     YKHVTEQLRKTPEQHVDDIRTVVLEAAKRKIDVNIYLEDWSNGIKHSPDYVFLVIDAL
                     KGLPICRFMLPDTLGVLNPGNTYEYCKMMVDRYPDLRFDFHAHNDYDLAVANVYSAIR
                     AGIKGIHTTVNGLGERAGNAPLSSVLAVIKDQLGEETSLREEKINKASRLVETYSGVH
                     IPPNKPIIGEHVFTQCAGVHADGDSKNNLYCNDLLPERFGRVREYALGKTSGKANIRK
                     NLEALGIDMDEGSMRKVTERIIELGDKKEMVTPEDLPYIISDVLHHDNALEDQKIRIL
                     NYSLSLAQGLKPVATLKIEINGEAYEESASGDGQYDAFVRALRRIYSRLNRPFPMLTN
                     YSVSIPPGGRTDAFVQTVISWNYAGVDFKTRGLDADQTEAAIKATLKMLNKIED"
     gene            complement(29723..30310)
                     /gene="leuD"
                     /locus_tag="ACZPB4_07150"
     CDS             complement(29723..30310)
                     /gene="leuD"
                     /locus_tag="ACZPB4_07150"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009316 - 3-isopropylmalate dehydratase
                     complex [Evidence IEA];
                     GO_function: GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HIR1098032.1"
                     /translation="MKTKFNIITSTCVPLPLENVDTDQIIPARFLKATTKEGFGENLF
                     RDWRYDKEGNKIESFVLNDPTYSGKILVAGKNFGSGSSREHAAWAIADYGFRVVVSSF
                     FADIHKNNELNNFVLPVVVTEEFLAELFDSIYKDPKTEVEVNLPEQTITNKATGKSEH
                     FEINAYKKDCLINGLDDIDYLLANKSKIEAFEAAR"
     gene            complement(30337..31734)
                     /gene="leuC"
                     /locus_tag="ACZPB4_07155"
     CDS             complement(30337..31734)
                     /gene="leuC"
                     /locus_tag="ACZPB4_07155"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009316 - 3-isopropylmalate dehydratase
                     complex [Evidence IEA];
                     GO_function: GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="HIR1098033.1"
                     /translation="MSKTLFEKIWDKHVVDTLPDGTIQLYIDRLYCHEVTSPQAFAGL
                     RARGLKPFRPAQITCMPDHNIPTLNQDKPIEDPISKNQVDTLEENAKYFGLTYYGLQH
                     PKNGIIHVVGPETGLTQPGMTIVCGDSHTSTHGAMGAIAFGIGTSEVEMTLATQCIMQ
                     RKPKTMRITIDGVRKPGVTAKDFALYIISKMSTSGATGYFVEYAGEAIRNTTMEERLT
                     ICNLSIEMGARGGMIAPDDVTFDYLKDREFAPRGEEWERKVSEWRQLYSDPDAKFDKE
                     IVFHAEDIDPMVTYGTNPGMGMSISKDIPSLESVPEAGRISYKKSLDYMGFKAGESML
                     GKKVDYVFLGSCTNGRIEDFRAFASLVKGKKKADDVTVWLVPGSWQVEREIRAEGIDK
                     VLAEAGFVLRQPGCSACLAMNEDKVPAGKYAVSTSNRNFEGRQGPGARTILAGPLVAA
                     AAAVTGKITDPRELM"
     gene            complement(31749..33251)
                     /locus_tag="ACZPB4_07160"
     CDS             complement(31749..33251)
                     /locus_tag="ACZPB4_07160"
                     /EC_number="2.3.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003852 - 2-isopropylmalate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019752 - carboxylic acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HIR1098034.1"
                     /translation="MSDRLFIFDTTLRDGEQVPGCQLNTVEKIQVAKALEQLGVDVIE
                     AGFPVSSPGDFKSVVEISKAVTWPTICALTRAVEKDIDVAAEALKFAKRGRIHTGIGT
                     SDSHIKYKFNSTREEIIERAIAATKYAKKYVEDVEFYCEDAGRTDNEYLARVVEAVIK
                     AGATVVNIPDTTGYCLPDEYGAKIKYLMEHVDGVHNAILSTHCHNDLGMATANTVQGV
                     LNGARQVEVTINGIGERAGNTSLEEVAMVFKSHKERDIITNITTNKIYSTSRMVSSLM
                     NMPVQPNKAIVGRNAFAHSSGIHQDGVLKNAQTYEIIDPKDVGIDDNAIVLTARSGRA
                     ALKHRLHVLGVDLEQEKLDKVYDEFLKLADRKKDINDDDVLMLVGKDRTATHRIKLEY
                     LQVTSGVGVQSVASICLNLSGVRKYEAAAGNGPVDAGIKAVKKAISNSDMTIQEFLIQ
                     AINKGSDDTGKVHMQVEYNGATYYGFSANTDIIAASVEAFVDAINKFIVD"
     gene            33934..34167
                     /locus_tag="ACZPB4_07165"
     CDS             33934..34167
                     /locus_tag="ACZPB4_07165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098035.1"
                     /translation="MTKLSNIPAKETTAKTAKTRKAKTEPAKPKWDPTKPMQFTQEEI
                     REHIHEIEKGPFYPIEEVHQRIRSWMDSYQGKK"
     gene            34137..34478
                     /locus_tag="ACZPB4_07170"
     CDS             34137..34478
                     /locus_tag="ACZPB4_07170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0090729 - toxin activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HIR1098036.1"
                     /translation="MDGQLSRKKVIGSPIYEESLERTFVEGIERFGMFQARKYLEHIL
                     NTVEKLENDYPYYPECRHLTTKSRMYRNIILDSHLIIYRITEERIEVLDIFHSASSMR
                     KIKKTKNIHIE"
     gene            complement(34548..>34679)
                     /locus_tag="ACZPB4_07175"
     CDS             complement(34548..>34679)
                     /locus_tag="ACZPB4_07175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HIR1098037.1"
                     /translation="QISIDSNSKPDYREKLEAELKALRESEMWQTAVTVRKLRPENN"
BASE COUNT         9635 a         8706 c         7366 g         8972 t
ORIGIN      
        1 aatgagtgat caactttcaa aaacaacaag aatgaatacc caaagtgaaa tttattttgc
       61 cggtggatgt ttctggggaa cagaacattt catgaagcaa atcgatggcg ttacgaatac
      121 ccgagtaggt tacgcaaacg ggaagatgag tatcaaaaac ccgacttacg aacaagtgtg
      181 taacgataat accggattcg cagagactgt ggaagttagc tacgatccgc gacaagccga
      241 tttgaagtta ttgatcgaac tattcttcaa gacgatagat ccgacaagta tcaaccggca
      301 aggcaacgat atcggatcac agtatcgtac cggcatctat tatacgaata cggacgatct
      361 gccgatcatc aaagagaccg tggaggcatt ggccaagaat tataccaagc ccatcgtcgt
      421 agagattcag ccattaagta atttctatcc ggcagaagac tatcatcagg attatttaga
      481 taaacacccg gacggttatt gccacataag cccggatcta ttcgatttcg cccgaaaggc
      541 taataagggg aaagcctcga acaagcctgt atcgcaaaag aaattccaga aaacggatga
      601 tcagacattg cgctctaaac tcaccgccga gcaatatgcg gtaacacagc aaaacgctac
      661 ggaaagagct ttcaagaatg aatattggaa tgaaaagcgt gaaggcatct acgtagatat
      721 cacgaccggg gaacctttgt ttatctctac cgataagttt gattcgggtt gcggatggcc
      781 tagtttctcc aagccgatag acaagagctt ggtgatggaa aaaacggatc tttcccacgg
      841 gatgaaacgg attgagatac gcagcaaaac aggagatgca catctagggc acgtttttaa
      901 tgatggccca gccgacaaag gtgggttacg atactgcatc aacagcgcat cattaagatt
      961 tatccctaaa gcaaagatgg aagaagaggg atatgccgac tatctcccac tcctataaaa
     1021 acaaataaaa aaacatagtt atgatctgtt caactcataa ctatgttttg aaaatttcat
     1081 aactatgatt ttttaatagt atcttcgccg tataaaacaa gcgaaagaag cactatgtat
     1141 cacgaattta ccccctgcgc agccttagcg ccctttatcg acaagttctg ggtgttcaaa
     1201 ggctttaccg acatcgggac acgttttaag atcctcgcgg acggatgcac cgactttatc
     1261 ttctcaatcg gtaacatgac cgtccctacg gacgagcatt cgatgatcat gcaaccttat
     1321 cgttcctatt tcgttggtcc tatgcgggtt tattcggatc tgactgccac gacaaatacc
     1381 ctgcacatgc tgggggtccg ttttcaaccc tgtggattgg ccgctttcac gaatgagcct
     1441 ttgggacagt ttgccgatct tcgcatccag tcttcagata ttaacctttt attcgataat
     1501 gcctttgccg agatgctttg cgaacagccg gacgattccg tccgtatccg cattatcgaa
     1561 ggctatctta tacgccttct cacccaatcc attcaagtag acagacaaat tatatacgcc
     1621 acctcattta taaaacagtc tcgcggacag ctacccgtac aaaacttgat cgacaagatt
     1681 tgcatttgcc agcggcattt ccaacgtaag ttcaaggatg ccaccggata tactcccaaa
     1741 gaattcagcc ggatcataaa attccaatat gccatagaag tactgaggaa cgccccacac
     1801 acggacttaa gcagcatcgc cttagattgc ggctactatg accattccca ctttatcaaa
     1861 gaattcaagc gtttagcggg agacgttccc tcttacttcc tgactttacc aaatcctacg
     1921 gatgaaccgc ttacttatat ttgattaaaa ataaaatcgc aagaatctat cacataaaaa
     1981 gtcgtttttt tacaaccaga aagaatagtc attccgtatg tttgcactat tgaactttta
     2041 caaataagaa tcttatgaat tacacttttg aactaaaaga actacaagct acacacatcg
     2101 tgtatcttca tcatcaagga gatatgagct tgatcccaag ctctatcaga aagcttatgc
     2161 aatgggcagg gccaaaagga cttataaacg gtccggcaaa taaacttata tcagtttacc
     2221 aacacgaagg aaaggagtta agtgtggata tcggtttaac agtgcctcaa gaggtagagg
     2281 gagaaagtga gatctcaaaa ggattattat ccggaggact ttacgcaatc gggcattttg
     2341 agataggaac ggatgaaata cccgccgcat ggagcttgat gtacacgctt acatccaaac
     2401 accaatgcaa gccttgtgcg ggcaaatcat tcgagatcta tcaaagcatc cccctcgatc
     2461 aacatccaca agataaatgt atgatcgatt tatgtatacc cgtccagatg atagacctca
     2521 agctaatcga ggaaaaagca atttccatat taacggaatg tgacaccgct atgcttgcgt
     2581 ctgttacgga agatggttat ccccgtccgg ttcctatggg aaaaataaaa gcggatggta
     2641 tttcccaaat atggttctct acaggcacgt tctctgataa gacgatacaa ttccaactca
     2701 acccgaaagc cggagtttgc tttatgaaag gaggagacag tatcgtgtta acaggtaagg
     2761 tcgagatcgt ttccgatatg gaaatcaaga aagccctttg gtctgactgg atgttcgctc
     2821 atttccctgg aggagtaata gatccgagct attgtatatt gaaattcact tccgaagaag
     2881 cgacttattg gatcgataat gaatttgtaa aagcaagtat ataagttatc acatcataca
     2941 atcgcatcta aaatattaaa aatcttgatt gccgctaatt agacaagacg gcaatcaaga
     3001 ttaattcatt tattcacttc agaaacctct ctagctctta ttattctacc gccacataaa
     3061 tctgagtcaa taaatcctcc ggcttcgtat tacgaggatc attcaagtag atctcgccgc
     3121 taggcacttc ccgtaaggaa agacccatct cggggagata tttaccgtaa agcgtatcat
     3181 acacagcccc taattgctga taagttccct tataaagagc gaccataaaa cggccttcca
     3241 ataccttttt cgtaccaatc tcccctttag gacaaactga aggagcgact tccatacaaa
     3301 tatcggtacg cagcttatcc ggcgaggtta ctttcgggtc gtcatggtac aagcagatcg
     3361 gtgaaaaact caatggctgg atgttttgct ccttagcaaa ttggagcaag cgcatccaag
     3421 ttcccggata atcgatttct ttataccctc cgtttaaacg aatgtaggct acttgtttac
     3481 cgggtaaatc ttttacctcg accttcaatt ccatatcggg cattattcta ttcggttcca
     3541 taattacata atctttattg tttctatatt catttggaga aataccatag aactggcgaa
     3601 aaaccttaga caaagaagag ggtacgtcat atcctacttt ataagcgatc tccttgacag
     3661 gtatttccgt gtaacgcaaa agccgagcgg ccgtctcgac ccgcatccta acgataaacg
     3721 taccgaccgg ttcccctaag aattccgcga agatccgata aaaatgccaa cgagagaatc
     3781 cggatatctc cgccagctta tttagatcga catcctcgcc taagtgatta tttatgtatt
     3841 caaccaatac attgatacgt tgttgatact ctgtctttgt cgttgtcttt attcgcatga
     3901 ttcttagaat ttcaaggcaa aagtagaaga attatcccga acacactttt ccgatattgc
     3961 taaaatgaac tataaagtaa agatatcgtt tatttagccc aaatccgtta tctttaccat
     4021 ctaaattaaa ataggaaaca ataacatgtt gaaaataaca gcgcctagat tggtaaaaaa
     4081 cttacgggag gatgtggact ggatggattg tatatccaga caagaggatg attttacaga
     4141 atgctctttc aatggattat gcgtcgagga cgtatctaaa cagaacctat ccgttaattc
     4201 ctgcttattc accaattgtg gtttcattgc ttgcaattat cgtaaatctc agtttagcga
     4261 tgtggtattt aagaactgtg acctatcaaa tataaattta tccggatgtg gcttttaccg
     4321 ggtagagttc attgggtgta aacttaccgg aacgaatttc tccgaatcaa tctttaatca
     4381 tactaccatc cgggattgca aaggagatta tgtaatcttc tccatgagca aactccggaa
     4441 cgtttctttt aatcaatgct ttttacgagg gggcggattg gacaattgcc aatttacgaa
     4501 cgttgaattc gaacattgta atttagtaga ggcggagctt caccggacct ctttgaaagg
     4561 gatcgatctt acttcctccg agatcgccgg tatacgtatt ggctcgattc ccggaggaga
     4621 gttgaaaggt gctaccgtaa cctccttaca agcactggac atcgctagaa tgttaggcat
     4681 tacgatcaag gattaaaact ccggatggcg ttttaaccac acaaccgcat aggaacaggt
     4741 agccaaaggg cgcaacccct gttccttcgc gtatttataa gctgtttcaa caagagtcgc
     4801 cgcaatccca cgcccttcca agggttttgg gacaatggta tggataatgt ccaaggcatc
     4861 tcctcttaaa cgatattcca cataggctgt caagccgtct tctactacct cgaaacgatg
     4921 tttatccgga tagtgattta ctgtatattc cattatttat tcttttaaag gttctatttc
     4981 cttattattt gtatcaatct cctcccgctt atccttcttt ttatcgagac cgaaaaagcg
     5041 ctttaccttc gtgaagaaac ctgccacttt caaggccgca tcctgttctt ttttcgagac
     5101 tccgactgat tccaccaagg ctggtcttag catctgccat agatagttga acgtggaatg
     5161 atagggatct cgcacgattt ccatatcgac cttacgtaat ttactatctt tccgctcagg
     5221 atgggccgga ttattatccc gtaagaccaa gttcgccaat ctcgacaaga aacctttttg
     5281 tgtggtctct ccgtctttct ctttcaatag ggccactttc agtttccgat acgggaagtc
     5341 taaccgtatc cggcctttcc ggcttgaggc atccatatga aagaccacat cctgtgccca
     5401 accgctcact acttctgccg gcgccagagg ttttatgatc tcatttaagg aaagcaagtc
     5461 taggctatcc aaacaggcat ccaatagaaa gcggtcatat aatgaatcca cggggagttg
     5521 ccatgtagcc gtgaaatgcc ccgatcccat caggttcccg tccgcatgca atctgatgaa
     5581 ttgctccgga taggaaacga tattggtcaa tcctgagaat tggccgttca tatcggtaaa
     5641 ataaagctta ccgggtttgt cacctttaac gggcaattcc tcataaacca cggagaaatt
     5701 ggcaatggaa gccgtatcta tcttgaaacg gaccggagcc ttttgcaaac cctcataaat
     5761 catcgggacg atatgaggct ccaccgggat cttccggttc tttaagtttt gtaataagac
     5821 atcgtttatc cagagccctc ccacatgtaa ttccttggtt gagaaatatc cgggaatatc
     5881 cacgtcggtc aatctcacgt tcccaacctt cacgtcaaac caatcttgat gcttaggctg
     5941 tttataagcg aattccattt tagaataagg cgagactaaa tgtacgtgat ccaacctcaa
     6001 acctgactct ctcaaatcca gccccccgat tttcaaacgg tagaagccgt tatccaacgg
     6061 tatatcgata tccttcgtct gtagctgaag atcacctaat tgaaacgtct tcttcttcaa
     6121 atccacaaac acattctcca aagccaattg gatatccttt tggctctcag tccgcaatat
     6181 tgtcgtatcc gatccccaag acatagaaaa atcaccatcg gataaatcaa atcggtcaaa
     6241 cccgatctga tagatgctat tcttgggaat ccggattccc gttaaagaaa tcaatggggt
     6301 tgaaaaacgt atcgagtcct ttttagcggc cagggtcaca tcctgtagac ggaaagagcc
     6361 gtttacggtg gatagcgaac cttttcttat agtcacacgc agatcctttc ccggtaagta
     6421 gttatcgaaa tcccggaaac taagaccaaa atgatcatac ttgaaaaaca attgcccact
     6481 ccggttcgtt tgctcatcca ccaagaaatt cgtagcaaag aaattaaggc cgttgagtcg
     6541 gtaccgggtc gtgtcattta tctcacgatc ctccaatgtc acatttgcgt tctgaatctg
     6601 gatcttacgg atggaaagat accgaaggaa aggatttaac aaactctcca catccacacg
     6661 gctatttaca gatgtgcttt tccctttatc cggagattca acggagggcg ttttataata
     6721 aaccaagcga ggcgaccgaa ccttcagtaa atctgcgcta acacctttgt cgtacgccaa
     6781 cccgtctatc cggatcgtat cgatacttcc cgacaaataa tcattacggg agcggaccga
     6841 caacggacgt agtcgcatgc tatctatatg aaacgagcct aaggccgtat tcatcgccaa
     6901 acgcttaata tcgaaccgat gattacgagc cctcatgatc ccttgtatat cattcgcctc
     6961 aaacgcaatg gaacgaaaat aattcagttc ctcgcccgga gctaccaagg agtcgatcag
     7021 aagaccttcc gcatggaaat taaactcagg gatcgagaag tcctctatct gccctttcaa
     7081 ggctaaggaa tagtgaagtg cggttcgctc tattcgtatt tgatccacgg atatactatg
     7141 tagtaccgga gagatcacat catataacga taaggcttgc accaaagaat ccgcatcggc
     7201 attcgcctgc ttcttctccc gagtcaagtc atacacctta atatccgaag attgtatctc
     7261 aaaattacgg gcggacaaat agttcaaggc ttcttcccgt ctaaagtgaa tcccttgtat
     7321 ctctacggtt tgtaccttcc cttccagata attcgttggt ttccgattgg tctcccccca
     7381 caataattct tgcggaagca attggatttt ttggatatag ataatggaat cttgggtact
     7441 gaggcatata ctatccgtct ccaacctaaa atcattattt accaacaagg tttgcggctg
     7501 gttcgtgaca aaatcgaagt tatcgcaata caacagcttc ccgctccgtg aagaggtaga
     7561 atccaacata aaaccatacg catggaaact tacgttattc aacgtataga taatcggcga
     7621 gacttggttt tccacattat aagagatact ggcattttcc aagttcaagg tctttacgct
     7681 cagggcatct atgtatggag agatcacctc gtacaaggtc ttcgattcgg catgctctac
     7741 cgtatctgcc gccagtccgg aaactaacgg gtttgatccg gaagagccgt atacacgaac
     7801 ctccggcgag cggatctcaa aggtattgaa atggagttgc cggtaattcc atcgccatac
     7861 caaattaatt cccttaaaat ctatcacctc aatccgggta cttacatagg tatcgggcaa
     7921 gctatccaag gcggcccaat gttcaaagac cttagagtcc ggctccaatg aaataccctc
     7981 tagccttagc tctcccttga agaagctaat agaaagctta tcgaaagaaa ggcgataaaa
     8041 accatccgta gcattcgccg tacgctctat cagttctctt ttcaggtacc gctccaaacg
     8101 acctgtcagg aaaagattca aaactaggaa caatacagcc agcgataaaa cagcgatcac
     8161 cgtatgtttc aatatcttcc ttatcctaga actcatcctt tccttgattt ttgcgatata
     8221 aacttctttt tataaaaaca aaatagaccc gtttatgttg cctttcatct aataaaaaag
     8281 ccccggagtc tattaacccc gaggcttacg atctatcgat tgttacttca ttttacaaaa
     8341 ggagccttga tcaaatagtc ggcgcaatcc ttcacacccg caaattgagt acgtccgtcc
     8401 ggcatctgct ccaactctac gaaatagtct ttgattccgt ttgcgtacat ttgcttgaat
     8461 atcatctcaa agttcatcat accactttgg ccgaatacag cacgatcctt gatatgtaat
     8521 accttgatac gatccggatg tttctgcata tactcgacag gatcgttttg tcccatgaca
     8581 gtccaataaa catccatctc gaagtaaacc ttgctcgggt ccgtatcttt cagcatcaag
     8641 tcataaattt ggtctccgac tttcatgaaa gcggcgaaag gatttccttt caccttctcc
     8701 tgttgctctt tcgtcgcgac ccgattgaac tccatattat gattatgata gccaaaacca
     8761 gtggcgatac cctccgcctt gataacatcc gaggcctgat tgaaaatatc gcaaacaagt
     8821 ttagcctcat cgtgcgtagt aatcgtcggc atcatcggct ggatcaaata tttacagcct
     8881 agtttcgcat gatcggcagc cgtagctttc caatactcca tgatctttgg ggtaacctcc
     8941 ttcgagtatt tgaaaatcat agccttaaaa gggtcagaaa tagatgtgtc taccggattc
     9001 acgtgcgagc taatgatctt caagccagcg tcttccgcca ttttcttgaa gtccatcata
     9061 ggaacacccc cgatagcgcc tttaccataa cccgccaact ccagcttgga gtatcccata
     9121 tccttcacct tccgaagatt agcggccacg tcacctttat ataattcttg ggataaagaa
     9181 tagatctgca agccaatctc tttgctggca tggacctcat ccacaactcc caacgcagcg
     9241 ttcgccgcat ttacggaacc ggctttacca gccagcaatc caccagcggt aaagagagag
     9301 atatttttta agaaatcccg tctgttactc ataacatcat tctatttaaa taggcttatt
     9361 tacagaaata aggcaatgaa tacgggttgc gatattgata ccagtacaaa cggtgggaag
     9421 ccgcctcctt atcattaccg aagcttaatg tagccgggtt ccatttaacc ggacggccta
     9481 gctcacgggc aatattctgt aaacagcaaa gcgtattcgt actgcaacct acctcaaccg
     9541 gtgcgatcgg attctcacgt gaacgaacgc agtcgatgaa gttctgcata tgcggagcac
     9601 tagtctcata attacccgca tcgttaccct tctttttgct gtctttcagc ttcttcatat
     9661 attcctcata catcttctta cgctcttccg gagtcatcat tctcgggcgc ttctcgatca
     9721 agttcttcag gtcggagggg atcttagact gatcagagca gttgatgtag ccacgagcta
     9781 cctcgatcca accgttatca ccgacaaact taataccctg cgcatccgga ttatcctcca
     9841 aataaggttg ttcagtcatt acgataccat tcgcatagcg catggttgaa tattgcgtgc
     9901 cattgtatcc cttaggtgta aactcaaccg gaccagagcc atccataccg atagcggctt
     9961 gggcgatatc gaacatatga gcgccccagt cagcggtata accattacca gtctcttgat
    10021 accaacgcca tgcgccccat agtttctcgt tctcttccgg atccagagaa ataggaggac
    10081 ataaatcggg atgataatgg atcttcggat cgttcaacgg acccatccac tgattgaagt
    10141 tcaaattagc gggaaccggc atttccggca agctcagcgg cgtaggaggc tcacctacac
    10201 gtgcatatat tttctctata tgaccgatag ctccattctg aaccatatcg atcgcagctt
    10261 ggaactctct gctggaacgt tgctgactac ctacttgaag cacacgttta ttattacgta
    10321 cggcttttac catagccaaa ccttcagcga tcgtataagc caacggtttc tgacaatata
    10381 cgtcttttcc agattgacaa gaatgaatgg tagccaaggc atgccagtgg tccggggtag
    10441 cgacctcgat agcgtcgata tccttacgct ccagcaaatc ctcgtaaaac tcatattgat
    10501 cacaacgttg gttcattccc tttgaggctt gccattcagc gacacgtctt ctgaaacgct
    10561 ctgttttcat cgtgtccacg tcacaacatg cggcaacctg tacgcccgga catgcggcaa
    10621 atcctttaaa gtctgataat gcttgctgac ctaggccgat aaaacctaaa acgactcgat
    10681 cgctcggggc gatacggact ccatcaatgg cccaactggg aagaattgtt aaactagcca
    10741 atcctagtgc ggaaagaccc aaaaactctc tacggcttac gcccttctta gtgttttctt
    10801 tcatggtaat tttgttaata atataagata aaatgtaact tggtctgaga atgattgccc
    10861 caaagttata aaaaataatt tatttccata ataatctttt aataaaaaag gctatccttg
    10921 tccgggatag ccttattttg attcatatca attcctaaaa cgcatatccg aagcctacgt
    10981 tcagatagat cggatacatc ccgaaggtaa tcgtatcgaa atccttttgg aagatatcgt
    11041 tcaatcccca tgtcaagtca gcgtatacga taaggtgctt aaacgctttc cattctgtac
    11101 cgatctgcgc tccccactga aactttctta agttatccga gaaatcatag gaagcacggt
    11161 tgtcaccaga aaactccacc ttcgtaccgg taggattgat ctcacgcaga tatccgtcgt
    11221 atacgtagcc ggagaagttc cggtttgtag cgaacgagac aaatggtccc gccgagaaac
    11281 tcacccggtt attcaattgg taaagagcca cgaccggtat cgagaaataa gagttctcca
    11341 ctttcgtctg cacgccgccg gtccagtttc ctttcagctt ctcgccaccg gagccaatga
    11401 tctccatgct gtaattctta accgtcgctt ttgtctccat acctttattc tccagacgga
    11461 gaccgatcat cataccccat tccttgctct cgccgaacca tttcttgata tcgccctcta
    11521 tggagacaca aagcgtaggg cgataactat ctatcgcacg aatctcacga ggcaatggca
    11581 ccggagcggt tccgccgata ttgataccgg cctttaccgt atattccaat ccccttaggg
    11641 aagaccagat tattccttgg tttctttcct gctgcgcctt caacgtaatg acacccgaca
    11701 agcacagtat acctattaat actatatatc ttttcatatc ctctgttttt ttagttctca
    11761 ccggactgga ttatctcaac ctcatcgatc caaagcgtgc taccttccgc tccctcgaag
    11821 acatcacctt tcaaactcga agagaagact atggataact gataaccacc tttcgccagc
    11881 ttatccttat cgatcacctt accgggctta gccacgaacg ggatatagaa acgcgtccac
    11941 tcatccgtct ctttctgatc gctgatccgg gcaacggata tcaggttcgg gcttgtcaac
    12001 ccgttgaaac catccaaata tttcacattc tcatccgtct catagaagat ggcgtagata
    12061 tcacattggt ctttcttacc ttttacctcc tcgccattca ctttatacga ctctcccgct
    12121 ttatatttat aataaccact caagtaagtc ggcacatgat cgaaaggacg tcccaatctc
    12181 gtgcctttcc ttgcgtccgg aatagcgttc agcaaatcaa acgtaccgat gaaaaggttt
    12241 ccggcggcga taggcatacc gaatccgcta ccgaaactac ccgtgctgcg ggtcaccaac
    12301 ttagcgcatt taccgacata tccgttatcg tcttgcatgg tgggataatc caacggagtc
    12361 ttgggcacac ccgtcaagcc aaaaccggcg ttaccactcg cccatgtcac ggaatctcca
    12421 ttcgacgtga aatcatagaa tatctgataa cgttcattct tcggctccat cgttatatgc
    12481 tcgaaatgat attccgtgct cacaccagag acgatgcaac gtaccgtata ggtcttcgtc
    12541 caatggccat cctcggaagt aaccgtatag gttctcggtg tcgtaaaatc aaaagcggtg
    12601 ccactagccg gcttgatagt agcgccggga gtcaaggtga ataccggagc taggtttgta
    12661 atatccgcgt cacttttcac ggtcagcgtc acggactcgt tgccgatctc cggctcggct
    12721 ttcaatatat cgccatctac cgtacacgat aagatatccg cttccgcatt gggcgcctcc
    12781 tcccggatac aagagacgga gagtaacgtc aataaaaagc ataaaacaaa actttgtacc
    12841 ttcatacttc aaaatcttta taattcatat tgaaaaagga tcacacctcc ctattattca
    12901 tataggtctc tttcaagtac ctataacggg gaacaaaggt aatctattat gcgatacgta
    12961 gtattcctat atattttaat aacttttttt acaatgccct tttctcacac ctacggaaat
    13021 gacgagattc caagagaatg aggtttatat atttgcgatt gtcataaaat actactaata
    13081 tcgcgtatac ttaaatctgt atagaccata tgacaacacg aagagatttc ctccggcaga
    13141 ccgccttgct cggtgccgga ctttccatca gtcctttttt cattaaagct gggagtgccg
    13201 gtgtgggcgc aaacgacaag ataggcgtcg ggcttatcgg atgtaacggc atgggattcg
    13261 aagaccttaa agcgttcctt cgtaatccgg aagtagagtg tatcgcctta tcggatatcg
    13321 atgagaacgt attaaacaac cgggcggcag agaccgagaa gatcaccgga aagaaagtga
    13381 agcatttgta taaagactgg cgtaaattga tagataataa ggatatcgat ctcgtaatcg
    13441 taggaactcc cgatcattgg cactgtctgc aaatggtatc cgcttgccaa gccgggaagg
    13501 atgtgtattg tgagaaaccg ctgggaaata gtatcgagga atgtaacatt atggtacggg
    13561 cggcgcagaa atacaaccgg gtcgtgcagg taggccaatg gcaacgtagc gacccgcact
    13621 ggcaggacgc catgcaattc gtacatagcg gacagctggg taagatacgc accgtacgtg
    13681 tattctctta tcaaggttgg tgcccctcta tccccgtcaa gccggacgag gcagtgcccg
    13741 ctggagtgga ctatgatatg tggctagggc cggcaccacg acgcccattc aaccggaacc
    13801 gttttcattt cacattccgt tggttctggg attatgcggg aggtttgatg acagactggg
    13861 gtgttcacct gttagactac gcattatatg gcatgaacgt taccgcaccg gaatccatca
    13921 tggcttccgg aggtaaattc ggttatccgg atgatgcttg cgagaccccg gacttattgc
    13981 aaaccatcta tacattcaag gacttcaccg ttatgtggga tcatgcgatc ggtatcgacg
    14041 atggcgctta tggacgcaat cacggtttgg gatttgtagg cgagaacggt acgttggtga
    14101 tcgaccgtag cggctgggaa gtgataccgg agaaagtgaa cggacaggca cgtatggagg
    14161 cggtaccttt aaagaactca tacggcgaag ggggactgaa cttacacgta aagaatcatc
    14221 tggaatgtat caagagtcgg aatcgtaatt gcaacgcaag tgtagagatc ggggcgcata
    14281 tcgccaagtt ctcccaatta gggaatatag cctatcgcac gggtaagaaa ttatcgtggg
    14341 atggaaagag tttccatgat acggaggcgg ataaactatt gtgcaaggaa tacagggcac
    14401 cgtgggaatt accgaaaata taaggatcta gttgtagaga cggggcgtgc ctcgtctcta
    14461 caactgggta tttattgatg ttcggggcgt aacaggtcgt tcaccgtctt cacggggtta
    14521 aatgtctcga taggaacttc tacgaatacc gtgttccagt cgctcatggc accgttccac
    14581 aagcccggca attccagcgc tttcaattcg cgaccatcct tgctcttata agagatgaag
    14641 cccgtattct tatccacgta atccggcaag ttgtatttct ctcccttata attcttaacg
    14701 gcgcaaacta aatctactgg attgaagtga gtaccttgct cgaacatcgc cttcttagcc
    14761 ggatcgctca tatcgatctg ggagctttca agcacctgca aggaaaccgt accatccgga
    14821 ttctcagcca agaacggacc accacccggc tcgccaacat tcttcaccat accgcataca
    14881 cgcaacgggc gaagcagttt gctcttgata tacaggatta attcggcgtc ttccagtaat
    14941 ttcgtatccg ggttcttgat acataagtca tcctgcaaga aatggatcat ctcctctacc
    15001 tcggcatggg tatacttacc ggtctcgatc tgttccagat atctgaaggc tttctcctgc
    15061 aatgttacca agacaccggc gatcaccttc ttgtagataa ccgtagagca tttgaagcta
    15121 tccggaacca cgttatctat attcttgata aataccacgt cggcatccac gtcattcaaa
    15181 ttctcgatca aggctccatg tccacccggg cggaacaata acttatcatt cttatcgcgg
    15241 aacggcgtgt tatccatagc ggccgctacc gtatcggtac tcggtttctg gatactgaaa
    15301 gagacatcgt atttcacgga gaacttctcc tcgtactcgc cagatttatc ggcaaccaat
    15361 tgctcgaata aagcctgatg ctccggagat accgtgaaat ggatattcac ctctccggcg
    15421 ttattcttgg cgtacatggc gccttcggcc agatgttcct ccatcgccgt acgaaccgta
    15481 tcggcatatt tatggaaaag caacaagcct ttcggtagct gtccgtaatt caagcctttc
    15541 ggctccaata aattggatac cacctccttg tactcgccca aggctaccaa cgcaggaata
    15601 tctttccctg tattctccac gcacttcttg tccaaagcct tatagaaagc gaatttttcg
    15661 atctcgctaa agaatttctt ctcgaaagca ttcatcggtt ccttataatc cgcagaaagg
    15721 aactcgtaca gattcttaaa catacggcta gcggcgccgg aggcaggtac gaattttacg
    15781 attttcttgt ttttagccag ataagcgtcc caagcatcca tataagaagc ctgttcctct
    15841 ttagatatta ccataatacc tttttctacc gaagcggagg ccgctatctc aaggaaaggg
    15901 aaacctttta cgaagcaagc gagttgctct tcaatctgtt tttcgctgat tcctttggct
    15961 ttcagctgtt ctaaatcgtt tgcgtttaac atagtatagt atttaatgtg aataatctca
    16021 tcagtaacac cacaagcact tatgcgctat gtgtatcgca aatgtataaa ataaccgcaa
    16081 gatacgtgtt gaaattccat agaaaaaagt atttttacag catgttttgc ggtttgtcct
    16141 caaccgggca ataaaaatga tataactatg gatacaattg gattctttac gtctgaggaa
    16201 aagaagctgt tcttctccaa atacaggctc ctgttacgaa acctttactc tttcctcgag
    16261 agggaagata tccggaagat gaaggagctg atgaagcggg ttgtcgccct cgattgctac
    16321 ggcagggata agaatggtat caacggttta ttgcgaaata tcgacacggc cttgatcgcc
    16381 accttggaga ttggcttgaa acgtacctcg gtcatcgccc tcctattata ccgcccggta
    16441 ttgaagaagg cgatcacgat agaggaagtg gagcagaaat tcggggcaga cgtgaccttg
    16501 atcatccgtc gcctcttgaa gacctccgac ttgtatgccc ggaacaccgc cgtcaactcg
    16561 gagaatttcc atcatttgct tttctcgttt gccgaggacg tacgtgtgat cttgcttatg
    16621 atcgccgacc gcctctgcct catgcgtatg ggaaaacaga tgcaagagga tgatcgtatc
    16681 cggctggcta ccgaggcctc ttatttgtac gctcccctcg cccaccgact gggtttatat
    16741 acgatcaaga gcgagctgga agacctttcc ttgaaatata cggacaggaa acagtatgac
    16801 ttcatcaaac ggaaactgaa tgagacgaaa cgctcccgcg acgcttatat cgccgagttc
    16861 atcgccccga tcaagcggaa gctggcagcg gcaggattca agttcgatat caagggacgt
    16921 accaaatcca tacattccat taataacaag ctgaaaaagc agcaggtgga gttcgagggt
    16981 atctacgatc ttttcgctat ccggatcgta ttggatacgc cgctggagaa ggaacgctcg
    17041 gaatgctggc aagtctactc catcgtcacc gatatgtacc agcccaaccc gaagcgtatg
    17101 aaggactgga tctctatccc gaagagcaac ggttacgaga gcttgcacat cacggttatg
    17161 gggccgcaaa ataaatgggt agaggtgcag atccgtacga ggcggatgga tgagatcgcc
    17221 gagcgaggcc tagcggcgca ttggaaatac aagggcgtga aagcagagag cgggctagac
    17281 gagttcttga ataccgtacg tgccgccttg gaggccaagg agaataatcc gctcgacttg
    17341 atgcaggatt tcaagatgga tctatataag gatgagatct acgtcttcac gcctaccggc
    17401 gagcttatca agctggccaa gggagcgacg gtcctcgatt tcgcctttgc catccacacg
    17461 aagctaggaa gcaaatgcgt gtcggcgaaa gtgaacggta agaacgttcc gatcaaatac
    17521 accttgaaca acggcgatag tgtatccgtt atcacgtcgc ccgcccaaag cccgaagcgg
    17581 gattggctga acttcgtcgt cacctccaag gcccgtgtga agatcaagca ggccttgaag
    17641 gaggagacgg tgaaggccgt ggaattcgcc aaagagatgt tgcagcgccg cttcaagaac
    17701 cggaagatcg acatggacga gccaaccatg atgcgctata tcaagaagaa aggattcaag
    17761 accgtcacgg acttctacat cgagatcgcc gaggaacgcc tcgatcccaa ccaagtaatc
    17821 gacgaatatc tggaggcttt ccgcaaggag acggagacga acgagcgtac cgaggtgcgt
    17881 agcgcagagg aattcgtgac gatgactccg gtggaggaga tatcgacgaa caaggatgtc
    17941 ttggtgatcg acaagaacct gacgggtatc gaatataaac tcgccaaatg ctgcaacccg
    18001 atttatggcg acgaggtttt cggtttcgtc tccacgcagg gtatcaagat ccaccgtatg
    18061 gattgcccga acgcccaaga gatgttcagc cgcttcggtt accggatcat ccgcgcgaaa
    18121 tggagcggca agggagacaa tggctatacg gttacgttgc gggtgatcgg acgagacgat
    18181 atagcgatcg tcaccaacat cacctccgtg atcggcaagg agtcgaacgt cacgcttcgc
    18241 tcattgaata tcaactccgt ggacggatta ttccaaggga acttcaccgt attggtaaga
    18301 gatacgaccg cgttaaactt gctgacgaaa aagatcaagg cggtaaacgg cgtgaaagcg
    18361 gtagagcgat taaattctta agacagcgta ctgtgcacga agtaccgtag tactctgtac
    18421 gaagtactac agtactctct agtaagtacc gcagtacttc gtacagggga ctgggccaac
    18481 tgtaagactg tgccttgtga ctatacccgg atcacagaat cggtttcagc cccatcttct
    18541 ccgcacgttg tataaggaat tgacgggccg cctcatactc gttcgggatc acgccgtcga
    18601 ggatggcgtt cttgatcgcc tctttcagca cgccgacagg cttggaggga gccaagccaa
    18661 acgtctccat gatctcctcg ccggataccg ggggctggaa gttgcggaca cggtcttttt
    18721 cctctatatc ggccagtttc tcgcgcacct tacggaaatt gttcaagaaa cggcgaacct
    18781 tctccgggtt cttgctcgtg atatcggcct cgcacagttt catcaaatcg tcgatatcat
    18841 ctcccgcgtc aaacagcaga cggcggatcg ccgaatccgt cacctcatcg tccgacaagg
    18901 cgatcggacg catatgcagg cttaccatct tctgcacgta cttcatcttc tcgttcatcg
    18961 ggagtttcat cttcctgaaa ataccgggga tcatccgttc gccgataaaa ttatgattat
    19021 ggaacgtcca tcccaagcga gggtcgaaac gcttcgtggc aggcttggcg atatcgtgga
    19081 agagggcgct ccaacgcagc catagattat cggaagtctt gctcaaacga tccagcacca
    19141 tcaaggtatg ggcgaaatta tccttatgcc cgatcccctc cttggtctcc acgcccttca
    19201 aggcgcaaag ctcggggaaa atcaatggca ataagccgca tttatccagc aagtcgaaac
    19261 cgatagaggg ctttggcgag aggacgatct tgttcaactc atccacgata cgctccttgg
    19321 agatgatgga gatacgctcc cggttacgga tgatggcgtc gaaggtatcg ggatcgataa
    19381 agaaacctaa ttgagtggcg aaacgaaccg cacgcatcat ccggagcgga tcatcactga
    19441 aagtgatatc cgggtctaaa ggcgtacgga tcgtaagttc gtccatatcc tccaacccgc
    19501 cgaagggatc gaccaattct ccgtaacgct ccttgttcag gcaaagggcc aaggcgttga
    19561 tcgtgaaatc gcggcggttc tggtcatcct ccaaggtgcc gtcttccacg actggcttac
    19621 ggctgtcatg gctgtaggat tctttccttg cccccacgaa ttccagctcc agatcgccgg
    19681 ctttcacctg cgccgtcccg aaattcttga agacggaaag ataagcgcca cgcccgatct
    19741 tcttggccac tcgtttggcc aactcgatac cgctgccaac cgctaccacg tctatatcct
    19801 tggatgggcg gttcaagaaa atatcccgca catatccgcc tattacatat acctcaacac
    19861 ctagctcttc cgccgcctcc gatatcaaat ggaaaggctt cgcggatata tgatttacta
    19921 tctcttcctc gtttatatac atatttatgt attccaaatc caataaagag cgcaaagata
    19981 atcaaatttc atgtactttt gcggtatcaa atacattgaa cgagaaagat atgaaaaagt
    20041 tagcgatctg tataacgctc attgccgcca ttttaacggg ctgtaacgga gacgagaaag
    20101 cggctcaggc ccgtttggac aaggcccggg ccatgtacga gaataacgag tttttcgggg
    20161 cgaagaacga gatagacagt atccgggcac tctatcccaa ggaagtaaag gtactgaagc
    20221 agggattaac gcttatgcgc caagtagaag taaaggaggc ggagcgcaat atcgctttct
    20281 gcgacagctt actcccgatc aagctggacg aagtagaggg attgaagaaa ggcttcgctt
    20341 tcgagaagga ttccgtttac gaggaaatcg gcaattatat ctggaaacag cagacgatag
    20401 agcgcaacgt gcaacgttgt tacgtacgtt gcggcgtgaa cgaggagggc gagatgtatc
    20461 tggccagcgt atattacggc ggacgcccca tcgagcatac gggaatcaag ctgagcctga
    20521 aagacggcca attcgccgag accgcttcca tcccgtacga cggcggactg aattaccgct
    20581 tcaaggatat gggaagcacc acggaggtag tgacctacaa gggggagcac tgcgtcgatg
    20641 ccgtcaagtt catctacgat aacgagaaag agcggatcaa ggtggaatac acgggaggca
    20701 agccttacat tatatatatg gcggacgccg acaagaaagc gatcgtcaac accttcaacc
    20761 tcgccaccgt attaagcgat atcaagagca tgaacacctt gaaagagaaa tcagagaaga
    20821 agatcgctta tctaaagaat aaactggagg agtagaatcc ctccatacaa atggcctacc
    20881 tataaacaaa gcaccgggac ccctaccata cagtaggaat cccggcgtta gtatacagac
    20941 tgatatccac tatcagttat tcatcattta acgacgacct tctgggcggt ctcgccatca
    21001 acggaaacta ccacgatacc tttcgatgcc ggcatcacga agttatctga agaagcgata
    21061 gcggaagcgg tggtctgacc taagatgtta gacaatgtaa ccgtcttgcc tgccgcgttc
    21121 aagaccgtaa cgctagcctc gccagcgatt accgtgaagc tggcaacctc ttccaattgt
    21181 tcgttggaaa ccggagtcgg agcattctcg atcgtgaacg gaacgccaac attagacatt
    21241 accacaacat tgtttaccac acctacataa ggagtcttca actcgcccgc agccacggtg
    21301 cgattcagct ctttctggtt ctccaataag taaccaccat cctgagttgt cttgaaggcg
    21361 aacaaagcgt tgttatccaa agacggaacg atattcgctt tatcgctgaa gcctacacgg
    21421 tagtaagtag cgccattgct aacgaatgtc tcgttagaat cccgcaagga taccatatag
    21481 tagcgaggag aaacagcttt ggtagttgtc tccggcgtat agatcgatgt cgtgatgaaa
    21541 tacaacggtt taccagcgat cacggtatcg gcttcttgaa cccataaaga gaagttgtca
    21601 gtctcataag ttgacttcaa gatatcttgg ccttcgttct tcacttcggc gaagaaattc
    21661 agcggattca tcgtcaagaa cttaccattc gtaccgaaac gcttgtgaga attgtcgata
    21721 gaagcgtact ccggagcctc tacagcgaca aagtcgaagt agttaacctt atcggaaagg
    21781 atcaggttcg ccgtattcac gttcataaag acatattgag tggtcgcgcc tacccttgta
    21841 gccatctggt atttgccacc ggtcgtagcc gtattgaata cgaattccaa cggagcggta
    21901 taatcagata atttcaacgg tccgccattc tcgctggcaa ccaaatcatt actgaaacgt
    21961 tctttcaaca tataagtcgc atgatacaag gtatcaccta aagcacgggc acctaaacca
    22021 tccgttacat tctgtacgga atcttggcta accacgatac gaagagcggc tgcgttcgct
    22081 gcgtcaccgg atttaatcat caatacggaa tcagaagtaa acgcatacag atcgtctaca
    22141 cccggagtac cggagatcaa gttcaataca taaccattat cggcgagttc ctccgcagag
    22201 aagtgacgag tacccaagaa tttatccttt aaatccacat tcgcttgata ttccaccgta
    22261 atagaatcgg tgctaccccc aaatgtatag gtattggcca taccttgaac ggcgaagatc
    22321 tcctcgttag aaataatagt cgtattcgta ttacggtcta caaccgaata cattccgttg
    22381 ttttccttga tataccattg tcccttcggt tgataaatag aaggtttgaa acctgccgca
    22441 gttaccaatt tatcggaagc ggcactctta tcgtaagcga cagcgtattg tccgccctta
    22501 tcgcccttgc tcgcgctctt caagaagtat acgcctgtac ctgtagcgat cgtagaagga
    22561 gttcccttcg ttacggtaat aacaggagcg gctccttgag caggttgagt agaacccgac
    22621 tgcaagtcag atacggtcaa ggctttcgtc tcgatcacgc tggcatatac gacacgtacg
    22681 ttcggaacgg aggtcatcgg acttgcgttc acggtcggag cggcagcggc atacatagcc
    22741 aaagcgtcgt tcttcaagtt gatcgtgaaa tagaatttct ggaaatcagc gttacccagt
    22801 gtatgcaagc cactagcgtc ataggtggag tcagccgtaa acttagcccc atatacaccg
    22861 gtagcaccgg ctatcacatt cttcaatgta tcgacaccta agtattttgc tttaccatca
    22921 ctaaatactt ggtcaccttg gatctgcaag gtcacatatt tagcgttcgc aacagcgcct
    22981 gtagtgggag ccgccgtatt cttcgctatc aagttcttac cctcgaagat atttccttga
    23041 taatttcctc caaacgtcaa ttgaaagact tggaaaccat cccccagctc acttgcgctc
    23101 aaatacatag cgtcgctagg agcctctacg gtaaatttcg tagaagaggc agaagaacct
    23161 aagctcaagt ctgtcccagc tacatccaac gccaagattt gattgtttcc gtaataagcc
    23221 tgaatagcgc taccaccggc agcgtcagag aatgtccact gattcacgcc cgatgtgata
    23281 acaggctttg ccgtagatga agccgcaaac gacaaaacgg cctgtgtctt cttgttcttg
    23341 aattgataca caggaccagc aggagtcgtg cccgcattcg tgatttgcca caaggcagaa
    23401 tcaatagcgg ctttggtagc gtctgacgcc aaagttttaa caattactga gtcggctttc
    23461 tcaccactta aagacaaaac ggaagaacct gtctttaagt aataatagtt accggctttc
    23521 cactgagcct ccggaacggt cgtactcgac tgagcattag ccgagaatac gcccgcaacc
    23581 atcagggccg cagcaataag agtacatttt ttgtccataa tcaaatagat tttatttatt
    23641 aatcacagtc taaacagggg ttgtttagaa aaggttttga gggcgtatga gattaacaat
    23701 cgatttagcg tcttataaca aaaatcgtcc tattctcacg aacaggacga ctatactact
    23761 aaaaatgtaa acagtgtatt tatatagtaa tatcatgaaa ctatatattt tggagaaaaa
    23821 ccgctccacc ttcacaggca aaacggctgg aaatctaatc tactcaataa atatcttcac
    23881 aggcttactc gaaataagca tgttctttta cgacatgacc tctgtcatcg aaataaacct
    23941 tatatatctt accatttctg gaaagtaata ctaccttata cttcacaaac gtgctattgt
    24001 ttgacacctc aactgatttc accatacatc cctcatagga agtatttacc gcatcacgca
    24061 atacttgggg catatcagtt acctcgatcg gataaaattt atcctgtgcc actgtttcct
    24121 tagcgctacc gaccatcccg gcttgcgctt ctacatcagg ggcaataaat aagccacata
    24181 aagcgacaat aaccccgtaa acaatctttt tcatacctta aaaacctaaa tacctaaacc
    24241 ttttttctct tacatcataa attcgcagta tagggtgcaa tctccgtgcc aaaactcacc
    24301 ctaaaaaacg acaagagaat aataagctgc aaatccgaca attaaccaaa agcgaagaat
    24361 caatcattcg gttgccaaag tgtggaacaa accgtggaat gtggaaaatt tccccacgag
    24421 agtgtggaat ctctacacac tactataaaa aacgaggccc acccttaatc tatataagga
    24481 tgagccttaa atcattctac ttaaatataa tcaaataaaa atactaaagt aataaaataa
    24541 agttccgtaa tatcgtatac actctgtgtc taatctctaa tttgcgattc acaaagataa
    24601 atctttttgt tcaaccatct ataaaataac cgcacatcta acgaaactca aagatttttg
    24661 aacaaagaga ttccttttaa ggacaagtca tagattatca cgaacttcaa tccttcgctt
    24721 ggtgtacggt aagttgcggg aatgggaaac cgatacctac ctcattgaag gtcgcgtaga
    24781 tattcttgtt aatatcgaaa tacacgcccc aatagtcgga actgtttacc caaacacgta
    24841 ccaccacgtt tacgctgctg tccgccaagg ctgtcaaggc gataaacgga gcggccggct
    24901 cggacaagat gcgggaatcc ttcgccaata cagactctat cacttgcttt actttctcat
    24961 aatcgctgcc gtattccacg ccaaaagtcc agtctacacg gcgagtcgtc tggttactga
    25021 aattagtcac aacgccactg ctcaaagagc cgttcggtat ataaatgacc ttattatcaa
    25081 ccgtacctaa tacggtatgg aacatctgga cctctttcac ggtaccgcca acgccctgcg
    25141 cctcaatata atcacccacc ttataaggct tgaaaagaag gatgatcaat ccaccggcaa
    25201 agtttgacag gttaccgctc aatgccatac cgacagcgac accggcggaa gccaacaagg
    25261 cggcaaacga cgtagtttga acgcctaacg cccctacgac tgaaataatc aataaaatgg
    25321 ttaaactgac attcaccaaa ctgccgacaa aagtcttgac agaaggatcg atatcccgtt
    25381 tgctcaatat cttccgaacc agtttattaa gtaagtttat aaccaatcgt cccaccaaga
    25441 agacaataag ggctttaata atcgtaaaac ccaattggga gccatgctca accaaggatc
    25501 tgatagcttc ctctaattta gaactcgctt ctacagctgc taataatacc atatctcttc
    25561 tattttaatt aatctattaa ttatataaca atctgatctt ccaaaatatt atgaaatgta
    25621 gcaaaggtat aaagtttttt taatctggta aaaccatgaa ataattacgt agctttgcga
    25681 tcaatcaaat aacacgttaa attcgacagc atgaaaatcc ttgcgatact cgccgccctt
    25741 ttcctttcaa taggctatgg ccacgctcag acatacgaga agtttgtcga gaaaagtttt
    25801 gacttcttgg acaagaacga cttagtctcc gccgaagaga gcctacgagc cgccatgcgc
    25861 cttgaaccgg gcaaccccaa taactacgcc ttgctcatga atctcgggac gatacagcgt
    25921 agacaaggga aactggaaga tgcccttctc tcctataccg ccgccctaag ccgccatccg
    25981 aataatgagg ccatactgga aaatcgtgcc ggcttatata cggaaatggg tgagatcgaa
    26041 aaagcgacga acgattacaa tgccctgtta atcttgaacc cccatcatca agaggcgtta
    26101 tattgcaggg caatgcttca tttacaacat aagaactatc ttttggccga gcaggatttc
    26161 gataagatac tggaagtaaa cgagaaatcc gtgaaaggac gtctgggaca cgcgattctc
    26221 gaaaagctac gggggaatta cgatgagagc gaacgcatct ttaattactt gatcagcgag
    26281 atgccccgtg aatggatctt atacgaaggc cgtgccgatc tatacttcat gatgggcaag
    26341 aacgcccggg ctatggccga tatcaatcgt gttttcgtgg aaagtacccc gacagccgct
    26401 ttatatgtat tgcgaggcaa agtaaaactc gcccaatatg agaaggcatc ggccgcctta
    26461 gacttcaaga aagctgagga tatgggatat gataaaacga ctatcgacga gttgatgaag
    26521 atggctcgtt aaggctgttt ttatacgtat agtggcatcg gctcacgcaa gtagtggcgt
    26581 aggccaatgc cactactcgc gtgagccgat gccactatac gtgtgagcct gcgccactac
    26641 tggtgcgaaa tcggcctatt tatactactt ttccgtgata taattgacaa tccaactacc
    26701 cacttctttc gttccatatt tcgctccacc ttccacttgg atttccggcg tacggacatt
    26761 cgcatcaagg gaagcgtcta cggcctcacg gatcaaggct ccctcttctt tgaggtcgaa
    26821 atactcgaat aacatcgcta ctgaaagaat ttgcgccaag gggttcgcta tattcagccc
    26881 tttcgcctgc ggccaagagc catggatcgg ctcgaaaacc ggtgtgctct ctccggtaga
    26941 agcggaaggc agcaagccca tagagccgct gatgcaagaa ccctcgtccg tcaagatatc
    27001 accaaacgta ttctcggtta ccattacatc gaagaatttc ggctcttgga tcatacgcat
    27061 agcggcgttg tccacataca tatagtctgt cgttacttcc ggatagctag gagccatctc
    27121 ttgagcgatc tggcgccata gacgggaaga ggcaagtacg ttcgccttgt caacaaccgt
    27181 caggtgctta ttccgtttca tcgcatactc gaagcccact ttcaagatac gctcgatttc
    27241 cgggcgggta tacatattcg tatcgtatgc cttatcgtta tcttgatatt tcttaccgaa
    27301 atacatacca ccggtcaact cacggataca taagaaatcc gcgccatcca ccaattcggc
    27361 acgcaacggc gatttatgca ataagcattt gaaggtctgc accggacgga tattagcgaa
    27421 caggcccaac ttcttacgca tcgccaaaag accttgctcc gggcgtactt tcgctgtcgg
    27481 atcattatca aacttaggat cgcccacggc cgagaaaaga acagcgtcgg catccttaca
    27541 aatccgatag gtctcctccg ggaaaggatc acctacctta tcgatcgcgt cagcgccaca
    27601 aagggcatac tcatagtgaa cctcatgtcc aaatttctca caaacggcac tcattacttc
    27661 cacgccttgc acggaaatct ctggtccgat cccgtctccg ggaagtactg ctatattcag
    27721 tttcatcgta aatgtttgtt attattctct gttaaaatgt acatacttag gctccgtggg
    27781 gaaatacgtg tcatcatccc acagggtact tgtaatcatc aagtcggcgc tataacggtt
    27841 acaagcgata ggtacgttat gaacacggca ctggcgaagc aacatctgga tgtcggcctc
    27901 gtgcggttgc ggattcaagt cgtctatcaa aaagaccgcc aaatcgatct ccttacggac
    27961 aaccatagcg gcaatctcag catcgcctcc catcggaccg gaatgcatgc aagcaatatc
    28021 cgcgttcacc cctttttcct cgagagcttt acgaaccaaa tttccggtcg tacccgtaca
    28081 aacaatatgg tggtgagaca agaactcagc gttatgtacc gcccattcta ccatttccgc
    28141 cttacgattg tcgtgcgcta caagcgcgat agtcaacttt ttcataccct ttaccttttt
    28201 aattattaat cctctatctt gttcagcatc ttcaatgtcg ccttgatcgc cgcctcggtc
    28261 tgatcagcgt ccagaccacg agtcttgaaa tcgaccccgg cataattcca gctgatgacc
    28321 gtctgcacga acgcatccgt acgtcctccc ggcgggatgg ataccgaata gttcgtcaac
    28381 atcgggaacg ggcggttcaa acgggaataa atccggcgta gggcacgaac gaaagcgtcg
    28441 tattggccat caccggaagc cgattcctcg taagcctcgc cattgatctc gatcttcaag
    28501 gtagccaccg gtttcagccc ttgggccaag gataaggaat agttcaagat ccgtattttc
    28561 tgatcctcca gcgcattatc atgatgaagc acatcgctga taatataagg aagatcctcc
    28621 ggggtaacca tttctttctt atcccctaac tcaatgatcc gttccgtaac cttacgcatc
    28681 gagccctcat ccatgtcgat accgagcgct tccagattct tgcggatatt cgcttttccg
    28741 gaagtcttgc ccaaggcata ctcgcgaacc cgtccgaaac gctcaggaag caggtcgttg
    28801 caatacaggt tgttcttgct atcaccgtcc gcatggacac cggcgcattg cgtaaacaca
    28861 tgctctccga taatcggctt attgggcggg atatgcaccc cggaataggt ctcaaccaaa
    28921 cggctagcct tgtttatctt ttcctccctc aagctcgtct cctctcccaa ctggtccttg
    28981 ataacggcaa gtacgctact caaaggagcg ttacccgcac gctctcccaa accgttcacg
    29041 gtcgtatgga ttcccttgat acccgcacgg atggcggaat atacattcgc tacggcaaga
    29101 tcatagtcgt tatgcgcgtg gaagtcaaac cgtaaatcag ggtaacggtc caccatcatc
    29161 ttgcaatact cgtaggtatt tccgggattc aagactccca aggtatccgg gagcatgaaa
    29221 cggcagatcg gaagtccttt caacgcatcg attaccaaga atacgtaatc cggggaatgc
    29281 ttgataccgt tcgaccagtc ctccaaatag atattcacgt cgatcttccg tttcgccgct
    29341 tccaatacga ccgtacgaat atcgtcaacg tgttgctcgg gagtctttcg aagctgttcg
    29401 gtgacatgct tataagagcc cttgcaaagc aagttcacga cacggcaacc tgcggattca
    29461 atccagtcga gagagaccgt accatccacg aaacccaaga cctccaattt gtctaggttt
    29521 ccggaacggg cggcccaagc ggctacacgc ttcacggcct caaactctcc gtccgacaca
    29581 cgggcggagg cgatctccac ccggttcacg cctaagtcgc tcagcagcac ttgcgctatg
    29641 ctaagcttct cgtgagcggc gaaggagacg cccgaagttt gctccccatc tctgagggtt
    29701 gtatccatta tttctatcat aatcagcgtg ctgcctcgaa ggcttctatc tttgatttat
    29761 ttgccagtaa atagtcgata tcgtccaatc cgttgatcag gcaatccttt ttataggcgt
    29821 tgatctcgaa atgctcgctt ttgcccgtag ccttgttcgt gatcgtttgc tccggtagat
    29881 ttacctcgac ctcagttttc gggtccttgt aaatcgaatc gaacaattca gcgaggaact
    29941 cttcagtcac aacaaccggc agcacgaagt tgttcaactc gttgttttta tggatatcgg
    30001 cgaagaaact ggagaccacg acacggaaac cgtaatcggc gatcgcccaa gccgcatgct
    30061 cacggctgga accggaacca aagttctttc ccgctaccaa tatctttccg ctatacgtag
    30121 gatcgttcaa gacgaatgat tcgatcttat taccttcctt atcatatcgc caatcccgga
    30181 ataagttctc gccgaaccct tccttggtag tcgctttcag aaagcgggct gggataatct
    30241 ggtcggtatc cacgttctct aaaggaagag gcacgcaagt gcttgtgatt atattgaatt
    30301 ttgttttcat cttatgctac tttattagat tagtctttac atcagttctc tagggtccgt
    30361 gatcttacct gtcacagcgg cggcggcggc cacaagcggc cccgccaaga tggtgcgagc
    30421 acccggtcct tggcggccct cgaaattacg gttggaagtg gagaccgcat atttacccgc
    30481 cggaacctta tcctcattca tcgccagaca agcggaacat cccggttgac gaaggacgaa
    30541 gccggcctcg gccaaaacct tgtcgatccc ctcggcacga atctcccgtt ctacctgcca
    30601 actgccggga accagccaaa ccgttacatc atccgctttc ttctttcctt tcaccaaaga
    30661 ggcgaaagca cggaaatcct cgatacggcc attcgtacag ctacctaaaa agacataatc
    30721 cactttctta cccaacatag actcgcctgc cttgaagccc atataatcca aagacttctt
    30781 ataagagata cggcctgcct cgggcacgct ttctaaggag ggaatatctt tgctgatact
    30841 catacccatg cccgggttcg taccgtacgt aaccatcggg tcgatatcct cggcgtggaa
    30901 aacgatctcc ttatcgaact tagcgtccgg atcactatat agctgacgcc actcgctcac
    30961 cttccgctcc cattcctcgc ctcttggggc aaactcacgg tctttcaaat aatcgaaagt
    31021 aacatcatcc ggagcgatca taccgccacg ggcacccatc tcgatcgaaa ggttacagat
    31081 tgtcaaacgt tcctccatgg tcgtattacg aatcgcctcg ccagcgtact ctacgaaata
    31141 gcccgtagca ccgctggtac tcatcttact aataatgtat aaagcaaagt ccttcgccgt
    31201 aacgcccggt ttgcgtacac catcgatcgt gatacgcatc gttttcggct tacgctgcat
    31261 gatacattgg gtagccaagg tcatctccac ctcgctcgta ccgataccga aggcgatagc
    31321 gcccatggca ccgtgcgtag aagtatggga gtcgccacaa acgatcgtca tacccggctg
    31381 cgtcaagcct gtctcgggac ctaccacatg gatgatacca ttcttcggat gttgaagacc
    31441 gtaatacgtc aagccgaaat acttcgcgtt ctcttccaag gtatccactt gattcttgga
    31501 tatagggtcc tcgataggct tatcttggtt caatgtcggg atattgtggt ccggcataca
    31561 agtgatttgc gcgggacgga agggcttcaa tccacgtgca cgtaatccgg cgaaagcctg
    31621 cgggctagtc acctcatgac aatacagacg gtcgatatac aattgtatgg ttccgtcggg
    31681 caacgtgtcc accacgtgtt tgtcccagat tttctcaaat aatgtcttgc tcattgtctt
    31741 gtctattttt agtctactat aaacttattg atggcgtcca cgaaagcctc cacggaagca
    31801 gcgataatat cggtatttgc ggagaaccca taataggtag ccccgttata ctctacctgc
    31861 atatgcacct tgcccgtatc atcgctacct ttattaatgg cttggatcaa gaattcctga
    31921 atcgtcatgt cactattact aatggctttt ttcaccgcct tgatacccgc atcaaccgga
    31981 ccgttaccag ccgcggcctc gtattttctt actcccgaca aatttaaaca aatacttgcg
    32041 actgattgta ctccaacacc actagttacc tgtaaatatt ccaatttaat acggtgggtg
    32101 gccgtacgat cctttccgac caacatcaaa acatcatcat cattaatatc tttcttacga
    32161 tcggccagtt tcaagaactc atcgtacacc ttgtccaatt tctcctgctc cagatccaca
    32221 cctaaaacat gcaggcgatg cttcaacgcc gcacgaccgc tacgagcagt caatacgatc
    32281 gcattatcat caatacccac atccttcgga tcgatgatct cgtaggtttg cgcattcttc
    32341 aaaacgccat cttgatggat accggaggag tgagcgaacg cattacgtcc gacaatagcc
    32401 ttattcggtt gtaccggcat attcatcaag ctagaaacca tacggctcgt actatagatc
    32461 ttattcgtcg tgatattggt gatgatatca cgttctttat ggctcttgaa aaccatggcg
    32521 acttcttcca atgacgtgtt acccgcacgc tcaccgatac cgtttatggt tacctccacc
    32581 tgacgggctc cgttcaacac gccttgtacg gtatttgcgg tagccatgcc caagtcatta
    32641 tggcaatggg tggacaagat cgcgttatgt acgccatcca catgttccat cagatactta
    32701 atcttcgccc cgtactcatc cggcaagcaa tatcctgtcg tatccgggat attcactacg
    32761 gtagccccgg ccttgatcac ggcctccacg acacgggcta gatattcatt atccgtacgc
    32821 ccggcatcct cacaatagaa ttctacgtcc tccacgtact ttttagcgta tttcgtggcg
    32881 gcgatcgcac gctctataat ctcctctctc gtggagttaa acttgtattt gatatgagaa
    32941 tcagaagtac cgatacccgt atgaatacgt cctcgcttag cgaatttcaa cgcctcggct
    33001 gccacgtcga tatctttctc caccgcacgg gtcaaggcac agatggtcgg ccaagtcacg
    33061 gcctttgaga tctcaaccac actcttaaaa tccccgggac tggagacagg gaaaccagcc
    33121 tcgatcacat caacacctag ctgttccaac gccttagcta cttgaatctt ttccactgta
    33181 ttcaactggc atcccggaac ctgttcacca tcacgtaagg tagtgtcgaa aataaataat
    33241 ctgtctgaca taatcttata ttcttaattt actaatatcc tatactaact aaaaaagcct
    33301 ctctcacaag gaagtgagaa aggctctttc atatatcgta atgctcgcaa agcatacagt
    33361 ctcacttcct atcccgttcc cagagtagaa taatgtttag agaaataatg agactatttt
    33421 gcaagttgcg tgtcattgtt cttgtcttta ttgtttttgt ttcaacgttg caaagatacg
    33481 gccttttttg ataccaccaa atataattcg aagtttttta caggatattt cttataaaac
    33541 gtaagataaa caattacatc tgttactaaa taacactgcc catcgttggg tcgtaacgat
    33601 gggcagtata agctgcttac gttgcccatc ataaaggcct tatgatgggc agtgttatga
    33661 aatatgtgag acagctcatt ttaacgagct acgatcttct tcacgaacaa gagcagcgta
    33721 ttaccggata acatcaagga acgcaatact gttttattct taggcaaggt aagcttctct
    33781 accctattga ggagatgaga cggggcacgc cccgtctcta caactgggta atgagttaat
    33841 cttataaacc tacttttttc cttaccaaat atcttattac atggaaatta ttccatacat
    33901 ttgccactgt actaataaat aactgttacg actatgacaa aattaagcaa catccccgcc
    33961 aaggaaacta cggccaagac cgcaaagaca cgtaaggcca agaccgagcc cgcaaagccc
    34021 aagtgggatc ctaccaagcc gatgcaattc acccaagaag agatccggga acatatccat
    34081 gagattgaga agggaccgtt ctatcctatt gaagaagtac atcaaagaat aagatcatgg
    34141 atggacagct atcaaggaaa aaagtaatcg gttctcccat ttacgaggaa agccttgaga
    34201 ggactttcgt ggaaggcata gaacgattcg gtatgttcca agcccggaaa tatcttgagc
    34261 atatattgaa tacagtcgag aaactagaaa acgactatcc ttattacccc gaatgccgac
    34321 acctaaccac gaaaagccgc atgtaccgga acatcatcct agattcacac cttatcatct
    34381 accgcatcac cgaggaacgg atcgaggtgc tggacatctt ccattccgca tccagcatgc
    34441 gaaagatcaa gaaaacaaag aatatccaca tcgaataaca caaagaaagg cgagccaccc
    34501 gtaagtgacc cgcctctttt tgctgatata taaggattaa gattggatta gttgttctcc
    34561 ggacgaagct tgcgtacagt aacagctgtc tgccacatct cgctctcgcg caatgccttc
    34621 aattcagcct ccaatttctc acgataatcc ggcttagagt ttgagtcgat agagatctg
//
LOCUS       DBMDTB010000032        32642 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_530_length_32642_cov_9.996159, whole genome shotgun sequence.
ACCESSION   DBMDTB010000032 DBMDTB010000000
VERSION     DBMDTB010000032.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 32642)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 32642)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32642
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_530_length_32642_cov_9.996159"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..680)
                     /locus_tag="ACZPB4_07180"
     CDS             complement(<1..680)
                     /locus_tag="ACZPB4_07180"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 87 protein"
                     /protein_id="HIR1098038.1"
                     /translation="MRLKTLATHPVWREPRTVFGVWMLTGVIFAIVKLLIGKYNNYKI
                     FEGVYWHAIEGLTLYGDHYPEYYDSNHYGVLFSLIIAPFALLPEWLGMILWIAGNTAL
                     LFYAISRLPLSSTPKIIIYWYSYCELMTAQGVQQFNISVAAFILLSFVLILEKKDFWA
                     AGIIMLGTFIKIYPIVGLAFFFFSRQKVRLLVSCLFWGLVCFVIPVLYTPGFEYVISQ
                     YIDWFERL"
     gene            complement(822..2228)
                     /locus_tag="ACZPB4_07185"
     CDS             complement(822..2228)
                     /locus_tag="ACZPB4_07185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5723 family protein"
                     /protein_id="HIR1098039.1"
                     /translation="MNTIYNMYKRGLCALCLLTTVGMSVSAQQIRTSYFMQSSTVRTT
                     MNPAYRPERGYVSIPVLGAVGASYGTNGIAVDNFIYPKNGETVTFMDNSVNTESFLNG
                     LKDENQVNMDFGTQVLSGGWYAGKGFWTVDVSIKGLANIRAPKTLFEFMKKGNGSQST
                     YDIRNIRAYAEAYLETGVGYSRPITDKLTVGGKVKLLWGVGSMDATIDQMHAEMGETS
                     WKVTSTGTLQTNMKGLVPEMEVDEQGRDYYNSFDFDSPGLSGFGMGVDLGATYQLTEN
                     IMLSAAVLDLGFISWSKGGSTLGKLDGTFDFNGFDLAIGENNGDIPSMGDQFDAIKED
                     FENLLHFKKEGESGSTTRLRSTINIGGEYRLLENKLGIGLLSSTRLYSPKAYTELTLS
                     GNYRPVKWFEATLSYSFIHSKFKTYGIALNFSPSWINFFIGSDYMLTKVTPQCLPVSG
                     NAMNLYMGVSVPLKSFAN"
     gene            complement(2265..3323)
                     /locus_tag="ACZPB4_07190"
     CDS             complement(2265..3323)
                     /locus_tag="ACZPB4_07190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4621 domain-containing protein"
                     /protein_id="HIR1098040.1"
                     /translation="MKNKHLVMLLLSSCCLAACVDSKYDLSDVNTDDAVMGESWVAPL
                     GTGYVTSDDVVNVEKVPSIREVDGAYVMIYDGEMKIKGKSLRAASGKVEIASEDITTG
                     DIDGLFDGDFVLALTNPHITLKSNVKNASLDCSLSIEAENTSKKEATSSDFTLSTVSP
                     NIWIGPLDPKTDAFKFVKNEKLPGIVQIVPQKIHLSLSADSKQWTNAPADALSELRYA
                     VELPLTPAPEFSAVSVERIEDAFDEDFVDYIFSDGSARIYGEVTNEMPFDMSIEMVIM
                     DENNVPVDIQFPAQEVKGQSGEVIFEITKEDMPKMKDARHIDLNLHLTGRDQGEALKK
                     GQKTTFNLKLKKEGGISI"
     gene            complement(3456..4220)
                     /locus_tag="ACZPB4_07195"
     CDS             complement(3456..4220)
                     /locus_tag="ACZPB4_07195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098041.1"
                     /translation="MVKMKRLFLLCAFVSMFATCNFISAQKELGIFNSVSAGVGVGLT
                     GVDVEVATPITPYLALRGGLTFMPGFSINTDVDVDVNDPRAGVYNDTYSMDVKGSLKR
                     TSGQLLVNVYPFPHASSFFVAAGAYFGGSSLVKIEGHSDKLKDLIAQGESAGIVIGDY
                     TIPVDNNGNVSGGLKVSGFRPYLGLGFGRAVPKKRVGVMFELGVQFHGKPEVYTDSGD
                     VKDLLNEIDEDDTFTKIMDKLTVYPVMKIRICGRIF"
     gene            complement(4367..5098)
                     /locus_tag="ACZPB4_07200"
     CDS             complement(4367..5098)
                     /locus_tag="ACZPB4_07200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HIR1098042.1"
                     /translation="MGRAFEFRKARKFKRWGNMARVFTKLGKEITIAAKQGGPEPENN
                     PRLRVLMQNAKKENMPKENVERAIKRAVSKDFTDYKEMNYEGYGPFGIAIFVETATDN
                     TTRTVANVRSYFNKNGGSLGTSGSLEFLFDHKCVFHIAKKEDLSLEDLELELIDFGVD
                     EVEEDEDEVVLYGEFAQNSAIQKYLEENGFEILSSEFVRIPNDLKEVTPEQRESIEKI
                     IEKLEEDEDVQNVFHNMKEDDSEEE"
     gene            complement(5138..7600)
                     /gene="pheT"
                     /locus_tag="ACZPB4_07205"
     CDS             complement(5138..7600)
                     /gene="pheT"
                     /locus_tag="ACZPB4_07205"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005931395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HIR1098043.1"
                     /translation="MNISYNWLKEYLDFDLEPEEVAAALTSIGLETGGVEEVQTIKGG
                     LEGLVIGEVLTCEEHPNSDHLHITTVNVGGEAPLQIVCGAPNVAAGQKVVVAVNGTKL
                     YDGDECFTIKRSKIRGVESNGMICAEDEIGIGTDHNGIIVLPADAVVGTLAKDYYNVK
                     SDYVLEVDITPNRVDATSHFGVARDLAAYLKQNGKPAELRRPSVDAFKIDDETPGVEV
                     VVENTEACPRYSGVTIKGVTVKESPEWLQNRLRVIGLRPINNVVDITNFILHELGQPL
                     HSFDAGKIKGNKVIVKAAEAGTKFVTLDGVERTLTDRDLMICNVEEPMCIGGVFGGLD
                     SGVTEETTDVFLESACFHPTWIRKTARRFGLNTDASFRFERGLDPNNTMYVLKRAALL
                     IQELAGGKITGAVQDVYPTVAEPYTVEVTYEKINTLIGKDIPVETVKSILASLEMEIV
                     SETAEGLTLHVPVYRIDVQRDVDVIEDILRIYGYNNVEFSDNVKSNLSYQTPTDRSWK
                     LQNLISEQLCGCGFNEIMNNSLTRSAYYTDLSVYPEAHCVMLMNPLSADLNCMRQTLL
                     FGGLESIEHNMKRKNGNVRFYEFGNCYDYNIDNKKEDETLAQFSEDYRLGIWVAGNRV
                     ENNWAHPDEKSSVYELKAYVENILARLGVDMKRVIFGNLTNDIYSSGLSITTGSGRQL
                     GTMGIVSKKLRKMLDIDMEVYYAELSWTQLMKEIKKAKVTFSEISKFPAVKRDLALLL
                     DKSVQFSEVEKIAKDSDRKLLKEVSLFDVYEGKNLPAGKKSYAVSFFMQDESKTLNDK
                     QIDAIMKKIQTNLEQKLGAQLR"
     gene            7855..8529
                     /gene="trmD"
                     /locus_tag="ACZPB4_07210"
     CDS             7855..8529
                     /gene="trmD"
                     /locus_tag="ACZPB4_07210"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052906 - tRNA
                     (guanine(37)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HIR1098044.1"
                     /translation="MRIDILTVLPEMIEGMINCSIVKRAQDKGLAEIHLHNLRDYTTN
                     KWRRVDDYPFGGEAGMVMQIEPIDRAISALKSEREYDEVIYTSPDGETLNQPMANSMS
                     LLNNMIILCGHYKGIDYRIREHLITKEISVGDYVLTGGELAAAIITDAVVRLIPGAIG
                     DEQSALSDSFQDDLLAPPVYTRPADYKGWKVPEVLLSGHQRKIEEWRLQQAQERTARL
                     RPDLLK"
     gene            complement(8617..9570)
                     /locus_tag="ACZPB4_07215"
     CDS             complement(8617..9570)
                     /locus_tag="ACZPB4_07215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007833742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HIR1098045.1"
                     /translation="MKNVLVIGSTGQIGSELTMKLRSIYGGNIVAGYIPGAEPKGELL
                     ESGPSAIVDITNEQQIAETVSKYNIDTIYNLAALLSAVAEAKPQLAWKIGMGGLFNVL
                     EVAREMHCAVFTPSSIGVFGNNTPKDKTPQDTIRNPRTMYGVTKVSGELLSDYYNIRF
                     GVDTRSVRFPGLISYVTPPGGGTTDYAVDIYYSAAKGEKFVCPIAAGTFMDMMYMPDG
                     LRAAIEIMEADSTKFVHRNSFNIASMSFDPEIIFNNIKKYMPDFQMEYEVDPLRQAIA
                     ESWPNSLDDTCARQEWGWKPEYDLDAMTKDMLAKLKERFNK"
     gene            9750..10940
                     /gene="kbl"
                     /locus_tag="ACZPB4_07220"
     CDS             9750..10940
                     /gene="kbl"
                     /locus_tag="ACZPB4_07220"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018710485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008890 - glycine C-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006567 - L-threonine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HIR1098046.1"
                     /translation="MYGKLKEFLTNELEGIKAAGLYKNERIITTPQRADIKVNAGSDV
                     LNFCANNYLGLSDNQRLIKAAKEAMDTHGYGMSSVRFICGTQDLHKQLEAAISDYFKT
                     EDTILYAACFDANGGLFEPLFGEEDAIISDALNHASIIDGVRLCKAKRYRYANADMAD
                     LERCLQEAQAQRHRIIATDGVFSMDGNVAPMDKICELAEKYDALVMVDESHSAGVVGP
                     TGHGVAEQFDVYGRVDIFTGTLGKAFGGAMGGFTTGKKEIIDMLRQRSRPYLFSNSVA
                     PAIVGASLEMFKMLKESDALHTKLMNNVSYFRDKMLAAGFDIKPTQSAICAVMLYDAK
                     LSQDFAAKMQEEGIYVTGFYYPVVPKGQARIRVQLSAGHETEHLDKAIAAFIKVGKEL
                     GVIK"
     gene            11019..11864
                     /locus_tag="ACZPB4_07225"
     CDS             11019..11864
                     /locus_tag="ACZPB4_07225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase"
                     /protein_id="HIR1098047.1"
                     /translation="MQLSNYHSHCTFCDGRSIPEDFVRFAITHGFRAYGFSSHSPLPF
                     ETFWNMSKDDMPEYLQEINRLKQKYSDQLEIYAGLEIDYLDETYNASIPYFQELPLDY
                     RIGSIHFLPVSERLVEENMVCIDGSFREYAHSVERHFEGDVRLLVKRFFDTTMKMIEA
                     GGIDIVGHMDKIYMNGQKYEIFNFEEDWYRKPFEACLDLVQEKGLMVEVNTKNWTKKK
                     ELYPRVEYLSRMREMNIPVMVNSDCHYPDLVNDGRKEAFKLLKQAGFKSTRELVKGKW
                     QDIAL"
     gene            complement(11861..12433)
                     /locus_tag="ACZPB4_07230"
     CDS             complement(11861..12433)
                     /locus_tag="ACZPB4_07230"
                     /EC_number="2.5.1.17"
                     /inference="COORDINATES: protein motif:HMM:TIGR00636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008817 - corrinoid adenosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cob(I)yrinic acid a,c-diamide
                     adenosyltransferase"
                     /protein_id="HIR1098048.1"
                     /translation="MRIYTRGGDKGKTGIHGGERVDKDDIRIEANGTLDELNAEIGIV
                     RTLLPPDHEWQVLLGRIQREMMAVMSHVATPSAIRDKNPNPLPDDLAVFCESHIDDLS
                     AQMEDNGYFILPGGTPVSAHLQLARTITRRAERRLWTLNRKDPVPAGIMAFVNRLSDL
                     FFTMARYDMFRQGNAEERWQSFLYKRKNKS"
     gene            complement(12574..13728)
                     /gene="dnaJ"
                     /locus_tag="ACZPB4_07235"
     CDS             complement(12574..13728)
                     /gene="dnaJ"
                     /locus_tag="ACZPB4_07235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HIR1098049.1"
                     /translation="MAKRDYYEVLGVEKNASADEIKKAYRKKAIQFHPDKNPGDKQAE
                     ENFKEAAEAYDVLSDPQKRQRYDQFGHAGVGGASQGGGFGGGMSMEDIFSQFGDIFGG
                     HFGGFGGFGGFGGSRGGRRVNRGSDLRVKVKLNLKEIANGVEKKIKVKKYVPCSHCHG
                     SGAEGSEGVKTCDTCKGSGVVTRIANTILGQMQTQTTCPTCGGEGKIVVKKCTECNGE
                     GVVRDDEIITINIPAGVAEGMQLSMNGKGNAARHGGINGDLLILIEEEPHPELIRDEN
                     DLLYNLLLSVPQAALGATVEVPTIDGKAKLKIEPGTQPGKVLRLRNKGLPSINSYGTG
                     DLLVNVSVYIPETLSSTEKETLNGLENSPNFQPNKTMKEKIFSKFKHFFD"
     gene            complement(13759..14343)
                     /locus_tag="ACZPB4_07240"
     CDS             complement(13759..14343)
                     /locus_tag="ACZPB4_07240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000774 - adenyl-nucleotide exchange
                     factor activity [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_function: GO:0051087 - protein-folding chaperone
                     binding [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HIR1098050.1"
                     /translation="MSKMNPNEKKENASKNENVNNEEATNLQEEQSNAADETAGSDNV
                     SGEVEALQKKYNELNDSHLRLMAEFDNYRKRTMREKADLIKTGGEGALKNLLPIIDDF
                     ERALQNVRTAEDVEAVKEGVDLIFGKFMGYLSQQGVKPIEAIGKPFNTEEFEAIATIP
                     APEPDMKGKVLDCVQTGYTLFDKVIRHAKVVVGE"
     gene            14560..15990
                     /locus_tag="ACZPB4_07245"
     CDS             14560..15990
                     /locus_tag="ACZPB4_07245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4136 domain-containing protein"
                     /protein_id="HIR1098051.1"
                     /translation="MMRSVILSTLLLVLAVCTVSAQNRNTSICRLGFTYDISQSKNWG
                     NNKPVIKSIIPYSSAEQAGIKKYDVIEEINGVPVTEVSVDEIPQLLNPAGRNDVLLTI
                     SNLSSPSKQVLVKKDCKKSNAITEDQLASAYAMYSLETTNEQEFVCPFKTTVTSDGVD
                     FGNFKTFAFSTIDENNRKLETVINECIENELTKKGLTVDIAKPDLLIQTFYFFDKNPN
                     YLGANKVLVEKEPTYRYNFSHSKMEKFPFLNYAAAEAEAEYLLQFGIRIIDQKDIPGR
                     VLWECEANELLEDSYRLDEYARVHVPLMCMQYPYTKYGRNVPFKVSKKTYNYTGISYD
                     IDKLDQVVDVDRNSPAYAAGIRPRDIIEKIGRHKMDHSAEEFSSAYKRFITNTMQYRD
                     PKTMFTDANGFKYCMFWDVFKYPQIADASQSSDYLPAFSYLYYFAPYINPSGNNACTF
                     NIKRGKTKLEVIIRPTIRSEVTVEIK"
     gene            16006..18474
                     /locus_tag="ACZPB4_07250"
     CDS             16006..18474
                     /locus_tag="ACZPB4_07250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0045910 - negative regulation of DNA
                     recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HIR1098052.1"
                     /translation="MIYPQNFEQKTGFDKIRHLITEKCLSPLGEERVAEMGFSADFEV
                     VSKRLEQTDEFIRILHGDTEFPASYFFDVRYSLKRIRPEGTWLDERELFDLKRSLQTI
                     NDIVRFFKPMDDEEIKYPALTELAGDIFVFPQLIGKIDSILDKFGKVKDSASSTLSQI
                     RREMTITMSGISRSLQSILRAAQSDGVVDKDVTPTMRDGRLMIPVAPAFKRKIKGIVH
                     DESASGKTVFIEPEVVVEANNRIRELEGEERREIIKILTEFTNVIRPLAPDILQSYEF
                     LADIDFIRAKALFAEQVKAIKPIVEDKRQMDWVRAVHPLLFLSLQKQGKQVVPLDIEL
                     TEGKRILIISGPNAGGKSVCLKTVGLLQYMLQCGLLIPLHERSRTGIFEHIFIDIGDE
                     QSIENDLSTYSSHLTNMKYFVKNCNERTIILIDEFGSGTEPQIGGAIAEALLDRFNRN
                     HSFGVITTHYQNLKHFAEDTEGIVNGAMLYDRHLMQPLFKLSIGNPGSSFAVEIARKI
                     GLPEDVIADASANVGADYINMDKYLQDIVRDKRYWESKRQNIRQQEKKLEDVTSRYEQ
                     DLEAVNKQRKEIIREAKAEAQRILAEANAKIENTVREIKEAQAEKEQTKLARKALEEF
                     KNSVMATEEEDDKIARKMAKLKERNERKKQKQKVTAQPIFNKEVIEVGDNVRLKGQVS
                     AGTVMELQGKQAVVAFGMIKSTVKLEQLEKVSKGQIKREIQKSTFVSSQTTDNMHEKK
                     INFKQEIDVRGMRGDEALQSVTYFIDDAIQVGAGKVRILHGTGTGILRQLIRDYLRTV
                     PGVRRFQDEHVQFGGAGITVVEFD"
     gene            18490..19566
                     /gene="corA"
                     /locus_tag="ACZPB4_07255"
     CDS             18490..19566
                     /gene="corA"
                     /locus_tag="ACZPB4_07255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015087 - cobalt ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0015095 - magnesium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006824 - cobalt ion transport [Evidence
                     IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium/cobalt transporter CorA"
                     /protein_id="HIR1098053.1"
                     /translation="MRRNEYTHRRRHISNRHLSDKYYYAGEHETATGIRLTQYNEQSL
                     HTKEVRITDTSFSKLSDPDQINWFEVSGLTNADAITRIVKDFGLHNLDAKDILTPQHV
                     VKVEEYKGRMLIVLNSCYYDVNNEMRSEHISILVANNTVITFTESNNPVFEAAHKALL
                     SNMLNIRKKGSGLLLAFLLNTIIANLVESASKVEEILEDIEETLLDPKNDQGNMGSLI
                     QQHRHEYMIIRKNSLPLKDQFSKLLRTENGIITPDILPIYNDLQDQLQFVIQTTESCR
                     EITSSLVDLYISNNDLRMNAIMKRLTIVSTLFIPLTFLVGVWGMNFKIMPELDWRYGY
                     FIAWAVMIVTGVLTWLYMKRKDWY"
     gene            complement(19576..20175)
                     /locus_tag="ACZPB4_07260"
     CDS             complement(19576..20175)
                     /locus_tag="ACZPB4_07260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HIR1098054.1"
                     /translation="MTIAYLNVATDRQHLDIQREEISSFAAAKDIHVDKWVMEVSGEK
                     AKQPGPKLKLVLERLKKGDALIVSDITRLCLTLYELMGILTVCMEKDVTVYCINDRYI
                     FDDRMDRQLMINVFKQVDEIDHSLVSIRTKDALEQVKSTGKRLGRPKGSESKLFFLDA
                     HKGEIMNMLERGESVGSICEHFNVSKNTFYKYRKKFFRS"
     gene            20287..21375
                     /locus_tag="ACZPB4_07265"
     CDS             20287..21375
                     /locus_tag="ACZPB4_07265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix DNA-binding domain-containing
                     protein"
                     /protein_id="HIR1098055.1"
                     /translation="MITHIRVASQQLEQPRFESPKELVSWMGAIQAQEYEMAKWAIGI
                     RLRSSSLETVNEALYKGDILRTHVMRPTWHFVAAEDIRWMLMLSSERIKAAVMSYAKG
                     HFGKIEKTLFTRCLDQIGKILEGYKSLTKQEVTAELQKSGILPTIDHVNLFLTWGEVE
                     GIVCSGIDKGKKTTYALLDERVPPTRELCREEALARLASRYFQSHSPAQLQDFVWWSG
                     LTATECRLAINLIKTELMTETFDSREYFIHQSWKGKNESEPVLRLLPAFDEYLISYKN
                     RTDVLPLEHHPKAFNRFGTFYPVILYNGKIIGNWSRSIKKNTIQIEMDFFEKKPRIPV
                     KLIQQAEAQIDAFYRGLLYRPALQCREK"
     gene            complement(21337..21612)
                     /locus_tag="ACZPB4_07270"
     CDS             complement(21337..21612)
                     /locus_tag="ACZPB4_07270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HIR1098056.1"
                     /translation="METKFCQSCGMPLQKNEELGTNHDGSKNEEYCCYCYKDGAFTMD
                     CTMDQMIDHCVQFVDEFNKDADFHYTKEEAVANMKLFFPTLKRWAVQ"
     gene            complement(21619..22236)
                     /locus_tag="ACZPB4_07275"
     CDS             complement(21619..22236)
                     /locus_tag="ACZPB4_07275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIR1098057.1"
                     /translation="MKPDTENIYQRKINQVIDYINANLHLPLRLDIIAGQVNVSERQL
                     LRIMRGALNESLYAYVARQRVERAVLYMHTEDMSLADLASRVGYDNPQSFSKAFKKQF
                     SVSPKVYMDKLRARLREETEKWSNASVGKEIIPSGMFGTIRLQKGKYAVYTLKGSYAG
                     LQELYNAINIDFNYTKRHGMAFEEYVSYSEEDDDTQVTKIYIPIK"
     gene            22437..22955
                     /locus_tag="ACZPB4_07280"
     CDS             22437..22955
                     /locus_tag="ACZPB4_07280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HIR1098058.1"
                     /translation="MNKIKKTNMNIKKITIAMLITLISIGNINAQEMKTEIPKISEFP
                     TGNENTGFEQYFSGKSWLAPLTSNKGLNVPMFNVTFEPNCRNNWHTHTGGQILIAVGG
                     VGYYQERGKSARRLLPGDVVEIAPNIEHWHGASPDSWFSHIAVECNPQTNKNTWLEPV
                     SDEEYGKAVNDK"
     gene            complement(23157..23330)
                     /locus_tag="ACZPB4_07285"
     CDS             complement(23157..23330)
                     /locus_tag="ACZPB4_07285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098059.1"
                     /translation="MIPKVEIEAGKADLIREILGVNDLRDINLLDEYRDIFIKSQKSV
                     YENESVNDINCTD"
     gene            23546..24754
                     /locus_tag="ACZPB4_07290"
     CDS             23546..24754
                     /locus_tag="ACZPB4_07290"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016269869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004396 - hexokinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005536 - D-glucose binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0046835 - carbohydrate phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hexokinase family protein"
                     /protein_id="HIR1098060.1"
                     /translation="MEKNIFWLENDQLKEIASSFREKVEEGLKHENAEIQCIPTFISP
                     KTSDINGKALVLDLGGTNYRVATVDLGQGSPTIHPNNGWKKDMSIMKSPGYTREELFK
                     ELADMIVGIKRDEEMPIGYCFSYPAESVLSGDAKLLRWTKGVDIKEMVGQLVGKPLLD
                     YLNEHCKIKFTGIKVLNDTIASLFAGLTDNSYDAYIGLIVGTGTNMATFIPADKIKKL
                     DPSYNIQGLVPVNLESGNFHPPFLTTVDDTVDAISDSLGKQRFEKAVSGMYLGDILKA
                     AFPLDEFENKFDAQKLTAIMNYPDIHKDVYVDVAHWIYNRSAQLVAASLLGLIQLLRS
                     YNKDIQKICLVAEGSLFWSENRKDKNYNILVLEKLQELLNESALADVEIHINNMNNAN
                     LIGTGIAALS"
     gene            complement(24800..>24988)
                     /locus_tag="ACZPB4_07295"
     CDS             complement(24800..>24988)
                     /locus_tag="ACZPB4_07295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098061.1"
                     /translation="FSIDYDIQSKPLANIDMIAVIFHPLGLNPFVRCAMSELYNHFSA
                     EKVVRVSYVKNTRTFYLF"
     assembly_gap    24989..25088
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            25352..26548
                     /locus_tag="ACZPB4_07300"
     CDS             25352..26548
                     /locus_tag="ACZPB4_07300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase-like domain-containing protein"
                     /protein_id="HIR1098062.1"
                     /translation="MKLKFAKRMSYIKASEIREILKVTEREDVISFAGGLPAPELFPI
                     DEINKMNQVVLQEAGAKALQYTTTEGYYPLREWIAKRMNERLGTSFDKDNILITHGSQ
                     QGLDLSGKVFLDDGDIVLCESPTYLAAISAFKSYGSSFIEIPTDEEGMDMATLEEVLN
                     NTQNIKLIYVIPTFQNPTGKTWSLERRKKLAELSALYDIPVIEDNPYGELRFEGESLP
                     SIKSFDKVGNILCTGSFSKIFCPGFRIGWIAGDKDIIRKYVLVKQGTDLQCNTIAQMT
                     IAEYLKRYDIDEHISKIVEVYRKRRDIALECIERYFPNDIKYTHPQGGLFTWIELPEN
                     ISARDILQKCIEQKIAFVPGGSFYPVEHKENTFRINYSNMPEDRIMKGLQVIGEVLKE
                     YIHQLK"
     gene            complement(26536..27957)
                     /locus_tag="ACZPB4_07305"
     CDS             complement(26536..27957)
                     /locus_tag="ACZPB4_07305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase-like domain-containing protein"
                     /protein_id="HIR1098063.1"
                     /translation="MKKEILYQEIARTIAYQIKKGVWKAGEKLPSLRTISNENGVSLN
                     TAIQAYYELEKDGFIISRPKSGYIVNYKPIRLSVPATTQPSVKPESKEVIDLIADVYS
                     SLEIGDKSITRFSLGMPEDILLPIAKLNKELIRAMQALPGNGTRYDETQGNMRLRKSI
                     ARFTYSWKGNLTEDDIVTTAGVTNAVALALSVITKVGDTIAVESPVYFGMLQLANSMG
                     LRILELPTNPVTGIDPDALKKVLPQIKACLLISNFNNPLGSCMPDEHKRVVVDMLAGY
                     DIPLIEDDLYGDLFFGNSRPKPCKAFDKKGLVLWCGAVSKTLAPGYRVGWIAPGKFKH
                     AIIRQKNIHLISTPALNQEAVANFMENDRYENHLRKLRQELYANSIHFAHSIMDYFPE
                     NTKIVTPQGGFMLWVELDKQIDTTELYYRAMQRKISIAPGRMFTLQEQYTNCMRLSYG
                     QRWTPLLEERLKQLGDIIKNHFN"
     gene            complement(28384..28456)
                     /locus_tag="ACZPB4_07310"
     tRNA            complement(28384..28456)
                     /locus_tag="ACZPB4_07310"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(28421..28423),aa:Lys,seq:ttt)
     gene            28950..30638
                     /gene="ettA"
                     /locus_tag="ACZPB4_07315"
     CDS             28950..30638
                     /gene="ettA"
                     /locus_tag="ACZPB4_07315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0045900 - negative regulation of
                     translational elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-dependent translational throttle protein
                     EttA"
                     /protein_id="HIR1098064.1"
                     /translation="MADDKKIIFSMVGVNKIFPPQKQVLKNIYLSFFYGAKIGIIGLN
                     GSGKSTLLKIIAGIDKDYQGEVVFSPGYSVGYLEQDPKLEPGKTVKEIVQEGVQEIVD
                     TLKEYEEVNERFGDPEVLEDPDKMDALINRQAELQDKIDATDAWNLDSRLERAMDALR
                     CPPEDQVVDTLSGGERRRVALCRLLLQQPDVLLLDEPTNHLDAESIDWLEQHLQQYAG
                     TVICITHDRYFLDHVAGWILELDRGEGIPWKGNYSSWLDQKTKRMAQEEKQVSKRRKT
                     LERELEWINMAPKARHAKGKARLNSYEALLNEDQKEREAKLEIFIPNGPRLGNKVIEA
                     QHVAKAFGDKLLFDDLNFMLPPNGIVGVIGPNGAGKTTLFKMIMGMESIDKGTFEVGE
                     TVQVGYADQTHKDIDPKKTVYQVVSGGQEFIRMGGKEVNARAYLSKFNFAGADQEKLC
                     GVLSGGERNRLHLALTLKADANVLLLDEPTNDIDVNTLRALEEGLENFAGCAVVVSHD
                     RWFLDRICTHILSFEGDSNVVFYEGTYSEYEEYKRKTLGDAEPKRVRYRKLIVD"
     gene            30665..31318
                     /locus_tag="ACZPB4_07320"
     CDS             30665..31318
                     /locus_tag="ACZPB4_07320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-disaccharide hydrolase"
                     /protein_id="HIR1098065.1"
                     /translation="MKKRMLSLAVLAASLFCFSNGANAQKTEKLFNGKDLSNWNFVVD
                     KNSVPADQVYSVRDGKIFITGQPFGYMYTKEKYSDYKLHVEWRWPNGDSNANSGIFLH
                     IADLKNPFPNGIECNLQAGRAGLFVLLGGSDLVEYQQRPGEERPFFPVVKNVNPSSEK
                     PAGEWNEANIFVKDGVITVYINGVYQNTGTNKVKEGHIGLQSEGKEVEFRNVTLTKW"
     gene            31450..>32642
                     /gene="glyA"
                     /locus_tag="ACZPB4_07325"
     CDS             31450..>32642
                     /gene="glyA"
                     /locus_tag="ACZPB4_07325"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009127490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HIR1098066.1"
                     /translation="MKRDNIIFDIIEKEHQRQLKGIELIASENFVSDQVMQAMGSCLT
                     NKYAEGYPGKRYYGGCEVVDQSETIAIERLKKLFNAEWANVQPHSGAQANAAVFFAVL
                     NPGDTFLGLNLSHGGHLSHGSPVNSSGVLYHATEYNVKEDTGRVDYDQMEEVALREKP
                     KLIVGGGSAYSRDWDYKRMREIADKVGALLMIDMAHPAGLIAAGLLNNPLEYAHIVTS
                     TTHKTLRGPRGGIILLGKDFENPWGKKTPKGEIKKMSQLLDSAVFPGIQGGPLEHVIA
                     AKAVAFGEALEPEYKTYQAQVKANAAAMAKAFTDKGYKIISGGTDNHSMLIDLRTKFP
                     DLTGKVAEKALVAADITVNKNMVPFDSRSAFQTSGIRVGTPAITTRGAKEPLMGEIVE
                     LIDTV"
BASE COUNT         9362 a         7812 c         6890 g         8478 t
ORIGIN      
        1 ttcaatcgct caaaccaatc tatatactga gagatcacat actcaaaccc cggtgtataa
       61 agcaccggga tcacaaagca aaccaatccc cagaaaagac aagagactaa taatctcact
      121 ttctgccttg agaagaaaaa gaacgccaat cccacgattg gataaatctt gataaatgtt
      181 ccgagcataa taatgcctgc cgcccagaaa tcctttttct ccagtatcaa gacaaatgat
      241 aataagataa aggccgctac tgatatattg aattgctgta ctccttgagc cgtcatcaac
      301 tcacaatacg aataccaata aataatgatt ttgggggtac tcgacaatgg caatcggcta
      361 atcgcataaa ataatagggc ggtattcccc gctatccata agatcatacc cagccattcc
      421 ggtaacaggg cgaaaggagc tatgataaga ctgaataaga ctccataatg gtttgaatca
      481 taatattccg gataatgatc cccatataag gttaagcctt cgatagcatg ccagtagact
      541 ccttcaaata tcttataatt attatatttc ccgatcaaca acttgacaat agcaaaaata
      601 acacctgtta gcatccatac cccgaataca gtccggggct ctctccatac cggatgggtg
      661 gctaaagtct ttaatctcat atccaatttc ttcctttcaa tcagtccaca aagataaaaa
      721 acctaataaa acgagcctaa taaaaaagaa aagactgtct gggtatataa cccggacagc
      781 cttttccttt atgatacaga ctctattctg agtattccct attaattagc gaatgatttc
      841 aaaggaacac ttactcccat gtaaagattc atggcgttac cgctgaccgg taagcattgt
      901 ggagttacct ttgtcaacat ataatccgat ccgataaaga aattgatcca agacggtgag
      961 aaattcaagg cgataccata cgtcttgaac ttactatgga taaatgagta gctcagcgta
     1021 gcctcaaacc atttcaccgg acggtaatta ccggacaatg tcagttccgt ataggctttc
     1081 ggggaataaa gacgagtgct cgacaataaa ccgataccta acttgttttc cagtaaacgg
     1141 tactcgccac cgatattgat tgtcgaacga agacgggtag tgcttccgga ctcaccctct
     1201 ttcttgaaat gaagcaagtt ctcgaaatct tccttgatag cgtcaaactg atcgcccatg
     1261 ctcggtatat caccgttatt ctcgccaata gccagatcaa agccgttaaa gtcgaaagtt
     1321 ccatccaact tacctagcgt gctacctccc ttgctccagc tgataaaacc taaatcaagg
     1381 acagcggcgg ataacatgat attctcggtc aattggtacg tagcacccaa gtccactccc
     1441 ataccgaaac cgctaagacc cggagaatcg aaatcaaagc tattataata atcacggcct
     1501 tgctcgtcta cttccatttc cgggaccaag cctttcatat tcgtctgcaa ggtgccggta
     1561 gaggtaactt tccagctagt ctctcccatc tctgcatgca tctgatcgat cgtagcgtcc
     1621 atagaaccta cgccccataa caatttaacc ttacctccga ctgtcaactt atccgtgata
     1681 ggacgagaat atcctacacc tgtctccaaa taagcctcgg catacgccct gatattacgg
     1741 atatcatacg tgctctgaga tccattaccc tttttcatga actcgaacaa tgtcttcgga
     1801 gcacgaatat tcgccaatcc cttgatagaa acatcaaccg tccagaatcc cttgccggcg
     1861 taccagccac cggatagaac ctgcgtacca aaatccatgt ttacctgatt ctcgtccttc
     1921 aagccattca ggaaagactc ggtattcacg gagttatcca tgaacgtaac ggtctcacca
     1981 ttcttcggat aaataaaatt atccacagct attccgttcg taccatacga agcgccaacc
     2041 gcgcctaata ccggaatgga gacatagcct ctctcgggac gatacgccgg attcatcgtc
     2101 gtgcgtaccg tagaggattg catgaagtaa gaagttcgta tttgctgggc ggataccgac
     2161 attcccacag tggtcaataa acataaagca cacagacctc tcttatacat attatatata
     2221 gtattcatct ttctttttcg taatttaaat ggttagtact gggatcaaat ggagatacca
     2281 ccttctttct taagtttcaa gttgaaggtc gttttctggc ctttcttcaa agcctcgcct
     2341 tgatctctac ccgttaaatg taaatttagg tctatatgac gtgcatcctt cattttcggc
     2401 atatcctcct tcgtgatctc gaagataacc tctccagatt gtccttttac ctcttgtgcc
     2461 gggaattgga tatctaccgg tacattgttc tcatccatga tcaccatctc gatagacata
     2521 tcgaacggca tctcgttcgt aacctctcca tagatcctcg cgcttccgtc cgagaaaata
     2581 tagtctacga aatcctcatc aaaagcgtcc tcgatccgct cgacggatac ggcgctaaat
     2641 tccggtgccg gagtcaacgg aagctctacc gcataacgta actcactcaa ggcatccgca
     2701 ggagcgttcg tccattgttt gctatcagcg gacaaagaca aatgtatttt ttgaggaaca
     2761 atctgtacga ttcccggtaa cttctcgttc ttgacaaact taaaagcatc cgtcttcgga
     2821 tcaagagggc cgatccaaat attaggagac accgttgaca aggtaaaatc agaggaagta
     2881 gcctcctttt tacttgtgtt ctcagcctcg atagacaagc tacaatccaa agaggcattc
     2941 tttacattcg actttaatgt aatatgggga ttcgttaacg ccaaaacgaa atcgccatca
     3001 aacaaaccat cgatatcccc agtcgttata tcttccgagg cgatctccac tttaccagag
     3061 gcggcccgta agcttttccc cttaatcttc atctctccat catagatcat gacgtaagcc
     3121 ccgtcgactt cccgaatgga agggactttc tctacattca caacgtcatc cgacgttaca
     3181 taacccgtac cgaggggagc tacccaagac tcacccatta ccgcatcgtc cgtattgaca
     3241 tcgcttaaat catacttact atccacacat gccgctaaac agcaagatga tagcaatagc
     3301 atcaccaaat gtttgttttt catataaagt tatttttatc aaaattatga ccctaacagc
     3361 gcgcaaaaat aaacaaaata aatgaaagtt tagccataaa aaaagagtgg catcgtatta
     3421 ttaacgccac tcttagctta tactatcttt gacaatcaaa atattcttcc gcaaatacga
     3481 atcttcatga ccggataaac cgttagcttg tccatgatct tcgtaaaggt atcatcctcg
     3541 tctatctcat tcaacaagtc ctttacatcc cctgaatccg tatacacctc cggtttgcca
     3601 tggaattgca cacccagctc aaacatcacg ccaacccgtt tcttaggaac cgcacgaccg
     3661 aatccaagac ctagataagg acgaaaaccg gacactttca atccaccgga tacattaccg
     3721 ttattatcca ccggaatcgt ataatcaccg ataactatgc ccgcactttc tccttgggcg
     3781 atcaggtctt tcagcttatc actatgccct tctatcttca ccaaggaaga accaccgaaa
     3841 taggcgccgg ccgcaacgaa gaacgaagaa gcgtgaggaa acgggtaaac attcaccaac
     3901 aactgtccgg aagtacgttt caagctacct ttgacatcca tggagtatgt atcattatac
     3961 acacccgctc gcggatcgtt aacatctaca tccacgtccg tattaatgct gaaacccggc
     4021 ataaaggtaa gaccacctct caacgccaga taaggcgtaa taggagtagc gacctccaca
     4081 tctacacccg tcaaaccaac acccactcct gccgaaacag aattgaaaat ccctaactcc
     4141 ttttgagctg agataaaatt acacgtcgca aacatgctca cgaacgcaca aagaagaaat
     4201 agtcttttca ttttcaccat ataagttaaa ttgttattca ccctagactc acaaaaataa
     4261 ataaaaaaca tgaaacattc gttgtaaaaa agaaaaagcg acatcgaatt tgcctcgatg
     4321 tcgctttttt acggataaag tatactattt tacgtataag cgtacgttat tcctcctcag
     4381 aatcgtcttc cttcatatta tggaatacgt tttgaacgtc ttcgtcttcc tctaatttct
     4441 cgataatctt ctcgatagac tcacgctgtt ccggagtaac ctccttcaaa tcgttcggaa
     4501 tacgtacgaa ctcactactc aagatctcga aaccattctc ctccaaatat ttctggatcg
     4561 ccgaattctg cgcgaactca ccataaagaa caacctcgtc ctcgtcttcc tcaacctcat
     4621 ctacaccgaa gtcgatcaac tccaactcta ggtcttctaa agaaagatcc tcttttttag
     4681 cgatatggaa tacgcattta tgatcgaaca agaactccaa gctaccggat gttcccagag
     4741 aaccaccgtt cttattgaaa taactacgaa cgttggctac cgtacgagtc gtattatccg
     4801 tagcggtctc aacgaagata gcgataccga aaggaccata tccctcatag ttcatctcct
     4861 tataatccgt gaaatccttg gatacggcac gtttaatggc acgctccacg ttctccttcg
     4921 gcatattctc ctttttggcg ttctgcatca acacacgtaa acgaggatta ttctcaggct
     4981 ccggcccacc ttgttttgcc gcgatcgtga tttccttacc taacttcgtg aatacacggg
     5041 ccatattgcc ccaacgctta aactttctcg ctttacgaaa ctcaaacgct cttcccatat
     5101 gtttatcagt ttatctttat tttatgtaat taaattctta tctcaattga gcacctagct
     5161 tttgttccag attcgtctgg atcttcttca tgatagcgtc gatctgctta tcgttcaaag
     5221 tcttgctctc atcttgcatg aagaagctta cggcataaga cttcttgccc gccggaaggt
     5281 tcttgccctc gtaaacgtcg aacagagata cttccttcaa tagcttgcga tcgctatcct
     5341 tagcgatttt ctcgacctcg ctaaactgta cgctcttatc aagcaacaac gccaagtcac
     5401 gtttaacggc cgggaacttg gaaatctcgg agaaggttac tttcgccttc ttgatctcct
     5461 tcatcaattg ggtccacgac aactcagcgt aataaacctc catatcaata tccagcatct
     5521 tacgaagttt cttgcttacg atacccatcg tacccaattg acgtccggaa ccggtcgtga
     5581 tgcttaggcc cgaagaatag atatcattcg tcaagttacc gaaaataacc cgtttcatat
     5641 ccactcccaa gcgggctaag atattctcta cgtaagcctt caactcataa acggaagatt
     5701 tctcgtccgg atgcgcccag ttgttctcca cccggttgcc ggctacccag atgcctagac
     5761 ggtaatcctc gctgaactgc gccaaggtct catcttcctt cttgttatcg atattataat
     5821 catagcaatt accgaactca tagaaacgga cattgccatt cttacgcttc atgttatgct
     5881 cgatgctctc caaacctccg aacaacaagg tctgacgcat gcagttcaaa tcagcgctta
     5941 acgggttcat caacatgaca caatgcgctt ccggataaac agacagatcc gtataataag
     6001 cggagcgtgt caaggaattg ttcatgatct cgttgaaacc acaaccgcaa agttgctccg
     6061 aaatcaagtt ctgcaatttc cagctacgat ccgtaggagt ctggtaactt aaattggact
     6121 tcacgttatc gctgaactcc acgttattat atccgtagat acgaagaatg tcctcgatca
     6181 cgtctacatc acgctgcaca tcgatacgat atacgggaac atgcaaagtc aagccctcgg
     6241 cagtctcgga tacgatctcc atctcaaggc ttgccaagat acttttcacg gtttctaccg
     6301 gaatatcctt accgatcaac gtattgatct tctcgtaagt cacctcaacc gtatacggtt
     6361 ccgccacggt aggataaaca tcctgtacgg cacccgtgat cttacctccc gccaactctt
     6421 gtatcaacaa ggcggcacgt ttcaatacat acatcgtatt gttcggatcc aaaccacgct
     6481 cgaagcggaa agaagcgtcc gtattcaagc caaaacgacg agcggtcttg cgaatccacg
     6541 tcggatgaaa acaagcggat tccaagaata cgtcggtggt ctcctccgtc acgccggaat
     6601 ccaaaccgcc gaacacgcca ccgatacaca tcggttcctc gacgttacaa atcatcaagt
     6661 cacgatcggt caacgtacgc tccacgccat ccaacgtgac gaatttcgta ccagcctcgg
     6721 ccgccttgac aatcacttta tttcctttga tcttacccgc gtcaaaagag tgtaaaggct
     6781 gccctaactc atgcaggata aagttcgtta tatccactac gttattgatg ggacgaaggc
     6841 cgatcacacg caaacggttt tgtaaccact ccgggctctc cttcaccgta acgcccttga
     6901 tcgtaacacc ggaataacgg ggacaagcct ccgtattctc taccacgacc tctacgcccg
     6961 gtgtctcgtc gtcgatcttg aaagcgtcta ccgaaggacg tctcaattcg gcgggcttgc
     7021 cgttttgctt caaataagcg gccaagtcac gggcgacacc gaaatgggaa gtagcgtcta
     7081 cacggttcgg ggtgatatcc acctccagca cgtagtcgct ctttacatta taataatctt
     7141 tagctaacgt acctacaaca gcatcggcgg gaagtacgat aataccgtta tggtcggtac
     7201 cgataccgat ctcgtcctcg gcgcaaatca taccgttgga ctcaacgcca cggatcttgg
     7261 atctcttgat ggtaaagcat tcgtcaccgt cgtacagttt cgtaccgttc acggctacga
     7321 ccactttctg tccggcagcc acgttcgggg caccgcatac gatttgtaaa ggagcctcgc
     7381 cacctacatt tacggtcgta atatgtaaat ggtcagaatt cgggtgttcc tcacaagtta
     7441 acacttcacc gataaccagt ccctcaagtc cgcccttaat ggtttgaact tcctctactc
     7501 caccggtttc caaaccgata gaggtaagcg ccgcagcaac ttcttctggc tccagatcga
     7561 aatcaagata ctctttcagc caattgtaag atatattcat cgctataaaa tttattctct
     7621 aaagagacgg cctctattga tagccgccga attgacggac aaaagtacga ataataattc
     7681 aaacgataca aaaatatcct catgaacttc tacgaactct taactgcgcc aacgcatgcg
     7741 tttcattcat tcttaatttt ctatcgcgaa tcatagataa tagagactca ctttacgatg
     7801 agtcagaata aagatgtacc tttgcgggag gttttaacgt tacaactatt ttttatgcgt
     7861 atagatatac ttaccgtact tcccgagatg atcgagggga tgattaattg ctctatcgtc
     7921 aagagggcgc aagataaagg attagcggag attcatttac ataacctacg ggattacacc
     7981 actaataaat ggaggcgggt ggatgattat ccgttcggag gagaggccgg aatggtgatg
     8041 cagatcgaac cgatagaccg ggcgatctca gcgttgaaaa gcgaacggga atatgacgag
     8101 gtaatctata cctccccgga tggcgagaca ctcaaccagc ccatggccaa cagcatgtct
     8161 ttactaaata atatgattat cctctgcggg cactataaag ggatcgacta tcgtatccgt
     8221 gagcatttga taacgaaaga gatatccgta ggagactatg tccttaccgg aggagagctg
     8281 gccgccgcta tcataaccga cgccgtggta cgcttgatac cgggagcgat cggcgacgag
     8341 caaagcgccc tctccgactc cttccaagat gacttactgg ccccgcctgt ttatacacgt
     8401 cccgccgatt acaaaggttg gaaagtaccc gaggtactat tatccgggca ccagcgcaag
     8461 atcgaagaat ggcgcttgca acaagcacaa gagcgtacgg cacgcctccg gccggattta
     8521 ttgaaatagc agcgttaaaa aacaaggccg gggatcatcc ccccgatgat accccggccc
     8581 ctctatccac aaacaatcat ggctacaaca tcactcttat ttattgaaac gttctttcaa
     8641 tttagctaac atgtcttttg tcatggcatc caaatcatac tccggcttcc agccccactc
     8701 ttggcgggcg caagtgtcat ccaaggagtt cggccacgac tcggctatag cctgacgcaa
     8761 aggatctacc tcatactcca tttggaagtc cggcatatat ttcttgatat tattaaagat
     8821 gatctccgga tcgaaactca tcgacgcaat gttgaaagag ttgcgatgaa cgaacttcgt
     8881 agaatccgcc tccataatct cgatagcggc acgcaagccg tccggcatgt acatcatatc
     8941 catgaaagta ccggctgcga tcgggcaaac gaatttctcg cccttagcgg ccgaatagta
     9001 aatatcgaca gcgtaatccg tcgtaccacc acccggaggt gttacgtaag agatcaatcc
     9061 ggggaaacga accgaacgtg tgtccacgcc gaaacggata ttataataat cgcttaacaa
     9121 ctcgccggat accttcgtca cgccgtacat cgtacgagga ttacggatcg tatcttgagg
     9181 agtcttgtct ttcggggtat tgttaccgaa aacgccaata gagctcggcg taaatacggc
     9241 gcagtgcatc tcacgggcca cctcaagcac attgaacaag ccccccattc cgatcttcca
     9301 cgccaactga ggtttagcct ctgctacagc cgacaaaaga gccgccaagt tgtagatcgt
     9361 atcaatatta tattttgata ccgtctcagc gatctgctgc tcgttcgtga tatccacgat
     9421 agcggaaggt cccgattcta acaactcgcc tttaggttcc gcacccggga tataacccgc
     9481 tactatgttc ccaccgtaga tacttcttaa tttcatggtt aactctgatc cgatctgacc
     9541 ggtagaacca attactaata cattcttcat cgcgtttaat gagatttaag tttttttccg
     9601 tcggcaaagg tatagagaat aaaacagttt agacatgaat ttcttctctt ttttagtatt
     9661 aaaattcaaa aaaaaaacag acctttgtct gtcgctttga caacgaagct actactcaca
     9721 tctaaatact aataaaaaac gaagttttta tgtacggaaa acttaaagaa ttcttgacaa
     9781 atgaacttga aggcatcaaa gccgctggtt tatacaagaa cgagcgtatc attactacgc
     9841 cacagagagc cgacatcaaa gtaaatgccg gaagtgatgt tttgaacttc tgcgccaaca
     9901 actatcttgg cctgtccgat aaccaacgac tgatcaaggc cgcgaaagaa gccatggata
     9961 cacacggtta tggcatgtcg tccgttcgtt tcatctgtgg aacgcaggat ttgcacaagc
    10021 aattggaagc agccatctcc gactatttca agactgagga cacgatcctt tacgccgcat
    10081 gtttcgacgc taacggtggt ttgttcgagc cattgttcgg cgaggaagac gctatcatct
    10141 cggatgcctt gaaccacgcc tctatcatcg acggcgttcg tttatgcaag gctaaacgtt
    10201 accgctacgc taacgccgat atggcggact tggagcgttg cctacaagag gcgcaggccc
    10261 aacgtcaccg tatcatcgcc acggacggcg tgttctccat ggacggcaat gtcgctccga
    10321 tggacaagat ttgcgagctt gccgagaaat atgacgcatt ggttatggtg gacgaatctc
    10381 actctgccgg tgtcgttgga ccgacgggcc atggcgtagc cgagcagttt gatgtttacg
    10441 gacgtgtaga tatcttcacg ggtacgctgg gtaaggcgtt cggtggtgcc atgggtggct
    10501 tcacgaccgg aaagaaggag attatcgata tgttacgtca gcgttctcgc ccctacttgt
    10561 tctctaactc cgtggctccg gccatcgtag gcgcaagctt ggagatgttc aagatgttga
    10621 aggagagcga cgctttacat acgaaattaa tgaacaacgt aagttacttc cgcgacaaga
    10681 tgctggcagc cggtttcgat atcaagccga ctcaatccgc tatctgtgcc gttatgttgt
    10741 acgacgctaa gttgtctcaa gattttgccg ccaagatgca ggaagagggt atttacgtaa
    10801 ccggttttta ttacccggta gtaccgaagg gacaagctcg tatccgtgta caattgtccg
    10861 ccggccacga gactgagcat ttggacaagg ctatcgccgc gtttatcaag gtaggaaaag
    10921 agctaggcgt tatcaaataa cacctctccc attcatcata caaggccaca tccgggcaag
    10981 atgatctgga tgtggctttt taatcactaa gaacaatcat gcaactcagt aactaccata
    11041 gtcattgtac tttttgtgat ggaagaagta ttccggagga tttcgtgaga ttcgccataa
    11101 cacacgggtt ccgtgcgtac ggtttttcct cccactcgcc gcttccgttc gagaccttct
    11161 ggaatatgtc taaagacgat atgccggagt atctgcaaga gataaaccga ctgaaacaga
    11221 aatacagcga tcaactagaa atatatgccg gtctggagat tgattatctg gacgagacct
    11281 ataacgcctc gatcccctat ttccaagagt tgcctttgga ctaccggatc ggttccatcc
    11341 atttcctgcc cgtatcagag cgtctggtcg aagagaacat ggtctgtata gacggctcat
    11401 tcagggaata cgcccactcc gtggagcggc atttcgaggg agatgtccgg ttgcttgtca
    11461 agcgtttctt cgataccacg atgaaaatga tagaggccgg aggcatcgat atcgtcgggc
    11521 atatggataa gatctatatg aacggacaga agtacgagat cttcaatttt gaggaggatt
    11581 ggtatcggaa gccttttgag gcttgtctgg atctggttca ggagaaagga ttgatggtag
    11641 aggtcaacac caagaactgg accaagaaaa aagagcttta cccccgtgtg gaatacctat
    11701 cacggatgcg ggaaatgaat atccctgtca tggtgaactc cgattgccat tatccggatt
    11761 tggtgaacga cggtcgcaag gaggctttca agttgctgaa gcaagctggc ttcaagtcca
    11821 cccgtgagct cgtgaaaggc aaatggcaag atatcgccct ctaggattta tttttccgct
    11881 tatacaggaa ggattgccaa cgttcctcgg cgttcccttg acgaaacatg tcataacgtg
    11941 ccatcgtaaa gaacagatcc gataaacgat tcacgaacgc catgatcccg gcaggaaccg
    12001 ggtctttccg attcaatgtc cacaagcggc gttcggccct gcgggtgatc gtacgggcca
    12061 attggaggtg cgccgaaaca ggtgtgcctc ccggaaggat aaaatacccg ttatcctcca
    12121 tctgggcgga tagatcatcg atatgggact cacaaaagac ggccaaatca tcggggagcg
    12181 gattcggatt cttatcacgg atcgccgatg gtgtcgccac atgagacatc acggccatca
    12241 tctcacgctg tatcctaccc agcaacacct gccattcatg atcgggaggc agcaacgtac
    12301 ggacaatgcc gatctcggcg ttcaactcat ccaacgtccc attcgcctca atacggatgt
    12361 catccttatc gacacgctca ccgccatgta tgccggtttt tcctttatct cctccacggg
    12421 tatatattct cataggatac tcattttagg acttatgaaa aaagactacc gtattccggc
    12481 gataaacact atagtattca tttccaaaca ctactgtgtt tatccacgaa tactatagtg
    12541 ttctcacacg aacacaatag tctttcctat tcgttaatca aagaagtgct taaacttact
    12601 gaagattttc tctttcatcg tcttattagg ctggaagttc ggtgaattct ccaatccgtt
    12661 cagcgtctct ttctccgtag acgacaaagt ctcggggata tatacactca cgttcaccaa
    12721 caaatcgccc gtaccataac tattgatgga aggaagtcct ttattacgca aacgaagcac
    12781 cttacccggc tgtgtacccg gctcgatctt caatttcgcc tttccgtcga tggtcgggac
    12841 ctctaccgtg gctcccaagg ctgcttgcgg aacactcaat agcaggttgt ataacagatc
    12901 gttctcatca cgaatcaact ccggatgcgg ttcctcctcg ataaggatca ataagtcgcc
    12961 gttgattcca ccatgtcgtg cggcgttgcc tttaccattc atggagagct gcatgccctc
    13021 ggctacaccg gcagggatat tgatcgtgat aatctcatcg tcgcgaacga cgccctcacc
    13081 gttacactcc gtacatttct tgacaacgat cttgccctcg ccaccacaag taggacaagt
    13141 cgtctgcgtc tgcatctgcc caaggatcgt gttggcgata cgggtaacga caccgctacc
    13201 tttacacgta tcacacgtct tcacaccctc cgagccttcc gccccgctac cgtgacaatg
    13261 cgaacaaggc acatacttct tcaccttgat cttcttttcc acgccgttag cgatctcttt
    13321 caggttcagc ttcaccttca cacgcaagtc cgatccacgg ttcacacggc gtcctccacg
    13381 agaaccgccg aaaccaccga agccaccaaa accgccaaaa tgtccaccaa agatgtcgcc
    13441 gaactgggag aagatatcct ccatggacat accaccaccg aagccgccac cttgtgaagc
    13501 cccgccgaca cccgcatggc cgaattggtc ataacgctga cgcttttgcg gatcgctcaa
    13561 cacgtcgtat gcctctgccg cctccttaaa gttctcctcc gcttgcttat cgcccgggtt
    13621 cttatccggg tggaattgta tcgccttctt acggtacgct ttctttatct catccgccga
    13681 tgcattcttc tcaacgccca gcacttcata gtaatccctt ttagccatcc ttgtatttgt
    13741 tatttgccga ttttccgatt attctcccac tactacttta gcgtgacgta ttaccttgtc
    13801 aaataaggta tatccagttt gtacgcaatc caataccttg cccttcatgt ccggttccgg
    13861 agcgggaatc gtagcgatag cctcaaactc ctccgtgttg aacggcttac ctatggcctc
    13921 gatcggcttt acgccttgct gagacagata gcccatgaac ttaccgaaaa tcaagtccac
    13981 gccttcttta acggcctcta catcctcagc cgtacggacg ttctgcaaag cacgctcgaa
    14041 atcgtcgata ataggaagaa ggttctttaa cgcaccctcg ccgccagtct tgatcaaatc
    14101 agccttctca cgcatcgtac gtttacggta attgtcaaac tccgccatca agcgcagatg
    14161 ggaatcgttc aattcgttat atttcttttg caaggcttcc acctcgcccg acacattgtc
    14221 agagccggca gtttcatctg ccgcatttga ctgttcttcc tgcaaatttg tcgcttcctc
    14281 attattcacg ttttcgtttt ttgaagcgtt ttcttttttc tcgtttggat tcatcttgct
    14341 cataatctat ctgatttttt tcattactaa ctaattgtaa gcgaaatacg gtaccacata
    14401 aataccctta aaaagtatat acacagcatc catatcaagt tcatacacta ttatagcagc
    14461 aaatatattg ccaactattc caccacatca aaaatatctt tacctttgcc tatgttttaa
    14521 acgaaacagg tatttttaga gtaaataaaa ttccagaata tgatgagaag tgtgatttta
    14581 tcaacgttgc tattagtatt ggcggtctgt acggtttccg cccaaaacag gaatacatcc
    14641 atctgccgac taggcttcac atacgatatc agccagagca agaactgggg aaacaacaag
    14701 ccggtcatta aaagtatcat cccttattca tccgccgagc aagcaggtat taagaaatat
    14761 gacgtgatcg aggagatcaa cggggtaccc gtgacggagg tatctgtcga tgagatccct
    14821 caactgctga atcccgccgg aagaaacgat gtcctattga ctatcagcaa cctttcctct
    14881 ccttctaaac aagtattggt aaagaaggac tgcaagaaaa gtaacgccat cacggaagac
    14941 cagctggcgt ccgcctatgc gatgtatagc ttggagacaa ccaatgagca agaattcgta
    15001 tgcccgttca agactaccgt cacatccgac ggcgtagatt tcggtaactt caagacattc
    15061 gccttctcga ccatcgacga gaataaccgt aaactggaaa cggtcatcaa cgaatgcatc
    15121 gagaacgagt tgaccaaaaa aggacttacg gttgatatcg caaagccgga tttattgata
    15181 cagactttct atttcttcga taagaacccg aactatctgg gagcgaataa agtattggta
    15241 gaaaaagaac cgacttaccg gtacaacttc tcgcacagta agatggagaa attcccgttc
    15301 ttgaattacg ccgccgccga agcggaagcc gaatatctgt tgcaattcgg tatccgtatc
    15361 atcgatcaaa aagatatccc cggacgtgta ctctgggaat gtgaggcgaa cgagttgctg
    15421 gaagactctt atcgtttaga cgaatacgcc cgggtgcatg tcccgttgat gtgtatgcaa
    15481 tacccataca cgaaatacgg acgtaacgta ccgttcaagg tgagcaagaa gacctataat
    15541 tatacgggga tcagctacga tatcgataaa ttggatcaag tggttgacgt agatcgtaac
    15601 tctcccgctt atgcggcagg catccgtccc cgtgacatta tagaaaagat cggccgccat
    15661 aagatggatc attcggcaga ggagttctca tccgcctaca aacgctttat cacgaacacg
    15721 atgcaatatc gtgatccgaa gacgatgttt acggatgcga acggtttcaa gtattgcatg
    15781 ttctgggacg tattcaaata tccccaaata gcggatgcgt cgcaaagctc cgattacttg
    15841 ccggcgttct cttatttata ctatttcgcc ccttatatta atccgtccgg caacaacgcc
    15901 tgtacattta atataaagcg tggcaagaca aaattagaag taattatccg tcctaccatt
    15961 cgctctgaag tgacggtaga gatcaaataa agattttaca aacacgtgat atatccacaa
    16021 aattttgaac aaaagacggg ctttgataag atccgtcact taatcacaga aaaatgttta
    16081 agcccgctcg gggaagagcg ggtagcggag atgggattct ccgccgattt cgaggtcgta
    16141 tccaagcgat tggaacaaac cgatgagttt atccgtatcc tacacggaga cacggaattc
    16201 cccgccagtt atttcttcga cgtgcgctat tccttgaaac ggattcggcc ggaaggtact
    16261 tggctggatg aacgggagtt gttcgacctc aaacgttccc tgcaaacgat caatgacatc
    16321 gtacgcttct tcaagcctat ggacgatgag gaaatcaagt atccggcctt gactgaattg
    16381 gcgggagata tctttgtctt cccccaattg attggaaaga tcgatagtat cctcgataaa
    16441 ttcggcaagg tcaaggacag tgcttcctcc accctatcgc aaatccgcag ggaaatgacg
    16501 atcacgatga gcggtatttc ccgcagcctg caatccatcc tccgtgcggc acaatcggac
    16561 ggggttgtcg ataaggacgt gacaccgacc atgcgcgacg gtcgtttgat gatcccggta
    16621 gccccggcct tcaaacgaaa gataaaaggt atcgtacatg atgagtccgc cagtggcaag
    16681 acggtcttta tagagccgga ggtggtcgtg gaagcgaata accgcatccg ggaactggaa
    16741 ggggaagaac gccgggaaat cattaagata ctgacggaat tcacgaacgt gatccgtcct
    16801 ttagctccgg atatcctaca atcttacgag tttcttgccg acattgactt cattcgtgcg
    16861 aaagcgttat tcgcggagca agtcaaggcg atcaagccga tcgtggagga taagcgacaa
    16921 atggattggg tacgtgccgt gcatccgctc ttattcctgt ctttacagaa acagggcaag
    16981 caggtagttc ccctcgatat cgagctgacc gagggaaaac ggatcttgat catatccggt
    17041 ccgaacgccg gtggtaaatc cgtttgcctg aaaacggtcg gattacttca atacatgttg
    17101 caatgtggtt tattgattcc tttgcatgag cgatcaagaa ccgggatctt cgagcatata
    17161 ttcatcgata taggcgatga gcaaagcatc gagaacgatt tgagtaccta cagttcccac
    17221 cttaccaaca tgaagtattt cgtgaagaat tgtaacgagc ggaccattat cctaatcgat
    17281 gagttcggta gcggtacgga accccagatt ggcggcgcta tcgccgaggc tttattggat
    17341 cgcttcaacc ggaatcatag ctttggggta atcacgaccc actaccagaa tttgaagcat
    17401 ttcgccgagg atacggaagg tatcgtaaac ggtgccatgt tgtacgaccg ccatttgatg
    17461 cagcccttgt tcaagctttc tatcggaaat ccgggtagct cttttgccgt agagatcgca
    17521 cgcaagatcg gtctgcccga ggacgtgata gccgacgctt ccgcgaacgt cggagcggat
    17581 tatatcaata tggacaaata cctgcaagat atcgtacgcg ataaacggta ctgggaaagc
    17641 aaacggcaga atatccgtca gcaggagaaa aaactggaag atgtcacttc ccgttatgaa
    17701 caagacttgg aagccgtaaa caagcaacgg aaagagatca tccgggaggc aaaggccgag
    17761 gcccaacgta ttctagcgga ggctaacgcc aagatcgaga ataccgtccg tgagatcaag
    17821 gaggcccaag cggaaaaaga acagaccaaa ctggcccgca aagccttgga agagttcaag
    17881 aactccgtaa tggcgaccga agaagaagac gataagatcg cacgcaagat ggcgaagctc
    17941 aaggaacgga acgaacggaa gaaacagaaa caaaaagtga cggcccagcc aatatttaat
    18001 aaagaggtga tagaggtcgg tgacaatgta cgccttaaag ggcaggtttc cgccggaacc
    18061 gttatggaac tacaaggaaa gcaggccgta gtagcattcg ggatgatcaa aagcacggtt
    18121 aagctggagc agttggaaaa ggtaagcaaa ggccagatca aacgggaaat ccagaaaagc
    18181 acgttcgtca gctcccagac cactgacaat atgcatgaga agaagataaa ctttaagcaa
    18241 gaaatcgatg tgagaggaat gaggggcgat gaggcattgc aaagcgtgac ctattttatc
    18301 gacgacgcca ttcaagtcgg ggcaggcaag gttcgtatct tgcatggaac cggtacgggt
    18361 atcttacgtc agctaatccg ggattatctg cgcacggttc ccggtgtccg tcgttttcaa
    18421 gacgagcatg tgcagttcgg aggcgccggc atcaccgttg ttgaattcga ttaaaaagag
    18481 atccttatta tgagacggaa tgaatataca cacaggagaa gacatatatc caaccggcat
    18541 ttatcggata agtattatta cgccggcgaa catgagacag caaccggcat ccgtctcacg
    18601 caatacaacg aacaatcttt gcatacgaaa gaggtgcgga taaccgacac ctctttcagc
    18661 aaactatccg acccggatca gatcaattgg ttcgaggtta gcggattgac caacgcggat
    18721 gccattaccc gtatcgtaaa agatttcgga ctgcataatc tggacgctaa ggatatcttg
    18781 actccccaac acgtggtcaa ggtagaggaa tacaaaggac gaatgcttat cgtattaaac
    18841 tcctgctatt acgatgtcaa taacgagatg cggtctgagc acatcagtat actggtagcg
    18901 aacaatacgg ttatcacttt tacggaaagc aacaaccccg tattcgaggc cgctcataaa
    18961 gcgctactat ccaacatgct gaacatccgg aaaaaaggca gtggattgct gctcgctttc
    19021 cttctaaaca ccatcatagc gaatctagta gaatccgcct caaaggtaga agagatacta
    19081 gaggatatag aagagacttt gctcgatcct aagaacgatc agggtaatat gggttcccta
    19141 atccaacaac accgccatga gtacatgatt atccgtaaga atagcctacc gctgaaagat
    19201 caattctcaa aactattacg aacagagaac gggattatca ccccggatat cctgccgatc
    19261 tataatgacc tgcaagacca actccaattc gttatccaaa caacggaaag ctgccgggaa
    19321 atcacctctt cccttgtcga tctttatata tccaataacg atcttaggat gaacgccatc
    19381 atgaaacggc tgacgattgt ctccaccctt ttcatccctt tgacattctt ggtgggcgta
    19441 tggggtatga acttcaagat aatgccggaa ttggattggc gttacggtta tttcatagct
    19501 tgggccgtca tgatagttac cggagtattg acttggctat atatgaaacg aaaggattgg
    19561 tattaaaacc aatccttacg atctgaagaa tttcttccta tacttataaa aagtattctt
    19621 agagacgttg aaatgctcgc aaatcgatcc taccgattct ccccgctcca acatgttcat
    19681 gatctccccc ttatgggcgt ctaagaagaa caacttggat tccgagcctt taggacgtcc
    19741 caaccgcttt cccgtacttt tcacctgttc caaggcgtct tttgtacgta tggaaaccag
    19801 actgtgatca atctcgtcta cttgcttgaa gacattaatc atcaattggc gatccatccg
    19861 gtcatcgaat atataacggt cgtttataca atagaccgtc acgtccttct ccatgcaaac
    19921 ggtaagtatc cccatcaact catataaggt aagacacaaa cgggtaatat ccgatacgat
    19981 caaggcatcc cctttcttca agcgttcgag aacaagtttt aactttggtc ccggctgttt
    20041 cgctttctct ccggatactt ccatgaccca tttatccaca tggatatctt tggccgcggc
    20101 aaaagaagag atctcttccc tttgaatatc caagtgttgc cggtctgtag ccacatttaa
    20161 atacgctatc gtcataaatt tcactaattg tttctagcgt gaaggtacaa aaagaatgag
    20221 tatatcttca agattatggg atgtttaacg ctttatttcg tacatttgcg tttatattca
    20281 tatattatga taacacatat acgagtagct agccaacaat tggaacaacc ccgattcgag
    20341 tccccgaaag agttggtctc ttggatgggc gctatccagg cacaggagta tgagatggcc
    20401 aaatgggcga tcggtattcg cttgagatcc tcttcccttg aaacggtaaa tgaggctttg
    20461 tacaaaggtg atattctacg tacccatgtg atgcgtccta cttggcattt cgtggccgcc
    20521 gaggatatcc gttggatgct tatgctatct tccgagcgta tcaaggctgc cgttatgtcg
    20581 tacgccaagg gacatttcgg gaagatagaa aaaacgctgt tcacaagatg cctagatcag
    20641 atcggaaaga tactggaagg atacaaaagc ctgaccaaac aagaagtaac ggcggaattg
    20701 caaaaatccg ggattttgcc caccatagat cacgtaaacc ttttccttac atggggtgag
    20761 gtggaaggca tcgtctgtag cgggatcgat aaaggaaaga aaacgactta cgccttattg
    20821 gacgaacgtg tccctcctac tcgtgaactt tgcagggaag aggctctggc gagattggca
    20881 tccagatatt ttcaaagcca ctcccctgcc cagttacagg attttgtttg gtggtccggg
    20941 ctaaccgcta ccgagtgtag gctcgctatc aatctgatca aaacggagtt aatgaccgag
    21001 acgttcgatt cccgtgaata tttcatccac caatcatgga aaggaaaaaa tgagagcgaa
    21061 cctgtactgc gtctcctccc cgccttcgat gaatacttga tcagttacaa aaaccgcacg
    21121 gacgtattgc cgctagaaca tcatccaaaa gcgttcaacc gattcggcac cttctacccg
    21181 gttatcttat ataacggaaa gataataggt aattggagcc gctccattaa gaaaaacacc
    21241 attcaaatag aaatggactt tttcgagaag aagccccgca ttccagtgaa attaatccag
    21301 caggccgaag cgcaaataga cgctttttat agaggcttat tgtaccgccc agcgcttcaa
    21361 tgtagggaaa aataatttca tattcgctac ggcctcctct ttcgtataat gaaagtccgc
    21421 atctttattg aactcatcga caaactggac acaatgatcg atcatctgat ccatcgtaca
    21481 gtccatcgtg aaggccccgt ccttataaca atagcaacaa tattcctcat tcttgcttcc
    21541 gtcatggttc gttcctaact cctcattctt ttgcagcggc ataccgcagc tttggcaaaa
    21601 ttttgtttcc atactaattt attttattgg tatataaatc tttgtcactt gcgtatcgtc
    21661 atcctcttcc gaataactca catattcctc aaacgccatt ccatgccgtt tggtataatt
    21721 gaaatctata tttatagcat tatatagttc ttgtaatccc gcataactac cttttaaggt
    21781 ataaaccgca tattttcctt tctgcaaacg aatcgtaccg aacatccccg atggaataat
    21841 ctccttcccg accgaagcat tactccactt ctcggtctct tctctcagac gtgctcgcaa
    21901 cttatccata taaactttcg gagatacgct gaattgtttc ttgaacgctt tcgagaaaga
    21961 ttggggatta tcatagccta cccgactcgc tagatctgcc agactcatat cttccgtatg
    22021 catatataga accgctcgct ctacacgttg cctcgccaca taagcatata atgactcatt
    22081 caaggctcct ctcataatac gtagtagctg ccgctcggac acgtttactt gcccggctat
    22141 tatatccagt cgtaaaggga gatgcaaatt cgcattgata taatcaatta cttgattaat
    22201 tttccgttga tatatgtttt ccgtatcagg cttcatccta tagattctta tgatgacaaa
    22261 aatacataat cccaacagac tgacaattgt ccaatctcgc caatttgaga tttcccctat
    22321 atttttttaa aagccatcaa cttcaagatt ctatagattg taaaatcagt aattttgtta
    22381 cacttatcag taattggtat acaaaagcaa tggaatatct taaataattt tgtaatatga
    22441 ataaaatcaa gaaaacaaat atgaatataa agaaaataac cattgccatg ttgatcacat
    22501 taatctccat tggcaatata aacgcacaag aaatgaaaac tgaaattcca aaaattagtg
    22561 aattccctac aggaaatgaa aacaccgggt ttgaacaata tttctcgggg aagtcttggc
    22621 tggcgccatt aacaagcaac aagggtttaa acgtaccaat gtttaacgta acgtttgaac
    22681 ctaactgccg aaacaactgg cacacgcata caggaggaca aatactcatc gccgtaggtg
    22741 gtgtgggtta ttatcaagaa cgaggtaaaa gcgcccgtcg tttactaccc ggggatgttg
    22801 tcgaaatcgc accaaacata gagcattggc acggcgcctc accggacagt tggttttcgc
    22861 atatcgccgt agaatgtaat ccccaaacca ataaaaacac ttggcttgag ccggtaagtg
    22921 atgaggaata tgggaaggcc gtaaatgata agtagtagat tttccttatc gtttacacaa
    22981 accgagccta aaagacactc cggtttcccc tagaagaaac tgcagtatct attctagcgg
    23041 gaaactgtag tttcctaaga aagaaatata aaaaactgta atatacaagt aaacagaata
    23101 ttgaataata tattctcatc ctatgccctg tatataagac attcttctcg caaaattcaa
    23161 tccgtgcaat taatatcatt aacagattca ttctcataca cagacttttg tgattttata
    23221 aatatatcac ggtactcatc aagcaagtta atgtcccgca aatcattaac gcctaaaatc
    23281 tcacggatta aatccgcctt gcctgcttct atctccactt tcggtatcat atatcttaat
    23341 ttagattaat aaataaaatc atctgtttgg tgttttaaac agacatcgtc acccttttgt
    23401 ttatacaaaa tttaaattta acacaacaaa ttttacagta tccgaaattt atccccttaa
    23461 cttaatcaac caataaggat agtcaaatcc ctttctaaat tgttattcac taacaaggat
    23521 atttcaaaat caaaaaatca atcttatgga gaaaaatatt ttctggttag aaaatgacca
    23581 actcaaagag atagccagtt catttcggga aaaggttgaa gagggattaa aacatgaaaa
    23641 tgcggagata caatgcatac cgacttttat ctctcccaaa acctctgata ttaatggaaa
    23701 agcattggtt ctcgatttag gaggaaccaa ctatagagta gcgaccgtcg atcttggaca
    23761 aggatcacca accatccatc ccaacaatgg gtggaaaaaa gacatgtcga tcatgaaatc
    23821 accgggatat actcgtgagg agctatttaa agaattagcc gatatgattg tcgggataaa
    23881 acgggatgag gaaatgccaa tcggctattg tttttcttat ccagcagaat ccgtactcag
    23941 tggagacgcc aaattgttac gttggacaaa aggagtcgac attaaagaaa tggtagggca
    24001 attagttggc aaaccacttc tcgactacct aaacgaacat tgtaaaatca aatttacagg
    24061 tattaaagta ttaaacgata ctatcgccag cttgtttgcc ggcctaaccg acaatagcta
    24121 tgacgcctat atcggtctga tcgtaggaac aggcaccaac atggccactt tcattccggc
    24181 agataaaata aagaaattag atccgagcta taatatacaa ggcttagtcc ctgtcaacct
    24241 agagtcgggc aacttccatc ctccattcct cacgacagtc gatgatacgg ttgacgccat
    24301 ttcagacagc cttggaaaac agcggtttga gaaagcggtt tcgggtatgt atctaggcga
    24361 tatattgaaa gcggctttcc ctttggatga gtttgagaat aaattcgatg cccaaaaatt
    24421 gaccgctatc atgaactatc cggatattca caaggacgta tatgtagatg tagctcattg
    24481 gatctacaac agatcagcac aattagtcgc cgcatcgcta ctgggcctta ttcagttact
    24541 gagatcatat aataaagata tacaaaaaat ctgtctagta gccgaaggca gtctattttg
    24601 gagcgagaat agaaaagata aaaactataa cattcttgtt ctggagaaat tacaagaact
    24661 ccttaatgaa tccgcattag cggatgtcga aatccatatc aacaatatga ataacgcaaa
    24721 cttgatagga acaggtatag cggcgctctc ttgaaatcaa tatgaatgaa gtgaatcttg
    24781 aactataaaa ttacgttttt caaaataaat agaaagtgcg ggtattcttt acatacgata
    24841 cccgcactac tttttccgca gaaaaatgat tgtataattc actcatagcg catcgcacaa
    24901 atggattcag ccccagagga tgaaatataa ccgcaatcat atcaatatta gctagtggtt
    24961 tggattggat atcgtaatca atagagaann nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    25021 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    25081 nnnnnnnnag aaaaccttgc cgaattaata ttagtatttc tttctcacgc ttggttaatt
    25141 gaggttcggc tagaataact gtcgacgcaa gtatcagtcc tgtctttcta ttgataactg
    25201 tccgtttaat tctttcggta ggcgatacaa tcgggataat acttggttcc gaaaatctgt
    25261 acccgctgat attgtgcaaa ttgtatctgt tctcatttat ctattatgct ttactttgca
    25321 ttattttagt tttcaaatat atttaatgat tatgaagttg aaatttgcca agagaatgtc
    25381 ttatataaag gcttcggaaa taagagaaat actcaaagtt acagaacggg aagatgttat
    25441 ttcatttgct ggtggactac ctgcccctga gctattcccc atagatgaaa ttaacaaaat
    25501 gaatcaggtc gttttgcaag aagcaggagc aaaagctctt caatatacga ctactgaagg
    25561 gtattatcct ttacgtgaat ggattgccaa acgaatgaat gaacgcttag ggacatcgtt
    25621 tgataaggat aatattctta taactcacgg ttcgcaacaa ggattagatt tatccggaaa
    25681 agtatttctg gacgatggtg atatcgtatt gtgtgaaagc cccacctatt tagcagcaat
    25741 tagcgcattc aaatcatatg ggagtagctt cattgaaatt ccaacagatg aagaaggcat
    25801 ggatatggct actttggaag aggtactgaa taatactcaa aatataaaac taatatatgt
    25861 aataccaacc tttcaaaatc ccactggaaa aacatggagt ttggaaagac gaaaaaaact
    25921 ggctgaacta tctgctttat atgatattcc tgttattgaa gataaccctt atggagaatt
    25981 aaggtttgaa ggagagtctt taccctctat aaagtctttt gataaggtag gtaatatctt
    26041 atgtactggt agtttttcta aaatcttttg tccgggcttt cggattgggt ggattgcagg
    26101 tgataaagat attatccgca agtatgtgtt agttaagcag ggcactgatt tgcagtgtaa
    26161 cacaatagct caaatgacta ttgccgaata tctaaaacga tatgatattg atgagcatat
    26221 tagcaaaata gtagaagtct acagaaaacg cagagatata gcattagaat gtattgaacg
    26281 ctattttcct aatgacataa aatatactca tcctcaaggc gggttattta cttggattga
    26341 attacccgaa aatatttcag cgcgtgacat cctgcaaaaa tgcattgaac agaaaatagc
    26401 ctttgtaccc ggcggttcat tttatcctgt tgagcacaaa gaaaatacat ttagaataaa
    26461 ttactctaat atgccagaag atagaatcat gaaaggactt caagtaatag gggaagtact
    26521 aaaggaatac atacatcagt taaagtgatt tttaattata tcccccaatt gttttaaacg
    26581 ttcttcaaga agtggagtcc atcgttgtcc atagcttaaa cgcatacaat tggtatattg
    26641 ctcttgtaat gtaaacatac gtccgggggc tatgcttatt tttcgctgca tagcccgata
    26701 ataaagttct gttgtatcaa tctgtttgtc taattccacc caaagcataa atcctccttg
    26761 tggagtaaca atttttgtat tctcggggaa gtaatccatg atggaatggg caaaatgaat
    26821 actgtttgcg tataattctt gtcgcagttt acgtaaatgg ttttcgtatc tgtcattctc
    26881 catgaaattg gcaaccgctt cttgattaag cgcaggcgta gaaataaggt gaatattctt
    26941 ttggcgaata atagcatgtt taaatttgcc gggagcaatc catcctaccc gataccccgg
    27001 cgctaatgtt ttagataccg caccacacca taaaacaagc cccttcttgt caaaagcctt
    27061 gcagggctta ggacgtgaat taccaaaaaa taaatcacca tataaatcat cctcgatcaa
    27121 aggtatatca tatccggcca gcatatcaac aactaccctt ttatgttcat caggcataca
    27181 acttcccaat gggttattaa agttgcttat aagcaggcaa gctttaattt gtggtaaaac
    27241 ttttttcagc gcatctggat caatccctgt tactggattg gtaggtaatt ccaatatacg
    27301 caaccccata ctattggcta attgtaacat tccaaaatag accggacttt caaccgcaat
    27361 agtatctcct accttagtaa ttacagataa agctaaagca accgcattag taactccagc
    27421 agttgtcact atatcatctt ctgtcaagtt tcccttccaa ctatacgtaa aacgagctat
    27481 agatttacgt aatcgcatgt ttccctgtgt ttcatcatac cgggttccat tacccggaag
    27541 tgcctgcata gctcttataa gttctttatt aagttttgca attggtaata aaatatcttc
    27601 gggcattcct aatgaaaatc gagtgatcga tttatctcct atttctaacg agctgtatac
    27661 gtcagcaatc aaatctatca cctctttgct ctcaggcttt acagacggtt gtgttgtcgc
    27721 tggaacagat aggcgtatgg gtttgtaatt gacaatatac cctgattttg ggcgtgatat
    27781 tataaatccg tctttttcca attcataata tgcctgaatt gcagtattaa gacttacacc
    27841 attttcattg ctaatagtgc gtaaagaagg tagtttctca ccagctttcc acacgccttt
    27901 cttaatttga taggcaatag ttctcgctat ttcttgatat aggatttctt ttttcatact
    27961 tgtcaggtgt tatctgtatc ctgcaaatat acaaaaatcg tgtctgtatc tgttttggac
    28021 tttgaattac ttttacagaa tgacttttgt attgctttgc tattcttaaa tgaaagaaag
    28081 gtattcgagt aaacaactga atttaaacac cattaataaa aaaatcacag taaaacaggt
    28141 ttcagatgat aatatctaaa atcaatacag agattgaaac cttctgcctg gatagtgatt
    28201 tccgacaatc gtacccccta atcgtttttt ggggaagggg gtacgatttg gatactcaac
    28261 cgtgtctttt cgtgcccctt ttttgtcttt caggcaagac tgaaacaata aaaaaagtcc
    28321 tacaatacgt tgatattgta ggacttgtct cttttttgtc gccgtttggc tttgttctta
    28381 atgtgatccg cctggggctc gaacccagga ccccaacatt aaaagtgttg tgctctacca
    28441 gctgagctag cgaatcatcc tgtgcgttac ttttgtaatg cgagtgcaaa gatagggggt
    28501 tttattttat tatacaaatt tcaagaggga taaattttag ttttttcatg gggagcaaac
    28561 gcaagaaaca agatataagc actttacatc acgtattaca tcatgcataa accggttaca
    28621 tatcttcacg agacgaagac gaaccacaat cctaaatcgt taggatcaca caacctaaag
    28681 ccacatgatc gcacagtcct aaccacaacg ccgcacaacc tctcctaccc tcatttatga
    28741 taacgctaaa gctcaacttc cgaggaatag catatctacc ggcttcttgc acaagagaat
    28801 tgaaccgagt aatctccaca cgccaaactt ggcaatcggt agatatctga tacctatgat
    28861 ctttgttaat ttgtaaaata aaagatattt acgtagattt gtacaccatt attttaagtt
    28921 aaggaaccaa ttaacacaca aaaaattata tggcagacga taagaagatt attttctcga
    28981 tggtaggcgt gaacaagatc tttccgcctc aaaaacaggt tttaaagaat atatatctgt
    29041 cctttttcta tggggcgaag atcggaatca tcggattgaa tggttccggt aaatctacgt
    29101 tgctgaagat tatcgccggt atcgataagg attatcaggg agaggtggtc ttctcccccg
    29161 ggtattccgt agggtatctg gagcaggacc ctaagttgga gccgggcaag accgtgaagg
    29221 agatcgtgca ggaaggcgtg caggagatcg tggacacctt gaaagaatat gaggaggtga
    29281 acgagcgatt cggcgatccg gaggtgctgg aagatccgga taagatggat gccttgatca
    29341 accgtcaggc ggagttgcag gacaagatcg acgctacgga cgcatggaac ctcgacagcc
    29401 gtctggaacg tgccatggac gctttgcgtt gtccgccaga ggatcaggtg gtggatacgt
    29461 tgtccggagg cgagcgtcgc cgggtggccc tttgccgatt gctgctccag cagccggacg
    29521 tattgctgtt ggatgagccg accaaccact tggacgccga gtcgatcgac tggctggagc
    29581 aacatctgca acaatatgcc ggtaccgtta tctgcatcac gcacgaccgt tacttcctag
    29641 accacgtggc cggatggatc cttgagctgg atcgtggcga gggtatccct tggaagggta
    29701 attactcctc ttggctagac cagaagacga agcgtatggc tcaagaagag aagcaagtca
    29761 gcaagcgtcg taagaccttg gagcgtgagc tggaatggat caatatggcg ccgaaggccc
    29821 gtcacgccaa gggtaaggca cgtctgaact cgtacgaggc cctcttgaac gaggaccaga
    29881 aggagcgtga ggctaagctg gagatcttca tcccgaacgg ccctcgcttg ggcaataagg
    29941 tgatcgaggc acagcatgtg gcgaaggcgt tcggcgataa gctgctgttc gatgatttga
    30001 acttcatgct tcccccgaac ggtatcgtgg gagtcatcgg gccaaacggt gccggtaaga
    30061 ctaccttatt taagatgatc atgggcatgg aaagcatcga caaggggacc ttcgaggtgg
    30121 gcgagaccgt acaagtaggt tacgccgacc agacccataa ggatatagac ccgaaaaaga
    30181 ccgtttacca agtcgtatcc ggcggacaag aattcatccg tatgggcggc aaggaggtga
    30241 acgcacgcgc ttacctgtct aaattcaatt tcgcgggagc ggatcaagag aagctatgcg
    30301 gcgtactctc cggaggagag cgtaaccgcc tgcatctggc gctgacgctg aaagcggacg
    30361 caaacgtatt gctgctcgac gagccgacca acgatatcga cgtgaacacg ctacgtgcct
    30421 tggaggaggg gctggagaac ttcgccggtt gcgccgtcgt cgtctctcac gaccgttggt
    30481 tcttggaccg tatctgtacc catatcctgt cgttcgaggg tgattccaac gtggtcttct
    30541 acgaagggac ctattccgag tacgaggaat acaaacgtaa gaccttgggc gacgccgagc
    30601 cgaaacgggt acgctatcgc aaactaatcg ttgattaatc atactataaa tagagtttaa
    30661 tgccatgaaa aaaagaatgc tatctttggc tgtattagcc gcctcgctct tctgtttctc
    30721 caatggggcg aacgcacaga agaccgagaa actgttcaac gggaaagacc tgtctaactg
    30781 gaatttcgta gtcgacaaaa actccgtccc cgccgatcag gtctattccg tacgcgacgg
    30841 taagatcttc atcaccggcc agcctttcgg ctatatgtac accaaggaga aatacagcga
    30901 ctataaattg cacgtggaat ggcgttggcc gaatggggat tccaacgcga acagcggcat
    30961 cttcctgcat atcgcagacc taaagaaccc cttcccgaac gggatcgagt gtaatctgca
    31021 agccgggagg gccggattgt tcgtactgct gggaggctcc gaccttgtcg agtaccagca
    31081 acgcccggga gaggaacgtc ccttcttccc tgtcgtaaag aacgtgaacc cgtccagcga
    31141 gaagcccgcc ggagagtgga acgaggcgaa catcttcgtg aaagacggcg tcatcaccgt
    31201 ttacatcaac ggcgtatacc agaacaccgg aaccaacaag gtgaaggaag gccatatcgg
    31261 gctacagagc gagggtaagg aggttgagtt cagaaacgta accctcacca agtggtaagc
    31321 ggagccgttt ccggcgcatc tgtaataatt aaacggaatc ttttaaatag tattaaaata
    31381 atatagtaca ttcgcgagga ttccttttca atgaggaaca tatcattgca ataaccaatt
    31441 taagaggtaa tgaaaagaga caacatcatt tttgacatta tcgagaagga gcaccaacgc
    31501 caattgaaag gcattgagtt gatcgcttcc gagaactttg tcagcgacca ggtcatgcag
    31561 gccatgggaa gctgtctgac caacaaatac gccgagggat atcccggcaa gcgttattat
    31621 gggggttgcg aggtagtaga ccaaagtgag acgatcgcta tcgaacggtt gaaaaagcta
    31681 ttcaacgccg aatgggccaa cgtgcagcct cactccgggg cgcaggccaa cgcagccgta
    31741 ttcttcgccg tattgaatcc gggcgacacg ttcctcgggt tgaacctgtc gcatggcgga
    31801 cacctgtccc acggttcacc agtaaatagc tccggcgttc tctatcacgc taccgaatat
    31861 aatgtaaagg aagataccgg acgggtggac tacgaccaga tggaggaagt agcccttcgt
    31921 gagaaaccga aattgatcgt tggcggtggt tccgcttatt cccgtgactg ggattacaaa
    31981 cgtatgcgtg agatagccga caaggtaggc gccttattga tgatcgatat ggctcacccg
    32041 gcaggcctga tcgccgccgg tttgctgaac aacccgctgg agtacgctca catcgtaacg
    32101 tctacgacgc ataagaccct gcggggtcct cgtggcggta tcatcctgct gggtaaggat
    32161 ttcgagaatc cttggggcaa gaagacaccg aaaggcgaga tcaagaagat gtctcagttg
    32221 ttggactccg ccgtattccc gggtatccag ggcggtccgc tggagcatgt gatcgcggcc
    32281 aaggccgtag ccttcggaga ggctttggag ccggaataca agacgtacca agcacaggtg
    32341 aaagcgaacg ccgccgctat ggccaaggcc ttcacggaca aagggtacaa gatcatctcc
    32401 ggcggtacgg acaaccacag catgctgatt gacctgcgca cgaagttccc cgacctgacc
    32461 ggtaaggtgg ccgagaaagc cttggtagcc gccgacatca cggtgaacaa gaacatggtt
    32521 ccgttcgaca gccgctcggc cttccagacc tccggtatcc gtgtgggtac gcccgctatc
    32581 acgacccgtg gcgctaaaga gccgcttatg ggcgagatcg tggaactgat cgacaccgta
    32641 tt
//
LOCUS       DBMDTB010000033        32476 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_534_length_32476_cov_10.905884, whole genome shotgun sequence.
ACCESSION   DBMDTB010000033 DBMDTB010000000
VERSION     DBMDTB010000033.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 32476)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 32476)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32476
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_534_length_32476_cov_10.905884"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            408..1502
                     /locus_tag="ACZPB4_07330"
     CDS             408..1502
                     /locus_tag="ACZPB4_07330"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1098067.1"
                     /translation="MKTTLGIEFEPFFPQISHRAKIGCAKYDLSTGEGVAMEQWYLNM
                     GEVPGTPLSQIVGIYSNVKPEDRECLKTSLSRLVHGETDHDQGEVRVKDGEGWKWVRL
                     DIMEAGLEKSSPILLLMNYDISELKAMEERMLKAEKSERLKSSFLANISHEIRMPLNA
                     IVGFSSLLGDEEDGELRQEYINLIQTNNELLLGIVNDVLDLAKLESGTMTFDFMEFDL
                     RQLIVETVASFQIKVPRGVALTYPASLDSFLLRSDRIRLKQVLGNFITNAIKYTSIGS
                     IILSYQAMENEVLLSVTDTGEGMSEEIKLHVFDRFYKGRNQKQGIGLGLSICQNIIER
                     LGGRIGVSSEQGKGSCFWCTLPIFPPKDTY"
     gene            1561..1950
                     /locus_tag="ACZPB4_07335"
     CDS             1561..1950
                     /locus_tag="ACZPB4_07335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator
                     DNA-binding domain-containing protein"
                     /protein_id="HIR1098068.1"
                     /translation="MERYLIIKTRDELLRIKIGQILYFEADRNYTKLLLSNGIQFTFA
                     INIGKIEEILEKQVAGCNKILMRVGKSHIINKNHILQINLPKQRLLLLTEEGKPKELV
                     ISKDPLKVLKDNLEKEMGKPQEEEEKE"
     gene            1955..2608
                     /locus_tag="ACZPB4_07340"
     CDS             1955..2608
                     /locus_tag="ACZPB4_07340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FHA domain-containing protein"
                     /protein_id="HIR1098069.1"
                     /translation="MIIKIGKAKDNDFIANDPHVSRHHARLIREDGGNLLLEDTGSTN
                     GTFVNGAQIVKKRVTPTDHIRLGDSYVLNLSEVLKYNNDYSDEFAALKKVYDDYIQAK
                     VKIQSSNQFKTRLFQSLPFALPGIVGVVIGFLGKGSPELFGISLLITICAPTVGIYLG
                     AKQSAKIPQQLQDIANQFKIDYVCPKCGTFLGEIPWESLKNRKQCPVSSCKAKWVRE"
     gene            2751..3005
                     /locus_tag="ACZPB4_07345"
     CDS             2751..3005
                     /locus_tag="ACZPB4_07345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098070.1"
                     /translation="MQEEEYTFVTLDGNDVMPADAVIIDVEGGGVDLGDAIVIDDSSI
                     ESFDHSDFITLADDTVMLSDTDMMDLYSTDMDGADISFIV"
     gene            3002..3517
                     /locus_tag="ACZPB4_07350"
     CDS             3002..3517
                     /locus_tag="ACZPB4_07350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FHA domain-containing protein"
                     /protein_id="HIR1098071.1"
                     /translation="MIAVKCPHCHVGLKVAEGKIPLGITSFKCPKCKEPIPLSLLSEK
                     SNHQEVDSDTILVTPVKTGIGRLTVLPDADTPEQAFPLHEGKVVIGRKSNASQATMPI
                     ITADRTMSREHICIEVKKDSKGGYKHFLTDNNSKNHTLYNNSYLENGEVVVLNDNDEI
                     IIGRTVLRFNE"
     gene            3530..4333
                     /locus_tag="ACZPB4_07355"
     CDS             3530..4333
                     /locus_tag="ACZPB4_07355"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PP2C family protein-serine/threonine
                     phosphatase"
                     /protein_id="HIR1098072.1"
                     /translation="MIITIGKPCAITEKGGRSNNEDSIYPLPEQVTLDQKLFMVCDGV
                     GGAEKGEVASSLACESIQTFFSTFLKDDPTPEFIHKAVHYAEVCFDSYVQEHPEAMGM
                     ATTLTMAYIASSGIVLAHIGDSRIYHLRKGEILYQTEDHSLVNSLVKLGKITPEEALT
                     HPQRNVIIRAIQGTHTPTEADIITLNDIQPDDFLFLCTDGVLERLKNEKIAEIFNGRL
                     SVPEIKDALMEACDGKTRDNFSFYIITIQKVEDSMGFKQNILSFLYSFI"
     gene            4375..6168
                     /locus_tag="ACZPB4_07360"
     CDS             4375..6168
                     /locus_tag="ACZPB4_07360"
                     /EC_number="2.7.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008157763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine-protein kinase"
                     /protein_id="HIR1098073.1"
                     /translation="MNLPDGHLLQNGKYRLTHVVGQGGFGITYRGVWYTEVKGSLGTV
                     KTEVPICVKEYFFKDYCYREPGSQAVKVHSETGKVLFNKFKEKLIKEAKILSEVHHPY
                     IVNVLEVFEENNTAYIAMEYISGFSLKYMLEKNGILPEATVLKYVRQIGEALQFVHDK
                     SILHLDIKPSNILIDKNGNARLIDFGVSKRYDIEQEETSTTMLTLSKGFASIEQYDNE
                     GTQVFSPRPDIYSLGATMYNLLTGTIPTESILRAARPLRNPSEINAAISPKTEAVIIK
                     AMQIIPADRFETVGEMLASLDFSQAEKEVQVVPSPSPEIVNEETTVVYSSPVDSKLVG
                     SDDEETVVNVANPPAVEPITEKNNSRKKIIPIGIAIFVVVGSATALLVHSNRPTKEVV
                     ESIDLPSAVEPDSNVSKEVEMPDHPVLHTEPPISEIKKAEKQEPKVEEKRPMETEHTI
                     EENVLPDQPSENEMNEKYNSLIASGKEKMAKADYSGAKKDLSEAKDTKLTEEVVRLII
                     ACDEKTEEKRIADKKALYEEKMAFGRYKIVRKKSNNRYGAIDSKAEERIPCKYLSVGI
                     ADNGRAFEREDNLFDIYNSDGSLISEGLTYY"
     gene            6210..7166
                     /locus_tag="ACZPB4_07365"
     CDS             6210..7166
                     /locus_tag="ACZPB4_07365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098074.1"
                     /translation="MKRLWILMICAVFPLGLLAQQRTEYNRKGDEAMKRLDYSDAKMW
                     YEEGVSQCDAYSIDQLTTIWLSNERMRPSMRSLMNKCLNCLTVKATEDDPDAISKLII
                     YYSEGIGTPKSEELATYWKEYQEILLKPAEPAAQPIDSAAVSPKKRMEFFAGYSYSIE
                     SPYGITVGGMGQRFGWYVRFKTNMSFMNYTDECNNQGQIIKFSNSEGESYELNTGKSS
                     KTNSIAGTAGLIVKCFPWLYASVGLGYGERALLHSFTTHSYENYDSTREVWCRNIDSS
                     YKGVAAEVDLMMKITNSVFISVGCNTVNFKYLDLNAGLGVFF"
     gene            7179..9341
                     /locus_tag="ACZPB4_07370"
     CDS             7179..9341
                     /locus_tag="ACZPB4_07370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Kelch repeat-containing protein"
                     /protein_id="HIR1098075.1"
                     /translation="MKHIYSLFSILFAALLMAGCVNDPDIDGGIRNAKKPSVKTDEIL
                     KSTASSVTVSGEVLQENGAPVTEAGFCWSTESTFTVIEKNKKAVSKRKVKYEATIEGL
                     TNDLDYYIRAYAINAVDTAYGEILPFKTKDGLGSVKTLFPVNVMSTSVQCGGMITKQG
                     EAEIEERGIYLMLNPEPSASDSTIRIDMEADSFYCTISDLKPETTYYVRAYAKSKYGE
                     YNGAKVETFKTTNGRPVLDDNKFKKIATEFTYAEFSMEIISEGDSPITACGFCFSTDK
                     SPTIENGDTIICGAGIGEFAGKIYDMQQQKGYYVRAYATNALGTTYSAGEGIHTILES
                     ELPTVNTKEVSTIKNGTAWVGGEVLAEGASPVTEAGVCWGTSPSPAFGNCEGAVALSS
                     GTQAFTGTIKELRGGTSYYLRAYAKNKNGIAYGEEVRFQTPDIFGVGARFEGAFRIPG
                     STSFCTLANSTGFLLGGDTGREYTDEFWGYMTSKKEWLPLRSQPEKLSGQACFSIGFG
                     LWTFGGLDNTGKICDSLYVYSTSDNSWSAVQTDQQRPKGMYRAACCRMEDQAFLIGGR
                     RGNELIDEVWTYEPSAFVWSKKSNFPIKQYGGISVVIGDRIYAGLGIINKADPSLEYT
                     TQFWSTDKNAVAWEKEASFPGRMLLCAIAYGNYVYGVDGDGYIWRYDPDSQNWSQKSQ
                     LPAANRSVHCMYVLDNYIYIGLGNASNSLISYDPTWDN"
     gene            9344..10240
                     /locus_tag="ACZPB4_07375"
     CDS             9344..10240
                     /locus_tag="ACZPB4_07375"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HIR1098076.1"
                     /translation="MNRTAILEQIQKNVERLSAPDLPEYKYIPLHQKPSPSVATLHEI
                     MRLLRTVIFPGFFGTEQEAQLGSIQYYTGVYLEKIYDLLQEQIYNGLCFEVERCCDSK
                     DRASDISIAFINRIPHIKYLLSTDVKAILDGDPAAKSVSEIIFCYPAVYALLHQRVAH
                     ELFELGVPVLPRIITEMAHSQTGIDIHPGAQIGEYFSIDHGTGIVVGQTAIIGHHVRL
                     YQGVTLGAKSFTLDEEGLPIDLPRHPIIEDYVTIYSNASILGRITIGRGSIIGGNIWL
                     THSVPPNSKISQSRVEEKFTEI"
     gene            10315..10713
                     /locus_tag="ACZPB4_07380"
     CDS             10315..10713
                     /locus_tag="ACZPB4_07380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(2Fe-2S) ferredoxin domain-containing protein"
                     /protein_id="HIR1098077.1"
                     /translation="MNKVKTLDDLKKMRESLRASLDLREKSNTPDQLVQIKVSMATCG
                     IAAGAKEIMSYFIEVLDRQKIDALVTQTGCMGYCYAEPTIEIKLPGQEPLVFGYVDKA
                     KVEEIIDKYIRKGILVDGIIPVTYTTVKPE"
     gene            10735..12525
                     /locus_tag="ACZPB4_07385"
     CDS             10735..12525
                     /locus_tag="ACZPB4_07385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010803102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-ubiquinone oxidoreductase-F iron-sulfur
                     binding region domain-containing protein"
                     /protein_id="HIR1098078.1"
                     /translation="MAQYTNYILVCGGTGCRASQSEQIIENLRAAVEQYGLEDTQVIR
                     TGCFGFCEKGPVVKMIPDNTFYVQVQPSDTDEIVREHLVKGRKVERLLYMNPENRELV
                     PDSKHIGFYKKQLRIALRNCGFINPENIDEYIARDGYVALGKALVEMTPEEVIKEIMD
                     SGLRGRGGGGFPTGLKWQITRKVQAPQKYVVCNADEGDPGAFMDRSILEGDPHSIVEA
                     MAINGYCTGASKGLVYIRAEYPLAVERLKIAIRQAKEYGLLGENIFGTDFSFDIEIRY
                     GAGAFVCGEETALIHSMEGLRGEATVKPPFPSEHGYKGCPTNVNNVETYANIPVILLR
                     GAKWFSSIGTEKSKGTKVFALAGKVNNVGLIEVPMGTTLREVIFGIGGGIKDGKKFKA
                     VQTGGPSGGCLTEKHLDLPIDYDNLLAAGSMMGSGGMIVMDEDDCMVAMAKFYLDFTV
                     EESCGKCAPCRIGNKRLHEILQKITSGNGTEEDLTRLRNLAMVIKDTALCGLGQTSPN
                     PVLSTMDNFYDEYLAHVREHRCPSHQCRELTQYFINPEKCKGCTLCARVCPVHAITGG
                     RKIPHIIDPQACIRCGTCMEKCKFGAIYVH"
     gene            12540..14330
                     /locus_tag="ACZPB4_07390"
     CDS             12540..14330
                     /locus_tag="ACZPB4_07390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent [FeFe] hydrogenase, group A6"
                     /protein_id="HIR1098079.1"
                     /translation="METIQLIIDNKEVEVPRGTTILDAAKSVGIHIPTLCYMKLEDLH
                     YENNPGACRICVVEIEGRRNLAPSCKMECTEGMVVRTHTPRVMNARRTVMELILSNHP
                     AECLTCSSNGHCELQKIAHDLGIREIRYKGEMSTFTIDRSPSIVRNMNKCIMCRRCET
                     MCNTIQTVGALTAVNRGFNAAVSTAFERDMAGSTCSYCGQCVSVCPVNALSGRNTQQP
                     VLDALADPTKIVIAQTAPAVRTALGRDFGYEPGTLVTGKMVSALRQLGFDYVFDTDFA
                     ADLTIMEEGTELLHRLGSYLNGDKEVKIPLMTSCCPGWVSFVEQHFPELRDHLSTAKS
                     PQQMFGAIAKSYFAEKLGVDRKDLVVVSIMPCLAKKYEASRPEFSVEGNPDVDYSIYT
                     RELARLIRYANIDFNELPDGEFDRPLGESTGASVIFGTTGGVIEAACRTAYELYTKKN
                     LDKVDFEELRGLEGIRSATIDFNGTSVKIGIAHGLGNARKLIEEVKNGTSPYHAIEVM
                     ACPGGCIGGGGQPFHRGRMEVLRRRAAALYREDANKPLRKSHENPYIQQLYSEYLGEP
                     CGPKAHKLLHTHYIDRKEVIGMYIETEKSK"
     gene            14334..14822
                     /locus_tag="ACZPB4_07395"
     CDS             14334..14822
                     /locus_tag="ACZPB4_07395"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoE family
                     protein"
                     /protein_id="HIR1098080.1"
                     /translation="MNEIHLPKTKVAELHAICAERNNDPGELINILHAAQGLFGYLPP
                     EVQQVIAAELNIPVSRVYGVVTFYSFFTMTPKGKYPISVCLGTACYVRGAENVLEEMQ
                     RQLEIKVGETTPDGLFSLDCLRCVGACGLAPVVMIGGKVYGRVTPEKVRDILSDYYLK
                     EQ"
     gene            complement(14896..15867)
                     /locus_tag="ACZPB4_07400"
     CDS             complement(14896..15867)
                     /locus_tag="ACZPB4_07400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HIR1098081.1"
                     /translation="MSEIKNIGSRCKCPVSLLWISLLLVGFASSIFAAKDYSIETIPN
                     VRLSNRLNHVSNPDGIITPDDAARINQLLNVVEDSLGIEVAVVAVNSIGDQDARMFAT
                     DLFKHWGLGQKSKDNGLLIQLVTEPSQRSVVFETGYGIEGVLPDAICYRLQQRYMMPD
                     LKAGNYSAGMLKGVMAVTKYLMSSDYERAGMTGNRSSSSSDDDFMWIFVVGIIGMIGF
                     SAFIAYLKYRPKACPRCGKKTFVYMGQQVIREATRFSEGLAEDVYRCKSCGYTEKKNR
                     TIDRIHRGGGGPIIMGGGGGFGGFSGGGGGGSWGGGSSGGGGSISRF"
     gene            complement(15882..16469)
                     /locus_tag="ACZPB4_07405"
     CDS             complement(15882..16469)
                     /locus_tag="ACZPB4_07405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HIR1098082.1"
                     /translation="MFKNKVVWIIIAIVAILFFWVKGVYNNMVTQDEGVKTAWSQVEN
                     QYQRRMDLIPNLVNTVKGYAAHEKETLEGVVNARAEATKTTIDPSNLTEESLKKFQSA
                     QGELGNALSRLMLVLERYPDLKANQNFMELQAQLEGTENRISVERKRFNEVAQSYNTY
                     IRQFPNNILSGMFGFQSKAYFAAESGAEKAPKVEF"
     gene            16798..18177
                     /locus_tag="ACZPB4_07410"
     CDS             16798..18177
                     /locus_tag="ACZPB4_07410"
                     /EC_number="1.11.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c peroxidase"
                     /protein_id="HIR1098083.1"
                     /translation="MRKTIYAKMTALPVGLCALAFAVTSCGSSEYKKFADNEGKQVAS
                     ILRENDCLACHSENAPLPFYGNLPLIGPVVQADMKEAVHYVDLTAMVEALENGQPVSE
                     VDLAKVENTALSGSMPPAKYSHMPMHWGTSLDDNEKAVIISWAKNVRKDRFTTETVAE
                     EFKNEPLQPLMKSLPTDPAKVELGFALYHDTRLSADNTISCATCHGLNTGGVDRKQYS
                     EGINGQFGGVNAPTVYNAALNFVQFWDGRAADLKEQAAGPPLNPVEMGCTSFDQICEA
                     LAQDKDFTKKFTEVYPEGYSQSTITDAIAEFEKTLLTPSRFDKYLMGDKNALTAEELE
                     GYQLFKDNKCATCHVGVNVGGQSYEFMGIKNSYFDYRNTGLTDGDNGRYAVTKKESDR
                     HKFKTPTLRNVMLTYPYMHDGTVASVEDAIRIMHEFQIGKEINDVEVEKIVVFLGTLN
                     GEYNGKMLQ"
     gene            18195..18656
                     /locus_tag="ACZPB4_07415"
     CDS             18195..18656
                     /locus_tag="ACZPB4_07415"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008932 - lytic endotransglycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="septal ring lytic transglycosylase RlpA family
                     protein"
                     /protein_id="HIR1098084.1"
                     /translation="MSFRLFYILLIFAAVKCGEGIWAQEEGLASYYHHRFHGRKSSSG
                     RVHDKEELVAAHRTYPFGTFLRVTNLENMKSTIVCVTDRGPRYRKRIIDVSASAAEIL
                     DFIDKGVAKVRIEVVPGPLDLRYLDLIYPKIPYLDIDYLRPDPPYRVKFTK"
     gene            18667..19599
                     /locus_tag="ACZPB4_07420"
     CDS             18667..19599
                     /locus_tag="ACZPB4_07420"
                     /EC_number="4.1.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004300450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0048040 - UDP-glucuronate decarboxylase
                     activity [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA];
                     GO_process: GO:0042732 - D-xylose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucuronic acid decarboxylase family
                     protein"
                     /protein_id="HIR1098085.1"
                     /translation="MKQILITGGAGFIGSHLCARLLEEGNEVICLDNYFTGSKENVIP
                     LLKNPHFELIRHDVSIPFQAEVDEIYNLACPASPVYYQIDPIQTIKTSVLGAVNMLGL
                     AKRVNAKILQASTSEVYGDPMIHPQPESYWGNVNPIGPRSCYDEGKRCAETLFMDYHR
                     QNKVRIKIIRIFNTYGPNMSTNDGRVVSNFIIQALQNKDITIYGDGNQTRSFQYVDDL
                     IEGMIRMMNTSDDFTGPVNIGNQGEFSMNELAKIVIRLTNSSSKIVYRPLPGDDPKQR
                     KPDITLAKEKLDGWEPTVCLEEGLKKTILYFKSL"
     gene            19690..20949
                     /locus_tag="ACZPB4_07425"
     CDS             19690..20949
                     /locus_tag="ACZPB4_07425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HIR1098086.1"
                     /translation="MDRRVTLLLFLSLLFSGAKASVVSLSLKESEQRFSEHNLEVIAE
                     RYNIDIAEAQVVQAKLFENPVVSLEQNVYNRLNGRYFDFGKQGETIVEVEQLIYIAGQ
                     RNKRVRLEKINKEMALYQFEEVLRTLRSELKEKFIALYFTRKSQSIYDREIDSLAHLL
                     VVLKEQNEKGNVSLLEKSRIEALLLSLRQERNDIANQVISLQGDMRLLLGISGNDTFE
                     PIFDESVLNQIDMDSVPFSELTSLLYERPDLKLAQASVKASEADVRLQRSLAFPEVSV
                     KGTYDKAGNFINDYWAIGLSVSLPIFNRNQGNIRAAKISVAQKAHKEEYARRQAENEL
                     FTSYARLEKAIQLYRSSNYGLEKDFALIIKGVNSNFQKRNISLLEFIDYYETYKTTCL
                     QLYQTQKEVLLALEEVNTVTGSHVFNY"
     gene            20966..22051
                     /locus_tag="ACZPB4_07430"
     CDS             20966..22051
                     /locus_tag="ACZPB4_07430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HIR1098087.1"
                     /translation="MNKHLITCILLVPLVCSCGKQATTSVDTREPLLLNDSLQEIITL
                     DTVRDTPLTNELLLNGRVSFNPERVAHVYPMFGGNVTSVHAEVGDYVGKGDVLAVIRS
                     GEIADIDKQRKEAEHQLAIANRNLEATQDMARSGMASDRDFLQAQQEQADADAETKRI
                     QEMYSIYNITDPSTYVVKAPVSGFIIDKNINRDMQIRSDQGEEMFTISGLDDVWVMAD
                     VYEGDISKVKEGATVRITTLAYKDMEFTGTIDKVYHMLDRESKTMSVRVKLRNEKYML
                     KPGMFTNVYVQSAVKGESMPCVNAHAVIFEDGKEYVVYVSKEGYLQMREISVYKQTEK
                     FCYLRSGLKDGDRIVDRNALLVYNELK"
     gene            22061..25186
                     /locus_tag="ACZPB4_07435"
     CDS             22061..25186
                     /locus_tag="ACZPB4_07435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004295724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HIR1098088.1"
                     /translation="MHTFIDNIITFSLRNKFFIFFCTTIAVIAGITSFIHTPIDAFPD
                     VTNTKVTIITQWPGRSAEEIEKFITIPIEIAMNPVQKKTDIRSTTLFGLSVINVMFED
                     KVDDFFARQQVYNLLNDADLPEGVTPEVQPLYGPTGEIFRYTLRSDKRSVRELKTLQD
                     WVIERKLRAVPGVADIVSFGGEVKTFEVSVNPNQLISYGVTTLELYDAIAKSNINVGG
                     DVITKSSQAYVVRGIGLINDVKEIENIVVKNINGTPILVKHLATVHESSLPRLGQVGR
                     MEEDDVVQGIVVMRKGENPGEVIAALKDKIKDIQQNALPEDVRIVSFYDRENLVDLAV
                     KTVTHNLAEGILLVTFIVLIFMADWRTTVIVSIIIPLALLFAFICLRAMGMSANLLSM
                     GAIDFGIIIDGAVVMVEGLFVALDRKAREVGMPAFNLMSKMGIIRHTAKDRAKAVFFS
                     KLIIITALVPIFSFQKVEGKMFSPLAYTLGFALLGALIFTLTLVPVLSSMLLKKEVRE
                     KHNPFLAWINRKSIGIFDWCHARKKRTITFATLVAAVGIWCFTLLGSEFLPQLNEGSI
                     YIRATLPQSISLDESVTLANQIRRKLAAYPEVRQVLSQTGRPNDGTDATGFYNIEFHV
                     DIYPEKEWESERSKAGLIEKMQEDLAIYPGVDFNFSQPISDNVEEAASGVKGSIAVKV
                     FGKDLYESEKKAVEVFKVLETVDGIEDLGVIRNIGQPELRIELNESRLARYGVAKEDV
                     QSIIEMAIGGKNASLLYEDERKFNIMVRYESAFRRSENEIGKILVPAKDGSMIPIREL
                     ADIHTITGPLIIYRDNHARFCAVKFSVRGRDMGSAVAEAQRKVERQVKLPEGYTLKWT
                     GDFENQQRATKRLAQVVPVSIAIIFVILFVLFGNARDAGLVLLNVPYAAVGGILALLI
                     TNFNFSISAGIGFIALFGICIQNGVIMISDIKNNLRERHPLEDSIKMSVKSRVRSVLM
                     TASMAAIGLLPAALSHGIGSESQRPLAIVIIGGLIGATFFTLFVFPLMVEAFYRRMLY
                     DKNGKLVQRRL"
     gene            25351..26028
                     /locus_tag="ACZPB4_07440"
     CDS             25351..26028
                     /locus_tag="ACZPB4_07440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HIR1098089.1"
                     /translation="MAKILLVEDEINIASFIERGLREFGHEVYVAYDGAAGWELTQKN
                     DFQLLILDIIMPKMNGLQLCKQYRQRFGYHAPVIMLTALGTTEDIVSGLDAGADDYLV
                     KPFSFQELEARIKALLRRSGNESVHMALRCGDLVLDPPSHRAIRNGQVIDLTVKEYRL
                     LEYFIQNQGTALSRMNLLKNVWDKDFDTNTNVVDVYVNYLRTKIDKDFEPKLIHTVVG
                     VGYMMEA"
     gene            26025..27200
                     /locus_tag="ACZPB4_07445"
     CDS             26025..27200
                     /locus_tag="ACZPB4_07445"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1098090.1"
                     /translation="MKTGNKIALFYSAITIGVIAVVTLVFYLVSTSYISRLYYSYLTE
                     KAYATAQKHWEKDETDDESYARIQQRYEETLPVATEILLNADSLETRQVLSRYLDATQ
                     VRSLYQEDIVHFKHDTQMGAALYYPDNEGNFIVIVLSGNQYGMDIQHRIGWLLLGLIL
                     VSSVLIYFVGRLYATRMVDRIDAAYQSEKAFISNASHELNNPLTAIQGECEISLLKER
                     SPEEYQAALRRIATETSRIIQLIKHLLFLSHGDKEIQKSAMETIFLADFLMQFSSARI
                     SFSPDNFSYMIRANPYLLKIAIKNILSNACKYSNDKPVEMRLRGSILTISDRGIGIPP
                     EELKRIFQPFYRASNTREYAGHGVGLSLSLRILSTYGAKVNIISDLGVGTSVEIDFG"
     gene            complement(27151..29109)
                     /locus_tag="ACZPB4_07450"
     CDS             complement(27151..29109)
                     /locus_tag="ACZPB4_07450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HIR1098091.1"
                     /translation="MNQSHKRSFIAVLIFIGFLLFMAFWGIDLILGAYAGHKLSKLAE
                     RHHLDIRYDKIRLMGLSTVRMEGLTVIPVDADTLIHADRLQAKLELGRLLLLTPSIES
                     VQADNLHIHFIKKGERANFDFLYKPSNHPGEPVETAVDDKERDYARKAERSLSLLFNL
                     LPGNALVHDLCVSYSNKGDELILEIPELNLANNQFSTHINSTENGVRSEWICEGSLSD
                     KERLVKARLYADEHTKIPLPFLEYRWGASVRFDTLAFELKGPKIEEDIQSLLGSAYVS
                     GLTIHQERISPDTVLLDKGSIHFRTNIGKNYIELDSVSDIRFNHLDFHPYLKIVKDTS
                     WQITASVNKRDFPADQLFSSLPKGLFYNLEGLRTEGTLSYHFRLDLDFGQVDSLILES
                     TLKAKGFQILAYGNTDLRKMNEPFEYTVYEQGEPVRSFEIGPANPSFRPFNAVSRYLP
                     LAIMQSEDAGFFYHNGFIPSAIRESLIQDIKERRFARGGSTLSMQLVKNVFLSRNKTI
                     ARKLEEMLIVWLIESNHLTSKERMFEVYLNIAEWGPMIYGAAEASRYYFAKEPSQLNL
                     AECIFMASIIPKPKQVRYCFDGLRLKPYYEDFYRVILDRLVDRGLISSEEAVGVTPES
                     VEITGPAKEYLTATQSRSPRSSQPLDQK"
     gene            29222..30220
                     /locus_tag="ACZPB4_07455"
     CDS             29222..30220
                     /locus_tag="ACZPB4_07455"
                     /EC_number="1.1.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004326528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008720 - D-lactate dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0070404 - NADH binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacid dehydrogenase"
                     /protein_id="HIR1098092.1"
                     /translation="MAYKIAFFGAKPYDIASFDKINERYEFDIRYYKGHLNINNVVLT
                     QGVDAVCIFVNDTADAAVIDALVANGVKLLALRCAGFNNVDLNAARGKLPVVRVPAYS
                     PYAVAEYTLALMLSLNRKIHRAYWRTRDGNFSLNGLMGFDMHGKTAGIIGTGKIAKIL
                     IHILKGLGMRVLANDLYPDEKFAKEEGITYVSLDELYKESDIISLHCPLTDQTRYLIN
                     DDSIAKMKDGVMIINTGRGLLIHTNALIEGLKTKKVSAAGLDVYEEEGDYFYEDKSDK
                     IIDDDVLARLLSFNNVIVTSHQAFFTKEALHNIAETTLRNIKDFEEGRPLVNEVTK"
     gene            30322..31158
                     /locus_tag="ACZPB4_07460"
     CDS             30322..31158
                     /locus_tag="ACZPB4_07460"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HIR1098093.1"
                     /translation="MEIDSQTGLVLEGGGMRAIFTVGVLDYFMDHDIWFPYTIGVSAG
                     ASNGISYASRQRGRSRFSNIDLLKKYNYIGLRHFLRGRGYIDLNFLFYVYPDLYYPLD
                     YDTYFKSKDRFVMVTSNCLTGKAEYFEEKKDKKRLVDICKASCTLPILCPITYVDGIP
                     MVDGGVCDAIPIRRAIADGFSKNVIILTRNKGYRKEEKDFYLPGFIYNKYPAIREQLR
                     LRYRRYNEVLDYIDQLEAEGKAFVIRPQSPIKVGRTGSDTKKLEELYEEGYECGKQIT
                     QL"
     gene            complement(31199..>32476)
                     /gene="thiC"
                     /locus_tag="ACZPB4_07465"
     CDS             complement(31199..>32476)
                     /gene="thiC"
                     /locus_tag="ACZPB4_07465"
                     /EC_number="4.1.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /protein_id="HIR1098094.1"
                     /translation="IITPEMEYVAIRENQQIEALGLKSYITPEFVRKEIAAGRAIIPA
                     NINHPEAEPMIIGKKFLVKINTNIGNSALSSGIDEEIEKAIWSCKWGGDTLMDLSTGD
                     NIHETREWIIRNCPVPMGTVPIYQALEKVNGKVEDLSWEIYRDTLIEQAEQGVDYFTI
                     HAGLLRKHVELTATRLTGIVSRGGSIMAKWMQLHDEENFLYTHFAEICEILKAYDVAV
                     SIGDGLRPGSIYDANDAAQFAELHTMGELTKIAWEQFVQVIIEGPGHVPMNKIHENMK
                     EQQYACHGAPFYTLGPLTTDIAPGYDHITSAIGGAQIAWHGTAMICYVTPKEHLGLPN
                     KEDVRNGVVAYKIAAHAADLAKGHPGAQVRDNALSKARFDFRWKDQFNLSLDPERALQ
                     YYKESAVTDGEYCTMCGPNFCAMRLSKDLQGCK"
BASE COUNT         9082 a         6906 c         7955 g         8533 t
ORIGIN      
        1 gcggcgcaag cggctctaga agactaatca aggggttgat ttttaatagt ttaagcacac
       61 ggtagacagg agggtggatt gagtgatcaa tctaccctct atttttttat agtcatatgg
      121 tataatctta tatatcagga tattgaagtg gaggggaagg caacaaaacg actagtttaa
      181 tcgttcgttt taattagtcg tttgcaaata tcgcaaaaaa tatttactta tgaaagtcaa
      241 aaagacttta gaatataatt ttgatgcggt ttttggggta ttttactaaa cctatatgtt
      301 ccctataaaa taatcgatat aaacgactaa ttaaaacgaa cgattaattc attcgttttt
      361 tatggctaaa ccctcttttt gcataaatat aatgagaacg gatatatatg aaaacgacat
      421 taggcataga gttcgagcct ttttttcctc agataagtca tcgtgccaag atcggctgcg
      481 caaagtatga tttgtccact ggggaaggag tggcgatgga acaatggtat ctgaatatgg
      541 gtgaagttcc gggaactcca ttgagccaga tagtaggcat atattccaat gtcaagccag
      601 aagaccgtga atgcttgaaa acttccttga gccgacttgt ccacggagaa actgatcatg
      661 atcaagggga agtccgggtc aaggatggcg agggatggaa atgggttcgt ctggatataa
      721 tggaggcggg tctggagaaa tcaagcccca tcctattact gatgaattat gacatatctg
      781 aactgaaagc gatggaagaa cgaatgctga aggccgagaa atcagagcgt ttgaaatcct
      841 cctttttggc aaacatcagc catgagatcc gcatgccatt aaacgctatt gtcggattct
      901 cttctctttt aggggatgaa gaggatggtg agctaagaca agagtatatt aatcttattc
      961 agaccaataa tgagttatta ttgggtatcg ttaatgatgt attggatctg gctaagctcg
     1021 agtctggtac catgaccttt gatttcatgg aatttgatct aagacaactt attgtagaaa
     1081 cggtagcttc tttccagatc aaagtaccga gaggagtagc tttgacctat ccggcatctt
     1141 tggattcctt tttattacgc tccgaccgta tccgtttgaa acaagttctt ggcaatttta
     1201 taacaaacgc aattaagtac acctctatag gtagcatcat cttgtcatat caagccatgg
     1261 agaacgaagt tctgttatcc gtgaccgata cgggggaagg aatgtcggag gaaataaaac
     1321 ttcatgtgtt cgatcgtttt tataaaggac gaaaccaaaa gcaaggcata gggcttggac
     1381 tttctatctg ccaaaatata attgaaaggc tgggagggcg tatcggtgtc tcttctgagc
     1441 agggaaaagg ctcttgtttt tggtgcactt taccaatctt tcccccaaaa gatacctatt
     1501 aaataaagaa aataccgtat atttgttttt gaaagagaaa cgaaaaaaca atttctacgt
     1561 atggagcggt atttaattat aaaaacaagg gatgagttgt tgcgcattaa gattggtcag
     1621 atcctttatt ttgaagcaga caggaactat acgaaactat tgttgtcaaa tggcatccaa
     1681 tttaccttcg ctataaatat cggaaaaata gaagagatct tagagaagca ggtcgctggt
     1741 tgtaacaaga tattaatgcg tgtcggaaaa agtcatatca taaataaaaa tcatatctta
     1801 caaataaatc tccctaagca gcgtttatta ttattgacgg aagagggtaa gcctaaagag
     1861 ttggtaatat ccaaggatcc gttgaaagtg ctgaaagata atcttgagaa ggagatggga
     1921 aagcctcaag aggaagagga aaaggaataa gacgatgatt ataaagatag gaaaagcaaa
     1981 agacaacgat tttattgcaa acgatcctca tgtaagccgc catcatgccc gtctgatacg
     2041 tgaggatggt ggcaacttat tattggagga tacgggatct actaacggta cgttcgtgaa
     2101 tggtgcccag atcgtaaaga aacgtgttac tcctacggat catattcgct tgggggatag
     2161 ctatgtatta aatctttccg aggtgcttaa atacaataat gattatagcg atgaatttgc
     2221 cgcattgaaa aaagtctacg atgattatat tcaagcaaaa gttaagattc aatcctctaa
     2281 tcagtttaag accagattat ttcaatcctt accatttgct ttgcccggaa tagtgggggt
     2341 cgtgataggc ttcttaggga aaggtagccc ggagctattc ggcatcagcc tcctgataac
     2401 gatttgtgcc cctacggtag gaatctatct aggagccaag cagtcggcca agattcccca
     2461 gcaattgcag gatatcgcca atcaatttaa gatagactat gtttgcccga aatgtgggac
     2521 attcttgggt gagatccctt gggaatcatt gaaaaaccga aagcaatgcc cagtttcttc
     2581 ctgtaaggcc aaatgggtga gagaatgagc cttttctttt cgtatagtga aacagcctct
     2641 tttgtacatg aaacccaaat gtttgattat aagagagaat aacaagttta ttaatccatt
     2701 gctttttgta cttttgtttt cggaatatta atatattagg aacaaaggtt atgcaagaag
     2761 aggaatatac attcgtaact ttagacggca atgacgtcat gccagcggat gctgtcataa
     2821 tagacgtgga aggaggaggt gtcgacctag gcgacgccat agttatagac gatagtagca
     2881 tcgagtcttt cgatcattca gactttataa cattggcgga cgatacggtt atgctttccg
     2941 atacagatat gatggatctg tactctacgg atatggatgg cgcagatatt tcgtttatcg
     3001 tatgatcgca gttaaatgtc cacattgcca tgtaggatta aaggtagccg aggggaagat
     3061 tcccctcggc attacctcct ttaagtgtcc gaaatgcaaa gagcctattc ctttgtcctt
     3121 attatccgag aaaagtaatc atcaggaagt cgattccgat acgattttag tgacacctgt
     3181 caagactgga atcggcagac tgacggttct tccagacgcc gatacacctg aacaagcgtt
     3241 tcctcttcac gaagggaagg ttgtcattgg ccggaagtcg aacgcctcac aagctacgat
     3301 gccaattatc acggctgatc gcacgatgag tcgcgagcat atttgcattg aggtgaaaaa
     3361 agattcaaaa ggtggatata aacatttcct taccgacaat aatagtaaaa accatacgtt
     3421 atataataac agttacctag agaatggcga ggtggtcgtg ctcaatgata atgacgagat
     3481 tattattggt cgcaccgtct tacgttttaa tgaataaaac tcatttgtta tgattataac
     3541 gatcggtaag ccatgtgcta ttacggaaaa aggaggcaga tcgaataacg aggattccat
     3601 ttacccgctt cccgaacaag tgacccttga ccaaaaattg tttatggttt gcgatggtgt
     3661 gggtggagcc gagaaagggg aggtagccag ctcattagct tgcgagtcca tacaaacttt
     3721 cttttctacg ttcctaaagg atgatcccac gccagagttt atccataaag ccgtacatta
     3781 tgcggaagtc tgtttcgact cctatgttca agagcatccg gaagcgatgg gtatggctac
     3841 tacgctcacc atggcctata tcgcttcttc cggaatcgta ttggctcata tcggagatag
     3901 ccggatctat catctgagga agggggagat tttatatcaa acagaagatc attcattggt
     3961 aaattcgttg gttaaattag gtaagatcac tccggaagaa gcgttaaccc acccccagcg
     4021 gaatgtgatt atccgggcta tacaaggcac tcatactcca acagaagcgg acattattac
     4081 cttgaacgat attcaacccg acgatttcct ctttctttgt acggacgggg ttcttgaaag
     4141 actgaagaat gaaaagattg cagagatatt taatggtcgt ttatctgttc cggaaataaa
     4201 ggacgctctc atggaagcct gtgacggcaa gactcgggat aatttttctt tttatatcat
     4261 aactattcaa aaagtggaag atagcatggg ttttaagcaa aatattctct cttttcttta
     4321 ttcttttata taaataacgt acttttggca gattaaatgg aattattcaa ggttatgaat
     4381 ctgccagacg gacatcttct tcaaaacgga aaatacagac ttactcatgt ggttggtcaa
     4441 ggtggttttg gcataaccta cagaggagtt tggtacacag aggttaaagg atctttaggt
     4501 accgtaaaga cggaggtccc tatctgtgtc aaggaatatt tcttcaagga ttattgttat
     4561 agagaacccg gttcccaagc cgtaaaagta cattcggaga cgggaaaggt cttatttaac
     4621 aagttcaagg aaaaactgat caaagaggca aagatcctat cggaagttca ccatccctat
     4681 atcgtaaacg tgttggaggt tttcgaggaa aacaatacgg cttatattgc catggagtat
     4741 atttccggct tctcgctaaa atatatgctt gagaaaaacg ggatattgcc cgaagctacg
     4801 gtccttaaat atgtacggca aattggcgag gcgttacaat tcgttcatga taagagtatc
     4861 ttgcatctgg atatcaagcc tagcaatatc ttgatcgata agaacgggaa cgcccgcttg
     4921 atcgatttcg gagtcagcaa acgttacgat atcgagcagg aagagaccag cactacgatg
     4981 ttaacccttt ctaaaggatt cgcatccata gagcaatatg ataacgaagg aacacaagtg
     5041 ttctcgcccc gtccggatat ttattccttg ggagccacga tgtataatct gttaacggga
     5101 acaatcccta cagaatctat actacgtgcc gcacgtcctt tgcgaaaccc ctctgaaatc
     5161 aatgcggcga tcagcccgaa aacagaggct gttatcataa aagcgatgca aatcattcct
     5221 gcggatcgct ttgagacggt gggcgagatg ttggcgtctt tggatttttc tcaagcggaa
     5281 aaggaagttc aggttgtccc aagtccatct cccgagattg tgaatgagga aacaacggtg
     5341 gtttattcat cacctgtaga ttctaaatta gtaggatcgg atgatgaaga gactgttgtc
     5401 aatgtggcta atccacctgc cgtggagcca ataacagaaa agaataattc cagaaagaaa
     5461 ataattccta tcggaatcgc tatatttgtc gttgtaggat ccgctacggc tcttttagtg
     5521 catagcaata ggcccacaaa agaggttgtc gagagtattg atttaccttc agctgtggag
     5581 ccggatagca atgtctcaaa agaagtagaa atgccagatc acccagttct acatacggaa
     5641 cctcctatct ctgagataaa gaaagcggag aaacaagagc ctaaagtgga agagaaacga
     5701 cctatggaaa cagagcatac gatagaagag aatgttctcc cggatcagcc atcggaaaat
     5761 gagatgaatg agaaatataa ctcgttaatc gcctccggta aggaaaaaat ggccaaagct
     5821 gattattcgg gagctaagaa agatttgtcg gaggcaaagg atacgaaact tacggaagag
     5881 gtagtccggt tgatcatcgc ttgcgatgag aaaaccgagg agaaacgtat agcggacaaa
     5941 aaggccctgt atgaggagaa aatggctttc ggacgatata agatcgtacg caagaagtca
     6001 aataacagat acggggcgat cgattcgaaa gccgaggaac gtattccttg caaataccta
     6061 agtgtcggta tcgcggataa cggccgggca ttcgaacggg aagacaattt gtttgatatt
     6121 tataattctg acggatcatt gattagcgaa ggccttactt attattgatt gtaatattat
     6181 gaacaactaa acatgtattt acctattata tgaaaagact ttggatattg atgatatgtg
     6241 cggtatttcc cctcggactg ctggcgcaac agcgtacgga atacaaccgt aagggagatg
     6301 aagcgatgaa acgtcttgat tatagtgacg ctaaaatgtg gtacgaggaa ggcgtatcgc
     6361 aatgcgacgc atacagtatt gatcagctga ctacgatttg gctttccaac gagcgaatgc
     6421 ggccttccat gcgtagcttg atgaataaat gtttaaactg cctgacggtc aaagctacgg
     6481 aagatgatcc ggatgccatc tctaaattaa tcatttatta ttcggaaggt atcggaaccc
     6541 ctaaaagtga ggagctagca acctattgga aagaatacca agagatattg ttaaagccgg
     6601 cggaaccggc ggcccaacca atagattccg cggcggtatc ccctaagaaa cgaatggagt
     6661 ttttcgcggg atactcgtat tcgatcgaat ctccttatgg aatcacggta ggaggtatgg
     6721 ggcaacgctt cggttggtat gtccgtttca agacgaatat gtcttttatg aattatacgg
     6781 acgaatgtaa taaccaaggg cagattatta agttctctaa ttcggaaggg gaatcttatg
     6841 agcttaatac aggtaaatcc tcgaagacaa atagtatagc cggaacggcc ggtttaatcg
     6901 taaaatgctt tccgtggtta tatgcctccg ttggtttggg atatggtgaa agagctttac
     6961 tacattcgtt cacgacccat tcctatgaaa actacgacag tacacgagag gtatggtgcc
     7021 ggaatattga ttcctcatac aaaggggttg ctgccgaggt tgacttgatg atgaaaataa
     7081 cgaactctgt atttattagc gttggatgca acacggttaa ttttaagtac ttggatctaa
     7141 acgctggctt aggtgtattc ttttaatatt gattatttat gaaacatata tactcactct
     7201 tctctattct atttgcggct ttattaatgg ccggatgcgt gaatgatccg gatatagatg
     7261 gtggcattcg aaacgctaaa aaaccgtctg ttaagacaga cgagatattg aagtccacgg
     7321 ctagttccgt gacagtatcg ggggaggtcc tgcaagaaaa cggcgctccc gtgacagagg
     7381 ccggtttttg ttggagcacg gaatctacct ttactgtgat agagaaaaat aaaaaagccg
     7441 tatccaagcg taaggtaaaa tatgaggcta cgatcgaggg cttaaccaat gatctggatt
     7501 actatatccg ggcctatgcg atcaatgcgg tagataccgc ttatggagag attttacctt
     7561 ttaagacgaa agatggatta ggaagcgtta agaccttatt tccagtcaac gtgatgtcta
     7621 cttccgttca atgcggaggt atgataacca aacaaggaga agccgaaatc gaggaaaggg
     7681 gtatttactt aatgctgaat ccggagcctt cagcatctga ctccacgatt cgtatagaca
     7741 tggaagccga ttcgttctat tgtacgatct ccgatttaaa accggaaact acctattacg
     7801 ttagagctta cgcaaaaagt aaatatggtg agtataacgg ggcgaaagtc gagaccttta
     7861 agactacgaa tggtcgtcct gtattagatg ataacaaatt caagaaaata gcgacagagt
     7921 ttacctatgc ggagttctcc atggaaataa taagcgaggg agattctccg atcacggcat
     7981 gtggtttctg ctttagtact gataaatcac cgacaataga aaatggggat acgattattt
     8041 gcggagcggg tatcggagaa tttgccggga aaatctatga tatgcaacag cagaaagggt
     8101 attacgtacg tgcttatgcg acaaacgctt taggtactac ctatagcgca ggcgaaggta
     8161 tccatacgat tctggaaagt gagttgccta cagtcaatac aaaggaggtg tctactatta
     8221 aaaacggtac cgcatgggta ggaggagagg tcttagccga aggtgcctca ccggttacag
     8281 aggctggtgt atgttgggga actagtccta gtccggcctt tggtaattgt gaaggagcgg
     8341 tagctctttc ttccggtaca caagcgttta cgggtacgat aaaggaattg agaggaggca
     8401 cgagctatta tttaagagct tacgctaaaa ataagaatgg tatcgcttac ggagaggaag
     8461 ttcgcttcca aactccggat atatttggag taggggcaag gtttgaggga gctttccgga
     8521 taccgggatc tacctctttc tgtaccttgg ctaatagcac gggattctta ttaggcggtg
     8581 acacgggtag ggaatacacc gatgagtttt ggggatatat gacctctaag aaagaatggt
     8641 tgcccttaag gtctcagcct gagaaattat cgggccaagc atgtttcagt atcggatttg
     8701 gcctatggac ttttggtggt ttagataaca cgggaaagat atgtgacagt ttatatgtat
     8761 actccacgtc cgataattct tggagcgccg tacaaacaga ccagcaacgg cctaaaggta
     8821 tgtatcgggc ggcatgttgc agaatggaag atcaggcgtt cctcataggt ggacgtagag
     8881 gtaacgaact aatcgatgaa gtctggactt atgaaccgag cgctttcgtt tggagcaaga
     8941 aatctaattt cccgattaaa caatacggcg gaatatccgt tgtaattggt gaccgtatat
     9001 atgccggact ggggattatt aataaagcgg atccttcttt ggaatatacg acacagtttt
     9061 ggtctacaga caagaacgct gtagcttggg aaaaggaggc ttcgttcccc ggaaggatgc
     9121 ttttatgtgc tatcgcttat ggtaattacg tatatggcgt agacggggac ggttatattt
     9181 ggcgctatga tccggactct cagaactgga gccagaaatc ccagttacca gcggctaaca
     9241 ggtctgtaca ttgcatgtat gtcttggata attatatcta tatcggtttg ggcaatgcct
     9301 ctaactcatt aatcagttac gatcctactt gggataatta aagatgaata gaacagcgat
     9361 tttagaacag atacagaaga acgtagaacg gctgtcggct cctgatctac cggaatacaa
     9421 atatatcccg ttgcatcaga agccatcgcc ttcagtcgct acgttgcatg agatcatgcg
     9481 cctattacgt acggttatct tccccggatt ctttggtacg gaacaagagg ctcaattagg
     9541 ctctatccaa tattatacgg gagtctattt ggaaaagatc tatgatctct tgcaagagca
     9601 aatatataat ggactttgtt ttgaggtaga gcgttgttgt gattccaagg accgggcttc
     9661 cgatatctcg atcgctttta ttaaccggat tcctcatatc aaatatttac tgtccaccga
     9721 tgtaaaggcc atcttggatg gtgatccggc agccaagagc gtgagtgaga ttatattctg
     9781 ttatccggcg gtctacgcgc ttttacatca acgggtcgct catgaattat tcgagctagg
     9841 cgtaccggta ctcccgcgta tcattacgga aatggcacac tcgcaaaccg ggatcgacat
     9901 tcatcccggg gcgcagatcg gagaatattt cagtatcgat catggaacgg gtattgtcgt
     9961 gggacaaacc gccattatcg gacaccatgt ccgcctttat caaggtgtga cgttaggagc
    10021 taagagtttt acgctggacg aggaaggact tccgatagat ttaccccgtc atccgatcat
    10081 cgaggattat gtgaccattt attccaacgc atccatatta ggacggatca ctattggccg
    10141 aggatctatt atcgggggta acatctggct cacccatagt gtacctccca attccaagat
    10201 atctcaatca cgtgtcgaag aaaaattcac ggaaatatga tattatttga aagagattcc
    10261 gtatgtttgt gcaaatgaca ttacggtgtt ttccttaaat aatagaatat gaccatgaac
    10321 aaagtaaaga cattagatga tctcaagaaa atgcgtgaat ctcttcgtgc gtctttggat
    10381 ctgcgtgaaa aaagcaatac ccctgatcag ctcgtacaaa ttaaggtttc tatggccact
    10441 tgcggtatag ctgccggagc caaggagata atgagttatt ttatcgaggt tttagaccgg
    10501 cagaaaatcg atgcgttggt aactcaaacc ggatgcatgg gctattgtta tgcggaaccg
    10561 actatcgaaa tcaagcttcc gggtcaggag ccgttggtat tcggttatgt cgataaggca
    10621 aaagtagaag agatcataga caagtatatc cgtaagggta tcttggtaga cggcatcatt
    10681 cctgtaactt acaccaccgt aaaacccgaa taagaaattt aatatcttac ataaatggca
    10741 caatacacga attatatatt ggtgtgcggt ggcacaggtt gccgtgcatc acaaagcgag
    10801 cagatcatcg agaatctgag agccgccgtc gagcaatacg gattagagga tacacaagtg
    10861 atccgtaccg gatgcttcgg tttctgcgag aagggtccgg tggttaagat gatccccgat
    10921 aacacttttt acgtacaagt tcaaccatcg gatacggacg agatcgtacg ggagcatttg
    10981 gtaaaaggcc gtaaagtgga acggttactt tatatgaatc cagagaaccg tgagctggtt
    11041 ccggactcca agcatatcgg attctataag aaacagctac gaatcgccct tcgaaattgt
    11101 ggctttatca acccggagaa tatcgatgag tatatcgctc gtgacggcta tgtagcgtta
    11161 ggaaaagccc ttgtggaaat gactcccgag gaagtaatca aggaaatcat ggatagtggt
    11221 ttacggggtc gtgggggcgg tggtttcccc acaggcttga aatggcagat tacccgtaag
    11281 gtacaagcgc ctcaaaaata cgtggtttgt aatgcggacg agggcgaccc gggcgctttt
    11341 atggatcgct ccatattgga gggcgacccg cattcgattg tggaggctat ggcgattaat
    11401 ggatattgta cgggagctag caaaggtttg gtatatatcc gtgccgaata tccgctagcc
    11461 gttgaacgtt tgaaaatagc catacggcaa gcgaaagaat atggattgct gggcgagaat
    11521 atatttggga ctgatttctc attcgatatc gagatccggt acggtgccgg agcttttgtt
    11581 tgtggagagg agaccgcttt gatccacagt atggaaggtt tgcgaggcga ggctaccgta
    11641 aagccgccgt tccctagtga acacgggtat aaaggttgtc cgaccaatgt aaataacgta
    11701 gagacttatg cgaatatccc ggtgatcttg ttaagaggcg ctaaatggtt cagtagtatc
    11761 ggaacggaga aaagcaaagg aacaaaggtg ttcgccttgg ctggaaaggt aaacaatgtg
    11821 gggctgatcg aggttcctat gggtacgact ttgcgtgagg ttatctttgg aattggggga
    11881 ggtatcaagg atggaaagaa gtttaaggct gtgcaaaccg gtggcccgtc aggaggttgc
    11941 ttgacagaaa agcatctaga tcttcctata gattatgata atttgcttgc cgctggttcc
    12001 atgatgggtt ccggaggtat gatcgtcatg gacgaggatg attgtatggt agccatggct
    12061 aagttctatc tggactttac ggtcgaggaa tcttgcggta aatgcgcacc gtgccgtatc
    12121 ggtaataaac gcttacatga aatattgcag aaaattacga gtggaaacgg aaccgaagag
    12181 gatttgaccc gtctaaggaa tctggcgatg gtgattaagg ataccgcttt atgcggcttg
    12241 ggacagactt ccccgaatcc ggttttatct acgatggata atttctacga tgaatatctg
    12301 gcgcatgttc gggagcatcg ttgtccgtct catcaatgcc gggaacttac tcaatatttc
    12361 atcaatccgg agaaatgtaa aggatgtacg ctctgtgccc gtgtttgtcc ggtgcatgcg
    12421 attacaggtg gacggaagat tcctcatatt atcgatccgc aagcttgtat ccgttgcggt
    12481 acctgtatgg agaagtgtaa gttcggagcg atttatgtcc actaaattta tttataagca
    12541 tggaaacaat tcaattaatc atagataata aagaggtgga agtgccgaga ggaaccacca
    12601 ttttagatgc ggcaaaaagt gtaggtatcc acatcccgac actctgttat atgaaactgg
    12661 aggacttgca ctacgagaat aatccgggag cttgccgtat ttgtgtcgta gagatcgagg
    12721 gacgtagaaa tctagcccca tcctgtaaga tggaatgtac ggaaggcatg gtcgtacgga
    12781 cacatacccc ccgggtgatg aatgcccgta ggacggtgat ggagctgatc ctctcgaatc
    12841 atccggcgga atgtctgaca tgtagcagca acggacattg cgagttacaa aagatcgcac
    12901 atgacttagg aatccgtgag atccggtata agggagagat gtccacattt acgatagacc
    12961 gttccccttc cattgtgcgg aacatgaaca aatgtatcat gtgccgccgc tgtgagacca
    13021 tgtgtaatac gatacagaca gttggcgcct tgactgccgt gaaccgtgga tttaacgcgg
    13081 ccgtatcgac tgcttttgaa cgggatatgg ccggaagtac ctgttcgtat tgtggacaat
    13141 gcgtatccgt ctgccctgtt aatgcgctta gcggacgtaa tacgcaacag ccggtcttgg
    13201 acgctttggc tgatcccact aaaattgtta tcgcccagac agcgccggcg gttcgcacag
    13261 cgttgggacg tgatttcggg tatgagccgg gtacattggt tacaggcaag atggtttcag
    13321 ctttgcgtca attgggtttt gattatgtat tcgatacgga ctttgccgcc gacttgacca
    13381 ttatggaaga gggaacggaa ttattacatc gcctaggtag ttacctgaat ggagacaaag
    13441 aggtgaaaat accgttaatg acgagctgtt gtccgggttg ggttagcttt gtggaacaac
    13501 atttccccga gttacgggat catttatcta cagccaagag cccgcagcaa atgttcggag
    13561 cgatcgccaa gagttatttc gccgagaagt tgggagtgga ccgtaaggat ttggtagtcg
    13621 tatctatcat gccttgtttg gcgaagaagt atgaggctag ccgcccggag tttagtgtgg
    13681 aaggtaatcc cgatgtagat tattcgatat atacccgtga gttagcccgt ttaatccgtt
    13741 atgcgaatat agatttcaat gaactgccgg atggtgagtt cgatcgcccg ttgggtgaat
    13801 ctaccggagc gagcgtgatc ttcggtacta ccggaggtgt tatcgaggcc gcttgccgta
    13861 ctgcttatga attatatacg aagaaaaatc tggataaagt ggatttcgag gagttacgcg
    13921 ggctggaagg tattcgtagc gctacgatcg attttaatgg gacttcggta aagatcggta
    13981 tcgctcatgg tctggggaat gcccgcaaat tgatcgagga ggtgaagaac ggtacctctc
    14041 cttatcatgc gatcgaggtg atggcttgtc cgggaggctg tatcggcggt ggcggacaac
    14101 cgttccaccg aggccgtatg gaggtacttc gccggcgtgc cgccgctctt taccgggaag
    14161 acgctaacaa accgcttcgc aagagccatg agaatccgta tatccagcaa ttatacagcg
    14221 agtacttggg agagccttgc ggaccgaaag cccataaatt actgcatacc cattacatag
    14281 atcgtaagga agtaatcggt atgtatatag aaaccgaaaa aagtaaataa gccatgaatg
    14341 agatacattt gcctaaaaca aaagtagcgg agctacatgc gatatgcgct gaacgcaaca
    14401 acgatcccgg ggagttgatc aatatcttgc acgccgccca aggcttgttc ggatatttac
    14461 caccggaagt ccaacaggtt atcgccgccg aattgaatat cccggtctca agggtatatg
    14521 gcgtagttac tttttactca ttctttacga tgacccccaa agggaaatac cccatctctg
    14581 tttgtctggg aacggcctgt tacgtgcgtg gcgcagaaaa tgttctggaa gaaatgcaac
    14641 gtcaattgga aataaaggta ggagagacta caccggacgg tttgttctcc ttggattgct
    14701 tacgctgtgt cggtgcttgc ggattagctc cggtggtcat gatcggcggg aaggtctatg
    14761 gaagggttac tcccgagaag gtacgggata tactttccga ctactatctg aaagagcaat
    14821 aagatacgaa aacacaagcg gtcacataag gttttacgtg accgcttgta taaaataatg
    14881 cgaataatcg tattttcaga aacgactgat cgaaccgcca cccccggagc ttccacctcc
    14941 ccaagagccg ccaccgccgc ctccgctaaa acctccgaaa ccaccaccgc cacccataat
    15001 aatagggcca cctcctcctc ggtgtatgcg gtcgatggta cgattttttt tctctgtata
    15061 cccgcaactc ttacagcggt atacatcttc ggccagacct tccgagaaac gagtcgcttc
    15121 ccggatcacc tgctgcccca tatacacaaa ggttttcttt ccacaacggg gacatgcctt
    15181 cggacgatac tttaagtatg cgataaacgc cgagaaaccg atcatcccga taatccccac
    15241 cacgaatatc cacataaaat catcatcgga cgaggaagaa gaacggttgc cagtcatgcc
    15301 tgcccgttca tagtcgctgg acattaaata cttggtaacc gccatgactc ctttcaacat
    15361 gccggcgcta taattcccgg cctttagatc gggcatcata taccgctgct ggagccggta
    15421 gcaaatcgca tcggggagga caccctcgat accatatccc gtctcgaaaa cgaccgaacg
    15481 ttgggaaggt tccgtcacca actggatcaa taaaccatta tccttgctct tttgtcccaa
    15541 tccccaatgt ttgaataaat ccgtagcgaa catccgggca tcctgatccc cgatgctatt
    15601 cacggcaacg acagctacct cgataccgag actatcttcc actacattta ataattgatt
    15661 gatacgtgcc gcatcatccg gggtaatgat accatccgga ttactgacat ggttcaaccg
    15721 gttggaaaga cgtacgttcg gaatggtctc gatcgaataa tcctttgccg cgaaaataga
    15781 agaggcaaaa ccaaccagca ataaactgat ccataaaagg cttaccggac acttgcacct
    15841 agatcctata ttctttatct cactcattca gcgaatggct attagaattc taccttagga
    15901 gccttttccg caccggattc agcggcgaaa taagctttcg attggaagcc gaacattccg
    15961 gacaaaatat tgttcgggaa ttggcgaata taggtattat aagactgagc tacctcgtta
    16021 aaacgtttac gctctaccga gatacgattt tcggtccctt ccaattgcgc ttgaagctcc
    16081 ataaagtttt gattcgcttt taagtctgga taacgctcta aaacaagcat caaacgggag
    16141 agggcatttc ctaactctcc ttgtgcagac tggaatttct tcaaggattc ctcagtaagg
    16201 ttagaaggat caatcgtagt cttcgtcgcc tcggcacgag cgttgaccac accttctaaa
    16261 gtctctttct catgcgcggc gtatcctttt accgtattta ccagattcgg gatcaaatcc
    16321 atacggcgtt gatattggtt ctcaacttgg ctccatgcgg ttttcacgcc ttcgtcttga
    16381 gttaccatat tattatacac gcctttcacc caaaagaata atatcgctac gatagcgatg
    16441 ataatccata caactttgtt cttaaacatc tttgccttat aatttattga ttatacataa
    16501 tgagacaaag ctatataaaa aaatcggatt atccacatag cgattggcgg ttgcttataa
    16561 ctgcgattgt tagctgctta taatgggcat tgtaacatcc ttatattgcc cattgttaga
    16621 acctcatact gggcattata ggaaggagct tgccgcgatg ctgcggatgg aagcccaccg
    16681 catagattct atttatcttc ccatagataa aactgatcaa tgaaatccaa ggcttttagg
    16741 gtacatgtaa gtgaattgtt ctatatttgc acttaataaa tctaaataaa tatagttatg
    16801 cgtaaaacaa tttatgctaa aatgacggca ttaccggtag gactctgcgc tttagccttt
    16861 gcggttacct cgtgcggttc ttccgaatac aagaaatttg ccgacaatga aggtaagcaa
    16921 gtggcctcta tcctgcggga aaacgactgt ttggcctgcc actctgaaaa tgcgcctctg
    16981 ccattttacg gtaatttacc gttgatcggt cccgtagtac aggcagacat gaaggaggcc
    17041 gttcactatg tggacttgac tgctatggtg gaagccttgg agaacgggca gcccgtttca
    17101 gaggttgatt tggcgaaggt ggagaatacg gccctaagcg gctctatgcc cccggctaag
    17161 tattcccata tgccgatgca ctggggaacc agccttgacg acaatgagaa agcggtgatc
    17221 atctcatggg cgaagaatgt ccgtaaagat cgtttcacga ccgaaaccgt agcggaagaa
    17281 tttaagaatg agcctcttca gcctctaatg aagagcttgc ctacagatcc ggcgaaggta
    17341 gagttgggtt ttgccctgta tcatgatact cgtttgtctg cggacaatac gatctcttgc
    17401 gctacttgcc acggattgaa cacaggtggt gtagaccgta agcaatattc ggaaggtatt
    17461 aatggacagt tcggtggtgt taacgctccg accgtatata atgcggcgct taatttcgtt
    17521 caattttggg acggacgtgc ggcagaccta aaagagcaag cggctggtcc tccattgaac
    17581 ccagtggaaa tgggttgtac ctcattcgac cagatttgcg aggctttagc gcaagataag
    17641 gatttcacga agaaattcac ggaagtgtat ccggaaggtt attctcaatc cacgatcacg
    17701 gacgctatcg ctgagtttga gaagaccttg cttacgccga gtcgtttcga caaatacttg
    17761 atgggagata aaaacgcgct tacagcggaa gaattagagg gctatcaact attcaaggac
    17821 aataaatgcg ctacttgcca cgttggtgta aatgtcggtg gtcaatctta cgagttcatg
    17881 ggtatcaaga acagctattt cgattaccgg aatacagggt tgacggacgg tgataacgga
    17941 cgctatgccg tgactaagaa agaatccgat cgtcataagt tcaaaacccc gacacttcgt
    18001 aacgtgatgc tgacttatcc gtacatgcac gacggaaccg tagcctccgt ggaggatgcg
    18061 atccgtatca tgcatgagtt ccagatcgga aaggagatca atgatgtaga agttgaaaaa
    18121 atcgttgttt ttctaggaac tttgaacgga gaatataatg gaaaaatgct tcaataattg
    18181 attaaaaaag gtacatgtcc ttccgcttgt tctacatatt acttatattt gccgcagtta
    18241 agtgtggaga aggaatatgg gcacaggagg aaggacttgc ttcgtattac catcatcgtt
    18301 tccacggcag gaaatcatcc agtggaaggg ttcatgataa agaagaatta gtcgccgcgc
    18361 atcgtacgta tccttttggt acttttttaa gagtcacgaa cttggagaat atgaaaagta
    18421 ccattgtatg cgtaacggat cgtggacctc gttatagaaa acgaatcatt gatgtatcag
    18481 cgagcgccgc cgagatattg gattttatcg ataaaggtgt cgctaaggta cggatagaag
    18541 tcgttcccgg ccccttagac ctccgctatc tggacttgat ctatcctaag attccttatc
    18601 tggatataga ttatttacgt ccggatccac cttatagggt gaaattcacg aaataaattt
    18661 aatataatga agcaaatact tatcaccggg ggcgccggct ttatcggttc tcatttatgt
    18721 gcccgtcttt tagaagaagg aaatgaagta atttgtctgg ataactattt tacgggaagt
    18781 aaggagaatg tgattcctct gctgaaaaat ccacatttcg agttgatcag gcatgatgtt
    18841 tctataccgt tccaagccga ggtcgatgag atttataatt tggcatgtcc cgcatctcca
    18901 gtttattatc aaatagatcc gatacagacg atcaagacat ccgtgttagg agcggtcaat
    18961 atgttaggtc tggcaaaacg ggtgaacgct aagatattac aagcatctac cagtgaggtg
    19021 tatggagatc ccatgataca cccgcagccg gaaagctatt ggggaaatgt caacccgata
    19081 gggcctcgct cttgttatga cgagggcaag cgttgcgccg agaccttatt tatggattac
    19141 catcgccaaa acaaggttcg cattaaaatc atccgcatct ttaatacgta tgggcctaat
    19201 atgagtacga acgatggccg tgtcgtctct aatttcatta tacaggcatt acaaaataag
    19261 gacattacga tttatgggga tggaaaccaa actcgtagtt tccaatatgt agacgatttg
    19321 atcgagggga tgattcgcat gatgaatacc tcggatgatt ttaccggccc ggtaaatatc
    19381 ggaaatcagg gagagttctc gatgaacgag ttggccaaga tcgtgatccg tttgacaaac
    19441 tcctcctcta agatcgtata ccgcccgttg ccgggagacg atcccaagca acgtaagccc
    19501 gatattacgt tggccaaaga gaaattagat gggtgggaac ctacggtttg tttggaggaa
    19561 ggattaaaga aaacgatatt atactttaaa tctctctaat aaatttctaa tttggcctaa
    19621 gagtattcta actaaatatt cataagcgat aaaagagtga cttctacctt tgcgtaaaat
    19681 ttaacgcaaa tggacagacg agtcactctt ttactttttt tatctcttct tttctctggg
    19741 gcgaaagcct ctgttgtctc cctctccttg aaagagtccg agcaacgttt ctctgaacac
    19801 aatctggaag tgatagccga acggtataat atcgatatag ccgaggctca ggtggtacag
    19861 gccaaacttt tcgagaatcc cgtggtctct ttggagcaaa atgtttataa ccgattgaac
    19921 ggacgttact ttgatttcgg gaaacaaggg gaaacgatcg tagaggtgga acagttgatc
    19981 tatattgccg gtcagcgaaa caaacgtgtc cgtttggaga aaatcaataa ggaaatggcc
    20041 ctttaccaat tcgaagaggt attgagaacc ctccggagcg agttgaagga gaaattcata
    20101 gcgctttatt tcacccggaa atcccaatct atttacgatc gtgagattga ttcattggct
    20161 catctgttgg tggttctcaa ggagcagaat gagaaaggga atgtttcttt attagagaag
    20221 tcccgtatcg aggccctatt actctcttta cggcaagagc ggaatgatat cgccaaccaa
    20281 gttatctccc ttcaaggaga catgcggctt ttactaggaa tatccggcaa tgataccttc
    20341 gagccgatat tcgatgagtc tgtgttgaac cagatcgata tggactccgt tcctttctct
    20401 gaattgacct ctttattata cgaacgtccg gatcttaagt tggcgcaagc aagcgtcaag
    20461 gcttcggagg cggacgtgag attacaacgt tccctcgctt tcccggaagt gagtgtaaag
    20521 ggtacgtatg ataaggcggg taactttatc aatgattatt gggcgatcgg cttgagcgtc
    20581 tctctcccta tatttaatcg gaatcaaggg aatatcaggg cggcgaaaat atctgtcgct
    20641 caaaaggcac ataaggaaga atacgcccgt cgacaagccg agaatgaatt attcaccagc
    20701 tatgcccggt tggaaaaggc gattcagctc tatcgttcct cgaactatgg gttggagaag
    20761 gatttcgcct tgattatcaa aggcgtgaac tcgaatttcc aaaaacggaa tatcagtctc
    20821 cttgagttta tcgattatta tgagacctac aaaacaacct gcctgcaact ttaccaaact
    20881 caaaaagaag tgttactggc cttggaggag gtaaataccg taacgggtag ccatgtattc
    20941 aactattaaa agcaaatcaa acgatatgaa taagcatcta atcacatgca tccttttagt
    21001 acccttggta tgttcctgcg ggaaacaggc gaccacctcg gtcgataccc gggaaccttt
    21061 actattaaat gacagtttac aggagattat aacactggat acggttcgtg acacaccatt
    21121 aaccaacgag ttgttgctca atggccgtgt cagtttcaat ccggagcgag tggcccatgt
    21181 gtatccgatg tttggtggaa atgtcacctc cgttcatgcg gaagttggcg attacgtagg
    21241 gaaaggagat gtcctagcag tgatccggag cggcgagatc gctgatatcg acaagcagcg
    21301 aaaggaggcc gagcatcaac tggctatcgc taaccgtaac ttggaggcta cccaagatat
    21361 ggcccggagc ggtatggctt ccgaccggga cttcctgcaa gcccagcaag agcaagccga
    21421 tgccgatgcc gagaccaaac gtattcaaga aatgtattcc atttataaca taacagaccc
    21481 atctacctat gtggtgaaag cgccggtctc cggctttatc atcgataaga atataaacag
    21541 ggatatgcag atccgttctg atcaagggga ggagatgttt accatttccg gtctcgacga
    21601 tgtctgggtg atggccgatg tctatgaggg agatatcagc aaggtaaaag agggggcaac
    21661 cgttcgtatc accactttgg cctataagga tatggagttt acgggaacga tcgataaggt
    21721 ctatcatatg ctagaccgag aaagtaagac catgagcgta agagtcaaat taaggaacga
    21781 gaagtatatg cttaaacccg gaatgtttac gaacgtatat gtacagagcg cggtaaaagg
    21841 agaaagtatg ccttgcgtaa acgcccatgc cgttattttc gaggatggca aagaatacgt
    21901 tgtctatgtc tcgaaggagg gatatttgca aatgcgtgag atctcggtgt ataagcaaac
    21961 cgagaagttc tgttacctgc gatccggctt gaaggatggg gatcggatcg tagatcggaa
    22021 cgctctcttg gtgtataacg aattaaagta accggacgat atgcacacat tcatagataa
    22081 tatcataacg ttctccctcc ggaacaaatt ctttatcttc ttctgtacca cgatcgccgt
    22141 aatcgccggt atcaccagct ttatccatac gccgatcgat gcgtttccgg atgtgacgaa
    22201 tacgaaggtg acgattatca cccaatggcc gggcaggagc gccgaggaga tcgagaagtt
    22261 tatcacgatc ccgatcgaga tcgccatgaa cccggtacag aaaaagacgg atatccggag
    22321 cacgaccctt ttcggtcttt ccgtcatcaa cgtgatgttc gaagataagg tggatgattt
    22381 cttcgcccgc cagcaagttt ataatctctt gaacgacgcc gacctgccgg aaggggtcac
    22441 accggaagtg cagcccttat atggtccgac cggcgagatc ttccgctata cattacgtag
    22501 cgataagcgt tccgtccggg aattgaagac cttgcaggat tgggtgatcg agcggaagtt
    22561 gcgggccgta cccggtgtag cggatatcgt cagcttcgga ggagaagtaa agactttcga
    22621 ggttagcgtc aacccgaatc aactgatcag ttacggggta acgaccttgg aactttatga
    22681 cgctatcgca aaaagtaata tcaacgtagg cggcgacgtg atcacgaaaa gctcgcaagc
    22741 ctatgtcgtg cggggtatcg gcttgattaa cgatgtaaaa gagatcgaga acatcgtcgt
    22801 aaaaaatatc aatggcacgc caatccttgt caagcacttg gctaccgtac acgaatccag
    22861 tcttccccgc ctagggcaag tgggccgcat ggaggaagat gatgtcgtac aaggcatcgt
    22921 tgtcatgcga aaaggggaga accccggcga ggtaatcgcc gccttgaagg ataagatcaa
    22981 ggatatccaa caaaacgcct tgccggaaga cgtgcgaatc gtatcgttct acgatcgtga
    23041 gaatctggta gatctggcgg tcaagaccgt aacacataat ctggcggaag gtattctgct
    23101 ggtaactttc atcgtattaa tcttcatggc ggactggcgt acgacggtaa tcgtgtcgat
    23161 cattatcccg ttggcactcc tcttcgcctt tatttgtctc cgggcgatgg ggatgagcgc
    23221 caacctctta tctatgggag cgatcgactt cggtattatt atcgatggcg ccgtcgtgat
    23281 ggtggagggg cttttcgtgg cattggaccg gaaagcccgt gaagtaggca tgcccgcttt
    23341 taatttgatg agtaagatgg gtattatccg tcatacggcg aaggaccgtg cgaaagcggt
    23401 tttcttctct aagctgatta tcatcacagc cttggtcccg atcttctctt tccagaaggt
    23461 ggaaggaaag atgttcagcc cgctcgctta taccttgggg ttcgccttgt tgggagcgtt
    23521 gatctttacg ttgacattgg tacccgtcct ctcttccatg ctattaaaga aagaggtacg
    23581 tgagaaacat aatccgttcc ttgcgtggat caatcggaag tcgatcggta ttttcgactg
    23641 gtgtcacgcc cgtaagaagc ggacgatcac gttcgccacg ctggtagccg ccgtaggtat
    23701 ctggtgcttc accttgttgg gcagcgagtt tctcccgcaa ctgaacgagg gctctattta
    23761 tatccgtgcg accttaccgc aaagtatatc tttggatgaa tccgttacgt tggccaacca
    23821 gatacgccgg aagttggcgg cttatccgga ggttcgtcaa gtcttatcgc aaaccggccg
    23881 accgaacgat ggcacggacg cgacaggttt ctacaacatc gagttccatg tggatatata
    23941 tcccgagaaa gagtgggaaa gcgaacgctc gaaagcgggc ctgatcgaga agatgcaaga
    24001 ggatctggcg atctatccgg gcgtggattt taacttctcg cagcctatct cggacaatgt
    24061 agaggaagcg gccagcggcg tgaaaggttc catcgccgtg aaagtcttcg gtaaggatct
    24121 atacgagtcg gagaaaaagg cggtagaggt tttcaaggtc ttggagaccg tagacggtat
    24181 cgaagatctg ggcgttatcc ggaatatcgg ccagccggag ctacggatcg agttgaacga
    24241 gtctcgttta gcccgctacg gcgtggccaa ggaggacgtg caatccatta tcgagatggc
    24301 gataggaggt aagaacgcct ccctgcttta tgaggacgag cgtaagttca atatcatggt
    24361 ccgctacgaa tccgctttcc gccgtagcga gaatgagata ggcaagatac tggttccggc
    24421 aaaggatggt tccatgattc ctatccgcga gctggcggat atccatacga ttaccggccc
    24481 gttgattatc taccgggata accacgctcg tttctgcgcc gtgaaattct cggtccgggg
    24541 ccgcgacatg ggtagcgccg tggctgaagc ccagcgaaaa gtggagaggc aggtaaagct
    24601 ccccgaaggc tataccttga aatggactgg agatttcgag aaccaacaac gggctaccaa
    24661 acgcttggcc caagtcgtcc ccgtaagtat agcgatcatc ttcgtgatcc tattcgtcct
    24721 tttcggcaac gcccgggatg ccggactggt cttattgaac gtgccttacg ccgccgtcgg
    24781 aggtatcttg gccctattaa tcacgaattt caacttctcg atctccgccg gtatcggctt
    24841 tatcgccctc ttcggtatct gtatacagaa tggcgtgatc atgatatcgg acatcaagaa
    24901 taacctgcgg gagaggcatc ctctggaaga ttcgatcaag atgagcgtga aatcaagggt
    24961 acgttccgta ttaatgaccg cctccatggc cgctatcggc ctgcttccgg ccgccttgag
    25021 ccacggtatc ggatcggaaa gccagcgtcc tttggcgatc gtgatcattg gcggattaat
    25081 aggagctacg ttcttcaccc tctttgtctt tccgttgatg gtggaggctt tttatcgacg
    25141 aatgctttat gataagaacg gtaaattagt gcaacgtagg ttgtaattgc tatatttgta
    25201 gcaagaaagt ccggaactat tagggagagc gactggagtt attatgcgaa aggattatac
    25261 ttactgatct tttcacctct gtgatacgat tagcatcacc ctaagtacgc attattaatg
    25321 atggacattc ttattaatac atacgataca atggcgaaga tattattagt agaagacgag
    25381 ataaacatcg cctcttttat agaaagaggc ttgcgggagt tcgggcatga ggtatatgtc
    25441 gcttacgacg gtgccgccgg ttgggaactg acacagaaga acgatttcca attgctgatt
    25501 ctggatatta taatgccgaa gatgaatggc ctgcaacttt gcaaacagta ccggcaacgg
    25561 ttcggttacc atgcccccgt gatcatgctg accgccttgg gaaccaccga ggatattgtt
    25621 agcgggctgg atgccggggc ggatgattat ctggtaaaac ctttcagctt ccaagaactc
    25681 gaggcccgca taaaggcgtt attacgtcga tcgggaaacg aatccgtcca tatggctctc
    25741 cggtgcgggg atctggtctt agatcctcca agccatcggg ctatacggaa tgggcaggtc
    25801 atcgatttga ccgtaaagga atataggctc ttggaatatt tcatacagaa ccaaggaacg
    25861 gccttgagcc ggatgaactt gctaaagaat gtctgggaca aggatttcga taccaatacg
    25921 aacgtggtcg atgtttacgt gaattatttg cgcacgaaga tagacaagga cttcgaacct
    25981 aagctaatcc ataccgtggt gggtgtgggc tatatgatgg aagcatgaag acaggaaaca
    26041 agatcgctct cttttactcg gccattacca taggcgtgat agccgtcgtg acgcttgtct
    26101 tctatttggt ttccacgagc tatatctctc gcctgtacta ttcttacctg acggaaaaag
    26161 cctatgccac ggcacagaag cattgggaga aggacgagac cgacgacgag agctatgccc
    26221 gtatccaaca gcgttacgag gaaacccttc ccgtcgctac cgagatattg ctgaacgccg
    26281 atagcttgga gacccggcaa gtgctgtccc gttatctgga cgccacgcag gtgagatctc
    26341 tataccaaga ggatatcgtt cacttcaagc acgatacgca aatgggagcg gctttgtatt
    26401 atcccgacaa cgaggggaat ttcatcgtga ttgtcctttc cgggaatcag tatgggatgg
    26461 atatccagca tcggatcggc tggctgttgc tgggattgat attggttagc tcggtattga
    26521 tctattttgt cggcagacta tacgcgaccc ggatggtaga ccggatcgac gctgcttacc
    26581 aaagtgagaa agcgtttatc agcaacgcct cgcatgagtt gaacaatcca ctgacagcca
    26641 ttcaaggcga atgcgagatc agcctgctga aagagcgctc cccggaggaa taccaagcgg
    26701 cattaagacg tatcgccacg gagacgagcc gtatcataca attgatcaaa cacctgctgt
    26761 tcctgtcgca cggggataag gagatccaga aaagcgcgat ggagacgatc ttcctagcgg
    26821 acttcttgat gcagttctcc tcggcccgga tctcgttctc cccggataat ttctcttata
    26881 tgatccgtgc caatccctat ttattgaaga tagcgatcaa gaatatcttg agcaacgcct
    26941 gtaagtattc gaacgataaa ccggtagaga tgcggcttcg aggcagtatc ttgaccatat
    27001 ccgaccgagg tatcggcatt cctcccgagg aattgaaacg aatcttccaa cccttttaca
    27061 gggcgagcaa tacccgggaa tacgccgggc atggtgtcgg gctaagcctc tcgctacgca
    27121 tattgagcac ctatggagcg aaggtgaata ttatttctga tctaggggtt gggacgagcg
    27181 tggagatcga ctttgggtag ccgtcagata ttctttagcc ggacctgtta tttcgacaga
    27241 ctccggcgtt acccctaccg cctcttccga agatataagt ccgcgatcta ccaagcgatc
    27301 cagtattacc ctgtaaaaat cctcataata cggcttcaac cgcaacccgt cgaagcaata
    27361 gcggacctgt ttgggtttgg ggataatact ggccataaaa atgcactcgg caaggtttaa
    27421 ttgggaaggt tccttcgcga aataataacg tgaggcctcg gcggctccat aaatcatggg
    27481 accccattcg gcgatgttca gataaacctc aaacatccgc tctttagagg tcagatgatt
    27541 gctctcgatc agccatacga ttaacatttc ctccagtttg cgggcgatcg tcttattacg
    27601 gctcaagaat acattcttca ccaattgcat gctgagcgta ctgccgccac gggcgaaacg
    27661 tcgttccttg atatcctgta tcaacgattc ccggatagcg cttggaataa aaccgttgtg
    27721 ataaaagaag ccggcatcct cactctgcat gatcgctaaa ggaagataac gggatacggc
    27781 gttgaacggg cggaaagagg gattcgccgg accgatctcg aaagagcgta ccggctcgcc
    27841 ttgctcatag acagtatatt caaatggctc attcatcttc cgcaaatccg tattcccata
    27901 ggcaaggatc tggaagccct tcgctttcaa agtagattcc aagatcaagc tgtctacctg
    27961 tccgaaatcc agatccaatc gaaaatgata ggagagggta ccttctgttc tcaggccttc
    28021 cagattgtag aataagcctt taggcaggga ggagaacagt tgatccgcag ggaaatccct
    28081 tttattcaca gaggccgtga tttgccaact ggtatcttta acgatcttca gataaggatg
    28141 gaaatccaga tgattaaacc ggatatcact gacgctatct aattcgatat agttcttacc
    28201 gatgtttgtc cggaagtgta tagagccttt atccagtaag accgtgtccg gagatatacg
    28261 ctcttggtgg atggtaagcc cgctcacata ggcgcttccg agtaaggatt gtatgtcttc
    28321 ttctatttta ggtcccttaa gctcgaaggc caaggtgtcg aaacgtaccg atgcccccca
    28381 acgatattcc agaaaaggaa gaggaatctt cgtatgctcg tcggcgtaga gacgggcttt
    28441 cacgagtcgc tccttatcag agagagagcc ttcgcaaatc cattcgctac gaactccgtt
    28501 ctccgtgctg tttatatgcg tagagaattg attgttagca agattgagtt cgggtatctc
    28561 tagtattagt tcatctcctt tattactata agaaacacat aaatcatgta ccaaggcatt
    28621 tccgggcaat aaattgaaaa gtagactaag ggagcgttca gccttgcgtg cgtaatcccg
    28681 ttccttatca tctacagctg tttccactgg ctcacctggg tgattcgatg gtttataaag
    28741 gaaatcaaaa ttagctctct ctcccttctt aataaaatga atatgcaaat tatccgcttg
    28801 tacactctct atggaagggg taagtagcaa taatctgcca agctccagtt tcgcttgaag
    28861 cctgtccgca tgtatcaacg tatcagcgtc aaccgggata acggtcaatc cctccatacg
    28921 tacggtactc agccccatca accggatctt atcatagcgt atgtcaagat gatgcctttc
    28981 ggcaagttta ctcaatttat gtcccgcata cgcccctaag atcaagtcga tgccccaaaa
    29041 tgccataaac aagagaaagc caataaaaat aagaactgct ataaaagatc ttttatggga
    29101 ttgattcatg ctcatctata ttgttaccca gcggacaaaa gtactataat taaacgaatg
    29161 gatttctttt tcgataaaca atcaagggct taatttagtt atattaaaaa actaaagtta
    29221 tatggcgtat aagattgcgt tttttggtgc taaaccctac gacatcgctt ctttcgataa
    29281 gatcaatgag cggtatgagt tcgatattcg ttactataaa ggacatttga atatcaataa
    29341 tgtcgtctta acccaagggg tagacgcagt atgtattttc gtgaacgaca cggctgatgc
    29401 cgccgtaata gacgctttgg ttgccaatgg tgtgaaactg ttggcgcttc gttgcgccgg
    29461 ttttaataat gtggatttga atgccgccag ggggaaatta ccggtcgtac gcgtaccggc
    29521 ctactcaccc tatgcggtcg ctgaatatac gttggccttg atgttatcgt taaaccgtaa
    29581 gatacaccgg gcatactggc gtacgagaga tggcaacttc tccttgaatg gcttgatggg
    29641 atttgatatg catggcaaga ccgccggtat tatcggtacc ggaaagatcg ccaagatatt
    29701 gattcatatc ttaaaaggat tggggatgcg tgtattggca aacgacctgt atccggatga
    29761 gaaattcgcc aaggaggaag ggatcaccta tgtctcttta gacgagttat acaaagagtc
    29821 cgatatcatt tccttgcatt gcccgttgac cgaccagacc cgttatctga tcaacgacga
    29881 ttcgatcgcc aagatgaaag acggcgtaat gattatcaat acgggacgcg ggttactgat
    29941 ccataccaac gccttgatcg agggattgaa gaccaagaaa gtatctgccg ctggattgga
    30001 tgtctacgag gaggagggag actatttcta cgaggataaa tcggataaga ttatcgatga
    30061 tgatgtcttg gcccgtctgc tctcgttcaa caatgtgatc gttacttccc atcaggcgtt
    30121 tttcacgaaa gaggctctgc ataatatcgc cgagactacc ttgcggaaca tcaaggattt
    30181 cgaggaaggc cgtcccttag tgaacgaagt gaccaagtaa attctaaaaa ggaactatta
    30241 tttatcgctg atttattata tttttgtggc cattgcttgg tgggaaccca gcaatggctt
    30301 ttttaattca gaggtatata tatggaaata gatagtcaga caggtttggt gttggaaggt
    30361 ggcggaatgc gtgccatatt tacggtggga gtattggatt attttatgga tcatgatatt
    30421 tggtttcctt atacgatcgg agtatcggcg ggcgcgagta acggaatctc gtatgcttcc
    30481 cgccagcggg gacgctctcg ttttagcaat atcgacctat tgaagaaata taattacata
    30541 ggtcttcgtc atttcttacg ggggagggga tatatcgatc tgaatttctt gttttatgtc
    30601 tatccggatt tgtattatcc gttggattac gatacctatt tcaagtccaa ggatcggttc
    30661 gttatggtca cgagcaattg cttgacgggt aaagcggaat atttcgagga gaagaaagat
    30721 aagaaacgtt tggtggatat ctgtaaagca tcttgcacat taccgatcct ctgtccaatt
    30781 acgtatgtag acgggatacc gatggtcgac ggaggcgtat gcgatgccat ccctatccga
    30841 cgggctatcg ccgacggctt ctccaagaac gtcatcatcc ttacccgtaa caaaggctat
    30901 cggaaagaag agaaagattt ttaccttccc ggctttattt ataacaaata cccggcgatc
    30961 cgggaacagt tgcgactacg ataccggcgg tacaacgagg tcttggatta catagaccaa
    31021 ctggaggccg aaggaaaagc cttcgtcatc cgtccgcaaa gcccgattaa agtcggtcgt
    31081 accggaagcg acacaaagaa actggaagaa ctatatgagg aaggctacga atgcggaaaa
    31141 caaatcactc aattgtagag acggggcatg ccccgtctca tcccctcaaa acagtatttt
    31201 atttacaacc ttgcaaatcc ttacttaacc gcatagcgca gaaattagga ccgcacatcg
    31261 tacagtactc tccatccgta acagcactct ccttataata ctgtaaagcc ctttccgggt
    31321 ccaaggacaa attgaactgg tctttccagc ggaaatcaaa acgggccttg ctcaacgcgt
    31381 tatcacgtac ttgagcgccg ggatgccctt tcgccaagtc agcggcatgc gccgctatct
    31441 tataagcgac caccccatta cgcacgtctt ccttattcgg caatcccaaa tgttccttcg
    31501 gcgtaacata gcagatcata gccgtcccat gccaagcgat ttgcgcgcca ccaatagccg
    31561 acgtgatatg atcgtatcca ggagcgatat cggtcgtcaa cgggcccaac gtatagaacg
    31621 gcgctccatg gcaggcatac tgttgttcct tcatattctc atgaatctta ttcatgggaa
    31681 catggcccgg gccttcgata atcacttgta cgaactgctc ccaagctatt ttcgtcagtt
    31741 ctcccatcgt gtgaagctcg gcgaattgtg ccgcgtcgtt cgcgtcatag atagaaccgg
    31801 ggcgaagccc gtctccgata gagaccgcca cgtcatatgc ctttagtatc tcgcagattt
    31861 cggcgaaatg tgtgtacagg aagttttcct cgtcatgaag ctgcatccat ttagccatga
    31921 tagatccgcc tctggagaca atccccgtca ggcgagtcgc cgtcagctcc acatgtttac
    31981 gcaacaaacc cgcatggatc gtgaaataat ccacgccctg ttccgcctgc tcgatcaacg
    32041 tatcccgata gatctcccaa gaaaggtcct ctaccttacc attcaccttc tccaaggctt
    32101 gataaatagg aaccgtaccc atcggaaccg ggcagttacg gataatccac tcgcgcgtct
    32161 catggatatt atcgccggta gagagatcca tcaacgtgtc tccgccccat ttacaactcc
    32221 atatcgcctt ctcgatctcc tcgtcgatac cggaggaaag agcggagtta ccgatattgg
    32281 tattgatctt taccaagaac ttcttaccga taatcatcgg ctcggcttcc gggtgattga
    32341 tattcgccgg gatgatcgcg cgaccggcgg cgatttcctt gcggacgaac tccggcgtga
    32401 tatacgactt cagtcccaaa gcctcgattt gctggttctc acgaatcgcc acgtactcca
    32461 tttccggagt gataat
//
LOCUS       DBMDTB010000034        32305 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_537_length_32305_cov_12.614458, whole genome shotgun sequence.
ACCESSION   DBMDTB010000034 DBMDTB010000000
VERSION     DBMDTB010000034.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 32305)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 32305)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32305
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_537_length_32305_cov_12.614458"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            291..515
                     /locus_tag="ACZPB4_07470"
     CDS             291..515
                     /locus_tag="ACZPB4_07470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010182747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098095.1"
                     /translation="MKSCEMHLVLVLSDHVNVGKDPLYRPPKTQKAEEGRTTQTTVYP
                     HVKASGKFPGKNPRAQKAHLYAFKETFLEK"
     gene            complement(1596..2443)
                     /locus_tag="ACZPB4_07475"
                     /pseudo
     CDS             complement(1596..2443)
                     /locus_tag="ACZPB4_07475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863959.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
     gene            2628..3062
                     /locus_tag="ACZPB4_07480"
     CDS             2628..3062
                     /locus_tag="ACZPB4_07480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HIR1098096.1"
                     /translation="MAVKFKVVKRKVLNGAEKDSVKNYAIAKTSGTSDLNKLCKLICS
                     RSTLSSADVKAVLDSLNWAMDLELSSGNVVQLGEFGNFRMSINSEGTNTPEDFDATKI
                     KGVRIIFFPGSALRTTRNEVNFEPLEVTKKSAGSDSESPDEI"
     gene            3059..3529
                     /locus_tag="ACZPB4_07485"
     CDS             3059..3529
                     /locus_tag="ACZPB4_07485"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010182744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_process: GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HIR1098097.1"
                     /translation="MRKIDLIVIHCSATRENTDYSPEQLESDHKARGFLRAGYNFYIR
                     KSGEVVNLRPLEQIPAHARGHNKHSIGICYEGGLDITGQSRDTRTQAQKTSLLRLIRH
                     LLICFPGSWVCGHRDLSEDLNGDGTISPDEWIKQCPSFNAISEYKELVYELRKK"
     gene            3600..4574
                     /locus_tag="ACZPB4_07490"
     CDS             3600..4574
                     /locus_tag="ACZPB4_07490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecR family protein"
                     /protein_id="HIR1098098.1"
                     /translation="MENSIDHIITRILSGNSSSEDFLSLSEWLNADEKNKKEFRLLKS
                     YWDAEVSFSHSLMPNVSLDNLRKKIDDQSRQKRLRLIRFIATPIAAAIAFLVLFFATI
                     HLNTREAKVQQFYTYITDKNKSHFTLDDGTKIILNRNSRFTYSDAYGTDQRKVNLEGE
                     AYFEVAKNPERPFIVDMGNASIRVLGTTFSVKADKGKDQITAVLLEGSIRFESPTQQV
                     LLAPDQQLTFIRSTNKIDIQSVNAKENLAWKDGLLKYKSIALCTLLNELEKRYEIPIH
                     IENKRLLDPNVTVSGTFSEDQSLKEILQVISRSLPIKWSQRDGTYYIQ"
     gene            4818..7979
                     /locus_tag="ACZPB4_07495"
     CDS             4818..7979
                     /locus_tag="ACZPB4_07495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SusC/RagA family TonB-linked outer membrane
                     protein"
                     /protein_id="HIR1098099.1"
                     /translation="MLSVLKMSFILLFLTLFQAVATNSYSQSVTISVKTDQAPLTDLF
                     AIIEKQSDFLFFYVDSDVKNVKVSVNATDKSIENILSQALRNTSLKYSIEGRNINVFN
                     KNIVAQQTKKRITGVVKDPEGNAIIGANVVEKGTTNGTITDLDGKYVMEVSSNATLEF
                     SYIGYMTQLQPVGGKNEINVNLKEDTQKLDEVVVVGYGTQTKREITGSITNVTAEDFN
                     QGLTRNAADLLQGKVAGLTINTGSGDVTGNSTIQLRGLSTLQNDQGPLIVIDNVPGMD
                     MSTVNPQDIESISILKDASSAAIYGSRSAGGVILITTKKGYASKPTIAYNGAFGVSTL
                     ANKPNLLTADQWRSYTSSTPGKDGKDFDMGANTDWFDEITRIGFQQDHAVSLSGGGSH
                     HNYRGSLSYMQREGIARDNSMNRYNARFQFSQRALEDRLKVSITGVATVTDNAPTNAT
                     NFLLAYNMIPVRPVKLEDGSWFDTREYDQGNPVRNQKENTHKNRINNFYGTADVGYTI
                     IDGLEAKVLLAKSRNTEDESKYNSIESQAGYNDGGKAERWSRLRDKDLMEWTANYSAE
                     FNKHKINALIGYSWEEENYEETHVQTRGFVTDLLGANNLAAGQNLNPGDAESQKWQSR
                     LISLYARANYSFNEKYMLTATVRRDGSSKFGTNNKWGTFPSVSVGWNVTQESFMEKVN
                     WLNDLKLSVGYGITGNQTGLDPYKTLELYGTDGVYYDTGSWLPSYKISQNANPDLKWE
                     QTAMLNIGLDFSVLDSRLGGRIEWYNKKTSDMLYTYPVPTPPYLYSEIMANVGDMRNT
                     GIELSLNADAIRTKDFDWNISLNLAHNENEVTRLSNDVFTMDKILLGDVFIRGGSSSG
                     THVLEEGRPIGQFYGLVCNGIDENGRYIMVDKDGDGEISDPADYDYIGSAQPKLTYGI
                     TNTFRYKNFDLSFFLRGTIGNDILNATRMAYAQSGFLPGTNALDDPLTYTLSETPRFS
                     NYYLEKGSFMRLDNLTLGYKIKALNGIRVYFTAQNLFVITKYKGLDPEVPMDSGDGLT
                     PGVEPREFYPKARTFSVGLNLNF"
     gene            7999..9567
                     /locus_tag="ACZPB4_07500"
     CDS             7999..9567
                     /locus_tag="ACZPB4_07500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RagB/SusD family nutrient uptake outer membrane
                     protein"
                     /protein_id="HIR1098100.1"
                     /translation="MKRLFKNIICAVLAPVALVSCMDLDENVYDKLPTDEFGTTEKQI
                     NAIMAPAYQSLKNMLAYDGPWGAADMTADILIAPTRVGGDWWDGGQYMEQCMHSWKPN
                     SYSVENCWTYCTEGLTTVNSVYNIIEKSEAMSDELKLQYLSELRGLRAFWYYVIVDIF
                     GNAPLVTDFEDTSLPSITSRADLYKYVVKELTEIIPNLRSDVSDASYGKFTQGAARMV
                     LAKMYLNAEEWIGEPNWKGVVEQCDEIMKLEYIIEPNWKTNFEVHNEVSREIIFPICY
                     KASDAWGNSIHLWTLHYLDPDVLGFTGGMWNGINAQPDFVRTFDTEDPRYEGSFLIGP
                     MIDPSTGEILKTTLGHDLIHTIDLNVVPGTEKTDADGNLTPWGEVHQEDGARINKWVY
                     EKGMQNTNMENDIAIFRLADVYLMKAEALVRMGGDLGEATRLVNAIRERAYGNSDHNY
                     TSVTLDDIYNERGYELAFEFVRRQDMIRFGTYLKPRYMKPKQTPEYRKIFPIPFKAWQ
                     KNNNLVQNPGYPAF"
     gene            9640..11184
                     /locus_tag="ACZPB4_07505"
     CDS             9640..11184
                     /locus_tag="ACZPB4_07505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family protein"
                     /protein_id="HIR1098101.1"
                     /translation="MKEVNKQSCPTGISRREFLGMAATGAAALTILPSFTVAGLGHVA
                     PSDKLYIAKIGCGGMGAADLGSLMNTPHKNAAITCLCDVDDRQSADARKKYPKAKYFN
                     DFREMYDKEGKNFDAVCISTPDHNHAIQAFGAMRMGKHVYLQKPIAHDIYEARILTEA
                     AKKYKVVTQMGDQGNSCDGMRTLREWFEADLLGDIQKVYCWTNRPVWPQGIPWPSQKP
                     EVPKGLNWDLWVGTAEYVDYIDNLVPFNWRGWWRFGTGALGDMGCHIIGPPFKLLQLG
                     YPTEVSCSTTNVYSGIFEEAYYPESCPVASSIRYKFKKKDGSDLNLYWMDGGIMPERF
                     EEIDPDADMTCTMGDLDMMDVEGATVFVGTKGMASCGWGGSDPRFWPKGQKANKKPLF
                     DKDVNIPHKYKRIEGGTNGHYWAWIDSCIAGYDKADVESPFEGYAGPLTETVLMGNLI
                     LRSYNIREQVKHNDSIYGEREGFIYPGRNKTFQWDGANMRITNFEQANQFIKRKYRDG
                     WEEVKL"
     gene            11368..12174
                     /locus_tag="ACZPB4_07510"
     CDS             11368..12174
                     /locus_tag="ACZPB4_07510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-disaccharide hydrolase"
                     /protein_id="HIR1098102.1"
                     /translation="MKKIYSSIMVAALFASAVSCTSGNSSSAGSTQTAKGQACPNDGI
                     PEGGEWITMFDGKTLNGWRGYCRQDVPQGWVVEDGSITYKGSDNKADTGFGDLIYDKK
                     FKNFVFEIEWKIDKAGNSGIFYTAQEIEGTPIYYSSPEYQLLDNENMPDAWEGCDGNR
                     QAGAVYDMIMPDPQPVKPYGNWNKTRIVVYNQRVIHYMNDVKILEFQFGTPVWRALVD
                     HSKFSKFSTSPEKCPEAYDLMLQCGKQPGYIGMQDHGYGVCFRNIRIKEL"
     gene            12181..12903
                     /locus_tag="ACZPB4_07515"
     CDS             12181..12903
                     /locus_tag="ACZPB4_07515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactosamine-6-phosphate isomerase"
                     /protein_id="HIR1098103.1"
                     /translation="MRIEICQSYEALSLKAKEIVTSELGQHKALTLCAATGGSPTRMY
                     ELLVEEAGRQPELFSQFTVLKLDEWGGIPMDHPGTCESYLRNYFVGPLQIPEDRYIAF
                     QSDPENPEAECERIQQILDQKGPIDICILGIGMNGHIALNEPAPSLHTNCHVAHLSQK
                     SLQHPMIAGDTEKPGYGLTLGMANIFQSRLIILLINGIKKREITQAFLEQKISTELPA
                     SLLWLHPNVICLIDREAAHSSN"
     gene            12919..13845
                     /locus_tag="ACZPB4_07520"
     CDS             12919..13845
                     /locus_tag="ACZPB4_07520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HIR1098104.1"
                     /translation="MKYAIALDIGGTSIKYTLVNQNGDILYESSETTQSKENPRPLSD
                     IIKSIVRKMTDYARSRDWGIYGIGIGVPSVVDKGVVLFANNLPELDNQQLDLALAEFN
                     LPVFIDNDANLMGLGEVIYGAAKGLSDIVFLTMGTGIGGALFLNGRLYGGYRNRGTEL
                     GHLIIHGLNGNQCTCGASGCLEAHASVSALIALYRQLLEKNGREIPSRIDGKYIVERY
                     KAQEKEAVLAMEDHFRNLSLGVASLINIFAPQKVIIGGGISESGDFYINNIREQVWKF
                     VMKETSYFTTIELARLGNKAGCLGAAALVFNH"
     gene            13857..15128
                     /locus_tag="ACZPB4_07525"
     CDS             13857..15128
                     /locus_tag="ACZPB4_07525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HIR1098105.1"
                     /translation="MNKNNWIVLLILCIWFVISFVTNILGPMLPMIIDSFGLSLTLAA
                     FLPFSFFLAYGIMSIPAGMIIERFGGKISLLVAFSLAFLGAGLFVMFPTYPIVLTSLF
                     AIGLGMAMLQVIILPLMREAGGEKKYAFNQVLAQIVFGAASFMSPFVLAGLMRKLTGE
                     DSANDFFIRFLKGITPESLPWSSLYFIFTIVFVIMLVVISYVKFPKVELKEDEKAGTV
                     QNYKELLRQKQVIFYFLGIIAYVGTEQGLANWMSLFLNMYHGVSPEGAGATTVAWFWG
                     LMSIGCLLGLVIVKLIDSKLMLRIFSMIAILNLSIALFGPTQVAIIAFACCGFSISIM
                     FSVIFALALNSVDKHHGAFSGILCTGIFGGALIPFIIGGLGDLIGLRYSMFFLFITLG
                     YILSISYWAKPLVKNETVSLKELLKQLNRTK"
     gene            15163..17244
                     /locus_tag="ACZPB4_07530"
     CDS             15163..17244
                     /locus_tag="ACZPB4_07530"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 97 protein"
                     /protein_id="HIR1098106.1"
                     /translation="MKKESIYLILAFFILCAHSLYANKSVRLSSPNGKIKFSLVLDKN
                     SPVYSVAFNKQTLIQDSPLTLTFDNGAFGENVKINKPVFSTKEETYELIVGKAKHIHS
                     LSKEVIIPLEETVQPFRKINLVLRAFDDGIAFRYEFPKQKGWDSYIMYDEGTTFNLQG
                     NPNVTTLFLPNYQSSHEGKYTVTDYADMDNKRLMDMPALFSFPNHVYMAITEAAVRDY
                     AGMYLWKENGTLLGKLSPKLGQERIKVEASLPHQSPWRVLMISDQIGSLIASNILTNL
                     NEPCKIEDTSWIKPGKTTFTWWNGNVVPDTTFLGGNNFPTNKYYIDFVARNGLDYHSI
                     YGNAEQAWYDEDGAGFGSPGPKADILKVVPSLNMQEICDYAKSQGVRIHLWTNWKPLY
                     AKIDEAFAQFEKWGIAGMMIDFMDRDDQEMIRIQEEFLAKAAKHHLFVQFHGACKPSG
                     LSRTYPNEFTREGTLNYEHCKWDKDTDADHDIHMPFTRLLAGATDYHLGGFRSLPRDK
                     FKNQERNPYVMSTRCHMLAMYVVLESYLGMICDTPEAYEGQPGFEFLKAVPTTWDQTV
                     VPNASVNEYVTIARKKGEDWFVGTINNSQARSIDVDLKFLDKDKKYKITIYKDAEDTN
                     IDPNKLVKEVEEITYRDKITLPLASDGGSVFHIQPSDVTHPLQPGLRWYCKADAVILQ
                     RPYSNAATPVQ"
     gene            17325..18041
                     /locus_tag="ACZPB4_07535"
     CDS             17325..18041
                     /locus_tag="ACZPB4_07535"
                     /EC_number="6.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008641 - ubiquitin-like modifier
                     activating enzyme activity [Evidence IEA];
                     GO_function: GO:0061503 - tRNA threonylcarbamoyladenosine
                     dehydratase [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA threonylcarbamoyladenosine dehydratase"
                     /protein_id="HIR1098107.1"
                     /translation="MSYNWNTRTELLFGAEHMECLSRSHVLVVGLGGVGAYAAEQICR
                     AGVGKMTIIDADTVNESNINRQLPALHSTLGMPKAEVVAKRLLDINPQLQLTVLNEFL
                     RDERTEEVLLSAPLDFVVDAIDSLSPKVYLMYQAYIHKIPIVSSMGAGAKVDPSLVRI
                     ADISKTINCALAKAVRKRLRPLGVSKGIPVVFSTEFADPDAVIEVENETCKRTTTGTV
                     SYMPATFGCFLASHVLRNLI"
     gene            18038..18694
                     /locus_tag="ACZPB4_07540"
     CDS             18038..18694
                     /locus_tag="ACZPB4_07540"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1098108.1"
                     /translation="MIQTEGITKSFGALQVLKGIDLTINKGEVVAIVGPSGAGKTTLL
                     QIIGTLDAPDSGRLVINGTETRRLGDKELAAFRNRNIGFVFQFHQLLPEFTALENVMI
                     PALIAKEKSAIAEKRAKEMLDFLKLSDRMAHKPAELSGGEKQRVAVARALINNPAVIL
                     ADEPSGSLDTKNKEELHALFFELRDQMNQTFVIVTHDEQLATNTDRVIHIKDGVVETN
                     "
     gene            complement(18711..24635)
                     /locus_tag="ACZPB4_07545"
     CDS             complement(18711..24635)
                     /locus_tag="ACZPB4_07545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098109.1"
                     /translation="MKPSINLRYKSLLLTCLLIFSAGVAVPAWGQTYTINYKNGSPQT
                     GITERVDTVYVADGEERELFIPELRNNDGFYNANYRWYVRWYQLNEGNLSCENIKGKA
                     INPKLDGSFVQGGALQDLINLYPSSLRDAGTSLFFYKDFYKIEGTTAINSSVPLGAST
                     VEYSAVNVKEDLVVCDVSLNNNYKVDGTTFTEPTLSIRYKFVIRPASEIANRIKDSKA
                     DETTPFMDETIYVPQNNGTINIQLGRIANNYAWYDGDQIVQGETYQYKKDNGEWKDLG
                     NRWTQIINNLITVGTQPVKLEIRAVGKDKTKASPLLVRYNLISGDHGFMLQEKQEKDS
                     DPRRNPDNYPEFYERIGYINFDRNDSISVDDLNSVNNMAKIGFSDNKEDKGKWLDPEI
                     TGYAPFNYQIQPNKDNRIQTLQNQYGLFRTADVEKVSTNNEKVEGKTYFWFASAQSKP
                     KVAIYDRTYYNTGKKSLGYFFYVDAANLPGRLVKIPLDGNICAHTGILVNFWVNDMTT
                     WKDTQAEGKPLPPNVNMNFIGLKADGTEVVLHRFTSGDALTDYTSTSEGRPANNNIGK
                     WQQLMYSFSLSQSLDDYVGYYLEVQNNTAHSYGADYAIDGLRIYRSIPQIDVKRVDVC
                     SSASLTVATDYELLLKNMGWSINPDVLSDLNMGNSITEDSKHIWRYRYGLMGGDPRKR
                     NENLNKTIGNVYIGATDKKENGDIKKPEDWITLNTDLKDYSNERYNNRSKVYRIIVPT
                     KEGLKHQGFEDLTNHETAMRRQIVVNLRMINDFLYDAAEHKIWQKDILDHAQKTNGDK
                     FPEEEYIAYLKQNLSVLCGKSDSEWDYKIPEPKDLSNQIDRIMEGNDNNLYEELIRAV
                     CSVMGISRPRMPWWDEGNSNTIHLSAIDVDKTELKYKGEQNFGSKENAASGRYDVVIF
                     SAATTVTSDEIVDFPNAHAGDSFNDPCLLTTPFTVLPSFTVVAKTKTDLPEGMIACEG
                     RISQIEEATMWVERYDKDNNLMTGETDKFVDRYKGYSYTFDWFLGDSLEFAAFYDEYG
                     FSLEEILKSYRNTLPDAEKALSFPAKNLIEYYEKLDAYKDKPALIAKLKTLLLGDVDT
                     EPKLVIGGNLGYAEFRWVKKVVAIPYLPESIPEKDRLWLFCDRPQERSLKAAPAPKLL
                     VGFPDVKYPEGMEHYPNVPLRIGLPNIMEKSITNIPIQSNGLKMGMTESNQLGLPESN
                     TTDIFLRQGATYTKVGNLTKLSAKAKSKNEAGETDYGGGLFSMTFDDKAYTNFDEGQI
                     YALYIPFGEYKDEAFVKGSCEGYATLLIKIVPEYLTWKGTNTGEDAEAWYNDANWHQS
                     TKGELYIDPNGEDKTDANGNDADLTAAFAPLHFTRITIPEKQMLELEGLETKDHLLQI
                     PEANSSKATEYIQYDMAVDKDGDNTIVTPYYINKVKAIYFKPEAQLRRQQFLTYDTAH
                     VEFEMTPDAKYWMASPLQSVFAGDMYTVKNTGRQNTYAFADITYSTADNDRQAPAFYQ
                     KAWDKAITMYVPKSEADQIVSFPENGLDTTHYEVVQSNWSREYNDVNVPYALGKGFYA
                     SVEKKNATGLGEKVLVRLPKADDSYKYEPWKPDTKSATLRAAMTKAPTLANRINAGKL
                     ADNKSIKVVLTDVNGTEDWWNTDNGTVRVIADGDGKHFLLGNPYMYPLDIVRFLKENE
                     AILEQKYWTLDVKEGLVVGTPDVAWEGGNVTDATSGAVIASMQAFFVELKDAAQTKAE
                     GTATGTDLKVVHFDPSMMQGESEKVSSSLRTATAKNPVLRLTAERDAYRSTALLTRQD
                     DAANSYEADKDAVILLDTELEEIPQVYTIAGTRAVGVNVVRRIDQVPLGVYAGEGKGE
                     VTLTIEGIGDWAETLYLYDAVTRKSTELSDNTYTLRLDGSSHGRYFLSAGSPTGNEGV
                     DNVESISVYSAVSGRIVASASEALKRIQVFTPMGRLVRTLYPARPTYTFDLPAGIYII
                     RTEIAHDQKTVKLRVL"
     gene            complement(24682..26382)
                     /locus_tag="ACZPB4_07550"
     CDS             complement(24682..26382)
                     /locus_tag="ACZPB4_07550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010182732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FimB/Mfa2 family fimbrial subunit"
                     /protein_id="HIR1098110.1"
                     /translation="MMRRYTIYNRLTAVAAGLCLCWLFMACGEDRGGDLPDDDPNHCV
                     VTITLRTSRSVRPPQTKAEGMMTKAEGMMTKAEGMMTKAEGMMTKADETTETDFWAKD
                     EEYERDITNWLVVAYDENADFAGYISGKDGTWTPDISNEDSRTTVEMKLPFGTYHFYA
                     FANLQSLEDGTSLYQKITEAHSLAELSEVKILDSGTSIDTRNEEKKGKFGGEEASRKR
                     IPMSSYAQKHTVLPAPAENKFEIPLIRMIGKVQVEITNNLDKSITVNQLDIMNLRKGS
                     LPIWLLPWGNENYLEFKDNKDLEEPLAPSFPKDANPPVVSLEDLYTESIKPGDNEKEI
                     QAKHVDGENGSKRAYIRYIPETNAAVGENGGGIHLGVEIEGRPRTEHLTGFDFVRRND
                     LLVIPVLITNITTKLEVAEQRLPIGVYPTALFYGEKTGVQILTPVEHTLQAAGDLSIR
                     FEISSIEGVTGDFTIKGLPQEGTVTETAKISSIQVKSDEKRLITAVNGEDCDKKQRFY
                     LPEASIKEGKKGSFTIRTRELGGNVDATVILTLIINYYVGQEKQEMQIPYTIKIRNYK
                     "
     gene            complement(26407..27534)
                     /locus_tag="ACZPB4_07555"
     CDS             complement(26407..27534)
                     /locus_tag="ACZPB4_07555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009016479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FimB/Mfa2 family fimbrial subunit"
                     /protein_id="HIR1098111.1"
                     /translation="MNRLFHTCKQLIGIAALSVGLYACDWIHDDSLPLCEFRLYFKYD
                     YNMKFADAFQHEVDFVTLFFCDQEGNFLFQRRIEKSELDERNSIALDMEPGTYQVVTW
                     AGLDKGSYAWNDPAETSQAVGRAQDVKVRTLREANTTQPNELHPLWHSLDTFTVTRDM
                     PEADTISLAKNTNKLRVVLQNVMGEDMDVNNFSFRIVADNGYMDYDNSLLQDPTIHYL
                     PYYTENVELGADPTPGATVGGQYVAVAEMNTMRLMAGRNYRLIIRHHGWEKDVLNVNL
                     NDYLLLTKMEGHRISPQEYLDRQDEYSIIFFLTPKVCPDCPDKPTPPDPPDPSGPDNP
                     DNPDNPDNPDGPDPEDPTIVGYACFKIQVKDWVIRINDGIL"
     gene            complement(27701..29788)
                     /locus_tag="ACZPB4_07560"
     CDS             complement(27701..29788)
                     /locus_tag="ACZPB4_07560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967052.1"
                     /note="Members of this family are fimbrial shaft proteins
                     (major subunit proteins), found in the Bacteriodetes. The
                     family is named for Mfa1 from Porphyromonas gingivalis,
                     and is related to but distinct from the family of FimA
                     from the species; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0009418 - pilus shaft [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Mfa1 family fimbria major subunit"
                     /protein_id="HIR1098112.1"
                     /translation="MKKKKWYVAMATALLLAAGCSDDLDNGKNNTGAEEDGEKVYMTV
                     NVSTVSQGTLTKADTTPSNPNQGGAGWGEDGNGSLGELSGSKEGMVYDVNIFLVPTDE
                     ESLGDGNQLELLNTDNGSSIQIAGQGYYSNLEGIDASLGGTEPGHGDGKVTMKVTMKN
                     PLTQDKSNYQVFAVINAGGRLTGISTLADLRDRVAANDRALWTPASNMAEYHHFVMST
                     HKMISGAIPSNGSSIVELSAANMDETYPARTTVFVERLAARIDLAYSSNLDLTNIPGT
                     SPVKNKGTFTLKRYKVVNQWKGESYLFKQVSPTVQYNYGANAVLPADGTNDPVRYLGD
                     EKWIWRNNDTGAGSYNYVLDPKIREKKLPEGESSSWDQFKDSYVNYFNPSNSTDLNNL
                     DKMVSMPTSGLSYTQEVSGDSRTYYPVVYTKENTLDLNSQVHGYTTGVIFESEFTPSN
                     DFKVSSYENGEIKSVNLPNGDKTFLSAAHYNSNGSVSRLVYKDVKSVAARAFNLENDK
                     KNLLKGFMDGWDDITADVNAVKKAVQDMSSQNGLESAFKEYLDGILTGKATLDEDLKQ
                     KLTYAAFRRQASHLPSNITPVSQFCSEQIGNLYQYYNVSLYKSGRSYHKFWIRHNDNG
                     NDGLMGVMEFCIVRNNVYQLYVKGIRGLGDPLPYTPGKDDPGTPDESDDVTIDVTIYV
                     KDWVKRTNKDIIL"
     gene            complement(29825..31285)
                     /locus_tag="ACZPB4_07565"
     CDS             complement(29825..31285)
                     /locus_tag="ACZPB4_07565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010182728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3868 domain-containing protein"
                     /protein_id="HIR1098113.1"
                     /translation="MKNLQGWMILGIACLAGCVGTTIPVQAQQTATAIVVKERLVEHV
                     GDRLIIDMKLALDELSLSANRSLVCTPLIERGDSVRALPPVIVNGRNRQIQYERSKRD
                     ATANGEFVLRRHNGKEQTFDYHASIPFVKWMERSEVSLVADFCGCGWEALSNDKSPLF
                     PIRIAEPVVLRPLLAYVTPEAERVKERVKEGSAFLDFPVNRTEIYPEYRDNPSELRKI
                     LETVSSVKDDPYATITEVYIKGFASPEGTYKHNTYLAEHRAKALIEYVKGLYHFEQAR
                     FTVDFEPEDWAGLEKRVENSSLADKEELLAIIRADEPKDYDRREAKLKALNGGASYRV
                     LLRDIYPALRHSDYAVRYTIRSFTVEEARELIYSDPRQLSLNEMFQVAQTMEPGSDAY
                     REVFEIAVRMYPEDPVSNLNAALTAIDAGRLESARRYLAKTSNSAERTLAEAAIAMLE
                     NRLDEAEALLGKLSDNPSMASQVEENLRQIAEKRQE"
     gene            complement(31305..31895)
                     /locus_tag="ACZPB4_07570"
     CDS             complement(31305..31895)
                     /locus_tag="ACZPB4_07570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3575 domain-containing protein"
                     /protein_id="HIR1098114.1"
                     /translation="MKKTIFMLFLLAVPFLSRAQGVPVEGKGSMIGIKSNIPYWATAT
                     FNLGAEVYLARHWTLELEAGLNPFSGKNDDGSYGRSLKHLRLHPELRYWFCETFNGHF
                     LGVHTPYLLYNVTDIKWLGTEGERHQGWGAGAGISYGYSWLLSRHWNLEATVGVGYLY
                     LKSDKYPCANCGRKQEGIKKHYFGPTQAAINLIYQF"
BASE COUNT         8796 a         7772 c         7192 g         8545 t
ORIGIN      
        1 catttctgaa gcgccgttct ctctcgaatg cgggtgcaaa agtaatgcta taaaacatac
       61 ggtccaaatt tatcgggcat tatttttcaa gttttttttc acgaggggga tcgcatacgt
      121 taataatacg tcgatatcca ttcttggctc atgtggccca ccacgtggcc taacgtgtca
      181 ccacacgcac ttgaaacaag tgctccacga gtacattcgc acgtaataaa aacgatgaac
      241 atcatcttgg ccccgatagg aaatcacaca gaaaaaacgg cttttagctc atgaaatcat
      301 gcgaaatgca cttggtttta gtgctttcgg atcacgtaaa cgtgggtaag gacccattat
      361 atcgcccccc aaagacccaa aaagccgaag agggaagaac cacacaaaca actgtatatc
      421 cacatgttaa ggcatcagga aaattccccg gtaaaaatcc tagggcgcaa aaggcgcatc
      481 tttacgcttt caaagaaaca tttttagaaa aataatattt acatcactct acagacaaga
      541 ggggtataaa cgttatttac agaaaaagtt ttagaaacat acataaagat gcgccctttg
      601 agccctaacc tatcagcaac atccctgata cgggatacaa aaaagccaat gggacacggc
      661 cgcaaagcca ttgagacaac acctctatcc cattgacttt acaaacctat ccctttgaga
      721 taccaaccct atcccattga gatgctattg acaaccgggc acttaaagaa caaaaagtga
      781 atgcacaacc gtatattcct attcaatgaa cgtgaatgca ctaccgctga aagaatacgt
      841 ccttgcccat tctccaaatt gacgatttca aatctgtcct cttccaagtg ctccatctcg
      901 attttcccgt catataattt aggccgccct cttttacctg taggctcttc cgtgatgaga
      961 taacggaaat aggcgtcatc tctaaatcgg ctgattacat gaaatcccat ttcaaatgcg
     1021 ccatacacaa aggtggattt ggagaagtag gcatccgcaa ccacatagtt tgccagtcgc
     1081 tgaagtgttt ccttgcgtgt acacggcaca tgtagatacc agtctattaa tgtgtatgta
     1141 acttgctccg gtgtttttat cggcggtgtt tgaaccactt ccggatggaa gcaggcatga
     1201 aagtccgata gcgttgttca ccaaagcgac cataacgacc cggttgaagg aaattaatcc
     1261 gcccggggat aatcaaatat aaaagtagga cttcaagcat aaacttctca cgccatttgt
     1321 ttagctttac cgctgattta agcagcacac tatttattag ctctaaatat tggtcaagtt
     1381 cgttcagatt cattttttca ggatgtggaa acccttaata taatgaatcg ggaggacttg
     1441 acctactttt tatttgttaa ttcaaaactt aacgaactat tgcataggga agatctccag
     1501 aaattggcag aagaagataa tcccatcata atattaatgg aataattttt ggtggtacga
     1561 gcgaactgtg tcaactaaat atttttcatc cgttgtcata tccggctgag ccaaatagac
     1621 atgaacctat tatacacgat atacccatcc ggttgcctca atataaactc cttatctatt
     1681 aatatcctta aggaagtatt cacgttactc accgccttca aatcatactt tttgatgaag
     1741 gcggcagcat tgacctcccg gacgatccct tccttggcga tcgctttcaa tagctggatt
     1801 tgattaaatg tcaacaattg gaaataagtc tggtaggtat attcttcttc ctgtaggatc
     1861 tccatcatga gagaatcaag aagctccgga gaaagtgttt tttccggtaa agcgaagaga
     1921 cggttcaaaa gatattgcac ataccaagta tgcccatcta cccatgtgta caccttatca
     1981 aatatttctt ccggaagctc cttcccttcc ttctcgaaga aagaatgggc aaaggaaaaa
     2041 tacacctcct tgctgatctt gtctaaaaat aattttgggg tggattgata gaaggggcgc
     2101 ttgattgaga agaatatata ttccatcaag tgctttttac tccccgaaaa gataaaatga
     2161 acattcggca aaaattgaat ataagaacgc aataggcctt ccaccccttt ctcaggatat
     2221 tccatgattt gctggaactc gtcaatagcc agataacatt ctcttccaga ctgccgcaag
     2281 tagtcgaaaa tctccttcaa cgtagattgc gagaggttat ccggcttacc aacgtgatat
     2341 ttctcccatt atgaagagcg gataaaatca cttctgtctc tttctcccga tcacaaaaat
     2401 attctggacc ttgataacca actattaaaa aaggattatt catattcagc atcttatctg
     2461 cgttacgcaa ttcacgtaac gcaaattacg taataaaaaa ccagaataac aagtaaaccg
     2521 actactactt acatatcccg acactcaccg acactcgccg attcccgttt ttcagagggt
     2581 ctatctttgc attgtcatta gtaattaacc ttttaaaatt caaaattatg gcagtgaaat
     2641 ttaaagtagt aaagcgtaag gtattgaacg gcgcagagaa agactcagta aagaactacg
     2701 cgatcgctaa aacgtcgggg acttcggacc tcaacaaatt atgtaaactg atttgctctc
     2761 gctccacgct ttcgtcggcg gacgtgaaag cggtgctcga ttcattaaac tgggcgatgg
     2821 atctggaact gtcctccggc aacgtggtgc aattgggaga atttggtaac ttccgtatgt
     2881 ctattaactc cgaaggaacg aatacgcccg aggacttcga cgccaccaag ataaaggggg
     2941 tacgtattat ctttttcccg ggctcggccc tgcggactac ccgcaatgag gtgaatttcg
     3001 agcctctgga ggttacgaaa aagagcgcag gttctgatag cgaaagcccg gacgagatat
     3061 gagaaaaatt gacctgatcg tgattcattg ctcggcaacc cgtgagaata cggattatag
     3121 cccggagcaa ctggagagtg accacaaggc acggggattc ctccgtgccg gttacaactt
     3181 ctacatccgt aaatcgggag aagtggtgaa cctgcgcccg ctagagcaaa ttccggctca
     3241 tgcgagagga cacaacaaac acagcatcgg gatttgctac gagggtggac tggacatcac
     3301 cggacagtca cgggataccc gcacacaggc tcaaaagacc tcgttgttac gtttgatccg
     3361 gcatctctta atctgctttc ccggctcatg ggtctgtggg caccgggatc tctcggagga
     3421 cttaaacgga gacgggacga tctcgccgga tgaatggatc aaacaatgcc cctcattcaa
     3481 cgcaatctcc gaatacaaag aactcgtgta tgagctacga aaaaaataag taaaaaatcc
     3541 atgctcccac taagggtttt caaatttggt tgcgactatt agtatagaaa caacttaaaa
     3601 tggagaatag catagatcat attatcacaa ggatattaag tggcaacagc tcctcggaag
     3661 attttctttc gctgagcgaa tggctgaacg cagacgaaaa gaacaaaaaa gaatttcggt
     3721 tgctaaagag ttattgggat gcggaagtct cgttcagcca ttccttaatg cctaatgtgt
     3781 ccctcgataa tttgagaaag aagatcgacg atcaaagcag gcaaaagaga ttgaggctga
     3841 tccgtttcat cgctactccc attgcggcgg caatcgcctt tcttgttctg tttttcgcga
     3901 caatacactt aaatacccgg gaagctaagg ttcagcaatt ctatacctat ataaccgata
     3961 aaaataaatc tcattttacg ctagatgatg gtacgaagat cattttgaac cggaatagtc
     4021 gctttaccta ctctgacgca tacggtacgg atcagcgaaa ggttaatttg gaaggagaag
     4081 cctatttcga ggtggcgaaa aatccggaaa gacctttcat cgtcgatatg ggaaatgcct
     4141 ccatacgggt attaggtacg acctttagtg taaaagccga taaagggaag gatcagatca
     4201 cggccgtcct gctggaaggg tctatccgtt tcgaaagccc gacacaacaa gtcttactcg
     4261 ctcccgacca gcaacttaca ttcatccgtt caacgaacaa gattgatatc caatccgtca
     4321 acgcaaaaga aaatctggca tggaaagacg gcttgctaaa gtataaatca atagcgcttt
     4381 gtaccttgct gaatgagctt gagaaaagat acgagattcc gatccatata gaaaacaaga
     4441 gattgctgga cccgaatgtc actgtatccg gaacattcag tgaggatcaa tctttaaagg
     4501 agattttaca agtgatctct cgtagtttgc cgatcaaatg gtcacaaaga gatggaactt
     4561 actatattca ataaaataaa aatatcaaca catcttaaaa aacaagcaat gcctatgaga
     4621 taacacggat cctatctttc aaaaaaacaa aaccggctgc aaaaatacag ccggccccat
     4681 taaaaagaat taattcctgc ttctgctact ccacgaccaa attttgtggc agacgcatat
     4741 tatcaacctt ttatcagtac aaaaatatgg aaaatgtttc gtattatagg tcttttaggt
     4801 ccaaagactt aaaaaaaatg ctctcggtcc taaaaatgtc ctttatttta cttttcttga
     4861 cactgttcca agcggtagcg actaattcct attcacaatc tgtaacgatt tccgtgaaga
     4921 cggatcaagc cccgctaacc gatctattcg ctattataga aaaacaaagc gatttcttat
     4981 tcttctatgt ggattctgac gtaaagaacg taaaagtgag cgtgaacgca accgataagt
     5041 ccatagaaaa tatcttatcg caagcactac gcaacacgag tttgaaatat tcgatcgaag
     5101 gacgaaatat caatgtattt aataaaaaca ttgttgccca acagactaag aaacgcatca
     5161 ccggtgtcgt taaagacccg gaaggaaacg ctattatcgg tgctaacgta gtcgagaaag
     5221 gcacgaccaa cggcacgatt acagatctgg atggtaaata cgttatggaa gtatcctcaa
     5281 acgcaactct cgagttctct tatatcggtt acatgacaca gttgcaaccg gtaggcggca
     5341 aaaacgagat caatgtaaac ttgaaagagg acactcaaaa actggatgag gtagtcgtag
     5401 tgggttacgg tacgcagacg aaacgtgaga ttaccggttc tatcaccaac gtgaccgctg
     5461 aggatttcaa ccaaggtctg actcgtaacg cagcggattt gttgcaaggt aaggtggccg
     5521 gtttaacgat caatacaggt tccggcgacg taacgggcaa ctcgacgatt caattaagag
     5581 gtctatccac tttgcaaaac gaccaaggcc cgttaatcgt tatcgataac gtgccgggca
     5641 tggacatgtc tacggttaat ccgcaggaca tcgaatctat ctctatcttg aaagatgcct
     5701 cttcagccgc tatctacggt tcccgttcag cgggtggtgt tatccttatc acgactaaga
     5761 aaggttacgc cagcaaaccg accatcgctt ataatggagc gttcggtgta tctaccttgg
     5821 ctaacaagcc gaatctgcta acagcggacc aatggcgtag ctatacttcc tctaccccgg
     5881 gtaaggacgg taaggatttt gacatgggag cgaacacgga ttggttcgac gagatcacga
     5941 gaatcggttt ccaacaggat catgccgtgt ctttatcagg aggtggttca caccataact
     6001 atagaggttc cctttcttat atgcaacgtg aaggtatcgc acgcgataac tccatgaacc
     6061 gttacaacgc ccgtttccaa ttctcccaac gtgctctgga ggatcgtttg aaagtaagca
     6121 tcaccggcgt ggctaccgtt acagataacg cgccgaccaa tgcgaccaat ttcttacttg
     6181 cctacaatat gattcccgtt cgcccggtta agctagagga tggatcttgg ttcgacacac
     6241 gtgaatacga ccaaggaaac ccggtacgta accagaaaga gaatacacat aagaaccgca
     6301 tcaataattt ctatggaacc gctgatgtcg gttatacgat tatcgatggc ttagaggcta
     6361 aagttctttt agctaaaagc cggaatacgg aagatgagag caaatacaac agtatcgagt
     6421 ctcaagccgg ttacaacgat ggcggtaagg ccgaacgttg gtccagacta cgtgataaag
     6481 acttgatgga atggaccgcc aattattcag ctgagttcaa taagcataag atcaatgcct
     6541 tgatcggtta ctcttgggaa gaagagaatt atgaggagac tcacgtacag acccgtggtt
     6601 tcgtcactga tttattaggt gctaacaatt tagccgcggg acaaaatctg aatccgggag
     6661 acgcagagtc tcaaaaatgg caaagtcgcc tgatctcttt atacgcaaga gccaattata
     6721 gcttcaatga gaaatatatg ttgacagcta ccgtacgccg ggatggttct tctaaatttg
     6781 gaacgaataa caaatggggt accttccctt ccgtttccgt gggttggaat gtcacccaag
     6841 agtcattcat ggaaaaagta aactggctta acgacttaaa gttaagtgtc ggttatggta
     6901 tcactggtaa tcaaacagga ttggacccct acaaaaccct cgagctttac ggcacagatg
     6961 gtgtatatta tgataccggt tcttggctac cttcttataa aatcagccaa aacgcaaacc
     7021 cagacttaaa atgggaacag acagcgatgt tgaacatcgg acttgatttc tccgtattgg
     7081 atagccgcct aggtggtcgt atcgaatggt ataacaaaaa gacctctgac atgctttata
     7141 cctatccggt gccaacccct ccttacctat atagcgagat catggctaac gtgggcgata
     7201 tgcgtaatac gggtatcgag ttgagtttga acgcagacgc tatccgcacg aaggatttcg
     7261 attggaacat ctccttaaac ttggctcata atgagaatga agtgactcgt ctatccaacg
     7321 acgtatttac aatggataag atcttattag gtgacgtatt catccggggt ggaagctcca
     7381 gcggtacaca cgtattggaa gagggacgcc ctatcggaca attctatggc ttggtttgca
     7441 acggtatcga tgagaacggc agatatatca tggtagataa agacggtgac ggcgagattt
     7501 ccgatccggc ggattatgac tacatcggat ccgctcaacc gaaactgaca tatggtatca
     7561 ccaatacttt ccgctacaag aattttgatt tgtcattctt cttgcgtgga acgatcggta
     7621 atgatatatt gaacgcgacc cgcatggcat acgctcaatc cggattcttg ccgggaacaa
     7681 acgcattgga tgatccattg acctatacgt taagcgaaac tccaagattc tccaactatt
     7741 acttagagaa aggttctttt atgcgtctcg acaacttgac tttaggttat aagatcaaag
     7801 cattgaatgg tatccgtgtt tatttcacgg cgcaaaacct attcgttatc acgaaatata
     7861 aaggtcttga tcccgaagtt cctatggatt caggagacgg tttgaccccg ggtgtagaac
     7921 ctcgtgaatt ttatccgaag gcacgcacat tctctgttgg attaaacttg aatttctaat
     7981 acacaaacag taacgatcat gaaaagatta ttcaaaaata taatatgtgc cgtactcgct
     8041 ccggtagcac ttgtctcttg catggatttg gacgagaacg tatacgacaa gcttcctacc
     8101 gacgaattcg ggacaacaga aaagcagatt aatgcgatca tggctccggc ataccaatcc
     8161 ctaaagaaca tgctggctta tgacggtcct tggggagcgg ccgatatgac agccgatatc
     8221 ttgatagcac cgacacgtgt aggtggcgac tggtgggacg gcggacaata catggaacaa
     8281 tgtatgcaca gttggaaacc gaactcttac tccgtagaga attgctggac atattgtacg
     8341 gaaggtttaa ccacagttaa ttccgtatat aatattatag agaaaagcga ggcgatgagc
     8401 gatgaactta agcttcaata cttgtctgag ctaagaggat tacgcgcttt ctggtattat
     8461 gtaatcgtag atattttcgg taacgctcca ttagtgacag attttgagga tacctccttg
     8521 ccctccatca cgagccgtgc ggatctgtat aaatacgtgg tgaaggaatt aaccgagatc
     8581 atcccgaacc tgcgctccga tgtatcagac gccagctacg gtaagttcac gcaaggggct
     8641 gcccgtatgg tattggcaaa gatgtacctc aacgccgagg aatggatcgg cgagccgaac
     8701 tggaaaggtg tagtggagca gtgcgacgag atcatgaaac tcgaatatat catcgagccg
     8761 aattggaaaa ccaatttcga ggttcataac gaggtatcac gagagattat tttcccgatc
     8821 tgctacaagg catctgatgc ttggggtaac tccattcatc tttggacatt gcattatctg
     8881 gatcccgatg tattaggttt caccggcggt atgtggaatg gtatcaacgc ccagccggat
     8941 tttgtccgca catttgatac ggaagatcct cgttacgaag gttcgttctt gattggcccg
     9001 atgatcgacc ctagcacggg agagattttg aaaacgaccc taggacatga cttgatccat
     9061 acgatcgact taaatgtggt accgggaact gagaaaaccg atgcggatgg taacttaacc
     9121 ccgtggggcg aggttcacca agaagacggc gcacgtatca ataagtgggt atatgagaaa
     9181 ggcatgcaaa ataccaatat ggagaacgat atcgctatct tccgtctggc cgatgtatac
     9241 ctgatgaaag cggaagcctt ggttcgtatg ggcggggatc tcggtgaagc tactcgtctg
     9301 gtaaacgcta tccgggaaag ggcttacggc aattccgatc ataattacac gagcgtgaca
     9361 ttggacgata tctataacga gcgtggttat gagttggcat tcgaatttgt ccgccgccaa
     9421 gatatgatcc gcttcgggac ttatctgaaa ccgagatata tgaagccgaa acagactccg
     9481 gaatatcgta agatcttccc gatcccgttc aaggcttggc agaagaataa taatttggtt
     9541 cagaacccgg gatatccggc attctaatca tatcagtctg tttttaatat caattcttta
     9601 gaccccaatt caattattaa tcataatatg aacaaattta tgaaagaggt aaataaacaa
     9661 tcctgtccga ctggaatctc gagaagggaa ttccttggga tggcagccac aggtgctgcc
     9721 gcccttacga tcctgcccag ttttaccgta gcgggattag gacacgtagc tcccagcgat
     9781 aagctttata tcgcgaaaat aggctgtggc ggtatgggag ccgccgattt gggtagcttg
     9841 atgaatacgc cgcacaaaaa cgcagcgatc acctgtctgt gcgacgtaga cgaccgtcag
     9901 tctgccgacg ctcgtaagaa atacccgaag gcgaagtatt tcaacgactt ccgtgagatg
     9961 tacgacaagg aaggcaagaa cttcgatgcc gtatgtatct ccaccccgga tcataaccat
    10021 gcgatccaag ctttcggcgc tatgcggatg ggtaagcacg tatatctgca aaaaccgatc
    10081 gcgcacgata tttacgaggc acgtatcctt accgaggccg ccaagaaata caaggtcgtg
    10141 acccaaatgg gcgaccaagg taactcttgc gacggtatgc gtacccttcg tgaatggttc
    10201 gaggcagatc tgttaggtga catccagaag gtatattgct ggaccaaccg tcctgtatgg
    10261 ccgcaaggta ttccttggcc gagccagaag cctgaggttc ccaagggatt aaattgggac
    10321 ttatgggtag gtaccgccga gtatgtggat tatatcgata atcttgttcc gttcaactgg
    10381 cgtggttggt ggcgtttcgg tacaggcgct cttggagata tgggttgcca catcatcggc
    10441 cctccattca aattgcttca attaggttat ccgactgagg tttcttgcag cacgaccaat
    10501 gtctactccg gtatcttcga ggaggcttat tatcctgaga gttgcccggt agccagctcg
    10561 atccgttata aattcaagaa gaaagacgga agcgacctga atctctattg gatggacggt
    10621 ggtatcatgc cggagcgttt cgaggagatc gatccggatg cagacatgac ctgcacgatg
    10681 ggagacttgg atatgatgga cgtagaaggc gcaaccgtat tcgtaggtac gaaaggtatg
    10741 gcttcttgcg gctggggcgg ttccgacccg agattctggc caaagggaca gaaggcgaac
    10801 aagaaaccgc tgttcgacaa ggacgtgaac attcctcata aatacaaacg tatcgaaggc
    10861 ggcacgaacg gtcattactg ggcgtggatc gactcttgta tcgcaggata cgacaaggcg
    10921 gacgtagaat caccattcga aggttacgcc ggtccgttga cggagaccgt attgatgggt
    10981 aacctgatct tacgcagcta taatatccgg gaacaagtga aacataacga ctcgatctac
    11041 ggagaacgcg agggctttat ctatccggga agaaacaaga ctttccagtg ggacggagcg
    11101 aacatgcgta tcaccaactt cgagcaagcg aaccaattca tcaagcggaa ataccgcgat
    11161 ggatgggagg aagtaaaatt ataggaaaga tttgaccccg taattctacg aggtcaaatc
    11221 aaaaagaaat gttttgacct cgctgaatta tgtagtcaaa tcatataaaa aagatttgac
    11281 ctcgtagaat ttagaagtca aatcatgagc aaataaaagg ataaacctaa catttaccta
    11341 acaaacaact cacaaacaca taataaaatg aagaagattt atagcagcat catggtagcg
    11401 gccctattcg cgtcggccgt atcctgtact tccggaaaca gttctagtgc cggcagtaca
    11461 caaacagcga aaggacaagc atgcccgaac gacggtattc ccgaaggcgg cgagtggatc
    11521 accatgttcg acgggaaaac cttgaacgga tggcgcggct attgccgtca ggatgtaccc
    11581 caaggttggg tggttgaaga cggatcgatc acctataaag gtagcgacaa taaggcagac
    11641 acgggcttcg gcgacttgat ctacgacaag aagttcaaaa atttcgtttt cgagatcgaa
    11701 tggaagatcg acaaggccgg taatagcggt atcttctata cagcgcaaga aattgagggt
    11761 acacctattt attactccag cccagaatat cagttactcg acaacgagaa tatgccggac
    11821 gcatgggaag gttgcgacgg taaccgtcag gccggtgccg tatatgacat gattatgccg
    11881 gatccacaac ccgtaaaacc gtacggaaac tggaacaaga cgagaatcgt tgtctataac
    11941 caacgcgtga tccattacat gaacgacgtg aaaattctgg agttccaatt tggtaccccg
    12001 gtatggcgcg cgttagtgga tcatagtaag ttcagcaagt tcagcacgag tccggagaaa
    12061 tgcccggaag cttacgactt gatgctacaa tgcggaaaac aaccgggtta catcggtatg
    12121 caagaccacg gttatggtgt ttgcttccgc aatatccgaa tcaaagagct ctaaaatcgt
    12181 atgagaatag agatttgtca atcttatgag gcattaagcc ttaaggcaaa agagattgtt
    12241 acctcagagt tagggcagca caaggcactt acgctttgtg ccgccactgg gggctctcct
    12301 acccggatgt atgagttgct ggtagaggaa gccggtcgcc aaccggaatt attctcccaa
    12361 ttcacggtac taaagctcga tgaatgggga ggaatcccga tggatcaccc gggtacgtgc
    12421 gagtcgtatc tacggaacta tttcgtaggt ccgcttcaaa tcccggaaga ccggtatata
    12481 gcgttccaaa gcgatccgga gaaccctgag gcggaatgtg agcggatcca acagatactg
    12541 gatcaaaaag gccctatcga catttgtata ttaggaatag ggatgaacgg ccatatcgcc
    12601 ttgaacgagc cggctccttc cttgcatacg aattgccatg tggctcatct gtcccagaaa
    12661 tccttgcaac atcccatgat cgccggggat acggagaaac cgggatacgg actgacattg
    12721 ggcatggcga atatctttca gtcacgcctg attatccttc ttatcaacgg gataaagaaa
    12781 agggagatta ctcaagcttt ccttgaacag aagatctcga cggagttgcc ggcctcctta
    12841 ttgtggctgc acccgaacgt gatttgcctg atcgacaggg aagcggcgca tagttctaat
    12901 taagctttta caattatcat gaaatacgct atcgcattag acattggagg aacaagcata
    12961 aaatatactc ttgtgaacca gaatggcgac attctttacg aatcgtcgga aaccacacaa
    13021 tcaaaagaga atccacgccc attatccgat atcataaaaa gtatcgtacg gaaaatgaca
    13081 gactacgccc gttcccggga ttgggggatt tacggaattg gcataggtgt accttccgta
    13141 gtagataagg gggtggttct ctttgccaat aatcttcctg aactggacaa ccaacaattg
    13201 gatcttgcgt tagcggaatt taatctaccg gtattcatcg acaacgacgc aaaccttatg
    13261 gggttgggcg aggtgatata tggggcggct aagggtctct ccgatatcgt tttcttgacg
    13321 atgggtaccg gcataggggg cgccttgttc ttgaacggcc ggctttatgg cggctaccgg
    13381 aaccggggca ccgaacttgg gcacttaatt attcatggtc tgaatgggaa tcaatgtact
    13441 tgcggagcgt ccggttgcct agaggcacac gcttccgtaa gtgcgttgat cgccttatat
    13501 cggcaattat tggagaagaa cggacgggag ataccttccc gtatcgatgg aaaatatata
    13561 gtagagcgct ataaagctca agagaaagag gccgtactcg ctatggagga tcatttccgg
    13621 aatctgtccc taggcgtagc gagccttatc aacattttcg ctccgcaaaa ggtgattatc
    13681 ggcggaggca tttcggaatc cggagatttc tacattaata atatacggga acaggtctgg
    13741 aaattcgtga tgaaggaaac ctcgtacttc acgactatcg aacttgcccg attaggaaat
    13801 aaggccggat gcctcggggc ggcggcattg gtgtttaatc attgaatcta tctatcatga
    13861 ataagaataa ttggatcgta ctcctcatct tgtgtatttg gtttgtcatt tcttttgtta
    13921 ccaatatatt aggccctatg ctaccgatga ttatcgatag ttttgggctg agcctgacat
    13981 tggccgcatt cttgccgttc tcgtttttct tggcatatgg catcatgtcc atcccggcag
    14041 gaatgatcat cgagcgtttc gggggaaaga tttccttatt ggtcgctttc agtctggcgt
    14101 ttttgggtgc ggggcttttc gtcatgttcc cgacctaccc tatcgtattg acctcccttt
    14161 tcgctatcgg tctgggcatg gcgatgctac aggtgatcat attgcctttg atgcgtgagg
    14221 cgggtggaga gaaaaaatat gcctttaatc aggtattggc ccagatcgta ttcggggccg
    14281 cttctttcat gagcccgttc gtcttggccg gacttatgcg gaaattaacc ggtgaggatt
    14341 cggcaaacga cttcttcatc cgtttcctca aagggataac gccggagagc ttaccttgga
    14401 gctcgctcta ttttatcttt acgattgttt ttgtcatcat gttagtggtt atctcttatg
    14461 tcaaattccc gaaagtagaa ttaaaggaag atgagaaggc gggaacggta cagaattata
    14521 aggaattgct caggcaaaaa caagttatat tctatttctt ggggattatc gcttatgtgg
    14581 gaaccgagca aggattggcg aattggatga gtcttttcct gaatatgtat catggggtca
    14641 gcccggaagg agccggggct actacggttg cttggttctg gggattgatg tccatcggct
    14701 gcttgttggg attggtgatc gtaaagttaa tcgactcaaa gctgatgtta cgtattttct
    14761 cgatgatagc gatccttaat ttatcgatag cgctcttcgg tcctacgcaa gtagcgatta
    14821 tcgctttcgc ttgttgcggc ttctcgatct cgatcatgtt ttcggtgata ttcgccttag
    14881 cccttaactc cgtggataag catcatgggg ctttttccgg tatcttgtgt acgggtattt
    14941 tcggtggggc attgattccg ttcatcattg gtggacttgg agatctgatc gggttgcgct
    15001 attccatgtt tttcctattt atcacgctgg gctatatctt gagtatttcc tattgggcaa
    15061 aaccattggt caagaatgag accgtcagcc ttaaagaatt gttgaagcag ttaaaccgta
    15121 caaaataaat atgtatatct ttggcctata aaattatcat ccatgaaaaa agaatcaatc
    15181 tacctcattc tggcattttt tatactttgc gctcactctt tatacgcaaa taaaagcgtg
    15241 cgattgtctt ctccaaacgg aaagatcaag ttctccttgg ttttggataa gaatagcccg
    15301 gtatacagcg tagcgtttaa taaacaaacc ctgatccaag actctccgct aacgttgact
    15361 ttcgataatg gggcgttcgg ggaaaatgta aagatcaaca aacccgtgtt cagtacgaag
    15421 gaagagacct acgaattgat cgttggtaag gcgaaacata tacatagcct ttccaaagag
    15481 gtaatcatcc cgctagagga aaccgttcag ccttttcgca agattaatct ggtcttgagg
    15541 gctttcgatg acggtatcgc cttccgctat gagtttccga agcaaaaagg atgggattcg
    15601 tatatcatgt atgacgaggg aaccaccttc aacctacaag ggaatccgaa cgtaactact
    15661 ttattcctcc ccaactacca aagttcccac gaaggtaaat atacggtcac agattatgcc
    15721 gacatggata ataaacgatt gatggatatg cccgccctat tctctttccc gaaccatgtt
    15781 tatatggcga ttaccgaggc ggcggttcgt gattacgccg gtatgtacct atggaaagaa
    15841 aacgggactc ttctcgggaa actatcacct aaactgggac aagagcgtat caaggtagag
    15901 gcatccctac cccatcaatc tccttggcgg gtcttgatga tcagtgatca aatcggttcc
    15961 ttgatagcgt ccaatatcct tacgaatctc aatgagcctt gtaagataga ggatacgtct
    16021 tggattaagc cgggtaagac tacttttacg tggtggaacg gaaatgtcgt tccggatacg
    16081 actttccttg gcggaaacaa tttccccacg aataaatatt acattgattt cgtagcccgt
    16141 aacggattgg attatcactc gatctacggg aacgccgagc aagcttggta tgacgaggat
    16201 ggagccggat tcggttctcc gggtcctaaa gcggacatct tgaaagtcgt tccgagcctc
    16261 aatatgcagg agatttgcga ttacgccaag agtcaaggcg tacgtatcca tttatggacc
    16321 aactggaaac ctctgtacgc aaagatagac gaggctttcg cccaattcga gaaatgggga
    16381 atcgccggca tgatgatcga tttcatggat cgagacgatc aggagatgat ccgcatccaa
    16441 gaagagttct tggcgaaggc ggctaagcat catctattcg tgcaattcca cggagcttgc
    16501 aagccgtctg gattgagccg tacctatccc aacgagttca cccgcgaggg tacgcttaat
    16561 tacgagcatt gcaaatggga taaggatacc gacgcagatc atgacatcca tatgcctttt
    16621 acccgtttat tagcgggagc gactgattat catttaggag gtttccgctc tttgccaagg
    16681 gataagttca agaaccaaga acgtaaccct tacgtaatga gtacccgctg ccatatgtta
    16741 gcgatgtacg tggtattaga gagctatctc ggcatgattt gcgatacgcc ggaggcttac
    16801 gaaggacaac cgggattcga gttcctgaaa gccgtgccta cgacttggga ccaaacagtc
    16861 gttccgaacg cttccgtcaa tgaatacgta acgatcgccc gcaaaaaggg agaggattgg
    16921 tttgtcggta cgatcaataa cagccaagca cgcagtatcg atgtagacct caagttcttg
    16981 gataaggaca agaaatataa gataacgatc tataaagatg ctgaagatac gaatatagac
    17041 ccgaacaaac tcgtaaaaga ggttgaggag atcacctaca gggataaaat cacccttccg
    17101 ctggcctccg acggaggatc agtctttcat attcaaccat ctgacgtaac tcatccactg
    17161 caacctgggt tgcggtggta ctgcaaggct gatgcagtaa tactgcaacg cccatacagt
    17221 aacgctgcaa cgcccgtgca gtaacaagac acaaagcttt cggataaaag caagtattgg
    17281 aggaaccgga acaattgatt acttttgtgc tcaaaaatag ataaatgagt tacaattgga
    17341 atacacggac ggaacttttg ttcggagcgg agcatatgga gtgcttatcc cgtagccatg
    17401 tattggtagt tggcctagga ggtgtgggag cttatgccgc cgagcagatt tgtcgggccg
    17461 gagtaggaaa gatgacgatc atagacgccg atacggtaaa cgagagtaat atcaaccgcc
    17521 aattgcccgc ccttcattcc accctaggga tgccgaaagc cgaggtcgtg gccaagcgtt
    17581 tgcttgatat caatccccag ttgcaactaa ccgtcctgaa tgaattcctg cgagacgaac
    17641 ggacggagga ggtactctta tcggcccctc tcgatttcgt ggtagatgcc atcgattccc
    17701 taagtcccaa ggtatacctg atgtaccaag catatatcca taagatcccc atcgtgtcct
    17761 ccatgggggc gggcgctaag gtagacccat ccttggtacg gatagcggat atctccaaga
    17821 caatcaattg cgccctcgcg aaagcggtgc ggaaacggtt gcgtcctcta ggcgtaagca
    17881 aggggattcc cgtcgtattt tccaccgagt tcgccgatcc ggacgccgtg atcgaagttg
    17941 aaaacgaaac atgtaaacgt acgaccacgg gaacggtctc ttatatgccg gcaacgttcg
    18001 gttgtttcct tgcctcgcac gtcctaagaa acttgatatg atacaaaccg aaggaataac
    18061 gaaaagtttc ggtgccttac aagtattgaa aggcatcgac ctcacgataa acaagggcga
    18121 ggttgtcgct atcgtaggcc ccagcggggc gggtaagaca accttgttgc aaatcatcgg
    18181 cacgctcgac gcaccggata gcgggcgact ggttatcaat ggcacggaga caagacgatt
    18241 gggcgataag gaattggcgg ctttccgcaa ccggaatatc ggcttcgtct tccagttcca
    18301 tcaattattg ccggagttca cggccttgga aaacgtgatg atcccagccc tgatcgccaa
    18361 ggagaaatcg gccatagccg agaagcgggc gaaagagatg ctggacttct tgaaactctc
    18421 cgatcgtatg gcacacaagc ccgccgagct atccggcgga gaaaagcaac gggtagcggt
    18481 agcccgtgcg cttatcaata acccggcggt tatcctcgcc gacgaacctt cgggaagcct
    18541 cgataccaag aacaaggaag aattgcacgc cctctttttc gagttaagag accagatgaa
    18601 ccagacgttc gtcatcgtga cgcatgacga acagctggcc acaaacacgg atcgggtgat
    18661 ccatatcaag gatggagtgg tagaaacgaa ctaacaacaa gggggtttat ttacaatacc
    18721 cgtagtttca ccgtcttttg gtcgtgggcg atctccgtgc ggataatgta gatgcctgcc
    18781 gggagatcga acgtataagt cggacgggcg ggatataagg tacgtaccaa acgacccatc
    18841 ggcgtaaaca cctgtatccg cttcaacgcc tcgctagcac tggccactat cctacccgat
    18901 acggcggaat agacagagat agattctacg ttgtccaccc cctcattacc ggtaggcgag
    18961 cccgcactta ggaagtaacg tccatggctg ctgccgtcca aacgcaaggt atacgtattg
    19021 tccgacaact ccgtactttt acgggtcacg gcatcgtaca ggtaaagcgt ctccgcccaa
    19081 tcgccgatac cctctatcgt cagtgtaacc tcccccttac cctcgccggc atatacgcca
    19141 aggggcactt ggtcgatccg tcgtactacg ttcacaccca cggcacgagt cccggcgata
    19201 gtgtacacct gcgggatctc ctccagttcc gtatccagca agattacggc atccttatct
    19261 gcctcatagc tattcgcggc atcatcctgc cgcgtcaaca aggccgtgct acgatatgca
    19321 tcccgctctg ctgtcagcct caataccggg tttttggccg tagcggtacg taaggaagaa
    19381 gagaccttct ccgactctcc ttgcatcatg gagggatcga aatgaaccac cttcagatcg
    19441 gtaccggttg ccgtaccttc cgctttcgtt tgagccgcat ctttcagctc tacgaagaag
    19501 gcttgcatgg aggcgataac ggctccggat gtagcatcag taacatttcc accttcccat
    19561 gccacatcag gtgtaccgac aacaagcccc tccttcacat ccaatgtcca atatttttgc
    19621 tctaagatag cctcattctc tttcaagaaa cgaacgatat ccaacggata catataagga
    19681 ttacccaaca ggaagtgctt gccgtcacca tcagcaataa cacggacggt tccattatcc
    19741 gtattccacc aatcttccgt tccattcaca tctgtcaata ccaccttgat cgacttgtta
    19801 tctgccagtt taccagcatt gatccgattt gctaaagtcg gggctttggt catggcggct
    19861 ctcaatgtag cgcttttcgt atccggtttc cacggttcat atttgtagga gtcatccgct
    19921 ttcggcaggc gtaccaatac tttctcacct aagccggtcg cattcttctt ttctacgctg
    19981 gcatagaatc cctttcctaa agcgtagggc acattcacat cgttatattc acggctccag
    20041 ttggattgga ctacctcgta atgagttgta tccaaaccat tctccggaaa agaaactatt
    20101 tgatctgctt cgctcttcgg cacgtacatc gtgatcgcct tgtcccaagc tttctggtag
    20161 aaggctgggg cttggcggtc gttgtcagcc gtgctgtagg tgatatcggc gaaagcatag
    20221 gtgttctgac ggcccgtgtt cttcacggtg tacatatcgc cggcgaatac gctttgcagg
    20281 ggcgatgcca tccaatattt cgcatcaggt gtcatctcga attccacatg ggcagtgtcg
    20341 tacgtcagga attgctgacg gcgtaactgc gcctcgggtt tgaaatagat agcctttacc
    20401 ttatttatat agtacggggt tacgatcgta ttatctccgt ctttgtctac cgccatatca
    20461 tattggatat actcggtagc ctttgatgag ttcgcttcgg gaatctgtaa caaatgatct
    20521 ttcgtctcca agccttccaa ttccagcatc tgcttttccg ggatcgtgat acgggtgaaa
    20581 tgaagcgggg cgaaggcggc ggtcaagtct gcatcattgc cgttggcgtc tgttttatct
    20641 tctccgtttg gatctatgta caattcccct ttcgtagact gatgccagtt tgcgtcatta
    20701 taccatgcct cagcgtcctc accggtgttc gtacccttcc aagtcagata ttccggcacg
    20761 atcttgataa gtaaggtagc gtatccttcg caagagcctt ttacgaaagc ttcgtcctta
    20821 tattcaccga atgggatata gagggcataa atctggcctt cgtcaaaatt tgtataagct
    20881 ttatcgtcaa aagtcatgga gaataatcca ccgccatagt cagtttcacc tgcctcattt
    20941 ttacttttag ctttcgcaga caactttgtc aaattaccca cctttgtata agtagcccct
    21001 tgccgcaaga agatatccgt agtattgctt tcgggcagac ctaattgatt ggattctgtc
    21061 atacccatct ttaggccatt gctttggata ggaatattgg ttatgctttt ctccatgata
    21121 ttcggcaagc caatacgcag gggaacattg ggataatgct ccattccttc cggatacttc
    21181 acgtccggga aaccaacaag tagtttcggg gcgggagcgg ctttcagtga tcgttcttga
    21241 ggtctatcgc agaaaagcca aagtctgtcc ttctcgggaa tactctccgg tagataagga
    21301 atcgctacca ctttttttac ccaacgaaac tccgcatatc ccaaattccc gccaatcacc
    21361 aatttcggct ctgtatctac atcacctaaa agcaatgtct tcaatttcgc aataagcgca
    21421 ggcttatctt tatatgcgtc taatttttca taatactcaa tcaaattttt cgcggggaaa
    21481 gacaaagctt tctcggcatc gggaagggta tttctataag acttcaatat ctcttctaaa
    21541 gagaatccat attcatcata gaacgcagca aattccagcg agtctcccaa gaaccagtcg
    21601 aacgtatatg aataaccctt atatctatct acaaacttat ctgtctctcc agtcatcaag
    21661 ttgttgtcct tatcatatct ttcaacccac atggttgcct cctcaatctg gctgatccgt
    21721 ccctcgcaag cgatcatgcc ctccggcaaa tctgtcttgg tctttgccac gaccgtgaag
    21781 gaagggagta cggtgaaagg ggtagtcagc aagcaaggat cgttgaaact atctcccgca
    21841 tgggcattcg ggaaatccac gatttcatca ctagtaactg tcgtggccgc actaaagatt
    21901 accacatcat acctaccgga ggcggcattc tctttacttc cgaaattttg ctccccttta
    21961 tatttcaact cagtcttgtc cacatcaatg gcactcaaat ggatggtatt gctatttcct
    22021 tcatcccacc aaggcatacg aggacgagaa atacccatta ccgaacaaac ggcccgtatc
    22081 agttcttcgt acagattatt gtcattcccc tccattattc tatctatctg gttagatagg
    22141 tctttcggtt ccggaatctt atagtcccac tctgaatccg atttgccaca gagtacactc
    22201 aaattttgtt tcaagtacgc aatatactct tcttccggga atttatcccc atttgttttt
    22261 tgggcatgat ctagtatgtc tttttgccaa attttatgct cagcggcatc atataagaaa
    22321 tcattgatca tacgcaggtt tacgacaatt tgtcgtcgca tcgcagtttc atgatttgtc
    22381 agatcctcaa atccttgatg cttcaaccct tctttagtcg gaacgataat acgatacacc
    22441 ttgcttcggt tgttatagcg ctcattacta taatccttca aatccgtatt taatgtaatc
    22501 caatcttcag gcttctttat atccccattt tcctttttat cggtagctcc aatataaaca
    22561 tttccgatcg ttttattaag attctcattt cttttccttg gatctccacc catcaaacca
    22621 tagcggtatc tccatatatg ctttgaatct tccgttatgc tattccccat attcagatcg
    22681 gacaatacat ccggattaat gctccaaccc atattcttga gcagaagttc gtaatccgtg
    22741 gcaacggtca ggctggcaga agaacacacg tctactcgct ttacgtcgat ttgcggtatg
    22801 gagcgataaa tacgcagacc atcgatggcg tagtccgcac catatgaatg agctgtattg
    22861 ttttgtacct ccagataata tcctacataa tcatcaagcg attgtgacaa ggaaaatgag
    22921 tacattaatt gctgccattt accaatattg ttattagccg gccgcccttc cgaagtcgag
    22981 gtataatcag tcagtgcatc ccctgaagta aaacgatgta aaacaacttc tgtaccatct
    23041 gcttttaatc cgataaaatt catgtttaca ttaggaggta gaggttttcc ttcggcttga
    23101 gtatctttcc atgtcgtcat atcattcacc caaaagttca ctaaaatacc cgtatgcgca
    23161 cagatattac catccaacgg aattttcacc aaacgtcccg gcaaattggc cgcatccaca
    23221 taaaagaaat atcccaatga ttttttcccc gtattgtaat aagtccggtc atagattgcc
    23281 actttgggct tactttgggc acttgcaaac caaaaataag tctttccctc aaccttttca
    23341 ttattcgttg atactttttc cacatccgct gttcgaaaca aaccatattg gttttgtaag
    23401 gtctgaatcc gattatcctt atttggttga atttgataat taaatggagc atatcccgtg
    23461 atctccggat ccaaccattt acctttatcc tctttattat cagaaaaacc aatctttgcc
    23521 atattattaa cagagttcaa atcgtctaca gatatcgaat cattccggtc aaaatttata
    23581 tatcctattc tttcataaaa ctccggatag ttatccggat tacgccttgg gtcagaatct
    23641 ttttcttgct tttcctgtaa catgaaacca tgatcaccag agataagatt atatcgcacc
    23701 aacagaggac tcgctttcgt cttatcttta cccaccgccc gaatttctaa ttttacaggt
    23761 tgtgttccaa ccgttatcaa attatttata atctgtgtcc agcgattacc caaatctttc
    23821 cattcgccat tgtctttctt atattgataa gtttctccct gtactatttg atctccgtca
    23881 taccacgcat aattattagc gatcctaccc aattgtatat taatcgttcc attattttgc
    23941 gggacatata tggtttcatc cataaaagga gtggtttcat ccgctttaga atcttttatg
    24001 cgattcgcaa tttcgcttgc cggacgaatc acaaatttat aacgtatgga caaagtaggt
    24061 tcagtgaatg tagtcccatc caccttataa ttgttattta aactcacatc acaaacaaca
    24121 agatcttctt ttacattcac cgctgaatat tcaaccgtag aggctccgag agggacagag
    24181 ctatttatag cagttgtacc ttctatctta taaaagtctt tataaaaaaa taaagaagta
    24241 cctgcgtctc tcaacgagct tggatagaga tttataagat cctgtaaggc accaccctgt
    24301 acaaaagaac catctaactt aggatttata gccttacctt ttatattttc gcaacttaaa
    24361 ttaccttcat taagctgata ccaacgtaca taccaccgat agttcgcatt ataaaagcca
    24421 tcattattcc tcaactcagg aataaacaac tccctctctt ccccatctgc cacatacacc
    24481 gtatccacac gttcggtaat accggtttgg ggtgaaccat tcttataatt gatcgtgtac
    24541 gtctgccccc acgccggcac agccacacca gcggaaaaaa ttaacaagca agttaataac
    24601 aaggatttat atcgtaggtt gattgatggt ttcatccgtc aggtcctcct tttttagttt
    24661 attgttgtta tattatggtt gttatttgta gtttctgatc ttgatggtgt aggggatttg
    24721 catctcttgc ttctcctgac ccacataata gtttataatg agcgtgagga tgactgtagc
    24781 atccacgttt ccacccagtt cccgagtgcg gatcgtgaag gaacctttct ttccttcctt
    24841 gatcgaagcc tcgggaaggt agaaacgctg tttcttgtca caatcctctc cgtttacggc
    24901 cgtaatgaga cgtttctcgt cgctttttac ttggatcgaa ctgattttcg ctgtttccgt
    24961 aaccgttccc tcctgcggga gacctttgat cgtgaaatct cctgtcacgc cttctatgct
    25021 agatatctcg aaacggatcg acaagtcacc ggcggcttgc agggtatgct caacaggcgt
    25081 cagtatctgc acgcccgtct tctcgccata gaacaaggcg gtcgggtaga ccccgatggg
    25141 gagacgttgc tcggctactt ccaatttcgt cgtgatgttg gttatcaaga cagggatgac
    25201 cagcaggtca ttgcggcgta cgaagtcgaa gcccgtgagg tgctccgtac gagggcggcc
    25261 ttcgatctct acaccgaggt ggatgccacc gccgttctct ccgacggccg cattggtctc
    25321 aggaatgtag cgaatataag ctcgtttact accgttctcg ccgtccacat gtttggcttg
    25381 tatttctttt tcattatcac cgggtttgat agattcagta taaagatcct ctagacttac
    25441 tacaggagga ttcgcatctt tcggaaaaga tggagccaaa ggctcttcca agtccttgtt
    25501 atccttaaac tccaaataat tctcatttcc ccaaggcaag agccagatcg gcaggcttcc
    25561 cttgcggagg ttcatgatgt ccaattggtt tacggttatg gatttatcta agttattggt
    25621 tatctccact tgcaccttgc cgatcatgcg gatcaaggga atctcgaatt tgttctctgc
    25681 cggagcgggc aataccgtat gcttttgggc gtagctgctc ataggaatac gctttcgaga
    25741 cgcttcctcg cctccgaatt tacctttttt ctcctcattc cttgtatcaa tactcgttcc
    25801 cgagtccaat atcttcacct ccgacagttc cgccaaggaa tgggcttcgg taattttttg
    25861 atacaacgat gtaccgtctt ccaacgattg taaattggcg aacgcataaa aatggtatgt
    25921 gccaaagggt agtttcatct ccaccgtagt acgagaatcc tcattactga tatccggagt
    25981 ccatgttcca tctttgccgg atatatatcc ggcaaaatcc gcattctcat cataggccac
    26041 caccagccag ttcgtgatgt ctcgctcgta ttcttcatct tttgcccaga aatccgtctc
    26101 agtagtttca tccgccttcg tcatcatccc ttcggccttc gtcatcatcc cttcggcctt
    26161 cgtcatcatc ccttcggcct tcgtcatcat cccttcggcc ttcgtctgcg gcgggcgtac
    26221 cgaacgggat gtccgcaaag tgatagttac aacacaatgg ttcgggtcgt catccgggag
    26281 atcgcccccc cggtcttcac cacaagccat aaaaagccaa cagaggcaaa gaccagcggc
    26341 gaccgccgtc aatcggttat atatggtata gcgtctcatc attagcgata tttaataaat
    26401 ctctgtttac aatatgccat cgttgatacg aatcacccaa tccttcacct gtatcttgaa
    26461 gcaggcgtac cccacgatcg tagggtcttc cggatcggga ccatcgggat tatccgggtt
    26521 atcaggattg tcaggattat caggtcccga aggatccgga ggatccggag gcgtaggctt
    26581 atccggacaa tcggggcata ccttcggtgt aaggaagaag atgatagaat actcgtcctg
    26641 ccggtccaga tactcctgcg gggagatacg gtgcccctcc atcttggtga gaaggaggta
    26701 atcgttgagg ttcacgttca gcacatcctt ctcccatccg tgatgacgga tgatgaggcg
    26761 gtagttacgg cccgccatca ggcgcatggt gttcatctcg gccacggcca cgtattgccc
    26821 gcctacggta gcgccggggg tcgggtcggc tcccaactcc acgttctccg tataataagg
    26881 caggtagtgg atggtgggat cttgcagcag ggaattgtcg taatccatat acccgttgtc
    26941 ggccacgatc cggaaggaga agttgttcac gtccatgtcc tcacccatca cgttttgcag
    27001 cacgacccgc agcttgttgg tattcttggc gagtgagatg gtgtcggcct cgggcatgtc
    27061 gcgcgtcacg gtgaaggtat cgaggctatg ccaaagcggg tgcagctcgt tgggctgtgt
    27121 cgtattggcc tcgcgcaagg tacgtacctt gacgtcttgc gccctcccga cagcctgcga
    27181 cgtctcggca gggtcgttcc atgcgtaact gcccttgtcc agcccggccc aagtgactac
    27241 ctgataggta cccggctcca tgtcgagggc gatggagttc cgctcgtcca gctcgctctt
    27301 ctcgatccgc cgctggaaaa ggaagtttcc ttcttggtcg cagaagaaga gcgtaacgaa
    27361 gtctacctca tgctggaaag cgtcggcgaa tttcatatta tagtcgtact tgaaatacag
    27421 gcggaactcg caaagcggca gcgagtcgtc gtgtatccaa tcgcaagcgt atagccccac
    27481 ggacaaggca gctatgccaa tcaactgttt gcaggtatga aataaacggt tcataatcat
    27541 tttattaaga tacacagtaa tcctccgccc gtactaccgg aaatggaggt aaaccatgat
    27601 gcccattata aggttcttat gatgggcatc gtaaggttgc ttggatgggc agcataaagt
    27661 gcttacaatg cccatcgtaa gaatcccccg aagggtaaag ttataggata atgtctttgt
    27721 tcgtacgttt tacccaatcc ttcacgtaga tagtcacgtc gatagtgaca tcatcactct
    27781 catccggcgt accgggatca tccttacccg gggtataagg taacggatcg cccaagccac
    27841 gaataccttt cacatacaac tggtacacgt tattgcgtac gatacagaat tccatcacgc
    27901 ccatcagacc atcgtttccg ttatcgttat gacggatcca aaacttgtga tagcttcttc
    27961 cgcttttgta tagggaaaca ttatagtatt ggtataaatt gccgatctgc tctgagcaga
    28021 attgagatac aggggtaata ttagaaggaa gatgcgaagc ttgtctccta aaagccgcat
    28081 aagtcaattt ctgtttaaga tcctcatcaa gagttgcttt accagtcaaa atcccatcca
    28141 aatattcctt aaatgcgctt tctaatccat tttgagaaga catatcttga accgccttct
    28201 tcacagcatt gacatccgca gttatatcgt cccaaccatc cataaagcct ttcaataaat
    28261 ttttcttgtc gttttccaaa ttgaacgcac gggcggcaac gctcttcaca tctttataaa
    28321 caagacgtga cacagaacca ttactattat aatgagccgc ggaaagaaac gttttatcac
    28381 cattaggcaa attcacagac ttgatctccc cattttcata ggaactcacc ttaaagtcgt
    28441 tactcggagt aaattcagac tcgaagatta caccagtagt atagccatgt acctgcgagt
    28501 tcagatccaa cgtattttcc ttggtataaa caaccgggta atatgtccga ctatcaccac
    28561 ttacttcctg tgtatagctt aatccagaag taggcataga caccatctta tccaagttat
    28621 tcaaatcagt tgaattgctc ggattaaaat aattgacata tgaatcttta aattgatccc
    28681 aagaagaact ttccccttcc ggcaatttct tttcccggat cttcggatct aacacataat
    28741 tgtacgatcc ggcaccagtg tcattattcc tccatatcca tttctcatca cctaaatatc
    28801 gaacaggatc gttggtacca tctgccggca ataccgcatt agcaccatag ttatactgta
    28861 ccgtaggaga aacttgctta aaaagataac tctcgccctt ccactgattc actaccttat
    28921 acctcttcaa cgtgaacgta cccttattct ttacaggaga agttcccggt atattagtca
    28981 gatctaaatt cgaggagtat gccaaatcaa tacgagcggc taaacgttct acgaacaccg
    29041 ttgtccgagc cggatatgtc tcatccatat tcgcagcaga aagttcaacg atagaactgc
    29101 cgttagaagg aatagcacca cttatcatct tatgtgtaga cattacaaaa tgatggtact
    29161 ccgccatatt actagcagga gtccacaatg ccctatcgtt tgcggcaact ctatcgcgca
    29221 agtctgccaa cgtactaata ccagtcaacc ttcctcccgc attaataacg gcaaatacct
    29281 gataattgct cttatcttgt gtcagaggat tcttcatggt tactttcatc gtaacctttc
    29341 cgtcaccatg accaggctca gttccaccta aactcgcatc aataccttcc agattcgaat
    29401 aataaccttg gcctgcgatc tgtatactac taccattgtc agtatttagt aactctagct
    29461 gattgccatc ccccaaagac tcttcatctg ttggcaccaa gaatatatta acatcatata
    29521 ccataccctc cttagagccg gaaagctcac caagagaacc attaccatcc tcgccccaac
    29581 cggctccccc ctgattagga ttagaaggag tagtatctgc tttcgttagc gttccttgcg
    29641 aaaccgtaga gacgttcacc gtcatataga ccttctcgcc atcctcttcc gccccggtgt
    29701 tattttttcc gttgtcgaga tcatcggaac aaccggccgc caataaaagt gccgttgcca
    29761 tcgctacgta ccattttttc tttttcataa tattaaaatt tttgtctgtt atcttatcct
    29821 atttttactc ttgccgtttc tctgcgatct gcctcaagtt ctcctccacc tgcgaggcca
    29881 tggaaggatt gtccgacaac ttacccagca gggcctccgc ctcgtccaag cggttctcca
    29941 gcatggcgat ggccgcctcc gccaaggtac gctccgcgga attggaagtc ttcgccaaat
    30001 aacggcgggc cgattccaag cgacccgcgt cgatcgccgt aagggcggcg ttcagattcg
    30061 acaccggatc ctccggatac atacgcacgg caatctcgaa gacctcgcgg taagcgtcgc
    30121 tacccggttc catcgtctgc gccacctgaa acatctcatt tagactcaac tgcctggggt
    30181 ccgaatagat caactcacgg gcctcctcta ccgtaaacga acggatcgta taacgcaccg
    30241 cgtaatccga atggcgcaag gcgggataaa tatcacgcaa gagtacccga tacgaggccc
    30301 ccccgttcaa cgcctttagc ttcgcctcgc ggcggtcgta atccttcggc tcgtccgcac
    30361 ggatgatggc cagcaactcc tccttgtccg caagcgagga gttctccacc cgtttctcca
    30421 atccggccca gtcctccggc tcgaaatcca ccgtgaaacg ggcctgctca aagtggtaaa
    30481 ggcccttcac gtattcgatc aacgccttgg cgcggtgctc ggccagataa gtgttatgct
    30541 tataggtacc ttccggcgat gcgaaaccct tgatatatac ctccgtgatg gtagcgtaag
    30601 gatcatcctt caccgacgag acggtctcga ggatcttgcg caactccgag ggattgtcgc
    30661 gatactcggg atatatctcc gtgcggttta ccgggaagtc gaggaaggcg cttccttcct
    30721 tcacacgctc tttcacacgc tctgcctccg gcgtgacgta ggccaaaagc ggccgcaata
    30781 ccacaggctc tgcgattcgg atcgggaaaa gcggtgactt atcattactc aacgcctccc
    30841 agccgcaacc gcaaaaatcg gctaccagcg acacctccga acgctccatc cacttaacga
    30901 aaggaatgga ggcatggtaa tcgaacgtct gctccttccc attgtgacgg cgtaagacaa
    30961 actccccgtt cgccgtcgca tcacgcttgg atcgctcgta ctggatctgg cggttgcgcc
    31021 cgttcacgat cacgggaggc aaagccctta cgctatcgcc ccgctcgatc agcggcgtac
    31081 agaccaaact ccggttggcc gatagcgaca actcgtccaa cgctagtttc atatcaatta
    31141 tcaagcgatc gcccacatgc tccaccaacc gctccttcac gacgatggcg gtagccgtct
    31201 gctgcgcctg tacgggaatc gtagtaccca cacaaccggc caaacaggcg atcccaagta
    31261 tcatccatcc ttgtagattc ttcatttttc agtcctccat cgatttaaaa ttggtaaatg
    31321 agattgatcg ccgcctgcgt aggcccgaag taatgcttct tgatcccttc ttgcttgcga
    31381 ccgcaattcg cgcagggata cttgtccgac ttcaagtaca gatagcccac gcccaccgtg
    31441 gcctccaagt tccaatggcg agacagcagc cacgagtatc cataactgat accggctccc
    31501 gcgccccatc cctggtgacg ctcgccctct gtacccagcc atttgatatc ggttacatta
    31561 tataataggt acggagtatg cacgccgagg aaatggccgt taaacgtctc gcaaaaccaa
    31621 tacctcaact ccgggtgcag acgcaaatgc ttcagtgagc ggccataact cccatcatcg
    31681 ttcttgccgc tgaacggatt caagcctgcc tccaactcaa gtgtccaatg acgggcgaga
    31741 taaacttcag cccccaaatt aaacgtggca gtagcccaat aaggaatatt actcttgatc
    31801 ccaatcatgg agcctttccc ttcgaccggc accccctgcg ctctcgaaag aaacgggact
    31861 gccaacaaga atagcatgaa aatcgtcttc ttcattcttt cttattcatt atggttgtta
    31921 atcttatatc ttctcaccct tctgcccctc aagacccaac ttcctaaaat caactaacgg
    31981 caagaatggc ccgtggactt atttatggaa taaggtttag cgtttcaaaa acgttagagg
    32041 agaataagcg ttaaacaaca tcttattgtc gtttatatag tatatcaata aaccacacgg
    32101 aacgtttcag aaaaacatgt acatgttttc ctgaaaagac gtacatgttt tttggaaaac
    32161 acgtacatga aatccaataa atattatggt gtttctatac agctaccaat caatggctta
    32221 catataggcc tatccaaacg agcttattgt attatttgtt tttgatattc aggaggaatt
    32281 tgtagagtat agaaattcct cttta
//
LOCUS       DBMDTB010000035        32136 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_540_length_32136_cov_11.202060, whole genome shotgun sequence.
ACCESSION   DBMDTB010000035 DBMDTB010000000
VERSION     DBMDTB010000035.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 32136)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 32136)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32136
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_540_length_32136_cov_11.202060"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            462..1004
                     /locus_tag="ACZPB4_07575"
     CDS             462..1004
                     /locus_tag="ACZPB4_07575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011965897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0008289 - lipid binding [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin family protein"
                     /protein_id="HIR1098115.1"
                     /translation="MRFKLIGLICLIMQCNLSCTQHIINKETVQTLDLHRYMGKWFEI
                     ARFDHRFEHNLVGATVEYSFLPNGDIEVVNSGYWGNFSGSFKRAKGIAKITDPTCPSK
                     LKVCFFMRFYAEYNIMEIDEDNYSYALVGSNTSDYLWLLSRTPTLPEEAILFLLTKAK
                     ERGYNTSMLKWVKQKHENQK"
     gene            1086..1508
                     /gene="mscL"
                     /locus_tag="ACZPB4_07580"
     CDS             1086..1508
                     /gene="mscL"
                     /locus_tag="ACZPB4_07580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA];
                     GO_process: GO:0034220 - monoatomic ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="large-conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HIR1098116.1"
                     /translation="MKKILQEFKQFAMRGNVVDMAVGIIIGGAFGKIVSSIVADLIMP
                     AVGLLVGGVNFTDLKITLKHAVMEGDKVISPAVSINYGNFIQVTLDFIIIAFAVFLLV
                     KGVNALSKKKEEAPKAPVAPPADIQLLTEIRDLLKNNK"
     gene            1584..1805
                     /locus_tag="ACZPB4_07585"
     CDS             1584..1805
                     /locus_tag="ACZPB4_07585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098117.1"
                     /translation="MKNVLFGLAVGVVVGYVLRRMEDQGQFECLENELHGLTDKAKKK
                     VKDVVDTGKNQVEYVKDRVEHMVEKPKSN"
     gene            1948..2784
                     /locus_tag="ACZPB4_07590"
     CDS             1948..2784
                     /locus_tag="ACZPB4_07590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head GIN domain-containing protein"
                     /protein_id="HIR1098118.1"
                     /translation="MRTRMMALFALIAFCAMPIEAKKVKGNGDIITKEISVRDYSAIK
                     VGSTAMGYSDSWFSLFSRGGNPSYVFGYTQGESASLRITIDENLYPYINVQVKNEELS
                     ISTENGTQLSPTRFKIEGTSKKLEKIKMSGCMDFVLRSALSGDDLEIIATRGSDVKME
                     QPINVSNCIIEATSGSDIIINDLTTRIIRGRASGGSDLKLTGKAENGEYSASGGSDIK
                     AYDLILNQLECSASGGSDIYTHVTDYIKASASGGSDVHYKGSARSDTSTSGGSDIIKE
                     GN"
     gene            complement(2804..4519)
                     /locus_tag="ACZPB4_07595"
     CDS             complement(2804..4519)
                     /locus_tag="ACZPB4_07595"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1098119.1"
                     /translation="MSLKIKTKLRYGIGLLFAMIVLLGGLSVKNISDMSADTRNILAD
                     NYNSLLYSRRMLDALERIDSDPSAQADFEKNLGLQKKNITEVDENVATSHLVAQYEQL
                     AKERNEENIRRVRLALNQVMSLNMASIYRKSQVAESTSQKALFWIWGIGLSCMVVAFA
                     FLIRFPRSINTPIRMLMDGIMEIANHNYEKRLDLAKYDEFEGVAKSFNRMAERLTEYR
                     KSTLADIIQGKKYIEAIVNSITEPIIGLDRDRKILFANNEALTILNLKRENVIGKSAS
                     ELSLRNDLLRRLVRELIQPSEKKEPLKIYADNKESYFQVQYIPIRVLENGEAEVYVGD
                     VILLKNITEFKELDSAKTTFISTISHELKTPISAIMMSLKLLEDARVGAMNDEQKALA
                     ESIKESSNRLLEITSELLKMTQVEAGKLQLNPKITKPIELIEYAIKANQVQADRFNCH
                     IEVEYPEKISKLFVDSEKIAWVLTNLLSNAIHYTPENGRIIIGARQQDHSVEIYVQDF
                     GKGIDPRYHQSIFDRYFRVPGTKVQGSGLGLAISKDFVEAHGGTLSVDSAVGKGSTFV
                     IKFNV"
     gene            complement(4646..5986)
                     /locus_tag="ACZPB4_07600"
     CDS             complement(4646..5986)
                     /locus_tag="ACZPB4_07600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent transcriptional regulator"
                     /protein_id="HIR1098120.1"
                     /translation="MGKVLIIDDEKQILGLLSRIIGLEGYEVLQAATCKAGLRQMEQH
                     SPEVVLCDVFLPDGNGVDLVSDLKKLRPLSEIILLTAHGNIPDGVQAIKNGAFDYITK
                     GDDNNKIIPLVAKAMERASAAYQQQKKEATSVGRQYSFDTIVGKSPAIQAAIALAQKV
                     SATEVPVLLTGETGTGKEVFAQSIHQHSSRKGKSFVAINCSSFSRDLLESEMFGHKAG
                     AFTGALKETKGLFEEASGGTIFLDEIGEMAFDLQAKLLRILETGEFIKIGDTKPTKVD
                     VRIIAATNRDLEKEIELGHFREDLFYRLSVFQIHLPALRERVEDIPLHIKAFVSAFSS
                     KMGKNIRTISPEYIDALKKRAWKGNVRELRNAIERSLIIADGDTLTLDALPLNMQTSS
                     AASTESYSGFDLSGVEKMHIQKVLKYTKGNKTETSRLLGIGLTTLYRKIEEYGL"
     gene            complement(6045..6710)
                     /locus_tag="ACZPB4_07605"
     CDS             complement(6045..6710)
                     /locus_tag="ACZPB4_07605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HIR1098121.1"
                     /translation="MDITDMFKIPLFKNFTLKMREEFLDKLEYTVEEHPKGKTIIHQG
                     TTCNALHVLLKGKLNVDVLDVSGNIVRVETIQAPRTFATPHIFSEKNQFPATFTVDED
                     VVLLKGSKESVFTLMHSMPLFLHNFLCVSTSCNKCTMTRLKVLSFRGIRNRFIYYLFE
                     HQQKDSNVVELEHTQEQLAEYFGVTRPALSKEIGRLVDEGFISITRRKVTILNKTALT
                     CML"
     gene            complement(6770..8062)
                     /locus_tag="ACZPB4_07610"
     CDS             complement(6770..8062)
                     /locus_tag="ACZPB4_07610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate export family protein"
                     /protein_id="HIR1098122.1"
                     /translation="MKKLVVLVAGLLSVALFAQAEETQNTKENTFSMKVQIRPRAEYR
                     NGVLFPRPKDAESTGFINNRARFSLGYERDRLSIGLSAQHVGVWGQDPQIDKNGRFIL
                     NEAWAKLDFGSGFFAKLGRQSLVYDDERIMGALDWNVAGRYHDALKLGYENTNNQLHL
                     ILAFNQNDEKTIGGTYYAPGAQPYKTMQTLWYKHLFDKSFNASFLFMNLGMEGGDAEK
                     QNSDTKYLQTLGTNLIYTPSHWMVGGMFYYQFGKTKSGRDVSAFLWAVNAAYQIDPQW
                     KIGVGSDYLSGSDGADGKYKAFDPLYGTHHKFYGAMDYFYASSFVNGLNPGLWDNQVN
                     VAYKPSSKVNLSLAYHYFSITGDVYEGNDKLSKGLGSELDFQVDWVIMKDVKLSAGYS
                     TMLGTNTMKVVKGGNPSHWQDWGWLSININPTIFTTKW"
     gene            complement(8079..8873)
                     /gene="ccsA"
                     /locus_tag="ACZPB4_07615"
     CDS             complement(8079..8873)
                     /gene="ccsA"
                     /locus_tag="ACZPB4_07615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011965893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0020037 - heme binding [Evidence IEA];
                     GO_process: GO:0017004 - cytochrome complex assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c biogenesis protein CcsA"
                     /protein_id="HIR1098123.1"
                     /translation="MDWSYFIYFAAPALLCWIGGAWLAYRPSFSKGAVAWTVFGLVIF
                     SAFIVGMWISLERPPLRTMGETRLWYSFFLPVAGVITYVRWRYKWILSFSTLLAFVFI
                     CVNLFKPEIHNKTLMPALQSPWFAPHVIVYMFSYAMLGAAALIAIYLLIRARKKGIDE
                     GMMSLCDNLVYVGMAFLTIGMLFGALWAKEAWGHYWNWDPKETWAAATWLGYLIYIHY
                     RLRHHLRYSAALGLLVFSFLLLQVCWIGVNYLPSARGYSVHTYNME"
     gene            complement(8875..10065)
                     /locus_tag="ACZPB4_07620"
     CDS             complement(8875..10065)
                     /locus_tag="ACZPB4_07620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c biogenesis ResB family protein"
                     /protein_id="HIR1098124.1"
                     /translation="MWKQPWGSAEGWAICAGLLITGFGLQLITGPVQAGLFQYPVNVA
                     GGLIFLLVLCIGFVVSRKITVVQWFSGLTASITSLSALLSVVLVMGFVGPGIERITMS
                     WPFVLLFLYFLFVLGFVTLKRIVSFRWRDVPFMLNHAGLFITLLAAILGNGDLRRLRM
                     TVPLENPEWRASDEKNEMIELPLAIELRSFTIDEYPPKLMLIDNTTGKALPEKQPENL
                     LVEETPLAGNLQGWKVEVTRSLPMAACVMGQDTVNFVEFHSEGATTALYVKARNELTG
                     RQKEGWVSCGSYIFPYISLQLDDAVSMVMPEREPRRFASDVMVYTKDKQTKEACIEVN
                     KPLSIAGWKIYQLSYDETKGKWSRMSVFELVRDPWLPIVYTGILMMIAGAIGLFLSAP
                     VKKE"
     gene            complement(10068..11552)
                     /gene="nrfA"
                     /locus_tag="ACZPB4_07625"
     CDS             complement(10068..11552)
                     /gene="nrfA"
                     /locus_tag="ACZPB4_07625"
                     /EC_number="1.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-forming cytochrome c nitrite reductase"
                     /protein_id="HIR1098125.1"
                     /translation="MEKKLKSWQGWLLFGGTMVVVFVLGMIAASVNERHAEVTSVMNN
                     RKTEITGIEARNDKFEPNYPREYQTWEATADTSFKSLYNGNQAVDVLEARPEMVILWA
                     GYAFSKDYSTPRGHMHAIEDMRNTLRVGAPMTENEGPQPATCWTCKSPDVPRMMQAMG
                     VDNFYKGKWASLGKEIMNPIGCADCHEPENMNLHISRPALIEAFQRQGKDITKATQQE
                     MRSLVCAQCHVEYYFKGDGKYLTFPWDKGSTVEDMEAYYDEAGFSDYTHKLSRAPILK
                     AQHPDYEISQMGIHAQRGVSCADCHMPYKSEGGVKYSDHHIQSPLAMIDRTCQVCHRE
                     SEETLRNNVYERQNKANEMRNRLETELAKAHIEAKFAWDKGATEDQMKDVLKLIRQAQ
                     WRWDFGVASHGGAFHAPQEIQRILGNGLDKAMQARLATAKVLAKLGYTDDVPMPDFST
                     KEKAQQYIGLDMAAERTAKEKFLNTIVPQWVKEAQENNRLAKNI"
     gene            complement(11571..12161)
                     /gene="nrfH"
                     /locus_tag="ACZPB4_07630"
     CDS             complement(11571..12161)
                     /gene="nrfH"
                     /locus_tag="ACZPB4_07630"
                     /EC_number="1.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c nitrite reductase small subunit"
                     /protein_id="HIR1098126.1"
                     /translation="MKIREIIQTLFPTRTWKLAAIIAGGVLCGLGSYTLYASRAWTYL
                     SDDPATCVNCHIMGPYYATWNHSSHSRNATCNDCHVPHENAVKKWFFKGMDGMRHASV
                     FMMRGEPQVIQAIDESAEVIMNNCIRCHTQLNTEFVNTGRIDHEMAMAGEGKACWDCH
                     REVPHGGTNSLSSTPNALVPYPKSVSPDWLKDMLSK"
     gene            12263..13096
                     /locus_tag="ACZPB4_07635"
     CDS             12263..13096
                     /locus_tag="ACZPB4_07635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011965889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015288 - porin activity [Evidence IEA];
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA/MotB family protein"
                     /protein_id="HIR1098127.1"
                     /translation="MKRLLFISVSALLLCSSCVSKKKYLLAENGRLEAIGRGDVLKEE
                     LIKCKDDNDALNNRIAALIRDTTTMGRDIRNYQTMLNTNMGEQDKLNALLQQKMSELD
                     ERERTINELQDMMNAQNAKVQNLLSSVKDALLGFNSDELTVTEKNGKVYVAMSDKLLF
                     QSGSAKVDKRGKEALAKLAEVLNKQNDIDVYIEGHTDSKPINTAQFKDNWDLSVIRAT
                     SVVRILTKDYGVNPLQIQPCGRGEFMPVADNETADGRSKNRRTEIIMAPKLDKLMQML
                     Q"
     gene            complement(13152..13703)
                     /locus_tag="ACZPB4_07640"
     CDS             complement(13152..13703)
                     /locus_tag="ACZPB4_07640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MshD"
                     /protein_id="HIR1098128.1"
                     /translation="MRHLIVVCLAFMMGLNVACSRVEDLGKDDLHSEPTIEIVSGDTL
                     DIVGFTLAHELATSEGRLPYNVGDEFGYTGSYTYKSYVVRTEYTYQDDGNSIWVWEDT
                     LSSIIGFYPYLRSEVYDLADVQFHIRSCAQGGSVSVGERTDRYDTALLHIIRSANGED
                     MDVWIPCKPSELRYRCVVYHLEE"
     gene            complement(13705..14250)
                     /locus_tag="ACZPB4_07645"
     CDS             complement(13705..14250)
                     /locus_tag="ACZPB4_07645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098129.1"
                     /translation="MNKGLFLCGLFIALFLAACGDDEVKIANQMTLYSRPDTIHLGGD
                     LGMDSILVKGFTACEAYDAKWGTLPGDVAQEFDMNASYLYFSYEARVVSLEDSIYDIG
                     QNSYAEEKAGFLKDFSSQGFVISSQHMRDDKRQVIACTYLIYVEKNSDGEKIDRWLPV
                     RPEELRWRYLRVNFDQLKNIE"
     gene            complement(14404..15627)
                     /locus_tag="ACZPB4_07650"
     CDS             complement(14404..15627)
                     /locus_tag="ACZPB4_07650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar MFS transporter"
                     /protein_id="HIR1098130.1"
                     /translation="MEKQKKQSLVAAPGGKSYLVPFILITSLFLLWGFAHGLLDVLNK
                     HFQGVFTMTKAESGLVQFSTYIAYFLMALPAGAFMKRYGYRKGIIMGLLLFAIGAFGF
                     IPAAFLHSATPFLIALFVIACGLCILETAANPYSTILGPPASAAQRLNLSQSFNGLGW
                     ILGPLVGGLLIFGAPEGDSMALTKPYILVGGIVLFVALLFFFTKLPEIKLEEEEEVTA
                     IVEEKPAASLWKRRQFVRSVVAQFCYCAAQTGIFGFFINYVTEMDPGISNLRASRILA
                     FGGMALFMIGRLSGSFTMKWLAPGRLLTWYSLLSAVCMALVVASVGTLSLYALYLSFF
                     FMSIMFPTIFALGLEGMGVYTKKASSYIVMGVAGGAFSPMLMGYIGEENMALGFIVPL
                     IAFLYILYFAIKCKR"
     gene            complement(15636..15986)
                     /locus_tag="ACZPB4_07655"
     CDS             complement(15636..15986)
                     /locus_tag="ACZPB4_07655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HIR1098131.1"
                     /translation="MKRYCQTLDLKEDEQLIKEYCYWHSPEHIWPEIPEGIRAVGILN
                     MEIYRLGTRLFMIVETPDDFDWDAAFARLATMDKQAEWEDFVARYQKAAPGSSSSEKW
                     QLMECMFKLPGASK"
     gene            complement(16030..16656)
                     /locus_tag="ACZPB4_07660"
     CDS             complement(16030..16656)
                     /locus_tag="ACZPB4_07660"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016817 - hydrolase activity, acting on
                     acid anhydrides [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0009132 - nucleoside diphosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HIR1098132.1"
                     /translation="MSRSKELILLAQRIRALSQTGLVYSLSEYDTERYEELSRLSDEI
                     TALATGLKPDDVASGYRPAQEYVTPKVDIRAVVFNEKDEILLVREKMDGCWSLPGGWS
                     DVGYSPKEVAAKEVKEETGLDVLPVRLLAVMDMSKHPHPAIPYYVYKFFILCELKGGS
                     FTETFDILGKGFFRLEELPPLSLERVLPEQIQRMYAYYKHPGEDVYLD"
     gene            17031..17459
                     /locus_tag="ACZPB4_07665"
     CDS             17031..17459
                     /locus_tag="ACZPB4_07665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008148924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0009408 - response to heat [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HIR1098133.1"
                     /translation="MTPMRRSQNWLPYVFNDLFDNDWMIKANSTAPAINVIESDKDYR
                     VEVAAPGMTKNDFNIKIDENNNLVVSMEKKEEKNEDKKDGRYLRREFSYSKFQQTMVL
                     PDNVEKDKIEAKVENGVLSISIPKRTEEEAKMAEKVIEIK"
     gene            17550..18029
                     /locus_tag="ACZPB4_07670"
     CDS             17550..18029
                     /locus_tag="ACZPB4_07670"
                     /EC_number="1.16.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005788812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008199 - ferric iron binding [Evidence
                     IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA];
                     GO_process: GO:0006879 - intracellular iron ion
                     homeostasis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin"
                     /protein_id="HIR1098134.1"
                     /translation="MLSRKLSDALNEQINMEMWSSNLYLSMSVHFTQIGLDGFAHWTL
                     KQSQEELEHAYKMIDYSIKRGGQVTIGVVNSVPTAWGEPLEIFQHIYEHEVHVSGLID
                     KIVDIASEEKDKATQDFLWGFVREQVEEEATAKNIVEKLKLYGEHHAVLMDHQLGKR"
     gene            complement(18112..18891)
                     /locus_tag="ACZPB4_07675"
     CDS             complement(18112..18891)
                     /locus_tag="ACZPB4_07675"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011965884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HIR1098135.1"
                     /translation="MRQIKGVICILISIVMCWSASAANNKRYVNIVFIGNSITFGAGL
                     PKPVHDAPPVKAALFLSKCPEVASVKYSNRGQSGCTTVDYLPDTNTLFPWAVRAADKF
                     KDETWADLVFSIMLGTNDSAIEGTNGCPVTPERYYENMKTIINRLLALYPNCRIVVHR
                     PLWYSPNTYNGAKYLEEGLRRLQDYYPQIQRLVDYYASHFPGQVFLGDTKGFDYFKEN
                     HLTDFQAEKGNAGVFYLHPNEKGAVRLGELWSEAIRQALGL"
     gene            complement(18878..19771)
                     /locus_tag="ACZPB4_07680"
     CDS             complement(18878..19771)
                     /locus_tag="ACZPB4_07680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011965883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine ABC transporter
                     substrate-binding protein"
                     /protein_id="HIR1098136.1"
                     /translation="MRRFTIIIGCCMLLVTLQFIFSCVDSKDRKKISIAYANWAEGIA
                     MTNLAKVILEDQGYRVTLKNADIAPIFTSVASGKADVFMDAWLPVTHADYMEQYGDRL
                     ETLGTVYEHAKLGLVVPEYVTIRSIEDLNAHKDQFKGEIIGIDAGAGLMNSADKAVQD
                     YSLDFDLKSSSGATMVAFLKKSIDANEWIVVTGWTPHWMFSRYPLKFLEDPKEEFGDS
                     EHIEVIATKGFSEKDPYAASFFKNFKLTDEQLSELMYYMEDGTRTESRSARAWLEKHP
                     EIIKLFLPSQENQLNGSHETN"
     gene            complement(19800..20633)
                     /locus_tag="ACZPB4_07685"
     CDS             complement(19800..20633)
                     /locus_tag="ACZPB4_07685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1098137.1"
                     /translation="MINIGKYIEIAINWLTEHFARFFDVINDGVGGFIDAFQDGLTWI
                     PFYVMILGLALLAWFKAGKGVGVFTALGLLLIYGMGFWVETMQTLALVLSSTIIALMI
                     GVPLGIWTARSDRADKIIHPVLDLMQTMPAFVYLIPAVLFFGLGPVPGAFATVIFAMP
                     PVVRLTDLGIRQVPADIVEATRSFGATSSQLLYKVQLPLALPTIMTGVNQTIMLSLSM
                     VVIAAMISAGGLGEIVLRGITQMKIGLGFEGGIAVVILAIILDRITQGWAKGKVNKQK
                     K"
     gene            complement(20630..21856)
                     /locus_tag="ACZPB4_07690"
     CDS             complement(20630..21856)
                     /locus_tag="ACZPB4_07690"
                     /EC_number="7.6.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008767787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0015697 - quaternary ammonium group
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary amine ABC transporter ATP-binding
                     protein"
                     /protein_id="HIR1098138.1"
                     /translation="MTKIEIKNLSILFGPEKMRAKRMLVAGKSKQNILKETGCTVAVR
                     NANLKIEEGELFVIMGLSGSGKSTLLRCINRLNEPSLGEVFINGKNITTSSDKELLDI
                     RRKEMAMVFQHFGLLPHRTVLSNIAFGLELQGVPKKERDQKAVESVALVGLKGYENQK
                     VSELSGGMQQRVGLARAIANDPEVLLMDEAFSALDPLIRVQMQDELLKLQEKMQKTII
                     FITHDLDEAIKLGDRIAIMKDGEVVQVGTPEEILTDPANHYVSRFTENVDRGRIVTAS
                     SIMITQPVVARIRKDGPETVLRKMKEKNLYVLPVVDGNRQFLGEVRLKDVLALRKAGN
                     HDLSSIVMKEVPSVLENTTVEDMLPLLPEIRQALPVVNEANQLAGLVSTSSIIIEMTG
                     KDKEEIDQIVQNAIEL"
     gene            complement(22027..23895)
                     /locus_tag="ACZPB4_07695"
     CDS             complement(22027..23895)
                     /locus_tag="ACZPB4_07695"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing sensor histidine kinase"
                     /protein_id="HIR1098139.1"
                     /translation="MEVSEVKQRLLTDFFTYYPMGGALYDKNGALIDINKSLNEKFPF
                     TNEADFLLNNLFRTDLLTDLQKQYLRGGSVVSGSLPVPYSIIPSMNEDRDILGYTLLL
                     TGNPAVGQEAAGYDRELKELTDMSQKMAEAVPDTILLVNKQLVVERIIAYAVETCITP
                     ESINRRIDDLPGFIYPDETKRRVAAIVQSCLNKSEIMNLDLSIPGHNAPIVYFKLRLV
                     PVHDRYVIIYIRNVSELVEQEKANEALSSKLSESRMMMELALQNSKITTYSFNFSRFK
                     SCDKVHCNRCFQFYGTTNSLLKRNQFICQALPQLRHPDDSGDFFYLFNTIRTNKLDEY
                     KIDFRLKNDDNTYRIYEVIGKTHEKDENGFPNLIVGCMIDDQERLEFEEDLILAKEKA
                     EEADMLKSTFLANMTHEIRTPLNAIVGFSDLLGVEEDSELRQNYISLIKMNNDLLLSI
                     VNDVLDISRIESDMMTFTYMDVYLPSFMKDLYNSIQLRRPEGVEMTLDACPDIIFNID
                     RNRLWQICMNLLTNAVKHTKKGRIWFGYTLEAEEKMIKFYVSDTGCGIPKDELDNIFA
                     RFVQLSDFEQGVGLGLAICKGLVLKMGGNISVISEEGFGSTFIFTLPMKRPNSWKN"
     gene            24068..24700
                     /locus_tag="ACZPB4_07700"
     CDS             24068..24700
                     /locus_tag="ACZPB4_07700"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005777720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008379 - thioredoxin peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0016209 - antioxidant activity [Evidence
                     IEA];
                     GO_function: GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HIR1098140.1"
                     /translation="MKALIGKKAPEFHAPAVVNGNEIIEDFSLEQYVGKKYVVMFFYP
                     MDFTFVCPTELHAFQQKLQEFERRNVAVVGCSVDSQFSHFAWLNQDKNKGGIHGVTYP
                     LVSDFSKTISENFGVLAADYITNESGELISRGNPVAYRGLFLIDKEGLIRHYVINDLP
                     LGRNVDEALRMVDALQHFEEYGEVCPANWSKGKDAMKATNAGVSNYLSHH"
     gene            complement(24739..25215)
                     /locus_tag="ACZPB4_07705"
     CDS             complement(24739..25215)
                     /locus_tag="ACZPB4_07705"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HIR1098141.1"
                     /translation="MFREIRRKDRILDNELAIRLLEEAEYGFLAMSGINGYGYGIPIN
                     YVKEGDSIYFHCAPEGDKLECLRENPKVSFTVVGATQIVPGKFTTGYESTIAFGEMHL
                     DLPEEERRYALRLLVNKYSSAFKEIGEKYIEKSFYRTNILRLDISHISGKCKRLSQ"
     gene            25325..26617
                     /locus_tag="ACZPB4_07710"
     CDS             25325..26617
                     /locus_tag="ACZPB4_07710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M64 family metallopeptidase"
                     /protein_id="HIR1098142.1"
                     /translation="MRARITLLLFAILYSFTCLAQTNFEKHFTKKSLRIDFALSGNWD
                     FQAAAIQQLREEPVWAGPVKNLIDPFGYGGYYINVYDKAGKELIYSRGFNTLFEEWRS
                     TEQAKTETQSWTNSISIPYPKAPVIIEITARDKADMQFHLLLKQEIDPASIFIDRGKL
                     KENRITKIQYNGDSSGKVDLVFLAEGYTADEQEKFVADAKRFTEALFKTPPYDTRRED
                     FNVWAVDAVSEESGTDVSGKGIFKNTALNSGYYTFGVDRYLTTPDMKSIRDAVWNAPC
                     DAIFILVNTDAYGGGGMYNFYAMGTADNPRTPVVFVHEFGHSFAGLADEYFSSEVAYQ
                     DFYNLKYEPWEPNITTLVNFDAKWKDLLPANTPVPTPLDDAHKDKAGVFEGGGYIAKG
                     IYRPMDHCMMRDYAPFCPACSRAILQMIDYFTDKPIKH"
     gene            complement(26693..27406)
                     /locus_tag="ACZPB4_07715"
     CDS             complement(26693..27406)
                     /locus_tag="ACZPB4_07715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pirin family protein"
                     /protein_id="HIR1098143.1"
                     /translation="MRVVVDKAQSRGYANHGWLKTHHTFSFANYYNPERVHFGMLRVL
                     NDDSVAPGEGFDMHPHKNMEVISIPLKGYLRHGDSIKNSEVITPGDIQVMSAGTGIVH
                     SEFNDSGNEQLEFLQIWVFPREENTKPHYASYDVRPVTSEKNKLSLIIAPDGSAPASI
                     NQDAWFSLGNLDAGQVKEYKLHSKNNGVYLFVIDGEVEVSNTILSKRDGAGFWETESI
                     TIEVLKHAKVLLIEVPMMK"
     gene            27567..29060
                     /locus_tag="ACZPB4_07720"
     CDS             27567..29060
                     /locus_tag="ACZPB4_07720"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HIR1098144.1"
                     /translation="MAIYLNDVSRTFGEYLLIPGLTTKECIPANVSLKTPLVKFKSGE
                     KSAIELNIPFVSAIMQSVSGPKLAIELARNGGLSFIFGSQPIENQADMVRKVKKFKAG
                     FVISDSNLTPENTLADVLELVRRTEHSTIGVTDDGTPNGKLLGMVTSRDYREGKDPID
                     MKVKDFMTPFAKLIVGELGMTLKEANQIIWDHKLNTLPIIDKDQKLQYFVFRKDYDSH
                     RENPKELSGGDKKLLVGAGINTRDYKERVPALVEAGVDVLCIDSSDGYSEWQYETLHW
                     IKDTYGDKVLVGAGNVVDQDGFNYLADAGADFIKVGIGGGSICITREQKGIGRGQATA
                     LIDVAKARDEYFKRHGVYIPICSDGGLVHDYHMVLALAMGADFLMMGRYFARFDESPT
                     KKMKIGNNFVKEYWGEGSNRAKNWQRYDMGGNESLKFEEGVDSYVPYAGKLKDNLNVT
                     LGKMIATMCSCGSISIQELQQHAKITLVSSTSIVEGGAHDVILKEQN"
     gene            29131..31329
                     /locus_tag="ACZPB4_07725"
     CDS             29131..31329
                     /locus_tag="ACZPB4_07725"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004557 - alpha-galactosidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA];
                     GO_process: GO:0000272 - polysaccharide catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HIR1098145.1"
                     /translation="MKNLLLTVILLCFCLPFVKAADQKMILISTNETDLILQVAPNGR
                     LYQTYLGNKLVNESEFENLSWNIQAGTDGSVSTRGWEVYPCSGAEDYFEPAFAIQHND
                     GNMTSIFKYVSSESKKLDNNVTETIISLKDDVYPVEAKLHYVTFAKENVIKAWTEIRH
                     MEKKPVTITQYASNMLYFESPRYVLTEFSGDWAKEVQMSSQDLKFGKKIIDTKLGSRA
                     AMHAYPFFEIGLGAPASENTGDVLMGTIGWTGNYRFTFEVDNAGNLRVISGINPYASA
                     YELKPNEWFVTPEFIFTLSNQGTGKASRDIHDWARNYQIKDGKGDRLTLLNNWESTGF
                     NFNEKKLEELMKEAKHLGVDMFLLDDGWFANKYPRQNDKAGLGDWEVTHDKLPNGIPH
                     LVQTAKDAGVKFGIWIEPEMVNPKSELFEKHPNWAIHLPNRETYYYRNQLVLDLSNPK
                     VQDYVFSVVDNIMTENPDLAFFKWDCNSPITNVYSPYLKKKQNQLYIDHVRGVYNVFK
                     RVAEKYPHLLIMLCSGGGARCDYEALKYFTEFWCSDNTDPIERLYIQWGFSQFFPAKA
                     MCAHVTSWNKNTSVKFRTDVAMMCKMGFDISLKEMNDDEMKYCQEAVANYKRLKGTIL
                     DGDLYRLVSPYETNHSSVMYVDKAKSKSVLFAYDIHPRFGEKTFPVKLQGLDPNKKYK
                     VQEINLMPGQKSTLVTDGGTFSGDFLMKIGMNVFSTAHARSKVIELTEVH"
     gene            31364..>32136
                     /locus_tag="ACZPB4_07730"
     CDS             31364..>32136
                     /locus_tag="ACZPB4_07730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIR1098146.1"
                     /translation="MDIIHEITPLSEKDCFYIVDRRKTEFTYPIHCHLEYELNFIEHA
                     PGVRRVVGDSAEVIGEYELVLITGKELEHVWEQNACKSPLIHEITIQFSPNLFGNNIL
                     EKNQFNSIRKMLEKAQCGISFPMSSILKVYHLLEKLVSEEQSFYAVINFLTILYELSI
                     EEDYKVLASSSFAKITDIHSESRRIQKVQNYINERYQQDIRLNLLAELVGMAPSAFSR
                     FFKLRTGKTLSDYITDIRIGYAARMLVDTQRSIAEICYD"
BASE COUNT         9419 a         7872 c         6405 g         8440 t
ORIGIN      
        1 tccttccttt tgtaacagac ttatatactc tcgcatccct tccaccaaat ctttctcatc
       61 catatctctc tattttaaat tccaactgaa aacaaacacg caaagttaga catcttgacg
      121 attactaact ctcaaacaag catttacaat taaaacatct tcatatattt ttttcactgt
      181 aaagagtcat ttatttcata gttatgactt tttatttcat agttatgatt tggaaaaatc
      241 ataactatga aattttcaat acaaaaaaac atataaaaac gtggatctaa atctatcgtc
      301 cggaaatgcc acaactacga atttctcact tcagacagga tagaaatttc aaattaaaag
      361 ttaaagcaca gattgtcgaa aaaataaaaa tcctaaaata tgaacgtttt caaacttttt
      421 agaggctctc tatgtttatt atgagataaa aataaaaacc tatgcgattt aaactaatag
      481 gcctcatctg tcttataatg cagtgtaatt tatcttgcac tcaacacatt ataaacaaag
      541 aaaccgtcca gactttggat ttacaccgct atatggggaa atggtttgaa atagcacgct
      601 ttgatcatcg ctttgagcat aatctcgtag gggctaccgt ggaatactca tttctcccga
      661 atggagatat agaagttgtt aacagcggat attggggtaa tttttccggt tccttcaaac
      721 gagcgaaagg tatagccaaa ataacagatc ctacgtgtcc tagtaaatta aaagtgtgtt
      781 tctttatgcg gttctacgcc gagtacaaca ttatggaaat tgacgaggat aattactcat
      841 acgctctcgt aggcagtaat acctcagact atttatggct acttagtcgt acgcctacac
      901 tcccagaaga ggctattctc tttttattga ctaaggccaa agaaagagga tataacacat
      961 caatgctcaa atgggtcaaa caaaaacatg aaaatcaaaa ataatttctt caaatttcgc
     1021 tataagcatt gaaaatattc aacttatggc taattttgtt gttataatat aaaaagcgtt
     1081 gttttatgaa aaaaatatta caagagttta agcagttcgc catgcgaggt aacgtagtgg
     1141 acatggcggt aggtatcatt atcggtggtg cctttggaaa gatcgtatct tctatcgtag
     1201 cggatctgat catgccggcg gtaggtttac ttgtaggtgg cgtcaatttc acggatttaa
     1261 aaatcacctt gaagcacgct gtaatggagg gagacaaggt gatctctccg gcggtctcca
     1321 ttaactacgg aaatttcata caagtgacac tggattttat aatcattgct ttcgccgtct
     1381 ttttacttgt caaaggcgtt aatgctttaa gcaagaagaa ggaagaagcc ccgaaagctc
     1441 cggtcgctcc ccctgcggat atccaattac ttaccgagat tagggattta ctgaaaaata
     1501 acaaataaac accaacctta tcggttgact tgctgtttca taattacaaa aaataatgtt
     1561 ttaactcata aaaagtagta gttatgaaaa atgtattatt cggtttagcc gtaggtgtag
     1621 ttgttggtta cgtacttcgc aggatggaag atcaaggaca gttcgaatgt ctggagaacg
     1681 aactccacgg tcttacagat aaggcgaaga aaaaagtaaa ggacgtggta gacacgggta
     1741 aaaatcaagt cgaatacgtc aaagacagag tagaacatat ggttgaaaaa cctaaaagta
     1801 attaatctac ctccctgtta ttagggtaag aaaaagaagc tatcacaaaa aaagtcaatg
     1861 atagcttctt ttttttcatt ttagatgtaa cgttttttca actccattcg tcttataaga
     1921 aaagagtata aattaattac acttcatatg agaacaagaa tgatggcctt atttgcgttg
     1981 atcgcttttt gcgcaatgcc tatcgaggcg aagaaagtaa aaggaaatgg ggatattatc
     2041 acgaaagaaa tctccgtcag agactattca gcgataaaag tcggctcaac cgccatgggg
     2101 tatagcgaca gttggttcag cctattcagc cgtgggggaa atccgtcgta cgttttcgga
     2161 tatacgcaag gagaatcagc gtccttacga atcacgatcg acgagaactt atatccttat
     2221 ataaacgttc aagtaaaaaa cgaagaactt tcaatctcca cagagaatgg tacacaatta
     2281 agccctaccc gatttaaaat agagggcact tccaagaagc tggaaaaaat caagatgtcc
     2341 ggttgtatgg attttgtcct gagaagcgct ttatccggag atgatctgga aattatagcg
     2401 acaaggggta gcgacgtgaa aatggagcag ccaatcaacg tatccaattg cataattgag
     2461 gcgaccagcg gtagcgatat catcatcaac gatcttacta cccgaataat acgaggccgt
     2521 gccagcggag gtagcgatct caagcttacg ggaaaagcgg agaacggcga atattccgcc
     2581 tcaggtggct ccgatatcaa ggcttatgat cttatcttaa accagttgga atgttccgcc
     2641 agtggtggct ccgatattta tacacacgta accgattata tcaaggcttc ggcaagcgga
     2701 ggtagtgatg tacattacaa aggttcggca agatcggata catccacttc cggaggaagc
     2761 gatattataa aagagggtaa ttaataccct ctttttcacc ctcttataca ttgaatttta
     2821 taacaaaagt acttcctttt ccaactgcgc tatcaacaga aagagttcct ccatgagctt
     2881 ctacgaagtc tttactgata gccaacccta ggccactccc ttgtaccttc gttcccggca
     2941 cacggaaata gcgatcgaat atactttgat gatatcgggg atcaataccc ttaccgaaat
     3001 cttgcacata gatctccacg ctatgatctt gctggcgggc accgattatg atacggccat
     3061 tctccggggt ataatgaatt gcgttcgaca atagattcgt caagacccat gcgattttct
     3121 cgctatccac gaaaagcttg gaaatcttct ccgggtattc cacctctata tggcaattga
     3181 agcgatcagc ttgcacttgg ttcgccttta tcgcatactc gatcaattcg atcggtttgg
     3241 ttattttcgg attcaattgt agcttgccag cctccacctg cgtcattttc aatagctcac
     3301 tggttatttc cagtaatcga ttactacttt ccttgatact ttccgccagt gctttttgct
     3361 cgtcgttcat ggctcccaca cgggcatcct ccaacaattt caggctcatc atgatcgccg
     3421 atatcggagt tttcaattca tgggagatcg tcgagataaa agtggtctta gcggaatcca
     3481 actccttaaa ctccgtgatg ttcttcaata agatcacgtc gcccacatac acctccgcct
     3541 cgccattctc caacacacgg atcggtatat attgcacttg aaaataactt tccttattat
     3601 ctgcgtaaat tttaagcggc tcttttttct cgctcggctg gatcagttcc cgaactaacc
     3661 tgcgaagcaa atcgttccgt aaggataatt ccgaggcaga ctttccgatc acgttttccc
     3721 gcttgagatt caagatcgtc aaagcctcgt tattggcgaa aagaatctta cgatcccgat
     3781 ccaagcctat gattggctcc gtgatactat tcacgatagc ctctatatat ttctttcctt
     3841 ggataatatc cgccaacgta cttttccggt attccgtaag ccgttccgcc atccggttaa
     3901 aggatttcgc gaccccctcg aattcatcat atttagcgag atccaagcgt ttctcgtaat
     3961 tatggttagc gatctccatg ataccgtcca tcaacatacg gataggggta tttatcgaac
     4021 gggggaaacg tattaaaaaa gcgaaagcga ccaccataca agagaggcca atcccccaaa
     4081 tccaaaataa agccttttga gacgtagact ccgccacttg gcttttcctg tagatagaag
     4141 ccatattcaa actcatgact tgatttaagg cgagacgtac acgacggata ttctcctcat
     4201 tacgctcttt cgccaactgc tcgtattgag cgactagatg tgaggtggcc acattctcat
     4261 cgacctccgt gatattcttt ttctgtagcc ctaggttttt ctcgaaatct gcttgagccg
     4321 aaggatcgct atcgattcgt tccagcgcat ccagcatccg gcgtgaatag agcaaagaat
     4381 tataattatc ggccaatatg ttccttgtgt cggcagacat atcggagatg ttctttaccg
     4441 atagacctcc cagcaaaacg atcatggcaa acagcagccc gattccgtat cttagttttg
     4501 ttttaatctt cagactcata ggtgatgtat tttaagcgat tattattaag tttacgttca
     4561 gcaaagataa aatatttagc aatgtccgtt tctccttgca tatcttcaag atgctttcgg
     4621 gtatacataa atgcagaata tgagactaaa gcccatactc ctcaatcttc cgataaagag
     4681 tagtgaggcc tatacctaga aggcgggaag tttcggtttt attgcctttt gtgtatttga
     4741 gcactttttg gatatgcatt ttctctacgc cactcaggtc aaaaccgcta taagattccg
     4801 tactcgccgc agaggaggtt tgcatattca aagggagggc atccaaggtt aaggtatctc
     4861 catcggcaat aattaggcta cgctcaattg cattacgcaa ctcacgtacg ttacctttcc
     4921 aagctcgttt tttcagggca tctatatatt cgggcgaaat tgttcggata ttctttccca
     4981 tcttggagga aaaagcggaa acaaaggctt ttatatggag agggatatcc tcgacccgtt
     5041 cacgaagcgc aggaagatgg atctggaaaa cggaaagccg ataaaataga tcttcccgga
     5101 aatgtcctag ctcgatctct ttctctaagt cacgattggt agcggcaata atgcgtacat
     5161 ccactttcgt aggtttcgta tcgccgatct tgataaactc cccggtctca aggatacgga
     5221 gcaatttcgc ttgcaagtcg aaagccattt ccccgatctc atccaagaag atcgtacctc
     5281 cggaagcttc ctcaaacaag ccttttgtct ctttcaaagc accggtaaaa gcccccgctt
     5341 tatgaccgaa catctcgctt tccaataaat cccgactaaa agaggaacaa ttgatagcga
     5401 caaaagactt ccctttccgg gaactatgtt gatggatgga ttgagcaaag acctcttttc
     5461 ccgtaccggt ctcaccagtc aacagaaccg gaacctccgt agccgagact ttctgagcca
     5521 acgctatcgc cgcttggata gcgggtgatt taccgacaat cgtatcaaac gaatattgcc
     5581 tcccgacgga cgtagcttcc ttcttttgct gttgataagc ggcagaagct ctctccatcg
     5641 ctttggctac cagaggaatg atcttattat tatcatcccc tttcgtgata taatcgaagg
     5701 ctccattctt gattgcctgt acgccatccg gaatattacc atgcgcggta agtaggatga
     5761 tctcggatag agggcgaagt ttctttaagt ccgacaccaa atccacacca ttaccatccg
     5821 gcaagaacac atcgcacaat accacctctg gcgaatgttg ctccatctgc ctcagccccg
     5881 ccttacaagt agcagcctgt aagacctcgt atccctccaa accgataatg cgtgaaagta
     5941 aacctaaaat ctgcttctcg tcgtcgataa ttaaaacttt gcccatacac cggagttatt
     6001 tatttgggca caaatgtacg ctttttacct ttttcccaaa agcattaaag catacatgtt
     6061 aacgccgtct tatttaaaat cgtcaccttt ctccttgtaa tgctgataaa tccctcatcc
     6121 accaatctcc cgatttcctt cgataaagcc gggcgggtaa caccaaaata ctccgctaac
     6181 tgctcttggg tatgttctag ttccacgaca ttcgaatcct tttgctgatg ttcgaataag
     6241 taataaataa agcggttccg gatgccacga aacgaaagca ccttcaaacg agtcatcgta
     6301 catttattac agcttgtact gacacaaagg aaattatgca ggaataacgg catagaatgc
     6361 attaaggtaa atacagactc cttggaaccc ttaagcaata ccacatcctc atcgacggta
     6421 aaagtagcgg ggaactggtt tttctcggaa aagatatgag gcgtagcgaa cgtgcgtgga
     6481 gcctgtatcg tctccacgcg cacgatgtta cccgatacgt ccaaaacatc cacgttcaat
     6541 tttcccttca ataagacatg aagggcgtta caagtcgtcc cttgatgaat tatggttttt
     6601 ccttttggat gctcctctac tgtatattca agtttatcca aaaactcttc ccgcatctta
     6661 agcgtaaaat tcttaaaaag cggaatttta aacatatcgg ttatatccat cgtatcttgt
     6721 tttgaaaaaa ggtttactcc tgcaaatata cccttttcct tgagaactgt taccatttcg
     6781 tcgtgaatat agtcggatta atatttattg ataaccaacc ccaatcttgc caatgagacg
     6841 gatttccacc cttcacgacc ttcatggtat tcgttcccaa catcgtagaa tatcccgccg
     6901 ataatttcac gtctttcatg attacccaat ccacttggaa atccaattcc gaacctaaac
     6961 ctttactcaa tttatcatta ccttcgtata cgtcgcccgt gatggagaaa taatgatagg
     7021 ctaaagacag gtttaccttg gaagaaggtt tataggcgac atttacctga ttatcccata
     7081 agcccggatt caatccgttg acaaaagagg aggcgtagaa ataatccatg gcaccataaa
     7141 acttatgatg ggttccgtac agaggatcaa acgccttata tttcccgtcg gccccatccg
     7201 agccactcag ataatcacta cctacaccga tcttccattg cggatcgatt tgataagcgg
     7261 cgtttaccgc ccataaaaaa gcggaaacat cccgtccgct tttcgtcttg ccgaattgat
     7321 aatagaacat accgcctacc atccagtggc taggcgtata gatcaggttc gttcccaacg
     7381 tttgcaggta ttttgtatcc gagttttgtt tctcggcatc accgccttcc atccctaagt
     7441 tcataaacaa gaaggatgcg ttaaaactct tgtcgaagag atgcttatac caaagggttt
     7501 gcattgtttt atagggttgc gcgcccggag cgtaatacgt tcctccgatc gttttctcat
     7561 cattctggtt gaacgcaaga attaaatgca gttggttatt cgtgttctca tagcccagtt
     7621 tcaaagcgtc gtgataacga ccggccacgt tccaatccaa cgcacccatg atacgctcgt
     7681 catcgtatac caacgactgg cgacctaact tagcgaagaa acccgatccg aaatccagtt
     7741 tcgcccacgc ctcattcaag ataaaacgac cattcttatc gatttgagga tcctgccccc
     7801 atacgccaac atgttgcgcg gacaaaccga tagacaaacg atcccgctca taccccaaag
     7861 aaaagcgggc acggttattg ataaacccgg tggactcggc atctttaggc cgggggaata
     7921 agaccccgtt ccggtactcg gctctcggac gtatctgcac tttcatcgaa aacgtattct
     7981 ctttcgtatt ttgtgtttct tccgcttgcg cgaaaagggc cacagagagc aagcccgcta
     8041 ctaaaacaac tagttttttc atatacctct gattttaatt attccatatt ataagtatgt
     8101 acactatatc ctcgtgcgga gggtagataa ttcacgccaa tccaacacac ctgtagcaaa
     8161 agaaaagaga aaaccaaaag ccccaacgcc gccgaataac gcaagtgatg acgaaggcga
     8221 taatggatat aaatcaagta ccccaaccaa gtggcagccg cccatgtctc cttcgggtcc
     8281 caattccaat aatgccccca cgcctccttg gcccataaag cgccgaacag catcccaatc
     8341 gtgaggaagg ccataccgac atataccaag ttatcgcata aactcatcat cccctcgtca
     8401 atccccttct tcctcgcacg gatcagcagg taaatggcga taagggcagc ggcgcccagc
     8461 atggcgtaag agaacatata gactatcacg tgcggagcga accacgggct ttgcaaagcg
     8521 ggcatcaagg tcttgttatg tatctccggc ttaaacagat tgacacagat aaagacaaag
     8581 gccaacaatg tactaaagga aagtatccat ttataccgcc aacggacata agtgatcacg
     8641 cccgccaccg gcaagaagaa agaataccat aaacgagtct cgcccatcgt gcgcaagggc
     8701 ggcctctcca acgagatcca catccctacg ataaaagcgg aaaatataac caagccaaac
     8761 acggtccaag cgacagcccc cttggaaaaa gaaggacgat aagccaacca tgccccacct
     8821 atccagcaaa gtaacgccgg agcggcgaaa taaataaagt aactccaatc catactattc
     8881 tttttttacg ggagcggaca ggaataatcc gatcgccccg gctatcatca ttaagatccc
     8941 tgtataaacg atcggcaacc atggatctct taccaactca aatacactca tccggctcca
     9001 tttacctttc gtctcgtcgt aactcaactg gtagattttc catccggcga tagagagcgg
     9061 cttattcacc tcgatacacg cctccttggt ctgtttatct ttcgtataga ccataacgtc
     9121 cgaggcaaag cgtctcggtt cccgttccgg catcaccatg ctaaccgcat catccagctg
     9181 gagcgatata tatgggaaga tatagctgcc acaactcacc cagccttcct tctgccgtcc
     9241 ggtaagttcg ttacgtgctt ttacgtataa agcggtggtc gccccctcgg agtgaaattc
     9301 cacgaagttt accgtatcct gccccatcac gcaagctgcc atcggtagtg aacgggtaac
     9361 ctcaaccttc cagccttgca ggttcccggc caagggagtt tcctctacca atagattctc
     9421 gggttgcttt tcgggaagcg cttttccggt cgtattgtcg atcagcatta acttaggagg
     9481 atattcatcg atcgtaaacg aacgaagctc gatggcgagc ggtagctcta tcatctcatt
     9541 cttctcgtcc gaagccctcc actcgggatt ctccaacgga accgtcatcc gtaaacggcg
     9601 taaatccccg tttcccaaga tcgccgccag cagcgtgata aataagccgg catggttcag
     9661 cataaacgga acatcccgcc agcgaaacga tacgatacgc ttcaatgtga caaagcccaa
     9721 gacaaacaag aaatagagaa acagcaggac aaaaggccac gacatcgtaa tccgctcgat
     9781 acccggaccc acaaatccca taaccaacac aactgacaaa agagccgaca aagaggtaat
     9841 gctcgccgtt aacccggaaa accactggac aaccgtgatt ttccggctaa caacaaaccc
     9901 tatacataga accagcagaa aaatcaatcc tccggccaca ttcaccggat attggaacaa
     9961 ccctgcctga accgggccag tgatcagttg caagccaaat cccgtaatca gtaaaccggc
    10021 acagatggcc cagccttcag cagatcccca aggttgtttc cacataatca aatgttcttc
    10081 gctaaacgat tattttcttg cgcctctttc acccattgag gaacgatcgt attcaggaat
    10141 ttttccttgg cggtacgttc agcggccata tccaaaccga tatattgctg agccttttct
    10201 ttcgtagaga agtccggcat cggaacatca tccgtataac ctaatttcgc taacactttc
    10261 gcagtagcca gacgagcctg catcgcctta tccaatccat tgcctaatat cctttgaatc
    10321 tcttgcggag cgtggaacgc accaccatga gaagccacgc cgaaatccca acgccattgt
    10381 gcctgacgga tcagtttcaa tacatctttc atctgatcct cggtagcccc cttatcccac
    10441 gcgaacttcg cctcgatatg cgctttcgcc aactcggtct ccaaacggtt acgcatctcg
    10501 ttcgccttat tctgacgctc gtacacatta ttgcgtaagg tctcctcgct ctcacggtgg
    10561 caaacctgac acgtacggtc gatcatagcc aacgggcttt ggatatggtg gtcactatat
    10621 ttcacgcccc cctcgctctt atacggcata tggcaatcgg cgcaagatac accccgctgc
    10681 gcatggatac ccatttggga gatctcataa tccggatgct gtgcctttaa aataggagca
    10741 cggcttagct tatgcgtata atcggagaaa ccggcctcat cataataagc ctccatatcc
    10801 tcaaccgtag aacctttatc ccaagggaaa gtcaagtatt tgccatcgcc cttgaaataa
    10861 tattccacgt ggcattgcgc gcaaaccaag gaacgcatct cttgctgggt cgctttcgtg
    10921 atgtccttgc cttgacgctg gaaagcctcg atcaaagccg ggcgactgat atgcaggttc
    10981 atattctccg gctcatggca atcggcgcaa ccgatcggat tcataatctc tttacccaga
    11041 gaagcccatt tgcccttata gaaattatcc acgcccatcg cttgcatcat gcggggaaca
    11101 tccgggcttt tgcaagtcca gcaagtagcc ggttgcggcc cctcgttctc tgtcatcgga
    11161 gcgcccacac gcaacgtgtt acgcatatcc tcgatcgcat gcatatgccc tctcggggta
    11221 gaataatcct tagagaaagc gtaaccggcc caaaggatca ccatttccgg acgagcctcc
    11281 agcacatcga ccgcctgatt cccgttgtat aaactcttga aactcgtatc cgccgtagcc
    11341 tcccaagtct ggtactcacg tggataattc ggttcgaact tatcattgcg agcctcgatt
    11401 cctgtgatct ccgtcttcct attattcatt acgctagtga cctccgcatg tctctcgttc
    11461 acggaagcag cgatcatacc caaaacaaaa acaacgacca tggttcctcc aaacagcaac
    11521 caaccttgcc atgattttaa tttcttttcc ataactatac tgatttatta ttatttactt
    11581 agcatatctt tcaaccagtc cggcgatacg gacttcggat aaggcaccaa cgcgttcggt
    11641 gtggaagaca ggctgttcgt acccccgtgc ggcacctcgc gatggcaatc ccagcaggct
    11701 ttcccttctc ccgccatagc catctcatga tcgatccttc cggtattcac gaattccgta
    11761 ttcaactgcg tatggcaacg gatacagtta ttcatgatta cctccgcgct ctcgtcgatc
    11821 gcctgtatca cttgcggttc ccctcgcatc atgaataccg aggcgtggcg cattccgtcc
    11881 atacccttga agaaccactt cttcacggcg ttctcgtgcg gcacatggca atcgttgcaa
    11941 gtggcgttac ggctgtgcga gctatgattc catgtagcgt aataagggcc catgatgtgg
    12001 caattcacgc aagtagccgg gtcatcggac aaataggtcc acgcccggga agcatataag
    12061 gtataagacc ccagcccgca aaggacacct ccggctatga tagcggctag tttccaagtt
    12121 cttgtcggga acagcgtttg tattatttct cttattttca taccgctgat tctttaatat
    12181 tggtttatga gacacaaata tcctaaactt gcgtgtggga aattgtaata aatattacat
    12241 tgcacgaaat tttatgcgta aaatgaaaag attgttattt atctcggtct ccgcactcct
    12301 tttatgctct tcgtgcgtga gtaaaaagaa atacctcctt gccgagaacg gccgcttgga
    12361 ggcgatcgga cgtggcgacg tcttgaagga ggaattgatt aaatgtaagg acgataacga
    12421 cgcactcaac aaccggatcg ccgccttgat aagggatacg accacaatgg ggcgtgatat
    12481 ccgtaattac cagaccatgt tgaataccaa tatgggtgag caggacaagc tgaatgcctt
    12541 gttacagcaa aagatgagtg agctggacga gcgtgagcgt accatcaacg agctacagga
    12601 tatgatgaac gcgcagaacg cgaaggtaca gaatctgttg agtagcgtga aagacgcttt
    12661 gctgggtttc aacagcgacg agctgaccgt aaccgagaag aatggtaaag tatatgtagc
    12721 catgtcggat aagcttctgt tccaatcggg tagcgcaaag gtcgataaac gaggcaagga
    12781 agcgttggct aagttggccg aggtgttgaa taagcaaaac gatatagacg tttatataga
    12841 gggccatacg gacagcaagc cgatcaatac cgcccaattc aaggataatt gggatctaag
    12901 cgtgatccgt gcgacttccg tagtgcgtat ccttaccaag gactatgggg tgaatccgct
    12961 acagatacaa ccttgtggtc gtggggagtt tatgccggtc gctgataacg agaccgccga
    13021 tgggcgtagc aagaaccgcc gtacggagat catcatggct ccgaagttgg ataagttgat
    13081 gcagatgttg cagtgataat gatatggtca agctccgggt attatctact gccggagctt
    13141 ggctaaaacg ttcactcttc caaatgatag acaacacacc gatacctcaa ttccgatggt
    13201 ttacaaggaa tccatacatc catatcctct ccattcgcgg aacgaatgat atggaggaga
    13261 gccgtatcat acctatccgt cctttccccg acagagaccg atcccccttg agcgcacgac
    13321 cggatatgga actgaacatc cgcaagatca tatacctcag atctaagata aggataaaaa
    13381 cctattattg aactcaatgt atcctcccaa acccaaatac tatttccatc atcctgatac
    13441 gtatattccg tccttaccac ataggactta taggtgtaag aacccgtata accaaactca
    13501 tcccctacgt tataaggcaa acgcccttca ctagtagcca gctcatgcgc aagagtgaac
    13561 cctacaatat ccaaggtatc accacttacg atctctatcg tcggttcaga atgcaaatca
    13621 tccttaccaa gatcttccac ccgtgagcaa gccacattaa ggcccatcat aaaagctaaa
    13681 catacaacga ttaaatgtct catatcattc tatatttttt aattgatcaa agtttacacg
    13741 aagataacgc catcgcaact cctccggccg tacaggaagc cagcgatcga tcttctctcc
    13801 atctgagttc ttctctacat atattaaata ggtacatgct atcacttgcc tcttatcatc
    13861 tcgcatatgc tgtgaactga taacgaagcc ttgcgaacta aaatccttca aaaaacccgc
    13921 tttctcttcc gcatacgagt tctgccctat atcataaata ctatcctcta aagaaaccac
    13981 ccttgcctca tacgagaaat agagataaga ggcattcata tcaaactctt gcgcaacatc
    14041 cccgggcaat gttccccatt tcgcatcata cgcctcacaa gccgtgaagc ccttcaccaa
    14101 tatggagtcc atccctaagt caccccccag atgaatcgta tccggccttg aatataaagt
    14161 catctgatta gcgattttaa cctcatcatc cccacaagca gccagaaata gagctataaa
    14221 tagcccacac aaaaacaaac ctttattcat atccactctc ttttatttta tttaaaatga
    14281 aaacgatata gataagcaga tattgcttga gcgtaacatt tatcccatga aacccaagcc
    14341 ttcatacaca agccatgctg gtttattatc cggattccat aagtaaaaaa cagcattcca
    14401 aatttaccgc ttgcatttga tagcgaaata caagatatac aagaaagcga tcaacgggac
    14461 gatgaagccc agcgccatat tctcctcgcc gatatatccc atcagcatcg gactgaaagc
    14521 gccgccggca actcccatca cgatataaga agaggctttc ttggtataaa cgcccatacc
    14581 ttccagcccc aacgcgaaaa tcgtagggaa catgatggac atgaagaaaa aggataaata
    14641 aagagcgtat agtgaaagcg tacctacgga agccaccacc aaagccatac aaacggcact
    14701 caacaaagaa taccaagtca gcaagcggcc cggagccaac cacttcatcg taaaactacc
    14761 gctcaaacgc ccgatcataa acaaggccat tccaccgaat gccaaaatac gagacgctcg
    14821 caaattactg atacccgggt ccatctccgt cacgtaatta ataaagaacc cgaagattcc
    14881 cgtctgcgcg gcgcaataac agaattgggc gaccacggaa cgcacaaact gcctacgttt
    14941 ccatagggag gcagcgggtt tctcctcgac aatagcggtc acctcctcct cttcttccag
    15001 cttaatctcc ggcaacttcg tgaaaaagaa aagcaacgct acgaacaaga cgataccacc
    15061 taccaagata taaggtttag tcaacgccat cgaatctccc tccggtgccc cgaatatcaa
    15121 caaaccacct accaatggcc ccaatatcca acctaatcca ttaaaagact gggataagtt
    15181 cagccgttgg gcggcggaag caggcggccc caatatcgta gaataaggat tcgccgccgt
    15241 ctccaagata caaagcccgc aagcgatcac aaacaaggcg atcaagaaag gtgtagccga
    15301 atgcaaaaaa gccgccggga taaacccgaa agctccgata gcgaacaata gcaaacccat
    15361 gataatccct ttcctatatc cgtaacgttt catgaacgct cccgccggca acgccatcaa
    15421 gaaataagcg atatacgtag agaattgcac caagccgctc tctgccttgg tcatcgtgaa
    15481 gactccttgg aaatgcttgt tcagcacatc caagagtccg tgggcgaatc cccaaagcaa
    15541 gaacaaactc gtgatcaaga taaacgggac caaataagat ttccctcccg gggcggccac
    15601 cagcgattgt ttcttttgtt tttccatcct tccgtctatt tactcgcgcc cggcaattta
    15661 aacatacatt ccattaactg ccatttctcc gacgaggagc ttcccggagc ggctttctga
    15721 tacctcgcca cgaagtcctc ccattccgct tgcttatcca tcgtcgccaa acgggcgaac
    15781 gccgcatccc aatcaaaatc atcgggcgtc tccacgatca tgaacaaccg ggttcccaaa
    15841 cggtaaatct ccatattcaa gatccctacc gcacggattc cttccggtat ctccggccag
    15901 atatgttccg gcgaatgcca atagcaatac tcttttatca actgctcatc ctctttcaga
    15961 tccaaggtct gacaatatct tttcataaca ttgtttttaa aatgaagtcg cgaaggtaca
    16021 aaagtatcct taatccagat aaacatcttc gcccggatgc ttataatagg catacatccg
    16081 ttggatctgc tccggcagca cacgctccaa ggacaacggg ggcaactcct ccaatcgaaa
    16141 gaaacctttc cccaagatat cgaaagtctc ggtaaacgat ccgcccttta actcgcaaag
    16201 gataaaaaac ttatatacat aataaggtat agcgggatgc ggatgcttgc tcatatccat
    16261 cacggccagc aagcggaccg gaagcacatc caagcccgtc tcctctttca cctctttcgc
    16321 cgctacctct ttcggggaat accccacatc gctccatccg ccgggcaacg accaacatcc
    16381 gtccattttc tcacggacca gcaaaatctc gtctttctcg ttaaagacaa ccgcacggat
    16441 atcgactttc ggggttacat actcttgggc cgggcggtaa ccactcgcta catcatcggg
    16501 cttcaatccg gtagccagag ccgttatttc atcacttagg cggctcaact cttcataacg
    16561 ttccgtatcg tactcgctta atgaataaac caaccccgtc tgggacaagg cccggatacg
    16621 ttgggccaat aaaatcaatt ccttacttct agacataata gctttactgt tttagataac
    16681 atgatcccat atgattcatg aatagaacgt ctaaagataa aagttattat ccaacccgtc
    16741 attctatcgt gccaaaataa cgtatattat gccaatatta cagattcccg tttcattgta
    16801 tcttattcca gtttctaaaa gatattattc cctgcacccg catcccccga aacataagtt
    16861 ccccatgcgt ggattaaacc ttattcaatc tctttcatcc gagttaacac acacattatc
    16921 agattggcat accatttgaa gtatctatag cgaattcgag attaaaaagg acgagttcag
    16981 aaataagaat agtaaataga atatttaact aataattgga ggactgtatt atgacaccga
    17041 tgagaagaag tcaaaattgg ttaccgtatg tattcaatga tttatttgac aacgactgga
    17101 tgataaaagc aaactctaca gctccagcca tcaacgtgat agaatccgat aaggattatc
    17161 gagttgaggt agccgctccc ggtatgacga agaacgattt caacatcaag atcgatgaga
    17221 acaacaactt ggtcgtatct atggagaaaa aagaagaaaa gaatgaggat aagaaagacg
    17281 gacgctatct gagacgcgaa ttctcttata gcaagttcca acaaaccatg gttttgcctg
    17341 acaatgtaga gaaagacaag attgaggcga aggttgagaa cggcgtcttg agtatcagca
    17401 taccgaaaag aactgaggaa gaggctaaaa tggccgagaa agtaatcgag atcaaataac
    17461 ctcgatacac tttccttcgt aaaaactcaa caaaaccgat aatggcttgt tctatttata
    17521 aacaacataa aatagaataa gccattatga ttttaagcag aaaattatca gatgctctaa
    17581 acgagcaaat caacatggag atgtggtcat ccaacctata tttatccatg tcggtacatt
    17641 tcactcagat agggctggat ggtttcgcgc attggacgct aaaacaatcg caagaggaac
    17701 ttgaacatgc ctataaaatg atcgattact caatcaagcg tggcggacaa gtgacgatcg
    17761 gagtagttaa ttccgttcct acggcatggg gagagccgtt ggagattttc cagcatatct
    17821 acgagcatga ggtgcatgta tccggattga tcgacaagat tgtcgatatc gcttccgaag
    17881 agaaagacaa ggcgacacaa gatttcctat ggggtttcgt ccgggaacag gtagaggaag
    17941 aggctacagc gaaaaatatt gtcgagaaac ttaaattata cggagaacat catgccgtat
    18001 taatggatca tcaattagga aaaagataaa cgaatacttg cttgtcatac ctataaatgg
    18061 acctaaaaag ccatgtcgtc ttcttgggat ggcatggctt ttttatagag gtcaaagccc
    18121 taaagcctga cgaatcgcct cactccacaa ttcgcctaac cggaccgctc ctttctcatt
    18181 cggatgaaga tagaacactc cggcgttgcc cttctccgct tggaaatccg ttaaatggtt
    18241 ttccttaaaa taatcaaatc ctttcgtatc tcccagaaag acttgtccgg gaaaatgaga
    18301 cgcataataa tcgactaatc gttgtatttg cggataataa tcttggagcc ttcgcaagcc
    18361 ttcttccaaa tatttagctc cattatacgt attcgggcta taccatagag gacgatgtac
    18421 cacaatacgg caattcgggt ataaagctaa taagcgattg ataattgtct tcatgttctc
    18481 ataataccgc tcgggcgtta ccgggcagcc gttcgtgcct tctatcgcgc tatcgttcgt
    18541 ccccagcata atagagaaca ccaaatccgc ccaagtctca tccttaaatt tatcggcagc
    18601 acgtacggcc cacgggaaga gcgtattcgt atccggcaaa taatcaacgg tagtacagcc
    18661 gctctgtcct ctattggaat acttgaccga agccacttcc gggcacttgc ttaaaaacaa
    18721 cgcagccttt acaggaggcg catcatggac aggcttcggt aacccggcgc caaacgtgat
    18781 actattcccg ataaatacga tattcacata acgtttattg tttgcggctg aagcagacca
    18841 acacataacg atacttatta aaatacatat gactccctta atttgtctca tggctcccat
    18901 tcaattgatt ctcctgcgaa ggtaagaata atttgattat ctcgggatgt ttttcaagcc
    18961 aagcacgggc tgatcgcgat tccgtacgtg tcccgtcttc catataatac atcaattcgc
    19021 tcagttgttc atcggttaac ttaaagttct tgaaaaaaga ggctgcatat ggatctttct
    19081 cagagaatcc tttcgtagcg ataacctcga tatgctccga gtctccaaat tcctctttcg
    19141 ggtcttccaa gaattttaac ggataacgtg agaacatcca atgaggggtc catccggtaa
    19201 ccacgatcca ttcgttcgca tcaatcgatt tcttcaagaa agcaaccatc gtagccccac
    19261 tggaagattt caaatcaaaa tccaaagaat aatcttgaac cgccttatcc gccgagttca
    19321 tcaaaccggc gccggcatcg atccctataa tctcaccttt aaattgatct ttatgggcat
    19381 tcaaatcctc gatggaacga atggtaacgt actccggaac taccaagccc aatttcgcat
    19441 gctcataaac cgttccgagt gtctcaagcc ggtccccgta ttgttccata taatccgcat
    19501 gggtcaccgg taaccatgca tccatgaaca catccgcttt tcccgaagcg acagaagtaa
    19561 agatcggggc gatatccgca ttttttaatg ttacccgata tccttgatcc tctaatatca
    19621 ctttggctaa gttggtcata gcgatgccct ccgcccaatt agcgtacgct atcgatattt
    19681 tctttcgatc cttgctatcc acacaactga aaataaattg caaggtcacc aaaagcatac
    19741 agcatccaat aataatcgta aatcgtctca tatatctatt tctttctttt ctatgtttct
    19801 tatttctttt gtttattcac tttacctttc gcccagccct gcgtaatacg atccaagata
    19861 atagccaaga taacgaccgc tatacctcct tcgaaaccta aacctatttt catttgggta
    19921 attcctcgca agacaatctc acccaatcct cctgccgaga tcatggccgc tatcactacc
    19981 atagaaagtg aaagcatgat cgtttgattc actcccgtca tgatcgttgg caaagccaat
    20041 ggcaattgca ccttataaag caactgagag gaagtagcgc caaatgagcg ggtagcctcc
    20101 acaatatcgg ccgggacttg acggattccc agatcggtca accgcacaac cgggggcatg
    20161 gcgaaaatca ccgttgcgaa agcgccgggt accggaccta aaccaaaaaa caaaacggct
    20221 ggtatcaagt agacgaaagc cggcatcgtt tgcatcaaat ccaagaccgg atggatgatc
    20281 ttatccgccc gatcactgcg tgcggtccaa attcctaacg gaactccgat catcaaggcg
    20341 ataatggtag aagacagtac caaggccaaa gtctgcatcg tttccaccca gaaacccatt
    20401 ccgtaaatta acaatagacc caatgccgtg aacacgccga ctccttttcc tgccttgaac
    20461 caagccaaca atgccaagcc caaaatcatc acataaaacg gaatccaagt cagcccatct
    20521 tgaaaagcat cgataaatcc tccgacccca tcatttatca catcaaaaaa acgagcgaaa
    20581 tgctcagtca gccaattaat ggcaatctct atatattttc ctatatttat cataattcta
    20641 tcgcgttttg aacaatttga tctatttcct ctttatcctt ccccgtcatc tcgattataa
    20701 tcgatgaagt agaaaccaag ccagccaatt gattggcctc attaacgacc ggtaaggcct
    20761 gccggatctc cggtaacaaa ggaagcatat cctcaaccgt cgtgttttcc agaaccgaag
    20821 gaacctcttt catcacaatc gatgaaagat catgattccc cgctttccga agagccaaga
    20881 catctttcaa acgaacctcg cccagaaatt gcctatttcc atccacgacc ggcaatacat
    20941 ataagttttt ctctttcatt ttcctcaaca cggtctccgg gccatcttta cggatacgag
    21001 cgacaaccgg ctgggttatc attatcgatg aggctgtaac gatacgtcca cgatctacat
    21061 tttccgtaaa tctagagaca taatgattgg ccggatctgt caagatctcc tcaggggtac
    21121 ctacttgcac gacctccccg tctttcataa tggcgatacg atcccccaac ttaatcgcct
    21181 cgtcaagatc atgcgtaata aagatgatcg ttttttgcat cttctcttgt agtttcaata
    21241 gctcatcctg catctgtaca cggatcaatg ggtctaaggc agaaaaagcc tcatccatca
    21301 agagcacctc gggatcattt gcgatcgcac gggccaatcc gacacgttgc tgcatacctc
    21361 cagacaactc gctaaccttc tggttctcgt atccttttaa ccctactagg gctacacttt
    21421 ccacagcttt ctggtctctt tcttttttag gaaccccttg taactccaag ccaaaagcga
    21481 tattactcaa taccgtgcga tggggcagca atccaaaatg ctggaaaacc atagccattt
    21541 ccttacgccg tatatccaat aattctttat ccgaggaagt cgttatgttt tttccgttga
    21601 taaagacttc tcccaaagag ggctcgttca atcggttaat acaacgtaac agcgtagatt
    21661 ttccacttcc ggaaagtccc attatcacaa ataactcccc ttcctcaatc tttaggttcg
    21721 cattacgtac agctaccgtg caacccgttt ctttcaaaat gttttgttta ctttttcccg
    21781 ctactagcat tcttttcgca cgcattttct ccgggccgaa aagaatagat aaattcttta
    21841 tttctatttt cgtcatataa aatccttgat tacaggtatg atacaaaaag attaggccat
    21901 aagtccagaa tttcttatgg caaaacataa accaaaagca tgtataagtt aatgcttatt
    21961 atggaaattg actacaacct aaatcatctc ttatatagac aaccgaattt caaagagtat
    22021 tgttcactag tttttccaac tattgggtct tttcataggt aaagtgaaaa taaatgtaga
    22081 accaaatcct tcttcggaaa tcactgaaat attaccgccc atttttaata ccagaccttt
    22141 acaaattgct aatcccaatc cgactccttg ctcaaaatcg cttaattgca cgaatcgggc
    22201 aaagatatta tccaattcat ccttgggaat gccacaacct gtatccgaaa cataaaactt
    22261 aatcattttc tcctcagcct caagcgtata accaaaccaa atacgacctt ttttagtatg
    22321 cttaaccgca ttcgtcaata aattcatgca gatttgccat aatcgatttc gatctatatt
    22381 aaatatgata tcgggacatg catccaaggt catttccacc ccttccggtc tacgtaattg
    22441 tatggagtta tatagatctt tcataaagga aggtaaataa acatccatat aagtaaacgt
    22501 catcatatca gactcgattc tggaaatatc caaaacatca tttactatac ttaaaagtaa
    22561 atcattgttc atcttgatta aactaatata attttggcgc aattccgaat cctcctccac
    22621 tcctaacaaa tcagagaaac cgacaatagc gttcaacggt gtacggatct catgggtcat
    22681 attcgctaag aaagtcgact taagcatatc cgcctcctcc gctttttcct tggctaagat
    22741 caagtcttcc tcaaactcca atcgttcttg atcatcgatc atacagccaa caatcaaatt
    22801 cgggaaacca ttttcatcct tttcatgcgt cttaccgatc acctcataga tccgataggt
    22861 gttatcatcg ttctttagac gaaaatctat tttatattca tccaatttat tcgtacggat
    22921 cgtattgaat agatagaaaa agtcgccaga atcgtccggg tgacgaagtt gcggcaaagc
    22981 ctgacaaatg aactgattac gtttcaataa actattggtc gtgccataaa actggaaaca
    23041 acggttacaa tgtactttat cgcaagactt aaaccggctg aaattaaaag aataagtcgt
    23101 aatcttgcta ttctgcaaag caagctccat catcatccgg ctttcggaca acttactgct
    23161 taacgcctca ttcgctttct cctgctcaac gagctccgat acattccgta tataaataat
    23221 cacataccgg tcatgtaccg gtaccaaccg tagtttaaaa taaacgatcg gagcgttatg
    23281 tcccggaatc gataaatcta aattcatgat ctccgactta ttcaagcaac tttgcacgat
    23341 cgcggccaca cgacgcttag tctcatccgg ataaatgaaa cccggaagat catcgatacg
    23401 ccgattgatc gactccggcg ttatacaagt ctccacagca taagcgataa tcctctctac
    23461 aaccagttgc ttgtttacca aaaggatcgt atcaggaacc gcttccgcca tcttttgcga
    23521 catgtccgtc aattccttca attcccggtc ataaccggct gcctcctgcc cgaccgccgg
    23581 attacccgtt aataataagg tatacccaag aatatctcta tcctcattca ttgaggggat
    23641 gatggagtac ggtacaggca aagaaccgga aaccacgctt cccccacgca gatattgttt
    23701 ttgaagatcg gtcaacaaat ctgtacgaaa aagattattt aataagaagt ccgcttcatt
    23761 cgtaaaagga aatttctcgt ttaaggactt atttatatca attagtgcac cgtttttatc
    23821 atacagagca cctcccatgg gataatatgt aaaaaaatct gtcagcaaac gctgttttac
    23881 ctcggaaacc tccatatact ttctttatta acatcaataa gttacaaaga aataaaatct
    23941 ttgaaaatca gagaaatttt aaagcataaa ctttaggtct atttcacaag aaaatcagtc
    24001 tctttactaa aaagcaacaa caaaccttca cttacgcttg ttacttaaca aacaaattaa
    24061 ttataatatg aaagcattaa taggtaaaaa ggcaccggaa ttccacgctc cggcagtagt
    24121 gaatggcaat gagatcatcg aggatttctc tttggaacaa tatgtaggca agaagtatgt
    24181 agtcatgttt ttctatccga tggactttac attcgtttgc ccgacagaat tacatgcctt
    24241 ccaacaaaag ttacaggaat tcgaaagacg taacgtagcg gtggttggtt gctccgtcga
    24301 ttctcaattt tctcatttcg catggttaaa ccaagataag aataaaggag gtatccatgg
    24361 ggtgacttat ccactcgtat ccgatttttc caaaaccatc tctgaaaact ttggcgtatt
    24421 ggccgctgat tatattacga acgaaagtgg agaacttatc tccagaggaa atccggtcgc
    24481 ttaccggggt ctgttcctga ttgacaaaga gggcttgatc cgtcattatg taatcaacga
    24541 tttaccatta ggccgtaacg tagacgaggc tctccgtatg gtcgacgcct tacagcactt
    24601 cgaagaatat ggcgaggttt gcccggcaaa ttggtccaaa ggaaaagacg ccatgaaagc
    24661 gacaaacgca ggagtctcta attatttaag ccatcattga tatattgcaa gaaagggggc
    24721 taggccccct tttttatact attgagacaa tcgtttacac tttcccgaga tatgcgagat
    24781 atctagacgt aagatattag tccggtaaaa agatttctca atatactttt cgccgatctc
    24841 cttaaacgcc gatgaatatt tattcacgag tagccgcaag gcataccgac gctcttcttc
    24901 cggcaaatcc aaatgcatct ctccaaaagc gatagtgctc tcgtaacctg tcgtgaattt
    24961 tcccggaacg atttgtgtag cgccaactac cgtgaaactc actttcgggt tttctcgtag
    25021 acattccagc ttatcccctt ccggagcgca atggaaataa atagaatccc cttcctttac
    25081 ataattgatc gggattccat acccataccc atttatcccc gacatggcca aaaaaccata
    25141 ttccgcctcc tccaataaac gaattgccaa ctcattatcc aaaatccggt cttttcgtct
    25201 gatctctcta aacataggtc taatttattt ataaacgagt ataatacact aatcgtggca
    25261 aatctaaaaa aaaataatat acatttgcgt cataaagttg acacatgata aatattatag
    25321 atctatgaga gcaagaataa ccttattatt attcgccatt ctttacagtt tcacttgtct
    25381 ggcacaaact aattttgaaa aacacttcac gaagaaaagt ctccggattg atttcgcatt
    25441 gagtggaaat tgggatttcc aagccgccgc catacaacaa ctccgggaag aacctgtctg
    25501 ggcagggccg gtcaaaaact tgatcgatcc gtttggttat ggagggtatt atattaatgt
    25561 atatgataaa gccggtaaag agttgatcta ctcacgagga ttcaatacgt tattcgaaga
    25621 atggagaagt acagagcaag cgaagaccga gacacaatct tggacaaata gcatctctat
    25681 cccctatccg aaagctcctg tcatcattga gattacggca agagacaagg ccgacatgca
    25741 gttccatctt ttattgaaac aagagattga tccggccagt atttttattg accgggggaa
    25801 actcaaggaa aaccggatca caaaaatcca atataacggg gattcctccg ggaaagtaga
    25861 cctcgtattc ttagcggaag gttatacggc ggacgagcaa gagaaatttg tagctgatgc
    25921 caaacgtttt acggaggcat tgtttaagac cccgccttat gacactcgcc gggaagattt
    25981 caatgtctgg gcagtagatg ccgtttcgga agaatcggga acagatgtat ccggtaaagg
    26041 tatattcaag aataccgcat tgaattccgg ttattatacg tttggggtag atcgctattt
    26101 aaccaccccg gatatgaagt ctatacgtga cgccgtatgg aacgctcctt gcgacgcaat
    26161 cttcatcttg gtaaacacgg acgcttacgg tggtggcggt atgtataatt tttatgccat
    26221 gggaaccgcc gataacccac gtaccccagt cgtattcgtt cacgagttcg gacatagttt
    26281 cgccggccta gccgatgaat acttcagttc cgaggtcgct tatcaagatt tttataattt
    26341 gaagtacgag ccttgggaac cgaacatcac gaccttggtt aacttcgatg ctaaatggaa
    26401 agatcttctg ccggctaata caccggtacc taccccatta gatgacgctc ataaagataa
    26461 ggcaggcgta ttcgagggag gcggttacat cgctaaaggc atttatcgcc cgatggatca
    26521 ctgtatgatg cgtgattacg ctccattctg tccagcttgt agccgggcga tcttacagat
    26581 gatcgattac ttcacggata aaccgataaa acattaaaag gaaagagcgg gtaccctaat
    26641 agctttgtta catcaactat taagataccc gccagcacta acctatcaac atttatttca
    26701 tcatcggaac ttctatcaaa agaactttag cgtgcttcaa gacttctatc gtaatgcttt
    26761 cggtttccca gaatccggcc ccgtcacgct tagacaggat cgtattactt acctccacct
    26821 ctccgtcaat cacgaataaa taaaccccat tatttttact atgtagctta tactccttta
    26881 cttgaccggc atctaggttt cctaaagaga accaagcgtc ttggttgatc gacgcaggag
    26941 cgctaccatc cggagcgatg atcaaggaca acttattctt ttccgaagta accggacgca
    27001 cgtcataact ggcataatga ggcttggtat tctcctcacg gggaaatacc catatttgca
    27061 agaactccaa ttgttcatta ccgctgtcgt tgaactcact atgcacgata ccggtaccgg
    27121 cgctcatcac ctgaatatct cccggtgtaa tcacctcgct attctttatg ctatccccat
    27181 ggcgtaaata tccctttaac gggatggaga taacctccat attcttatgt ggatgcatat
    27241 cgaatccctc acccggcgcc acggaatcat cattcaatac acgtagcatc ccgaaatgaa
    27301 ccctttccgg attgtaataa ttagcaaaac taaacgtgtg atgtgttttc aaccaaccgt
    27361 gattcgcata ccctctggat tgagccttat caactacaac tctcatattt tcctcctttt
    27421 taaatctaca ttaataacaa atccataact ataaatgttg cgtgacgcat atttcgaaca
    27481 tttcatgtaa acatgtgatt catatgtgaa cagaaatcgc tacttttgcg caattaaaaa
    27541 aactcatcct gtaaatataa aatcttatgg caatctactt aaacgatgta tcgagaacat
    27601 ttggtgagta tttacttatt cccggtttaa ccaccaaaga atgtattccc gcaaacgttt
    27661 cattgaaaac gccgcttgtg aaattcaagt ctggcgagaa atccgctatt gaattaaata
    27721 ttcctttcgt ttccgcgatc atgcaatcgg tttccggccc taaactggca atcgagttgg
    27781 ctcgcaacgg aggactttcc ttcatcttcg gctcgcaacc aattgagaac caagcggata
    27841 tggttcgcaa agtaaagaaa ttcaaggccg gattcgttat cagcgactct aaccttacgc
    27901 ccgagaatac cttggccgac gtgcttgagc tagtccgccg gacagaacat tctacgattg
    27961 gtgtgacaga tgacggtacg cctaacggca aattgctagg tatggtaacc agtcgcgatt
    28021 accgtgaagg caaagacccg atcgacatga aagtgaaaga tttcatgacc ccgttcgcta
    28081 aactaatcgt tggcgagcta ggcatgacct tgaaagaggc gaaccagatt atctgggatc
    28141 ataagttgaa tacattgcca atcatcgaca aggatcagaa gcttcaatac ttcgtattcc
    28201 gcaaggacta cgatagccac cgtgagaatc cgaaagagtt atccggcgga gataagaaat
    28261 tattagtagg tgccggtatc aacacccgcg actataagga acgtgttccg gcattggtag
    28321 aggctggcgt tgacgtattg tgtatcgact cttccgacgg ctattccgaa tggcagtacg
    28381 agaccttgca ctggatcaag gatacctacg gagacaaggt actggttggt gccggaaacg
    28441 tggttgacca agatggtttc aactacttgg ctgacgccgg agcggatttc atcaaggtag
    28501 gtatcggtgg tggttccatc tgtatcaccc gtgagcagaa aggtatcggt cgcggacagg
    28561 ctaccgcctt gatcgacgta gcgaaagctc gtgacgagta tttcaagaga cacggcgttt
    28621 atatccctat ctgtagcgat ggtggcttgg tacacgatta ccatatggta ttagcgttgg
    28681 ctatgggtgc cgacttcctg atgatgggcc gttatttcgc ccgcttcgac gagtctccta
    28741 cgaagaagat gaaaatcgga aacaacttcg tgaaggagta ttggggtgag ggatctaacc
    28801 gtgcgaagaa ctggcagcgc tatgacatgg gtggaaacga gtccttgaaa ttcgaggaag
    28861 gcgtggacag ctatgtaccg tatgccggaa aattgaaaga taatttaaac gtaacattgg
    28921 gtaagatgat cgctacgatg tgtagctgcg gttccatctc tatccaagag ttgcagcagc
    28981 atgccaagat cacgcttgtc tcctctacaa gtatcgttga gggtggcgct cacgacgtga
    29041 tcctgaaaga gcagaattaa ttacaatatg tattctagta gaggcgtggc acgctacgtc
    29101 tctactattt acacattcaa ataatttacc atgaaaaatc tattacttac agttatcctt
    29161 ttgtgctttt gtttgccatt cgtaaaagcc gccgatcaaa agatgatctt aatctcgacc
    29221 aacgagacgg acttgatttt acaagtagcc cccaacggac ggctctacca aacttatctg
    29281 ggaaataaat tagtaaacga atccgaattt gagaacctct catggaatat ccaagccgga
    29341 acggatggca gcgtatcaac ccgtggatgg gaagtatatc cttgctcagg agcggaagat
    29401 tatttcgaac cggctttcgc catccagcat aacgacggaa acatgactag catattcaag
    29461 tatgtttcca gcgaatctaa gaaactagac aataacgtta cggagacaat tatctccctg
    29521 aaagacgatg tatacccagt ggaggctaaa ttacattatg taaccttcgc taaagaaaac
    29581 gtgatcaagg cttggactga gattcgtcat atggagaaaa aaccggtcac gattacccaa
    29641 tacgcttcca atatgcttta tttcgagagt cctcgctatg tattgaccga gtttagcggt
    29701 gactgggcca aggaagtaca gatgagcagc caagacttga aattcgggaa aaagattatc
    29761 gatacgaaac taggctcccg tgccgctatg cacgcttacc cgttttttga gattggatta
    29821 ggtgccccgg ccagtgagaa tacaggagat gttttaatgg gaacgatcgg ttggactgga
    29881 aactaccgct ttacgttcga ggtggacaac gccggtaacc ttcgtgtcat ctccggcatc
    29941 aatccctatg cgtccgccta tgaattgaaa ccgaacgaat ggttcgtcac tcctgagttt
    30001 atctttacat tgagtaatca aggaaccgga aaagccagtc gtgatatcca tgattgggca
    30061 cgtaattacc agatcaagga tggtaaaggc gatcgcctta ccctactgaa caactgggaa
    30121 tcgaccggtt tcaatttcaa cgagaagaaa ttggaggaat taatgaaaga agccaagcac
    30181 ctaggtgtag atatgttctt gctggacgat ggttggttcg ctaataaata ccctcgtcaa
    30241 aacgataagg ccggattggg cgattgggag gttacacacg ataagttgcc gaacggcatt
    30301 cctcatctgg tgcagaccgc taaagatgcc ggcgtgaaat tcggtatctg gatcgagccg
    30361 gagatggtaa accccaagag cgaacttttc gagaaacacc cgaattgggc gatccatcta
    30421 ccgaatcgtg agacttatta ctaccgcaat caacttgtct tggacttaag taacccgaaa
    30481 gtacaggatt acgtattcag cgtagtggat aatatcatga ccgagaatcc ggatctggct
    30541 ttcttcaaat gggattgcaa cagcccgatt accaatgtct attcccccta tcttaaaaaa
    30601 aagcagaatc aattgtatat cgaccatgta cgaggtgtct ataacgtatt caaacgggta
    30661 gccgagaaat accctcacct actgatcatg ctttgctccg gtgggggtgc ccgttgtgat
    30721 tacgaggcat tgaaatattt cacggaattc tggtgcagcg acaacaccga tccgatcgag
    30781 cgtttgtata tccaatgggg attctcccag tttttcccgg caaaggcaat gtgtgcccac
    30841 gtgactagct ggaacaagaa tacctccgtc aagttccgta ccgacgtggc catgatgtgt
    30901 aagatgggct tcgatatcag cttgaaggaa atgaacgacg acgagatgaa atactgccaa
    30961 gaagcggttg ccaactacaa acgtctaaag ggcacgatcc tcgacggcga tctttaccgt
    31021 cttgtttccc cctacgagac caaccattca tccgtgatgt acgtggataa ggcaaaaagc
    31081 aaatccgtcc tattcgctta tgatatccac cctcgcttcg gagaaaagac tttccccgta
    31141 aagctacaag gattggaccc gaataagaaa tataaggtac aagagataaa cctcatgccg
    31201 ggccagaaat cgaccttggt taccgacgga ggtaccttca gcggagattt cttgatgaaa
    31261 ataggaatga acgtgttctc tacggctcat gcccgtagca aggtcataga gctgaccgag
    31321 gttcattaac tgtcaattgt caactatcaa cagtcagcta aacatggaca ttatccacga
    31381 aataacccca ctatcggaaa aggattgctt ctacatcgta gaccgacgta agacagaatt
    31441 tacctatccg atccattgcc acttggagta cgagctcaat ttcattgagc acgctccggg
    31501 ggtaaggcgt gtggtcggtg attccgcgga agtgatcgga gaatacgagt tagtattgat
    31561 aaccgggaaa gaactggaac atgtctggga gcagaacgca tgtaaatcgc ctctgatcca
    31621 tgagatcacg atccagttct ctcccaatct cttcgggaat aatatattgg agaaaaacca
    31681 attcaacagt atccggaaaa tgttggagaa agctcaatgc ggcatcagtt tcccgatgtc
    31741 ttccatcttg aaggtttacc atttactgga aaaactggtt tccgaggagc aaagttttta
    31801 tgcggtcatc aacttcttga ccatcttgta tgagctttcc atcgaggagg actacaaagt
    31861 attggctagt tcctcgttcg ctaaaataac agatatacat tccgagagtc gtcgtatcca
    31921 aaaagtacaa aattacatca acgagcgata ccaacaggat atccgcctga acctactggc
    31981 tgaactcgta ggtatggccc cttccgcttt cagccgtttc ttcaagttga ggacagggaa
    32041 gaccctctcc gactatatca ccgatatccg tatcggttac gccgcccgca tgctggtgga
    32101 cacgcaacga tccatcgcgg agatttgtta tgactg
//
LOCUS       DBMDTB010000036        32092 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_542_length_32092_cov_11.182676, whole genome shotgun sequence.
ACCESSION   DBMDTB010000036 DBMDTB010000000
VERSION     DBMDTB010000036.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 32092)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 32092)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32092
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_542_length_32092_cov_11.182676"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..2646
                     /locus_tag="ACZPB4_07735"
     CDS             <1..2646
                     /locus_tag="ACZPB4_07735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004866 - endopeptidase inhibitor activity
                     [Evidence IEA];
                     GO_process: GO:0010951 - negative regulation of
                     endopeptidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-2-macroglobulin family protein"
                     /protein_id="HIR1098147.1"
                     /translation="EGRRNTDGSESATMLSFKTDKDSYTPGEKMVVTFPSTKGSRAII
                     SIENGVRVLSLTEHTCEDKQTTVRLDVTKDMQPNAYVYITLLQPHGITKNDLPIRLYG
                     VVPFTVTSPESHLTPVIQSPAELKPDASYTISVSEKNGKEMAYTLAIVDEGLLDLTRF
                     RTPEPWKAFNAREALGVNTWDLYNYVVGAYGGRIEQLFSIGGDDALNKGPKAIVNRFK
                     PVVRFDGPFLLKKGKTARHTYQMPNYNGRVKIMVVAGNGEAYGHADKSVMVRKPVMLL
                     GTLPRVIGVGEEMVVPATVFATEDGVGAVNVSIACSSNMEVVGEATRSLSFERKGDQQ
                     ASFRIRVKKNPGIGKVTITATGKGDKSVYETELEIRTVRRPQVKVTAATLEAGKSWKE
                     TVAMPGATGTNQLTLEVSDIAPVNVSSRLSYLLGYPHGCLEQITSKGFPQLYISSFTD
                     LTLQQAKSTEEAVKEVIRRLRSYQTVDGAFAYWPGGTSSNGWGTVYATHFLLEASKKG
                     YLVPEAMKQSVLNNLRRVARNWKPVTSYYKDSEEATQAYRLYVLALAGSPEMGAMNRL
                     KEMKDLTSMSRWSLASAYALVGREDVAQDLISKTTALPSGYSEHDETFGSDVRDQSIQ
                     LMTLCLLDKGKEAATLVEELSKQLSSDDWLSTQSTAFALVALSDYLAKYRVDGAMDFT
                     YACGGKDGQVKTDKNIWSETLLDKAGTSASVELKNTGKSTLFARIITEGIPEQGEEKA
                     YANGVSLAVSYVDLNGSPVNVAQLEQGTNFSAVVTVKNPSARGYNNLVLSEIFPAGWE
                     ILNTRFLNESATDSLSAGVNYQDIRDDRVYSYIDRLPAGSQVTVKINLCAVYPGRFYL
                     PPVYCEAMYDYLIRANTAGQEVTVF"
     gene            2859..3230
                     /locus_tag="ACZPB4_07740"
     CDS             2859..3230
                     /locus_tag="ACZPB4_07740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA];
                     GO_process: GO:0006397 - mRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA recognition motif domain-containing protein"
                     /protein_id="HIR1098148.1"
                     /translation="MNLYISNLSYNISDEDLRLLFADYGEITSAKVIMDRETGRSRGF
                     GFVELSDDELAKKAIEELNQASYDGKVINITEARPREDRGDRGGRFNNNRGGGYGSNR
                     GGGYGSNRGGGYGSNRDGGRY"
     gene            complement(3259..4185)
                     /locus_tag="ACZPB4_07745"
     CDS             complement(3259..4185)
                     /locus_tag="ACZPB4_07745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIR1098149.1"
                     /translation="MNTRLSANLSVLGTSLMLILSFSFGFHSYTEAKKTIVTDLNQAL
                     QQTILQNSHQWMSQDSIRTYANLSKHFGNPVSIESYNKDFSDALSYTPDKKKTGIVIH
                     VLNKDPQTENAPANANKKLNEYYIASDTIIWASSIANSPNATTDHIGISFQGYANCST
                     FAVIGLSDKSLPGLFLGLAFLSATLPLLLKRYRKELIMPQPIHPGKTISFGNLNLSCE
                     TASFYKENEEKLKLTPQQYALMEMFFLSPTHILNRSDICESLWPGKINADETLNTLIR
                     RLRPLVEENSNLKITTDRGRAYVLEIKKSDHL"
     gene            4417..6636
                     /locus_tag="ACZPB4_07750"
     CDS             4417..6636
                     /locus_tag="ACZPB4_07750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor domain-containing
                     protein"
                     /protein_id="HIR1098150.1"
                     /translation="MKRFLMMMTLIGLVGNWNSTLTAQLVSPDSLYLNEDLPEINIVA
                     VKPLIKAEADKTTYSIAEDPDSRTYTLLEMLRKVPLVTVDGEDNVKVNGQSSFKIYMN
                     GRPSNMFSNNPKEVLRSIPASMIKKVEVITDPGARYDAEGVSGILNIVTKGAEFEGYN
                     ASINTTVMNLFKSVGGFATLKYGRLSLSGNYTFSQQSSESESDYLRTQSEDGGKLRML
                     SDVDVKYPAHYGSLEGSFEIDTLNLISLSGNLNIGNSNSIWNSHYSRLDKEGEEIYAY
                     NEDMSKKNEWGSASLKADYQRLFKRNKEEMLTLSYQYDYIPNDIYSVFYDKDKMGNVS
                     LPQLEADYTRQISHARTHEHTAQLDYVNPFTSIHSIEGGLKLIRRSSTSHATSEVKEL
                     DEGVWLPADLQPLVEYRHVQNICSAYAGYGFKYGKWSLNPGIRMEHTWQDVTYKQGEG
                     KDFNYRVTDWVPSWTSAFRLDDRSLFRLAYNLRLRRPNISYLNPTVFVSGTSISYGNP
                     GLVSEKHHRLSASYSYYGTKLNVQASVLCTLGKGVIDEYLFIDSANVVNSTYDNLVDV
                     KAAGGNLYLSYNPSPRTSVSLNSMLHYLDLRAQEGNEVYDTDVRNSGFCGSAFVDFSQ
                     KFKYGWRFVLSGGYVRSEPNVGMDSYGFYFYGLSVVKSFLKDKLTCTLRAQDFLGDHK
                     TIQINERYPDFHIRQTERMFSRGFGIAISYRIGDLKASVKKAGRSIRNDDLLDALDK"
     gene            complement(6782..7012)
                     /locus_tag="ACZPB4_07755"
     CDS             complement(6782..7012)
                     /locus_tag="ACZPB4_07755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6722 family protein"
                     /protein_id="HIR1098151.1"
                     /translation="MGNFEKIIIKKERDKIRRETLGKFFFDLAKLVFAAIVLGEILLL
                     QENVFDKSCWVMIMTGLSVTYSLAWLGNKILK"
     gene            7142..9484
                     /locus_tag="ACZPB4_07760"
     CDS             7142..9484
                     /locus_tag="ACZPB4_07760"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HIR1098152.1"
                     /translation="MNVEEYLNQLNESQREAVVYNEGPSLVVAGAGSGKTRVLTYKIA
                     YLLQLGLPPYSILALTFTNKAAREMKERIAAITGDQTARRLWMGTFHSIFSRILRNEA
                     EHIGYPSNFTIYDATDSKSLLKSIIKEMQLDDKVYRLGMVQSRISNAKNSLITYTAYE
                     QNKELVESDMNAKVPLLREIYKRYQSRCLQAGAMDFDDLLLQTNILFRDHPAVLEKYR
                     NFFRYVLVDEYQDTNFAQHLIVQRLCERHGHICVVGDDAQSIYSFRGANIDNILQFKN
                     LYTGCRIFKLERNYRSTQNIVNAANSLIDKNTRQIPKTVYSEKEAGNKVSVFTSYSDY
                     EEGYTVAARINEMHGILGKFSYADFAILYRTNAQSRILEEALRKRGIPYKIYGGLSFY
                     QRKEIKDVISYFRMIVNPHDEEALKRIINYPTRGIGDTTVGKLVGAATEYGVSLWTVL
                     QAPLEYSLPINNGTAKKLSDFRSLIEVFIEENKKLSAEELATLVVKRSGIVSDLFQDR
                     SVEGVSKQENLQELLKGIAEFCEIRREEGMEQVAMSDFLAEVSLLTDQDNDKEENSDK
                     VTMMTVHAAKGLEFTNVFVVGLEEDLFPSSLSKDNPRAVEEERRLFYVAITRAEQNCV
                     LSYAKSRYRNGKTDMCTPSRFLKDIDAKYLDMPSDAGASDAFASARERYGRPAFASPF
                     RQPRAVEDDFVSPVKQAAQRQGHLTKLKNTMESSFSAAPATDLSGLHVGSKVRHDRFG
                     EGEIVSIEGEGGNAKATVAFDHFGQKQLLLKFAKLTMLND"
     gene            9896..11035
                     /gene="nspC"
                     /locus_tag="ACZPB4_07765"
     CDS             9896..11035
                     /gene="nspC"
                     /locus_tag="ACZPB4_07765"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_process: GO:0045312 - nor-spermidine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HIR1098153.1"
                     /translation="MIDINKIPSPCYVMEEKLLRNNLSLIKSVKERAGVNIILAFKAF
                     ALWKAFPIVREYIPFSTASSKFEAQLAFEEMGSPAHTYSPAYTEADFPLILRYSSHVT
                     FNSLSQFHRFYPMVRADGNRVSCGLRINPEYSDVETDLYNPCAPGSRMGVTGDLLGDK
                     LPEGIEGLHFHTLCESTSYDLERTLAEVERRFGRFLPHVKWLNMGGGHLMTRKGYDVE
                     HLIALLKGFKERYPNLELIMEPGSAFAWQTGFLLTTVVDIVENHGIKTAIIDASFTCH
                     MPDCLEMPYKPAIRFATDAVEGKPTYRIGGNSCLSGDYMGDWSFDKPLEIGDKLIFED
                     MIHYTIVKTNMFNGIPHPSLALWSKDDQLVMYRTFGHEDYKNRMD"
     gene            11056..11295
                     /locus_tag="ACZPB4_07770"
     CDS             11056..11295
                     /locus_tag="ACZPB4_07770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098154.1"
                     /translation="MTMTANELKYTYMEEAMSILDNEELMRKALSLLRNLKEKTFSPA
                     KRSEREVLEEAFQSVKDLKAGKITSRPLEDLLNEL"
     gene            11285..11626
                     /locus_tag="ACZPB4_07775"
     CDS             11285..11626
                     /locus_tag="ACZPB4_07775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module toxin RelE"
                     /protein_id="HIR1098155.1"
                     /translation="MSYKIEALPPFAKEVKYLAKRYKSLKEDILRLRDELLENPLSGT
                     DLGGGLRKVRMSIRSKSQGKRGGARVITFTVLVSVDEGTIYLVTMYDKSEIESMSVKE
                     IRKLLDKCDLK"
     gene            11650..12603
                     /gene="ftsY"
                     /locus_tag="ACZPB4_07780"
     CDS             11650..12603
                     /gene="ftsY"
                     /locus_tag="ACZPB4_07780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HIR1098156.1"
                     /translation="MGIFSFFSKDKKETLDKGLSKTKESVFSKITKAIAGKSKVDDDV
                     LDNLEEVLITSDVGVDTTLKIIDRIEKRVARDKYVTTQELTTLLRDEIASLLTENNTE
                     DAEGFALPEGKKPYVIMVVGVNGVGKTTTIGKLAYQFKKAGKKVYLGAADTFRAAAVE
                     QLVIWSERVGVPIVKQNMGSDPASVAFDTLSSAKANDADVVIIDTAGRLHNKINLMNE
                     LTKIKNVMKKVIPDAPHEILLVLDGSTGQNAFEQAKQFTAATEVNALAVTKLDGTAKG
                     GVVIGISDHFRIPVKYIGLGEGMEDLQVFRKREFVNSLFGE"
     gene            12600..13898
                     /gene="rimO"
                     /locus_tag="ACZPB4_07785"
     CDS             12600..13898
                     /gene="rimO"
                     /locus_tag="ACZPB4_07785"
                     /EC_number="2.8.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008172 - S-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016782 - transferase activity,
                     transferring sulphur-containing groups [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0018339 -
                     peptidyl-L-beta-methylthioaspartic acid biosynthetic
                     process from peptidyl-aspartic acid [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12 methylthiotransferase
                     RimO"
                     /protein_id="HIR1098157.1"
                     /translation="MRKNKVDIITLGCSKNLVDSEQLMRQFVANGYTVEHDPHKINGE
                     IVVVNTCGFIGDAQEESINMILELGEQKQKGRIGKLFVMGCLSERFLKDLEKELPEVD
                     RFYGKFNWKELISDLGKSYHQELATERVLTTPRHYAYVKIGEGCNRTCSYCSIPIITG
                     AYQSRPMDEIVDEVRGLVAQGVKEFQMIAQDLTFYGLDRYKRMALPELVERVSDIPGV
                     EWIRLHYGYPSHFPYDLLPVMRERDNVCKYMDIALQHISDPMLKMMRRNITKAETYEL
                     LERMRREVPGIHLRTTLMVGHPGETEQDFEELIRFVKDIRFERMGAFAYSHEEGTYAY
                     QHYKDEIPQEVKQDRLDYLMRVQEGISADVNASKVGQTFRVIVDREEEDFYVGRTQYD
                     SPEVDPEILISKDTPLSPGSFYQVKVIDAQAFDLYGKVLN"
     gene            13976..14266
                     /locus_tag="ACZPB4_07790"
     CDS             13976..14266
                     /locus_tag="ACZPB4_07790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005642933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030527 - structural constituent of
                     chromatin [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HIR1098158.1"
                     /translation="MKNKELITELANRMDWTSKEVSDMLSALSSVVSSKLVDNDTIYL
                     QGFGQFEVKKKAERISVNPANGKRYLVPPKLVPVFKPGTTVKNRLKELGDHE"
     gene            14259..15350
                     /locus_tag="ACZPB4_07795"
     CDS             14259..15350
                     /locus_tag="ACZPB4_07795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030527 - structural constituent of
                     chromatin [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HIR1098159.1"
                     /translation="MNNRLNIQDLAGLLSERTGKDRGEVERFLRDFISVVSEGVYTDK
                     IVKVKGLGTFKIISVEKRESIHVNTGERFLIPEHYKFSFLPDKDLREQVNKPFSIFET
                     TEINENVDFSDMDESVEEKEAEDESVEEVMPDKEIPLANTQPKEKPEPILEPEPEPLP
                     EPEQAFDPEPSSVSEPERGLEPELPAEPSPIPERPEEQARRKPEEKGVLMIVAFLIIV
                     ISVFFYLGRNNWKPAPAQEEVITEAKNTAKDTVQESAWMLHPDSVAEKTPHTEPEPYV
                     EPAPKPLGQVKIKHGDRLTVIALEYYGNKLFWVYIYQHNKAVIKDPNNVPIGTVIEIP
                     APESYGIDAKSRESREKAAALQTEILAGE"
     gene            15519..16514
                     /locus_tag="ACZPB4_07800"
     CDS             15519..16514
                     /locus_tag="ACZPB4_07800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008761573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HIR1098160.1"
                     /translation="MSQTVDIRELNERIESKSSFVNMITMGMDKVIVGQKHLVESLLI
                     GLLSDGHILLEGVPGLAKTLAIKTLSSLIDAKYSRIQFTPDLLPADVIGTMIYSQKSE
                     EFQVKQGPIFANFVLADEINRAPAKVQSALLEAMQERQVTISEHTYKLPKPFLVMATQ
                     NPIEQEGTYPLPEAQVDRFMLKVIINYPKKEEEKLIIRQNISGERPEIKPILTKEEIL
                     DARNVVREVYLDEKIERYIVDIVFATRFPAEAGLPNLASMISFGASPRASINLALAAR
                     AYAFIKRRGYVIPEDIRAVCHDVMRHRIGLSYEAEANNLTSEEVISEILNKVEVP"
     gene            16515..17384
                     /locus_tag="ACZPB4_07805"
     CDS             16515..17384
                     /locus_tag="ACZPB4_07805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013547839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HIR1098161.1"
                     /translation="METSELLKKVRRIEIKTRGLSRNIFAGQYHSAFKGRGMAFSEVR
                     EYQYGDDIRDIDWNVTARYVRPYVKVFEEERELTVMLLIDVSGSRDFGSVNVMKKEVI
                     TEIAATLAFSAIQNNDKIGVVFFSDKIEKFIPPQKGKKHILYIIRELIDFHPEETRTD
                     ISQVLKYLTNAIKKRCTAFLISDFIDKEGFKDALTVANRKHDMVAIQVYDRRETELPA
                     VGLMKIKDAETGKEQWIDSSSARVRAAYKEWWEKRQAKMSDTFKKCRVDSVSVRTEDD
                     YVKALIALFDKRN"
     gene            17394..18503
                     /locus_tag="ACZPB4_07810"
     CDS             17394..18503
                     /locus_tag="ACZPB4_07810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098162.1"
                     /translation="MKLIKKSILFLVAAASLAGGRAYAQRPLIDVAIDSAAILIGEQT
                     TLHLTVTADKDRPVQIVIPNDTLMTGVEVLNLSKADSTEIENDRLVIKQDVLITSFDS
                     SLYLLPPLKVIDGVDTVYSNQVALKVSTIPVNADKPEEFNDIKTVWKPPFVWADYYPI
                     IYGILLALFLICVIAYIVKRIRAKKSLIPFKKEEPKLPPHEQAIKELDEIKQQKLWQQ
                     GRSKEYYTLITDTLRKYIEERFGINAMEMTSGEILDLIRKNSEAQSVYENLRQILQLA
                     DFVKFAKMNPLPDENDLSMMNAYLFVNQTKEEEMVELVDSPLSDELTASGQEERQPAV
                     KAVDSPLSNEPVAPCQDDLTRYQPKSTNDTTNLKD"
     gene            18507..19493
                     /locus_tag="ACZPB4_07815"
     CDS             18507..19493
                     /locus_tag="ACZPB4_07815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004291042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vWA domain-containing protein"
                     /protein_id="HIR1098163.1"
                     /translation="MVFANPNYLYLLLLLIPMIGWYVYKLSKSQASLQVSSSEAFEAP
                     GATSWIVYLRHVPFVLRMVAVALLIVILARPQSTNSWSNSSTEGIDIMLAMDISGSML
                     AQDLKPNRLEAAKDVAASFINGRPNDNIGLVVFSAESFTQCPLTTDHTVLLNLFKDIQ
                     SGMIQDGTAIGLGLANAVSRIKDSHAKSKVIILLTDGSNNAGEIAPVTAAEIAKTFGV
                     RVYTIGVGTKGMAPYPFQTAFGVQYQNIPVEIDEATLKQIASTTGGQYFRATDNASLK
                     EIYSEIDQMEKTKISVQEYSKKQEEYKNWALLVFALLLVEILLRNTLLRNIP"
     gene            19507..20523
                     /locus_tag="ACZPB4_07820"
                     /pseudo
     CDS             19507..20523
                     /locus_tag="ACZPB4_07820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017322.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
     gene            20527..21231
                     /locus_tag="ACZPB4_07825"
     CDS             20527..21231
                     /locus_tag="ACZPB4_07825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HIR1098164.1"
                     /translation="MLFLCAGTVSAQKAERKNVREGNKLYESEKYTESEIAYRKSLEV
                     NPRSTEGTYNLGNSLYKQGKFPEAAEQYQLIAGQGEKMVATPEGKARLSEVYHNMGNI
                     FMQNKDYGKAVEVYKQSLRLNPKDDETRYNLALAQKLLSDQQNQDQSQDQQNDDKQEN
                     KDQKDDQQQQQQQQPQDDQKQDKTQEQQQQGEQMSKDNAQQMLDAFLQDEKDTQEKVK
                     KAQMQQQQRRKTEKEW"
     gene            21264..23075
                     /locus_tag="ACZPB4_07830"
     CDS             21264..23075
                     /locus_tag="ACZPB4_07830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BatD family protein"
                     /protein_id="HIR1098165.1"
                     /translation="MRKLIFLFILMLTVGGATKAADVTFKASAPQAVVMGEQFRLTFT
                     VNAEGKDLRVQEMPDFDVLMGPSQSTSYSSSWVNGKSTSETTVTYTYVLMPKKEGTFN
                     IAPATIKVNGSNYTSNGLAIKVLPADKAGKQEAETTTASGAISNDRLFVKMDVSKRSV
                     FEQEGFLVTFKVYSLENFSITGLKYPEFEGFLVQEVELPQEKQLTLENYNGRNYQSAV
                     MRQVILYPQRSGKITIEGGKYDAVVRVRMQQAGGGSIFDSFFDSYRDVSKVLTTSPVT
                     IDVKPLPSGKPASFSGAVGTFSMTADISSNNVKTDEAVTIKVKITGNGNVKLVKNPEV
                     VFPNDFDVYDPKVEMDIKTTTAGVSGSKTIEYMAIPRYAGDFEIPAIAFSYFDIKSGS
                     YKTIKSEPYKLHVEQGKGGSGSSPVVSNFSNKESVKYLGKDIRYLKTKGFSFIEGGDG
                     IFFGSFMYYLCYIVPAILFIVFFFIYRKQVKENADIALVRTKKANKMAVRRLKNAGKL
                     MKENKKEEFYDEVLRALWGYLSDKLSIPQSDLTKDNVETELAKYGVDESLTNEFMDIL
                     NTCEFARYAPSQASDAMDKLYELTVDAIGKMENTIKK"
     gene            23080..23847
                     /locus_tag="ACZPB4_07835"
     CDS             23080..23847
                     /locus_tag="ACZPB4_07835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HIR1098166.1"
                     /translation="MKMTINLRKVLFFLLTLCLIGSAYAQDTALKEAEVAYTKEDYAK
                     AIELYEGILKSNGESAAVYYNLGNAYYKAGKIAPAILNYERCLLLDPGDSDARFNLQM
                     ARQKTIDKIEPVGDFFLVKWFKSVENLGSADSWAKTGIVCFLLFIGCLILFFFSRWVR
                     LKKIGFYLGVLFIIMVVFANIFASDQKDEMINRKHAIVFAPTVTVKSSPDASGTDLFV
                     LHEGTNVTVKSTLGEWSEIELEDGNVGWMPSKDIEKI"
     gene            23851..24543
                     /locus_tag="ACZPB4_07840"
     CDS             23851..24543
                     /locus_tag="ACZPB4_07840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HIR1098167.1"
                     /translation="MLEQLLVWERDAFFMLNGSDSAFLDRFMWIYSGKAVWLPLAFFI
                     LVVLCYKKNWKEWLLILLAIVLTITLCDQFASHVCKPIFTRFRPTHHPDFMDQVRVVF
                     GYRGGMYGFISSHAANAFGFATLMALIFRNKLFGWTIFFWAILTSYTRIYLGVHFITD
                     IIPGALSGLLFGYLVYLLYHYIRPKLIPADSWVCPEAIYSDIRKRWITYAIWLTILLI
                     ALFNEQLVSCLI"
     gene            24683..24955
                     /locus_tag="ACZPB4_07845"
     CDS             24683..24955
                     /locus_tag="ACZPB4_07845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HIR1098168.1"
                     /translation="MTKTITFNELRRIKDSLPDGSTQRIADELGLKVETVRNYFGGHN
                     FQDGRSCGFHIEPGPDGGLVVLDDTTIFERALQILAESQDAEAQKA"
     gene            25070..26188
                     /locus_tag="ACZPB4_07850"
     CDS             25070..26188
                     /locus_tag="ACZPB4_07850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HIR1098169.1"
                     /translation="MEDKLVTLAIHTFEKAQILKTILETEGIEVYIHNVNQIQPVVSA
                     GVRVRIKESDLPHALRIIEDNKWFEEPKEEEAKVNAVKKVLIPIDFSDYSAKACELGI
                     NYAHAVGAEVMIMHAYFSPYFPSAIPMGDTLAYQVNEEESVQHILQRVRIDMENICTH
                     INRKMSSGELPKVKYDYVLREGLPEEEIIAYSKEYHPTLIVMGTRGKSQKDMDLIGSV
                     TGEVIEVNRVPVLAIPENVPFTDLRDAKNIAFATSFNQRDLVAFDEFMEIIKGFDLNI
                     HLFNISTSNDEWNEIRLTGVREYFKKQYPHAHISHTVLADGDLLLAIEKFVRDKQIDV
                     IALSTYRRNILARMFNPSIARKMLFHTDTPLLVIDSKK"
     gene            26307..27071
                     /locus_tag="ACZPB4_07855"
     CDS             26307..27071
                     /locus_tag="ACZPB4_07855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098170.1"
                     /translation="MWERMFDLVLGLKKEHRLMIVITLIYAVTLFGITVDVEAMENWL
                     QLVGYTIRTLCIACIIQLSVFFLTNIFWKELNRGLNKTFVVISGNVLSLAFLLFPFSI
                     SYIDMTAESMKLSSLNTERNRIDSMVRYYENLKSLDSSFSENLDSLILEEKKTLIRVI
                     KEIDLKQFKIEEKQKRYEKPLVSILFLLQIFGFYILILYSSYFDRTNKVNRVIAVENI
                     PYRKKVRSYFCDKVLKPLVLLLSVFLWGFLFFLWLR"
     gene            27144..27749
                     /locus_tag="ACZPB4_07860"
     CDS             27144..27749
                     /locus_tag="ACZPB4_07860"
                     /EC_number="3.4.21.-"
                     /EC_number="3.4.21.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HIR1098171.1"
                     /translation="MITYLIIGITVVLSFICFSNRELFMKLAFIPYRTIRNHEYYRIV
                     THGFIHADMTHLLVNMFTFWSFGLYIERTFRYMGFGSGAYLAFYFGGMIVASLYDLIK
                     RRNDPYYVSIGASGAVSAVLFTSIFLDPWGKILFFAVLPVPGIVFGLLYLAYCQYMAK
                     QTGDNINHNAHFYGAIYGLIFPMLLEPSLLHLFLSQLTFKG"
     gene            27848..29296
                     /locus_tag="ACZPB4_07865"
     CDS             27848..29296
                     /locus_tag="ACZPB4_07865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HIR1098172.1"
                     /translation="MNKDNNLGRVLALLSLTLLMSFGLYSLPDTLFGYKIKKVDLLSD
                     FKVKEEKLSLDSLKQQLEQADTLQVDSVALRDSIMRSAGIDSAALALRDSLYKAVYAV
                     QGADSLGAHIEDYSLGHIGLQRFFAALKNRRELNRPVRVAFLGDSFIEGDIMVADFRS
                     GMQKEFGGRGVGFVPVTSVAAQFRPTVEQRASGWTTWSMLTDHEHGYTLSGMMFEANE
                     ENASIHVKTTKRYPELQTFSSLKLIYEQNKNTEMRLVCNASADTLQEMLPATSIVTQY
                     ELEGMFTEADFTFKNTPEFRALGVAMEDHSGVVVDNFSLRGNSGMILERLDVSRCQAL
                     NKIRPYDLIVLQYGLNVVSDSVMNYGWYSSRMVKVINHIQLCFPEADILMLGVSDRSR
                     QDDGEFETMPAVLALLHAQRQAAKKAGVPFWNVFGAMGGENSMVRFVELNWASKDYTH
                     LSFRGGREIADALLKALLSEKDFYDEAEKVVN"
     gene            29268..30599
                     /locus_tag="ACZPB4_07870"
     CDS             29268..30599
                     /locus_tag="ACZPB4_07870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDSL-type esterase/lipase family protein"
                     /protein_id="HIR1098173.1"
                     /translation="MMKRRKWLISLVVLGVIMGFSVPKPKAGINGDVSLDSLAVRDTV
                     ALPPLSYSMKVGKDTLILPDSSKAWNNFFNELDSLRAGKDTAITIVQLGDSHIQAGHL
                     SGRVMRLFQQAFGNAGRGWIAPFKLSKTNEPDDYFIKSVAKDWIAGRCIQHVRKTPIG
                     IGGIGIKSVSPSINLDVVITPNNGAGYEFNEAILYRGEKSMPMLPAGALKDSVQTFRA
                     DTVCVPGVLADTFRISCLTDTLQLQSTRRKEGTNTLRPASSFTNLYYGLTLKNGGRGI
                     LYHSIGVNGAMYVNYTDEAYVRQLALLKPSLLIISMGTNETFGRRFNTDEFSGQIEAF
                     LALVKKELPNTAILLTTPPECYRRVRSGKQRTYVRNDNTERAARAIRNVAKKEEVACW
                     DLFTTTGGKNSCRKWHSSRLMGRDRIHFTKEGYQEQGTLLFRAFMESYNNR"
     gene            30609..>32092
                     /locus_tag="ACZPB4_07875"
     CDS             30609..>32092
                     /locus_tag="ACZPB4_07875"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBOAT family O-acyltransferase"
                     /protein_id="HIR1098174.1"
                     /translation="MEYNILRDWLSNHQFTWEKLGDILTYHHNAPILFSSGLFFFLFI
                     GFLMIYMSLRKHTLARIIYVTLFSLYFYYKSSGLWFGLLVFTATSDFLIAQCISHTTS
                     VLKRKLFVTLSLCINLGMLGYFKYFNFLGELFTMAAGGEWLKMNIFLPVGISFFTFQS
                     ISYVIDVYRGRIQPLGRWIDYVFYVSFFPQLVAGPIVRARDFIPQMYKNPTVTRSEFG
                     EGLFLILCGLFKKTVISDYISMNFVDRIFDAPLLYTGVENLLGVYGYALQIYCDFSGY
                     SDMAIGIALLLGFRFNINFDSPYQSATITEFWRRWHISLSSWLKDYLYISLGGNRKGK
                     IRTYMNLMITMLLGGLWHGASISFILWGALHGIALAAHKFIMGHFSSFKALGCEMKPW
                     RRVLGVLITFHVVCFGWILFRATSMKAVGEMLSQIFTNFHPEVFMQFVSGYKGVFALM
                     VIGYVLHFMPKRSEDVLREIVTRSPLLIQAAILAIAIFIVVQFK"
BASE COUNT         8464 a         6657 c         8524 g         8447 t
ORIGIN      
        1 gagggccgac gtaacaccga tggcagcgag tccgccacga tgcttagttt caagaccgat
       61 aaggatagtt atacgcccgg cgagaagatg gtagtcacct tcccctctac gaaaggaagc
      121 cgtgcgatta tcagtataga gaacggcgtg cgtgtccttt ccttgacgga acatacgtgc
      181 gaggataaac aaacgaccgt gagactggat gtgacgaaag atatgcagcc gaacgcttac
      241 gtctatatca cccttttgca gcctcatggc atcacgaaga acgatttgcc gatccgcttg
      301 tatggcgtgg tcccgttcac ggtaacttct ccggagagcc atctgacccc ggttatccaa
      361 tctcccgccg agttgaaacc ggatgcctct tataccatat ccgtctccga gaagaatgga
      421 aaggagatgg cttacacgct ggcgatcgtg gatgagggct tgctggactt gacccgtttc
      481 cgtacgccgg agccttggaa ggcgtttaac gcccgggaag cgttgggcgt gaatacatgg
      541 gatttgtata actacgtggt tggcgcttat ggcggccgta tcgagcaatt gttcagtatc
      601 ggcggcgacg atgcgctgaa caaaggcccg aaagcgatcg tgaaccgttt caagcccgtg
      661 gtgcgatttg acggcccgtt cttgctgaag aaggggaaga ccgcccggca tacctatcag
      721 atgccgaatt ataacgggcg tgtcaagatc atggtggtag ccggaaacgg ggaggcttat
      781 ggacatgccg ataagagcgt gatggtacgt aagcccgtaa tgctgctagg aaccttgccc
      841 cgggtgattg gcgtgggcga ggagatggta gtacccgcta cggtattcgc taccgaggat
      901 ggcgtaggag ccgtgaatgt atctatcgct tgcagctcga atatggaagt ggtcggcgag
      961 gcgacgagga gcttgagctt cgagcggaaa ggggatcagc aagcctcgtt ccgtatccgg
     1021 gtgaagaaga acccgggtat cgggaaggta acgataaccg ctacgggtaa aggggataaa
     1081 tccgtttatg agacggaact ggagatccgt acggtacgcc gcccgcaagt gaaagttacc
     1141 gccgctacct tggaggccgg caagtcttgg aaagagacgg tcgctatgcc gggtgccacg
     1201 ggtacgaacc agttgacctt agaagtgtcg gatatcgccc ccgtgaacgt atcctcacgt
     1261 ctatcttatt tgttgggtta tccgcacgga tgtctggaac agatcacctc gaaaggattc
     1321 ccacagcttt atatctcctc gtttacggat ttgaccctgc aacaggcgaa atccacggag
     1381 gaggccgtga aagaggtgat ccgccgtctg cgctcttacc agaccgtaga tggggctttc
     1441 gcctattggc cgggtggaac gagcagcaat ggctggggta cggtttatgc tactcatttc
     1501 ttgctggaag cctcgaagaa aggttacttg gttcccgagg ccatgaaaca aagcgtattg
     1561 aataatctac gccgggtagc ccgtaattgg aagccggtta cctcttatta taaagattcg
     1621 gaagaggcta cccaagccta tcgcctgtat gtattggctt tggccgggtc gccggagatg
     1681 ggtgccatga accgcttgaa agagatgaaa gatttgacct ccatgagtcg ctggtcgcta
     1741 gcttccgcct atgccttggt cggccgtgag gatgtcgctc aagacctgat cagcaagacg
     1801 acggctcttc cttccggtta ttccgagcat gacgagacgt tcggcagtga tgtccgggat
     1861 caatccatcc agttaatgac gctttgcttg ttggataaag gcaaggaggc cgctaccttg
     1921 gtggaagaat tgtccaaaca actttcttcg gatgattggt tgagcacaca atctacggca
     1981 ttcgctttag ttgccttgtc ggactaccta gctaaatatc gggtagacgg ggccatggat
     2041 ttcacgtacg cttgtggcgg aaaggatgga caggtgaaaa cggataagaa tatatggtct
     2101 gagaccttat tggataaggc ggggacctcg gcgagcgtcg agttgaagaa cacgggtaaa
     2161 tctacgctct tcgcccgtat cataaccgag ggaataccgg agcagggaga ggaaaaagcg
     2221 tatgcgaacg gtgtctcatt ggcggttagc tatgtggact tgaacggaag tccggtcaat
     2281 gtcgcccaat tggagcaagg tacgaatttc tccgccgtgg ttacggtaaa gaacccttcg
     2341 gcccggggat ataataattt ggtattatcg gagatcttcc ctgctggatg ggaaatactg
     2401 aatacccgtt tcttgaatga gtccgctacg gacagcttga gcgccggagt gaattatcag
     2461 gatattcgtg acgaccgtgt ttatagttat atagaccgtc tgccggcagg cagtcaagtg
     2521 accgtgaaga ttaatctttg cgcagtctac ccgggccgtt tctacctgcc tccggtgtat
     2581 tgcgaggcga tgtacgatta tttaatccgt gcgaataccg cgggacaaga agttaccgta
     2641 ttctaatttc gtggggggcg ggcaaacccc gcccttatat tttttcgaaa tttattggat
     2701 ttatagttgt atgctcgaat aaaaccatta cattcgcagc atatttgaga ttgatttaag
     2761 ttagtattag aaagtatttg ctcacaactt gatttgttag gtaaactttt ttagtcgaca
     2821 tactcagctc aattaaccat ttaattaaag tttacaaaat gaatctttac atttcaaatc
     2881 taagttacaa catctctgat gaggacttaa gactgttatt tgctgattac ggtgagatta
     2941 cttcagcaaa agttattatg gatagagaaa ctggccgttc aagaggcttc ggtttcgttg
     3001 agctgagcga tgatgagcta gctaagaaag ctatcgagga gttaaaccaa gcaagttatg
     3061 acggcaaagt catcaatata acagaagcca gacctagaga ggatagaggc gacagaggtg
     3121 gtcgtttcaa taacaacaga ggtggcggct acggttccaa cagaggcggt ggctatggct
     3181 ctaacagagg tggcggttat ggttctaacc gggacggtgg aagatattaa ttctatctag
     3241 ataaaaatgg aagagcgatc agagatggtc gctctttttt atttcaagca cataggctcg
     3301 tccacggtct gtcgtgatct ttaggttact gttttcctcc actaaaggcc gtagccttcg
     3361 gatcaaggtg ttcaaggtct cgtcggcgtt gatctttccc ggccataaac tttcgcagat
     3421 atccgagcgg ttcaagatat gcgtaggcga taggaaaaac atctccatca aggcatattg
     3481 ctgaggggtg agttttagtt tctcctcatt ctccttatag aaggaggcgg tctcgcaaga
     3541 aaggttcaaa ttaccgaaag agatggtctt tcccggatgg ataggctgag gcattatcaa
     3601 ctcctttcta taacgtttaa gcaataaggg cagggtagcg gataaaaagg caagcccgag
     3661 gaataggccg ggcaaagatt tgtccgatag cccgataacc gcaaaggtgg agcaattggc
     3721 gtacccttgg aatgagatcc cgatatgatc cgtggtagca ttggggctgt tcgctatgga
     3781 tgatgcccag ataatcgtat cgctggcgat ataatattcg ttgagtttct tgttggcatt
     3841 agcgggagcg ttttcggttt gaggatcttt attgagtacg tggatcacga ttcccgtttt
     3901 cttcttgtcg ggcgtataac tcaatgcgtc ggaaaagtcc ttgttataac tttctatgga
     3961 taccggattg ccgaaatgct tggatagatt ggcataggtg cgtatggaat cttggctcat
     4021 ccattggtgg gaattttgca ggatcgtttg ttgcaacgct tggttcaagt ctgtcacgat
     4081 cgttttctta gcttccgtat aactatggaa accgaagctg aacgagagaa tcagcattaa
     4141 ggaggtaccc aaaacagata gattggccga tagtcgtgta ttcattattc gctagattag
     4201 aattaacata aaaagaacgt tcgaaggtac taaatattat agaaggaaag tatccttttc
     4261 gataggattc gggatgaaat agacataaat ccagctaaat gaccggatgt catggaaatg
     4321 tcatggaaat gtcagctact tatccggcga ttatttatgt tgttgttgtc tgttgcctct
     4381 acttttgccc gaaaacaaat caaataagat gcagatatga aaagatttct gatgatgatg
     4441 accttgatag ggcttgtggg aaactggaac tcgacgttga ccgcccaact cgtctctccc
     4501 gattcattgt atttgaacga ggacttaccc gagataaaca ttgttgccgt gaaacccttg
     4561 ataaaggcgg aggcggataa gactacttac agtatcgccg aggacccgga ttccagaacc
     4621 tataccctgc tggagatgtt gcggaaagtc cctctagtga ccgtggatgg tgaggataac
     4681 gtgaaggtaa acggacaatc cagttttaag atttatatga atgggcgtcc ctcgaatatg
     4741 ttctccaata atcccaagga ggtcttgcgt agtatccccg ccagcatgat caagaaagtg
     4801 gaggtgataa cagatcccgg tgcccgttac gatgcggagg gtgtcagcgg aatcttgaat
     4861 atcgtgacga aaggagcgga gttcgaggga tataacgcga gtataaacac tacggtgatg
     4921 aacttattta agagtgtcgg tggtttcgct acgctgaaat atggccgatt atcgctttcc
     4981 ggaaattata cgtttagcca acagtcatcc gagagcgagt cagattatct ccgtactcag
     5041 tcggaagacg gtgggaagct ccggatgctc tcagacgtag acgtgaaata tccggctcat
     5101 tatggaagtc tggaaggcag tttcgagatc gatacattga atttaatctc cttgtccgga
     5161 aacttgaata tcggaaacag caactctatt tggaatagcc attatagcag gcttgataaa
     5221 gagggggaag aaatctatgc ttataacgag gatatgagta aaaagaacga atggggtagc
     5281 gcctccttaa aagcggatta tcagcgttta ttcaaacgaa ataaggaaga gatgctaacg
     5341 ctttcctatc agtatgatta tatcccgaac gatatctata gcgtgtttta cgataaggat
     5401 aagatgggta atgtctcgtt accccaactg gaggccgatt atacccggca aatcagtcat
     5461 gcccgcaccc atgagcatac ggcccagctt gattacgtga atccttttac aagtatacat
     5521 tccatcgagg gaggtttgaa gctgattcgg cgtagcagta cgagccacgc tacttcggag
     5581 gtaaaggagt tggatgaggg tgtctggtta cccgcagatt tacagccttt ggtggaatat
     5641 cggcatgtgc agaatatatg ctccgcctat gcgggatatg gatttaagta tggtaaatgg
     5701 agcttgaacc ccggcattcg tatggaacat acttggcagg acgtgactta taaacaaggc
     5761 gaaggcaagg attttaatta tcgtgtaacg gattgggttc cttcttggac ctccgctttc
     5821 cgcttggatg accggagttt gtttcgcttg gcttacaact tacgtttacg tcgcccgaat
     5881 atcagctatt tgaatcctac ggtgttcgtg tctgggacct ctatctcgta tggaaatccg
     5941 ggattggtat cggagaaaca tcatcgtctt tcggcgtcat acagttatta cggaacgaaa
     6001 ttgaatgtgc aagcttccgt gctctgcacc ttgggaaaag gggtgattga tgagtatctg
     6061 ttcattgatt cggcgaatgt ggtgaatagt acgtatgata atctcgtgga cgtgaaagca
     6121 gcgggaggaa acctttatct aagctataat ccttcgcccc ggacaagcgt gtcgctgaac
     6181 agcatgttgc attatctgga tttacgggcg caggagggga atgaggttta cgatacggat
     6241 gtgcgtaatt ccggcttttg tggctctgct tttgtcgatt tctcgcagaa gtttaagtac
     6301 gggtggcgtt ttgtcctgtc gggtgggtac gtgcgttccg agccgaatgt ggggatggac
     6361 tcgtacggct tttattttta cggcttgagt gtggtaaaga gcttcttgaa ggataaattg
     6421 acttgtacgc tgcgggcgca agattttctg ggagatcata agacgataca gattaacgag
     6481 cgatatccgg actttcatat ccggcagacc gagcgtatgt ttagtcgtgg tttcggcatc
     6541 gccattagct accggatcgg tgatttaaaa gcgagcgtga agaaggcggg gagaagcata
     6601 aggaatgatg atctgttgga cgccctagat aagtagggcg ggcacaggcc cgctccctac
     6661 ggtatcataa ctcgtccagc catttcttgc cgggtttcgt gtaaagccaa gcgataaata
     6721 aacctgtaat aactcctact actaagaata gggcacttaa tggatttaat atcatattct
     6781 tttattttaa aattttattt cctaaccaag ctaatgaata ggtgacacta agacctgtca
     6841 ttatcatgac ccaacaactc ttatcaaaaa cattctcttg caaaaggagt atttctccca
     6901 atactatagc ggcgaaaacc aacttagcca aatcaaaaaa gaacttccct aaagtctccc
     6961 tcctgatctt gtcccgctct ttcttaataa ttattttctc aaaatttccc atttccccat
     7021 agtctcttgt tttggttaat actactgatt atatgtaggc aaatgtatat attatcggcg
     7081 acctgcccaa cttttttatg tggaatcgct tattttccct aattttgtat ccctaaaacg
     7141 gatgaatgtg gaagagtatt tgaatcaact gaatgagagc cagcgggaag cggtggttta
     7201 caatgagggg ccatccttgg tcgtggccgg ggctggctcc ggtaagacaa gggtactgac
     7261 ctataagatc gcttatttat tgcaattggg attgcctccc tatagtatct tggcgctgac
     7321 ctttaccaat aaggcggccc gggagatgaa agagcgtatt gcggccatca ccggtgacca
     7381 aacggcccgt cggctatgga tgggaacgtt ccattccatc ttctcccgta ttttacggaa
     7441 cgaggcggag catatcggtt atccttccaa tttcacgatt tatgacgcca ctgattccaa
     7501 gagcttactg aaatccatca tcaaggaaat gcaattggac gataaggtgt accgcctagg
     7561 aatggtgcag agccggatct ccaacgcgaa gaactccttg ataacttata cggcctacga
     7621 gcaaaataaa gagctcgtgg aaagcgatat gaacgccaag gtccccttgc tccgggaaat
     7681 ctacaaacgt taccagagcc gttgcctgca agcgggagcg atggatttcg acgacttgtt
     7741 gctgcaaacc aatatcctgt tccgggatca tccggccgtc ttggagaaat accggaactt
     7801 cttccggtat gtattggtgg atgagtatca agatacgaac ttcgcccaac acttgatcgt
     7861 gcaacggctt tgcgagagac acggccatat ctgcgtggta ggggatgacg cccagagcat
     7921 ctattccttc cgaggcgcta atatagataa tatcctgcaa ttcaagaatc tttataccgg
     7981 ttgccgtatc ttcaagctgg aacggaatta ccgttccacc cagaatatcg tgaacgctgc
     8041 caatagcttg atcgacaaga atacacgtca gatacccaaa acggtctatt ccgagaagga
     8101 ggcgggcaac aaggtgagtg ttttcacctc gtactccgat tatgaggagg gctacaccgt
     8161 agcagcccga atcaacgaga tgcacgggat attagggaaa ttctcgtatg ctgatttcgc
     8221 tatcttgtat cgtaccaacg cccagtcccg tatcttggaa gaggcgttgc gaaagcgggg
     8281 catcccttac aagatttacg gcggtttgtc tttttaccag cggaaagaga tcaaggacgt
     8341 gatctcttac ttccgcatga tcgtgaaccc gcacgacgag gaggccttga agcgaatcat
     8401 caattatccc acccggggaa tcggggatac gacggtaggt aagcttgttg gcgccgctac
     8461 tgaatacggg gtaagtctat ggaccgtgct tcaagccccc ttggaatatt cgctaccgat
     8521 aaataatggt acagctaaga aactgagcga tttccgtagt ttgattgaag ttttcattga
     8581 agagaataaa aaactctccg cagaggaatt ggctaccttg gtggtgaagc gtagcggcat
     8641 cgtttccgac ctgtttcaag accgttccgt agagggcgtg agcaagcaag agaacttgca
     8701 ggagttgctg aaaggtatcg ctgagttttg cgagatccgg cgtgaggagg gcatggagca
     8761 agtcgccatg tccgacttct tggcggaggt atccttgctc accgatcaag ataacgataa
     8821 agaggaaaac tccgataagg tcacgatgat gaccgtacat gccgccaagg gattggaatt
     8881 cacgaatgtt ttcgtggtag gcttggagga agacctattc ccctcgtccc tgtcgaaaga
     8941 taacccgaga gcggtagagg aggagcgtcg tttgttctac gtggcgatta cccgtgcgga
     9001 gcaaaattgc gtattgagct atgcgaagag ccgctatcgt aatgggaaga cggatatgtg
     9061 tacgcccagc cgtttcttga aggatataga cgctaagtat ctggatatgc cttcggatgc
     9121 cggcgcttca gatgcattcg cctcggcccg tgaacgctac gggcgcccgg cttttgcctc
     9181 tccattccgg caaccaaggg cggttgagga tgatttcgtg tcgccggtga agcaagcggc
     9241 acagcgtcaa gggcatctta cgaagctaaa aaacacgatg gaatcgtcct tttcggcggc
     9301 tccagccacg gatctatcgg ggttacatgt gggttccaag gttcgccatg atcgttttgg
     9361 ggaaggtgag attgtctcga tagaaggaga gggtggtaac gcgaaggcta cagtggcctt
     9421 cgatcatttc ggacaaaagc agttactttt gaagttcgct aaacttacta tgttgaatga
     9481 ttgacggtta gcttatggca tgtctgggca tgctacgagc cgcatcgtat ttcgcaccgc
     9541 atttcgcact acgtttcgaa tgaccaaggt gttggttttt agttgattga atgaaaaagg
     9601 tatcgctttt tcgcactgcg tttcgcacta ctatatataa gtatattagg aaagataaga
     9661 aaaaaagaag aggcgacgtc acgtcgccgt tttttccctt taaaacacac aatagtgttc
     9721 acggttgaat acaataatgt tcgccgccaa acacaatagt gttcgtggct aaacacaata
     9781 gtctttaaat gaaaaatata gttgtatttt tattgctttt tcggagcgga aaccttgctt
     9841 tctccgaatg ttttcgctat atttgcatat ttattatgaa atattgagat acagcatgat
     9901 agacatcaac aagataccct cgccttgcta tgtgatggag gagaaattac tgagaaacaa
     9961 cctgtccttg atcaagagcg taaaagaacg tgcgggagtg aatatcatat tggcttttaa
    10021 ggctttcgct ttatggaaag cgttcccaat cgtacgtgag tacattcctt tttcgacagc
    10081 gagctctaaa ttcgaggccc agttggcctt cgaggagatg ggaagtccgg cgcataccta
    10141 ttccccggct tatacggagg ctgatttccc gttgatcttg agatacagta gtcatgtcac
    10201 gttcaactcg ctctctcagt tccatcgttt ttatccgatg gtgcgggcgg atggtaaccg
    10261 ggtgtcttgt ggattgcgga tcaatccgga atactcggac gtggagacgg acctgtataa
    10321 tccttgcgcc ccgggttccc ggatgggggt gaccggcgac ttgctgggag ataagctgcc
    10381 ggagggtatc gaggggctgc atttccatac cttgtgtgag tctacctcct atgatctgga
    10441 gcggacactg gccgaggtgg agaggcgttt cggccgtttc ctgcctcacg tcaagtggct
    10501 gaatatggga ggcggccatc tgatgacccg taagggctac gacgtggagc atttaatcgc
    10561 tttgctgaaa ggctttaagg aaagatatcc gaacttggag ttgatcatgg agccgggtag
    10621 cgccttcgct tggcagaccg ggttcttgct gacaaccgtg gtggacatcg tggagaacca
    10681 cggtatcaag acggcgatta tcgacgcctc gttcacctgc catatgccgg attgcctgga
    10741 gatgccctac aagccggcta tccgtttcgc cacggatgcc gtggagggga aacctacgta
    10801 ccggatcggg gggaatagct gtttaagcgg tgattatatg ggggattggt cgttcgacaa
    10861 gcctttggag atcggcgaca agctgatttt cgaggatatg atccactaca cgatcgtgaa
    10921 aacgaatatg ttcaacggca tcccgcatcc ttccttagcc ctttggagca aggacgacca
    10981 gctggtgatg taccgtacgt tcggccatga ggattataag aacaggatgg attaaaaaca
    11041 agcaaaggga ggaatatgac catgacagcg aatgagttga aatatacata catggaggaa
    11101 gccatgagta tcttggataa tgaggagctt atgcgtaagg ctttatcgct cttgcggaac
    11161 ttaaaagaga agaccttctc gcctgccaag cgaagcgagc gggaggtgct ggaagaggct
    11221 ttccagagcg taaaagactt gaaggcggga aaaataacct ctcgcccatt ggaggatcta
    11281 ttgaatgagt tataagattg aggcattacc gcccttcgct aaggaggtga aatatttggc
    11341 gaaacgatat aagtcgttga aagaagatat cctaaggttg agggacgaac tgctggagaa
    11401 ccctttgtcg ggaacggatt tgggaggtgg cctccgtaag gtccggatgt ccatccgttc
    11461 gaaatcacag ggtaagagag ggggagctcg ggtgataact tttacggtac ttgtcagcgt
    11521 tgatgaagga acaatttatc ttgtgacgat gtatgataag agcgagattg agtctatgtc
    11581 cgttaaggag atccggaaac tacttgataa gtgtgatttg aagtaaataa aaacagaaac
    11641 aaaataaata tgggtatttt tagctttttc agtaaggaca agaaggaaac cttggataaa
    11701 ggtctgtcga agacgaagga gagtgttttt tccaagatta ccaaggcgat cgccggtaag
    11761 agtaaggtgg acgacgatgt gttggataat ttggaggaag tactgattac ctcggatgtc
    11821 ggtgtagata ccacgttgaa aatcatcgac cgtatcgaga agcgtgtggc ccgtgacaag
    11881 tatgtcacca cccaagaatt gaccaccctg ctgcgtgacg agatcgctag cttgctgaca
    11941 gagaacaata cggaggatgc cgagggattc gcgcttccgg agggcaagaa accctacgtg
    12001 atcatggttg taggcgtgaa cggggtgggt aagacgacca cgatcggtaa gctggcttac
    12061 cagttcaaga aagccggcaa gaaggtctat ctgggcgccg ccgatacgtt ccgtgccgcc
    12121 gccgtggagc aactagtgat ctggagcgag cgggtaggcg tacctatcgt gaagcagaac
    12181 atgggctcgg accccgcttc cgtggctttc gatacgctga gctccgccaa ggcgaacgat
    12241 gccgacgtgg tgattatcga tactgccgga cgtctgcata acaagatcaa cttgatgaac
    12301 gagcttacca agatcaagaa cgtgatgaaa aaggtgattc cggacgcccc ccacgagatc
    12361 ttgttggtat tggacggctc taccgggcag aacgctttcg agcaagcgaa acaatttacc
    12421 gccgccaccg aggtgaacgc cttggccgtg accaagttgg acggtaccgc caaggggggt
    12481 gtcgtgatcg gtatctccga ccatttccgt atccccgtga aatatatcgg actcggcgag
    12541 gggatggagg atttgcaagt attccgcaaa cgtgagtttg tcaattcgtt atttggagaa
    12601 tgagaaaaaa taaagtagat attattacgc tggggtgttc gaaaaaccta gtggactcgg
    12661 agcaacttat gcgccaattc gttgccaatg gctatacggt agagcatgat ccccataaga
    12721 tcaatggcga gatcgtggtg gtgaatacct gcggtttcat cggcgacgcc caagaggaat
    12781 cgatcaatat gatcctcgag ctgggcgagc aaaagcagaa aggacggatc gggaagctct
    12841 tcgtgatggg gtgcttgtcg gagcgtttct tgaaagatct ggagaaggaa cttcccgagg
    12901 tagatcgttt ctacgggaaa ttcaattgga aggagttgat ctccgatctg ggcaagtcgt
    12961 accatcaaga gctggctacc gagcgtgtgc tcaccacccc gaggcactac gcttacgtga
    13021 agattgggga gggatgcaac cgtacttgtt cttactgctc gatcccgatc ataaccgggg
    13081 cttatcaatc ccgtccgatg gacgagattg tagacgaggt tcgtggcttg gtggcgcaag
    13141 gcgtgaaaga attccaaatg atcgcccaag atcttacgtt ttatggcctc gatcgctata
    13201 agcgaatggc cttgccggaa ctggtggagc gggtatccga catcccgggc gtggagtgga
    13261 ttcgtttgca ttacgggtat ccgtctcatt tcccctatga cctgttgccg gtgatgcgtg
    13321 agcgtgataa cgtttgcaag tatatggaca tcgccctcca gcatatcagc gacccgatgt
    13381 tgaagatgat gcgccgcaat atcacgaagg ccgagaccta tgagctgttg gagcgtatgc
    13441 gccgggaagt gccgggcatc catctacgca ccaccttgat ggtgggtcat cccggcgaga
    13501 cggaacagga tttcgaggag ttgatccgct tcgtgaaaga tatccgtttc gagcgcatgg
    13561 gcgctttcgc ctatagccac gaggagggta cctacgccta tcagcattat aaagacgaga
    13621 ttccacagga ggtgaagcaa gaccggctgg attacttgat gcgtgtgcaa gaaggcatct
    13681 ccgccgacgt gaacgcctcg aaagtagggc agacctttcg ggtgatcgta gaccgggagg
    13741 aggaggattt ctacgtggga cgtacgcaat acgactcgcc cgaggtagat ccggaaatat
    13801 tgatctccaa ggatactccc ttgagtccgg gtagctttta ccaagtaaag gtgattgacg
    13861 cacaagcgtt tgatctgtat ggtaaagtgt tgaattgatg taaaaactgt caatatattt
    13921 gtcggttaac gaaaaaataa ctaatatagc agcacgaact gttatggaat tagatatgaa
    13981 aaacaaggag cttataacgg aattggcgaa tcgcatggat tggacctcga aggaggtatc
    14041 cgacatgctt tctgcgctca gttccgtcgt aagttcgaaa ttagtggata acgatacgat
    14101 ctatctgcaa ggcttcggcc agttcgaggt gaaaaagaaa gcggaacgta tttccgtgaa
    14161 tccggcgaac gggaagcgat atctggttcc ccctaaatta gttcccgtgt tcaagcccgg
    14221 aacgaccgtg aagaatcgtt taaaggaatt gggtgatcat gaataaccgg ctgaatatac
    14281 aagatttagc cggtttatta tcggagcgta ccggcaagga cagaggagag gtagagcgct
    14341 tcttgagaga ttttatctcg gtggtatccg aaggggtcta tacggataag atcgtaaaag
    14401 taaagggctt gggtactttc aagattatct ctgtggagaa gcgggagagt atccacgtga
    14461 ataccggtga acgtttcttg atccccgaac attataaatt ctctttcctg ccggataaag
    14521 acctgcggga acaggtaaac aagcctttct ctatctttga gacgacagag atcaacgaga
    14581 acgtggattt ctcggacatg gatgagtccg tagaggagaa ggaagcggaa gacgagtccg
    14641 tggaggaggt aatgccggat aaggaaatcc ctttggcaaa tactcagccc aaagagaagc
    14701 ccgaaccgat actagaacct gaacctgaac cattgcctga gccagagcaa gcgtttgatc
    14761 cggagccgtc atcggtatct gaaccggaac gtggattgga accggaactg cccgcggagc
    14821 catctcccat accagagaga ccggaagagc aagcccgtag gaaaccggag gaaaaggggg
    14881 tattaatgat cgtcgccttt ttgataatcg taatctctgt attcttctat ctgggaagaa
    14941 ataattggaa accggcgcct gcccaagaag aggtgataac ggaagccaag aatacggcca
    15001 aggacacggt tcaagaatca gcttggatgc ttcatccgga ctcggtagcg gagaagaccc
    15061 cgcatacgga accggagcct tatgtggaac cggcgccaaa accattgggg caggtgaaga
    15121 tcaagcatgg cgaccgcctc accgtgatcg ccttggaata ttatggcaat aaattattct
    15181 gggtgtatat ttaccaacat aataaggctg ttataaaaga cccgaacaac gtcccgatcg
    15241 gtaccgtgat cgagataccc gcaccggaat cgtatggcat cgatgccaag agccgtgagt
    15301 cgcgggagaa agccgccgcc ctacaaacag agatacttgc cggggagtaa gagaaatccc
    15361 ccttttttaa gtaaaataaa acaaaacgag gaagtgttgg ttagtattat ttaactgcaa
    15421 aagtgaagga tacgaattta acatttctaa ttttgtgcat cctaaaaaat caacgtaaaa
    15481 ttgggacaat ataataacaa tataatagaa taaatcttat gagtcagaca gtagacattc
    15541 gtgagttgaa tgagcgaatt gaaagtaaaa gctcgtttgt gaacatgatt acgatgggta
    15601 tggacaaagt aatcgtcgga caaaagcatt tggttgaatc cttgttgatc ggtttgcttt
    15661 cggacggaca tatcctgttg gaaggtgtgc cgggtttggc taagacactt gccattaaaa
    15721 cattgtcgtc gttgatcgac gctaaataca gccgaatcca gttcaccccg gacttacttc
    15781 cggccgatgt gatcggtacg atgatttaca gtcagaaaag cgaagagttc caggtaaagc
    15841 aaggcccgat cttcgctaat tttgtgttag cggacgagat caaccgtgcc ccggcgaaag
    15901 tacagagtgc cttgttggag gccatgcagg agcgtcaggt cacgatcagc gagcatacct
    15961 acaagttgcc gaagcctttc ttggtaatgg ctacccagaa cccgatcgag caggagggta
    16021 cgtacccgtt gcctgaggcg caggtagacc gtttcatgtt gaaggtgatc atcaattacc
    16081 cgaagaagga ggaggagaaa ctgatcatac gccagaatat atccggagaa cgtccggaga
    16141 tcaagccgat cttaacgaaa gaggagatcc tcgacgcccg taacgtggtt cgtgaggttt
    16201 atttggacga gaagatcgag cgttacatcg tggatatcgt cttcgctacc cgtttcccgg
    16261 ctgaggctgg tttgccgaac ttggcgagca tgatctcttt cggcgcttcc cctcgtgcgt
    16321 ctatcaactt ggcgttggcc gcccgtgcgt acgctttcat caagcgcagg ggctatgtga
    16381 tcccggagga tatccgtgcg gtatgccacg acgtgatgcg ccatcgtatc ggcttgagtt
    16441 atgaggccga ggcgaacaac ttgacttctg aggaggtaat tagcgagata ttgaataaag
    16501 tagaagttcc ttaaatggag acaagcgaat tattaaagaa ggtacgccgt atcgagataa
    16561 agacccgtgg tctttcccgt aacatcttcg ccggccagta ccattcggct ttcaagggcc
    16621 gtggtatggc gttcagcgag gtaagggaat atcaatacgg cgatgatatc cgggatatcg
    16681 actggaacgt caccgcccgc tacgtccgcc cctacgtcaa ggtgttcgag gaggagcgtg
    16741 agctgacggt gatgctgctg atcgacgtgt ccggtagccg tgactttggc tccgtcaacg
    16801 tcatgaagaa ggaggtgatc accgagatcg ccgctacctt ggctttctcg gcgatacaga
    16861 acaacgataa gatcggcgtg gtgttcttct cggacaagat cgagaagttt atcccgcccc
    16921 agaaaggaaa gaaacatatc ttatatatta tccgggagct gatcgatttc catccggagg
    16981 agacgaggac ggatatcagc caagtgttga aatacttgac caacgccatc aagaagcgtt
    17041 gcacggcttt cctcatctcc gattttattg acaaggaggg tttcaaggac gccttgacgg
    17101 tggccaaccg caagcatgac atggtagcca ttcaggtgta cgaccgtcgt gagaccgagc
    17161 ttcccgccgt aggccttatg aagatcaagg acgccgagac cgggaaggag caatggatag
    17221 acagttcctc cgcccgtgtg cgtgcggcct ataaggaatg gtgggagaaa cggcaggcga
    17281 agatgagcga tacgttcaag aaatgccgtg tagactccgt ctctgtccgt accgaggatg
    17341 attatgtgaa agcattgatt gctctttttg acaaacgtaa ttaaagcaag cagatgaaat
    17401 tgataaagaa aagtatcctg tttctggtcg ccgccgcttc ccttgcgggg ggaagggcat
    17461 atgcgcaaag gccgttgatc gatgtcgcta tagactcggc cgccatattg atcggagagc
    17521 agactacctt gcaccttacg gtaacggcgg ataaggatcg ccccgtgcag atcgtgatcc
    17581 cgaacgatac cttgatgacg ggtgtggagg tactgaatct ctccaaggcg gactctacgg
    17641 agatcgagaa cgaccggctc gttatcaagc aggatgtatt gattacctcg tttgattcgt
    17701 cactctatct gttacctccg ttgaaggtga tagacggggt ggataccgta tattccaacc
    17761 aagtcgcctt gaaggtctcc acgattcccg tgaacgcaga caagccggag gagttcaacg
    17821 acatcaagac cgtatggaag ccgcctttcg tatgggccga ttattatccg atcatttacg
    17881 ggatcttgct ggccctgttc ttgatttgcg tgatcgccta tatcgtgaaa cggatccgtg
    17941 cgaagaagtc gttgatacca ttcaagaaag aggagccgaa gctcccgcct cacgagcagg
    18001 ccatcaagga actggacgag atcaagcaac agaaactctg gcagcaagga cgaagcaagg
    18061 agtattacac cttgatcacg gatacgctgc gtaagtatat cgaggaacgt ttcggtatca
    18121 atgccatgga gatgacttcc ggtgagatct tggacctgat ccgcaagaac tccgaggcgc
    18181 agagcgtgta cgaaaacttg aggcagattc tgcaattggc cgacttcgtg aaattcgcca
    18241 agatgaaccc gctgccggat gagaatgatt tgagtatgat gaacgcgtat ttgttcgtga
    18301 accagacgaa ggaggaggag atggtggagc tggttgacag tcccctgtca gatgagctga
    18361 cagcctcggg tcaagaggag cgacagcctg ctgtcaaagc cgttgacagc cctctgtcaa
    18421 atgagccggt agccccgtgt caagacgact tgacacgcta tcagcccaag tctacgaacg
    18481 atacaactaa tttaaaggat taagagatgg tatttgcgaa tcctaattat ttatatttat
    18541 tgttgttgct cattccgatg atcggatggt acgtctacaa gctgagcaag agtcaggcca
    18601 gcttgcaggt ctcctcgtcg gaggcgttcg aggcgccggg agcgacatca tggatcgtgt
    18661 acttgcgtca cgtgcctttc gtgttgcgta tggtagcggt agcgttgctg atcgtgatct
    18721 tggcccgtcc gcaatccacg aatagttggt ctaattcttc cacggaaggt atcgatatca
    18781 tgttggcgat ggatatctcg ggtagtatgc tggcgcaaga cttgaaaccg aaccgcttgg
    18841 aggcggcgaa ggatgtggcc gcgtcgttca tcaacggccg tccgaacgat aacatcggtc
    18901 tcgtggtctt ttctgccgag agctttacgc aatgcccgtt gacaaccgat catacggtct
    18961 tgctgaatct tttcaaggat atccaaagcg gtatgatcca agacggaacg gctatcgggt
    19021 tgggcttggc gaatgccgtg agccgtatta aggacagcca cgctaagtcg aaggtgatta
    19081 tccttctgac cgatggttcg aacaacgccg gcgagatcgc tccggttacc gccgctgaga
    19141 tcgccaagac gttcggcgtg cgtgtctata cgatcggagt cggaacgaaa ggcatggcgc
    19201 cgtatccgtt ccagaccgct ttcggcgtgc agtaccagaa tataccggta gagatcgacg
    19261 aggctacgtt gaagcagatc gcctctacca cgggcgggca atatttccgt gctacggaca
    19321 acgccagcct gaaggagatc tattccgaga tcgaccagat ggagaagacc aagatcagcg
    19381 tacaggagta cagcaagaag caggaggagt ataagaactg ggccttgctg gtgttcgcct
    19441 tgttgctggt ggagatctta ttgagaaata cattgttgag aaatatacca taaagataaa
    19501 aggcttatgt ttcgatttgc gcatccggac tttttatatt tgctttttct ccttccggcg
    19561 ttggtggcgt tctacgtgta cgccatgatc gtgaagaaga aagcgataaa gaaatacggt
    19621 aaccctacgt tgttggccga gttgatgccc gaggtatcga ccaagcgcca gcatctgaag
    19681 ttttggctgt tgttcggagc cattaccatg gttatcttta ttatagcggg gcctcaattc
    19741 ggctcgaaac tggagacggt gaagcgtcag ggagtagaga tcatggtgtg tctggacgta
    19801 tccaactcca tgttggccga ggacgtgtcg cccaaccgtt tggataaagc caaacagatg
    19861 ctatcccgat tgacggacgg ctttacgaat gataaggtag gtttgatcgt gttcgccggc
    19921 gacgctttca cgcagttgcc gatcacctcg gattatatct ccgccaagat gttcttgtcc
    19981 tctatcaacc cgtcgatggt ctctacgcaa ggtacggcga tcggtgccgc catcaacttg
    20041 gccgcccgtt cctttacccc ggacgagacg accgataagg cgatcatctt gatcaccgac
    20101 ggcgagaacc atgaggacga cgctatcggt gccgccaaag ccgccgccga gaagggcatc
    20161 cacgtgaaca tcgtgggaat gggtgatccg aaaggttctc cgatccccat ccaaggaagc
    20221 aataattata tgaaggataa ggatggaaac gtggtgatca cgaagctgaa cgagcagatg
    20281 ggtcaagaga tcgccgccgc cggaaacggt atgtacgtac gtgcggacaa tacgaactcc
    20341 gccttgaaag cccttcagaa ggaaatcgag aaaatgaata agacggagct ggatagcaag
    20401 gtttattctg agtatgacga gcagttccag attttcgctt ggatcgcctt atttctcttg
    20461 atcgccgatt tcatgacctt ggatcgtaag aaccgtatat ttaggaaagt aaaattattc
    20521 tccttaattc tttttctctg cgccgggacg gtctctgccc agaaagcgga acggaagaac
    20581 gtgcgtgagg ggaataaact ttacgagagc gagaaataca ccgagtccga gatcgcttat
    20641 cgcaagagct tggaggtgaa tccccgctct acggaaggaa cctataatct gggaaactcc
    20701 ctatacaagc aaggcaagtt ccccgaggcc gccgagcaat atcaattgat cgccgggcaa
    20761 ggggagaaga tggtggctac gccggaaggg aaggcacgct tgtcggaggt gtatcataac
    20821 atgggaaata tcttcatgca gaacaaggat tacggcaagg ccgtggaggt gtataagcaa
    20881 tcgcttcgct tgaacccgaa agatgacgag acccgttata acttggcctt ggcccaaaaa
    20941 ctgctgtcgg atcagcagaa tcaggatcag agccaagatc aacagaacga cgacaagcag
    21001 gagaacaagg atcagaagga cgatcagcag caacagcaac aacaacagcc gcaagacgac
    21061 cagaagcagg ataagaccca agagcaacag caacagggcg agcaaatgag caaggacaat
    21121 gcccagcaga tgttggacgc cttcctgcaa gacgagaaag acactcaaga gaaggtgaag
    21181 aaggcgcaga tgcagcagca acaacgccgg aagaccgaga aggagtggta aactggataa
    21241 ttaacgaaaa aatgagatac acaatgagga aattaatttt cttattcatc ctgatgttaa
    21301 cggtaggggg ggcgacaaag gccgcggatg tgaccttcaa ggcctcggcg ccccaagcgg
    21361 tggtaatggg agagcagttt cgcttaactt tcactgtcaa tgccgaaggc aaggatttga
    21421 gagtgcagga gatgccagac tttgacgtat taatgggtcc ctcccaatcc acctcctata
    21481 gcagtagctg ggtgaacggg aagagtacca gcgagacaac cgttacgtat acgtatgtct
    21541 tgatgccgaa gaaggaaggt acgtttaata tagctccggc aacgatcaag gtgaacggct
    21601 ctaattatac atcgaatggc ttggccatca aggtgcttcc ggcggataag gcgggtaagc
    21661 aagaggcgga gacaacgacg gcgagcgggg cgatctctaa cgatcggctg ttcgtgaaga
    21721 tggacgtatc caaacgaagc gtgttcgagc aagaaggttt cttggtgact ttcaaggtct
    21781 attccttgga aaatttctcg attacgggat tgaaatatcc ggagttcgag ggtttcttgg
    21841 tacaagaggt tgagttgccg caagagaaac aactgacctt ggaaaactac aacggacgta
    21901 actaccagtc ggccgtgatg cgtcaagtga tcctgtatcc ccaacgttcc ggtaagatca
    21961 cgatcgaagg tggaaagtat gatgccgtgg tgcgtgtccg tatgcaacaa gcgggcggcg
    22021 gtagcatctt cgatagcttc ttcgactcgt atcgggatgt gagcaaggtg ttgaccacct
    22081 ctccggttac tatcgacgtg aagcctttgc cctccggtaa gcccgcttct ttctccggtg
    22141 ccgtaggtac gttctccatg acggctgata tcagctcgaa caacgtcaag acagacgagg
    22201 ctgtaaccat aaaggtgaaa atcacgggta acggaaacgt gaagttggtg aagaacccgg
    22261 aagtggtttt cccgaacgat ttcgatgtct acgacccaaa agtagagatg gacatcaaga
    22321 ccacgactgc cggtgtcagt ggaagcaaga cgatcgaata tatggcgata ccccgttacg
    22381 cgggtgattt cgagatcccg gcgatcgctt tctcctattt cgatatcaag tccggttcct
    22441 ataagaccat caagtccgag ccttataagt tgcatgtgga gcaaggcaag ggtggtagtg
    22501 gttcttcccc ggtcgtatcg aacttcagta ataaagagag cgtgaaatac ttaggcaagg
    22561 atatccgtta cctaaagacg aaaggcttct cctttataga gggaggtgat ggtatattct
    22621 tcggttcctt tatgtattat ctttgctata tcgtaccggc tatcttgttt atcgtattct
    22681 tctttattta tcgtaagcag gtgaaggaaa acgccgacat cgccttggtt cgtaccaaga
    22741 aggcgaacaa gatggcggtt agacgtctga agaacgccgg caagctgatg aaagagaaca
    22801 agaaggaaga attctacgac gaggtactgc gtgcgttgtg gggctatttg agcgataagc
    22861 tgagtatccc gcaatccgat ctgaccaagg ataacgtaga gacagaattg gctaaatacg
    22921 gtgtagacga atccttgacg aatgagttca tggatatctt gaatacttgt gagttcgctc
    22981 gttacgctcc gtcccaagcg tcagacgcta tggataagct gtatgagctg acggtagacg
    23041 ctattggtaa aatggagaat acaattaaaa agtaagaaga tgaagatgac tataaattta
    23101 agaaaggtgt tgtttttctt attgactcta tgtctgatag gatctgctta tgcgcaagat
    23161 accgccttga aggaggccga ggtcgcttac acgaaagaag attatgcgaa ggcgatcgag
    23221 ctatatgagg gaatcttgaa gagcaatggc gagtctgccg ccgtttatta taatttggga
    23281 aatgcctatt ataaggcggg taagatcgct ccggctatat tgaactacga acgttgtctt
    23341 ctgctggatc cgggtgatag cgatgctcgc ttcaatttac agatggcccg tcagaagacg
    23401 atcgataaga ttgagccggt tggtgatttt ttcttggtca aatggtttaa gagcgtggag
    23461 aacctcggtt ccgcagactc ttgggcgaag actggtatcg tgtgcttcct gttgtttatc
    23521 ggttgcttga tcttgttctt tttctcccgt tgggtacgct tgaagaagat cggtttctat
    23581 ttgggtgtcc tatttattat catggttgtt tttgccaata tattcgccag cgaccagaag
    23641 gatgagatga taaaccgtaa acacgctatc gtattcgccc cgaccgttac ggtgaaaagc
    23701 tcgcctgacg ctagcggtac ggatcttttc gtattacacg agggaacgaa cgtgaccgtg
    23761 aagagcacgc tcggcgaatg gagcgagatc gagcttgagg acgggaacgt aggatggatg
    23821 cctagtaaag acatagaaaa aatctgatac atgctagaac aattattggt ttgggaacgt
    23881 gatgcgttct ttatgcttaa cggtagcgac tccgcttttt tagatcgctt tatgtggatc
    23941 tattcaggca aggcggtttg gctaccgtta gcctttttta tattggtggt attgtgctat
    24001 aagaagaact ggaaggagtg gttgttgatc ttattggcca ttgtcttgac gatcacgtta
    24061 tgcgaccagt tcgcttcgca tgtttgtaaa cccatcttca cccgtttccg tccgactcat
    24121 caccctgact ttatggatca ggtaagggtg gtgttcggtt atcggggcgg tatgtatgga
    24181 tttatctcca gccatgcggc gaatgctttc ggctttgcga ccttgatggc gctgatcttc
    24241 aggaataaac tattcggatg gactattttc ttttgggcga ttttgacttc ctatactcgt
    24301 atttatttag gagtgcattt tatcacggat attattccgg gagctttatc cggtctgcta
    24361 ttcgggtatc ttgtatatct gttataccac tatataaggc ctaaattgat tccggcagat
    24421 tcttgggtat gtccggaggc catttactcg gatatccgga aacgctggat cacctatgcg
    24481 atttggttga ccatcctttt aatagcccta tttaatgagc aattggtatc gtgcttaata
    24541 taagagattt tcgttaagta tgtcgtaaag catatttgtt ttcagctcat tttctcaata
    24601 ataatttgtt tcaatgctat taaatgacta agttagtgcc ataatattaa acaaaagtat
    24661 taaccttcaa aataagaaag ccatgacaaa gacgattaca tttaacgaac tgagaagaat
    24721 taaagattcg ttacctgacg gaagtacaca acgcatcgcc gatgagctgg gattaaaggt
    24781 agagacagtt cgtaactatt tcggtggaca taattttcaa gatggacgga gttgtggttt
    24841 ccatatcgag cccggtccgg acggagggtt ggttgtttta gatgacacga ctattttcga
    24901 gcgtgctttg cagatactgg ccgagagtca ggatgccgaa gcacaaaaag cgtaagagaa
    24961 attcattcgt ataaaaaatc ccatagctaa atgaaagaac gctttgggat ttttttatat
    25021 tcaacaattc ataaatcccg attgtttcat ctataaaaat gtattgagta tggaagataa
    25081 attagtgaca ttggctatcc acacgttcga gaaagcccag attctcaaga caatcctcga
    25141 aacagaaggc atagaggtct atatacataa tgtaaaccag attcagccgg tcgtttcggc
    25201 aggagtgcgt gtgcgtatta aggagagtga tttaccgcat gctttacgca ttattgaaga
    25261 caataagtgg tttgaggaac caaaggagga agaggcgaag gttaatgcgg tcaagaaagt
    25321 tctgatcccg attgatttct cggattattc cgccaaggct tgtgagttgg gaattaatta
    25381 cgctcatgcg gtaggtgcgg aggtgatgat catgcacgcc tatttcagcc cctattttcc
    25441 atccgctatc ccgatgggag atactttggc ttaccaagta aacgaggagg aatccgtaca
    25501 gcatatctta caacgtgtcc gtatcgatat ggagaatatt tgtacgcata tcaaccggaa
    25561 gatgtcctct ggtgaattac caaaggtaaa atacgattat gtattacgtg aaggcttgcc
    25621 ggaagaggag atcatcgcct atagcaagga gtatcatccg acattgatcg tgatgggaac
    25681 gagaggtaag agccaaaaag atatggatct gatcggtagc gtgaccggag aggtaatcga
    25741 ggtaaaccgg gttcctgtat tggcgatacc ggagaatgtt cctttcacgg atttgagaga
    25801 cgctaagaat atcgctttcg ctacatcgtt taaccagaga gatttggttg cgtttgacga
    25861 gtttatggaa atcatcaaag gctttgatct taatatccat ctattcaata tctctaccag
    25921 taatgatgaa tggaatgaga ttcgtttaac gggcgttcgt gaatatttca aaaaacaata
    25981 tccacatgcc catatttccc atacggttct agccgatggt gacttgctgt tagccatcga
    26041 gaaatttgtt cgtgataaac aaattgatgt tatagcccta agcacatatc gccgtaatat
    26101 cctagcccgg atgttcaatc cttcgatcgc gagaaagatg ttattccaca ccgatactcc
    26161 gttattggta atcgatagca agaaatagct tcttattcaa gtaacaaata aaaagtggat
    26221 atgagaaaag gcttatccac ttttttatta tataccatgt gcttaaagca atctttgtat
    26281 ctttggcgaa aaaatataag gatagtatgt gggaaagaat gtttgatctg gtacttggat
    26341 taaagaaaga acatagatta atgatagtta taacattgat ttatgcggtg accctctttg
    26401 gtattactgt agatgtagaa gcgatggaga attggctgca attagtgggg tataccatac
    26461 gtactttatg tattgcttgt attatacagc ttagtgtgtt ctttttgaca aatatttttt
    26521 ggaaggaact aaacagaggc ttgaataaaa catttgttgt tattagtggt aatgtgttgt
    26581 ctttagcttt cttacttttc cctttttcta tatcatatat agatatgact gctgaaagta
    26641 tgaaattgag ttctttgaat acagaaagaa atagaattga tagtatggtc cggtactatg
    26701 agaatttaaa aagtctagat tcttcttttt cagagaatct agattcttta atattggaag
    26761 aaaagaaaac attgattcgg gttataaaag agattgactt aaagcaattt aaaatagaag
    26821 agaaacagaa aagatatgaa aagccattag tctccatcct atttcttttg caaatattcg
    26881 gtttttatat attgattcta tattcttcct attttgatag gacgaataag gtgaatcgtg
    26941 ttatcgcagt ggaaaatatt ccttatcgaa agaaagtaag gagctatttt tgcgataaag
    27001 ttttgaagcc tttggtttta ctgttatctg tttttctttg gggattcttg tttttccttt
    27061 ggcttagata atatatacct gatatttgta taaaccggaa tttatgcttt gctttgtggc
    27121 tcatcagaaa aataatagaa tatatgatta cttatttgat tattggaata acagtggttc
    27181 tctcttttat ctgttttagt aatagggagt tatttatgaa attagcgttt atcccatatc
    27241 gtacgatccg gaatcatgaa tattatcgta tcgtgacaca tggatttatc catgcggata
    27301 tgacacattt gctagtgaat atgttcacgt tctggtcatt tggtctctat attgaacgaa
    27361 cgtttcgata tatgggattc ggcagtgggg cttatctggc tttttatttc gggggaatga
    27421 tcgtggcttc gctttatgat ttgataaaac gacgtaatga tccgtattat gtctctatcg
    27481 gtgcgtctgg agcggtatcg gcggttctat ttacctctat attccttgat ccttggggaa
    27541 agatcttgtt tttcgccgtg ctgcctgtcc ccggaatcgt attcggcttg ctatatctgg
    27601 cctattgcca gtatatggcg aaacaaacag gagataacat aaatcataat gcccatttct
    27661 acggggctat ttatggattg attttcccaa tgctgctgga gccttcgtta ttgcatctct
    27721 ttttgtctca acttacgttt aagggatgat ccaccctgaa cggataattt aaggttattt
    27781 tttgtccgaa gattatttcc gggtaggtaa acttgtctat ctttgtcccc ttataagcaa
    27841 aagttagatg aacaaagata ataatttggg tagagtgtta gcgttactgt cgctgacgtt
    27901 gttgatgagc tttggtttat atagccttcc ggatacattg ttcgggtata agatcaaaaa
    27961 ggtagatctt ttatcggatt tcaaggtgaa agaggaaaag ctctccttgg attctttgaa
    28021 acaacaattg gaacaagcgg acacccttca agtagattcg gtagcattaa gggattctat
    28081 catgcgttcc gccggaatag attctgcggc tttggccctt cgtgattcgt tatacaaagc
    28141 ggtctatgct gttcaagggg cggattcgct gggggctcat atcgaggact attctcttgg
    28201 acatatcggt ttgcaacgat ttttcgccgc cttaaaaaac aggcgggaat tgaatcgtcc
    28261 ggtacgtgtg gccttccttg gagattcttt tatcgaagga gatattatgg tggccgattt
    28321 ccgttccggg atgcaaaagg aatttggggg gcggggtgtt ggttttgtac cggtcacatc
    28381 cgtagcggca cagttccgtc caaccgtgga gcaacgtgcc tccggatgga ctacttggtc
    28441 tatgctgaca gatcatgagc atggatatac tttatccggg atgatgttcg aggcaaacga
    28501 ggagaacgcc tctatccatg tgaagacgac taagcgttat ccggagctcc agacgttctc
    28561 ttctttgaaa ctgatttatg agcagaataa gaatacggag atgcgcttgg tttgcaacgc
    28621 ttccgccgat accctacaag agatgcttcc cgccacatcg atcgtaaccc aatacgagtt
    28681 ggaagggatg ttcaccgaag cggatttcac ttttaagaat actccggagt tccgggcatt
    28741 aggggtcgct atggaggatc attcaggtgt cgtggtcgat aatttctctc ttcggggaaa
    28801 ctcgggtatg atattggagc gattggatgt ctcccgttgc caagcattga ataagatccg
    28861 tccgtatgac ttgattgtct tgcagtatgg gttgaatgtc gtgagcgata gcgtgatgaa
    28921 ttatggatgg tatagtagcc ggatggtaaa ggtcattaac catatacaac tttgttttcc
    28981 ggaagctgat atattgatgt tgggggtgtc ggacagaagc cgtcaagacg atggcgaatt
    29041 cgagacgatg ccagccgtgt tagccttgct gcatgcgcaa aggcaagctg ctaaaaaggc
    29101 aggggttcct ttctggaatg tattcggtgc catgggagga gagaatagta tggtccgttt
    29161 cgtagaatta aactgggcta gtaaggatta tacgcattta agcttcaggg gtggacggga
    29221 gattgccgat gccttgctga aagcgttatt atcagaaaaa gatttttatg atgaagcgga
    29281 gaaagtggtt aattagtctg gttgttttag gagtgatcat gggcttctct gttccgaaac
    29341 ctaaagccgg aataaacggg gatgtatctc ttgatagttt ggcggttcgg gatactgtag
    29401 cgttgcctcc tttatcttat tctatgaaag tgggaaaaga tacgttgatc ttaccggatt
    29461 ctagtaaggc gtggaataat tttttcaatg aactggattc gttgcgtgca gggaaagata
    29521 cggctatcac gatcgtccag ttgggggatt cgcatatcca agccggacat ttaagcggtc
    29581 gtgtcatgcg ccttttccaa caggcgttcg ggaatgccgg acgaggctgg atcgctcctt
    29641 ttaagttgag caagaccaac gagccggatg attattttat caaatccgtc gctaaggatt
    29701 ggattgccgg acgttgtatt cagcatgtcc ggaaaacccc gatagggatc ggtgggatcg
    29761 ggattaagtc tgtttccccc tcgattaatc tggatgtcgt gataaccccg aataatggtg
    29821 ccggatacga gtttaatgag gcgatcttat atagagggga gaagtcgatg cccatgcttc
    29881 ctgccggggc tttgaaagac tcggtccaaa cattccgtgc ggataccgta tgtgttcccg
    29941 gtgtattagc cgacactttc cggatctcct gcttgaccga tactctacaa ttgcagagta
    30001 cgagacggaa agagggcacg aatacattgc gtccggcctc atcctttacg aatttatatt
    30061 atggcctgac actgaagaat ggaggcaggg gtatcttata ccattccatc ggagtgaatg
    30121 gggcaatgta tgtgaattat acggacgagg cttatgtacg tcagttggct ttattaaaac
    30181 cgtccttatt aatcatctct atgggaacca acgagacgtt tggcagacgt tttaataccg
    30241 atgagttttc cggtcagata gaggctttct tggcgttagt caagaaggag ttacctaata
    30301 cggcaatctt actgacgact cctccggaat gttataggag agtccggtcg ggtaaacagc
    30361 gaacgtatgt gcgtaatgat aataccgagc gggctgcccg tgctatccgg aatgtagcga
    30421 agaaagaaga ggtcgcttgc tgggatttat tcactacgac aggagggaaa aactcgtgcc
    30481 gcaaatggca tagttctcgt ttgatgggac gggatcggat tcactttacg aaagaagggt
    30541 atcaagaaca aggaacgctt ttgtttaggg cgttcatgga atcatataat aaccgataag
    30601 aattttatat ggaatataat atacttagag attggcttag taatcatcaa ttcacgtggg
    30661 agaaactggg agatatcctg acgtatcatc ataatgcccc gatcttgttt agtagcgggt
    30721 tgttcttctt cttgtttatc ggtttcctga tgatttatat gtcgctaagg aaacatacgt
    30781 tggctcgtat tatttatgtg acattgtttt ccctttattt ctattataaa agtagtggac
    30841 tttggttcgg gctgctggta tttacggcta cttccgattt cttgatagcg caatgtatct
    30901 cgcatacgac atcggtatta aaacgtaaat tattcgttac gcttagtctc tgcataaacc
    30961 taggtatgct ggggtatttc aagtatttca atttcctagg cgaactgttt actatggccg
    31021 ccgggggaga atggcttaag atgaacatct tccttccggt aggaatctct ttctttacct
    31081 tccagagtat aagctatgtg atagatgttt atcggggacg aatccaacct ctcggccgtt
    31141 ggatcgatta tgttttctat gtatcgttct ttcctcaact ggttgccggg ccaatcgttc
    31201 gtgcccggga ttttatccct caaatgtata agaatcctac ggtgacgcga tctgagtttg
    31261 gtgagggatt gttccttatc ttatgtggtc ttttcaagaa aacggttatc tcggattata
    31321 tcagtatgaa tttcgtggat cgtatttttg acgctccgtt gctttatacg ggtgtggaga
    31381 atttattggg tgtctatggg tatgcgctac agatttattg tgacttctcg ggttattcgg
    31441 atatggcgat cggtatcgct ctgttgttgg gattccgctt taatataaac ttcgactctc
    31501 cctatcaatc ggctacgatt accgagtttt ggcgtcgttg gcatatctcc ctttcctctt
    31561 ggttaaaaga ttatctgtat atatccttag gggggaaccg gaaggggaag attcgtacct
    31621 atatgaatct gatgataacg atgttgctag gcgggttatg gcatggggct tccattagtt
    31681 tcatcttatg gggagcctta catggtatag ctttggctgc gcataagttc attatggggc
    31741 atttcagtag ctttaaggcc ttaggatgcg agatgaaacc ttggcgacgg gtattaggtg
    31801 tcctgattac tttccatgtg gtttgtttcg gatggatctt gttccgagct acctcgatga
    31861 aagccgtggg agagatgctg agccagatct tcacgaattt tcatccggag gtgttcatgc
    31921 aattcgtctc aggatataaa ggggtgttcg cgttgatggt gatcggttat gtgctgcatt
    31981 ttatgcctaa acgctctgag gatgtcttga gggaaatcgt gactcgttcc cctttattga
    32041 tacaggccgc tatattggcg atagcgattt tcattgttgt tcagtttaag ag
//
LOCUS       DBMDTB010000037        31776 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_552_length_31776_cov_11.519463, whole genome shotgun sequence.
ACCESSION   DBMDTB010000037 DBMDTB010000000
VERSION     DBMDTB010000037.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 31776)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 31776)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31776
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_552_length_31776_cov_11.519463"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(397..2103)
                     /locus_tag="ACZPB4_07880"
     CDS             complement(397..2103)
                     /locus_tag="ACZPB4_07880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RagB/SusD family nutrient uptake outer membrane
                     protein"
                     /protein_id="HIR1098175.1"
                     /translation="MKISKITNWMVAGAACLLLGTSCDVDPTFYSQVVPDTYYTNADA
                     IWSRFNRPFTHWRWWVAHNDARVRLMEVGTDAMCVPTRGNDWFDGAVYQNMHHHHFMD
                     DMSPMKDGWDLTTMGVAQSWSALEDLENIDFVSVGLTEEDRVSMINQLNVLAASFYLD
                     GLDMFGGMPLYTSTKEDVKARATDVETFHFIDSLLDVSMPNLPLKETLGAPETNVIHR
                     AVAAALKVRLYFNAESYINKPMYEEAAKICQDIIDGKYGQYKLANHFTEIFGWGNETC
                     PEIIWTVPSENAKGETDGGLTAFTLPYNFKDFLGGLQDASGNNGLCLCPSRDPEGNLY
                     KFNVGNPYETFNDKDIRKQQYVYEGGRKYRGMFIVGELQNPDFPEYKCLGAREYAGKV
                     LNVVDQIAHISQVGNTVASLKDLTSTIADAEENSGVRVLKFSPLPNQDEFKERFNPDC
                     PVIRLTEIYYTLAECKMRLGDKNGAADIINSIRKRNFEGGNDPDPVTAANLDKYRMLK
                     EWMQEFLREARRRTDLIRWDAYVTEDWWDHKATNDEKYNRYPLHQLSLGANPLLEQNP
                     GY"
     gene            complement(2120..5182)
                     /locus_tag="ACZPB4_07885"
     CDS             complement(2120..5182)
                     /locus_tag="ACZPB4_07885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SusC/RagA family TonB-linked outer membrane
                     protein"
                     /protein_id="HIR1098176.1"
                     /translation="MEKCSKKSKQLCLSLFKPSVMMLTTGFLCMASFQGLAAVEPSHN
                     YGPNVESVMQNGKTITVKVSDSMGELIGANVLVKGTTIGNVTDMNGSVTLQDVPANAV
                     LEISYIGYTTKEVPVGSQSVINVTLSEDSQALEEVVVVGYGTMEKKQVTSSVTSLSAG
                     DMMKGVGGADITSSLQGKISGLILQNNGSANGTTTIQLRGLTSINSGKAPLIVVDGFP
                     GGDIRALNQDDIKSIDVLKDASAGAIYGTRAASGVILITTKSGSNTNGKVKLNYSTEL
                     SKKQNYGRPDMMTADEYRNRTDVNITDYGQNADWWDALLQKDNFSQKHHLSLELGTEN
                     AQVYTSFFYETNEGITIKDNRKDYGGRLNANFKLFDGWLEIRPIVDYRQTARTSDGSD
                     EDKKANFKQALYNNPTRSPFDPESPTGYNVWTGETLDYNIVADRMLTDYEGLDKWFKP
                     EVTMKLNIKPIEGLSYSQTLGYENRQWELHQFRSRYHRDEVTNNRGGWAKLEFSKTEH
                     LTSEGYFTYLKEFKGGHSLNAVAGYSYFEKNGENFNAENYDFGVEGLKYWDLGAGSYL
                     TDGKAAMGSGKNITERLFALYARANYSYNDKYMVSATIRHEGSSKFAAENRWGNFWAL
                     SGGWRVSAEEFMKEFDWVSDLKVRFGYGVTGNNDFDASYMANTLSRDQYWMLPSGSWA
                     YVYGPSSNVNPYLGWEEKKEWNIGVDYSFFGNRMYGKFDYYRRKIDGMIYEVNVPQPP
                     YPNGKQWQNIGEMESKGWEFEVGGDIIQNKDFTWTSSLNMSHNSGKILTMYGNNSRMD
                     GNAMDEPGWPGDAARIEEGAEIGAFHMWKFAGFDDKGDFLLYNKDGEVIPASQKSVDD
                     KQYIGNYLPKVMMGWNNTFTYKNFDLGINMRSWIGFDVLNTYPMYLGIQGQSGAGQWN
                     LWKPALDDPKFKDIRGVKQLCDYFLEDGSFLKIDAITLGYTLALNKYTKWAERLRVYG
                     TVGNVATITGYSGHNPEVDITGWTGGTDKVWNCDPIVRTYTLGIQVTF"
     gene            5556..6407
                     /locus_tag="ACZPB4_07890"
     CDS             5556..6407
                     /locus_tag="ACZPB4_07890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HIR1098177.1"
                     /translation="MKLQIIDTGYFYADGGAMFGAIPKSAWSRRYPSDETNGCVLAMR
                     SLVIKTDDGRIVLVDNGAGNKHLKQLSYYRFFNLVDLGTELRNRGIQPEEITDVVLTH
                     LHFDHCGYTTQKDESTGHLFLSFPNANHWVSRKQWENFLHPNALERDSYFIENMQAVA
                     DANSLRLLDADTSICPTIELRLYDGHTPGQIVPYIHTEDRTFVFAGDVIPLVASVSPE
                     WISAYDTYPITSYNEKLRMLAEAAEKRQALIYCHDAYIRCTTVKRVNSYYKKDKEIPL
                     KKTFLFP"
     gene            6703..9024
                     /locus_tag="ACZPB4_07895"
     CDS             6703..9024
                     /locus_tag="ACZPB4_07895"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 20 protein"
                     /protein_id="HIR1098178.1"
                     /translation="MNSLSKLALVLTFCTGMIACSGGKAVKGDYGVVPLPQEVTLTNG
                     NPFVLSPSTKIFYPEGNDKMKKNAEFLASYIKEITGYELATATGQPGKGISLVIDQSI
                     QNPEGYQLTVSDNGIRIAGSTDAGVFYGIQTLRKSIPATAQGMNVELPAATINDYPRF
                     AYRGMMLDVSRHFFPVDSVKTYLDILALHNQNTFHWHLSDDQGWRIEIKKYPELTQIG
                     SKRKETVIGHNSGTYDGKEYGGFYTQDQIRDVIDYAAERHITIIPEIDMPGHQLAALA
                     TYPELGCTGGPYDVWGQWGVADDVICAGNEKSMQFLEDVLSEVIDLFPSEYIHVGGDE
                     CPKVRWEKCPKCQARIKAEGIKGDKKHSAEEYLQSYVISRMEKFVESKGRHIIGWDEI
                     LEGGLAPNATVMSWRGMDGGIEAAKQKHNVVMTPNTYVYLDYYQSADTDLEPDAIGGY
                     LPLEKVYSFEPTAGISPEDQKYVIGAQANLWTEYIPTFSQVEYMIMPRIDAVADIQWS
                     DPSKKDYQTFLPRVARMTQLYDRLGYNYGKHIFDINASLTTNTENGTLDIALTKLGEG
                     DIYYTVDGSDPTIASIKYEGPVQINQDCEFKAIVVRPNGTSRIFSEDIFFNKATMKPI
                     TLKEQPSKGYVFNGAQVLVDGLRGGSNYKTGHWLGFQGKDLDATIDLKEPTEIQKVSF
                     NTNVVKGDWIMGASAVTVKVSDDGKNFKEVASKKIPELTQNDKDGLYPQEISFAPVKA
                     RYVEIIINSSKLPKWHGGAGSPAFLFVDEIEIL"
     gene            9099..11582
                     /locus_tag="ACZPB4_07900"
     CDS             9099..11582
                     /locus_tag="ACZPB4_07900"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HIR1098179.1"
                     /translation="MINKNILILSALCSCCSLWADEVVVRHYNYAGPYEVKKPFLADS
                     LDVNSKRFSDKELLNTTVPFCNLSQSGQTLDAASSGELTLPTSASSYALHLVSFYLNS
                     NRYTKGTLRINGPEISEVYVDGQPTKLTQGEASLTLEPRRYEIVIKYLSESHKENALK
                     ASFNPEKDAVVTATVNPEKRYTLSDVFDGKRIQSASLSPNGKFIIVSYQETYPGGKQS
                     SFTQILDKATGSVLVENGQCLRWMPKSNLAYYTRKGMKGTELVTLDPTSKKENILAGQ
                     LPEGSFSFGPTEDYLLFSIREKGPQERKEIQEILVPDDRQPGWRNRMFIHKYDLRTGL
                     FQRLTYGHTSTYINDISQDGHYLLFSRREPNLTERPFSRTYIYKMDLRTMHVDTLIKG
                     EKFVSRAVFSPDATQLLIDASGEAFDGIGLKIKEGQTSNTSDGQLFLYNIADKSIKSL
                     TKDFDPSVDSYEWNALDKQVYITAKDKDRVRMYSLNPSNGKIKQLQAKEDVISDYSIA
                     NQAFEMVYFGLSASNSQRLYTYNLKNDASSCLIDLSKEILRDVTLGEVQDWNFVSAQG
                     DTIYGRFYLPPHFDATKKYPMIVNYYGGTTPTARVMESRYPSHVYAGLGYIVYIIQAS
                     GATGFGQEFSARHVNAWGKLTADEIIEGTKKFCEQHPFVNTKKIGCMGASYGGFMTQY
                     LQTKTDIFAAAMSHAGISDITSYWGEGYWGYSYSSLASANSYPWNARDMYTLQSPLFN
                     ADKINTPILFLHGTADTNVPIGESIQMFTALKLLGKPTAFVQVEGENHHILDYDKRIL
                     WNNTIYAWFAKWLKDQPEWWDALYPPKSL"
     gene            12129..15245
                     /locus_tag="ACZPB4_07905"
     CDS             12129..15245
                     /locus_tag="ACZPB4_07905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SusC/RagA family TonB-linked outer membrane
                     protein"
                     /protein_id="HIR1098180.1"
                     /translation="MKRLTYLLLCLFASIAFATAQTTKVTGTVISAEDDGPIIGASIV
                     VAGTTTGTVTDYNGAFTLDVPSNAKKLIVSYIGMKSVEVAVKPIIKVTMESDSQNLDE
                     VVVVGYGTQRKKDVTSAISKVGGEDLSNLATASFDSQLAGRAAGVQVTTPSGVLGSGP
                     QFKIRGMSTISSNSQPLFIVDGMPIATGDNADGKTGLGMAYASYNAMSDINPNDIESI
                     EILKDGAATAIYGSRAANGVVLITTKKGSKGRTQVTYDGYVSAASAAKLHDLLGAKDF
                     VTIANEKYENWGMKGQAVYDPNGPDTNWNDYIFRTGFQHNHSLSASGGTDKSQYYVSL
                     GFTEQEGIIRANDLNRLSLKADLTQQATKWLRIGLNGQMTRTRVNGVMNDENSLGGVG
                     FAGTRMLPNVSVFNPDDPTGYNIDAENRKTLGRGSNLSYIDNGIQNIVWALDNNVNRT
                     TNTRTLGGGWAEITFMDGLTLKTQAGLDISNVKDFMVWNPESGDGYGYGGLLEEINTT
                     YTNWNWQNVINFNRTFNDVHNLTATAVQEYTHQEYEYTDATVQQISDAFFTDHIISNT
                     FGERFVSGGKTFMGLASYMFRANYNYDSKYYIGASVRTDGLSSLPTDTRWGTFWGGSA
                     AWRISREKFWSESTINDWFNDLRIRASYATIGNSDLGNYFPYLGTYGAKKAGSNTAIA
                     WNRMGNSQLKWETTETFDIGLDGSFFNNRLTFELAYWQKNSKDLVLEVPTAPTAGIPY
                     NSYFDNIGKIKNSGMELTVNATIIATKDWNWQTNFNFSTAKNTVKSLYGGTDIVDNYT
                     IIREGESYRSLYGYDYYGVNAANGNPIWSKADGSLVQFDTFGSYDYAEYDPSNPSDVS
                     KASSLDASDRKVLGSSMPTWYGGWNNTVSYKNFDLNVFFRFSGGNKIMNASRQSALFN
                     MDFSNNGTEILGRWISPEQPGDGMTPKIGYGDASSLFNDGYTDSHFVESGNYLKLSTL
                     ALGYTLPKAVVFKLNMTKIRFYVQGQNLLTITGYSGLDPETNSRLGVDWNGMPQQRSF
                     TFGANITF"
     gene            15273..16868
                     /locus_tag="ACZPB4_07910"
     CDS             15273..16868
                     /locus_tag="ACZPB4_07910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RagB/SusD family nutrient uptake outer membrane
                     protein"
                     /protein_id="HIR1098181.1"
                     /translation="MLYKKLYKNISVVALGTALFSLPVFTACESDVVDLEPVDKFSEL
                     TAYGTEERCELAVVGAYDAAQCGMYVDPNDFGWARGYPFGAASILQGEMRGEDMNLTA
                     QFYDYTYSATYNLTTANNVAMWETSFEAINRYNTVYAGIEGAVAAGVITEEKGNQYKG
                     ECLFLRALTYHNLMIHYALPYNVEGNNNYGMPIYTKAVNDPSQLAEQQSIGRSTVKET
                     YDQILSDLNNAESMLPDIIDADKIGRASKGAAIALKTRVYLHMRDWNNVVTEAKKLEG
                     GRFILETNPATPFVSYKDNQESIFSIPNDSQDNASVNGAMSAMMSAREGGRAMCPTSP
                     TLYNSKFWKGDDKRRNLVLYRASDDYYFCDKYQNPQTREEYAPILRYAEVLLNEAEAA
                     ARAGDKTLALEKLNQVRDRSLADPATQTYKAGDFANTKALVEAILWERRIEFQGEGRR
                     WEDIHRLAADDLLPSGGIPAKIEYNNAKGQGAFVVGGEVKAEWFGNSKQFIPYTDKRF
                     IWPIPLNDILRNPTLAAQQNAGW"
     gene            17048..20737
                     /gene="purL"
                     /locus_tag="ACZPB4_07915"
                     /gene_synonym="purI"
     CDS             17048..20737
                     /gene="purL"
                     /locus_tag="ACZPB4_07915"
                     /gene_synonym="purI"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HIR1098182.1"
                     /translation="MILFFQSSTKTVLAVEAAHAFSPEDTQKLVWLFSEATPVQSETL
                     EGWYVGPRREMITPWSTNAVEITQNMGLTGISRIEEYFPVSSGDADHDPMLQRIYNGL
                     NQEIFTISKKPDPIVYIEDLEVYNQQEGLALSQEEIAYLNEVSQKLGRKLTDSEVFGF
                     SQVNSEHCRHKIFGGVFIIDGEEKESSLFNLIKKTSAENPNKLVSAYKDNVAFNEGPT
                     VEQFAPLSGDKPDFFAVKDIKTVISLKAETHNFPTTVEPFNGAATGTGGEIRDRLGGG
                     KASLPIAGTAVYMTSYPRTEGAREWEKVLDPRPWLYQTPEQILIKASNGASDFGNKFG
                     QPLICGSLLTFEHTENDKKYAYDKVIMLAGGVGFANMRDALKGDPEPGEKVVVIGGDN
                     YRIGMGGGAVSSVNTGQYTSGIELNAVQRANPEMQKRAANVIRAIAESDENPIVSIHD
                     HGAGGHLNCLSELVEATGGHIDMSKLPIGDPTLSAKEIVGNESQERMGLLMKEEDVAR
                     VKRIADRERAPMYVVGETTNDMKFVFEQADGVKPIDIKLEYMFGKPPRTVMTDHTVTE
                     SYQPVVYKESELHHYLENVLQLEAVACKDWLTNKVDRSVTGKIARQQCQGELQLPLSD
                     LGAVALDYRGKAGIATSIGHAPQVAMVDPAAGSVMAIAESLTNIVFAPLTDKLESVSL
                     SANWMWPCRNEGEDARLYTAVQAASDFACSLGINIPTGKDSLSMTQKYGDDKVIAPGT
                     VIISAGAEVSDIKKIVSPVLAQDKNTYIYYIDFSFDTLKLGGSAFAQALNKLGNEVPT
                     VKDPEYFRDAFNAVQDAIEKRLILAGHDISAGGMIIALLEMCFANVEGGLDVNLDKIS
                     ESDIVKILFAENPGILVQVKDKKAFEKLMEEAGVGFAIIAKPTDERHVLVSKDGIQYH
                     FGIDYMRDVWYESSYKLDVKQSGSVCAGNRFENYKMQPVQYKFHKDFTGKLSSYGLSA
                     ERRAPNGIKAAVIREKGTQCERETAYALYLAGFDVKDVHMTDLASGRETLEDVNFIVF
                     CGGFSNSDVLGSAKGWAGGFLYNEKAKKAIDNYYARKDTLSMGICNGCQLMAELGLVY
                     PEHEKKHKMVHNDSHKFESNFVSLEIPKNNSVMFGSLSGTKLGVWVAHGEGKFEFPYE
                     EKEYNIIAKYNYDGYPANPNGSPWSVAGVCSKDGRHLAMMPHPERAIFPWQCGYYPAD
                     RKENDEVTPWIEAFVNARKWIENNK"
     gene            21006..21656
                     /locus_tag="ACZPB4_07920"
     CDS             21006..21656
                     /locus_tag="ACZPB4_07920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098183.1"
                     /translation="MERLFKIRIFTVMFFLAVASIAANAKESKKEGDNYHAKQILIVG
                     LHDNVKSNYFYNGMIAEETGMKADSIDQTYNTIIAENIAASVKNGDCKFIPANATQVT
                     GQVLNEIKVNGESEDCYSDLSAVPTEELQKVLDNADADYLLVLNQHYLKWQDQPLRTL
                     FHIVSYTLFDKDKNEVYRGNNFFTCMNLENPDKLRKSSRKSSSKIASTIIKTLDED"
     gene            21826..24993
                     /locus_tag="ACZPB4_07925"
     CDS             21826..24993
                     /locus_tag="ACZPB4_07925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA];
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HIR1098184.1"
                     /translation="MRMFNKLTCRLLACLLFFNCLPALLSAQGTQAIITGTVMDNKGE
                     SVIGATIQVKNESTGFFTGSITNDKGEYTIKQLPLGSPYTVTASYIGYGEQKKTGYAL
                     NQGDMLRVDFKLAEESVEIQAVEVVANSLKNMVPKIGAATSISAQNITKLPVNGRNFT
                     SLMDLSPLSSGGNIAGQLSSSTNYTIDGMTAKGTVASGTTSGAYTISMEAVREFEVVT
                     NQYDVTNGRSGGGTVSAVTKSGTNTFTGSVFGFGRADWLSSSYDIRGNKSTSDFSTYQ
                     YGFSLGGPIVKDRAHFYVVWDHQQDSRPIYIADIKTAADESRYNVTQSTLDRYLDIAR
                     TKYGVSNDPQFGEFGKKKQTNAVFARIDWQLNATNLLTIRNNFINEDNKQSESDNSSI
                     NLYEVWIDRKSHNNSLLATLRSVLSPKLTNELKLQHFLVYEATTPNKQLPSSNIPRAI
                     VENVESISGDKSMYTSIQLGGQRYAPEHFKDNVLQLVDNMYYNTDRINYTFGADFMYT
                     NMKSLYGSEMNGRFYFTGLDNFEHMTPYRYAREIALVDDPTVKMNTLNSAIYGQLQTK
                     LFTGFEVMAGIRADYTRYFNHANFNQTVYDELGLRTDNVISTFQLQPRVQFTWDVNDK
                     HQDIIRLGAGIFGSDLNNYSMINNMLFDGTKVASVDIQGNLVPTPNFPAYRKDPSTAP
                     GVDLFNNPNIQKISTINMNSKDARVPVVYKLNASYTHFFSDRLRVGISAYANWARHNY
                     MYVDRNMVDEPYFRIAAEGNRGVFVPAESINTKNGATDWMQGRKSDKVGRVLELISDG
                     KINQYAFVVDGTWRYFKDGELSFSYTWNDSKDNTSYNGNVANTATLALMVKDDPRDLS
                     TMTYSDNQFRHKVVFYGTAPSFWGISVGLRFSGIGGTRYSLAVSGNMNGDFVSSNDLA
                     YIYDPNDSNTPQYLREGIQAILDNPEAEKSVKDYIRKNYGKVAERNGGVNGFYGTFDL
                     RLNKNFKIYKTHSIEASIDFFNFLNMLNKDWGAGHNLGKQNIYSIKSFDAEKKQYVYN
                     VNKNTGVSNMNGNPWQIQIGVRYKF"
     gene            25032..26450
                     /locus_tag="ACZPB4_07930"
     CDS             25032..26450
                     /locus_tag="ACZPB4_07930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcineurin-like phosphoesterase C-terminal
                     domain-containing protein"
                     /protein_id="HIR1098185.1"
                     /translation="MKKQFLSFTLLLALSTWIAQAATVRGTVSDTAGKPLQGVVVTDG
                     YNFTQTNERGEYSLDSNLDKSRFVYLSVPGNYEIEQTKGIPDLFYQQLDKSKEINEHD
                     FTLTPRKQPIDGFVYLAISDPQTIDERQMKRFREETIPDLKQTIERYQGKEVYGMALG
                     DITWDRMDLFTPYKEAVSVLGIPMFSVIGNHDHDLRYPALSNQKVTEESYAERIYEDH
                     FGPYNYSFNVGDAHIITLKDIDYYKDKKYDERFGKEQLEWLKNDLSYVKPGTLVFINV
                     HAPVFNQTDKGGGNAEDAESLKEIVSPYNVHIFAGHTHFFENNQVTPNLYEHNIGAAC
                     GAWWAGHVNRCGTPNGYLVVEVKGNAATWYYKATGHDSNYQFRVYKPNEFKSQADYLV
                     VNVWDWDPTYQVTWSENGIEKGRMEQFDDEDQDYIDMHGKPSGYHTSHLFRCHPSAGV
                     KDVQIKVINRFGETFTKNVTLP"
     gene            26690..27961
                     /locus_tag="ACZPB4_07935"
     CDS             26690..27961
                     /locus_tag="ACZPB4_07935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HIR1098186.1"
                     /translation="MDDRFKTLEKYNLWGGNDFPTGYKRQDYLDRILSYTGNRLIKVL
                     VGQRRVGKSYLLRQLASHLANSGVNPRNIFFINCELSAFYFLKTNEDLDSLFNLYLKQ
                     INPQGRIYLFIDEIQNVEGWERFANSYSQDYTAEYELFISGSNSKMLSGELATLLAGR
                     YVEFAIYPFSYTEFLGITQKENNKVHYLEYMQSSGMPELYHLSQPEVQRNYISALKDT
                     VLLRDIIQRQNIKDAKLLEDIFVYLVNNASNLISIRNITNYFKSSGRKTSYDTIASYI
                     SYIEDTFLVHKVEKYQIKGKETIAGNCKYYINDLGFNNYLYQGFGYGIGYKLENLIYL
                     DLLRAGYQIYVGSIKNKEVDFVAIKGERVIYLQSTYLLIDKETIEREYASLEAIEDNY
                     EKIVVSLDDLPLPSKEGIKHVQAWNLSHAIL"
     gene            complement(28721..31630)
                     /locus_tag="ACZPB4_07940"
     CDS             complement(28721..31630)
                     /locus_tag="ACZPB4_07940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6383 domain-containing protein"
                     /protein_id="HIR1098187.1"
                     /translation="MNKRISTMFASFLLMAGVAFAADGTTYSQKEAKPTEGLKVYLGN
                     EEGTSFLKSAKVTDAAYKFANTVTESEAGVFTVTGVKTENGKLMFKLVDAAGKVVYGK
                     EGTTFVEAASEDDVKKGYCWFTYDDNNTDDNYNDDKITLGGKPLAYDMATAANVAKML
                     IAKKGTTSSDLNSNLSGKGFSFKFPNAASEADVNPFGEQMFAIDASTVNSTLELGETE
                     VSGECFVVANAAGLKLAKEGGVTADNLKAATFIVLNPNATFGITSLDAAKGEGFGFTT
                     VKGEKLNATNVKKDGKIAFMNAIYGVSEDDLANKAGQYTIKMTGVKVTKGTDENFGSE
                     LTVYVGAYSLTTGGLKTYITTKGSTDKLSLAQTTGNTWAKASDLLKTDGAAIYNIYFT
                     GTKPADGEEGESLYGKYLVSTYAKTEEARATASFSNEALAPAKVDLKAPVAQWVIVSM
                     QGSGAVTFKNLETNETFNANLYKTDKAGIYQAVKTSVGDIPAENIKLVAVSANDGFLA
                     LSDAQLKQKAQLVFNGESSVAVEKVYMNYNTDGSKFEPVSDAAKSLEKAEAVKNNVEY
                     IYLKDDEVAKKKADMLTIQAYYLVDDKKGLKHESSDYKLVDYNDKKADYLSRLVFKKN
                     VDGTYSVICLDEALDADEAVDNYNKVVKPDAKMLKVDVNAPSFDEVLVGAEKADYAKV
                     VVDFFQMGASLDAVPRHATLDSEEGSISLKENKNGILEGIIGAEGLTFWLDTADSKAE
                     LPSFYISKGIAEGDSVAPVRNFLYFAQDSLRYWNEAQAKFTYDENYGLEGTYGAEADQ
                     NTDVKAIFRPATLAGVDTINTTVNGKNVVVAAEAKEDVCLGGINNFKFYITKLDAGYS
                     VRPVDQPTKYLYALNGKLGFTSDTSKALPVTVGEGNPTSNESIDNSASSSVVVIGNAG
                     SVTIQGAQGEMAYVRNLLGMPLAETVVISDNATIAVPAGIVLVTVGDETVKVVVK"
BASE COUNT         9269 a         7539 c         6774 g         8194 t
ORIGIN      
        1 cttctcgaag ttctgtatgc cgataggata aattgtctgg ttcatagcga tgatcgttta
       61 gatatactta ccatgaacaa agatagacat tcctttttat cagaacaaga taagaacata
      121 tgatctcaaa aactttcctt gacaatacgc ttgactggca ggaaaaaacg ctcgatcaaa
      181 cgcaattcct cccattttga ataagaacta atagcagatc aaaattatat gccagaaaac
      241 gcagtagtac ttacttcgtc tacaaatata tacttacttg cccgatgaag tatatattct
      301 ccggttaagt aagtactact gcgttttcca caccatatca aaaaaaggag gtatgcccaa
      361 ctgacatacc tcctttttta tattaagttt aacttattaa tatcccgggt tctgttccaa
      421 caacgggttc gcacccaatg acaattgatg caatggataa cgattgtatt tctcatcgtt
      481 cgtagcctta tgatcccacc aatcctctgt cacatatgcg tcccaacgga ttaagtccgt
      541 gcgacgacgg gcctcgcgca agaactcttg catccattcc ttcagcatac ggtatttatc
      601 caaattggca gcggtaacag gatccgggtc gtttccaccc tcgaagttac gcttacggat
      661 ggagttgatg atatcggccg caccattctt atcgcccaaa cgcatcttac attccgccaa
      721 agtataatag atctctgtca gacgaattac aggacaatct gggttgaaac gttccttgaa
      781 ctcatcttga ttaggcagag gactaaattt aagaacacgc acgcctgagt tctcctctgc
      841 atcggcaatc gtagaagtca gatccttaag actggctacc gtattgccca cctggctgat
      901 atgagcgatc tggtctacga cattcaagac cttgccggca tactcgcggg cacccaagca
      961 tttgtactcg gggaaatccg ggttttgcaa ctcaccaacg ataaacatac cacggtattt
     1021 gcgaccaccc tcatatacat actgctgctt acggatatcc ttgtcgttga atgtctcgta
     1081 tggattacct acgttaaact tatacaagtt accctccgga tcgcgactag ggcataggca
     1141 aagcccatta ttaccactag catcctgcaa gccccctaag aaatccttga aattataggg
     1201 aagagtgaag gcagtcaaac caccatccgt ctcacctttg gcattctcgg aaggtactgt
     1261 ccagataatc tccgggcaag tctcattacc ccaaccaaag atctcggtga aatggttggc
     1321 caatttatac tgaccatact ttccatcgat aatatcctga caaatcttag cggcctcctc
     1381 atacatcggt ttattgatat acgattcagc gttgaaatac aaacgaacct tcaaagccgc
     1441 agccacagca cgatggataa cgttcgtctc gggtgctccc aaggtctcct tcaacggaag
     1501 attcggcata gatacatcca acaaggagtc gataaaatgg aaagtctcca catctgtagc
     1561 acgagccttc acatcctcct tcgtagatgt gtaaagaggc ataccaccaa acatgtccaa
     1621 accatccaaa taaaaagagg cagccaatac gttcaactga ttaatcattg atacacgatc
     1681 ctcctcagtc aagcccaccg atacgaaatc gatattctcc aaatcctcca aggcactcca
     1741 cgactgagcc acacccatcg tcgtcaagtc ccatccatcc ttcatcgggc tcatatcatc
     1801 cataaaatga tgatgatgca tgttctgata aacggcgcca tcaaaccagt cattaccacg
     1861 agtaggcaca cacatagcat cagttcccac ttccatcaag cgcacacgag cgtcgttatg
     1921 agctacccac caacgccaat gcgtaaaagg acgattaaaa cgcgaccaaa tcgcgtctgc
     1981 attcgtataa tacgtgtcgg gaacaacctg cgaatagaag gtaggatcca catcacatga
     2041 ggtacccagc agcaagcaag cagccccggc taccatccaa tttgttatct tgctaatttt
     2101 cattttcttc ttaccttttt tagaatgtta cttgaatacc taaagtgtat gtgcggacaa
     2161 tcgggtcaca gttccaaacc ttatcggtac cacctgtcca gcctgtgata tctacctctg
     2221 gattatgtcc gctatatcct gtaatagtcg ctacattgcc gacagttcca tatacgcgca
     2281 gacgctctgc ccattttgta tacttattca acgccaatgt ataacctaac gtaatcgcat
     2341 ctatcttcaa gaacgagcca tcctccaaga agtaatcgca aagctgcttc acgccgcgaa
     2401 tgtccttaaa cttcggatcg tcaagcgccg gtttccaaag attccactgg ccggcaccac
     2461 tctgtccctg gatacccaag tacatcggat aagtattcaa gacatcgaaa cctatccaac
     2521 tacgcatatt aatacccaag tcaaaattct tataagtaaa ggtattgttc catcccatca
     2581 tcaccttggg cagataatta ccgatatatt gtttgtcgtc tacactcttc tgggaagcag
     2641 gtataacctc accatcctta ttgtacaaaa ggaagtctcc tttatcgtcg aatccagcga
     2701 atttccacat atggaacgca ccgatctctg ccccctcttc aatacgagcg gcatcgcccg
     2761 gccatcccgg ttcatccata gcgttaccat ccatacgtga attgttgcca tacatcgtaa
     2821 ggatcttacc cgagttatgg ctcatattca agctggaagt ccaagtgaag tccttattct
     2881 ggatgatgtc accaccaacc tcgaactccc atcctttact ctccatctcg ccaatattct
     2941 gccattgctt gccatttgga tacggtggct gtggaacatt cacctcgtag atcataccat
     3001 cgatcttacg acgatagtaa tcgaacttac catacatacg gttgccaaag aatgagtagt
     3061 ccacaccgat attccactcc ttcttctcct cccatcccaa ataaggattc acgttagagc
     3121 tcggaccata gacataagcc cagcttccgc taggaagcat ccagtattgg tcgcggctca
     3181 acgtattagc catataggaa gcatcgaagt cgttattacc tgtaacacca taaccaaaac
     3241 gaaccttcaa gtcgctcacc cagtcaaact ccttcatgaa ctcctcggca gatacacgcc
     3301 aacctccgga caacgcccag aagttacccc aacggttctc ggcggcaaac tttgatgatc
     3361 cctcatgacg gattgtggca gaaaccatat atttgtcatt gtaagagtag ttggcacgag
     3421 catacaatgc aaacaggcgc tctgtgatat tcttacctga tcccatggca gccttaccat
     3481 ctgtcagata tgaacccgca cctaagtccc aatatttcag tccctcaaca ccgaagtcat
     3541 agttctcagc attgaaattc tctccattct tctcgaaata agagtaacca gcaacggcat
     3601 tcaagctatg gccacccttg aactccttca gatatgtgaa gtaaccctca gatgtaaggt
     3661 gctcagtctt tgagaactca agtttagccc aaccgccacg gttgtttgtc acctcatcgc
     3721 ggtggtaacg agagcggaac tggtggagct cccactgacg gttctcgtaa cccaatgtct
     3781 gagaatagct caatccctca atgggcttga tgttcaactt cattgtaacc tcaggcttga
     3841 accacttgtc caatccctca tagtcggtca acatacggtc ggctacgata ttatagtcca
     3901 atgtctcgcc agtccacaca ttatagcctg tcgggctttc cgggtcaaat ggcgaacgag
     3961 tcgggttatt atacaacgcc tgcttgaagt ttgccttctt atcctcatcc gatccatcgg
     4021 aagtacgagc agtctgacga taatccacga tcggacggat ctctaaccaa ccatcgaaca
     4081 gcttaaagtt tgcattcaag cgtccaccat agtccttacg gttatcctta atcgtgatgc
     4141 cttcgttggt ctcatagaag aaagaggtgt acacttgtgc gttctcggta cctagctcca
     4201 aagagaggtg atgtttttgc gagaagttat ccttctgcaa aagagcgtcc caccaatcag
     4261 cgttctgccc gtaatcagtg atattcacgt ccgtacgatt gcgatattca tcggcggtca
     4321 tcatatccgg acggccatag ttttgtttct tcgaaagctc agtactataa ttcaatttta
     4381 ctttaccatt cgtgttagaa ccactcttcg ttgtgatcaa gatcacaccc gaagcagcac
     4441 gtgtaccata gatcgcacca gcggaagcat ctttcagcac atcgatagat ttgatatcgt
     4501 cttggttcaa ggcacgaata tcacctcccg ggaaaccatc gacaacgatc aatggagcct
     4561 taccagagtt gatagaggtc aaaccacgca actggatcgt ggtcgtacca ttggcactac
     4621 cattattttg caagatcaaa ccgctgatct taccttgcaa agagctggtg atatcggcac
     4681 cacccacacc cttcatcata tcgccggcag acaatgaggt aacggagctg gtcacttgct
     4741 tcttctccat cgtaccgtaa cctacgacca cgacctcttc aagagcctgg gaatcttccg
     4801 acaacgtaac atttataaca ctttgactgc caaccgggac ttccttggtc gtgtaaccga
     4861 tataagagat ttccaaaaca gcgtttgcgg gcacatcttg caacgtaacc gagccgttca
     4921 tgtcggttac gttaccgata gtagttccct tgaccaacac gttcgcgccg atcaactcac
     4981 ccattgaatc tgaaacctta accgtaatag tcttaccatt ttgcatgacc gattcaacat
     5041 tcggtccgta gttgtgcgag ggttccacag ccgccaatcc ttgaaaggag gccatacata
     5101 ggaatcccgt ggtaagcatc ataacacttg gtttgaacaa gcttaaacac aattgcttgc
     5161 tcttcttact acatttttcc atctttatta ttaaatggtt ataattaatt gagattaaca
     5221 atattcaaac accaaaaacc tactttctgc tatctctgag cgcagtccct aataaaaatg
     5281 actagctaaa acgttcgttt agactagtcg tccgcgaagt taaccattaa tttaaattaa
     5341 gcaacattca tttaaatcat ttttcgattc tattagtaat aagacttata atcaacacat
     5401 tacatccaat attaaaattg tgtcaaatgc actatcccat ccatcaaaat gactagtcta
     5461 aaccaacgtt taaaccagtc attttcacat ttattatact attgagtatg ataaaaacca
     5521 tacctttact cccccaaaga aagaatgcag aaaccatgaa actacaaatc atcgataccg
     5581 gctacttcta cgccgacgga ggcgccatgt tcggggccat tcctaaaagt gcttggagcc
     5641 gtcgctatcc gagcgacgag acaaatggtt gcgtgctcgc catgcgtagc cttgtcataa
     5701 aaacagatga cggacgcatc gtcctagtag ataacggagc gggaaataaa cacttaaaac
     5761 aactaagtta ttaccgcttc ttcaacttgg tagacctcgg cacggaatta cgaaaccgag
     5821 gaattcaacc ggaggaaatc acggatgttg tcctcaccca tctccatttc gatcattgcg
     5881 gttataccac gcaaaaggat gaatctaccg gacatttatt tctctcattc ccaaatgcga
     5941 accactgggt tagccgcaag caatgggaga atttccttca tccgaacgcc ttggagagag
     6001 attcctattt catcgagaat atgcaagccg tcgcagacgc taattcctta cggctgctag
     6061 atgccgacac atcgatttgc cccactatag agctacgcct gtacgatggg cacactccgg
     6121 gacaaattgt tccctatatc catacggagg accggacctt tgtctttgcc ggggatgtta
     6181 tcccccttgt agccagcgta tctccggaat ggatctcggc ttacgatacg tatccgatca
     6241 cgtcatacaa cgagaaactg cgcatgcttg ccgaagccgc cgaaaaaagg caagcgctca
     6301 tctactgcca tgacgcttac atccgctgca caaccgtaaa acgtgtgaat tcttattata
     6361 agaaagacaa ggaaatacct ctcaagaaga cgtttctttt cccttagtcc ctagcccttt
     6421 tccctttaga ccttaggtgt ttcttccata ttccttagac atttcttata gaagtattca
     6481 tcatccacca gccgttgcat gatcgtctac caactgttgg atgatcatgc aacagctggt
     6541 ggacgatcat gcaccagttg ataaatagtc tatatatata gacaaaatcc ctaaggttat
     6601 cgcatcaaaa gtgtaaaagc attagataaa acggctaatt ctatttatct ttgggcggtg
     6661 atactgaatc aattattgtt ttacattcta aactctaaac acatgaacag cctaagcaaa
     6721 ctagcgctcg tcctgacatt ttgcacggga atgatcgctt gctccggtgg taaggccgta
     6781 aaaggagatt acggagtagt gcctttgcca caagaagtaa cattgacgaa cggaaatcct
     6841 ttcgtcctaa gtccatccac gaagatattt tatccggagg gcaatgataa gatgaagaag
     6901 aacgccgagt tcctcgcttc ttatatcaag gaaatcacgg gctatgaatt agcaaccgct
     6961 accggccagc ccggtaaggg gatcagcctc gttatcgacc aaagcatcca gaatccggaa
     7021 ggatatcaac tgaccgttag cgataacggg atacggatcg ccggaagtac ggatgccggc
     7081 gtattttatg gtatccagac attacgtaaa tcgatcccgg ccacggccca agggatgaac
     7141 gtagaattac cggcagctac catcaacgac tatccccgtt ttgcctatag aggcatgatg
     7201 ctggatgtca gccgccattt cttccccgtg gattcggtaa agacgtatct cgatatcctt
     7261 gccttgcaca accaaaatac gttccactgg catctgtccg atgaccaagg ttggcgtatc
     7321 gagatcaaga aatatccaga attgacacag atcggatcta aacgcaagga aaccgtgatc
     7381 ggccataact ccggaacata tgacggaaaa gaatacgggg gcttctatac acaagaccag
     7441 attcgcgatg tcatcgacta tgccgccgaa cgccatatca cgatcatccc ggaaatcgat
     7501 atgccgggac atcaattggc agccttggct acttacccgg aactgggatg caccgggggc
     7561 ccttatgacg tatggggcca atggggagta gccgacgacg tgatctgcgc cggaaacgag
     7621 aaatccatgc aattcctaga agacgtattg agcgaggtca tcgatctttt cccgtccgaa
     7681 tatatccatg taggtggtga tgagtgcccg aaggtacgtt gggagaaatg cccgaaatgc
     7741 caagctcgca tcaaggcgga aggtatcaag ggagataaga agcattccgc cgaggaatat
     7801 ttgcaaagct acgtgatctc ccgcatggag aaattcgtgg agagcaaagg acgccatatc
     7861 atcggctggg acgagatcct agaaggaggc ttggccccga atgccacggt aatgagctgg
     7921 agaggcatgg atggaggtat cgaggccgcc aagcaaaagc ataacgtagt catgacaccg
     7981 aatacatatg tatatctgga ttactatcaa tcagcggata cggatcttga gcccgatgct
     8041 atcggtggtt acttgccgtt agagaaagta tattcttttg agccgacagc cggtatctct
     8101 cctgaagacc agaagtacgt gatcggggcg caagccaacc tctggacgga atatatcccg
     8161 accttctcac aggtagaata catgatcatg ccccgtatcg acgccgtagc cgatatccag
     8221 tggagcgatc cgtccaagaa agattatcag acgttcctgc cccgtgtggc ccgcatgaca
     8281 caactttacg atcgcttggg atataattac ggaaagcata tcttcgatat taacgcctcc
     8341 ctgaccacca atacggagaa cggaacactc gacatagcct tgacgaagtt gggtgaagga
     8401 gatatctatt atacggtaga cggtagcgat cctacgatcg ccagcatcaa gtatgaaggc
     8461 ccggtacaga tcaaccaaga ttgcgaattc aaggcgatcg ttgtccgtcc gaacggtacg
     8521 agccgcatct tctcagaaga tatcttcttc aataaagcga cgatgaagcc catcaccttg
     8581 aaagagcaac ccagcaaagg atacgttttc aacggggcac aggtattggt agacggctta
     8641 cgtggaggaa gcaattacaa gaccggccat tggctgggtt tccaaggaaa agaccttgac
     8701 gccacgatcg atctaaagga accaaccgaa atccaaaagg tatctttcaa tacgaatgtg
     8761 gtaaaaggcg attggatcat gggagcctcc gccgtaaccg taaaggtatc cgacgatggc
     8821 aagaatttca aggaagtagc ttccaagaaa atcccggagc taacccaaaa cgacaaggac
     8881 ggtttatatc cccaagagat atccttcgcc ccggtaaagg cccgctatgt cgagattatc
     8941 atcaacagca gcaaactacc aaaatggcac ggtggcgccg gaagtcccgc attcttgttc
     9001 gtagatgaga tagaaatctt ataagataat gatacagcga gatggctgag agatacccgc
     9061 catctcgctt tcttatctta tactaaataa caaatatcat gataaacaaa aacatcttaa
     9121 ttctttcagc cctatgctcc tgttgctcac tatgggcgga tgaggttgtc gtgcgacatt
     9181 acaattacgc cggcccttac gaggtgaaaa agcctttcct agcagatagc ttggatgtaa
     9241 acagtaagag attctctgac aaggaactat tgaacacgac cgttcctttc tgcaaccttt
     9301 cccaaagcgg acaaaccctt gatgcggcgt cttccggaga gctgaccttg ccaacctcgg
     9361 cctcttccta cgcgctacat ttggtttcct tctacctgaa tagtaaccgt tatacaaaag
     9421 gcaccttaag gatcaatggc cctgagattt cagaagtcta cgtggatgga caacccacaa
     9481 aactaaccca aggagaagcc tcgttgacct tggagccgcg acgctatgaa atcgtaatta
     9541 aatatttatc cgagagccac aaagagaatg ccttaaaagc ctcattcaac ccggaaaaag
     9601 acgcggtggt aaccgcgacc gtcaatccgg agaaacgtta tacattaagt gatgtatttg
     9661 atggtaaacg catccaatcc gccagcctgt ccccgaatgg aaaattcatt atcgtctcct
     9721 atcaagaaac ctatcccggt ggaaagcagt cctcatttac ccaaatacta gacaaggcta
     9781 ccggttccgt attggttgag aacggacagt gcttacgctg gatgcctaaa agcaatctgg
     9841 cctattacac ccggaaaggg atgaaaggca cggaattggt gaccttagac cctaccagta
     9901 aaaaggagaa catccttgcc ggccaattgc ccgagggttc tttcagtttc ggacctaccg
     9961 aggactatct attattctcc atacgagaga aaggaccgca agaacgaaaa gagatccaag
    10021 agatactggt gccggatgat cgccaaccgg gatggagaaa ccgtatgttt attcataaat
    10081 atgacctgcg aaccggattg ttccaacggc tcacctatgg acatacttct acttacatca
    10141 acgatatatc tcaagacggc cactatctgc tattcagtcg cagggaaccg aatttaacgg
    10201 agcgtccttt ctcacgtaca tatatatata agatggatct acgaaccatg catgtggata
    10261 cccttataaa aggtgagaaa ttcgtaagcc gtgccgtttt ctccccggat gccacccaat
    10321 tactcattga cgcgtctgga gaggctttcg atggtatcgg attaaagatc aaagaaggac
    10381 agacatcgaa tacgagcgac gggcaattat tcctatacaa tatagcagat aaaagtataa
    10441 agtcgcttac gaaagatttt gacccctctg tcgattccta cgagtggaac gccctcgata
    10501 aacaagtcta tatcacggcg aaagataagg accgtgttcg catgtatagt ctaaacccgt
    10561 ccaacggaaa gattaagcaa cttcaagcca aggaagatgt catctccgat tactccatcg
    10621 ccaatcaagc tttcgaaatg gtttatttcg gattaagcgc ttccaattcc caaaggcttt
    10681 atacctataa cttgaaaaac gacgcctctt cctgcttgat cgatctctcc aaagagatct
    10741 tgagagacgt cactttagga gaagtacaag attggaattt cgtttccgcc caaggggata
    10801 cgatttacgg ccgcttctat ctccctcctc attttgacgc gaccaagaaa tatccgatga
    10861 tcgtgaatta ttacggagga acaactccta cggcccgggt gatggaaagc cgttatcctt
    10921 cgcatgtata cgccggctta gggtacatcg tctacatcat acaggccagt ggagcgactg
    10981 ggttcggcca agagttctcc gcacgccatg tcaacgcatg gggtaaactt accgctgacg
    11041 agatcatcga aggcacgaaa aagttctgtg agcagcatcc ttttgtcaac acgaagaaaa
    11101 tcggttgcat gggggcttca tacggaggtt tcatgactca atacctacaa acaaaaacag
    11161 atatattcgc ggcggccatg tctcatgcgg gaatcagcga catcaccagc tattggggag
    11221 aaggttactg gggatattca tacagctcgt tggctagcgc taacagttat ccatggaatg
    11281 cccgggatat gtacacttta caaagtccgc tatttaacgc agacaagatc aataccccga
    11341 tcttgttctt acatggaacc gcagacacga atgttccgat tggagagagc atccagatgt
    11401 ttaccgcatt aaaattattg ggtaagccta cagcgtttgt ccaggtagaa ggagagaacc
    11461 accatatact ggattacgac aaacgtatct tgtggaataa cacaatttac gcatggttcg
    11521 ctaagtggtt gaaagatcaa ccggagtggt gggacgcatt atatcctccg aaaagtctat
    11581 aaaaatcaaa ataggtcact ctattcatat atatctaaag agtatcttta attagatact
    11641 ctttttttat ttaaatacat tagatagtat ttatgaaata ccttagtctc cgaagaacta
    11701 aatcactttt ccgttcaata tttattaatt attataaata tcttaataaa ttatagaaca
    11761 tacaacctat gtaaacatct gttatgtcta attgtactat ttacagcaag cattttattt
    11821 taatagctgt acggcaaata taaagatata tttgcaataa acaaacatat tgacaataaa
    11881 aataaactta cacgtaactt tgtcaatacg gattatttta agttatatgt taatttaata
    11941 cattctagta ttaatatata gtattaatat gcaaattatt tttaactcaa tcccgcatca
    12001 atgctaggaa gtaacaccaa agtaccttac tctcatgaag ttcttcggaa actaagtcaa
    12061 tcgactaagt ggcaacaatt gattacaacg atctatttat taacaaatta aacaaaaagt
    12121 atgtgtctat gaaaaggttg acttatctat tactatgctt gtttgcaagt atagcgttcg
    12181 caacggctca gaccacgaag gtgaccggta cggttatctc ggcggaagac gatggaccta
    12241 tcattggagc ctctatcgta gtagctggta ctactaccgg tactgtaacg gattacaacg
    12301 gagcgttcac cttggatgtt ccttctaacg cgaaaaagct aatcgtttcc tacatcggta
    12361 tgaaatctgt ggaagtggca gtaaaaccaa tcattaaagt cacgatggag tctgactctc
    12421 agaacttgga tgaagtcgtg gttgtcggtt acggaactca aagaaaaaag gatgtgacga
    12481 gtgccatatc taaagtagga ggtgaagact taagcaactt ggcaacagcg tctttcgact
    12541 ctcaattagc tggacgtgcc gctggtgtac aggttacgac tcctagtggc gtattgggaa
    12601 gcggtcctca attcaagatc cgtggtatga gtacgatcag ttctaactct cagccgttat
    12661 tcatcgtaga tggcatgccg atcgccaccg gtgataacgc cgatggaaaa accggcttag
    12721 gaatggctta cgcttcttac aacgcgatgt ctgatattaa cccgaatgac atcgaatcca
    12781 ttgaaatatt gaaagacggt gcggctacag ctatctatgg ctcccgtgcg gcaaatggag
    12841 ttgtattgat cacaactaaa aaaggctcca agggacgtac tcaagtaact tacgatggct
    12901 atgtaagcgc agccagcgca gctaaattgc atgatcttct gggagcgaaa gatttcgtga
    12961 ctatcgctaa cgagaaatac gagaactggg gaatgaaagg acaggctgtt tacgatccga
    13021 acggaccgga cacaaactgg aatgattata ttttccgtac aggtttccag cacaatcata
    13081 gcttatccgc cagtggtggt acggataaaa gccaatatta tgtatcatta ggtttcacgg
    13141 aacaagaagg tatcattcgc gccaatgact taaaccgttt gagcttaaag gcagatttga
    13201 cacaacaagc gacaaaatgg ttacgcatcg gattaaatgg ccagatgacc cgtacccggg
    13261 ttaatggtgt catgaatgac gagaattcat tgggtggcgt aggtttcgcc ggcactcgta
    13321 tgcttccaaa cgtatctgta ttcaatccgg atgatcctac tggttacaat atcgacgctg
    13381 aaaaccgtaa gacattaggt cgcggaagca acctttccta tattgataat ggcatccaga
    13441 atatcgtttg ggcattagac aataacgtaa accgtacgac taatacccgc acattaggtg
    13501 gtggatgggc tgagatcaca ttcatggacg gattgacatt aaaaacacag gccggtctgg
    13561 atatctcgaa tgttaaagat ttcatggtat ggaatccgga atcaggagac ggatacggct
    13621 atggcggctt attggaagaa atcaatacca catacacgaa ctggaactgg caaaacgtaa
    13681 tcaactttaa ccgtacattc aatgatgtac ataatctgac ggcgacagcg gtacaagagt
    13741 atacccatca agaatatgaa tatacggacg caaccgtgca acaaatatcc gatgctttct
    13801 tcaccgacca tatcatttcc aacacatttg gtgagagatt cgtatctgga ggtaaaacgt
    13861 ttatgggatt agcctcctat atgttccgtg cgaattacaa ctatgatagt aaatattata
    13921 tcggagcctc tgtccgcacg gacggcttat ccagccttcc gacagacact cgctggggta
    13981 cattctgggg aggatcagcc gcttggcgta tctctcgcga aaaattctgg agcgaatcaa
    14041 ctattaatga ttggtttaac gacttacgta tccgtgccag ctacgctaca atcggaaact
    14101 ctgacctagg gaattatttc ccttatctgg gaacttacgg ggcgaagaaa gcaggatcga
    14161 atacagctat cgcttggaac cgtatgggta acagccagct caaatgggaa acaaccgaga
    14221 ctttcgatat cggattggat ggctctttct ttaataaccg cctgacattc gagctagctt
    14281 attggcaaaa gaactccaaa gacttggtgt tggaagttcc tacagcacct accgctggta
    14341 ttccttacaa ctcatatttt gataatatcg gtaagatcaa gaactccggt atggaattga
    14401 cagttaacgc tacaatcatc gctaccaaag attggaactg gcaaactaat ttcaacttct
    14461 ccacggctaa gaacacggtg aagagcttat atggcggaac agacatcgta gacaattaca
    14521 caatcattcg tgaaggagag tcatatagat ctttatatgg atatgattat tacggcgtaa
    14581 acgccgcaaa cggtaatccg atctggagta aggcggacgg ttcattagtg caattcgaca
    14641 cattcggctc ttacgactat gcggaatatg atccttccaa tccttcggat gtctccaagg
    14701 cttcttcctt ggacgctagc gaccgtaagg tattaggttc atctatgcct acttggtacg
    14761 gaggttggaa taatacagtt tcttacaaga atttcgattt aaatgtattc ttccgcttct
    14821 ccggaggtaa taagatcatg aacgcttctc gtcaaagcgc attgttcaat atggatttct
    14881 ccaacaatgg aacagaaatc ttaggccgct ggatttctcc agagcaaccg ggtgacggca
    14941 tgactccaaa aatcggttat ggagacgcct cttccttatt caatgatgga tatacggatt
    15001 cacacttcgt tgagagcggc aattacctaa aactatcgac gttagcttta ggctatacac
    15061 taccgaaggc ggtcgtattc aaactgaaca tgacaaagat tcgtttctat gttcaaggac
    15121 agaacttact cactatcaca ggttattccg gattggatcc tgagacaaac tctcgcttag
    15181 gtgtagattg gaacggtatg ccacagcaac gttcattcac ttttggagcg aacattacat
    15241 tctaatttca caaactaaga aaagttacaa ttatgttata caagaaatta tataaaaaca
    15301 tttcagtagt agcgctaggg acagccctgt tctcgctacc cgtgttcacc gcctgcgaaa
    15361 gcgacgtcgt agaccttgaa cctgttgaca aattctccga gcttacggca tacgggacag
    15421 aagaacgttg cgagttagcc gtagtcggag cttacgatgc cgcacaatgt ggtatgtacg
    15481 tagatccgaa tgactttggg tgggcacgcg gttatccttt tggagcggcc agtatattgc
    15541 aaggcgaaat gcgcggtgaa gatatgaacc taaccgccca attctatgat tatacctatt
    15601 ccgcaaccta taacttgact accgctaata acgtggcgat gtgggaaacc tctttcgagg
    15661 ctattaaccg ctataatacg gtatacgcag gtatagaagg cgcggtagcg gcgggtgtca
    15721 taaccgaaga gaaagggaat cagtacaaag gagaatgcct gttcttacgt gcgttaacct
    15781 atcataactt gatgatccat tatgccctgc cctacaacgt agaaggtaac aataactacg
    15841 gtatgcctat ttacacgaaa gccgtaaacg accccagcca actcgctgag caacaaagca
    15901 taggccgttc taccgttaag gagacttacg atcagatatt aagcgacctg aataatgcgg
    15961 aaagcatgct tccggacatt attgatgctg ataagatcgg acgtgcgagc aaaggtgccg
    16021 ccatcgcatt gaaaacgcgc gtatatttac atatgcgtga ttggaacaat gtagttactg
    16081 aagctaagaa actggaaggc ggacgtttca ttctggaaac caatcctgcc actcctttcg
    16141 tttcttacaa agacaatcag gaatctatat tctccattcc gaatgactct caagataacg
    16201 catctgtaaa tggagctatg tccgctatga tgtctgcccg tgaaggtggc cgtgcgatgt
    16261 gcccgacatc ccctaccctt tacaactcca aattctggaa aggggatgac aagcgtcgta
    16321 acctcgtcct ttatcgtgcg tctgacgatt attacttctg tgataaatac cagaatcccc
    16381 aaacacgtga agagtatgcc ccgatcctgc gctatgccga ggtattgcta aacgaggccg
    16441 aggctgccgc acgtgcggga gacaagactc tcgcattgga gaaattgaat caagtaagag
    16501 accgttcttt ggccgacccc gctacacaaa cgtataaggc tggcgatttc gccaacacga
    16561 aagcgctggt agaagctatc ctttgggaac gtcgcattga gttccaaggt gaaggtcgcc
    16621 gttgggaaga cattcatcgt ttagcggctg acgatttact gccgtccggt ggtattcccg
    16681 caaagatcga atacaacaat gccaaaggcc aaggtgcttt tgtcgttggt ggagaagtaa
    16741 aagcagaatg gttcggcaac agcaaacagt tcatcccgta cacagataaa cgctttattt
    16801 ggccgattcc attgaatgat atattaagaa accccacgct agccgcacaa cagaacgcag
    16861 gctggtagaa tatagacaca ctcttatttt ttactatgca ggggacatga gagggcgaga
    16921 ccgggaggtt ccgccctctt ttcttttaaa acgtattgac ataataattc acgggaaatc
    16981 attatctttg cactctctaa aagaggctta ttcgttattt cgtgataaat actaataaat
    17041 caacgatatg attctattct ttcaatcttc aacaaagacg gtgctggctg tagaggccgc
    17101 gcacgctttc tctcctgaag acactcaaaa actggtttgg ttgtttagcg aggcgactcc
    17161 tgttcaatca gaaacattgg aaggctggta cgtagggcca cgccgggaaa tgattacccc
    17221 gtggagtacg aacgccgttg aaattaccca gaacatgggc ctgaccggta tttcccgtat
    17281 tgaggaatat tttcctgttt cttctggcga tgcggatcac gatccgatgt tgcaacgtat
    17341 ctacaatggc ttgaatcagg agatcttcac gatcagtaaa aaaccggatc ctattgtcta
    17401 cattgaggat ttggaagtgt acaaccaaca agagggcttg gctctaagcc aagaggagat
    17461 cgcttacttg aacgaggtaa gccagaagtt gggacgtaag ttgaccgata gcgaggtgtt
    17521 cggtttctcc caagtaaact cggaacactg ccgacataaa atattcggag gtgtattcat
    17581 catcgacggc gaggaaaaag aaagttcctt gttcaacttg atcaagaaaa cttccgccga
    17641 gaaccctaat aaattggttt ccgcttataa agataacgta gcgttcaatg aaggaccgac
    17701 ggtagagcaa ttcgctcccc tatccggtga caaacccgat ttcttcgccg taaaagatat
    17761 caagacggtt atctccttga aagccgagac gcataacttc ccgacaaccg ttgagccgtt
    17821 caacggtgcc gctaccggaa caggtggtga gattcgtgac cgtctgggcg gtggtaaggc
    17881 atccttgccg atagcgggaa cagcggtcta tatgacctct taccctcgta cggaaggcgc
    17941 tcgcgaatgg gagaaagtcc tagaccctcg tccttggtta taccagactc cggagcagat
    18001 cttgatcaag gcttccaatg gcgcttccga tttcggtaat aaatttggcc agccgcttat
    18061 ctgtggttct ttattgactt tcgagcacac ggagaacgat aagaaatacg cttacgacaa
    18121 agtaatcatg cttgccggcg gtgtaggttt cgcaaatatg cgcgatgcct tgaagggcga
    18181 tccggaaccg ggcgagaaag tggtcgtgat cggtggcgat aactaccgta tcggtatggg
    18241 tggtggagcc gtctcttccg taaacacggg gcaatataca agcggtatcg agttgaacgc
    18301 cgtacagcgt gccaacccgg aaatgcagaa acgtgcggct aacgtgatcc gtgcgatcgc
    18361 cgagtctgac gagaacccga tcgtctctat ccatgaccat ggtgcgggtg gacacctcaa
    18421 ctgcttgtct gagttggtgg aggctaccgg cggacacatc gatatgagca aattgccgat
    18481 tggtgacccg actctctcag cgaaggagat cgtaggaaac gagagccaag agcgcatggg
    18541 cttattgatg aaagaagaag atgtagcccg tgtaaaacgt atcgcggatc gtgaacgtgc
    18601 cccgatgtat gtggtaggcg agactactaa cgacatgaag tttgtcttcg aacaagcgga
    18661 cggcgtaaaa cctatcgata tcaagctgga atatatgttc ggtaaaccgc ctagaacggt
    18721 tatgacagac catacggtca ctgaatctta tcaaccagtt gtttacaaag aatccgaact
    18781 tcaccattat ttggagaacg tacttcaatt ggaggccgta gcctgcaagg attggttaac
    18841 aaacaaagta gaccgttccg taaccggtaa gatcgcccgc cagcaatgtc aaggtgaatt
    18901 acaattgccg ttgagcgact taggtgccgt agcgttggat taccgcggga aagctggtat
    18961 cgctacttct atcggtcacg ctccccaggt agccatggtt gatccggccg ccggttccgt
    19021 tatggcaatc gccgagtcat tgaccaatat cgtattcgct ccgctgacag ataagttgga
    19081 gagcgtatcc ttaagtgcca actggatgtg gccatgccgt aacgaaggtg aggacgcccg
    19141 tctgtacaca gccgtacaag ccgcttccga cttcgcttgc agcttaggta ttaatatccc
    19201 gactggtaag gactccctat ccatgacgca gaagtacggt gacgataagg tgatcgcccc
    19261 gggtacggtg attatctccg ccggtgccga ggttagcgat atcaaaaaga tcgtctctcc
    19321 cgtattggca caagacaaga atacatacat ttattatata gacttctcct tcgatacctt
    19381 gaagttgggt ggttccgctt tcgctcaagc tttgaacaag ctgggtaatg aggttccgac
    19441 cgtgaaagat ccggaatact tccgtgacgc tttcaacgcc gtacaagatg cgatcgagaa
    19501 gagactcatc cttgccggac acgatatctc agcgggaggt atgatcatcg ccctgttaga
    19561 gatgtgcttc gccaacgtag agggtggttt ggatgtcaac ttggataaga tctccgagag
    19621 cgatatcgtg aagatcctgt ttgccgagaa tccgggtatc ttggttcagg taaaggacaa
    19681 gaaggcattc gaaaagttga tggaagaagc tggcgtaggt ttcgccatca tcgccaaacc
    19741 gaccgacgag cgccatgtat tggtatcgaa agacggcatc caatatcact tcggcatcga
    19801 ctatatgcgt gacgtatggt acgaatcttc ttataaactg gatgtaaagc agagcggaag
    19861 cgtttgtgcc ggaaaccgtt tcgagaacta taagatgcag cccgtacagt acaagttcca
    19921 caaggacttt accggaaagc tttcttctta cggactctca gccgaacgcc gcgctccgaa
    19981 cggcatcaag gctgcggtaa tccgtgagaa gggtacgcaa tgcgagcgtg agaccgctta
    20041 cgccttgtat ctggctggtt tcgacgtgaa ggatgtccat atgacggact tggctagcgg
    20101 acgtgagact ttggaggatg taaacttcat cgtattctgc ggtggtttct ccaactccga
    20161 cgtattaggt tccgccaagg gctgggccgg cggtttcttg tataacgaga aagccaagaa
    20221 agcgatcgac aactattacg cacgtaaaga tacgttgagc atgggtatct gtaacggttg
    20281 ccagttgatg gccgagttag gcttggttta tccggagcac gagaaaaagc ataagatggt
    20341 tcacaatgat tcccataagt tcgagtctaa cttcgttagc ttggagatcc cgaaaaacaa
    20401 ctccgtaatg ttcggctcct tgagcggcac gaagttgggt gtatgggtag ctcatggtga
    20461 aggtaagttc gagttcccct acgaggagaa ggagtacaac atcatcgcta aatacaacta
    20521 cgatggctat cccgccaacc cgaacggttc tccttggtcc gttgccggtg tttgctcaaa
    20581 ggacggccgc catttagcca tgatgcctca ccccgaacgt gcgatcttcc cttggcagtg
    20641 cggttattac cccgccgacc gtaaggagaa cgacgaggtc actccatgga ttgaggcgtt
    20701 cgtgaacgct cgcaagtgga tcgagaataa taagtaaaaa taacaggggt tgtttttaga
    20761 gttctttgaa ccttaaaaac aacccttgtt tctatatctc cttaaagttt cttggtaacc
    20821 gccttttgat tgaactcatc cacacggtag aatagacttt acaacgaatc cacgatttta
    20881 atatccaagc cggtacaggg gggattatcg gtaactatta ctttatacaa ccgtaatatc
    20941 cctgcaacac cccgctaata tctttgcctc cgaaattaat agacacagaa tttaatagaa
    21001 gaatcatgga aaggttattt aaaatcagaa tctttacggt tatgttcttt ttagccgtag
    21061 cttctatagc agcgaacgct aaagaaagta agaaggaagg tgacaattat catgcaaagc
    21121 aaattctcat cgtaggtttg cacgataacg tgaaatcaaa ctatttctac aatgggatga
    21181 tcgccgaaga gaccggtatg aaagcggata gtatcgacca aacgtataat acgatcatcg
    21241 ccgagaatat cgccgcatcc gtaaagaacg gagattgcaa gtttattccg gcaaacgcta
    21301 cacaagtgac cggacaggta ctgaatgaga tcaaggttaa cggggagagc gaggattgct
    21361 attccgatct ttcagccgtg ccgaccgaag agttacaaaa ggtattggat aatgctgacg
    21421 ctgattatct gctagtatta aaccagcatt atcttaaatg gcaagaccaa cccttgcgca
    21481 cgcttttcca tatcgtcagc tataccttat tcgacaaaga taaaaatgag gtatataggg
    21541 ggaataactt ctttacctgc atgaatcttg agaacccgga taaactcaga aagagcagcc
    21601 gcaagagttc atccaagata gcatctacca ttatcaagac tttggacgag gactaacctt
    21661 cttttttata gacacattta taattttctc gttgagccta atggatatcc ttcattaggc
    21721 ttttttcttt atttaaacct acacacggat gtaatctctt tgcaaaaccg gacacttact
    21781 tttgcgccgt aaaagatatt taggtttaat tttaaaaaga ttattatgag gatgtttaac
    21841 aaacttacat gcaggctgct tgcctgtttg ttatttttta attgcttgcc ggctctcttg
    21901 tctgcgcaag gaacgcaagc gattatcacc ggtacggtca tggataataa aggggaatcg
    21961 gtgatcggag ccacgatcca agtcaagaat gaatctaccg gattcttcac gggttctatc
    22021 acgaacgata aaggagaata caccatcaag cagcttccgc taggttctcc ttataccgtt
    22081 acagcttctt atatcggtta tggagaacag aaaaagacag gatacgcatt gaaccaaggg
    22141 gatatgcttc gagtggattt caagctggcg gaggaatcgg tggaaataca agccgtcgag
    22201 gtagtcgcta attccttgaa gaacatggtt ccgaagatcg gtgcggcaac atctatctcc
    22261 gctcaaaata tcacgaagct tcctgtaaac ggccgtaact tcacatccct aatggatctc
    22321 tcgccattga gtagcggagg aaatatcgcc gggcaattat catcctcaac gaattacacc
    22381 atcgacggta tgacggctaa aggaaccgta gcgagcggaa cgacttccgg cgcttatacg
    22441 atatccatgg aagccgtccg cgaatttgag gtggtaacca atcaatatga cgtgaccaac
    22501 ggacgttccg ggggcggcac cgtgagcgct gtcacgaaat caggaaccaa tactttcacc
    22561 ggaagtgtat tcggattcgg tcgtgccgat tggttatcca gctcctatga tatacgggga
    22621 aataaatcga cttccgactt ctctacctat caatatggtt tctctttggg aggcccgatc
    22681 gtgaaagacc gtgcgcactt ctatgtcgta tgggatcacc aacaggattc ccgtccgatt
    22741 tatatagcgg atatcaagac ggcggcggac gagtctcgct ataatgtcac tcaatctacg
    22801 ctagaccgtt atctggatat cgcccgtact aaatacggag tctccaatga tcctcaattc
    22861 ggggagttcg gcaagaagaa gcagacgaac gcagtcttcg cccgtatcga ctggcagttg
    22921 aacgctacca acttgttaac cattcgcaat aatttcatca acgaggataa taaacagagc
    22981 gagagcgata actccagcat caatctttac gaggtttgga tcgatcgcaa atcgcataac
    23041 aacagtttac tcgctacctt acgctcggta ttaagcccga aactgactaa tgagttgaag
    23101 cttcaacatt tcttggttta cgaggctacg accccgaaca agcaattgcc tagttctaat
    23161 attccgagag caatcgtaga gaacgtggaa tctatttctg gtgacaagag catgtacact
    23221 tccatccaac ttggaggtca acgctacgct cccgaacatt ttaaggataa tgtacttcaa
    23281 ttggtagaca atatgtatta taatacggac cgcatcaact atacattcgg agcggacttc
    23341 atgtacacca atatgaaatc actctacggt agtgagatga acggacggtt ttatttcacg
    23401 ggactggata atttcgagca tatgactcct taccgctatg cccgggaaat cgccttggta
    23461 gatgatccta ccgtaaagat gaataccttg aactccgcta tctacggaca attacaaacg
    23521 aagcttttca ccggattcga ggtcatggcc ggtatccgtg cggattatac ccgttatttc
    23581 aaccacgcga actttaacca gactgtttat gacgaactag gcttacgtac ggacaacgta
    23641 atctccacct tccagttgca accccgcgtt caattcacgt gggacgtgaa tgataaacat
    23701 caagatatta tccgccttgg cgccggtatc ttcggttcgg atttaaacaa ctattccatg
    23761 atcaacaata tgctgttcga cggtacgaag gtagcgtccg tggatataca aggcaatttg
    23821 gttccgacac cgaatttccc ggcataccgc aaagatcctt ctaccgctcc gggcgttgat
    23881 ttattcaaca acccgaatat ccaaaagatc agcacgatca atatgaatag taaggatgcc
    23941 cgtgtaccgg tagtatataa gttgaacgcc agctacacgc atttcttctc cgatcgcttg
    24001 cgggtaggta tcagtgctta cgccaactgg gcacgccata attatatgta cgtagaccgt
    24061 aatatggtgg atgagcctta cttccgtatc gccgccgagg ggaatcgtgg cgtgttcgtc
    24121 cccgccgaga gtatcaatac caagaacgga gctaccgact ggatgcaagg acgtaaaagt
    24181 gataaggtag gccgtgtgct ggaattaatc agcgatggaa aaatcaacca atacgcattc
    24241 gtggtagatg gaacttggcg ttatttcaag gatggcgagc tttctttcag ctatacgtgg
    24301 aacgattcca aggataacac ctcttacaac ggtaacgtag cgaatacagc gactctagcc
    24361 ttgatggtaa aagatgatcc tcgtgatttg agtaccatga cttactcgga caaccaattc
    24421 cgccataagg tcgtattcta cggtacggct ccttctttct ggggaatcag cgtaggcttg
    24481 cgtttctccg ggatcggtgg aacccgctac tctttagcgg ttagtggtaa tatgaacggt
    24541 gatttcgtat catccaacga cttggcttat atctatgacc cgaacgatag taatacgcct
    24601 caatatcttc gtgagggtat ccaagcgatc ttggacaatc cggaagcgga gaagagcgta
    24661 aaagattata tccgtaaaaa ctatgggaag gttgccgagc gtaacggtgg cgtaaatggc
    24721 ttctacggta ctttcgattt gcgcttgaac aagaacttca agatctataa gactcattcc
    24781 atcgaggcct cgatagactt tttcaatttc ctgaatatgc tgaacaagga ctggggtgcc
    24841 ggacataatc taggcaagca gaatatctac tccatcaaga gttttgatgc ggagaagaag
    24901 caatacgtat ataacgtaaa caaaaacacg ggtgtatcca atatgaacgg aaacccttgg
    24961 cagattcaaa tcggcgtacg ttataaattc taactaacat attctatatt caaatcataa
    25021 aaaaaattac gatgaagaaa caattcttat cattcacgct tttacttgcg ttatccactt
    25081 ggatagcgca agccgctacc gtaagaggca ctgtatccga tacggcaggc aaaccgctac
    25141 aaggcgtagt cgttacggat ggttataatt tcacgcaaac aaatgagcgg ggagaatata
    25201 gcctagattc gaatctggac aaaagccgct ttgtctacct ctccgtaccg ggtaactatg
    25261 agatcgagca aacaaaaggt ataccggatc ttttctatca gcaacttgat aaaagtaagg
    25321 agatcaatga acatgatttt acgctcaccc ctaggaaaca gccaatcgac gggtttgtct
    25381 acttggcaat ctccgatcct cagaccatcg acgaacggca gatgaaacgt ttccgtgaag
    25441 agaccatccc cgacttgaag cagactatag agcgctacca aggaaaagag gtctacggta
    25501 tggcgctggg agacattact tgggatcgca tggatttatt cactccttat aaggaagcgg
    25561 tctcggtctt aggcatcccg atgttctccg tgatcggcaa tcacgaccac gacttacgtt
    25621 acccagcctt atccaatcaa aaggtaaccg aggagagcta tgcggagcgt atctacgagg
    25681 atcatttcgg cccttacaat tattcgttca atgtcgggga tgcacatatc atcaccttaa
    25741 aagatattga ttattataaa gacaagaaat atgacgaacg cttcggaaag gaacaactgg
    25801 aatggctgaa aaacgacctg agttacgtta aacccgggac acttgtattt atcaacgtac
    25861 atgccccggt attcaaccag acggataaag ggggaggaaa cgccgaggac gctgagagcc
    25921 tgaaagagat cgtcagccct tataatgtcc atatcttcgc tggacatacg catttcttcg
    25981 agaacaacca agtcacaccg aatctgtacg agcataatat cggagccgct tgcggagctt
    26041 ggtgggccgg ccatgtaaac cggtgcggca ccccgaacgg ttatctggtc gttgaggtga
    26101 aagggaatgc cgctacttgg tattataagg caaccggcca tgattcgaat tatcaattca
    26161 gggtttataa gccgaatgag ttcaaatcgc aagcggatta cctagtggtg aacgtatggg
    26221 attgggaccc gacctaccaa gttacatgga gcgaaaacgg catagagaaa ggtcgcatgg
    26281 agcaattcga tgatgaagac caagactata tcgacatgca cggaaaacct tccggatatc
    26341 atacatcgca cttattccgt tgccaccctt ctgccggagt caaagacgta cagatcaagg
    26401 ttatcaaccg atttggcgag acctttacta aaaatgtaac actcccgtaa tcaaatcgta
    26461 acaagtggca tttacttttg tatcgataaa atgtagaaaa ctctcattac atattaatgt
    26521 tagaatcatt acaaaggaac aaaccaaacc ttattcctaa ctttgaacgg caactcggct
    26581 ttcggcggaa ggcggttgcc gttatttttt tgagggtata tcccattctt aacgggaaaa
    26641 gtttcgagtt cattcgaaac ttttgtactt ttacgcaaaa gtttcgagta tggacgatag
    26701 atttaagaca ttagagaagt ataacctatg gggtggaaac gattttccaa caggctataa
    26761 acggcaagat tatttagata ggatattatc ctacaccgga aacagattaa tcaaagtctt
    26821 ggtaggacag cgacgtgtag ggaaaagcta tctccttcgt cagttagcta gccatctcgc
    26881 caatagtgga gtaaatcccc gaaatatatt cttcattaac tgtgagctat ccgccttcta
    26941 ttttttgaaa accaatgaag atcttgattc cctgtttaat ctctacttaa aacaaataaa
    27001 tcctcaaggt cgtatctatc tgttcattga cgaaatccaa aatgtagagg gatgggaacg
    27061 cttcgccaac tcatactcac aagactatac cgccgaatat gagttattca tcagtggttc
    27121 caactctaaa atgctatctg gagaactcgc cacgttatta gccggacgtt atgtggaatt
    27181 tgccatctat cctttttcat acacagagtt tcttggaatc acccaaaaag aaaacaacaa
    27241 ggtacactac ctagaatata tgcaaagtag tggtatgcct gaattatacc atctatctca
    27301 accagaagta caaagaaatt atatatccgc attaaaagac accgtattac tacgtgatat
    27361 catacaaaga caaaacataa aagacgctaa gttgcttgag gacatttttg tctatctggt
    27421 aaataacgca tctaatttaa tatcaattcg gaatatcacc aattatttca agagctcggg
    27481 aaggaagacc agctatgata cgatcgcctc ctacattagt tacatagagg acactttttt
    27541 ggtacataaa gtcgagaaat accaaatcaa gggaaaggag accatcgccg ggaattgtaa
    27601 gtattacatc aatgacctag gtttcaacaa ttatttatat caaggctttg gctacggcat
    27661 tgggtataaa ctagaaaacc tcatttatct agatttatta agggccggct atcaaatata
    27721 cgtaggcagc ataaagaaca aagaggtgga tttcgtcgct atcaaaggag agagggttat
    27781 ctatctccaa tccacttatt tactaatcga caaagaaacc atcgaacggg aatatgcctc
    27841 gttagaggcc attgaggata attacgagaa gatcgttgtc tcgctcgatg atctgccgct
    27901 tccttccaaa gaaggaataa agcacgtaca agcatggaat ttatcccatg ccattctcta
    27961 aaatcaaggt ttgttttcgg atctagccct tcctataagc tcacaaaaaa agcaccttgg
    28021 cattttgtca atttgtaaac tcaactgccg gagaatcact tttttcgggc aaacgtacag
    28081 cttatcccca aatacgagaa aaaatattag caatcatttg tcttataccg cattagttaa
    28141 aaacagcctt ttatcctagc gaatttaatt catcctaatt catatcctat agcttatccg
    28201 ggctatctca ttgagttacg acagggatat aacagggtta cgatgcccat tcatgagtac
    28261 taacaaccct attcatgact gtttacgatg cccaacggca ctactgtcgt tgccaaacac
    28321 gactagtcgc actgcctttt accacctatc gtgtgtaaaa agtggtcctt ttgcatgaaa
    28381 aaggctattt atacccctcc gatctcccct acttcatacc tctctcaaaa agggtatgtc
    28441 acgatatccc ccttatatca atcaaaaaga tcgaataccg tccatttcac caacaaagcc
    28501 cttatctacc cttatcaaca aataagggga aacagcgcaa tactgtctcc ccttgccttt
    28561 gatccgtttc catcctcacg gaagtactta cggatgaact ttaatttatt actttagtat
    28621 taatattaat ccattcccgc ttgttcgccc tctcggggta cttggataat ccgcacggga
    28681 atgattttcg atttatcttt tcattattcc tttacatgtc ttatttaacg accaccttta
    28741 cagtctcgtc gccaaccgtt acaagaacga ttccagcagg aacagcgatc gtagcgttat
    28801 cggaaatgac aactgtctct gccaacggca tacccaacaa gttgcgaaca taagccatct
    28861 cgccttgagc gccttggatc gttacggaac cggcgttgcc gatcactacg acagaagaag
    28921 acgcagagtt atcgatagac tcattagatg taggattacc ctcacctact gttaccggca
    28981 acgctttaga agtatcagaa gtaaagccta acttaccgtt caacgcatac aaatattttg
    29041 taggttggtc taccggtctc accgaataac cggcatccaa cttcgtgata taaaatttga
    29101 agttatttat acctccaagg caaacatctt ccttagcttc tgccgcaaca accacattct
    29161 ttccgtttac agttgtattg atcgtatcaa cacctgctaa agtagccgga cggaaaatgg
    29221 ctttaacatc tgtattctga tcagcttcag ctccataagt accttccaaa ccatagttct
    29281 cgtcataagt aaacttagct tgagcctcat tccaataacg taatgagtct tgagcgaaat
    29341 acaagaaatt tcttaccgga gcaacggagt caccttcagc gataccttta gagatataga
    29401 aagaaggaag ttctgccttg ctatccgccg tatccaacca gaaagtcaaa ccctccgcgc
    29461 caatgatacc ctcaaggata ccattcttgt tttccttcaa ggagattgaa ccttcctcac
    29521 tatccaatgt cgcatgtctc ggaacagcat ccaagctagc acccatctgg aagaaatcta
    29581 ccactacttt cgcataatcc gccttttccg caccaactag aacttcatcg aagctaggag
    29641 cattcacatc cactttcaac attttagcgt caggcttgac aactttatta taattatcga
    29701 cagcctcgtc agcgtcaaga gcctcatcca agcagattac ggaataagtg ccgtcaacgt
    29761 tcttcttgaa taccaagcga gaaagatagt ccgctttctt atcgttgtaa tcaaccaact
    29821 tatagtcgga actctcatgc ttcaaaccct tcttatcgtc aaccaaatag taagcttgaa
    29881 tagtcaacat atccgctttc ttcttagcca cctcgtcatc cttcaaatag atgtactcaa
    29941 cattattttt aacagcctct gccttctcca agctcttagc ggcatcactt accggctcaa
    30001 atttagaacc atcggtatta tagttcatat acactttctc tacggcaaca gaggactcgc
    30061 cattaaatac caactgagcc ttttgcttca attgagcgtc agaaagagcc aagaagccat
    30121 cattagcgct tacggcaact aatttgatat tctcggcagg aatatcacca accgaagtct
    30181 ttacggcttg ataaattcca gccttgtctg tcttatacaa attagcatta aacgtttcat
    30241 tcgtctcaag attcttaaac gtaacagcac cggaaccctg catacttaca attacccatt
    30301 gtgcaacagg agccttcaag tcaaccttag caggagccaa agcctcgtta gagaaagaag
    30361 cggtagcacg agcctcttca gttttcgcat acgtagaaac caaatattta ccatacaaag
    30421 actcaccttc ttcaccatcg gcaggtttag ttcctgtgaa gtagatatta tagatagcgg
    30481 caccgtcagt cttcaacaga tcagaagcct ttgcccatgt atttcctgta gtctgggcca
    30541 aggaaagctt atcagtggaa cccttcgtag tgatataagt cttcaaacca ccagtggtca
    30601 aggaataagc tcctacataa acagttaact ctgaaccaaa gttctcatct gtgcccttcg
    30661 ttaccttcac acctgtcatc ttgatcgtat attgaccagc cttgtttgcc aagtcatctt
    30721 cagaaacacc atagatagcg ttcatgaaag cgatcttacc gtctttctta acattggtag
    30781 cgttcagttt ctcgcccttt acggtagtga aaccgaaacc ctcaccttta gcagcatcca
    30841 agctcgtgat accgaaagta gcgttcgggt tcaatacgat gaaagtagcg gctttcaagt
    30901 tatctgcggt tacaccaccc tccttagcca acttcaaacc agcggcgtta gctacaacga
    30961 aacactcgcc ggaaacctca gtctcaccta actccaatgt agaattaaca gtagaagcgt
    31021 cgatagcgaa catctgctct ccaaacggat tcacgtcagc ctcggaagcg gcgttcggga
    31081 atttaaaaga gaacccctta ccggaaagat tgctgttcaa atcactagag gttgttcctt
    31141 ttttagcgat aagcattttt gctacatttg cggcagtagc catatcataa gccaaaggtt
    31201 tacctcctaa tgtaatttta tcatcattat agttatcatc ggtattattg tcatcataag
    31261 taaaccaaca ataacctttc ttcacatcat cctcgctagc ggcctcaaca aacgtggttc
    31321 cttccttacc ataaaccacc tttccagcag cgtctaccag tttaaacatc aatttaccat
    31381 tctcggtctt tacgcctgta accgtgaaga caccagcttc gctttctgta acggtattcg
    31441 caaacttata agcagcgtcc gtcactttcg ctgatttcaa gaaagatgta ccctcttcat
    31501 ttcccaaata gactttcaga ccttctgttg gcttagcttc cttctgagaa taagtagttc
    31561 catccgcagc aaacgccaca cctgccataa gcaagaacga cgcaaacata gtagaaattc
    31621 tcttgttcat aatctctaat ttaaatatta ataatagtgt taattaaata tctctcaact
    31681 ctttaattat ccttcgccat accaaaacga ctagtctaga ccatcattta gatcttgcgt
    31741 ttttgaagag ggaaaacggg aggtttgttt acggaa
//
LOCUS       DBMDTB010000038        31107 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_557_length_31107_cov_12.232503, whole genome shotgun sequence.
ACCESSION   DBMDTB010000038 DBMDTB010000000
VERSION     DBMDTB010000038.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 31107)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 31107)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31107
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_557_length_31107_cov_12.232503"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..581)
                     /locus_tag="ACZPB4_07945"
     CDS             complement(<1..581)
                     /locus_tag="ACZPB4_07945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase-related protein"
                     /protein_id="HIR1098188.1"
                     /translation="MLTAKEIRESFKQFFASKEHQIVPSAPMVVKGDPTLMFTNAGMN
                     QFKDIILGNVPRKYPRVADSQKCLRVSGKHNDLEEVGHDTYHHTMFEMLGNWSFGDYF
                     KKEAINWAWEYLVEVLKLNPERLYATVFEGSPAEGLDRDNEAAGYWEQYLPKDHILNG
                     NKHDNFWEMGDTGPCGPCSEIHIDLRSDEERAAV"
     gene            680..1663
                     /locus_tag="ACZPB4_07950"
     CDS             680..1663
                     /locus_tag="ACZPB4_07950"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M23 family metallopeptidase"
                     /protein_id="HIR1098189.1"
                     /translation="MKLFKSRKTYYLYNPNTLNYERVYPSSKDRLFTVLRHLSTGIAF
                     GVATFFVMMHLVDSPMESQLRKENRLLQTQYEVLSLRLNNALDVLDDIQQRDENLYRA
                     IFQAESIPESVRKAGFGGTNRYEHLMSLSNPELVVSTTQKMDMLRKQLYIQSNSLEEL
                     ISLGKNQEERSKCIPAIQPISNKDLRRTASGYGVRIDPIYRTPRFHSGMDFSAKVGTE
                     IYATGNGVVTFAAWKQGYGNCLIIDHGYGYQTLYGHMSKFKKRVGQKVTRGEVIGEVG
                     NTGKSTGPHLHYEVIVRGKHDNPSKYYYMDLSPEEYDRMIQIAENHGQVMD"
     gene            1678..2034
                     /locus_tag="ACZPB4_07955"
     CDS             1678..2034
                     /locus_tag="ACZPB4_07955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HIR1098190.1"
                     /translation="MSLKKNKDLKLYFSISEVAQMFDVNESTLRFWEKEFDIINPRKT
                     SKGTRFYKQEDIDAVRLIYHLVKERGMTLAGARQKLKDNKETTIRQEEIVNRLKQIKE
                     ELLAMKDAFDAFAPKV"
     gene            2114..2515
                     /locus_tag="ACZPB4_07960"
     CDS             2114..2515
                     /locus_tag="ACZPB4_07960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3127 domain-containing protein"
                     /protein_id="HIR1098191.1"
                     /translation="MEITGKIIQVLPEVGGVSKAGNEWKKQEYVLETHDQYPKKVCFQ
                     IFGADKIAQAAIQPGEELTVSFDIDSREYQGRWFTSINAWKVDRPMAAAPQAAPMGVT
                     PDNFAPASAPTAPASSAPDFGPANPIDDLPF"
     gene            2522..3472
                     /locus_tag="ACZPB4_07965"
     CDS             2522..3472
                     /locus_tag="ACZPB4_07965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="calcium/sodium antiporter"
                     /protein_id="HIR1098192.1"
                     /translation="MDIVLLIGGLLLILVGANALTDGAASVAKRFNISSLVIGLTIVA
                     FGTSAPELTVSVVSALKGSSDIAIGNVVGSNIFNALMIVGCTAAIVPISVTKGTLSKE
                     IPLCVLASIVLFICANDVLINGASHNSISSSDGMLLLCFFAIFLGYTFAIAHNGEENG
                     ESTIKIMPIWKASLFIIGGLAGLIYGGQFFVDGASGIARGLGVSESIIGLTLVAGGTS
                     LPELATSVVAALKKNPEMAIGNVIGSNLFNIFFVLGCSATITPMNIQGITNLDLGVMI
                     GSCVLLYIFGLFFKKRTITRPEGILLIACYIAYITYLIVG"
     gene            complement(3518..5803)
                     /locus_tag="ACZPB4_07970"
     CDS             complement(3518..5803)
                     /locus_tag="ACZPB4_07970"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008728 - GTP diphosphokinase activity
                     [Evidence IEA];
                     GO_function: GO:0008893 - guanosine-3',5'-bis(diphosphate)
                     3'-diphosphatase activity [Evidence IEA];
                     GO_process: GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RelA/SpoT family protein"
                     /protein_id="HIR1098193.1"
                     /translation="MDDTKDTKDIKETGEAASVLSADEQMIQDGFNALLNDYLKSNHR
                     RKVERITKAFNFANQAHAGVKRRSGEPYIMHPIAVARIVCREMGLGSTSICSALLHDV
                     VEDTEYTVEDIRDMFGDKIAQIVDGLTKISGGIFGEQASAQAENFRKLLLTMSDDIRV
                     ILIKIADRLHNMRTLGSMLPAKQFKIAGETLYLYAPLAHRLGLFSIKTELEDLSFKYE
                     HPQEYDFISAKLKATEESRNKLFERFAAPVDEKLKSMGLQYEMRARVKSVYSIWNKME
                     SKGVAFEDIYDIYAVRIIFDPLPGVDEKNQCWDIYSAITDIYRIRPDRIRDWVSRPKA
                     NGYQALHLTVMGPDGQWVEIQIRSRRMDDIAEKGFAAHWKYKESNVEEDTELDKWIQT
                     ITEILESPDPNALDFLDTIKLNLFTSEIFVFTPKGDIKTLPQGATALDFAYALHSDIG
                     NKCIGAKVNHRLVPLSHPLSSGDQVEVLTSRSQEPQPEWLNFVTTAKARAKIDAVLKR
                     VRKEVAKYGEIKVLDAFKRSELEASTSNLDKLGMYFGFSKREEFFYAVEKGDVVLPEN
                     LKKLLKEKTDNVLFKYVKQALGVASKKVKQPEEEEAKKEKPKYDKKKPYLLKEEAFER
                     NYVIAECCKPIPGDDSLGFINDDGNVVVHKRSCPIAMRLKSSFGERILNTVWSSHMNA
                     SFEATLEVKGIDSIGVLNTITKTISEDFNVNIMRLLIEAKDGVFEGKIKMKVHDVEDI
                     QKMCVTLSKIQNIKSVGRVAD"
     gene            complement(5901..6371)
                     /locus_tag="ACZPB4_07975"
     CDS             complement(5901..6371)
                     /locus_tag="ACZPB4_07975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010535401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HIR1098194.1"
                     /translation="MNVSDKLDKVDLQILRTLQDNARLTTKELAARVSLSSTPVFERL
                     KRLENSGYIKKYIAVLDAEKLNQGFVVFCSVKLVRLNKDIAFEFTRIIQEIPEVTECY
                     NISGDYDYLLKIHAPNMKYYQEFILNVLGTIDSLGSLRSTFVMDEVKHDYGIHI"
     gene            6540..7829
                     /locus_tag="ACZPB4_07980"
     CDS             6540..7829
                     /locus_tag="ACZPB4_07980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase family
                     protein"
                     /protein_id="HIR1098195.1"
                     /translation="MATKKLHFETLQLHVGQEQPDPATDARAVPIYQTTSYVFHNAQH
                     AADRFGLRDAGNIYGRLTNSTQGVFEARVAALEGGVAGLAVASGAAAVTYALQNIVRA
                     GDHIIAADNLYGGSFNLITHTLASQGITNTIINVNDLNALEAAIRENTKAIYVETFGN
                     PNSDVTNLDAVAEVAHRYHVPLIVDNTFGTPYLIRPIEHGADIVIHSATKFIGGHGSS
                     LGGVIVDGGTFDWKANADKFPTLAKPDPSYHGAIFADVAGSAAFVTRIRAVILRDTGA
                     TISPFNAFILLQGLETLSLRVERHVANALKVVDYLSKHPKVEKVNHPSLPTHPDHELY
                     NKYFPNGAGSIFTFEIKGGQEAAWKFIDSLEIFSLLANVADVKSLVIHPYTTTHSQMS
                     PEELAQQHITPSTVRLSIGTEYIDDIIDDLDQAFAKI"
     gene            complement(7932..8330)
                     /locus_tag="ACZPB4_07985"
     CDS             complement(7932..8330)
                     /locus_tag="ACZPB4_07985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098196.1"
                     /translation="MRKLIMAVAVLGMSATMNFAKAQCVNEYGNKEPFAVEFSRLSSY
                     LGLAPYQMEEVLNINDYFVQEQRKSLSKDLKRQDERLQKAVYGNLKLMKEALTADQYR
                     KYVILLNVTNNNNRLTGAVTFTDIYLAENK"
     gene            complement(8650..9405)
                     /locus_tag="ACZPB4_07990"
     CDS             complement(8650..9405)
                     /locus_tag="ACZPB4_07990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HIR1098197.1"
                     /translation="MRILIVEDETAAYENLADMLVTIDPTLEIMGNTESVQQTVRWLQ
                     ANPRPDLIFMDIHLSDGSAFAIFDQIEVEAPIIFTTAYDQYAIDAFKVNSIDYILKPI
                     KSEELKRALDKFSRWNHQDIIHYLSQLTQLSTTPKYKDKLLIPIKDKLLPISLKDVSC
                     FYTADKNTYVYLKSGNSYPYAKTLEQIISSLSPADFIRANKQFIISRDSVKDITIWFD
                     SRLLVTLDIEVPERIYISKNKASEFKSWIVSLE"
     gene            complement(9412..10470)
                     /locus_tag="ACZPB4_07995"
     CDS             complement(9412..10470)
                     /locus_tag="ACZPB4_07995"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1098198.1"
                     /translation="MIFYSFVYEKRYNRMGSLDEKISVVKAKPWLVSLVCAVFIAYPN
                     LAWIFCDMSYLAPNDHQGFLLFFGFRFLYFWGLIWFLLKSNLRHEDCTSFFERLLWNA
                     LYVSGGFVVYKLISFLTISYDRFLSIIIFQFIVLALLCTLIGYIQMLYHNQREKDQLI
                     ENLRVENLQSRCDALVNQINPHFFFNSLNGISSLIRKKNDENTLLYVTKLSDIFRYIL
                     QSDKKNLVPLSEELAFIEAFQHVMVVRFANKLTFTIEVPEDKRNLRIPVLSLLPLVEN
                     VTVHNIIDSEHRMDILIRLNERMELVVSNPIYPKLTLPDTNGTGLKNLENRFLLLMNK
                     QIRVESDEDEFQVYLPLK"
     gene            complement(10538..12094)
                     /locus_tag="ACZPB4_08000"
     CDS             complement(10538..12094)
                     /locus_tag="ACZPB4_08000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008933 - peptidoglycan lytic
                     transglycosylase activity [Evidence IEA];
                     GO_process: GO:0000270 - peptidoglycan metabolic process
                     [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HIR1098199.1"
                     /translation="MKRYLLALICLNCLVSLVYAQEETRIEEKDTLSSLESEVGLIPE
                     SLDANVDSLLRTWHVQYFSKREDFCHDDDENVYFPDSVYIDRLSRLPSVIALPYNNIV
                     RDCIDLYAERKRNLVRYMLGMADFYFPIIEQVLDEHDLPIELKYLAVVESALNPVALS
                     RVGACGLWQFMLPTGKSYGLEINSLVDERRDPLKATEAACKYFKDMYAIYGDWNLVLA
                     SYNCGPGNVNKAIRRSGGKTDFWDIFPYLPKETRSYVPLFIAANYVMNYYCEHNICPM
                     QTSLPLATDTVMVNNALHLQQVSDLLQVDIETLRALNPQYKRDIVPGNTRPSVLKLPA
                     AETYAFIDKEDTVYTHRIEELLANCISANNSNGSLPSGATREKITHVVLSGENLYTIA
                     NRYGVTAKDIRKWNGLGSNRVAKGKRLRLYVDNGGVAFASATKTPVKSTTVTAKSTAT
                     TTKKSASAATKQIASANKDFVSYKVKSGDSLYSISKKYPGVTASSLQKVNGLSSPDIR
                     PGQVLKIPVG"
     gene            complement(12100..12810)
                     /locus_tag="ACZPB4_08005"
     CDS             complement(12100..12810)
                     /locus_tag="ACZPB4_08005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5683 domain-containing protein"
                     /protein_id="HIR1098200.1"
                     /translation="MRNRIILLLIGFMCYAGMGNAQEDKTEKAVPAIVSDSVEVAAPD
                     STVQAVLMAADSVGVPEVKMKLAFKPNPTKAVLFALVPGLGQIYNRKYWKLPIVYGGL
                     MGCMYAVTWNNKNYKDYSTAYKDIMYDAAKNLENPDAWSKSWQDLTSMAPEDAINNSN
                     FKDQLKRQKDYFRRYRDLSIIITVGVYALSIVDAYVDAQLFDFDISPDLSLHLEPVVS
                     PKTSVTPRTYGLNCSLKF"
     gene            complement(12807..13694)
                     /locus_tag="ACZPB4_08010"
     CDS             complement(12807..13694)
                     /locus_tag="ACZPB4_08010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HIR1098201.1"
                     /translation="MAALKRSALGRGLDALITMDDLKTGGSSSISEIELSKIQPNPEQ
                     PRSIFEEETLEELATSIRSLGVIQPITLKEIGPEQYMIISGERRYRASLKAGLERIPA
                     YIKTAADENVVEMALIENIQREDLNSIEIALAYQKLIDNYGLTQEGLSERVGKKRATI
                     ANYLRLLKLPAEIQVGLKDKKIDMGHARALIPVDDPEVQLALYEQILAQGLSVRNVEE
                     MVRNIAEGIQPELPEKKKSDRKPILPEEFKLLKDHLSRYFNTKVQLTCNEKGKGKITI
                     PFATEEELEQLIGLLDKLK"
     gene            complement(13682..14461)
                     /locus_tag="ACZPB4_08015"
     CDS             complement(13682..14461)
                     /locus_tag="ACZPB4_08015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HIR1098202.1"
                     /translation="MGKIIALANQKGGVGKTTTTINLAASLAALEKKVLVVDADPQAN
                     ASSGLGVDIRNVELSIYECLVNGEDASGAITQTEVEGLDIIPSHIDLVGAEIEMLNLE
                     NRERILKQILTPLKEKYDFILIDCSPSLGLITVNALTAADSVIIPVQCEYFALEGISK
                     LLNTIKIIKSKLNPALEIEGFLLTMYDSRLRLANQIYEEVKRPFRDLVFTTVIQRNVK
                     LSEASSYGKPVLLYDADSKGSINHMQLAQEIVEKNKGLWQH"
     gene            complement(15275..18589)
                     /locus_tag="ACZPB4_08020"
     CDS             complement(15275..18589)
                     /locus_tag="ACZPB4_08020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6383 domain-containing protein"
                     /protein_id="HIR1098203.1"
                     /translation="MNKKFSTLLAGAAFLSAVSVNSVYAQGVQDNSLPTEASAYPIVK
                     LAEGTNTGLFQLRIKDSDKVLSMDKDGKLTLVNVTTSSQLANTLWCVTVTSENQGQTH
                     KYDFMNKGTGMMLDITMSDIVGAEESTPVIPTTGGEISGWAFSREINKLEPERPLFSH
                     FSADSIVGFSVKTNDDKVYVQKEGAKKAETAGFAKFTLQAPGQIYLSAEELNTIFGVQ
                     KEDAGVKLTFNKDVLGTTLTNPFNANKFLAEESGDTKYLYISDLKKEAYLRVDTAYTN
                     ESGTKFLAYNWTKKGKTGEAIDAVRGSKIQDQHKFAFLYSPAYDSLYIYVHSITWNET
                     KANWETLVKKPEATGDNWRVSLQDLIKNQTRILTVDAKEQNTHISFGNMDCNPVASTK
                     TSVADGVYLIKSAKTGKYLAIPLHNDTTWVNNVEKANTAEWASLDLQDANHMPAYQWV
                     VLKKNAVDKNNISPIDAWNREYNTVTLSSVQLNKNVGGKYFYITTNAGTVLAGDSLEL
                     IAVDKKFYSDKYLGYKNLTKDELMVNKYTFNYWHPYAADKYIAVMKDSTMTVKDGKTP
                     FTIKTTGKEHKYGYDASLVNGEKGRIPGLAQLVRTMYQVSYDGAIFGSYAEAKENKYT
                     VSKLHQTTDSVYFKENNCIAREEGATVAHYYAIVEADVDGVIRNYKAGVSDYDASASL
                     KAQTLKETRTSAFYIAPDNTPLYRRFNNTLVGENANDAADSLYFVESIRKEYLMDENN
                     TNLQHSTVDYAGIWNKDKANGKLAFRVDTAWLKRGAGEIKPQYLISAFQDVIAGEKII
                     PCTEDGKHIKPDGTPTENPYECVHAVHVKTPAFVYGKYLVNFSDSAVACKADVNPFIF
                     NTKAVSNSSYTRVGFVPAVQYGDTLLVLTGKYANMTKEQLKNEGIESMIATYKKEYPS
                     FINDLRGDKHKNVTWSFRYVNPDLAAISYVDGKEGENNSFLIESNVYDKAHDTQYQTV
                     NGDATQAIAPKAAAAWLKMHNGCLVLTDVNATFDNAKTGGDGALVFNAFQKTEEEDMV
                     TSNDEIATEGVSVVAGNGTVTVQGAAGKSVVITNILGKVVAETVLTSDNATIAVPAGI
                     VAVAVEGEEAVKTIVK"
     gene            complement(18940..19692)
                     /locus_tag="ACZPB4_08025"
     CDS             complement(18940..19692)
                     /locus_tag="ACZPB4_08025"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004077 - biotin--[biotin carboxyl-carrier
                     protein] ligase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HIR1098204.1"
                     /translation="MMSTDNESPRILRVAETASTNSLLRELVIKESLAEGSVVVADFQ
                     TAGRGQIGNTWESEAGKNLMFSLVLYPTCIPANRQFLISQIAALSVKEALDLYADHIT
                     VKWPNDIYWKDKKICGMLIENDLSGHNLYCSIIGIGINLNQTVFRGDAPNPVSLFQII
                     GKEVDREEVLHRFLSIFYRYYLSLLQEEHEDIRARYQSALYRREGYHGYKDESGEFEA
                     CIHDIESTGHLLLALRDGSIRRYAFKEVSYCK"
     gene            complement(19679..20038)
                     /locus_tag="ACZPB4_08030"
     CDS             complement(19679..20038)
                     /locus_tag="ACZPB4_08030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HIR1098205.1"
                     /translation="MNIEEVREYCLSLKNTIECFPFDEVSLVFKVENKMFLLLPLDAE
                     EPHVSLKCSTDYVEELREHYTAVEPAYHFNKKYWNSIYLDRDMEDEEIKRWIFHSYRE
                     VIAKLPKNIREIYNDEH"
     gene            complement(20051..20416)
                     /locus_tag="ACZPB4_08035"
     CDS             complement(20051..20416)
                     /locus_tag="ACZPB4_08035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YraN family protein"
                     /protein_id="HIR1098206.1"
                     /translation="MARQNDMGREGESEARAYLVKHGYNVLHTNWHWHHYELDIIAVK
                     EDELIVVEVKTRSEDFLLSPEDAVDTKKIRRIVAAADAYVRYFNIDLPVRFDIVTLIK
                     KETGFLIDHIEDAFYAPCR"
     gene            20486..20713
                     /locus_tag="ACZPB4_08040"
     CDS             20486..20713
                     /locus_tag="ACZPB4_08040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098207.1"
                     /translation="MKEERKYSSAHPNHPRVHKVTFMLNDEEHKAVKRYLSRYKIENK
                     SRWYRETILSHILKTLEEDYPTLFNENEMRR"
     gene            20710..21150
                     /locus_tag="ACZPB4_08045"
     CDS             20710..21150
                     /locus_tag="ACZPB4_08045"
                     /EC_number="3.5.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0019239 - deaminase activity [Evidence
                     IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HIR1098208.1"
                     /translation="MNPFNDEYFMKQALVEARAAASEGEVPVGAVIVCNNQIIARAHN
                     QTECLNDVTAHAEMLAITAAAGVLGAKYLTNCSLYVTVEPCIMCAGAIGWAQLSTIVY
                     GASDDKRGFSKFAPQAFHPKAIIKKGILEKECAEEMQRFFKQRR"
     gene            complement(21154..21432)
                     /locus_tag="ACZPB4_08050"
     CDS             complement(21154..21432)
                     /locus_tag="ACZPB4_08050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4834 family protein"
                     /protein_id="HIR1098209.1"
                     /translation="MFKFLFVIFFFFILLVFLMGFSILRTFKNIFFGSGNSTRKGEQR
                     RQTNSNTSGHRSTTTTARDDDDDRTPYVHRKKIFAKDEGEYVDYEEVK"
     gene            complement(21489..22190)
                     /locus_tag="ACZPB4_08055"
     CDS             complement(21489..22190)
                     /locus_tag="ACZPB4_08055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HIR1098210.1"
                     /translation="MSIRKHIPNTITCLSLLSGCVASVMALHGNLLSALIWIIIAAVF
                     DFCDGFAARLLKAYSPMGKELDSLSDMVSFGFAPGMVVYWLLGEASTALPFGSLNTYI
                     PYLAFVIPTFSGLRLAKFNIDERQTTSFIGLPVPAHALFWASVGYSVLPVIHANEGLF
                     VLVTVILAFITSLLLVSEIPMFSLKVKSLAWKGNELRYILIACAIIFVALWGFLGISG
                     TILLYIVLSIFNKKG"
     gene            complement(22187..22849)
                     /locus_tag="ACZPB4_08060"
     CDS             complement(22187..22849)
                     /locus_tag="ACZPB4_08060"
                     /EC_number="4.1.1.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004609 - phosphatidylserine decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylserine decarboxylase family protein"
                     /protein_id="HIR1098211.1"
                     /translation="MKVHKEGTGLLLTLFTILFIVNITLYHTVGKGMLFYSVAFVSTV
                     LFLLVLNFFRSPFRRFPYDSEGLVIAPADGTIVAIEEVMENEILHKKCLQISIFMSIF
                     NVHANWFPVNGTVKHVSHQNGRFMAAYLPKSSTENERSAVVITTRNGVDVLARQIAGA
                     MARRIVTYAKPGEKCHVDEQMGFIKFGSRVDVYLPVGTEVLIEMDQKVTGNQTPIARL
                     SK"
     gene            complement(22922..26089)
                     /locus_tag="ACZPB4_08065"
     CDS             complement(22922..26089)
                     /locus_tag="ACZPB4_08065"
                     /EC_number="3.1.11.5"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HIR1098212.1"
                     /translation="MLTIYRASAGAGKTHKLTGEYLMLLFSQPGAYRRILAVTFTNKA
                     TDEMKTRIVQELYHLASGRASDYIQLLSSAYSLTERQVREQARKILVAILHDYSAFNI
                     STIDRFFQQTMRAFTREIGLQGGYGIEMDQELVLTEAIDNLLADLEKPESKDLLGWLL
                     RFAENKIEDGGGWSLRQDIMSLSREVFKESYKAFSEEVGKDIADKQALDAYKNELYAI
                     IRSVEAEAKRLGEEGVALLKQFALQPSDFKGGSRSPFFYFEKLAKGEMKEPTATFQAL
                     PDNPDAYTTKTTPPGLRQIIGCVYEEGLNACVKNIVSLFANLTAYNTAREIVRYYYTL
                     GILTDISRQIAFYREEKNVMLIADTTELLNKVISGSDAPFIYEKTGTHVDHYMIDEFQ
                     DTSGMQWNNFRPLVEESLANGRANLIVGDVKQSIYRFRNSDWKLLDEQVRRDFEDEQV
                     REDTLKDNWRSCRHIVEFNNAFFTAAPAILQDLYNEALKNSSLSEEERTAFSARIMAA
                     YDDSSQRVPPPFQKKDGHVRIDFLSGDEDKDWKQEAMERLPATLERLQDSGYALKDIA
                     ILVRTNQEGALVADTLLAYKEEHPSDRYNYDIISDDALFVGSSPAVRFLIAVLRYLRN
                     PEDRTNRKLAMYAYQVLTGKFGESEADESVFQNLQSISRQSLYEVTEGLFRNFSAYFP
                     ETEQVFVQAFLDMVSEYAQKESADLNRFLRWWDETGYRKTIATPDGQNAIRILTVHKS
                     KGLGFKVVIIPFGDWEIDHKPTKPVILWCHPEKKPFDRLHLVPVRYGQILSSTIFAKD
                     YFKERLHAFIDNLNTLYVAFTRSKEELIVFSPRPRKINKEGKVEKITSIADLLWAGVE
                     TDIEDDTFERGEWWHPASGRTAEDTLEEIPMSRLYSVSPDDRLQLRLHGKGFFFDNAR
                     RKHGTLMHEVLSRIRTPKDIPASVESYRLAGVINREEAAELISRLEELLQAEEVKAWY
                     DGSARVLNEVDILFGKGLSKRPDRVIIKGGKVIVVDYKFGERQDKRHPNQVRNYLQLI
                     RKMGFERVDGYLWYVELGKIEAVNK"
     gene            complement(26102..26446)
                     /locus_tag="ACZPB4_08070"
     CDS             complement(26102..26446)
                     /locus_tag="ACZPB4_08070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor"
                     /protein_id="HIR1098213.1"
                     /translation="MKNNDWKDRLGVMYSTNPDFQYNTGDTEEEDTLPKEKQALRISL
                     DKRNRGGKMVTLITGFRGTSEDLTALGKLLKVKCGVGGSAKDGEIIIQGDLRAKVLDI
                     LRKEGYSKSRTI"
     gene            26657..28966
                     /locus_tag="ACZPB4_08075"
     CDS             26657..28966
                     /locus_tag="ACZPB4_08075"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1098214.1"
                     /translation="MRNIILFIFIILTVHLNMSARGSGEKPSIVVLHSINFEESWTKQ
                     TYLDIERKFGEEGFTVKAIPLQIPGIRTMEGFQEKRTMILERVPVPPTLVVCIGDPSW
                     LVARPLFDKEWKDIPSIICYARDYMYPKEEYLIDLDKNVLDTLVPITDVVKDYNATFI
                     KYPVYIKQTIELIKKLQPELTKLAFIFDRRYISQQTKADVEAVLRKDFPGIQFEPLST
                     TSISTENLLDRLASFDNKTGVLYYSWYRTRKDNENRYLVDNVQKMTNSFSVPPIFTLQ
                     DVQTENGNFAGGYYVSPEDYAQVTVNTIEMILSGKDSKEIPIQTAETPRAYLNYQHLL
                     LHQIDPGLYPPNATYFQEPPGFLQKYKIHIISLLVILALLITIGILRVRLFIQKQKAK
                     DKELQIARQAQDLNQKYQLVLKASNMMTWIWDVKEARLECNNIYLTQRSIRDKGTDGQ
                     FCMSADEFYSGIHPEDLEQMQDAINKLIAGESISIDEEIRYLDDTGLEYTWIEIFAIV
                     GKTDPEGKPAYLTGGTTLINQRKKMEQELRDKEKIEESNRLKSAFLANMSHEIRTPLN
                     AIVGFSNLLAETCHSEETREFCEIIETNNELLLQLVNDILDLSKIEAGQMDFIYSEFN
                     VSTLFRSLYQTFQSRVKDGVTLYCEIPEQDCVIYSEKNRLTQVITNFLTNACKFTFQG
                     SIRMGYKEREDGLYFYVKDTGKGIERKNLPHVFERFAKFDSFIQGTGLGLSICQTILE
                     NLHGKIGVESEEGKGSTFWFTIPCAVSRP"
     gene            complement(28935..29420)
                     /gene="ispF"
                     /locus_tag="ACZPB4_08080"
     CDS             complement(28935..29420)
                     /gene="ispF"
                     /locus_tag="ACZPB4_08080"
                     /EC_number="4.6.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008685 - 2-C-methyl-D-erythritol
                     2,4-cyclodiphosphate synthase activity [Evidence IEA];
                     GO_process: GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 2,4-cyclodiphosphate
                     synthase"
                     /protein_id="HIR1098215.1"
                     /translation="MKIRVGFGYDVHALVPDRELWLGGIKIEHTLGLLGHSDADVLIH
                     AICDALLGAANMRDIGYHFPDTAGEYKNIDSKILLRDTMRLLREAGYELGNIDATVAA
                     ERPKLNPHIPLMKKTLAEVMNVDEEDISIKATTTEKLGFTGRQEGISAYATVLIQRMG
                     S"
     gene            complement(29427..30629)
                     /gene="porV"
                     /locus_tag="ACZPB4_08085"
                     /gene_synonym="lptO"
     CDS             complement(29427..30629)
                     /gene="porV"
                     /locus_tag="ACZPB4_08085"
                     /gene_synonym="lptO"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IX secretion system outer membrane channel
                     protein PorV"
                     /protein_id="HIR1098216.1"
                     /translation="MVRVSRFSLLLAVFSFLTAFTALYAQGGADDVKHKFAPINTAIP
                     SLSIAPDARGGAMGDNGVATTPDVNSQYWNPAKYAFSYSKAGVALSYTPWLRKLVNDV
                     ALAYLAGYYKLGDSDMQAIGASLRYFSLGEVQESRDGGMGNQLILNPYEMAFDVSYSR
                     KLSDVFSMAVALRYIRSDMGASSDADMVPDNAFAADIAGYLEKYVILGNSECLWSFGF
                     NVSNIGTKVSYDGGNTNQFLPTMLKVGTGLLYPIDDYNQIGIYVDLSKYLVPTEPIQE
                     GTTPEDEAAYKEKHDEYNNMSPITGIFKSFGDSPNGFKGELEEIMASIGLEYNYNQQF
                     FVRGGYYYENKYQGNRQYFSVGAGFRMSVFQLDAAYLISTVQSNPLDQTLRFSLSFDM
                     DGIKNLFR"
     gene            complement(30721..>31107)
                     /locus_tag="ACZPB4_08090"
     CDS             complement(30721..>31107)
                     /locus_tag="ACZPB4_08090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0031240 - external side of cell outer
                     membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="T9SS type A sorting domain-containing protein"
                     /protein_id="HIR1098217.1"
                     /translation="EFKVWDILNNSTTYTFTFEVAEGLKPNLIEMYATPNPARDQVEF
                     FLHHNRPESNLKVTVMVYDMTGKFLWSTEKSGSSELFKAYIVTWNLTDNGGRRLRPGV
                     YLYRAAISTNNSKEATKANKLIILAQ"
BASE COUNT         8935 a         7715 c         6153 g         8304 t
ORIGIN      
        1 accgccgcac gctcctcgtc cgaacgaagg tcgatatgga tctcggaaca gggaccgcaa
       61 ggacccgtat cccccatttc ccagaagtta tcatgtttgt taccgttcag aatatgatct
      121 ttcggtaaat attgctccca ataaccagca gcttcgttat cacgatctaa gccttcagcg
      181 gggcttccct cgaatacggt ggcatataaa cgctccggat tcagcttcaa tacctctacc
      241 aagtattccc aagcccagtt gatcgcctct ttcttaaaat aatctccgaa cgaccagttt
      301 ccgagcatct caaacatcgt atgatgatag gtatcatgtc ctacctcctc taaatcgtta
      361 tgcttaccgc taacacgaag acatttctga gagtccgcga cacgaggata cttacggggc
      421 acgttgccca agataatatc tttaaactga ttcattcccg cgttcgtaaa catcaacgtg
      481 gggtcaccct ttaccaccat tggagcggaa ggcacgatct ggtgttcctt agaagcgaag
      541 aattgcttga aggattcacg gatttctttt gctgtcaaca taatctattt atatagttct
      601 cgttaatatt ctgaaaaaca atttgcaaaa gtactgcaaa ttattatttt tgcgtgcatt
      661 cagataacaa aaaatgtaga tgaaactctt taaaagtcgc aaaacatact atttatacaa
      721 tccgaacact ctcaattatg agcgtgtata cccatctagc aaagaccggc tgttcaccgt
      781 tctccgccat ttaagcaccg gaatagcatt cggcgtagcc acttttttcg tcatgatgca
      841 tttggtggac tctccgatgg aatctcagtt acgtaaggag aaccgcctat tgcaaactca
      901 atacgaggtg ctttcccttc gcttaaataa cgcgttggac gtattggatg atatccaaca
      961 gcgtgacgag aatctgtacc gggctatctt ccaagctgag tctatacccg aatccgttcg
     1021 gaaagccggg tttggaggga caaaccgtta cgagcatttg atgagcctgt ccaatccgga
     1081 gcttgttgtc tccacgaccc aaaagatgga tatgctacgt aagcaattat atatccagtc
     1141 caactccttg gaggaactga tctccctagg aaagaaccaa gaagagagaa gtaaatgtat
     1201 cccggctatc cagccgattt ccaataagga tctgcgtcgt accgcttccg gctatggcgt
     1261 gcgtatcgac ccgatttacc gtacacctcg tttccattct ggaatggatt tctcggctaa
     1321 agtgggaacg gagatctacg cgacaggtaa tggcgtagtc acttttgccg cttggaaaca
     1381 gggatacgga aattgtttga ttatcgatca tggctacggc tatcagacgt tatacggtca
     1441 tatgagtaag ttcaagaaac gtgtcggaca gaaggttact cgtggagagg tgattggcga
     1501 ggttggaaat accgggaaat ctaccggccc tcacttgcat tatgaggtaa tcgtacgagg
     1561 aaagcatgat aatccgtcca aatactatta catggatctc tcacctgagg aatacgaccg
     1621 tatgatccag atcgccgaga atcatggcca ggttatggat taaacttcat tagcagtatg
     1681 agtctaaaaa agaataaaga tctcaagctc tatttttcca tcagcgaggt ggcgcagatg
     1741 ttcgacgtga acgagtccac ccttcgcttt tgggagaagg agttcgatat catcaatcca
     1801 aggaagacga gcaaaggtac ccgtttttac aagcaggagg atatcgacgc ggtacgcctc
     1861 atctaccatc tggttaaaga gagagggatg accttggccg gcgcacggca aaaactgaag
     1921 gacaataaag agacgacgat ccggcaagaa gagatcgtaa accgcctgaa acagatcaaa
     1981 gaagagctgt tagctatgaa agacgcattc gatgcttttg ccccgaaagt gtgattattc
     2041 tgttgataaa accagaacaa aaccgtacct tcgtccccaa ttaaataaaa cataagcaaa
     2101 taaaatacaa gacatggaaa ttacaggaaa aattattcaa gtcctaccgg aagtaggcgg
     2161 tgtcagcaaa gccggaaacg aatggaaaaa acaagagtac gtattagaga cacacgatca
     2221 atatcccaag aaagtatgct tccagatatt cggagcggat aagatcgctc aagcggccat
     2281 tcagccgggc gaggaattga cagtctcttt cgacattgac agccgtgagt accaaggccg
     2341 ctggttcacc agtatcaacg catggaaagt agaccgtccg atggcggcag ctcctcaagc
     2401 cgctccgatg ggagtaactc cggataattt cgctccggct tccgctccta cggctccagc
     2461 ctcatccgct cctgatttcg gaccggccaa tccaatcgat gatttgccat tctaaagact
     2521 aatggatatc gtattactaa ttggcggttt actactaatt ttagtcgggg ctaacgcctt
     2581 gacagatggt gccgcctcgg tagccaaacg cttcaatatt tccagcttag taatcgggct
     2641 aactattgtg gcgtttggga cttccgcacc ggaattaacg gtcagtgtcg tatccgcctt
     2701 gaaaggaagc tcggatatcg ctattggtaa tgtagtagga agcaatatat ttaacgcctt
     2761 gatgattgtc ggctgtacgg ccgctatcgt accgatcagc gtcacgaaag gtacgttgag
     2821 caaagagatc cctctttgcg tgcttgcctc aatcgtatta tttatttgtg cgaatgacgt
     2881 tttgatcaac ggcgcatcgc acaatagtat cagtagtagc gatggaatgt tactattatg
     2941 cttcttcgcc attttccttg gctatacatt cgcgatcgca cataatggag aggaaaatgg
     3001 agagagcacg attaaaataa tgcccatttg gaaagcgagt ttattcatca ttggtggatt
     3061 ggctggtttg atttacggag gacaattttt cgtggatgga gcttctggta tcgcccgtgg
     3121 actgggtgtc agcgaatcta ttatcggttt gactttagtg gccggaggaa cctctcttcc
     3181 tgagttagcg acttccgtcg tggccgcatt aaagaagaac ccggagatgg cgatcggaaa
     3241 tgttatcggt tccaacctct tcaatatatt cttcgtatta ggttgtagcg cgacaatcac
     3301 gccgatgaac atacaaggca ttaccaatct ggatttgggc gtcatgatcg gttcatgcgt
     3361 attgctttat atttttggcc ttttcttcaa gaaacggacc atcactaggc cggagggaat
     3421 cctattgatc gcttgttata tagcttatat aacttatttg attgtcggct gataaagctt
     3481 ttataaaaca aaagtgtagc gaagcacttc gctacactta atccgctaca cgtccgacag
     3541 atttaatatt ctgtatcttc gacaaagtca cgcacatttt ctggatatct tctacgtcat
     3601 gaactttcat ctttatctta ccttcgaaca cgccgtcttt cgcctcgatc agcaagcgca
     3661 tgatgttcac gttgaaatcc tcggaaatcg ttttcgtgat cgtattcaat acgcctatcg
     3721 agtctatacc tttcacctct agcgtggcct caaaagaagc gttcatatgg ctgctccaaa
     3781 ccgtattcaa gatacgttcg ccaaagctac ttttcaagcg catggcgatc gggcaggaac
     3841 gtttatgaac tactacattt ccatcatcat tgataaaacc taaagagtca tctcccggaa
     3901 tcggcttaca acattcggca attacataat tacgctcaaa agcctcctct ttcaataaat
     3961 aaggcttttt cttatcatat ttaggcttct ctttcttggc ttcctcctct tcgggttgtt
     4021 tcaccttctt ggaagcgaca cccaacgcct gtttcacata cttaaacaag acattatccg
     4081 tcttctcctt caacagcttc tttaaattct cgggcaaaac cacatccccc ttctctaccg
     4141 cataaaagaa ttcctcgcgt ttcgagaatc caaagtacat gcctaattta tccagattgg
     4201 atgtactcgc ctcaagctcc gaacgcttga aggcatcaag aacttttatc tctccatact
     4261 tagcgacctc tttacggaca cgctttaata cggcatcgat cttcgcacga gccttagcgg
     4321 tagtcacgaa attcaaccac tccggttgcg gctcctgaga gcgggaagtc aagacctcca
     4381 cctgatctcc actggacagc ggatgactca atggcaccaa acgatggttt accttagcgc
     4441 caatacattt attaccgata tcggagtgaa gcgcataagc gaaatccaag gcggtagccc
     4501 cttggggcaa tgtctttata tctcctttcg gagtgaaaac aaatatctcg gaagtaaata
     4561 agttcagttt gatcgtatcc aagaaatcca gcgcattcgg gtccggactc tccaatatct
     4621 cggtaatggt ttgtatccat ttatccaatt ccgtatcctc ctccacgttg gattccttgt
     4681 atttccaatg ggcagcgaag cctttctctg cgatatcatc catacggcgg ctacggatct
     4741 ggatctctac ccattgtcca tccggtccca taacggtcag atgaagcgct tgataaccgt
     4801 tcgctttcgg acggctcacc caatcacgga tacggtcggg acgaatccgg taaatatccg
     4861 taatagccga gtagatatcc caacattgat ttttctcgtc cacaccggga agcgggtcaa
     4921 aaataatgcg gaccgcataa atatcataaa tatcctcgaa agcgacaccc ttgctttcca
     4981 tcttattcca aatggaatag accgatttca cacgggcacg catctcatac tgaagtccca
     5041 tcgatttcag cttctcgtcc acaggggcgg cgaaacgttc gaataattta ttacggctct
     5101 cttctgtcgc tttcaactta gcgctgatga aatcgtattc ttgcggatgc tcgtatttaa
     5161 aactcaaatc ctccagttcc gtcttgatcg agaagagacc cagacgatgc gccagaggag
     5221 catacaaata aagagtctca cctgcgatct taaattgctt ggcgggaagc atggaaccca
     5281 aagtcctcat attatgaaga cggtctgcga tcttgattag aatcacccgt atatcgtcac
     5341 tcatagtcag cagcaactta cggaagttct cggcttgagc cgaggcctgt tccccaaaaa
     5401 tgccaccgga tatcttcgtc aagccatcca cgatctgggc gatcttgtct ccgaacatat
     5461 cccggatatc ctccaccgta tactcggtat cttccacgac atcatgcaat aacgcagagc
     5521 aaatagaggt agagcccaaa cccatctccc ggcatacgat acgagccacg gcgataggat
     5581 gcattatata aggttcgccg gaacgccgtt tcactccggc gtgcgcttga ttggcgaaat
     5641 taaaagcttt cgtgattcgt tcgaccttac ggcggtggtt tgacttcaaa taatcgttca
     5701 acaacgcatt gaacccatct tgtatcatct gttcgtccgc agagagaacg gacgcagcct
     5761 cgcccgtttc ttttatatct tttgtgtcct ttgtatcgtc catggtttta cacctcccat
     5821 ttttatactg tatagccaca aatatataca aatatttgga aggaaaccct aacaaaagac
     5881 aaaaatagaa tatctactgc ttaaatatgg atcccatagt cgtgtttaac ctcgtccatg
     5941 acaaaagtac ttctcaacga gcccaaacta tcgatcgttc ctaacacatt taaaataaac
     6001 tcttgataat atttcatatt gggagcgtgt atcttcaata agtaatcata atcgcctgaa
     6061 atattatagc actccgttac ctcggggatt tcttgaataa tccgggtaaa ctcaaaagct
     6121 atatccttat tcagccgaac caatttcacg ctacaaaaga caacaaagcc ttgattcagc
     6181 ttctccgcat ctagtaccgc tatatacttc tttatatatc cactattctc aagacgtttt
     6241 aaacgctcga acaccggggt tgacgagaga ctgacccttg ccgccaactc tttcgtagtc
     6301 aaccgggcat tatcttgtaa cgttcggagg atttgcagat ccaccttgtc taacttatct
     6361 gaaacattca taagaaaaaa attctatcgg attgattccc cagcgtcctt cgccgaagat
     6421 gtattctatt tatagcccta aaaatagtat tattttctat attctcaacg aatcttgtcc
     6481 aaaaagcaca cacatcatac atttgccaac agaataagaa ctaaataaac aagatgacta
     6541 tggcaacaaa gaagttacat ttcgagacat tacaacttca tgtaggacaa gaacaaccgg
     6601 atcccgcaac cgacgcacgt gcagtaccca tttatcaaac aacttcctat gtattccata
     6661 acgcacaaca tgcggcagac cgtttcggcc tacgtgacgc agggaatatt tacggacgtt
     6721 tgacaaactc cacgcaaggc gttttcgagg cacgtgtagc tgccttagaa ggaggtgtgg
     6781 caggtttggc cgtggcttca ggagcagcgg ctgtcaccta tgcgttacag aacatagtga
     6841 gggcaggaga tcatattatc gcggccgata atttgtatgg aggttccttc aacctgatca
     6901 cccatacact ggcctcccaa ggcattacta atacgattat caatgtaaat gacctaaacg
     6961 cattagaagc agccatccgg gaaaacacga aagccattta tgtagagaca ttcgggaatc
     7021 ctaactctga cgtaacgaat ctggatgcgg tagcggaagt cgctcaccga taccatgttc
     7081 cattaatcgt agacaatacg ttcggaaccc cctacttgat tcgtccgatc gaacatggag
     7141 ctgacatcgt catccattcc gccacaaagt tcataggggg acacggcagt agcctaggag
     7201 gtgtaattgt agatggaggt actttcgact ggaaggcgaa tgccgataag tttcctacat
     7261 tagccaaacc agacccaagt tatcatggag ccatatttgc ggacgtagca ggttccgccg
     7321 cctttgtcac ccgtatccgt gcggtcattc ttcgcgatac cggggcaaca atctctcctt
     7381 tcaatgcttt tatcttgttg caaggattag agaccttatc cctacgcgtg gaacgccatg
     7441 tagcaaacgc attgaaagtc gtggattatt tatcaaaaca tccgaaagta gaaaaagtga
     7501 atcatccatc acttcctacc catccggacc atgaacttta caataaatat ttcccgaatg
     7561 gtgccggcag tatcttcacc ttcgagatca aaggcgggca ggaagccgct tggaaattca
     7621 tcgactcact ggagatattt tccctactag cgaatgtcgc cgatgtaaag agccttgtca
     7681 ttcatccata cacgaccact cattcccaga tgagcccgga agaacttgcc caacagcaca
     7741 taacaccatc caccgtacgc ttgagcatcg gaaccgaata tatagatgat attatagatg
     7801 atctggatca agctttcgct aaaatctgat agcgcacttc caaaaggaaa aggacagaag
     7861 caaagaaggc gatccctgtt cgacacaagg atcgcctttc taatcaacat cacatcgagc
     7921 caaggttaca ctcatttatt ctcagccaaa tagatatccg taaatgtcac agctccggtt
     7981 aatcggttat tgttgttagt tacatttaac aatatgacat acttgcgata ctgatcggca
     8041 gtcaacgcct ctttcatcag cttcaaattg ccgtacacgg ctttttgcaa tcgttcatcc
     8101 tgacgcttca ggtctttgct caaactcttt ctttgttctt gtacaaaata atcattaatg
     8161 ttaagtacct cctccatttg gtaaggagcc aatcctagat aagaactcaa tcggctaaac
     8221 tctaccgcaa acggttcttt attcccatat tcattcacac attgcgcttt cgcaaaattc
     8281 attgtagcac tcattcccaa aaccgctacc gccataatta actttctcat aatacctaca
     8341 atttacctat tacaaaacca tttacaaaac aaacactcat tttagagaag atagcctaaa
     8401 cattcttttg tttcggacta atcctttttt acaaacctat taacctatct aatgtgtatg
     8461 ataaaactcg gattaacatc aaaatttcaa cttacatttt attgatgtat ctccttgttt
     8521 atattgcaaa gatgaagaat tatcggatag gaagtttccg attgttgacg aaaaggaaaa
     8581 aatggggatt gaacacgaaa agggcaaaaa aataccggct ttaagagaac cggcatttct
     8641 atttaattat tattccagac ttactatcca agacttaaac tcggatgctt tatttttact
     8701 aatatatata cgctcaggca cttctatatc caaagtaacg agcaaacggc tatcaaacca
     8761 aattgttatg tccttcacgc tatcacgaga aatgatgaat tgtttattcg cacgaataaa
     8821 atcagcagga cttaaagaag aaattatctg ttccaatgtt ttagcatatg gatacgaatt
     8881 accactcttt aaataaacat atgtattctt atcagccgta tagaaacaag acacatcttt
     8941 caagctaata ggcaacaatt tatccttaat aggaatcagt agtttatcct tgtatttagg
     9001 agtagtagac aactgtgtta attgggataa ataatggatg atatcttgat gattccatcg
     9061 gctaaactta tctaaggccc ttttcaattc ttccgactta atcggcttca agatatagtc
     9121 tatgctgttt actttgaaag cgtcgatcgc atattgatcg tacgccgtag taaagataat
     9181 cggtgcctcc acctctatct ggtcaaaaat agcgaaagcg gaaccgtccg ataaatgaat
     9241 atccataaaa atcaaatccg gcctcggatt ggcttgcagc caacgtaccg tttgctggac
     9301 actctccgta tttcccatga tctcaagcgt gggatctatt gtaaccaaca tatccgctaa
     9361 gttctcatag gcggcggtct cgtcctctac gatcagtatt ctcatatagc atcattttag
     9421 gggtaggtat acctgaaact catcctcatc agattctacc cgtatttgtt tattcattaa
     9481 tagcaagaaa cgattctcca gattcttaag cccggttcca ttcgtatccg gtaaggtcaa
     9541 tttcggatag attggattag aaacaaccag ttccattcgc tcgttcagcc ggatcaagat
     9601 atccatccgg tgctcgctgt ctataatatt atgtaccgtc acgttctcta ccaacggaag
     9661 caaagataat acgggaattc gcaagttccg cttatcttcg ggaacttcga tcgtaaaagt
     9721 aagcttattg gcgaaacgga ctaccattac atgctgaaaa gcctctataa acgcaagctc
     9781 ctccgacagt ggtaccaaat tctttttatc actctgaagg atataacgga atatatcgga
     9841 caatttcgta acatacaaca aggtattctc atcgtttttc ttccgtatca aggaggagat
     9901 tccattcaat gaattgaaaa agaaatgcgg attgatctgg ttcaccaatg catcgcagcg
     9961 gctctgcaaa ttctcgacac gcagattctc gatcaattga tccttttccc gttgattgtg
    10021 atatagcatt tgtatatagc cgatcaaggt acataacaac gccaacacga taaactggaa
    10081 gataatgata ctcaaaaaac gatcataact aatagtcagg aaggagatca atttatagac
    10141 aacaaagcct ccggaaacgt acagggcatt ccagagcaac cgctcgaaga aggaggtaca
    10201 atcctcatgc ctcaagttac ttttcagcaa aaaccaaata agtccccaga agtaaagaaa
    10261 acggaaccca aagaagagta aaaatccttg atgatcgttc ggagccagat agctcatgtc
    10321 acaaaagatc catgccaaat tcgggtaggc gataaacacc gcgcaaacca aactgaccaa
    10381 ccaaggttta gccttgacca ctgatatctt ttcatccaat gaacccatac gattgtatct
    10441 tttttcgtat acaaaggaat aaaaaatcat tcacatcctt ctccagtgca ggaagaaagc
    10501 gaaaaaaaag agttaaagac gaattatccc cgaatgatca tcctaccggt atcttcagta
    10561 cttgacccgg acggatatcc ggacttgaca gcccattcac cttttgtaag gaagaggcgg
    10621 taaccccagg gtatttcttg gaaatcgaat aaagcgaatc tcccgattta accttataag
    10681 agacaaaatc tttattagcg gaagcgatct gttttgtagc ggcggaagcc gactttttcg
    10741 ttgttgtcgc agtcgatttc gcagtcacgg tagttgattt caccggagtc ttggtagccg
    10801 aggcaaaagc gacaccccca ttatctacat ataatcttaa ccgttttcct ttcgctaccc
    10861 ggttggagcc tagcccgttc catttacgga tatctttcgc tgtcacgcca tagcgattag
    10921 cgatcgtata aagattctca ccactcaata ccacgtgggt gattttttcc cgggtcgcac
    10981 cacttggtaa agagccatta gagttattcg cagaaatgca attcgccaac agttcctcga
    11041 tccgatgcgt atagaccgta tcttctttat cgataaaagc ataggtttcc gccgcaggta
    11101 gtttcaaaac cgaagggcgg gtattacccg gaacgatgtc tcttttatat tgtggattta
    11161 acgcacgcaa cgtctcaata tctacttgca atagatccga tacctgctgc aaatgtaggg
    11221 cattattcac catgaccgta tccgtggcta gcggcaagct ggtttgcatc ggacagatgt
    11281 tatgctcgca ataataattc atgacgtaat tggcggcgat aaataagggg acgtatgaac
    11341 gagtctcttt cggtaaataa gggaagatat cccagaagtc cgtcttgccc cccgaacgac
    11401 ggatcgcttt attcacgttg cccggcccgc agttataaga tgccaacact aaattccaat
    11461 ccccatagat agcgtacata tccttgaaat acttacaagc ggcctcggtc gctttcaagg
    11521 ggtcccggcg ctcgtccacc aagctattaa tctccaagcc atagctctta cccgtaggaa
    11581 gcatgaattg ccataaacca caagcaccca cacgagagag ggctaccgga ttcaaggcac
    11641 tttccacgac ggcgagatat ttcaattcaa taggcaggtc atgctcatcc aacacctgct
    11701 cgattatcgg aaaataaaag tccgccatcc ccagcatata acgcactaaa tttcgtttac
    11761 gctccgcata taagtcaata caatcacgca ctatattatt atagggcaaa gcgatcacgc
    11821 tgggaagcct agacaggcgg tcgatataga ccgaatccgg gaaatagaca ttctcgtcgt
    11881 catcatggca aaagtcctct ctttttgaga aatattgcac atgccaagta cggagcaaac
    11941 tatccacgtt cgcatccaag ctttccggaa tcaatccgac ctcagactcc agcgagctta
    12001 aggtatcttt ttcctcaatt cgggtctctt cctgcgcata gaccaatgag accaaacaat
    12061 ttaaacaaat gagtgctagc aggtatcttt tcatgtatat cagaatttta gactgcaatt
    12121 caatccgtaa gtacgaggcg tgacactcgt cttcggacta acaaccggct ccaaatgcaa
    12181 ggataaatcc ggtgatatat caaaatcgaa taactgggca tccacgtagg catccacgat
    12241 actcaacgca tacaccccga ccgtaataat tatactcaag tctctatatc gacgaaaata
    12301 atccttctgt cttttcaatt gatccttgaa atttgaatta ttaatcgcat cctcaggagc
    12361 catggaagtc aagtcttgcc aacttttact ccaagcatcc ggattttcca gattcttagc
    12421 ggcatcatac atgatatcct tataagccgt cgaataatcc ttatagttct tgttgttcca
    12481 agtcacggca tacatacatc ccatcaagcc accgtaaacg atcggtaatt tccaatattt
    12541 ccggttatag atctgtccca gacccggtac caaggcgaac aagaccgctt ttgtcggatt
    12601 cggcttaaaa gccagcttca tcttcacttc cggtacaccc accgaatcgg ccgccatcaa
    12661 gacggcttgc acggtagaat ccggggcagc tacctccacg gaatcggaaa ctatagcagg
    12721 aacggctttc tccgtcttat cctcctgtgc gttacccatc ccggcatagc acatgaatcc
    12781 gatcaaaagg agtatgattc gatttctcat ttcaatttat ccagtaaccc gatcaattgc
    12841 tccaactctt cttccgtggc gaaaggaatc gtaattttac cttttccctt ctcattgcaa
    12901 gtcaactgga ctttcgtatt gaagtaacgg gacaaatgat ctttcagcaa tttaaactct
    12961 tccggaagta tcggcttacg atccgatttt ttcttttccg gcaattccgg ttgtattccc
    13021 tcggctatat tacgcaccat ctcctccacg ttacgaacgg agagtccttg agccaatatc
    13081 tgctcatata aagctaattg aacctccgga tcatccaccg ggatcaatgc ccgggcatgt
    13141 cccatatcga tcttcttgtc cttcaatcct acttggatct cggcgggaag tttcaataaa
    13201 cgaaggtaat tagcgatcgt agcacgtttc tttccaaccc tttcgctcag cccctcttgg
    13261 gtcaagccgt aattatcgat taatttttga taagctaacg cgatttcgat agagttcaag
    13321 tcctctcgtt ggatattctc tatcaaagcc atctccacca cgttttcgtc ggccgccgtc
    13381 ttaatataag cgggaatacg ctccaaacct gcttttagcg acgcacgata acggcgttcg
    13441 ccagagatga tcatatattg ctcggggccg atttccttca acgtaatcgg ctgtatcacg
    13501 cctaacgagc ggatagaggt agccaactcc tccaaggtct cttcctcaaa gatggatcga
    13561 ggttgttccg gattaggctg gatcttgctt aactcgatct cactaataga cgatgaacca
    13621 cctgtcttca ggtcatccat cgtaattaac gcgtctaatc cacggcctaa cgccgatctt
    13681 tttaatgctg ccataatcct ttattttttt caacaatctc ctgtgccaac tgcatatggt
    13741 tgatagatcc tttcgaatcc gcgtcataca ataagacagg tttaccgtaa ctggaagcct
    13801 cgctcaactt cacgtttcgt tggatcacgg tagtaaatac caaatcacgg aacggacgtt
    13861 tcacttcctc ataaatctgg ttcgccaaac gcaggcggga atcatacata gtcaagagga
    13921 atccctctat ctccagtgcc gggttcagct ttgatttgat aatcttgatc gtgttcaaca
    13981 gcttactgat accttccaag gcgaaatact cgcattgtac cgggatgatc accgaatcgg
    14041 cggctgtcaa ggcattcacg gttatcaatc ccaaagaagg agagcagtcg atcaggataa
    14101 aatcgtactt ctctttcagc ggtgtcaata tctgcttcaa gatccgttca cgattctcca
    14161 agtttagcat ctcgatctcc gctcccacca aatcgatatg agaggggatg atatccagtc
    14221 cttccacttc agtctgtgtg atagcgccgc tcgcatcctc accgttcacc agacattcat
    14281 agatagaaag ttctacatta cgtatgtcca cacccagacc ggatgaggca ttcgcctgcg
    14341 gatcagcgtc tacgaccagc acctttttct caagagcggc caatgacgca gccagattaa
    14401 tcgtggtggt tgtcttcccg actccacctt tctgatttgc taaagcgata atctttccca
    14461 tactatacct aattaattcg agggcaaaac taaacattaa aaactgaacc aaacagggtt
    14521 caatcaaaac aatgcttgtt ttgttgataa atcgccctaa ctgttgataa ctcgcaaata
    14581 taagcagaat aaatcaaata gagggttata aggctggtat ataggtgttt ttttggaaat
    14641 gataacgaag ttttaaacaa gccaagcttc cccttttgag gatctccgca attaccattt
    14701 tgacaatttg taatatcaac tcccggagaa tcgatttttc cggacttatg gacaactcac
    14761 tctctaatac gagaaaaaat ttcagcaatc atttacgtga cagactctta tcgaaaaaca
    14821 gcctttcatt ctagcgaaat ttatccattg taattcatat ttaaggggtt gattaaggga
    14881 ctttatggga ttagaactgg gtcataacag gggtatgatg cccattcaca agtatcaaca
    14941 accctattct tgactgctca cgatgcccaa cggcattgcc ggagttgccc aatgcgacct
    15001 atcgcataag ctttcaccat ctatcgcata caaaaagggg gcttttctaa taaaaaatac
    15061 cgtttacagt catccagcct ctgctatttt atactctcca ccagaaagga atgtcataca
    15121 tatagacata tatcaatcaa aaagaaagaa taacgtttgt ttcatcgaca gaaatactcg
    15181 taacacaaca cacaaaagcc ccgccgaaat acatcgacgg ggctctacct tatgaactgt
    15241 gtctttcctt acggaaattc gatcagtttt ctacttattt aacgatcgtc ttaacagcct
    15301 cttcaccctc aacagctaca gctacgatac cagcaggtac agcgatagtt gcgttgtctg
    15361 aagtaagaac tgtctcagca acaaccttac ctaagatgtt agtgataact acagacttac
    15421 cagcagcgcc ttgaacagtt acagtaccgt tacctgctac tacggatacg ccttcagtag
    15481 cgatttcgtc attagaagtt accatatctt cttcttcagt cttctggaat gcgttgaata
    15541 ccaatgcacc gtcgccacca gtcttagcgt tgtcgaatgt agcattcaca tctgtcaata
    15601 ccaagcaacc attgtgcatc ttcaaccaag cggcagcagc cttcggagcg atagcctgag
    15661 ttgcatcacc atttacagtt tggtattgag tatcatgagc tttatcatat acattagact
    15721 caatcaagaa tgagttattc tcgccttctt ttccatctac ataagagata gcagctaaat
    15781 caggatttac ataacggaat gaccaagtta cattcttatg tttgtcacct ctcaaatcat
    15841 tgatgaatga aggatattct ttcttataag tagcgatcat agattcgata ccctcgttct
    15901 tcaattgctc tttcgtcatg tttgcatact tgccagtcaa gactaacaat gtatcaccat
    15961 attgaacagc aggaacaaaa cctacgcgag tatagctact gttagaaaca gctttcgtat
    16021 tgaagataaa cggatttacg tcagctttgc aagcaactgc agaatcagag aagttaacta
    16081 agtacttacc ataaacgaat gccggagtct taacatgaac agcgtgtaca cattcgtaag
    16141 gattctctgt cggagttcca tcaggtttga tgtgcttacc atcctctgta caaggaatga
    16201 tcttctcacc tgcgattaca tcttggaatg cagaaatcaa gtattgaggt ttgatctcgc
    16261 ctgcgccacg tttcaaccat gcagtatcaa cacggaatgc caatttacca ttagctttat
    16321 ccttgttcca aataccagcg tagtccactg tagaatgttg caggttcgtg ttgttctcat
    16381 ccattaagta ctccttacgg atagactcta cgaaatacaa gctatcagca gcatcattag
    16441 cattctctcc aacaagagta ttgttgaaac gacgatacaa cggagtgtta tcaggagcga
    16501 tatagaacgc agatgttctt gtttctttca aagtctgagc cttcaaagaa gcagatgcgt
    16561 catagtcaga tacaccagct ttatagttac ggataacgcc atccacgtca gcctctacaa
    16621 ttgcatagta atgagcaaca gtagcacctt cttcacgagc gatacagttg ttttctttga
    16681 agtaaacaga gtctgtagtt tgatgcaatt tacttactgt atacttattc tctttagcct
    16741 ctgcgtagct accaaagata gcaccatcgt aagaaacttg atacatagtt cttaccaatt
    16801 gagctaatcc cgggattcta cccttttcgc catttactaa agaagcgtca taaccatact
    16861 tatgctcttt acctgtagtc ttgatagtaa acggagtctt gccatctttt acagtcatcg
    16921 tagaatcttt cataactgcg atatatttat cagcagcata cggatgccaa tagttgaacg
    16981 tatacttatt aaccatcaac tcatccttag tcaaattctt ataaccaaga tacttatcag
    17041 aatagaactt cttatctact gcgatcaact ctagagaatc accagcaagc actgttcctg
    17101 cgttagtagt aatatagaaa tacttaccac ctacattctt gttcaactga acagaactca
    17161 atgttactgt attatactca cggttccaag catcgatcgg agaaatatta tttttatcaa
    17221 cagcattctt tttcaaaaca acccattgat aagcaggcat atgattagca tcttgtaagt
    17281 ccaaagacgc ccattctgct gtgtttgctt tctctacgtt gttgacccaa gttgtatcgt
    17341 tatgcaaagg tattgccaaa tacttaccag tcttagcgct cttaattaaa taaacgccat
    17401 cagcaacaga agtctttgta gaagcaaccg gattacaatc catattgccg aaagagatat
    17461 gtgtattttg ctccttagca tcaaccgtca agattcgagt ttggttcttg atcaagtctt
    17521 gcaaagaaac acgccagtta tcacctgtcg cctctggttt ttttacaagt gtctcccaat
    17581 tagcttttgt ctcattccaa gtgattgaat gcacatagat atataagcta tcataagccg
    17641 gagaataaag gaaagcaaat ttatgttgat cttgaatttt actgcctctc actgcatcta
    17701 tagcttcgcc tgttttacct ttcttcgtcc aattgtaagc caagaacttt gtaccgcttt
    17761 catttgtata agctgtatca actcttaaat aagcttcttt cttcaaatca gaaatataca
    17821 aatatttagt atcaccagat tcttctgcta agaatttgtt agcgttaaac ggattcgtca
    17881 aagttgtacc aagcacatcc ttattaaatg tcaatttaac accagcatcc tccttttgca
    17941 caccgaagat tgtattcaac tcctcggcac tcaaataaat ctgacccgga gcttgtaatg
    18001 taaacttcgc aaagccagct gtctcagctt tcttagctcc ctctttctgc acataaactt
    18061 tgtcatcgtt agttttcact gaaaaaccaa caatagaatc ggcagagaaa tgagagaaca
    18121 gaggtctctc cggttccaac ttattgattt ctctagagaa agcccaacca gaaatttcac
    18181 ctccagttgt agggataacg ggtgtacttt cttcagcacc tacgatatca gacatagtta
    18241 tatccaacat catacctgtt cccttattca tgaaatcata cttgtgagtc tgaccttgat
    18301 tctctgaagt aacagttaca caccataaag tgttagccaa ctgtgaagag gtagtaacgt
    18361 ttaccaaagt caacttacca tccttatcca ttgataagac tttgtcagaa tccttaattc
    18421 tcaattggaa taaaccagtg tttgttcctt ctgctaactt aacgatagga taagcactag
    18481 cctctgttgg caaactgtta tcctgcaccc cctgtgcata aacagaatta actgatacag
    18541 cactcaaaaa tgcagcacca gccaaaagcg tagaaaactt tttgttcata attaaataat
    18601 ttaatattaa tactaaagtg taataagctc ttctattgga ttgcctgcct tttaaacgga
    18661 cttagggcaa tcggttttat tcatcattgc aaaggtacgc gtttctttga ttcgtgcaaa
    18721 tcttccctat tatttttttg ttaccatata cgctttctta tcaatcaaat aggctattca
    18781 ttacgaaacc gccaattata aagacaaacc atctcttatc caataccaca atacttatct
    18841 tcggttcatt cctccaacag atatacacta ttacacacat tttataatgt acgtgtacat
    18901 tataaaaata cgtagtaaaa aatcactccg atcaaaaagt catttgcaat aagagacttc
    18961 cttaaaagca taacggcgaa tgcttccatc ccgtaatgct agcaaaagat gcccggttga
    19021 ttctatatca tggatacagg cctcgaactc gccggactca tccttataac catgataccc
    19081 ctctcttcta tacaaagcgg attgataacg agctcgaata tcctcgtgtt cctcttggag
    19141 aagagataaa taatagcgat agaatattga gaggaaacgg tgcaaaacct cttcccgatc
    19201 tacttcctta ccgattattt gaaacaaaga tacaggattc ggagcatctc ctcgaaatac
    19261 cgtttgattc aagtttatgc cgatcccgat gatggagcaa tacagattat gccccgacag
    19321 gtcgttctca atcaacattc cgcaaatctt cttgtctttc cagtaaatat cgttcggcca
    19381 cttcacggtg atatgatccg catataagtc caacgcctcc ttcacgctta gagctgctat
    19441 ttgagaaatc aagaactgac ggttcgcagg gatgcacgta gggtacagga ctaagctaaa
    19501 catcaagttc tttcccgcct cagactccca agtattcccg atctgaccac gtccggctgt
    19561 ctggaaatcg gcaacgacca cacttccttc cgcaagagat tccttgatga ccaactcacg
    19621 aagcaagcta ttcgtagaag cggtttccgc cacacgcaag atgcggggag attcattatc
    19681 agtgctcatc attataaatt tcccttatat tttttggtag tttagcgatc acttcccggt
    19741 aagaatggaa gatccagcgt ttaatctcct cgtcttccat atcccggtcc agataaatgc
    19801 tattccagta tttcttatta aaatggtaag ctggctcaac cgccgtataa tgttcccgta
    19861 actcttccac ataatccgta ctacatttca aggagacatg aggctcctcc gcatccaaag
    19921 gaagcagcag gaacatctta ttctctacct taaagaccag cgatacctca tcgaacggga
    19981 aacactcgat ggtattcttc aaggaaaggc agtattcacg tacttcttct atattcataa
    20041 cttttatctt ttaacggcaa ggagcataga aagcatcttc gatatggtcg atcaggaaac
    20101 ccgtctcttt cttgatcaat gtcacgatat caaaacggac tggtaagtct atattaaaat
    20161 aacggacata ggcatccgca gcggcgacaa tcctccgaat cttcttggtg tctaccgcat
    20221 cttccggtga aagcaaaaaa tcctcagagc gtgtctttac ctccaccacg attaactcat
    20281 cttccttgac agcgataata tccagttcat aatgatgcca atgccaattg gtatgcaaca
    20341 cgttatatcc atgttttacc agataggcac gagcctcaga ctcaccttcc cgacccatat
    20401 cgttctgtct tgccatcgca ttaatttgca caaatatagc cattttcttt gttattcggc
    20461 tattcactcg tacatttgca aatgtatgaa agaagaacgt aaatattcat cggctcaccc
    20521 caatcatccg agggtacaca aagtgacctt tatgctgaat gacgaagagc ataaagcggt
    20581 aaaacgttac ctttcacgct acaagatcga gaataagtcc cgttggtacc gagagacgat
    20641 cctttctcac atcctcaaga ccttggagga ggattatccg actcttttca acgaaaatga
    20701 gatgagaaga tgaatccttt caatgacgaa tatttcatga agcaagcgtt ggtggaagct
    20761 cgtgcggcag cgtccgaggg tgaggttccc gtaggagctg ttatcgtctg caacaaccag
    20821 atcatagcga gggcgcataa tcaaaccgaa tgcttgaacg acgtgaccgc acatgccgag
    20881 atgttggcga ttacggccgc cgccggagtc ttaggagcga aatacctgac aaattgtagt
    20941 ctatacgtaa ccgtggaacc ctgcataatg tgtgccggcg cgatcggatg ggcacaatta
    21001 agcacgatcg tatacggggc atccgatgat aaaagaggtt tctccaaatt cgcccctcaa
    21061 gccttccatc cgaaagcgat tatcaaaaaa ggtatccttg aaaaagagtg cgcggaagaa
    21121 atgcagcgtt tctttaagca aagacgctaa gctctattta acttcctcgt aatccacata
    21181 ctccccttca tccttggcga atatcttctt acggtgcaca taaggtgtac gatcatcatc
    21241 atcgtcccgg gcggtagtag tcgtagaacg atgtccggaa gtattgctat ttgtttgacg
    21301 acgttgttct cccttacgag tgctgtttcc gctaccaaaa aagatgttct taaaggtacg
    21361 caagatggag aaacccatca gaaacaccaa caggataaag aaaaagaata ttacaaacaa
    21421 aaacttaaac ataatccgat acttaaatga ttctttacta tcacaaacac aaagataaga
    21481 attcttgttt atcccttttt gttaaaaata gacaagacta tatataacag gatggttcca
    21541 gagattccca agaatcccca taacgccacg aaaataatgg cacaagcgat caatatatag
    21601 cgaagctcat tacccttcca cgctaaggat ttcaccttca gcgagaacat cggtatctca
    21661 gacaccaaca gcaaggaggt aataaacgcc aagataacag tcaccaacac gaacaagcct
    21721 tcattcgcat ggataaccgg taaaacagaa tatcccaccg aagcccaaaa taaagcatgc
    21781 gccggaaccg gcaagccgat aaacgaggta gtttgccgtt catcaatatt gaacttagcc
    21841 aaacgcaaac ctgaaaacgt agggatcacg aacgccagat aagggatata cgtattcaaa
    21901 gagccaaaag gcaaagccgt agaagcctct cccaacaacc aatagaccac catgcccgga
    21961 gcgaagccga aacttaccat atccgacaag gaatccaatt cctttcccat cggcgagtaa
    22021 gccttcaata aacgagcggc aaagccatcg cagaaatcaa agaccgcggc tataataatc
    22081 caaatcaacg cagataaaag atttccgtgc aaggccataa cactggcgac acaaccggac
    22141 agaaggctta gacacgtaat tgtattagga atatgttttc ttatactcat tttgacaaac
    22201 gggctatagg cgtttgattg cctgttactt tttgatccat ctctattaac acctctgttc
    22261 ctaccggcag gtagacatcc acgcgagaac cgaatttaat aaaccccatt tgctcgtcca
    22321 catgacattt ctctcccggc ttggcatacg taacgatgcg gcgtgccatc gccccggcaa
    22381 tctgacgagc caagacatcc accccgttcc tcgtggtaat cacgaccgcc gaacgttcgt
    22441 tctccgtact actcttcggc agataagccg ccataaaacg cccgttctgg tgggaaacat
    22501 gcttaacggt accgtttacg ggaaaccaat tagcatgcac gttgaagata gacataaaga
    22561 tagatatctg taggcacttc ttatgaagga tctcgttctc catcacttcc tcgatggcaa
    22621 cgatcgtacc gtcggcggga gcgatcacca agccttccga atcataagga aaccggcgga
    22681 aaggactacg gaagaagttt aataccaata ggaacaatac ggtagaaaca aaagcgacag
    22741 aataaaacag cataccctta cctaccgtat ggtacaaagt tatattcaca ataaataata
    22801 ttgtaaacaa cgtaagcagt aaaccggttc cttctttatg tactttcatt cttctttgac
    22861 tgtatcgttt tatactaaga atctgcaaaa atattcattt ttaccgaata tcaaaaatat
    22921 atcacttatt cactgcctct attttaccta actctacgta ccaaaggtat ccatcgaccc
    22981 gctcgaaacc cattttacgg attaattgca ggtaatttct tacctgatta ggatggcgct
    23041 tatcttgccg ttcgccaaat ttataatcca cgacaataac cttacctcct tttattatca
    23101 cccggtccgg gcgtttagac aagcctttac cgaacaggat atccacttca ttcaagacac
    23161 gggcggaacc atcataccaa gcctttacct cctccgcttg caataattct tccagacggc
    23221 tgatcaactc cgccgcttcc tcccggttaa tcaccccggc taaccgataa ctttcgaccg
    23281 aagcgggaat atctttcggc gtacgtatcc ggctcaatac ctcatgcatc aaggtaccgt
    23341 gcttccgcct ggcattatcg aaaaagaatc ctttcccatg caggcgtaat tgtaaacgat
    23401 catccgggga aacggaatac aggcggctca tggggatttc ctccagggta tcttctgccg
    23461 ttctacccga agctggatgc caccattcgc ccctttcaaa ggtatcatcc tcgatatccg
    23521 tctccacccc cgcccacaat agatcggcga tggaagttat cttctcaacc ttaccttcct
    23581 tgttgatctt cctcggacgg ggggagaata cgatcagttc ttctttcgaa cgggtaaaag
    23641 cgacgtataa ggtgttcaag ttatcgatga aagcatgcaa gcgctccttg aaataatcct
    23701 tggcgaaaat cgtgctactc aggatctgtc cgtaacggac aggaactaag tgcaggcggt
    23761 caaacggctt cttctccggg tggcaccaaa ggataacggg ctttgtcggc ttatggtcga
    23821 tctcccagtc cccgaaagga atgataacga ccttaaaacc taagcccttg gatttatgta
    23881 cggtcaagat gcggatagcg ttttgcccat ccggggtagc gatcgtcttt cgataaccgg
    23941 tctcgtccca ccatctcaag aaacggttca aatccgcgct ttctttttgg gcgtactcgg
    24001 aaaccatatc caaaaaggct tgcacgaata cctgttccgt ttccgggaag taagcggaga
    24061 agttacggaa gagcccttcg gttacctcgt acaaggattg ccgggagata gactgaaggt
    24121 tttgaaaaac agactcgtcc gcctcgctct ccccaaattt tccggttaat acttgatagg
    24181 catacatcgc caatttcctg ttcgtccggt cctccggatt tcgcaaatag cgcaatacgg
    24241 cgatcaggaa acggaccgcc ggagaactac ccacgaacag ggcatcatcg gagatgatat
    24301 cgtaattgta tcggtcggac ggatgctctt ccttataggc aagcaacgta tcagccacta
    24361 aagcaccttc ttgattggta cgcacgagta tggcgatatc ttttagcgcg taaccgctat
    24421 cctgcaagcg ctccaaggta gcgggcaatc gctccatcgc ctcctgtttc cagtccttat
    24481 cctcatcacc ggagaggaaa tcgatccgta catgtccatc cttcttctgg aagggcgggg
    24541 ggacacgctg ggaactatcg tcgtaggccg ccatgatcct cgcagaaaag gccgtgcgct
    24601 cttcctcgct taatgaggag tttttcaacg cctcattata tagatcctgc aggatcgccg
    24661 gagcggcggt gaagaacgca ttattaaact ccacgatatg gcggcagctt cgccaattat
    24721 cctttagggt atcctcacgg acttgctcgt cctcgaaatc cctgcggact tgctcgtcca
    24781 atagcttcca atccgagtta cggaaacgat aaatactttg tttcacgtcg ccaacgatca
    24841 gattcgcccg gccattcgcc agactctcct ccaccaaggg gcggaagtta ttccactgca
    24901 tgccgctggt atcttggaac tcatcgatca tataatgatc tacgtgcgta cccgtcttct
    24961 cgtagataaa gggggcgtca ctgccgctga tgaccttatt cagcaactcg gtcgtatcgg
    25021 cgatcagcat gacattcttt tcttcccggt aaaaggcgat ttgccgggag atatcggtta
    25081 agatccctaa cgtataataa taacgtacga tctcccgggc cgtgttatag gccgtcaggt
    25141 tggcgaacag ggatacgata ttctttacgc aggcattcaa cccttcctca tatacacacc
    25201 cgatgatctg ccggagaccc ggtggagtcg tcttggtcgt ataggcatcc ggattatccg
    25261 gcaaagcttg gaacgtggct gtcggctctt tcatctcacc tttcgccagc ttctcgaaat
    25321 agaaaaacgg ggaacgactt cctcccttaa aatccgaggg ttgtaaggcg aactgtttca
    25381 gcaacgccac tccctcctca cctaaacgtt tcgcctccgc ctctacggag cggataatgg
    25441 cgtatagctc attcttatag gcatcgagcg cctgcttatc cgcgatatcc ttacctactt
    25501 cctcgctaaa tgccttataa ctctccttaa agacctcccg gctgagcgac atgatgtctt
    25561 gccgcaaact ccagccgcct ccatcctcga tcttgttctc ggcgaaacgc agcagccaac
    25621 ctagcaaatc tttgctctcc ggcttctcca gatcggccag caggttatcg atcgcctcgg
    25681 tcaagaccag ttcttggtcc atctcgatgc cataaccgcc ttgcaagccg atctcgcggg
    25741 taaaggcacg catcgtttgc tggaaaaagc ggtcgatcgt actgatatta aaagcggagt
    25801 aatcgtgcag gatagcgacc agaatcttcc gggcctgctc cctcacctgc cgctccgtca
    25861 aggaataggc ggaagagagt agctggatat aatcggacgc acggccggaa gcgaggtgat
    25921 aaagttcttg aacgatacgg gttttcatct catccgtcgc cttattcgta aacgtcacgg
    25981 ccaagatccg gcgataagcg cccggctggg agaagagcaa catcaggtac tcccctgtca
    26041 gcttatgcgt cttgcccgcc ccggcggaag ccctatagat tgttagcata gcgatcgggg
    26101 attagatcgt acggcttttc gaatagccct ctttccggag gatatccaac accttggcac
    26161 gcaggtcacc ttggatgatt atctccccgt ccttagcgga accgcctacg ccgcatttca
    26221 ctttcaagag tttccccaag gcggtcagat cctcggaagt gccccggaac ccggtgatca
    26281 aggtaaccat cttccctccc cggttccgct tatccaagga tatgcgcaaa gcttgtttct
    26341 ccttcggcaa cgtatcttcc tcttccgtat ctcccgtatt atattgaaaa tcgggattcg
    26401 tggagtacat cacgcctaat cgatctttcc aatcattatt cttcataaaa ataccacttt
    26461 attggctcaa agctacgtat taatctccga ataggcaaac aagggcgaaa aggctatcct
    26521 atcaagatgg aactattacc attttactac atataaaacc tttattttca ggcaaacctc
    26581 ttgcttaata aagcggaatc actacatttg ctaccagaat cacgtttgct acatatatcg
    26641 cttagaatta acggccatga gaaatatcat tctttttatt tttattatac taacggtcca
    26701 cttgaacatg agcgcacgag gctccggcga gaaaccgtct atagtcgtac tgcactccat
    26761 caacttcgag gaaagctgga caaaacagac ctatcttgat atagaaagaa aattcgggga
    26821 ggaagggttt accgtaaagg cgattccctt acagatcccc ggtatccgca cgatggaagg
    26881 gtttcaagag aagagaacaa tgatcctaga gagagttccc gtgccaccca ccttagtcgt
    26941 atgcatagga gatccctctt ggcttgtcgc ccgcccgttg tttgacaagg aatggaaaga
    27001 tattccctct atcatctgct acgccagaga ttatatgtac ccgaaagaag agtacctgat
    27061 agacctagat aaaaacgtgc tcgatacgct ggttcccatc acggacgtag taaaagacta
    27121 taacgccact tttataaaat acccagtcta tatcaagcaa acgatcgagc taatcaaaaa
    27181 gctacaaccg gaattaacca aactggcctt tatttttgac cgccgttata taagccagca
    27241 aacgaaagcg gatgtagagg ccgtgctacg gaaagatttt ccgggcatcc aattcgagcc
    27301 actgtctacc acctccattt ccaccgagaa cttattggac agactggcct ctttcgacaa
    27361 taagaccgga gtcctttatt actcatggta caggacccgg aaggataacg agaatcgtta
    27421 cctagtcgat aacgtccaga aaatgaccaa tagtttctcc gtccccccaa tctttacctt
    27481 gcaagacgta caaacagaaa acgggaattt cgccggggga tattatgttt ctccggagga
    27541 ttatgcgcag gtgacggtca acacgatcga aatgatcctc tcggggaaag atagtaagga
    27601 aatcccgatc cagactgcgg aaaccccgag ggcctaccta aattaccagc atctattgct
    27661 tcaccagatc gatcccggcc tatatccccc gaacgccacg tatttccaag agcctcccgg
    27721 tttcttacag aaatacaaga tccatatcat aagcctactc gtcattctgg cgttattgat
    27781 aacgatcggg atcttacggg tccgcctctt catccaaaag caaaaggcca aagacaagga
    27841 gctgcaaatc gcacgccaag cgcaagacct gaaccagaaa taccagctcg tcttgaaagc
    27901 cagcaacatg atgacatgga tatgggacgt aaaagaagca cggctcgaat gtaacaatat
    27961 ttacctgacc caaagatcca ttcgcgacaa gggaaccgac ggccaattct gcatgtcggc
    28021 ggacgagttt tatagcggca ttcaccccga ggacttggaa cagatgcaag acgcgatcaa
    28081 taaactaatc gccggcgaga gcatatcgat cgacgaggag atccgttatt tagacgatac
    28141 agggcttgaa tatacatgga tagagatctt tgcgatcgta gggaaaaccg atccggaagg
    28201 aaaacccgcc tacttaaccg gaggtactac cctcatcaac caacggaaaa aaatggaaca
    28261 agaactgagg gacaaggaga agatagagga atccaaccgg ttgaaatccg ccttcctagc
    28321 gaacatgagc cacgagatac gtaccccgct gaacgctatc gtaggctttt ccaacctgct
    28381 agcggaaact tgccactccg aggagacgag agagttctgc gagatcatcg agacgaacaa
    28441 cgagcttctc cttcaactcg tgaacgatat cctggaccta tcgaagatcg aggccgggca
    28501 aatggatttc atctattccg agttcaacgt atccacgcta ttccggagct tataccagac
    28561 cttccaaagc cgggtgaaag acggtgtcac tctctattgc gagatacctg aacaggattg
    28621 cgttatctat tccgagaaga atcgcttgac ccaagtgatc accaacttcc tcacgaacgc
    28681 ctgtaagttc acgttccaag ggtctatccg catgggatac aaggagaggg aagatggatt
    28741 atacttttac gtaaaagata ccggaaaagg tattgagcgg aagaacctcc cgcacgtatt
    28801 cgagcgtttc gccaaattcg attcctttat ccaaggaacc ggactcggac tatccatttg
    28861 ccaaacgatc ctagagaatc ttcacgggaa gatcggcgta gagtcggaag aaggaaaagg
    28921 gagtactttc tggtttacga tcccatgcgc tgtatcaaga ccgtagcgta agccgagatc
    28981 ccttcctgcc gtccggtgaa gcccagcttc tccgtggtcg tagccttgat agagatatcc
    29041 tcctcgtcca cgttcatgac ctcggccagc gttttcttca tcagagggat atggggattc
    29101 aatttagggc gctcggcggc tacggtggca tcgatattac ccaactcata gcccgcctct
    29161 cttaaaagcc tcatggtatc ccggagcaag atcttactat cgatattctt atattcacca
    29221 gccgtatccg ggaaatgata accgatatcc cgcatattgg ccgctcccag taaagcgtca
    29281 cagatcgcat ggatcagcac gtccgcatcg ctatgtccca ataggcccaa cgtatgctcg
    29341 atcttaatcc cgcctagcca taattcccgg tccggcacca aggcgtggac gtcataacca
    29401 aaacctacac gtatcttcat acccatttat ctgaaaaggt tcttgattcc atccatatcg
    29461 aacgacaagg agaagcgcaa tgtctggtcc aacgggttac tctgtaccgt actgatcaga
    29521 taagcggcat ccaactggaa aacactcatg cggaaaccag caccgactga gaagtactga
    29581 cggtttccct gatatttatt ctcatagtaa taaccgccac gaacaaagaa ctgctgattg
    29641 taattatact ccagaccgat agaggccata atctcctcta gctcgccctt gaagccattc
    29701 ggcgagtcac cgaatgattt gaagataccc gtgatcgggg acatattgtt atattcatca
    29761 tgtttttcct tataagcagc ctcatcctcg ggagtcgtac cttcttgaat aggttcggta
    29821 ggaactaaat atttactcaa atccacatag ataccgattt ggttataatc atcgatcgga
    29881 tacagtaaac cagttccaac ctttaacatc gtaggcaaga attggttggt atttccaccg
    29941 tcgtaagaga ccttcgtacc gatattggag acattaaaac caaagctcca caggcactcg
    30001 ctattcccta agatcacgta tttctccaga taaccggcga tatcagcggc aaaagcgtta
    30061 tccggaacca tatccgcgtc cgacgaggca cccatgtccg aacgaatata gcgcaaggcg
    30121 accgccatag agaacacatc cgataattta cggctataac ttacatcaaa agccatctca
    30181 taaggattca atatgagctg attacccatt cctccatccc ggctttcctg tacttctcct
    30241 aaagagaaat aacgcaagga agctccgatc gcctgcatat cgctatcgcc taatttataa
    30301 taaccggcca gatatgctaa agccacatca ttcaccaatt tacgtaacca aggcgtatag
    30361 gataaagcga ctccggcctt actatagcta aaagcatact tagccgggtt ccagtattgg
    30421 gaattcacat ccggcgtagt agccacaccg ttatcaccca tagcacctcc gcgagcatcg
    30481 ggcgcaatag acaaagacgg tatcgccgta ttaatcgggg cgaatttatg tttaacatcg
    30541 tctgcgcctc cttgggcata taaagccgta aatgccgtca aaaagctgaa aaccgctagt
    30601 aacagactga atcttgaaac tcttaccata tattctattc taaaaataca tttacattta
    30661 tcattcctag agggtaataa acataccccc atgcttatta taaactaatt acccgatact
    30721 ttattgtgcg agaatgatta atttattcgc tttcgtcgcc tctttcgagt tattcgtgct
    30781 aatcgccgcc cgatacagat aaactcccgg gcgcaaccgc ctgccaccat tatccgtcaa
    30841 gttccaagtt acgatataag ccttaaacaa ctcggaggaa ccgctcttct cggtactcca
    30901 taggaactta ccggtcatat cataaaccat aaccgtcact tttaagttcg actccggacg
    30961 attgtgatgc agaaagaatt ccacttgatc ccgtgccgga ttcggggtgg catacatctc
    31021 gatcagatta ggtttcaacc cttccgccac ctcaaaagta aaggtatagg tcgtggagtt
    31081 atttaagata tcccacacct taaactc
//
LOCUS       DBMDTB010000039        30877 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_560_length_30877_cov_11.970042, whole genome shotgun sequence.
ACCESSION   DBMDTB010000039 DBMDTB010000000
VERSION     DBMDTB010000039.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 30877)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 30877)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30877
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_560_length_30877_cov_11.970042"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..536)
                     /locus_tag="ACZPB4_08095"
     CDS             complement(<1..536)
                     /locus_tag="ACZPB4_08095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HIR1098218.1"
                     /translation="MTTELHPLGFFLPENTRLLMLGSFPPPKARWSMDFYYPNIQNDM
                     WRILGLIFYGNKDAFLRDKKAFSEEKAKAFCREKGIGIGDTAMEVIRLKANASDKFLE
                     VVRPIDPEKVLSQIPECVAIVVTGQKAMDTLLSVLPGTEEPKVGFSSEFSCMGRTMRL
                     FRMPSSSRAYPRPLEEKAA"
     gene            complement(533..1174)
                     /locus_tag="ACZPB4_08100"
     CDS             complement(533..1174)
                     /locus_tag="ACZPB4_08100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098219.1"
                     /translation="MNFISKLFKKNVSEAEEAGKGSVEEFVSLIRVYYQAVMAVNLGI
                     TNLNMLADMALFKRMLKIPTQNNKLGVAEKSRVRKVLMEDYGLSEAFFKEIDSSVKKN
                     CKNQNDIKTYFFMFQGFCNDLFNLLGNLMQWKFRFSMLVKKLLYNMTTKTVHDILTKS
                     EWKDISVQKAAWSVRKYAEKLGYSEQWITDFVYNVVLLAKEDQKKELKKNKEA"
     gene            complement(1238..1900)
                     /locus_tag="ACZPB4_08105"
     CDS             complement(1238..1900)
                     /locus_tag="ACZPB4_08105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HIR1098220.1"
                     /translation="MMWDFILRLFVAGILGAVVGLDREYRAKEAGYRTHFLVSLGSAL
                     IMVVSQYGFQDVILENSVSLDPSRVAAQVVSGIGFIGAGTIIIQKQFVRGLTTAAGIW
                     ATAGIGLAVGSGMYGLGIAATLLTLAGLELLSVIFKSIGMRSSLVVFSTSDKEAINRI
                     ARVIYEKGFLLVSYDMKRLGHQEKDEYVVSIVLKARKNTEESPLLLLMEQFPEVTVER
                     IE"
     gene            complement(1944..2774)
                     /gene="murQ"
                     /locus_tag="ACZPB4_08110"
     CDS             complement(1944..2774)
                     /gene="murQ"
                     /locus_tag="ACZPB4_08110"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016835 - carbon-oxygen lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009254 - peptidoglycan turnover [Evidence
                     IEA];
                     GO_process: GO:0046348 - amino sugar catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HIR1098221.1"
                     /translation="MVFQKITESESLYDNLDQMSVRELLEGINNEDRKVAIAVGREIP
                     KIEKLVTRIVERMRRGGRLFYIGAGTSGRLGVLDASEIPPTYGMPNTLVIGLIAGGDR
                     ALRNPVESAEDDLDKAWEELQQYHINTNDTLVGIAASGTTPYVIGALRKARSEGILTA
                     SISCNPDSPMAAEAEIAIEPVVGPEFVTGSTRMKSGTAQKMVLNMITTSTMIKLGRVK
                     GNRMVNMQLTNQKLVDRGTRMIMEELRLDYEQSKNLLLLHGSVREAIDSYHREWRLNQ
                     "
     gene            complement(2778..3632)
                     /locus_tag="ACZPB4_08115"
     CDS             complement(2778..3632)
                     /locus_tag="ACZPB4_08115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HIR1098222.1"
                     /translation="MILIADSGSTKTEWCLADQGRPVRTVVTAGINPFFQTREEIAGE
                     IRDALLPALKGERIDAIYFYGAGCAFPEKNRIVEEAITPYIPAPIEVYSDLMAAARAL
                     CGSRPGIACILGTGSNSCLYDGTEITEHISPLGFILGDEGSGAVLGKLLVGDCLKRQL
                     PAPLVRKFMDQYELTPALLLERVYKQPFPNRFLATLSRFLLENITEQPIYNLVYTSFR
                     SFFLRNVALYPGADTYPIHFVGSIAYYYQEVLKAAALSLGLKVGTVVQAPMDGLIRYH
                     FTNEEKNE"
     gene            complement(3640..5067)
                     /gene="nhaD"
                     /locus_tag="ACZPB4_08120"
     CDS             complement(3640..5067)
                     /gene="nhaD"
                     /locus_tag="ACZPB4_08120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter NhaD"
                     /protein_id="HIR1098223.1"
                     /translation="MLTAMVIVFLVGYLMIALEHPLKINKAGTALLIGTVLWVMYTYA
                     APFFIPRASAEEFSLFLESFPSLGSLTFKEQCTRFVVEHQVLDSIGEIAETLIFLIGA
                     MITVELIDAHGGFMFITNHITTKKKKKLLALIAVITFFMSAVLDNLTTSIVMIMLIRK
                     LLGNYKERWVFGSIIIIAANSGGAWSPIGDVTTIMLWVRGNISTSSTIPHLILPSIVS
                     ALIPVLIAMRFLHGNVTPPNAFSQMEADNELLKKLKDKEKLSILIIGVLCLLFVPVFK
                     TVTHLPPFMGILMGVGILWFYTEMLYARKPIDEDLKLRLSKVVHRIDGATLLFFLGIL
                     LAVDALRCSGVLSDFAFWLDDTVGNVYAVNLIIGALSSIVDNVPLVAGAIGMYPVATD
                     AMVAAATDPAYLANFMQDGVFWQFLAYCAGVGGSMLIIGSAAGVVVMGLERINFIWYL
                     KNISLLALAGYLSGAVVYILQNLIL"
     gene            complement(5236..5760)
                     /locus_tag="ACZPB4_08125"
     CDS             complement(5236..5760)
                     /locus_tag="ACZPB4_08125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011107788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin/lipoyl-containing protein"
                     /protein_id="HIR1098224.1"
                     /translation="MSKALATYFATVNDIPDTEFKVEILEDGPIKKVSVNGTVYDVDY
                     NLGGDTIHSIIMNHKSHGVQISSVGDSTYEVKNKGDYFQVQVIDELKKLRLSRTSSKT
                     VGRQVIQAQMPGVIQKVYVKVGDEVKAGDPLCVLVAMKMENEIRTPIDGVVKEVYVNE
                     TDKVSVGDKMLVVE"
     gene            complement(5778..7289)
                     /gene="accC"
                     /locus_tag="ACZPB4_08130"
     CDS             complement(5778..7289)
                     /gene="accC"
                     /locus_tag="ACZPB4_08130"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008025628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0004075 - biotin carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HIR1098225.1"
                     /translation="MIKKVLVANRGEIAMRIFRTCRVMNIPTVAIYTHVDRGALHVRY
                     AEEAYCISEDEADTSYLKPDLILEIAKKTGAAIHPGYGFLSENADFARRCEEEGVIFI
                     GPSADVIAKMGIKTEARKIMKEAGVPVVPGTEKPVTDIEDAKKVAAEVGYPIMLKALA
                     GGGGKGMRLVHSEDEMEAAFRMSRSEAANSFGNDAIYIEKYIENPHHIEVQVLGDKYG
                     NVIHLYERECSIQRRNQKVIEEAPSPFVKEAARQKMLAVAVEACKKIGYYSAGTLEFM
                     MDKDQNFYFLEMNTRLQVEHLVTEETTGVDLVRDMILVAAGNRLPYKQEDVACRGHAL
                     ECRIYAEDPENNFMPSPGVIKVREAPEGRNVRLDSAAYAGFEVSLHYDPMIAKLCTWG
                     RTRESAISNMIRALREYKILGIKTTIPFHLRVLHNETFLKGNYDTTFIDTKFDKEDLK
                     RRQNSDPTVAVIAAALKHYEEEKEAAARATTVPLVGESLWKHYGKLQMLANNF"
     gene            complement(7302..8846)
                     /locus_tag="ACZPB4_08135"
     CDS             complement(7302..8846)
                     /locus_tag="ACZPB4_08135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015532945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA carboxylase subunit beta"
                     /protein_id="HIR1098226.1"
                     /translation="MKEKIEQLKALNHKAELGGGEDRIAKQHAAGKLTARERIELLLE
                     KGSFVEIDKFVTHTCHEFGLEKQRPLGDGVVTGYGMIGQRTVFVFAQDFTVFGGALSE
                     TYARKICKIMDMATELGAPVIGLNDSGGARIQEGVRSLAGYAEIFLRNSLASGVIPQI
                     SAIMGPCAGGAVYSPALTDFIFMVKQTSYMFITGPEVVKSVTQEEVTMENLGGSEVHS
                     TRSGVAHCTADNDMDCILKIRELMSFLPNNNMEEPPFVPTTDSPNRIDPQLDLLVPTN
                     PNQPYDMKELILSVADDQNFFEIQEEYAKNIIIGYIRLNGKTIGVVANQPAALAGTLD
                     INASVKAARFVRFCDAFNIPLLTLVDVPGFLPGVNQEYEGIIRHGAKLLYAYCEATVP
                     KVTVITRKAYGGAYDVMSSKHIRGDINFAYPTAEIAVMGPDGAVNILFRKDLKTAEDP
                     EGKRKELQADYREKFANPYRAAELGYVDEIIEPSITRSRLIRSFELLANKRQSNPPKK
                     HSNIPL"
     gene            complement(8988..9821)
                     /locus_tag="ACZPB4_08140"
     CDS             complement(8988..9821)
                     /locus_tag="ACZPB4_08140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004620 - phospholipase activity [Evidence
                     IEA];
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase A"
                     /protein_id="HIR1098227.1"
                     /translation="MKKTIISFLFLLVCGMAHSQVLAKGPEESYNADSIRAILDKSPY
                     FTLFKDNYFIGGIPIGNKPTARNSDVKFQLSIAQRLTKSKLPFDTYLFLQYTQKAFWN
                     VFQESLPMRDLNFNPGIGLGHLIVHKNKYIGKGYLMVEHESNGKDSIFSRSWNKITLA
                     AAVLLNKNWEVQFKGWIPIVDGKENKDILKYNGIFQVAANYRTDNRRFNCGVILTKRK
                     TWFSFNTQIELSYKFNNNENQYFFLQYYNGYGENLLEYNQYKSMLRIGFVIKPQDFSI
                     Y"
     gene            9976..11784
                     /locus_tag="ACZPB4_08145"
     CDS             9976..11784
                     /locus_tag="ACZPB4_08145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011965879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MutS family DNA mismatch repair protein"
                     /protein_id="HIR1098228.1"
                     /translation="MEEIYSYYKENIDAYTRRLGNLKKKIHLMGSIRLALVVGAILSL
                     WIFRDESWQWLTGITFAYIIPFALLMWYHNKMYARKVYAETLIKLNEDELKGLDYDFS
                     AFDGAADKISGEHSFCLDLDVFGDRSLFQSLNRTVTGFGRERLAGWLSNPLTDKKEIV
                     KRQEAVKELATLSALRQHFYVTGIIRQDTQDTRDNDINFMDRLTQRKHKFVDSLPWKL
                     LIWAVPVLWIVLGIAYSLDWISGSLLNIYFLITLVIAYGRAKEINALYATVNKMESIF
                     NRYSKLMQCVEEDNFQSEELKEISGQLANEKELASHAIKRLSSYIGGLDQRFSLAGII
                     FNLFYLRDTRHAILLERWIQTYSDKLPFWFDALARFDALNSLGGFAFNHPEYIYPEIA
                     DTYFQMEGKALGHPLLNREVCVKNDIDIRKSPWFLIITGANMAGKSTYLRTIGVNYLL
                     ACVGAPVCAASLTVYPAHMVTSLRTSDSLASNESYFFAELKRLKMIIDRLQNGEKLFI
                     ILDEILKGTNSIDKQKGSLALMKQLVAYKACGIIATHDLVLGTLEEEFPEQIKNYRFE
                     ADIKDEELSFSYQLREGIAQNMNACFLMNKMGILFN"
     gene            complement(11830..12621)
                     /locus_tag="ACZPB4_08150"
     CDS             complement(11830..12621)
                     /locus_tag="ACZPB4_08150"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metallopeptidase"
                     /protein_id="HIR1098229.1"
                     /translation="MRKIASLFVALLLLAGCSSVPLTGRKQVLLVSDQEVLSSSLTQY
                     NDYIKTAKKSTNANKSAMVTRVGKKIAAATEDYLRANGMADEVKNFSWEFNLVNDPQV
                     NAFCMPGGKIVVYEGLLPLVSSDDELAVVIGHEVAHAVAKHSNERMSQQLMAQYGAAI
                     LSAAVSNKSAAVQQAANTVYGVGAQYGVMLPFSRKHESEADYMGLVFMTMAGYNPDVA
                     VNFWQKMSAGKSGSTPEFMSTHPSDATRIAEIQKVLPAIKTKYKK"
     gene            13003..13443
                     /locus_tag="ACZPB4_08155"
     CDS             13003..13443
                     /locus_tag="ACZPB4_08155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0034618 - arginine binding [Evidence IEA];
                     GO_process: GO:1900079 - regulation of arginine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HIR1098230.1"
                     /translation="MSTKKERLDAICGIIQTKVISNQEELLKELEDSGFSVTQATLSR
                     DIKQLKVAKVHDGNGDYVYRLPEESISKQAQPEGKKKPNIEFSGNLAVVKTRPGYAMG
                     IASDIDSHAPSEILATIAGDDTILVIPRNGVSQEKVIAALSHFI"
     gene            13472..14065
                     /locus_tag="ACZPB4_08160"
     CDS             13472..14065
                     /locus_tag="ACZPB4_08160"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIR1098231.1"
                     /translation="MEQEIEIDVMIADASHEVYVDTILDTIESAAKVRGTGIAKRTHE
                     YVAQKMKEGKAVIALAGNEFAGFSYIESWGNKQYVTTSGLIVHPDFRGLGIAKRIKDM
                     TFQLARMRWPKAKVFSLTSGAAVMKMNTELGYVPVTFSDLTDDEAFWRGCNGCVNHDI
                     LERTERKYCICTAMLFDPADPHRAQREREARNQTKKD"
     gene            14104..15303
                     /locus_tag="ACZPB4_08165"
     CDS             14104..15303
                     /locus_tag="ACZPB4_08165"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007653701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004055 - argininosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000050 - urea cycle [Evidence IEA];
                     GO_process: GO:0000053 - argininosuccinate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0006526 - L-arginine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HIR1098232.1"
                     /translation="MKKKVVVAFSGGLDTSFTVMYLAKEKGYEVYAACANTGGFSEEQ
                     LKQNEENAYKLGATKYVTIDVTKEYYEKSLKYMIFGNVLRNGTYPISVSSERIFQALA
                     IARYANEIGADAIAHGSTGAGNDQIRFDMTFLVLAPNVEIITLTRDMALSREEEINYL
                     KEHGFEADFTKLKYSYNVGLWGTSICGGEILDSAQGLPESAYLKQVEKTGSEQLRIEF
                     KNGEVHAVNGEVFEDKIAAIQKIEEIGAAYGIGRDMHVGDTIIGIKGRVGFEAAAPML
                     IIGAHRFLEKYTLSKWQQYWKDQVANWYGMFLHESQYLEPVMRDIEAMLQESQRNVNG
                     TAILELRPLSFSTVGVESEDDLVKTKFGEYGEMQKGWTAEDAKGFIKVLSTPLRVYYT
                     NHKDEEI"
     gene            15300..16268
                     /gene="argC"
                     /locus_tag="ACZPB4_08170"
     CDS             15300..16268
                     /gene="argC"
                     /locus_tag="ACZPB4_08170"
                     /EC_number="1.2.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013545929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003942 -
                     N-acetyl-gamma-glutamyl-phosphate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0070401 - NADP+ binding [Evidence IEA];
                     GO_process: GO:0006526 - L-arginine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0006592 - ornithine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="HIR1098233.1"
                     /translation="MIKCGIIGGAGYTAGELIRLLLNHPDAELTFINSSSNAGNKITD
                     VHGGLYGETDLVFTSELPLDSIDLLFFCTAHGDTKKFMESHTVPENVKIIDLSMDYRI
                     EGPEHDFVYGLPELNRRRICNARHIANPGCFATCIQLGVLPLAKHLMLNSDLHVNAIT
                     GSTGAGVKPSSTSHFSWRNDNISIYKPFTHQHLAEINQSLSQLQKSYSSRINFIPVRG
                     NFSRGIFATTYIDCKIDLVEIRRIYEEYYDDHSFTFITDKNPDLKQVVNTNKCLIHLQ
                     KIDDKLLIISMIDNLLKGASGQAVHNMNLLFGLEETVGLHLKPSAF"
     gene            16283..17410
                     /locus_tag="ACZPB4_08175"
     CDS             16283..17410
                     /locus_tag="ACZPB4_08175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011965878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate aminotransferase family protein"
                     /protein_id="HIR1098234.1"
                     /translation="MNLFDVYPLFNIEIVQGKGCHVWDSEGNEYLDLYGGHAVISVGH
                     SHPTYVKAITEQVNKLGFYSNSVINSLQQKLADKLGKASGYDDYSLFLINSGAEANEN
                     ALKLASFHNGKKRVIAFKHAFHGRTSAAVRVTDNPKIIAPVNEDLAVTYLPLNDASAV
                     EEELKKGDVSSVIIEGIQGVGGIQLPTDDFMRELRNLCTTYDACLILDEIQSGYGRSG
                     KFFAHQYAGIKPDLISVAKGIANGFPMGGLLISPKFKPVYGMLGTTFGGNHLACAAAI
                     AVLDIMEDERLIDNAAKVGAYLLEELHKLPGIKEIRGRGLMIGIEFEESIKEVRSKLL
                     FEEKVFTGVAGTHTIRLLPPLCLTMDEAKEFIRRFKKVLNA"
     gene            17595..18197
                     /locus_tag="ACZPB4_08180"
     CDS             17595..18197
                     /locus_tag="ACZPB4_08180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011965877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4369 domain-containing protein"
                     /protein_id="HIR1098235.1"
                     /translation="MKYLFIGVFTLLCLFACQSNDSKYIIEGTLPTAQQDGEWIYLAP
                     MENASIENIDSTRIENARFTFQGTGEEMKVLRMRILLRLKFQELLVVTEPGVTSVRID
                     SISSASGTPQNDALQHWKDRKQKTDSESYALWTALKTCSPEDSIRIKQTWDSLRVETQ
                     AFNYAFMKEHINQTVGKFLYKMIKTSLTEELRKELDEANH"
     gene            18181..19746
                     /locus_tag="ACZPB4_08185"
     CDS             18181..19746
                     /locus_tag="ACZPB4_08185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6057 family protein"
                     /protein_id="HIR1098236.1"
                     /translation="MKRIIKQDLSITLAVLAIAIFAFFFWMYPYHLFHKEQMMLFLYS
                     GEFLRGYFQEEAWLACLTGDFLTQFFYYIGGGPFILSVVLTLFALLTYRTFRQFVSKR
                     YALPLMILLVLWEAGRSCGLAYPLSATLSLIGAEGVFLLYSRSQTEGQRLLTCIPAML
                     LCYWCFGYGAWLCLALMLAAGIIAHHQKLSALLAAGILLLPATQYPATTWWSKPDLDR
                     EYVLSLDVEHYFGNIQKMRKHLETDRQILWVTYYRNLYNATHPSEINSPVSLSRNLLA
                     WNQPGTNGLILPVNPSASFLSILFANELWFTLGDMTMAEHCAMLSMIFSPRNSGSRMI
                     KRLAEINLVNGDDEAALKYLRILDKTLLHKSWAEKRIPGQQTPRVKEWLEKKRRDIPT
                     QDHLRSGNDAVTSLRNLVASNAGNLRAYEYLLCYHLLSKDLRSFVEDYVPGKVSSSIF
                     AEALLIHLARQGNIRAEELIKYQIPVKIAKEFADYTRLYEAKDTSLKEKYGKTYWFYY
                     HFATTEPGKESKP"
     gene            19743..21215
                     /locus_tag="ACZPB4_08190"
     CDS             19743..21215
                     /locus_tag="ACZPB4_08190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolB family protein"
                     /protein_id="HIR1098237.1"
                     /translation="MKEARIMKENITYYLVWIICLLAGCTPTPKQIEDTTDPIPMYPD
                     YTDIMIPTNIAPLNFLLRNDADAMQVTLKGKSKEIQLSFGKKAIFPLNLWESLLEQEV
                     GNRLQITVVARIKGKWFRYPSFYWQVVPEKLDSYISYRLIEPGYEVWNKIQLCEREIN
                     TFEERVIADNKDTDGSCMNCHIYGNKKGSLSMFHLRGKQGGTLLNRNGHLRKLKLSND
                     SLPNGAVYGDFHPSGQFAVFSTNIIIPAFHSLGSKRLEVYDTTSDLVVADFRKKQLIT
                     SPLTSRKDELETFPTFSPDGNWIYYCSAPIQPLPDSIHNLKYSLCRISFHKDTKEWGR
                     QIETVWDAQKHNGSACHPKISPDGKYLLFTVADYGTFPIWHQETDLHMMNLQTGKIDT
                     LPAVNSDKSDTYHSWSSNSHWFVFASKRDDGLYGKPYFSYVDSTGKAYKPFVLPQEDP
                     EHYDITLKSYNIPELSTSELPFDAEDVQDIYYDEEAETFK"
     gene            21223..22992
                     /locus_tag="ACZPB4_08195"
     CDS             21223..22992
                     /locus_tag="ACZPB4_08195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6057 family protein"
                     /protein_id="HIR1098238.1"
                     /translation="MENTRKYRYIRGIASLLFGCAICLFWGLYYPHHLHYHEQFQLFL
                     FTPEYGIDKCLHPGGIAEYIAEFLTQFYYFAWAGATILAIVLVLIQRQINWLAQQMGA
                     SDFWYPFSFLPSILLWVFLCDENALLAFPVSITLALFALIIQRKITHPWGRIIYTLLI
                     MPVLYWIVGGGAYFIFVIGVAIGHCIKPVPIVSNKSYIWIPIYILLGILCPLLAQSLT
                     QYPLLSLMTGIDYYRFPMIVPNTLLLVIATVAITPGALALLPPPVKSTKAWMGIISTL
                     LLIGGGTWIYAASNSDKEEAMKYDYLTRMKQWNQIIKAAENKEPNSPFSVTCLNLALA
                     KTGQLGDRMFHFYQNGTEGLIPTFQRDFTSPLPTSEIFYHLGMINSSQRYMFEAMEAI
                     PDYKKSGRAYMRLAETNLINGQYAVAAKYLRALQHTLFYKKWATNAMSYLNNDEKIEK
                     HPEWGWLRKARYTEDFLFSDTEMDVMLGLLLQHNKSNRMAFEYMLTYVLQKKDLERFM
                     KYYPLGKDLGYNHIPISYQEALIFIWTQQHPNFQGLPWSISRNVLEGVSEFARVYMTQ
                     KDSEPILRPKYEKTFWYYLLFRK"
     gene            22999..24465
                     /locus_tag="ACZPB4_08200"
     CDS             22999..24465
                     /locus_tag="ACZPB4_08200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011965874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolB family protein"
                     /protein_id="HIR1098239.1"
                     /translation="MRKLILLYSICIALFTACGNSVVSPEQIEKYPSIYPDYIGVTIP
                     ATIAPMNFSYTDTSYERIDVIVKGCQGKEVHINAKHVNFSEKEWEQLLISNQGDSLLF
                     TVSIKQEGKWSTYKPFPMYISPHPIDYGLVYRKIAPGYEVYSRMGIYERDLSSHKERP
                     LVENTLVKGMCVNCHAFNRTDPSHFSLHIRGTHGATFMRTDNKDEYLNTKTDQTIAAC
                     VYPYWHPGGEYIAYSTNNTRQSFHTVKDERVEVLDLESDIVVYHPADHRLLLCDSLQK
                     KDRFETFPAFSPDGRTLYFCSAEAKKIPEEYKEIRYNLCSIDFDPSAGTFGSRIDTLV
                     NAEALGKSVSFPRPSYDGKYIMFTLSDYGNFSIWHKEANLWLLDLTSGDLRELSEVNS
                     DDTESFHNWSSNSRWFVFSSRRGDGLYTRLYLASMDENGKISKPFLLPQEDPETYYDR
                     SVYSYNVPDFVNAPILLDTKVFEKRITSKERIQVQVGD"
     gene            complement(24678..24848)
                     /locus_tag="ACZPB4_08205"
     CDS             complement(24678..24848)
                     /locus_tag="ACZPB4_08205"
                     /inference="COORDINATES: protein motif:HMM:NF042877.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6722 family protein"
                     /protein_id="HIR1098240.1"
                     /translation="MGKFFYDLAKLTFAGVVICGVIPLYKNPNDFSQWVMLITGLGGT
                     GMIAVCANRIFK"
     gene            25084..26190
                     /locus_tag="ACZPB4_08210"
     CDS             25084..26190
                     /locus_tag="ACZPB4_08210"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 26 protein"
                     /protein_id="HIR1098241.1"
                     /translation="MKNTKLITMLCLGALIACSPSKKGLEPTSEQVSPRERLIENLRA
                     TPQKGIMFGHHDDTVYGIGWEFDEGGSDVQKVCGDYPAVISFDLGEIELGGDKSLDKV
                     PFEKIRKEIINQYNRGGLVSLSWHPRNPKTGGDAWDVSDHAVVKSILPEGENYEKFQS
                     WLGKVNDFILSLKTSDGTKIPVLFRPWHEHTGSWFWWGQNLCTTDEYKALWRMTADYL
                     NAHGAADQIVYAYSTGTEPRDQASYLERYPGHDLIDVLGFDAYQREDKDFFLKSMDTS
                     LSVIDSIGKANHKIIAITETGYEGVPDSTWWTGTLLPAMEKYPVAYVLVWRNAREKVT
                     HFFGPYPGQASAEDFKKFFENPKTLFASDINLYK"
     gene            26291..27463
                     /locus_tag="ACZPB4_08215"
     CDS             26291..27463
                     /locus_tag="ACZPB4_08215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 130 protein"
                     /protein_id="HIR1098242.1"
                     /translation="MEQFQEKVNELFAKHETLLSRKNIPLEDGNGIFTRYQHPVLTAA
                     HTPIFWRYDLNEKTNPYLMERIGMNATMNSGAIKWNDKYILMVRVEGSDRKSFFAVAE
                     SPNGVDNFRFWDYPVTMPDDLVPATNIYDMRLTAHEDGWVYGIFCAERHDPNAAPGDL
                     SSATATAAIARTKDLKNWERLPDLKTKSQQRNVVLHPEFVNGKYALYTRPQDGFIDAG
                     SGGGIGWALIDDITHAEVKEETIIDQRYYHTIKEVKNGEGPHPIKTPRGWLHLAHGVR
                     GCAAGLRYVLYMYMTALEDPTRPIATPAGYFMAPENEERIGDVSNVLFSNGWIADEDG
                     TVYIYYASSDTRMHVAVSTIDKLVDYCMNTPADGLTTTASVETLKKLIDRNLPLLK"
     gene            27482..28873
                     /locus_tag="ACZPB4_08220"
     CDS             27482..28873
                     /locus_tag="ACZPB4_08220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HIR1098243.1"
                     /translation="MIKLTEKIGYGFGDMASSMFWKLFGAYLMIFYTDVFGLPAAAVG
                     TMFLITRIWDSVFDPIVGVAADRTQTRWGKFRPYLLWLAIPFAVIGVLTFMTPSFGQT
                     GNLIYAYITYSLMMMVYSAINVPYASLLGVMSPLPQDRNTLSTYRMVFAYIGSFIALL
                     LFMPMVRFFSGNSDELADQQHGWTMAVVVIAILCAILFYGCFAWTKERVKPIKEQQGS
                     LKDDLRDLLHNKPWWILLGAGVSALVFNSIRDGATVYYFKYFIIEEAYANVSLFGVSF
                     VLSGLYLAVGQAANIVGVILAAPLSNQIGKKRTYMGSMLIASVLSILFFWLDKTDLAL
                     IFTFQVFISICAGSIFPLLWSMYADCTDYSELKTGNRATGLIFSSSSMSQKFGWAIGT
                     AITGWLLAFFGFQANTVQSEETISGIKMFLSFLPAVGTILSVVFIAFYPLSETKMKEI
                     TATLETKRKETNE"
     gene            28866..30065
                     /locus_tag="ACZPB4_08225"
     CDS             28866..30065
                     /locus_tag="ACZPB4_08225"
                     /EC_number="5.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AGE family epimerase/isomerase"
                     /protein_id="HIR1098244.1"
                     /translation="MNKITEDLQNEVQWELENNILPFWMNRMIDSEYGGFHGQITGNN
                     QRVVHAPKGAILNARILWTFSAAYRLLRKPEYLETATRAKRYLIDKFYDQEFEGIYWE
                     LDYTGQPVQTKKQIYALGFAIYGLSEYNRATGDKEALDYAIRLFKAIEQYSFDPEKNG
                     YMEAFTKDWKLIEDMRLSDKDENEKKTMNTHLHILEPYTNLYRVWKDEHLKKQLRNLI
                     LIFTDKILDHRTYHLNLFFNEDWESKYRIISYGHDIEASWLLHEAAIELGDNEILQKV
                     EPLVQKVAIAAEDGLLANGSLIYEYHPNEKKADTDLHWWVQAENVVGHFNLYQHFGDE
                     PALGTAYTCWKFIQRYLIDKEQGEWHWSVSLDHEINREDDKAGFWKCPYHNGRMCMEI
                     IERLAGE"
     gene            30147..>30877
                     /locus_tag="ACZPB4_08230"
     CDS             30147..>30877
                     /locus_tag="ACZPB4_08230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sialate O-acetylesterase"
                     /protein_id="HIR1098245.1"
                     /translation="MNKFYWMVIGLLLGLVNLRAEIKLPALVSDNMVLQQATKVRLWG
                     NATPNSSLKVRSSWDNTEYTAQVNDQGRWEIWVQTPSASFEKQQLTLKNGQDKIVLHD
                     LLIGEVWFGSGQSNMEMPLRGFWHCPIEGGNHAIATSGKYKNSIRYATIQRVGALEPK
                     DYPVGGEWKVCDPRNAPEFGATAYFFATLLTEVLNVPVGIINCSWGGSTVEGWLPKDI
                     LRNYSDIDLSLAGNDEKIHPMLQPM"
BASE COUNT         8357 a         7755 c         7027 g         7738 t
ORIGIN      
        1 gcggccttct cctccaacgg cctcggataa gctctagagg atgaaggcat acggaacagc
       61 ctcatcgtcc ttcccataca agaaaattcc gacgagaagc ccactttcgg ctcctccgtg
      121 ccgggcaata cggagaggag agtatccatc gctttctgcc cggttaccac gatcgccacg
      181 cattccggta tctgggacaa gaccttttcc ggatcgatcg gccgtaccac ctcaaggaac
      241 ttatcggagg cgttcgcttt caagcggatc acctccatgg cggtatcacc gatcccgatc
      301 cccttctccc ggcagaaagc cttcgccttc tcctcgctga acgccttctt gtctcgcagg
      361 aacgcatcct tgttcccata gaaaatcaag ccaaggatgc gccacatatc attctggata
      421 ttcgggtagt aaaaatccat gctccaacga gcttttggag gcgggaaact tcccagcatc
      481 agcaatctcg tattctccgg gaggaagaag cctagcggat gcagctcggt ggtcatgctt
      541 ccttgttctt tttgagttcc ttcttctggt cctctttcgc cagaagcacg acgttataca
      601 cgaagtccgt gatccattgc tcggagtagc ctagtttctc ggcatactta cgcacgctcc
      661 atgcggcctt ctgcacgctg atatccttcc actcggactt ggtcaagata tcgtgaaccg
      721 tcttcgtcgt catattatac agcaacttct tcaccagcat ggagaagcgg aacttccact
      781 gcatcagatt gccaagcaag ttgaacaagt cattgcagaa accttggaac atgaagaaat
      841 acgtcttgat atcgttctgg ttcttgcagt tcttcttcac cgagctgtcg atctccttga
      901 agaaagcctc gcttaggccg taatcctcca tcaacacctt gcgcacacgg gatttctcgg
      961 cgacacccaa tttgttattc tgggtcggta tcttcaacat gcgtttgaac aaagccatat
     1021 cggcgagcat gttcaagttg gtgataccca agttcacggc cataacggct tgataatata
     1081 cacggattaa agatacgaac tcctccacgg aacctttgcc ggcctcttcc gcctcagata
     1141 cgttcttctt gaatagctta gaaataaaat tcatcgtacg attattaaat agtttcgagc
     1201 cgcaaatata cgaaaactta ccgccaatgc agaataacta ttcaattctc tccaccgtaa
     1261 cctccggaaa ttgctccatc aatagcaaca gtggactttc ctccgtgttt ttacgggcct
     1321 tcaacacgat gctgacgacg tactcgtcct tctcctgatg ccccagtctt ttcatgtcat
     1381 agcttaccag caggaaacct ttctcgtaga taacacgggc gatccggttg atcgcctcct
     1441 tgtcggaggt agagaatacc accaaggaac ttcgcatccc gatgctttta aaaataacgc
     1501 tcaacagctc caacccggcg agcgtcaaca aagtggcggc gataccgagc ccgtacatgc
     1561 ctgagccgac ggccagaccg ataccggcgg tcgcccagat accggcggcg gtagtcaatc
     1621 cccgcacgaa ttgtttctgg atgatgatcg tacccgcccc gatgaaaccg atgccactca
     1681 ccacttgggc ggccacacgg ctcggatcga gacttacgct attctctagg atgacatctt
     1741 ggaagccata ttgggagaca accatgatca acgcgctacc caacgaaaca aggaagtgag
     1801 tccggtaacc cgcctccttc gcacggtact cacggtctag tccgacaacg gcgcccagaa
     1861 tacctgccac gaaaagtctt agtatgaaat cccacatcat aatcaacgat cttttaggtt
     1921 ttaccccgaa agataggaat tatttattga ttcagccgcc attcacggtg ataagaatcg
     1981 atcgcctccc ggacggagcc atgtaggagc aggaggttct tgctctgctc gtaatccaga
     2041 cgaagctctt ccatgatcat acgggtgcca cggtccacca atttttggtt ggtcagttgc
     2101 atattcacca tccggttccc tttcacccga cccaacttga tcatcgtgga ggtcgtgatc
     2161 atattcagca ccatcttctg ggccgtaccg ctcttcatcc gcgtacttcc ggtgacgaac
     2221 tccggaccta ctaccggctc gatggcgatc tccgcctccg ccgccatcgg agagtccggg
     2281 ttgcaggaga tagaggccgt caggattccc tcggagcgtg ccttacgcag ggcgccgatc
     2341 acgtagggag tcgtacccga ggcggctatc cccaccaagg tgtcgttcgt attgatatga
     2401 tattgttgaa gttcctccca agccttatcc agatcgtctt ccgccgactc gacgggattc
     2461 cggagcgccc ggtcgccgcc ggcgatcaaa ccgatcacca aggtattcgg cataccgtac
     2521 gtgggaggga tctcggaggc gtccaagaca cccaagcgac cactcgtacc cgccccgata
     2581 tagaagagcc taccgcctct ccgcatccgc tctacgatac gggttaccag tttctcgatc
     2641 ttcgggatct cccggccaac ggcgatcgcc actttccggt cctcgttatt gatgccttcc
     2701 agcaactccc ggacagacat ctgatccaga ttatcataca acgattccga ctcggttatc
     2761 ttttgaaata ccataactca ttcatttttt tcttcgttcg taaaatgata ccggatcaat
     2821 ccgtccatgg gagcctgtac gaccgtaccg accttcaagc ctaaggataa ggccgccgct
     2881 ttcaatacct cctgataata ataggcgata gagcctacaa aatgaatcgg gtacgtatca
     2941 gctcccggat ataacgccac gttacggagg aaaaagctac ggaaactcgt atagaccaaa
     3001 ttataaatcg gttgctcggt gatattctcc aacaagaaac gggacaaggt agccaagaaa
     3061 cgattcggga aaggttgttt gtatacccgc tccaacaata aggcgggcgt caactcatat
     3121 tgatccataa acttccgaac caaaggcgcc ggcaactgac gcttcaagca atcccctacc
     3181 aataacttcc cgagcacggc gccactaccc tcatccccca gaatgaatcc caagggagag
     3241 atatgctccg ttatctccgt cccgtcatac agacaagaat tcgatcccgt ccccaatata
     3301 caggcgattc ccggacggct cccgcataag gcacgagcag ccgccatcaa gtcactatac
     3361 acctctatgg gagccgggat ataaggcgta atcgcctctt ccacgatccg gttcttctcc
     3421 gggaaggcgc aaccggcgcc atagaagtaa atggcatcga tccgctcacc cttcaaggcg
     3481 ggcaataagg catcccggat ttctccggcg atctcctccc gtgtctggaa gaagggattg
     3541 atacccgccg tcacgaccgt acgcaccggt ctgccttgat ccgccaggca ccactccgtc
     3601 tttgtagatc cgctatccgc aattaatatc atacacttat tataatatca aattctggag
     3661 aatatatacc accgcaccag acaaatatcc cgccaaggcc agcagcgaga tattcttcaa
     3721 gtaccaaatg aaattgatcc gctctaggcc catcacgacg actccggcgg cggaaccgat
     3781 gatcaacata cttccaccta ctcctgcgca ataagccaag aactgccaga acacgccgtc
     3841 ttgcatgaag ttcgccagat aagccggatc agtcgccgca gccaccatag cgtccgtagc
     3901 caccgggtac ataccgatag cacccgctac caacggaaca ttatccacga tagacgataa
     3961 ggcgccgata atcaggttca ccgcatacac attgcctacc gtatcgtcca gccagaaagc
     4021 gaaatccgac aatacgccgc tgcaacgcaa ggcatccacc gccaaaagga ttccgaggaa
     4081 gaataacaag gtcgccccgt ctatacggtg aaccaccttg gacaagcgca atttcaagtc
     4141 ctcgtcgatc ggtttacggg cgtatagcat ctccgtatag aaccaaagaa tacccactcc
     4201 catcaagata cccataaacg ggggaagatg agtaaccgtc ttgaatacag gcacgaacaa
     4261 taaacacaac acaccgatga tcaagatcga taacttctcc ttatccttca atttcttcag
     4321 caactcattg tccgcctcca tttgcgagaa tgcgttaggg ggcgtcacgt tgccatgcaa
     4381 gaaacgcatg gcgatcaaga ccgggatcaa cgccgatacg atactcggca ggatcaaatg
     4441 ggggatcgtg gatgaggtgg agatatttcc ccttacccaa agcatgatcg tagtcacgtc
     4501 gccgatcggt gaccaagcgc caccgctatt cgccgctata ataatgatac tgccgaacac
     4561 ccaccgctct ttataattcc cgagcaactt acggatcaac atgatcatga cgatcgaggt
     4621 ggtaaggttg tccaacacgg ccgacataaa gaacgtgatc acggcgatca acgccagcag
     4681 tttcttcttt ttcttcgtgg taatatgatt cgtgataaac atgaaaccgc catgggcatc
     4741 gatcagctcc acggttatca tcgccccgat caggaatata agtgtctcgg cgatctctcc
     4801 gatactatcc agaacctgat gctccacgac gaaccgggta cattgttcct taaacgttaa
     4861 agaacccaaa gaggggaacg attccaagaa caagctgaat tcctctgccg aggccctcgg
     4921 gatgaaaaac ggggccgcgt acgtgtacat aacccataag accgtaccga taagcaaagc
     4981 cgttcccgcc ttgtttatct ttagaggatg ttccaatgcg atcatcaaat aaccgacaag
     5041 gaacacaatg accattgctg tcaacataac ttcatgattt aggtttaaac gctacaaatg
     5101 tagaaataat aactctgtaa cacgatagaa agacggaatg ttttttaaga taattttacc
     5161 aaacatgcga aaggaaccgg actgctccga ttcctttcct attctctcga gggaaaacta
     5221 taaccccgag acaactcact ctacaaccaa catcttatca cccacggaga ccttgtccgt
     5281 ctcattgaca tacacctctt tcaccacccc atcgatcggc gtacgaatct cgttctccat
     5341 cttcatggca accaatacgc aaagcgggtc tcccgccttg acctcatcgc ctaccttgac
     5401 atataccttc tggatcacgc ccggcatctg ggcctgtatg acctgacggc cgaccgtctt
     5461 ggaactggtt ctcgacaggc gtaatttctt caactcgtca atcacctgta cttggaaata
     5521 atcaccttta ttctttacct cataggtgga atctccaaca ctggatattt gtacgccatg
     5581 agatttatgg ttcatgatga tcgagtggat cgtatctccg cccagattgt aatctacatc
     5641 ataaacggta ccgtttacgg atactttctt gataggcccg tcttccagaa tctctacctt
     5701 gaactctgtg tcgggaatat cgttaaccgt ggcaaaataa gtcgctaaag cctttgacat
     5761 aatcattcct cctctcatta aaagttattg gccaacattt gtaacttccc gtagtgtttc
     5821 cacagggact cccctaccag cggaacggtc gtcgcacggg cggccgcctc tttctcctcc
     5881 tcgtaatgct tcaaggcggc ggcgatcacg gctacggtcg ggtcgctgtt ctggcgacgt
     5941 ttcaagtctt ccttatcgaa cttggtgtca atgaaggttg tatcgtaatt ccccttcaag
     6001 aaggtctcgt tatgcaacac acgcaggtgg aatggaatcg ttgtcttgat tcccaagatc
     6061 ttgtattccc gcaaggcacg tatcatgttc gagatggcgg actcacgagt ccggccccac
     6121 gtgcaaagct tggcgatcat cgggtcgtaa tgcaaggaga cctcgaaacc ggcgtaagcg
     6181 gcgctatcca gacgtacgtt acgtccctcg ggagcctcac gcaccttgat cacacccgga
     6241 gagggcataa agttattttc cgggtcctcc gcgtagatac gacattccaa ggcatgcccc
     6301 cggcaagcca catcttcctg cttataaggc agacgatttc ctgcggccac caagatcata
     6361 tcgcgaacca agtccacgcc cgttgtctcc tccgtcacca gatgctccac ttgaaggcgg
     6421 gtattcatct cgaggaaata gaagttctgg tccttatcca tcatgaactc caacgtcccg
     6481 gcactgtagt aaccgatttt cttgcaagcc tccaccgcta cggccaacat cttctggcga
     6541 gcggcctcct tcacgaatgg agagggcgct tcctcgatca ccttctggtt acggcgctgg
     6601 atagagcact cacgctcata cagatggatc acgttcccat atttatcccc gagtacctgc
     6661 acctcgatat gatgggggtt ctcgatatac ttctcgatat agatggcatc gtttccgaac
     6721 gagttggccg cctcggaacg agacatacgg aaagccgctt ccatctcatc ctcgctatgt
     6781 accaaacgca taccctttcc accgcctccg gcaagcgcct ttagcataat cggataaccc
     6841 acctcggcgg ctaccttctt ggcatcctct atgtccgtca ccggcttttc cgttccggga
     6901 acaaccggca caccggcttc tttcatgatc ttacgggcct cggtctttat acccatcttc
     6961 gcgatcacgt cggcgctcgg gccgataaag atcacgccct cctcctcgca acggcgggcg
     7021 aagtcggcgt tctccgacaa aaagccgtaa cccggatgaa tagcggctcc tgtcttcttg
     7081 gcgatctcaa ggatcaagtc cggcttcaag taagaggtat ccgcttcatc ttccgagatg
     7141 cagtaagctt cctccgcata acgtacatgt aatgctccgc gatccacatg cgtatagatc
     7201 gctacggtcg ggatgttcat cacccggcag gtgcggaata tccgcatcgc tatctcgcca
     7261 cgattggcaa ctaatacttt ctttatcata aggattcgtt tttaaagagg aatattggaa
     7321 tgcttcttcg gaggattgga ttgccgtttg ttggccagca actcaaaact acggatcaag
     7381 cggctgcgtg tgatagacgg ctcgatgatc tcgtctacat agcctaactc agcggcccgg
     7441 tacgggttag cgaacttctc ccggtaatcg gcttgcaatt ccttccgttt gccttcggga
     7501 tcttccgcgg tcttcaaatc cttacggaac aagatattca cggcaccatc cggtcccatg
     7561 acagcgatct cggcggttgg ataagcgaag ttgatatcgc cccggatatg cttggagctc
     7621 atcacgtcgt aagcgccacc gtaagccttt cgggtaatga cggtcacttt cggcacggta
     7681 gcctcgcaat acgcatacaa taacttagcg ccatgacgga taattccctc gtactcttgg
     7741 ttcacgcccg gcaagaaacc cggtacatcc accagcgtca acaacggtat attaaacgcg
     7801 tcgcagaaac ggacgaaacg ggcggccttt acggatgcgt tgatatccag cgtaccggcc
     7861 aatgcggcag gttgattcgc cacgacaccg atcgtctttc cattcaaacg gatataaccg
     7921 ataatgatat tcttggcata ttcctcttgt atctcgaaga agttttgatc atcagccacg
     7981 gaaaggatca actctttcat gtcgtacggc tggttgggat tggtaggaac cagcagatcc
     8041 aattgcggat cgatgcggtt cgggctatcg gtggtaggga cgaatggcgg ctcttccata
     8101 ttattattcg gcaagaacga catcaactca cgtatcttca agatacaatc catatcgtta
     8161 tccgctgtgc aatgagccac tccggaacgg gtgctatgca cttccgagcc tcccagattc
     8221 tccatcgtaa cctcttcttg cgtcacgctt ttcacgacct ccgggccggt gataaacata
     8281 tagctcgttt gttttaccat aaagataaag tccgtcaacg ccggcgagta aaccgctcca
     8341 cccgcacacg ggcccataat ggcgctaatc tgcgggatca cgcccgaagc caacgagttc
     8401 cggaggaata tctcggcgta tcccgccaag gaacgaactc cttcttgaat acgtgcgcct
     8461 cccgaatcgt tcaacccgat caccggagcg cctagttccg ttgccatgtc catgatctta
     8521 cagatcttac gggcatacgt ctcagacaag gctccaccga ataccgtgaa gtcctgagcg
     8581 aaaacaaata ccgtgcgttg cccgatcatt ccgtaaccgg tgaccacgcc atcccctaat
     8641 ggacgctgtt tttctaaacc gaactcatgg cacgtatgtg tcacgaactt gtcgatttcc
     8701 acgaaactac ctttttccaa tagtagttcg attctttctc tagcggttag tttacctgcc
     8761 gcatgttgct tcgcgatgcg gtcttctccg ccccctaact cagctttgtg gttgagagct
     8821 tttaattgtt caattttttc cttcatggcg tatctcttta attatccggg aaacgttcaa
     8881 tatattagaa aacaaagtct gtaaatgtat tgtttcctaa agaaacgaaa tgtatcatat
     8941 attacatcta tcgcccgatc aatgagatct atcaagaagg atatttttta gtaaatactg
     9001 aaatcttgcg gcttgatcac gaaaccgatc cgcagcatgc ttttgtattg attgtattcc
     9061 aaaaggttct caccgtaacc attataatat tgcaggaaga aatattggtt ctcgttatta
     9121 ttaaacttat agctcaactc gatctgagtg ttaaagctga accaagtctt tcgtttggtc
     9181 aagataaccc cgcagttaaa gcgcctgttg tctgtccggt aattggcggc tacttggaat
     9241 ataccattat atttaaggat gtctttattt tccttgccat ccacgatcgg tatccagccc
     9301 ttgaattgaa cttcccagtt cttattcaac aggacagccg ccgctagggt gatcttgttc
     9361 caacttcggg agaagatgct atctttaccg ttcgactcgt gctcgaccat caaatagcct
     9421 ttcccgatat atttattctt atgcacgata aggtgcccca aaccgatacc cggattaaaa
     9481 ttcaagtcgc gcatcggcaa ggactcttga aagacattcc aaaaagcctt ttgcgtgtat
     9541 tgcaagaaaa gataggtatc gaaggggagt ttacttttcg taagacgttg ggcgatgctc
     9601 aactggaatt taacgtcgga gtttctcgcc gtaggcttgt tgccgatagg gataccgcca
     9661 ataaaataat tgtccttgaa taaggtaaaa taaggtgact tatccaaaat cgcacgaata
     9721 ctatccgcat tataactctc ttccggccct ttcgctaaaa cttgcgaatg tgccataccg
     9781 caaacaagaa ggaagagaaa ggatataatc gtttttttca taaatgatct taaattataa
     9841 atgtgtccgc gaatataggg gaaacggcag ttggctttat cgcccaaatt acatgaataa
     9901 tggtcatttc acctatgaat ataatatata aaccaaaatt caagaggtta gttcattttt
     9961 cctatattcg cggctatgga agaaatctat agttattata aagaaaatat cgacgcttat
    10021 acacggcgct tgggtaattt gaaaaagaag atccatttga tggggagtat ccggttggct
    10081 ttagtggtgg gagcgatcct ctccttatgg atattcaggg atgagagttg gcaatggctg
    10141 acggggatca ccttcgctta tatcatcccg ttcgcgctcc tgatgtggta ccataataaa
    10201 atgtacgcac gaaaagtata cgccgagacc ttgatcaaac tgaacgagga tgagctaaaa
    10261 ggactggact atgatttcag cgcgttcgac ggggcagccg ataagatctc gggcgagcac
    10321 tctttctgct tggatctgga tgtgtttgga gaccgctcct tgtttcaatc gctcaatcgt
    10381 accgtaaccg ggttcgggcg ggaacgactg gccggttggc tctcgaatcc cttgacggat
    10441 aagaaggaga tcgtcaaacg gcaagaggct gtcaaggaat tagcgacttt atccgcctta
    10501 cggcagcatt tctatgtgac gggaatcatc cggcaggaca cgcaagatac gagagacaac
    10561 gatatcaact ttatggaccg actcactcag cgtaagcata aattcgttga tagcctaccg
    10621 tggaaactat tgatctgggc ggtcccagtg ttgtggatcg tattgggtat cgcttactca
    10681 ctggattgga tcagcgggag tttattgaat atttatttct taatcacgtt agtgatcgct
    10741 tacggacgag ccaaggaaat caatgcgctt tacgcgaccg tcaataagat ggagtctatt
    10801 ttcaatcggt actcaaagct gatgcaatgt gtggaagaag ataatttcca gtcggaagag
    10861 ctgaaagaga tcagcggaca attagcgaat gagaaggaat tggcctcgca tgctatcaaa
    10921 cgcttgtcgt cgtatatcgg aggattagac caacgattca gtttggcggg tatcattttc
    10981 aatctcttct acttgcggga tacacgccat gccatccttt tggaacgctg gattcagact
    11041 tactccgata aacttccgtt ttggttcgac gcgctggctc gtttcgacgc gctgaactcg
    11101 ttgggtggtt tcgctttcaa ccatccggaa tacatctatc cggagattgc cgacacttat
    11161 ttccagatgg aaggcaaggc tttgggacat cctcttttga accgggaagt ctgcgtaaag
    11221 aacgatatcg atatccgcaa aagtccttgg ttcctgatta tcaccggagc gaatatggcc
    11281 ggaaaaagta catacctccg gacgatcggt gtcaattact tattggcttg cgtaggcgct
    11341 ccggtctgcg ccgcctcctt gacggtttat cccgcccaca tggttaccag cttacgtacc
    11401 tcggattcct tggctagcaa cgagtcttat ttcttcgcgg agttgaaacg gctgaaaatg
    11461 attatcgaca ggctgcaaaa cggggagaag ctatttatca tcttggacga gatcttgaag
    11521 ggaacaaatt ctatcgacaa gcagaaaggc tctcttgccc ttatgaaaca gctggtcgct
    11581 tataaggctt gcggcatcat cgccacccac gatttagtgt tgggtacttt ggaggaagag
    11641 ttcccggaac aaataaagaa ttaccgcttc gaagcggata taaaagacga ggagctatcc
    11701 ttctcttatc aactaagaga aggaatagcc cagaatatga atgcttgttt cttaatgaac
    11761 aagatgggaa tcttgtttaa ttgaaaattg agacaagtga taaaataact gtcacttgtc
    11821 aactgccaac tactttttgt atttggtttt gattgcgggt aggacttttt ggatttccgc
    11881 tatacgagtg gcatcactgg ggtgcgtact cataaattcc ggcgtagagc cactctttcc
    11941 ggcggacatc ttttgccaga agttgactgc cacgtccgga ttgtatcccg ccatagtcat
    12001 gaataccaat cccatataat ccgcttccga ctcgtgctta cgggagaaag gaagcattac
    12061 gccatactgc gctcccacac catataccgt attggccgct tgctgtaccg ccgcactctt
    12121 attgcttacg gccgcactta aaatagccgc cccgtattgg gccattagtt gctggctcat
    12181 acgctcattg ctgtgtttag ctacggcatg ggcgacctca tgcccgatga ctaccgccaa
    12241 ttcatcgtcc gaggaaacca aaggcagcaa tccctcgtac accacgatct tgccgcctgg
    12301 catacagaag gcgttcacct gcggatcatt caccaaatta aactcccaag agaagttttt
    12361 tacctcatcc gccatcccgt ttgcccgcaa atagtcctcc gtagcggcgg ctatcttctt
    12421 tccgacccgg gttaccatag cgcttttgtt cgcattcgtc gattttttcg ccgtctttat
    12481 ataatcgtta tactgggtaa ggctggacga taacacctct tggtccgaaa ccaacagcac
    12541 ttgcttacgt cctgttaacg gtacgctgga acagcctgcc aataaaagca aggccacgaa
    12601 taaacttgct atttttctca tatcctttta cttgaaatta aacctgatac tctcttttta
    12661 ataacgcaaa gatactacca ttttgttcaa aacaaccacc ccctttcgtt ctttctatag
    12721 gaagtattag ccttttcttt caacaacatc catcatctac catctgttgc atgatcatcc
    12781 accaattggt acatgatctt ctaacagctg ttgcatgatc atccaacggc tgatagaaga
    12841 tgaatataaa tagatgaaat gcctaacact tacagtgatt aaacctaagc taagcaggaa
    12901 aatcccttac cccctactta tatcagaaaa aaaagccctt gattgtatat ttattcaaca
    12961 atactcttta tatttgcagc ctgttttgca taaatataca acatgagtac aaagaaggaa
    13021 cgattggatg ccatttgcgg tattatacaa acgaaggtga taagtaatca agaagaactg
    13081 cttaaagagt tggaagatag cggattctcg gttacgcaag ctacgctttc ccgcgacatc
    13141 aagcaactga aagtagccaa ggtacacgac ggaaacggag attatgtata tcgccttccc
    13201 gaagagagta taagcaaaca agcacagcct gaaggcaaga aaaagccgaa tatcgagttt
    13261 tccggaaact tagcggtggt gaaaacacga ccgggttacg ccatgggaat cgcctcggac
    13321 atagactccc atgcccccag cgagatactg gccaccatag ccggagacga tacgatcttg
    13381 gtaatccccc gcaacggtgt gagccaagag aaggtgattg ccgctttatc acattttata
    13441 taaaaggaaa aaactaagaa caaacaataa aatggaacaa gaaatagaaa ttgatgttat
    13501 gatcgctgat gcctctcacg aggtatatgt ggatacgatc ctagatacga tcgagtctgc
    13561 cgctaaagtc cggggcacgg gtatcgccaa acgtacgcac gagtatgtgg cccagaagat
    13621 gaaagagggc aaagcggtga tcgccttggc gggaaacgag ttcgccgggt ttagttatat
    13681 cgagtcatgg ggaaacaagc agtacgtgac tacctccggc ttgatcgtgc atccggattt
    13741 ccggggcttg ggtatagcga aacgcatcaa agacatgacc ttccagcttg cccgcatgcg
    13801 ctggccgaaa gcaaaggtat tcagccttac ctccggcgct gccgtgatga agatgaatac
    13861 cgagctggga tatgtaccgg ttacgttctc cgacttgacg gacgatgagg ctttctggcg
    13921 gggttgcaac ggttgcgtga accacgatat cttggaacgc accgaacgta agtattgcat
    13981 ctgcacggcc atgctgttcg acccggccga tccgcatcgt gcgcaacgag agcgggaggc
    14041 acgtaatcag actaaaaagg actaaattaa tacgatagaa aaacaacata aaatagagaa
    14101 acgatgaaga agaaagtagt agtagcgttc agcggaggtt tggatacctc attcacggtc
    14161 atgtatctgg ctaaagaaaa aggatacgag gtatacgccg cttgcgctaa cacaggtggt
    14221 ttcagcgagg aacaattgaa acaaaacgag gagaacgcct ataagctagg cgccacgaaa
    14281 tacgtgacga tcgacgttac gaaagagtat tacgagaaga gcttgaagta catgattttc
    14341 ggaaacgtgc tgcgtaatgg tacgtatccg atctccgtaa gctccgagcg tatcttccaa
    14401 gccttggcga tcgcccgcta cgcaaacgag attggcgccg acgctattgc ccatggttct
    14461 accggagccg gtaacgacca gatccgtttc gatatgactt tcttggtatt ggctccgaac
    14521 gtggagatta tcacgttgac ccgcgatatg gccttgagcc gcgaggaaga gatcaactac
    14581 ttgaaggagc acggtttcga ggccgatttc acgaagttga aatattccta taacgtaggt
    14641 ctttggggaa cctctatctg cggcggcgag attcttgatt ccgcgcaagg attgcccgag
    14701 agcgcatatt tgaaacaggt ggagaagact ggcagcgagc aattgcgcat cgagttcaag
    14761 aacggtgagg ttcatgccgt gaatggtgag gtgttcgagg ataagatcgc cgctatccag
    14821 aagatcgagg agatcggggc cgcttacggt atcggccgtg atatgcacgt gggcgatacg
    14881 atcatcggca tcaagggacg ggtcggtttc gaggctgccg ctcctatgtt gattatcggg
    14941 gcgcaccgct tcctagagaa atatacgttg agcaaatggc aacaatactg gaaggatcag
    15001 gtagcgaact ggtacggcat gttcttgcac gagagccaat atctggaacc ggtgatgcgc
    15061 gatatcgagg cgatgttgca agagtctcag cgcaacgtga acggtacggc tattctggag
    15121 cttcgtccgt tgtctttctc taccgttggt gtagaatctg aggacgactt ggtgaagacg
    15181 aaattcggtg agtacggaga gatgcagaaa ggctggaccg ccgaggacgc taaaggcttc
    15241 atcaaggttc tttccactcc gttgcgtgtt tattatacga accataaaga cgaagagata
    15301 tgattaaatg cggaattata ggcggagcgg gttacacggc gggtgaattg atccgcctgc
    15361 tcctaaacca ccctgatgcc gagcttacat ttataaacag tagcagtaac gccggtaaca
    15421 agatcacgga cgtgcatggc ggtctttatg gcgagacgga tttggtgttc accagcgagt
    15481 tgccgttaga tagcatcgac cttctgttct tctgtaccgc tcatggcgat acgaaaaagt
    15541 tcatggagag ccacacggtc cccgagaacg tgaagattat cgacctgagc atggactacc
    15601 ggattgaagg cccggagcac gatttcgtgt acggcctgcc ggaattaaac cgccgccgga
    15661 tttgcaacgc ccggcatata gcgaaccccg gttgtttcgc tacttgcatc caattgggcg
    15721 tattgccgtt ggcgaagcac ttgatgctga attccgactt gcatgtcaat gccatcacgg
    15781 gttctacggg agcgggcgtg aagccttctt ccacctctca ctttagctgg cgcaacgaca
    15841 acatatcaat ctataagcct tttacgcatc agcacttggc cgagatcaac cagagcttga
    15901 gccagttgca gaagagttat tcaagccgga tcaacttcat ccccgtacgc ggtaatttct
    15961 cccgtggtat attcgccacg acatacatcg attgcaagat tgacttggtg gagatccgac
    16021 gtatttatga ggaatattat gatgatcaca gcttcacgtt tatcactgat aagaacccgg
    16081 atttgaaaca agtggtaaat acgaataaat gcttgatcca cttacagaaa atagatgata
    16141 agcttcttat tatctctatg atcgataact tattgaaggg tgctagcggc caagcggtcc
    16201 acaacatgaa cttattgttc gggttggagg agacggttgg cttacactta aaaccctccg
    16261 cgttttaaaa aatactataa agatgaattt attcgacgta tatccattat ttaatataga
    16321 gatcgtacaa ggcaagggat gtcatgtatg ggatagcgag ggaaacgagt acctcgactt
    16381 atatggcggc catgccgtga tctcggtggg gcacagccac cctacttacg taaaggcgat
    16441 taccgagcag gtaaataaat taggctttta ctcgaactcg gttatcaata gcttgcaaca
    16501 aaaattagcg gataagctag ggaaggcttc cggctacgat gattattcgt tgttcttgat
    16561 caactccgga gcggaggcga acgagaacgc gttaaaactc gcctcttttc ataacgggaa
    16621 gaagcgggtg atcgcattca agcacgcctt tcatggacgt acctccgccg ccgttcgtgt
    16681 cacggataac ccgaagatca tcgctccggt aaatgaggat ctagcggtta cttatcttcc
    16741 attgaacgac gcttccgccg tagaggaaga gttgaagaag ggggatgtat cgtccgtgat
    16801 catcgaaggt atccaaggtg taggtggcat ccaattgcca acggatgatt ttatgcgtga
    16861 gttacgcaac ctgtgtacga cttatgatgc ctgtctgatc ttggatgaga ttcaatccgg
    16921 atatggaaga agcggtaaat tcttcgcaca tcaatatgcc ggtatcaagc cggatttgat
    16981 ctcggtagcg aaaggtatcg ccaatggctt cccgatgggt gggttattga tcagcccgaa
    17041 attcaagccg gtttatggta tgctcggcac tactttcggc ggtaaccatt tggcttgcgc
    17101 agccgctatc gccgttctcg atattatgga agacgagcgt ttgattgata acgcggcgaa
    17161 agtgggtgcc tatttattgg aagagcttca taaacttcct ggtatcaagg aaattcgggg
    17221 ccgtggtttg atgatcggta tcgagttcga ggaatctatc aaggaagtac gtagcaaact
    17281 tctctttgag gagaaagtgt tcacgggcgt agccggaacc catacgatcc gtctgcttcc
    17341 tccgctttgc ttgacgatgg atgaggccaa ggaatttatc cgtcgcttca agaaagtcct
    17401 aaacgcttaa ttgttcttta tttcataaaa agggaggatg tctgaattag tgtcctcctt
    17461 ttttccattc ctccccaaca gcgacgtaaa ttaagtatca ccctttgtca aaaaaacatc
    17521 attccctttt ccgaaaaaat actaacttta cgcagtctaa actttgagtc tctaattact
    17581 aatgaacacg atcgatgaaa tatctattta taggagtatt cactttattg tgcctatttg
    17641 cctgtcaatc taacgattcc aaatacatca tagaaggcac cctacccacc gcacagcagg
    17701 atggggaatg gatttatctg gcacccatgg aaaacgcctc aatcgaaaat atcgattcta
    17761 cgagaataga gaacgcacgg tttactttcc aaggaacggg agaagagatg aaagtcctcc
    17821 gtatgcgcat ccttttgcgt ctcaagttcc aagagctact ggtcgtaacg gaaccgggtg
    17881 tgacctcagt acggatagac tccatcagct cggcctccgg tacaccgcaa aacgacgcct
    17941 tgcagcattg gaaagaccgg aagcaaaaga ccgatagcga atcctatgcc ctatggacag
    18001 cgcttaagac ttgctcgccg gaagattcca tccgcatcaa gcagacatgg gattccttga
    18061 gagtagagac gcaagctttt aattatgcgt tcatgaaaga acatatcaac caaacggtcg
    18121 ggaaattcct ctataagatg ataaaaacct ccttgaccga agagctacga aaggaactgg
    18181 atgaagcgaa tcattaaaca ggatctgtcg atcacgctag cggtactggc gatagcgatc
    18241 ttcgctttct tcttctggat gtacccctat catttgttcc acaaagagca aatgatgctg
    18301 ttcttgtaca gcggcgagtt tctccgtgga tattttcagg aggaagcgtg gctggcttgt
    18361 ctcaccggcg atttccttac gcaattcttt tattatatcg ggggaggccc gttcatccta
    18421 agcgttgtct taactttatt tgccctgctt acctatcgga cattccggca attcgtcagc
    18481 aagagatacg cccttcctct tatgatacta cttgtattat gggaggccgg aaggtcttgc
    18541 ggactcgcct atccgttatc cgcgactctc tccttgatcg gagcagaagg tgttttcctg
    18601 ttatatagcc ggagccaaac tgaggggcaa cgtcttctta cctgcattcc cgccatgctt
    18661 ctttgctatt ggtgcttcgg gtacggggca tggctctgtc tggcccttat gctggccgcc
    18721 ggaatcatag cgcaccatca aaagctaagt gccctgcttg cggcaggtat attacttctt
    18781 ccagcgaccc aatatcccgc taccacttgg tggagtaagc cggatctcga ccgggagtat
    18841 gtactcagcc tcgatgtgga acattatttc ggaaatatac aaaagatgag gaaacatctc
    18901 gagacagacc gccaaatcct ttgggtgacc tattaccgga acctgtacaa tgccacgcat
    18961 ccgtccgaga tcaactcacc cgtatctctc tcccggaacc tcctagcgtg gaatcaaccg
    19021 ggtacgaatg ggttgatcct ccccgtgaac ccatccgctt cttttctctc tatcctattc
    19081 gccaacgagt tatggtttac gttaggagat atgaccatgg ccgagcattg cgccatgcta
    19141 agtatgatct tctctccccg caattcgggt agccgtatga tcaaacggct ggctgagatc
    19201 aatctggtca atggggatga tgaggcagct cttaaatatc tacgtatatt agacaagaca
    19261 ctccttcata aaagctgggc cgaaaagaga atacccggtc agcaaacccc gcgagtaaag
    19321 gagtggctgg agaagaaacg cagagacatc ccgacccaag accatctacg ttccggtaac
    19381 gatgccgtga cttccttacg gaacttagtc gcctcgaacg ccggcaatct ccgtgcttac
    19441 gaatacttac tctgctatca tttactctct aaagatctcc gttcttttgt agaagattat
    19501 gtaccgggta aggtctctag ttccattttc gccgaggccc tgctgatcca tctcgcccgc
    19561 caaggtaata tccgtgcgga agagcttata aaataccaaa tcccggtaaa gatagcgaaa
    19621 gaattcgccg attatacccg gctttatgag gcaaaggaca cgagtttgaa agagaaatac
    19681 ggcaagacct attggttcta ttatcatttt gcgaccacag agcccggaaa ggagagtaag
    19741 ccatgaaaga agcaagaatc atgaaagaga acataaccta ttacctcgtc tggataatct
    19801 gcttgctggc aggatgtacc cctaccccga agcaaataga ggataccaca gacccaatcc
    19861 ccatgtatcc cgattatacg gatatcatga ttcccacgaa tattgcccct ctcaacttct
    19921 tattgagaaa cgatgcggac gctatgcaag taaccttaaa agggaaatca aaagagatac
    19981 aattatcttt cggaaagaaa gctattttcc ctttaaacct atgggaaagc cttttagagc
    20041 aggaagtggg caaccgcctg caaataaccg tagtcgcccg tatcaagggt aaatggtttc
    20101 gttacccctc tttctactgg caagtagttc cggagaaact ggatagttac ataagctacc
    20161 ggcttataga acccggctac gaggtatgga acaagatcca attatgcgag cgggagatca
    20221 ataccttcga ggaacgggtt attgccgaca acaaagatac cgacggttct tgcatgaact
    20281 gccatattta cggaaataag aaaggaagtt tatccatgtt ccatttacgg ggaaagcaag
    20341 gaggcaccct gctgaaccgt aacggacatt tgaggaagtt gaaattgagc aacgacagtc
    20401 tgccgaatgg ggctgtctat ggcgatttcc atccatcggg gcagttcgcc gttttttcca
    20461 cgaatattat catccctgct tttcattcgt taggaagtaa gcggttggaa gtctatgaca
    20521 caacctccga cctagtggtc gccgatttca gaaagaaaca actcatcacc tccccattga
    20581 ctagccggaa ggatgagtta gagaccttcc ctaccttttc gcccgatggg aactggatct
    20641 attattgctc cgctcccatc cagccgttgc ccgatagcat ccataaccta aaatattccc
    20701 tatgccgcat atctttccat aaagatacca aggaatgggg ccgacagatc gaaaccgtat
    20761 gggatgccca gaagcataat ggctccgcct gccatcccaa gatatcgccc gacggtaaat
    20821 acctactttt cacggtagcc gattatggaa ccttcccgat ctggcaccaa gaaacagacc
    20881 tgcatatgat gaacctccag accgggaaga tagatacctt acctgccgtc aactccgata
    20941 aatcggatac ctaccatagt tggtcctcta acagccattg gtttgtcttt gccagtaagc
    21001 gggatgacgg actatacgga aagccttatt tctcttacgt ggatagtacg ggaaaagcct
    21061 ataaaccttt cgttctcccg caagaggatc cggaacatta cgatatcacg ttgaaatctt
    21121 ataatatacc tgaattatcc actagcgagc ttcctttcga cgctgaagat gtacaagata
    21181 tctactacga cgaggaagct gagactttta aataatagaa tcatggaaaa tacacgtaaa
    21241 tatagataca taagaggaat cgcctcctta ttattcggct gtgcgatttg cctgttttgg
    21301 ggactttatt atcctcatca tttacattac cacgagcaat tccagttatt cctgttcacg
    21361 ccggaatatg gaatcgacaa atgtctccat cccggaggca tcgctgaata tatagcggag
    21421 ttcctgacgc agttctatta tttcgcttgg gcaggggcta cgatcttggc gatcgttctc
    21481 gtgcttatcc aacggcaaat aaactggctg gcccaacaaa tgggggcttc cgacttttgg
    21541 tatccgttca gctttctccc ctctatcctg ctctgggtat ttttatgtga tgagaatgcc
    21601 ctgctggcat tccctgtctc cataactctc gccctcttcg ccttaatcat ccagcgaaaa
    21661 atcactcatc catggggacg aataatctat acgctcctaa taatgccggt actctactgg
    21721 atcgtaggtg gtggggccta tttcatcttc gttatcggag tagcaatcgg gcattgcatc
    21781 aaacccgtac caatcgtatc caacaaatcc tatatatgga ttcctatcta catcttgctt
    21841 ggaatcctat gccccctatt ggcacaaagc cttacgcaat atccattgct tagcctcatg
    21901 accggcatcg attattatcg tttccccatg atcgttccca acaccctgtt acttgttatt
    21961 gctaccgttg ccataacccc cggggcactt gctttacttc ccccacccgt aaagagcact
    22021 aaggcatgga tgggtattat ctccaccctg ctccttatcg gtggtggcac atggatctat
    22081 gccgccagca attcggataa ggaggaggct atgaaatacg actacctcac ccgcatgaaa
    22141 caatggaacc agatcatcaa ggcggcggaa aacaaagagc ctaattctcc tttctccgtg
    22201 acctgcttaa atctggctct cgccaagacc gggcaattag gggatcgcat gttccatttc
    22261 taccaaaatg gaacggaagg attgatcccc accttccaaa gagatttcac ctcaccgctc
    22321 cctaccagcg agatattcta tcatctggga atgatcaact cctcacaacg ctatatgttc
    22381 gaagcgatgg aggctatccc cgactataag aaaagcggac gtgcctatat gcgtctggcc
    22441 gagaccaact tgatcaatgg acaatacgct gtcgccgcca aatacctgcg ggctttgcag
    22501 cataccttgt tctataagaa atgggcgacc aacgccatga gctatctaaa taacgatgaa
    22561 aagatagaga agcatcccga atggggatgg ttgagaaaag cccgatatac agaagatttc
    22621 ttgttcagcg acacggaaat ggatgtcatg ctaggcttat tgctgcaaca taacaaaagt
    22681 aaccggatgg ctttcgagta tatgttaacc tatgtcttgc aaaagaagga tctggaacgt
    22741 ttcatgaaat attatccgct gggaaaagat ctgggctata accacatacc catctcttat
    22801 caagaggcat tgattttcat ttggacacag cagcatccta atttccaagg ccttccttgg
    22861 agcatctccc gcaacgtatt ggaaggggta agcgagttcg cccgtgttta tatgacgcag
    22921 aaagactccg agcctatcct tcgcccaaaa tacgagaaga cattttggta ttacttatta
    22981 ttcagaaaat aaacggccat gagaaagctt atcttattat atagtatatg tatagcgtta
    23041 tttaccgctt gtgggaattc ggtagtatcc cccgaacaaa tagagaaata cccgtccatc
    23101 tatccggatt atatcggggt gacaataccc gccacgatag cacctatgaa tttctcttat
    23161 acggatacct cctatgagcg gatagatgtt atcgtaaaag ggtgccaagg caaagaggtg
    23221 catataaacg cgaagcatgt caatttctcg gaaaaagagt gggaacaact gctcatctcc
    23281 aatcaaggcg atagtttact ctttactgtc agtatcaagc aagagggtaa atggagtact
    23341 tacaaacctt tccccatgta catcagcccc cacccgatcg attacggctt agtataccga
    23401 aagatcgctc ccggttatga agtctacagc cgtatgggta tttatgagcg tgatctatcg
    23461 tctcataaag aaaggccttt ggtggaaaac acgctggtca aaggtatgtg cgtaaactgc
    23521 catgccttta accgtacgga cccgagccat ttcagtcttc acatccgagg aacgcatgga
    23581 gccactttta tgagaaccga caataaggat gaatacctca acacgaaaac agatcagaca
    23641 atcgccgctt gcgtctatcc ctactggcat cccggaggcg aatatatagc gtattccacg
    23701 aacaacaccc gacaatcgtt ccatacggtt aaggacgagc gggtagaagt attggatttg
    23761 gaatctgata tagtcgttta ccatccggca gatcatcgtc tactcctttg cgattctttg
    23821 caaaagaaag acaggttcga gaccttccct gcgttctccc cggatggtcg tacgctttac
    23881 ttttgttccg ccgaagctaa aaagattccc gaagaatata aagagataag atataattta
    23941 tgtagtatcg attttgatcc ctctgccggt acattcggga gccgtatcga tacgttggtg
    24001 aacgctgagg ctttagggaa aagcgtatct tttccccgcc cttcctatga cggcaaatat
    24061 attatgttca ccttatccga ttacggaaac ttttcgatct ggcataaaga ggcgaatcta
    24121 tggttactgg acttgacaag cggagacctc cgcgagctat ccgaagtaaa tagcgatgat
    24181 accgaaagct ttcacaactg gagtagcaac tcccgctggt ttgtcttcag tagccgccgg
    24241 ggtgacggcc tttatacccg cctttatctg gcaagcatgg atgagaatgg caagataagc
    24301 aagccctttc tccttcccca ggaagatccg gaaacctatt acgatcgctc tgtctattcc
    24361 tataatgtcc cggatttcgt caatgcccct attctgctgg acacgaaagt atttgagaag
    24421 aggataactt caaaagagcg tatacaggtt caagttgggg actagaaacc aagggttacc
    24481 aaaaacaata cacggatctt atagaaaaaa taaataattc cataagatcc gtgtattggg
    24541 tatagttcta tatctagatg ttcgctatag gttcttcagc catttcttac cggatttggt
    24601 ataagtccat gcaagaaata tccccattac cacgataata attaaaaaca aaaatgtcat
    24661 gttattcata tctgttatta tttaaatatt ctatttgcac aaaccgcaat cattcctgta
    24721 cctcctaaac ctgttatgag cattacccac tgtgaaaaat cattcggatt cttatacaac
    24781 gggataaccc cacatataac tacacccgca aaagtcagtt tcgccaaatc ataaaagaac
    24841 tttcccaaat tctcctttcg ggctttctct cattctctcc cttccttcac ttgttcttgt
    24901 aaatcattcc attttcccat agtcattcta tttgattaat taacatgcac aaagataaca
    24961 atgaattcca aatcaaacaa ccgttccggt taaaatgaaa ataatatcgc tatcagataa
    25021 aataatacta gattgtctgc ccgatacctc ttacattcgc gttcataaag aaagacagtt
    25081 atcatgaaga acacgaaatt aattaccatg ttatgcctag gggcactaat cgcctgttca
    25141 ccgtcgaaga aaggactaga accgacaagc gaacaggttt cgccgagaga acgtttaata
    25201 gagaacctac gtgcgactcc acaaaaagga atcatgttcg gacatcacga tgatacggtt
    25261 tatgggatcg gatgggaatt tgacgaagga ggctcagacg tgcaaaaagt atgcggcgat
    25321 tatccggccg ttatcagctt tgatcttgga gagatcgaac tcgggggaga taaaagcctt
    25381 gataaagtac ctttcgagaa aatacgcaag gaaatcatca accaatataa ccggggaggc
    25441 ttggtatctt taagttggca tccccgtaac cctaaaaccg gaggggacgc ttgggacgta
    25501 tcagaccatg ctgtcgtgaa atcgatcctt ccggaagggg agaactatga gaaattccaa
    25561 agttggctag gcaaagtgaa tgatttcatc ctttccttga aaacaagcga tggcaccaag
    25621 attcccgtcc tattccgtcc ttggcacgaa cacaccggaa gttggttctg gtggggacag
    25681 aatttatgta ccacggatga atacaaggcg ctatggcgaa tgaccgccga ttatctaaac
    25741 gctcacggag cggcagacca gatcgtttac gcttattcca caggtacgga gccgcgggat
    25801 caagcgtctt atctggaacg ttaccccgga catgacttga tcgacgtcct aggcttcgac
    25861 gcttaccaac gggaagataa ggatttcttc ttgaaaagca tggataccag tctttccgta
    25921 atagacagca taggcaaagc caaccataag atcatagcga tcacggagac cggctacgaa
    25981 ggggtaccag actccacatg gtggacggga accctgctgc ctgccatgga gaaatatccg
    26041 gtcgcttatg tattggtatg gagaaacgcc cgtgaaaaag tcactcactt ttttggccct
    26101 tatcccggac aagcctctgc cgaggatttc aagaagttct ttgaaaatcc gaaaacattg
    26161 ttcgcctccg atatcaacct atataaataa catcatacat aaaccagata aatcacgtca
    26221 tatccagttg tagagacggg gcgtgccccg tctcccacca tctgataata tcatttaaag
    26281 caaaaacatc atggaacaat ttcaagaaaa agtaaacgaa ctcttcgcta aacacgaaac
    26341 cttgttaagc cggaaaaata tccctttaga agacggaaac ggaatcttca cccgttatca
    26401 acaccctgta ctgacagccg cgcatacccc gatcttctgg agatatgact taaatgaaaa
    26461 gacaaacccc tacttgatgg aacgcatcgg catgaacgca accatgaact ccggtgcgat
    26521 caaatggaat gacaaatata tattaatggt acgtgtagaa ggaagcgacc gtaaatcctt
    26581 cttcgccgta gccgaaagcc cgaacggagt agacaatttc cgcttttggg attacccggt
    26641 aaccatgccg gacgatcttg tcccggccac gaatatttac gacatgcgcc taaccgctca
    26701 tgaagacggc tgggtttacg gaatcttttg cgccgagcgc catgacccga acgcagctcc
    26761 cggagatcta tcctcggcaa ccgccacggc agctatcgcc cggacaaaag acttgaaaaa
    26821 ctgggaacgt ctcccggatt taaagaccaa gagccaacaa cgtaacgtcg tattacatcc
    26881 ggaattcgta aatggtaaat acgcccttta cacccgcccc caagacggat ttatcgacgc
    26941 aggaagtggc ggtggtatcg gatgggcctt gattgatgat atcacgcacg ccgaagtcaa
    27001 ggaagaaacc atcatcgacc aacgttacta ccatacgatc aaggaagtga aaaatggcga
    27061 aggcccccac ccgatcaaga caccgagagg ctggttacat ctcgcccatg gcgtacgggg
    27121 atgcgccgcc ggattacgtt acgtgcttta tatgtatatg accgcattgg aagatcccac
    27181 gagacctatc gccacacccg ccggctattt catggctccg gaaaatgagg aacggatcgg
    27241 cgatgtatcc aacgttttat tctctaacgg atggatcgcg gatgaggatg gaaccgtgta
    27301 tatttactat gcgtcttccg atacccgtat gcacgtggct gtatccacaa tcgataaatt
    27361 ggtagattac tgcatgaaca ctccggccga cgggctgact acgaccgcat ctgtcgagac
    27421 gctgaaaaag ctaatcgatc gaaatcttcc actcctgaaa taacctacaa aaaccactca
    27481 tatgattaaa ctaacagaga agataggcta cggtttcggg gacatggcat cgtccatgtt
    27541 ctggaaactg tttggcgctt acttgatgat tttctatacg gacgtattcg gattaccggc
    27601 agcagccgta ggtacgatgt ttttgataac tcgtatatgg gactcggtct ttgacccgat
    27661 tgtcggcgtt gcggcggatc gtacgcaaac acgctgggga aaatttcgcc cttatttgct
    27721 ttggctggcg atcccgttcg ccgttatcgg agtgctcact ttcatgactc cttctttcgg
    27781 acaaacaggt aatttgatct atgcctatat cacctattcc ttgatgatga tggtgtactc
    27841 cgctataaac gtgccttatg cgtccttgct tggagtaatg agcccgttgc cacaagaccg
    27901 taataccctt tctacgtacc gtatggtatt cgcctatatt ggcagtttta tagccctgtt
    27961 gctattcatg ccgatggtgc gtttctttag tggaaatagc gatgaattgg cggatcaaca
    28021 acatggatgg accatggctg tcgtagttat cgctatcctg tgcgccattc tcttttatgg
    28081 atgtttcgca tggacaaaag aacgggtaaa accgattaaa gagcaacaag gctcgttaaa
    28141 agatgacttg agagatctat tgcacaacaa gccttggtgg atactattgg gagcaggtgt
    28201 ctccgctctg gttttcaatt ccatccgcga cggggctacc gtatattatt tcaaatactt
    28261 tatcattgag gaagcctatg ccaatgtatc tcttttcgga gtctccttcg tcttaagcgg
    28321 attatatctg gcggtaggac aggcggccaa tattgtcggc gtgatcttgg ccgccccatt
    28381 aagcaaccag atcggaaaga aaagaaccta tatgggctcc atgctgatcg cctcggtttt
    28441 aagcatcctc tttttctggc tcgacaagac ggatctagcc ctgatattca cgttccaagt
    28501 gttcatcagt atttgcgccg gtagtatttt ccccctactt tggtccatgt atgccgattg
    28561 cacggactac tcagaactaa aaacagggaa ccgtgccaca ggattgatct tcagttcctc
    28621 gtccatgagc cagaaattcg gatgggcgat cggcacggct atcacaggct ggctactcgc
    28681 tttcttcggg tttcaggcca ataccgtaca aagcgaggaa acgattagcg gaatcaagat
    28741 gttcctcagt ttcttaccgg ccgtaggtac gatcctgtcc gttgtattta tcgccttcta
    28801 cccgcttagc gagacaaaga tgaaggaaat taccgctacg ttagaaacca aaagaaaaga
    28861 aacaaatgaa taaaatcacc gaagatttac aaaacgaggt tcaatgggag ctagagaaca
    28921 atatcctccc tttctggatg aaccgaatga tagatagtga gtatggtggt ttccatgggc
    28981 aaatcacggg aaacaatcaa cgagtcgtac atgcccctaa aggcgccatc ttgaacgccc
    29041 gtatcctatg gacattctcc gccgcatacc gtttattacg aaagccggaa tatctggaaa
    29101 cggcgacccg tgccaaacgt taccttatcg ataaattcta cgaccaagaa ttcgagggta
    29161 tttactggga attagactat accggtcaac ccgtgcaaac caaaaagcaa atctacgcct
    29221 taggattcgc tatctacgga ttaagcgagt acaaccgggc taccggagat aaagaagcgt
    29281 tggattatgc gatccgtctc ttcaaggcaa tcgaacaata tagtttcgac ccggaaaaga
    29341 acggttatat ggaagccttt acgaaagact ggaaactgat agaggatatg cgactaagcg
    29401 acaaggatga gaatgagaaa aaaactatga acacccatct gcatatcctc gaaccttata
    29461 ctaacttgta tcgggtatgg aaagacgagc acctcaaaaa acaactccga aacttgatcc
    29521 tgattttcac cgacaagatt ctggatcacc gtacctatca tttaaacctc tttttcaacg
    29581 aggattggga aagcaaatac cgtatcatct cctatggtca tgatatagag gcatcttggt
    29641 tactgcatga ggccgctatc gaattgggag acaacgagat tcttcagaaa gtagagccct
    29701 tggttcaaaa ggtagcgata gcggccgaag acgggttatt agcgaacggt agcctcattt
    29761 acgagtatca cccgaatgag aagaaagccg acacggacct gcattggtgg gtgcaagccg
    29821 agaatgtagt gggtcatttc aacttgtatc aacatttcgg agatgagcct gccttaggca
    29881 cagcctatac atgctggaaa ttcattcagc gttatttgat cgacaaggaa caaggggaat
    29941 ggcattggag cgtatcgctc gatcacgaga tcaatcgcga ggatgacaag gccggtttct
    30001 ggaaatgtcc ctatcacaac ggacggatgt gtatggagat tatcgaacga cttgccggcg
    30061 aataaccgtc cggcagaccg cctgccggct cttttttatc agattaacaa ccgtcggaag
    30121 cttccgacat caaaaaaaca agcgatatga acaaattcta ttggatggtg ataggcctcc
    30181 ttctcggttt ggtgaacctc cgggccgaga tcaagctgcc agctttggta agcgacaaca
    30241 tggtactcca acaagccact aaagtacggc tctggggaaa tgcaacccca aattcaagcc
    30301 tgaaagtccg tagttcttgg gacaatacgg aatacacggc ccaagtaaac gatcaaggca
    30361 gatgggaaat ctgggttcag acgccctcgg ccagtttcga aaagcaacag ttaacattaa
    30421 agaatggaca agacaagatt gtcttgcatg atcttctgat cggcgaggta tggttcggtt
    30481 ccggccaatc caatatggaa atgccattaa gaggtttctg gcactgccct atcgagggag
    30541 gaaaccacgc tatcgctaca tccgggaaat ataagaactc gatccgttac gctacgatcc
    30601 aacgggtcgg agccttggaa ccgaaagatt atccggtagg tggcgaatgg aaagtatgtg
    30661 atccgcgaaa cgccccggag ttcggagcta ccgcctattt cttcgcgacc ctattgaccg
    30721 aggtattgaa tgtcccggta ggtatcatca attgtagctg gggcggttcc acggttgaag
    30781 gttggttgcc caaagacatc ctgcggaatt atagcgatat cgatctatcc ttagcgggta
    30841 acgatgagaa aatccatccg atgctacaac ccatgat
//
LOCUS       DBMDTB010000040        30267 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_570_length_30267_cov_12.585494, whole genome shotgun sequence.
ACCESSION   DBMDTB010000040 DBMDTB010000000
VERSION     DBMDTB010000040.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 30267)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 30267)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30267
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_570_length_30267_cov_12.585494"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            234..2048
                     /locus_tag="ACZPB4_08235"
     CDS             234..2048
                     /locus_tag="ACZPB4_08235"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2 protein"
                     /protein_id="HIR1098246.1"
                     /translation="MRKLLLAFCAFATICSAGAQWKPAGDKIKTDWAEKVDPRNVLPE
                     YPRPGMERADWQNLNGEWEYAILPKGQAEPTSFDGNILVPFAVESSLSGVQKEVGEKN
                     ELWYKRTFTVPSSWKGKDILLNFGAVDWKADVFVNDILIGSHTGGFTPFSLNITPYLN
                     GKSTHKLVVRVWDPSDKGYQPRGKQVANPEGIWYTPVTGIWQTVWLEPVASSHITSIK
                     AIPNIDNGVMSVTVGACSDSPVSDIVEVSLLDKGQVVATAKGVQGTELRLAVQNPTLW
                     EPSNPYLYDMKVSLSKNGKKVDEVKSYTAFRKISAERDANGIMRMRLNNKNLFQYGPL
                     DQGWWPDGLYTAPTDEALLYDIVKTKAWGFNMIRKHVKVEPARWYYHCDKEGMLVWQD
                     MPSGDMGNQWAPHTYNGGTDKERTEESIRNYYKEWKEIMDLCVSNPSVVVWVPFNEAW
                     GQFDTEKAAEWTKTYDPSRLVNPASGGNFRACGDILDLHNYPGPAMYLFDPVRVNVLG
                     EYGGIGLAVENHLWWNKRNWGYVQFKNSDEVTAEYVKYAKELKAMVPKGFSAAVYTQT
                     TDVEGEVNGLMTYDRKVIKINEAEVRKANQEVIKALSE"
     gene            2144..2641
                     /locus_tag="ACZPB4_08240"
     CDS             2144..2641
                     /locus_tag="ACZPB4_08240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HIR1098247.1"
                     /translation="MIRNVSLRDAKAIVDIYNEYVVNSVATFETEPLRVEEMEGRIAG
                     ISASYPYLVYVDQDEVVGYCYAHTWKEKAAYKYTLETTVYLSPRYKGKGIGRQLMERL
                     IEECRAGGYHALIACITEGNEASYSLHEKLGFRKVSHFEKVGLKFGRWLDVVDYELII
                     KPNER"
     gene            2708..3313
                     /locus_tag="ACZPB4_08245"
     CDS             2708..3313
                     /locus_tag="ACZPB4_08245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4290 domain-containing protein"
                     /protein_id="HIR1098248.1"
                     /translation="MKYNTEGKRLTLPEYGRNIQNMVDYCVTIQDREERKRCANTIIN
                     IMGNMFPHLRDVNDFKHILWDHLAIMADFKLDIDYPYEIIKKENLYSRPPRIPYNNNR
                     IRYRHYGKTLELMIRKATELQPGMEKDQLVRLLANQMKKSFLTWNKESVDDRKIFKDL
                     DELSGSKIVLSEEEHKLAESRDILARNNSGAHKRNFTRKGR"
     gene            3310..4614
                     /gene="murA"
                     /locus_tag="ACZPB4_08250"
     CDS             3310..4614
                     /gene="murA"
                     /locus_tag="ACZPB4_08250"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005781200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HIR1098249.1"
                     /translation="MSSFVIEGGYRLSGEIVPQGAKNEALEVICATLLTPEKVTIHNV
                     PDILDVNNLIQLLRDMRVKVEHPSADTYTFQADDVDMEYLRTEEFLRKSGSLRGSVMI
                     VGPLVARFGRALIPKPGGDKIGRRRLDTHFVGIQKLGACFSYDAERQVYEIEARQLKG
                     AYMLLDEASVTGTANILMAAVLAEGVTTIYNAACEPYLQQLSTMLNRMGARISGVGSN
                     LLTIEGVRSLSGTEHTILPDMIEVGSFIGMAAMTGSEITIKNTGYDKLGIIPDAFRRL
                     GITVEQRGDDIYIPRHDSYEIDTFIDGSIMTIADAPWPGLTPDLLSVFLVVATQSVGS
                     VLIHQKMFESRLFFVDKLIDMGAQIILCDPHRATVIGLGNRFKLRGSTMVSPDIRAGI
                     ALLIAAMSAEGTSTIHNIDQIDRGYQGIDKRLNRIGARITRI"
     gene            4627..5148
                     /gene="rimM"
                     /locus_tag="ACZPB4_08255"
     CDS             4627..5148
                     /gene="rimM"
                     /locus_tag="ACZPB4_08255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780929.1"
                     /note="Essential for efficient processing of 16S rRNA;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HIR1098250.1"
                     /translation="MIREEEVFKIGQFAKPHGIKGELSLVTNSDVLEDAEDPYIVCEM
                     DGILVPFFVEDFRYKTDTVVLVKLEDVNSEEDARMFVGKEVFYPLDAVDEEDLVGDMT
                     WDSFIGYTVTDVQKGYLGEITDVDETTINVLLRVDHKGEELLIPAVEELITEADHEAR
                     SLTVSLPEGLIDL"
     gene            5177..6040
                     /locus_tag="ACZPB4_08260"
     CDS             5177..6040
                     /locus_tag="ACZPB4_08260"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M23 family metallopeptidase"
                     /protein_id="HIR1098251.1"
                     /translation="MKKKNTKSFWHRIRFKYKLSFINEGTLEEVWSFRLSQLSAFVTL
                     AVFAFFLIAVTAFIIIKTPIRNYLPGYLDVEVRKEIMQNALRADSLERMIEIQSLYLD
                     NVAGIISGTMPLDSIRQIDSLASNDINYEIPRSKEETRFVKDYEEEEKYNLSVLTDPG
                     KVPTEGVFFYKPVNGVVTSHYETDVHHYGVDLAAAPKESVLATLDGTVIYTGFDPNHG
                     NVIQLQHKNGFISVYKHNELLLKEVGDHVVAGEAIALVGNTGELSTGPHLHFELWYKG
                     NPVNPEEYIAF"
     gene            6047..7198
                     /locus_tag="ACZPB4_08265"
     CDS             6047..7198
                     /locus_tag="ACZPB4_08265"
                     /EC_number="1.1.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0030604 - 1-deoxy-D-xylulose-5-phosphate
                     reductoisomerase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070402 - NADPH binding [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate reductoisomerase"
                     /protein_id="HIR1098252.1"
                     /translation="MKKRQLAILGSTGSIGTQALEVVSEHSDLFEVYALTANNQVDLL
                     INQARKYMPEVVVIANERKYPELKEALEDLPIKVWAGADAIAQMVQSEPIDMVLTAMV
                     GYSGLRPTISAIKAGKAIALANKETLVVAGELIMKLAAEHKVPILPVDSEHSAIFQCL
                     TGAYDNPIEKILLTASGGPFRRKTLEELATVTKAQALRHPNWTMGAKITIDSASMMNK
                     GFEMIEAKWLFDVTPDQVQVVVHPQSVIHSMVQFEDGAVIAQLGIPDMKLPIAYAFSF
                     PTRMRSMAPRLDFNQYSTLTFEEPDMERFRNLAFAFEAARQGGNMPCILNAANEVVVA
                     AFLQDRIGFLQMSDVIERTMRKASFIVNPSYEDYVATDTEARRLAAELF"
     gene            7229..8557
                     /gene="rseP"
                     /locus_tag="ACZPB4_08270"
     CDS             7229..8557
                     /gene="rseP"
                     /locus_tag="ACZPB4_08270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008771690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HIR1098253.1"
                     /translation="METFLIKALQLILSLSILVIVHEFGHFIFARIFKVRVEKFYLFF
                     DPWFSLFKYKPKNSDTEYGVGWLPLGGYCKISGMIDESMDKEAMAQPPKPYEFRSKPA
                     GQRLMIMVAGVVFNFLLALFIYSMILFTWGDTYLPLKNMKMGMNYSETFQNVGFQDGD
                     ILLRADNEELERFGSDSFRKVVEAKTVTVLRDGRETVISIPEDMMQRCMRDGKGFADP
                     LRIPMVVRELPDKNAPAALAGMQPKDSVVAINGVATPTFYDASGLLSENKGEEVTVDF
                     YRNGQLESLTMRTDSAGKIGVAVMLPTDLYQTVTRKYGFFESFPAGIKLGINTLKGYV
                     NDMKYVFTKEGASSLGGFGTIGGLFPSVWDWRIFWERTAFLSIILAFMNILPIPALDG
                     GHVMFLIYEVVARRKPSDKFLEYAQMAGMFILFALLIYANGNDIFRFFFK"
     gene            complement(8649..9392)
                     /locus_tag="ACZPB4_08275"
     CDS             complement(8649..9392)
                     /locus_tag="ACZPB4_08275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HIR1098254.1"
                     /translation="MKKIVLLVALCLCVGNLFAQDADKLRDEGDAALKAKDYATVVTK
                     YGEYLKQNNYQDTARIFNCGYAANQAKNYAEAAKYFDMAVKMNYNVDDSYVGEAMAYR
                     NLNKTEEFLTTVKEGLKVIPDGNKNKTNLEKLLYGYCIKQGQAAQKKGDLAGAEKMYK
                     EVLAVSNKDYQSNAYYSLGAMLYGNGAKILQAATPIATSEPDKYNAEKAKADKDFKQA
                     KEYLTKAVELDPKDENSKKILASINDILK"
     gene            complement(9548..10642)
                     /gene="ald"
                     /locus_tag="ACZPB4_08280"
     CDS             complement(9548..10642)
                     /gene="ald"
                     /locus_tag="ACZPB4_08280"
                     /EC_number="1.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000286 - alanine dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0042853 - L-alanine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
                     /protein_id="HIR1098255.1"
                     /translation="MIIGIPKEIKNNENRVALTPAGAKELVKRGHTVYVQHTAGINSG
                     FADDAYVAAGARILPSIEDVYGIAEMIVKVKEPIASEYPLVRKGQLVFTYFHFASDEA
                     LTLAMIKSGSICLAYETVENPDHTLPLLIPMSEVAGRMSVQEGARFLEKPQGGKGVLL
                     GGVPGVKPGKVLVLGGGVVGHNAALMAAGLGADVTIADISLPRLRYLSETMPKNVKTL
                     FSSTHTIEQELPTTDLVIGAVLIPGAKAPHLITRDMLKLLKPGSVLVDVAIDQGGCFE
                     TSHPTTHANPVYEIDDILHYCVANIPGAVPQTSTLALTNATLPYVIKLADRGWEKACE
                     EDPGLELGLNIVEGKIVYPAVAEAFPSLKA"
     gene            complement(10739..14119)
                     /gene="secA"
                     /locus_tag="ACZPB4_08285"
     CDS             complement(10739..14119)
                     /gene="secA"
                     /locus_tag="ACZPB4_08285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006605 - protein targeting [Evidence IEA];
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HIR1098256.1"
                     /translation="MGFNEFMTKLFGNKSQRDLKEITPYVDKVKAVYPSIKALSNDEL
                     RAKTDEIKQRIQDYVAEEKAQVEELRKGIEDKELEEREAIWAEVDKIEKAITDKMEVV
                     LEQSLPEVFAIMKDTARRFAENEEVVVTANQFDRDLAARFDFVRIEDDKAIYANHWKA
                     GGNEITWDMIHYDVQLFGGVVLHKGKIAEMATGEGKTLVATLPVFLNALTRNGVHVVT
                     VNDYLSKRDSEWMGPLYMFHGLSVDCIDKHQPNSEARRKAYEADITFGTNNEFGFDYL
                     RDNMAISPKDLVQRKHNYSIVDEVDSVLIDDARTPLIISGPIPRGEEQLFEQFRPNVE
                     VVVNAQKDLCSKLLIEAKKKMASDDQKVVEEGSILLYRSFKGYPRNKALIKFLSEQGV
                     KAQMLKTEEYFMSENMRHMHEATDELYFVIDEKNNSIELTDKGIDLLTGKTDDPTFFV
                     LPDITSQLSQLENMTGTEEEKQAQKDEILANYSVKSERVHTINQLLKAYTLFEKDDEY
                     VVMDNKVMIVDEQTGRIMDGRRYSDGLHQAIEAKERVKVEAATQTFATITLQNYFRMY
                     HKLSGMTGTAETEAGEFWDIYKLDVVVIPTNRPIARNDMNDRIYKTKREKYNAVIEEI
                     VQLTEAGRPVLVGTTSVEISELLSRMLTMRKIQHNVLNAKLHQKEAEIVALAGQKSTV
                     TIATNMAGRGTDIKLSKDVKDAGGLAIIGTERHESRRVDRQLRGRAGRQGDPGSSVFF
                     VSLEDDLMRLFASEKIAGLMDKLGFKEGEVLEHNMLSKSVERAQKKVEENNFGIRKRL
                     LEYDDVMNSQRNVIYTRRRHALMGERIGLDVLNTIYDTSTAIADQHAEDFEGFKLELF
                     KTFAMESPFTEDEFKSMKPEQLVEKLFEEALKTYKRRMERMTQVAHPVIKQVYENQGA
                     MYENIMIPITDGKRMYNVSCNLKEAYDTECKAIVKSFQKSIVLHMIDEGWKEHLREMD
                     ELRHSVQNASYENKDPLLIYKLESYNLFKTMVDNMNRKTAAILMRGQIPVREEPTEEQ
                     RQAMQARQAAVAQQAAQAIAEERARQRIAVQEAAPEKHEDMSRYRTEKTDLSGNNTQA
                     EAPQPKQAPVRAEKRVGRNDPCPCGSGKKYKNCHGQGL"
     gene            complement(14252..15838)
                     /locus_tag="ACZPB4_08290"
     CDS             complement(14252..15838)
                     /locus_tag="ACZPB4_08290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HIR1098257.1"
                     /translation="MRKIITSLIAILVVTNLEAQQRTPKLVVCITVDQLRGDYIEYFY
                     NTFGERGFKRLMNEGLVYNNIRFEFSDIDQASAFATLFTGSNPCFSGIAGDKTFDFEK
                     EKEVSILNDPEYLGNYTKENYSPKNLFSSTIGDELKIASQGRSDVYSIAPDAESAILS
                     AGHAANGAFWMDNTNGKWATTTYYKGIPWYVDRYNNGPESLASRLETMVWTPTLPMEK
                     YNAFPYVLDDLPFRYTFSEKFANCYPNLKTSPFINKEINRLALQFLEYGGFGTRSCPD
                     MLSITYYAGNYRGTMSKEYTREIQDTYYQLDQDIEKLLDTIDKKVGLANTLVVFTGSG
                     YYKSEESYPDGLMVNGGEFHPKRCLALLNMYLMAIYGQHTSWVQGYYDNQIYLNRKAI
                     EDAKLDLTTLQNKAAEFIQEFSGVQLVTTGRSLLTGDWNEGTAKFRQGTHHLRRGDLI
                     IELQPGWKVNLDNPKEKVKIIRNNAVITPLVFMGNGLKPQHIYREVKATEVAPTVTHV
                     LRIRPPNATQSLPLWELTTK"
     gene            complement(15835..17022)
                     /locus_tag="ACZPB4_08295"
     CDS             complement(15835..17022)
                     /locus_tag="ACZPB4_08295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein N-acyltransferase Lnb
                     domain-containing protein"
                     /protein_id="HIR1098258.1"
                     /translation="MTKSIFLFLLGILSLSAIAQPKLSEEARISLMTSAPYDEEVFTV
                     YGHAALRIYDPKQNIDYIFNYGIFDFSKPNFIYRFAKGETDYKLGVADFQDYVIEYQM
                     RGSDITEQVLNLTQEEKEHIWDALLINYRPENRVYRYNFFFDNCATRPAAILEKEING
                     SVDYQYPYQSQTFRDLINYCTRNHPWLTFGCDLALGSPTDREATQHEMLFLPPYLKEA
                     FSKATITSPDGTIRPLVSETHVIGAGEADEPEKDIWDLFTPLVCAWLLFGIVLGLTWI
                     EWRKKKYFLWVDCVLFSVAGAGGVILFFLSFISVHPCTWPNWSLVWLQPLDLIAVILF
                     CVKKLKKAAYYYHFINFAALTLMLLGWHFIPQHLNSAFIPLVASIWVRSGWGVYRKIW
                     RIG"
     gene            complement(17386..17458)
                     /locus_tag="ACZPB4_08300"
     tRNA            complement(17386..17458)
                     /locus_tag="ACZPB4_08300"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(17423..17425),aa:Gly,seq:ccc)
     gene            17536..18303
                     /gene="argB"
                     /locus_tag="ACZPB4_08305"
     CDS             17536..18303
                     /gene="argB"
                     /locus_tag="ACZPB4_08305"
                     /EC_number="2.7.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003991 - acetylglutamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006592 - ornithine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetylglutamate kinase"
                     /protein_id="HIR1098259.1"
                     /translation="MEKLVLIKVGGKIVEEEETLRQLLNDFAAIEGYKVLVHGGGRSA
                     TKLAAQLGIESKMVNGRRITDAETLKVVTMVYGGLVNKNIVAGLQALGVNALGLTGAD
                     MNLMRSDKRPVAEVDYGFVGDVKEVNADLLASLIHQGIVPVLAPLTHDKQGHMLNTNA
                     DTIAGEAAKALAKHFEVTLMFCFEKKGVLLDENDDESVIPEIDRIAFKGYVEQGIIQG
                     GMIPKLENAYQAIDAGVKQVIITQASEIHQGKGTRVF"
     gene            complement(18352..19020)
                     /locus_tag="ACZPB4_08310"
     CDS             complement(18352..19020)
                     /locus_tag="ACZPB4_08310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008771694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-disaccharide hydrolase"
                     /protein_id="HIR1098260.1"
                     /translation="MKHFLLAMATLWCVASTFSSFAADNNKWKPLFGKNLENANYNPE
                     VWSETDGVLGAVKDESIWTKDEYENFELDLDFKTDVGTNSGVVVYCTDTKDWIPNSVE
                     IQIADDHCEKWGNGKPYEKCGAIYGHLGAVQDKVVKKPGEWNHMRIKCAGQHIMVILN
                     GKKVTEMDMSKWTSGTKNPDGSDIPSWLPKPFAELPTKGFIGLQGKHGDSLIWFRNIK
                     IRSL"
     gene            19583..22828
                     /locus_tag="ACZPB4_08315"
     CDS             19583..22828
                     /locus_tag="ACZPB4_08315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SusC/RagA family TonB-linked outer membrane
                     protein"
                     /protein_id="HIR1098261.1"
                     /translation="MRRLTFLLLCLFIGIGVATAQTMKITGNVISSEDQQPVIGAAVV
                     VKGTTIGTVTDFEGNFSLDVPRDAKMIFISYVGLKTKEVPVASVINVVLDSDSKALDE
                     VVVTAMGLTREKKALGYALQEVKSDELTKAGQQSLATSLSGKIAGVQITSQGGQVGAS
                     QNIVVRGNSSFGNNQPLIVVDGVPIANDNAKGATVNLGSGLNDINPEDIESISVLKGG
                     SAALYGMRAGNGVILVTTKSGKKDKGVSISYEGDITIDRVYNLPRLQNKYGQGYYASE
                     YDWKEAQAGGYSGDYQTFALENGYNYVDGMGSGINDNADESWGPRLDIGLNLPQYNSP
                     VIDGVRQATPWVSCPDNIKNFFQTGYSMNHTVALSASTDKTSTRASLSFRDQSGTTPN
                     TDQKRYAMAVNTKMTFNKYIDFDLSANYIRTKSANLPGTGYNSTNALQSIMQWFGRQV
                     DLKDLKNNWDQVDEYGKYTHYNWIQSFHANPYWTLNKNTNSYDRNRFYGKTSLYIKPT
                     DWLKFEGRMGLDHYDSNQFSRILWNIDYPNGYFRSFDRSMTEFNADFIAYVNKNFGDW
                     ALNGLAGANYRDYQTAIMGTGADELTAEGLFTVANAHGTPYTLNDHEKRRSNSVYANA
                     SIGYKNMAYAEVSVRNDWDSTIKDAFFYPSFSGSWILTETFPGLQNGDYLNFLKLRGG
                     WAKIGSATDPYRSNAYYSLISSSFNGTTLFYNPTILPPTNLRPESVKTWEVGVEANLF
                     NNRLHIDAAYYNKVTSDQIMNANVATSTGYTSMYINAGKISNKGVELQVSGDIIKNPK
                     GFNWTATLNWAKDKSRIDELYTDPVTGQSLDAYQIGSSWSVKNYAMVGKSWGTLVGTG
                     YVYNEDGSILVEDGIPVYEAGKEIGDVTPKWLAGFSNEFSYKDWSFGFLLDFRLGGDI
                     YSVTQAFGSQTGILKHTAEGDLRENGVVLGQNYMTDKVFKTADGKINDVAVNAEDFFY
                     NYYTICEMSVFDGSYLKLREAHLTYNFPKSILEKTKCIKAAHVSLVGTNLALLWVHKS
                     NIAHIDPESTSTGGDDPETAATSRGFNSGVGFESNSYPPSRSFGLKLGVTF"
     gene            22854..24341
                     /locus_tag="ACZPB4_08320"
     CDS             22854..24341
                     /locus_tag="ACZPB4_08320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SusD/RagB family nutrient-binding outer membrane
                     lipoprotein"
                     /protein_id="HIR1098262.1"
                     /translation="MKRYIKNFMMAMMVGATVFGSSCTDSFEEVNTDPDSPTDVPTTN
                     LLAYSLYYTSYRLYDRWFAMDEPMTFCGYASKMTYIDESRYNFRTGVQDTNWEYLYRI
                     LNNLKDIEKRATFNETPNMLNVSKVMQVHLMQVATDRWRDVPYTDAAKMTDGILQPKY
                     DKQEDIYPGLLATLKEAADGFADGGSDDLGEGDLLFGGDIEKWQRYCNSMRLRLAMRI
                     SEVSPALAKETVEEVMGNPTKYPIMESNDDNAFFWWIGTDPNYYEPMADGYRTRKTEY
                     CAADVIVDHMNTREDPRRSSYFQPTKESVEAGEPKYVGYTIGAKANAVASKYSIWGAR
                     FFTDLAGFSPYMRVAEPWFCVAEASMLGWNTGISAEDAYNKAVTYSMEENSVSAEDIA
                     DYLANAGKFTNDKKQIYYEEWVAMFKQGMEGWSLYRRTGVPDNLYPAPGRPANYSNHN
                     VPPFRSPYPDKERNLNNANCAPFDAEVVDNLWGKQMWWDTRTGVH"
     gene            24478..25950
                     /locus_tag="ACZPB4_08325"
     CDS             24478..25950
                     /locus_tag="ACZPB4_08325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010184676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HIR1098263.1"
                     /translation="MEKEGMMVVDIKNIVTRLPELRFTAPVNWRIDEGQQWAVIGPNG
                     AGKTLIADIMQRKFAFKEGEVVFSGDGKVSDFIKSIAFKDIYSLADCRNSYYQQRWHS
                     TETEEMPIVEELLKEYAGSDNLAKILTLFGIEDLLPKRLIFLSSGELRKFLIVRTLLS
                     RPRVLILDNPFIGLDAPSRDLLVEMLGQMTKLNGVQVVLLLSNPNDIPAMITHVLPIH
                     DRTCLPPLTREEFMSDTELIARLFPTEGIHACEEVGKVRLPVDMNKIASLHEVTLRME
                     HVKIRYGSRTILKDLDWEIKNGEKWALFGPNGAGKSTLLSLVYADNPQSYANTLYLFD
                     RKRGSGESIWDIKKRIGYVSPEMHLYYKENVPTLNIVGSGFFDSIGLFRKCNAEQETV
                     ALEWMKVFGIEHLKDRLFLTLSSGEQRLALLARAFVKDPDLIILDEPLHGLDVSNKKK
                     AAAIIEQFCDRPGKTLIYVTHYPHELPACVDKRFELVKHS"
     gene            complement(26028..27398)
                     /locus_tag="ACZPB4_08330"
     CDS             complement(26028..27398)
                     /locus_tag="ACZPB4_08330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RagB/SusD family nutrient uptake outer membrane
                     protein"
                     /protein_id="HIR1098264.1"
                     /translation="MKKIYLVGLAFALLTASCDDVLEKTSSTQLPTIDAISSVADLTN
                     AVNGVYEQQATEVGSYGAEFTLLADLRSGDFQSISTVNHAGPMYRYQTGKNDEMVYSF
                     YKLFYNSLARLNNVLAAAENLEGADVDILKGELYAMRALYHFDLARVFAKLPSTTDMN
                     DLGIVLSTEVYPTDYIGTRATLQQTYDQILKDIETALPLLSKDKQTGHINYWGALAIR
                     ARAYLYLEKNKEALADCKEIIASSPYKLYTRDEYIGAWDKEGTNEAIFEILVTPNYNA
                     QRNSIGYFTHASGYGECAATESFLEELAKHPGDIRTELFAKETDNGYDGTYPQKYKGR
                     DGQIYVNNPKVVRLSEVYLIAAEAALKAGDTSAAAGYMNTLRKNRIENYTDVASITLD
                     DILLERRLELFTEGHTAWDAWRNGKSVNNKFVGEVKPGDYRTIMAIPIGEITVSRGQL
                     IQNPGY"
     gene            complement(27419..30253)
                     /locus_tag="ACZPB4_08335"
     CDS             complement(27419..30253)
                     /locus_tag="ACZPB4_08335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016278647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SusC/RagA family TonB-linked outer membrane
                     protein"
                     /protein_id="HIR1098265.1"
                     /translation="MVFSYVGMVAKEAPIQDVMKVVLNTAATELDEVMVVAYGTAKKS
                     SFTGSAKAVNAEDIVAGSKESLDKALSGKMSGVRVTSNTGDPGAPGDINIRGVGSISA
                     AKSPLYVVDGVPVKSDSDMAYYGKQSSLLSSLNPDDIESMTVLKDAAAASLYGSRAAN
                     GVIIITTKAGKRGKTKVSYNGEVGWSNMAVKQYETMNASELLLYGKEAISNYYILNGL
                     AGNRDQAYALIDKEGDMEAFFNDPSGNTDTNWRDEVYRTALTHNHQLSVNGGNDRTQF
                     YVGLGYNNAEGIVIGSDFERFSGRINLDHQVNNWLTIGVKQMIAFTTQNGFRDQQNQD
                     QGIGTASPLSLVYSSDPTAPVKNPDGTYNADSNWGAASNPHLMLGKEQWIKSRVMRSM
                     SNIDLGVKFSKQLSFKTIFGYDYIDTKHFEYWSPNSVDGKAVGGLGSRYTYENRNLTS
                     SSTLRYANTWNDVHNFDILGGFEVTEDELTAIYTTAKQYSTDKLPELGNGQPDGASSE
                     VFGSGIVSYLATGNYNYDNKYYLSASFRRDGSSRLGTDNRWANFWSVSGAWRISGENF
                     LKDNELFSDLKVRFSYGTNGNLPGSYYANQALYAFSGGYGPSSAIYWNQAGNEELGWE
                     KSKNMNVGFDWNLFNRVNLTVEYYNKTTTDLLFEIPTSIVTGFEKNWQNLGKLRNSGI
                     EIEVNSQNIKNQHFSWDTNFNLTFQKATIKELPNHNDIEYGDGDMYLHREGESMYTFY
                     LPEWKGVNPDTGLGEFWKDPNDHSKGVVNKYDEAEKGIVGKAIPDVTGGLTNTFRLYD
                     FDLSFLITYQFGGDIFDYPNYFFHHDGFRLGSFNLEKSVAGNYWMNPGDNALYPKPIY
                     QNPYRSDRFSSRTIVSSDNIRMREITLGYNVPVLKNIFSNLRVYFRANNPFMIWAKTK
                     GIDPDVPLNGYRQVDTPVSKSFVFGVNITL"
BASE COUNT         7530 a         6613 c         7710 g         8414 t
ORIGIN      
        1 attcacgtac gtgtttttcc ggaaatgata ttgatgtaaa ataggaacat taaaaaaaga
       61 caataacctt accttgtgag attctgtcac aagagatatt ccgggtattt gatggttaga
      121 tcgatttggg tacggttctc ctattggtat ccgaggacga tgtggatttt ggatattttc
      181 tattatcttt gtcacttgaa agtgtattat caattcaaaa tgtaaataat atcatgagaa
      241 aattattgtt agccttttgt gcgttcgcaa cgatttgtag cgccggggcg cagtggaagc
      301 ccgccggaga caagatcaag acggactggg ctgagaaagt agatccccgg aatgtattgc
      361 cagaatatcc acgccccggg atggaacgtg cggattggca gaatttgaac ggcgagtggg
      421 aatacgctat ccttccaaaa ggacaggcag agccgacgag tttcgatggg aatatcttgg
      481 tgccgttcgc cgtggaatcc tccttgtccg gtgtgcaaaa agaagtgggg gagaagaatg
      541 agttgtggta taaacgaacc tttacggtgc cctcctcatg gaaaggaaaa gatatcttgt
      601 tgaacttcgg cgccgtggat tggaaagcgg acgtgttcgt gaatgatatc ctgatcggtt
      661 cccacacggg aggctttacc ccgttttcct tgaatatcac tccctatctg aatggcaaaa
      721 gtacgcataa gctggtggtg cgtgtatggg acccgagcga taaaggctac caaccccgtg
      781 gaaagcaagt ggccaacccg gagggaatct ggtatacgcc ggtcaccgga atctggcaga
      841 ccgtatggct ggagccggtc gcttcctcgc atatcacctc tatcaaggcg atcccgaata
      901 tcgataatgg cgtgatgagc gtgacggtcg gggcttgttc cgactccccg gtgtcggaca
      961 tcgtggaggt cagcttgctc gataaggggc aggtggttgc taccgccaag ggcgtacaag
     1021 ggacagaatt acgcttggcc gtgcaaaatc ctacgttgtg ggaaccttcc aatccttatt
     1081 tatatgatat gaaggtgagc ttgtcgaaga atggcaagaa ggtggacgag gtgaaatcgt
     1141 acaccgcctt ccgtaagata tccgccgagc gtgacgccaa cggcatcatg cgtatgcgct
     1201 tgaacaacaa gaacctgttc caatacggcc cgctggatca aggctggtgg cccgacgggc
     1261 tttacacggc tcccacggac gaggcgttgc tgtatgatat cgtgaagacg aaagcgtggg
     1321 gcttcaacat gatccgcaag cacgtgaagg tagagccggc ccgctggtac tatcattgcg
     1381 ataaggaagg tatgctggtt tggcaggata tgcctagcgg cgacatgggt aaccaatggg
     1441 cgcctcatac gtataacggt ggaaccgaca aggagcgtac cgaggagtct atccgtaatt
     1501 attacaagga gtggaaggag atcatggacc tgtgcgtctc gaatcctagc gtagtagtat
     1561 gggtgccctt caacgaggct tggggccagt tcgataccga gaaggctgcc gagtggacaa
     1621 aaacatacga tccttcccgt ctggtgaatc cggccagtgg cggtaatttc cgtgcgtgcg
     1681 gcgatatctt ggatttgcat aattacccgg gcccggcgat gtacctgttc gatccggtgc
     1741 gtgtaaacgt attgggcgag tatggtggta tcggcttggc cgtggagaac catttgtggt
     1801 ggaataaacg caactggggc tatgtacagt ttaagaatag cgatgaggtg accgccgagt
     1861 acgtgaagta cgccaaggag ttgaaggcga tggtcccgaa gggtttctcc gccgctgtct
     1921 acacgcaaac cacggacgtg gaaggcgagg tgaacggcct tatgacctac gaccgtaaag
     1981 tgatcaagat caacgaggcc gaggtgcgca aggcgaacca agaggtgatc aaggccttgt
     2041 ctgagtagaa ggcttagaaa aaatagttat ttgactcgat gatagatccg gtccgggcaa
     2101 agagagattc tttcccggat cggattgttt tagcgaaatg aatatgattc ggaatgtgag
     2161 tttgcgagac gccaaggcga tcgtggatat atacaatgaa tatgtcgtga atagcgtggc
     2221 tacgtttgag acggaacctt tgcgggtgga ggagatggag ggtcgcatag ccgggatctc
     2281 ggcgagctat ccttatctgg tgtacgtgga tcaggatgag gtcgtgggat attgctatgc
     2341 ccatacgtgg aaagaaaagg cagcttataa atatacgctt gagaccaccg tttatttatc
     2401 cccgagatac aagggcaagg ggatcggccg gcagcttatg gaaaggctga tcgaggaatg
     2461 tcgggcaggc ggctaccacg ccctgatcgc ctgcatcact gaggggaatg aggccagcta
     2521 ctcgctgcat gagaagctgg ggttcagaaa agtatcccac ttcgagaaag tagggctgaa
     2581 attcgggcgg tggctggacg tggtagatta tgaattgata attaagccta acgagaggta
     2641 actttcgaat ctcaattttc aattctcaat taatatacct atcttcgcga taaacaaaat
     2701 gtaaagaatg aaatacaata cagaaggaaa aagattgact ttgcccgaat acggacgcaa
     2761 tatccaaaat atggtggact attgcgtgac tatccaagac agggaagagc gtaagcgttg
     2821 cgccaacacg attatcaaca tcatgggaaa catgttcccg cacttgcgtg acgtaaacga
     2881 ctttaagcat atcctttggg atcatctggc gatcatggcc gattttaagc tcgatataga
     2941 ctatccgtac gagatcatca agaaggagaa cctgtatagc cgtccgcctc gtatcccgta
     3001 caacaataac cgtatacgct accgccatta cggaaagacc ttggagctga tgatccgcaa
     3061 ggccacggag ctgcaacccg gcatggagaa agaccagctc gtgcgactgc tggccaacca
     3121 gatgaagaaa tcgttcctta cttggaacaa ggaaagcgtg gacgaccgta agatcttcaa
     3181 ggatctggac gaactctccg gcagcaagat cgtattgagc gaggaggaac ataaactggc
     3241 cgagagccgt gatatattgg cccgtaataa cagtggcgcc cacaaaagaa actttacgcg
     3301 taaaggcaga tgagctcgtt cgttatagaa ggtggttatc gcttgtccgg cgagatcgtc
     3361 ccgcaaggcg ccaagaatga ggcgctggag gtgatctgtg cgacattgct aacaccggag
     3421 aaggtgacca tacacaatgt gcccgatatc ttggacgtga ataacttaat ccagctcctt
     3481 agggatatga gggtcaaggt ggagcatccg tccgccgata cctatacctt tcaggcggac
     3541 gacgtggaca tggagtattt acgtaccgag gagttcctgc gcaagagtgg tagcctgcgg
     3601 ggttccgtga tgatcgtagg cccgttggta gcccgcttcg gcagggcgct gatcccgaaa
     3661 ccgggtggcg acaagatcgg gcgacgccgg ctggatacgc acttcgtggg aatccagaag
     3721 ctgggcgctt gctttagcta cgacgccgag cggcaagtat acgagataga ggcacgccag
     3781 ttgaaaggcg cttatatgct gctcgacgag gcttccgtga ccggaacggc gaatatcttg
     3841 atggctgccg tgctggccga gggggtgacg acgatctata acgccgcctg cgagccttac
     3901 ctgcaacaac tttccacgat gctgaaccgc atgggagcga gaatctcagg tgtcggttct
     3961 aacctattga caatagaagg tgtacggtcg ctttccggca cggagcatac catcctcccc
     4021 gatatgatcg aggtgggtag ctttatcggt atggccgcta tgaccggatc ggagatcacc
     4081 atcaagaata caggatatga taagctgggg atcatcccgg acgcttttcg ccgcttgggt
     4141 attaccgtgg agcagcgagg cgatgatatt tatatccccc ggcatgattc ctacgagatc
     4201 gatacgttta tcgatggttc tatcatgacc atcgccgacg ctccttggcc ggggcttaca
     4261 ccggacttgc tgagcgtatt tctcgtagtg gctacgcaat ccgtgggaag cgtgctgatc
     4321 caccagaaaa tgtttgagag ccgcttgttc tttgtggaca agctaatcga tatgggagcc
     4381 cagatcatcc tttgcgaccc gcaccgggct acggtgatcg ggctgggcaa ccgcttcaag
     4441 ttacggggct ctacgatggt atccccggat atccgtgcgg gtatcgcctt gctgatcgcc
     4501 gccatgagcg ccgagggcac cagcacgatc cataatatag accagatcga ccggggatat
     4561 caagggatcg ataagcgatt gaaccggatc ggggcacgta tcacgaggat ttaaagattt
     4621 taggcgatga ttagagaaga agaggttttc aagatcgggc agtttgccaa gccccatggc
     4681 atcaaggggg agttgtcgtt ggtgacgaat agcgatgtgc tggaagatgc cgaggacccg
     4741 tacattgttt gcgagatgga tggtatcttg gtaccgttct tcgtggagga tttccgctat
     4801 aagaccgata cggtggtctt ggtgaaactg gaggacgtga attccgagga ggatgctcgt
     4861 atgtttgtgg gcaaggaggt gttttatcct ttggacgccg tggacgagga ggatctcgtg
     4921 ggggatatga cgtgggacag ttttatcggt tataccgtga cggacgtaca gaaaggctat
     4981 ttaggagaga taacagacgt ggatgagacg acaatcaacg tccttctgcg tgtcgatcat
     5041 aaaggcgagg agctgttgat cccagccgtg gaggagttga tcaccgaggc cgaccatgag
     5101 gcccgtagcc tcactgtgtc tttgccggag ggactgattg atttataatt gagaatttat
     5161 aattgaagat taggggttga aaaagaagaa tacgaaatcg ttttggcacc ggatccggtt
     5221 taaatataaa ctttccttca tcaatgaggg gacgttggag gaggtgtggt ctttccggct
     5281 ttcgcagtta tcggcgtttg tcactttggc ggtgttcgcc tttttcttga tcgccgttac
     5341 cgcttttatc atcatcaaga caccgattcg caactacttg ccgggttatc tcgacgtgga
     5401 ggttcgcaag gagattatgc agaatgcctt gcgggcggat tcgttggagc gtatgatcga
     5461 gatccagtcc ctttatctgg ataacgtggc cggaatcatt tccggtacga tgcccttgga
     5521 ctcgatccgc cagatagatt ctttggctag caacgatatt aactatgaga ttcctcgtag
     5581 taaggaagag actcgcttcg tgaaagatta cgaggaagag gagaaatata atttatcggt
     5641 attgaccgac ccgggcaagg tcccgaccga gggggtcttt ttctataagc ccgtgaatgg
     5701 cgtggtcacc tctcattatg agacggatgt ccatcattat ggcgtggatc tggccgcggc
     5761 cccgaaggag agtgtcttgg ctacgttgga tggtacggtg atctataccg gtttcgatcc
     5821 gaaccacgga aacgtaattc aattacaaca taagaacgga ttcatctcgg tttataagca
     5881 caacgaattg ttgctaaaag aggtgggaga ccatgtggta gccggtgagg cgatcgcttt
     5941 ggtcgggaat acgggagagt tgtctaccgg gccgcacctg catttcgagt tgtggtataa
     6001 gggcaatcct gtgaatccgg aagaatatat agctttttga tattccatga aaaaaagaca
     6061 gttagcgata ttaggctcga ccggttccat cggaacccaa gccttggagg tagtgagcga
     6121 gcattccgat cttttcgagg tgtatgcctt gaccgcgaat aaccaagtgg acttattgat
     6181 caatcaggcc cggaaatata tgccggaggt ggtggtgatc gccaacgagc ggaaatatcc
     6241 cgagctgaaa gaggccttgg aggacttgcc gatcaaggta tgggcgggtg ccgacgctat
     6301 cgcccagatg gtgcagtcgg agccgatcga tatggtgctg acggcgatgg tgggttattc
     6361 cggcttgcga ccgacgatct cggcgatcaa ggcgggaaag gcgatcgcct tggcgaataa
     6421 ggaaactttg gtcgtggccg gcgagctgat catgaagctg gccgccgagc ataaggtgcc
     6481 tatcttgccg gtggactcgg aacattcggc catttttcaa tgtttaacag gtgcgtacga
     6541 taatccgatc gagaagatct tgctgacggc ttccggcggt ccgttccggc ggaagacgct
     6601 ggaggagctg gctaccgtga cgaaggcgca ggccttgagg catccgaact ggacgatggg
     6661 ggcgaagatc acgatagact cggcctcgat gatgaacaag ggcttcgaga tgatcgaggc
     6721 gaaatggttg ttcgatgtca cgccggatca ggtacaggtg gtggtgcacc cacagtcggt
     6781 gatccactcg atggtgcagt ttgaggatgg cgccgtgatc gcccagctgg gaattcccga
     6841 catgaaattg ccgatcgcct acgctttctc gtttccgaca cgtatgagga gcatggcgcc
     6901 ccgtctggat tttaaccaat attcgacttt gacgttcgag gagccggata tggaacgttt
     6961 ccgcaacttg gctttcgctt tcgaggcggc ccgccaagga gggaatatgc cctgtatctt
     7021 gaatgccgcc aatgaggtgg tggtggctgc cttcctgcaa gatcgtatcg gcttcttgca
     7081 aatgagcgac gtgatcgagc ggactatgcg gaaagcctcg tttatcgtca atccctcgta
     7141 tgaggattac gtggctaccg acaccgaggc taggcggttg gcggccgagt tattttgaaa
     7201 taatttaaaa cagaacaaac aatagtagat ggaaactttt ttgattaagg cgttacagct
     7261 catcttgagc ttatcgatac tggtgattgt ccacgagttc gggcatttta tctttgcccg
     7321 gattttcaag gtgcgggtag agaagttcta cctcttcttc gatccgtggt tctcgctatt
     7381 caagtacaag ccgaaaaaca gtgacacgga atacggtgta ggctggcttc cgttgggagg
     7441 atattgtaag atctccggta tgatcgacga gagtatggac aaggaggcga tggcccagcc
     7501 gcccaagcct tacgagttcc gctccaagcc ggccggacag cgtttgatga ttatggtagc
     7561 gggcgtggtg ttcaacttct tgctggcttt gtttatttat tccatgatct tgtttacgtg
     7621 gggcgatacg tacttgccct tgaagaacat gaagatgggt atgaattata gcgagacgtt
     7681 ccagaacgtc ggttttcagg acggtgatat cttgctgaga gcggacaatg aggagttgga
     7741 gcgtttcggt agcgacagtt tccgcaaggt ggtggaggca aagaccgtga cggtgctccg
     7801 tgacgggcgg gagaccgtga tctccatacc ggaggatatg atgcaacgtt gcatgcgtga
     7861 cggaaaaggc ttcgccgatc ctttgcgtat cccgatggtt gttcgtgagc ttcccgacaa
     7921 gaatgccccg gcggctcttg ccggcatgca gccgaaggat agcgtggtgg ctattaacgg
     7981 tgtggctacc ccgacgtttt atgatgcctc tgggttattg tcagagaata agggtgaaga
     8041 ggtgacagta gatttctacc ggaacggcca gttggagtcc ttgaccatga ggacggactc
     8101 ggccgggaaa attggcgtag cggtgatgtt gcctacggat ctctatcaga ccgtgacccg
     8161 caaatacggt ttcttcgagt cgttccccgc cggtattaaa ttaggtatta ataccttgaa
     8221 gggatatgtg aacgacatga aatatgtgtt tacgaaggaa ggtgcctcca gtttgggcgg
     8281 tttcggtacg atcggcggat tgttcccgtc tgtctgggat tggcggattt tctgggaacg
     8341 tacggctttc ctatctatca tcttggcgtt catgaatatc ttgccgattc cggccttgga
     8401 tggcggacac gtgatgttct tgatctatga ggtagtggcc cgtcgcaaac cgagcgataa
     8461 attcctagag tatgcccaaa tggcaggtat gtttatcctg ttcgctttat tgatctatgc
     8521 gaatggaaat gacatcttcc gcttcttctt caagtagcgt atgtctctac agctagatac
     8581 aaaaaacctc ccggatcact tttctatgtg atccgggagg tttttttgta tgaataaagt
     8641 cctctttctt atttcaggat gtcgttgata gaagcgagga tcttcttgga gttctcgtct
     8701 ttcgggtcga gttcgactgc ctttgtcaaa tattctttcg cttgcttgaa gtctttgtcg
     8761 gctttcgctt tctcggcgtt gtatttatcc ggctcggaag tagcgatcgg ggtagcggcc
     8821 tgtaatatct tcgctccgtt gccatacagc atggcgccaa ggctgtagta agcgttgctc
     8881 tggtaatcct tgttcgatac ggctaggacc tctttgtaca ttttctcggc accggccaga
     8941 tctcccttct tttgggcggc ttgtccttgt ttgatgcagt aaccgtaaag caacttttcc
     9001 agattggtct tattcttgtt tccatcggga atcactttta atccctcttt taccgtagtc
     9061 aggaattctt ctgtcttgtt taagttacgg taagccatgg cctcgcctac ataagagtcg
     9121 tctacgttgt agttcatctt aacggccatg tcgaaatact tggcggcctc ggcgtagttc
     9181 ttcgcttgat tagcggcgta tccgcaattg aagatacggg ccgtgtcttg gtaattgttt
     9241 tgtttcaagt attcgccgta ttttgttacg acggtagcgt aatcttttgc tttcaaagca
     9301 gcgtcacctt catctcttaa tttgtcagcg tcttgtgcga ataggtttcc gacacatagg
     9361 cataaagcca ctaataaaac aattttcttc atggtaatta ttaaatttga ttgattttgt
     9421 gctctaagtt aaggcgtgcg ggaaaagaag ccaagatatt ttacgttttt tagaaaacaa
     9481 taaaaataga aaacataaaa aagggattgc cgcaagcaat ccctactaat gaaagattct
     9541 ttggaactta tgctttgagt gaaggaaaag cctcagccac ggcggggtag acaatctttc
     9601 cttccacgat gtttaatccc agttctaggc ccggatcttc ttcgcaggct ttttcccaac
     9661 ctctgtcggc aagcttgatc acgtacggca gggtagcgtt ggtcaaggct aacgtggaag
     9721 tctgcgggac cgctcccgga atgttggcta cgcagtaatg gaggatatcg tctatctcat
     9781 aaaccggatt ggcgtgcgta gtcggatggg aggtctcgaa gcaaccgcct tgatcgatgg
     9841 ctacatctac caatacgctg cccggtttta ataatttcaa catatcccgg gtgatcaagt
     9901 gcggggcctt ggctccgggg attaatacgg cgccgatcac taaatcggtt gtgggtaatt
     9961 cctgttcgat cgtatgcgtg gaagagaaca acgtcttcac gtttttcggc atcgtctcgg
    10021 acagatagcg taagcgggga agcgagatgt cggcgatcgt gacatcggcg cctagcccgg
    10081 cggccatcaa ggcggcgttg tggcctacca caccaccgcc taaaaccaat accttacccg
    10141 gtttcacgcc cggcacgcca cctagcaata cgcctttgcc accttgcggt ttctcaagga
    10201 aacgagcgcc ttcctgtacg gacatgcgtc cggccacctc actcatagga atcaaaaggg
    10261 gtaacgtatg atctgggttc tccacggtct cgtaagccag acagatggag ccgctcttta
    10321 tcatggcaag ggtgagagcc tcgtcggatg cgaaatggaa gtaggtgaag acaagctgtc
    10381 ctttgcgtac caagggatat tcgctggcga tcggttcttt tacttttacg atcatctcgg
    10441 caattccata tacatcctca atggacggga gtatccgggc ccctgccgcc acataggcat
    10501 catcggcgaa accactgttt ataccagccg tgtgttgtac atacacggta tgacctcttt
    10561 tcaccaactc tttggctccg gcgggagtaa gagctaccct gttctcgttg tttttgattt
    10621 cttttggaat tccaataatc ataatggtag catttaatgg gtttatatgc ctgcaatata
    10681 caaaaaagag gaacagattg gtattctgtc cctctttttt tatcttattt cttgttcctt
    10741 ataaaccttg tccgtggcag ttcttgtatt tcttgccact tccgcaagga catggatcat
    10801 tgcgtcctac tcgtttctcg gcacggaccg gagcttgctt cggttgaggt gcctcagctt
    10861 gggtgttgtt tccgctcaag tctgttttct ccgtgcggta acggctcata tcctcgtgct
    10921 tctccggggc ggcctcttgt acggcgatac gttgacgggc tctttcctcg gcgatcgctt
    10981 gggcggcttg ctgggctacg gccgcttgac gggcttgcat ggcttggcgt tgctcctcgg
    11041 tcggctcctc acgtaccggg atctgtccac gcatcaagat ggcggctgtc ttacggttca
    11101 tgttgtctac cattgtcttg aacaggttgt aagattcaag tttgtagatc aacaaaggat
    11161 ccttgttctc gtagctagcg ttttgtacgg agtggcgcag ctcatccatc tcacgtagat
    11221 gctctttcca tccctcgtcg atcatatgca atacgattga tttctggaag gatttaacga
    11281 ttgccttaca ttccgtgtcg taagcctctt tcaggttgca agatacatta tacatgcgct
    11341 tgccgtccgt gatagggatc atgatattct cgtacatcgc tccttgattc tcgtacactt
    11401 gcttgatgac cgggtgagcg acttgcgtca tgcgttccat acgacgttta taagtcttca
    11461 atgcctcctc gaacaatttc tctacgagtt gctccggttt catgctcttg aattcgtctt
    11521 ccgtgaacgg gctttccatg gcgaatgtct tgaacaattc caacttgaag ccctcgaagt
    11581 cctcggcgtg ttgatcggcg atagctgtag aagtatcgta aatcgtgttc aatacgtcca
    11641 gaccgatacg ctctcccatc aaggcgtggc gacggcgggt gtagattacg ttacgttgcg
    11701 agttcatcac gtcgtcgtat tccaacagac gtttacggat accgaagttg ttttcctcta
    11761 ccttcttctg ggcacgttct acggacttgc tcaacatatt gtgctccaga acctcgcctt
    11821 ccttgaaacc aagcttatcc atcaagccgg cgatcttctc ggaagcgaat aaacgcatca
    11881 agtcgtcttc cagtgaaacg aagaatacgg aagaacccgg gtctccctga cgtccggcac
    11941 gaccacgtaa ctgacggtct acacgacggc tctcatggcg ttccgtaccg atgatagcca
    12001 aaccgcctgc gtctttcacg tccttggaca gcttgatatc ggtgccacga ccggccatgt
    12061 tggtagcgat cgtaaccgta ctcttttgac ccgccaaggc cacgatctcg gcctctttct
    12121 ggtgcaactt agcgttcaat acattgtgct ggatcttacg catcgtaagc atacggctca
    12181 ataactcgga gatctctacg gatgtcgtac ccaccaatac cgggcggcct gcctccgtca
    12241 gctgaacgat ttcctcgata acagcgttat atttctcacg ttttgtcttg tagatacgat
    12301 cgttcatatc gttacgggcg atcggtcggt tggtcgggat cactactacg tccaatttgt
    12361 agatatccca gaactcgcct gcttccgtct ccgccgtacc ggtcataccg gataatttat
    12421 ggtacatacg gaagtagttc tgcaaggtga tcgtggcgaa tgtttgtgta gcggcctcta
    12481 cctttacacg ttccttagcc tcgatcgctt ggtgcaggcc atcggaataa cgacgtccgt
    12541 ccatgatacg acccgtctgc tcgtcaacga tcataacctt gttgtccata accacgtact
    12601 catcatcctt ctcgaataag gtgtaagctt tcaacaactg gttgatggta tgtacacgct
    12661 cgctcttaac ggaatagttc gccaagatct cgtccttttg agcttgtttc tcttcctcgg
    12721 ttcctgtcat gttctccaat tgagataatt gggacgtgat atcgggaagt acgaagaagg
    12781 tcgggtcgtc cgtcttaccg gtcaataggt cgataccttt atccgtcaat tcgatactgt
    12841 tgttcttctc gtcgatcacg aaatacaact catcggtcgc ctcgtgcata tggcgcatat
    12901 tctcggacat gaaatattct tccgtcttca acatttgagc ttttacgcct tgctcgctta
    12961 agaacttgat caacgccttg ttgcggggat atcccttgaa ggagcggtac agaaggatag
    13021 agccttcctc aacgaccttc tggtcgtcgc tagccatttt cttcttggcc tcgatcaata
    13081 atttggagca aaggtctttc tgcgcgttca cgacaacctc cacgttcggg cggaattgct
    13141 cgaataattg ttcctcgcca cgagggatcg gtccggagat gatcagcggc gtacgagcgt
    13201 catcgatcaa tacggagtcc acctcatcga cgatggagta gttatgcttg cgttgtacca
    13261 agtctttcgg gctgatcgcc atattgtcac gcaagtagtc gaaaccgaac tcgttgttcg
    13321 taccgaacgt aatatccgcc tcgtaagcct tacggcgagc ctcggagttc ggctggtgct
    13381 tatcgataca gtctacggaa agtccgtgga acatataaag cggtcccatc cactcggagt
    13441 cacgttttga caagtaatca ttcacggtta ccacgtgtac accgttacgt gtcaaggcgt
    13501 tcaaaaatac cggaagggta gccaccaagg tcttaccttc accggtcgcc atctcggcga
    13561 tcttaccttt atgaagaacg acgccaccaa atagctgaac gtcgtaatgg atcatatccc
    13621 atgtgatctc gtttccaccg gctttccagt gattggcgta aatcgcctta tcgtcctcga
    13681 tgcggacaaa gtcgaaacga gcggccagat cccggtcgaa ttggttagcg gtaactacca
    13741 cttcctcatt ctcggcgaaa cggcgggccg tatctttcat gatggcgaat acctcgggca
    13801 aggattgctc cagtactact tccatcttgt ccgtgatggc tttctcaatt ttatctacct
    13861 cggcccagat cgcctcacgt tcttccagtt ccttatcctc gatgcctttg cgaagctctt
    13921 ccacttgcgc tttctcctcg gctacgtagt cttggatacg ttgtttgatc tcatctgttt
    13981 tcgcacgcaa ctcatcgttc gagagtgcct tgattgacgg atatacggcc tttaccttat
    14041 ctacgtaagg tgtgatttct ttaaggtcac gctgcgactt attgccgaac agcttcgtca
    14101 taaactcatt aaatcccatg attcttatgt taatggatag ttgagcaact atcgtctgtt
    14161 attactttgt tgtttgaata attagataat aataaataga aagaagagtc acaacccttg
    14221 ataattatca actttaataa tcaattctct attatttggt tgtcagctcc cagagcggca
    14281 agctttgcgt agcgtttggt ggcctgattc ttagcacatg ggttaccgtg ggggctacct
    14341 cagtggcctt gacttcgcgg tagatatgtt ggggtttcaa cccgttgccc ataaatacca
    14401 gcggggtgat aacagcatta ttgcgtataa tcttgacttt ttctttcgga ttgtcgaggt
    14461 tcactttcca accgggttgc aactcgatga tcagatcgcc ccgtctcaga tgatgcgtac
    14521 cttgacggaa tttggcggtt ccctcgttcc agtcacccgt aagcaagctt ctacccgtag
    14581 tgacgagttg tacgccacta aattcctgta tgaattcggc ggccttgttc tgtaaagtcg
    14641 tcaaatccag cttggcgtct tctatcgcct tgcggttcaa gtagatctgg ttgtcgtagt
    14701 atccttgtac ccagctggta tgttggccgt aaatggccat caagtacata ttaagcaggg
    14761 ctagacaacg tttcgggtga aactcgccac cgttcaccat caagccgtcc ggataagact
    14821 cctcgctttt ataataaccg gaaccggtga agactaccaa tgtattggcc aagcccactt
    14881 tcttgtcgat cgtatccaat agcttctcga tgtcttgatc gagttggtaa tacgtatctt
    14941 gaatctcccg ggtgtattcc ttgctcatcg taccccggta attgcccgca tagtacgtga
    15001 tagacaacat atccgggcaa ctgcgtgtac caaaccctcc gtactctagg aactggaggg
    15061 ccaaacgatt gatctcctta ttgatgaacg gcgaggtctt caggttcgga tagcagttcg
    15121 caaacttctc gctgaacgta tagcggaaag gtagatcgtc taatacgtaa ggaaaggcat
    15181 tgtatttctc cattggaagg gtaggagtcc ataccatggt ttccaagcgt gacgccaaag
    15241 attccgggcc gttattatag cggtctacgt accaagggat tcccttataa tacgtcgtgg
    15301 tagcccattt cccgttggtg ttatccatcc agaaagctcc gttcgccgca tgtccggcgg
    15361 aaaggatggc gctctcggca tccggggcga tggaatatac gtcgcttctt ccttgagagg
    15421 cgattttcaa ctcgtcgccg atcgtggaac tgaataaatt cttgggcgaa taattctctt
    15481 tcgtgtaatt acccagatat tcgggatcat ttaagatcga gacctctttc tctttctcga
    15541 aatcaaatgt cttatctccg gcgataccgc tgaagcaagg gttgcttccg gtaaaaagag
    15601 tcgcaaacgc gctggcttgg tctatgtcag agaactcgaa gcggatattg ttatacacca
    15661 acccctcgtt catcaaacgc ttgaagcccc gttcgccaaa tgtattataa aagtattcta
    15721 tatagtcgcc ccttagctga tccacagtaa tacataccac caatttgggg gtacgctgct
    15781 gcgcctcaag gtttgttacc acgaggatag cgataagtga cgttataatt tttctcatcc
    15841 gattctccat atctttctgt aaacacccca acccgaacga acccaaatcg aggctacaag
    15901 cggaataaag gcactgttta gatgttgcgg aatgaaatgc catcccagta acatcagcgt
    15961 aagcgccgca aagttaataa aatgatagta atatgcagcc ttcttcagct tttttacgca
    16021 aaacaaaata acagcgatca aatcgagcgg ctgtaaccat accaaagacc agttcggcca
    16081 cgtgcaggga tggacggata tgaagctaag aaagaagagg atgacacctc cggctccggc
    16141 taccgagaaa aggacacaat ccacccacag gaagtatttt tttttgcgcc attcgatcca
    16201 agtaagccct aaaacgattc cgaacagaag ccaagcgcag actaaagggg tgaataaatc
    16261 ccagatatct ttttccggct cgtcggcttc cccggctccg atcacgtggg tctcgctcac
    16321 caatgggcgg attgtcccgt ccgggctcgt gatggtggct ttagagaacg cttcttttag
    16381 ataagggggg aggaagagca tctcgtgctg ggtggcctcc cggtcggtgg ggctgcctag
    16441 cgctaggtcg catccgaatg tgagccacgg atggtttcgg gtacaataat taataagatc
    16501 ccggaaggtc tgggattgat agggatactg ataatcgacg ctcccgttga tctccttttc
    16561 caagatcgcg gcagggcggg tagcgcaatt atcgaagaag aagttataac gatataccct
    16621 gttctccggc ctgtaattga taagcagggc gtcccatata tgctctttct cttcttgggt
    16681 gaggttcaat acttgttccg tgatatcgct gccccgcatt tggtactcga tcacgtagtc
    16741 ttggaaatcg gctactccca gtttataatc cgtctctcct ttagcgaatc ggtagataaa
    16801 attaggtttg gagaaatcaa atataccgta attgaatata taatctatat tttgcttggg
    16861 atcgtatatg cgtagagcgg catgcccgta cacggtgaat acctcttcat cgtacggtgc
    16921 gctggtcatc agactgatac gggcttcctc gctcagtttg ggttgcgcta tcgccgatag
    16981 ggaaagaatc cccagcagga atagaaatat gctttttgtc attctcttct taattatttg
    17041 acgcaaaggt agattatttt tcttaaacag tatagatcgt ttaagcataa catatggctt
    17101 tatgtcgaga aaagagatag ctttgttttt attataaagg gaaaaggaaa cttggttacg
    17161 tctttgatta taagaatgtt gcagtttttg tggttttttt taaaaagaaa ctttagtttc
    17221 ttctagggaa aacaaaagtt ttcctatggg gaaacagaag tttcccttgc acaaaactct
    17281 agtttctagc tagagaaaca gacgttgctt ttagaaggag cattgaggag ataaaacaaa
    17341 attaggcgac catccttatt tggataatcg cctaatgcct gatagagcgg taggcgaggc
    17401 tcgaactcgt gaccctcagc ttgggaagct gatgctctac caactgagct actaccgcat
    17461 tgcgagtgca aatgtataca aatctttctt tttttagtaa ctttggcgag aaaattttat
    17521 aaaaaagaat taagtatgga aaaactagtc ttgataaagg taggagggaa gatcgttgag
    17581 gaagaagaaa cgcttcgtca attattgaac gatttcgctg ctatcgaggg atataaggtc
    17641 ttggtgcatg ggggaggacg ctcggctacc aagcttgccg cccaactagg gatcgagagc
    17701 aagatggtga acggtcgccg tattacagat gccgagacct tgaaggtcgt gacaatggtc
    17761 tatggcgggt tggtgaataa aaacatcgta gcgggcttgc aggcgttggg cgtaaacgct
    17821 ttaggattga ctggtgcgga catgaatttg atgcgctccg acaaacgtcc cgtggcagag
    17881 gtggattatg gtttcgtagg cgacgtgaaa gaggtgaatg ccgatttgct agcctctctt
    17941 atccatcaag gtatcgtgcc ggtactggct cctcttacac atgataagca aggccatatg
    18001 ttgaatacga acgctgatac gatagcggga gaagccgcta aagcgttggc gaaacatttt
    18061 gaggtgacat tgatgttctg tttcgagaaa aaaggcgttt tgttggacga gaacgatgat
    18121 gagagcgtga taccggaaat cgatcgtata gcgtttaagg gatatgtaga acaaggaatt
    18181 atccaagggg gcatgatccc gaaactggaa aacgcttacc aagcgataga cgccggggtg
    18241 aagcaagtga ttattacgca agcctcggag attcaccaag gaaaagggac gagagtcttt
    18301 taagatgagg ggctgtttat ggcccctcac gtacattata taataggtct atcaaagact
    18361 ccgaatcttg atattacgga accagattaa tgaatctcca tgttttcctt gtaatccgat
    18421 aaatcctttg gtcggtaatt cggcgaaagg tttgggcaac caacttggga tatcgcttcc
    18481 atccgggttc ttggtgccgg aagtccattt gctcatatcc atttcggtaa ctttctttcc
    18541 attgaggata accatgatat gttgtccggc gcatttgata cgcatatgat tccactctcc
    18601 gggttttttg actaccttgt cttgcacggc gcctagatgt ccgtaaatgg ctccgcattt
    18661 ctcatacggc ttgccgtttc cccatttttc acaatggtcg tccgctatct gtatttctac
    18721 cgagttgggt atccaatcct tcgtgtccgt acagtaaacg actactccgc tgttcgtgcc
    18781 cacgtcggtc ttaaaatcaa gatccagctc gaagttctca tattcatcct ttgtccagat
    18841 agactcgtcc ttcacggcac ctaacacgcc atcagtctcg ctccaaactt ccggattgta
    18901 gttggcgttt tccagatttt taccgaagag aggcttccat ttattgttat ccgccgcgaa
    18961 tgaggagaat gtacttgcca cacaccataa agtagccatg gctaaaagaa aatgtttcat
    19021 gctattagtt ttaaagattt acgtaaggca aatgtattca tttattttgg aaggaacata
    19081 gtctacgaag aacgatttta tttacaagtg aaagcgaaat aggttgaaat gctatgattc
    19141 ttaaggaaat cttctttttt ttatcaaaga tcaaatagtt tgttaaaatg atattaaaat
    19201 cttgtataat ctttattgtt gtaaaataga ttaactaaaa aacacctatt gcttgattgg
    19261 ttttgtgtta ttatgatatt gcttatgtgt caaaatatac atttaatagg tctgtaaatg
    19321 acgttatgaa atatatttga ctgttttaat gacacaaaat catagtatta tttgttttta
    19381 acagaaaata ttctttatat ttgcagtgtg aggattaggt gtatgtgtga ttgtatgtaa
    19441 aagtaaagta aatattttaa tgtaatttta tatatatgca tgtataatcc tgctgtttta
    19501 aactaagttc ttcgtaaact atggtaagtt atgtgtgaaa tttgatttaa ataattaatt
    19561 gttaaataaa aaaagtgtgt ttatgagaag gttgactttt ttgttattat gcttgtttat
    19621 aggcatagga gtcgcaacgg cacagacgat gaagataaca ggtaatgtta tatcatcgga
    19681 agatcagcaa cccgtgatcg gtgcggctgt cgttgtgaaa ggcactacga ttggtacggt
    19741 tacggacttt gagggaaact ttagtttaga tgtaccgaga gacgctaaga tgatctttat
    19801 ttcttatgta ggattgaaaa cgaaggaagt acctgtggca tccgtgatca acgttgtttt
    19861 ggactcggat tcaaaagcgt tggatgaggt ggttgtaacc gctatgggtt tgactcgtga
    19921 gaagaaagcc ttgggttatg ccctgcaaga ggtgaaatct gatgagttga caaaagctgg
    19981 ccaacagagc ttggcgacct cactttccgg taagatcgcc ggtgtgcaga ttacttctca
    20041 aggtggacag gttggtgcgt cgcagaatat cgtggttcgc ggtaattcct cttttggtaa
    20101 taaccaaccg ttgatcgttg tggacggtgt gcctatcgct aatgataatg cgaaaggtgc
    20161 cactgtaaac ttgggttccg gcttgaatga tattaatccg gaggatatag agtccatctc
    20221 tgtgttgaag ggtggatctg ccgctttgta tggtatgcgt gccggtaatg gcgttatctt
    20281 ggttactact aaatccggta agaaagacaa gggtgtatct atctcttatg agggtgatat
    20341 cacgattgac cgggtttata atttgcctag attgcagaat aagtacggac aaggctatta
    20401 cgcttccgag tatgattgga aggaagcgca agcgggggga tattctggcg attatcaaac
    20461 ttttgccttg gagaatggtt acaattatgt agatggtatg gggagtggta tcaacgataa
    20521 cgcggatgag tcttggggac ctcgcttgga tatcggattg aatttgccgc aatacaatag
    20581 cccggtgatc gatggcgtgc gtcaggctac tccttgggtt tcctgcccgg acaatatcaa
    20641 gaatttcttc caaacgggtt attcaatgaa tcatacggtg gctttgtctg cctctacgga
    20701 taaaacgtct acacgcgcat ctttatcttt ccgtgatcaa agcggtacga ccccgaacac
    20761 tgatcagaag cgctatgcta tggcggtgaa cacgaaaatg acgtttaata agtatattga
    20821 tttcgacttg tctgcgaatt atattcgcac gaaaagcgcg aacttgccgg gtacgggata
    20881 taacagtacg aatgctttgc agtctatcat gcagtggttt ggtcgtcaag ttgatttgaa
    20941 ggatttgaag aataattggg atcaagtgga tgagtatgga aaatatacgc attataactg
    21001 gatacagtct ttccatgcga atccgtattg gacattgaat aagaatacca atagttatga
    21061 tcgtaatcgt ttctatggca agacctcttt gtatatcaaa ccgaccgatt ggttaaagtt
    21121 tgaaggtcgt atgggcttgg atcattacga ttctaatcag ttctctcgta ttttatggaa
    21181 tatcgactat ccgaatggat atttccgtag cttcgaccgt tcgatgactg agtttaatgc
    21241 ggactttatc gcctacgtga acaagaactt cggtgattgg gccttgaatg gtttggctgg
    21301 agccaactat cgtgattatc aaacagctat catggggaca ggtgcggacg aattgaccgc
    21361 agagggattg tttaccgtag cgaacgctca tggaaccccg tacaccttga acgaccatga
    21421 gaaacgtcgt tcaaactctg tatacgctaa tgcctctatc ggctacaaga atatggctta
    21481 tgccgaggta agtgtccgta atgactggga ctctacgatc aaggacgctt tcttctatcc
    21541 ttctttcagt ggtagctgga tcttgaccga gacattcccc ggattgcaaa atggcgatta
    21601 tttgaatttc ttgaaattgc gtggtggttg ggcaaagatc ggttccgcaa cggacccgta
    21661 tcgttcgaac gcttattatt cattgatcag ttcttcgttc aatggtacta cattgttcta
    21721 taatccgaca atccttcctc ctacaaatct tcgtccggag agcgtaaaga cttgggaagt
    21781 tggtgttgag gctaatttgt tcaacaatcg tttgcatatt gatgccgcat attataataa
    21841 ggtgacgagc gatcagatca tgaatgcgaa tgtggctacc tctaccggtt atacctctat
    21901 gtatatcaac gctggaaaga tcagcaacaa gggtgtcgag ttgcaggtat ccggtgatat
    21961 catcaagaat ccgaagggat tcaactggac ggctacgttg aactgggcga aggataagag
    22021 ccgaatcgat gagctttata cagatcccgt tactggacag tccttggacg cttaccaaat
    22081 cggtagtagc tggagcgtga agaactatgc tatggtcggt aagagctggg gtactttggt
    22141 aggtactggt tacgtatata atgaggatgg ctcgatcttg gtagaggatg gtattcctgt
    22201 gtacgaggcc ggaaaagaga tcggtgatgt tacgccgaag tggttggctg gtttcagcaa
    22261 tgagttctct tataaggatt ggagcttcgg tttcttattg gatttccgtt tgggtggtga
    22321 catatattct gttacacaag cattcggttc tcagacgggt atcttgaaac acacggcaga
    22381 aggcgatttg cgtgagaatg gcgtcgtact tggccagaat tatatgacgg acaaggtctt
    22441 caagaccgca gatggtaaga ttaatgatgt cgctgtcaac gcggaggact tcttctataa
    22501 ttattatacg atttgtgaga tgtctgtatt cgatggttct tacttgaaat tgcgtgaggc
    22561 tcacctgaca tataatttcc cgaaatcaat tctagagaag actaaatgta tcaaggccgc
    22621 tcatgtatca ttggttggta cgaacttggc gttgctttgg gtgcataagt caaatatcgc
    22681 tcatattgat ccggagtcta caagtaccgg tggtgatgat cccgagactg cggctacaag
    22741 cagaggattc aactctggtg taggttttga gtccaactct tatcctcctt ctcgtagttt
    22801 tggtcttaag ttaggtgtaa cattttaatc aacattaatc tgaggaattt aatatgaaaa
    22861 gatatatcaa gaatttcatg atggctatga tggtcggcgc tactgtattc ggtagctcgt
    22921 gtaccgattc gtttgaggag gtcaatacag acccagatag ccctacggat gtgcctacga
    22981 cgaatcttct ggcgtattct ttatattaca catcctatcg tctgtatgat cggtggttcg
    23041 caatggatga gccgatgact ttctgcggat atgcttcgaa gatgacttat atcgacgagt
    23101 cccgctataa tttccgtacg ggtgtacagg atacgaactg ggagtatttg tatcgtatat
    23161 tgaataacct gaaagatatc gagaagcgtg ccacgtttaa tgagactcct aatatgctga
    23221 acgtatcgaa ggttatgcag gttcatttga tgcaggtggc cacggatcgt tggcgtgatg
    23281 tcccttatac ggatgccgct aagatgacgg atggaatctt gcagccgaaa tacgataagc
    23341 aagaggatat ttatccgggc ttattggcta cgttgaagga agcagcggat ggctttgccg
    23401 atggtggtag tgatgactta ggcgagggag acctgttatt cggtggtgat atcgagaagt
    23461 ggcagagata ttgtaattct atgcgtcttc gtttagcgat gcgtatctca gaggtttccc
    23521 cggcgttggc taaggagacc gtagaggaag ttatgggtaa tcccactaag tatccgatca
    23581 tggaaagcaa cgatgataat gctttcttct ggtggatcgg aacagacccc aactattacg
    23641 aaccgatggc agacggttat cgtacacgta agacggagta ttgtgccgca gacgtgatcg
    23701 tggatcatat gaatacacgt gaggaccctc gtcgctcatc ttatttccaa cccacaaaag
    23761 aaagtgtgga ggccggtgag cctaagtatg taggttatac gatcggggcg aaagcgaatg
    23821 cggtagcttc taaatattcc atttggggag cacgtttctt tacggacttg gctggttttt
    23881 ctccttatat gcgtgtcgct gagccttggt tctgtgtcgc tgaggcatct atgttgggat
    23941 ggaataccgg aatctccgca gaggacgcat acaataaggc tgttacctat tccatggaag
    24001 agaatagcgt atctgccgaa gatatagcgg attaccttgc gaacgcgggt aagttcacga
    24061 atgataagaa acagatttat tatgaggaat gggttgccat gttcaagcaa ggaatggaag
    24121 gttggtcatt gtatcgccgt acaggcgtgc cagacaactt gtatccggct ccgggccgtc
    24181 cggcaaacta ttctaatcat aacgtacctc cattccgctc tccgtatcct gataaggaac
    24241 gtaatttgaa caatgcgaat tgtgctccct tcgatgcgga agtcgtggat aatttgtggg
    24301 gtaaacaaat gtggtgggat acacgtacag gcgttcatta actactagtt aacatagaca
    24361 taccaagtgc ctgtatacta tagaggggct gctcgtgatg agtggcccct ttttttgtca
    24421 ttatgctgtc attttttaat aaactatgta tctttgtccg gcttatttag aaaaaagatg
    24481 gaaaaagaag gaatgatggt ggtcgatatt aagaatatcg ttactcgttt gccggaattg
    24541 cggtttacgg cacccgtgaa ttggagaatt gatgaaggac agcaatgggc tgtaatcggt
    24601 ccgaatggcg ctggtaaaac cttgatagcg gatattatgc agcgtaaatt cgcttttaag
    24661 gaaggtgagg tcgtgttctc cggggatggt aaggtgagtg actttatcaa gagcatagcg
    24721 tttaaggata tttattcgtt ggcggattgc cggaattctt attaccaaca gcgttggcat
    24781 tcgacagaga cggaggagat gcctattgtc gaggaattgt tgaaggaata tgccggctct
    24841 gataatttag cgaagatatt gactcttttc ggtatagagg atttattgcc taagcggttg
    24901 atcttcttat caagtggtga attacgaaaa ttcttgattg tccggacgtt gcttagccgt
    24961 cctcgtgtct tgatcttgga taatcctttt atcggcttag acgctccatc ccgggattta
    25021 ttggtagaga tgctggggca aatgacaaaa ttgaatggcg ttcaagttgt cttgttatta
    25081 tctaacccca atgacatacc ggcaatgatc acgcatgtat tgcctatcca tgatcgtact
    25141 tgcctgcctc cgctgactcg agaggagttt atgtcggata cggaattaat cgcccgtctt
    25201 tttccaacgg aaggcattca tgcatgcgag gaagttggta aggttcgttt acctgtggat
    25261 atgaacaaga tagcctcttt acatgaggtg actttacgca tggagcatgt gaaaatacgc
    25321 tatggtagcc gtacgatctt gaaagatttg gattgggaaa tcaagaacgg ggagaagtgg
    25381 gcgttattcg gtccgaatgg cgctggtaaa tctaccttgc tgagtttggt ttacgcggat
    25441 aatccccagt cgtatgcgaa tacgttgtat ttgtttgata gaaagagagg ttccggggaa
    25501 agtatttggg atatcaagaa gcgtatcgga tatgtatcgc cggagatgca cttatattat
    25561 aaggagaatg tccctacctt gaatattgtc ggttccggct ttttcgattc gatcggcttg
    25621 tttcgtaagt gtaatgcgga gcaagaaacg gtagccttgg agtggatgaa agtttttggc
    25681 atcgaacatt tgaaagaccg tttattcttg accttatcat cgggagaaca acgtttggct
    25741 ttattagcga gagctttcgt gaaagatccc gatttaatta tattagatga gcctctccac
    25801 ggtctggatg tgagcaataa gaaaaaggcg gctgctatta tcgagcaatt ctgcgatcgc
    25861 ccgggaaaaa ccttgattta cgtaacccat tacccgcatg aattacctgc ttgtgtagac
    25921 aagcggttcg agctagtgaa gcactcgtga gcgtacaaag aaaaagagga tgtgccgtgg
    25981 tgaagtggca catcctctaa aatcaataaa tacttatgga taaaggatta atatcctggg
    26041 ttctgtatca actgacctct tgatacggtg atttctccga taggaattgc catgatcgta
    26101 cggtaatcgc ccggcttaac ctcacctacg aatttattgt tgacagactt gccgttacgc
    26161 caagcgtccc aagcggtatg tccttccgtg aataattcta ggcgtctttc cagtaagata
    26221 tcatccaacg tgatagaagc gacatcggta taattctcaa tacgattctt gcgtaacgta
    26281 ttcatatatc cggcggccgc ggaggtatcc cctgctttta gtgcggcctc ggccgctatt
    26341 aggtaaactt cggaaaggcg cacgaccttt ggattgttta catagatttg cccgtcacgt
    26401 cccttatact tttgcggata ggtcccgtca tagccattat cggtctcttt tgcgaataat
    26461 tccgtacgga tatctcccgg atgcttagcc agctcttcca ggaaagattc agtagcggca
    26521 cattcaccgt agccggaggc atgtgtaaaa taaccgatag agttacgttg cgcgttataa
    26581 tttggggtaa ctaagatctc gaatatagcc tcgttcgttc cttccttatc ccatgcgcct
    26641 atatattcat cccgtgtgta taacttataa ggagaggaag cgataatctc cttacagtca
    26701 gccagtgcct ctttattctt ttctaagtaa aggtaagcgc gtgcgcggat cgctaaagcc
    26761 ccccaataat tgatgtgtcc ggtttgttta tctttactca aaagaggcaa tgcggtctcg
    26821 atatctttca atatctggtc gtatgtctgc tgtaaggttg cccgggtccc gatataatcc
    26881 gtgggataaa cctctgtgga gagtacgatg cccagatcgt tcatatctgt tgttgatggt
    26941 aatttagcga atactctggc taaatcgaaa tgatacaagg cgcgcatagc gtatagttct
    27001 cctttcaata tgtctacatc cgcaccttca agattctcgg cggcggctaa tacattatta
    27061 aggcgagcta gactattgta gaataattta tagaaactat aaaccatctc atcgttttta
    27121 cctgtttggt aacgatacat ggggccggca tgattcaccg tggagataga ttggaaatcc
    27181 ccacttcgta aatcggccag caatgtgaat tccgctccat acgagcctac ctctgtagcc
    27241 tgttgctcgt atacgccatt cacggcattt gtcaaatcgg ctacggaaga gattgcgtct
    27301 atcgtaggta attgggtaga tgatgtcttt tctaggacat catcgcagga ggccgttaat
    27361 aaggcgaacg ctagacctac taaatatatc tttttcatat agattctatt ttaataaatt
    27421 ataatgtgat gtttacacca aagacaaagc ttttagagac cggggtatct acctggcgat
    27481 aaccattcaa gggaacatcc gggtcgatgc cttttgtctt tgcccagatc atgaacggat
    27541 tattcgcacg gaagtacaca cgcagattac tgaatatgtt tttcaatacc ggtacattgt
    27601 atcccaaggt gatttcacgc atacggatat tgtcagaaga tacgatggta cgactggaga
    27661 agcgatccga gcgatatgga ttctggtaga taggcttcgg gtataaggcg ttgtcgcccg
    27721 ggttcatcca ataattaccc gctacgctct tttctaggtt gaatgaacct aaacggaatc
    27781 cgtcatgatg gaagaagtag ttcggataat cgaatatatc gccaccaaat tgataggtaa
    27841 tcaagaatga aagatcgaaa tcatataacc ggaacgtgtt tgtcaaacct cccgttacgt
    27901 cgggaatggc tttgcctacg attccttttt cagcctcatc gtacttgttc actactcctt
    27961 tgctatgatc gtttggatct ttccagaatt ctcctagtcc tgtatccgga ttcacgcctt
    28021 tccattccgg cagatagaaa gtatacatgg attctccctc tcggtgcaga tacatatcgc
    28081 cgtctccata ttcgatgtcg ttatggttcg gcaattcctt gattgtcgcc ttctggaatg
    28141 taaggttgaa attcgtgtcc catgagaagt gctgattctt gatgttttgg gaatttacct
    28201 ctatctcgat accgctattg cgtagcttac caaggttttg ccagtttttc tcaaaacctg
    28261 tgacgataga agtcgggatc tcgaataaca ggtcggtcgt tgttttgttg taatattcta
    28321 ctgtcagatt tactcggttg aataagttcc agtcaaaacc cacattcatg tttttggact
    28381 tctcccaacc taattcctca tttcctgctt gattccaata gatggcggaa gaggggccat
    28441 aaccaccaga gaacgcatat aacgcttggt tcgcgtaata tgagcccggc aagtttccat
    28501 ttgtaccgta agagaagcga acttttagat cagagaacaa ttcattgtct ttaaggaaat
    28561 tctcgccact gatgcgccat gcgccagata cggaccagaa attcgcccag cgattatcgg
    28621 ttcccaagcg agaagaacca tcccgacgga aactggcaga cagatagtat ttattgtcgt
    28681 aattatagtt gccggtagcc aagtaggata cgattccgga gccaaatact tcgctggatg
    28741 cgccatctgg ttgtccgttt cctaattccg gtaacttgtc ggttgagtat tgttttgccg
    28801 tagtatagat ggctgtcagt tcgtcttctg ttacctcgaa accacctagg atgtcaaaat
    28861 tatgaacatc gttccatgta ttagcgtagc gtaacgtgga agaacttgtt aaattgcggt
    28921 tctcgtaagt atagcgagat cccaagccgc ctacggcctt accgtccacg ctgttgggag
    28981 accaatactc aaagtgtttc gtatcgatat agtcgtaacc aaaaatcgtc ttgaacgata
    29041 attgcttgga gaattttacg cctaaatcaa tgttagacat actacgcatt acacgggatt
    29101 taatccattg ttccttgccc aacattagat gcggattgga agcggcaccc cagtttgagt
    29161 cggcgttgta tgtaccgtcc ggattcttta cgggagccgt cgggtctgag gagtacacca
    29221 agctcagtgg agaagcagta ccgatacctt gatcttgatt ttgctgatca cggaaaccat
    29281 tttgggtagt gaatgcgatc atttgcttaa caccgatagt caaccaatta tttacttgat
    29341 gatctaaatt gatacgaccg gagaaacgtt cgaaatcgct accgattacg ataccttccg
    29401 cattattata accaagacct acatagaatt gtgtacggtc gttacctccg tttacggata
    29461 attgatggtt atgcgtcaag gctgtacggt aaacctcatc acgccaattg gtatccgtgt
    29521 tacccgatgg gtcgttgaag aatgcttcca tgtcgccttc cttgtcaatc aaggcgtatg
    29581 cttgatcacg gttgccagcg agtccgttta ggatataata attggaaatc gcttcttttc
    29641 cgtacaggag caattcggag gcattcattg tctcgtactg ttttacagcc atattgctcc
    29701 agccgacctc gccattgtaa cttactttcg tcttgcctct ttttccggct ttggtcgtaa
    29761 tgatgataac gccattcgct gcacgagagc cgtacaagga agctgctgcg gcatctttca
    29821 acaccgtcat gctctcaata tcatcagggt tcaaggagct tagcaaactg gactgtttcc
    29881 cgtagtatgc catatccgag tctgatttta caggcacgcc atccacgaca tatagaggag
    29941 acttggctgc gctgatagag ccgacaccac ggatattgat atcaccggga gctcctggat
    30001 caccagtgtt ggaggttacg cgaacaccgg acatctttcc agaaagagcc ttatccaagg
    30061 actctttgga gccagctacg atatcttctg cgtttaccgc tttagcggat cccgtgaaag
    30121 atgatttttt cgccgtacca taagcgacaa ccataacttc atccagctct gtcgccgccg
    30181 tattcaaaac aactttcatt acatcttgga ttggagcttc tttcgcaacc attccgacgt
    30241 atgaaaatac cagagtcttc gcggaac
//
LOCUS       DBMDTB010000041        29489 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_582_length_29489_cov_11.727372, whole genome shotgun sequence.
ACCESSION   DBMDTB010000041 DBMDTB010000000
VERSION     DBMDTB010000041.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 29489)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 29489)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29489
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_582_length_29489_cov_11.727372"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..1881
                     /locus_tag="ACZPB4_08340"
     CDS             <1..1881
                     /locus_tag="ACZPB4_08340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor plug domain-containing
                     protein"
                     /protein_id="HIR1098266.1"
                     /translation="VEKVRPSVTREGTPLQIMDRAGIDRLGVQDLSEAVKRFSGVTVQ
                     DYGGIGGLKTVSVRSLGAKHTAVSYDGVTITDAQSGQVDISRFSLDNVEMVSLSIGQS
                     DDIFQTARVYASAGALNIQTGKPTFKDKSFHTYLKVKGGSFGLFNPVLHYDQKLGKRW
                     SASLHGDFVRADGQYPYTLINGELETREKRRNSDIHSFHLEGNLFGDFGRGGELSFKA
                     YYFDSERGLPGSVNLYNKNTSERLWDNNFFVQSGYKNVLNEKFTLRAMAKYNYAFTRY
                     LDINDKYAAGEQVDLNTQNEYYGSVGLLYTPIKYVSATLTTDLTRSMLDNNFVNGPNP
                     KRMASQSVLAVQYKNSRFTATASLLGTYITDKVEQGEKPDDKRRLSPAVSLSWRPFSE
                     STLRIRASYKDIFRVPTFTDLYYLRMGNTNLKPEETSQYNVGVTWSSSCGDWLRHFSI
                     SADGYYNTVKDKIVALPTMYVWKMMNMGEVDIKGVDVNLSTQFRLPLRMSLLLASTYS
                     FQYAVDVTDPEAKNYKDQIPYTPRHSGTVSVTLENPWVNVSYILTAVGDRYALPQNID
                     RNRIDSYIEQSISINRDFRFRYFGLRLQGELLNLANVNYDVIQYYPMPGRSWRLSICL
                     SY"
     gene            1902..3266
                     /locus_tag="ACZPB4_08345"
     CDS             1902..3266
                     /locus_tag="ACZPB4_08345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5074 domain-containing protein"
                     /protein_id="HIR1098267.1"
                     /translation="MKKKNLVCVSALCALMSFSFVSCDDDNEPSLNIPNVSVTNVSFT
                     DENPEALKVSGTLNWTAPSSVDNVTKYVIYGSSDGTAKDMKIAEVEVGTHSYAITDVV
                     NIGYLLVIAANAEGESSVYASVRVIDFVKDSSFMALYFLNSGNMGNNNSSLYMYDIEK
                     DEVVPDYFLAQNGRGLGDTAQDMIVYGDKMYIAVYGESTIEVTDLKAKSIKQVKTEGQ
                     PRYMVSEGGKVYISYYNGYVARLDTASLEVEAKVKVGRNPEQLAVSSNKLFVSNSGGM
                     DYSTEVGYDKTVSVVDLSTFTEIKKLDVVLNPTRIQADEQGNVYVVSMGNYADIPNTV
                     QKINTETYEVTSLTNCPNATEMAYEDGKLFLFYAQWGMSSPAFLTFDTKSQSAGTSFI
                     TDGTSIQSPYSISAVGGNVYVAESDYKNNGDIYCFGGDGKLFKKFEAGLNPMKVVLAQ
                     KDNI"
     gene            3266..4384
                     /locus_tag="ACZPB4_08350"
     CDS             3266..4384
                     /locus_tag="ACZPB4_08350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HIR1098268.1"
                     /translation="MRLLILLGFAFWMVACTPSGKQTSSKEALSSDSIQYAQGFTVQR
                     FDTYIMVEVRDPWDSTRLLQRYLLVDRTKSVPGGLPKGTIVKVPVKDIVIYTSVHAAI
                     IDQLHETDKVIGVCEPRYMDTPAIQEGIQAGRIADLGEATSPNIEKMIEIGAELVIAS
                     PFQNSSYGPVEKIGIPIIEGADYMEAFPLGRTEWIRFYGLLFGKEEMADSIFKETEQA
                     YLSLKDLTANIDNRPTVLSEKKFGSSWYVPSGDSYMAHLIEDAGADYMFKDLPGAGST
                     PLAFETVFDKAIHADIWLVKYNQSSEMTYNDLRSEYTPYENFDAFKKKRIYTCNTGAV
                     PYYEEFPIHPEYLLKDLIWIFHPELVFGYSPRYFREMP"
     gene            4448..7219
                     /locus_tag="ACZPB4_08355"
     CDS             4448..7219
                     /locus_tag="ACZPB4_08355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding and (Fe-S)-binding domain-containing
                     protein"
                     /protein_id="HIR1098269.1"
                     /translation="MKIKKVYADALTTLAKGTDAGIYRLNPKRVEIVSCEQDVKRVLA
                     ECEKTGKSVTFKAGGTSLSGQTITDSVLMEISPDYGKVKISGDGSLAKFPCGITGEEA
                     NRWLKPYGRKLGPSPASIKSARIGGIVANNSSGSSYGIIHNSYNTVRDMEIIFADGAF
                     LDTSSLASRRDFMQTHIGLLEKLMNFRLEILLNPDMEDRILSKYELKNTCGYGMNSFL
                     DYTDPYDILMHLMVGSEGTLGFISSVTFETVPDEALKASALIYFPSLMEACRAIAPLR
                     QCKVSAAELMDRNALHAVEDEPGMPEILHSLPEDAVALLIDTSSNSEEELQIQFRDIE
                     ERLADIQTLYPVSFTTDPKLYATYWRVRNGLFTSAAGRRPRGTVSIIEDIAFREEVLG
                     EALEQVRGVLSDYGYGNAVMWGHLLDGNVHFTIFPDINAQEGIDHYASFMRSLVDVVL
                     YYDGSLKAEHGTGRNMAPFVKDEWGEEIYELMWKIKRLFDPENILNPGVLLNRDPDVF
                     IKNLKQIPLANELIDKCIECGFCEIQCPSRHVTLTPRQRIVIYRELSALAEQGETNSK
                     RYKELKKAFNYKGNATCATDGLCATACPVGINTGLLIKELRWKENGVLANAIASGIAG
                     NMGTVTGMLRPLLKLPHVLSKLVGYNAFERFASFLFRASAHKFPLWTRHTPSGASKFK
                     ELTGVENGMEMVYFPSCITRTMGASADYEDVDFVSVTEQIIALLTRADFTIRYPENLS
                     KLCCGMAFSSKGFRKQAAQKAEELNEALLRASDNGRLPILCDMSPCLLHMRETLDKRL
                     RLYEPVEFIYDFMRDRLNFTKLPVTVAVHSTCSTTKMGVQDKLVELAGLCANRVVSPA
                     QVTCCGWAGDRGFFYPELNASGLHYLKPNLHGATEGYSNSRTCEIGLTMNSGISYKSI
                     VYLVEKATR"
     gene            complement(7320..8696)
                     /locus_tag="ACZPB4_08360"
     CDS             complement(7320..8696)
                     /locus_tag="ACZPB4_08360"
                     /EC_number="1.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003954 - NADH dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006116 - obsolete NADH oxidation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HIR1098270.1"
                     /translation="MMKHELEKQLDALEKKGVDRRHFFKLLAATGLIAGANTGKANAF
                     SSSAKGKIVIIGGGAAGISMAARLKHWLDEPDITLIDPSDRQFYQPGFTLIASGVYQP
                     EDVWKKQEDCMPSGIKWIKDSVAAVDPVWNQVTTKSNGKIPYDFLVLTPGLQCNWEKV
                     EGITHDTLGQGNANSIYDFEGAQKTWKALQEFAKKGGKGIYTDTYTKHKCGGAPKKIC
                     LLSEHYARKQGTRDKLQLNYFTASKELYDIPYFTPRLLEIYNERNIPINLNVRVKGVD
                     TSAKQVHFEKIETKGEEKIVTPFVEDYDFLHFTPPMSAPDFVRDAGLGWTEGKLAADA
                     WVMVDKETLVHKKYQNIVSLGDVAGIPTSKTSAAIRKQVPIAAKNLIALMEGKEPTEK
                     YNGYAACPIVTDYGHVLLCEFDYEKKPDISFPFSMIDTSKEQWLAWILKVYILKPMYF
                     NGMLNGYA"
     gene            complement(9094..9687)
                     /locus_tag="ACZPB4_08365"
     CDS             complement(9094..9687)
                     /locus_tag="ACZPB4_08365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098271.1"
                     /translation="MKVNENTIYIFLLGILAGIICMQCVNHFRKSPKDVYVDNFEYEK
                     ESLGILKREELKNEHYECLDQIAYWGTDSLDSFSLSNLCNDKKLFFCFSEKTCPPCID
                     AVVDIMNEVFTDEEIKTKIVFVSPDYPARLRNDCYGKKLLSLHNKNLGLPMELEDSFA
                     PFLFIMDKDLCVKYLHIHNKPLPRLTLIYLEEIKKMW"
     gene            complement(9677..10810)
                     /locus_tag="ACZPB4_08370"
     CDS             complement(9677..10810)
                     /locus_tag="ACZPB4_08370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-bladed beta-propeller"
                     /protein_id="HIR1098272.1"
                     /translation="MKSIIYYFSMISIFFFLSCTGWKDKKNMESDIITVNLDERDEIS
                     TKDLFSEIQLIPLETTPESLIRNITQIKFFEDRYYIHDYSRSQIFVFDREGHFQFALN
                     EKGNGPGEYLNLTDFAIDTTRRNLVVLCAVSNALFFYDLGGKFIEKKKLPEIAGAYNS
                     LQFQNKDTIAFFTYDYDHRLKFYSLSRNEILDEYFPEDIKDVFCRGVFPFPHAFRRSL
                     TNTIYSLSGATFTELYRWDFGDLNNDIEKLEFHPNMSKQEIIQYAKDVYSSKSVNYII
                     DSQGQNSRYRYAMVVRQNKYIQLFYNRKNHDLLQFERTKEGLQLYPIYFGEDFILCTP
                     EGGLPLNDLFPEKLRNEDQQRIIQSHSEQENPVLVKYVFKNEG"
     gene            complement(10816..11055)
                     /locus_tag="ACZPB4_08375"
     CDS             complement(10816..11055)
                     /locus_tag="ACZPB4_08375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098273.1"
                     /translation="MGKRFFKFTALISLIFFAINVDVLAEGDSDDHACPDGDQGPVIS
                     CGRYEGTCWNVDWISGIYYVHCYFSGMQEHHCYPD"
     gene            complement(11310..13370)
                     /locus_tag="ACZPB4_08380"
     CDS             complement(11310..13370)
                     /locus_tag="ACZPB4_08380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140299 - molecular sensor activity
                     [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ligand-binding sensor domain-containing protein"
                     /protein_id="HIR1098274.1"
                     /translation="MYRRLPFIILLSILAVFALRASVVAPSILVQNYSVDDYKASCQN
                     WDLAVSYHGILYVANNSGLVTFDGNTWNTYPLPDKTPIYKVSFQNDSIYTQGKSSLGY
                     WLYDKLGNLEYHPIDTLPSYINFDDPETNYTIPKEIEEKHPTSFASAGGLNFTGTSTS
                     GIYITNDEGEIFQHLNINNQLQDNIVRSICVQDNNLIWVALDNGISQIDINPPIAMLG
                     KRSQIGKLEDAVKEDNRLYIRTNVGYFSRSLMFGDKFTPISDEIGRSYIHPDTTDNHL
                     SVSSLFKNKDVLSVFANAESIYPVPDNLYWLTIQNEAGLFHRENGTGTLKCRILFDNY
                     DLNLVTNGKRIIPLNDSLDLVSAMQGTLLINTRQLIEGSLGGLTMPRFMRIEYQDQEG
                     THYLYPDTQRIDLPHNFQELSLYIGTTVFTPNHQISYKLEGVSADWSSWQKDGKITFL
                     QLPEGTYELRVRKYVTRGPFPEITMQITVRPPWYNTVWAYLIYVALIWFAIQEGLRYH
                     LRNLRKKEQEKLEAERQAELQRLQQMKSEMLETELQNKNNELTLQTTALVKRNEAIQA
                     LLEELDKQKETLGDRYPNKLYTRLRSLIESTLNDQADWVQFETYFNSAHQNFMDRLRQ
                     QYADITAGDLRICCLLRMNLSTKEIASLMNVSVRAIELRRYRLRKRLALDGDTNLVDF
                     LMNY"
     gene            complement(13448..16666)
                     /gene="carB"
                     /locus_tag="ACZPB4_08385"
     CDS             complement(13448..16666)
                     /gene="carB"
                     /locus_tag="ACZPB4_08385"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009016854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005951 - carbamoyl-phosphate synthase
                     complex [Evidence IEA];
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) large subunit"
                     /protein_id="HIR1098275.1"
                     /translation="MSKSDIKKVIVLGSGALKIGQAGEFDYSGSQALKALKEEGISTV
                     LLNPNIATIQTSEGVADKVYFLPITPYFVEEVIKKEQPDGILLAFGGQTALNCGTQLY
                     TSGTLAKYGVKVLGTSVEAIMYTEDRDLFVKKLNEIEVKTPISQAVESMDDAVAAAYK
                     IGFPVMIRSAYALGGMGSGICKDEAELRTLAESAFAYSSQILVEESLKGWKEIEFEVI
                     RDKNDHCFTVVSMENVDPLGVHTGESIVVAPTCSLTEKELDLLKELSTKTIRHLGIVG
                     ECNIQYAFNSETCDYRVIEVNARLSRSSALASKASGYPLAFVAAKLALGYGLDEIGEM
                     GTPNSAYKAPEVDYMIVKIPRWDLTKFVGVSRQIGSSMKSVGEIMSIGKSFEEIMQKG
                     LRMIGQGMHGFVGNNDIHFDNLDEELANPTDLRIFAVAQALEQGYSVDKIHELSKITR
                     WFLEGLKNIVDYANVLKGYNKIEDLPEDVLKEAKRLGFSDFQIARYVESPEGNMEKEN
                     IRVRNLRKKMGILPTVKRINTIASEHPELTNYLYMTYDGTPHDITYYPNEKSVIILGS
                     GAYRIGSSVEFDWCSVNAAQTARKLGYKSIMINYNPETVSTDYDMCDRLYFDELSFER
                     VLDVIDLELPKGVIVSVGGQIPNNLAMKLYRQNVPVLGTSPLSIDRAENRHKFSAMLD
                     SLGIDQPRWAELTSMEEIDAFIEKVGFPILIRPSYVLSGAAMNVCHTKEQMIEFLDLA
                     AKVSKEYPVVVSEFMQGTKEIEFDAVAMNGEVVEYAISEHIEFAGVHSGDATLVFPAQ
                     KIYFETARRIKKVSKMIAKELNISGPFNIQFLAKNNFVKVIECNLRASRSFPFVSKVL
                     KRNFIETATRIMLDAPYTKPDKSAFDIDWIGIKASQFSFARLHKADPVLGVDMSSTGE
                     VGCIGDDFNEALLSAMIAVGNSIPKKNILVSSGAAKSKVDLLEPCRMLDAKGYTIYGT
                     HGTAKFLNDNGIKATAVCWPDEEGDLNIMDMFSNHAFELVVNIPKDHSKRELTNGYKI
                     RRAAIDHNIPLITNARLASAFIDAFCNMNVEDIQIKSWQEYK"
     gene            complement(17015..19306)
                     /locus_tag="ACZPB4_08390"
     CDS             complement(17015..19306)
                     /locus_tag="ACZPB4_08390"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HIR1098276.1"
                     /translation="MKTNNLIYLLVIVLLSSIHCDVNAQYYWSQNRKIALTPDSSHLV
                     LNIEADLIRTPMLSSDYKGFNEISPNIIVKENKSNIFSENDFKAYESDPLVKRASPAY
                     LVNGTDTLYVTNHILLKPKNGVSIDSILAGMNEIVEVVDQTKYGVYTLSVNQGFDVLT
                     YANIIYENGLVDFCHPDFIMRITQFLNDPLYSEQYYLNNTGQLGGTWNIDINAPEAWS
                     MTKGSSSIKVAVIDQGVAGHEDLGDRLLPGFTPGLANGNGAPVSNNPHGECCAGIIGA
                     SHNNLGIAGIAPLVKIVPVNIFYSQSSSNIAAAINYAWDDAEADVISNSWGGSVADAI
                     TSAINNARTNGRGGLGCVVVFAAGNSGSSVSFPATVNGVIAVGAVDKNGALCSYSARG
                     SEINLVAPSGALDYTGDIRTLDLMGSAGLYPGNYLSTFGGTSASCPQVSGVAALLLSI
                     NPKLTEAEVRNILGHSARKIGSYSYSTVSGHPFGTWNANMGYGLLDAEAAVREVYPQI
                     SGDNLVPCTGNKTYTLNRNYKGNWTLGTSGLQIVSGGQNSNSITVRAISNPGGTMSGT
                     IYANVVLPNGSSVSVAKTVSIGAPSITSVSGPDQVGAGGSASFTASPIFMEDEGNYQW
                     MVSPNTASMSAYRYSNSVTFSAPGTYIVGCRSTSTCGTPGSYVIKTVSVTGYYYSVST
                     SSSTHMVNISKETQIQDQFSVMLETRPTYTLYNQSTGALVREGTFLREGDLLDFNTLP
                     SGIYVLRLQIGNDTYETHKIVFK"
     gene            complement(19303..19719)
                     /locus_tag="ACZPB4_08395"
     CDS             complement(19303..19719)
                     /locus_tag="ACZPB4_08395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098277.1"
                     /translation="MQKLKTKITGLAFFLVIVCISCDKDDRLVGFVSMIALENNNICL
                     VAIHEGPKLGVTGLNFSNAIQLYIPDNRTVKLAYTIKFNCRAYDPAIDGVILDAFTIP
                     HPSESYDPRDPNSEYLSNKVPMYIAENVEIIKYELE"
     gene            20079..21798
                     /locus_tag="ACZPB4_08400"
                     /pseudo
     CDS             20079..21798
                     /locus_tag="ACZPB4_08400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772852.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            complement(21948..22304)
                     /locus_tag="ACZPB4_08405"
     CDS             complement(21948..22304)
                     /locus_tag="ACZPB4_08405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6078 family protein"
                     /protein_id="HIR1098278.1"
                     /translation="MRQAVCVNTPIPERRNKQSPLTRRHLASLKGTCPYYRPNKKVRY
                     AAGFVSLLESLPHKQMLSVIPGLMRHFSRRTYYRVRKGERPLSPSEQQVVLNALKRCG
                     VKEPKDFDAYFEEYDW"
     gene            complement(22349..23695)
                     /locus_tag="ACZPB4_08410"
     CDS             complement(22349..23695)
                     /locus_tag="ACZPB4_08410"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 10 protein"
                     /protein_id="HIR1098279.1"
                     /translation="MRHINYLVLLLVACCVGACSSPKNDTKDAYPMFWTWLDYQPGMN
                     FDSICTIMNEAGIDGVMLNAPTPDDYRAAIPIAQKHGIEVYAWLWTMNPEHDRDAILK
                     EHPEWFSVNRNGQSLADTTAYVDYYKFMCPALPEVREFIKKKIEAYCEVEGLNGIAID
                     YNRFVDVILPTTLWPKYGIVQDQEYPQWDFGYHPAMIEKFKAAYGYDPKEQEDPSQDE
                     KWLQFRCDQITEVANMIADVVHSYGKKMAASPFPTPKMASKMVRQDWGKWNLDIVFPM
                     VYHNFYTEDISFISDCMIEDVRDKNPKTTLYCGLMVADDIENAMDAALNHGAEGISIF
                     TVSALRTPESRAMFKAYADSVRAVRAENNGVNPALSKSTKVTNPFESMDILNRINAKI
                     KELANVPIPNIADYKLVNEKGATKYYEVKELNTGKTFCVDFYFYGGILSGWNVTVK"
     gene            complement(23748..26978)
                     /locus_tag="ACZPB4_08415"
     CDS             complement(23748..26978)
                     /locus_tag="ACZPB4_08415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HIR1098280.1"
                     /translation="MGSKPNISSFTIIVTFLCIALAGIAFVPLLPIKLSPSRTLPKLS
                     ISYNMPSNSARVIEMEVTSRLEAMLARIKGIKEISSTSGNGWGRITLELDKHTNIDAA
                     RFEASTIVRQTWPDLPEELSYPILEMSRPDDKESRPFMSYTLNASATPIFIQRFAEDQ
                     IKPRLSSVQGIYRIDVSGATPMEWRLEYDSRQLRDLGITIEDIQSAISQYYKKEFLGT
                     ANMGQGDTSKEWIRLALMPEKITNGFEPSHITVANKDGSLIRLDQLIKVTRQEEAPQS
                     YYRINGLNSIYLSIRAEETANQLQLAKKVKEEMKHIRTLLPPGYEIHTSYDATEFIQE
                     ELDKIYVRTGLTILILLLFVLLITRNVRYLFLIIISLSINLCIAVILYYLLGLEMQLY
                     SLAGITISLSLVIDNTIVMTDHIRHHHDRKAFLSILAATLTTMGALVIIFFLDEKIRL
                     NLQDFAAVVIINLAVSLFIALFLVPALIDKMNLHRKKVASSSPKARSHWRQHPVVRPI
                     RSFIHRFPVYFSHYYRAQIRFLCNWKKLACLILVLAFGLPIFLLPEKIEPEEKDLSAR
                     DSLWIARYNEFAAKGIWKETIKPIVDKSLGGTLRLFVQKVYEGSYFTRNEETVLSISA
                     SMPNGTTLDQMNHLINRMEAYLSTYKEIRQFQTSIYNARQASINVYFTRENERSGFPY
                     TLKSRVISKALELGGGSWGVWGLMDQGFSNDVRENAGSFRIEMYGYNYDELYEWAEKL
                     REKLLTYRRIKEVLINSEFSWWKDDYQEFYFNLNKSRMAQADILPIDLFASIRPVFGK
                     DIYAGTIVVDNETEKLKLSSRQSKEFDIWSMQYVPQTIRDKSYKLSELAIVEKSQTPQ
                     QIAKVNQQYRLCLQYEYIGASSQGEKIQKRELREFNKILPMGYTAKAEKNYWSWDQKD
                     NKQYALLFLIIVIIFFTTSILFNSLKQPLAVIFVIPISYIGVFLTFYWFKLNFDQGGF
                     ASFVLLCGITVNASIYILNEYNQIRERIPAISPIRAYLKAWNAKITPIFLTVISTILG
                     FIPFMLGTDKEAFWFPLAAGTIGGLIMSILGIFFYLPIFTLKKERH"
     gene            complement(26968..28461)
                     /locus_tag="ACZPB4_08420"
     CDS             complement(26968..28461)
                     /locus_tag="ACZPB4_08420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HIR1098281.1"
                     /translation="MKKRYKRTFLVLYAFCSLLVGGVSAQSLVLSLEKTISLAADSSL
                     EAFRTKNLFLSGYWEFRNYKAERLPSLTLNITPAEYYRDITKRYDSEKDIDEYRKQQS
                     FYAGGNLKIKQNFDMLGGSFFVDTDLGYMRYFGSNTYNQFTSVPIRIGYSQDLLGYNP
                     FRWEKKIEPLKYEKVKKELLYNIETVSEQATTYFFSLAMAQVEYDMAKENVATTDTLY
                     RTGQERHKIAAISQADLLTLKLDAINARNTLQNADIALKRAMFSLASYLNFDKNTEIR
                     LRLPSRPHDMDIPVDQALTLARENNPKFLEVRQEVLEAEQQVDKTKKETLFNASLNAS
                     IGFNQVATQFKEVYKNPLQQDLVSISISIPLIDWGVRKGKYNIAKSNLNVTQISARQT
                     EVTLEEDVIMTVGDFNVQQNLIASAEEALDIAIMAYNETKQRFMIGKADINSLTLSLN
                     RQQEAQRNYITALQNYWLSYYKIRKLTLHDFETGISLANEFDYEHGF"
     gene            complement(28458..>29489)
                     /locus_tag="ACZPB4_08425"
     CDS             complement(28458..>29489)
                     /locus_tag="ACZPB4_08425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HIR1098282.1"
                     /translation="QAPDAPTLQKLEKTLESKTGLAPVGVAFENQLNISIDHQKLLLY
                     NISYEEVYRVLKTAFKENEVATLRSYQQYLPITLAGNEQTVDHILHNTLIRTQPDENQ
                     KTNHVPLSAVTKITPGEDLKTLTAGKNGEYIPFSFYQVENAEQLMENIRELVRSESKD
                     KTNWDIDFSGSFFSNQQMLNELVVILFISILLMYFILAAQFESFLQPLIVLLEIPIDV
                     AASLLVLWICGHTLNLMSAIGIVVTCGIIINDSILKLDAINELRKEGVPLMEAIHEAG
                     RRRLRPIIMTSLTTIFGMVPLLFTFDMGSELQKPLSIAMISAMLIGTAVSLFIIPLVY
                     WFIYRRHAL"
BASE COUNT         7907 a         6334 c         6647 g         8601 t
ORIGIN      
        1 gtggagaagg tacgtccgtc ggtcacccgt gaaggtacgc ctttgcaaat tatggaccgg
       61 gcgggaatcg atcgcttggg agtacaagac ctatccgagg ccgtgaaacg cttctcggga
      121 gttacggtac aggattatgg ggggatcgga ggattgaaaa cggtctcggt acgtagcttg
      181 ggagcgaagc ataccgccgt cagttacgat ggggtgacga ttacggacgc gcaaagcggg
      241 caagtcgata tcagccgttt ctcgttggat aatgtggaga tggtttcctt gtcaatcggg
      301 cagtcggatg acattttcca aacggcaagg gtgtatgctt cggcaggcgc cttgaatata
      361 caaaccggaa agcccacgtt taaagacaaa tcgtttcata cttatcttaa ggttaaggga
      421 ggttccttcg ggctttttaa tcctgtgctg cattatgatc aaaaattagg aaagcgttgg
      481 agcgcatcct tacatggtga tttcgtgcgt gcggatggac aatatcccta tacattaatt
      541 aatggggaat tggaaacgag agagaagcga agaaatagcg atatccattc tttccatttg
      601 gaaggtaatc tattcggcga ttttggaagg ggaggcgaac tttcctttaa ggcgtactat
      661 tttgattcgg agcgggggct tcccggttct gttaatttat ataacaagaa cacttctgaa
      721 cgattatggg ataataactt tttcgtgcaa tcggggtata agaatgttct taatgagaaa
      781 tttacgctac gggccatggc taagtataat tatgctttta ctcgttattt agatataaat
      841 gataaatatg ctgcgggcga acaagtcgat ttgaatacac agaatgagta ttatggctct
      901 gtaggtttgc tgtatactcc tataaagtat gtatcggcga cgttgactac ggatttaact
      961 cgctctatgc tggacaataa ttttgtgaac ggccctaatc caaagcgaat ggcctctcaa
     1021 tcagtactag cggtgcaata taagaacagt cgattcacgg ctaccgctag tttattggga
     1081 acatatatca ctgataaagt ggagcaaggg gaaaaaccgg atgataagag gcgtttatcc
     1141 ccggctgtaa gtttgtcttg gcggccattc tcggaaagta ctttgcggat acgtgcctct
     1201 tacaaagata tattccgggt tcctacattt acggacttgt attacctccg tatgggaaat
     1261 acaaatttga aaccggaaga aacttcccaa tataatgtag gggtaacatg gagttcttcc
     1321 tgtggggatt ggctgcggca tttcagtatt tcggcggatg gatattataa tacggtgaaa
     1381 gataagatcg tggctttacc taccatgtat gtttggaaga tgatgaatat gggcgaagtg
     1441 gatattaaag gggtagatgt aaatttatct acacaattcc gattgccctt acgaatgagc
     1501 ttgcttttgg cttccactta ttcttttcaa tacgcggttg atgtgacaga tccggaagct
     1561 aagaattata aggatcagat tccttataca cctcgtcatt ctggcacggt ttccgtaacc
     1621 ttggaaaatc catgggtaaa tgtctcttat atactgactg cggttggtga tcgttatgca
     1681 ttgccgcaaa atatagatcg gaacaggatt gattcttata tagaacagag tatttctata
     1741 aatcgagatt ttcgttttcg atatttcggt ttgcgtttgc aaggtgaatt gttaaatctt
     1801 gcgaacgtga attatgatgt tattcagtat tatcccatgc cgggccgttc ttggcgttta
     1861 agtatttgtt tatcctatta gtaaactata aaagtaaagt aatgaaaaag aagaatttag
     1921 tttgtgtctc tgccttgtgt gcattgatgt ctttctcgtt tgtcagctgt gatgatgaca
     1981 atgagccttc actgaacata ccaaatgtat ctgtaactaa tgtcagtttt acggatgaga
     2041 atccggaagc tttaaaagtt agcggaacct taaattggac agctccgtct tctgttgaca
     2101 atgtaacaaa gtacgtgatt tatggttcct ctgatggaac cgctaaagat atgaaaattg
     2161 cggaggtaga agttggaaca cattcatatg ctattacgga tgtcgtaaat ataggctatt
     2221 tattagttat agccgcaaat gcggaaggtg agtcttctgt ttatgcttcc gtaagagtta
     2281 ttgattttgt gaaggatagt tctttcatgg ctttatattt cttgaattcg ggcaatatgg
     2341 gaaataacaa ctcttcttta tatatgtacg acatagaaaa ggatgaggtt gtccccgatt
     2401 atttcttggc tcaaaatggc agggggctgg gagatacggc acaggatatg atcgtgtatg
     2461 gcgataagat gtatatcgcg gtatatggag agtctacgat agaagtgaca gatctgaagg
     2521 caaaatccat taagcaagtc aagacagagg ggcagccccg ttatatggta tcagagggtg
     2581 gaaaagtcta tattagctat tataatggat atgtcgctcg tttggatacc gcatccttgg
     2641 aggttgaggc gaaagtaaag gtcggacgga atccggaaca attggcggta tcttctaata
     2701 aattgtttgt ctcaaactcc ggaggtatgg attacagtac cgaggttggg tatgataaaa
     2761 cggtatcagt ggttgatctg tctactttta cagagataaa gaagttggat gtagtattga
     2821 atcccacacg gatacaggcg gatgagcaag gaaatgtata tgtggtttct atgggtaact
     2881 atgcggatat acccaatacg gtacaaaaga taaatacgga gacttatgag gttacttccc
     2941 ttacgaattg tccaaacgca acggagatgg cctatgagga tggcaagcta tttctgttct
     3001 atgcgcaatg gggaatgtct agccctgcat ttttaacatt tgatacaaag agccaatctg
     3061 cgggaacgag ctttattaca gatggaacct caatacaatc cccttattca atcagtgccg
     3121 tgggtggaaa tgtctatgtc gcagagtctg attataagaa taatggcgat atctattgtt
     3181 tcggaggtga cggtaaattg ttcaagaagt ttgaggccgg tttaaatccc atgaaagtag
     3241 tcctcgctca aaaagataat atctaatgcg attactgatt ctcttagggt tcgctttctg
     3301 gatggtggca tgtacgccat ccggaaagca aacttcttcc aaggaagctc tttcctctga
     3361 tagtattcaa tatgcccaag gtttcacggt tcagcgcttt gatacctata taatggtgga
     3421 agttcgtgat ccgtgggata gcacccgtct gcttcaacgc tatttattgg tagaccggac
     3481 aaagtcggtt cccggcggat tacccaaagg gacgatcgtg aaggtcccgg taaaagatat
     3541 tgtgatttat acttctgttc atgcggctat tattgatcaa ctgcacgaaa ccgataaggt
     3601 tataggcgtt tgtgagcctc gttatatgga tactcctgcc atacaagagg gtatacaggc
     3661 cggaagaatc gctgatttag gtgaggctac ctctccgaat atagagaaaa tgatagagat
     3721 cggcgcggaa ctcgtgatag cttccccatt ccagaacagt agttatgggc ctgtcgagaa
     3781 gatagggata cccattatcg aaggagccga ctatatggag gcatttcctt tggggcgcac
     3841 ggagtggatt cgcttttatg gtttgctatt cggaaaggaa gagatggccg attctatatt
     3901 taaagaaaca gagcaagcct atttgtctct aaaggactta accgcaaata tagataatcg
     3961 tcctactgtt ttgtcggaga aaaagttcgg ctcttcgtgg tatgtaccat ccggagatag
     4021 ttatatggct catcttatcg aggacgccgg agccgattat atgtttaagg atttaccggg
     4081 tgccggaagt acccccttag cgtttgagac cgtgtttgat aaagcgatcc atgcggatat
     4141 ttggcttgtt aaatataatc agtcttctga gatgacctat aacgatttac gctccgaata
     4201 tactccttac gagaatttcg acgcttttaa aaaaaaacgg atttatacct gtaatacagg
     4261 tgcagttcct tattacgagg aattccctat acatccggaa tatttattga aagatttaat
     4321 ctggattttc catccggagc tagtattcgg gtattctccc cgttatttta gagaaatgcc
     4381 ctgattgtct taaaggtttc atatctttgt tgaaatgtcg tttctagaca aataaaggta
     4441 ttagactatg aagataaaaa aggtatatgc tgatgcttta actacattag cgaagggaac
     4501 agatgccggg atttacaggt tgaatcccaa acgagttgaa atcgtgagtt gtgagcagga
     4561 tgtaaaacgt gttcttgctg aatgtgagaa gactggtaaa tctgtaacct ttaaagctgg
     4621 ggggacctct ttatccggcc agactattac agattctgta ttgatggaaa tcagtcctga
     4681 ctatggaaag gttaagattt caggagatgg gagtttggct aaattccctt gtggtataac
     4741 tggagaagag gcgaaccgct ggttgaaacc ttatggccgt aagctagggc ctagccctgc
     4801 ctccatcaaa tccgcacgta tcggcgggat cgtagcgaat aactcgagtg gttctagcta
     4861 tggtattatc cataactcct ataatacggt ccgggatatg gagattatct ttgcggatgg
     4921 agcctttttg gatacttctt cgttagcgag tcgcagggat ttcatgcaaa cgcatatagg
     4981 cttattggag aagttgatga atttccgttt ggagatcttg ttgaatccag acatggaaga
     5041 ccggattcta tctaaatatg agttgaagaa tacatgcggt tatggaatga actctttctt
     5101 ggattatacc gatccatacg atatactcat gcatttaatg gttggctcgg aaggaacctt
     5161 agggtttatt tcttcggtta ctttcgagac agtccccgat gaggctttaa aagcttccgc
     5221 cttgatttat ttcccctctt tgatggaggc gtgcagagcc atagccccgt tacgccaatg
     5281 caaagtgtcc gccgccgagt tgatggatag aaacgcctta catgcggtag aggatgaacc
     5341 ggggatgccg gagatattac attctttacc cgaggatgcg gtagcgttgc tgatcgacac
     5401 gtcttctaat tcggaagaag aacttcaaat ccaattccgg gatatagagg agcggctagc
     5461 agatatacag accttatatc cggtatcatt tacgaccgat ccgaagcttt acgctactta
     5521 ttggcgggta cgaaacggtt tatttacttc cgctgcggga agacggccac ggggtacggt
     5581 atctattatt gaagatatcg ctttccggga agaggtttta ggagaggctt tggaacaagt
     5641 gcgtggggtc ttgtcggatt atggatacgg aaatgcggtg atgtggggac atttattgga
     5701 tggaaacgtt catttcacga tttttccgga tataaacgca caggaaggta tcgatcatta
     5761 cgcttctttt atgcgtagcc ttgtagatgt ggtactttac tacgacggta gcttgaaagc
     5821 ggagcatggc acgggacgaa atatggctcc atttgttaaa gatgaatggg gtgaggagat
     5881 ttatgagttg atgtggaaga tcaaaaggct ctttgacccg gaaaatatat taaatccggg
     5941 tgtcctttta aatcgggacc cggatgtgtt tataaagaac ttaaagcaaa taccgttggc
     6001 gaatgagctg atcgataaat gcatcgagtg tggtttttgt gagatacaat gtccgtcaag
     6061 gcatgtgaca ttgacacccc ggcaacgtat cgtgatctat agggaattat cggctttggc
     6121 ggaacagggg gaaacaaact ctaagcgata taaagaactc aagaaagcct ttaactataa
     6181 aggtaacgct acctgcgcta ccgatggcct atgtgctacg gcatgtccgg ttggcattaa
     6241 taccggttta ttgatcaaag agttacggtg gaaagagaat ggtgtcttgg cgaatgctat
     6301 cgcttcgggc atcgccggga atatgggaac cgtaacgggt atgcttcgtc ctttgcttaa
     6361 gctgccccat gtgctttcaa agctggtggg gtataacgca ttcgagagat ttgcctcttt
     6421 cttgtttagg gcttccgctc ataaattccc gctttggact cggcatacac cttctggcgc
     6481 gtcaaagttc aaggaactga cgggtgtaga gaatgggatg gaaatggttt atttcccgtc
     6541 ttgtattacc cgtacgatgg gagcttcagc tgattatgaa gatgtggatt ttgtaagtgt
     6601 aacggaacaa ataatcgctt tattgacaag agcggacttt acgattcgtt atcctgagaa
     6661 tctaagtaag ctttgttgcg gcatggcttt tagcagtaaa gggttccgga agcaagcggc
     6721 gcagaaggcg gaggaattga atgaggctct tttgcgggcg agcgataacg gccgcttgcc
     6781 tattttgtgt gacatgagcc cttgcttgct gcatatgagg gaaaccttgg ataaacgttt
     6841 acgattatat gaacctgtgg agtttatcta tgactttatg cgtgatcgtc tgaactttac
     6901 taagttgccg gttacggtag cggtacactc tacttgtagt acaacgaaga tgggagtaca
     6961 agacaagctg gtggaactgg cgggcttatg cgcgaaccgg gtggtctctc ccgctcaagt
     7021 tacttgttgc ggttgggcgg gcgatcgtgg tttcttctat ccggaactaa acgcttccgg
     7081 tcttcattac ttgaaaccga atttgcatgg ggcgacggaa ggatatagca atagccgtac
     7141 gtgcgagatc ggtttgacga tgaatagtgg gatatcctat aaatcgatcg tctatttagt
     7201 ggaaaaggct actcgttaaa aatcaaaaac cccggtttcg tacaactgaa acccggggct
     7261 ttgtagtttg gcattcgaaa ttatagggag ttttatttca tagatttttt ttattcatat
     7321 tatgcgtaac cgttaagcat tccgttgaaa tacatcggtt ttaaaatata tacctttaag
     7381 atccaagcaa gccattgctc ttttgatgta tcgatcatcg agaatgggaa tgaaatgtct
     7441 ggtttctttt cgtagtcaaa ctcacaaagc aacacatgac cgtaatccgt gacgatcggg
     7501 caagcggcat aaccgttgta tttctcggtc ggctctttgc cttccatgag cgcgatcagg
     7561 ttcttggcgg cgataggtac ttgcttacgg atagcggcag atgttttact ggtcgggata
     7621 ccggctacat cacccagaga aacgatgttc tggtatttct tatgtaccaa ggtctcttta
     7681 tcgaccatta cccatgcgtc cgcggccaat ttaccttctg tccaacctaa tccggcatca
     7741 cgaacgaaat cgggagcgga cataggcggg gtgaagtgta agaaatcgta atcctctacg
     7801 aacggcgtta cgatcttttc ttcgcctttt gtctctattt tctcaaaatg cacttgtttt
     7861 gcggatgtgt ctacaccttt tacacgtaca ttcaagttaa taggtatgtt acgttcatta
     7921 tatatttcca gcaagcgagg cgtgaaatac ggaatatcgt atagctcctt cgatgcggta
     7981 aaataattca attgcagttt gtcgcgagtc ccttgtttcc ttgcgtaatg ctcggataat
     8041 aaacagatct ttttgggagc gccaccacat ttatgttttg tataggtatc ggtataaata
     8101 cctttgcctc cttttttagc gaattcttga agagctttcc atgtcttttg ggctccttcg
     8161 aaatcgtaaa tagagtttgc gtttccttgt cccaaggtgt cgtgggtaat gccctctact
     8221 ttttcccagt tacattgtaa tcccggggtc agtactaaaa agtcgtacgg aatctttccg
     8281 ttacttttgg tcgttacttg attccatacg ggatcaaccg cagcgaccga gtcctttatc
     8341 cattttatac cgctaggcat acaatcctct tgcttcttcc aaacatcttc cggttggtat
     8401 acacctgagg cgatcagagt gaatcccggt tgataaaact gacgatcgct ggggtcaatc
     8461 agggtgatat ccggttcatc aagccaatgt tttaatcggg cagccatact gataccagcg
     8521 gctcctccac cgataataac gattttacct tttgcgctgc ttgaaaaagc gtttgctttt
     8581 ccggtattag ctcccgcgat cagtcctgtc gccgctaata acttaaagaa atgccgtctg
     8641 tcgacacctt tcttttctag cgcatctaat tgtttctcca gttcgtgttt catcatgtcg
     8701 aaagaattta agattttatt cgctggcaaa ggaaacacaa taaattacgg tagccatgaa
     8761 aatgcctact acacgacttg cgcaaatgat ttttttattg gataagacta ctacaagact
     8821 ttctcaagct ccttttgtat atatatacta tgctgttata tagtatatta tatgtcaaat
     8881 agattaaaat tatataagac tcactttttg cgagattcta aagtgatgcg atccggaagc
     8941 cagagatacg ctggcacatc ctccaattcc aacacgattc tttcttcgat cattccttcc
     9001 gcttcctcaa agcttccgac gatgatcaaa tcctccttcc catcctcgtt aacagcctgc
     9061 ggcttaatat cgtacgatca accgcaataa gatctaccac atttttttta tctcttccag
     9121 ataaattaaa gtaagtcgtg ggagtggttt attgtgaata tgtaaatatt taacacataa
     9181 atctttatcc ataatgaata agaaaggagc gaaagaatct tctagttcca taggtagccc
     9241 taaattctta ttatgtaagc tcaatagttt tttcccatag caatcgtttc ttaatcgagc
     9301 aggataatca ggcgatacga aaactatttt tgtttttatt tcctcgtctg taaaaacctc
     9361 gttcattata tcgacaactg catcgataca aggaggacat gttttctctg aaaaacaaaa
     9421 gaataatttt ttatcattac ataaattact taaggagaaa gaatctagag agtctgttcc
     9481 ccaataggct atttgatcaa ggcattcata gtgttcattt tttagttctt ctcttttaag
     9541 gatacccaga ctttctttct cgtattcaaa attgtcaaca tacacatcct tcggggattt
     9601 tctaaaatga ttcacgcatt gcatacaaat tatgcctgcc agtatcccca aaaggaaaat
     9661 ataaattgta ttctcgttaa ccttcatttt tgaaaacata ttttactaag acaggattct
     9721 cttgttccga atgtgattga ataattcttt gctgatcctc atttcttaac ttctcgggaa
     9781 atagatcatt taatggaagc cctccttccg gagtacagag gatgaagtct tctccgaagt
     9841 agatcgggta aagttgcaag ccctccttgg ttcgctcgaa ttgaagcaag tcatggtttt
     9901 tcctgttata aaacagttgg atgtacttgt tttggcggac taccatggcg tatcgatatc
     9961 tgctgttttg tccctgagag tctattatat aatttacgct cttagaggaa tagacatcct
    10021 tcgcgtattg aattatttct tgcttgctca tattgggatg gaattctaat ttttcgatgt
    10081 cattatttaa atcaccaaaa tcccaacgat aaagctctgt aaaggtcgct cccgatagtg
    10141 aataaatcgt attagtcaaa gaccttcgaa aagcgtgtgg aaatggaaat acacccctac
    10201 aaaatacatc ttttatgtct tcaggaaaat attcatcgag tatctcgttt cttgataggg
    10261 aataaaactt caagcgatgg tcgtaatcgt atgtgaagaa agctatcgta tccttgtttt
    10321 ggaactgtag gctgttgtag gcccccgcta tttcaggaag tttctttttc tcgatgaact
    10381 tgccccctag atcatagaaa aagagagcgt tgctgacggc gcaaagtact acaaggttcc
    10441 tgcgggtcgt atcgatcgcg aaatctgtta agtttaaata ctcacccggg ccgtttcctt
    10501 tctcgttaag cgcgaattgg aaatgtccct ccctatcgaa aacaaagatt tgggatctcg
    10561 aataatcgtg aatataatat cgatcctcaa aaaacttgat ttgggttata ttacggatca
    10621 gcgattctgg cgttgtctct aacggaatga gttggatctc agaaaataga tctttagtgg
    10681 agatctcgtc tcgctcgtcc aaattcacgg tgatgatatc tgattccata tttttcttat
    10741 ccttccatcc cgtacaagaa agaaagaaaa atatggatat catcgaaaaa taatagatga
    10801 tacttttcat gctttttaat ctggataaca atgatgttct tgcattcctg agaaataaca
    10861 atgcacataa taaataccac ttatccaatc tacattccag caagtcccct catatctgcc
    10921 gcagcttatg actgggcctt ggtcgccatc cgggcaagca tgatcatcac tgtcaccttc
    10981 tgctaaaaca tctacgttta tagcgaaaaa gatcaaactg attaacgccg tgaatttaaa
    11041 aaatctcttt cccatacatc attaaattta agtgaaacaa aagtttgaat acaaatatat
    11101 atatattgat agtgtaatga tttccatgtg aaaatttccc ggaataaatt attcatgtta
    11161 gatgttgagt ttgtcgagag atcattttcg ggaagaattt tttacttcaa tacgatcttg
    11221 tagctttctt cccctccggt agccatgtgc aattggagga cgtataacca acccgtcggg
    11281 cgttctggtg agattctcgg aaaatatttt tagtagttca tcaggaaatc gacaagattc
    11341 gtatccccat caagggctaa tcgctttctt aagcggtatc ttcttagctc gatagcccgt
    11401 acggatacat tcattaacga tgcgatctcc ttcgtggaaa ggttcatgcg gagtaagcaa
    11461 caaatacgca aatcgcctgc cgttatatct gcgtattgct ggcgtaaacg atccatgaaa
    11521 ttctggtggg cgctattgaa ataggtctcg aactgcaccc aatccgcttg atcgttcaag
    11581 gtagattcga tcaaggaacg taaacgggta tataacttat tggggtatcg gtcacccaat
    11641 gtctctttct gcttatccag ttcttccaac aaagcttgga ttgcctcgtt tctttttacc
    11701 aaagctgttg tctggagagt aagctcattg tttttgtttt gcaactccgt ttccagcatc
    11761 tcgcttttca tttgttgaag cctttgcagt tcggcttgtc gctctgcctc cagcttttct
    11821 tgttcttttt tccgcaaatt ccttaaatgg taccgaagtc cttcttgaat ggcgaaccat
    11881 atcaaagcga cgtagatcaa ataggcccat acggtattat accaaggagg gcgcaccgtg
    11941 atttgcatcg tgatctcggg aaacggccca cgggttacat atttacgtac ccttagctca
    12001 taagttcctt ccggaagttg taagaaggta attttgccgt ctttctgcca agaagaccaa
    12061 tcggcggata ccccttccag cttataactg atttggtgat taggggtgaa taccgttgtt
    12121 ccgatgtata gcgagagttc ttggaagtta tggggcaggt cgattctttg cgtgtccgga
    12181 tataaataat gtgtaccttc ttgatcttga tactcgatgc gcataaaccg tggcatcgtc
    12241 aatcctccta ggcttccctc tattaattga cgagtgttga ttaatagggt tccttgcatg
    12301 gcagatacca aatcaagaga atcattcaag gggatgatcc gtttgccatt ggttaccaga
    12361 ttcagatcgt aattatcgaa taggatccgg cattttaaag ttcctgtacc gttttcccga
    12421 tggaagagtc cggcctcatt ctggatcgtg agccaataca aattgtctgg aaccgggtaa
    12481 atactttctg cgttggcgaa tacgctcaat acgtctttat tcttaaataa agagcttacc
    12541 gataaatgat tatcggtcgt atccggatgg atatatgaac gtccgatctc atcggatatc
    12601 ggggtaaact tatcaccaaa catcaggctc cggctgaagt agccgacatt ggtccggata
    12661 tagaggcggt tatcctcttt tacagcgtct tccaactttc cgatctggct tcttttacct
    12721 aacatggcga tgggaggatt gatatctatt tgggagatac cattatccaa ggcgacccag
    12781 attaaattat tatcctgtac gcagatggag cgtacgatat tatcttgtaa ctgattattg
    12841 atgttgagat gttgaaagat ctccccttcg tcgttggtga tataaatacc ggacgtagat
    12901 gttcccgtga aattgagacc tccggcgcta gcgaaggaag ttgggtgctt ctcctcgatt
    12961 tctttcggga tcgtgtaatt cgtctcggga tcatcgaaat ttatatatga cgggagcgta
    13021 tcgatcggat ggtattccag attcccgagt ttgtcgtata gccaatagcc taacgatgat
    13081 ttgccttggg tatagataga atcgttctgg aaagatactt tataaatagg ggttttatcc
    13141 ggtaatggat atgtgttcca tgtattcccg tcaaaagtaa ccagaccgga attattagct
    13201 acatataaga tgccatgata ggaaaccgct aaatcccaat tttggcaact agccttgtaa
    13261 tcgtctacgg aataattttg tacgaggata gagggagcga ccacagacgc acgcaaggcg
    13321 aaaaccgcca gtatagataa taatatgata aaaggtagcc gtctgtacat ggtctttaaa
    13381 ctatagagac aaggcataaa gccttgtctc tttctattac acgcatgcaa atataatcaa
    13441 attttgatta tttgtactcc tgccagctct taatctgaat atcttctacg ttcatattgc
    13501 agaaagcgtc gataaaggcg ctggccagac gggcgttcgt gatcaatgga atgttatgat
    13561 cgatcgccgc acggcggatc ttatagccat tggtcaactc acgtttgcta tgatctttcg
    13621 ggatatttac taccaattcg aaagcgtgat tgctgaacat atccatgatg ttcaaatcac
    13681 cttcctcatc cggccagcaa acggcggttg ccttgattcc attatcgttc aggaacttgg
    13741 cagttccgtg cgtaccatag atcgtgtaac ccttggcatc cagcatccgg caaggctcca
    13801 ataaatcgac cttgctctta gctgcgccgg aagaaactaa aatgttcttc ttaggaatac
    13861 tgttgcctac ggcgatcatg gcggaaagca aagcctcgtt gaaatcgtcg ccgatacaac
    13921 ctacctcgcc ggtggagctc atgtccacac ctaatacggg gtctgccttg tgcaaacggg
    13981 cgaatgagaa ctgggaagcc ttgataccga tccagtcgat atcgaacgcg ctcttatccg
    14041 gtttcgtata cggagcgtcc agcatgatgc gggtagccgt ctcgataaag ttgcgtttca
    14101 atactttaga tacaaacggg aaactacgtg aggcacgtaa gttacattcg attactttca
    14161 cgaagttatt cttcgccaag aactggatat tgaacggacc gctgatgttt aactccttcg
    14221 cgatcatctt gcttactttc ttgatacgac gggctgtctc gaagtaaatc ttctgagccg
    14281 ggaacaccaa ggtagcgtca ccggagtgaa caccggcgaa ctcgatatgc tcggagatcg
    14341 cgtactcaac cacctcgcca ttcatagcga cagcgtcgaa ctcgatctct ttcgttcctt
    14401 gcataaactc ggatacgacc accggatatt ccttggaaac cttagcggcc aaatccaaga
    14461 actcgatcat ctgctctttc gtatggcaaa cgttcatcgc cgcaccggac aatacgtaag
    14521 acggacggat caagatcggg aaacctactt tctcgataaa cgcgtcgatc tcttccatgc
    14581 tggtaagctc tgcccaacga ggttggtcga tacctagcga atccaacatc gcggagaatt
    14641 tatgacggtt ctcggcacgg tcgattgata gcggggaagt acccaatacc ggaacattct
    14701 ggcggtagag tttcatcgcc aagttgttcg ggatctgtcc acctacggag acgatcacgc
    14761 ccttcggcaa ttccagatcg atcacgtcta gcacgcgctc gaatgaaagc tcgtcgaagt
    14821 aaagacggtc gcacatatcg tagtcggtag atacggtctc cgggttatag ttaatcatga
    14881 tcgatttata acctagctta cgagcggtct gggcggcatt caccgaacac cagtcgaact
    14941 caacggacga gccgatacgg taagctccgg accccaagat aatcacgctc ttctcattcg
    15001 ggtagtaggt aatgtcgtgc ggcgtaccgt cgtaagtcat atatagatag ttggtcaatt
    15061 ccggatgttc ggaagcgatc gtgttgatac gtttcacggt agggagaatg cccattttct
    15121 tacgcaagtt gcgtacgcgg atattctctt tctccatatt gccttccggg ctctctacgt
    15181 aacgagcgat ctggaagtcc gagaaaccaa ggcgtttagc ctctttcaat acatcctccg
    15241 gaagatcctc gatcttgttg tagcctttca atacgttggc gtaatccacg atattcttca
    15301 agccttccaa gaaccagcgt gtgatctttg acaactcatg gatcttgtct acgctatatc
    15361 cttgttccaa ggcttgcgcc acggcgaaga tacgcaagtc ggtagggttc gccaactcct
    15421 cgtccaagtt atcgaagtgg atatcgttgt tacctacgaa accatgcatt ccttgtccga
    15481 tcatacgaag acccttctgc atgatctcct cgaagctctt accgatcgac atgatctcgc
    15541 cgacggattt catgctggaa ccgatctggc ggctgacacc cacgaacttc gtcaagtccc
    15601 aacgagggat cttcacgatc atataatcta cctccggcgc tttgtacgcg gagttcgggg
    15661 tacccatctc gccgatctcg tccaatccgt agcccaacgc caacttagcg gcgacgaaag
    15721 ccaatggata accgctggcc ttggatgcca aggcggaaga acggctcaag cgagcgttca
    15781 cctcgatcac gcggtaatcg caagtctcgg agttgaaagc gtattggata ttacattcac
    15841 ccacgatacc taagtggcgg atcgtcttgg tagaaagttc cttcaacagg tctaattctt
    15901 tctcggtcaa ggagcaagtc ggagccacta cgatactctc gccggtgtgt acgcctagcg
    15961 ggtcaacgtt ctccatgctc actaccgtga agcaatggtc gttcttgtcg cggatcacct
    16021 cgaactcgat ctctttccaa cccttcaaag attcctcgac caaaatctgg gatgagtaag
    16081 cgaaagcgct ttccgccaag gtgcgaagct cggcctcgtc cttgcagata ccactgccca
    16141 taccacctaa tgcgtaagcg gaacggatca ttacggggaa accgatcttg taagcggcag
    16201 ccacggcgtc gtccatgctt tctacggctt ggctgatcgg ggtcttcact tctatctcgt
    16261 tcagtttctt aacaaatagg tcacggtcct cggtgtacat gatcgcctca acggatgtac
    16321 ccaatacttt cacgccatat ttagccaacg tgccgctggt gtaaagttga gtaccgcagt
    16381 tcaaagcggt ctggccgcca aacgccaata ggattccgtc cggttgttct tttttgataa
    16441 cttcctcaac gaagtaagga gtgataggca agaaatatac cttatcggct actccctcgg
    16501 atgtttggat agtcgcgata ttcggattta gcaatacggt actgatccct tcttctttca
    16561 gagcctttaa cgcttgcgag ccagagtagt caaactcccc ggcctgtccg atcttcaggg
    16621 cacccgagcc cagaacaatc acctttttga tatcactttt cgacatagta atttgggttg
    16681 ttttgtttat tataatgatt ttagaatatt atacctttat attatatcac cggaccgctg
    16741 gacacaaaaa aaatgcgtta gtaaaagtaa ccaacgcatc ttatataacc aaattataat
    16801 cccgtaaaat agagaaaaga gcctcaacct ccgacatata accggaatag aacttcggat
    16861 tatccttatg tgtcttgttt gtcatctgct ctctcttcaa aatttcggca aaggtatgga
    16921 ttatgtctga aagaacaaag cttaaatgcg aaaatctatg ctgaaatagt attgtctgtg
    16981 tttaacagcc tctaaatcca gcttaacaca tccattattt aaaaacaatc ttatgtgttt
    17041 cataagtatc attgcctatt tggagtctta atacatagat gcccgaaggt aatgtattaa
    17101 aatctaagag atctccttct ctcaagaatg tcccctccct tactaatgct ccggttgatt
    17161 ggttatatag agtataggtt ggcctagtct ctaacataac actgaattga tcttggattt
    17221 gagtttcttt tgaaatatta accatatgag tggatgagga agttgaaaca gaataataat
    17281 atcccgtaac agatactgtt tttatcacat aagacccggg tgttccacaa gtgctggttg
    17341 aacgacagcc cacaatataa gttcctggtg cggagaaggt aacactgttt gaataccgat
    17401 aggcagacat gctagccgtg tttggactga ccatccattg ataattccct tcgtcttcca
    17461 taaatatagg gctagccgta aaagatgcac taccaccagc ccctacttga tccggaccgg
    17521 acacggaagt tatggatggg gcaccgatag aaacagtttt cgctacagaa actgaagagc
    17581 cattaggaag taccacattc gcataaatcg taccactcat tgttcctccc ggattagaga
    17641 tagcccgaac cgtgattgaa ttactattct gtcctccact tacaatttgt aggccactgg
    17701 ttcctaatgt ccaattcccc ttataattac gatttaacgt gtaggtttta tttccggtac
    17761 atggcactaa attatcgccg gatatttggg gatatacttc tcggacagcc gcctctgcat
    17821 caagcaaacc atatcccata ttggcattcc aagttccaaa tggatgtcct gaaactgttg
    17881 agtaagaata agatccaatt tttctggcag agtgtccaag tatatttcga acttcagctt
    17941 ctgtcaattt tggattaata gatagtagga gtgctgcaac gcctgaaact tgagggcaac
    18001 tcgctgaggt tcctccaaaa gtagagagat aatttccggg gtaaagcccg gcactcccca
    18061 ttaaatccaa tgtgcgaata tcccctgtat aatccaaggc accagaaggt gcaaccagat
    18121 taatttctga acctcttgca ctataagaac acaaagcacc atttttatca actgcgccaa
    18181 ctgcgataac cccattaaca gttgcgggaa acgaaacaga ggaaccagaa tttcctgctg
    18241 caaaaacaac tacacatccc agtccaccgc gtccattcgt tctagcatta tttatggctg
    18301 aggtaattgc atcagctaca gaaccacccc aagagttact aataacatct gcttcagcat
    18361 catcccacgc ataatttatc gcagctgcaa tattagaact agattgacta taaaatatat
    18421 taacagggac tattttcact agaggggcaa tccctgctat acctaaattg ttatgagaag
    18481 ctccaataat accagcgcag cattctccat gtggattatt tgagactggt gctccattcc
    18541 cattggctaa acccggcgta aaacccggca aaagtctatc acccagatcc tcatgccctg
    18601 ccacaccttg atcgataaca gccactttta tcgaagaact accttttgtc atactccagg
    18661 cttcaggagc attaatatcg atattccacg tcccacctaa ttgtcccgta ttatttaaat
    18721 aatattgttc gctataaaga gggtcattca gaaattgagt tattctcatt ataaagtcag
    18781 gatgacaaaa atcgaccaaa ccattctcat atattatatt ggcataagtt aaaacatcaa
    18841 acccttgatt cacggataat gtgtaaaccc catatttagt ttgatcaaca acttctacta
    18901 tctcattcat acctgctaat atagaatcaa tacttacgcc atttttaggc ttaagcagta
    18961 tatgattagt tacatataat gtatctgttc catttactaa ataagcagga gaagctcttt
    19021 tcactaaagg atccgactca tatgctttaa aatcattttc agaaaagata ttggatttat
    19081 tttcttttac aatgatgttc ggcgatattt cattaaatcc cttataatcc gaacttagca
    19141 ttggagttcg gattaaatcg gcttctatat tcaacacaag gtgtgatgag tctggggtta
    19201 aagcgatttt cctattttgt gaccaataat attgcgcatt aacatcgcaa tgtattgaag
    19261 acaaaagcac aatcactaaa agatatatca aattatttgt tttcattcca gttcgtattt
    19321 aattatttca acattttcag caatatacat agggactttg ttcgaaagat attcagagtt
    19381 tgggtcccgt gggtcataag attccgaagg gtgaggtatg gtaaaagcat ccaatatcac
    19441 accatctatg gctggatcat aagctctaca attgaatttt attgtatagg caagcttaac
    19501 tgtacgatta tcggggatat acagttgtat ggcattcgag aaattcaagc cggttacacc
    19561 aagcttcgga ccttcatgaa ttgctacaag acagatatta ttattttcga gcgcaatcat
    19621 gcttacaaag ccgaccagcc tatcatcttt atcacagctt atacatacta tgactaagaa
    19681 aaatgcaagt cctgttattt ttgtttttag tttttgcata tagttgaatt ttaagttaaa
    19741 caaatttatt ggatagtcat gtaactgatg aattaattga gagggaccgg ataagtgatt
    19801 ataccggttt ttttcatttt cgtttgctat attgcaatat agctatacga aaagcgacct
    19861 gtaagcagaa tgataaacgt tatctacgtt ctagtatgtg cgcaagttat caaaaaaaat
    19921 taagcgtgca agaaaaaaat agaatatttt aggtcctaga ttcaactaga agtgaatatt
    19981 cagaattata gtttcgccta acctgcctcg tgaaggatat aactttatct cactttttat
    20041 ttttatcttt gtgcgactaa tctgaaaaaa gaaagcttat ggcacggata acgattcctt
    20101 atgcggtagc ggatttcgta gatttacggg aacgtggtta ttattatgtg gataagaccg
    20161 atttcatccc gagcttggaa gattataacg ctcctgtttt cctccgtccc cggcgtttcg
    20221 gcaagagttt gcttatctct accttggcgt gttactatga ccgcaccaag gccgatcggt
    20281 tcgaggagct gttcggcagg acttggatcg gtgagcaccc gacggaggaa cataatcggt
    20341 atatggtcgt gcgctatgat ttctccaaga tggtgatggc tgatgacatg gaggggttgg
    20401 aacggaattt caatgacctg aattgttctg cggtggagat catggtgacg cataaccggg
    20461 acttgtttta aggacttccg gttctctagc cgtggtgatg cttccaagat gcttgaggaa
    20521 gctttggggt acgcccgcga gcatggattg ccaaaagtgt atgtgctgat cgatgagtac
    20581 gataatttca ccaatcagct attgacggcc tacaaggatc cgctctatga gcaggtaacc
    20641 acgaaggaca gtttcctgcg caccttcttc aaggtgatca aggcgggtat tggcgagggg
    20701 agtatccgta cctgtttctg cacgggggtt cttcccgtta cgatggatga cttgacaagc
    20761 ggatataata tagcggagat cctgatcttg gaaccggaat tcctgagtat gctgggcttc
    20821 acgtataagg aagcggaggt ctacttgcgt tacgtgctgg atacctatac ggaggggcag
    20881 gatcggttcg atgatgtttg gcaattgatc gtgaataatt acgatggtta tcgcttcttg
    20941 ccggaggccg aacccttgtt caattccacg atcctgacct atttcttcaa gaaattcacc
    21001 gttcgtaaag gtggaatccc tagtgagctg gtggatgaga acctgcgtac ggatatcggt
    21061 tggatccgtc atctgactct ttcccttgag aacgccaagg agatgcagga cgccttggtg
    21121 atcgatgatg agttgtccta taacgtttcc gacctgtcca gcaagttcaa caagaggaaa
    21181 ttcttcgaca agagcatcta tccggtcagc ctcttttatc tgggcatgac cacgctgcgg
    21241 agtaattacc gcatggtgct gcccaacctc acgatgcgca gcatctacat ggactattac
    21301 aacgagatga atcatatcga gggaaatgcc caacgctatg tccccactta cgagcgtttc
    21361 accgaggagc gtcgttttga gccgctggtg caaaactact tcgagcaata cctcggtcag
    21421 ttccctgcgc aggtgttcga caagatcaac gagaatttca tccgttgctc cttcttcgag
    21481 ctttgttccc gttacctgag cagctgctat acgttcgcca tcgagcagaa caattcggcg
    21541 ggacgttcca atttcgagat gaccggtatc cccggcacgg actattacaa ggacgaccgg
    21601 ttggcggaat tcaagtattt caaagcgaaa gaagcggagc gcatgctggc gctcagcgat
    21661 ccccgtcccg aggacgtggc gcaagtgctc gcctacgcca aggataccaa ggtgaagttc
    21721 ccacactatc atgtccgttc ctacattgta tatatctgtg ccaacaaagg atggaaatgc
    21781 agggaggtga ctccgtgata ttattccaat tgctttatta atagtacttt gtggtgccaa
    21841 tgatgtgcca tgctattggc acagttgtgc cacctcgatg gcaaaggcgt gccactgcga
    21901 tggcacatcc gtaacatggg taatggcaca agcctctctt ccttggttta ccagtcgtac
    21961 tcctcgaaat aagcgtcgaa gtcttttggt tccttcaccc cacagcgttt aagcgcattc
    22021 aatacgacct gttgctcgga gggtgagagc ggcctttctc ccttgcggac acggtagtaa
    22081 gtgcgccggc tgaagtgcct catgagtccc gggataacgg agagcatctg tttgtgtggc
    22141 aagctctcca ataggcttac gaatcccgcg gcatagcgta ctttcttgtt cggacggtaa
    22201 taagggcaag ttcccttcaa tgaggcgagg tgtctcctcg ttaaaggtga ttgtttgttt
    22261 cggcgttctg gaataggggt gtttacgcat acggcctgcc tcatgaattt acgaggtagg
    22321 ccgcgtaaaa atagctatta tcaagtactt atttaaccgt aacattccat ccggaaagaa
    22381 tacctccgta gaagtaaaag tctacgcaga atgtctttcc tgtgttcagc tctttgacct
    22441 cgtagtattt cgtggcacct ttttcgttca ccaatttata atcggcgata ttcggaatag
    22501 gcacgttggc gagttctttg atctttgcgt ttatcctatt caagatatcc atgctctcga
    22561 aaggattcgt tactttggtg ctcttggata aagccggatt caccccattg ttctcggcac
    22621 gaaccgcacg aacactatct gcataagcct tgaacatcgc acggctttcc ggagtgcgca
    22681 aagcggatac ggtaaagata gagattcctt ccgccccatg attcagtgcg gcatccatgg
    22741 cattctctat atcgtcggct accatcagtc cgcagtaaag cgtggttttc gggttcttat
    22801 cccggacatc ctctatcata cagtctgaga taaaactaat atcttccgtg tagaagttat
    22861 ggtataccat ggggaagaca atgtccagat tccatttccc ccagtcttga cgaaccattt
    22921 tggatgccat cttgggcgta gggaaaggag aggctgccat tttcttgccg taagagtgaa
    22981 ccacgtcggc gatcatatta gcgacctcgg taatctggtc acaacggaat tggagccatt
    23041 tctcgtcttg cgagggatct tcttgttctt ttggatcata tccgtaagcg gccttgaact
    23101 tctcgatcat ggccgggtga taaccaaaat cccattgcgg atattcttgg tcttgcacga
    23161 taccgtattt cggccaaagg gtagtcggca ggataacatc cacgaaacgg ttgtaatcga
    23221 tagcgatacc gttcaaaccc tctacctcgc agtaagcttc tattttcttc ttgataaact
    23281 cccgtacctc gggtaaggcg gggcacataa atttgtagta atccacgtaa gcggtcgtat
    23341 cggccaagct ttgtccattg cggtttacgc tgaaccattc gggatgttct tttaagatag
    23401 cgtctcggtc atgttccgga ttcatcgtcc ataaccaagc gtagacctct ataccatgtt
    23461 tctgggcgat gggaatagcg gcccgataat catccggagt aggggcgttt agcatgacac
    23521 cgtctatccc cgcctcattc atgatcgtac agatggagtc gaaattcatt ccgggctggt
    23581 aatccaacca agtccagaac atcggataag catctttcgt atcatttttc ggggaactgc
    23641 aagcacctac gcagcaagct accagaagca atactaaata atttatgtgt ctcataagtt
    23701 taatgaattt gattaacgat ttatccgtta aagatacgta ttcctgttta atgccgctct
    23761 tttttcagcg taaatatcgg taaataaaag aagatgccta ggatagacat gataaggccg
    23821 cctatcgttc cggcggcgag cgggaaccaa aaggcttctt tatcggtgcc tagcatgaac
    23881 gggataaatc cgagtatggt cgatataacg gttaggaaaa tcggtgtgat cttggcgttc
    23941 catgccttta gataagcacg gattggggaa atagcgggta tccgttcccg aatttggtta
    24001 tattcgttta agatatagat actggcgttt accgtgatac cgcataataa aacgaaggag
    24061 gcgaatccac cttggtcgaa gttcagtttg aaccaataga aggtcaggaa taccccgata
    24121 taagagatcg gtatgacaaa aataaccgcc agcggttgtt tcaaggaatt aaacaagata
    24181 ctggtcgtaa agaaaataat aacgatgatc aagaataata acgcatattg tttattatct
    24241 ttctgatccc atgaccaata gttcttttcc gctttagccg tatatcccat aggcaggatc
    24301 ttgttaaact ctctaagttc ccttttctgt atcttctcgc cttgtgagga ggctccgata
    24361 tattcatatt gcaggcagag cctgtattgc tggtttactt tcgctatctg ttgaggggtc
    24421 tggcttttct cgacgatagc gagttcggac aacttatagg atttatcacg gatggtttga
    24481 ggtacatatt gcatactcca gatatcgaac tcctttgatt ggcgagaaga aagttttagc
    24541 ttttccgtct cgttatcaac gacgatggta cctgcgtaga tatctttacc gaaaacaggc
    24601 cggatagacg cgaataaatc gataggcaat atatccgctt gcgccatacg ggatttattc
    24661 aagttgaagt agaattcctg ataatcatcc ttccaccaag aaaactcgga attgatcaat
    24721 acttccttga tacggcgata cgtaagcaat ttctcccgta gtttctccgc ccattcgtat
    24781 aactcgtcat aattatatcc gtacatctcg atccggaaag aacctgcgtt ctcacggaca
    24841 tcattgctga aaccttggtc cataagtccc catacgcccc aacttccacc acctaattcc
    24901 aacgctttgc taatcaccct gcttttcaag gtgtagggga aaccacttcg ctcgttctca
    24961 cgggtgaaat agacgttgat actggcttga cgtgcgttat agatactggt ctggaattgc
    25021 cgtatttcct tataggtact caagtaagcc tccattcggt tgatcaagtg gttcatttga
    25081 tcaagggtcg taccgttcgg catggaagcg ctgatactta ataccgtttc ttcattccgg
    25141 gtaaaataac ttccctcgta taccttttgg acaaataggc gcaaggttcc tcccaaactc
    25201 ttatcgacga taggttttat cgtttccttc caaatacctt tcgccgcgaa ttcattgtag
    25261 cgagcgatcc acaaagagtc ccttgcggat agatccttct cttccggctc gatcttctcc
    25321 ggcaataaaa atatcggtag tccgaaagcc agtactagaa taaggcaagc cagctttttc
    25381 caattgcaaa ggaaacggat ctgcgcccgg taataatgag agaaatagac tgggaaacgg
    25441 tgtatgaacg accgtatcgg acggaccacc ggatgttgtc tccaatgact ccgggctttt
    25501 ggggaagaag aagcgacttt cttccggtgc aaattcatct tgtcgatcaa tgccggaacc
    25561 aagaataacg cgatgaacaa agatacggcc agattaatga tcacgacagc agcgaaatcc
    25621 tgtaagttca accgtatctt ctcatccaag aagaagatga tcacgagggc gcccatagtc
    25681 gtcaaagtgg ccgccagaat agacaagaac gctttccggt catgatggtg ccggatatga
    25741 tcggtcatca cgatcgtatt atcgatcacc aagctgagag agatcgtgat acccgccagc
    25801 gagtacaatt gcatctccaa ccctaataaa taataaagga tgacggctat acacaggttg
    25861 atacttaaac tgatgatgat caagaacaga taacgtacat tccgggtaat cagcagaacg
    25921 aagagcaaga ggatcaagat ggtcaagcct gtacggacgt agattttatc caattcttct
    25981 tggataaatt cggtagcgtc gtaactggta tggatctcgt aaccgggagg aagcaaggtg
    26041 cggatatgtt tcatttcttc cttcactttc ttggctaatt gcaactggtt ggcagtctct
    26101 tccgcacgga tagacaggta aatagagttt aaaccattga tccggtagta actttgcggg
    26161 gcctcttctt gccgggttac ctttatcaat tgatccagcc ggattaagct accatctttg
    26221 tttgcgacgg tgatatgcga tggttcgaac ccattcgtga tcttttccgg cattaacgcc
    26281 agacgaatcc attccttgct ggtatctcct tgtcccatat tagcggttcc aaggaactct
    26341 tttttgtaat attggctgat cgccgattgg atatcctcta tcgtgatccc cagatcccgt
    26401 agctggcggc tatcgtattc caagcgccat tccatagggg tcgctccgct tacatcgata
    26461 cgataaatac cttgcacgct gctaagccgg ggctttatct gatcctcggc gaatcgctgg
    26521 atgaatatcg gggtagcgga agcgttcaag gtataactca tgaacgggcg tgattccttg
    26581 tcgtccggac ggctcatctc taaaatcgga taacttaatt cttccggaag gtccggccac
    26641 gtctgtctaa caattgttga tgcctcaaaa cgtgcggcat ctatattcgt atgtttatct
    26701 agttctaaag taatccttcc ccatccgttt cccgaggtcg aggagatctc tttgattcct
    26761 ttgatacggg caagcatcgc ctccaaccgt gaggttacct ccatctcgat aaccctcgct
    26821 gagttggagg gcatattata gctgatactt aatttcggca gcgtacggga gggagatagc
    26881 ttgatcggca ataaaggcac gaaagcgatc cccgccaatg cgatacaaag gaaggtgacg
    26941 atgatcgtaa aggatgatat gttcggctta gaacccatgc tcgtaatcaa attcgttggc
    27001 taatgagatg cctgtctcga aatcatgtaa ggtgagctta cgtattttgt aatagctcaa
    27061 ccaataattt tgcaaggccg tgatataatt acgttgcgct tcctgctgtc ggttcaagga
    27121 gagcgtaagg ctattgatat ccgctttgcc gatcatgaaa cgttgcttgg tctcgttata
    27181 ggccatgatc gcgatgtcca aagcctcttc ggcgctggcg atcaggtttt gctgtacatt
    27241 gaaatcgccg acagtcatga ttacgtcttc ctccagagtg acttccgtct gccgtgcgga
    27301 tatttgcgta acatttagat tgcttttggc tatattgtat ttacccttcc gtactcccca
    27361 gtctataagg ggaatagaga tagatatcga taccaagtcc tgctgcagcg gattcttgta
    27421 aacttcctta aactgggtcg ctacttgatt gaaaccgata ctagcattca aggaagcgtt
    27481 gaataaggtt tcctttttgg tcttatccac ttgttgctcg gcctctaaca cctcttgccg
    27541 cacttccaga aacttggggt tattctcccg ggctaacgtc aatgcttgat ccaccggaat
    27601 atccatatca tgggggcgtg acggcagacg aagccgtatc tccgtattct tatcgaaatt
    27661 caaatacgag gccagactga acatggctcg cttcaaggct atatcggcgt tttgtaacgt
    27721 attgcgggca ttgatcgcat ccagcttgag tgtcagtaaa tccgcttgac taatagccgc
    27781 gatcttatgc cgctcttggc cggtacggta taacgtatcg gttgtcgcta cattttcttt
    27841 ggccatatca tattctactt gagccatggc taaagagaaa aagtaagtgg tggcttgttc
    27901 gctgacggtc tcgatattat aaagcaactc tttctttact ttctcatatt ttagaggctc
    27961 tatcttcttc tcccaccgga aaggattgta tcccaataaa tcttggctgt atccgatacg
    28021 gattggaacg gaggtgaact gattataagt attcgagccg aaatagcgca tataccccag
    28081 atccgtgtcc acgaagaaac taccacccag catatcgaag ttctgtttga tctttaagtt
    28141 tcctcccgca taaaaggact gttgcttacg gtattcgtcg atgtcttttt ctgaatcgta
    28201 tcgtttcgtg atatcccggt aatattcggc gggtgtaata ttcaatgtaa gactaggcag
    28261 tcgctccgct ttgtaattac gaaactccca gtagccggac aagaataggt ttttcgtacg
    28321 aaaagcctcc agcgagctat cggcggccaa tgagatcgtc ttctcaaggg aaaggacgag
    28381 cgattgggcc gatactcctc cgactaatag cgaacagaac gcatataaaa ctaggaatgt
    28441 cctcttgtat ctttttttca taatgcatgt ctcctataga taaaccaata aaccaaaggg
    28501 ataataaata aactgacagc cgtaccgatc agcatcgccg agatcatggc aatggagagt
    28561 ggcttttgca actcacttcc catatcgaac gtgaatagta gcggtaccat accgaatata
    28621 gttgtcaatg aggtcatgat aatcgggcgc agacggcgac gacccgcctc atggatcgct
    28681 tccatcaagg gtacaccttc tttccgaagc tcattgatcg cgtccagttt caagatagag
    28741 tcgtttatga tgataccgca agttaccacg ataccgatag cactcatcag gtttaaggta
    28801 tgcccgcata tccataatac cagtaaggag gcggctacgt ctataggtat ttccagcagg
    28861 acgatcaagg gctgcaagaa gctctcgaat tgcgccgcta agataaagta catcaagagg
    28921 atggatatga acaagatgac taccaattca ttcagcattt gctggttcga gaagaagctt
    28981 cccgagaaat cgatgtccca attcgtctta tctttggatt cgctgcggac gagctcccga
    29041 atattttcca ttaactgttc cgcgttctct acttgataga agctaaaagg aatatattcc
    29101 ccgttctttc cagcggtgag tgtcttcaag tcttctccgg gagtaatctt tgttactgcg
    29161 ctaagaggga catgattcgt cttttggttt tcgtccggtt gcgtacggat taacgtatta
    29221 tgtaggatat gatcgaccgt ttgctcgttt ccggctagcg tgatcggtaa atactgttga
    29281 taagagcgta aggtagcgac ttcattttcc ttgaaggccg tcttaagtac ccggtagacc
    29341 tcttcatagg agatattata aagtaatagt ttctgatggt ctatggatat gtttaattga
    29401 ttctcgaaag ctacgccaac gggagcgaga ccggtcttac tctctagtgt tttctctagt
    29461 ttttgcaaag taggggcatc cggagcttg
//
LOCUS       DBMDTB010000042        29325 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_585_length_29325_cov_10.473583, whole genome shotgun sequence.
ACCESSION   DBMDTB010000042 DBMDTB010000000
VERSION     DBMDTB010000042.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 29325)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 29325)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29325
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_585_length_29325_cov_10.473583"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..749)
                     /locus_tag="ACZPB4_08430"
     CDS             complement(<1..749)
                     /locus_tag="ACZPB4_08430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010536568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohexomutase domain-containing protein"
                     /protein_id="HIR1098283.1"
                     /translation="MTLIKSISGIRGTIGGSPEDGLNPLAIVKFVAAYATFIRKNTKV
                     ETNKIVVGRDARISGPMVKQVVLGTLTGMGFDVVDIDLATTPTTELAVAMEGACGGII
                     LTASHNPKQWNALKLLNEKGEFLNAAEGAEVLRIAAAEDFEFADVDHLGKVIPNATYK
                     QKHIESVLNLDLVDVEAIKAANFRVAIDCVNSVGGIVIPDLLYALGVKEIFKLHCAPH
                     GNFSHNPEPIPENLTEISDLMGHAKADVGFVV"
     gene            complement(746..1318)
                     /locus_tag="ACZPB4_08435"
     CDS             complement(746..1318)
                     /locus_tag="ACZPB4_08435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4827 family protein"
                     /protein_id="HIR1098284.1"
                     /translation="MKKGFNILLILCVTLVAISCSKTKSYTDMLKDEKKAIERFIDDK
                     GLEILDDFPADSVFKENQFVLLDNGVYLNIIDKGSDQRAVQYKTKMLYRCKMSYFMDS
                     TIVAIENYGPHSNGTSPIAFTYGDYSKNSPYDPSYYYVSEGMQEPLKYVGDRAKVKMI
                     VPFKRGAYNDQSNGQPVYYEILEYIFEENL"
     gene            complement(1371..2420)
                     /locus_tag="ACZPB4_08440"
     CDS             complement(1371..2420)
                     /locus_tag="ACZPB4_08440"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HIR1098285.1"
                     /translation="MITKIIQEEKIQKAKKYVEKGESFVIVTHVSPDGDALGSSLGLY
                     HFLSAYGKDNVAVVVPNAFPSFYRWMPGAKDVVIHEKYPDFAEKLIKEADVIFCLDFN
                     EPKRIEKLAPAVIASEGRKVMIDHHLNPADFCRVTMSYPEMSSTSEMIFRFICRMGMF
                     DLLNRDAAACIYTGMMTDTGSFTYNSNKPEIYTIVSELIKKGIDKDLIYRKVNQVYSE
                     CRLRMMGYVLYEKMRVYPEQQAALITLSKEELDRFQYQAGDTEGFVNLPLSIENVSFS
                     VFIREDSDYIKVSLRSVGDFPCNQFASTYFNGGGHKNASGGEFYGSLSEAVAVFEKGL
                     QEFNPNKSEDLGKHA"
     gene            complement(2459..3745)
                     /locus_tag="ACZPB4_08445"
     CDS             complement(2459..3745)
                     /locus_tag="ACZPB4_08445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0030420 - establishment of competence for
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ComEC/Rec2 family competence protein"
                     /protein_id="HIR1098286.1"
                     /translation="MIEEIQKRPFVRPLFLWITGILCYAFLPASSLLYVLGVLSALVF
                     LFLGFSWGQGHAELQYDSRWIWGAIVSVLIVCLAVEVCWYSDRRIALVNEPASSLDLL
                     ATKAQYSLVNTFDRLRLSDEEKSILATLTLGYKKAMSRETKRRFSLAGVSHILAVSGF
                     HVAVICGFLSFFCSFMPRWGIGRWVRYIILVGSLWGFVFITGLAPSAVRAALMLSLYL
                     TGRALRRVTDGYNTLAAAAFCMLAYNPYYLFDVGFQLSYLAVFFILFLVPRFKEWIVV
                     RNPLLAMPWEWITVSIAAQIGTALLCFYYFGQFSTVFLFTNLPVTLLAMFLIPFAFLW
                     LGYPVDFYGYDWIQKIVEGLVHGMVRVVDVFSVMPYATITGRFSFFEMLGGYGFLVLC
                     LIYMKIREPKVLLAALTLLLIISVKILIELFLIAGN"
     gene            complement(3778..4428)
                     /gene="rpe"
                     /locus_tag="ACZPB4_08450"
     CDS             complement(3778..4428)
                     /gene="rpe"
                     /locus_tag="ACZPB4_08450"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HIR1098287.1"
                     /translation="MKHLIAPSLLSANFLDLRKEMEMINKSDADWLHLDIMDGVFVPN
                     ISFGFPVLNALKPICQKPMDVHLMIVEPQKFIPEVAATGAYMMNVHYEACSHLHRTVA
                     AIKETGMKAGVTLNPHTPICLLEDIIQDVDMVLLMSVNPGFGGQRFIEHSVDKVARLR
                     EMIDRKGLSTMIEVDGGVNLETGKRLVDAGANVLVAGNFVFKSPDPIQTIKDLKAL"
     gene            complement(4507..4680)
                     /locus_tag="ACZPB4_08455"
     CDS             complement(4507..4680)
                     /locus_tag="ACZPB4_08455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098288.1"
                     /translation="MRKLSTQCMDDLEKKVKSAPEAKSSPRKQTMDFLKQFARAYQAE
                     PAVRPELCGYVLN"
     gene            complement(4756..5349)
                     /locus_tag="ACZPB4_08460"
     CDS             complement(4756..5349)
                     /locus_tag="ACZPB4_08460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HIR1098289.1"
                     /translation="MKTLKMMTDEELVVLYAEGNNAAFDILLNRYKSSIHSYIYFIVR
                     NKELTEDIFQETFVKVIMTIKQGRYTENGKFKAWITRIAHNLIIDNFRQERCENTISN
                     DEVEIDLFNNIKLCDGTIEDNIVRHQVLSDVKKLVKHLPDNQREVLEMRYYQDLSFKE
                     IADITGVSINTALGRMRYAILNMRRMADENRIELSMV"
     gene            complement(5555..7165)
                     /locus_tag="ACZPB4_08465"
     CDS             complement(5555..7165)
                     /locus_tag="ACZPB4_08465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OmpP1/FadL family transporter"
                     /protein_id="HIR1098290.1"
                     /translation="MKRIGIIMSVLALCGGTAFSQSQLDAFKYSQTELNGTARYLGMG
                     GAFGALGGDISAMNTNPAGLAIYKSSEVVTTLSLSSASAKTDWLGSKVDNSRTKVSFD
                     NIAYVGYFPTANDEGIVSWNVGFSYNRLKNYSRNYTMATGGDLNTSLSDYVAMRAAGM
                     PSGLLGEDKDYNPYNNQDLGDWLSILGYNAGYMDSYNDNDKEYYSAFGDNNADGQWSP
                     YLLQGGQLKVSERGSVDQYDLAFGINISELVMLGATVAITDLNYRYQSSYDEEFTNGN
                     NLYLDNYLDTDGTGYSFNVGAIVRPADFLRLGVAYNSPTWYKMTDRYYGEAGSYLTFM
                     DKGEMKERKLDAATPNNAYYDYEFRSPDKWIFSAAAILGTTALISVDYELMNYKNMRM
                     YQTDGSSNVYTNQDITDNFKSMNTIRVGAEVKVTPQFAVRAGVAYSDSPIKDKLKNGE
                     KEVFTVGTIPNYTIDKGVMNYTVGIGYRFTPNFYTDLACVFRTHKEDVYAFSNMFAGD
                     DPKPFLEAQPATMKTNTTRVALTLGYKF"
     gene            complement(7196..8485)
                     /locus_tag="ACZPB4_08470"
     CDS             complement(7196..8485)
                     /locus_tag="ACZPB4_08470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098291.1"
                     /translation="MKPMKLTSLVMMLLIAFSAAAQEEFFDDVYFSSKNKKKKEQVEE
                     KKVVQPKQESRALVATAKSPASSDSRDVDEYNRRYTSVEVEEPYREDDSVIYEDSDEN
                     ESSSERRSDTEYTERIIRYHSPSKITIAGADQVDLYLSDGYYGYGYDTDYSNGSANVN
                     FNINVGNGWGSPWYTGWYDPWFYSYSPWWTYSSRFYGPSWGFGWGWGGFYAGYYSPWY
                     DPWYGPSWGWGGGYWGGHWGHHHHYYPGYYSTPSRHYSNGRSSYRDNRSYASGRGSGY
                     TGGRSSGSSSLRNSGSTTRPSSSSSLSNGRAGSTRRESAISSGAGRRSSSSVRNSATT
                     RSSSGISNSSARTRISRSSSGAASSSGRQYSAPVTRSSSRSSSDFSNSRSSSSQFRSS
                     SPSRSSSVGSSSGSFGGGRSSGGSVGGGGGRAGGGRR"
     gene            8773..10839
                     /locus_tag="ACZPB4_08475"
     CDS             8773..10839
                     /locus_tag="ACZPB4_08475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter domain-containing
                     protein"
                     /protein_id="HIR1098292.1"
                     /translation="MVLASTIDFTLPLADPVLKFLLILLIILAAPLLLNKLRIPHLLG
                     LIIAGAIIGPHGFNLVLRDSSIILSGTAGLLYIMFLAGLEIDMADFKRNSTKSLAFGM
                     YTFLIPMILGTVVGIWVLRFNVLTSVLLASMFASHTLIAYPIISKLGISKNKAVSITV
                     GGTMITDTLALLVLTIIVGMATGQVNDMFWIRLGVSILIFALIVLFGFPFIGRWFFKH
                     VHDNISQYIFVLVMVFLGSFLAQVAGMEAIIGAFLSGLALNRLIPQSSPLMNRVEFVG
                     NAIFIPFFLLGVGMLIDYRTFFTSFETIKVGLIMIIVATAAKYIAAWMTQKTFHLSTD
                     QRSVIFGLSNAQAAATLAAVMVGYNVITGTDANGEPIRLLNESVLNGTILMILVTCTI
                     ASFAAQKGAHNIAAQDISDKEENKKESEHILIPVSNEETVEELVNLSLAIKSPQNKNG
                     LFALKVIDNHHSDEKALKQSRRVLQTAVNTAAATDTRMKDLLRYDLSVSNAIASVVKE
                     REITDLVVGLHKEKDIPAAFLGHIVESVLAESSVSTFIYKPAQPISTVRRHLIIIPEL
                     AEKEIGFNQIIFRLRNVTQNTGAATVFYGSEATLNALKKLLAKKSGEASYIEFNDWDD
                     FLIVFRDIKPDDTMWIILSRKEGLSYAPAMARIPKYLNKYFQANSFVLAYPVQAGMNE
                     GTRYLT"
     gene            complement(10843..11838)
                     /locus_tag="ACZPB4_08480"
     CDS             complement(10843..11838)
                     /locus_tag="ACZPB4_08480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Acg family FMN-binding oxidoreductase"
                     /protein_id="HIR1098293.1"
                     /translation="METGSLRISDIRPDFIYMMEQAVKAPSGHNTQPWLFRVQKDRIQ
                     ILPDMSKSLPAVDPDNRELFISLGCATENLCIAAEAKGYTPLPFFSGSGEITVLLSEA
                     SMIKETSGLIEEISVRQTNRGIYSGEMIPSDQLSYLRNTPLEENISLHLWSKGEWEFD
                     TLSSYIFAGNNRQMNDRLFKRELKSWMRFNKNHVRATSDGLSYAVFGAPNLPRLISET
                     IMGSVLKAGIQNRGDKKKLDSSSHLALFALRINTLPEWFALGRSLQRFLLRATEKNIA
                     FAFLNQPCEVRDLSGLLAKDLSFTNEIPALILRLGYAKRKMPYSPRKSWRERLVP"
     gene            complement(11953..12037)
                     /locus_tag="ACZPB4_08485"
     tRNA            complement(11953..12037)
                     /locus_tag="ACZPB4_08485"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12001..12003),aa:Ser,seq:tga)
     gene            complement(12053..12125)
                     /locus_tag="ACZPB4_08490"
     tRNA            complement(12053..12125)
                     /locus_tag="ACZPB4_08490"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12090..12092),aa:Lys,seq:ctt)
     gene            complement(12145..12217)
                     /locus_tag="ACZPB4_08495"
     tRNA            complement(12145..12217)
                     /locus_tag="ACZPB4_08495"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12182..12184),aa:Lys,seq:ctt)
     gene            complement(12334..13137)
                     /locus_tag="ACZPB4_08500"
     CDS             complement(12334..13137)
                     /locus_tag="ACZPB4_08500"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010538067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HIR1098294.1"
                     /translation="MKLSFLSLASGSSGNCYYLGTSEFGMLIDAGIGIRTIKKVLKDR
                     SIDFTKIVAVLITHDHADHIKTVGYLGEKLCIPVYATADVHRGIDKSRYVEETLCVSR
                     KVIEKEVPFLIRDFRITAFEVPHDSTDNVGYHIEYGNHKFTFATDVGHITDTVGKYIC
                     MANHLILEANYDEEMLRFGTYPAFLKERVASPTGHLSNREAAEFLATHYNTGLKNIWL
                     CHLSRDNNHPELAYKTVDIRLFQEGIRVGKDVSLVALKRTTPSDIYEFD"
     gene            complement(13187..14251)
                     /locus_tag="ACZPB4_08505"
     CDS             complement(13187..14251)
                     /locus_tag="ACZPB4_08505"
                     /EC_number="3.5.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004067 - asparaginase activity [Evidence
                     IEA];
                     GO_process: GO:0006528 - asparagine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HIR1098295.1"
                     /translation="MDMHTQQEKASILLIYTGGTIGMIENPETGVLESFNFQHLKDNM
                     PELKKLGYSVATIQFDPPMDSSEMGPDSWMKIVKIIADNYQKYDGFVVLHGTDTMSYT
                     ASALSFMLENLSKPVILTGSQLPIGMLRTDGKENLITAIEIAAAKENGLPLVPEVCIF
                     FENDLLRGNRTSKINADNFNAFRSYNYPALAHAGIYIKYDLPQVYHPVSRKPLKPHYL
                     LDRNIAILKLFPGISPQVVESILNIPGLKGVVMETFGSGNAPCEEWFLNMLKEAVDRG
                     IVIVNVTQCRAGSVEMHRYETGHKLLEAGVTSGFDSTTESAVTKLMFLFGHGLTPDEV
                     KEHMNCSLIGEVSIPETFRP"
     gene            complement(14274..14885)
                     /locus_tag="ACZPB4_08510"
     CDS             complement(14274..14885)
                     /locus_tag="ACZPB4_08510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010799835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trimeric intracellular cation channel family
                     protein"
                     /protein_id="HIR1098296.1"
                     /translation="MIDFITFCDYTGTFAFAISGIRLASAKQFDWFGAYVVGVVTAVG
                     GGTIRDILLNAVPFWMEQASYLIVSALALLFVIAFRKYVIRLNNTFFIFDAIGLGLFV
                     VVGIAKTLDFGFPMWVAIVMGTITGSFGGMMRDILINEEPLIFRKDIYALACVFGGLI
                     YYICMQTSMSAAMIQFVSALSVFLARIIAVKYHISVPVLKGEE"
     gene            15059..16540
                     /locus_tag="ACZPB4_08515"
     CDS             15059..16540
                     /locus_tag="ACZPB4_08515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3943 domain-containing protein"
                     /protein_id="HIR1098297.1"
                     /translation="MRMKKCMLIGLICLLSSQWMWGQHFPQMDARNYVSDTALFIPRR
                     PWLAASEVFGMNMAVWTFDRFLMNEDFAKINGHTIKQNFKTGPVWDTDKFSTNLVAHP
                     YHGSLYFNAARSNGLNFWQSIPFAAGGSLMWEFFMETEPPSINDMLATSFGGIELGEI
                     TYRLSDLFIDNRSHGAERVGREILSGLISPMRAINRIITGEAWRHSSSKGRVYTSVPV
                     NFIVGVGPRFLAEQEGSKHGTTSMHVSFRLDYGDPFNDDFYSPYEWFQLKAGFDFFSS
                     QPLISQVNAVGAIWGKQVWSKGPRSLAAGIFQHFDYYDSELKSNSSQTVAPYRISEAA
                     AVGGGLIYYKRGTPDNKVDVYAELYGTGVALGASISDYLRLEERDYNLGSGYSVKAFT
                     GLAYDKRWAFLIDLENYHIFTWKGYEPDIDWNAVDPTKLNVQGDAGNARLTVFSTTLA
                     YMSKHKWNIALRNRYFSRRTHYKYHKDIDSSTYDIMLTLGWRI"
     gene            complement(16537..18174)
                     /locus_tag="ACZPB4_08520"
     CDS             complement(16537..18174)
                     /locus_tag="ACZPB4_08520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008157234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HIR1098298.1"
                     /translation="MISVDGLTVEFGGSALFSDVSFVINEKDRIALMGKNGAGKSTLL
                     KILAGVREPSRGKVSAPKDTVIAYLPQHLMTEDGRTVFEETAQAFAHLHEMEAEIAEL
                     NKQLETRTDYESDSYMELIERVSTLSEKFYSIEEINYDADIEKTLLGLGFKREDFDRQ
                     TSEFSGGWRMRIELAKLLLKKPDVLLLDEPTNHLDIESIQWLEDFLIDNGQAVVVISH
                     DRAFVDHITTRTIEVTMGRIYDYKVNYSQYLQLRKERREQQQKAYDEQQKMIAETREF
                     IERFKGTYSKTLQVQSRVKMLEKLEILEVDEEDTSALRLKFPPSPRSGSYPVTIENVS
                     KAYGDHTVFRNANLMIERGDKIAFVGKNGEGKSTLVKCIMKEIEHEGTLTLGHNVMIG
                     YFAQNQASLLDENLTVFQTIDDVAQGDIRNKIKDLLGAFMFGGENSAKKVKVLSGGER
                     TRLAMIKLLLEPVNLLILDEPTNHLDMKTKDILKQALLDFDGTLIVVSHDRDFLDGLV
                     SKVYEFGNQKVTEYLEGIYEFMQRKKMENLRELERKN"
     gene            18520..19068
                     /locus_tag="ACZPB4_08525"
     CDS             18520..19068
                     /locus_tag="ACZPB4_08525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HIR1098299.1"
                     /translation="MATKIRLQRHGRKGYAFYQIVIADSRAPRDGRFIERIGSYNPNT
                     NPATVDLNFERALYWLQVGAQPTDTTRNILSREGVCLKKHLLEGVKKGAFDEAAAEEK
                     FQAWLKNKQASVQAIKEKDSEAARAEAKARLEAEKEANKAKAEIVAKKKAELAAAEAA
                     KQAEEAAAAAPAEEAPATESAE"
     gene            complement(19151..19483)
                     /locus_tag="ACZPB4_08530"
     CDS             complement(19151..19483)
                     /locus_tag="ACZPB4_08530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CGGC domain-containing protein"
                     /protein_id="HIR1098300.1"
                     /translation="MKVGIIRCMQTEDFCPGTTDFRMIREKKGAFEGVEEDIEIIGFI
                     NCGGCPGKKAVLRARELVNRGADSIAFASCIQKGTPIGYACPFAKRMKDVIQNDLGDG
                     IRLIDYTH"
     gene            complement(19568..20041)
                     /gene="trxA"
                     /locus_tag="ACZPB4_08535"
     CDS             complement(19568..20041)
                     /gene="trxA"
                     /locus_tag="ACZPB4_08535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HIR1098301.1"
                     /translation="MRKLKSLWLVSVVLLLVSCSMSAKSDKSSEAGTASKGEVVTLNK
                     AEFLQKVFNYEKNATKWVYEGDKPCIIDFYADWCGPCKQVAPILRDLAILYKNDIVVY
                     KVNVDKEKELAAAFGIQSIPTFLFIPKEGQPQISMGALPREEFVKQIDTFLLKKK"
     gene            20234..20318
                     /locus_tag="ACZPB4_08540"
     tRNA            20234..20318
                     /locus_tag="ACZPB4_08540"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20268..20270,aa:Ser,seq:tga)
     gene            21460..21547
                     /locus_tag="ACZPB4_08545"
     tRNA            21460..21547
                     /locus_tag="ACZPB4_08545"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21494..21496,aa:Ser,seq:gga)
     gene            complement(21628..22503)
                     /locus_tag="ACZPB4_08550"
     CDS             complement(21628..22503)
                     /locus_tag="ACZPB4_08550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HIR1098302.1"
                     /translation="MKDAFIKLHISIILAGATGIFGKLISLNEALLVWYRMMLASLLF
                     LLVLSVSKRLNRISFGDALRIGGVGLLLGLHWVFFYGSIKASNVSIGVVCFSLVGFFT
                     AFLEPLINCHRVSFKEVVFSLLTLFGVVLIFHFDTRYRLGIGLGIISSALAALFTITN
                     KKIGNNYSTSTMLLYEMVGGFIGLSCILPFYLRYIPVSTIVPGLLDFTYLLLLASVCT
                     IGLYLLQIQVLKKISAFTVNLSYNLEPIYSIILAMLLFSEAKELNAAFYIGLGVIILS
                     VILQTLSVIRSNKKI"
     gene            22662..24011
                     /locus_tag="ACZPB4_08555"
     CDS             22662..24011
                     /locus_tag="ACZPB4_08555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HIR1098303.1"
                     /translation="MMQDSIDFGTMNIPKLFRMMFIPTLLGMVLSATINIADGIFVGR
                     GVGNDALAAVNIVAPFFMLATGIGLMFGVGASIVASIHLSHQKVKVANINITQALSVS
                     LCIMLSLSLLVMTFRAEVALLLGSSEQLLPSVLEYMNWIVPFLAFYMLLNIGLFIIRL
                     DGSPTYAMLCSAIPALINLTLDYIFVFPLHWGLMGAALASAISVIVGSIMIVVYIVGF
                     SKVLHLYRPKFSIKSILLTIRNIGYMVKLGSSAFLTEAAIACMMLVGNYIFMRYLGED
                     GVAAYSVACYCFPIVFMVNNAIAQSTQPIISYNYGIQQWKRVRQAFKLALLCAVVCGG
                     LACVGTILFCPEVSSLFLGNHGNAYEIAVSGIPYFSLGYVFFALNIVCIGYYQSIERF
                     KPATLFTILRGIVIITLSFMYLPVVCGIKGIWLAVPLSELITFVIIVVYYLLKRTRA"
     gene            24008..24598
                     /locus_tag="ACZPB4_08560"
     CDS             24008..24598
                     /locus_tag="ACZPB4_08560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HIR1098304.1"
                     /translation="MKEEVRQKVMERFSISEQAMQLLLESAEMMSFVPKDIIVHEGEI
                     NTNMYILSKGIWRAYTFKDGTEDTFWFAVESEIALPVWGYTSGSPSLYTIEAVTESEA
                     YCLSKQKLEILFQSSVQLANIGRRILENFMLEIETSWLSSYKRTAIERYAILLDKQPE
                     IIQSVPLKYIASYLGVTAQSLSRIRAKLASSLTFIV"
     gene            complement(24663..24957)
                     /locus_tag="ACZPB4_08565"
                     /pseudo
     CDS             complement(24663..24957)
                     /locus_tag="ACZPB4_08565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011202752.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(25195..26154)
                     /locus_tag="ACZPB4_08570"
     CDS             complement(25195..26154)
                     /locus_tag="ACZPB4_08570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098305.1"
                     /translation="MMINELNTGLIEALKEKLPPKTNLANLLMDTLYIGREAIYRRLR
                     GEVPFTLEEAALISRKLGVSLDKIVGVSFSANAVFDLNVVDHDDPFNAYFTILSRYVK
                     IFRAFQDDPTTALGTSSNTIPQILYLKHDLLSKFRLFKWMYQNKHIQCNHFENLKIPE
                     KLVDTQREFVSLTQYIHSTDYIWDNMIFHHLVNDIKYFSDIHLISCEDIQRIKEELLV
                     LVDELEELAMRGKTEAGNSVRIYVSHINFEATYSYLETSSLQLSMIRVYSINSITTQD
                     SEMFNSLKDWIQSLKKFSTMISESGEMQRIQFFNRQREIINTL"
     gene            complement(26242..26886)
                     /locus_tag="ACZPB4_08575"
     CDS             complement(26242..26886)
                     /locus_tag="ACZPB4_08575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HIR1098306.1"
                     /translation="MNLSLCPICGKLSEEEQTALFSSLDYSTRSFKKGDWVARQGDAL
                     SSLYLLSKGRVKTEMITESGTILEVETLSAPTPLASAFLFAENNRFPVDVIALEECEI
                     ILIPKNAVMRLLATNEHFLQSYMAFNANRTQFLSERLQLLSIKTIKGKLAYYILKRIQ
                     GDHYKQDRNQTELSEYFGVARPSLARSFSEMIEEGAISREGKIVDMNKLKSYVL"
     gene            27001..28647
                     /gene="hcp"
                     /locus_tag="ACZPB4_08580"
                     /gene_synonym="priS"
     CDS             27001..28647
                     /gene="hcp"
                     /locus_tag="ACZPB4_08580"
                     /gene_synonym="priS"
                     /EC_number="1.7.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016661 - oxidoreductase activity, acting
                     on other nitrogenous compounds as donors [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxylamine reductase"
                     /protein_id="HIR1098307.1"
                     /translation="MFCYQCQETAQGKGCILKGVCGKTAEVAGLQDLLMYLMKGISKL
                     TTTLRKRGVESATANKFIVDGLFMTITNANFDSSRFVSKIKEAYQLRENLLDELHRQG
                     IHPSLTCDCLTWKSDKVEEMEVKSKEVGILATENKDIRSLRELLTYGIKGMAAYVEHA
                     YNLGFEDTSLYAFIQDALVATTQSDLTVADLTRWVLTCGEYGVKAMALLDKANTSTYG
                     NPEITKVNIGVGKNPGILISGHDLRDIQDLLEQTEGTGIDVYTHSEMLPAHYYPAFKK
                     YKHFVGNYGSAWWKQTSDFETFNGVILFTTNCLVPPRSSATYADRVYTTGSTGFEGFP
                     HIADRKPGGSKDFSALIEHAKKCAPPTEIEHGEIIGGFAHEQVFQLADKVIDAVKSGA
                     IRKFFVMAGCDGRMKSRSYYTEFAEKLPKDTVILTAGCAKYRYNKLPLGEIRGIPRVL
                     DAGQCNDSYSLVMIALKLKEIFGLDDVNELPIAYNIAWYEQKAVIVLLALLYLGVKNI
                     HLGPTLPAFLSPNVAKVLVDNFGIAGIGSVDEDMELFLGK"
     gene            28703..>29325
                     /locus_tag="ACZPB4_08585"
     CDS             28703..>29325
                     /locus_tag="ACZPB4_08585"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008478 - pyridoxal kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009443 - pyridoxal 5'-phosphate salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HIR1098308.1"
                     /translation="MNKEQQKRVAAIHDLSGFGKCSLTVALPILSAAGIETSALPTAI
                     LSTHTGGILGYTYRDLTEDMRPFMKHWKELDIRFDAVYSGFLGSFEQLDIVKEFFSLF
                     KREDNLILVDPVMGDNGELYKIFTPKFAKGMRSLCEKADIIVPNLTEAALLLGEPYQA
                     GPYTKAYIDGILHKLSQLGPKQVVLTGVYFDEKELGAATFDMERNAT"
BASE COUNT         8619 a         7189 c         5699 g         7818 t
ORIGIN      
        1 actacgaaac cgacatccgc tttcgcatgt cccatcaaat cggagatctc tgtcaagttt
       61 tccggaatgg gttccggatt atgagagaag tttccatgag gggcgcaatg cagcttaaag
      121 atttccttca cacccaacgc atataacaaa tccgggatca cgataccgcc tacggagttc
      181 acgcaatcga tagctacacg gaagttagcg gccttaatag cctccacgtc cacgagatct
      241 agattcaaga cgctctcgat atgtttttgc ttataagtcg cattcgggat taccttgccc
      301 aaatgatcca cgtcggcgaa ctcgaagtcc tcggcggcag ctatgcgtaa tacctcagcc
      361 ccttcagcgg cattcaagaa ctcacctttc tcattcaaaa gcttcaaggc attccattgc
      421 ttcggattat gactggcggt aaggataata cctccgcaag ccccttccat agctacggcc
      481 aattcggtag taggagtcgt ggccagatcg atatccacca catcaaatcc catgccggta
      541 agcgttccta ggacgacttg tttaaccatc ggaccggaga tacgtgcgtc acgccctaca
      601 acgatcttat tggtctccac ttttgtgttt tttcggatga atgtagcata agcggctaca
      661 aacttaacaa tagctaacgg attcaatccg tcttccgggc taccgcctat tgtaccgcga
      721 ataccggaaa tagatttaat tagtgtcata agttttcttc aaatatatat tctagaattt
      781 cgtaatatac aggttgaccg tttgattgat cattataggc ccctcttttg aaaggcacta
      841 tcattttcac tttagcccga tctccaacat acttcaaagg ctcttgcatt ccctcactta
      901 cataataata agagggatca taaggtgagt tcttcgaata atccccatat gtaaaagcga
      961 taggagaagt tccattacta tgcgggccat agttctcaat agcgacaata gtagaatcca
     1021 tgaagtaact catcttacaa cggtacaaca ttttcgtttt atattgcacc gctctctgat
     1081 cgcttccctt atcaataata ttcaaataga caccattatc caagagcaca aactgatttt
     1141 ccttaaatac gctatcagca ggaaaatcat ccaaaatctc aaggccctta tcatcgataa
     1201 aacgctcgat tgcctttttc tcatctttca acatatccgt gtacgacttt gtcttgctac
     1261 aagagatagc gactaatgtg acacacagaa tcaacaggat attaaaacct ttcttcattt
     1321 gttagtcttt aattgaatga atcgcaaatg taaataatct tcgtcaaacc ttacgcatgt
     1381 ttgcctaaat cttctgattt attaggatta aattcctgta aacctttctc aaacacggct
     1441 acggcctcag ataaagagcc atagaactca cctccggacg catttttatg tccacccccg
     1501 ttgaaataag tagaggcaaa ctggttgcaa gggaaatcgc ccacagagcg aagcgatacc
     1561 tttatataat cgctgtcttc acgaataaag acactaaagc ttacgttctc tatgcttagc
     1621 ggcaagttca cgaagccttc cgtatctcct gcctggtact gaaaacgatc cagttcctct
     1681 ttcgataacg tgataagagc cgcctgttgt tccggataaa ccctcatctt ctcatacaac
     1741 acatatccca tcatacgtaa acggcactcg gaatagacct gattcacctt acgatagatc
     1801 aaatccttat caatcccctt cttgatcaat tcgctgacga tcgtataaat ctccggttta
     1861 ttcgaattat aggtgaacga tcccgtatcc gtcatcatac ccgtatagat acaagcggcg
     1921 gcatcccgat tcaataaatc gaacatcccc atacgacaaa taaaacggaa gatcatctca
     1981 ctggtagaag acatctccgg atacgacatc gtcacacggc aaaaatccgc ggggttcaaa
     2041 tgatgatcaa tcatcacctt gcggccttcc gaggcgatca ccgccggagc cagtttctcg
     2101 atacgtttgg gttcattgaa atcaaggcag aaaataacat ccgcttcctt gatcaatttc
     2161 tcggcgaaat ccggatattt ctcatgtatc acgacatcct tagcgcccgg catccatcta
     2221 taaaaagagg gaaatgcgtt cggtaccact accgctacat tatccttacc gtaagcggat
     2281 aggaaatgat ataaaccaag ggatgaacct aatgcgtcgc cgtctggtga gacatgcgtc
     2341 acgataacaa aactctcgcc tttctctacg tattttttgg ctttctgaat cttctcttct
     2401 tgaatgattt tagtgatcat ataatctttt tgttttcacc cccaaaggta cgactttttt
     2461 agtttccggc tatcaaaaaa agttcaataa ggatctttac tgatattatt aacaaaaggg
     2521 ttaaggcggc taacaaaact tttggttccc gtatcttcat atatatcaag cataaaacaa
     2581 gaaacccata acctcctagc atctcaaaga agctaaaacg acccgtaatc gtcgcataag
     2641 gcataacgct aaacacgtcc actaccctta ccatgccatg aaccagccct tctacgatct
     2701 tctgtatcca gtcatatcca tagaaatcca ccggatagcc taaccacaaa aaggcaaaag
     2761 gaatcaaaaa catagccaag agagtgaccg gtagattcgt aaacaagaaa actgtcgaaa
     2821 attgtccaaa ataataaaaa cagagcaaag cagtacctat ctgtgcagca atagacaccg
     2881 taatccattc ccaaggcatg gccaacaaag gatttctcac cactatccat tccttgaaac
     2941 gaggcactag gaataaaata aaaaacacag ccaaatagct taactgaaaa ccgacatcaa
     3001 acagataata cggattatag gccagcatac agaaagcggc ggcggccaat gtattatatc
     3061 catccgtaac acgcctaagc gcccttcctg ttaaatataa agatagcatc aaggctgccc
     3121 gtaccgccga gggcgctaat cctgtgataa agacaaaccc ccaaagactt cccaccagaa
     3181 tgatataacg aacccaacgt cctatccccc atcttggcat aaacgagcaa aagaaagata
     3241 agaatccaca aatcacggca acatgaaaac cgctcaccgc taatatatga gacacgcccg
     3301 ccaaagagaa gcgccttttc gtttcccgac tcatcgcttt cttatatccc aatgtcaatg
     3361 tagccaaaat agatttctcc tcatcagata aacgcaaacg atcaaatgta tttaccaaag
     3421 aatattgagc cttggtagcc aataaatcta aagaagaagc aggctcattt acaagcgcta
     3481 tacgccggtc actataccaa cagacctcaa ccgccaaaca tacaatcaaa acggagacta
     3541 tagctcccca tatccaacgg gaatcgtatt gcaactcagc atgcccttgc ccccacgaga
     3601 accccaaaaa aagaaaaacc aaagcagata aaacccctaa aacatatagg agcgaagagg
     3661 caggtaaaaa cgcatagcat aaaattccgg ttatccataa aaaaagcggc cgtacaaaag
     3721 gccgcttttg tatttcctca atcatgatag ttaggttttg tgatatatta atgtgttcta
     3781 caaagctttc aagtctttaa ttgtttgtat cggatctgga gatttgaata cgaagttacc
     3841 ggcgactaac acattggcac cggcgtcaac caagcgcttc cccgtctcta aattcacccc
     3901 gccatctacc tcgatcatag tactcaatcc cttccggtct atcatttctc gtaaacgagc
     3961 caccttatct acggaatgct caatgaaacg ttgaccacca aatcccggat tcacggacat
     4021 caataaaacc atgtccacat cttggataat atcttccaat aagcatatgg gcgtatgcgg
     4081 attcaaggtg acacccgctt tcatgcccgt ttccttaata gccgctaccg tccgatgcaa
     4141 atgggaacat gcctcataat gcacgttcat catataggct cccgtagccg ccacttcggg
     4201 gataaacttc tggggctcca cgatcatcaa gtgcacatcc atcggcttct ggcatatagg
     4261 ctttaatgcg ttaagtaccg ggaaaccaaa cgagatattc ggcacgaata ccccatccat
     4321 aatatccaga tgcaaccaat cggcgtcact tttatttatc atctccatct ccttccgcaa
     4381 atccagaaaa ttagcggaaa gcagggaagg cgctatcaaa tgcttcataa tcttgtcttt
     4441 tgtttttaca aaagtacaca aaaaaagaaa gagaacctaa taatatagat tctctttccg
     4501 taattcttag ttcaacacat acccgcagag ctccggacgt acagccggtt ccgcttgata
     4561 agccctcgca aactgtttca agaaatccat cgtttgcttc cgaggcgaac ttttcgcctc
     4621 cggggcactt ttcacttttt tctccaaatc atccatgcat tgcgtagaaa gcttcctcat
     4681 aggcacctct atttttatct tgtttgctaa taaaacgtag ggacctaaga cttattgcat
     4741 ggaaagaaaa ttattttaca ccatagatag ctcgatacgg ttctcatcgg ccatacggcg
     4801 catattcaag atagcgtaac gcatacgccc taaggccgta ttgatgctaa cccccgtgat
     4861 atcggcgatt tccttaaaac taaggtcttg atagtaacgc atctccaaca cttcacgctg
     4921 gttatccggc aaatgcttta ccaatttctt cacgtcagac aatacttgat ggcgcacgat
     4981 attatcctct atcgtaccat cgcaaagctt gatattatta aataagtcga tttctacctc
     5041 atcattcgag atcgtgtttt cgcaacgttc ttgacggaaa ttatcgataa tcaagttatg
     5101 ggcaatacga gtaatccatg ccttaaactt gccgttctca gtatagcgac cttgttttat
     5161 agtcatgata accttcacga aggtctcttg aaagatatcc tccgtaagct ctttgttacg
     5221 tactatgaaa taaatgtaag aatgaatgct acttttgtat cgatttaata aaatatcgaa
     5281 agcggcatta ttaccttctg cataaaggac aaccaattcc tcgtcggtca tcatttttaa
     5341 agtcttcatt actttcacat ttttagttta ttcgagtaat gtttatgcta taggcgatgg
     5401 ggtttaactg ttatacaatg ttatttatgg aagcaaaaga acgaaaaata ttttaaacca
     5461 acaaacattt tatttcaaat tataaaaaga atgtcccctg cccgcacctt taacgtacga
     5521 acaggggact ttactgatct aaaatatatg tatattagaa cttgtatccc aatgtcaaag
     5581 ctacacgagt cgtgtttgtt ttcatcgtgg cgggttgggc ttcgaggaat ggtttcggat
     5641 catctcccgc aaacatatta gagaacgcat aaacatcttc cttatgcgta cggaatacac
     5701 aagccaagtc cgtatagaag ttcggggtga agcgataacc gatacctacc gtataattca
     5761 tgaccccttt atcgatcgta taattaggaa tcgtaccaac cgtaaagacc tctttctctc
     5821 cattcttcag tttatccttg atcggactat cgctgtaggc gacacctgct cttacggcaa
     5881 attgaggagt aacctttacc tccgcaccta cacggatcgt attcattgac ttgaaattat
     5941 ccgttatatc ttggttagta tacacgttac tgctaccatc cgtttgatac atacgcatat
     6001 tcttataatt catcaactcg taatcaacgc ttatcaaagc ggtcgtaccc aagatagcgg
     6061 cggcactaaa gatccattta tccggagaac ggaattcata gtcataataa gcattattag
     6121 gggtagcggc atctagttta cgctctttca tctccccttt atccataaag gtcagataag
     6181 aaccggcctc accataataa cgatctgtca tcttatacca cgtaggtgaa ttataagcca
     6241 cacccaagcg aagaaaatcg gcgggacgga cgatagcacc cacattaaat gaatacccgg
     6301 taccatccgt atccaagtaa ttatctaagt ataaattatt gccgttcgta aattcctcat
     6361 catacgatga ctgatatcga tagttcagat ccgtaatcgc aaccgtagcg ccaagcatca
     6421 caagttccga tatatttata ccgaaagcca aatcatattg atccacggaa cctcgctctg
     6481 aaacttttaa ttgacctcct tgcaataaat atggactcca ttgcccatcc gcattattat
     6541 ctccgaacgc actataatac tctttatcat tatcgttata tgaatccata taaccggcat
     6601 tgtatcctag aatagatagc caatcaccca agtcttgatt gttataagga ttatagtcct
     6661 tatcctcccc taacagtccg ctaggcattc ctgccgcacg catggccaca taatcagaaa
     6721 gagaagtatt caaatcacct cctgtagcca tcgtatagtt ccggctataa ttcttcaagc
     6781 gattataaga gaaaccaacg ttccagctca cgataccctc atcattcgct gtcgggaaat
     6841 atcctacgta agcgatatta tcgaaactca ccttcgtacg gctgttatcc accttcgaac
     6901 caagccaatc ggtcttcgcc gaggccgaag acaaactcaa tgtcgtaacc acctccgagc
     6961 ttttataaat cgccaagcct gccgggttcg tattcatagc ggaaatatca ccacctaacg
     7021 caccaaaagc accacccatt cctaaataac gagccgtacc attcaactcc gtctgggaat
     7081 acttaaaggc atccaactgt gactgcgaaa aagcggtgcc gccacacagg gcaagcaccg
     7141 acattataat tcctatcctt ttcatcgtat ctctaatttt atcaacctaa cacttttacc
     7201 tgcgaccacc accggcacgg ccacctccgc caccaacaga gcctccacta gaacgacctc
     7261 caccgaagct accggaagaa gaacctaccg aactactacg agaaggagag gaacttctaa
     7321 attgactgga agaagagcga ctatttgaga aatcgctact gctcctagaa gaggaacgtg
     7381 ttaccggagc tgaatattga cgtccggaag aagatgcggc tccagaacta cttctggaaa
     7441 tccttgttct cgccgagcta ttacttatgc ccgagctact tcttgtcgtt gccgaatttc
     7501 taacagaaga agaggaacga cgtcccgcac cagaggatat agcagattcc ctacgggtag
     7561 atcccgcacg tccattgctc aatgaacttg aagacgaagg tcttgtagtc gatcctgaat
     7621 ttctcaagga agaagagcca ctgctccgcc cacctgtata accggaacct ctgccactcg
     7681 cataagagcg attatctcga taagaggaac gtccgtttga ataatgtcta cttggagtcg
     7741 agtagtaacc gggatagtaa tggtgatgat gtccccaatg gccaccccaa tagcctccac
     7801 cccagcccca agacgggcca taccatggat cgtaccacgg actataatag ccggcataaa
     7861 agcctcccca gccccagccg aatccccaag acgggccgta gaagcgagat gaataagtcc
     7921 accaagggct atagctatag aaccaaggat cgtaccaacc tgtataccaa ggcgagcccc
     7981 agccgttgcc gacattgata ttaaaattca cgttcgcact accgttcgaa taatccgtat
     8041 catagccgta accataatat ccgtcactca gatacaaatc gacttgatcc gctccggcga
     8101 tcgtaatctt actcggcgaa tgataacgaa tgatacgttc cgtatattca gtatccgaac
     8161 gacgctcgga agaagactca ttctcatcgc tatcctcata gataacggaa tcatcctcac
     8221 gataaggctc ctctacctcg actgatgtat aacgacggtt atattcatcc acatcccggc
     8281 tgtctgaaga agctgggctc ttggctgtag cgaccagggc cctagactcc tgtttcggct
     8341 gaacaacctt tttctcttca acctgttctt tctttttctt gtttttggaa gagaaataca
     8401 catcatcaaa gaactcctcc tgagccgcag cactaaacgc gatcagaagc atcatcacta
     8461 aagatgttaa tttcatgggt ttcatatttg tttctcctct acattaaata aatatttttc
     8521 tcttttcatg tttgacaccc ttttatgcaa agggtttaaa cgctttttag ttttataaca
     8581 ataaactcaa tgcaatgtat gtacaaatat aatcggttca cgctaatgtc ccaagattta
     8641 catatacttt aacttataaa actcacacat tcattgttat ctataaaaga agatgcaaag
     8701 ttggcgtaaa cgctgcaatc tccgcaaatt cttattattt ttgtttcaaa ttataacgaa
     8761 aaaattacgc atatggtatt agcctcgaca atagatttca cattgccctt agcggacccg
     8821 gtattaaaat ttctcttgat tcttttaatt atcctggccg ctcccctttt attaaacaag
     8881 ctgagaatcc ctcacctgct tggactgatc attgccggcg caattatcgg accgcacggc
     8941 tttaatctcg tattacggga tagcagcatt atcttgtccg ggacggcggg attgctttat
     9001 atcatgtttc tcgccggatt ggaaatcgat atggcggatt ttaagagaaa tagtacgaaa
     9061 agcctagcat tcggcatgta cacattcctc attccgatga tcctaggaac ggttgtcgga
     9121 atatgggtcc tgcgattcaa cgtattgacc tccgttttac tcgccagtat gttcgcctcc
     9181 catacattga tcgcctatcc gattatcagc aaactgggta tcagcaaaaa caaagctgtc
     9241 agtatcaccg taggaggaac gatgatcact gataccttgg cattgctcgt cctaacgatc
     9301 attgtcggca tggccaccgg acaggtcaac gatatgtttt ggattcgtct gggggtttcc
     9361 atcttgatat tcgcgttaat cgtattattc ggtttccctt tcattgggcg ttggttcttt
     9421 aagcatgtac acgataatat atcacagtat atattcgtgc tggtgatggt atttctggga
     9481 tctttcctag ctcaggtagc gggtatggag gcgatcatcg gggcgttctt atccggacta
     9541 gccctaaatc gccttatccc gcaaagctca cccttgatga atcgtgtcga gttcgtagga
     9601 aatgccatat tcatcccatt cttcttgttg ggcgtaggta tgttaataga ttatcgtacg
     9661 ttctttacca gtttcgagac cattaaagta gggcttatca tgattatcgt agctacggcc
     9721 gccaaataca tagccgcttg gatgacccaa aagactttcc atctgtccac agatcagcga
     9781 agcgttattt tcggcttaag taacgcacaa gccgccgcta cattggccgc cgtgatggtc
     9841 ggatataacg taatcaccgg aacagacgct aatggggaac caatccggtt attaaatgag
     9901 agcgtgttga acggtacgat cctgatgata cttgtcactt gtaccatcgc ctctttcgcc
     9961 gcccaaaaag gcgctcataa catagcggcc caagatatat ccgataagga ggaaaacaaa
    10021 aaagaatcag agcatatctt gataccggtc agcaatgaag agaccgtgga agagctggtc
    10081 aacctcagct tggcgatcaa atctccccaa aacaagaacg gcttgtttgc cctaaaagtg
    10141 atagataacc atcattcaga cgagaaagcg ttaaaacaat cccgcagggt tctacagacc
    10201 gcagtcaata cggctgccgc cacggatacc cggatgaaag atttattaag atatgactta
    10261 agcgtatcga atgctatcgc cagcgtggta aaagagcggg agatcacaga tctggtagtg
    10321 ggattgcaca aggaaaaaga tataccggcg gccttcctag gccatatcgt ggaaagtgta
    10381 ttggcggaaa gtagtgtaag tacattcata tacaagcccg cacaacccat ctctaccgtt
    10441 agacggcatc tgatcatcat cccggaattg gccgaaaaag aaatcggttt caaccaaatc
    10501 atcttccggt tacgaaacgt gacccagaac acaggtgcag cgacagtctt ttacggttcg
    10561 gaagcgacct tgaatgcctt aaagaaatta ttagccaaga aaagcggaga agccagttat
    10621 atcgaattca acgactggga tgacttcctg atcgttttcc gggatataaa accggacgac
    10681 acgatgtgga ttatccttag ccgcaaggaa ggactttcct acgctcccgc catggcccgt
    10741 atccccaagt acctcaacaa atacttccag gcaaacagtt tcgtattggc atatcccgtg
    10801 caggctggca tgaacgaggg tactcgctat ctgacttaac cattacggaa ccagcctctc
    10861 acgccaagac tttcgaggtg agtacggcat tttccgcttg gcgtatccca gacggaggat
    10921 caaggctgga atctcgttgg tgaaagacaa gtctttcgcc agcaaaccgg aaagatcacg
    10981 cacctcacaa ggctggttca aaaaggcgaa agcgatattc ttttccgtag ctctcaaaag
    11041 aaaacgttgc aaactccggc ctagcgcaaa ccattccggt agcgtattta tccgtaaggc
    11101 gaacaaggct aaatgagaag aagagtccag cttcttcttg tctcccctat tttgtatgcc
    11161 ggctttcaag acacttccca tgattgtctc tgagataaga cggggaaggt tcggcgcccc
    11221 gaacaccgca taactcaggc cgtccgatgt agctcgtaca tgattcttat taaaacgcat
    11281 ccatgatttc agctctcgct taaacagacg atcgttcatt tgccggttat tccccgcaaa
    11341 tatataagaa gaaagcgtat cgaactccca ctctcctttc gaccacaaat gcagactgat
    11401 attttcctcc aaaggcgtat tcctcaaata gctcagttga tccgatggaa tcatttcccc
    11461 ggaatatatg cctcgattcg tctgtctcac cgaaatttcc tcgataagcc cactcgtctc
    11521 cttaatcatc gatgcctccg acaagagtac ggtgatctcc cccgatcctg aaaaaaacgg
    11581 tagcggagta tatccttttg cctcagccgc aatgcaaaga ttctcggtgg cgcatcctaa
    11641 gctaataaat aactcacggt tatccggatc tacggccgga agggacttac tcatatccgg
    11701 aagaatctgt atcctatcct tttgcacacg aaacaaccaa ggttgggtat tatgccccga
    11761 tggggctttc acggcttgtt ccatcatata gataaaatcc ggccgtatat cacttatccg
    11821 caatgatcct gtttccatat tattatacac tttctcattc tagcgatgcc cgctacctct
    11881 ttccgtttgt gcccggacaa acgcctcaaa aacaaaaaat cccgtaaagc tttcgcctta
    11941 caggactctc tgcggaaaga cagggattcg aaccccggga acctctcagt tcaacggttt
    12001 tcaagaccgc cgcaatcgac cactctgcca tctttccaat aagtaaatcg tgtgacctgg
    12061 gaggggctcg aaccctcgac ccaatgatta agagtcattt gctctaccag ctgagctacc
    12121 aagtcaacat gttatttgtt tgagtgacct gggaggggct cgaaccctcg acccaatgat
    12181 taagagtcat ttgctctacc aactgagcta ccaagtcatt ctgtttcgct atcgttactt
    12241 tttcaaacca ccgtttgttt ctcgattgcg ggtgcaaaga tagaggtttt atttttcccc
    12301 gcaaactttt cgactacttt ttttcttaaa attttaatca aactcgtaaa tatccgaggg
    12361 tgtagtccgc ttcaacgcta ccaatgagac atctttccct acccttatgc cctcttggaa
    12421 aagacgtata tccactgtct tataggccag ttcgggatgg ttattgtccc ggctgagatg
    12481 gcaaagccag atattcttca aaccggtatt ataatgggtc gccaagaact ctgcggcctc
    12541 cctattactc aaatgcccgg tggggctcgc cacccgctct ttcaagaaag cgggatatgt
    12601 accgaaacga agcatctcct cgtcatagtt cgcttccaat attaaatggt tcgccatgca
    12661 gatatatttc cccaccgtgt ccgtgatatg gcctacgtcg gtagcgaaag tgaatttatg
    12721 attaccatac tcgatatggt accccacatt atcagtacta tcgtgaggca cctcgaaagc
    12781 cgtgatacgg aaatcacgga taaggaatgg aacttctttt tctataacct tgcgggagac
    12841 acataaggtc tcctccacat accggctctt atcaatcccc cggtgcacgt cggctgtcgc
    12901 atagacagga atgcaaagct tctcgcccaa atacccgacc gtcttgatat gatccgcatg
    12961 atcgtgggta atcaacacgg ccacgatctt ggtaaaatcg atcgaccggt ccttcaatac
    13021 tttctttatg gtccggattc cgatacctgc gtcaatcagc ataccgaatt ccgaagtccc
    13081 caaataatag cagttcccac tgctcccact cgctaaactc agaaatgata gtttcatact
    13141 ctcctattcc gcaacactgc tttttttctg ttttacatag tatacactag gggcggaacg
    13201 tctcagggat cgatacctcc ccgattaacg agcagttcat atgctccttc acctcgtcgg
    13261 gtgtcagccc atggccgaag aggaacatta gcttcgttac ggcgctctcc gtcgtactat
    13321 cgaagccgct cgtcacgcct gcctccaaca atttgtgccc cgtctcataa cggtgcatct
    13381 ccacacttcc ggccctacac tgagtaacat tcacgataac gataccacgg tctacagcct
    13441 ccttcaacat attcaagaac cattcctcgc acggagcgtt tccgcttccg aatgtttcca
    13501 tcaccacgcc tttcagaccc gggatattca ggatactttc cactacttgc ggagaaattc
    13561 cggggaatag ttttagtata gcgatatttc ggtccaacaa ataatgcggc ttcagcggct
    13621 tacgcgatac cggatgatat acctgcggca gatcatactt aatatagata cccgcatgag
    13681 ccaaagccgg gtaattgtac gaacggaacg cattaaaatt atctgcgttt atcttactcg
    13741 tacgattccc cctcaataaa tcattctcaa aaaagataca gacctccggg accaacggta
    13801 agccgttctc cttggcggcc gctatctcga tcgccgtaat caagttctcc ttcccatcgg
    13861 tacgcaacat cccgatcggt aattgcgatc ccgtaaggat caccggctta ctcaggttct
    13921 cgagcataaa actcaatgcc gatgccgtat acgacattgt atccgtgcca tgcagtacca
    13981 caaagccgtc gtatttctga taattatcgg cgatgatttt cacgatcttc atccacgagt
    14041 ccggccccat ctccgaggag tccatcggag gatcgaactg tatcgtggcc accgaatacc
    14101 ccagtttctt caactccggc atattgtcct tcaaatgctg gaaattaaac gactctaaca
    14161 ctccagtctc cggattctcg atcataccta tcgtcccacc cgtatatatc aacaggatgg
    14221 aagccttttc ttgttgagta tgcatgtcca tataattatg caaagttaat aaattattct
    14281 tctcctttca acaccggaac acttatatga tattttacgg cgattatacg tgcgaggaac
    14341 acgctcaacg ccgatacgaa ctgtatcatc gccgccgaca tagaagtttg catacatata
    14401 taatatatca aaccgccaaa gacacaagcc aacgcataaa tatctttccg gaatatcaaa
    14461 ggctcctcat taatcaatat atccctcatc ataccgccaa acgagccggt tatagttccc
    14521 atcacgatcg ccacccacat gggaaacccg aaatccaagg tcttggcgat acctaccacc
    14581 acaaacaacc ccaatccgat agcatcgaat ataaaaaatg tattgttcaa acggatcacg
    14641 tattttcgga aagcgataac gaacaacaaa gccaaggccg agacaatcaa ataagaggct
    14701 tgttccatcc aaaaaggcac cgcattcaat aaaatatcac gaatcgtacc tcctcctaca
    14761 gcggtcacga cacccaccac ataggcgcca aaccaatcaa attgtttcgc agaagccaat
    14821 cttatgccac ttatggcaaa cgcaaaggtc cctgtatagt cacaaaaggt gataaaatct
    14881 atcattttgt tttttttcgc aaaaatacgg aatagttcgc aaataacagc atttatagaa
    14941 agaataccta acaataattt aaaccaaacg aatcccttaa tgtttattat atataagttt
    15001 gcggagtggt tataaccgta acctattgat ttttatttac aaaagagaat tgagttagat
    15061 gaggatgaaa aaatgcatgt tgatcgggtt gatctgtctg ctatccagcc aatggatgtg
    15121 ggggcaacac ttccctcaga tggatgcccg caattacgtg agcgacacgg cccttttcat
    15181 tccacgccgc ccttggttgg cagcaagcga ggtattcgga atgaacatgg ccgtctggac
    15241 tttcgaccgt ttcttaatga acgaggattt cgcgaagata aacggacata cgattaagca
    15301 aaacttcaag acggggcctg tttgggacac ggataagttc tctaccaatc tggtggccca
    15361 tccctatcac ggatcgttat atttcaacgc ggcccgtagc aacggactga atttctggca
    15421 atccattcca ttcgcggcgg gaggcagcct aatgtgggaa ttctttatgg aaacggaacc
    15481 gccctccatc aatgacatgc ttgccacctc tttcggcggt atagaattag gtgagattac
    15541 ctaccggctc tccgacttat tcatcgacaa ccgctcccac ggggcggaac gtgtgggacg
    15601 ggagatctta tccggtttga tatctccgat gcgggcgatc aatcgtatca tcacgggaga
    15661 agcttggaga cacagcagct ccaaggggcg tgtctacacc tcggttcccg taaacttcat
    15721 cgtgggtgtt ggtcctcgct tccttgccga gcaggaaggc tccaagcatg gcactacgag
    15781 catgcacgta tccttcaggt tggattatgg agatcctttc aatgatgatt tctattcgcc
    15841 ctatgaatgg tttcagctga aggccgggtt cgatttcttt tccagccagc cgctcatcag
    15901 ccaagtcaat gccgttgggg ctatctgggg gaaacaggtc tggagtaaag gccctcgtag
    15961 tctggccgct ggaatctttc agcatttcga ctactatgat tccgagttaa aatccaatag
    16021 ttcccaaacg gtagctccct accgcatatc ggaagcggcg gcagtcggtg gtggattgat
    16081 ctattacaaa agaggcacgc cggacaataa ggtagatgtt tacgccgaat tatacggaac
    16141 aggagtcgcc ttgggcgcaa gcatctccga ttatctccgg ctggaagaga gagattataa
    16201 tctgggaagc ggttatagcg tgaaagcgtt taccggattg gcttacgata aacgctgggc
    16261 gttcttgatc gatttggaaa actaccatat cttcacatgg aaaggatacg agccggatat
    16321 agactggaat gcggtggacc ctacaaagtt aaacgtacaa ggcgatgccg gcaacgcacg
    16381 tttaacggta ttttccacca ccttagccta tatgtccaag cataaatgga atattgcgtt
    16441 gcgaaatcgt tatttctccc gccgtaccca ttataagtat cataaagata tagatagctc
    16501 cacgtatgat attatgctga cgcttgggtg gaggatttaa ttcttccgct caagctcacg
    16561 cagattctcc atcttcttgc gctgcataaa ctcatagatg ccttccaaat actccgtcac
    16621 tttttggttt ccgaactcat agaccttaga gaccagccca tccaagaaat cacggtcgtg
    16681 ggatacgacg atcaacgtcc cgtcaaagtc aagcaacgcc tgcttcaaga tatccttcgt
    16741 cttcatatcc agatggtttg tcggctcatc cagaatcagc aagttcacag gctccaacaa
    16801 tagcttaatc atggccagac gtgtgcgctc gccaccggaa agcaccttca ccttcttcgc
    16861 cgagttctcg ccgccaaaca tgaacgcacc cagcagatcc ttgatcttat tacggatatc
    16921 gccttgcgcc acatcgtcta tcgtctggaa aaccgtaaga ttctcatcca gcagggaggc
    16981 ttggttctgg gcgaaataac cgatcatcac gttatgcccc agcgtcaacg tcccctcatg
    17041 ctcgatctct ttcatgatac acttcaccaa ggtagactta ccctcgccat tcttcccgac
    17101 gaaagcgatc ttatcccctc gctcgatcat cagattagcg tttcggaaaa ccgtatgatc
    17161 gccatacgct ttcgagacat tctcgatcgt caccggataa gagcccgaac gaggcgaagg
    17221 cggaaacttc aagcgcaaag ccgaggtatc ttcctcatcc acctccaaga tctccagttt
    17281 ctccagcatc ttcacacggc tctgcacctg caaggtcttg gagtacgtgc ccttgaaacg
    17341 ctcgatgaac tctctcgtct cggcgatcat cttctgttgc tcgtcataag ccttctgttg
    17401 ttgctcacga cgttccttcc gtaattgcaa gtattggcta tagtttacct tataatcata
    17461 aatccggccc atcgtcacct cgatcgtacg agtcgtgata tgatccacga acgcacggtc
    17521 gtggctgatc accactacgg cctgaccgtt atcgatcaag aaatcctcca accactggat
    17581 agactcgata tccaagtgat tcgtcggctc gtccagcaaa aggacatccg gtttcttcaa
    17641 cagtagtttc gccagctcga tacgcatacg ccagccaccg ctgaattcac tggtttgccg
    17701 gtcgaaatcc tcccgtttga aacccagtcc caacaaggtt ttctctatat cggcgtcgta
    17761 attgatctcc tctatggaat agaatttctc gctcaaggta gagacccgct cgatcagctc
    17821 catataacta tccgactcat agtccgtacg agtctccagt tgcttattca attcggcgat
    17881 ctccgcctcc atctcgtgca gatgggcgaa agcctgcgcc gtctcctcga aaacggtacg
    17941 gccatcctcc gtcatcaaat gctgcggcaa ataagcgatc acggtatctt taggggcgga
    18001 cacttttcca cggcttggct cccgcacgcc ggccaatatc ttcaacaagg tagatttacc
    18061 ggcaccgttc ttacccatca aggcgatacg atctttctcg ttaatcacaa aagaaacatc
    18121 cgagaaaagg gcgcttccac caaactctac tgttagtccg tcaactgaaa tcatatgttt
    18181 attttaatac attaatataa tgaagccgcg aagataagaa aaatcccttt cattagggat
    18241 gtacaggaga tttcatacga tctttccggg gcaagactag gaagaaattg gttgccgatg
    18301 ccgtcggcaa tattttcgac gccgtcagca atatttccga cagcgtcagc attattgccg
    18361 acggtgtcgg caaccaattg cataagggac taatccctta aactaccttt aaaaaaagca
    18421 gaagcatcca catattttcc aacaaaacgc ttgttttata aacagaaact cctatctttg
    18481 cacccgctaa tacaaacagc ttaaattaat tattcaaaca tggcaacaaa aattagattg
    18541 caaagacacg gtcgtaaagg ttacgccttc taccaaatcg tgatcgcaga cagcagggct
    18601 ccacgtgatg gaagatttat tgaaaggata ggttcttata atccgaacac taatcctgct
    18661 acagtagatt tgaacttcga aagagctttg tattggttac aagtaggtgc tcaacctaca
    18721 gacacaactc gtaacattct ttctcgcgaa ggcgtttgct tgaaaaagca tttattggaa
    18781 ggtgttaaga agggtgcgtt cgacgaagcc gcagctgagg agaaattcca agcttggttg
    18841 aagaacaaac aagcttccgt acaagctatc aaagaaaaag acagcgaagc agctagagca
    18901 gaagctaaag cacgtcttga ggctgaaaag gaagcgaata aggcaaaagc agaaatcgta
    18961 gctaaaaaga aagcagaatt ggcagcagct gaagctgcta agcaagctga ggaagcagcc
    19021 gcagcggctc ccgctgaaga agctccggca actgaaagcg ctgaataatt cgtgcgatgc
    19081 caaaataaaa aagaggacat ttttcaatgc cctctttttt tatgcctttt ccaccagcta
    19141 ccggatcttc ctaatgcgta taatcgatca gccggatgcc atcgcctaaa tcgttctgga
    19201 taacatcctt catccttttg gcgaaaggac aggcataacc tatcggcgtc cctttttgga
    19261 tacaggaagc aaaagcgata ctatccgccc ctctattcac caactccctc gcccttaata
    19321 cggccttttt tccgggacaa cctccgcaat tgataaaccc gatgatctca atatcttcct
    19381 ctacgccctc aaaggctccc tttttctcac ggatcatcct aaaatcagta gtaccggggc
    19441 aaaaatcctc tgtttgcata catctgataa ttcctacttt cataaagcat ccctcccaat
    19501 taaaaaagcc gtaaaatcta aaattctacg gctttccgat ctataaatga tgattaacta
    19561 agtcgtgtta cttcttcttc aacaagaaag tatcgatctg tttcacaaac tcctcacggg
    19621 gaagagctcc catcgatatc tgaggctgtc cttccttagg gataaacaag aacgtaggaa
    19681 tactttgtat accgaaagcg gcagccaact ccttttcctt atccacattt accttataaa
    19741 ctacgatatc attcttatac aggatagcca aatcccttaa aataggagcc acttgcttgc
    19801 agggaccaca ccagtccgca taaaaatcga tgatacaagg cttatcacct tcatataccc
    19861 atttcgttgc gttcttctcg taattgaata ccttttgcaa gaactctgcc ttgttcaaag
    19921 taacgacctc tcccttggag gcggtaccag cctcacttga tttatctgat ttagcggaca
    19981 tcgagcagct tactaatagc agcacaaccg aaaccagcca taaacttttc aactttctca
    20041 tatagaaacc ttttacttga ttgataaatt atttgctaca aaaatagcaa taaaaagggg
    20101 attcccacac attctattct taaaagaaaa gaataaacaa aaagaaaaaa agcgcataag
    20161 actcttgtat attccaaaag aatgactacc tttgcaaagc aattaaacga aacgtttgat
    20221 cgcaaaacat attggaaaga tggcagagtg gtcgattgcg gcggtcttga aaaccgttga
    20281 accgagaggt tcccggggtt cgaatccctg tctttccgca gaacctactg aacaaaacaa
    20341 gagagtaagt ggacaaaaac ctacaaatcg ctgatttgta ggttttttat tgcctataag
    20401 tcttgtgtcc aatgccttat cagaagaaaa ttcggctcac ctgataatca gtgggggtat
    20461 cttcaggctc atctatattt cagccggcaa cctaagacaa gtcgacctac agaaatatag
    20521 aagtaggcca acagatgaga tcatgggata accattgcca tataaatcgc tgtcttatat
    20581 cctgttaatc aacaggccaa ctcacttgag aaaggcttcc caagtgaata actaaccact
    20641 tccagactcg taagcttacg gctaccccca gccgtaagtt attcacttga caagccgtaa
    20701 gttattcacc tgacaaggca taaattatac attaaccgtc tcttccccga tggttatcgg
    20761 gaaatggcag aggaactata gatacaagtg ccccatttgt ctttttgaca acttgtaatc
    20821 tgaagtcccg gagaaacgat tattccgtac ccaagtgcgt ctcgcttcca aattcgagag
    20881 aaaaaaacag caattctctg tttgatagct gtttgctgaa aaacggcctt tcgttccagc
    20941 cgaaataatt caccctagtt catgttttac ggtcgtaagg cggtaataat gcccaacgct
    21001 accgcatgtg agggccgata cctatatatg tgtaggctta cgccactata tgtgttgctt
    21061 gacgcgacta tatgtgtggg ttaacactgc tatatgtgtg agctgataca gccatatgtg
    21121 taggttgata cgtatatatt cgttaaaaag cgacgcttat cgtgttaaaa agcggtggtg
    21181 gcagcttgtt cgcgctcccc gtttacgccc gttggctttt atagccagag agccgtgtcg
    21241 tgaaaaagaa ggcatttcaa tcaaaaagat accattcatc gcattaagct gacatccgcg
    21301 attcttgtct tatccctttg aattaagtct gtccccaata aatatcgggt gagccaagta
    21361 atcgcatcca gacattgcat ctctatgtaa attcgcaagc gaaactcttg cataatcaaa
    21421 aaaaatcaat acctttgcac ccggtttcaa caagaccttg gagagatgct cgagtggttg
    21481 aagaggcacg cctggaaagc gtgtaaaccc ctaaagggtt tcgcgggttc gaatcccgct
    21541 ctctccgcag aactaaccag ataatgaaca gtcaagtccc acaaatccaa cgatttgtgg
    21601 gactttttag attttttgtt acctacacta aatcttcttg tttgatcgaa taacacttag
    21661 tgtttgtaag atgacagaca atattattac ccctagccct atataaaaag cggcgttcaa
    21721 ctctttagcc tcactaaaaa gaagcatagc caagataatg ctatagatag gttccagatt
    21781 ataactcaag tttaccgtga acgcagagat ctttttcagg acttgtatct gaagtaaata
    21841 caaaccaatc gtacaaacag aagctaaaag caataaataa gtaaaatcta atagcccggg
    21901 aacaatcgtc gatacaggaa tatatcgcaa atagaacggt aaaatacagg aaagcccgat
    21961 aaagccacct accatttcat acaagagcat ggtacttgtt gaataattat ttccgatctt
    22021 cttattcgtg atcgtgaaca aagccgctaa agcggatgat ataataccca aacctattcc
    22081 taaacgatag cgagtatcga aatggaaaat cagtaccacc ccgaataaag tcaacaaact
    22141 aaaaacaacc tccttgaaag acactctatg acaattaatc aatggctcta gaaaagccgt
    22201 aaagaaacct accagagaaa aacaaaccac tccaatagac acattcgaag cctttatact
    22261 tccataaaag aaaacccaat gcaatcccag caataaccct actcccccta ttctcaaggc
    22321 atccccgaaa gaaattcgat tcaatctttt gctgacggat aaaacgagta aaaacaacaa
    22381 agacgcaagc atcatacgat accagaccaa tagggcttca ttcaagctaa tcaattttcc
    22441 aaatatgccc gtcgcacctg ccaaaataat agatatatgc agttttataa atgcgtcttt
    22501 cactatgtca ctattctatt taattatgga caaatgtaca aaggaaatat aagctatcga
    22561 attcaaactt gataaatact ccgtttttta ccctaatggt aacttttttc taaatagaga
    22621 agcctacttt tgtgccgcaa aaataaaaag aaaagaaact gatgatgcaa gacagtattg
    22681 attttggaac aatgaacatt ccgaagttgt tccgtatgat gtttatccct accttattag
    22741 gtatggtcct ttccgccact attaatatcg ccgatggaat attcgtagga agaggcgtag
    22801 gaaatgacgc cttggctgcg gtaaatatcg tggctccttt tttcatgtta gcaaccggaa
    22861 tcgggcttat gttcggagta ggcgcatcta tcgtcgcctc gatccacctt tcacaccaga
    22921 aagtcaaggt agcgaatatt aatatcacgc aagcgctttc ggtctcatta tgtattatgt
    22981 tatcgctttc cttgttagtg atgacattcc gtgctgaggt cgctctttta ttgggtagtt
    23041 ccgagcaatt attgccctcc gtattggaat atatgaactg gatcgtcccg ttccttgcct
    23101 tttacatgtt attgaatatc gggttattca ttatccggtt agacggatca cctacatacg
    23161 ccatgttatg cagcgctatc ccggccctga taaacctaac attagactat attttcgttt
    23221 tcccattgca ttggggatta atgggagccg ctttagcttc cgctatttcc gtaatcgtag
    23281 gaagtattat gatcgtggtt tatatcgtag gtttttctaa agtattacat ctttaccgcc
    23341 ctaaattctc gattaaaagt atcttattga caatccgcaa tatcggatac atggtaaagc
    23401 ttggttcttc cgcattctta actgaggcag ctatcgcttg tatgatgctg gtgggtaatt
    23461 atatattcat gagatacctt ggggaagacg gggttgccgc ctatagtgta gcctgttatt
    23521 gctttcctat cgtattcatg gtgaacaatg cgatcgccca gtctacccag ccgatcataa
    23581 gctacaacta tggcatacag cagtggaaaa gagtacggca ggcgtttaag ttagccctgc
    23641 tatgcgctgt cgtgtgcgga ggactcgcct gcgtgggtac tattttattc tgcccggaag
    23701 tctcctcctt atttctcggt aatcatggca acgcttacga gatagcggtc tccggcattc
    23761 cctatttttc tttgggatat gtctttttcg ctctcaatat cgtttgtatc ggttactacc
    23821 agagcataga acgtttcaaa cccgctacgc tattcactat tctacgagga atcgtgatta
    23881 tcaccctaag tttcatgtac ctacctgttg tctgcggaat taaaggtatt tggctggctg
    23941 tacctttgtc ggaattaatt acttttgtaa tcattgtggt atactatcta ttgaaacgta
    24001 caagagcatg aaagaggaag ttcgccagaa agtgatggaa cggttttcaa tctctgagca
    24061 ggccatgcag ttattgctgg aaagcgcaga gatgatgtcg tttgtcccca aagatataat
    24121 cgtacatgaa ggtgagataa acacgaacat gtatatctta tccaagggaa tctggcgggc
    24181 ttatacattt aaagatggga cggaagatac cttttggttc gccgtggaga gcgagatcgc
    24241 actcccggta tggggatata cttccggctc tccttctctt tataccatag aagccgttac
    24301 ggaaagcgag gcgtattgcc tatccaaaca gaaactagaa atcctatttc aatcctccgt
    24361 gcaattagca aatatcggaa gaaggattct agagaatttt atgcttgaga tcgagacttc
    24421 atggttaagt tcttacaaac gaaccgccat tgaacgttac gccattctat tggacaagca
    24481 gcccgaaatc atccaatccg tccccctaaa atatatagct tcttatctag gtgtcacggc
    24541 tcaatcctta agtagaatcc gggcgaaatt agctagttct ttaaccttta tcgtgtaaag
    24601 cctcttcatt tttataacgc atcgataacc aacctctgac ttttcataaa gtcaatacgt
    24661 taaatccgta aataacgatc aataatctca taataacttt ctatcgcatt agcggatcgg
    24721 agcaagttca tatcgaaagt cactctatta tacaagtgat ttcctatgat ctgatcccaa
    24781 cttacaggaa atttgcgcaa cctcatcaat cgtaaaagcg acctctcccc gaagcctgcg
    24841 gtacaccgcc tctctcccga tacataaagt atccgtcaag aaattagcaa gattttgtcc
    24901 gggaggaaac ctatctttca ttgcggttat caattcattt acaatactat ctttcattgc
    24961 cttatacctt atttccaact attaatattc cttgatacat ttggcaaatg taaaacatgt
    25021 aaacgatagt tttgtacgat aaagcaagcc tatgagaatt gttccttttc taattaaagc
    25081 aaacacagac agaaaaagat agaaaacgaa attaaactaa aaaagcacct ataaatttcg
    25141 aatcgcgcaa tcggaatatc taggttgttt catttatcga aacaggttca aaccctaaag
    25201 cgtatttata atctcccttt gtctattgaa aaactggata cgttgcatct ctccactctc
    25261 ggagatcatg gtagagaact tttttaaaga ttgaatccag tctttcaagc tattaaacat
    25321 ctcagaatcc tgtgtcgtaa tagaatttat cgagtaaacc cgtatcatac ttaactgcaa
    25381 agaacttgtt tccagataac tatacgtagc ctcaaagtta atatgcgata cataaattcg
    25441 tacactattg ccagcctcgg tctttcctct catggcaagt tcttccaatt catccaccaa
    25501 cactaataac tcctctttga tacgttgtat atcctcacag gaaataagat ggatatcgga
    25561 gaaatattta atgtcattga ccaaatgatg gaagatcata ttatcccaaa tataatccgt
    25621 agaatggata tactgtgtca acgatacaaa ttctctttgg gtatcaacca gtttttccgg
    25681 tatcttcaga ttctcaaaat gattgcattg gatatgctta ttctgataca tccacttaaa
    25741 taaacgaaac tttgacaaaa ggtcatgctt caaataaagg atctgaggaa tagtattgga
    25801 agaggtaccc aaagccgtag taggatcatc ctgaaaggcc ctaaagatct tcacatatct
    25861 agacaagatc gtaaaataag cattaaaagg atcatcgtga tctaccacat tcaagtcgaa
    25921 cacggcattg gcactaaaac taacccctac tattttatcc aatgacacac ccaatttcct
    25981 tgagataaga gctgcctctt ccaaggtgaa aggaacctcg ccacgtaagc gcctataaat
    26041 ggcttctctg ccaatataaa gggtatccat caacagattc gccaaatttg tcttaggggg
    26101 aagtttttct tttaaagctt caatcaagcc tgtatttaat tcatttatca tcataaccat
    26161 gtcgaatgaa aaatcatcta ctctagtaac atatatagag aggaagttgt ttcgaggaca
    26221 agtacattcg tagatggatt ttcaaagcac gtagcttttc agcttattca tatcaactat
    26281 tttcccttcc cgggaaatag ccccttcctc tatcatttcc gagaaactac gggccaatga
    26341 aggacgggcc actccaaaat attccgaaag ctctgtttga ttacgatcct gcttataatg
    26401 atctccttga atacgtttaa gtatatagta agccagttta cctttaatgg tcttaatcga
    26461 taataattga agacgttcag aaagaaattg tgtccggttg gcgttaaaag ccatatagct
    26521 ttgaagaaaa tgctcgtttg tcgccagcaa acgcatcacc gcattcttag gtattaaaat
    26581 gatctcgcat tcctccaagg cgataacatc taccgggaag cgattatttt ccgcaaacaa
    26641 aaatgcggag gccaaaggag taggcgccga taaagtctcc acttccagaa ttgtcccgct
    26701 ttcggtgatc atctcagtct ttacccgtcc tttactcaat agataaagcg aagataaggc
    26761 atctccctga cgagccaccc agtcaccttt cttaaacgac cttgtcgaat aatccaacga
    26821 actgaaaaga gcggtttgct cttcctcaga caattttccg caaataggac acaaactcag
    26881 attcataaaa cttccttttg cggataaaga taaagaaaat aatcaaagag tgtaacaact
    26941 gttacaggtt aaacgatcgt ctatccccta cattcgcgat aaacttataa aataaaagct
    27001 atgttctgtt atcaatgtca agaaaccgcc caaggaaagg gctgtatatt aaaaggtgta
    27061 tgtggtaaga ccgccgaagt ggccggatta caagatttac tgatgtactt aatgaaggga
    27121 atctccaaac taacaacgac tttacgcaag cgaggcgtgg aatcagccac ggccaataag
    27181 ttcatcgtcg acggactttt catgaccatc acaaacgcca atttcgattc atccagattc
    27241 gtctcaaaga tcaaagaagc ctatcagcta cgggagaacc ttctcgacga gctacatcga
    27301 cagggaatcc atccatcctt aacctgcgat tgtctgactt ggaaatcgga caaagtagag
    27361 gaaatggagg tcaaatcgaa agaagtaggt attctcgcca cagaaaacaa ggatatccgc
    27421 tctctacgag aattactcac ttatgggata aaaggtatgg ctgcctacgt ggaacacgct
    27481 tacaatctag gcttcgagga taccagcctc tatgccttta tccaagacgc cttggtcgca
    27541 acgactcaat cggacctgac cgtcgccgat ttaacccgat gggtactcac ctgcggcgaa
    27601 tacggagtaa aagccatggc cttattagat aaagcgaata cttccaccta tggcaacccg
    27661 gaaattacga aagtgaatat cggcgtagga aagaacccgg gtatacttat cagtgggcac
    27721 gacttgagag acattcaaga cttgctggaa caaaccgaag gtacaggcat agatgtctat
    27781 acacatagcg agatgcttcc tgcacattat tacccggctt tcaagaagta taagcatttt
    27841 gtaggaaact acggtagcgc ctggtggaaa caaacatctg atttcgagac attcaacgga
    27901 gttatcctgt ttacgaccaa ctgccttgtc cctccccgtt cttccgccac ttatgccgat
    27961 cgggtctata cgaccggctc taccgggttc gaaggattcc cacatatcgc cgatcgtaag
    28021 cccggaggct ctaaggattt ctctgcgtta atcgaacacg caaagaaatg cgcccctcca
    28081 acggaaatcg aacatgggga aatcatcggt ggattcgctc atgagcaggt attccaatta
    28141 gccgacaagg ttatcgatgc cgtaaaatca ggagcgatac gtaaattctt tgtcatggca
    28201 ggttgcgacg gaagaatgaa gagccgtagc tactataccg aattcgccga gaaattaccg
    28261 aaagataccg tcatattaac cgccggttgt gccaaatatc gttacaacaa actgcctttg
    28321 ggggagatca gaggtattcc acgggtatta gatgccggac aatgtaatga cagttactca
    28381 ttggtgatga tcgccctcaa gttaaaagag atcttcgggc tggatgatgt caatgaatta
    28441 cctatcgcat acaatatcgc atggtacgag caaaaagcgg taatcgtatt actcgcccta
    28501 ctctacctag gcgtaaaaaa cattcactta ggaccgacat tgccagcgtt cttgtcgccg
    28561 aatgtagcca aagtattggt cgataatttc gggatcgccg gaataggtag cgtggacgaa
    28621 gacatggaac tatttctagg aaagtaaaat aaacctttcc cgatccgctc ttgttttcct
    28681 atcacatttt aatcgattca agatgaataa ggaacaacaa aaaagagtag ccgccattca
    28741 tgacctatcg ggatttggca aatgttcatt gacagttgcc ctcccgatcc tctcggcggc
    28801 aggaatagag acaagcgcct tacctacggc catactttct acacacacag gaggtattct
    28861 cggctatact tatagagact tgacggaaga tatgcgtccg ttcatgaagc attggaaaga
    28921 attggatatc cgtttcgacg ccgtctacag cggctttctt ggatctttcg agcaattaga
    28981 tatcgtaaaa gagttcttct cccttttcaa gcgggaagat aacctgattc tagtcgatcc
    29041 tgtcatgggc gataacggag aactatacaa gatattcacc cctaaattcg ccaaaggaat
    29101 gagatccctt tgtgaaaaag cggacattat cgtaccgaac ctgacggagg ccgcattatt
    29161 gttgggcgaa ccctaccaag caggtcccta taccaaagct tatatcgatg gtattttaca
    29221 taaactaagt cagctaggcc ctaagcaagt tgtcttgacc ggtgtctatt tcgacgagaa
    29281 agaactggga gccgccactt tcgatatgga acgaaatgcg acaga
//
LOCUS       DBMDTB010000043        28728 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_598_length_28728_cov_11.479198, whole genome shotgun sequence.
ACCESSION   DBMDTB010000043 DBMDTB010000000
VERSION     DBMDTB010000043.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 28728)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 28728)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28728
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_598_length_28728_cov_11.479198"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..609
                     /locus_tag="ACZPB4_08590"
     CDS             <1..609
                     /locus_tag="ACZPB4_08590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010183873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HIR1098309.1"
                     /translation="ICAKHNILVISDEIHAEMAYPQYTHYPFASVSDTAASCSMTFMA
                     PSKTFNIAGIVTSYAIVPNDRIREEFYSFLEAGEFGDGTIFAYTATTAAYTYGAEWLQ
                     QMRMYIMENVRFVEEFMKQHLPKIKVYQPQASFLVWLDCRELKLSQEELVHLFKDKAG
                     LALNDGSIFGPGGEGHMRLNIGCPRSVLDKAMNALKKAVDKK"
     gene            658..1233
                     /locus_tag="ACZPB4_08595"
     CDS             658..1233
                     /locus_tag="ACZPB4_08595"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HIR1098310.1"
                     /translation="MKITANKYVAVTYDLNVGEGEERELMEKATVEAPLKFIYGTGMM
                     LPAFEKALNGLEVGGTFNFSIEPAEAYGEYNEEHVLDLPKNIFEVDGKFDAEMIKEGN
                     TVPMMDSNGNRMNGSVLEVKDDIVVMDFNHPLAGETLHFSGEVIDVHEPTAEEIAAFS
                     APAGGCSCGCDDCGSDCGDNHEGGCGCGGCH"
     gene            1337..2413
                     /gene="aroC"
                     /locus_tag="ACZPB4_08600"
     CDS             1337..2413
                     /gene="aroC"
                     /locus_tag="ACZPB4_08600"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HIR1098311.1"
                     /translation="MNTFGNIYRLTSFGESHGPGIGGVIDGCPAGIELDTAFIQQELN
                     RRKPGQSRITTPRKEDDEVQFLSGIYEGKTTGTPIGFIIWNKNQHSSDYDNMKTVYRP
                     SHADYTYQTKYGIRDPRGGGRSSARETIARCVAGAIAKLALKQYGIQIQAYTSQVGPI
                     QLAGSYQDYDLSLTEESDVRCPDPKTASEMETLIAEVKSKGDTIGGIITCVAKGVPVG
                     LGEPVFGKLHAALGHAMLTINAVKGFEYGDGFNAAFFRGSERNDRFFNDNGHINTRTN
                     NSGGIQGGISNGQDIYFRVAFKSVATILMEQETVNMEGEDTILKARGRHDPCVLPRAV
                     PIVESMTAMTLLDYLLIQKTRENF"
     gene            2426..2746
                     /locus_tag="ACZPB4_08605"
     CDS             2426..2746
                     /locus_tag="ACZPB4_08605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HIR1098312.1"
                     /translation="MAWILLIIAGLFEIGWPLGFKLASMHSKYFIWFIGLSILSMGLS
                     GYFLYLAQKSIPIGTAYVIWTGIGAIGTVLLGILFFHDSANIFRLLFLSLILIGIVGL
                     KLVH"
     gene            complement(2853..3326)
                     /gene="rlmH"
                     /locus_tag="ACZPB4_08610"
     CDS             complement(2853..3326)
                     /gene="rlmH"
                     /locus_tag="ACZPB4_08610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HIR1098313.1"
                     /translation="MKIGLIVIGKTDAGYFVEAINEYKNRLTHYIPFEMEVIPDIKNV
                     KNLSEAQQKEKEGELILKALQPGDYLVLLDEKGKEFTSMQFSTYLEKKMHAVLKRLVF
                     VVGGPYGFSEAVYKAASEKISLSKMTFSHQMIRLIFIEQIYRAMTILNNEPYHHE"
     gene            3415..3786
                     /locus_tag="ACZPB4_08615"
     CDS             3415..3786
                     /locus_tag="ACZPB4_08615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4783 domain-containing protein"
                     /protein_id="HIR1098314.1"
                     /translation="MKRLLLTFALIFAFVCAQAADITSISNAFKAGNASSLSGAMDKV
                     VDVALPGSSKKCNGSEAVSMLSSFFSSNKPSGFSVVHHADKKESGFLVGKLPTSSGEY
                     RVNITYRAEGNTAIIQSIRIE"
     gene            3790..4629
                     /gene="nadC"
                     /locus_tag="ACZPB4_08620"
     CDS             3790..4629
                     /gene="nadC"
                     /locus_tag="ACZPB4_08620"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005809499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004514 - nicotinate-nucleotide
                     diphosphorylase (carboxylating) activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD+ biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HIR1098315.1"
                     /translation="MDKLIDDLIKLAFAEDIGDGDHTTLCCIPETAMGKSQLIIKEDG
                     VLAGVEMAKRIFHDFDPELKMTVFIQDGAEVKKGDIAFVVEGKIQSLLQTERLMLNVM
                     QRMSGIATTTRKYAKALEGTKTHVLDTRKTTPGMRMIEKEAVRIGGGMNHRIGLFDMI
                     LLKDNHVDFAGGIEQAITRAQNYLKEKGKSLKIEIEVRNFDELEQAMKVGGIDRIMLD
                     NFNIENTKEAVRRINGRFEVESSGGITFDTLRDYAECGVDFISVGALTHSVKSLDMSF
                     KAC"
     gene            4820..6256
                     /gene="aldA"
                     /locus_tag="ACZPB4_08625"
     CDS             4820..6256
                     /gene="aldA"
                     /locus_tag="ACZPB4_08625"
                     /EC_number="1.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="HIR1098316.1"
                     /translation="MKELKMFIDGRFIENESGKWIKVLNPSTEEVISLMPDGTVEDAR
                     KAIDAAEKAQNQWERTPSIERAAYLTKIAAGIRKREKELTDIIVREGGKTQGLANVEV
                     LFTADYMDYMAGWARRYEGEIIPSDRPHENIFLFKRPIGVTTGILPWNFPFFLVARKA
                     APALITGNTIVIKPSQLTPENAYVFAQIVEEAGLPAGVFNLVNGRGSVIGHELSANPK
                     VGMVSLTGSVGAGQQTMAAAAPNITKVSLELGGKAPAIVMKDADVDLAVKSIIASRVI
                     NTGQVCNCAERVYVDKAIKETFMEKLVAGMKQVKVGNPNEIADLDMGPLIEASALKSM
                     EKKVERAIQQGARLLCGGHRIGTKGYFFEPTVLDCVTQKMDIIQEETFGPVLPVVEYS
                     DINDAIAWANDCEYGLTSSVYTQNLNNAFKVMRSLKFGETYINRENFEAMQGFHAGWR
                     KSGIGGADGKHGLEEYLQTQVVYLETKE"
     gene            complement(6302..8062)
                     /locus_tag="ACZPB4_08630"
     CDS             complement(6302..8062)
                     /locus_tag="ACZPB4_08630"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HIR1098317.1"
                     /translation="MDNYIVSARKYRPSTFRSVVGQKSLTTTLKNAIQSNKLAHAYLF
                     CGPRGVGKTSCARIFAKTINCLNPTADGEACNACESCRAFNEQRSYNIHELDAASNNS
                     VDDIRTLIDQVRIPPPIGKYKVFIIDEVHMLTTAAFNAFLKTLEEPPHHALFILATTE
                     KHKVLPTILSRCQIYDFSRISIADMVEHLQYVSSQEGVTAEPEALNVIAQKADGGMRD
                     ALSIFDQVVSFTNGNITYQAVIDNLNVLDYEYYFRLTDAILSGNVRASLLILNEILGK
                     GFDGQNIITGLAGHFRDLLVCRDESTLVLFEVGASIRERYKEMAKHCPDQLLFKAIEL
                     ANACDLNYRASRNKRLLLELTLIQICQLTQVAVDDKKKALIEPIAGTNPSSQAVNSGQ
                     PQQPPQAPSVTAAAGAPQVMSTHMPSSVPAPPPSTAPNPARRTARPMGISMKEIGVEK
                     PKQQTVQQATTNVKEVVTPFDNDSLVREWDNYAATIDKKVYLKNTMINCKPTLQENYY
                     FEVAVHNPGQQEELINNAIHILPFLRQHLNNSRIQMRVRIVEGNEKHLAYTSTEKLEL
                     LMKINPTLGRLRDEFNLTLD"
     gene            8132..8437
                     /locus_tag="ACZPB4_08635"
     CDS             8132..8437
                     /locus_tag="ACZPB4_08635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsB family cell division protein"
                     /protein_id="HIR1098318.1"
                     /translation="MSRIKEFYIKYLSWINAYWLVTIVFLIVTFTVGDSSLYKRYTYD
                     EKIRGLEKEIKHYQKEIEINSKKLNDLHTDKEGLERFAREEYFMKRSNEDVFIIKDK"
     gene            8438..8761
                     /locus_tag="ACZPB4_08640"
     CDS             8438..8761
                     /locus_tag="ACZPB4_08640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098319.1"
                     /translation="MNQQIRSIIFGVAGLLVLAGAVLFLTHWAIAPYLFAVGAAGIAV
                     CYLTLPVKDLDFRRRRLHRFNVFAGLLMIVSSGFMFNNRTEWILCLSVAAILQVYTAF
                     VTPKE"
     gene            complement(8936..9541)
                     /locus_tag="ACZPB4_08645"
     CDS             complement(8936..9541)
                     /locus_tag="ACZPB4_08645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OmpH/Skp family outer membrane protein"
                     /protein_id="HIR1098320.1"
                     /translation="MKNINYVINGVLAVAVVILYIMQFSGKKESSVTRTFASAGDTTA
                     LLPIAYVNVDSLLLNYNYSKDLNEIILKKQENSRANITQKARSLQGEMQDFQRKVENN
                     AFLTRERAEQEQQRLLNKQQELQNLDNQLAQELMQEQQKLNEQLRDTVVSQLKAFNLG
                     RGYQVVFSNTVGDNILLAGDSYDITGELLEYLNKNYSSPAK"
     gene            complement(9567..9785)
                     /locus_tag="ACZPB4_08650"
     CDS             complement(9567..9785)
                     /locus_tag="ACZPB4_08650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098321.1"
                     /translation="MLTTLLFTVIILVISVVLLSIKVLLKKGGRFPNTHIEGNRALGK
                     KGIFCAKTMDRMAVKQKGLYDIMNEIKE"
     gene            9933..11390
                     /locus_tag="ACZPB4_08655"
     CDS             9933..11390
                     /locus_tag="ACZPB4_08655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008154611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-histidine dipeptidase"
                     /protein_id="HIR1098322.1"
                     /translation="MKITDLKPTIVWKFFHQVTQVPRPSKKEGKMIEFLESFAKEYKI
                     AIKKDEAGNLLMSKPATPGMEDRPVVVLQSHMDMVCEKNNGTKHDFDNDPIETIVDGE
                     WLRANGTTLGADNGIGVAAELALLASDDIQHGPIECLFTVDEETGLTGAKALKEGFMT
                     GDILLNLDSEDEGEIFMGCAGGKDTQATFHYEPVPTSDKMQYFRIDVKGLNGGHSGGE
                     IHKGLGNANKILVRFLFLLKKKYDFVLCSIDGGNLRNAIAREAHAVIGLHPENKEDVR
                     ILLNHFAADVENELKHVDPNVQLAMESTDRPEYHIDNATAEKLIYALHACPHGVIGMS
                     HDIEGLVETSTNLASVKMKEGDTILVGTSQRSSIESCKIAIANTVASTFLLAGADVKH
                     GDGYPGWAPNPDSKILKIAQETYKRLFNKDAKIMAIHAGLECGLFLEKYPKLDMISFG
                     PTLRDVHSPNERIEIATVGLWWSHLLELLKSIPAK"
     gene            11541..13028
                     /locus_tag="ACZPB4_08660"
     CDS             11541..13028
                     /locus_tag="ACZPB4_08660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098323.1"
                     /translation="MKRLTITLFILATLLLNMLPACDGLDDHYSTNPTYRLSFSTDTL
                     AFDTIFSTIGSTTRQFMIYNKNSEPLSIESIMLASGESTGFRMNVDGRKGSSFNNVGI
                     LANDSMYVFVEVTVDPNGGNQPLLIQDSVLFTVNGIRQSVLLEAYGQDVNLYKGGVTI
                     TKDSILTANRPYLIYDSLVIAKGVSLNIEKGATFYMHDKASLIVHGSMNALGTLDEPI
                     TFRGDRLDYILNDILPYDRTPGQWGGITFKADSYGNVWDNVIVRNGTSGVYCEPSTPD
                     RPKIKINNSQITNMGSDLFFAINCDVIATNTEFSNAGGSVLTLVGGKYYFAHCTMANY
                     MSLTKREMASETVPLDSKCLYLLNNVTVDGNGPYPITQAYFDNCTIDGSYDVELKADG
                     STDFDYRFNHCALKAKESSSDHFKEVLFIKKTPSYRKVGGKQNKYTYDFRPDSVSTTG
                     VGKADPEITKNYPIDRYGVNRLTSSNGPTIGAYEFVQEETEDSNE"
     gene            13068..14114
                     /locus_tag="ACZPB4_08665"
     CDS             13068..14114
                     /locus_tag="ACZPB4_08665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HIR1098324.1"
                     /translation="MKIFMFFLLFFASPPLFAQATFKVMTYNVENFFDTRDNPTKNDD
                     EFLPSGNRYWTQSRYYHKLQQIAKVISAAGEWSTPALIALCEVENDSVLSHLTRRTPL
                     RWQDYRYIITQSPDPRGINVALLYQRNQFFYLRHESIPIRFSGNKHKLTRDILHVYGK
                     IITGDTLDVFVCHFPSRYGGEKESEKDRFDAARTLRGSSDSLLLIREKPQILIMGDFN
                     DTPQDRSISEIFAAQAFPENTQITDSTSCTYYNLFASPHITQFPGSHKYQGEWSQLDQ
                     IIVNRDLITQESSMHIIPESIHIFAPDFLLTKDKTWRGVRPFRTYYGFKYEGGFSDHL
                     PLTVDFLIRSQIKR"
     gene            14202..14846
                     /gene="pdxH"
                     /locus_tag="ACZPB4_08670"
     CDS             14202..14846
                     /gene="pdxH"
                     /locus_tag="ACZPB4_08670"
                     /EC_number="1.4.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004733 - pyridoxamine phosphate oxidase
                     activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase"
                     /protein_id="HIR1098325.1"
                     /translation="MEINLASIRQEYTKGGLRESELPDNPFLLFSQWLQEAIDSKVDE
                     PTAMLVGTVSPEGKPSTRTVLLKDLHDDKFIFYSNYESRKGRQLAQNPAISLSFVWHQ
                     LERQVHIEGTAEKVPPDESDQYFKKRPYKSRIGARISPQSQPIGSRMQLIRAFIREAA
                     RWIGKEVERPAHWGGYAVIPERIEFWQGRPNRLHDRIVYTLQPDGHWKKERLAP"
     gene            14934..16622
                     /locus_tag="ACZPB4_08675"
     CDS             14934..16622
                     /locus_tag="ACZPB4_08675"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M23 family metallopeptidase"
                     /protein_id="HIR1098326.1"
                     /translation="MNIRSIYLAGLFAIIGSHIINTNAQQLRNPFDFPILLSGNFGEL
                     RSNHFHSGIDFKTQGVEGKPVHTVQEGYVSRISVSPWGYGNGLYITHPDGTTTVYGHL
                     QKFSKKIANYVKEQQYAQESFNVNLFLTPDLLPVEQNEVVALSGNTGSSGGPHLHFEV
                     RDTETEEVMDPLDYFSDRITDTRPPKIQGIQIVPIEGKGVVNGKSKKLEIKPVTAKNG
                     KQTITGKIEAWGEIGLAVKAYDYMDNTTNIYGVREITLTADSQVIFHSNLDKFAFDET
                     RYLNTFTDYEEWKDHRSFYMRSFIEPGNRLRFLESVNRGILRIDEPRTYHLTYTLADA
                     FGNATRLSIWIEGKKQEIPQIDTTHTELFHWGGENRFGAKGIRLVMPKGNLYNDLYFR
                     YSVKEDSTSLSATHILHDKPIPLHGTAQLSLFLQSDTLENKQQYGVVRLQNGRASWMG
                     GTYRNGWIDANIKELGSYKIQQDTKAPVITPINQQTWINKQNFIFRLSDNLSGVQTYR
                     GEIDGQFVLFEMNNKSVITYRFDKERLQRGKHELKLIVTDACGNESIYTHPFTW"
     gene            16757..18505
                     /locus_tag="ACZPB4_08680"
     CDS             16757..18505
                     /locus_tag="ACZPB4_08680"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HIR1098327.1"
                     /translation="MENNDLLEMVRSKAQGWLTKSYDAETRAQVQALLDNEDPTELIE
                     CFYKDLEFGTGGLRGIMGVGSNRMNIYTVGAATQGLSNYLKKEFADLEQIKVVIGHDC
                     RNNSRKFAEISADIFSANGIKVYLFEDLRPTPEMSFAIRKLGCQSGIILTASHNPKEY
                     NGYKAYWDDGAQMIAPHDKNTIAEVNKIRNASEIKFKGNKELIEIIGQAIDDEYIKEL
                     TTISLSPEAISRHKDMKIVYTPIHGTGVKLVPAALKAYGFTNIIHVPEQDVVSGDFPT
                     VISPNPEEPAALAMAVEKAKETDAELVMASDPDADRVGAAVKNNEGEWVLLNGNQTAL
                     MFVYYLITRWKELGKINGKEYIVKTIVTTETIKTIAERNGVEMYDVYTGFKWIANVMR
                     ENEGKKNYIGGGEESYGFLCEDFVRDKDAVSACVILAEIAAWAKDQGLSLYQLLQKIY
                     VEYGFSKEKGISVVKKGKSGAEEIEAMMKKFRENPLTEIAGSKVTYFYDYSTLKGKDY
                     AENETVTLDMPTTSNVLQYFTEDNTKVSIRPSGTEPKIKFYCEVHSKVKSIDELPEAE
                     KAAEEKINQIKASLGI"
     gene            complement(18568..19044)
                     /gene="cdd"
                     /locus_tag="ACZPB4_08685"
     CDS             complement(18568..19044)
                     /gene="cdd"
                     /locus_tag="ACZPB4_08685"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0008655 - pyrimidine-containing compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HIR1098328.1"
                     /translation="MKELKLETRVEVYAVGELDNIYRQLYEAAFEASKKAYAPYSKFH
                     VGAAVLLENGEILSGNNQENAAYPSGLCAERTTLFYAGARYPDAAVQILAIAAMKDGE
                     RVDLITPCGACRQVMLETEQRYNKPMKVLLCGKEEAYLVPSATALLPFCFSKSDLI"
     gene            19170..19901
                     /locus_tag="ACZPB4_08690"
     CDS             19170..19901
                     /locus_tag="ACZPB4_08690"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HIR1098329.1"
                     /translation="MHSMLLTSDKDPMGAAIIDYLAHGKASKLRVFSSMFDEDEIPVN
                     QLFRTFQEMPSLEQKALQLSTGKILDVGAGSGCHTLALQEMGKEVTAIDISPLSVEAM
                     NKRGVKDARLQNFFDKSLTGPFDTILLLMNGSGIIGKLENLPAFFHRLKEVLARDGQL
                     LLDSSDLSYLFEDEDGNLDIAPEDDYFGEIDFRMQYKSIKGDSFDWLYIDFNTLNLYA
                     RQAGFKAEKIEDGEHYDYLARISYF"
     gene            19975..20883
                     /locus_tag="ACZPB4_08695"
     CDS             19975..20883
                     /locus_tag="ACZPB4_08695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HIR1098330.1"
                     /translation="MRLSLHFLGILLLSLVCLSAGAESQRKLTSYQKYISKYSDLAIQ
                     HQKKYRIPASITLAQGLLESGAGQSDLARRSNNHFGIKCHSDWRGGRVYHDDDLRGEC
                     FRKYKRVEDSYDDHSRFLAERSRYERLFKLNIKDYKGWAKGLQKCGYATDRAYANKLI
                     KVIEDYELYRFDSGKGTKKTSTKKQNLPVFNYQVYRTHGLIYVYAKDNDSFDQIARSM
                     GFKAKQLMKFNEVPEDFPLQAGDIVYLEKKKKKADKPNYDHVVQVGESMHSIAQMYGI
                     QIKSLYKMNKKDKDYIPEEGDVLKLR"
     gene            20930..22096
                     /locus_tag="ACZPB4_08700"
     CDS             20930..22096
                     /locus_tag="ACZPB4_08700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010992214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIR synthase related protein"
                     /protein_id="HIR1098331.1"
                     /translation="MSDQRYNLRGVSASKEDVHNAIKNIDKGIFPKAFCKIIPDILGG
                     DPEYCNIMHADGAGTKSSLAYMYWKETGDLSVWKGIAQDALIMNIDDLLCVGAVDNIL
                     VSSTIGRNKLLVPGEVISAIINGTDELLAELREMGVGCYATGGETADVGDLVRTIIVD
                     STVTCRMKRSDVIDNKNIQGGDVIVGLASSGQATYEKEYNGGMGSNGLTSARHDVFSK
                     YLAQKYPESYDAAVPEELVYSGGLKLTDKIEELGIDAGKMVLSPTRTYAPVIKVLLDK
                     LHSQIHGMVHCSGGAQTKVMHFVENKRVTKDNLFPIPPLFRTIQEQSGTDWSEMYKVF
                     NMGHRMEIYIAPEHAEEVIGISKSFGIDAQIVGFVEEADKNELIIESEKGRFTY"
     gene            22106..23215
                     /gene="prfA"
                     /locus_tag="ACZPB4_08705"
     CDS             22106..23215
                     /gene="prfA"
                     /locus_tag="ACZPB4_08705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HIR1098332.1"
                     /translation="MAENSLLGKLDGLVSRFEEVGTLITDPAVIADMKRFVKLNKEYR
                     DLEKIVGARSEYVKVLNGIEEAKALLESEQDPEMREMAREELDTCNERIPALEEEIKL
                     LLVPADPQDDKNAIVEIRGGTGGDEAALFAGDLYRMYVKYCELKGWKISVSSFSEGSS
                     GGFKEIIFTVSGEKVYGTLKYESGVHRVQRVPATETQGRVHTSAATVAVLPEADEFDV
                     EINEGEIKWDTFRSGGAGGQNVNKVESGVRLRYVWKNPITGVSEEILIECTETRDQPK
                     NKERALTRLRSFIYDKEHQKYLDDIASKRKTMVSTGDRSAKIRTYNYPQGRITDHRIN
                     YTIYNLSAFMDGEIQDCLDHLIVAENAERLKESEL"
     gene            23247..24089
                     /gene="pyrF"
                     /locus_tag="ACZPB4_08710"
     CDS             23247..24089
                     /gene="pyrF"
                     /locus_tag="ACZPB4_08710"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HIR1098333.1"
                     /translation="MNKQQLFENIKKKQSFLCVGLDTDIKKIPQHLLSEEDPIFAFNK
                     AIIDATADYCVAYKPNLAFYESLGTKGMMAFEKTVAYLRENYPDQFIIADAKRGDIGN
                     TSEMYARSFFDHIKVDAVTVAPYMGEDSVKPFLIYPEAWVILLALTSNKGSHDFQMTE
                     DANGERLFEKVLKKSQEWATDEQMMYVVGATQGKMFLDIRKQAPNHFLLVPGVGAQGG
                     SLAEVAQYGMNDQCGLLVNSSRAIIYADKTEAFANVAREAAHAVQKEMAGYLHDKGII
                     PCKA"
     gene            24179..25222
                     /gene="lpxD"
                     /locus_tag="ACZPB4_08715"
     CDS             24179..25222
                     /gene="lpxD"
                     /locus_tag="ACZPB4_08715"
                     /EC_number="2.3.1.191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016410 - N-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-3-O-(3-hydroxymyristoyl)glucosamine
                     N-acyltransferase"
                     /protein_id="HIR1098334.1"
                     /translation="MEFSAQQIAGFLNGTIEGDPNVKVSNFSKIEEGKPGTLTFLANL
                     KYAHHIYNTEASIVLVNNDFKPEQPIRATLVKVENAYAALAMLLNLVEQSKSKKKGVD
                     STAFIAASATVSDDCYVGNFAYIGEGVKMGKNCMVYPHAYIGDHVTVGDNCVFYPHAT
                     VYENCTIGNNCILHAGSVVGADGFGFAPEGETYKKIPQLGNVIIEDDVEIGANTTIDR
                     AVMDSTIIRRGVKLDNLVQIAHNVEVGENTVMAAQVGIAGSVKVGKHCMFGGQVGLAG
                     HIHVADHVVFGAQAGVISDVKEATTLLGAPAINAKNFMRSSAIFNRLPDIYRSLGQMQ
                     REIEQLKKEINKQ"
     gene            25229..26614
                     /locus_tag="ACZPB4_08720"
     CDS             25229..26614
                     /locus_tag="ACZPB4_08720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008759880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0103117 - UDP-3-O-acyl-N-acetylglucosamine
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-3-O-[3-hydroxymyristoyl]
                     N-acetylglucosamine deacetylase/3-hydroxyacyl-ACP
                     dehydratase"
                     /protein_id="HIR1098335.1"
                     /translation="MQKQKTLAASFSLKGKGLHTGLDIEITFNPAPENHGYKIKRVDM
                     EGQPTIDALAEDVVNTQRGTVLSKNGVQVSTIEHAMAALYAYEIDNCLIEVNAPEFPI
                     LDGSSRFFSEEIQKTGVVEQNAPKDYYIVKHKIEVKDEETGSSLIILPDDKFSVNVLI
                     SFDSPVLSNQFATLNDLSEFPTELAASRTFVFVREVEMLLNHNLIKGGDLDNAIVIYD
                     QKIPQESLDKLADMLNIPHKNVQELGYINNKPLVFDNEPARHKLIDVIGDIALIGKPI
                     RGRVIATRPGHKINNQLARMIRKDIKMNEVQAPVYDPNREPVMDINRIRELLPHRYPF
                     LLVDKIIEVGGNYIVGVKNITTNEPFFQGHFPQEPVMPGVLQVEAMAQTGGLLVLNSV
                     DEPERYSTYFMKIDGVKFRQKVVPGDTLILRLELLAPIRRGISTMKGYVFVGDKLVSE
                     AEFMAQIVKNK"
     gene            26632..27417
                     /gene="lpxA"
                     /locus_tag="ACZPB4_08725"
     CDS             26632..27417
                     /gene="lpxA"
                     /locus_tag="ACZPB4_08725"
                     /EC_number="2.3.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008780 -
                     acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine
                     O-acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP--UDP-N-acetylglucosamine
                     O-acyltransferase"
                     /protein_id="HIR1098336.1"
                     /translation="MNISPLAVVHPEAQIGQNVTIDPFAVIEKDVVIGDNCRIYSHAV
                     ILDGARIGKNCNIFPGAVVAGIPQDMKFAGETTTAEIGDNTTLRECVTINRGTASKGK
                     TVVGRDCLIMAYSHVAHDCVLKDHIIIGNASQIAGEVEIDDFAIVSGGSLVHQFTRIS
                     KHVMVQGGSRIGKDIPPYTLIGRDPIVYCGINIVGLRRRGFTNQQVFLIQDIYRTLYT
                     RGLNNTEALKAIETEYEPSEERDLILNFIKSSSRGIVRGSIDE"
     gene            complement(27527..28367)
                     /locus_tag="ACZPB4_08730"
                     /pseudo
     CDS             complement(27527..28367)
                     /locus_tag="ACZPB4_08730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005803697.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
     gene            complement(28515..28640)
                     /locus_tag="ACZPB4_08735"
     CDS             complement(28515..28640)
                     /locus_tag="ACZPB4_08735"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098337.1"
                     /translation="MKEGARLIPVSEATVVASSSTFVKETEPAAEILAAVVTLNR"
BASE COUNT         8253 a         6344 c         6671 g         7460 t
ORIGIN      
        1 atttgcgcca agcacaatat tttggttatc tccgatgaga ttcatgcgga aatggcctat
       61 cctcagtaca cgcattaccc gttcgcctcc gtatcggata ccgccgcttc ctgcagcatg
      121 actttcatgg caccgagcaa gacgttcaat atcgccggta tcgtgacttc ctacgcaatc
      181 gtacccaatg atcgcatccg ggaagaattt tattctttcc ttgaggccgg agagtttggc
      241 gatggcacga tcttcgctta tacggcgaca accgccgctt acacctatgg cgccgaatgg
      301 ttgcaacaaa tgcgaatgta tatcatggag aatgtgcgtt tcgtggaaga gttcatgaaa
      361 cagcatctcc ccaagataaa agtctaccaa ccccaagcct ccttcctcgt ttggttggat
      421 tgcagggaac tgaaattaag tcaagaggaa ctcgtacacc tgttcaaaga caaagccgga
      481 ctagcgttga acgacggaag tatcttcggc cccgggggag aaggccatat gcgtttgaac
      541 attggctgcc cccgctctgt tttagataaa gcgatgaacg ctcttaaaaa ggcggtggat
      601 aagaaataaa atcgtatctt tgcgagcatt tctatacata tttaaaatac aagacaaatg
      661 aaaattacag caaacaaata cgttgcggtt acatacgacc tgaacgttgg cgaaggtgaa
      721 gaacgtgagt taatggaaaa agcgacggtc gaggctcctt tgaaattcat ctacggaaca
      781 ggcatgatgc ttccggcatt cgagaaagcc ttgaacgggc tggaagtagg tggcacgttc
      841 aacttctcca tcgagccagc cgaggcttat ggcgaatata acgaggagca cgtattggat
      901 cttccgaaga atatcttcga ggtagacggt aaattcgacg ccgagatgat caaggaaggt
      961 aataccgtcc cgatgatgga ttctaatggc aaccgtatga acggctccgt attggaagtg
     1021 aaggatgata tcgtggtaat ggacttcaac catccgttgg ctggcgagac tttgcatttc
     1081 agcggcgagg taatcgacgt acacgaaccg acagcggaag agatcgcagc cttctccgct
     1141 cccgcaggtg gatgcagttg cggttgcgac gattgcggta gcgattgtgg cgataaccac
     1201 gagggtggtt gtggttgtgg tggatgccac taaataatgg gaaattgaga attgaaaatt
     1261 gaaaattagg agaagtgcct aatcatcggc ttttgattct caattttcag ttttcaattt
     1321 tcaattagac aaagcggtga atacttttgg taatatttat agattaacat cgttcggcga
     1381 atcgcacggc cccggtatcg gcggcgtgat cgacggatgc ccagccggga tcgaattaga
     1441 tacggcattc atccagcaag agctgaaccg tcgtaaaccg ggacaatccc gtatcacgac
     1501 cccccgtaaa gaggatgatg aggtacagtt tctttccggt atctacgagg gaaagacaac
     1561 cggcacgccg ataggtttca tcatctggaa caaaaaccaa cattcctcgg actatgacaa
     1621 tatgaaaacg gtttaccgtc cttcccatgc tgattatacc tatcaaacga aatatggaat
     1681 ccgtgatccc cgtggaggtg gacgttcgtc cgcccgggaa acgatagctc gttgcgtggc
     1741 tggggccatc gctaaactcg cccttaagca atacggcata cagattcaag cttatacctc
     1801 gcaggtcggc ccgatccaat tagcgggtag ttaccaagat tatgatttaa gcttgacgga
     1861 ggagagcgac gtacgttgcc cggacccgaa gaccgcctca gagatggaaa ccttgatcgc
     1921 cgaggtcaaa tcaaaaggag atacgatcgg cggtattatt acctgtgtgg cgaaaggggt
     1981 tcccgtcgga ttgggagagc ctgtgttcgg caagttacat gccgcgttgg gacatgcgat
     2041 gcttacgatc aacgccgtga agggcttcga gtatggagac ggattcaacg ccgccttctt
     2101 ccgcggatcg gaaaggaacg atcgcttttt caatgataac gggcatatca atactcgtac
     2161 caataattcc ggcggtatcc aaggagggat ctccaacgga caagatattt atttccgggt
     2221 agcctttaaa tcggtcgcta cgatcttgat ggaacaagaa acggttaaca tggagggaga
     2281 ggatacgata ttaaaggcac gcggacgtca tgatccatgc gtattgcctc gtgcggtacc
     2341 tatcgtcgag tctatgaccg ccatgacttt attggattat ttattgatcc agaagacacg
     2401 ggaaaacttt taagactaat tctatatggc ttggattctg ttaattatag ccggattatt
     2461 cgagatcggc tggccgctgg gctttaaatt agcaagtatg cattccaaat attttatttg
     2521 gtttataggt ttatcgatct tatccatggg cttaagcggt tatttcttat atctcgccca
     2581 gaaaagcatc ccgatcggta cggcttatgt aatctggacc gggatcgggg ctatagggac
     2641 tgttcttctt ggaatcttgt ttttccatga ttccgcaaat atattcagat tattgttctt
     2701 atccttgata ttgataggga tcgtcggcct gaaattagtc cattaatccg ggagaaaaac
     2761 accagtattc gcatagcctc acggcagtat cggtgtgaac ttacgccagt ataggcgtag
     2821 ggctatgcgg ataccggcgt taaacgatgc ggttattcat gatggtaagg ctcgttattc
     2881 aagatcgtca tcgcccggta aatctgctcg ataaagatca atcggatcat ctggtgggaa
     2941 aaagtcatct tgctcaacga gatcttttcc gatgccgcct tatacacggc ctcactaaaa
     3001 ccgtaaggac cgcccaccac aaataccaag cgtttcagaa ccgcatgcat tttcttttcc
     3061 agataagtag aaaattgcat ggaggtgaac tccttccctt tctcgtccag caacaccaaa
     3121 taatcgccgg gctgcaaagc ctttaaaatc aattcgccct ctttctcctt ttgctgcgcc
     3181 tctgagaggt tcttcacgtt ctttatatcc ggtatgactt ccatttcaaa gggtatataa
     3241 tgcgtcaagc gatttttata ctcattgata gcctccacaa aataaccggc atccgtctta
     3301 ccaatcacaa tcagtccaat cttcatctac ttacatttac atgtttagaa aggctaagtt
     3361 acaagaaaaa tacatacctt tgccactaat tactcaataa aataaagaaa gcttatgaaa
     3421 cgactcttac ttacattcgc cttgatattc gcgttcgtat gtgcgcaggc ggcggatatt
     3481 accagtatat caaatgcttt caaggcagga aatgcctcct ctctatccgg tgctatggat
     3541 aaggtggtgg atgtagcctt gcccggttcc tctaagaaat gtaacggaag tgaggccgtc
     3601 tctatgttgt cctcattttt cagttcgaat aagccttccg gattctcggt cgtacatcat
     3661 gcggataaaa aggaaagcgg tttccttgtc ggaaagcttc cgacgtcttc cggtgagtac
     3721 cgtgtaaaca tcacgtaccg tgccgaaggg aatacagcga ttatacaatc aatcagaata
     3781 gaataaaaga tggacaaact tattgacgac ttaatcaaat tagcgtttgc cgaggatatt
     3841 ggcgatggtg atcataccac cttatgttgc atccccgaga cagcgatggg gaaaagccag
     3901 ctgatcatca aggaagatgg cgtattggcc ggcgtggaaa tggctaaacg tatcttccac
     3961 gacttcgatc cggaactgaa aatgacggtc tttatacaag acggagccga agtgaaaaaa
     4021 ggggatatag cgttcgtggt ggaaggtaag atccaatcct tattgcagac cgaacggttg
     4081 atgctgaacg ttatgcaacg catgagcggt atcgctacta cgacccgtaa atacgccaag
     4141 gcgttggaag gtaccaagac acacgttttg gatactcgca agacaactcc cggtatgcgt
     4201 atgatcgaga aagaggccgt acgtatcggt ggcggcatga accatcgcat cggtttgttc
     4261 gatatgatct tattgaaaga taatcatgtg gatttcgccg gcggcatcga gcaagcgatc
     4321 acacgtgcgc aaaactatct gaaagagaaa ggaaagagcc taaagatcga gatcgaggtt
     4381 cgtaacttcg acgagttgga acaagccatg aaagtcggcg gtatcgatcg tatcatgttg
     4441 gataatttca atatcgagaa tacaaaagaa gcggttcgcc gcatcaacgg acgtttcgag
     4501 gtagagtctt ccggtggtat cacgttcgac acattacgtg attacgcaga atgtggcgta
     4561 gacttcatct ccgtaggggc tttgactcac tccgtgaaga gcttggatat gagcttcaag
     4621 gcctgctaaa acgaaaaacg atcattctat aaaaaaacag ccttgagaag atcaacttct
     4681 tgaggctgtt tttcctatat ctaccctatt atcttgattc actatcattt ctgatagaac
     4741 tattatcatt tttaaaacat tgccattcct tcctttcccg tacttttaag aacaaattat
     4801 tcaacctaaa aatagtatca tgaaagaatt gaaaatgttt atagatggca gattcattga
     4861 gaatgagtct gggaaatgga tcaaggtatt gaatccttct accgaagagg ttatttcact
     4921 gatgcctgac gggacggttg aagatgccag aaaagcaatc gatgccgcag agaaagcgca
     4981 gaatcaatgg gaaagaacac cctctataga aagggcggct tatctgacaa agatagcggc
     5041 aggcatccgt aagagagaga aggaactgac cgacatcatc gtccgtgaag gaggcaaaac
     5101 ccaaggactc gccaatgttg aagtcctttt taccgcggac tatatggatt acatggcagg
     5161 ctgggcccgc cggtacgaag gggaaatcat tcccagtgac cgccctcatg aaaacatttt
     5221 cttatttaag agaccgattg gagtaacgac aggtatccta ccttggaatt tcccattctt
     5281 tctagtcgct cgtaaagccg cgccggcctt gatcaccgga aatacgatcg taataaaacc
     5341 tagccagctt acgccagaga acgcatatgt attcgcgcag atcgtggagg aggcaggttt
     5401 gcctgccggc gttttcaatc tagtaaatgg acggggtagc gtgattggtc atgaactctc
     5461 ggcgaatccg aaagtaggca tggtaagtct gacaggaagc gtgggagccg gacaacagac
     5521 catggcagcc gccgctccta atatcacgaa agtttctctg gagttaggag gtaaagcccc
     5581 ggctatcgtg atgaaggacg cagatgtcga tctcgccgtt aaatccatta ttgcctctcg
     5641 tgtgatcaat accggacagg tatgtaattg tgccgaacgg gtttatgtag acaaagcgat
     5701 aaaagagacc ttcatggaaa aactagtcgc cggcatgaag caggtaaaag taggaaaccc
     5761 caatgagatc gcggatctgg atatgggacc tcttatcgaa gccagtgcgt tgaagtctat
     5821 ggagaaaaaa gtagaaagag cgatccagca aggtgctagg ctactgtgtg gtggtcatag
     5881 gatcggtaca aaaggatatt tcttcgaacc gaccgttttg gattgtgtta cgcagaaaat
     5941 ggatatcata caagaagaga cttttggccc cgtgctaccg gttgtcgaat attcggacat
     6001 caacgacgct atcgcatggg cgaatgattg cgaatatgga ttgacttctt ccgtatatac
     6061 acaaaacttg aataacgcat tcaaggtaat gcgttcctta aaattcgggg agacttatat
     6121 taaccgtgag aattttgagg ctatgcaagg cttccatgcg ggatggcgta aatccggaat
     6181 cggtggtgcg gacggaaaac atggacttga ggagtatttg caaactcaag tggtttatct
     6241 tgagacaaag gaataaaaaa taagactaaa gatcccttct tgggatcttt agcatatcta
     6301 cttaatctaa cgtcaaatta aactcatccc tcaaacgacc caaggtagga tttatcttca
     6361 tcagcagctc tagcttctcc gtggatgtat aagccaagtg cttctcattt ccctctacga
     6421 tccggacacg catctggata cggctgttat taagatgctg gcggagaaat ggcaggatat
     6481 ggatcgcatt attgatcaat tcctcttgct gccccgggtt atgtacggct acctcgaaat
     6541 aataattctc ttgcaaggta ggcttgcaat tgatcatcgt attcttaaga tacactttct
     6601 tgtcaatcgt tgcggcgtaa ttatcccatt cacgaaccaa ggaatcattg tcaaagggag
     6661 ttactacctc ctttacgttc gttgtcgctt gttgaacggt ttgttgctta ggcttctcca
     6721 ctccgatctc cttcatggag atccccatcg gacgagccgt tctacgagcc ggattaggcg
     6781 ctgtagacgg aggtggcgca ggaaccgagc tcggcatgtg cgtactcata acttgtggag
     6841 caccggccgc tgccgtaact gaaggagctt gaggcggctg ttggggctgc ccgctattca
     6901 ccgcttgaga agacggattc gtcccagcaa tcggctcaat taacgctttt tttttatcgt
     6961 caacggccac ctgtgttaat tgacagatct gaatcaacgt caattccaat aaaagacgct
     7021 tattgcggct ggcacggtaa ttcaaatcgc acgcattcgc tagctctatc gccttgaaca
     7081 gaagttgatc cggacaatgt ttcgccatct ccttatatcg ttcccgtata gaagctccca
     7141 cctcgaatag caccaaggtg gactcatccc ggcataccaa taagtcccgg aaatgcccag
     7201 ccaaaccggt tatgatattc tgcccgtcga atcctttgcc taatatctca ttcaagatca
     7261 ataaagatgc ccgcacattg ccggataaga tcgcatccgt cagacgaaaa taatactcat
     7321 aatccagcac gttcaagtta tcgataaccg cttgatacgt gatatttcca ttcgtaaaac
     7381 ttaccacttg gtcaaagata gacaaagcgt cgcgcatacc tccatccgct ttctgggcga
     7441 tcacgttcaa ggcttccggt tccgctgtta ccccctcttg cgaagagaca tattgcaaat
     7501 gctccaccat gtcggcgatg gatatacggg agaaatcata gatctgacaa cgggaaagga
     7561 tcgtgggaag caccttgtgc ttctcggtcg tagccaagat aaagagagca tgatgcggag
     7621 gttcctccaa tgtcttcaag aatgcgttga aagcggcggt tgtcaacata tggacctcgt
     7681 caataatgaa gactttgtat ttaccgattg gaggcgggat acgcacttgg tcgatcaagg
     7741 tacggatatc gtccaccgag ttattcgagg cggcatccag ttcatggata ttgtaagaac
     7801 gctgctcatt gaaagcccgg cacgactcgc acgcattgca agcctcgcca tccgccgtcg
     7861 gattcaagca attgatcgtc ttcgcaaaga tacgggcaca cgaggtcttt cctactccac
     7921 gaggaccgca aaacaggtaa gcatgcgcta atttgttact ttgtatcgcg tttttcagcg
     7981 tagtggtaag agacttctgc cctactacac tccgaaaagt ggacgggcga tattttcttg
     8041 ccgatacaat ataattatcc attctctgct ttttattgat aagacaaaga taaacaaaat
     8101 aattcattat cttcgcgaaa acgatgtttc gatgtcacgc ataaaagagt tttacataaa
     8161 gtatctatcg tggatcaacg cttattggtt ggttaccatc gtgttcctta tcgtcacctt
     8221 tacggtgggc gatagcagcc tgtataaacg ctatacgtac gacgagaaaa tacgcggctt
     8281 ggagaaagag atcaaacatt accaaaagga gatcgaaatc aacagcaaga aattaaacga
     8341 cctgcatacg gacaaggagg gactggaacg tttcgcccgt gaagagtatt ttatgaaaag
     8401 gtcgaacgag gatgttttta ttatcaagga caaataaatg aatcaacaaa tcagatcgat
     8461 tattttcggc gtagcgggat tactcgtatt agccggtgcc gtattgtttc ttactcattg
     8521 ggctatcgcc ccttatttat tcgctgtcgg tgcggcgggt atagccgttt gctatctgac
     8581 ccttccggtt aaggacttgg actttcgtcg ccgtcggctc caccgtttca acgtattcgc
     8641 cggacttcta atgatcgtat cttccggctt tatgttcaac aaccgtaccg agtggatcct
     8701 ttgcttgagc gtagccgcta tcttacaagt atataccgct ttcgttactc ctaaagagta
     8761 attggccgca aaacgcagtc tcgaccgatg aatatatact gaccaggcca acgcagtata
     8821 tattactttg cagatacagt atatcttcta taaaatcccc ggtaagtacc gttaaaaaag
     8881 ggtgtatcaa acgttccttt gatacaccct ttcttttata aattctatta atagcttact
     8941 tggccggaga ggaataattc ttattcaagt attccagcaa ttcgcctgtg atatcatagg
     9001 aatcgccagc caaaaggata ttatctccta ccgtattgct gaataccact tgatagcccc
     9061 tacccagatt gaaagccttc aattgagaaa caaccgtatc gcgtaattgc tcgttcaact
     9121 tctgctgctc ttgcatcaac tcttgagcca attggttatc taagttctgc aactcttgtt
     9181 gcttattcaa taaacgttgt tgctcttgct ccgccctctc acgggtaagg aaagcgttat
     9241 tttctacctt acgctggaaa tcttgcatct cgccttgtaa actacgggct ttctgggtga
     9301 tgttagcacg ggaattctct tgtttcttca agatgatctc gttcagatcc ttggaataat
     9361 tgtaattaag taacagggaa tccacattta cataagcgat cggaagtaag gccgttgtgt
     9421 ctcccgctga cgcgaatgtt cttgttacgc ttgattcttt cttgccggaa aattgcataa
     9481 tatacaagat tacgacagcc accgctagca caccgttaat aacgtagtta atgttcttca
     9541 taaagtgcaa tttaaatctt atttttttat tcttttattt cgttcatgat gtcatagagc
     9601 cccttttgct taaccgccat acgatccatg gtcttcgcgc aaaatatacc tttcttaccc
     9661 aacgccctgt ttccttcgat atgcgtattc gggaaccttc ctcccttttt caacagcact
     9721 tttatcgata gcaacacgac gctgataaca agaattatga ccgtaaataa taacgttgta
     9781 agcattttct ctatatttgt ggacgcaaat ataagagttt aagtgattac taagtgtctt
     9841 tttggcattt tattctactt tttttcgaac taagctcttt cagttgcggt tttattaact
     9901 ttagagtaac atctataata cattgtaaca ttatgaagat tactgattta aagcctacta
     9961 tcgtatggaa gttcttccat caagtaaccc aagtgcctcg cccctcaaaa aaggaaggca
    10021 aaatgattga attcctagaa tcattcgcga aagagtacaa aatagctatc aagaaagatg
    10081 aagccggcaa ccttttaatg tcaaagcctg ccactccggg aatggaggat cgtccggtag
    10141 tcgtattgca gtctcacatg gatatggttt gcgagaaaaa taacggtacg aaacacgatt
    10201 tcgacaatga tccgatcgag acgatcgtcg acggcgaatg gctgcgtgcc aacggcacta
    10261 ctttgggagc cgataatggt atcggtgtag cggccgagtt ggctttgctt gcctcagatg
    10321 atatccaaca cggtccgatc gaatgtttgt tcacggtaga cgaagaaaca ggtttgaccg
    10381 gagcgaaagc cttgaaagaa ggtttcatga ccggagatat cttgttaaat ctcgatagcg
    10441 aggacgaggg agagatcttt atgggttgcg ccggaggtaa agacacgcaa gcgactttcc
    10501 attacgagcc agttcctacg tccgataaga tgcagtattt ccgtatcgac gtgaaagggt
    10561 tgaatggcgg tcactccggt ggcgagatcc acaaaggatt aggcaatgcc aacaagatct
    10621 tggttcgttt cttattctta ttgaaaaaga aatatgattt cgttctttgc tctatcgatg
    10681 gaggaaactt acgtaacgca atcgctcgcg aggcacacgc cgtgatcggc ttgcatccgg
    10741 aaaataagga ggatgtacgt atcttgctga accatttcgc cgccgacgtt gaaaatgagt
    10801 tgaaacatgt agacccgaac gttcagttag cgatggagtc cacggatcgt ccggagtatc
    10861 atatcgacaa tgccaccgcc gagaaattaa tctacgcctt gcacgcttgt ccgcacggcg
    10921 taatcggtat gagccacgat atagaaggct tggtagagac ttctaccaac cttgcttccg
    10981 taaagatgaa agaaggcgat acgatcttgg tcggtaccag ccaacgtagc tctatcgaat
    11041 catgcaagat cgctatcgcc aatacggtag cctccacgtt cctattggct ggagcagatg
    11101 taaaacatgg cgatggctat ccgggatggg ccccgaaccc cgactctaag atcttgaaga
    11161 tcgcacagga gacttacaaa cgcctattca acaaagacgc caagatcatg gccatccacg
    11221 ccggattaga gtgcggtttg ttcttggaaa aatatccgaa actggatatg atctctttcg
    11281 ggcctacttt gcgtgacgta cattcaccca acgagcgtat cgagatcgct acggtcggtt
    11341 tatggtggag ccaccttctt gaattattaa agagcatccc cgcaaaataa accaacgttt
    11401 tttgcgttat aagaagagga aagacacgat aaccgtgtct atcctctttt tttatgttaa
    11461 tgtcttgcaa cttttttatg ataattttgt ttatctattg aaacaagaac acaagatatt
    11521 tacagttaac atttacgaaa atgaaaagat taacgataac gctatttata cttgcgacgc
    11581 ttctgttgaa catgcttccg gcatgcgacg gtttggatga tcattattcc actaacccga
    11641 cttaccggct aagcttctcg acagacacgc tcgcttttga cacgatcttc agtacgatcg
    11701 gttctaccac ccgtcaattt atgatctaca ataaaaatag tgaacctctg agcattgagt
    11761 ccatcatgct ggccagtgga gagtctaccg gcttccgcat gaatgtggat ggacgcaaag
    11821 gtagctcatt taataatgta gggatactcg ccaacgacag catgtatgta ttcgtggaag
    11881 taacggtcga tccgaatggg ggcaatcaac ctctgttgat acaggattcc gtacttttca
    11941 ccgtgaatgg catccgtcaa tccgtattat tggaagccta tgggcaggat gttaatcttt
    12001 acaaaggcgg tgttacgatt acaaaagatt ctatcctcac ggccaatcgt ccttatttga
    12061 tctacgatag tttggttatc gctaaagggg tttcattgaa tatcgagaag ggggctactt
    12121 tctatatgca tgataaagcg agcctgatcg ttcacggctc catgaacgct ttaggcacct
    12181 tggatgagcc tatcactttc cgaggcgacc gtttggatta tatactaaat gatatattac
    12241 cgtatgaccg gactcccgga caatggggag gcattacctt taaggcggat agctacggga
    12301 atgtctggga taatgtaatc gtacgtaatg gtacctccgg tgtatattgc gagccttcca
    12361 ccccggaccg gccaaagatc aagataaaca actcacagat cacgaatatg gggagcgatc
    12421 tattcttcgc catcaattgt gatgttatcg ctacaaatac ggaattcagc aatgccggag
    12481 gaagtgtact cactttagtc ggtggtaaat attacttcgc tcactgtacg atggctaatt
    12541 acatgagttt aaccaaaagg gaaatggcca gcgagactgt tcctttggat agtaaatgcc
    12601 tgtacttgct caataacgta acagtagacg gaaatggccc gtatcctatc acgcaagctt
    12661 attttgacaa ttgcactatc gatggaagtt acgatgtcga attaaaagca gatggcagta
    12721 cagatttcga ttatcggttc aatcactgtg cgcttaaagc caaagaatcc tccagcgatc
    12781 acttcaagga ggtcttgttt atcaaaaaga ctccttccta tcggaaagta ggaggcaagc
    12841 aaaataaata cacctatgat ttccggccag attccgtatc gactaccgga gtcggaaaag
    12901 cagatcccga gataacgaag aattatccga tcgatcgtta cggtgtcaac cggctaacca
    12961 gttcgaacgg cccgaccata ggagcctacg agtttgttca ggaagagacc gaagattcaa
    13021 acgaataaga atacattaca tattaacaat taatcaaagc tttaactatg aagattttta
    13081 tgttttttct tttattcttt gcctcccctc cgttatttgc ccaagctacg ttcaaggtca
    13141 tgacctataa tgtggagaac tttttcgaca caagggataa tccaaccaag aatgacgatg
    13201 aatttctacc ttccggcaac cggtactgga cacaaagccg ctactatcat aagctacaac
    13261 aaatagcgaa agtaataagc gctgccgggg aatggagcac accggcctta atagctcttt
    13321 gcgaagtcga gaatgactcc gtcctgtctc atcttacccg tcgcacaccg ctccgctggc
    13381 aggattaccg atatattatc actcaaagcc ccgatcccag aggtattaat gtcgctcttc
    13441 tttatcaacg aaatcaattc ttttatttac gacatgaatc cattccaatt cgtttttccg
    13501 ggaacaaaca caaattaacc cgagatatcc tacacgtata tggaaagatc ataacaggcg
    13561 ataccttaga tgttttcgtg tgtcatttcc cctcccgcta cggaggagaa aaagaaagtg
    13621 aaaaggatcg ttttgacgcg gcccgcactt tacggggatc tagcgattcc ctgttactga
    13681 tacgagaaaa accgcagata ctcattatgg gagacttcaa tgatacccct caagacagaa
    13741 gtatttccga gatattcgct gcccaagcct ttcctgaaaa tacgcagatc acagattcca
    13801 catcttgtac ctattataat ttgttcgcaa gcccccatat aactcaattc ccgggtagtc
    13861 ataaatacca aggcgaatgg agccaactcg atcaaataat cgtaaaccgg gatctcatca
    13921 cgcaagagtc ttccatgcat atcattccgg aaagcatcca catattcgct cctgattttt
    13981 tattgactaa ggataaaaca tggcgggggg tacgtccttt tcgaacctat tacggcttta
    14041 aatatgaggg cggttttagt gaccatttac cattaacagt cgattttcta atacgttctc
    14101 agatcaaacg ctgaaaagaa aaccttgaaa ccttttttcc gatcccttgt tatcctatta
    14161 aagaagaaaa gctatgtagt caacaagcaa acagaacaca tatggaaata aatctcgcct
    14221 caatccggca agaatacaca aaaggaggat taagggaaag cgaacttccg gataacccat
    14281 tcttgctttt cagtcaatgg ttacaagagg ctatagacag caaagtagat gaacccacgg
    14341 ccatgctagt agggaccgta tctccagaag gcaaaccttc cacccgtacc gtcttattaa
    14401 aggacctgca tgatgataag tttattttct actccaacta cgaaagccga aaaggcaggc
    14461 aactggcaca aaacccggca atctctcttt cgtttgtatg gcatcaatta gaaaggcagg
    14521 tacatatcga aggtacggct gaaaaagtcc ccccggatga atcggatcaa tatttcaaaa
    14581 aacgcccgta taaaagccgg atcggagctc gtatatcccc acaaagtcaa cccatcggca
    14641 gccgtatgca acttatacga gctttcatta gagaggcagc tcgttggatt ggaaaagaag
    14701 tggagcgtcc ggctcactgg ggcgggtatg ccgtcattcc tgaacgtatc gagttctggc
    14761 aaggtaggcc caaccggctt catgatcgca tagtatatac ccttcaaccg gacggccatt
    14821 ggaaaaaaga aaggctcgcc ccatgaaatc aggaacaagt ccgataccaa aggataagag
    14881 atagataatt catcgaaaac gattatcttt gtctgtcaaa atacgtaata cctatgaata
    14941 ttagatccat atatctagcc ggtctattcg cgatcatcgg ctcccacata atcaacacaa
    15001 acgcccagca acttaggaat cctttcgatt tcccgatctt actgagcggg aacttcggtg
    15061 agttaagaag caatcatttc cattccggaa tagacttcaa gacacaaggg gtagaaggta
    15121 aacccgtaca tacggtacaa gaaggatacg tatcacgtat atccgtaagt ccatggggct
    15181 acggtaacgg gctttacatc acacacccgg atggaacgac caccgtatac ggccatctac
    15241 aaaaattctc gaagaaaata gcgaattatg taaaagagca acaatacgca caagaaagtt
    15301 tcaatgtaaa tctcttcctt acgccggatt tgcttcctgt cgagcaaaat gaagtcgtag
    15361 cgttaagcgg caataccgga agctctggtg gacctcatct ccattttgag gtacgagaca
    15421 ccgagaccga ggaagtcatg gaccccttgg attatttctc ggatcggata accgataccc
    15481 gtcctcctaa aatccaagga atacagatcg tccccatcga aggaaaaggc gtagtaaacg
    15541 gcaaaagcaa gaagcttgag ataaaacccg tcacggcgaa aaacgggaaa cagacaatca
    15601 ctggaaaaat cgaggcatgg ggagaaatag ggctcgctgt aaaagcctat gattatatgg
    15661 ataatacgac taacatttat ggcgtacgag aaatcacgct cacggcagac agccaagtga
    15721 ttttccatag taatctcgat aagttcgcat ttgacgagac ccgttatctg aacacattca
    15781 cagattacga agaatggaaa gatcatcgct ctttctatat gcgtagtttc atcgagccgg
    15841 gaaaccgtct acgcttcctt gaaagcgtaa accggggaat cttgcgtata gatgaacctc
    15901 gtacctatca tttgacgtat acacttgctg acgctttcgg caatgccacc cgtttatcca
    15961 tctggatcga gggaaagaaa caagagatcc cccagatcga tacgactcat acagaattat
    16021 tccattgggg tggcgagaat aggttcggcg ctaaaggcat ccgtctcgtc atgcctaaag
    16081 gtaatctata taatgacctc tacttccgct attcggtgaa agaagatagt acctcattat
    16141 cagccaccca catattgcac gataagccaa tccctttgca tggaacggcc cagttatcac
    16201 tattcttgca aagcgatacg cttgagaata aacaacaata tggtgtggtt cgcttacaaa
    16261 acggacgtgc ctcttggatg ggcggtacat accgtaatgg ctggatcgac gcaaatatca
    16321 aggaattggg cagttataag atacaacaag atacaaaggc tccggttatc acgccgatca
    16381 accaacagac gtggatcaac aaacagaact tcatattccg tttgtccgat aacttaagcg
    16441 gggtacaaac ctaccgggga gaaatagacg ggcagtttgt cttattcgag atgaataata
    16501 aatcggttat tacctatcgc ttcgataaag aaagactgca aagaggtaag cacgaactta
    16561 aattaatcgt aacggatgct tgcggaaatg agtcgattta tacacatccg ttcacgtggt
    16621 agaacgattt atcgcatttt ttaggcaaaa tataagtcct ttgattgctt tactttaaga
    16681 aattcgtata tttgtttctt gtatatttat cgtattgagt agattgctca acaataaaca
    16741 caataatatt ataaacatgg aaaacaacga cttattagaa atggtaagaa gtaaggcaca
    16801 aggatggctt acgaaaagtt atgatgcgga aactcgtgct caagttcaag cgttacttga
    16861 caacgaagat cctactgagt taatcgagtg tttttataaa gacctagaat tcggcacagg
    16921 cggattgcgg ggaatcatgg gagtaggttc aaatcgtatg aatatatata cggttggcgc
    16981 ggctacccaa ggtttatcca actatctgaa aaaggaattc gcagatcttg agcagataaa
    17041 ggttgtcatc ggtcacgatt gccgtaacaa cagccgtaaa ttcgctgaaa tatcagccga
    17101 tatcttctcc gctaacggaa tcaaggttta tttattcgaa gacctgcgtc cgactccgga
    17161 aatgtcattc gctatccgta aattgggatg ccagagcggt atcatcttga cggcttctca
    17221 caatccgaaa gaatacaacg gatacaaggc ttattgggat gatggcgcac aaatgatcgc
    17281 cccgcacgat aagaatacga tcgccgaggt taacaagatc cgtaacgcta gcgagattaa
    17341 attcaaagga aataaagaat tgatcgagat catcggacaa gcgatcgatg atgaatatat
    17401 caaggaatta acaacgattt ctttgtctcc ggaggctatt tcccgccata aggacatgaa
    17461 gatcgtgtat actccaattc acggaacagg tgttaaattg gttcctgccg ctttgaaagc
    17521 ttacggattc acgaacatta tccatgtacc ggaacaagat gttgttagcg gtgattttcc
    17581 gacggttatc tctccgaacc cggaagagcc ggctgcttta gctatggctg tagagaaagc
    17641 aaaagagact gacgctgaat tggtaatggc ttccgatccg gacgcagacc gtgtaggtgc
    17701 cgccgttaag aataacgaag gcgaatgggt acttttgaat ggtaaccaaa ccgctttgat
    17761 gttcgtttac tatttaatca cccgctggaa agagttaggt aagatcaatg gtaaagaata
    17821 tatcgtaaag acaatcgtta cgacagagac gatcaagacg atcgccgagc gtaatggcgt
    17881 agaaatgtac gatgtttata caggcttcaa atggatcgct aacgttatgc gtgagaacga
    17941 aggcaagaaa aactatattg gtggtggcga ggaaagctac ggattccttt gcgaggattt
    18001 cgttcgcgat aaagacgctg tttccgcttg cgttatctta gccgagatcg cagcttgggc
    18061 aaaagatcaa ggtttgagtt tgtatcaatt gcttcagaag atttacgtgg aatacggctt
    18121 ctctaaggag aaaggtatct ctgtcgtgaa gaaaggcaag agtggagcgg aggagatcga
    18181 ggctatgatg aaaaagttcc gtgagaaccc gttgacagag atcgcaggct ctaaggtaac
    18241 ttatttctac gattactcta cattgaaagg taaggactat gcggagaacg aaaccgttac
    18301 attagatatg cctactacct ctaatgtgct tcaatacttc acggaagata atacaaaagt
    18361 atctatccgt ccttccggaa cagaaccgaa gatcaaattc tattgcgagg ttcactccaa
    18421 ggtaaagagt atcgatgaat tgccggaggc agagaaagcg gcagaagaaa agatcaatca
    18481 gatcaaggct tctttaggga tctaatcgaa tttaattatt acatatagag gcaagggcga
    18541 gaatcgttct tgcctctttt tattctatca gatcaaatca gacttactga aacaaaacgg
    18601 caacaaggcc gtcgcgctcg gaacgagata cgcttcctct tttccacaaa gaaggacttt
    18661 cataggtttg ttataacgtt gctcggtttc caacatcact tgccggcagg caccacaagg
    18721 cgtgataaga tccacacgtt ccccatcctt catagccgcg atcgccaaaa tctgaactgc
    18781 cgcatccgga taacgtgctc ccgcataaaa taaggtggtc cgctctgcgc aaagcccaga
    18841 cggataggct gcgttttcct gattatttcc ggaaagtatc tccccattct ccaatagaac
    18901 cgccgctccc acatgaaact tggaataagg agcataagct tttttcgagg cttcaaaagc
    18961 ggcctcgtac aattgcctat atatattatc caattctcct accgcataga cctctacccg
    19021 ggtctctaat ttcaattctt tcattttctt gattgtttta atgttttgaa agaaacataa
    19081 ctataattct tataggctat aaatataaaa agaatatatt aatttcgcac ccacatcata
    19141 gaatatacct taatatagaa caaagacata tgcattcaat gcttcttaca tccgataaag
    19201 acccgatggg cgccgctatc atcgattatc tcgcacatgg aaaagcgagc aaactccgtg
    19261 tattctcctc catgttcgat gaagatgaga ttcccgtgaa tcaattattc cggactttcc
    19321 aagaaatgcc ctccttggaa cagaaagccc ttcaactcag tacaggcaaa atattggatg
    19381 ttggtgccgg aagtggatgc cacaccttgg ctttacagga aatgggtaaa gaggttaccg
    19441 ctatcgatat atcccctctt tccgtagagg ccatgaacaa acggggcgta aaagacgccc
    19501 gcttacagaa tttttttgac aagagcttaa ccggaccatt cgataccatt cttctcttaa
    19561 tgaacggttc tgggattatc ggtaaactgg aaaatctccc ggctttcttt caccgcttaa
    19621 aagaggttct agcccgggac ggacagcttt tacttgactc tagcgacttg agttatttat
    19681 ttgaagatga agacgggaat ctggatatcg cccccgagga tgattatttc ggagagatcg
    19741 atttccgtat gcaatataaa agtatcaaag gggattcatt tgattggtta tatatagatt
    19801 tcaacacgct gaatctatac gcaaggcaag ccggctttaa agcggaaaaa atagaagatg
    19861 gggagcatta cgattatcta gctcgtatct cctattttta acccatcaat tctcggtaga
    19921 tatgtatttt cttttatata tttgtccggt aaaatcggat cgaaaagaac agttatgcgt
    19981 ttatcccttc attttttagg tatattatta ttgtccctcg tctgtttaag cgcaggggcg
    20041 gaaagccagc ggaagctgac ttcctatcaa aaatacatca gtaaatacag tgatttggcg
    20101 attcaacacc aaaagaaata tcgcattccg gcaagtatca ccttagcgca aggattactg
    20161 gaatccggag ctgggcaaag cgacttggcc agacgctcca acaatcactt cggtatcaaa
    20221 tgccattcgg actggcgagg cggcagggtc tatcacgacg acgacctgcg gggagagtgc
    20281 ttccggaaat acaaacgagt agaggattct tatgatgacc attcccgctt cctcgccgaa
    20341 cgctcccgct acgaacgcct gttcaaatta aacatcaagg attacaaagg ctgggccaaa
    20401 ggactacaaa aatgcggtta cgccaccgat cgtgcttacg cgaataaatt aatcaaggtt
    20461 atcgaagatt atgagttata ccgctttgac tccggtaagg gaacaaagaa gacctctacc
    20521 aagaagcaaa atcttccggt gttcaattat caagtctatc gtacccacgg tttgatctat
    20581 gtatacgcta aggataacga cagtttcgac cagatcgccc gaagcatggg attcaaggcc
    20641 aagcagttga tgaaattcaa tgaggtgccc gaggacttcc cgttgcaggc gggcgatatc
    20701 gtatatctgg aaaagaaaaa gaagaaagcg gacaagccga attacgacca cgtggtacaa
    20761 gtcggagagt ctatgcacag tatcgcgcag atgtacggaa tccagatcaa gagtctgtat
    20821 aaaatgaata aaaaagacaa agattacatc ccggaggaag gagatgtctt aaaacttaga
    20881 taagtaacat aaaaaagtat tacctttgcg gttcaaataa tatagtacaa tgagtgatca
    20941 acgttataac ctgcgaggcg tttccgcttc aaaagaagat gttcacaacg cgataaagaa
    21001 catcgataag ggaatttttc cgaaagcgtt ctgtaagatc atccccgata tcttaggcgg
    21061 tgatcctgaa tattgtaata ttatgcatgc ggatggcgcc ggtaccaaat cgtccttggc
    21121 gtatatgtac tggaaagaga ccggagatct ttcggtgtgg aaaggtatcg cccaagacgc
    21181 tcttatcatg aatatcgatg acctgctttg tgtaggtgcc gtagacaata tcttggtctc
    21241 ttctacaatt ggacgtaaca agctgttggt tccgggcgag gtgatctcgg cgatcatcaa
    21301 tggaacagat gagttgctgg cagagttacg tgagatgggc gttggttgct atgcgacagg
    21361 tggcgagacc gcagacgttg gcgacttagt tcgtaccatc atcgtagata gtacagtcac
    21421 ttgccgcatg aaacgttctg acgtaatcga caataagaat atccaaggag gagacgtgat
    21481 cgtaggtctg gcatcttccg gacaagccac ttacgagaaa gaatacaatg gaggtatggg
    21541 tagtaacggt ctgacctctg ctcgccatga tgtcttctcc aagtatttag cgcagaaata
    21601 tccggaaagc tacgatgccg ccgttcccga agaattggtt tactccggag gattgaaact
    21661 tacggataag atcgaggaat tagggataga cgccggaaag atggtgcttt cgccgacacg
    21721 tacctatgcg ccggtaatta aggtattgct tgataaacta cactctcaaa tccatggcat
    21781 ggtacattgt tcgggagggg cccagacaaa agtcatgcat ttcgtagaga acaagcgtgt
    21841 aactaaggac aatctcttcc ctatcccacc gttattccgc acgattcagg agcagagcgg
    21901 tacggactgg agcgagatgt acaaggtatt caatatggga caccggatgg agatatacat
    21961 cgctcccgag catgcggaag aagtaatcgg catctcaaaa agctttggta ttgatgcgca
    22021 aatcgtgggt ttcgtagagg aagctgataa aaatgaattg attatcgaaa gcgagaaagg
    22081 tcgcttcacc tattaataaa gataaatggc cgaaaatagt ttacttggta aattagacgg
    22141 attagtgagc cgtttcgagg aagtcggtac gcttattacc gacccggcgg tgatcgccga
    22201 catgaaacgg ttcgtaaaac tgaacaaaga gtaccgtgat ttggagaaaa tcgtgggagc
    22261 tcgttcggaa tacgtgaaag tattgaacgg gatcgaggaa gcgaaagcct tgcttgagtc
    22321 cgagcaagat ccggaaatgc gggaaatggc tcgtgaagag ctggatacct gcaacgaacg
    22381 tattcccgct ttggaagaag agataaaatt attgctcgtt cccgctgatc cgcaagacga
    22441 caagaacgcg atcgttgaga tacgaggagg aacgggaggt gacgaagccg cccttttcgc
    22501 cggtgatcta tatcgtatgt acgtgaagta ttgcgaactg aagggatgga aaataagcgt
    22561 gtctagcttt agcgaaggct catccggcgg ttttaaggaa atcatcttca cggtatcggg
    22621 cgagaaagta tacggtacgt tgaagtatga gtccggtgta caccgtgtac agcgtgtacc
    22681 ggctacggag acgcaaggac gtgtacatac ctccgccgct acagttgccg tattgcctga
    22741 ggcggatgaa tttgatgttg agattaatga aggggagatt aaatgggata ccttccgctc
    22801 cggtggggcc ggtggtcaga acgtaaacaa ggtggaatca ggtgtccgtc tgcgttatgt
    22861 ctggaagaac cccattacag gtgtgagtga ggaaatcttg atcgaatgta cggagacacg
    22921 agaccagccg aagaacaaag aaagggcgct tacccgtctt cgttcgttta tttatgacaa
    22981 ggaacaccag aaatacctag acgatatcgc cagcaagcgt aagaccatgg tatctaccgg
    23041 tgaccgttcc gcgaagatcc gtacgtacaa ttacccgcaa gggcgtatca cggatcaccg
    23101 tatcaattac acgatctata atctttcagc ctttatggac ggcgaaattc aagattgctt
    23161 ggatcacctg atcgtagcgg agaacgctga gcgattgaaa gagtctgaat tgtaaacaca
    23221 tccaatcatt tcatactgaa aagaaaatga acaaacaaca gctattcgag aatattaaaa
    23281 agaaacaatc cttcctttgt gtcggattag atacagatat aaaaaagatc ccgcaacatc
    23341 tattgtcgga agaagatcct attttcgcgt tcaataaagc gatcatcgac gctaccgccg
    23401 attattgtgt cgcttacaag ccgaatctgg ctttttacga gagccttggt acaaagggca
    23461 tgatggcttt tgagaagact gtggcttact tacgggagaa ttatcccgat caatttatca
    23521 tcgccgacgc gaaacgtggc gatatcggaa atacctccga gatgtatgcc cgttctttct
    23581 tcgatcatat caaggtagat gccgtaacgg tcgctcccta tatgggcgag gatagcgtaa
    23641 aaccattctt gatctacccg gaggcttggg taatcttatt ggccttgacc tccaataaag
    23701 gctcacatga ttttcaaatg acggaagacg cgaatggtga acgtcttttc gagaaagtat
    23761 taaagaaatc gcaagagtgg gcaaccgacg agcaaatgat gtatgtagtg ggcgctaccc
    23821 aaggcaagat gttccttgat attcgtaaac aggccccgaa tcatttcttg ttagtcccgg
    23881 gcgtgggcgc tcaaggcgga agcttggcgg aagtagctca atacgggatg aacgaccaat
    23941 gcggtctttt ggtaaattct tcccgtgcga ttatttacgc ggataagacg gaggctttcg
    24001 ccaacgtagc ccgtgaggcg gcacatgccg tacagaaaga aatggccggt tatctacatg
    24061 ataagggaat tattccctgc aaagcatagg ctatataaag aattttcacc atttttgcaa
    24121 actaactgtc tataaacagc ggacagtcaa cgaagataca tatataattg aataagtaat
    24181 ggagttttca gcccaacaaa ttgccggctt cctgaacgga acgattgaag gagatccgaa
    24241 cgttaaagtc agcaacttct ctaaaataga agaaggaaag ccaggtacat tgaccttttt
    24301 ggcgaatctt aaatatgcgc atcatattta taataccgag gcaagcattg ttttggtgaa
    24361 taatgatttc aaaccggaac aaccgataag agccacactt gtaaaagtag agaacgctta
    24421 tgcggcgctc gcgatgttat taaatttggt agagcaatcg aagagcaaaa agaagggggt
    24481 tgattctacc gcttttatcg ccgcttccgc gaccgtgagc gacgattgtt atgtcggtaa
    24541 cttcgcctac atcggagaag gcgtaaaaat gggtaagaac tgtatggtat acccgcacgc
    24601 ttatatcggt gatcacgtga cggtaggaga taactgcgta ttctatccgc atgccaccgt
    24661 ttacgagaat tgtacaatcg gcaataattg tatccttcat gccggtagcg tagttggagc
    24721 cgacggtttc ggattcgctc ccgaaggtga gacttacaag aaaatcccgc aattaggcaa
    24781 cgttattatc gaggatgatg tagagatcgg agccaatacg acaattgacc gtgcggtgat
    24841 ggattctacg atcattcgcc gaggcgttaa gctggacaat ctcgtacaaa tcgctcataa
    24901 cgtggaggta ggcgagaata ccgtgatggc ggcgcaagtc ggcatcgccg gttccgtaaa
    24961 agtaggaaag cattgtatgt ttggcggaca agttggtttg gccggacata tccatgtggc
    25021 ggaccacgtc gtattcggag ctcaggctgg cgttatcagc gacgtgaagg aagcgacgac
    25081 attgctcggg gcgccggcga tcaacgctaa gaactttatg cgttccagtg cgatcttcaa
    25141 ccgtcttccg gatatatacc gctcgctggg gcaaatgcaa cgggaaatcg aacaactcaa
    25201 gaaagaaatt aataaacaat aaagacctat gcaaaaacag aaaacgcttg cggcaagttt
    25261 ctccttgaaa ggaaaagggt tgcataccgg attagatata gagattacgt ttaatcccgc
    25321 acccgagaac catggataca agatcaaacg tgtcgatatg gaaggccaac cgacgattga
    25381 cgccttggcc gaggacgtgg ttaatacaca gcgaggtacg gtgcttagca agaatggcgt
    25441 tcaagtaagt acgatcgagc atgcgatggc tgctttatac gcttacgaga tcgataactg
    25501 cttgatcgag gtaaacgcac ccgaatttcc gatcctagac ggaagttctc gcttcttctc
    25561 cgaggaaatc caaaagacag gggtcgttga gcaaaacgct ccgaaggatt attatatcgt
    25621 aaagcacaag atcgaggtaa aagatgagga aaccggttct tcgttgatca tccttccgga
    25681 tgataagttc agcgtgaacg tattgatctc attcgattcg cccgtgcttt ccaaccaatt
    25741 cgccacgttg aacgatctca gcgaattccc gacagaattg gcggcttcac gtacgttcgt
    25801 attcgtacgc gaagtggaga tgttgctcaa ccacaacttg atcaagggtg gcgatttaga
    25861 caacgcgatc gttatctacg accagaagat accgcaagaa tctttggaca aattggcaga
    25921 tatgctgaac atccctcaca agaacgtgca ggaattaggc tatatcaata acaagccgct
    25981 tgtattcgat aacgaaccgg cacgtcataa attgatcgac gtgatcggag atatcgcctt
    26041 gatcggtaag ccgatccgcg gacgtgtgat cgctacccgt ccgggacata agatcaataa
    26101 ccagttagct cgtatgatcc gcaaggatat caagatgaac gaggtgcaag ccccggtata
    26161 cgatccgaac cgtgagccgg tgatggatat caaccgtatc cgtgaattat tgccgcaccg
    26221 ctatccgttc ttattggttg acaagattat cgaggttggc gggaactata tcgtaggcgt
    26281 aaagaacatc acgaccaacg aaccgttctt ccaagggcat ttccctcagg agccggtcat
    26341 gccgggagtc ctgcaggttg aggctatggc acaaacaggt ggtttgctag tcttgaattc
    26401 cgtagatgag ccagagcgtt attctaccta cttcatgaaa atagatggcg tgaaattccg
    26461 ccaaaaagtc gttccgggcg atacgttgat cttacgtctg gaattattgg caccgattcg
    26521 ccgcgggatc tctaccatga aagggtatgt attcgttggt gataaattgg ttagtgaagc
    26581 cgagttcatg gctcagattg taaaaaacaa ataataagat aaagtacgat aatgaatata
    26641 tctcctctag cagtcgttca tccagaggcc cagatcggcc agaatgtaac tatcgatccg
    26701 tttgccgtga ttgagaaaga tgtcgtaatc ggtgataatt gccgtatata ttctcacgcc
    26761 gttatcttgg atggcgcacg gattggtaaa aattgcaata ttttcccggg agcggtcgtt
    26821 gccggtatcc ctcaagacat gaaattcgcg ggggagacca cgacggcgga aatcggagat
    26881 aacacgacgc ttcgcgaatg cgtgacgatc aaccggggta ccgcttccaa aggtaagacc
    26941 gtggtaggtc gcgattgctt aatcatggct tattcgcacg tggcccatga ttgcgtctta
    27001 aaagaccata ttatcatcgg taacgcttcg caaatcgccg gggaggtaga gattgatgat
    27061 ttcgctatcg taagcggagg ttccttggtg catcagttca cgcgtatatc caagcacgtg
    27121 atggtacaag gcggttctcg tatcggaaaa gatatccctc cttatacctt gatcggccgt
    27181 gatccgatcg tttattgcgg tatcaatatc gtaggtttac gtcgccgggg attcacgaat
    27241 cagcaggtat tcttgattca agacatctat cgcacgctgt atacccgagg cttgaataat
    27301 acggaggcgc tgaaagcgat cgagaccgag tacgagccta gcgaggaacg ggatttgatc
    27361 ctcaatttca tcaagtcttc cagccggggt atcgtaagag gttcgatcga cgaataagcg
    27421 acacggacat ccggacatcc ggacaaccaa aaacaaatcg gcgcaaatct gcatcttacg
    27481 atgaggggtt tgcgccgatt cgctatttat gtcgccaaaa ggttatttat agggtgattc
    27541 ccgtgatctg ccggatcatt tcaagatcga tccccatggc tttcatcttc ttggcgtttt
    27601 ctaggttcgc ttctgcctcg ccttctgcca gtcctttcgc cttacctttc tccttatttt
    27661 ccgctctact ttccgctagt ccttccaggt atccttcaag cttcgccgaa tccaatacgc
    27721 cattttgtat catgaccgca ttcaagtgtt cgtcgtaagc gtatctatcc tcgggggtca
    27781 tggagtagta tctcaatttt tctcgagcct cgcctaatcc cggagtcatg gtgtcaggac
    27841 gaattgttcc tcttttaagg tagtccatcc attcctctag gggagtgacg gctatcttat
    27901 cgaacttatt gatccgtatg agtatatatt cggggaaaat ctcgggggat agcttggaga
    27961 caattacgct cctctctttc gtgttgacta ccaattgatc cttggtatgt acgccgatga
    28021 aatgattctg cccgtgataa aggtagtcct cgcccagtga tatgtactcg gttatggttt
    28081 tcgccacgcc atagagtacc tgttcgagat aatatagctt gcgaatattt tgtattttca
    28141 cgatgatgat ctcgcccttg tcgttaagcg ccttggcgta cacccggttg aacttgtcat
    28201 cctcatgaca gttgattacc ctcgctctcc agtagctcca cgatggtaat cttctctcca
    28261 agaaaaaccg tgagaaaacc ctccagcaca ccgaagttga ctttttgccg gagcagtctt
    28321 ttgatcgccc aatcgaaacg tatgtatcga tcttttaatt ctttcatgcg ttgctcctcc
    28381 tttttttatc catagttgat aggttttaag ttacggccca atagcgggcg gtgccgtaaa
    28441 gatatgtctt ttcgggcgaa atgcaaaaga ttgatatctg atactgtgat ttttattatt
    28501 tacccatatt acaattacct attcaaggtg acaactgccg ctaatatctc agccgcaggt
    28561 tccgtctctt tgacgaaggt tgaagacgaa gctacgacgg tcgcctcaga tacagggatc
    28621 agacgcgcac cctctttcat tatttatagc gacgtatatt gggtatatcc atatttttac
    28681 tacttttgag gcgataataa aactaaacga ctatgctatt tagatttc
//
LOCUS       DBMDTB010000044        28559 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_602_length_28559_cov_10.777637, whole genome shotgun sequence.
ACCESSION   DBMDTB010000044 DBMDTB010000000
VERSION     DBMDTB010000044.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 28559)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 28559)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28559
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_602_length_28559_cov_10.777637"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..774
                     /locus_tag="ACZPB4_08740"
     CDS             <1..774
                     /locus_tag="ACZPB4_08740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HIR1098338.1"
                     /translation="DRVILAGDHHQLPPTIKCIEAEREGLGRTLMQKIAHTKPETVSL
                     LKIQYRMHEDIMRFSSQWFYHNELESAPEVSGRGILRLDTPIVWFDTSECDFTENTRE
                     ETMSRVNRQEAELLVEQSRSYIQKISKERVLEENIDFGLISPYKAQVQYIRKLIKQDA
                     FFKPLRRLITVHTVDGFQGQERDVILISLVRANEDGKIGFLNDLRRMNVAITRARMKL
                     MILGDASTLTRHAFYNELYNYISQRGKIITINTKQEHEL"
     gene            764..1570
                     /locus_tag="ACZPB4_08745"
     CDS             764..1570
                     /locus_tag="ACZPB4_08745"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HIR1098339.1"
                     /translation="MNYKLLVLDLDGTLTNSKKEITPFTRETLLQAQEKGLHLVLASG
                     RPTYGIVPLAEELNMKQYGGFILSFNGGKVIDLMTDKVLFEQALPPDIVPVLYNRSKE
                     AGLAILSYNGKYILSEHPENKYVQYESFLTKMKIKATDDFLRDLHQPADKCLVVGEPE
                     MLVSLEEKLRQELGKRINVYRSEAFYLELVPKGIDKAASLSRLLERTRIKQEEVIAIG
                     DGFNDVSMIRFAGLGVAMANAQPPVKANADRITQYTNDEDGVARFIQELL"
     gene            1829..3061
                     /locus_tag="ACZPB4_08750"
     CDS             1829..3061
                     /locus_tag="ACZPB4_08750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008760410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HIR1098340.1"
                     /translation="MKYKLLVLDVDGTLLNDKKEITPRTHAALLKAQQMGVHVVLASG
                     RPTNGVQPLAEALELNHYGGFILSYNGGQIINAQTGELMFEKRIDPAMIPYLNRKAKE
                     NGFAIFTYHKDYILTDSPENKHVQEEAELNKMRIIGVENFPEAVDFAPCKCILTSDDE
                     NNLVGLENHWKKRLDGVLEAFRSEDYFLEVAPHFINKGNTLAVLMEMLNITTEEVVAI
                     GDGVADVSMLQLAGTGVAMGNARDSVKACADFTTLSNNMDGVAVAIEKAILATIKPTE
                     VPLDQLNARAKHALMGNLGIQYTYASEDRVEATMPVDERTRQPFGILHGGATLALAET
                     VAGLGSMILAKPDEMVVGMQVSGSHMSSAHEGDTVRAVGTIIHKGRSSHVWNVDIFTS
                     TDKLVSSVRVINSILKKK"
     gene            3058..4155
                     /locus_tag="ACZPB4_08755"
     CDS             3058..4155
                     /locus_tag="ACZPB4_08755"
                     /EC_number="5.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008909 - isochorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009234 - menaquinone biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismate synthase"
                     /protein_id="HIR1098341.1"
                     /translation="MIPRDSYEIIDTLIKQGRSFAIWRIPGEDRHHFRMQSAGSPCLL
                     YDIKDLNERSGFVIAPFQVTAERPIVLIQPDCFEIPSESDWDFSREKNEFPSNEIEIP
                     SESEEKERYAYHFSLFTSPLLKGSQDKLVLSRSKTIRKDPSFSPGKAFFAAVERYIRS
                     YVYLCHTPETGTWMGGTPEILLSGEKGDWQTVALAGTQSLRDGKLPKSWDHKNWREQQ
                     LVASYIRRQLSTLGITPEEKGPYSARAGEVSHLKSDFFFSLPNPEKLGDVLQLLHPTP
                     AVCGLPKEEAYHFIIENEGYDRSYYSGFIGWLDPKGKTDLYVNLRCMNILPQTFTLYA
                     GGGLLAASQLEDEWQETEDKLDTMRRIVGNL"
     gene            4170..5858
                     /gene="menD"
                     /locus_tag="ACZPB4_08760"
     CDS             4170..5858
                     /gene="menD"
                     /locus_tag="ACZPB4_08760"
                     /EC_number="2.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070204 -
                     2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-
                     carboxylic-acid synthase activity [Evidence IEA];
                     GO_process: GO:0009234 - menaquinone biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-succinyl-5-enolpyruvyl-6-hydroxy-3-
                     cyclohexene-1-carboxylic-acid synthase"
                     /protein_id="HIR1098342.1"
                     /translation="MYSDKKNILQLVALLIEHGVSNIVLCPGSRNSPIVHTLANHSFF
                     NCHSVTDERSAGFFAVGLALHGGKPAAVCCTSGTALLNIHPAVAEAFYQKVPLVVISA
                     DRPAAWIGQMDGQTLPQPGVFGSLVKKSVQLPEIHTDQDEWYCNRLINEALLELNHHG
                     KGPVHINVPISEPLFQFTTPELPKVRVITRYQGLNVYDRKYDDLIERLNKYSKRMMIA
                     GQMSLIYLFEKKICKLLYKHFTWLSEHIGNRIVPGLPIKNFDAILYATPEEEKEKLVP
                     ELVITYGGHIVSKRLKEFLRKHPPKEHWHVSLDGEVADLFGSLTTVIEMDAFEFLEKI
                     AYMLENRQIEYPKAWEYKSRNLPEPEFAYSEMAAIGGLIRSLPAESALHLGNSSTVRY
                     AQLYTVPETVEVCCNRGTSGIEGSLSTAIGYASASQKLNFIVIGDLSFFYDMNALWNG
                     NLHNNLRILLLNNGGGEIFQALPGFKMNERTHRYVTASHQTSAEGWATERGFSYSAVH
                     NAEELAAAMSAFTQTEQPSEHPLFMEVFTDKAEDVRLLKEYYHQLKNSSQAQNI"
     gene            5862..6686
                     /gene="menB"
                     /locus_tag="ACZPB4_08765"
     CDS             5862..6686
                     /gene="menB"
                     /locus_tag="ACZPB4_08765"
                     /EC_number="4.1.3.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008158132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008935 - 1,4-dihydroxy-2-naphthoyl-CoA
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009234 - menaquinone biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoyl-CoA synthase"
                     /protein_id="HIR1098343.1"
                     /translation="METKREWTTIKEYEEILFDFYNGIARITINRERYRNAFTPTTTT
                     EMSDAFYICRERPDINVVVLTGAGDTAFCAGGDMNVKGRGGYVGKDGVPRLNVLDVQK
                     QIRSLPKPVIAAVNGFAIGGGHVLHVVCDLTIASENAIFGQTGPRVGSFDAGFGSSYL
                     ARVIGQKKAREIWFLCRKYNAQEALDMGLVNKVVPLDKLEDEYVQWAEEMMLLSPLAL
                     RMIKAGLNAELDGQAGIQELAGDATMLYYMTDEAQEGGKAFLEKRRPRFEDYPKFP"
     gene            6724..7782
                     /locus_tag="ACZPB4_08770"
     CDS             6724..7782
                     /locus_tag="ACZPB4_08770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="o-succinylbenzoate synthase"
                     /protein_id="HIR1098344.1"
                     /translation="MVKERFYKTEVVPRCLTFKRPAGTSRGVYTTRKLWEVRIRKEDE
                     PSVIGIGECAPLPDLSCDYGVDYEITLSKACLDLEQKGYVDTESLRHYPSILFGLEIA
                     MRHYEQGGWRHYDTPFSRGQAGIPINGLIWMGDYKYMLEQVEEKMKEGFRCVKLKIGA
                     IDFDRELSLLKHIRTHFSAKEIELRVDANGAFTPPEAMDKLKRLAEMDLHSIEQPIRA
                     GQLEEMAHLAAESPLPIALDEELIGCNAPDEKRRLLETIHPQYIILKPSLHGGISGCT
                     EWIHLAEAILGSTPEQPKWWVTSALESQIGLNAIAQWCATLGNPLPQGLGTGEIFKDD
                     KHRLIQRKGDTIWFTNDL"
     gene            7786..8853
                     /locus_tag="ACZPB4_08775"
     CDS             7786..8853
                     /locus_tag="ACZPB4_08775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HIR1098345.1"
                     /translation="MPIQEDLQAFLAEWHDPSPFLEVQTSGSTGTPKRMRVRKDRMLN
                     SARLTCDYLGLKKGDKALLCMPLRYIAGKMMVVRSLYAGLDLEVREPSGHPLADWGDT
                     PLRFAAMIPLQVYNTLRVPEERKRLEQTDILIIGGGAIDAALEQEIRQMPNTVYSTYG
                     MTETLSHVALRRLNGPEASPYYHPFPSVTLSLSPDNTLVIDAPLVCDERLVTNDVARL
                     LPDGSFAIIGRKDNIINSGGIKIQIEEVEERLRPYLDLPYAITAAPDPRLGEAVVLLI
                     APRSCETVSPPRVTPHMKAIMSDSAQLSCEVSTVALASLPKYLRPRHVIEASEIPQTG
                     SGKIDRAACRELARNIITKTL"
     gene            8856..10814
                     /locus_tag="ACZPB4_08780"
     CDS             8856..10814
                     /locus_tag="ACZPB4_08780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3857 domain-containing protein"
                     /protein_id="HIR1098346.1"
                     /translation="MKRILTITAVSLLALSPMYGQDSCRYPQDPTLEKSQAYAGYDCV
                     TLLDSTAVTVQPTGSGAFAVCKAFKVQTPKGAVANRIIKYDYDPLTAHAEFRYATIYR
                     ANGDVINLDVTGACDYAAPARAIYWGARQIMLEVGRLQPGDVVEYEIAKKGFTYALLT
                     AGDDERFIPPMRGQFYDIVPFWATEPTVRKVYRVSMPMEKELQFQFYQGECTSSMRYE
                     DGRKVYTFASDDILPFAKEPNMVDLFDAAPKLMMSSTPRWEDKSVWFNKVNEDYGSFT
                     AIPEAQRKVDELIKGKKTEMEKIAVLTHWVADNIRYSGISMGKGEGFTLHNLKMNYTD
                     RCGVCKDIAGTLIAFLRMAGFEAYPAMTMAGSRVESIPADHFNHCVAVVKLASGTYMP
                     LDPTWVPFCRELWSSAEQQQNYLPGVPEGSDLCLTPVSAPENHYVRIHADNRLDEKGT
                     LRGQFTITAEGQSDSNIRRIFTTGWQSDWQNTMEKQLLAVSPNAKLLRVDYGKDPKNY
                     QAAPIKITFSYEIPDYAIIAGDQMLIKPLVMNNLYNQVKSFLRIDTKPENRAYGFKDA
                     CSRLVEQDETIRLPKGYTLLNAPKNDALRSNAADFEGSLSQEGDRNIVLRQKLALKKR
                     VYDAADWKGFRSAVNAYKSYGDYLIIKK"
     gene            10828..12411
                     /locus_tag="ACZPB4_08785"
     CDS             10828..12411
                     /locus_tag="ACZPB4_08785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3858 domain-containing protein"
                     /protein_id="HIR1098347.1"
                     /translation="MIKITYKLILLLSLLAMTVTSFAASEAEYGKVSKAWTLHADGSQ
                     EYRSSMELTLFTHTAMNSTYGESFIVYNPDFQTLKIHSSYTRQKDGTIVKTPDNAFVE
                     VLPRFAADAPAYNQLKEMVVVHTGLELGATIYLDYSIITKPGYYPALDINERLQETSP
                     VKECKVSISVPEGTPLACGLYGSPVKAVEESHDGIKEVHWTLRNIPASSREAFQPKNR
                     EASPHLVASTYPSGKAALATLDKRLKESQGYESKTFAQFLTDKSGNEQEKVNIIRDHI
                     LNNLSTCPIPMAMTGYTVRDIDTVLRSAYGTPLEIAQLLNVMLNAAGIPSEVLAVYPG
                     HLDTDACGLAAIQTLAVKATVDGKDQYLSASPLTNRGGLDKVVSLSGTSIEIETTPIQ
                     IKESRSVAISADQAKDGFAICVLPAISAGIDSWGMSALNSKRSNLFELPSLIREEVTY
                     TVTPAEGMKLQTSTQEQVISKPFGKVTRTITPRGNTIEVVRTIELNKQQFTPAEYSDV
                     RSLIHEWTNPDNRVLLFSL"
     gene            12513..15026
                     /locus_tag="ACZPB4_08790"
     CDS             12513..15026
                     /locus_tag="ACZPB4_08790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylglucosaminidase domain-containing
                     protein"
                     /protein_id="HIR1098348.1"
                     /translation="MKTLKYLLATMLLLGVCNLTHSQKLSLGIFPEPQEVTISSQTYA
                     PPHGYALRGINNPDADAVRLLKEALPFAKSGKSLPLEIKKLKDKAPEMQRSGAYTLTI
                     TKKGITIGIVDDNSLFYAAQTLKQLVKYDEGKKILPLCSIKDYPDVLFRGTVEGFYGQ
                     PWSHADRIEQIRFYGRIKLNTYIYGPKDDPYHSSPNWRKPYPAEEAEHIKELAKEASH
                     NKVNFVWAIHPGQDIQWNLTDSMNILSKFEKMYDLGVRSFAVFFDDISGEGARPEKQA
                     GLLNYIHKEFITKKNDVQPLIMCPTEYNRSWAKTDYLDILGTQLDPAIQIMWTGDRVV
                     ADITKEGVEWVNNRIRRPAYIWWNFPVSDYCQDHLLMGPAYGLDTQAAGTMTGFVSNP
                     MEYAEASKVAIFGVGMYTWNIENYDPTQAWKDACDFIMPEASMAFRIFCEHNCDPGPN
                     GHQYRREESANYVAPIQTFLAGYKKNTFPEQSANLLGTLFAQITASPSMIYSQSPNKR
                     LIEQINPWLIQFEFLGKAGTSALHMAHAWYEKDRSYTWQRYLETSALLDSMKLINRTL
                     NQKAQPKGVKVGSKVLHPFIVDLYRQTGRNLLSTDGIAPDEVKVSIPSIFTNIDQLKS
                     QPCAEGDNTVGYVPLFEVVKVQPNQYLGIGWEIQKEAESFCFNLPKSNQPGRVFEWSA
                     DGKSWSLIPHVSTENAKDTIRTIDPKARYIRMRNNSDQQMELYVLGFTATTKQDPQIN
                     EALMMYDMNLDTYKNLNPGEMIHIKCDDINAVSFFLSGSNENLVSITGLSQDGEKNIV
                     YQGNVGYIKLNKTMFEDFSSLEITTIGKESIHIHQIVRE"
     gene            15195..15833
                     /gene="nth"
                     /locus_tag="ACZPB4_08795"
     CDS             15195..15833
                     /gene="nth"
                     /locus_tag="ACZPB4_08795"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HIR1098349.1"
                     /translation="MRKEERYKGVLNWFKENVPVAETELHYDDPYQLLIAVILSAQCT
                     DKRVNMITPALFEAFPTPEVMAASTPEVVFEYIRSVSYPNNKAKHLVGMAKMLIEDFK
                     GVVPSDIDELQKLPGVGRKTANVIASVVYDKPAMAVDTHVFRVSNRIGLTNNSKTPLE
                     TEKELVKNIPEELIPIAHHWLILHGRYVCLARKPKCEECGLKPWCKHFLKQT"
     gene            15830..16711
                     /locus_tag="ACZPB4_08800"
     CDS             15830..16711
                     /locus_tag="ACZPB4_08800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098350.1"
                     /translation="MRISKKDITAFFVLFLGTIVCVRYFYKHMNDEQFVATVDPYSLV
                     VPSPTAIFAINRPPVFEKMILPMENIRKAFSDHTPAIFLSLIRQNLELSSFLIAYYPQ
                     GDVLYAPMDSHTAERIFKQLDVSFTFPAQQREETSVPVRYYPDVDKHFLGCYYHEGIF
                     VASYNRRLLVETVERQQTYPAHVIPELTDLIRKKGKRGAMNLFIKSAPLYLRVQMNDS
                     TEWRMKNQWLAMDLFYNEGSLCCFNEQPYEKALENFYPNLCDTITTRINRLFPQIKTT
                     TQVSHDEAVAYFTVCGN"
     gene            complement(16708..17814)
                     /locus_tag="ACZPB4_08805"
     CDS             complement(16708..17814)
                     /locus_tag="ACZPB4_08805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Wzz/FepE/Etk N-terminal domain-containing
                     protein"
                     /protein_id="HIR1098351.1"
                     /translation="MDTINEIKRQELPEEQEIDLIELAQKLWKERKFLLKGCGIAVVV
                     GLIVAFSIPKEYTTTVKLAPETQDAAKKSSLGGLAAMAGINLNAAAGADAISPDLYPD
                     VVQSTPFLLELFPVEVTDKEKELSTTLYDYMSEHQRKAWWGYIVSAPFKALGAVMSLI
                     SGDEEESEGLNPYHLTKDQEEVVKALQERVSVSVDKKTLVITASVQMQDPVISAQMTK
                     VVLENLQNYITNYRTQKVKQDLEFTQKVFGESRDAYYKAQRAYAAFEDANRNIISSSY
                     RTEQERLKNEMTLTFNVYNTLAQKLEQDKLRVQEETPVYTVIEPATVPLKASSPKKAL
                     ILVGFVFLALFGCIGYLFVKDMFVAAFKKEETGA"
     gene            complement(17821..20199)
                     /locus_tag="ACZPB4_08810"
     CDS             complement(17821..20199)
                     /locus_tag="ACZPB4_08810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010182969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLBB domain-containing protein"
                     /protein_id="HIR1098352.1"
                     /translation="MNLSFKNVLCVCCLLLSGSVYAQVPQDLIDKAKAAGMSDTQIQQ
                     ELAKRMKQEGGSVGSQATATDAKVSDRVMPVIDEGQSLEAQRRNNLPASAMENTVFGH
                     EIFSNKNLSFAPDLNIPTPKDYVLSAGDELLINVWGDSELNLKLKISPDGTILVPNLG
                     PVSVSGLTIAGAETRLRQELSQIMSTLSGSGEGNTFVSVSLSQIRSMKVNIVGEVVAP
                     GTYTLPSFATLFNALYAAGGVNKIGSLRSIKVYRNSKEIANLDVYDYLLNGKYTTNVR
                     LEENDMIMVGPYDQLAVVRGKVKRNRIFELRKGETLKQLLDMAGGFTGDAYTKDVQVK
                     RKSDSRYQISTVSEDKFASFVMQDGDSLQVDSVIPFYENRLVVTGAVWRPGEYELSPS
                     VRTVKQLVKQAAGLKGDEFAGRALITRLNPDFTTTMIAVDIRGILNGTAPDVELQAED
                     QLSIPSLFDLREPYTIKVGGAVNYPDTVLPYRHNLTIEDAIMMAGGLRESASSINVEV
                     ARRVKDPSSNQNVNRIADVYNFSLSEDFKLNAGDTIFTLEPFDEVYVRFSPGYHEQQV
                     VKVNGEITFAGSYVLATKNARLSDIIAKAGGVTPESYVKGASLKRQLTEDELKRMETL
                     LALSEANKQSRDSIGVALMNVKDYSVGIDLEKALANPGSIDDVVLRDGDELYIPQMQS
                     TVKMSGAVTYPNSVTYTKGMSVMDCLSQAGGYNDIARKYPIVIYMNGKVATTKRTAIF
                     FKRYPKVEPGCEIVVPTKTQRERRSLAEIMSISSSATSMAAMITSIVNMIKN"
     gene            complement(20318..21073)
                     /locus_tag="ACZPB4_08815"
     CDS             complement(20318..21073)
                     /locus_tag="ACZPB4_08815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HIR1098353.1"
                     /translation="MKIVFLGTGTSTGNPEIGCQCEVCTSKDPRDWRLRASILVETEG
                     KRVLIDCGPDFRWQMITNKIYHFDAVLVTHEHYDHVGGLDDLRPFGRYKDVDIYAEDN
                     VVEAIKTRIPYVFREHKYPGVPNLVLHTIGTKPFEAAGVMITPIRVMHAKLPILGFRI
                     GNMAYLTDLKYLPEEEYAKLENLDVLVIDALRKGEHQSHESLEEALANISRIQPKEAY
                     LIHMSHRIGLHAVVEKELPPHVHYSYDGLTVTF"
     gene            complement(21073..22086)
                     /gene="murB"
                     /locus_tag="ACZPB4_08820"
     CDS             complement(21073..22086)
                     /gene="murB"
                     /locus_tag="ACZPB4_08820"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HIR1098354.1"
                     /translation="MRIEQNYSLEKHNTFHLPVKTRWFMEYETEEELQRILHDEYFQE
                     CLSLHIGGGSNLLFINDYNGIIIHSRIKGISISAETDEYVSLRVGAAEIWDDVVAYAV
                     SKGWGGIENLSLIPGEAGAAAIQNIGAYGMEIKDVIESVEAYNQLTFEKRTFTNSDCE
                     YGYRNSYFKNEHHDPHIITYITLRLSKNPGFSVNYGNLKEELTKYPEVTLETIREAVI
                     TIRRQKLPDPEVLGNAGSFFMNPIITAEHFEKLKKQFPEIPSYPASEGKIKVPAGWLI
                     EQCGFKGKNHGSVGVYEKQALVLVNLGDARGDEIALVAESIRTAVKDRFGIELMPEVK
                     YVG"
     gene            22187..23023
                     /locus_tag="ACZPB4_08825"
     CDS             22187..23023
                     /locus_tag="ACZPB4_08825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098355.1"
                     /translation="MDENTSGISGEIQKMILDKLNTFNRGKTSDKGRYYILLPTSKTL
                     YYTLWFFTPSATYHPTVYLANLDLNAISSVNKAIKMVSNSFLPLFITTDIKDSPDNGD
                     DIISFGKYRGYHLHDIYTIDPRYVVWIADKYEPHVKSEMRFKELAVTYSKIYLDLQTR
                     KKYKMPVSRFVGTPGEKLSDLKLTITKVRIEDDSYKTQIIRGTEYFYVDQLLTAVDIA
                     GNYFLLRIKAKDRSLTTQTLPPGAHAFQVGEKLTLTSAKVLKHIESRTIKYTRIGYIK
                     IQ"
     gene            23206..23490
                     /locus_tag="ACZPB4_08830"
     CDS             23206..23490
                     /locus_tag="ACZPB4_08830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030527 - structural constituent of
                     chromatin [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HIR1098356.1"
                     /translation="MNKAELIEALADKTGLQKQEAKKVLDAYIEIVTERMSENEEIVL
                     VGFGTLIPRPQTQRLARNPKTGTPVMIPARTTVKFKPGKFLLEAMNAHLK"
     gene            23642..24295
                     /gene="upp"
                     /locus_tag="ACZPB4_08835"
     CDS             23642..24295
                     /gene="upp"
                     /locus_tag="ACZPB4_08835"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HIR1098357.1"
                     /translation="MRIVNLGDTNSILNKFVAELRDVDIQKDSLRFRRNVERIGEIMA
                     YEISKEFHYSTKDIQSPLGIAPMNTPDDQIVISTILRAGLPFHQGFLRYLDNAENAFV
                     SAYRKYKDRLNFDIHIEYIASPRLTGKTLIISDPMLATGSSMELAYEALLTKGVPGHV
                     HVASIISSKQALEYLQKKMPDDKTTIWIAALDNDLDDHSYIVPGLGDAGDLAFGEKE"
     gene            complement(24238..26136)
                     /locus_tag="ACZPB4_08840"
     CDS             complement(24238..26136)
                     /locus_tag="ACZPB4_08840"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing sensor histidine kinase"
                     /protein_id="HIR1098358.1"
                     /translation="MEDIQTQLDQCKLLLDRAEVGLWEADFVQRSYICSDYLMSIFGK
                     KGNNLSFFEFYYIIREDFRDLITTDFLSIQSVDTYEQIFPIITPTGEKWVRSRLCERK
                     LNNGVCVKALGILQILPNFKLKEEKISKMIDHNEMIFRKLYVNLPVGVELYDRDGYLI
                     DLNAKDMEIFGIRSKKDVLGVNIFSNPILPKDVIKKLKENKSVNFRLNYSFKKVDDYY
                     NTSKVGELDIVTKASILYDQRGEPSSYLLINLDNTEKMIAYNRISEFENVFTLVSVYA
                     KVGYALYDLYTFEGYAIKQWYENMGEKDGTPLSQIIGIYSYIHPNDAGYINSFFEEVK
                     QGKAHHFRREVRVKSGDGWKWICANITRNPQSVDPNKPEMICINYDITELKDSQLKRE
                     RAEELDRLKSAFLANMSHEIRTPLNAIVGFSQLLAETDDPEERHEFVEIIDSNNRMLL
                     QLISDILDLAKIESGTMDFKFADMSIKEVINEIVTSFRIKMPDNVALIAPKDSPECQI
                     YSDRMRLTQVISNFLNNAIKYTSEGCIILAYEIIGDEIKFSVTDTGDGMSQEIQAHIF
                     DRFYKGNTFKQGTGLGLSICETIVNRLGGRIGVNSELGKGSTFWFTHPYSFSPNAKSP
                     ASPNPGTI"
     gene            complement(26275..>28559)
                     /locus_tag="ACZPB4_08845"
     CDS             complement(26275..>28559)
                     /locus_tag="ACZPB4_08845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="3-keto-alpha-glucoside-1,2-lyase-like
                     domain-containing protein"
                     /protein_id="HIR1098359.1"
                     /translation="VQQAAVWALVKIGDKSVIPVLADLLKSNDKQVILLGQDALMAFN
                     GDIDQAVAKVIPSASDAGKIAGLELLAIRMADANLNTVLDQIKSGSSEVKKAAYTALK
                     DVVSEKDFTLLCGMLETAEASAVAPLQDAIIAAISKQPAATQVSNVNRRMIQAGDSKR
                     YLYYKVLSATGEKEALATIVEGLNKGNGAAKDAALDALLAWKGIEAADELFKVCQSAA
                     SDQVFDRALKRYVQLVSNPTFTRENRLLSLRKVMEIARTSEQKALILRQIQRADTFLA
                     LMYASEFLDSSDAAVRSAAVYAVWNIARNHPEYKGDNVKAILKRVLTMFDGEDARYDI
                     DALKQHLDAMPDEVGFVSIFNGKDLTGWKGLVENPIARAKMKPAQLAKAQEKADENMR
                     RDWKVENGLLVFDGTGYDNLCTEKQYGDFEMYVDWMLDPKGPEADAGIYLRGTPQVQI
                     WDTSRVNVGAQVGSGGLYNNQVNESKPSKVADNKLGEWNSFYIKMVGDRVTVVLNGEK
                     VVDNVILENYWDRKLPIFPVEQIEMQAHGSKVYYRNIYVKELEKQEPFKLSPEEEKEG
                     FKVLFDGTNMHEWTGNTVDYILEDGCISMVPSSSFGGNLYTKKEYGNFIYRFDFQLTP
                     GANNGVGIRTPMEGDAAYVGMEVQVLDCEHPIYQGNITPLQHHGSVYGIIPAREDHPK
                     AFKPVGEWNTEEIMADGDHIRVTVNGVVILDGNIRDAVKNGAPDGKEHPGLFNKKGHI
                     GFLGHGSPVKFRNIRIKELK"
BASE COUNT         7925 a         7279 c         6320 g         7035 t
ORIGIN      
        1 gaccgggtca tactagcggg cgatcatcac caattgcccc ctactattaa atgtatagaa
       61 gcggaacgag aaggcttagg acgtaccttg atgcaaaaga tagcccacac gaaaccggaa
      121 acggtctctc tcctgaagat ccaatatcgt atgcacgagg atatcatgcg cttctcctcc
      181 caatggttct atcataacga actcgaatcc gctcccgagg taagtgggcg gggaatcttg
      241 cgactggaca ctcccatcgt atggttcgat acgtccgagt gcgatttcac ggaaaatacg
      301 agagaggaga ccatgagccg tgtcaacagg caagaggcgg aattgctcgt ggaacaatca
      361 cgctcctata tacagaaaat atccaaggag agagtgttgg aggagaatat cgacttcgga
      421 ttgatctccc cttataaggc gcaggtacaa tacatccgta aattaatcaa acaggacgct
      481 ttcttcaagc ctttacgcag actgattacc gtacataccg tagacggttt ccaagggcaa
      541 gagcgcgatg tcatcttgat cagtttggtg agggccaacg aggatggaaa gatcggtttc
      601 ttgaacgact tacggcgcat gaacgtagcg atcacccgtg cccgtatgaa actgatgatc
      661 ttgggagacg cttccaccct tacccggcac gcattttata acgaactcta taattatatc
      721 tcccaaagag gtaaaataat cacgatcaac acgaaacaag agcatgaact ataaattatt
      781 ggtactggat ttagacggta cactgacaaa cagtaaaaaa gagatcaccc cgtttacgag
      841 ggaaaccctt ctgcaagcgc aggaaaaagg attgcatcta gtcttagcct ccggccggcc
      901 cacctacggt atcgtgcctt tagccgagga actgaacatg aagcaatatg gtggttttat
      961 cctttccttc aacggcggta aggtgatcga cttgatgaca gacaaagtac ttttcgaaca
     1021 ggctttgcca cccgatatcg tacctgtttt atacaaccgc tccaaagaag cgggactggc
     1081 tatcctttcc tacaacggta aatatatctt aagcgagcat ccggaaaata aatacgtaca
     1141 atacgaatct ttcttaacca aaatgaagat caaggctacc gacgattttc tgcgggattt
     1201 gcatcagcca gccgataaat gcttggtggt aggcgaaccg gagatgttgg tatcgttgga
     1261 agagaagctc cgccaagaat tagggaaacg tatcaacgta tatcgttccg aggcattcta
     1321 tctggagctt gtccccaaag gtatcgacaa agccgcctcg ttatcccgct tactagagcg
     1381 aacccggata aaacaggagg aagtgatcgc tatcggcgac ggtttcaacg atgtatccat
     1441 gatccgtttc gccggattgg gagtcgctat ggccaacgcc cagccccctg tcaaggccaa
     1501 tgccgaccgc atcacccaat acacgaacga tgaggatgga gtggctcgtt tcatccaaga
     1561 attgctttga aaaaaacacg tacgtatttt ccgagaaaca cgtacatgtt ttcgcaagaa
     1621 cacgtacgtg ttttttcaga gacatttaca ccagtatcga cacaggccaa tgcctatatc
     1681 ggcataagcc tgtacgtata tcgccgcaag gctacaccga tataggcgtg agcttgcgcc
     1741 gatatacgta aattcctttc atggaaatgt cttctaacta tcaactattt tatgtacatt
     1801 tgtattctaa accataaaat aagacgccat gaagtacaaa ttattagtct tagacgtaga
     1861 tgggacgttg cttaacgaca agaaagagat aactccccgg acccatgccg ccctgttaaa
     1921 ggctcagcag atgggagttc atgttgtatt ggcatccggc cgacccacca acggggttca
     1981 acccttggcg gaggctcttg aattgaatca ttacggtggt ttcatattat cttataacgg
     2041 aggtcagatc atcaatgccc agaccggaga attgatgttc gagaaacgaa tcgatccggc
     2101 catgattcct tatttgaacc ggaaggcgaa ggaaaacggt tttgctatct tcacgtatca
     2161 caaggactat atcctgaccg atagcccgga aaacaagcat gtccaagagg aggccgaact
     2221 caataagatg cgcatcatcg gtgtggagaa tttcccggaa gcggtggatt tcgcaccctg
     2281 taagtgtatt cttaccagcg atgacgagaa caatctagtg ggtctcgaaa atcattggaa
     2341 gaaacgtctg gacggggtat tggaagcttt ccgctccgag gactatttct tggaggtagc
     2401 tcctcatttc atcaataagg gaaatacgtt ggcggtattg atggagatgc tgaatatcac
     2461 gaccgaagag gttgtcgcta ttggtgatgg cgtagccgac gtatccatgc ttcaattagc
     2521 cggtaccggc gtggcgatgg gtaacgcacg cgactccgta aaggcttgcg ccgatttcac
     2581 gaccttatct aataatatgg atggtgtggc ggtagcgatc gagaaagcga tccttgccac
     2641 gatcaaaccc acggaggttc cgttagatca actaaacgca cgggccaaac atgccttaat
     2701 gggtaatcta ggcattcaat atacctatgc gtcggaggat cgtgtggaag cgaccatgcc
     2761 tgtagacgaa cggacccgcc agcctttcgg tatcttgcac ggaggcgcta cgctggcttt
     2821 ggcggagacc gtggccggac taggttccat gattctggcg aaaccggacg agatggtagt
     2881 cggcatgcaa gttagcggca gccatatgtc gtccgcccac gagggagaca cggtacgtgc
     2941 cgtcgggacg attatccaca aaggccgttc atcccatgtg tggaacgtag acatattcac
     3001 ctctaccgac aaactggttt cctcggtacg ggtaatcaat agcatactaa agaagaaatg
     3061 attccaagag attcttacga aataatagac acgttgatca agcaaggccg gagtttcgct
     3121 atttggcgta ttcccggtga ggataggcac catttcagga tgcaaagcgc cggctctcct
     3181 tgcctattat acgacataaa agacttaaat gaacggagcg gttttgtaat cgctccgttt
     3241 caggtgacag cggaacgacc tatcgtttta atccaaccgg attgctttga aatcccctcc
     3301 gaatccgatt gggatttctc tcgagagaaa aacgaattcc cttcgaatga aatcgaaatc
     3361 ccatccgaat ccgaggagaa ggaacgatac gcttaccatt tctccctgtt taccagccct
     3421 ttgctaaaag gaagccaaga taaactagtc ctatcccgta gcaaaacgat ccggaaagat
     3481 ccctctttct cacccggcaa ggcattcttc gccgcagtag aacgatatat ccgctcctat
     3541 gtctaccttt gccatacccc ggaaaccgga acttggatgg gtgggacacc ggaaatcttg
     3601 ttatccggcg agaaaggcga ctggcaaacg gtagctttgg ccggaaccca atccttacga
     3661 gacgggaaat taccgaaaag ctgggaccat aagaattgga gagaacagca attagtcgcc
     3721 tcctatatac gccgccagct gtccaccttg ggtattactc ccgaggagaa ggggccttat
     3781 tcagcccggg ccggagaggt ttcccatttg aaaagcgatt tcttcttctc cttgccgaat
     3841 cccgagaagc tgggtgatgt ccttcaacta ttacacccta ctccagccgt ttgcggtctt
     3901 cccaaggagg aggcttatca tttcatcatc gagaatgagg ggtacgatcg tagctattac
     3961 tccggtttca tcggttggct ggatcccaaa ggcaaaacag atctgtacgt aaacctccgt
     4021 tgcatgaata tcctccccca aacctttacg ctgtatgccg gaggcggtct gttggcggcc
     4081 tcgcagctag aggatgagtg gcaggagaca gaggataaat tagatacgat gcggagaata
     4141 gtgggtaatt tataatttta tatcatataa tgtatagcga taaaaagaac atccttcaat
     4201 tggtagcctt gctgatagag cacggcgtaa gtaatatcgt gctatgtccg gggagccgga
     4261 actctccgat tgtgcacaca ttggcaaacc attcgttctt caattgccat tccgtgacgg
     4321 atgagcgaag cgcgggattc tttgccgtag ggctagcgtt gcacggaggt aagccggcgg
     4381 ctgtttgctg tacctcgggc acggccttgc tgaatataca tccggcggta gcggaggctt
     4441 tctatcagaa agttccgctt gtcgtgatat ccgccgaccg ccccgccgca tggatcgggc
     4501 aaatggacgg acagaccttg ccgcaacccg gggtgttcgg ctcgctggtg aagaaatcgg
     4561 tacagctacc ggaaatacat acggatcaag atgaatggta ttgtaatcga ttgatcaacg
     4621 aggctttgtt ggaactgaac catcacggca aagggccggt tcatatcaac gtcccgatct
     4681 ccgagccttt atttcagttc acgacacccg aattgccgaa ggtacgggta atcacccgtt
     4741 atcaaggcct aaacgtgtac gaccggaaat atgacgatct gatcgagcgt ttgaacaaat
     4801 atagcaagcg aatgatgata gcgggacaaa tgagcttgat ctatctcttc gagaagaaaa
     4861 tatgcaagtt actatacaag catttcactt ggctctccga gcacatcggc aaccgtatcg
     4921 taccgggatt gccgatcaag aatttcgacg ccatcctgta cgctacccca gaggaggaaa
     4981 aagagaagct ggttcccgag ctcgtgatca cctacggcgg ccatattgtc tccaagcggc
     5041 tgaaagagtt tttgcggaaa cacccgccta aggagcattg gcatgtctca ttggatgggg
     5101 aggtagcgga tttattcggt agcctgacca cggtgatcga gatggacgct ttcgagtttc
     5161 tggagaaaat cgcttatatg ctggagaata ggcagattga atatccgaag gcttgggaat
     5221 ataaatcccg gaatctgccg gagccggagt tcgcttactc cgaaatggcg gcgatcggtg
     5281 gtttgatacg ttcgcttccg gctgaatctg ccttgcatct ggggaatagc tccaccgtac
     5341 gttacgcgca attgtacacc gtacccgaga cggttgaggt ttgttgtaac cgaggtacga
     5401 gcgggatcga aggctctttg tctacggcca tcggatacgc ctcggcctcg caaaaactaa
     5461 actttatcgt tataggcgat cttagtttct tctatgatat gaacgcattg tggaacggaa
     5521 acttgcacaa taaccttcgc atcctgctct tgaacaacgg aggtggcgag atcttccaag
     5581 ccttgccggg attcaagatg aacgagcgta cgcaccgtta cgtcaccgcc tcccaccaga
     5641 cctcagcgga gggatgggcc acggaaaggg gattctccta ctccgccgtt cataacgccg
     5701 aggagttggc agctgcgatg agcgccttta cccaaacgga gcaaccgagc gaacatcccc
     5761 tattcatgga ggttttcacg gacaaagcgg aagacgtacg attgctcaag gaatattatc
     5821 atcaactaaa aaattcatcc caagcacaaa acatataata tatggaaacg aaaagagaat
     5881 ggacaaccat caaggaatac gaggagatct tatttgattt ctacaacggc atcgcccgca
     5941 ttacgataaa ccgggaacgg tatcgcaacg cttttacccc gactacgacc acggagatga
     6001 gcgacgcctt ttacatctgc cgggaacgtc cggacattaa cgtagtcgtt ctgacaggag
     6061 ccggagatac ggcgttttgc gcgggaggcg atatgaacgt gaaaggacgt ggcggctacg
     6121 tgggtaaaga cggcgtacct cgcttgaacg tattggacgt acaaaagcag atccgctctc
     6181 tcccgaaacc cgtcatcgca gccgtgaacg gtttcgctat cggcggcgga cacgtattgc
     6241 acgtggtttg tgaccttacg atcgcttccg agaacgctat cttcggacag acaggccctc
     6301 gtgtgggtag cttcgacgcc gggttcggct cttcttacct cgcccgtgtg atcggacaaa
     6361 aaaaggcccg tgagatctgg ttcctatgcc gcaagtacaa tgcacaggag gctttggata
     6421 tgggtctggt aaataaggta gtccccttgg ataaattaga ggacgagtac gttcaatggg
     6481 ccgaggagat gatgttgctt agcccgttgg ccttgcgcat gatcaaggcg ggcttgaacg
     6541 ccgagttgga cggacaggcc ggtatacaag agttggccgg agacgctacc atgctttact
     6601 atatgacgga cgaggcgcag gaaggcggca aggcattctt ggagaaacgc cgtccacgct
     6661 tcgaggacta cccgaagttc ccgtaaaggg aattgagaat tgagaattga aaattgagaa
     6721 tgaatggtga aggagaggtt ttataaaaca gaggtggttc cccggtgctt gactttcaag
     6781 cgaccggcag gaacctcacg gggtgtttac acgacccgga aattgtggga ggtccgaatc
     6841 cgcaaggaag acgaaccctc ggttattggt atcggagaat gtgcccccct gccggatctc
     6901 agttgcgatt atggagtgga ttacgagatc acgttatcca aggcttgcct cgatctggaa
     6961 cagaagggat atgttgacac cgaatctttg cgccattacc catccatcct tttcggattg
     7021 gaaatcgcca tgcgtcatta tgaacagggt ggttggcggc attacgacac gcccttctcg
     7081 cgggggcaag cgggcatccc cattaacgga ctgatctgga tgggcgatta taagtacatg
     7141 ctggaacagg tagaggaaaa gatgaaggag ggcttccgct gcgtcaagct gaagatcggc
     7201 gctatcgatt tcgaccggga actctcttta ttgaaacata tccgcacgca tttctccgcc
     7261 aaggaaatag agcttcgggt agatgccaac ggcgctttca ctcccccgga ggcgatggat
     7321 aaactgaagc ggctcgccga gatggactta cattccatcg agcagcctat ccgtgccggg
     7381 cagttggaag aaatggcaca ccttgcggca gagtcacccc ttcccatcgc tctcgacgag
     7441 gaactgatcg gctgtaacgc cccggacgag aaacggcggt tgttggaaac tatccatccc
     7501 caatacatta tattaaagcc ttccctccac ggaggtatct ccggatgtac ggaatggatt
     7561 cacttagcgg aagctatctt agggagtacc cctgaacaac ctaaatggtg ggtcacctcc
     7621 gctctggaat cgcaaatcgg actgaacgct atcgcccaat ggtgcgccac gttaggtaac
     7681 ccgctaccgc aaggtctggg aaccggcgag attttcaagg atgataaaca tcggttgatc
     7741 caacgaaaag gagacaccat ctggttcacc aacgaccttt gacctatgcc gatacaagaa
     7801 gatttacagg cattcttagc tgaatggcac gatccctccc cttttctgga agtccagacc
     7861 tccggctcca ccggtacgcc caagcggatg agagtgcgca aggaccggat gctgaacagc
     7921 gcccggctta cctgcgatta tctgggtctt aagaagggcg acaaggccct gttatgtatg
     7981 cccctgcgct atatagccgg aaagatgatg gtggtccgct ccctatacgc cggactggat
     8041 ctggaggtgc gtgaaccctc cggacacccg ttggcggatt ggggggatac gcccctgcgc
     8101 tttgccgcca tgatcccctt gcaggtttac aatacgttgc gagtacccga ggaacgtaaa
     8161 cggctggagc aaacggatat cctgattatc ggcggcgggg cgatcgacgc ggccttggaa
     8221 caggagatac ggcagatgcc aaacacggtt tattccacct acggaatgac ggagacgctg
     8281 tctcacgtcg ccctgcgccg gctgaacggg ccggaagcct cgccctatta ccatcccttc
     8341 ccctcggtga cgttatcctt gtcgccggac aataccttgg tgatagacgc cccattggtt
     8401 tgcgacgagc ggctggtgac gaacgatgtc gcccgcctgc tgccggacgg gagtttcgcc
     8461 attatcggaa ggaaagataa tatcatcaat agcggaggta tcaagataca gatcgaggag
     8521 gtggaagagc ggctacggcc ctacctagac ctcccctatg ccatcaccgc cgcccccgac
     8581 cctcggttgg gagaggcggt agtcttacta atcgccccaa ggtcatgtga aacggtatca
     8641 ccccctcggg tgacaccaca catgaaagct atcatgagcg actccgcgca gctatcatgt
     8701 gaggtatcga cagtggctct cgccagcctg cccaagtacc tccgtccaag gcacgtcata
     8761 gaggcaagcg agatccccca aaccggaagc ggcaagatcg atcgtgccgc ctgccgggag
     8821 ctagcgagaa atatcatcac aaaaacacta taaacatgaa aaggattcta acaatcaccg
     8881 cggtctccct attggcctta tcgcctatgt acgggcagga ttcttgccga tacccgcaag
     8941 atcctacctt ggagaaatcg caagcctacg caggatacga ctgcgtcacc ttgctggaca
     9001 gcaccgccgt cacggtacaa cctaccggct cgggggcttt cgccgtatgc aaggctttta
     9061 aggtacagac tcccaaggga gccgtcgcca accgtatcat caaatacgat tacgacccgc
     9121 tgacggcgca tgccgagttt cgttacgcca cgatctaccg tgcgaatggc gacgtgatca
     9181 atctcgacgt gactggggct tgcgactatg ccgcccccgc acgtgccatc tactggggcg
     9241 cccggcagat catgctggaa gtgggccgcc tgcaaccggg agatgtcgtg gagtacgaga
     9301 tcgccaagaa aggtttcacc tacgccttgc tgacggcggg cgacgacgag cgtttcatcc
     9361 ctcctatgcg gggacagttt tacgatatcg tccccttctg ggctaccgag cctaccgtgc
     9421 gtaaggtata ccgggtatcc atgccgatgg agaaagagtt gcaattccag ttctaccaag
     9481 gcgaatgtac ctcttccatg cgatatgagg atggacggaa agtatatacc ttcgcctccg
     9541 acgatatcct tcctttcgcc aaggaaccga atatggtaga cctattcgac gctgccccga
     9601 agctcatgat gtccagcacg ccccgctggg aagataaatc cgtatggttc aataaggtta
     9661 acgaggatta cggaagcttt accgcgatcc cggaagccca aaggaaggta gacgagctga
     9721 tcaaaggcaa gaagacggaa atggagaaga tagccgtatt gacccactgg gtagccgata
     9781 acatccgtta ctccggaatc tcgatgggta aaggcgaggg tttcacgctt cacaacctaa
     9841 agatgaatta taccgatcgt tgcggtgtct gcaaggatat cgccggtacg ttgatcgcct
     9901 tcctccgcat ggccggattc gaggcttacc cggcgatgac catggcggga agccgtgtag
     9961 aaagcatccc cgccgaccat ttcaaccatt gcgtggcggt ggtaaaactg gctagcggca
    10021 cgtatatgcc tctcgacccg acttgggttc ctttctgccg agaattatgg agtagcgccg
    10081 agcaacagca gaactacctc ccgggtgtgc ccgaaggctc cgacctctgc ctgacccctg
    10141 tctccgcccc agaaaaccac tacgtccgca tccacgctga caaccgccta gacgagaaag
    10201 gcacgctccg cggacaattc acgatcaccg ccgagggaca gtccgacagc aatatccgcc
    10261 gcatcttcac caccggatgg caatccgact ggcagaacac gatggagaag caattgctgg
    10321 ccgtatcccc caacgccaaa ctgcttcgtg tagattacgg taaggacccg aagaactatc
    10381 aagcggcccc tatcaagatc acgttctctt atgagatccc cgattatgcg atcatcgccg
    10441 gagaccagat gcttatcaag ccgctagtca tgaataacct ctacaatcaa gtgaagagtt
    10501 tcttgcgtat cgatacgaaa ccggaaaacc gtgcgtatgg attcaaggac gcttgctccc
    10561 gtttggtaga acaagatgag accatccgtc tccccaaagg ctataccctc ctgaacgccc
    10621 cgaagaatga cgccctgcga agcaatgcgg ccgatttcga aggttccctt tcacaggaag
    10681 gcgaccggaa catcgtcttg cgccagaagc tagcgttgaa gaagcgtgtc tacgacgcag
    10741 ccgactggaa aggcttccgt tccgccgtga acgcctataa gagttatggt gactatttga
    10801 ttatcaagaa ataaaaaaag aaagacaatg attaagataa cctataaact gattcttctc
    10861 ctaagcttgt tagcgatgac ggttacttca ttcgccgcat cggaggctga gtacgggaaa
    10921 gtatcgaaag cttggacctt gcatgccgac ggcagccaag aatatcgatc ctccatggag
    10981 ttgacgctct tcacgcatac cgcaatgaat agcacgtatg gcgagagttt tatcgtctac
    11041 aatcccgatt tccaaacact gaagattcac tcatcctata cgaggcagaa agacggtacg
    11101 atcgtaaaga cacccgataa cgccttcgtg gaggtcctgc cccgtttcgc cgccgacgct
    11161 ccggcctata accaactcaa ggaaatggtc gtggtacaca ctggcctaga acttggggcc
    11221 acgatttact tggattactc tattatcaca aaaccgggct actatccggc tctggatatc
    11281 aacgagcgac tacaagagac ctctcccgtg aaggaatgca aggtctctat ttccgtaccg
    11341 gaagggaccc ccttggcttg cggtctatac ggctcccccg taaaagccgt ggaagagagc
    11401 catgacggta taaaggaggt acactggaca ctacggaaca ttcccgcttc ctcccgtgag
    11461 gctttccaac caaagaaccg tgaggcttca ccccacttgg tagcctctac ctatccttca
    11521 ggtaaagcgg ccttagccac tttggataag cgcttaaagg aatcgcaggg atacgagagc
    11581 aaaaccttcg cccaattcct caccgataaa agcggtaacg aacaagagaa ggtgaacatc
    11641 atccgagacc atatactcaa caatctcagt acctgtccta tccccatggc gatgaccggc
    11701 tataccgtcc gtgacatcga taccgttctc cgcagtgctt acggtacgcc gctagagatc
    11761 gcacagctct tgaacgtgat gttgaatgcc gccggaatcc cgtcggaagt cctcgccgtc
    11821 tatcccggcc atctcgatac ggacgcttgc gggctggctg ccatccagac actagccgta
    11881 aaagccactg tcgatgggaa agatcaatac ctatccgcct ccccgctgac aaatcgtggc
    11941 ggactagata aggtagtctc cctctccgga acttccattg agattgagac cacacctatt
    12001 cagattaagg aaagtagatc cgtggccatc tccgccgatc aagcaaaaga cggtttcgcc
    12061 atctgcgtat tgccagccat ctccgccgga atcgatagct ggggcatgag tgccttgaac
    12121 agcaagcgtt ccaacttatt cgaactcccc tccctaatca gggaagaggt aacatacacg
    12181 gttactcccg ccgagggcat gaagttgcag acctccacgc aagagcaagt gataagcaag
    12241 ccttttggta aagtaacccg cacgatcaca ccaagaggaa atacgatcga ggtggtacgt
    12301 acgatagagt tgaacaagca acagttcact cccgccgaat atagcgacgt gcgtagcttg
    12361 atccatgaat ggacaaatcc ggataaccgg gtattgctat tctccctata agatctaaat
    12421 acggagggca cggaacaaat ctgtgtattc cgtgtgctcc gtgtttaatt atttcataca
    12481 tttacgaacg ttaacattaa atcatatcgc atatgaaaac actaaagtat ttactcgcca
    12541 ccatgctcct tctaggcgtt tgtaacctaa cgcatagcca aaagctatct ctaggaatct
    12601 tccccgagcc ccaagaggta actatctcca gccagacata cgcgccgccc catggatacg
    12661 ccctacgagg cataaataat ccggacgcag acgcagtcag actacttaaa gaagcgctac
    12721 ctttcgctaa atccggcaaa tccctcccct tagagatcaa gaagctaaaa gacaaagccc
    12781 cggagatgca acgctcgggt gcctatacgc tgacgatcac taaaaaaggt atcacgatcg
    12841 ggatcgtaga cgataattcc ttgttctacg ccgcccaaac cctcaagcaa ttggtcaagt
    12901 atgacgaggg taagaagatc ctgcctctct gctcgatcaa ggactatccg gacgtattat
    12961 tccggggtac cgtggaagga ttctacggac agccttggag ccacgccgac cgtatcgagc
    13021 aaatccgctt ttacggaagg atcaagctga acacctatat ctatggtccg aaagatgatc
    13081 cttatcacag ttcccccaac tggcgcaaac cttatcccgc cgaggaagcc gagcatatca
    13141 aggaactagc gaaagaggcc tcccataaca aggtgaactt cgtttgggcc atccacccgg
    13201 gacaagacat tcaatggaac ctaacagata gcatgaatat cctttccaaa ttcgagaaaa
    13261 tgtacgattt gggcgtacgc tctttcgccg ttttcttcga tgatatatcc ggagagggag
    13321 cccgcccgga aaagcaagcc ggcttattga attacatcca taaggagttt attaccaaga
    13381 aaaatgacgt gcagcccctg atcatgtgcc ctaccgaata caaccgctca tgggctaaga
    13441 ccgattatct ggatatcctc ggtacccaac tcgaccccgc tatccaaatc atgtggaccg
    13501 gagaccgtgt cgtagccgat atcacgaaag aaggcgtcga gtgggtaaac aaccgtatcc
    13561 gtcgtcccgc ctatatctgg tggaacttcc ccgtaagcga ttattgccaa gatcatttgt
    13621 tgatgggacc cgcgtacggc ctagatacgc aagccgccgg caccatgacc ggattcgtat
    13681 ccaatcctat ggaatacgct gaggcttcca aggtcgctat attcggcgtt ggaatgtaca
    13741 cttggaatat cgagaattac gatcctacac aggcatggaa agacgcttgc gacttcatca
    13801 tgccggaggc ctccatggct ttccgcattt tctgcgagca taactgcgat ccgggtccga
    13861 acggacatca ataccgccgg gaagagtccg ctaactatgt ggctcctatc cagacattcc
    13921 tcgccggata taagaaaaac acgttcccgg agcaaagcgc gaatcttctg ggaaccttat
    13981 tcgctcaaat cacggcttcc ccgagtatga tctatagcca aagtcccaat aaacgcttga
    14041 tcgagcaaat caatccatgg cttatccaat tcgagttctt aggaaaagcc ggaacaagcg
    14101 ctctgcatat ggcgcacgct tggtatgaga aagaccggtc ttatacgtgg caacgctatc
    14161 tggaaacatc cgctttgcta gatagcatga aactgataaa ccgcacgctg aaccagaagg
    14221 cgcagcctaa aggcgtgaaa gtcggatcga aagtcttaca ccctttcatc gtagacttat
    14281 accgccagac aggtcgtaac ctgctatcta cggacggtat cgccccggac gaggtgaagg
    14341 ttagcatccc ttccatattc acgaatatcg accaattaaa gagccagcct tgtgccgagg
    14401 gtgacaatac ggtcggttac gttcccctat tcgaggtagt caaggtacaa cctaaccaat
    14461 atctgggtat cggctgggaa atccagaaag aagcggaatc cttctgtttc aatcttccga
    14521 aaagcaacca acccggacgg gtattcgagt ggtccgccga cggaaagagc tggagcctaa
    14581 tccctcatgt ctccacggaa aacgctaaag atacgatccg caccatcgac ccgaaagccc
    14641 gttatatccg tatgcgaaat aactcggatc agcaaatgga gctatacgta ctaggattca
    14701 cggcgacaac caaacaagac ccgcaaatca atgaggctct tatgatgtac gatatgaacc
    14761 tagatacgta taagaacttg aacccgggag aaatgattca tataaaatgt gatgatatca
    14821 acgccgtatc tttcttcctc tccggaagta acgagaatct ggtatccatc accggcctct
    14881 cccaagatgg cgagaaaaac atcgtctatc aaggaaacgt aggctacatc aaattaaata
    14941 aaaccatgtt cgaggatttc tcttctttag aaatcaccac aataggaaaa gaatctatac
    15001 atatccacca gatcgttagg gaataataaa taaaaaagta ccgatttctt tctctcttag
    15061 atggaagaag gagatcggta cttttttatt tattcgtaca attcgggtgt atcttatttt
    15121 tggcacatct ccgcttgtat attcctatta aaagttatac ctttaggatg cgaaaaacag
    15181 aaaccgaaaa agcaatgcga aaagaagaaa ggtataaagg cgtattaaac tggtttaagg
    15241 aaaacgtacc ggtagccgag actgaactac attatgacga cccctatcaa ctattgatag
    15301 cggtaatcct atccgcacaa tgcacggata agcgagtgaa tatgatcaca cctgccctgt
    15361 tcgaggcttt cccgactcct gaggtaatgg cggctagcac accggaagtt gtctttgaat
    15421 acatacgaag cgtatcttac ccgaacaata aggctaaaca tctggtaggt atggcgaaaa
    15481 tgctgataga ggatttcaaa ggcgtggttc cctccgatat tgatgagcta caaaaactgc
    15541 cgggcgtagg aagaaaaaca gcgaacgtaa tcgcatccgt agtatatgac aagccggcca
    15601 tggcggtgga tacgcacgta ttccgtgtct ccaaccggat cggcttgacc aataatagca
    15661 agacaccttt ggaaacggaa aaggagttgg tgaagaacat tccggaagaa ttgatcccca
    15721 tcgcccatca ctggttgata ttgcatggaa gatatgtttg cctcgcccgg aaaccgaaat
    15781 gtgaggaatg cggattaaag ccttggtgta aacacttcct aaagcaaaca tgaggatcag
    15841 caagaaagac ataacggcat tttttgtctt gtttctgggt acgatcgtat gcgtgaggta
    15901 cttttacaag catatgaacg acgagcaatt tgtcgctacg gtagatccct atagtttggt
    15961 cgttccaagc cccacggcaa tttttgccat caatcgtcct cctgtattcg agaagatgat
    16021 actacccatg gagaatatac gcaaggcgtt ctcagatcat acccccgcta ttttcctttc
    16081 tttaatacgg caaaatctgg aattatcgtc tttcctaatc gcttattatc cacaagggga
    16141 tgtcttgtac gcccctatgg atagtcatac ggcagagcgt attttcaagc aactggacgt
    16201 ctctttcact tttccggccc agcaacgaga ggaaacctcc gttcctgtta gatattatcc
    16261 tgatgttgat aagcattttc taggttgtta ctaccacgag ggtatattcg tagcgtccta
    16321 caaccgaaga ttattggtag agacggtgga aaggcaacag acataccccg cacatgtcat
    16381 tccggaacta acagatctga ttcgtaaaaa aggcaagcgt ggcgcaatga atctcttcat
    16441 caaaagcgcc cctttatatt tacgggtaca aatgaatgac tcgacggagt ggagaatgaa
    16501 aaatcaatgg ttggcaatgg atttattcta taatgaagga agcctttgct gcttcaacga
    16561 gcaaccctat gagaaagcct tggagaactt ttaccccaat ttatgcgata cgataaccac
    16621 ccggatcaat cggctattcc cgcaaataaa aaccacgaca caagtcagtc atgacgaggc
    16681 cgtggcatat tttacggttt gcgggaatta agctccagtc tcttctttct tgaaagctgc
    16741 cacaaacata tcttttacga ataaatatcc gatacatccg aataaagcga ggaagacaaa
    16801 accgaccaag ataagtgcct tcttaggaga agatgctttc aaaggtacgg tagccggctc
    16861 gattacggta tacaccggag tttcttcctg tacacgcaat ttatcttgct ccaacttctg
    16921 cgccaacgta ttgtaaacat taaacgtaag ggtcatctca ttcttcaaac gttcctgctc
    16981 cgtacggtag ctggaagaga taatattacg gttggcatcc tcgaaagcag cgtacgcacg
    17041 ttgcgcttta taataagcgt cacgtgactc gccaaatacc ttctgggtaa attccaaatc
    17101 ttgctttact ttctgcgtac gataattcgt aatataattc tggaggtttt ccaaaacgac
    17161 ctttgtcatc tgagcggaaa taaccgggtc ctgcatctgt acggaagccg tgataaccaa
    17221 ggtcttcttg tccacggaaa cagaaacccg ctcctgcaag gccttcacca cctcttcttg
    17281 atcctttgtc aaatggtaag gattcaagcc ctcagactct tcctcgtcac cggagattaa
    17341 actcattacc gcacccaacg ccttgaatgg agcggagaca atatatcccc accaagcctt
    17401 acgttgatgt tcactcatat aatcatacaa tgtagtgctt aactcctttt ccttatcggt
    17461 aacctctacc ggaaacaatt ccaacagaaa cggggtactc tgcaccacat ccggatacaa
    17521 atccggagag atcgcgtccg caccggcagc ggcattcaga ttaatcccag ccatagcagc
    17581 caaaccgcca agactagatt tttttgccgc atcctgtgtc tctggtgcca atttcaccgt
    17641 agttgtatat tccttgggaa tactgaaagc tacaatcaaa cctactacca ccgcaatacc
    17701 acagcctttc aataagaact tacgctcttt ccacagtttt tgcgccagtt cgattaaatc
    17761 gatctcctgc tcctcaggta actcttgtct ttttatctcg tttatcgtat ccatgcctga
    17821 ttagttttta atcatgttaa caatagaggt aatcatcgca gccatagagg tagcggagct
    17881 actgatactc atgatctcag ccaagcttcg gcgctcacgt tgcgttttcg tcggaactac
    17941 gatctcacag cccggctcca ctttcggata acgcttgaaa aagatagcgg tacgcttcgt
    18001 cgtagcgacc ttaccattca tatatattac gatcggatac ttacgtgcga tatcattata
    18061 accaccggct tgagacaagc aatccataac cgacatacct ttcgtgtaag ttacgctgtt
    18121 cggataagtc acggctccgc tcatcttcac cgtactttgc atctgcggga tataaagctc
    18181 atcgccgtca cgaagcacaa cgtcatcgat actacccgga tttgccaacg ctttctctaa
    18241 atcaatacct acggaatagt ccttcacatt catcaacgct acaccgatgg aatcccggct
    18301 ttgcttattc gcctcactta aagccagaag ggtctccatg cgtttcaatt catcttctgt
    18361 caactgacgt ttcaagctag caccttttac ataagactct ggggtaactc ctcccgcttt
    18421 cgcgataata tcactcaagc gagcgttctt cgtagccaat acatagctac cggcaaaagt
    18481 gatctcgccg ttcaccttca cgacctgttg ctcatgatac cccggggaga aacgaacata
    18541 aacctcatcg aacggctcca atgtgaagat cgtatctccc gcattcaact tgaagtcctc
    18601 actcaacgag aagttatata catcggcgat ccggttgaca ttctgattgg aactaggatc
    18661 cttcacacga cgggctacct ctacattaat agaagaagcg gactctctta aaccacctgc
    18721 catcatgata gcgtcttcta ttgtcaaatt atgacgatac ggaagcaccg tatccggata
    18781 attcacggct ccgccaacct tgatcgtata aggttcgcgc aaatcgaata gggaaggaat
    18841 gcttaattgg tcttccgctt gcaactccac atctggagcg gtaccgttca agataccacg
    18901 aatatccacg gcgatcatcg tagtcgtgaa atccggattc aaacgggtaa tcaaggcacg
    18961 gccggcgaac tcgtctcctt taagacctgc ggcctgtttt accaattgct ttaccgtacg
    19021 aaccgacgga cttaactcat attctcccgg acgccataca gctcccgtca cgaccaaacg
    19081 attctcataa aaaggaataa cggaatctac ctgcaaagaa tcgccatcct gcatcacgaa
    19141 agaagcgaac ttatcctccg aaaccgtaga gatctggtaa cgactatctg atttacgctt
    19201 cacttgtacg tccttcgtat aagcgtcgcc ggtaaatccg ccggccatat ccagcaattg
    19261 cttcaaggtc tcgcccttgc gcaactcgaa aatacgatta cgtttcacct tacctcgaac
    19321 caccgctaac tggtcgtacg ggcctaccat aatcatatcg ttctcttcca aacggacatt
    19381 cgttgtgtac tttccgttca ataaataatc atatacgtcg agattagcga tttccttgct
    19441 attacgatat accttgatgc tacgcaaaga accaatctta ttcacaccac cggcggcata
    19501 caacgcatta aataatgtgg cgaatgaagg taatgtatac gtaccgggag cgactacctc
    19561 gccgacaata ttcaccttca tgctacgaat ctggctcaaa ctgacggaaa caaaggtatt
    19621 cccctctccc gaaccagaca gcgtagacat aatctggctc aactcctgac gcagacgagt
    19681 ctcagcgcca gcgatcgtca atccactgac cgacaccgga cctaaatttg gtacaaggat
    19741 cgtaccgtcc ggagagatct ttaatttcaa gtttagctcg gaatctcccc atacattaat
    19801 caataactca tcaccagcgg aaagcacata atccttaggt gtagggatgt ttaaatctgg
    19861 ggcaaaagat aagttcttgt ttgagaagat ttcatgcccg aatacggtat tctccatggc
    19921 tgaagcagga agattatttc tacgttgggc ttctaaggat tgtccttcat cgattaccgg
    19981 cattacccgg tcgctaacct tcgcatcggt agcggtagct tgagatccga cagatccccc
    20041 ttcttgtttc atacgcttgg ctaattcctg ctgtatctgc gtatccgaca ttccagcggc
    20101 tttcgccttg tcaatcaagt cttgcggaac ctgcgcatac acagatcccg acagcaataa
    20161 gcaacatacg catagtacgt tcttaaacga taaattcata cagtctatta ttgtttttta
    20221 ttatatacca cccctgctat aagcgactaa cttaaaaaaa gcagctattc tctagatttt
    20281 cagctggcaa agataaagaa tctttttaat atatggctta aaaagtcacc gttaatccat
    20341 catatgagta atgtacatgc ggaggcaact ctttttcaac gaccgcatgc aaccctatgc
    20401 gatgactcat atggattaaa taggcctcct tgggctggat acgggatata ttcgctaagg
    20461 cttcctccag actctcatgc gattgatgct ctcctttccg aagagcatca ataaccaata
    20521 catcaaggtt ttccaactta gcgtactcct cttccggaag atatttaagg tcggtcaagt
    20581 aagccatatt gccgatacgg aaacctaaga tcggcagctt agcgtgcatt acacgaatgg
    20641 gagtgatcat gacaccggcg gcctcaaacg gtttcgtccc gatcgtatgc aataccaaat
    20701 taggcactcc cggatattta tgctcccgga acacataagg aatgcgagtt tttatcgcct
    20761 ccacgacatt gtcttccgca taaatatcca catctttata ccgaccaaaa gggcgtagat
    20821 catctaagcc acctacatga tcgtagtgct catgggttac taaaacggcg tcaaaatggt
    20881 aaatcttatt ggttatcatt tgccaacgga agtccggacc acaatcgatc aatacccgtt
    20941 tcccttccgt ctctaccaag atcgaggccc gtagacgcca atcacggggg tctttactag
    21001 tacatacctc acattggcaa cctatctcag gattgcccgt agacgttcct gttcctaaaa
    21061 aaacgatttt cattatccga catatttaac ctcaggcata agctctatac cgaaacgatc
    21121 ttttacggcg gtacgaatgc tctccgcgac caacgcgatc tcatcccccc gggcatctcc
    21181 taaattcact aataccaacg cttgtttctc gtaaacacct accgacccat ggtttttacc
    21241 cttaaaccca cattgctcga tcaaccaacc ggccggaacc ttgatctttc cttccgaagc
    21301 gggataagac gggatttccg ggaattgctt tttcaatttc tcaaaatgct ctgccgtaat
    21361 tatcgggttc ataaagaaac tgcctgcgtt gcctaatact tcaggatcgg gaagcttctg
    21421 cctgcgaatt gttatgacag cctcacggat cgtttccaaa gtaacttccg gatatttcgt
    21481 caactcctcc tttaagttcc cataattaac tgaaaaacca gggttcttgg atagtcgaag
    21541 cgtgatataa gttatgatgt gggggtcatg atgttcattc ttgaaataac tattacgata
    21601 tccatattca caatccgaat tcgtaaaagt ccgtttctcg aatgtcaact ggttataagc
    21661 ctccacgctc tcgatcacat ccttgatctc catgccataa gccccgatgt tctggatagc
    21721 ggcagcgccc gcctcaccgg gtattaaaga aagattctct atacctcccc aacctttcga
    21781 tacggcgtat gccacgacat catcccagat ctccgcagcc ccgacacgaa gcgatacata
    21841 ctcgtccgtt tccgccgaga tagaaatccc cttgattcgg gaatggatga taatgccatt
    21901 ataatcgttg atgaacaata gattgctccc gcctcctata tgcaaggata aacattcctg
    21961 aaagtattca tcatgtaaga ttcgttgcaa ctcctcctcc gtctcatact ccatgaacca
    22021 acgtgtcttt actgggagat ggaacgtatt gtgtttctcc aacgaataat tctgctctat
    22081 tctcatcgtc tattttattt ttagggcaaa agtagtcata aataactcat ccgcaaatta
    22141 tgtagttccg gattttttca gtagatttgt atatagagtt gatcgtatgg atgagaacac
    22201 gtccggcata tccggtgaaa tacagaagat gatcctcgac aagttaaaca cgttcaatcg
    22261 aggaaaaacg tcagacaaag ggcggtacta cattcttttg cctacctcaa agaccttata
    22321 ttatacgctt tggttcttta cgccttcggc cacttatcat ccgacggtct atttggcgaa
    22381 tctcgacttg aatgccatca gctcggtgaa taaggcgatt aagatggtaa gcaactcctt
    22441 tctaccttta tttataacga cagatatcaa agactctccc gataatggag acgatattat
    22501 ttctttcggt aaatacagag gataccattt gcatgacatc tatacgatcg atccccgata
    22561 cgtcgtttgg atagccgata aatatgaacc tcacgtaaaa agcgagatgc gttttaaaga
    22621 gttagcggtg acctacagta aaatctatct cgacctacag acccgtaaaa aatataaaat
    22681 gcctgtaagc cgctttgtag gaacaccggg agaaaaattg agcgatttaa agttaacaat
    22741 cacaaaagtc cgcattgaag acgattctta caagacacag attatccgtg gtaccgaata
    22801 tttctatgta gatcaattgc tcacggccgt ggacatcgcc ggaaattact tcttattgag
    22861 gataaaagcg aaagatcgta gtcttaccac gcaaacgttg ccaccgggcg ctcatgcttt
    22921 ccaagtaggg gaaaaattga ctttgacttc cgctaaagtc ttaaaacata tagaatcccg
    22981 tactatcaag tacacacgaa tcgggtatat caagattcaa taaatgtttc gaaattcgca
    23041 aacagacaca ttattaacat tttttgttct taaaaatgta acaaacatct gtaggccttg
    23101 tttaataaga aactcaaatg caaatgtatc tttgcaaaac gtaactataa aaccagcttc
    23161 aaagtgtaca tttgtagtgt ttaacaattt aaaaaatttg catttatgaa caaagcagaa
    23221 cttatagagg ctttagcaga caagaccggg ttacaaaagc aagaagcaaa gaaagtattg
    23281 gatgcttaca tcgagatcgt aactgagcgt atgtctgaaa atgaggaaat cgtacttgtc
    23341 ggatttggaa cactgatccc aagaccgcaa acacagcgtc ttgccagaaa tcctaaaaca
    23401 ggtactccgg taatgatccc cgctcgtacg accgtaaaat tcaaaccggg taaattcctc
    23461 cttgaggcga tgaatgccca cctgaaataa taaagtcacc gaaaacgtag taaaaatatc
    23521 cccggtaagg ggataaaaaa tcataagtat gaaatctttc atttataagt atgaatgaaa
    23581 aatttcatac ttatgatttt tagtgtccgg aaatgattac ttttgggctc aaaaaagact
    23641 catgagaatc gttaatcttg gagacaccaa ttccatatta aacaagttcg tagccgaact
    23701 tagagatgta gatatacaaa aagacagcct tcgcttccgt cgcaatgtcg agcgtatcgg
    23761 agaaatcatg gcttacgaga tcagtaagga atttcattac agtacgaaag acatccagtc
    23821 cccgctaggt atagccccga tgaatacgcc ggacgatcaa atcgtgatta gtacgatctt
    23881 gcgtgccggg cttccattcc accaaggttt ccttcggtat ctggataatg cggagaacgc
    23941 tttcgtatcc gcttaccgca aatataaaga ccgtttgaat tttgatattc atatcgaata
    24001 tatcgcctct cctcgcttaa caggtaaaac cttgatcata tccgacccga tgttggccac
    24061 cggaagttct atggaattgg cgtatgaggc cctgttgacc aaaggagtac ccggccatgt
    24121 acacgtagcc tccatcatct caagcaaaca agccttggaa tacttgcaga agaaaatgcc
    24181 ggatgacaag actacaatct ggatcgccgc attagataat gacctcgacg atcattctta
    24241 tatcgttccc ggattaggcg atgcaggaga tttagcgttc ggcgagaagg aatagggatg
    24301 tgtaaaccaa aacgtactgc ctttgcccaa ctcggaattt acaccgatcc gaccacctag
    24361 tctatttacg atggtctcgc aaatagatag ccccaagccc gtaccttgtt taaacgtatt
    24421 tcctttatag aaacgatcaa agatatgggc ttgtatctct tggctcatgc catcccccgt
    24481 atcagtcacg gagaatttta tctcatcacc tatgatctcg taagctaaga tgatacaacc
    24541 ttcgctcgta tacttgatcg cattgttaag gaaattggaa attacctgcg tcagccgcat
    24601 acgatcgcta tagatttggc attccggtga atctttggga gcaatcagag ctacgttatc
    24661 gggcatctta atacggaaag aggtcacgat ctcattgatc acctctttta tgctcatatc
    24721 ggcgaacttg aaatccatcg taccagattc aatttttgcc aaatctagaa tatcactgat
    24781 caattgaagc aacatccgat tattgctatc gatgatttcc acaaactcat gcctctcctc
    24841 gggatcatcc gtttccgcca ataattgaga aaaaccgaca atggcattta atggcgtacg
    24901 aatctcatga ctcatattcg ctaggaaggc agacttcaaa cgatccagtt cttccgccct
    24961 ttcccttttc aattgagagt cctttaactc cgtgatatca taattaatac agatcatctc
    25021 cggtttattc gggtctacgc tttgagggtt acgggtgata ttggcgcaaa tccatttcca
    25081 tccgtcacca gacttcacac gcacttccct acggaaatga tgcgctttac cctgtttcac
    25141 ctcctcaaag aatgagttta tatatccagc gtcgttcgga tgaatataag aataaatccc
    25201 aataatttgg gacaaggggg ttccatcctt ctctcccata ttctcatacc attgcttaat
    25261 ggcatagccc tcaaaggtat ataagtcata aagggcataa ccgactttag cgtatacgct
    25321 gaccaaggta aatacattct caaactcaga aatacggtta taggcgatca tcttttccgt
    25381 attatccaaa ttaataagta aatagctgga aggttcacct ctttggtcat ataaaatact
    25441 ggccttggta acgatatcca actcgcctac tttcgaggtg ttataataat catcgacctt
    25501 cttaaacgaa taattcagcc ggaaattcac ggatttattc tccttgagtt tcttgatcac
    25561 atctttaggc agaatcgggt tgctaaaaat attgactcct aaaacgtcct tctttgaccg
    25621 gataccgaat atctccatat cctttgcgtt cagatcaatc aagtaaccgt ccctgtcata
    25681 aagctcgact cccacaggta aatttacata cagctttcgg aagatcattt cattatgatc
    25741 gatcatctta ctaatctttt cctctttcag tttgaaatta ggtaaaatct gtaatatgcc
    25801 caacgctttt acgcacactc cgttattcaa cttacgctca cataatctgg agcgtaccca
    25861 tttttcccca gtcggtgtta ttatcggaaa tatttgctca tacgtatcga cagattggat
    25921 cgataaaaaa tccgtagtaa tcagatccct aaagtcttcc cggattatat agtaaaattc
    25981 aaaaaaagag agattattcc ccttcttccc aaatatactc attaaataat cggaacagat
    26041 ataacttctt tgaacaaaat cggcttccca caagccaact tccgccctat ccaataacaa
    26101 tttacattga tccaattgag tctgtatatc ctccataaaa atatcccttc cgataaaatt
    26161 acactatgat ttcacaaaga tataatttaa atagtataaa tcctctataa taaaaaagag
    26221 attgtctcga ataactcaag acaatctctt tctatattca aagcctaata taaattattt
    26281 caattccttg atacgaatat tgcggaattt gacaggggaa ccatgcccta agaaacctat
    26341 atgacctttt ttgttaaaca aacccggatg ctcctttcca tcaggcgcac cattcttcac
    26401 ggcatcccga atatttccat ccaagattac tactccattc accgtcacac ggatatgatc
    26461 gccatccgcc atgatctctt ccgtattcca ttctccaacc ggcttgaacg ctttcggatg
    26521 atcctcacgg gcgggaatga taccgtatac ggaaccgtga tgttgcagcg gagtgatgtt
    26581 tccttggtaa ataggatgtt cacaatccaa gacctgcact tccataccta catatgctgc
    26641 atctccttcc atcggcgtac gaataccgac accgttatta gctcccgggg ttaactggaa
    26701 gtcaaaacga tagataaagt ttccgtattc cttcttggtg tacagattac caccgaaact
    26761 actgcttggg accatagaga tacagccatc ttccaagata taatcaaccg tgtttccagt
    26821 ccactcatgc atattcgttc cgtcaaacaa aaccttgaag ccctcttttt cctcttccgg
    26881 cgataatttg aacggttctt gtttttccaa ttcctttacg tagatattac ggtaatagac
    26941 cttgctgcca tgagcttgca tctcgatttg ctctaccggg aaaatcggaa gcttgcgatc
    27001 ccaatagttt tccagaatca cgttatctac cactttttct ccgttcaaga caaccgtcac
    27061 acggtcacca accatcttaa tatagaagga attccattca cccaatttat tgtcggccac
    27121 tttcgaaggc ttgctctcgt ttacctgatt gttgtacaag ccaccggaac ctacttgcgc
    27181 accaacattt acccgagaag tatcccagat ctggacttga ggagtaccac gcagataaat
    27241 accggcatca gcctcagggc ctttcggatc caacatccaa tccacataca tctcgaaatc
    27301 accatattgc ttttccgtac ataggttatc gtacccagta ccgtcaaata ctaacaggcc
    27361 gttctctact ttccagtcac gacgcatatt ctcatctgcc ttctcctgcg ctttcgccaa
    27421 ttgagccggt ttcattttcg cgcgggcgat cggattctcg accaaacctt tccaacccgt
    27481 taaatcctta ccattaaaga tagagacaaa tccgacctcg tccggcatcg catccaaatg
    27541 ttgcttcaag gcatcgatat cataacgagc gtcttccccg tcaaacatgg tcaaaacacg
    27601 tttcaagata gccttcacat tgtcaccctt atattccgga tggttacgag cgatattcca
    27661 aaccgcataa acagccgcag aacgaacagc cgcatcgctt gaatccaaga attccgacgc
    27721 atacatcaat gccaagaagg tatccgcccg ttggatctga cgtaaaataa gagccttttg
    27781 ctcactcgtc cgggcaatct ccatgacttt ccgcaagctc aacaaacgat tctctctcgt
    27841 aaatgtcgga ttagatacca actgcacata acgctttaac gccctgtcga atacttgatc
    27901 ggaagcggct gattggcaaa ccttaaatag ttcgtcggca gcctcaatac ccttccaagc
    27961 caacaaagcg tcaagagccg catccttggc cgctccattt cctttattca atccttccac
    28021 gatcgtagcc aaagcctctt tctcgccagt cgctgataag accttataat aaagatatct
    28081 cttgctgtcc cccgcttgta tcatacgacg attcacgtta gatacttgag ttgccgccgg
    28141 ttgtttagag atggcggcaa tgatcgcatc ttgaagcgga gcgacagctg aagcctccgc
    28201 agtctccaac attccgcaca ataaagtgaa atctttctcg gatactacat ctttcaatgc
    28261 ggtataagcg gctttcttca cctctgagga gccggattta atctgatcca gtaccgtatt
    28321 tagattcgca tcggccatac gtatcgccaa cagctccaaa ccagcgattt ttccggcatc
    28381 ggaagcggac gggatcactt tagcgactgc ttgatcaata tcgccgttaa atgccatcaa
    28441 agcatcttga cccaataaaa tcacttgctt gtcattgctc ttcaacaaat cagccagcac
    28501 aggaatgaca ctcttatcac cgattttaac caaggcccaa acagcggcct gttgcacat
//
LOCUS       DBMDTB010000045        27896 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_617_length_27896_cov_11.336895, whole genome shotgun sequence.
ACCESSION   DBMDTB010000045 DBMDTB010000000
VERSION     DBMDTB010000045.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 27896)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 27896)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27896
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_617_length_27896_cov_11.336895"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..237
                     /locus_tag="ACZPB4_08850"
     CDS             <1..237
                     /locus_tag="ACZPB4_08850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HIR1098360.1"
                     /translation="FPDQEFGVVNGVVSNISLVPTDEYYTADIDFPEGLRTNYGIDLP
                     VSPETQASAEIVTEELRLIERFFLPIKRIVKEGF"
     gene            complement(293..436)
                     /locus_tag="ACZPB4_08855"
                     /pseudo
     CDS             complement(293..436)
                     /locus_tag="ACZPB4_08855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005786616.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            complement(540..1742)
                     /locus_tag="ACZPB4_08860"
     CDS             complement(540..1742)
                     /locus_tag="ACZPB4_08860"
                     /EC_number="5.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AGE family epimerase/isomerase"
                     /protein_id="HIR1098361.1"
                     /translation="MAAFDNLSNPSEYLAYWGKTYRNELLSNILPFWMKYGLDKENGG
                     YFTCVDRDGTLMDSTKSVWFQGRFAFILAYAYNHIEKNEEWLRACKNGIDFIEKHCFD
                     TDGRMFFEVTATGIPVRKRRYVFSETFAAIAMAHYALASGDKGYAEKAVNLFKQVLHY
                     KNTPGLLEPKFREGLVAKGHSFCMILIDTAARIREAINDPILTQQIDDSIAELRRDFM
                     HPEFKAILETVGPNGEFIDSIAGRTINPGHSIETAWFILEEAKYRGWDPQLKEMGLQI
                     LNWSWDWGWDKTYGGINYFKDCKNFPPQEYWHDMKFWWPQCEAIIATLYAYQATGDAK
                     YLEMHKLINDYTFNHLPDKEYGEWYGYLHFDGSLSQSAKGNLFKGPFHIPRMLLKCSL
                     LCDEILSK"
     gene            complement(1746..2663)
                     /locus_tag="ACZPB4_08865"
     CDS             complement(1746..2663)
                     /locus_tag="ACZPB4_08865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009126756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HIR1098362.1"
                     /translation="MDKIKGLIDAPFTPFYENGEVNYEPIEDYAKLLVKNGLKGVFIN
                     GSSGEGYMLTEEERMKLAEKWMEAAPEGFKVIVHVGSTCVKSSRNLAEHAQKIGAWGI
                     GAMATPFPRIGRIEELVKYCEEIACGAPALPFYYYHIPAFNNAFLPMLDFLKAVDGRI
                     PNFAGIKYTYESLYEYNQCRLYKDGKFDMLHGQDETILPCLAMGGAQGGIGGTTNYNG
                     KELTGILEAWAAGDLETARERQNFSQEVINVICNYRGNIVGGKRIMKLIGLDLGKNRT
                     PFRNMTDEEEAAMKAELEAINFFERCNKF"
     gene            complement(2805..4013)
                     /locus_tag="ACZPB4_08870"
     CDS             complement(2805..4013)
                     /locus_tag="ACZPB4_08870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HIR1098363.1"
                     /translation="MTTKFLLSSDDNTRSGLLKKKIIHYYMANGDATIAEVCKEMNLS
                     IPTVTKLISELQEDGYILDFGKQETSGGRKPSIYGLNPVSGYFVGVDILKDQLNLAIL
                     DFKGDKIRIEQNIPYTLENTPAALDHLCECINEFINSLPIPREKILSIGINISGRVNP
                     FAGYSYSIFYFEEKPLSQILEEKLHIKIYIENDTRSMAYGEYLQGVVKGEKNILFINI
                     SWGLGIGIIIDGKVYFGKSGFSGEFGHFSFFENEILCHCGKKGCLETGASGSALYRTL
                     LERYKEGSNTILASKIDAGEYIGLSDLIDAIHKEDMLSIEILEEIGFNLGKGIAGLMN
                     IFNPELVVLGGPLSQTGEYLSLPIKSAVRKYSLNLVTRDTQIKVSKLGERAGILGACL
                     LSRSKILGMI"
     gene            4147..5265
                     /locus_tag="ACZPB4_08875"
                     /pseudo
     CDS             4147..5265
                     /locus_tag="ACZPB4_08875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860494.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            5313..8588
                     /locus_tag="ACZPB4_08880"
     CDS             5313..8588
                     /locus_tag="ACZPB4_08880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SusC/RagA family TonB-linked outer membrane
                     protein"
                     /protein_id="HIR1098364.1"
                     /translation="MKKNLLLLMLALLLPAFMYGQEQTVSGTVLDTYNMGVPGASIVE
                     KGTTKGTITDFDGNYTLTVSNKNATLVFSFIGYKTQEIPVAGKAKVDVILQENAEQLD
                     EVVVTGYGGSQKRATLTTSISKLDNAVLENAAMSNAGQSLQGTVSGLRVVNTTGQPGA
                     NPNIVLRGGATITGKDNGALVVVDGIVRNSLADINPSDIESIQVLKDAASTAIYGARA
                     NGGVILVTTKRGKEGSASVSYKFKGGANFARTGYDYLNAHDYIYYNRLGYQRTGRSGM
                     DNQMGYGIGNDLFDIRYLDDSTKGLLAEGWQQMQDPTDPNKQILFKDYSGQMKDAAFQ
                     DPSFTQDHYINITGGNDKGTFAASLGYYKEDGLIKGTSYERFSGTFNGSYKIFPILTV
                     NAGTTYTWSRQPGLWIGSYEFFYRTMSQRPTWNPYMEDGSPASGFGTGDGNPLYYKDK
                     LTNTNGTRRSTYNIGFDLEIIPKKLILKENSALYHVDDQTDKFEKSYQQQNATSPNLT
                     RKAEAKYIKQNQQQHSVTLTYTDTFKEKHNLEAMLGGEYFNWHQYTLNARTENSPSDD
                     IPTLNAGSNRTYTYSYKEGYRILSGFARVNYNYNYKYLLSVVARYDGISKLSDNRWGF
                     FPGISAGWNIMEEEFFKESKLVDVISNLKPRISYGVNGNVNGLGYYDVYGSYGQKDAN
                     GSIITNYDGSVGFYNDKLVNGGLRWEQSKSFEVGLDIGFFNNRLSFILDYYNRTTSDL
                     LTDLDLPNYTGFNSIKTNLGTLRNQGFEMEVKANILNNVNGFSWDVSANLSTVANKIV
                     KLPANGNENNRQGGYQVYDPQKGEVVWVGGKQEGGKLGDLFAFKQDHIFKDWDDVKAN
                     ANNRYDAIGELYGPAAWEALKDKAGKQPIEPGDVCWADLNNDGVINNLDRVKVGNLFP
                     TVTGGFSTTLGYKDFSLYARFDYALGHTLYNDLAARSLGQYQGSFNIIDMVKDSWSET
                     NQDTDIPKFYYADQLSKKNITRSNNGLTAVDNNSSRFYEKGDYLALREITLTWNLPKK
                     WINKALMSNASVYVTGQNLFYITGYTGVSPEPAVDTTYGQGLDNGRYPTPKTVLLGLS
                     VTF"
     gene            8617..10188
                     /gene="nanU"
                     /locus_tag="ACZPB4_08885"
     CDS             8617..10188
                     /gene="nanU"
                     /locus_tag="ACZPB4_08885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SusD family outer membrane lipoprotein NanU"
                     /protein_id="HIR1098365.1"
                     /translation="MKKIIIAMMAAVSLLNFSGCDSLDMEPVSSISDANYWKSPDQFK
                     AFNIGLHGLLRSQSSYNIFVLGEPRSDIYGDQPFGGEATQGVERFSYNTINAEFTGIS
                     NFANFYTTLNQINLMIRRTNETDLLGEAEKNYYLGQAYGLRAYIYFHLLRSWGDVIIT
                     TEPTLGSELDISHLDKAASPASEVMDLIKKDIDASEKAFGGDYSYKQGKCYWSKPATL
                     MLKGEVYLWSGRQMGGGTGDYTVAKTALQDLQQNGNLKLQEKFTDVFSFNNKENSEMI
                     FALHSGKEDDFMMWRDYNWRNNMVPQREYMAGYCDETGTPFLEIPGYNLQGLMRYQVK
                     KDHYLKSFREGDTRLKGTLKAVYKKHEDGTLEYIAPIQYKFQGTTLEGSNERSWYDDY
                     PIYRYADALLLLAEAKALLGEDPSTEINAVRERAYGSEYFNAHKNEVAYPNDKGSFYN
                     DNPFEAGDENVMEAILKERLREFFFEGKRWYDLRRFGKDYVLKYTTAQESRLLWPINE
                     GALTNNPALKQTPGY"
     gene            10326..11951
                     /locus_tag="ACZPB4_08890"
     CDS             10326..11951
                     /locus_tag="ACZPB4_08890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BNR-repeat neuraminidase N-terminal
                     domain-containing protein"
                     /protein_id="HIR1098366.1"
                     /translation="MKKTFLYFCLLFIVQTAFAADSLYVREQQIPILIDRIDNVLYEM
                     RIPAQKGDVLNEITIQIGDNVDLSDIQAIRLFYSGVEAPSRKGEHFSPVTYISSHIPG
                     NTRKALESYSVRQDEVTAPLSRTVKLTSKQPMLKGINYFWVSIQMKPETSLLAKVATT
                     MPNAQINNKPIDITWKGKVDERHVGIGVRQAGDDGSAAFRIPGLVTTNNGTLLGVYDI
                     RYNNSVDLQEKIDIGVSRSTDKGQTWEPMRVAMTFKQTDGLPHGQNGVGDPSILVDEK
                     TNTIWVVAAWTHGMGNERAWWNSMPGMTPDETAQLMLVKSEDDGKTWSEPINITSQVK
                     DPSWYFLLQGPGRGITMQDGTLVFPIQFIDATRVPNAGIMYSKDRGKTWHLHNLARTN
                     TTEAQVAEVEPGVLMLNMRDNRGGSRAVATTKDLGKTWTEHPSSRSALQESVCMASLI
                     KVNAKDNITGKDLLLFSNPNTTKGRNHITIKASLDGGLTWPTEHQVLLDEAEGWGYSC
                     LSMIDKETVGIFYESSVAHMTFQAIKLQDLIHQ"
     gene            11961..13979
                     /locus_tag="ACZPB4_08895"
     CDS             11961..13979
                     /locus_tag="ACZPB4_08895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="family 20 glycosylhydrolase"
                     /protein_id="HIR1098367.1"
                     /translation="MRYILHFAIVLSFLYSGPLMARNPVLLPLPQKYVRTNASFHPKE
                     IAVSSEGKLRSILMEFLEELPVSVQPDSRYKIEVSLVDKLDGIPLNSEEAYQLSVSSR
                     GITIRAVSEQGAYWAIQTLRQLTERQGKRYSIQGCEITDWPAFRIRGFMQDVGRSYIS
                     MEELKREIEVLSRYKMNVFHWHLTENQAWRLESKIFPMLNDSCNMSRMPGKYYTIEEA
                     KELVRFCKEHNVLLIPEVDMPGHSAAFIRAFRHDMQSKEGMAILKLLMDEVCEVFEEV
                     PYLHIGTDEVKFTNPKFVPEMVAYIRAKGKQVISWNPGWKYKPGEIDMEQMWSYRGKA
                     RPGIPAIDSRFHYINHFDTFADLIGLYKSRIYNEPQGSHDLAGTILAVWHDRVVQPED
                     KLIRENNLYPNLLAIAERSWLGGGYQYFDKNGTMLPIDPDNEEHKAFVDFERRMLWHK
                     EHHFQGYPFAYVKQTNVRWRITDPFPNDGELTRSFPPEKSLQAQYTYEGKNYGTHDAI
                     GAGIYLRHVWGPLVPGAYKDPQPNHTAYAWTWIYSPKAQEVGTWIEFQNYSRSEMDLP
                     PMQGKWDYKESRIWVNDQEITPPVWTATHREKSNEIPLGNENCVSRKPTPVHLEKGWN
                     KVFMKLPVGTFNTPEVRLVKWMFTFVCVTPDGEKAVEGLVYSPDKQLK"
     gene            14001..16076
                     /locus_tag="ACZPB4_08900"
     CDS             14001..16076
                     /locus_tag="ACZPB4_08900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDSL-type esterase/lipase family protein"
                     /protein_id="HIR1098368.1"
                     /translation="MRKIIGILSIFLAFAFMSQAQKIKVACVGNSVTYGYGIKNRETN
                     CYPAQLQQMLGDAYEVENFGHSGATLLNKGYRPYTQQEAYQKALRFAGDYVIIHLGLN
                     DTDPRAWPNYRDDFVRDYLSLIESFRKANPRCKVWVCRMTPISHRHPRFKSGTRDWYW
                     MEQALIEEIARIAGATLVDLQEGLYDRPDLLPDALHPNAEGAGILARTVYGALTGDYG
                     GLQLPAIYSDRMVLQRDQPLPISGIANQGEKVTVTLAGQRKETVAGTNGKWTVTLDPL
                     RVSGKSYTLTVSTPSRTLNYRDVVAGEVWLCSGQSNMAFRVNESVKEEQQQQLDYAKQ
                     HSQIRLFDLKPRWETYAVEWDASVLDSLNRLQYYHDAQWEVCDTRNTARFSAIGFAFG
                     RMLADSLQVPVGLILNAVGGSPTEAWIDRKTLEFEFPDILQDWTKNDFIQDWVRERAA
                     LNIKQASNPLQRHPYEPCYLFEAGIQPLHRYPIKGIIWYQGESNAHNMKVHERLFPLL
                     VNSWRQNWNAALPFYYVQLSSIDRPSWTWFRDSQRRLAQTVSNTGMAVSSDRGDSLNV
                     HPTRKKEIGERLAHWALNKTYGHNVIPSGPLFRSATFTDNAAYITFDYAKGLTTSDGD
                     PIRTFEIAEQEGLYYPAQAVVENGKVKVWNDQVTHPKLVRYGWQPFTRANLINEAGMP
                     ASTFRAIKE"
     gene            16080..17270
                     /locus_tag="ACZPB4_08905"
     CDS             16080..17270
                     /locus_tag="ACZPB4_08905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclically-permuted mutarotase family protein"
                     /protein_id="HIR1098369.1"
                     /translation="MHNKQQITGWLFLLLLCVAGCGQPVSKKQNTMINWTKLPDLPGA
                     ADTASLGVSAPFAGIHNGVLIVAGGCNFPDKPVTEGGAKRYYSEIFVLLPEGWKEIDR
                     LPRPVAYGATVSTPEGIVCIGGNNSDSSLVEVSRISYNPTKGEVTVCALPSLPSPMDN
                     LSAAFTGQEIYVAGGNENGQPCHTFLRLNLANIEKGWEQLPDFPGAARVQPVLATGES
                     PNGTRIYLAGGFQPILNEEEPIVPTDVLVFDPATFTWQQETVLPPFKDGANRTLTGGC
                     AVTFQTDKILFMGGVNYDCFLAAIARPIHLAKAEAAQDSAAITRLQAEAKAYMHHPVE
                     WYRFNTTLLQYDLSTKAWSDLGEYEQLARAGAGAVIQDGRLTIINGELKPGIRTPQVN
                     QAKL"
     gene            17731..18342
                     /locus_tag="ACZPB4_08910"
     CDS             17731..18342
                     /locus_tag="ACZPB4_08910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HIR1098370.1"
                     /translation="MKTNIALLIEQSVNVIDSLNKGLRLTHKEQQFFCEHFEREEIKK
                     NEFTIRIGDYEKYLYFIESGILRYWTAQEYGDPDKEVTFWFSFPGEFANSYFSLKENQ
                     PSLIHIQALTDCVIWKLSKQDLADLYQTSLNINKIARIVLEDALCRKITRETLLLGSS
                     AEAIYEDLITKEKELINNIPLKYLASYIGVTPQRLSQIRRKVH"
     gene            18513..19766
                     /locus_tag="ACZPB4_08915"
     CDS             18513..19766
                     /locus_tag="ACZPB4_08915"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HIR1098371.1"
                     /translation="MQNEFDNMTLKDFENRGQDLLTRAKQVDDYISYRHRIQHLPYRV
                     ISLTGSSAHMRVIDPYSNKEKEMISFVSNDYLGLSHHPEVIKAGIDALEQYGAGAGAS
                     PLIGGHNFLHEQLEQEIAHFLKNEYAITYTSGYAANCSTLLAMMGKEDIAIMDMFTHA
                     SVFDGCLCTNTKRFLHNDIDSLVHVLNNAKSFKNRFVIIDGVYSQDGDIAFLDQIYTV
                     CKEHDAFLIVDDAHGIGVLGKTGRGIIEDYDLLDKVDIITGTFSKAFGCVGGYAIARK
                     EIITLLRYYSRQNIFSAAATPQTAASAIKAIQLIDQEPQWRNTLADNIEYFKTGLETL
                     GLDYGNTESAIFPVMVRNEHYVKEAARILFEQGIYVNPISYPAVPEKLSRLRFSLTAM
                     HTKEELDKTFSILENIRKKYKLAQI"
     gene            19986..20756
                     /locus_tag="ACZPB4_08920"
     CDS             19986..20756
                     /locus_tag="ACZPB4_08920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4377 domain-containing protein"
                     /protein_id="HIR1098372.1"
                     /translation="MKTRHLLNILLLALYTSSCNKEDTPLIKTETVKIFLLSETNRIQ
                     NEDIENHEYILAKEENQVDFQEINISAIEGFHYEKGYEYELLVEKKTLVNTNFDNNQT
                     KYKLIELISKNKVDFKYLIITKENPFILHSAGGRFEIPLQCIKEKYINNKLSEKEHHP
                     LKGLKYKIGTNYGGITNIVKEGKEIGFYKIIIERYGAYNMNGIPEWFCAFYTKNANLN
                     FDLKPSPIYEQIFEQPQTKGEQYLILPIINISIGTFDI"
     gene            20822..21940
                     /locus_tag="ACZPB4_08925"
     CDS             20822..21940
                     /locus_tag="ACZPB4_08925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015485 - cholesterol binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-activated cytolysin family protein"
                     /protein_id="HIR1098373.1"
                     /translation="MKKEIFILLTASLVVSSCVDNEDIYKNPDNSKKDQVLTLSKYPQ
                     KVIDIETGSKEHLALLNATTRSTFLIKDSVWPDKKGHSLIYETNEHGTTANTMRYIYL
                     GSLLKGGSLEEQRFQRLTNELDPLYISYSFPAKIVGDIIEKPSLQSQRTSLSKIMNQE
                     GMTGKQIVSFIYDMNQFTYYNELKLAFNCNIDVASVFNISTSVAQGKIRKKCGLVAKF
                     IQKNFTVDLDLPADGCLLKNNNELSNVGPYDPVYISSITYGRMGVMMFDSSYAYDSLR
                     VAVKAAFDAKIINGKLELTSEQTKIISEADLKIAIISGDGSYSVKTVDGINGFKEFII
                     AGGEFSKDVPGDPIFYSASYLSDDSPFYAKFRVNIPYK"
     gene            21948..23516
                     /locus_tag="ACZPB4_08930"
     CDS             21948..23516
                     /locus_tag="ACZPB4_08930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015485 - cholesterol binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-activated cytolysin family protein"
                     /protein_id="HIR1098374.1"
                     /translation="MRITSIFLFTIIIFGGLSCSNDDSLIHNKTKGILEKYPEPTVTI
                     TAHNHIPFLAKNILEEKAITKSVNIISDIAWANGFGRTITARSDEMVIPDNMNRYIYP
                     GSILEASSIAETRFTPIPVKNNPVHVSVSFPAKKVGGTIKEPSLLNIRQFVMDLMQQN
                     NIGKQSATLSFDVQKFVSYDELKMTFGSNENTGLLFWGTSSAQYQNKYRIIRSSGLCI
                     KFIQKYFTLDMDIPSNGLISGTIPGGYSPVYVSSIAYGRIGILTLETNYDYEKANKLV
                     KETFNSLFINKNNTLTKEQEAFFNSAEMKVFIAGGSGVTGVKTIGGIKEFTNYITEGG
                     EFSASSPGKPIFCSFANYSDDSPYRINFKIDIDSDPVYARLEYDITKDVSGGNVKSWY
                     TDANVYLRFYADKACSIKTIAQNYIGFNINRLILQQYVGPNYSVSKAREVKLDQNLTF
                     HNQTKGIEYPIAYGHRMTETIGTTYLDRGNWTNDHFYLRAGKFYQVRPPINMKYTCFI
                     DYHNQNEYDCSDFE"
     gene            complement(23641..24471)
                     /locus_tag="ACZPB4_08935"
     CDS             complement(23641..24471)
                     /locus_tag="ACZPB4_08935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HIR1098375.1"
                     /translation="MKKLGLLMMLLLLSRIALFCQAQTAGIEEKEVLRNEDVIFHQID
                     EHTWFGTGHLMANESLYLVEGETKAILIDAGTKIKDLDKLVASITDKPVTLVATHVHP
                     DHTGSAIDYFPEIYINPADTIGIPEFMPNYKGKVCFLTDGEILDLGGRTLEVVFTPGH
                     TPGSTTFVDKDAAYGFSGDSFGSGNLLLGVDFSTLISTCKKMSAVIEKYDIKYLYPGH
                     YFGMNKETPQRVKDMITMSEDILSGKAQGEPNPQGMLGLDRVYTKYGVRINYKKESMK
                     "
     gene            complement(24493..25095)
                     /locus_tag="ACZPB4_08940"
     CDS             complement(24493..25095)
                     /locus_tag="ACZPB4_08940"
                     /EC_number="3.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016799 - hydrolase activity, hydrolyzing
                     N-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0009691 - cytokinin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LOG family protein"
                     /protein_id="HIR1098376.1"
                     /translation="MEEKKINNISSVCVYCASSTKIPPIYFDAAKELGCLLGERKLRV
                     VNGAGNIGLMCTVSDAALAAGGTVTGVIPHFMVEQDWYHKGLTELIEVETMHERKQLM
                     ANLSDAVIALPGGCGTLEELLEIITWKQLGLYLNPIVILNINHYYDPLLELLRNAMNE
                     NFMRPQHAKMWAVADTPEEAIRLIYAEPKWDASLRKIAAI"
     gene            complement(25102..25848)
                     /locus_tag="ACZPB4_08945"
     CDS             complement(25102..25848)
                     /locus_tag="ACZPB4_08945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02757 family protein"
                     /protein_id="HIR1098377.1"
                     /translation="MDTKTISLLREWAKTYNTESFIKDDPVRFPHRFTEKRDIEISAF
                     LTAWISYGRRAHILQKAEELHRLMGESPYEFIRTGETSFAPLRNRPVRRRDTFYRFYT
                     YHDLHLLCCRLKDIYDTYDCMEDAMAAAGPCEDPILRLQQLFADLNGIPVLHGTSACK
                     RLAMFLRWMVRTDGIVDLGIWRTAVHPRQLIIPLDTHVHQISLRLGLTGQKTATLRTA
                     REITDALAKVFPDDPCLGDFALFGYDINQE"
     gene            complement(25850..26557)
                     /locus_tag="ACZPB4_08950"
     CDS             complement(25850..26557)
                     /locus_tag="ACZPB4_08950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006307 - DNA alkylation repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HIR1098378.1"
                     /translation="MTAAFILSELQSVGTPEKAVHLSRFFKTGPGQYGEGDQFLGVVV
                     PQTRSIAKANKATPFDELQLLLDSPWHEARLCALLILVYRFQDRKAMPEEREAIFRFY
                     LKNMRRCNNWDLVDLTCRDIVGEYLVDKDRSLLYRLAESENLWEQRISIVSTWAFIRR
                     NDFGDTLELSERLIGHKHDLMHKAVGWMLREVGKKERQTLTDFLERNATRLPRTALRY
                     AIEHYPEPERQYFLKKK"
     gene            complement(26554..27513)
                     /locus_tag="ACZPB4_08955"
     CDS             complement(26554..27513)
                     /locus_tag="ACZPB4_08955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacid dehydrogenase family protein"
                     /protein_id="HIR1098379.1"
                     /translation="MKILVTYDMFREGFTELESKYEVTFPEGRDFTYEEVFEMIPEYD
                     VLCSMFDFPVNKELIDHASKLRLIANYAVGYNNIDVAYALEKGLTVANTPDPVTAPTA
                     NIALGLMLDTARRITECDRKLRTLGKDMKVGVLENLGMPVTGQTLGIIGMGRIGKALA
                     KRANALGMDVIYHNRRQLCIEDETKLNVTYVSKEELLAKADFVSLNAPYTPDTYHILG
                     EEEFKQMKPSAILINTARGPLVDEHALVKALREGTIHGAGLDVFEFGDYPLPELLEMD
                     NVVLTPHIGTQTMETRIIMARTVCNNVIGFLEGDRPVSRVLRP"
     gene            27598..>27896
                     /locus_tag="ACZPB4_08960"
     CDS             27598..>27896
                     /locus_tag="ACZPB4_08960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016274990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098380.1"
                     /translation="MVLNYIWIAFFLIAFVVAVGKLVIGGDTAVFTEIINASFASAKT
                     GFEISLGLTGILSLWLGIMKIGEKGGVIQAFARLAAPVFSKLFPDIPRDHPVTGS"
BASE COUNT         8310 a         6223 c         6085 g         7278 t
ORIGIN      
        1 ttcccggatc aggagtttgg agtggtaaac ggcgtggtat cgaatatctc attggtcccc
       61 accgacgagt actatacggc ggatatcgat tttccagagg gcctgagaac caattacggt
      121 atcgacctgc ccgtctcgcc cgagacgcaa gcctctgcgg agatcgtaac ggaagaatta
      181 cgcctgatcg aacgattctt cctcccgatc aaacggatcg tgaaagaagg attttagtgt
      241 aatattatcc tttctttcct atgcgtttat cacagatgtc acgagtgaca gagtccgccg
      301 cagactctag ttccacgata tccaccatca tagctgattt catggttgat agcatctggc
      361 gatccatata gttcagtaag gcgacaaccc atagtaaacc gactacgatc caaggatata
      421 atttcttatt tttcatttga ttgaggaaaa taaaaaggaa aacaaagcct tagaaacatc
      481 aggagccacg gttgtgaccc ctgatgtcaa ttgaccaatt ttcagtattt tagataaagt
      541 tatttagaaa gaatttcgtc gcagagtaaa ctacatttga gaagcattct aggaatgtgg
      601 aacggacctt tgaatagatt gcctttggca gattgagaga gactaccatc gaagtgtagg
      661 tagccatacc attccccata ttctttgtcg gggagatgat taaatgtgta atcgtttatt
      721 agtttgtgca tttcgagata tttggcgtcg ccagtcgctt ggtaggcgta aagcgtagcg
      781 ataatcgcct cgcattgtgg ccaccagaac ttcatgtcgt gccaatactc ttggggaggg
      841 aagtttttgc aatccttgaa atagttgatt ccgccgtacg tcttatccca gccccagtcc
      901 caagaccagt tgaggatttg taagcccatc tcttttagtt gggggtccca tcctcggtat
      961 ttggcctctt ccaagataaa ccatgcggtc tcgatggagt ggccgggatt gatggtacgc
     1021 ccggcgatag agtcgataaa ctcaccgttg ggtcctactg tctccaagat agccttgaat
     1081 tcgggatgca tgaaatcacg gcgtagctcg gcgatggaat catcgatttg ttgtgtaagt
     1141 atgggatcgt ttatagcctc acggatgcgt gccgccgtat cgatcagtat catgcagaaa
     1201 gaatggcctt tcgccacgag accttcacga aatttaggct ccaataatcc cggggtattc
     1261 ttatagtgta atacttgctt gaataagttc acggccttct cagcatagcc tttgtcgcct
     1321 gatgccaatg catagtgagc catagcgatc gccgcgaaag tctcggagaa tacgtaacgg
     1381 cgtttacgta cagggatgcc tgtcgctgtc acctcgaaga acatacgtcc gtccgtatca
     1441 aaacaatgtt tctcgatgaa atcgataccg tttttacagg ctctcagcca ttcttcgttc
     1501 ttctcaatgt gattataggc atatgccaag ataaaggcga atcgtccttg gaaccaaacg
     1561 gatttagtgg agtccatcag agtaccatcc cggtctacgc aagtaaagta accgccgttc
     1621 tctttgtcca gtccgtattt catccaaaaa ggaagaatat tggaaagaag ctcattccga
     1681 taggtcttgc cccaataagc tagatattcc gatggattag ataaattgtc aaacgctgcc
     1741 ataccttaga atttattaca tctttcaaag aaattgatag cctctaattc cgctttcatt
     1801 gcggcctctt cttcgtccgt catattccgg aacggggtac ggttcttgcc gagatctaat
     1861 ccgatcaatt tcatgatgcg ttttcctccg acgatattac cacggtaatt gcagataacg
     1921 ttaataacct cctgagagaa gttttgtctc tcgcgagctg tctctaagtc accggctgcc
     1981 caagcctcta ggataccggt taattctttt ccgttatagt ttgtggtacc accgatacct
     2041 ccttgcgctc cacccatcgc aaggcaagga agaatcgttt catcctgtcc gtgcaacatg
     2101 tcgaatttac catccttgta taaacgacat tgattgtatt cgtataagct ctcgtatgta
     2161 tatttgatac cggcgaaatt agggatacgc ccgtctactg cttttaagaa atccagcata
     2221 gggaggaaag cgttgttaaa cgcagggata tgatagtagt aaaacggtaa ggcaggagcg
     2281 ccgcaagcga tctcctcgca gtactttacc aattcctcaa ttcgaccgat acgagggaaa
     2341 ggggtagcca tagcgccaat accccaagcg ccgatctttt gagcatgttc cgctaaatta
     2401 cggctagact taacgcatgt gctacctacg tgcacgatta ccttaaagcc ttccggagct
     2461 gcttccatcc atttctcggc caatttcatg cgttcttcct ctgtcagcat ataaccttct
     2521 ccggaagaac cattgatgaa tacgcctttc agcccgtttt tcacaagaag tttcgcataa
     2581 tcttcaatgg gctcgtaatt aacttccccg ttctcgtaga acggagtaaa gggagcatcg
     2641 atcaatcctt taattttatc catatctgcg ttatttttat gagttttaac ctctgatttt
     2701 aattatgctg caaatataaa taaaatattt taataatata gtggtgtttt atcgagaaaa
     2761 tgaaataatt atttattttt tatttaattc ctttgaaata catattaaat catacctaga
     2821 attttagatc gagatagcag gcaggctcct aatatacccg ctctttcacc taatttggat
     2881 actttgatct gagtatcacg ggttaccaag ttcaaagagt acttcctgac ggcactttta
     2941 ataggtaggc ttaaatattc tcccgtctgc gacaaggggc cgcccagtac gaccagttcc
     3001 ggattgaaaa tgttcatcaa tccggctatt cctttaccta gattaaaacc gatctcctcc
     3061 agtatctcaa tggatagcat atcctctttg tgaatggcgt cgatcaagtc agagagcccg
     3121 atgtattccc cggcatcgat tttactggcc aatatggtgt tgctaccctc tttataccgc
     3181 tcaaggaggg tacggtatag ggcagaaccg gaagctccag tctcgaggca tcctttttta
     3241 ccgcaatggc aaaggatctc attctcgaag aagctgaagt gcccaaattc tccggagaaa
     3301 cctgatttcc cgaaataaac cttgccgtct atgatgatac cgatacctaa tccccaagat
     3361 atattgatga ataggatatt tttctctcct tttacgactc cttgaagata ttcgccgtaa
     3421 gccatggaac gggtgtcatt ctctatatag atctttatat gtagtttttc ctcaaggatt
     3481 tgagacaagg gcttctcctc aaagtaaaaa atgctatagc tatatccggc gaaaggattt
     3541 acccgtccgg atatattaat gccaatgctt aatatctttt cccttgggat cggcaacgag
     3601 tttataaatt cattgatgca ttcgcaaaga tggtctaaag cggctggtgt gttttcgagt
     3661 gtataaggga tattctgctc aatgcggatc ttatctcctt taaaatctaa tatggctaga
     3721 ttcagttgat ctttcagtat atctacgccc acaaaatagc cggatacggg attgagcccg
     3781 taaatactag gtttacgccc tccgctagtc tcttgttttc caaagtcgag tatataaccg
     3841 tcctcttgta attcgctaat tagcttagtg acggtgggga tactgagatt catttcttta
     3901 catacctccg ctatagtagc gtctccattg gccatataat aatgtatgat cttctttttc
     3961 agaaggccac tgcgagtatt gtcatcggac gagagcaaga acttagttgt catggttata
     4021 cctttattga gtgattaggg caaaggtaca ataagttttt tcaaaaacta agcgtaataa
     4081 aataaaattt tttcataagg agctatctta attgtaagaa tttgtaatag aagttgaata
     4141 ccatagtctg cggcgaactt cggacgtttg atggcggtct tcctctggat ctacggattc
     4201 atgagccctg tggccggtat ggtggcagac agggtaaaca ggaagtggct aatcgtgggt
     4261 agcttatttg tctggtcctt cgtgactttg atgatggggt attgcacgga tttcaatcag
     4321 atctattacc tacgtgcctt gatgggggtc agtgaggccc tgtatattcc tgccggatta
     4381 tcgcttatca cagattatca ccaagagaaa acacgctcat tagccgtagg tatccatatg
     4441 acaggtctat acgtaggcca agccttgggg ggattcggag ctacggtggc cagcgcttat
     4501 acgtgggaaa cgactttcca ttggtttggt atcatcggca tcgcttatag cgtggtcttg
     4561 atcatcttct tacacgataa gaaagatcat gtggaacaag ccgtaaaact ggaaaattat
     4621 ccgaaagaga atccgatttc cggtgcgttt aaaggattag ggatgttatt cacgaacatc
     4681 gctttttgga tcattcttct ttatttcgcc acgccgagct taccgggttg ggcgacaaag
     4741 aactggctcc ctaccctatt cgctgaaaat ctctcgttgg atatgtccga ggccggtccg
     4801 ttatctacat tcacgatcgc tatctcttcc tttatagggg taatcgccgg aggtatttta
     4861 tccgataaat ggatccagcg gaatgtccgg ggacgtgtat acacaggcgc catcggtttg
     4921 gcattaacga taccctctct cctattacta ggatttgggc acaacttccc gatgattatc
     4981 ggcggtggtc tttgcttcgg tatcggttat ggtatattcg acgccaataa tatgcctatc
     5041 ctttgccaat tcatctcccc ccgttatcgg gctacagcct atggaattat gaatatgacc
     5101 ggtgtatttg ccggagccgc catcacggat atactaggaa aatctaccga cgctggtaat
     5161 cttggccatg acttcgccat gctagccgga ttggtactca tcgcactttt aatccaagtg
     5221 atcttcttac gtccgaaagt cgctaatatg accgacgaat gctaattaat ctcatccaat
     5281 aaactaaata aacaacaaaa aagtaattca ttatgaagaa gaatctactg ctcttaatgc
     5341 ttgcgctcct acttccggca tttatgtacg gacaagagca gacagtctcc ggaacagtgc
     5401 tggataccta taacatgggt gtccccggtg cgtctatcgt tgaaaaaggc acgacaaaag
     5461 gaacgattac cgatttcgac ggtaattaca ctctcaccgt atccaacaag aacgccacat
     5521 tagtattttc tttcattggg tacaagacac aagaaattcc agtagctggg aaagccaaag
     5581 tagacgtgat cctacaagaa aacgccgaac agctagacga agtagtggta accggttacg
     5641 gtggctcaca aaagagagcg accttgacaa cctctatctc taaattggat aacgccgtac
     5701 tggaaaacgc agcgatgtct aacgccggac aatccttgca aggaaccgta tctggtttgc
     5761 gcgtcgtaaa cacgaccggt cagccgggag caaacccaaa tatcgtactt cgtggcggag
     5821 ctaccataac aggtaaggat aatggcgcat tggtcgttgt agatggtatc gtgcgcaact
     5881 cattggccga catcaacccc tccgacatcg agtctatcca agtattgaaa gacgcagcct
     5941 caaccgctat ctacggtgcc cgtgccaatg gtggcgtaat cttggttacc acgaaacgtg
     6001 gtaaagaagg atccgcttcc gtctcttaca agttcaaggg aggtgccaac tttgctcgca
     6061 caggttatga ttacttaaac gctcacgatt atatttacta caatcgctta ggataccaaa
     6121 gaactggacg ttcaggcatg gataaccaaa tgggatacgg tatcgggaat gacctatttg
     6181 atatccgtta tttggatgac agtaccaaag gcctcttggc agaaggttgg caacaaatgc
     6241 aagacccaac cgatccgaat aaacaaatct tattcaagga ttactcaggg caaatgaaag
     6301 acgcagcctt ccaagaccct tctttcacgc aagatcatta tatcaatatc acaggaggta
     6361 acgacaaagg tacattcgca gccagcttag gttactacaa agaagacggt ctcattaagg
     6421 gaaccagcta cgagcgtttc tccgggacat tcaatggatc ctataagata tttccgatct
     6481 tgacagtcaa cgctggaacg acttatacat ggtctcgcca gccgggtctt tggatcggat
     6541 catatgagtt cttctatcgc acaatgagcc aacgccctac atggaaccca tacatggaag
     6601 acggatctcc cgcttcaggc ttcggcacgg gtgatggaaa ccctctttac tacaaagata
     6661 aattaacgaa tacgaatgga acccgccgct ctacctataa tatcggtttt gatctagaga
     6721 tcatcccgaa gaaattaatc ttgaaagaga atagcgccct ataccacgta gacgatcaaa
     6781 cagataagtt cgagaaatct taccaacaac aaaacgccac tagcccgaat cttacccgta
     6841 aggctgaggc caaatatata aagcagaacc aacagcaaca tagtgttact ttgacgtaca
     6901 cagacacatt caaagaaaaa cacaatctgg aggcaatgct tggtggcgag tatttcaatt
     6961 ggcatcaata tacgctgaac gcaaggaccg aaaattctcc gtcggatgac atccctactt
     7021 tgaacgctgg tagtaatcgt acctatacct atagctacaa ggaaggctat cgtatccttt
     7081 ctggctttgc ccgtgtaaac tataactaca attacaaata cctgttatcg gtcgtagctc
     7141 gttatgacgg aatctccaag ttgagcgata accgttgggg cttcttcccg ggtatctccg
     7201 ctggttggaa tatcatggaa gaggagttct ttaaggaatc gaagttggta gatgtgatct
     7261 ctaacctgaa gcctcgtatc agctacggcg tgaacggtaa cgtaaacgga ttaggatact
     7321 atgacgtata tggcagctat gggcagaaag atgcgaacgg atcgatcata acaaactatg
     7381 atggctctgt aggtttctat aatgacaaat tggtaaacgg tggattacgt tgggagcaaa
     7441 gtaaatcttt cgaagtaggt ttggatatag gattcttcaa caatcgcttg agctttatcc
     7501 tagactatta taatcgtacg acttccgatt tgttgacaga tttggattta cctaattaca
     7561 ctggtttcaa cagcatcaaa accaacttgg gaactttacg taaccaaggt ttcgagatgg
     7621 aagtaaaagc gaatatccta aacaacgtaa acggattcag ttgggatgta tcagcaaact
     7681 tatctacggt agcgaacaag attgtcaagc ttccggccaa tgggaacgaa aataaccgcc
     7741 aaggaggtta ccaagtatac gacccgcaaa agggtgaagt cgtatgggtt ggcggaaaac
     7801 aagaaggagg taagctgggt gatttatttg ccttcaagca agatcatatc ttcaaggatt
     7861 gggatgacgt gaaagcgaat gccaataacc gctacgacgc aattggagaa ttgtatggcc
     7921 ccgccgcatg ggaagcttta aaggataagg caggtaagca accgatcgag ccgggtgacg
     7981 tttgttgggc cgacttgaac aatgatggcg taatcaacaa tctagaccgc gtgaaagtag
     8041 gtaatctttt cccgacagta accggtggtt tctccacgac attaggctat aaagatttct
     8101 ctttatacgc tcgttttgat tatgcgttag ggcatacgct gtataacgac ttagccgcac
     8161 gttcacttgg acaatatcaa ggttcgttta acatcatcga tatggtgaaa gacagttggt
     8221 cggagacaaa ccaggatacg gatataccta agttctacta tgccgatcag ttgagcaaga
     8281 agaatattac tcgctccaac aatggtttga cagcagttga caacaacagc tcccgcttct
     8341 acgaaaaggg tgattatcta gctttacgtg aaatcacatt gacttggaac ctaccaaaga
     8401 aatggattaa caaagccttg atgagcaatg cctctgttta tgtaaccgga caaaacttgt
     8461 tctacatcac aggatatacc ggtgtatctc cggaaccggc ggtagatact acctatggtc
     8521 aaggtcttga taacggtaga tacccaactc ctaaaacggt tcttcttggt ttatccgtaa
     8581 cattttagtc aaacccatta aaaaagacag acatttatga aaaagataat tatagccatg
     8641 atggcagcag tctcattact gaatttcagc ggatgcgact ccttggacat ggaacccgta
     8701 agtagtattt ccgacgcaaa ctattggaaa tccccggacc agtttaaggc attcaacata
     8761 ggtttacacg gattgctccg ttcacaatcc agttataaca tattcgtatt gggcgaacct
     8821 cgctcggaca tctacggaga tcagccgttc ggaggcgagg ctacccaagg cgtagagcgt
     8881 ttctcataca acacgatcaa cgcagagttt acaggaatca gcaacttcgc taatttttat
     8941 acgacactga accaaatcaa cttgatgatc cgtagaacga acgagaccga tttattaggc
     9001 gaggccgaaa agaactatta cttagggcag gcttacggtt tacgcgccta tatctatttc
     9061 catttgttac gctcttgggg agacgttatc attactacag agccaacctt aggtagcgaa
     9121 ttggatatct ctcaccttga taaggccgct tctccagcga gtgaggtgat ggatctgatc
     9181 aagaaggata tcgatgcctc ggaaaaagct tttggcggag attattctta taaacaagga
     9241 aagtgttatt ggtctaaacc cgctaccttg atgctgaaag gtgaggttta tctatggagc
     9301 ggacgccaga tgggtggcgg cacgggcgat tataccgtag ccaagacagc cttgcaagat
     9361 cttcaacaaa acggcaactt aaagctgcaa gagaaattca cggacgtttt ctctttcaac
     9421 aataaggaga acagcgagat gatcttcgca ctccatagtg gtaaggagga tgatttcatg
     9481 atgtggagag actataactg gcgtaacaat atggtacctc aacgtgagta catggcaggc
     9541 tactgtgacg agacaggaac tccattcctt gaaataccgg gatacaacct acaaggctta
     9601 atgcgctacc aagtaaagaa agatcattac ctaaaatcat tccgcgaagg tgatacccgc
     9661 ttgaaaggta ccttgaaggc cgtttataaa aagcacgaag acggcacctt ggagtatatc
     9721 gcgccaatcc aatacaagtt ccaaggaacc accttggaag gtagtaacga gagaagttgg
     9781 tacgatgatt atcctatcta tcgctatgcg gatgccttgc tattattagc cgaggctaag
     9841 gccttgctcg gagaagatcc ttctacagag atcaacgccg ttcgcgagcg tgcttacggt
     9901 tccgaatatt ttaacgcaca taagaacgag gtggcttatc cgaatgacaa aggaagtttc
     9961 tataacgata acccgtttga ggcgggcgac gagaatgtga tggaagctat ccttaaagag
    10021 agacttcgcg agttcttctt tgagggtaaa cgttggtacg acttgagacg cttcggtaag
    10081 gattatgtat taaaatatac cacagcacaa gaatcacgtt tattatggcc gatcaatgaa
    10141 ggggcattga caaacaaccc cgcattgaaa cagactcccg gatactaatc gtacataggt
    10201 ttaaggcgat tggatataac taggtttttg gcacgaattc caaaggggct ttgttcatat
    10261 gaatgaatat cgctaccttt ggaattcaca tatctattaa tttcaaccta caaacaaaaa
    10321 acatcatgaa aaaaactttc ctgtatttct gccttctttt catcgtacaa acggcttttg
    10381 cggcagacag tctttatgtg cgagagcaac aaatccccat cttgatagac cggatcgaca
    10441 atgtacttta cgagatgcgg ataccggccc aaaaagggga tgtattaaac gagatcacga
    10501 tacagatcgg agacaatgtc gacctgtcgg acatccaagc gatacgtcta ttttatagcg
    10561 gagtggaagc tccatcccgc aaaggggaac atttcagtcc cgttacgtac atatccagcc
    10621 atataccggg aaatacccgt aaggctcttg aatcttattc cgtacggcaa gatgaggtta
    10681 ccgccccctt gtcgcgcacg gtaaaactaa cctctaagca accgatgctt aaaggcatca
    10741 actatttctg ggtaagtatc cagatgaagc ctgagacttc cttattggca aaagtagcga
    10801 ccacgatgcc taacgcacag atcaacaaca aaccgatcga catcacttgg aaaggaaagg
    10861 tggacgaacg ccatgtaggt atcggcgtac gccaagccgg ggatgacgga tcggcggcct
    10921 tccgcatccc gggattagtg acgacgaata acggaacatt actcggagtc tacgatattc
    10981 gctataataa cagcgtggac ctacaagaga aaatcgatat cggagtaagc cgcagtaccg
    11041 ataagggaca aacttgggaa ccgatgcgag tagccatgac tttcaaacaa acggatggcc
    11101 tgccccacgg acaaaacggc gtgggagacc catcgatctt ggtagacgaa aagaccaata
    11161 cgatctgggt agtagccgca tggacgcatg gtatgggtaa cgaacgggct tggtggaact
    11221 ccatgccggg aatgacaccg gacgagaccg cccaacttat gctcgtgaaa agtgaggacg
    11281 atggtaagac gtggagcgaa ccgatcaata tcacctccca agtaaaagac ccgtcttggt
    11341 atttcctatt gcaaggcccg ggacgaggca tcacgatgca agacggtacc ttggtcttcc
    11401 cgatccagtt tatcgacgct acccgtgtgc ccaacgccgg cattatgtat agcaaagacc
    11461 gcgggaaaac atggcacctg cataacttag cccgcacgaa taccacagag gcgcaagttg
    11521 ccgaggtaga gccgggcgta ttgatgttaa atatgcgtga taaccggggc ggtagccgtg
    11581 ccgtggccac cacaaaggat ttaggcaaga catggacaga gcatccttcc agccgtagtg
    11641 ccttacagga atccgtttgc atggccagct tgatcaaggt aaatgccaaa gacaacatca
    11701 ccggcaagga ccttctactc ttctccaatc cgaacacgac gaaagggcgt aatcatatca
    11761 cgatcaaggc gagtctggac ggtggactta cttggcccac ggagcatcaa gtcttattag
    11821 acgaggccga ggggtgggga tattcctgtc tttcgatgat cgataaggaa acggtaggaa
    11881 tcttctacga gtcaagcgta gcgcatatga ccttccaagc tatcaaatta caggatctca
    11941 ttcatcaata atctaagtat atgcgatata tactgcattt tgcaattgtt ttaagtttct
    12001 tgtattccgg gcctctgatg gcccggaatc ctgttttatt gcccttgccc caaaaatacg
    12061 tccggacaaa cgcttcgttc catccgaagg aaatcgcagt ttcttccgaa gggaaactcc
    12121 gttccatcct aatggaattc ttggaggagc tgccggtaag cgtccaaccg gacagccgat
    12181 acaagataga ggtttccttg gttgacaaat tggacggaat ccccctcaac tccgaggagg
    12241 cttatcaact aagcgtctct tcccggggga taaccatccg ggcggtatcc gagcaaggag
    12301 cttattgggc gatacaaacc ttgcgccaac tgaccgagcg gcaagggaag cgatattcca
    12361 tccaaggttg cgagatcacc gactggcctg ctttccgcat acgaggattc atgcaagacg
    12421 tagggcggag ctatatctcc atggaagaac tgaaacggga gatcgaggta ctttcccgct
    12481 acaagatgaa cgtatttcat tggcatctca cggagaacca agcttggcgt ctggagagca
    12541 agatctttcc gatgctgaac gacagctgca atatgagccg tatgcccgga aaatattaca
    12601 cgatcgagga ggcaaaggag ctggttcgct tttgtaaaga acataacgta ctactcatcc
    12661 cggaggtaga tatgccggga catagcgccg ctttcatacg ggccttccgt catgatatgc
    12721 agagcaagga gggtatggcg atcttaaaac tattgatgga tgaggtttgc gaggtattcg
    12781 aggaggttcc ttacttacat atcggtacgg acgaggtaaa gtttaccaat ccgaagttcg
    12841 tacccgagat ggtcgcttat atccgtgcga aagggaaaca agtgatctct tggaacccgg
    12901 gatggaagta caaaccgggt gagatcgaca tggagcaaat gtggagttac cggggaaaag
    12961 cgcgaccggg cattcctgcg atcgactccc gtttccatta tatcaaccat tttgatacgt
    13021 tcgccgactt gatcggctta tacaaaagcc gtatttacaa tgaaccgcaa ggaagccatg
    13081 atttggcggg tacgatcctt gccgtatggc acgaccgggt cgtacagccg gaggacaaat
    13141 tgatccggga gaataatttg tatccgaatc tattagcgat cgccgaacgt tcttggttgg
    13201 gcggcggcta tcaatatttc gataagaacg gaacgatgct gcctatcgat cccgataacg
    13261 aggaacataa ggcatttgtc gattttgagc ggcggatgtt atggcataaa gaacatcatt
    13321 tccaaggata cccgttcgcc tacgtcaagc aaaccaacgt gagatggcgt atcaccgacc
    13381 ctttcccgaa tgatggggaa ctgacccgtt ctttccctcc ggaaaagtcg cttcaagcgc
    13441 aatataccta tgaagggaaa aattacggta cgcacgacgc catcggtgcc ggtatctacc
    13501 tgcgccatgt ctggggaccg ctggttcccg gtgcctataa agacccgcaa ccgaaccata
    13561 ccgcttacgc atggacttgg atctattcgc ccaaagcgca agaggtaggt acgtggatcg
    13621 aatttcaaaa ttatagccgt tctgaaatgg atctacctcc aatgcaagga aaatgggatt
    13681 ataaagaaag ccgtatctgg gtaaatgatc aagagataac gccccccgta tggaccgcta
    13741 cccaccggga gaagtccaat gagatcccac tggggaacga gaactgcgta agccgtaaac
    13801 caaccccggt ccatctggaa aaaggctgga acaaggtgtt catgaagctt ccggtcggta
    13861 cgttcaatac ccccgaggtc cgtctggtga aatggatgtt tacgttcgtt tgcgtcaccc
    13921 cggatggaga gaaagcggtg gaaggactgg tttactctcc ggataaacaa cttaaataac
    13981 gtctaattcg gttgaatgaa atgagaaaaa taataggaat cttatccatc ttcctcgctt
    14041 tcgcatttat gagccaagcg caaaagatca aggtggcttg cgtaggtaat agcgtgacct
    14101 acggctacgg aatcaagaac agggaaacaa actgctaccc ggcccaattg caacagatgc
    14161 ttggagatgc ctacgaagtg gagaacttcg ggcatagcgg ggctacttta ttaaacaagg
    14221 gatatcgtcc ttatacccaa caagaggcgt atcaaaaggc actgaggttt gccggggatt
    14281 acgtgatcat ccatctggga ttgaacgata cggaccctcg ggcatggccg aattaccggg
    14341 atgatttcgt ccgggactat ctttccttga tcgaatcctt ccggaaagcc aatccgagat
    14401 gcaaggtatg ggtttgtcgt atgactccga tatctcaccg ccatcctcgt tttaaatccg
    14461 gtacaagaga ctggtactgg atggagcaag cgcttatcga agaaatcgcc cggatagccg
    14521 gcgcgacctt ggtcgatttg caggaaggat tatatgaccg tccggatcta ttgcccgacg
    14581 cattgcatcc aaacgctgaa ggtgccggta tcttggcccg caccgtttat ggggcgctaa
    14641 ccggcgatta cggaggatta cagcttcctg ccatctattc ggaccggatg gtcttgcaac
    14701 gggatcaacc gcttcctata tctggcatcg ccaaccaagg ggagaaagta accgttaccc
    14761 tcgccggaca aaggaaggag accgtagccg gtacgaacgg gaaatggact gtcacgctcg
    14821 atcccttacg ggtaagcggg aaatcctata ccttaacggt ttctaccccc agccgcacgc
    14881 tgaactatcg ggatgtagta gccggggaag tctggctatg ctccggacaa tccaacatgg
    14941 cgttccgggt aaacgagagc gtaaaggaag aacaacagca acaattggat tacgcgaaac
    15001 aacactcgca aatccgttta ttcgacctaa agccccgctg ggagacctac gccgtggaat
    15061 gggacgcttc cgtactggat tcattgaacc gcctgcaata ttaccacgac gcccaatggg
    15121 aagtatgcga cacgcggaat accgcacgct tctcggccat aggatttgcc ttcgggcgta
    15181 tgctggccga tagcttacaa gtacccgtag gattgatatt gaacgctgtt ggcggctcgc
    15241 ctacggaggc atggatcgac cggaaaacac tggaattcga gtttccggat atcttacagg
    15301 attggacgaa gaacgacttt atccaagatt gggtacgtga acgggcggcc ttaaacatca
    15361 agcaagcgtc caacccgctc caacgccatc cgtatgagcc ttgttatctg ttcgaggcgg
    15421 gtatccaacc ccttcatcga tatcccatca aagggattat ttggtaccaa ggagaatcga
    15481 acgcccataa tatgaaagta cacgaacgat tattcccgtt attggtgaac agctggcgcc
    15541 agaattggaa cgcagccctg cctttctact atgtccaact atccagcata gaccgcccga
    15601 gttggacttg gttcagggac agccaacgcc gcctggcgca aaccgtatcg aatacgggta
    15661 tggccgttag tagcgatcgc ggggattctt taaacgttca ccctacccga aaaaaagaga
    15721 ttggcgaacg actggcacat tgggccttga acaagaccta cggacataac gtaatcccat
    15781 ccggcccttt gttccgcagc gcaacgttta ccgataacgc cgcctatatc actttcgatt
    15841 acgcaaaggg cttgacaact tccgatgggg accccatccg tacattcgag atcgccgagc
    15901 aggaaggact ttactatccg gcgcaagccg tggtagagaa cgggaaagta aaggtgtgga
    15961 acgatcaagt gactcacccg aagctggtac gctacggctg gcaacccttc acgagagcga
    16021 atcttataaa cgaggcgggc atgccggcct ctacgttccg ggcaataaaa gaataagcta
    16081 tgcataataa acaacaaatc accggctggt tgttcctcct gctactctgc gtagcgggat
    16141 gcggccagcc tgtatctaaa aaacagaaca ccatgataaa ctggacaaaa ttaccggatc
    16201 taccgggagc agccgatacg gcttcccttg gcgtttccgc cccgttcgcc ggcatccata
    16261 acggcgtatt gatcgttgcc ggaggttgca actttccgga caaacccgtc accgagggag
    16321 gagccaagcg atattatagc gagatattcg tccttcttcc cgaaggctgg aaagagatcg
    16381 accgactgcc tcgtcccgtc gcctacggcg ctacggtttc caccccagaa ggtatcgttt
    16441 gcatcggagg aaacaacagt gattcttcct tggtggaggt ctcccgcatc tcctataacc
    16501 ccacgaaagg agaggtaacg gtttgcgcct taccctcctt accatctcca atggataatc
    16561 tctcggctgc ttttaccgga caggagattt acgtagcagg gggaaatgag aacggacagc
    16621 cctgccatac cttcttacgc ctcaacctag cgaatatcga aaagggatgg gaacaactac
    16681 cggacttccc gggagcagcc cgtgtacagc cggtattagc gaccggagaa agtcccaacg
    16741 gcacacgtat ctatctagcc ggaggcttcc agcccatcct aaacgaagag gaaccgatcg
    16801 tcccgacgga tgtattggta ttcgacccgg caacttttac ctggcaacaa gagaccgttc
    16861 ttcccccgtt taaggacgga gcgaaccgta ccctaacagg aggctgtgcc gtgactttcc
    16921 aaacggataa aatcttattt atgggaggtg tgaactacga ttgtttccta gccgccatcg
    16981 cccgaccgat ccatttagcg aaagcggagg cggcgcaaga ttcagcggcc attacccgcc
    17041 tgcaagcgga agccaaggcc tatatgcacc atccggtaga atggtaccga ttcaatacca
    17101 ccttacttca atacgaccta tccacgaaag catggagcga tctgggcgaa tatgagcagt
    17161 tggcccgtgc cggagcggga gcggttatcc aagatggccg attaaccatc atcaacggag
    17221 aattgaaacc gggtatccgc acgccgcaag tgaatcaagc gaaattataa tagggattta
    17281 gtgggatcgc tggtaagttt gccaacgatc cctgtttact tttcccaccc gattttcagt
    17341 atccggagtc tatttagagc atacgtatcc caaggcaaat cctagacaat aagcacgtaa
    17401 ataatgttct tatataaatc attgaacata aacatcttaa aaagacgatt atactttccg
    17461 caaaacacgt acgtgttttt ggaaaaagtc gtacatgttt ttcggaaaac acgtacatgt
    17521 ttttactgaa tcacacgaca gaaaacaaga gcgtatatgg aaatatacaa taagcctacc
    17581 ttatcatcag atctgaacag tatttcttcc taatctctat ttcatagata ttttggtgca
    17641 gttaccttga ataaatcttg attatccagc ttttagcatt atctttgttc ttagaatata
    17701 ttaacataac cagctaaaca tactaaacac atgaaaacca acatcgcatt attaatagag
    17761 caatccgtta acgttataga ctccttaaat aaaggactac gattaacaca caaagaacaa
    17821 caattttttt gtgaacactt cgaacgtgaa gaaatcaaga aaaacgagtt taccataaga
    17881 atcggtgatt acgaaaaata tctttatttc atagaaagtg gtatcctacg ctattggact
    17941 gcacaagaat atggtgatcc ggacaaagaa gtcacctttt ggttttcttt cccgggtgaa
    18001 ttcgccaact cgtacttttc ccttaaggaa aatcagccat cactcataca tatacaagca
    18061 ttaacagact gtgtaatctg gaaattatcg aagcaagact tagcagattt atatcaaacc
    18121 tccctaaaca taaataagat cgcaagaatt gttctcgaag atgctttatg ccggaaaata
    18181 acgagagaga ccttgctact tggttcctcc gccgaagcta tttatgagga tcttataacc
    18241 aaagaaaaag aactgattaa taatatacca ttaaagtatt tggcatctta cataggagtc
    18301 acccctcaaa gattaagtca aataaggaga aaagttcatt aataagacaa cttatttttc
    18361 gttccacttt tgcgttagag aattataatg aagaatctgt tgtgttaaat cttctttata
    18421 aagcaagaaa cctaagtaaa taattaaaat agtttcattt cataatataa taactgtcaa
    18481 taattttgtc aaattaaaag agaggagttt atatgcaaaa cgaatttgac aacatgacat
    18541 taaaagactt cgaaaataga ggtcaagact tattaaccag agcaaaacag gttgatgatt
    18601 atatatcgta tagacataga atccagcatt taccttatcg tgtcatctct ttgaccggtt
    18661 ctagtgccca catgagagtg atcgatccat attcaaataa agaaaaagaa atgatcagtt
    18721 tcgtttccaa tgattatctg ggcttatcac accatccaga ggttataaaa gcagggattg
    18781 atgcgcttga acaatatgga gccggagcgg gggccagccc tttgattggc gggcacaact
    18841 tcttgcatga gcagttagag caagagatcg ctcatttctt gaaaaatgag tatgcaataa
    18901 cctatacatc cggatacgcc gcaaattgta gcacattact agccatgatg ggtaaagaag
    18961 atatcgcaat catggatatg tttactcatg cgagtgtatt tgacggttgt ttatgtacca
    19021 atacaaagag gttccttcac aacgacatcg attccttggt gcatgtccta aacaacgcaa
    19081 agagcttcaa aaatcgcttt gtaattattg atggcgttta ctcccaagat ggggatatcg
    19141 cctttcttga tcaaatttat accgtatgta aagagcatga cgcattcctc attgttgatg
    19201 acgctcatgg tattggtgta ttaggcaaaa caggccgagg aattattgag gattatgatc
    19261 ttctcgacaa agtagatata attaccggaa cattcagcaa agctttcgga tgcgtgggag
    19321 gttatgccat agccagaaaa gagatcataa ctttactcag atattattca aggcaaaata
    19381 tattttccgc tgccgctaca ccccaaaccg ccgcatccgc aataaaagcc atccaactga
    19441 ttgaccaaga accccaatgg agaaacacac tagccgacaa tatcgaatat tttaaaaccg
    19501 gacttgaaac cttaggtctt gattatggta ataccgaatc agcgatattc cccgtaatgg
    19561 tacgtaatga acactatgtg aaagaagcag ctcgcatatt atttgagcaa ggaatatatg
    19621 taaacccaat cagttatcca gctgtaccgg aaaaattatc ccgtcttcgc ttcagcttaa
    19681 cagctatgca tacgaaggag gagttggata agacatttag tatccttgaa aacattagga
    19741 agaaatacaa actagcacaa atataatcac atttataaat tatataaaga ttagcagctt
    19801 tgttatttac agcaaaaatc aataatttag aaaccttcac ttttacaaag aaaacaatca
    19861 tgataaaaat tatcatttat tcatacggca tctcaagtag ttaatatata ttcatcacta
    19921 taaaatcaat aaatatctac tttaacaaag taaatattta cacaaatata cataaaattc
    19981 aatatatgaa aactagacat ttattaaata tattattatt agcactttat acaagcagct
    20041 gtaataaaga agacacccct ctaatcaaaa cagaaactgt caaaatattt cttttatcag
    20101 aaacaaatag aatccaaaat gaagatattg aaaatcatga atatatacta gcaaaagaag
    20161 aaaatcaagt cgattttcaa gaaataaata tttctgcgat cgagggtttc cattatgaaa
    20221 aagggtatga gtatgaatta ctagttgaaa aaaagaccct cgttaatact aattttgaca
    20281 ataatcagac taaatacaaa ttaattgagt taatctcaaa aaacaaagta gattttaaat
    20341 atttgattat aactaaagaa aatcccttca tactacattc agccggaggc agattcgaaa
    20401 tacctctgca atgtataaaa gaaaaatata ttaacaacaa attatcagaa aaagagcacc
    20461 atcctttaaa aggattaaaa tataagattg gaactaatta tggaggtatt actaatatag
    20521 taaaagaagg gaaagaaatc ggtttttaca aaataattat cgagagatat ggagcataca
    20581 acatgaatgg aattcctgaa tggttttgtg ctttttacac taaaaatgca aatttaaatt
    20641 ttgacctaaa accatctcca atctatgagc aaatatttga gcaaccacaa actaaaggag
    20701 agcagtatct tatccttccg atcataaata tttcaattgg aacatttgat atataaagat
    20761 cctatattaa aatgcaacaa aattaacaca gcaattattc accttataaa tatatattat
    20821 catgaaaaaa gaaatcttta tcttactaac tgcttcactt gtagtttctt catgcgttga
    20881 caatgaagat atatacaaaa atccagacaa tagtaaaaag gatcaagtct taacactatc
    20941 caaatatcct cagaaagtca tagacattga aactggcagt aaagaacact tagctctttt
    21001 aaatgcaacc acacgatcta cctttctcat taaggatagt gtttggccgg ataaaaaagg
    21061 tcattcactc atatatgaaa caaatgaaca cggtacaaca gccaatacaa tgagatacat
    21121 ctatttggga tcattactga aaggtggctc gctagaagaa cagcgttttc aacgcttaac
    21181 aaacgaatta gaccctcttt atatatccta ctcttttcct gctaagattg taggagatat
    21241 aatagagaag cccagcttgc agtcgcaaag aacatcttta agtaaaataa tgaatcaaga
    21301 agggatgaca ggcaaacaga ttgtttcatt tatctatgac atgaatcagt tcacctatta
    21361 taatgaatta aaattagcat ttaattgcaa tatagacgtt gcaagtgttt ttaacatatc
    21421 tacaagtgtt gcgcaaggaa agatcaggaa gaaatgtgga ttagtagcta aatttataca
    21481 aaaaaatttc acagttgatt tagatttacc agcagatgga tgccttttaa aaaacaataa
    21541 tgaattatca aatgttggtc catacgatcc tgtttatata agttcaataa cctatggaag
    21601 aatgggagta atgatgttcg attctagtta tgcatatgat tcattaagag tagcagtaaa
    21661 agcagccttt gatgcaaaaa taataaatgg gaaattagag ctaacaagtg aacaaacgaa
    21721 aataattagt gaagcagact taaaaattgc aatcataagt ggtgatggta gctattctgt
    21781 gaaaacagtg gatggaatta acggatttaa ggaatttatt atagctggag gagaatttag
    21841 taaggatgtt cctggagatc ctatatttta ttcagcaagc tacttaagtg atgattctcc
    21901 attctacgca aaattcagag taaacatacc ttataaataa ttatactatg agaattacat
    21961 caatattttt atttacaatc atcatatttg gaggattatc atgttcaaat gatgatagcc
    22021 ttattcataa taagactaaa ggaatcttag agaaatatcc tgaacccact gtcacaataa
    22081 cagctcataa tcatatacct tttcttgcta aaaatatttt agaagaaaaa gcgattacaa
    22141 aaagtgtaaa tattatctcc gatattgcat gggcaaatgg atttggaaga acaattacag
    22201 cccgatcgga tgaaatggta ataccagaca atatgaatag atacatatac ccgggatcaa
    22261 tattggaagc atctagcatt gcagagacac gatttactcc aatacctgta aaaaacaatc
    22321 cggtccatgt ctctgtctct tttcctgcta aaaaagtagg aggaactata aaagagcctt
    22381 ctttattgaa tatcagacaa tttgtcatgg atctaatgca acaaaataat ataggaaaac
    22441 aaagtgcaac attaagtttt gatgttcaaa aatttgtatc atatgatgaa ttaaaaatga
    22501 cttttggctc taatgaaaat acaggattat tgttttgggg aacttcttct gcgcaatatc
    22561 aaaataaata tagaatcata cgcagctctg gactttgcat aaaatttatt cagaaatatt
    22621 tcacattaga catggatatt cctagtaatg gtctaatttc aggaactata ccaggaggat
    22681 actcacctgt atacgttagc tctattgcct atggaagaat aggtattctc acactagaaa
    22741 caaattacga ttatgaaaaa gctaacaaat tagtgaaaga aacttttaat tcgctattta
    22801 ttaacaagaa taatacactc acaaaggagc aagaagcctt tttcaatagc gcagaaatga
    22861 aagttttcat agcaggagga tcaggggtca caggagttaa aactatagga ggtattaaag
    22921 aattcacaaa ttatattaca gagggaggag agttttcagc atcctcacca ggtaaaccaa
    22981 ttttttgttc ttttgcaaac tatagtgacg attctccata tcgcattaat ttcaaaatag
    23041 atatagacag tgatcctgtt tatgcaagac ttgaatatga tataaccaaa gatgtatcag
    23101 gtggaaatgt taaatcatgg tatactgatg ctaatgttta tttaaggttt tatgcagata
    23161 aagcctgttc aatcaaaacg atagcccaaa actatattgg atttaatata aatcgcctta
    23221 tattacaaca atatgttgga cctaattata gtgttagtaa agcaagagag gtaaaactag
    23281 atcaaaacct cacttttcat aatcaaacaa aaggcataga gtatccaatt gcatatggtc
    23341 atcgcatgac agaaacaata ggcactacat atttagatcg aggaaattgg actaatgacc
    23401 atttttacct aagagcaggt aaattttatc aagtacgacc tcctataaat atgaaatata
    23461 catgtttcat agattatcat aatcaaaatg aatatgactg ttcggatttt gaataattaa
    23521 tattccaaaa taaaataccc ctagagttaa atagacaact ttgggggtat ttctatcata
    23581 ggagcttgaa cctctgtata tattaagatt aatatatgct aaatctactt gttctcatat
    23641 ttatttcata ctctccttct tataatttat acgaacccca tacttcgtgt atactcggtc
    23701 tagccccaac ataccttgtg ggttaggctc gccttgtgct ttgccggaca ggatatcctc
    23761 gctcatcgtg atcatgtctt ttacacgttg aggggtttcc ttgttcattc cgaaataatg
    23821 tccggggtag aggtatttga tatcatattt ctcgatcacc gcactcatct tcttacaagt
    23881 agatattagc gtagagaagt caactcccag caatagatta ccggagccga acgaatcgcc
    23941 gctaaaacca taagcggcat ccttatccac aaaagtggtc gatccgggag tatgcccggg
    24001 agtaaagaca acttcgaggg tacgcccacc caaatctaga atttcgccat ctgtgaggaa
    24061 acagaccttg cctttataat tcggcataaa ttccggtata cctatcgtat cagccggatt
    24121 gatataaatc tccgggaaat aatcgatagc cgagcctgta tggtccggat gcacatgcgt
    24181 ggcgaccagc gtaaccggct tgtccgtgat ggaagccact agcttatcca aatccttgat
    24241 ctttgttcct gcatcaatca agatcgcttt cgtttctccc tcgaccagat acaggctctc
    24301 gttcgccatt aaatgacctg ttccaaacca tgtatgctca tcaatctgat ggaaaatcac
    24361 atcttcattc ctaagcactt ccttctcctc gatacccgcc gtctgtgcct ggcagaacaa
    24421 agcgatcctt gacaggagca acaacatcat taataaacct agttttttca ttatcatatt
    24481 catttttaag atttaaatcg ccgcgatctt ccgaaggctt gcgtcccatt tcggctcggc
    24541 gtagatgaga cggatagctt cttccggcgt gtcggctacc gcccacatct tggcgtgctg
    24601 gggacgcatg aaattctcgt tcatggcgtt cctcaaaagt tccaacaagg gatcatagta
    24661 atgattaata ttgaggatta cgatcggatt gaggtagaga ccgagttgtt tccaagtgat
    24721 gatctccaga agttcctcta atgtaccgca tccaccggga agggcgatca ccgcatccga
    24781 gaggtttgcc atgagctgtt tacgctcgtg catcgtctcg acctcaatca actcggtcaa
    24841 gcctttatga taccaatcct gctccaccat aaaatggggg ataacgcccg ttaccgttcc
    24901 accagccgct aacgcagcgt cggagacagt gcacatcaaa ccgatattcc cggcaccatt
    24961 gactacccgt agttttcgct ctcccaaaag acaccccaat tccttggcgg cgtcaaaata
    25021 aatcggggga atcttcgtgc tggacgcgca atacacgcaa acagacgaga tgttatttat
    25081 cttcttttct tccatatctt tttattcttg atttatatcg tagccaaata aggcgaaatc
    25141 ccccagacaa ggatcatcgg ggaagacttt cgccaatgcg tccgttatct cacgggccgt
    25201 acgaagggta gcggtttttt ggcctgtcaa gcccaagcgc aaggagatct ggtgcacatg
    25261 cgtatccaac gggatgatta attggcgggg atgcacggct gttctccaga taccgagatc
    25321 gacgatacca tccgtacgca ccatccaacg caagaacatc gccagacgct tacaagcgga
    25381 agtcccgtgc aagaccggaa tgccattgag atcagcaaaa agttgttgca accgcaagat
    25441 aggatcttcg caaggaccgg cggcggccat agcgtcttcc atacagtcgt aggtatcgta
    25501 tatatccttt aggcgacaac aaaggagatg cagatcatga taggtataaa aacggtaaaa
    25561 ggtatcccgc ctgcgaaccg ggcggttccg taggggagcg aaagaagtct ctccggtacg
    25621 gataaactcg taaggacttt cgcccatcag ccggtgtagc tcttccgctt tttggagaat
    25681 atgcgccctg cgaccgtaag agatccacgc cgtcaggaaa gccgatatct caatatcccg
    25741 tttctccgta aaccgatggg ggaatcgaac cggatcatcc ttgataaacg attccgtatt
    25801 gtacgttttc gcccattcac gaagtaaaga gatggtcttt gtatccatgt tatttcttct
    25861 ttagaaaata ttgccgctcg ggttccggat aatgctcgat agcgtaacga agcgccgtac
    25921 gaggaagacg agtagcgttg cgttccaaga aatcggtaag cgtctgccgc tcctttttgc
    25981 cgacctcacg cagcatccac ccaaccgcct tatgcatcaa atcgtgttta tgaccgatca
    26041 accgttcgga taactccaag gtatccccaa aatcattccg acggataaat gcccacgtag
    26101 agacgatcga gatccgttgt tcccataaat tctcgctttc cgccaaacgg tagaggaggg
    26161 aacgatcttt gtccaccaaa tattcgccga cgatatcccg acaggtcaaa tctaccaaat
    26221 cccagttatt gcaacgccgc atattcttca gatagaatcg gaagatggct tcccgctctt
    26281 ccggcatcgc tttccgatcc tggaaacgat agaccaaaat cagcaaggca catagacgtg
    26341 cctcatgcca cggactatcc agcaacagct gcagctcatc gaaaggagtc gccttattag
    26401 ccttcgctat gctgcgggtt tgcgggacaa ccactccgag aaactgatcg ccctcgccat
    26461 attgaccggg accagtcttg aaaaagcggc tcaaatgaac cgccttctcg ggtgtaccga
    26521 ccgactgtag ctcggatagg ataaacgccg ccgtcatggc cggagtaccc gtgatacggg
    26581 acggtcgccc tccaagaaac cgatcacgtt gttgcatacc gtgcgtgcca taatgatacg
    26641 ggtttccatc gtctgggtgc cgatatgagg ggttaatacc acgttgtcca tttccaataa
    26701 ctcggggaga ggatagtctc caaactcgaa tacatccaaa ccggcaccat gaatcgtacc
    26761 ttctcgcaag gcttttacca aggcatgctc gtccaccaac gggccacggg ccgtgttgat
    26821 caggatggcg gaaggcttca tctgcttgaa ctcttcctcg ccgaggatat ggtaggtatc
    26881 gggggtataa ggggcgttca aggatacgaa atcggctttc gccagaagct cttccttgga
    26941 gacgtaggta acattcaatt tggtctcgtc ctcgatgcaa agctgacggc gattgtggta
    27001 gatcacatcc atgcccaaag cattcgcccg tttcgccaag gccttgccga tacgtcccat
    27061 accgataatg cccaaggtct gtccggtaac cggcataccg aggttctcca gtacaccgac
    27121 cttcatgtcc ttaccaagcg tacgcagctt acgatcacat tccgtgatac gccgggcggt
    27181 atccagcatc aagcctaaag cgatattggc ggtaggggcc gtgacaggat caggcgtatt
    27241 cgccaccgtc aagcctttct cgagggcgta ggccacatcg atattattat aaccaacggc
    27301 gtagttagcg atcagccgca atttcgacgc atggtcgatc aactctttgt ttaccgggaa
    27361 atcgaacatg gagcagagca catcgtactc cggtatcatc tcgaaaacct cctcatacgt
    27421 aaaatctctt ccttcgggaa aggttacctc gtacttactt tccaactcgg taaatccctc
    27481 gcggaacatg tcgtatgtca ctaatatctt catcttggat ctatttgtta ttcaaaaagc
    27541 aaaaatacaa atcaattggc aattaattcc taaatttgtg accaatatat atttattatg
    27601 gtactaaact atatttggat cgctttcttc ttgatcgctt tcgtcgtggc cgtaggtaaa
    27661 ctggtcattg gtggggatac cgccgttttt accgagatta tcaacgcttc tttcgcttcg
    27721 gccaagacgg gtttcgagat ttcgttagga ttaacgggga tcttgtcgct ttggctgggc
    27781 atcatgaaga tcggtgagaa ggggggggtg atacaagcgt tcgcacgatt ggcggctccc
    27841 gtattcagca agctttttcc ggatatccca agagaccatc ccgtgaccgg ttctat
//
LOCUS       DBMDTB010000046        27881 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_618_length_27881_cov_12.046004, whole genome shotgun sequence.
ACCESSION   DBMDTB010000046 DBMDTB010000000
VERSION     DBMDTB010000046.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 27881)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 27881)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27881
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_618_length_27881_cov_12.046004"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            128..2509
                     /locus_tag="ACZPB4_08965"
     CDS             128..2509
                     /locus_tag="ACZPB4_08965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HIR1098381.1"
                     /translation="MMMKKIRGLFLSFLLLLISISAFSQHKTMISGKVLSTEKTTVDF
                     ATVYLKGTNYGGTTNEEGIYHLQAPAGEYTLVVSAIGYKTVEKPVKLMRGERTKMNVV
                     ISPQATELDEVVVVSNGVTRLKRSAFNAVALDTKALQNSTQNLSEALAQAPGMKIRES
                     GGVGSDMQLMMDGFTGKHIKIFIDGVPQEGVGSSFGLNNIPVNYAERIEVYKGVVPVG
                     FGTDAIGGVINIITKKNRNKWFLDASYSYGSFNTHKSYVNFGQTFRSGLTYEINVFHN
                     YSDNNYYVDTPVKDFTTGAINKKKIEHVKRFHDTYHNEAVIGKIGFVDKKWADRLMFG
                     FTYSHMYKDIQTGVRQEVVFGGKYRKGYSIMPSLDYRKRDFFVRGLDVVLTANYNKNM
                     TNNVDTSSYEYNWRGEMRPLRMPGEQSYQNTRSDNNNWNGTLTANYRIGKAHTFTFNH
                     VINAFRRSNQSLLNEDSEANAIPKETRKNISGLSYRLMPTEHWNLSVFGKYYNQFIAG
                     PVATSSAQDDYIRTTNSVSAMGYGAAGTYFILKSLQAKLSYEKAYRLPTNEEMFGDED
                     LETGDISLRPENSDNVNLNLSYNETFGKHSVYVEGGLIYRNTKDYIQRNISDLSGGKY
                     GATYVNHGRVETKGYNISVRYGFANWVSVGGNFTQMNVRDNVKTVTSGTNQESLTYGA
                     RMPNLPYQFANSDVTFYWRNLWKKGNTLSVTYDNLYMHSFPLYSEAVGSESEFVVPTQ
                     FSHNLTLSYGIQNGRYNISFECRNLTNEKLYDNFSLQKAGRAFYGKVRVYFGN"
     gene            2573..3988
                     /locus_tag="ACZPB4_08970"
     CDS             2573..3988
                     /locus_tag="ACZPB4_08970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4374 domain-containing protein"
                     /protein_id="HIR1098382.1"
                     /translation="MKKNYLMTGLAAALLVGGVFTSCSDDDPVNPDNGGNGNGNGGGS
                     TSEAVSSYVVAASVGDANYLLTADTLGDGSISAKNNGLTTESGTQWIFYKDKYLYRLV
                     YNQGNAGVTSSYVLNTEGKVKERDNTYEIKRFTSYGIYGDYIITSSTGDLGEEYADEN
                     GYLPKGFLLSYLDVAKETFTTNTNTILSENYLGNGEFVTLAGILQANGRIYSAAIPMG
                     LSKYGVKAEGGKYVKYPELVKTESGGSGSGAYEKGELQWTQYPNEAWVAIYANEKFEN
                     PKLIKTDKISYACGRNRSQYYQTIWTADNGDVYVFSPSYAKTMTAEVQKTTLPAGVVR
                     IKANAEGFDPDYYCNLEAQTGGKAFLRCWHITEDYFLLLMYDRPLTESGFAAKELAIY
                     KGEDKSLTYVKGLPSTDVISGFGNTPFSEDGIAYMAVTTTDGSQPAVYRIDPKTATAT
                     KGLTVEAEQISGVGKLTAAQE"
     gene            3998..4828
                     /locus_tag="ACZPB4_08975"
     CDS             3998..4828
                     /locus_tag="ACZPB4_08975"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HIR1098383.1"
                     /translation="MSRTHILLIFLLLPLTLRSQEDICIGKELVLYSTVLQEDRSYWI
                     HLPEHYNMDTKQRYPVVYLLDGDSFFHSLVGIRKTLASGRGKYLPPCIIVGVLNTDRT
                     RDFTPTASAAGRDGKISIDAIPQGGGSEAFSKFLTEELRPAIDSAYRTNGWNMLIGHS
                     YAGLFTLNTFLRHTELFDTYLAVDPSLWWDQGRLVREAEALVAGRDFKGKSLYIGVAS
                     KKRTDRVDIHLDKVSYLLSELLPQAENLRFFSKSFPDENHGTVAVPGIYDGIKQLFGK
                     "
     gene            4825..5928
                     /locus_tag="ACZPB4_08980"
     CDS             4825..5928
                     /locus_tag="ACZPB4_08980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY-associated TM helix domain-containing
                     protein"
                     /protein_id="HIR1098384.1"
                     /translation="MRKFFAKVHLWLSIPFGIIIAIVCLTGAILVFETEILELGYPSR
                     YFVKEVKGEPLSPATLIESARQQLPDSVRINGIRVSSDPRRTYQLILPGKKAAGFIDP
                     YTGEVTGMDDGQGFFLKMMRLHRWLLDEYKRDGSFSWGKSIVGYATLVLAIIIISGIV
                     IWYPRNKKVLRNRLKVKTKAGWFRFFYDLHVSGGFYAALLLLILALTGLTWSFGWYRN
                     AFYSVFGISANPPQAHHAPASSGAKKPAKKKTDYTQWAEVLSALKSHYPDFNSITIQD
                     GSATVSTARYGNTRGSDRYSFDPATGEITEVQLYKDLPKSGKIRGWIYSVHVGSWGGM
                     TTRILTCLVSLLGTIFAITGYYFWIKKQFRKLR"
     gene            complement(6043..6552)
                     /gene="fldA"
                     /locus_tag="ACZPB4_08985"
     CDS             complement(6043..6552)
                     /gene="fldA"
                     /locus_tag="ACZPB4_08985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin FldA"
                     /protein_id="HIR1098385.1"
                     /translation="MKTIGIFYGSSTGTTEGIAKRIAEKLGVEDKDIHDVSNASPADV
                     APYEILLLGCSTWGAGDLQDDWDSYLGKLKKLDLSEKTVALFGCGDSASFSDTFCDAI
                     GTIYSDLRNTGCKFIGAVDASGYSFDSSTACINGMFVGLPLDEMNEDDQTEGRIDQWL
                     ASIRKEGIE"
     gene            complement(6671..8008)
                     /locus_tag="ACZPB4_08990"
     CDS             complement(6671..8008)
                     /locus_tag="ACZPB4_08990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010182336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HIR1098386.1"
                     /translation="MMTDKEVLLLRRKLDLLLRTGKLLMESAADTNRIERNMKRVAAF
                     MGIPEEKLHIDIRWTMIMVNVSDERNSFSKFQKCEKHGINMTTISQVSKLSWRAIEQD
                     YSLDKYEEELEKIVRQPRNYTPYIVAIGAGFACGGFCKLFGGDWIAFLLTSICTFIGF
                     RVRARCVEAGLNAYMGIALAAFICTCLAYASSFLGISGTPYLPLLACALFIVPGVPLI
                     NFVDDMIDNHLLVGITRAANTVMMVAAMTFGIAFALRLLVMNDVSIDHKFSELSMVPH
                     DPYYVYAIAAAISAVGFSMIFNIQRRLLWVVALGGIIAVCIRNFVNFELGYGPVIGSF
                     MGSFVVSLIAVKAVHWFHVPNHVLTIPSVIPMIPGVLMYRSLLGFINLHGVIGEVTNA
                     FSNGINSALIILCISLGVAVPNIFARRYIAKDRQRYLQEELEKRRQRGKFIEW"
     regulatory      complement(8059..8255)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            complement(8522..9022)
                     /gene="nrdG"
                     /locus_tag="ACZPB4_08995"
     CDS             complement(8522..9022)
                     /gene="nrdG"
                     /locus_tag="ACZPB4_08995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HIR1098387.1"
                     /translation="MLSIIDIIEDTTVDGPGFRTAIYAAGCPNKCPGCHNPESWDIHK
                     GKKVRTEEIVEKVLADEFANVTFSGGDPMFQPEGFTEVAKAIKEKSQKTIWCYTGYKF
                     EDLIKNPAQAALLSYIDVLVDGRYKQTLRDESLLFRGSSNQRLIDVQASLNKKEIVKY
                     KYDPFI"
     gene            complement(9035..11242)
                     /locus_tag="ACZPB4_09000"
     CDS             complement(9035..11242)
                     /locus_tag="ACZPB4_09000"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005650708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside triphosphate reductase"
                     /protein_id="HIR1098388.1"
                     /translation="MIQTVVKRDGRIVGFNEEKIVTAIRKAMLHTDKGEDMQLIRQIT
                     DHISFKGEPQMTVEAIQDAVELELMASSRKDVAQKYIAYRNQRSVARKAKTRDMFLEI
                     INIKSNDITRENANMNADTPAGMMMKFSSETTKPFVDDYLLSEEVKEAVSNNYLHIHD
                     KDYYPTKSLTCVQHPLDRILKYGFSAGHGESRPAKRIETASILGCISLETAQNEMHGG
                     QAIPAFDFYLAPYVRNSFIEEVKTLEDLYGQDFSHLYNKPIDDYQTQTLDGLSGDRRV
                     IQHAINRTVSRVHQSMEAFIHNMNTIHSRGGNQVVFSSINYGTDTSAEGRCIIRELLK
                     STYRGVGNGETAIFPIQIWKKKRGVSYLPEDRNYDLYQLACKVTARRFFPNFLNLDAT
                     FNQSEDWNADDPQRYIHEVATMGCRTRVFENRFGPKTSIGRGNISFSTINIVRLAIEC
                     MQVENKEERIALFFAKLDHMLELTARQLHERMEFQKTAYAKQFPLLMSSLWLGSEKLK
                     PNDSIASVINQGTLGIGFIGLAECLVALTGKHHGEDKDSQALGVRIVTYIRDRANQFS
                     EQYQHNYSVLATPAEGLSGKFTGKDRKKFGSLPGITDRDYYTNSNHVPVYYKCSARHK
                     AEVEAPYHDLTRGGHIFYVEMDGDATHNPEAIMRVVDMMDKYNIGYGSVNHNRNRCLD
                     CGYENSTPNLEACPKCGSKHLDKLQRITGYLVGTTDRWNNAKLSELNDRITHN"
     regulatory      11505..11706
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            11756..13939
                     /locus_tag="ACZPB4_09005"
     CDS             11756..13939
                     /locus_tag="ACZPB4_09005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HIR1098389.1"
                     /translation="MKRKCLCAALAVSCAINVSFAQVRLQGKVVDESNEPIPGANIRV
                     SESLNGTTTDASGKFELNLPDGRHRIRVTYLGYEQGVYQTDHSEKDVVIKLKEKYVNI
                     DQVVVTGTGSHRRMSNSPIPVKVLTGKDLKEASVTNFQDAMTKLNPSIVFMENGQGAT
                     MNMNGLTEKYVVILENGKRLAGDDTYSRIDMSNVKRVEILNGAASALYGSDAIAGVIN
                     IITDDSRNKVNVTSNSRYGSKNQFLQSVNADVNVGKFGSYTSYQYQRADGWQLNPYTE
                     SKGELVPTNKQASEGFHRNVINQRFTYDATDRLSFYVRGTFFGRSSDRPMPMDKVNTT
                     NYDMRKETFTYGAGAQYMINKNSYLNADYLSDNHSTYKDFFDGKKSGESDMTKRIHYH
                     NLNVKGIFRLGKYNKLSAGTEFIKELLSSETDNIAGKSMYTTALYAQDEININEHFQA
                     YAGLRYIYHENFKSYATPNVALLYKVGGFNFRGSYAAGFRTPELKELYTESEKKASGA
                     TRLTIGNPDLDPEKSDNFTLSAEYTMRYFSLSVSAFMNNVRSMINYKMLDTAERDAYN
                     TAHGTDYDEIQMRANIDKAKIKGINVTFNSYLGAGFTLNGGYSFMDGKNVYEDEPLDK
                     TVKHSGTVAAMWSHTWNKYKLNVNFNGRIQGERYSTSYGYAPKYSLWNLNTSHTFRAG
                     DFLLEPGVGIENLFDYVDDRPFNYNYATLTPGRTYYVSLLVRFKQ"
     gene            13973..14902
                     /locus_tag="ACZPB4_09010"
     CDS             13973..14902
                     /locus_tag="ACZPB4_09010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016852 - sirohydrochlorin
                     cobaltochelatase activity [Evidence IEA];
                     GO_process: GO:0019251 - anaerobic cobalamin biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sirohydrochlorin cobaltochelatase"
                     /protein_id="HIR1098390.1"
                     /translation="MYRGFLRSMFVCSLLLGLACSLWAKPGREFYASDIWESMEKGDK
                     LAILMVHFGSAYPEARTQVLDVMNKRVKEAFPDVEVRQAYSARSVVSRLRAQGVWVQL
                     PADALVELRDQGFTHVIIQPTIIIEGVEMEAIRKEAEQRKGLFKDLRVGNPLLYDDTD
                     YEAVMKAVSSPSGVTKNGAKLLVAHGTYHASNSAYAKLGYMFQTKGMKDYYTGTREGF
                     PTIEDVGEQMRQAGHKRVQLIPFMFVLIRGTENTVTDFWQKGLRQQGFDVDIYLKPLG
                     ENPAIRSLFIDHIRFAMKYKRATIFDRKKLYTH"
     gene            complement(14976..16073)
                     /locus_tag="ACZPB4_09015"
     CDS             complement(14976..16073)
                     /locus_tag="ACZPB4_09015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016852 - sirohydrochlorin
                     cobaltochelatase activity [Evidence IEA];
                     GO_process: GO:0019251 - anaerobic cobalamin biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sirohydrochlorin cobaltochelatase"
                     /protein_id="HIR1098391.1"
                     /translation="MNKFKYLLLAASLFASSAVFTSCDDGDDDNTANPAEEVVKTSKK
                     HDTAILLCTFGSTFKESIKTYDATLADFQNAFPDADIYLSFTSRTCVNRVEAETGIAR
                     YQPDLWLQALGNAGYKKVAVQSLHIIPGEEYLSLMNTDVKKKFMIESFPSVQVVKSPC
                     LVYDEDDVEAVAKVLYSHYSDKLADNKNILLLMGHGNPDKNYNANTKYTETEEAMQAL
                     AANKNVFVGTVDYGDMLFWPEEGEPNEECVYSKLTKYCEDHNLKPEEITISLAPFMSI
                     AGDHAHNDLWGIEEGDDFSAAAPNADACWRLKLLKMGFKIDTKESHNGSLENCKIIGL
                     GDYDAVRQIWVNHLKALYNDAEAWETGEDYQ"
     gene            complement(16096..18159)
                     /locus_tag="ACZPB4_09020"
     CDS             complement(16096..18159)
                     /locus_tag="ACZPB4_09020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor plug domain-containing
                     protein"
                     /protein_id="HIR1098392.1"
                     /translation="MRLLAFAILVACVQSVCAQSILKDPKELSVLLNEVVVTGTGTEH
                     YLKDAPVQTEVITGKALDSYQGRSMQDILEGLNASITFNPSDMGSGIQMNGLGNDYIL
                     ILINGKRINGDTGGQNDLSIINPANIERIEIVKGAASSLYGSDAIAGVINIITKKNRD
                     KVSLSNTTRVGSYGDILESVQIGFGHKRMNSNTSLSTTHTDGWQNTTQEWDHHEVMDG
                     TVTRTVNRSTNFTLRENLTYKVNDRLSLSADGSFYQKWNYRLHGAFKYYTYDQFYRNF
                     DVAGGAKYTLGGLNFLSVDLTYGNYSYFYNYHHKDVTNFFDPETDLRITRYPGEHILE
                     TSQQRFLGQAKSVFHLGENNILSAGLEYQYDHLKSPRRIENGKASVFTASAYVQDEWN
                     PTDRLNVTVGGRFVVHQEFGATFTPKVSALYKLGDFNIRATYSNGFKAPTLKELHDDY
                     ITQIGGGPWKHYYGNKDLKPQKSNYYSASVEYHASNLQITVTGFYNRIKNMIALTEVP
                     TSAEDRLDEIEASMQHKNLSKARSFGGDISLTYQILSSLAIGGGYSYTDAKAQYTDDP
                     ADPNYMLYTPINGTSFHNANWKLAWNHAWKKYKLDVTLFGRYQSTRFYITDGDGKSYQ
                     LWRLNTRHSVLKKKKWNLDINVGIDNIFDYVDRTPFGRHRGTTSPGRTWYASFIVKFQ
                     NKHKL"
     regulatory      complement(18272..18468)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            complement(18523..19320)
                     /locus_tag="ACZPB4_09025"
     CDS             complement(18523..19320)
                     /locus_tag="ACZPB4_09025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerB family tellurite resistance protein"
                     /protein_id="HIR1098393.1"
                     /translation="MGIGKWIGGVLGFMAFGPLGALAGIILGSFFEEEANMTGQPFGG
                     RTNYDDQYTRRDPYAGERNSFLFSMLVMASYIIRADGKIMHSEMEYVRQFLRRNFGEI
                     AVGQGEEILLKLFDQAKRMEQENSIGFKNTIRECGTQIAYNLSYEERLQLLAFLAEIA
                     KSDGNVCATEINALKEVAIAMGMSEKEVESMLNLQENSLDNAYKVLEIEPTATDDEVR
                     AAYRRMAIKHHPDKVANLGEDIRKAANEKLQKINEAKERIYKARGMK"
     gene            complement(19411..20028)
                     /locus_tag="ACZPB4_09030"
     CDS             complement(19411..20028)
                     /locus_tag="ACZPB4_09030"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HIR1098394.1"
                     /translation="MIKNLIFDFGKVLVNHDLQPLLERHFGDDEVSLIGFHKILSDPK
                     FINMCDRGIIPFDKMIDGAIKRYPEYSDAFTFFKDNYLEEITGEIEGMRVLLKKLKQS
                     GFKLYGLTNWSDTIYRVMEKFDIFRLLDGMVISCEEHFIKPEKEIYLRLRDKYGLKPS
                     ECLFTDDRMVNVLGAKAIGMEAVLFTTPKEYIFEIERICGIKIEQ"
     gene            complement(20021..20614)
                     /locus_tag="ACZPB4_09035"
     CDS             complement(20021..20614)
                     /locus_tag="ACZPB4_09035"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016407 - acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HIR1098395.1"
                     /translation="MKTEYQKCMDEEPFDGSSPEITEMTVRNKRLLHQLRETDYADNE
                     AKQRIYRQMFGSIGKDVYIDIDFRCEYGKNIYFGNKVIVNMNCTFLDNNNIIIGNNVM
                     IAPDVKIYTATHSVHLAERMPERTHPGASICDTIARPVLIEDGVWIGGGSTILPGVTI
                     GKNSVIGAGSVVVKDIPANSIAVGNPCRVIKNIEDND"
     regulatory      21104..21304
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            21391..22902
                     /gene="accC"
                     /locus_tag="ACZPB4_09040"
     CDS             21391..22902
                     /gene="accC"
                     /locus_tag="ACZPB4_09040"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005846494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0004075 - biotin carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HIR1098396.1"
                     /translation="MIRKVLVANRGEIAIRVMRSCKEMGIRTVAVYSETDRTARHVMY
                     ADEAALIGPAASKESYLNIDNLIAAAKRHHADAIHPGYGFLSENADFARCCKQEGLIF
                     IGPSAETMEAMGDKIAARKRMIAAEVPVVPGTEQPLQSAEEALRVCEEIGFPVMLKAS
                     MGGGGKGMRLIHEKGEVVEAYHTARSESLSSFGDDTVYIEKFVEEPHHIEFQILGDNH
                     GNVIHLFDRECSVQRRNQKIVEESPSPFLTADLRKEMGEKAVAAAKAVHYSGAGTIEF
                     LVDKDRHFYFLEMNTRLQVEHPITEEVVGVDLVKEQIRIANNEVLHLRQEDLFQRGHA
                     IECRICAEDTENNFMPSPGIIRQLTEPNGIGVRIDSYVYEGYEIPVYYDPMIGKLIVW
                     ATTRAYAIERMRRVLYEYKITGLKTNLSYLKRIMHNPDFVKGEYNTLFIAKNARMLQR
                     SNGNNEEIENIAMIAAYMDYLMNLEENTSTQLVDTRPISRWREFGLQKGVLRI"
     gene            22915..23439
                     /locus_tag="ACZPB4_09045"
     CDS             22915..23439
                     /locus_tag="ACZPB4_09045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009374 - biotin binding [Evidence IEA];
                     GO_function: GO:0016421 - CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0043687 - post-translational protein
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA carboxylase biotin carboxyl carrier
                     protein subunit"
                     /protein_id="HIR1098397.1"
                     /translation="MEIHIGNRVADVTLVSKEGNKVRLSIDGKPYDVDIVMTENGSCS
                     VLHDGNSFNAEIISGEDHRSYDVNMFYRSYHVDIVDTQKKYLRMRKSAEEKQDDKIVA
                     PMPGKVVKIPVRKGDRLETGDTVVVLEAMKMQSNYKVSSACVVKDILVSEGDSVDNNQ
                     VLMTLDLLKDDSYE"
     gene            23432..24964
                     /locus_tag="ACZPB4_09050"
     CDS             23432..24964
                     /locus_tag="ACZPB4_09050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005829355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA carboxylase subunit beta"
                     /protein_id="HIR1098398.1"
                     /translation="MNNEQLYKDFEALNKEASLGGGLNRIEKQHACGRMTARERIEML
                     LDKGTFNELDKFVVHRCTNFGMDKNKIPGDGMVSGYGKIDGRLVFVYAYDFTAYGGTL
                     SATNAAKIVKVQQLALKNGAPIIALNDSGGARIQEGVNSLAGYASIFYQNTMASGVVP
                     QLSAILGPCAGGACYSPALTDFIFMVKEQSHMFITGPDVVKAVTHEVIDKEELGGAQV
                     HSGKSGVAHFVCDTEEETLMSIRELLSFLPSNNMEDAPVIACADDVRRVEESLQHVIP
                     EDPNVPYDIKDIIEPIVDNHYFFEVMPHFARNIVVGFARLGGRTIGIVGNQPAFLAGV
                     LDIDASDKAARFIRFCDCFNIPLITFEDVPGFLPGCTQEHAGIIRHGAKIVYAYAEAT
                     VPKITLITRKAYGGAYIVMASKPTGADINLAYPMAEIAVMGAEGAVNILYRKANDEEK
                     KQAIREYTEKFSNPYRAAEQGFIDEVIQPRDTRFKLIQALEMAKNKSQSNPPKKHGNI
                     PL"
     regulatory      25122..25322
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            25623..27305
                     /locus_tag="ACZPB4_09055"
     CDS             25623..27305
                     /locus_tag="ACZPB4_09055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative transporter"
                     /protein_id="HIR1098399.1"
                     /translation="MEWINELLWGEGVGHSILLLSVVIALGIQLGKLKLFGISLGITM
                     VLFVGIFLGHFGFTANPSVVHFFREFGLILFVYSVGMQVGPGFFSSFRKGGITLNMLA
                     CGIVFLGVITALIIHYITGIPIPTMVGILSGAVTNTPGLGAAQQAYSDMTGISDETIA
                     LGYAVAYPLGVIGIILSMIFIRYVFRISFAKETEQLEEETDTESGGEAVPISLVVKNP
                     AIFGRSVSELSKLLEHREFVISRILRNDTNRIEIVAGNTVLNGDDKIFVITAEHDVEA
                     IKTFIGQEIQMDRKQWIPAESQFISRRILVTRSEINGKQLGALQLRRLHGINVTRINR
                     AGLELVATPNLVLQIGDRVTVVGSELAVEKVAETLGNSMKRLNEPNLVTIFVGIVLGI
                     IVGSLPISFPGIPQPVKLGLAGGPLIVAILISRFGYRYKLVTYTTQSSNLLLRELGIT
                     LFLACVGLSAGEGFVDTIVNKGGVAWIGYGFIITLLPLLIIGCVGRYFYKLNYFTLMG
                     LIAGSTTDPPALAYSNMAAGNDAPAVGYATVYPLTMFLRVLTAQLMILFFYT"
     regulatory      27415..27619
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            27658..>27881
                     /locus_tag="ACZPB4_09060"
     CDS             27658..>27881
                     /locus_tag="ACZPB4_09060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HIR1098400.1"
                     /translation="MRDLYLIRCLCVFSAWLFSLGVAYGQQIDTTAYHELSGVEVVEK
                     VRPSVTREGTPLQIMDRAGIDRLGVQDLSEA"
BASE COUNT         7312 a         5719 c         6851 g         7999 t
ORIGIN      
        1 cctgaataag gggattgttt ggtatacctc cgtggatttt taatgtgatt ttacccattc
       61 ttaggtattg tggggctgta gtctctgatc gtaactttgc aacgttttaa ataacataat
      121 tgattaaatg atgatgaaga aaatcagagg gcttttcctc tcctttttac tgttgcttat
      181 ttccatctcg gctttttctc aacataaaac aatgatatcg ggtaaagtcc tgtccacgga
      241 aaaaacaacc gtggatttcg ctaccgttta tctaaaaggt acgaattacg gcgggactac
      301 gaatgaggaa ggtatctatc atcttcaagc tcctgcggga gaatatacat tagtagtatc
      361 ggctatcgga tataagacgg tagagaaacc cgtgaaactg atgcgtgggg aacggacgaa
      421 gatgaatgtg gtaatcagcc ctcaagctac ggagttggat gaggtggttg tcgtttctaa
      481 tggcgtgacc cggctcaagc gttctgcgtt caatgccgtg gccctcgata cgaaagcctt
      541 gcaaaattca acccagaact tgagtgaagc cttggctcaa gcgcccggaa tgaagatccg
      601 ggagtccggc ggtgtcggct cggatatgca actgatgatg gatggattta ccggcaagca
      661 tatcaagatc tttatcgatg gggttccgca agaaggtgtc ggcagttctt tcggactgaa
      721 taacattccg gtgaattatg ccgagcgtat agaggtctat aagggtgtgg taccggtggg
      781 tttcggaaca gacgctatcg gaggtgttat caatatcatc accaagaaga accggaacaa
      841 atggtttttg gatgcttctt attcatacgg gtctttcaat acgcataaat cttatgtgaa
      901 cttcggacaa actttccgga gcggactcac gtatgagatc aacgttttcc ataattattc
      961 ggataataat tactatgtgg atactccggt gaaggacttt acgaccggag cgatcaataa
     1021 gaaaaagatc gagcatgtga agcgttttca tgatacgtat cataacgagg ccgttatcgg
     1081 gaaaataggt ttcgtggata agaaatgggc ggatcgtttg atgtttgggt ttacctattc
     1141 acatatgtat aaagatatac agacgggcgt acgccaagaa gtggtgtttg gcggcaaata
     1201 tcggaaggga tactcgatca tgccgtcgtt ggactatcgc aagcgtgatt tcttcgttag
     1261 gggcttggat gtggtattga cggcgaatta taataagaac atgacgaaca atgtagatac
     1321 ctcttcctat gaatataatt ggcgtggcga gatgcgtccg ctccggatgc ccggtgagca
     1381 atcttatcag aacacccggt cggataataa taactggaac ggaaccttaa cagctaacta
     1441 ccgtatcggt aaggcgcata cgttcacgtt caatcacgtg atcaacgcgt tccggcgttc
     1501 gaatcagtct cttttgaacg aggactcgga agcgaacgct atcccgaagg aaacccgtaa
     1561 aaatatcagc ggtctttcgt atcgcttgat gccgacggaa cattggaact tgtctgtgtt
     1621 cggtaaatat tacaaccagt ttatcgcggg gcctgtcgct acttcctcgg ctcaagatga
     1681 ctatatacgt acgaccaatt cggtaagcgc gatgggatat ggggccgcgg gaacttactt
     1741 tatcttgaaa agcttgcaag cgaaattgtc ctatgagaaa gcctatcgcc tgccgaccaa
     1801 tgaggagatg tttggcgatg aggaccttga gaccggcgat atttccttga gaccggagaa
     1861 cagcgataac gtgaatctga atttaagcta caacgagaca ttcggtaagc attccgtata
     1921 tgtggaaggc ggattgatct accgaaatac gaaagattat atccaacgga atatatcgga
     1981 tttgagcggc ggtaaatatg gcgctaccta tgtgaatcat ggtcgtgtag agaccaaggg
     2041 ttacaatatc tcggttcgct acggtttcgc taactgggta agcgtaggag gaaactttac
     2101 gcagatgaat gtaagggata acgtgaagac ggttaccagc gggacgaacc aagagagctt
     2161 gacatatggc gcacgtatgc cgaatcttcc ttatcagttt gccaactcgg atgtgacctt
     2221 ctactggcgt aatttgtgga agaaaggcaa tacgctaagt gtcacttacg ataatttata
     2281 tatgcatagt ttcccgctgt attcggaggc agtaggcagt gaatccgaat ttgtggtacc
     2341 aactcaattc tcgcataacc tgacactctc ttatggtata cagaacgggc gttacaatat
     2401 ctctttcgag tgcaggaatc tcacgaacga gaaattatac gataacttca gcttgcagaa
     2461 ggctggcagg gctttctatg gtaaggtgag ggtttatttc ggtaattaat ttaaagtgtg
     2521 actatctttt atttatcaat aattaattca aaacataata gattaaaaca acatgaagaa
     2581 gaattattta atgacaggtc ttgccgccgc gttattggtt gggggggtat ttacttcttg
     2641 tagtgacgac gatcctgtaa acccggataa cggaggcaac gggaatggaa atggcggagg
     2701 atcgacctcg gaggcggttt cgagctatgt agttgccgct tctgtcggtg acgcgaatta
     2761 cttgttgaca gccgatacgc tgggtgatgg ctctatctcc gctaaaaaca acggactcac
     2821 tacggaaagc ggtacgcaat ggatcttcta taaggataaa tatttgtatc gtttggttta
     2881 caatcaagga aatgccggtg ttacttcttc atacgtactg aatacggaag gcaaggttaa
     2941 ggagcgtgat aatacttacg agatcaagcg gtttacttct tatggtatct acggtgacta
     3001 tatcattaca tcttctaccg gtgatctggg tgaggaatat gcggacgaga atggttatct
     3061 gcctaaaggt ttcttgctct cttatctgga tgtggccaaa gagacgttta cgacaaacac
     3121 gaatacgatc ttgtcggaga attatttggg aaatggcgag tttgttacgt tagcgggtat
     3181 tctccaagcg aacggccgga tctattccgc ggctatcccg atgggattga gtaagtacgg
     3241 cgtgaaagcg gagggaggta aatatgttaa atacccggag ctggtaaaga ctgaatccgg
     3301 aggaagcggt agtggcgctt acgaaaaagg ggaattgcaa tggacgcaat atccgaacga
     3361 ggcttgggtc gctatttatg cgaacgagaa attcgagaac ccgaaactga taaagacgga
     3421 taagatcagt tatgcttgcg gacgtaaccg ttctcaatac taccagacca tttggacggc
     3481 agacaacggc gatgtgtatg tgttctcgcc cagctatgcc aagacgatga ccgcggaggt
     3541 acagaaaacg actttgccgg ccggtgtagt tcgtattaag gctaacgcgg aggggtttga
     3601 tcctgattat tattgtaatt tggaggcaca gacgggtggt aaggcattct tgcgttgttg
     3661 gcatatcacg gaagattatt tcttgttgtt gatgtatgat cgtccgttga ctgaatccgg
     3721 attcgccgcg aaagagttgg ctatttataa aggagaggat aagagtctta cttacgtgaa
     3781 ggggctgcct tccacggatg ttatttccgg atttggcaat actccgttct cggaggatgg
     3841 tatcgcttat atggcggtta cgactaccga tggaagtcaa cctgccgtgt atcgtatcga
     3901 tccgaagaca gctaccgcaa caaaaggtct taccgttgag gcagagcaaa tcagtggtgt
     3961 aggtaaattg actgccgctc aagagtaata agcaagtatg agtcggactc acattctttt
     4021 aatattcctc ctgctcccgc taaccctgcg gagccaggag gatatttgta taggaaagga
     4081 actggttttg tactctaccg tattgcaaga agaccggagt tattggatac acctgccgga
     4141 gcattataat atggatacga aacaacgcta tccggttgtt tacctgctag atggagattc
     4201 tttctttcat tcgctggtag gcataaggaa aacgttggca tccggtagag gtaaatatct
     4261 acctccctgt attattgtcg gggtattaaa tacggatcgg acacgtgatt ttacgcctac
     4321 cgcttcagcc gccggacggg atggtaaaat ctccatagat gcgattccgc aaggaggggg
     4381 aagtgaggct ttcagtaagt ttcttacgga agaacttcgc cctgctatcg atagtgccta
     4441 tcgcacgaac ggctggaata tgcttatcgg tcattcgtat gcggggcttt tcaccttgaa
     4501 tacgtttctt cgtcatacgg aattatttga tacctatcta gcggtcgacc ctagtttgtg
     4561 gtgggatcag gggcggttgg tccgggaggc ggaggctttg gttgcaggcc gggattttaa
     4621 agggaaaagc ctgtatatcg gtgtcgcgtc taaaaaaagg acggaccggg tggacattca
     4681 tcttgacaaa gtgagttatc ttctttcgga gcttttaccg caagcggaga acctgcgttt
     4741 ctttagtaaa tcatttcccg acgagaacca tggaacggta gcggttccgg gtatatatga
     4801 cgggattaaa caattattcg gaaaatgaga aaattctttg cgaaagtaca tttatggcta
     4861 tcgatacctt ttggcattat tattgcgatt gtctgcctga ccggggcgat tctcgtcttt
     4921 gagacagaga tattagaatt aggctaccct tcccgttatt ttgtaaagga agtaaaaggg
     4981 gaacctctct cgcctgccac cttgatagaa tcggcgcgcc aacaattacc cgattcggtt
     5041 cgaataaacg gtattcgggt atcgtctgac ccgagacgaa cttatcaact gatattaccg
     5101 gggaaaaagg ccgcgggttt tattgatccc tacaccgggg aggtgaccgg gatggatgac
     5161 ggacaaggtt ttttcctgaa aatgatgcgt cttcatcgtt ggttacttga tgagtataaa
     5221 cgggatggaa gtttttcttg gggaaaatca atagttggct atgcgacttt ggtcttggcg
     5281 attattatta taagtggaat cgtaatttgg tatccccgta ataaaaaagt attgagaaac
     5341 cggttgaaag taaagaccaa ggctggttgg ttccgtttct tctatgattt acatgtctcc
     5401 gggggattct atgcggcatt gctcctgctt atcttagcgt taaccggatt aacatggtcg
     5461 tttggttggt atcgaaatgc cttttatagt gtcttcggta ttagtgcaaa cccgcctcaa
     5521 gcgcatcatg ctccagcttc ttccggcgcg aagaaacccg cgaagaaaaa gacggattac
     5581 acacaatggg ctgaggtgtt atcggcattg aaaagccatt atccggactt taactcaatc
     5641 acgatccaag atggctccgc tacggtttct acggcccgtt atgggaatac aagaggaagc
     5701 gaccgttact cctttgatcc tgctacgggt gagattacgg aagtccaatt atataaagat
     5761 ctcccaaaat cggggaagat aagaggatgg atttattccg tacacgtcgg ctcgtggggg
     5821 ggaatgacta cccgtatatt gacttgctta gtttccttgt tggggacgat cttcgcgata
     5881 accggctatt atttttggat aaagaaacaa ttcaggaaac tgagatgaaa agaaagaggt
     5941 atgtttgacc cacatacctc ttcataaatc taaaccaatc aagttgaata cgcaaacgtt
     6001 gtaatattaa ggttaaacag ttatgtatgt aaaagtgtgc gtctattcaa ttccttcttt
     6061 ccttatagat gccaaccact ggtcgatccg cccttctgtt tgatcgtctt cattcatttc
     6121 atccaaagga agtccgacga acataccgtt tatgcaggcg gtggaactgt caaatgaata
     6181 tcccgaagca tctacagcgc caatgaattt gcaacctgta tttcgcaggt cggaatagat
     6241 cgtaccgatg gcgtcacaga aagtgtcgct aaaagaggct gagtctccgc aaccgaataa
     6301 tgcgacggtt ttctcactta agtccagctt tttcagtttc cctagataac tatcccaatc
     6361 atcttgcaaa tctccggcgc cccaagtgga acagcccaat aacaagattt cataaggcgc
     6421 tacatcagcg ggagaagcgt tagatacgtc atgaatatct ttgtcttcca cacccagctt
     6481 ctctgcgata cgtttcgcga tcccttccgt cgttcctgta gacgagccgt agaatattcc
     6541 tatagtcttc atttctattt gtttttatag tttgataacg aaagcaaata tccgatatct
     6601 tattagtctc ggcaatacct ataaatatgt attttgacgg tcgggaatac ccacgaatgg
     6661 ccagcttaaa tcaccactcg ataaacttac ctctttgcct gcgtttctcc aattcctctt
     6721 gcagataacg ttggcggtct ttggcgatgt aacgacgggc gaagatattg gggacggcta
     6781 cgcctaaaga gatacaaagg atgatgaggg cggagttaat accattggag aaggcgttcg
     6841 taacctcgcc gatcaccccg tgaaggttga taaaacctaa taacgagcga tacatcaata
     6901 ctcccgggat cattgggata acagaaggga tcgtcaatac atggttcggt acatggaacc
     6961 aatgaaccgc tttcactgcg atcaggctga caacgaaact tcccataaac gagccgatca
     7021 cgggaccata gcccagctcg aagttcacga agttccggat gcatacggcg ataataccgc
     7081 ctaaagcaac cacccataat aaacggcgtt ggatattgaa tatcatagag aaaccaacgg
     7141 cggatatggc agccgctatc gcatatacgt aatacggatc atgcgggacc atgcttagtt
     7201 cgctgaattt atggtcgatc gatacgtcgt tcatcacgag caggcgcaag gcgaaagcga
     7261 taccgaaagt cattgccgct accatcatca ccgtgtttgc ggcacgggta ataccgacca
     7321 gcaagtgatt atcgatcata tcgtctacaa aattaatcaa aggtacgccc ggtacgatga
     7381 atagggcaca agccagtaac gggagatacg gagtaccgga tattcccaga aaagatgagg
     7441 catatgctag acaagtacaa ataaaggcgg caagagcgat ccccatgtag gcgttaaggc
     7501 cagcctctac acaacgggca cgcaccctga aaccgataaa agtacagatc gaggttaaca
     7561 agaacgcgat ccagtctcct ccaaataact tacagaaacc tccacaagcg aatcctgctc
     7621 cgatcgctac gatataaggg gtataattcc gaggttggcg aactatcttt tccaattctt
     7681 cctcatattt atccaaggaa taatcttgct cgatcgcccg ccatgagagc ttactgacct
     7741 gtgatatcgt tgtcatgtta ataccatgtt tctcgcattt ctggaatttg gagaatgagt
     7801 ttcgctcatc gcttacgttc accataatca tggtccatcg gatatcgata tgcaatttct
     7861 cctcgggaat ccccataaag gcggccaccc gcttcatgtt gcgctcgata cggttcgtat
     7921 cggcggcact ttccatcaac aattttcccg tacggagcaa aagatccaat ttgcgccgta
     7981 ataacaatac ttccttgtct gtcatcatct tctttttgtt cttatatatg tgttctctat
     8041 accctaaccc acgaggatat gaatcttaaa tgaatggcag gtcttctgac tgactcccat
     8101 tctaatgcct tcccggctta ctaggccagt ggcgaaagta gtattagaat gttaaaggag
     8161 tttcacagca gcgggactgt accggattct caccggattc ccttttaatc cgtatgcccg
     8221 aacgagcgta cggaaccaat tcggatgcaa aggtatgaaa tcatgctaat atccgtctcg
     8281 cttcagtaag aataattatc cggatactta tatattctct gttggatatg cttctatttt
     8341 agaattcacg acgtggtctg tacggatcac gccgtggatt ttataaatca cgccgtggtt
     8401 tgtacagacc acgttgaaaa ttgaggaata gatgctgatg caattctctt tatatataag
     8461 agaacggatg tttatttctt attccgtaca agattttatg catgtgtgtg ccttaaaagc
     8521 cttaaataaa aggatcgtac ttgtatttta cgatttcctt tttatttaaa gaagcttgta
     8581 cgtcaattaa ccgttggttg ctgcttcccc ggaataaaag gctctcatcc cgaagggttt
     8641 gtttgtagcg gccatctacc aatacgtcga tataggataa tagggcggct tgtgccgggt
     8701 tctttatcag gtcctcgaat ttatatcccg tgtagcacca gatcgtcttt tggctttttt
     8761 ccttgatcgc cttggctacc tcggtgaagc cttccggttg gaacatggga tctcctccac
     8821 tgaaggtgac gttggcgaac tcgtcagcca gcactttctc cacgatctct tccgttctta
     8881 ctttcttccc tttatggatg tcccatgatt cggggttgtg gcaacccggg catttgttcg
     8941 ggcaacccgc cgcatagatg gcggtccgga atcccggacc gtctacggtg gtatcttcga
     9001 tgatatctat gatagacaac atggtaattg aaaattagtt gtgggtgatg cggtcgttca
     9061 gctcggatag cttggcgttg ttccaacggt cggtggttcc taccaagtaa ccggtgatgc
     9121 gttgaagttt gtccaagtgt ttgctgccgc atttcgggca ggcttccaga ttcggggtgg
     9181 agttctcgta gccacaatcc agacaacggt tacgattatg gtttacggaa ccgtatccga
     9241 tattgtattt atccatcata tccacgacac gcatgattgc ttcggggtta tgggtagcgt
     9301 cgccatccat ctctacgtaa aagatatggc cgccacgagt caaatcatga taaggagctt
     9361 ccacttcggc tttatgacgg gcactgcact tataatatac cgggacgtga ttagagttcg
     9421 tataataatc ccgatccgtg atacccggaa gcgatccgaa cttcttacga tcttttcccg
     9481 tgaacttgcc ggacaagcct tcagccggag ttgccagtac gctataattg tgttggtatt
     9541 gctccgagaa ttggttggca cgatcccgga tatacgtaac gatccttacg cctaaggctt
     9601 gcgaatcctt atcttcgcca tgatgcttac cggtaagggc caccaaacat tcggccagtc
     9661 cgataaagcc gatgcccaag gtaccttggt tgataacgga ggcaatcgaa tcgttaggct
     9721 tcaatttttc cgagcctaac cataaggaag acatcaacaa cgggaattgc ttcgcgtaag
     9781 cggttttctg gaactccata cgctcatgca actgacgagc cgtaagttcc agcatatgat
     9841 ccagtttagc gaaaaatagg gcgatacgct cttccttgtt ctccacttgc atgcactcga
     9901 tagccaatcg tacgatattg atcgtcgaga aggagatatt acctcgtccg atagaagtct
     9961 ttggtccgaa acggttctcg aatacacggg tacggcatcc catggtcgct acctcgtgga
    10021 tatagcgctg agggtcgtcc gcattccaat cctcgctttg gttgaaggtc gcgtcgagat
    10081 tcaagaagtt cgggaagaag cgacgggcgg tgaccttgca ggccaattgg taaagatcgt
    10141 agttacggtc ttccggcaga tagcttacgc ctcgtttctt tttccatatc tggatcggga
    10201 agatagcggt ctcgccgtta cctacgcctc tgtaagtgct ttttaataac tcccggatga
    10261 tgcaacgacc ttccgccgag gtgtcggttc cataattgat ggagctgaat accacttggt
    10321 tgccgccacg ggaatggatc gtgttcatat tatggataaa agcctccatc gattggtgta
    10381 cacggcttac cgtgcggttg atggcatgtt gtatgacgcg tctatcaccg cttaatccat
    10441 ccaaggtctg tgtctggtaa tcgtcgatag gcttattata taagtgggag aaatcctgtc
    10501 cgtataaatc ctctaaggtc tttacttcct cgataaagct attacgtacg taaggagcta
    10561 ggtagaagtc gaacgccggt atcgcctgtc cgccatgcat ctcgttttgg gcggtctcta
    10621 gagagataca gccaaggatg cttgcggttt cgattcgttt agccggacgt gattcgccat
    10681 gaccggcgga gaacccgtat tttaggatgc gatccaacgg gtgttgtacg caggtcaagc
    10741 ttttagtcgg ataataatct ttatcatgaa tatggagata gttgttagat acggcttcct
    10801 tgacctcttc gctcaataaa tagtcatcta caaacggctt ggtggtctcg ctggagaatt
    10861 tcatcatcat gccggcgggt gtatcggcgt tcatatttgc gttctcacgg gtgatgtcgt
    10921 tggatttgat attgataatt tccaagaaca tatcccgtgt ttttgccttg cgggctacgc
    10981 ttcgctgatt tcggtaagcg atatatttct gcgctacgtc cttccggcta ctggccatca
    11041 attccagttc cacggcatct tgaatcgcct ctacggtcat ttgaggttct cccttgaatg
    11101 agatatggtc tgtgatctgg cgaatcagtt gcatatcttc tcccttgtct gtatgcaaca
    11161 tggctttacg gatagcggtt actatcttct cctcgttgaa gccaacgata cgcccgtccc
    11221 gtttaacaac tgtctgtatc atgatgttga ttaatttgtg attgattatg tgcgcaaagg
    11281 tatcgtatta ctctgtatga ttttcttttt ggaaaacttt ttgctgatta aattatgtta
    11341 aggtattaat ttgcagtgtg ttgtaaaaag ttttggaaaa ctttgtatct tgcatgattg
    11401 ctttttgttt tcctttttgg cgatgtgatg tgttataagc ttctctttgt aaagctatta
    11461 aagaacataa gccgggatat atttttgttt atataaaata attcatactt ttgcccccgt
    11521 tttggtgatg acgtaaaacc atccggtttc gtcataaaga gggaatccgg tgtgaatccg
    11581 gagcagtgcc cgctactgta agcttttgta aagtagaaaa catttcttat accactgtct
    11641 gtaaaagacg ggaaggtcgt tttctacgag gtaagtcagg aaacctgcca agcgttttta
    11701 ttgctgtttt tctcggggtc aggaaagcgg aaatatacat aataacaaat cgtttatgaa
    11761 aagaaagtgt ttgtgcgcgg ctttagctgt aagttgtgcg ataaacgtat catttgcgca
    11821 ggtacgttta cagggtaagg tcgtggatga aagtaatgaa ccaattccgg gtgcgaatat
    11881 ccgcgtgtcg gaatccttga atggtacaac cacggatgct agcggaaaat ttgagctgaa
    11941 ccttcccgat ggtagacatc gtattcgtgt gacttacctt ggctatgagc aaggcgtgta
    12001 tcaaacggat cactcggaaa aagatgtcgt tattaagctg aaagaaaagt atgtgaatat
    12061 cgatcaagtg gtggtaaccg gtaccggttc gcatcgccgc atgagtaatt cccctattcc
    12121 cgtgaaagtg cttacgggaa aagacttgaa agaggcgagc gtaaccaatt tccaagatgc
    12181 gatgaccaag ctgaatccga gtatcgtatt tatggaaaac ggacaggggg ctacgatgaa
    12241 tatgaacgga ttgacagaga aatacgtggt tatcttggaa aacggtaagc gtttggccgg
    12301 cgatgatacc tattcccgta tcgatatgtc taacgtaaaa cgggtagaga tcttgaacgg
    12361 ggccgcttcc gctttgtatg gtagcgatgc gatcgccggc gttatcaata tcatcacgga
    12421 tgattcccgc aataaggtga acgtgacgag caatagccgt tatggtagca agaaccaatt
    12481 cttgcagtcg gtcaacgcgg acgtgaatgt agggaagttc ggttcatata cttcttatca
    12541 atatcaacgg gccgatggtt ggcaattaaa tccctatacg gagagtaaag gcgagttggt
    12601 tcctaccaat aagcaagctt ccgagggatt tcaccggaac gtgatcaacc aacgtttcac
    12661 gtacgacgct acggatcgtt tgtcttttta tgtgcgtggt actttcttcg gacgttccag
    12721 cgatcgtccg atgccaatgg ataaagtgaa tacgaccaac tatgatatga gaaaagagac
    12781 gttcacttat ggggcgggcg ctcagtacat gattaataag aactcttatt tgaacgctga
    12841 ttatctgtcg gacaatcata gtacgtataa ggatttcttt gatggaaaga aaagcggaga
    12901 gagtgatatg acgaaacgga ttcattacca taacttgaat gtcaagggaa tctttcgttt
    12961 gggcaaatat aataagcttt cggctggtac ggagttcatt aaagagttac tgagtagcga
    13021 gacggataac atagcgggta aaagtatgta cacgaccgcg ctttatgctc aagacgagat
    13081 caatatcaat gagcatttcc aagcgtacgc gggtttgcgc tatatttacc atgagaattt
    13141 taagagttat gcgactccta acgtggcttt gctgtataag gtaggcggtt ttaatttccg
    13201 cggatcgtat gcggctggtt tccgtacacc tgaattgaaa gagctgtata cggaatcgga
    13261 gaagaaagcg tccggagcga ctcgccttac gatcggtaat ccggatctgg acccggagaa
    13321 gagcgacaat ttcacgttga gcgcagaata tacgatgcgg tatttctctt tgtccgtgtc
    13381 cgcttttatg aataacgtac gtagcatgat taactataag atgttggata cggcggaacg
    13441 ggatgcttat aacactgccc atggtacgga ctatgatgag atacagatgc gtgcgaatat
    13501 cgataaagcg aagatcaaag gtattaacgt aaccttcaat agttatctgg gagcgggctt
    13561 taccttgaat ggtggctata gtttcatgga tggaaagaac gtatacgagg atgagccttt
    13621 ggataagacc gttaagcata gtggtacggt agcggctatg tggtctcata cttggaataa
    13681 gtataagctg aacgtgaatt ttaacggacg tatccaaggg gaacgttatt ctacttctta
    13741 tggatacgca ccgaaatatt ccttgtggaa tctcaatacg agccatacgt ttagagccgg
    13801 cgatttcttg ttggaaccgg gagtaggtat cgagaacctt tttgattatg tagatgatcg
    13861 tccctttaat tacaattacg ctacattgac cccgggccgt acctattacg tcagccttct
    13921 ggtccgtttc aagcagtaaa ctgtcacatg tcaactatta actaatataa taatgtatag
    13981 gggattttta cgatccatgt ttgtttgttc actcctgctt gggctcgcct gttcattatg
    14041 ggcgaaaccc gggcgggagt tttacgcttc cgatatctgg gagagcatgg aaaagggaga
    14101 taagttagcg atcttgatgg tacatttcgg gagtgcttac ccggaagctc gtacccaagt
    14161 actcgatgtg atgaacaagc gtgtcaagga ggctttccca gacgtggaag tccggcaggc
    14221 ttatagcgcc cgtagcgtag tgagtcggtt gagggcgcaa ggtgtttggg ttcagttgcc
    14281 ggcggacgcc ttggtggagt tgcgtgatca agggtttacc catgtaatta tccaaccgac
    14341 tatcattata gagggtgtgg agatggaagc gatccgcaaa gaggcggaac agcgaaaagg
    14401 tttgtttaag gatttgcgtg taggtaatcc cttgttatat gatgataccg attatgaggc
    14461 ggtgatgaaa gcggtttcct caccttctgg agtgactaaa aatggggcta agttattggt
    14521 ggcgcacgga acttatcatg ccagtaactc ggcttacgcg aaattggggt atatgttcca
    14581 gaccaaagga atgaaagatt attataccgg aacccgtgag ggtttcccta cgatcgagga
    14641 tgtaggtgag caaatgcgcc aagccggtca taagcgtgtg cagttgattc cttttatgtt
    14701 cgtactgatt cgaggtacgg aaaatacggt tacggatttc tggcagaaag ggctacgtca
    14761 acagggtttc gatgtggata tttatttaaa gcctctaggt gagaatccgg cgatccggtc
    14821 tttatttatc gatcacatcc gtttcgccat gaaatataaa cgggcgacga tttttgatcg
    14881 aaagaaatta tatacacact gaacaattga aaattgagaa ttgaaaatta gtgagtactt
    14941 actgaaccaa ttttcaattc tcaattctca attatttact ggtagtcttc tccggtttcc
    15001 caagcctccg catcattata taatgctttt agatggttca cccagatctg acgaacagcg
    15061 tcgtaatcgc ctaagcctat gatcttacag ttctctaaac ttccgttatg gctttctttc
    15121 gtgtcaatct tgaagcccat cttcaaaagt tttagtctcc agcaagcgtc ggcgttagga
    15181 gcggcagcgc tgaaatcatc accctcctcg ataccccaaa ggtcattatg cgcatggtct
    15241 ccggcaatag acatgaacgg agctaaggag atcgtgatct cttccggttt taagttatga
    15301 tcctcgcagt atttggtaag tttggaatag acacattcct cattaggttc gccttcttcc
    15361 ggccagaaca acatatctcc gtaatcaacg gtacctacga atacattttt gttagcggcc
    15421 aaggcttgca tagcctcttc tgtttccgtg tatttcgtat ttgcgttata gtttttatcc
    15481 gggttaccat gtcccattaa taaaaggatg ttcttgttat cagccaattt atcactgtag
    15541 tggctgtata ggactttcgc tacggcttcc acatcatcct cgtcgtatac caaacaaggg
    15601 ctttttacga cttgaacact cgggaaagac tcgatcatga atttcttctt cacgtccgta
    15661 ttcatcaagc ttaggtattc ctcacccggg atgatgtgta aggactgtac cgctaccttc
    15721 ttgtaaccgg catttcctag agcttgtaac caaaggtccg gttggtaacg tgcgataccg
    15781 gtctctgcct ctacacgatt cacgcaagta cgggaggtaa atgacaaata gatgtccgca
    15841 tcgggaaatg cgttctggaa atcggccaat gttgcgtcgt aagtcttgat agactctttg
    15901 aatgtgctac cgaatgtaca caacaagatc gccgtgtcat gtttcttact tgtctttacg
    15961 acttcttccg ccgggtttgc ggtattgtcg tcgtctccat catcacagga ggtaaaaact
    16021 gcgcttgagg caaatagact cgccgcaagc aaaaggtact taaatttgtt catcgcattt
    16081 aacttttaag attgtttata gtttatgttt attctgaaat ttcacgataa aggaggcgta
    16141 ccaagtccgt ccgggagacg tagttccacg atggcgtccg aacggggtac gatccacata
    16201 atcgaagata ttatcgatac cgacattgat atctaggttc cattttttct ttttcaatac
    16261 gctatgacgg gtattcaatc gccatagctg ataacttttt ccatcaccgt ctgtgatata
    16321 aaagcgggtg gattggtacc ggccgaacaa ggtgacatcc aatttatact ttttccacgc
    16381 atggttccat gctagtttcc aattggcatt atggaatgag gttccgttga tcggggtgta
    16441 gagcatataa ttcgggtcgg ccggatcatc cgtatattgc gctttggcat ccgtatagct
    16501 atagcctcca ccaatagcca aggaagatag gatttgatag gtgagcgata tatctcctcc
    16561 gaaagagcgg gctttggata agtttttgtg ttgcatgctg gcctcgatct catccaatcg
    16621 gtcttcggcg cttgtcggga cctcggtcag ggcgatcatg ttcttgatac ggttgtagaa
    16681 tcctgttacc gtgatctgca ggttcgatgc gtgatattct acgctcgccg aataataatt
    16741 ggacttttgc ggttttaaat ccttattacc ataataatgt ttccacgggc cgccgccgat
    16801 ctgcgtgata taatcatcgt gtaactcctt taaggtagga gccttaaatc catttgagta
    16861 tgtggctcgg atattgaagt cgcctagttt gtacagggcg gagactttag gggtaaacgt
    16921 agccccgaac tcttggtgca cgacgaagcg cccacctacc gtcacattca accgatccgt
    16981 cgggttccat tcgtcttgta cataagcgga agccgtaaat acggaggctt tcccgttctc
    17041 gatacgccgg ggagatttca aatgatcgta ttgatattcg agtccggcgc ttaggatatt
    17101 gttttccccg aggtggaata cgcttttggc ttgtcctagg aaacgttgtt gagaggtttc
    17161 cagaatatgt tctccgggat aacgagtgat acgtaaatcc gtctccggat cgaagaagtt
    17221 cgtaacatct ttatgatggt aattatagaa ataactatag ttaccataag ttaggtctac
    17281 cgaaagaaaa ttcagtcctc ccaatgtgta tttagctcct ccggccacat cgaagttccg
    17341 gtagaattga tcataggtat aatacttgaa tgcgccgtgc agacgataat tccatttctg
    17401 gtaaaaagag ccatcggccg agaggctcag ccggtcgttc actttgtagg ttaagttctc
    17461 ccttagcgta aagttcgtgg atcggtttac ggttcgtgtc acggttccat ccattacctc
    17521 gtgatggtcc cattcttggg tcgtattttg ccagccgtcc gtatgggtcg tactaagtga
    17581 ggtgttggaa ttcattctct tatgcccaaa gccgatttgt acgctttcca atatatctcc
    17641 atatgatccg acacgagtcg tattcgatag gctcacttta tcccggttct ttttcgtgat
    17701 aatattgata acaccggcga tagcgtccga gccatacagg gaagaggcgg caccttttac
    17761 gatctcgata cgttcgatat tggcggggtt gataatactc aagtcgtttt gtccgccggt
    17821 atctccgttg atccgtttgc cattgataag gatcaagatg taatcgttgc ctaatccgtt
    17881 catctggatg ccactaccca tgtcgctcgg attaaaggtg atggaagcgt tcagcccttc
    17941 cagaatatct tgcatactgc gtccttggta actgtcaagg gctttgccag tgattacctc
    18001 tgtttgcaca ggggcgtctt tcagatagtg ttcggtaccc gtaccggtga ccacgacctc
    18061 gttcaatagc acggaaagtt ccttcggatc tttcaatatg ctttgggcgc atacggattg
    18121 tacgcatgcc accagaatag cgaatgctaa aagcctcata tagtgtttta tttatacacg
    18181 aaataaaaca acaagcctct atctggttat gtctcaaaaa ataaattgaa tcgttttttg
    18241 tatgacacat acttctatcc tggaagcttg atgttattgt aagactttag caggtattct
    18301 ggctctcctc tggttagaaa ccttcccatt ccaattctgg aacagtggct tttgaacttc
    18361 taaccaactt aatgaggatt acagctgcag gaacagctcc ggattcacac cggattccct
    18421 ctcaccaaac tatgtgatag cttggttact aaaatcgtgg gcaaaggtag gtctttttaa
    18481 ttaaataata cagacattga gaaaatattt ccattttctt atttacttca tgcctctcgc
    18541 tttatagata cgctccttag cctcattgat cttttggagt ttctcattgg cggccttgcg
    18601 gatatcttca ccaaggttgg ctactttgtc cggatgatgt ttgatagcca tgcggcggta
    18661 agcggcacgc acctcatcgt ccgtagccgt gggttctatc tctaatactt tataggcgtt
    18721 atctagggag ttttcctgaa gatttaacat ggattcaact tccttttcag acattcccat
    18781 cgctatggct acctctttta aagcgttgat ctcggtggcg caaacattac cgtcgctctt
    18841 agcgatctcg gcgaggaacg ccagcagttg cagccgctcc tcataactta ggttgtatgc
    18901 gatctgggtt ccgcattccc ggatggtatt cttgaatcct atgctattct cttgctccat
    18961 gcgtttggct tggtcgaaaa gctttagcaa tatctcttca ccttggccta cggcgatctc
    19021 gccgaagttc cttcggagga attgacggac atattccatc tcgctgtgca tgattttccc
    19081 atcggcacgg atgatatagg aggccattac caacatggag aaaaggaaac tgttacgctc
    19141 cccggcgtat gggtctcttc gtgtatattg atcatcgtaa ttggttctgc caccgaaggg
    19201 ctgtcccgtc atgtttgcct cttcctcaaa gaaagagcct aatataatac cggctaaagc
    19261 gcccagtggt ccgaatgcca taaaccccaa gacaccgcct atccattttc cgatacccat
    19321 attcttcttt gttttatttg tcgttaatca atggtgcgat attcgctatt ctctaaacgc
    19381 atctccggct gttgcaattt ctggtattca tcattgttca attttgatac cgcaaattcg
    19441 ctctatttca aaaatatatt ctttgggtgt tgtgaacaat acagcttcca ttccaatcgc
    19501 ctttgcaccc aacacattca ccattctgtc atccgtaaac aaacattccg acggtttaag
    19561 gccatatttg tcacgaaggc gaagataaat ttccttttct ggcttgatga agtgttcctc
    19621 acatgatatt accataccgt caagtaaccg gaatatgtcg aatttctcca tgacccggta
    19681 gattgtgtcg ctccagttcg tcaacccata tagtttgaat ccagattgct ttaacttttt
    19741 tagaagtaca cgcatacctt caatctctcc tgttatctct tctagataat tatctttgaa
    19801 aaacgtgaag gcatcactat attcaggata cctttttatc gctccgtcaa tcattttatc
    19861 aaacgggatt attccacggt cgcacatgtt tataaatttc ggatctgata gaattttgtg
    19921 aaaaccgatt agtgacactt catcatcccc gaaatgtcgt tcaagcaagg gttgcaaatc
    19981 gtgatttacg aggaccttgc caaaatcaaa aatgaggttt ttaatcatta tcttcgatat
    20041 ttttaattac acggcaagga ttgccgacag ctatggaatt ggcaggaata tctttcacga
    20101 caacactgcc tgctccgatg acagagtttt taccgatggt cacacccgga aggattgtag
    20161 agccgcctcc tatccataca ccatcttcta taaggacagg tcgggcaatt gtgtcgcaga
    20221 tggacgctcc gggatgtgtc ctttccggca tcctttccgc aaggtgaacg gaatgagttg
    20281 cggtatatat tttcacatcg ggggctatca tcacgttgtt accgataatg atattgttat
    20341 tatcgaggaa cgtacagttc atgttcacga tcaccttgtt cccgaaatag atgtttttcc
    20401 catactcgca tcggaagtct atgtcgatgt aaacatcctt gccgatactt ccgaacatct
    20461 gccgatagat gcgctgcttt gcctcattgt cggcataatc cgtttctctg agttggtgta
    20521 gtagcctttt gttacggaca gtcatttccg ttatttcggg cgatgagccg tcgaaaggct
    20581 cctcatccat acatttttga tattcagttt tcatgtgttc aattcatctc attgtagagt
    20641 cttattcttt atttgagcca attattacga caaggtaacg caagcaagaa taggcagctt
    20701 caaattgata tgccttcaag catacgcaaa gttacacaaa atagctgaga acacgaacaa
    20761 acgaaatgta taaaaactgt acttgcctgt tgactctaca aaaagtaagg ctttttcatt
    20821 taacatctca tttaagtgga gcttcttgta aattttagca tgcgctattg ttttcggtgg
    20881 aaggattcag gaaaacacgt acgacctttc cagaaaacac gtacgacttt tttcaaaaac
    20941 atgtatgtgt tttcgcagaa agattatcct gtttttttaa ttttgatttt taatgcttta
    21001 tgcataagct tctcttgtga gcttattgta cggaatttta cttgggatcc gtgtattccg
    21061 tatattccgg cctggctgaa gtggatagtt aaataaaaaa tactatcttt gcccccgaat
    21121 cggttccgca tataccattc gggtatgtgg attaaaaggg aatcgggtgt gaatcccgga
    21181 cagtcccgct gctgtgaagc tccgaagaac atcttgaaac aacactatcg ccactggttc
    21241 tagcgaccgg gaaggcctca agatgggagt cagtcagaag acctgccatt cattaaaggc
    21301 tgtttttgct cgagggatta ggaaagcagt acgaaaagaa taagaatcaa tagttaatga
    21361 tttatggaga atttatgtcc tcgtggcgac atgatccgta aagtgcttgt tgcgaatcga
    21421 ggtgagatcg ctatccgtgt gatgcgctca tgtaaggaga tggggattcg cactgttgcc
    21481 gtatattcgg agaccgatcg taccgctcgg catgtaatgt atgcggatga ggcagccttg
    21541 ataggcccgg cggcttccaa ggaaagttat ttgaatatag acaatctgat cgctgcggcg
    21601 aaacggcacc atgccgatgc gatacatccc ggttatggtt tcttgtcgga gaacgcggac
    21661 ttcgcacgct gttgtaagca agaaggattg atatttatcg gcccgtcagc ggagacgatg
    21721 gaagcgatgg gagataagat cgccgcacgc aaacgcatga tcgccgcaga ggttcctgtg
    21781 gttcccggta cggagcaacc gttgcaaagt gcggaagaag cgcttcgggt ttgcgaagaa
    21841 attggtttcc ctgttatgct gaaagcttct atgggaggtg gaggaaaagg gatgcgcctg
    21901 atacatgaga agggcgaggt tgtcgaggct tatcatacgg ctcgttcaga atcgttgtcc
    21961 tcatttggtg atgatacggt atatatagag aaattcgtag aggagccgca tcatatagaa
    22021 ttccagatat tgggagataa ccatggtaat gtcattcatc tatttgaccg ggaatgttcg
    22081 gttcaacgtc gtaaccagaa aatagtagag gaaagcccgt ctccattcct aacagcggac
    22141 ttacgtaaag aaatggggga aaaggctgtg gctgcggcta aagcggttca ttattccgga
    22201 gcgggaacga tagagttcct tgtagataag gaccgccatt tttatttttt ggaaatgaat
    22261 acccggctac aagtagagca tcctatcacg gaagaagtgg taggggtgga tttggtaaag
    22321 gaacaaatcc gtatcgccaa taatgaggtt ttgcatcttc gtcaagaaga tcttttccaa
    22381 cgaggacatg ccatcgagtg ccggatctgt gcggaggata cggaaaataa tttcatgcct
    22441 tccccgggta ttatccggca attaacggaa ccgaatggta tcggggtacg tatcgatagc
    22501 tatgtatatg aagggtatga gattccggtc tattatgacc ctatgatcgg taaattaatc
    22561 gtatgggcaa cgacacgtgc gtatgcgatc gagcgtatgc gccgggttct atatgaatat
    22621 aaaatcacgg gcttaaagac gaacctcagt tatttgaaac gtatcatgca taatcctgat
    22681 ttcgtgaaag gggaatataa tacattattt atcgctaaga atgcccggat gctacaacgg
    22741 tctaacggta ataacgagga aatcgagaat atcgccatga tcgccgctta tatggattat
    22801 ttgatgaatt tagaggaaaa tacttctacc caattggtgg atacacgtcc tatcagccgt
    22861 tggcgggagt ttggtttaca aaaaggtgtc ttacggattt aacgggtatt ggttatggaa
    22921 atacatatcg gaaatcgtgt ggccgatgtg acattggtca gtaaagaagg gaataaagtc
    22981 cggctttcta tcgacgggaa gccgtatgat gtggatatcg tgatgacgga gaacggcagt
    23041 tgttctgtct tgcacgatgg gaactcattt aacgcggaga tcatctccgg agaagatcat
    23101 cggagttatg acgtgaatat gttctaccgt tcctatcatg tggatatcgt agatacccaa
    23161 aagaaatatt tgcgtatgcg taaaagtgcg gaagagaagc aagatgacaa gattgtcgcc
    23221 ccgatgccgg gtaaagtcgt gaaaatacct gtgcggaaag gagatcgctt ggaaacgggg
    23281 gataccgtgg tcgtacttga ggcgatgaag atgcagagta actataaggt aagctcagca
    23341 tgcgtggtaa aagatatatt ggtatccgag ggagattccg ttgataacaa tcaagtgctt
    23401 atgactttag acctattaaa agatgattca tatgaataac gagcaattat ataaagattt
    23461 tgaggctttg aataaagagg cctcgttggg aggaggattg aatcgcattg agaaacaaca
    23521 tgcttgcggg cgtatgaccg cccgtgaacg aatcgagatg ctgttggata aagggacttt
    23581 caatgagctg gataaattcg tggtgcatcg gtgtacaaac ttcgggatgg ataagaataa
    23641 gattcccggt gatggaatgg taagtggtta tggaaagatc gatggtcgtt tggtatttgt
    23701 ttacgcttat gattttaccg catacggtgg gaccttgagt gccacgaatg ccgctaagat
    23761 cgtgaaagtg caacaattag ccttaaagaa cggagcgccg atcatcgcct tgaatgactc
    23821 ggggggtgcc cggattcaag aaggggtgaa tagcttggct ggttatgctt ctatctttta
    23881 ccaaaatacg atggcctcgg gagtcgttcc ccaattatcg gctattttgg ggccttgtgc
    23941 ggggggcgct tgttattccc cggctttgac cgattttatt tttatggtca aagagcaaag
    24001 tcatatgttt atcacggggc cggatgtcgt aaaggcggtg actcacgagg tgatcgataa
    24061 ggaagagctg ggcggggcgc aggtacatag cggaaaaagc ggggtcgcac attttgtgtg
    24121 tgatacggaa gaggagactt tgatgagtat ccgggaactt ctgagtttcc tgccttctaa
    24181 taatatggaa gacgctccag ttatagcttg tgctgacgat gtgcgtcggg tagaagagtc
    24241 gttgcagcat gtgattccgg aagatcctaa tgtcccttat gacatcaagg atattataga
    24301 gccgatagtg gataatcatt actttttcga ggttatgcct catttcgctc gcaatattgt
    24361 agtgggattc gctcgtttgg gaggccgtac cataggtatc gtagggaacc aacctgcctt
    24421 tttagcggga gtcttggata tcgatgcttc tgataaggcc gcacgtttca ttcgcttctg
    24481 cgattgcttc aatattccat tgatcacgtt cgaggatgtg ccgggcttct tgccgggctg
    24541 tacgcaagaa catgcgggaa ttatacgcca cggggcaaaa attgtctacg cttatgcgga
    24601 ggccacggtt cccaaaatca cgttgattac ccggaaggct tacgggggag cctatatcgt
    24661 aatggcaagt aagcctaccg gtgccgatat aaacttggca tatccgatgg ctgagattgc
    24721 ggtgatgggg gctgaaggtg ccgtgaatat attataccgg aaagccaacg atgaggagaa
    24781 gaaacaagca attcgtgaat acaccgagaa attctcaaat ccttaccggg cagccgagca
    24841 aggatttata gatgaagtca tacaacctag agacacacgt tttaaattga ttcaggcgtt
    24901 ggaaatggcg aaaaataaga gccagagtaa tcctcctaaa aaacatggaa atattccctt
    24961 gtagtaatta ttatttaagg aaaatcaaag cctcttcctg tcgggaggat agcttagagg
    25021 ttaaaagatc ccggttcaat tgttttgtcc cgggattttt ttatttggat aataaaagta
    25081 aacaaaaaag cgaaaagata tgatatatac ggaaaacatg ctatctttgt tcccgaatcg
    25141 gttccgcata taccattcgg gtatgtggat taaaagggaa tcgggtgtaa atcccggaca
    25201 gtcccgctgc tgtgaagctc cgaagaacat cttgaaacaa cactatcgcc actggttcta
    25261 gcgaccggga aggcttcaag atgggagtca gtcagaagac ctgccattca ttaaaggctg
    25321 tttttgctcg agggattagg aaagcagtac gaaaagataa gcaatatctt aaaaggaaca
    25381 aagacgtatg aaaaggatct gttcgcactg tcgtgcgaca tttgaatggc cggtaaccct
    25441 tttgccggaa gaggaaagtt tgtctaaatt atcagcataa gaaatagaaa atatattagt
    25501 aaatgttgtt agaatggatg ccagattaaa ctgggatact aaatgttcaa tatgtgtatc
    25561 tctgccgaag tgattcgcca gaggtacttt tttatcttaa attaatatat acatgaatag
    25621 atatggaatg gattaatgaa ttgttatggg gagaaggggt agggcattct atccttttgt
    25681 tatccgttgt gatcgctctg gggatccagc ttggtaaact gaagctattc ggtatctctt
    25741 tagggattac catggtactg tttgtcggga tctttctcgg gcatttcggt tttacggcga
    25801 atccgtcggt cgttcatttt tttagagagt ttggtttgat cttatttgtt tactcggtag
    25861 gtatgcaagt aggccccgga tttttctctt cgtttcgaaa gggagggatc acgttgaata
    25921 tgcttgcttg cggtattgtt tttctagggg tgattactgc cttgattata cattatatta
    25981 caggcattcc tataccgaca atggtaggta tcttatccgg agcagtgacg aatacaccgg
    26041 gattgggcgc tgctcaacag gcttattcag atatgacggg gatctcggat gaaacgatcg
    26101 ctttaggata tgcggttgcc tatccgttag gtgtgatcgg cattatcttg tcgatgattt
    26161 ttatccgtta tgttttccgt atctcttttg cgaaggagac ggaacaattg gaagaagaga
    26221 cggatacgga atcgggagga gaggctgtac ctatctcttt ggtggtgaag aatccggcga
    26281 tttttggtcg tagcgtaagt gagctatcta aattgttgga acaccgtgaa tttgttattt
    26341 cccgtatttt acgtaacgat acgaatcgga tagagatcgt ggcggggaac acggtattga
    26401 atggagatga taagattttt gttattaccg cagagcatga cgtggaggcg ataaagactt
    26461 ttatcggtca agaaatacag atggatcgta agcaatggat tccggcggaa agccagttta
    26521 tcagccggcg tattttggtt acccggtctg aaatcaacgg taagcaatta ggggctttgc
    26581 agttacgccg tttacatgga attaacgtga ctcggatcaa tcgtgcgggg ctggagttgg
    26641 tagctactcc taatctggtc ttgcaaatag gcgaccgggt gacagtggtc ggtagtgaat
    26701 tggcggtgga gaaagttgcc gagacgctgg gtaattcaat gaaacgcttg aatgaaccta
    26761 atttggtgac tatttttgtt ggtatagttt tgggtattat cgtgggaagt cttcctatta
    26821 gttttccggg tattcctcaa ccggtgaaat taggattagc gggaggtccg ttgatcgttg
    26881 cgatattgat aagccggttc ggttatcgtt ataaattggt tacttatacc acgcaaagtt
    26941 ctaatttact attgagggaa ttaggaatca cgttgtttct cgcctgcgtg ggattgagtg
    27001 cgggtgaagg ttttgtcgat acgatagtca ataagggtgg tgtagcttgg atcggttatg
    27061 gttttataat aacgttattg cctctactga ttatcggttg tgtgggaagg tatttttata
    27121 aactgaatta ttttacgttg atgggattga ttgcgggaag tacgaccgat cctcctgcgt
    27181 tagcctattc caatatggcg gcaggaaatg atgcgccggc ggttggatat gcgacggttt
    27241 atccattgac catgtttttg cgtgtgttga ccgcacagtt aatgatatta ttcttttata
    27301 catagaataa atattttgtt gttagtaatg tttagaaaag tgtaaactcc ctagccttcc
    27361 gccgaagtga ttcgccgggg ggcttttttg ttgctaatca aaaagtaaac atgtatcttt
    27421 gcggccaatc aaggtgtaga tgttatcgat tccgataata atcagtaaaa gggaatccgg
    27481 tgcgagtccg gagctgtacc cgtagctgta agtccttgga gccccggcaa atcttgttgc
    27541 cactgcctat cggataggcg ggaaggtagc cgacagaggg tggacgagcc agaaaacctg
    27601 ccatgatttt gttatgcgac gtttcgggtg aagacgttgg taaatctaaa tgttgctatg
    27661 cgagatttat atcttataag atgcctatgc gtttttagcg catggttatt ctctttgggt
    27721 gtcgcttacg gtcaacagat cgatacgacg gcctatcacg agctttccgg ggtggaagtg
    27781 gtggagaagg tacgtccgtc ggtcacccgt gaaggtacgc ctttgcaaat tatggaccgg
    27841 gcgggaatcg atcgcttggg agtacaagac ctatccgagg c
//
LOCUS       DBMDTB010000047        27726 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_623_length_27726_cov_10.388814, whole genome shotgun sequence.
ACCESSION   DBMDTB010000047 DBMDTB010000000
VERSION     DBMDTB010000047.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 27726)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 27726)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27726
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_623_length_27726_cov_10.388814"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..646)
                     /locus_tag="ACZPB4_09065"
     CDS             complement(<1..646)
                     /locus_tag="ACZPB4_09065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-bladed beta-propeller"
                     /protein_id="HIR1098401.1"
                     /translation="MKRTFTYLLLLVLLACGKQAYNLLISNESIRSNPTGALSDIADE
                     VIAIPLQDSGTHSIKEAKYIRQEGDNLFLISNETLYRFNRKGEFICRITHPDDIRVAG
                     YVVNPANQQLIVLGNTDDIFYYSFNGDLLTRKKLKCDLPENRHMLSISMHNNRIFTTE
                     ECVHGDTAGKTATIEKQIVEYDSSFHKLQSHTIRPVDLERSACPIGCLAPEVAVE"
     gene            complement(744..1508)
                     /gene="yaaA"
                     /locus_tag="ACZPB4_09070"
     CDS             complement(744..1508)
                     /gene="yaaA"
                     /locus_tag="ACZPB4_09070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HIR1098402.1"
                     /translation="MLILLSPAKTMTGTSKIKAPQGTTPRFQQEANEIALHMTQFPID
                     ELSRILKLSPKLAAECYRRYQDFHAEDNQPLQAILAYTGVVFKNISPKDFTEEDFLFS
                     QEHMRFVSGCYGLLRPLDLIKPYRMEFDVKIPELGDGNMYAFWKDRQTNILIHDVRQG
                     DGILLNLASLDIQPSFQWKEVERSVRIITPEFKVWKNGKAETIVIYAKMCRGQMSRYL
                     IKNRISDPEALKAFTWEGFSYKESMSEGDNWVFLQE"
     gene            1660..2292
                     /locus_tag="ACZPB4_09075"
     CDS             1660..2292
                     /locus_tag="ACZPB4_09075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4858 domain-containing protein"
                     /protein_id="HIR1098403.1"
                     /translation="MKMRDVKMRPIFLLIVFILPTMAHAQWTEQDSLRLQEFLSGKEE
                     IRLNPEFQKAIESGTFLRPDQPGTHMLSSPSELPITKDFSEYVQLDTLRRLTNYDSIT
                     PVLFMLLNFKSPSRSLAIQKQAHTIRLPKNQDWKEFKVGKVPMAANVKLTNIYSDVVK
                     DGQRRGGVLATIRVYFDAEDLLETIFWKSARDKKRNRKRENTWKYYNDYP"
     gene            2633..5221
                     /gene="clpB"
                     /locus_tag="ACZPB4_09080"
     CDS             2633..5221
                     /gene="clpB"
                     /locus_tag="ACZPB4_09080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_process: GO:0009408 - response to heat [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HIR1098404.1"
                     /translation="MNLNNFTIKAQEAVQQAVQLVTKNNQQVIEPVHLLKAVIMTGES
                     VTNFIFQKLGVNAQNLNMVLDRQIESYPKVSGGEPYLSSESNAVLQKAIDYSSKMGDQ
                     YVSLEPIILALFTEKSTASQILKDAGVTEKELRQAIEELRKGNKVTSQSAEETYDALG
                     KYAINLNERARSGKLDPVIGRDEEIRRVLQILSRRTKNNPILIGEPGVGKTAIAEGLA
                     HRIVRGDVPENLKSKQIFSLDMGALIAGAKYKGEFEERLKAVVNEVTKSEGEIILFID
                     EIHTLVGAGKGEGAMDAANILKPALARGELRSIGATTLDEYQKYFEKDKALERRFQTV
                     IVDEPSELDTISILRGLKEKYENHHKVRIKDDAIISAVQLSTRYITDRFLPDKAIDLM
                     DEAAARLRLQIDSVPESLDEVSRRIKQLEIEREAIKRENDKSKLEQLNKEIADLKEEE
                     TKQKAQWQSEKEQINKIQQNKIDIENLKFEADKAEREGDYGKVAEIRYGKIKQKEEEI
                     REVQAKLKTMQGAAAMIKEEVDSDDIADVVSRWTGIPVSKMMQSEKDKLLRLESELHT
                     RVIGQEEAINAIADAVRRSRAGLQDPKRPIGSFIFLGTTGVGKTELAKALAEYLFDDE
                     NMMTRIDMSEYQEKFSATRLIGAPPGYVGYDEGGQLTEAIRRKPYSVVLFDEIEKAHP
                     DVFNILLQVLDDGRLTDNKGRVVNFKNTIIIMTSNLGSSLIRENFEKMTPATHDKVVD
                     ETKIQVLELLKKTIRPEFLNRIDDIIMFTPLNEEEIRKIVSLQLNSVKKMLATNGVAL
                     DFTNEAVDFIADKGFDPQFGARPVKRVIQKYVLNELSKALLGGTVDRNRPIVIDRKDD
                     GLEFKN"
     gene            complement(5344..6426)
                     /locus_tag="ACZPB4_09085"
     CDS             complement(5344..6426)
                     /locus_tag="ACZPB4_09085"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1098405.1"
                     /translation="MEPKIQSTTSTRALRSKIGPIKAYLFKASYVISPITPSDLKHSM
                     KGAYKSFLSKTDQAYGHSTSTINPKLYPISTFKQMSLVVVPSFMIESPFEIVAIALIA
                     FLLILLSMREHRHKKDILDTERNMAEEVIRLREKAEESNRLTSAFLANMSHEIRTPLN
                     AIVGFSTLISESEDKEEIKEFAKIIHANNELLLNLINDILDMSKIEAGILDFLYTEVE
                     INELIQTLWRSYRFKIKEGVEFRTELPAESYIIHTERNRLSQVLANFINNACKYTFEG
                     MITIGYEIRKNNIYFFVSDTGKGIAEENISRVFERFAKLDSFTQGTGLGLSICELIIK
                     HLGGEIGVESSVGKGSTFWCTVPTRK"
     gene            6857..7180
                     /locus_tag="ACZPB4_09090"
     CDS             6857..7180
                     /locus_tag="ACZPB4_09090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098406.1"
                     /translation="MSTNNDELLYDEDDSVKFIQNYLPQELKGKFSNDDINYIVDLIY
                     DFYESNGMLDDDGDDEIEIDEEEVVNYVIKNAQKDGVGKFEPEEITFIVQGELEYCDS
                     INMFD"
     gene            7227..7907
                     /locus_tag="ACZPB4_09095"
     CDS             7227..7907
                     /locus_tag="ACZPB4_09095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0015288 - porin activity [Evidence IEA];
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HIR1098407.1"
                     /translation="MRNIKLLSVLLLCMAVVFTSCGTWNNTAKGTAIGVGGGAAVGAG
                     VGALAGNTALGAVIGAAVGGTAGALIGKKMDKQKKELEATLPEDTKIESVNNGEALKV
                     TFDSGILFATNSSTLSDASKSALRNFATSLKANPDTDIRIIGFTDNTGKVDYNQTLSE
                     KRAKSVYDYLMMQGVSTDRMVYEGKGIHDPVASNDTPEGRSLNRRVEIVILANQKMIQ
                     EAQQGTLR"
     gene            8015..9076
                     /locus_tag="ACZPB4_09100"
     CDS             8015..9076
                     /locus_tag="ACZPB4_09100"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HIR1098408.1"
                     /translation="MKKLIYILFVLITIAFVVAAIAGFATGRINPEGKEWISFPGLVL
                     LPVLAANLCLFLMWCVFRSHWCWVPLAALLLNWEFLISMFQIRVFPKEIPIGKEAVKV
                     ITYNVNNFNTDGKKQLPNIADWLRKEDPDIVCLQECPVESALRMDSVAKTLSFLPYYC
                     STRSATKAAGNAIFSKYPILRFESILYPESSNKSLFAVMDIQGDSVRVFNNHFQTTSV
                     NAVKPRLYQAHAEGKQLEETEAAFHMAFQMKKNFVKRATQADYIRQMLDAGEGPVIIC
                     GDFNDTPASYTYRTVKGDLTDGFRDCGSGFGYTFRQLKRIFRIDYIIYSPDFKGVTYD
                     SPNLDYSDHKPVVWLGYVN"
     gene            9185..9835
                     /locus_tag="ACZPB4_09105"
     CDS             9185..9835
                     /locus_tag="ACZPB4_09105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4136 domain-containing protein"
                     /protein_id="HIR1098409.1"
                     /translation="MKKIFPFFLLVLLLASCQKDPDMSKLDNDFLVFTNHDKDAKFES
                     FTTFYIPDSVLVIGTSEKPQFWTANEADDIITTLVNNMESRGFKRTLDKDNADLGLQV
                     SYVQSTQYFADYNDGYNYPYWWWNYPGYWSPGYWGPGWGNWYYPYPVVYSYSVGSLLT
                     ELVDLDTPAASKADAKLPVLWTAYMSGLLSGSDKFDTQLAVRAIEQAFVQSPYVKK"
     gene            9866..10495
                     /locus_tag="ACZPB4_09110"
     CDS             9866..10495
                     /locus_tag="ACZPB4_09110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005647174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane beta-barrel protein"
                     /protein_id="HIR1098410.1"
                     /translation="MKKINKSIKLIALLVVCMAMPTLAGAQVLKNAYFNVDWQINSPF
                     GQDFSKKTSGWGAHAEGGYYVIPNFAIGAFISYHTNNEYVDRQTIPVNSTSVITSDQQ
                     HSIFQLPFGAAFRYNFAPEGQFQPYVGAQLGASYSEMSTYMNVLKVYDRNWGFYVAPE
                     IGMTVYFTPQKQIGVHMAAYYNYATNKGDVLSYHIDGLNNWGIRLGLAF"
     gene            complement(10574..11200)
                     /locus_tag="ACZPB4_09115"
     CDS             complement(10574..11200)
                     /locus_tag="ACZPB4_09115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098411.1"
                     /translation="MKWSIFKLLLLTCVFPLTLHAQEDKYTKRVQRYENAWQRVIPRY
                     TKVQFAGSMAMLSVGTGWNYYRNHWETDMLLGIVPRNANDHANVTFTLKQNYFPWNID
                     LGEKVSFEPLCCGIYVNFLFDRDFWAKQPNKYPPGYYWFSTRIRNHIFIGERITLKLN
                     PNSSWHKSISFFYELSTCDLYIINAIGNSYLKPKDYLSLSFGVKLQIL"
     gene            complement(11181..11987)
                     /locus_tag="ACZPB4_09120"
     CDS             complement(11181..11987)
                     /locus_tag="ACZPB4_09120"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HIR1098412.1"
                     /translation="MLLKKYICLSAATLLTACDLIDYHPYDGRLDSDTSREINPTNIE
                     RIEKVCEGKDTIRFIFMGDTQRSYNETEDFVKYVNQLDSIDFIIHGGDYTEFGLKKEF
                     EWNDDILSKLKVPYVGLIGNHDVIGNGDQVFRKIFGNENFSFVVSDVKFVCLNTNAIE
                     YDYSHPVPDFNFLKNEIADSTRNKRTIVVMHAPPGNEQFDNNVKDVFQLYIKTLPSLM
                     FCLHAHNHCVSAADLFEDGIIYYGCANIAKRSYLLFTLTPDDYMYEVVNF"
     gene            complement(12078..12800)
                     /locus_tag="ACZPB4_09125"
     CDS             complement(12078..12800)
                     /locus_tag="ACZPB4_09125"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HIR1098413.1"
                     /translation="MFNLDKVKGILFDYGGTIDSNGMHWAEVIWMAYEALKVPVSKAV
                     FRDAYVHGERTLGKNPIVKPHHTFLDMLRLKSDLQIQWLKENGHLSTEAITPELPEQL
                     ADWCYEYARKAIDSARPILEQLAERYPLVLVSNFYGNIESVLKDFGLDHLFGAIVESA
                     VVGIRKPDPAIFRLGVDKLGFPADEIVVVGDSYDKDIVPATRIGCQTIWLKSIGWSAY
                     KGNETADIVLSDFTEIKQVFAL"
     gene            complement(12822..13727)
                     /locus_tag="ACZPB4_09130"
     CDS             complement(12822..13727)
                     /locus_tag="ACZPB4_09130"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HIR1098414.1"
                     /translation="MSETKSTPSLESTLKSLDTEEFIDIHFYRPIGYQWALFFNKLGV
                     SPNSITIASIFIGIAAGICFYFQSLAINVIGMLLLIWANSYDSADGQLARMTGQKSAL
                     GRILDGAAGDFWFIAIYAAICLRLTPEWGIWIWLLAATTGFFHSKQAAMADYYRNIHL
                     LFLKGKSGSELSHSPQLKENYKKMSWKHDFIYKLFETFYINYTVGQEAWTPKFQHMMN
                     IIREKYNGQAPEWFRKAFRTKSLPLMKYTNMLSFNTRVIALFVSLFIDMPWLYFVFEL
                     TVLNSMLLYMIKKHEHICEDFSKQL"
     gene            complement(13749..14612)
                     /locus_tag="ACZPB4_09135"
     CDS             complement(13749..14612)
                     /locus_tag="ACZPB4_09135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HIR1098415.1"
                     /translation="MSKLTLAGIRRGNQFSPNHIGNDAAIFALTAQHLRKLGCDVNEY
                     IESDLLLQDPKEKGIFNMVRDWKSIHKLQELEDKNYFVVNSGYGIENCTREKMTRLLL
                     SNHISHPESLILRTDEDPTEALEKAGFFNCWIKRGDFHAIHREDVTYVRNPEEARSIL
                     KEYAIRGIPSAVINEHLVGDLVKFYGVAGTDFFYWFYPSNMHHSKFGLEVINGTAKGI
                     PFDEAQLRLLCHKAAEVLSIHIYGGDCIVSEDGVMRIIDFNDWPSFAPCREEAAPNIA
                     RRIWDLMREHI"
     gene            complement(14629..15327)
                     /locus_tag="ACZPB4_09140"
     CDS             complement(14629..15327)
                     /locus_tag="ACZPB4_09140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HIR1098416.1"
                     /translation="MDYAIIAAGEGSRLAQEGVKWPKPLVRLNGVALIDRLIDVFLKN
                     NATSISIIVNEEMTEVQDYLKALRLPIPFYLLVKSTPSSMHSFYELSHYLDGDKICLT
                     TVDTIFKEEEFSGYIQQFIQEDKLDGLMAVTDFIDDEKPLYVETDNELYIRNFLDQAD
                     GDCRYISGGIYCLRRPALGVLNNAISQGMSRMRNYQRQLIAEGLRLKAYPFSKIIDVD
                     HADDILKAESFLKS"
     gene            15677..15922
                     /locus_tag="ACZPB4_09145"
     CDS             15677..15922
                     /locus_tag="ACZPB4_09145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA];
                     GO_process: GO:0006397 - mRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA recognition motif domain-containing protein"
                     /protein_id="HIR1098417.1"
                     /translation="MNIYIGNLNYRVRESDLQQILEEYGVVDSVKIIVDRDTKRSKGF
                     AFAEMPNAAEAQKAIEELNQAEYEGRQMVVKEAIPRR"
     gene            16046..17284
                     /gene="lpxZ"
                     /locus_tag="ACZPB4_09150"
     CDS             16046..17284
                     /gene="lpxZ"
                     /locus_tag="ACZPB4_09150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LpxZ family protein"
                     /protein_id="HIR1098418.1"
                     /translation="MKNIGVRSLIVGLCLMGLGSWSPSLKAQIADRVYKTDYHIDPEK
                     ARELSVELDNISFFKDNEYTGKFTKGYSLPGLWVQGKAVYYPLRNIKLEAGVHMLIYH
                     GANKYPSMAYQDIAYWKGDQYQKGVHVLPYFRAQMALSDHVNIVLGNIYGASNHNLIE
                     PLYNPELNLTCDPEAGLQLLYDSKAFDLDVWVNWQSFIFREDVHQEAFTVGISSRVKY
                     NDPASRFHFYTPVQGLVQHRGGEIDTIFNNSVQTLMNGAIGVGGVWNTGHRIFKNLNV
                     ELDATGYYQQAGEIWPFDSGYGLYARASADIYDFRVKTSYWTCKDFISMFGSPFFGAA
                     SMIDEGVTFDRPQMIYLGVEYSRQLAKGFSIGVDVDVFHHLSGDMNDADGVKQPMGNA
                     TSFTAGVYMRINPSFLIKKF"
     gene            complement(17384..19990)
                     /gene="xyl3A"
                     /locus_tag="ACZPB4_09155"
     CDS             complement(17384..19990)
                     /gene="xyl3A"
                     /locus_tag="ACZPB4_09155"
                     /EC_number="3.2.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009044 - xylan 1,4-beta-xylosidase
                     activity [Evidence IEA];
                     GO_process: GO:0045493 - xylan catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xylan 1,4-beta-xylosidase"
                     /protein_id="HIR1098419.1"
                     /translation="MKMKQLTVAMITLLLTASCSEKQQDYPFRNPELPLEERIDDLLS
                     RLTPEEKIGQMMNVTPAIERLGIPTYDWWNEALHGVARAGRATVFPQAIAMAATFDDN
                     AVHETFTMVSDEARAKYHQYQKDKEYDRYKGLTFWTPNINIFRDPRWGRGMETYGEDP
                     YLTEKMGVAVTRGLQGDDPNYYKTHACAKHYAVHSGPEWNRHEFNAEATPRDLYETYL
                     PAFEALVKEGDVQEVMCAYNRFEGKPCCSSDKLLIDILRNSWGYDNIILSDCGAIDDF
                     WRKDKNTPRHETHPDAESASADAVLNGTDLECGGSYRALNKALADGKISEKDLDVSLR
                     RLLKGRFELGMFDPDERVPYSKIPYSVVESPEHIAKALDMARKSIVLLKNKNNMLPLD
                     KNIKKIAVVGPNAADSTMLWANYNGFPSKTVTIVEGIRNKVPNAEVIYELGCNHTADF
                     VVTDLGSHVSSTAGQGFASEFFNNTEFEGTPAYKGLAKELHYTTGGNTQFAPNVNLTN
                     FTARFTGEFESPIDGPVEFKLSGNDAFRLYIDTAKVAEVWENEYGAEKLYTLNAKKGE
                     KYPIKIEYMQRTGSADLNFTVGVRTPVDFQATASKVKDADVIVFVGGISPRLEGEEMP
                     VDAEGFRKGDRTNIEIPAVQKEMVKALVATGKPVVYVVCTGSALALNWENDHVNAILN
                     AWYGGQEGGTAVADVLFGDYNPAGRLPITFYKSVDQLPDFQDYSMKGRTYRYMTQTPL
                     YPFGYGLSYTTFDYKNAKLSKDKIASNESVTLSFDIANTGKMDGDEVAQIYIKNPNDP
                     AGPLKAMKAFKRVNVKAGSEQPVSIQLEPKAFQSFNDNTQTMEVRPGKYQILYGGSSD
                     DKTLKKIDLVIE"
     gene            20196..21026
                     /locus_tag="ACZPB4_09160"
     CDS             20196..21026
                     /locus_tag="ACZPB4_09160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5032 domain-containing protein"
                     /protein_id="HIR1098420.1"
                     /translation="MKKYLFLLLIGAASLTACGDDDDPVVPELNKLTKVSCYKDGASS
                     PLFTADINYMNDGKISSISFHGDKEFRLFSSDNKYLMIDISTGDELGEYILSGNVITA
                     KNVLRKNSYASNEVYVSDEYKYGYSGSNLVLTSWVARWPKEDGQGYESEDYREYDKFY
                     WENGNVVTFSRNQDRMEYEYSTVERPENYPLRVIGSFAPVDFEAVTPLNLLYGVQNRN
                     LPIRAYTYTIPNQSEVKAEYKYTYTTVGDYIMCMTIDENDGGTASSYKYTFEYNFAVK
                     "
     gene            21153..21908
                     /locus_tag="ACZPB4_09165"
     CDS             21153..21908
                     /locus_tag="ACZPB4_09165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NigD-like protein"
                     /protein_id="HIR1098421.1"
                     /translation="MNGFFNFRKLVVGVMAATCFMGFQSCLDDDDDYPYSKVLPNALV
                     TVKPVDDGSYFLQLDDSTTLLPVNMTSSPFGQKEVRALVNFDETNESSGIYSKAVNIN
                     WIDSILTKPIAPDLGVTSNDSIYGSDPVEIVNDWVTIAEDGYLTLRFRTIWGDRNKAH
                     FVNLLTGKDPENPYEVEFRHNAYGDVYGAYADGLVAFKLDSLPDTNGKTVKLKLKWKS
                     FDGDKSVEFNYCSRKSTPAKASIAAERSALNLK"
     gene            complement(22051..22133)
                     /locus_tag="ACZPB4_09170"
     tRNA            complement(22051..22133)
                     /locus_tag="ACZPB4_09170"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(22097..22099),aa:Tyr,seq:gta)
     gene            complement(22153..22226)
                     /locus_tag="ACZPB4_09175"
     tRNA            complement(22153..22226)
                     /locus_tag="ACZPB4_09175"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(22190..22192),aa:Thr,seq:tgt)
     gene            complement(22375..23022)
                     /locus_tag="ACZPB4_09180"
     CDS             complement(22375..23022)
                     /locus_tag="ACZPB4_09180"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006801 - superoxide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HIR1098422.1"
                     /translation="MLTLCLSLLLMITNSQITDKKEEVMKFELIQLPYANDGLEPVIS
                     KQTIDFHYGKHLLNYVNTLNKLIEGTKFENAPLEQIVRESDGAIFNNAGQVLNHNLYF
                     TQFSPNGGGEPTGKLAEAIKSTWGSFENFQKEFVAAGTGLFGSGWVWLAKDKDGKLSI
                     TKEPNGSNPVVKGLTPIMGFDVWEHSYYLDYQNRRADHLNALWGIIDWETVGKRY"
     gene            23219..23758
                     /locus_tag="ACZPB4_09185"
     CDS             23219..23758
                     /locus_tag="ACZPB4_09185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvoyl-dependent arginine decarboxylase"
                     /protein_id="HIR1098423.1"
                     /translation="MVKKVGNLIPNTFFITKGSGESDLEKHAGSYHMALYDAGISDFN
                     IMTYSSVIPATAHLATMDELDLPPFGSEMKTIMAVSHGYQDEFVSAGVVYAWMYKDEN
                     FDEKVGGLVCEVSGRYRIEELESRLIRVINDLHQKTYGKYYLGELNFITEGITIEKRY
                     GTALAALCFVDFLQPEIEE"
     gene            23865..24341
                     /locus_tag="ACZPB4_09190"
     CDS             23865..24341
                     /locus_tag="ACZPB4_09190"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0047617 - fatty acyl-CoA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HIR1098424.1"
                     /translation="MKKIINPWEGLDGYMCFGCAPNNPLGLHMEFFEDGDDIVAFWKP
                     QGTYQGWLRTLHGGIQTTLMDELAGWVVLRKLQTSGVTSRLDAKFMKSISTDEPQLTI
                     RGRMTDRKRNAIFIETEIYNSANELCTRAEMVYFITPQERAMEEFGFCGCKTEDEH"
     gene            24370..25215
                     /gene="nfo"
                     /locus_tag="ACZPB4_09195"
     CDS             24370..25215
                     /gene="nfo"
                     /locus_tag="ACZPB4_09195"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HIR1098425.1"
                     /translation="MKYVGAHVSAVGGVENAPVNAHEIGAKAFALFTRNQRQWKSQPL
                     KADSIHLFKERCEAYGYDPGCILPHDSYLINLGNPDAEGLQKSRDAFLDEMTRCEQLG
                     LKMLNFHPGSHLGKMEVDTCLSRIAESINITLAQTSGVCAVIENTAGQGSNLGYTFEQ
                     IAYIINEVEDKSRVGVCLDTAHTLAAGYDIKTPEGFSETFRHFDEVVGFSYLRGMHLN
                     DSKKELGSRVDRHESIGKGLMGLDTFRMIMADPRFDNMPLILETPDEALWPEEIQLLY
                     KQLKS"
     gene            25220..26629
                     /gene="nhaD"
                     /locus_tag="ACZPB4_09200"
     CDS             25220..26629
                     /gene="nhaD"
                     /locus_tag="ACZPB4_09200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005642618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter NhaD"
                     /protein_id="HIR1098426.1"
                     /translation="MFILMPVIFVLGILAIALEDKIKINKAAIALFMAISMWMILMFD
                     AYNIFVERSSTIFQEFLTQNPEMASLPPHEQFINFISNRAIVYHLGNVSETLFFVMCS
                     MLIVDIVDKHGGFRAVTGYIRTPNKRKLLWYISFATFFFSALLDNLAAAIVIMAVLRK
                     LVPDRTDRLKYACMVIIAANAGGSWSPIGDVTTILLWVGKNISAMHQISHVFIPALVN
                     MLVPLTIAHFWLFKKGSTLRVLSEEEQGDEYIPEIPNRSRRMIFVIGVLSLALVPVFQ
                     MVTNLPPFLGVLLGLVILWFYTDLMYSKLHMHESQKLRISQLLPNIDLATIFFFLGIL
                     MAVGALETSGQLGIMSAFLDKHVHEPYLISFVIGALSSCVDNVALVAATMGMYPIVEQ
                     VADLSPYAQFFVSDGGFWTFLAYCAVTGGSILIIGSATGVTVMGLEKIDFMYYTKRFS
                     ILALIGYCCGAGVYMLLFA"
     gene            26642..>27726
                     /locus_tag="ACZPB4_09205"
     CDS             26642..>27726
                     /locus_tag="ACZPB4_09205"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016805 - dipeptidase activity [Evidence
                     IEA];
                     GO_function: GO:0070004 - cysteine-type exopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C69 family dipeptidase"
                     /protein_id="HIR1098427.1"
                     /translation="MKKSWILLTACAALLSGVEAIACTGLLVGKKASTDGSVMISYAA
                     DSHSLYGEMYRWPAATWPKGAMLEVKEWDTGKPLGKIAQVEKTYSVVGNMNEHQVAIT
                     ESTFGGRHELVDTTGIMDYGSLIYIALQRSKSAREAIKVMTDLVKEYGYYSSGETFSI
                     ADKNEAWVMEMIGKGPGNKGAVWVAIRIPDDCISAHANQSRIQQIPFDDKENCMYSPD
                     VVSFAREKGYFKGKDADFSFAKAYCPYDFSALRGCEARVWSFFRKYDTTMDQYMDFIK
                     GDPSKEPMPLYVKPNRKLSVQDVQNGMRDHYEGTDLDMTKDAGAGSYKVPYRWRPMTF
                     EVDGQEYTNERAIATQQTGFVIVPQMR"
BASE COUNT         7208 a         5734 c         6857 g         7927 t
ORIGIN      
        1 gctccacggc tacttccggg gcgagacaac cgatcgggca tgcggaacgt tccagatcga
       61 ccggacggat cgtatgagat tgtaatttat ggaaagagga atcgtattca acgatctgtt
      121 tctcaatcgt ggcggttttc cctgccgtat ccccatgaac acattcctcg gtggtaaata
      181 tccggttatt gtgcatggat atggatagca tatgcctatt ctccggaagg tcgcatttca
      241 gtttcttgcg ggtaaggaga tcaccattga atgagtaata gaaaatatcg tccgtgtttc
      301 caagtacgat cagctgctgg ttggccgggt tcactacata ccccgctacc cgtatgtcat
      361 ccggatgggt gatgcgacag ataaattctc ccttgcgatt gaaacggtaa agcgtctcat
      421 tgctgataag gaataggttg tctccctctt gacggatata cttggcctcc ttgatcgaat
      481 gcgtccctga gtcctgtaat ggaatggcga ttacctcatc cgcgatgtca gacaaggctc
      541 cggtagggtt gctccggatc gattcattcg agattaacag gttataggct tgctttccgc
      601 aagccaatag aacaagtagt aataaatatg taaaggttct tttcatatca ccgctaaatt
      661 aaagaaggat aaaccttttt atgattttta cgaattgttc ttataaaacg tagatcatct
      721 gattttattg gataagccta gaattattct tgtagaaata cccaattatc cccctcggac
      781 atggattctt tataggaaaa gccttcccat gtgaatgctt ttaatgcctc cgggtcagaa
      841 atccggttct ttatgagata gcggctcatt tgtccccggc acatcttggc atagatcacg
      901 atcgtctccg ctttgccgtt cttccagacc ttgaactcgg gcgtgatgat ccggacggat
      961 cgctccacct ccttccactg gaaagagggt tggatatcca agctggctag attcagtagg
     1021 attccgtctc cctgtcggac gtcatggatt aatatatttg tttgcctgtc cttccagaag
     1081 gcgtacatat tcccgtcgcc tagttccggg atttttacgt cgaactccat ccggtaaggc
     1141 ttgataaggt ctaatgggcg aagtaacccg tagcatcccg atacgaaacg catatgttct
     1201 tgcgagaaaa gaaaatcctc ctccgtgaag tctttcgggc tgatattctt gaatacgaca
     1261 ccggtatagg cgagtatcgc ttgcaagggc tggttgtctt ccgcatgaaa atcttggtat
     1321 ctgcggtaac attccgccgc cagtttcggg ctgagcttga ggatacgact taattcgtca
     1381 atgggaaatt gggtcatatg cagggcgatc tcgttcgcct cttgctggaa acgtggagtc
     1441 gtgccttgcg gcgcttttat cttggatgtc ccggtcattg tcttagccgg agataataat
     1501 atcaacatat ctatattgga tttggattga tcgcataaag ataatccata ttaagattca
     1561 aatagggtat aagcatccca ataaatctta aagtatctcg actcgaatgg gggtttcgat
     1621 agaggaatga gtcttggtga taaaaatgta atgaggatta tgaagatgag agacgtgaag
     1681 atgcgaccta tattcctttt gatagtattc atcctaccta cgatggccca tgcgcagtgg
     1741 acggaacagg attctttgcg cctgcaagaa tttttatccg gcaaggagga gatacgtttg
     1801 aatcctgagt ttcagaaggc gatagaaagc gggacttttc tacgacccga tcaaccggga
     1861 acccatatgt tatcctcgcc aagtgagttg ccgattacga aagacttctc ggaatatgta
     1921 cagttagata ctttacgtag gttgactaat tatgattcga ttaccccagt cctattcatg
     1981 ctgctgaatt ttaagtcacc ttcccgttca ttggccatac agaagcaagc gcacacgatt
     2041 aggctcccta agaatcagga ttggaaagag tttaaggtag gtaaggttcc tatggctgcc
     2101 aacgtaaaac tgactaatat atactcggat gtcgtgaagg atggccagcg aaggggaggg
     2161 gtactcgcta ccataagagt ctatttcgac gcagaggatt tactagagac tattttctgg
     2221 aaaagtgccc gtgacaagaa gagaaacagg aaacgggaga atacgtggaa gtattataat
     2281 gactatccgt aaattattgg atttatagga tataaccact cgaaaaaaac acgtacgtga
     2341 atttcaaaaa acatgtacgt gtttccggaa aaactcgtac gtgttttttt gagaacattg
     2401 actgttttta cctagatact gtgtgtttac tatcaaaacc tttttctctc tcttttgttc
     2461 tttctgaaaa gatacgtcct aatgacatcc gaaatggacg gtttgacggg gagttctcta
     2521 ttctgtttta taatattaag acaaaatgtc atattttcgt tttggtattt cttttgtaag
     2581 gatataagtg taaaataaat tagaaaagaa tataagaaag gagcttaaat atatgaattt
     2641 aaacaatttt acaatcaagg cgcaggaggc tgttcaacaa gctgtacagt tggttaccaa
     2701 aaataatcaa caggttatcg aaccggttca cttgttgaaa gctgtcatta tgacgggtga
     2761 gagtgttact aattttatct ttcagaaatt aggggtaaac gctcaaaacc tgaatatggt
     2821 actggatcgc caaatcgaat cttatcctaa ggtttcggga ggcgaaccct atctctctag
     2881 cgagtcgaac gctgtcttac agaaggcgat cgattattcc tctaagatgg gggatcaata
     2941 tgtatcgttg gagccgatca tcttggcgtt gttcacggaa aagagcaccg cttcacagat
     3001 attgaaagac gccggcgtga cagagaaaga gttacgtcaa gcgatcgagg aattgcgtaa
     3061 aggaaataag gtgacaagcc aatccgccga ggagacgtac gatgccttag gaaaatacgc
     3121 catcaatttg aacgagcgtg cccgtagcgg taaactggac cccgtgatcg gacgtgacga
     3181 ggagatccgc cgtgtcttgc agatcttgag ccgccgtacg aagaacaatc cgatcttgat
     3241 cggtgagccg ggtgtaggta agactgctat cgctgagggg ttggcccatc gtatcgttcg
     3301 gggtgacgtt cccgaaaact tgaagtctaa acagatcttc tcgttggata tgggcgcgtt
     3361 gatcgccgga gctaaatata aaggcgagtt cgaggaacgt ttgaaagcgg tggtgaacga
     3421 ggttacgaaa tccgagggtg agatcatcct ctttatcgat gagatccata ccttggtagg
     3481 agccggtaaa ggcgaaggcg ccatggatgc agctaacatc ttgaaaccgg ccttggctcg
     3541 tggtgagcta cgttcgatcg gtgccacgac gttggatgag tatcagaagt attttgagaa
     3601 ggataaggcg cttgagcgtc ggttccagac cgttatcgta gacgagccga gtgagttgga
     3661 tacgatctcc atccttcgtg gtctgaagga gaaatacgag aatcaccata aggtacgtat
     3721 caaggatgat gcgattatct ccgccgtgca gttgtctacc cgttatatca cggatcgttt
     3781 cttgccggat aaggcgatcg atttgatgga tgaggccgcc gcccgtctgc gtttgcagat
     3841 cgattccgta ccggagtcgt tggatgaggt ttcccggcgt atcaaacagt tggagatcga
     3901 gcgtgaggcg atcaagcgtg agaacgacaa gtcgaaatta gagcaactga acaaggagat
     3961 cgccgacttg aaggaggagg agaccaagca aaaggctcag tggcagagcg agaaggagca
     4021 gatcaataag atccagcaaa ataagatcga tatcgagaac ctaaagtttg aggctgacaa
     4081 ggcggagcgt gagggtgatt acggcaaggt cgctgagatc cgttacggta agatcaagca
     4141 aaaggaagag gagatcaggg aggtacaggc taagttgaag acgatgcaag gtgccgcagc
     4201 tatgatcaag gaggaagtgg atagcgacga tatcgccgat gtggtatccc gttggactgg
     4261 aattccagtc agcaagatga tgcagagcga gaaagataag ttattacgtc tggagtccga
     4321 gcttcatacc cgtgtgattg gtcaggaaga ggcgatcaac gctatcgccg atgcggttcg
     4381 tcgtagtcgt gccggcttac aggatccgaa acgaccgatc ggttctttca tcttcctcgg
     4441 tactaccggt gtgggtaaga cggagttggc caaggcgttg gccgagtatc tgttcgatga
     4501 cgagaatatg atgacccgta tcgatatgag tgagtatcaa gagaaattca gcgcgactcg
     4561 tttgatcggt gcgcctccgg gatatgtggg ttacgatgag ggtggacagt tgacggaggc
     4621 gattcgccgg aaaccttact cggttgtctt gtttgatgag atcgaaaagg cgcatccgga
     4681 tgtattcaac atcttgttgc aagtcttgga tgatggaagg ctgacggata acaaaggccg
     4741 cgttgtcaac ttcaagaaca cgatcattat catgacaagt aacctaggtt cttccttgat
     4801 ccgtgagaac ttcgagaaga tgacacccgc cacgcatgac aaggtggtag acgagacgaa
     4861 gatccaagta ctggaactgt tgaagaagac gatccgtccg gagttcttga accgtatcga
     4921 cgatatcatc atgtttactc cgctgaacga ggaggagatt cgcaagatcg tatccttgca
     4981 gttgaacagc gtgaagaaga tgttggctac gaacggtgtc gccttggact tcacgaacga
     5041 ggccgtggac tttatcgccg acaagggctt cgatcctcaa ttcggtgccc gtccggtaaa
     5101 acgtgtcatt cagaagtatg tcttgaacga gttgtcaaag gctttgctgg gtggaacggt
     5161 agaccgtaac cgtccgatcg tgatcgatcg gaaagacgat gggctggaat ttaagaacta
     5221 aagtagactt gaacgcttga cgttaagcgt ggagtttcta taaaataatg aaggtggaat
     5281 gatcctatgt gaatcattcc gcctttttat ttttcactaa taggtagata cggcttggtg
     5341 cgattatttc cgggtgggaa ccgtgcacca aaatgtagat ccttttccaa cgcttgactc
     5401 cacgccgatc tctccaccta aatgtttaat gattaattca cagatagaca gcccgagccc
     5461 tgtaccttgg gtgaaggaat ctaatttagc gaatcgctcg aaaacacggg agatattttc
     5521 ttccgctatc ccttttcccg tatcgctaac aaagaaataa atattgtttt tccttatttc
     5581 atatccgatc gttatcattc cctcgaaagt gtatttgcaa gcattattga tgaaattagc
     5641 caatacttgg gataaacggt ttctctcagt atggataatg tagctttccg caggcagttc
     5701 cgtgcggaat tctactcctt ccttgatctt gaatcggtaa ctccgccata gggtttgtat
     5761 aagctcgtta atctccactt ccgtataaag gaaatccaat ataccggctt ctatttttga
     5821 catatcgagt atgtcattga ttaaattaag gagtagctca ttgtttgcgt gaatgatttt
     5881 agcgaattct ttgatctcct ctttatcctc actttcgctg ataagggtcg agaaacctac
     5941 gattgcattc agtggggtcc gtatctcatg gctcatattg gcgaggaaag cacttgtcaa
     6001 ccggtttgat tcctctgcct tctcacgtaa gcggatcact tcttcggcca tatttcgttc
     6061 ggtgtcaaga atgtctttct tatgccgatg ttccctcatc gaaaggagga taagtagaaa
     6121 ggcgataagg gctatcgcca ctatctcgaa tggggactct atcatgaaac tcgggactac
     6181 tacgaggctc atttgcttaa aggtagaaat agggtaaagt ttggggttga ttgttgacgt
     6241 ggaatggccg tatgcttgat cggttttaga caggaatgat ttgtaggcac ctttcatgga
     6301 atgtttaaga tcgcttggcg tgattggact gattacatat gaggccttga ataagtaagc
     6361 cttgataggc ccgattttgc tccggagagc tcgggtactt gtggtacttt gtattttagg
     6421 ttccattgta atcataattt aatacattta ctgagttcta aaagaacttg agtatcaaat
     6481 gactatatgt aaataaatga tggagtgtat tttgatttta acacaaataa gactggcttt
     6541 agtgtttttt gtgatccata aagatattgg aagtctcttt ggggtactcg gttggaaata
     6601 tattctttca aagaaaatat catgcggaac agtaaattac ccggaagcta taaaaaataa
     6661 taggtctata tgataatcaa gtatttttat tacctttgct tcctataaaa cctaagctct
     6721 tttagaacta tgttcaagta agggcatttg cttttgttaa gtcacgtccg taaataagct
     6781 taattgtttt tgggatataa aatcaaaata tttccgtaca tttgccgcta ttcaaaccaa
     6841 ttaaacaaga ttaattatga gcacgaacaa tgacgagcta ctttacgacg aggatgattc
     6901 cgtaaaattt atccagaatt atcttcctca agaactgaaa ggaaagttca gtaatgacga
     6961 tatcaactat atcgtagact tgatctacga cttctatgaa tctaatggca tgctagatga
     7021 tgatggcgac gatgagatcg agatcgatga ggaagaggtt gtaaattatg taattaagaa
     7081 cgcccagaaa gacggcgtag gcaaattcga accggaggaa atcactttta tagtacaagg
     7141 agaacttgaa tattgcgatt cgatcaacat gtttgattga tatttgttat atatataaag
     7201 ttgtttaagt gaaattgtag aagatgatga ggaacattaa attattatct gttttactgc
     7261 tatgtatggc agtggtgttt acgagttgcg gaacgtggaa taacacggcg aagggtacgg
     7321 cgatcggtgt aggcggtggt gccgctgtcg gagctggtgt tggtgccttg gccggaaata
     7381 ccgcattggg tgccgtgatc ggtgcggccg taggtggtac agccggtgcg ttaatcggta
     7441 agaaaatgga taagcagaag aaggagctgg aagctaccct gcctgaggac acgaagatcg
     7501 agagcgtgaa caatggtgag gccttgaagg ttacttttga ctccggtatc ttgtttgcca
     7561 cgaactcaag tacgttgagc gacgcttcca agagtgcctt gcgtaacttc gctaccagtt
     7621 tgaaggccaa tccggatacg gatatccgaa tcatcggctt tacggataac accggtaagg
     7681 tggattataa ccagaccttg tccgagaaac gtgcgaagag cgtttacgat tacctgatga
     7741 tgcagggggt aagcacggat cgtatggttt atgaaggtaa aggtatacat gatcctgtgg
     7801 ctagcaatga cactcccgag ggtcgttcgt tgaaccgtcg tgttgagatc gtgatcttgg
     7861 ctaatcagaa aatgatccaa gaggctcaac aaggaacgct tcgataagtt tttttaagct
     7921 atccctgccg gaagcggaca ggttataggg tatgaattgg gggactgtct tttcgggata
     7981 gtcccttttt tgtttaaatc gcaggatagg aaggatgaag aagttgatat atattttatt
     8041 tgtgttgatt acgatcgctt ttgtcgtggc ggccatagcc ggattcgcta ccggacgtat
     8101 taatccggaa gggaaggagt ggatctcgtt tcccggattg gtgttattac cggtattggc
     8161 ggccaatcta tgtcttttct tgatgtggtg tgtctttagg agtcattggt gctgggtacc
     8221 tttggcggcg ttattgttga actgggagtt tttgatatcg atgttccaga tacgggtctt
     8281 cccaaaagag attccgatag ggaaagaagc ggttaaggtg attacctata acgtgaataa
     8341 tttcaatacg gacggaaaga aacagcttcc taatatagcg gattggctga gaaaggagga
     8401 cccggatatc gtttgcctcc aagaatgccc cgttgaatcg gccctgcgga tggattctgt
     8461 cgccaagacc ttatcgttcc taccgtatta ttgctctacc cgttcggcta cgaaagcggc
     8521 gggcaacgct attttcagta aatatccgat ccttcgtttt gagtctatcc tatacccgga
     8581 gtctagcaat aaatccttgt ttgccgtcat ggatatccaa ggggatagtg ttcgtgtatt
     8641 taataaccat ttccaaacga ctagcgtgaa tgccgtaaag cctcgtcttt accaagccca
     8701 tgcagagggt aaacaattgg aggaaaccga ggccgccttc catatggctt ttcagatgaa
     8761 gaagaatttc gtgaaacggg cgactcaggc ggattatatc cgtcagatgt tggatgccgg
     8821 ggaggggccc gtgattattt gcggtgattt taatgataca ccggcctctt atacgtaccg
     8881 taccgtgaaa ggtgatttaa cggatgggtt ccgtgactgc ggctctggtt tcgggtacac
     8941 ctttcgtcaa ttaaagcgta tatttcgaat tgattacata atttattctc ctgattttaa
     9001 gggtgtaact tatgattctc ctaatttaga ctacagtgac cataagcccg tcgtatggtt
     9061 aggatatgtt aattaacaca cccaaaagga tagttttaga acctttttca actcatgctg
     9121 ttttaatagt gacttatata taagcacaaa taatagtata aactgtttta aacgttaaaa
     9181 tgagatgaaa aagatttttc ctttttttct gttagttctt ctgttggctt cttgccaaaa
     9241 ggacccggac atgtcgaaat tggacaatga ttttctggtg ttcacgaatc acgataagga
     9301 cgcgaaattc gaatcgttca ctacgttcta cattccggat agtgtattgg ttatcggcac
     9361 aagcgagaaa cctcagttct ggacagccaa tgaagcagac gatattatca ctacattggt
     9421 gaataatatg gaaagccgcg gtttcaaacg cacgctagac aaagataacg ccgacttagg
     9481 tctgcaagtt tcttacgtac aaagtactca atatttcgct gactacaacg atggctacaa
     9541 ctacccgtac tggtggtgga actatccggg atattggagt ccgggttact ggggaccagg
     9601 ttggggaaat tggtattacc cgtatcctgt agtgtatagc tatagtgtag gttccttgtt
     9661 gacagagtta gtggatttgg atactcctgc cgcttctaag gcagacgcta aacttccggt
     9721 tctttggact gcttacatga gtggcttgtt gtctggttcc gataaattcg atactcagct
     9781 ggctgttcgt gctatcgagc aagcatttgt acaatctccg tacgtaaaga aataataatt
     9841 cgaatgatta aaagtttgag attctatgaa aaagataaat aaatcaatca agttaatcgc
     9901 tttactcgta gtttgtatgg cgatgcctac tctggctggc gcccaggttt tgaaaaacgc
     9961 gtatttcaat gtagactggc aaatcaactc tccgttcggt caagactttt ctaagaagac
    10021 cagcggttgg ggtgctcacg ctgagggtgg ttactatgtg attcctaatt tcgctatagg
    10081 tgcgttcatc tcttatcata caaataatga gtatgtggac cgccagacga ttccggtaaa
    10141 ctcaacatcc gtaatcactt ccgatcaaca gcattctatc ttccagttgc cttttggtgc
    10201 ggctttccgt tataacttcg ctccggaagg acaattccaa ccgtatgttg gcgctcagtt
    10261 aggtgctagc tatagtgaga tgtctaccta catgaacgtg ttgaaggttt acgatcgtaa
    10321 ctggggattc tatgtagctc ccgagatcgg tatgaccgtg tacttcacac ctcagaaaca
    10381 gatcggcgta catatggccg cttattataa ctacgctacc aacaaggggg atgtcctcag
    10441 ctatcatatc gatggtttga ataactgggg tatccgctta ggtctagcgt tctgatagac
    10501 aacgtttgtt cttttaagtg ttttatgtag tttagggaaa cggagggcag tgaatgtctt
    10561 ccgtttcttg cttttatagg atctgtagtt tcaccccgaa tgaaaggctt aaataatctt
    10621 ttggcttcaa gtagctgttg ccgatagcgt ttattatata caaatcgcag gtgctcaact
    10681 catagaagaa gctgatggat ttatgccagc tactatttgg attcagtttg agcgtgatcc
    10741 gctccccgat aaagatatgg ttacggatgc gggtggagaa ccaataatat cccgggggat
    10801 acttattcgg ttgcttggcc cagaaatccc ggtcaaatag gaaatttacg tagataccgc
    10861 aacaaagagg ctcgaaagat actttttctc ccagatcgat attccaagga aaatagtttt
    10921 gtttcaaggt gaaagtcacg ttcgcgtgat cattcgcgtt gcgggggacg atacccagca
    10981 acatatccgt ttcccaatga ttccggtaat aattccaacc ggtacccacg gagagcatcg
    11041 ccatggaacc tgcgaattgt actttcgtat agcgagggat gacccgttgc catgcgttct
    11101 cgtaccgttg cactcgtttc gtgtatttat cctcttgcgc atggagtgta aggggaaaga
    11161 cacaagttaa gaggagaagc ttaaaaattg accacttcat acatataatc gtcaggggtt
    11221 aaggtaaaaa gaagataact tcgtttggcg atattggcgc aaccgtagta gataatacca
    11281 tcctcaaaca aatcggctgc cgatacgcaa tggttatgcg catgcaagca gaacattaaa
    11341 gatggtaatg tcttgatata aagttggaac acgtctttca cgttattgtc gaactgttcg
    11401 ttcccgggag gggcgtgcat gactacgatc gtgcgtttat tacgggtact atccgctatc
    11461 tcattcttta ggaaattaaa atcgggtacc ggatgggaat aatcatactc gatagcgttc
    11521 gtattgaggc atacgaattt cacgtcgctc acgacaaacg agaagttctc attcccaaag
    11581 attttacgaa atacttggtc gccattaccg atcacgtcgt gattaccgat caaccctacg
    11641 taaggcactt ttagtttgga caagatatca tcgttccact cgaattcctt ctttaagccg
    11701 aactccgtat aatctcctcc atggataatg aaatcgatgc tatctaattg attaacgtac
    11761 ttgacgaaat cttccgtctc gttataactt cgctgggtat cgcccataaa aataaaacgg
    11821 atcgtgtcct tcccttcgca gactttctcg atacgctcga tattggtcgg gttgatctcc
    11881 cgggaagtat cggaatccag acggccgtca tacggatgat aatcgattaa gtcgcaagcc
    11941 gtgaggagcg tagcggcaga aaggcatatg tatttcttta aaagcatagc atcctaactt
    12001 ttttatatgc aaagttagga tgctatcagt accaaaaaag gtcatttctg agcttatact
    12061 ggtctaaaat gtatattcta taaagcgaat acttgcttta tttccgtgaa gtcagataat
    12121 acgatatcgg cagtctcatt tcctttataa gcgctccaac caatactttt tagccagatt
    12181 gtctggcatc cgatccgggt ggcggggacg atatccttat cataggaatc acctacgaca
    12241 acaatctcgt cggcgggaaa tcccagttta tccactccta atcggaagat cgccgggtcc
    12301 ggcttacgga tacctacgac cgccgattcc acgatagcgc cgaataaatg atccaaaccg
    12361 aaatctttca acacggattc tatgttccca tagaagttcg ataccaatac caatgggtaa
    12421 cgttccgcta attgctctag aatggggcgg gcgctatcga ttgccttccg ggcgtattcg
    12481 taacaccaat ccgctaattg ttccggtaac tccggggtaa tcgcctcggt ggataaatgc
    12541 ccgttctctt tcagccattg gatttgtaaa tcgcttttca agcgcaacat atccagaaac
    12601 gtatgatgag gcttcacgat cggattcttt ccaagcgttc tttctccatg tacataggca
    12661 tcacggaaaa ctgctttgga tacgggaacc ttcaaggcct catacgccat ccagatcacc
    12721 tctgcccagt gcatgccatt actgtctatc gttccgccgt aatcaaagag gattcctttt
    12781 actttgtcta aattgaacat aatcgaatgg ggtaaaaaac gttataactg tttgctgaaa
    12841 tcttcacaaa tatgctcatg ctttttgatc atatagagca acatcgagtt taatacggtc
    12901 agctcgaata cgaaatacag ccaaggcatg tcgatgaaaa ggctgacaaa caaagcgatc
    12961 acccgggtat tgaatgatag catatttgta tatttcatta atggcaggct ctttgttcga
    13021 aaagccttac ggaaccattc cggcgcttgt ccgttgtatt tctcacggat gatgttcatc
    13081 atgtgttgga atttaggtgt ccatgcttct tgacctaccg tataattaat gtagaaggtc
    13141 tcgaacaatt tatagataaa gtcatgtttc caactcatct tcttataatt ctccttcaat
    13201 tggggagagt gggagagctc gctacccgat ttacctttca agaacaacaa gtgaatattg
    13261 cgataataat ccgccatggc cgcttgcttg ctatggaaga atcccgtcgt agccgccaat
    13321 agccagatcc atattcccca ttccggcgtg aggcgtaagc agattgccgc atagatagcg
    13381 ataaaccaga aatcgccggc ggcaccgtcc aagatacgtc ccaaggcact tttctgtccg
    13441 gtcatacggg ccaattgtcc gtctgcgcta tcatacgagt ttgcccagat taacagtaac
    13501 atgccgatca cgttgatagc gaggctctgg aaatagaaac agatacctgc cgctatgccg
    13561 ataaagatgc tggcgatcgt gatactattg ggcgataccc ccaatttatt aaagaacaaa
    13621 gcccattggt agccaatagg acgatagaaa tgaatatcga taaactcctc ggtgtccaaa
    13681 gattttaagg ttgactccag actgggagta gacttagtct cactcatgat tgattttgtt
    13741 aaaacgattt agatgtgttc tcgcataaga tcccagatac gacgtgcgat gtttggagcc
    13801 gcttcttccc ggcaaggggc gaaactaggc caatcattga aatcgataat tcgcatgaca
    13861 ccatcctcgg agacgatgca atctcccccg taaatatgta tgctcaatac ctcggctgcc
    13921 ttgtggcaga gcagacgaag ctgcgcttcg tcgaagggga tccccttcgc tgtaccattg
    13981 ataacttcta agccaaattt actatgatgc atgttcgatg gatagaacca ataaaagaaa
    14041 tcggttccag ctaccccgta aaatttcacc aaatcgccta ccagatgttc attgattacc
    14101 gccgacggga tgccacggat agcgtattcc ttcagtatgc ttctcgcctc ttccgggttt
    14161 ctcacgtagg tgacgtcttc ccggtggata gcgtggaaat ctccccgttt gatccagcaa
    14221 ttaaagaaac cggctttctc aagggcttct gtcggatcct catctgtccg taagattaag
    14281 ctttccggat gggagatatg attggataat aggaggcggg tcattttctc acgggtacaa
    14341 ttctcgatcc cgtaacccga gttcaccacg aaataatttt tatcctctag ttcttgcagc
    14401 ttatggatgg acttccagtc tcttaccata ttaaagatac ccttttcctt cgggtcttgt
    14461 agcagcagat ccgattcgat atattcgttt acatcgcatc ccaattttcg taaatgctgg
    14521 gctgtcaagg cgaagatcgc cgcgtcgttg ccgatatgat tgggggagaa ttgatttcct
    14581 ctgcggatac ctgctaaagt taatttactc attgttagac agtattcttt atgactttaa
    14641 aaatgattcg gctttcaaaa tgtcatcggc gtgatccacg tcgatgatct tgctgaaagg
    14701 ataggccttt agcctcaacc cctcggcgat gagctgccgt tgataattgc gcattctcga
    14761 cattccctgc gagatggcgt tgttcaatac acccagagcc ggacgcctca agcaatagat
    14821 acctcccgat atgtaacggc aatcaccgtc tgcctgatct aggaaattcc ggatgtaaag
    14881 ttcgttgtct gtttctacat ataagggttt ctcgtcatca ataaaatcag tgacggccat
    14941 caatccgtcc agtttatcct cttggatgaa ctgttggata tagccgctga actcttcttc
    15001 cttgaagatc gtgtctacag tagttaaaca aatcttatca ccgtccagat aatgactcag
    15061 ctcgtagaag ctgtgcatag agctgggggt ggattttacc aataggtaaa agggtatagg
    15121 tagtcgcagg gccttcaggt aatcctgtac ctcggtcatc tcctcgttta cgatgatact
    15181 gatagaggta gcgttatttt tcaaaaaaac gtctatcaac cggtctatca gagcgacacc
    15241 gttgagtcta accagaggct ttggccactt aacaccttct tgcgccaagc gggagccttc
    15301 gccggcggca atgatcgcgt aatccataac ttttattagt tcaaataata atttcgcaaa
    15361 gttacgagat ttctgagata gttttaggct atatcgttga tataattggt caaaatttct
    15421 ataaattagg actatttgac tagaacaaca aagacgttat aaagagcttg aatgtttttt
    15481 tgaaaataat tatcgtttta tagttgctaa ttcaaataga atgctttcct ttgtgccatg
    15541 aacaaaagat agtttgtata gctcttttat cttttagcat ttattcatca gcgatgataa
    15601 tactttcttt tagagattga cttcaccaac catccttgtt ttattattaa tttttatttt
    15661 tttatatcat tttcgtatga atatttacat tggaaacctg aattatcggg taagagaatc
    15721 agacttacaa cagattctgg aagagtatgg tgttgtagac tcagttaaaa tcattgttga
    15781 ccgtgacaca aaacgttcta agggcttcgc tttcgctgag atgcctaacg ctgcagaggc
    15841 tcaaaaagct atcgaggagt tgaaccaagc tgagtacgaa ggtcgtcaga tggttgttaa
    15901 agaagctatc cctagacgtt aaattttaga agaaagaaat ttttaaaata agacgaaaaa
    15961 gcggggaaac gaggtgaaaa cttccgtttc cccgctttct tttttcagtg tattttgttt
    16021 atgttcgcga gaaattttaa gagtgatgaa gaatataggt gttaggagtc tcattgtggg
    16081 tctttgcttg atgggattgg ggagttggtc tccctcgctg aaggcgcaga tcgcggatcg
    16141 tgtctataag acggattatc atatcgaccc ggagaaggcc cgggagttgt ccgtggagtt
    16201 ggataatatt agcttcttca aggataacga gtatacgggt aaatttacca aagggtattc
    16261 gttgccgggg ctttgggtac aaggcaaagc ggtttattat cccttgcgga atatcaagtt
    16321 ggaggcgggt gtccatatgt tgatctatca tggggcgaat aaatatccga gcatggctta
    16381 tcaggatatc gcttattgga agggagacca ataccaaaaa ggggtacatg tgttgcccta
    16441 tttccgggcg cagatggccc tctcggatca tgtgaacatc gtgctgggaa atatttacgg
    16501 cgcttccaac cataatttga tagagcctct ttataatccg gagttgaatt tgacctgcga
    16561 tcccgaggcg ggcttgcagt tgttgtatga ctcgaaggct ttcgacttgg atgtgtgggt
    16621 gaactggcag agctttattt tccgggagga tgtgcatcaa gaggcgttta ccgtcgggat
    16681 ctcttcgcgg gtaaagtaca acgacccggc ttcccgtttc catttctata cgccggtgca
    16741 aggattggtg cagcataggg gaggcgagat cgacacgatc ttcaacaatt ctgtgcaaac
    16801 cttgatgaat ggcgcgatcg gtgtcggagg tgtatggaat accggacatc gtattttcaa
    16861 gaacttgaac gtggaactgg atgctaccgg ttattatcag caagcgggag agatatggcc
    16921 ttttgacagc ggatatggct tgtatgcccg tgcttccgcc gatatctatg attttcgggt
    16981 gaaaacgtcg tattggacct gcaaggattt catctctatg tttggtagcc cgtttttcgg
    17041 ggcggcctcg atgattgatg agggggttac gttcgaccgt ccgcaaatga tctatctggg
    17101 ggtggaatat tcccggcaac tagcgaaggg tttctcgata ggagtagatg tggacgtttt
    17161 tcatcatctc tccggagata tgaatgatgc ggatggagta aaacaaccga tgggaaacgc
    17221 cacgagtttt acggcagggg tttacatgcg tatcaatccg tctttcttga ttaaaaaatt
    17281 ctgatcatta ccttcataga aaaacacagt agtattcgat tgtgaatact actgtgtttt
    17341 tctatgaata ctattgtgtt cagccgtgaa tacaatagtg tttttattca attactaaat
    17401 caatcttttt cagtgtctta tcgtccgagg aacctccata taggatttgg tatttacccg
    17461 ggcgaacctc catggtctgc gtattgtcat tgaaggattg gaaagctttc ggttccaatt
    17521 ggatgctaac cggttgttcg ctgccagcct tcacgttcac acgtttgaat gctttcatcg
    17581 cttttagcgg tccggcagga tcgttcgggt tcttgatgta gatctgagcg acctcgtcac
    17641 catccatctt gcctgtattg gcgatatcga aggagagggt aaccgattcg ttggaagcga
    17701 tcttatcctt tgacaactta gcgttcttat aatcgaatgt tgtatagctc aagccataac
    17761 cgaacggata aagcggagtc tgcgtcatgt aacgataggt acggcccttc atgctgtaat
    17821 cttggaagtc cggaagctgg tctacggatt tatagaacgt gatcggcaag cgtccggccg
    17881 ggttatagtc tccgaataaa acgtcggcca cggctgttcc accttcttgt ccgccatacc
    17941 aagcgttcaa gatagcgttt acatgatcgt tctcccagtt caatgccaat gcgctacccg
    18001 tacataccac gtatactaca ggctttccgg tggctaccaa ggctttgacc atttccttct
    18061 gtacggctgg gatctcgata ttcgtgcggt cgcctttccg gaaaccttca gcgtctaccg
    18121 gcatttcctc accttccaga cgtggagaga taccacctac gaatacgatg acatcagcgt
    18181 ctttaacctt gctggccgta gcttggaaat ctacgggtgt gcgtacgcct accgtaaagt
    18241 tcagatcagc gctacccgtg cgttgcatgt attcgatctt tatgggatat ttctcacctt
    18301 tcttagcgtt tagcgtatag agtttttccg ctccatattc gttttcccat acctcggcga
    18361 ctttagccgt atcgatatac aggcggaatg cgtcgtttcc ggatagtttg aactcgacag
    18421 gaccatctat cggagactcg aattcacccg taaagcgagc cgtgaaattc gtcaagttca
    18481 cgttcggggc gaattgggtg ttacctccgg tggtataatg aagctctttc gctaatccct
    18541 tgtaggcggg ggtaccctcg aactcggtat tgttgaagaa ttcggaggcg aaaccctgtc
    18601 ccgccgtgga agatacgtgg ctacctaggt ctgtcacgac aaaatcggca gtatggttgc
    18661 aacccagctc gtagataacc tctgcgttcg ggactttatt gcggatacct tccacgatcg
    18721 taacggtctt gctagggaag ccgttgtagt tggcccatag catggtagag tccgccgcgt
    18781 tcggtcctac tacggcgatc ttcttgatat tcttgtccag aggaagcata ttattcttgt
    18841 tcttcaacaa aacgatactt ttacgtgcca tatccagtgc cttggcgata tgctccgggc
    18901 tctcgactac gctgtaaggt atcttagaat aaggaacccg ctcgtccgga tcgaacatac
    18961 ctagctcgaa gcggcctttc agtaggcggc gtaaggatac gtccagatct ttctccgaga
    19021 tcttaccgtc ggccaaggct ttgtttagcg cacggtagct accgccacat tctaggtcgg
    19081 taccgttcaa tacggcgtcg gcggatgcgc tctcagcgtc cgggtgcgtc tcatggcgag
    19141 gcgtattttt gtcttttctc cagaaatcat cgatagcacc gcagtcggag aggatgatat
    19201 tgtcgtatcc ccagctatta cgcaagatat cgatcaataa tttgtcgctg ctacagcaag
    19261 gtttgccctc gaaacggttg taggcgcaca ttacctcttg tacatcgcct tccttaacca
    19321 atgcctcgaa agccggaaga tacgtctcgt acaagtcacg aggggtagct tctgcgttga
    19381 attcgtggcg gttccattcc gggccgctgt gtacggcgta atgcttggcg caagcgtgtg
    19441 tcttgtaata attcggatca tcgccttgca atccgcgggt tacggctacg cccatcttct
    19501 cggtcaagta agggtcctcg ccataggttt ccataccccg tccccagcga gggtcacgga
    19561 agatattgat attcggggtc cagaaagtaa gacctttgta acggtcgtac tccttgtctt
    19621 tctggtattg gtggtatttg gcacgggcct cgtcgctgac catcgtgaag gtctcgtgaa
    19681 cggcgttatc gtcgaaggta gccgccatgg cgatcgcttg cgggaatacg gtcgcacgtc
    19741 cggcacgagc cacgccgtga agagcctcgt tccaccagtc gtaagtcggg attcccaaac
    19801 gctcgatggc gggggttacg ttcatcattt ggccgatttt ctcctccggt gtcagccggg
    19861 atagtaagtc gtcgatacgt tcctccaagg gaagttccgg attccggaaa gggtaatctt
    19921 gttgtttttc actacaagag gcggtgagta ggagggtgat catcgctact gtcagttgtt
    19981 tcattttcat gttattaaat tttagatatt gtttatctta cattattact tattgtaaac
    20041 tattttaaga tagatcgtta tctttgatat tgatgatgca aaactacgat tttagaagca
    20101 ttttttcaaa caggaatact taaaataggt tactttcgtg gttattcatt taaaagccct
    20161 acttttgccg taacagatta aaacacgaaa gaatgatgaa gaagtatcta tttttgttac
    20221 taataggggc cgctagcctg acggcctgcg gagacgatga cgatcccgtt gttccggaat
    20281 tgaataagct aacgaaagtt tcttgttata aagacggagc ttcaagcccg ctttttaccg
    20341 ctgatatcaa ttatatgaat gacgggaaaa tatcgagtat atctttccat ggagataaag
    20401 agtttcgtct tttctcttct gacaacaaat atttgatgat agatatctct accggggacg
    20461 aactaggaga atatatatta agtggaaatg tgatcacggc aaagaacgtc ttgaggaaaa
    20521 attcgtatgc gagtaatgag gtctatgtga gtgatgaata taagtatggt tattccggat
    20581 ctaatctggt gttgacctca tgggtagctc gttggccgaa agaagacggt caagggtatg
    20641 agagtgagga ttacagggaa tatgataagt tttattggga aaacgggaat gtggtaactt
    20701 tttctcggaa tcaggatcgg atggagtatg agtatagtac ggtggagagg cctgaaaatt
    20761 atcctctacg tgtgatcggc tcttttgctc cggttgattt tgaagctgtg actcccttga
    20821 acctattata tggtgttcag aaccggaatc ttccgatccg tgcctacacc tatacgatcc
    20881 ctaaccagag cgaggtgaaa gctgagtaca aatacaccta taccaccgtg ggagattata
    20941 taatgtgtat gactatcgat gagaatgacg gaggaaccgc aagctcttat aagtatactt
    21001 tcgagtataa tttcgccgtg aagtaaggag acatgccttg tttggtttaa ttaacatacg
    21061 catatgcagc atttccgccc taaaacgcat ttctaatttt atagaattaa aaggttgatt
    21121 agtttaattg ataaacttag aaaggaagta ttatgaacgg attctttaat tttaggaaat
    21181 tagttgtagg tgtaatggcg gctacttgtt ttatggggtt tcaatcttgc ttggacgatg
    21241 atgatgatta tccttacagt aaagtgttgc cgaatgcgtt ggtgacggtt aagccggtcg
    21301 atgatggttc atattttctt caattggatg atagcacgac cttgttgcct gtcaatatga
    21361 cctcttctcc cttcgggcag aaggaggtga gagcgttggt gaattttgac gagacaaacg
    21421 agtctagcgg aatttacagc aaggccgtaa atattaattg gatcgacagt atccttacaa
    21481 aaccaatcgc tccggatttg ggggtgacta gcaacgattc gatctatggc tctgaccctg
    21541 tggagatcgt gaacgattgg gttaccatcg ccgaggacgg atatctgaca ctccgtttca
    21601 ggacgatctg gggagaccgc aataaggctc attttgtaaa cctactgaca ggcaaggacc
    21661 cggagaatcc ttatgaggta gagttccgcc ataatgctta tggcgatgta tatggcgcat
    21721 atgcggatgg actggtcgct tttaaattgg atagccttcc ggatacgaat ggtaagacgg
    21781 ttaagttgaa attaaaatgg aagtcattcg atggcgataa gtctgtggaa ttcaattatt
    21841 gttcacgcaa gtctactccg gcaaaagcat ccatagctgc cgagagaagc gccttaaatt
    21901 tgaaataggt cggtttgatc gtttaaatag atggggattt ggcagggagt gaatctctct
    21961 tgctttttga aagttctttc ctagtgatag ggaaggactt ttttatggat agaaacaaaa
    22021 aaggactcta agaagagtcc tttttattcg tgggcagtga tggattcgaa ccaccgaagg
    22081 cgaaagccag ctgagttaca gtcagcccca tttggccact ctggtaactg cccattccaa
    22141 tatattttct tgagcctctt gtcggattcg aaccaacgac cccgagatta caaatcacgt
    22201 gctctggcca actgagctaa agaggcatct gttattcgtt tgcgggtgca aaggtagtaa
    22261 taatatctta cgatgcaata gctggaggta ttttttttca aaagggaacg aaaaaagccg
    22321 tccgggacaa ctcccgggcg gctcttctct acacgtaact tacatcaaat taaatcaata
    22381 tctcttacca acggtttccc agtcgataat cccccacaat gcgttcaaat gatccgcacg
    22441 gcggttctgg taatccagat agtaagaatg ctcccataca tcgaatccca tgatcggagt
    22501 caatccctta acgaccgggt tactaccgtt gggctctttg gtaattgaaa gtttgccgtc
    22561 tttatcttta gccaaccata cccatcctga gccgaacaag cctgtaccgg cagccacgaa
    22621 ctctttctgg aagttctcga acgatcccca cgtagacttg atagcctcgg ctagcttacc
    22681 cgtaggctcg ccacctccgt tcggggagaa ttgggtaaaa tatagattgt gattcaatac
    22741 ttggccggca ttgttgaaaa tggctccgtc agactcacga acgatctgct ccagcggagc
    22801 gttctcgaat ttcgtgccct caatcagctt attaagggta tttacatagt tcaataaatg
    22861 ttttccgtaa tggaaatcaa ttgtttgttt gctgataact ggttctaaac cgtcgtttgc
    22921 gtacggtaac tggattaact cgaatttcat aacttcttct tttttatctg ttatttgact
    22981 atttgtgatc attaataata aacttaaaca taatgtaagc attgtcttct agttttttat
    23041 gttgatttac tatataaaca gagccgaggg gatgaaagtt ctgggttcgg tgatgatttt
    23101 ttagtgaaaa tatgtttgcg gctaaagttt tatagggaaa actatgcgtt atatatcgcg
    23161 aaagtttcta tttttgtgcg ctcttaagct tttattaatt agtaaaacat atttgtagat
    23221 ggtaaagaaa gttgggaatt taattccaaa cacctttttt attacaaaag gaagtggcga
    23281 atcagacttg gagaaacacg ctggttctta ccacatggct ctttatgacg ccggtatctc
    23341 tgattttaat atcatgacgt attcgtcggt gatacccgct acggcacatc tggcaaccat
    23401 ggatgaacta gaccttcctc catttggttc ggaaatgaaa acgatcatgg ctgtatccca
    23461 tggatatcag gatgagttcg tgtctgctgg tgtggtttac gcatggatgt ataaggatga
    23521 gaacttcgac gagaaggttg gtggtctggt gtgtgaggtc agcggacgtt accgtatcga
    23581 ggagcttgag tctcgtctga tccgtgttat caacgatctt catcagaaga cgtatgggaa
    23641 gtattatctt ggagagctta actttatcac cgagggaatc acgatcgaga aacgctatgg
    23701 aacggcgttg gccgcccttt gcttcgtgga tttccttcaa ccggagatcg aggaataagt
    23761 cgtgttgagt atttttgtga tatttataga gccggttcct ttcaagagcc ggcttttttg
    23821 ttaactttga gcaacaaaaa acatataaat attgttttcg tgatatgaaa aagataatta
    23881 atccgtggga agggctggac ggttatatgt gtttcggttg tgctccgaac aatccgctgg
    23941 ggctgcatat ggagtttttt gaggatggtg acgatatcgt ggcgttctgg aagcctcaag
    24001 gtacttacca aggatggctg cgtacgttgc acggaggtat acagactacg ctgatggatg
    24061 agttggccgg ctgggtggtc ttgcggaagt tgcagacctc cggggtgact tcacgcctcg
    24121 acgccaagtt tatgaagagt atctctacgg acgagcccca gctgacgata cggggacgga
    24181 tgacagaccg gaaacggaac gccatcttca tagagaccga gatctataac tcggcgaatg
    24241 agttgtgtac ccgtgccgag atggtttatt tcatcacccc gcaagaacgt gcgatggagg
    24301 agtttggttt ttgcgggtgt aagactgagg atgaacatta gtataaataa aaagaaaagt
    24361 taggttatta tgaagtatgt tggggctcac gtgagtgcgg tcggtggggt tgagaatgcc
    24421 cccgttaatg cccatgagat cggtgcgaag gcttttgccc ttttcacccg gaatcagagg
    24481 caatggaagt cgcagccgtt gaaggcggac agtatccatt tatttaagga gcggtgtgaa
    24541 gcgtacggtt acgatccggg atgtatcttg ccgcacgata gctatttgat caatctgggg
    24601 aacccggacg ccgagggatt gcagaaatcc cgtgacgctt ttctggacga gatgacacgc
    24661 tgcgagcaac tgggactgaa aatgctgaat ttccatcccg gaagccattt ggggaagatg
    24721 gaggtggata cctgcctgtc tcgcatcgcc gagtcgatca atatcacgtt ggctcagacg
    24781 agtggcgtat gtgccgtgat agagaatacg gcggggcaag gctcgaactt gggatatacc
    24841 ttcgagcaga tcgcctatat tataaacgag gtagaggata agagccgggt gggagtatgc
    24901 ctcgatacgg cgcacacgct tgccgccggt tacgatataa agacaccgga gggattttcc
    24961 gagacattcc gtcatttcga cgaggtggtc ggcttttctt atttaagggg gatgcacttg
    25021 aacgattcta aaaaggagct gggatcacgt gtggaccggc acgagagtat cggtaaaggc
    25081 ttgatgggcc ttgatacctt ccgcatgatc atggcggacc cccgtttcga caatatgccc
    25141 ttaatcctag agaccccgga cgaggcgctt tggccggagg agatacagct tctatataaa
    25201 caattaaaat cttgattata tgttcatttt aatgcctgtc atttttgtct taggaatcct
    25261 cgctattgcc ttggaggata agatcaaaat aaataaagcg gccatagcgt tgttcatggc
    25321 tatctctatg tggatgatat tgatgttcga tgcctacaat attttcgtcg aacgctccag
    25381 tacgatcttt caagagttct tgacccagaa cccggagatg gccagcttgc ccccgcatga
    25441 gcaatttatt aattttatat cgaaccgtgc gattgtttat catttaggaa acgtctccga
    25501 gacgcttttc ttcgtgatgt gttccatgtt gatcgtggat atcgtggata agcatggtgg
    25561 ttttagggcc gtgaccgggt atatccgtac gccgaataaa cgtaagctgt tgtggtatat
    25621 aagtttcgct acttttttct tctccgcctt gttggataac ttggcagccg ctatcgtgat
    25681 catggcggtg ttgcgtaagc tggtaccgga tcgtacggat cgtttgaaat atgcctgtat
    25741 ggtgattata gcggcgaacg ccggtggctc atggtcgccg attggtgatg tgacgaccat
    25801 cttgctttgg gtcggaaaga atatctcggc gatgcaccag atctctcacg tatttatccc
    25861 tgctttggtt aatatgttgg tgccgttgac gatcgcccat ttctggttgt tcaagaaagg
    25921 atctaccttg cgtgtgttga gcgaggagga gcaaggcgac gagtacatac cagagatacc
    25981 gaaccgctca cgtcggatga tctttgtgat cggcgtgctt tccttggcgt tggtgccagt
    26041 cttccagatg gtgacgaact tgccgccgtt cttgggcgtc ttgctgggat tggtgatcct
    26101 ttggttctat acggatttga tgtatagcaa gctgcacatg catgagtccc agaaactccg
    26161 tatttcccaa ttgttgccga atatcgattt ggctacgatc ttctttttct tggggatctt
    26221 gatggccgtg ggagcgctgg agacctccgg gcagttgggt atcatgtccg ctttcttgga
    26281 taagcatgtg catgaaccgt atctgatcag cttcgtgatc ggtgccttgt cctcctgcgt
    26341 ggataacgta gccttggtag ctgctacgat gggtatgtac ccgatcgtgg agcaggtggc
    26401 cgacttatcg ccttatgccc agttcttcgt atcggacggt ggtttctgga ccttcttggc
    26461 ttattgcgcc gtgacgggtg gtagcatctt gatcatcgga tcggctacgg gcgttacggt
    26521 aatgggattg gagaagatcg atttcatgta ttatacgaaa cggttctcta tcttggcgtt
    26581 gatcggctat tgttgcggcg ccggtgtata tatgctttta tttgcttaaa actttattta
    26641 tatgaagaag agttggattt tattaaccgc ttgcgccgcc ctgttatccg gggtggaggc
    26701 tatcgcctgt accggtttgc tggtgggcaa gaaggcttcg acagacggtt cggtaatgat
    26761 tagttatgcg gcggactcgc attccctgta tggggagatg tatcgttggc ccgccgctac
    26821 atggccgaag ggcgccatgt tggaagtgaa ggaatgggat acggggaaac cgctgggcaa
    26881 gatcgcccaa gtggagaaga cctattccgt agtgggtaac atgaacgagc atcaggtggc
    26941 tatcacggag agtacgttcg gcggacgcca tgaattggtg gatacgacgg gtatcatgga
    27001 ttacggtagc ttgatctaca tcgctttgca acgttccaag tcggcccgtg aggcgatcaa
    27061 ggtcatgacg gacttagtaa aggaatatgg ctattacagc agtggcgaga cgttctctat
    27121 cgccgataag aacgaggctt gggtgatgga gatgatcggt aagggaccgg gtaacaaagg
    27181 tgccgtttgg gtagcgatcc gcatcccgga cgattgtatc tcggcgcatg ccaaccagtc
    27241 ccgtatccag cagataccgt ttgacgataa ggagaattgc atgtactcgc cggatgtggt
    27301 ttctttcgcc cgtgagaaag gatatttcaa gggaaaggac gctgatttca gtttcgccaa
    27361 ggcttattgc ccgtatgatt tcagcgcctt gcgtggatgc gaggctcgtg tatggtcttt
    27421 cttccgtaaa tatgatacca cgatggatca gtatatggat tttatcaagg gtgatccttc
    27481 caaggagccg atgcctctgt atgtgaagcc gaatcgtaag ctttccgttc aagacgtaca
    27541 gaatggcatg cgcgaccatt acgagggaac ggatctggat atgacgaaag atgccggtgc
    27601 cggctcgtat aaggttcctt accgctggcg gccgatgacg ttcgaggtag acgggcagga
    27661 atatacgaat gaacgtgcca tagcgacgca acaaacgggc ttcgtgattg ttccacaaat
    27721 gcgtaa
//
LOCUS       DBMDTB010000048        27539 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_630_length_27539_cov_12.092281, whole genome shotgun sequence.
ACCESSION   DBMDTB010000048 DBMDTB010000000
VERSION     DBMDTB010000048.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 27539)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 27539)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27539
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_630_length_27539_cov_12.092281"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            323..733
                     /locus_tag="ACZPB4_09210"
     CDS             323..733
                     /locus_tag="ACZPB4_09210"
                     /inference="COORDINATES: protein motif:HMM:NF046666.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098428.1"
                     /translation="MIQLSAKIEYKGIYNKNNNDLINDQFSLINVEGLNASSQVAIFN
                     TSSVENGVFEALTYPSEDKPTTFYTYEISDANKNILLSVQQNGSEIKSFSFPANKFIK
                     GNYYEIKGLYEPSTEIEWILEEVGNENVALDPFE"
     gene            770..3511
                     /locus_tag="ACZPB4_09215"
     CDS             770..3511
                     /locus_tag="ACZPB4_09215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4906 domain-containing protein"
                     /protein_id="HIR1098429.1"
                     /translation="MKQYIMFLLGLLILSACTNDEYLAQRTEVEEGIPTVVKLSVTIP
                     MSGKIETKAFSDSGVADLYVFSFKKDNDEFITAQKYTELSGSTISFSTLSGEQRIFAI
                     GNVDYDMFPGLSERLESWLGNNHPSKSDLTSLLAEVGGDKAVQFANTTSLVSGLWNNE
                     DDTKDYCTVKVDGTLVEKGKIYLKRVAAKVTFKIEVADGREFKLKSYQVCEVPKKVNV
                     WEGSTSEEIVSYSTQELTISRDEGFFTFYMPENIANGKEGCNSADDREKLSKGSLRNS
                     PPEGRVFTYVDKPATYVLLKGSYYAKDTDGKETSAEVVYCIHLGLGAGSSDKVDHKDF
                     STKRNMNYTYNIQIEGVESIKTEVTATDNNVWRQEGDVTVSGEGKSIQLDAHFEARKI
                     TFHKSDFKTTDLRVYVKDPLTNFQLTEFSELKEESKNWVSFKSLKDVPVEETYKYPDE
                     KHVSELLSVEELLTELNKWAKGENSLLAPTNEGAIEFVCFVNEYYYQSIMWPEFVNTL
                     DREFFIMDKTQKQTSGGNSTLTSDASFVIKQHSIQTIYDLNKGEDYNAWGIETINETG
                     LLNTTTNPSKIKDIAYGRLNLPDFSGKGWSTFLDYSKESNSNQMKDDYKNAYYACLQR
                     NRDENGDGVIDSKEKKWYLASSGQYISLWLGRSSLSAESSLFNIDDWVKEGFAKNIPA
                     KYHYIPSNNDGKVVFWAEEGITIGNDDSHTTGKIRNYRCIRDLNMKGMDENNLDRKKA
                     PETLFKISSVDPKALTVTFDYLNANSLKPAPSMNELDPHNERDNDINRVYKSFCIVRG
                     SVSSNQVGGTWKAKTNLTNPCNRIMNEHGWRMPNQAELSVIYLVGTDASAYGSYKKNE
                     FNGLKGQTVFARTSYSGIAKNGKSGQHAYRLLANEHISLVEKTGYTGFIRCVKDNYK"
     gene            3988..4569
                     /locus_tag="ACZPB4_09220"
     CDS             3988..4569
                     /locus_tag="ACZPB4_09220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HIR1098430.1"
                     /translation="MISRQGEKGPEWKYDLLPVYGIYLLNFSLPEFPSWRTDVVLANE
                     QTGRIRLKQIYVSFERFDLRYEECVTPLEKTIYVLKNMNLFDMSPLKEKEAHFRRLLD
                     VANLGALTPQERAIYDENLKIYRDWKATMEYAVENAEAKGEVRGSRLITLRTALNLKR
                     IGLDPSVIAQCTGLSLEEINDLENLIRKEEIKC"
     gene            4792..5079
                     /locus_tag="ACZPB4_09225"
     CDS             4792..5079
                     /locus_tag="ACZPB4_09225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009016913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030527 - structural constituent of
                     chromatin [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HIR1098431.1"
                     /translation="MNRRELVKTLADKLSVTQAEAMRFVQAWEETTTEALESDGSLML
                     LGFGTFSAWEQTERIGRNPKNGVAYMIRARKSVKFKPGKLLLKQLNASSSK"
     gene            5122..5679
                     /locus_tag="ACZPB4_09230"
     CDS             5122..5679
                     /locus_tag="ACZPB4_09230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3575 domain-containing protein"
                     /protein_id="HIR1098432.1"
                     /translation="MKRILFLVLLLVATTGVYGQKFAVKSNLLYDATATINLGVEVGL
                     AKKWSLDLSGNYNGWKFGDEARMKHWLVQPEARYWLCEKFNGHFFGLHAHYADYNVGG
                     LKFLSKNMENHRYQGNLYGAGLSYGYQWLLSDRWSMEAVLGIGWAHLDYDKYPCATCG
                     TVLKSDTKDYFGVTKAAISIIYFIK"
     gene            5688..7172
                     /locus_tag="ACZPB4_09235"
     CDS             5688..7172
                     /locus_tag="ACZPB4_09235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3868 domain-containing protein"
                     /protein_id="HIR1098433.1"
                     /translation="MNKKINAYMMAAMMAVVSPAIMGQTASDGVKVICNDVVQKGDSV
                     YIDAVVTVSSDAVKSRSYLELTPVLESASQKEGLPSILVNGRIRQKVYNREVALDNLN
                     DVPHYTILKAGKEDQVVSYKTAVPFEDWMKDARVVLDPNLCGCGKEEAGSPLLIADKI
                     RRRPDKRYEVQPTFSYITPMAETEKHRAEVGTAFLDFQVGKYQILPDFRNNAVELAKI
                     NNTIRTVTEDKNVKPTGIVLKGYASPEGSYASNKKLADNRVKALRDYIRQKNDFKADF
                     FTMSSEPEDWVGFKEKVEADPNVPNRSEVLAIIDSSDDPDRKEAKLRALGGGAAFRYV
                     LKDIFPSLRRSEYKIDYTVREFTVDEGREIIKTRPQQLSLGEMFAVANSYEIGSDEYD
                     NVFDIAVRMFPNDPVANLNAANIAMGKGDYASAKNYLAKAGNAPEAVHAKGVLSMLTG
                     DLTEAETLLKQAQDMGVKAAAINLEELRKKIEDNAVFDSFNAVK"
     gene            7224..7604
                     /locus_tag="ACZPB4_09240"
     CDS             7224..7604
                     /locus_tag="ACZPB4_09240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098434.1"
                     /translation="MKTNINNNFFYMEQASDVVELVLPHEVDNPNSVYLYLEGDAWCA
                     YERSAYYLTQMEVPVVLKKEVIRSDYDVVLLKAFFAVNDMYLPLSPTAVLKLVADDKL
                     QFQIRDRVEGFSEWKENELKKLSA"
     gene            complement(7685..8344)
                     /locus_tag="ACZPB4_09245"
     CDS             complement(7685..8344)
                     /locus_tag="ACZPB4_09245"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004788 - thiamine diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HIR1098435.1"
                     /translation="MGDNMESLEGGCVIVANGRFPSAELPLRLLKEAKTIIACDGAVK
                     TLYEKGIHPDAIVGDLDSIPAGLRERYADRIHHVEDQEINDLTKSVRFAHTQGYREVL
                     ILGATGLREDHTLGNISLLMDYAHLFKRVEMLSDYGLFTPILETTTFASYPGQQISIF
                     VLYPEGEISTEGLRWPIRRRKLTSWWQGTLNEALGDQFTVTLSPDCRVIIYREASHTK
                     E"
     gene            complement(8362..8949)
                     /gene="pnuC"
                     /locus_tag="ACZPB4_09250"
     CDS             complement(8362..8949)
                     /gene="pnuC"
                     /locus_tag="ACZPB4_09250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012056059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015663 - nicotinamide mononucleotide
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015890 - nicotinamide mononucleotide
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HIR1098436.1"
                     /translation="MVWLEYFGVITGLLYLFLEIKQHKAMWVVGFLTSLVYVFVFLSA
                     KIYADMGLQTYYVGISIYGFYQWTRKKHEIHTENDSLPSDCILYTHLSLPLFVGIIGT
                     LAVVFAILWYLLHQFTDSPIPVGDAFTTSVGIVATWMLARRIIEHWIFWVIVNLVSVY
                     LYYLRGLYPTMLLYFCYATLAIVGYYNWRKKGEEF"
     gene            complement(8970..11168)
                     /locus_tag="ACZPB4_09255"
     CDS             complement(8970..11168)
                     /locus_tag="ACZPB4_09255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012056060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HIR1098437.1"
                     /translation="MKNVLVILAGSLLATTVKAQMPSPVDSLKISKDVSLDEVVITAT
                     KVGKETPVAYSDISKQELSSRNNGQGIPFLISQSPSVIMTSDAGTGIGYSGFRIRGTD
                     ANRINITINGVPVNDSESHTVFWANMADIASSVESIQIQRGAGTSTNGAAAFGATVAM
                     QTEKPSLKPYGEYSVSAGSFGTLKHTVKGGTGLLYDHFAFDVRYSNIRSDGFIDRASA
                     RMSSYYASAAFYADNTLIKFQAFGNSEKTYQAWNGVPSYLLDTDRSYNPCGEYEEDGV
                     KKFYNNQTDNYWQHNYHLMASQRIGDFWNMNLTLHYTDGNGYYEDYKSKAKFSSYKLP
                     EYIDPEGNTVKKTDLVRRKWLDNYFYGAVYSANYQHDNTRLTLGTAVNNYVGDHFGRV
                     MWTKSANVLPQPDYEYYRNTGKKLDYNAYAKLTQRLSPLFTGYLDLQYRGIHYTIKGN
                     DDKAEEELDIHKNWNFFNPKAGINFHNNGHNAFVSFSVANREPNRDNFTEAGPEERPT
                     HETLYDYEAGYSFGNNRFRVGANLYFMDYNNQLILTGKISEIGEALTSNIKDSYRMGI
                     ELTGGVQITSWLNWNANVTLSQNKIKHFVEYVDNWDTGVQEINDLGTTNIAFSPDLIA
                     NSMFDFAYKGFIASFNSQVVGRQYIDNSSSKDRSIDPYFINSLRIGYAFQPKFMKEIT
                     LDVTINNLFNEKYETNAWVYSYIENDTRKKDDGYFTQAGTNAMARITFKF"
     regulatory      complement(11211..11321)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            11559..12026
                     /gene="rimP"
                     /locus_tag="ACZPB4_09260"
     CDS             11559..12026
                     /gene="rimP"
                     /locus_tag="ACZPB4_09260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042274 - ribosomal small subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly cofactor RimP"
                     /protein_id="HIR1098438.1"
                     /translation="MIEKKVVSQLIEEKLASSSNYLVDVVIKPGNLIVVEIDNDEAVS
                     IDDCAELSRYLEEHLDRDVEDYELEVGSAGITSPFKVLRQYVKNIGNEVEMLLKNGSK
                     LTGVLKSADENGVVVSVEKKVKPEGAKRKVTVVEDESYTFDEIKYTKYLIRFK"
     gene            12031..13296
                     /gene="nusA"
                     /locus_tag="ACZPB4_09265"
     CDS             12031..13296
                     /gene="nusA"
                     /locus_tag="ACZPB4_09265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusA"
                     /protein_id="HIR1098439.1"
                     /translation="MAKKEETISMIDTLAEFKELKNIDKDTMISVLEDSFRNVIAKMF
                     GTDENYDVIINPEKGDFEIWRNRTVVADDELEDENLQLTLTEARKIDADCEVGEEVTD
                     EVHFADFGRRAILNLRQTLASKILELQKDSLYAKYKDKIGHIIAAEVYQVWKKEILLL
                     DDDGNELLLPKSEQIPTDFYRKGETVRAIVQRVDNYNNNPKILLSRTDKVFLQRLFEL
                     EVPEINDGLITIKAIARIPGERAKVAVESYDDRIDPVGACVGMKGSRIHGIVRELRNE
                     NIDVINYTSNLSLFIQRALSPAKISSIRVNEEEKKAEVYLRPEEVSLAIGKGGLNIKL
                     ACMLTEYTIDVFRDIEGADEEDIYLDEFSDEIDSWVIDALKNIGCYTAKSVLAMDRNE
                     IIERADLEEQTVDDLLAILSAEFEDEGNE"
     gene            13317..16238
                     /gene="infB"
                     /locus_tag="ACZPB4_09270"
     CDS             13317..16238
                     /gene="infB"
                     /locus_tag="ACZPB4_09270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HIR1098440.1"
                     /translation="MPIKLIQVQRKLNVGINTVVEFLHRNGFSVEDNPNTRISDEQYA
                     LLVKEFGKDLPEKDRNFAADRMRKEVPSVKEEKTAEIKTVIPEEFRPKIVMKGHIDLD
                     GGQHKKQQEEPKAKEEPKVKEEPKVKEEPKVKEAPAAPAAQAPVKPAQPAQAPTEKKE
                     EKVIVVEVEKEKTVEKQPVVAEPKVESVKPEQEVEKTEEKDDNLFRLNSVKLESKIKV
                     TGKIDLDALNQSTRPKKKTKEEKRKERDEKQKFNNNRPGNNSNGPGAPHKSPNSPTLI
                     KPNAPAKPGEEGDAKKKRKRIKKDRVDVNNTPGTNYPRPNRDDRPNNDRKPRLKKPVK
                     AEVSEEDVQKQIKETLARLTNKNNKNNKGAKYRRDKRDAAVKREHELMEQEELESKVL
                     KLTEFVTANDLANMMDVSVTEVIGTCMSIGLMVSINQRLDAETINIVAEEFGYKTEYV
                     SADVVEAINADEEDDNEEDWVARPPIVTVMGHVDHGKTSLLDNIRSANVIAGEAGGIT
                     QHIGAYNVKLQNGRRITFLDTPGHEAFTAMRARGAKVTDIAIIIVAADDNVMPQTIEA
                     INHASAAGVPIVFAINKIDKPHANPEKIKEELANMNYLVEDWGGKYQSQEISAKKGIG
                     VEELLEKVLLEADLLDLKANPKKRAVGSIIESSLDKGRGYVSTILVENGTLKMGDIVL
                     AGTHQGRIKAMFNERNQRVEKAGPSEPVLILGLNGAPQAGDTFNVLETEQEAREIANR
                     REQLQRELGLRTQKMLTLDDIGRRIAVGNFQELNVIVKGDVDGSVEALSDSLIRLSTE
                     EIQVNVIHKAVGQISESDVVLAAASNAIIIGFQVRPSLQARRNAEKEGVEIRLYSIIY
                     DAIEEVKSAMEGMLSPEIKEEITAYVEVQQVFKITKVGTVAGCMVKEGKIKRTNKIRL
                     IRDGIVIYAGELGSLKRFKDDAKEVVAGLDCGLNITNFNDIQVGDMIEAYEETEIKKT
                     L"
     gene            16241..16732
                     /locus_tag="ACZPB4_09275"
     CDS             16241..16732
                     /locus_tag="ACZPB4_09275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HIR1098441.1"
                     /translation="MNWLDITLLCLAGIGFVKGLFDGIIKQVVSLIALVIAIFFCGKA
                     AAWLKGYILALGWFLEEGVTILSYIAGFILIMGVFILAGELVTKVVGATPLSVINHLF
                     GGFFGLLVVLVFTSLLLNALEFVDRGSVLIHRQSKIESRFYYSVKQIVPTIFPHNLFS
                     LGE"
     gene            16763..18208
                     /gene="sufB"
                     /locus_tag="ACZPB4_09280"
     CDS             16763..18208
                     /gene="sufB"
                     /locus_tag="ACZPB4_09280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007655268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HIR1098442.1"
                     /translation="MQDSNHIINEVTSGDYKYGFVTDIDTEVIHRGLDEETVRIISAK
                     KNEPEWLLEFRLKAFRHWQTLEMPTWPHLNIPPIDYQDIIYYAAPKKKEGPKSLDEVD
                     PELLKTFDKLGIPLEEQKHLSGMAVDAVMDSVSVKTTFKENLAEKGIIFCSFSEAVQH
                     HPDLVQKYLGSVVGYRDNFFAALNSAVFSDGSFVYIPKGVRCPMELSTYFRINAANTG
                     QFERTLIVADDEAYVSYLEGCTAPMRDENQLHAAIVEIVANERAEVKYSTVQNWYPGD
                     KEGKGGIYNFVTKRGLCKGEGSKISWTQVETGSAITWKYPSCILAGDNSVGEFYSVAV
                     TNNYQQADTGTKMIHLGKNTKSTIVSKGISAGHSQNSYRGLVKVSARAEGARNHSQCD
                     SLLLSSTCGAHTFPYADIQNETAIVEHEATTSKISEEQLFYCQQRGISVEEAVGLIVN
                     GYAREVMNKLPMEFAVEAQKLLTISLEGSVG"
     gene            18251..19006
                     /gene="sufC"
                     /locus_tag="ACZPB4_09285"
     CDS             18251..19006
                     /gene="sufC"
                     /locus_tag="ACZPB4_09285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010801824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HIR1098443.1"
                     /translation="MLEVKNLHANVNGKEILKGINLSVKAGEVHAIMGPNGSGKSTLS
                     SVLVGNPAFEVTEGEVIFNGKNLLDLSPEDRSREGIFLSFQYPVEIPGVSMVNFMRAA
                     LNEHRKYNGLEPVSATDFLKLMREKRAIVELDNKLASRSVNEGFSGGEKKRNEIFQMA
                     MLEPKLAILDETDSGLDIDALRIVAHGVNQLRTPENAAIVITHYQRLLDYIKPDVVHV
                     LYKGRIVKTAGPELALELEEKGYDWIKKEMGDE"
     gene            18999..20351
                     /gene="sufD"
                     /locus_tag="ACZPB4_09290"
     CDS             18999..20351
                     /gene="sufD"
                     /locus_tag="ACZPB4_09290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HIR1098444.1"
                     /translation="MSNMKAEQQYIDLFAQCEDLVCRHSTPVMNALRAEALANFERLG
                     FPSTRSEDYKYTDVAQAFAPDYGLNINRVAIPVNPYDVFRCDVPNLSTSLYFVVNDTF
                     YDKELPKAHLPEGVYAGGLKAFTEQYPEIASKYYGKAAPSSKDGIIALNTMLAQDGFV
                     VYVPKNVVVERPIQLVNIFRSDVDTMANRRVLVIMEPHSEAKLLVCDHSIDDVKFLAT
                     QVVEIFAEEGARFDYYDLEESSVSTTRFSSVHVRQAASANVLVNGITLTNGLTRNNYY
                     VELNGEYAESTLCGMSVLDKEQQMDTYSHITHAVPNCTSNELFKNVLNDHAVGVFSGR
                     ILVKEDAQKTAAYQTNRNLCATREARMYSKPQLEIYADDVKCSHGMTTGQLDENALFY
                     MQSRGIPRDEARMLLSVAFTSDVIDHVRLEALKDRLHKLVEKRFRGELAKCAGCRICK
                     "
     gene            20464..21300
                     /locus_tag="ACZPB4_09295"
     CDS             20464..21300
                     /locus_tag="ACZPB4_09295"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIR1098445.1"
                     /translation="MQLTHIALWTNHLERLRDFYVKYFNGKSNEKYVNSKKGFASYFV
                     SFESGPALEIMQRQDITEAYDKDHIGLAHLAFHADKKEQVDQMIERFRMDGYTIAGET
                     RVSGDGYYEGVIRDPDGNIVEIVANGEPEIQVALFPPYELLLEADPDREKVEAYLKDS
                     DCFIATVRNSVAGVIVVRKEEGRKAEIMNLAVADIFRRRGIARKLLRHVSNKWAPAQD
                     VELLRICTGTSAAGPMMLYQQEGFDLVAVDRDYFVRNYAEPIWENGIQCRHQLILEKR
                     LK"
     gene            complement(21401..23248)
                     /locus_tag="ACZPB4_09300"
     CDS             complement(21401..23248)
                     /locus_tag="ACZPB4_09300"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HIR1098446.1"
                     /translation="MNRHLFLSLLLALFASSTLSADNLRIEPTFWWSGMKNPELQLMV
                     YGKDIAGYLPSVKYPGVQLKSSVALESPNYLLIYLDVENAKPGRFDITFTKDKKSFNY
                     SYELKARKPNADRIKGFDSSDVLYLIMPDRFANGDPSNDQIPMRTSYKVDRNSPNARH
                     GGDLAGIEQHLDYIEDLGVTAIWLNPVLENDMEGGSYHGYATTDYYRVDPRFGTNEDY
                     VRLIEKTHERGMRVVMDMIFNHCGSDHPWMKDIPSHDWFNNLDNYVQTNHDKEAYFDP
                     YVSDYDKETMLNGWFVPSMPDLNQKNPHVAKYLIQNSIWWIEYCGVDGIRQDTYPYAD
                     VDMMRNWCTEVMNEYPEYNIVGEAWMNYTIGSAYWQKGSRLNFGQDTELKSVMDFRLM
                     GIASKAFHEETGYSGGLHTIFEHMCYDYVYPDIYNVLRFLENHDTDRFLPSMPKSVDD
                     LYAFKQGVTFLLTIPGIPQLYYGQELLMNGTKEKGDGYIRLDVPGGWPGDKVNQFEAS
                     GRSEVQNDAWNFLRTLLKWRKGNAVIAKGKMKHFMVNQGVYVYERSLDGRSVLILMNG
                     SDKEVNLPLARYAEVLRGKTSGKEILTGKEIPLGDELSLAPKGIFVLEM"
     gene            23422..26589
                     /locus_tag="ACZPB4_09305"
     CDS             23422..26589
                     /locus_tag="ACZPB4_09305"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HIR1098447.1"
                     /translation="MIKSLIVSMFLTGCVSSLSAQQSFWKEDFSAGKLPDGWMIVDST
                     KSAKCEWIVTDQPYPGSFQFEQQAPPIASTSRGYHMQFRPGVVTGEEITKWNQREEYP
                     NGYFQTSAIDCAGKNDVVLKFQHLFRWNNWFTGKRAGLWVGVSNDGVNWKEYNVMDKI
                     PAATQLHAPVNEEINISEVAANQKTVYLRFFWRDIFSWYWMVDDIELTEPFAHDLALE
                     KVTSHQETGNTFTKEDVLKVKLKNVGSQPVDEDFTVTASLNNGQKLTATVTASGHPIA
                     KQEEYEVAFPATDLTQMGSYKIEFAIQYPKDERSSNNILKANLFAARMNLGKLTKFNK
                     ISNTEYEFVSGYAKVKLMFYRDDIFRIWLAPDGEYTNPAANSIVVDYGVKNPRVSMAD
                     NGSYYKFTTSQCVVRVYKNPIRFAMYDKNNRAVIYEEAEPLAFGLKTTQTMRRSGDED
                     FYGCGMQQGNFSYAGKEADIEVTGWDEDQSSNPAPFYMSTKGYGVFRNTFAPGHYAFN
                     GTEMLDKNYDDGFKLMGFTSQLTHNENRFDAFYFYGPSLKDLLNDYTDITGKPFMPAM
                     WMLTMGDADCYNKGEQRTGWPQSTPDVISQVADKYVEYDMPRGWILPNDGYGCGYVKL
                     DSVVTELGKRGFHTGLWTENGVDKIAYEVGKCGTRLCKLDVAWVGEGYEFALNGCKSA
                     FEGIESNTNERGFVWAVCGWAGTQRYSTVWSGDQVSNWDYIRYHIPTITGAGLSAMNA
                     ATSDVDGIFGGSPKTYTRDLQWKVFTPIFMTMSGWADADRQPWVYGHPYTDINRKFLK
                     LKMRLNPYAYTYCHEAHMTGVPMARAMVLEFPGDVVTRDTTTQYQFMSGEWMMVAPVY
                     TRKNVRDSIYFPAGEWYDYWTGKKYEGGKWLDKYEAKLDICPVFIRQGAIIPMYPDMN
                     YVGEKPADVLTLDLYPYGNTSFNLYEDDGLTRDYKKGEFARTLISVSSPKGEKGTITV
                     DIAKAKGDYKGRYQERTYLLDVRSESSPSNVTVAEKPLSAISPEAFNAGQEGWYFDAS
                     DRMGRVKVRTNRLSTNQDQKIVIGF"
     gene            26614..>27539
                     /locus_tag="ACZPB4_09310"
     CDS             26614..>27539
                     /locus_tag="ACZPB4_09310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HIR1098448.1"
                     /translation="MKTQLTLCISGTLLLVGMSGCEKTPERPMNVVYILADDLGYGDV
                     GCYGQQIIKTPNIDRMAKEGMLFTQHYAGCTVSAPSRCSLMTGLHTGHTQVRGNREIT
                     PEGQQPMREDTYTLGKLMKSAGYTTGIFGKWGLGNPGSVSIPNKMGFDEFYGYNCQRQ
                     SHSFYPDHLWHNEEKVLFPENENNACKTYSQDLIHEQALKFIRDHKEQPFFAMLTYTL
                     PHAELNLPHDSIYKMYENSFEETPYIGKFDKVYGGYNTSEKPLASFAAMVSRLDKYVG
                     DVMAELKELGLDKNTIVIFTSDNGPHHEGGADP"
BASE COUNT         7609 a         5387 c         7156 g         7387 t
ORIGIN      
        1 atctgctcat actcgttttc atactttttt gatcgttaca aagttaatat caagcgagtt
       61 gtcctcaggt atgaaaaact gtgcaaatta ctgaaataga atctgttgtg ccgtttcttg
      121 ttcctgttat atcagtaacg atatgggaac tgaagtcttt cgcagctttt atcggacctc
      181 ctttttcagc ttatgcagta ttatgagtta aacacctaac cacttaatag actgcatttt
      241 tgctgtatta tcatcaacct tgctttttct ttctgcgttt actttaaaat ataatgggac
      301 taatgaagct attagagtct tattgattca gctaagtgct aaaatagaat ataaagggat
      361 ctataataag aataacaatg acttgattaa cgatcaattc tcattaataa atgtggaagg
      421 cttaaatgct agttcgcaag tcgctatttt taatacctct tctgtggaaa atggagtttt
      481 cgaggcattg acttaccctt cggaagataa gccgacgacg ttctatacgt atgaaattag
      541 tgacgcgaat aaaaatattc tattgagtgt acaacaaaat gggtcagaga taaaaagttt
      601 ttcttttcct gccaataagt ttataaaggg caactattac gagataaaag gtctatatga
      661 accttctacg gaaatagaat ggattttaga agaggttggg aacgagaatg tcgctcttga
      721 cccttttgaa taaatagaaa gtatgtctaa tggctaaaaa atcaagatga tgaaacaata
      781 tattatgttt ttattaggat tattaatcct aagcgcttgc acaaacgatg agtatctggc
      841 tcaaagaaca gaagtagaag aaggtatccc tacggtggtg aaattatctg tgacgattcc
      901 tatgagcggt aagattgaga caaaggcttt ttctgatagt ggtgttgctg atttatatgt
      961 gttttccttt aaaaaggata atgatgagtt tataaccgct caaaagtata cggaactttc
     1021 cggatctacc atatctttct ctaccttgtc cggagaacaa cggatttttg cgataggaaa
     1081 tgtggattat gatatgtttc cgggactttc ggaaagatta gagtcgtggt tgggaaataa
     1141 tcatccttca aaatctgatt tgacttctct tttagcggaa gttggaggag ataaagcggt
     1201 ccagtttgcg aatactacct cattggtaag tggattatgg aataatgagg atgatacaaa
     1261 agattattgt actgtcaaag tggatgggac attggttgag aaaggcaaaa tttacttaaa
     1321 gcgagtagcg gctaaggtga cttttaaaat tgaagtggca gatggccggg aatttaaatt
     1381 gaaaagttac caagtttgtg aagttcctaa aaaggtaaat gtatgggaag gttctacttc
     1441 agaagagatt gtttcttatt caactcagga attgacaatc tcaagagatg aaggattttt
     1501 tactttttat atgcctgaaa atatagctaa tggaaaagag ggttgtaatt ctgcggatga
     1561 tcgtgaaaaa ttatcgaaag ggtctttaag aaattcaccc ccggaaggaa gagtgttcac
     1621 atatgtcgat aagccggcta cgtacgtatt attgaaaggt tcttactacg caaaagatac
     1681 agacggaaaa gaaacgagtg cggaagttgt atattgtatt catttaggtt taggagcggg
     1741 gagtagcgat aaggttgatc ataaagattt ttcaacaaag cgtaatatga attatacata
     1801 taatattcag atagaaggag ttgaaagtat aaaaacggaa gttacagcta ccgataataa
     1861 tgtttggcgg caagaaggag atgtaacggt ttcgggagaa ggaaaatcaa ttcaattaga
     1921 cgctcatttt gaggcaagaa aaataacgtt tcataaatcg gattttaaaa ctacagattt
     1981 gagagtttac gtaaaagatc ctctgactaa tttccaatta acagaattct cggaattaaa
     2041 ggaggagtca aaaaattggg tttcttttaa atctctaaaa gatgtgcctg tagaagaaac
     2101 ctataaatat cctgatgaga agcacgtgag tgaattgctt tctgttgaag aattattgac
     2161 tgagttgaat aaatgggcaa aaggagagaa ttctcttcta gctcccacaa atgagggagc
     2221 tatcgagttt gtttgttttg tgaatgagta ttattatcaa agtataatgt ggccagagtt
     2281 tgttaataca cttgatcgtg aattctttat tatggataaa acacagaaac agacatctgg
     2341 aggaaatagt actcttactt cagatgcctc gttcgtgatt aaacaacatt ctatccagac
     2401 aatatatgat ttaaacaaag gagaagatta taacgcttgg gggattgaga ctataaacga
     2461 gaccggatta ttaaatacaa caactaatcc aagtaaaatc aaggatattg cttatggccg
     2521 tttaaatcta ccagacttta gtggtaaagg ttggagcact tttttggatt attcaaaaga
     2581 aagtaactct aatcagatga aggacgatta taaaaatgcg tattatgctt gtttgcaacg
     2641 aaatcgagat gagaatgggg atggagtgat agactcaaaa gagaaaaaat ggtatttggc
     2701 ctcttctggg caatatatat ctttatggct ggggcgctcg tctttatctg cggaatcttc
     2761 actttttaat atagatgatt gggtaaaaga gggttttgct aaaaatattc cagctaaata
     2821 tcattatata ccaagtaata atgatggcaa agttgtgttt tgggcagaag aaggaattac
     2881 aataggtaat gatgatagtc atacgacagg aaagatacga aactatcggt gtatacgaga
     2941 tttgaatatg aaaggaatgg atgagaataa tttagataga aaaaaggcac ctgaaacgct
     3001 tttcaaaata tcttctgttg atcctaaggc acttactgtt acgtttgact atttgaatgc
     3061 aaattcatta aaaccggctc cttccatgaa tgaattggac ccacataatg aacgtgataa
     3121 tgatataaac agggtttata agtctttttg tattgttagg ggaagtgtgt caagcaatca
     3181 agttggtgga acatggaagg caaaaacaaa tcttacgaat ccatgtaatc gtataatgaa
     3241 tgagcatggt tggcgtatgc cgaatcaagc ggaattgtct gttatttatc tagttggaac
     3301 tgatgcgagt gcatatggat catataagaa aaatgaattt aatggcttaa aaggccaaac
     3361 cgtttttgct cgtacttcat atagtggcat tgctaaaaat ggaaaatccg gacaacatgc
     3421 ttatcggttg cttgctaacg aacatatttc tttagtggag aagactggat atactggatt
     3481 tatccgttgt gtaaaagata attacaaata gaattaaaat ccagaaaaag tagaatcaat
     3541 tgctgcgaaa aacggtttta atatatatct aattgtagag acacagcatc atgctgtgtc
     3601 tctctctatt taactgaaat caatctaaca ctttgtatcc ttaactcccg gagaatcctt
     3661 ttttccgccc aatttacggc tagcctccaa atacgcaaga aaaaaatagg cttacggctg
     3721 gggtataaca gtgtaagaat gcccattcac aaccgcttat gatgcccaat tgtacagttg
     3781 gtgttatgaa tggcttattt tatctagacg agatttttta ttcggaaaat agtccttacc
     3841 tttacggcat agatacgttg tcaagtatta atcaatcaaa acccatacga actatggaac
     3901 attacgtgaa tatcatgttg gatagtggct tcaaggccgc cttgtacgac gagcgtgagg
     3961 tgatgcagtt tttactatat ttgccgtatg atctcccgtc aaggagagaa gggcccggag
     4021 tggaaatacg acctgctccc ggtatatgga atctaccttt tgaacttcag ccttcccgag
     4081 ttcccttcat ggcgaacgga cgtggttctg gcaaatgagc aaacagggcg gattcggctg
     4141 aaacagatct atgtctcttt cgaacgattc gatttgcgtt acgaggagtg cgttactccg
     4201 ttagaaaaaa caatttatgt actgaagaat atgaacctgt ttgatatgtc tcccttaaag
     4261 gagaaagagg cccacttccg ccgtttgctg gacgtggcga acttgggtgc cctcaccccg
     4321 caggagcgtg ccatctacga cgagaacctg aagatctacc gggattggaa ggcgacgatg
     4381 gagtatgcgg tggagaatgc tgaggcaaaa ggtgaggtga gaggtagccg cttgattact
     4441 ttacgtaccg ctttgaactt aaaaagaatc ggcttggatc cctctgtgat cgcccaatgt
     4501 acggggcttt ccttggagga gataaacgat ctggagaatc tcattcgcaa ggaagagatt
     4561 aagtgttaga tgtggatgat atggtataac agctaagggg caggcttaca caagtctgcc
     4621 ccttgctgtc tttataaagt gtcggtgttc ctatcacctt ctttgaaatg aataggtgtt
     4681 cttatcaatc aaggatagtt ggtaggttta ccctttaaag ttgaaactca cacctatcgt
     4741 gctaagaaat gttataatct atttttgtga tgcaaattaa aagtgaaagg gatgaatagg
     4801 agagaactcg tgaaaacatt ggctgataaa ttgtcggtta cgcaagcgga ggcgatgcgc
     4861 tttgttcaag cttgggaaga gactacgaca gaggctttgg aaagtgatgg ttctttgatg
     4921 ctattgggct ttgggacgtt ctccgcttgg gaacaaaccg aacggatcgg cagaaatcct
     4981 aagaatgggg tggcttatat gataagagct cgtaaaagcg tgaagtttaa gcccggtaaa
     5041 ttattactta aacagttgaa tgcgagctcg tcgaagtgaa ggcattcacg tatgtataat
     5101 aaaaacgaaa aaatattcga tatgaagaga attcttttcc tagtcctgct cttggtagct
     5161 acgacaggcg tttacggcca gaagttcgcg gtgaagtcga acttgctcta tgatgcgact
     5221 gctacgatca acttgggcgt agaggttggc ttggctaaaa aatggtcgct ggatctatcc
     5281 ggcaactata atggatggaa gtttggtgat gaggctcgta tgaaacattg gctggtacaa
     5341 ccagaagctc gttattggtt gtgtgagaag tttaatggac atttcttcgg cttgcatgcg
     5401 cattatgcgg attacaatgt tggaggccta aagttcttga gcaagaatat ggagaatcac
     5461 cgttatcaag gtaatttgta tggcgctgga ctctcttatg gttatcagtg gttgttaagc
     5521 gatcggtgga gcatggaagc cgtgttgggt attggttggg cgcatctgga ttatgataaa
     5581 tatccttgtg ccacttgcgg aaccgtattg aaaagtgata cgaaagatta tttcggggtt
     5641 acgaaagccg ctatttctat tatttacttt attaaatgac ccaagcgatg aacaagaaga
     5701 taaatgcata tatgatggcg gctatgatgg ccgtcgtgtc tccggcaatc atgggacaga
     5761 ctgcctcgga tggggttaaa gtgatttgta acgacgtggt acagaagggc gactcggtat
     5821 atatcgatgc cgtggtgacg gtaagtagcg atgcggtgaa atcccgtagc tatttggaac
     5881 tgacccccgt cttggaatcg gcttcgcaaa aagaggggct tccttctatt ttggtgaacg
     5941 gacgtatccg ccagaaagta tataatcgtg aggtcgcctt ggataatttg aacgacgtac
     6001 ctcattatac tatcttgaaa gccgggaagg aagatcaagt ggtaagttat aaaaccgccg
     6061 tgccttttga ggattggatg aaagacgcac gtgtcgtgtt agacccgaat ctatgcggtt
     6121 gcggtaagga agaggccggt agtccgttat tgatcgcgga caagattcgt cgtcgtccgg
     6181 ataagcgcta tgaggttcag cctacattct cttatatcac gccgatggca gagacggaga
     6241 agcatcgtgc ggaagttggt acggctttct tggacttcca agtgggtaaa tatcagattc
     6301 ttcctgattt ccgtaataat gcggtggagt tggcgaagat caataatacg atccgtaccg
     6361 ttacagagga taagaacgtg aaaccgacag gtatcgtact gaaaggatat gcctcaccgg
     6421 aaggctctta cgctagtaat aagaaattgg cggataatcg tgtcaaagcg ttacgtgact
     6481 atatccgcca gaagaatgac ttcaaggctg attttttcac gatgagctcg gaaccggaag
     6541 attgggtcgg ttttaaggaa aaggtagagg ccgatccgaa tgtgccgaat cgtagcgagg
     6601 tattggcgat tatcgatagc tcggatgatc cggatcgcaa ggaggctaag ttacgtgcct
     6661 tgggtggtgg cgccgctttc cgttatgtgt tgaaagatat tttcccttcg ttacgtcgtt
     6721 cggaatataa gattgattat acggtgcgtg agtttacggt ggatgagggg cgtgagatca
     6781 tcaagactcg tccgcaacag ctaagtttag gggagatgtt cgcggtggct aacagctatg
     6841 agatcggtag tgacgaatat gataatgtat ttgatattgc tgtccgtatg ttcccgaatg
     6901 atccggtagc gaatcttaac gctgcgaata tcgctatggg caagggtgat tatgcttccg
     6961 ctaagaacta tttggcgaag gcggggaacg ctccggaggc ggttcacgca aaaggagtgt
     7021 taagtatgtt gaccggtgat ttgacagaag cggagaccct attgaagcag gctcaggata
     7081 tgggtgtaaa ggccgcggcg ataaatttag aggaattgcg caagaaaata gaggataatg
     7141 cggtatttga tagtttcaac gctgtaaaat gatagctatt cctccctagg tatagggcag
     7201 aaggcactta atttgtaaat gtcatgaaga caaatattaa taataatttc ttttatatgg
     7261 aacaagcatc agatgtagta gagttggttc tgcctcatga ggtagataat ccaaacagtg
     7321 tctatctgta tctggaagga gatgcttggt gcgcatacga acgttcagcc tattatctga
     7381 ctcagatgga ggtaccggtt gtattaaaga aagaagtgat ccgcagcgac tatgatgtgg
     7441 tcttactgaa agcttttttc gccgtgaatg atatgtattt gccgctttct cccacggctg
     7501 tgctgaagtt ggttgccgac gataagctac agttccagat aagggatagg gtagaaggtt
     7561 tttccgaatg gaaagagaat gagttaaaaa aattatctgc ttgataagga agcgaacgct
     7621 tcttatttaa gcatgtaaag ttgaggggtg taagggtcct ggaaagtagt gatacttttc
     7681 aggactattc ttttgtatgg gatgcctccc tgtaaatgat tacccggcaa tccggggaga
     7741 gagtgacagt gaattggtct cccaaagcct cgttgagagt tccttgccac catgaggtga
     7801 gctttcgtcg gcgaatgggc caacggagtc cttccgtact aatctcccct tcgggataaa
     7861 gaacgaaaat ggagatttgt tgtcccggat aagaagcgaa ggttgttgtt tctaagatag
     7921 gagtgaaaag gccatagtcg gataacatct ccacccgctt gaataagtgg gcatagtcca
     7981 taagaaggga tatatttccc aatgtatgat cctcacgcaa tccggtagca cctaatataa
     8041 gaacttctcg atagccttgg gtatgggcga aacggacgga tttggtgagg tcgttgatct
     8101 cttggtcctc tacatgatgg attcggtctg cgtagcgttc gcgcaggccg gcgggtatgc
     8161 tgtccaagtc tcctacgata gcgtccggat gaataccctt ttcataaagt gtctttacgg
     8221 ctccatcaca agcgataatc gttttcgctt cctttaataa tctcaagggt aactcagcgg
     8281 aaggaaatct cccattcgct acgatcacac atcctccttc cagactttcc atattatctc
     8341 ccataattca aaattcataa ttcaaaactc ttcccctttc ttccgccaat tgtaatagcc
     8401 tactatggct agtgtcgcat agcaaaaata gagtagcatc gtcggataca agccccgaag
     8461 gtaataaaga tatacggaaa cgaggtttac gattacccaa aaaatccaat gctcgataat
     8521 tcgccttgcc agcatccaag tagcgacaat gcctaccgac gtggtgaacg catcgcctac
     8581 ggggatggga gagtccgtga attgatgaag gagataccat aagatggcga atacaacggc
     8641 caatgttccg ataatcccca cgaaaagcgg aaggctcaga tgggtgtata ggatacagtc
     8701 ggagggaaga ctgtcgtttt ccgtgtgtat ctcatgtttc ttccgggtcc attgatagaa
     8761 accgtatatg ctgattccta cgtaataggt ttgcaatccc atgtccgcat agatcttagc
     8821 ggacaggaag acaaatacat acacgaggga ggtgaggaat cccaccaccc acatggcctt
     8881 atgttgttta atctctagaa agagatagag tagaccggtt attactccga agtattctag
     8941 ccaaaccatt ttagtaattg aaaattaagt tagaatttga aggtgatcct ggccatggcg
     9001 ttcgtgccgg cttgggtgaa ataaccgtca tcctttttac gtgtgtcgtt ttcgatataa
     9061 gagtataccc atgcgttggt ctcgtacttc tcgttgaaga ggttgttgat agtcacgtct
     9121 agggttattt ctttcatgaa cttaggctgg aaggcgtaac cgatacgtag gctattgata
     9181 aagtagggat cgatggaacg atccttgctg cttgaattgt ctatgtattg gcggcctact
     9241 acttgcgagt tgaaactagc gataaatcct ttgtaagcga aatcgaacat gctgtttgcg
     9301 attaggtctg gggagaaagc gatattcgtt gtacctagat cgttgatctc ttgtactccg
     9361 gtatcccagt tatccacgta ttccacgaaa tgcttgattt tattttggct gagggttacg
     9421 ttcgcgttcc aattcagcca agaggtgatt tgtacacctc cggtaagctc gatgcccatt
     9481 cggtagctat cctttatatt ggaagtgagg gcctcaccga tctcgctgat cttgccggtc
     9541 aggatcaatt ggttgttgta atccatgaaa tagagattgg ctccaacccg gaaacggttg
     9601 ttaccaaaac tataaccggc ctcgtaatca tataaggtct cgtgggtagg acgttcttcg
     9661 gggcctgcct ccgtgaaatt gtcacggttc ggttcccggt ttgcgacgga gaaagagacg
     9721 aatgcgttat ggccgttgtt atggaagttt ataccggctt tcgggttgaa gaagttccag
     9781 ttcttatgaa tgtccagctc ttcctcggct ttgtcatcgt ttcccttaat ggtgtaatgg
     9841 atcccacggt attgtaagtc cagatagccg gtgaaaagag gggaaagacg ttgggtcaat
     9901 tttgcgtatg cgttgtagtc taatttctta ccggtattgc ggtaatattc gtaatccggt
     9961 tgtggcaaga cgtttgcgct tttggtccac attacccggc caaaatggtc gcctacgtag
    10021 ttgttgacgg cggttcccag cgtaaggcgg gtgttgtcat gttgatagtt cgcgctataa
    10081 acggctccat agaaataatt gtcgagccat ttacggcgca caaggtccgt cttttttacg
    10141 gtattaccct ccggatcgat atattccggt agtttataac tgctgaattt ggctttcgat
    10201 ttataatcct cgtaatatcc gttaccatcg gtgtaatgaa gggtcaggtt catattccag
    10261 aaatctccga tacgctggct ggccattaaa tggtagttgt gttgccaata attatccgtc
    10321 tgattgttat aaaacttctt cactccatct tcctcatatt ctccgcatgg attatagcta
    10381 cgatctgtgt caagtaaata agacggaaca ccgttccatg cttgataggt cttctcgctg
    10441 ttcccgaagg cttggaattt aatcaatgta ttatcggcat agaaagcggc ggaggcatag
    10501 taagagctca tacgggcgga ggcacgatcg ataaagccgt cgctacggat attggagtag
    10561 cggacgtcga aagcgaaatg atcgtaaagt aatccggtac cgccttttac cgtatgcttc
    10621 agcgtaccga aagaacctgc tgatacggaa tattcgccgt aaggctttaa ggacggtttc
    10681 tcggtctgca tggcgaccgt agcgccaaaa gccgcggctc cgttcgtaga ggttccggca
    10741 cctcgttgga tctggatcga ttctaccgag gaggctatat cggccatatt agcccagaat
    10801 acggtatgag actcggagtc attaaccggt acgccattga tcgtgatatt gatacggttc
    10861 gcgtctgtac cccggatacg aaaaccggag taacctatac ctgttccggc atccgaggtc
    10921 atgataacag acggggattg ggagataagg aatgggatac cttgcccgtt gttccggctg
    10981 cttagctctt gtttggagat gtcgctataa gctaccgggg tttctttccc gactttggta
    11041 gcggtaataa ctacttcatc caaagatacg tcttttgaga ttttcaagga gtcgaccgga
    11101 ctgggcattt gtgccttgac ggttgtagcc agtaaggagc cggccaagat aaccaataca
    11161 tttttcatct tttcatcttt ttgctttaaa actaaataga tgaatagaaa ggatcggaga
    11221 agcatgaatc cctacgacag cattacctgt acaggttcta tgggtatgat ctcagcccgc
    11281 tcctttcgtg aaggattttg cgagcacccc ttcgtattcg gcagcaaaga taggcataaa
    11341 agtgttaata aatattactg tcaatagtaa atcggatttc tatagatatt aattctgatt
    11401 actatggata gtaatccggt ttgtgtcgta ttaatttttt ctgtaaaaag atgaggatat
    11461 tttgagaact cattgatttt ttgtatattt gcgggcgatt aagtgaagtt gaggaggggg
    11521 cgggtagtcc ccttcttttg ttcttaacag atatgtgtat gatagaaaag aaagtggtaa
    11581 gccaattaat agaggaaaaa ctagcctctt caagcaatta tttagtagac gtggtgatta
    11641 aaccgggaaa cctgatagtc gttgaaattg ataacgatga agcggtaagc attgatgatt
    11701 gcgccgagtt gagccggtat ttggaggagc atctggatcg tgacgtcgag gattatgagc
    11761 tggaggttgg ctccgccggc attacttctc ctttcaaggt acttcgccaa tacgtcaaga
    11821 acatcggaaa cgaggtggag atgctgttga aaaacggctc gaagctgacc ggtgtgttga
    11881 aatctgccga cgagaacggt gtggttgtct ctgtcgagaa gaaggtgaaa ccggaaggcg
    11941 ctaagcggaa ggtgactgtg gtggaggatg agtcgtatac atttgatgaa ataaaatata
    12001 caaaatactt aataagattc aagtaagatt atggccaaga aagaggaaac aatcagtatg
    12061 attgacaccc ttgcggagtt caaggagttg aagaatatcg ataaagatac gatgattagc
    12121 gttttggaag attcgttccg taacgtgatc gccaagatgt ttggcacgga tgagaactat
    12181 gacgtgatta tcaaccctga gaaaggtgat ttcgagatat ggagaaaccg tacggttgtg
    12241 gctgatgatg aattggagga tgagaacttg cagcttacgt tgacggaggc ccgtaaaatc
    12301 gatgccgact gtgaggtggg cgaggaagtg accgacgagg tgcatttcgc agacttcgga
    12361 cgccgtgcga tcttaaactt gcgccaaact ttggcttcaa agatacttga attgcagaaa
    12421 gacagcttgt acgctaagta taaggataaa atcggccaca tcatcgccgc tgaggtttat
    12481 caggtgtgga agaaagaaat cctgttgctg gatgacgatg gtaatgagtt gctactgccg
    12541 aaatccgagc aaatcccgac cgatttctat cgtaagggag agaccgtacg tgcgatcgtt
    12601 caacgtgtgg ataactataa taacaacccg aagatccttc tttcccgtac ggataaggtc
    12661 ttcttgcaac ggttgtttga gttggaggtt ccggagatta atgacggctt gattacgatc
    12721 aaggcgatcg cccgcatccc gggagagcgt gccaaggtgg ctgtcgagtc atacgatgac
    12781 cgtattgatc cggtaggcgc ttgcgtaggt atgaaaggct ctcgtatcca cggaatcgtt
    12841 cgcgagttga gaaacgagaa cattgatgtg attaattaca cctcaaatct ctctttgttt
    12901 atccagcgtg ccttaagccc ggctaagatc tcttctatcc gtgtgaatga ggaggaaaag
    12961 aaagctgagg tttatctacg tccggaggag gtttctttag cgatcggtaa gggcggtctg
    13021 aatattaagt tggcttgtat gttgactgag tatacgattg acgtattccg tgatatcgaa
    13081 ggagcggacg aggaggatat ctacttggat gagttctccg acgagatcga cagctgggtg
    13141 atcgacgcac tgaagaatat aggatgctat acggcgaaga gtgtccttgc tatggaccgc
    13201 aatgagatta ttgaacgtgc cgatctggaa gaacagaccg tggacgatct tttagctatc
    13261 ttatctgcgg aatttgaaga tgaaggtaac gaataagtat tacgacaaag ttagatatgc
    13321 ctataaaatt aattcaagta cagagaaaat tgaacgtggg aatcaacacg gtggttgagt
    13381 tcctgcaccg gaatgggttc tcggttgagg ataatcccaa cacgaggatc agtgatgaac
    13441 agtatgcttt gctcgtaaaa gagtttggaa aggatctgcc agagaaagat cgtaattttg
    13501 cggcggatcg tatgcggaaa gaggttcctt ctgtgaaaga agagaagacc gcggaaataa
    13561 agacagtgat accggaagaa ttcagaccta agatcgtaat gaagggtcat atcgatttgg
    13621 atggtggaca acataaaaaa cagcaggaag agccgaaggc taaagaggag ccgaaggtga
    13681 aagaagagcc taaggtaaag gaagagccga aagtgaagga agcgcctgcc gctcccgctg
    13741 ctcaagctcc tgttaaaccc gcgcagcctg cgcaggctcc cacggagaaa aaagaagaaa
    13801 aagttatagt agtggaagtg gaaaaagaaa aaaccgtaga gaagcaaccg gttgttgcgg
    13861 aacctaaggt ggaaagtgtg aaaccggaac aggaagtaga gaagaccgag gaaaaggatg
    13921 ataatctttt ccgtttgaac tcggttaaat tggagtcaaa gatcaaggta accggtaaga
    13981 ttgacttgga tgcgcttaac caatcgactc gtccgaaaaa gaaaacgaag gaggagaagc
    14041 ggaaagagcg tgatgagaag caaaagttta ataacaatcg gccgggtaat aatagcaacg
    14101 gtccgggcgc tcctcataag agtccgaatt cgccgacttt gattaaaccg aacgctcctg
    14161 ctaaaccggg tgaggaaggt gacgctaaga agaagcgtaa acgtatcaag aaagatcggg
    14221 tagacgtgaa taatacgccg ggtacgaatt atccgcgccc gaatcgtgac gatcgtccga
    14281 ataacgaccg taagcctcgc ttgaagaagc cggtgaaagc ggaagttagt gaagaggatg
    14341 ttcaaaagca gatcaaggag actttggctc gcttgaccaa caagaataat aagaataata
    14401 agggggctaa ataccgtcgt gataaacgtg acgccgctgt gaaacgtgag cacgagttga
    14461 tggaacagga agaactggaa agcaaggtat tgaagctgac cgagttcgtt acggccaacg
    14521 acttggcgaa catgatggac gtatctgtaa cggaggttat tggtacttgc atgagcatcg
    14581 gccttatggt ttcgatcaat cagcgcctgg atgcggagac gatcaatatt gtggctgagg
    14641 agttcggtta taagactgaa tatgtaagcg cggatgttgt cgaggcgatc aacgctgatg
    14701 aggaagatga taacgaggag gattgggtag cccgtccgcc tatcgtaacg gtgatgggac
    14761 acgttgacca tggtaagact tctttattgg ataatatccg tagcgcgaac gtaatcgccg
    14821 gtgaggccgg tggtatcacg cagcatatcg gagcctacaa cgtgaagttg cagaatggcc
    14881 gccgtatcac gttcttggat actccgggtc atgaggcgtt taccgctatg cgtgcccgtg
    14941 gcgcaaaggt gacggatatc gcgattatta tcgtggccgc tgatgataac gtgatgcctc
    15001 agacgatcga ggcgattaat cacgcttcgg ctgccggtgt tcctattgtt ttcgctatta
    15061 ataaaatcga taagccacat gctaatcctg agaagatcaa ggaggagttg gcgaatatga
    15121 attacttggt ggaagactgg gggggtaagt accagagtca ggagatctcc gctaagaaag
    15181 gtatcggtgt cgaggagttg ttggagaagg tcttgttgga ggccgacctg ttggatttga
    15241 aagcgaatcc gaaaaaacgt gcggttggtt ctatcatcga gtcttctttg gacaagggac
    15301 gtggctatgt atctaccata ttggtggaga acggtacgtt gaagatggga gatatcgttt
    15361 tggcgggaac tcatcaagga cgtatcaagg cgatgttcaa cgagcgtaat caacgggtgg
    15421 agaaggccgg tccttccgag ccggtattga tcctcggttt gaatggtgct cctcaggccg
    15481 gtgatacatt taatgtattg gagactgagc aagaggcgcg tgagatagct aaccgtcgtg
    15541 agcaattgca gcgtgagtta ggtcttcgta cgcagaagat gcttactttg gatgatatcg
    15601 gacgtcgtat cgccgtgggt aacttccaag agttgaacgt gatcgtgaag ggtgatgtgg
    15661 atggttccgt agaggctttg tccgactcct tgatccgttt gtctaccgag gagattcagg
    15721 taaacgtaat tcacaaggcg gttggccaga tttccgagtc ggatgtggtt ttggcagcgg
    15781 cttcgaacgc tatcattatc ggattccaag ttcgtccgtc tttgcaagca cgtagaaacg
    15841 ccgagaagga aggtgtggag atccgtttgt attctatcat ctacgatgcg atcgaggagg
    15901 tgaagagcgc tatggaaggc atgctttctc cggagatcaa ggaggagatt accgcttatg
    15961 tggaagttca gcaggtattc aagatcacca aggtcggtac ggttgccgga tgtatggtta
    16021 aggaaggcaa gatcaaacgt acgaacaaga tccgtttgat acgtgacggt atcgttatct
    16081 atgccggtga gctaggttct ttgaaacgtt tcaaggacga tgcgaaagag gtcgtggctg
    16141 gcttggattg cggtttgaat attacgaact tcaacgatat ccaagtgggc gatatgatcg
    16201 aggcttacga agagacagaa ataaagaaga cgttataacg atgaactggt tggacattac
    16261 attgctatgt ctggcaggga taggatttgt gaaaggcctg tttgatggaa tcatcaaaca
    16321 ggttgtttcg cttatagccc tagtgatcgc gatctttttc tgcgggaaag cggcggcttg
    16381 gctgaaagga tatatcttgg cgttgggttg gtttctggaa gaaggggtta cgatcttgag
    16441 ttatatagcg ggttttatct tgattatggg ggtatttatc ctagcgggtg aactggttac
    16501 caaggtggta ggggcgacac cgttgagcgt tatcaaccat ttgtttgggg gttttttcgg
    16561 gttgctggtc gttttggtct ttaccagttt gctgttgaat gcgctggagt tcgtggatcg
    16621 cggatcggtc ttgattcatc gccaatcgaa gatagaatct cgtttttatt atagcgtgaa
    16681 gcaaatagta ccaacaattt tcccacataa tttgttttca ttaggagaat gaagggcttt
    16741 tatcaatggt taatttataa ttatgcagga ttcaaatcat atcattaatg aggtaacgag
    16801 cggagattat aaatatggct tcgttaccga tattgatacg gaggtgatcc atcgtggatt
    16861 agacgaggag acggtccgta ttatctctgc caagaagaac gagccggaat ggttactcga
    16921 gttccgtttg aaggcttttc gccattggca gacgttggag atgcctacat ggcctcactt
    16981 gaatatcccg ccgatcgatt atcaggacat tatctattat gccgccccta agaaaaaaga
    17041 gggaccaaag agcttggatg aggtagatcc tgagttgttg aaaacattcg ataaactggg
    17101 tattcctttg gaagaacaga agcatttaag cggaatggcg gtagacgccg tgatggatag
    17161 tgtttccgtg aagactactt tcaaggagaa tctcgcggag aaggggatta ttttctgttc
    17221 gttcagcgag gctgtacaac atcatccgga cttggtgcag aagtatttgg gcagcgtggt
    17281 tggttatcgt gataatttct ttgccgcctt gaattcggcc gtgttctcgg acggttcgtt
    17341 tgtttatata ccgaagggcg tacgttgccc gatggagttg agtacgtatt tccgtatcaa
    17401 tgccgctaat accggacagt tcgagcgtac cttgattgtc gcagacgatg aggcgtatgt
    17461 aagttatctg gaaggatgta cggcgccgat gcgtgacgag aaccaattgc atgccgctat
    17521 cgtggagatc gtggcgaacg agcgtgccga ggtgaagtat tctaccgtac agaattggta
    17581 tccgggtgat aaggaaggta aaggcggtat ctataacttc gtgacgaaac gaggtttgtg
    17641 caaaggtgag ggtagcaaga tctcttggac gcaagtagag accggttcgg cgatcacttg
    17701 gaaatatccg agctgtatct tggcgggtga taactcggta ggtgagtttt actcggttgc
    17761 cgtgaccaat aattaccaac aggccgatac gggtacgaag atgattcatc tgggtaagaa
    17821 tacgaaaagt acgatcgtat ccaagggtat ctctgccggt catagccaga atagctatcg
    17881 gggattggtg aaggtgtccg cccgtgcgga aggcgcccga aaccatagcc aatgcgatag
    17941 tttgttacta agctctactt gtggagctca tacgttccct tacgctgata ttcagaatga
    18001 gacggcgatc gtggagcatg aggctacgac gagtaagatc agtgaggagc aattgttcta
    18061 ctgccagcaa cggggtatct cggtagaaga ggctgttggt ttgatcgtga atggatatgc
    18121 ccgcgaggta atgaataagt taccgatgga gtttgctgtc gaggctcaga aattactaac
    18181 gatctcgctg gaaggcagcg taggatagaa taattttcaa ttttcaactt tcaattttca
    18241 attagaaaag atgttagagg ttaagaattt acatgccaac gtaaatggca aagagatatt
    18301 gaaaggtatc aacctgtcgg tgaaagcggg tgaggtacat gctatcatgg gaccgaacgg
    18361 ttctggaaaa agtacgttaa gtagtgtatt agtaggtaat cccgcttttg aggtaacgga
    18421 aggagaggtt atcttcaacg gtaagaatct gctggatctt tctcccgagg atcgtagccg
    18481 tgagggtatt ttcttgagct tccaatatcc ggtcgagatc ccgggagtta gtatggtgaa
    18541 ctttatgcgt gcggcgttga acgagcaccg taaatataac ggtctggaac cggtttcggc
    18601 tacggacttc ttgaaattga tgcgtgagaa acgtgcgatc gtcgagctgg ataataaact
    18661 ggccagccgt agcgtgaacg aaggtttctc cggtggagag aaaaaacgga acgagatctt
    18721 ccagatggcg atgctggagc cgaaattggc gatcttggat gagacggata gtggtttgga
    18781 tatcgatgcc ttgcgtatcg tggcgcatgg cgtgaaccag ttgaggactc cggagaatgc
    18841 cgctatcgta atcacgcact atcagcgtct gctggattac atcaagccgg atgtggttca
    18901 tgtgctttac aaaggccgta tcgtgaagac cgccggtccg gaattggcct tggaactgga
    18961 agagaaaggt tacgactgga tcaagaaaga gatgggagat gagtaatatg aaggccgagc
    19021 aacaatatat cgatcttttc gcccaatgtg aggatctggt atgtcgtcat agtacgccgg
    19081 tgatgaatgc cctcagggct gaggccttgg cgaactttga gcgactcgga ttcccctcca
    19141 cgagaagcga ggattataaa tatacggatg tagcccaagc gttcgctccg gattacggtt
    19201 tgaatatcaa ccgggtcgct atcccggtga atccttatga cgtgttccgt tgtgacgtac
    19261 cgaacctgag cacatcgtta tactttgtag tgaacgatac gttttacgat aaggaattgc
    19321 caaaagcgca tttgccggaa ggcgtgtatg ctggagggtt gaaggctttt acggagcaat
    19381 atccggagat cgcttccaag tattacggaa aggcggcacc gagtagcaag gatggtatta
    19441 tcgcattgaa tacgatgtta gcccaagatg gtttcgtggt gtatgtaccg aaaaatgtcg
    19501 tggttgagcg tcctatccaa ttggtgaata ttttccgtag cgatgtggat acgatggcga
    19561 accgtcgtgt tctggtgatt atggaacctc attcggaagc gaagctattg gtttgcgatc
    19621 atagtatcga tgacgtgaaa ttcttggcga ctcaagtggt tgagattttc gcagaggaag
    19681 gcgctcgctt cgattattat gatttggagg aaagcagtgt gtccacgacc cgtttctcct
    19741 ccgtacacgt aaggcaggcg gcctcggcca atgtcttggt aaacggtatt acgttgacga
    19801 atggcttgac tcgcaacaat tattacgtgg aactgaatgg cgagtatgcc gagtctacct
    19861 tatgcggtat gtccgttctg gacaaggagc aacagatgga tacctatagc catattaccc
    19921 atgcggttcc gaattgtacc agcaacgagt tgttcaagaa tgtactgaat gatcatgccg
    19981 taggtgtctt cagcggacgt atcttggtga aagaggatgc ccagaagacc gccgcttacc
    20041 agacgaaccg taatctgtgc gctactcgtg aggcccgtat gtacagcaag ccgcaactgg
    20101 agatttatgc ggacgacgta aaatgctcgc acggtatgac gaccggtcag ttagatgaga
    20161 acgctttgtt ctatatgcaa agccgcggta tcccgcgtga cgaggcccgt atgctattga
    20221 gcgtggcttt cacttccgac gtgatcgacc atgtacgctt ggaggcgttg aaagaccgtt
    20281 tgcataaact ggtggagaaa cgtttccgcg gtgagctggc caaatgcgcc ggttgccgga
    20341 tttgtaaata attgcgaata agaggaaaac tataatcagg catggattat cccgacgata
    20401 atgtagggaa ccatgtctga tttttttata tctttggcag tgacaaatta aaacctccaa
    20461 cttatgcagt taacacacat cgccttatgg acgaatcatc tggaacgttt acgggatttc
    20521 tatgtaaagt attttaatgg taagagtaat gagaaatatg tgaattcgaa aaaaggattc
    20581 gcctcctatt tcgtctcttt cgagagtggc cccgccttgg agatcatgca acggcaagat
    20641 attactgagg cttacgacaa ggatcatatc ggcttggctc atctggcctt tcatgcggat
    20701 aagaaggagc aagtggatca aatgatcgaa cgtttccgga tggatggata cacgatcgcc
    20761 ggtgagaccc gcgtttccgg ggatggttac tatgagggcg tgatccgaga tcctgacgga
    20821 aatatagtag agatcgtcgc taacggggag ccggagatac aagtagcttt atttcctcct
    20881 tatgagttac tgctggaagc cgatccggat cgggagaaag tcgaggctta cctaaaggat
    20941 tcggattgct ttatcgctac ggtacgaaat tccgttgccg gcgtgatcgt ggttcgcaag
    21001 gaggagggtc gcaaggcgga gatcatgaat cttgccgtgg cggatatctt ccgtcggcga
    21061 ggaatcgccc ggaaactatt acggcatgta tctaataaat gggctccggc tcaagatgtc
    21121 gagcttttgc gtatttgcac cggaacctca gccgccggcc cgatgatgct ttatcaacag
    21181 gaaggcttcg acttggttgc cgtagatcgc gattatttcg tacggaacta tgccgagcct
    21241 atctgggaga acggcattca atgcaggcat caattgattc ttgaaaagcg attaaaatag
    21301 tatatatgaa aagaaaatcg ggaggtttaa ggcctcccga tttaattatt agtaatctat
    21361 gaataggtcc tcgaatgaaa aatcatcggg gctaatggca tcacatttcc agtacgaaga
    21421 tccctttcgg tgccaaggat aattcgtctc ccaatggaat ctcctttccg gttaatatct
    21481 cttttccgga ggttttacct cgcaatactt ccgcatagcg ggccaacggg aggttcacct
    21541 ccttgtcgct gccattcatc aagatcaata cgctccggcc atccagactg cgctcgtaaa
    21601 catagacacc ttggttcacc atgaaatgct tcatcttgcc cttagcgatg acagcgttgc
    21661 ccttgcgcca tttcaataaa gtgcggagga aattccacgc gtcattttgt acctcgctgc
    21721 gaccggatgc ctcgaattga ttcaccttgt cgccgggcca gccaccggga acatccagac
    21781 ggatatatcc gtctcccttc tccttggtgc cgttcatcag caactcctgc ccgtaataga
    21841 gctggggaat accggggatc gtcaacaaga atgtcacccc ttgcttgaac gcgtacaaat
    21901 catcgacaga cttaggcatg gagggaagaa aacgatccgt atcatggttc tccaagaaac
    21961 gcaatacgtt atagatatcg ggatatacat aatcatagca catatgctcg aagatcgtgt
    22021 gcaagcctcc ggaatacccg gtctcctcat ggaacgcctt gctcgcgata cccatcaagc
    22081 ggaaatccat taccgatttc agctcggtat cctgcccgaa gttcaaccgg ctgcctttct
    22141 gccaataagc ggaaccgatc gtgtagttca tccacgcctc gcctacgatg ttatactccg
    22201 gatactcgtt catgacctcc gtgcaccaat tccgcatcat gtccacgtcg gcatacggat
    22261 acgtatcttg acggatacca tccacgccgc aatactcgat ccaccagata gagttctgga
    22321 taaggtattt ggctacatgt gggttctttt ggttcaagtc cggcatgctc gggacaaacc
    22381 aaccgttcag catcgtctcc ttatcataat ccgacacgta aggatcgaaa taagcctctt
    22441 tatcgtggtt ggtctgcacg tagttatcga gattattaaa ccagtcgtgg ctagggatat
    22501 ctttcatcca aggatgatcg cttccacaat ggttgaagat catatccatt acgacacgca
    22561 tgccccgctc gtgcgtcttc tcgatcaagc ggacgtaatc ctcgttcgtg ccgaagcgtg
    22621 ggtctacccg ataataatcc gtcgtggcat atccgtgata agagcctccc tccatgtcat
    22681 tctccaatac cgggttcagc cagatagcgg taacgcccag atcctcgata taatccaaat
    22741 gctgctcgat accggccaag tcacccccat gacgggcgtt cgggctgtta cggtctacct
    22801 tataagaggt acgcatcggg atttgatcgt tcgagggatc tccgtttgcg aaacgatccg
    22861 gcatgatgag ataaagcacg tcggaagagt caaacccctt gatccgatcg gcgttcggtt
    22921 tacgggcctt caactcatac gagtaattga aactcttttt gtccttcgtg aacgtgatat
    22981 caaacctgcc gggcttggcg ttttccacgt ccagatagat caataggtaa ttcgggcttt
    23041 ccaacgctac cgagcttttc aactgtacgc cgggatattt cacgctaggg agatatccgg
    23101 cgatatcctt accgtatacc atcagctgga gttccgggtt cttcatacca ctccaccaga
    23161 aggtcggctc gattctaagg ttatcggctg aaagcgtact ggaagcgaaa agggccagta
    23221 aaaggctcaa gaataaatgt ctgttcatga tatatgttta ttgatttata tgacaaggtt
    23281 gtacatacgc gaagatagaa ggattccatt gataataaca cgctttcgcc cggcgaaaag
    23341 ggaataaaaa tcacgcgaac gtttgcgaac cctcgtaaat taagactatc tttactgcct
    23401 aaatctaatc aactaattca aatgataaaa agtctaattg tatccatgtt tctgacaggt
    23461 tgcgtttcct ccctgtccgc acaacaaagt ttttggaaag aagatttctc cgccgggaaa
    23521 ttacccgacg gctggatgat tgtcgattca acgaaatcgg caaagtgtga atggattgta
    23581 accgatcagc cttatcccgg ctctttccag ttcgagcaac aagcacctcc catcgcatct
    23641 acgagccgtg gctatcatat gcaattccgg ccgggcgtag tcaccgggga ggagatcacg
    23701 aagtggaatc aacgggagga atacccgaac ggctatttcc agaccagcgc tatcgattgc
    23761 gcgggaaaga acgatgtggt attgaaattc cagcacctgt ttcgttggaa taattggttc
    23821 accggaaaac gtgccggcct ttgggtaggc gtcagcaacg acggggtgaa ttggaaagag
    23881 tataacgtga tggataagat ccccgccgct acccagcttc atgccccggt gaacgaggag
    23941 atcaacatca gcgaggtagc cgcgaatcag aaaaccgtct acttgcgttt cttctggcgg
    24001 gatatcttct cttggtattg gatggtcgat gatattgagc tgacagagcc tttcgcgcat
    24061 gacttggcct tggagaaagt gacctcacac caagaaaccg ggaatacgtt cacgaaggaa
    24121 gacgtgttga aagtgaagct gaagaacgtt ggctcccagc ccgtagacga ggatttcacg
    24181 gtaaccgcct ctttaaacaa cggtcagaaa ctaaccgcca cggtaaccgc ctccgggcat
    24241 ccgatcgcta aacaagagga atatgaggta gctttccctg ctaccgacct aacccagatg
    24301 ggctcctata aaatagagtt cgctatccaa tacccgaagg atgagcgttc gtcaaacaac
    24361 atattaaaag cgaacctgtt cgccgcccgt atgaacttgg gtaagttgac gaagttcaat
    24421 aagatcagca acacggaata tgagttcgtc tccgggtacg ctaaggttaa gttgatgttt
    24481 taccgggatg atatcttccg tatctggttg gcaccggatg gggagtatac caatccggcg
    24541 gcaaactcga tcgttgtaga ttatggggta aagaacccga gagtctccat ggccgacaac
    24601 ggcagctatt ataagttcac gacttcccaa tgtgtcgtac gtgtctataa gaaccctatt
    24661 cgtttcgcca tgtatgacaa gaataaccgt gccgtgatct acgaggaggc cgaaccactt
    24721 gccttcggac taaaaacgac ccaaacgatg cgccgtagcg gtgatgagga tttctacggt
    24781 tgcggtatgc aacaaggtaa tttctcatac gctgggaagg aagcggatat cgaggtgacc
    24841 ggttgggatg aggatcaatc ctctaacccg gctcccttct atatgtccac gaaaggatat
    24901 ggcgtattcc gcaatacgtt tgccccggga cattatgcct tcaacggcac ggagatgttg
    24961 gacaagaact atgatgatgg ctttaagctg atgggcttca ccagtcagtt gacgcataac
    25021 gagaatcgct ttgacgcatt ctacttctac ggcccttcct tgaaagacct attgaacgac
    25081 tatacggata tcaccggaaa accttttatg ccggcgatgt ggatgcttac gatgggagat
    25141 gccgactgct ataacaaagg ggaacagcgc accggatggc ctcaatccac cccggacgta
    25201 atcagccaag ttgctgataa atatgtggaa tatgatatgc cccgtggctg gatcttgccg
    25261 aacgatggct atggttgcgg ctatgtgaaa ttggattctg ttgtgacgga attaggtaaa
    25321 cgaggcttcc atacgggctt gtggacagag aatggtgtgg ataagatcgc ctacgaggtt
    25381 ggtaaatgtg gtacccgcct gtgtaaattg gatgtggctt gggttggaga aggctatgag
    25441 tttgccttga acggctgtaa atccgcattc gaggggatcg agagcaatac gaacgaacga
    25501 ggcttcgtat gggctgtttg cggttgggcc ggaactcagc ggtattctac ggtatggagc
    25561 ggtgaccaag taagcaactg ggattatatc cgttaccata tcccgacgat cacgggtgcc
    25621 ggcctttccg ctatgaacgc cgctactagc gatgtggacg gtatcttcgg cggttccccg
    25681 aaaacctata cccgcgactt gcaatggaag gtcttcaccc cgatctttat gaccatgagt
    25741 ggctgggcag atgccgaccg tcagccttgg gtatatgggc atccgtacac ggatatcaac
    25801 cgtaaattct taaagctgaa gatgcgtctg aacccgtacg cctataccta ttgccatgag
    25861 gcgcatatga ccggtgtacc gatggctcgt gcgatggtat tggaattccc gggcgacgtg
    25921 gttacccgtg atacgactac ccaataccag ttcatgagtg gtgagtggat gatggttgcc
    25981 cccgtatata cccggaagaa cgtacgcgac agtatctact tccctgccgg agaatggtac
    26041 gactattgga ccggaaagaa atacgagggt ggcaagtggt tggataaata tgaggctaaa
    26101 ctggatattt gcccggtatt tatccgtcaa ggcgccatta tcccgatgta tccggatatg
    26161 aattatgtag gcgagaaacc tgcggatgtc ttgaccttgg acttatatcc ctacggaaac
    26221 acctctttca atttatatga ggatgacggt ctcacccgtg attataagaa aggcgagttt
    26281 gcccgtacct taatctctgt ttcctcccca aaaggtgaga aaggaacgat caccgtggat
    26341 atagcgaaag cgaaaggaga ttataaagga cgttaccaag agcgtactta cctattggat
    26401 gtccgctcag aatccagccc gtcaaacgta accgtagccg aaaagcccct atctgccatc
    26461 tcccccgaag cgttcaatgc cggacaagaa ggctggtact tcgatgcctc ggatcgtatg
    26521 ggaagggtta aggtacggac gaaccgcttg tctacgaatc aggatcagaa gattgtaatt
    26581 ggtttctaac acttctattt attttaaagg tatatgaaaa cacaattgac tttatgtata
    26641 tccgggacat tgctgcttgt cggaatgtcc ggttgcgaaa aaactccgga gcgtcctatg
    26701 aatgttgtgt atatcttagc ggatgattta ggatatggcg atgtgggttg ttatggccag
    26761 cagattatca agacgcccaa tatcgatcgg atggcgaagg agggaatgtt gtttacgcag
    26821 cattatgccg gatgtacggt gagtgcccct tcccgttgct ccttgatgac cggattgcat
    26881 acgggacata cgcaagtccg gggaaaccgg gagatcacgc ccgaaggcca acagccgatg
    26941 cgggaagata cctatacgtt gggtaaatta atgaaatcgg ctggttatac gaccggtatc
    27001 tttggtaaat ggggattggg aaatccgggc tctgtctcca ttcccaataa gatgggcttc
    27061 gatgagtttt atgggtataa ttgccaacgg cagtcgcatt ccttctatcc ggatcattta
    27121 tggcataatg aggagaaggt tctttttcct gaaaacgaga acaatgcttg caagacatat
    27181 tcacaagatt tgattcatga gcaagcattg aagttcatcc gggatcataa ggagcaacca
    27241 ttctttgcga tgcttactta tacgctgcct catgcggaat tgaatcttcc gcatgattct
    27301 atttataaga tgtacgagaa ctcattcgag gagactcctt atattggtaa gtttgataaa
    27361 gtgtatggcg gttataacac ctcggagaag cccttggcct cctttgccgc catggtctcc
    27421 cggttggata aatacgtggg ggatgtaatg gctgaattga aagagttggg tttggataag
    27481 aatacgatcg tgatttttac cagcgataac ggcccgcatc atgagggtgg agctgatcc
//
LOCUS       DBMDTB010000049        27527 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_631_length_27527_cov_12.567709, whole genome shotgun sequence.
ACCESSION   DBMDTB010000049 DBMDTB010000000
VERSION     DBMDTB010000049.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 27527)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 27527)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27527
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_631_length_27527_cov_12.567709"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..938)
                     /locus_tag="ACZPB4_09315"
     CDS             complement(<1..938)
                     /locus_tag="ACZPB4_09315"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HIR1098449.1"
                     /translation="MKVLKFGGTSVGSVNSILSVKKIVEAIEEPVIVVVSALGGITDK
                     LLATSTMASKGDLAYEKELSEIIARHLDVIEGVIEDKEVRMDVQKKVMALLDELSNIF
                     KGVYLINDLSAKTSDTIVSYGERLSSLIVSNVIKDAKLFDSRKYIKTVKQFNKHIVDF
                     DLTNKLIKETFSPLPKVSLVPGFISSSTETGEVTNLGRGGSDYTASILATALDANTLE
                     IWTDVDGFMTADPRVISSAYVIDRLTFTEAMELCNFGAKVIYPPTIYPVYHKNIPIRI
                     LNTFNPTAPGTYISKERVKEEGKAIIKGISSINDTC"
     gene            complement(1221..2186)
                     /locus_tag="ACZPB4_09320"
     CDS             complement(1221..2186)
                     /locus_tag="ACZPB4_09320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HIR1098450.1"
                     /translation="MMNQEKLKGHLLILAANILFAINMPVSKYLLPEHVQPEALTSMR
                     MSFACVMFWITSLFVPYEKVPLKDLGLLCLCALCGVGLNQGLFIWGLNTTSPVDASII
                     ATAVPIFVMILAALILKEPITRMKTFGVLLGICGAISLILQSTQGSNQASSLGGNLLI
                     TVSGFMYSIYLVVSKPLTLKYSSVTMMKWMFLFSTLITLPFAIESIWNTPAFHKEVFD
                     GQELGAIFFVLFGATFIPYLLIPLALKRIRPTTVSMYNYIQPIVASFIAVFIGQDSFS
                     VTKLVSAALVFSGVYLVTQSKSRADLEQQNSQSFSKNACNMKNNA"
     gene            complement(2342..3205)
                     /locus_tag="ACZPB4_09325"
     CDS             complement(2342..3205)
                     /locus_tag="ACZPB4_09325"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HIR1098451.1"
                     /translation="MGSLKEIKVRIASIRSTQKITAAMKMVSSAKFHHAQTQTEHTLT
                     YANKLSAILNGLLSAECDLDSPYTEQRKVSKVAIAVFASSTGLCGTFNANIWKELSAT
                     IQTYKNQQIEVGLYPIGKKIADELHKAGYSFDTDFVTIGEKPSYESAVSLANRLMELF
                     VTGKADRVELLYHHFKNMATQVVTHKTYLPLSLSDTEAAETATDYILEPSAEELRNRL
                     FPKLLNLTIYTILLDTSTAEHAARMMAMQTANDNANDLIQQLTLQYNKTRQQAITNEL
                     LDIMGGAAVSS"
     gene            complement(3193..4770)
                     /gene="atpA"
                     /locus_tag="ACZPB4_09330"
     CDS             complement(3193..4770)
                     /gene="atpA"
                     /locus_tag="ACZPB4_09330"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045259 - proton-transporting ATP
                     synthase complex [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HIR1098452.1"
                     /translation="MTEQIKVSEVSSILRQQLEGIHTSIKLEEVGTVLQVSDGVARIY
                     GLDNAEANELLQFDNGMEAIVMNLEEDNVGAVLLGPTDRIKEGDTVKRTGRIASIDVS
                     EGMIGRVIDPLGNPIDGKGEILGETCEMPLERKAPGVIFRQPVNEPLQTGIKAVDAMI
                     PIGRGQRELIIGDRQTGKTSIAIDTIINQRSNYEAGNPVYCIYVAIGQKGSTVAALVN
                     TLQEKGAMDYTIVVSATASDPAAMQYFAPFAGAAIGEYFRDSGRHALVVYDDLSKQAV
                     AYREVSLILRRPSGREAYPGDIFYLHSRLLERAAKIINQPEVAREMNDLPESMRDKVK
                     GGGSLTALPIIETQAGDVSAYIPTNVISITDGQIFLETDLFNQGNRPAINVGISVSRV
                     GGNAQLKAMKKVAGTLKIDQAQFRELESFSKFGGEMDAVTAFTIDKGQKNTQLLIQPQ
                     YSPMPVEEQISILYCGTQGLLKEVPLDKVHEFEARFLQELRTSHQRDVLDVLKTGVIN
                     DEIRGILEKTAKELWVH"
     gene            complement(4783..5325)
                     /locus_tag="ACZPB4_09335"
     CDS             complement(4783..5325)
                     /locus_tag="ACZPB4_09335"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HIR1098453.1"
                     /translation="MDIGTISSRYAKALFSLAKDKEQESRVYDDMKMLADSFSMEPEL
                     RGALSNPIVSVPEKVKLLTAAGGIEVCELYSRFINLVLAHKRETLLPFIAYIYIHLYR
                     KEKKITRVRFDTAVAVDDAVKSHLQDKLRKETGCTIEFSGHVEPELIGGFRLRIGNYR
                     IDASYATQLRDIRTGLLENR"
     gene            complement(5329..5829)
                     /gene="atpF"
                     /locus_tag="ACZPB4_09340"
     CDS             complement(5329..5829)
                     /gene="atpF"
                     /locus_tag="ACZPB4_09340"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045259 - proton-transporting ATP
                     synthase complex [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HIR1098454.1"
                     /translation="MSLLTPDSGLLFWMIVSFGIVFVILSKYGFPVIVKAIEQRKAYI
                     DNSLETARQANERLAHIQAEGEKMLAEAKEKQNAVLKEAFAEKERIIEEARKKAVSEA
                     HLQIEEATRRIREEKEKAIREVRSEIADLSIAIAEKVMKEKIGRDKEQQQMIDRLLDE
                     VSFSKS"
     gene            complement(5844..6098)
                     /gene="atpE"
                     /locus_tag="ACZPB4_09345"
     CDS             complement(5844..6098)
                     /gene="atpE"
                     /locus_tag="ACZPB4_09345"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045259 - proton-transporting ATP
                     synthase complex [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HIR1098455.1"
                     /translation="MLSTILLQAAAGMGVAKMGATIGAGFAAIGAGIGIGLIGKGAVE
                     AIGRQPSAAGEIRTSMLIMGALVEGVALFAIVVCFLALFQ"
     gene            complement(6161..7210)
                     /gene="atpB"
                     /locus_tag="ACZPB4_09350"
     CDS             complement(6161..7210)
                     /gene="atpB"
                     /locus_tag="ACZPB4_09350"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045259 - proton-transporting ATP
                     synthase complex [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HIR1098456.1"
                     /translation="MMSTIKDNKYIWIAFWMWLSFLTPAKAASGEIDVQDIVFSHIQD
                     AYTWHITEWNGQEIAIPLPILVKSEERGWDLFLSSHLHQGRTHHNYYIAGEGEHAGKV
                     VEKNSAGEEVRPMDFSLTKNVCGLFLSCGLLLFIVLRTAHWYKKHPNEAPGGFIGLME
                     MAISYIQDGVIKEAIGKEYKPFSSYLLTVFFFILINNLIGIIPVFPGGANITGNIAVT
                     GVLALCTFIAVNLFATKVYWKEIFWPKAPIYLKLPLPIMPFVEFFGVFTKPFALMIRL
                     FANIMAGHTIILALTCLIFITVTMGVAVNLGMTIVSVLFCAFMNCLELLVACLQAYIF
                     TLLSANYIGLAKVRE"
     gene            complement(7188..7619)
                     /locus_tag="ACZPB4_09355"
     CDS             complement(7188..7619)
                     /locus_tag="ACZPB4_09355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098457.1"
                     /translation="MNGRLKMRLMGLITFINVAIGVSLGGLLYTIWPEHYFSWYPSIP
                     FFYWVMAMAMTFFLDRVKRKNGDVTVTMYMLVRLCKFTLAFVFLWMYAAFVGQQLKTF
                     GFTLMLFYFIYLGLETYILYLFEKKRMKREKREKDDEYNQR"
     gene            complement(7632..7865)
                     /gene="atpC"
                     /locus_tag="ACZPB4_09360"
     CDS             complement(7632..7865)
                     /gene="atpC"
                     /locus_tag="ACZPB4_09360"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045259 - proton-transporting ATP
                     synthase complex [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit epsilon"
                     /protein_id="HIR1098458.1"
                     /translation="MKLEIVSPDGILFEGETESVSFPGVAGSFDILPHHAPLIAALKA
                     GTIRFEANGKRQEQTIQSGFVEVKDDILSVCVE"
     gene            complement(7871..9388)
                     /gene="atpD"
                     /locus_tag="ACZPB4_09365"
     CDS             complement(7871..9388)
                     /gene="atpD"
                     /locus_tag="ACZPB4_09365"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005633052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045259 - proton-transporting ATP
                     synthase complex [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HIR1098459.1"
                     /translation="MGEIKGYISQVIGPVVDIHFDYGTEETVTLPRIHDAMEISRPNG
                     KILIVEVQQHIGENTVRTVAMDTTDGLRRGMEAMSYGMPITMPTGDQVKGRLMNVTGD
                     PIDGMAQLTKDGALPIHREPPKFEDLTTTQEVLYTGIKVIDLLEPYAKGGKIGLFGGA
                     GVGKTVLIMELINNIAKKNNGFSVFAGVGERTREGNDLLREMIQSGVIRYGEEFKKSM
                     EAGNWDLSKIDYDELAKSQATLVFGQMNEPPGARSSVALSGLTIAESFRDKASEGERK
                     DILFFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGAMQERITSTKKGSITSV
                     QAVYVPADDLTDPAPATTFTHLDATTVLSRKITELGIYPAVDPLESTSRILDPLIVGK
                     EHYDTAQRVKQILQRNKELQDIISILGMEELSDEDRLTVNRARRVQRFLSQPFSVAEQ
                     FTGVPGVMVSIEDTIRGFKMIMDGETDDIPEQAFLNVGTIEDVLEKAKQLKEQAN"
     gene            9766..10497
                     /locus_tag="ACZPB4_09370"
     CDS             9766..10497
                     /locus_tag="ACZPB4_09370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HIR1098460.1"
                     /translation="MKRIIEICANSAQSCVEAEAGGATRVELCAGIPEGGTTPSYGEI
                     KTAKALTSKIDINVIIRPRGGDFLYTEAEVQSMLLDIELCKELKVHGVVFGCLTKDGD
                     IDVPLMRRLIEAAKPLSVTCHRAFDVCRDPFTALEQLIELGCDRILTSGQQSDAVKGI
                     PLIAELVKRADGRIIIMPGCGVRENNIGKIEAETGAKEFHTSARSIVYSKMEYRNENV
                     PMGSSIVSSEFETVQTDREKVKAYI"
     gene            10665..11045
                     /locus_tag="ACZPB4_09375"
     CDS             10665..11045
                     /locus_tag="ACZPB4_09375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098461.1"
                     /translation="MLNVTVNNRFGFHQRIMLMIMLVLLQFYSIGSDFFPENITTTSM
                     EIVDKEAPDVLLDFDDNASLRTVRQEQVQIRALEIDLIWDLFTILDLHELIHSLELRQ
                     CAKLPLFYNLHKAQNFVWFCSYLI"
     gene            11136..12299
                     /locus_tag="ACZPB4_09380"
     CDS             11136..12299
                     /locus_tag="ACZPB4_09380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HIR1098462.1"
                     /translation="MRIKLFSNYLPLLCLTACVWVSCSQNREKKSGKKDHTPVMRLTT
                     TTIEVPQSYVADVQAVQFVEVKPKVEGFVEAVLVDEGEHVKKGQVLFKLSSAELYEEV
                     KEAQANHKQAQAELKMAEVEVDRIKRLVEKDIISPIRLEQAMAEADVARLQVQQAKSR
                     LQRAETNFSYTTITAPFEGYVDRIPFKVGSLVTPSSLLTSLTDVSDMFAYFKINEKEY
                     LEYKRTQLSGIDQPEYNNLELILSDQSTYRYKGKVETVEGDFERGTGSIAFRARFANP
                     ERLLRHGVSGKIRMLTKMENVVLVPQQSTFEIQDFTYVYTVAEDGKVSVRSFEPLARH
                     GSYYVTQDLPDQTVIVYEGVQMITDGMTINPDMVDGATIRRQLESSNEIENNK"
     gene            12305..15463
                     /locus_tag="ACZPB4_09385"
     CDS             12305..15463
                     /locus_tag="ACZPB4_09385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0042908 - xenobiotic transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HIR1098463.1"
                     /translation="MFEIFIRRPILSGVISVVIVFLGLLAINSLPITQFPDIVPPSVT
                     VTARYTGANADVMAKTVATPLERAINGVPGMTYMTSVCTNDGMSLTTIYFKVGTDPDV
                     ASVNVQNRVTTVLDELPEEVIRAGVITEKEVNSMLMYLNIMSSDSTHTEKFVYNFADI
                     NILRELKRIDGVGFVEIMGSRDYAMRVWLNPNRLAAYNMSPQEVTEAIRSQNIEAAPG
                     KTGISSDKIPQQLQYVLQYSGKFSTPEEYGEIVLKALPDGSVLRLKDVATIEFDSEDY
                     NMISMTDGKPSASIMIKQRPGSNAREVIQQIKAKMEELKETTFAPGMEYNISYDVSRF
                     LDASISVVLKTLLEAFILVFIVVYLFLQDFRSTLIPAIAVPVSLIGTFFFMQMLGFSI
                     NMLTLFALVLAIGIVVDNAIVVVEAVHVKMHNEKLPPLKATKKAIGEIGGAIIAITLV
                     MSAVFIPVGFMDGTVGIFYRQFSLTLAVAIVISGVNALTLSPALCALLLKPVSHSKKA
                     KKGLLTRFFEGFNRRYDFLERRYRLNLRWFLNRRMLTYATLILFCLATWGMTFVLPSG
                     FIPNEDQGMIYVNVDAPPGATLERSEAALNKVQAALLPLEEVETISTLAGYSLMTETE
                     GASFGMGMINLTPWDQREQTAAELMSVYADRVAHIKDADIQFFLPPTVPGFGNASGFE
                     LRLQDKTAGTFAELDEVAKNFVAKLNADPRLTGVTSGFNPNFPQYLLRVDLAKAAKLG
                     INVNESMETLQSYVGSFYSSNFVRFGQMYKVMLQAAPEYRMNPEDLFSLYAKNKEGNM
                     VPYSNFMTMERVYGPSQITRYNLFTSAMITGEAAPGVSSGEALAAVEEIASEVLPRGY
                     DTEWSGVAKEEKESGGQTLVIFAICLAFVYLLLAAQYESLLLPLPVILSLPAGVFGSF
                     FLLYVVGLENNIYAQVALVMLIGLLGKNAILIIEVANQCRKEGISVMGAAIQGATSRL
                     RPILMTSFAFISGLIPLTIASGAGALGNRSIGTAAAGGMLIGTFVGIFLIPGLYVIFE
                     SLATYFKKRKEKEQIKEDEYVY"
     gene            15453..16895
                     /locus_tag="ACZPB4_09390"
     CDS             15453..16895
                     /locus_tag="ACZPB4_09390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0015288 - porin activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux transporter outer membrane subunit"
                     /protein_id="HIR1098464.1"
                     /translation="MCIDKMRYIMIGCALALIALAGCKTPELLMDERISLPESGEMGM
                     NDTTFVKPLSWDVFFQDTLLRGYVDVALRNNHSFQQSMERIAMSRAALQRAKGLLLPD
                     VNLNIGASVNRFGEYTMDGVGNSETNVPSLPKDKHIPDPYRDFGLSLSFQWEADIWGK
                     LTRKKQAAAARWMASVEATRFAQSMLISDLAIQYYELIGLDRRKEVLRNALASARRSH
                     ELTRQLKKEGAETQLAVDQFYARVLLIESKLLENDQLIGEKERAIACLLGVFPFEIRR
                     MGFDELRKLPVPLSEGIPANLLTLRPDVRSAEMGLVASKADVIAAKAAFYPSLVLGAS
                     GGFNAFDVGKWFHSPASLVYDLAAGITAPIFRRNEIRSMWNEAKASQRIALSQYHETA
                     LNAYTEVLDLYCASQTQTERIRLKEKESLAHQRSVVNAGEMFQLSYTGFLEVLSAEER
                     YLDSELEHIDIVTDLCRKKILLYRALGGGC"
     gene            17128..19773
                     /locus_tag="ACZPB4_09395"
     CDS             17128..19773
                     /locus_tag="ACZPB4_09395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5916 domain-containing protein"
                     /protein_id="HIR1098465.1"
                     /translation="MKYLTLLVFLGISLLCEAQQDSIVPFEKAYKRTYNIRKVSGVKP
                     TIDGKLDEDFWTKQGEWSDRFVQIIPYERAITQSPTRVKLFYDDKYIYVGVYCKDAVP
                     DKMNRFIGNRDDNSLGDLISVAFDTYHDYRAAPEFNINLGGNKTDLVVTDKLNVNLSW
                     NAVWEGRTNINRADSSWTAELRIPFSQLRYNQRSEDGVWGLHVRRIIRRNNEVQNWSM
                     IPLKNNGHVFSFGNMSGMDSVPKPRGIEFLPYVMGKYRQEPRIDGSPYQKGHSWGGNV
                     GLDAKFALSDYTLDMTINPDYGQVELDPSVMNLTAYETFYDEKRPFFLEGKHILDFAN
                     GSDMMFYTRRIGASPSYTPRGIDNVGSYAETKENVPIIGALKLTGTNKRGLTIGVIES
                     VTARSSSKVTRNGVEDVEVVEPLTNYTVARVQKNWKGNTLLGGMVTSVNRALDQPYLE
                     DFMVRNAFTAGIDFTQYFKNRLYYIDVKGMLSSLHGSAGAITALQNSVAHYYQRASSA
                     DYLGVDPTRRSLTGTGGYVKVGRKGNAKWNFSETFTWSSPGFDLNDMGYMKETDYLMN
                     ETEIMYRQTDIWKIFRYNAFTLSQKNMWNYGGTPFSNNASLRWQSMTMNRYEWDVKET
                     FAWNWLDSRLLRGGPDVRFGSYFLTSAKFNTDKAKRMMFMLKYEGDHNFEGNRFNTIS
                     PSLTFRLGNHVYLSGQLDYAWNTDEMQYVATTSPLSSSSLTPYYYVMGHMDQKTYGLT
                     LKLQVNVTPDISIQFYGAPFTSIAKYDDFKLAADTKSHTFENRFQRIDPDHLTYVDGV
                     YTIGEGAGQMPFRNPDFRFNEFRSNLVARWEYLPGSTLYFVWEHRMSNRDNWYSSGWG
                     SNLDRMWGLPATNTFMIKMNYWFNL"
     gene            20178..23315
                     /locus_tag="ACZPB4_09400"
     CDS             20178..23315
                     /locus_tag="ACZPB4_09400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011965945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SusC/RagA family TonB-linked outer membrane
                     protein"
                     /protein_id="HIR1098466.1"
                     /translation="MTGTVIDEAGIPVIGANILVKGTTNGTITDMDGKFTLINVPENA
                     ILVVSYIGYLDREIPVAGKSTLEIRLKEDTQKLDEVVVVGYGVQKKVNMTGSISNVKA
                     DDLSVIPSTNLSNSLAGRAPGATITGNSGLMGAKSEIRMRGGFGDPLFVIDGVIRDKE
                     AFDLLEPYEIDQMSFLKDAATASIYGSAAGNGVVLVTTKGGTKNQKPIFNYQGSYAFS
                     KPTQELFADRWDAIDDLDYQNAVARFQGTPLPNGEEEYAYFRDNKINYNVNDYIWQNP
                     WNTKHSLSVNGGTDKVKYYVMGSFLAEEGSYVSLENKKFSLRSNLSVDLTKYITMNVN
                     LDANQSNDKRFYWPFSDDDDQSVYDLYRCTFNAMKTTPFYSYLDGTPANTITDYPIYQ
                     DYGSWQGWNPVDQVVGNRYLKTRRRNLNGIVSFNINLDFITKGLSTKVMASYLGHDYN
                     RKRFMTFQKNYKFQQADPQGNRFLPAPLNLNEYNTFNFSQNYENLEYKTKQLWTEQFN
                     WFVNYANTFGKHDVAAMVVFEQASNGGEEVSAKGESPLTNLDQMFNYSSDALRRWGEA
                     KEKNGGRLSWIGRFNYTFDQKYIAEFSFRYDGNTLFPDGKRWGFFPSVSAAWRISQES
                     FMEPTSDWLSNLKIRASYGTTGNDMDLSKDPIDKVDAFSYLQKYQLGEKYIFGNNLAN
                     TIVAGATPNYALTWATSTTYNGGLDFGFFNNRLSGTFDAFYRKEVDILGPRTVTLPST
                     YGQALAPENYAERSWRGGELALTWMDKAANGEITYSAYLNLGFARDRWDVLDEDATYR
                     EGGNLHALSKQGKAEGILTGLIADHLLTDPAEVEALKAKGFKQFGRDPYLGGILYKDT
                     RGDGYSEGPDGRIDSNDEYNLLSENGTPRINYGFGGSIKWKGITLDVHFQGVGKYDRF
                     VGGVDGGFYQHGGTIRPYFPIWTSDKVYDPELNPDGVYPRITGTSWYESGAGNTSYWM
                     RNGAYLRLKNLNIGYDLPMAILRPLGITHAQVFANATNLFCISAVTEFLDPEQEYYDS
                     YPLMRTFSFGLNFSF"
     gene            23333..25132
                     /locus_tag="ACZPB4_09405"
     CDS             23333..25132
                     /locus_tag="ACZPB4_09405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0019867 - outer membrane [Evidence IEA];
                     GO_function: GO:2001070 - starch binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RagB/SusD family nutrient uptake outer membrane
                     protein"
                     /protein_id="HIR1098467.1"
                     /translation="MKMIQFKYAIISAAFLLGGMTTGCDTLDIDNLETYDESMVWGDL
                     NLAQAYVNNLYEECFEGWSVSADQNSDQVTGIPWYLGTITETGDSYKKWDYTKIRHIN
                     EAIFKLESSVIEDKKAVDFMLGQAYFMRAYMYYWMVLHHGGVPYLKVPQDKDKDDLYV
                     KRNSTPECFQFMIEDLDHAISLLPAKIAGSSSDYGRIDQCFAKSWKAKTLLLKASPQF
                     NPKRMYDNAYWKEAYVAAKEAYDFCVQNGIALTENPADIWLQERGPEVIFPVIYSNPN
                     RVATWEYGTRPASVSRDKPYHNPTWEFVKDFPMLDGKRYDDPTGKYYVGDEQALLKAF
                     WKNRDPRFNRACLYNGREWPVAGRSADNRMYNALGVSNADDQYGVNPNAGVNAANNDI
                     FSGMYNYKVSDLSLTQDKVMTFDIDYILMRFAEVMFIYAEAANENGHSDVAIDLLKQI
                     RKRAGIEAGADGLYGLKVGSREEIRQAILDERHIELCYEGHRFWDLRRTRNMMMLAGW
                     TKHGIEAIAVNPDGSDMDLNVARDRIAKNELTTGDFRYVIHQVPYTEAAERQFVIEES
                     FYFFPIKKTYLDENPNLEQNNNWGGTFNPTMEQ"
     gene            25165..26061
                     /locus_tag="ACZPB4_09410"
     CDS             25165..26061
                     /locus_tag="ACZPB4_09410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HIR1098468.1"
                     /translation="MNIRKYIWAYVVAMALICPGVKAQEQITIGVIQYDVRDIDKSFK
                     ALHEQGFGSCELNYSEKRFTKELAEQVKAASEKHRIRVTTLVGVPGSKSTWNFRQGPA
                     TIGLVPIDERFEKLDLYRKMIDFCVQAGIPAMHSHFGFIPEDPSSAQYKDFIEVMRGL
                     ATYAKERNVLIYFETGQETPITLIRAIRDIGTGNLFINCDLANLLMYGKSNSLDAVKL
                     FGNLIKEFHAKDGKYPDPNNPYELGHEVPIPTGDVDFPAVIAELKKQGFKGAITIECE
                     LNGTRHDYVIQTRKYLQELLDR"
     gene            26245..26439
                     /locus_tag="ACZPB4_09415"
     CDS             26245..26439
                     /locus_tag="ACZPB4_09415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HIR1098469.1"
                     /translation="MEEKKRLTRSNNKMIGGVCAGLAEYLDIDPTIVRIVWVLMVLFA
                     GFGILLYIILWLIMPKQQIG"
     gene            26443..>27527
                     /locus_tag="ACZPB4_09420"
     CDS             26443..>27527
                     /locus_tag="ACZPB4_09420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HIR1098470.1"
                     /translation="MNFEISSSFSPTGDQPEAIAALSEGIKSGVPFQTLLGVTGSGKT
                     FTIANVIKEVQRPTLILSHNKTLAAQLYSEFKAFFPNNAVEYFVSYYDYYQPEAYLPS
                     TDTYIEKDLAINEEIDKLRLRATASLLSGRKDVIVVSSVSCLYGMADPTAFAEKVTHL
                     ERGMRIDRDKLLRRFVDALYVNNKLEFKSGCFRVNGDTVDIFPAIETFDGMAYRIEFW
                     DDEIDRISSFNPLTGEEYDEQDELNIYPTNLFVTTQERINMAIGQIDVDLGTQVNFLK
                     EIGKPFEAKRLYERVTFDLEMIRELGHCSGIENYSRYFDGRAAGDRPFCLLDYFPKDF
                     LLVVDESHVTIPQIRAMYGGDYARKKN"
BASE COUNT         6683 a         6084 c         7231 g         7529 t
ORIGIN      
        1 aaacaggtat cgttgatgga ggagataccc ttgatgatgg ccttgccttc ctctttcacc
       61 cgctctttcg agatataggt tccgggagcg gtcgggttga aggtattcaa gatacggatc
      121 gggatattct tatgataaac cggatagatc gtcggcggat agattacttt cgccccgaag
      181 ttacacaact ccatcgcctc cgtgaaagta agccggtcga ttacgtaggc ggagctgatc
      241 acacggggat cagcggtcat gaaaccatcc acgtccgtcc atatctccaa ggtgttagcg
      301 tctaaggcgg tcgccaagat ggaggcggta taatccgatc cccctcgtcc gaggttcgta
      361 acctctccgg tttccgtgct ggaagagatg aatccgggca ccaaggaaac cttaggcagc
      421 ggcgagaagg tctcttttat gagcttgttg gtcaagtcga aatccacgat atgcttgttg
      481 aattgcttga ctgtcttgat atatttgcgt gagtcgaaca acttagcgtc cttgatcacg
      541 ttcgagacga tcaaggaaga taggcgctcg ccataactta cgatcgtatc ggatgtcttg
      601 gcggataaat cgttaatcaa ataaacacct ttgaaaatat tgctcaattc atccagtaaa
      661 gccatcactt tcttctggac atccatgcgt acctccttgt cctctatcac tccctcgatc
      721 acgtccagat ggcgggcgat gatctccgat aattctttct cgtaggcaag gtcgccttta
      781 gaagccatgg tagaagtggc cagtaattta tcggtgatgc cccctaaggc ggagacaacc
      841 acgattacgg gctcttcgat agcctctact attttcttta cacttaagat actattcacg
      901 gaacctacgg atgttccgcc gaattttaat actttcatcg atatgtattt ttaatggttc
      961 atcgaggatt gacaatcaag aaaaggcttt ttcatgatta gcaaccgaca ataaccgatt
     1021 gattaaactt atttatgtaa aaggagaaat aaaaaaggat gcaatacgag attgcgacat
     1081 agcgtgacgt ggtctacgcg aatgcttatt aatagattct aaccccccaa ggggtcatca
     1141 atgcccatgt ataatatgag gactctacac tcatcattga ttttgtatgc tacttattct
     1201 tttatattat gggggcaata ttacgcatta tttttcatat tgcaagcgtt tttgctaaaa
     1261 gattgactat tttgttgttc aaggtccgcc cggctcttgc tttgggtcac taaatagaca
     1321 ccggagaaaa caagtgcggc cgatactagt ttcgttacgc taaaactatc ctgaccgatg
     1381 aatacggcga taaaggaagc tacgatcggt tggatataat tgtacatgct gacggtagtc
     1441 gggcggattc gctttaaggc cagcggtatt aataaatagg gtatgaacgt ggccccgaat
     1501 aatacgaaga aaatggctcc cagctcttgg ccgtcgaaga cctctttatg gaaagccggg
     1561 gtattccaga tggactcgat agcgaaaggc agggtaatca gcgtggagaa caggaacatc
     1621 catttcatca tcgtgacgga tgagtacttg agtgttagtg gcttggatac taccaaatag
     1681 atcgagtaca tgaatccgct aaccgtaatc aagaggtttc cccctagact gctcgcttga
     1741 ttggaacctt gcgtggattg tagtattaag gagatcgccc cgcatatacc aagcagtacc
     1801 ccgaacgttt tcatccgtgt gataggttcc tttaggatca gggccgccaa gatcatgaca
     1861 aagatgggga cggcggtcgc tatgatggaa gcgtctaccg gcgacgtggt attcaatccc
     1921 cagataaaca gcccttggtt caagcctact ccgcaaaggg cgcaaaggca tagaagtccc
     1981 aagtccttca acggcacttt ctcataggga acgaataggg aggtgatcca gaacatcacg
     2041 caagcgaagc tcatccgcat actggttaac gcctcgggtt gcacatgctc ggggagtaga
     2101 tatttggata cgggcatatt aatggcgaac aggatgttgg ccgctaaaat aaggagatgc
     2161 ccttttagct tttcttgatt catcatgagt acgatcctag attggtataa tataatgtat
     2221 ataggcttat gttttggtga gcaaaggtct tacttttttt tgtaaataag aaatgatccg
     2281 ttagtaaagt gttttacata cggatcattg tctgtttagt caaggatgca tcccgttttt
     2341 attacgatga aacggccgct cctcccatga tatccagcaa ttcgttggtg atggcttgct
     2401 ggcgggtttt attatattgc aaagttaatt gttggattaa atcgttcgca ttgtcgttgg
     2461 cggtctgcat agccatcata cgggcggcgt gctcggcggt cgaggtgtcg agtaggatcg
     2521 tatagatggt taggttcagc aatttcggga aaagccggtt acgcaactct tccgccgagg
     2581 gctcaaggat gtagtcggtg gccgtttccg ccgcttccgt atccgagagg gaaaggggaa
     2641 gatacgtctt gtgggttacg acttgtgtcg ccatgttctt gaaatggtga tacagtaatt
     2701 ccacccggtc cgctttaccc gtgacgaaca gctccatgag acggttcgcc aaggatacgg
     2761 cgctttcata agacggcttt tcgccgatcg tgacgaaatc agtgtcgaag ctataccccg
     2821 ctttatgaag ctcatccgct attttcttgc cgatagggta gaggcctacc tctatttgct
     2881 ggttcttata agtctggatc gtggcggata actctttcca tatattggca ttgaatgtcc
     2941 cgcataaacc cgtgctcgag gcgaatacgg cgatagccac cttgctcacc ttacgctgtt
     3001 cggtgtaagg tgagtctagg tcgcattccg ccgaaagaag accgtttaag atagcggata
     3061 gtttattagc atatgtaagt gtgtgctcgg tttgcgtctg ggcatgatga aacttggccg
     3121 acgataccat tttcatggcg gcggtgatct tctgcgtact ccgtatagag gcgatccgga
     3181 cttttatttc tttcaatgaa cccatagctc cttcgctgtt ttttccaata tgcctcgtat
     3241 ctcatcattg ataacgccgg tctttaagac atccagtacg tcccgttgat gagaagtccg
     3301 taattcttgc aagaaccttg cctcgaactc atgcaccttg tccaatggaa cctctttcag
     3361 cagaccttgc gttccgcaat aaaggatcga gatttgctct tccaccggca tcgggctata
     3421 ttgaggctgt atcagtaact gggtattctt ctgcccctta tcgatcgtga aagcggtgac
     3481 ggcatccatc tcgcccccga acttggaaaa tgattccaat tcacggaact gagcctgatc
     3541 gattttcaag gtacccgcta cctttttcat cgcctttaat tgtgcgttac cgcctacacg
     3601 ggaaacggag attccgacat tgatagccgg gcggttccct tggttgaata aatcggtctc
     3661 aaggaatatc tgtccgtcgg tgatagagat cacgttggtc gggatataag ccgatacgtc
     3721 tcccgcctga gtctcgatga tcggtaaagc ggtcaaggag ccaccgcctt tcaccttgtc
     3781 tctcatgctt tcggggagat cgttcatctc acgggctacc tccggctgat tgatgatctt
     3841 ggcggcacgt tccaataggc gggagtgcag gtaaaagata tcacccgggt acgcctcacg
     3901 cccggaaggg cggcgaagga tcaaggaaac ctcacggtag gcgaccgctt gcttggacag
     3961 atcgtcgtag accaccaagg cgtgtcgtcc gctatcccgg aagtactctc cgatggccgc
     4021 tccggcgaac ggggcgaaat attgcatggc tgccgggtcg gaggcggtcg cgcttacgac
     4081 aatcgtatag tccatggcgc ctttctcttg caaggtgttc accaaggccg ctaccgtgga
     4141 acccttttgc ccgatcgcca cgtaaataca gtaaaccggg ttccctgcct cgtagttgct
     4201 acgttggttg atgatggtat cgatagcgat cgaggtcttt cccgtctgcc tgtcgccgat
     4261 gatcaactca cgttgtcccc ttccgatagg gatcatagcg tctacggcct tgataccggt
     4321 ttgcaaaggc tcgtttaccg gctgacggaa gatcacgccc ggagccttgc gctcaagcgg
     4381 catctcgcaa gtctcgccaa ggatctcgcc tttcccgtcg atcgggtttc ccaacgggtc
     4441 gatcacacgc ccgatcatcc cctcgctgac atcgatagag gcgatgcggc ccgtgcgttt
     4501 tacggtgtcg ccctccttga ttcggtcggt cggacctaaa aggacggcgc ctacattatc
     4561 ttcctccaag ttcatcacga tcgcttccat cccgttatcg aattgaagca actcgttcgc
     4621 ctccgcatta tccagcccgt agatgcgggc cacgccgtca ctcacctgca atacggtccc
     4681 gacctcctcc agcttgatgc tggtatggat tccttccaat tgctggcgca ggatggagga
     4741 gacttcactc acttttatct gttctgtcat acttcttctt ttttatctgt tttcgagtag
     4801 cccggtacgg atatcccgta gttgcgtcgc atagctggcg tctatccggt aattgccgat
     4861 gcgtaggcgg aagcccccga ttagttccgg ttccacgtgg ccggagaact cgattgtgca
     4921 tcccgtctct ttccgcagct tgtcttgcag gtgagacttg accgcatcgt ctaccgctac
     4981 ggccgtgtcg aatcgtaccc gggtaatctt cttctctttc cggtacaaat ggatataaat
     5041 gtatgcaatg aagggcagta acgtctcccg tttatgggct aataccagat tgataaaacg
     5101 tgaatatagc tcgcatacct cgatacctcc cgccgccgta agcaatttca ctttctccgg
     5161 tacggaaacg atcgggttgc tcaaggcacc cctaagctct ggctccatcg agaagctgtc
     5221 cgccaacatc ttcatatcat catatacccg gctttcctgt tccttgtctt tcgctaggga
     5281 gaaaagcgct ttggcatacc gggaagaaat agttcctata tccatacctt acgatttact
     5341 aaacgatacc tcatccagca gccggtcgat catctgttgt tgttccttat cccggccgat
     5401 tttctctttc attactttct ctgcgatagc gatagacaga tccgctatct ccgagcggac
     5461 ttcgcgaata gctttctctt tttcttcgcg gatacgccgg gtagcctcct ctatctgcag
     5521 atgtgcctcg gagacggcct ttttccgtgc ctcctcgatg atccgctcct tttcggcaaa
     5581 ggcttccttc aggacggcgt tttgcttttc cttggcctcg gctagcatct tctcgccctc
     5641 ggcttggata tgggcaagtc gctcattcgc ctgacgtgcc gtctctaagg aattgtcaat
     5701 gtaagctttc cgttgttcga ttgccttgac gatcacggga aaaccgtatt tggaaaggat
     5761 cacgaagaca atcccgaatg aaacgatcat ccagaataga agccctgaat ccggtgttaa
     5821 taaagacata gtttgttact tttttattgg aacaacgcta agaaacatac gacaatagcg
     5881 aacaatgcca caccttctac caacgctccc ataatcaaca tcgaggtacg gatctctcct
     5941 gcggccgacg gctggcgtcc aatagcttca acggcacctt taccgatcaa tccgattccg
     6001 atacctgcac ctatggcggc gaatcccgct cctatagtgg ctcccatctt cgctacgccc
     6061 atcccggctg ccgcttgtaa taaaatagtc gataacatag tgtttaattt taaattagta
     6121 accttaataa tataattcta ataccttaat ttctttggat ttattccctt actttggcca
     6181 atccgatata gttggccgac agcagggtga aaatataagc ttgcaagcaa gccactaaca
     6241 attccagaca gttcatgaac gcacagaaca agacggatac gatcgtcata cctaaattca
     6301 cggctactcc catcgttacc gttatgaata tcaaacaggt tagcgccaag ataatcgtat
     6361 ggcccgccat gatgttggcg aacagacgga tcatcaacgc gaacggcttg gtgaataccc
     6421 cgaagaactc cacgaacggc atgatcggca agggcagttt caagtagatc ggcgctttgg
     6481 gccaaaaaat ctctttccaa tacactttcg tggcgaacag gttgaccgct ataaacgtac
     6541 aaagtgccaa tacgcctgtt accgctatat ttcccgtaat attagcgcct cccgggaaaa
     6601 ccggtatgat cccgatcagg ttattgatca agataaagaa aaataccgtc agcaaatagg
     6661 acgagaacgg cttatattct tttccgatcg cctctttgat caccccgtct tgtatgtagg
     6721 agatggccat ttccatcaat ccgataaatc cgcccggcgc ctcgttcggg tgctttttat
     6781 accaatgggc ggttcggaga acgatgaaaa gcaagagacc gcaactgagg aacagtccgc
     6841 aaacattctt ggtcaatgag aaatccatcg ggcgaacctc ttctccggca ctgttcttct
     6901 caacaacctt tcccgcatgc tcaccttccc cggcgatata ataattgtga tgcgtccggc
     6961 cttgatgtag atgggatgac aggaataaat cccatcctct ttcctcgctt tttaccaaga
     7021 taggcagggg aatcgcaatc tcttgtccgt tccattccgt gatatgccat gtataggcgt
     7081 cttgaatgtg ggagaagacg atatcctgca cgtctatctc gccggacgcc gcttttgccg
     7141 gagtgagaaa gctgagccac atccagaaag cgatccatat gtatttgtta tctttgattg
     7201 tactcatcat ccttttccct tttctctctt ttcattcttt tcttttcaaa cagatataaa
     7261 atgtaagtct ccagtccgag gtaaatgaaa tagaataaca tcaacgtgaa accaaatgtc
     7321 tttaattgtt gcccgacaaa cgccgcgtac atccataaga agacgaaagc gagcgtgaac
     7381 ttacacaacc ggactagcat gtacatggtt acggtcacat ctccgttttt cctttttacc
     7441 cggtctagga agaaagtcat cgccatggcc atgacccagt aaaagaaggg aatggacgga
     7501 taccacgaga aatagtgttc cggccagatg gtatataata aaccacccaa tgaaacgcct
     7561 attgccacgt tgataaacgt gatcaaaccc attaacctca tttttaatct gccattcatt
     7621 gtcgtatgtt tttattcgac gcaaacggat aggatgtcgt cttttacctc tacgaatccg
     7681 ctttgtatcg tttgttcttg tcttttgccg tttgcctcga accggatcgt acccgccttc
     7741 aacgctgcta tcaatggggc gtgatgaggc aagatatcga atgaaccggc aactcccggg
     7801 aatgagacag attcggtctc gccttcgaaa agaatgccgt ccggtgatac aatttccagt
     7861 ttcatatcga ttaatttgct tgttctttca gctgcttggc cttctccaag acatcctcga
     7921 tggttcctac gtttaagaat gcctgttcgg gtatgtcatc cgtttccccg tccatgatca
     7981 tcttgaatcc ccggatcgta tcctctatag agaccatgac accgggtacg ccagtgaatt
     8041 gttccgccac ggagaagggc tgggacagaa aacgttgtac acggcgggcc cggttgaccg
     8101 ttagcctgtc ctcgtcggaa agttcttcca taccgaggat ggatatgata tcttgaagtt
     8161 ccttgttccg ttgcaggatt tgttttaccc gttgcgctgt gtcgtaatgc tccttgccta
     8221 cgatcagcgg atcaaggatg cgggatgtag attccagcgg gtctacggcc ggatagatac
     8281 cgagttccgt gatcttgcgg ctgaggacgg ttgttgcgtc caaatgcgta aaggtagtcg
     8341 ccggagccgg gtccgtcaag tcatcggcag gaacatacac cgcctgtacg gaggtgatgg
     8401 agcccttctt ggttgaagtg atacgctctt gcatagctcc catttccgtg gccaatgtcg
     8461 gttggtaacc tacggcggaa ggcatacgcc ccagcaaggc ggaaacctcg gaaccggctt
     8521 gggtgaaacg gaagatatta tcgatgaaga ataatatatc ttttctttct ccctcagagg
     8581 ctttgtcacg aaaggattcg gcgatcgtca aaccggataa ggccacggac gagcgggcgc
     8641 ccggcggttc gttcatctgc ccgaatacca aggtagcttg cgacttagcc aattcatcgt
     8701 aatcgatctt cgacaagtcc cagttacctg cctccatact cttcttaaac tcctcgccgt
     8761 atcggatgac accggattgg atcatttcac gcaataggtc atttccttca cgtgtacgtt
     8821 cacccacacc ggcgaagacg gagaatccgt tgtttttctt tgcgatgttg ttgatcaatt
     8881 ccatgatcaa taccgttttg cccactccgg ctcctccgaa aagtccgatc ttacctcctt
     8941 tggcgtaagg ttccaataaa tcgattactt taatacccgt gtacaggacc tcttgggtcg
     9001 ttgtcagatc ctcgaattta ggaggctcac gatggatggg aagagccccg tctttagtaa
     9061 gctgggccat gccgtcgata gggtcgcctg tgacattcat taaacgtcct ttgacttggt
     9121 cgccggtcgg catggtgatg ggcattccgt atgacatggc ctccatgcct cgtctcaatc
     9181 cgtcggtcgt atccatcgct acggtacgga cggtgttttc cccgatgtgt tgctgaactt
     9241 cgacgatcaa gatctttccg ttcgggcggg aaatctccat ggcgtcgtgg atacggggga
     9301 gggttactgt ttcttctgtc ccataatcaa agtggatatc cactaccggg ccgataacct
     9361 gtgagatata gccttttatt tctcccataa agcctatttg ttatttatct taacctatta
     9421 aaatgtcgtt gcaatattac gttttatggc gtttcgatcc ttgaaaatag aactttttgt
     9481 gtctttttga gattagttaa actttaaact atttagctat agttccgaaa tagaccaatt
     9541 tgtttcttat ttggacgaat cagaaagcta tagtcaaatt tctaaggcat agatagataa
     9601 ggagatacga atttgctgcc tttttgatag taaaggtgat agttctgttt tattttgtta
     9661 atccataata ggggtgtttt taatggtatc ggatagttat ttgtggttct gttgagcaag
     9721 tggtgatatt tatgtaattt tgtacgtcaa caatactaaa taaacatgaa acgaattatt
     9781 gagatatgtg cgaactccgc tcaaagctgt gtggaggcgg aggcgggagg cgctacccgt
     9841 gtagagcttt gcgccgggat acccgaaggg ggaactacac ctagttatgg agagatcaag
     9901 acggcgaagg ctctgacttc caagatcgat atcaatgtga ttatccgtcc gagaggcggt
     9961 gatttcttgt atacggaagc cgaggtgcaa tccatgctat tggatataga actgtgcaag
    10021 gagctaaagg tgcatggcgt cgttttcggc tgtcttacga aagacgggga tatcgatgta
    10081 cccttgatgc ggcgcttgat cgaggcggca aaacctctgt ccgtaacttg tcatcgtgct
    10141 ttcgatgttt gccgggaccc attcactgcg ttggagcagc taatcgagtt gggatgcgac
    10201 cgtatcttga cctccggcca gcaatcggat gccgtgaaag gaatcccctt gatcgccgag
    10261 ctggtgaaac gtgcggacgg acggatcatc atcatgccgg gatgtggcgt acgtgagaat
    10321 aatatcggga aaatagaggc ggagacagga gcgaaagagt ttcatacgtc cgcccgaagt
    10381 atcgtatata gtaaaatgga ataccgcaat gagaatgtcc cgatgggaag cagtatcgtg
    10441 tcctccgaat tcgagacggt gcaaacggat cgggagaagg taaaagcata tatttaagtg
    10501 ctggtatagg cgtgagcctg tgtcggtatt ggtgtagccc tacgcctata ccggcatcgc
    10561 ctcatgccta taccggcgtg gggcgatacc aatactcgta tgcgggtgaa atgttttttc
    10621 ttcccaaaaa gattgtttat ctttgcgcct ccattagata aaagatgcta aatgtaacag
    10681 tgaataatcg ttttgggttt caccagcgta tcatgcttat gatcatgttg gtgctgttac
    10741 agttttattc cattggaagc gatttctttc cggagaatat taccactacc tcgatggaaa
    10801 tagtcgataa agaggcaccc gatgtgttgt tggattttga cgataacgcc tccttgcgaa
    10861 cggtacgtca ggagcaagtg caaatccgag ccttggagat cgatttgata tgggacttgt
    10921 ttacgattct ggatttacat gaattaattc attccttgga actacggcaa tgcgccaagc
    10981 ttcctttatt ttataaccta cacaaagcac agaatttcgt ttggttctgt tcctatctga
    11041 tttagtagaa cttacctgtt tcttattgtc gcgcatgggg tgattcgcct atgtgctttt
    11101 cgtcgtattc aaataattat aaatctataa gttttatgag gataaaattg ttttctaact
    11161 atttaccctt actatgctta acggcttgtg tatgggtatc ttgtagccaa aaccgggaga
    11221 aaaagtccgg gaagaaagat catacgccgg tgatgcggtt aaccacgacc acgatcgagg
    11281 tgccgcagtc ctatgtagcg gatgtacaag ccgtacagtt cgtagaggtg aaaccgaaag
    11341 tggaagggtt cgtggaggcc gtccttgtag atgagggcga gcacgtgaag aaagggcagg
    11401 tgcttttcaa gctttcctcg gcggaattgt acgaggaggt gaaagaggcg caagccaatc
    11461 acaaacaggc ccaagccgag ttgaagatgg cggaggtaga ggtagaccgc atcaagcgtt
    11521 tggtggagaa agatatcatc tcgccgattc gtctggagca ggcgatggcc gaggcggacg
    11581 tggcacgctt gcaggtgcaa caggccaaat cccgtttgca acgtgcggag actaatttct
    11641 cgtacacgac gatcacggct cctttcgagg gatacgtgga ccgcatcccc tttaaggtgg
    11701 gaagtttggt tacgccgagc agcttattga cctccttgac ggacgtatcg gatatgttcg
    11761 cctatttcaa gatcaacgag aaggagtatc tggaatataa acggacgcag ttgagcggta
    11821 tcgaccagcc ggagtataat aatctagagc tgatcctttc cgaccaatcc acctatcggt
    11881 ataaagggaa ggtagagacc gtggagggcg actttgagcg gggtaccgga tcgatcgctt
    11941 tccgtgcccg tttcgcgaac ccggaacgtt tgctgcgaca tggcgtatcc ggtaagatcc
    12001 ggatgctgac caagatggag aacgtggtct tggttcccca gcaatccact ttcgagatac
    12061 aggattttac ctatgtatat acggtagcgg aagatggaaa ggtgagcgtg cgtagcttcg
    12121 agccgttggc ccgccacggt tcttattacg tgacacagga tttgccggac cagaccgtca
    12181 tcgtctacga gggtgtccag atgatcacgg acggcatgac tatcaatccc gatatggtag
    12241 atggagccac gatccgtcgc caattggaat cgtctaatga aatcgagaat aataagtaag
    12301 ccctatgttt gaaatattta tcagacgccc tatcttatcg ggcgtgatct cggtggtaat
    12361 tgtcttcttg ggattgctgg cgatcaactc cttgccgatc acccaattcc cggatatcgt
    12421 gcccccatcc gttaccgtta ccgcccgtta taccggagcg aacgccgacg tgatggcgaa
    12481 aacggtggcg accccgctgg agcgtgctat caacggcgtg cccggaatga cctatatgac
    12541 ctctgtttgt acgaacgacg gtatgtcctt gactacgatc tatttcaagg tcggtaccga
    12601 cccggacgta gcttccgtga atgtgcagaa ccgtgtgacc accgtgctgg atgagcttcc
    12661 ggaagaggtg atccgtgccg gcgtgattac ggagaaggag gtgaacagta tgttgatgta
    12721 cctgaacatc atgagttcgg atagtaccca tacggagaaa ttcgtatata actttgccga
    12781 tatcaatatc ttgcgtgagt tgaagcgcat cgacggcgtg ggattcgtgg agatcatggg
    12841 tagccgcgac tatgcgatgc gtgtatggct gaacccgaac cggttggcgg cttataatat
    12901 gtcgccgcaa gaggttacgg aggcgatccg ctcgcagaat atcgaggcgg cgccgggtaa
    12961 gacgggtatc agctccgaca agatcccgca gcaattgcaa tacgtcttgc agtatagcgg
    13021 taagttcagc acgccggagg aatatggcga gatcgtcttg aaagccctgc cggacggttc
    13081 cgtgcttcgc ctgaaagacg tggctacgat cgagtttgat tccgaggatt ataatatgat
    13141 ctccatgacg gacggaaagc cctcggcctc tatcatgatc aagcagcgtc cgggctcgaa
    13201 cgcccgtgag gtgatccagc agatcaaggc gaagatggag gaattgaagg aaacgacgtt
    13261 tgccccgggt atggaatata atatctcgta cgacgtatcc cgtttcttgg acgcttccat
    13321 atcggtcgtg ctcaagacct tgctggaggc gtttatcttg gtatttatcg tggtgtatct
    13381 tttcttgcag gatttccggt ctacgttgat acccgctatc gccgttccgg tatcgttgat
    13441 cggtacgttc ttctttatgc agatgctggg tttctcgatc aatatgctga ctttgttcgc
    13501 cttggtgctc gctatcggta tcgtggtgga taacgcgatc gtggtggtag aggcggtcca
    13561 cgtgaagatg cacaacgaga agctgccccc gttgaaggcg acgaaaaagg cgatcggtga
    13621 gatcggaggg gcgattatcg ctattacgct ggtgatgtcc gccgtgttta tcccggttgg
    13681 tttcatggat ggtacggtgg gtatcttcta tcgccagttc tcattgacgc ttgctgtggc
    13741 gatcgtgatc tccggcgtga acgccttgac gttgtctccg gctctttgcg ccttgttact
    13801 gaagccggta tctcattcga aaaaggcgaa gaagggcctt ctgactcgtt tcttcgaggg
    13861 ctttaaccgc cgttatgatt tcttggagcg tcgttatcgc ttgaatttaa gatggttctt
    13921 gaaccgtcgg atgctgacgt acgcaacctt gatccttttc tgtctggcca catggggcat
    13981 gacgttcgtg ttgccttccg gctttatccc gaacgaggac caaggtatga tctatgtgaa
    14041 cgtagatgcg cctcccggag ctaccttgga gcgttcggaa gcggccttga acaaggtgca
    14101 agcggctttg ttgccgttgg aagaggtgga gacgatctct accttggccg gctatagctt
    14161 gatgaccgag acggagggtg ccagcttcgg tatgggtatg attaacctga ccccttggga
    14221 tcaacgggag cagacggcgg cggagttgat gagcgtgtat gccgatcgtg tcgcccatat
    14281 caaggatgcg gacatccagt tcttcctgcc gcctacggtt ccgggattcg gtaacgcgag
    14341 cggcttcgag cttcgtctgc aagataagac cgccggtacg ttcgccgagc tggatgaggt
    14401 cgccaagaac ttcgtggcga agctgaacgc tgatcctcgc ctgaccggtg tcacttctgg
    14461 cttcaacccg aatttcccgc aatatctgct ccgggtggat ttggcgaagg cggctaagct
    14521 aggcatcaac gtgaacgagt ccatggaaac cttgcaatcc tatgtaggta gcttctactc
    14581 ctccaacttc gtccgtttcg gccagatgta caaggtcatg ttgcaagcgg cgccggagta
    14641 tcgtatgaat ccggaggatt tgttcagcct gtatgctaag aataaggagg ggaatatggt
    14701 gccttactcc aacttcatga cgatggagcg tgtgtatggc ccgagccaga ttacccgtta
    14761 caacctgttt acctcggcca tgattaccgg cgaggccgcc ccgggtgtca gctcgggtga
    14821 ggcgttggcg gctgtcgagg agatcgcttc cgaggtattg ccccgtggtt acgataccga
    14881 atggtccggt gtggcgaagg aggagaaaga gtccggcggg caaacgttgg tgattttcgc
    14941 tatttgtttg gcattcgtct atctgttgct tgccgcccaa tacgagagct tattgcttcc
    15001 gcttccggtc atcctgtcgc ttccggcggg tgtgttcggc tcgttcttct tgctgtacgt
    15061 ggtagggctg gagaataaca tctacgcgca ggtggcgttg gtgatgttga tcggtttgct
    15121 gggaaagaac gcgatcttga ttatcgaggt ggcgaaccag tgccgtaagg aaggtatcag
    15181 cgtgatgggg gccgctattc aaggggctac cagtcgtttg cgcccgatct tgatgacctc
    15241 cttcgctttt atcagtggct tgattccgtt gacgatcgcc tcgggagccg gtgccttggg
    15301 gaaccgttcg atcggtacgg cggcggccgg aggtatgttg atcggtacgt ttgtcggtat
    15361 cttcttgatc ccggggcttt acgtgatctt cgagtcgctg gctacttatt ttaaaaagag
    15421 aaaagagaaa gagcaaatta aagaagacga gtatgtgtat tgataagatg agatatataa
    15481 tgataggctg cgccttggct ctgattgctt tggccggttg taagactccc gagctattga
    15541 tggacgagcg gatctcgctt ccggaatccg gcgagatggg aatgaacgac actacgttcg
    15601 tgaaaccgct ctcgtgggat gtctttttcc aagatacctt attgcgaggc tatgtggatg
    15661 tggctttacg caataaccat tccttccagc agagcatgga gcgcatcgcc atgagccgtg
    15721 cggccttaca gcgggcgaag gggcttttgc tgccggacgt gaatttgaac atcggagcct
    15781 ccgtgaaccg tttcggtgaa tatacgatgg atggtgtggg gaatagcgag acaaacgtgc
    15841 cttctttgcc aaaggataag catataccgg acccttaccg ggatttcggc ttgagcttga
    15901 gctttcaatg ggaagcggat atctggggca aactgacccg gaagaagcag gccgccgccg
    15961 ctcgctggat ggcttccgtg gaggctaccc gttttgccca gtcgatgttg atctccgatt
    16021 tggcgattca atattatgag ttgatcggct tggaccggcg taaggaggtg ttgcggaatg
    16081 cgctggccag tgcccgtcgt tcccatgagc tgacccgcca gttgaagaag gaaggggcgg
    16141 agacgcagtt ggcggtcgat cagttttatg cccgtgtgtt gttgatcgag agtaaattgc
    16201 tggaaaacga tcagttgatc ggtgagaagg agcgggcgat cgcttgcctg ttgggtgttt
    16261 tccccttcga gattcgccgg atgggattcg atgagttgcg taagttgccg gttcccttgt
    16321 cggaagggat tccagcgaac ctcttgacat tgcgtccgga tgtacgttcc gccgagatgg
    16381 ggttggtcgc ctccaaggcg gatgtgatag cggcgaaggc ggctttctat ccctcgttgg
    16441 tgcttggcgc cagtggtggt ttcaatgcgt ttgatgtggg taagtggttt cattcgccgg
    16501 cctctttggt gtacgacttg gcggcgggta tcacggctcc tatcttccgc cgcaatgaga
    16561 tccgttcgat gtggaacgag gcgaaggctt cccagcgtat cgctttatcc caataccacg
    16621 agaccgcttt gaacgcttac accgaggtgc tcgatctcta ttgcgccagc cagacccaaa
    16681 cggagcgtat ccgcttgaaa gagaaagaat cccttgccca ccaacgttcc gtggtgaatg
    16741 ccggcgagat gttccaatta agctataccg gtttcttgga ggttctttcc gccgaggagc
    16801 gttatctgga tagcgagctg gagcatatcg atatcgtcac cgatttatgc cggaagaaga
    16861 tattgctgta ccgggcgttg ggaggcggtt gttgattttt atcgtgacgc tattgttatt
    16921 gtactgcaac ccgcattgca gtgttactgc acgccggttg cagtagcgct gcacgtgcgt
    16981 cgcagtacta ctgcaatacg ggttgcagtg aatacttgat atcgtatgcc tttggctacg
    17041 ttgcgataaa tcttgggaag atgtgctctt ttctgaaaag aagtgcttat ctttgaagct
    17101 tattgttatc ttatagtcta ggccattatg aaatatctga ctctactcgt gtttttagga
    17161 atctcgttgt tgtgcgaagc ccagcaagat tcgatcgtcc cttttgagaa agcttataag
    17221 cgtacctata atatccggaa agtatcggga gtgaaaccta cgatcgacgg taagttggat
    17281 gaggactttt ggacgaagca aggcgaatgg tcggatcgtt tcgtacagat tatcccttat
    17341 gagcgggcga tcactcaatc cccgacccgg gtaaaacttt tctatgatga taaatatatc
    17401 tatgtaggtg tatattgcaa ggacgccgtg ccggataaga tgaatcgttt tatcgggaac
    17461 cgggatgata atagtctggg cgatttgatc agcgtcgctt tcgacaccta ccatgattat
    17521 cgtgcggcac cggaattcaa tatcaatcta ggaggaaata agacggatct ggtcgtaacg
    17581 gataagttga acgtcaacct tagctggaac gccgtttggg aaggacgaac gaatatcaac
    17641 cgggcggatt ccagttggac cgccgagctg cgtatcccgt tcagccagtt gcgttataac
    17701 cagcgatcgg aggatggcgt ttggggcttg catgtacgcc gtatcatccg taggaataac
    17761 gaggtgcaaa attggagcat gatccccttg aagaataacg gacatgtctt ttcgttcgga
    17821 aacatgagcg gcatggactc tgttcccaag cctcgcggca tcgagttctt gccgtatgta
    17881 atgggtaaat acaggcagga accccggata gacggcagcc cttatcaaaa agggcatagc
    17941 tggggaggaa acgtgggctt ggacgctaag ttcgccctct cggattatac gttggatatg
    18001 acgatcaatc cggattacgg acaagtggag ttggacccct ccgtaatgaa ccttacggct
    18061 tacgagacgt tttacgatga gaaacgcccc ttcttcttgg aaggaaaaca tatcttggat
    18121 tttgcgaacg gtagcgatat gatgttttat acccgtagga tcggcgcctc tccctcttat
    18181 acgccacggg gtatagacaa cgtaggcagt tatgccgaga cgaaagagaa tgtgccgatt
    18241 atcggtgcgt tgaaactgac gggtacgaat aaacggggct tgacgatcgg agtgatcgag
    18301 agtgtaacgg cacgttcctc ctccaaggtt acccgtaacg gggtggagga tgtggaagtc
    18361 gtggagcctt tgacaaacta taccgtggcc cgtgtgcaaa agaactggaa ggggaatacc
    18421 ttgctgggcg gtatggtgac ttcggtaaac cgtgccttgg atcagcctta tctggaggat
    18481 ttcatggtgc gtaacgcttt cacggcgggt attgacttta cccagtattt caagaatcgc
    18541 ctttattata tagatgtaaa gggaatgttg agttccttgc atggtagcgc cggggcgatc
    18601 acggctttgc agaatagcgt ggcgcattat tatcaaaggg cttcctccgc cgattatctg
    18661 ggggtggatc ctacccgtcg ctccctgacc ggaacgggtg gttatgtgaa agtgggacgg
    18721 aaaggaaacg ccaaatggaa cttctcggag acctttactt ggtcatcacc cggtttcgac
    18781 ttgaatgata tgggatatat gaaggagaca gattatctga tgaatgagac ggagatcatg
    18841 tatcggcaga ccgatatctg gaagatattc cggtacaacg cctttaccct gtcccaaaag
    18901 aatatgtgga attacggcgg tactcctttt agcaacaacg cttctttgcg ttggcaaagt
    18961 atgacgatga accggtatga atgggatgtc aaggaaacct ttgcttggaa ttggctggat
    19021 agccgcttgc tgcgaggggg accggatgtt cgcttcggtt cttatttctt aacttccgct
    19081 aagttcaata ctgataaggc gaaacgaatg atgttcatgc tcaaatacga gggcgatcat
    19141 aatttcgagg gaaatcgctt caatacgatc tcgccgagct tgacattccg cttgggaaac
    19201 catgtctatt tgtccggtca actggattat gcgtggaata cggatgagat gcaatatgtg
    19261 gctacgacga gtccgcttag ctcgagtagc ttgacccctt attattatgt catgggccac
    19321 atggatcaga agacctatgg cctcacgctg aaattacaag tgaacgtgac ccccgatatt
    19381 tccattcaat tttatggtgc cccgttcacc tccatcgcta aatacgatga ttttaaatta
    19441 gcggcggata cgaagtcgca tacctttgag aaccgtttcc aacgtattga tccggatcat
    19501 ttaacttatg tggatggagt ctataccatc ggggagggag ctgggcagat gccttttagg
    19561 aaccctgatt ttaggtttaa cgagtttcgt tccaacttgg tagcccgctg ggaatacttg
    19621 cccggttcca cgctttattt cgtatgggaa caccggatgt ctaaccggga caactggtac
    19681 tcctccggct ggggaagtaa tctggatcgt atgtggggac tccccgctac aaatacgttc
    19741 atgatcaaaa tgaattattg gttcaatcta tagtctattt gtagttcgga ttgaattatt
    19801 gaatggatgt tggcggaacc tgatcgtgtt gtttgttttt tatgattttt atttatattt
    19861 gcggtgaaaa gaaaaatgct tctcaatgca aacaagattt tgaggcaagt taaccttgat
    19921 gtttaatgaa taaatcttaa attttagata tggtgagaga tggatagaac agtgtgtggg
    19981 taatctcatt cagatgagat gtttttgaaa agaattttta gtataattca agtgtaaaag
    20041 agacttaaat ctagttttat gaataataaa tattacttag caacggtgct tttagcgtta
    20101 ggagcgttct ctccgttgta tggtgtacaa aatacccccc cccccataat tattctgtaa
    20161 atcagaatga tataagattg acgggtaccg ttattgatga agccggtata ccagtgattg
    20221 gtgcaaacat tcttgtaaaa ggtacgacaa acggtacgat taccgatatg gatggtaagt
    20281 ttacgttaat caatgttcct gaaaacgcaa tcttggtggt ttcttatatc ggatatctag
    20341 accgtgagat tcctgtggca gggaaaagta cgttggaaat ccgtttgaaa gaggatacgc
    20401 agaagttgga tgaggtcgtt gtcgtaggtt atggagtgca gaaaaaagtg aacatgaccg
    20461 ggtctatatc gaacgtgaaa gcggatgatc tatctgtgat cccgagtaca aatctttcaa
    20521 actctttggc cggacgtgct ccgggagcta cgatcacggg caactctggt ttgatggggg
    20581 ctaaatccga gattcgtatg cgtggaggat tcggtgatcc tttgttcgtt attgatgggg
    20641 tgattcgcga taaagaggct ttcgacttat tggaacctta tgaaatagac caaatgagct
    20701 tcttgaaaga tgcggctacc gcctcaatct atggttccgc tgctggaaat ggtgtcgtgt
    20761 tggtaacgac taagggagga acgaaaaacc aaaaaccgat atttaattac caaggttctt
    20821 atgcgtttag taaaccgact caggaattgt ttgccgaccg ttgggatgcg attgatgatt
    20881 tggactacca gaatgcggta gctcgtttcc aaggtacgcc gcttcctaat ggcgaggagg
    20941 agtatgccta tttccgtgat aataagatca actataacgt gaacgattat atttggcaga
    21001 atccctggaa tacgaaacac tccttgagcg tgaacggtgg tacggataag gtaaagtatt
    21061 atgtgatggg atcgttcttg gccgaggagg gatcgtatgt gtcgttggag aataagaaat
    21121 tctccttacg ttcgaacctt tctgtcgatt tgaccaagta tataaccatg aatgtgaact
    21181 tggatgcgaa tcaatcgaac gataagcgtt tctactggcc tttctctgac gatgacgacc
    21241 aatcggtgta cgatttatat cgttgtacct tcaacgcaat gaagacaacg ccgttttact
    21301 cttacttaga cggaacgccc gctaacacca tcacggatta tccgatctat caagactatg
    21361 gctcttggca gggatggaat cccgtggatc aagtggttgg aaaccgttat ttgaagacac
    21421 gtcggcgtaa tttgaacggt atcgtttcgt tcaatatcaa ccttgatttc ataacgaaag
    21481 gtttgagcac gaaagtgatg gcctcttatc taggccacga ttacaaccgg aagcgcttta
    21541 tgaccttcca gaaaaactat aaattccagc aagcggatcc gcaaggcaat cgttttttgc
    21601 cggctccatt gaatttgaat gaatataata ccttcaactt ctcgcagaat tacgagaatc
    21661 tggagtataa gactaaacaa ttgtggaccg agcaattcaa ctggttcgtg aattatgcca
    21721 atacgttcgg taagcatgat gtggcagcca tggtggtatt cgagcaggca tctaatggtg
    21781 gcgaggaggt atcggccaaa ggtgagtctc cgcttacgaa tttagaccag atgttcaact
    21841 actcatccga tgctttgcga cgctggggcg aggcgaagga gaagaacgga gggcgccttt
    21901 cttggatcgg ccgtttcaat tatacatttg atcagaagta tatagcagaa ttttctttcc
    21961 gttacgatgg taataccctt ttcccagacg gtaagcgttg gggcttcttc ccctctgtat
    22021 ctgccgcatg gcgtatcagc caagagtctt tcatggagcc gacatctgat tggttgagta
    22081 atttgaagat ccgtgcctct tatggtacga cgggtaatga tatggatttg agcaaggacc
    22141 cgattgacaa ggtggatgcg ttctcttatt tgcaaaagta tcaattgggt gaaaaatata
    22201 tctttggtaa taacttggca aatacgattg tggctggagc gactccgaac tatgccttga
    22261 catgggcaac ctcaactact tataatggtg gtttggattt tggtttcttc aataatcgtt
    22321 tgtctggaac gttcgatgcc ttttatcgga aagaggtaga tatcctcgga ccgcgtacgg
    22381 tgacactccc aagcacgtac ggacaggctt tggctccgga aaactatgcc gagcgttctt
    22441 ggcgaggcgg tgagttggct ctgacttgga tggataaggc cgcgaatggc gagattactt
    22501 actctgccta cttgaatctg ggattcgctc gtgatcgttg ggatgtattg gatgaggatg
    22561 ccacttatcg agaagggggt aacctgcatg cgttgtcaaa acagggtaag gctgagggaa
    22621 tcttgacggg cctgatcgcc gatcacttgc tgacggatcc ggcagaggtg gaagccttga
    22681 aggcgaaagg tttcaagcaa ttcggacggg atccttatct gggtggtatc ttgtataagg
    22741 atacgagagg cgatggctac tcggagggac cggacggacg tattgatagc aatgatgagt
    22801 ataatttgtt gagtgagaat ggtacgccac gtatcaatta tggttttggc ggtagtatca
    22861 agtggaaggg aatcacgctg gatgtgcatt ttcaaggggt cggaaaatat gatcgcttcg
    22921 taggtggcgt agatggaggt ttctatcaac atggtggtac gattcgtcct tatttcccga
    22981 tttggacgag tgataaggtg tatgatccgg aacttaatcc ggatggggtt tatccacgta
    23041 tcacgggcac gagttggtat gagtctggag cgggtaatac gagttactgg atgcgcaatg
    23101 gcgcttattt gcgtttgaag aatctaaata ttggttacga tttgcctatg gctattcttc
    23161 gtccgttagg aatcacgcat gctcaggtat ttgcgaatgc tactaacttg ttctgtattt
    23221 cagctgtgac cgagttcttg gatccggaac aagaatatta tgattcttat cctttgatga
    23281 gaacgttctc ttttggtctt aatttctcat tctaaatata atataggaag atatgaaaat
    23341 gattcaattt aaatacgcga taattagtgc ggcctttctg ttaggtggaa tgacaacagg
    23401 ctgtgacacg ttggatatcg acaacctaga gacctacgat gagtctatgg tttggggaga
    23461 ccttaatctg gctcaggcgt acgtgaacaa tctgtatgag gagtgttttg agggctggag
    23521 tgtttctgcc gaccaaaatt cggatcaagt gacgggcatt ccttggtatt tgggtacgat
    23581 cacggagact ggggatagtt ataaaaaatg ggactatacc aagatccgcc acatcaatga
    23641 ggcgatcttt aaactggagt ctagcgtgat agaggataag aaagctgtgg atttcatgtt
    23701 gggacaagcc tatttcatgc gtgcctatat gtattattgg atggtgttgc atcatggtgg
    23761 cgtaccttat ttgaaagtgc cgcaagataa agataaggat gatttgtacg tgaaacgtaa
    23821 ctctacgccg gaatgtttcc agtttatgat agaggattta gatcatgcga tttccttgtt
    23881 gcctgccaaa atagctggta gttccagtga ttatgggcgt atagaccagt gttttgcaaa
    23941 gtcttggaaa gcaaagacct tgttactgaa agcttctcct cagttcaatc cgaaacgtat
    24001 gtatgataac gcatactgga aagaggctta cgtggcggct aaggaggcgt atgatttttg
    24061 tgtgcagaat ggcatcgcgt tgacagagaa tccggcggat atttggttgc aagaaagagg
    24121 tccggaggtt atcttcccgg ttatttattc aaatccgaac cgtgtcgcta cttgggagta
    24181 tggtacgcgt ccggcttctg tgagccgtga taaaccttat cataatccta cttgggaatt
    24241 cgtaaaggat ttcccgatgt tggatggtaa gcgttacgac gatcctacgg gcaagtatta
    24301 cgtaggtgac gagcaggctt tgctgaaggc tttctggaag aatcgcgatc cgcgtttcaa
    24361 cagggcttgt ttgtataacg gacgcgaatg gccggtagct ggtagatctg ccgacaaccg
    24421 tatgtataac gccttgggtg tgagcaacgc agacgatcaa tatggtgtca atccgaatgc
    24481 gggtgtcaat gcggccaaca atgatatttt ctctggaatg tataattaca aagtgtctga
    24541 tctttccttg acacaagaca aggtgatgac gttcgatatt gattatatct tgatgcgctt
    24601 tgccgaagtg atgttcatct atgcggaggc cgctaatgag aacggacatt ctgatgtagc
    24661 tatcgatttg ttgaaacaga tccgtaagcg tgcgggtata gaggcagggg cggatggttt
    24721 gtatggcttg aaggttggta gccgtgagga gatccgtcag gcgattttgg atgaacgtca
    24781 tatcgagctg tgctatgagg gacatcgttt ctgggacttg cgccgtacgc gtaatatgat
    24841 gatgttggcc ggttggacga aacatggtat cgaggcgatc gcagtcaacc cggatggctc
    24901 ggatatggac ttgaacgtcg ctcgcgaccg gatcgccaag aatgagttga ctaccggtga
    24961 ttttcgctac gtaatccatc aagttcctta tacggaggca gctgagcgcc agttcgtgat
    25021 cgaggaaagc ttctatttct tcccgatcaa gaaaacttac ttggacgaga acccgaattt
    25081 ggagcagaat aataattggg gaggtacgtt caatccgact atggaacaat aattgattga
    25141 ttcttagatt gaataataag gaatatgaac attaggaaat atatatgggc gtacgtggtg
    25201 gctatggcct tgatttgtcc gggcgtgaag gcgcaggaac agatcacgat cggtgtcatc
    25261 caatatgatg tacgcgatat agataagagt ttcaaagccc tgcatgagca gggctttggt
    25321 tcttgtgagt taaattatag tgaaaaaaga ttcacgaagg aattggcgga gcaggtgaag
    25381 gccgcttccg agaagcaccg gatccgggta actacgttgg ttggtgtgcc gggaagtaaa
    25441 agtacgtgga attttcgtca aggaccggct acgatcggcc tggtacctat cgatgagcgt
    25501 ttcgagaagt tggacttata ccgtaaaatg atcgattttt gtgtacaggc tggtattccg
    25561 gctatgcact cgcattttgg atttattcca gaggatccgt cttcggcgca gtataaggat
    25621 ttcattgagg tgatgcgtgg cttggctact tatgcgaagg agcgtaatgt cttgatttat
    25681 ttcgagactg ggcaggagac accaatcact ttgattcgtg cgatccggga tatcggtacg
    25741 ggtaatttgt ttatcaattg tgatttggcg aatttactaa tgtatggcaa gtcgaactcc
    25801 ctggatgcgg tcaagttgtt tggtaacttg attaaagagt tccatgcgaa ggatggcaag
    25861 tatccggatc ctaacaatcc gtatgagctg ggccatgagg taccgatccc tacgggcgat
    25921 gtagattttc ccgcagtgat tgccgagttg aaaaaacaag gattcaaggg tgcgataaca
    25981 attgaatgtg agctgaatgg tacccgccat gattatgtga tccaaactcg taaatatttg
    26041 caagagttgc tggatcgata ggccgcttaa tcacgattgt aagcggtgtt gaatgcccat
    26101 tgtaagtgct ttataatgcc cattataaag agcctgcaat gggcattgtc gtatttgtaa
    26161 gaattatcga caggagttgt tattttatta gagggaaaaa attatctttg cgtgtatact
    26221 gtctaattgt taaaatagag gataatggaa gagaagaaaa gattgactcg ttcgaataat
    26281 aagatgatag ggggtgtttg tgccggtctt gcggaatact tggatatcga tccgacgatc
    26341 gtacggatcg tatgggtatt gatggttctt ttcgccggat tcggtatact gctctacatt
    26401 atattatggt taataatgcc taaacaacag atcgggtaaa ggatgaattt tgaaatatcg
    26461 tcttcgttca gtcccacggg tgaccaaccc gaggcgattg cggcgttgtc ggaagggatc
    26521 aagagtggtg ttcctttcca gacacttttg ggtgttaccg gttccggtaa gacgtttacg
    26581 atcgctaacg tgataaagga agttcagaga ccgaccttga tactcagtca taataagacg
    26641 cttgccgctc agttgtacag tgagtttaaa gcgtttttcc caaataatgc ggtagagtac
    26701 tttgtctctt attatgatta ttaccaaccg gaggcctatc taccttctac cgatacctat
    26761 atagagaaag acttggcgat caatgaggag atcgataagc tgcgtttgag ggccacggct
    26821 tccttattgt cgggtcgtaa ggacgtgatc gtggtctcat ccgtatcctg cttatatggc
    26881 atggcagacc ctacggcttt cgccgagaaa gtgacgcatc tggaacgggg tatgcgtatc
    26941 gaccgggata agctgttgcg ccggtttgta gacgccttgt acgtgaataa taagctggag
    27001 ttcaaaagcg gctgtttccg tgtgaatggt gatacggtgg atattttccc ggcgatcgag
    27061 accttcgacg gcatggcgta ccgtatcgag ttctgggatg atgagataga ccgcatctcc
    27121 tctttcaatc cgttgacagg cgaggagtat gatgagcaag atgagctgaa tatttatcct
    27181 accaatttat tcgtgaccac ccaagagcgt atcaatatgg cgatcggtca gatcgatgtg
    27241 gatctgggga cgcaggtgaa tttcctcaag gagatcggta agcccttcga ggcgaaacgc
    27301 ctgtatgagc gtgtcacgtt tgatctggaa atgatccggg agctagggca ttgctcgggt
    27361 atcgagaact attcccgtta tttcgacgga cgcgcggcgg gagatcgtcc tttctgcctg
    27421 ttggactatt tcccgaaaga cttcctgctt gtcgtagacg agagccatgt gacgatcccg
    27481 cagattcgtg cgatgtatgg cggggattat gcccggaaga aaaactt
//
LOCUS       DBMDTB010000050        27166 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_640_length_27166_cov_10.003325, whole genome shotgun sequence.
ACCESSION   DBMDTB010000050 DBMDTB010000000
VERSION     DBMDTB010000050.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 27166)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 27166)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27166
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_640_length_27166_cov_10.003325"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(103..600)
                     /locus_tag="ACZPB4_09425"
     CDS             complement(103..600)
                     /locus_tag="ACZPB4_09425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HIR1098471.1"
                     /translation="MALNYSVSLRTNPIKKDEPAKAYATAQINGELSLKQLSRRVSMQ
                     TTVSRADVVAVLISTVENLLDALQEGKQVDFGELGKFRLHILNEGAESLEKFTSTNIT
                     GVSIQYIPGEDLKNVFAGLEFQPVATRKAQQAVLRAEKAGETTVDISKKPAAGGGDSE
                     SPDEI"
     gene            830..1012
                     /locus_tag="ACZPB4_09430"
     CDS             830..1012
                     /locus_tag="ACZPB4_09430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4248 domain-containing protein"
                     /protein_id="HIR1098472.1"
                     /translation="MRTGYTQIDEWPVRPYSKRELAMAYAPEISPVSALNRLAEWMRY
                     NDRLTRELGDTGYRPR"
     gene            complement(1203..3035)
                     /locus_tag="ACZPB4_09435"
     CDS             complement(1203..3035)
                     /locus_tag="ACZPB4_09435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3987 domain-containing protein"
                     /protein_id="HIR1098473.1"
                     /translation="MNPLSDLERLVAAIEHQGANIAPTYQEYMPIAFATANDCGEAGR
                     TFFHRICRLSEKYVYEEADKLYDHALKAGNGRNGLGSVFHWAEIAGVKTDKQLADTFR
                     QYLRENKNPSNLQAPLTPTHAHTYAREDLPPAFPDYPWPPFIKQMIDCGNSIAQRDIL
                     LLGVFTVLGGTLNKRVRVLYGQKYMYPCLQTFIVAPPASGKGALTWVRRLAEPIHEEL
                     MARYKDSLKNYREEKNRWDSLGKKRSETPEPEQPPLKMFLIAGDNSGTGILENLIEAD
                     GVGLICETEADTVSTAIGADHGHWSDTLRKCHDHERLAFNRRTNHEYRECDESYLSVL
                     LSGTPAQVKPLIPSAENGLFSRQLFYFMPPINEWMDQFDSESEDYGLRFATWGTQWKQ
                     VLDLINGSVQTIQLKLSEKQKELFNQRFAQLFSHAGYAHGGSMRSAVARIAINTCRIL
                     SIVALLRALEKFLPPQQKIFNSQFSIFNSPGLSPAPEIPIENIKDGIVPKLDLRVTDE
                     DFQAVLTLIEPLYRHSSYVLGFLPTSEAVPVQTSPEQALFNALPMMFCRRQAVDVAAK
                     NGIPEKTLDSSLKRMLEKGTLIKTARGEYAFSSHVCVRERRPKE"
     gene            complement(3091..3654)
                     /locus_tag="ACZPB4_09440"
     CDS             complement(3091..3654)
                     /locus_tag="ACZPB4_09440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BT4734/BF3469 family protein"
                     /protein_id="HIR1098474.1"
                     /translation="MKECIMSFFNAPISNQVPSGVTSVKQLHTYITSNEWLKERTLSV
                     QDALSDEKRFRKLKQNLLPYVTPAGVFSYRKEDRLLFLSGEFVIDIDHLPSPEETLHW
                     RDTLFADNKLRPDLAFVSPSTTGVKLLVPYRLSPKASIEESFDKARLSAWEYLKWKYG
                     LNADASNADLSRACFLCHDPSAKLRES"
     gene            3792..4220
                     /locus_tag="ACZPB4_09445"
     CDS             3792..4220
                     /locus_tag="ACZPB4_09445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098475.1"
                     /translation="MSEEKASPCVLHIHGENIQVLPNAMFAIQYICLDPGEKPEVVSE
                     KDVRPDPEPCDLLASYIQDEEVRHDFVKRIAQCPDVATLCQTVLTDLFNEVFCDCVEP
                     AKLIKSKEFINAIIPLLPFKQGKSLRNIRRAIVKYVLGEG"
     gene            4290..4583
                     /locus_tag="ACZPB4_09450"
     CDS             4290..4583
                     /locus_tag="ACZPB4_09450"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HIR1098476.1"
                     /translation="MKSRQEILALLRDFKVRKGKKYGILKMGIFGSVARDQQTESSDV
                     DIYYEGEAQGLFSLSHLKNELEELLGSPVDIIRLRDRMNQLLRKRIEREGIYV"
     gene            4576..4950
                     /locus_tag="ACZPB4_09455"
     CDS             4576..4950
                     /locus_tag="ACZPB4_09455"
                     /EC_number="3.1.27.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HepT-like ribonuclease domain-containing
                     protein"
                     /protein_id="HIR1098477.1"
                     /translation="MFDTELALDTLSQIKDTLSMIMARTSHIHKVDDFYMNESGMILL
                     DSVCMKLVAVGEALKNLDKITNKELLLKYPAVNWKDIKGMRDIIVHHYFDIDASVILY
                     SLQKEVPDLYSTICVMLRDLSR"
     gene            5170..6717
                     /locus_tag="ACZPB4_09460"
     CDS             5170..6717
                     /locus_tag="ACZPB4_09460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0140327 - flippase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HIR1098478.1"
                     /translation="MVTDSRTSKSIKNSSVALAFYFINLVLQFFSRKVFLDYLGAEIL
                     GLNTTATNLLQFLNLAELGIGSAIACTLYKPLLEKDTVAINEIVSLQGWLYRRIAWIV
                     IVGSLVLMAFFPWIFAKMPLPLWYAYASFGVLLVSALLSYFVNYKQIVLSADQKEYKI
                     QYSYKASMLIKTLCQILAIRYLRDGYVWWLVLEIVFAIVASLVLNRMVRQTYPFLETK
                     LGRGRELSRKYPAIIKKVKQLFFHKIGSFALTQTSPIIIYAYTTLTVVALYGNYMLVI
                     LGIQTLMTAIFNSMNAGIGNLVAEGNRKQIMSVFEELFSVRFLFTCIMCFGVFMLTPL
                     FIILWVGNEYVMDTMTLLLMTVTLFIQLNRTTVDAYINAYGLFGDIFAPVTEASINIC
                     LSVLLGYFWGLNGVLLGVLISLFLVVFCWKPYYLFRKALKQRLKLYIIMYVKHLSVAI
                     VSIILIYFVLKFVPMHSFESALSSFVYGVFITILYTLILLSMFYFLGLGLNRFIRRIQ
                     SMMNGRK"
     gene            6818..7756
                     /locus_tag="ACZPB4_09465"
     CDS             6818..7756
                     /locus_tag="ACZPB4_09465"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HIR1098479.1"
                     /translation="MTPVISIIVAVYKAESCLRRCVDSLLAQTFQDYEILLVDDGSPD
                     RSGEICDEYARKDNRVRVFHKENGGVASARQCGMNNARGEYVIHADPDDWVEPNMLEE
                     LYGKAKEENADMIICDVWRDTSKKSTYVKQRLFILEHCVMLKDVFQQLHGSCCNKLVK
                     RACYSKYDVNFPEGLSYGEDTYVSVCLLAHPIKMAYVPKAFYHYVQNVNYSSLTRRPV
                     KILVEQCEKLCDLLRCKLSENQFKEIYPALRYRQACVILTSAGENPYIVTFKKDFEGV
                     RKAILHQNFSFKRKTLFWIAFYISPYIAHFFYTFCR"
     gene            7803..8984
                     /gene="wzy"
                     /locus_tag="ACZPB4_09470"
     CDS             7803..8984
                     /gene="wzy"
                     /locus_tag="ACZPB4_09470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide repeat unit polymerase"
                     /protein_id="HIR1098480.1"
                     /translation="MSDVSRIDTYGAKLVLLPYMLAIIGSCLYTIILGVYNGDFIQRD
                     VLFPLPALLVIAVLTIIPYIGIYGLYKRYRSKETENVPDKFKVAIIRNITWLLLLVHI
                     GLLFTGYGQMGTSIEIDGGFFSYIRSAFFKLMVRPWVIAYLLISNSRKNLAVTVLLFS
                     IHTILAHSLGGFFILLLILLFRQGKKVKSFVKRNFLFVLAILYLVPIVVSSAYNVRAQ
                     LRGQGGMSETSNMDIMVGKLCGRISSFSNSAYILQNSSQNVYDLELIPDFFYFYDTLH
                     YWGYRPEFKSTGFYVEEQIKHSKLENSSTMPGVIGVLIMSYVKSPYIFLFNLFLMTFL
                     LIIIFNLTKRIGFPNASGIAYILTIEFATSGDISALSNTIYTLLIIWFTLSISNIIIW
                     K"
     gene            8975..10057
                     /locus_tag="ACZPB4_09475"
     CDS             8975..10057
                     /locus_tag="ACZPB4_09475"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009101 - glycoprotein biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HIR1098481.1"
                     /translation="MEMKKKKKVLVLYPSGNYLYPTTGGELYDSYLFKRILFSGQIDM
                     SFFTKDHTRRINKWLLPAYILWSCRRIGSYDAVFLNSGWFAQSIWLLYFFRIFYPKLK
                     VYVIHHHFRYQEMSGIKRQLQYMLEWLGLGVSFAIITPNPYTHSLIKQMRPDSRTVFL
                     EMAFKKDVPTCSCYVLKQLLFVGTVYQRKGLLYLLEAIGQMSEKERSGIHLDIVGDLS
                     QKKYYKCLLSLVHLYGLEDIVTFVGRISDEELRSYYSRAYCFVFPSLLEGYGMVLIEA
                     MSYGLPVIAFDNSAIPFTVKNDRNGILVRNKSILDLKKAILKLCVDTDYHRKLCDGAL
                     DTYRNARSLSDLDIDIENFVIKELIN"
     gene            10507..11400
                     /locus_tag="ACZPB4_09480"
     CDS             10507..11400
                     /locus_tag="ACZPB4_09480"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009101 - glycoprotein biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HIR1098482.1"
                     /translation="MTIATKYSEIDWSADVIFVWWWTYAFFPVFVSKLLRKKVVITGT
                     FNYKCPMVASDYYRRPLLERLLIKFSIKYANENILVSRNEYEQIYKDWNLKNIVYSPH
                     CIDTVKYSRGMYCNRGNELFTICWTGKENVKRKCLYEIIDSVELLKDKLDMHLNIAGH
                     KGDAFDEVKKYISEKGLNAYISILGEISEKEKLCYLKSCRFYLQPSRYEGFGLAIAEA
                     MSCGTVVVTTDVGEVLNVVGNAGIIIRNTLPETIANVIEDYWNNDLESISIAAHSRIE
                     TLFSMARREKDIMNVVKKYKE"
     gene            11403..13520
                     /locus_tag="ACZPB4_09485"
     CDS             11403..13520
                     /locus_tag="ACZPB4_09485"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bi-domain-containing oxidoreductase"
                     /protein_id="HIR1098483.1"
                     /translation="MKQIIQDIKSGRTVLEEVPVPQVRAGYVLVKTSRSLVSLGTERM
                     LVEFGKANLIDKARQQPDKVEQVLDKIKTDGLQPTLEAVFNKLGQPLPLGYCNVGRVV
                     AVGKGVAEFKVDDRVASNGNHAEFVCVPKNLVAKVPDDITDEEAAFTVIGSIGLQGIR
                     LLNPQLGETVVVVGLGLIGLVAAQLLRANGCKVIGVDFDQQKVDMAASKGIVAVNPGK
                     GTDPVRFVEDYTGGIGADGVLITASTQSHEVIHQACEMSRKRGRIVLVGVIGLNMRRD
                     DFYKKELSFQVSCSYGAGRYDEEYENKGHDYPLAYVRWTEKRNFETILHAISSGSLDV
                     KSLITEEVDLVDYEEIYGDMRKKGSIASILRFPADSKMESVVSIGNNTFVSGKGKIGI
                     IGAGNYTSAMVIPCLAKAHARIKYIASAQGLSAKILARKAGAENATSDYQNILKDPEV
                     DLVMVTTRHNLHARMVIEALRNGKSVFVEKPLCLNETELDDIIRAYQGAPEGTTLTVG
                     FNRRFSPFAEKMKRLLGDGPKNIVATMNAGFIPQEVWVHDLEIGGGRIIGEACHFIDL
                     CSFLAGSEVVAVCMNALGENPEENTDNASILLRYANGTNAVINYFANGSKSYAKERVE
                     VFSQERVLVLDNWRKLTGYGFKGFSSMKAGMDKGQKRQFTLLNERIREGGKPLIPFGS
                     ILNTTKATFACITSLKERCWVNL"
     gene            13502..15088
                     /locus_tag="ACZPB4_09490"
     CDS             13502..15088
                     /locus_tag="ACZPB4_09490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heparinase II/III domain-containing protein"
                     /protein_id="HIR1098484.1"
                     /translation="MLGESLKLYISTLRNLRSRQVRYQVWYRLRAYIRKYRSFRYVLS
                     LPRVGHPLSFKLFISKYTDLDSVTGHFSFLGKESAFLGWNDESFGKLWSYNLNYMDYL
                     HQETISFEQAVCWIDKFVDEIEGNRNGLEPYPIALRGINWIKFLSKYHPYIPAENKRE
                     WDSSLYAQYKILLDNLEYHLLGNHLLEDAFSLLWAGLYFKDESIYQKAKDLLFKELEE
                     QLLPDGAHYEQSPMYHCILLDRLLDCYNVSMNNLRFIGQEGLNERLREKASSMLGHLA
                     SVVYKDNTIPLLNDSAEGIAPSPTQLFAYAKRLDMDWEKLPMEACGYRKLMAGHWEAI
                     VDVGDIRASYQPGHSHADMFNYELRIGGKLFVIDTGISTYEKTARRQYERGTAAHNTV
                     MIGDKNSSEVWGGFRVGRRARVTLLKDSPNEVEAWHDGFGSLGRHRRKFTIDKDCFRI
                     EDSVSTGVKAVSLIHLAPDVEIMSCSRTEIVTNIAAIRVAGASSVEIVDDQVSFTYNR
                     FHLSKTIRIHFVKRLSYTIG"
     gene            15150..16355
                     /gene="wecC"
                     /locus_tag="ACZPB4_09495"
     CDS             15150..16355
                     /gene="wecC"
                     /locus_tag="ACZPB4_09495"
                     /EC_number="1.1.1.336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_function: GO:0089714 - UDP-N-acetyl-D-mannosamine
                     dehydrogenase activity [Evidence IEA];
                     GO_process: GO:0009246 - enterobacterial common antigen
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetyl-D-mannosamine dehydrogenase"
                     /protein_id="HIR1098485.1"
                     /translation="MKACFMGLGYIGLPTAIIAAKHGVDIAGVDINAQVVEVTNQGKL
                     HIIEPGMEEMLREVLASGHFKAYTEPRVSDAYFMVVPTPFKGDHEPDVSFVESATRMV
                     LPLLKEGDLYVIESTSPVGTTERMASLIFSERPELEGRIYIAYCPERVLPGNVIHELV
                     HNDRVIGGMDEASTRKAMEFYGQFVKGTLHPTNSKTAEMCKLTENSSRDVQIAFANEL
                     SFICDKAGINVWELIDLANRHPRVNILQPGCGVGGHCIAVDPYFITAEFPMESRMIST
                     ARETNNYKAFWCAEKVRNAMLRFELKHGRKPAVAMMGLAFKPDIDDLRESPAKGITTK
                     VLQSCNNADIMVVEPNVSEHKLFKLTPYKEAYEKADIVVFLVNHREFAGLNYRDDVEV
                     LDFCGTFKK"
     gene            16381..17541
                     /gene="wecB"
                     /locus_tag="ACZPB4_09500"
     CDS             16381..17541
                     /gene="wecB"
                     /locus_tag="ACZPB4_09500"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008761 - UDP-N-acetylglucosamine
                     2-epimerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="non-hydrolyzing UDP-N-acetylglucosamine
                     2-epimerase"
                     /protein_id="HIR1098486.1"
                     /translation="MRKIMLVFGTRPEAIKMAPLVKEFQKHPESFETIVCVTGQHREM
                     LDQVLKLFEITPDYDLNIMRQGQDLYDVTARVLVGMRDVLREATPDVVLVHGDTTTST
                     AAALAAFYQQIPVGHIEAGLRTHNIYSPWPEEMNRQITGRIATYNFAPTRLSKQNLMR
                     EDVNPDSILVTGNTVIDALRQVVRKIKTDAELDKELEGVLLRSGYDVNRLVEGKRLVL
                     ITGHRRENFGDGFIHMCTAIKDLTRKYPKVDFVYPMHLNPNVRKPIHEVFGEDLSHLE
                     NMFFIEPLEYLSFVYLMEKSTIVLTDSGGIQEEAPGLGKPVLVMRDTTERPEALAAGT
                     VKLVGTDYDKIVSEVSALLDDTAYYDAMSKAVNPYGDGLACGRIVEFLNRKE"
     gene            17538..18059
                     /locus_tag="ACZPB4_09505"
     CDS             17538..18059
                     /locus_tag="ACZPB4_09505"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family protein"
                     /protein_id="HIR1098487.1"
                     /translation="MRVLIVSPSYLPEIGAAPSRITNMAEGLSGLGIKVDVLTCLPNY
                     PKGRIFDGYRGAFSKTEDVNGITVFRYWTYASISRRPLVRLASMCAFATTLWCFALKR
                     KRIKSYDKVIIQTPPVLAAASAMLLFRCCYRKKVVLNVSDLWPLSAVELGAMKEGGVY
                     HGVMGPYRAFPLS"
     gene            18094..18729
                     /locus_tag="ACZPB4_09510"
     CDS             18094..18729
                     /locus_tag="ACZPB4_09510"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012744.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HIR1098488.1"
                     /translation="MDYIKRYEPGKASFLYRNLQHRFVLPNQPPSSRKPFRIVYAGLL
                     GVAQNILELIERIDFKGMGAELHLFGGGNQALEIEDYVRTHDKGVFYHGSLPKERMRE
                     ELTRYHASIIPLTVRIRGAVPSKLFDLLSLGVPILFCGGGEGEEIVKENQLGLVSAPG
                     DYERLSKNIRAMSHLPDEEYRQLKANCLRLSQTTFCFERQLEAYKRFLSAF"
     gene            complement(18925..19386)
                     /gene="ndk"
                     /locus_tag="ACZPB4_09515"
     CDS             complement(18925..19386)
                     /gene="ndk"
                     /locus_tag="ACZPB4_09515"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008150491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004550 - nucleoside diphosphate kinase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HIR1098489.1"
                     /translation="MEKTLVILKPCTVQRGLIGEIVTRFEKKGLRLAGMKMVWLTDEI
                     LSEHYAHLKEKPFFQRIKDAMSVCPVIVCCWEGVDAIHVVRTLAGATNGRNAAPGTIR
                     GDYSMSVQENIVHASDSPETAEIELKRFFKDDEIFDYELKNLLSLYANDEF"
     gene            complement(19611..20240)
                     /locus_tag="ACZPB4_09520"
     CDS             complement(19611..20240)
                     /locus_tag="ACZPB4_09520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="master DNA invertase Mpi family serine-type
                     recombinase"
                     /protein_id="HIR1098490.1"
                     /translation="MVYGYVRVSTDKQTTENQRFEIEKFTKSRNMRIDRWVDETISGT
                     KVIADRQLGKLLKQIRKGDILITTELSRLGRNLMQVMSFLHQCMERDIIVFTVKEGYE
                     LGNNINSKILAFAFSLSAEIERNLISQRTKEALARKKVQGAKLGRPKGERPETCKLKG
                     KEEMILQYIKEHKTKVYISKKLGVNRQTLREFLKTHPEIPRKWKRIQKD"
     gene            20386..23298
                     /locus_tag="ACZPB4_09525"
     CDS             20386..23298
                     /locus_tag="ACZPB4_09525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_function: GO:0016772 - transferase activity,
                     transferring phosphorus-containing groups [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional fucokinase/fucose-1-phosphate
                     guanylyltransferase"
                     /protein_id="HIR1098491.1"
                     /translation="MDIRIENLSYFCFRKIRWSLRMIMGMKKLLSLPPNLVDCFHAVE
                     HVSTEEWFCTSDPVGARLGSGGGTTWLLEASRQKEAPDVPTEEWLGQEKRILLHAGGQ
                     SRRLPGYAPSGKILTPIPVFRWARGQRLSQNLLSLQLPLYERIMKKAPESLHTLIASG
                     DVYIRANQPLQEIPEVDVVCYGLWVEPSLAKNHGVFVSSRKSPDTLDFMLQKPSLETL
                     GELAGSHLFLMDIGIWLLSDKAVRLLMKHSYTEDGKAMKAYDLYAEFGLALGKNPRIT
                     DSELNQLSVAILPLPGGEFYHYGTSRELISSTLAVQNLVRDQRAIMQRKVKPHPAMFV
                     QNAVLHQKLTAENSELWIENSYIGENWTLRGQQIITGVPENNWNLSLPEGVCVDVVPV
                     GEANWAARPYGFNDLFKGALSDVSTLFMGKPILTWAMERGITLGGNEDIQNAPLFPIC
                     QTVDELGKVLRWMITEPDREEGKFIWLSARKLSANDLSDQANLRRLVAQREVFRKKDW
                     SLLAANHEKSVFYQLDLSDAAESFAKDKIVLPKALPEDNPLMKRIHNHMFRSQVMKIS
                     GVAYKEEEQKAFALLREGLVGSVLGSKQQPCLNVYRDQIVWGRSPVRIDLAGGWTDTP
                     PYCLYAGGNVVNVAIELNGQPPLQVYIKPSDTHKIILRSIDLGAMEVISSWDELRDYN
                     KVGSPFSIPKAALALAGFIPEFSAEAYASLDVQLEAFGSGLEITLLAAIPAGSGLGTS
                     SILAATVLGAISDFCGLAWDKNEIGNRTLILEQLLTTGGGWQDQYGGVLHGLKLLQTN
                     EGFNQNPLVRWLPEYLFTDPEYRPCHLLYYTGITRTAKDILSEIVRGMFLNSEAHLGL
                     LSEMKAHALDMYEAIQCGDFVTYGKLVGKTWEQNKALDSGTNPVAVEAIISKIQAYAL
                     GYKLPGAGGGGYLYIVAKDPGAALQIRKILTLSPPNSNARFVEMSLSNKGLQISRS"
     gene            23521..26079
                     /locus_tag="ACZPB4_09530"
     CDS             23521..26079
                     /locus_tag="ACZPB4_09530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5686 and carboxypeptidase-like regulatory
                     domain-containing protein"
                     /protein_id="HIR1098492.1"
                     /translation="MGKRIVFIWLLLAFAWVAKSQNYMIKGIVTDSITGEPLPYVAVI
                     LKGTTIGATTDLDGAFTLSSSSKVRTLQVSYLGYTEKELKFVPGKAEHLKIQLAPTSI
                     NLSEVIIKPGKERYRKKDNPAVTFIKNAIARRESNDPHNHDYFRYDQYEKMVFAMNDY
                     QPKPKKDGKAGKFDFLTEFIDTLEVGKTILPVSEREKIQTVYYRKDPKTEKRVVLATK
                     AAGVDEVFSRDGMQQFLNEVFREVNIFQNDIPLFLNRFVSPMSTMGPNFYKYYLLDTV
                     EVAGQKCVDLGFAPFTPETFGFTGHLFITLDSTYFVQKVKLNVPKKINLNFVGGMTIE
                     QTFDRAPDGTRIITKDDINVDFKLTEKSKGMYARRLNIYSNQAFEGPDDPKVFEESAP
                     IIIPMEAYRRSADFWEENRPTEAGTRKQNNVELLMAKLRSVPIFYVTEKVVSILTSGY
                     IATNKIPEKSKFEFGPMNTYISGNAIEGARFRVGGTTTTAFSKRLFLDGYLAYGSKDR
                     KLKYDGIVEYSFIDKKDYRKEFPVHSIRFEYLYDINQLGQQYMYTNKDNMFLALKRQK
                     DTRATYLRNMELTYYREHYNGWAYGAVLRNFKEYSTGYAAFDRIGPDGQITATDSYRM
                     SEVEFKFRFAPNEKFYQTRNYRYPITLDAPVFTLNHTMAFQDVLGSSYDYQKTELGIQ
                     KRFWFSAFGYVDILAKAGKVWTKAPYPLLILPNANLSYLVQPESYTNMNAMEFINDEY
                     ASWDITYFMNGALLNRIPLIKKLKWREVFSFRGMFGHLTDKNNPYIGEQNEGLFLFPQ
                     GSYLMDPSTPYMEAGVGIENIFKFLRLDYVWRLTYKDHPGIQTKGIRFMMKLSF"
     gene            complement(26094..27164)
                     /gene="dinB"
                     /locus_tag="ACZPB4_09535"
     CDS             complement(26094..27164)
                     /gene="dinB"
                     /locus_tag="ACZPB4_09535"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008768057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HIR1098493.1"
                     /translation="MIHIDMDAFYASVEQRDNPELRGKPLAVGHAEQRGVVAAASYEA
                     RKYGVRSAMASQKAKRLCPNLIFVHGRMDVYKSVSRQIHEIFHDYTDIIEPLSLDEAF
                     LDVTDNKRGISLAVDIAKEIKKRIWDNLNLIASAGVSYNKFLAKIASDYRKPNGLCTI
                     HPSQALDFIARLPIESFWGVGPVTARKMHTLGIHNGLQLRECSGEMLTRQFGKAGMLY
                     YEFARGIDNRPVEAVRIRKSVGCEHTLEKDISRKSSVIIELYHVATELIGRLERSGFK
                     GNTLTLKVKFHDFNQITRSLSRPEELTTLDKILPLAKELLKEVEYTEHPIRLIGLSVS
                     NPVKEEPHTKDRWEQLSFEFSD"
BASE COUNT         6987 a         5111 c         7053 g         8015 t
ORIGIN      
        1 cgaagcgagt tgggatgcga cagcgagcgt aggtctcgaa gtagcccgtc agcgtcagcc
       61 ttgacctttt ggttactttt gggtcaagcc aaaagtgaca cgttagatct catcaggcga
      121 ctccgaatcc ccacccccag cagccggctt cttcgagata tccacggtag tctccccagc
      181 cttctccgca cggagcaccg cttgctgagc cttgcgagta gccacaggtt ggaactccag
      241 cccggcgaag acattcttca agtcctcgcc cggtatatac tggatactaa ccccggtgat
      301 gtttgtagat gtgaatttct caagactctc cgcaccctcg ttgaggatat ggagccggaa
      361 tttacccagt tcgccgaaat ccacctgttt cccctcttgg agggcatcga gcaggttctc
      421 gacagtggag atcaataccg ccaccacatc cgcccggctg acggtggttt gcatggatac
      481 ccggcggctc agctgcttga gcgatagctc accattgatc tgtgccgtgg cgtacgcttt
      541 cgccggctcg tctttcttga tagggttggt ccgaagggac acgctgtaat ttaaagccat
      601 agatttgata attaaaaatt gataattgaa aattgaaaat gaaatcgatt tgttttcgat
      661 aacgaatgta cgacattcgg tttcctctga aatgaatacc gctgacagcg gatgaataag
      721 ggagataaaa gaggagatat gctgaaaaat aaacatccgt atagttgttc gtgtcgtgcg
      781 ttttaagtat ctttatacca ataagataaa tcttaaaaat gcgaacgata tgcgaacagg
      841 atatacacaa atcgacgagt ggcccgtgcg gccctattcc aagcgggagc tggccatggc
      901 ctacgccccc gagatcagcc ccgtctcggc cctgaaccgg ctggcggaat ggatgcggta
      961 taacgatcgg ctgacccggg agcttggtga tacgggctac cgcccgaggt aacgggtctt
     1021 cacctccctc caagtggagc tgatcttccg ttacttgggt cgtccttgag aggagacacc
     1081 gccacccgtc ggtataggcg agcggcgatg ccggtactgg catcagacaa cgccagtact
     1141 ggcgtagggc tgcgacggta gtgcttacgg gcgatgacag tagaggcatt tccttcattc
     1201 cttcattcct tcgggcgtct ctcacgcaca cacacgtgcg aggagaaagc gtactcgccc
     1261 cgtgcggtct tgatcagtgt tcccttctcc agcatccgtt tgagggagga gtcgagtgtt
     1321 ttctcgggta tgccgttctt cgctgccacg tccacggcct gccgacggca gaacatcatt
     1381 gggagggcat tgaataaagc ctgttcagga gaggtctgga cagggacggc ctcggaggta
     1441 ggcaggaagc ccaacacata gctcgaatgg cggtaaagag gctctatgag cgtgagtacg
     1501 gcttggaaat cctcgtcggt gacccgcagg tccagcttgg ggacgatacc atccttgata
     1561 ttctcgatgg ggatctccgg ggcgggggag agaccggggg aattgaaaat ggaaaattga
     1621 gaattgaaaa ttttttgttg gggagggagg aatttctcca aggctctcaa cagggctact
     1681 atgctcagga tccggcaggt attgatggcg atacgggcca cggcgcttcg catggaacct
     1741 ccatgggcgt aaccggcgtg ggagaataac tgggcgaacc gttggttgaa cagctctttc
     1801 tgtttctcgg atagctttag ctggatcgtt tggaccgatc cgttaatcag gtccagtacc
     1861 tgtttccatt gtgttcccca tgtggcgaag cgtaggccgt aatcctcgct ttccgaatcg
     1921 aattggtcca tccactcatt gatgggtggc atgaaataga ataactggcg agagaacagg
     1981 ccgttctccg ccgaggggat cagcggcttt acttgcgcag gggttccact tagcaatacg
     2041 ctgagataag actcatcgca ttcccggtac tcatgattgg tacgccggtt gaaagccagt
     2101 cgctcatggt cgtggcattt acgcaaggta tcgctccaat ggccgtgatc cgctccgatg
     2161 gcggtactca cggtatccgc ctcggtctcg cagatcagcc ccacgccgtc ggcctctatg
     2221 aggttctcta ggataccggt acccgagtta tcgccggcta tgaggaacat cttgaggggc
     2281 ggttgttccg gctcgggcgt ctcggagcgt ttcttgccga gtgagtccca tcggttcttt
     2341 tcctcccgat aattctttag gctgtctttg tagcgggcca tcagctcctc gtgaataggt
     2401 tcagctaggc gcctgaccca tgtcaaggct ccttttccgg aggcgggagg cgctacgatg
     2461 aaggtttgta ggcatggata catgtatttt tgtccgtata acacccgtac ccgcttgttc
     2521 aaggtgcccc cgagtacggt gaatactccc agcaggagta tgtcacgctg ggcgatggag
     2581 ttcccgcaat cgatcatctg cttgatgaac gggggccacg gataatccgg gaaagcgggt
     2641 ggcaagtcct cacgtgcgta cgtatgtgcg tgtgtgggtg tgagaggggc ttgaaggttt
     2701 gaaggattct tgttctccct caggtattgg cggaaggtgt cggccagttg cttgtccgtt
     2761 tttacgccgg caatctcggc ccagtggaag acggagccta atccgttgcg cccgttgccc
     2821 gctttgaggg cgtggtcgta tagcttgtcc gcttcttcgt agacgtattt ctcggacagg
     2881 cggcagatgc gatgaaagaa cgtccttccc gcttccccgc aatcgttggc ggtggcgaag
     2941 gcgatcggca tatactcttg gtaagtggga gcgatgttcg ccccttggtg ttcgatggcg
     3001 gcgacaagcc gctctaaatc tgataatgga ttcatttgat ttataagtta taatttatga
     3061 tttaaactgt caactgtcat ttgtcaacta tcaactctcc cgcaacttgg cggagggatc
     3121 atggcagagg aaacacgccc gtgagagatc ggcgtttgag gcatccgcat tcaatccgta
     3181 tttccatttc aggtattccc atgccgatag ccgtgcctta tcaaaagatt cctctatgga
     3241 agccttgggt gagagccggt aggggacgag cagtttcacg cctgtggtgc ttgggctgac
     3301 gaaagctagg tccggtctca gtttattatc ggcgaacaag gtgtctcgcc agtggagggt
     3361 ttcctccggc gaggggagat ggtcgatatc gatgacaaac tctccggaaa ggaataacag
     3421 gcggtcttcc ttgcgatagg agaagacccc ggccggtgtg acgtatggca gtaagttttg
     3481 cttcagtttg cggaaccgtt tctcgtcgct caaagcgtcc tgtacgctga gcgttcgttc
     3541 tttcagccac tcgttggagg tgatataggt atgcaactgt ttgacactgg tcacgccact
     3601 cggcacttga ttggagatgg gggcgttgaa aaaggacatg atacattctt tcattaactc
     3661 gtttgattta aagtttaggc tggtaaagga aaggtaaaag agtgagaaaa aacggtccgg
     3721 taagttattt gcacctatcg gtaagttatt tgcgcataaa agtaattcgg tgacaggaaa
     3781 aagaagaaga tatgagtgaa gagaaagcga gcccgtgtgt gctgcacatc catggcgaga
     3841 acatacaggt gctgcccaac gccatgtttg ccattcaata tatttgcttg gacccaggag
     3901 aaaagccgga ggtcgtttcg gaaaaggacg tgaggccgga tccggagccg tgtgatttat
     3961 tagcctccta tatccaagac gaggaggtgc gtcacgactt cgtaaagcga atcgcccaat
     4021 gcccggatgt ggccaccctc tgccaaacgg tgctgaccga ccttttcaac gaggtctttt
     4081 gcgactgcgt ggaaccggcc aaacttatca agagcaagga attcatcaac gccatcatcc
     4141 ccctgctccc cttcaagcaa ggcaagagct tgcgcaatat ccggcgggcg atcgtgaagt
     4201 atgtgctggg ggaagggtag gtgttttgat ttatgaatga ttgcataatt ggatatttat
     4261 ttgtttcttt gtcaatattc tattttctta tgaagtcgag acaagagatc ctagcgttat
     4321 taagagactt caaggttcgt aaaggcaaaa agtacggaat cttgaagatg ggtatctttg
     4381 gctctgtagc tcgtgatcaa cagacggaaa gcagtgatgt ggacatttat tacgagggtg
     4441 aggcgcaagg gcttttctct ctctcccatt tgaaaaatga attggaagaa ctgttgggaa
     4501 gcccggtgga tatcatccgt cttagagacc ggatgaatca gttgcttcgt aaacgaatcg
     4561 agagggaggg aatctatgtt tgatacggag ttggctttgg ataccttgtc gcagataaag
     4621 gatactcttt caatgataat ggcaagaact tcgcatattc ataaggttga tgatttttat
     4681 atgaatgagt ctggtatgat tttattggat agtgtttgta tgaaacttgt cgctgtaggt
     4741 gaggcactca aaaatctaga caaaataacg aataaggaat tacttcttaa atatccggct
     4801 gtaaactgga aggatattaa agggatgaga gatatcattg tccatcatta ttttgatatt
     4861 gacgcaagcg tgatacttta tagtcttcaa aaggaggttc cggatttgta ctccactatt
     4921 tgtgttatgc tgagggattt gtctcggtga cttatcacga taaatatagt ttaaactcat
     4981 tttaaatcaa gacactcgtt ttttgcccta ctggtttacc ggcgggatgg gagtggtttg
     5041 tgtacttgtc tttattccta gtaaatcaga gaataataag cggatagcga agaatacgct
     5101 gttcctctac gtgcgtatgc tctttatcat ggagagcaat ttttgtatta aacacaattc
     5161 tttgtagcaa tggtaacaga ctcacgaact tcgaaaagta taaaaaatag ttcggtagcc
     5221 ttggcttttt attttattaa tctggttctt caatttttct cccgtaaggt attcttggat
     5281 tatcttgggg cagagatctt gggactgaat actacggcta ccaatttgct tcagttcttg
     5341 aaccttgcgg aattaggaat aggatcagcc attgcttgta cattatataa gcctttatta
     5401 gagaaggata cggttgctat caatgagatt gtttccttgc aaggctggtt gtatcggcgt
     5461 atcgcatgga tcgtgatagt gggaagtctc gtgttgatgg cgtttttccc ttggatcttc
     5521 gctaagatgc cgttaccctt atggtatgcg tatgcttctt tcggagtgct gctagttagt
     5581 gcattgctga gttattttgt taattataag cagatcgttt tatccgctga ccagaaagag
     5641 tataagatcc agtatagcta taaggcctcg atgttgatta aaaccctttg tcagatattg
     5701 gcgattcgat atttgagaga cggttatgta tggtggttgg tattggagat tgtgtttgcg
     5761 atcgtagctt cgttggtgtt aaatagaatg gtccggcaga cttatccatt tctagaaact
     5821 aaattaggac gaggtcggga attatcgaga aagtatccag ctattattaa gaaagttaag
     5881 caattgtttt ttcataagat cggtagcttt gctttgacac aaactagccc gatcattatt
     5941 tacgcctaca ctacactaac tgtagtggcg ttatatggca attacatgtt ggttatcctt
     6001 gggattcaaa ctttgatgac tgccattttt aatagcatga acgcaggaat tgggaattta
     6061 gtggcagagg gaaatcgtaa acagattatg tcggtgtttg aggaattatt ctcagttcgt
     6121 tttctattca cttgtataat gtgttttgga gtgtttatgt tgactccttt atttataata
     6181 ctttgggtgg gtaatgaata tgtgatggat accatgacat tgctattgat gactgttact
     6241 ttgtttattc aattaaaccg tacgaccgtg gatgcttata tcaatgctta tggtttgttt
     6301 ggtgatattt ttgctccagt tacggaggct tctatcaata tctgtttgtc tgtgttatta
     6361 ggatattttt gggggttaaa tggtgtattg ttgggtgtgt tgataagttt atttcttgtt
     6421 gttttttgtt ggaaacctta ttatttgttt cgaaaagctt tgaaacaacg attgaaattg
     6481 tatataatta tgtacgttaa gcatttaagt gttgcaattg ttagtataat acttatttat
     6541 tttgtattga aatttgtccc aatgcactca tttgaaagtg ctttatcttc ttttgtatat
     6601 ggagtgttta ttacgatttt gtatacactc attcttttat ctatgtttta ttttttagga
     6661 cttggtttga atcgctttat tcgaagaatt caaagtatga tgaatgggag aaaatagtat
     6721 agtgatatat aggttgtatg atacattaaa aagttagcta agataggctg tatggtttat
     6781 aatattcaaa gtaaaaaatg tttaataaat ataacaaatg acacctgtaa tttctattat
     6841 tgttgctgtt tacaaagcgg aatcctgctt gcggcgttgt gtagacagcc tgctagcaca
     6901 gacttttcaa gactatgaaa tattgctggt agatgatggg agtcccgatc gttccggaga
     6961 aatttgcgac gagtatgccc ggaaggacaa tcgtgtccgt gtattccata aagagaatgg
     7021 tggagtagcg tccgctcgac agtgtggaat gaacaatgca agaggcgagt acgtgataca
     7081 cgctgaccca gatgactggg tggaaccgaa tatgctggag gaactatacg gaaaggcaaa
     7141 agaagaaaat gcagatatga taatttgtga tgtatggcgg gatacttcca agaaatctac
     7201 ttacgtgaag caacggttat ttatattaga gcattgtgtg atgctaaaag atgtgttcca
     7261 gcagctgcat ggcagctgct gtaacaagct cgttaaacga gcttgttaca gcaaatatga
     7321 tgtgaatttt ccggaagggt tgtcatatgg agaagatact tatgtcagtg tatgcctgtt
     7381 ggcacatcct ataaagatgg catatgtacc aaaagcattt tatcattatg tccaaaatgt
     7441 aaattacagc tcgttaacac gtcgtcctgt gaaaattttg gtagagcaat gtgaaaaact
     7501 ctgcgattta cttcgttgca aattatcaga gaatcaattt aaagaaattt atcctgcttt
     7561 acgatatagg caagcatgtg ttatcctaac atctgcagga gaaaacccat acatcgtaac
     7621 atttaaaaaa gattttgaag gtgtgagaaa agctattctt catcaaaact tctcttttaa
     7681 gaggaagact cttttttgga tagcattcta tatatcacct tatattgcac atttttttta
     7741 tactttttgt cgttaactat tgttgaatct tatcataaac agttagcaat tttattagtt
     7801 ttatgtctga tgtctcaaga atagatacat atggtgcaaa gctggtttta ctgccatata
     7861 tgttggcaat aattggcagt tgtttgtata ccattatatt gggagtgtat aacggggatt
     7921 tcatacaacg tgatgtgtta tttccgttac ctgctttgtt ggttatagct gtattgacta
     7981 tcattcctta tataggtata tatggattgt ataaacggta taggtctaaa gagacagaaa
     8041 atgtacccga taagttcaag gttgcgataa ttcgcaatat tacatggctt ttattgttgg
     8101 ttcatatagg tctactcttt actggatatg gccaaatggg aacttcgata gaaatagacg
     8161 gcggattttt ttcttatatc cgttcggctt tcttcaagtt gatggtacgt ccatgggtta
     8221 ttgcttattt gctgatttcc aatagccgta aaaatcttgc tgtaactgtt cttttgtttt
     8281 ctattcacac gattcttgct cattctttag gagggttctt tattctatta ctcatcttat
     8341 tgtttaggca aggcaagaag gtgaaatctt ttgtgaagcg aaatttcttg tttgtattag
     8401 cgatactcta tttggttccg attgttgtct cttccgctta taatgttcgt gcacaattaa
     8461 ggggacaagg agggatgagt gaaacttcaa acatggatat aatggttggg aaattatgtg
     8521 gacgaataag tagtttttcc aacagtgcct atattttaca gaactcgtca caaaatgttt
     8581 atgatttgga attaatcccc gatttttttt acttttatga tacattacat tattggggat
     8641 acagacctga gtttaagagt actggattct atgtggaaga gcaaataaag cattcaaaat
     8701 tagaaaacag ttcaactatg cctggtgtca taggggtttt aataatgtca tatgttaaat
     8761 ctccttacat atttcttttt aacctgtttc tgatgacttt tcttcttatt ataatattta
     8821 atctaacaaa gaggatagga tttccaaatg cttctggaat tgcttatatt ttaacaatag
     8881 agtttgctac aagtggagat atttcagctc tttctaatac tatatatacc ctgctgataa
     8941 tatggtttac attgtctata tcaaacataa taatatggaa atgaaaaaga aaaagaaagt
     9001 acttgtgtta tatccatcgg ggaattatct atatcctacg acaggaggag agttatatga
     9061 ttcttatctt tttaaaagaa tacttttttc aggacagata gatatgtcct tttttacaaa
     9121 ggatcatact agacgcatta ataagtggtt gttgcctgca tacatactct ggtcgtgtag
     9181 gagaatcggt tcatacgatg ctgtattctt aaatagcggt tggtttgctc aatctatttg
     9241 gctgctttat tttttcagaa tattttatcc taagttgaaa gtctatgtta ttcatcatca
     9301 ttttcggtac caagaaatgt ctggaataaa aagacaatta cagtacatgt tggaatggct
     9361 gggattgggt gtgtctttcg ctattataac tcccaatcca tatacgcatt ccttgataaa
     9421 gcagatgaga ccagatagtc gtactgtttt tctcgaaatg gcattcaaga aagatgttcc
     9481 aacatgttct tgctatgtgt tgaaacagtt attatttgta ggtactgtat atcaacggaa
     9541 aggactttta tatttactgg aggcaatagg acagatgtct gaaaaggaaa gatctggtat
     9601 tcatttggat attgtggggg atctttctca aaaaaaatac tataaatgtc tgttgtcttt
     9661 ggttcactta tatgggctgg aggatattgt aacttttgta gggcgtatat cagatgaaga
     9721 attgaggtca tattattctc gagcatattg ttttgtattt ccatctttac tggaaggtta
     9781 tggtatggta ttaattgagg ctatgtctta cggactaccg gttatagcgt ttgataattc
     9841 agctatacct tttacagtaa aaaatgatag gaatggcata ttagtgagga ataaaagcat
     9901 attggatcta aaaaaagcca ttttgaaact gtgtgtagat acagattacc atcggaaatt
     9961 gtgtgatggt gctctagata cttatcgcaa tgctcgttct ctttctgatt tggatataga
    10021 tatagaaaat tttgtaataa aggaactaat aaactaaatc aatatggaag taatgttgga
    10081 gtattaaatt tattatagta taatggtgat tgtgaaatta taaggcaatt atgcatgaaa
    10141 ttttattggc gtatgttttt gagaaaaact ttaaaaattg catgagaagt cagaatttta
    10201 ttatcgataa aattatattg gatacctgct aatattaaaa ttataattga tttttaatag
    10261 aatttagttt agggcatagt aaagtgctct ttaaaaaggg tgttacttaa tttagtacta
    10321 acgtaaaagt gtctttaaaa agaggtgtta tctaaattga atattaacaa ataagtgatg
    10381 atttgaattt attagaacgg aattatgaaa atatgtttct tttgtaagat atcagataag
    10441 agtaagctat ttatagtcga attctataat caggatatta aaatcttaaa aaaaatagat
    10501 cccagtttga cgatagctac taaatatagc gaaatagatt ggagtgcaga tgtaattttt
    10561 gtttggtggt ggacatatgc cttttttcct gtatttgttt caaagctgtt gaggaaaaaa
    10621 gttgtaataa caggaacttt taattataag tgtccaatgg ttgcttcgga ttactataga
    10681 agaccgttat tagaaaggtt attgattaaa ttttctatta aatatgcaaa tgaaaatatt
    10741 ctagtctcaa gaaatgagta tgaacaaatt tataaagatt ggaatcttaa aaatatagta
    10801 tattctccac attgtataga tactgtaaag tattcaaggg gaatgtattg caatagagga
    10861 aatgaattgt ttactatttg ttggacagga aaagaaaatg tgaaacgaaa atgtttgtat
    10921 gagattatag attcggttga attattgaaa gataagttag atatgcatct taatattgca
    10981 ggacataaag gagatgcttt tgatgaagtg aagaaatata tatcagagaa aggtttaaat
    11041 gcttatatta gtattttagg tgaaatctca gagaaggaaa aattgtgtta tttgaaaagc
    11101 tgtcgtttct atttacaacc ttcacgatat gaagggtttg ggttagctat tgcggaagct
    11161 atgagttgtg ggactgtagt cgtaacaaca gatgttggag aagttctaaa tgttgttgga
    11221 aatgcaggaa taataataag gaatacatta ccggaaacta ttgctaatgt tatagaggat
    11281 tattggaata atgatttaga gagtattagt attgcggctc atagtaggat tgaaacatta
    11341 ttttcaatgg caagaagaga aaaagatata atgaatgttg tgaaaaagta taaagaataa
    11401 ttatgaaaca gattattcaa gatataaaat cagggcgaac tgtgcttgaa gaagtaccag
    11461 ttcctcaagt aagagcaggt tatgttctag ttaaaacgtc tcgttcttta gtatccttgg
    11521 gaacggagcg tatgctcgtg gagttcggaa aggcgaacct gattgataag gcacggcaac
    11581 aaccggataa ggtggagcaa gttttggaca agataaagac ggatggtttg caaccgacac
    11641 tggaggccgt gttcaataag ctagggcaac ctttgccttt gggatattgc aatgtcggac
    11701 gtgtggtagc tgtagggaaa ggtgtcgcgg agttcaaggt ggacgatcgg gtggcctcga
    11761 acgggaacca tgcggagttt gtttgcgtgc cgaagaactt ggtagcgaag gtgccggatg
    11821 atataacgga tgaggaagcg gccttcacgg tgattggctc gattggcttg caaggaatcc
    11881 gcttattgaa tcctcagttg ggagagacgg tcgtggtggt cggtctggga ttgatcggtc
    11941 tggtggcggc gcagttgttg agagcgaacg gctgtaaggt tatcggggtg gattttgacc
    12001 agcagaaggt ggatatggcc gcctcgaagg gaatcgtggc cgttaatccg ggcaaaggta
    12061 cggatccggt aaggttcgtg gaggattata cgggtggtat cggtgcggat ggtgtcttga
    12121 tcacggcctc cacgcaaagc catgaggtga tccatcaagc gtgtgagatg tcccgtaagc
    12181 ggggacggat cgtgttggtg ggtgttatcg gattgaatat gcgaagggat gacttctata
    12241 agaaggagtt gagttttcag gtatcttgct cgtacggggc cggacgttat gacgaggaat
    12301 atgagaacaa ggggcatgat tatccgttgg cttatgtccg ctggacggaa aagcgtaatt
    12361 ttgagacgat actccacgcg atctcttccg gatcgttgga tgtcaagtcg ttgataacgg
    12421 aagaggttga cttggtggat tatgaggaga tttacggcga tatgcgcaag aaaggatcga
    12481 tcgcctctat attgcggttt cccgctgatt caaaaatgga gtctgttgtc tctatcggca
    12541 ataatacctt tgtgagtgga aagggcaaga tcgggattat tggggcgggc aattatacct
    12601 ccgccatggt cataccttgc ttggctaagg cccacgctag aatcaagtat atagcgagtg
    12661 cccaaggatt gtccgccaag atattggcga ggaaggcggg ggcggagaac gccacgtcgg
    12721 actatcaaaa tatattgaaa gatccggagg tggatttggt gatggtcacg acacgccata
    12781 acctgcatgc ccggatggtg atagaggctt tacggaatgg gaaaagcgtg ttcgtggaga
    12841 aaccgttatg cttgaatgag acggaattgg atgatattat acgggcttat caaggggctc
    12901 ctgagggcac gaccttgacg gttggtttta accggcgttt ctctccgttc gccgagaaaa
    12961 tgaagcgatt gctaggtgac ggacctaaaa atatagtggc gacgatgaac gccggattta
    13021 tcccgcaaga agtgtgggta cacgatctag agataggtgg agggcggatc attggtgagg
    13081 cttgccattt tatcgatcta tgttccttct tggcgggctc ggaggtcgtg gcggtctgca
    13141 tgaatgcgtt aggcgaaaat ccggaggaga atacggataa tgccagcata ttgcttcgtt
    13201 acgcaaatgg gacgaacgcc gtgatcaatt actttgcgaa cggctcgaaa tcgtacgcga
    13261 aggaacgtgt ggaggttttc tctcaggaga gggtcttggt cttggataac tggcgtaaat
    13321 tgaccgggta tggttttaag ggtttctctt cgatgaaggc cggtatggat aaagggcaaa
    13381 aacgtcaatt tacgttgttg aatgaacgta tccgggaggg cggtaagcct ttgattccat
    13441 ttgggagtat attgaatacg acgaaagcta ctttcgcttg cattacgagc ttgaaagaga
    13501 gatgttgggt gaatctctaa aattatatat ttctactctt cggaacttga gatctcgcca
    13561 agttcgttat caagtctggt ataggctacg ggcatatatt aggaaataca ggagctttcg
    13621 gtatgtattg tcattaccga gagtgggaca tcctttgtct tttaaacttt tcatctcgaa
    13681 atatacggac ttggatagtg ttacggggca tttctctttc ttgggtaagg aatccgcttt
    13741 tctaggatgg aacgatgaga gctttggtaa gttatggtcc tataatctaa attatatgga
    13801 ctaccttcat caagaaacta tatctttcga acaggccgtt tgctggatcg ataagtttgt
    13861 cgatgaaata gaggggaata ggaatggtct ggaaccttat ccgatcgctt tacgaggcat
    13921 caattggatc aagttcctgt cgaaatatca tccttatatt ccggcagaga ataagcgaga
    13981 atgggactcc tccttgtatg cccaatataa gattttactg gataatctgg aatatcatct
    14041 tttagggaat cacttattgg aagacgcttt ctccttgtta tgggccgggc tttattttaa
    14101 ggatgagtcg atctatcaaa aggcgaaaga cctattattt aaagagctgg aagaacaact
    14161 ccttccggat ggtgctcatt acgagcaatc accgatgtat cattgtatat tgttggatcg
    14221 gttgctggat tgctataatg tctctatgaa taatttgcgg tttatagggc aggaaggtct
    14281 gaatgaacgc ttacgggaga aggctagtag catgttggga catttagcct ctgtcgttta
    14341 taaagataat acgatacctc tcctgaatga ttccgctgag ggaatcgcgc cttctccgac
    14401 tcaattgttt gcatacgcta agcgattgga tatggattgg gaaaagcttc cgatggaagc
    14461 gtgtggctat cgaaaattga tggcgggcca ttgggaggct atcgtggatg ttggagacat
    14521 aagggcctct taccaacccg gccattcgca tgcggatatg ttcaattatg agttgcggat
    14581 agggggtaag cttttcgtta tagataccgg aatttctacg tatgaaaaga cagcccgtag
    14641 gcaatacgag cgtggcacgg cagcccataa tacggtgatg ataggggata agaactctag
    14701 cgaggtatgg ggaggctttc gtgtggggag gcgggcaagg gtgacgcttc ttaaagattc
    14761 tccgaatgag gtggaggctt ggcatgatgg ctttggctca ttgggtaggc atcggcgaaa
    14821 atttacgatt gataaggatt gttttaggat agaggactct gtctcaactg gcgtgaaagc
    14881 cgtaagcttg atccatctgg ctccggatgt ggagatcatg tcttgttcac ggactgagat
    14941 cgtgacgaat atcgcagcga taagagtggc cggcgcatcc tctgtcgaga ttgtagatga
    15001 ccaagtgtca tttacgtata accgttttca cctatctaag acaattcgta ttcattttgt
    15061 gaagagactt tcttatacaa tcggttgatc gttgttggac cattcttgat ctgcctaata
    15121 tcttacttaa aaaataatac ataattctta tgaaagcatg tttcatgggt ttgggctata
    15181 ttggcctgcc cacggctatt attgccgcaa agcacggggt ggatatcgcc ggcgtggata
    15241 tcaacgccca agtggtggag gttaccaacc aagggaaatt gcatatcatc gagccgggta
    15301 tggaggagat gttgcgggag gtgctggcct ccggacattt caaggcttac accgagcctc
    15361 gggtgagcga cgcttatttc atggtggtac ccactccctt caagggggat catgagccgg
    15421 acgtatcgtt cgtggagtcg gctacccgta tggtgcttcc tttgttgaag gagggggatt
    15481 tgtacgtgat cgagtctacc tcgccggtgg ggacgaccga acggatggct agtttgattt
    15541 tctcggaacg gccggagctg gagggcagga tctatatcgc ttattgcccg gagcgggtgc
    15601 ttccgggtaa cgtgatccat gagttggtgc ataacgaccg ggtcatcggc ggcatggacg
    15661 aggcctctac ccgtaaggcg atggagttct acggccagtt cgtgaagggt acgcttcacc
    15721 caacgaatag caagacggcc gagatgtgta aattgaccga gaactcaagc cgggacgtgc
    15781 agatcgcttt cgccaatgag ctgtcgttta tctgcgataa agcgggaatt aatgtgtggg
    15841 agctgatcga tttggcgaac aggcatcccc gtgtgaatat cttacagccg ggttgcggtg
    15901 ttggtggtca ttgcatagcg gtggaccctt atttcatcac ggcggagttt ccgatggaga
    15961 gccgtatgat ctcgacggcc cgtgagacga ataattacaa ggctttttgg tgcgctgaga
    16021 aagtgaggaa cgccatgcta cggtttgagc tgaagcatgg gcgtaagccg gcggtggcaa
    16081 tgatgggctt ggctttcaag cctgatatcg atgacttgcg cgagtctccg gccaagggaa
    16141 taacgacgaa ggtgttgcag tcgtgcaaca acgctgacat catggtggtg gagccgaacg
    16201 tgtcggagca taagctgttt aagttgaccc cttataagga ggcctatgag aaagccgaca
    16261 tcgtggtttt cttggtgaat catagggagt ttgcggggtt gaattatcgg gatgacgtgg
    16321 aggtgctgga cttttgcggg acattcaaga aataatcgtt cgctaaatag aaacgcagta
    16381 atgaggaaaa taatgttagt cttcgggacc cgtcccgagg cgatcaagat ggctccgctg
    16441 gtgaaggagt tccaaaaaca tccggagtcg ttcgagacca tcgtgtgcgt taccggacag
    16501 catcgggaga tgttggatca agtgttaaaa ttgttcgaga tcacgccgga ttatgatttg
    16561 aatatcatga ggcagggtca ggacttatat gacgtgaccg cccgtgtcct tgtgggtatg
    16621 cgtgacgtgt tgcgtgaggc gacacccgat gtcgtgctgg tgcatgggga taccaccacg
    16681 agcacggcgg ccgccttggc cgctttctac caacagatac ctgtaggtca tatagaggcg
    16741 ggccttcgta cccacaatat ctatagcccg tggccggagg agatgaaccg gcagattacg
    16801 gggcgtatcg ccacgtataa tttcgcaccc acgcggttga gcaagcaaaa cttgatgcga
    16861 gaggacgtga atccggactc aatcttggtt accggcaata cggtgataga cgccttacgg
    16921 caagtggtgc gtaagataaa gacggacgct gagttggaca aggagctgga aggcgtgctt
    16981 ttacgctccg ggtatgatgt gaaccgtctg gttgagggta agagactggt gttgatcacg
    17041 ggtcatcgcc gggagaactt cggtgatgga ttcatccata tgtgtaccgc tatcaaggac
    17101 ttgacccgga agtatccgaa ggtggatttt gtctatccta tgcacttgaa tcccaatgtg
    17161 cgcaagccga ttcatgaggt attcggtgag gatctttctc atttggagaa tatgttcttc
    17221 attgagccat tggaatatct gtcgtttgtc tatctgatgg agaaatcaac gatagtgctg
    17281 accgatagcg gcggtatcca agaggaggct cccggattgg gcaagcccgt gttggtgatg
    17341 cgtgatacga ccgagcgtcc ggaggctctc gcagcaggta cggtgaaact ggtcggtacg
    17401 gactatgaca agatcgtgag cgaggtctcg gcgttgcttg atgatacggc ttattacgat
    17461 gcgatgagca aggcggtcaa tccctatggc gatggattgg cttgcggaag gatcgtggaa
    17521 tttttgaacc ggaaggaatg agggtcttga tcgtttctcc ctcttatctt ccagagatcg
    17581 gtgcggcacc ctcacgcatt acaaacatgg cggagggact gtctggctta gggataaagg
    17641 tggatgtgtt gacttgctta cccaattatc ccaagggacg tatctttgat ggatataggg
    17701 gggctttttc caagacagag gatgtaaacg ggataacggt cttcaggtac tggacgtatg
    17761 cctcgatctc gaggagaccg ttggtccgtc ttgccagtat gtgcgctttc gccacgaccc
    17821 tttggtgttt cgctctcaag cgtaagcgta taaaatctta tgataaggtg atcatccaga
    17881 cccctcctgt tttggcggcg gcctcggcca tgttgctttt tcgttgttgc taccggaaaa
    17941 aggtggtact gaacgtctca gacctttggc cattgtcggc cgtggagctg ggggccatga
    18001 aagagggggg cgtttatcat ggggtgatgg ggccgtatcg agcgtttcct ttatcgtaag
    18061 gccacggcct gtcaagggca gagtaaggag atcgtggatt atataaaacg gtatgagccg
    18121 ggcaaggcct cgttcttgta tcggaatttg cagcatcgtt ttgttttacc gaatcaaccc
    18181 ccttcttctc gaaagccttt caggatcgtc tatgccggtt tgctgggcgt ggcgcagaat
    18241 atattggagt tgatagagcg tatcgatttt aaagggatgg gagcggagct tcatttattt
    18301 ggagggggca atcaagcctt ggagatagag gattatgtga ggacacatga taaaggggtc
    18361 ttttatcatg gctctctgcc caaggaacgg atgcgtgagg agcttacacg ttaccatgcc
    18421 tccattatcc ccttgacggt tcgtataagg ggggcggtac cttctaaatt atttgatttg
    18481 ctgtcgttag gcgttcctat cttgttttgt ggaggcggcg agggcgagga gattgtaaag
    18541 gagaatcagt tgggccttgt ctcggccccc ggagattatg agcgactttc taaaaatata
    18601 cgggccatga gccacttgcc ggatgaggag tatcgacagc taaaagcgaa ctgcttaaga
    18661 ttatcccaga caactttctg ttttgaaagg caactggagg cgtacaaacg ttttttatcg
    18721 gctttctaat ttcaggatga aatcccttaa acattttgcg gggatgccct gttatagata
    18781 tagtagtgtg tttttcatgg tattagattt ttagattagt aattaggttg ttcattcagt
    18841 tcgggagaat aggatgttgg tttctaaata tgagagccgg aaaggtgaga atgatttctc
    18901 tcgtttccgg ctattctttt ttatttaaaa ctcgtcattg gcgtaaagac tcaataggtt
    18961 tttcagctca taatcgaata tctcgtcatc cttgaagaag cgtttcaatt cgatctcggc
    19021 tgtctccggt gagtctgatg cgtgtacgat attctcttgt acgctcatac tataatctcc
    19081 ccgtatcgta ccgggagcgg cgtttctacc attggtagcg ccggccaagg ttcttactac
    19141 atgtatggca tctacccctt cccagcaaca tacaattacc gggcatacac tcattgcgtc
    19201 cttgatccgt tggaagaaag gcttttcttt taggtgggcg taatgctcac tcaagatctc
    19261 gtcagtcagc caaaccatct tcatgccggc cagacggagt cccttctttt cgaaacgggt
    19321 tacgatttca ccgatcagcc ctcgctgaac ggtacaaggc tttaaaataa ccaatgtttt
    19381 ttccataaga tttatattaa aagattaaac aaatgtttga tgtcttgaat acatgttaac
    19441 cttgcggcgt tttatgaatg atagaggaat aaaggatgaa atgtttttta ggatatttca
    19501 agtatatttc tatcttattc ctccgcaagt taatgggaat aaacaaataa acgagcgata
    19561 agtctgctaa actaaactaa tttaacatac gttaattgtt gctcgagttg ttaatccttc
    19621 tgtattcttt tccatttccg tggaatttcc ggatgagtct tgagaaattc cctcaaggtt
    19681 tgccggttta ctcccagttt cttgctgata tatactttag tcttatgttc tttaatatac
    19741 tgcaagatca tctcttcctt accttttagc ttacaggttt ccggtcgctc tcctttcgga
    19801 cggcccagtt tggcaccttg cacttttttc cgagccaacg cttctttcgt tcgttgcgaa
    19861 atcaggttgc gttcaatttc ggcgcttagg ctaaatgcga atgccaagat tttactgtta
    19921 atgttatttc cgagttcgta accttccttt accgtaaata caatgatgtc tctttccata
    19981 cattgatgaa ggaagctcat aacttgcata agattacgtc cgagacgtga cagttccgtc
    20041 gtgatcagga tgtcgccttt acgtatttgc tttaataatt taccaagttg gcgatcggcg
    20101 attacttttg tcccgctgat cgtctcatct acccacctgt cgattctcat gttcctcgat
    20161 tttgtgaatt tctcaatctc gaatcgctgg ttttcagtag tttgtttgtc tgtactgact
    20221 cttacataac cgtataccat atgtcctata tttaattaaa caacaaccaa gatactggaa
    20281 acggattgat tgatagtgcg ttttagtaaa aacaaacttt tttatgggtg tgttaaagaa
    20341 gttgagtggg cttgaactcc atacaaattg taataaaaag ggttaatgga tatccgtata
    20401 gaaaatttaa gttacttttg ctttcgaaaa ataagatgga gtcttagaat gatcatgggt
    20461 atgaaaaagt tattgtcttt acctccaaat ttggtagatt gtttccatgc ggtagagcat
    20521 gtaagtacag aggaatggtt ttgcacctcg gatccggtag gcgcccgctt agggtccggg
    20581 ggaggaacaa cttggttgtt ggaggcctcc cggcaaaaag aggctccgga tgtaccgacg
    20641 gaagagtggt tgggacagga gaagcgtatc ttgttgcatg ccggagggca aagccgccgt
    20701 ttgcccggat atgcgccatc cgggaaaata ttgactccga tccctgtgtt tcgctgggca
    20761 agagggcaga ggttatccca gaacttattg tccttgcaat tacctcttta tgaacggatc
    20821 atgaaaaagg caccggaatc gcttcatacc ttgatcgcta gcggtgacgt atatatccgt
    20881 gctaaccagc ctttgcagga gattcctgag gtagatgtgg tttgttacgg tttatgggtc
    20941 gagccttcgt tggccaagaa tcacggggtt tttgtatcga gccgtaagtc tccggacact
    21001 ctggacttca tgctacagaa gccttcgttg gaaactttgg gggaattggc gggtagtcat
    21061 ttattcttga tggatatcgg tatctggctg ctaagcgaca aggcggtgcg gttattaatg
    21121 aaacattcct ataccgagga tggcaaggcg atgaaggcgt atgatttata tgctgagttc
    21181 gggttggcct tggggaagaa tccacgtatc acggactcgg agttgaatca gctttcagta
    21241 gcgattctgc cgcttccggg tggagagttc tatcattatg gaactagccg tgagttgatt
    21301 tcctctacat tggcggtaca gaacttagtt agggatcaac gtgcgatcat gcagcgtaag
    21361 gtgaaaccac atcccgccat gtttgtgcag aatgcggtgt tacaccagaa attgaccgct
    21421 gagaattcgg aattatggat agagaatagt tatatcggtg agaattggac gttacgtggc
    21481 cagcaaatta taacgggtgt tccggagaat aattggaact tatctcttcc ggaaggtgtc
    21541 tgtgtagatg ttgtcccggt aggggaagct aattgggcgg caaggcccta tggttttaat
    21601 gacttgttta aaggggcctt gtctgatgtg tctaccttgt ttatggggaa acctattttg
    21661 acttgggcga tggagcgagg gatcaccttg ggagggaatg aggatataca aaacgcacct
    21721 ttgttcccta tttgccaaac cgtggatgag ctgggaaaag tgctgcgctg gatgattacg
    21781 gagccggata gagaagaggg aaagtttatt tggctttccg cccgaaaatt atcggcgaat
    21841 gatttgtccg atcaagcgaa tttacgccgt ttggtagctc agcgagaagt tttccgtaaa
    21901 aaagactggt cattattggc cgctaatcat gagaaaagtg tattctatca attggatctt
    21961 tcggatgcgg cggaaagctt cgccaaagac aagattgtct taccgaaagc ccttcccgag
    22021 gataatccgt tgatgaaaag gatacataat catatgttcc gttctcaggt gatgaagatc
    22081 tcgggggtag cgtataagga ggaggagcaa aaggctttcg ctttgttgcg ggaagggctg
    22141 gtcggttctg tcctcggaag taagcagcag ccgtgtttga atgtctatcg ggaccagatc
    22201 gtatggggac gtagtccggt acgtatcgat ttggcaggtg ggtggacaga tacgccgcct
    22261 tattgcttat atgcgggtgg aaacgtggtg aacgtggcga tcgagttaaa cgggcaacca
    22321 ccgctacaag tctatatcaa gccttccgat acccataaga ttatccttcg ctcgatcgat
    22381 ctgggagcga tggaggttat ctcctcatgg gatgagcttc gtgattataa taaggtaggg
    22441 tcgccgtttt ccattccgaa agcggctttg gccttggcgg gatttattcc ggaattctcg
    22501 gcggaggctt atgcttcttt ggatgtccag ttggaagctt ttggtagcgg gctggagatt
    22561 accttgttgg cggcgatacc ggcgggttcc ggtttaggca ctagctcgat cctcgcggct
    22621 actgtgttgg gcgctatctc tgatttttgt ggcttggctt gggataagaa tgagatcgga
    22681 aaccgcacct tgattttaga acaattgctg actaccggcg ggggatggca agatcaatac
    22741 ggtggcgtat tgcacggttt gaaactcttg caaacgaacg agggttttaa tcagaatcct
    22801 ttggtacgtt ggctgccgga atacttgttt actgatccgg aataccggcc ttgtcatctt
    22861 ctttattata cgggaattac tcgtacggcg aaagatattt tgtcggaaat cgtacgaggt
    22921 atgttcttga atagcgaggc gcatttaggt cttttgtccg agatgaaagc tcatgcgctt
    22981 gatatgtacg aggcgatcca atgcggagac ttcgtgactt atggtaaatt ggtcggaaag
    23041 acttgggagc aaaataaggc actcgattcc ggaacgaatc cggtggcggt ggaagctatt
    23101 atctccaaga tacaggctta tgccttggga tataaacttc cgggagcagg cggtggtggt
    23161 tacttatata tcgtagcgaa agacccgggt gcggccctgc aaatccgaaa gatattgact
    23221 ctttctccac ccaattcgaa cgcccggttc gtggagatga gcttgtcgaa taaggggctt
    23281 cagattagtc gttcgtaggt tcgtgccacg ccggtatagg cgagggcaca cgccagtata
    23341 ggtgttggct tacgctggta tagatacagg cctatgccta tattgttgag gggcgttgcg
    23401 tatatacgtg tgtatttttg cctgttttgt tgctaattgg aatatattgc atgtgttttg
    23461 gaacatttat ataaatgatc ctgttgtact tttgcggagt ttaatgaggt gtcagatctg
    23521 atggggaaga gaattgtttt tatatggctt ttattggcgt tcgcttgggt agcgaagagc
    23581 cagaactaca tgataaaagg aatcgtgact gattctatta cgggagaacc tttgccttat
    23641 gtggctgtga ttttgaaggg aactacgata ggtgctacga cagatctgga tggggctttt
    23701 acgctctcct cttcatctaa ggtacgtact ttacaggtct cttatctggg ttatacggag
    23761 aaagaattga aattcgttcc gggtaaagcg gaacatttga agattcagtt agctccgaca
    23821 agtattaatt tgtcggaggt gattatcaag ccgggaaagg aaagatatcg gaagaaggat
    23881 aatcctgcgg ttacctttat caaaaacgct atcgcacgtc gggagagcaa cgatcctcat
    23941 aatcatgatt attttcggta tgatcaatac gagaagatgg tcttcgctat gaacgattac
    24001 caaccgaaac cgaaaaagga tggaaaggcg ggaaagtttg acttcttgac tgagtttatc
    24061 gatacgttgg aggtgggaaa gacgatcttg ccggtatctg aacgtgagaa aatccagacc
    24121 gtttattacc gtaaagaccc gaagacggaa aagagggtcg ttctggctac gaaagcggct
    24181 ggtgtggatg aggtcttctc acgagacggt atgcaacagt tcttgaatga ggtattccgg
    24241 gaagtgaata tcttccagaa tgatattcct ttgttcttga accgttttgt tagcccgatg
    24301 tctacgatgg ggcctaactt ctataaatac tatttgctag acacggtgga ggtcgccgga
    24361 cagaagtgcg tggatttggg tttcgctccg tttactccgg agacgttcgg ttttacggga
    24421 catcttttta tcacgttgga ttctacttat ttcgtgcaga aggttaagtt gaatgtcccg
    24481 aagaagatca acttgaattt tgtcggtgga atgacgatcg agcagacttt cgaccgtgcc
    24541 ccggatggga ctcgtatcat tacgaaagat gatatcaacg tggacttcaa attgacggag
    24601 aaatcgaaag gaatgtatgc ccgccgtttg aatatctatt cgaatcaagc gtttgaggga
    24661 cccgatgatc ctaaagtatt cgaggagagc gcacctatta ttataccgat ggaagcttat
    24721 cgccgttcgg cggatttctg ggaggagaat cgtcctactg aggcgggaac tcgcaagcag
    24781 aataacgtgg agttgctaat ggcgaaactt cgttccgttc ctattttcta tgtgacggag
    24841 aaggttgttt cgatccttac ctccggttat atcgcgacga ataagattcc ggagaagagc
    24901 aagttcgagt ttggtccgat gaacacctat atcagtggta acgcgattga gggggcccgc
    24961 ttccgtgtcg gtggaaccac gacaacggcg ttcagtaaac gtcttttctt ggatggttat
    25021 ttggcttatg gatcgaaaga ccgcaagttg aaatatgatg gtatcgtaga atattctttt
    25081 atcgataaga aggattatcg gaaagaattt cccgtgcatt ctattcggtt cgagtaccta
    25141 tatgatatta accagttagg tcagcagtat atgtatacca acaaggataa tatgttcttg
    25201 gccttgaagc ggcagaaaga tacgcgtgcc acctatttaa ggaatatgga actgacgtat
    25261 taccgtgagc attataacgg ctgggcttat ggggcggtac ttcggaattt taaggaatac
    25321 tcaaccggtt acgctgcgtt tgaccgtatc ggtccggatg gccagatcac ggctaccgat
    25381 tcctaccgga tgtcggaagt ggagtttaag ttccgtttcg ccccgaatga gaaattctat
    25441 cagactcgta attaccgtta tccgattacg cttgacgcac cggtattcac cttgaaccat
    25501 acgatggctt tccaagatgt attaggtagt tcgtatgatt atcagaagac ggagctcggt
    25561 attcagaaac gcttctggtt ctctgctttc ggttatgtgg atattctcgc taaagcaggt
    25621 aaagtttgga caaaggctcc ttatcctttg ttgatcttgc cgaacgcaaa cttgtcgtat
    25681 ttggtgcaac cggaatctta tacgaatatg aacgcgatgg agttcatcaa cgatgagtac
    25741 gcttcgtggg atattactta tttcatgaac ggagccttat tgaaccgtat tccgcttatc
    25801 aagaagttaa aatggagaga ggtcttttct ttccggggta tgttcggtca cttgacggat
    25861 aagaataatc cgtatatcgg tgagcaaaat gagggcttgt tcttattccc gcagggctct
    25921 tacctgatgg acccgtctac tccttatatg gaggcgggtg tcggtatcga gaatatcttt
    25981 aagttcttgc gtttggatta tgtatggcgt ctgacctata aggatcatcc gggcatccag
    26041 acaaagggta tacgttttat gatgaagcta tccttctagg gcaagtgtta tttctagtcg
    26101 ctgaactcaa aacttaattg ttcccaacgg tctttcgtat gaggctcctc ttttacggga
    26161 ttggatacgg ataggccgat cagtcggatg ggatgctcgg tatattccac ttctttcagt
    26221 aattccttgg ccaagggaag gatcttatct aaggttgtta actcttccgg acggctgagg
    26281 cttctcgtga tttggttgaa atcgtggaac ttgaccttta aggtcagtgt gtttcccttg
    26341 aatccggaac gttccagcct gccgataagt tcggtcgcta cgtgataaag ctcgatgata
    26401 acagaggatt tgcgggagat atctttttct agcgtatgct cgcaacctac cgacttccgg
    26461 attcgtaccg cttctacggg acggttgtct atacctctgg caaactcata ataaagcatt
    26521 cccgcctttc cgaactggcg ggtaagcatc tcccccgaac attcccgtaa ttgcagcccg
    26581 ttgtggatac cgagtgtatg catttttcgg gctgttacgg ggcctactcc ccaaaaggac
    26641 tcaatgggaa gacgtgctat aaaatcgagg gcttggcttg gatggatggt gcataatcca
    26701 ttgggcttcc gataatccga ggctattttc gctagaaatt tgttgtagga gactcccgct
    26761 gacgctatca ggttcaaatt atcccagatc cgtttcttga tctccttggc gatatctaca
    26821 gcgagagaga tgcctcgttt attatcagtg acatccaaaa aggcttcatc caaggaaagc
    26881 ggttctatga tatccgtata atcatggaag atctcgtgga tctggcgtga gacggattta
    26941 tatacgtcca tccttccgtg tacgaatatc aggttcgggc ataaacgttt ggctttttga
    27001 gacgccatgg cggaacgtac cccatatttc cgggcttcgt agctagcggc agctactacg
    27061 cctcgctgct ccgcatgccc gaccgctagg ggttttcctc gcaactccgg attgtctcgt
    27121 tgttccaccg aggcataaaa ggcatccata tcgatatgta tgatct
//
LOCUS       DBMDTB010000051        27150 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_641_length_27150_cov_11.802765, whole genome shotgun sequence.
ACCESSION   DBMDTB010000051 DBMDTB010000000
VERSION     DBMDTB010000051.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 27150)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 27150)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27150
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_641_length_27150_cov_11.802765"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(7..93)
                     /locus_tag="ACZPB4_09540"
     tRNA            complement(7..93)
                     /locus_tag="ACZPB4_09540"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(57..59),aa:Ser,seq:cga)
     gene            complement(232..783)
                     /locus_tag="ACZPB4_09545"
     CDS             complement(232..783)
                     /locus_tag="ACZPB4_09545"
                     /EC_number="1.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH peroxidase"
                     /protein_id="HIR1098494.1"
                     /translation="MKKKWICTVCGYVHEGDEAPEFCPQCKQPKSKFKELVETEGALQ
                     FVDEHVLGVAKGVDPVILEGLNAHFMGECTEVGMYLAMSRQADREGYPEVAEAFKRYA
                     WEEAEHAAKFAELLGDVVWDTKTNLKKRMEAEAGACEDKKRIATLAKQQNLDAIHDTV
                     HEMCKDEARHGKGFEGLYNRYFK"
     gene            939..1997
                     /locus_tag="ACZPB4_09550"
     CDS             939..1997
                     /locus_tag="ACZPB4_09550"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005640235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I fructose-bisphosphate aldolase"
                     /protein_id="HIR1098495.1"
                     /translation="MDTSKIISLLGDKSDYYLNHVCKTIDKSLLHLPSPTCVDDVWGN
                     SDRNIQTLNSLQTLLGHGRLANTGYVSILPVDQDIEHTAGSSFAPNPIYFDPENIVKL
                     AIEGGCNAVASTFGILGSVARKYAHKIPFLVKLNHNELLTYPNSYNQIVFGTVKEAWN
                     MGAVAVGATIYFGSEQSRRQLVEIADAFEYAHELGMATVLWCYLRNSSFKKDGIDYSA
                     AADLTGQANHLGVTIKADIIKQKLPENNGGFTAINFGKIDQKMYTELTTEHPIDLCRY
                     QVANNYMGRVGLINSGGESHGASDLKDAVVTAVINKRAGGMGLISGRKAFQRPMKDGV
                     ELLHSIQDIYLDKDITIA"
     gene            complement(2066..4177)
                     /gene="dpp5"
                     /locus_tag="ACZPB4_09555"
     CDS             complement(2066..4177)
                     /gene="dpp5"
                     /locus_tag="ACZPB4_09555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_function: GO:0008239 - dipeptidyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0043171 - peptide catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidyl-peptidase Dpp5"
                     /protein_id="HIR1098496.1"
                     /translation="MNKSIGTMIMATSLLLGACNPATDVNVKETGDKNLIGKSDIRIK
                     DGRMTPEALWAMGRIGGMNVSPDGKRVVYTVAYYSVPENKSNREVFVMNADGSDNKQI
                     TKTGFAENEAVWIKGGTKIAFLCNESGSSQLWEMNPDGTDRKRLSDYDKDIEGFAFSP
                     DEKKVLFISQVKTVNSTADKYPDLDKATGVIITDLMYKHWDEWVTTVPHPFVADFDGE
                     SISNPVDVMEGELFESPMKPFGGIEQLAWNTTSDKIAYTSRKKTGKEYAISTNSDIYV
                     YDLNTKQTTNITEENKGYDTNPTYSPDGKSIAWLSMERDGYEADQNRLMVMNLETGEK
                     TFVSKDFDSNVDSYCWSADCERIYFTGVWHGESQVYQIDLANGNKITPLTEGMYDYAS
                     VALLGDKLIAQRHSMSMGDEIYSIDLTGDHTVTQLTFENKHIYDQLTMGKVEERWMKT
                     TDGKQMLTWVIYPPQFDPNKKYPTLLFCEGGPQSPVSQFWSYRWNFQIMAANDYIIVA
                     PNRRGLPGFGLEWNEAVSGDYGGQCMKDYFTAIDEVAKEPYVNKDRLGCVGASFGGFS
                     VYWLAGHHDKRFKAFIAHDGIFNMEMQYLETEEMWFANWDMGGAYWEKQNATAQRTFA
                     NSPHKFVDKWDTPILCIHGEKDYRILANQGMAAFNAAVLRGVPAELLIYPDENHWVLK
                     PQNGVLWQRTFFEWLDMWLKK"
     gene            4263..4751
                     /locus_tag="ACZPB4_09560"
     CDS             4263..4751
                     /locus_tag="ACZPB4_09560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SPOR domain-containing protein"
                     /protein_id="HIR1098497.1"
                     /translation="MNKIWLFGAAVCMVLALGSCKPKQSAYKAAYEQAKEKESTAPVE
                     VVEQEEEVVEVAPVSKPRTSTATTRTEKINAAQGEDASRLKRYSVVVGSFKNKTNAYA
                     LKERMQNDGYNAVLGENEQGMLRVIVASFDNKADAADSRDAIKAKYAPNFQDAWLLER
                     AY"
     gene            complement(5044..5922)
                     /locus_tag="ACZPB4_09565"
     CDS             complement(5044..5922)
                     /locus_tag="ACZPB4_09565"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008771815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase family protein"
                     /protein_id="HIR1098498.1"
                     /translation="MEQVTESRRKPIVVGIGELLWDMLPSGKKAGGAPINFVYHASCL
                     GAEGYAISAVGDDELGKEIVDELDKNHIQHLIEKVPYPTGTVQVELREGIPTYTIHER
                     VAWDHISPTSDAIDLAEKADAICFGTLAQRSRQSRETIQAISSFAPKDAYRLLDINLR
                     QRYYDKELIEESLYLANVLKVNDEEFNVLRDLFGLNGTEREVALWFIEKYGLRMFVLT
                     AGSSHSTIYTREEISTLPTPEVTVADTVGAGDAFSGALIISLLKGKSLSEAHHFAVKT
                     AAFVCTKEGAWPVYEE"
     gene            complement(6098..8833)
                     /locus_tag="ACZPB4_09570"
     CDS             complement(6098..8833)
                     /locus_tag="ACZPB4_09570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HIR1098499.1"
                     /translation="MKGNPLYILLWLFLILCFACSPGKKEKKYVIGVSQCSMTDIWRQ
                     SMIRDMEVEALNHPEIELVVMDASQDNDTQISQIKGFIKKKVDLLIISSNETEPVTPV
                     AVEAYRAGIPTIILDRKINSDEYTTYIGADNYEIGRSIGMYISSLIKGETTILEIWGR
                     RGSSSATERHQGFVDAMSIDPNVKIRELDGYWYKENAYEEVLKLDSIEDVDIVFAHND
                     MMALGAREAIEERDSSLVGHVEFIGVDGLLGGGLGVEAVAQGKLDASFYYPTGGGVAI
                     KVAWQILSGQAYTKKYALSTAMIDKTNAGTLYLQSDRLVEYQRQIEKQRANLSQLLSK
                     YNFLYSSLIIILILALLLGGSAIYTVYINRKVRQKNHLLNEKNRLVQQQKEELSVANQ
                     RIEQVTAQKLQFFTNVSHEIKTPLTLILGSLSKMAQDAPAGAFADDIRIVKKNAERLK
                     RVIDQLLDFRKIENNKMGLRVTKMDLVFFIQEVKSYFDTLAQSKRIDYTFLHEMDSLF
                     VWVDTDKMEKILTNLLSNAFKFTPEQGKITIRLREEETEVVLSVEDNGEGIPPENLAS
                     VFERFFTSGQSYAPGTGIGLHLTREFVLMHKGSIHVESEQGERTVFTVQIPKGKSHFD
                     ESCVFLSNATESSSGVAHLDISQVQETLNKKYDYMILIVEDDWDIRAYLQHELSGNFN
                     VLVAENGAKALDILLKENVSLVVSDVMMPEMNGFELCRRVKSDMALSHIPVILLTALS
                     DDSQRLYGFEGGADEYIQKPFNIEIVKLRIIKLLEERNRLREVFLKESQSPAGLSIET
                     KGKVESLDDLFMRKFIALIEENYSDPDFSIEKGSEKLGLSRVHLYRKVKELSGITPTD
                     FLRNYRLKKASALLKQRSGTISEVAYATGFGSPAYFSKCFKAVYNITPTEFIESL"
     gene            complement(8878..9786)
                     /locus_tag="ACZPB4_09575"
     CDS             complement(8878..9786)
                     /locus_tag="ACZPB4_09575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098500.1"
                     /translation="MRRFFIAIFRYLGVVGCLGLLSCLLIRSYFHISVPSLKSDPEVE
                     VLILGDSHPLHSISADMLGKSRNDAKSSENYFNTYIDLCLKAPYLPHLKTVILGFGYH
                     TFTVADDSYQDEFPAYMSIYPHLKEREDLRLLVQEAVSPVTRKEVMYSYEFGVPFKNC
                     VAEIKRNVIERIFTGATGGTLDVIIDRHYYDDKGAYLLPSSFQQEMLGRIVEECKKRD
                     LSLILYNAPVSTEYMERVPSSYRELTDSLAREYVDDKTVFYLNYTAVPLPDSCYRDAD
                     HLNEIGIHRFTPLLKDTLTCLGVISE"
     gene            complement(9792..11249)
                     /locus_tag="ACZPB4_09580"
     CDS             complement(9792..11249)
                     /locus_tag="ACZPB4_09580"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBOAT family O-acyltransferase"
                     /protein_id="HIR1098501.1"
                     /translation="MLFNSIEFLIFLPLVFFGYWFVFKSLRWQNLFVVAVSYLFYGWW
                     DWRFLLLILFTSLCSYLSGVYLEKCAGNRSVQKWISAGNILLNLSILGVFKYFDFFTE
                     NLVNVLHLLGWDADYVTLNILLPVGISFYTFQALSYTIDVYQGKIKATHDIVAFFAYI
                     SFFPQLVAGPIERATHLLPQFLRPRNFDCDLALDGIRQMLWGFFKKVVVADNCALFVN
                     GVFENYQTLDGSTLFLGAFFFTIQIYGDFSGYSDIAIGCARLFGIDLMQNFKYPYFSR
                     DIAEFWRRWHISLTTWFRDYIYIPLGGSRAGKWKSFRNTLVIFLVSGFWHGANWTFVA
                     WGAYHALLFLPLLLLGQNRRYRDSVAENSFLPSVKELTQMGATFLLVLLGWILFRSED
                     ISQAAVYLERMFNVSLFSAPQLVGLGFGQLLLKKCFFFTALMFVVEWIGRKQAHGLMI
                     EDLSLPVRYVIYTVLLIIIYGFDASNPQGFIYFQF"
     gene            11370..11837
                     /locus_tag="ACZPB4_09585"
     CDS             11370..11837
                     /locus_tag="ACZPB4_09585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WbuC family cupin fold metalloprotein"
                     /protein_id="HIR1098502.1"
                     /translation="MKIINEQLLDETQAKALQSPRLRMNYNFHEKLDDPINRLLNAME
                     PGTYLRPHRHLNPAKDEIFLLLRGKVAVFLFDEEGNITEKTILNPKEGAYGAEIKAGT
                     WHGLLVLESGSVIYEIKQGPFAPLAPENLAPWSPEAEDTEGVKKYLEWLESQI"
     gene            complement(11991..12809)
                     /locus_tag="ACZPB4_09590"
     CDS             complement(11991..12809)
                     /locus_tag="ACZPB4_09590"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HIR1098503.1"
                     /translation="MKRQIFSLFLLLLTLVACGDKPLDPNKPVYVKIKTTMGDVTVLL
                     YDDTPLHRDNFIKLCQSNEYEGMLFHRVIKEFVVQGGDPESKAHEPGALYGDGDGGYT
                     VPAEILPNHFNKKGALIDAKEIDAVNPERASAGTQFCLVQGKVLDDKELAEKEARINE
                     IRRNWLYYKFRDELKKQDPSLAADSLENELHARASILVEDTLAVLGPVVIPAERREIY
                     KTIGGVPHLDGSVTIFGEVVEGFDIVEKISVVKTDKNDRPLHDVMIKSTKVFQK"
     gene            complement(12849..14693)
                     /locus_tag="ACZPB4_09595"
     CDS             complement(12849..14693)
                     /locus_tag="ACZPB4_09595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
                     /protein_id="HIR1098504.1"
                     /translation="MRKEPRSIELLSPAKDLICGREAINHGADAVYIGAPKFGARAAA
                     GNTLDDIRQLCDYAHLYSARIYVALNTILKEEELAEAEQMIWQLYEAGADALIVQDMG
                     ITQLNLPPIPLHASTQTDNRTLEKVRFLQEAGFTQVVLARELSLNQIREIAERTTVPL
                     EVFVHGALCVSYSGQCYLSAALSGRSANRGECAQYCRLPYSLIDADGKEIVSGKHLLS
                     LKDMNRGEYLEELLDAGVSSLKIEGRLKDVSYVKNVTAWYRKKLDAILARRPEYRRAS
                     AGHSTYTFQPVAEKSFNRGFTPFLWKERTKDITSFDTPKSLGEPVGTVKELKGNSFTI
                     AGLKQLNNGDGLTFFNEKGELEGFRVNRVEANRIFTLDRPAIRPKMPLYRNFDQEFDK
                     LLSKPSAERKLSVRMEFQDNAFGFTLSMADETGARIMLTKPFEKEPARRDQAENIRTQ
                     LSKLGNTPFEAEEVAVAMSDNWFVPSSLLAEMRRQGVERLISTRRIRYRREEARPVKP
                     CVGEATEIPFPEKRLTYLGNVSNSKAGAFYKAHGVTAVEDAFELSPRKDVPLMFTKHC
                     LRYSMGWCPTYQKQKSPYKEPYFLRYKETLLRLRFDCKNCQMLIYAEE"
     gene            complement(14694..15626)
                     /gene="metA"
                     /locus_tag="ACZPB4_09600"
     CDS             complement(14694..15626)
                     /gene="metA"
                     /locus_tag="ACZPB4_09600"
                     /EC_number="2.3.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010800193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004414 - homoserine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-acetyltransferase MetA"
                     /protein_id="HIR1098505.1"
                     /translation="MPLNLQKNLPAIELLKKEHIFVMDSLRASEQDIRPLRVVVLNLM
                     PLKITTETDLVRLLSNTPLQVELDFMKIKGHTPKNTPIEHMQEFYKDFDEMADDFYDG
                     MIVTGAPVEQMPFEEVSYWEEITQIFDWARTHVTSTLYICWAAQAGLYHFYGVPKYDL
                     PAKMFGVFRHSLREPFVPIFRGFDDEFFVPHSRHTEIRREDIMKVPELTLLSESEESG
                     VYMAMARGGREFFITGHSEYSPYTLNDEYMRDLGKGLPINKPRNYYRNNDPAQGPVVR
                     WRGHANLLFTNWLNYYVYQETPFRREDIKKLGSL"
     gene            complement(15677..16912)
                     /locus_tag="ACZPB4_09605"
     CDS             complement(15677..16912)
                     /locus_tag="ACZPB4_09605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-bladed beta-propeller"
                     /protein_id="HIR1098506.1"
                     /translation="MRQSLIAAGMFLLTGGMVGCGTSSTQEKEDLIVVDVSKDYPKKE
                     LILQDLFDVEYIPLETTDEFVTLGWLQAIGKDVMIIRNMFAADGDIFIYDRKGKAIWH
                     INRKGQGNEEYAATNGIYLDDEKGELFVGNLRQRKIMTYDLFGNFKRSFTFKEGEDED
                     TKSWVYYKAIFNFDRDHFICQDASSGRNFNGAYQDLEPRNIFLIVSKQDGSVVEEIKV
                     PFEKKVSQVLFDEKGIGMVNNPCIVPYEVRWLLTEPSCDTVYTYSSAEGLKPFIVRTP
                     SIQSMSPEIFLFPGVVTDRYCFMQTVKKELNLAMMDTYYRLMRTDLVYDRETKEVSEY
                     VLYNDDFTKEVPIANLVDEIFDLTVFNNDEIAFTWRINTPELVEAYQEGHLKGKLKEI
                     AAGMHEEDNPVIMVAKYKR"
     gene            complement(17175..18554)
                     /locus_tag="ACZPB4_09610"
     CDS             complement(17175..18554)
                     /locus_tag="ACZPB4_09610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0015288 - porin activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux transporter outer membrane subunit"
                     /protein_id="HIR1098507.1"
                     /translation="MMTKNFYIAAFVVSMLAFSSCKIGKRYVRPELNLPDRIEAYTDT
                     TDTASVENIPWESLYADEALKDLIRKALDNNKDMKIAAAKVKEMIAAKRISFASMLPE
                     VGANIYAQKERLNYGGDNPKPDPEFGAKLTLSWELDLWGNLRWANEAAIASYMETVEG
                     QRALRLTIIAEVAANYYQLCALDQELSIVQQTLDARREGVRLAKLRYEGGLTSETAYN
                     QAQVELARTETLIPSLERQIKIKESDLSMLLGEYTDDIPRGLSLSDQHLPDALPIGLP
                     SSLLERRPDMRQAEFKLRAANAQVGVAQTDLFPKIRLTSNYGFESDELSSILKSPAGF
                     IAGSLLQPIFAMGKNKAKVKAAKARYEQEVYSYEKSVLGAFKEVNNAIVTVRKVKEIR
                     ASRMNLEASASKYLELAQLQYINGVISYMDVLDAQRGLLDAQIGLNNAVLDELLSVVY
                     LYKALGGGF"
     gene            complement(18551..21715)
                     /locus_tag="ACZPB4_09615"
     CDS             complement(18551..21715)
                     /locus_tag="ACZPB4_09615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0042908 - xenobiotic transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HIR1098508.1"
                     /translation="MKPGFFIDRPVFSTVLSILIVIVGIIGLALLPVDQYPQITPPVV
                     KISATYPGASALTVSQAVATPIEQELNGTPGMIYMQSSSSNSGSLNITVTFDVSADAD
                     LAAVEIQNRVKLAESRLPAEVIQNGITIEKQAPSQLMTLSLMSDDPKFDEIYLSNFAT
                     INVLDVLRRIPGVGRVSNIGSRYYGMQIWVYPDRLANMGLTVSDLQDALKDQNRESAA
                     GELGKQPVLDVDVTLPITAPGRLSTVKEFEDIVVRANPDGSIVRMSDVARVSLEASSY
                     STESGINGKNAAILGIYMLPGANALEVATKVKEAMKDISKNFPEGLEYNFPFDMTEYI
                     SQSVHEVYKTLFEALFLVVLVVFLSLQNWRAALIPTIAVPISLIGTFGFMLIFGFSLN
                     MLTLLGLILAIGIVVDDAIVVVENVERIMAEERVTAREATHKAMRELSGALIATSMVL
                     AAVFVPVSFLGGITGQLYRQFSVTIVVSVLLSTVVALTLSPAMCAIILRPSHKKKAFI
                     FRKINLWLAKGNKKYTKLLRISIANPRRILAGFGMVLVAIFVLNRMLPTSFIPEEDQG
                     FFTVELEMPEGTTLERTRAVTDRAIEFLDHHPAVAYVQNVTGSSPRVGTNQGRATLTV
                     ILKPWEERKSSGMKVEDVMADARREFYYYPEAKSYVNRPPVIPGLGESGGLEMQLEAK
                     GDASWDNLVSATDTFLYYASQAPELQGVSSAMQSEIPQLYFDVDRDQAKFLGIPLSDI
                     FSTMKAYLGSVYVNDFNMFNRIYRVYIQAEAPYRATRDNLDLFFVRSKDGAMVPLTAL
                     GTTQYTTGPGTIKRFNMFTTASINAVAAPGYSTGEAMAAMERIAREHLPENIGLEWSG
                     LSYQEKQAGGQTGFVLALVFLFVFLFLAAQYESWIVPIAVLLSLPVATLGAYLGIWAT
                     GLENDIYYQIGLVTLIGLAAKNAILIVEFAKVQVDNGVDVVRAAIHAAQMRFRPILMT
                     SLAFVLGMLPMVLASGPGSASRHSIGTGVFFGMLVAITVGIVLVPFFFVLIYKIKGKM
                     RMERIAQKKEVVTSILKRHKNGKL"
     gene            complement(21712..22878)
                     /locus_tag="ACZPB4_09620"
     CDS             complement(21712..22878)
                     /locus_tag="ACZPB4_09620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HIR1098509.1"
                     /translation="MSKKRLAKVQVILIALVVAMTGCHHKEEQQLPIVIVDKPSKEDV
                     QIYGEYVGRIRAASFVEVHARVEGFLEKMLFEEGKRVKQNEPLFMINPDKYRARVEKA
                     KAQLKKSQAQAAKARRDVERLKPLYEQHAASQLDLDNATAALEDAEANIAMSKADLDQ
                     AEMELSYTVVTSPLSGYISERFVDVGALVGPGVNSKLAAVVKSDTVLVDFKMTALDYL
                     RAERRNVKFGERDTTRSWQPTVTVTLADDSEYPVKGIVDFADPLVDPKTGTFGVRAEL
                     SNPNQKLLPGQFTKVKLLLDVRERSIVVPRKALSIEKGGAFIYIIRRDDIAEKRFVQT
                     GPEIGNKVVIERGLGENERVVVEGYHKLVPGVKVHAVEAGDEKAIQALREEEEQ"
     gene            complement(23154..23828)
                     /locus_tag="ACZPB4_09625"
     CDS             complement(23154..23828)
                     /locus_tag="ACZPB4_09625"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HIR1098510.1"
                     /translation="MEVIYEDNHIIAVDKTCREIVQGDKTGDKPLSEMLKAWLKKKYC
                     KPGNVFVGVTHRLDRPVSGVVIFAKTSKALSRLNEMFRVGEVRKTYWAIVKNRPPQDE
                     GELVDWLVRNEKQNKSYAYDTERPNAKKAILRYKLIAHSDHYYLLEIDLKTGRHHQIR
                     CQLAKMGCPIKGDLKYGFDRSNKDGGISLHARSAEFIHPVSKENVRIVAPVPDDNLWK
                     ALSVDQ"
     gene            complement(23830..24576)
                     /gene="fabG"
                     /locus_tag="ACZPB4_09630"
     CDS             complement(23830..24576)
                     /gene="fabG"
                     /locus_tag="ACZPB4_09630"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010536417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HIR1098511.1"
                     /translation="MKLLEGKVAVVTGAARGIGKAIALKFAQEGANIAFTDLVIDENG
                     LATQAEIEALGVKAKGYASNAANFEETHNVVAEIVKDFGRIDILVNNAGITKDGLMMR
                     MSEGQWDAVLNVNLKSAFNFIHACTPVMMKQRAGSIINMSSVVGVHGNAGQANYSASK
                     AGMIGLAKSVAQELGSRGIRANAIAPGFIITDMTAQLSDEVRAEWCKKIPLRRGGTVE
                     DVANIATFLASDMSSYVSGQVIQVDGGMNM"
     gene            complement(24597..25541)
                     /locus_tag="ACZPB4_09635"
     CDS             complement(24597..25541)
                     /locus_tag="ACZPB4_09635"
                     /EC_number="2.3.1.-"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP synthase III family protein"
                     /protein_id="HIR1098512.1"
                     /translation="MFINATGFYVPEERVDNQHFLELSGLTSEWIEQRTGIHTRSKAK
                     EGENINTMSLEAVKDALPKLPYDITEVDLIVSASYSPYDTVATAAHTVQHEYTIADAK
                     ALYLSSACSSFLNALEVVEGYFAMGKASKALVLSADKNSAYYNETDPKAGHLWGDAAA
                     AFFISKERIGEGDAEIVEVYTQGLGHLSKAMEAVHLRPRDGGILMPEGRDVFIQACTY
                     MPKNVLHLLEKNGYTLDNLTYFIGHQANMRIMANIAKQLNLPDEKFLHNIEELGNTGS
                     VSSALVYAQNDKNFKKDDLIAITVFGGGYSTGACLIKH"
     gene            complement(25559..26152)
                     /locus_tag="ACZPB4_09640"
     CDS             complement(25559..26152)
                     /locus_tag="ACZPB4_09640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005641117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HIR1098513.1"
                     /translation="MPMTVSKTRDMLVDVARQLFARMGVDNTTMNDIAQASRKGRRTL
                     YTYFKSKNEIYLAVVESELDQLHKMLVDVASKDLPADEKLLTFIYSRLDAVKALVFRN
                     GTLRATFFRDIWRVEKVRKSFDLREVEIIKGILDDGVKEGIFSMPDTDITALVLHHAL
                     KGLEVPYIRGIMGDNISQRIKRRDNVMNLIFNGIKIK"
     gene            26303..26374
                     /locus_tag="ACZPB4_09645"
     tRNA            26303..26374
                     /locus_tag="ACZPB4_09645"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:26335..26337,aa:Met,seq:cat)
     gene            complement(26572..>27150)
                     /locus_tag="ACZPB4_09650"
     CDS             complement(26572..>27150)
                     /locus_tag="ACZPB4_09650"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HIR1098514.1"
                     /translation="KLFLSAPLVHKPGTYFVYNSLGTYMLSAIIQKVTGEKVINYLYP
                     RLFRPLGIVGATWEESPQGVNCGGWGLYLKTEDLAKMGQFFLQKGKWNDKQLLPESWI
                     EEATTSKIASLPAGMRPENLKMKPKDSDWLQGYGYQMWRCRHNAVRADGANGQYIIIL
                     PEQDAVIAMTANIGDMQAEIDLIWKYILPALR"
BASE COUNT         7306 a         7392 c         5650 g         6802 t
ORIGIN      
        1 atcaagcgga aagactggga ttcgaaccca gggagcggtt acccgctcac cgcatttcga
       61 gtgcggcccg ttcgaccact ccggcatctt tccttgtggt tgacgtgtac aaaagtacat
      121 aaaatatagt atcgttattc tcttgaaagg ctaaaattac tttatcaaat acaaaaaagg
      181 gcattcttca cagaacgccc ctctttaaaa catataacta atacctctaa attacttgaa
      241 ataacgatta tataaacctt caaatccttt gccatgacgt gcctcgtctt tgcacatctc
      301 atgtacggta tcatggattg cgtccaaatt ctgttgttta gccaatgtag cgatacgttt
      361 cttgtcctcg catgcgccag cctcagcttc catacgcttt ttcaagttag tcttcgtatc
      421 ccaaactacg tcgccaagaa gctctgcgaa cttagcagcg tgctcagcct cttcccaagc
      481 gtaacgcttg aatgcctcag ctacctcagg ataaccctca cggtctgctt gacggctcat
      541 ggccaaatac ataccaactt cggtacattc tcccataaag tgagcgttca gaccttccaa
      601 aatcactggg tctacacctt tagcaacacc tagtacatgt tcgtcaacga actgcaacgc
      661 accttctgtc tctactaatt ccttaaattt gcttttcggt tgtttacatt gagggcagaa
      721 ctcaggagcc tcatcacctt cgtgtacata accacatact gtgcaaatcc atttcttttt
      781 catatatcgc aaaattttta ttggttgtat ggcacaaaat taactaaact atccgatact
      841 accataattc atcgatagat taattctatg tgttaatcga taaaaactat ggaacttatt
      901 tttgacagcg attgtttact aagtaaatat ttatttatat ggatacatca aagattatta
      961 gtttattagg agacaaaagt gattattatt taaatcacgt atgtaagact attgataaat
     1021 cgctgcttca tcttccatca cccacttgcg tggacgatgt gtggggcaat tcagatagaa
     1081 acatacagac tctcaatagt ctgcaaacct tgttggggca cggaagatta gctaacaccg
     1141 gatatgtttc tatcctcccg gtagatcaag atatcgagca taccgcaggg tcttccttcg
     1201 ctccaaaccc catttatttc gatccggaga atatcgtaaa attagcgatc gagggtggtt
     1261 gcaacgcagt cgcttctacg ttcggcatac tagggtcagt cgcacgaaaa tatgctcata
     1321 agattccatt cttggtaaaa ctaaatcata atgagcttct tacttatccg aattcttaca
     1381 atcaaatcgt attcggtacg gtgaaggaag catggaatat gggcgccgta gctgtagggg
     1441 ccacgatcta tttcggatca gagcaaagcc gacgtcagct agtcgagatt gccgacgcat
     1501 tcgagtatgc ccatgaacta ggtatggcga ccgtattatg gtgctattta cgaaacagct
     1561 cttttaaaaa ggatggcatc gactattccg cggcagccga tttgaccgga caggctaatc
     1621 accttggtgt cacgatcaag gccgatatca tcaagcagaa gctaccggag aacaacggag
     1681 gtttcaccgc tatcaatttc gggaagatcg atcaaaagat gtacacagag ttaacgacag
     1741 aacatccgat cgacctctgc cgttaccaag tagccaataa ttatatggga cgtgtcgggc
     1801 ttatcaactc cggcggggaa tctcatggcg cctcagatct taaagacgct gtcgtcactg
     1861 ctgtcataaa caaacgtgcg ggtggcatgg ggctgattag cggaagaaag gcgttccaac
     1921 gtccgatgaa agacggcgtg gagttacttc attcaattca agatatttat ttggataagg
     1981 atattactat cgcttagttt gttattgcgt tgagaaaaga aggccgtcca tcaaagctat
     2041 atactttggg gacggccttc aaattttatt tcttcaacca catatccaac cactcaaaga
     2101 atgtgcgttg ccatagaacg ccattctggg gcttcaatac ccaatggttc tcatccggat
     2161 aaatcagcaa ctcggccggt acaccccgaa gaaccgcggc gttaaacgct gccattcctt
     2221 gattagccaa gatccggtaa tccttctctc catggataca aaggataggc gtatcccatt
     2281 tgtccacgaa cttatgcggg gagttcgcga atgtacgctg agccgtagcg ttttgctttt
     2341 cccagtacgc tccacccata tcccaattgg cgaaccacat ctcttccgtt tccagatact
     2401 gcatttccat attaaagata ccatcgtggg cgataaacgc cttgaaacgt ttatcatgat
     2461 gacctgccaa ccaatatacg gagaatccac cgaagctggc gcctacacac cccaagcgat
     2521 ccttatttac atacggttcc ttggctacct cgtcaatagc ggtgaaatag tctttcatgc
     2581 attgtccgcc ataatcgcca ctgacagcct cattccattc caagccaaat ccgggaagcc
     2641 cccgacggtt cggtgccacg ataatataat cattagccgc catgatctgg aaattccagc
     2701 ggtaagacca gaactggcta acagggcttt gcgggccacc ctcacagaac aacaaggtag
     2761 gatacttctt attcggatcg aactgaggcg gatagataac ccacgttagc atctgcttgc
     2821 catctgtcgt cttcatccaa cgctcctcca ccttacccat cgtaagctgg tcgtaaatat
     2881 gcttgttctc gaacgtaagt tgagttaccg tatgatcccc tgtcaaatcg atcgaataga
     2941 tctcgtctcc catgctcatg gaatgacgtt gagcgatcag cttatcgccc agaagagcga
     3001 cagaggcgta atcgtacata ccttcggtca gcggggtaat cttattgcca ttcgccaagt
     3061 ctatctgata aacctgcgac tcgccatgcc aaacgcccgt gaaatagata cgctcgcaat
     3121 cagcgctcca gcaataagag tccacgttgg agtcaaaatc cttgcttacg aatgttttct
     3181 cacccgtctc cagattcatt accatcaagc gattttgatc cgcctcgtaa ccatcccgtt
     3241 ccatacttaa ccaagcgatg ctctttccgt ccggagaata ggtgggattc gtatcatatc
     3301 ccttgttctc ttccgttata ttggtcgttt gcttcgtatt cagatcatat acataaatat
     3361 ccgaattcgt ggagatcgca tattctttac ccgtcttttt gcggctggta taggcaatct
     3421 tgtccgaggt agtgttccaa gccaattgct cgataccgcc aaacggcttc atcgggctct
     3481 caaacaactc gccctccatc acatccacag gattgctgat cgattcgcca tcgaaatcgg
     3541 cgacaaaagg atgcggaacg gtagtcaccc actcatccca atgcttgtac attaaatccg
     3601 taatgataac acctgtcgcc ttatccaaat ccggatattt atcagcggta ctgttcacgg
     3661 ttttcacttg cgagataaac aagacctttt tctcatcggg agagaaagcg aaaccctcga
     3721 tatccttatc ataatcggaa agtcgcttac ggtccgtccc atccggattc atttcccaaa
     3781 gctggctgct accgctctcg ttacataaga aagcgatctt ggttcctcct ttgatccata
     3841 cggcctcgtt ctcagcgaat ccggttttcg tgatttgctt attatccgat ccgtccgcgt
     3901 tcatcacgaa gacctcacgg ttgctcttgt tttccggtac actatagtac gccaccgtat
     3961 acactactct tttcccgtcc ggagatacgt tcataccgcc gatacgtccc atggcccaca
     4021 aagcctccgg ggtcatgcgg ccgtctttga tccggatgtc cgacttcccg ataaggttct
     4081 tatcgccggt ctccttcacg ttcacatccg tagccggatt gcaagcacct aacagtaggg
     4141 atgttgccat aatcattgtt ccgatagatt tattcatgcc gttataatat attacaattt
     4201 gagtgcgaaa gtactaaata taatttatat cttcgcgtta ctaattataa gaactgaaca
     4261 gtatgaataa gatttggtta tttggagccg ctgtatgtat ggtattagca ctcggctcat
     4321 gtaaacctaa acagagcgcg tacaaggctg cttacgaaca ggccaaagaa aaagagtcga
     4381 cagctcctgt tgaggttgta gaacaagagg aagaagttgt tgaggtcgct cctgtctcaa
     4441 aacccagaac ctctacggct accactcgta cggaaaaaat caacgccgct caaggtgagg
     4501 acgccagccg tctgaaacgt tatagcgtcg ttgtcggtag tttcaagaac aagacaaacg
     4561 cttacgcatt aaaagaacgt atgcagaatg atggttacaa cgcagtgttg ggcgagaacg
     4621 agcaagggat gttgcgtgtg atcgtcgcta gcttcgacaa taaagcggac gccgccgata
     4681 gccgtgacgc catcaaggcg aaatacgctc ctaacttcca agatgcttgg ttattggaga
     4741 gagcttatta attgtaagct atcagaaaag ataaaagcgg aaggtctcgt tagcctgtaa
     4801 gaagaatctt gcaggttatc gagaccattc tatttgaagg aaacataagg acataaaaat
     4861 agcccgactt caacagccga gccacttttc accaatctaa tctaacttaa cctaaaacaa
     4921 aaaccatctt tttctttttg cctttctctt cttatatcct aacaaccttt ttaccttaaa
     4981 aacgtaatac ctattcgaaa ttgtataaac tcaaaacatc taaacacata tgatataaac
     5041 gaattactct tcataaaccg gccacgcacc ttctttcgta caaacgaaag ccgctgtctt
     5101 tacagcgaaa tgatgggcct cgcttaagga cttccccttt aagagcgaaa tgattagagc
     5161 ccccgaaaaa gcatcccccg ccccgaccgt atccgccacc gtgacctccg gcgtgggcaa
     5221 cgtagagatc tcctctctcg tataaatcgt actatgggag ctccccgcag tcaagacaaa
     5281 catccgaagg ccgtatttct caataaacca taaagccact tccctctcag ttccattcaa
     5341 gccgaataag tcccgaagaa cgttaaactc ctcatcattc accttcaaca cattcgctaa
     5401 gtacaaagac tcctcgatca actccttatc atagtatcgc tggcgaagat tgatatccag
     5461 caaacgataa gcgtctttcg gcgcaaacga cgagatcgct tgtatcgtct cccgggactg
     5521 acgggaacgc tgggctaatg taccgaaaca aatagcgtcc gctttctccg ccaaatcaat
     5581 cgcgtcggat gtaggcgata tatgatccca agccactcgc tcatgaatcg tataagtagg
     5641 gataccttct cgtaactcta cctgaacggt tcccgtcggg taaggcactt tctcgatcaa
     5701 atgctggata tgattcttat ccaactcatc aacgatctct ttacccaact catcatctcc
     5761 gacagcgctg atagcatatc cctcagcacc taggcaagac gcatgataga caaaattaat
     5821 cggggccccc ccagcctttt tcccggaagg aagcatatcc cataataatt ctccaatccc
     5881 aacgacaatt ggtttacgtc ttgattcagt cacctgttcc atggtctttc tattaaaaac
     5941 aactttcgta cttatcgaca ccgcaaaagt atatcatcgt tataaataca acgataacta
     6001 tagctacaag ataaatcaca caagttacat aaaagattta ttttcaaggg acaataacag
     6061 acgttacccg tatgtaacat ctgtacaagc agcatcctta caaagactct ataaactcgg
     6121 ttggcgttat attataaacc gctttaaagc atttggagaa ataggccggc gagccgaatc
     6181 ccgtggcata agcaacctcg ctaatcgttc cggatcgctg cttcaatagg gcggatgcct
     6241 ttttcaaacg atagttacgc aaaaagtccg taggggtaat cccggacaac tccttcacct
     6301 ttcgatataa atgcacacgt gacagaccca gtttctcgct gcctttctct atactgaaat
     6361 cgggatcgct ataattctcc tctatcaaag cgataaactt acgcataaac aaatcatcca
     6421 gactctctac cttccctttt gtctcgatgg aaagtcccgc aggcgattga gactctttca
     6481 agaaaacctc tcgcaaacga ttacgttctt ccaacaattt aatgatacgt aatttcacga
     6541 tctcaatatt gaacggtttc tggatatatt catccgctcc cccctcaaat ccatacaagc
     6601 gttgactgtc atccgaaaga gccgtaagca agattaccgg gatatgactg agggccatat
     6661 ccgacttaac ccggcggcaa agctcgaagc cattcatctc cggcatcatc acgtcactga
     6721 cgaccagtga tacattttcc ttcaatagaa tatccaaggc cttggcacca ttctccgcta
     6781 caagtacatt aaaattcccg gacaactcat gctgtaaata agcgcgaata tcccaatcat
     6841 cctcaacgat caagatcata taatcatatt tcttattcaa cgtttcttga acttgggata
     6901 tatccaaatg cgctacacca gaggacgatt ctgtcgcatt cgacagaaag acacaagatt
     6961 catcaaaatg agatttacct ttcggaatct gaacggtaaa cactgtccgt tcgccttgct
     7021 cgctttccac gtggatcgag cctttatgca taaggacaaa ttcccgtgtc agatgcagtc
     7081 cgatacccgt tcccggagca tagctttgcc cgcttgtaaa aaagcgctcg aatacggagg
     7141 ctaggttttc cgggggaata ccctctccat tatcttccac cgataagaca acctccgtct
     7201 cctcctcccg caaacgaatc gtaatcttcc cctgctccgg ggtaaactta aaagcgttcg
     7261 aaagcaagtt cgttaatatc ttctccattt tgtccgtatc cacccaaaca aaaagagaat
     7321 ccatttcatg caggaaggta taatcaattc gcttactctg ggccagagta tcaaaataag
     7381 atttcacctc ttggataaaa aaaaccaaat ccatcttagt aacccgcaat cccatcttat
     7441 tattctctat cttccggaaa tccagcaatt ggtcgatcac acgtttcaag cgttccgcat
     7501 tcttcttaac gatgcggata tcatctgcga aagcgcctgc cggagcatct tgcgccatct
     7561 tgctcaaaga ccctagaatc aaggttaaag gagtctttat ctcgtgagat acattcgtaa
     7621 agaactgcaa tttttgtgcc gtgacttgct cgatacgctg gttcgctacc gagagttcct
     7681 ctttctgttg ttgtaccaaa cgatttttct cattcaacaa atgattcttc tggcgcactt
     7741 tacgattaat ataaaccgtg taaatagcgg agccccccaa taaaagcgcc aatatcaaga
     7801 taataatcaa ggaactataa agaaagttat atttcgagag caattgcgac aaattcgcac
     7861 gctgtttctc gatctgacgt tgatattcta ccaaccggtc tgattgtaaa taaagggtac
     7921 cggcattggt cttatcgatc atagcggtgc ttaacgcata ctttttcgta taagcctgtc
     7981 cacttaagat ctgccaagct accttaatag ccaccccacc acctgtcgga taataaaaag
     8041 aggcatccaa cttaccctgc gcaaccgcct ccacgcccaa gcctcctccc aagagtccat
     8101 ccacgcctat aaattccacg tgccccacca gcgacgaatc tcgctcctca atcgcctcac
     8161 gggcccctaa ggccatcata tcattatgag cgaaaacgat atcgacatcc tctatggaat
     8221 ccagcttcaa gacttcctca taggcattct ccttatacca atacccatcc aactcccgga
     8281 tcttcacatt cggatcaata gacatcgcat cgacaaaacc ttgatgtctt tctgtagcgg
     8341 aggaagagcc tcttcgtccc catatctcta aaatcgttgt ctcccccttg atcaaggagc
     8401 tgatgtacat tccgatcgaa cgaccgatct cgtaattatc cgctccaata tacgtcgtat
     8461 attcatcgct attaattttc cggtccaata tgatagtggg aataccagcc ctgtacgcct
     8521 caacagcgac aggcgtaaca ggctcggtct cattcgacga tataatcagc aaatccacct
     8581 ttttcttgat aaaacctttt atctggctga tctgagtatc attatcctga ctagcatcca
     8641 ttacgaccaa ctcgatctcc ggatgattta aagcctctac ttccatatca cgtatcatgg
     8701 attgacgcca aatatccgtc atcgagcatt gagatacacc gatgacatat ttcttttctt
     8761 ttttaccggg cgaacaggca aagcaaagaa taaggaatag ccaaagcagg atataaagcg
     8821 ggtttccttt catgtggtat atttaattcg atcgtttatt ctacaaatat acgaaaacta
     8881 ttccgaaatt acccccaaac aagtcaaggt atcttttaac aacggggtaa atctatggat
     8941 accgatttca ttcaaatgat cagcgtccct atagcaagaa tcaggtaacg gtacagccgt
     9001 ataattcaaa taaaagaccg ttttatcatc cacgtattcc cgagccaaag aatccgtcaa
     9061 ttctcgataa ctcgaaggaa cccgttccat atattccgtg gaaacagggg cattgtacaa
     9121 aataagagac agatcccgct tcttacattc ctctacgatt cgccccaaca tctcttgttg
     9181 aaatgaggat ggcaataaat aagcaccctt atcatcatag taatgacgat cgataataac
     9241 gtctagtgtt cccccggtcg cccccgtgaa aatacgctcg atcacattcc ttttaatctc
     9301 agctacgcaa ttcttgaacg gaacgccaaa ctcatacgaa tacatgacct ccttacgggt
     9361 taccggcgaa acagcctcct gtaccaaaag tcgcaaatcc tcccgctcct ttagatgggg
     9421 ataaatagac atataggcag gaaactcatc ttgataggaa tcatcggcca cggtaaacgt
     9481 gtggtaacca aaccccaata tcacggtttt caaatgggga aggtaaggcg ctttcaagca
     9541 taaatcgata taggtattga aataattctc actggattta gcgtcattcc tcgatttccc
     9601 cagcatatcg gcggatatcg aatgtaaagg atgggaatcg cccaaaatca atacctccac
     9661 ttccggatca cttttgaggc tgggtacgct tatatgaaaa taagagcgga tcagcaggca
     9721 actaagcaac cctaaacatc ctaccacccc taaataccgg aatatagcta taaagaacct
     9781 tctcatactt atcagaattg aaaataaatg aaaccttgtg gattactggc gtcgaaacca
     9841 tagatgataa tcagcaatac cgtatagata acataccgaa ccggaaggct caggtcctct
     9901 atcatcaacc catgcgcctg ttttcggccg atccattcca cgacgaacat aagagccgtg
     9961 aaaaagaaac atttcttcag caggagttgc ccgaatccca agcccacaag ctgaggagcc
    10021 gagaataacg agacattgaa catccgctcg agatacacag ccgcttggga tatatcttcc
    10081 gaccggaaca gaatccatcc caataagacc agcaaaaacg tagctcccat ctgtgtcaat
    10141 tccttcacag agggaaggaa actgttttcc gccacggaat ctctatacct cctattttga
    10201 cccaacaata acaatggcag aaacaacaat gcatgatacg ctccccatgc cacaaacgtc
    10261 cagttagccc cgtgccagaa cccacttacc aagaaaataa caagggtatt ccggaagctc
    10321 ttccatttcc ctgcccggct tccccctagg ggtatataga tataatcccg gaaccaagtc
    10381 gtcaaagaga tatgccaacg ccgccaaaac tccgctatat cccgggagaa ataaggatac
    10441 ttaaagttct gcataaggtc tatgccaaac aaccgggcac agccgatcgc tatatccgag
    10501 tatccggaaa aatccccgta aatctgtatc gtaaagaaga aagcccccag aaacaaggta
    10561 ctcccatcca acgtctggta attctcaaac acaccgttca cgaacaaagc gcagttatcg
    10621 gcaaccacca ctttcttgaa aaatccccaa agcatctggc gtataccatc caacgccaga
    10681 tcacaatcga aattacgagg ccggagaaac tgaggtaaca aatgggtagc ccgttctatc
    10741 gggcccgcca ctaattgggg gaagaaactg atataagcga agaatgccac aatatcatga
    10801 gtcgccttga ttttaccttg gtaaacatca atcgtatagc tcaaagcctg aaacgtataa
    10861 aaactgatcc cgacagggag caagatattc aacgtcacgt aatcggcatc ccagcccaat
    10921 aggtgaagga catttaccaa attctcggta aaaaaatcaa agtacttaaa tacacccaag
    10981 atcgaaaggt tcagtaaaat attaccggca cttatccact tttggaccga ccggttgcca
    11041 gcgcatttct ccaaatagac tccactcaag taactgcata acgacgtaaa caggatcagc
    11101 agcaaaaagc gccagtccca ccatccgtag aacaggtaac taacagctac cacaaataga
    11161 ttttgccacc gcaaagactt gaaaacaaac cagtaaccaa agaaaaccaa tggcaggaat
    11221 ataaggaact ctatggaatt aaataacata aatatttaat tttcagactc aagaatatgt
    11281 atcatcaagg cgcaaagata aggaatatca agtattgacc aataaatatt tcgtatattc
    11341 gtagctcaga aatacaataa gatacagaga tgaagataat caacgaacaa ttactcgacg
    11401 agacccaggc caaagccttg cagtctcccc gcctgcgaat gaactataat ttccatgaga
    11461 aattggatga tccgatcaat cggttactga atgccatgga gcccggtacg tatttgcgtc
    11521 cgcaccggca tttaaatccg gcgaaagacg agatcttctt gttgctgcgt gggaaggtag
    11581 cggtattctt gtttgacgag gaagggaata tcacggagaa aacgatactg aatccaaagg
    11641 aaggcgctta tggagcggag atcaaggccg ggacatggca cgggcttctg gtactggaat
    11701 ccggatcggt tatttatgag ataaagcaag ggccgttcgc gccgctagca ccggagaacc
    11761 tagcgccttg gagccccgag gcggaagata cggagggagt aaagaagtat ctggaatggc
    11821 tcgagagcca aatatgatcg atgatacttt tagtataaca agctagcgat cagcctcgta
    11881 taacaagagc tatccgatgg ttttaacaat gcccattgta aagaccttac gatgcccatt
    11941 ataaggagct tacaatgggc atcgttacct ccttataata ggcattgtta ttatttctgg
    12001 aaaaccttcg tcgatttaat catcacgtcg tgtaaaggac gatcgttctt atccgtcttt
    12061 accacggaga tcttctctac gatatcgaag ccttccacta cctcgccaaa gatcgttacc
    12121 gagccatcca gatgcggaac gccaccgatc gtcttataaa tctcacgccg ttcggccggg
    12181 atcactaccg ggcctaatac cgccaacgta tcttccacca agatggacgc acgggcatgt
    12241 aactcattct ccaaggaatc ggcggccaag gaaggatctt gctttttcag ctcatcccgg
    12301 aatttatagt acaaccagtt gcggcggatc tcattgatac gagcctcttt ctccgcaagc
    12361 tccttgtcgt ccaagacttt cccttgcaca agacagaact gcgtaccggc ggaggcacgt
    12421 tccggattca cggcatcgat ctctttcgcg tcgatcaaag cgcctttctt attaaaatga
    12481 ttgggtaata tctcggcggg aacggtataa ccaccatcgc catccccata caaggcaccc
    12541 ggctcatgcg ccttactctc cggatcacca ccttgcacga caaactcctt gataacacgg
    12601 tggaaaagca taccctcata ctcgttcgac tggcagagct ttatgaagtt atcccggtga
    12661 agaggcgtat cgtcgtatag caggacggtg acgtctccca tcgtcgtctt gattttcaca
    12721 tatacgggtt tattcgggtc caaaggctta tccccacaag ctaccaacgt gagcaagagc
    12781 aggaacagcg agaaaatttg tcgtttcata cctgttttat ttatcggatt aagtagttac
    12841 aaagccggtt attcctccgc atagatcaac atctggcaat tcttgcagtc gaagcgcaaa
    12901 cgcaagagcg tctccttata gcgcaggaag taaggctctt tatagggaga cttctgcttc
    12961 tggtaggtag ggcaccatcc catactgtac cgcaggcaat gtttcgtgaa catcaaaggg
    13021 acatccttcc ggggagacaa ctcgaaagcg tcttccacgg cagtcacgcc atgtgcctta
    13081 taaaaggcac cagccttgct attggagaca ttccctaaat aagtcagacg tttctcgggg
    13141 aaagggattt ccgttgcctc gcctacacac ggctttaccg gacgagcctc ttccctgcgg
    13201 taacgaatcc gccgggtaga gataagcctc tccacccctt gcctacgcat ctcggccaat
    13261 aaagaagaag ggacaaacca gttatcggac atcgccacgg caacttcctc cgcctcgaaa
    13321 ggcgtgttcc ccaacttaga gagctgggta cggatattct ccgcttgatc ccgccgggcc
    13381 ggttctttct cgaacggctt ggtgagcatg atacgggctc ctgtctcgtc cgccatactt
    13441 aacgtgaagc caaaggcgtt atcttgaaat tccatccgga cagagagttt ccgctcggcg
    13501 gatggcttgg atagcagttt atcaaactct tgatcgaaat tccggtacaa aggcatcttc
    13561 ggacggatcg ccgggcgatc cagcgtaaag atccggttcg cctccacacg gtttacccgg
    13621 aaaccctcca actccccttt ctcgttgaag aaggtaagcc cgtctccgtt attcaattgt
    13681 ttcagtccgg cgatcgtgaa agagtttcct ttcagttcct tcaccgtacc caccggttca
    13741 cccaaggact taggcgtatc aaagctggtg atatccttcg tgcgctcctt ccataagaaa
    13801 ggcgtgaaac cccggttgaa gcttttctcc gccacaggct ggaatgtgta agtgctatgc
    13861 ccggccgagg cacgacggta ttccggccga cgagccaaga tagcgtccag tttcttccga
    13921 taccaagccg ttacgttttt cacgtaagat acatccttca aacgaccctc gatcttcaag
    13981 gaagagacac cggcatccaa caactcctcc aagtattccc cccggttcat gtccttcaag
    14041 gataagagat gcttacccga tacgatctcc ttcccgtccg catcgatcaa gctataaggc
    14101 aggcggcaat actgggcgca ttccccccgg ttggcgcttc gtccgctcaa ggcggcgctc
    14161 aggtaacact ggccgctata gcttacgcac agcgccccgt gtacgaagac ctccagaggc
    14221 acggtcgttc gctcggcgat ctcccgtatc tggttcagtg atagctctct cgccaatacg
    14281 acttgcgtga aacctgcctc ttgcaggaat ctcaccttct ccagcgtacg gttatccgtt
    14341 tgcgtactgg cgtgcaaggg gataggcgga aggttcaact gggtgatacc catgtcttga
    14401 acgatcaagg catccgcccc ggcctcgtaa agttgccaga tcatttgctc ggcctctgcc
    14461 agctcctctt ctttcaagat agtgttcaag gccacgtaaa tacgagccga atagagatgg
    14521 gcgtaatcgc aaagctgccg tatatcgtcc agcgtattac cggcggcggc acgggctccg
    14581 aacttcgggg caccgatata cacggcatcg gcgccatggt taatcgcctc cctaccgcaa
    14641 atcagatcct tagcgggaga taacagttct atcgaacggg gttcttttct catttacaag
    14701 cttcctagtt ttttaatatc ttcccggcgg aacggggtct cttggtatac gtaatagttc
    14761 agccaattgg tgaatagcag gttcgcgtgc ccccgccaac gtaccaccgg gccttgcgcc
    14821 ggatcgttat tccggtaata attacgaggc ttgttgatgg gcaatccctt ccccaaatca
    14881 cgcatatact catcattcag cgtatagggc gaatactcgg aatggccggt gatgaagaat
    14941 tcccgtccgc cacgagccat cgccatatag acgccggatt cctcgctctc ggacaataag
    15001 gtgagctcgg gcaccttcat gatatcctct cggcgaatct cggtatgacg gctatgaggc
    15061 acgaagaact cgtcatcgaa cccccggaag atcggaacaa acggttcccg gagcgaatga
    15121 cggaagacac cgaacatctt ggccggcaaa tcatatttag gcaccccata gaaatggtat
    15181 agccccgctt gcgccgccca gcagatatag agcgtggagg taacgtgcgt acgggcccaa
    15241 tcgaatatct gcgtgatctc ctcccaataa ctaacttcct cgaaaggcat ctgctccacg
    15301 ggagcgcccg tcacgatcat cccgtcgtag aaatcatccg ccatctcatc gaaatcctta
    15361 taaaattcct gcatatgctc gatgggcgta ttcttcggcg tatgtccctt gatcttcatg
    15421 aaatcaagtt ccacttgcag gggtgtatta ctgaggaggc gaaccaagtc cgtctcggtc
    15481 gttatcttaa ggggcatcaa attcaatacg actacccgaa gggggcggat atcctgctcc
    15541 gacgcacgca aggaatccat cacgaagata tgttccttct tcagcagctc gatagccggt
    15601 aagttctttt gtaaatttaa tggcattttc tatctctgat tattatatga gcgcaaagat
    15661 aatgagaatt ttctcattat cgcttatact tcgccaccat gatcacgggg ttatcctcct
    15721 cgtgcatacc cgcggcgatc tcctttaact tgcctttgag gtgtccttct tgataggcct
    15781 cgacaagttc gggggtattt atccgccacg tgaaggcgat ctcgtcgtta ttgaagaccg
    15841 tgaggtcgaa aatctcgtcc acgaggttgg cgatcggtac ttctttcgta aaatcatcgt
    15901 tatataggac atactcggat acttcctttg tctccctatc gtacaccaaa tcggttctca
    15961 tcaaccgata gtaggtatcc atcatcgcca agttcaactc tttctttacg gtctgcataa
    16021 aacaatagcg atccgtaacc acacccggga aaagaaagat ctccgggctc atggattgaa
    16081 tagagggagt ccttacgata aaaggcttta atccctcggc ggacgagtag gtgtagaccg
    16141 tatcgcaaga tggctccgta agtagccaac gaacctcgta agggacgata caagggttat
    16201 taaccatacc tatgcccttt tcgtcgaaca atacttgcga cacctttttc tcaaaaggga
    16261 cttttatttc ttctaccaca ctcccatctt gcttggatac tatcaggaat atattcctag
    16321 gctcaagatc ctgataagcc ccattgaaat tacgcccact actagcatct tggcagatga
    16381 agtgatccct gtcaaaattg aagatcgctt tataataaac ccatgatttc gtatcctcgt
    16441 cttctccttc cttgaacgtg aagcttcgct tgaaattccc aaacaagtca taagtcatta
    16501 tctttctttg ccgcagatta ccaacaaaca gttctccttt ctcatcgtcc agatagatgc
    16561 cattcgttgc ggcatactcc tcgttcccct gccctttccg attgatatgc caaatagcct
    16621 tacctttccg gtcgtaaata aaaatgtcac catcggcagc aaacatattc cgtatgatca
    16681 tcacatcctt cccgatcgct tgcaaccagc ctagcgtcac gaactcgtcc gtagtctcca
    16741 acggaatata ttccacgtca aaaagatctt gcaagatcag ttcctttttg ggataatcct
    16801 tcgatacgtc caccacgata agatcctctt tctcttgggt agaagaggta ccgcaaccaa
    16861 ccatacctcc cgttaataaa aacattcccg ccgctatcaa gctctgtctc ataatagtct
    16921 tttcttttag tttaaattta aggataaagg caaataacat tcaccttgcg caatataggg
    16981 aatttttaat ggctacgcaa agatttgttc gaaaaactcg taaatatctc attatttaat
    17041 ggttattata aataagaaaa ccaatggact ccatcctata actcaatggg atcttgttcg
    17101 tattccattg agttatagga tggagtccat tggtttatag attgatatcc atatatctgc
    17161 tttaggtata aggattagaa ccctccccct aaagccttat acaggtatac caccgacagc
    17221 aactcatcca gcacggcatt gttcaaaccg atctgggcgt ccagcaaacc acgctgggca
    17281 tccaatacgt ccatgtagct gatgacaccg ttgatgtatt gcagttgggc gagttccaga
    17341 tatttactgg cggaggcttc cagattcatg cgggaagcac ggatctcctt caccttgcgg
    17401 acggtcacga tagcgttgtt cacctccttg aaagcgccta atacgctctt ttcataacta
    17461 tagacctctt gctcgtaacg agccttcgcc gctttcactt tcgccttgtt cttccccatg
    17521 gcgaagatcg gctgcaacag gcttccggcg ataaaaccag ccggactctt caagatgctg
    17581 cttaactcat cgctctcgaa accgtaatta cttgtcaaac ggatcttcgg gaataagtcc
    17641 gtttgcgcca cacctacctg agcgttcgcc gcccgaagct taaactccgc ttgacgcatg
    17701 tccggtcggc gctccagcaa agaagacggt aagccgatcg gtaaggcatc cggcaagtgc
    17761 tggtcgctca aggaaagacc acgggggata tcatccgtat actcgcccaa caacatgctg
    17821 aggtcgcttt ccttgatctt gatctgacgc tccagcgagg ggatcaaggt ctcggtacgg
    17881 gccaactcca cttgggcttg gttgtaagcc gtctcggaag taagtccgcc ctcatagcga
    17941 agcttcgcca agcgaacacc ctcacggcgt gcgtccaaag tttgctgtac gatcgacaac
    18001 tcttggtcca aggcgcaaag ttgataataa ttggcggcaa cctcggcgat gatggtcaat
    18061 cgcaaggcac gttgtccttc cacggtctcc atataggaag cgatggctgc ctcattcgcc
    18121 cagcgaaggt tgccccataa atctaattcc caagacaaag tcagcttcgc cccaaattct
    18181 ggatcgggct ttgggttatc ccctccataa ttcaagcgtt ccttttgcgc atagatattc
    18241 gctcccacct ccggcagcat actcgcgaaa gagatccgct tggcggcgat catctccttc
    18301 accttggcgg cggcgatctt catatcctta ttattatcca gcgcctttct gatcagatcc
    18361 ttcaaggcct catcggcgta aaggctctcc catgggatat tctccacgga tgccgtatcg
    18421 gtcgtatccg tataagcctc gatccggtcc ggcaggttca actccggacg tacgtaccgc
    18481 tttccgatct tgcaggaaga gaacgccagc atagaaacga cgaaagcggc tatatagaaa
    18541 ttctttgtca tcataatttt ccgtttttgt gtctctttaa aatagaggtt accacttctt
    18601 tcttttgagc gatacgttcc atacgcatct ttccctttat cttatagatc aaaacaaaga
    18661 agaagggaac caacacgata cctaccgtaa tcgccaccag cataccgaag aacacgcccg
    18721 taccgatact atggcgggaa gctgagcccg gtccgctggc taacaccatc ggaagcatac
    18781 ccaacacgaa ggccaacgag gtcatcaaga tcgggcggaa acgcatctgg gcggcatgga
    18841 tagcggctct caccacatct accccgttat ccacctgtac cttggcgaac tcaacgatca
    18901 agatagcgtt cttcgccgcc aaaccgatca aggttaccag accgatctga taataaatat
    18961 cgttctccaa ccctgtcgcc cagatgccca agtaggcgcc cagcgtagct accggcaagg
    19021 aaagcaatac ggcgatcggc acgatccagc tctcatactg agccgccaag aacaagaaga
    19081 caaacaagaa gaccaacgcc aagacaaaac cagtctgccc accggcctgt ttctcttgat
    19141 aggaaagacc gctccactcc agaccgatat tctcgggcag atgctcccta gcgatccgtt
    19201 ccatcgcagc catcgcctca cccgtactat atcccggagc ggctacggcg ttgatcgagg
    19261 ccgtggtgaa catattgaaa cgcttgatcg ttcccggacc ggtcgtatat tgggtcgtgc
    19321 ccaaggcagt caatggaacc atcgccccat ccttactgcg gacgaagaac aaatccagat
    19381 tatcccgggt ggcccgataa ggcgcctccg cttggatata tacacggtaa atacggttga
    19441 acatattgaa gtcgttcacg tacacggagc ctagataagc cttcatggtc gagaagatat
    19501 cagacaacgg gatgccgagg aacttcgcct gatcacggtc cacgtcgaaa tacaactgcg
    19561 ggatctcgct ctgcatggcg gaagacacac cttgaagctc aggcgcttgc gaagcgtaat
    19621 acaggaaagt atccgtggca cttaccagat tatcccagct agcgtctccc ttagcctcca
    19681 actgcatctc caagccaccg ctctcaccca aacccgggat taccggtgga cggttcacat
    19741 acgacttagc ctcggggtaa tagtagaatt cccggcgggc atcggccatc acgtcctcta
    19801 ccttcatgcc ggaggattta cgctcttccc acggtttcaa gatcaccgtc agcgtggcac
    19861 gcccttggtt cgtaccgaca cggggactgc tacccgttac attctgtacg taggccacgg
    19921 ccggatgatg gtcgaggaac tcgatcgcac ggtcggttac ggcacgtgta cgttccaagg
    19981 tagtaccctc gggcatctcc agctctacag tgaagaaccc ttgatcctcc tccgggataa
    20041 agctggtagg caacatccgg ttcaagacaa agatggccac cagtaccatc ccgaaccctg
    20101 ccaagatacg gcggggatta gcgatagaga tacgcaacaa cttcgtatat ttcttatttc
    20161 ctttcgccaa ccacagattg atcttacgga aaataaacgc tttcttctta tgagacggac
    20221 gcaagatgat ggcgcacatc gccgggctca acgtcaaggc cactaccgtg gacaacagca
    20281 cggaaaccac gatcgtaaca gagaactgac ggtacagctg ccccgtgata ccccccaaga
    20341 aactcaccgg cacgaacacg gcagccaata ccatggaggt agcgatcaaa gcaccagaca
    20401 attcccgcat cgccttatgc gtagcctcac gggcagtcac acgctcctcg gccatgatac
    20461 gctccacgtt ctccaccacc acgatagcgt cgtccaccac gataccgatc gccaagatca
    20521 atcccagcaa ggttagcata ttcaacgaga aaccgaagat caacatgaaa ccgaacgtac
    20581 cgatcaagga gatcgggacg gcgatcgtcg ggatcaaagc cgcacgccag ttctgtaacg
    20641 agaggaacac tacgagaacg accaagaaaa gggcctcgaa caaggtttta tacacctcgt
    20701 gcacggattg tgagatatac tccgtcatat cgaacgggaa attatactcc aagccttccg
    20761 ggaagttctt gctgatatcc ttcatcgcct ctttcacctt cgtggcgacc tccagagcgt
    20821 tcgcccccgg caacatatag atacccaaga tagcggcgtt cttcccattg atcccactct
    20881 ccgtagaata agaggaagcc tccagcgata cccgggccac gtcgctcatc cggacgatcg
    20941 agccatccgg gtttgctcgc accacgatat cctcgaactc cttcacggta gacaaacgtc
    21001 ccggggccgt gataggcaag gtgacatcca catccagcac gggctgctta cccagctcgc
    21061 ccgccgccga ctcccggttc tggtctttca aggcatcttg caaatcactt accgtcaatc
    21121 ccatgttggc caaccgatcc ggatataccc agatctgcat accgtaataa cggctaccga
    21181 tattcgatac acgacctacg cccgggatac ggcgcaatac gtccaacacg ttgatcgtgg
    21241 caaaattact cagataaatc tcatcgaact tcggatcgtc ggacatcaag ctcaaggtca
    21301 tcagctggct aggagcctgc ttctcgatcg tgataccatt ttggatcacc tcggcgggca
    21361 aacggctctc ggccagtttc acacggttct ggatctcgac agccgccaag tccgcatcgg
    21421 cggatacatc gaaggtcacc gtaatattca agctacccga gttcgagcta ctactttgca
    21481 tatagatcat acccggcgta ccgttcagct cctgctcgat cggggtagcg accgcttgag
    21541 acaccgtcaa ggcgctcgct cccggatacg tggcgctgat cttcactaca gggggcgtaa
    21601 tctgcggata ctggtccaca ggcaacaatg ccagtccgat gattccgaca atcacgatca
    21661 gtatcgataa gacggtcgaa aagacaggac ggtctataaa gaatcccggt ttcattgttc
    21721 ttcctcctct ctaagcgctt ggatagcctt ctcgtcgccg gcctctaccg catgtacctt
    21781 cacgcccggt accaatttat gataaccctc taccactact cgctcgttct cgcccaagcc
    21841 tcgttcgatc acgaccttgt tgccgatctc cgggccggtc tgcacgaaac gcttctcggc
    21901 gatatcgtcc ctacggatga tatagatgaa cgcacctcct ttctcaatcg agagcgcttt
    21961 ccggggaacg acgatcgaac gctctcggac atccagcagg agcttcactt tcgtgaactg
    22021 tccgggcaat aatttctggt tcgggttgga tagttccgca cgaacgccaa acgtaccggt
    22081 cttcgggtcc accagcggat cggcgaagtc cacgatacct tttaccgggt attcagagtc
    22141 gtccgctaag gtaaccgtca cggtaggctg ccacgaacgg gtcgtatccc gctcgccaaa
    22201 cttcacgtta cgacgctcgg cacgcaggta atccaaggcg gtcatcttaa aatcgaccaa
    22261 taccgtgtcg ctcttcacga cagccgccaa tttcgaattg acacccgggc ccaccaaagc
    22321 gcccacatcc acgaaacgct cactgatata cccggacagc ggcgaggtca ctaccgtata
    22381 gctcaactcc atctccgctt gatccagatc cgccttgctc atggcgatat tcgcctcggc
    22441 gtcttccaga gcggccgtgg cgttatccaa atccagctgg ctggcggcgt gttgctcgta
    22501 caacggtttc aggcgttcca catcacgccg ggccttggcc gcttgggctt ggcttttctt
    22561 cagttgggct ttcgccttct ctaccctagc acgatattta tcgggattaa tcataaacag
    22621 gggctcattc tgcttcaccc gtttaccttc ctcaaacaac attttctcta ggaatccctc
    22681 cacacgggca tgtacctcga caaagctggc ggcacggata cgtcccacgt actcaccata
    22741 aatctgcacg tcttcttttg agggtttgtc tacgatcacg atgggcaatt gctgctcttc
    22801 cttatggtgg caacccgtca tcgctactac aagggctatc aagataacct gtacttttgc
    22861 caatcttttc ttgctcattc tacctatata aattacttat gtcacatttg tcatttaaga
    22921 aagaaagaat cattccattt ttctcgagga catcgataat taacgttact tcacttaata
    22981 acaaaccgta tagcgtttat gttaacattt atactaaaat tagggcatat ccaactgggg
    23041 aataaatcca caaccagccg ggaaagtcta cacttaaaaa taaaaatccc ttcgaatgaa
    23101 atgctttttc catccgaaag gatttcacag ataccagatc ttcatctatt atcttattga
    23161 tcaaccgaca acgctttcca caaattatcg tccggtacgg gagcgacaat tcgcacgttc
    23221 tcttttgaaa ccggatggat aaactccgca ctacgtgcgt gcaagctaat gcctccatcc
    23281 ttattggaac gatcgaaacc atatttcaga tctcccttga tcggacatcc catcttcgcc
    23341 aactgacagc ggatctgatg gtgccgcccc gtcttcaaat cgatctccaa cagataataa
    23401 tgatccgaat gggcgatcaa tttataacgc aggatggctt tcttggcatt cggccgctcg
    23461 gtatcgtaag cgtaactctt attttgcttc tcgttccgca ccagccaatc caccaactca
    23521 ccctcatcct gcgggggacg gttcttgacg atcgcccaat acgtcttgcg cacctcaccg
    23581 acacgaaaca tctcgttcaa gcgagagagg gccttgctcg tcttggcgaa aatcacgacc
    23641 ccgctcaccg gacgatccag acggtgcgtg acaccgacaa agacgttacc gggcttgcaa
    23701 tacttcttct tcagccatgc cttcagcatc tccgagagag gcttatcgcc cgtcttgtcg
    23761 ccttgcacga tctcacggca ggtcttatct accgctataa tatgattatc ctcgtaaata
    23821 acctccatat tacatgttca taccgccgtc aacctgaata acctgtccgg atacataaga
    23881 agacatatcc gaagccaaga aggtagcgat attagccaca tcctcgaccg ttccaccacg
    23941 gcgcaaagga atcttcttgc accactcggc acgtacctcg tcagacagct gagcggtcat
    24001 atccgtgatg atgaatcccg gggcgatagc gttcgcacgg atgccacgag aacccaactc
    24061 ctgagcgaca gacttagcca agccgatcat accggccttg gaagcggagt agttagcttg
    24121 tccggcgtta ccatggacac ctacgacaga agacatattg ataatgctac ccgcacgttg
    24181 cttcatcatg accggggtac aagcgtggat aaagttgaaa gcggacttca agttcacgtt
    24241 caacacagcg tcccattgtc cctcgctcat acgcatcatc aagccgtctt tcgtgatacc
    24301 ggcgttgttc accaagatat cgatacgtcc gaaatccttc acgatctcgg ccaccacgtt
    24361 atgagtctct tcaaagttag cggcgttaga agcgtatcct ttcgccttca cgcccaaagc
    24421 ctcgatctca gcctgtgtag ccaagccatt ctcatcgatc accagatccg tgaaagcgat
    24481 gttagcgccc tcttgggcga acttcaaggc gatagcctta ccaataccac gagcggcacc
    24541 cgttacgaca gccactttac cttctaatag tttcatatta ctcaaatttt ttaatatcaa
    24601 tgtttaatca agcaagctcc cgtcgaatag ccaccgccga ataccgtgat agcgatcaag
    24661 tcgtctttct tgaaattctt atcgttctgg gcatatacca aggccgagct tacggaaccc
    24721 gtatttccca gctcctcgat attgtgcaaa aatttctcgt ccggcaagtt caattgcttg
    24781 gcgatattcg ccatgatacg catattcgcc tgatggccga tgaaataagt aaggttatcc
    24841 agcgtataac cgttcttctc caacaaatga aggacattct taggcatata ggtacaagct
    24901 tggataaata cgtcacgccc ctccggcatc aagataccgc cgtcacgagg acgcaagtga
    24961 accgcctcca tcgctttcga caaatggccg agaccttgcg tgtagacctc tacgatctca
    25021 gcgtcgccct caccgatccg ctccttggag ataaagaaag cggcagcggc atcaccccat
    25081 aaatggcccg ccttcgggtc tgtctcatta taataagcgg agttcttatc agcggaaagc
    25141 accaaagcct tggaagcctt ccccatggcg aaatatccct ccacaacctc caaggcgttc
    25201 aagaaagaag aacaagccga ggatagatat aaagctttcg cgtcagcgat agtatactca
    25261 tgttgaaccg tatgcgcggc cgtcgcaacc gtatcataag gagaatacga agcggagacg
    25321 atcaagtcta cctccgtgat atcgtaaggc aatttgggaa gagcgtcctt cacggcctca
    25381 aggctcatgg tattgatatt ctccccctct ttcgctttcg agcgggtatg aattcccgtc
    25441 cgttgctcaa tccactcact tgtcaacccg ctcaattcaa gaaaatgttg gttatctacc
    25501 cgttcttcag gcacataaaa ccctgtcgca ttaataaaca ttccttagtg tctttgattt
    25561 acttaatctt tattccgttg aatattaaat tcatcacatt gtctctacgt ttaatccgct
    25621 ggctgatatt atcacccatg atcccccgga tatagggcac ctccagccct ttcaaggcat
    25681 gatggagcac gagggcggta atgtccgtgt ccggcatgct gaatataccc tccttcacgc
    25741 catcgtccaa tattcccttt atgatctcca cttcccgaag gtcgaagctc ttgcgtacct
    25801 tctccacccg ccatatatca cggaagaagg tagctcgcaa cgtaccgttc cgaaatacca
    25861 acgcctttac agcgtccaag cggctataga taaacgtcag caacttctcg tccgccggca
    25921 gatccttgct ggccacgtcc accagcatct tatgaagctg gtccagctcc gactccacta
    25981 ccgccaaata gatctcgttc ttgcttttaa agtacgtata aagcgtacgt ctccccttac
    26041 gagatgcctg tgcaatatcg ttcatcgtcg tgttatcaac ccccatgcgg gcaaacaatt
    26101 gtctagccac atccaccaac atgtcacgtg ttttagaaac tgtcatcggc attgtattgc
    26161 acattttgat taaaactgtg cgcaaagtac ttaaaaaaga tcgtatctac caagtatatt
    26221 aaaaaaaact tgcaataaat ttgttttgta agaaaatatc cctacctttg cactcgcaat
    26281 caagaaatga tagcaactat atcgcggagt ggagcagtgg tagctcgttg ggctcataac
    26341 ccaaaggtcg taagttcgag tcttgcctcc gcaactaaga aaagccttcc ggtctgtgac
    26401 cagaaggctt ttcctttttc gtaacccaat ggtttacggg gtgggaatca ttgagttttt
    26461 cccgtaatcc attgacttac gtaccgtaaa ccattcgctt acgcccaaca agtcacatag
    26521 gcttacgtcc ggggcctctt attggtttcc cggacgtagg gcctacagtt cctatctcaa
    26581 ggcaggcaag atatatttcc atatcaagtc gatctcggcc tgcatatcgc cgatattcgc
    26641 cgtcatggcg attaccgcat cttgctcggg caatataata atgtattgtc cattggctcc
    26701 atcggcacga acggcgttat ggcggcaacg ccacatctgg taaccgtagc cttgtaacca
    26761 gtcgctatct ttcggcttca tcttcaagtt ctccggtctc ataccggcgg gcaaagaggc
    26821 tatcttggag gtggtggctt cctctatcca gctttcgggg agcaattgct tatcgttcca
    26881 ttttcccttt tgcaggaaaa actgacccat tttcgctaga tcctcggtct tgagatacaa
    26941 accccaacca ccgcaattga cgccttgggg actctcttcc caagtagcgc cgacgatacc
    27001 cagcggacgg aacagacggg gatagagata attgatcacc ttctcccccg tcaccttctg
    27061 gatgatagcg gaaagcatat acgtgccgag gctgttgtat acgaaatagg ttcccggttt
    27121 atgtaccaac ggcgccgaga ggaagagctt
//
LOCUS       DBMDTB010000052        27120 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_642_length_27120_cov_9.806321, whole genome shotgun sequence.
ACCESSION   DBMDTB010000052 DBMDTB010000000
VERSION     DBMDTB010000052.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 27120)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 27120)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27120
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_642_length_27120_cov_9.806321"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..639
                     /locus_tag="ACZPB4_09655"
     CDS             <1..639
                     /locus_tag="ACZPB4_09655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009128927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxyl transferase domain-containing protein"
                     /protein_id="HIR1098515.1"
                     /translation="YAKNIIVGFARFNGQSVGIVANQPKVMAGCLDSNASRKAGRFVR
                     FCDAFNIPLVTLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKITVTLRKSYGG
                     AYCVMSSKHLRGDMNYAWPTAEIAVMGPSGAVEVIFAKEVAAAEDPKACAAEKEAEYK
                     KAFANPYNAAQYGYIDDVIEPRNTRFRIIRALQQLQTKKLSNPAKKHDNLPL"
     gene            661..1548
                     /locus_tag="ACZPB4_09660"
     CDS             661..1548
                     /locus_tag="ACZPB4_09660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008948 - oxaloacetate decarboxylase
                     activity [Evidence IEA];
                     GO_function: GO:0015081 - sodium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0036376 - sodium ion export across plasma
                     membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OadG family transporter subunit"
                     /protein_id="HIR1098516.1"
                     /translation="MINKKIGVLLLFALLISFGAKAQRATSMRINEVLVINEDNFVDD
                     YGKRHGWIELFNTSAGTVNIAGCYLTDDKNNPMKYPIPKGDVLTQIQPRQHTLFWADG
                     QPGRGTFHVNFVLDPSKENYVALYDADGKTLIDEITIPAGQLADISYGRVIDGEKDWA
                     QLKKVTPSTNNLTLDSNEKIDNFRVNDSLGIGMTITAMAVVFLGLFLLYIIFKQIGKL
                     SIAASKRNVEKAVGSASVTADAGQESGEIFAAIATALYEMSDDNHDIENTVLTIRKVQ
                     RAYSPWSSKLYGLRQTPQK"
     gene            1571..2002
                     /locus_tag="ACZPB4_09665"
     CDS             1571..2002
                     /locus_tag="ACZPB4_09665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin/lipoyl-containing protein"
                     /protein_id="HIR1098517.1"
                     /translation="MKSFKYTINGNVYKVHINSVVDDIAELEVNGTPYQVKMEKPAKK
                     QMVTLKRPAQAPTTASGDPVVSRPAASTTQGAVKTPLPGVILQVKCNVGDTVKRGQTL
                     IILEAMKMENNINADRDGKIIEIKVHKGDSVLEGADLVVIG"
     gene            2007..3167
                     /locus_tag="ACZPB4_09670"
     CDS             2007..3167
                     /locus_tag="ACZPB4_09670"
                     /EC_number="7.2.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium ion-translocating decarboxylase subunit
                     beta"
                     /protein_id="HIR1098518.1"
                     /translation="MQESFLTFLGENLQLFLTYTGVYNATPGHLIMILVGLLFIFLAI
                     KYEFEPMLLIPIGFGILIGNIPFKDAGLQVGIYEQGSVLNILYQGVTSGWYPPLIFLG
                     IGAMTDFSALISNPKLMLIGAAAQFGIFGAYTIALQMGFEPNQAGAIGIIGGADGPTA
                     IFLSSKLAPNLMGAIAVSAYSYMALVPIIQPPFMRLLTTKKERLIRMKPPRAVSSTEK
                     IIFPIVGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLAETARGPLIDTITILLGI
                     TVGASTQATQFLTLNSIKIFGLGALSFVIATCAGVLFVKLFNLILKDGNKINPLIGNA
                     GVSAVPDSARISQVVGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLG"
     gene            complement(3234..3380)
                     /locus_tag="ACZPB4_09675"
     CDS             complement(3234..3380)
                     /locus_tag="ACZPB4_09675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098519.1"
                     /translation="MRKKSVNTLLVFGVVVAIILLMIWLFLGTTLVEDTSTEITPVPI
                     EQTN"
     gene            complement(3449..4165)
                     /gene="tsaB"
                     /locus_tag="ACZPB4_09680"
     CDS             complement(3449..4165)
                     /gene="tsaB"
                     /locus_tag="ACZPB4_09680"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HIR1098520.1"
                     /translation="MSLILNIETSTSVCSVALSEGEEVVFEKASFEGPSHAALLGVYM
                     EEALEAAKSKGIKLDAVAVSSGPGSYTGLRIGVSVAKGLCFGYGIPLIGIHTLDILAS
                     AAIRKNKEEADCLYCAMLDARRMEVYSSIYDSHLNTIRATTADIVDADSYASFLENGK
                     VCFFGDGAAKCETVITSPNACFIDGIYPLAVNMASLSQKAYDDGRFENVAYFEPFYLK
                     EFQATIAKNKVLNEALGKNK"
     gene            4355..5227
                     /locus_tag="ACZPB4_09685"
     CDS             4355..5227
                     /locus_tag="ACZPB4_09685"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011965912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YicC/YloC family endoribonuclease"
                     /protein_id="HIR1098521.1"
                     /translation="MIQSMTGFGKVTAELPSKKVTVEIKALNSKQLDLSTRIPSIYKD
                     KEMELRSLLLQSLERGKVEFNIFIEYIGKDTPTQINLAAVENYYNQIKEIAEKLNISV
                     PNDWFQTLLRMPDAIKSETVEPDESEWEVVLETVKDAIKHLCDFRIQEGAMLQKLFEQ
                     KIANIATLLKEVEKYEGERIEKIKARIMDNLQKIAEKDYDKNRFEQEMIYYIEKLDVN
                     EEKNRLDNHLKYFISTMESGHGQGKKLGFIAQEMGREINTLGSKSNHAEMQKIVVQMK
                     DELEQIKEQVLNVL"
     gene            5242..5808
                     /gene="gmk"
                     /locus_tag="ACZPB4_09690"
     CDS             5242..5808
                     /gene="gmk"
                     /locus_tag="ACZPB4_09690"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004385 - GMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HIR1098522.1"
                     /translation="MAGKLIIFSAPSGSGKSTIINYLLKQDLHLRFSISATSRAPRGT
                     EKNGVEYYFLTPEEFRSRIANGDFLEYEEVYTDKYYGTLKSEVERILNEGDNVIFDVD
                     VVGGCNIKKFYGDRALSVFIQPPCIDDLRKRLEGRGTDSPEVIESRIAKAEYELGFTG
                     QFDKVVVNDDLETAQKDALKIIREFLNK"
     gene            5812..5991
                     /locus_tag="ACZPB4_09695"
     CDS             5812..5991
                     /locus_tag="ACZPB4_09695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098523.1"
                     /translation="MSNIFKNTRFMMGLSIVCGIASLVLGGISLYYKEYIIGGALIFN
                     IFICFINYKGWQKKG"
     gene            6003..6578
                     /gene="nadD"
                     /locus_tag="ACZPB4_09700"
     CDS             6003..6578
                     /gene="nadD"
                     /locus_tag="ACZPB4_09700"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000309 - nicotinamide-nucleotide
                     adenylyltransferase activity [Evidence IEA];
                     GO_function: GO:0004515 - nicotinate-nucleotide
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD+ biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate (nicotinamide) nucleotide
                     adenylyltransferase"
                     /protein_id="HIR1098524.1"
                     /translation="MRLKTGIYSGSFNPIHIGHLALANWLCEFEGLDEVWFVVTPHNP
                     LKKKDDLLDDSLRLEMAQAAIDGYPKFKVCDIEFHLPKPSYSIDTLRALSSNYPDRDF
                     YFIMGADNWLLFPRWKEYEKILQNYKLLIYPRLGFDISIPTIYPNVKKVDAPLMEISS
                     TFIRNAYQTGKDIRFFLPEGVRPYFGSVANQ"
     gene            7210..7353
                     /locus_tag="ACZPB4_09705"
     CDS             7210..7353
                     /locus_tag="ACZPB4_09705"
                     /inference="COORDINATES: protein motif:HMM:TIGR04149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098525.1"
                     /translation="MMKILGGGSAYCHCHNLSSSIEVTSCSECSNKCSNYGGVQNCNT
                     TGG"
     gene            7427..8542
                     /locus_tag="ACZPB4_09710"
     CDS             7427..8542
                     /locus_tag="ACZPB4_09710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-bladed beta-propeller"
                     /protein_id="HIR1098526.1"
                     /translation="MIYLLFLVTLLLISCNPDQAKDNGKDETIEYFIPLSHRVEKDVD
                     EMFEEYRYVPLETRDDALIDVLYNVKNIAIFQEDIYIGSGEQLIVWDKYGKFKRVLSK
                     KGNDPQSYLHFNHFMIWPNGDLSIASPIEIVTYSNSHQFINKKRCENVGYIEAITLLN
                     DSLYIIKCMPTPEQLRYRIINHHTGAIINSYDSIINCNRYISSFTNSFERYEGHIISH
                     GYQSNDILECTLDSSKIRYKINVDNRIPPAGFYTQEGKEGMQLIQEEAEKGYIGHIPD
                     YVESKETILLSFKGKREDLNGIALIDKKDGNARVLENIKFDDNFRWLPKQFFSLDEGW
                     CAMLMYPEDVLKKEEFARRFPGLDEESNPVLFIGKLR"
     gene            8562..10109
                     /locus_tag="ACZPB4_09715"
     CDS             8562..10109
                     /locus_tag="ACZPB4_09715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vitamin K epoxide reductase family protein"
                     /protein_id="HIR1098527.1"
                     /translation="MEHDNLFIQILEILSIKHTEDFTIRYYERHPHKNNLFGLSEMLR
                     YYNIENVAAEIQKTQENLSSLDVPFVAYVDHEFVLVRHVSTEAIIYSWRGKNITLSIP
                     VFLERWSGIVLLFESTDESIEPDYKEHRKEYLRQRIVIACFVSLLLSLIGCALITNRG
                     MEIGIWGLWGVNVIGASFCGILLSREILGSDKYVNKICSLFLKSSDCNGTLDSQASHF
                     LGISWSVFGLGYFLSAILFIALLPQYVIYAETLNIIALPYTAWSVWYQKFRVKQWCAL
                     CLSVQATVWITFLISLFAIGMDFNQWDLFDFTTIGCVYGLVILSLHFTVTLYVKEKQI
                     QRSNNKLSSIKLNASVFKSLLNEQPQYDIDKNTGILLGNRDAKEWITIISNPHCAPCA
                     KLHLQIEKLLKEYKEEICIQIILTSFSKELEPSAMLLTSMYLLNNESDYLRFLSDWYA
                     KGRHKKEDCYKRYRLNPNDKDMLANFQAQNEWVRRNTISSTPTVLTNGYLLPEEYELK
                     DMSYLIN"
     gene            10115..11158
                     /locus_tag="ACZPB4_09720"
     CDS             10115..11158
                     /locus_tag="ACZPB4_09720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098528.1"
                     /translation="MNKLASQIDSLNKHLIGSLHTSYPFGLAHGKMGLLIYLYHLYDY
                     TQEAIYKEKAERLLDDLLENDLSKNAELTVEEGLCGVALGLDYIVKKQFVDGDINDLL
                     SGIDDLLFKKLVFGNMESRYSLSQLIHFLYYIYKRLEIQTNDNERFPFEGLAIKLVNQ
                     LADLIDASFFEESYTFSIYQYHVPILMKTLSYLIQYDFYKDRIQKVLEQLSLYMFSHL
                     PHLHLNRLYLLWGILPLRNCSPDWQRYVNELRKSINLDIIYNREIKGKDIYISNGYAS
                     LYFLLEGLKRDFPEYTIPFNPHLIYDRIISSDAWDALMENEYYYNIHRGLLNGFPGTV
                     LALLNIKQRYLCE"
     gene            11149..11838
                     /locus_tag="ACZPB4_09725"
     CDS             11149..11838
                     /locus_tag="ACZPB4_09725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactosyltransferase-related protein"
                     /protein_id="HIR1098529.1"
                     /translation="MRIDLTDTTFIIPVRIDSMIRLENLLMSVDSIVRYFRTRILIME
                     ASSYQNEIIPSLIKDDTVKYTFLVDKDPVFYKTKYLNILAKQVDTPLVCIWDADVILD
                     HLQILDAVKQLRTRTSDVAYPYDGNFLDTSDILREHYWLHRDLDFLKKHQAKMNSLYT
                     VEGVIGAVGGAVFAQTEKYLQAGMENEDFYGWGLEDGERHYRWLSFGYRIYRSEGCLF
                     HLSHPRDQNGM"
     gene            12041..13771
                     /gene="lysS"
                     /locus_tag="ACZPB4_09730"
     CDS             12041..13771
                     /gene="lysS"
                     /locus_tag="ACZPB4_09730"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HIR1098530.1"
                     /translation="MNLLELSEQEIIRRNSMEQLRQMGIEPYPAAEYVTNAFSKEIKE
                     TFKDDAEPRPVRIAGRIMSRRIMGKASFMELQDSEGRIQVYISRDDICPDENKDTYNV
                     VFKKLLDIGDFVGIKGFVFRTQMGEISVHAQELTVLSKSLRPLPVVKYKDGVAYDGFN
                     DPELRYRQRYVDLVVNEGVKDIFMKRAAIIKTMRTALDEAGYTEVETPILQSIAGGAS
                     ARPFITHHNSLDIDLYLRIATELYLKRLIVGGFEGVYEIGKNFRNEGMDRTHNPEFTC
                     MELYVQYKDYNWMMSFTEKLLERICIAVNGTSESTIDGKTISFKAPFRRLPILEAIKE
                     KTGYDLEGKTEDEIRAICKELKMEIDDTMGKGKLIDEIFGEFCEGTFIQPTFIIDYPV
                     EMSPLTKMHRSKPGLTERFELMVNGKELANAYSELNDPIDQEERFKEQLRLSEKGDDE
                     AMFIDQDFLRALQFGMPPTSGIGIGIDRLVMLMTGQTTIQEVLLFPQMRPEKTVKKDN
                     ADKYVALGISEEWVPALQKAGYLTVDTLKEANANKLRQALCELNKKYKLELQNPTIQE
                     IEAWIANVGE"
     gene            13784..14779
                     /locus_tag="ACZPB4_09735"
     CDS             13784..14779
                     /locus_tag="ACZPB4_09735"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008759775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0046167 - glycerol-3-phosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HIR1098531.1"
                     /translation="MDLPGKIAIMGGGSWATALAKIVLSTQDSINWYMRRPDRIEEFK
                     QLGHNPCYLTAVKFDTNKINFYSNINQAIKDSDTLIFATPSPFLKQHLKKVKTSLKDK
                     FIISAIKGIVPDENMLITDYFAEYYKVPTENIAVIGGPCHAEEIALERLSYITLACSD
                     IEKVRTISPVFKNQYLKNSFCKDVTGIEYAAVLKNVYAIAAGICHGMKYGDNFQAVFI
                     SNAIEEMRNFVDAVHGLERDITDSVYLGDLLVTAYSRFSRNRTFGTMIGKGYSVKTAQ
                     LEMEMIAEGYYGTKCMREINEKYKVNMPILDAVYDILYEKKSPTTVIRQLTETFK"
     gene            14788..16131
                     /locus_tag="ACZPB4_09740"
     CDS             14788..16131
                     /locus_tag="ACZPB4_09740"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HIR1098532.1"
                     /translation="MKNISLNIDKALGTVSKEQVYAQEAKAMECIATLHNGNGAGNDF
                     LGWLHLPSSITDTELADIENTANVLRSKCEVVVAIGIGGSYLGTKAVVEALNNSFDWL
                     QNGRKNPVMLYAGHNIGEDYLYELSEVLKGKQFGIINISKSGTTTEPALAFRILKKQL
                     EDAVGKEEAKHRIVAITDAKRGALRTLADQEGYKTFIIPDNVGGRFSVLTPVGLLPIA
                     VAGISIRNLVAGAVSMEKATDASVPFADNMAAIYAATRNELYKNGKKIEILANFHPKL
                     HYIAEWWKQLYGESEGKDGKGIFPASVDLTTDLHSMGQWIQDGERTIFETVISVEATA
                     HSVLVPTDEADLDGLNFLAGKHVDEVNKMAELGTQLAHVDGGVPNIKVNMPEVSAFYI
                     GQLFYFFEKACGISGYMLGVNPFNQPGVEAYKKNMFALLNKPGYEKESEAIKARL"
     gene            complement(16202..16477)
                     /locus_tag="ACZPB4_09745"
     CDS             complement(16202..16477)
                     /locus_tag="ACZPB4_09745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030527 - structural constituent of
                     chromatin [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HIR1098533.1"
                     /translation="MNRGELVQSLVEETGLPKNVVRAVVNALPTVVAKGIREGESISM
                     KGFGSFVPWQQSERLARNPKTGEEVMITPRVSVKFKAGSDLLKELNE"
     gene            17064..17819
                     /locus_tag="ACZPB4_09750"
     CDS             17064..17819
                     /locus_tag="ACZPB4_09750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HIR1098534.1"
                     /translation="MIQEAIIRYLRKHRQESLSPKAVLFDMDGVLYDSMRFHARAWHE
                     VATLHQLTSRPEDFYMFEGRTGESTINELYQRTFQRDATAEEKQTIYKEKADLFNTYN
                     DGAPMTGAAEVLKEVEASGLQRLVVTGSGQHSLIDKLNHTYPGHFNREKMVTAFDVKY
                     GKPHPEPYLMGLQKAHVKPNEAFVVENAPMGVEAAVAANIFTIAVNTGPLPDQVLLDA
                     GADLLYPDMENLAKDWKQIIELAKSTRLNEYSK"
     gene            complement(17884..18786)
                     /locus_tag="ACZPB4_09755"
     CDS             complement(17884..18786)
                     /locus_tag="ACZPB4_09755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HIR1098535.1"
                     /translation="MQNRRNFLKQASLMLAGGLVAPQLLSSCGGKSGQAAATASESSK
                     YIGLQLYSLRDLVKEEGIQKVLETAAKMGYKNLETASYDNGKIYGLAPAEFKKMVNDL
                     GMKCTSAHLGQAFTKEKEAEVMSWWDQAIDAHNELGVKYMVQPWMPVNDKTTLDDLKM
                     YCDYFNTVGYKTAAASIAFGYHNHDFEFRKIDDQLIYDFLLDNVSPNHVFFEMDVYWV
                     MMGGGDPVAYLKNRPSQFKAIHIKDEKEIGASGKMNFKPIFDQMYANNVKDWYVEVEQ
                     YTNNDPVASVQQSYDFLNKADYVK"
     gene            18942..20330
                     /locus_tag="ACZPB4_09760"
     CDS             18942..20330
                     /locus_tag="ACZPB4_09760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-alpha-glucoside-1,2-lyase-like
                     domain-containing protein"
                     /protein_id="HIR1098536.1"
                     /translation="MKKLSILAMGLLFVLTTACSVSGSGTLFDGKDSNKWKMTGDVSV
                     QDDIMTLKGTDALAVLKNGKYKNFDLTLDLRTTPGGKGAVWFHTDPTLKKGYRIAINN
                     DRADKVWWKMTGSLVSVRNLTKSFVKEDQWFKMDIRVAGQEIDVNINGEPVVEYIQPT
                     APYRTDANAYALLSEGTFAIESDGSGEIQIKNITVNVIDESTIDINAQLAEANDEQND
                     EIIKLHQSDFPVLDYHVHLKGGLTKEVAAKQSRKTGINYTIAPNCGIGFPITNDQQVM
                     DYLNEMRSQPFILGMQAEGREWITTFSPETLKEFDYVFTDALTFKDNKGRRTRLWIPE
                     ETWIENEEQYMDMIVDRICSVLEEPVDIYVNPCFLPSPMDKRFDEFWTEARMNRFVEA
                     LAKSGKALEINELYNIPNKAIIMKAKAAGVKFTFGSNNVTPNVSDLSYSIRMMKECGL
                     TAEDMYKPKVKI"
     gene            complement(20408..21664)
                     /locus_tag="ACZPB4_09765"
     CDS             complement(20408..21664)
                     /locus_tag="ACZPB4_09765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011965909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1098537.1"
                     /translation="MKREHRLRYIIKEGLLDTFYIWKDELRNVFKDAGVMIFFFLVPF
                     VYPLLYSFIYNNEVVHEAKMVVVDQSDSYLSREFTRRVNATPDVEVVGVCPDMAEAKK
                     MLDEKKAYGILLFPPDYSKDLHEGRQTTVSLYCDMSALLFYKAFLLAATEVSLDMGKE
                     LRMHNNPSSTDKMDQITVDPIPYESVALFNSQNGFASFLVPAILILVLQQTLILGIGM
                     LGGTAREKNRFHSLVPICRHFNGTLRIVFGKSLTYLLLYVVVCIWVLAIVPKLFSLPQ
                     VGEPLTILLFLLPYLFACIFMSMTLSGFMTSRESPMLVFVFTSVILLFISGVSWPEAA
                     IPPFWKVVGYLFPSTPGIQGFIRINTAGASLHEVAHEYRVLWIQAGVYFILSCIIYRY
                     QIIRSRKMIIKQYRYMKMRRMLRERE"
     gene            complement(21677..22855)
                     /locus_tag="ACZPB4_09770"
     CDS             complement(21677..22855)
                     /locus_tag="ACZPB4_09770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1098538.1"
                     /translation="MTYKESLHRIWLITKREVHRLVAQPIYFFCMLIAPAICVIFFVS
                     LMHEGLPTDLPIAVVDMDNSATSRNLIRQLDAFEQTEVYMKTMSFTEARQEMQKGNVY
                     GIFYIPSGFAVDATSGKQPRLSFYTNGTYLIAASLLFRDMKTMSVLAGAAVGLQTGQA
                     KGYTEAQIMGQLQPIVIDTHPIGNPWLNYSVYLNNTVLPGIIQLMVFLVTVFSIGTEI
                     KYSTSRKWLDMGGNSIAVSLLGKLLPQTAIFTVVGFMYCAVLYGINSFPLNSGWFPML
                     LAMFLLIISSQAVGVFMIGVLPTPRLGLSFASLFGMISFSIVGFSFPVQGMDPTLQAL
                     TRLFPLRHYFLIYVDQALNGRALFYTLGEYAWLLGFLILPFLIGRNLKRALLDFKYLP
                     "
     gene            complement(22852..23865)
                     /locus_tag="ACZPB4_09775"
     CDS             complement(22852..23865)
                     /locus_tag="ACZPB4_09775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HIR1098539.1"
                     /translation="MNENKKFSISNMMLAFITVLVVIGLVALAGFFLLTPPDDIIMGQ
                     AEATQVRISGKVPGRIASYRFGEGDQVKAGDTLVFLDTPEVMAKLKQAEAARAAAEAQ
                     NAKAIKGAREQEITAAYEMWQKAQAGLTIAKKSFDRIQNLYEKGVMSAQKRDEVEANY
                     NAMVATEKAARSQYEMAKEGAREEDKAAAAAMVQRAEGAIAEVESYVGESALVAPIDG
                     EVSERFPEVGELVGTGAPIMNISDLNDVWVTFSIREDLLKDIKIGSEVNAFIPALGDL
                     PVKLKVYYMKDMGSYAAWKATKTNGQYDSKTFEVRARPLEKVADLRPGMSVILKKKGK
                     EIV"
     gene            complement(23896..25281)
                     /locus_tag="ACZPB4_09780"
     CDS             complement(23896..25281)
                     /locus_tag="ACZPB4_09780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HIR1098540.1"
                     /translation="MKRTILLLTFVVTVSCMHAQRMLTLEECRNLAIQNNKELQISGE
                     KIKMADNEKKAAFTKYFPQLSANGAYMWNQKDINLLDMGALSSSLSSSLGGLAQLPMI
                     QHLMSGVNDMQHLDVQNIWVGNVSLVQPVFMGGKIVNYNQITKFAKQLAESMNNLQLQ
                     DLIYKTDETYWQVISLVNKKKLADAYVDLLRKMDSDVTAMIYEGVATEADGLSVKVKL
                     NEAEMAQTKVENGLALTRMLLAQICGLSLEEDLSLADEKLDNFPVETTQASADLNEAF
                     MNRNELRSLDLATKIYKRKERIALAEMLPNVALAANYFVTNPNVFNGFKNDFAGMFNV
                     GVMVKVPLSGWWEGTYRRNSAKAETRIKTLEWQDAREKIELQVNQSVYKVNEAGKKLI
                     ASSRNMENAEENLRRANFGFEEGVIPALNLMEAQTAWVSARSSLIDAQIEVKLTEVYL
                     SKALGKLSANE"
     gene            complement(25393..25986)
                     /locus_tag="ACZPB4_09785"
     CDS             complement(25393..25986)
                     /locus_tag="ACZPB4_09785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HIR1098541.1"
                     /translation="MKLSPDFEKFLSFIPEILSRDESFLKDLESCTRGVTIRKGDYLI
                     RTGELCQDAYFINKGLFINQYINENGNECVTGFSSDSMYPFVSTIGYFTQVPSEFEVK
                     AIEDGELLCFSRTDIERLSLGYPAFATCYQNVMLMIISKLYSMFAVRQTCKAEEFLKY
                     LYTNHQWIVSRVPDKYIAQYMGVSDSWYCKLKKRILY"
     gene            complement(25989..26894)
                     /locus_tag="ACZPB4_09790"
     CDS             complement(25989..26894)
                     /locus_tag="ACZPB4_09790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098542.1"
                     /translation="MDTEKKENKEVNKLSLLIVAVIVLVLIIAGAGYYIYHQKQQMTD
                     LVETFDLEKESLEDEYNELSLQYEGYKFSVGNDSLVALLSTEQAKVQRLLEELRTVKA
                     TNAKEIARLKKELDTLRKIMRNYVVQIDSLNRENEQLKVEKKEAVQKYQRATSQAATL
                     KKEKEKLTERVTLASRLDATDINVTPVNSRGKLAKRIKKMQQFVVTFKIAKNITAPVG
                     EKMVYVRIMKPDDDILVKSRADVFAFEGKEINYSMKKMIEYEGEEVAVTMYWNIEEFL
                     SPGTYRVDIFSDGNLIGQKRFTLDD"
BASE COUNT         8168 a         6006 c         5596 g         7350 t
ORIGIN      
        1 tacgctaaga atatcatcgt aggtttcgct cgtttcaacg gacaatctgt cggtatcgta
       61 gccaaccagc cgaaggttat ggcaggatgc ttggatagca acgcatctcg taaagcaggt
      121 cgcttcgttc gtttctgcga cgctttcaat attcctttgg taacattggt tgacgttccg
      181 ggattccttc cgggtacagg tcaggaatac aacggtgtaa tccttcatgg cgctaaattg
      241 ctttacgctt atggtgaggc taccgttcct aagattaccg ttacattgcg taagtcttac
      301 ggtggagctt attgcgtgat gagttctaaa catttacgtg gtgatatgaa ttacgcatgg
      361 ccgacagccg agatcgccgt tatgggcccg agcggtgccg tagaggttat cttcgccaag
      421 gaagtagcag ccgctgaaga tccgaaagca tgcgcagcag agaaagaagc tgaatataag
      481 aaagcattcg ctaatcctta taacgcagct caatacggtt atatcgacga tgttatcgaa
      541 ccgcgtaaca ctcgtttccg tataattcgt gctttgcagc aattgcagac taagaagcta
      601 agcaatcctg ctaagaaaca tgataacctg cctctataat ccgtaaaaca ggagatgaat
      661 atgataaata agaaaatagg ggtattgcta ttgttcgctt tgctcatttc attcggggca
      721 aaggcacagc gcgcaacctc catgcgaatt aatgaagtat tggttatcaa cgaggataac
      781 ttcgttgatg actatggcaa acgtcatggc tggattgagt tgttcaacac ttcggccgga
      841 acggtaaata tcgcgggatg ctatttgaca gacgacaaaa acaatcccat gaaatatccg
      901 atcccgaagg gagacgtatt aactcagatc caaccccgcc agcacacact attttgggct
      961 gacggacagc cgggcagagg tacattccac gttaacttcg tattagatcc ctctaaggag
     1021 aattatgttg ccttatatga cgccgacggt aagaccttga tcgatgagat cacaattccg
     1081 gcaggccaat tagcagacat tagctacggt agagtgattg atggcgaaaa agactgggca
     1141 cagttaaaga aagtcactcc cagtacgaac aacttgacgt tggactccaa tgagaaaatc
     1201 gataacttca gggttaatga ctctttaggt atcggtatga ctatcacggc tatggctgtt
     1261 gtattcttag gtctgttctt gttgtacatc atctttaagc agattggtaa attatctatc
     1321 gccgctagca aacgtaacgt agagaaggcc gtaggttctg cttcagttac cgcagacgca
     1381 ggacaagaat ctggagagat attcgccgcc atcgctaccg ctctatacga aatgagcgat
     1441 gataatcacg atatcgagaa cacggttctc actatacgta aggtacaacg agcttattct
     1501 ccttggagtt caaaactcta tggcttacgt caaactcctc aaaagtaatt atctaaaaac
     1561 gaactaaaga atgaaaagtt ttaaatatac cattaacggt aacgtatata aagtacacat
     1621 caattctgta gtggatgata tcgcagaact tgaagtaaac ggaactccct accaagttaa
     1681 gatggagaaa ccggcaaaga aacaaatggt tacattgaaa cgcccagctc aagccccgac
     1741 tacggcaagt ggagaccctg ttgtttcccg tccggcggct tctacgacac aaggggctgt
     1801 taagactccg ctaccaggtg ttatcttgca ggttaagtgc aacgtaggtg ataccgtgaa
     1861 gagaggtcaa accttgatta tccttgaggc tatgaagatg gagaacaaca tcaacgcaga
     1921 ccgtgacggt aagattatag aaattaaagt acacaaggga gactctgtgc tagaaggtgc
     1981 tgatctcgta gtaatcggat aagactatgc aagagagctt tttaacattc ttaggtgaga
     2041 acttacaact gttccttacc tatacaggtg tatacaacgc tactccggga catctcatca
     2101 tgattctggt aggtctgttg tttatattcc tggcgattaa atatgagttt gaaccgatgc
     2161 ttttgatccc tatcggattt ggtatcttga tcggtaatat ccctttcaag gacgcaggtc
     2221 ttcaggtagg tatttatgag caagggtctg tactgaacat cctctatcag ggtgtgacct
     2281 ctggatggta tccgccattg atcttcctcg gtatcggggc catgaccgac ttctccgcat
     2341 tgatctccaa tcctaagttg atgttgatcg gtgcagcggc tcagttcggt atctttggtg
     2401 cttatacgat tgctcttcaa atgggatttg agccgaacca agcaggtgct atcggtatta
     2461 tcggtggtgc tgacggtccg acggctatct tcctttcttc taagttagcg ccaaacttaa
     2521 tgggtgcgat cgcggtatcc gcttactcat acatggcgtt ggttcctatt atccaaccgc
     2581 cgttcatgag attgcttacg actaagaaag agcgtttgat ccgtatgaaa ccgccgagag
     2641 ccgtttcttc cacggaaaaa attatcttcc cgatcgttgg tttgttgctt acttgcttct
     2701 tggttccgtc cggtttacca ttgttaggta tgctattctt cggaaactta ttgaaagaaa
     2761 gtggcgtgac tcgtcgtttg gcagagactg ctcgtggtcc gctgatcgat acaatcacga
     2821 tcttattggg tatcacggta ggtgcttcta cccaagctac acagttcttg acattgaact
     2881 ctatcaagat cttcggtcta ggtgcgttat cattcgtgat cgctacttgc gccggtgtat
     2941 tgttcgttaa gttattcaat ttaatattga aagatggcaa taagatcaat ccgcttatcg
     3001 gtaacgccgg tgtatccgcc gttcctgact cagctcgtat ctcacaagtt gtaggtttgg
     3061 aatatgaccc gaccaactac ttgttgatgc acgctatggg tccgaacgta gcaggtgtaa
     3121 tcggttccgc tgtagctgcc ggtatcttgc taggattcct tggttaataa aacaactatc
     3181 tatattaaaa aaggcgaggt ccgaaaggat cccgcctttt tatgttattg ttctcagtta
     3241 gtttgctcta taggaaccgg agtaatctcc gtactcgtat cctccaccaa cgttgtcccg
     3301 aggaacaacc agatcatcaa aaggattata gcgacaacca caccaaatac caatagcgta
     3361 ttcacacttt tctttctcat gtctttaact gatttattca ttttagaata aacagccgga
     3421 acatgaattt ggttgtgtac ccttactctt atttgttttt ccctaacgcc tcgttcagca
     3481 ctttgttctt agcgatcgtt gcttggaatt ctttcaaata gaaaggctca aaataagcca
     3541 cattctcaaa acggccatca tcatatgctt tctgcgacaa ggatgccata tttacagcta
     3601 atggatagat accatctata aaacaggcgt tcggagaagt gattactgtc tcacatttag
     3661 cggcaccgtc tccaaagaaa caaaccttac cgttctctaa aaaagaagca tacgaatcag
     3721 catctacgat atcagcagtc gtggcacgta tcgtgttgag atgggaatca taaatcgaag
     3781 agtagacttc catacgacgg gcatccaaca tagcgcaata caagcaatcg gcctcctcct
     3841 tatttttccg gatagcggca gacgctaaaa tatccagcgt atgaataccg atcaaaggaa
     3901 taccataccc aaagcataat cctttagcca cagacacccc gatgcgtaac cccgtataag
     3961 atccgggtcc gctacttacc gccacggcat ccagttttat ccctttcgac tttgcggctt
     4021 ctaatgcctc ttccatataa acgcccaata acgccgcatg agacggcccc tcgaaggaag
     4081 ccttctcaaa gaccacctcc tccccttccg acagggctac tgaacatacg gaagtggatg
     4141 tctcgatatt taagatcaat gacataataa ttaactatta acaattgata attgaacgaa
     4201 caaacaatct caaaccttca atctgattag gctacgaagg tatacaaaaa ttcattatac
     4261 tatcaaggca gccctatgag aaacatctat ttatgagaaa ataaacatca aatctaaaag
     4321 gaaaccacta tctttgcgca aacttttgag aaaaatgata caatcaatga ctggattcgg
     4381 taaggttact gccgagctcc cttcaaaaaa agtaaccgta gagataaagg ctttaaacag
     4441 taagcaattg gatttgtcca cccgtatccc ttccatatac aaagataagg aaatggagct
     4501 tcggagcctg ttacttcaat ctttggagcg gggaaaagtt gagttcaata tctttataga
     4561 atatataggc aaagatactc ctacacagat caatcttgcc gccgtagaga attattacaa
     4621 ccaaatcaag gagatcgcag agaaattaaa tatcagcgtt ccgaacgatt ggttccagac
     4681 cttgctccgg atgccggacg caatcaagtc cgagaccgta gaaccggacg aatccgaatg
     4741 ggaggtggtt ttagaaacgg taaaggacgc tatcaagcac ctgtgtgatt tccgtatcca
     4801 agaaggagcc atgcttcaaa agcttttcga gcaaaagata gccaatatcg ccactctgtt
     4861 gaaagaagtg gagaaatacg agggggaacg tatcgagaag atcaaggctc gtatcatgga
     4921 taacctgcaa aagatagccg agaaggacta cgacaagaat cgtttcgagc aggagatgat
     4981 ctattacata gagaagctgg atgtcaacga ggaaaagaac cgtctggaca accacttgaa
     5041 atattttatc tcaaccatgg aatccggtca cggccaaggc aagaagctcg gttttatcgc
     5101 tcaggaaatg gggcgtgaga tcaatacgct cggatcaaag agcaaccacg ccgagatgca
     5161 gaagatcgtg gtccagatga aagacgagtt ggaacaaatc aaggaacagg tactaaacgt
     5221 attataataa gattaacgag aatggctggc aaattaatta tcttctccgc accctcgggt
     5281 tccggaaaat caaccattat taattatctt ttgaaacaag atttacacct tcgtttctcc
     5341 atctcggcta ccagccgggc tccgcgggga accgagaaga atggtgtgga atattatttc
     5401 cttacgccgg aagagttccg cagtcgtatc gctaatggag acttcttgga atatgaggag
     5461 gtgtataccg ataaatatta cggtacgtta aagagcgagg tagagcgtat cttgaatgaa
     5521 ggggacaacg tgattttcga tgtggatgtg gtaggcggat gcaatatcaa gaaattctat
     5581 ggagaccgtg ccctgtctgt ctttatccaa cctccttgca tcgatgacct acggaagcga
     5641 ttggaaggac ggggaacaga cagcccggaa gttatcgaaa gccgtatcgc caaggctgag
     5701 tatgaattag ggttcacggg acagtttgat aaggttgtcg taaacgatga tctggagact
     5761 gcccaaaaag acgcattgaa gatcattcgt gagttcttaa acaaatagtc tatgtctaat
     5821 atattcaaga atacccgttt tatgatgggg ctttctatcg tttgtgggat agcgagcctc
     5881 gtattaggtg gtatcagcct gtattataag gagtatatca tcgggggtgc cctgatattt
     5941 aatatattca tttgttttat caactataag ggttggcaaa agaaggggta agtataaatc
     6001 ggatgagact caagaccggc atctacagtg gatcgttcaa tcccattcac ataggccatc
     6061 tcgccttggc gaactggcta tgtgagttcg agggactgga tgaggtgtgg ttcgtggtca
     6121 cgcctcataa tccgctgaag aaaaaggatg acttgctaga tgactcacta cggttggaaa
     6181 tggcccaagc cgccattgac ggatacccga aattcaaggt ctgcgatatt gagttccacc
     6241 tgccgaaacc ttcttattcc attgatacct tgcgagcctt atccagcaac tatccggata
     6301 gggactttta ttttatcatg ggagccgata actggctgct ttttccccga tggaaagaat
     6361 atgaaaaaat actccaaaac tacaaactgc tgatttatcc ccgcctagga ttcgatatct
     6421 cgatcccaac catttatccg aacgtgaaaa aggtagacgc tcccttgatg gaaatctcct
     6481 ccacatttat ccgtaacgct taccaaaccg gcaaggatat ccgtttcttc ctgccggaag
     6541 gagtgcggcc ttatttcggg tcagtagcaa atcagtgaca tacctgcgat agaagatata
     6601 cttacttggg ctatgaagta tatatcctat gccacttgaa gtatatattc ttcgagaagg
     6661 gaagttatac cgtgattatt tacagctttg ccatcttagg gcaatctgcc aaaattccca
     6721 ttaaaacatg ttttacagca cagccgttaa agatgatccc cgtaacatca aaacaggctc
     6781 acccgataat ctttttggag tatccaaata tataatttga gccttgtcaa gtgattagtt
     6841 attcatttgg gaggctttgt acctatagct tacgctatta cataaaacac tattacataa
     6901 caaattacat caatacaata agtcatttct cgaacaaatt aaacgtggga cagaacaatc
     6961 gaattcgcat agctaactta tatgcatatc tccactaatt ttctactgta gcaatagaaa
     7021 gacaatatac attaaacaac aataaaaaag acataatata ccccatgttt gatatttttt
     7081 aattttcttt gtaatatcaa agtattacac atctattaac tttttaaatc tttcaaatta
     7141 tggacaaact caaaaaaact gacaaaagtc gtactaaacc aacaaagtaa agttcttcca
     7201 aaagaacaaa tgatgaaaat cttaggggga ggaagtgcgt attgtcattg tcataatctt
     7261 tcttcctcaa ttgaagtaac aagctgctct gaatgcagta ataaatgctc aaattatggc
     7321 ggcgtacaaa actgtaacac tacaggaggt tagcaacaaa agaaagggct ggttttagct
     7381 ggtgatatct gctaaaacca gcttttttct taaaacaaaa atgaccatga tctatcttct
     7441 atttttagtc actcttttgc ttatcagttg taatccggat caagccaagg ataatggcaa
     7501 ggacgaaaca atcgagtatt ttattccact ctcacatcgg gtagaaaaag acgtggatga
     7561 aatgtttgag gaatatcggt atgtcccctt ggaaacaagg gatgacgcat tgatagatgt
     7621 gctttacaat gttaaaaaca tcgctatctt tcaagaggat atttacatag gctccggaga
     7681 gcaattaatc gtttgggata aatatggaaa attcaaacga gtcttatcca aaaagggaaa
     7741 tgatccgcaa tcatacctcc actttaacca tttcatgata tggcccaatg gagatctatc
     7801 gatcgcttct cccattgaaa tcgtaaccta ttcaaattca caccaattca tcaacaaaaa
     7861 gcgttgcgag aatgtcggct atatagaggc gatcactctt ttgaacgata gtctatacat
     7921 cataaaatgt atgcctaccc ccgaacagct acgataccgt atcatcaacc atcatacggg
     7981 agccattata aactcgtatg attccatcat caactgcaat cgatatatca gttcattcac
     8041 aaactcattt gaacggtatg aaggacatat tatctctcat ggttatcaaa gcaacgacat
     8101 ccttgaatgc actttggata gttcaaaaat acgatacaaa ataaacgtag ataacaggat
     8161 accgcccgcc ggcttttaca cgcaagaggg aaaagaaggc atgcaactca tacaggaaga
     8221 agcggagaaa ggatacatcg gccatatccc ggactacgtg gagtccaagg aaacgatatt
     8281 gctctccttt aaggggaaaa gagaagacct aaacggaata gccttaatcg acaaaaaaga
     8341 cggaaacgca agagttttag agaacatcaa gttcgatgac aacttccggt ggttgcccaa
     8401 acagttcttc tcgttagatg agggctggtg cgccatgctg atgtatccgg aagacgtttt
     8461 gaagaaggaa gagttcgcaa ggcgtttccc cggactggac gaggagagta acccggtgtt
     8521 gttcattggt aaactaaggt aatcattaaa gacctaaagc aatggaacat gacaatctat
     8581 tcatccaaat tttagaaatc ttatcgataa agcacacgga agattttacc ataagatact
     8641 acgagaggca tccacacaaa aacaatctgt ttggactgtc cgagatgcta cgttattata
     8701 atatagagaa tgtagcggcc gaaattcaaa aaacacaaga aaacttatcc tcattggatg
     8761 taccctttgt ggcttacgta gatcatgagt ttgtattggt gcgacatgtt tctaccgagg
     8821 caatcatcta ttcatggcga ggtaaaaaca tcacattatc tatcccggta ttcttggaac
     8881 gatggtcagg aatcgtcctt cttttcgaat ccaccgatga atctattgaa ccggattata
     8941 aagagcatag aaaggaatac ttacgacagc ggatagtaat cgcatgtttc gtttcattac
     9001 ttctatcatt aatagggtgt gcccttatca ccaacagagg aatggagata ggaatctggg
     9061 ggttatgggg tgttaatgtg atcggagcat ctttctgcgg tatcctgctt tctcgagaga
     9121 tcttaggctc ggataaatat gtcaacaaaa tttgttccct gtttttgaaa tccagtgatt
     9181 gcaacgggac attggattcc caagcatctc atttcttggg gatcagttgg agtgtcttcg
     9241 gcttaggata ttttctttcc gcaatattgt ttatcgcctt gttgccccaa tatgttatat
     9301 atgcagagac tctgaatata atcgcattac cttatacagc gtggagcgta tggtaccaaa
     9361 aatttagggt aaaacaatgg tgcgctttat gtttatctgt acaagctacc gtatggatca
     9421 cctttcttat ctctctattc gcgataggca tggatttcaa tcaatgggat ttatttgatt
     9481 tcactaccat tggatgcgtg tatgggctcg tcattctatc gctccatttt actgttacat
     9541 tatacgtaaa agaaaagcaa atccaacgaa gcaacaataa acttagcagc ataaaactga
     9601 atgcctctgt atttaagagc ttattaaacg aacagcctca atatgacatt gacaaaaata
     9661 caggaatatt attgggcaat agggatgcca aagagtggat taccattatc tctaatccac
     9721 attgtgctcc ttgcgcaaaa ttacatctcc aaatagaaaa gttactcaaa gaatataaag
     9781 aagagatttg catacaaatc atcttgacct cttttagcaa ggaattagaa cctagcgcca
     9841 tgctactgac ctccatgtat ctactaaata atgaatcgga ttatttacga ttcctatctg
     9901 actggtatgc aaaagggcgt cataaaaaag aggattgcta taaaagatac agattaaatc
     9961 ctaatgacaa agatatgtta gccaattttc aagcacaaaa cgaatgggtt aggcgcaata
    10021 caataagttc cactccaaca gttttgacaa atggttattt attgccggaa gaatatgagt
    10081 taaaggatat gtcgtattta ataaattaag tactatgaat aaattagcat cacaaataga
    10141 ttcgctaaat aagcatttga taggctcatt acatacaagc taccctttcg ggttggctca
    10201 tggcaaaatg ggattactca tctatttata ccatttgtat gattatacgc aagaagctat
    10261 ttataaagag aaggctgagc gattgctgga cgatctcttg gaaaacgatc tctctaaaaa
    10321 cgcagaactc accgtggagg aaggtttatg cggagttgcg ttaggattgg attatattgt
    10381 aaaaaagcaa tttgtagacg gtgatattaa tgatttgcta agtggtatcg atgatttgct
    10441 attcaagaag ctggttttcg gaaatatgga atctaggtat tccctgtctc aactcatcca
    10501 tttcttatat tacatttata aaaggctgga aatccagaca aacgataatg agcgtttccc
    10561 tttcgagggc ttagcaatca agttagttaa tcaattggcc gatttgatag acgcctcctt
    10621 tttcgaggaa tcctatacgt tttccattta ccaatatcac gtaccgatat tgatgaaaac
    10681 cctgtcctat cttatacaat atgattttta caaggatcgg atacaaaagg ttttggaaca
    10741 actatctctg tatatgttct cccatttgcc tcatctgcat ttgaaccgac tatatctgtt
    10801 atggggcata ctacctttac ggaattgttc gccggattgg caaagatatg tgaacgaact
    10861 aagaaaatca atcaatctag acataatata taatagagag atcaaaggca aggatatcta
    10921 tatcagtaat ggatacgctt ctctatattt cttgttggag ggattaaaaa gggacttccc
    10981 cgaatacacc atccctttca atccgcacct aatttacgat cggatcatct cgtctgacgc
    11041 ttgggatgcc ctaatggaga acgaatacta ctataatata cacagaggat tgctgaatgg
    11101 tttccccggt acggtgttgg cattgttaaa cattaagcaa agatatttat gcgaatagac
    11161 ttgacagata caacatttat tattcctgta cggatcgatt ccatgatccg tttggagaac
    11221 ctgttgatgt ccgtggactc aatagtacgt tatttccgga cacgcatctt aattatggag
    11281 gcctcatcat accaaaatga gattatcccc tcgttaataa aagatgatac ggtgaagtac
    11341 actttcctcg tggataaaga tcctgtattc tacaagacca aatacttgaa tatcctcgca
    11401 aagcaggttg atactccact tgtttgtatt tgggacgcag atgtgatact ggaccacctt
    11461 caaatattgg atgcggtgaa acagcttaga actaggactt ctgatgtcgc ttatccatat
    11521 gatggtaatt ttttagatac gtcagatata ttgagggaac attattggct ccatcgtgac
    11581 ttagatttcc taaaaaaaca tcaagcaaaa atgaactctt tgtacacagt agagggagtg
    11641 ataggcgcag tcgggggagc ggtcttcgcc caaacggaaa aatacctgca agcgggtatg
    11701 gagaatgagg atttctatgg ctggggcttg gaggacggag aaagacatta ccgttggttg
    11761 agttttggct accggattta tcggagtgag ggctgtttat tccatttgtc tcatccccgg
    11821 gatcaaaacg ggatgtaaag ataaaattat tgggtcttaa gttcattggc ctacaaacct
    11881 aagatacttc accaaggatc ctaagatact ttaccgatga acctaagata ctttatccat
    11941 gaactaacaa gatcggtgac ctcaaccttt taccacataa gtcagcataa atcagaaata
    12001 ttttgtactt ttgcgccgta ttatacaaaa taatagcata atgaatctat tagaactgag
    12061 tgaacaggaa ataataagac gtaatagcat ggagcagttg cgtcagatgg ggatagagcc
    12121 ttatcccgca gctgagtatg taacgaacgc attttccaaa gagataaaag agacattcaa
    12181 agatgacgct gagccacgcc cggtacgtat cgccggccgt atcatgagcc gtcgtatcat
    12241 gggaaaagcc tctttcatgg agttgcagga ttccgagggc agaatacagg tctatatctc
    12301 tcgtgacgat atttgtccgg acgagaataa agacacatac aatgtcgttt tcaagaaatt
    12361 actggatatc ggtgatttcg tcgggatcaa gggattcgtt ttccgtactc agatgggaga
    12421 gatttccgtt catgcgcaag aattgacagt tctgtctaaa tcacttcgtc cgctaccggt
    12481 cgttaaatat aaggatggtg tcgcttacga cggttttaat gacccggagc ttcgttatcg
    12541 ccagcgttac gtggatttgg tagtaaacga gggtgtaaaa gatattttca tgaaacgtgc
    12601 ggctatcatc aagaccatgc gtaccgcctt ggatgaggcc ggatacacgg aggtagagac
    12661 tccgatcctg caatctatcg caggaggagc cagcgcacgt ccattcatca cgcatcacaa
    12721 ctctttggat atcgatctgt atttgcgtat cgctaccgag ttgtatttga aacgattgat
    12781 cgtcggtgga ttcgagggtg tatatgagat cggtaagaat ttccgtaacg agggtatgga
    12841 ccgtacgcac aacccggagt tcacttgtat ggaactttat gtccaataca aggactataa
    12901 ctggatgatg agcttcactg agaagctgtt ggagcgtatc tgtatcgccg tgaacggtac
    12961 gagcgagagc acgatcgacg gtaagacaat cagcttcaag gctcctttcc gccgcttgcc
    13021 gatcttggag gcgatcaagg aaaagacggg ttacgacttg gaaggtaaga ccgaggacga
    13081 gattcgtgcg atctgcaagg aattgaagat ggagatcgac gatacgatgg gtaaaggtaa
    13141 attgatcgac gagatcttcg gggagttctg cgagggtacg tttatccagc cgaccttcat
    13201 catcgactat ccggttgaga tgagtccgct gactaagatg caccgtagca aaccgggatt
    13261 gaccgaacgc ttcgagttga tggtaaacgg aaaggaattg gcgaacgctt atagcgagct
    13321 gaacgatccg atcgaccaag aagaacgttt caaggagcaa ttacgcttga gcgagaaagg
    13381 ggacgacgag gcgatgttca tcgatcaaga tttcttacgc gcccttcaat tcggtatgcc
    13441 tcctacgtcg ggtatcggta ttggtatcga ccgtctggtt atgttgatga ccggacagac
    13501 aacgatccaa gaggtattgc ttttccctca aatgcgtccg gagaaaaccg taaagaaaga
    13561 taacgccgac aaatacgtgg ccttgggcat ttccgaggag tgggttcccg ctttgcagaa
    13621 agccggctac ctgacggttg acacgctgaa agaagcgaac gccaacaaat taagacaagc
    13681 gctttgtgag cttaataaaa aatataagtt agaactgcaa aatcctacga tccaagaaat
    13741 agaagcttgg atagccaatg taggagaata aaagcgtgat acgatggatt tgcccggaaa
    13801 aatcgcgata atgggaggtg gtagctgggc taccgcctta gccaagatcg tactttcaac
    13861 tcaagatagt atcaactggt acatgcgtag gcccgatcgt atcgaggagt tcaagcagtt
    13921 gggacacaat ccgtgttacc tcaccgccgt gaaattcgac acgaacaaga taaacttcta
    13981 ttccaatatc aaccaagcga tcaaggactc ggataccttg atcttcgcta cgccttcccc
    14041 tttcttgaaa caacatttga agaaggtgaa gacctctttg aaagataagt ttatcatctc
    14101 ggcgatcaag ggtatcgtac cggatgagaa tatgttgatt acggattact tcgcggagta
    14161 ttacaaggtt ccaacagaaa atatagcagt tatcggtggt ccctgtcatg cggaagagat
    14221 cgctctggaa cggctctcgt acattacgtt ggcttgttct gacatcgaga aggtccgtac
    14281 gatatccccc gttttcaaga atcaatactt aaagaattcc ttctgtaagg atgtgaccgg
    14341 tatcgaatac gccgccgtac tgaagaacgt gtacgctatc gccgccggta tttgccatgg
    14401 aatgaaatat ggcgataact tccaagccgt atttatctcg aacgctattg aggagatgcg
    14461 taatttcgtg gacgccgtac acgggctgga gcgggatatc accgactccg tctaccttgg
    14521 cgatttgctg gttaccgctt attcccggtt cagccgtaac cgtactttcg gaaccatgat
    14581 cggtaaagga tattccgtga agacagcgca gctggagatg gaaatgatcg ccgagggata
    14641 ttatggaacc aagtgtatgc gtgagatcaa cgagaaatat aaagtgaaca tgccgatact
    14701 ggacgctgtt tatgatatat tgtacgagaa gaaatcgccg acaacggtca ttcgtcaatt
    14761 aacggaaacg tttaaataaa atagcatatg aaaaacatca gtttaaacat cgacaaggct
    14821 ctgggcactg tctccaagga acaggtttac gctcaagagg ccaaggcaat ggaatgtatt
    14881 gccacattac ataacggtaa cggagcaggt aacgactttt tgggttggtt acatctcccc
    14941 tcttctatca cggacacaga gttggccgac atcgagaata cggcgaacgt gcttcgttct
    15001 aaatgtgagg tggtcgtagc cattggtatc ggtggtagct atttgggtac caaagcggta
    15061 gtagaagcgt taaacaacag cttcgactgg ttgcaaaacg gccgtaaaaa cccggttatg
    15121 ttatacgccg gacacaatat cggagaggat tatctttatg aattaagcga agtcttgaaa
    15181 ggtaagcaat tcggtattat caatatctcc aagtctggta cgactacaga gccggctttg
    15241 gctttccgta tcttgaagaa acaattggaa gatgctgttg gcaaggaaga ggctaaacat
    15301 cgtatcgtag ctatcacgga cgctaagaga ggcgctttgc gtactttggc agatcaagaa
    15361 ggttacaaga ctttcatcat ccctgataac gtaggtggac gtttctctgt tttgactccg
    15421 gtaggtttgc tcccgatcgc cgtggcaggt atcagcatcc gcaacttggt tgctggagct
    15481 gtttccatgg aaaaagctac agacgcgagc gttcctttcg ctgataatat ggctgctatc
    15541 tatgccgcta ctcgtaatga gttatataag aacggtaaaa agattgagat cttggctaac
    15601 ttccatccga aattgcacta tatcgcagaa tggtggaaac aactttacgg agagagcgaa
    15661 ggtaaagacg gtaaaggtat tttcccagca tccgtagatt tgacaaccga tttgcattcc
    15721 atgggtcaat ggatccaaga cggtgagcgt acgattttcg aaacggttat ctccgtggaa
    15781 gctacagctc atagcgtatt ggtccctaca gatgaagccg atttagatgg cttgaacttc
    15841 ttggcaggca agcatgtaga cgaggtaaac aagatggccg aattaggtac tcagttggct
    15901 cacgtagatg gtggtgttcc taatattaag gttaatatgc cagaagtaag cgcattctat
    15961 atcggtcagt tgttctattt cttcgagaaa gcttgtggta tcagtggtta tatgttaggt
    16021 gtgaatcctt tcaatcaacc gggtgtcgag gcttataaga agaatatgtt cgccctgttg
    16081 aataagccgg gatacgagaa agaaagcgaa gctatcaaag cacgtttata atacgattta
    16141 ccccataaaa aaacggtttt ctcatcacga ggaaaccgtt ttttcgtttg aatagttttt
    16201 attactcatt taattcttta agtaaatcgc tcccggcttt gaatttgacc gagacacgtg
    16261 gagtaatcat tacttcctcc cctgttttcg gattacgtgc caatcgctcg gattgttgcc
    16321 aaggtacaaa agatccaaat cctttcatgg aaatagattc tccttcccgt attcctttcg
    16381 ccacaacagt cggtaacgca ttcactacgg ccctaacaac atttttcggc aatcctgttt
    16441 cttccacaag agattgtact aattctcctc tattcatact agataataaa tataccattc
    16501 ttcaccagaa aagagtccgg tgagaactta gttgtttaat cattgcaaat atatgaatat
    16561 ttggggaata tcaaaatatc atatattaaa aatcaatgca tacagaaata ttatatacct
    16621 aaatgcaggt ataattgaac ccctttcaga tagacaagtg agactttggt agaaatataa
    16681 ttaataagaa atagtataca gtattatgat atcacttatt catagcaagt tatagccttt
    16741 gaaaattcgt tattaatgcg ctaactagag ttctcaccga actacgtcat aatttattga
    16801 ttaattatct caacgaaata aatttatatc ccttattttt caatacatct atcaactcat
    16861 ccagataatt ataaaattta tcaatccggt tagggtgtac atgtaggtgg atcaaaagta
    16921 agcacccatt taaaccattt ttgtttcata aaatgaaatt ccattatata tcatatttat
    16981 ttaatttcaa gaagctttcc tcccatttct gttaattcca atttattacg tacctttgta
    17041 ctggttttta agaaggtaat aacatgattc aagaagcgat tatccgatat ctgcgtaaac
    17101 acaggcagga atccctttct cccaaagctg ttcttttcga tatggatggt gtattatatg
    17161 actctatgcg ttttcatgca cgggcatggc atgaggtagc gaccctccat cagctaactt
    17221 ctcggccgga agacttttat atgttcgaag gacgtactgg ggaaagcacg atcaacgagc
    17281 tataccaacg cactttccaa cgagacgcta ccgccgagga gaagcaaacg atctataaag
    17341 agaaagcgga tctattcaat acctataatg acggtgcccc catgaccggc gccgcagagg
    17401 ttctaaaaga agtggaagca tctggactgc aacgattggt tgtcaccggt tccggccaac
    17461 atagcttgat cgataagcta aaccatacct atccgggaca tttcaaccga gagaaaatgg
    17521 ttacggcttt cgacgtgaaa tatggcaagc cacaccccga accttattta atgggacttc
    17581 aaaaagcgca tgtgaagcct aacgaagctt ttgtggtaga gaacgctccc atgggagtag
    17641 aagctgccgt agcagccaat atctttacga tagccgtaaa caccggacct ctccccgatc
    17701 aagttttatt agatgccgga gcggatttac tatatccgga tatggaaaac ttagctaaag
    17761 attggaaaca aatcatcgag cttgcgaaat ccacccgatt gaacgagtat tccaaataag
    17821 cgaacataaa aaaagaggct acccgataat gaagtagcct cttctttttt atcatcgaac
    17881 ggattatttc acataatcag ccttattcaa gaaatcatag ctctgctgaa cgctggcaac
    17941 cggatcattg tttgtatatt gctcaacttc aacataccaa tcctttacgt tattagcgta
    18001 catttgatcg aagataggct tgaaattcat cttgccactt gcgccgatct ctttctcatc
    18061 cttgatatgg atagccttga actggctcgg acggttcttc aagtaagcga caggatcacc
    18121 gccacccatc attacccagt atacatccat ctcgaagaat acgtggttcg ggcttacgtt
    18181 atccaacaag aaatcataga tcaattgatc gtcgatctta cggaactcga agtcgtggtt
    18241 atgataaccg aacgcaatgc tagcggcagc ggtcttataa ccaaccgtgt tgaaataatc
    18301 gcagtacatc ttcaagtcat ccaatgtagt cttatcgtta accggcatcc acggttgaac
    18361 catatattta acgcctaact cattatgagc atcaatcgct tgatcccacc aactcataac
    18421 ctcggcttct ttttctttcg taaatgcctg tccaaggtga gcgctcgtac acttcatacc
    18481 taggtcattc accattttct taaattcagc gggagctaaa ccgtaaatct taccgttatc
    18541 atagcttgct gtctccagat tcttataacc catcttagcg gcggtttcca atactttctg
    18601 gataccttct tcttttacaa ggtctcttaa agaatacaat tgaagcccta tatatttaga
    18661 agactccgat gctgtagcgg cagcttgtcc tgatttaccg ccacaagaag ataataactg
    18721 cggggctacc aacccacccg caagcatcaa agaggcttgc ttcaaaaaat tacgtctgtt
    18781 ctgcatagta ctattaatta agtttgattg agaattttta caaaagtaag actatattct
    18841 taggtttata tctttatgga agttaaaatc ttcaaaaagg acattgtatt ttaattttcg
    18901 ttatctttgg aggatatatt attacttaaa tcatttatat catgaaaaaa ttatcaattc
    18961 tagcgatggg ccttctcttt gtcctgacca cagcctgtag tgtttccggc agtggtacct
    19021 tattcgatgg caaagatagt aacaaatgga aaatgacagg cgatgtctcc gttcaagacg
    19081 acataatgac cttgaaaggt acggatgcac tggccgtact gaaaaacggc aaatacaaaa
    19141 acttcgatct gacccttgat ttacgtacta ccccgggagg caaaggcgcc gtctggttcc
    19201 atacggaccc gaccttgaag aaaggatatc gtatcgctat caataatgac cgggctgata
    19261 aggtttggtg gaaaatgaca ggaagtcttg tttccgtgag gaatttgacc aaaagcttcg
    19321 taaaagaaga tcaatggttc aagatggata tccgggtagc cggacaagag attgatgtaa
    19381 atataaacgg cgaaccggtt gtggagtata tccaaccgac cgccccatat cgtacggacg
    19441 ctaacgccta tgccttatta tcggaaggga catttgccat agagagtgat ggtagcggtg
    19501 agatccagat caagaacatc accgtgaacg taattgatga atccacgatc gatatcaacg
    19561 cacaattggc ggaagctaac gatgagcaaa atgacgagat cattaaatta catcaatcgg
    19621 atttcccggt attagattat cacgtgcact taaaaggtgg cttaaccaag gaagttgccg
    19681 ctaagcaatc ccgcaagacc ggtatcaatt atacgatcgc accgaactgc ggcatcggtt
    19741 tcccaatcac gaacgaccaa caagtcatgg attacctaaa tgagatgcgc tcacagcctt
    19801 tcatccttgg catgcaagcg gaaggacgcg aatggataac cacattctct cccgagactc
    19861 ttaaagaatt cgactatgtg tttacggacg ctttgacgtt caaggacaat aaaggtcgcc
    19921 gtacccgcct atggattccg gaagagactt ggatcgagaa tgaggagcaa tatatggaca
    19981 tgatcgtaga tcgtatctgc tccgtattgg aagagccggt agatatctat gtaaatcctt
    20041 gtttcttgcc atctccgatg gataagcgtt ttgacgaatt ctggacggag gcccgcatga
    20101 accgtttcgt cgaggcattg gcaaaaagcg gaaaagcttt agagatcaac gaactataca
    20161 atattccaaa taaagcgatc attatgaagg cgaaagccgc cggcgttaaa ttcacgtttg
    20221 gaagtaacaa cgtgacacca aacgtcagcg atctgtctta cagtatccgc atgatgaaag
    20281 aatgtggcct gaccgctgag gatatgtata aaccgaaagt taaaatctaa tcacacattt
    20341 accctcaccc taatcccccg tttagggaca ccctaaatga gcgattaggg tagacctaaa
    20401 cgagggatta ttctctttct cgcaacatcc gtcgcatctt catataccga tattgcttta
    20461 taatcatctt gcggctacgt atgatctgat aacggtaaat gatacaagac aagatgaaat
    20521 atacacctgc ctgaatccat aatacccgat attcatgcgc cacctcatgc aaggaagcgc
    20581 cagccgtatt gatacggata aatccctgga tacccggagt agaaggaaac aaataaccca
    20641 ccactttcca aaacggagga atagccgcct ccggccaaga gacacccgag ataaataaca
    20701 agatgacaga cgtgaaaacg aacaccaaca taggcgattc gcgactcgtc ataaatcccg
    20761 ataacgtcat agacataaaa atacaggcaa acaggtaagg cagtaaaaac aacaaaatag
    20821 tcagtggctc accaacctga ggtaaggaga ataacttagg gacaatagcc aatacccaga
    20881 tgcaaaccac cacatacagc aaaagataag tcagcgactt gccgaacacg atacgcaaag
    20941 tcccgttaaa atgcctgcaa ataggtacca gactatggaa acgattcttt tcccgtgccg
    21001 ttcctcccaa cattccgatg cccaatatca aggtctgttg caataccaag atcaagatag
    21061 ccggtaccaa aaaactggca aaaccattct gggaattaaa caacgctacc gattcatacg
    21121 ggatcgggtc taccgtgatc tggtccatct tatccgtaga cgacggatta ttatgcatcc
    21181 gaagttcctt acccatatcc aacgatacct ctgtcgccgc caaaaggaaa gccttataaa
    21241 acaataaggc gctcatatcg caatacaacg agacggttgt ctgtcgccct tcatgcaggt
    21301 ccttactata atccggggga aagagcaaaa ttccataggc cttcttctca tctaacatct
    21361 tcttggcttc cgccatatcc ggacaaacac ccactacttc cacatccggc gtggcgttaa
    21421 cccgtctggt aaactcacga ctcaaatagg aatcactttg gtctaccacc accatcttcg
    21481 cctcgtgtac tacctcgtta ttatatataa atgaataaag cagcggatat acgaaaggca
    21541 ccaagaaaaa gaagatcatg acccccgcat ccttaaacac gtttctcaat tcatctttcc
    21601 aaatataaaa cgtatccaga agaccttcct ttatgatata tcgtaaacga tgttctcttt
    21661 tcatcacata cagtttttac ggtagatatt tgaaatccaa caacgctctc ttcaagttcc
    21721 gcccgataag gaagggcagg atcaagaatc ccaacaacca agcgtactcg cccaacgtat
    21781 agaatagcgc ccgcccgttc aaggcttgat cgacataaat caagaaataa tgccgcaaag
    21841 ggaacaaacg agtcaacgct tgcaacgtag ggtccatacc ttgtaccgga aacgagaatc
    21901 cgacaatgga gaacgagatc attccgaaca ggctggcgaa gctaagacct aaacggggag
    21961 tcggtaatac gccgatcata aatacgccta ccgcctgaga ggatataatc agcaaaaaca
    22021 tcgccaaaag catcggaaac caaccgctat ttaacgggaa agaattaatt ccatacaaca
    22081 ccgcacaata cataaagcct acgaccgtaa aaatagctgt ctgcggcaat aactttccca
    22141 acaaactaac tgcgatggaa ttccctccca tatccaacca tttacgggat gtggaatatt
    22201 taatttccgt accgatactg aatactgtca ccagaaatac catcaactga atgatacccg
    22261 gcaaaaccgt attattcaaa tataccgaat aattcaacca cggattgccg atcgggtgcg
    22321 tatcgatcac gatcggttgt agctgtccca tgatctgcgc ttcggtatat cctttagctt
    22381 gtccggtctg taaacccaca gcggcccccg ccaataccga cattgttttc atatcccgaa
    22441 acagcaagga agcggcgatc aaataggtac cattcgtata gaaagacaac cggggctgct
    22501 ttccagatgt ggcgtccacg gcgaaaccgg atggaatgta aaaaattcca tatacattcc
    22561 ctttctgcat ttcctgacga gcctcggtaa acgacatggt tttcatatac acctctgtct
    22621 gctcaaaggc atccaactgg cgaatcaaat tgcgtgaggt agcagagtta tccatatcca
    22681 ccactgctat cggcagatcg gtcggcaatc cctcatgcat caacgataca aagaaaatga
    22741 cacagatagc cggagcgatc agcatacaaa agaagtaaat cggttgagcc accagccgat
    22801 gcacctcacg cttcgtgata agccagattc tatgcaaact ttctttatag gtcatacgat
    22861 ctctttccct tttttcttta agatcacgga cattcccgga cgaagatcag cgactttctc
    22921 caacggacgg gcacgcacct cgaaagtctt cgagtcatat tgtccattcg tctttgtcgc
    22981 tttccatgcg gcatacgagc ccatatcctt catataatag actttcaact tcaccggtag
    23041 gtcccccaac gccgggataa aagcatttac ttccgagcca atcttgatat ctttcaacag
    23101 atcctcacga atactgaaag ttacccatac atcatttaaa tcagagatat tcatgatcgg
    23161 agcacctgta ccaaccaact cgccgacttc cgggaaccgt tctgaaacct ccccgtcaat
    23221 cggagccacc aaagcgctct cgcccacata cgactccact tcggcgatag caccttccgc
    23281 acgttggacc atagcggcag cggcagcctt atcttcctca cgggcacctt cttttgccat
    23341 ctcatattga gaacgggcag ccttctctgt cgctaccata gcgttataat tagcctccac
    23401 ctcgtctctt ttttgagcgg acatcacccc tttctcgtat aaattctgaa tacgatcgaa
    23461 agatttctta gcgatagtta atccggcttg cgccttttgc cacatctcat aagcggccgt
    23521 aatttcctgt tcacgggctc ctttaatcgc tttagcgttc tgcgcctccg ctgccgcacg
    23581 agccgcctcc gcttgtttca gcttcgccat aacctcgggc gtatctaaaa agaccaaagt
    23641 atctccggct tttacctgat cgccttcgcc aaaacgataa gaagcgatac gtccgggaac
    23701 cttaccggag atacgaactt gggtggcctc ggcctgcccc attataatat cgtcaggcgg
    23761 tgtaagcagg aagaaacccg ccaaggctac caatccgatc acgaccaata ccgtgataaa
    23821 agctaacatc atgttactga tagaaaactt cttgttctcg ttcatctctg tgtatatttt
    23881 tatttgttat tactcttatt catttgcgga cagtttaccc aaagccttgc ttagataaac
    23941 ttctgttaat ttcacctcga tttgagcatc aatcaaacta gagcgagcag aaacccatgc
    24001 tgtctgcgcc tccattaagt tcaaagccgg gataacccct tcctcaaaac cgaaattcgc
    24061 acgccgcaaa ttctcttccg cattttccat attacgggaa gaagcgatca actttttgcc
    24121 cgcttcattc actttataaa cggattgatt tacctgcaac tcgatctttt cacgagcatc
    24181 ctgccattcc agtgttttta tgcgcgtttc cgctttcgcc gagttacgcc tataagtgcc
    24241 ttcccaccaa ccggacaagg gtacctttac cataactccg acattaaaca taccggcgaa
    24301 atcattttta aaaccattaa aaacattcgg attcgtgacg aagtaattcg ccgctaaagc
    24361 gacattaggc aacatctctg ccaaagcaat acgttctttt cgcttataga ttttcgttgc
    24421 cagatccaaa cttctcagtt cattacgatt catgaaagcc tcattcagat cggccgaggc
    24481 ttgtgttgtc tctaccggaa aattatccag cttctcgtct gcaagcgata aatcctcctc
    24541 taaagacaga ccacaaattt gcgctaaaag cattcgggtt aaagccagac cattctcaac
    24601 cttagtctga gccatctccg cctcattcag tttcaccttg acagaaagac catcggcctc
    24661 ggtagcgact ccctcataga tcatagcggt cacatcacta tccatcttac ggagcaaatc
    24721 cacataagcg tccgccaatt tcttcttatt caccaaagat atgacctgcc aataggtttc
    24781 gtcagtctta taaatcaagt cctgcaactg taaattattc attgactccg ctaattgctt
    24841 ggcaaactta gtgatttggt tataattaac gatcttccca cccatgaata caggctgtac
    24901 caacgataca ttacccaccc agatattctg cacatccaaa tgttgcatat cgttcacccc
    24961 actcatcaaa tgttggatca tcggtaattg ggccaagcca cctaaagaag agctcaagga
    25021 tgaggacaaa gcgcccatgt ccagtaagtt tatatccttc tggttccaca tataggcacc
    25081 gtttgccgat aattgaggaa aatacttggt aaaagcggct ttcttctcgt tatccgccat
    25141 cttgatcttt tcgccagaga tttgtagctc cttattgttc tggatcgcca gattccggca
    25201 ctcttccaat gtcaacattc gctgagcgtg catacagctc accgtgacta caaatgttaa
    25261 tagtaagata gttcgtttca tctttatatc gttttaacct acctatataa tgccatcata
    25321 ttccctatgt gacaaaaata taaaaacccg cacaaaagta taggtttaaa gcgaatataa
    25381 aattgaacta attcaataaa ggatacgttt cttcaactta caataccaag aatcactaac
    25441 ccccatatat tgagctatat atttatcagg gacccggctt acgatccatt ggtggttcgt
    25501 ataaagatat ttcaggaatt cttccgcctt acaggtttga cggacagcga acattgaata
    25561 gagcttggaa ataatcatca gcatcacatt ctgataacag gtagcgaaag ctggatatcc
    25621 caacgacaaa cgttcgatat ccgtccggga aaaacagagc aattcaccat cctcgatagc
    25681 tttcacctca aactcggaag ggacttgtgt aaaataacct attgtagaaa caaaagggta
    25741 catactatcc gaggagaaac cggttacgca ttcattccca ttctcattaa tatattgatt
    25801 gataaaaagc cctttattaa taaaataggc atcttggcac aactcgcccg tacgaatcaa
    25861 ataatcccct ttccggattg tcacacctcg agtacaactt tccaaatcct ttaggaaaga
    25921 ttcatctcga gacagaatct ccggaataaa acttaggaac ttctcaaagt cgggagataa
    25981 tttcatagtt aatcatccaa ggtaaatctc ttctgtccga tcaaattacc gtcagagaaa
    26041 atatccacac ggtaagtacc cggagataag aattcctcga tattccaata catggtcact
    26101 gccacctcct caccttcata ttctatcatt ttcttcatag aataattgat ttcctttcct
    26161 tcaaaagcga atacatccgc acggcttttc accaatatat cgtcatccgg tttcatgatc
    26221 cgtacatata ccatcttttc gccgacagga gcggtaatgt tcttcgctat cttgaaagtc
    26281 acgacgaatt gctgcatctt cttaatacgc ttagcgagtt tacctcgaga gttcacagga
    26341 gtcacgttaa tatccgtcgc atccaaacga ctagctaacg ttactctttc cgtcaatttc
    26401 tctttttcct ttttcaaggt agcagcttgt gaagtagccc tctgatattt ctgaacagcc
    26461 tctttctttt caaccttcaa ttgctcattc tcacgattca aggaatcgat ttggacaaca
    26521 tagttacgca tgattttacg taaggtatcc aattcctttt tcaagcgagc tatttccttc
    26581 gcattcgtag ccttcaccgt acgcaattct tccaataaac gttgtacctt tgcttgctcc
    26641 gtagataata gggcaacaag ggaatcattg cctacgctaa acttataacc ttcatattga
    26701 agagacaatt cattatattc atcctccaaa gattctttct caagatcaaa ggtttccacc
    26761 aaatcagtca tttgctgctt ttgatgataa atataataac cggcaccagc aataatcagt
    26821 accaatacta taactgctac gataagtagc gaaagtttat ttacttcttt attctctttc
    26881 ttttcagtat ccatatgagg ttcttagcta ttacaaaagc acaaaattac aatttcttat
    26941 ccatccgaac aacaaagtac acctaaaaat agaaaaaggc agagaggata tataccaaaa
    27001 aaaggagtca ccccttacgg actgactcct ctctcttccg gctttcgcct ttctcaagac
    27061 ggcggctacc tactcttcca ctgttacgca gtaccatcgg cgtgacgagg cttaacttct
//
LOCUS       DBMDTB010000053        26764 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_648_length_26764_cov_10.861981, whole genome shotgun sequence.
ACCESSION   DBMDTB010000053 DBMDTB010000000
VERSION     DBMDTB010000053.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 26764)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 26764)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26764
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_648_length_26764_cov_10.861981"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..421)
                     /locus_tag="ACZPB4_09795"
     CDS             complement(<1..421)
                     /locus_tag="ACZPB4_09795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M19"
                     /protein_id="HIR1098543.1"
                     /translation="MNKPFIIDAHLDLSMNALEWNRDLREPLKEINRREIGMTDKPDR
                     GNATISFEELRKGNVGLVVATQIGRYVGPDNPLPGWHSPEQAWAQTQGQLAWYKAMEE
                     EGQMVMIRDKKALEAHLALWKDGEPADKKPIGYVLSIE"
     gene            complement(462..1565)
                     /locus_tag="ACZPB4_09800"
     CDS             complement(462..1565)
                     /locus_tag="ACZPB4_09800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-TA family PLP-dependent enzyme"
                     /protein_id="HIR1098544.1"
                     /translation="MDDWYVISNVDRIDSPALAFYPDRISGNIELAKRIIGDTNRLRP
                     HVKTNKAAEVSRMLLDAGIRKFKCATIAEAEMLGHMNAPDVLLAYQPVGPKISRLLDL
                     IKAYPATHYSCLVDQAENARAISALCEAGNITLDVFIDLNVGMNRTGVLPERAEALVD
                     AILPLKSLQIIGLHGYDGHIHDAELSVRCQGADAAYALTERVFREISRKFAYPLVKVM
                     GGTPTFPMYAKRKDCECSPGTFVFWDWGYGNAYPDMPFKVAALLITRVISVLDEHHVC
                     VDLGYKAVASESPLPRVFFLNHPEAKPISQSEEHLVLEVPDSRLYPLGSVFYGIPVHI
                     CPTVALYDKAYVIRDREAIGEWPIIARSRRITY"
     gene            complement(1569..2042)
                     /locus_tag="ACZPB4_09805"
     CDS             complement(1569..2042)
                     /locus_tag="ACZPB4_09805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HIR1098545.1"
                     /translation="MSMINADENFEKLGLTLPPAPAPAGVYKPCVIDGKYLYLSGHGP
                     VRNDKSLIIGRIGKDLTMDEGKLAAQQVGLTMLATIQANLGSFNKIKRVIKVLGMVNC
                     TPDFGKHPYVINGCSELFAAVWGPDNGVGTRSAVGFGSLPDNIPVEIEALFELYE"
     gene            complement(2083..2604)
                     /locus_tag="ACZPB4_09810"
     CDS             complement(2083..2604)
                     /locus_tag="ACZPB4_09810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4833 domain-containing protein"
                     /protein_id="HIR1098546.1"
                     /translation="MRKRWLLSIVIMLFPFVASFAADPEEGTYPTVGRLFHIARSVNK
                     NLVCYDVNLRDGKLDTHDPLNVYWVNREKHPGETNGLSYIQRKMAYGYKLISASDNAC
                     VCSLTAYPSRQLTITKRDSRYVCYITINNQQAILQSLYVKASSKNPLSVEYVELQGIS
                     VATNQPVTERVRK"
     gene            complement(2623..3942)
                     /locus_tag="ACZPB4_09815"
                     /pseudo
     CDS             complement(2623..3942)
                     /locus_tag="ACZPB4_09815"
                     /inference="COORDINATES: protein motif:HMM:NF014500.6"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015128 - gluconate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0035429 - gluconate transmembrane transport
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate:H+ symporter"
     gene            complement(4006..5097)
                     /locus_tag="ACZPB4_09820"
     CDS             complement(4006..5097)
                     /locus_tag="ACZPB4_09820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1098547.1"
                     /translation="MLRYLLEKEFKQIRRDRFMPKIIFIIPIMQLIILPFAANFEMRN
                     INLSIVDNDHSVTSMQLVDKVLSSGYFRLTDRSDRYDEALTSVESNESDIILEIPSDF
                     ERDLGKEGRADVMIAANAVNGTKGGLGSSYLSSIIQDFNREKGFASMGSGRGVASINL
                     FNPHLSYKIYMVPGIMVFLLTIIGGSISALNIVSEKEKGTIEQINVSPVPKSLFLLSK
                     LIPFWVIGFVLLTVAILIAWLIYGLVPEGSFGVIYLFAAVYLIAFTGFGLAISSFSST
                     QQQAMLTAFFFLIIFALLSGLFTPISSMPEWAQKITLANPVRYFVEVMRMVYLKGSGF
                     ADLRGHFVIVCLFAVFFNLLAVISYRKKG"
     gene            complement(5101..6186)
                     /locus_tag="ACZPB4_09825"
     CDS             complement(5101..6186)
                     /locus_tag="ACZPB4_09825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1098548.1"
                     /translation="MKQFISFVRKEFYHIFRDARTTMILLLMPVILIILFGYAITTEI
                     KRVPIAIFDQSRDELTLKMADRLNASEYFELYTTVDSYEDAEALFRQGKVHVIVVFPP
                     QYASTADAQVQVLADATDPNEATQLIAYCSAIIAEQLKGESAVESKAVTPVTTLLYNP
                     QMKGAYNFVPGVMGLILILICAMMTSIGIVKEKEMGTMEVLLVSPLKPIYIILAKAIP
                     YLLLSMVNIATILLLSYFLLDVPIKGSLLLLVSVSILYAIVSLCLGLLISTVADTQQA
                     AMLISGIALMLPIMLLSGMMFPIENMPDILRWFSHIVPAKWYIIAVKDVMIKGLPAVS
                     ILKEIGILSFMAVVLVFLSVKRFKIRL"
     gene            complement(6190..>6880)
                     /locus_tag="ACZPB4_09830"
     CDS             complement(6190..>6880)
                     /locus_tag="ACZPB4_09830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016273870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1098549.1"
                     /translation="FTAVDHISFEVEPGEIFGFLGANGAGKTTAMRMLCGLSAPTSGE
                     ARVAGFDVYRESESIKRNIGYMSQKFSLYGDLKVWENIRLFGGIYGLSKRQLSQKTDE
                     LLDILGLEKERNTLVDSLPLGWKQKLSFSVAIIHDPKIVFLDEPTGGVDPVTRRQFWE
                     LIYEAAARGITIFVTTHYMDEAEYCNRVSIMVDGKIEALDSPSALKRDFKTTNMNQVF
                     HALARKATRGE"
     assembly_gap    6881..6980
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<6981..7633)
                     /locus_tag="ACZPB4_09835"
     CDS             complement(<6981..7633)
                     /locus_tag="ACZPB4_09835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1098550.1"
                     /translation="MNNEIHINHITKRYGDVEALRDLSLEIGSGELFGLIGPDGAGKT
                     TLFRILTTLLLADSGTASVCGLEVVKDLKEIRRRVGYMPGRFSLYQDLTVEENLNFFA
                     TVFNTTIEENYDLVRDIYSQIEPFKHRRAGKLSGGMKQKLALSCALIHRPDVLFLDEP
                     TTGVDPVSRSEFWDMLDRLKRQGITILVSTPYMDEASRCDRIALVRSGECLSIDTPVG
                     "
     gene            complement(7626..8516)
                     /locus_tag="ACZPB4_09840"
     CDS             complement(7626..8516)
                     /locus_tag="ACZPB4_09840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HIR1098551.1"
                     /translation="MRHLIFISLCSLLWTACGNTDNDFDASGTFEATEILVSSEANGK
                     IMELNIEEGDRLDAGAIVGYVDSTQLFLRKMQLSASLRSVDIRKPDIRKQIAVLEQQI
                     ATAKTEQQRQENLVRAKAGNQKQLDDIVNNIKYLQKQLDAQYSSLSKTTGGADAEAEG
                     LQYQIMQLDDQLMKSRILNPQTGTVLVKYAEPGEVTAAGKPLYKIADTDLLYLRAYVT
                     ADQLSHLKLGQSLKVFADYGNDRREYPGTITWISDKSEFTPKGIQTKDERANLVYAIK
                     IAVRNDGYLKIGQYGEIKYE"
     gene            complement(8544..9830)
                     /locus_tag="ACZPB4_09845"
     CDS             complement(8544..9830)
                     /locus_tag="ACZPB4_09845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HIR1098552.1"
                     /translation="MRGVYVLLLISLLGYTGRVSGQESVTITQCYEWARANYPQIHQM
                     GLIDQTERYSLSNVGKAWLPQLSVSGKASYQSDVTKLPFDGDKISSLLPGFEIPSLSK
                     DQYQVVAQVDQTIWDGGSARSARALTRAEATANREQLESELYALNDRVNQIYFGCLLQ
                     DELIRQNALLQKELQVNIERIKAMMDNGVANQSDLESMEVELLNARQNEIELKASRTV
                     YRQMLATFINKPLTDQVVLKTPESPERSLFTQINRPELRALDAKSEWIETQNKQVTAG
                     LMPRIGAFVQGGYGRPGLNMLEDSFEPYYVAGVRLSWNLGKLYTLKNDRRKIEVSRRQ
                     IDVQRETFLFNTRLQLLRQNTEIKKMTDLMRADDDIIRLRTSIKQAAEVKLENGVISV
                     TDLIREINAEDMARQTAAAHRVQRLMTIYNYMYTTN"
     gene            complement(9868..10497)
                     /locus_tag="ACZPB4_09850"
     CDS             complement(9868..10497)
                     /locus_tag="ACZPB4_09850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HIR1098553.1"
                     /translation="MEAKDMNEMEPRIIEAAKRVFVRKGYEAATMSDVAAEVGIGRTA
                     LHYYYRTKEILFDAIFGQLLSSLLPNIDRVLDEKSTMLEKMPVIVDLYMGIVRANPMF
                     PNFVVGELNRDPERLFQTVLKDPKKIQPILRLRRQIEEEMDKGLLRKMPVIDLVSTLV
                     SLVVFPLLIRKPLAAAFLDNDMGRFEEYMDRRRDLIVEVITQLMVPDAR"
     gene            complement(10708..11712)
                     /locus_tag="ACZPB4_09855"
     CDS             complement(10708..11712)
                     /locus_tag="ACZPB4_09855"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HIR1098554.1"
                     /translation="MINGKKSLFYTVLMAGALMSCGGPKQAPSEEVAKSGNPVFEGWY
                     ADPEGIIYGDTYWIYPTTSDLYEKQTFFDCFSSKDLVSWTKHTAILDTAEVKWAKIAM
                     WAPSVINKDGKYYLFFGANDVHEGEIGGIGVAVSDRPEGPYKDLLGKPLINEIVNGAQ
                     PIDQFVFHDADNDEYYMYYGGWKHCNMVRLNKDFTGLIPFEDGTIYKEVTPKDYVEGP
                     FMFKKNGKYYFMWSEGGWTGPDYKVAYAISDSPFGPFNRIGEVLRQNFDIANGAGHHS
                     IMHVPNSEDYYIVYHRRPAGVKTRDHRETCIEKMTFNEEGLINPVEITTEGVEARTIQ
                     "
     gene            complement(11752..12963)
                     /locus_tag="ACZPB4_09860"
     CDS             complement(11752..12963)
                     /locus_tag="ACZPB4_09860"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008771936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase"
                     /protein_id="HIR1098555.1"
                     /translation="MESIKQIYRMGHGPSSSHTMGPMRAAQMFLERNRGAVRFNVTLY
                     GSLAATGKGHMTDAAILEVLQPVAKTNITWEPKTFLPFHPNGMLFESYNESGEELDTW
                     TVYSIGGGTLANESFNELRTEQVYDMHTIKEIQAWCEKTGHSYWEYVEQHEGPSIWDY
                     LAEVWEVMQDAVRRGLEAEGILPGGLGIRRKASDYMIRAKGYGSSIKSRGMVYAYALA
                     VSEENACGGKIVTAPTCGSCGVMPAVLYHLKETREFRDSRILRALATAGLFGNVVRTN
                     ASVSGAEVGCQGEVGVACAMAAAAASQLFGGTPAQIEYAAEMGLEHHLGLTCDPVCGL
                     VQIPCIERNAFAAARALDANTFSNFSDGKHRVSFDQVVEVMRQTGNDLPSLYKETSEG
                     GLAKNMENSNN"
     gene            complement(12991..14127)
                     /locus_tag="ACZPB4_09865"
     CDS             complement(12991..14127)
                     /locus_tag="ACZPB4_09865"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008771935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HIR1098556.1"
                     /translation="MEKKKLNRLESLDVLRGFDLFCLVVLEMVLHPLAHAIDMPWFNS
                     FMWGFSHVEWEGFSTWDLVMPLFLFMAGVSMPFSLSRYKDMPDKMAVYRRIGKRVLLL
                     WVFGMMCQGNLLALDPDRVYLYSNTLQSIAMGYLIASLLFLHVRIRVQIGIAASLLLI
                     FWGTMEFITVGNYGGGSYTPDSNLAEWIDRTVLGRFRDGATVENGEVIFATWYRYTWI
                     LSSLNFGVTVLTGLFAGYILKNKLYSERLKLRMLFGIGLGMVIAGWLWGIELPVIKKL
                     WTSSMVLVSSGYCFLLMGLFYYWIDYKGHRKYTTWLKVYGMNSILAYMLTNVVSFRCI
                     GESLFFGTQQYLGNYYPVLIAMCNVSVIYVLLYAFYKHNIFLKV"
     gene            complement(14135..15253)
                     /locus_tag="ACZPB4_09870"
     CDS             complement(14135..15253)
                     /locus_tag="ACZPB4_09870"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HIR1098557.1"
                     /translation="MEKQKQQPQRLQSLDALRGFDMLFIMGGASLFVALATLFPNPFF
                     QAIAGQMEHVEWNGLAHHDTIFPLFLFIAGISFPFSLEKQRGKGMTEGAIYKKIVRRG
                     ITLVFLGLVYNGLLSFEFDHLRCASVLARIGLGWMFAALLFVRFGWKARAGITALILV
                     GYWLVMAFVPVPDAGGAGPFTLEGNLVGYIDRLFLPGRLHETVFDPEGLFSTVPAIAT
                     AMLGMFTGEWIKLGKEGLTDRKKVLCLVGAGAVLLIVGLLWSLVFPVNKKLWTSSFVC
                     VVGAYSVWMFALFFYIIDVLGWRKWTLFFTVIGMNSITIYLAQRFIRFSYTSEAIFGG
                     LAKLMPETAQPLVSAIAYIAVCWGFLYFLYRQRIFLKV"
     gene            complement(15381..16538)
                     /locus_tag="ACZPB4_09875"
                     /pseudo
     CDS             complement(15381..16538)
                     /locus_tag="ACZPB4_09875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008648946.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            complement(16769..17521)
                     /locus_tag="ACZPB4_09880"
     CDS             complement(16769..17521)
                     /locus_tag="ACZPB4_09880"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HIR1098558.1"
                     /translation="MLPLVSIITPCYNAAPFISQAIESVLAQSFGDWEMIIVDDCSSD
                     DSLSIIQEYARIDSRIRYLRTDKPSGSPTLPRNMGIKEAKGRYIAFLDSDDIWLPNKL
                     SDQLKVFEKSEVAIVFSNYEKVSLGGERCGREVIAPCEVDYPLLLKGNCIGCLTAMYD
                     SALTGKIFFKEIGHEDYVCWLSILKQGYKAQNTNTVTALYRVSDHSVSSNKLKAMRWQ
                     WNILRNEMDLPVYKAVYYFIHYAIRAFAKAMR"
     gene            complement(17538..18995)
                     /locus_tag="ACZPB4_09885"
     CDS             complement(17538..18995)
                     /locus_tag="ACZPB4_09885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0031419 - cobalamin binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="B12-binding domain-containing radical SAM
                     protein"
                     /protein_id="HIR1098559.1"
                     /translation="MNIYFINPPFKAEYGKFSRESRSPAITKSGALYYPLWLIYAALY
                     SSKQGHNVSFLDAPAKQLNEEQSLNIIRKTDNEHSLFVLDTSTPSIKSDVAFAGKLKA
                     LYPHSFVVLVGTHPSACAEETLGYSNAVDAVAIGEYDCIVNELANVLDAGKDLREVRG
                     LCFWDGKEFVRTAPMPPMKNLDDLPFASQFIKEHLNERDYFFAAATYPSIQIFTGRGC
                     PFRCNFCVYPQTMHGHAFRARSAENVVAEFEYIAANFPDVKEVVIEDDTFTANKKRVL
                     DICRLLVEKKLNKRLKWLCNARVDLDLETMLAMKKAGCRLIIPGIESGSQQILDNIKK
                     GTKVEYFYQYVANAKKAGLLIHACYMVGNQGETRETMEETLRLALRLNTDTAQFFPLI
                     PYPGTEAYQWARENNYIETDYEKYCLPDGTHNTVLSLPDLSAGEMVDFCNRARKKYYL
                     RASYILHRLRVGLRNPSDLKRSLKAFAKLKRYLFK"
     gene            complement(19029..20147)
                     /locus_tag="ACZPB4_09890"
     CDS             complement(19029..20147)
                     /locus_tag="ACZPB4_09890"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009101 - glycoprotein biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HIR1098560.1"
                     /translation="MNILFDLSGCNQPYNAITVYGLRILAGFKENGYKDISILCDARI
                     YDHVHVTFPEYPCLEIAFDTGRNPMTLLRNFRHWKNTVKNIEHDVLFVPHVFPPNFCF
                     HRRDKTVLVLHDLQGLRIYKGLRLWACRFFYPLALWRCKASIVISDFVREDVRKTYPF
                     ISPRKLNTIYNGVVVDQLPQKRDTLPVKGKYLLYVSSLMEHKNVMTLLRAFNRLKDKI
                     PHTLVIIGKTRPVWTEKALPFIQEENLSSRIYHVTKPVSDETLAQYYNQADLFIHPSL
                     MEGFGYTPIEAAIYGTPVLTNKETALFETTMGLLNYYEPATDDKAMANEIERLLTNPI
                     SLDRLSEIASTFRERYDNTKQGKKIYDLLISLSMDSKG"
     gene            complement(20161..21192)
                     /locus_tag="ACZPB4_09895"
     CDS             complement(20161..21192)
                     /locus_tag="ACZPB4_09895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpsG family protein"
                     /protein_id="HIR1098561.1"
                     /translation="MIYYTLPILSFVIAFIRLNKRRCTPLVVILLLLCFVVGALRGEG
                     VGADYYAYLRIFLHGDETMEAGFSELIRIIKWFGGDYFHLIVLVFSLSFFTKYYVFRK
                     MSPNPYLSLMIYLGFWFLSYEMNGIRQGLALGFIGVAVYHAWKGKMFFYWIFIGLAIS
                     VHNSALVFLPFAFFVGRPCTQGIQLIFLFIYVVLLFVDVLDPLISKIGGDLYAVKKVM
                     DYSMDDFYNGNILYSFSTVHRVMITGLIVYAVPRMKIDDRLKNIFLWSALFNMAIYLL
                     FGQIEIVATRLSLNYRFVECMTLAGLPSLPSRKENRLIIAYLLFGYVLIQVYSVLSIP
                     DGKLIPFHF"
     gene            complement(21192..22013)
                     /locus_tag="ACZPB4_09900"
     CDS             complement(21192..22013)
                     /locus_tag="ACZPB4_09900"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009101 - glycoprotein biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HIR1098562.1"
                     /translation="MISLITATYGRTEEVRTLLGSLARQSYKDFEFILVDQNPHFILR
                     EMVAEYASRLTIQYIRSEAKGLSLNRNIGLDYSRGEIVAFPDDDCFYEEDVLEKVIDV
                     FQRQKDIVLVATAVKDAFDGRVWKVSERELISRNKTLRYCFSNNIFVRKTEARFDVRL
                     GVGAYWGSGEESDYLWEILDEKDVGIFLRDTYINHPYIADVFVNIPKAYAYGLGFGAL
                     FKKEVVGRKHYAFLFRFIYYVLRSVGGCLLSRHTKYYYYTLRGRIMGFVTFPVSM"
     gene            complement(22052..23980)
                     /locus_tag="ACZPB4_09905"
     CDS             complement(22052..23980)
                     /locus_tag="ACZPB4_09905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098563.1"
                     /translation="MKRNTRVIYSFDLFDTCFIRACGAPRNVFDLLAYRVLGANSDES
                     ARADFALERVKGERKARALSQVEEITLEAIYVCCDFMALTAQSKTEIARLEMQVEREQ
                     LVPVYAIREKIKTLHREGHSVYYISDMYLPRTFLSELLIEHGFWREGDKLYVSSACGK
                     TKHTGNLYKHIAAENGLRFKDWYHWGDNRHSDYRIPRRMGIKASLIHHVYSVYERFLV
                     RQDYFPGFFVNQHLAGLSRAVRLAFPDEPRYAFAADLIAPLYVAFVYHVLRDAVSRGI
                     RSLFFLARDGYILYRIAKELEGEFPGLRMKYLYVSRSSLYLPGLPAITPDSLLSLRKT
                     MFGFTDETELDILGNFITSETWHEVECVMRSGSGSGKGEELFANPEVLAILSRYHDTQ
                     RDLILRYFIQEGLADPIHKTVVVDIRGTRSCQQAINAILRQGGFRPAEGYYLEVVDER
                     KPIQEAGDYHALYYAERMRLSSSLRYISDELGSILEQYFSVSPHKRTIAYLEDDGRVR
                     PVFENGEKEGDTRDLMTCHEETVALFTRLFMRNYLYLHLPATLALATQSLAYFSQRPV
                     YSYLKALRAIRVNSKKGHYAYIVKRLSPMELKRHTVNWRRGSVYFTLRTTMGYRYINR
                     VFLFGVEALKRLLSHLNG"
     gene            complement(24023..25462)
                     /locus_tag="ACZPB4_09910"
     CDS             complement(24023..25462)
                     /locus_tag="ACZPB4_09910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HIR1098564.1"
                     /translation="MSESIKNKAIRGVAWSAVEKFARQGLMVFFSILIARQLSPADYG
                     LVAMLTIFLVVAQIFVDSGFVEALIQKRDRTEVDFSTTFWFNIGVAAAIYGVLFLLSP
                     LIAGFYGEPLLEELTVWMGLIFVINSFRTVQQAKLNIAMDFHRQAWISLVAISVSGGT
                     GVWMAYRGFGVWTLVWQALLQNLLNVALLWVSAGWMPSLVFSRRSFRYFFKFGSKILI
                     TRVLHTLYMNGSYLLVGKFYSPALTGLYSQAVQMTSLLPNSIDETLSRVAYPIECELQ
                     NDNEALRHTFYRFVRLNAFIVFPLMTGLAALAEPLVRLLLMEKWLDVVPLIQILCFGW
                     IWQPLSGLNWQILNVKHRSDYYMKSEIFKKIIAFTILFSTLFMGLVVLCVGWVIYCII
                     DLYVITLYTRRLLPAITFKNEMRVLVPILLRALSMGGVVYLLNYAVDSDILRIALGVP
                     LGCVLYTGISLLTRSEEIHYLIDMIKKRK"
     gene            complement(25764..25874)
                     /locus_tag="ACZPB4_09915"
                     /pseudo
     CDS             complement(25764..25874)
                     /locus_tag="ACZPB4_09915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005822563.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding domain-containing protein"
     gene            complement(25925..26569)
                     /locus_tag="ACZPB4_09920"
     CDS             complement(25925..26569)
                     /locus_tag="ACZPB4_09920"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009101 - glycoprotein biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HIR1098565.1"
                     /translation="MLIKESVDKSTDFIPDGMTAFERNVKRIGDCLLAFIALVVFSPL
                     FLICYIAVRREDGGPAIFRQERIGRFGRPFHIYKFRSMRLDAEKFGPALYKGGADPRM
                     THVGKFLREHHLDELPQLWNVFIGDMAFIGPRPERKFYIDQIMEHDPRYRFLYQIRPG
                     VTSYATLYNGYTDTLEKMLRRLRYDLFYLEHRSWWFDFKILVKTFLNIAFGKKF"
BASE COUNT         7518 a         7170 c         5455 g         6521 t
ORIGIN      
        1 cctcgatact taatacataa ccgatcggct tcttgtcggc gggttcaccg tctttccaaa
       61 gagccagatg cgcttccaag gccttcttat cccggatcat gaccatctgg ccctcctctt
      121 ccatcgcctt ataccaagcg agttggcctt gggtctgcgc ccaagcttgt tccggagaat
      181 gccaaccggg aagtggatta tccggcccta catagcgacc gatctgggtg gcgactacta
      241 acccgacgtt tcctttacgc agttcctcaa acgatatagt ggcgtttcca cggtcgggct
      301 tatcggtcat accgatttct ctccgattga tttcttttag gggttcacgc aaatcccgat
      361 tccactccaa agcgttcatg ctaaggtcga gatgggcgtc gataataaat ggcttattca
      421 ttttattaat tgagagttga taattgataa tttgattacc gttaataggt gatgcggcgt
      481 gaacgggcaa tgataggcca ttcgccgatc gcctcacgat cccggatcac ataagccttg
      541 tcgtataaag cgaccgtagg acaaatatga acgggaatgc catagaatac ggaacctaat
      601 ggatagagcc gactgtccgg gacttccaag accagatgct cctcgctctg ggagataggt
      661 ttcgcctccg gatggttcaa gaaaaacaca cggggcaaag gactttccga ggctaccgcc
      721 ttgtaaccaa gatctacgca aacatgatgc tcatccagca cggaaatgac ccgagttatc
      781 aataaggcag ctaccttgaa cggcatatcc ggataagcgt ttccataccc ccaatcccag
      841 aacacaaacg tgccgggact gcattcgcaa tccttccgct tcgcgtacat cgggaatgta
      901 ggagtacctc ccatcacctt taccaatgga taggcaaact tgcgggatat ctcccggaac
      961 acacgttcgg tcaaggcgta cgctgcatcc gcgccttggc aacgtaccga tagctccgcg
     1021 tcatgtatat gtccgtcgta gccatgcaac ccgataatct gcagagactt cagcggcaga
     1081 atggcatcca ccagcgcctc cgctctctcc gggaggactc cggtacgatt cattcccacg
     1141 ttcagatcga taaagacatc caaggtgata ttcccggcct cgcaaagagc cgagatcgca
     1201 cgggcattct ccgcttgatc taccaagcag gagtaatggg tggcgggata tgcctttatc
     1261 aaatctaata agcgggaaat cttcggacct accggctgat aggctaataa tacatctggg
     1321 gcattcatat gccccagcat ctcggcctcg gcaatcgtag cgcacttgaa cttccggatt
     1381 ccggcatcca gcagcatgcg ggatacctca gccgccttat tcgtcttcac gtgcggacga
     1441 agccggttcg tatcgcctat gatcctcttg gccaactcga tattgccgga aatacgatcc
     1501 ggatagaacg ccaaggctgg cgagtctatc cggtctacat tacttatgac gtaccaatcg
     1561 tccatggctt attcgtataa ttcgaacaaa gcctctatct ctacaggaat attatcggga
     1621 agagaaccga atcctacggc gctacgggta cctacaccgt tatccggccc ccatacggcg
     1681 gcgaacaact cgctacagcc attgatcaca taaggatgct ttccgaaatc gggcgtacaa
     1741 tttaccatac ccaatacctt gatcactctc tttatcttgt tgaagctacc aaggttcgcc
     1801 tggatggtcg ccaacatggt aagtcctact tgctgggcgg cgagtttgcc ttcatccatc
     1861 gtcaagtcct tgccgatacg tccgatgatc aaggacttat cattccgcac aggcccgtga
     1921 ccggaaagat acaggtattt gccatctatc acacaaggct tgtaaactcc ggccggagcc
     1981 ggtgcgggag gtaaggtcaa ccctaatttc tcaaaattct catctgcgtt aatcatgctc
     2041 ataatttctt tcatttatat gttagtaaaa aaatatattg atctatttcc tgactctttc
     2101 cgttaccggt tgattcgtgg cgacagagat tccttgtagc tctacatact cgacgcttaa
     2161 aggattcttg gagctggctt taacgtagag ggattggaga atcgcctgtt ggttgttgat
     2221 cgttatgtag catacatagc gggaatcacg tttggtaatc gtcaactggc gggagggata
     2281 agcggtcaat gagcatacac aagcattatc actcgccgag atcagtttat acccataagc
     2341 cattttccgt tggatatagc tcaagccatt ggtttccccc ggatgctttt cccgattgac
     2401 ccaataaacg ttcaagggat catgtgtatc cagcttacca tccctcagat tcacatcgta
     2461 acaaaccaag ttcttattca cgcttcgtgc tatatgaaaa agcctcccga ccgttggata
     2521 agtaccttcc tccgggtccg ccgcaaacga ggcgacgaaa gggaaaagca taataacgat
     2581 actaagcagc catctctttc tcattgctca atcattcttt tattatacaa tcatatttaa
     2641 gatcattacc ccgatcaatc ctacgaccga cacgatcgtc tccatgatag accatgagca
     2701 gatcgtatcc tttatgctta ggttaaaata ttccttgaac atccagaaac cggaatcgtt
     2761 gacatgcgag aacatcaagc tacccgctcc taaagataaa accatcaagt tcgggttcgc
     2821 acccgtttgc gtaactaaag gcatcaccac gcccgccgcc gtcaacgccg ccaccgtagc
     2881 cgatcccacg cacaaacgga tcacggcaga gatcaaccaa cccaagatca acggatgaac
     2941 gggcaattgc tctaggcttg tcgccagctc attgcttacc ccgctatcct ccatgatctg
     3001 cttgaagata ccggaacccg cgatgatcaa aaggatcata gagatatctt tcacggcctc
     3061 cccatagact gccataaccg acttgatact acgtccctgc cggatgccca gcgtatatgt
     3121 agcgaacaac aaggcgatca gcattacaat ggaaggagca ccaataaaag agactatccc
     3181 gctcgccatc tcgcccatat ccttaaagca ataaggaata accgtcacga taatcagtaa
     3241 aaagacaggc aacgtagcgc tgataaaact attcgccttg cccggcatgc tatatctccc
     3301 gctatcctct ttctactcga acaacgtgac cggaccggat tttatatgtt tcaaccgact
     3361 gccgaacacc ggcccggcga taatgatagc tggaatcgcc aagaacaagc catagatcag
     3421 cgtaaggccg atatttgcgt tgaactgtac caccaaggct accggagacg gatgcggggg
     3481 caggaatcca tgcgtcacgg acaacgccgc caacatcggc aacccgatat agaccgccgg
     3541 aagcttgtat ttatacacga tcgagaagat caatggcacc aacaacacaa atccgatccc
     3601 ataaaataac ggaataccca cgacaaagcc tgtcaccatc agcccccatt gtatatgctt
     3661 agtaccaaaa agcgacacca tcacggaagc gatcttctgt gccgctccgc tctcggccac
     3721 caacttgcct agcatagcgc ctaatacgat aatcaacgtc aacccaccca agatactccc
     3781 gataccgtta ttcaccgagt ccggcagctt ctccaacgga atgcccaaag cgatgcccgc
     3841 caagatagag gagatcagaa acgcgatgaa agcatccacc ttaaagtagg atatcaagac
     3901 aatcaataag gccaaacaaa gtacgacaat gataaatgac atgttttttc gctgtattag
     3961 tttataatcc gtaaacggga tacaaagaaa acatttattt ccgaactacc cctttttacg
     4021 ataactaatt accgctaaca gattaaaaaa aacagcaaat agacagacaa tcacaaaatg
     4081 tccccgtaaa tcggcaaagc cgctcccctt taaatagacc atacgcatca cctccacgaa
     4141 ataacgcacc gggttcgcca gcgtgatctt ctgcgcccat tccggcatac tgctgatcgg
     4201 cgtgaacaat ccgcttagca aggcgaaaat gatcaagaag aaaaacgccg taagcatcgc
     4261 ttgttgctgc gtggacgaga aggaggagat cgccaagcca aatcccgtaa aagcgatcaa
     4321 atatacggcg gcgaacaaat agatcacccc gaaactcccc tccggcacca agccgtagat
     4381 cagccaagcg atgaggatcg ccaccgtcag caggacaaag cctatcaccc agaaagggat
     4441 cagcttcgac agcaggaaca gggacttggg tacgggcgag acgtttatct gctcgatcgt
     4501 ccctttctcc ttctcgctca cgatattcaa ggcggagatc gatcccccga taatcgtcag
     4561 caagaatacc atgatgccgg gaaccatata gatcttgtag ctcaagtggg gattgaacag
     4621 gttaatcgaa gccactcccc tgcccgatcc catagaggcg aaacctttct ccctattgaa
     4681 atcctgtata atcgaggaga ggtaggagct acccaagccg cccttggttc cgttcacggc
     4741 gttagcggcg atcatcacgt ccgccctgcc ctccttcccc aagtcccgct cgaaatcaga
     4801 ggggatttcc agaatgatat cggactcatt gctctccacc gaggtcagcg cctcgtcgta
     4861 acgatccgac cggtctgtca ggcggaaata tccggaggat agtaccttat ctaccaattg
     4921 catggaggtg acggaatgat cattgtccac gatgctaagg ttaatatttc gcatctcgaa
     4981 attagcggcg aaaggcaaga tgatcaactg catgatcggg atgatgaaga taatcttcgg
     5041 catgaaccgg tcccgacgga tctgcttgaa ctctttctct aacaaatatc gtaacatagc
     5101 ttataatcgt attttaaaac gtttcacact caagaatacc agcacgaccg ccatgaacga
     5161 cagtatcccg atctccttca agatcgacac ggcgggaagc cccttgatca tcacgtcctt
     5221 cacggcgatg atataccatt tggccggaac gatatgggag aaccatcgca ggatatccgg
     5281 catattctct atcgggaaca tcatgccgct caacaacatg atcggaagca tcaaggcgat
     5341 accgctgatc aacatagccg cctgctgggt atcggctacc gtggagatca gcaggcccaa
     5401 gcagagggat acgattgcgt acaggatgga cacggaaacc agcaacagca ggctgccttt
     5461 tatcggaacg tccagcagga aataggatag cagcaagatc gtagcgatat tcaccatact
     5521 cagcaatagg tatgggatcg ccttggccag aatgatgtag atgggtttca acggggagac
     5581 cagcaggact tccatcgttc ccatctcctt ctctttcacg atgccgatcg aggtcatcat
     5641 ggcgcatata aggatcaaga tcaaacccat tacgccgggc acgaagttgt aggcgccttt
     5701 catttgaggg ttgtagagca aagtggtaac cggggtcacg gctttactct caaccgccga
     5761 ctcgcctttc aactgctccg cgatgatcgc cgaacaataa gcgattagct gagtcgcctc
     5821 gttcggatcg gtagcgtccg ccaagacttg tacttgggca tcggccgtgg aagcgtattg
     5881 agggggaaag acaactatga cgtgtacctt tccttgccga aacaaggcct cggcgtcctc
     5941 atagctatcg acggtcgtat acagctcgaa gtactcgctg gcattcaagc ggtctgccat
     6001 cttcagtgtc agctcatccc ggctttggtc gaaaatagcg atcggcacac gcttgatctc
     6061 ggtcgtgatg gcatatccga acaagatgat caggatgacg ggcatgagca agaggatcat
     6121 tgtcgtgcgt gcgtccctga aaatgtgata gaactccttt ctaacaaagg atatgaattg
     6181 tttcatcgtt tattctcctc tcgttgcttt tcgagccaag gcgtggaaga cttggttcat
     6241 attcgttgtc ttaaaatccc gcttcaaggc ggagggactg tctaacgctt cgatctttcc
     6301 gtctaccatg atggagacac ggttacaata ctccgcctca tccatataat gggtggtgac
     6361 gaagatcgta atcccccggg cggcggcctc atagatcaac tcccagaact ggcggcgggt
     6421 gacgggatcg acgcctccgg taggctcatc caagaaaacg atcttgggat catggatgat
     6481 cgccacggag aaggatagct tctgtttcca ccccaagggc agggaatcga ccaaggtatt
     6541 ccgctccttt tccagcccga ggatatccag caactcatcc gttttctggg acagctgccg
     6601 tttagacaag ccgtagatac cgccgaagag acggatattc tcccatacct ttagatcgcc
     6661 gtatagggag aatttctggc tcatgtatcc gatattccgt ttgatggact cgctctcccg
     6721 gtagacatcg aaaccggcta cccgggcctc gccggatgtc ggggccgaca ggccgcagag
     6781 catacgcatg gcggtggtct tccctgcccc gtttgccccg aggaagccga atatctcgcc
     6841 cggctccacc tcgaaactga tatgatcgac ggcggtgaag nnnnnnnnnn nnnnnnnnnn
     6901 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     6961 nnnnnnnnnn nnnnnnnnnn cctaccggcg tatcgataga taggcattcc ccagaacgca
     7021 ccaaagcgat acggtcgcaa cgggaggcct catccatata aggcgtagag acaagtatcg
     7081 taatgccttg ccgtttcaga cgatccagca tatcccagaa ctcagagcgg gagacaggat
     7141 cgacccccgt cgtaggctca tccaagaaca agacatccgg acgatggatc aaggcgcaac
     7201 tcaaagccag cttctgcttc ataccaccgg acagcttccc cgcccgccga tgcttgaacg
     7261 gctctatctg actatagata tcccgtacca gatcgtagtt ctcctcgatc gtcgtattga
     7321 agaccgtagc gaagaagttc aagttttcct ctactgtcag gtcttggtag agcgagaagc
     7381 ggccgggcat atatcctacc cgccgacgga tctccttcaa gtctttcacc acctccaagc
     7441 cgcagacaga ggcggtaccg ctatcggcca gcaacaacgt ggtcaggata cggaacaggg
     7501 tggtctttcc cgccccatcc ggaccgatta acccgaacaa ctcaccagag ccgatctcca
     7561 gcgacagatc ccgcagggcc tcgacatcgc cataacgctt ggtgatatga tttatatgaa
     7621 tctcattatt catatttaat ctccccatat tgcccgatct tcagataacc atcgttgcgg
     7681 acggcgatct tgatggcata taccaaatta gcccgttcgt ccttcgtctg gatacctttc
     7741 ggggtaaact cggatttatc ggagatccac gtgatcgtac cggggtattc ccggcgatca
     7801 ttcccatagt cggcgaagac cttgagagat tgccctagtt tcaggtggga taactgatcc
     7861 gccgtcacat aggcgcggag ataaagcaag tccgtatcgg cgatcttgta aagcggtttg
     7921 cctgccgccg tcacctcccc cggctcggcg tatttcacca ataccgtacc ggtctgggga
     7981 ttgaggatac ggcttttcat cagttgatca tccaattgca tgatctggta ttgcaggcct
     8041 tccgcctcgg cgtcggcacc tcccgtcgtc ttgcttaaag aggagtattg ggcatccagt
     8101 tgtttctgga gatatttgat gttattcacg atatcgtcca gttgcttttg gttacccgct
     8161 ttcgcacgca ccaaattctc ttgtcgctgt tgctcggtct tagccgtggc gatttgttgt
     8221 tccaagacag cgatctgctt acggatatcc ggcttgcgaa tatctaccga gcgaaggctg
     8281 gcagagagtt gcatcttccg cagaaaaagc tgggtgctat ccacgtaacc cacgatggcg
     8341 ccggcatcca agcgatcgcc ctcctcgata ttcagttcca tgatcttacc gttggcttcc
     8401 gaagatacca atatctcggt tgcctcaaag gtgccggaag cgtcaaaatc attgtctgta
     8461 ttaccgcaag ccgtccatag aaggctgcat aagctgataa aaatcaaatg tctcataaat
     8521 taattgtatt tgtcatactc tatttaattc gttgtataca tataattata aatggtcatc
     8581 aagcgctgta cacggtgcgc tgcggcggtt tgccgggcca tgtcctcggc gttgatctcc
     8641 cggatcaggt ccgtgacgga aatcacgcca ttctccagct tcacctccgc tgcctgcttg
     8701 atgcttgttc tcagacggat gatatcgtca tcggcacgca tcaggtccgt cattttcttt
     8761 atctccgtgt tttgccgcaa aagttgcagg cgggtattga ataagaaggt ctcccgttgc
     8821 acatcaatct ggcgacggct tacctcgatc ttcctccggt cgttcttcag cgtgtacaac
     8881 ttccccagat tccaagaaag acggacaccg gccacataat aaggctcgaa actatcctcc
     8941 agcatgttca agcccggccg gccgtaacca ccttgtacga aagctccgat acgaggcatc
     9001 aagcccgccg ttacctgctt gttttgcgtc tcgatccatt cgctcttagc atccaaggcc
     9061 cgtaattccg gacggttgat ttgcgtgaac aatgaacgct cgggtgactc cggagtcttc
     9121 aagacgactt gatccgtcag cggtttattg ataaaggtcg ccaacatctg ccgatatacc
     9181 gtacgagacg cttttagctc aatctcattt tggcgggcat tcagcagttc cacttccata
     9241 ctttccagat ccgattgatt cgccacgcca ttgtccatca tcgccttgat acgctcgata
     9301 ttgacctgca actctttttg aagcaaagcg ttctgacgta tcaactcgtc ttgcagcagg
     9361 caaccgaagt agatttgatt cacccggtcg ttcagcgcat acaactcact ttccaattgc
     9421 tcccggttgg cggtcgcctc ggcacgggtc aaagcacggg ccgaacgtgc gctgccgcca
     9481 tcccagatcg tttggtctac ctgcgccacg acttgatact gatccttgct caagctcggg
     9541 atctcaaagc cgggaagaag cgaggaaatc ttatcaccat cgaaaggcaa cttcgtcacg
     9601 tcgctctgat agcttgcctt accgcttacc gaaagctggg gaagccaagc cttgcccaca
     9661 ttactcaagc tataacgctc cgtctgatcg atcaaaccca tttgatgaat ctgcggataa
     9721 ttcgccctcg cccactcgta acattgggtg atcgtgaccg attcctgtcc gctaaccctt
     9781 ccggtataac ccaacaggct aattaacaat aatacatata cacctctcat atactctatg
     9841 atatgtttat taaattgaac aaatccatca tctggcatcc gggaccatca gctgggttat
     9901 tacctcgacg atcaaatccc tgcgcctatc catatattcc tcaaaccgac ccatatcgtt
     9961 atccaaaaaa gccgccgcta gtggcttgcg gatcaacaac gggaagacca ctaggctcac
    10021 caaggtcgaa actaaatcta tgaccggcat cttccgtaga agccccttgt ccatctcctc
    10081 ctctatctga cgacgaagac gcaagatggg ctgtattttt ttcggatctt tcagcacggt
    10141 ctggaataaa cgttccggat ctctgtttaa ctcgcctacc acaaaattcg ggaacatcgg
    10201 gttcgcacga acaattccca tatacagatc aacgatcacc ggcattttct ccagcatcgt
    10261 actcttctca tccaaaaccc gatcgatgtt cggcaacaat gaagaaagca attgcccgaa
    10321 aatagcgtcg aacagaatct ctttcgtcct ataataataa tgtaaggccg tcctgccaat
    10381 acccacttct gccgccacgt cactcatagt agccgcctcg tacccctttc ggacaaacac
    10441 tcgcttcgcc gcttctatga tgcgaggctc catctcattc atgtctttcg cttccataat
    10501 taaatgttat tttttgtttt gtcactatcg tttgtcatta cagtttgaca tatgcgtcaa
    10561 aagtagtgta aaaaaattac atagcaagta aaacctaagt tttcttgcta tgtaatcctt
    10621 ctttttttca ttcgagagga aatacgattc ctttcgagag gaaggcggat tcccttcgaa
    10681 cccgcctttc atttctatcg gaagtaatta ttggatcgtg cgagcctcaa ctccttcggt
    10741 cgtaatctcc acgggattga tcaatccctc ctcgttgaac gtcatcttct cgatacaagt
    10801 ctcccggtgg tcacgtgtct tgaccccggc cggccggcga tggtacacga tgtagtaatc
    10861 ttccgaattc ggcacatgca tgatcgagtg gtgacccgct ccgttggcga tatcgaaatt
    10921 ttgccgcaag acctccccga tacgattgaa cgggccaaaa ggagaatcgg agatggcgta
    10981 agcgaccttg taatccggtc cggtccagcc accctcactc cacatgaagt aatatttacc
    11041 attcttctta aacataaacg ggccttccac gtaatccttg ggagttacct ctttataaat
    11101 cgttccgtcc tcaaacggta taagtccggt aaagtcttta ttcaagcgta ccatgttgca
    11161 gtgcttccaa ccaccgtaat acatataata ctcatcattg tcagcgtcgt ggaaaacaaa
    11221 ctggtcgatc ggctgcgccc cattcacgat ctcgttgatc agcggcttac ccagcaaatc
    11281 cttataaggc ccttccggac gatcgctcac ggcaacaccg atacctccga tctctccctc
    11341 gtgcacgtca ttcgccccaa agaaaagata atacttaccg tccttgttga ttactgaagg
    11401 agcccacata gcgatcttcg cccatttcac ctctgccgta tcaagaatgg cggtatgctt
    11461 ggtccaactc accaaatcct tggaagagaa gcaatcgaag aaggtttgct tctcatataa
    11521 atcactcgta gtcgggtaaa tccaataggt atccccgtaa ataattccct ccggatcggc
    11581 gtaccaaccc tcgaatacag gattaccact cttcgctacc tcttcgcttg gagcctgttt
    11641 agggcccccg caggacatca aggcaccggc catcaatacc gtgtaaaaca ggcttttctt
    11701 tccgtttatc atcaatagta gattatttat tagtaaatca aatagtatct tttaattatt
    11761 cgagttctcc atgttcttcg ccaaaccacc ttccgaggtc tccttataaa gactgggcaa
    11821 atcattacct gtctggcgca tcacctcaac cacctgatca aaacttaccc ggtgttttcc
    11881 gtcggagaag ttcgagaacg tattcgcatc aagcgcacgg gcggcggcaa aagcgtttcg
    11941 ctcgatacaa gggatttgta ccaagccaca aacaggatcg caagtcaatc ccaagtgatg
    12001 ctccaatccc atctcggcgg catactcgat ctgtgcgggc gtaccaccaa acaactgact
    12061 ggcggcagcg gcagccatag cgcaagccac gccaacctca ccttggcaac ctacctctgc
    12121 ccccgatacg gaggcattcg tacgcaccac atttccaaac aagcccgccg tagccaacgc
    12181 acgcaatata cgggaatccc ggaactcgcg cgtctccttc aaatgataaa ggaccgcagg
    12241 cattacaccg caagaaccac aagtcggagc ggtcacgatc ttcccaccgc acgcattctc
    12301 ctcagacacc gccaaggcat aggcatacac cattccccgg ctcttgatac tgctgccata
    12361 acctttcgca cggatcatat aatcggaagc cttacgacga atgcccaaac ctcccggcaa
    12421 gatgccttcc gcttccagac cacgacgaac cgcatcctgc atcacttccc atacctcagc
    12481 cagataatcc cagatagaag ggccttcgtg ctgctcaaca tattcccaat aggaatggcc
    12541 agtcttctca caccaagcct gtatctcctt gatcgtatgc atatcgtata cttgctccgt
    12601 cctcaactca ttgaaagact cgttcgccaa ggttcccccg ccgatactat atacggtcca
    12661 cgtatccagc tcctcgccac tctcattata cgactcgaac aacatcccgt tcgggtgaaa
    12721 cggcaagaaa gtcttgggtt cccaagtaat atttgtcttc gcgaccggct gtaatacctc
    12781 aagaatagct gcatccgtca tatggccttt tcccgtagcc gctaggctac catataaggt
    12841 tacgttaaaa cgaacagcgc cccggttacg ttccaagaac atttgtgccg cacgcatcgg
    12901 ccccatagta tgactgcttg aagggccatg acccatccgg tatatttgtt tgattgattc
    12961 catctttctt cgatctaagt tttcttgttt ctatacttta aggaaaatat tatgtttata
    13021 aaacgcatac aaaagtacat aaattaccga tacattgcac atggcaatga gcaccggata
    13081 ataatttcct aaatattgct gggttccgaa aaacaaggat tcgccgatac acctaaaact
    13141 taccacgtta gtgagcatat aagccagtat tgaattcatg ccatacactt tcagccaagt
    13201 cgtatacttt cgatgccctt tatagtcgat ccaataatag aacaacccca taagcaagaa
    13261 acagtaccca ctgctcacca ataccatcga actagtccac agtttcttaa taacgggaag
    13321 ctcgataccc caaagccatc cggcgataac catacccaga ccaataccga ataacatccg
    13381 taatttgagc cgctcggaat ataatttgtt ctttaggata tatccggcga acaacccagt
    13441 caacacggtt accccgaaat tcaagctgct cagtatccat gtataacgat accaagtagc
    13501 gaatatcacc tccccgttct ccaccgtcgc cccatcccgg aaacgtccca gtacggtgcg
    13561 atcgatccat tcggccaaat tactatccgg tgtgtacgaa cctcccccat agttaccgac
    13621 tgtaataaac tccatcgttc cccaaaagat taataaaaga gacgccgcta taccgatctg
    13681 tacccgtatc cttacatgca agaataacaa ggaagcaatc aaatacccca tagcgatcga
    13741 ctgcaaagta tttgaataca aataaacccg gtccgggtcc aaagccaata aattaccttg
    13801 gcacatcata ccgaagaccc aaagcagtag cacccgtttc ccgatccgcc gatataccgc
    13861 catcttatcg ggcatatcct tataacgaga caaagagaaa ggcatagaaa ctcccgccat
    13921 gaataagaat aagggcatca cgagatccca cgtagagaat ccctcccatt ccacatgcga
    13981 gaatccccac ataaaagaat taaaccaagg catatcgatc gcatgggcca gcggatgcaa
    14041 caccatctcc aacaccacta agcaaaaaag gtcgaagcca cggagtacgt ccaatgactc
    14101 caaccgattt aatttcttct tctccatccg tttattatac tttcaagaaa atacgttggc
    14161 gatataagaa atacaagaat ccccaacaaa cagcgatata tgcgatagcg ctaaccaaag
    14221 gctgggcggt ctcgggcatc aacttcgcca gccctccgaa tatagcctcg gaagtatagg
    14281 agaaacggat gaaacgctgc gccaaataga tcgtaataga gttcatgccg atcacggtaa
    14341 aaaacaaagt ccatttacgc caccccaata catctatgat atagaagaac aaagcaaaca
    14401 tccaaacgga ataagcacct actacacaga caaaagagct tgtccatagc ttcttattga
    14461 ccggaaagac caagctccat aacaagccga cgatcaacaa tacagctccc gctcctacta
    14521 aacaaagcac tttctttctg tcggtcagcc cctctttccc taacttaatc cattcaccag
    14581 tgaacatacc caacattgcc gtagcaattg cggggacggt ggagaataaa ccctccggat
    14641 caaaaacagt ctcgtgcaaa cgtccgggaa gaaacaggcg gtcaatatac cccaccaaat
    14701 ttccctcgag cgtgaacggc cccgctccac cggcgtccgg cacaggcaca aaagccatca
    14761 ccagccaata gccaaccaag ataagagccg ttatccccgc acgcgctttc caaccgaaac
    14821 ggacaaacaa caaggctgcg aacatccatc ccaacccgat acgcgccagc acactcgcac
    14881 aacgcaggtg gtcaaattca aacgacaata gcccgttata taccaatccc aagaaaacta
    14941 aggtaatccc ccgacggacg atcttcttgt aaatcgcccc ttccgtcata ccttttcctc
    15001 gttgcttctc tagtgagaac ggaaacgaga tacccgcaat aaagaggaac aatgggaaga
    15061 tcgtgtcgtg atgcgccaat ccgttccatt ccacatgttc catctgcccg gctatcgcct
    15121 gaaaaaaagg attcggaaac aatgtcgcca aagcgacaaa taaagaagca ccgcccataa
    15181 taaagagcat gtcaaaaccc ctaagggcat ccaatgattg caaccgctgg ggttgttgtt
    15241 tttgtttttc catataatct atttacattt aaagtcaaca caaatatact caaactcact
    15301 tacatacgaa tgggatttga cataaaagac gctcctaatc tttcccctcg catttagcct
    15361 ccagtttttc agcgtacgct tctttcctca tcagatatag atgaataaaa aggagttata
    15421 aagttcagaa aaccatagcg aacctcttca ttgggaaatt cgagtttata aagtttaaaa
    15481 cggggatcat actcctttat ggtcaaatat ccactctgat aaagaagggg gatcggatta
    15541 ttccgttccg cacggtattc ggtaaaggcc gaagcttgtg tctctacgcc atcaatcaag
    15601 atacgcagat caaactcgct tttctttaat aattcgacaa gaaacgtagg cgtaccggtc
    15661 tgaaaccaat aatcgccaaa ctctctcttc cgcaaggcac tcaatgcgct gaatggatta
    15721 aagacacctt ctcgactcgg atgaaaatga tacccgtcat attgccgcac cattgtctcc
    15781 acggtccctt cccttgataa ggactgcatc tgtcccaact gctctaattc cggtgttaga
    15841 ttatcgacca actccgcatg ggtaatcccg caaagggtcg catagtcata gtctaaactt
    15901 atatcattga gttggttcaa atcactgaaa acactcactt gcgcaaattt ggtaactcca
    15961 gtaagaaaaa caaaacgtaa ataacgatcc gcactcttga gcactccata aaacgctttc
    16021 atgatatgtc gatacgcctc ttgcaagggt tcgttatgaa tcgtttgcaa aagaggttta
    16081 tcatattcgt ctatcaagac tactacttgt ctgcccgttt gttcccatgc acgacgaatc
    16141 acgtaaaaaa aacgttcttc cggagctcgc aatttcatct catcgccgta atcagcctcc
    16201 cacatttcaa gatattggtt caatatagcc accagatctg cctccgactc atatttgcgt
    16261 gcgttcaaat ccaaatgcaa taccggataa acattccaat cctgctctag ctgatcgata
    16321 gccaatcctt taaacagttc ttttttccct tggaaatagg cttctaacgt agatatcaat
    16381 aaacttttcc caaaacggcg aggacgactc agaaagtaag gcttaccttt cgtcaccaat
    16441 tggtaaatca aggcagtctt atccacatat aaatagttct cattccgaat attttcgaaa
    16501 ctctgtattc ctatcggtaa tttacgcata gtcgtcataa ccttttttct tactacacct
    16561 gttgtcgaac aaagatagaa cttttttccg gaacaagtct ccgattttag ctttcactct
    16621 atgaaatact caattttttc tacactaata gagggcgata ttttactttc cataagctgg
    16681 aagtagaata tcgccctcta ttttacaaga cagtttgtct atgagtaagc actagatcta
    16741 aggcatacaa atatttcact gagtaagatc acctcatagc cttagcaaaa gctctaatcg
    16801 cataatgaat aaaataataa acagccttat acaccggcaa atccatctca tttctcaaaa
    16861 tgttccactg ccaacgcatg gcttttaatt tattcgaaga gaccgaatgg tcactaactc
    16921 ggtaaagagc cgtcaccgta tttgtgttct gcgctttata cccttgcttt aagatagaaa
    16981 gccaacatac ataatcctca tgcccaattt ccttgaaaaa tatctttccc gtcaaggctg
    17041 aatcatacat ggctgtcaag catcctatac aattcccttt caataacaaa ggataatcaa
    17101 cctcacaagg agctattacc tcacgcccgc atcgctctcc gcctagactt actttctcat
    17161 agttagagaa aacaatagcg acctcggatt tctcgaagac ttttaactga tcgcttagct
    17221 tattcggtaa ccatatatca tcgctatcca agaaagcaat ataccgtcct ttcgcttcct
    17281 ttattcccat attacggggt aacgtaggcg aaccggatgg tttatccgtc cgtaaatatc
    17341 gaatacggga atctattctc gcatactctt gaatgattga gagcgaatca tcactagaac
    17401 aatcatccac aataatcatc tcccaatccc caaacgattg agccaatacg gactcaatcg
    17461 cttgggatat aaaaggagcc gcattataac acggggttat aatggataca agaggcaaca
    17521 cgttaaaata caaatgatta tttaaataaa taacgtttca acttagcgaa tgccttaagc
    17581 gaacgtttca agtctgaagg attacgcaaa ccgactctca gcctgtgtaa aatgtaactg
    17641 gcacgtaaat aatatttctt ccgtgcccta ttacagaaat caaccatttc ccctgcggaa
    17701 agatccggta aagacaatac ggtgttatgt gtaccatccg gcaaacaata cttctcataa
    17761 tccgtctcta tatagttatt ttccctcgcc cactgataag cctccgtacc gggataaggt
    17821 atcaacggga aaaactgggc ggtatccgta ttcaacctta acgctaaccg aagagtctct
    17881 tccatggttt cccgggtttc gccttggtta ccgaccatat aacaagcatg tattaacaaa
    17941 cccgcctttt tagcgttggc aacatactga tagaaatatt ccaccttcgt tcctttcttg
    18001 atgttatcca atatctgttg gctaccactc tctatacccg gaataatcaa acgacatccg
    18061 gcctttttca tagccaacat cgtttccaaa tcaaggtcta cacgagcatt acataaccat
    18121 ttcagccgtt tattcaattt cttttccact aacaaacgac aaatgtccaa tactcgcttc
    18181 ttattggctg taaatgtatc atcttcgatt actacctctt tcacatctgg gaaattagcg
    18241 gcaatgtatt cgaactcggc caccacattc tctgcggatc gtgcccgaaa agcatgccca
    18301 tgcatcgttt gcggatagac acagaaatta caacgaaagg gacatccacg cccggtaaat
    18361 atctggatag agggatatgt ggcagcagcg aaaaagtaat ccctctcatt taaatgttcc
    18421 ttgataaatt gtgaggcaaa aggaagatca tccaaattct tcatcggtgg cataggcgca
    18481 gttcgtacaa actccttccc gtcccaaaaa caaagccctc gaacctcccg cagatccttt
    18541 cctgcgtcca gaacattcgc tagctcattc acgatacaat catattcccc aatagcgacc
    18601 gcatccaccg cattcgaata acccaacgtc tcttctgcgc aagccgaagg atgagtcccc
    18661 acaagcacga caaacgagtg aggatacaat gccttcagct tcccggcaaa agcaacgtca
    18721 cttttaatgg aaggcgtact tgtatctaaa acaaacaatg aatgctcatt atccgtcttc
    18781 cgaataatgt ttaaagactg ttcctcattt aactgtttag ctggagcatc caaaaaagag
    18841 acattatgtc cctgtttgct tgaatacaaa gccgcataaa tcagccatag aggataatat
    18901 aaagccccac ttttcgtaat tgccggacta cgggactcac gagagaattt tccatactca
    18961 gctttgaaag ggggattaat gaaatagatg ttcatgattt atcaagttta cttattaagt
    19021 atataatctt atcctttgga atccatggat aatgaaatca gcaagtcata tattttcttg
    19081 ccctgcttcg tattatcgta tcgctcccga aaagtgctcg ctatttccga taatctgtca
    19141 agagatatcg ggttcgtcaa caagcgttct atctcattcg ccatcgcctt gtcgtccgta
    19201 gccggctcat aataattcaa gagccccatc gtcgtctcga acaaagccgt ttccttattc
    19261 gtcaataccg gtgtaccata gatagccgcc tcgatagggg tatatccgaa tccctccatc
    19321 aaggacggat ggataaacaa atccgcttga ttgtaatact gagccaaagt ctcgtcagaa
    19381 acaggtttcg ttacatggta aatccgggat gaaaggtttt cttcttggat aaaaggtaac
    19441 gctttctcgg tccagacggg ccttgtcttt ccgatgatca ccaaggtgtg aggaatttta
    19501 tcttttaggc gattaaacgc tctcagtaag gtcatcacat tcttgtgttc catcaaggaa
    19561 ctgacgtaca gtaaatattt ccctttaaca ggaagcgtat cccgtttttg gggaagttga
    19621 tcgactacaa ccccgttata gatggtattt agctttcggg gagaaatgaa cggataagtc
    19681 ttgcgcacgt cctctctcac gaagtcggaa atgacaatcg aagccttgca tctccataag
    19741 gccaagggat aaaagaaacg gcaagcccat aagcgaagcc ctttatagat tcgtaacccc
    19801 tgtaaatcat ggagaacaag aaccgtctta tcccgtctgt gaaaacagaa gttcggggga
    19861 aatacatgag gaacaaaaag aacatcatgt tctatgttct ttacagtgtt cttccaatgt
    19921 cggaaattcc gcaaaagagt cataggattc ctccccgtat caaaagcgat ttccaaacaa
    19981 ggatattccg gaaacgtgac gtgcacatga tcgtatatcc gggcatcaca gagaatcgag
    20041 atatctttat agccgttttc tttaaatccg gccaatatac gtaaaccgta tacggtaatc
    20101 gcgttgtacg gttgattgca accggacagg tcaaacaata tattcatatg attggattaa
    20161 ctagaaatgg aacggtatca gttttccgtc tggaattgat aacactgaat atacctgtat
    20221 caagacatat ccaaacaaga gatatgctat gatcaaacgg ttctctttac gtgagggcaa
    20281 actgggtaaa cctgccaagg tcatacattc tacaaaccga tagttcaagg agaggcgagt
    20341 agccacgatt tctatctgcc caaacaatag ataaatagcc atattaaata atgcgctcca
    20401 aagaaagata ttctttagtc gatcatcgat cttcatccga ggtacagcgt aaacgattaa
    20461 ccccgtgatc atgactcgat gaaccgtact aaaagaataa agaatatttc cattgtaaaa
    20521 gtcatccata ctataatcca tgaccttttt caccgcatac agatctcctc caatcttgct
    20581 tattaaagga tctaagacat cgacaaacag caagacaaca taaatgaaca ggaatatgag
    20641 ctgtatacct tgcgtacaag gtctgcccac aaaaaacgca aaaggaagga ataccaaagc
    20701 cgaattatga accgatatgg ctaaccctat aaatatccaa taaaagaaca tcttcccctt
    20761 ccatgcgtga taaacggcta caccaataaa tcccaacgca agtccctgac ggataccatt
    20821 catctcataa gacaagaacc agaaacccaa gtaaatcatc aaagacaaat atggattggg
    20881 ggacatctta cgaaacacat agtatttcgt aaagaaggac aaggaaaaca ccaatacgat
    20941 cagatgaaaa tagtctcctc cgaaccactt aatgatccgg ataagttcag agaatcccgc
    21001 ctccatggtt tcgtccccat gcaggaaaat acgtaaatag gcatagtaat cggctccgac
    21061 accctcgccc cgtaatgcgc caacgacaaa acaaagcaat agcagaatga cgacaagagg
    21121 ggtacaccgc cttttgttaa gacgaataaa cgctatgacg aaagataata tgggaagcgt
    21181 ataataaatc atcacatgga tacaggaaat gtaacaaagc ccattatacg gcctcgcaac
    21241 gtataataat aatacttcgt atgccgactc agcaagcaac cgccgaccga acgaagtaca
    21301 taataaataa acctaaacag gaaagcgtaa tgtttacgtc ctaccacctc tttcttgaac
    21361 aaggctccga atcccaaccc ataagcatag gccttaggga tgttaacgaa tacatccgct
    21421 atatatggat gattaatata agtgtcccgc agaaatatcc cgacatcttt ttcatcaagg
    21481 atctcccaca ggtagtcgct ttcctcacca gatccccaat aggcacctac acccaaacgg
    21541 acatcgaaac gagcctccgt ctttcggaca aaaatattat ttgaaaaaca atatcttaat
    21601 gtcttgttac gtgaaattag ctctctctcc gaaaccttcc aaacccttcc atcaaaagcg
    21661 tccttgacag ccgtggcgac aagaacaata tccttttgcc gctggaaaac atcgatgacc
    21721 ttctccaaga catcctcctc gtaaaagcaa tcatcatcag ggaaagcgac gatctctccc
    21781 cggctataat ccagaccgat atttcggttc agggaaagcc cttttgcctc gcttcggata
    21841 tattggatcg ttaagcggga agcgtactcc gcgaccatct cccgcaatat gaaatgcgga
    21901 ttctggtcga ccaatataaa ctcaaagtct ttgtagctct gcctcgcgag agaacccaat
    21961 aacgttcgta cttcttccgt gcgcccatag gtcgcggtaa ttaaagatat cattacgtcg
    22021 taaaattaag tgtatgattc attccgttcc cttacccgtt taagtgactc agtaatcttt
    22081 taagagcctc cactccgaac aagaatactc tatttatata tctataaccc atcgttgtcc
    22141 tgagagtaaa atagacggat cctctacgcc aattaactgt atgtcgcttc aattccatag
    22201 gcgacaatct ttttacgata taggcgtagt ggcccttttt gctatttacc cttatcgcac
    22261 gtagggcttt caaataagaa tatacaggtc gttggctgaa ataagcgagc gattgggtcg
    22321 caagcgcaag tgttgcgggt aaatgcaggt ataaataatt cctcatgaat aaacgggtaa
    22381 acaaagcgac ggtctcctcg tgacaggtca tgagatcccg tgtatcgccc tccttttctc
    22441 cattttcaaa tacgggccgt actcgcccgt catcttcaag ataagcgatc gtccgcttat
    22501 gtggagaaac ggaaaaatac tgttcgagaa tactacccaa ctcatcactg atgtatcgta
    22561 aagacgaact gaggcgcata cgctccgcgt aatataaggc atggtagtct cctgcctcct
    22621 ggatcggttt ccgttcatcc accacctcca gataataccc ttccgctggc ctgaatcccc
    22681 cttgtctcaa aatagcgttt atcgcttgtt ggcaagaacg tgtaccccgg atatctacca
    22741 cgaccgtctt gtgaatcgga tccgccaatc cctcttgtat gaagtatctc aaaataaggt
    22801 ctctttgcgt gtcatgataa cgagacaata tcgccaacac ctccggattg gcgaacagct
    22861 cttctccttt tccgcttcca cttccacttc gcatgacgca ttccacctca tgccatgtct
    22921 ctgaggtgat gaagttccct aatatgtcaa gctcagtttc atccgtaaaa ccgaacattg
    22981 tctttctcaa agacaacagg ctatccggag tgatcgctgg caacccgggt aaatacaagg
    23041 atgagcggga tacataaaga tacttcatac gcaagccggg aaattcacct tccaactctt
    23101 tcgctatccg ataaaggata tagccatcac gtgcgaggaa aaagaggctt ctgatccccc
    23161 tgctgacggc atctcgcaag acatgataaa cgaaggccac atatagcggg gctatcaagt
    23221 ccgcagcgaa agcgtaacgc ggctcgtcag gaaacgcaag ccgtacggcc ctcgataaac
    23281 cagccaggtg ctggttgacg aaaaagccgg ggaaataatc ctgccgtacc aagaaacgct
    23341 catatacgga atacacatga tgaataagcg aggccttgat ccccatacga cgcggtatgc
    23401 gataatcgct atgccggtta tctccccaat gataccaatc cttgaagcgt agtccgtttt
    23461 ctgccgctat atgcttatac aggtttcccg tatgcttggt tttcccacaa gccgaggaga
    23521 catatagctt atccccttcc cgccaaaagc catgctcgat cagcaattcc gacaagaacg
    23581 ttcgcggcag atacatatct gagatataat aaacgctatg cccttcccga tgcagcgttt
    23641 ttatcttctc ccggatggca tacacgggaa ccaattgctc ccgctctacc tgcatctcca
    23701 aacgtgcgat ctcagtcttt gattgggcgg tcaacgccat gaagtcacaa caaacgtaaa
    23761 tagcctccag cgttatttcc tctacctgag acaaggcacg ggctttccgc tcccctttaa
    23821 cccgttccaa cgcaaaatca gcccgtgcgc tctcgtcgct attcgctcca agaacacgat
    23881 aagccagaag atcaaatacg ttacgagggg caccgcaagc ccggataaag caggtgtcga
    23941 atagatcgaa tgaataaatc acacgtgtat tccttttcat aaatcaatgc gtgatggtat
    24001 aaatcatata tcaaagagat tgttattttc tctttttgat catgtcaatc aagtagtgta
    24061 tttcctcgga ccgagttaat aaggagatac ccgtatagag gacacatcca agtggtacgc
    24121 ccaaggcgat ccgcaaaata tccgaatcaa ctgcgtagtt caatagatag acgacaccac
    24181 ccatcgacag agcccgcaac aagataggta ccaagacacg catctcgttt ttgaacgtaa
    24241 tagccggaag gagtcttcgg gtgtatagcg taatgacata caaatcaatg atacaataaa
    24301 tcacccaacc tacgcagagc actaccagcc ccatgaagag ggtggagaac aagatggtaa
    24361 acgcaatgat cttcttgaag atctccgact tcatgtaata atcactccta tgcttcacgt
    24421 tcaatatctg ccagttcaaa ccggaaagag gttgccagat ccatccaaaa cagagtattt
    24481 ggatcaaagg gaccacatcc agccatttct ccatcaacag caatctcact aacggttcgg
    24541 ctaacgcggc gagtcccgtc atcagcggaa aaacaatgaa ggcattgaga cggacaaacc
    24601 gataaaaggt atgccgtaac gcctcgttgt cgttctgcaa ctcacactca ataggatagg
    24661 ccacgcgaga aagcgtctca tcgatcgaat taggtagtaa gctcgtcatc tggaccgcct
    24721 gactatataa tcccgtcaag gccggtgagt aaaacttacc gaccaacaaa taactcccat
    24781 tcatatacaa cgtatgcaag actcgtgtta tcaggatttt cgagccaaac ttaaagaaat
    24841 accggaacga gcggcgggag aacacgagcg agggcatcca gcccgccgat acccaaagta
    24901 acgccacgtt gagcaggttt tgcagcaagg cctgccagac caacgtccac accccgaatc
    24961 cccgataggc catccagaca cccgtcccgc cgctcaccga gatggctact aacgagatcc
    25021 acgcctgccg atggaaatcc attgcgatgt tcagtttcgc ctgttgcacc gtccggaacg
    25081 agttgatcac gaagatcaag cccatccata ccgtcagctc ctccagtaac ggctccccat
    25141 agaacccagc gatcagcgga gacagtaaga acaacacgcc atagatcgcc gccgccactc
    25201 cgatgttgaa ccagaaggtg gtcgagaaat ccacctccgt ccgatcccgt ttctggatca
    25261 gagcttccac gaagccggag tccacgaaga tctgcgccac cacgagaaag atcgtcagca
    25321 tcgccaccag cccatagtcg gccggcgaca actgcctagc gatcaatatg gagaaaaaga
    25381 ccatgaggcc ctggcgggcg aacttctcaa ccgcactcca tgcaacacct cgtatcgcct
    25441 tattttttat ggattccgac atatattatg ttttgacaat taatagaatt ctaaaagcaa
    25501 gcatccaacc cctatggcca tacctcttag ccccagtgtt cactgggggt tgagaagtac
    25561 cataagattg gattaatttg taaattattt gattttaaca caaaatttct tgtgtcatga
    25621 gttcataatc ccttcgacct tccgcaatca aactgtcaat tcatttaaaa cagatatttc
    25681 tcttttaaaa cgctattaac catagcttta gatcctcgca tgaagttgta ttgggcttgc
    25741 aacacgcaaa agcaagacac cggcacgtca tccaaagtta aacttccagc cgaagccagt
    25801 aacaagatct tgtctgtctt gttgtcggtg gtcaccgaat tgtcgatgag ccagcctttc
    25861 aatactttct tcatggtatt ttgacttaaa ggggggcgaa atcaccattc cctgctttct
    25921 ttgtctagaa tttcttcccg aacgcaatgt tcaagaacgt cttcaccaat atcttgaaat
    25981 cgaaccacca cgagcggtgc tccagataga acaagtcata gcgtaagcgg cgaagcatct
    26041 tctccagcgt atccgtatag ccgttgtaga gcgtggcgta agaggtcact cccggacgga
    26101 tctggtacaa aaaacgatag cggggatcat gttccatgat ctggtcgata tagaacttcc
    26161 gttccggacg ggggccgatg aaagccatat caccgatgaa gacattccat aattggggaa
    26221 gctcgtccaa atgatgctcg cgcaggaact tgcccacatg cgtcatacgg ggatcagcgc
    26281 ctcccttgta aagggcgggg ccgaacttct ctgcgtccaa acgcatgctg cggaacttat
    26341 agatatgaaa cggacggccg aaacggccaa tccgctcctg cctgaaaatg gcagggccgc
    26401 catcctcgcg cctcacggcg atgtagcaga tcaagaacaa gggggagaat acgaccaagg
    26461 cgataaaggc caaaagacaa tcccctatac gcttcacgtt acgctcgaag gcggtcatcc
    26521 catccgggat aaaatcagta gatttatcaa cactctcttt tataagcatg gcttgtttgt
    26581 ctgtctataa aggcgggcac gaagtcaaaa acgaatctca ttcgcatagc ccacccttaa
    26641 tttatttctt tcctctattt ttctcctcct ctttcttgta atcgatatac cgctccaagg
    26701 cctcacgtgc cagacggcgg aaaagttcct cgtccgacag atggtcccaa aggagatcta
    26761 ccaa
//
LOCUS       DBMDTB010000054        26366 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_659_length_26366_cov_10.966571, whole genome shotgun sequence.
ACCESSION   DBMDTB010000054 DBMDTB010000000
VERSION     DBMDTB010000054.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 26366)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 26366)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26366
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_659_length_26366_cov_10.966571"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(91..3204)
                     /locus_tag="ACZPB4_09925"
     CDS             complement(91..3204)
                     /locus_tag="ACZPB4_09925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HIR1098566.1"
                     /translation="MKRIIYLAIHRRGLMFVLFLFLAIVGYYSWTRLAIDAYPDIADT
                     TVQVVTQVPGLAAEEIEQQISIPIERAMNGLPGLNVMRSKNTFGLSTVVLVFDDGIED
                     YWARQRVQERLVDVELPYNAVPGLNPLTSPTGEIFRYVVESDRLDLRELTDLHKWVII
                     PRLKQVTGVADVSNYGGITTQYQIEVNPYKMEQYDITLGDITEKIEKNNVNAGGSMLS
                     RGDLSYVIRGIGLVKDLEDLGHIVIKTVNGVPVYLNDIGKLKYGNLERKGVLGFTDDT
                     RDYSDGVEGIVQMLRGENPSRVLDDVHKAVDELNNETLPEGTRIHPFMDRTDLVNTTL
                     HTVSHTLFEGMVLVVLVLILFLGSWRGALLVALTIPLSLLIAFILMHVTNIPANLLSL
                     GAIDFGILVDGAIVMMETVLKKRERHPDEVLTEDSILRRTTEVARPIFFSTLIIITAY
                     LPLFAFEHIEKKLFTPMAYTVGYALLGALCVALFLIPGLAFYAYRKPGKIYHNRWLEK
                     LSTAYHSQIVRLMEKPRRVIVPLLAILLGAGILSYTVGKDFLPPLDEGAIWIQVQLPP
                     GISIEKSKEMGAELRKTLKEFKEVSYVMTQVGRDDEGAEAFSLSHVECGVGLKPYSTW
                     KFGKTKADLIEEMAAKLETMPGYSVGFSQPIIDMVMDQIAGAHSDLALKIYSDDITES
                     RHIADQVANVLKEIPGAADVAVDQEPPLPQLQIIADRARIAQYGLNVSDVADLIELAI
                     GGASISQIFVGSKSYDVICRFDDASRNSPERIGNLLLTTGSGTKIPLSQVAEIKMTTG
                     ASTITREMNKRHLTVRVNLRGVDLTAFLNKANALIDKEVKYDHDSVHLKWAGQFENQH
                     RAYARLGAVVPLALGLMLLLLFAACGKFRQAALMMSVVPLALFGGMLALNVRGMTLNV
                     SSAVGFIALVGVAIQNGVIMISHINNLRTRERDLKDAVITGTKHRFRPILMTATVAVL
                     GLLPASVSTGIGSDVQRPLATVIVYGLLFATVITLYVLPALYYMIEKHYEGKDLTPVS
                     EEKELHA"
     gene            complement(3211..4320)
                     /locus_tag="ACZPB4_09930"
     CDS             complement(3211..4320)
                     /locus_tag="ACZPB4_09930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HIR1098567.1"
                     /translation="MKSIFLLLLPAIVLCSCHTQKQEDESAHAVTLKGDIIHIGSESP
                     VLSKLTKETVKREPYRMEFTTSGVVQAIPSNYAEVASPVSGRITKSFVRLGQKVAPGS
                     PIFEISAPAVYEAGKSYYQARQEMELALKSLNREKDLMKNKVGVQKELEEAEVNYELK
                     KKDYENMVAALKVFQINPDEMALGQPLIVRSPIAGEVVKDQIVIGQYMKEDAEPVAVI
                     ADLSKVWVVAHVKEKDLSLIQALDEVEIRLVAMPDKPISGKIYHISEMLDPDTRSVEV
                     LIECDNSTRLMKPEMYGTVKLSDREAEVIRIPTSAILQEEENMYVLVELGNNDYRKQK
                     IETGHTEDGKTVVLSGLNVGDEIVVTGAFYLLDAR"
     gene            complement(4369..4728)
                     /locus_tag="ACZPB4_09935"
     CDS             complement(4369..4728)
                     /locus_tag="ACZPB4_09935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098568.1"
                     /translation="MKTMRSLKWLRPLLVVLFMSYYVGGTAFTHTHHFLNYSITHSHP
                     YLPGADGLPHHEHSTVAFNTIEELTELCMELIPYLPLVMAWALLMVVLVFLKKEVVLR
                     LVRRGESRAPPSFGIVI"
     gene            4857..6404
                     /locus_tag="ACZPB4_09940"
     CDS             4857..6404
                     /locus_tag="ACZPB4_09940"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008235 - metalloexopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M28 family metallopeptidase"
                     /protein_id="HIR1098569.1"
                     /translation="MRKILLVCAALACMTVSPVPAQDAAVKKIIEMGQNDNQVMHQLD
                     ILTNRFGGRLIGSDAYENAAEWMVREFKSWGLDVQLEEAGTVPVGFNRGPWFGRLLSD
                     NGMILHFATPSYTSGTKGVQRGHAVMEPRNDEEFQQIKGRLNGAWVLISGKNVGWPID
                     RSASGDSIRVEIKKENNEIMKKNNDLRRRNWENGEKNEMLPYKEFPGLYYKEMCEAGA
                     LGFIQSSTVPIRALYDRKMMNDPNTNFDNLPELPDIKLDEHQFAIIEQMVKERRTFEL
                     EFDIRNHFKLGPVKYHNVVASIKGSKYPDEYVIISGHLDAFDVATGGIDCGTGIGPMM
                     EAARMIAKSGAKPKRTILFIGFAGEEFGLLGAQAWVKAHKDKLPKIANLFNRDGGPEP
                     PVGISVPQAMYDDFVKISEPIQKIRPDYPFEVKVREPRKRPTRMGGTDASVFAIEGVP
                     TLGFTTEDFKGYDFDYGEIWHTERDLYTKNIPEYQEHTATVTAIIALGVANLDKQLSR
                     EGLYTEE"
     gene            complement(6546..6619)
                     /locus_tag="ACZPB4_09945"
     tRNA            complement(6546..6619)
                     /locus_tag="ACZPB4_09945"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6583..6585),aa:His,seq:gtg)
     gene            complement(6712..6785)
                     /locus_tag="ACZPB4_09950"
     tRNA            complement(6712..6785)
                     /locus_tag="ACZPB4_09950"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6749..6751),aa:His,seq:gtg)
     gene            complement(6884..7780)
                     /gene="folD"
                     /locus_tag="ACZPB4_09955"
     CDS             complement(6884..7780)
                     /gene="folD"
                     /locus_tag="ACZPB4_09955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase
                     FolD"
                     /protein_id="HIR1098570.1"
                     /translation="MEEQHYQLLDGKAVSAQMKKEMAEEVAQIKAAGGKIPHLAAILV
                     GHDGGSETYVASKVKTCQEIGFKSTLIRFEEDVTEEELLRKVDELNNDPDVDGFIVQL
                     PLPKHISEQKVIEAIDYRKDVDGFHPINVGRMSIGLPCFVSATPAGILELLKRYHIET
                     QGKHCVVLGRSNIVGKPMATLMMQKSYPGDCTVTVCHSRSKNLKEMCLSADIIIVALG
                     VPEFLKGNMVKEGAVIVDVGTTRMPSSITKSGFKLTGDVLFNEVAPKCSYITPVPGGV
                     GPMTIISLMRNTLLAGKKAIYK"
     gene            complement(7803..9140)
                     /gene="ffh"
                     /locus_tag="ACZPB4_09960"
     CDS             complement(7803..9140)
                     /gene="ffh"
                     /locus_tag="ACZPB4_09960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005048 - signal sequence binding
                     [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HIR1098571.1"
                     /translation="MFENLSERLDRSFKLLKGEGKITEINVAETLKDVRKALLDADVN
                     YKVAKSFTDTVKEKALGQNVLTSVKPSQLMVKIVHDELASLMGGTAVDVNLQGNPAII
                     LMSGLQGSGKTTFTGKLASLLKTKKNKKPLLAACDVYRPAAIEQLRVVGEQVGVPVYM
                     ELENKNPVEIAMNAIREARAKGNDVVIVDTAGRLAIDEQMMNEIAAIKSAIQPDETLF
                     VVDAMTGQDAVNTAREFNERLNFDGVVLTKLDGDTRGGAALSIRTVVDKPIKFVGTGE
                     KMDALDIFHPERMADRILGMGDIVSLVERAQEQYDEEEAKRLQKKIAKNQFDFNDFIS
                     QIQQIKKMGNLKELASMIPGVGKALKDVDIDDNAFKSIEAIIYSMTPDERSNPAILNG
                     SRRQRIAKGSGTSIQEVNKLIKQFDETRKMMRMLTSAKSGKMKLPSMKPSFRR"
     gene            complement(9242..11152)
                     /locus_tag="ACZPB4_09965"
     CDS             complement(9242..11152)
                     /locus_tag="ACZPB4_09965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HIR1098572.1"
                     /translation="MSTTCGCEHCHSHGSSGLWMPTISFVLLVIGLIGKYSGISWFAE
                     SWIEAIWFLVAFLPVGLPVMREAWEAALRKDFFSEFSLMAIASIGAFCIGEYPEAVAV
                     MLFYTVGERLQLLAVNKASKNISDLLDVRPERTDVWRTGTYMNVSPKDVKVGERIEVK
                     PGGRVPLDGVLLEAEAQFDTSALTGESMPRSIREGEEVLAGMIVQGQAVRIQVNRPYE
                     QSALARILALVKDASERKAPAELFIRRFARIYTPIVILLSFLIVSVPALVGMVTPSFQ
                     YVFSDWLYRGLVFLVISCPCALVISVPLGYFGGIGAASRAGILFKGGNYLDAITRVNT
                     VAFDKTGTLTTGRFEVTMVESTGIPASDLLSVLLSVERKSTHPVAQAVVRYAEKQDSV
                     PMEITDMRELAGHGVEAIVNGRQVLVGNIRLLAERDIPVPKELSDSVSTVVVSTIDGK
                     YAGHLLLSDTLKKDAVDAIRRLKDLDVKDIRLLSGDKQEIVNQFAERLGVDKAYGNLL
                     PEDKAAYIERLTAETDKSVAFVGDGMNDAPVLALSDVGIAMGGLGSDAAIESADVVIQ
                     TDQPSKVAEAISIGRATRNIVRQNIVGSIGVKVIVLVAGAFGFATLWEAVFADVGVSL
                     LAVLNSIRILKR"
     gene            complement(11242..11670)
                     /locus_tag="ACZPB4_09970"
     CDS             complement(11242..11670)
                     /locus_tag="ACZPB4_09970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HIR1098573.1"
                     /translation="MSTKQCEDMLVGKGVRPTAARILVLQKLSERTSPASLFELEAEL
                     ETLDKSTISRSLALLLEHHAIHSFEDGSGSIKYEICQSRSETCPVGDRHIHFFCEVCR
                     KTSCLNNIKIPVAQLPEGYIMDTINYTVKGVCPLCNKRRS"
     gene            complement(11769..13091)
                     /locus_tag="ACZPB4_09975"
     CDS             complement(11769..13091)
                     /locus_tag="ACZPB4_09975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005681581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HIR1098574.1"
                     /translation="MYTNRNIWNVSYPIFLSLLAQNVINVTDTAFLGRVGEVELGASA
                     MGGLYYICAFTIAFGFSTGSQIVIGRRNGEGRYDQIGPVMIQGVFFLLSLAAILFLFS
                     RFFAGDVMRVLISSDAILNATEEFLNWRVFGFFFSFVNVMFRALFIGITRTKVLTLNA
                     VLMAMTNVLLDYLLIFGHAGFPKMGIQGAAIASVIAEAVSILFFVVYTRLTVDIRKYA
                     LNQIRSFDFGLLKRVLDISVFTMLQYFLSIATWFMFFIAVEHLGQRELAVANIVRSIY
                     VVMLIPVNSLATTTNTFVSNSIGAGAINQVIPTIWKICKLSLGIMVVFAAIVSLMPGW
                     VVSVYTNDASLVAASVPSVYVIVGSLLIGSVANVAFNGVSGTGNTRSALFMEAAVLIL
                     YVLFVYVAGMRLRLPVAVCFLTEAIYYSGLLVASVIYLKKASWQNKRI"
     gene            complement(13190..13540)
                     /gene="panD"
                     /locus_tag="ACZPB4_09980"
     CDS             complement(13190..13540)
                     /gene="panD"
                     /locus_tag="ACZPB4_09980"
                     /EC_number="4.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004068 - aspartate 1-decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0006523 - alanine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 1-decarboxylase"
                     /protein_id="HIR1098575.1"
                     /translation="MFIEVVKSKIHRVTVTEANLNYIGSITIDEDLLDAANLIANEKV
                     SIVNNNNGERFETYIIKGERGSGVVCLNGAAARKAQPGDIIIVMSYAMMDFEEAKTFK
                     PSVVFPDTATNKLI"
     gene            complement(13554..14393)
                     /gene="panC"
                     /locus_tag="ACZPB4_09985"
     CDS             complement(13554..14393)
                     /gene="panC"
                     /locus_tag="ACZPB4_09985"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005646584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004592 - pantoate-beta-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HIR1098576.1"
                     /translation="MKIVNSIKDLKAYLAEAKQDNKKIGFVPTMGALHNGHLSLVQHC
                     VKNNDVCVVSVFVNPTQFNDKHDLETYPRTLEADCVLLESAGCDYVFAPSVEEMYPEP
                     DTRTFDLGTVSEVMEGAKRPGHFNGVAQVVSKLFYIVEPDNAYFGEKDFQQIAVIRAM
                     VKQLNIPVTINACPIVREGDGLALSSRNTRLTPEQRQKAPLIARTLKESTTFVPGKSV
                     QEVIDYVVNTINSDPVMEVEYYEIVDGNTLESIKNWSDTDYPVGCITVYCGEVRLIDN
                     IKY"
     gene            14494..15318
                     /locus_tag="ACZPB4_09990"
     CDS             14494..15318
                     /locus_tag="ACZPB4_09990"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004373 - alpha-1,4-glucan
                     glucosyltransferase (UDP-glucose donor) activity [Evidence
                     IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch synthase"
                     /protein_id="HIR1098577.1"
                     /translation="MDAKKILFIAQEITPYLPESEIATICRNLPQGIQERGREIRTFM
                     PKFGNINERRNQLHEVIRLSGMNLIIDDTDHPLIIKVASIQSARMQVYFIDNEDFFQR
                     KSTVSDENGNEYEDNDDRSIFYVRGVLETVKKLRWIPDVIHCHGWMSALTALYIKRMY
                     ADDPCLRNAKIVYSIYNDDFKNPLNKDFATKLKADGAKEADLKLIKADTSFVGLTKLA
                     IDFADGVIQGSETINQEVLDYISAKKDTPFLPYQSPETYMDEFNKFYDVVLDSNTK"
     gene            15330..16706
                     /locus_tag="ACZPB4_09995"
     CDS             15330..16706
                     /locus_tag="ACZPB4_09995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4270 domain-containing protein"
                     /protein_id="HIR1098578.1"
                     /translation="MKIKLLILGLGLGASILAGCNDDFSSIGTSIQPGDDTIAVYMDT
                     FQIQATTVQLDSIYARSTSAQLGELYDPLYGNLVSDYMCQFYCPSDFQFKHTPYEGKI
                     DSVEFNIYYNGSNKNGVWVGDSLAPMRAEIFKITSPLQKNFYTNIDPKQYCNMQESMG
                     AQAYTAYNTSISDSLRNSDGYSPHVSIKMPTEFGQKFYDETINNPGTFKNQETFNEFF
                     PGLYVTTTFGSGNILSVASSVLKIYYNYAVKSTAGKDSLITTWEAFSVTKEVIQLSRF
                     KNTDMSQLLQPNDSYAFFKTPAGVCTRIVLPTQEITPIMEKRIVNNLPLELKAMPQED
                     WQYALAPPPYLLILPEDSVKSFFEGSQIDNNVTSFLSKAYDATTRTYSFPNLANLLKY
                     QMENNPDKDLSLLLIPVQRTTTTGNSYGQSTVVTTAITNYLAPSGVKIRKDEEVMKIG
                     ITSCKYVR"
     gene            complement(16846..18138)
                     /locus_tag="ACZPB4_10000"
     CDS             complement(16846..18138)
                     /locus_tag="ACZPB4_10000"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 57 protein"
                     /protein_id="HIR1098579.1"
                     /translation="MKTICFYFQIHQPFRLKRYRFFDIGNDHYYYDDFQNEEIIHRIA
                     EQCYLPANRTILEMIKTSGGKFKVAFSISGVALEQMEIYTPEVIDSFKELAATGNVEF
                     LSETYAHSLSSLGDPEEFKHQVKKQEDKIKTLFGVKPKVFRNTELIYSDDISAMVSEM
                     GYKGMLTEGAKHILGWKSPNYMYSSCVAPKLSLLLKNDRFSEDLSNRFSDYSWNEYPL
                     TADKYMSWIAATPDSEQIINLFMNYEVLGSLHPASTGIFEFFKALPRFAADKGISFST
                     PSEVFTLIKPVDSISVPYPISWVDEERDCSSWLGNVLQQEAFRKINEIGERVRLSQTR
                     RIRQDWYYLQSSDHFYYMSTKHMGQGGFSPYDNPYDAFNNYMNVLSDFIVRVNAEFPE
                     NIENEELNSLLSTIKNQGEEIESLQKELDKLKKKAAKK"
     gene            complement(18174..19442)
                     /locus_tag="ACZPB4_10005"
     CDS             complement(18174..19442)
                     /locus_tag="ACZPB4_10005"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009101 - glycoprotein biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HIR1098580.1"
                     /translation="MKALMFGWEFPPHILGGLGTASFGLTRGMAMQPDMDITFCIPKP
                     WGDEDQSFLKIVGVNQVPIVWKDVDREYVQQRVSKAGMNADQYYKYRDHIYADFSYRH
                     VTDLGCLEFSGRYPDNLLEEINNYSIVAGVIARTEEYDIIHAHDWLTYPAGIHAKNVS
                     GKPLVIHVHATDYDRSRGNVNPDVYAIEKNGMDNADHIITVSNLTRQTVIEKYHQDPA
                     KVTTVHNAVEPLSPEILAIPDKKGVKDKVITFLGRITMQKGPEYFVEAAAKVLAKAPY
                     ARFVMAGSGDMMDQMIRLAAARNISDRFHFTGFMKGKQVYEVLKASDVYVMPSVSEPF
                     GISPLEAMQCGVPSIISKQSGCAEILDYAIKVDYWDIEALADAMYSIITYPAMHEFLK
                     VEGKKEVDNIKWEYAGQKVRRIYDNVIGNK"
     gene            complement(19457..21391)
                     /locus_tag="ACZPB4_10010"
     CDS             complement(19457..21391)
                     /locus_tag="ACZPB4_10010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen debranching enzyme N-terminal
                     domain-containing protein"
                     /protein_id="HIR1098581.1"
                     /translation="MSYLKFDKTVMINLEESLTREVLRTNRLGAYHCTTVVDCNTRKY
                     HGLLVMPVPAIDDDNHVLLSSFDETVIQHGAEFNLGLHKYAGDNFSPKGHKYIREYSS
                     ETVPRTLYRVGGVIFSKEKVFSMYENRIMIKYTLEDAHSATTLRFRPFLAFRSVKNLT
                     QANGNVNQSYEEVTNGIKTCMYPGYPELYMQFNKKVKFVYEPYWYNGIEYPKEQERGY
                     PYQEDLYVPGYFEVPIKKGETIIFSAGDSAVATTRLKALYENEVVARTPRTSFFNCLK
                     NSAQQFYFRPKEDDAYLLAGYPWFKVRARDLFVALPGSTLSIDDPVRFEKIMHTAMPA
                     MRAYMENGRFDAVIREIEHPDVFLWAIWAIQQYAKHEGVEKARELYGDFVKEVIDYIR
                     DQKHPDMKLMENGLLFANGKDKAITWMNSTVNGKPVVTRSGYIVEFNALWYNALCFYT
                     ELMGGVPVEGIDPIIKSMDKSFPETFVNGYNYLFDSVNGSTVDWSVRPNMIFAVALPY
                     SPLTRMQKRAVVDIVTKELLTPKGLRSLSPKSEGYRPYYVGPQYERDLAYHQGTAWPW
                     LLGAYLEAYLRVFGKSGVAFAERMLISLEEEMSLHCIGTIPELFDGNPPFTGRGAVSF
                     AMNVAAILRVVDLLKKYNAE"
     gene            21798..23897
                     /locus_tag="ACZPB4_10015"
     CDS             21798..23897
                     /locus_tag="ACZPB4_10015"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family metallopeptidase"
                     /protein_id="HIR1098582.1"
                     /translation="MRKLLYNVVILLSAIQMTHAANNPFFGKFKTPFETPPFDKIKIE
                     HYEPAFDEGIKQMEKEVQEIANNPQPATFENTVVALERSGKLLETVSSVFFNVLGAEA
                     NDEMMEISQRVSPKLSQTSNNIFLNEKLLARVKSIYDKKEQLNLSTEDAKLLEDLYES
                     FKANGATLNKDDKEKYRKLSMDLSMLTLQFDQNALKDKNRFELLITDENELSGLPESA
                     RDAAAMLAKSKDKNGWLFNLSAPSYIPFMRYSDKRDLREKMYREYMSVGNKGDEFDNK
                     DIIKKIVNIRLEIAQLMGFKNYAEYALEHTMAKNSANVYKLLNQLLEAYKPIAINEYN
                     AVEGFALGTEKENITVMPWDWSYYSEKLRDIRFKVNDEMTRPYFELSNVKKGVFGLAT
                     QLYGITFKENKKIPVYHPEVDAYEVYDADGKFLAILYTDFFPRDGKQSGAWMNNIKAQ
                     YKDKDGKDSRPQIVIVMNFTRPTDTKPSLLSFDEVNTLLHEFGHSLHGMLAQGTYSSL
                     SGTSVYRDFVELPSQIMENWLTEKEFLDQIAVHYQTGEKIPQEMIQSLVNASNFNAGY
                     LCCRQLSFGLLDMAWHTLEQPFDGDVAAFEKKAWAPTVIMPEVPEALMGTSFGHIFSG
                     GYAAGYYGYKWAEVLDADAFSVFKSKGIFNKEVAKSFRDNILSKGGTEDPAVLYKRFR
                     GQEPTIDALLIRNGIKK"
     gene            23978..24412
                     /locus_tag="ACZPB4_10020"
     CDS             23978..24412
                     /locus_tag="ACZPB4_10020"
                     /EC_number="3.5.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004132 - dCMP deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006220 - pyrimidine nucleotide metabolic
                     process [Evidence IEA];
                     GO_process: GO:0009972 - obsolete cytidine deamination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxycytidylate deaminase"
                     /protein_id="HIR1098583.1"
                     /translation="MCEKTEKQHELDKRYLRMAAIWAENSYCKRRQVGALLVKDKMII
                     SDGYNGTPAGFENVCEDENNVTKPYVLHAEANAITKVAASSNSSKGATIYVTSSPCIE
                     CAKLIIQSGIKRVVYSENYRIADGCELLKRAGIIVDYIDLNE"
     gene            24426..26159
                     /locus_tag="ACZPB4_10025"
     CDS             24426..26159
                     /locus_tag="ACZPB4_10025"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S41 family peptidase"
                     /protein_id="HIR1098584.1"
                     /translation="MDKNKRLTVWLPIIIAASIALGIFIGNHYLSISQGKKRSYSSGN
                     KINAILDIIDEQYVDTVSMSKLVESTIPKIFSELDPHSVYIPAEDASVVNEELEGSFS
                     GIGVSFNMQTDTILVISVISGGPAEKAGLLPFDRIISINDSIFSGKKKNQGEIMKTLR
                     GAKNSTVKLGVQRGNSPELLYFDVTRGDVPVNSVDVSFEAAKGIGYIKVSKFARNTYN
                     EFITAIAKLKQAGCTSFVIDLRGNTGGYMDAAINMINEFMPEGRLIVYTEGKSFPRSD
                     VYANGTGTCKDAPIVVLTDEISASASEIFSGAIQDNDRGTIIGRRTYGKGLVQTQMSL
                     SDGSEMRLTIARYYTPSGRCIQKKYEMGNTDAYDQDIYNRYMHGEFDSADSIKMDDSL
                     KYQTVGGRTVYGGGGIMPDIFIPRDTSGVTSYYSNVVNSGVLYLYALEYSDRHREKLG
                     SFKTWEELYNYLQQQPLLSDFVNFAATKGIKRRPTLINISGKLIENQLQAYIVRNFFD
                     EAGFYPIFLKDDVTLLRAIKILQEGKSVPNAELLKQSANGDLHSQAGPTKRYGLSKKR
                     IFEDYLVRAIG"
     gene            26104..>26366
                     /locus_tag="ACZPB4_10030"
     CDS             26104..>26366
                     /locus_tag="ACZPB4_10030"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030272 - 5-formyltetrahydrofolate
                     cyclo-ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HIR1098585.1"
                     /translation="MASRKKEYSRITLCELSDKIMDRLEQTELFQAASCIALYHAIPG
                     EVQTAGFIEKWYQKKKLLLPLIVGDDLRLLLYEGPESLKPGPFG"
BASE COUNT         7818 a         6614 c         5185 g         6749 t
ORIGIN      
        1 gataagcatc cgcagagtaa cgacaggatt atatatttct tcatatcttc taatctaaac
       61 atagtacatc tttttaattc caccgccgga ttaagcgtgc agctcttttt cctccgatac
      121 cggcgtcaaa tccttcccct cataatgctt ctcgatcata tagtataaag cgggaagcac
      181 ataaagcgtg attaccgtag caaataaaag cccgtaaacg attaccgtag ccaagggacg
      241 ctgcacgtcc gaaccgatcc ccgtactgac agaggcagga agcaatccca agaccgcaac
      301 cgtagccgtc atcaagatcg gacggaaacg gtgcttggtt cccgttatca ccgcatcttt
      361 caaatcccgc tccctcgtac gtaagttatt gatatgggaa atcatgatca cgccattttg
      421 gatagcgaca ccgaccaagg cgataaaacc aaccgccgag gagacattca atgtcattcc
      481 ccgcacattc aacgccaaca taccaccaaa caaagccaag ggaacgacac tcatcatcaa
      541 agccgcctgc cggaatttac cgcaagccgc aaacaacaaa agcagcatca gccccaacgc
      601 caaaggaacc acagccccca aacgggcata cgcacgatgc tggttctcga actgtccggc
      661 ccatttcaaa tgcacggaat catgatcgta tttcacctct ttatcgatca acgcatttgc
      721 cttattcaag aacgccgtca agtccacgcc acgtaaatta acccgtaccg tcaagtgccg
      781 cttattcatc tcacgggtaa tcgtactggc accagttgtc atcttaatct ccgctacttg
      841 cgaaagagga atctttgttc cggaaccggt agtcagcaat agatttccga tacgttcggg
      901 agaattgcgg ctagcgtcat cgaaacgaca aatcacgtca taacttttac ttccgacaaa
      961 tatctgggaa atagaagctc caccgatcgc taactcaatc aaatcagcca catccgacac
     1021 gttcaagcca tactgggcga tacgggcacg atccgcaata atctgcaatt gcggcaacgg
     1081 aggctcttga tctaccgcta cgtcggcagc acccggtatt tccttcaaca cattagcgac
     1141 ttgatccgca atatggcgac tttccgtaat atcatcgcta taaatcttca gcgccaaatc
     1201 actatgagcc ccagcgatct gatccatcac catatcgatg atcggctggg agaaaccgac
     1261 cgagtagccg ggcatggtct ccaacttagc cgccatttcc tcgatcagat ccgctttcgt
     1321 cttaccgaat ttccatgtac tatagggttt caatcccacg ccacactcca catgagagag
     1381 tgagaacgct tccgccccct catcatcgcg accgacttga gtcattacat atgagacttc
     1441 cttaaactct ttcaaagtct tccgaagctc cgcccccatc tccttcgatt tctcaatgga
     1501 aatacccgga ggaagctgta cctgtatcca gatcgccccc tcatccaacg gaggcaagaa
     1561 gtcttttcct acggtataac ttaaaatccc cgctcccagc aatatcgcca gtaacggtac
     1621 aataacccgt cttggcttct ccatcaatcg gacaatttgt gaatgataag ccgtggaaag
     1681 tttctccaac caacgattat ggtaaatctt tcccggctta cgatacgcat aaaaggccaa
     1741 tcccggaatc aagaacaaag ccacacacaa agcgcccagc aaagcatacc ctacggtata
     1801 agccatcggc gtaaacaatt tcttctcaat atgctcaaaa gcgaacaaag gaagataggc
     1861 tgttataata attaatgtag agaaaaagat cgggcgagcc acctcagtcg tacggcgcaa
     1921 gatcgaatct tccgtcaata cctcatccgg atgccgttcc cttttcttca agaccgtctc
     1981 catcatcacg atcgctccgt ctaccaaaat accgaagtct atagcgccta aggaaagtag
     2041 gttcgcagga atattcgtaa catgcatcaa gataaaggca atcaatagag acaagggaat
     2101 ggttaaggcc accaacaaag cgccacgcca actccccaag aataagatca gtactaagac
     2161 aaccaatacc ataccctcga acaacgtatg cgatacggta tgcaaggtcg tattaaccaa
     2221 atccgtacga tccataaacg gatggatacg ggttccctcg ggaagtgtct cgttatttag
     2281 ttcgtctacc gccttatgca catcatccaa cacccgggac ggattctccc ccctgagcat
     2341 ttgcacgatg ccttccacgc catcggaata atcacgggta tcgtccgtaa aacctaaaac
     2401 gcccttacgc tccaagtttc cgtatttcag tttaccgata tcattcaagt agaccgggac
     2461 accattcacg gtcttgatca cgatatgccc caagtcttcc aagtccttaa ccagaccgat
     2521 tccacggatc acataactca aatccccccg gcttaacata ctaccaccgg cgttcacgtt
     2581 attcttctct atcttttccg taatatcccc taaggtaatg tcgtattgct ccatcttata
     2641 agggttcacc tcgatctgat attgggtagt gataccgccg taattactta catccgctac
     2701 acccgtaacc tgtttcagtc tcggaataat tacccattta tgcaaatcgg tcaactccct
     2761 caagtctaaa cggtcacttt ccaccacata acgaaagatc tctcccgtcg gcgaagtcaa
     2821 aggatttaag ccgggaaccg cattataagg aagctccacg tctaccaacc gctcttgtac
     2881 acgttgccgg gcccaataat cctcaatacc atcatcaaaa accaatacga ccgtagataa
     2941 accaaacgta ttcttgctac gcattacgtt tagtcccggc agaccattca tagcccgctc
     3001 gatcggaata ctgatttgtt gctcgatctc ctcggcggcc aatccgggaa cctgcgtcac
     3061 gacttgcacg gtggtatcgg cgatatccgg ataagcatct atcgccaacc gcgtccaaga
     3121 ataataacca acgatcgcta agaacagaaa taacacgaac atcagtcctc gccgatgtat
     3181 cgccaagtaa ataatccttt tcataatccg ttagcgtgcg tcaagtaaat aaaacgctcc
     3241 cgtaactacg atctcgtcac ctacgttcaa gccggataaa accaccgtct tgccatcttc
     3301 agtatggccg gtctcgatct tttgtttccg gtaatcgtta ttccccaatt ccaccaatac
     3361 gtacatgttc tcctcttcct gcaagatagc ggaagtaggt atacggatca cctccgcctc
     3421 acggtcgctc agcttgaccg tgccgtacat ctccggcttc atcaaacggg tactgttatc
     3481 gcactcgatc aagacctcca ccgaacgggt atcggggtcc agcatctcgc tgatgtgata
     3541 aatctttccc gatatcggtt tatccggcat ggctaccaac cggatttcca cctcatccaa
     3601 agcctgtatt aaactcaaat ccttctcttt tacatgggcg accacccata ccttgctcaa
     3661 atcggcgatg acagctacag gctcggcgtc ctctttcata tattgcccga ttacgatctg
     3721 atctttcacg acctcaccgg ctataggcga gcgaacgatc aatggttgcc ccaaagccat
     3781 ttcatccgga ttaatctgaa agactttcaa tgcggctacc atattctcat agtctttttt
     3841 ctttaactcg taattcacct cggcctcttc caattccttt tggacaccaa ccttgttttt
     3901 catcaagtct ttctcccgat tcaagctttt caaagccagt tccatctctt ggcgagcttg
     3961 gtaataagat ttccccgcct cataaacagc gggagcgcta atctcgaaga tcggactacc
     4021 cggggccact ttctgcccta agcgaacgaa cgatttcgta attcgcccgc ttaccggtga
     4081 agccacctcc gcgtaattag aaggaatcgc ctgtacgacc cccgaggtgg taaactccat
     4141 acggtaaggt tcccgtttaa ccgtttcctt tgtcaacttg gataaaacag gagattcgga
     4201 accgatatgt ataatatccc ctttgagtgt tacggcatgc gcagactcat cctcttgctt
     4261 ttgggtatgg caagagcata gtactatcgc tggaagcaat agtaaaaata tagatttcat
     4321 ataagatgcg taaaatgttt agtataaaaa gagattctaa tgcttgactc aaattactat
     4381 accaaacgag ggaggcgcac gggattcgcc acgccgcaca agacgcaaga caacctcttt
     4441 ctttagaaag acgagcacta ccatcaaaag cgcccaagcc ataaccaaag gtaagtacgg
     4501 aattaactcc atacacaatt cggtcagctc ttcaatcgta ttaaacgcta ccgtactatg
     4561 ctcatgatga ggcaagccgt cggctcccgg cagataggga tgagagtgag tgatactata
     4621 gtttaggaaa tgatgcgtat gggtaaaggc cgtgccaccc acgtagtaac tcataaagag
     4681 tactaccaag aggggtctta accacttcaa gctacgcatt gttttcattc gccatctgtt
     4741 tactccgcaa agttataaaa gaaactgcca tttcatttgc aataagtcaa aatttattcc
     4801 tttatttgca tacactgaat aataaacagt catatcaatg aaataaacac tactttatga
     4861 gaaaaatctt acttgtttgt gcggcattag cctgcatgac agtctcccct gtaccagctc
     4921 aggacgctgc cgtaaaaaaa atcatcgaga tgggtcagaa cgataatcaa gtgatgcatc
     4981 agctggatat ccttacgaac cgctttggcg gacgtttaat aggttccgac gcttatgaga
     5041 acgccgccga gtggatggtg cgtgagttta agagttgggg actcgatgtc caattagaag
     5101 aggccggtac cgtccctgtc ggctttaatc gaggaccttg gttcggacgc ttgttgagcg
     5161 acaacggaat gatcctgcat ttcgccaccc cttcctacac ttccggaacg aaaggcgtgc
     5221 aacgtgggca tgcggtgatg gagcctcgta acgacgagga gttccagcaa atcaaaggaa
     5281 gattgaatgg tgcttgggtt cttatctcag ggaaaaatgt aggttggcct atcgaccgct
     5341 ccgcctcggg ggattccatc cgtgtggaga tcaagaaaga gaacaacgag atcatgaaga
     5401 aaaacaatga tctaagacgc cgcaactggg aaaacgggga gaaaaacgag atgttgcctt
     5461 ataaagaatt ccccggatta tattataagg aaatgtgcga ggccggagct ttaggtttta
     5521 tccaatcctc caccgtacct atccgtgcgt tatacgaccg gaaaatgatg aacgacccga
     5581 atacgaactt cgacaatctg ccggaacttc cggatatcaa attagacgag catcaatttg
     5641 cgatcatcga acaaatggtg aaagagagac gtacattcga actagagttc gatattcgta
     5701 atcattttaa attaggcccg gttaaatacc ataatgtcgt agcgtctatc aaaggcagca
     5761 aatacccgga cgaatatgtt attatcagcg gtcacctaga tgctttcgac gtggctaccg
     5821 gaggcatcga ttgcggtact ggaatcggac cgatgatgga agccgctcgc atgatcgcca
     5881 aatccggagc caagcctaag cgcacgatct tatttatcgg attcgccggt gaggaatttg
     5941 gcttattagg agcacaagct tgggtgaaag cgcataagga taaattaccc aaaatcgcta
     6001 atttgttcaa tcgtgacggt ggcccggaac ctcctgtcgg tatctccgtc cctcaagcca
     6061 tgtatgatga tttcgtgaag atcagcgaac ccatccaaaa aatccgtccg gactatcctt
     6121 tcgaggtaaa agttcgtgaa ccccgtaaac gcccgacacg catgggggga acagacgcat
     6181 cagttttcgc catcgaaggt gtccccacat taggtttcac cacagaggat ttcaaaggat
     6241 atgattttga ttacggcgaa atctggcata cggaacggga tttatacaca aagaacatcc
     6301 ccgaatacca agaacatacg gctactgtta ccgctatcat agccctcggt gtagcgaatc
     6361 tggataagca attatcaaga gaaggtttat ataccgaaga gtaggtcagc acgatcgcta
     6421 ttataaggag tttacaatgc ctattgtaag ctccttatga tgggcatcat aaaagactta
     6481 caatgcccat tataagaaat agaaaaagga tatgccctaa taggcatatc cttttctcat
     6541 tctagggtga aagatggggc tcgaacccac gaccctcgga accacaatcc gatgctctaa
     6601 ccaactgagc tactctcacc atataaaaaa acctttcatt cttcatagac gccttggttt
     6661 ataaaacctt gttttattca taacaagatt tttatctaaa aaaccacaat gggtgaaaga
     6721 tggggctcga acccacgacc ctcggaacca caatccgatg ctctaaccaa ctgagctact
     6781 ctcaccatat ccgcctttca aaggcttccc cctttaagac ggcgcaaaga taggtataaa
     6841 ttctgattac acaaaccttt tgcgaacttt tttatccatc cacttactta tagatcgctt
     6901 tctttcccgc taacaatgtg ttacgcatca aagaaatgat tgtcataggc cctacgccac
     6961 ccggaaccgg agtgatatag gaacatttag gagcgacctc attaaacaag acatctcccg
     7021 ttaacttaaa tccgctcttg gttatgctgc ttggcatacg ggttgttccc acgtcaacga
     7081 tcacggcgcc ttccttcacc atattccctt tcaagaattc aggaacacct aaagccacga
     7141 taataatatc agcagacaag cacatctcct tcaagttctt agaacggcta tggcatacgg
     7201 tcaccgtaca atcgcccgga taagatttct gcatcatcaa ggtagccatc ggcttgccga
     7261 caatattgct gcgtcccaaa accacgcaat gctttccttg cgtctcgata tgataacgct
     7321 tcaataattc caagataccg gcaggcgtag ccgatacgaa acaaggtaaa ccgatagaca
     7381 tacgtcccac gttaatcgga tggaaaccgt ccacatcttt acgataatcg atcgcctcga
     7441 tcaccttctg ctcggatata tgtttcggaa gcggaagctg tacgataaag ccatccacat
     7501 ccggatcatt atttaactca tcgaccttac gaagcaattc ttcctccgta acatcctcct
     7561 caaagcgaat taaggtagac ttaaaaccaa tctcctgaca agtcttgact ttactagcca
     7621 cataagtctc gctaccgccg tcatggccca ccaaaatagc agccaagtga gggatcttac
     7681 ctccggcagc cttgatctgg gctacctcct cagccatctc cttcttcatc tgagcggaaa
     7741 cggccttacc atccagcaat tgataatgtt gttcttccat attattgatt gtctcctgtt
     7801 aattaacgtc tgaacgaggg cttcatcgaa ggtagcttca tcttccccga cttcgcggaa
     7861 gtaagcatac gcatcatctt acgggtctca tcaaattgct tgatcagctt gtttacctcc
     7921 tggatgctcg taccgctacc tttggcgata cgctgacggc gtgagccatt caagatagcc
     7981 gggttgctgc gctcatccgg agtcatcgaa taaatgatag cctcgatact cttgaacgcg
     8041 ttatcatcga tatccacatc tttcaatgcc tttcctacac ccgggatcat ggatgccaac
     8101 tctttcaagt tacccatctt cttgatctgt tggatctggg agataaagtc gttaaaatcg
     8161 aactggttct tagcgatctt cttctgcaaa cgtttcgctt cttcctcgtc atattgctct
     8221 tgcgcacgtt ccaccaaaga cacgatatca cccatgccta agattcgatc cgccatacgt
     8281 tcagggtgga aaatatccaa ggcatccatc ttctcgcccg taccgacaaa cttaatcggc
     8341 ttatcaacaa ccgtacggat cgacaaagcg gcaccaccac gggtatcacc atccaacttc
     8401 gtaagtacga cgccgtcgaa gttcagccgc tcattaaatt ccctcgcggt attcacggca
     8461 tcctgacccg tcatggcatc taccacgaac aaggtctcat ccggctggat agcgctcttg
     8521 atagcggcga tctcgttcat catctgctca tcgatagcca aacgaccggc ggtatccacg
     8581 atcacgacgt cattgccttt agcccgtgcc tcgcggatag cgttcatagc gatctccacc
     8641 ggattcttat tctccaattc catgtatacc ggaacaccca cctgttctcc gactacacgc
     8701 aactgctcga tagctgccgg acgatacacg tcgcaagcgg ctaataatgg tttcttattt
     8761 ttcttggtct ttaataaaga cgctagttta ccagtgaaag tagtcttacc cgaaccttgc
     8821 aaaccggaca tcaatataat ggcgggattt ccctgcaaat tcacgtcgac tgccgtacct
     8881 cccatcaagc tggccaactc atcgtgaaca atcttaacca tcaactgact aggcttaacc
     8941 gatgtaagca cgttctgtcc taaagccttc tcttttaccg tatccgtaaa actcttggca
     9001 accttataat tgacgtcggc atccaacaac gctttacgca catccttcaa tgtttccgcc
     9061 acattgatct cggtaatctt gccttcgccc ttcaacagtt taaacgatct gtctaacctt
     9121 tcgcttaagt tctcaaacat aattcgtatg tgtatttata ttattttcta ctggattaag
     9181 gggcaaaggt acgaaaaaga gatgagtatg cgatgaaagc gatctcgaaa ttcttcactt
     9241 ctcaacgttt tagtatacgg atcgaattaa gaaccgccag caaagataca cctacatccg
     9301 cgaaaacagc ttcccaaagc gtggcaaaac cgaaggctcc cgccacaagg actatcacct
     9361 tcacgccaat agatcccacg atattctgac ggacgatatt ccgggtagca cgtccgatag
     9421 aaatagcttc cgctacttta gagggctggt ccgtttggat aaccacgtcc gcgctctcga
     9481 tggccgcatc cgatcccaat ccacccatcg caataccgac atcacttaaa gccagtaccg
     9541 gcgcatcgtt catcccatcg cccacaaagg caaccgactt atccgtctcc gccgttaatc
     9601 gctctatata agcggcttta tcctccggca gcagattacc atacgcttta tcgacaccca
     9661 aacgctcagc gaattgattc acgatctctt gcttatcccc ggacaacaag cgaatatctt
     9721 taacatccag atcctttaac cgacgaatcg catccacggc atccttcttc aaggtatccg
     9781 aaaggagaag atgccccgca tatttcccat cgatcgtaga aaccaccacg gtagaaacac
     9841 tatcggataa ttccttcggg acaggaatat cacgttcggc caataaacga atgttaccga
     9901 caagcacctg ccgaccgttc acgatagcct cgacaccatg ccctgccaat tcccgcatgt
     9961 cagtgatttc catcggcacg ctatcttgtt tttccgcata gcgaactaca gcctgcgcta
    10021 ccggatgggt acttttccgc tctactgata acaaaacact caaaagatca gaagccggga
    10081 tacccgtgct ttccaccatt gtgacctcaa aacgcccggt agtcaatgta ccggtcttat
    10141 cgaacgctac cgtatttacc cgtgtgatcg catctaaata attaccaccc ttaaataata
    10201 tcccggcacg agaagcggcg cctataccac cgaaatatcc gagcggaaca cttataacca
    10261 aggcacaagg acaagaaata accaagaaaa ccaatcccct atataaccaa tccgagaaaa
    10321 catactggaa agaaggcgtc accatcccta ccaaggctgg aaccgacacg attagaaacg
    10381 acagaagaat cacgattggg gtataaatcc gtgcgaaacg ccgaataaac aattccgccg
    10441 gcgctttccg ctccgaggca tctttcacca aagccaaaat acgggccaag gcactttgct
    10501 cgtacggccg attcacttgt atacgtaccg cctgcccctg cacgatcatt ccggcaagca
    10561 cttcctcacc ctcacggata gaacgaggca tactttcccc ggttaatgcc gaggtatcga
    10621 actgtgcctc ggcttccaat aaaacgccat ccaaaggcac acgtccgccg ggtttcacct
    10681 cgatccgctc gcctactttt acatccttcg gagatacatt catatatgta cccgtccgcc
    10741 atacatccgt tcgttccggc cggacatcta acaagtcact gatattcttc gaggctttat
    10801 tcacggctag aagttgcaac ctctctccta ccgtatagaa aagcatcacg gctacggcct
    10861 cgggatactc cccaatacaa aacgccccaa tcgaggcgat cgccattaac gagaactcac
    10921 taaaaaagtc tttccgcaaa gccgcttccc aagcttctcg cataacagga agtcctaccg
    10981 gcaaaaaagc gaccagaaac caaatggcct ctatccaaga ctcagcaaac caacttatcc
    11041 ccgagtactt cccgataagt cctatcacca acaaaacgaa agaaatcgtc ggcatccata
    11101 aaccggaact tccgtgcgaa tggcaatgtt cgcatccaca tgttgtactc ataatcttat
    11161 ctattttaat tatttacttc ttgattacgg tacaaaggta agagaaggga gttgcaactt
    11221 gattgcaaat tatcagggtt tctaggaacg tcgcttatta cacaatgggc aaacaccctt
    11281 taccgtataa ttaatggtat ccattatata tccttccggc aattgagcga ccgggatctt
    11341 gatattattc aaacaagagg ttttacggca tacctcgcag aaaaaatgaa tatgcctatc
    11401 acccactggg catgtctccg aacggctctg gcatatctca tattttatag agccactacc
    11461 atcttcgaaa gaatggatcg catgatgttc caataacaag gccaatgaac gggaaatggt
    11521 cgatttatcc aacgtctcca actccgcctc caattcgaac agggaagccg ggctggttcg
    11581 ttctgataat ttttgcaaga caaggatccg tgcggcagta ggccgtactc cttttcctac
    11641 caacatatct tcacattgct tcgtggacat gagttacctt tcttatttga ttacaataca
    11701 aaaatacgaa caatttccca atattcacag ttcaaaaaaa gacgtacgtg ttttttcccc
    11761 tcatatactt atattctttt attttgccaa gaggctttct ttaaatagat tacgctagcg
    11821 acgagcaatc cactatagta aatagcctct gtcaagaagc atacggctac cggcaaacgt
    11881 aaacgcatcc ccgcgacata tacaaaaagc acatacagaa tcaataccgc cgcttccata
    11941 aaaagcgcag aacgtgtatt tcccgtaccc gacaccccgt tgaacgccac attagctacc
    12001 gatccgatca ataaagaacc gacaatcacg tagacggatg gaaccgaggc cgccactaat
    12061 gaagcgtcat tcgtataaac agacacgacc catcccggca tcaaactgac aatagcggca
    12121 aacacgacca taatgcccaa agataactta cagatcttcc agatagtcgg tataacttga
    12181 ttgatcgctc ccgccccgat actattactc acgaacgtgt ttgtcgtggt cgccaaggaa
    12241 ttaacgggaa tcaacatcac gacgtaaata ctacgtacga tattcgccac cgccaactcc
    12301 cgttgcccca aatgctccac agcgataaag aacataaacc aagtagcgat agacaagaaa
    12361 tattgcagca tcgtgaacac ggaaatatcc agcacccgtt tcaacaagcc aaaatcgaaa
    12421 gaacgaatct ggttaagcgc atatttacgt atatctacgg taagtctcgt gtaaaccacg
    12481 aaaaagagaa tcgataccgc ctcggctatg acggaagcga tagccgcccc ttgaataccc
    12541 atctttggga atccggcatg tccgaaaatc aaaagataat ccagtaagac attcgtcatt
    12601 gccatcaaga cagcgttcaa tgtcaacacc tttgtacggg taataccaat aaaaagagcc
    12661 cggaacatca cgttcacgaa agagaagaag aagccaaaca cacgccaatt caaaaattcc
    12721 tccgtggcat tcaagatagc gtccgaagaa atcaatacac gcatcacgtc tcccgcgaaa
    12781 aaacgagaaa acaagaacaa tatagcagcc agcgacaata ggaagaaaac gccttgtatc
    12841 atgacaggcc ctatctggtc ataacgtccc tctccgtttc tacggccaat cacgatttga
    12901 gatcccgtac taaaaccgaa ggcgatcgta aaagcgcaga tataataaag tcctcccata
    12961 gcggaagccc ccaactcgac ttcaccaacc ctacctagaa aagccgtatc agtcacgttt
    13021 atcacgtttt gcgccaacaa gctcaaaaag atcgggtagc taacattcca tatattcctg
    13081 ttcgtgtaca taactcgctt attacttaaa tttatgaaga taaaaaaagc ccgccgcatc
    13141 ccgacgagct tttcttatga ttagagatct ctacaaagcc tagcgtctgc tatatcaact
    13201 tatttgtcgc cgtatcggga aataccacgg aaggcttgaa tgttttcgcc tcctcgaaat
    13261 ccatcatggc atacgacata acgataataa tatctccggg ttgagcctta cgggcagccg
    13321 ctccgttcaa gcaaaccact cccgagccac gttcgccctt gataatatac gtctcaaaac
    13381 gttctccgtt attattattc acgatcgaga ccttctcgtt cgcgatcaaa ttagcggcgt
    13441 ccaacaaatc ctcgtcgata gtgatgctac cgatatagtt taagttagct tccgttaccg
    13501 ttacccggtg aatttttgac tttactacct ctataaacat gtatgactta taattagtat
    13561 ttgatattgt cgatcaaacg tacctctccg caatataccg tgatgcaacc taccggataa
    13621 tcggtatccg accagttctt gatagactct aacgtattgc catctacgat ctcgtagtac
    13681 tcaacttcca tgactggatc gctattaatc gtattgacaa catagtcaat cacttcttgt
    13741 acgctttttc cgggcacaaa ggtagtactt tcttttaacg tacgagcaat taacggagct
    13801 ttttgacgtt gttccggtgt caaacgggta ttccggctac tcaaggccaa gccatcgccc
    13861 tcacgaacga tcggacaagc attgatcgtt acagggatat tcaattgttt caccatcgcc
    13921 cggatcacag cgatctgctg gaaatccttt tccccgaaat aagcgttatc cggctctacg
    13981 atatagaaca acttacttac tacctgcgct acaccgttaa aatgccccgg acgcttagcg
    14041 ccttccatta cctcagatac cgttcccaaa tcaaatgtac gggtatctgg ctccggatac
    14101 atctcttcta cagagggagc gaatacatag tcacagccgg cagattctaa taacacacaa
    14161 tcagcctcca acgtacgggg atacgtttcc aagtcgtgtt tgtcattaaa ttgggttgga
    14221 tttacaaaaa cactgactac acatacatca ttgtttttca cgcaatgttg tactaagcta
    14281 agatgtccat tatgcagtgc tcccatggta ggaacaaagc caattttctt attatcctgc
    14341 tttgcctcag caagataagc cttcaaatct ttaatactat ttactatttt catcagatag
    14401 atgcttaatt gacggtgcaa agcaactaaa taattaccgt aaataaaaga tttttcgtat
    14461 ctttgtagcg tctttataaa actagtttac agaatggatg caaaaaaaat cttgtttata
    14521 gcccaagaaa tcactcccta ccttcccgaa tccgagattg cgacaatatg tagaaatttg
    14581 ccgcaaggaa ttcaggagcg tggtcgcgaa atcaggacat tcatgccaaa attcggaaat
    14641 atcaacgagc gccgcaatca gttgcacgag gttatccgtc tgtctggtat gaatcttatt
    14701 attgacgaca cggaccatcc tctgatcatt aaggtagcat ccattcaatc ggcccggatg
    14761 caggtttact ttattgacaa cgaggatttc ttccaacgga aatccacggt cagcgatgag
    14821 aatggaaatg agtatgaaga taatgacgat cgttcgatct tctatgtacg cggagtattg
    14881 gaaaccgtaa aaaaattgcg ttggattcct gatgtaatcc attgccatgg ctggatgtca
    14941 gcgttaacgg ctctttacat caagagaatg tatgccgatg acccgtgcct gcgtaatgcg
    15001 aaaatcgttt attcgatcta caacgatgac ttcaagaacc cgctaaacaa agatttcgcg
    15061 acaaaactga aggcggacgg agccaaagaa gctgacttga agttaatcaa ggcagataca
    15121 agttttgtgg gcctaaccaa attagcgatt gatttcgctg atggtgtaat ccaaggtagc
    15181 gagacgatca atcaagaagt ccttgattat atctctgcca agaaagatac tcctttcctt
    15241 ccctatcagt caccggaaac ttatatggac gagttcaata agttctacga cgtggtattg
    15301 gattctaaca cgaaataata aatgtagtaa tgaaaatcaa gcttttaata cttggacttg
    15361 gccttggtgc tagcattttg gccgggtgta atgatgattt tagttcgata ggaacaagta
    15421 ttcagccagg cgacgataca attgcggtat atatggacac gttccagata caagccacta
    15481 cggtgcaatt agattctatt tacgcaaggt ctactagcgc ccagttgggt gaactctacg
    15541 atccgctgta tggtaacctt gtatcggatt atatgtgcca attctattgt ccgagtgatt
    15601 ttcaatttaa gcatacacct tatgagggaa aaattgattc ggtggaattc aatatatatt
    15661 ataatggttc caataaaaac ggtgtatggg taggagactc cttggcgcct atgcgtgcgg
    15721 agatctttaa aattacaagt ccgttacaaa agaattttta tacaaatatt gaccctaagc
    15781 aatattgcaa tatgcaagag tcaatgggtg ctcaagctta tacagcttat aacacaagta
    15841 tatccgactc ccttagaaac tctgatggtt acagccctca tgtaagcatt aaaatgccta
    15901 ctgagttcgg acaaaaattt tatgatgaaa cgattaataa tccgggtaca ttcaagaatc
    15961 aagaaacttt caatgagttt ttcccggggc tttatgtaac aactaccttc ggtagtggta
    16021 atatattgtc cgtggctagc tctgtcctta agatatatta taattatgcg gttaaaagca
    16081 cagcaggaaa agactcttta ataaccacgt gggaagcttt ctccgtcact aaagaggtca
    16141 ttcagctaag tcgtttcaaa aatacggata tgagtcaatt gctacaaccg aacgacagct
    16201 atgcattttt taagactcct gccggcgttt gtacacgcat cgttcttccg acacaggaaa
    16261 ttactccgat catggaaaaa cgtatcgtga ataatttacc actagagtta aaagcgatgc
    16321 cgcaagaaga ttggcaatat gcgctggctc ctcctcctta tttattgatc ttgccggagg
    16381 attctgtaaa gagtttcttt gagggtagtc aaattgacaa taatgtaacc tcgtttctat
    16441 ccaaggctta cgatgcgact actcgtacgt actcattccc gaatcttgcc aatttattaa
    16501 aatatcagat ggagaataat ccggacaaag atttgagttt acttcttatc cctgttcaac
    16561 ggacaacgac cacaggtaac agttacggtc aaagtacagt tgttacaaca gccatcacga
    16621 attatctagc tccctcaggt gtaaagatac gaaaggatga agaggtgatg aaaattggta
    16681 ttacatcatg taaatatgtc agatagcaaa gaatctatat aataaaaaaa gcgagatgaa
    16741 aaacatctcg ctttttttat atccgtatct ctaaggcaaa aaataacggg tccctaaaag
    16801 gacccgtcac tctccaaaaa tagtctagtc aaatcaatta acgacttatt tcttcgccgc
    16861 cttctttttt aatttatcta attctttctg tagactctcg atttcctctc cttgattctt
    16921 aatcgtagaa agcaatgaat tcaattcctc attctctata ttctccggga attccgcatt
    16981 tacacgaaca atgaaatcgg aaagaacatt catatagtta ttaaatgcat catacggatt
    17041 atcgtaaggg ctaaagccac cttgtcccat atgctttgta ctcatataat agaaatggtc
    17101 actgctctgc agatagtacc agtcctgacg gatacgacga gtctgagaca aacgaacacg
    17161 ctcaccgatc tcgttaatct tacggaacgc ttcctgctgc aatacatttc ctaaccaaga
    17221 actacaatct ctctcctcat ctacccaaga gatcggataa ggaacggaga tagagtctac
    17281 cggcttgatc aatgtaaata cttccgatgg agtagagaag ctaatcccct tatccgcagc
    17341 aaaacgaggc aaagccttga agaactcaaa aataccggtt gaagctggat gcaaagatcc
    17401 cagcacctca taattcataa acaaattaat gatttgctct gaatccggag tagcagcgat
    17461 ccatgacata tacttatcgg ctgtcaaagg atactcattc caactataat cactgaaacg
    17521 gttcgataaa tcctcgctga aacggtcatt cttcaataat aaactcaact tcggagctac
    17581 gcaagaagaa tacatatagt tcggactctt ccaacctaag atatgcttag caccctccgt
    17641 caacatcccc ttatagccca tctcagaaac catagcggaa atatcatccg agtaaatcaa
    17701 ctccgtatta cggaacactt tcggtttaac cccgaataaa gtcttgatct tatcttcttg
    17761 tttctttact tgatgcttga actcctccgg atctcccaag gaagaaagag aatgagcata
    17821 agtctcagac aagaattcca cattccccgt agccgccaat tccttaaagc tatcgatcac
    17881 ttccggagta taaatctcca tctgctccaa cgctacgccg gaaatagaga acgctacctt
    17941 aaacttacca ccactggtct taatcatctc caaaatagtc cggttagccg gcaagtaaca
    18001 ttgttcagct atacgatgga taatctcctc attctggaaa tcatcgtaat agtaatggtc
    18061 gttacctata tcgaagaagc gatatctttt taaacggaac ggctgatgta tttgaaaata
    18121 aaagcagatc gttttcataa tattgtttgt tttatttttg tcttgtcgtt aatttatttg
    18181 ttacctatca cattgtcgta aatacgacga accttttgtc cggcatattc ccatttgata
    18241 ttatccacct ctttcttacc ttccactttc aagaactcat gcatggcagg ataagtaata
    18301 atagaataca tggcatccgc taacgcctca atatcccaat aatccacctt aatcgcataa
    18361 tccaagatct cggcgcaacc ggattgttta gaaatgatag agggtacacc acattgcatg
    18421 gcttccaacg gagagatacc aaaaggctca gaaaccgaag gcatcacata tacgtcactg
    18481 gctttcaaca cctcatagac ctgcttgccc ttcataaatc cggtaaagtg gaaacgatct
    18541 gaaatattac gtgctgcggc caaacgaatc atttgatcca tcatatcacc actaccagcc
    18601 atcacgaaac gtgcataagg agccttagcc aaaacctttg cggcagcctc aacgaaatat
    18661 tccggccctt tctgcatcgt gatacgacct aagaatgtaa taaccttatc ctttacaccc
    18721 tttttatctg ggatcgctaa aatctcagga cttaaaggct ctacggcgtt atgtacggtc
    18781 gttaccttag cgggatcttg atgatatttc tcgatcaccg tctgacgagt caaattactc
    18841 accgttatga tatgatctgc attgtccata ccattcttct caatcgcata gacatccgga
    18901 ttcacattac cacggctacg atcataatcc gtagcatgaa catggattac caaaggctta
    18961 ccactcacat ttttagcgtg aatacccgcc ggataagtca accagtcgtg cgcatggatg
    19021 atatcatact cttccgtacg agcgattact cccgcaacga tcgaatagtt attgatctct
    19081 tccagaagat tatccggata acgtccggaa aactcaaggc accctaaatc agtcacatga
    19141 cgataactga aatccgcata aatatgatcc ctgtacttat aatactggtc agcgttcatt
    19201 cccgctttgg aaacccgttg ctgcacatat tcacggtcaa catccttcca aacaatcgga
    19261 acttggttga cacccactat ctttagaaag ctctggtctt catcgcccca gggcttcggt
    19321 atacaaaaag taatatccat atcgggctgc attgccatgc ctcgtgtcaa accgaaactg
    19381 gccgttccta aaccgcccaa gatatgagga ggaaattccc atccaaacat taatgctttc
    19441 ataatggtac ttagttttat tcggcgttat acttcttcaa caaatccaca acacggagga
    19501 tagccgcaac attcatcgca aaagagacag ctccacgtcc ggtaaacggt gggttaccat
    19561 caaacaattc cgggatcgtc ccgatacagt gtaatgacat ctcctcctcc aagcttatca
    19621 acatacgttc agcaaaagca acgccactct ttccgaatac acgcaaataa gcttccaaat
    19681 aggcgcctaa caaccacggc caagcagtac cttggtgata agccaaatct cgttcatatt
    19741 gcggccccac ataatacggg cgatatcctt cgctcttcgg actcaaggaa cgcaagccct
    19801 tcggggtaag caactctttc gtcacgatat ccactacggc acgtttctgc atcctcgtca
    19861 atggggaata aggcaatgcc acagcgaaaa tcatattagg ccgtacgctc caatctaccg
    19921 tagaaccatt cacggaatcg aacaaataat tatacccgtt cacaaaggtt tccgggaacg
    19981 atttatccat cgacttgata atcggatcaa taccctcgac aggtactccc cccatcaatt
    20041 ctgtatagaa acaaagagca ttataccaaa gagcgttaaa ttccactata taaccggaac
    20101 gagttacaac aggttttccg tttacggtag aattcatcca agtaatcgcc ttatcttttc
    20161 cattagcgaa aagtaaacca ttctccatca atttcatatc gggatgtttc tggtcccgta
    20221 tataatcgat aacttctttc acgaaatcgc catatagctc acgtgccttt tcaacgcctt
    20281 catgcttagc atactgttgg atcgcccaga tcgcccataa aaagacatcc ggatgctcga
    20341 tctcacgaat caccgcatcg aaacgcccat tctccatata cgcccgcatc gccggcatcg
    20401 ccgtatgcat gatcttctca aaacgaaccg gatcatcgat agacaacgta ctacccggaa
    20461 gggctacgaa caaatctctc gcacgtactt taaaccatgg atagcccgct aatagataag
    20521 cgtcgtcttc cttgggacga aaataaaatt gctgagcgga attcttcaag caattgaaga
    20581 agctagtacg aggcgtacga gctacgacct cattctcata cagtgccttc aagcgggtag
    20641 ttgccactgc actatcgcca gcgctaaaaa taatagtctc cccttttttg atagggacct
    20701 cgaaatatcc gggaacatac aaatcctcct gataaggata tcccctctct tgttctttcg
    20761 gatactcgat gccattgtac caatacggct catacacaaa tttaactttc ttgttaaatt
    20821 gcatatacag ttccggataa ccgggataca tacatgtctt gattccgttt gtgacttcct
    20881 cgtaagattg gttcacgtta ccattggctt gcgttaagtt cttcacacta cggaaagcga
    20941 ggaaaggacg gaaacgtaag gtcgtagcgg aatgagcatc ttccaacgtg tacttgatca
    21001 tgatacgatt ctcgtacatg gaaaacactt tctctttcga gaagatcaca cctcctacac
    21061 ggtaaagcgt acgaggtact gtctctgagc tatactcgcg gatgtactta tgtcccttgg
    21121 gactgaaatt atcacctgca tatttatgca acccaagatt aaattcggca ccatgttgaa
    21181 ttaccgtctc atcaaaagaa gacagtaaca catggttgtc atcatcaatc gcaggcacag
    21241 gcataacgag tagtccgtgg tatttcctgg tattacaatc aacaacagta gtgcagtgat
    21301 aggctcccaa acggttggtt cgaagcacct cacgagtcag cgactcttcc aggtttatca
    21361 ttactgtttt gtcaaattta agataactca tatgtgtatt tgggttttaa gttactttct
    21421 ttaatatcaa aatgaaatta ttttcgtttc tgagaatcaa aagtattatt taataactaa
    21481 aaaaacaaac tgtcttttat atttatttag aaaaaaaggc atccttcttc tacgataaac
    21541 ttatagatca agactttaaa aagaaaggtg ctctaaagga gtgttttcaa acatataaat
    21601 ttttgttaaa tcaatcctat tatcatattc atcaaagctc aaaatcaagg tacagccccc
    21661 cgaaaacaag cctcggttta gtcataggaa atgttctatt tttcatttta aatcaatctg
    21721 aatataaaaa cagatgccta taatgttcct gtgattaaaa tgcctacctt tgcggaaatt
    21781 ttcaaacaat ttttaatatg aggaagttat tatataatgt agtaatttta ttaagcgcaa
    21841 ttcaaatgac acacgcagca aataaccctt tcttcgggaa gtttaaaaca ccgttcgaga
    21901 cccctccttt cgataagatc aagatcgagc attatgagcc cgctttcgac gaaggaatca
    21961 agcaaatgga aaaagaggtg caagagatcg ccaataaccc gcaaccggct acttttgaga
    22021 atacggtagt agctctggaa cgtagcggca aattattaga aacagtctct tctgtttttt
    22081 ttaatgtatt aggggcagag gctaacgacg aaatgatgga aatctcgcaa cgtgtctccc
    22141 cgaagttatc ccagacatcc aataacatct tcttaaatga gaagctactt gctcgggtca
    22201 aatcaatcta tgataaaaaa gaacaattga acctttctac cgaggatgct aaattgctgg
    22261 aagaccttta cgagtcgttt aaagcgaatg gggctacgtt aaataaagat gacaaggaaa
    22321 aataccgcaa gctaagtatg gacctaagca tgttaacctt gcagttcgat caaaacgcct
    22381 tgaaagataa aaaccggttc gaattactaa taacggacga gaacgaacta tccggcttac
    22441 ccgaaagtgc tcgtgacgca gcggccatgt tagccaaaag taaagataaa aacggatggt
    22501 tattcaatct ctcggctccg agttacattc catttatgcg ttattccgac aagcgtgatt
    22561 tgcgagaaaa aatgtatcgt gaatacatga gcgtaggaaa taaaggggat gagttcgaca
    22621 ataaggacat tatcaaaaag atcgttaata tccgcctaga gatcgcccag ttgatgggat
    22681 tcaagaatta cgccgaatat gcgctggaac acacgatggc taaaaactca gcgaacgtat
    22741 acaaattatt gaatcagtta ctcgaagctt ataaaccgat agcgatcaat gaatacaatg
    22801 cagtagaagg attcgcatta ggtacagaga aagagaatat caccgttatg ccttgggact
    22861 ggagttatta ttccgagaag ttacgggata tccgcttcaa ggtaaacgac gagatgactc
    22921 gcccttattt cgagttaagc aacgtaaaga aaggcgtatt cggattagct acccagctct
    22981 acggtatcac ctttaaggaa aacaagaaaa tcccggttta tcatccggaa gtagacgctt
    23041 acgaggtata cgatgctgat ggcaagtttc tagcgatcct ttacacggac ttcttccctc
    23101 gtgacggaaa acaatccggc gcttggatga acaatatcaa ggctcaatac aaagataaag
    23161 acggaaaaga tagccgtcct cagatcgtta tcgtgatgaa ctttacccgt ccgacagaca
    23221 cgaagccctc tttgttaagt ttcgacgagg tgaacacact cttgcatgag ttcgggcact
    23281 ccttgcacgg catgctagcg caaggaacat attccagcct ttcgggaacc agcgtttatc
    23341 gtgatttcgt agaattacct tcccagatca tggagaactg gttgactgaa aaagagttct
    23401 tagatcagat cgccgttcat taccagaccg gagagaaaat cccgcaagag atgatacaaa
    23461 gcttggtaaa cgcctctaac ttcaacgccg gctacctttg ctgccgccaa ttaagctttg
    23521 gcttgctgga tatggcatgg catacgttgg agcaaccttt cgacggtgac gtagcggcat
    23581 tcgagaaaaa agcttgggct ccgaccgtaa tcatgccgga agtaccggaa gccttgatgg
    23641 gcacaagctt cggacatatc ttctccggag gatatgcggc aggctattac ggatataaat
    23701 gggccgaggt attagatgcc gatgctttct ccgttttcaa atcgaaagga atcttcaaca
    23761 aagaggtcgc taaatctttc cgtgacaata tcttatccaa aggtggtaca gaagatcccg
    23821 ccgtgttata caagcgtttc cgtggacaag agcctacgat agacgcctta ttaatccgta
    23881 atggtattaa gaagtaataa tttaccgggc ttatcgcccg gtaaatctaa ataatcacta
    23941 cctttgtgtc tggattaaaa gacaaaagag taaacaaatg tgcgagaaaa cagaaaaaca
    24001 gcacgaatta gataaacgtt acctgcgaat ggccgctatc tgggccgaga attcgtactg
    24061 taaacgacgc caagtgggcg cattattagt aaaagataaa atgatcatat ccgacggata
    24121 caatggaaca cccgccggtt ttgaaaatgt ttgcgaagac gagaataatg tcaccaagcc
    24181 ttatgttcta catgcggagg ctaacgccat cacaaaagtg gcagcctcat cgaacagcag
    24241 taaaggagcg accatttatg ttacctcctc cccttgcatt gaatgcgcga aattaatcat
    24301 acaatccggg atcaagcgag tggtctattc cgagaattat cgaatagcag acggctgtga
    24361 attattgaag cgtgccggta tcatagtaga ttatatagat ttgaacgaat aaataaaacg
    24421 tttttatgga taaaaacaaa agactgaccg tatggctccc gattatcatc gcggctagta
    24481 tcgctttagg tatctttatt gggaaccatt atttatctat cagtcaagga aaaaaacggt
    24541 cctactccag cggtaacaag ataaatgcca tcttggacat tatcgacgag caatatgttg
    24601 acacggttag catgtctaag ctggtagaga gtacgatccc gaaaatattc agtgaattag
    24661 accctcactc cgtatatatc cccgccgaag acgcttccgt ggtgaatgag gagctggaag
    24721 gttctttcag tggtattggc gtatcattta atatgcaaac cgatacgatc ctagtgatca
    24781 gcgtaattag cggtggtccc gcagagaaag caggtttact gcccttcgac cggatcatct
    24841 cgatcaatga ttctattttc tccggtaaga aaaagaacca aggagagatc atgaagacac
    24901 tccggggcgc aaagaacagt acggtgaaac taggcgtaca gcgaggaaat tctcctgagt
    24961 tgctctattt tgacgtaacc cgtggagatg tccctgttaa ttcggtcgat gtttctttcg
    25021 aagcggctaa aggtataggt tacatcaagg ttagcaaatt cgcccggaat acttataatg
    25081 agttcatcac ggcgatcgcc aagctgaaac aagcgggctg tacctctttc gtgatcgact
    25141 tacggggtaa taccggcgga tatatggatg ccgctatcaa tatgattaac gagtttatgc
    25201 cggaaggacg cttgatcgtc tacacggaag gtaagtcgtt ccctcgttcc gacgtatatg
    25261 cgaacggaac cggaacttgt aaagacgccc cgatcgtagt attgaccgat gagatctcgg
    25321 cttccgccag tgagatattc tccggagcga tccaagataa cgaccgtggt acgattatcg
    25381 gacgaagaac gtatggcaag ggtctggtac aaactcaaat gtcattgagc gacggttcag
    25441 agatgcgatt gaccatcgcc cgttattaca cgccgtccgg tcgctgcatc cagaagaaat
    25501 atgagatggg taatacggac gcttacgacc aagatatcta taaccgatat atgcacggcg
    25561 agttcgactc ggccgatagc atcaagatgg atgattcctt gaaataccag accgtaggcg
    25621 gacgtaccgt atacggcggg ggcggtatca tgccagatat ctttatccct cgtgacacga
    25681 gcggcgttac ctcttactac tcaaatgtgg taaatagcgg cgtgctttac ctgtatgcgc
    25741 tcgagtactc agaccgccat cgggagaaac taggctcatt caagacttgg gaggaattat
    25801 ataattactt gcagcaacaa ccgctccttt ccgacttcgt gaacttcgcc gctaccaagg
    25861 gcatcaagag acgtcctaca ttaattaata tatccggcaa gttaatcgag aaccaattgc
    25921 aagcgtatat cgtaaggaat ttcttcgacg aggcgggctt ctaccccatt ttcctaaaag
    25981 atgacgttac cttattacgt gcgatcaaga tcttgcaaga gggaaaatct gtgccgaatg
    26041 cggaactatt aaaacaatca gcgaatggag acttacacag ccaagcaggc cctacgaaaa
    26101 gatatggcct ctcgaaaaaa agaatattcg aggattacct tgtgcgagct atcggataag
    26161 atcatggacc gcttggaaca gacggaactg ttccaagcgg cttcttgcat cgccctttat
    26221 cacgccatac cgggagaagt acagaccgcc ggctttatcg agaaatggta ccagaagaaa
    26281 aagcttctgt tgcccttgat cgtcggtgat gatttgagat tgcttcttta cgaaggaccg
    26341 gaatccctaa aacccggacc tttcgg
//
LOCUS       DBMDTB010000055        26213 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_664_length_26213_cov_11.112707, whole genome shotgun sequence.
ACCESSION   DBMDTB010000055 DBMDTB010000000
VERSION     DBMDTB010000055.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 26213)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 26213)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26213
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_664_length_26213_cov_11.112707"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(62..355)
                     /locus_tag="ACZPB4_10035"
     CDS             complement(62..355)
                     /locus_tag="ACZPB4_10035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DciA family protein"
                     /protein_id="HIR1098586.1"
                     /translation="MQRRNTQTLGEVLRDFFEDNTELYEKMMEIRVQRAWGEVLGPTI
                     MQYTRNIYVRDKVLHVSLTSSVLRSELTLCRERLVKSLNDYAGASVITNIVFH"
     gene            complement(358..1455)
                     /gene="recF"
                     /locus_tag="ACZPB4_10040"
     CDS             complement(358..1455)
                     /gene="recF"
                     /locus_tag="ACZPB4_10040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861599.1"
                     /note="All proteins in this family for which functions are
                     known are DNA-binding proteins that assist the
                     filamentation of RecA onto DNA for the initiation of
                     recombination or recombinational repair; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HIR1098587.1"
                     /translation="MILKKLSVLNYKNILQSEVIFSPKMNCFFGNNGMGKTNLLDAIH
                     YLSFCKSHVNTPDSQIINSDQDLCVVQGNYDYEGREEEIFCAMRRRQRKQFKRNKKEY
                     DKLSEHIGLLPLVMVSPADADLIRGGSDERRRFLDLIISQQDKPYLHALIQYNKALLQ
                     RNTLLKDQSMDASLYEVLEMQLGMYGQIVYEKRKKLVEDFTPIFNEYYQTICGSAEEV
                     GLHYISQLEETELAGKLAMSRERDRILGYTSSGIHKDELEMTLGGYLIRRVGSQGQNK
                     TYLIALKLAQFAFLNKRGQTTPILLLDDIFDKLDASRVEQIIKLVSENGFGQIFITDT
                     NRKYLDEILLAMNHDYALFRVERGEVQPMEE"
     gene            1604..2287
                     /locus_tag="ACZPB4_10045"
     CDS             1604..2287
                     /locus_tag="ACZPB4_10045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HIR1098588.1"
                     /translation="MATKEKDTNKELEVEEIVSKSEQFIENNSKKIIYGIIAVALVVG
                     AVLGIKHGYLVPQEKKAAAAMFKGEQYFARDSFALALNGNGADYEGFEAIIDQYGSTD
                     AGNLAKAYAGICYYKMGDTQKALDLLKSFSGKDQMVSPAVTGLIGDCYVNMGNTKEGI
                     SYFEKAAKEADNEVISPIYLKKAGIAYENLKEYDKAVKAYTTIKDKYYTSMEASDIDK
                     YITRASAGK"
     gene            2364..2846
                     /gene="ribH"
                     /locus_tag="ACZPB4_10050"
     CDS             2364..2846
                     /gene="ribH"
                     /locus_tag="ACZPB4_10050"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009349 - riboflavin synthase complex
                     [Evidence IEA];
                     GO_function: GO:0000906 - 6,7-dimethyl-8-ribityllumazine
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HIR1098589.1"
                     /translation="MATAYQNLSEYDFNSVPDASEMNIGIVVAEWNKNITEKLLEGAC
                     NTLEKHGVKPENIVVKRVPGSFELTFGAKRLAETKELDAVIVLGCVVRGDTPHFDYVC
                     SGVTQGITELNLMYDIPFIFGLLTTDTMQQSEDRAGGRYGNKGDEAAVTAIKMVNFSA
                     "
     gene            2901..2983
                     /locus_tag="ACZPB4_10055"
     tRNA            2901..2983
                     /locus_tag="ACZPB4_10055"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2935..2937,aa:Tyr,seq:gta)
     gene            3009..3081
                     /locus_tag="ACZPB4_10060"
     tRNA            3009..3081
                     /locus_tag="ACZPB4_10060"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3042..3044,aa:Gly,seq:tcc)
     gene            3196..3528
                     /locus_tag="ACZPB4_10065"
     CDS             3196..3528
                     /locus_tag="ACZPB4_10065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098590.1"
                     /translation="MKIVKGIYVLLTMFLLMGCATVMNPYKMDNRMHKIELGMTKQKV
                     ISILGKDFESAGARITPDGPIESISYKTVTMTIADYSEGYYILSFKNGILVEWFKEKT
                     PINNNTAN"
     gene            complement(3538..3738)
                     /locus_tag="ACZPB4_10070"
     CDS             complement(3538..3738)
                     /locus_tag="ACZPB4_10070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098591.1"
                     /translation="MKTKRKKQDPLVEYIKANRKGSREAELENHGRPVSHNRIHVSKK
                     VYNRKRMKADAQRHLPYLFLVA"
     gene            complement(3790..4110)
                     /locus_tag="ACZPB4_10075"
     CDS             complement(3790..4110)
                     /locus_tag="ACZPB4_10075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4491 family protein"
                     /protein_id="HIR1098592.1"
                     /translation="MDMINFDGLLIGIVTFLIIGLFHPVVVKAEYYWGTKCWWIFLVL
                     GILGVIASLFIDSVFVSAICGVFAFSSFWTIKEIFEQEERVQKGWFPRNPKRKYPWDD
                     SEVK"
     gene            complement(4404..4787)
                     /gene="secG"
                     /locus_tag="ACZPB4_10080"
     CDS             complement(4404..4787)
                     /gene="secG"
                     /locus_tag="ACZPB4_10080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015136 - sialic acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015739 - sialic acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HIR1098593.1"
                     /translation="MYVFISILILIASILLILIVLIQNSKGGGLASGFSSSNQIMGVR
                     KTTDFLEKATWSLAGTVIVLSILITAFIPRAEHAAQSEIKQQVNDAISIDPNTIAPDF
                     GTAQQPAVPAEETPATTTPAEESNR"
     gene            complement(4795..5562)
                     /locus_tag="ACZPB4_10085"
     CDS             complement(4795..5562)
                     /locus_tag="ACZPB4_10085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098594.1"
                     /translation="MRAEDLYRLMEEPSELTEGTLLELRRIVEDYPYFQVARMLYLKN
                     LAVLNDMSFTSELERMAIFLPDRKKLFQLIEGDKYGLNSRVEHEPDMRKEDTFSLIDA
                     FLSNRNEEPEPKKEAPFLFQPSVSSDYMFWSLSKEEEEKPSGEDAENRLRHHDLIDSF
                     IKNDQQRMPGSGLEIREENSRAETPESVKDLDDEQSKSLEDSCLTETLARIYIKQKRY
                     DKALQIIKNLSLKYPEKNVYFADQIRFLEKLIINTKK"
     gene            complement(5564..6100)
                     /locus_tag="ACZPB4_10090"
     CDS             complement(5564..6100)
                     /locus_tag="ACZPB4_10090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LptE family protein"
                     /protein_id="HIR1098595.1"
                     /translation="MLKKIVNIRLSAANWLILSFLTVLATACSISYKFNGASIDYTKV
                     KTITIRDFTNQAPYVNPTLAPQFTEDLKDIYIRQTRLQLVPSNGDLELEGEITGYDFA
                     PMAVKEDAIASQTRLTITVRVRYSNRVNPDEDFEQSFSAYREFDSNLMPQQVEGTLCE
                     EIIEEIVDQIYNATVANW"
     gene            complement(6104..7294)
                     /locus_tag="ACZPB4_10095"
     CDS             complement(6104..7294)
                     /locus_tag="ACZPB4_10095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 interaction domain-containing protein"
                     /protein_id="HIR1098596.1"
                     /translation="MKVDVQQIKQRFGIIGNNPGLNRAIDVALQVAPTDLSVLITGES
                     GVGKETFPQIIHQNSQRKHGQYIAVNCGAIPEGTIDSELFGHEKGSFTGALADRKGYF
                     EVADGGTIFLDEVGELPTPTQARLLRVLETGEFIKVGSSKVQKTNVRIVAATNVNLVQ
                     AVSEGKFREDLYYRLNTVPIQVPPLRERPEDIVLLFRKFASDCAEKYRMPPIRLDDEA
                     RQLLVSYRWPGNVRELKNITERISVIEETRDITADVLRLYLPNVNVEKYPVLVKQDPD
                     QKIFNSEREILYQVLFDMKKDVNELKKLVHDIMGGNIPMPTVADDTPYAHPIHPAAVH
                     AMHPTIQDAEDVEEETLSLEEVEKEMIRKALEKHNGRRKNAAADLKISERTLYRKIKE
                     YNLE"
     gene            complement(7399..8226)
                     /locus_tag="ACZPB4_10100"
     CDS             complement(7399..8226)
                     /locus_tag="ACZPB4_10100"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HIR1098597.1"
                     /translation="MKKSVVDIYDLQEMAPFFKGRVGTWLGKLLIKCLRVDLVNKVHA
                     RNCHLRGAEFTSALLHDPIIDLSYEVHNKEILDHLPEGAFVTVSNHPIGSLDGIMLID
                     IFASRRPDFKVMVNGILTKIGAMEDNFISVVPDSHKRGANPANVNGVRLSLQRLKEGH
                     PMGFFPAGAISFYNKKEKQVRDLSWAHSVIRLVRKAKAPVYPVYFDFQNTHFFYWLGN
                     ISWQIRTLRIPTEAFNKRGKKADVYIGEPISPEEIAAIPEDKDLAEFLYKRTYGAKK"
     gene            complement(8230..9117)
                     /locus_tag="ACZPB4_10105"
     CDS             complement(8230..9117)
                     /locus_tag="ACZPB4_10105"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HIR1098598.1"
                     /translation="MSELDKEYEASLKSIETENKIDRIFYRPIGFRIARMLRGTGITP
                     NMITVISIFVGAAVGFMFYHDNLTYNICGILLLVFANILDCVDGQLARLTGIKSAIGR
                     ILDGFAGDIWFASIYIGFALRLSHDYGTDWFFALAVLSGLSHLVQANITDYYKTLHLY
                     FISKDKGSEFQSLEQVEAKHKEMKYGINKFFYFLYRWYTMLQVKATPTLQSMLQNLHA
                     KYGDNIPENIRVDFRKQSRHLMRYIDLLTFNGRTMVMFVIVLTGQVWAYYLYEIIVLN
                     IVLAIVMRKHEKMCASFLG"
     gene            complement(9125..9853)
                     /locus_tag="ACZPB4_10110"
     CDS             complement(9125..9853)
                     /locus_tag="ACZPB4_10110"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HIR1098599.1"
                     /translation="MDKFILITGGTKGIGKAVASCLGKAGYNLILTYASDQAAAEEVR
                     SELVGRFDIQVSILRADISDRNTIGVIDSFLEENRLRLDGLVFNAGMTCRDPFEELSF
                     EDWDRVFFANIHFPIFLLQKIVGRINKGGSIVFTGSLMGIQPHSVSLAYGVTKSAVHA
                     LVKNMVKFLVPYELRVNAVAPGFVDTEWQKTKPAEIRRNIENKVSLGRFCDPDELAEV
                     YKMLIENSYFNGEVVVVDGGYSYK"
     gene            complement(9865..10332)
                     /locus_tag="ACZPB4_10115"
     CDS             complement(9865..10332)
                     /locus_tag="ACZPB4_10115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylyltransferase/cytidyltransferase family
                     protein"
                     /protein_id="HIR1098600.1"
                     /translation="MFKDKTIVYTSGTFDMFHYNHLRMINYARSLADILIVGVSTDEL
                     VSSYKAKPIIPFHERLQIIEALKTPDIVIPQHSLDHTEIVKKLNIDAFVVGDDWFGKY
                     DYLKDLGVQVFYFPYGTGVSSSNLKKTIHDSYEANLTTQRQAKPETVKGSAAK"
     gene            complement(10501..11610)
                     /gene="pdxA"
                     /locus_tag="ACZPB4_10120"
     CDS             complement(10501..11610)
                     /gene="pdxA"
                     /locus_tag="ACZPB4_10120"
                     /EC_number="1.1.1.262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050570 - 4-hydroxythreonine-4-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_process: GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxythreonine-4-phosphate dehydrogenase
                     PdxA"
                     /protein_id="HIR1098601.1"
                     /translation="MEERLIKVGITHGDINGIGYEVILKTFSDTRMAELCTPIIYGSS
                     KIAAYHRKALELPPINMNIISHAEDAGVNRVNIINCVEDETKVELSKSTPVAGESAFK
                     ALEAAVTDMKRGVVDVLLTAPINKHNIQNEDFHFPGHTEYLEKCFGGLDKKALMILMK
                     DDLRVALVTGHIPLSQVASSINVGDIVNKLRIFNQSLKQDFGIVKPRIAVLSLNPHAG
                     DAGLLGTEEETIIIPAMQEAEKKGVMSFGPYAADGFFGSQMYDKFDGVLAMYHDQGLA
                     PFKTLAMDDGVNYTAGLPIVRTSPAHGTAYDIAGQNVASEESFRQALYAALDIYRNRL
                     RYQEATANPLRKQYFDRGGDNEKLDLTKDDDTDGL"
     gene            complement(11627..12664)
                     /locus_tag="ACZPB4_10125"
     CDS             complement(11627..12664)
                     /locus_tag="ACZPB4_10125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4837 family protein"
                     /protein_id="HIR1098602.1"
                     /translation="MKTRSLFIGMLLLLVLMGACNSGSVMTQATGFAYEVVVVMDQKD
                     WKGPAGEAIKSELASSVPGLPQAEPSLKITYVQPKDFTGLLRYVRNILVVTIDPTAYT
                     KVSVGYENNVWARGQVVVSLKAPNTESIVEYSKTHEKALVNFFVKVEMNRAIEQLQKE
                     YSMVVMDNLKSDLNVMLNAPANFTYYKDTTDFFWSSNNANTGRMDLIVYTFPYTDPNT
                     FTEEYLVAKRDSVLKANLPGSFPGSYMQTETRAGVEYTPITLNGKYCGVMRGLWRMQG
                     DMMGGPFVSHTRLDEKNHRVVVAEGFVYAPETDKRNFMRRIEAALFTLRLPGEFDEPV
                     TETLDIPKEKK"
     gene            complement(12681..13712)
                     /gene="rlmN"
                     /locus_tag="ACZPB4_10130"
     CDS             complement(12681..13712)
                     /gene="rlmN"
                     /locus_tag="ACZPB4_10130"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dual-specificity RNA methyltransferase RlmN"
                     /protein_id="HIR1098603.1"
                     /translation="MVDKRQLLGMTLEELKGVASEVSLPAYAAKQMADWIYKKKITRI
                     SEMTNIAVAKRALLEDSFEIGVYPPSEYQKSKDGTIKYLYAAGPGRFVESVYIPTDDR
                     ATLCVSSQVGCKMNCLFCMTGKQGFTANLTANQILNQIQSLPENDSLTNIVFMGMGEP
                     LDNVDELFKVLEILTAPYGYAWSPKRITVSTIGVTKGLKRFLEESECHLAVSLHSPYP
                     MERLSLMPVEKAFPAREVIDLIKQYDFSHQRRVSFEYIVFKNLNDSLKHAEALSCLLG
                     GIPCRVNLIRFHAIPNVSLETSDIAKMEAFRDFLNAKGVVCTIRASRGEDIFAACGML
                     STAKNVTFV"
     gene            complement(13849..15984)
                     /locus_tag="ACZPB4_10135"
     CDS             complement(13849..15984)
                     /locus_tag="ACZPB4_10135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SurA N-terminal domain-containing protein"
                     /protein_id="HIR1098604.1"
                     /translation="MATLEKIRSKAGLLVLVVGLALFAFIIGDFLNSGSTYFRQSQER
                     IAEIDGEVVKIQDYQGRVDEMAEMYKMQSGSASLPEEYMTQIRQSVFDAMVQEVVLDE
                     ATAKLGMGVSPEELFDMVQGENISPLIQQMQMFTNPQTGAFDKAALLNFLKQIDSDNI
                     ASYPADQQAQLIQAKNFWLFWEKNIKRQRLEQKYTTLLSKAISANSLDAKEAYNDNAE
                     NSDIIYAMQSYATIPDSTIEVSKSEIEKLYNQRKELYKQKESKVIKYIAVDIRPSKED
                     YDKAQAEIESLKEELATSERVADVVNENSEVPYVDAFFTEKALDPEMKQFATTSEVGA
                     VYGPVFENDKYRMFKLVDKTVAPDSVKVSHIMLAGKSEAETTALADSLMGALKGGANF
                     AELAKKYSADQAAENGGELGWFTEVTALRGVNDDFKKAVFSTPLNEVAVVKSLYGTHL
                     VKVTEKTGNVEKYKIADIDMTVSPSSKTYSNIYNELNQFVSKNNSMAKLEENAKEAGY
                     NLISGATVTTDDQLLGSIKNSRPVIRWAFQNDKGSISEIFECSDKFVVAAVEGSISEG
                     YRPVDMVAPALRAELAAQKKGDKIAQELAAKNLTSVEAYAETMGSSVDSVKFVNFGTR
                     RIAGIGIEPNLNAMVSMAQVDQVSAPVKGNNGVYVFKVYARNKDGKEFNEAEEIRALD
                     ASNAYRVGFQAIQSMVNNAKVEDNRIRFY"
     gene            complement(16081..17334)
                     /locus_tag="ACZPB4_10140"
     CDS             complement(16081..17334)
                     /locus_tag="ACZPB4_10140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HIR1098605.1"
                     /translation="MGTLTYILISLAFSAFFSGMEIAFISSNKLRFELDKKERSLSSK
                     ILGIFYRNPNLFISTMLVGNNIALVVYGLQMAIVLEPFIAKVVANEALIVFIQSVIST
                     ILILFAGEFIPKTIFKLNPNLSLNIFAIPLFIIYIILYPVSKFSSLLSFLILKLGGVK
                     NLKSSPQALGKVDLDYFIQQSLEDAPQNSDMDTEVKIFQNALDFSNVRLRDCIVPRTE
                     IVACDTSATMEELRSKFIETGLSKILVYNENIDNIIGYIHSSELFKNPEDWTQHIRSV
                     SIVPETMAANKLMKLLMQEKKSLAVVVDEFGGTSGIVTLEDLVEEIFGEIEDEHDMKS
                     HVAKKVSDNEYLLSGRMEIDTLNEMFGLDLPESDDYVTIAGFILHFYQKFPKLNETVQ
                     IDKYSFKIIKVTATKIELVRMKVGI"
     gene            complement(17336..18001)
                     /gene="lptC"
                     /locus_tag="ACZPB4_10145"
     CDS             complement(17336..18001)
                     /gene="lptC"
                     /locus_tag="ACZPB4_10145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015221 - lipopolysaccharide transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015920 - lipopolysaccharide transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter periplasmic protein
                     LptC"
                     /protein_id="HIR1098606.1"
                     /translation="MIGNRFHCKTENMGITTTFVVVVMLLLFSASCSKEHKEVVDVEF
                     DPDKTYTMKATDVSSLISDSGITRYRLKAKEWQIYGKAAEPHWYFPEGIYVEKFDTLF
                     QTEASIKADTAYYYDKKGLWELIGNVEVESLQGEHFETSQLFWDQKQEKVYSDKFMRI
                     EQEDKIITGIGFESNQDMTLYKIFNSQGIFPVSDAPADTTRTVQGDSARGDVSQIDSI
                     KSN"
     gene            complement(18004..19368)
                     /locus_tag="ACZPB4_10150"
     CDS             complement(18004..19368)
                     /locus_tag="ACZPB4_10150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HIR1098607.1"
                     /translation="MKIKVLLLALGCTMGTLGAYAQKGVDNGTQFGSGEDSVRCITNI
                     SLFVPYAKAGNFKDAYDFWKIVYDECPAATKDIYLYGVKIMGWKIAQEKDPAKKNALI
                     DDLMGVYDKRVKYFGNDRRYGKDWIVARKVQDYLAQTGDNADYNQAYTWLKEIVDEKG
                     ADTEALGLSLFSFSSMKKMLNDPNFKEQYIQDYLKVSAGLDAQLKAAQAANNQKEVNA
                     LTAYKSGVDNAFANSGAADCETLQNLYAAKIEENKDNLPYLKETISLLRRTGCQEIEA
                     YFLASDYAYRQEPSAEAAVGLGKKAVKIKDYDTAIKYFDEAANLETDATSKADDYYMI
                     ALLLFEQNAYSKARQYCQKALEVNPNYGNAYLLIGKMYAATSKSVFPNDGVLARAAYN
                     AAIDKFEKAKQVDPSVAEEANTLISSYRAHLPSTEEIFMHPDLEKGKPFTVGGWIGER
                     TTIR"
     gene            complement(19454..20737)
                     /locus_tag="ACZPB4_10155"
     CDS             complement(19454..20737)
                     /locus_tag="ACZPB4_10155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098608.1"
                     /translation="MLKINKVVIISFLIFTQLPLWAQNNTNSPYTRFGYGELADRSFG
                     AGRAMGGVGYGLRSSKQINPLNPASYSCMDSLTFLFDFGASGQVSWFYDGTNKQRQMN
                     GNVEYIAMQFPITRRLAMSIGLLPYSYVGYDFGESRTEGGLSWGESFSGEGGLSDAYL
                     GLSYDIWKKRLSIGLNAGFLFGNITHSRNLIFPSSTGADNVYRNQRYEIRDLKLDFGI
                     QYTHPLSKTEHVTVGFVYSPGKKLNTTVYDIQTVGSLSSTSGYTRNDTIKDYRFDMPN
                     SYGAGISYVKENRLTLAADFLYEDWANAYFDNEKGQFKNRTRVAAGAEFIPRYDNRNY
                     LGRIRYRAGFHYSNSYLRVSRSEENGYKGHGYNEYGASVGFGLPLIDNRSLVNLSFEY
                     VKIRPELRTMIDEQYFRFTVNYTFNELWFFKRKVD"
     gene            complement(20724..21551)
                     /locus_tag="ACZPB4_10160"
     CDS             complement(20724..21551)
                     /locus_tag="ACZPB4_10160"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III pantothenate kinase"
                     /protein_id="HIR1098609.1"
                     /translation="MRSFLFKKNFRGYTMFLRVISSFLFFFAENIREVNLIIEQGNTS
                     SKVAVYKNGHIEASFVYKQFGVSVVAALFEKYAFTQGILSTVIDTDDELIAYLKNKLQ
                     RFVFLDEHVALPIKVEYGTPKTLGKDRLAAVVGANYLRPGKNLLVIDAGTAITYEVIE
                     APGIFLGGNISPGMTTRFRALNHFTKKLPLVTEEDDIPLIGRSTETAIQAGVVNGIVY
                     EMDGYIDELKVKYPDLLVFLTGGHSFYFERRLKNSIFADINLVLTGLNRILEYNVEN"
     gene            21588..22634
                     /locus_tag="ACZPB4_10165"
     CDS             21588..22634
                     /locus_tag="ACZPB4_10165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004316419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2776 domain-containing protein"
                     /protein_id="HIR1098610.1"
                     /translation="MNYGISVLFRAIPLLMALFCFGYGFFVFNYGVDSSRFVAGPVVF
                     SLGFICIALFATAATIIRQIIHTYNNVARFALPILGYLSATITFLAGFILLMSSPAPA
                     DFVAGHVICGVGLITACVATTATASTRFTLIQMNAKSDDPRIPDKAFNFWQGVFLILV
                     ASFISIVAWIWAYRLLAHSDEHSQYFVAGHVMAGLACICSSLIALVATIARQIRNTYS
                     RLEKRLWHRFVILMGSISLIWGLFVLGDSDPANASTGYIMIGLGLVCYSISSKVILLS
                     KIWREEFKLANRIPLIPISTALFCLFLSAFLFEMAAEHSYYAIPARVLAGLGAICFTL
                     FSIVSILESGTSSK"
     gene            22978..23051
                     /locus_tag="ACZPB4_10170"
     tRNA            22978..23051
                     /locus_tag="ACZPB4_10170"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:23012..23014,aa:Thr,seq:tgt)
     gene            23180..23710
                     /locus_tag="ACZPB4_10175"
     CDS             23180..23710
                     /locus_tag="ACZPB4_10175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011965919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4199 domain-containing protein"
                     /protein_id="HIR1098611.1"
                     /translation="MEENKNLLLKGAMTYGLAMGIYWVVKYIFFIFSVSVPSLSLVYW
                     LLTLAVPFIAYYMTKRYRHDIGGRISFFHAWRFGTMLYFFAALIVSLEYFVFYQFIAP
                     PDFVANAIGQLTTVLKDSQVSSEMIDSLSKIRISPIHMAIQGIFNNVFYGIILSIPVA
                     ALLCRNNSTGSITENR"
     gene            23732..24682
                     /locus_tag="ACZPB4_10180"
     CDS             23732..24682
                     /locus_tag="ACZPB4_10180"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005677545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HIR1098612.1"
                     /translation="MDISVVIPLYNEAESLPELFSWIERVMKEHNYTYEVIFVNDGST
                     DNSWEVIEELKQRSPHVRGIKFRRNYGKSPGLHCGFQRAKGDVVITMDADLQDSPDEI
                     PELYRMITEDGYDLVSGWKKKRYDPLSKTIPTKLFNATARKFSGIKNLHDFNCGLKAY
                     KNVVIKNIEVYNDMHRYIPYLAKIAGFHKIGEKVVKHQARKYGTTKFGLDRFVNGYLD
                     LITLWFTSKFGKKPMHFFGLWGSAMFFIGFIALVIVLSMKLISMYSGDLRPLVTSSPY
                     FYISLTAMILGTQMFLAGFIGELISRNSPNRNNYKIEDEI"
     gene            24679..25200
                     /locus_tag="ACZPB4_10185"
     CDS             24679..25200
                     /locus_tag="ACZPB4_10185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HIR1098613.1"
                     /translation="MSFLELARKRCSIRKYAPKNVEQEKIDYILEAARLAPSAVNYQP
                     WYFVWVQSAEGKAKLQECYPREWFKQAPYYLIVCGDHQQSWKRGDHKDHMDIDTAIAT
                     EHICLAAAEQGLGTCWVCNFDTELCRKHFKIPETIEPVVLIPFGYPSDPALFDETPKK
                     RKPIEEIIKRESF"
     gene            25202..25768
                     /locus_tag="ACZPB4_10190"
     CDS             25202..25768
                     /locus_tag="ACZPB4_10190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005384 - manganese ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0071421 - manganese ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="manganese efflux pump MntP"
                     /protein_id="HIR1098614.1"
                     /translation="MLYIEVLLLAIGLSMDSLAVSVTGGAVLKNNCTAGNIIKIASVL
                     GIFQAGMTVIGYTMGLGFEKYICAFDHWIAFTLLLYLGGKMIYDSTKEEEEDGKFDPL
                     CNRTLCGLGIATSIDALAVGISLAILKSPLLLQASTIGVVTFAISAFGVYFGNRFGKR
                     IDLKLDLIGGLILIGIGTKILIEHLFFS"
     gene            25813..>26213
                     /locus_tag="ACZPB4_10195"
     CDS             25813..>26213
                     /locus_tag="ACZPB4_10195"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase domain-containing
                     protein"
                     /protein_id="HIR1098615.1"
                     /translation="MKSQQLRKLAPELDSLRLGSGWKIDELSKPQIIVESSYGHSHPG
                     SAHLDKLVDEAGIGIKEKGGRAANYFVTDICDGEAQGHDGMNYSLVSRDIMAAMMEIH
                     VKATPFDAGVFIASCDKSVPAHLMAIARLDMP"
BASE COUNT         7467 a         6451 c         5047 g         7248 t
ORIGIN      
        1 ggggctgggc agtatatgtt acttgaccca gtaagtaata ttgcgaatgg taaagccaca
       61 ctcaatgaaa aacgatattg gtaatgaccg aggcacccgc gtaatcattc aagcttttca
      121 ccaaccgttc ccggcaaagc gtcaactcgc tacgaagtac ggaggaagtc aatgagacat
      181 gaagcacctt atcacgtaca tatatattac gtgtgtactg catgatcgta ggccctaaaa
      241 cttctcccca cgcacgttgg acccggatct ccatcatttt ctcgtacaac tcggtattat
      301 cctcgaaaaa gtcacgaagc acttccccca atgtctgtgt atttcttctc tgcattctta
      361 ttcctccata ggttgtacct cgccacgttc cacacggaag agagcatagt catgattcat
      421 agccaataag atctcatcca gatacttccg gttcgtatcc gtaataaaaa tctgcccgaa
      481 gccattctcg ctgaccagtt tgatgatctg ctccacacgg ctagcgtcca gcttatcgaa
      541 aatatcatcc aacagcaaga taggtgtagt ctgtccccgt ttatttagga aagcgaactg
      601 agcgagtttc aaggcgatca gatacgtctt attctgtcct tgcgaaccaa cccggcgaat
      661 caggtacccg cccaacgtca tttccagctc atccttatgg ataccggaag aggtatagcc
      721 caatatacga tcccgttccc ggctcatcgc caatttaccg gcaagctccg tttcctccaa
      781 ttgcgagata taatgtagcc ctacctcctc ggcagagccg cagatcgtct ggtagtactc
      841 attaaagatc ggggtaaaat cctccaccag ttttttccgc ttctcgtaaa cgatttggcc
      901 gtacataccc agctgcatct ccaatacctc ataaagagag gcatccatgc tctgatcttt
      961 cagcaacgta ttccgttgga gcaacgcttt attatattgg ataagcgcat gcagataagg
     1021 cttgtcctgc tgcgagatga ttaagtccag aaaacggcgt cgctcatcgc ttcccccccg
     1081 gatcaagtcg gcatcagccg gagaaaccat gaccaacggt aataggccga tatgctcgga
     1141 cagcttgtcg tactccttct tattccgttt gaactgtttg cgttgcctac gccgcatggc
     1201 acagaaaatc tcctcctcac gtccctcata atcatagtta ccctgcacca cgcaaagatc
     1261 ttgatcactg tttattatct ggctatcagg cgtattgaca tgactcttgc aaaatgagag
     1321 ataatgaatg gcatccaata gattcgtctt ccccatcccg ttattgccga aaaagcaatt
     1381 catcttgggc gagaaaataa cctcggactg aagtatattt ttgtaattga gaacagaaag
     1441 cttctttagt atcatctaaa ccgtattaat cgtacaaaat taaaaaatat acttctaagt
     1501 atagattata tcagcaaaaa aaactacttt tgcgctttga atcgccaacc atatggtatg
     1561 gcttaaaatc agcgataaaa ttaataaata actataacac attatggcta ctaaagaaaa
     1621 ggacaccaac aaggagttag aagtagaaga gattgtctcc aaatcggagc aattcattga
     1681 aaacaattca aagaagatta tttacggtat aatagctgtc gcactcgttg ttggagctgt
     1741 tttgggaatc aagcatggtt atttagttcc tcaggagaaa aaagccgccg ccgccatgtt
     1801 caagggcgag caatacttcg ccagagattc tttcgccttg gctttaaacg gcaatggagc
     1861 tgactatgaa ggtttcgagg ctatcatcga ccaatatgga agcacggacg ccggaaactt
     1921 ggcgaaggct tacgcaggta tctgttacta caagatgggc gatacacaga aggcgctcga
     1981 tttattgaaa tctttcagcg gaaaggacca aatggtatct ccggcggtta caggcttgat
     2041 cggtgattgc tacgtgaaca tgggtaatac gaaagaagga atcagctatt tcgagaaagc
     2101 cgctaaggag gccgacaacg aggttatcag cccgatttac ttgaagaagg ccggtatcgc
     2161 ttacgagaac ttgaaagagt atgacaaggc tgtaaaggct tacacgacta tcaaggacaa
     2221 gtattacact tccatggagg catccgatat cgataagtat atcacccgtg cttcggcagg
     2281 aaaataaata aacagtatat tatatagtat aacagaggat gtctcggtca aacaaggcat
     2341 cctcttcttt taaagagaca agtatggcta cagcttatca gaatttatcc gagtacgatt
     2401 tcaacagcgt acccgatgct tcagagatga acatcggcat cgtagttgcg gaatggaaca
     2461 agaacattac cgagaagtta ttggaaggtg cttgcaacac gcttgaaaag cacggggtga
     2521 aaccggagaa catcgtagtt aaacgagttc cgggaagttt tgaactgact tttggagcca
     2581 aaagattggc cgagactaaa gaattagacg ccgtgatcgt tctgggatgc gtcgtaagag
     2641 gcgacacgcc acattttgat tacgtttgtt ccggcgttac tcaaggcatt acagaattga
     2701 atttaatgta cgatatccct ttcattttcg gcctgttaac taccgacacc atgcagcaat
     2761 ccgaggatcg tgcgggaggt agatatggca ataaagggga cgaggcagcg gttaccgcaa
     2821 taaaaatggt aaatttttct gcctaaacgc ttgcaggttt caaaataaat cgtacctttg
     2881 cactgcaatt aagaacaagg gggcagttac cagagtggcc aaatggggct gactgtaact
     2941 cagctggctt tcgccttcgg tggttcgaat ccatcactgc ccaccttttt aattcgcaac
     3001 atattattgc ggaagtagct cagttgatag agcattagcc ttccaagctg agggtcgcgg
     3061 gtttgagccc cgtcttccgc tctaggaaaa gaggaaaatc gaaaggtttt cctctttttt
     3121 ttatatcctc gtattactat atatccggga taatgtctac tttagccccc aatacaacaa
     3181 ataacaaaaa gagagatgaa gatagtgaaa gggatatacg tgttgctgac aatgttccta
     3241 ttgatgggat gcgctacggt aatgaatcct tataaaatgg acaaccggat gcataagata
     3301 gagctaggga tgaccaagca aaaggttata tcgatactag gaaaggattt tgagtcggct
     3361 ggcgcacgaa taaccccgga cggccccata gagagcatca gttataagac ggtcaccatg
     3421 acgatagccg actactctga aggctactac atcctaagct tcaagaatgg gatactggta
     3481 gaatggttca aggaaaagac accgatcaat aacaatacag cgaactaagg tctcctttta
     3541 ggctactaaa aacaaataag gcagatgcct ctgggcatct gccttcattc ttttacgatt
     3601 ataaactttc ttcgatacat gaatccggtt atgactgacc ggcctgccgt ggttttctaa
     3661 ctcggcctca cgactgcctt tccggttagc ctttatgtac tcgactaacg gatcttgctt
     3721 ttttctcttt gtcttcatag ctttattgct tttatatcgc tttcacgagc gcaaagatac
     3781 gaaaagaatt catttcacct cactatcgtc ccaagggtat tttcttttcg gatttctagg
     3841 gaaccagcct ttctgcacac gctcctcctg ctcgaaaatc tccttgatcg tccagaacga
     3901 tgagaaggcg aatacgccgc aaatagcgga cacaaacacg ctgtctataa acagggaggc
     3961 tatcactcct aaaatcccca agacaaggaa tatccaccag catttcgtcc cccaataata
     4021 ctcggccttc acgactaccg gatgaaacag accgataatc aaaaatgtaa cgataccgat
     4081 caacaaccca tcaaaattta tcatatccat atctgagtat ttatacttat tactattata
     4141 tgtaacaaat atacgaacaa tattccactt aactgatcat ttctttctat gaagagatag
     4201 aagcccctat tcgcaataat cgtctcacaa agatgaaacg atcttttcat atacgtgata
     4261 cgatcttttc acccttgtga tacgatcttt tcacataggt gaaaagatca agacctaaag
     4321 aagcttacac ttaaagtagc acaaaaaaaa gtcacatcca ttgttagtgg acatgacttc
     4381 tatattgttt tcaaataaga ttcttatctg ttgctttcct ccgcaggtgt agtagtagcg
     4441 ggagtttcct ctgccggaac tgccggttgt tgagccgtac caaagtccgg agcaatcgta
     4501 ttcggatcga tagagatagc gtcgtttact tgttgcttga tctcagattg agcggcatgc
     4561 tccgctctgg ggataaatgc ggtaatcaag atactcaata cgattacggt acccgccaaa
     4621 ctccaagtag ctttctccaa aaagtccgtg gtcttacgta cacccatgat ttggttagaa
     4681 gaagagaacc ctgaagccaa acctccacct tttgagttct ggatcaacac gatcaagatt
     4741 aatagtatag aggcaatcag gattaagata gaaataaata cgtacatctt agttttattt
     4801 tttagtgtta ataatcaact tttccaaaaa tctgatttgg tctgcaaagt aaacattttt
     4861 ttctggatat ttcaagctta agtttttaat aatttgcaaa gccttatcat atcgcttctg
     4921 ttttatataa atccgggcta aagtttccgt aaggcacgag tcttccagcg atttggactg
     4981 ctcatcatcc aaatctttca ccgactctgg agtctccgca cggctgtttt cctctcggat
     5041 ttccagcccg ctacccggca tacgctgttg gtcattttta atgaacgaat cgatcaagtc
     5101 gtgatgtcga agcctattct ccgcatcctc tccagatggc ttctcttctt cctctttcga
     5161 taatgaccaa aacatataat ctgacgatac cgatggctgg aacaggaacg gagcttcttt
     5221 cttaggctcc ggttcctcgt tacggttaga gaggaatgcg tctatcaagg agaaagtatc
     5281 ctcttttcgc atatccggct catgctccac acgggagttc aagccatatt tatctccctc
     5341 tatcagttgg aacagctttt tccgatccgg caagaatatc gccatcctct ccagctccga
     5401 ggtaaaactc atatcattta atacggccag attctttaga tacaacatcc gtgccacttg
     5461 aaaatacggg taatcctcca cgattcgtcg caactcaaga agagtcccct cggtcaattc
     5521 cgaaggctcc tccatcaaac gatataaatc ctccgccctc attctaccaa ttggcaaccg
     5581 tagcgttata gatttggtct actatttcct ctatgatttc ctcgcataat gttccctcta
     5641 cctgctgcgg catcaagtta ctgtcgaact cgcggtaagc ggagaacgac tgctcaaaat
     5701 cctcatccgg gttaacccgg ttggagtaac gaacccgcac cgtgatcgtc aacctcgtct
     5761 gcgaggcgat agcatcctcc ttcacggcca ttggagcgaa atcgtaacca gtgatctcac
     5821 cctccaactc aaggtcgcca ttgctcggaa ccagttgcag acgagtctga cggatgtaaa
     5881 tatccttcaa atcctccgta aactgcggcg caagggtcgg attcacgtag ggagcttggt
     5941 tcgtgaagtc acgaatcgta atggtcttca ccttcgtata atcgatagag gctccattaa
     6001 acttatagga aatagagcaa gccgtagcca ataccgtcaa aaatgagagt ataagccaat
     6061 tggctgccga caaacgtatg ttgacaatct tctttagcat attttattcc aaattgtatt
     6121 ccttgatttt tcgatataac gtacgctccg atatcttcaa gtcggccgcc gcgttcttcc
     6181 gtcgcccgtt atgcttctcc agagccttac ggatcatctc cttctccacc tcttccaagg
     6241 ataaagtctc ctcttccaca tcctcggcat cttggatcgt cgggtgcatg gcatgaaccg
     6301 ccgccggatg gatcggatgc gcataagggg tatcgtccgc caccgttggc atcgggatat
     6361 tccctcccat gatatcatgc actaatttct ttagctcgtt cacgtccttt ttcatatcga
     6421 acaagacttg ataaaggatc tcccgctcgc tgttaaatat cttttgatcc ggatcttgct
     6481 tcaccaatac cggatatttc tcaacgttca cgttcggcag ataaaggcgc aggacatccg
     6541 ccgttatatc ccgtgtctcc tcgattacgg agatacgttc cgtgatattt ttcaactcac
     6601 gcacgttacc cggccaacgg taagaaacca ataattgacg ggcctcatca tccaagcgga
     6661 tcggcggcat ccggtatttc tcggcgcaat cactggcgaa cttacgaaat aataagacga
     6721 tatcttccgg acgctcccgc aagggaggca cttggatagg caccgtattc aaacgatagt
     6781 acaaatcctc acggaattta ccttccgaaa ccgcctgcac taaattcacg ttcgtagcgg
     6841 caacgatacg cacgttcgtc ttctgtacct tggaggaacc gaccttgata aactcacccg
     6901 tctccaacac acgaagcaag cgtgcttgcg taggagttgg cagctctcct acctcatcca
     6961 agaagatcgt tccaccgtcc gctacctcga aatacccttt acggtcggct aacgccccgg
     7021 taaaagaacc tttctcgtgc ccgaaaagct ccgagtctat cgtcccttcc ggaatggcgc
     7081 cacagtttac ggctatatat tgtccatgct tacgctgact gttctgatga ataatttgag
     7141 ggaaagtctc ctttccgaca ccactctctc ctgtaataag aacagataag tcggttggcg
     7201 ctacctggag cgcaacatcg atcgcacgat ttaatccggg gttattacca ataatcccaa
     7261 aacgctgttt tatctgttgt acatcaacct tcatcactct ttcactttta aaatctgtaa
     7321 ttatttcagt tactctgcca aaattacaaa tcttaattca aactaccact attgataaca
     7381 gattctatcg gtcgtttctt attttttagc accatatgta cgtttataca agaactcggc
     7441 aagatccttg tcttccggga tggcggcgat ctcttccggc gagataggct caccgatata
     7501 tacatccgct ttctttccac gcttattgaa agcctctgta ggaatacgca aggtacgtat
     7561 ttgccagctg atattcccta gccaatagaa aaaatgggta ttttggaaat caaaataaac
     7621 agggtatacc ggtgctttcg ccttacgaac taagcggatc acgctatgcg cccacgataa
     7681 atcccgtacc tgtttctctt ttttattata aaatgagatc gctccagcag ggaagaaacc
     7741 catcggatga ccttctttca agcgttgcag ggatagtcga acgccattga cattcgccgg
     7801 attcgcccct cgcttgtggg aatcgggcac cacggatatg aaattatcct ccatcgcccc
     7861 gatcttggtc aagatgccat tcaccatcac cttaaagtcc ggacggcggg aagcgaaaat
     7921 atcaatcagc atgattccat ccaacgaccc gatcggatgg ttggaaacgg taacaaaagc
     7981 cccttccggc agatgatcta aaatctcctt attatgaacc tcatagctga gatcgataat
     8041 ggggtcatgc aataaagcgg aagtaaactc agcgccccgt aaatgacaat tccgggcatg
     8101 taccttatta accagatcca cacgtaagca ctttatcagc aacttaccta accatgtccc
     8161 cactcgcccc ttgaagaacg gggccatctc ttgcaaatcg taaatgtcaa caacactctt
     8221 cttcatactt tatcctaaaa acgaggcaca catcttctca tgtttcctca tcactatcgc
     8281 tagtacgatg ttcaacacga tgatctcgta taggtaataa gcccagacct gtcccgttag
     8341 tacgatcaca aacataacca tcgtccggcc attaaaggtc aacaagtcta tgtaacgcat
     8401 taaatgacga ctctgtttac gaaagtccac acggatattc tccggaatat tatccccata
     8461 cttcgcatgc aaattttgta acatactctg taaggtaggc gtagccttca cttgcaacat
     8521 cgtataccaa cgatataaga agtagaaaaa cttgttaatg ccatacttca tctccttatg
     8581 tttcgcctcc acctgctcca aagactgaaa ctccgagcct ttatccttac tgataaaata
     8641 aaggtgaagc gtcttataat aatccgtgat attcgcttgg actaaatgag acaaaccgga
     8701 taagaccgcc aaggcaaaga accaatccgt accgtaatca tgagacaaac gaagagcgaa
     8761 tccgatatag atcgaagcga accagatatc cccggcgaat ccgtccaaga tacgcccgat
     8821 agcggacttg attcctgtaa gacgtgccag ctgcccatcc acgcagtcga ggatattggc
     8881 aaataccaac aataatatac cgcagatatt atatgtcaaa ttatcgtgat aaaacataaa
     8941 tccgaccgcc gcacccacga agatcgagat aaccgtaatc atattcgggg taatccccgt
     9001 gcctcgcaac atacgagcaa tacgaaatcc tatcggacga taaaaaattc ggtctatctt
     9061 attttctgtt tctatcgact ttaacgatgc ttcgtattcc ttatccaact cgctcatttg
     9121 tttcttattt atacgagtaa ccgccatcca caacgactac ctcgccatta aaataactat
     9181 tctctatcaa cattttataa acttccgcca attcatccgg gtcgcagaac cgtcccaaag
     9241 agaccttgtt ctctatattc cgacggatct cggcaggctt tgttttctgc cattccgtat
     9301 cgacaaaacc gggagccacg gcattcacac gcagttcata gggaactaag aacttcacca
     9361 tgtttttgac cagcgcatga acagcacttt tcgtcacccc atatgccaaa gataccgaat
     9421 gaggctgtat tcccatcaag gaacccgtaa acacgatact tcccccctta ttaatccgtc
     9481 caacaatctt ctgtaaaagg aagatcggga aatggatatt agcaaagaaa acccggtccc
     9541 aatcctcgaa tgaaagttcc tcaaaaggat cccgacaggt cattcccgca ttgaacacaa
     9601 ggccgtccaa acgtagccta ttctcctcca agaaagaatc gataaccccg atcgtattcc
     9661 gatccgagat atcggcccgc agaatagaaa cctgtatatc gaaacgcccc accaactcgc
     9721 tacgtacctc ctcggccgcc gcttggtcgg aagcataagt cagtataagg ttatatccgg
     9781 cctttcctaa acaggacgct accgcctttc ctatcccttt tgtcccaccg gtaattaaaa
     9841 taaatttatc catgaaactg atcgttattt agcggcagat cctttcactg tttccggctt
     9901 cgcctgacgt tgggttgtca gattcgcctc ataagaatca tgtatcgttt ttttcagatt
     9961 cgaggaggaa acccccgttc cgtaagggaa ataaaatacc tgaacgccta aatctttcag
    10021 atagtcgtac tttccgaacc agtcatcacc taccacgaaa gcgtcgatgt tcagcttctt
    10081 cacgatttcc gtgtgatcca aggaatgttg tggaataacg atatcgggag tcttcaacgc
    10141 ctcgatgatc tgcaaacgtt catggaacgg aatgatcggc ttcgctttat aagaagagac
    10201 caactcatct gtactaaccc cgacgatcaa tatatccgcc aaactacggg cgtaattgat
    10261 catcctaaga tgattataat ggaacatatc aaacgttccg gatgtatata ctatcgtttt
    10321 gtctttaaac ataatcgtaa ttttcgtttt aaaccgcaaa cttacgcaaa cttttcctat
    10381 cttaaaagtt taaaaccaaa aagcgtccca cgccccatac aaaaatgtca tgtcaataac
    10441 atccattcgt tattaacatg acattttatg tatttattga aacttgtcag gaaagatcta
    10501 ctataatccg tccgtatcgt cgtctttcgt caaatccaat ttctcattat ctccccccct
    10561 atcgaaatat tgcttacgca acgggttggc ggtagcctcc tgataacgca accggttccg
    10621 gtagatatcc aacgccgcat ataaggcttg gcggaacgac tcttccgagg ccacgttctg
    10681 cccggctatg tcataagcag ttccgtgtgc cggagaagtc cgtacgatcg gcaatcctgc
    10741 cgtatagttc accccgtcat ccatcgccaa cgtcttgaaa ggagcgagcc cttgatcatg
    10801 atacatcgct aagacaccat caaatttatc atacatctgc gaaccaaaga aaccgtcagc
    10861 cgcataaggg ccaaatgaca ttacgccttt tttctccgcc tcttgcattg ccggtatgat
    10921 aatcgtctcc tcttccgtac ccagcaatcc ggcatcaccg gcatgagggt ttaaggaaag
    10981 aaccgcgata cgtggcttca caataccgaa gtcttgcttt aacgactgat tgaaaatacg
    11041 cagcttattc acgatatcgc ccacattgat ggaagacgca acttgcgaca atggaatatg
    11101 ccccgtcacc aaagcgacac gaagatcatc tttcatcaag atcatcaagg cttttttatc
    11161 caagccaccg aagcatttct ccaaatactc agtatgcccg ggaaaatgaa aatcctcgtt
    11221 ctggatatta tgtttattga tcggggcggt aagcagtaca tccactactc cccgcttcat
    11281 atccgtaacc gccgcttcca acgccttgaa agccgactca ccggcaaccg gcgtagattt
    11341 cgacaactcc accttggtct cgtcctccac gcagttaata atgttcaccc ggtttactcc
    11401 cgcatcctcc gcatgtgaaa taatattcat attgatagga ggaagctcca atgccttccg
    11461 gtgataagcg gctatcttgg acgagccata gataatcggc gtgcaaagct ccgccatgcg
    11521 ggtatcggaa aaggtcttta atatcacctc atagccgata ccatttatat ctccgtgggt
    11581 gatccccact ttaatcagtc gttcttccat atattttgtt tgtttattac tttttctctt
    11641 tggggatatc caatgtctca gttaccggtt catcaaattc acccggcaaa cgtaacgtaa
    11701 ataaggcagc ttctattcta cgcatgaaat tacgcttgtc tgtctccgga gcatacacaa
    11761 atccctcggc tacaaccaca cgatgattct tttcatccaa gcgagtgtgg cttacgaacg
    11821 ggcctcccat catatcgcct tgcattctcc acaaaccgcg catcacgcca caatatttac
    11881 catttaaggt tattggcgta tactccactc ccgcacgcgt ttctgtttgc atataggaac
    11941 ccgggaacga acccggcaga ttcgccttca atacagaatc tcgtttagcg accagatatt
    12001 cctccgtaaa cgtattcgga tcagtataag ggaaagtata tacgattaag tccatacggc
    12061 ctgtgttagc gttattggaa gaccagaaga aatctgtcgt atccttatag tacgtgaagt
    12121 ttgccggagc gtttaacatc acgttcaggt cgcttttcag gttatccata accaccatac
    12181 tatattcctt ttgtaattgc tctatcgcac gattcatctc tacctttacg aagaagttga
    12241 ccaacgcctt ctcatgggtc tttgaatact cgacgatcga ctccgtatta ggagctttca
    12301 gcgaaacaac cacctgtcct ctagcccaga cattattctc gtaacctaca gaaactttcg
    12361 tataagcggt gggatctatc gtaaccacta atatattcct tacataccgt aacagacctg
    12421 taaaatcctt tggttgtacg taggtaatct tcaaagaagg ctcggcttgc ggcagtccgg
    12481 gcaccgaaga ggccaactca gactttatgg cttctcccgc agggcctttc caatcctttt
    12541 gatccataac cacgacaacc tcatatgcga agcccgtagc ttgagtcatc acagaacccg
    12601 aattacatgc tcccatcaaa acaagaagca gcaacatacc gatgaataaa gaacgtgttt
    12661 tcatacccgt gtgttttata ttatacaaat gtaacatttt ttgcggtaga aagcattcca
    12721 caagcggcga aaatatcctc ccctcgtgat gcccttatcg tacatacaac tcctttggcg
    12781 tttaagaaat cccggaacgc ctccatttta gcgatatcgg aagtctctaa agacacattc
    12841 ggtatcgcat gaaaacggat caagtttacc cgacaaggaa ttccacctaa taaacaactc
    12901 aaagcttcgg catgtttcaa gctatcgttc aaatttttaa aaacaatgta ctcaaaagag
    12961 acacgtcgtt gatgcgaaaa atcatattgt ttgattaaat cgatcacctc cctcgctggg
    13021 aatgcctttt caaccggcat caaggaaaga cgttccatag gatagggcga gtgcagactt
    13081 acggccagat gacattcgct ctcctctaaa aagcgtttca aacctttcgt cacaccgatg
    13141 gttgaaaccg tgatacgctt cgggctccac gcatatccat acggggccgt gagtatttcc
    13201 aaaaccttga aaagctcgtc tacgttatcc agtggctccc ccattcccat gaaaacgata
    13261 ttcgtcaatg aatcgttttc cggcaaagac tggatctggt tcaatatctg gttcgctgtc
    13321 aggtttgccg tgaagccttg ttttcccgtc atacaaaaca agcaattcat tttgcatccg
    13381 acttgagaag agacgcaaag agtcgcccga tcatccgtag gaatataaac agactcaaca
    13441 aaacgccccg gtccggcagc atatagatat ttgatcgtac cgtctttcga cttttgatac
    13501 tcagatggcg gataaacccc gatctcgaat gaatcctcta ataaagcacg tttggctacc
    13561 gctatattcg tcatctccga aatccgggtt attttcttct tataaatcca atcggccatt
    13621 tgcttagccg catatgcggg aagactcacc tcagacgcta cacctttcag ttcctccaag
    13681 gtcatcccta ataattgtct tttgtcaacc atgctatcga tattttctta ttcgcgaaag
    13741 tacgagaaat attccacaaa ataaagatcc cctgttttgc cgtcaaaata aatatatctt
    13801 gacgacaaaa caggggatct tttttatctt aagtataaat actctttatt aatagaaacg
    13861 gatacggttg tcttctacct tagcgttgtt gaccatagat tggatagctt ggaatcctac
    13921 acgatatgcg ttcgaagcat ccaacgcacg gatttcctca gcctcgttga actccttacc
    13981 atctttattt cttgcgtata ctttgaacac atatacaccg ttgttacctt taaccggagc
    14041 acttacttgg tcaacttgag ccatagaaac catagcgttc aagttcggtt cgataccgat
    14101 accagcgata cggcgagtac caaagttcac gaacttcaca gagtctacag aagaacccat
    14161 cgtttcagca tatgcctcaa ctgaagttaa attcttagca gccaattcct gagcgatctt
    14221 atcgcctttc ttctgggcag ccaattcagc tctcaaagcc ggagcgacca tatcaaccgg
    14281 acgatacccc tcggaaatac ttccttctac agcagccacg acaaatttat cactacactc
    14341 gaagatctca gagatagaac ctttatcgtt ctggaacgcc caacgaatta ccggacgtga
    14401 attcttgata gaacctaaca actgatcatc tgtagtaacc gttgcacctg aaatcaagtt
    14461 ataaccggct tccttcgcat tctcctccaa tttagccata gagttgttct tagatacgaa
    14521 ctgattcaac tcattgtaga tgttgctata ggtcttagag ctaggagata cagtcatgtc
    14581 gatatctgcg atcttatatt tttcaacatt tcctgttttc tctgttactt ttacaaggtg
    14641 agtaccatat aaagatttca caaccgctac ctcattcaat ggagttgaga agacagcctt
    14701 cttaaaatca tcattcacac ctctcaaagc ggtaacctct gtaaaccaac ctagttcacc
    14761 accattctcg gcagcttggt ctgctgagta tttcttagct aattcagcga aattagcgcc
    14821 acctttcaac gcccccatca agctatcagc caaagctgtt gtctcagcct cagatttacc
    14881 ggccaacatg atgtggctaa cttttactga gtccggagcg accgtcttat cgactagctt
    14941 aaacattctg tatttgtcat tctcgaatac aggaccataa acagcgccaa cctcagaagt
    15001 cgtagcgaat tgtttcatct caggatccaa agccttctcc gtgaagaaag cgtcaacata
    15061 aggaacctca gagttctcgt ttactacatc agccactctt tcagacgtag ctagctcctc
    15121 tttcaagctc tcgatctcgg cctgtgcctt atcataatcc tctttactcg gacggatatc
    15181 tacggcgata tatttaatta ccttagattc tttttgttta taaagctcct tgcgttggtt
    15241 atacaatttc tcgatctcgc tcttgcttac ctcaatcgtt gaatccggaa tcgtagcata
    15301 tgattgcata gcgtaaatga tatccgaatt ctcggcatta tcattataag cttccttagc
    15361 gtccaatgaa ttcgcggaaa tagccttact caataatgtc gtatattttt gctccaaacg
    15421 ttgacgtttg atgttcttct cccagaacaa ccagaagttc ttagcttgaa tcagctgtgc
    15481 ctgttgatct gccggatagc tagcgatatt atcggaatcg atttgtttca agaaattcaa
    15541 caaagcggcc ttatcaaaag caccagtctg aggattcgta aacatttgca tttgttggat
    15601 caacggagag atattctcac cttgaaccat atcaaacaat tcttccggac ttactcccat
    15661 acctaattta gcagtagcct cgtccaacac gacctcttgt accatcgcat cgaatacgga
    15721 ctggcgaatc tgtgtcatat attcctcggg caggctggct gaaccggatt gcatcttata
    15781 catctcggcc atctcatcaa cgcgaccttg ataatcttga atttttacaa cctctccatc
    15841 aatctcggcg atccgttcct gtgattgcct aaaataagta gaaccagagt ttaaaaagtc
    15901 tccaatgata aaagcgaaca atgccaaacc caccacgagt accagcagtc ctgctttgct
    15961 tctaattttt tccagcgtag ccatttatct ttattatttt ttaaagttta ttatttcaca
    16021 ttttaagggc acaaagatat gaaaaaaagg aaattccaca gcatataatc ctttttttta
    16081 tcaaatccct actttcatac gtacaagttc gatcttcgta gccgttactt tgattatctt
    16141 aaacgaatat ttatcgatct ggacagtctc gttcaatttc gggaattttt gatagaagtg
    16201 caagataaaa ccggcgatgg tgacataatc atccgactca ggaagatcca acccgaacat
    16261 ttcgttcaag gtatcaatct ccatcctacc cgacagcaaa tactcattgt ccgatacttt
    16321 tttagccaca tgcgacttca tatcgtgctc gtcctcaatc tctccgaaaa tctcctccac
    16381 caaatcctca agtgtcacga tacccgacgt accgccaaac tcatccacga caacagccaa
    16441 gctcttcttc tcttgcatca gcagtttcat cagtttattc gctgccatcg tctccggaac
    16501 gatcgatacg ctacggatat gctgggtcca atcctccgga ttcttgaaaa gctcggaaga
    16561 atggatatat ccgataatgt tgtcaatatt ctcgttatac accaatattt tcgaaagtcc
    16621 tgtctcgata aacttagaac gcaattcctc catcgtagcc gacgtatcac aggctacgat
    16681 ctccgtccgg ggcacgatac aatccctcaa acggacattc gagaagtcta aggcattctg
    16741 gaaaatctta acctccgtat ccatatccga attttgaggt gcatcttcca gactttgctg
    16801 tataaaataa tccaagtcta ccttgcctaa tgcctgaggt gaacttttca agttcttcac
    16861 gccccctaac ttcaaaatca aaaaagatag cagggaagag aacttggaga ccggatacag
    16921 gatgatatat ataataaata atggtatcgc aaatatattg agtgataaat taggattcaa
    16981 cttaaatatg gtcttgggaa taaactcccc ggcaaacaag atcaagatcg tagatatcac
    17041 ggattggata aaaacgatca atgcctcatt cgcaaccacc ttggctataa acggctccaa
    17101 tacgattgcc atctgaagac cataaacgac caacgcaata ttatttccta ccaacatggt
    17161 agagataaac aaatttggat tacgatagaa aatacccagt atcttactgg atagactacg
    17221 ttccttctta tccagctcga aacgaagctt attggaggag ataaaagcga tctccatccc
    17281 ggaaaagaat gcggaaaatg cgagggaaat taaaatataa gtcagcgtcc ccaccttaat
    17341 tactttttat tgaatctatt tgtgacacat ctccccgggc actatccccc tgaactgtcc
    17401 gtgtcgtatc ggccggagca tcgctcaccg ggaaaatacc ttgtgagtta aatatcttat
    17461 acagagtcat atcttggttc gactcaaagc ctatgcctgt tatgatctta tcttcttgct
    17521 cgatacgcat aaacttatca gaataaacct tctcctgctt ctggtcccag aacaattggg
    17581 aagtctcaaa atgctcccct tgcagacttt ccacctctac attaccgatc agctcccaaa
    17641 gccctttttt atcataataa taggctgtat ccgccttaat actcgcttct gtctggaata
    17701 aggtatcgaa cttctccacg tagatcccct cggggaaata ccaatggggt tccgccgcct
    17761 tcccgtaaat ctgccactct ttcgctttca agcgatatct cgtgatacca gaatcggaga
    17821 tcaaggatga cacatccgta gccttcatcg tataagtctt gtccggatca aactcaacat
    17881 caaccacctc cttatgttcc ttactgcaag aggcagaaaa caaaagaagc ataacaacca
    17941 ccacgaaggt agttgttatg cccatatttt ccgttttaca atgaaaacga tttcctatca
    18001 taattaccga atcgttgtac gctctccgat ccaaccaccg acagtgaaag gtttgccctt
    18061 ctccaaatcc gggtgcatga agatctcctc cgtagaagga aggtgagcac gataagatga
    18121 tatcaaagta ttagcctctt cagcaacact cggatctacc tgtttcgctt tctcaaattt
    18181 atcgatagcg gcattataag cagctcttgc caacactcca tcattcggga agacagattt
    18241 agaagtagcg gcatacatct tgccgatcaa taaataagca ttaccatagt ttggatttac
    18301 ctccaaagct ttctggcaat attgtctagc cttcgaataa gcattttgct caaacagcaa
    18361 caatgcgatc atataataat catcagcttt tgaagtcgcg tccgtttcta aattcgcggc
    18421 ctcatcaaag tatttaatag ccgtatcata atcctttatc ttaacggctt tctttcctag
    18481 cccaacagct gcctcggcac taggttcttg acgataagca tagtctgatg ccaaaaagta
    18541 agcctcgatt tcttggcaac ctgttcttct caacaaagat atagtctctt tcaaataagg
    18601 taagttatcc ttattctcct cgatcttagc agcatacaaa ttctgcaaag tctcgcaatc
    18661 ggcagcacca ctatttgcaa aggcattatc aacaccactc ttatatgcgg tcaaggcatt
    18721 cacttctttt tgattgtttg cagcctgcgc agcttttaac tgagcatcca agccagcaga
    18781 aaccttcaaa taatcttgaa tatactgctc tttgaagttc ggatcgttaa gcattttctt
    18841 catagaagag aaactaaaca aggagagacc tagagcctcc gtatcagcac ctttctcatc
    18901 aacgatctcc ttcaaccaag tataggcctg attatagtcg gcattatcgc ctgtttgcgc
    18961 taaataatct tgcacttttc gagcaacgat ccagtctttt ccataccggc gatcatttcc
    19021 aaaatatttc acacgcttgt cgtaaacccc catcaaatca tcaataagag cattcttctt
    19081 agcgggatct ttctcttggg cgatcttcca gcccataatt ttcacaccgt acaaatagat
    19141 atcttttgta gcggcaggac actcatcgta cacgatcttc cagaaatcat aggcatcttt
    19201 gaagtttccg gctttcgcgt aaggaacgaa caagctgata ttggtaatac aacgcacgct
    19261 atcctcaccg gaaccgaact gtgttccatt atctactcct ttctgcgcat aagcgcctaa
    19321 cgtacccata gtacatccaa gcgctagtaa taaaactttg atcttcatat ctctttctat
    19381 taaagttagc tataatattt atattccttc aaaaaagtat catactcatt agaccctttc
    19441 ggccattccc ggtttaatcc acttttcgtt taaaaaacca taattcgtta aatgtatagt
    19501 tcacagtaaa ccggaaatac tgctcatcaa tcattgtacg taattccgga cggatcttca
    19561 cgtattcaaa tgacaggttc actaatgaac ggttatcgat caatggaagc ccaaaaccga
    19621 cactcgcccc atattcatta taaccatgtc ctttataacc attttcctcg gagcggctga
    19681 ctcttaagta cgaattgcta taatgaaaac cggcacggta tctgatacgc cccaaataat
    19741 tacgattatc ataacgaggt ataaactcgg caccagccgc cacacgtgta cgattcttga
    19801 attggccttt ctcgttatca aaataagcgt tcgcccagtc ctcatacaag aaatcagcgg
    19861 ctaacgtcaa ccggttctcc ttcacataag agatacctgc tccgtaagaa ttcggcatat
    19921 caaaccgata atccttaatc gtatcattcc tcgtatatcc agatgtagaa gacaaagagc
    19981 caacagtctg aatatcatac acagtcgtat tcaacttctt tccgggagaa tagacgaaac
    20041 ctaccgtgac atgctccgtc ttactcaaag gatgcgtata ttgaatacca aaatctaact
    20101 ttaaatcacg aatctcataa cgttggtttc tatacacatt gtccgcccct gtcgaactcg
    20161 ggaaaatcaa gttgcgggaa tgtgttatat ttccaaataa aaatccggcg ttcaaaccaa
    20221 tggaaagacg cttcttccaa atatcatagg agagccctaa ataggcatcg cttaagccac
    20281 cttcgccact aaagctttct ccccaactta aaccgccctc ggtacggctc tcgccgaaat
    20341 catatcctac atatgaataa ggtaataaac caatactcat cgctaaacgc cgggtgatcg
    20401 gaaattgcat ggcgatatac tccacgtttc cattcatctg tcgttgcttg ttcgtaccgt
    20461 catagaacca agacacctga ccggacgcac caaaatcaaa aaggaatgtc aacgaatcca
    20521 tgcaactata agatgctgga tttaatggat ttatctgttt agaggacctt aatccataac
    20581 cgactccacc catcgccctt ccggcaccaa aagatcgatc cgccaactct ccatatccaa
    20641 atcgcgtata aggcgagttc gtgttatttt gagcccacaa tggcaattgt gtaaagataa
    20701 gaaaacttat tattactacc ttattaattt tcaacattat actctaagat tctgtttaat
    20761 cctgtcaaca ctaaattaat gtctgcaaag atggagtttt ttagccgtct ttcaaaataa
    20821 aacgaatgac cgcctgttaa aaaaaccaaa agatccggat attttacttt cagctcgtca
    20881 atatatccgt ccatctcgta aacaatccca ttcaccacac ccgcttggat agccgtttcc
    20941 gtacttctcc cgataagcgg tatatcatcc tcttccgtta ccaaaggcag tttcttcgta
    21001 aaatggttca acgctcgaaa acgggttgtc atccccggag agatattccc tcccagaaag
    21061 atacccggcg cttctatcac ctcatacgtg atagcggtac cggcatcgat aaccagcaga
    21121 ttttttcccg gccgcaaata attcgccccc acgacagcgg ccaaacggtc cttgcctagc
    21181 gttttcggcg tcccatattc caccttgatc ggtaaagcta catgttcatc cagaaagaca
    21241 aaacgctgaa gcttattttt tagataagcg atcaactcat cgtccgtatc tatcaccgtc
    21301 gataaaatgc cttgcgtaaa agcgtacttc tcaaaaagag cagcgaccac agatacaccg
    21361 aattgcttgt atacaaaaga agcctctata tgcccatttt tatacacagc gacctttgat
    21421 gacgtgttac cttgttctat aataagattc acttctctga tattttccgc aaagaaaaac
    21481 aaaaatgatg aaataacacg caaaaacatc gtataacctc taaaattctt cttgaacaaa
    21541 aaggatcgca tctctgtttg aagaaaaatc taaataaaaa acaagttatg aattacggga
    21601 ttagtgtctt attcagggcg attccattgc taatggccct cttttgtttc ggttatggat
    21661 tttttgtctt taactatgga gtggactcca gcagattcgt cgccggacct gtcgtattct
    21721 ctcttggctt tatttgtata gccttgttcg ctacggcagc gaccattatt cgtcaaatta
    21781 tccatacata taataatgta gccagattcg ccttgcctat ccttggatat ctctcggcaa
    21841 ccatcacttt tctggcgggc tttatcttac tcatgtcctc accggcgcca gcagactttg
    21901 tcgcgggcca tgtcatttgc ggggtgggcc ttataaccgc atgcgtagca acaacggcta
    21961 ccgcctctac ccgattcacc ttaatacaaa tgaacgccaa aagcgacgat cccagaatac
    22021 cagacaaagc gttcaacttt tggcaggggg tattcttgat ccttgtagca tcatttatat
    22081 ccatagtcgc atggatttgg gcttaccggt tgctagcgca tagcgacgag cattcccaat
    22141 actttgtcgc cgggcatgtg atggccggac tagcatgtat ttgcagcagc ttaatcgctt
    22201 tagtcgccac gatcgcccga caaataagaa acacatattc ccgattggaa aaaaggctat
    22261 ggcaccgttt tgtcatcctg atgggatcta tcagtctgat atggggcctc ttcgtattag
    22321 gagatagcga cccggctaat gcctcaaccg gatatatcat gatcggcctt ggattagttt
    22381 gctatagtat ctccagcaag gtgatcttgc tgtctaaaat atggagggaa gaattcaagc
    22441 ttgccaaccg gattccatta attcctatat ccacggcttt attctgcctt ttcctctccg
    22501 ctttcctttt cgagatggcg gccgagcata gttattatgc cattcccgca cgggtattgg
    22561 ccggactggg agcgatctgc tttacgttgt tctccatcgt cagcatattg gaaagcggaa
    22621 cctcttccaa gtaaactgtt ttttcatcgt gatgaaaata ctttttcttc acggtgaaaa
    22681 tactttttct tcacggtgaa aatatttttt cctcacaatg aaaaaatcaa cattctttga
    22741 taaaccatcg gccacaacac ataaaacatt ctttaacact accaaaagca taaggttttc
    22801 aattctttat aaacaattat catcccaaga gtaagaaaac gcttgcaaag taaaaaataa
    22861 tatctacttt tgcacccggg taagtcctac acggcatgct ccctcggaat cccccagggc
    22921 ttgaccgcag caagggtact tggtcgtagc ggcgcgatgt agtaagctta cccacctgcc
    22981 tctttagctc agttggccag agcacgtgat ttgtaatctc ggggtcgttg gttcgaatcc
    23041 gacaagaggc tcagataaga cacatcttaa agaaggaagc ttataagtag gcttcctttt
    23101 tcgcatttta ggcataatat agttgcgcat ttgcattaat atattaattt tgctgataag
    23161 aattcaaaac tgcagcatca tggaagagaa taagaattta cttttaaaag gcgctatgac
    23221 ttatggtttg gccatgggta tatattgggt agtgaaatac atctttttca tcttcagcgt
    23281 ttccgtcccc tccttaagtc ttgtctattg gctattgacg ctcgccgtcc ctttcatcgc
    23341 ctactacatg acgaaaagat atcggcacga catcggtgga aggatcagtt tctttcatgc
    23401 atggagattc ggcacgatgt tgtatttttt cgccgcattg atcgtctcgc ttgaatactt
    23461 tgtcttttat cagttcatcg ccccgcctga tttcgtggca aatgcgatcg ggcaattaac
    23521 gactgtacta aaggatagcc aagtcagctc ggagatgatc gactcgctca gcaagattcg
    23581 tatctcgcca atccacatgg ccatacaagg aatatttaat aacgtatttt acggcatcat
    23641 actttctata ccggtagcgg ctctcttgtg caggaacaat tcgacaggtt ccatcactga
    23701 aaaccgctaa aaagttaatt acagacaaat aatggacata tcagttgtta tcccgttgta
    23761 taacgaagcc gagtctttac ccgagttatt ctcgtggata gagcgggtga tgaaagaaca
    23821 taattatacc tatgaagtca ttttcgtgaa tgacggcagt acggataatt cttgggaagt
    23881 gatcgaggag ttgaagcaac gttctccaca cgtccgggga atcaagttcc gtcgcaacta
    23941 cggtaagtcg ccgggattgc attgcggatt ccaacgggct aaaggtgacg tggtcattac
    24001 catggacgcc gatctgcagg acagcccgga tgagataccc gaactttacc ggatgatcac
    24061 cgaagacggg tacgatctgg tatccggctg gaaaaagaaa agatatgacc cgttgtctaa
    24121 gacgatcccc acgaaattat tcaacgcaac agctcgtaaa ttctcgggaa taaagaactt
    24181 acacgatttc aattgcggat tgaaagcgta taagaatgtt gtcattaaaa atatagaggt
    24241 gtataacgat atgcaccgtt acatacctta tttagctaag attgccggat ttcacaagat
    24301 tggcgagaaa gtagtgaaac atcaagcccg caagtacgga actactaaat tcgggttgga
    24361 tcgcttcgtg aacggttatc ttgatttgat cacgctttgg tttacttcca aattcggaaa
    24421 gaaaccgatg cacttcttcg gtttatgggg aagcgctatg ttcttcatcg gttttatcgc
    24481 tctagtaatc gtactcagca tgaaattgat ctcgatgtac tctggagatc taagaccttt
    24541 ggttacaagt tccccttatt tctatatttc attgacagcg atgattctgg gaacccagat
    24601 gttcctagcg ggctttatcg gggagttgat ttcccgcaat tctccgaatc gcaataacta
    24661 taaaatagag gatgagatat gagtttccta gaattagcga gaaaacgttg ttctatccga
    24721 aagtatgccc ccaaaaatgt ggagcaagaa aagattgatt atatcctaga agcagctcgt
    24781 ttggcccctt cggcggtaaa ttatcaacct tggtattttg tatgggttca aagcgcggaa
    24841 ggaaaagcta aattacaaga atgctatccc cgggaatggt tcaagcaagc gccttattac
    24901 ttgatcgttt gcggagatca tcagcaatct tggaaacggg gcgatcataa ggatcatatg
    24961 gatatcgata cggctatcgc cacggaacac atttgtttag ccgctgccga acaaggattg
    25021 ggaacttgtt gggtttgcaa tttcgacacg gagctttgcc ggaaacattt taaaatcccg
    25081 gaaacgatcg agcctgttgt attgataccg ttcggctatc cttccgaccc ggcattattc
    25141 gatgagactc caaagaaacg taagcccata gaagaaatta ttaaacggga atcattctag
    25201 tatgttatac attgaagttc tgctactagc gatcggctta tccatggata gcctagcagt
    25261 atcagttacc ggcggcgcag ttcttaagaa caactgcacc gccggtaata ttattaagat
    25321 agcgagcgtg ctcggtatat tccaagccgg aatgaccgtg atcggttata cgatgggatt
    25381 aggattcgaa aaatacattt gcgccttcga ccattggatc gcatttaccc tcttgcttta
    25441 cttaggtgga aaaatgatat acgatagcac gaaggaagag gaggaagacg ggaaattcga
    25501 tcctctatgt aaccggacat tatgcggatt gggaatagcg acaagtatcg atgccctcgc
    25561 cgtaggaatc tctctggcga tcttaaaatc accactcttg ctgcaagcct cgactatcgg
    25621 tgttgtcacc ttcgctatct ctgccttcgg tgtctatttc ggtaaccgat tcggcaagag
    25681 aatcgacttg aagctggacc tcatcggagg tttaatctta atcggtatcg gtacaaaaat
    25741 tttaatagag catttattct ttagctaggg ataccttatt gaataaataa ccttatacat
    25801 taattaatag acatgaaaag ccagcaatta cgaaaactag cgccggagct ggattcactc
    25861 cggctaggca gcggttggaa aatcgacgaa ttgagtaaac cgcaaatcat tgtagaaagc
    25921 agttacggac atagccatcc gggaagcgcc catctggata aattggtgga cgaggccgga
    25981 atcggtataa aggaaaaggg gggacgtgcc gcaaactact tcgtcaccga tatttgtgat
    26041 ggagaggcgc agggacacga tggtatgaac tactcattag tctcccgtga tatcatggcc
    26101 gccatgatgg aaattcatgt aaaagcgact cctttcgacg ctggtgtctt tatagccagt
    26161 tgcgacaaat ccgtccctgc gcatttgatg gcgatagccc ggctagatat gcc
//
LOCUS       DBMDTB010000056        26151 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_666_length_26151_cov_13.114587, whole genome shotgun sequence.
ACCESSION   DBMDTB010000056 DBMDTB010000000
VERSION     DBMDTB010000056.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 26151)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 26151)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26151
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_666_length_26151_cov_13.114587"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(133..1836)
                     /locus_tag="ACZPB4_10200"
     CDS             complement(133..1836)
                     /locus_tag="ACZPB4_10200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase family glycosyl hydrolase"
                     /protein_id="HIR1098616.1"
                     /translation="MEQKNKMVIYQVFPRWFGNLRPSPVMNGSLAENGVGKFSAFTPL
                     ALSKIKELGVTHVWYTGVIEHATKTDYTMFGIRKDHSAVVKGKAGSPYAIKDYYDIDP
                     DLADNIQNRMSEFEDLVKRTHEAGMKVIIDFVPNHVARQYFSDAREPFVEDLGQTDNV
                     SKAFDVNNNFYYLPGQTLTLRFDPQREEDFAYSEFPAKVTGNNHFDAYPSQNDWYETV
                     KLNYGVDYMHGGACHFNTIPNTWEKMLEILLFWADKGVDGFRCDMAEMVPVEFWNWVI
                     PQVKKVRDVIFIAEVYNPDEYRNYIYTGHFDYLYDKVGLYDTVRAVMCGQAPASNISH
                     CWQSLEGIQKNMLNFLENHDEQRVASDFFAGDARPGIPGMIVSAAMNTNPVMIYSGQE
                     LGERGMDAEGFSGRDGRTTIFDYWSVESLRNWNNNGLFDGAKLTPAERSLREMYAKLL
                     NVVRSEPVIVEGAFYDLMYANSGNPYFNPNRQYAFLRKWKNEVLLVVVNFDRADQCVW
                     VNIPVEAFKALDFEDNKPAELTDLLTGETTISTLTDAYPYQVKLPAYSGKMLKFSFLH
                     K"
     gene            complement(1896..2732)
                     /locus_tag="ACZPB4_10205"
     CDS             complement(1896..2732)
                     /locus_tag="ACZPB4_10205"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HIR1098617.1"
                     /translation="MAEETNHKPYRLGLALSGGGAKGFAHIGVFRMMEECALRPDIIV
                     GTSAGALMGALFADGYSAAEIQELFTGREFSEFAQLQIPKAGLFDSKRFRYFLRRHLR
                     TKNIEDLQIPLVVVATDLDNGESHEFRSGPIVEAVTASCSIPIIFSPVVINGVHYVDG
                     GLFHNFPVSIIREECERIIGVNVSPLIPQKYKQTIFHIAERSYHYMFRANTLEDREMC
                     DVLIEAEEFGLYKTFDLENVDVICNIGYSAAARCFEKVLDENKYETLVKAIAARKKGL
                     MP"
     gene            2899..5103
                     /locus_tag="ACZPB4_10210"
     CDS             2899..5103
                     /locus_tag="ACZPB4_10210"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-translocating pyrophosphatase"
                     /protein_id="HIR1098618.1"
                     /translation="MITSIFWIIPLASVLALAFAWFFFRQMMKESEGTELMKKIASFV
                     REGAMSYLKQQYKVVASVFVVLVILFSIMAYGFHVQNEWVPIAFLTGGFFSGLAGFLG
                     MKTATYASARTANAARTSLNKGLQVAFRSGAVMGLVVVGLGLLDISFWYILLNAFIPD
                     EALDPTHKLTIITTTMLTFGMGASTQALFARVGGGIYTKAADVGADLVGKVEAGIPED
                     DPRNPATIADNVGDNVGDVAGMGADLYESYCGSILATAALGAAAFVSSGSVELQYKAV
                     VAPMLIAAVGIILSIIGIFAVRTNENATIKQLLKALAIGTNLSSVLIAISTFGILYVL
                     GMENWFWIGCSVIVGLLVGIVIGQATEYYTSQSYKPTRLVSESGLTGPATVIISGLGL
                     GMLSTAIPVLAVVVGIICSFLFASGFDFTNVGMGLYGIGIAAVGMLSTLGITLATDAY
                     GPIADNAGGNAEMCNLGKEVRKRTDALDSLGNTTAATGKGFAIGSAALTGLALLASYV
                     EEIKIGLLRLGENVLNFTDGRSIEISKASFSDFMVYYDVTLMNPKVLAGMFLGSMMAF
                     MFCGLTMNAVGRAAGHMVEEVRRQFKEIKGILTGEAQPDYARCVEISTKGAQHEMVLP
                     SVLAIIAPILTGLIFGVTGVVGLLIGGLSTGFVLAVFMANAGGAWDNAKKFIEEGNHG
                     GKGSEAHKATVVGDTVGDPFKDTSGPSLNILIKLMSMVAIVMAGLTVAWSLF"
     gene            5249..7441
                     /locus_tag="ACZPB4_10215"
     CDS             5249..7441
                     /locus_tag="ACZPB4_10215"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005637168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004356 - glutamine synthetase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase III family protein"
                     /protein_id="HIR1098619.1"
                     /translation="MSISRFNAVEKASNRKAVEAVTPEHKVSEYYGENVFNRKAMQKY
                     LSKETYKALTHAIDNGTPIDREIANHVAAGMRMWALEKGVTHYTHWFQPLTDGTAEKH
                     DAFVEHDGNGGMIEEFSGKLLVQQEPDASSFPNGGLRNTFEARGYSAWDPSSPAFIVD
                     DTLCIPTVFIAYTGEALDYKTPLIRSIEVLGEAAKDVYRYFDEDVNKIITYLGWEQEY
                     FLVDEDLYSARPDLSLTERTLLGHESAKNQQLDDHYFGAIPSRVQEFMKDLETECYKL
                     GIPVKTRHNEVAPNQFELAPIYEECNLANDHNQLLMSVMKRVSRRHNFRVLLHEKPFN
                     GVNGSGKHCNWSMGTDKGVNLFSPGKDREDNLRFITFVVNTIMAVYKYNALLKASIAS
                     ATNAHRLGANEAPPAIISTFLGTQISEILDKFENSSIEDAIEVDDKKGLHLGFGQIPE
                     LLLDNTDRNRTSPFAFTGNRFEFRAPGSSVNCGSAMLALNSAVAYQLQQFKKDVEALQ
                     AEGKSKEVAIFKVLKAYIKESKPIRFDGNGYSDEWKEEAAKRGLDCQNSVPLQYDAYL
                     KPESIEMFTSTGVLTQKELEARNEVKWEVYIKKVQIEARVLGDLSLNHIIPVAVRYQS
                     VLLDNIAKLKETFGDDPEFRDMSEEPRRLVRKIAGHICAVTKKVDEMVEARKKANRLT
                     DMREKAIAYHDSVAPYLDEIRDHIDDLELMVDNQMWPLPKYRELLFIR"
     gene            complement(7549..8436)
                     /locus_tag="ACZPB4_10220"
     CDS             complement(7549..8436)
                     /locus_tag="ACZPB4_10220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM barrel protein"
                     /protein_id="HIR1098620.1"
                     /translation="MMITRRNFLKAGAAVAALSVVPNGFASILAKKEKAIGVQLYSVR
                     DDLKTDFDGTMKALVDIGYKRMEAAGYRDGKFYGKSPAEMKKYLADLGARMVGSHTGS
                     GLLAEGDTKGWDFWKKNAADTAEVGCKWIVQAGYPSKDIKSLSDVKRLADQFNKCGEI
                     AKANGLRFAFHNHVDEFHELEGKIPFDVMIENTDKGLVTFQIDTAQLVYGGFKCHDYV
                     NRYPGRFANWHLKDANADGKGSTEMGAGIVDFKSLFAVAEKAGLEDYFIEQERYNMTP
                     LQAMKHDYDFLMNASYVKW"
     gene            8511..9839
                     /locus_tag="ACZPB4_10225"
     CDS             8511..9839
                     /locus_tag="ACZPB4_10225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HIR1098621.1"
                     /translation="MQGTKNLTEGVISRQLFNLAMPIMGTSFIQMAYSITDMAWVGRL
                     GSEAVAAIGAVGILTWMTNSISYLNKVGSEVSVGQSIGAQNVEDARGFASHNLTIALI
                     LSLCWGFLLFVLAHPIIGFYKLEEPITLNAVEYLRIVASAFPFIFLSAAFTGIHNAAG
                     LSKIPFYISGTGLLLNMVLDPLFILGFHLGTAGAAWATWISQAVVCGLFVYQLKCRNK
                     LFGGFPFFVRLKERYTKRIFQLGLPVALLNTFFAIINLFMARTASTYGGHIGLMTLTA
                     GGQMEAIAWNTSQGFSTALSAFTAQNYAARKKERILTAYHTTLKMTSIIGVLCTLLFV
                     FYGSEVFSLIVPEQAAYEAGGIFLRIDGYSMIFMMLEITTQGMFYGTGRTVPPAIISI
                     SCNTLRIPLAIGLAAAGLGITGVWWAISLSSMLKGVVAFIWFSILQKKIL"
     gene            9910..11190
                     /locus_tag="ACZPB4_10230"
     CDS             9910..11190
                     /locus_tag="ACZPB4_10230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase family
                     protein"
                     /protein_id="HIR1098622.1"
                     /translation="MDNKFKPETLCVQAGWQPKKGEPRVLPIYQSTTFKYETSEQMAK
                     LFDLEESGYFYTRLQNPTNEAVAAKIAALEGGVAAMLTSSGQAASFFAFFNICEAGDH
                     IVSATSIYGGTYNLLAVTLKKLGIECTFVDQDASEEEISKAFRPNTKAMFGEMISNPG
                     VMVLDVEKFARIAHNHGVPLIVDNTFATPINCRPFEWGADIVTHSTTKYMDGHATSVG
                     GCIVDSGNFDWEAHAEKFPGLCQPDPSYHGLTYTKAFGKLAFITKATSQLMRDLGAIQ
                     SPQNAFLLNLGLETLHLRVPQHCKNALAVAQWLQKCDKVAWVHYPELEGNPYHELAKK
                     YLPNGSCGVLSFGLKGGREVAIKFMDSLKLAAIVTHVADARTCVLHPASHTHRQLSDE
                     QLIEAGVAPDLIRFSVGIENADDIIADIEQALNK"
     gene            complement(11294..12448)
                     /locus_tag="ACZPB4_10235"
     CDS             complement(11294..12448)
                     /locus_tag="ACZPB4_10235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family protein"
                     /protein_id="HIR1098623.1"
                     /translation="MKILFIIQGEGRGHLTQALSLRQKLMAEGHEIVGVLVGKSPARR
                     LPDFFLNKILSPVYPFESPNFLPTAKNKQVSLMRSVLYNVLRLHKYMGSIRYIDRMIR
                     QTDADVVVNFYELLTGLTYLILRPKATMVCIAHQYLFLHPDFVFPKQSTLSLASLRFF
                     TRLTAIGSVKKLALSFRKMREAPLGGIVVVPPLLRQEVLDAVPSNGSYLHGYLLNSGF
                     SEEIRSWHSRHPSVPMHFFWDKKDQRAEVKIDDCLSFHQLDDTLFLRYMSGAKAYATT
                     AGFESVCEAMYLNKPVLMVPTHIEQACNAYDASLSGAGVVADCFDLDVLLSISESHVE
                     NSVFRHWVKQADWLILREFREDLLREEHPVTSLGRITTNWVARLGRFLPI"
     gene            complement(12445..13215)
                     /locus_tag="ACZPB4_10240"
     CDS             complement(12445..13215)
                     /locus_tag="ACZPB4_10240"
                     /EC_number="3.6.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008758 - UDP-2,3-diacylglucosamine
                     hydrolase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-2,3-diacylglucosamine diphosphatase"
                     /protein_id="HIR1098624.1"
                     /translation="MILRKYYPTIVLSDIHLGSEHSRTEEVTRFLKHVDCDRLILNGD
                     IIDGWQLKKSGKRWKQKHTDFFKVLMKMMEKRGTEIIYVVGNHDDFLDSLAPFKFSNI
                     SIVKDYLLKTRQGKRYFVTHGDIFDTVTTHMRWLAMLGDVGYTFLLWLNKVYNHRRER
                     QGKPYFSLSQEVKHRVKSAVSYISEFEKELVRLAEAKHLDGIICGHIHQAASVWYGNV
                     HYLNSGDWVESMTALVEDEQGEWDIVTYNNVQLYADAV"
     gene            complement(13375..15531)
                     /locus_tag="ACZPB4_10245"
     CDS             complement(13375..15531)
                     /locus_tag="ACZPB4_10245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HIR1098625.1"
                     /translation="MKVYQTNEIKNISILGSSGSGKTTLAEAMLYEGGVIKRRGSVEA
                     GNTVSDYFPVEKEYGYSVFSTVFSVEWQDRKLNFIDCPGSDDFVGGAVSALNVTDTAL
                     MVLNAQYGVEVGTINQFRYTEQFHKPVIFVVNQLDNDKADYEGTIAQLKDRWGSKIVP
                     IQYPISCGSSFNAVVDVLKMKMYRWKPEGGVPDVLEIPAEEMDKAMELHQALVEAAAE
                     NDDTLMEKFFEEGALSEDDMRAGIRAGLVTRGMFPVFCVCAGRDMCVRRTLEFLGNVV
                     PCTDKMPRLITTEGVEVTPDSNGPTSLFFFKTTVEPHIGQVSYFKVISGKVKEGDDLM
                     NADRGSKERIAQLFAVAGQTRTPVTEMVAGDIGATVKLKDVRRGNTLNGKGCDYRFDF
                     IKYPDPKYRRAIKPVNEADAEKMMEILIRMREEDPTWVIEQSKELKQTIVSGQGEFHL
                     RTLKWRIENNDKLPIEYLEPKIPYRETITKAARADYRHKKQSGGAGQFGEVHLIIEPY
                     YEGMPAPDTYRFGGQEYKMNVRDTQIIDLDWGGKVVFVNCIVGGAIDARFLPAILKGI
                     MARMEQGPLTGSYARDVRICVYDGKMHPVDSNEISFMLAGRNAFSTAFKEAGPKILEP
                     VYDVEVSVPADYLGDVMSDLQGRRALIMGMNSEKGFEKLLAKVPLKEMSNYSTSLSSI
                     TGGRASFTMKFASYELVPADVQEKLLKAYEATQSEE"
     gene            15722..16849
                     /gene="hemW"
                     /locus_tag="ACZPB4_10250"
     CDS             15722..16849
                     /gene="hemW"
                     /locus_tag="ACZPB4_10250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HIR1098626.1"
                     /translation="MAGLYIHVPFCAKRCLYCDFFSNTEMKYKEPYINALIKEMELRK
                     GYIGNEALETIYFGGGTPSQLDEKDFGKIFEAIYRHFDVAEQMEITLEANPDDMKREY
                     VSLLRNYPFNRVSMGVQSFHPEDLRFLNRRHDRQQAIKAVELCKEYGITNISIDLIYG
                     LPNQTQQAWEENLRQAIRLDVPHLSAYHLIYEEGTALYKLLEAGKVTPINEELSVSFF
                     STLIDRLAEAGYLHYEISNFTRPGFFSKHNSSYWTGKKYLGLGPSAHSYNGIDREWNP
                     SSLPIYIDGIENGHPTIESEDLDLCTRYNDFIITGLRTMWGVSFADIQTKFGRKLLSY
                     CQKQAQPHINQGLLLQTDDKLILSKSGIFVSDGIMSDLLWV"
     gene            16967..17566
                     /locus_tag="ACZPB4_10255"
     CDS             16967..17566
                     /locus_tag="ACZPB4_10255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HIR1098627.1"
                     /translation="MQHQKQQTVPYLYIISGCNGAGKTTASFTILPEMLKCREFVNSD
                     EIAKGLSPFNADSIAVAVEASRIMYKRIKELIGAGETFAMETTLATRSVANLIREAQR
                     EGYYVTLLYFWLNTPDLAVERVKMRVAAGGHNIPEATIRRRYEAGIHNLFELYLPISD
                     YWMITDNSMSPMEVIAKGFKNDKREVYNLDIFTKLEHHE"
     gene            17559..17726
                     /locus_tag="ACZPB4_10260"
     CDS             17559..17726
                     /locus_tag="ACZPB4_10260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098628.1"
                     /translation="MNEQEVREFEENIVKGANIAFQRLVNQKKKEDGELVFSRNGHIF
                     RVKAVDLDKIY"
     gene            complement(17888..20047)
                     /locus_tag="ACZPB4_10265"
     CDS             complement(17888..20047)
                     /locus_tag="ACZPB4_10265"
                     /EC_number="3.4.14.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008239 - dipeptidyl-peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0070009 - serine-type aminopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S46 family peptidase"
                     /protein_id="HIR1098629.1"
                     /translation="MKKLFLSVAAAILAFPVLADEGMWLLPLLKQQKFAEMQALGLRL
                     SDQEVYSAEAPSLKDAVVRFGGGCTGEMISPDGLVLTNHHCGYSSIQRHSTLEHDYLT
                     DGFWAMSRDKELPNPGLTVTFIDKIDDVTDYVRTELKKITDPNSMEFLSAKYLNGLAK
                     AKVGEKFLQDNPGTEVEIKAFYGGNKYYMFTKKIYSDVRLVGAPPSSIGKFGADTDNW
                     MWPRHTGDFSLFRVYADANGNPAPYSETNVPLRPKRWLKLSLKGVEENDYAMIMGFPG
                     RTNKYYTSWEVAERRDIDNAVRINIRNLRQEAMLEEMLKDPQVRIQYASKYAGSTNAY
                     KNAIGSNWAINKRNFEQVKNDEQDRLIAWSKKMCEPAYPEALLTLEQIVNDRKDLRFR
                     SWMLDEALSRGIEFSKVPTDIETVCEALEGKDRSEQQKQVTQLERAFHRFADKDYAPM
                     VDKKIAKVMLKEYRRLVAPKSQPAYFSVIDSKFKGDVDKFVDYLFDKSIYGSEKNFNA
                     FKEHPSVKTLREDPMILFAQSVKDEKKALDKALADFDAGYAIAHRAYVKGLLAMYGDL
                     ASFPDANSTLRLTYGQVKGYSPRDCDYYGHQTTLDGVMEKEDSTNWEFVVSARLKELY
                     QAGDFGPYKMPNGKMPVAFCATTHTTGGNSGSPVLNGQGELIGINFDRNWEGVGGDIQ
                     YLPDYQRSIIVDIRYVLFVIDKYAGAGYLLNEMEFSR"
     gene            complement(20044..20517)
                     /locus_tag="ACZPB4_10270"
     CDS             complement(20044..20517)
                     /locus_tag="ACZPB4_10270"
                     /EC_number="3.6.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0050355 - inorganic triphosphate
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HIR1098630.1"
                     /translation="MAIEIERKFLVSGDFLPEAVSSTRIVQGYICSQPGRTVRIRIRG
                     EEGFLTIKGASDEKGLSRYEFEQKIPLVDAERLLELCEPGAIDKVRYLVPRGSHTWEV
                     DVFHGANEGLILAEIELSSEDEPFEKPAWLGKEVSGDRRYYNSMLTKHPFNSSNT"
     gene            complement(20507..21589)
                     /locus_tag="ACZPB4_10275"
     CDS             complement(20507..21589)
                     /locus_tag="ACZPB4_10275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2027 domain-containing protein"
                     /protein_id="HIR1098631.1"
                     /translation="MSIQIGDKVRFLNSVGGGVVRGFRGKDQVLVEDEDGFEVPALIK
                     ECVVVGGNDMQVHSSNRPKVQAPVETPSPKKPEPKEEKVEETPEGERLNVYLAYLPVD
                     PKAFQQCGYETYFVNDSNYYLFFNYMNRTNNSWTSRYNGIIEPNTKIFLEEFGKPELN
                     DLERICVQLIAFKKDKPYSLKNAVSVELRLDTVKFYKLHCFMENDFFEEDALIYPIIR
                     NDLPERELLVSAAELKEAMQQKVREERRVPRQIVKKKPTNSAILEIDLHITELLDNTN
                     GLSNADMLTYQLGKFREVMDQYALNNGQKIVFIHGKGDGVLRKAIEKDLKTHYKQHYF
                     QDASFREYGFGATMVTIKADTSKHGH"
     gene            21715..>22898
                     /locus_tag="ACZPB4_10280"
     CDS             21715..>22898
                     /locus_tag="ACZPB4_10280"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_function: GO:0051075 - S-adenosylmethionine:tRNA
                     ribosyltransferase-isomerase activity [Evidence IEA];
                     GO_process: GO:0008616 - tRNA queuosine(34) biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosylmethionine:tRNA
                     ribosyltransferase-isomerase"
                     /protein_id="HIR1098632.1"
                     /translation="MKTQEIRIEDYNYSLPDERIAKFPLPKRDESKLLLYRNGEISES
                     IFKHITDYLPQNSLMVFNNTRVIQARLLFQKETGARIEIFCLEPIEPHDYALIFQETR
                     RCSWTCLVGNLKKWKEGTLSKTIFIKDQPVVLTADKKKSHGDTHLIEFTWDNETYTFA
                     DILDAAGVLPIPPYLHRETEKSDLQTYQTVYSKIKGSVAAPTAGLHFTSEVLADIDAR
                     GIGREEVTLHVGAGTFKPVKSDTIEGHEMHTEFISVRRSSIERIKSNLGNIIAVGTTS
                     VRTLESLYYMGVILDNNPEATSEDLVVKQWMPYDMNNNRLTAERSLQNILDYLDKHDA
                     DTLVTATQIIIAPGYEFKIVKGIVTNFHQPKSTLLLLISAFVKGNWKSIYEYALEHDF
                     RFL"
     assembly_gap    22899..22998
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <22999..24966
                     /gene="porE"
                     /locus_tag="ACZPB4_10285"
     CDS             <22999..24966
                     /gene="porE"
                     /locus_tag="ACZPB4_10285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PorE family type IX secretion system protein"
                     /protein_id="HIR1098633.1"
                     /translation="HFTIYVLFLLIVSSLYSCKSAKLSDAEEKQRIGEYYEAAAIYRK
                     VYTKTSPKKRDLRGYIAYRMAECNRLINNTAKATSAYMNAIRYDYPDSTVYLRMGQML
                     QKTGRYPEAIKNYDIYMENDPSNLLAINGIQGCELAPGWKKNPTRYEVRRMDKFNSRR
                     GEFSPMLAGDKYDQLYFASSRSKDKDAKVSAITGQNNNNLFLVKQDEKGAWLAPVELE
                     DEVNTEYDEGTPSFSPDGNTMYYTYCAQDPEGPRTAEIYISTRSSAKWGKGTRATIVK
                     DSVTALGHPSISPDGKYLYFVSDAVGGFGGKDIFRARVAGNDFGPMENLGEEINTPGD
                     EMFPYVRDSVTLYFASNGHPGMGGLDLFKATQDSTGKWNVENLGAPINSMGDDFGITF
                     AGKEERGFFCSNRNDARGYDHIYSFELPTITIFIEGIVNDVDEYPIEDATVRIVGKDG
                     LNVKVPVKKDGTYRVELERDIRYVMMASARGYLNQNYELHTGPEEKNETYIVDFFLSP
                     ISKPVVIDNIFYDFDKATLRPESKKALDEMIKMLNDNPNVTIELGAHTDRKGTDQYNE
                     RLAQRRAQSVVDYLIAGGIEAARLEAKGYGESVPKTINKKMAKQFDFLKEGDVLTEEF
                     ILALPPEQQEIADQINRRTEFKVLRTNYNLF"
     gene            complement(24958..25326)
                     /locus_tag="ACZPB4_10290"
     CDS             complement(24958..25326)
                     /locus_tag="ACZPB4_10290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098634.1"
                     /translation="MEVIKKQRLAVCRILLDVVEGACEVRDPDLIMRTRHYPALQREM
                     CFADRDWEEARDLSVLACLVLSKELHYKVKMMIGLVAHDLYSRESSVSYQQRLSFDVL
                     MSAIDWPVSFKEITLFAPSK"
     gene            complement(25867..>26151)
                     /locus_tag="ACZPB4_10295"
     CDS             complement(25867..>26151)
                     /locus_tag="ACZPB4_10295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HIR1098635.1"
                     /translation="AGDINKVAAKVVSPTSGIVMEVYTNEPGLQFYAGNSMTKAGDKG
                     KLGVVYPHRGALCLETQHYPDSPNQPSFPSVILRPGEKYTSECIYKFSVE"
BASE COUNT         7194 a         6590 c         5582 g         6685 t
ORIGIN      
        1 gggcaagtat gttaagttac tttgccattt cacttaagtt acttgcccga tgaagctaga
       61 tgtcccgtat caaccaccta actccaccaa cgaattatct atacagcaca cctaaacttt
      121 tcaagaaagc tcttatttat ggagaaaaga gaactttagc atcttaccgg aataagcagg
      181 gagtttcact tgataaggat aagcgtctgt tagcgtactg atagtcgttt ccccggttaa
      241 caagtcggtc aattcagccg gtttgttatc ctcaaaatca agagccttga atgcctcgac
      301 cgggatattt acccatacac attggtcggc acggtcgaaa ttcacgacaa ccagaagtac
      361 ctcgttcttc catttgcgca agaacgcata ctgacggttc ggattgaaat aaggattacc
      421 ggagttcgcg tacatcaaat cataaaacgc tccctcgaca ataaccggct cggatcgtac
      481 cacattcaat aacttagcgt acatctcacg caacgagcgt tctgccggcg ttaatttagc
      541 cccatcaaag agtccattat tattccagtt tcgcaaactc tcgacgctcc aataatcgaa
      601 gatggtcgta cggccatcac gtccactgaa accttccgca tccattcctc tttcgccaag
      661 ttcctgacca ctatagatca taaccggatt tgtattcatg gcagcggaga caatcatgcc
      721 cggaataccc ggacgagcat cccccgcaaa gaaatcagaa gcgacacgct gttcatcgtg
      781 attctccaag aaatttaaca tatttttctg gattccctcc aacgattgcc aacaatgcga
      841 tatattacta gccggagcct gtccgcacat caccgcacga accgtatcat aaagaccaac
      901 cttgtcatac aaataatcaa agtgtcccgt ataaatataa ttcctatact catccggatt
      961 atacacctcc gctataaaga tcacatcacg caccttcttc acctgaggaa tcacccagtt
     1021 ccaaaactct accgggacca tctcagccat atcacaacga aaaccatcca cccccttatc
     1081 agcccagaac aacaagatct ccaacatttt ctcccacgta ttgggaatgg tattgaaatg
     1141 gcaagcacca ccgtgcatat aatccacgcc gtagttcagc ttcaccgtct cataccaatc
     1201 gttctggctt ggataggcat cgaaatgatt gttaccggtc accttcgccg gaaactcact
     1261 ataggcaaaa tcctcctcac gctgcggatc aaaacgaagc gtcaaggttt gccccggaag
     1321 ataataaaag ttattattca catcaaaagc cttggacaca ttatccgttt gacctaagtc
     1381 ctccacgaaa ggttcccgtg cgtccgagaa atattgacgt gctacatggt tgggtacaaa
     1441 atcgataata accttcatcc cagcctcatg cgtacgtttc accaaatcct cgaactcact
     1501 catacggttc tggatattat ccgccaaatc cggatctata tcatagtaat cttttatagc
     1561 atatggagat ccggccttac cttttactac ggcagaatgg tctttccgga tgccaaacat
     1621 ggtgtaatcg gtttttgtag cgtgctctat cacccctgta taccatacat gagtaacacc
     1681 tagttctttg attttggata aagccaaagg agtaaaagcc gaaaacttac ccactccatt
     1741 ctcggctaaa ctaccattca ttacaggaga tggtcgcaga ttcccaaacc aacgcgggaa
     1801 tacctgataa attaccatct tgtttttttg ttccattgcg ttcatctata tataaagttt
     1861 ttgtgggaaa gcgctttgtc cagacagacg atttgtcacg gcatcaggcc tttctttctt
     1921 gccgcgatcg ctttcaccaa ggtttcatat ttattctcat ccaacacttt ctcaaagcaa
     1981 cgggcagcgg cggaatagcc aatattacaa atcacgtcta cattctcaag atcgaatgtc
     2041 ttatataagc caaactcctc cgcttctatt aagacatcac acatctctcg atcctccagc
     2101 gtatttgccc ggaacatata atgataagag cgctcggcga tatggaatat ggtctgctta
     2161 tatttttgcg ggatcaacgg gcttacgttc accccaataa tacgctcaca ttcctcacgg
     2221 atgatggaga ccggaaagtt gtgaaataat cctccatcca cataatgaac gccattgatg
     2281 actacaggac tgaaaataat cgggatacta caagaagctg tcaccgcctc aacaatagga
     2341 ccactcctaa attcatggct ttcgccatta tccaaatcag tcgcgacaac caccagagga
     2401 atttgcaagt cctcgatgtt cttggtccgc aagtgtcgcc tcaagaaata acgaaagcgc
     2461 ttactatcga acaaacccgc cttaggaatc tgcaactggg cgaattccga gaactcacgt
     2521 ccggtaaaaa gctcttggat ctccgccgcc gaataaccat cggcaaacaa agcgcccatt
     2581 aaagctcccg cgctggtacc gactataata tccggtctta gcgcacattc ttccatcatt
     2641 cgaaatacgc cgatatgcgc aaaacctttc gctccgcctc cgctaagcgc caagcccaac
     2701 ctatagggtt tatggtttgt ctcttctgcc atttatttct tgtctcttaa tctggtaaca
     2761 aatatgctgt tttttttaat tagaaacatt attattaggg aaaaagtttc catcctcttt
     2821 tatttttgct acatttacac ggaaagcaaa ggtgttgtca cattgttttc ttaagtataa
     2881 cattaaatct accatgttat gattacgagt atcttctgga ttatcccgtt agcgtctgtc
     2941 ctagcgctag cattcgcctg gttcttcttc aggcaaatga tgaaagagag tgaaggaact
     3001 gagttgatga aaaagatcgc ctcctttgta cgtgaagggg cgatgtcgta tctgaaacag
     3061 caatacaaag tagtcgcctc ggttttcgtt gtcctagtaa tcttattctc tattatggcc
     3121 tatggcttcc atgttcaaaa cgaatgggtt ccgatcgcct tcctgacagg aggtttcttt
     3181 tcaggattag cgggtttctt aggcatgaaa acagcgactt atgcctcggc ccgtacagcg
     3241 aacgcagccc gcacttcctt gaataaaggt ttacaagtgg ctttccgaag cggggcggtc
     3301 atgggcttag tagtcgttgg gcttggattg ctggatatct cattctggta tatcctgtta
     3361 aatgctttca tcccagacga ggctttggac ccgacccata aactcaccat tatcacgaca
     3421 accatgctta cattcggaat gggtgcctcc acgcaagcct tgttcgcacg tgtgggagga
     3481 ggaatctata cgaaagccgc cgatgtcgga gcggatttag taggtaaagt tgaggctggg
     3541 atcccggagg acgatcctcg taacccggcg acaatcgccg ataacgtagg cgacaatgta
     3601 ggtgacgtcg ccggtatggg agccgaccta tatgaatctt attgcggttc catcctagcg
     3661 accgccgcat tgggagccgc cgcattcgtt tcttccggaa gcgtagaatt acaatataag
     3721 gcggttgtcg ccccaatgct tatcgccgct gtcggtatca ttttatctat tattggtatt
     3781 ttcgccgtcc gtacgaatga gaacgcgacg atcaagcaac tactgaaagc cttagccata
     3841 ggaacgaact tgagttccgt attgatcgct atctccacgt tcgggattct ttatgtatta
     3901 ggcatggaga attggttctg gatcggttgt tccgtgatcg taggtctgct agtcggaatc
     3961 gtgatcgggc aagcgacgga gtattatacc tcccagtcct ataagccgac ccggctggtt
     4021 tccgaatcgg ggctgacagg cccggcaacg gttattatct ccggtctcgg actagggatg
     4081 ctctctacgg ccatcccggt acttgccgtc gtggtcggta ttatttgttc cttcttgttc
     4141 gcctccggat tcgacttcac gaacgtgggc atgggattat acggaatcgg tatagctgcc
     4201 gtaggtatgc tatcgacctt aggtattacg ttggctacag acgcttacgg tcccatagcg
     4261 gataatgccg gaggcaacgc cgagatgtgt aacctaggga aagaagtccg caagcgtaca
     4321 gacgcattgg attcattagg aaatacgact gccgctacag gtaaaggttt cgctatcggt
     4381 tccgctgcgt taaccggctt ggctctgttg gcctcttatg tagaagagat caagatcggt
     4441 ttgctccgtt taggagagaa cgtcctgaat tttaccgatg gcaggagtat cgaaatatct
     4501 aaagcctcat tctcggactt tatggtatat tatgatgtta ccttaatgaa tcctaaggtt
     4561 ttagccggaa tgttcctagg ttccatgatg gcattcatgt tctgtggcct tacgatgaat
     4621 gctgtagggc gtgcggccgg gcacatggtg gaggaagttc gccgtcagtt caaggaaatc
     4681 aagggtattc tgactggaga ggcacaaccg gattatgccc gttgcgttga gatctcgacg
     4741 aaaggagcgc aacacgaaat ggtacttccc tccgttttag ctattatcgc ccccatctta
     4801 accggactca tatttggtgt gacgggtgtt gtcggattat tgatcggtgg attaagcacg
     4861 ggcttcgtat tagccgtatt catggcgaat gccggaggag catgggataa cgcgaagaaa
     4921 ttcatcgagg aaggaaacca cggcggcaag ggtagcgagg cgcataaggc aaccgttgtc
     4981 ggcgatacgg ttggcgatcc gttcaaagac acttccggcc cgagtttgaa tatccttatc
     5041 aagctgatga gcatggtagc gatcgtgatg gcgggattga cggtggcttg gagtttgttt
     5101 taatagttga ccgttagtag ttggcaattg acagttagag aagtaaattg acaaattaat
     5161 agagaaaact aaataattgt caattgccaa ctgtcaattg tcaactgttt tgtatttttg
     5221 cgtcgtaaaa acataaaaca attcaacaat gtcaatctca cgctttaatg ctgtggagaa
     5281 ggcatccaac cgaaaggccg tggaagccgt tactcccgaa cacaaagtat ctgagtacta
     5341 tggcgagaat gtcttcaacc ggaaggcgat gcaaaaatat ctctccaagg aaacgtacaa
     5401 agccttgacc cacgccattg acaatggcac acctatcgac cgggaaatcg ccaatcatgt
     5461 ggcagccggc atgcgtatgt gggcactgga aaaaggagtc actcattata cccactggtt
     5521 tcaaccgctt accgatggta ccgccgagaa gcacgacgct ttcgtggaac acgatggtaa
     5581 cggtggcatg atcgaggagt tcagcggcaa attgcttgtc cagcaagaac cggacgcttc
     5641 cagtttcccg aacggtggac ttcgtaatac cttcgaggcc cgcggctact ccgcttggga
     5701 cccttcctct cccgctttta tcgtagatga cacactttgt atcccaaccg tatttatcgc
     5761 ttataccggt gaagcgctgg attataagac cccgctgatc cgctctatcg aagtattggg
     5821 agaagccgcc aaagacgtat atcggtattt cgatgaggat gtcaataaga taattactta
     5881 ccttggttgg gaacaggaat atttccttgt tgacgaggac ttgtattccg ctcgtccgga
     5941 tctctcactg accgagcgta ccttgctagg acatgagagc gcaaagaacc aacaattaga
     6001 cgaccattat tttggcgcta tcccctctcg tgtacaagaa ttcatgaaag acttggaaac
     6061 cgaatgctat aaactaggta tcccggtaaa gacccgccat aacgaagtag cccccaacca
     6121 gttcgagcta gctcctattt acgaggaatg taacctagcc aacgaccata accaattatt
     6181 gatgtcggtc atgaaacgtg tctcccgccg tcataatttc cgtgtattat tgcacgagaa
     6241 gccatttaac ggggtaaacg gttccggtaa acactgtaac tggtctatgg gaacggacaa
     6301 gggggtaaac ttattctctc cgggtaaaga ccgtgaggac aacctgcgct tcatcacctt
     6361 cgtggtgaac actatcatgg ccgtttataa atacaacgct ttattaaaag cgagtatcgc
     6421 ttccgccacg aacgcacacc gcctaggcgc gaacgaggca cctcccgcta tcatctccac
     6481 tttcctcgga acgcaaatca gtgagatctt ggataagttc gagaatagct ctatcgagga
     6541 cgctatcgag gtagacgata aaaagggctt gcatcttggc ttcgggcaga tccccgaact
     6601 gctgttggac aatacggatc gtaaccgtac ctctcctttc gctttcaccg gaaaccgttt
     6661 tgagttccgt gccccgggtt cttccgtgaa ctgcggatca gccatgttag cgttgaactc
     6721 cgccgtagcc tatcaattgc aacaattcaa gaaggacgta gaggctttgc aagcggaagg
     6781 aaaaagcaag gaagtagcga tcttcaaggt gctgaaagcc tatatcaagg aatctaagcc
     6841 gatccgcttc gatggaaacg gttattcgga cgaatggaaa gaggaagccg ccaagcgagg
     6901 tctggattgc caaaatagtg ttccattgca atatgacgct tatcttaaac cggagtcgat
     6961 cgagatgttc acgtctaccg gcgtacttac ccagaaagaa ttggaagcgc gtaatgaggt
     7021 aaaatgggaa gtctatatca aaaaggtaca gatcgaggct cgggtattag gggatttatc
     7081 cttgaaccat atcatcccgg tagccgttcg ctaccagagc gtattgctgg ataatatagc
     7141 gaagttgaaa gagacattcg gcgatgaccc ggaattccgc gatatgtcgg aagagccccg
     7201 tcgcttggtt cgtaagatag ccgggcatat ctgtgccgtg accaagaaag tggatgagat
     7261 ggtagaggcc cgcaagaaag cgaaccgctt gaccgatatg cgggaaaagg cgatcgctta
     7321 ccacgactcg gtagcccctt atttggatga gatccgtgac catatcgatg atctggaact
     7381 gatggtggac aaccagatgt ggccgttgcc gaagtatagg gaactcctgt ttatccgata
     7441 aaaaacaccc gtactggcgt tgccttgcgc cagtatcggc atagcctcac actgatatag
     7501 gcgcagcctt ataccgatac tggcataagg ctacgcctat actcccgttt accacttcac
     7561 ataagaagca ttcatcaaga agtcataatc atgtttcatc gcttgcagcg gtgtcatatt
     7621 ataacgctct tgctcaatga agtaatcctc taatccggct ttctccgcca cagcgaataa
     7681 ggatttgaag tctacgattc cggcgcccat ctctgtgctg ccctttccat ccgcattcgc
     7741 gtctttcaag tgccagttgg cgaaacgacc gggataacgg ttcacgtaat catgacattt
     7801 aaaaccgcca tacactaatt gagccgtatc gatctggaaa gtaaccagcc ctttgtccgt
     7861 attctcgatc atcacgtcga acgggatctt cccttccagc tcatggaatt catccacatg
     7921 gttatggaaa gcgaaacgca acccattcgc cttcgcaatc tcaccacatt tattaaattg
     7981 atccgctaaa cgcttcacgt ccgaaaggct cttgatatct ttggagggat aacccgcctg
     8041 aacaatccat ttacagccta cctctgccgt atcggcggca ttctttttcc agaagtccca
     8101 tcccttggta tcaccctccg ccagcaaacc gcttccggta tgggaaccta ccatacgggc
     8161 acccagatcc gccagatatt tcttcatctc ggccggggat ttcccgtaga atttgccatc
     8221 ccggtaaccg gcggcttcca tccgtttata accgatatcc accaaagcct tcatcgtacc
     8281 gtcaaaatcc gtcttcaagt cgtcccggac actatacaac tgtacaccta tcgctttctc
     8341 tttcttagcc aagatagagg caaagccgtt cggtactaca ctcagcgcag ccacagcggc
     8401 acccgctttc aaaaaattcc gtctcgttat catcatacta ttctttaaga ttaacgtcgc
     8461 taaaggtagc aaaattattt ctactttcgc gcacatttaa acaaacgatc atgcaaggaa
     8521 caaaaaatct gaccgaaggg gtcatctccc ggcaactatt caatctggcg atgccgatca
     8581 tgggtacctc atttatccaa atggcctata gcatcaccga catggcttgg gtaggccgat
     8641 tgggaagcga ggccgtagcc gctatcggcg ccgttggtat ccttacttgg atgacgaact
     8701 cgatctctta cttgaataaa gtaggctcgg aggtgagtgt cgggcaaagt atcggggcgc
     8761 aaaacgtgga agatgcccga ggattcgctt cccataacct aacgatcgcc ttgatcctct
     8821 cgctttgttg gggattcttg ctattcgtcc tcgctcatcc gattatcggc ttctacaaac
     8881 tggaggaacc gatcacgttg aacgccgtgg aatatttgag aatcgtcgct tccgcattcc
     8941 catttatctt cctctcggcg gcgtttaccg ggattcataa tgcggcggga ttgagtaaga
     9001 ttccatttta tatcagcgga acaggtcttt tactgaatat ggtgctagat cctttattta
     9061 tactcggctt ccatttgggc acggcgggcg cagcttgggc tacgtggatc tcccaagcgg
     9121 tggtttgcgg actattcgtc tatcagctaa aatgccgcaa taaattgttc gggggattcc
     9181 ctttctttgt ccgtttaaag gaacgctaca ccaagcggat cttccaattg ggcctgccgg
     9241 tagcgttatt aaatacattc ttcgcgatca tcaatctttt tatggctcgt acagcttcca
     9301 cctacggagg gcatatcggt ttgatgacgc ttacggcagg cggacaaatg gaggcgatcg
     9361 catggaacac ctcacaaggc ttcagtacgg ccctctccgc tttcaccgcc cagaactacg
     9421 ccgcacgcaa gaaagaacgt atcttgaccg cttatcatac gacgcttaaa atgacttcta
     9481 tcatcggtgt actctgcacg ttgttattcg tcttttacgg tagcgaggtc ttctcgctga
     9541 tcgtgccgga gcaagccgct tatgaggccg gtggtatatt tctccggatc gacggatatt
     9601 cgatgatctt catgatgctg gagattacca cgcaaggcat gttctacggt accggccgaa
     9661 cggttccgcc ggcgatcatc agcatctcgt gtaacacctt acgcatacct ttggccatcg
     9721 ggctagcggc agcgggactg ggtattacgg gtgtttggtg ggcgatcagc ctttccagca
     9781 tgctaaaagg tgtcgtcgct ttcatttggt tcagtatctt acagaagaag atcttgtaag
     9841 cggaacaatt cttaccgatt ttccgtacat tcgcgattaa aatgacattc aattaaaaaa
     9901 acaacctata tggataacaa attcaaaccg gaaaccctgt gcgtacaggc cggttggcaa
     9961 cccaagaaag gagaacctcg tgtcctcccg atctatcaaa gcacgacatt caagtatgag
    10021 acgagcgagc agatggctaa attgttcgat ttggaggaaa gcggctattt ctatacccgc
    10081 cttcaaaacc cgacaaacga ggctgtagcc gccaagatcg cggcgttgga aggtggcgtg
    10141 gccgccatgc tgacctcatc cggacaggcc gctagctttt tcgctttctt caatatttgc
    10201 gaggctggcg atcatatcgt aagcgctacc agcatttatg gaggtactta taatctactg
    10261 gccgttacct tgaagaagct gggaatcgaa tgcacgttcg tagatcaaga tgcgagcgag
    10321 gaagagatct ccaaggcttt ccgcccgaat acgaaggcga tgttcggcga gatgatctcc
    10381 aatccgggcg ttatggtatt ggatgtggag aagtttgccc gcatcgccca taatcatggc
    10441 gtacccttga tcgtcgataa tacgttcgcc acgccgatca attgccgtcc gttcgaatgg
    10501 ggagcggata tcgttacgca ctccacgact aaatatatgg atggccatgc cacgagcgtg
    10561 ggtggttgta tcgtggacag cggcaatttc gattgggaag cgcatgccga gaagttcccg
    10621 ggactttgcc aaccggaccc ttcttaccac ggattgacct ataccaaggc attcgggaaa
    10681 ttagcgttca tcacgaaagc gactagccaa ctgatgcgtg acctcggagc gatccaatcc
    10741 ccgcaaaacg cattcctatt gaatctggga ttggagacct tgcatcttcg tgtaccgcag
    10801 cattgcaaaa acgccttggc ggtagcgcag tggctacaga aatgtgataa ggtagcttgg
    10861 gttcattatc cggaattgga aggcaacccg taccatgaac tcgccaagaa gtatctaccg
    10921 aatggctctt gcggtgtatt atccttcgga ttgaaaggtg gacgtgaggt agcgatcaag
    10981 tttatggata gcttgaaact cgccgctatc gtaactcacg tagcggatgc ccgtacttgc
    11041 gtgcttcacc cggccagtca tacgcaccgc cagttgagcg atgagcaatt gatagaggct
    11101 ggcgtggctc cggacttaat ccgcttctct gtaggtatcg agaacgccga tgatatcatc
    11161 gccgatattg agcaagcgct caataaataa gacatctatg ccatgctgat gaaacgcttg
    11221 tgccatcagt gtggcacgcc tgtgccatca gcatggcaca cctgcatcta cagcacggta
    11281 ctgctataag ttcctagata ggcaggaatc tccccagacg cgccacccaa tttgtcgtaa
    11341 tcctccctag gctcgttacc ggatgttcct cacgcaacaa atcctcacgg aactcacgaa
    11401 gaataagcca atccgcctgt ttcacccaat gccggaagac cgaattctcc acatgacttt
    11461 ccgaaatgga taataacacg tccagatcaa aacaatcagc gacaacgcct gcgccagaca
    11521 aagaggcatc gtaagcattg caagcttgct caatatgtgt aggaaccatc aatacaggtt
    11581 tattcagata catcgcctca catacggatt cgaacccggc ggtcgtagca taagccttcg
    11641 cccccgacat ataacgtaga aacaacgtat catccagctg atggaaagaa aggcaatcat
    11701 ctattttcac ctcggctcgc tgatctttct tatcccaaaa gaaatgcatc ggaaccgaag
    11761 gatgacggga atgccaagaa cggatctcct cactaaaccc gctattcaac aaataaccat
    11821 gcaaataact gccgttcgag ggaaccgcat ccaagacttc ttgccttaat aaaggaggaa
    11881 ccacgactat tcctcccaac ggcgcctcac gcatcttccg aaaagacaag gctaattttt
    11941 tgacggagcc tatcgccgtt aatctcgtaa aaaaccgtag cgacgccaac gacaatgtgc
    12001 tctgcttcgg gaaaacgaag tccggatgca agaatagata ttgatgggcg atacatacca
    12061 tcgttgcttt cggacggaga atcaagtaag tcagccccgt caatagctcg tagaagttca
    12121 cgacaacatc cgcatccgtc tgccgaatca tccggtcgat ataacggata cttcccatgt
    12181 atttatgcag acgcaataca ttatataata cgctacgcat caaactcact tgtttattct
    12241 tagccgtcgg taaaaaattc ggactttcaa acggatatac cggcgacaga atcttattca
    12301 agaagaaatc cggtaaacgg cgggccggac tttttccgac caacacacca acgatctcat
    12361 gtccttcggc catcaatttc tggcgtaagg ataacgcttg ggtcaagtgc ccacgtccct
    12421 caccttgtat gataaacagg attttcatac ggcatccgca tatagttgta cattattata
    12481 tgtaacaata tcccactctc cttgttcatc ctccacgaga gcggtcatgc tttccaccca
    12541 atcgccggaa tttagataat gcacattacc ataccatacg ctcgccgctt ggtgaatatg
    12601 gccgcaaata atcccgtcca aatgcttggc ctccgctaag cgtaccaact ctttctcaaa
    12661 ctccgagata taagagaccg cacttttcac ccggtgtttc acctcttggg ataaagagaa
    12721 ataaggtttt ccttgccgct ctctacgatg attgtaaacc ttattcaacc acaataaaaa
    12781 agtatatccc acatccccga gcatggcaag ccaacgcata tgggtcgtaa ccgtatcgaa
    12841 aatatcgcca tgtgtcacga aatagcgttt tccttgtctc gtcttcagta aataatcctt
    12901 tacgatcgat atattggaga acttaaaagg agccaagcta tcgagaaaat catcatggtt
    12961 ccccactaca tagataatct ccgtacccct tttctccatc atcttcatca ataccttaaa
    13021 gaaatcggta tgcttttgtt tccagcgttt accggatttc ttcaattgcc agccatcgat
    13081 gatatcacca ttcaaaatca atcgatcgca atctacgtgc ttgagaaaac gggtgacctc
    13141 ctccgtccgg gaatgttccg atcccaaatg gatgtcagag aggacaatag tcggatagta
    13201 ctttcttaat atcatctttt ccttgtttaa gatgatacaa aagaacactt tcggtattac
    13261 aagttcacga caacctaatg aaaaagacat aacaaaaagg ccagctcttc acaaagccgg
    13321 ccttttctcg tttaacttta aatattaaaa aattatgatg acattttact ttacctattc
    13381 ttctgattga gtagcctcgt aagcctttaa caacttctct tgtacatcgg caggaactaa
    13441 ctcgtaacta gcgaacttca tcgtaaagga agcacgtccg cccgtaatgg agcttagtga
    13501 agtagaatag ttagacatct ctttcaaagg aactttcgcc aatagtttct caaatccctt
    13561 ctcgctattc atacccataa tcaaggcacg gcgtccttgc aagtcactca tcacatctcc
    13621 cagataatca gcaggaacgg aaacctcgac atcgtaaaca ggctccaaga tcttagggcc
    13681 agcctccttg aaagcggtac tgaacgcatt gcgtccggca agcatgaaag agatttcatt
    13741 actgtctacc gggtgcatct taccatcgta tacgcaaata cgcacatcgc gagcatacga
    13801 acccgtcaac ggcccttgct ccatacgagc catgatacct tttaggatag ccggcaagaa
    13861 acgagcgtcg atagcaccac caacgataca gtttacgaac acgactttac caccccaatc
    13921 caaatcaatt atttgagtat cacgaacatt catcttatac tcctgtccgc cgaaacggta
    13981 ggtatccgga gcaggcatac cttcataata aggctcgata atcaagtgaa cttcaccgaa
    14041 ctggcctgcg ccaccagatt gtttcttatg gcggtaatcc gcacgggccg ctttcgtaat
    14101 cgtctcacga tacgggatct tcggctccag atattcgatc ggcaatttat cattattctc
    14161 gattctccat ttcaatgtac gaagatggaa ctcaccttga ccggaaacga ttgtctgctt
    14221 caattccttg gactgctcga ttacccatgt cgggtcttcc tcgcgcatac gtatcaagat
    14281 ttccatcatc ttctcggcgt cagcctcatt caccggcttg atagcacgac gatatttcgg
    14341 atccggatat ttaatgaagt cgaaacgata atcacaaccc tttccgttca atgtattacc
    14401 acggcgaaca tcctttaact taacggtcgc tccaatatca cccgccacca tttccgtaac
    14461 cggggtacga gtttgtccgg ctaccgcaaa taactgtgcg atacgctcct tggaaccacg
    14521 atcggcattc atcaaatcgt caccttcttt tacttttcct gatatcactt taaaatagga
    14581 aacctgacca atatgaggtt ccacggtagt cttgaagaag aacaagctag taggaccatt
    14641 cgagtccgga gtcacctcta cgccttccgt agtaatcaga cgaggcatct tgtcggtaca
    14701 aggaaccacg ttacccaaga actccaacgt acgacgaaca cacatatcac gaccggcaca
    14761 tacgcagaat accgggaaca taccgcgagt aaccaagccc gcacggatac cggcacgcat
    14821 atcatcctcg ctcaaggcac cttcctcaaa gaatttctcc atcaaagtat catcgttctc
    14881 agcggcggct tccaccaagg cttgatgcaa ctccatcgcc ttatccattt cctcggcggg
    14941 gatttccaat acatcaggaa ctccaccttc cggtttccaa cgatacatct tcatttttaa
    15001 tacatccacc acggcattga aagaagagcc gcagctaatc ggatattgga tcggaacgat
    15061 cttactgccc caacggtctt tcaactgggc gatggttccc tcatagtcgg ctttatcatt
    15121 atcaagctga ttgacaacaa aaatcaccgg tttatgaaat tgttcagtat accggaactg
    15181 gttaatggtt ccaacctcaa caccgtactg ggcattcaat accatcagtg ccgtatccgt
    15241 gacattcaga gcggaaacag ctcctccaac gaaatcatca gaacccggac aatcgatgaa
    15301 attcagcttc cgatcctgcc actcaacact gaaaacggtt gagaaaactg agtatccata
    15361 ctctttctca accgggaaat aatcggacac cgtatttcct gcctcaacgg agccgcggcg
    15421 ttttataact ccaccctcgt aaagcatagc ttcagcgaga gtggttttcc cagagcccga
    15481 acttcccaag atagagatgt tcttaatttc atttgtttgg tatactttca tgatatcagg
    15541 atttatttga gtttaacaat acgtttattt ggcgtgaatc actttcacga gggcgcaaat
    15601 tagagattgt aaaggaaaaa agcaattatc gcccggtgtt tgagaactat gttgtgcagc
    15661 agcaaggttt tttgaaattt aaattatatc tttgtgtaaa gatataattg tgtccataca
    15721 gatggcaggt ttatacatcc acgttccttt ttgcgccaag cggtgtttat actgtgactt
    15781 tttttccaat acggagatga agtataaaga gccgtatata aacgcactta taaaagagat
    15841 ggaattgcgg aagggatata taggaaacga agcattagaa accatttact tcgggggagg
    15901 caccccctct caattagacg agaaggattt tggcaagata ttcgaggcta tctatcgtca
    15961 ttttgatgta gccgagcaaa tggagattac cttagaggcg aatccggatg acatgaaacg
    16021 agaatatgta tcgcttctcc gtaattatcc ttttaaccgg gtcagtatgg gtgtacagag
    16081 ttttcatccg gaagatttgc gttttctgaa tcgtcgccat gaccggcaac aagcgattaa
    16141 agcagtagaa ctatgcaagg aatatgggat tacaaatatc agtatcgatt tgatctacgg
    16201 actccccaac caaacgcagc aagcatggga agagaatttg cgacaagcga tccggttgga
    16261 tgttccccat ctttccgcct accacctcat ttacgaggaa ggtaccgcac tttacaaatt
    16321 gctggaagcg ggaaaagtga cccccataaa cgaggagtta agcgtctcgt tcttttccac
    16381 attaatagat cggttggcag aagcaggcta tttgcattac gagatatcta atttcacccg
    16441 tcccgggttc ttctccaagc acaatagctc ctactggacc ggaaagaaat atctggggct
    16501 cggtccttcc gcccattctt ataacggaat agaccgggaa tggaatccat cttctctacc
    16561 tatatatata gacggtatag aaaatgggca tccgacaata gaatccgagg atttagacct
    16621 atgcacccgg tacaacgact tcatcatcac cggccttcga accatgtggg gagtctcttt
    16681 cgctgatatc cagacaaaat ttggcaggaa gctcctttct tattgtcaaa agcaagctca
    16741 accccatatc aaccaaggtc tcttattaca aaccgatgac aaattgattt tatccaagtc
    16801 aggaatcttc gtttccgacg gaatcatgag tgatctactt tgggtataaa aattaacaaa
    16861 accaccactt tcgccaacaa acctgttagt taaaagtaca tttcctgcac attttcacga
    16921 tttttgagaa ataaaacgac gcatattaaa aaactattac atatatttgc agcatcaaaa
    16981 acagcaaaca gtgccatatt tgtatataat atcaggttgc aacggagcag gaaaaacaac
    17041 agcttccttc acgattttac cagaaatgct aaaatgtagg gagtttgtta actcagacga
    17101 gatagccaag ggactttccc cttttaatgc agacagtata gccgtcgccg ttgaagctag
    17161 tcgtattatg tataagcgga taaaggaact catcggtgct ggtgagactt tcgcaatgga
    17221 aactacgctg gccacccgtt cagtcgcaaa cctgatacgg gaagcacaaa gggaaggtta
    17281 ttatgttaca ttgctttact tctggctgaa tacgccggat ctagccgtgg aacgtgtaaa
    17341 aatgagggta gccgccggag gtcacaatat tccggaagca acgatacggc gtcggtatga
    17401 ggccggtatc cacaatttat ttgagctata ccttcctatt agtgactatt ggatgataac
    17461 tgataattcg atgtctccca tggaagtgat cgccaaggga ttcaagaatg ataaaaggga
    17521 agtgtataat ctagatattt ttacaaaact tgaacatcat gaatgagcaa gaagttagag
    17581 aattcgaaga gaatatagta aaaggtgcaa atatagcttt tcagcgtttg gtgaatcaga
    17641 agaagaagga agacggagag ttggtattct ctcgtaacgg tcatatcttc agagtcaaag
    17701 ctgttgatct tgacaagatt tattaagtta tagatataca tatacaaaaa gaggagacgt
    17761 atctttcagg gatatgtctc ctctttttgg ctttatagaa aaaggaactt aggttcatgg
    17821 gcgaagtatg ttaacatact tcggcatttc agttaacata cttcgcccac gaagttaact
    17881 tacttctcta tcttgagaat tccatctcgt tcaataaata accggctccg gcatatttat
    17941 cgattacgaa taggacataa cggatatcta cgataatact gcgttgataa tcgggcagat
    18001 attggatatc ccctcctact ccttcccagt tacggtcgaa attgataccg attaactctc
    18061 cttgtccatt caataccgga ctaccggagt tccctcccgt tgtatgggtc gtagcacaga
    18121 aggcaaccgg cattttaccg ttaggcatct tataagggcc aaagtctcct gcttgatata
    18181 attccttcaa acgagcagaa accacaaatt cccaattcgt agaatcctcc ttctccatga
    18241 cgccgtctaa agtggtttga tgaccataat aatcgcaatc acgaggactg taacctttca
    18301 cctgcccata agtcagacga agcgtagagt tcgcgtccgg aaaactagcc aagtctccat
    18361 acatcgctaa aagtcctttc acatacgcac gatgggcgat cgcatatccg gcatcaaaat
    18421 cagccaaagc cttatctaac gcctttttct catcctttac ggattgcgcg aacagaatca
    18481 tcggatcttc tctcaaagtt ttgacagacg ggtgctcctt gaacgcatta aagttcttct
    18541 cgctaccata gatcgattta tcaaacagat aatctacgaa tttatccaca tcccccttaa
    18601 acttgctatc gattacggaa aaataagccg gctgcgactt cggagcgacc aaacgcctat
    18661 attcctttaa catgactttc gctatcttct tatcaaccat cggcgcataa tccttatcag
    18721 caaaacggtg gaaagccctc tccaattgag tgacctgttt ttgctgctcg gaacgatctt
    18781 tcccctccaa agcctcacaa acagtctcga tatcggtcgg aactttggag aactcgatgc
    18841 cacggctcaa tgcctcatcc aacatccaac tacggaaacg caaatcctta cgatcattaa
    18901 cgatctgctc caatgtcaga agcgcttccg gataagcagg ctcacacatc ttcttcgacc
    18961 aagcgatcaa acgatcctgc tcatcgtttt tcacctgctc aaaattacgt ttgttgatcg
    19021 cccagttact accgatcgca ttcttataag cgttcgtaga acctgcatac ttactagcgt
    19081 attgaatccg aacttgcgga tctttcaaca tttcttccag catcgcctct tgacggagat
    19141 tacggatatt aatacgtacc gcattatcta tatcccgacg ttcagctacc tcccatgagg
    19201 tatagtattt attggtacgg ccggggaacc ccatgatcat ggcataatcg ttctcctcca
    19261 caccttttaa agaaagcttt agccaacgtt tcggacgaag cgggacattg gtttccgaat
    19321 aaggtgccgg atttccgttc gcgtcggcat acacacggaa aagagagaag tctccggtat
    19381 ggcgaggcca catccagtta tccgtatccg ccccgaactt accgatagag gaagggggag
    19441 caccgactaa acggacatcc gaatagatct tcttggtaaa catatagtac ttattacctc
    19501 cataaaaagc cttgatctcg acttccgtac cggggttatc ctgtaagaac ttctcaccta
    19561 ctttcgcttt agcgaggcca ttcaagtact tagcggacaa gaattccatg ctgttcggat
    19621 ccgtgatctt tttcagttcc gtcctcacat aatccgtcac gtcgtcgatc ttatcgataa
    19681 aagtaaccgt caatcccgga ttcggaagct ccttatcacg agacatcgcc caaaagccgt
    19741 ccgtcagata atcatgttcc aaggtactat gccgttggat gctactataa ccacaatgat
    19801 gattcgtcag caccaacccg tccggagaga tcatctcgcc cgtacaacca ccgccaaaac
    19861 gaaccacggc gtctttcaag gaaggagcct cggcgctata cacttcctga tcgcttaatc
    19921 gcagaccaag ggcctgcatc tccgcaaact tttgttgctt caataaaggg agcagccaca
    19981 tgccctcatc ggccaagacc ggaaacgcca atatagcggc cgctacagat aaaaagagtt
    20041 tcttcatgta tttgaactat taaaaggatg ttttgtcaac attgaattat aataacggcg
    20101 atctccactt acctccttac caagccaagc cggtttctca aaaggctcgt cctcagacga
    20161 taactcgatc tccgcaagga tcaacccttc attcgctccg tggaaaacat cgacttccca
    20221 cgtatggctg cctctgggaa ccagataacg aaccttgtcg atcgcacccg gctcgcaaag
    20281 ttccaacaac cgctcggcat ccaccagagg aatcttttgt tcgaactcat aacggctcaa
    20341 gcctttctca tccgaagcgc ctttgatcgt taggaatccc tcctctcccc ggatacgaat
    20401 acgaaccgta cgtccgggct gtgagcaaat atatccctgc acgatacggg tggagctaac
    20461 agcctccggt aagaaatcac cggagaccaa gaatttccgt tctatctcaa tggccatgtt
    20521 tcgaggtatc agccttaatc gttaccatcg tcgcaccaaa gccatattcg cggaaagaag
    20581 cgtcttgaaa ataatgttgc ttataatggg tcttcaaatc cttctcgatc gccttacgca
    20641 gtacaccatc gccttttcca tggataaaga caatcttctg tccgttatta agagcgtact
    20701 gatccatcac ctcacggaat tttcccaact ggtacgtcag catatccgca ttgctcaatc
    20761 cattcgtatt atccaacaat tcggttatat gcaaatcgat ctcaaggata gcgctattcg
    20821 tcggcttctt tttcacgatt tgccggggaa ccctacgttc ctcacgaacc ttttgctgca
    20881 tagcttcctt caactccgcc gcagagacca atagttctct ctcgggcaag tcattgcgga
    20941 taatcggata aatcaaggca tcctcctcaa agaaatcatt ctccataaag cagtgaagct
    21001 tgtagaactt aaccgtatcc aagcgcaact ctacagatac ggcgtttttc aacgaatagg
    21061 gtttatcctt cttgaaagcg atcagttgca cgcagatcct ttccagatca ttcaactccg
    21121 gcttaccgaa ctcctctagg aatattttcg tattcggctc aataatcccg ttataacgac
    21181 ttgtccagct attattcgtt cggttcatat aattgaagaa caaatagtaa ttgctatcat
    21241 tcacgaaata cgtctcatag ccacattgct gaaacgcctt cggatcgacc gggagataag
    21301 ccagatacac attcagacgc tctccctccg gtgtctcctc gaccttttcc tctttgggtt
    21361 caggcttctt tggggaagga gtctctaccg gagcctgtac tttcgggcga ttcgagctat
    21421 gcacttgcat atcattgccc ccaaccacga cacattcctt gatcaaggca ggaacctcaa
    21481 acccatcctc atcctcaacc aacacttggt cctttccacg gaatccacgt acgactccac
    21541 ctcccacact attcaggaag cgaactttat cacctatttg aatactcata ttctatacct
    21601 tattatatta tgcgcacaaa attagggaat aatccgcgaa tccgaaacct atttactact
    21661 tttgcactcg gaatccgtac aaacggatgt ttttttaaca ggacagaaga agtaatgaag
    21721 acacaagaaa tacgtatcga agattataac tattcgttac cggacgaacg aatcgcgaag
    21781 tttccattgc ctaaaaggga tgagtccaaa cttttactct accgtaacgg ggaaataagc
    21841 gaaagtatct ttaagcatat cacggattat cttccccaaa acagcttgat ggtattcaat
    21901 aatacccggg tcatacaagc ccgcctactt ttccagaaag agaccggcgc acgcatcgag
    21961 attttctgct tagagcccat cgagcctcat gattacgcct tgatttttca agagacccga
    22021 cgctgtagct ggacttgctt ggttggcaac cttaagaaat ggaaagaagg cactttatcc
    22081 aaaacgatct tcattaagga tcaaccggtc gtgctgacag cggataagaa aaagtctcat
    22141 ggtgacacac atttgatcga attcacatgg gataacgaga cttatacatt cgccgatatc
    22201 ttggatgccg ccggggtctt gccgattcct ccttatttac acagagaaac agagaagagc
    22261 gacctacaga cctatcaaac ggtttattct aagataaaag gctccgtcgc cgcaccgacc
    22321 gccggacttc atttcacttc ggaagtactt gccgatatag atgctcgggg catcgggcgg
    22381 gaagaagtca ccttgcatgt cggagcgggt acctttaaac cggtaaaaag cgacacgatc
    22441 gaagggcacg agatgcacac ggaatttatc tccgtccgcc gcagttccat cgaacgtatc
    22501 aaaagcaacc ttggaaatat catcgccgta ggaacgactt ccgtacggac cttggaaagt
    22561 ctctattaca tgggcgtgat cctagataat aaccccgaag cgacttccga agatctcgtc
    22621 gtaaaacaat ggatgcctta cgacatgaat aacaaccggc tgacagcgga gcgttccctt
    22681 caaaacatcc tcgattatct ggataagcat gatgcggata cgctggtaac ggctacacaa
    22741 atcatcatcg ccccgggcta tgagttcaag atcgtaaaag gaatcgtcac caacttccac
    22801 cagcccaaaa gcaccttgct cttgctgatc tccgctttcg taaaaggaaa ctggaaatcc
    22861 atctatgagt atgccttaga gcacgatttc aggtttctnn nnnnnnnnnn nnnnnnnnnn
    22921 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    22981 nnnnnnnnnn nnnnnnnnca ttttactata tatgttttat ttttgcttat cgtatcttcc
    23041 ttgtattcct gcaaatcggc gaagttgagc gatgccgagg agaagcagcg tatcggggaa
    23101 tactatgagg cagccgccat ttatcgtaaa gtttacacga aaacatcccc gaagaaaagg
    23161 gatttgcgcg gctatatcgc ttaccgtatg gccgaatgta accggttgat caataatacg
    23221 gcgaaagcga ctagtgccta tatgaacgcc atccgctatg attaccccga tagtaccgtc
    23281 tacctacgca tgggacagat gttacagaag accggacgtt atccggaagc gatcaagaac
    23341 tacgatatct atatggagaa cgatcctagc aatttattag ccatcaacgg catacaagga
    23401 tgcgagctgg ctcccggatg gaaaaagaac cctacccgct acgaggtaag gcgcatggac
    23461 aaattcaatt ctcgccgagg agaattcagt ccgatgctgg ccggagataa atacgaccaa
    23521 ctatacttcg cctcctcccg ctcgaaagac aaggacgcga aagtcagcgc catcaccggg
    23581 caaaataaca ataacctctt ccttgtcaag caagacgaga aaggggcttg gctggctccc
    23641 gtagagctcg aagacgaggt gaatacggaa tacgacgaag gaaccccctc tttctccccc
    23701 gatggaaaca cgatgtatta tacctattgc gcccaagatc cggaaggccc tcgtaccgcc
    23761 gagatttaca tatctacccg aagcagcgcc aaatggggaa aaggaacccg tgcgacaatc
    23821 gtaaaagact cggttaccgc cctcggccat ccctccatct cgccggacgg caaatacttg
    23881 tattttgtat ccgacgccgt aggcggtttc ggcggcaagg atattttccg tgcccgggta
    23941 gcgggaaacg atttcggccc gatggagaac ctaggagaag agatcaacac gccgggagac
    24001 gagatgttcc cgtatgtccg ggattccgtc accctttatt tcgcgtccaa cgggcatccg
    24061 ggaatgggcg gtctcgatct gttcaaggcc acgcaagaca gtacggggaa gtggaatgtc
    24121 gagaacctag gagcccccat caattctatg ggagacgatt tcggtatcac cttcgccgga
    24181 aaagaggaac ggggcttctt ctgctccaac cgcaacgacg cacggggcta tgaccatatc
    24241 tattcctttg aactgccgac gatcaccatc ttcatcgaag gaatcgtaaa cgatgtcgat
    24301 gaatatccga tcgaggacgc taccgtacgc atcgtcggaa aagacggact gaacgtgaaa
    24361 gtcccggtca agaaagacgg tacctatcgt gtcgagttgg aacgggacat ccgttatgtc
    24421 atgatggcca gcgcccgtgg ttacctcaac cagaattatg aattgcatac cggccccgag
    24481 gagaaaaacg agacatatat cgtggatttc ttcctctctc cgatcagcaa gccggttgtt
    24541 atcgataaca ttttctacga tttcgataaa gcgacccttc gtccggaatc caagaaagct
    24601 ttggacgaga tgatcaagat gctgaacgat aacccgaacg taacgatcga actgggtgcc
    24661 cacacggacc ggaaaggtac ggaccagtat aacgagcgtt tggctcaacg ccgtgcgcaa
    24721 tcggtcgtgg attacctaat agcgggaggt atcgaggcgg ctcgtctgga agcgaaagga
    24781 tatggagaaa gcgttcccaa gacgatcaac aagaagatgg ctaaacaatt cgatttcttg
    24841 aaagaaggcg atgtgcttac cgaggaattc atccttgccc tgccgccgga acagcaagag
    24901 atcgccgacc agatcaaccg cagaacggaa ttcaaggtct tacgtacaaa ctataactta
    24961 ttttgaagga gcaaagagcg tgatctcctt aaaagagacc ggccaatcga tcgcactcat
    25021 cagcacatcg aaggacaggc gttgctgata agagaccgag gactcccttg aatacaagtc
    25081 atgagctacc aaaccgatca tcatcttaac cttataatgc aattccttgg atagtaccaa
    25141 gcaggcaagt acactcaaat ctctcgcttc ttcccaatcc cgatccgcaa aacacatctc
    25201 cctttgaagt gccggataat gacgagtccg catgatcaga tccggatcac ggacctcaca
    25261 cgcaccttcc actacatcca ataatatacg acagacagcc aaacgttgct ttttaattac
    25321 ctccatatac gtttccctca aaccggaccg ttcaccttgt tcggtatttc tatatgctac
    25381 aaaaaagaag cgtgggaact gttaatctac tattcgaaac tgaggcatcg ccaaacaccc
    25441 atcggacaaa taataaacaa cagcccacgc cttattacgt atactattag gcagtatata
    25501 taacaagcgt gagcgtttag ttgcctatta tctctgtccg acttgaaact tggcgatttt
    25561 cagttccaaa gataatatct taaacgctta tcgtaatcac actttgattc ataaaccctt
    25621 gaatttccac aagagtttac tttatcgata caaatataac gctttttctc atacatcata
    25681 tggatttatt tttctctttt aaaatctatt gggaaaagat agcgtatact ctctagcgat
    25741 aaattcttcc actataaaca agatgcttcc gtgagtaaaa aagagaagcg catatacata
    25801 ctattcaatg tatatgcgcc tccaccatta tttggatatt tccaaatccg gaactttctt
    25861 ccttatttac tctaccgaga acttataaat acactcactc gtatatttct cgcccggacg
    25921 taggatgaca ctcgggaaag aaggttggtt cgggctatcc gggtaatgtt gagtctccag
    25981 acatagagcg ccacgatgtg ggtaaaccac acctaacttg cctttatcac ccgctttcgt
    26041 cattgagttg ccggcataga attgaagacc cggctcgttg gtgtaaactt ccataacgat
    26101 accgcttgtc ggagatacaa ctttagcggc taccttattg atatcgccgg c
//
LOCUS       DBMDTB010000057        25672 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_676_length_25672_cov_13.281217, whole genome shotgun sequence.
ACCESSION   DBMDTB010000057 DBMDTB010000000
VERSION     DBMDTB010000057.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 25672)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 25672)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25672
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_676_length_25672_cov_13.281217"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            289..526
                     /locus_tag="ACZPB4_10300"
                     /pseudo
     CDS             289..526
                     /locus_tag="ACZPB4_10300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004302149.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
     gene            1435..2340
                     /locus_tag="ACZPB4_10305"
     CDS             1435..2340
                     /locus_tag="ACZPB4_10305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HIR1098636.1"
                     /translation="MPELISIEEAARITGFPYEEIEDWVKSRKITSFHTRTGTRMVDP
                     ENLRDFIAHIEHLGIQKLYLQLVIQDKEEEADEIIAQYDDYLFCLQSLKNISPLLKQI
                     IAELSTFIDDKQDRYIFTEITSGAKILDVAKRCDISYDRMCYRYKNIVLRLQENTGFL
                     AEYKKTISCQDLEIERLRLEKRNMEYELRTLYKAVLKSGLSLDAPKSSFDIPTDAARR
                     ISLPVTSLTLSPYIRKCLQKLELETMEDLLRYARKKGLDSLLKIPGFGPLGLDQLKFQ
                     LEKHKIMNKAGDSDLYQYIINEPDS"
     gene            2858..4171
                     /locus_tag="ACZPB4_10310"
     CDS             2858..4171
                     /locus_tag="ACZPB4_10310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin"
                     /protein_id="HIR1098637.1"
                     /translation="MRTLTNLLAIGLLSFTALHAQESNMSSTVKASEMYADGFSKFRF
                     GGYGEMAASYMDYDWNWVTPQGTSHMNRATVSIPRFILAFDYKFSPKWVLSSEIEFEY
                     GGTGAAREVEWYEENGEYETEIEKGGEVALEQFHISYLMNKHLNFRFGHMIVPVGLTN
                     AHHEPLNFFGVYRPEGETTILPSTWHETGVALFGDLGNFDYELQVVSGLDPQGFRMEN
                     WVGKGTQGAFEETQFTHPAFVARVNYNGVKKFKGLRVGASFYYNQPSKNSSKPLRNQG
                     EKYPLTIVTADAQYKSPNNNLIARGNIVYGHLGNSNALTKVNNNSSSASGYPNSTVAE
                     TAVSYAAEVGYNVGSFFSRKAPRIYPFVRYEYYNPMQSVEKGSNKLADRRLQKSVITA
                     GLNYYALPNLVVKADYAHRIVGKGDYNSQNMVSVGIAYIGWFLSR"
     gene            4202..5413
                     /locus_tag="ACZPB4_10315"
     CDS             4202..5413
                     /locus_tag="ACZPB4_10315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imelysin family protein"
                     /protein_id="HIR1098638.1"
                     /translation="MKKVLLLPMMLMGVALSFTSCGDNDDPGKDPDVVTYDFKNLPAD
                     SGAKPTEDQMSAVVATFVDEVALPTYKDMLTKMTAYKNAVDKFIASGSKNDLADACDA
                     WRAVRVPWEQSEAFLFGVADLAQLDPSLDSWPLDKNGIEEIIATGEFSKISGAVDEDA
                     EDGPQNLRGFHTAEKMLFLDGEPRDLETSPFAKNELEYLKLVSERMLSDTQDLYNGWL
                     KGLGTSDVPSSYAEAMKKHDGSAYSIGNVYQAIELMLNGNNGMAGISNEVGSAKITDP
                     VTAWNGSNKDATDPNNPGVLAVESWYSWNSLDDYKNNIVSIKNAYFGGRDLDEESASE
                     SSLHALTKMINPTLDSLMVVQIDKTIDAINAIGYPFRNNLGDTEHINTATEACADLTT
                     GLGVVKSKFTN"
     gene            5431..6837
                     /locus_tag="ACZPB4_10320"
     CDS             5431..6837
                     /locus_tag="ACZPB4_10320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="di-heme oxidoredictase family protein"
                     /protein_id="HIR1098639.1"
                     /translation="MKRRLLLLFALSGSLLCSCESEDLENWQVKKPNGQVASEKELSA
                     GISTIFSNAPDAYDTQANWVTGELETRFNRGDGLYDDARGVENVDGGGLGPLYAGYSC
                     GSCHKSTGRTRPAIADGGSGPGFSSMLIYISRKSGGYFQDYGRVLHDQAIYGTKPEGR
                     VKITTTSQKYTFPDGEEYELVTPHYEIKEWYADSIPMSDLRISVRQPLRHVGMGQMMA
                     LDLDMLKQIAAKSNYPEYGISGRINYVTEKGKKQIGISGNKANHADLTVELGFSSDLG
                     VTNDRFPHEVGEGQGNMMGFAMTGAQVSTEDMEDVDLYLQTLGVPARRNVDDPTVLQG
                     EQLFYQAKCHLCHVTSLKTRPRGSVLLNNTELPQLGNQVIHPYSDFLLHDMGVELGDD
                     YPSGLANGNEWRTTPLWGLGLQEVVNGHTYYLHDGRARNLTEAIMWHGGEGAASRTLF
                     SRMTKDERAALIKFLQSL"
     gene            6860..8095
                     /locus_tag="ACZPB4_10325"
     CDS             6860..8095
                     /locus_tag="ACZPB4_10325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007748002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin"
                     /protein_id="HIR1098640.1"
                     /translation="MKKIYRTLLVVLLSAGVFSVKAQDTKKEMDDKYVENDVVSLAGK
                     KGFSFSTKAGDFLFKPYALVQASACYNRYDDQGLESHYAKSVANSGFAIPNAILGFTG
                     KAFGRVTFNLSLNAAKSGGALLQQAWFDVAIKESFRIRVGKFKTPFMHGYLSTLGETL
                     FPVLPYSASQSVLLPYDVNYVIPNMSTGFDLGVQVHGLIHDKWNYQVGIFNGTGIDVN
                     LATKTNCDDHKWLPSLLYAGRLAFMPKGEMPTSQGSPENLNDDKMSIAVSASYNAEAE
                     FLTSSDTRVGVEFAWIKNRWYVAAEGYYMNMHFTKIMQKPDKNFWGAYAQLGYFITPK
                     LQGALRYDFYDRNATDEGGLLNMPAAGLNYYFFNNNLKLQVMYQYLGRSGHATQNDRD
                     EDAIGLARHSATAMLQFTF"
     gene            8105..8812
                     /locus_tag="ACZPB4_10330"
     CDS             8105..8812
                     /locus_tag="ACZPB4_10330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098641.1"
                     /translation="MKRYSQYIMYALFLLFGLGCDEGKIYPDETVDSGRTATVSLSFT
                     GLKAWPKENMLSLCAFGEDKSKPLQTQRISKPAEDGKRLKLRLNNVTPDTRSIEVAVI
                     SRGLRLVYSYYTSPVDDSDEPLDLSVGELDLASFKRIQAQVFDLNCLSCHGGGSGLAG
                     QLDLRDDVAYKSLVNVKAPLSEEGKNYVTPGNINNSFLLDILENNPVHKDMFNSSGKQ
                     EVLALIQGWILGGALDN"
     gene            8824..9978
                     /locus_tag="ACZPB4_10335"
     CDS             8824..9978
                     /locus_tag="ACZPB4_10335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rid family hydrolase"
                     /protein_id="HIR1098642.1"
                     /translation="MMNYTRRIDTDKAVEMQISSFTGKGGTTEYQVMVSITDPCLSFV
                     EQLQNLLRVYVTVVKEELSNDATAVFRRYFLSDAANQTDSVMEWECESAFCPLSIVQQ
                     PPLNGTKIAMWTYLQTGMSVQTYDSGLLEASHNGYRHLWGGGAFNKAANSEYQTRLLL
                     NDYVMQLMGQRCTLASHCVRTWFFVQNVDVNYAGVVKARKEVFITQNLTEKTHYIAST
                     GIEGRHADPSVLVQMDSYAVDGLEPGQIQFLYAPTHLNPTYEYGVTFERGTAVTYGDR
                     KQVFISGTASIDNRGEIVYPGDIVKQTERMMENISVLLKEADATTRDITQAISYLRDM
                     ADYAVVKKYFEAHYPDLPHLIVLAPVCRPGWLIETECIAVVPTESSFKPL"
     gene            10061..10750
                     /locus_tag="ACZPB4_10340"
     CDS             10061..10750
                     /locus_tag="ACZPB4_10340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010185248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemerythrin domain-containing protein"
                     /protein_id="HIR1098643.1"
                     /translation="MYKNGMYRETDKMSDLICENYPMVLVMSRFGIALGFGEKNIGEV
                     CRQNGVDACTFLTVVNFLVEEVNTPVENISKCLSIENLIRYLHNAHDYFLNFRLPHIR
                     RKLVDAISGCPEDVAFVITKFFDEYAEEVNKHMSYEERAVFPYVRNLLEGKRDPKYNI
                     TIFRKRHDQIEMKITELKNILIKYYPGAGTNMLNSVLFDIFATEEDLASHTRVEDYLF
                     VPAILALEKQL"
     gene            10761..11372
                     /locus_tag="ACZPB4_10345"
     CDS             10761..11372
                     /locus_tag="ACZPB4_10345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HIR1098644.1"
                     /translation="MSTNLKIAIAEPSVIIRSGLENLLKRLPGFRIQMVEIHSVESLF
                     DSLRMHKPDVLIVNPALPGYFTLQHLKEESGCAEMKCIALLYSVSDSVLLRSYDEQIN
                     IYDSPDEIKHKLERLNAEVLPDDEPEGDDEQQSLSSREKEIVVCVVKGMTNREIADRL
                     FLSTHTVITHRRNIARKLQIHSASGLTIYAIVNKLVELGDIKQ"
     gene            11544..12110
                     /locus_tag="ACZPB4_10350"
     CDS             11544..12110
                     /locus_tag="ACZPB4_10350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3575 domain-containing protein"
                     /protein_id="HIR1098645.1"
                     /translation="MKKAFLLGLALLFSLSMSAQHFALKNNLLYDATTTPNLGFEVGL
                     SKKVTLDVSAGYNPFKFNDGKKLKHWLVMPEVRYWTCEKFNGTFIGVHALGGQYNIAG
                     IKLPFGIFPNLKDHRYDGYLYGGGLTLGHQWILNKRWSIEAAIGAGYARVHYDKYNCG
                     ECGSKIETKNSNYWGVTKAALSIIYFIH"
     gene            12129..13577
                     /locus_tag="ACZPB4_10355"
     CDS             12129..13577
                     /locus_tag="ACZPB4_10355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3868 domain-containing protein"
                     /protein_id="HIR1098646.1"
                     /translation="MRHLLSICIALLFLGGVSLQAQNGVRGTVSFENVSAKKDGSQLM
                     MNFTTNLSNLRLKSQEMVILTPVLQSVDKSQSYQFNPIVITGRARMKALNRELGFDSY
                     EFPQTPSLIIRQTKKGPELIPVELSVPYAGWMRNATLMVDENTTGCASCEVSNDIYGV
                     MSRVLPPLAPPVYELSYVTPPVEPVKQRSETHSAYLNFEVGKSVLLRDFKDNATVLNE
                     VNKIVTEVRNDKNLSFTEFKVTGYASPEGGYDYNMRLSESRAKAFVAYMKDKEKMDPS
                     LMKVNWMGEDWIGLRQEVTKSDLANKKEILEILDIQDINKRKAKLHALNGGRTYKILL
                     DKYYPPLRRIDYTLAYIARPFDVNEAKQVIKTKPQYLSLNEMFLVANSYDKGSDQFKE
                     VFDIAVRLYPTDPIAQLNTAALEIETGAYDPAISRLQGINLPEAWNNLGVAYAMKKDY
                     TTAMQYFDQAAQAGMQDAAANRDELAAWLAEQ"
     gene            complement(13637..14707)
                     /locus_tag="ACZPB4_10360"
     CDS             complement(13637..14707)
                     /locus_tag="ACZPB4_10360"
                     /EC_number="1.13.12.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004497 - monooxygenase activity [Evidence
                     IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016703 - oxidoreductase activity, acting
                     on single donors with incorporation of molecular oxygen,
                     incorporation of one atom of oxygen (internal
                     monooxygenases or internal mixed function oxidases)
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent flavin oxidoreductase"
                     /protein_id="HIR1098647.1"
                     /translation="MKTLTIGDLKARIPIIQGGMGVGISLSGLASAVANEGGIGVISA
                     AGLGLLYKKLSPSNYTEAGNLGLAEEIRKAREKAKGIIGVNVMVALSDFAELVKTSIA
                     EKVDIIFSGAGLPLDLPSFLKKDSVTKLVPIVSSARAVRIICEKWKNNYDYLPDAVVL
                     EGPKAGGHLGYKENQLEDQHFSLEELLPQVVEEVSHFEQKYDKKIPVIAAGGIYTGED
                     IKRMIDLGASGVQLGTRFVTTTECDASEAFKQTYIQAEEKDIEIIKSPVGMPGRAIHC
                     SFLEKVKAGIKQPKACPFNCIKTCDISRSPYCIVTALYNAFKGNFENGYAFAGSNAWR
                     ANKITSVRETITELMNEWKAKL"
     gene            14963..16249
                     /locus_tag="ACZPB4_10365"
     CDS             14963..16249
                     /locus_tag="ACZPB4_10365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098648.1"
                     /translation="MKLGKVIALMLVLLPFSMGAQEVDQSVEKHIDSLATEVTTLDKV
                     VQKLSKFKVSAYIQGQYQYGQEDATLKVGDKNENLDKGFNRIGIRRGRMKFEYNDGIG
                     TGAVQIEVNDKGVSFRDLYIGIKDPWTKRSQLMAGVFNRPFGYEVCYSTSSLESPERA
                     TIIQYFFPDERDLGAMLTLRTKTTSPLSFLRLDAGLFAGNSINRETDSRKDFIGRLGA
                     EKAIGDWGKWGAGFSYYHGFVYNPTTEAYEMRGNHFVKRDMGETGTYMKRQYLGLDGQ
                     FSFLSSLGKTTLRAEGLIGTQPGIAGSSKSPNYSTRPENLPENSLFKRPFLGYFFYLV
                     QDIGASPFSAVLKYDVYDPNTKVSGNEVGAENSFTSKTDLAQSTIGIGGIYNFNKHIR
                     LQAYYEFNFNEKSNLVKGYENDRKDNVLTVRLQYKF"
     gene            16335..17153
                     /locus_tag="ACZPB4_10370"
     CDS             16335..17153
                     /locus_tag="ACZPB4_10370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009859744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042301 - phosphate ion binding [Evidence
                     IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PstS family phosphate ABC transporter
                     substrate-binding protein"
                     /protein_id="HIR1098649.1"
                     /translation="MKKTILLAAMAACLFATNVFAQKIKGSDTCLPLTQTEAENFMNK
                     NKAAKITVTGGGSGVGISALMEGTTDIAMASRKMKFDERMKLQEAGKKTKEEVIAYDA
                     LAVVVHPSNKVSNLTREQLEGIFTGKIKNWKEVGGADMKIVAYSRETSSGTYEFFKES
                     VLKNKNYMNGILSMPATGAIIQSVSQTKGAIGYVGLAYLNKEVKPIHVSYDAGKSYVE
                     PSLENARNKTYPVVRPLFYYYETKNASKVRPFIDYVMSAEGQATVKKVGYIPVK"
     gene            complement(17247..18026)
                     /locus_tag="ACZPB4_10375"
     CDS             complement(17247..18026)
                     /locus_tag="ACZPB4_10375"
                     /EC_number="3.6.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008758 - UDP-2,3-diacylglucosamine
                     hydrolase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-2,3-diacylglucosamine diphosphatase"
                     /protein_id="HIR1098650.1"
                     /translation="MKIYFASDAHLGARFHKDPLAIEKKLVRWLDSIKEDASAIWFLG
                     DLFDYWYEYKYVVPKGHVRFLGKLAELADRGIEIHIFIGNHDIWMFDYLPKEIGAIIH
                     RDTLTVDLLGKRFFLGHGDEVDFRSKAFRLIRAIFRNKFCQWLYAGIHPRWTFGFALG
                     WSLNSRKSGLEKQEAKKYQGEDAEYMVVFAKEYLKTHPDINFFIFGHRHIMLDLMLSR
                     TSRILIAGDWMQFFSYIVWDGENLYMDQFLEETDGQSYPNT"
     gene            complement(18023..18340)
                     /locus_tag="ACZPB4_10380"
     CDS             complement(18023..18340)
                     /locus_tag="ACZPB4_10380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008146258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HIR1098651.1"
                     /translation="MNNEFLQTEEAIVAMLKTVYDPEIPVNVYDLGLIYKVDIDEEKN
                     VRIDMTLTAPNCPAADFILEDVRMKVEAVDGVNNVEVNLVFEPEWDKDMMTEEAKLEL
                     GFL"
     gene            complement(18412..19119)
                     /gene="radC"
                     /locus_tag="ACZPB4_10385"
     CDS             complement(18412..19119)
                     /gene="radC"
                     /locus_tag="ACZPB4_10385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RadC family protein"
                     /protein_id="HIR1098652.1"
                     /translation="MKEKTGKLSIKEWAEEDRPREKMLQKGASVLSDAELIAILIGSG
                     NNEETAVQLSQRILHSVNNNLNTLGKRSIKELTSGFKGIGEAKAVTICAAMELGKRRE
                     TSEASPQDAIRSSKDSYLLFRTQLCDLPYEELWIALTNPLNKVIQKVKISQGGVNQTS
                     VDIRLVLKAAINALASGIILCHNHPSGSLRPSTHDDALTERIQKAAKLMDIRILDHII
                     LSDSGYYSYADEGRLIR"
     gene            complement(19205..19771)
                     /gene="efp"
                     /locus_tag="ACZPB4_10390"
     CDS             complement(19205..19771)
                     /gene="efp"
                     /locus_tag="ACZPB4_10390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HIR1098653.1"
                     /translation="MINSQDIKKGTCIRLDGKLYFCVDFLHVKPGKGNTIMRTTLKDV
                     VKGGQIERRFNIGEKLEDVRVERRPYQFTYTEGEHYHFMNQETFDDVIIDKNLINGVD
                     FMKEGEIVDVVSDASTDTVLFADMPTKVQLKVTYTEPGIKGDTATNTLKPATVETGAE
                     VRVPLFINEGEVIEINTTDGSYVGRIRE"
     gene            complement(19871..20575)
                     /locus_tag="ACZPB4_10395"
     CDS             complement(19871..20575)
                     /locus_tag="ACZPB4_10395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HIR1098654.1"
                     /translation="MDNLAHSEIFALTLVIGTYLTSLALYKKVHISLLHPLLTTIFVI
                     IVVLEVLGIQYESFQQSSHLIHFMLGPSVVALGYVLYEQIQYLKGNVVSILTSVFVGA
                     IVGIVSVIIIGKLMGADQALIATLQPKSVTTPIAMGIAEKAGGIPSLTAVIVVAVGIF
                     GSIVGPIVMRVLGIDSHIAKGLALGASSHGVGTAAAIQIGAIEGALSGLAIGLMGIMT
                     AVLVPVIRLICNYFSI"
     gene            complement(20579..20917)
                     /locus_tag="ACZPB4_10400"
     CDS             complement(20579..20917)
                     /locus_tag="ACZPB4_10400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HIR1098655.1"
                     /translation="MLTEAFYILFFYFTGEFISYFIDGFIPGSVIGMVLLFLALAFKK
                     VKPEKVKRLSTVLTQNMGLFFVPAGVGLMNSFGIISEYWAVLLIASVVSTILVIASVA
                     LVQQKLEKGK"
     gene            complement(21029..22375)
                     /gene="mgtE"
                     /locus_tag="ACZPB4_10405"
     CDS             complement(21029..22375)
                     /gene="mgtE"
                     /locus_tag="ACZPB4_10405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015095 - magnesium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HIR1098656.1"
                     /translation="MIELTKDYIENLKSIIEAKDDAKAQEVLHELYPADIAELYQELN
                     LQEAIYLYLLMDGDKAADVLMELDEEDRHKLLKELPNELIAKRFVDNMETDDAVDLMR
                     ELDEDTQEEILSHIEDVEQAGDIVDLLKYDEDTAGGLMGTEMIVVNENWSMPKCIDEM
                     RKQAEEMSEIYYVYVVDDDERLKGVLPLQKLITHPSVSKIKHVMKKDPISVRDSDSIE
                     EVTETIEKYDLVALPVVDSIGRLVGRITIDDVMDEVREQHERDYQLASGISQDVETSD
                     NVFTQTAARLPWLLIGMIGGLGNSVILGGFESSFATNPKMALFIPLIGGTGGNVGIQS
                     SAIVVQGLANNTLKEGNIVPQILKESVVSLINASIISLVVFIYNFFMLGDRGITASVS
                     LSLFAVVMFASIFGTLVPMTLDKMKIDPALATGPFITITNDIIGMMIYMFITSALA"
     gene            complement(22391..23191)
                     /gene="rsmA"
                     /locus_tag="ACZPB4_10410"
     CDS             complement(22391..23191)
                     /gene="rsmA"
                     /locus_tag="ACZPB4_10410"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0000154 - rRNA modification [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HIR1098657.1"
                     /translation="MRLVKPKKALGQHFLKDLQIAQRIADTLDTFKSLPVLEIGPGMG
                     VLTQFLLEAGHDLTVVELDMESVDYLNQNFPDLKGRIIAEDFLKLDLSKLFPGQFCVI
                     GNYPYNISSQIFFKVLDYKDQIPCCSGMLQKEVAERLAAGPGSKTYGILSVLLQAWYD
                     VEYLFTVSEKVFDPPPKVKSAVLKMTRNDRKELGCDEKLFKTVVKTSFNQRRKTLRNS
                     MKPLLGKDCPDYALPIFDKRPEQLSVEQFVELTLISQKHLEKQAGDVL"
     gene            23287..24300
                     /locus_tag="ACZPB4_10415"
     CDS             23287..24300
                     /locus_tag="ACZPB4_10415"
                     /EC_number="2.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysylphosphatidylglycerol synthase transmembrane
                     domain-containing protein"
                     /protein_id="HIR1098658.1"
                     /translation="MDFKSILRTFLKIILPLAFGCLLLWFLYRKMDITEIWRVVKEGV
                     RYDIILVSLLFGLFANIVRGLRWGLLISSLGERFKMSNVIYAVLGNYAVNLVLPRVGE
                     VWRCGMITKYDKISFTKLLGTLLIDRVSDTIMVGLITLMIFIFNISFFTSFFAKNPAL
                     LEGFQSMFNSIWIYVAVIIFVAVIWFVFTYMSNFTLVQKAKGMLKNIWTGMKSIWYME
                     HKMRFVIETLLIWGGYFCYFYITFYAFDFTKDLGIVVGLITFTMSSIGVAVPVQGGIG
                     PWHFMVIATLVCFGVNENDAAAFALVVHTVQTVWTGLCGLFGVVALPLTNRENKEAPV
                     AVS"
     gene            24351..>25672
                     /locus_tag="ACZPB4_10420"
     CDS             24351..>25672
                     /locus_tag="ACZPB4_10420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-histidine dipeptidase"
                     /protein_id="HIR1098659.1"
                     /translation="MSAEIKDLSPKHVWGYFYDLTQIPRPTGHMEAVTRFMISFGKGL
                     GLETLQDEVGNVLIRKPATPGMEGRKTVTLQSHLDMVPQKNSSVKHDFEKDPIDAYID
                     GDWVTARETTLGADNGMGAALAMAVLADNSLRHGPIEALFTIDEEQGMDGAFGLKPHF
                     LQGDILLNCDSEKEGELFVGCAGGANVNVSFQFKEDTYIPEGDVAVKVSLSGLKGGHS
                     GVDIHLGRANANKLIFRFLKEAVCDYGARLSSVAGGSLPNAIPREAFAVITIPGDNVE
                     SLWELVADYQDMFRTEYMGVEDQIDFVAEMVELPSTLIPEEIQDDLINAIEGCQNGVI
                     SMLHDFPGTVESSSNLAIVKTSDELIEVKILVRSSSESRRDSVCSSLESVFALAGAKV
                     EESGHYNGWQPNINSPILNLMKSTYLDLFGKEPEVKVMHAGLECGIIQG"
BASE COUNT         6826 a         5291 c         6311 g         7244 t
ORIGIN      
        1 tcgaatgatg ctgtaaaaag tcgtacgtgt ttcccgaaaa acatgtacga ctttttacag
       61 aaacacgtac gtgtttttca aaaatcacaa tcgtgttttt taaggtgttg atattaagca
      121 atttatatat ttgtgccatt tgtatacctt attgtatatt attattacca agacggaaca
      181 cgcactgcct atacaagagt gggtaatatt gatattgaag ggtatgcaca tgacatggga
      241 ttcacttcct acccaagtgg atgccagcaa acattcttgt aaatgaagaa aagttcggag
      301 agtgagttcg gagacactgc ggataagcct aaaaatatag gtagaacagc acagaagatc
      361 atcgaccttg tcatttccga cctttctatg tcagccgaag ctatggctta taaaattagg
      421 tataagttcc cgtgctgtag aaaaacaaat cgcaaaattg cgttctatgg gtatattgtc
      481 tcgtgaaggc gcagactttg gtggttattg gcgtattatt ttaagttacc attttgaggg
      541 gatgagacgc agcacgctgc gtctctacaa ctggagacaa aattgggcga aaaaagtaag
      601 ttagcttgct ttggaagtga ggtattggag tttgaaaatc aaataaaata ttatacattt
      661 gcatgactgg ataagtcaaa gcgaataatt ggtatcaaac aatgataaac taaaaaacat
      721 atggattatc ttaggttgaa atattattaa tacgtatatt tgcgacaaga aaaggctttt
      781 taattaagag cctcgtgttg cgtgtgatat ttgtgctgta ggacgaaaat cggctaattt
      841 tcttaaatct ccctatgcac gaagaaggcc ccgcaaccct ttactggata tacgtgttat
      901 ctatgctaat atagtatgga tatattttgt atacagataa agggggcgtg tggctgactt
      961 tattgggagt tgggtcttag ccgaaccttc gtctacataa atgttcagtc ctcgcccttc
     1021 ctttatttta taagaaagga ccactactta acaaaagcca tatagcgctc gtctttacga
     1081 aggacatctt ttctaaaaca tgtctggatc ttgtaaatct aataattaat catgtaaagt
     1141 gaatggctta tggacgcttg taatattgat gagatccaga atctctttat ttactactcc
     1201 gcttgtttca gcaagtattt tccagagtta gggttttatt gtaatgagag ggaattccag
     1261 atacatggta tcgtgcggag atatagtgac attacgggag tgtcccatga tggctcttat
     1321 ttcttaattg agatgcgaaa agaatacctg atctacttac cgttattggt cggttccaaa
     1381 ttccgcattt taactaaaca aaaacaactt tattcgtaat acaatcttat gcttatgcca
     1441 gaactcatat ccatagaaga agccgcccgt attaccggtt tcccgtacga ggagattgaa
     1501 gattgggtaa aatcccgaaa gataacctct ttccatacga gaaccggtac acgtatggta
     1561 gatcctgaga acctacgtga tttcattgcc catatcgaac atctagggat tcaaaaacta
     1621 tacttgcaac tggtcattca agacaaggag gaggaagccg acgagattat cgcccagtac
     1681 gacgattacc ttttctgcct acaatcctta aagaacatct ctcccctact taaacaaatc
     1741 atcgccgaac tatccacatt tatagatgat aagcaagatc ggtatatatt cacggaaata
     1801 acctctgggg caaaaatact ggacgtagcc aaacgctgcg atatatctta cgataggatg
     1861 tgctaccgat ataagaacat agtactccgc ttgcaggaaa acaccggatt cttagccgaa
     1921 tataagaaaa cgatcagctg tcaagaccta gagatagagc gcctgcggct tgagaagcga
     1981 aacatggaat atgagctgag aacgctctat aaagcagtcc tcaaaagtgg cttgagtctc
     2041 gatgctccga aatcgtcgtt cgacatcccc acggatgcgg ccagacggat ctccctaccg
     2101 gtcacaagcc taaccctgtc tccctacatc cgtaaatgcc tccaaaaatt ggagctggaa
     2161 actatggagg acctattgcg ctacgctagg aagaaagggc tcgattcttt gttgaagatc
     2221 ccgggattcg gccctctcgg tttagaccag ttaaaatttc agctggaaaa gcataagatc
     2281 atgaataagg ccggagactc ggatctctat caatacatca tcaatgaacc ggatagctga
     2341 acacaaaaag agcctctctt cacagggagg ccctttttat gtgatgccgg aaataaccaa
     2401 taaaaacttc ccgacactac ggtgttaatc atcttatatg cttacataaa attagcagaa
     2461 ggctttggtt tgcgatatac taatagtgtt acattctttt tgacattgca aagatacgtc
     2521 ggcctataag ggtgcgcaat acctatatat atgtaaaaaa ggagagctca tacctattaa
     2581 ttgttatata tcttttcatg gagatcgatt tttagaacta atgatcttct cgcttgtaat
     2641 aactaacgct tacctctgaa ataatacaaa accgtatttt ccaaaattaa ctatcaagtt
     2701 gtcttgcggg tcaataatgg ggcctattcg gtatgacgtc ttgaaaatat tcttccggga
     2761 tacctatgag taggtaatta gggtctcatt ttacctactt cgggcgattg tagcaaattc
     2821 tcagcccctg taattttgcc aaaaattata aaacgcaatg agaacgttaa caaatttatt
     2881 agcgattgga ttactttcct ttaccgctct acatgctcaa gagagtaata tgagctctac
     2941 cgtaaaggca tcggagatgt atgccgacgg tttttctaaa ttccgttttg gaggatatgg
     3001 tgagatggct gccagttata tggattatga ctggaattgg gtgacacctc aaggtacatc
     3061 acatatgaat cgggctactg tctctatccc tcgttttatt ttagcttttg attataagtt
     3121 ctctcccaaa tgggtactga gttccgagat tgagtttgag tatggaggaa caggcgccgc
     3181 acgggaagtg gagtggtacg aggagaatgg agaatatgag accgagatcg agaaaggtgg
     3241 cgaggtcgcc ttggagcagt tccatatctc ttatctgatg aacaagcatt taaacttccg
     3301 ttttggacat atgatcgtac cggtaggctt gaccaacgca catcatgaac ccttgaactt
     3361 ttttggtgta tatcgtccgg aaggagagac taccatatta ccttctactt ggcatgagac
     3421 gggtgtggct ctatttggtg atttaggaaa tttcgattac gagttacaag tcgtttccgg
     3481 tttggaccca caaggtttcc gtatggagaa ctgggttggc aaaggtacgc aaggcgcttt
     3541 cgaggaaact caatttacgc atcctgcctt tgtggctcgt gtcaactata atggagtgaa
     3601 gaaatttaaa ggcttacgtg tgggcgcttc tttttattat aaccaaccct ctaagaatag
     3661 tagcaaaccg ctgcgtaacc aaggtgagaa atatccgctt accatcgtga cggcggacgc
     3721 tcaatataaa agtccgaaca ataatttgat cgccagaggt aatatcgttt acggccatct
     3781 gggcaacagc aacgctctga cgaaggtaaa caataactca tcttcagctt ccggatatcc
     3841 taattcaacc gtggcggaga ccgctgtcag ttatgcggct gaggttggct ataatgtagg
     3901 ttccttcttt agtcggaaag cccctagaat ttatcctttc gttcgctacg aatattataa
     3961 tccgatgcaa tccgtagaaa aaggcagtaa taaactggcg gatagacgtc ttcaaaagag
     4021 cgtgattacg gctggcctta actattacgc attgcctaat ctggtcgtaa aggcggatta
     4081 tgcgcaccgt attgtaggta agggtgatta taatagccag aatatggttt ctgtcggtat
     4141 cgcttatatc ggctggttct tatcaagata atagactatt aacaaatata tatgtaagaa
     4201 tatgaaaaaa gtacttttat tacccatgat gttgatgggt gtggctttga gcttcacttc
     4261 ttgtggagac aacgatgatc cgggcaagga ccccgatgtt gtaacttatg actttaagaa
     4321 tcttcctgcg gattcgggtg caaaaccaac agaagatcag atgagtgcgg ttgtcgctac
     4381 tttcgttgat gaggtagctt tgcctaccta taaggatatg ttgacaaaga tgactgccta
     4441 taaaaatgcg gtagacaagt tcatcgcgtc tggttctaag aatgatttag cggatgcctg
     4501 cgacgcttgg cgtgcggttc gtgtaccttg ggaacaaagt gaggcattct tgttcggtgt
     4561 ggcggatttg gcacagctcg acccgagctt ggatagctgg cctttggata agaacggtat
     4621 agaggagatt atagctacag gagaattcag caagatttca ggagctgtag acgaagacgc
     4681 ggaagatggt cctcaaaatt tacgtggatt ccatacggcg gaaaagatgt tattcttaga
     4741 cggcgagcct cgtgatctgg aaacaagccc gttcgcaaag aatgaattgg agtatttgaa
     4801 gttagtgtcc gaacgtatgt tatctgatac tcaagactta tacaatggtt ggttgaaagg
     4861 cttaggaact tcggatgttc cttcttctta tgcggaggct atgaagaaac atgacggttc
     4921 tgcctattcc attggtaatg tttatcaggc gattgagctt atgctgaatg gaaataatgg
     4981 tatggccgga atctccaatg aagtaggttc cgctaagata actgacccgg tgaccgcatg
     5041 gaatggaagt aataaagacg ctactgaccc gaataacccc ggtgtcttgg ctgtagagtc
     5101 ttggtatagc tggaattcct tggacgacta taagaacaat atcgtaagta tcaagaacgc
     5161 ttatttcggc ggtcgtgatt tggatgagga atccgcttcc gagagtagct tgcatgcgtt
     5221 gactaaaatg attaatccta cgttggatag tttgatggta gttcaaattg ataagacaat
     5281 cgacgctatc aatgcgatcg gctatccttt ccgtaacaat ctaggggata cggagcatat
     5341 caatacggct acagaagctt gcgctgattt aacgacaggt ttgggcgttg ttaagtctaa
     5401 gttcacgaac taatcggaca agccgatacg atgaaacgaa gattacttct attattcgct
     5461 ttatccggta gtctgctgtg tagttgcgaa tccgaggact tggaaaattg gcaggttaag
     5521 aaacccaatg ggcaggtagc ttccgagaag gagttgtccg cgggtatctc aaccattttc
     5581 tccaatgccc cggatgcgta cgatacgcag gcaaactggg ttacgggcga attagagacg
     5641 cgatttaatc gtggtgatgg attgtacgac gatgctcgcg gtgttgagaa tgtggatggt
     5701 ggaggactag ggccgcttta tgccggatat tcttgcggtt cctgtcataa aagtaccggg
     5761 cggacccgtc cggctatagc tgatggaggt tccggccccg gcttctcatc catgcttatt
     5821 tatatatcac gtaaaagtgg cggctatttt caagattacg gccgggtact acatgatcaa
     5881 gcgatatacg gaacgaaacc ggagggaagg gttaagatta ctactacttc ccaaaaatat
     5941 acgtttcccg atggggagga atatgagttg gtcactcctc attatgagat aaaagaatgg
     6001 tatgccgata gtatcccgat gtcggattta cggatttccg tacgtcaacc cttacggcat
     6061 gtcggaatgg ggcagatgat ggcgctcgac ttggatatgc taaagcagat cgccgctaaa
     6121 agcaattatc cggaatatgg tattagtgga cgtataaact atgtgacgga aaagggaaag
     6181 aaacagatcg gtatctctgg taataaggcg aatcatgccg acttaacggt ggaattggga
     6241 ttctcttccg acctcggtgt aacgaacgat cgtttcccgc atgaggtagg agaaggacag
     6301 ggtaatatga tgggttttgc catgaccggg gcgcaggtct ctacggaaga tatggaagat
     6361 gtggatttat acctccagac cttgggggta cccgcccgtc ggaatgtgga tgatcctacg
     6421 gttcttcaag gagagcaact tttctatcaa gcgaaatgtc atttatgcca tgtgacttcc
     6481 ttgaagacac gccctcgcgg atctgtcctt ttgaataata cggaattgcc tcaattaggt
     6541 aatcaggtga tccatcctta ttcggacttt ttattgcatg atatgggtgt tgagctaggg
     6601 gatgattatc ccagtggctt ggccaacggt aatgaatgga ggactacccc gttatgggga
     6661 ttgggattac aagaggtcgt aaacggccat acctattatt tacatgatgg ccgtgcccgg
     6721 aacctgacgg aggctattat gtggcatggt ggggaaggag ctgcgtcgcg taccctattc
     6781 tctcgcatga caaaagacga gcgggccgct ctgattaaat tcctacaaag tttataaata
     6841 aataacgcat agaatcgaaa tgaaaaaaat atataggacg ttgcttgtgg tgcttctatc
     6901 agcaggtgtt ttctccgtga aagctcaaga tacaaagaaa gagatggatg ataaatatgt
     6961 agagaacgat gtggtttcac tagcgggaaa gaagggcttt tctttttcta ccaaggccgg
     7021 tgattttttg tttaagccct atgcgttggt acaggcaagc gcttgctaca accgatatga
     7081 cgaccaaggg ctggaaagcc attatgccaa gagcgtagcg aactccggtt tcgcgatccc
     7141 taacgctatt ctcggtttta cgggtaaggc ttttggacgg gttactttca atttatcgct
     7201 gaatgccgct aagagtggag gtgctttatt gcaacaggct tggttcgacg tagcgatcaa
     7261 ggagtcgttt cgtatccgtg tcggtaagtt caagacaccg tttatgcatg gctatttaag
     7321 tactttgggg gagacgttgt ttccggtact gccttattcc gcttcccaat ccgtattgct
     7381 tccttacgac gtgaattatg tcataccgaa tatgtccacg ggattcgact tgggtgtaca
     7441 ggtacatggt ttgatccatg ataaatggaa ttatcaagtc ggtattttta atggtacggg
     7501 tatcgacgtg aatttggcga ctaagacaaa ctgcgatgat cataaatggt tgccttcgct
     7561 gttatatgcg ggtcgtctgg cctttatgcc gaagggggag atgccaacgt ctcaaggctc
     7621 accggagaat ctgaacgacg ataagatgtc tatcgccgta tctgcctctt ataatgcgga
     7681 ggccgagttc ttgaccagta gcgacacccg tgtgggcgtt gagttcgcat ggatcaagaa
     7741 ccgctggtat gtggctgccg aaggttacta tatgaatatg cattttacca agatcatgca
     7801 aaagccggat aagaatttct ggggagctta cgctcaattg ggctatttca tcactccgaa
     7861 attgcagggt gctttgcgat atgatttcta tgatcgtaac gctacggatg agggtggttt
     7921 gttgaatatg cccgccgctg gtttgaatta ttatttcttt aataataatt tgaagctaca
     7981 ggttatgtat caatatctag gtcgtagcgg tcatgctacg cagaatgacc gggatgagga
     8041 cgctattgga ttggctcgtc actccgctac ggctatgttg cagttcacgt tctaatcttt
     8101 gggtatgaaa cgatatagtc aatatataat gtatgcctta ttcctgttat tcgggctggg
     8161 ttgtgatgag ggtaagattt atccggatga gacggttgat tccgggcgaa ccgctaccgt
     8221 gtcactttct ttcactggcc tgaaagcttg gccgaaggag aatatgctct cgttatgtgc
     8281 ttttggcgag gataagtcga aacctttgca aacccagcgt atcagtaagc cggcggaaga
     8341 cggcaaaaga ctaaaactcc gattgaataa tgtcactccg gatacgagga gtatagaggt
     8401 cgctgtgatt agtaggggat tgcggttggt ttactcctat tatacgtctc cggtggatga
     8461 ttcggacgaa ccgcttgatt tgtctgtcgg cgaattggat ttagcgagct tcaaacgtat
     8521 acaagcgcag gtgttcgact tgaattgctt gtcatgtcat ggaggaggat cgggattggc
     8581 cggtcagctg gatcttaggg acgatgtggc ttataaatct ttagtgaacg taaaggcgcc
     8641 cctttcggaa gagggtaaga actacgtgac cccgggtaat ataaacaata gtttcttgct
     8701 ggatatattg gagaataatc cggtacataa ggatatgttc aatagttccg ggaaacagga
     8761 ggtccttgct ttgatccaag gttggatctt aggaggggca ttggataatt gataagaaag
     8821 aaaatgatga attatacgag gaggatagat acggataaag cggtagaaat gcaaatctct
     8881 tcattcacgg gtaaaggtgg aacaacggaa tatcaggtga tggtatctat cacggaccct
     8941 tgtttgtctt tcgtggagca attgcaaaac cttttgcggg tttatgtgac tgtcgtgaag
     9001 gaagagctat cgaatgacgc taccgccgtt ttccgccgtt attttttaag tgacgcagct
     9061 aatcagacgg atagcgtgat ggagtgggag tgcgagagcg ccttttgccc gctctctatc
     9121 gttcagcagc cgcctttgaa tggaacaaag atcgctatgt ggacctattt gcaaacgggg
     9181 atgtcggtac aaacgtacga ttccggttta ctggaagcgt cgcataacgg ttataggcac
     9241 ctctgggggg gaggtgcctt caataaggcg gccaattcgg aataccagac ccggctttta
     9301 ttgaatgact atgtgatgca attgatgggg cagcgttgta cgttggcctc tcattgtgtc
     9361 cgtacttggt tctttgtgca aaacgtagac gtgaattacg ccggtgtggt gaaagcccgg
     9421 aaagaagttt ttatcacgca gaatcttacg gagaagacgc attatattgc tagcacgggt
     9481 attgagggac gtcatgccga tccctcggtg ttggtacaga tggacagtta tgcggtggat
     9541 ggattggagc cgggacagat tcagttcctt tacgctccca cgcacttgaa tcctacttat
     9601 gaatatggag taactttcga gcggggtacg gctgttacgt atggggatcg taaacaggtc
     9661 tttatctcgg gtacggcgag tatcgataac cggggagaga ttgtctatcc gggcgatatc
     9721 gtaaaacaaa ccgagcggat gatggaaaat atcagcgtgt tgctgaaaga ggcggacgct
     9781 actactcgtg atattacgca ggcgatctcc tatttgagag atatggctga ttatgcggtg
     9841 gttaagaagt attttgaggc gcattacccg gatttgccac atttgatagt cttggccccc
     9901 gtttgccgtc ccggatggtt gatagagact gagtgtatag cggtcgtgcc gacggagtcg
     9961 tcctttaagc ctttgtgaaa taataataaa tgtacgagat atggaagaaa aaggagtata
    10021 tttggctatt caaacaccaa gacaagttag aaagaagcct atgtataaaa atggaatgta
    10081 ccgggaaacc gataaaatga gtgatctgat ctgcgagaac tatccgatgg ttttagtcat
    10141 gagccgcttt ggtatagcgc tcgggttcgg agagaagaat atcggggagg tttgccggca
    10201 gaatggggtg gatgcttgta ctttcctgac ggtcgtgaat ttcttggtcg aggaagtgaa
    10261 tacgcctgtc gagaatatca gcaaatgcct gtcgatcgag aacttgatcc gctatttgca
    10321 taatgcccat gattacttct tgaacttccg cttgccacat atccgtcgta aattggtaga
    10381 cgctatatcc gggtgcccgg aggatgtcgc ttttgtgatc acgaagtttt tcgatgagta
    10441 tgcggaggag gtaaataaac atatgtctta tgaggaacgt gctgttttcc cttatgtccg
    10501 taatttgttg gaaggaaaga gagatccgaa atacaatatt acgatcttcc gtaagcgtca
    10561 tgatcagatc gagatgaaga tcacggagtt gaaaaatatc ctgatcaaat actatccggg
    10621 agcgggtacg aatatgctga atagtgtctt gttcgatatt tttgccacgg aggaagactt
    10681 ggcttcacat acccgtgtgg aggattattt gtttgtaccg gccatattgg ctttggaaaa
    10741 acaattataa gcatgaatcg atgagtacaa atctaaagat tgcgatagcc gaaccttctg
    10801 ttatcataag gagcggactg gagaacctgt tgaaacggtt accgggtttc cgtatccaga
    10861 tggtggagat tcattcggtg gaatctcttt tcgactcgct tcgtatgcac aaaccggatg
    10921 tgttgatcgt gaatccggct ttgcccggct atttcacgtt gcaacatttg aaggaggaaa
    10981 gcggctgtgc cgagatgaaa tgtatcgctt tattatattc tgtctcagac agtgtgttat
    11041 tgcgttctta tgatgaacaa attaacatat acgatagccc tgatgagatc aagcacaaat
    11101 tggaacggtt gaacgccgag gtacttccgg atgacgagcc ggaaggggat gacgagcaac
    11161 aatcgttaag ctcgagggaa aaagagatcg tagtctgcgt cgtgaaggga atgacaaacc
    11221 gggagatagc ggatcgtttg tttctttcta cgcatacggt catcacccac cgccgtaata
    11281 tcgctcggaa acttcaaatt catagtgcca gcggtcttac gatctatgcg attgtcaata
    11341 agctggtcga attaggcgac attaaacagt aatcgtatat ttataagtaa gttaaaggga
    11401 atgtggataa gcgataaaag cgccttccgc attcccttta ctattaatat aattaaattt
    11461 aatgatcata tcttattaac gcttatcgaa aactaaaacc cgtttattcc tgtttcttct
    11521 tcaaatcatt aagcttataa gaaatgaaga aagcattttt acttggatta gcattgttat
    11581 tttccttatc tatgagcgca cagcatttcg cgttgaagaa caatcttctc tacgacgcga
    11641 ctacgactcc gaacttagga ttcgaggtgg gcttaagcaa aaaggttaca ttggatgtct
    11701 cggcgggata taatcctttc aagttcaatg acggtaagaa actgaagcat tggcttgtca
    11761 tgccggaagt gcgttattgg acttgcgaga aattcaacgg tacgtttatt ggcgtgcatg
    11821 cgttgggcgg acagtataat atcgccggga ttaaattacc ctttggcata ttccctaatt
    11881 tgaaggatca tcgttatgat ggttatttgt acggtggcgg acttacgttg ggacatcaat
    11941 ggatactgaa taagcgttgg agtatagaag ccgctatcgg cgccggttat gcccgtgtac
    12001 attatgataa gtataattgc ggggaatgtg gctccaagat cgagaccaag aactcgaact
    12061 attggggtgt aacgaaagcg gccctttcta tcatttattt tatccactaa aaaacgatct
    12121 agagagatat gagacattta ttgagtatat gtatcgcttt attgttcctc ggaggtgtga
    12181 gcctacaggc acagaacggt gtgcggggaa ctgttagttt cgagaatgta agcgcaaaga
    12241 aggacggaag ccagcttatg atgaatttta cgaccaatct gagtaatctg cgtttgaaat
    12301 cccaagagat ggtcatactg acaccggtat tgcaatcggt ggataaatcg cagtcttacc
    12361 agtttaaccc gatcgtgatt accgggcggg cacgtatgaa ggcgttgaac cgtgagttgg
    12421 gtttcgatag ttatgaattt ccccaaactc ctagcttgat tatccgtcag acgaagaagg
    12481 ggccggaatt gattccggtg gaattgtccg taccctatgc gggatggatg cgaaacgcta
    12541 ccttgatggt ggatgagaat accacgggat gcgcttcttg tgaggtctca aatgacatct
    12601 atggggtgat gagccgtgta ttgcctccgt tagcccctcc cgtttatgag cttagctatg
    12661 ttactcctcc ggtagaacct gtgaaacaac ggagcgagac gcattccgct tatttaaact
    12721 ttgaggtagg caagtccgta ttgttacgtg atttcaaaga taacgctacc gtgctgaatg
    12781 aggtgaataa gattgtaacg gaagtccgta acgataagaa tctaagcttt accgaattta
    12841 aggttaccgg atacgcttcc ccggaaggtg gctacgatta taatatgaga ttgtccgaga
    12901 gtcgtgccaa ggcttttgtc gcttacatga aagataagga gaagatggat ccttccttga
    12961 tgaaagtgaa ttggatgggt gaggattgga tcggattgcg tcaagaggtt acgaaatcag
    13021 atttggcgaa taagaaggag attctggaga tcttggatat tcaagatata aacaagcgca
    13081 aggctaaact acatgccttg aacggaggtc ggacttataa gatattattg gataaatact
    13141 atcctccttt aagacgtatt gattatacct tggcttatat cgcacgtccg ttcgacgtga
    13201 acgaggccaa gcaagtgatc aaaacgaaac ctcaatattt aagtttgaat gagatgttct
    13261 tggtagccaa ttcttatgat aaaggtagcg atcagttcaa ggaggtattc gatatcgccg
    13321 ttcgtcttta tccgaccgac ccgatcgctc aattaaatac ggcggccctt gagattgaga
    13381 ctggtgctta cgatccggcc atcagtcgtt tgcaaggtat taatttgccg gaagcatgga
    13441 ataacctagg tgtcgcttat gcgatgaaga aggattatac gaccgctatg caatatttcg
    13501 atcaagctgc ccaagccggc atgcaggatg ccgccgcgaa ccgggatgag ctggccgctt
    13561 ggttggccga gcaataatgg agatacttac cttcgaatat aaaaaaagcc cccgtttccg
    13621 gaggcttttt ttgtgcttat aatttagctt tccattcatt catcaactcg gtaatggttt
    13681 cccgtaccga agtgatctta ttcgctcgcc aagcgttact gccggcgaaa gcgtatccat
    13741 tctcgaaatt ccctttgaag gcgttgtaca aggcggtgac gatacaatac gggctgcgtg
    13801 atatatcgca cgtcttgata cagttgaagg gacaagcttt cggttgcttg attcccgcct
    13861 tcactttctc aaggaaactg caatggatgg ctcgtccggg catgccgacg ggacttttga
    13921 tgatctctat gtccttctcc tctgcctgta tataggtctg tttgaaggct tccgaggcat
    13981 cgcattccgt ggtggtaacg aaccgggttc ctaactgaac gcctgatgct ccaaggtcta
    14041 tcatgcgttt gatatcttca cccgtataaa tgcctcctgc cgcaattacc gggatctttt
    14101 tgtcgtattt ctgctcgaaa tgagagactt cctctacgac ttgaggtaat aattcttcca
    14161 atgagaaatg ctggtcttcc aactggtttt ccttatatcc cagatgtcca cccgctttcg
    14221 ggccttctag taccaccgca tccggaagat aatcatagtt attcttccat ttctcgcaga
    14281 tgatgcgtac ggcacgtgcg ctggaaacga tgggaaccag cttggtgacg ctatctttct
    14341 tgaggaaaga aggcaagtcc aaaggcagtc cggcaccgct gaaaatgatg tctacctttt
    14401 ccgctatact ggttttcacc aattcggcga agtcggaaag agccaccatt acgtttacgc
    14461 cgatgatacc tttcgctttt tcccgggcct tgcggatctc ttccgctaac ccgagattcc
    14521 cagcttccgt ataattgctg ggtgacaatt tcttatataa aagtccgaga ccggctgcgg
    14581 agataacgcc gatcccacct tcatttgcaa cggccgaggc taagccggaa agagagatgc
    14641 ctacgcccat tccaccttgg atgattggaa tacgagcctt taggtctccg attgttaatg
    14701 tcttcattaa aaaaataaat atagtgtttc aataatcgag gcaaaggtag cacaatatcc
    14761 caataaatgt gcgaaatgga ccagaattat cgcgcaaata ttctagtcat gtgcaatgta
    14821 tggaacgaac cgattatttt atgtaaattc gtccctgaat aattaggcaa gacgtctgta
    14881 acaggattgt aatgtatgtg aaacgggtgt gaaacaggag cgttgtaact ttgcgacgca
    14941 aatatagttt ttatagttag gaatgaaatt aggaaaagtt atagcgctca tgttagtgct
    15001 gcttccattc agtatgggag cgcaggaggt ggatcagtcg gtggaaaaac atatcgattc
    15061 cttggctacg gaagtgacta ccttggataa ggtagtccag aagctaagca aattcaaggt
    15121 ttccgcttat atccaaggac aataccaata tggacaggag gacgctacct tgaaagtggg
    15181 cgataagaac gagaacttgg ataaagggtt taaccggatc ggtatccgcc gggggcgtat
    15241 gaagtttgag tacaatgatg ggatcggaac aggtgctgtc cagatcgagg tgaatgataa
    15301 gggagtaagt ttccgtgatc tgtatatcgg tatcaaggac ccttggacga agcgtagcca
    15361 gttgatggct ggtgtgttca accgtccttt cggttatgag gtctgttatt ccacgagttc
    15421 tctcgaatct ccggagagag cgactattat ccagtatttc ttcccggatg agcgtgactt
    15481 gggagcgatg cttaccttac gtaccaagac taccagccca ttgagtttct tgcgattgga
    15541 tgccggtctg tttgccggaa acagtattaa ccgggagacg gatagccgga aagatttcat
    15601 cgggcgtctg ggtgccgaga aggcgatagg cgactgggga aaatggggag ccggtttctc
    15661 ctattaccat ggttttgtct acaacccgac taccgaggcg tatgagatgc gtggcaatca
    15721 tttcgttaag agggatatgg gagagacggg tacttatatg aagcgccagt atttaggttt
    15781 ggatggacag tttagttttc tttcatcttt aggaaagacc actctccgtg cggaaggttt
    15841 aatcggtacc caacccggta tcgccgggag cagtaaaagc ccgaactaca gtacccgacc
    15901 ggagaatttg ccggaaaatt ctttgttcaa gcgtcctttc cttggttact tcttttattt
    15961 ggtacaggat ataggcgcct ctcctttctc cgccgtattg aaatatgacg tttacgatcc
    16021 gaatacgaag gtgagtggaa atgaggttgg ggcggaaaat agtttcacct caaaaaccga
    16081 tttggctcaa agcacgatag gtatcggcgg tatctataat ttcaataaac atatccgtct
    16141 acaagcttac tacgagttta acttcaatga gaaaagtaat ctcgtgaagg gctacgagaa
    16201 cgaccggaag gataatgtat tgacagttcg tcttcaatat aagttttaat tcataggatt
    16261 gtaatatctg tttcatccca ttgaaatacc gaagtattta ttttgtatcg taaataaaag
    16321 ataaatacaa aataatgaag aagacgattt tattagctgc catggcagcg tgtttgtttg
    16381 ctacgaatgt gtttgcccag aagataaagg gtagcgatac ttgtttgcct cttacccaga
    16441 ctgaagccga gaatttcatg aataagaaca aagccgctaa gataacggtg acgggtggtg
    16501 gctccggcgt ggggatctcc gctttgatgg aaggcactac ggatatagcg atggcttccc
    16561 gtaagatgaa attcgacgag cgcatgaagt tgcaagaagc cggaaagaaa acgaaagagg
    16621 aggtgatcgc ctacgacgct ctggctgttg tcgtgcatcc ttccaacaag gtatccaatc
    16681 tgacccggga gcaattggaa ggcattttta ccggcaagat taagaattgg aaagaagtgg
    16741 gtggtgcgga tatgaagatc gtggcctatt cccgcgagac ttcttccgga acctacgagt
    16801 tcttcaagga gagcgtgttg aaaaataaga actatatgaa cggtatcttg agcatgccgg
    16861 ctacaggtgc cattatacaa agcgtaagcc agacgaaagg agccattggc tatgtaggtc
    16921 ttgcttattt gaataaagaa gtgaagccga tccatgtatc gtatgatgcc ggaaaatcct
    16981 acgtggagcc ttcgttggag aacgcgagga ataagaccta tccggttgtc cgtccgttgt
    17041 tctattacta tgagacgaag aatgcctcaa aggtgcgacc gttcatcgat tatgtgatgt
    17101 ctgccgaagg acaagcgacg gtgaagaagg ttggttatat cccggtaaag taagcggaga
    17161 atccggacag cgttgtatga gcacatcata caacgctgtc taaggtgctt cgacagtact
    17221 gtctaaggtg ttaagacaac gctgtcttat gtgttgggat aagattgtcc gtccgtctct
    17281 tccagaaact gatccatata cagattctcg ccatcccata cgatataaga gaagaattgc
    17341 atccaatccc cggctatgag aatacgggag gtacggctta acatcaagtc caacatgatg
    17401 tggcgatggc cgaaaatgaa gaagtttata tcgggatgcg tctttagata ttccttggcg
    17461 aaaacaacca tatattctgc gtcttcccct tgatactttt tagcctcttg cttttccagt
    17521 ccgctcttcc ggctgttgag cgaccagcct aaagcgaacc cgaacgtcca gcggggatgt
    17581 attcccgcat ataaccattg gcagaacttg ttccggaaaa tagccctgat cagacggaat
    17641 gccttactcc ggaaatctac ctcatcgcca tgcccgagga agaaacgttt ccccaataaa
    17701 tcgactgtca aggtatcccg atggatgatg gcgcctatct ctttcggcaa gtagtcgaac
    17761 atccagatgt catggttacc gataaagata tgtatttcta tacctctgtc cgctaactcg
    17821 gccaatttcc ccagaaaacg tacatggcct ttcggcacga cgtatttgta ttcgtaccaa
    17881 tagtcgaata gatctcccag aaaccaaatg gcggaagcgt cttccttgat gctatccagc
    17941 caacgtacca gtttcttctc gatggctaaa gggtccttgt ggaaacgggc tcccagatgt
    18001 gcgtctgagg cgaaatatat tttcatagaa aacctaattc cagtttagcc tcctccgtca
    18061 tcatgtcctt gtcccattcc ggctcgaaga cgaggtttac ctctacattg ttcaccccat
    18121 cgaccgcttc taccttcata cggacatctt ccaatatgaa atcggccgcc ggacagttcg
    18181 gggcggtgag ggtcatatcg atgcgtacat ttttttcctc atcgatatct accttatata
    18241 taagcccaag atcgtatacg tttacgggta tttccgggtc gtataccgtc ttcagcatag
    18301 cgacgatcgc ttcttctgtt tggagaaatt cgttgttcat cttcttttgt tttatacgcg
    18361 aatatacatt aatacttcta tatactaaac cgggggaaaa gagaatttgt ttcaccggat
    18421 cagccttcct tcgtctgcat agctataata gccgctatcg gacaggatga tatggtccag
    18481 tatcctaata tccatcagct tcgccgcctt ttggatacgc tcggtcaagg catcgtcgtg
    18541 cgtactgggg cggaggctac cggatggatg attatggcat aggattatac cggaggccaa
    18601 ggcgttgatc gccgctttta ataccaaacg gatatccacg gaagtctggt ttactccgcc
    18661 ctgactgatt tttacctttt gtatcacctt atttaatgga ttggttagag cgatccagag
    18721 ttcctcataa ggtaaatcgc atagttgggt acggaatagg agataggagt ctttgctgct
    18781 tcggatagca tcttgaggag acgcctctga ggtttcccgc cgtttcccta gttccatagc
    18841 ggcgcagatc gtgaccgcct tcgcctctcc gataccttta aagccggaag ttaattcttt
    18901 gatggaacgt ttacccaatg tattcagatt gttgtttacg gagtgaagta tccgttgaga
    18961 gagttgtacg gccgtctcct cattgttgcc ggatccgatc agtatggcga tcaattcggc
    19021 atcgcttaat acggaagcgc ctttttgaag cattttctca cggggcctgt cttcttcggc
    19081 ccattccttg atggaaagtt ttcctgtctt ttctttcata gtcgggaaag gtttatgatt
    19141 tggttaaaaa aatagttccc gcctgcttat caagcgggaa ccgtatattt tgacaagacc
    19201 cggattactc gcggatacgg cctacgtaag aaccatcagt cgtattgatc tcgataacct
    19261 cgccctcgtt gatgaacaac ggaacgcgaa cttccgcacc agtctctacg gttgccggtt
    19321 tcaaggtgtt agtagcagtg tcacctttaa tacccggttc tgtataagta acttttaatt
    19381 gaacttttgt aggcatgtcg gcgaaaagaa ccgtatcggt agatgcatca gaaacaacgt
    19441 ctacaatttc tccctctttc atgaaatcaa cgccgttgat caagtttttg tcgatgatca
    19501 cgtcatcgaa tgtctcttgg ttcatgaaat gataatgctc gccttccgta taagtgaact
    19561 gatacgggcg acgttctacg cgtacatctt ccaacttctc accgatattg aaacgacgct
    19621 cgatctgacc gccttttaca acatctttca atgtggtacg catgatggta ttacctttac
    19681 ccggttttac gtgaaggaaa tcgacgcaga aatagagttt tccgtccaaa cggatacaag
    19741 ttcctttctt aatgtcttgt gaattgatca tatttatttt ctttatttat aatgttatag
    19801 agtaatcctt aacgattttc gggggcaaaa gtagtacatt cctgctaaag tagcaaaaag
    19861 ttttgcgtat ttatatggaa aaatagttgc aaatcaaccg aataaccgga accaagaccg
    19921 ctgtcatgat acccatcaag ccaatcgcca gtccgcttaa tgctccttcg atggccccga
    19981 tttgaatggc cgctgctgtt cctactccat gggaggaagc ccctaacgcc agtcctttag
    20041 cgatatggct atctattccc agtaccctca tcacgatagg gcccactata ctgccaaaga
    20101 ttcctaccgc tacgacgatg acggcggtaa gtgaaggtat gccgcccgct ttctccgcta
    20161 tccccatagc gatcggggtg gtgacggatt tcggttggag cgtggcgatc aacgcttggt
    20221 cggctcccat caatttaccg atgatgatta cgcttacgat tccgacaatg gccccgacaa
    20281 atacggaagt caagatcgaa acgacatttc cctttagata ttggatttgc tcatataaca
    20341 catagccaag ggccactacg gaaggcccca gcataaaatg gatcaaatga ctgctttgct
    20401 ggaacgactc atattgaatg cctaggactt ccagtaccac gataatcacg aagatggtcg
    20461 taagcaaagg atgcaaaaga ctgatatgga ctttcttgta aagagccaag gaagtcaggt
    20521 aggtaccaat taccaaggta agagcgaaaa tctcggaatg cgccagatta tccatggtct
    20581 atttcccctt ttccagtttt tgttgcacca acgctacgct ggcgatgact aaaattgtac
    20641 ttactacgga agcgatcagc aggactgccc aatactcgga gatgatcccg aaggaattca
    20701 taagccctac accagctgga acgaagaata atcccatgtt ttgggtaaga accgtggaaa
    20761 gacgtttcac cttttcaggt tttactttct tgaacgcgag ggctaaaaat aatagcacca
    20821 tcccaattac gctacccggt atgaaaccgt cgataaagta gctgataaac tctcccgtga
    20881 aatagaagaa gagaatgtaa aatgcttctg ttagcatagt ttttctacct tttttgataa
    20941 ccgctacaaa gataacagct atttcgtaga tatgttctat aacatattat tttaacattg
    21001 tagggacggc gtccgtcccc ccgtggtatc aagctaacgc ggaagtaatg aacatataaa
    21061 tcatcatacc gataatatcg ttggtaatgg tgataaacgg cccggtcgcc aaggccggat
    21121 ctatcttcat cttatctaag gtcatgggaa ctaacgtgcc gaatatactg gcgaacatta
    21181 cgacggcgaa taggcttaaa gatacggagg ccgtaatccc ccggtctccc agcatgaaga
    21241 agttgtaaat gaacacgacc agactgataa tgctggcatt gattaacgaa actacggact
    21301 cttttaggat ttgcggtacg atattccctt ccttcaaggt attgtttgcc aagccttgta
    21361 ccacgatagc ggaagattgt atgcctacgt ttccaccggt accaccgatc agcgggataa
    21421 atagcgccat cttcgggtta gtggcgaaac tgctctcgaa accaccgagg ataacggagt
    21481 ttcccaatcc tccgatcatg ccgatcagca gccaaggtag gcgggcggcg gtttgggtga
    21541 atacattatc cgaggtttcc acgtcttgcg agataccgga tgccaactgg taatcacgct
    21601 cgtgttgctc gcgtacctca tccataacgt catcgatcgt gatacgtcct accagacgtc
    21661 cgatactatc gactacgggc aaggctacca agtcgtattt ctcgatcgtc tccgtaacct
    21721 cctcgatact gtcgctgtcg cgaacggaga tcgggtcttt tttcatgaca tgcttgatct
    21781 tggagacgga tgggtgggta atcagtttct gcaaggggag cacgcctttc aagcgctcgt
    21841 cgtcgtccac tacatataca taatagatct cgctcatctc ctccgcttgc ttgcgcatct
    21901 cgtcgataca tttgggcata ctccaattct cgttcaccac gatcatctcg gtacccatca
    21961 aaccgccggc ggtgtcctcg tcgtatttca acaagtccac gatatcaccg gcctgttcta
    22021 cgtcctcgat atgcgaaagg atctcctctt gggtatcctc gtccaactca cgcatcaagt
    22081 caacggcatc atccgtttcc atgttatcga cgaaacgctt ggcgataagc tcattgggaa
    22141 gttccttcaa taacttatga cggtcttcct catccaactc catcaataca tccgccgctt
    22201 tgtcgccatc catcaataga tagagataaa tggcctcttg caagttcagt tcttgataaa
    22261 gctcggctat atcggcagga tacagttcat gaagtacctc ctgtgccttc gcgtcatctt
    22321 tggcctcgat gatgcttttc aggttctcga tgtaatcttt cgtcagttcg atcattggac
    22381 tcttatatta ttataggaca tcaccagcct gcttctccag atgcttttgg ctgatcaagg
    22441 tcagttccac gaattgctcc acggataact gttccgggcg cttgtcgaat atcggcaagg
    22501 cgtaatccgg gcaatcttta cccaataggg gtttcatgga attacgaagc gtttttcttc
    22561 gttggttgaa tgaggtcttt actacggtct tgaataactt ctcgtcgcat cccagctcct
    22621 tgcggtcgtt acgagtcatt ttcaatacgg cgcttttcac ctttggaggc ggatcgaata
    22681 ctttctcact gacagtaaag aggtattcca cgtcgtacca agcttgaagc aatacgctca
    22741 agattccgta cgtcttgcta ccgggacctg ccgctaggcg ttccgctacc tctttttgta
    22801 acatccccga gcagcaggga atctggtcct tataatcgag gactttgaag aatatctggc
    22861 tggagatatt atagggataa ttaccgatca cacaaaactg ccccggaaat agcttcgaga
    22921 gatccaattt caggaaatcc tcggcgatga tacgtccttt cagatcgggg aaattctggt
    22981 tcaggtaatc tacggattcc atgtccaact cgacaacggt caaatcatgt cccgcctcca
    23041 gcaagaactg ggtaaggact cccattcccg gtccgatttc caagaccggc aaggatttga
    23101 aagtatcgag tgtgtccgca atgcgctgtg ctatttgcag atcctttagg aaatgttgcc
    23161 ctaatgcttt ttttggctta actaatctca tccacttttc ggtgtaatgt gtttgttttt
    23221 aaatattatg cttatctttg cggatgcaca aaagtacaat aaataattta aagttcccta
    23281 tacctaatgg attttaagag cattctacgt acgtttctga agataattct acctttagcc
    23341 ttcggctgtt tactcctttg gtttttgtat cggaaaatgg atatcactga gatttggcga
    23401 gtagtcaagg agggggttcg ttatgatatt attctggttt ctttactgtt cggcttgttc
    23461 gccaatatcg tccgtggttt acggtgggga ttgctgatca gttccttggg cgagcgtttc
    23521 aagatgagta acgtgattta cgccgtgttg ggtaattacg cggtgaatct ggtattgccc
    23581 cgtgtcggcg aggtatggcg ttgcggcatg atcacgaaat acgataagat ctcgtttacc
    23641 aagcttttag gtaccttgtt gatcgaccgt gtgagcgata cgatcatggt cggtttgata
    23701 accttgatga tattcatatt taatataagc ttctttacga gtttcttcgc taagaacccg
    23761 gctttgctcg aagggttcca atccatgttt aattcgatat ggatttacgt ggcggtgata
    23821 atttttgtcg ctgtaatttg gtttgtattc acttatatga gtaactttac gctggtacag
    23881 aaagccaaag gcatgttgaa gaatatatgg accggtatga agagtatctg gtacatggag
    23941 cataagatgc gtttcgtgat agagacgtta ttgatttggg gaggttattt ctgttacttt
    24001 tatataacgt tctatgcttt cgactttacc aaggacttgg gtatcgtggt cgggctgatc
    24061 acgtttacga tgagtagtat cggcgtggcg gtgcctgttc aaggcggtat cggaccgtgg
    24121 catttcatgg tgatcgctac cttggtttgt tttggcgtga acgagaatga tgcggcggcg
    24181 ttcgccttgg tcgttcatac ggtacagacg gtatggactg gattgtgcgg attattcggc
    24241 gtggtggctt tgccgctcac caaccgggag aacaaagagg ctccggtcgc tgtttcgtga
    24301 tgaatacaag atatgtatta aatatgaact gaactaaatt attaacatct atgtcagcag
    24361 aaatcaaaga tctatctccg aagcatgtat ggggttattt ttatgacctt acgcaaatcc
    24421 cccgtccgac cggacatatg gaggcagtaa cccgttttat gatatccttt ggtaaaggat
    24481 tgggactgga aaccctgcaa gatgaggtgg gtaacgtatt gatccgtaag ccggccacgc
    24541 ccggaatgga aggtcgtaag accgtgacat tgcagtctca tctggatatg gttccccaaa
    24601 aaaactcttc cgtaaagcat gatttcgaga aagatccgat cgacgcttac atagacggtg
    24661 attgggtgac ggcccgtgag acgactttgg gggcggacaa tggcatgggc gccgctctgg
    24721 cgatggccgt gttggcggac aatagcttgc gtcacggacc gatcgaggcc ctgtttacga
    24781 ttgatgagga acagggaatg gacggcgctt tcggcttgaa gccgcatttc ttacagggtg
    24841 atattttatt gaattgtgat tccgagaagg aaggggagtt gttcgtaggt tgcgcgggtg
    24901 gcgctaacgt gaatgtctct ttccaattta aggaggatac ttatattccg gaaggtgacg
    24961 tggctgtcaa ggttagcttg tctggcttga aaggtggcca ttccggtgtg gatattcatt
    25021 tagggcgtgc gaatgcgaat aagttgatct tccgtttctt gaaagaggcg gtttgtgatt
    25081 atggcgctcg cttgtcctct gtggcgggtg gttccttgcc taacgctatc cctcgtgagg
    25141 cttttgccgt gataacgatt ccgggtgata acgtggagtc tctttgggag ctagtggctg
    25201 attaccaaga tatgttccgt acggagtata tgggtgtgga ggatcagatc gatttcgtcg
    25261 cggagatggt tgaattgccg tctacgttga ttccggagga gatacaggat gatttgatca
    25321 atgcgatcga gggttgccag aatggtgtga ttagcatgtt gcatgatttc ccgggtacgg
    25381 ttgagtcttc ctctaacttg gcgatcgtga agacatctga tgagttgatc gaggtgaaga
    25441 tcttggtgcg tagctcatcc gagtctcgca gggattctgt ttgctcaagt ctggaaagtg
    25501 tattcgcttt ggcaggggct aaggtggagg agtccggtca ttataatggc tggcagccta
    25561 atatcaattc cccgatcttg aacttgatga aatctaccta tctggattta tttggtaagg
    25621 aacctgaggt gaaggtgatg catgccggat tggaatgcgg tatcatccaa gg
//
LOCUS       DBMDTB010000058        25336 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_690_length_25336_cov_11.489281, whole genome shotgun sequence.
ACCESSION   DBMDTB010000058 DBMDTB010000000
VERSION     DBMDTB010000058.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 25336)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 25336)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25336
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_690_length_25336_cov_11.489281"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..594
                     /locus_tag="ACZPB4_10425"
     CDS             <1..594
                     /locus_tag="ACZPB4_10425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HIR1098660.1"
                     /translation="NTLGEFLANVGKTQLHIAETEKYAHVTFFFNGGRETPFDSEERI
                     LVPSPKVATYDLKPEMSAFEVKDKLVDAINTKKFDFIVVNYANGDMVGHTGIYKAIEK
                     AVVTIDACLHDTVEAAKANDYEVIIIADHGNADHALNEDGTPNTAHSLNPVPFVYVTA
                     NKDAKVEDGILADVAPSILHILGLKQPKEMTGKSLIK"
     gene            611..1192
                     /locus_tag="ACZPB4_10430"
     CDS             611..1192
                     /locus_tag="ACZPB4_10430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3109 family protein"
                     /protein_id="HIR1098661.1"
                     /translation="MIQIDDTLVSLDVIERYFLCDLSKCKGECCVEGDSGAPLEDSEL
                     AKLQKVLPIIWDDLSPKAQEVINKQGVAYIDEEGDTVTSIVNGKDCVFTCYDADGTCK
                     CAIEKAYREGKTDFYKPVSCHLYPIRVTQYRDFKAVNYHRWSVCKAAEILGKKEQLPV
                     YKFLKEPLIRKFGQAWYKALEECAEEWKKQREE"
     gene            complement(1286..2198)
                     /locus_tag="ACZPB4_10435"
                     /pseudo
     CDS             complement(1286..2198)
                     /locus_tag="ACZPB4_10435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966924.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
     gene            3621..6896
                     /locus_tag="ACZPB4_10440"
     CDS             3621..6896
                     /locus_tag="ACZPB4_10440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6383 domain-containing protein"
                     /protein_id="HIR1098662.1"
                     /translation="MNKKFSTLLAGAALLGAVTANGAVKLNQGANNGLYQLKAGSAFL
                     SITENSTTHEDEIKMVSHSSANLGGTMWCVTVDAENQGQNPKYDFTNKIGKFLGLEIS
                     TIKGKAAAPLAAVPAVVGGDLSGWKFSPVFKNGVEKSVLYSYFTNDSVIGLKVNTSGD
                     VEMVKTIATTAGITAAGFTEFELVEAASIVVSGADELNTIFGTQDKKAGITLKFTPDV
                     LGDGAVNYFTEKKFTVEASGTANYFHVLRADSSYLYVDTAYTNAVGGAKFLAYNWSNL
                     KDTYKTGTKNHATPKDSINATDLSDQYKFMFTYWPSNDSLEIQVKQSLLKTSETYWKD
                     VTATTAMQNQHISLQELLKDKVRILTVDAAQNTKIELGFAGCKVLPTTKTTVDDGVYV
                     IRNAKTGKYYAAPLYNESASSKYEWVTLDIQDAAHMPAYQWVVLKKNVTDKNKVSAVD
                     LYNREYNDGTAADATLQLNKNAGATYMYAASFGDSLEFIPVAKEIYTDKYVGYKHLTN
                     DELITNKYTFNYWHPYASDKFIGVKDSTMNVLEGKKAFTLKSSYKEHAYGYNPSEEVS
                     GNADKKITGRIPGLVRPVRTMYIITNGETTFRNHNVAVESKYKLSKYYPNTTNDSVYF
                     KENNHIEGNHYYAILEATSAGAISTHKAGVSDYDASATLKAQVMGETRTSAFAIAPDE
                     TPLYRQFNNELLGENVDNSADSLMFKETIRGEYLMDEHNGALLNKDVDYAGIWSEGKA
                     DGKLAFRIDTAWLTRGAGKVKPQYLVSAYRELIEGEKIIPCTETGKHITADGQVTEDP
                     YQCVHAVHVKTPAFIYGKYLVNYSDSAAAVAARKEALNPYLFNTKAVSNSSYTRVGFV
                     PAVQYGDTLIVLTGKYKAMTADQLKNEGIESIMAVYKKDYPKFINVLSGDKHKNVTWS
                     FRYVNPDKAALAYVDGKEGENNSFLIESNVYATGTDGDNQYQTIKGDLAKAIAPNEAA
                     AWLKMHNGCLVLTDASSTFGAAKTGGDGALVFNAYSKTEDDDMVTSNDNINNVEGVSV
                     IAGNGTVTIQGAAGKSVVITNILGKVVAETVLTSDNATIAVPAGIVAVAVDGEEAVKV
                     VVK"
     gene            complement(7114..7434)
                     /locus_tag="ACZPB4_10445"
     CDS             complement(7114..7434)
                     /locus_tag="ACZPB4_10445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0031240 - external side of cell outer
                     membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="T9SS type A sorting domain-containing protein"
                     /protein_id="HIR1098663.1"
                     /translation="MKLIHIIALALAFSASYPVYAQANKSGVKTFASRQEDPSPIEIT
                     AYENRIKVENAPVGSILEIYSVVGIKVKEIEVKQSTAEYVVDIAKGYYIIRIGDTVRK
                     VAIR"
     gene            complement(7521..8435)
                     /locus_tag="ACZPB4_10450"
     CDS             complement(7521..8435)
                     /locus_tag="ACZPB4_10450"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016891 - RNA endonuclease activity
                     producing 5'-phosphomonoesters, hydrolytic mechanism
                     [Evidence IEA];
                     GO_process: GO:0042780 - tRNA 3'-end processing [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HIR1098664.1"
                     /translation="MADFDINILGCGSALPTTRHLATSQIVDLRDKLYMIDCGEGTQV
                     QMRRMRIKFSRLNHIFISHLHGDHCFGLPGLISTLGMLGRNGELVIHGPKEIESYMRP
                     VLDIFCKGLPYEIRFNLIDPTTHSLVMEDRSLSVYSIPLKHRIPCCGYLFAEKAKEAH
                     IIREMTDFYQVPVRMMQEIKRGADFVTPEGEVIPNARLTRPAVAPKRYAYCSDTAFHP
                     SIIPIIEGVDLLYHEATFAECDAARAKETFHSTARQAAEIAYKAQVKRLVIGHYSARY
                     EDMAPLKKEADKIFPGTILGEEGMRLSV"
     gene            8760..10355
                     /locus_tag="ACZPB4_10455"
     CDS             8760..10355
                     /locus_tag="ACZPB4_10455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M28 family peptidase"
                     /protein_id="HIR1098665.1"
                     /translation="MNKNFISVFLLMLAMGVSVMAQSYEEDLAFFKERVKTLGSDEFG
                     GRKPLTEYETKTIHYIADEFKKLGLQPANGDSYFQPVKEISTFTRPVKNKITVKCAKG
                     SMDLKFSDDIVVWTNRGTEKVVIPTTDYVFCGFGINAPEYGWNDYANVDVKGKIVIAM
                     VNDPGFYDASLFRGKNMTYYGRWTYKFEEAQRQGAAGLLVLHNEAAASYGWKVCQASH
                     VQTNIALCSETMNAEALGMKGWLSEEACKKMFALSGLNFDETIAAAKKPGFKSFTMKA
                     KSKVILNVKMTVGESHNVAAVLPGTDLKDEYLVFTAHWDHFGIGTPIDGDSIYNGASD
                     NASGVATLMLLAKKYQSLPVHPRRSIVFVAVTSEECGLLGSQYYCEHPLFPLSKTAIN
                     LNFDGTAPRERTHDISLRAAGKTDTDALVIAMASAQGRTVKVITEDPAGGYFRSDHFN
                     FVKKGVPTILVGGGKDYVDKARHEAKPKVYRYHQPNDEYDESWWDFDGAMEDMNLMFS
                     IGLVIANNDEMPKWTKEADFQRQ"
     gene            complement(10478..11629)
                     /locus_tag="ACZPB4_10460"
     CDS             complement(10478..11629)
                     /locus_tag="ACZPB4_10460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome d ubiquinol oxidase subunit II"
                     /protein_id="HIR1098666.1"
                     /translation="MDSTYILLQHYWWFLVSLLGALLVFLLFVQGGQSLLFTIGKTEI
                     QQKMLLNSTGRKWEFTFTTLVTFGGAFFASFPLFYSTSFGGAYWVWMLILLCFVIQAV
                     SYEYQAKKGNLLGKKTYQVFLMINGIAGPILLGTAVATFFNGAEFIVNKEQLTDVAMP
                     VISTWANPWHGLEAALVFWNLCLGLAVFFLARALALLYFINNIDDPEIVAKSRKQLIP
                     ETILFLVFFLTFLIRLLLVDGFAVNPDTGEVFMQPYKYFMNLIEMPIVLAVLLIGVVG
                     VLFGIGKTIFSKTWRKGIWFAGAGTVLTVLALLLCAGWNNTAYYPSLADLQSSLTIQN
                     SCSSPFTLKVMSYVSILVPFVLAYIFYAWRALDLHKINSKEMQEGGHTY"
     gene            complement(11670..13226)
                     /locus_tag="ACZPB4_10465"
     CDS             complement(11670..13226)
                     /locus_tag="ACZPB4_10465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0070069 - cytochrome complex [Evidence
                     IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0019646 - aerobic electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome ubiquinol oxidase subunit I"
                     /protein_id="HIR1098667.1"
                     /translation="MIENIDTSLIDWSRAQFALTAMYHWLFVPLTLGLGVIQAIMETI
                     YYRTGNEAWKKTAQFWMKLFGINFAIGVATGLILEFEFGTNWSNYSWFVGDIFGAPLA
                     IEGILAFFMEATFIAVMFFGWDKVSKRFHLASTWLTIIGATLSALWILIANAWMQYPV
                     GMHFNPDTVRNEMFDFWAVALSPVAINKFFHTVLSGWIVGALFVLGISCWYLLKKRNT
                     EFALSSIKVSAIFGLVASILIIWTGDGSAYQVAQKQPMKLAAMEGLYEGGNGVGLVGI
                     GILNPAKTSYLDNQNAFIFDIKFPKLLSFLAERDMNAYVPGIVNLIEGGYTTNKGTVA
                     LSAKEKIEKGKTAIKALADYRKAVKDKDTAAAAQYRVTLEENFPYFGYGYIKDPAELI
                     PHVGLTFYSFRVMVILGCFFILLFIITLIWDKKGKIANTRWLQYVGLWSIPLGYIAGQ
                     AGWIVAEVGRQPWAIQDILPTSASISKLNPSSVQTTFYLFLILFTILLIAEIGIMVKA
                     IKKGPEAAAH"
     gene            complement(13240..13467)
                     /locus_tag="ACZPB4_10470"
     CDS             complement(13240..13467)
                     /locus_tag="ACZPB4_10470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4492 domain-containing protein"
                     /protein_id="HIR1098668.1"
                     /translation="MKKESAFIRIYRFYLEGFREMKLGKTLWLIILVKLFIMFFILRL
                     FFFPNYLGQFDSDSEKENHVSNELIQRAINP"
     gene            13759..15249
                     /locus_tag="ACZPB4_10475"
     CDS             13759..15249
                     /locus_tag="ACZPB4_10475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009040855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HIR1098669.1"
                     /translation="MSNISRRSFLQKGTAAAAALTIVPSAVLGKTHGHIAPTDKLNIA
                     GVGIGGMGNANLKNMETTENIVALCDIDWKYSKPVFDRHPQAKKYWDYRKMYDEMGKS
                     IDAVLVATADHTHAMITADAMTLGKHVYTQKPLTHSVYESRLLTNLAKKYDVATQMGN
                     QGSSLAEGVDLICEWIWNGEIGEVTKVECATNRPIWPQGLNAPEKVDKIPSTLNWDLF
                     TGPAKLRPFNKTYHPWNWRGWWDYGTGALGDMACHILHPVFKGLNLGYPTRVQGSSTL
                     LLQDCAPNAQHVKLVFPARDNMPKVAMPEVEVHWYDGGMMPDRPEGFPQGKELMGEGG
                     GLCIFHGTKDTLICGCYGVNPWLLSGRKPNVPQTLRRVKDAMKGGHEQDWIRACKESA
                     GSRVQTKSNFLEAGPFNEMVVMGVLAVRLQRLNKELLWDGPNMRFTNIDPNETIKIIK
                     KDTFEVIDGDPKFKTEWTDPINAQEFAAGLIKHNYREGWKLVDMPR"
     gene            15272..16126
                     /locus_tag="ACZPB4_10480"
     CDS             15272..16126
                     /locus_tag="ACZPB4_10480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-disaccharide hydrolase"
                     /protein_id="HIR1098670.1"
                     /translation="MKKSVLLASAAIMMCYFTSCGGGKKTEEAPAAAETTTEAATPEY
                     KLMTDLPTVDITTFPKDKEGRYVIFDGKTFNGWRGYDRADVPGAWTIEDGAIKINGSG
                     AGEAGASNGGDLIFAHKLGNFELEFEWKVGKGSNSGVFIMIQEVEGQPSYISAPEYQV
                     LDNENHPDAKLGKDGNRKSSSLYDMIPAKPQNAKPFGEWNKGKIMCYKGTVVHYLNSD
                     EPVVEYHLWTPQWKEMLDNSKFSKDKWPLAYELLLNCGGANKEGFIGFQDHGDDVWFR
                     NITVKVLD"
     gene            16244..16750
                     /locus_tag="ACZPB4_10485"
     CDS             16244..16750
                     /locus_tag="ACZPB4_10485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DoxX family membrane protein"
                     /protein_id="HIR1098671.1"
                     /translation="MKIEQGYTKAQMTWLMMLRLFIGWHFMYEGLVKIMNPKWTSLPY
                     LLDSKGPAASFFIKLTQDDSLMTTINFLNEWALLLIGLGLTLGCLYRLSSVGGMILLA
                     MYTLSHPSFVGASYMMPFEGSYLWIDKNLVEFAALGLMCVFPTSQIIGFDRVLGRVCP
                     ILHKLKFI"
     gene            16756..18414
                     /locus_tag="ACZPB4_10490"
     CDS             16756..18414
                     /locus_tag="ACZPB4_10490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family protein"
                     /protein_id="HIR1098672.1"
                     /translation="MATEDAKNTPSQEQMPDKGRRDTLKTLATVPILGALAYGVYQKR
                     KDALRGRNISDVFQVSNRQASYLEPQGDGKKIRIGLVGFGIRGKQLMRAAGFAEPSWI
                     DKMKEANKLNKKDTRYQQYMEQDDLNIEITAVCDIFDVYGEAAVLTGSNIHREGSGGK
                     FGPAPKRYRTYQELVTAPDVDAVIIAGPDHWHSTIAMAAARAGKHVYCEKPLSWTVPE
                     TYMVRQVIKETGVVFQLGHQGRQTDCYQKAEEIIGNGLLGPVNLIEVCTNRNSPNGAW
                     VYDIIEGSNPNTIDWKQFEGDPERIKEYMDYMTSNKLERYIGPDERSKFSLERFFRWR
                     CWWDYSTGLSGDLLTHEYDAVNQIMHVGIPHSATSSGGVYFFKDGRTVPDVLQTTFEW
                     PDRDLTMLYSATLASSRNRGKVFMGHDASMEVSNILAITVDQDSTRYADKIKEGIIPT
                     DTPFYTYVPGQNSSDSVTSPTELYFAKRGLLYTYVNGKRYDTTHLHIREWLECIRQGK
                     TPSCNIDAAFQEAMTAHMGTRAYLEGRTMYWDKDKEEIVRGELA"
     gene            18592..18999
                     /locus_tag="ACZPB4_10495"
     CDS             18592..18999
                     /locus_tag="ACZPB4_10495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6249 domain-containing protein"
                     /protein_id="HIR1098673.1"
                     /translation="MNELWIPILGVICAVGMPVLLGIIASYMTIKSKHEEKMAMIEKG
                     IVLEEAMRPERRPNRYNTLRNGIFMIGLSLGVIVGMMVDSAFTYDSDWFFLLVPAITI
                     MFGGVAFIIYFFLSRSLMEKERLEDEKKMRLEE"
     gene            19010..19573
                     /locus_tag="ACZPB4_10500"
     CDS             19010..19573
                     /locus_tag="ACZPB4_10500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HIR1098674.1"
                     /translation="MDERKWIERILAGDTQSFSCLVAKYEKMAYTIALRILENREEAE
                     EAVQDAFVKMYRALSDFHFDSKFSTWFYRIVYRTALTALRQQRMFVSYEEAGPVDLSN
                     DEVESATALLEREDRKEMIARTLKKLPADEALLLTLYYLEECSVEEICQITELSASNV
                     KVKLFRGRKRFYEVLQDKMKLETADLL"
     gene            19576..19953
                     /locus_tag="ACZPB4_10505"
     CDS             19576..19953
                     /locus_tag="ACZPB4_10505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098675.1"
                     /translation="MNEKDIDHLTRKLMRGTAEQPSASLNSRIMALIIQEKKRVYKYY
                     IKKRFTPVGIFSIFVAYMLVLVGILYLVKLSPGGAETVLGSLRAYFPIVLTIASGISC
                     FFLFTQLDNWLKREEIRRQNTSK"
     gene            complement(20000..21085)
                     /locus_tag="ACZPB4_10510"
     CDS             complement(20000..21085)
                     /locus_tag="ACZPB4_10510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat-containing
                     protein"
                     /protein_id="HIR1098676.1"
                     /translation="MNTTHVKLSPAVLLTFVLLLCNLSAIARPQEKIKKKEISQSYSV
                     SAGDRLQVENRYGNITVTHWNQNTVAIRVEVECKARSEERAQENLDRIQIETKKIGGI
                     VSAVTTIKKEMNSNSNNESMTINYYIQMPPKLAADLNQKYGNINLPSDNNGNMDIHVK
                     YGNLNAGNFIANAMIEAKYGNIEVGNLQDAQLDLGYVGTAKIRNAKDLTIDSKYSNLD
                     IQDIQSLRMEIKYGNLTIESVSRLDMEIKYSDAKIGTLKDALNVSSLSYSNLKIRNLS
                     PSFSKVNVESHYGNLEVALPAKTSFRIVAENMKYSSCDVNGFNITRKHFDDEDRDKNY
                     TYEINGGKQPTIHFEGNRYGNLKVKAN"
     gene            complement(21111..21647)
                     /locus_tag="ACZPB4_10515"
     CDS             complement(21111..21647)
                     /locus_tag="ACZPB4_10515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098677.1"
                     /translation="MDKLKNFIDANRDAFEEDEMLPEGHFERFEQKLPKPRKNRAALY
                     SLSAFVIAASIALLLLFRLPGGTGLPEPAQKTTAQTCETQEEIEELRLYYNMQMNEVL
                     TQMKKLYKQDRTPGAEELLQESKRILTDNYMFEETILPTLPCSNDGLFAMTQHYSNSL
                     EGLTLMLKQMEQVTDNQK"
     gene            complement(21650..22180)
                     /locus_tag="ACZPB4_10520"
     CDS             complement(21650..22180)
                     /locus_tag="ACZPB4_10520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HIR1098678.1"
                     /translation="MDKVTEHLIEGCRREDRSSQLKLYKQYAQRLYIACLRIVGNSSE
                     AEEAMQDSFLKIFTRLDQYHDGQCFEAWMHRIAIHTAIDYVRRQAPDQEELSDNLAEP
                     ETDGPDEEEIQYSVAQIKEATTKLPAGYRIILSLYLFEGYDMEEIASILKIQPPSVRS
                     QYLRAKRKLLDIIAAN"
     gene            complement(22313..23074)
                     /locus_tag="ACZPB4_10525"
     CDS             complement(22313..23074)
                     /locus_tag="ACZPB4_10525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NigD-like protein"
                     /protein_id="HIR1098679.1"
                     /translation="MKTLRAFLLVIGIALVSLTLPSCLDDDNSYSLGDIWIAVATVVP
                     EGNNVYYLRLDDGDKLWPAATNYPNYQPKPNQRALVNFTILADSTQSNLGGFSHYIKV
                     NAIHNILTKSIAKNEGAANDSIYGTDPVSIYNNNMWIGDGYLNIYFETLWGGKTAHFI
                     NLIQPDAENDPYTLEFRHNAYDDPQYTIGAGRVAFNLSSLPDTKGETVDLVVNYWTSD
                     GKQAYKLKYNSDKTKMEGTSQGYTNDSISNITDMK"
     gene            complement(23169..24302)
                     /gene="lpxB"
                     /locus_tag="ACZPB4_10530"
     CDS             complement(23169..24302)
                     /gene="lpxB"
                     /locus_tag="ACZPB4_10530"
                     /EC_number="2.4.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008915 - lipid-A-disaccharide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid-A-disaccharide synthase"
                     /protein_id="HIR1098680.1"
                     /translation="MKYYLIAGEASGDLHASNLMAALKENDPKAEFRFLGGDLMRAVG
                     GTLVKHYREMAFMGFIPVLLNLRTILNNMKTCQEDIRRYQPDVVILIDYPGFNLKIAK
                     YVKTQLGLPVYYYISPKIWAWKQYRIRDFRRYVDRMFCILPFETKFFRKLNYSVDYVG
                     NPSVDSVAYYKEHQAIPKDTFIKEEGLANKPILALLSGSRKQEIKDNLPTMLKVASAY
                     PDYQPVIAGAPGIDPAYYQEYIGSYPAKIVFGKTYPLLQHSAAALVTSGTATLETALF
                     RVPQVVCYYVVAGQLASFIFKHFFHTKYISLVNLIGGREIVQELFGARFSESQIQDEL
                     GRILQDPAYRKRMLDGYDKIIHTLGMPGASKRTARLIVESLGS"
     gene            complement(24327..25094)
                     /gene="surE"
                     /locus_tag="ACZPB4_10535"
     CDS             complement(24327..25094)
                     /gene="surE"
                     /locus_tag="ACZPB4_10535"
                     /EC_number="3.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008252 - nucleotidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'/3'-nucleotidase SurE"
                     /protein_id="HIR1098681.1"
                     /translation="MTNERPLILITNDDGVWAKGINELIECLKDLGDLVVFAPDGPRS
                     GMGSAITSLVPIKYTLLKKEEGLTIYSCTGTPVDCVKLAINEVMERKPDLLVSGINHG
                     GNMAICVNYSGTMGATAEGCIFNVPSMGVSLLDHAADADFSECCRLGRMLARRVLKEG
                     LPHGTYLNLNVPKLPQVKGLKVCRQADGRWVREFKRSENASGEPVFWLTGAFESAKPI
                     HPDNDMLALDSGYASLVPCKIDVTDYDFMATLNNWIL"
     gene            complement(25220..>25336)
                     /locus_tag="ACZPB4_10540"
     CDS             complement(25220..>25336)
                     /locus_tag="ACZPB4_10540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HIR1098682.1"
                     /translation="EGRQEEKHSIALNLKKLGVSIEQIAFATGLSIEEIEKL"
BASE COUNT         6836 a         5114 c         5978 g         7408 t
ORIGIN      
        1 aatacgctgg gtgagttctt ggcaaacgta ggtaagactc agttgcatat cgccgagaca
       61 gagaaatacg ctcacgtgac tttcttcttc aacggtggcc gcgagactcc gttcgatagc
      121 gaggagcgta tcttggtccc ttctcctaaa gtggctactt acgacttgaa accggaaatg
      181 agcgctttcg aggtgaaaga taaattggtg gacgctatca atacgaagaa attcgatttc
      241 atcgtagtga actatgccaa cggtgatatg gtaggccata cgggtatcta caaagcgatc
      301 gagaaagcgg tcgtaacgat cgacgcttgc ttgcacgata cggttgaggc cgctaaagcc
      361 aacgactatg aggtaatcat catcgctgac catggtaacg cggatcacgc cttgaacgag
      421 gatggcactc cgaatacggc tcactccttg aaccctgttc cattcgttta tgtgacagcc
      481 aacaaggacg ctaaagtaga ggatggtatt ttggccgatg tggctccttc aatccttcac
      541 atcttgggct tgaaacagcc gaaggagatg actggcaagt cattgattaa ataagagcta
      601 ggcgcatctt atgatccaga tagatgacac tttagtaagt cttgacgtta tcgagcgtta
      661 ttttttatgt gatctttcca aatgtaaggg ggagtgctgc gtggaaggag attccggcgc
      721 tccattagag gattcggagt tggcgaagct ccagaaagta ttgcccatta tctgggatga
      781 tttatccccg aaagctcaag aggtcattaa taagcaaggc gtagcttata tcgatgagga
      841 aggcgatacg gttacctcta tcgtgaacgg caaagattgt gtctttacct gttacgacgc
      901 cgatggtact tgtaaatgcg ctattgagaa agcataccgg gaaggtaaga cggatttcta
      961 taagcctgtt tcttgccatc tttacccgat acgtgtcact cagtatcggg atttcaaggc
     1021 cgtgaactat catcgctgga gcgtttgtaa ggcagcggag atcttaggaa agaaagagca
     1081 attgccggtt tataagttcc tcaaggagcc cttgatccgt aagttcggcc aggcttggta
     1141 taaggccttg gaagagtgtg cggaggaatg gaagaagcag cgtgaggagt agcttttaga
     1201 tcgtttataa atataaaaaa tcccttcagt ctctcccttt gataactata cgttaaaaac
     1261 ggatggaggc tgaagggatt ttgttttata gtcgctctat ttcctcaagg gaaaggccgg
     1321 tgcatttttg gatgataaga ggggttattc cctcggcttt catattacgt gccgtagatt
     1381 ctttcccttt ttgcagtcct tcttgcaatc ctttttgcaa tcctttttcc atgccttctt
     1441 ccatcccttt tttcatgcct ttctcaacgg cgaagtccaa ggtgttataa taatcattat
     1501 acatcttcca ctccgcctcg tactgcgctc gttgtttggg ggtgaggttc gccatggatc
     1561 cgatgcgttc caaccgctcg aatatggcct tgcgtgcctt gaaaggcatt ctgtctaatg
     1621 tatccatatg ctttagtaca taaatccaac gttcaaaatc tgtctcgcat tcttcctcct
     1681 ctttgttgaa tcgaggaagc tcaatataga tctggcggaa cttggggttg aatacctgtc
     1741 cgttctcccg atccgccagc acgatgtccc ttcggaactt tccttcgttc ctgttattgt
     1801 ttggcctgtt ctcctcgtct agcgtgaagt tcaagaaaaa aacaccgtac acggccgcca
     1861 gctcatagtc ccatgttccc tttatcccct gttccaccac cgagtgcgag aggtagtata
     1921 aggccctgtc cttgaagtgg ggctgttccc tgttctgcat ctcgattatg atccgttcgc
     1981 ccttgtcggt ctcgcaatgg atatcgaaga tgaccttcct tccttgctct gtctcgggca
     2041 atcgctcatt gttcattgtt catgatcctc aggtccatga tagtatgctc ccctttgagg
     2101 aggtcgttca ggaactcgat taaaatgtcc ttgttcattt ccctgccgaa tatgtgcttg
     2161 aagccgaaat cggtgaaggg gttgataaat tttcccatag tgtttatagg ttctagtgat
     2221 taataggata tagatggttc ttttccatct ttggcgataa agatacgatt tttattatat
     2281 ggggcattca tttaggcttt aaaaaaacac gtacgtcttt ttttcggaaa tatcttgtgt
     2341 agtttgagtg aagacgagat atagtgaacg cataaaggat acagccttaa agctaaaggt
     2401 gggttaatga ggctttccgc gtcaaatgta agccatagct tattttaaat gcgggaaaca
     2461 tgtgcctgta caggccctga taaccaagaa acgggccctc tcattggctg ttgaagtgaa
     2521 taactgacgg cttgtcgagt gaataactag cggctatacc tagccgctaa ctgacggctt
     2581 gggaagtgaa taactaatca cttggaaagc ctttttatac cggaaccaac aaggtcttct
     2641 cagtggcttt gggatgcggt tcagttatcc tgcggggctt ttctatgtcg attattctgt
     2701 tatagccctc acggatggat ggtaagcgaa gcggcgataa tcatgacagt ttgcgcgaaa
     2761 caaggctgtt tgtttgacat acctcttctt tggagaagtc taaccagaga gaagaaatag
     2821 gtgaaaaggg cctttttgtc tcttatttat aggtaaaagg tcgcttttcc ggtgagaaag
     2881 gtggtgtttg cccatgcgaa tatatgcgtt agccgacgca accgtatgtt ttagccgacg
     2941 taaccgtatg tattaggtga tacatacggt agtaatcccc atcgcatacg atagaaatag
     3001 ccttcacata cggatgaatt acaggtttta gccttaagaa tatgaattag gatgaataat
     3061 tttcgccaga atgaaagggc atattccgtt atcttgttat ggaataacta cttgcgaata
     3121 ttttttctcg ttttacggga ctatatgtat aatctcccgg aaaattcgat tctcaagggc
     3181 tttaatttac aaagtgtcac aatgacaatc cgtaaattcc ggatgacttg tttaatataa
     3241 tattaatgta cgcctgtaca ttaattaatg ctatactata aaagttgatg aataatagat
     3301 tgaaatgata tctggagtat ggaaacgact agtttaaacg aacgattctt ttagtcattt
     3361 gcaaaggtac gcgtttcttc gatacttgca acccttccgg gctatttttt tacagcttat
     3421 tctctttctt atcaatagga taggttatcc tttacgaaac aagcgattcc ttcaacaaac
     3481 ctttctattt accccttata aaacgcaaga ttaaaacctt cgtttagact agtcgtttta
     3541 caacggaaaa gcctacgata cgatgacgta atgagctgat tatcttaata aacactagta
     3601 ttaatattaa ttttagaatt atgaacaaaa agttttctac tcttttggct ggtgctgcgc
     3661 ttctgggtgc ggtgacggct aatggtgctg ttaagctgaa tcaaggagcg aataacggtc
     3721 tttatcagct taaggcaggt tctgctttct tgagtattac cgaaaattcc acgactcacg
     3781 aagatgaaat caaaatggtt tctcactctt ccgcaaattt aggaggtaca atgtggtgtg
     3841 taacggttga tgccgagaat caaggacaga atcctaagta tgatttcacg aacaagatcg
     3901 gaaagttttt aggtcttgag atcagcacga tcaaaggtaa ggcggcggct ccgttagctg
     3961 ctgtacctgc tgttgtcggt ggtgatcttt ccggttggaa attctctcct gtatttaaga
     4021 atggtgtgga gaaatccgtt ctctattctt atttcacgaa tgactctgta atcggtttga
     4081 aggtgaatac tagtggcgat gtagaaatgg ttaaaactat agctactaca gctggtatta
     4141 ctgccgctgg tttcactgaa tttgagttgg tagaggccgc ttcgatcgtt gtctcaggtg
     4201 ctgatgaatt gaatacgatc tttggtaccc aagataagaa agctggtatc acattgaagt
     4261 ttactccgga tgtattagga gatggagcgg taaactactt taccgagaag aagttcacgg
     4321 ttgaagcttc tggaactgct aattatttcc atgtattgag agccgactct tcttacttgt
     4381 acgtagatac tgcttatacg aatgctgtgg gtggagctaa gttcttggct tataactgga
     4441 gcaacttaaa ggatacttat aagactggta ctaagaatca tgctactccg aaagattcta
     4501 tcaatgctac agatttatca gaccaatata aatttatgtt tacatattgg ccttcaaatg
     4561 acagcttgga gattcaggtt aaacaatctt tgttaaaaac aagtgagacg tattggaaag
     4621 atgttactgc tactacagct atgcaaaatc agcatatctc tttgcaagag ttgctgaaag
     4681 acaaggttcg tatcttgacg gtagatgcgg ctcaaaatac taagattgag ttaggtttcg
     4741 caggttgcaa agttttgcct actacaaaga caactgttga tgatggtgtt tatgtaatca
     4801 gaaatgctaa gactggtaag tactatgctg ctccgcttta taatgaatct gcatctagta
     4861 aatacgagtg ggtgactttg gatattcaag atgctgctca tatgcctgct tatcaatggg
     4921 ttgtgttgaa gaagaacgta acagataaga ataaggtttc tgctgtagat ttgtataacc
     4981 gtgagtataa tgacggtacg gctgctgatg cgactctcca attgaataaa aatgcggggg
     5041 ctacttatat gtatgctgct agttttggtg actctttgga atttatccca gtcgctaaag
     5101 aaatctatac tgataagtat gtgggttata agcatctgac taatgatgag ttgatcacga
     5161 acaaatatac tttcaactac tggcatccgt acgcatctga taaatttatc ggtgttaagg
     5221 attctacgat gaatgtgtta gagggtaaga aagcgttcac tcttaagtct tcttacaaag
     5281 aacatgctta tggctataat ccttctgagg aggtttccgg taatgcggac aagaagatca
     5341 cgggtcgtat ccctggcttg gtgagaccgg taagaacgat gtatatcatt actaatggtg
     5401 agactacttt ccgtaatcat aacgtagcgg tagagtctaa gtataaattg agtaagtatt
     5461 atcctaatac tacgaatgac tctgtttact tcaaggagaa caaccatatt gagggtaacc
     5521 attactatgc tatccttgag gctacttccg caggtgctat cagcactcat aaagcaggtg
     5581 tttccgatta tgatgcttcc gctactttga aagctcaggt aatgggtgag actcgtactt
     5641 ccgcattcgc tatcgctccg gacgagactc cgttgtatcg tcaattcaat aatgaacttc
     5701 ttggtgagaa cgttgataat tcagctgata gcttgatgtt caaggaaact atccgtggtg
     5761 aatatttgat ggatgagcat aatggtgcct tgttgaacaa ggatgttgat tacgctggta
     5821 tctggagtga gggtaaggct gatggtaagt tggctttccg tattgacaca gcatggttaa
     5881 ctcgtggcgc aggtaaggtt aaacctcaat acttggtatc cgcttatcgt gagttgatcg
     5941 agggtgagaa gatcattcct tgtactgaga caggcaagca tatcactgct gatggtcaag
     6001 ttacagaaga tccatatcaa tgtgtacatg ctgttcatgt gaagactcca gcattcatct
     6061 atggtaagta tttggttaac tactcagact ctgctgccgc tgttgctgct cgcaaggaag
     6121 ctcttaaccc gtacttgttc aatacgaaag cagtttcaaa cagtagctat actcgtgtag
     6181 gtttcgttcc tgccgttcaa tatggtgata ccttgatcgt tttgacaggt aagtacaaag
     6241 ctatgactgc tgatcaattg aagaatgagg gaatcgagtc tattatggct gtttataaga
     6301 aagattatcc gaaattcatc aacgtattgt ctggagacaa gcataagaac gtaacttggt
     6361 cattccgtta tgtaaatccg gataaggctg ctttagctta tgtagatgga aaagagggtg
     6421 agaacaactc attcttgatc gagtctaacg tatatgcaac aggaacagat ggtgataatc
     6481 aatatcagac tatcaagggt gatttggcaa aagctatcgc tcctaatgaa gctgccgcat
     6541 ggttgaagat gcacaatggc tgcttggtat tgacagatgc tagctctaca tttggtgccg
     6601 ctaagactgg tggtgatgga gcattggtat tcaacgcata ttctaagact gaagatgatg
     6661 atatggtaac atctaacgat aacatcaaca atgttgaagg agtatctgta atcgctggta
     6721 acggtactgt aactatccaa ggcgcagctg gcaagtctgt agttatcact aacatcttag
     6781 gtaaggttgt cgctgagaca gttcttactt ctgacaacgc tacaatcgct gtaccggctg
     6841 gtatcgtagc tgtagctgtt gatggtgaag aggctgttaa ggtagtcgta aaataagact
     6901 aaccgatgga ctaaacgaat agaggcgggg agacccgcct ttatgtaata tataattaaa
     6961 taactatgcc gcaataaaga agtatcccgt gacgggtgaa cacgtggcat attaatacta
     7021 aagtaattaa aagttcttcc gcaggtatcc tcgtgagaag agagagcgga tcaaaaaaca
     7081 agccccgtgg gatttatcct atggggcttt tatttatcgt atcgccacct tgcgtaccgt
     7141 atcgccaatg cggatgatat aatatccctt tgcgatatct acgacatatt cggcggtgga
     7201 ctgcttgact tcgatttctt tcaccttgat gcctacgaca ctgtagattt ccaagatact
     7261 cccgacagga gcgttctcta ccttgatgcg attctcgtag gccgtgattt cgataggaga
     7321 gggatcttct tgcctagaag caaatgtctt gactcccgat ttattagctt gcgcgtaaac
     7381 cggataactt gcggagaatg caagtgccaa agcgatgata tgtataagct tcatttactt
     7441 gtccctaaat tcgtacaaat gtagaaagtt ttccgcatat tagaaagtaa ttagctttat
     7501 ttcgtaaaac ggatgtatga ttatacgcta agcctcatac cttcctctcc taagatcgtg
     7561 ccgggaaata tcttgtctgc ttctttcttt aacggtgcca tatcctcgta acgagccgag
     7621 taatgaccga taaccaatcg cttcacttgg gctttataag caatctcggc cgcttggcgg
     7681 gcggtagagt ggaaggtctc tttcgcacgt gcggcgtcac attcagcgaa agtcgcctcg
     7741 tggtataata aatccacccc ttcaatgatg gggattatag atgggtgaaa agctgtatcc
     7801 gagcaataag cataccgttt gggagcgacg gcagggcggg ttaagcgggc attcgggatt
     7861 acctctcctt ccggggtgac gaaatcagcg ccccttttga tctcttgcat catacggacg
     7921 ggaacttgat agaaatctgt catctcccgg atgatatgcg cttctttggc tttctcggcg
     7981 aataaatagc cacaacaggg tatacggtgc tttaacggaa tggaataaac gcttaaggag
     8041 cgatcttcca taaccaacga atgagttgtc gggtcgatta agttaaaacg gatctcataa
     8101 ggcaaccctt tgcaaaagat atcaagtacc ggacgcatat agctctcgat ctctttcggc
     8161 ccatgaataa caagttctcc attacgtccc agcataccta atgtagagat caatcccggt
     8221 agcccgaagc aatgatctcc gtgtaggtgg gagatgaaga tatgatttaa acggctgaat
     8281 tttatacgca tacgacgcat ttgcacttgc gtgccttccc cgcagtcgat catgtatagt
     8341 ttatctcgta aatctactat ttgagaggtc gccagatggc gtgtcgtggg caatgcggaa
     8401 ccgcatccca atatgtttat atcaaaatca gccatttgtt gtctatggga ataattgagt
     8461 gcaaagataa tacaaaagca tttctgttct gtgaaaaata acaaaaaaac aaagtgtaat
     8521 gtatgcagga tgaggtggat tccatatatt tgtttgctgt ccttcgggaa agcgaatata
     8581 cagtcggtaa atagacttaa gatatttttt tctaagcctt aactaacttt ttctttttgt
     8641 ttaaaacggt taaatgtaga aacggccaag cgtgagcttc gccgtttcct ttttttattg
     8701 ttaatttgaa atctaaatac ctatatctaa taaattatgt catttaacaa tctacgatta
     8761 tgaacaagaa ttttatctct gtttttcttc tgatgctcgc tatgggcgta tctgttatgg
     8821 cccagagtta tgaggaagat ttggcttttt tcaaggaacg agtaaagact ttaggctcgg
     8881 atgagttcgg agggcgtaag cctttgaccg agtatgagac gaaaacaatc cattacattg
     8941 ctgatgaatt taagaaacta ggtcttcagc ctgctaatgg cgatagttat ttccagccgg
     9001 tgaaggaaat atctactttt acccgtccgg taaagaataa gatcacggtg aaatgcgcga
     9061 aaggctctat ggatttgaag ttctcggatg atattgtcgt ttggacgaac cgggggactg
     9121 aaaaggtagt tattcctact acggattatg tgttctgtgg gtttggtatt aatgcgccgg
     9181 aatatggatg gaacgattat gcgaatgtag acgtgaaggg gaaaatcgtt atcgctatgg
     9241 tgaatgatcc cggtttttat gacgcgtctt tgtttcgcgg aaagaacatg acctattatg
     9301 gtcgttggac ttataagttc gaggaggcgc aacgccaagg tgccgcaggt ttattggtcc
     9361 ttcataacga ggcggccgct tcgtatggtt ggaaggtctg tcaggcttct cacgtgcaaa
     9421 caaatatcgc tctttgctcg gagacaatga atgcggaagc tttgggcatg aagggatggc
     9481 tctcggagga ggcttgcaag aaaatgttcg cccttagcgg attgaatttt gatgagacga
     9541 ttgccgcggc gaagaaaccg ggtttcaaga gttttacgat gaaggcgaag agtaaggtta
     9601 tattaaatgt aaagatgacc gtaggcgagt ctcataacgt ggcggctgtt ttaccgggca
     9661 cggacctgaa agacgaatac ttggttttta ccgctcactg ggatcatttt gggatcggca
     9721 cgccgataga tggggacagt atctataatg gcgctagcga taatgcttcg ggcgtggcaa
     9781 ccttaatgtt attagctaag aaatatcaat cattgcctgt tcatccccgt cgttccatcg
     9841 tattcgtggc ggtgacttcc gaggaatgtg gcttattagg ttctcagtac tattgtgagc
     9901 atcctttgtt ccctttatct aaaacggcta ttaacttgaa ctttgacggc acagctccgc
     9961 gtgagcgtac ccatgatatt tctctccggg ctgcgggtaa gacggatacg gatgccttgg
    10021 tgatcgctat ggcctcggca caaggacgga ccgtgaaggt tattaccgaa gatcctgcgg
    10081 gtggttattt ccgttccgat cattttaatt tcgtgaaaaa aggcgtacct acgattttag
    10141 ttggtggcgg taaggattac gtggataaag cacgccatga ggctaaaccg aaagtttacc
    10201 ggtatcacca accgaatgat gagtatgatg aatcttggtg ggattttgat ggggctatgg
    10261 aagatatgaa cttaatgttt agtatcggtt tagttatcgc caacaatgat gagatgccta
    10321 agtggacaaa agaggcggac ttccaaaggc aatagattaa tgtgccaatg tagcaatatg
    10381 ccaatatgct aatgtgtcaa ttaagatact atcacttgta ttctcacttg acattgacat
    10441 attggcacat tggcatatta tttaatttgc acattattta ataggtatga cctccttctt
    10501 gcatttcctt actattgatc ttatgtagat caagcgctct ccaagcatag aaaatgtagg
    10561 ctaatacgaa tggaacgaga atagatacat agctcattac tttcaacgtg aatgggcttg
    10621 agcaactatt ctggatcgtc aatgaacttt gtagatccgc caaagatggg tagtaagccg
    10681 tattattcca tcctgcgcaa agtaataaag ctaatacggt caagacagtc cctgctcccg
    10741 cgaaccagat gccttttctc caagtcttcg agaatatcgt tttccctatg ccgaatagca
    10801 cgccaaccac gccaatcaat aatacggcta acacgattgg catctcgatc aggttcataa
    10861 aatacttata cggttgcata aatacttctc cggtatccgg atttacggca aaaccgtcca
    10921 ccaacaataa acggatcaag aatgtcaaga aaaagacgag gaacaagatt gtctccggta
    10981 tcaattgttt ccggctttta gcgacaatct ccggatcatc gatattgttg ataaaataga
    11041 gtagggccag agctcgtgcc aagaagaaaa ctgctagtcc taggcacaaa ttccaaaata
    11101 ccaaagccgc ctctaatcca tgccaaggat tggcccacgt ggaaatgacg ggcatggcta
    11161 catcagtcaa ctgttctttg ttaacaataa attcagcgcc gttaaagaag gtcgctacag
    11221 cggttccgag taagatcgga cctgctatac cattgatcat aagaaatact tgatacgtct
    11281 ttttcccgag taggttgcct tttttcgctt gatactcgta agatacagct tgtatcacga
    11341 agcaaagcaa gatcagcatc catacccaat aggctccgcc gaagcttgtg gaataaaata
    11401 aagggaaaga ggcgaagaaa gcacctccga aagtgaccaa cgtagtgaaa gtaaactccc
    11461 acttacgccc ggtcgagttc aataacattt tttgctgtat ctccgtcttg ccgatagtga
    11521 agagtagaga ttggcctcct tgtacaaaaa gaaggaatac taatagcgct ccgagtagag
    11581 ataccagaaa ccaccagtaa tgttgtaaca atatatatgt actatccata ggactttcta
    11641 tttaagaatt gatatttgaa aattgaaaat tagtgggcgg cagcttccgg ccctttcttg
    11701 atggccttaa ccatgattcc aatctctgcg atcagcagga tcgtaaataa gataaggaac
    11761 aggtagaaag tggtctgtac cgaggatggg tttaacttgg atatcgaagc gctggtcggc
    11821 aagatatcct gtatagccca aggttgacgt cctacctccg ctacgatcca accggcttgt
    11881 cccgctatat atcctaaagg tatagaccat aggcccacgt attgcaacca acgtgtatta
    11941 gcgattttcc cttttttatc ccatatcaac gtaataatga atagtaagat gaagaaacaa
    12001 ccaaggatca ccatcacacg gaaagaatag aatgtcaatc ctacatgcgg gattaactct
    12061 gccggatcct taatataacc atatccgaaa taggggaaat tctcttccaa ggttaccctg
    12121 tattgtgcgg ctgctgcggt atctttatct ttaaccgctt tgcgataatc agctaacgct
    12181 ttgatggcgg ttttaccttt ctctattttt tctttggcgg agagcgctac cgttccttta
    12241 ttggtcgtat aacctccctc tattaagttt acgattcccg gaacgtatgc gttcatgtca
    12301 cgttctgcta agaaggagag gagtttgggg aacttaatgt caaaaataaa tgcgttctgg
    12361 ttatccagat aactcgtctt tgccggattt aagatgccga tacctacgag tcctactccg
    12421 ttgccaccct cataaagacc ttccatggcg gctagtttca tcggctgctt ttgagcgact
    12481 tggtaagcgg agccatcacc cgtccagata ataaggatgg aggctaccaa cccgaatata
    12541 gcgctgacct tgatacttga caaagcgaat tcggtattcc gtttctttaa taaataccag
    12601 cagctgattc ctagtacgaa caaggcgcct acgatccaac cggacaatac cgtatggaaa
    12661 aacttattaa tggcgacagg cgataaggct acggcccaga aatcgaacat ctcgttacgg
    12721 accgtatccg gattgaaatg cataccgacc ggatattgca tccatgcgtt agcgatcaag
    12781 atccagagag cggaaagagt agcgccgata atcgtcagcc aagtggaggc gagatgaaag
    12841 cgtttgctaa ccttgtccca accaaaaaac ataacagcga taaaggtagc ttccataaag
    12901 aaggcgagaa ttccctcgat agccaaaggt gccccgaaga tatccccgac aaaccaacta
    12961 tagttagacc agttggttcc gaactcgaac tcgaggatca atcccgtagc gacaccgata
    13021 gcgaaattga taccgaataa tttcatccaa aattgggcgg tctttttcca tgcctcatta
    13081 cctgtccgat aataaatcgt ctccataata gcttggataa cgccaagtcc tagtgttagt
    13141 ggcacgaaga gccaatgata catggcagta agggcaaatt gagccctcga ccaatcgatc
    13201 aatgaagtgt caatgttttc aatcatattt attaatgttt taaggattta ttgcccgttg
    13261 tatgagttcg ttcgatacgt ggttctcctt ctcactatcg ctatcgaatt gcccgagata
    13321 attaggaaag aagaataatc tcaggataaa aaacatgata aacaatttga ctagaatgat
    13381 tagccaaaga gtcttgccca gcttcatctc ccggaatcct tccagataaa agcgatatat
    13441 tcgtatgaat gcagattctt ttttcatata gttgttctca tttaagataa cagttgttaa
    13501 tatgaatatg ttttcatgtt tttacaaata tatccaaact gcgttaataa aataccccca
    13561 atcctataga taatatttat gaaattataa ataagatcta tcctgtctgt taaaaaaaac
    13621 tattttaaat aagaaagcgg tcttttgatc ttgtcaataa tacagcattg gctatatttg
    13681 cgacaatttg ttgcctgtaa aggtgtaaag acacatgaaa tatcattgtt aagtgctaat
    13741 ctataaaaaa ttattactat gtctaacatt tctagaagat cttttcttca aaaaggtacg
    13801 gctgccgcag cagctttgac tattgttccg agtgcggtcc taggtaaaac ccatggtcat
    13861 atcgctccaa ctgataaatt gaatattgcc ggtgttggta tcggaggtat gggtaacgct
    13921 aacttaaaga acatggagac taccgagaat atcgtagctc tttgtgacat cgactggaag
    13981 tactcaaaac ctgtattcga ccgtcatcct caagctaaaa aatactggga ctatcgtaag
    14041 atgtatgatg agatgggtaa atctattgac gctgtgttgg tagctaccgc tgaccatact
    14101 catgcgatga tcacagctga cgctatgacg cttggcaaac acgtatacac tcagaaaccg
    14161 ttgactcact ctgtttatga gtcccgtttg cttacgaact tggctaagaa gtatgacgta
    14221 gctactcaga tgggtaacca aggttcttca ttggctgaag gtgtagattt gatctgtgaa
    14281 tggatttgga atggtgagat cggtgaggtt actaaagtag aatgcgctac caaccgtcct
    14341 atctggccgc aaggtttgaa cgctcctgag aaagttgata agattccttc tacattgaat
    14401 tgggatttgt ttacgggtcc tgctaaattg agaccgttta ataagacata tcatccttgg
    14461 aactggcgcg gatggtggga ttatggtaca ggtgcgttgg gtgatatggc ttgccacatc
    14521 ttacatccgg tattcaaagg cttgaattta ggctatccga caagagttca aggttcttct
    14581 acattgttat tacaagactg tgctcctaac gctcagcatg ttaagttggt attcccggct
    14641 cgtgataata tgccaaaggt agctatgccg gaggttgaag ttcactggta tgatggtggt
    14701 atgatgccgg atcgtccaga aggattccct caaggtaagg aattgatggg tgaaggtggt
    14761 ggattgtgta tcttccatgg tacgaaagat acattgatct gcggttgcta cggtgttaac
    14821 ccatggttgt tatctggtcg taaaccgaac gttcctcaaa cattgcgccg cgtgaaagac
    14881 gctatgaagg gtggtcacga acaagactgg attcgtgctt gtaaggaaag cgcaggcagc
    14941 cgtgttcaga cgaagtctaa cttcttggag gctggtccgt tcaatgaaat ggttgtaatg
    15001 ggtgtattgg ctgttcgttt gcaaagattg aataaagaat tgttgtggga tggccctaac
    15061 atgagattta cgaatatcga tccgaatgag acaatcaaga tcatcaagaa agatacattc
    15121 gaggttatcg atggtgaccc gaaattcaag acagagtgga cggatccaat taatgctcaa
    15181 gaatttgccg caggcttgat caagcacaac taccgtgaag gctggaagtt ggtagatatg
    15241 ccgagataat agttttaact caataaataa aatgaaaaag tcagtattat tagcaagtgc
    15301 tgctatcatg atgtgttatt tcacatcttg tggtggtgga aagaaaacag aagaagctcc
    15361 tgcagctgct gagactacaa cagaagccgc aactcctgag tacaagctca tgacagatct
    15421 tcctactgta gatatcacga ctttcccgaa agataaagag ggtagatatg tgatcttcga
    15481 tggtaagaca ttcaatggct ggagaggtta tgaccgtgct gacgttccgg gtgcttggac
    15541 aatcgaggac ggagcgatca aaatcaatgg ctctggtgct ggtgaggctg gtgcttccaa
    15601 cggtggggac ttgatcttcg ctcataagtt gggtaacttc gagcttgagt tcgaatggaa
    15661 agtaggtaaa ggctctaact ctggtgtatt catcatgatt caagaggtag agggacaacc
    15721 ttcttacatc tctgctcctg agtaccaagt attggataac gagaaccacc ccgacgctaa
    15781 gttaggtaag gatggcaacc gtaaatcttc ttctttgtat gacatgattc ctgctaaacc
    15841 gcagaacgca aaaccgttcg gtgagtggaa caagggtaag atcatgtgct ataagggtac
    15901 agttgttcac tatttgaata gcgatgaacc tgttgttgag tatcacttgt ggactccgca
    15961 atggaaagaa atgttggata atagcaaatt tagcaaagac aaatggccgt tggcttatga
    16021 gttgttgttg aattgcggtg gcgctaacaa agaaggtttc atcggatttc aagaccacgg
    16081 ggatgatgtt tggttccgta acattactgt taaagttttg gattaatcgt atcaagcaca
    16141 ttttagcata aataacgccc gaggcctaaa tctatgattt tagcttcggg tgttgtgttt
    16201 ttaataatcg actttttcta aaccaatttt ttaggaccaa gaaatgaaaa tagaacaagg
    16261 ttacacgaaa gcgcagatga cttggctgat gatgctgcgt ctttttatag gttggcactt
    16321 tatgtatgaa ggcctagtaa aaatcatgaa cccaaaatgg acatctctac cctatctact
    16381 cgattcaaag ggtcccgctg cttcattttt tatcaaattg actcaagacg acagtttgat
    16441 gacgaccatc aacttcttga atgagtgggc tctgttattg atcggcctag gcttgacttt
    16501 aggctgtttg tatcgtttat cttctgttgg aggtatgatt cttctcgcta tgtacacgtt
    16561 atcccacccc tctttcgtgg gagcgagcta tatgatgccg tttgaaggct cttatttatg
    16621 gattgacaag aaccttgtgg agttcgccgc tttaggcttg atgtgcgtat tccctacatc
    16681 acaaatcata ggattcgatc gtgtgttagg acgtgtgtgt ccgatattgc ataaacttaa
    16741 atttatttga tacccatggc aacagaagat gcaaagaata ctccttctca ggagcaaatg
    16801 cccgataaag gacgtcggga cacattgaag acattggcta cagtgcctat cttaggtgct
    16861 ttggcatatg gcgtttacca aaaaaggaaa gacgctttaa gaggccgtaa catatcagat
    16921 gtatttcagg taagtaacag gcaggcctcc tatttagagc cgcaaggcga tggtaagaag
    16981 atccgtatcg gtttggtagg cttcggtatt cgtggaaagc aattgatgcg tgccgcaggt
    17041 ttcgctgagc cttcttggat cgataagatg aaagaggcta ataagttgaa taagaaagac
    17101 acgcgttatc agcaatatat ggagcaagat gatctgaata ttgagataac cgcggtttgt
    17161 gatatatttg atgtatatgg tgaggccgct gtattgaccg gttccaatat ccatcgtgag
    17221 ggtagcggcg gtaagttcgg gcctgctccg aaacgttacc ggacttatca agagctggta
    17281 acggctccgg atgtggatgc cgttattatc gctggtccgg accactggca tagcacgatc
    17341 gctatggctg cggcacgtgc cggaaagcat gtatattgcg agaaaccgtt atcatggacg
    17401 gttcctgaga cgtatatggt tcgccaagtg atcaaagaga ccggcgttgt atttcagtta
    17461 ggtcaccaag gacgtcagac cgattgctat cagaaggccg aggagattat cggtaacgga
    17521 ttattaggcc ctgttaactt gatcgaggtt tgtacgaacc gtaactctcc aaatggtgct
    17581 tgggtatatg atattattga aggctctaat ccgaatacga tcgattggaa gcagttcgag
    17641 ggtgatcctg agcgtattaa ggaatatatg gattatatga catccaacaa gcttgaaaga
    17701 tatatcggtc cggacgagcg tagcaagttc agtctggaac gtttcttccg ctggcgttgc
    17761 tggtgggatt atagtacagg cctttccggt gacttgttga cacatgagta tgacgctgtc
    17821 aaccagatca tgcatgtggg tatacctcat tccgctactt catccggcgg tgtttatttc
    17881 ttcaaggacg gacgtacggt acctgatgta ttgcagacta ctttcgagtg gccggatcgt
    17941 gacttgacga tgttgtatag cgctacattg gcaagtagcc gtaaccgtgg caaggtgttc
    18001 atggggcatg atgcttctat ggaggtttcc aatatcttgg ctattacggt tgaccaagat
    18061 tccactcgtt atgcggataa gatcaaggaa ggtattattc ctacagatac cccgttctat
    18121 acctatgtac cgggacaaaa tagctcggat tccgttacat ctcctacgga gttgtatttc
    18181 gctaaacgtg gtttgctgta tacgtatgta aatggtaaac gttatgatac gactcacttg
    18241 catatccgtg agtggctgga atgtatccgt caaggcaaga ctcctagctg taatatcgac
    18301 gctgctttcc aagaagctat gactgcccac atgggtacgc gtgcttatct ggaaggacgt
    18361 acgatgtact gggataagga caaagaagag atcgtaagag gtgaacttgc gtaagtatct
    18421 aaaaagacga taaataactt tcccaagaag cgaacttcat aaatggatgg agttcgcttc
    18481 ttttatttgt gcatgtataa aatttcttct cttttttgta accgatttgt gattactcat
    18541 gtcttattga taaaagcgaa taatttatta aacctttaaa gaataaaaga tatgaacgag
    18601 ttgtggattc ctattttagg tgttatttgt gcggtaggta tgccggtatt gttaggtatt
    18661 atcgctagtt acatgaccat taaaagtaag catgaggaaa agatggcgat gatcgagaaa
    18721 ggaattgtgt tggaagaggc tatgcgcccc gagagaaggc ctaatcgtta taataccctg
    18781 cgtaacggta tttttatgat cggtttgtca ttgggtgtga ttgtcggtat gatggtcgac
    18841 tctgctttca cttacgatag cgattggttc tttttgttag ttccggctat tacgattatg
    18901 ttcggtggag tagcttttat aatttatttc tttctttccc gttctttaat ggagaaggag
    18961 agattggagg acgagaagaa aatgcgtctg gaagaataaa cgataccgga tggatgagcg
    19021 aaagtggata gaacgtattt tggcagggga cacgcaaagt ttctcctgcc ttgtcgcgaa
    19081 gtatgagaag atggcttata ccatcgctct tcgtatcttg gaaaatcgcg aggaggcaga
    19141 agaggctgta caggatgcgt tcgtgaagat gtatcgtgct ctttccgatt ttcatttcga
    19201 tagtaagttc tcaacatggt tttataggat tgtgtatcgt acggcgttga cggccttgag
    19261 acaacagcgt atgttcgtga gttatgagga ggcgggccct gtagaccttt cgaatgacga
    19321 ggttgaatcg gctacggctt tattagagcg tgaggaccgg aaagagatga tcgcacgtac
    19381 gctgaaaaag cttccggctg atgaggcctt gttgcttact ctttattatt tggaggaatg
    19441 ctcggtggaa gagatctgtc agatcactga attgagcgct tctaatgtga aagtaaaact
    19501 attccgtggg cggaaacggt tttatgaagt gttgcaagat aaaatgaaat tagagacagc
    19561 tgatttgtta tgaatatgaa tgagaaagat attgatcatt tgacacgtaa gttgatgcga
    19621 gggacggcgg aacaaccttc ggcctcatta aactcccgta ttatggcatt gattatacaa
    19681 gagaagaagc gggtatataa gtactatatc aagaaacgat ttacacctgt aggcattttt
    19741 agcatatttg tcgcttatat gcttgtgtta gtaggcatct tgtatttggt taagctttct
    19801 ccgggcgggg cggaaacggt tttaggctct ttgcgagcct atttcccgat tgttttaacg
    19861 attgcttccg ggatctcttg tttcttcctg tttacacaac tcgataactg gttgaagaga
    19921 gaagagatac gccggcaaaa cacctcaaaa taaaaatatc cggttgtaga gacggggcac
    19981 gccccgtctc tacaaccgat taattggcct tgacttttag atttccgtaa cgatttcctt
    20041 cgaagtgaat cgtcggttgc tttccaccat taatctcata ggtgtaattc ttgtcacgat
    20101 cctcatcgtc aaaatgcttg cgggtgatat tgaaaccgtt cacgtcgcag cttgaatact
    20161 tcatgttctc cgctactatc cggaaagaag tttttgcggg aagcgctacc tctaaattcc
    20221 cataatgaga ttctacgttc accttcgaga aagagggaga caagttccgt atctttaagt
    20281 tactatagct aaggctactt acattcaagg catctttaag ggtcccgatt ttagcgtcgc
    20341 tgtacttaat ctccatgtct agtctgctta cgctttcaat ggtgagatta ccatatttaa
    20401 tttccatgcg taaagattgt atatcctgta tatccagatt ggaatatttg ctgtctatcg
    20461 ttaaatcttt agcgttgcga atcttggcgg ttcctacgta gcccagatcc agttgggcgt
    20521 cctgcagatt tcctacctcg atgttaccat atttggcctc tatcattgcg ttggctatga
    20581 aattacccgc attcaggttg ccgtatttta catggatatc catgttgccg ttattatcgc
    20641 ttggcaagtt gatgtttccg tatttctggt tcaagtctgc ggcgagctta ggaggcatct
    20701 ggatataata attgatcgtc atggactcat tattcgaatt gctattcatc tccttcttta
    20761 tcgtagtgac cgctgagaca ataccaccta tcttcttggt ctcgatttgg atacggtcca
    20821 agttctcttg agcacgttcc tcgctgcgag ccttacattc tacctcaacc cgtatagcta
    20881 ccgtattctg attccagtgg gtaacggtga tgtttccata acggttttct acttggagac
    20941 gatcaccggc gcttacgctg taggattggg atatctcttt tttcttgatc ttctcttgtg
    21001 gcctagctat tgccgataga ttgcatagca gcaatacgaa agtcagcaat acggcgggac
    21061 tcaattttac gtgtgtcgtg ttcatgattg atatgtatta attgttatta ctatttctgg
    21121 ttatccgtga cttgttccat ttgcttaagc atcagcgtga ggccctccaa gctattgctg
    21181 taatgctggg tcatggcgaa gagaccgtcg ttggaacaag gcaaggtagg gagtatcgtt
    21241 tcctcgaaca tataattatc cgtgaggatc cgtttgctct cttgcaataa ctcttccgct
    21301 cccggtgtcc ggtcctgttt atacaacttc ttcatctgcg tcaatacctc gttcatttgc
    21361 atattgtaat atagacgtag ttcctcgatc tcctcttggg tctcgcaggt ctgggccgtg
    21421 gtcttttgcg cgggttccgg cagaccggtc cctcccggca agcggaataa gagcaacaaa
    21481 gcgatagagg cagctatgac aaaggccgat aggctgtata gggccgcacg gtttttccgt
    21541 ggcttcggca gtttttgctc gaaacgttcg aagtgacctt cgggaagcat ctcatcttcc
    21601 tcgaatgcgt cacggtttgc gtctatgaaa ttctttagtt tatccatgtt taattggctg
    21661 ctataatgtc taacaatttc cgcttagcgc gtaggtactg gctacggaca cttggcggtt
    21721 ggattttcag gatagaggcg atctcttcca tgtcatatcc ctcaaagagg taaagcgaga
    21781 ggattatgcg atagcctgcc ggcaacttcg tggtggcttc ctttatctgt gccacggaat
    21841 attggatttc ttcctcgtcc ggtccgtccg tttccggttc ggccagattg tcggaaagct
    21901 cctcttggtc cggtgcttgg cggcgtacat aatcgatggc cgtatggata gcgatgcgat
    21961 gcatccatgc ctcaaagcat tgcccatcat gatattggtc caagcgtgtg aagatcttga
    22021 ggaacgagtc ctgcatggct tcttccgcct cggatgagtt gcctacgata cgcaagcagg
    22081 ctatatacaa tcgctgtgcg tattgtttgt acaactttag ttgcgagctc cggtcttccc
    22141 ggcggcaacc ctcgatcaga tgttcggtta ctttgtccat ttgcttatat aaacgagagt
    22201 gatgccttga ccgttgcatc ttgtagcgta aaaatacaaa aaaaagaaag gcatcatctc
    22261 gacgcctctc ctcctgaact aaatgataaa aataaaagtt atgtgggaag gtttatttca
    22321 tgtctgttat attggagata ctatcgttcg tatagccttg cgaagtacct tccatttttg
    22381 tcttatccga attatatttc aatttataag cctgtttccc gtcggaagtc caatagttta
    22441 cgacaagatc gaccgtctct cctttggtat ccggcaagga agacaaattg aacgccacac
    22501 gtccggcccc gatcgtatat tggggatcat cgtaagcgtt atgcctaaac tccagcgtat
    22561 aaggatcatt ctcggcatcc ggttggatca ggttgataaa gtgggcggtc ttgcctcccc
    22621 agagtgtctc gaaatagata ttcaaatatc cgtctccgat ccacatatta ttgttataaa
    22681 tacttaccgg gtccgtacca tagatagaat cattagccgc tccctcgttc ttagcgatgg
    22741 atttcgtaag gatgttatgg atcgcattca ccttgatata gtgggagaaa cctcctaggt
    22801 tactttgggt ggaatccgcc aatatcgtga agttaaccaa ggcacgttgg ttaggcttcg
    22861 gctgatagtt cggatagttc gtggcggcgg gccatagctt atccccgtca tccagccgta
    22921 agtaatatac gttattgcct tccggtacta cggtagcgac cgctatccag atatcaccta
    22981 aagaatacga gttatcgtca tctaagcaag agggtagggt gagggatact aaagcgatcc
    23041 cgataaccaa taaaaaagct ctcaacgtct tcattccttt tgtttcttaa aaagttcaca
    23101 tttcatcgtt ctatgaagaa agatgtaagt tcggggtgaa atgctgcaaa agacgttaat
    23161 aaaagatgtt aagaaccaag ggattcaacg attagccgtg ccgtacgctt tgaagccccg
    23221 ggcattccta gcgtatggat aatcttgtcg tatccgtcta gcattcgttt tcgataggct
    23281 ggatcttgta ggatgcgtcc tagctcgtct tgtatttgcg attcggagaa gcgggctccg
    23341 aatagttctt gtacgatctc ccgtcccccg atcaggttca cgagggatat gtatttcgta
    23401 tggaagaaat gcttgaaaat aaagctggcc aactgtccgg ctacaacgta gtagcaaacg
    23461 acttgcggaa cccggaacag ggcggtttcc aaggttgccg tgccggaggt taccaaggcg
    23521 gcggcactat gttgtagcaa gggataggtt ttaccgaaca cgatcttggc aggataagag
    23581 cctatgtatt cttgatagta ggcaggatcg atgcctggtg ctccggctat taccggctgg
    23641 tagtcgggat atgcggaggc tactttcagc atggtcggta aattatcctt gatctcttgt
    23701 ttgcggctac cggatagcaa ggcgaggata ggcttgttgg ccaatccttc ctctttgata
    23761 aatgtatctt tggggatcgc ttgatgctcc ttgtaatagg ctacggagtc tacagaagga
    23821 tttcctacgt aatctaccga ataattaagc ttccggaaaa acttggtctc gaacggcagg
    23881 atgcagaaca tacgatctac ataacgccgg aagtccctga tgcggtattg tttccaggcc
    23941 catatcttgg gggatatata gtaatatacc gggagaccca attgggtttt cacatatttg
    24001 gcgatcttca ggttgaatcc cggatagtca attaaaatga cgacatctgg ctgatagcgg
    24061 cggatatcct cttggcacgt cttcatgtta tttaagatgg tgcgcaagtt cagcaatacc
    24121 gggataaagc ccatgaacgc catttcccgg taatgtttga caagggttcc tccgacggct
    24181 ctcatcagat cgccgcccag aaagcggaac tcggccttcg ggtcattctc tttcagggct
    24241 gccatcaaat tcgaggcgtg caggtctccg gaggcttctc cggctatcag gtaatacttc
    24301 atgaattgaa aattgagaat tgaaaattaa aggatccagt tgtttaaggt ggccatgaag
    24361 tcgtagtccg taacgtcgat cttgcagggg actagggagg cgtatccgct gtccagcgca
    24421 agcatatcat tgtccgggtg gatgggtttg gcgctttcga aagctcctgt caaccagaat
    24481 acgggctctc cgctggcgtt ctcggaacgc ttgaattcac gtacccaacg accatccgct
    24541 tggcgacaaa ctttcaaccc tttcacttgc ggtagcttcg gcacgttgag gtttaagtag
    24601 gttccgtgcg gtaagccttc ttttaatacc cggcgtgcca gcatacgtcc aagacggcag
    24661 cattcggaga agtcggcatc ggccgcatgg tccagtaagg atacacccat ggaagggacg
    24721 ttgaaaatac agccctcggc ggtggcaccc atcgttccgg aataatttac gcagatagcc
    24781 atattccccc cgtggttgat accggagact aacagatcgg gcttgcgctc cataacctca
    24841 ttaatcgcta atttaacgca atcaaccggt gtcccggtgc aactatagat ggtaagtcct
    24901 tcctcctttt tcaacaaggt atacttgata ggaactaagg atgtaatggc actacccatc
    24961 ccggaacgag gtccatcggg agcgaatacc accaaatcgc ctagatcttt caggcactca
    25021 atcaattcgt taataccttt ggcccatacg ccatcatcat tcgtgatcag aatcaacggt
    25081 ctctcgtttg tcatatcgtt ttatccttat agttgtcgta caaaggtaac aataatttgc
    25141 gaacaatggt tggggtgtga ggggtgggag ttgtcctttc gcctaatcag ttgttgatca
    25201 ggcgaaaggt ctcagattat tatagtttct ctatttcttc tatggagagg ccggtggcaa
    25261 aggcgatttg ctctatacta actcctaatt tcttaagatt aagtgctatg gagtgtttct
    25321 cttcctgtcg tccttc
//
LOCUS       DBMDTB010000059        25129 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_699_length_25129_cov_12.087582, whole genome shotgun sequence.
ACCESSION   DBMDTB010000059 DBMDTB010000000
VERSION     DBMDTB010000059.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 25129)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 25129)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25129
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_699_length_25129_cov_12.087582"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..395)
                     /locus_tag="ACZPB4_10545"
     CDS             complement(<1..395)
                     /locus_tag="ACZPB4_10545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1848 family protein"
                     /protein_id="HIR1098683.1"
                     /translation="MITTDSGEQVEALAPIIISASRSTDIPAFYAKWFFNRLAKGYCV
                     WYNPFNRRKMYVSFERCKAIVFWTKNPKPILSYLHELDRRGIHYYFQFTLNDYVSEGF
                     EPNVPSVTQRVETFRELSEMIGKERVIWR"
     gene            518..1054
                     /locus_tag="ACZPB4_10550"
     CDS             518..1054
                     /locus_tag="ACZPB4_10550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HIR1098684.1"
                     /translation="MKNVLILSSSPRRGGNSDTLCDEFMQGAIESGHRVEKVFLRDKT
                     IHPCTGCGVCSQYKKPCPQKDDAAEIIGKMLAADVIVMATPVYFYAMSAQMKTLIDRC
                     CGPYTEMKNKEFYFIATAAEDDNGIMDRIVANFMGFLDCLENPTVKGTLFCGGVWHVG
                     EIEGNPTLRQAYEQGKRV"
     gene            1088..1261
                     /locus_tag="ACZPB4_10555"
     CDS             1088..1261
                     /locus_tag="ACZPB4_10555"
                     /inference="COORDINATES: protein motif:HMM:NF037716.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclophilin-like fold protein"
                     /protein_id="HIR1098685.1"
                     /translation="MHTSDLILWGANTVVLFYETFSSSYSYTRLGKKENPAGLADVLG
                     GGNVRVARFSLSK"
     gene            1501..2142
                     /locus_tag="ACZPB4_10560"
     CDS             1501..2142
                     /locus_tag="ACZPB4_10560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HIR1098686.1"
                     /translation="MAEYIKQEMCDLNGTGEKPVYYRMKIQRNMDMEDFVERITYPGS
                     GLSRGSVIQVMTTVAEHLAYCMAEGQSVTLDGIGTFTPRLGVVKDKEIDSLDGDEPKR
                     NARSIEVNGINYRADKELVRETNLRCNLRRGGISRVWKSPFTEEERRTRALDYLHEHP
                     FLRIQDYMAITGLKRSSANRELLRLSSDPASGLTISGYGSHRVYVRRKTEGDR"
     assembly_gap    2167..2266
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<2267..4471)
                     /locus_tag="ACZPB4_10565"
     CDS             complement(<2267..4471)
                     /locus_tag="ACZPB4_10565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-rhamnosidase-related protein"
                     /protein_id="HIR1098687.1"
                     /translation="MNKLLIAFFLFLLPFGWIKATASSHPESFPWKAQWINTERCQSA
                     TNTWLIYRKSFGVTDVPDQLIARIAADSKYWLWINDQLVIFEGGLKRGPSPSGTYYDP
                     VDIAPYLTKGSNTIAILLWHFGKDGFSHINSGKAALLFEAIAPGLEIVSDASWQCALY
                     EAYQNTEAPFPNYRMPESNIRFDARQAITNWNRTSFEGSLPGAVCVGKAGKAPFGDLV
                     ERPIPQWKNSGLLSYVSVRESLKGDTLFCRLPYNAQITPYLKVEAEAGNTIHIRMDNY
                     EGGSERNVRAEYITREGEQEYESYGWMNGHEVYYIIPEGVKVLDVKYRETGYNTDLAG
                     SFHCDDPFYDELWQRSARTLYITMRDNYMDCPDRERAQWWGDEVNELGEAFYALSPSG
                     QKLAVKGIHELMNWQREDGTLYAPVPAGNWDKELPLQMLASIGWYGFYTQYYYSADSS
                     FVPVIYDRMRRYLHEVWQVDKSGLVIERQGAWSWGDWGEHVDMGVLTNCWYYLALKAE
                     RAFALQLGKDKDADEISRMMRSIERCFDTKFWTGSAYRSPGYKGETDDRSQAMAVVSG
                     LASKDKYPALTKVLKKEYHASPYMEKYVLEALFQMGEPAFALERMKQRYTRMLDYAEY
                     TTLFEGWGIGAEGFGGGTINHAWSGGPLTLLSQKVCGIEPTSPGFRTFKISPQLGPLS
                     EASASLETHYGTIQVSIKKKGKRMKFDLQIPEGTSAELIKPNGTRKHLGPGHH"
     gene            complement(4616..7213)
                     /locus_tag="ACZPB4_10570"
     CDS             complement(4616..7213)
                     /locus_tag="ACZPB4_10570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HIR1098688.1"
                     /translation="MYIIIEYMKQTICIYAFAALLLGGCKSNNELTIPTNLRTEYLTE
                     PIGLDTSSPRFTWEYSGNEEGFKASRYEVRIGTSPDDLRPYAEGMALKPHTRYYWNVT
                     VWDGEGRPCATSETASFETAKFDPSDWSASWITDHKDKEFEPAPLFRKSFPVGKEVKD
                     ARVYVASAGYHELFINGERVGTNYLDPGYTHFDKRILYVTHDVTSLLKQGDNAVAAVL
                     GNGWYNEQSVAVWNFHEARWRNRPRLLCELRITYTDGTTEVIGSDGTWKISTGAYTYN
                     NIYSGDKFDARLEEAGWKTAHFDDSKWEAALPAQAPAPLLVAQQMPGIRITEEVRPVS
                     MKRFSDQLYVYSFPKNMSGLCRLKVKGEAGTRITLKHGELLKKDGRLEQGNINVYYHP
                     VKPDEVFQMDVFTLKGTGEEEIFMPSFSYHGFQYVEVESSRPVTLTEENLTGLFMHTD
                     VRPSGSFACSNPLLNKIWEATMQAYRSNLHSIPTDCPQREKNGWTADAHIAIDLGLLG
                     FDGITLYEKWMNDIIDNQREAGEISGIIPSSGWGYGEWPGPVWDAVMFIIPNALYDYY
                     GESRSIERLYPTMLRYLDYLKTKEKDGYLPFGLGDWVYWKATTNNEYTSTAYYYLDYK
                     LMARFASLLGKDAAPYQEKANTLKSLINQKFFNAETSVYAEGTQTAQALALYLGLVPE
                     GKEQLVADKLREVVAGNNYFLDFGLLGSKTVPAMLTKYGYIEDAMKMITKTEAPSWGY
                     WVETMGYSTLPETWTLSPKFADASLNHVFMGDVSAWMMNQLAGINHDDSAPGFRHIRI
                     TPHFVKELDWAKGEYHSVRGRIASEWKREGDKVMLTVTIPADCSADIVVGDQTETVSA
                     GTHTFTYPA"
     gene            complement(7234..8982)
                     /locus_tag="ACZPB4_10575"
     CDS             complement(7234..8982)
                     /locus_tag="ACZPB4_10575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-rhamnosidase-related protein"
                     /protein_id="HIR1098689.1"
                     /translation="MRKKLIILFIGIGSFKLFAQQRDHRTREYIAPVRIVWQQDSSRI
                     TGANHLLVPGNGQSDLANNRLCVLKSTPTEHPALLLDFGKELQGGLQLVTGMPPSHDP
                     VSVRVRFGESVSEAMCEIDGANGASNDHAMRDFVVSLPWLGVQEIGNSGFRFVRIDVL
                     GDSTELQLKEVRAISTFRDIPYLGSFRCNDERLNRIWKTGAYTVHLNMQEYLWDGVKR
                     DRLVWVGDLHPEVMTVSTVFGYNEVVPKSLDLIRDITPLPSWMNGISSYSIWWLLIQR
                     DWYYYQGNLAYLQEQRSYMTALLRHLISKVDPSGQERLDGNRFLDWPSSENTPAIDAG
                     LQSLMIQAMRAGEELCTVLGEDALASECRMVASKAIKFSLRKKSRFPSEKDRITPGDK
                     QAAALMALAGIMDAKEANERCLAVDGAKGFSTFYGYYMLRAMALAGNYQGALDVIRTY
                     WGAMLDVGATTFWEDFNMEWLPDAGRIDELVPAGKKDIHGDYGAYCYQGFRHSLCHGW
                     ASGPTSWLSEYVLGVQVVEPGCRTVRIIPHLGDLEWVEGTFPTPYGVIEIRHEKGADG
                     KVISHINAPEEIRVTP"
     gene            complement(8986..9786)
                     /gene="rhaD"
                     /locus_tag="ACZPB4_10580"
     CDS             complement(8986..9786)
                     /gene="rhaD"
                     /locus_tag="ACZPB4_10580"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HIR1098690.1"
                     /translation="MIILRNNERLMAEIDRIAEVAGYLWTKGWAERNGGNISVNLTTL
                     LSEEEKALPALVSSIPLQEAMTALCGHVFYVTGTGKRMRYVAKDPFANGSLIRIAADG
                     KSYDILAEQPIQPTSELPSHLLMHNFLRAKGRDNRVVLHTHPTDIIGMTHCKPFLDSE
                     KITRTLWRMIPECRIIVPKGVGIVPYEIPGTLALAHATIRQLEEHDVVFWEKHGILAV
                     GEDLIECFDAIDTLSKSAQIYFSARMTGYEPEGMTEQQLDDLVPAFGL"
     gene            complement(9798..10823)
                     /gene="rhaT"
                     /locus_tag="ACZPB4_10585"
     CDS             complement(9798..10823)
                     /gene="rhaT"
                     /locus_tag="ACZPB4_10585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005638211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose/proton symporter RhaT"
                     /protein_id="HIR1098691.1"
                     /translation="MEIGIGLLIIAIGSFGQSSSYVPINKIRDWSWESFWLVQGIFAW
                     LVFPYLGAMLAVPEGSTLLELWRSPGSLGAVIYGMLWGVGGLTFGLSMRYLGVALGQS
                     IALGTCAGFGTLFPALFGGTNLFEGTGLILLTGVCITLAGIAVIGYAGSLRARNMSEE
                     EKKAAVKDFALTKGLAVALLAGVMSACFNLGLESGNEVLAKAREAGASDLFALNPVIL
                     LVTLGGFCTNAVYCIFQNVKNGTGKDYFSVSGGTLLNNVLFCALAGVLWYSQFFGLGM
                     GKSYFSDSPVMLAFSWSILMSLNVIFSNVWGILLKEWKGVDRRTIVVLITGMCILILS
                     LLYPNIV"
     gene            complement(10823..12082)
                     /locus_tag="ACZPB4_10590"
     CDS             complement(10823..12082)
                     /locus_tag="ACZPB4_10590"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008740 - L-rhamnose isomerase activity
                     [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0019318 - hexose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HIR1098692.1"
                     /translation="MTKDSLIQQAFEVAAERYAAVGVDVRKALEDMKKISLSLHCWQA
                     DDVSGFENQGGSLTGGIQVTGNYPGRARTIDELRRDVLKAKSYIPGNHRLSLHEIYGD
                     FQGEKVDRDEVEPHHFESWIQWAKENDFKLDFNSTSFSHPKSGDLTLANPSDDIRNFW
                     IEHTKRCRWISDEMGKAQNDPCMMNLWIHDGSKEVPASRLRYRRILEESLDEIFATEY
                     KWMKDCIEAKLFGIGLESYTVGSYDFYLGYGAKKNKIVTLDTGHFHLTESIADKVSSL
                     LLFTPEIMLHVSRPIRWDSDHVVILNDDVQDLAREIVRCDALDRVHIGLDYFDATINR
                     IGAYVIGSRATQKAFMLALLEPIALLRQYEDEGKYFQRLALQEEAKSLPWGAVWDMYC
                     LQSGVPVGESYIAEIEKYESDVTSRRQ"
     gene            complement(12121..13542)
                     /locus_tag="ACZPB4_10595"
     CDS             complement(12121..13542)
                     /locus_tag="ACZPB4_10595"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008993 - rhamnulokinase activity
                     [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0019301 - rhamnose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HIR1098693.1"
                     /translation="MKEYNFLAFDIGATSGRAVLGTLKDAKFEMKEIHRFPNPMVELH
                     GRFYWDIYHLYTSLIESLTICARQRIRLHSIGIDTWGVDFGYVALDGSLLGLPRAYRD
                     PYTDGAPEDFFKRIPKEEVYKRTGIQVMPFNSLFQLFRAGQDSFIPQEVAEKILFIPD
                     LLAYMLTERMVCEYTIASTSQLLNPETHKFDYKLLEAVGVSPTLMCPVVMPGTLIGRL
                     SEPIARKTGIGEIPVIAVAGHDTASAVAAVPASSPNFAYLSSGTWSLMGIEVEKPIIN
                     EVSFKNNFTNEGGIEGTTRFLKNITGMWILERCREQWKRSGLDYSYDDMVRMAELSEF
                     TSLINPDDPRFANPESMLREITAYCEETGQAVPASDADYVHCIFYSLANRYKEVLEIL
                     KSMSPHPIERLHVIGGGSRNDLLNQLTANAIGIPVLAGPSEATAIGNCLIQAKSAGLL
                     TDCWEMRRLIATAFPPKEFYPER"
     gene            13637..14524
                     /locus_tag="ACZPB4_10600"
     CDS             13637..14524
                     /locus_tag="ACZPB4_10600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HIR1098694.1"
                     /translation="MNELRNDLLRYLTISATDEEWGIVVTTVGYQFIPPGCAYPLSRH
                     PEKYNFKPQTGRILNEYQLVYITKGSGYFSSQSCKSQKINAGTMILLFPGEWHSYYPD
                     RETGWDEYWVGFRGIHIDKRVEKKFFTKEEPLHRIGLSATIVGLYEDILKFASEEKSG
                     YQQMISSIVLHILGSVYYKEKNNSFTNTYVVDKINEARILMKENIEDPLSPEEIAARL
                     GLGYSWFRRMFKEYTGVSPAQYQLQQKLLRAKELLTSTPLTISEIAYSLHFENAGQFS
                     TFFKKKEGVTPSEFRDRTH"
     gene            complement(14532..15377)
                     /locus_tag="ACZPB4_10605"
     CDS             complement(14532..15377)
                     /locus_tag="ACZPB4_10605"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HIR1098695.1"
                     /translation="MKKLIIFVSLLFLAMAYGKAEDKEVLKIATFNLRMDTPSDGENA
                     WFHRKDMVNDLIRFYGFDLFGTQEGFTHQLNDILRLSDYRFIGVGRDDGKDAGEHCAI
                     FYRSDRFKVLDQGDFWLSEHPEKPGRGWDGTCCNRICTWGKFEDLKNHKQFYFFNVHY
                     EYEGDVARRESSNLMISRIKSIAGNQPVFLTGDFNAFPTEEPIRILNDSGFLNDSYKI
                     TKEAPFGPVCTYHGYDSTIKTEERLDYIWVTDSIQIDKYGVLTNTLYGHTPSDHFPVM
                     VVAEF"
     gene            complement(15396..17165)
                     /locus_tag="ACZPB4_10610"
     CDS             complement(15396..17165)
                     /locus_tag="ACZPB4_10610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0019867 - outer membrane [Evidence IEA];
                     GO_function: GO:2001070 - starch binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RagB/SusD family nutrient uptake outer membrane
                     protein"
                     /protein_id="HIR1098696.1"
                     /translation="MKKTLIYIISVIGLFSCDLDEVPVSEVSKEPVFSTENGLELYAN
                     SFYEILPTPSAAHQADNMCDYAARALVPNFILADAYGPQQSDGWDWEKLRNINYFIQN
                     CTDPRVSESVRMNYIGLARFFRAWFYFDKVKRFGDVPWINKAMEVDDPDLYAARDSRT
                     LVMDSVLADLDFACEHITLTSDQTSSLITKYVAQAFKSRVCLFEGTFRKYHTEYGLKE
                     SANAWLNEAVKAAEDVIANSGFKLYTANGTTKSYRDLFISVKPVTTEVMLAAVCDKSL
                     SVLNDANWYWTSATYGPRLNLIRTFVNTYLMEDGTPFTDKEGYKTMVFMDEVKNRDKR
                     LQQTIRMGDYKRIDGGVQTPAPPIFSYTYTGYQPIKYCLDDVFYDSGANNDNSIPLIR
                     FAEVLLNYAEAKAELGVFTDADWEKTIGALRGRAGITGGLTARPTKADPYLQANYFPE
                     ITDPSLLEIRRERGIELVFEGLRFSDLLRWKKGNLMTMPWNGFYVPELDKPMDLNEDG
                     ILDVCFTMNENVENPISGVTYVVVSEMKAGKVNPQRLSGNTKGELTWLNNIPRVWEDK
                     HYLYPIPDLDIIMNPNLTQNPGW"
     gene            complement(17179..20688)
                     /locus_tag="ACZPB4_10615"
     CDS             complement(17179..20688)
                     /locus_tag="ACZPB4_10615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HIR1098697.1"
                     /translation="MNNKRQFVKGRNCLYAIFFLLFFSLRLLAVEAVDKKISVSFSNL
                     PLKEAIHEIEVASGYTFFYDGNKIDLTQKVSLNVSNQPIESALNSMLRTTDLSFEITS
                     KQIALFPRQNASASAGKPSRKITGTILDPLGDPVIGANVVVKGTTNGTITDMDGNFSV
                     EASDNDILQVSYIGFMPQDIAVKGKSELTVTIREDTQKLDEVVVVGYGTQKKVNLTGA
                     VEQVTSEVFDNRSISNVTQALQGTIPNLNISMTDGKPNRTAEYNIRGTTSIGQKGSAL
                     ILIDGVEGDPSMLNPNDIASVSVLKDAASAAIYGARGAFGVVLISTKNPSKDKTSVTY
                     SGNFTMKSPTKVPDVVTDGYTYAKYFNEAWSAYYDYSQTPQNINKTLKFSQEYLEELE
                     RRSGISGLPEVEIGPNGDYVYYGNTDWYKELYKKSTFATDHNISVSGSSGKTSFYVTG
                     RYYGQDGLFRYNTDDYKLFNMRAKGAVQVFDWLKVEDNLEYSSMTYHNPLNVGEGGGI
                     WRNIADEGHILAPMFNPDGTLTHSAAYTVGDFWYGKNGIDTEQRILKNTVSATASFLK
                     DKLRIKGDFTFQNNDNDQTQIRVPVPFSRRPGVIEYVGSSKNDIQNTNKTTSYLASNI
                     YGEYEDTFKEVHYFKAMVGYNYEESRMKNVKVLRNGLIFDDAEDLNMALGQTINTEGG
                     YSKWRISGGFFRLNYVFNDRYLLEVNGRLDGSSKFPSDSQYAFFPSVSAGWRVSQEPF
                     WKVPEEIFSNLKVRASYGSLGNGNIDPYSFQELFKIKQSSLVLNGIRPQYTDQPAVIP
                     LGLTWEKSTTLNLGLDFAFLSNRLQFSGDIYQRKTTDMFTVGMSLPAVFGTDVPKGNY
                     ADLTTKGFELSVSWRDQFQLASKPFNYEVRFTLADYQSTIDKYNNPEKKLGDDYYYEG
                     MKVGEIWGYETEGFFTSQADIDSHAKQPYFYAGATAGQWLPGDIKFKDLNGDGVIDYG
                     NNTVDNPGDQKIIGNSEPRFIYGINLSGDWNNFFVSAFFQGVGKQDWWPGSEASYFWG
                     MYNRPYNDMPKSHLGNIWTEENPNTYFPRLRGYSSEEPYAELNLKQTRYLQNIAYIRM
                     KNIQLGYTLPKSFISKLRMQNAKVYVSGENLWSWSPFYKYSKDLDVEAVRGSDRDLTE
                     GTSGNGYSYPILKSVSFGLSVTF"
     gene            complement(20859..21857)
                     /locus_tag="ACZPB4_10620"
     CDS             complement(20859..21857)
                     /locus_tag="ACZPB4_10620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecR family protein"
                     /protein_id="HIR1098698.1"
                     /translation="MNKHIPWQLIISRLKDEQDERGEKLFEEWLQGEGNAHLYQELEG
                     LWREIREEASSYTPDTAFYWQQLESRMSQENKAPKVVSIWKFRMAVAAASILLIISLT
                     FSFLYTGGDRAVYSNKLSYSALSGKSRIVLPDSSVVWLNSGSTLEYAADFMENREVAL
                     NGEALFDVTKDNRHPFVVLASEVKVKVHGTCFNVNSYPKEENIRVTLFRGSVSLEAGG
                     KEAYLYPGEIAALNKRDKTLNITSADMFYESFWASESVRFEAKSLRYITRYLEKWYNV
                     KIEVDPTIPDSQAYTFTIKDESLEVILRIMSRINPIAYTFDEDDHVQIMHVEPSKK"
     gene            complement(21943..22491)
                     /locus_tag="ACZPB4_10625"
     CDS             complement(21943..22491)
                     /locus_tag="ACZPB4_10625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma-70 factor"
                     /protein_id="HIR1098699.1"
                     /translation="MDKTIDDLFILKLIKAGDRLAFKHLFELYFTPLCRFVHLYMKKP
                     GAAEDIVVDIFASFWERRETLQIQITLKAYLFQSARNRALNYLRDNERFISKDDFSSL
                     ERFENDETLETQELQRLIHEAIFSLPPKCRDVFNKSRMDNLSNKEIAEQMNISVKAVE
                     GHISRALKQIRAYLGDAYHYLW"
     gene            22706..24250
                     /locus_tag="ACZPB4_10630"
     CDS             22706..24250
                     /locus_tag="ACZPB4_10630"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1098700.1"
                     /translation="MRITYLLLSLVLCLCPVMQAQNTTNQFMKQAQSSLEKKDYTKAR
                     YLFLQAYKSLSQQGDYKQAIDAGTQAAYLYYCENYYQEAFDLCRQMNQFILTEELKLQ
                     KSLYEQRFQVTKERLEMYIKLKNAAQAQVQLNTLDNLASQAGDEKLSNNLLYTQAGYY
                     YTFGQNEQGDAAFQKLINQYKEKKEYDKVNDCYRNLISIARKANNAPLMERTYDKYIV
                     WTDSVKALTAEDKLGALQQKYDQSLQTIQEKDDKLSVKQYMIVGLITFVVILIAALLF
                     LGFLLLRFIVLNKKLKKIIQTTNEHSEQQAQFIQNISVQMEPTLNKLSASAKELQAVA
                     PKQAEDVWTRVEALKQFTVHIQELSSLENTLMEPYEVSSFNVGNFSKKIVEKVKGDIQ
                     PEVNLVTDVPQLEIKTNAEHLEQVLLHLLKNAALYTSSGNIRLEFKRKGAHVCQFIIT
                     DNGTGIPDDLKENLFKPFNEAKDLAQGDGLGLPICALMASKLNGTLSIDKEYKKGCRF
                     VLVLQI"
     gene            complement(24367..>25129)
                     /locus_tag="ACZPB4_10635"
     CDS             complement(24367..>25129)
                     /locus_tag="ACZPB4_10635"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070573 - metallodipeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HIR1098701.1"
                     /translation="MIRDKKALEAHLALWKDGEPADKKPIGYVLSIEGADSFITVNHV
                     ERAYAYGLRAVGPAHYGPGRYANGTDSTGHLNAMGKELLRTMDRLGMILDVTHLCDEA
                     FWDALDLYKGPIWASHNNCRAFVDHNRQFSDEMIKALIERDAVIGIALDAWMMVPNWV
                     RGESTPRGMNCGMEIMANNIDHVCQLAGNANHVAIGSDLDGAFGTEQCPYDLVTIADL
                     QKIFPILQYRGFTDDAINRIASGNWIEFLRKHLPE"
BASE COUNT         6859 a         6651 c         5306 g         6213 t
ORIGIN      
        1 aatcgccaga tcacccgttc cttccctatc atttccgaca actcccgaaa tgtctccacc
       61 cgttgcgtaa cgctcggcac attcggctca aagccttcgc tcacatagtc attcaacgtg
      121 aactggaaat aataatggat acccctccta tccaactcat gcaaataaga taatatcggc
      181 ttcgggttct ttgtccaaaa cacgattgcc ttacaccgct caaacgacac atacatcttc
      241 cgccgattaa acggattata ccaaacacaa taccccttgg ccaaacgatt aaagaaccac
      301 ttggcataaa aggccggaat atccgttgac cggctggccg aaatgatgat gggagcaagt
      361 gcctcgactt gctcaccgga gtccgttgtg atcattcttc cgtattatta tgtaattagg
      421 gtcataacat ccgtaatttg tctaccgcaa gatagggatt atctcgctat ttttgtatcc
      481 taaaaatgaa tgtagaacct aataaataac agtaaacatg aaaaatgtat tgattttatc
      541 ttccagcccc cgtcgtggag gcaattccga tacgctatgc gatgagttta tgcaaggggc
      601 gatcgaaagc ggtcatcgtg tggaaaaggt ttttctgcga gacaagacca ttcacccctg
      661 cacgggatgc ggcgtgtgca gccaatacaa gaagccttgt ccacaaaaag atgacgcggc
      721 agagattatc ggaaagatgc ttgccgccga tgtgatcgtg atggctacgc cggtctattt
      781 ctatgccatg agcgcacaga tgaagacgct gatagaccgt tgctgcggtc cttataccga
      841 aatgaaaaac aaggagtttt acttcatcgc cacggccgct gaagacgata acggcatcat
      901 ggatcgcatt gtggccaact ttatgggatt cctcgactgt ctggagaacc cgaccgtgaa
      961 aggaacgcta ttctgcggtg gtgtgtggca cgtgggcgag atcgaaggga acccgacctt
     1021 gaggcaagca tacgagcagg gaaaacgagt ataatactct tgatcgcgac caatacgttc
     1081 gggtataatc catacaagcg acctaattct atggggagcg aatacggtag tccttttcta
     1141 cgagaccttt tcctcgtctt acagctatac ccgtttaggg aagaaagaga atcccgcagg
     1201 gttggccgac gtacttggcg gaggaaacgt gagggttgcc cgcttctccc taagtaaata
     1261 acgctccgat accgcataaa taccttatcg gtagcagatg gattcttgtt tgcatactgt
     1321 ataattctac aaaccacgac gtggtctgta cagatcaaga cgtagaatat acaaatcacg
     1381 acgcggtcta tacattccac agtgataatt tggaaataga tcaagtaata agtatatttg
     1441 tatatagtaa gaagaatgtt tttaacttga agatacgaac aattatacct agtagcagtt
     1501 atggcagaat atatcaagca agagatgtgc gacctgaacg ggacggggga aaagccggtg
     1561 tattatcgga tgaagataca acggaacatg gatatggagg atttcgtgga acggatcacc
     1621 taccccggat cgggcttgag caggggtagc gtaatacagg tgatgacgac agtagcggaa
     1681 catctggcct attgcatggc ggaagggcag tcggtcacgt tggatggcat cggtacgttc
     1741 acgccccgcc taggcgtggt gaaggacaag gagatcgact cgctggatgg tgacgaaccg
     1801 aagcgtaacg cacggagcat cgaggtgaat ggcatcaact accgggccga caaggaactg
     1861 gtacgggaaa ctaacctgcg ttgcaactta agacggggag gtatcagccg tgtatggaaa
     1921 tcgcccttca ccgaagagga gcgccggacg cgggcattgg attaccttca cgagcaccca
     1981 ttcttgcgca tacaagacta catggctatc accggactaa aacgcagtag cgcaaaccgg
     2041 gagctactac gactcagcag cgatccggcg agtgggctca ccatatcggg ttatggaagc
     2101 caccgggtgt atgtccgcag gaaaacagag ggcgatcgct aatccaccca atggtgcccc
     2161 gggccgnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2221 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnatgg tgccccgggc
     2281 cgagatgctt gcgggtacca tttggcttta tcagttcggc ggaggtgcct tccgggattt
     2341 ggagatcgaa cttcattcgc ttgcctttct tcttgatact tacttggatg gttccataat
     2401 gagtctctag actggcagag gcttccgata agggacccaa ttgaggcgag atcttaaagg
     2461 tacggaagcc gggagaggtt ggctcgatac cacagacctt ctggctcaat aaggtaagcg
     2521 ggccaccgct ccaagcgtga ttgatcgtgc cgccaccgaa gccctcggct ccgatgcccc
     2581 atccctcgaa caaggttgtg tattcggcat aatccagcat acgggtgtaa cgttgcttca
     2641 tccgttccaa ggcaaacgcc ggctcgccca tctggaaaag ggcctctagg acatacttct
     2701 ccatataagg gctggcgtga tactcttttt taagtacctt cgtcagcgcc ggatacttat
     2761 ctttcgaggc cagcccggaa acaaccgcca tggcttggga gcgatcgtcc gtctcccctt
     2821 tatagccggg ggagcgatag gcggaacctg tccagaactt cgtgtcgaaa caacgttcta
     2881 tgctacgcat catccgggag atctcatcgg catccttatc cttgccgagt tgcagggcga
     2941 aggctcgctc cgctttcaag gccagataat accagcaatt ggtcaatacg cccatatcga
     3001 catgctcgcc ccagtcgccc cagctccaag cgccttgacg ctcgatcacc aagccactct
     3061 tatcgacttg ccaaacctcg tgcaggtaac ggcgcatccg gtcgtatatc accgggacga
     3121 aactactgtc ggcactataa taatattgcg tataaaaacc gtaccaaccg atagacgcca
     3181 acatctgtaa aggaagctcc ttatcccaat tacccgccgg aaccggagcg tagagcgttc
     3241 cgtcctcccg ctgccaattc attaattcat ggatgccttt tacggctagt ttctgcccgg
     3301 acggagaaag ggcgtagaaa gcctcgccta gctcattcac ctcgtcaccc caccattggg
     3361 cacgttcacg gtccggacag tccatataat tatcacgcat cgttatgtat aaggtgcggg
     3421 cagaacgttg ccaaagctcg tcgtagaacg ggtcgtcaca atggaaagag cccgcgaggt
     3481 ccgtgttgta accggtctca cggtatttca catccagcac cttcacgccc tcggggatga
     3541 tgtaatagac ctcatggccg ttcatccagc catagctttc gtattcctgc tcaccctcac
     3601 gagtgatata ttcggcacgt acattacgct cacttcctcc ctcgtaatta tccatccgga
     3661 tgtggatagt attcccggcc tccgcctcta cttttagata cggagtgatc tgggcattat
     3721 agggcaaacg acagaacaag gtatcgcctt tcaaggattc ccggacggat acataggata
     3781 acaggccgct gtttttccac tggggtatcg gacgttccac cagatccccg aaaggagctt
     3841 tccccgcctt accgacgcag accgcccccg gaagggaacc ttcgaaactc gtacggttcc
     3901 agtttgttat cgcttgacgg gcatcgaagc ggatattact ctccggcata cggtaattcg
     3961 ggaaaggggc ctcggtattt tgataagcct catacaaggc gcactgccag ctcgcgtcgg
     4021 agacgatctc cagtcccgga gcgatcgcct cgaataacaa agctgctttc ccactgttga
     4081 tatgactgaa accgtctttt ccgaaatgcc agagcaagat agcgatggtg ttcgagccct
     4141 ttgtcaggta aggggcgata tctaccggat cgtaataagt cccggaagga gaaggtcctc
     4201 ttttcaagcc accctcgaag ataaccagtt ggtcgttgat ccaaagccaa tacttggaat
     4261 cggcggcgat acgggcgatg agttggtccg ggacatccgt cacgccgaat gatttacggt
     4321 agatcaacca agtgttcgtg gcgctttggc aacgctcggt attgatccat tgggctttcc
     4381 aagggaagga ttcgggatga gatgaagctg tcgcctttat ccagccgaaa ggcaagagga
     4441 acaaaaagaa ggcaatgagt agcttattca taaatttaat ctttaaagtt caacagttta
     4501 taattatctg gttgtagaga cggggcgtgc cccgtctcat ctccccaaaa ggtaacttaa
     4561 agatactatt agccggtggg agacggggca cgccccgtct ctacaactaa gtatattaag
     4621 cgggatatgt aaatgtatgc gtaccggcgg atacggtctc ggtctgatcg cctaccacga
     4681 tatcggcgga gcaatcagcc ggaatcgtca cggtaagcat aaccttatcc ccttcccgtt
     4741 tccattcgct tgcgatacgg ccgcgtacgg aatggtactc acctttcgcc caatccagtt
     4801 ctttcacgaa atgaggagtg atacggatat gacggaagcc cggagccgag tcgtcatgat
     4861 tgataccggc cagctggttc atcatccaag cggagacatc tcccataaag acgtggttca
     4921 aggaagcgtc ggcaaacttc ggactaagtg tccacgtctc cggcaatgtg gagtaaccca
     4981 tcgtctctac ccaatatccc caagaaggtg cctcggtctt cgtgatcatc ttcatggcat
     5041 cctcgatata gccatatttc gtaagcatgg ccggaacggt cttactgcct aatagaccaa
     5101 aatccaagaa atagttattt cccgctacca cctcacgcag cttatccgcc acaagttgtt
     5161 cctttccttc cggtacaagt cccagataca aggccaaggc ttgcgccgtt tgggttcctt
     5221 cggcatacac actggtctcg gcgttgaaga acttctggtt gatcaaggat ttgagcgtat
     5281 tcgctttctc ttgataagga gcggcatcct tgcccagtaa agaggcgaag cgagccatca
     5341 acttataatc cagataatag taggcggtag aggtatattc attattcgtc gtagctttcc
     5401 aatacaccca gtcacccaag ccaaaaggca agtaaccgtc tttctctttc gtcttcaaat
     5461 aatccagata tcgcagcatc gtaggatata agcgttctat actgcgagac tctccataat
     5521 aatcatacaa ggcgttcggg atgataaaca tgacagcgtc ccaaaccgga cccggccact
     5581 cgccatatcc ccaaccgctg gaaggaatga taccggaaat ctcacccgcc tcacgctggt
     5641 tgtcgataat atcattcatc catttctcat aaagcgtgat accatcgaag cccagcaaac
     5701 cgaggtcgat cgcgatatgc gcatcggctg tccagccatt cttctcccgt tgcgggcaat
     5761 cggtcgggat actgtgcagg ttactgcggt aagcctgcat cgtagcctcc catatcttat
     5821 tcaatagagg attcgaacaa gcgaaggaac cggacggacg gacatcggta tgcataaaca
     5881 agccggtcaa gttctcttcc gttaaagtaa cgggacggct actctccacc tccacgtatt
     5941 ggaaaccgtg ataagagaag gaaggcatga agatctcctc ctctcccgta cctttcaagg
     6001 taaagacatc catctggaat acctcgtccg gtttgaccgg atgataatat acattgatat
     6061 tgccttgctc caagcgaccg tctttcttca acaactcacc atgttttaac gtgatacggg
     6121 ttcccgcctc acctttcacc ttcaagcggc aaaggccgga catgttcttc gggaaagaat
     6181 atacatataa ctgatcggag aaacgtttca tcgacacggg cctcacctct tccgtgatac
     6241 ggattcccgg catttgctgg gctaccaaca gaggtgccgg agcctgcgcc ggaagtgccg
     6301 cttcccattt actatcgtcg aaatgagcgg ttttccatcc ggcctcttcc agccgggcat
     6361 cgaatttatc gccgctgtat atattattat aggtataggc tccggtggaa atcttccaag
     6421 tcccgtccga accaatcacc tccgtcgtac catccgtata ggtaatacgc aactcacata
     6481 gcaggcgggg acgattccgc cagcgtgcct catgaaaatt ccagaccgcc acggactgct
     6541 cattgtacca gccgtttccc agaacagcgg ccacggcgtt gtcgccttgc ttcagcaaag
     6601 aggtaacatc atgcgtcacg tacaaaatac gtttatcgaa atgcgtatac cccgggtcca
     6661 gataattcgt tccgacccgc tcgccgttga tgaatagctc atgatacccg gcagatgcta
     6721 cgtatacacg ggcatccttc acttccttgc ctaccgggaa agacttgcgg aacagagggg
     6781 caggctcgaa ctccttatcc ttatgatcgg taatccaaga ggcggaccaa tccgagggat
     6841 cgaacttagc ggtctcgaaa gaagccgtct ccgaggtagc gcacggacgc ccttcaccat
     6901 cccataccgt aacattccag taataacggg tatgaggttt cagggccatt ccttccgcat
     6961 agggccgtaa gtcgtccgga ctcgtaccga tccgtacctc atagcgggaa gccttaaagc
     7021 cctcctcatt tccggagtat tcccatgtaa agcgaggaga cgaagtatcc aagccgatag
     7081 gctccgtaag gtattccgta cggagattcg taggtatcgt taattcatta ttgcttttac
     7141 aaccgcctaa taagagggcg gcgaaagcgt agatgcaaat agtttgtttc atatattcta
     7201 taattatata cattctacaa ctaagtataa gagctacggg gtaactcgta tctcttcagg
     7261 agcgttgata tggcttatca ccttaccgtc cgcacctttc tcatgccgga tctcaatcac
     7321 cccgtaaggc gtgggaaacg taccttccac ccattcgaga tctcccagat gtgggatgat
     7381 acgtaccgta cggcaacccg gttccaccac ttgtacgccc aatacgtact cgcttaacca
     7441 cgatgtggga cccgaagccc atccatggca caagctatgg cggaaacctt gatagcaata
     7501 cgccccataa tctccatgaa tatctttctt tccagcgggg accagctcat caatacgccc
     7561 tgcgtcagga agccattcca tattgaaatc ctcccaaaac gtcgtagcac ctacatccag
     7621 catagctccc caatacgtac ggatcacatc taacgcacct tggtaattac cagccaacgc
     7681 catcgcccgt agcatataat acccgtaaaa cgtagagaag cctttcgccc cgtccaccgc
     7741 caagcaacgc tcgttcgcct ccttagcatc catgataccc gccagagcca tcaaggcggc
     7801 ggcctgttta tccccaggcg taatccgatc tttctccgaa gggaaccggg atttcttccg
     7861 aagggaaaac ttaatagcct tggaagctac catacgacat tccgaagcca acgcatcctc
     7921 gcctaaaacg gtacataact cctctcccgc acgcatggct tgtatcatca gcgattgaag
     7981 gccggcatcg atagcgggtg tattctcact ggaaggccaa tccaagaaac ggttcccatc
     8041 cagtctctct tgtccgcttg ggtcaacctt cgagatcaag tgacgcaaca aagcagtcat
     8101 ataagagcgt tgctcttgca gatacgcaag attcccttgg taataatacc aatcccgctg
     8161 aatcaacaac caccagatcg agtacgaact gataccgttc atccaactag gcagcggcgt
     8221 aatatcccga atcaaatcca agctcttagg aaccacctca ttataaccga agacggtact
     8281 gaccgtcatt acctccggat gtaaatcccc cacccagacc agacgatccc gttttacgcc
     8341 gtcccataga tattcctgca tattcaagtg gaccgtgtat gcacctgtct tccagatccg
     8401 gttcaaccgc tcgtcattac aacggaaaga gcccagataa ggaatatccc gaaacgtgga
     8461 gatcgcacgg acctctttta attgcaactc cgtagaatca cccaatacat caatacgcac
     8521 gaaacggaaa ccggaattac cgatctcctg cacgcccagc caagggagcg ataccacgaa
     8581 atcccgcatc gcatgatcgt tgctcgcccc gttcgcgcca tctatctcgc acatagcctc
     8641 actaacggac tcgccgaaac gaacccgtac ggaaaccgga tcgtgagacg gcggcatacc
     8701 ggtcaccagc tgaaggccgc cttgcaactc cttcccgaaa tcaagcagca aagcgggatg
     8761 ttcggttggc gtacttttca acacacacaa ccgattattc gccaaatccg actgtccgtt
     8821 gcccggaaca agcaaatggt tcgctcccgt aattcgcgaa ctatcttgct gccagacaat
     8881 acggaccgga gcgatatact cccgtgtccg atggtctcgc tgctgggcga acaacttgaa
     8941 cgaaccgatc cctatgaata gaatgattaa tttctttcgc atacgctaga gtccaaaagc
     9001 cggaaccaag tcatccaatt gctgctccgt cataccttcc ggctcgtaac cggtcatgcg
     9061 ggcactaaaa tagatctggg cggatttact caacgtatcg atcgcatcga agcactcgat
     9121 caggtcctca ccgacggcaa ggataccgtg cttctcccag aacaccacgt cgtgctcctc
     9181 caactgacgg atcgtagcgt gcgccaacgc caaagtgccc ggtatctcgt aaggaacgat
     9241 accgacccct ttcggcacga taatccgaca ttccgggatc atacgccata acgtgcgggt
     9301 aatcttctcc gaatccaaga acggcttaca atgcgtcatg ccgataatat ccgtcggatg
     9361 cgtatgcaat accacccggt tatcccgtcc cttcgcacgc aagaaattgt gcatcaacaa
     9421 atgggaaggc aactcggaag tcggttggat cggttgctcc gctaggatat catacgattt
     9481 cccatcggcg gcgatacgga tcaaagagcc gttggcgaaa ggatctttcg ccacgtaacg
     9541 catccgtttt ccggtacccg tcacataaaa gacgtgcccg cataaggccg tcatcgcctc
     9601 ttgcaaggga atcgaggaaa ccaaagccgg caacgccttc tcctcctcgc tcaataaagt
     9661 agtcaggttc accgatatat tcccgccgtt tcgctcagcc caacccttgg tccacaaata
     9721 gccggcgacc tcggcgatac gatctatttc cgccatcagg cgttcattgt ttcttagtat
     9781 tatcatgtct attttaatta aactatattc ggatataata aggaaaggat caagatacac
     9841 atgccggtaa tcaataccac gatcgtccgg cgatccacgc ccttccattc ttttaataag
     9901 atgccccaga cattactgaa aataacattc aacgacatca ggatactcca cgagaaagcc
     9961 agcataaccg gggaatccga gaaatagctc tttcccatcc ccagtccgaa gaactgcgag
    10021 taccaaagca cgcctgccaa agcgcaaaat aagacattat tcagcaatgt acctcccgat
    10081 accgagaaat aatccttgcc cgtcccgttt ttcacgttct ggaaaataca atacacagcg
    10141 ttcgtacaaa agccgcccaa agtaaccaac agtatcacgg gattcaaggc gaacagatcg
    10201 ctagctcccg cctctctcgc tttcgccagc acctcgtttc ccgattccaa acccaaattg
    10261 aagcaggcgc tcatcacacc ggcaagcaag gctaccgcca agcccttagt caaggcaaaa
    10321 tccttcaccg ccgctttctt ctcctcctca ctcatattcc gggcccgcag gcttccggcg
    10381 taaccgatca cggcgatacc tgccaaggta atgcaaacac cggtcaacag gatcaatccg
    10441 gttccctcaa acagattcgt tccaccaaac aaagccggga agagcgtacc gaaaccggcg
    10501 catgtaccca aggcgatgct ctgtcccaaa gctacgccca gataacgcat actcaacccg
    10561 aaagtcaacc cgccgacgcc ccagagcatg ccatagataa ccgctcccaa gctacccggc
    10621 gaacgccata gttccagcaa ggtactccct tccggtaccg ccaacatcgc tccgagataa
    10681 gggaaaacca accaagcgaa gataccttgc accaaccaaa agctttccca actccaatcc
    10741 cggatcttat tgatcggcac gtacgagcta ctctgcccga aactgccgat cgcaatgatc
    10801 aacaacccga tcccgatctc tatcattgcc gtcttgaggt aacgtcggac tcatatttct
    10861 cgatctcagc gatataagac tctcctacgg ggaccccact ttgtagacaa tacatatccc
    10921 aaaccgcccc ccaaggcaga ctcttcgctt cctcctgcaa ggcaagacgc tggaaatact
    10981 taccctcatc ctcgtactgg cgaagcaagg cgatcggctc cagcaaagcg agcataaagg
    11041 ctttttgcgt ggcacggcta ccaatgacat aagcaccgat acgattgatg gtagcgtcga
    11101 aataatccaa accgatatgt acccggtcca aggcgtcgca acgcacgatc tcacgagcta
    11161 aatcctgtac atcgtcattc aagatcacga catgatcgct atcccaacgg atcggacgac
    11221 ttacgtgcaa catgatctcg ggcgtaaaca gcaataacga ggaaaccttg tcggcgatac
    11281 tttccgtcaa atggaaatgg ccggtgtcca aggtaacgat cttgttcttt ttcgccccgt
    11341 aacccaaata gaaatcatag gaacctaccg tataactttc cagaccgata ccgaagagtt
    11401 tcgcctcgat acaatctttc atccatttat attcggtagc gaatatctca tccagcgatt
    11461 cctccaagat acggcgataa cgtaagcggc tggccggtac ttccttgctc ccgtcatgta
    11521 tccaaaggtt catcatacaa ggatcgttct gggctttacc catctcatcg ctgatccagc
    11581 gacaacgctt cgtatgctcg atccagaagt tacggatatc atcgctgggg ttcgccaagg
    11641 tcaaatctcc gcttttaggg tgcgagaaag aggtactgtt gaagtctagc ttgaaatcat
    11701 tctctttcgc ccattgtatc cagctctcga aatgatgggg ttctacctcg tcacggtcta
    11761 ctttctcccc ttggaaatcc ccgtagatct catgcagact aagccgatga ttaccgggga
    11821 tataggattt cgccttcaat acatcccggc gcaactcgtc gatagtacgg gcacgtcccg
    11881 gataattgcc ggtcacttgt ataccaccgg tcaaggagcc gccttggttc tcgaaaccgc
    11941 ttacgtcatc ggcctgccag caatgcaggg atagggatat tttcttcata tcctctaaag
    12001 ctttacgaac gtctacacct acggccgcat aacgttctgc cgctacttca aatgcctgtt
    12061 gaattaaact gtcttttgtc atggtatgat gtttttaaat ttatatgatt tgaatgtgta
    12121 tcacctttcc ggataaaatt ccttgggagg gaatgcggtg gctatcagtc ttcgcatctc
    12181 ccaacaatcc gtcagtaatc ctgccgactt agcctgtatc aagcaatttc caatggctgt
    12241 cgcctcagac gggcctgcca atacgggaat accgatagcg ttggctgtca actgattcag
    12301 cagatcgttc cgagagccac cacctatcac atgcaatcgt tcaatcggat gtggcgacat
    12361 cgatttgagt atttccagca cctctttata acgattcgcc aagctataaa atatacaatg
    12421 tacataatcg gcgtccgaag cgggaacagc ctgtccggtt tcctcacaat aggccgtgat
    12481 ctcacgtagc atactctcag gattggcgaa acgaggatca tccggattga tcaaagaagt
    12541 aaattcgctc aactccgcca tccgaaccat atcatcgtac gaataatcca atccggaccg
    12601 cttccattgt tcccggcaac gttccaagat ccacatacct gtaatattct tcaaaaagcg
    12661 agtcgtaccc tcgatacccc cctcattcgt gaaattattc ttgaaagaga cctcgttgat
    12721 gatcggcttc tccacctcga tacccatcaa gctccaagta ccgctactca agtaagcgaa
    12781 attaggagaa gaagcaggaa cagcggctac cgccgacgcc gtatcgtgac cggccacggc
    12841 gattaccggg atttccccga ttcctgtctt acgggcgatc ggctcgctca accgcccgat
    12901 caacgtcccc ggcatcacca ccggacacat caaagtagga gatacaccta cggcctccaa
    12961 gagcttgtaa tcgaatttat gggtttccgg gttcaataat tgagacgtgg aagcgatcgt
    13021 atattcacat accatacgct ccgtcaacat ataagccaaa aggtccggta tgaataatat
    13081 cttttccgcc acttcctgcg gtataaacga gtcttgcccc gccctgaaaa gctggaacaa
    13141 gctattaaac ggcatcactt gaatacctgt ccgcttatag acctcttcct tgggaatccg
    13201 tttgaaaaag tcctcgggag cgccgtccgt ataaggatct cggtaagcac gaggtaagcc
    13261 caataaagag ccatccaaag ccacataccc aaaatccacc ccccatgtat ctattccgat
    13321 cgagtgcaac cggattcttt gccgggcgca tatcgtcaag ctttctataa gagaagtata
    13381 aagatgatag atatcccaat aaaaccgtcc gtgtaattcc accatcggat tcgggaaccg
    13441 atggatctct ttcatttcaa atttggcatc ctttaaggtc ccgagcacgg cccgtccact
    13501 ggtagcccct atatcaaagg ctagaaaatt atattccttc atggcttaac aaagttattt
    13561 gtttgacgaa agcaaaagta gaagcattat tgctatattt gcttacgaaa atgattttaa
    13621 acctttcaaa tctgacatga acgaactgcg gaatgattta ctacgttact tgacgatcag
    13681 cgctacggat gaggaatggg gaatcgtcgt cacgacggtc ggatatcaat tcatcccgcc
    13741 gggttgcgcc tatccacttt cccggcatcc ggagaagtat aatttcaagc ctcagaccgg
    13801 gcgcatcctg aatgagtatc aattggtata tataacgaaa ggtagcgggt acttttcctc
    13861 ccagtcttgt aaatcgcaaa agataaacgc agggacgatg atcctccttt tccccgggga
    13921 atggcatagt tattatccgg accgggaaac gggatgggat gagtattggg taggtttccg
    13981 gggcattcat atcgataaac gtgtggagaa gaaattcttt accaaggaag agccgctaca
    14041 ccggatcggg ctgagcgcta cgatcgtcgg actttatgag gatatactga agttcgcctc
    14101 ggaggagaaa tccggttacc aacagatgat ctccagtatc gtgcttcata tattaggctc
    14161 cgtatattat aaggaaaaga acaactcctt cacgaacacc tatgtcgtag ataaaatcaa
    14221 cgaggcacgt atattaatga aggagaacat cgaggaccca ttaagtccgg aagagatcgc
    14281 tgcccgtctt ggtttaggtt attcatggtt tcgccggatg tttaaagaat acaccggcgt
    14341 ctcccccgcc caatatcaat tacaacagaa gctccttcgt gcgaaagagc ttctgactag
    14401 cacccctttg acgatctccg agatcgccta tagcctgcat ttcgagaatg ccggccagtt
    14461 ctccacattc tttaagaaga aagaaggggt tacaccctcg gaattcaggg atcggacaca
    14521 ttgagataat attagaactc agccacgacc atcaccggga aatgatccga aggtgtatgt
    14581 ccgtataatg tgttcgttaa tacaccgtat ttatcaattt ggatactgtc ggttacccag
    14641 atataatcca gacgctcctc tgtcttgatc gtactatcat atccgtgata ggtacagacc
    14701 ggaccgaacg gggcttcctt ggtgatctta taagagtcgt tcaagaaacc gctatcattt
    14761 aaaatacgga tcggttcttc ggtaggaaac gcattgaaat cgcctgtcag gaatacaggc
    14821 tgattaccgg cgatactttt gatccgtgag atcattaagt tagaagattc cctacgggcc
    14881 acatctccct cgtactcata atgtacatta aagaaataaa attgtttatg gttcttcaag
    14941 tcctcaaact tcccccaagt acaaatccgg ttacagcaag taccatccca acctctaccg
    15001 ggtttctcgg gatgttccga taaccagaaa tcaccttgat ccaacacctt gaaccgatct
    15061 gaacgataaa atatggcgca gtgctctccg gcatcttttc catcatcccg tcctacacca
    15121 ataaaccggt agtcgcttaa ccgcaagata tcgtttaatt gatgcgtaaa tccttcttga
    15181 gtcccgaata aatcgaaacc ataaaaacgg attaagtcat tcaccatatc tttccggtga
    15241 aaccaagcgt tctccccatc ggatggagta tccatcctca aattaaaagt agcgatcttt
    15301 aagacctcct tatcttccgc ttttccataa gccatcgcca agaacagcaa tgacacgaat
    15361 ataattaact ttttcatgat tcattctttt tttagttacc aacccggatt ttgtgtcaag
    15421 ttcggattca tgataatatc caagtccgga ataggatata gataatgctt atcctcccat
    15481 acccggggaa tattattcaa ccaagtcaat tctcctttcg tattccctga taaacgctgc
    15541 ggatttacct taccggcctt catctcggaa acgaccacgt aggtcactcc cgatatcggg
    15601 ttctccacgt tctcattcat cgtaaaacat acatccaaga taccatcttc atttaaatcc
    15661 atcggcttat ccaattccgg gacatagaaa ccattccaag gcattgtcat cagattccct
    15721 tttttccaac gtaacaaatc actgaaacgc aaaccctcga ataccaattc gatacctctc
    15781 tcacgacgga tctccagcaa actgggatct gttatttccg ggaaataatt cgcttgcagg
    15841 taaggatcag cctttgtcgg tctagctgtc aaacctcctg ttatccccgc tctaccccgt
    15901 aaagcaccga tcgttttttc ccaatccgca tccgtgaaga ctccaagctc cgctttcgct
    15961 tccgcatagt tcaataatac ctcggcgaaa cgaatcaaag gaatcgaatt atcattattc
    16021 gcaccgctat cataaaacac atcatccagg caatacttaa taggttgata accggtatag
    16081 gtataagaga agatcggagg agcgggcgtt tgcacccccc catcaatacg cttataatcc
    16141 cccatacgga tggtttgttg caaacgttta tcacgattct tcacctcatc cataaagacc
    16201 atggtcttat atccctcctt gtccgtaaaa ggagtaccgt cctccatcaa ataagtattc
    16261 acgaacgtac ggatcaaatt cagacgggga ccatatgtag cgcttgtcca ataccagtta
    16321 gcgtcattca atacgctcaa ggacttatca caaacagcgg caagcataac ctccgtagtc
    16381 accggcttca cactgataaa caaatcccgg tacgatttcg tcgtaccgtt tgccgtatac
    16441 aatttaaaac cagagttagc gatcacatcc tctgccgctt taaccgcctc gttcagccaa
    16501 gcattcgccg actctttcag cccatattcc gtatgatact tacggaacgt cccctcgaac
    16561 aggcatactc tcgacttgaa agcctgagct acatacttcg tgatcaagga actggtctga
    16621 tcactcgtca aggtaatatg ctcgcaagcg aaatccaaat cagccaagac cgaatccatc
    16681 accaaggttc tcgaatccct tgccgcatac agatcggggt catccacctc catcgcctta
    16741 ttgatccaag gcacgtcgcc aaagcgtttc accttatcaa agtagaacca agcacggaag
    16801 aaacgagcta aacctatata attcatccta acgctttccg atacccgtgg gtccgtacaa
    16861 ttctggataa agtaattgat gttccgaagc ttttcccaat cccagccatc gctctgttga
    16921 ggaccatagg catccgccaa tataaaatta ggaaccaacg ccctcgccgc ataatcacac
    16981 atattatccg cttggtgagc ggccgatgga gtcggtaaaa tctcatagaa cgagttcgca
    17041 tataattcca atccattctc cgtactgaaa accggttcct tggaaacctc tgaaacagga
    17101 acctcatcca aatcgcaaga gaacaaacct atcacactga tgatatatat taatgtcttt
    17161 ttcatactat agcacttttt agaatgtaac tgacaaacca aaactaacac tcttcaatat
    17221 cggatagcta tatccattac ccgacgtacc ctccgttaaa tcccggtcag aacctctgac
    17281 cgcctcaacg tctaagtctt tagaatattt atagaaagga gaccaactcc aaagattctc
    17341 gcccgagacg tataccttgg cattctgcat ccttagtttc gagataaagc tcttcggcaa
    17401 agtataccct aactgaatat tcttcatacg tatataggcg atattctgta agtaacgggt
    17461 ttgtttcaag ttcaactcgg cataaggctc ctcagaggag tatcctctca aacgggggaa
    17521 ataggtattc ggattctcct ccgtccagat attccccaaa tgagatttag gcatatcatt
    17581 atacggacga ttatacatac cccagaaata agaggcttcc gatcccggcc accaatcttg
    17641 tttacctaca ccttggaaga aagcggagac gaagaagtta ttccaatcac cgctcaaatt
    17701 gataccatag atgaaacgag gctcgctatt accgattatc ttctggtcac ccggattatc
    17761 caccgtattg tttccataat caatcacgcc atcgccgttc aagtccttga acttgatatc
    17821 gcccggaagc cattgtccag ccgtagcacc cgcgtagaaa tagggttgtt tagcgtggct
    17881 atcgatatca gcttgcgagg taaagaaacc ttcagtctcg tatccccaga tctcacctac
    17941 cttcataccc tcgtaatagt aatcatcgcc cagtttcttt tccgggttat tgtatttatc
    18001 aatcgttgac tggtaatcgg cgagcgtgaa acgaacctcg taattgaacg gtttacttgc
    18061 caactggaat tgatcccgcc aagagacact caactcaaaa ccttttgtcg taagatccgc
    18121 atagttacct ttcggcacat ccgtaccgaa caccgccggc aatgacatac ccaccgtaaa
    18181 catatcggtt gttttccgtt gatagatatc gcccgagaat tgcaaacggt tcgataggaa
    18241 agcaaagtcc agaccaaggt tcaaggtcgt agatttctcc caagtcaagc ccaacggaat
    18301 aaccgccggc tggtccgtat actgcggacg tatgccattc aacaccaaac tggattgctt
    18361 gatcttaaat aactcttgga atgagtacgg atcaatatta ccattaccca aggaaccata
    18421 agaggcacgt accttcagat tcgagaagat ttcctcggga accttccaga acggctcttg
    18481 cgaaaccctc caacccgcag agaccgatgg gaagaacgca tattgagaat ccgacgggaa
    18541 tttggaagaa ccatctaacc gaccattcac ttccaataga taacgatcat taaagacata
    18601 attcaaacgg aagaaacctc cggatatacg ccatttggaa taaccaccct cggtattaat
    18661 cgtttgtccc aaggccatat tcaaatcctc ggcatcatca aagatcaatc cgtttctcaa
    18721 tacctttaca ttcttcatac gggattcctc gtagttatat cctaccatcg ccttgaaata
    18781 atgcacttct ttaaaggtat cctcgtattc tccgtaaata ttgctagcca gataactagt
    18841 cgtcttattc gtattctgga tatcattctt ggaagaacct acgtactcaa tcacacccgg
    18901 acggcggctg aacggcaccg gtacccggat ctgggtttgg tcgttgtcat tgttctggaa
    18961 cgtaaaatca cctttgatac gcaatttatc cttcaagaaa ctagccgtag cgctcaccgt
    19021 attcttcaag atcctttgct cggtatcgat accattcttt ccgtaccaga aatcaccaac
    19081 cgtataagcg gcagagtgcg tcaaggtacc atccgggtta aacatcggag ccaaaatatg
    19141 cccctcatcc gcgatattac gccagatacc gccaccttca cctacattca acggattatg
    19201 ataagtcatg ctggaatact ccaaattgtc ctccaccttc aaccaatcaa atacctgcac
    19261 cgctcctttc gcacgcatat tgaacaactt atagtcgtcc gtattatatc ggaacaatcc
    19321 atcttgccca taataacggc ccgttacata gaaactggtc ttgccgctac ttccggacac
    19381 ggaaatatta tgatccgtag cgaacgtaga tttcttatac aattccttgt accaatccgt
    19441 atttccataa tatacataat ccccattcgg accgatctct acctccggta atcccgagat
    19501 gccggaacga cgctccagtt cctccagata ctcctgagag aatttcaagg tcttattaat
    19561 gttctgtgga gtttgggaat aatcgtaata agcgctccac gcctcattaa agtatttagc
    19621 gtatgtatat ccatcggtaa cgacatccgg taccttcgtc ggagatttca tcgtaaaatt
    19681 acccgagtac gtcacggaag tcttgtcctt ggacggattc ttcgtcgaga ttaatacgac
    19741 accaaatgcg cctctcgcgc cgtaaatggc agccgaagcc gcatccttca agacagatac
    19801 actggcgata tcattcgggt tcaacatact gggatcaccc tccacgccat cgatcaatat
    19861 caaggcgcta cccttttgtc cgatagaggt cgtaccacgt atattatatt ccgccgtacg
    19921 atttggttta ccatctgtca tcgagatatt cagattaggg atcgtacctt gaagcgcttg
    19981 ggtaacgttt gagatggaac ggttatcgaa cacctcactc gtcacttgtt ccaccgcacc
    20041 cgtcagattc accttcttct gggtaccgta accaaccacg actacttcat ccaatttctg
    20101 ggtatcctca cggatcgtca cggtcagctc gctcttccct ttaacagcga tatcctgagg
    20161 cataaaaccg atataagaga cttgcaagat atcattgtcc gaagcctcca ccgagaaatt
    20221 tccatccatg tccgttatgg taccgttcgt cgtacctttc accacgacat tcgccccgat
    20281 taccggatca cccaaaggat ctagtatcgt accggttatc ttgcgggaag gtttaccggc
    20341 tgacgcactt gcattttgtc tcggaaacaa agcgatctgc ttactggtga tctcaaaaga
    20401 gaggtccgtg gtccttagca ttgaatttaa ggcagactct ataggctgat tcgagacgtt
    20461 caaacttacc ttttgagtca agtctatctt gttaccgtca taaaagaacg tataaccgct
    20521 agcgacctca atctcatgga tcgcctcttt caacggtagg ttcgaaaatg aaactgatat
    20581 cttcttgtcg acggcttcaa cagctaacaa acgtaaagaa aagaatagaa gaaagaatat
    20641 cgcatacaaa caatttcttc ctttcacaaa ttgtctttta ttattcatat atttgcgaag
    20701 tatttaaagt taacatcctt acagctttag acaaacggcc aaatttgaac aagctgtaat
    20761 tagattttaa tttggattag ggatttgtcc ccgaaaggct taagttaccg cttaagcctt
    20821 ttttgttgtc ttatgtcatt gggattatct cataggcatt actttttaga aggttcaaca
    20881 tgcattattt gtacgtgatc atcctcgtcg aacgtataag cgatcgggtt tatgcgcgac
    20941 atgatccgta agatcacttc cagtgactca tccttgattg tgaacgtata ggcttgtgaa
    21001 tccgggatgg taggatctac ctcgatctta acattatacc atttctccag ataacgagtt
    21061 atgtaccgta acgacttcgc ctcaaaccgc acactctcgc ttgcccagaa agactcgtaa
    21121 aacatatcgg cggaggttat attcaaggtc ttatcccttt tattcaaagc ggcgatctcc
    21181 cccggataca gataagcctc cttacctccg gcctccaaag agactgaacc ccggaaaagg
    21241 gtcacccgaa tgttttcttc ctttggataa gagttcacgt taaagcaggt accatgtacc
    21301 tttactttca cctccgaggc caagaccacg aaaggatgcc ggttgtcttt cgtcacgtca
    21361 aacagggcct cgccgttcaa agccacttcc cggttctcca tgaaatctgc cgcatactcc
    21421 aaggtagaac cggagttcaa ccaaacaacg ctgctatccg gcaatacgat cctcgactta
    21481 ccgcttaaag cggaataaga caacttattg gaataaacgg cccggtctcc tccagtatac
    21541 aagaaagaga aggtcaacga aatgatcaat aatatggaag ccgcggctac cgccatacgg
    21601 aatttccaga tagagacgac tttaggagcc ttgttctctt gggacatacg actttccagt
    21661 tgttgccaat aaaaagcggt atccggcgta taggatgaag cctcctcccg gatctctctc
    21721 cataatccct ctagttcttg atataaatga gcattccctt ccccttgaag ccattcctcg
    21781 aacaacttct cacctctctc atcttgttca tccttcagac gagatataat taattgccat
    21841 ggtatatgtt tattcatgaa gtgccatttt ctagtgtgac acatcaaatg acgataaccc
    21901 tacatagttt tcattatttt ttttaatctt gtggaaataa aatcaccata agtagtgata
    21961 ggcatccccc aaataggccc ggatctgttt taacgctctg gaaatatgcc cttccacggc
    22021 tttaacgctt atattcattt gctccgctat ctccttattt gaaaggttgt ccatacggct
    22081 cttattgaat acatcacggc atttcggggg aagggagaaa atagcctcat gaatcaggcg
    22141 ttgcaactct tgagtttcta atgtctcgtc attctcgaaa cgttccaaag aggaaaaatc
    22201 gtcctttgag ataaaacgct cgttatctct taggtaattc aaggccctat tccgtgcgga
    22261 ctggaataga taggctttca acgtgatctg gatttgtaag gtctcccgtc tttcccaaaa
    22321 gctggcaaag atatcgacta cgatatcctc ggcggctccc ggtttcttca tatataaatg
    22381 tacgaagcgg cataaaggag tgaaatataa ctcaaacaga tgtttaaaag ccagtctatc
    22441 accagctttt atcagtttta gaataaacaa atcgtctata gttttatcca ttattccatc
    22501 tcccttagcg tcaagatatt tgcaaacata gacataaaaa atcaaatggc aataactcga
    22561 taaactttaa atagattcat tctacttgat cgagcctcct tgagagaatc gcatctattt
    22621 gtaatatccc ggttattttc cccagatata ttttgcttta atcctagtaa atacatattt
    22681 ttacttcaaa ttaaaatttt aagttatgag gatcacttat cttttactct ctcttgtact
    22741 ttgtctctgt ccggtcatgc aggcgcaaaa tacgacgaat caatttatga aacaggcaca
    22801 aagcagcctg gaaaaaaaag actacaccaa agctcgttat ctttttttac aagcttacaa
    22861 gagcttatcc caacaaggtg attacaaaca ggcaatcgat gccggtacgc aggcggctta
    22921 tctatattat tgcgagaatt attaccaaga ggcattcgat ctttgccgcc agatgaacca
    22981 attcatctta accgaggaac tgaagttgca aaaatcgctc tatgagcaac gcttccaagt
    23041 aacgaaagag cggttggaaa tgtatattaa gctaaagaac gccgcccaag cgcaagttca
    23101 actcaataca ttagataatc tggccagcca agcgggtgat gagaagttat cgaacaattt
    23161 attatatacc caagcgggtt attattatac gttcgggcaa aacgagcagg gggacgctgc
    23221 tttccagaaa ctgatcaacc agtataagga gaaaaaagaa tacgacaagg tgaacgattg
    23281 ctaccggaac ctgatctcta tcgctcgtaa ggcaaacaac gccccactga tggaacgtac
    23341 ctacgacaaa tacatcgtat ggacggattc cgtaaaggct cttacggcag aggataagct
    23401 aggggcatta caacaaaaat acgatcagag cctacagaca atacaggaga aagacgataa
    23461 attgtctgtt aagcaatata tgattgttgg acttatcaca ttcgtggtaa tccttatagc
    23521 cgccttactt ttcttaggat tccttttgct gcgcttcatc gtgctgaaca agaaattaaa
    23581 gaaaatcatc cagacgacaa atgagcatag cgaacaacaa gcccaattca tccaaaacat
    23641 atcggttcag atggagccta ccttgaacaa gcttagcgca tccgccaagg aattacaggc
    23701 ggtagctccg aagcaggccg aggatgtatg gacacgggta gaggctttga aacagtttac
    23761 ggttcatatc caagagcttt cctccttgga gaatacgttg atggaaccgt atgaggttag
    23821 ttcttttaat gtaggaaact tcagtaagaa aatcgtggag aaggttaaag gggatattca
    23881 accggaggtc aatctcgtaa cagacgtgcc ccaattggag attaagacaa acgccgagca
    23941 tctggaacaa gtcttattgc atttgttaaa gaatgccgca ttatatactt ccagcggtaa
    24001 catccgtctg gaatttaaac ggaaaggcgc tcatgtttgc caatttatca ttaccgataa
    24061 tggtacaggc ataccggatg atctaaaaga gaacttattc aagccattca atgaggcgaa
    24121 ggatctagcg caaggcgatg gtttgggatt acccatctgc gcactgatgg ctagcaaatt
    24181 aaacggaacc ctatctatcg ataaggaata taagaaggga tgccggttcg tcttggtatt
    24241 gcagatataa aatagactca ccttgtttgt ctttttaccg cgatgcggat gcagtgacgc
    24301 tgcaatccgg gttgcagtaa cactgcatcc acatcgcggt atcactgcaa cccgggttgc
    24361 ggtagcttat tccggcaaat gcttccgtaa gaactcaatc cagttaccag aggcgatacg
    24421 gttgatagca tcgtccgtaa agccacggta ttgaaggatc gggaatatct tttggagatc
    24481 ggcgatcgtt actaggtcat acgggcattg ctccgtaccg aaagcaccat ccagatcact
    24541 gccgatagcc acatggttcg catttccggc caattggcag acatgatcga tattgttcgc
    24601 cataatctcc ataccacagt tcatgcctct tggagtagac tcgcctcgca cccagttcgg
    24661 taccatcatc caagcgtcta gggcgatacc gatcacggcg tcacgctcta tcaacgcctt
    24721 gatcatctcg tcgctaaact gacggttgtg atctacgaag gcccgacagt tgttatggct
    24781 cgcccaaatc ggtcccttat acaaatccaa cgcatcccag aaagcctcat cacataaatg
    24841 ggtcacgtca agaatcatac ccaagcgatc catggtacgc aacaactctt tccccatggc
    24901 attcagatga ccggtagaat ccgtaccgtt ggcatacctt ccggggccgt aatgtgccgg
    24961 gccaaccgcc ctcaagccat aagcatacgc cctttccaca tgattcaccg tgatgaacga
    25021 gtcggcgccc tcgatactta atacataacc gatcggcttc ttgtcggcgg gttcaccgtc
    25081 tttccaaaga gccagatgcg cttccaaggc cttcttatcc cggatcatg
//
LOCUS       DBMDTB010000060        24885 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_701_length_24885_cov_11.675638, whole genome shotgun sequence.
ACCESSION   DBMDTB010000060 DBMDTB010000000
VERSION     DBMDTB010000060.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 24885)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 24885)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24885
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_701_length_24885_cov_11.675638"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..1065
                     /locus_tag="ACZPB4_10640"
     CDS             <1..1065
                     /locus_tag="ACZPB4_10640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005247 - voltage-gated chloride channel
                     activity [Evidence IEA];
                     GO_process: GO:0006821 - chloride transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HIR1098702.1"
                     /translation="VFCGLVSLYFTRVMNKVEGMYRKLGTYWKKFMLGGVMLSILIFL
                     FPPLYGEGYDTIGSLLNGQFSHIMDKSLFYDLNDTYFGVLIFLTLILLTKVFASSATN
                     AGGGCGGIFAPSLYLGCIAGFIFAHTSNYFPFTMYISEKNFALLGMAGIMSGVMHAPL
                     TGVFLIAELTGGYDLFLPLMIVSISSYITILMFEPHSIYSMRLAQKGELLTHHKDRAV
                     LTLLRADSVIEKDFQMVSPEMTLGDMVKVISRSGRNTFPVVDERGVLLGIVLLDNIRN
                     IMFRPELYNRFHVSKFMVSAPAKIVINTPMDQIMQTFDDTKAWNLPVVDENGHYIGFM
                     SKSKIFNSYREVLVDNFSGD"
     gene            1096..2070
                     /gene="fmt"
                     /locus_tag="ACZPB4_10645"
     CDS             1096..2070
                     /gene="fmt"
                     /locus_tag="ACZPB4_10645"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0071951 - conversion of methionyl-tRNA to
                     N-formyl-methionyl-tRNA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HIR1098703.1"
                     /translation="MKKEDLRIVYMGTPDFAVESLRALVEGGYNVVGVITMPDKPMGR
                     HGSVLQPSAVKQYAVSVGLPVLQPEKLKDEAFLEELRALRADLQIVVAFRMLPEVVWN
                     MPRLGTFNLHASLLPQYRGAAPINWAVINGDTETGVTTFFLTHEIDTGKIIRQKHLPI
                     ADTDDVETVHDALMAMGAGLVTETVDLLLDGKTDAIPQEEFYKDAAELRPAPKIFKDT
                     CHIDWNQPVKKIYDFVRGLSPYPAAWTELISADGKRMVLKVYQTEKRPATHNFPVGSI
                     HTDHKSYIDVAVKDGFLRLHSLQLAGKKRMNITDFLNGFKQIAEYTVG"
     gene            2070..2444
                     /locus_tag="ACZPB4_10650"
     CDS             2070..2444
                     /locus_tag="ACZPB4_10650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HIR1098704.1"
                     /translation="MNGTRRIIYITLGTFFLILGAIGIFVPLLPTTPFWLLTCWFYVR
                     SSERLYNRVMSNRYFGPHIKGFVEDKAIPLRSKIITIAIMWLSTIITSLLLVGYWWVK
                     ALLGLISIGVSWHILSYPTKKE"
     gene            complement(2516..3982)
                     /locus_tag="ACZPB4_10655"
     CDS             complement(2516..3982)
                     /locus_tag="ACZPB4_10655"
                     /EC_number="1.11.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004096 - catalase activity [Evidence
                     IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="catalase"
                     /protein_id="HIR1098705.1"
                     /translation="MEDKKLTAANGRPVADNQNVQTVGPRGPMVLQDPWFIEKLAHFD
                     REVIPERRMHAKGSGAFGTFTVTHDITKYTKAAIFSEVGKKTDCFVRFSTVAGERGAA
                     DAERDIRGFAMKFYTEEGNWDLVGNNTPVFFLRDPLKFPDLNHAVKRDPKTNLRSEDN
                     NWDFWTLLPEALHQVTITMSSRGIPYSYRHMHGFGSHTYSFINNKNERIWVKFHLRTL
                     QGIKNLSDEEAAAIIAKDRESHQRDLFESIERGDFPKWKFQIQLMTEEQAETYPINPF
                     DLTKVWPHKDFPLMDVGILELNRNPENYFQDVEQAAFNPMNTVEGIGFSPDKMLQGRL
                     FSYGDAQRYRLGVNLEQIPVNKPRCPFHAYHRDGTMRVDGNYGAAKGYEPNSFGEWKD
                     SPEKKEPPLKVHGDVYNYNEREYDDDYYSQPGALFRLIPPEEQQLLFGNTARAMGNAQ
                     LFIKQRHVRNCYKADPAYGKGVAEALGISLEEALKEDR"
     gene            4970..5371
                     /locus_tag="ACZPB4_10660"
     CDS             4970..5371
                     /locus_tag="ACZPB4_10660"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HIR1098706.1"
                     /translation="MSRKEEYKEKNLLYLDEIASEEGTQTLPCGILYKVIQAGTGKVS
                     PNRENVVSVHYKGTLINGREFDNSWKRSCPEAFRLNQVIEGWQLALQEMRVGDRWIIY
                     IPYSLGYGNRASGPIPAFSTLIFEVELLGIA"
     gene            complement(5480..8617)
                     /locus_tag="ACZPB4_10665"
     CDS             complement(5480..8617)
                     /locus_tag="ACZPB4_10665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0042908 - xenobiotic transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HIR1098707.1"
                     /translation="MVKFFINRPIFATVLALIIVVAGLVTLNILPIAQYPEITPPTVQ
                     VSAVYPGADAQTVAQTVGLPIEQQVNGVDGMLYMSSNSSSSGAYSLTITFAVGTDIDM
                     ATVMVQNRVSIAQSSLPEPVIVQGITTRKQSSNIVMMLTLSSKDSIYDGLYLSNYATL
                     NMIDQLTRLPGVGSVQVMGAGNYSMRIWLDPEAMRIRNLTPDMVYQAISTQNAQVSAG
                     YVGQPILRADNPYQYTLTVKGRLTTPDEFGNIVLKTGQGGKILRLKDIARIELGSSSY
                     NVVSKLSGQPTAAIAIYQLPGSNSLDVSKVVKAKMKELGSSLPEGVEYKVTLDTTEVI
                     DASIHEVLITFLETTLLVVLVIFLFLQNFRAVVIPFITIPVSLIGTLAVMAALGFSIN
                     TLTLFGLILAIAVVVDDAIVVVENSTRLLDTGKYTAHEAVSKAMDEIVGPIVGVVLVL
                     LAVFIPTTFISGISGQLYKQFALTIAAATVLSGFNSLTLTPSLCALFLEKNTEEPKFF
                     LFKGFNKVYGKTQKMYDSIVERMLKRPGAAMIVYGIITAVAVILFMRWPTTFIPEEDD
                     GYFLIVSQLPPAASLNRTEAVTKQIDEILKTYPEVKSFISVSGFSVMGGGEQSNTATF
                     FVILKNWNERKGKEHTAEAVTNRFNREASAIQEAQVFGMVPPAIPGLGASGGLQLQLE
                     DRKNLGPTEMQHAVETLLASYRSKPQLLNLSCMYQANTPQYLLKIDRDKVQMLGLQLN
                     QVFSTLSYYMGAAYVNDFVEFGRIYQVKIEANGEAQKVIDDVLRLSLANSKGEMVPFS
                     SFIELDEQLGLDQINLYNMYSSAAITCIANPKYSSGEAILAMEELIQEQLGDNFGYEW
                     TSVAYQETKAGSTTVIIFAMALLVAFLVLSAQYESWTSPLAAIMGLPIALLGAIIGCW
                     VMGVPVSVYTQIGIILLIALSAKNGILIVEFARDFRKEGNPIRDSALEAGHVRLRPIL
                     MTSFAFVLGVMPLLFATGAGAASRISLGAAVVFGMAINTIFATMFIPNFYELMQTIQE
                     KWLDKGKKTDDTPKQ"
     gene            complement(8625..9740)
                     /locus_tag="ACZPB4_10670"
     CDS             complement(8625..9740)
                     /locus_tag="ACZPB4_10670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HIR1098708.1"
                     /translation="MKTFVYIGIIGASALLLASCKGKSKPMETPVPSISVSTPIVRDI
                     TLTKEYPGYLSSQLKVDLVARVNGYLRTSYLKAGSRVKKGDLIFVIEPDTYQDNVTQA
                     EASVKTSKAQLEYARSNYERMKEAAKSGAVSQIQVIQAEATVSESEAAVKNAEAELNT
                     ARTNLSYCYIRAPFDGAVTRASYDIGNYINGAVQPVTLATLYKDDLMFANFNIEDNQF
                     MKMMLEAARNDSTVKLPTEILVSIGKDGGNAYTGRLDYLSPNIDLSTGTLNVRANLDN
                     PKHVLKSGLYVTITLPYAEQPDAVLVRDASIGTDQLGKYLYIVNDSNVVRYRPIEVGQ
                     LVDDTLRQVTAGIGPKDPYVTSALLKVRDGMPIKPIK"
     gene            complement(9810..11216)
                     /locus_tag="ACZPB4_10675"
     CDS             complement(9810..11216)
                     /locus_tag="ACZPB4_10675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0015288 - porin activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux transporter outer membrane subunit"
                     /protein_id="HIR1098709.1"
                     /translation="MHKHLRLTCYALLCLLVPIGVMAQTEHTYLDRALPGSWSEEGSD
                     FQQTLPVEDNWWRNFKDPLLDSLIEVAVKQNYSVQMAMDRIAMAKANLRSAQGSYSPT
                     LGLSAGWTRQQSSGNINQVPKAITQYSSATVDMNWEVDVFGSIRNRVKAEKENFAASK
                     EEYNAAMVSLCAQVASSYINMRELQQEVKVAQQNCRSQQTVVQITQKRYETGLVSKLD
                     VAQAQSVYYSTKASLPMLEAGIIQYANSLAILLGLYPSDLQKIMETDASLPEYIEPVG
                     VGLPANLLLRRPDVRAAERQVNALAASLGASKSDWWPKVFVKGSIGFASHDFDKLANH
                     NSLTYEIAPTLTWNFFQGTQKIQATRLAKAQLDESIRQFNQTVLTSVQEVDNAMSSYK
                     NSIKQIVALREVVNQGKQTLDLSLDLYKQGLTPFQNVLDAQRSLLTYQNQLTQAQGSS
                     LLNLIQLYQSLGGGWNPM"
     gene            11312..11791
                     /locus_tag="ACZPB4_10680"
     CDS             11312..11791
                     /locus_tag="ACZPB4_10680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF456 domain-containing protein"
                     /protein_id="HIR1098710.1"
                     /translation="MDILLVILGVICLLVGLAGCFLPVLPGPPVAYLALWLLHFTGYA
                     EFTVTELVVWGLLVVLAQAMDYVTPMLGTKYSGGSKWGNWGCAVGTVAGIFVFPPWGI
                     LLGPFVGAFVGELLGGKASGDALKAGFGAFAGFLLSVVLKVTLCGYFIYSFVRGIIN"
     gene            11816..12709
                     /locus_tag="ACZPB4_10685"
     CDS             11816..12709
                     /locus_tag="ACZPB4_10685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-isomer specific 2-hydroxyacid dehydrogenase
                     family protein"
                     /protein_id="HIR1098711.1"
                     /translation="MFEKIVVVDSTGLNTWGVERLKELGKEVVFYTGIPETDEEIVNR
                     IGDADCVLVSYNTQIRRNVIEACPNIKYIGMCCTLYSESSANVDIAAARERGITVLGI
                     RDYGDEGVVEYVISELVRLLHGFGGKQWKHKAYELGGQKVGIVGLGRTGRMIADALRF
                     LGAEVYYFSRTRKPDAEAAGIAYLPLRELLPEVDILCTCLPRNTILLGAGEFRLFGNL
                     KILINTSVGPTFRVPDLQRWLSAHKRNFFLCDEVGIGNYADTLTQFDNVIYTPKVSGH
                     SEQCMERLSQKVIANIESYQN"
     gene            complement(12783..15068)
                     /locus_tag="ACZPB4_10690"
     CDS             complement(12783..15068)
                     /locus_tag="ACZPB4_10690"
                     /EC_number="1.1.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004470 - malic enzyme activity [Evidence
                     IEA];
                     GO_function: GO:0004471 - malate dehydrogenase
                     (decarboxylating) (NAD+) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent malic enzyme"
                     /protein_id="HIR1098712.1"
                     /translation="MAKITKEEALRYHAEGKPGKIEVIPTKPHSTQTDLSLAYSPGVA
                     EPCLEIEKNPLDAYEYTAKGNLVAVISNGTAVLGLGDIGPLAGKPVMEGKGLLFKIFA
                     GIDVFDIEVNEKDPEKFIQTVKAISPTFGGINLEDIKAPECFEIETRLKNELDIPVMH
                     DDQHGTAIISGAGLINALEIAGKKIEDVKIVVNGAGAASISCTKLYVMLGARKENIVM
                     CDSKGVISTSRPDLNAAKREFATDRPIKTLQEAVVGADVFLGLSVANVLTKEMVRSMN
                     ADPIVFALANPNPEISYADAMASRDDIIFATGRSDYPNQINNVLGFPYIFRGALDTHA
                     KAINEEMKRAAVYAIADLAKEPVPDVVNAAYKLKRTTFGRDYILPKALDPRLLTRVSC
                     AVAKAAIDSGVSRKTITDWEGYANHLREMMGYDNKLLRSFTDMAKANPKRVVFAEANH
                     VNMLKAAAEAKAEGICFPILLGNEERLAKIAAEENISLDGIEIVNLRHDRETERRHRY
                     ARILTDKKAREGVTYSEACEKMVDRNAFGMMMVATGDADAFVTGVYSRYSEVTKMAEQ
                     IIGIRPSYKHFGALNILTCKKGTFFMADTLINRHPSAEVLIDIARLTHDAVKFFAHEP
                     VMAMLSYSNFGADKQGSPLKVHEAIDFLHKTYPDMVVDGEMQVNFALDKKLRDDMYPF
                     NKLKGQDVNTLIFPNLSSANSAYKLLDTLGITETIGPIQMGLNKPIHFTDVESSTRDI
                     VNLTTVAVVDAIVQEQIEKEG"
     gene            15454..18882
                     /locus_tag="ACZPB4_10695"
     CDS             15454..18882
                     /locus_tag="ACZPB4_10695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SusC/RagA family TonB-linked outer membrane
                     protein"
                     /protein_id="HIR1098713.1"
                     /translation="MLKNFKPVNLILVVGAMALPVSAYADLVPEKLDVSISLQSGKVT
                     GVVEDNFGPVAGASVVVKGTTNGTITDMNGNFSLEGVNNGDLIQISFIGYMTQELIYK
                     GQAISVKLAEDTQKLDEVVVTALGMKRSEKSLGYAMKEIKGDELNANLINPVAALQGK
                     VAGLEISGSDGGMFGSSKVQIRSASTLGKNNQPIYVIDGVILDNSIKEGNPDWDSNPN
                     DYGNELKNLNPDDFESVSVLKGAAATALYGSRGLNGAIVITTKSGKSGQGLGINISQS
                     FGMDVITQTPSFQNEFGNGIIAGNVDYGDKNANGDYYIYDNFGQYPTNANGQFSLMND
                     QGMSWGPAFDGREIQYYDGSTRAYSPVKNNFHKAYQKGFSSNTNVAISGGNEKTTFYT
                     SLSYKHVDGTTPNNSFDRISFLGKASHMFHPKIKLEASMSFANSMPKNSPINIGENFA
                     SGVWGRSYDPSTAKDKYKGVHGGLASSSYGDEYGNMPGIGTWWSVYENDYRQKEISVR
                     PVVKLNIDLLDWLKFNVKGSYNYYYTRFENKQPGSGYANEGGYYGIGQTTKEQTNLNA
                     NFMFNKTFGDFTVNGFLHGEFYENFQQAQSMNTNGGLIAPNQYFIENSKQTPTYGAKV
                     EDRKKMLSVAFQVGVNWKDQIFLDVTGRNDWSSTLVYADGHGSYSYFYPSVNGSWLIS
                     STYRDQLPEWISFAKIRGSWAQVGNDTSPYIINTAYQINTSTLNGTNYYGMSLQGTMY
                     DQDLKPERKNAWEIGLDWRFLNNRIGLDATYYKENTKDQIMEISVPAVSGITKQLINA
                     GNIQNKGVELALNTIPFQNQDWEWTLDFTWTKNMNKIVELHENVADYITLAGDVAYGN
                     YRIGSVAKVGASYGTLMTDSYYKFDKSSGLPMLVWTDGTRRSHYLRNEAKIVEIGSMI
                     PDFLGSISTGLKYKNWSLNISLDMRFGGKVASYNSRYGTAYGFMEESLKGTPGHGGVT
                     WTSKFDGKTYNDGIIPQGIIPQGTQITQPDGSIYTVGAGGVSSAGQSYQELFDKGVIE
                     PTHASAWTYRNNAWTMAGRDYGVVNNSWVEDLNYIALCDISLSYRLPSTACEKIKAKH
                     CVLTLNGHNLGYLLNSLPNNINPESVSGTAAAEFRIRSLTGVTSSFTFTVNVGF"
     gene            18920..20797
                     /locus_tag="ACZPB4_10700"
     CDS             18920..20797
                     /locus_tag="ACZPB4_10700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SusD/RagB family nutrient-binding outer membrane
                     lipoprotein"
                     /protein_id="HIR1098714.1"
                     /translation="MKKYHYITSLLLAGSSLLMSGCQDDFSELKQDPSTVTKGDIGYL
                     FAQGVLDFEPSDYTYWFYNADQMYQWTQLLVSTGGVTSTVFDGGMNSGFKSIDVLKYA
                     NEIKYVRSQMSEEESAQYEAYEAAINVLCAYMGIFDSDFIGNISHTEAAQALHGGTLT
                     PKYDSVERLYELWLNNMDEAITTFTTAQNQVFEGAQDAIYNGQKEKWAKLANSLKLKI
                     AARLISQNRQKAIQIAEQVANASCGVLNGTDDDFLFNKATYNSSNQDKTYHWNNGILQ
                     SVGGSKTLIDFMVNNRDLRVRFVFQKNEWNSNVVQLFFDAGKQAQIPHYIMESIDYSV
                     RADGKYKFNAWKGAGEPWVRYQGFPLDYNAGQQAGKFGDWFNYNINCKYNDDYIYEPF
                     SRFQQEQVYGRIDFTYPVAAGDPVIQDIEDNPWYGMYMTTAEVNLYLAEFKLLGANLP
                     GSAQDYFNKALRASVEEYDRLARSNKIPYYGTTYNYDPNEKPIDLVAGEIDEMMSYKD
                     YQLTGNKASDLEKVYIQQILHFLMSPIDAYSTARRSGVPKIGSSIFPRMDYSANGYPV
                     TNIPRRVALNAPNPTDLMYDNLIEAYKEQGLSVGSGDILNSERIWQDTNAPQWGAGPI
                     L"
     gene            complement(21046..21180)
                     /locus_tag="ACZPB4_10705"
     CDS             complement(21046..21180)
                     /locus_tag="ACZPB4_10705"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098715.1"
                     /translation="MRKPTHMVYLFMKVYPAFGGWQKNDIKRYDLNLTMDYRPWDNSA
                     "
     gene            complement(21540..21950)
                     /locus_tag="ACZPB4_10710"
     CDS             complement(21540..21950)
                     /locus_tag="ACZPB4_10710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007844659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098716.1"
                     /translation="MNIFSAFDTSVMVALLLGIEFLRSDIRTILYCKRNDPRILKSCL
                     YTLLILLTSLYSIVVGAMLHPEPVPVYELMPGFQIGVYGFSFSFILLAIACLYRKILP
                     FVLGGYAIIYVIGVLVPLLRFVVAMMDYFARARV"
     gene            complement(22128..22754)
                     /locus_tag="ACZPB4_10715"
     CDS             complement(22128..22754)
                     /locus_tag="ACZPB4_10715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
                     /protein_id="HIR1098717.1"
                     /translation="MKTKRTVFEVNDVYRVMENSELIYVLTNSEKLKHEEYKYEQMEM
                     DGLFLSDVLETLTPSRKKVAYAAIELYKRLKEGQVENPAVLSSGNVCKMMHPVLCDIT
                     TEEMWVLLLNSSSKLIRKVRISCGGINTAPVDIRVIMKQALYYNAVSFIMVHNHPSGA
                     RKPSSADDRLTEAVKKAAETLDIRLLDHVIVAGNIYYSYADEGRLQKR"
     gene            complement(23570..24790)
                     /locus_tag="ACZPB4_10720"
     CDS             complement(23570..24790)
                     /locus_tag="ACZPB4_10720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010185044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098718.1"
                     /translation="MKAERGLIFKYCHGKRTDRVPRILGENYNSDLIERLYEAGGNVM
                     LDLIIYLSSHHLKDLFGTSWFSVEDFCHKMGYNRTNLQRKLTEEQLTAMFGSRTPPKY
                     VVAGTAGKSVTHPIETVFEAAIYKLGLENLYYPVAGEDGRTSYNFVQILKRFDIVSDF
                     ETKKSTKRLYSAVISPEIKDFMFSLYNLLELQDYRNLPSRYRYFYLELSKMIYLIKYK
                     VKNNETPFYVLTVDQLAKRLGIEIAEPKYRKKKIASILTKMNGYLKYTNFNFSFIKGE
                     HDRWAYTVLFSFPQDTLRYFDEGQYAVVTKRFYKSLLKLYVELVYPEIELESRGKEVK
                     EQENDKELYGEFLQWANFSENIEKKKQLYINDFVAVFGRFPEGWTPERQQEVPDPEKF
                     ISSKSGADRKSPTV"
BASE COUNT         6353 a         5765 c         6041 g         6726 t
ORIGIN      
        1 gttttttgcg gattggtatc cctttatttt acccgtgtga tgaacaaggt ggaagggatg
       61 taccggaagt tgggtacgta ttggaagaag ttcatgttgg ggggggtgat gctgagtatt
      121 ttgatattcc tgttcccgcc gctatatggt gagggctatg atacgatcgg ctcgttgctg
      181 aacgggcagt tctcgcatat catggacaag agtttgtttt acgatctgaa cgatacctat
      241 ttcggggtct tgatcttctt gaccttgatc ttgcttacga aggtattcgc ttccagcgcc
      301 acgaatgccg gaggggggtg cggtggtatt ttcgctccta gtttgtatct gggctgtatc
      361 gccggtttta tctttgcgca tacgtctaat tatttcccgt tcacgatgta tatctcggag
      421 aagaatttcg ctttgctggg tatggcgggt atcatgtctg gggtgatgca cgctcctttg
      481 accggggttt tcttgatcgc cgagctgacg ggtgggtatg atttgttcct ccccttgatg
      541 atcgtctcga tcagttccta tatcacgatc cttatgtttg agcctcatag tatctactcc
      601 atgcgtttgg cgcagaaagg cgagttgctg acgcaccata aggatcgggc ggtgcttacc
      661 ttgctacggg cggatagcgt gatcgagaaa gatttccaga tggtgtctcc ggagatgacg
      721 ttgggcgata tggtaaaggt tatttcccga agcgggcgta acaccttccc tgttgtggac
      781 gagcggggcg tgttgctggg tatcgtcttg ctggataata tccggaatat catgttccgt
      841 ccggagttgt ataatcgttt ccatgtatcg aagttcatgg tttccgcccc ggccaagatc
      901 gtaatcaaca cgccgatgga tcagatcatg cagacgtttg atgatacgaa agcgtggaat
      961 cttccggtgg tcgatgagaa tggccattat atcggcttta tgtcgaaatc gaagatattt
     1021 aattcctatc gggaggtatt ggtcgataac ttttccgggg actaacttgt tacaaacaga
     1081 tccaatttat tatatatgaa gaaagaggat ttacgaatcg tatatatggg cactcccgat
     1141 ttcgccgtgg agagcctgcg tgccttggta gaaggtggat ataatgtggt aggtgtcatt
     1201 acgatgccgg ataagccgat gggccgtcat ggtagcgtgc ttcagccgag cgctgtgaag
     1261 caatatgccg tatcggtggg tcttccggtc ttgcagccag agaaattgaa ggacgaggca
     1321 tttttagagg aactgcgtgc cttgcgggcg gatttgcaga tcgtggtggc gtttcgtatg
     1381 ctgccggagg tggtctggaa tatgccccgt ctgggaactt ttaatctgca tgcctccttg
     1441 cttccgcaat accggggcgc cgctccgatc aactgggcgg ttatcaatgg tgatacggag
     1501 accggcgtga ctactttctt tcttacgcat gagattgata cgggtaagat catccgtcag
     1561 aaacatctgc cgatcgctga taccgacgat gtagaaaccg ttcacgatgc cttgatggcg
     1621 atgggggcgg ggttggttac cgagaccgtg gacttactgt tggatggaaa aacagacgct
     1681 atccctcaag aggagttcta taaggatgcc gccgagttgc gtccggcccc gaagatattc
     1741 aaggatacct gtcatatcga ctggaaccaa ccggtgaaga agatctatga tttcgttcgt
     1801 gggctttctc cttatcctgc cgcttggacg gaattgatct cagcggatgg caaacgtatg
     1861 gtcttgaagg tttaccagac ggagaagcgt ccggcaacgc ataacttccc ggtaggttct
     1921 atccatacag atcataaatc gtatatcgat gtggccgtga aggatggttt ccttcgattg
     1981 cattccttgc aacttgccgg aaagaaacgg atgaatataa cggacttctt gaacggtttc
     2041 aagcaaatcg cagaatatac ggttggctga tgaacgggac gagacgtatc atatacatta
     2101 cgttaggaac attttttctc atattgggag cgatcggcat ctttgtccct ttgctcccga
     2161 ccactccttt ttggttactg acttgttggt tttatgtccg tagctcggag agactttata
     2221 accgggtgat gagcaatcgt tatttcgggc cgcatattaa gggctttgtg gaagataagg
     2281 ctattccttt gcgttccaag attatcacga tcgctatcat gtggctatct acgatcatta
     2341 cttccctttt gctagtcggc tattggtggg tgaaagcttt gttagggctt atcagtatcg
     2401 gggtctcatg gcatatcctc tcttatccta ctaaaaaaga atgagataac ccgttcatcc
     2461 ataggattac tggggttatc cctcttttat cgctttctat cgtagcctta ctactttatc
     2521 ggtcttcttt caaggcctct tccaagctga ttcctagagc ttcagctact cccttaccgt
     2581 aagcggggtc tgccttgtag caattgcgta cgtggcgttg cttgatgaac agttgggcgt
     2641 tacccatcgc acgggcggta ttgccgaata acaactgttg ctcttccggc ggtatcaaac
     2701 ggaataaggc acccggttgg ctgtagtaat catcatcgta ctcacgctcg ttgtaattat
     2761 aaacatcccc gtgtactttc aaaggcggtt ccttcttctc gggagagtct ttccattcgc
     2821 cgaagctgtt aggttcgtaa ccctttgcgg ctccatagtt tccgtctaca cgcatcgttc
     2881 cgtcacggtg ataggcatgg aacggacaac ggggcttgtt caccgggatc tgctctaggt
     2941 tcacgccaag gcggtaacgc tgggcgtcgc cataagagaa tagacgacct tgtaacatct
     3001 tgtctgggga gaagccgata ccttcgacag tattcatcgg gttgaatgcg gcttgctcca
     3061 cgtcttggaa ataattttcc ggattacggt tcaactcgag gataccgaca tccattaacg
     3121 ggaagtcctt atgcggccat actttcgtga ggtcgaacgg gttgatcgga taggtctcgg
     3181 cctgctcctc agtcatcaat tggatctgga atttccattt cgggaagtcc ccacgctcga
     3241 tactctcgaa caaatcacgc tgatgggatt cacgatcctt ggcgatgatc gcagccgctt
     3301 cctcgtcact caagttcttg ataccttgca gggttctgag atggaacttc acccagatac
     3361 gttcgttctt attgttgata aaactgtacg tatggctacc gaaaccatgc atatgtcgat
     3421 aagagtaagg aatgccgcga gaactcatcg taatcgttac ttgatgcagg gcctcgggaa
     3481 gcaaagtcca gaaatcccag ttgttatcct cgcttcgtag attcgttttc gggtcacgtt
     3541 tgaccgcatg attcaagtcc gggaacttta ggggatcacg caagaagaat acgggggtgt
     3601 tgttgcctac caagtcccag ttaccctcct ctgtgtagaa tttcatggcg aatccacgga
     3661 tatcacgctc tgcgtcggct gctccgcgct ctccggctac ggtggagaaa cggacaaagc
     3721 agtcagtttt cttgcctacc tcgctgaaaa tagccgcttt cgtatacttt gtgatatcat
     3781 gtgtaacggt aaaggtaccg aatgcgccgg aacctttggc gtgcatgcgt ctttctggga
     3841 tcacttcacg gtcgaagtgc gctagcttct caatgaacca agggtcttgt aataccatcg
     3901 ggccacgtgg ccccactgtt tgtacgttct gattgtccgc aacagggcgc ccgttggcgg
     3961 cagttagttt tttgtcttcc ataactttag tttttatgtc gcaataaaga attttagata
     4021 aagtaatctt taaataaaac tgtttagaaa caacaattgt ttttaacttc ttgacaaaaa
     4081 taagatgttg ttagacagtt gtcaaatagt taatatctat aaatatatag acgggtagta
     4141 gaaactcagt ggggataggc gcatgagtta taaaagtatc ttagtttcat cgccccatac
     4201 acctaagata cttcgccaat gaacttagga tactttctct atgaaactaa gataccttgt
     4261 ttaaaaggta tggatacaaa aaagcggttg tctggcaaga tgccaagcaa ccgcggtatg
     4321 gtttgaaaaa atcaaatgtt caccttcccg gtaaaatggg gtgttactta tttattgtaa
     4381 ccccatttcg ttaactccga ctgaccgata gcagcgagtg atctcaagca gctatccaaa
     4441 aaatgtctaa taaaactttt catagctcat tttcttttta attaataaat ctgtgccttt
     4501 cgacacgttc taaatctcac ataacttttg aagtccgagt aacgaatgaa ttgaaaacct
     4561 aaacctttaa ccttttaacc tattactaac ctaatcccgg acttctgata accttaacct
     4621 aaaccttcct ctttttcatc gtgaggttta ccacatgcgg taaacccaaa ttgtccaagg
     4681 ttgaaaccct agcaaatcga tgtaacgttt aaacaatctc tttaccatat ttgctttaca
     4741 attatgtttt acgacacaaa tatacggcgt tattccatac gtggtatgtt ttatagcatg
     4801 ttttttgcgg attcctatgt tttcttgatc tatgataaaa aaagcgggaa tcagattcat
     4861 ataatgatag tatttgaacg tttggcatgt ctattgtgtt accatgccat tgagtttcta
     4921 tttctatttg ctacatttgc ggagctaaat gtaagataat gtaatatata tgagtagaaa
     4981 agaggagtac aaagagaaga atctattgta tttggacgag atcgcttcgg aagagggaac
     5041 ccagacatta ccgtgcggta tattatataa ggtaatacaa gcgggtacag gcaaggtatc
     5101 gcctaatagg gaaaacgtcg tttccgtaca ttataaggga acgttgatta acggaaggga
     5161 atttgataac tcatggaaac ggagttgccc ggaagccttt cgcttgaatc aagtgattga
     5221 aggctggcaa ttggctcttc aagaaatgcg ggtaggggat agatggataa tctatatccc
     5281 ttacagtttg ggttatggta atcgtgcctc gggtccaatc cctgctttct ccacattaat
     5341 atttgaggta gagttgttgg gaatcgccta attccaatca tagaatatat aataatgtat
     5401 ccgaagggag taaaaaagaa tagccatggc taaacccatg gctattctct ttttgcctca
     5461 ttagaggatt ggaaactttc tattgtttag gcgtatcatc cgtcttcttt cctttatcca
     5521 gccatttctc ttggatggtc tgcatcagtt catagaagtt agggatgaac atcgtggcga
     5581 atatcgtatt gatagccata ccgaatacta ccgccgcacc taaggatata cggctggccg
     5641 ctcccgctcc ggtagcgaaa agtaaaggca tgacacccaa tacaaaggcg aacgaggtca
     5701 tcaggatcgg acgtaaacga acgtgtccgg cttccaaggc ggaatcccgt atcggattac
     5761 cttccttccg gaaatcccgg gcgaactcta cgatcaagat accattcttg gcggacaagg
     5821 cgatcaataa gataataccg atctgggtat atacgcttac cggaaccccc atcacccagc
     5881 agccgataat agctcccaac aaggcgatcg gcaaacccat gatagccgcc aacggacttg
     5941 tccagctctc atattgagcc gagagaacca agaaagcgac tagcaacgcc atggcgaaaa
     6001 taatcaccgt cgtagatccc gctttcgtct cttgataagc gaccgaggtc cattcatatc
     6061 caaaattatc acctaattgc tcctgtatca gctcctccat cgctaggatc gcttctccgg
     6121 aactatattt cgggttggcg atacaagtaa tagccgctga tgaatacata ttatataggt
     6181 tgatctggtc taatcccaat tgttcgtcta attcgataaa agaggagaag ggtaccatct
     6241 cccccttact attcgccaga ctcaaacgga gtacatcatc gatcactttc tgcgcctctc
     6301 cgttcgcctc gatcttaact tggtaaatac gtccgaactc cacgaaatcg ttcacgtacg
     6361 ccgctcccat ataatagctg agcgtggaga atacttgatt caactgaaga ccgagcatct
     6421 gcaccttatc ccggtctatc ttcagtagat actgcggggt attggcctga tacatacaag
     6481 aaaggttcag caattgcggt ttcgagcggt agctggccag caatgtctcc acggcatgct
     6541 gcatctccgt cggacctagg ttcttacgat cctccaattg cagttgcaag ccgcccgaag
     6601 cgcccaaccc cgggatagcg ggcggtacca taccgaatac ctgcgcttct tggatagccg
     6661 atgcctcccg gttgaaacgg ttggtcacgg cctctgccgt atgctcctta cctttacgtt
     6721 cgttccagtt ctttaggatc acgaagaagg tggccgtatt ggattgctcc cctccaccca
     6781 tcacggagaa tccgctaacg ctgatgaatg atttcacctc ggggtatgtc tttaggatct
     6841 cgtcgatctg cttggtgacc gcctccgtcc ggttcaagct cgccgccggg ggtaattggg
     6901 atacgattag gaaatagccg tcatcctctt cgggtataaa ggttgtcggc caacgcataa
     6961 acaagataac cgctaccgcc gtgatgatac cgtaaacgat catcgccgct cccggtcgtt
     7021 tcagcatccg ctccacgatc gagtcgtaca tcttctgagt ctttccgtat accttattga
     7081 atcctttgaa gaggaagaat ttcggttctt ccgtattctt ctccaagaaa agggcgcaaa
     7141 gcgagggcgt aagcgtaagc gagttaaatc cgcttaatac ggtagcggcg gcgattgtca
     7201 aggcgaattg cttatagagc tgcccggaga taccgctgat aaacgttgtc gggataaata
     7261 ccgccaataa taccaatacc acgcccacga taggccctac gatctcatcc atggccttcg
     7321 ataccgcctc atgggccgta tatttcccgg tatcgaggag ccgggtggag ttctctacca
     7381 ccacgatggc gtcgtctacc accaccgcta tcgccagaat caagccgaat aaggtcaacg
     7441 tattaatgga gaagcctaaa gccgccatga ccgccagcgt accgatcaat gagaccggaa
     7501 tcgtaatgaa cgggatgact accgcccgga aattctgtaa gaataagaag atgaccaaga
     7561 ccaccagcaa ggttgtctcc aagaatgtga taagcacctc atggatggag gcgtcgatca
     7621 cctctgtcgt atccaaggtc actttgtatt ccacgccttc gggtaaggaa ctgcctaatt
     7681 ctttcatctt ggcctttacc accttcgata catccaagga gttggagccc ggcaactggt
     7741 agatcgctat cgcagcagtc ggctgtccgc ttaatttaga gaccacgttg taagaggagc
     7801 tgcccaactc tatgcgggcg atatccttca atcgcaggat cttgccacct tgcccggtct
     7861 taaggacaat attgccgaac tcatccggtg tcgtcaaccg tcctttcacg gtcaaggtat
     7921 attgataggg gttatccgcc cgtagaatcg gttggcctac gtaaccggcg gatacttggg
     7981 cgttttgcgt ggatatggct tgatagacca tgtccggcgt caagttacgg atacgcatcg
     8041 cctccgggtc tagccagata cgcatgctat agtttccggc tcccatcacc tgtaccgagc
     8101 ctacacccgg caggcgggtt agctggtcta tcatatttaa ggtggcgtaa ttacttaaat
     8161 acaacccgtc gtaaatggaa tccttggaac ttagggtaag catcatcacg atattggagg
     8221 attgcttgcg ggtggtgata ccttgtacga tcacgggttc cggcaagcta ctttgggcga
     8281 tactcacccg gttttgcacc atgacggtcg ccatgtcgat atccgttccc acggcgaagg
     8341 tgatcgtcag ggagtaagcc cccgaactgg aggagtttga actcatgtaa agcataccgt
     8401 ccacgccgtt tacctgttgc tcgatcggta aacctacggt ctgcgctacg gtctgtgcgt
     8461 ccgccccggg ataaacggcg gatacctgta cggtaggcgg cgtgatctcc ggatactggg
     8521 cgatcggtaa tatattgagg gtgaccaaac ccgctacgac gatgatcaga gcaagtaccg
     8581 tggcgaatat cggtctgtta ataaagaact ttaccatagc ttgcttattt tataggtttg
     8641 ataggcatgc catcccgtac cttaagcagg gcagaagtga catagggatc tttggggccg
     8701 ataccggcgg tcacttggcg aagcgtatcg tctaccagtt gccccacttc gataggacgg
     8761 tatcgtacga cattggagtc gttcacgata taaaggtact tccctaattg gtcggtaccg
     8821 atcgaggcgt cgcgaaccaa gaccgcatcc ggctgctcgg catacggcag ggtgatggtg
     8881 acgtataagc cactcttcaa tacatgcttc gggttatcca gattggcacg tacgttcagg
     8941 gtaccggtcg ataggtcgat atttggggat agataatcca gccggcccgt atacgcattg
     9001 ccgccatcct tgcctatgct gacgaggatc tcggtcggaa gtttcacggt gctatcgttg
     9061 cgggcggctt ccagcatcat cttcatgaac tggttatcct cgatattgaa attggcgaac
     9121 atcaagtcgt ccttgtataa ggtggccaag gtaaccggct ggacggctcc gttgatgtaa
     9181 ttacctatat cgtagctggc ccgggtaacc gcaccgtcga aaggcgcacg gatatagcaa
     9241 tagctcaagt tggtccgtgc ggtattcaac tccgcctcgg cattcttcac ggcagcctca
     9301 gactccgata cggtagcctc cgcttggatc acttgtatct ggcttacggc gccgctctta
     9361 gccgcctcct tcatacgctc gtagttactg cgtgcatatt ccagctgggc tttggaggtc
     9421 tttacggaag cctcggcttg ggtgacgtta tcttgatagg tgtccggttc gatcacgaag
     9481 ataagatcgc ccttcttcac ccggcttccg gccttgaggt aagaggtacg caagtatccg
     9541 ttgacacggg ctaccaagtc tactttcagt tgtgaactaa ggtatccggg gtattctttc
     9601 gtcaaggtaa tgtccctcac gatcggcgtg gatacgctta tggagggcac gggcgtttcc
     9661 atcggcttgc ttttcccctt gcaagacgcc agtaataagg cggaggctcc gataatccct
     9721 atgtaaacaa atgtcttcat atcttttgtc tttaatgatt atttatatta attgtttgag
     9781 tgggcttttg ttcgatcgga tcgaacggcc tacataggat tccatcctcc gcccaatgac
     9841 tgataaagct gtatcaagtt cagtagtgag ctaccttgag cctgtgtcaa ttggttctgg
     9901 taggtgagga gggagcgttg cgcgtccagt acgttttgga aaggcgtaag gccctgctta
     9961 tagaggtcaa gggaaagatc caaggtctgt tttccttggt ttaccacttc ccggagggct
    10021 acgatctgct tgatcgagtt cttgtacgag ctcatggcgt tatccacttc ctgtacggag
    10081 gtaagcacgg tctggttgaa ttgccggatc gactcgtcca actgggcttt cgccaaccgg
    10141 gtagcctgta tcttctgggt gccttggaag aagttccacg taagggtagg ggcgatctca
    10201 taggtcaggc tattgtgatt cgccagcttg tcgaagtcgt gggaggcgaa accgatcgag
    10261 cctttcacga atactttcgg ccaccaatcg gacttagagg ctccgagcga ggcggcaagc
    10321 gcattgacct gccgttctgc cgcacgtaca tccggacggc gtagcaacag gttggccggt
    10381 agccctacac cgaccggctc gatatattcc ggcaaggaag cgtctgtctc catgatcttt
    10441 tgtagatcgg aagggtacag gcctaacagg atcgccaagg agttcgcgta ttggatgata
    10501 ccggcctcca gcatcggtag ggaggctttc gtgctgtagt atacggattg cgcctgcgct
    10561 acgtccagtt tagagactag cccggtctca taccgtttct gggtgatctg tacgaccgtc
    10621 tgttgggagc ggcagttctg ttgcgctacc tttacctctt gttgcagttc cctcatattg
    10681 atataggagg aggctacttg agcgcaaagg gagaccatgg cggcgttgta ttcctctttc
    10741 gaggcggcga aattctcttt ctccgctttc acccggttcc ggatactccc gaatacgtcc
    10801 acctcccagt tcatatctac ggtagcactg gaatattggg tgatcgcctt gggtacctga
    10861 ttgatattgc cgctactttg ttgccgtgtc catccggcgg aaagccctag ggtgggcgag
    10921 tagcttcctt gtgccgaccg caggttggct ttcgccatgg cgatcctatc catcgccatt
    10981 tgcacggaat agttttgttt cacggctact tctatcagcg agtccagtaa cgggtcctta
    11041 aaatttctcc accaattatc ttctacggga agtgtctgct ggaaatcact cccttcctca
    11101 gaccatgacc cgggtagggc acggtctaaa tacgtatgct ctgtctgcgc cattaccccg
    11161 atcggtacca gcaagcacaa caaagcataa catgtcaggc gtaaatgttt gtgcataaat
    11221 atatatgttt agatttagct tttagcaaaa cagttaaggg tgggaaatgt ttgtatcttt
    11281 gtctatttat atatcctaaa aactgaaatg tatggatatc ttattggtta tactaggcgt
    11341 tatctgtttg ttggtgggat tggcggggtg ttttttgccg gtcttgccgg ggccgccggt
    11401 ggcgtattta gctttgtggc tgttgcattt tacgggctat gcggaattta cggttacgga
    11461 gttggtcgtg tggggattgc tggtcgtgtt ggcacaggcg atggactatg ttacgcccat
    11521 gctggggact aagtatagcg gagggtccaa gtggggaaat tggggatgtg ccgtgggaac
    11581 cgtggccggc atattcgtgt ttccgccttg gggaatcttg ctgggtcctt tcgtgggggc
    11641 tttcgtgggg gaacttttgg gaggcaaggc gtccggggat gcgttgaagg ctggttttgg
    11701 ggcgttcgct ggttttttat tgagtgtcgt gctgaaggtt accctttgcg gctattttat
    11761 ttatagcttt gtgagaggga taattaattg aagatggtaa ttaataatgt gagatatgtt
    11821 tgagaaaata gtagtggtag attctaccgg gttgaataca tggggagtgg agcgtttgaa
    11881 ggagcttgga aaagaggttg ttttttatac cggcattccg gaaacggatg aggagattgt
    11941 gaaccggatc ggggacgcag attgcgtact cgtctcttat aatacacaga tccggaggaa
    12001 cgtgatcgag gcttgcccga atatcaaata catcgggatg tgctgtaccc tctatagcga
    12061 gtctagcgcg aatgtggata tagccgccgc acgtgagcgg gggataacgg tcttgggtat
    12121 ccgcgactat ggcgatgagg gagtcgtgga gtatgtcatt agcgagctgg tccgtttgtt
    12181 gcatggtttt ggcgggaaac agtggaaaca taaggcgtat gagctgggcg ggcaaaaagt
    12241 aggcatcgtg ggattgggtc gcaccgggag aatgatcgct gacgctcttc gtttcttggg
    12301 ggctgaggtt tattatttca gccgtacccg taagccggat gccgaggccg ccggtatcgc
    12361 ttacctgcct ttgcgggagt tgctgccgga ggtggatatt ttatgtactt gcttgcctcg
    12421 taatacgatt cttctggggg cgggtgagtt tcgtttgttc ggtaatctga agatattgat
    12481 caatacgtcg gtagggccga ctttccgtgt cccggattta caacgttggc ttagcgccca
    12541 taaacggaat ttcttcttat gcgatgaggt gggtatcggg aattatgcgg ataccttgac
    12601 gcagttcgat aatgtcatat ataccccgaa agtctccggc cactcggagc aatgtatgga
    12661 gcgattgtcg caaaaggtaa tagcgaatat cgaaagctat cagaattgat atatccagtt
    12721 gtagagacgg ggcacgcccc gtctctacaa ctggggatag tattgatagg ggataagtcc
    12781 tatcaacctt ctttctcgat ctgttcctga acgatagcgt ctacgacagc tacggtagtc
    12841 aggttcacga tatcacgggt agagctttct acgtcggtga agtggatcgg tttgttcaat
    12901 cccatctgga tcgggccgat cgtctcggtg atacccagcg tatccaatag cttatatgcg
    12961 ctgttggcgg agcttaggtt cgggaagatc aaggtattca cgtcttgtcc tttcagcttg
    13021 ttgaacgggt acatatcgtc gcgcagcttc ttgtcgaggg cgaagtttac ttgcatctct
    13081 ccgtctacta ccatgtctgg gtatgtctta tgcaagaagt cgatcgcctc gtgcaccttc
    13141 agcgggctac cctgcttgtc ggccccgaag ttcgagtaag ataacatcgc catcaccggc
    13201 tcgtgagcga agaacttcac ggcgtcgtgc gtcaggcggg cgatatcgat caatacctcg
    13261 gccgacgggt gacggttgat cagcgtatcg gccatgaaga aggtaccctt cttacaagtc
    13321 aggatgttca aggcaccgaa atgcttgtaa ctcgggcgga tgccgatgat ctgctccgcc
    13381 atcttggtaa cctccgagta gcggctgtat acacccgtca cgaaagcgtc ggcgtcgccg
    13441 gtagccacca tcatcatacc aaaggcgtta cggtctacca ttttctcgca agcctctgag
    13501 taagtcacgc cctcgcgcgc cttcttgtcg gtaaggatac gggcgtagcg gtggcggcgt
    13561 tccgtctcac ggtcgtggcg gaggttgacg atctcgatac cgtccagact gatattctcc
    13621 tcggcggcga tcttggccag acgctcctcg ttacccagca agatcgggaa acagatacct
    13681 tccgctttcg cctcggcggc ggctttcagc atattcacgt ggttcgcctc ggcgaatacc
    13741 acccgtttcg ggttcgcttt cgccatatcg gtgaacgagc gcaagagttt attatcgtac
    13801 cccatcatct cacgcaaatg gttggcgtag ccctcccagt cggtgatcgt cttgcgagac
    13861 acgcccgagt cgatagcggc tttcgccacg gcgcaagata cacgggtcag caagcgggga
    13921 tcgagcgctt tcggaaggat atagtcgcgt ccgaaagtgg ttcgtttcag cttataggcg
    13981 gcgttcacca cgtcgggaac cggctccttg gcaaggtcgg cgatggcgta gacggcggcc
    14041 cgcttcatct cctcgttgat cgccttggcg tgcgtatcca aggcgccgcg gaagatataa
    14101 gggaatccca gcacgttgtt gatctggttc ggatagtcgg aacgtccggt agcgaagatg
    14161 atatcgtccc gcgaggccat cgcatcggcg taggagatct ccgggttcgg gttcgccaag
    14221 gcgaatacga tcgggtcggc gttcatgcta cgtaccatct ccttggtcaa tacgttcgcc
    14281 acggagaggc ccaagaatac gtcggctccc accacggcct cttgcaaggt cttgatcgga
    14341 cggtcggtag cgaactcccg cttggcggcg ttcaagtccg ggcggctggt agagatgacg
    14401 cccttgctgt cgcacatgac gatattctcc ttgcgcgctc ccagcatcac gtacagtttc
    14461 gtacatgaga tagaggcggc tccggcgccg ttcaccacga tcttcacgtc ctcgatcttc
    14521 ttgccggcga tctccaaggc gttgatcagc ccggcgccgg agatgattgc cgtaccatgc
    14581 tggtcgtcgt gcatgacggg gatatccagc tcgttcttca agcgagtctc gatctcgaaa
    14641 cactccggtg ccttgatatc ctccaagttg attcctccga acgtgggcga gatcgccttc
    14701 acggtctgga taaacttctc cggatctttc tcgttcactt cgatatcgaa tacgtcgatg
    14761 cccgcaaata tcttgaatag caatcccttg ccttccatca ccggcttacc ggccaagggg
    14821 ccgatatcgc ccagcccgag tacggcggta ccgttggaga ttacggctac caaattacct
    14881 ttcgccgtat attcgtacgc gtccagcgga ttcttctcga tttccagaca cggctcggct
    14941 acgcccggcg aataagccag ggataaatcc gtttgcgtgc tatgaggctt tgtcgggata
    15001 acctcgatct tacccggttt accctcggca tggtaccgaa gggcctcctc ttttgtaatc
    15061 tttgccatag atgtttttat tagttgtttt ttgactgtcc tatttgaaac caccgcgaaa
    15121 gtaacaaatt attatgagtt cgcttggttt tgcttacaaa tagttgctta tgttttcctt
    15181 aataagtgaa aaagaataag caaaaaaagg cttgggtgca taccggaggt ttgcgtacaa
    15241 cttagttcca ccatattcaa atagtatact cgaaacttat agggtgaagg tatcaggtat
    15301 tttcaattta gaacagagta gtcatggtac ttaagtgaaa aatcaataaa acacgaaata
    15361 caccaaccac agaactttag atttcaacgc caaacaatag acgctgtttc gccaagagat
    15421 agttaatttt attaccataa aaaatcatta gttatgttga aaaactttaa gccggtcaat
    15481 ctaatcctcg tagtgggagc tatggcgttg cctgtaagcg catatgccga cttggtaccg
    15541 gagaaactag acgtaagtat ttccttgcag agcggaaaag taacgggagt tgtagaggat
    15601 aatttcgggc ctgtagccgg agcgtctgta gtagtaaaag gcacaaccaa tggaacgatt
    15661 accgacatga acggtaactt ctcgttggaa ggagtaaata acggagactt gatccagatc
    15721 tcctttatcg gatacatgac ccaagagctt atctacaagg ggcaggccat cagcgtaaag
    15781 cttgccgagg atacgcaaaa actggacgag gtagttgtta ccgccttggg tatgaaacgc
    15841 tcggaaaaat ccctaggcta cgccatgaaa gagataaaag gcgacgaatt gaacgctaac
    15901 ttgattaacc cggtagccgc cttgcaaggt aaagtggccg gtttggaaat ctcaggttcg
    15961 gatggtggta tgttcggttc ctctaaagtt cagatccgca gtgcttccac attaggaaag
    16021 aacaaccagc cgatctatgt gatcgatggc gtgatcttgg acaactccat caaggaaggt
    16081 aatccggact gggactccaa ccccaatgac tacggtaacg agttgaaaaa cttgaacccg
    16141 gatgacttcg agtctgtatc cgtattgaag ggagcggcgg ccacagccct ctatggttcc
    16201 cgcggtttga acggcgcgat cgtgatcacg accaaaagcg gcaagagcgg acaaggactg
    16261 ggtatcaata tctcacaatc attcggtatg gatgtgataa cccaaacacc tagtttccaa
    16321 aacgaattcg gtaacggtat cattgcaggt aacgtagatt acggcgataa aaacgctaat
    16381 ggagactatt acatctatga caacttcgga caatatccta ccaacgcaaa tggtcaattc
    16441 tcattgatga acgatcaagg tatgtcgtgg ggacccgcat tcgatggacg tgagatacaa
    16501 tactatgacg gttccacaag agcctactct cccgtaaaga ataacttcca caaggcatat
    16561 caaaaaggat tcagttcgaa tacaaacgtg gcgatcagcg gaggcaatga gaaaacgaca
    16621 ttttatacct cattgtctta caagcatgta gatggtacga ctccgaataa tagcttcgac
    16681 cgtatctcct tcctaggcaa ggcctcgcac atgttccacc ccaaaatcaa actggaagcc
    16741 agtatgtcgt tcgccaactc tatgccaaag aactctccga tcaacattgg agagaacttc
    16801 gcaagcggcg tgtggggacg ttcatatgat ccatcaactg caaaggacaa atataaaggc
    16861 gtacacggag gtttggccag ctcaagctat ggcgatgagt atggtaatat gccgggaatc
    16921 ggtacttggt ggagcgtcta tgagaacgat taccgacaaa aagagatctc agtccgtcct
    16981 gtcgtgaaat taaatatcga cctattggat tggttgaagt ttaacgtgaa aggtagctac
    17041 aactactact atacccgctt tgagaacaag caacccggct ccggttacgc caatgaagga
    17101 ggttactatg gtatcggaca gaccactaag gaacaaacta acttgaatgc caactttatg
    17161 tttaacaaga cttttggcga ctttacggtg aatggtttct tacatggtga attctacgag
    17221 aacttccagc aggcacagtc gatgaacacg aatggtggcc tgatcgctcc caaccaatat
    17281 tttatcgaaa actcaaagca aacacccact tatggcgcaa aggtagaaga ccgcaagaag
    17341 atgttgtccg tagctttcca agtcggcgtt aactggaaag accaaatctt cttggacgta
    17401 accggacgta acgactggtc ttctaccttg gtttacgccg atggacacgg atcatattcc
    17461 tatttctacc catccgtaaa cggatcgtgg ttgatctcaa gcacgtatcg cgatcagtta
    17521 ccggaatgga tttctttcgc taagattcgc ggttcatggg cgcaagttgg taacgataca
    17581 agtccttaca tcatcaacac ggcataccaa atcaacacat ccacgttaaa cgggacaaac
    17641 tattatggca tgtcattgca gggaaccatg tacgaccaag atttgaagcc agagcgtaag
    17701 aacgcttggg aaattggctt ggattggcgc ttcctaaaca accggatcgg tttggacgct
    17761 acctattata aagagaacac gaaagaccag atcatggaaa tctcggttcc ggccgtatct
    17821 ggtatcacca agcaattgat caacgccggt aacatccaaa ataaaggcgt ggagttggcc
    17881 ttgaacacga tcccgttcca gaatcaagac tgggagtgga cattggactt tacttggaca
    17941 aagaacatga acaaaatcgt ggaattgcac gagaatgtgg cggattatat tacactggcc
    18001 ggtgatgtcg cctatgggaa ctaccgtatc ggttccgtgg ctaaggtagg ggcctcatat
    18061 ggaaccctga tgacagatag ctattataaa ttcgataagt catccggttt gcccatgttg
    18121 gtttggacag acgggacacg ccgttctcat tacctgcgaa acgaagcgaa gatcgttgag
    18181 atcggttcca tgattcctga tttccttgga tcaatatcta ccggattgaa atataagaac
    18241 tggagtttga atatctcatt ggatatgcgt tttggaggaa aagtagcttc ctataactcc
    18301 cgctacggta cggcctatgg cttcatggaa gaatccttga aagggacacc gggacatggc
    18361 ggtgtcactt ggacatccaa attcgatgga aagacttata acgacggtat catcccacaa
    18421 ggtatcatcc cgcaaggcac gcaaatcacg caacccgatg gttcgatcta tactgttgga
    18481 gcgggtggag tgtcttctgc cggacagtct tatcaagaat tgttcgataa gggcgtgatc
    18541 gaaccgacac acgcttcggc atggacatat cgcaacaacg cttggactat ggccggtcgc
    18601 gattatggtg tggtaaataa ctcatgggtg gaagacttga actatatcgc attgtgcgac
    18661 atttctttaa gttaccgcct gcctagtacc gcttgcgaga aaatcaaggc taaacattgc
    18721 gtattgacgt tgaatgggca caacttgggt tacttattga actcattgcc aaacaacatc
    18781 aatccggagt ccgtttccgg tacagctgcc gccgagttcc gtatccgttc tctgacgggt
    18841 gttacctcca gtttcacgtt cacggtaaat gtaggtttct aaattcattg attaacgcat
    18901 aaaattaaag aataagaata tgaaaaaata tcactatata acatctttgt tattagctgg
    18961 atcatctttg ttgatgagtg gttgtcaaga tgatttctcc gaattgaaac aagatccctc
    19021 gacggtgaca aaaggcgata tcggctattt gtttgcccaa ggggttttgg attttgaacc
    19081 atccgattat acctattggt tttataatgc agaccagatg tatcaatgga cacagttgtt
    19141 ggtcagcaca gggggcgtga cctctaccgt atttgacggt ggtatgaatt ccggattcaa
    19201 atcaatcgat gtattgaaat atgccaatga gatcaagtac gttcgctctc aaatgtcgga
    19261 agaggaaagc gcccaatatg aagcctacga agctgccatt aatgtcttgt gcgcttatat
    19321 gggaatcttc gactccgatt tcatcggaaa tatttctcac acggaggctg cacaagcgtt
    19381 gcatggtgga actttgacac cgaaatatga cagcgtggaa cgcttgtatg agctgtggct
    19441 gaacaatatg gacgaagcga tcacgacttt cacgacagcc caaaatcaag tgttcgaggg
    19501 agcgcaagac gctatttaca acggtcagaa agagaaatgg gcgaaactgg cgaattcctt
    19561 gaaattgaag attgcggctc gtttgatctc tcaaaaccgt cagaaagcga tccaaatcgc
    19621 cgaacaagta gctaatgcct cctgtggcgt gttgaatggc acggatgatg atttcttgtt
    19681 caacaaggct acttacaatt catccaacca agataagacc taccactgga acaatggcat
    19741 tttgcaaagt gtgggaggct cgaagacgct gatcgacttc atggttaaca accgtgacct
    19801 gcgtgtccgt ttcgtttttc aaaaaaatga atggaattcc aatgtcgtac agttattctt
    19861 cgatgctggc aagcaggcac aaattcctca ctatatcatg gagagcatcg attattcagt
    19921 aagagctgac ggtaaatata aattcaacgc ttggaaagga gccggagaac catgggtacg
    19981 ttaccaagga ttcccattgg attacaatgc cggacaacaa gctggtaaat ttggggattg
    20041 gttcaattat aatattaatt gtaaatacaa tgatgattat atctatgaac cattctctcg
    20101 cttccaacaa gagcaagttt acggtcgaat agactttact tatccggttg cggcaggaga
    20161 tcctgtgatc caagacatcg aagacaatcc ttggtatggt atgtatatga caacagccga
    20221 ggtgaacctg tatctggctg agttcaagtt attgggagcg aacctgcccg gatcggccca
    20281 agattatttc aataaagcgc ttcgcgcttc tgttgaggaa tacgaccgtt tggctcgctc
    20341 gaataagatc ccgtattacg gtacgactta caactatgat ccaaacgaga aacctattga
    20401 tttggtagca ggcgagatcg atgagatgat gtcttataaa gactatcagt tgacaggaaa
    20461 caaggcttct gatttggaaa aggtatatat ccaacaaatc ttacatttct tgatgtctcc
    20521 gatagacgct tactcgaccg cccgtcgttc cggcgtgcct aagataggat cttcaatttt
    20581 cccacgtatg gattatagcg ctaatggtta tcccgtgacc aatatcccgc gtcgtgtagc
    20641 attgaacgca ccgaatccaa cagacttgat gtatgataac ttgatcgagg cttataaaga
    20701 acagggctta agcgttggct ccggcgacat attgaatagc gagcgtattt ggcaggacac
    20761 caatgcgccg caatggggag ctggtccgat cctttaatgc actcaagaca atgttaaata
    20821 taaagagagg atagcggcat cctctcttta tatttaactg tctaaaactc cttatcgtta
    20881 gtcacaggcc cacatactcg agaaagaagc tttcgtgata atatcgactc ccttatccca
    20941 attgatccga tccgcatgat cgtccggtaa gttgtagtag ggacgaggat cggtatgatg
    21001 ccaggtgata ggaataccca ccttggcgaa cgattcgcta tcgtctcacg ctgaattatc
    21061 ccatggacga taatccattg tcagattcaa gtcgtatctc ttgatatcgt tcttctgcca
    21121 accaccgaaa gcagggtaca ctttcatgaa gagataaacc atatgggtag gcttcctcat
    21181 tattgttaca accgatcata tcgaaattca aatatccttt catattcctt atctccggta
    21241 acacgacttt atttaaactt tgattaatgt gtacaatact ttggtaattt ttcaccgaaa
    21301 tattaattaa gtcattcgct tacttttgcg ttttatgcgt taacaatcgg tgtagcctgt
    21361 atacggcgac acttcttcat cgttattttt catacagtaa agacacttgg ctgtaacttg
    21421 ccatttgcgg aatactggaa cctttgccgg gcaaaaagcc ggacctggat cggaggaaaa
    21481 gaataggggg gaggcaaccc acagaaaggg cgatccgata caatcaataa attaaccagc
    21541 tacacccttg ctcgagcgaa ataatccatc atagccacta caaatctaag taacggtacc
    21601 agtacaccta ttacatatat tatagcgtat cccccaagga caaaaggtaa tattttacga
    21661 taaagacatg ctatagcaag taatataaac gagaaggaaa agccataaac ccctatttga
    21721 aaaccgggca tcaattcata aacaggtacg ggttccggat gaagcatggc accgaccacg
    21781 atagaataaa ggcttgtcaa taatataagc agcgtatata agcaactctt aagaatcctg
    21841 ggatcattcc ttttacaata gagaatcgtt cggatatcac tcctaagaaa ctcaataccc
    21901 agtaagagag ccaccataac gcttgtatca aaagcagaaa atatattcat tccgattacc
    21961 tttaacgtga agatatgtat ttattctgaa aagctacgtc tttgcgtatt ttacgatatc
    22021 gtatccgata gtcagaaaag catttttggg gctctttttt ggggatgact gccaaaaaag
    22081 aaccccgaag ctgaaattca ggcagacggg attcctcccg tccatcttta ccttttttgc
    22141 aatcttccct cgtccgcata gctataatat atattaccgg caacaatcac atgatctaac
    22201 agacggatgt ctaatgtttc agcggctttt ttaaccgctt ccgtcaagcg gtcatccgca
    22261 ctgctaggct tgcgtgctcc tgacgggtgg ttatgcacca tgataaaaga tacggcgtta
    22321 taatacaatg cctgcttcat gataacccgt atatccacag gggcggtatt tatcccaccg
    22381 catgagatac ggactttacg gatgagtttg gacgagctgt tcaacaacag cacccacatc
    22441 tcttcagtag tgatatcgca caaaacggga tgcatcattt tacaaacatt accgctggac
    22501 aaaaccgcgg gattttcgac ttgtccttct ttcagccgtt tatacagctc aatcgccgca
    22561 taagcgactt ttttacggct gggtgtcaat gtttccagta catcagacaa aaacaacccg
    22621 tccatttcca tctgttcata cttatattcc tcatgtttca gtttctcact gttcgtcaag
    22681 acatagatca actcgctgtt ttccatcacc cgataaacgt cattcacctc aaatacggtt
    22741 ctcttcgttt tcatactgcc aaaaattaaa agattaatac tcgcaaacat cgcttgtcgc
    22801 cccaaccata aatttttcct caactgattg ggaacagtgc tttgaagaga aagcgggaaa
    22861 gacggatatt aggacgggat tgaactggta aatactacct tcccaaaggg aaggctggag
    22921 atttggcttt tcaatatcgg acgttccgcc cccgcctacc ttcgcaatgt tcctatcagt
    22981 tcaggaaaaa atcatcatac ctctcttccg gcatagccgg agcataaagc gttagggata
    23041 gcagggaaaa gcccggaggg taacgaggac ttgcaacgga tagcccgccc gaaagggaac
    23101 gccctagaaa taagtttagc gtaaaagagc aagacaccct ttcaggcata ttaaaaaccg
    23161 taaaattcaa catctacttc cggaaaatat ttttccgaaa gtaagtatgg agcgtgtgaa
    23221 gggaaaattc attttcccgg tcatttcttt gtatgtagtt tttcggggaa tataaagggt
    23281 tagggtttta ggtatactta tgtaatatgg tggatcattt tacacagcta tcaggctttt
    23341 ttagaagatt ccgtttcttt attcgactat ataacaatca tgtactgact taccccccta
    23401 tcactccttt cttgaaaaga gtggatactt tcacacagct atcactatat tacggacggt
    23461 tgtacacaat tggagcagga aagagggacg gtcgcataca gctggaagta aagaacggga
    23521 catctgtaca caactaaaac agcaaaaaaa acgtgaaaag tgaacgattt tacacagttg
    23581 gggactttct atcagcacca ctctttgaag aaatgaattt ttccggatca ggaacttcct
    23641 gctgcctctc tggtgtccac ccttcgggaa acctgccgaa aacagccaca aaatcattta
    23701 tatataattg ctttttcttc tcgatatttt cagagaaatt ggcccactga aggaactcgc
    23761 catacagttc cttatcattc tcctgttctt tcacttcctt tcctctggat tccaactcta
    23821 tctcaggata aaccagctcc acatataact taagcaggct cttataaaat cgcttcgtca
    23881 cgaccgcata ctgtccttca tcgaaataac gcaacgtatc ttggggaaac gagaacaaaa
    23941 cggtataagc ccatctatca tgctcacctt tgatgaagga aaagttgaaa ttggtatatt
    24001 tcaggtagcc gttcatcttc gtaagtatcg aggcgatttt ctttttccga tatttgggtt
    24061 cagctatttc tatccccaac ctcttagcca gctgatcgac tgtcagcaca tagaaaggag
    24121 tttcgttatt cttgacttta tacttgatca ggtaaatcat cttggatagc tccaagtaaa
    24181 aataacgata acggctgggt aagtttcgat aatcctgaag ttccaagagg ttatagagcg
    24241 aaaacatgaa gtctttaatc tccgggctta tcaccgccga atacagcctt ttcgtcgatt
    24301 tctttgtctc gaagtcggaa acaatatcaa atcgtttcaa gatctgcacg aagttataag
    24361 atgtacggcc atcttcaccg gctaccggat aatacaagtt ctccaatccc aatttataga
    24421 tcgccgcctc aaataccgtc tctatcgggt gagtgaccga tttccctgcc gtaccggcaa
    24481 ctacatattt cgggggtgtc ctgcttccga acatagctgt caactgctct tcggtcagtt
    24541 tccgctgtaa gttggtacgg ttataaccca tcttgtggca aaaatcctcc acagagaacc
    24601 aagaggtacc gaacaggtct ttcaggtgat ggctgctcag gtatatgata agatccagca
    24661 tgacattgcc acctgcctca tacaaccgtt ctatcaggtc ggaattataa ttttccccaa
    24721 gaatcctggg aacacgatca gttcttttgc catgacaata cttaaaaatc aatcctctct
    24781 ctgctttcat tgccacaatg atagacatac cggggcacat acacatcatc attatcactt
    24841 tactttaaag atacgaacaa tatgaaaaac aaagatataa tttac
//
LOCUS       DBMDTB010000061        24174 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_725_length_24174_cov_10.345075, whole genome shotgun sequence.
ACCESSION   DBMDTB010000061 DBMDTB010000000
VERSION     DBMDTB010000061.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 24174)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 24174)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24174
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_725_length_24174_cov_10.345075"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            36..728
                     /locus_tag="ACZPB4_10725"
     CDS             36..728
                     /locus_tag="ACZPB4_10725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster assembly scaffold protein"
                     /protein_id="HIR1098719.1"
                     /translation="MIYSHEVQHMCVVKKGANHQCAPIPEEGKWVRATQITDISGLTH
                     GIGWCAPKQGGCKLTLNVKEGIIQEALVETIGCSGMTHSAAMASEILPGKTLLEALNT
                     DLVCDAINTAMRELFLQIVYGRTQSAFSEGGLPVGAGLEDLGKGLRSQVGTMFGTLAK
                     GPRYLEMAEGYCTRMALDADDEVIGYEFIHLGKFMDMVKKGMDANEALEKAKGSYGRF
                     KEAVKYIDPRNE"
     gene            721..912
                     /locus_tag="ACZPB4_10730"
     CDS             721..912
                     /locus_tag="ACZPB4_10730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098720.1"
                     /translation="MNKKTFTRVLIGLSVITAVATLITYFVMKPEKPWLAFYVACCGG
                     VLVFNFLISLFLVNKNFKK"
     gene            922..1923
                     /locus_tag="ACZPB4_10735"
     CDS             922..1923
                     /locus_tag="ACZPB4_10735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007658687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGGtGRT protein"
                     /protein_id="HIR1098721.1"
                     /translation="MALFESYDRRIDHINAVLNEYGINGIEDAKAICDAKGIDPYTMC
                     KETQPICFENACWAYVVGAAIAIKKGCTNAAEAAEAIGIGLQAFCIAGSVADDRKVGI
                     GHGNLAARLLREETKCFAFLAGHESFAAAEGAIKIAEMANKVRKEPLRVILNGLGKDA
                     AKIISRINGFTYVQTQFDYMTGEVNVIEEKAYSNGLRAKVKCYGADDVREGVAIMRKE
                     GVDVSITGNSTNPTRFQHPVAGTYKKECMENGHPYFSVASGGGTGRTLHPDNMAAGPA
                     SYGMTDTMGRMHGDAQFAGSSSVPAHVEMMGFLGMGNNPMVGATVAVAVAIEEAMKK"
     gene            2018..2878
                     /locus_tag="ACZPB4_10740"
     CDS             2018..2878
                     /locus_tag="ACZPB4_10740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HIR1098722.1"
                     /translation="MTLNIDQESCIKCGKCVRVCPSDIFTQERAGETIGLVRVESCIV
                     CGHCVDVCPTGSVLHSEFPPEKTHTIDYSQMPTPEQVMLLIKSRRSNRTLTSRPVPKE
                     MLDKIVEAAHSAPTATNSQSLSFTVVTDPRKLRQVSDYTIGVFDSLAKLLLNPVVKCV
                     VKPFMKDVYKYVPVFNRLKEEHKAGKDPILRKATALLLIHTPKSNRFGSEDANLAYQN
                     ASLMAQSLGVSQIYMGFVLTAIRQEGKDTLAETLGIDGKIQAIMALGIPAFKYPKYTD
                     RKEIVKNYIE"
     gene            complement(3016..3192)
                     /locus_tag="ACZPB4_10745"
     CDS             complement(3016..3192)
                     /locus_tag="ACZPB4_10745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005677594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4250 domain-containing protein"
                     /protein_id="HIR1098723.1"
                     /translation="MSLPNDPMMLFSFINMKLRDNYSSLDDLCEDLQVNKKSLLTKLK
                     DAGFEYSPEHNKFW"
     gene            3356..3808
                     /locus_tag="ACZPB4_10750"
     CDS             3356..3808
                     /locus_tag="ACZPB4_10750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper resistance protein NlpE"
                     /protein_id="HIR1098724.1"
                     /translation="MKKYVLVVAVAAALFSCSGNPKADATQTDKNKQETAQVPDMHNA
                     ETSLDYWGVYEGTLPAASSPGIKTTLTLNKDKTFTLRSEYIDEKDGIFNDKGTYTLDG
                     NILTAKQEGGDITYYKVEEGQLKMLDQQKQPVTGDLAKFYILKQTKKF"
     gene            4109..5728
                     /gene="abc-f"
                     /locus_tag="ACZPB4_10755"
     CDS             4109..5728
                     /gene="abc-f"
                     /locus_tag="ACZPB4_10755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protection-like ABC-F family protein"
                     /protein_id="HIR1098725.1"
                     /translation="MSIVAQKITYIHPDNQVLFKGIDLTINKGQKVALVGNNGSGKST
                     FLRILAGTLQAQEGEIIYPTPPYYVPQHFGQYDNQTVAQALRIDGKLEALRAITEGDA
                     SLSNFNTLADDWTIEERSLAALHAWGLEHILLSQPMRTLSGGEKTKVFLSGIEIHQPS
                     ILLLDEPTNHLDRRSREKLYDFITSCRITLLVVSHDRTLLNLLASIAELSVGGITLYG
                     GNYDFYKEQKEQEQASMQEKLEAKEKELRRVRKTAREVAERKQKHESRGEKQSVRKGI
                     PRIMMGGLKENAEKSASKLKEVHEDKMENLANELKRMRSSLPDLQGMKLDFSASGLHE
                     GKILVTAKEINFGYAEAGDLWPSPMSFQIKSGERWLIQGDNGSGKTTLLKLITGQLPP
                     RSGSLIRADFSSIYIDQEYSIVRNDRTVYEQAQAFNERHFQEHEIKTLLNRFLFPHDT
                     WEKSCGKLSGGEKMRLAFCCLMISNQTPDLFILDEPTNNLDIQSIEIITSMVRAYRGT
                     ILLISHDAYFIRELGIHQIITTFAGRLKTNL"
     gene            5725..>6410
                     /locus_tag="ACZPB4_10760"
     CDS             5725..>6410
                     /locus_tag="ACZPB4_10760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HIR1098726.1"
                     /translation="MKTLLDVHTHTVASGHAFSTLQEMAVAASEKGLKLLGITEHAPG
                     IPGTCSPIYFRNLHVVPRRIYGVELLLGAELNIIDYKGTIDMGEEYFPMLDIRIAGIH
                     SLCYKPGTVEQNTEAMIGAIRNPHVHIISHPGDGTAEVDFEPIVLASKEHHTLLEINN
                     SSLNPVRKKLTARDNNLTILRLCKKYEVPVILGSDAHISFDIARYDHIYELLQETRFP
                     EELILNDKVEA"
     assembly_gap    6411..6510
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<6511..8236)
                     /locus_tag="ACZPB4_10765"
     CDS             complement(<6511..8236)
                     /locus_tag="ACZPB4_10765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HIR1098727.1"
                     /translation="MRRIVLLITICCQVFWVAAQKKAPKWMDKQRKAVVTVTTYGKDN
                     QKKASGTGFFITETGEALSGYSLFKDAARATVTDADGKEYPVSRILGADELYDVIKFK
                     VEVPKKAVFLPIAREPISQGVIAYLMPYSTGKITKFGEGPVSEVSKLKEPFSYYKLSM
                     ALESGQVNAPVLTADGEVFGLAQEDASGKKEDSYAVSAGYANSLTIQSADAFNSTYSR
                     IGIRKAWPSDVSQAQVSLYLMASSQDPKTYLATLNDFIATFPDSPDGYLNRANHYAYH
                     RADLAPTEAEQGACLDKALEDINTASRFSERKGDVWFNRAKLIYGVAVADTTLNKEQW
                     TVDAATEAIQKAIGEEDLPVYRQLEGDIHFYKGDFEQAFDDYMKVNDSDMASSTSWYW
                     AAKAKANIRGANFGDIIALLDSAIAKCGNPPTNEAAPYILERVDLRLKLMQYKEAVDD
                     YDLYYDLLKGQVGDRFFYYREQAKFRMNDFPGALADIQSAIRLNPGDPTYPAEEASVY
                     IRMENYDQALRSLENALRIAPDFASCYRLRGICYVRQGKKAEACEAFNKAKELGDPVV
                     DKLIKEHCK"
     gene            8362..9087
                     /locus_tag="ACZPB4_10770"
     CDS             8362..9087
                     /locus_tag="ACZPB4_10770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HIR1098728.1"
                     /translation="MRLKSCMLMCSLFMASLASASNFASDSFKTKSGKELIITFIKHG
                     SLMLTYDNHSIQVDPVSEYADYTTFPKADIILITHEHGDHLDPKAIQAVEKSGTEIIA
                     NENSQKKLGKGKVLKNGDTDTSISYMKIEAVPAYNTTPGRDKYHPRHRDNGYILTFDG
                     LRVYIAGDTEDIPEMKDLKDIDIAFLPVNQPYTMTVPQAAKAARMFSPKILYPYHYGN
                     TKIGELKDALKGSGIDVRIRELQ"
     gene            complement(9079..10287)
                     /locus_tag="ACZPB4_10775"
     CDS             complement(9079..10287)
                     /locus_tag="ACZPB4_10775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1098729.1"
                     /translation="MRTSDNMKGTLADIASLVKDEFKTISTSYAILLVLVGGIFLYGL
                     LYNYMYAPDLVRNAPVVVVDDSKTDLSREYIRLLNATPQVSVIADGLDYAEAQEWMKE
                     GDAVGILYLPSDFETRVARGNESLFIMYQTTSAFLYYMAMQEASSGAMLALNDRYRPE
                     MLVFLPQQDASKIVSAQPISVVGTALYNFTEGYGTYLIPAVLIVIMFQTLLMVIGMIS
                     GEERDSGTIVRFASEGLSFGRIARVIISKTFVYCVLYMIFALFLLGLIPLLFGLPDIG
                     NYLNTLILLIPFLLATSFFGLAASYFFTDSEAPLLMIAFFSVGLIFLSGVSYPLELMP
                     WYWQMAHYIIPAAPATLAYVQLNSMGASIEQVGVEYVTLWVQSVVYFLLACWVYRRNI
                     LKASRALSSL"
     gene            complement(10271..11446)
                     /locus_tag="ACZPB4_10780"
     CDS             complement(10271..11446)
                     /locus_tag="ACZPB4_10780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1098730.1"
                     /translation="MLKKSPFYMVLRRELDRMVSRRLYFGVCIVLPLFCIFFMSTIFG
                     SGQMENIPIAVVDQDNTSMSREIIRQVEAVPTFRVTRHYTDQETARRATQAKEIYGYL
                     VIPNQFEADATAGRDATLSYYYHYALLSVGGEVRGAFETLLRTLSLAPVVVQATAMGL
                     GENQITTFLLPVRSSSHPLFNPDLDYSVYLSNPFFFVFFQVIILLVTVYAIGSEIKFR
                     TGDEWLEAARMNMFVAVVGKLLPYTIIFCIMSVFANYIMFGVMHIPFACGFWPLNLTA
                     ILFVVATQALAVFLFSLFPAIAIVISVVSMVGSLGATLCGVTFPVDSMYAPVHFASYL
                     FPVRHFVEINQNLLYGDYGFPYTWVNVSSLFAFMLLALVLLPHLKTAILSHKYENIR"
     gene            complement(11509..12495)
                     /locus_tag="ACZPB4_10785"
     CDS             complement(11509..12495)
                     /locus_tag="ACZPB4_10785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HIR1098731.1"
                     /translation="MDKTKRYLSVAFVVVLAIVIVVSLIGMILLKKKPVILQGQIEAT
                     EIRISGKLPGRIDTFLVKEGQNVRQGDTLVVINSPEALAKYQQVNAMENIAKYQHQKV
                     DEGTRKQIIASLQQLWNKSKSDLQLAKITYDRVNALYKDSVVTSQRKDEVEAMYKAAE
                     AAERAAYSQYQMAVDGAQIQDKESARSLVTAAQGTVEEVAALLQDARLTAPESGQISA
                     IFPKRGELVGAGMPIMNLVVLDDVHVVLNVREDRLPLFRMGGTFVADVPAIDQKDIEF
                     KINYISPLGSFATWKSTKQTGSYDLRTFEIHALPVEKVEGLRPGMSVLYQLP"
     gene            complement(12530..13972)
                     /locus_tag="ACZPB4_10790"
     CDS             complement(12530..13972)
                     /locus_tag="ACZPB4_10790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HIR1098732.1"
                     /translation="MVSNIVSYSILLLYLLPCASWSQGNDVDLSLEQSLDLLHKENKS
                     LKIAGKEVEWARNEHQKLNAFWYPSVNAAGAFVHMSNPIEVRQSLSKYTEPAKEFVHN
                     YIPDNELIMSVLDKIGQGTFSLPLISQNITSIDATVTWPVFTGGKRIYANKIGKTMVS
                     IAEVNRNQVDANQQSLLIEAYFGLRLGQSVVDVKTEVYNSLKTHYDQALKLEQNGMIN
                     RAERLFAQVSMDEAKRELESARKDLAVAQQAFKSLINMEEGSDVRTTTPLFINEALPP
                     AQYFKDLVPMNNYIVNQLKLQQVVADNQLKIGRSAYVPNIALFGKQTLYADGLDKYLL
                     PRTMVGVGFTWNIFDGLNREKTIRQAKIASQSLRLGKEKAITDLEVGIDKFYSQLQNA
                     LDNVKALDTTIEMSRELVRVRKKSFQEGMATSTEVVDAEVMLAKVKTAFLLAYYQYDV
                     ALINLLSVCGTPEQFHQYKMEGKTEELLGN"
     gene            complement(14034..15233)
                     /locus_tag="ACZPB4_10795"
     CDS             complement(14034..15233)
                     /locus_tag="ACZPB4_10795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008771772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HIR1098733.1"
                     /translation="MEQVSKQQPVNKTAFRVLVALSVTHCLNDSLQSVISAVYPLFKD
                     DLALSFAQIGLITLVYQLSASVFQPITGLIFDKRPVAWSLPIGMSFTLVGLLNLAFSS
                     TLHWVLISVFLIGIGSSVLHPEASRITSLASGGRRGLAQSLFQVGGNLGGSLGPLLVA
                     LLVAPYGRTHIALFSILAFVAILVMIPICRWYKAYLSRVKWQKKSGETHVEMPLSLGK
                     TVFSISILLTLIFSKYIYMASLNSYYTFYLIHKFGVSVQTSQICLFVFLIATAIGTLA
                     GGPIGDKIGRKYVIWGSILGAAPFSLLMPHVGFVWTIVLSFCVGLVLSSAFPAILLYA
                     QELLPYKLGLISGLFFGFAFGVAGIASAVLGNMADHYGIEAVYNVCGFMPLLGLVTWF
                     LPNLKKK"
     gene            complement(15573..16112)
                     /locus_tag="ACZPB4_10800"
     CDS             complement(15573..16112)
                     /locus_tag="ACZPB4_10800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051219 - phosphoprotein binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FHA domain-containing protein"
                     /protein_id="HIR1098734.1"
                     /translation="MKRVFCPKCDNQLSFDETKYPEGKVLAFVCPQCGAQFKIKLGRK
                     VVKTATGEEKEVKEPDFSCGYITIIENGFAFKQDLPLVMGDNVIGRRNKDTEGVDVPI
                     ITSDPSMGRKHCVINVKKDANGKFVYMVRDFPSLTGTFVKNVLVGKKEQVRIGEGTIV
                     TIGATTFILHSANEGEEEE"
     gene            complement(16400..17968)
                     /locus_tag="ACZPB4_10805"
     CDS             complement(16400..17968)
                     /locus_tag="ACZPB4_10805"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing sensor histidine kinase"
                     /protein_id="HIR1098735.1"
                     /translation="MGQCNKMLEEMSFNALFQKLPVGIEVYDERGQLVDLNRTDENLF
                     AISRKDIMGINLFENPNFPEDKIARLKQGEMVVFDCNYEFDNIQTNEYYNIDPKKEGT
                     NLRLSIKCVPLKGEAEDICGYVLMFTDETEEYQKSEKVEELFTKLKTVMRCSDSLLWE
                     YDVKTDKMHIDLDLRVLGNKSRLRASNLTTKKDFCEIVYPEDRERVLVQGFEKIVMGE
                     IGEYSIQYRQLFEGQYVWVRAYAYPYKYDEAGRPAKILYYLMDITDEIAMQDKLRWAE
                     RERQRKEYELVKAKEANRLKSMFLANMSHEIRTPLNAIVGFANILAETKEIEEEEREF
                     YVDIIDKNSELLLQLIEDILDFSKIEAGTFDITKRNFDFKEICEETYAVHALKIPKNV
                     RFVFDRGSQPVTVFSDPKRVVQVISNFLTNAIKFTSEGEIKLAYKVSKDEIRVSVSDT
                     GMGISEEDCRTIFDRFVKLNACKQGTGLGLAICKNIIEKLGGRIGVESTLGVGSTFWF
                     TLPLKEIKENEPKF"
     gene            complement(18110..18760)
                     /locus_tag="ACZPB4_10810"
     CDS             complement(18110..18760)
                     /locus_tag="ACZPB4_10810"
                     /inference="COORDINATES: protein motif:HMM:NF024242.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HIR1098736.1"
                     /translation="MRNVSEDFSAKFIIIPHVLHGDVLSSLRHFDPGFHFFVKDHFYY
                     NIEDNNGIERFQSFCKLIENELERYRGNGLLRERIICYLGIFYMDVYDYYVKVRKKIP
                     FRTSLRKEQLIYDFCSLVAENFKNHKNVGFYADKLNITTTYLSAIMNERCGISAKEFL
                     SIYIVLEVKSLLRDSRLNIQEIAILTNFPSQSTLNRFFRQRTGMTLSQYRKHIFST"
     gene            complement(19672..20361)
                     /locus_tag="ACZPB4_10815"
     CDS             complement(19672..20361)
                     /locus_tag="ACZPB4_10815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098737.1"
                     /translation="MKFALHTSTAISSVLKEPEHFYVDIYYLIILIIVAFTLLLLSFL
                     RYHLYKTKKEKELREIASLVDKNEILIQRYSREMSHIKEQLEAKEKCLKEYQHAAQWK
                     AHRDVESLIKEKERLAKCLLEQLDTFKKLKILSKSETILPDSDWRNLIEIVNTLYDDF
                     ISRLRVAYPDLTEDAIRFCCLIKLRLTSAELMSVLNVTKDAIYKRKFRLKKELMPDDD
                     PRSLDDFLGSY"
     gene            complement(20381..21343)
                     /locus_tag="ACZPB4_10820"
     CDS             complement(20381..21343)
                     /locus_tag="ACZPB4_10820"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009101 - glycoprotein biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HIR1098738.1"
                     /translation="MEVFSIIIPVYNRPEEINDLLNSLTRQTYVHFEVIVVDDGSSIP
                     CEPVVNAYNDRLRIRYFYIENSGPGLARNQGVRYAEGEIVIVLDSDCIVPASYLEQVH
                     ESLMRYKVDAFGGADRAHSSFSAIQKAVNYSMTSFFTTGGIRGSRRHLDTFYPRSFNM
                     GMRKEVYEALGGFSDMRYGEDIDFSIRIFAAGYKCRYFPGAWVYHKRRTNFVQFFRQV
                     WHSGYARIILYQKYPESLKWVHCLPALFVVGLLGVCISAFFVPKVWGLLLFYISLIFF
                     DALVRNKNGIVALLSIIAAFVQLIGYGTGFLEAIWREGILRKKY"
     gene            complement(21589..22464)
                     /locus_tag="ACZPB4_10825"
     CDS             complement(21589..22464)
                     /locus_tag="ACZPB4_10825"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HIR1098739.1"
                     /translation="MKVGIFGSEYQIERQNLIKRLFEKLREQEADIYVDSPFYTFLTD
                     AFGFEPVVSGLLVGDEFDLDIALSVGGDGTFLRTAARVNKQDIPILGINTGRLGFLAD
                     VSSNEVEDTLDEIFKNYYKVEERTLLRLYTEDRAFRGYNYALNEIAVLKRDSSSMITI
                     HTFLNGEYLTSYQADGLVVATPTGSTAYSMSVNGPIIVPQSNSIVLSPVAPHSLNVRP
                     LVIPDSDIITLRVESRNKYFLISLDGRSEIFPAGIELKMSKADYTTKVIKRYNHTFYQ
                     TLREKLMWGADVRMK"
     gene            complement(22480..23139)
                     /locus_tag="ACZPB4_10830"
     CDS             complement(22480..23139)
                     /locus_tag="ACZPB4_10830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HIR1098740.1"
                     /translation="MLVKDFITKEIPVLKSFDTAEYALALMEDFKLKHLPLLSDNAYQ
                     CLVSEKDLLAMLDPSATIGEPVLFAPAISENGHLHEALAMITRYGLSLLPVVSVDGTY
                     LGAITRDRLVDALSELCNAEAAGSVIVLEMMPQDYSLTDIARLVEANNAHVLNLLSHQ
                     DKDTGRLLITLKIDLEDASPVIRSFERFNYTVLYHFMEKGMVDDMLQQRMNELLHYMN
                     M"
     gene            23224..23940
                     /locus_tag="ACZPB4_10835"
     CDS             23224..23940
                     /locus_tag="ACZPB4_10835"
                     /EC_number="2.6.99.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033856 - pyridoxine 5'-phosphate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxine 5'-phosphate synthase"
                     /protein_id="HIR1098741.1"
                     /translation="MTNLSVNINKVATIRNARGGNMPNVLKVAQDCELFGAQGITVHP
                     RPDERHIRYSDVYGLKPLIRTEFNIEGYPCDKFIDLVLKVKPTQVTLVPDAPDAITSN
                     SGWNVKDNFDYLSELVDTFTSQGIRTSIFVGTDLANIELAAKTGTDRIELYTEPYATF
                     YPEDRDKAIAPFVEAAQLAKNLGLGVNAGHDLSLENLAFFNKNIPWLEEVSIGHALIC
                     DALYHGLQETIALYKACLNN"
     gene            23990..>24174
                     /locus_tag="ACZPB4_10840"
     CDS             23990..>24174
                     /locus_tag="ACZPB4_10840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MotA/TolQ/ExbB proton channel family protein"
                     /protein_id="HIR1098742.1"
                     /translation="MSILLSLQAVGSQTADQMPDLTAVAVPTEAEINVIDLAFKGGWI
                     MVVLLLLSLMAIYIFVQR"
BASE COUNT         7041 a         6008 c         4899 g         6126 t
ORIGIN      
        1 gttttattac actttaatat aataaattag cgattatgat ttattcacat gaagttcaac
       61 acatgtgtgt tgtaaagaag ggagctaacc accagtgcgc tccgattcct gaagaaggaa
      121 agtgggttag agcaactcag atcactgata tctctggttt gactcacggt atcggttggt
      181 gcgcgccgaa acaaggtgga tgtaagctga cattaaacgt taaagaagga atcatccaag
      241 aggctcttgt agagacaatc ggttgttccg gtatgactca ctcagcggct atggcttctg
      301 agatccttcc gggtaaaact cttttggaag cattgaacac agaccttgtt tgtgacgcta
      361 tcaacaccgc tatgcgcgag ttgttcttgc agatcgtcta cggtcgtaca cagtccgctt
      421 tctcagaggg aggtctgcct gtaggcgctg gcttggaaga ccttggtaaa ggtttgcgta
      481 gccaagtggg tacgatgttc ggtacattgg ctaaaggtcc ccgctacttg gagatggccg
      541 agggatattg cacgcgcatg gcattagacg ctgatgacga agtaatcggt tatgaattca
      601 tccacttggg taaattcatg gatatggtta agaagggtat ggacgctaac gaggcactgg
      661 aaaaggcgaa aggctcttac ggtcgtttca aagaagctgt aaaatatatc gatcctcgta
      721 atgaataaga aaacatttac acgtgtcctc atcgggctga gtgttatcac ggctgtggct
      781 acgcttatca cgtatttcgt gatgaagccg gagaaaccgt ggttggcgtt ttacgtggct
      841 tgttgtggcg gtgtattggt tttcaacttt ctgatatctt tattcctagt aaataagaat
      901 tttaaaaagt aaaaaaataa tatggcttta tttgaaagtt atgaccgtcg tattgatcat
      961 atcaacgcgg tattaaacga atatggtatc aacggtatcg aagacgcaaa ggctatctgc
     1021 gatgctaaag gtatcgaccc ttatacaatg tgtaaggaaa ctcaaccgat ctgtttcgag
     1081 aacgcttgct gggcttacgt agtaggtgcc gctatcgcta tcaagaaagg ttgtacgaac
     1141 gctgccgagg ctgccgaggc tatcggtatc ggtttgcagg cattctgtat cgctggttct
     1201 gttgcggatg accgtaaggt gggtatcggc cacggtaact tggccgctcg tttgcttcgc
     1261 gaggagacta agtgtttcgc tttcttggct ggccacgagt ctttcgccgc agctgagggt
     1321 gctatcaaga tcgccgagat ggcaaacaag gttcgtaaag agcctttgcg tgttatcttg
     1381 aacggtttag gtaaggatgc cgctaagatc atctctcgta tcaacggttt cacgtatgta
     1441 cagactcagt tcgactacat gacaggtgag gtgaacgtta tcgaggagaa agcttactct
     1501 aacggtcttc gtgcgaaagt taagtgctac ggcgctgacg acgttcgtga gggtgtagct
     1561 atcatgcgta aggaaggtgt tgacgtatct atcacgggta actctacgaa cccgactcgt
     1621 ttccaacacc cggtagccgg tacttataag aaagaatgta tggagaacgg tcacccgtat
     1681 ttctctgttg cttctggtgg tggtacgggc cgtactttgc acccggacaa catggccgct
     1741 ggtcctgctt cttatggtat gacggacaca atgggccgta tgcacggtga cgctcagttc
     1801 gctggttctt cttccgtacc tgctcacgta gaaatgatgg gcttcttggg tatgggtaac
     1861 aacccgatgg taggtgctac ggttgctgta gcggttgcta tcgaggaagc tatgaagaag
     1921 taatcaacta aacaataaaa taattgttta tatatagact cctgtaatct tgatggttgc
     1981 aggagttttt attttactta tcaaaaggag gaaaaggatg acactaaaca tagaccaaga
     2041 gagttgcatc aaatgcggga aatgcgtacg ggtatgccct tcggatatat tcacgcaaga
     2101 aagggccgga gagacgatcg ggctggtacg tgtggaaagc tgcatcgttt gcgggcattg
     2161 cgtggacgta tgtccgaccg gttccgtgct acacagcgaa ttcccgccgg agaaaacgca
     2221 tacgatcgat tacagccaga tgcctacgcc ggagcaggtg atgttgctga tcaagtcacg
     2281 ccgttccaac cggacattga cctcgaggcc cgtccccaag gagatgctgg acaagatcgt
     2341 ggaggccgct cattctgcgc cgacggctac aaactcccaa agcctttcgt ttaccgtcgt
     2401 caccgatccg cgaaagctac ggcaggtgag cgattatacg ataggcgtgt tcgactcctt
     2461 ggcgaagcta ttattgaatc ccgtcgtgaa atgtgtggtc aagccgttta tgaaggatgt
     2521 ctataaatac gtaccggtat tcaatcggtt gaaagaggaa cacaaggcgg gtaaagatcc
     2581 gattctccgg aaagccaccg ccctgctact gatccataca ccgaagtcca accgattcgg
     2641 aagtgaggac gctaacctcg cttatcagaa cgcctccttg atggcgcaat cgcttggggt
     2701 aagccagatc tatatgggct ttgtgctcac cgccatccgg caggaaggaa aagatacgct
     2761 cgccgagacg ctagggatcg acggcaagat acaagcgatc atggcactcg gcataccggc
     2821 tttcaagtac ccgaagtata cggaccggaa agagatcgtc aagaactata tcgagtgaga
     2881 cttgatggag acaaccttgt cgaccggggt atgcgatcca ttggattacg catcgtaagt
     2941 caatggatta cgatacgtaa gtcattgact tatggttcgg atctcatagg tttaccgggc
     3001 taggatcact cccgatcacc agaacttatt atgctccggg ctgtattcaa aaccagcgtc
     3061 tttaagcttt gtaagaaggg atttcttgtt cacttgcaaa tcctcgcata aatcgtcgag
     3121 ggaagaataa ttgtcacgaa gtttcatatt gatgaagctg aatagcatca tcggatcgtt
     3181 tggtaatgac ataatcttac gaataaaaat gttatctatg ttttacaaca caaagataat
     3241 gctttttcgc cagatggaac ccagacacga tccttattat ttgaatatcg gtacgcaaca
     3301 aaacaaccta caaactggtt ttaaataacg agaacttata attcaattga atgacatgaa
     3361 aaaatatgta ttagtagtag cggtagccgc agccctattc agctgtagcg gcaacccaaa
     3421 ggcagacgcc acgcaaacag acaagaacaa gcaggaaacc gcccaagtac cggatatgca
     3481 caacgcagag acttccttgg attactgggg tgtttacgaa gggacattac cggccgccag
     3541 ctcgccgggt attaaaacga ccttgacatt gaacaaggat aaaaccttta ccctccgctc
     3601 cgaatatatt gacgagaaag acggtatttt taatgataag ggaacttaca cgctggacgg
     3661 taacatcttg acggcgaaac aagaaggggg agacatcacg tattataagg tagaggaagg
     3721 ccaactgaaa atgctggacc agcagaagca acccgtcacg ggcgacttag ccaagttcta
     3781 tatccttaag caaacaaaga aattctagga tttatcccca taagtatata ctttcaaggg
     3841 caaaagcata cccttttgta catgaaagta tatactcatt tgcctaaacc caaaactatt
     3901 cctacctttg cgtccctata taactatata attactccaa tgagaatagc cgcttaattt
     3961 atctcaagat gtcgttcttt ccatccggaa agccctctat ccgtatagag ctgatttcgt
     4021 gacgacagat tcgaggctat cgtgaaaccg atcatcatcg gtatttctta tccattttag
     4081 tatctcacat tttaaatcag ttcacactat gagtatcgta gcgcaaaaaa tcacgtatat
     4141 acatccggac aaccaagtct tattcaaggg gatcgactta acgatcaaca aggggcaaaa
     4201 ggtagcctta gtcgggaaca acggatcggg aaaatctact ttcctccgta tcttggctgg
     4261 aaccttgcaa gcgcaggaag gggagattat ctatccgacc ccaccctatt acgtacccca
     4321 gcatttcggg caatatgata accagacggt ggctcaggcc ctacgtatcg acgggaaact
     4381 agaagccttg cgggcgatta ccgagggcga cgcctccctc tctaatttca atacgctggc
     4441 ggatgactgg acgatcgagg aacggagcct cgccgccctg cacgcttggg gtttggagca
     4501 tatcctcctt tcccaaccga tgcgcacatt aagcggaggc gagaaaacca aggttttcct
     4561 ctccggaatc gagatccacc aaccctcgat cctgctattg gatgagccga ccaaccatct
     4621 ggataggcgt agccgggaga agttatacga tttcatcacg tcttgccgta tcaccttgtt
     4681 ggtcgtcagc cacgatcgta ccttattgaa cctattagct tccatagcgg aattatccgt
     4741 cggggggatc accctttacg ggggtaatta tgatttctac aaggaacaaa aagaacagga
     4801 acaggcttcc atgcaagaga aactggaagc gaaggagaaa gagcttcgca gggtcaggaa
     4861 aaccgcccgt gaggtagccg agcgaaaaca aaagcatgaa tcccggggag agaagcaaag
     4921 cgtccggaaa ggaatccccc ggatcatgat gggcggattg aaggagaacg ccgagaaaag
     4981 cgcctccaaa ctaaaagagg ttcacgagga caagatggag aaccttgcca acgagctaaa
     5041 gcgaatgcgc tcctccctac ccgaccttca aggcatgaaa ctggatttca gcgcatccgg
     5101 cttacacgaa ggcaagatat tggttaccgc caaggagatc aatttcggtt acgccgaggc
     5161 cggcgatcta tggccctccc cgatgagctt ccagatcaag agtggggaac ggtggctgat
     5221 acaaggcgat aacggttcag gcaagacgac tttgctgaag ttgattaccg gccagttacc
     5281 gcctcgtagc ggttccttga tccgtgcgga tttctcctct atctatatcg accaagaata
     5341 ctcgatcgtc cggaacgacc ggacggtgta cgagcaagcg caagccttca acgagcgtca
     5401 tttccaagag cacgagatca agacattgct aaaccgtttc ctcttcccgc acgacacgtg
     5461 ggagaagagc tgcgggaagc tgagcggagg cgagaaaatg aggttggcat tctgttgctt
     5521 gatgatcagt aaccagactc cggacctgtt tatcctagat gagccgacca ataatctcga
     5581 catccaaagc atcgagatta tcacctccat ggtccgtgcg tacaggggca cgatcttgct
     5641 gatctcgcac gacgcttatt ttattcggga attgggtatc caccaaataa taactacctt
     5701 cgcgggtagg ttaaagacga atttatgaag acgttacttg acgtgcatac ccatacggta
     5761 gccagtgggc atgcctttag caccctgcaa gaaatggcag tggccgcctc cgagaaagga
     5821 ttgaagttac taggtataac agagcatgcc cccggcatac cggggacatg ctccccgatt
     5881 tacttccgca acctacatgt ggttccccgc cggatatacg gtgtcgagtt attgctcgga
     5941 gcggaattga acatcatcga ctataagggt acgatcgata tgggcgagga gtacttcccg
     6001 atgctggata tccggatagc aggcatccac tcgctttgct acaaaccggg aacggtcgag
     6061 cagaatacgg aggcgatgat cggggcgatc cgcaacccgc atgtccacat catcagtcac
     6121 ccgggagacg gtacggccga ggtggatttc gaacctatcg tattagcgtc caaagagcat
     6181 cacacgttgc tggagatcaa caacagctct ctcaacccgg tccgcaagaa actcaccgcc
     6241 agagataata acctcacgat cttgcgccta tgcaagaaat acgaggttcc tgtgatttta
     6301 ggtagcgatg cgcatatatc tttcgatata gcccggtacg atcatatcta cgagttattg
     6361 caagagacac gatttccgga ggaattgata ttgaacgaca aggtagaggc nnnnnnnnnn
     6421 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     6481 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn acttacaatg ttcctttatt aatttgtcca
     6541 cgacaggatc acccaactcc ttcgccttgt tgaaagcctc gcacgcttcc gccttcttac
     6601 cctgacggac gtagcagatg cctcgcagac ggtagcaaga ggcgaaatcc ggagcgatcc
     6661 gcaaggcatt ctctaagctc ctcaacgcct gatcatagtt ttccatacgg atatatacgg
     6721 acgcttcctc cgccggataa gtcgggtcgc ccggattcaa gcggatcgcg gattggatat
     6781 cggccaaggc gccggggaaa tcgttcatgc ggaacttcgc ttgctcgcgg taatagaaga
     6841 agcggtcgcc gacctgtcct ttcaagagat cgtagtataa atcataatcg tccacggcct
     6901 ccttgtattg catcagtttc aagcggagat ccacccgttc caagatatag ggagcggcct
     6961 cgttcgttgg cgggttcccg catttggcga tggcgctatc cagcaaggcg atgatatccc
     7021 cgaagttagc gccccggata ttcgccttcg ccttcgccgc ccaataccaa gaggtagagg
     7081 atgccatatc gctatcgttc accttcatat aatcatcgaa cgcctgctcg aaatctcctt
     7141 tataaaaatg gatgtcccct tccaattggc gatagaccgg caagtcctcc tccccgatcg
     7201 ccttttgtat cgcctcggta gcggcatcga cagtccactg ctccttattc aaggtcgtat
     7261 ccgcgacggc cacgccgtag atcagcttgg ctcggttgaa ccagacatcc cctttccgct
     7321 cgctgaagcg ggaagccgtg tttatatctt ccaacgcctt atccagacaa gccccctgct
     7381 cggcctccgt aggagccaga tccgcacggt ggtaagcgta atgattggca cggttcaaat
     7441 acccgtcggg agaatccggg aaagtggcga tgaaatcatt caaggtagcc agatacgtct
     7501 ttgggtcttg cgagcttgcc atcagatata aggaaacctg cgcttggctc acgtccgacg
     7561 gccacgcctt ccggatacca atccggctat aggtggaatt aaaggcgtcc gccgactgga
     7621 tcgtcaggct attcgcgtat cccgccgaga ccgcatagga atcttctttc ttccccgacg
     7681 catcttcctg cgccaagccg aacacctcgc cgtccgccgt caatacagga gcgtttacct
     7741 gcccgctttc cagcgccatc gacaatttat aatagctgaa cggctccttc aacttactga
     7801 cctccgagac cggtccttcc ccgaacttcg tgatcttacc ggtcgagtaa ggcatcagat
     7861 aagcgataac tccttgcgag atcggctcac gggcgatcgg caagaacaca gctttcttcg
     7921 gaacctctac cttgaacttg atcacgtcat ataattcatc agcccccaag atgcggctta
     7981 ccggatattc ttttccgtcg gcgtcggtca cggtcgccct cgccgcatcc ttaaacaagg
     8041 aatagccgga caacgcctca ccggtctcgg taatgaaaaa tcccgtaccg gacgctttct
     8101 tctggttatc ttttccataa gtagtgacgg taaccaccgc ctttcgttgc ttatccatcc
     8161 atttgggcgc tttcttttgc gccgccaccc aaaatacttg gcaacaaatc gtaatcaaca
     8221 gaacaattct tctcatttcg ttttcatgtt atcagaatat acgtcgcaaa tgtaaatatt
     8281 tataccggat aggcgaacaa attagggaat taatctatta tgagtatatt cgcggaaaca
     8341 cttataaaaa accgcgagat tatgagacta aaatcatgta tgcttatgtg tagtttattc
     8401 atggcgagct tagcctccgc tagtaacttc gcctcggatt ctttcaagac caagagcgga
     8461 aaagaactga tcatcacgtt catcaagcac ggtagcttga tgcttacgta cgacaatcat
     8521 tcgatacagg tagatcctgt ctccgaatac gccgattata cgactttccc gaaagccgat
     8581 atcatcttga tcacccacga gcatggcgac catctggacc cgaaagcgat acaagccgtc
     8641 gagaaaagcg gtacggaaat catcgccaac gagaacagcc aaaagaagct gggaaaaggg
     8701 aaggtcctaa aaaacggcga tacggatacc tccatcagct atatgaagat agaggccgtc
     8761 cccgcctata acaccacgcc cggccgggat aaatatcacc cccgccaccg ggataatggc
     8821 tatatcctca cgttcgacgg actaagagtc tatatagccg gcgatacgga agacatcccg
     8881 gagatgaaag acctgaaaga catcgatatc gctttccttc ccgtcaacca gccttatacc
     8941 atgaccgtcc cgcaagcggc gaaagcggcc cggatgttct cgcctaaaat cttataccct
     9001 taccattacg ggaatacgaa gatcggcgag ttgaaagacg ccttgaaagg tagcggcatc
     9061 gacgtgagga tacgggagct acaatgacga caaggcacgg ctcgccttta agatattccg
     9121 ccggtacacc cagcaagcca agaggaaata aacgacgctt tgcacccaca acgtcacgta
     9181 ctccacaccg acttgctcaa tcgacgctcc catcgagttg agctgtacat aggccagcgt
     9241 ggcgggagcc gccggaatga tataatgggc catttgccaa taccaaggca tcaattccaa
     9301 gggataagag actccggaaa ggaagatcaa gcctaccgag aagaaggcga tcatcaataa
     9361 cggagcctcc gagtccgtaa agaaataaga ggcggccagc ccaaagaagc tggtagccag
     9421 caagaaaggt atcagcagga tcaaggtgtt cagataatta ccgatatccg gcaggccaaa
     9481 caatagcggt atcaagccca acaagaacaa agcgaaaatc atatacaata cgcaatacac
     9541 aaaggtcttg ctgattatca ccctagcgat ccggccaaag gataatccct cggaggcgaa
     9601 acgaacgatg gtacccgaat cccgctcttc cccgcttatc ataccgatca ccatcaacaa
     9661 ggtctggaac ataatgacga tcaataccgc cgggatcaaa taggttccat atccttccgt
     9721 aaaattatac aacgccgtcc cgaccactga tatgggttgc gccgaaacga tcttggaagc
     9781 gtcttgctgg ggcaagaaca ccaacatctc cggacgatac cgatcgttca acgccaacat
     9841 ggcaccgctg gaagcctcct gcatcgccat ataatatagg aaggcgcttg tcgtctggta
     9901 catgataaac agggactcat tccctcgtgc cacccgggtc tcgaaatcag agggaagata
     9961 caagatacct acggcatccc cctccttcat ccactcctgc gcctcagcgt aatctaaacc
    10021 atcggcgatt accgagactt gcggagtggc gttcagtaaa cggatgtact cccggctcaa
    10081 gtcggtcttt gagtcatcga cgactaccac cggggcgtta cgcaccagat ccggggcata
    10141 catataatta tacagcaggc catagagaaa tatacctcct accaagacga gcaagatagc
    10201 gtagctcgtg gagatcgtct taaactcgtc cttgaccaag gaagcgatat ccgccaaggt
    10261 tcctttcata ttatcggatg ttctcatatt tatgacttaa aatagcggtt ttcaaatgtg
    10321 gcaacagcac caatgccaat aacataaacg caaacaacga acttacgttt acccatgtat
    10381 aagggaatcc gtaatcgcca tacaataagt tctggttgat ctccacgaaa tgccgtaccg
    10441 gaaacaggta cgaggcgaaa tgtacgggag cgtacatgga atcgaccggg aaagtaacgc
    10501 cgcataaagt agcccccagc gaaccgacca tagacaccac gctaatcacg atcgctatag
    10561 cgggaaacaa cgagaacagg aataccgcca acgcttgcgt agcgaccacg aacaagatcg
    10621 ccgtcaagtt caatggccag aaaccgcaag cgaaaggaat atgcatgacc ccgaacatga
    10681 tatagttagc gaagacgctc atgatacaaa agataattgt ataagggagc agcttgccca
    10741 ccaccgccac gaacatgttc atccgtgccg cctccagcca ctcatcgcct gtccggaact
    10801 tgatctcgct accgatagcg tacaccgtaa ccagcaaaat gatcacttgg aaaaagacaa
    10861 agaaaaaagg attgctcaga taaacggaat aatccagatc cgggttgaac agcgggtggc
    10921 tactggatcg taccggtaat aggaaggtgg ttatctgatt ctcccccagc cccatcgccg
    10981 tagcttgcac aaccaccggg gcgagcgaaa gcgtacgcag cagggtctcg aaggccccac
    11041 gtacctcacc acccacactc aacaaggcat agtggtaata atacgataaa gtagcgtcac
    11101 gccccgccgt ggcatccgcc tcaaactgat tggggatcac tagataaccg tagatttctt
    11161 ttgcttgggt agcacggcga gcggtctctt ggtccgtata atgccgggtt acccggaaag
    11221 tcggtaccgc ctctacctgc cggatgatct cccgagacat ggaggtgttg tcttggtcca
    11281 ctaccgctat cggtatattc tccatctgcc cgcttccgaa aatcgtagac atgaagaata
    11341 tacagaacaa aggcaacacg atacacaccc cgaaatataa cctccgggaa accatgcgat
    11401 ccagttcccg acgtaaaacc atatagaaag gactcttctt tagcatagcg acaataaatt
    11461 atttagttgt agagacggag cgtgcttcgt ctctacaact ggatagtatc aagggagttg
    11521 atagagtacg gacataccgg gacgcaatcc ctccaccttc tccaccggca aggcatgtat
    11581 ctcgaaggta cgcaagtcat agctacctgt ctgcttggta gatttccaag tagcgaaact
    11641 gcccaacgga ctgatataat tgatcttgaa ctcaatatcc ttctgatcga tcgccggtac
    11701 atcggcgaca aacgttcctc ccatcctaaa taaaggtaaa cgatcctcac gtacgttcaa
    11761 taccacatgc acgtcatcta atacgactaa attcatgatt ggcatcccgg ccccaaccaa
    11821 ctctccccgt ttcgggaaga tagcggagat ctgtcccgat tccggagccg tcaaccgagc
    11881 gtcctgtaag agagccgcca cctcctccac ggttccttgc gccgccgtca ccaacgagcg
    11941 ggcgctctcc ttatcttgta tctgcgcccc gtctaccgcc atttgatatt ggctataagc
    12001 ggcacgttcg gcggcctcag ccgctttata catggcctcc acctcatctt tacgctgtga
    12061 ggttaccaca ctatctttat acaaggcatt cacccgatca taggtaatct tcgccaattg
    12121 taaatccgat ttggatttat tccacaattg ttgcaaggaa gcgatgattt gctttcgtgt
    12181 accctcatcc actttctggt gctgatactt cgctatgttc tccatggcgt tcacctgttg
    12241 atatttagcc aacgcctccg gactattgat gactaccaag gtatcgcctt ggcgtacatt
    12301 ctgtccctct tttaccagaa aggtatcgat acgccccggt aacttaccgg agatacgtat
    12361 ttccgttgcc tcgatctgcc cttgcaagat caccggcttc tttttcaaca agatcatccc
    12421 gatcaacgag acaactataa caatcgccaa gaccacgaca aaggccacac tcaaatatct
    12481 cttagtttta tccataaccc ctaaattttc aattttcaat tctcaatttt caattcccca
    12541 aaagctcctc ggtctttccc tccatcttgt attgatggaa ctgctccggc gtaccgcaga
    12601 cagacagcag attaatcaag gctacatcat actgataata agccaaaaga aaagcggtct
    12661 tcaccttcgc cagcataacc tcggcatcga ctacctccgt agaagtagcc attccctctt
    12721 ggaaagattt cttccgcacc cggaccagtt cccggctcat ctcgatcgtc gtatccaaag
    12781 cctttacgtt atccaaggca ttttgtagct ggctgtagaa tttatcgatg cctacctcca
    12841 gatccgtaat cgccttctcc ttacccaaac gaagcgactg actagcgatc tttgcctgcc
    12901 ggatggtttt ctcccgattc aagccgtcaa agatattcca cgtaaaacca actcccacca
    12961 tcgtacgagg caacaaatat ttatccagtc catcagcgta caaagtctgt ttgccgaata
    13021 aagcgatatt cgggacataa gcggaccggc cgatctttag ttgattatcg gctacaacct
    13081 gctgcaattt caattgattg actatataat tattcatcgg aaccagatcc ttgaagtatt
    13141 gggccggagg aagcgcctca ttaataaata aaggagtcgt ggtacgtacg tcactcccct
    13201 cctccatatt aatcaagctt ttaaacgcct gttgagcgac cgctaaatcc ttacgggccg
    13261 attccagttc tcgtttcgcc tcgtccatac ttacctgagc gaacagacgc tcggcccgat
    13321 tgatcatccc gttttgctct aatttaaggg cttggtcata atgggttttc aaagaattgt
    13381 acacttctgt ttttacgtcc accacacttt gtcccagacg aagcccgaaa taagcctcga
    13441 tcaataagga ttgttggttg gcatccactt gattcctatt cacctccgct atagagacca
    13501 tcgtctttcc gatcttgttc gcatagatac gttttcctcc cgtgaaaaca ggccacgtca
    13561 ccgtagcgtc tatagaagtg atgttttggg agatcagcgg aagcgagaaa gtaccttgcc
    13621 ctatcttatc caataccgac atgatcagct cattatccgg gatataatta tggacaaact
    13681 ccttcgccgg ttccgtatat ttactcagcg actgccgtac ctctatcgga ttcgacatat
    13741 gtacgaaagc acccgcggcg ttcaccgacg gataccaaaa agcgtttagc ttttgatgct
    13801 cattccgagc ccattccact tctttccctg ctattttcaa gcttttattt tccttatgaa
    13861 gcaggtcgag agattgttcc aagcttaaat ccacatcgtt cccttggctc catgaagcgc
    13921 atggaagaag atacagcaaa agaatactgt aagatactat attactcacc ataaactcat
    13981 ttagtaattg acgttcagtt ggagtaataa cagcgaaaaa gggaggattg tttttacttc
    14041 tttttcaagt tgggaaggaa ccaagtaacc agtcctaaaa gaggcatgaa gccacataca
    14101 ttgtagacag cctctattcc ataatgatcc gccatatttc ctaatacggc cgaggctata
    14161 cccgccacac cgaaagcaaa tccaaagaaa agtcccgaga taagacctaa tttataagga
    14221 agcaactctt gcgcatacaa caaaatagcc gggaacgccg atgataagac caaacccacg
    14281 caaaaactaa gcacgatcgt ccaaacgaat cccacatgcg gcatcaacaa gctaaatggg
    14341 gctgccccta gaatcgatcc ccaaatcaca tatttccgtc ctatcttatc accgatagga
    14401 ccacccgcca aggttcctat ggccgtagcg atcaggaaga cgaacaaaca gatctgcgaa
    14461 gtctgtacac tcaccccgaa tttatggatc aagtaaaagg tatagtagct attcaaacta
    14521 gccatataga tatatttaga gaaaatcaag gtcagcaata tcgagatcga aaagactgtt
    14581 tttcccaaag aaagaggcat ctccacatgc gtctcacccg acttcttctg ccatttcacc
    14641 cgactcaaat acgccttata ccaacggcag ataggaatca tcaccaaaat agcgacaaat
    14701 gctagtatag aaaacaaagc gatatgagtc cgtccataag gcgccaccaa tagagcaacc
    14761 agtagcggac ctaacgatcc gcccaaatta ccacccactt gaaaaagcga ttgcgccaat
    14821 cccctacgcc ctcccgacgc tagcgaggtg atccgggacg cttccggatg caaaaccgaa
    14881 gacccgatac ctatcaagaa tacggagatc aagacccaat ggagcgtaga ggaaaaagcg
    14941 agattcaaca agccgaccaa cgtaaaactc ataccaatag gtaacgacca agccacggga
    15001 cgcttatcaa aaatcaaacc ggttataggc tggaaaacag aagcggataa ttgataaaca
    15061 agcgtaatca acccgatttg ggcgaagctc aacgctaaat catccttgaa aagtggataa
    15121 accgccgaga taacggattg caacgaatca ttcaaacaat gcgtaacgct taacgccacc
    15181 aatacccgga atgctgtttt atttaccggc tgttgtttag aaacctgctc cataactatc
    15241 tatatttcta tttcacctcg tgctcattaa catttcaaaa accgcacaaa aagttagcta
    15301 atttctagaa aaacaaaccc taagagccta ttttaactat agttaataca actattcttt
    15361 cggttctttt catttcttta tgttaatcgg cttaatctta atacctatga gccttgtttt
    15421 ctcagtgata cttcagagct gtatcccgga atgagcatat atcttataac tcactcccaa
    15481 aacaaacgcc aaaatccctt atctgccatc attccgaccc gaagttaaag atcgagatca
    15541 ttaacgggaa cagcctctga agttttttat atttattcct cttcttctcc ctcgttcgcc
    15601 gaatgtaaga taaaagtagt agcgccaatc gttacgatcg taccttcccc gatacgtact
    15661 tgttcttttt taccaaccaa cacatttttc acaaaagtcc cggtcaagct aggaaagtca
    15721 cgcaccatat aaacgaactt gccattagcg tctttcttta cattaatcac acaatgctta
    15781 cgccccatac ttggatcgct cgtgataata gggacatcta caccttccgt atccttatta
    15841 cggcgaccaa tcacattatc tcccatcact aatggtagat cttgcttaaa agcaaaacca
    15901 ttctcgataa tggtaatata accacaagag aaatccggtt ccttcacctc tttttcctca
    15961 ccggtagccg tcttcaccac ctttcggccc aatttaatct taaattgcgc tccacactgc
    16021 ggacagacga aggctaatac cttcccttcc ggatatttgg tctcatcaaa agacaactga
    16081 ttatcacatt ttggacagaa tactcttttc atacacttaa atacaggatc tagtattaca
    16141 aacggagcgc aaatttacga aaaaaccttc agctacactc ctaaaatctc atggttatga
    16201 ttttttgaaa caaaaaaggc catccgtcac ggacagccaa tctcaattgt taaccttaaa
    16261 tctaatacca tgaaaaacac agtgcaaata tagaggtttt atgttatgta gcataatatt
    16321 ttatttgcaa atctcattta cttaaccaga tttaacaaaa ctatgcttta aaacatatcc
    16381 gtaaacaata tatatcccct tagaacttag gttcattctc tttaatctcc ttcaaaggca
    16441 aggtaaacca aaaagtggaa cctactccca atgtagattc taccccgatt cgtcccccta
    16501 gtttctcgat aatatttttg caaatcgcca atcctaatcc ggtaccttgt ttgcaagcgt
    16561 tcaacttaac aaagcgatcg aatatagttc tacaatcttc ctccgagatt cccattcccg
    16621 tatccgagac cgaaactcgt atttcatctt tcgatacctt ataggctaat ttgatctcac
    16681 cttccgaagt aaacttaatc gcatttgtca agaaattaga aataacctgc acgactcgtt
    16741 tcggatctga aaaaacagtc acgggttgtg agccccgatc gaaaacaaat cgaacgtttt
    16801 tcggaatctt caaggcatgt accgcatagg tttcctcaca gatctcctta aaatcgaaat
    16861 ttctcttcgt aatgtcaaag gttcccgcct caatctttga gaaatcaagg atatcctcaa
    16921 tcaattgcag aagcaattca ctattcttgt caatgatatc cacataaaac tctcgttcct
    16981 cctcctctat ctccttggtc tctgccagta tattcgcgaa accaacaata gcatttaaag
    17041 gcgtgcggat ctcatgactc atattcgcca agaacataga cttaagccga ttcgcctctt
    17101 tagccttaac taactcatat tctttccgtt gacgctctcg ttccgcccag cgcaatttat
    17161 cttgcatggc gatctcatcc gttatgtcca tcaagtaata aaggattttc gcaggtcttc
    17221 ccgcctcatc atatttataa gggtacgcat acgctctcac ccaaacatat tgcccctcaa
    17281 aaagctgtcg gtattgaata ctatattcac cgatctcacc cataacaatc ttttcaaagc
    17341 cttgtacaag taccctttcc cgatcttccg gatatacgat ctcacaaaaa tcttttttcg
    17401 ttgtcaagtt acttgctctc aatctggatt tattacctaa aacacgtaaa tccagatcga
    17461 tatgcatctt atcggtttta acatcatatt cccacagcaa ggaatcactg caacgcataa
    17521 ccgttttcaa cttcgtgaac agttcctcta ctttctccga cttttgatat tcttccgtct
    17581 catccgtaaa cattagtaca tatccacaga tatcttcagc ctctcctttc aacggcacac
    17641 atttaataga cagacgtaaa tttgtacctt ccttttttgg gtctatgtta tagtactcat
    17701 tcgtttgtat attatcaaat tcataattac aatcgaacac aaccatttct ccctgtttca
    17761 gacgagcgat cttgtcctct ggaaaattag gattctcgaa aagatttatt cccataatat
    17821 ccttccggct tatagcgaac aaattctcgt ccgtcctatt gagatccact agctgccccc
    17881 tctcgtcata aacttcaatt ccaacaggta atttctggaa tagggcatta aagctcattt
    17941 cctctagcat tttattacat tgtcccatcg tcatattaaa ttataaccac taattcccta
    18001 ctttaaatca atcaagcaat ctcctctgtt atttatacaa caaatgaacg ataataacga
    18061 ttgcagcaga agtttaaagt tatagaaata atatgaaaat caaacataat catgttgaaa
    18121 atatatgttt tcgatattga gaaagagtca ttcccgtccg ttgacgaaag aagcgattca
    18181 atgtcgattg agacggaaaa ttagtcaata tagcgatctc ctgtatattt aatcgagagt
    18241 cacgtagcaa cgactttacc tctaacacta tatagataga taaaaactcc ttggctgaaa
    18301 tgccacacct ttcattcatg atcgcactta aataagttgt cgttatattc aatttatccg
    18361 cataaaatcc gacattcttg tgattcttga aattctctgc cacgagacta cagaaatcat
    18421 agatcaattg ctcttttctc aaactagtcc tgaaagggat tttcttacgc actttcacat
    18481 aatagtcgta aacatccatg taaaaaatcc ccaagtaaca tataatccgc tccctcagaa
    18541 gcccattacc ccgataccgc tcaagctcat tctctatcaa tttgcaaaat gattgaaaac
    18601 gctcaatacc attattatcc tctatattat agtaaaaatg atccttcacg aaaaaatgaa
    18661 atcccggatc aaaatgacgt aaggaactta atacatcccc atgtagtaca tgtggtatga
    18721 tgataaactt cgccgagaag tcctcactca cgttccgcat tgagcataac tgtctcggaa
    18781 ataagaaaat caattcattc ttattccata catgcttatt atcaagcaaa tgaatgatcg
    18841 cactacctct attacatact gctattatcc cgtaatccaa aaaagaaggt tctgaagtca
    18901 atggactatc ttcaatctgt tccgtaataa taaagtcttt ttctaatccg cctaaaaaac
    18961 gatcacatgt attataccta ttctcttgca tatactctta taaattaagg gaatacgaaa
    19021 tcttacctcc aacaacaatc aacagaataa tattatattt tgttctgtcc gttaaggtcc
    19081 caagtatatt cgtttgatat ttttctttcc ttaccccctc ttctattagc catcaaacct
    19141 tatatatcaa ttggtgctaa cagctaacca aggaaatcat aaaaaaacac aagacaaaat
    19201 tatataataa aaaattgact attaaatgca taactaaact aaaagcgtac aaaaacacat
    19261 caattgtata caaaatcgaa acagacaaag aataaccgaa aaagatcata aaaatacaat
    19321 tagcttcatt gacaaagtaa gttagctgaa ataccaaagc aagttaactt actttgccga
    19381 tgaaattagc ttactttgaa agtatggatg ttaccctcgg aaaggggcgc ttaagcagtg
    19441 ttctcaaaaa ttcgtgtatt catgcctcta tacaaaaaaa ggctatccgt cacggacagc
    19501 caatctcaat tgttaacctt aaatctaata ccatgaaaaa cacagtacaa atataggtgg
    19561 ttttatgtta tgtagcatac tgaattattt gcaaaattca ttcgcttaac tcgatttaac
    19621 gaaatcatgc cctaaaacat agttattaac aagaaaacta ttcgttcaga tctaatagct
    19681 tcccaagaaa tcgtcgaggg aacgaggatc atcatctggc atcaattctt ttttcaaacg
    19741 aaatttgcgt ttatagatag cgtccttcgt cacattcaag actgacatca gctccgccga
    19801 ggttagccgc aatttgatca agcaacaaaa acgaatggca tcctctgtca aatccggata
    19861 agcgacacgt aaacgactta taaaatcatc ataaagagta tttacgatct cgatcaagtt
    19921 tctccaatct gaatccggca atatcgtttc cgatttagaa agtatcttca gcttcttgaa
    19981 cgtatccaac tgttccagca aacacttcgc caaacgctcc ttttccttga tcaaggattc
    20041 cacgtcacga tgcgctttcc actgagccgc atgctggtat tccttcaaac atttctcctt
    20101 cgcttccaat tgctccttga tgtgcgacat ctcacgacta taacgttgta tcaagatttc
    20161 atttttatcc acaagactcg ctatttctct cagttctttc tccttttttg tcttataaag
    20221 gtgataacgc aaaaaagata acagaagcag ggtaaaagcg acgatgatta aaatgatcag
    20281 ataataaata tctacataga aatgctccgg ctcctttaga accgagctta tggcagtaga
    20341 tgtgtgcagc gcaaacttca tataaatagt atttattatc ttaatacttc tttcttagaa
    20401 ttccctctct ccaaatcgct tccaaaaagc ctgtcccata tccgatcaat tggacaaaag
    20461 ctgctatgat agataacaac gcaacgattc cgttcttatt tctcactaaa gcgtcaaaaa
    20521 agatcagcga aatataaaat aacaatagcc cccatacctt tggaacgaaa aaagcggaaa
    20581 tacatacccc cagcagacct accacaaata aggccggcag gcaatgtacc catttcaatg
    20641 attccgggta cttctggtac aagataatcc tagcgtaccc cgaatgccat acttgccgga
    20701 aaaactggac gaaatttgtt cttcgcttat gatagaccca agcgcccgga aaataacggc
    20761 atttatagcc tgccgcaaaa atccggatac taaaatctat atcctctcca taacgcatat
    20821 cagagaaacc acccaaggct tcatacacct ctttccgcat tcccatatta aaactccgag
    20881 gatagaatgt atccaaatgt ctccggcttc ctcggatccc tcctgtcgta aagaaagaag
    20941 tcatcgagta attgaccgct ttctgtatag cggaaaaaga agaatgcgcc ctgtcggcac
    21001 caccaaaggc atccacctta taacgcatca aggactcgtg tacttgttcc agatagctgg
    21061 ccggaacgat acaatccgaa tccaagacaa tcacgatctc tccttccgca taacgtaccc
    21121 cttgattgcg agccaagccc gggcctgaat tctctatata gaaatagcga atcctcaagc
    21181 ggtcattata ggcattgact acgggctcac aaggtataga agaaccgtcg tccactacga
    21241 taacctcaaa atgtacatat gtctgccggg taagactgtt taataaatcg tttatttcct
    21301 ccggacgatt gtagacagga ataataattg aaaatacttc cattaagcta gatttaatct
    21361 gccgacaaaa gtaaagagtt aaaaagcgtg tatcaaaaaa gggcactgga caaatagagg
    21421 acatagctgg acatcgaata ccccctattt tttaccccat aatagaaaaa ctggacaaaa
    21481 gacataagat acgttcagtt cattcatgca gaataatcta tttatcaata gcttacaaaa
    21541 tacaatacta tccgctacta tttggacaaa gactggacgc acacaatatt atttcattcg
    21601 cacatctgcc ccccacatta atttttcccg aagcgtctga taaaaagtat ggttatagcg
    21661 cttgatgact ttcgtcgtat aatcggcctt gctcatcttt aattcgatac ctgccgggaa
    21721 tatttccgaa cgtccatcca aagagatcag aaaatattta ttccggctct ctacccgaag
    21781 cgttattata tctgaatccg gaatcaccaa cggacgcacg ttcaaggaat gcggagcgac
    21841 cggactcaag acaatgctat tactttgcgg gacgataatc ggcccattta cgctcatcga
    21901 ataggccgtg gaaccggtag gtgtagccac taccaaacca tccgcctgat aagaagtcag
    21961 atattcccca ttcaagaatg tatgaatcgt aatcatcgag gaactatcac gcttcagcac
    22021 ggcgatctcg ttcaaggcat aattatatcc gcgaaacgca cggtcttccg tatataaacg
    22081 caagagggtt cgttcctcta ccttatagta attcttaaaa atctcatcca gcgtatcctc
    22141 aacctcatta ctgctgacat ccgcaaggaa acccagccgt ccggtattaa tgcctaaaat
    22201 agggatatcc tgtttattta cccgggccgc cgtacgaagg aacgtaccat ctcctcccac
    22261 gctaagggct atatccagat caaactcatc acccactaat agcccgctca ccactggctc
    22321 aaaaccaaaa gcatcggtaa ggaatgtata aaaagggctg tccacataaa tatcagcctc
    22381 ttgttcacga agcttctcaa acaggcgttt aatcagattc tgtctctcga tctgatattc
    22441 acttccaaat attccaactt tcattctacg ctccttactt tacatattca tataatgtaa
    22501 taactcattc atccgctgct gcaacatatc atccaccatc cccttctcca taaaatgata
    22561 aagcaccgta taattgaaac gctcgaaact acggatcacg ggagaggcat cttccaaatc
    22621 aatcttaagg gttataagca gacggcccgt atctttatct tgatgggata gcaaattaag
    22681 gacatgggca ttattcgcct ctaccaaacg ggcgatatcc gttaatgaat aatcctgtgg
    22741 catcatttcc aatacgatca cgcttccagc cgcctccgca ttacatagct cggataaagc
    22801 atctaccaaa cgatcccggg taatcgcccc caaataagtt ccgtccacgg aaaccacagg
    22861 caacaggctc aatccatatc gggttatcat tgccaacgct tcatgtaaat gtccattttc
    22921 cgaaatcgcc ggagcgaata aaaccggctc accgatcgta gccgaaggat ccagcatcgc
    22981 caataagtct ttttccgaca ctaaacactg gtatgcgtta tcactcaata acggaagatg
    23041 cttgagttta aaatcctcca ttaacgccaa cgcatattcc gctgtgtcaa aactttttaa
    23101 caccggaatt tcctttgtta tgaaatcttt caccaacatt attctgttaa ttccctaaat
    23161 cctgctaaat ttgccgatac ttttgtgcaa atgtaatgaa agaaaaaaga tatacgatat
    23221 acaatgacaa atttaagtgt aaacattaac aaggttgcta ctattcgtaa tgcgagaggt
    23281 ggcaatatgc caaacgtgct gaaagtagcg caagactgtg aattattcgg ggcacaagga
    23341 attacggttc atccccgtcc ggatgaacga cacatacgct atagcgatgt ttatggacta
    23401 aaacctctta tccggacaga atttaacata gaaggttatc cttgtgataa attcatcgac
    23461 ttggtattga aggtaaaacc gacccaagtc acactggttc cggacgctcc ggatgccatc
    23521 acgtcgaact caggttggaa cgtaaaggac aatttcgatt acttaagcga attggtagac
    23581 acctttacct cacaaggaat ccgtacatcc atcttcgtcg gaacagactt ggcgaatatc
    23641 gaactagcgg cgaaaacagg tacagaccgt attgagctat atacggaacc ttatgcgacc
    23701 ttttatccgg aagatcgtga caaagcgatc gctccttttg tagaggccgc tcaattagct
    23761 aaaaacttag gattaggcgt aaatgccgga cacgacttga gcttagaaaa tctggctttc
    23821 ttcaacaaga atatcccttg gctggaggag gtttctatcg gccatgcctt gatttgtgat
    23881 gcgctctatc atggtttgca agagacgatc gctttataca aggcatgctt gaataattga
    23941 gaatggagaa gaattgaata ttgaaaatta taacctataa ttcaaaacga tgagtatttt
    24001 actttcacta caggccgtag gctctcaaac ggcagatcaa atgccggatt taacggctgt
    24061 tgccgttccc acagaagcgg aaatcaatgt gatagacctt gcctttaagg gaggttggat
    24121 tatggtggta ttgttactgc tctctctgat ggctatttat atttttgttc aacg
//
LOCUS       DBMDTB010000062        23969 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_733_length_23969_cov_10.967739, whole genome shotgun sequence.
ACCESSION   DBMDTB010000062 DBMDTB010000000
VERSION     DBMDTB010000062.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 23969)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 23969)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23969
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_733_length_23969_cov_10.967739"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..1066)
                     /gene="mutY"
                     /locus_tag="ACZPB4_10845"
     CDS             complement(<1..1066)
                     /gene="mutY"
                     /locus_tag="ACZPB4_10845"
                     /EC_number="3.2.2.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HIR1098743.1"
                     /translation="MLQYESELEISRILVEWYETYKRELPWRETRDPYIIWISEIILQ
                     QTRVVQGLEYFLRFTERFPDVASLAVAEEDEVLKYWQGLGYYSRARNLHAAAKSIMER
                     FNGVFPENYKEVLSLKGIGEYTAAAIVSFAWNQPCPVVDGNVYRVLSRLFAVDTPIDT
                     TKGKKQFAELAGMILDPKNAGTHNQAIMELGALQCVPQNPDCGVCPLKDKCVAFASGN
                     VQAYPVKQNKTKTRDRYFHYLYIIYKEQTWMNRRTGKDIWTGLYEFPLIETDHAMDFS
                     GLCETQAFRNLLGDAGKLSITQGLSNVKHTLSHQILYASFYQIEIEQVPESLGNYLSL
                     PCRDIEKYAVPRLIHIYLEKL"
     gene            1256..1528
                     /locus_tag="ACZPB4_10850"
     CDS             1256..1528
                     /locus_tag="ACZPB4_10850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HIR1098744.1"
                     /translation="MTKADIVSEISKSTGIDKQTVLASVESFMDIVKSSLAQGENVYL
                     RGFGSFVIKKRAQKTARNISKNTTIIIPEHNIPSFKPAKTFIGEVK"
     gene            1753..3330
                     /locus_tag="ACZPB4_10855"
     CDS             1753..3330
                     /locus_tag="ACZPB4_10855"
                     /EC_number="3.1.26.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA];
                     GO_process: GO:0006397 - mRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rne/Rng family ribonuclease"
                     /protein_id="HIR1098745.1"
                     /translation="MISELVVDVQPKEVSIAVLEDKSLVELQKEARNVSFAVGDIYLG
                     KVKKLMPGLNAAFIDVGYKKDAFLHYLDLGPNFNTQQKYLKQLLSDPKKAPVLSKTQI
                     LPEIEKNGSISDVLKVGQEVLVQIAKEPISTKGPRLTSELSFAGRYIVLIPFADKVSV
                     STKIKSSEERARLRQLIQSIKPKNFSVIVRTSSEGKRVAELDHELKTLMKRWEDNIVK
                     VPKLKAPAIIYEETARTVALLRDIFNPSFQNIYVNDKEVYNNVRDYVSLIAPGREEIV
                     QLYTGELPIFDNFAVTKQIKSLFGRTVTYKSGAYLIIEHTEAMHVIDVNSGNRSKGSD
                     AQEKTAIDVNIAAADEIARQLRLRDMGGIIVIDFIDMAEAANRQKLFEHMTKAMANDR
                     AKHNILPLSKFGLMQITRQRVRPAMDVDTSEDCPSCFGTGTVKPSILFTDSLEEKIDC
                     LVNKHHVKKFTLHVHPYVAAYVNKGLFPLSMKWKMKYTHGLKVIPNQSLAFLEYKFFD
                     ADKNELDMKEEKEIINK"
     gene            3532..5463
                     /gene="dnaK"
                     /locus_tag="ACZPB4_10860"
     CDS             3532..5463
                     /gene="dnaK"
                     /locus_tag="ACZPB4_10860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012457876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HIR1098746.1"
                     /translation="MGKIIGIDLGTTNSCVAVLEGNEPVVIANSEGKRTTPSIVAFVE
                     GGERKVGDPAKRQAITNPEKTIFSIKRFMGETYDQVQKEINRVPYKVVRGDNNTPRVD
                     IEGRLYTPQEISAMILQKMKKTAEDYLGQEVTEAVITVPAYFSDAQRQATKEAGEIAG
                     LTVRRIVNEPTAASLAYGLDKTNKDMKIAVFDLGGGTFDISILELGDGVFEVKSTNGD
                     THLGGDDFDHVIIDWLAEEFEREEGVDLRKDPMALQRLKEAAEKAKIELSSTTSTEIN
                     LPYIMPVNGIPKHLVKTLTRAKFEQLADGLIQACIEPCRQSLKDAGLSTSDIDEVILV
                     GGSTRIPAVQAIVEKFFGKAPSKGVNPDEVVAVGAAIQGGVLTGEVKDVLLLDVTPLS
                     LGIETMGGVMTKLIESNTTIPTKKSETFTTAVDNQPSVEIHILQGERSLAKDNKSIGR
                     FHLDGIPAAQRGVPQIEVTFDIDANGILNVSAKDKGTGKVQSIRIEASSGLSDDEVKR
                     MKEEAAANAEADKKEKERIDKLNQADSMIFQTEKQLKDLGDKLPADKKAPIEGALNKL
                     KEAHKAQDIAGIDAAMAELNSVFQAASQEMYNAQGGGAQGGPQADPNFGGQQAGGNAG
                     SSNNSKDGNVTDVDFEEVK"
     gene            5671..7587
                     /locus_tag="ACZPB4_10865"
     CDS             5671..7587
                     /locus_tag="ACZPB4_10865"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1098747.1"
                     /translation="MLARSIQKYYIFVLLFLLAILQSSCQQSGNKYRILVVHSYESDY
                     VAYKDCDRLIRKSLEKKGINPSIQTFYLNCEQYAAPAEEKRMYLYLDSISTWKPDLIL
                     VYEDQATYTLMQCHHPLISTIPIVFGGVNFPNKALLAQYSNVSGFWDEPDYVTNIRLI
                     EHLLGKSTIYMLHDSTYIDRHIKATLHEQCAQVDIRVDNNRIMYIPVEIATLERVNQS
                     LKRPDSTTVNIVPVQGDKLSAVSWYMSKHVPYIYYLQAKRDYRVLNTSRFSSKPSFTA
                     INEDLGYSNKLVGGYITSLETQIEESTDRAAEILKGSTSESFPQITKSKKNYVFDFNE
                     VKYWNIDKRLLPKDAILLNFPFKDQYPRLFWSLIILVSTMCCFVFGSFIIMYTQESKA
                     KRQAQKALLHEKESLAEALEKANESDRMKSVFLANMSHEIRTPLNAIIGFSSLIAELD
                     LTAEEKEQYANIITTNNELLLKLVNDILDLARIESGGIVFHKESCNLTDLVKTLYKQH
                     LSDVPEGIEFKEKCPDTPICLYSDKERLYQALENILKNAIKFTSAGFIEIGYEYPADA
                     QDVRLYVQDTGIGISPEDQEAIFERFKKLDDFVQGTGLGLSICQAIVKQLNGRILLKS
                     EKNKGCRISLVFEL"
     gene            7681..9987
                     /locus_tag="ACZPB4_10870"
     CDS             7681..9987
                     /locus_tag="ACZPB4_10870"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1098748.1"
                     /translation="MANTSYRYLFLLLLPLFLLVANSCERSTTEKRILIVQSYEPDFQ
                     AYKDVEETFKNGFQKEGIHASIFTFYLNCEAYQSPEEKQRIYTELNTLSLWKPDIIIV
                     NDDQATYSLLACEHPLLDSVPIVFTGVNYPNIPLIQKYPNVSGFWDKPDYRKNVELIE
                     RIMGKCVIVRVSDSTALDKKILKDMDEQIKGLCSKARPDYLKYPQYSSPSDKKRSSSL
                     VRFPKVPFDSLYIQTIQPRTSSNLIWGLGTSTYNKAYLATKRDYTSIALGRFCSFPSF
                     SAINESVGYDGDFIGGYMTPVESQTQEALRRAASILKGTPANSFPQITESAKNYLFDY
                     PTLNKWGIDWKELPQNSIFLNMPFVVRYQTYIILCGILLTLFILWTLFYQRVQYRREA
                     SHKKQAQESLRKEKEFLSLALESGDIFAFRYSNGVFEFDHDFYKSLDMLIKPITSTQF
                     QESIHPEDREDFIQHKHLLDTGFPSRKITRRRYNFNGKGHIWWEFRYAQAKNGQDSTR
                     NNVGVNGLCLNIQQSKEVEEDLIKARIRAEEADQMKSAFLANMSHEIRTPLNAIVGFS
                     ELLTSDMEISPNERDEFMQVISKNSDLLLKLINDILDLSRIESGKMSFTLTNCDLNEL
                     LSHIYRTHQLLMPQGVALKIQLPVLPAIIQADLHRLTQVITNLINNAAKFTTQGYILI
                     KYDYTQDKRWIQISVTDTGKGIPADKQAQVFERFNKLDEFAQGTGLGLAICQIIIEHF
                     GGYITLESKEGEGSTFIVTLPYTPGLSV"
     gene            complement(9990..11240)
                     /locus_tag="ACZPB4_10875"
     CDS             complement(9990..11240)
                     /locus_tag="ACZPB4_10875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HIR1098749.1"
                     /translation="MEKRSPWAWIPSLYFAEGLPYVVVMTLSVIMYKRLGVSNTDIAL
                     FTSWLYFPWVIKPIWSPFVDLIKTKRWWIYGMQLLIGGGMAGVAFVLPGDFFLRFTLA
                     FFWLMAFSSATHDIAADGFYMLGLTEEQQAFFIGIRNTFYRVAMLTGQGLLVMLAGLL
                     EESTGRISFAWSLVFFVLAGTFIALALWHKYILPRPASDAQRTNITPHTILVEFGNTF
                     VSFFNKKGIVPALLFMLTYRLGESQLVKLASPFLLDGREVGGLALSTGEVGFAYGTVG
                     VISLLLGGVLGGLAISRSGLKTWLWPMALAISLPNLVYLYMAYTMPESIVVVNACVAV
                     EQFGYGFGFTAYTMYLMLFAEGEYKTSHYAISTGFMALGMMLPGMASGWIQEQIGYQH
                     FFIWVMICCIPLFIVLPFLRFKKK"
     gene            complement(11261..12046)
                     /locus_tag="ACZPB4_10880"
     CDS             complement(11261..12046)
                     /locus_tag="ACZPB4_10880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HIR1098750.1"
                     /translation="MTEDLRISMIQSHIIWEDREENLGYYGELLRRVSGRTDLAVLPE
                     TFTTGFSMDVEKQADTMEGQTVPTIKEWAKKYKLAVAGSFIAKDNGKFYNRAFFITPE
                     GEEYYYDKRHLFRMAEEDKHFSAGDKRLIVPYKGWNICLQVCYDLRFPVWSRNVNNEY
                     DLLIYVANWPEARKKAWKALLHARAIENMAYVCGVNRVGVDGKGFLFRGDSMIYNAKG
                     KKLADAGKREEITRTCTLKKSELDEFRAKFPAWKDADGFSIDF"
     gene            complement(12204..12752)
                     /locus_tag="ACZPB4_10885"
     CDS             complement(12204..12752)
                     /locus_tag="ACZPB4_10885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HIR1098751.1"
                     /translation="MKKAISKAILRMAGWKLGPVDGVDLPKCIVCVAPHTSNWDFIVG
                     KLFYTSIGCNAGFLIKKEWFFFPFNLLFNWLGGVPVDRGKRTSVTDQMVERFKTSERF
                     QLAVTPEGTRKRAKDWKKGFYFIALKANVPIVVAYFDYGKKEVGTKGVFYPTGDVDKD
                     IHTIREMYRGVTACHPENFVQV"
     gene            complement(12755..13045)
                     /locus_tag="ACZPB4_10890"
     CDS             complement(12755..13045)
                     /locus_tag="ACZPB4_10890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098752.1"
                     /translation="MAKRRILKKEISYVAGELFTEALVCKLYIPGVNQEKADALMARI
                     LDMQDSYIVRAGHPDGKDNKALVRNYYRKLREDLQNEVNAIADEIGELSKDK"
     gene            13174..14832
                     /locus_tag="ACZPB4_10895"
     CDS             13174..14832
                     /locus_tag="ACZPB4_10895"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HIR1098753.1"
                     /translation="MNEMIKTPEFLFESSWEVCNKVGGIYTVLSTKAHTLQQIFNDKV
                     IFIGPDVWANTTAPDFTEDASLFEDWRKHAEAVDHLKVKVGRWNVPGTPPVILVDFKS
                     YFSERDAFFYSMWENFRVDSIHAYGDYDESCIFAYAVGKVIESFYHFYKLENKKVAAL
                     FNEWMLAMGALYIQKQIPAIATLFTTHATSIGRSIAGNNKALYAYMDGYNGDQMAKKL
                     NMEAKHSVEKQAAHYVDCFTTVSDITARECKQLLDKAPDIVTPNGFEPNFVPEGKEYA
                     KKRKEARRTLINVAEKLLGCSIDPNALLVSTSGRYEYRNKGIDVFIEAMNRVRTSGRL
                     QREVVAFIMVPAWVRAARADLKEAIEQDIKTTSPLQIPFITHWLHNMPEDKVLNYINH
                     AGFTNAASEKLKIIFVPCYLDGKGGIFNKAYYDMLIGMDATVYPSYYEPWGYTPLESI
                     AFGIPTITTNLAGFGMWAKKTVSGDNLSEGVEVINRTDFNYFEVADAIMNSILALSQK
                     DATDIEEIKQRCFDLARKAEWSKFIDYYLTAFDIAIKHAEERNS"
     gene            14906..17476
                     /gene="glgP"
                     /locus_tag="ACZPB4_10900"
     CDS             14906..17476
                     /gene="glgP"
                     /locus_tag="ACZPB4_10900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004645 - 1,4-alpha-oligoglucan
                     phosphorylase activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucan family phosphorylase"
                     /protein_id="HIR1098754.1"
                     /translation="MKIKANNANSPIWKDVYSHSKLPQQLEPLNEIATNLWWVWNHEG
                     AKLFGKIDKQLWKSTEGNPVQLLQSLSHKRMEEILADKELMAEIQKVYADFKAYINVK
                     PDKTQPSVAYFSMEYGLTNVLKIYSGGLGVLAGDYLKEASDSNIDLCAVGFLYRYGYF
                     TQTLSMDGQQIANYEPQNFNALPLTQVLQSNGEPMVLEVPYPGRTVYVHIWKVSVGRV
                     PLYLMDTDIPQNSEWDRSITHQLYGGDWENRMKQEYLLGIGGIMMLNKLGIKKQIYHC
                     NEGHAALINAQRLVDYIQNDGLSFNQALEVVRASALYTVHTPVPAGHDYFDEGLFGRY
                     MGEFPGKLGISWQDFIDMGRENPGSNEKFSMSVFALNTCQEANGVSWLHGKVSQRMFA
                     PVWKGYFPDELHVGYVTNGVHMPTWAATEVKKFYADKLGTKLFEDQSNRKCWEGIQNV
                     SDEEIWNLRMTLKNKLIDYIRVQYKDSWLKNQGDPSKVVSILEKINPNALLIGFGRRF
                     ATYKRAHLLFTDLDRLAKIVNNEKFPIQFVFTGKAHPADGGGQGLIKHIVEISRRPEF
                     LGKIIFLENYDMRLARRLISGVDVWLNTPTRPLEASGTSGEKAEMNGVLNFSVLDGWW
                     YEGYVEGAGWALTDKRTYENQQYQDQLDAATIYHCLETEIIPTYYAKNSKGYSPDWIQ
                     YIKNSIAKIAPDYTMKRMLDDYEDRFYHKLATRSAHISANNYEIAKQLAAWKEEVAQH
                     WDSFQVESFTCDQDLTVNGPVVGKEYNFNLVIDRHELQGMLGAEMVVMKEDPEKHTLS
                     PINTAQFELMKEEGSKLFFKLTTTPSEAGNHKIGFRVYPVNKELPHRMDFAYVRWIQL
                     "
     gene            complement(17693..19075)
                     /locus_tag="ACZPB4_10905"
     CDS             complement(17693..19075)
                     /locus_tag="ACZPB4_10905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OmpP1/FadL family transporter"
                     /protein_id="HIR1098755.1"
                     /translation="MKKKVVLGAALMMMPLVSFAGGYLTNTNQHAAFLRSLSRGAAID
                     IDGALSNPAGLSFLPTDGFRVGVSIQSAFQTRDIDASFSTYNGFDPVNKVPTVSDVPY
                     KKYYKGKAAAPVIPSVFAAYKKGDWTISGFFAITGGGGKASFDDGLPMFESAAMAGIF
                     QESVAKYIKTGGQSPIVTPDMYTINSAMDGKQYIYSLQLGLSYKITDWLSAFAGGRMN
                     YFSGNYDGYLDAKLKQNFGGADLMNLALDCDQTGWGLTPVLGVDVKYGKFNFGAKYEF
                     KTNLNIENNTKKLDYPDSAEGLVGPYKHGVNTPNDIPSMLSVAASYRFLPMLKASVEY
                     HFFDDKKAGMAGGKQKELERGTNEYLFGIEWDVVKRLTISGGAQITDYGLSDNFQSDV
                     SFSCDSYSLGFGAKVMLSEKMALNVGYMWTTYHDYTKKMDNYCGTGLPGQNVYSRTNK
                     VFGLSLDYAF"
     gene            19423..20592
                     /locus_tag="ACZPB4_10910"
     CDS             19423..20592
                     /locus_tag="ACZPB4_10910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HIR1098756.1"
                     /translation="MKRLALLAALLLPLSMAFAQQNVGFKTDKVEPLVINSDNSVTFY
                     VEAPKAKSVSVKGDWEASEGNGQMTKGKNGTWSYTTPPLPSEMYTYRLNIDGIYNIAP
                     NNPFSCRDVGTLFSLFYINGGNGDYYQVRDVPHGNVTTTWYHSDILGSERRLSVYTPP
                     FYDKNIQSYPVLYLLHGSGGDENAWLELGRTARIMDNLIAEGKIQPMLVVMPNGNPSK
                     QAAPGETPDNLNYKPAMSNSFPGYKDGSYEKSFTEIIHFIDNRYRTIPDKRHRAIAGL
                     SMGGFHTLYISLNYPDYFNYIGLFSAGLSANGVDPNSPMYTNLDEKLGNLKRSGYQLF
                     WIGIGKDDFLYDANQQFRQRMDSLGMKYQYVESTRGHIWANWRAYLLQFAPMLFK"
     gene            20606..21484
                     /locus_tag="ACZPB4_10915"
     CDS             20606..21484
                     /locus_tag="ACZPB4_10915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HIR1098757.1"
                     /translation="MNLNIPQYDFYKHKYGDELLIDVVPLNTIKKYLKEQPVHILTYY
                     DITLITSGEGEFLIDHQANRVKPQDIIFTRPGEIRKWDDKTIQDGFALIFEEEFLLSF
                     FNDPAFLRNLSYFHTERRSSKLSLDKKAYGRISELISEIDKEIKDYQSKDKHLLRALL
                     YETLMLLNRLYASSNALPPDTNARSKSIYVDRFIELVNHSFKQDHSIRSYADRLCITP
                     NYLNEIVKNATGISAKQYILNKILIESKRLLTYTDLPISAITEALGYEDPSYFIRLFR
                     SQTNMTPLNYRRNTKP"
     gene            21568..22032
                     /locus_tag="ACZPB4_10920"
     CDS             21568..22032
                     /locus_tag="ACZPB4_10920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YybH family protein"
                     /protein_id="HIR1098758.1"
                     /translation="MRQYKSWIAALILGSTLSTNAQQKNMENKTLNENIPEMIISLEK
                     EALASTDPMAFVELSDTDVIYFDPSLETKIEGLEQLRTYYKGMQLPPADHFDMIRPIV
                     QVTQNIAVLTFNLDSYLSDKVIKWNCTEVYRRNPDNQWKIIQTHWSYVKPID"
     gene            22076..23065
                     /locus_tag="ACZPB4_10925"
     CDS             22076..23065
                     /locus_tag="ACZPB4_10925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrillin family protein"
                     /protein_id="HIR1098759.1"
                     /translation="MYYIDYSLNTNYMIRNLLKAANALTFSTMFLLLLAGCNKNTIIF
                     EDGTSPNGSSGNEDPGNSTLVTFNASVEGRNLLRSMSPMNKGIQSRVYVFDSSAGTKG
                     SPEASGLYITSSPGVLTGSDGYKMFLSNGTYNFYAVSDNFSTIPPTFTSGVSEPLFNG
                     IDYLWWNAIQQDVNSSQINIPIVYGHVATQVVVELTGGEGITINQLVSAMITPPETGA
                     TMDLGTGIITPATAFGKADKMGINGLTAQYIMLPIRHTAPMTLTLEISADNENSTRTY
                     TTQVPLPDGELKAGNSYLFKAVINGNSVTLASVNVKDWTDVDETGKPLYPTQN"
     gene            23153..>23969
                     /locus_tag="ACZPB4_10930"
     CDS             23153..>23969
                     /locus_tag="ACZPB4_10930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003906 - DNA-(apurinic or apyrimidinic
                     site) endonuclease activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase family
                     protein"
                     /protein_id="HIR1098760.1"
                     /translation="MIEIPESATIGKQASETLKGKRIAHVIESNSPHRFTFYNGDPAE
                     YSNRLVGRTVLGAQGYGAFVDILMDADTHLLIGDGTNMRYYTSAEKAPKKYQLMIVFE
                     DDSFLAFTVSMYGSIYAFKGEFDNPYYQGSIHKLCPLDERFDKAYFISLIRNLKKDIS
                     AKALLATEQRIPGLGNGVCQDILFNARISPKRKISTLSEEDIDSLFNTVKSTLEEMTC
                     RGGRDTEKDLYGALGNYRTILSKNTYHDPCPVCGERIQKEAYLGGSIYYCPHCQ"
BASE COUNT         7206 a         5647 c         5069 g         6047 t
ORIGIN      
        1 ttaatttctc taaataaata tgtatcagcc ggggaacggc atacttctca atatcccgac
       61 aaggcagaga gaggtaattc cccaaggatt ccggaacctg ctctatctct atttgataga
      121 aagaagcgta taaaatttga tgggagagcg tatgctttac attcgataac ccttgggtga
      181 tactcaattt tccagcatct cccaataggt tacggaaggc ttgcgtctca cacaaaccgg
      241 aaaaatccat cgcatgatcc gtctcgatca atggaaattc atacaaaccg gtccagatat
      301 ccttccccgt ccgtctgttc atccaagttt gttctttata tataatgtat agatagtgga
      361 aataacgatc ccttgtcttc gtcttatttt gtttcaccgg ataagcttgc acattgccgg
      421 aagcgaacgc cacgcattta tcttttagcg ggcacacccc gcagtccggg ttttgaggaa
      481 cacattgcaa agcacccaat tccatgatcg cctgattatg cgtccctgcg ttcttagggt
      541 ccaagatcat tccggccagt tccgcaaatt gctttttacc cttcgtggtg tcgatcggcg
      601 tatctacggc aaacaaacgg gaaagtaccc ggtacacatt tccatccacg accggacacg
      661 gttggttcca agcaaaggag acgatcgccg ccgccgtata ctccccgata cctttcaagg
      721 ataatacctc tttataattc tccgggaaaa ccccgttaaa ccgctccatg atagatttag
      781 ccgccgcatg taagttacga gcccggctat aataccccaa gccctgccaa tatttcagca
      841 cctcatcctc ttccgccacc gctagagatg ccacatccgg gaaacgttcg gtaaaacgca
      901 aaaaatactc caatccctgt acaacccggg tttgttgcaa tataatctcc gatatccaga
      961 tgatataagg gtctctcgtt tccctccaag gaagctctct tttataggtt tcataccact
     1021 caaccaatat ccggctgatt tctaactcac tttcatactg taacataact gctccctttc
     1081 tctcttttca acatcataac tatttgatta ccgcaaacat acatatatat tacgaatcga
     1141 gaagaatctt tttatttaaa aattgaagct caattctttt tccacttaaa taaaaagcta
     1201 tatatttgca ttccaaaaaa ttaataggtc aaaatcaatt aattaattta tagacatgac
     1261 taaagcagat attgttagcg agatttcaaa aagcactggt atcgacaaac agacagtgct
     1321 agcaagcgtt gagtccttca tggatatcgt aaaaagttct ttagcccaag gcgaaaacgt
     1381 ttacttgaga ggtttcggaa gtttcgttat taagaagaga gctcaaaaga cagctcgtaa
     1441 tatttcaaaa aatactacga tcatcatccc ggaacacaac attccgtcat tcaagccggc
     1501 taagactttt attggtgaag ttaagtaatt aattattata cgtttaattt aaaattttaa
     1561 agcgatgcct agcggaaaga aaagaaaaag acataaaatg tctacgcaca agcgcaaaaa
     1621 gagactgaag aagaatagac ataagaagaa ataagtctat ctaacgaact ctaaagaaca
     1681 aacttaataa gtgacctttt aagtttgttc tttgcgtatt ttataaggtc tgatcttaaa
     1741 aacacatctt aagtgattag tgaattagta gttgatgtac agcccaaaga ggtatctatc
     1801 gccgtcttgg aggacaagag ccttgtggag ctccaaaagg aggcccgcaa cgtctcgttc
     1861 gctgttggtg atatctatct aggtaaggtt aagaaactga tgccgggctt aaacgctgcg
     1921 ttcattgatg tcggttacaa aaaggatgcg tttcttcact atttggactt aggtcctaac
     1981 ttcaacaccc aacagaaata tttaaagcaa ttgctgagcg atcccaaaaa ggcgccggta
     2041 ctgtcgaaaa ctcagattct accggagatc gaaaagaacg ggagtattag cgacgtgctg
     2101 aaagtaggac aagaggtgtt ggttcaaatt gctaaagagc ctatctcgac gaaaggtccc
     2161 cgattgactt ccgagctttc ttttgccgga agatatatcg tgctgatacc gttcgccgat
     2221 aaagtatctg tctccaccaa aattaaatca agcgaggaac gagcccgttt gcgccagtta
     2281 atccaaagta tcaaaccgaa gaatttcagt gttatcgtac ggacatcctc ggagggcaag
     2341 cgtgtcgcag agcttgatca tgaattgaag acattgatga aacgatggga agataatatc
     2401 gtgaaggtgc ctaaactcaa agctccggct attatttatg aggaaacggc acgtaccgta
     2461 gctttgcttc gggatatatt caacccctct ttccaaaata tttatgtaaa tgacaaggag
     2521 gtctataata atgtccgcga ctatgtaagc ttgatcgcac cgggacggga agaaatcgta
     2581 cagttatata cgggagagct tcctatcttc gacaactttg cggtcaccaa gcaaatcaag
     2641 tcgctattcg gacgaactgt cacttacaag agtggagctt acttgattat cgagcacacg
     2701 gaagctatgc acgttatcga cgtgaacagc gggaaccgtt ccaaaggcag cgatgcccaa
     2761 gagaagacag ctatcgacgt aaatatagcc gccgccgatg agatcgcccg tcagctccgc
     2821 ttacgagaca tgggaggtat catcgtcata gactttatcg atatggcaga ggctgccaac
     2881 cggcaaaagc tatttgaaca catgacaaag gcaatggcaa atgaccgggc taaacacaat
     2941 atccttcctc ttagtaagtt tggcttgatg cagattaccc gtcagcgggt acgtccggca
     3001 atggacgtgg atacgtcaga agactgccca tcctgtttcg gaacaggaac ggttaagcct
     3061 tccatcctgt ttaccgacag cctggaagaa aaaatagatt gcttagtaaa caaacatcac
     3121 gtgaagaaat tcaccctgca tgtacatccg tatgtcgcag cgtatgtgaa caaggggttg
     3181 ttccccttga gcatgaagtg gaaaatgaag tacacacatg gtttaaaagt tattcccaat
     3241 caaagtctcg cctttcttga atacaaattc tttgatgccg acaagaatga gcttgacatg
     3301 aaagaagaaa aggaaataat caacaaataa caagagaagc cccgggccta ttaaaacggt
     3361 tccggggctt tctgtattct gccaaaccgc caaaatgtca cgattcatga cacgtattat
     3421 ttattttcaa acccaaactt ctttggcacg gcatttgttg aatactatgt gaatccttta
     3481 aacaaggagg atgacggacg atgaataata acaattaaaa tatttacaat catgggaaag
     3541 attattggaa tcgacttagg aacaaccaac tcttgtgttg ccgtattgga aggtaacgaa
     3601 ccggttgtta tcgcgaacag cgaaggtaaa agaacaacac cttcaatcgt agctttcgta
     3661 gaaggcggcg agcgtaaggt aggtgatccc gcaaaacgtc aggctatcac caatcctgaa
     3721 aagactatat tctctatcaa acgtttcatg ggtgaaactt atgaccaagt acaaaaggaa
     3781 atcaatcgcg ttccttataa agtagtgcgt ggtgataaca acactcctcg tgtagatatc
     3841 gaaggacgtt tgtatactcc gcaggaaatc tcagcgatga tcctgcagaa aatgaaaaag
     3901 acagctgagg attatttggg acaggaagta acggaagccg ttatcacagt acctgcttac
     3961 tttagtgacg ctcaacgtca ggctacgaaa gaggctggtg agatcgcagg tttaaccgta
     4021 cgccgtatcg taaacgaacc gactgccgct tctttagctt atggtttgga taagacgaac
     4081 aaagacatga agatcgccgt attcgactta ggtggtggta cattcgatat ctccatcctt
     4141 gagttaggtg acggcgtatt cgaggtaaaa tcaacaaacg gtgatactca cctaggtggt
     4201 gatgacttcg accacgtaat catcgactgg ttggctgaag aattcgaacg agaggaaggc
     4261 gtagacttac gtaaagaccc gatggcttta caacgtttaa aagaagctgc cgagaaagcg
     4321 aagatcgagt tgtcaagtac gactagcacg gagatcaact tgccgtatat catgccggta
     4381 aacggtattc caaagcactt ggttaagact ttgactcgtg ctaaattcga acaattggct
     4441 gacggtctga tccaagcatg tatcgaaccg tgccgtcaat ccttgaaaga cgcaggttta
     4501 tcaacttctg atatcgacga agtgatcttg gtaggtggtt ctactcgtat cccggctgta
     4561 caggctatcg ttgagaaatt cttcggtaaa gctccatcta agggcgttaa cccggatgaa
     4621 gtagtagccg taggtgcagc gatccaaggt ggtgtattga caggtgaggt taaggacgta
     4681 ttgttgttgg atgttactcc gctgtcttta ggtattgaga caatgggtgg tgtaatgact
     4741 aaattgatcg agtctaacac gaccatcccg accaagaagt ccgagacatt tacgactgct
     4801 gtagacaacc agccttctgt tgagatccac atcttgcaag gagagcgttc tttggctaaa
     4861 gacaacaagt ctatcggccg tttccaccta gatggaatac ctgccgcaca acgtggtgtc
     4921 cctcagatcg aggttacatt cgatatcgac gccaacggta tcttgaacgt atccgccaag
     4981 gataaaggaa ccggtaaagt acaaagtatc cgtatcgagg cttccagcgg tttgagcgat
     5041 gatgaggtta agcgtatgaa agaagaggct gccgcaaacg cagaggccga taagaaagag
     5101 aaagagcgta tcgataaatt gaatcaagcg gatagcatga tcttccagac cgagaaacaa
     5161 ttgaaagatc ttggcgacaa gcttccggca gacaagaaag ctccgatcga aggtgccttg
     5221 aacaaattga aagaagctca taaggctcag gatatcgcag gtatcgatgc tgctatggca
     5281 gaattgaaca gtgtattcca agcagctagc caagaaatgt acaacgctca aggtggcggc
     5341 gctcaaggcg gtccgcaagc agatcctaac ttcggtggtc aacaagctgg cggtaatgca
     5401 ggtagcagca acaacagcaa agacggtaac gttacggacg ttgactttga ggaagtaaaa
     5461 taaaaagaag cggttttaat cgctccttta ctccacataa gatagaaaaa cggctatcgg
     5521 gtccttcggg atctgatagc cgttttttat tttagcccta tatattcaat aaaaaagcca
     5581 ttgatatcca ataattatta ataagtttgc actcgcataa aaacactcat tttaaattac
     5641 gattaagggc aacgtactaa ttttcgactt atgctagcga gatctataca gaaatattac
     5701 atatttgttc tactttttct gctagccatt ctacagtcct cttgtcaaca gtcgggaaat
     5761 aaatatcgta tattagtagt ccattcctat gaaagcgact atgtagctta taaagactgc
     5821 gatcggttga tccggaaatc cctcgagaaa aaggggatta atccgtcgat ccaaacattc
     5881 tatttgaact gcgagcaata tgcggcacct gccgaagaaa aacggatgta cctgtatcta
     5941 gattcgatct ccacttggaa acccgatctg atattggttt acgaggatca agcgacttac
     6001 acgttaatgc aatgccatca tccgctaatt tctacaattc ccattgtatt tggcggcgta
     6061 aatttcccca ataaggcact attggcgcaa tattcgaatg tttccggatt ctgggacgag
     6121 cccgactacg tcacgaacat ccgcttgata gaacatctgt tgggcaagtc tacaatttat
     6181 atgttgcacg atagtacgta tatagatagg cacattaagg ctacgttaca tgagcaatgt
     6241 gctcaagtag acattcgggt cgataataat cgtatcatgt atataccggt agagatcgct
     6301 actttggaaa gggtcaatca aagcttaaag cggccggata gtacgaccgt caacatcgtg
     6361 cccgtacaag gagacaagct atcagctgtt tcttggtaca tgagtaaaca cgtcccttac
     6421 atctactatc tacaggccaa acgggattac cgggtattga acaccagccg tttttccagt
     6481 aaaccctctt ttacggcgat caacgaggat ctaggatatt cgaataaact tgtaggtggc
     6541 tatatcacct ccttggaaac ccaaatagaa gaatctaccg atagagccgc ggaaatatta
     6601 aaaggctcca ctagcgaatc attcccacag ataacaaaga gcaagaagaa ttatgtattt
     6661 gatttcaatg aagtcaaata ttggaatatc gataaaaggc ttcttccgaa ggatgctata
     6721 cttttgaact ttccatttaa ggaccaatat ccaagattat tctggagctt gataatccta
     6781 gtcagcacga tgtgctgctt tgtcttcggt agcttcatca tcatgtatac ccaagaatcc
     6841 aaggcaaaac gacaagcgca aaaagcccta ttacatgaaa aggaatcatt agcggaagcc
     6901 ttggagaaag ccaatgagtc cgaccggatg aaatccgtat tcttggctaa catgagtcat
     6961 gagatacgta ccccgctaaa tgcgatcatc ggcttttcaa gcctaatcgc cgaactggat
     7021 ctgacggcgg aagagaagga gcaatacgct aatatcatca cgaccaataa cgagttatta
     7081 ctaaagttag tcaatgacat attggatttg gcaaggattg aatccggagg tatcgtcttt
     7141 cataaagaat cctgcaattt aacggattta gtgaaaaccc tttataaaca acatctttcc
     7201 gatgtccccg aaggtatcga attcaaggag aaatgccccg atacgccgat ctgcttatat
     7261 tcggataagg agcgacttta ccaagcgctc gagaacatac tgaaaaatgc cataaaattt
     7321 acttccgcag gctttataga gatcggttac gagtatcccg ctgacgcaca agacgtccga
     7381 ctttatgtgc aggatacagg catcgggatc tctcccgagg accaagaagc gatattcgag
     7441 cgtttcaaga agctggatga tttcgtgcaa ggaacaggtc ttggattatc gatctgccaa
     7501 gctatcgtaa aacaattaaa cgggcgtatc ttgctcaagt ccgaaaagaa taaggggtgc
     7561 cgcatctcct tggttttcga attataaacc aacctcagaa gccaagaaaa atagacattt
     7621 gtctctttga tatccaatta ctttttatac atttgcactt attatattga agctatacac
     7681 atggcgaaca cttcttatcg ttatcttttt ttattgttgc ttccattgtt tttattggtc
     7741 gcaaattctt gcgaacgctc aaccacggaa aaacgcatct tgatagtaca atcttatgag
     7801 ccggactttc aagcctataa agatgtagaa gagactttta aaaatggatt ccaaaaggaa
     7861 ggcattcatg ccagtatctt cacgttctat cttaattgcg aagcttatca atcgccagaa
     7921 gagaaacaaa gaatatatac ggaactcaat acgttatctt tatggaagcc tgatatcata
     7981 atcgtaaacg atgatcaagc gacctattcc ttattggctt gcgaacatcc tttattagat
     8041 agcgtaccta tcgtttttac cggagtcaac taccctaaca tacccttaat tcaaaagtat
     8101 cctaacgtat ccggattttg ggataagccg gactatcgga aaaacgtcga acttattgag
     8161 cgaatcatgg gaaaatgcgt gattgtacgt gtctctgata gtacagctct tgacaaaaag
     8221 atcctgaaag atatggatga gcaaataaaa gggctatgct ccaaggctag acccgattac
     8281 cttaaatatc cccagtattc atccccatcc gataaaaaga gatcctcttc tttagtgcgg
     8341 ttcccaaaag taccgttcga ttccctctat atacaaacca ttcaaccccg taccagttcc
     8401 aacttgatct gggggttagg tacaagtact tacaacaagg cctaccttgc taccaaaaga
     8461 gattatacct cgatagcctt aggtaggttc tgctcatttc ccagcttctc ggcgatcaac
     8521 gaatccgtag gatatgacgg agacttcata gggggatata tgaccccggt agagagtcaa
     8581 acccaagaag ccttacgacg agctgccagc atactcaaag gcacaccggc caatagcttc
     8641 ccacaaataa cggaaagcgc caaaaactat ctgttcgatt acccgacttt aaataaatgg
     8701 gggatcgatt ggaaagaact gcctcaaaac agcatcttct tgaacatgcc ctttgtggtt
     8761 cgttatcaaa catatattat tctatgcggg attcttctaa ccctatttat cctatggacg
     8821 cttttctatc aaagagtaca ataccgtcgc gaagcctctc acaagaaaca ggctcaagaa
     8881 agtttacgga aagagaaaga attcctctcg ttggctttag agagcggtga tattttcgca
     8941 ttccgataca gcaacggcgt attcgagttc gaccatgatt tctataagtc gttggatatg
     9001 ctgataaagc cgatcacctc cacgcaattc caagagtcta tccaccctga agaccgggaa
     9061 gatttcatcc aacataagca cctgcttgat acaggattcc cttcccgtaa gatcacccgc
     9121 cgccgatata atttcaacgg caaagggcat atatggtggg aattcagata tgcgcaagcg
     9181 aagaatggac aagactccac ccgcaataat gtcggagtaa acgggctctg cttaaatatc
     9241 caacaaagta aggaagtaga ggaagatctt atcaaagccc gtataagggc cgaggaagcg
     9301 gaccaaatga aatcagcgtt cctcgccaat atgagccatg agatacgtac cccgcttaac
     9361 gccatcgttg gattttcgga actgctaaca agcgatatgg aaataagccc gaacgagagg
     9421 gatgagttca tgcaagttat cagtaagaac agcgacctct tattgaaatt gatcaatgac
     9481 attctcgatc tatcccgcat cgagtccggt aagatgtcgt ttaccctcac gaattgtgac
     9541 ttaaacgaat tactatccca tatctaccgc acccatcaat tgttgatgcc ccaaggcgta
     9601 gcgcttaaaa tacaactgcc ggtcctcccg gccattatcc aagcggacct acatcgatta
     9661 acccaagtga ttaccaacct cataaacaac gccgcaaaat tcacgacgca aggatacatc
     9721 ttgattaaat acgattatac gcaagataaa cgttggatcc agatctccgt gaccgatacg
     9781 ggcaaaggca ttcccgcaga taagcaagcc caagtattcg aacggttcaa caaactggac
     9841 gagtttgcgc aagggacagg cctcggactg gcgatctgcc aaattatcat cgagcacttc
     9901 ggaggatata tcaccctaga atccaaagaa ggggaaggta gcacattcat cgtgaccctt
     9961 ccctacactc ccggattatc ggtataagat tattttttct tgaaacgcaa gaacggcaat
    10021 acaataaata aaggtatgca acagatcatt acccagataa agaaatgttg gtaaccgatc
    10081 tgctcctgta tccatcccga tgccattccc ggtagcatca tgcctaacgc catgaaaccg
    10141 gtactgatcg cataatgcga agtcttatat tccccctcgg cgaaaagcat cagatacatc
    10201 gtataagccg taaagccaaa cccgtagccg aattgctcga cagcgacaca agcgtttacg
    10261 acaacaatac tctccggcat cgtataggcc atatacaaat agaccagatt cggcaaggag
    10321 atagccaatg ccataggcca taaccaagtc ttcaagccac tccgggatat agccaggcct
    10381 cctaaaaccc ctccgagcaa taaggagatc actcccaccg taccataagc gaacccgacc
    10441 tcaccggtac tgagcgccag cccgccaact tcccgcccat ccagcaggaa aggagaagcc
    10501 aactttacca attgggattc ccccaaacga tacgtcagca taaaaagcaa agccgggaca
    10561 atccctttct tgttgaaaaa actcacgaaa gtattgccaa actccaccaa gatggtatga
    10621 ggggtgatat tcgtacgttg cgcatcactc gccggacggg gtaagatata cttatgccac
    10681 aaggccaagg cgataaaggt accggccaat acgaaaaaca ccaggctcca agcaaaggaa
    10741 atccgcccgg tactctcctc caaaagtccc gccagcataa ccagcagacc ttgtccggtt
    10801 agcatcgcca ccctgtagaa cgtatttcgg ataccgatga agaacgcctg ttgctcctcc
    10861 gtcaagccca gcatatagaa cccatctgcg gcgatatcgt gcgtagcgga actaaacgcc
    10921 atcaaccaaa agaaagccaa ggtaaaccgc agaaagaaat ccccgggaag gacgaacgcc
    10981 acacctgcca ttcccccacc aatcaataac tgcatgccat aaatccacca acgcttcgtt
    11041 tttatcaagt ctacgaacgg gctccagatg ggcttgatca cccaaggaaa ataaagccaa
    11101 ctggtaaaca aggcgatatc cgtattcgag acgcccaaac gtttatacat gatcacagaa
    11161 agcgtcatga ctaccacgta gggcaagcct tcggcgaaat aaagagacgg gatccaagcc
    11221 caaggactac gtttttccat aatcagcagg aatcagatga ttagaagtca atactaaatc
    11281 catccgcatc cttccacgcc gggaacttag cccggaactc atccagctcg ctcttcttca
    11341 aggtacatgt ccgggtgatt tcctcccgtt ttccggcatc agccaatttc tttccttttg
    11401 cgttataaat catggaatcc cctctgaaaa gaaaaccttt cccatctacc cccacacggt
    11461 tcacgccaca gacataagcc atgttctcaa tggcacgggc atgcagcaat gccttccacg
    11521 ccttcttccg ggcctcgggc caattggcca cataaatcaa aagatcatat tcgttattta
    11581 cgttgcggct ccaaaccggg aaacgtaggt cataacaaac ctgcaaacag atattccagc
    11641 ctttataggg cacgatcagc cgtttgtcgc ccgccgagaa atgcttgtcc tcttccgcca
    11701 tacggaacaa atgacgctta tcgtaataat actcctctcc ttccggagtg atgaaaaaag
    11761 cccggttgta gaactttccg ttatcttttg cgataaaact cccggccacg gccagtttat
    11821 atttcttagc ccattccttt atagtcggta cggtctggcc ctccatcgta tcggcttgtt
    11881 tctccacgtc catggaaaat cccgtggtaa acgtctccgg caatacagct aaatcggttc
    11941 ttccactaac acggcgcaac agttcgccgt aataacccaa gttctcttca cggtcttccc
    12001 aaatgatatg ggattgtatc atgctgatac gtaagtcttc agtcatagaa taaagatatt
    12061 aaggtaataa aaagacatat tgtgacaagg aaacagtttc atggtgaaga aacagtagtt
    12121 tcttcatagc aaaacttttg tttctcttag ggaaaacttt tgttttccta tagtaaaact
    12181 cttatttctt caccataaaa ctcctatacc tgtacgaaat tctcaggatg gcaagcggta
    12241 actccccgat acatctcacg tatcgtatgg atatctttat ccacatcacc tgtcggataa
    12301 aaaacacctt tcgtacccac ctctttcttt ccataatcaa aataagccac cacgatcggc
    12361 acgttcgctt tcaaagcgat aaaatagaat ccttttttcc agtccttggc ccgcttccgg
    12421 gtaccttccg gtgtgacggc caattgaaac cgctcactgg tcttgaaacg ttccaccatc
    12481 tgatcggtca ccgacgtacg tttaccacga tccaccggaa cacctcccag ccagttaaac
    12541 agcaaattaa aagggaaaaa gaaccactct ttcttaataa ggaaaccggc gttacacccg
    12601 atcgaggtat aaaaaagttt ccctacgata aaatcccagt tactggtatg cggagccaca
    12661 catacgatac atttcggcaa atccacgcca tccaccgggc ccagcttcca ccccgccata
    12721 cggagtatcg ccttactaat tgccttcttc atgcctattt gtccttgctc aactctccta
    12781 tctcgtcggc gatagcgtta acctcgtttt gcaagtcctc tcttaatttg cgataataat
    12841 tccgtacgag agccttgtta tccttgccgt cggggtgtcc ggcacgaacg atataactat
    12901 cttgcatatc taggatacga gccatcaaag catccgcttt ctcttgattt actccgggta
    12961 tatacaattt gcaaaccagc gcttccgtga acaattcacc agccacgtag ctgatctctt
    13021 tctttaaaat tcttctttta gccataatta tttcatattt aattatccac aaatatagaa
    13081 catatgttat taaataccga ggaaaggcca agaaaaaaca taaaatgaat tatctttgca
    13141 gcggtgaaat cattgattat aaacaaatca aatatgaacg aaatgataaa gacgccagag
    13201 tttctctttg aaagcagctg ggaagtctgt aataaagtgg gaggtattta taccgtacta
    13261 tcgactaaag ctcatacgct tcaacaaatt tttaacgaca aagtaatatt catcggtccg
    13321 gatgtgtggg caaacacaac cgctcccgat tttacggaag acgcatcttt gtttgaggat
    13381 tggagaaagc acgccgaggc agtagatcac ttgaaagtta aggtcggtcg ctggaacgta
    13441 ccgggtaccc cccctgttat actggtagat ttcaagtcct acttcagtga acgagacgcc
    13501 tttttctatt ctatgtggga aaatttccga gttgactcca tccacgccta cggcgattac
    13561 gatgagtctt gtatcttcgc gtatgcggtc ggtaaggtaa tagagagttt ctatcacttc
    13621 tacaaactgg aaaacaagaa agtcgccgcc ctattcaatg aatggatgtt ggcgatggga
    13681 gcgctttaca ttcaaaagca aatccctgcc atagcgacac ttttcacgac gcatgccaca
    13741 tcgatcggac gctctatcgc cggtaacaac aaagcgttat acgcttatat ggacggttac
    13801 aacggcgatc agatggctaa gaagctaaac atggaggcca agcattccgt agagaagcag
    13861 gccgcccatt acgtggattg cttcacgacc gtaagcgata tcacggcccg tgaatgtaaa
    13921 cagttattgg ataaggcacc ggatatcgtt accccgaacg gctttgagcc caacttcgta
    13981 cccgagggta aggaatacgc taaaaagcgg aaggaggcac gtcgtacatt aattaatgta
    14041 gcggagaaat tattgggctg ctccatcgac ccgaacgctt tgctggtttc caccagtggc
    14101 cgctatgaat acagaaataa aggtatcgat gtcttcatcg aggcgatgaa ccgtgtacgt
    14161 acgtccggac gcctgcagcg tgaggtcgtc gcctttatca tggtaccggc ttgggtacgt
    14221 gctgcccgtg cggatttaaa agaggcgatc gagcaggaca taaagacgac ctctccgctt
    14281 caaatccctt tcattacgca ctggttgcat aatatgccag aagataaggt cttgaattat
    14341 atcaaccacg ccggcttcac gaacgcggca tccgaaaaac taaagatcat attcgttcct
    14401 tgttatttgg acggtaaagg aggtattttc aataaggcct attatgatat gctgataggg
    14461 atggacgcta ccgtatatcc ttcctactac gagccgtggg gatatacccc gctggaaagt
    14521 atcgctttcg gtataccgac gatcacgacc aatctggctg gtttcggtat gtgggcgaag
    14581 aaaacggtat ccggagataa ccttagcgaa ggcgtagagg ttattaatcg tacggatttc
    14641 aattattttg aggtagcgga cgctatcatg aactccatcc tggctctcag ccaaaaggat
    14701 gctacggaca tcgaggaaat caaacagcgt tgtttcgatc tcgctcgaaa agctgaatgg
    14761 agcaagttta tcgactatta tctgaccgca ttcgacatcg ccataaagca tgccgaggaa
    14821 agaaacagct aaatattgct cataattaat aagataatgc tatctttgca ctcgttttta
    14881 gacaaacact ttaaacttca cgataatgaa aattaaggcg aataacgcaa acagtcctat
    14941 ttggaaggac gtctactcac attccaagct tccacaacag ttggaaccac ttaatgagat
    15001 cgctacaaat ctttggtggg tatggaatca tgaaggcgct aaactatttg gcaagatcga
    15061 caaacaactt tggaaatcca cagaaggtaa ccctgtacag ctattgcaaa gcctttcaca
    15121 caaacgtatg gaagagatct tagcagataa ggagttaatg gctgaaatcc aaaaggtata
    15181 cgctgatttc aaagcttata tcaatgtaaa acccgacaag acacaaccgt ctgtagccta
    15241 cttcagcatg gagtacggtt tgaccaatgt attaaagatt tactcaggtg gtctgggagt
    15301 attagccggt gactacttga aagaggccag cgatagtaat atcgatttat gtgccgtagg
    15361 tttcttgtat cgttacggat atttcacaca gactttgtct atggacggtc agcagatcgc
    15421 caattacgag ccgcaaaatt tcaacgccct gccgttgact caggtattgc agtcgaacgg
    15481 agagccgatg gtattggaag ttccttatcc gggcagaacc gtttacgttc atatctggaa
    15541 agttagcgta ggtcgtgtac ctttgtactt aatggatacg gatattcctc agaacagcga
    15601 atgggatcgt tccatcacgc accaattata tggtggcgac tgggagaacc gtatgaaaca
    15661 agagtatttg ttgggtatcg gtggtatcat gatgctgaac aagttaggta tcaagaaaca
    15721 aatttatcac tgcaacgagg gacacgccgc tttgatcaac gctcagcgtt tggtagacta
    15781 tatccagaac gacggccttt cattcaacca agcgttggag gtagttcgtg cttccgccct
    15841 ctatacggta cacactccgg ttccggcagg tcacgattac tttgacgagg gtttgttcgg
    15901 acgttacatg ggtgagttcc ccggcaagtt aggtattagc tggcaagatt tcatcgacat
    15961 gggacgtgag aacccaggtt ctaacgagaa attctccatg agcgtattcg ccttgaacac
    16021 ttgccaagag gctaacggcg taagctggtt gcacggtaag gtttctcagc gcatgttcgc
    16081 cccggtttgg aaaggttact tcccggatga actgcacgtt ggttatgtaa cgaacggtgt
    16141 acatatgccg acttgggccg ctaccgaggt gaagaaattc tatgcggata aattaggcac
    16201 gaagcttttc gaggatcaat caaatcgcaa atgttgggaa ggaattcaga atgtatccga
    16261 cgaggaaatc tggaatctcc gtatgacctt gaagaataaa ttgattgatt acatccgtgt
    16321 tcaatataaa gatagctggt tgaagaacca aggtgatcct tccaaggtgg tttctatcct
    16381 agagaagatc aacccgaatg ccttgctgat cggtttcggt cgtcgtttcg ctacttacaa
    16441 gcgtgcgcac ttgttgttca cggacttaga ccgtttggct aagatcgtta acaatgagaa
    16501 gttcccgatt cagttcgtat tcaccggtaa ggctcaccca gctgatggtg gtggtcaagg
    16561 tttgatcaaa cacatcgtag agatctctcg ccgtccggag ttcttaggaa agatcatctt
    16621 cttggagaac tacgatatgc gtttggcccg tcgtttgatt tctggtgtag acgtatggtt
    16681 gaacacgccg actcgtccgt tagaggcttc cggtacttcc ggtgagaaag ccgagatgaa
    16741 cggtgtattg aacttctccg ttcttgacgg ttggtggtat gagggttacg tagaaggcgc
    16801 aggttgggca ttgaccgaca agcgtactta tgagaaccag caataccaag accaattgga
    16861 tgcggctacg atctaccatt gcttggaaac tgagatcatc ccgacttact acgctaagaa
    16921 cagcaagggt tactctccgg actggatcca atatatcaag aactctatcg ccaagatcgc
    16981 tccggattat acgatgaaac gtatgttgga cgattatgag gatcgtttct atcacaaatt
    17041 ggctactcgt tccgctcata tttccgctaa caactacgag atcgctaagc aattagctgc
    17101 ttggaaagag gaagttgcgc aacattggga tagcttccaa gtggaatctt tcacttgcga
    17161 ccaagatttg acggtgaatg gcccggttgt aggaaaagaa tacaacttca atttggtaat
    17221 cgaccgtcat gaactacaag gtatgttagg tgctgaaatg gttgtcatga aggaagatcc
    17281 ggagaaacac acgctgtcac caatcaatac cgctcagttc gagttgatga aggaagaagg
    17341 ctccaagtta ttcttcaagt taacgaccac tccttccgag gctggtaacc ataagatagg
    17401 cttccgtgta tatcctgtaa acaaggagtt gcctcaccgt atggacttcg cttatgtacg
    17461 ttggattcag ttataatcgg caacaagtaa aacaaataat caagaaagag gatgcgtcat
    17521 gcaccctctt tttttatgcc atacccagct atgctttaca gcgactaaaa cctatggtta
    17581 cgagccgtaa tgcatagggt ttcatatagt ccgttgaata cccatgaatt aaaaaaagga
    17641 agccacacga caggcagctt cctttttcaa taggatacga atattttcaa gcttagaaag
    17701 cgtagtccaa acttaatccg aacaccttgt tggtgcggct atacacattc tgcccaggaa
    17761 gtcccgtgcc gcagtagttg tccatcttct tggtataatc gtggtaagtt gtccacatat
    17821 atcccacgtt caaagccatt ttttcgctca acatcacttt agcaccaaag cccagcgaat
    17881 aagaatcgca ggagaaacta acatcacttt ggaaattatc agacaaacca taatctgtaa
    17941 tttgagcgcc accgctaatg gtcaatctct tgacaacatc ccactctata ccaaacagat
    18001 actcattcgt acctctttcc agttccttct gctttccacc ggccattccc gccttcttat
    18061 catcgaagaa gtgatactca acagaagcct tcaacatggg caaaaaccga taagaagctg
    18121 ccaccgaaag catggaagga atatcgttcg gcgtatttac accatgctta taagggccaa
    18181 ccaaaccttc cgcactgtcg ggataatcca acttcttggt attgttttcg atgttcaagt
    18241 tcgtcttaaa ctcatattta gctccgaaat tgaatttacc atatttgaca tcgacaccca
    18301 aaaccggagt caacccccaa cctgtctggt cgcaatccaa agccaggttc attaaatctg
    18361 ctccaccaaa attctgtttt aattttgcat ccagataccc gtcatagttt cctgagaaat
    18421 agttcatccg gcctccggca aaggcagaaa gccaatccgt gatcttgtat gacaggccaa
    18481 gttgtaggga ataaatatac tgttttccgt ccatcgcact gttaatagta tacatatccg
    18541 gcgtgacgat gggactttga ccgccagtct ttatatattt cgctacactt tcctggaaga
    18601 taccggccat agcagccgat tcgaacattg gcagaccatc gtcaaacgaa gccttaccac
    18661 ctccacccgt aatggcaaag aaaccggaga tcgtccaatc accttttttg taagccgcaa
    18721 aaacactcgg aatcacggga gcggcagcct ttcctttgta atacttttta tagggaacgt
    18781 cgctcactgt cggcacctta ttcactgggt cgaaaccatt gtatgtactg aaagaggcat
    18841 cgatatcccg ggtctggaaa gcactttgga tactcacacc aacgcggaaa ccgtctgtcg
    18901 gcaaaaaaga aagacccgcc gggtttgaca aagcgccgtc tatatcaatt gcagcacctc
    18961 gcgaaagtga ccttaaaaag gctgcatgct gattcgtatt cgtcaaatat cctccagcga
    19021 aagaaaccaa aggcatcatc atcaatgccg cacctaatac tacttttttc ttcatgtttt
    19081 acttttcttg attacaaaac ggtcgcaaag ataaatactt ttttcaaaca ctgcacactt
    19141 ttaataaaaa tgtgccgcac aaaacaacaa atactgtgca aacacataag actaattaac
    19201 aatagaagag ctgcaaaggt agtaacgtga aatcatgtat tagttataat cagcaagaat
    19261 catcctaacc tgaaaagaat atatacagca agtactaaag aagatatact tactttaccc
    19321 aaaaagatat actacaagtg ccaagtaagt ataacttcta tttttccgaa ataaatcgta
    19381 tatttgtctc tataacttaa ttctttaaac cgtatagata aaatgaaaag actagcatta
    19441 ctcgcggctc tcttactgcc gctatccatg gctttcgccc aacagaacgt aggattcaag
    19501 accgataagg tagaacctct cgtgatcaac tcagacaata gcgttacttt ctatgtagaa
    19561 gccccaaaag cgaagtccgt ctccgtaaaa ggagactggg aagccagcga gggcaatggc
    19621 cagatgacga aagggaaaaa cggtacatgg agctatacga ctcccccact gccatccgaa
    19681 atgtacacct atcgtttaaa tatagatggt atttacaaca tcgccccaaa caacccattc
    19741 tcttgccgtg acgtaggcac cttgttcagc ctgttctata tcaacggggg aaatggtgat
    19801 tattatcaag tacgtgacgt acctcatggc aatgttacaa ccacttggta tcactcggac
    19861 atcctcggga gcgaacgaag acttagcgtt tatacgcctc ctttttacga taagaacatc
    19921 cagtcttatc ccgttctgta cctgttacat ggcagtggcg gtgacgagaa cgcttggctg
    19981 gagcttggcc gtaccgcccg tatcatggat aacttgattg ccgaaggcaa gatacagcca
    20041 atgcttgtcg ttatgccaaa cggtaatccc agcaaacagg ccgctcccgg cgaaacgccc
    20101 gataacctga attacaagcc ggccatgagc aacagcttcc ccggttataa ggatggctcg
    20161 tacgagaaga gtttcaccga gatcattcat ttcatcgata accgttaccg tacgatcccg
    20221 gataagcgac accgggccat agccggactt tcgatgggtg gtttccatac attatatata
    20281 tcattgaatt atccggacta ttttaactat ataggacttt tctccgccgg actcagcgcc
    20341 aatggtgtag acccgaatag cccgatgtac acgaatctcg acgagaagtt aggaaacctc
    20401 aagagatccg gttatcaatt gttctggatc ggtataggaa aggacgattt cctgtacgac
    20461 gcaaaccagc aattccgcca gcgaatggat agcctaggta tgaaatacca gtacgtagaa
    20521 tccacccgag ggcatatctg ggccaattgg cgggcttatc tcctccaatt cgctcctatg
    20581 cttttcaaat aaaagacatg agcagatgaa tcttaatata ccgcaatacg acttctataa
    20641 acacaaatac ggcgatgagc tacttatcga cgtcgttccc ttgaacacga tcaagaagta
    20701 tctcaaggaa caacccgtac atatattgac gtattacgat ataacattga tcactagcgg
    20761 ggagggagaa tttcttatcg atcatcaagc gaaccgggta aagcctcaag atatcatctt
    20821 tacccggccc ggcgaaatac gtaaatggga cgataaaacg atacaagacg gattcgctct
    20881 tatctttgag gaagagttcc tgctctcttt tttcaatgat ccggcatttc tccggaacct
    20941 ctcttatttc catacggaaa gacggtcttc caagctcagt ctcgacaaga aagcctatgg
    21001 ccgcatctcc gagttgatct cggagatcga taaagagatc aaggactatc agtcgaaaga
    21061 caaacacttg ctccgggcct tgttgtacga gacattaatg ttgctcaaca ggctatacgc
    21121 tagctcgaac gctttacctc cagacacaaa cgcccgatct aaaagcatct atgtagaccg
    21181 atttatcgag ttagtaaacc attccttcaa gcaagatcat tccatccgga gctatgccga
    21241 tcggctttgc atcaccccga actatctgaa tgagatcgtg aaaaacgcta cgggtatcag
    21301 cgcaaaacaa tatatcttaa ataaaatact gatcgagagt aaacggctat tgacttatac
    21361 agacttgcct atatccgcca taacggaagc tctaggttac gaggatccat cctatttcat
    21421 ccgtctattt cgttcccaaa caaacatgac cccgctaaac tatcgcagga atacaaaacc
    21481 gtaaaaagta ctatttcctc ctttatacgt attatacgaa ctccattcgg tatgtctaat
    21541 tttgcctcta tcaataaata aagcatcatg agacaataca aatcatggat agcggctctc
    21601 atattaggaa gcacgttatc cactaacgca caacaaaaga atatggagaa caaaacatta
    21661 aacgagaaca tcccggagat gatcatctcc cttgaaaaag aggccctagc ctcgaccgac
    21721 ccgatggcat tcgtagagct ttcagacacc gacgtgattt acttcgatcc ttccctagag
    21781 acgaaaatag agggattgga acaactgcgc acttattata aaggtatgca acttcctccg
    21841 gcggatcatt tcgacatgat ccgcccgatc gtacaagtca cgcaaaacat agcggtcctc
    21901 acgttcaacc ttgatagcta cttatccgac aaggtaataa aatggaactg caccgaggtt
    21961 tacagacgca accccgacaa ccagtggaag atcatacaaa cccactggtc ttacgtgaaa
    22021 ccgatagatt aaggttaaaa catttgccgc tttctgaacc aaaacggttc gcaaaatgta
    22081 ttatatagac tattcactaa acacaaatta tatgatacgg aatttactga aagcggcaaa
    22141 tgcgcttaca tttagcacga tgttcctgtt actcctcgcc ggatgcaaca agaacacgat
    22201 tatttttgag gatggaacaa gcccgaacgg ctcttcggga aacgaggacc cgggaaacag
    22261 tacgttggtg accttcaacg cctccgtgga gggccggaac ctattacgtt ccatgtctcc
    22321 catgaataaa gggatacaaa gcagggttta tgtcttcgac agcagcgcag gaaccaaggg
    22381 aagccccgag gcgtcaggcc tttacataac ctcatctccc ggggtattaa caggaagtga
    22441 cggatataaa atgtttctct ccaatggcac ttataatttc tacgccgtat ccgacaattt
    22501 ctccacgatc cccccgacat tcacgagtgg cgtatccgaa cccctcttca acggtatcga
    22561 ttatctttgg tggaacgcca tacaacagga tgttaatagc tcccaaatca atataccgat
    22621 tgtttatggg catgtggcta cccaagtcgt agtagaatta accggcggtg aaggcatcac
    22681 gatcaaccaa ttggtctccg ccatgatcac acctcccgaa accggggcga ccatggatct
    22741 gggcacaggt atcatcactc ctgctaccgc tttcgggaaa gcggataaga tggggataaa
    22801 cggattaacc gcccaatata tcatgttgcc gataagacat acggctccca tgactctcac
    22861 gttggaaata tccgccgaca atgaaaacag cacccgtacc tacaccaccc aagtgcccct
    22921 tccggatggc gagttgaaag cgggaaactc ttatttattt aaagcggtaa tcaacggtaa
    22981 ttcggtcact ttggccagtg tcaacgtaaa agactggaca gatgtggacg agacaggaaa
    23041 gcccctttat ccgacccaga attaaagtcc ggttcctatt ttccgtatca atgaatattg
    23101 gtacggaaaa tatgcctata tttaccccgt cacctctaaa aacaatacga atatgattga
    23161 gattcccgaa tccgccacca ttggcaaaca ggctagcgaa acgctaaagg gtaaacggat
    23221 agcgcatgtt atcgagtcga acagtcctca ccgtttcacg ttctataatg gcgatccggc
    23281 ggaatactcc aataggctgg taggacgaac ggtcctaggc gcccaaggct atggcgcatt
    23341 cgtggacatc cttatggacg cagataccca cctcttgatc ggagacggaa ccaatatgcg
    23401 ttattatacc tccgcggaaa aggccccgaa gaaatatcag cttatgatcg tattcgagga
    23461 cgactcgttc ctagctttca cggtttcgat gtatggttcc atctacgctt tcaaaggcga
    23521 gtttgacaat ccctattacc aaggtagcat ccataagcta tgtccgttgg acgagagatt
    23581 cgataaagcc tattttatca gtctcatccg gaatctcaag aaagatatat ccgcgaaggc
    23641 gttactcgcc accgagcaac gtattccggg cctgggcaac ggagtctgcc aagatatctt
    23701 gttcaatgcc cggatctccc cgaaacgaaa aatatcgact ttatcagaag aggatataga
    23761 cagcctcttc aacaccgtga aatccacgct ggaagagatg acttgccgag gaggccggga
    23821 tacggagaag gatctatacg gcgccttagg caattaccgc acgatcctat cgaagaacac
    23881 ctaccatgac ccttgccccg tctgtggcga acggatacag aaagaggctt acctcggagg
    23941 cagcatttac tattgcccgc attgccagc
//
LOCUS       DBMDTB010000063        23920 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_736_length_23920_cov_11.581385, whole genome shotgun sequence.
ACCESSION   DBMDTB010000063 DBMDTB010000000
VERSION     DBMDTB010000063.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 23920)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 23920)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23920
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_736_length_23920_cov_11.581385"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(26..1042)
                     /locus_tag="ACZPB4_10935"
     CDS             complement(26..1042)
                     /locus_tag="ACZPB4_10935"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRM11 family methyltransferase"
                     /protein_id="HIR1098761.1"
                     /translation="MYKRTIDNRWSFKDADTKEFTHCYHAYPAMMIPQVARALIEEYR
                     PEDGVELLFDPYMGSGTSLVEASIKGINAIGTDLNPLARLMSHVKTTHYDLSCIRDTF
                     SMMQVLFFEYSEDKVKNKNFDNISNYTYWYSRDSLLRLSYIYQVINECVALDFADFFK
                     VPLSETVREVSFTRNGEFKRFRMKEEKIKDFKPDVFRLFEEKVIRNINGLEEFNSIKY
                     PCNIGIYDFNSTIEIPSDIIQPNSVDMVVTSPPYGDSRTTVAYGQFSRWANEWFNFEN
                     AKTLDNLLMGGRVQKEELFETKSIKSELDEIKSIDPKRNLEVVSFLNDYSCSIKNVAS
                     VIKR"
     gene            1148..1441
                     /locus_tag="ACZPB4_10940"
     CDS             1148..1441
                     /locus_tag="ACZPB4_10940"
                     /inference="COORDINATES: protein motif:HMM:NF024835.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HIR1098762.1"
                     /translation="MIRKTEYQLEIILKIKELREANNVSQKELSNLLEVAPGLIGSIE
                     SPKFPHKYTLSQIYKICHYFNITIEQLFISEEDFSKDRDIIDLLIFNIIRYGE"
     gene            1431..2177
                     /locus_tag="ACZPB4_10945"
     CDS             1431..2177
                     /locus_tag="ACZPB4_10945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MvaI/BcnI restriction endonuclease family
                     protein"
                     /protein_id="HIR1098763.1"
                     /translation="MENKDFIISKFKEVKSLEYVPSNRANNTGIGKTFEDYIGVVENN
                     LDEPDLAGFEIKSHRGASCSYVTLFTKSPSFPKRANAYLKDKFGTPYEDAPSINSLHT
                     SMFANSYNTYMKKYSFKLLNNPVAKTILIGVFDLNTKELLDCSVGYTYQDIQKALTKK
                     LKNLLYVTAQTKKEGGKELFYFNKADIYTEPSFERFISLLTDGKIMYDIRIGSYKSGP
                     KYGMPHDHGSGFRILEANIRLLYSDHETIE"
     gene            complement(2254..3213)
                     /locus_tag="ACZPB4_10950"
     CDS             complement(2254..3213)
                     /locus_tag="ACZPB4_10950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PCMD domain-containing protein"
                     /protein_id="HIR1098764.1"
                     /translation="MVVNNRLGYLFVFLGMSMALYAQRKTEAIRYGDLDQWVVRKITE
                     SAIIGKETKTLYCVGPTDTIIGNRPFESKASPWGSSNVMARVSGITKASVSVYPERRD
                     EGYCARLETGIESISAMGIMNVKVLVGGCLYLGHFLEPAKNSSETWGQIVCGIPFHQK
                     PTSLLFDYKVKLSGDPNRIKLSGFSKRSEVDGIDMPLVNLFLQKRWEDKDGNIYAKRI
                     GTLVIRMDENTDWVNDASFTILYGDITKRSDYEEYMGFQLGESARYSLNSKGKNVPIQ
                     EIGWGTEDDEVTHMILEFCSSHGGSYIGSPGNTFWVDNIRLGY"
     gene            3346..4788
                     /locus_tag="ACZPB4_10955"
     CDS             3346..4788
                     /locus_tag="ACZPB4_10955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC family protein"
                     /protein_id="HIR1098765.1"
                     /translation="MAEKPRTPSIAISLLPVVTLVIMLAVAIYIFRGDSLGGASQIVL
                     LIATSICSLIAVFHCKIKWEDIEGQIARNIYGIAPSVIILLLIGTLSGSWMVSGIVPS
                     LIYYGLQVMQTDFFLVACCLLCSIVSVMTGSSWTTIATIGIALIGIGEAQGFSTGWVA
                     GAIISGAYFGDKMSPLSDTTVLAASVTDTPLFTHIRYMLYTTVPSMIVTLIVFSIAGF
                     SRETADASQIAAFSEALKGSFHITPWLMIVPIVTGIMIAKKTPSIVVLFASSILAGIF
                     ALIFQPNALLEISGITDSGIIAYIKGLLMTFYDSTQIQTGNEALNSLVSTRGMAGMMN
                     TIWLIICAMCFGGAMSASGMLESITRIFLHFMRGRTSMVASTVVSGLSLNICTADQFI
                     AIILNSEMFKEVYKQRGFESRLLSRTTEDSVTVTSVLIPWTTCGMTQSTILGVSTWTY
                     FPYCVFNIVSPFMSILIAATGYKIVQKTVK"
     assembly_gap    4790..4889
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            4930..6396
                     /gene="nhaC"
                     /locus_tag="ACZPB4_10960"
     CDS             4930..6396
                     /gene="nhaC"
                     /locus_tag="ACZPB4_10960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HIR1098766.1"
                     /translation="MENHLKKMPSPLLSLVPILVLVALLFVTIRTFGSDALSGGSQVV
                     LLTTTAVASLLAMIFCKVKWRDIEEAICKNILGVATAIIILLLIGALSGSWMISGIVP
                     TLIYYGMQIIHPSFFLASCCVICAVVSVMTGSSWTTIATIGIALMGIGEAQGFATGWV
                     AGAIISGAYFGDKISPLSDTTVLASSVTHTPLFSHIRYMMLTTIPSMVITLIIFTIAG
                     FTHTSNASGQIAEFAASLNESFNISLWLLIVPVVTGILIAKKVPSLITLFISTAMAGG
                     LEIFFQPHLLQEVAGASVADASSLFKGLFMTFYGSTQIDTGNEALNSLVATRGMAGMM
                     NTIWLIICAMCFGGSMTASGMLESLTSVFLRFMKRRVGMVASTVFSGLFLNIVTADQY
                     ISIILTGNMFKDIYKKKGYESRLLSRTTEDSVTVTSVLVPWNTCGMTQATILGVATLT
                     YLPYCFFNLISPLMSITMAAIGFKIKQHHEEDQSIIVN"
     gene            6365..7537
                     /locus_tag="ACZPB4_10965"
     CDS             6365..7537
                     /locus_tag="ACZPB4_10965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="HIR1098767.1"
                     /translation="MKKIRVSLLTKVVIAIAAGVLFGQFLPGGIARIFVTFNSLFGNF
                     LSFSIPLIILGLVTPAIGDLGKGAGKLLLITALIAYGSTVFSGFFTFLSGSAIFPHIL
                     PTNTELTAMENPEDFMLTPYFVVNMPPLMDVMTALLLSFTIGLGLSNIAGTTLRDSFT
                     DFKEIIIKLIEVVIIPLLPLHIFGIFLNMTVSGQVMSIITMFLKVIIVIFVLHVLLLL
                     IQFTIAGAIAGKNPLRLLKNMLPAYATALGTQSSAATIPVTLAQAVKNGVRENIAIFT
                     VPLCATIHLAGSTMKIVACAMAIMIMAGEPVTFSNFSGFIMMLGITMVAAPGVPGGAI
                     MAALGILQSMLGFNETLQALMIALYIAMDSFGTACNVTGDGAIAVVVDKIAGKNTP"
     gene            complement(7538..8083)
                     /locus_tag="ACZPB4_10970"
     CDS             complement(7538..8083)
                     /locus_tag="ACZPB4_10970"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HIR1098768.1"
                     /translation="MERFAAIDFETANGKRSSICSIGIAILEDDWVVDSIYTLVRPTP
                     NFYTRWTTAIHGLSVEDTNDALCFEEAWESIAPKLKDLPLVAHNSPFDEGCLKAAHEV
                     YDLAYPKYPFYCTCRLSRKMYPFLVNHQLQTVAAHCGYDLTQHHNAMADAYACAHIAL
                     TMMREKEVDTLEALMASCYSR"
     gene            complement(8164..11397)
                     /locus_tag="ACZPB4_10975"
     CDS             complement(8164..11397)
                     /locus_tag="ACZPB4_10975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S41 family peptidase"
                     /protein_id="HIR1098769.1"
                     /translation="MRKRMILTALAAVAIPTLLMAADEARLMRFPATNGSEIVFSYAG
                     DLYKVPATGGEAQRLTSYVGYEMFPRFSPDGKTIAFTGQYDGNTEVYTMPSSGGEPLR
                     ITYTATNSRDDLGDRMGPNNIVMTWTPDGNGIVYRNRISDGFSGKLYTVNKEGGLSEV
                     VPLPEGGFCSYSPDGKQLAYNRVMREFRTWKYYKGGMADDIWVYNPEKKSVENITNNE
                     AQDIFPMWIGDEIYFLSDRDYTMNLFVYNTKTKQTSKVTNFTEYDVKFPSSFGNTIVF
                     ENGGYIYKMDAASKKPEKVNVTLASDNVYARSEIKDGSKYITSASLSPKGERMVVTAR
                     GEVFNIPVDKGVTKNITRTPGAHERDAQWSPDGKHIAYISDATGETELYLQDSEGGEP
                     TQLTKNNDTYIRTFQWSPDSKKIVYTDRKNRINLLDVSNKQLTTISQSLLGEARNVSF
                     SPDNNWLTYSRVSDNNFSIVYVYDIAGKKEYPVTDKWYESYSPVFSTDGKYLVFTSAR
                     DFNPTYSQTEWNHVYNNMGGVYLALLSKDTASPFMETDAEVAIESTPAKADASKKDET
                     KNEASTPVVKIDIEGITDRIVKLPLPGSNYYDLYSDGTNVYYFTKGGMKMFDLKKQKE
                     ETVSDAAMMVDPAGKKAVFFKDDQLFVTDIPKGKADLSKPVNLANMKITVDYTKEWAQ
                     IFDEAWRAFRDGFYLENMHGKDWKAIKEKYAALLPYVKTRLDLNYIIGEMIGELGVGH
                     AYVNPGEVESPKRVSMGLLGAEVSRDKSGFFRLEKILPGASWSKELRSPLTEPGVEAK
                     AGEYIVAIDGVPTNSVNDMYKLLIGKANVPTELSLNSKPQLAGARKIVVSPLAEEYSL
                     YHYNWIQDNIKKVDKATNGKVGYIYIPDMGPEGLNEFSRYFYPQLDKEGLIIDDRANG
                     GGNVSPMILERLSREPYRLTMRRGSSLIGTVPDAVQVGPKVCLINKYSASDGDLFPWG
                     FRALGLGKLIGTRTWGGIIGISGPLPYMDGTDIRVPFFTSYDPKTGNWIIENHGVDPD
                     ILIDNDPIKEWNGEDQQLDRAIEEVMKQLKERKPLAPVPAPRDWSHK"
     gene            11856..12140
                     /locus_tag="ACZPB4_10980"
     CDS             11856..12140
                     /locus_tag="ACZPB4_10980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007656303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015661 - L-lysine efflux transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:1903401 - L-lysine transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysO family transporter"
                     /protein_id="HIR1098770.1"
                     /translation="MFIILGLLGLGISVGYLCRHVPAFKGLEHSISYTIFAMLFIFGI
                     TIGANQSLLNNIGEFGIQAAILAICGVLGSLVASFIAYKLFIKKGGLNEK"
     gene            12130..12753
                     /locus_tag="ACZPB4_10985"
     CDS             12130..12753
                     /locus_tag="ACZPB4_10985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015661 - L-lysine efflux transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:1903401 - L-lysine transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysO family transporter"
                     /protein_id="HIR1098771.1"
                     /translation="MKNNLIVILCFTAGIFCGTFANTTISTYCEKLPQFLLYALVIQV
                     GLNLGANAELGKMVKDIRFSSLLLPFFTIIGTLVFSAAASLLLTSWNIYDCMAVGSGF
                     AYYSLSSLLIVQLKEASAGIEIASQLGAIALLANIIREMLALFGAPLYASFFGKFAPV
                     SVAGINSMDVCLPVISRYSGKNIVPVAIIHGIILEISVPLLISLFCK"
     gene            complement(12987..16439)
                     /locus_tag="ACZPB4_10990"
     CDS             complement(12987..16439)
                     /locus_tag="ACZPB4_10990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6383 domain-containing protein"
                     /protein_id="HIR1098772.1"
                     /translation="MNKKFSTLLAGMALLSVMSVNAQTTPSRVDPETVLGQEWRLGGL
                     KEGANSGLYQLKVMDGTTPAYLAMELNRGTGDYELRVYSASEAKNNLEATLWCVSVSN
                     YNQGQAPIYDFQNKLSGTMLDLTMAGHEKTENGTNGAWKPVLGGEIAGWAFSRSYKDL
                     EEKRPLYSYFSTDSIVGLKADPTTGAVKVAKWGANQIDATSNAADVTNFALVGAAQIA
                     LSEDQVNTKLGLLQDNKAGVQLTFTPDVKGTSLKNPFNEQKFIAEDKDNNKWLFIKQK
                     DKDAYLKVDTAYTNETGTKFLAYGWTEKAKDKADAYSSISSELRAQHQFKFIYSPSGD
                     SLYIYVKKVTWNNDGKYWNTHVTATPVNEHEFWRVSLQDLIKDETCILTVDPEDQNTH
                     ISLGLSGCEEKGSSKTSVDDGVYFIKNKQGQYLASPIYENGTIRWTTVNEDEQSVAHM
                     PAYQWVVLKKNTSNDKVKAVSPVTISNREFADKVINADFDGDGQMESYKTAVYSTVQL
                     RKAEGGSYMFVYGDKLTAEYGSVGIDSLFFEKVPAASISDPYLGYRKLEKDSLLVNKY
                     TFNYWHPYATDKYIAKSTDSTLTVLDGKDAFVIDTLTERWNNNSKIFATVDIPYGYKV
                     SDDVAKNRIKGLKTLVRTAYEVSYKDGKGELNEWKVNKEDKFNVGSSATGHQQSYTTY
                     YAFFKENNYISGKHYYAIVNAAYDNYSNATKYVLGYQKAGVSDYDGAATLKNQVLGET
                     RTSAFAIEPDNTPLYRRFSSLELEGNEGDKADTLRFIEKYRKEYLQVENNKNFMKEGI
                     DFLGIYTPDKTEDGLSFIVDTAWVNRGSGNIKPQYLISIDRNDFEGVEGVPCTEDDHH
                     FTAEGKPTDKWHCVHAKPAVPGFERGKYLINFHDFANKYGWSTLSNGEQDADYMWKKY
                     DRAGFVEAIRVADTLYILRDEFKNLPNEKINFADLNKAEEDAWTAAKKAGVSEDEFVS
                     HKYILSGDNHKYVTWSMRFVNKEVAANEVEADRAFLFESMKSKHVPGYNNSAMGDIAP
                     TYAAWLRMQNGCLVLSDDRSSNFDEMNTGGDDALIFNVEQGDDIATDNETIDAVEGIS
                     VVAGNGTVTVQGAAGKSVVITNILGKVIAETVLTSDNATISVPAGIVAVAVDGEEAVK
                     AIVK"
     gene            17070..17933
                     /locus_tag="ACZPB4_10995"
     CDS             17070..17933
                     /locus_tag="ACZPB4_10995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HIR1098773.1"
                     /translation="MAQYVDIMTDAGFKAVFQDKQVTIKFLNAALAGERQIKDITYLD
                     KEIKPEIVENRTIIFDLLCEDVSGAKFILEMQNCPQYYFFNRGFYYLCRMVARQGQIG
                     KQWQYRLLPIYGVYFLNFKLPEFTDFRTDVVLANERTGKVFNEIKMKQIYISFPLFSL
                     SKEECKSSFERWIYTLKNMNLFEQSPFKEEQETFLRLLDVANVNSLSEKERAIYEENL
                     KNYRDWYATIDYAQTEGIEKGMQEGMQKGIEKGRQEEKLQIAQKMKEQGLDSELIAQC
                     SGLSVEDIERL"
     gene            complement(18028..20097)
                     /locus_tag="ACZPB4_11000"
     CDS             complement(18028..20097)
                     /locus_tag="ACZPB4_11000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HIR1098774.1"
                     /translation="MNFKTAKMMTKYRVCMTFMSILLLLFHFVFLFSCGKLPEKTFAF
                     SDNLRIDSLEHMAMDSIYRNPRYAHSALDEALSLTKDSDKYYKLLAAKSQIYFANSVY
                     DSGFVLHRSIIDYCDRVPMSPKIHGLLGTLKNTVGNYYSFLDKTDSALLCYSEAYQEI
                     RQSEMEHKIPDIYINIADIYARKGAYDQRARYFRQALFVSDSLGIMDRMSFPIYFGLG
                     ETYMELRDFDLSDHFYRLAEKELDSRNLSEKFTFCNSRGNYYYYKEEYAEALPWFLKA
                     REVVRPTHMDFYTNVCEINLGEIYLCMDQLDSARFYLEKGFRYFHTYNNKTALYHLTT
                     LKASLALKEGNSGLAYQLLRSYTDTVGIDPKMVVIRNKNLQNYFATTGDFRRAYEYQT
                     KNSVIENNIRSERTQMRVAEIDMRYRQDTTLLKREAIIKQQAGRMEYLEMSRWVWILL
                     FAILSIVSGMAYYFMKRKRHAQWLSHIDQVTKLKMESIRNRVSPHFIFNVLNREISTE
                     EEGSLRRTQLSGLVELLRSSLEISEKLSITLREELRFVRTYLNLQTQALGPDFHLAWN
                     IDPSLDTDAIYLPAMLIQIPVENAVKHGLCAIEGEKRLSVFVERDGKGIHIRIEDNGP
                     GYRPFTNAGHTNGTGMGTKVLYRTILLLNRRNKEKITYSVQSKEKGMGSGTIVSFFIP
                     LDFNYAF"
     gene            20191..23421
                     /locus_tag="ACZPB4_11005"
     CDS             20191..23421
                     /locus_tag="ACZPB4_11005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S41 family peptidase"
                     /protein_id="HIR1098775.1"
                     /translation="MKNLMIPALALFLSAAAQADDSPLWMRYCAISPDGQTIAFSYQG
                     DIYTVPSSGGKARQLTTHPAHDTRPVWSPDGQKIAFASNRSGNFDVFLMNKEGGEPKR
                     LTTHSTNEYPTTFKDNGHILYLANILQDAKDIQFPGTRFMQVYEISTDGGRPDLYSSL
                     YMENIALSKDGSKLLYNDYKGYEDPWRKHHQSSITRDIWLCTLGKDRSFRKVTTFGGE
                     DRNPVWAADGASFYYLSEEKGSFNIFKKDLAGNSEKQITTHTTHPVRFLTSDNSGTLC
                     YSYDGEIYTVKEGQKPAKVNIQIVADKIENDVIHRLLTDGATDIAVSPNGKEVAFITR
                     GDVYVTSIEYETTRQITNTPQQERNIDFSPDGRSLVYSAEREGTWGIYESKLTRDEDK
                     QFTYAPELKEEPLVVSGQTSFQPLYSPDGNEVAFLENRTTLRVINRKTKQVRTVLDGK
                     YLYSYSDGDQHFQWSPDSKWFLVDYISVGGWNNTDIALVKADGSGEVTNLTESGYSDG
                     DAKWVLDGKAMIWSSDRAGFRSHGSWGAERDVYIMFFDGEAYDKFRLSKEELALVEAD
                     ENKDKDEDKTSDKDSDKKKEDKDKPVAPLKFDLENRKDRIIRLTANSSSLGDAVLAPK
                     GDKLYYCAAFEKGFDLWEHDLKEKSTKLLLKNVGRGTLFADKKVENLYLTAGGKLKKI
                     ELKDSKEKPIAFKAEFAYRPAEERAYIFHHAWRQVLDKFYDPTLRGMDWKGYETAYAR
                     FLPHINNNFDFQEMLSELLGELNGSHTGARYNPGLTGPETASLGAFFDNAYTGDGLKI
                     EEIIAKGPLTLADSQIKKGCIIEKIDGTPIKKDADYYPLLSGKVGKKVMLSVYDPTSK
                     QRFEEQVKAISNGEQSNLLYKRWIENCQETVDKLSNGQIGYVHVRGMNSESFREVYSA
                     LLGRCRNKKAVIVDTRHNGGGWLHDDLATLLSGKEYQRFEPRGQYIGSDPYNKWTKPS
                     CVLMCEDNYSNAHGFPWVYKTLGIGKLIGAPVPGTMTAVWWETQIDPTLVFGIPQVGV
                     KDMQGNYLENQQLQPDVEVYNTPEAQLSGEDTQLKRAVEVMLQTVK"
     gene            complement(23660..>23920)
                     /locus_tag="ACZPB4_11010"
     CDS             complement(23660..>23920)
                     /locus_tag="ACZPB4_11010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007655883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015661 - L-lysine efflux transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:1903401 - L-lysine transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysO family transporter"
                     /protein_id="HIR1098776.1"
                     /translation="QLAAELGTIALIANIIREIFALLGAPLFVRYFGRLSPICAGGAT
                     TMDTTLPIITRYCGKDLVFVSIFHGILVDFTVPFFVSFFCSM"
BASE COUNT         6671 a         5748 c         4904 g         6497 t
ORIGIN      
        1 ctgttccgga gacataccga ttccgctatc tctttattac agatgcgaca ttctttatag
       61 aacagctata atcattaaga aacgagacca cttccaaatt tctctttggg tcaatgctct
      121 ttatttcgtc cagttcagat ttaatgcttt tagtctcaaa aagttcctct ttctgaactc
      181 gtccccccat taggagatta tctagtgttt tagcattttc aaaattgaac cattcatttg
      241 cccaccttga aaattgtcca taagcaacgg ttgttctact atcgccataa ggcggagagg
      301 ttacaaccat atcaacacta ttcggctgta ttatatcgga agggatttct atagtactat
      361 taaagtcata gatacctata ttacatggat attttatact attaaactcc tcaagtccat
      421 ttatatttct tataaccttt tcttcaaaca atcgaaagac atccggtttg aagtctttaa
      481 ttttctcttc cttcatccta aaccgcttga attctccatt cctcgtaaac gatacctctc
      541 taacagtctc ggaaagagga actttaaaga aatcagcgaa atccaaagcc acacattcat
      601 taattacttg ataaatataa gaaaggcgca aaaggctatc tctggaatac caataagtat
      661 aattagaaat attatcgaag ttcttattct tgaccttatc ttcagaatac tcaaagaaca
      721 agacttgcat cattgaaaaa gtatctctga tacaagataa atcataatgg gttgttttta
      781 catggctcat caatctagcc aatggattaa ggtctgttcc tatcgcgttt atacctttta
      841 tagaagcctc aactaacgat gtaccgcttc ccatatatgg atcaaaaagt agctcaactc
      901 catcctctgg cctatattcc tctattagag ctcttgctac ttggggaatc atcatcgcag
      961 gatacgcatg atagcaatga gtaaattctt tggtatcggc atccttaaag ctccacctat
     1021 tatcaatcgt tcttttgtac ataccttcct tacttaatat tatgtgagtg caaatatact
     1081 caattgctca catattgtga gcacataagc atatataaaa ctatattttt gggcaaaaat
     1141 aacaataatg attagaaaga ccgagtatca acttgaaatc atccttaaga taaaggagct
     1201 aagagaggcc aacaatgtta gccaaaaaga gttgtcgaat ctcctcgaag tggctccggg
     1261 cttaatcggg agtatagaaa gccctaaatt tccacataag tacaccctta gtcagatcta
     1321 taaaatatgc cactatttca acattaccat agaacagcta ttcatatcag aggaagattt
     1381 ttccaaagat agagatatta ttgacttact catatttaat ataatacgtt atggagaata
     1441 aggattttat tatttcaaag ttcaaagagg ttaaatcctt ggaatatgtt ccaagcaata
     1501 gagccaacaa taccgggatt ggaaaaacat ttgaagatta catcggagtt gtcgagaaca
     1561 atttagacga gcccgattta gctggattcg aaataaaatc tcatcgcggc gcttcatgct
     1621 cttacgttac cctattcact aaaagcccct catttcccaa acgtgcgaat gcttatttaa
     1681 aagataaatt tggaacacct tatgaagatg caccatctat aaatagcttg catacgtcta
     1741 tgtttgcaaa tagctataac acatatatga agaaatattc ttttaaactc ctaaacaacc
     1801 ctgtcgccaa gacaatatta ataggagtat ttgacttaaa tacaaaagag ctgttagatt
     1861 gtagcgtagg ttacacctat caagacattc aaaaagcact aacaaagaag ctaaagaact
     1921 tattatatgt aactgcccaa acgaaaaaag aaggaggtaa ggaactcttc tacttcaata
     1981 aagccgatat atatacagag ccatcatttg agcgttttat atcactctta accgatggga
     2041 agataatgta tgatataaga atcgggagct ataaatctgg ccctaaatat ggtatgccgc
     2101 acgatcatgg gagtggattc agaatattag aggctaatat cagactatta tattctgatc
     2161 acgaaaccat agaataaaac aagctacgct tcatttgttg gcttctgtat caagaccgga
     2221 gataaatacc atagggtttc aacgataata ggctcaatat cccaaccgga tattatccac
     2281 ccaaaaggta tttcccggag accctatgta tgagcctccg tgactggaac agaactctaa
     2341 aatcatatgg gttacctcat cgtcctccgt tccccagccg atttcttgga tgggcacatt
     2401 cttgcctttg ctgttcaagc tataacgggc ggactcaccg agttgaaacc ccatatattc
     2461 ttcataatcg ctacgtttcg tgatatcgcc gtataagatc gtgaaactgg catcgtttac
     2521 ccaatccgta ttttcatcca tccggattac cagcgtaccg atacgcttag catatatatt
     2581 cccgtcctta tcttcccaac gcttctgaag aaagagattc accaaaggca tgtcaatgcc
     2641 atctacctcc gatctcttgc taaaaccact caatttaata cgattgggat caccggagag
     2701 tttcacttta taatcgaata acaaggacgt aggtttttgg tgaaacggga taccgcaaac
     2761 gatctgtccc cacgtctccg aagaattctt cgccggttcc agaaaatggc cgagatagag
     2821 gcatccaccg accagcacct tcacgttcat gatacccatc gccgagatcg attctatacc
     2881 cgtttccagc cgtgcgcaat acccctcatc ccgtctttcg gggtagacac tgacgctagc
     2941 tttcgtaatc ccgctcaccc ttgccatcac gttagaactg ccccaaggcg aagctttcga
     3001 ctcaaaaggt ctatttccga taatcgtatc cgtagggcca acacagtaaa gtgtcttcgt
     3061 ctccttcccg ataatagccg attccgtgat cttacgtacc acccactgat ccagatcgcc
     3121 ataacggatc gcttccgtct ttcgctgggc atatagcgcc atactcatcc ccaaaaagac
     3181 aaataaatag cctaaccgat tatttactac cataagttac cctcctatcc aaatcctttt
     3241 ttatttttgc agcgaaatta attagaatcg ataacacaag gcaagtccgt ataaagaatt
     3301 tattcggatt atccatgata aataacaaac gacgtgaata aacccatggc agaaaagccc
     3361 cggacaccct ccatcgcaat ctctttacta cccgtagtga cattagtcat catgctggcc
     3421 gtagccatct atattttccg gggcgattcc cttggaggag ccagccaaat cgtattattg
     3481 atagccacct cgatctgctc tttgatcgcc gtctttcatt gcaagatcaa gtgggaagat
     3541 atcgaggggc aaatcgcccg taacatctac gggatcgcac cgtctgtcat catcctttta
     3601 ttgatcggaa ccctatcggg cagttggatg gtaagcggga tcgtgccgtc cttgatctat
     3661 tatgggttgc aagtcatgca aacggatttc ttcctcgtgg cctgttgcct gctatgcagt
     3721 atcgtatcgg tcatgacggg tagctcgtgg actaccatcg ccaccatcgg gatcgccttg
     3781 atcgggattg gcgaagcgca aggcttcagt acggggtggg tagcgggagc gattatatcg
     3841 ggcgcttatt tcggggataa gatgtcgccg ttatcagaca ctacggtatt ggcggcctcc
     3901 gtaacggaca cgcccctttt cacgcatatc cggtatatgc tttatacgac cgttccctct
     3961 atgatcgtca cactgatcgt attcagcatc gccggattct cgagggagac agcggacgca
     4021 tcccagatag ccgctttctc cgaagcctta aaaggctcgt tccatatcac gccttggctt
     4081 atgatcgtac cgatcgttac cggaatcatg atcgccaaga agacaccttc gatcgtggtg
     4141 cttttcgcct cctccatact cgccggaata ttcgccttga tcttccagcc aaacgcctta
     4201 ttggagattt ccgggatcac agatagcggg attatcgcct atatcaaagg tctgctgatg
     4261 actttctatg acagcacgca gatacagacc ggcaacgagg ccctgaactc tctagtctct
     4321 acccggggaa tggccgggat gatgaacacg atttggctga tcatttgcgc catgtgtttc
     4381 ggcggggcca tgtccgctag cggcatgctg gaaagcatca cacgtatctt cttgcatttc
     4441 atgcgaggcc gtaccagcat ggtcgcctct accgtcgtgt ccggattatc cttgaacatc
     4501 tgcacggcgg accagttcat cgccatcatc ctgaacagcg aaatgtttaa agaagtatat
     4561 aagcaacgtg gattcgagag ccgcctgctt agccggacaa cggaagactc agtcaccgtc
     4621 acctccgtgc tgatcccgtg gacgacttgc ggcatgacac aatctacaat ccttggcgta
     4681 tctacttgga cttatttccc ttattgcgtc tttaatatcg tcagcccgtt tatgagcatt
     4741 cttatagcgg caaccggtta taagatcgtc caaaagactg tgaaataagn nnnnnnnnnn
     4801 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4861 nnnnnnnnnn nnnnnnnnnn nnnnnnnnng tattttcgca ccatcattat ttaagcgact
     4921 gaatgaacaa tggaaaatca tcttaagaag atgccctccc ctctactttc actagtgcct
     4981 atcctcgtgc tggtagctct tttgtttgta accatacgca cttttggcag cgacgcgttg
     5041 agcggcggaa gccaagtcgt attacttacc accacggcgg tcgcctccct tttggccatg
     5101 atcttctgca aagtcaaatg gcgtgatata gaagaggcga tatgtaaaaa catattggga
     5161 gtggccacgg ctataattat cctattgttg attggcgcct tatccggtag ctggatgatc
     5221 agcggtatcg tcccgacctt gatttattac gggatgcaaa tcatccatcc gagtttcttc
     5281 cttgcctctt gttgcgtgat ctgcgctgtc gtatccgtta tgaccggtag ctcgtggact
     5341 accatcgcca cgatcggtat cgccttgatg ggtatcggtg aggcacaggg cttcgctacg
     5401 gggtgggtag ccggggcgat catctcgggc gcttatttcg gggataagat ctcaccgctt
     5461 tcggacacga cggtattagc ctcttccgta acgcataccc ctttgttctc ccatatccgg
     5521 tatatgatgc ttacgacaat accgtctatg gtgatcacgt tgattatctt taccatagcg
     5581 ggttttacgc atacctcgaa cgcatccggg caaatagccg agttcgccgc ctcgttgaac
     5641 gaaagtttta atatctcact ctggctactg atcgtaccgg tggtaacggg tatattaatc
     5701 gccaagaaag taccgtcttt gatcaccttg tttatctcga cagcgatggc gggggggctc
     5761 gagatctttt tccagcctca tttattgcaa gaggtagcgg gagcgtcggt agcggatgcc
     5821 tcctccctgt ttaagggatt attcatgaca ttctacggga gtacccaaat cgatacgggc
     5881 aacgaggcct tgaacagctt ggtcgccacc cggggtatgg cgggtatgat gaatacgatc
     5941 tggctgatca tctgcgccat gtgcttcggt ggttccatga cggccagcgg tatgctggaa
     6001 agccttacgt ccgtattcct gcgctttatg aaacggaggg tcggcatggt ggcgtctacc
     6061 gtattctctg gtttattctt gaatatcgtt acggccgatc aatacatatc tattatcctt
     6121 accggaaata tgttcaagga tatctacaag aaaaaaggat atgagagtcg cctgttaagc
     6181 cgtacgacgg aagattccgt aaccgtaacg tccgtgctgg taccgtggaa cacctgcggc
     6241 atgacgcaag ccacgatatt aggcgtagcg accctgacgt atcttcctta ttgcttcttt
     6301 aacctgatca gtccgttgat gagtattacg atggccgcca ttggcttcaa aataaagcaa
     6361 caccatgaag aagatcagag tatcattgtt aactaaagtc gttatcgcta tcgccgccgg
     6421 cgtattgttc ggccagtttt taccgggagg aatcgcacgt atctttgtaa ccttcaattc
     6481 attgttcggc aacttcctat cgttctccat ccctctaatc atattggggc tggtgactcc
     6541 cgctatcgga gatctgggta aaggagccgg aaagctattg ttgataaccg ccttgatcgc
     6601 ttacggttca acagtcttct cgggtttctt cacgttcctg agcggatcgg ctatattccc
     6661 gcacatacta ccgaccaaca cggaattgac ggcaatggag aatccggaag atttcatgct
     6721 gacaccttac ttcgtggtaa atatgccgcc tttaatggat gtcatgacag ccttgctgct
     6781 atcctttacg attggcctag ggctttctaa tatagcggga accaccctgc gtgactcttt
     6841 cacggatttc aaggaaatta tcattaagct aatcgaggtg gttatcatcc cgttattacc
     6901 gctccatatt ttcggtatct tcctgaacat gaccgtgagc ggacaagtca tgagtattat
     6961 cacgatgttc ctcaaggtta tcatagtcat ctttgtctta catgtattat tgttattgat
     7021 ccaattcacg atagccggag ccatagccgg gaaaaatccg ctccgcctct tgaagaatat
     7081 gttaccggcc tacgctacgg ctctggggac ccaatcctcc gccgccacga ttcccgtgac
     7141 actggcgcag gctgtcaaga atggcgtacg ggagaatata gcgatcttta ccgttccgct
     7201 ttgcgccacg atccatctgg caggtagcac catgaaaatc gtagcttgcg ctatggctat
     7261 catgatcatg gcgggagaac cggttacctt ctccaatttc agcggattta tcatgatgct
     7321 gggaattacg atggtagcgg ctccgggggt tccgggaggg gctattatgg ccgctttggg
     7381 tatcttgcaa agtatgctag gattcaatga gacactgcaa gcgttaatga tcgcccttta
     7441 tattgccatg gatagttttg gcaccgcttg caacgtgacg ggagatggcg ctatcgctgt
     7501 cgtggtggat aaaatagccg ggaaaaacac cccatagtta cctagagtag caggaagcca
     7561 taagcgcctc caaggtatcg acctcttttt cccgcatcat cgtaagggcg atatgggcac
     7621 aggcgtaagc gtcggccatg gcgttatgat gttgggtaag gtcgtaaccg cagtgggcgg
     7681 ctactgtctg caactgatga tttaccagaa atgggtacat cttccgggat agacggcaag
     7741 tgcaatagaa gggatatttc ggataggcta agtcatatac ctcgtgggcg gctttcaggc
     7801 atccctcatc aaacggactg ttatgggcaa caagggggag atcctttagt ttcggggcga
     7861 tgctttccca agcctcctcg aaacataacg catcattcgt atcctcaacg ctcaacccat
     7921 gtatagccgt agtccaacgg gtatagaaat taggggtagg acgtaccaag gtataaatgc
     7981 tatctactac ccagtcatcc tccaatatgg cgatacctat actgcaaata ctgctccgct
     8041 ttccattagc ggtctcaaag tcaatggctg cgaatcgttc catagataga ttactagttt
     8101 ttaatccgtt tactatttat ttgtagagac gaggcgtgcc ccatctctac aaataacctc
     8161 tcattattta tggctccagt cccttggtgc ggggacaggg gctagcggtt tgcgttcttt
     8221 taattgtttc atgacttcct cgatagcacg gtctaattgt tgatcctcac cgttccattc
     8281 cttgatgggg tcgttatcga tcaagatatc cggatccaca ccgtggttct cgataatcca
     8341 gttacccgtc ttcggatcat agctcgtgaa gaaaggcaca cggatatccg taccgtccat
     8401 ataaggaagc gggccgctaa taccgatgat accgccccaa gtacgggttc caatcaattt
     8461 acctaagcca agcgcacgga agccccacgg gaataaatcg ccatcggaag cggaatactt
     8521 attgatcaag caaactttcg ggccaacctg tacggcatcc ggtacggtcc cgatcaaaga
     8581 agaaccccgg cgcattgtca aacgatacgg ctcacgagac agacgttcca gaatcatcgg
     8641 ggagacattt ccaccgccat tcgcacgatc atcgataatc aaaccttctt tatccaattg
     8701 cggatagaaa tagcgggaga actcattcaa gccttccggc cccatatccg ggatatagat
     8761 ataaccgacc ttaccgttcg tcgccttatc taccttcttg atattatctt ggatccaatt
     8821 atagtgatac aaagaatatt cttccgccaa cggactgacc acgatcttac gagcccccgc
     8881 caactgaggc ttgctattca aagacaactc ggtcggaacg ttcgccttcc cgatcaacaa
     8941 cttatacata tcgttcacgc tattcgtagg tactccgtct atagcgacga tatactctcc
     9001 ggccttcgcc tcaacacccg gctctgtcaa tggagaacgt aattccttac tccaagaagc
     9061 ccccggcagg atcttttcca agcggaagaa accactctta tcccgagaaa cctcagcacc
     9121 tagcagaccc atcgataccc gtttaggact ttccacctca ccggggttca cataagcatg
     9181 ccctactccc agctcgccga tcatctcgcc aataatataa ttcaagtcca aacgtgtttt
     9241 cacgtaagga agaagggcgg cgtatttctc cttgatcgcc ttccaatcct tgccatgcat
     9301 attctccaga tagaaaccat cccggaaagc acgccaagcc tcatcgaaga tttgcgccca
     9361 ttccttcgta tagtctaccg tgatcttcat attcgctaga ttaaccggct tacttaaatc
     9421 cgctttaccc ttcggtatat cggttacgaa tagttgatcg tccttaaaga aaacagcttt
     9481 cttgccagcc ggatcaacca tcatagcggc atcgctaacg gtttcctctt tctgtttctt
     9541 caagtcaaac attttcatgc cgcctttcgt gaaataatac acgttcgttc catcggaata
     9601 aagatcgtag taattcgatc ccggcaaggg gagcttaacg attcgatccg tgataccctc
     9661 tatatcaatc tttacgaccg gagtagaagc ctcattcttt gtctcgtcct ttttagaggc
     9721 atccgctttc gctggggtag attcaatggc gacctccgca tccgtttcca taaacgggga
     9781 agcggtatcc ttagacaata acgccagata tacgccaccc atattattat acacatgatt
     9841 ccattccgtt tggctatacg taggattgaa atcacgggcg gaagtgaata ccagatattt
     9901 gccatccgta ctgaataccg gagaataaga ctcgtaccat ttatcggtca cgggatattc
     9961 tttcttaccc gcgatatcgt agacatagac gatcgagaaa ttattatcgg acacacggga
    10021 ataagtcaac caattattat ccggagagaa acttacgttg cgggcttcac ctaacagact
    10081 ttgtgagata gttgttagct gtttgttaga tacgtccaaa agattgatcc gattcttacg
    10141 atccgtatag acaatcttct tggaatccgg actccactgg aaagtacgga tatacgtatc
    10201 gttattcttg gtcaactggg taggctcgcc cccctcggaa tcttggagat acagctcggt
    10261 ctcgccggta gcgtcggaga tataggctat atgttttccg tccggagacc attgagcgtc
    10321 acgttcgtgc gctcccggag tacgggtgat atttttcgta acccctttat ctaccgggat
    10381 attgaatacc tcgccacgag ctgtcaccac catacgctca cctttggggg agaggctggc
    10441 actcgtgata tatttggaac catccttgat ctcgctacgt gcgtagacat tatcggaggc
    10501 aagggtaacg ttcactttct ccggtttctt cgacgccgca tccatcttat agatatagcc
    10561 tccattctcg aaaacgatcg tattcccgaa actactaggg aatttcacgt cgtactcagt
    10621 gaagttcgtc accttacttg tttgtttagt cttcgtattg taaacgaaca agttcatcgt
    10681 gtaatcccga tctgaaagga aatagatctc atcaccaatc cacatcggaa agatatcttg
    10741 cgcctcattg ttcgtgatat tctctacact tttcttctcc ggattataaa cccagatatc
    10801 atcggccata ccacccttat agtatttcca tgtacggaac tcacgcatta cccggttgta
    10861 agccaattgt tttccgtcgg gcgaatagct acaaaagccg ccctcgggca agggaaccac
    10921 ctcggaaagg ccaccttctt tatttaccgt atataactta ccggagaacc catcgctgat
    10981 gcggttgcgg taaacaatac cattgccgtc cggtgtccaa gtcatcacaa tattattcgg
    11041 gcccatgcga tcgcccagat catcacggct attcgtagcc gtgtaagtga tacgcaatgg
    11101 ctcaccgcca gaagagggca tcgtgtacac ttccgtgtta ccgtcgtact gtcccgtaaa
    11161 agcgatcgtc ttaccatccg gggagaaacg gggaaacatc tcatacccca catacgatgt
    11221 caatcgctgt gcctcaccac ctgtagccgg gaccttatat aaatcgccag catacgagaa
    11281 tacaatctct gaaccatttg tagccggaaa gcgcattaat ctcgcctcat ccgccgccat
    11341 caacaacgta gggatagcga cagccgccaa tgctgttaaa atcattcttt tcctcataac
    11401 caatcttatc ttttaatcat atctgttcta tccgttttta gttggcccaa tagcgggtag
    11461 gacctcaaat gtacataaaa agatccaaaa tccaagtcaa gtcccttata tatccgatcc
    11521 tagaaaaagt tttagaatct ctaatttatt actacctttg cgccagaaat caaacaatga
    11581 tacaaataag atgaacaaga agcttctgaa caactcaaaa agatggtata cccgagcttt
    11641 ctcgggtaac acgatcgtgc atgttcattg gttcagcggt tttgtctaaa tccattcata
    11701 ctcttcttga gaggacttct ttttatagtt ctcttctaca cctacatcta ggtattaatt
    11761 gcactcaagt ttaacttctg cggaaaagag ggagtattcg tatgcttcgt ttccggggaa
    11821 aggatgtctt gcgcatctca aaatacaata tgcttatgtt tatcattcta ggtctattag
    11881 gtctggggat aagcgtcggt tatttatgcc gacacgtccc cgctttcaag ggattggaac
    11941 attccatctc ttatacgatt ttcgcgatgt tgttcatatt tggtattacc ataggagcca
    12001 accaatcttt gctgaataat attggtgagt ttggaataca agctgccata ctagctattt
    12061 gcggagtatt gggaagtctg gtagcatctt ttatcgctta taaattattt atcaagaaag
    12121 gaggtctcaa tgaaaaataa cctaatcgtt atcttatgtt tcacagcggg aatcttttgc
    12181 ggaaccttcg ccaacacgac tatctccacg tattgcgaaa aactaccgca attcttgcta
    12241 tacgccctcg ttatccaagt aggattgaat ctgggagcaa acgccgaatt aggaaagatg
    12301 gtaaaggata tccggttttc cagtttgtta ctgccgttct ttacgatcat cggcacgtta
    12361 gtattctctg cggcggcgag tttgttattg acctcgtgga atatatatga ttgtatggct
    12421 gtaggaagcg gattcgctta ttattcctta tcctccttgc ttatcgtaca actgaaagag
    12481 gcgtcggcag ggatagaaat cgcttcgcaa ctcggggcta tcgcgttatt ggctaatatc
    12541 atccgggaaa tgttagcttt attcggggca ccgttgtatg cctctttctt tggtaaattc
    12601 gctccggtat ccgtggcggg aatcaattct atggatgttt gtcttcccgt tatcagccgg
    12661 tattccggaa agaatatcgt acctgtggct attattcacg ggattatcct cgagatcagc
    12721 gtgccgttgc ttatctcgct cttttgcaag tagaagcagg atttatcctc aacacccgct
    12781 ataaacacaa aagaggatgc gtacattata tcgacgcatc ctcttgttcc tttatccgta
    12841 cttcctcctc acggaggtac ttacggacct cttaatttat tactttagta ttaatattaa
    12901 tccaactccc gcctgttcat ccgtcacgga ttacttggat cgatacccgc acgggaattg
    12961 tatgattatc ttattttgtt aaattcttat ttaacgatag ccttaacagc ttcctcacca
    13021 tcaacagcca ctgctacgat accggcagga acagagattg tagcgttatc ggaagtaaga
    13081 acggtctcag cgattacctt acccaagata ttcgtgataa ctacagactt accagctgcg
    13141 ccttgaacgg ttacggtacc gttaccggct actacagaga taccttctac agcatcgatt
    13201 gtttcgttat ctgttgcgat atcatcacct tgctccacat taaagatcaa agcatcgtca
    13261 ccacctgtat tcatctcatc gaaattagaa gaacgatcat cagacagaac taaacaacca
    13321 ttctgcattc tcaaccaagc cgcatatgta ggagcgatgt cacccatagc agaattattg
    13381 taaccaggaa catgtttact cttcatagac tcgaacaaga atgctctatc agcttctacc
    13441 tcattagcgg caacttcctt gtttacgaaa cgcatagacc aagtcacata cttatggtta
    13501 tcaccagata agatatattt gtgtgaaaca aattcatctt cagatactcc agccttctta
    13561 gccgcagtcc aagcatcctc ctcagccttg ttcaaatcag cgaagttgat cttctcgttc
    13621 ggtaagttct tgaactcatc tctcaagata tacaaagtat cagctacacg gatagcttcc
    13681 acgaaacctg cacgatcata tttcttccac atgtagtcag catcttgctc cccatttgat
    13741 aatgttgacc aaccatattt attagcgaaa tcatggaaat tgatcaaata tttacctctt
    13801 tcaaagcccg gaacagccgg ttttgcgtga acgcaatgcc atttatctgt cggtttacct
    13861 tctgcggtaa agtgatggtc atcttccgta caaggtacgc cttcaactcc ttcgaaatcg
    13921 ttacgatcaa tagagatcaa atattgaggc ttgatattac cagaaccacg gtttacccat
    13981 gcggtatcaa cgatgaatga caaaccatcc tcagtcttat ccggagtata aatacctaag
    14041 aagtcaatac cttctttcat gaagttctta ttattctcaa cctgcaagta ttctttacgg
    14101 tatttctcga taaaacgtaa agtatcggcc ttgtcacctt cattaccttc aagttcaaga
    14161 gaactgaaac gacggtaaag cggagtgttg tccggttcga tagcgaaagc agaagtacga
    14221 gtctcgccta atacttgatt cttcaatgta gcggcaccgt cataatcgga tactccagct
    14281 ttctgataac ctaatacata ttttgtagca ttagaataat tatcatatgc agcattaaca
    14341 atcgcataat agtgctttcc actgatatag ttgttttctt tgaagaatgc ataataagtc
    14401 gtataagatt gctgatgacc agtagcacta gaacctacat taaacttatc ttccttatta
    14461 actttccatt cattaagttc acctttacca tctttataag aaacctcata agcagttctc
    14521 actagagtct tcaagccttt aatacgattc ttagccacat catcgctaac cttataaccg
    14581 taagggatat ctacagtcgc aaatatcttt gagttattat tccaacgctc agtcaatgta
    14641 tcaattacga aagcatcttt tccatccaac acagtcaacg tagagtctgt agatttagcg
    14701 atgtatttat ccgtagcata aggatgccaa tagttaaacg tatatttgtt aaccaacaaa
    14761 gaatctttct ccaactttct gtaacctaaa tacggatcag aaatagaagc tgccggaact
    14821 ttctcgaaga acaaagaatc tataccgaca gagccatact ccgctgtaag tttatctcca
    14881 tatacaaaca tataagaacc accctctgcc tttcttaact gaacagtaga ataaacagca
    14941 gtcttatatg actccatctg gccatcacca tcaaaatccg catttataac tttatctgcg
    15001 aattcacggt tagagatagt aaccggagac acagccttca ctttatcatt acttgtattt
    15061 ttcttcaata caacccattg ataagctggc atatgagcaa cactctgctc atcctcattc
    15121 acggttgtcc aacggatagt accattctca tagataggag aagctaaata ctgtccttgt
    15181 ttattcttga tgaaataaac accatcatca acggaagtct tggaagaacc cttttcctca
    15241 catccgctaa gacccaaaga aatatgagtg ttctggtcct ccggatcaac tgtcaaaata
    15301 caagtttcat ctttaatcaa gtcttgcaaa gagacacgcc agaactcatg ctcgttaact
    15361 ggagtagccg taacgtgcgt attccaatac ttgccatcat tattccaagt aacttttttt
    15421 acatagatgt ataagctatc gccactcgga gaatagatga atttgaactg atgttgagca
    15481 cgtaattcag agctaataga actgtaagca tcagctttat cctttgcttt ctctgtccaa
    15541 ccgtaagcta agaactttgt acctgtctca ttcgtataag ccgtatcaac tttcaaataa
    15601 gcgtctttat ccttttgctt gatgaaaagc catttgttat tatctttatc ctctgcgata
    15661 aacttctgct cattgaacgg attctttaag ctagtacctt tcacgtccgg agtgaaagtc
    15721 aattgtactc cagccttgtt atcttgaaga agacccaact tcgtatttac ttgatcttcg
    15781 ctcaatgcga tttgtgctgc gccaaccaaa gcaaagttag tcacatcagc ggcgtttgaa
    15841 gtggcatcta tttgattagc accccacttg gcaaccttaa cagctccggt agtaggatcc
    15901 gctttcaaac caacaattga gtccgttgag aaataagaat acaaaggtct cttttcttcc
    15961 aaatccttgt atgagcgaga gaatgcccaa cctgcgatct caccacctaa aacaggtttc
    16021 caagcaccat tcgtaccatt ctcagtcttc tcatggccag ccattgtcaa atccaacata
    16081 gttccagaca atttattctg gaagtcataa ataggagctt gaccttgatt ataattagag
    16141 acagaaacac accacaatgt agcctctaag ttatttttag cttcgcttgc actataaaca
    16201 cgtagttcat aatcacctgt tccacgattt agctccatcg caagataagc aggagtagtg
    16261 ccatccatga ccttcaactg ataaagacca gaattagctc cctccttcaa accgcctaaa
    16321 cgccattctt gacccaatac agtttccggg tctactcgac ttggtgtagt ctgtgcatta
    16381 acagacataa cacttaacag tgccatacct gccaaaagag tagaaaactt cttgttcata
    16441 aattcaaaat ttaatattaa taatagtgtt aattaaagtc catcccgccg tttagcaccc
    16501 ttgtttttct cgaaaacgac tagtctaaac gatcgtttag actagccgtt tctatctatt
    16561 atataatgta cgcatgtaca ttatatatgg tatccatcca taaccgcata ataaatacaa
    16621 aatacaaaca ttcacatgta atcattgcaa atactacaaa cgtataatcc aaggcttgtc
    16681 aagccataag cttacgagtt gagaagtgat tagttattca cttggagaac tttatgctag
    16741 cggcttagtc tattatttaa tgttatcttt atacgtgaaa agaataagtc aaccatacca
    16801 aatttgatct cttaaaaagt acaataagcc taatatttaa agattgttat ttatatttct
    16861 gataatcagc gtataataag aattgatcaa aatgggagcc gattactatc catagtattt
    16921 tgcactacta ttaatactaa tcgtactttc tataaatagt aaagctgact accatgaatc
    16981 tgctttttaa gaaatataca ataaacagga tgtgcgatac gaaaataaac cttacctttg
    17041 gagcagtaat cacctaaaac catttaacta tggcacaata cgtagacatc atgactgatg
    17101 ctggatttaa ggctgtcttc caagacaagc aagttaccat caagttcctt aacgccgccc
    17161 tagccggcga acgacagatc aaggacatca cctacctcga caaggagatc aagcccgaga
    17221 ttgtcgagaa ccgtaccatc atattcgacc tgctctgcga ggacgtgtcc ggggccaagt
    17281 tcatcctaga gatgcagaat tgtccccagt actatttctt taacagaggt ttttattatc
    17341 tttgtcgcat ggtggcccgg caaggacaaa tcggcaagca atggcaatat cggttgctac
    17401 ccatctacgg agtctatttc ttgaatttca agttgccgga gttcacagac ttccgtacag
    17461 atgttgtcct cgctaacgag aggacgggaa aggtgttcaa tgagatcaag atgaagcaga
    17521 tctacatatc gttcccgtta ttcagtttaa gcaaggagga gtgcaagagc tccttcgaac
    17581 gttggattta tacattgaag aatatgaacc tatttgaaca atctcccttc aaggaggaac
    17641 aggagacctt ccttcgcttg ctggatgtgg cgaacgtcaa ctcactcagc gaaaaagaac
    17701 gtgcgatcta cgaggaaaac ctaaagaatt atcgggattg gtatgcgacc atcgattacg
    17761 cacaaacgga agggattgaa aaaggaatgc aggaaggaat gcagaaaggg atcgagaaag
    17821 gccgtcaaga ggaaaaactc cagatagccc aaaagatgaa ggagcaagga cttgactccg
    17881 aacttatcgc ccaatgctcc ggactttctg ttgaagacat tgagcgacta taacccgaat
    17941 caaccgattc gattcaattc gatccgggcc gcttccttcc actatccgga ggaaacggcc
    18001 cggattactt tcgtacattc acgataccta gaaagcgtaa ttaaaatcca acggaataaa
    18061 gaaactgacg attgttccgc tccccatccc cttctccttg ctttggaccg aataggtgat
    18121 cttctcttta tttctcctat tcaacaatag gatcgtacgg taaaggactt tcgttcccat
    18181 ccccgtaccg ttcgtatgtc ccgcattcgt aaacggacga tacccgggtc cattatcctc
    18241 tatacggata tggatgcctt tcccgtcgcg ctccacgaaa acggataatc gcttctcgcc
    18301 ctcaatcgca cacaagccat gtttcacggc attctctacg ggaatctgga tcagcatggc
    18361 cgggagatag atcgcgtccg tgtcaaggga aggatcgata ttccatgcca aatggaagtc
    18421 cggccccagc gcttgcgttt gcaggttcag atacgtacgc acgaacctca gctcctcccg
    18481 cagcgtaata ctgagctttt ccgagatctc caagctactc cgcaacaact ccaccagccc
    18541 ggaaagttgc gtgcggcgga ggcttccctc ctcttccgtg ctgatttccc ggttcaaaac
    18601 gttgaatata aaatgagggg atacacggtt gcggatactc tccatcttca gcttcgtcac
    18661 ctgatcgata tggcttaacc actgggcatg ccgtttacgt ttcataaagt aataagccat
    18721 gccgctgacg atcgacaaga tcgcaaaaag caagatccaa acccaacggc tcatttccaa
    18781 gtattccatc cggccggcct gttgtttaat aatagcctcc cgcttgagca aagtcgtatc
    18841 ttgcctataa cgcatatcga tctcggcgac acgcatctgg gttcgttcgc tacgaatatt
    18901 gttctcaatg acgctattct tcgtttgata ctcataagca cgcctaaaat cgcccgtggt
    18961 agcgaagtaa ttctgcaagt tcttattacg gatcactacc atcttgggat ctatgcctac
    19021 cgtatccgtg taactcctca acaattgata agccagcccg gagttcccct cttttaaggc
    19081 tagcgaagcc ttcagggttg tcaaatggta caaggctgtc ttattattat aggtatggaa
    19141 gtacctaaac cctttttcca gataaaaacg agcggaatcc aactgatcca tacatagata
    19201 gatctcccct aaattgatct cgcatacgtt ggtatagaaa tccatatgag taggacgtac
    19261 cacctcacgg gctttcaaga accaaggaag cgcctccgcg tattcttcct tgtaataata
    19321 gtaatttccc cggctattgc aaaaggtgaa tttctcgctc aagttacgag aatccagttc
    19381 tttctccgcc aaacggtaaa agtgatcgga taagtcaaag tccctcaatt ccatatacgt
    19441 ctcgcccaaa ccaaaataaa taggaaagga catccgatcc ataataccca atgaatcact
    19501 cacgaaaaga gcttggcgaa agtagcgggc tcgctgatcg taagctcctt tccgggcata
    19561 tatatccgct atattgatat aaatatccgg gattttatgc tccatctcac tctgccggat
    19621 ctcttgatac gcctcggaat agcaaaggag ggccgaatcc gttttatcca aaaatgaata
    19681 ataattgcca accgtatttt tcagcgtccc taagagtcca tgtatcttgg gagacatcgg
    19741 tacacggtcg caataatcta taattgaccg atgtaaaaca aacccggaat catatacact
    19801 attagcaaaa taaatctggc ttttagccgc aagcaattta taatatttat cgctatcttt
    19861 agttagactt aaagcttcat ccaatgcgga atgagcatat cgaggattcc ggtaaatcga
    19921 atccatagcc atatgttcca aagaatcaat ccgcaggtta tcagaaaaag caaatgtttt
    19981 ttccggtagc tttccacaag aaaacagaaa cacaaaatga aatagcaata ataaaatgga
    20041 cataaaagtc atacacactc tatatttcgt catcatcttg gcggttttaa agttcatatg
    20101 caaaaatatt taaaaattta atctacgcaa ttatttctcc taataaatat cgaaaatcga
    20161 ttacatttgt aaatctaaaa tagagtacac atgaaaaact tgatgattcc tgcgctggcg
    20221 ttatttttat cggcggcggc gcaagcagac gacagtccgt tatggatgcg ttactgtgcg
    20281 atctccccgg acgggcagac gatcgcgttt tcttaccaag gggatatcta cacggtccct
    20341 tcttccggag ggaaagcccg gcagttgaca acacatccgg ctcatgacac ccgtccggtc
    20401 tggtcgcccg acggacaaaa aatagccttt gcctccaacc gtagcggtaa cttcgatgta
    20461 ttcctcatga ataaggaggg aggggaaccc aagcggctca ccacccactc cacaaacgaa
    20521 tatcccacga cctttaagga taacggacac atcttgtatc tggccaacat attgcaagat
    20581 gccaaggata tccaattccc cggcacccgc tttatgcaag tctatgagat aagcacggac
    20641 ggaggaaggc cggatttata ttcttcgtta tacatggaga atatagccct cagcaaggat
    20701 ggcagtaagc tattatacaa tgactataaa ggttacgagg acccttggcg caagcatcat
    20761 caatcttcta tcacccgtga tatatggtta tgtacgcttg gaaaagaccg ctctttccgg
    20821 aaagtaacca cttttggcgg tgaggatcgt aatcctgtat gggccgcgga tggggcgtct
    20881 ttctattacc taagcgagga gaaaggaagc tttaacatct tcaagaagga tttggcaggc
    20941 aacagcgaga aacaaatcac gacgcatacc acccaccccg tgcgtttcct tacctccgat
    21001 aattccggga ctctatgcta tagttacgac ggcgagatct ataccgttaa ggaaggccag
    21061 aaacctgcca aggtgaatat ccagatcgtc gcggataaga tcgagaacga cgtaatccat
    21121 cgtcttctga ccgatggagc tacggatatc gccgtctccc cgaatggaaa agaggtagcg
    21181 tttatcactc gtggcgatgt ttacgtaact tctattgaat acgagacgac tcgtcaaatc
    21241 acgaacacgc cgcaacaaga gcgcaatata gatttcagcc ccgacggacg ttcattggta
    21301 tattccgccg aacgggaagg aacatgggga atctacgaaa gtaaacttac acgtgacgaa
    21361 gataagcaat tcacgtacgc cccagaattg aaagaggagc ctcttgtcgt ctccggacaa
    21421 acctcgttcc aacccttata ctctccggat ggtaacgagg tggctttcct tgagaaccgc
    21481 accaccttac gtgttatcaa ccgaaagacc aagcaggtcc gcaccgtatt ggacgggaaa
    21541 tacctctatt cgtatagcga tggagaccag catttccaat ggtcgccaga cagcaagtgg
    21601 tttttggtag attacatctc cgtcggagga tggaacaata cggatatcgc cctcgtgaaa
    21661 gcggacggta gcggcgaggt aacgaacctg acggaaagcg gttattcgga tggcgacgcg
    21721 aaatgggtat tagacggtaa ggccatgatc tggtcctccg accgtgccgg tttccgcagc
    21781 cacggtagct ggggtgctga gcgggatgtg tacatcatgt tcttcgacgg tgaggcttac
    21841 gataaattcc gcctcagtaa agaagaactg gccttggtag aagcggatga aaacaaagat
    21901 aaggacgagg ataagacatc cgataaagat tccgataaga aaaaagagga taaggataag
    21961 cctgtagccc ccttgaagtt tgatttggag aaccgcaagg accggattat tcgcctgacc
    22021 gctaattcat cctcattggg agacgccgta ctcgccccga aaggagataa actatattat
    22081 tgcgccgctt tcgagaaagg ctttgattta tgggaacacg acttgaagga aaagtccact
    22141 aaattactgc tcaagaatgt cggtcgaggc actctattcg ccgataagaa agtagagaac
    22201 ctctatctta ccgccggcgg caaactgaaa aagatagagt tgaaggatag caaggaaaaa
    22261 ccgatcgctt tcaaggccga gttcgcttat cgtccggcag aggagcgtgc ttatatcttc
    22321 catcacgctt ggcgtcaagt cttggataag ttctatgatc cgacactccg gggcatggat
    22381 tggaaagggt atgagaccgc ttacgcccgt ttccttccgc atatcaacaa caattttgat
    22441 ttccaagaga tgctttccga gctattgggc gagttgaacg gctcccatac gggcgctcgt
    22501 tacaatccgg gactaaccgg gccggaaacc gccagcttag gcgctttctt cgataacgca
    22561 tacacgggcg acggattgaa gatcgaggaa atcatcgcca agggcccgct gacattggcc
    22621 gacagccaga taaagaaagg ctgtatcatc gagaagatag acggaacacc gataaagaaa
    22681 gacgccgatt attatccact gctaagcggt aaagtcggta agaaagtaat gctttctgtc
    22741 tatgatccta ccagcaaaca gcgtttcgag gaacaggtaa aagcgatcag taacggagag
    22801 caatcgaacc tcctttataa aagatggatc gagaattgcc aagaaaccgt agataaatta
    22861 tcgaacgggc aaatcggata tgtacatgta agaggtatga acagcgagag tttccgcgag
    22921 gtctattccg ccttattagg ccgttgccgg aataagaaag ccgtgatcgt ggatacccgc
    22981 cataacggag gtggctggtt gcatgatgat ctggctacct tattgagcgg caaggagtat
    23041 cagcgcttcg agcctcgcgg acaatacatc ggtagcgatc cttacaataa gtggaccaaa
    23101 ccgtcctgtg tcttgatgtg cgaggataat tattcgaacg ctcatggttt cccttgggtt
    23161 tataagacct taggcatcgg caagctgatc ggcgccccgg ttccgggaac catgacagcc
    23221 gtatggtggg aaacgcaaat cgatccgacc ttggtattcg gtatcccgca agtaggcgtg
    23281 aaagatatgc aaggcaatta tctggaaaac caacaattgc aaccggatgt cgaggtgtac
    23341 aatactcccg aggcgcagct ctccggcgag gacacgcaat taaaaagagc ggtagaagtg
    23401 atgctgcaaa ctgtaaaata gcttttctag gcctcggaaa tgacttttca accttgtaaa
    23461 atgccttccg aggcctcgga aatgactttt caaccttgta aaatgctttc cgaggcctag
    23521 aaatgacctt tcaaccttgt aaaatgcctt ccgaggcctc ggaaacgact tttcaacctt
    23581 gcaaaatgct ttccgagacc tcggaaatga cttttcaacc ttgcaaggtg gtttccgaga
    23641 tctcggaagc ctctttcact cacatcgaac agaagaaaga aacgaaaaac ggaaccgtga
    23701 agtccaccaa gatcccgtga aagatggaga caaagaccaa atcctttccg caataacgag
    23761 tgataatcgg caatgtcgta tccatcgtag tagctcctcc tgcgcagatc ggagatagcc
    23821 ttccgaaata tctaacgaac aacggagcgc ccagcaaggc gaatatctca cggataatat
    23881 tagcgatcaa ggcgatcgtt cctaactccg ccgccaattg
//
LOCUS       DBMDTB010000064        23594 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_744_length_23594_cov_10.081854, whole genome shotgun sequence.
ACCESSION   DBMDTB010000064 DBMDTB010000000
VERSION     DBMDTB010000064.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 23594)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 23594)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23594
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_744_length_23594_cov_10.081854"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..938)
                     /locus_tag="ACZPB4_11015"
     CDS             complement(<1..938)
                     /locus_tag="ACZPB4_11015"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HIR1098777.1"
                     /translation="MATKAFQKIYTKITQITKATCSLKATGVGYDELASVDGKLAQVV
                     KIIGDEVTLQVFSGTEGIRTNAEVVFMGKAPSLKVGDQLAGRFFNAYGEPIDGGPIPE
                     GREVEIGGPSVNPVRRKQPSELIATGIAGIDLNNTLVTGQKIPFFADPDQPFNQVMAM
                     VALRAKSDKIILGGMGMTNDDYLFFKNTFSNAGALDRIVSFINTTEDPSVERILIPDM
                     ALSAAEYFAVEKNEKVLVLLTDMTNYADALAIVSNRMDQIPSKDSMPGSLYSDLAKIY
                     EKAVQFPAGGSITIIAVTTLSGGDITHAVPDNTGYIT"
     gene            complement(946..2703)
                     /locus_tag="ACZPB4_11020"
     CDS             complement(946..2703)
                     /locus_tag="ACZPB4_11020"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HIR1098778.1"
                     /translation="MATKGIVKGIVSNLVTVEVDGPVSQNEICYISVGGVKLMSEVIK
                     VIGKNAFVQVFESTRGMRVGDEAEFQGHMLEVTLGPGMLSRNYDGLQNDLDKMEGVFL
                     KRGDYTFALDNDKKWDFKPLAKAGDTVSAGDWLGEVDENFQPHKIMVPFKFEGSYTVK
                     SVVPAGQYTINDTMAVLTDENGTDVNVTMIQKWPVKKAITCYKEKPRPFKLLETGVRT
                     IDTVNPIVEGGTGFIPGPFGTGKTVLQHAISKQAEADIVIIAACGERANEVVEVFTEF
                     PELVDPHTGRKLMERTIIIANTSNMPVAAREASVYTAMTIAEYYRSMGLKVLLMADST
                     SRWAQALREMSNRLEELPGPDAFPMDLSAIVANFYARAGFVRLNNNATGSVTFIGTVS
                     PAGGNLKEPVTENTKKVARCFYALEQERADRKRYPAVNPIESYSKYIEYPEFQEYIAK
                     HISPEWIEKVNEIKTRMLRGKEISEQINILGDDGVPVEYHVTFWKSELIDFVILQQDA
                     FDAIDAVTPLQRQEFMLDRVVNVCRSEFKFDNFLEVMDYFKKMINIFKQMNYSEYESD
                     QFKKFNTELDELLKERIEN"
     gene            complement(2707..3585)
                     /locus_tag="ACZPB4_11025"
     CDS             complement(2707..3585)
                     /locus_tag="ACZPB4_11025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2764 domain-containing protein"
                     /protein_id="HIR1098779.1"
                     /translation="MSKYYYLISGLPNIALDDSKLAYSVCEFRTEIEDMLSSKDKKLI
                     DLFYLKYDNINLLAHAKRPDSDPDQRGRITYDEFNTLYKALKDEEKIPKNDNLPPYFV
                     DFFKLYLAEEAKDTKSEKEYISWEDRLAALYYEYAMKCGNKFVADWFELNLNINNVLT
                     AITCRKYGFDKANYIVGHNEIAENIRTSNARDFGLGDSVEYLPELQRIAEETDLIVRE
                     KKIDLLKWKWLDDNTFFKTFDIESVFAYLLKLEMIERWVTLDKARGEKTFRELVGAMK
                     MGSENALEEFKRNNIK"
     gene            complement(3587..4177)
                     /locus_tag="ACZPB4_11030"
     CDS             complement(3587..4177)
                     /locus_tag="ACZPB4_11030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098780.1"
                     /translation="MDTKIQELTDKIYKEGVEKGNEEAGRIIAEANAQKDTILKDAEA
                     EAKRIVAAAEKQAAELKKNTEAELKLFATQSVEALKSEVTNLITGDIASSNVKAALMD
                     PAYMQKVILELVKSWPANEFLTIQASDSDGLKAYFEANAKGLLEKRYKIEKVSGKKAS
                     FSIIPADGSYKVTFGEDEFIEFFKEFLRPQLVEMLF"
     gene            4374..4880
                     /locus_tag="ACZPB4_11035"
     CDS             4374..4880
                     /locus_tag="ACZPB4_11035"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIR1098781.1"
                     /translation="MFTIRKATIDDRSLIHDLASRIWENTYGKILSKEQLDYMFDMMY
                     APDNILKQMEELHHQYFIILADDMPAGYLSIEKTGENTYNFQKIYSLPEMHGTGIGRF
                     IIEQGINYLKEVHTGPFTIELYVNRYNPAIGFYKHMGLREIGTRDHHIGNGYFMNDYI
                     MGMEVENK"
     gene            complement(4932..5084)
                     /locus_tag="ACZPB4_11040"
     CDS             complement(4932..5084)
                     /locus_tag="ACZPB4_11040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098782.1"
                     /translation="MDKKQEKKIWNSQLAIENPKNDRIAVIYSVKVSSVRILEKPRNP
                     KRGKTR"
     gene            complement(5118..6032)
                     /locus_tag="ACZPB4_11045"
     CDS             complement(5118..6032)
                     /locus_tag="ACZPB4_11045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HIR1098783.1"
                     /translation="MKNKKTEANISMVVSKTFSGLNMNALKYLLPLWMSPLTGASFRC
                     VFAAVAFWVIGWFMKPEVSTTKDKVWLFLLGAIGIYGFMFLYLVGLSKTTPVSSSIFT
                     SLQPIWVFLIMVFFYKEKATWMKILGILIGLSGALVCILTQQSDDLAADAFNGNMLCL
                     ASSVFYAVYLVLSQRILQKVGTMTMLRYTFTGAAFSSLLILPIEGFHAPLFSEPFHWW
                     PFAVLMFVLIFPTVISYLLIPIGLKYLKTTLVAIYGYLILIMATITSLLIGQDRFSWT
                     QTFAIICICAGVYLVEIAEGKEKKTVKV"
     gene            complement(6065..7291)
                     /locus_tag="ACZPB4_11050"
     CDS             complement(6065..7291)
                     /locus_tag="ACZPB4_11050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HIR1098784.1"
                     /translation="MRIQTGRGTIPLITLVGIWSISALNALPGLAVSPILGKLSVIFP
                     HSTELDIQMLSSLPSLLIIPFIILSGKLTEKVNEIRLLQLGLVIFALSGILYLLSNKM
                     WQLIAVSALMGIGSGLIVPLSTGLISRFFIGKYRTKQFGLSSAITNVTLVLATILTGY
                     LAEVNWHLPFAVYLLPLISIVLSVYLKRSMENEPAIVSKSEVKAPVAADPVTVPGKYG
                     VDIKHLVQIMCFYGLATYLVIIVSFNLPFLMKEYKFTSGNSGLMISLFFLAIMVPGFI
                     LNQIVDLFKQKTKFVSLLAIALGMALILISRTEWLIGLGCIFIGFGYGVIQPIAYDKT
                     TRTAIPEKVTLALAFVMAMNYLAILLCPFIIDFFQSILHVKSQQFAFIFNLCIALVAT
                     IWAYVKRDSFLFNDKI"
     gene            7514..8953
                     /locus_tag="ACZPB4_11055"
     CDS             7514..8953
                     /locus_tag="ACZPB4_11055"
                     /EC_number="4.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004351 - glutamate decarboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0006540 - gamma-aminobutyrate shunt
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate decarboxylase"
                     /protein_id="HIR1098785.1"
                     /translation="MKDSNFRNGDAKTAIFGSEVMLTPSPVDKIPDGPTTPEIAYQMV
                     KDETFAQTQPRLNLATFVTTYMDEYATKLMNEAININYIDETEYPRIAVMNAKCINIM
                     ASLWNSPEQEKWKTGALAIGSSEACMLGGVAAWLRWRKKRQAQGKPTDKPNFVISTGF
                     QVVWEKFAQLWQIEMREVPLTLDKTTLDPEEALKMCDENTICIVPIQGVTWTGLNDDV
                     EALDKALDAYNAKTGYDIPIHVDAASGGFILPFLSPETKWDFRLKWVLSISTSGHKFG
                     LVYPGLGWVVWKDKKYLPEEMAFSVNYLGANITQVGLNFSRPAAQILGQYYQFIRLGF
                     EGYKQIQYNSMEITKYIHQEIGKMAPFVNYSNEVVNPLFIWYMKPDYAKNAKWTLYDL
                     QDKLQQSGWMVPAYTLPKKLDNYVVMRVVVRQGFSRDMADMLLGDIKNAVEALEKLEY
                     PTPTRIAQDKNVPVKGKVFTHTAMSNAKK"
     gene            9029..9994
                     /gene="glsA"
                     /locus_tag="ACZPB4_11060"
     CDS             9029..9994
                     /gene="glsA"
                     /locus_tag="ACZPB4_11060"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005796568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HIR1098786.1"
                     /translation="MDKKITIAQIKEVAQQAYDLYKTNTDGKNADYIPYLANINKNLF
                     GISICLLNGQTIEVGDSEYRFGIESVSKVHTAILVLRQYGAKELLEKIGADATGLPFN
                     SIIAILLENDHPSTPLVNAGAITACSMVKPVGDSKQKWDAIVANITDLCGSAPQLIDE
                     LYKSESATNFNNRSIAWLLKNYNRIYDDPDMSLDLYTRQCSLGITAKQLSVAAATVAN
                     LGLNPVTKKQVFDAELSPKITSMISTVGFYEHTGDWLYTSGIPAKTGVGGGVMGVLPG
                     QFGISAFAPPIDQAGNSVKAQLAIKYVMNKLGLNVFNGHRVTIVD"
     gene            complement(10105..11088)
                     /locus_tag="ACZPB4_11065"
     CDS             complement(10105..11088)
                     /locus_tag="ACZPB4_11065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008933 - peptidoglycan lytic
                     transglycosylase activity [Evidence IEA];
                     GO_process: GO:0000270 - peptidoglycan metabolic process
                     [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HIR1098787.1"
                     /translation="MKMRISKNNLASFLCGGVVCLTACISMGSNDVEKVIESRPVVSS
                     MTLSPDVPSSVPFCGKLIDITRYDMREAYDRELSSFTYFHSTTMLLIKRANRYFPVIE
                     PILKANGIPDDFKYLAVIESHLDPRVSSPARAVGMWQLLEGTAREYGLTITPTVDERC
                     HVEKATGAACRYLKAAYKKYGDWAAVAASYNGGMGRISGELVKQDADSSFDLWLVEET
                     TRYIYRIMAIKQIFENPSKYGFVLRARDLYKPIPTVDVAVSQDIQNLSAFAKEHGITY
                     ADLKRFNPWLRDRKLVTGGKTYKLSIPQEKDMYYKTPNTEVYDSAWVVSEN"
     gene            complement(11063..12406)
                     /locus_tag="ACZPB4_11070"
     CDS             complement(11063..12406)
                     /locus_tag="ACZPB4_11070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="T9SS type B sorting domain-containing protein"
                     /protein_id="HIR1098788.1"
                     /translation="MLKKELRKILLSLSFVFVVAVSYAQYVVTGGSGSPMKASQSSGD
                     SAERLEVYLVYGMDNVTISYTSSSSSSHQWYRYKTKRLEAEKVASTQNGTTSTIRNVE
                     EGYGYFVEEGAVSRYVWIVDYSKYTLNISNLHVSDNSDPCSGLVLAGTGTIQPIYYYW
                     PNTGTRRELSRQFDVIYNTLEYNSDKKEYTSKQETAVIEGNLFGKSIPAPWCDTEICV
                     KGDYFARHFGKEVTLCIDEYQAAAVDAHIDTLLIEQEAPNMNTTKSGYCAPATVQFSA
                     IANTPTAALFNWKIYRQGEEDNPVVRFTGEEVDYTFNQSGTFIIKLEVSDQSTTCSTE
                     DEVQIDISESYLMIPNAFSPGTTPGINDEFRVAYKSLVKFKAWIFNRWGLQMYYWTDP
                     AQGWDGKKGGKYVQPGVYFYVIEAEGSDGIKYKEKGDINILRPKTIQDENENIQE"
     gene            12511..14319
                     /locus_tag="ACZPB4_11075"
     CDS             12511..14319
                     /locus_tag="ACZPB4_11075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HIR1098789.1"
                     /translation="MNKISIYALTFFLSLSSVTVYSQKNNKQVIFTNEQGSDIFYHTI
                     ERGQTVYAIATMYGVSVEDIYRLNPESKEGIKAGSTLRIPQKDSAIAPSGKADNYTYH
                     TIQPKETLYSLSIKYSVPATDIIAANPGLSTSTFTIGKNIRIPPTRLETLPTTEKKTV
                     QKEMEYTIQKKETMYRICRKFDISSVELLRLNPELKNGVKAGMVIKIPVASEEVITQN
                     IRQPEEREVNALLSTPKDIKKVNRIQVALLLPFMTNETTQSSATSRFVEYYEGLLLAV
                     DSLRNMGTSIELSVYDTGNGTKKVKEILKEDALSNANLIIGAVQNDQIGLIADFAQKH
                     NIKYVIPFTSKNDDVLSNANVYQVNTPHSYLYSKAAQAGCDLFSDYNIILVNIKDKEE
                     KPEFIKAFKTEMQQRDIPFKEVTYKGDTFATDIEAAMVRDKRNVVLPTSASLDAVNKI
                     KAPLRMLSELKEEEKEPYMVNLFGYPEWQTYTRECLEDFYALNTYIYSNFYADNLSPE
                     VHSFYSDYKNWYSKNLINTFPKYGILGFDTGMYFLGAINKYGSNFENNLDKIHYKSIQ
                     TGFDFHRVNNWGGFINTNLFIVHYKNDYTVTRSEVR"
     gene            14325..15002
                     /locus_tag="ACZPB4_11080"
     CDS             14325..15002
                     /locus_tag="ACZPB4_11080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0015288 - porin activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="porin family protein"
                     /protein_id="HIR1098790.1"
                     /translation="MMTKKIFVAIFLCMASLSICHAQKSTFKQELAVGASFGLNFSSV
                     SFAPKVPTKMKLGFNGGATIRWNTEPNLGIQAELNFTQHGWEEKFEEKPQYKYSRTVN
                     YMELPFLTHIHFGSKRVRVFVNLGPKIGYALSESTESNLNGENPNANRPDEQHTLEVQ
                     KKFDWGLCGGPGIELRTGIGSFLLEGRYYYALGDMFNSRKGDTFSKSSSQIISAKLTY
                     LIPIFSK"
     gene            15607..16236
                     /gene="udk"
                     /locus_tag="ACZPB4_11085"
     CDS             15607..16236
                     /gene="udk"
                     /locus_tag="ACZPB4_11085"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004849 - uridine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HIR1098791.1"
                     /translation="MLIIGIAGGTGSGKTTVVKKIIESLPPGEVVLLPQDSYYKDNSH
                     VPVEKRQYINFDHPDAFDWPLLSEQVTLLKEGKCIEQPTYSYLTCCRLPETIHIEPRD
                     VVIIEGILALCDPQLRDLMDLKVFVDTDSDERLIRVIQRDMIERGRTAEAVMERYTRV
                     LKPMHLQFIEPSKRYADLIIPEGGSNQIAINILKMFIENNLGLPHTDNQ"
     gene            complement(16193..17539)
                     /locus_tag="ACZPB4_11090"
     CDS             complement(16193..17539)
                     /locus_tag="ACZPB4_11090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042242 - cobyrinic acid a,c-diamide
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cobyrinate a,c-diamide synthase"
                     /protein_id="HIR1098792.1"
                     /translation="MRSHLLIGAASSGSGKTTFTLGLLRALRSRSLRVQPFKCGPDYI
                     DTRHHKMAAGCASVNLDGFMMSEGHIKDLYARYTSNADVAVTEGVMGLFDGYDAMRGS
                     SAEISGLLRIPIVLVVNAKSTAYSVAPLLYGFRNFRKDLNVVGAVFNFVASESHYSFL
                     RQACEDAGVEALGYLPKCADVEIPSRHLGLSLDEDFCFEEFADRVACLVEEHVDIDRL
                     LAITALPERQPVPRVKEVMRTVSKANLNIAIARDPAFNFSYEENIHFLSTLGKITYFS
                     PLRDDCLPEADFVYLPGGYPELYLSELSMNSGMRESIHSFVEVGGKLLAECGGMMYLC
                     KEIIGTDGNAYPMAGVLPQSATMENMKLRLGYRTLCYKNDVLRGHEFHYSRIVPMESP
                     LPSVAKAFTAKGGQTDTPLYRYKNVLAGYTHLYWGDPCRNDWFIDYLYGEAPDCSR"
     gene            17860..>18698
                     /locus_tag="ACZPB4_11095"
     CDS             17860..>18698
                     /locus_tag="ACZPB4_11095"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016791 - phosphatase activity [Evidence
                     IEA];
                     GO_process: GO:0006644 - phospholipid metabolic process
                     [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HIR1098793.1"
                     /translation="MTYIGVPLIVSGLIIKNEDDHFQSLRNTYIPNFRYHYDDYLQYL
                     PAVAMLGLKIGGVQGRSSWSRMLVSEAITASIMGATINTVKHTANVTRPDGSNNHSFP
                     SGHTAMAFMAATMLHKEYGTTRSPWYSIGGYTVATATAVSRMLNNKHWLSDVMVGAGI
                     GILSTEVGYFLTDLIFKDKGITHSYLGFETFNYQRNPSFFGIYMGFSLMPTKFNLAPD
                     VRLKASPGSTAGFEGAWFMNRYIGFGGRISATSMPLSLTKPLANPTVPGTTYQVNALK
                     SDPL"
     assembly_gap    18699..18798
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <18799..19287
                     /locus_tag="ACZPB4_11100"
     CDS             <18799..19287
                     /locus_tag="ACZPB4_11100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HIR1098794.1"
                     /translation="ISATSMPLSLTKPLANPTVPGTTYQVNALKSDPLDMIGGYIGSY
                     LSYPVTNRFLLGTKLLIGCNYSPASRISALGVEEGKPETIEKEIVNTNKAFNIGYSTN
                     ASFSYILHPNLNVRVFLDYTFIPSRFVSYIANPKKETDRFEHHKTLQALTLGASVNIM
                     LW"
     gene            complement(19297..20118)
                     /gene="panB"
                     /locus_tag="ACZPB4_11105"
     CDS             complement(19297..20118)
                     /gene="panB"
                     /locus_tag="ACZPB4_11105"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003864 - 3-methyl-2-oxobutanoate
                     hydroxymethyltransferase activity [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HIR1098795.1"
                     /translation="MSVAKVDDNRKVTTHRLIEMKQRGEKISMLTAYDYSMAKLIDQA
                     GMDVILVGDSASNVMAGNVTTLPITLDQMIYHGKSVMKAVNRALVVVDLPFGTYQGNS
                     KEALASAIRVMKETHADCIKLEGGAEVRESIERILCAGIPIMGHLGLTPQSINKFGTY
                     TVRAREEAEANKLIEDAHLLEEIGCFALVLEKIPAELAARVASELTIPVIGIGAGGGV
                     DGQVLVMHDMLGINQGFSPRFLRRYANLGEEITRAVQAYIEDVKSQDFPNEKEQY"
     gene            complement(20162..20608)
                     /locus_tag="ACZPB4_11110"
     CDS             complement(20162..20608)
                     /locus_tag="ACZPB4_11110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HIR1098796.1"
                     /translation="MAKYASFGKRENEKKKQARRVEKQNRKEERKSSGKATSFEDMIA
                     YVDENGMITSVPPELRQKEEINQEDILISTPKKEDVAPVILRGRVDYFNEAKGFGFIR
                     DLSGTEKYFFHVNNVVDDISVNDIVTFDLERGDRGLSAVNVCLENK"
     gene            20854..21432
                     /locus_tag="ACZPB4_11115"
     CDS             20854..21432
                     /locus_tag="ACZPB4_11115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HIR1098797.1"
                     /translation="MKLLFFDLETTGIKYWRNGVHQISGEIVIDGVTKESFNFNVCPH
                     PQCEIEEEALRICNVSKEQIQAYPPMREVYVKFVNMLSKYVDKFDKKDKFFLVGYNNA
                     SFDNHFLKAFFVQNGDNYFYSWFWVNSIDVMVLSTQHLMRKRHEMTDFKQETVARALG
                     IQIDSAKLHDASYDIQLTKEIYNRISSLSFMG"
     gene            21510..22499
                     /locus_tag="ACZPB4_11120"
     CDS             21510..22499
                     /locus_tag="ACZPB4_11120"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_process: GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HIR1098798.1"
                     /translation="MSVKHSIRIFFFIIALVYTGSLTAQEKAYPKNGEGITLFLKRFN
                     RTGGTYQKEFIELNKGKLGKNNTLRMGVKYTLPPLASAPQKKNYQPLFGKSLASYKVT
                     SSDLKGACFYLVSGHGGPDPGAIGKMGSHELHEDEYAYDIMLRLARNLLTRGAKVHII
                     IQDAKDGIRDQQFLNNSKRETCMGSPIPLSQVSRLDQRCAKINSLSRKDKETYKRAIF
                     IHVDSRSRHQRTDVFFYHKPKDQASKRLAKTMKSTFSRKYNRHQPGRGFSGTVDDRNL
                     YVLRHTTPTSVFVELGNIQNQYDQQRIILSNNRQALANWLCEGFVTDYNYYRK"
     gene            22680..23366
                     /locus_tag="ACZPB4_11125"
     CDS             22680..23366
                     /locus_tag="ACZPB4_11125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HIR1098799.1"
                     /translation="MATTRILVVDDEEDLCEILKFNLEIEGYEVDTAYSAEEALKKDL
                     TVYNLLLLDVMMGEISGFKMARILRQDEKTANTPIIFLTAKDTENDMLTGFNLGADDY
                     ISKPFSIRQVIARVKAVLRRTSEKSKEKEIEKLEYETLALDTKRIKATVDGVEVPLTK
                     KEFEILKLLLENKGNVFSREEILSRIWKDEVYVLDRTIDVNITRLRKKIGPYGKNIVT
                     RLGFGYCFEC"
     gene            23382..>23594
                     /locus_tag="ACZPB4_11130"
     CDS             23382..>23594
                     /locus_tag="ACZPB4_11130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HIR1098800.1"
                     /translation="MVKIDGEKRHRIPFSQRLFWSVFFMFLGFTVCFLLFQYQREREF
                     AQEKLNNVLSNYNYQLFRKCQQSTDIN"
BASE COUNT         6962 a         5561 c         4746 g         6225 t
ORIGIN      
        1 gtgatataac ccgtattatc aggtacggca tgcgtgatat caccaccgga taaggtcgtt
       61 acggcgataa tcgtgatgga acctcccgcc gggaattgaa cggctttctc gtaaatcttc
      121 gccaaatccg aatacaagga acccggcata gagtccttag acgggatctg gtccatacgg
      181 tttgatacga tcgccaaggc atcggcgtag ttggtcatat cggtaagcaa taccaagacc
      241 ttctcgttct tctccacggc gaaatactca gcggcgctca acgccatatc cgggatcaag
      301 atacgctcta cggacgggtc ctcggtcgtg ttgataaaac taacgatacg gtctagggca
      361 ccggcgttac taaatgtatt cttaaagaac aggtagtcgt cgttcgtcat acccatacct
      421 cccaagataa tcttatcgga cttcgcacgc aaggctacca tcgccataac ttggttgaaa
      481 ggctggtcgg ggtcggcgaa gaacgggatc ttctgaccgg ttaccaaggt attattcaag
      541 tcgataccgg cgatacccgt agcgattaat tcagagggtt gtttacgacg taccgggttc
      601 acggacggac caccgatctc gacctcacgt ccctcgggga tcggaccgcc atcgataggc
      661 tcgccataag cgttgaagaa acgtccggct aactggtcac ctactttcaa ggaaggggcc
      721 ttccccatga ataccacctc ggcattcgta cggatacctt ccgttccgga gaatacctgc
      781 aacgtcacct cgtcgccgat aatctttacc acctgagcca gctttccgtc tacagaggcc
      841 aactcatcat acccaactcc cgttgctttc agcgaacagg tagcttttgt gatctgggta
      901 atcttcgtat atattttttg aaatgctttt gttgccataa ctcttttaat tttcgattct
      961 ctccttcaaa agttcatcca gttccgtatt aaacttcttg aattggtcac tctcatattc
     1021 cgaatagttc atctgcttaa agatgttgat catcttctta aagtagtcca taacctcaag
     1081 gaagttatca aacttaaact ctgaacggca aacatttacg actctatcca gcatgaattc
     1141 ctgacgttgc aacggagtaa ccgcatcaat ggcatcgaaa gcatcctgtt gcaagatcac
     1201 gaagtcgatc aactcggact tccagaatgt aacgtgatac tcgacaggca caccatcatc
     1261 acccaagata ttgatttgct cggagatctc cttaccacgc aacatacggg tcttgatctc
     1321 gtttactttc tcgatccatt ccggggagat atgtttagcg atgtattcct gaaactccgg
     1381 atactcgata tacttggaat aactctcgat cgggtttacg gccggataac gtttacggtc
     1441 ggctcgctcc tgctccaagg catagaaaca acgggccacc ttcttcgtat tctcggtcac
     1501 cggctccttc aagttaccac cggctggcga taccgtaccg atgaaagtga cggagcctgt
     1561 agcgttgtta ttcaaacgaa cgaatcccgc acgagcgtag aagttcgcca cgatagcgga
     1621 caagtccatc gggaaagcat ccggtccggg caactcctcc aaacggttgg acatctcacg
     1681 caaagcctgt gcccagcggg aagtagagtc ggccatcaac agaaccttca aacccatgct
     1741 gcgataatac tcggcgatgg tcatcgccgt atatacggat gcctcacgag cggctaccgg
     1801 catgttggat gtattggcga taatgatcgt acgttccatc aatttacgtc ccgtatgcgg
     1861 gtctaccaat tccgggaact ccgtaaatac ctctacgacc tcattcgcac gctcaccgca
     1921 ggccgcgata atcactatat ccgcttccgc ttgtttagag atagcgtgct gaagcaccgt
     1981 cttgcccgta ccgaacggac cggggataaa tccggtacca ccctcaacga tcgggttcac
     2041 ggtgtcgatc gtacgaacgc ccgtctccag caatttgaat ggacggggct tttccttata
     2101 acaagtgata gctttcttta ccggccattt ctggatcatc gtcacgttta cgtccgtgcc
     2161 attttcgtcc gtaaggacag ccatcgtatc attgatggta tattgtccgg ctggaaccac
     2221 cgatttcaca gtataagatc cctcgaactt aaaggggacc ataatcttat gaggttggaa
     2281 attctcgtcc acctctccca gccaatcacc ggcgctcacg gtatcgcccg ctttagccag
     2341 aggcttgaaa tcccacttct tatcattgtc caacgcaaac gtataatcgc cacgtttcaa
     2401 gaatacacct tccatcttgt ccaagtcatt ctgcaaaccg tcatagttgc gggacaacat
     2461 acccggaccc agcgtaactt ccaacatatg cccttggaat tcagcctcgt caccgacacg
     2521 cataccacgt gtgctctcaa atacttgtac aaaggcattc ttacctatca ccttgattac
     2581 ttccgacatc agcttcacgc ctccgacaga aatgtaacag atctcattct gagaaaccgg
     2641 accatccacc tctacggtta ctaggttgga tacgattcct tttacaattc ctttcgtagc
     2701 cataatttat tttatattgt ttcttttaaa ttcttccaac gcattctcac tacccatctt
     2761 catggcgcct accaattcac ggaaagtctt ctcgcctctc gccttatcca aggttaccca
     2821 gcgctctatc atctccaatt tcaataaata agcgaataca ctctctatgt cgaacgtctt
     2881 gaagaaggta ttatcgtcca gccatttcca tttcaaaaga tcgattttct tctcacgaac
     2941 gatcagatcg gtctcttcgg cgatgcgttg taactcgggc aaatattcca cggaatcgcc
     3001 caagccgaaa tcacgggcgt tcgacgtacg gatattttcc gctatctcat tatgccccac
     3061 gatataattg gccttatcaa atccatattt acggcaagtg atcgcagtaa gaacattgtt
     3121 gatattcaag ttaagctcga accaatcggc cacgaactta ttcccacatt tcatggcata
     3181 ttcataatat aacgcagcca agcggtcttc ccatgatata tattctttct cacttttggt
     3241 gtccttagcc tcttcggcta gatacagttt aaaaaagtcc acgaaataag gcgggagatt
     3301 atcatttttg ggaatttttt cctcatcctt caacgcttta tataaagtat tgaactcatc
     3361 atacgttatt cttcctcttt gatccggatc ggagtccggt cttttagcgt gagccagcag
     3421 atttatatta tcatatttca aataaaataa atcaatcagc tttttatcct tagaagatag
     3481 catatcctct atttccgtcc ggaactcaca gaccgaatag gctagtttac tatcatccaa
     3541 cgctatgtta ggaagtccgg agattaagta gtaatactta ctcatatcag aacagcattt
     3601 ctactaattg cggacgcaag aactctttaa agaactcgat gaactcgtct tcgccaaacg
     3661 tcactttata agacccatcc gccgggataa tagagaaaga cgctttcttt ccgcttacct
     3721 tctcgatctt ataccttttc tctagcaagc ctttggcatt ggcctcaaaa tacgccttca
     3781 agccatcgga atcagaagct tggatagtca agaactcatt agcgggccag cttttcacaa
     3841 gctcaaggat cactttctgc atataggcgg gatccatcaa cgccgctttc acattcgaac
     3901 tagcgatatc accagtgata aggtttgtca cctcgctctt taatgcctcg acagactggg
     3961 tggcgaacaa tttcaattcg gcttccgtat tcttcttcaa ctcggcagct tgtttctcgg
     4021 cagccgctac gatacgtttc gcttccgctt ccgcatcttt aagaatcgta tccttttgag
     4081 cattggcctc ggcgattata cgccccgctt cttcgttccc cttctctaca ccttccttgt
     4141 agatcttgtc tgttagttcc tgaatctttg tatccatttc ctattatgta tttgaattgt
     4201 atttttcaat agtaaacgcc cacaaagtta ttatttttcg cggattaaca tcaaaataag
     4261 tgtgaaatca agctaaaaaa taacactagt caagtaaaat tctatttaca ttcgtctata
     4321 ttgtattttt gttcgtctat ttgtatcttt gtgagtcaaa atacaaaatt aacatgttta
     4381 cgattagaaa agcgactatt gatgatcgtt ctcttattca tgaccttgcc tcacgcattt
     4441 gggagaacac gtatggaaag atactttcta aagagcaatt ggattatatg ttcgatatga
     4501 tgtatgctcc ggataacatt cttaaacaaa tggaagagtt acatcatcaa tattttatta
     4561 tattggcgga cgatatgccg gcaggctatt tatccataga gaaaacaggt gaaaacacgt
     4621 acaattttca aaagatctat tccctaccgg aaatgcatgg cacaggaatc gggcgtttta
     4681 tcatcgagca aggtattaac tatttgaagg aggtacatac cgggcctttc actatagaat
     4741 tatacgtaaa ccgttacaat cccgccatag gcttctacaa acatatggga ttacgggaaa
     4801 taggcacacg ggaccatcat ataggaaacg gctatttcat gaacgattat atcatgggca
     4861 tggaagtgga gaataaatag acagtcatcc cctattcata tatttatata tagaataggg
     4921 gatgatgatt gtcaacgggt cttccctctt ttcggattac gaggtttctc taggattcgt
     4981 acactactaa cttttacaga gtaaataaca gcgatcctat cattcttcgg attctcaatc
     5041 gcaagttgag agttccagat tttcttttct tgttttttat ccataacgct acaatttaat
     5101 agttcatatt taataagtca aaccttgact gtctttttct cttttccttc cgctatctca
     5161 accagataaa ccccggcgca aatacagata atggcgaacg tctgtgtcca actgaaacgg
     5221 tcttgcccga tcaataggga tgtaatcgtt gccatgatca agatcagata gccataaata
     5281 gccaccaacg tagttttcaa atacttcaat ccgataggaa tcaacagata actaattacc
     5341 gtagggaaaa taagcacaaa catcaatacg gcaaaaggcc accaatgaaa tggctccgag
     5401 aataaaggag catgaaagcc ttctatcggc aaaatcaata gactggagaa agcggcgccc
     5461 gtgaatgtat atcgaagcat cgtcatcgtc cctacttttt gtaagatccg ctggcttaag
     5521 accaaataca cggcataaaa cacggagcta gccaagcata gcatatttcc attaaaagcg
     5581 tccgccgcta aatcgtcgct ttgctgggtc aagatgcaaa ccaaggcccc ggataaacca
     5641 atcaagatac cgagtatttt catccaagta gccttttcct tataaaagaa taccataatc
     5701 aaaaataccc agatcggttg caagctcgtg aaaatagaac tcgagaccgg cgttgtctta
     5761 ctaagcccca ctaaataaag aaacataaaa ccatagatac cgatagcgcc tagtaagaat
     5821 agccacacct tatctttcgt cgtagaaacc tccggtttca taaaccagcc gatcacccaa
     5881 aacgccacgg ccgcaaacac gcatcggaaa gaagcgcccg tcaacgggct catccataag
     5941 ggaagcaagt atttcaaggc gttcatattc aatccactga aagtttttga gaccaccatg
     6001 ctaatattag cttctgtttt cttatttttc actatctatc gttttttagt tttatattcg
     6061 taaatcatat tttatcgttg aaaaggaacg agtctcgttt tacataagcc cagatcgtag
     6121 cgaccagcgc aatacagagg ttaaaaataa acgcgaattg ctggctcttg acatggagta
     6181 tagactggaa gaaatcgata ataaacggac aaagtaatat cgccaaataa ttcatcgcca
     6241 tcacgaaagc taatgccaat gtaactttct caggaatggc cgtacgagtc gttttatcat
     6301 aagcgattgg ctggataaca ccatatccga aaccgataaa aatacatccc aatccaatta
     6361 gccattccgt acgagatatc aaaatcaaag ccatccctaa agcgatcgcc aatagactga
     6421 caaattttgt cttttgctta aataaatcaa cgatctgatt caagataaaa ccgggaacca
     6481 taatagccaa gaaaaacaat gatatcatta atccggaatt accgcttgta aacttatatt
     6541 ccttcattaa aaacggtaag ttaaagctga ctataatcac taaatacgta gccaatccat
     6601 aaaaacacat gatttgtacc agatgcttta tatccacacc atatttaccc ggaaccgtga
     6661 cgggatctgc cgcaacaggg gctttcactt ctgatttcga tacgatcgcc ggctcattct
     6721 ccatactcct tttcaagtat acggaaagta cgatggaaat caagggcaat agataaacgg
     6781 caaacggtaa atgccaattc acctccgcca gatatcccgt taagatcgtg gctaatacca
     6841 acgttacatt tgtaatagca gaacttaaac caaattgctt cgtccgatat ttcccgataa
     6901 agaaacgaga aatcaaaccg gtcgataagg gtacgatcaa gccagatccg attcccatta
     6961 aggcgctcac cgctatcaac tgccacatct tattagagag taagtataga ataccactta
     7021 gggcaaagat caccaagcct aattgcaata gacgtatctc atttactttc tccgttaatt
     7081 tacccgacaa tataataaat ggaattatca ataacgatgg caaagaggaa agcatctgaa
     7141 tatccagttc cgtagaatga ggaaaaatga cggaaagttt ccctaatatc ggagaaaccg
     7201 ctaaacccgg taatgcattt aaagcggaga tagaccatat ccctaccaga gttataaggg
     7261 gaattgtgcc ccggcctgtc tgtattctca taaagattta gttttacgtt tttatctaat
     7321 caaaacaaac attttatgtg aaagttcatc attttcgctc tttccaagag gactggactt
     7381 gtatcgctaa taaaccccaa ataatgtaaa tccaaaaaac attccaatcc ataatctgtt
     7441 ttggcataaa cgctcagtgg aagcagtatt ccattgactc aaatcatttt attaacaaaa
     7501 aaactaaaga aaaatgaaag actcaaattt cagaaatggc gatgccaaaa cagcgatttt
     7561 tggctcagaa gtgatgttga caccctctcc agtagataag attccagatg gccctacaac
     7621 cccggagatc gcttatcaaa tggttaaaga cgagactttc gcacaaacac agcctcgctt
     7681 gaacctagct acattcgtta ctacgtatat ggacgagtac gcgacaaaat tgatgaacga
     7741 agctatcaac atcaactata ttgacgaaac agagtatccg agaatcgctg ttatgaacgc
     7801 caaatgtatt aatatcatgg cgagtctttg gaattctccc gagcaagaaa aatggaaaac
     7861 cggagccttg gctatcggtt cttcagaggc ttgtatgcta ggtggtgtag ccgcttggtt
     7921 acgttggcgc aaaaagagac aagcacaagg taaaccaact gacaagccta atttcgtgat
     7981 ctctactggc ttccaagtcg tatgggagaa attcgcccag ctatggcaaa tcgaaatgcg
     8041 tgaagttccc ttgactttag acaagacgac acttgatccg gaagaagcgc ttaagatgtg
     8101 tgacgagaac acgatttgta tcgttcctat ccaaggtgta acatggacag gactgaacga
     8161 tgacgtagaa gccttggaca aagcgctcga cgcatacaat gccaagaccg gttatgatat
     8221 acctatccac gtagatgccg ccagcggtgg ttttatcctt ccgttcttaa gcccggagac
     8281 aaaatgggac ttccgtttga aatgggttct ttctatcagc acatccggac ataaattcgg
     8341 attggtttac ccgggattgg gttgggttgt ttggaaagac aagaaatatt tgccggaaga
     8401 aatggcattc agcgtaaact atcttggagc gaatatcact caggttggtt tgaacttctc
     8461 tcgtcctgcc gcacaaatcc tcggacaata ctatcagttt atccgtctcg gattcgaggg
     8521 ctacaaacaa atccaatata acagtatgga aatcacgaaa tacatccacc aagaaatcgg
     8581 taagatggcc ccattcgtta attacagcaa cgaggttgtg aatccattgt ttatttggta
     8641 catgaaaccg gattacgcta agaacgccaa atggacactt tacgatttgc aagataaatt
     8701 gcaacaaagc ggttggatgg ttccagcgta tacactaccg aagaagctgg ataactacgt
     8761 ggttatgcgt gtcgtagttc gtcaaggttt cagccgtgat atggccgata tgttattagg
     8821 tgatatcaag aacgctgtag aggcattgga gaaacttgaa tatccgactc ctactcgcat
     8881 cgctcaagac aaaaacgttc cggttaaggg taaggtattt actcacaccg caatgagcaa
     8941 cgctaagaaa taaaaacaaa attcatcaag gcgtgcatga aaggactatc agtgttttca
     9001 tacacgcctt ctttaatcca attcatatat ggacaaaaaa ataacgatcg cccaaataaa
     9061 ggaagtagct caacaggctt acgatcttta caagacaaat acggatggta agaatgccga
     9121 ttacattcct tatctggcga atatcaataa aaatctattc ggaatcagta tttgcctttt
     9181 aaacggacaa actatcgagg tgggagattc cgaatatcgt ttcggtatcg aatccgtatc
     9241 gaaagtacac accgctatct tggtactgcg ccaatacgga gcgaaagaat tattggagaa
     9301 aattggtgcc gacgctaccg gattgccatt taactccatc atcgctatcc tattggaaaa
     9361 cgaccatcct tctaccccat tggtaaatgc cggcgctatc acggcttgta gtatggtgaa
     9421 gcctgtcggt gattccaaac agaagtggga tgctatcgta gccaatatca cggatttatg
     9481 cggaagcgca ccgcagttga tcgacgaact ctacaaatcc gagtccgcaa cgaacttcaa
     9541 taaccgctcc atcgcttggt tgctaaagaa ttacaatcgc atttatgacg atccggatat
     9601 gtctttggat ctgtataccc gtcaatgttc tttgggtatc acggctaagc aactatctgt
     9661 cgctgccgct acggtcgcaa atttaggtct caatcctgtg acaaagaaac aagtattcga
     9721 tgcagagtta tctccgaaga tcacttccat gatctctacc gtaggttttt atgaacacac
     9781 cggtgattgg ttgtacactt ccggtattcc cgcaaaaact ggtgtaggcg gtggtgtcat
     9841 gggtgtactt cccggacaat tcggtatttc cgcattcgct cctcctattg accaagctgg
     9901 taactctgta aaggcacagc ttgctattaa gtatgtaatg aataaactcg gattgaacgt
     9961 gttcaacggt caccgtgtga cgatcgttga ctaatagaca gaatcagttt aaacgagaag
    10021 tagtatagaa aaagtgtttc attacgatgg gctgttatac catctaaatg aaacacttta
    10081 ttttttgtat caataaaaat cggatcaatt ctccgacacg acccaagccg aatcgtatac
    10141 ttccgtattc ggggtcttat aatacatatc cttttcttga ggaatgctta atttataggt
    10201 cttcccacct gtcaccaact tccgatcacg gagccaagga ttaaaacgtt tcaagtccgc
    10261 ataagtgatc ccatgctctt tagcgaaggc cgacagattc tgtatatctt ggcttacagc
    10321 cacgtctacg gtagggatcg gcttatacag gtcacgggca cgaagcacaa aaccgtattt
    10381 cgacggattc tcgaaaattt gcttgatcgc catgattcga taaatataac gggtagtctc
    10441 ctccaccagc cagagatcaa aggaggaatc cgcatcttgt ttgaccagct caccggatat
    10501 acgtcccatg ccgccattat aagaagcggc taccgccgcc caatctccat atttcttata
    10561 ggcggctttc aaatagcggc aagcggcccc agtagctttc tccacatggc aacgctcgtc
    10621 gaccgtcggg gtgattgtca aaccatactc ccttgccgtg ccctccagta attgccacat
    10681 cccgacagca cgagccggag aggatacacg ggggtccaaa tggctttcta tcaccgctag
    10741 atatttgaaa tcatcgggaa tgccgttcgc cttcaagatc ggctcgatca ccgggaaata
    10801 acggttcgcc cgcttgatca gaagcatcgt cgtagaatgg aaataagtaa agctactcaa
    10861 ttcacggtca taggcttccc gcatatcata gcgggtaata tcgattagtt tcccacaaaa
    10921 aggaaccgag gacggaacat ccggagacag ggtcatggac gagacaaccg gacggctctc
    10981 tatcactttt tccacgtcat tcgaacccat cgagatacat gcggtcaagc aaacgacgcc
    11041 tccacataaa aaactagcta aattattctt ggatattctc attttcatct tgaattgttt
    11101 taggtctaag aatgtttata tcgccttttt ccttgtactt aatgccatcg gaaccttcgg
    11161 cttctatcac ataaaaatac acacccggct gaacgtattt accgcccttc tttccatccc
    11221 atccttgggc cggatctgtc cagtaataca tctgtaggcc ccagcgatta aatatccatg
    11281 ccttaaattt caccaacgac ttataggcaa cccggaactc atcattaatt ccgggcgtgg
    11341 tacccgggga gaatgcgttc ggtatcatca gataagactc cgagatatca atctgaacct
    11401 catcttccgt gctgcaagta gtgctttggt cgcttacttc caacttgatg ataaaagtcc
    11461 cggattggtt gaacgtataa tccacttcct cacccgtaaa acgaacaacc ggattatctt
    11521 cttccccttg ccgatagatt ttccaattaa acagggcggc tgtcggcgta ttcgcgatag
    11581 ccgagaattg aacagtggcg ggagcgcaat aaccgctctt cgtcgtattc atattcgggg
    11641 cctcttgctc aatcagcaac gtgtctatat gagcatctac cgcagcggcc tgatattcat
    11701 cgatacaaag cgtgacctcc tttccaaaat gacgagcgaa ataatcgcct ttcacacaga
    11761 tctccgtatc acaccaagga gcgggaatgg atttaccgaa caaattaccc tcgatgaccg
    11821 ccgtctcttg tttagaggta tattcttttt tatccgaatt gtattccaat gtattataaa
    11881 taacatcaaa ttggcgagac agttcacgtc ttgttcccgt attcggccaa taataataaa
    11941 taggttggat cgtacctgtc ccagccaaga ccaatccgct acatggatcg ctattatcag
    12001 agacatgcag gttggatatg tttaaggtgt atttgctgta atcaacgatc cagacgtaac
    12061 gagatacggc tccttcctcg acaaaatagc catatccctc ctctacattc cgaatggtgg
    12121 aagtagttcc attttgggtg gaagcgactt tctcagcctc caatcgtttg gttttataac
    12181 ggtaccattg atgcgaagaa gaagaggatg aagtataact aatcgtcacg ttatccattc
    12241 catacaccaa gtagacctca agccgctcag cggaatcgcc ggaactctgc gatgctttca
    12301 tcggactacc acttcctccc gtgaccacat attgggcata cgagacagcc actacaaaca
    12361 caaaacttag cgataacagt atctttctta attccttctt tagcatatat agtctaaaaa
    12421 ttacggttcc aaaattaggg aaataaaagg acatacgtag catgataagc aaaattcact
    12481 atctttgtca caaaatactc cgaacagcaa atgaacaaga ttagtatata cgcattgacg
    12541 ttctttttaa gtttatcgag cgtaaccgtt tattcccaaa agaataataa gcaagttatt
    12601 tttactaacg aacaagggag cgatatattt tatcatacca tcgaacgcgg acaaaccgta
    12661 tacgccatag cgaccatgta tggcgtaagc gtagaggata tttatcggtt gaatccggaa
    12721 agtaaagaag ggatcaaggc cggttctacg ttaagaatcc cgcagaagga ctccgctatc
    12781 gcaccttccg gcaaagcaga taactataca taccatacga tccagccgaa agagaccttg
    12841 tactctttat ccattaaata ttcagtgccc gccacggata ttatcgccgc caatccgggt
    12901 ctctccacat cgacctttac gattggcaag aatatccgga tcccgccgac acgactggaa
    12961 accttgccta ctacggaaaa aaagaccgta cagaaggaaa tggaatatac catacagaaa
    13021 aaagagacca tgtaccgtat ctgccggaag ttcgatattt ccagcgtgga gcttttaaga
    13081 ctcaaccccg agctgaaaaa cggagtgaaa gcgggcatgg ttatcaagat accggtagcc
    13141 agtgaagaag tgatcaccca aaacataaga cagccggaag agcgtgaggt gaacgccctc
    13201 ctctctactc ctaaagatat aaagaaggtg aaccgtatcc aagtcgcctt attgttgccg
    13261 ttcatgacga acgagacaac gcaatcatcc gcaacctccc gtttcgtgga atattacgag
    13321 ggattgctat tggcggtcga cagcttacga aatatgggaa cctctatcga gctatcggta
    13381 tatgatactg gaaacggtac gaagaaagtc aaggagatat tgaaagaaga tgcgttatca
    13441 aacgctaatt tgatcattgg tgccgtacag aatgaccaaa tcggattgat cgcagatttc
    13501 gctcaaaagc acaatatcaa atacgtgatc cctttcacct ccaagaatga tgatgtcttg
    13561 tcaaacgcaa atgtttatca agtaaacacg cctcattcct acttatactc caaggcggcg
    13621 caagccggat gcgatttatt ctcggattac aatatcatac ttgtcaatat aaaggataaa
    13681 gaagaaaagc cggaatttat caaagccttc aagacggaga tgcagcaacg cgatatcccg
    13741 tttaaggaag taacttataa aggggacact ttcgccacgg atatagaggc agccatggta
    13801 agggacaagc ggaatgtggt attgccaacc tccgcctcct tagatgcggt gaataagatc
    13861 aaggcaccgc tccgtatgct ttccgagttg aaagaggagg agaaagagcc ttatatggtc
    13921 aacctattcg gttatccgga atggcagacc tatacaagag agtgtctgga ggacttctac
    13981 gcattgaaca cctatatcta tagtaatttc tatgcggaca acttatctcc ggaagtccat
    14041 agcttttatt ccgattataa aaactggtat agcaagaatt taatcaacac attcccgaaa
    14101 tatggaatcc taggctttga cacgggtatg tatttcctag gtgccatcaa taaatatggc
    14161 tcgaacttcg agaataatct agacaagatc cattataaga gcatccagac cggattcgat
    14221 ttccatagag tgaataattg gggcggtttt atcaatacga acttgtttat tgtacattac
    14281 aagaatgatt atacggtaac ccgcagtgag gtaagataat tgatatgatg acgaaaaaga
    14341 tatttgtagc gatatttctg tgcatggcaa gcttatcgat ttgccatgcg cagaaaagta
    14401 cttttaagca agagcttgcg gttggagcgt ccttcggatt aaatttctct agcgtaagtt
    14461 ttgccccaaa agtccctacg aagatgaaac ttgggtttaa cgggggagcg acgatacgtt
    14521 ggaatacgga acccaattta ggcatacagg cggaattgaa ctttacccaa catggatggg
    14581 aagagaagtt tgaggagaaa cctcaatata aatatagccg tacggtaaac tatatggagc
    14641 ttccgttctt gacgcacatc catttcggaa gcaagcgagt gcgtgtattc gtcaatctag
    14701 ggcctaaaat cggttatgcg ctgagcgaaa gcacggagtc gaaccttaat ggcgagaacc
    14761 cgaacgcgaa ccgtccggac gaacaacata cattggaagt ccaaaagaag ttcgattggg
    14821 ggctttgcgg cggaccggga atcgagctcc gcaccggaat aggctctttc ctgttggaag
    14881 gtcgttatta ctatgcgctg ggcgatatgt tcaatagccg taaaggagac acattctcta
    14941 aatcttccag ccaaataata tccgcgaaac taacctatct gattcccatc tttagtaaat
    15001 aagggggatg gactcgtgat atcgtaacaa tcaattgaag atctgtgccg caagtaacct
    15061 cacacaaggg ataagaacgg tggaaagtat agccaagctc cggacgatct aatcttttaa
    15121 cacctgtgaa gagatctttt cacgctcgtg atacgatcgt ttcacccttg tgaaaagatc
    15181 atttcacatc cgtgaaaaga tctttggata caggcgtaca agctacttcc gataatacct
    15241 ttatccaaca ggaaggttct acagtaataa atcatgaata caatggggaa cgcatctaac
    15301 gatcattatt gttgaggtga cctactataa aagaaaaggc catccgtcac ggacagccaa
    15361 tctcattgtt aaccttaaat ctaataccat gaaaaacaca gtgcaaatat agagacttta
    15421 tgttatgcag cataattttc caacaagaaa agcttactca ttaactttat ttaagacaaa
    15481 catgctatac aacatagaat tcagctcttt ttatctcgtt ttttctatta atagcgaaat
    15541 actaccacta taaatatttc ttacctttgc atttataaac ataaatatgg attaatataa
    15601 gaaatcatgc taattatagg tatagcgggc gggactggtt ccgggaaaac tacagtggta
    15661 aaaaagatca tagaaagttt acctcccggt gaggtcgtat tactccctca agattcttat
    15721 tacaaagata acagccatgt gccggtagag aaacgtcaat atattaattt cgaccatccc
    15781 gacgcatttg attggccgct cctctcagag caagtcacct tgctgaaaga ggggaaatgc
    15841 atcgagcagc cgacttattc ttatcttacc tgctgccgat tgcccgagac cattcatatc
    15901 gagcctcgtg atgttgtcat catcgaaggg atcctcgctt tatgcgaccc tcaattacga
    15961 gacttgatgg acttgaaagt atttgtcgat acagattcgg acgaacgtct tatccgtgtg
    16021 atccaacggg atatgatcga gagaggacgc acggcggaag cggtaatgga acgctatacc
    16081 cgggtactaa agcctatgca cctgcaattt atagagccta gcaaacgata tgccgaccta
    16141 attatacccg aaggaggaag caaccagatc gccatcaata tattgaaaat gtttatcgag
    16201 aacaatctgg ggcttcccca tacagataat caataaacca atcgttccga cagggatctc
    16261 cccaatataa atgcgtgtac cccgccaata cgttcttgta gcgatatagc ggggtatccg
    16321 tttgacctcc tttcgccgta aaggctttcg ctaccgaagg cagcggactt tccataggca
    16381 cgatccggga ataatggaac tcatgccctc gtaagacatc attcttatag cataaagtcc
    16441 gataccctaa acgtaacttc atgttctcca tcgtggcgga ttgcggtaat acaccggcca
    16501 ttggataggc attcccatcc gtaccgataa tctctttaca gagatacatc atccccccac
    16561 attccgccag caacttgccc cccacttcca caaaggaatg aatcgattca cgcatcccgg
    16621 aattcatgct caactccgat aaatataact cgggatatcc acccggtaaa tagacaaaat
    16681 cggcctccgg taaacaatca tccctcaatg gactgaaata ggtaatcttg cctagagtag
    16741 ataagaaatg tatattttcc tcatatgaga aattaaaagc gggatcacgg gcgatggcta
    16801 tatttaagtt tgcctttgaa acagtcctca tgacttcctt aacccgagga actggctgtc
    16861 gctctggcaa agccgtgatt gccaacaggc ggtctatatc cacatgctcc tccaccaagc
    16921 aagcaacccg gtccgcaaac tcctcaaagc aaaaatcctc atccaacgac aaccccaaat
    16981 gccggctcgg gatctctaca tccgcacact tcggtagata gcctaacgct tccacacccg
    17041 catcctcaca cgcttgtctc aagaaagaat aatgactctc cgacgccacg aaattaaata
    17101 ccgcccccac gacattcaga tctttccgaa aattccggaa gccataaagc aagggagcca
    17161 ccgaataagc cgtactttta gcgttcacca ccaatacgat cggtatccgc aataaaccgg
    17221 agatctccgc actactccct cgcatggcat cgtagccatc gaacagcccc atcacccctt
    17281 cggtcacggc tacatccgca ttcgaggtat accgggcata taaatccttg atatgccctt
    17341 ccgacatcat gaaaccatcc aaattcacgg aagcgcaacc agccgccatt ttatgatgac
    17401 gagtatctat ataatccggc ccacacttaa aaggctgcac ccgtaaagaa cgacttctca
    17461 aggcacgaag caatcctaag gtaaaagtag tcttcccgct tcccgacgaa gcggcaccta
    17521 ttagcaaatg agatctcatg tattctgttt ctaatatatc tgggaaacaa agatatgaaa
    17581 ccaactcgta aatgtaacat agaaataaca taaattcttg ttatactata aatcgatcct
    17641 attatattcg ctgcatgaaa caaaaagaat aagtagttag tgaaaacaag attaaccata
    17701 ttatatagta tttgttgcat atcaatgttt cagggcacga ctttttccca aacaagcact
    17761 tttacccacc ggaacgacag ttccaatcta gcgcctttat ctacttgggg aagaatccaa
    17821 agacaaaccg acaagataat taccagcaat gttttccaaa tgacctatat cggggtaccg
    17881 ttgatcgtta gcggtttgat tatcaagaat gaggacgatc attttcagag tttgcgcaat
    17941 acatatattc caaatttccg ataccattac gacgattacc tgcaatatct acctgccgta
    18001 gcgatgcttg gcttaaaaat aggcggtgta caaggaagaa gctcttggtc ccgaatgctc
    18061 gtatccgaag ccatcaccgc cagtatcatg ggagcgacca tcaatacggt gaaacatacg
    18121 gcaaatgtca cccgtccgga tggttcgaac aatcattctt tcccttccgg gcacacggcc
    18181 atggcattta tggccgccac catgttgcat aaagaatacg ggacgacccg tagtccttgg
    18241 tatagtatag gaggctatac ggtagcgacc gccacggccg tatcccgtat gctcaataac
    18301 aagcactggc tatcggatgt aatggttggt gccggaatcg ggatcttatc gaccgaggtc
    18361 ggatattttc taacggatct gatcttcaag gacaaaggta tcacccatag ctatctggga
    18421 ttcgagacat tcaattacca gcgaaatccc tcttttttcg gaatctatat ggggtttagc
    18481 ttgatgccga caaagtttaa tctggctccg gatgtgcgat taaaagcatc gccgggaagt
    18541 acggccggat ttgaaggcgc ttggttcatg aatcgttata taggcttcgg cggacgcatc
    18601 tcggcgacaa gcatgccttt atcccttacg aaacccttag cgaatccgac agttcccggt
    18661 acgacctatc aagtgaacgc cctaaaatcc gatcctctnn nnnnnnnnnn nnnnnnnnnn
    18721 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18781 nnnnnnnnnn nnnnnnnnat ctcggcgaca agcatgcctt tatcccttac gaaaccctta
    18841 gcgaatccga cagttcccgg tacgacctat caagtgaacg ccctaaaatc cgatcctctc
    18901 gacatgatcg gcggatacat cggctcctac ctatcgtatc cggtgaccaa tcgatttctc
    18961 ttgggcacga aactgctaat cggatgtaat tacagcccag cctcccgaat atcagcattg
    19021 ggcgtggagg aaggcaaacc ggaaacgatt gagaaagaga tcgtaaacac gaataaagcg
    19081 tttaatatag gatatagcac aaacgcctct ttctcataca tattgcatcc taatctaaat
    19141 gtgcgggtat ttctcgatta tacttttatc ccctcacgat tcgtatcata catagccaac
    19201 cccaaaaaag aaaccgatcg cttcgagcat cataagacct tacaggcctt gacgctcgga
    19261 gcatcggtaa atatcatgct ttggtagatt taaaaatcaa tattgctcct tctcgttcgg
    19321 gaagtcttga gatttcacgt cctcgatgta cgcttgtacg gcacgggtaa tctcctcccc
    19381 taaattagcg tagcgacgta agaaacgggg agaaaagcct tgattgatac cgagcatatc
    19441 atgcataacc aacacttgac catctacgcc tccaccggcg ccaatgccga taaccgggat
    19501 cgtaagctcc gaagcgacac gagctgccaa ctccgccggg atcttctcca gcaccaaggc
    19561 gaaacaacct atctcctcta gcaaatgggc atcctcgatc agtttattag cctcggcctc
    19621 ttcacgggca cgtaccgtat acgtaccgaa tttattgatc gattgcggcg tcaatcctaa
    19681 atgtcccata attggaatac cggcacacaa gatacgttcg atagattccc gaacctcagc
    19741 cccgccttcc aacttgatac aatcggcatg cgtctctttc atcacccgga tagcggaggc
    19801 caaggcttct ttagagtttc cttggtacgt accgaaaggc aggtctacca ccaccagcgc
    19861 acgattcacc gctttcatga ccgatttacc atggtaaatc atctggtcga gcgtaatcgg
    19921 caaagtggtc acgtttccag ccattacgtt agaagcggag tctcccacca agatcacatc
    19981 cattcctgct tgatcgatca atttcgccat cgaataatca taggcggtaa gcatggatat
    20041 tttctcgcca cgctgcttca tctctatcaa gcgatgtgtg gtcacctttc tattatcatc
    20101 tacttttgcg acagacatat tatattttta ttaattgttt cggccgcaaa ggtaagtatt
    20161 attatttatt ttcaagacaa acattcacgg cacttaagcc tctgtcgcca cgttcaaggt
    20221 cgaacgtcac gatatcgttc acggagatat catccacaac attgttcacg tgaaagaaat
    20281 acttttccgt ccccgacaag tcacggataa acccgaaccc ttttgcctca ttaaaatagt
    20341 ctaccctgcc ccttaagata acgggagcca catcctcttt cttaggagtc gagatcaaga
    20401 tatcttcctg atttatctct tctttttgac gaagttcggg agggacagag gtgatcatcc
    20461 cattttcatc cacataagcg atcatgtcct caaagctagt cgccttgccg gacgattttc
    20521 tttcctcttt cctgttctgt ttctctactc ggcgggcttg tttctttttc tcgttttcac
    20581 gcttaccaaa tgatgcgtat tttgccatac agtcgatttt aatttatact agggcctcac
    20641 gttccgtgaa gcgttgttta tactaactta gcgtgagaat tgatgattaa aggagagatc
    20701 cgcttaataa taatataaaa agaagaacta tgtcgataat gattctagac tcaaactttc
    20761 gcaaagataa taaaataaac ggagaaaacc ttatagatcc tctcatttaa gaataaaaaa
    20821 acttactttt gcatcctata ccaaaaagca tttatgaaac tacttttttt tgatttagag
    20881 actaccggca taaaatactg gagaaatggc gtccaccaaa taagtgggga gatcgtaatt
    20941 gatggggtta cgaaggaatc ttttaatttc aatgtctgcc cgcatcccca atgtgagata
    21001 gaggaagaag cgcttcgtat ttgtaacgtg tccaaggaac agatacaagc ttatcctccc
    21061 atgcgagagg tgtacgttaa atttgtgaac atgctgtcca aatacgtgga caagtttgat
    21121 aaaaaagaca agttcttcct cgttggatac aacaacgcct ctttcgataa tcacttcttg
    21181 aaagccttct tcgtacagaa cggagataat tatttctact catggttctg ggtgaactcg
    21241 atcgacgtaa tggtattgtc tacccagcat ttgatgcgca aacggcatga gatgacagat
    21301 ttcaagcagg aaacggtggc aagggcttta ggtatacaaa tagattctgc gaaattgcac
    21361 gacgcgtcct atgatattca attaaccaaa gaaatttata ataggatatc ctccctctca
    21421 tttatgggtt gattgattct ttttataaat tatcgttttt gactataggt tgatttaatt
    21481 atctttacgg cgtagaatca atttttaaga tgtctgtgaa acatagtatc cgtattttct
    21541 tctttattat cgctctcgta tatacaggtt ccttgactgc ccaagaaaag gcgtatccga
    21601 aaaacggaga gggcatcact ctttttctca aacgcttcaa ccgtaccggc gggacgtatc
    21661 agaaagagtt tatcgagctt aataaaggga agttgggtaa aaataacact ctgcgcatgg
    21721 gcgtaaaata taccttgcct ccgctcgcct ccgcccctca gaaaaagaat tatcagcccc
    21781 tattcggcaa gtcgctagcc agttacaaag taacctcttc cgatttaaag ggagcttgct
    21841 tttatctggt cagcggtcat ggcggtccag accccggagc gatcggtaaa atgggctccc
    21901 atgaattgca tgaggatgaa tacgcttacg atatcatgct acgtctggca cgcaatcttt
    21961 taacgcgagg cgcaaaggta catattatca tccaagacgc aaaggacgga atacgtgacc
    22021 agcaatttct caataacagc aaacgggaaa cttgtatggg tagtccgatc cccctcagcc
    22081 aagtaagccg tctggatcag cgttgcgcca agataaacag cttgagccgg aaagataaag
    22141 aaacttataa gagagcgata ttcatccatg tggacagccg gagccggcat caaaggaccg
    22201 atgtcttttt ctatcataag cccaaggatc aagcgagcaa gcgcttggct aaaacgatga
    22261 aatccacttt ctcgcgcaaa tacaaccgcc accagccggg ccggggattc tcgggcacgg
    22321 tagacgatcg taacttatat gtattacgtc acacgacccc gacctccgta ttcgtcgaat
    22381 tgggcaacat acaaaaccaa tacgaccaac aacggatcat cctcagcaac aatcggcaag
    22441 ccttggccaa ctggctttgc gagggttttg tcacggatta taattattat aggaagtagc
    22501 atccctaatg atctattata ctaacacata tcctgcggca gaaatgttat atgagcgatc
    22561 ttaacagcaa tgtaacatat atttcatttc tccgaaataa gaatatccgt tctttgccaa
    22621 aaataattat atttgtatat ggagagccgt aaggcactct tttaaaaaca gaacagctta
    22681 tggcaacaac tcgtattctt gtagtggatg atgaagagga tttgtgtgag atccttaaat
    22741 tcaacttaga aatagaaggt tatgaagtag ataccgccta tagtgcggaa gaggcattga
    22801 aaaaggatct gaccgtttac aatttattat tgttggatgt catgatggga gaaatctccg
    22861 gtttcaagat ggcacgtatc ctgcgacaag atgagaagac ggccaatacc cctatcatct
    22921 tcctcacggc caaagatacg gagaacgata tgctcacagg gttcaatctc ggggcggacg
    22981 actatatctc caagcctttc tccatccgcc aagtgatagc gcgtgttaag gccgtactaa
    23041 gaagaacttc cgagaaatca aaagaaaaag agattgagaa actcgagtat gagacattag
    23101 ctcttgatac gaaacgcatc aaggctacgg tagacggggt ggaagttcca ttgaccaaaa
    23161 aagagtttga gatactaaaa cttctattgg aaaataaagg gaacgtcttc tccagagagg
    23221 aaatactgtc tcgcatctgg aaagacgagg tatatgttct agaccgtacc atcgatgtca
    23281 acatcacccg gttacgtaag aaaataggtc cttatggaaa gaacatcgta actcgcttag
    23341 gtttcggtta ttgttttgaa tgctaatatt gtcgctgaat catggtaaag atagatggtg
    23401 agaaaagaca ccggataccg tttagccaac ggcttttctg gtcggtcttt tttatgttct
    23461 tgggctttac ggtctgtttc ctgctattcc aatatcagcg ggaaagggag ttcgcgcaag
    23521 aaaagttgaa caatgtgttg agtaactata attaccaatt attccgcaaa tgccaacaaa
    23581 gtacggacat caac
//
LOCUS       DBMDTB010000065        23316 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_753_length_23316_cov_11.858367, whole genome shotgun sequence.
ACCESSION   DBMDTB010000065 DBMDTB010000000
VERSION     DBMDTB010000065.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 23316)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 23316)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23316
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_753_length_23316_cov_11.858367"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..1203
                     /locus_tag="ACZPB4_11135"
     CDS             <1..1203
                     /locus_tag="ACZPB4_11135"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008781069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HIR1098801.1"
                     /translation="ANRLAKALGKSGVEVSMLVRDRKTDHVKVFSVNNSWISHRLNSF
                     RFIWERLIIFICNFFSKKNLFQVSIANTGTDLSKHPLVQQADVIHLHWVNQGFLCLSD
                     IKKLVNTGKPIVWTMHDLWPATAICHYPGGCEKYISNCYQCPMLKRNPFFDLAASVFK
                     EKGKIGLSKITFVGCSRWIMEEAKKGNWLRTACFTSIPNPIDVTAFKRMEKRVARKRF
                     GLPEDKFLLLFAAAKLSDTRKGAIFLIEACEKLKEKYQDRIEIVLMGNSSEELISQFP
                     FKVNTLGYISDQDSMISVYACADMFVIPSLEDNLPNTIMESMACGTPCVGFETGGIPE
                     MIDHLKNGYVAKYKDTEDLAEGIKWIIDSRESLQLSEACIRKVHDCYQESVVAGRYID
                     LYRSLTSP"
     gene            1298..3154
                     /locus_tag="ACZPB4_11140"
     CDS             1298..3154
                     /locus_tag="ACZPB4_11140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008781070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding domain-containing protein"
                     /protein_id="HIR1098802.1"
                     /translation="MKEYLSNVLEILEEKGVLNESYDLEFKSAKGGLPRSLWESYSAF
                     ANSEGGTIILGVSEKDNYCYLDGLGEDVVRKWLDDFWNQINNKEKVSVNLLTAKDVRI
                     EKVKDDINVLIIRVPPASFRYRPVYIGTDMLKGTYRRDHTGDYRCMPEEVKRMLADSL
                     PDKPDSLVLEHSTIEDLDLPTLDQYRNILRSVKPMHPFLTLDNLPFLQRLGAWKVNRA
                     TGTYGLTAAGLLMFGKTQSIQEFFPDYHVDYQEISNQGSRWIDRIYPDGTWEANLFQF
                     FHRVWPKLSFSLPKPFLLENGRRRDEGAIHEALREAFANSIIHADYRGQGGIVIKKYP
                     DRFLFVNPGYMLVPLEQYYKGGCSVPRNTTIQTMFSLLGYGEKAGSGSLRIMSAWASA
                     HWRKPFISMTNRPDRVCLDLKMEVLLPKDSLEHLEYIFGKDVRNMYGDALVILSTAEI
                     EGVVSNLRLQGLLNKHSSEISIMLKDLCSQGYLNPENKGRWTSYHLNKGIGLKQGSLF
                     ENLDGHLNEKMDTSDKKDGHLNEKMDTSDKKDGHLGRNMQEIKSSELKSYIVEICSSR
                     YLTIEEIAVKTRRTSKYLKNKIVSQLLKDGLLERLYPTTPNHPNQAYKKKQQ"
     gene            3151..3912
                     /locus_tag="ACZPB4_11145"
     CDS             3151..3912
                     /locus_tag="ACZPB4_11145"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009101 - glycoprotein biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HIR1098803.1"
                     /translation="MNQQPTFSIITITYNAERWLERTILSVLSQSYPDIEYILIDGAS
                     KDKTVEIIKQYESGISSWISEPDKGLYDAMNKGLKLATGDYVWFLNAGDTLYTADTVQ
                     RIVASLKKKVSLPDVIYGETRIVDAEGRSLGMRRLKAPEKLNWKSFRMGMLVCHQSFI
                     SKREIAPLYNTEYRLTADYDWCIQCLRRSKRIHNTRLILSNFLEEGLSSVNRKASLKE
                     RYEVMCKYYGKVSTILLHGWFAVRFYFAKWFKGRV"
     gene            3936..6440
                     /locus_tag="ACZPB4_11150"
     CDS             3936..6440
                     /locus_tag="ACZPB4_11150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HIR1098804.1"
                     /translation="MRSIMSKWGKHIAAIAVFLVLTVIYFSPAVFEGKVVRQGDTEKA
                     IGMGNSQMDEYEKTAQPGEFSAWSDAMFGGMPYVSGYGNPAPRFPGYLLVEKPLKALG
                     YMDAGMVFTGFVCFYILMCVMGVNWWLAIAGAIAFALASYNLIIIEAGHVTKAYVIAY
                     MPLTLAGMALLFKRKYLWGAVVFLLGVAFSIANTHLQITYYLLLLCFFVYLGYLFNKL
                     KEKAYKELGTVTAIMAGCVILAVLPNAQNMYAQWDLGQNSIRGATELTTTTPSGEKIS
                     SGLDKDYAFAWSYGKGELLTLLVPNAYGGSSGGMLGPDSELYKELRAKGVQVGKEVQA
                     PTYWGEKTFTSGPVYFGALVCFLFVLGMFVIRNPMKWWLFGGSVFLILLALGRNFDSF
                     NDFMFHYLPMYNKFRTVEMALVIPGMVFPIIAIWGLKEVLSETVSDALLKRGLIAALA
                     ITGGLSLILWLMPSMLLDFRSSFDAQYQLPDWYYNALLMDRASLASADALRSLVFILL
                     GAALLFWFYTSKDRKKVATFVGIGVAVLMLVDLWTVDKRYLNDSNFIRQKPTEVYKET
                     VADQEIMKDKDLSYRVLNLNNPFLETTTSYYHHSIGGYYAAKLRRYQELIDHRLQGEL
                     NSVIGAFQKAQTAEDLMGAFAACPSLNMLNTRYIIYNPEQPPLRNPFAFGNAWFVDKV
                     EVVENADAEIAALNTINPLTTAVVDKRFADEVKGFTPQLDSTATITLDSYRPNKLVYT
                     TKTNSEQLAVFSEIYYQPGWEVTIDGKPASHFRADWILRAMLVPAGEHQIVFEFRPQG
                     YITAAYITSFSSLIILLLLIGAVGYSVWKARKQKEI"
     gene            complement(6484..7611)
                     /locus_tag="ACZPB4_11155"
     CDS             complement(6484..7611)
                     /locus_tag="ACZPB4_11155"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HIR1098805.1"
                     /translation="MRFAILSPIYPYRGGIAQFSGMLYTELVKEGHEVKAFNFKRLYP
                     DILFPGKTQYVEAGDRAIEIESVRVLDSVNPVSYFSTVNAIRSYAPDVLIISYWMSFF
                     VPGYAHVANRMKKHCKVITLIHNAIPHELRFFDKPLASLLFKQCHGFIVMSDNVRYDL
                     RKLYPGAKYIQNPHPLYNHFGSKINKNEACRKLGIHPSKKNLLFFGLIRDYKGLDLLI
                     EAMGQLNEDYHLIIAGECYGSFEKYQALIDASPAKERIFVHCEYISDEEIPFYFSAAD
                     ALVLPYRSATQSGVVSVAYNYDLPMLSTPVGDFKNSIEKPGTGIVVPEISATALAQGI
                     EELFTPSQQATIPANISKEKAALSWETLTRKLLDFINSGFI"
     gene            complement(7714..9132)
                     /gene="ahcY"
                     /locus_tag="ACZPB4_11160"
     CDS             complement(7714..9132)
                     /gene="ahcY"
                     /locus_tag="ACZPB4_11160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004013 - adenosylhomocysteinase activity
                     [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylhomocysteinase"
                     /protein_id="HIR1098806.1"
                     /translation="MSQLFPTNLPYKVADMSLAEFGRKEIEIAEHEMPGLMALRQKYA
                     DQKPLKGARITGSLHMTIQTAVLIETLVALGADVRWASCNIFSTQDHAAAAIAADGVP
                     VFAWKGETLEEYWWCTDMALRFPEGKGPHMIVDDGGDASLLIHMGYRAENDAETINRK
                     GGNHEEQVILDTLNRILQEDNGRWHRTVAEMKGVSEETTTGVHRLYQMMEKGELLVPA
                     INVNDSVTKSKFDNLYGCRESLADGIKRATDVMIAGKVVVVAGYGDVGKGCSHSMRSY
                     GARVLVTEIDPICALQAAMEGFEVTTMEEAVKEGNIFVTTTGNCDIITIEHMTQMKDQ
                     AIVCNIGHFDNEIQVDKLVNYPNIKHTNIKPQVDKYTFPNGNSIFLLAEGRLVNLGCA
                     TGHPSFVMSNSFTNQVLAQMDLWQMAYEVGVYRLPKRLDEEVARLHLERIGVKLSTLS
                     QKQADYIGVPVEGPYKADHYRY"
     gene            complement(9319..10074)
                     /locus_tag="ACZPB4_11165"
     CDS             complement(9319..10074)
                     /locus_tag="ACZPB4_11165"
                     /EC_number="1.1.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose 1-dehydrogenase"
                     /protein_id="HIR1098807.1"
                     /translation="MTKTMEEKVALVTGSAMGIGLACAEAFAKAGYITVLADIRKPGE
                     QAEKLVAEGHKAVAYRCDVSNTQAVKEMIDWTVVTYGRLDAALNNAGIQTPQRPMAEI
                     TDDEFDRTVAVDLKGVWNCMRYEILQMLKQGGGAIVNTSSQGGVTGFPGQAAYIACKH
                     AVIGLTRTAAIDYAAKNIRINAVCPGVIRTPMAEDLMRRDPSLEKELVCDIPAGRLGK
                     PEEIANAVLWLCSPQASFVDGHALLVDGAFSIH"
     gene            complement(10187..11005)
                     /locus_tag="ACZPB4_11170"
     CDS             complement(10187..11005)
                     /locus_tag="ACZPB4_11170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIR1098808.1"
                     /translation="MDGINTLRYSDLFLAMYFDGGKSCLHRNHSHVLVYVYSGEMVID
                     EKGQITRLHKGECAFIRKDFSVQMTKQAWNGEQFKAIFLMFTMKFLCDFYSKLDRNTL
                     PKDAKRDQVSLYKLPSNRPDIVSLFESMTPYFNSKIQPTDELLQLKMVEGVYVLLNTD
                     KNLYASIFDFTDPWKIDILEFMERNYMNDISMEEIANYTGRSLSTFKRDFKKCSALSP
                     REWLIRRRLEAAHGLIRKGGRKVSEICFEVGFKNLSHFSKIYKIAYGVPPTEDI"
     gene            complement(11092..12741)
                     /locus_tag="ACZPB4_11175"
     CDS             complement(11092..12741)
                     /locus_tag="ACZPB4_11175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HIR1098809.1"
                     /translation="MELHNRTLGQWLEHWAETTPDKEYIVYSDRDLRFTWSEFNKRVD
                     DMAKGMLAIGITHGTHVGVWATNVPDWLTFLYAGAKIGAVLVTINTNYKQSELEYLVE
                     NADIHTMCITDGVFDGSYVDMVYTMLPELKTSQRGYLKSKRFPRLRNVVYIGQEKYRG
                     MYNTPEMLLLGQNIKDETLEAAKARVNCHDVVNMQYTSGTTGFPKGVMLTHYNIANNG
                     FLTGEHMKFTADDKLCCCVPLFHCFGVVLASMNVLTHGCTQVMVEKFDPLLVLASIHK
                     ERCTAVYGVPTMFIAELNHPMFEMFDLTSLRTGIMAGSLCPVELMKTVDEKMHMRVTS
                     VYGLTETSPGMTHSRIEDPAEVRYNTVGHEFEFTEVRVIDPETGEECPVGVQGEMCNR
                     GYNNMKGYYKNEAATNEAIDKDGFLHSGDLGVKDENGNYRITGRIKDMIIRGGENIYP
                     RELEEFLYHFPGVKDVQVAAVPSKKYGEEVGAFIILHDGVTATEEEVKDFCRGKIARH
                     KIPKYIFFVDTFPMTGSGKIQKFKLKDLGLKLLQEQGITPA"
     gene            complement(12754..13335)
                     /locus_tag="ACZPB4_11180"
     CDS             complement(12754..13335)
                     /locus_tag="ACZPB4_11180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIR1098810.1"
                     /translation="MGNNKIIGAKIKNIRESKQLSIEEVAERSGLGIEQIERIEGNLD
                     FPSLAPLIKIARVLGVRLGTFLDDQAELGPVVCRKKDSEADGIGFTNNATQGHKHMDY
                     HSLSQDKSGRHMEPFLIEIAPSEEGEDFILSTHEGEEFIYVLNGVVEINYGKNTYILE
                     EGDSIYYDSIVAHHVHAAADNKARILGVVYTPY"
     gene            complement(13495..13764)
                     /gene="rpsO"
                     /locus_tag="ACZPB4_11185"
     CDS             complement(13495..13764)
                     /gene="rpsO"
                     /locus_tag="ACZPB4_11185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HIR1098811.1"
                     /translation="MYLDSAKKKELFEKYGKSATNTGSAESQIALFTFRISHLTEHLK
                     VNHKDYATERSLKMLVGKRRRLLDYLIKTDIERYRAIIKELGIRK"
     gene            13935..15731
                     /gene="typA"
                     /locus_tag="ACZPB4_11190"
     CDS             13935..15731
                     /gene="typA"
                     /locus_tag="ACZPB4_11190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008147086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HIR1098812.1"
                     /translation="MQKIRNIAIIAHVDHGKTTLVDKMLLAGKLFREGQAEPDQFMDN
                     NDLERERGITILAKNVSINYKGYKINIIDTPGHADFGGEVERVLNMADGCLLLVDAFE
                     GPMPQTRFVLQKAIQLGLKPIVVINKVDKPNCRPSEVQEMVFDLMFSLDATEEQLDFP
                     TIYGSAKQGWMSEDWKEPKEDIAAVLDAIIKYIPEPKMLEGTPQMLITSLDYSKYVGR
                     IAVGRVHRGELKEGQDVMLCKRDGSMVKSRIKEVDVFEGLGRTKVDSVQSGDICAIIG
                     IDGFEIGETIADVNEPEPLPTIAIDEPTMSMLFTINNSPFFGKDGKFVTSRHIFDRLQ
                     KELDKNLALRVVPTDSADSWLVYGRGVLHLSVLIETMRREGYELQVGQPQVIIKEIDG
                     EKCEPVEQLTVNLPEECSSRIIDMVTKRKGEMTMMESKNGRMHLEFTIPSRGIIGLNN
                     AVLTASAGEAIMAHRFLEYQPWKGDIERRMNGSIIAMETGQAFAYALNNLQSRGRFFI
                     APGEEVYAGQVVGEHTKDNDLVVNVTKSKKLTNMRASGSDDKVSLAPPIVFSLEDALE
                     YIKGDEYVEITPNNMRMRKIILDETERKRQGR"
     gene            complement(15837..17591)
                     /locus_tag="ACZPB4_11195"
     CDS             complement(15837..17591)
                     /locus_tag="ACZPB4_11195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008781076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LruC domain-containing protein"
                     /protein_id="HIR1098813.1"
                     /translation="MRSQIWKQMVWVFCLLFLMESCVKHDIYQGEDPSVDPQEPTKEK
                     EDYIAQFENFENIQVSISSQHEGTLYSIYYEYPYEEGSLVKDPYLIGKTPIHMALEVP
                     KHVKKLYILRGDGELIESDVKDITIGSDTKSSLRATNAISDEVLHLINNKYFPEKAYN
                     VKSEDLYRCSDLKITETVFTSSFEKADIWLTYISDGGMSKGNSNMHGKIWFYTYPSEK
                     MENLTLDDCTFYGKTNGAIQVTDFNTINQGDNYIFYSKEEQPKAQAGEYTRIPLGRFD
                     KGLNVGFVYRGTDRPQFSTPALNGPDNNKVPDNGTFSHNYVGHTLKYGNSSFKIEKNV
                     ANGFIHHIQEGDFEGNVLGMENRCPNYRAYDGDYNDMLCLIESNPVAIEPAEPVTPPV
                     IESQTNKKGFLLFEDNYPNQGDFDFNDAVIYYSITAYTDKSTADVYAQLLAKGCTFHN
                     QFGFKDANGLTPFFSDVNGYVNVRKFDKEPESGITKTLTYSATQLIMPYIDNGKGPVS
                     KNVKNTDLYPYVLDIPYSESQPFRWCIENKSIDEAYNFDQDYRKAHGDWYETPKDESL
                     VIQFTTPDEEKKDPENKE"
     gene            complement(17801..19492)
                     /locus_tag="ACZPB4_11200"
     CDS             complement(17801..19492)
                     /locus_tag="ACZPB4_11200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098814.1"
                     /translation="MNKKFLLPFFVLAAILTLSSCSNKLKPLAEQYIKAEPQPLEAIG
                     GKVPVTINATFPAKWFNKKAVVTVTPVLRYQGGEAWGTSYTYQGEKVKGNNQVIPQKE
                     GANVTMKSSFTYKPEMKKSELYLTFDAKIKNKTVKLPDVKIGEGVIATSELADAATAT
                     AAIAADKFQRIIKEAHDANIMFLIQQANLRAKELNSDAIKEWKDLVKNADEAPNQNVA
                     IEISAYASPDGGFKLNNTLAENREGNTTKYLNKELKKMKVDAPVDARYTAQDWEGFKE
                     LVSASNLQDKDLVLRVISMYQDPETREKEIKNISAVYSDLAETILPQLRRSRLTANIE
                     IIGKSDDEISALAKSNPSELNIEEILYAATLTNNDGEKMAIYTKASELYPNCYRTWNN
                     IGMMAFKAGDLAKAEQMFNKSNSIKNNASANMNLGLIALTKGDQAKAQQLFGNAAGVN
                     ELSEALGVLYLEQGEYAKAVNSFGSVKTNNAALAQILVKDYSKASQTLNGVAKPDAIT
                     SYLKAVVAARTNDANGVVSNLKAAIAADKSLAKEAAIDLEFAKYATNSDFSALVK"
     gene            complement(19758..>20024)
                     /locus_tag="ACZPB4_11205"
     CDS             complement(19758..>20024)
                     /locus_tag="ACZPB4_11205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="T9SS type A sorting domain-containing protein"
                     /protein_id="HIR1098815.1"
                     /translation="GNPVSNEKLEANEQVLIHLGPEKGMVHLVLPDGIEKATYTLHSA
                     QGKVSENGEITDRQATLHFLKLTSGVYFLTVHYGEEHYTQKIIF"
     assembly_gap    20025..20124
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<20125..21626)
                     /locus_tag="ACZPB4_11210"
     CDS             complement(<20125..21626)
                     /locus_tag="ACZPB4_11210"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like serine peptidase"
                     /protein_id="HIR1098816.1"
                     /translation="MKKLTSLYIVFLLTMLGFQGNLKAQVSHGGRPLPLSLMRSTNGQ
                     MFKEMPPFDVQEELRIDSLNESDLRSGFRFAYKFITDYNRYNSGVTFTGPDGTRVWRL
                     GIYSPGALSINVLFTEYELPEGAQLFLYNEDQTQILGSFNHLNNSELNLLPVSPIQGD
                     RLIIEYQEPANASFQGRLTVGEVNHGYRSLRGLEPGDNTSLIGKIPPLACYQDGTNDY
                     AQWGQSVVLLIIDGSVGCTGTLINNTDNDGKPYLLTASHCLNKQFTMKNPDYEKIAGS
                     IVCFFNFNSPFCDPILRGTEEMSTASTYFKAVNEMADMALLELTATPPVYYRPYYAGW
                     NAQEVGPAPYTCIQHPQYSVKRISISDEDLAPFTLTDPNMIFYENAHLHVKTWEVGYT
                     ASGSSGSPLFNADGEIIGALSGGQSSENSPKNDYFFSLKKPWDAIDTPERQLKYWLNP
                     SDDETKVCEGLDPYKSTPCFRLSNIYDSGNQENAECTLYPGSEKAYLFGN"
     gene            21752..>23316
                     /locus_tag="ACZPB4_11215"
     CDS             21752..>23316
                     /locus_tag="ACZPB4_11215"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005813403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004333 - fumarate hydratase activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate hydratase"
                     /protein_id="HIR1098817.1"
                     /translation="MATPPFHYEPMFQKGPDTTEYYLLTKDYVSVSEFEGKPILKVAK
                     EGLTAMANAAFRDVSFMLRRSHNEQVAKILSDPEATDNDKYVALTFLRNAEVAAKGVL
                     PFCQDTGTAIIHGEKGQQVWTGYCDEEALSLGVYKTYTEENLRYSQNAPLNMYDEVNT
                     KCNLPAQIDIEATEGMEYEFLCVTKGGGSANKTYLYQETKAILNPGTLVPFLVEKIKT
                     LGTAACPPYHIAIVIGGTSAEKNLLTVKLASTRFYDSLPTTGSEGGRAFRDVELEKEV
                     LAAAQNIGLGAQFGGKYLAHDVRIIRLPRHGASCPVGLGVSCSADRNIKCKINKEGIW
                     IEKLDSHPGELIPEELRQAGEGDAVKINLNQPMADILKELDKYPVSTRLSLNGTIIVG
                     RDIAHAKLKERLDRGEDLPQYIKDHPIYYAGPAKTPAGMACGSMGPTTAGRMDSYVDL
                     FQSHGGSMIMLAKGNRSQQVTDACKNHGGFYLGSIGGPAAILAQNNIKSIECVEYPEL
                     GMEAIWKIEVENFP"
BASE COUNT         5951 a         4818 c         5595 g         6852 t
ORIGIN      
        1 gcgaaccgac tagcgaaagc attgggtaaa tctggtgtag aggtttctat gttagtacgt
       61 gatcggaaaa cagaccatgt aaaagttttc tctgtaaata attcatggat ttcacatagg
      121 cttaattctt ttcgcttcat ttgggaacga ctgataatct ttatctgtaa cttctttagc
      181 aagaagaacc tttttcaagt ttccatagcc aatacaggca cggatttatc gaagcaccca
      241 ttagtgcaac aggcggatgt gattcatctg cattgggtga atcaaggatt tttgtgtctt
      301 tctgatatta agaaattagt aaataccgga aaacctattg tgtggactat gcatgatttg
      361 tggccagcta cggctatttg tcattatccg ggaggatgtg agaagtatat atcgaattgt
      421 tatcagtgcc cgatgctgaa acgaaatccg ttttttgatt tagcggcttc tgtttttaag
      481 gagaaaggga aaattgggtt atctaagatt acgtttgtcg gttgtagccg atggataatg
      541 gaagaggcca aaaaaggcaa ttggttgaga acagcctgtt ttacctcgat tcctaacccg
      601 attgacgtga cagcctttaa gcgtatggaa aagcgggtgg cccgtaaacg attcggcctg
      661 ccggaagata agttccttct tctttttgcc gccgctaagc tttcagatac ccggaaggga
      721 gcgatttttt tgatcgaggc ttgcgaaaaa ctaaaagaga aataccaaga tcgcatagaa
      781 atcgtgttga tgggaaatag ctcggaagaa ttgattagcc agtttccttt taaggtgaat
      841 acgctgggat atatatcgga tcaagactct atgatttccg tttatgcctg tgccgatatg
      901 ttcgttattc cttcgttgga ggataactta cccaatacga ttatggagtc gatggcatgc
      961 ggtacgcctt gtgtgggatt tgagacagga gggattccag agatgataga tcatttgaag
     1021 aatgggtatg tagctaaata taaggatact gaagatttag cggagggaat taagtggata
     1081 atagatagcc gggaatcttt acaattaagt gaggcttgca ttcgaaaggt ccatgattgt
     1141 tatcaagaat cggttgtagc ggggaggtat attgatttgt atcggagttt aacttcgcct
     1201 tagaatgaat tctttggata tttcatctat atcaagaata tagttacttt tgtgaaaaat
     1261 ggaagttact atatagtata ggaaggaatg ctatgagatg aaagagtatt tatcaaatgt
     1321 tttagagata ttggaagaaa aaggcgtttt gaacgaatcg tatgatctgg agttcaaaag
     1381 tgcgaagggg gggcttcctc ggtctctttg ggagtcttat tctgcgtttg ctaattccga
     1441 gggaggtaca attattcttg gcgtttccga aaaagataat tattgttatt tggatggttt
     1501 aggagaggat gttgtgcgca agtggcttga tgatttttgg aatcagataa acaataaaga
     1561 aaaagtgagc gttaaccttt tgacggctaa ggatgttcgt atagaaaagg tgaaagatga
     1621 tattaatgta ttaatcataa gggtgcctcc cgcaagtttt cgttatcgtc cggtttatat
     1681 aggaacggat atgttaaaag gaacttatag gcgagatcat actggagact ataggtgcat
     1741 gccagaggaa gtaaagcgaa tgttggcaga ttccttgcct gataaacccg attctcttgt
     1801 gttggaacat tcgacgatag aggacttgga tttgccaaca ttagatcaat atcgaaatat
     1861 tcttcgaagt gttaaaccca tgcatccctt tttgacactt gataatcttc cttttttgca
     1921 gaggttggga gcttggaaag taaatcgagc gacaggaact tatggtttaa ctgccgcagg
     1981 attattgatg ttcggaaaaa cacaatcaat acaagaattt ttcccggact atcatgtcga
     2041 ttaccaagag atatccaatc aagggagtcg ctggatagac cgtatatatc cagatggtac
     2101 atgggaggct aatctttttc aattttttca tagggtatgg cctaaattaa gtttttcttt
     2161 gcccaaacca tttttattgg agaatgggag gagacgtgat gaaggtgcta tccatgaagc
     2221 tttgcgtgag gcttttgcaa acagtattat tcatgcggat tatagggggc agggaggaat
     2281 tgttataaag aaatatccgg atcgattcct gttcgtgaat ccgggttata tgttagttcc
     2341 tttggaacag tattataaag gaggatgtag tgtcccgagg aatactacga tacaaaccat
     2401 gttctcttta ttaggttatg gtgaaaaagc agggtcgggt agtcttcgga taatgtcggc
     2461 ttgggctagt gcgcattgga gaaaaccgtt tatatctatg accaatagac cggatcgtgt
     2521 ttgtctagat ttaaaaatgg aagtattgtt gcctaaggat agtttggagc acttagaata
     2581 tatatttggg aaggatgttc gtaatatgta tggggatgct ttggttatat tgtctactgc
     2641 tgagatagaa ggggttgtct caaatcttcg attacagggt ttacttaata aacattcctc
     2701 ggagatatct attatgttaa aagatttatg ttcgcaagga tatttaaatc cagagaataa
     2761 gggacgttgg acttcttatc atttgaataa gggaatagga cttaaacaag gaagtttatt
     2821 tgagaacttg gatggacacc ttaatgaaaa gatggacacc tcggataaga aagatggaca
     2881 ccttaatgaa aagatggaca cctcggacaa gaaagatgga caccttggca gaaatatgca
     2941 agaaattaaa agctcagaat taaagtctta tattgtagaa atttgctcaa gtaggtattt
     3001 aacaatcgag gagatcgcgg taaaaacccg acgtacttca aaatatctga agaataagat
     3061 agtatctcaa ttattgaaag atgggctttt agaacgttta tatcctacta ctccaaatca
     3121 tcctaatcaa gcatataaaa agaaacaaca atgaatcagc aacctacatt ttcgatcata
     3181 acgatcacct ataatgcgga gcgatggttg gagcgtacga tattgagcgt acttagccag
     3241 tcgtatccgg atatcgagta tatattgatt gacggagcgt cgaaggataa gaccgtagag
     3301 atcatcaagc aatatgagtc cggtatctct tcttggataa gcgaacctga taaaggcttg
     3361 tatgatgcca tgaataaggg attgaagctg gctacggggg actatgtgtg gttcttgaat
     3421 gcgggtgata cactttatac cgcagatacc gtgcaaagaa ttgtggcgtc tttgaaaaag
     3481 aaagtatctt tgccagacgt gatttacgga gagacccgga tcgttgacgc agagggtaga
     3541 tcattaggga tgcgcagatt gaaagcaccg gagaaactga attggaagag cttccggatg
     3601 ggaatgttgg tttgtcacca gtcgtttata tcaaaacggg agatcgctcc gttatataat
     3661 acggaatacc gtttgacggc ggattatgat tggtgtatcc aatgtctgag acgatcgaaa
     3721 agaatacata atacacgttt gatcctgtct aattttttgg aggaagggtt aagtagtgtg
     3781 aaccggaaag cttccttaaa ggagcgatat gaggtcatgt gtaagtatta tggcaaggtg
     3841 tcgacgattc tgttgcatgg ttggttcgcc gtgagattct attttgccaa atggtttaaa
     3901 ggtagagtat aaacaataaa ttatagataa gttttatgcg gagtataatg agtaaatggg
     3961 gaaaacatat cgcagcgata gccgtattct tggtattgac agtgatttat ttttctccgg
     4021 ccgtatttga gggtaaggta gtccggcaag gggatacgga aaaggctatc ggtatgggga
     4081 atagccagat ggatgaatat gagaagacgg cccaaccggg agaattcagc gcatggtctg
     4141 atgctatgtt tggcggaatg ccttatgtgt cgggatatgg caatccagct ccacggtttc
     4201 ccggatatct tttagtggag aagcctttaa aagcgttggg atatatggat gcggggatgg
     4261 tgtttaccgg attcgtttgt ttctatatct tgatgtgtgt catgggcgta aattggtggt
     4321 tggcgatcgc tggtgccatc gctttcgctt tagcgtctta taatctgatc attatagagg
     4381 ctggccatgt cacgaaagcg tatgtaatcg cttatatgcc attaacgttg gcgggtatgg
     4441 ccctgttgtt caagcgtaag tatttatggg gggcggtcgt gttcttgttg ggtgtcgctt
     4501 tttctatcgc gaatacgcac ctgcaaatca cttattattt attattactt tgcttcttcg
     4561 tttatttggg atatttgttc aataaactga aggaaaaagc ttataaagaa ctgggtacgg
     4621 taaccgctat tatggctgga tgcgtgatat tggcggtgtt gccgaatgcc cagaatatgt
     4681 atgctcaatg ggatttggga cagaactcta tccgtggggc tacggaatta acgacaacga
     4741 ccccttcggg cgagaagatc tcttccggct tggacaagga ttatgcgttc gcttggagct
     4801 atggaaaagg ggagttgttg accttgttgg ttccgaatgc ctatggtgga agttcgggtg
     4861 gaatgctagg cccggattct gagttatata aggaattaag ggcgaaaggc gttcaagtcg
     4921 gaaaagaggt acaggctcct acctattggg gagagaagac atttacttcc gggccggttt
     4981 atttcggggc attggtctgc ttcttgtttg ttctgggaat gttcgtgatc cggaatccga
     5041 tgaaatggtg gttattcgga ggttctgtct ttttgatatt gctggcattg ggacgtaatt
     5101 ttgatagctt caatgacttt atgttccatt acttgccgat gtataataag ttccgtaccg
     5161 tggagatggc attggttatt ccgggtatgg tatttcctat tatcgctata tggggattga
     5221 aagaggtgct atcggagacc gtgagcgatg ccttgttgaa gagaggattg atcgctgctt
     5281 tggctatcac gggggggctt tctttaatcc tttggttgat gccgagtatg ctgttggatt
     5341 tccgttcttc tttcgacgct caatatcagt tgccggattg gtattacaac gccttgttaa
     5401 tggatcgtgc ttccttggct tcggcggatg cgttgcgctc tttggtcttt atcttattag
     5461 gggcggcttt gttgttctgg ttctatacct cgaaagatcg gaaaaaggtg gcgacattcg
     5521 tagggattgg tgttgcggtc ttgatgttgg ttgacttatg gacggtggat aaacggtatt
     5581 tgaacgatag taactttatc cgtcagaaac ctacagaggt atataaagag acggtagccg
     5641 atcaagaaat catgaaggat aaggaccttt cttatcgtgt cttgaatttg aataatcctt
     5701 tcttggagac aacgacctcg tactatcacc attccatcgg tggttattac gccgcgaagc
     5761 tgagacggta ccaagaactg atcgaccacc gtctgcaagg agagcttaac tcggttatcg
     5821 gggctttcca gaaagcgcag accgcggagg atttgatggg ggcgttcgct gcttgcccgt
     5881 ccttgaatat gctaaataca cgttatatta tctataatcc ggagcaaccg cctttgagga
     5941 atccgtttgc tttcggcaac gcttggtttg tggataaagt ggaggtcgtg gagaatgcgg
     6001 atgcggaaat agcggcgttg aatacgatta atccgttaac gacggcggtt gtcgataaac
     6061 gtttcgctga tgaggtgaaa ggtttcacgc ctcaattgga ctctaccgct acgataacat
     6121 tggatagtta tcgccctaat aaattagttt atacgacgaa gacgaattct gagcaattag
     6181 cggtattctc tgagatctat tatcaaccgg gatgggaggt aactattgat ggtaagcccg
     6241 cttcgcattt ccgggcggat tggatattac gagctatgtt agttcctgcg ggagagcatc
     6301 agatcgtatt tgagtttaga ccgcaaggtt atattacggc ggcttatatt acctctttca
     6361 gttcgttgat tatcttgttg ttattgattg gtgcggtagg atattcggtt tggaaagcta
     6421 gaaagcaaaa agagatataa attccggttg gttgtagaga cggggcacac cccgtctcta
     6481 caactagatg aaaccgctat tgataaaatc gagcagtttt ctcgttaggg tttcccacga
     6541 gagagctgct ttttctttgg atatgtttgc agggatggtg gcttgctgtg agggggtgaa
     6601 aagttcctcg ataccttggg cgagggccgt tgcggatatc tcaggcacta cgatgcctgt
     6661 acccggcttt tcgatgctgt tcttgaaatc gcctacggga gtacttaaca taggtaaatc
     6721 gtaattgtag gctacagata cgacaccact ttgagtggcg gagcgatagg ggagtactaa
     6781 ggcatccgcc gctgagaaat aaaaggggat ttcctcgtcg ctgatatatt cacagtggac
     6841 gaatatacgt tcttttgccg gagatgcatc gatcagagcc tgatacttct cgaaactacc
     6901 gtaacattcg ccggctataa tgagatggta atcctcgtta agctgtccca tcgcttctat
     6961 cagcaggtct aatcctttat aatcccgtat cagtccaaag aatagaagat tctttttgga
     7021 cggatggatt cctaatttcc ggcatgcctc gttcttgttg atcttactcc cgaaatgatt
     7081 ataaagcggg tgtgggtttt ggatatattt agcgcccggg taaagtttcc gcaaatcata
     7141 ccgcacgtta tcgctcatca cgataaagcc atggcattgc ttgaaaagta acgaagctaa
     7201 aggcttgtcg aagaaacgca gctcatgggg aatcgcgttg tggataaggg tgattacctt
     7261 acaatgcttt ttcatccggt tcgctacgtg ggcgtatccg ggaacgaaaa aggacatcca
     7321 gtaagagata atcagtacgt ccggcgcata ggaacgaatg gcgtttacgg tactgaaata
     7381 actaaccggg ttgacgctat ctaatactcg cacgctctcg atttcgatcg cacggtctcc
     7441 cgcttctacg tattgagtct tgccgggaaa taagatatcc ggataaagac gtttgaagtt
     7501 gaaagccttt acttcatgac cttcttttac taattccgta tagagcatcc cgctgaattg
     7561 ggcgataccg ccacgatagg gataaatggg ggagagaata gcgaaacgca tggtaattga
     7621 aaattaagaa ttgaaaattg aaaattaaga atcgagaact acaggagctg tcctcccttc
     7681 attttcaatt ctcaactttc aattttcaat taattagtat ctgtaatgat cggccttgta
     7741 cggtccttct accggtacgc cgatataatc agcttgcttt tgtgataatg tagataattt
     7801 cacgccgata cgttccaagt gtaggcgggc aacttcctca tccaagcgtt tcggtaagcg
     7861 gtatacacct acctcataag ccatttgcca taagtccatt tgggcaagca cttggttcgt
     7921 gaacgagtta ctcattacga atgacgggtg tcccgtagcg caacctaagt ttaccaagcg
     7981 tccctctgcc aataagaaga tggagtttcc gttcgggaac gtatatttgt ccacttgagg
     8041 cttgatattc gtgtgcttga tattcggata gttgacaagc ttatccacct gtatctcgtt
     8101 gtcgaagtga ccgatgttac atacgatcgc ttgatctttc atctgtgtca tatgctcgat
     8161 cgtgatgata tcgcagtttc cggtggttgt aacgaagatg ttaccctctt tcacggcctc
     8221 ttccatggtc gtaacctcga aaccttccat agcggcttgc agggcgcaga tcggatcgat
     8281 ctcggtcacg agtacacggg ccccgtaaga gcgcatggag tgagagcagc ctttacctac
     8341 gtcaccatat ccggcaacga ctaccacctt gccggcgatc attacgtccg tagcccgctt
     8401 gatgccgtcc gccaaagact cacggcaacc gtataggtta tcgaacttgg atttcgtcac
     8461 ggagtcatta acattgatag ccggaaccag caactcacct ttctccatca tctgatacag
     8521 acggtgaacg ccggtggtcg tctcttccga tacccctttc atctcggcta ccgtacggtg
     8581 ccaacggccg ttatcttctt gaaggatacg atttaatgta tctagaatta cctgttcctc
     8641 gtgattcccg cctttgcggt tgatggtctc cgcatcgttt tccgcacgat agcccatgtg
     8701 aatcagcaag gaagcgtcgc cgccatcgtc aacaatcatg tgagggcctt taccttccgg
     8761 aaaacgaagc gccatgtccg tacaccacca atattcttcc agcgtctcgc ctttccaagc
     8821 gaataccggt acgccatcag ctgcgatagc cgctgccgca tggtcctgtg tggagaagat
     8881 gttacagcta gcccagcgaa cgtccgctcc caacgcaact aatgtttcga ttaacaccgc
     8941 cgtctgaata gtcatatgca gtgagccggt gatacgtgcg cctttcaagg gtttctgatc
     9001 ggcgtatttc tggcgtagcg ccattaatcc cggcatttcg tgttcggcga tctcgatctc
     9061 tttgcgaccg aattcagcca aactcatatc tgccacttta taaggcagat tagttggaaa
     9121 taattgtgac ataaattaat actataaatg gttgagacgc aaaggtacga aaaagcgttg
     9181 atagtaggtg ttctttatct atgaatttcc atctagggca gaggcttgct gagaggtacg
     9241 gtgggttcgt tactgcaacc cgcattgcag taacactgca acgccgttgc agtattgggt
     9301 tctctgtagt tttgcgattt aatgaatact gaaggctcca tctaccaata gcgcatggcc
     9361 atctacgaag ctcgcttgcg ggctgcatag ccaaagtacg gcgttggcga tctcttccgg
     9421 tttaccgagc cgccctgcgg gaatgtcgca caccagctcc ttctccaagg aagggtcacg
     9481 ccgcattaag tcttccgcca tcggcgtacg gataacgccc ggacatacgg cattgatgcg
     9541 gatgttcttt gccgcatagt cgatagcggc ggtacgtgtc agtccgataa cggcatgctt
     9601 acaggctatg taggccgctt gccccggaaa tcccgtgact ccgccttgcg atgaggtgtt
     9661 gacgatggcg ccgccgcctt gtttcagcat ttgcaggatc tcataacgca tgcagttcca
     9721 gacacctttc aaatccacag ccacggtacg gtcgaattca tcgtcggtga tttccgccat
     9781 tgggcgttgc ggtgtttgta tgcccgcgtt gttaagagct gcgtccagtc ttccgtaggt
     9841 aactacggtc cagtcgatca tctcctttac ggcttgcgtg tttgatacgt cgcaccgata
     9901 cgctacggcc ttatgtccct cggctactaa tttctctgcc tgttctcccg gcttacggat
     9961 gtctgccaat acggttatgt atccagcctt ggcgaaggct tcggcgcaag cgagtccgat
    10021 acccatcgct gaaccggtta ctaaagctac tttctcttcc attgtctttg tcatgatcat
    10081 ttgatttaca ttttgttatt atttatgttg cgaagataag gagggagtgg tatagaggct
    10141 ttgttatgtg gttcaaatag ctttgttgtg tgggccatta taaatattat atatcctcgg
    10201 ttggcggtac gccatacgct atcttataga ttttcgagaa atgggaaagg ttcttgaagc
    10261 ctacctcgaa acaaatctcc gagaccttac gccccccctt acgtatcagc ccatgtgcgg
    10321 cttcaaggcg gcgtcggatg agccattccc ggggcgagag agcgctacat ttcttgaaat
    10381 cacgtttaaa tgtggagaga ctgcgtcccg tatagttggc gatttcttcc atggaaatat
    10441 cgttcatata attccgctcc ataaattcca gtatgtctat cttccatgga tcggtaaaat
    10501 cgaagataga ggcatataga ttcttgtcgg tattgagcaa cacatagacg ccctcgacca
    10561 tttttagttg aagcaattcg tctgtcggtt ggatcttgga attgaaataa ggggtcatcg
    10621 actcaaacaa gcttacgata tcgggacggt tggacggtag cttgtaaagg cttacctgat
    10681 ctcgcttggc gtctttaggg agagtatttc gatctaattt gctgtaaaag tcgcatagga
    10741 acttcatggt gaacatcaag aagatcgcct tgaactgctc gccattccat gcttgtttcg
    10801 tcatctgtac gctgaagtcc ttgcggatga aagcgcattc tcctttatgt aaccgggtga
    10861 tttggccttt ctcgtcgatt accatctctc cggagtatac atacaccaac acgtgcgaat
    10921 gattccggtg caggcagctc tttccgccat cgaaatacat cgctaaaaat aaatccgagt
    10981 aacgcagtgt gttgatcccg tccatcgttc tttaggaaaa tgggcgacac gggaagatcg
    11041 tgccgcccat tatgaggatt ttaaagtaac tgttaactgt ccactaaatc gttaggccgg
    11101 cgtgatacct tgctcttgca atagtttcag cccgaggtct ttcaacttga acttctgtat
    11161 ctttccgctt ccggtcatcg ggaaggtatc gacgaagaag atgtatttcg ggatcttatg
    11221 ccgggcgatc tttccgcggc agaagtcttt cacctcttcc tccgtagccg tcacgccatc
    11281 gtgaaggatg ataaaggcac ccacttcctc tccatatttc ttggaaggaa cagcagctac
    11341 ttgcacgtct ttcacgccgg ggaaatgata gaggaactcc tccagctcac ggggatagat
    11401 attctcgccc ccgcggataa tcatgtcctt gatacggccg gtgatccgat agttgccgtt
    11461 ctcgtctttc acgcctaagt cgccggaatg caggaagcca tccttgtcga tcgcctcatt
    11521 ggtggcggct tcgtttttat agtaaccttt catgttatta taaccgcggt tacacatctc
    11581 accctgtacg ccgacggggc attcttcgcc ggtctccgga tcgataaccc gtacctcggt
    11641 aaattcgaac tcatggccta cagtattata acgcacctcg gccggatctt cgatacggga
    11701 gtgggtcata cccggtgagg tctctgtcaa tccatacacg ctggttacac gcatatgcat
    11761 cttctcgtcc acggttttca tgagttcaac cgggcaaaga gaacctgcca taataccggt
    11821 acgtaacgac gtgaggtcga acatctcgaa catcgggtgg ttcagctcgg caatgaacat
    11881 ggtaggcacg ccgtacacgg ccgtgcaacg ctctttatgt atagaagcta ataccaatag
    11941 cggatcgaat ttctcgacca tcacttgcgt acatccatgc gtcaatacgt tcatggaagc
    12001 taataccaca ccaaagcaat gaaagagagg tacgcagcaa caaagcttat cgtcggcggt
    12061 gaatttcata tgctcacccg tcaagaaacc gttgttggcg atgttgtagt gagtcaacat
    12121 gacccctttc gggaagccgg tcgtaccgga agtatattgc atattgacaa cgtcgtggca
    12181 atttactctc gctttggcag cctctaaggt ctcatccttg atattttgtc cgaggagcaa
    12241 catctcgggc gtattgtaca tacccctgta tttctcctgt ccgatatata ctacatttct
    12301 caagcgtggg aaacgcttgc ttttcaaata cccccgttga gaggtcttca attccggcaa
    12361 catggtatag accatgtcca cgtaacttcc atcaaacacg ccgtccgtga tacacatcgt
    12421 atggatatcg gcgttctcaa ccagatattc cagttcgctt tgtttatagt tggtgttgat
    12481 cgtgaccagt acggcaccga tcttggctcc ggcatataag aaagtcagcc aatccggtac
    12541 gtttgtcgcc catacgccga catgtgtgcc atgagtgata ccgatcgcca gcatgccttt
    12601 cgccatgtcg tccacacgct tgttgaattc gctccaagtg aaacgtaagt cacggtccga
    12661 ataaacgata tattccttgt ccggtgtagt ctcggcccaa tgttccagcc attggccaag
    12721 ggttctgtta tgtaattcca taaaacgccg gatttaataa ggtgtataga caactcctag
    12781 gattcgggcc ttgttgtcgg ctgccgcatg tacatgatgc gccacgatag aatcataata
    12841 gatgctatcg ccttcctcta ggatataggt gttctttccg taattgatct ctacgacgcc
    12901 attcaatacg tagataaact cctctccctc atgcgtggac aggatgaaat cctcgccttc
    12961 ctcggaggga gcgatctcga tcaagaaggg ttccatatgg cggccggact tatcttgcga
    13021 gagcgagtgg taatccatat gcttgtgccc ttgtgtcgcg ttgttcgtga acccgatacc
    13081 atcggcctcg ctgtcctttt tgcggcatac gaccgggcct agctccgctt ggtcatccaa
    13141 gaatgtaccc aaacgtaccc ctaatacccg tgctattttg ataagagggg ccaaagatgg
    13201 aaaatccaag ttaccctcga tacgttcgat ctgttcgata cctaacccgg agcgttcggc
    13261 tacctcctcg atagagagtt gtttcgattc ccggatattt ttaattttcg cgcctataat
    13321 tttgttgttt cccatgtgta tgatttgtta tttatagtcc tgtaatgttt gataatttga
    13381 tactaaacgg cgcaaattta cattaatatt ttattatatc taggattaag acaaataaaa
    13441 agggcaatac ccatttggga ttgccctttt taatattttc gagtaagctt tttcttactt
    13501 tctgatacca agttctttga tgatagcgcg gtatctctcg atgtcagtct tgatcagata
    13561 gtccaataaa cgacgacgtt tacctaccaa catcttcaat gatctttccg tagcgtaatc
    13621 tttgtgattc actttcaagt gctctgtcaa gtgagagata cggaatgtga acaatgcgat
    13681 ttggctctca gcagaacctg tgttagttgc tgatttgcca tacttttcaa ataattcttt
    13741 tttcttcgct gaatctaaat acatgattct ttttacttta ataaattaat actatgttat
    13801 ctaagcggtc gcaaaggtag acattccttt ttgatttgca atagattcta ctatcttttt
    13861 tgtgttttga agcatgaatg tcatatatat atcgtaaaaa tatcgtattt ttgcagccaa
    13921 taaattagtc ttcaatgcaa aagatcagaa acattgcgat tatcgcgcac gtagaccacg
    13981 gcaaaacgac gctcgtggat aagatgttat tagccggtaa gcttttccgt gaaggacagg
    14041 cagaaccgga tcagttcatg gataacaatg atctggaacg ggaacgaggt atcacgattc
    14101 ttgccaagaa cgtgtctatc aattataagg gatataagat caatattatt gacactccgg
    14161 gccacgccga ctttggtggc gaggtggagc gtgtcttgaa tatggcggat ggttgtttgc
    14221 tattggtaga cgcctttgag gggcctatgc cgcagactcg ttttgttttg caaaaagcga
    14281 ttcaactggg tttgaagccg atcgtggtaa ttaataaggt ggataagccg aattgccgcc
    14341 cgtcggaagt gcaggaaatg gtattcgact tgatgtttag tctggatgct accgaggagc
    14401 agcttgactt ccctactatt tatggttccg ccaagcaggg ctggatgtcc gaggattgga
    14461 aggagccgaa agaggatatc gcggctgtgc ttgatgcgat catcaagtat atccccgaac
    14521 caaagatgtt ggagggtact ccgcagatgt tgattacttc tttggattat tctaagtatg
    14581 taggtcgtat cgccgtagga cgtgtacacc gtggcgagtt gaaagagggc caagatgtca
    14641 tgctttgtaa gcgtgatggt agtatggtga aatcgaggat caaggaagtg gatgtattcg
    14701 agggcttggg acgtacgaaa gttgattccg tgcagtccgg ggatatttgc gctattatcg
    14761 gtatcgatgg tttcgagatc ggtgagacta tcgccgacgt gaacgagccg gagccattgc
    14821 caacgatcgc tatcgacgag cctacgatgt ctatgctttt cacgatcaac aattctccgt
    14881 tctttggtaa ggatggtaag tttgttactt cccgtcatat ttttgaccgt ttgcagaaag
    14941 aattggataa gaacttggct ttacgcgtag ttcctactga ttccgctgat tcttggttgg
    15001 tatatggccg tggcgtgctt cacttgtctg tattgatcga gacgatgcgt cgtgagggat
    15061 acgagttgca ggtaggtcag cctcaggtta tcatcaagga gatcgatggt gagaaatgtg
    15121 agccggtaga gcaattgacg gtgaatcttc cggaggaatg ctctagccgt attatcgata
    15181 tggtaacgaa gcgtaagggc gagatgacca tgatggaaag caagaatggt cgtatgcact
    15241 tagaattcac gattccttcc cgtggtatta tcggtttgaa caacgccgta ttgaccgcct
    15301 ctgccggtga ggctatcatg gcacaccgtt tcttggaata tcaaccgtgg aagggtgata
    15361 tcgaacgacg tatgaatggt tcgattatcg ctatggagac aggtcaggct ttcgcttatg
    15421 ccctgaataa cttgcaatcc cgcggacgtt tcttcatcgc cccgggcgag gaggtttacg
    15481 ctggacaggt ggttggtgag cataccaagg acaatgactt ggtggtaaat gttaccaaat
    15541 ccaagaagtt gacgaatatg cgtgcctctg gttcggacga caaagtttcc ttggctcctc
    15601 ctatcgtatt cagcctagag gatgcgcttg agtacatcaa gggcgatgag tacgtagaga
    15661 tcaccccgaa taatatgcgt atgcgtaaga tcatcttgga tgagacagag cgtaagcgcc
    15721 aaggtagata atatattctt ctattaatag atacaaaaaa cggcgggcct ttaaaaagct
    15781 cgccgttttt tatatgatgt taggatttta gagatccttc aatgagtgtg tatccttcat
    15841 tctttatttt ccggatcttt cttctcttca tccggagtgg taaattgtat cactaacgat
    15901 tcatctttag gagtctcata ccaatctcca tgtgcctttc ggtaatcttg gtcaaaatta
    15961 taagcttcgt cgatgctttt attctctata caccaacgga aaggttgact ttccgaataa
    16021 ggaatatcca atacatatgg gtatagatcc gtattcttga cgtttttact taccggtccc
    16081 ttcccgttat caatgtaagg catgatcagc tgagtcgcac tatatgttaa tgtctttgta
    16141 atcccacttt ccggttcctt gtcgaatttt ctcacattga catatccatt gacatcggag
    16201 aaaaagggag ttagtccatt ggcgtcctta aatccaaatt ggttgtggaa tgtacagcct
    16261 ttagccagta actgggcata aacatctgcg gtactcttat cggtatatgc tgtgatgcta
    16321 taatatatga cagcgtcatt gaaatcgaaa tcgccttggt ttggataatt atcttcgaac
    16381 aggaggaatc ctttcttgtt cgtttgcgat tctatgacgg gaggggttac cggctctgcc
    16441 ggctcgatgg caacgggatt actttcgatt agacaaagca tatcgttgta gtctccatca
    16501 taggccctat agtttgggca gcgattttcc attcccagta catttccttc aaaatcacct
    16561 tcttgaatgt ggtgaatgaa gccatttgct acgtttttct ctattttgaa agaggaatta
    16621 ccatatttta aggtatggcc tacgtaatta tgggagaatg tcccattatc tggtacttta
    16681 ttgttatccg gcccatttaa tgccggagtg gagaactgtg gacggtctgt gcctcgatat
    16741 acgaagccga cgttgagccc cttgtcgaat cttcccaagg gtattcgggt atattctcct
    16801 gcttgggcct ttggctgttc ttctttggag tagaatatat aattatcgcc ttggttgatc
    16861 gtattgaagt cagtgacttg gatagcacca ttagtttttc catagaaggt gcagtcatct
    16921 aaagtaaggt tctccatctt ctcggaggga tatgtataga accaaatttt accatgcata
    16981 ttactgttgc ctttggacat tcctccatcg cttatatagg ttagccaaat atccgctttc
    17041 tcaaagctac tggtaaaaac ggtttccgtg atttttagat cagagcatct atataaatcc
    17101 tcgcttttta cattgtatgc tttttctgga aagtatttgt tattgatcag atgaaggact
    17161 tcatcactga tcgcatttgt agcccgtaag ctgcttttgg tatcgcttcc gatcgtgatg
    17221 tcctttacat cgctctcgat aagttcccca tcccctctta ggatatagag tttctttacg
    17281 tgtttaggta cttccagggc catatggatc ggagttttac caattaaata aggatctttg
    17341 actaaagagc cttcctcata aggatattca taataaatag aatatagggt cccttcatgc
    17401 tgagaagata tgctaacctg tatgttctcg aaattctcga actgggctat gtaatcttct
    17461 ttttctttgg taggttcttg aggatctacc gaggggtctt ctccttgata aatgtcatgc
    17521 ttaacgcatg attccataag gaagagcaga caaaataccc acaccatttg tttccagatt
    17581 tgtgatctca taatttcttt accctatttg attaatattt acaacaactt tattgaattt
    17641 tgcaaatcta cggatttatt ttataaaaaa gtcattgata atcaatattt gttttgaagt
    17701 gttgcaatat tctgaaatat aggcttgagt gggtggaata taaaaaaacc ccatccaaaa
    17761 ggatgaggtc tttttcttat ttagaaagaa tattttctaa ttattttact aaagctgaga
    17821 agtcagagtt agtcgcatat ttagcgaact ctaagtcgat agcagcttcc ttagccaagc
    17881 tcttgtcagc agcgatagcg gccttcaagt tgcttactac accgttagcg tcgtttgtac
    17941 gagcagcaac aacagccttc aagtaagagg tgatagcatc aggtttagca acaccgttca
    18001 aagtctgaga agccttgctg taatccttaa ccaagatctg agccaaagca gcgttgttag
    18061 tcttaacaga accgaaagag ttaacagcct tagcatattc gccttgctct aagtaaagaa
    18121 cgccaagagc ctcgctcaat tcgtttacgc cggcagcgtt accgaacaat tgttgagcct
    18181 tagcttggtc acccttcgtt aatgcgatca aacctaagtt catgttagcg gaagcgttat
    18241 tcttaataga gttagacttg ttgaacattt gctcagcctt agccaaatca ccagccttga
    18301 atgccatcat accgatgttg ttccaagtac ggtagcagtt agggtacaat tcagaagctt
    18361 ttgtatagat agccatcttc tcaccgtcgt tgttagtcaa tgtagcggcg taaaggattt
    18421 cctcgatatt caactcagaa ggattgctct ttgccaaagc gctgatctcg tcgtcagact
    18481 taccgatgat ctcgatgtta gcagtcaaac gagaacgacg taattgcgga aggatagtct
    18541 cagccaagtc agagtaaaca gcggagatat tcttgatttc tttctctctt gtctcaggat
    18601 cttggtacat agagatcaca cgcaatacta agtctttatc ttgcaagtta gaagcagaaa
    18661 ctaattcctt gaagccttcc cagtcttgag ctgtgtaacg agcgtcaacc ggagcgtcaa
    18721 ccttcatctt cttcaattcc ttgttcaaat atttcgtagt gtttccttca cgattctcag
    18781 ccaacgtgtt gttcaatttg aaaccaccat caggagaagc gtaagcgctg atctcgatag
    18841 ctacattctg gttcggagcc tcgtcagcgt tcttaacaag atctttccat tctttgatag
    18901 cgtcagaatt caattcttta gcgcgaaggt tagcttgttg gatcaagaac atgatgttag
    18961 cgtcatgagc ctctttgata atacgttgga atttatcagc tgcgatagct gctgtagcgg
    19021 tagctgcgtc tgccaattcg gaagtagcga taacgccttc accgatcttt acgtctggca
    19081 atttaacagt cttgtttttg atcttcgcgt cgaaagtcaa atacaattct gattttttca
    19141 tctcgggttt gtaagtgaaa gaagacttca tagttacgtt agcgccttct ttttgaggga
    19201 ttacttggtt gttacctttt actttctcac cttggtaagt gtaagaagtg ccccaagctt
    19261 cgccaccctg gtaacgcaat accggagtta cagttacaac agctttcttg ttgaaccatt
    19321 tagcggggaa agtcgcgttg atcgttacag gaactttgcc tccgatagcc tctagcggct
    19381 gcggctctgc tttaatgtac tgttctgcca acggtttcaa cttgtttgaa caagaagaaa
    19441 gagttaaaat ggctgccaat acgaagaatg gcaataaaaa ctttttgttc ataatcttga
    19501 tgtaagttta aaatgttact atgttaatat attcacttcc aaattatccc ttagccatta
    19561 tcgtgcaaaa ctaaagtatt tttttgttat ggatagcaaa gaagcgataa aatcttttta
    19621 attaatactt attaatgaat cctaggcttg ttttatacat aaaatatggg tagaattatt
    19681 gaaaaaatat ggctgtgtac ctcttgccat tcttttcaat ggatggtttc ccagaactct
    19741 tattgtatat tttttgatta aaatataatc ttttgtgtat aatgctcctc gccatagtgc
    19801 acggttagaa agtagactcc agatgttaat tttaggaaat ggagtgtagc ttgcctgtcc
    19861 gtgatctctc cgttttccga cacttttcct tgtgccgagt gcaatgtata agtcgctttc
    19921 tctattccat ccggcaaaac aaggtgtacc atgcctttct ccggaccgag atgaatgagt
    19981 acctgctcgt tcgcctcgag cttttcgttg ctgacggggt taccnnnnnn nnnnnnnnnn
    20041 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    20101 nnnnnnnnnn nnnnnnnnnn nnnnttgttc ccgaacaaat acgctttttc agacccggga
    20161 tagagcgtac attcggcgtt ttcttgatta ccggagtcat agatgttgct caaccggaaa
    20221 caaggggttg atttatacgg atcaagtccc tcgcaaacct tggtctcgtc atcggacggg
    20281 tttagccaat atttgagctg tctctcgggg gtatcgatcg cgtcccaggg tttcttcaaa
    20341 gagaagaagt aatcattctt cggactattc tcactggact gcccgccgga taacgctccg
    20401 ataatctctc cgtcggcatt gaataaagga gatccggagg aaccgctggc cgtataacct
    20461 acttcccaag tcttgacatg taaatgagcg ttctcgtaaa aaatcatgtt tggatctgtc
    20521 aaggtaaagg gagccagatc ctcatcggat atactgattc gctttaccga gtattgggga
    20581 tgttggatgc acgtataggg ggcaggtcct acctcttgtg cgttccagcc cgcgtaataa
    20641 ggcctgtaat aaaccggagg tgtggcggta agttccaaca aggccatgtc tgccatttca
    20701 ttaaccgcct tgaagtaagt ggatgcggta gacatctctt ccgttcccct taggatcggg
    20761 tcgcagaaag ggctgttgaa gttgaaaaag cagacgatac ttccggctat tttctcataa
    20821 tcggggtttt tcatcgtgaa ttgcttgttt aggcaatggg aggcggtgag tagataaggc
    20881 tttccgtcat tgtccgtatt atttatcagt gtgcccgtgc accctacact tccgtctatg
    20941 atcaggagaa cgacgctttg cccccattgg gcgtaatcgt ttgtcccatc ttgatagcaa
    21001 gctaacggtg gaattttacc gatcagtgag gtgttgtctc ccggttctaa cccccgcaag
    21061 ctccggtagc catggttgac ttccccgacg gtcagtcttc cttgaaaaga ggcgttggcc
    21121 ggttcttgat attctatgat caggcgatcc ccttggatag gagagaccgg caataggttt
    21181 aactccgagt tgtttaggtg attgaacgag cctaatatct gtgtctggtc ctcattatat
    21241 aggaagagct gggcgccttc gggcagttca tattccgtga agagcacgtt gatggaaagg
    21301 gccccgggcg agtagatccc gagtctccat acacgtgtcc catccggccc ggtgaaagtt
    21361 acgcccgagt tgtaccgatt gtaatccgtt atgaatttat aggcaaaacg gaaaccgctt
    21421 cttaggtcgc tctcattcag cgagtcgata cgcaattcct cttggacgtc gaatggaggc
    21481 atttctttaa acatctgtcc gtttgtactt cgcatgagcg atagcggaag cgggcggcct
    21541 ccgtggctaa cctgcgcttt cagatttcct tgaaaaccta gcatcgttag caggaataca
    21601 atgtataaag aggtcaactt tttcatatcg ggcaaatata gctatatttc tttaccccat
    21661 gatctatata tcaagttttt tcgctaagtt tgccaatcga aaagtacgga caaacttaaa
    21721 taaaaccaat atataattaa attctaaaga tatggcaaca cctccgtttc actacgagcc
    21781 gatgttccaa aagggaccgg acacaacaga gtattatttg cttacaaaag attatgtttc
    21841 cgtttctgag tttgaaggaa aaccgatctt gaaagtcgct aaagaaggtt tgaccgctat
    21901 ggctaacgcc gctttccgcg acgtatcatt catgcttcgc cgttctcaca acgagcaggt
    21961 cgctaagatc ctaagcgatc cggaagctac ggacaacgat aagtacgtgg ccttgacatt
    22021 ccttcgcaac gctgaggtag cggctaaagg cgtacttcct ttctgccaag ataccggtac
    22081 ggctattatc cacggcgaga aaggacagca ggtctggacc ggttactgcg atgaggaagc
    22141 gctttcctta ggtgtttaca agacctatac ggaagagaac cttcgttact cccagaacgc
    22201 tccgctgaat atgtacgatg aggtaaatac gaaatgtaac ttgccggccc agatcgatat
    22261 cgaggctacg gaaggcatgg agtatgagtt cctttgcgtg acaaagggag gtggttccgc
    22321 caataagact tatttatacc aagagacaaa agcgatcttg aatccgggta cattggttcc
    22381 cttcctcgta gagaagatca agacgttggg tacggccgct tgtcctccgt atcatatcgc
    22441 gatcgtgatt ggcggtactt ccgctgagaa gaatttattg acggtgaagt tggcttctac
    22501 tcgtttctac gatagcttgc ctacgaccgg tagcgagggt ggccgtgctt tccgcgacgt
    22561 ggagttggag aaagaggtat tggccgccgc tcagaatatt ggcttgggcg ctcaattcgg
    22621 cggtaaatat ttggctcacg atgtccgtat catccgtttg cctcgccacg gcgcttcttg
    22681 cccggtaggt ttgggtgtaa gctgctccgc ggaccgtaat attaaatgta agatcaataa
    22741 ggaaggtatc tggatcgaga agttggatag ccatcccggc gaattgattc cggaggaact
    22801 tcgccaagcg ggtgagggcg acgctgtcaa gatcaacttg aaccaaccga tggcggatat
    22861 cttgaaggaa ttggataaat atccggtatc tactcgtttg tcattgaacg gaacgatcat
    22921 cgtgggccgt gatatcgctc acgctaagtt gaaggagcgt ctggatcgtg gcgaggatct
    22981 cccccaatat atcaaggatc atcctattta ttacgcgggc ccggctaaga ctccggcagg
    23041 tatggcttgt ggctctatgg gcccgacgac cgcgggtcgt atggactcat acgttgactt
    23101 gttccagagc catggcggta gcatgatcat gttggcgaag ggtaaccgta gccagcaagt
    23161 tacggacgct tgtaagaacc acggcggttt ctacttagga tctatcggtg gccccgcggc
    23221 tatcttggct cagaacaata tcaagagcat cgagtgcgtg gaatatccgg aattgggtat
    23281 ggaagcgatc tggaagatcg aggtagagaa cttccc
//
LOCUS       DBMDTB010000066        22705 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_771_length_22705_cov_10.638737, whole genome shotgun sequence.
ACCESSION   DBMDTB010000066 DBMDTB010000000
VERSION     DBMDTB010000066.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 22705)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 22705)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22705
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_771_length_22705_cov_10.638737"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..279
                     /locus_tag="ACZPB4_11220"
     CDS             <1..279
                     /locus_tag="ACZPB4_11220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RagB/SusD family nutrient uptake outer membrane
                     protein"
                     /protein_id="HIR1098818.1"
                     /translation="QKLGKQAFIEECWTERLREFPLEFKIWDDCLRTGKFPVISSTEK
                     GKVTYVDLVGAKNASGATFKSSDLLWPISLNEMQRNPSLTQNEGYAVQ"
     gene            complement(1629..3221)
                     /locus_tag="ACZPB4_11225"
     CDS             complement(1629..3221)
                     /locus_tag="ACZPB4_11225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RagB/SusD family nutrient uptake outer membrane
                     protein"
                     /protein_id="HIR1098819.1"
                     /translation="MKKILTTAILCAGLVGFTACDSFLDEDPKSSLTLDTYYKTSADI
                     IGNVNYLYRDGAPDKMGNMTGAYRGSSLSVMNMVTGYFVNEYEGQEVDCSYARQLTRQ
                     DFTQSCCNYLTNDTWKSCYKSINVANAVIKYVDGVEMDNQAQYKAEARFFRALNYFYL
                     VKMFGDVPMVTEPTEDATLVEYPTRTAASEVFNTVIIPDLQFAVENLPNATFAGNSHR
                     VTKYAADMLLADVYMRLGEYANAVTPLKDVINSGKFALATNDNLAEGSAFNKLRTTDD
                     LPEVIYAREYDAAISPNGNIPVHAFNLISPTFFANSSTGNKYSLWVNVYGVSERYLNV
                     YGEKDLRAQMNQFFHRTYTHPVDGTTLDMKMLCNWYWYDETAILETGKGTKDWNFYRY
                     AETLLSAAEAIAQSSGVNAEAAGYLAQVKARANMEGKDVSTIASELQRLGKQAFIEEC
                     WKERLREFPLEMKIWDDCVRTGKFPQISATNKGEVQFVDLIGAKNGSGATFKATDLYW
                     PIPVNEIQRNPNLTQNEGYSAK"
     gene            complement(3248..6424)
                     /locus_tag="ACZPB4_11230"
     CDS             complement(3248..6424)
                     /locus_tag="ACZPB4_11230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SusC/RagA family TonB-linked outer membrane
                     protein"
                     /protein_id="HIR1098820.1"
                     /translation="MTKNESKLLSIQGIAKASAFCLLLSAFSVNAAMAAPAPAGTVDE
                     VMAVQQGKKVTGVVVDGTGEPVIGANVVVKGTTNGTITDFDGNYTIEGVPADGVLVIS
                     YIGYLSQEIPVGNQSAINVTLKEDTQTLDEVVVVGYGTMRKSDVTGSISTAKGEEMLK
                     AQNFSALDNLRGKAAGVNIFSNSSQPGAYGSRVVIRGQATINASSDPLYVVDGVVMEN
                     FYLMNPNDIESMEVLKDASATAIYGARGANGVIMVTTKRGNKEGGTKVSYSGSVSLAH
                     RARKMDTMNAQEWCDAFMQGIENENRWGSDKDGNPFNWSTNRADWFTDRRFFDSNGNP
                     LYDTDWQDEATRTAISHNHQLNVQQGGEKSSMGAFLNYTDNQGIMLNTYSKRLNAKIA
                     YDANPTTWLSTAINLAVNHTWGNSTPEDGGGQDARRTMIEMVPWMPVQYNGKYTSTNT
                     PEGMPMDFEAMSNPVHILKTYKNMNYNTKVFGNAALTFHIIEGLDLKTQFGVDANFKT
                     LHKYMPSDLVNLAYDQHGRAERYHANTLYWQEETYLTYNKTIGEHRINAMAGLSWQER
                     KYDYSRMYTENFTTDFFEDFNMDAGTKPDAPKTYWERWAMNSYFLRFAYTFKDRYSAT
                     ITGRYDGSSKFGKNNKYAFFPSAGLAWNITQEDFMSDQNTISNLKLHTSYGLTGNSEI
                     GVYKSLATVKSETLLLNGTRNSYSYLNRLPNSDLKWEKTAQFDIGFDLGLFNNRITLD
                     ASYYNKKTSDLLLDAPVPHTTGFETVYKNIGSIRNQGLDLMLSTRNIDTKDFTWTTSI
                     NANFNKNKILSLGDNDEDILKNEWVSGASILRVGESVGSFYGYKRLGVYTIEDYEAGN
                     CQKKQIGRAKRSSEREIIGKGVPDWTGSMINTLRYKNWDFTLDLQFVAGVQTLQQFYH
                     STYDRFGQTNGLTNILYDAYNGTNPNSMQQAIWLFNGGHAGQDTLTDSQWVANGSYLR
                     ANLIQLGYTFDSNQLAKTPFSSLRLYLNVNNAFLITAKDFNGYDPESTSQISTSNGSV
                     SPEQFGQNMAFFSYPRARTFTLGVNVIF"
     gene            complement(7155..10043)
                     /locus_tag="ACZPB4_11235"
     CDS             complement(7155..10043)
                     /locus_tag="ACZPB4_11235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004559 - alpha-mannosidase activity
                     [Evidence IEA];
                     GO_process: GO:0006013 - mannose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 38 N-terminal
                     domain-containing protein"
                     /protein_id="HIR1098821.1"
                     /translation="MKKRTYLSAGLALLIGTLSVHASPGLSDVKSRVLPAVYKSKNGL
                     TQKVEISVKHEGEPSTVTIRLGEQSRKEKLVSGDNVFRIEIPEVSTTRQLPLTLTSGK
                     EKEETMVTVKPVRHWQMNMVQHTHTDIGYTRSQMEILAEHLRYIDYALDYCDATDNYP
                     DFAKFRWTCEIAWAVSEYLKCRPAEQIARLKQRVKEGRIELATMYLNFDELPDEQTLA
                     ASLYPIKQFRENGMRAEVAMQDDVNGIGWCFSEYFADAGVKYVNMGTHGHRALICFDK
                     PTVFWWESPSGKKVLTYRAEHYNQGNFFGIHTDDFEQFEERVLAYLDQMEAKNYPYDI
                     LAAQHSGYFTDNAPPSTKSCEMLQKWNEKYEWPKLRTAVASEFFKTVESQYADRIETI
                     RGAWPDWWTDGFGSGAREAAISRVTHSDIIANQAGLSFAKMLGAQLPTDINDRIQDIN
                     KALLFYDEHTFGHSESVRNAYGLETWEQRSLKQSYAWEAYRHSGLLGEATMGILQSFV
                     PKSDVPSIAVFNTLNWSYSGIAKAYVDHQILPKDKAFEIVDTAGNVIPAQAGESRSDG
                     TYWNFYVKDVPALGYAQYYIKVKDAPRPEIQGATELKETHVENPWYAIDFNTRKGTIR
                     KLYDKDLNKQLVTPDAEWEMGEFIYEIIDSRHPMEQYRAPQFLRRRPEKMRFEKYEKG
                     DVWDTYRFRGETVAGREPNNLMVEFRVFNVTKKIEVVYRLRKKAVTDPEAVYIAFPFE
                     VEGGKIHLDVPGGSIEAGVDQIPGSSNDWYTVQNFATARNGESQVVMGSQEIPLMQFG
                     AINTGRYKAGAVPQSTNMYSWPMNNYWVTNFNADQMGEMQWSYFINSSKDNSIEYATK
                     FAWENRIPFLTRVLPAGDKKVEPLQSASIFKIVPENLLLVNMRPVEGENAVMLQLREI
                     GGKPATFSVTSDKINFVKTTVCDVVGDPVSGNPLSFAPWENKFIKLSW"
     gene            complement(10045..11187)
                     /locus_tag="ACZPB4_11240"
     CDS             complement(10045..11187)
                     /locus_tag="ACZPB4_11240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HIR1098822.1"
                     /translation="MRTKSTNSAIFPILFGFFVMGFVDVVGIATNYVKMDFGLSDTLA
                     NLLPMMVFLWFALFSVPTGIWMGRHGRRNTVVAALAITTLAMLIPLFFYDFACILFAF
                     ALLGIGNTILQVSLNPMVARVVNPDKVTSVLTLGQFIKAVSSFLGPIIAGVASSFWGD
                     WKLIFIVYSVTTLLSIIWLITAIPGKEEGEEQEASFASTLALCKDARIRMLFLGILCI
                     VGIDVGLNTTIPKLLMEKLSMPLQEAGLGSSLYFAARTGGSFLGAILLARISSRPFLR
                     GSMLIVILAFVGLLISDSLWSMGVMIVLVGLACSNVFSILFSFALEHRPEQSNEVSAL
                     MIMGVSGGALITPCMGGLADMFGQVAGLMLLLICMLYIGLISIKTR"
     gene            complement(11177..13543)
                     /locus_tag="ACZPB4_11245"
     CDS             complement(11177..13543)
                     /locus_tag="ACZPB4_11245"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HIR1098823.1"
                     /translation="MRKYSMKPVCFLLFLCGVFTSCVTQGKKVQQEELSQYVEPRIGT
                     AHCRWFHFTPGAMPFGMAKPAPSTNGHIGNKSGWEATGYDYRDQSIEGFPCLHEFQIG
                     GIVLMPTTGSLKTIPGAVDDSTGIGYRSRFDRADEIATAGYYSVLLKDYSIRAELTAT
                     PRVAIQRYTFPAGEDSRILFDIGNRQGESGAVRDAEITFTEDGRIEGWVITEPEYVRK
                     YQPGASVPLYFSAVLDKAPVGYGAFNGADIRPDERKATGVGAGLYLTFRTQDQESVTA
                     KVGLSYTSVENARLNRETEAATLTFDEAREISRQTWEEYLGRIRVETPAQEDKVKFYT
                     GLYHALLGRGLASDVNGAYPRNDGSVGQIPLKDGKPIHNLYNTDAAWGAQWNLTQVWA
                     LAYPEYYSDYISSHLLVYKDAGWLADGIANSRYVSGVGTNLLSTIIAGAYQCGIRDFD
                     VNTAYEACLKNELDGENRPLGAGKIDTRYFVEYGYVPHLDKGDGPDEAFMFSASHTLE
                     YAYSAWAVAQWAKQLGKTDDYNRLKDLSKGWERIYDPSCNFVRPKKKDGTFIEDFNPM
                     QVWRGFQEGNAWQYTFYVPHDAKGLVAKVGADVFNHRLDSIFTVSRKLIFSGGTEVGA
                     FAGLQTLYNQGNQPCLHIPWMFNEAGRPSLTQKWVRAILNEFYGTDGIHGYGYGQDED
                     QGQLGAWYVISSLGLFDMKGLTDQAPSFALGSPLFDKITIRLNDRYYKGKEFVIEARN
                     NSKQNDYVQSMNLNGKPLTDTRIPFSEIIQGGHLVLEMGSQPKDGYEN"
     gene            complement(13547..14644)
                     /locus_tag="ACZPB4_11250"
     CDS             complement(13547..14644)
                     /locus_tag="ACZPB4_11250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HIR1098824.1"
                     /translation="MMYTNDNRIVMTLDAGGTNFVFSAIQGGKEIADPVVLPACADCL
                     DKCLGNLVEGFKAIQAGLPEAPVAISFAFPGPADYQAGIIGDLPNFPSFRGGVALGPF
                     LEDIFGIPVFINNDGSLFAYGEALTGVLPEINRRLREAGSTKRYKNLLGVTLGTGFGA
                     GVVIDGELLRGDNAAGGYVWCLRNKKYPEYIVEESVSIRAVMRVYAERSGDAGARTPK
                     EIFEIAEGIRPGNREAAIAAFEELGEMAGDALASAITLIDGLIVIGGGLSGASKYILP
                     VLLKEMNAQTGMMDGARFGRLQKEVYDLDDEKSFAGFARGEAVEVLVPGTNRKVGYDP
                     CKRIGVTFSKQGANRSIAMGAYVFALNHLSK"
     gene            complement(14794..16539)
                     /locus_tag="ACZPB4_11255"
     CDS             complement(14794..16539)
                     /locus_tag="ACZPB4_11255"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009298 - GDP-mannose biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I mannose-6-phosphate isomerase"
                     /protein_id="HIR1098825.1"
                     /translation="MRKSNYDKMPATVVDGTLWKGWESIRKRLAEIHAETNGSQVWVV
                     ECYQGVHHEELMRELQALAPDRFINTRDLFKSAEDIEAMTYPYLTDDRLFGRRAHFSY
                     TDFLDEEKVNACRESLRDGKGWTIVYGHAAAEIVSAPDKLIYADMARWEIQMRSRRKE
                     VNGLGVENREEAPSYHYKRGYFIDWIVCDNLKKKVLPKVDYWLDTHIVRTPKMISGET
                     LKEGLEKTAHTPFRVVPFFDPAPWGGQWMKEVCDLNKKQDNFGWCFDCVPEENSLYLK
                     VAGELFEIPSNDLVFYKTRDLLGGPVEARFGQDFPIRFDFLDTMGGGNLSLQVHPVTQ
                     YIRDTFGIYYTQDESYYLLDAEEDATVYLGLKTGVNPDEMIAALNESQQTGKPFDTEK
                     YVNKWPAKRHDHYLIPAGTVHCSGAGAMVLEISATPSIFTFKLWDWGRLGLDGLPRPI
                     NIGHGSKVIQWERQTEFVRHNLINQVEMIAEGDGWREERTGLHENEFIETRRHWFTDI
                     VPHNTNGGVQVLNVIKGDELIVESPTGAFEPFIVHYAETFIIPACVGEYTIRPYGSSV
                     GKYCGTIKAYVRFRQ"
     gene            complement(16572..17873)
                     /locus_tag="ACZPB4_11260"
     CDS             complement(16572..17873)
                     /locus_tag="ACZPB4_11260"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0009311 - oligosaccharide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosidase family protein"
                     /protein_id="HIR1098826.1"
                     /translation="MNKILVVVSFVFVSFLSCTGLTDRQRLANQILSDTNLLKVDSMA
                     RATIRNGFNAGSGYSQIWARDMNTFIEIACEESDPHELREAILLFFALQQPNDEMIDG
                     YVLKEDFTWYDDTPYYSNAAPKHVAFKNTVETDQESSLIQIVGKYIRKTGDREILNEK
                     VVGKTVLERMNAMVDYLMRERYNEKYGLLYGAMTADWGDVQPNDDFGCDMNDLSDLAI
                     DVYDNAMFIIALDYLLEMAPDSPQASRWKSLREGIERNVRAHLWDVKRQKFIPHIYPE
                     KSPIPEGFDELAIHYHGGTAIAIEAGLLSKDEIRTVNAQMLENVRLSGMPSIGLTLYP
                     VYPDGFFHGGMSKAYLYQNGGDWTWFGGRMIQQLVVNGMVEEAYAEIHPMIERVIQND
                     GFYEWYGKGGVPSGSGNFKGSAGVLSKAIELLRDWAEKNKS"
     gene            17976..18866
                     /locus_tag="ACZPB4_11265"
     CDS             17976..18866
                     /locus_tag="ACZPB4_11265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HIR1098827.1"
                     /translation="MVKIKEGFKGERFVSLPEELLASYRREPLINNLYVRKIGFFPRV
                     KYHFLQKEHGCDYAMLIYCTEGKGWYRILGKQYTVEKYQYIIIPPGIPYSFGADEGDP
                     WTIYWLHFQGKLCDQFLPSHPVPVTISPNEYSRLQDRLRLFEEIYSSFSMGYIKEYMI
                     YSSMCLYNFLASFIYLEQFRHIMIPSQKEYPFTARVIHYMRENIQQNLTLKELASYFK
                     YSPSHFSALFFGETGVSPMNYFIRLKIQKACEYIELTNMKLNEIATHLGFEDAAYFSR
                     TFTKVMGCSPSVYRKKEMEI"
     gene            18954..20300
                     /locus_tag="ACZPB4_11270"
     CDS             18954..20300
                     /locus_tag="ACZPB4_11270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015501 - glutamate:sodium symporter
                     activity [Evidence IEA];
                     GO_process: GO:0015813 - L-glutamate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/glutamate symporter"
                     /protein_id="HIR1098828.1"
                     /translation="MIDLTQFTPWTLFTDLGFISILLLVGKFIRVKVKLIQQLFIPPS
                     LIAGLLGLAFGPNGLGWIPLSNDLGTYAAILIALVFGALPLSSPNVSMKEVAKRVGPM
                     WAYAQVGMLLQWALVGLFGLYVIKLIWPDLNDAFGIMLPTGFYGGHGTAAAIGSAFEG
                     LGWDEARSLGMTTATVGVICSIIGGLLMVKWAAKHKQTAFISDFDDLPDELRSGLLPE
                     DKRDSIGEATTSSISIDTLTFHVALVFVVAFLGYMVSQTVKVYYPVLELPVFSCAFII
                     GLVLKKFFDATTISRYICPQTTQRLSSSFTDMLVACGVASIKLGVIVKYALPLIVLII
                     AGVAIVWCITFFLGRRLAKTFWFERMIFAWGWWTGTMAMGIALLRIVDPKLSSKAMDD
                     YAMAYLPIAPIEILLITFVPILFVNGLGVWLLLACLVLSLLILLLAWKMGWWITRS"
     gene            complement(20287..22653)
                     /locus_tag="ACZPB4_11275"
     CDS             complement(20287..22653)
                     /locus_tag="ACZPB4_11275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1098829.1"
                     /translation="MKTIIRNFLSVLRRFKMATALNVAGLAVAFAAFIVILIQINFER
                     TFDRCHPTSGRIFRVDLTIPGTFGTILPRAFVEAVIQSSPHIEAGTLLTPSFGQNGVY
                     LSVDRNGQPFGFKEIVTTCHASLPKIFAFPIVEGDIDCLKDPEKVMVPRSLADKLFGE
                     DISAVGKTLRAEENIWTKSAKLFTIGAVYKDFPENTQLRNVVYTAIDPDYNINNFSSS
                     NWVCYLLLDNPAMADEVADNFNRHFDFKKIYHEGEQIRLVPLTDIYYMNETQDGGTFR
                     SGNKEVTALLFGIALLIVIVAAINFTNFSTSLTPLRIKSINTQKVLGSSDTLLRRSLL
                     IEAALISFIAWLVSLVIVWGLDWAEALPFIEADLSLVSNLPIVFLCGIVALVIGWLAG
                     IYPAYYITSFPPALVLKGSFGLSPSGRKLRTTLICVQFVVSIVLIIGACFVQIQNSYM
                     RNFSLGFDKDQVAIVELNETMYNKHHDTYVNRLKENPGIEDVAFAMEKVGSKDGYNTN
                     GGSYKGKDFQYFIIIASSNFLRVMGIPVIEGRDFSKADELSDHTSYIFNRTAMEGLDM
                     QVGDAFDSYSPGHLIGFSDDVKFTSLRGGEDNIAFLVGNFGYSLPISYIRLKAGSDIH
                     AVVGHIQETMRELDPSYPFNIEFYDEIFNHLYQKEENLRDLVTVFSLLAIIISLVGVF
                     GLVVFETQYRRKEIGIRKVHGATVGEILLMFNKAYLRIVGICFVIAAPIAWQGAKMWL
                     EGFAYKTPLHWWVFLIALLIVTVITLLTVSFQNWKAANENPVNSIKSE"
BASE COUNT         6408 a         5730 c         4511 g         6056 t
ORIGIN      
        1 cagaaattag gtaagcaggc ctttatcgag gaatgctgga cagagcgttt gcgtgagttc
       61 ccgttggaat tcaagatttg ggatgactgt ttgcgtacag gtaagttccc tgtaatctct
      121 tctacagaga agggtaaggt tacatacgtt gacttagttg gcgcaaagaa cgcttccggc
      181 gcgaccttca agtcttccga cttgttatgg ccgatctctt tgaacgagat gcaacgtaac
      241 ccgagtttga ctcaaaatga gggttatgcc gttcaataat aaatttcaat aactgatggc
      301 tagagaggga gggaatgagc gatcatcctt ccctctcttt ttggtagctt gattagtcag
      361 caagttgcat gaaacaatgt ataatataca gaattttggt ttggttgtct tattattcac
      421 tttcaactat gaaaacaaaa gagcaagaaa tgacatactg gattctgcta agttagaagg
      481 acggttggaa ggtgaagaaa aaagaatgat tttctgagca gtactactga cttgctcaaa
      541 ggatatatac ttattttgcc cacgcagtat atattacttt gccaagtcac taatacttca
      601 taaacatcct ttactttgac acaggctaga ggataagcaa ttgcttcctt ctgtaaacaa
      661 aaaacgccca aaattgctct ctgctataaa caatttgtta tatttgcata tatataagta
      721 cgattatgga gcgattgata gagatgtatc gaaagaagtt gcgatttacc tctaccgcct
      781 ttattagaag cacggtgtac gagattaatc gggatgcccg gttgatcggt ataagaggtg
      841 ctcggggagt gtaccgcaac agcatatcaa gcgaaatttt ccgcaagacg aacgaaccat
      901 atatgtcagc ttagatagta tctatttctc tgacaataca ttatatgact ttgcggatcg
      961 tttcgtgaaa cgaggaggaa cacgcttaca cttggatgag gtacataaat ccccccagta
     1021 aagccaagag ttgaagaata tatacgatga tatgccagaa ctgcaaatta tctttaccgg
     1081 ccccttttat cccgaatatc agtaagctct gcgaatggat tagtatcacg agaaacgttt
     1141 tattgactta tctaaacgta ttggcagaaa gtaagctgac ctacaactgt ttctactttt
     1201 ggtatctctc gcctgcaaaa gccggacaat atctacttga aaaatagaaa tctgatgtat
     1261 atcctctcgc ctttgaaagc gaatatcggc aacatgcggg agacgttctt tgcgaaccaa
     1321 ttgaaaaagt ctcaccaagt aacaacctta gatttacatc cgagtattac agataaaata
     1381 gaaaggataa atttgtaaag tatgagcgaa gccaacgatt ttttagtgga tggaatttat
     1441 acgttcgaga tcggtggcaa acgaaaaagg tactcaccaa tagaagggat accggacggt
     1501 tttatcgttg cggatgatat aaaaataaga tcccgttatg gatgatgggg ttcttgtatt
     1561 aaggaagaaa gggaagaata atcactcatc cttccctttc agccatcagt tattgaaata
     1621 aaaagtaatt acttcgctga atatccctca ttctgagtta aattcggatt acgttggatc
     1681 tcgtttacag ggatcggcca gtataagtct gttgccttga atgtagcacc gctaccattc
     1741 ttagcgccaa ttaaatcaac gaattgaacc tcacctttgt ttgtagcgga gatttgaggg
     1801 aatttacctg tacgaacaca gtcatcccaa atcttcattt ccaatgggaa ctcacgtaaa
     1861 cgctctttcc agcactcttc aataaaagct tgcttgccta atctttgaag ctcggaagcg
     1921 attgtagaaa catccttacc ttccatgtta gcacgtgcct taacttgtgc caaatagccg
     1981 gcagcctcag cgtttacccc actagactga gcgatagctt cagcggcaga taataatgtt
     2041 tcagcataac gatagaagtt ccagtctttc gtacccttac cagtctctaa gatagcagtc
     2101 tcatcatacc agtaccagtt acaaagcatc ttcatatcca gagttgttcc atcaacagga
     2161 tgcgtatatg tacgatggaa gaactgattc atctgggcac gcaagtcttt ctcaccatac
     2221 acattcaaat aacgctcgct aacaccatac acatttaccc acaaagagta tttgtttcca
     2281 gtagaagaat tagcgaagaa tgtcggagaa atcaaattga atgcgtgaac cgggatatta
     2341 ccgttaggag aaatagctgc gtcatattca cgggcataaa taacctctgg cagatcatct
     2401 gttgtacgta acttattgaa cgcactacct tccgcaaggt tatcgttagt agccaaagcg
     2461 aattttccgc tattgattac atctttcaat ggagtaaccg cattagcgta ctctcctagt
     2521 ctcatgtaaa catcggccag caacatatca gccgcatatt ttgtcacacg gtgactattt
     2581 cctgcaaaag tagcattagg taaattctct acagcaaact gtaaatcagg aatgataact
     2641 gtattgaaaa cttccgatgc agccgtacga gtcggatatt caaccaaagt agcatcttct
     2701 gtaggttctg taaccattgg aacatcacca aacattttta caagatagaa atagttcaat
     2761 gcacggaaga aacgagcctc tgctttatac tgagcttgat tatccatttc cacaccatca
     2821 acatacttga taactgcgtt cgctacattg atcgacttat aacaactttt ccaagtgtca
     2881 ttagtcaaat aattacaaca agattgcgta aagtcctgac gagtcaactg gcgagcatag
     2941 gaacagtcta cttcctgacc ttcatattca ttcacgaaat aaccagttac catgttcatt
     3001 acagacaagc tagaacctct ataagcacca gtcatattac ccatcttatc aggagcacca
     3061 tcacgatata gataattgac attgccaata atatcagcac ttgtcttata ataggtatcc
     3121 aaagtcaagg acgacttcgg atcctcatcc aaaaaactgt cacatgcggt aaatcctacc
     3181 aatcccgcac ataaaatagc tgttgttaat atttttttca ttgcaatttt ctgaataatt
     3241 taattaatta aaatattaca tttacaccca acgtaaacgt tctagctctc ggataagaga
     3301 agaaggccat attctgacca aattgttctg gagatactga accgttagat gtagagatct
     3361 gagatgtact ttcaggatcg tacccattaa agtctttcgc tgtaatcaag aacgcattgt
     3421 tcacattcaa atataggcgt aagctactaa acggagtctt tgccaattga tttgagtcaa
     3481 aagtataacc taactggatt aagttcgcac gtaaataaga accattagcc acccattgag
     3541 agtctgtcaa agtatcctgt cctgcgtgac caccgttgaa caaccagata gcttgctgca
     3601 tagaattagg attcgttcca ttatatgcgt catacaagat atttgtcaag ccgttagtct
     3661 gtccgaaacg gtcatatgta gagtgataga actgttgcaa ggtctgaaca ccagcgacaa
     3721 attgtaaatc caaagtgaaa tcccaattct tgtaacgtaa tgtattgatc atagatccag
     3781 tccaatcggg tacaccttta cctatgatct cacgctcaga agaacgtttc gcacgaccga
     3841 tctgtttctt ctggcagtta ccagcttcat aatcttctat tgtataaacg cctaaacgtt
     3901 tgtaaccata gaaactacct acgctttcgc ctacacgcaa gatagaagca ccgctcaccc
     3961 attcgttttt caagatatcc tcgtcattgt cacccaaaga taagatctta tttttattga
     4021 agttagcatt gatggatgtt gtccatgtga agtcttttgt atcaatattg cgagtagata
     4081 acatcagatc caaaccttgg ttacggatag aaccgatatt cttataaaca gtctcgaaac
     4141 ctgttgtatg aggaaccgga gcatccaata acagatcaga agtcttcttg ttgtaataag
     4201 aagcatctaa cgtaattcta ttattgaaca aacctaaatc gaaacctata tcgaactggg
     4261 cggttttctc ccatttcaga tcagagttag gcaatctatt taaataagaa taggaattac
     4321 gtgttccgtt caataataac gtttcgctct taactgttgc taaagatttg taaacaccaa
     4381 tctcagagtt accagtcaaa ccgtagctgg tatgcaactt caagttgctg atcgtatttt
     4441 gatcagacat aaagtcttct tgcgtgatgt tccaagccaa acccgctgat gggaagaacg
     4501 catatttatt attcttacca aacttagaag aaccgtcata acgaccagta attgtagcgg
     4561 agtaacgatc cttgaatgta taagcgaaac gtaagaaata ggagttcata gcccaacgtt
     4621 cccaataagt cttcggagca tcaggcttcg tacctgcgtc catattgaag tcctcaaaga
     4681 aatcggtagt gaagttttct gtatacattc tagaataatc atacttgcgc tcctgccaag
     4741 acaaaccggc catagcgttg atacggtgct cgccaatcgt cttattataa gtcaagtaag
     4801 tctcttcctg ccaataaaga gtatttgcat gatatctttc agcacgtcca tgttggtcat
     4861 atgccaaatt caccaagtca cttggcatat atttatgcaa agtcttaaag ttagcgtcaa
     4921 caccgaattg agtcttcaaa tccaaacctt cgatgatatg gaatgtcaag gctgcattac
     4981 cgaatacttt tgtattatag ttcatattct tataggtctt caagatatga acagggttag
     5041 acattgcctc aaagtccatt ggcatccctt ctggagtatt ggtggaggta tatttgccat
     5101 tatattgaac cggcatccaa ggaaccattt caatcatagt acgacgagca tcctgtccac
     5161 caccgtcttc tggagtagag ttaccccaag tatggttcac cgccaagttg atcgctgtag
     5221 ataaccatgt tgtaggattc gcatcataag cgatctttgc attcaaacgt tttgaatagg
     5281 tattcaacat gataccttgg ttatcagtat agttcaaaaa tgcacccata gatgatttct
     5341 cgccaccttg ctgaacattc aattgatggt tatgagagat cgctgtacga gttgcctcat
     5401 cttgccaatc tgtatcataa agaggattac cgttagaatc gaagaaacga cgatctgtaa
     5461 accaatccgc acgattagta gaccagttaa atggattgcc atccttatca gatccccatc
     5521 tattctcatt ctcaatacct tgcataaaag catcgcacca ctcctgcgca ttcatcgtat
     5581 ccatcttacg agcgcgatga gccaagctta cagaaccaga gtagctaacc ttcgttccac
     5641 cttctttgtt accacgtttc gtagtaacca tgataacacc attggcacca cgagcaccat
     5701 agatagcggt agcggaagca tctttcaata cctccataga ctcgatgtca ttcgggttca
     5761 tcaaatagaa gttctccatt actacgccgt ccacaacata caacggatca gaagaggcat
     5821 taattgtcgc ttgaccacgg ataacaacac ggctaccata agcacccggc tggctagagt
     5881 tagagaagat atttacaccg gcagccttac cacgcaagtt atccaatgca ctaaagtttt
     5941 gagcttttaa catctcttct cctttagctg tagaaataga acctgttaca tccgatttac
     6001 gcatcgtacc gtaacctact actactacct catccaaagt ctgtgtatct tctttcaatg
     6061 taacattgat tgcagattgg ttgcctacag ggatctcttg agataaataa ccaatatagg
     6121 aaatcaccaa aactccgtcg gcgggcacac cctcgatcgt ataatttcca tcgaaatcag
     6181 tgatcgtacc gtttgtagtg cctttcacca ccacgttagc gccaataaca ggctcacctg
     6241 taccgtcaac aaccacacct gttactttct tgccttgctg cactgccatt acttcatcaa
     6301 ccgtgcctgc gggagcggga gcggccatag cggcgtttac agagaaggca gaaagcagca
     6361 aacagaacgc tgaggcttta gctatcccct gaatggataa tagcttagat tcattctttg
     6421 tcattttgct ttgtttttta attaagttta gattgattac attgtctatg taatttttat
     6481 cgttatagat ggacatagtt cgtacggaac tagtgcgcca ttcatggtct atatcattaa
     6541 aaactgggca aatgtataac tttttttgta aactagactt aaatctatag tattttttta
     6601 ataaaaatga cacatttatc acaaatcacc ccttgaaacc aagaatatca gcccttaaat
     6661 gtactaaaaa tatattgttc cgtacggact tacaatagta tcatcgtctt tctatcacat
     6721 aaataattaa ctatcaaata ttaacagtaa aaacacttta aattggttac aataaacaaa
     6781 tgttaaattt attgagattc aaggctaggc gaaaatggca ctagtatggc ttctatgaaa
     6841 aaaacagata atatattcag agactggata atataaaaaa atttagcctt cctttataaa
     6901 taaaagaaga accacattat ctacaatctt tctaccaaga aagcgccata gacttattcc
     6961 cacaaggctt gaaatccaat aaggcattac ccgaaacaga gtctctcatg acactcttca
     7021 cccatcactc taacacaagc aagtcttctg cttagaataa taccgattta tttgggatta
     7081 aatcctatca aaacattcaa tatacaaaca taagacaaac tggataaggg cgggcaaacc
     7141 ccgcccctac catgctacca agataatttt ataaacttat tctcccacgg agcgaaactc
     7201 aacggattcc ccgaaactgg gtctcctacg acatcacaaa ccgtagtttt cacaaaatta
     7261 attttatctg aagttacgga gaaagtagct ggcttcccgc ctatctcacg caattgaagc
     7321 ataacagcat tctcgccttc cacaggcctc atgtttacca acaacaaatt ctccggtacg
     7381 atcttgaaaa tggaagccga ttggagaggc tccacctttt tatctccggc aggcaaaaca
     7441 cgggtcaaga acggaatccg gttttcccaa gcgaacttag tcgcatactc aatagagttg
     7501 tctttcgaag agttgatgaa gtaactccat tgcatctctc ccatttggtc cgcattgaaa
     7561 ttggttaccc agtagttgtt catcggccat gaatacatat tcgtggactg aggtacggct
     7621 ccggctttat accgccccgt attgatcgcc ccaaattgca ttaatggtat ttcttggcta
     7681 cccatcacga cctgtgactc tccattacga gccgtagcga agttttgcac cgtgtaccaa
     7741 tcgttagagg agcccgggat ttggtctaca cccgcctcaa tcgatccgcc gggtacatct
     7801 aaatggatct ttcctccttc aacctcaaac gggaaagcga tataaaccgc ttccggatct
     7861 gttaccgctt ttttgcgcag gcgataaact acctcgattt tctttgttac gttaaataca
     7921 cggaattcca ccatcaaatt attcggctca cgtcccgcta ccgtctctcc ccggaaacga
     7981 taggtatccc agacatcgcc tttctcatat ttctcgaaac gcatcttctc tgggcgacgg
     8041 cggaggaatt ggggagcacg atattgttcc atcggatgac ggctatcgat aatctcataa
     8101 ataaactcgc ccatctccca ttccgcatcc ggcgtaacca attgtttgtt caaatcctta
     8161 tcatataatt tacgaatcgt acctttacgg gtattgaagt cgatggcata ccaaggattc
     8221 tccacatgtg tctcttttaa ttccgtagcg ccctgtattt ccggacgtgg cgcatccttt
     8281 acctttatat aatactgcgc atatcccaaa gccgggacat ctttcacgta aaagttccaa
     8341 taagtaccat cggaacggct ttcgccggct tgtgcgggaa ttacgttgcc agccgtatcc
     8401 acgatctcga aagccttgtc tttcggaaga atctgatgat cgacataagc tttagcgata
     8461 ccgctataac tccagttgag cgtattgaat acagcgatag acggaacatc gcttttgggc
     8521 acgaacgatt gtaatatacc catagtggcc tctcccagca aaccggaatg gcgataggct
     8581 tcccacgcat acgattgttt caaggagcgt tgttcccaag tttccagtcc ataagcatta
     8641 cgtacgctct cactatgccc gaaagtatgc tcatcataga acaaaagagc tttgttgatg
     8701 tcctgaattc gatcattgat gtctgtcggc aattgagcgc ctagcatttt ggcgaatgac
     8761 aatccggctt ggttcgcgat aatatccgag tgagtcacac gagatatggc ggcctcgcgg
     8821 gcaccggaac caaaaccatc cgtccaccaa tccggccaag ctccacgaat ggtctcgata
     8881 cgatccgcat attggctctc taccgtctta aagaactcgc tggctaccgc cgtgcgtaat
     8941 ttcggccatt catacttctc attccatttt tgtagcatct cacaactttt cgtggatgga
     9001 ggcgcattat ccgtaaaata acccgaatgc tgggcggcca atatatcata cggatagttt
     9061 ttcgcttcca tttgatccag atacgctaag acccgttcct cgaactgctc aaaatcatcg
     9121 gtatggatac caaagaaatt tccttggtta taatgctcgg cacgataggt caagaccttc
     9181 ttcccggatg gagattccca ccagaatacg gtaggtttat caaaacagat caacgcccgg
     9241 tggccatggg ttcccatatt cacatatttc acgccggcat ccgcaaaata ctcgctgaag
     9301 caccaaccga ttccattcac gtcgtcttgc atagctacct cggcacgcat cccattctca
     9361 cggaattgct tgatcggata aagggaggcg gcgagcgttt gctcatcggg taattcgtca
     9421 aagttcaagt acatcgtagc taattcgata cgaccctctt ttacccgctg cttcaggcga
     9481 gcgatctgtt ccgccggacg gcatttcaaa tattcgctaa ccgcccaagc gatctcgcaa
     9541 gtccaacgga atttagcgaa atccggataa ttatccgtag cgtcgcaata atccaatgca
     9601 taatcaatat atcgtagatg ttccgctagg atttccattt gggaacgggt ataaccgata
     9661 tccgtatgcg tgtgttgcac catattcatt tgccaatggc gaaccggttt taccgtcacc
     9721 atagtctcct ctttctcttt cccacttgtc agcgtcaacg gtaattggcg agtcgtgcta
     9781 acctcgggta tctcgattcg gaacacatta tccccggaca ccagtttctc tttacggctt
     9841 tgctcgccta aacggatcgt tactgtagaa ggctctcctt catgtttcac ggagatctcg
     9901 accttttggg tcagtccgtt tttcgattta taaaccgccg gcaatacacg gctcttgaca
     9961 tccgataatc ccggagacgc atggaccgac aatgtcccaa tcaacaaagc caatcctgct
    10021 gataaataag ttcttttttt cattttatcg tgtttttatg gatataagtc ctatatacaa
    10081 catacatatt aataatagca tcaagccggc tacctgcccg aacatatcgg ctaagcctcc
    10141 catacaaggc gtaatcaagg cgcctcccga tacccccata atcatcaagg ccgatacctc
    10201 gttggattgc tccggacgat gttccaacgc gaaagagaac aggatcgaaa acacattcga
    10261 gcaagccaag ccaaccagta cgatcataac gcccatgctc cacaagctat ccgagataag
    10321 caatcccacg aaagcaagga taacgatcag catgcttccc cttaagaaag gtcgtgacga
    10381 gatcctcgcc aacaatatag cccccaggaa agagcctccc gtacgagcgg cgaaataaag
    10441 gctactccct aatccggcct cttgcaacgg catggataac ttttccatca atagcttggg
    10501 gatcgtcgta ttcagaccga catcgatccc gacaatacac agaatcccca agaaaagcat
    10561 ccgtatccta gcatctttac ataaagctaa tgtagaggcg aacgaggctt cttgctcctc
    10621 tccttcctct ttacccggaa tagccgttat caaccaaatg atagacaaca aggtagtcac
    10681 cgaatagaca atgaatatca acttccaatc cccccaaaaa gaggaagcga cccccgcaat
    10741 aatcggacct aagaaggaag ataccgcctt aataaactgc cctaacgtaa gcacgctcgt
    10801 taccttatcc ggatttacca cccgggctac catcgggttc aaagatactt gcaaaatcgt
    10861 atttccaatt cccagcaaag cgaacgcaaa caagatacaa gcaaagtcat agaagaaaag
    10921 aggtatcagc atcgccaagg tcgtgatggc caaggcagcg actaccgtat tcctacgccc
    10981 gtgccgtccc atccagatac cggtggggac agagaacagg gcgaaccaaa gaaagaccat
    11041 catgggtaat aggttcgcca aggtgtcgga caaaccaaaa tccatcttca cataattcgt
    11101 ggcaattccc acgacatcca cgaatcccat cacaaaaaag ccgaaaagga tcgggaatat
    11161 agcggagttc gtacttttag ttctcatatc catcttttgg ttggctaccc atttctaaaa
    11221 ccaaatgtcc accttgaata atctccgaga aaggaatacg agtatccgtc aatggtttcc
    11281 cgtttaagtt catcgattgc acgtaatcat tttgcttact attattacgg gcctcaatca
    11341 cgaattcctt ccctttataa tagcggtcat tcagccggat cgtaatctta tcgaataaag
    11401 gactgcccaa agcgaaagaa ggcgcttgat ccgtcaagcc tttcatatcg aataagccta
    11461 aggaagagat cacgtaccaa gccccaagct ggccttgatc ctcatcttgt ccgtagccat
    11521 aaccgtggat gccatccgta ccatagaact cattcaagat cgcccgtacc catttttgcg
    11581 taagcgaggg acgaccggcc tcgttgaaca tccaagggat gtgcaagcac ggttggtttc
    11641 cttggttata caaggtttgc aaaccggcga aagcccctac ttccgtgcct ccgctaaaga
    11701 ttaatttacg agacaccgtg aagatgctat ccaaccgatg gttaaacacg tctgcgccta
    11761 ctttcgcgac caagcctttc gcgtcgtgcg gtacatagaa tgtatattgc caagcgttac
    11821 cttcttggaa tccgcgccat acttgcatcg gattgaagtc ctcgataaac gtaccatcct
    11881 tctttttagg acggacaaaa ttacaggaag ggtcatagat acgctcccag cctttcgata
    11941 agtccttcaa acggttataa tcgtccgtct tacccagttg cttcgcccat tgggccacgg
    12001 cccatgcgct ataagcatat tccaaggtat gggaagcgga gaacatgaaa gcctcgtccg
    12061 gcccgtcccc cttatccaaa tgaggcacat aaccatattc cacgaaataa cgggtatcga
    12121 tctttcctgc gcccaatgga cgattctccc catccaactc attcttcaag caagcctcat
    12181 aggccgtatt cacatcgaaa tcccgaatgc cacattgata agcgccagcg ataatcgtac
    12241 ttaataaatt cgtaccaacc ccggagacat aacggctatt agcgattcca tccgccagcc
    12301 agccggcgtc cttgtacacc aacaaatggc tacttatata atccgaataa tattccggat
    12361 aggccaaagc ccaaacctgc gtcagattcc attgcgctcc ccaagcggca tcggtattat
    12421 ataagttatg tatcggtttc ccgtctttca aagggatttg tcctaccgag ccatcatttc
    12481 tcggataagc gccattcacg tcgctagcca atccgcggcc caataaagca tgatacaaac
    12541 cggtatagaa tttcacctta tcctcttgcg ccggagtctc tacccggata cgtcccaaat
    12601 attcttccca tgtttggcga gagatttccc ttgcttcgtc aaacgtaagg gtagcggcct
    12661 ccgtctccct atttaaccgg gcattctcca cggatgtata ggaaagacct actttagcgg
    12721 ttaccgactc ttgatcttgg gtacggaatg tcaaataaag tccggctccc acacccgtcg
    12781 cttttcgttc atccggacgg atatccgccc cgttgaaagc gccatatcca acgggagcct
    12841 tatccagcac cgccgagaaa tacaaaggaa ccgatgcccc gggctggtat ttcctcacat
    12901 attcaggctc ggtaatcacc cagccctcga tacgcccgtc ttccgtaaaa gtaatttccg
    12961 cgtcccgcac ggctccgctt tctccttggc ggtttcctat atcgaacaag atacggctat
    13021 cctccccggc cggaaacgta taacgctgga tagcgacacg aggggtagcg gtaagctccg
    13081 cccggatcga gtaatctttt aggagaacgg aataataacc ggcggtagcg atctcgtccg
    13141 cacgatcaaa acgggaacgg tatcctatac ctgtcgagtc gtctaccgcc ccgggaattg
    13201 ttttcaatga acccgtcgta ggcatcaaga cgattccacc gatctgaaac tcatgcaagc
    13261 aggggaaacc ctcgatcgat tgatcccgat aatcgtaacc ggtagcctcc caaccggatt
    13321 tattcccgat atgcccgttc gtagaagggg ccggcttggc cataccgaaa ggcatcgctc
    13381 ccggggtaaa atgaaaccaa cggcaatgcg ccgtgccgat ccgaggctct acatattggc
    13441 taagctcctc ttgctggacc ttcttgcctt gtgtcacgca ggatgtgaaa accccgcaca
    13501 ggaacaagag gaaacagacc ggcttcatac tatactttct cataatttat ttagatagat
    13561 ggtttaacgc aaaaacataa gcacccatag cgatcgagcg gttggctcct tgcttgctga
    13621 aggtcacccc tatccgttta caaggatcgt atcctacctt gcgattcgta cccgggacta
    13681 gcacctcgac agcctctccc cgggcaaaac cggcgaagct cttctcgtcg tccaagtcat
    13741 acacctcctt ttgcaagcgc ccgaaacgag caccgtccat cattcccgtc tgcgcgttca
    13801 tctctttcaa caagaccggc aggatgtact tggaagcacc ggacaaacca ccgcctatca
    13861 cgataagccc atcgatcaag gtaatagcgg aagccaacgc gtccccagcc atctcaccca
    13921 actcctcaaa cgcggcgata gccgcttccc ggttacccgg acgaataccc tcggcgatct
    13981 cgaagatctc tttcggggta cgcgcccccg catcaccgct ccgctccgca tagacacgca
    14041 tgaccgcccg tatgctgacg ctctcctcca cgatatactc cgggtacttc ttgttccgca
    14101 ggcaccatac atatcctccc gccgcgttat caccccgcaa aagctctcca tcgatgacaa
    14161 ccccggcacc aaagcctgtc cctagcgtga cacctagcaa attcttatat cgtttcgtac
    14221 ttcccgcctc ccgcaaacgg cggttgatct ccgggagcac tcccgtcaac gcctctccgt
    14281 acgcaaacaa gcttccgtcg ttattgataa ataccggtat cccgaatata tcttccagaa
    14341 acgggcctaa cgctacgcca ccccggaaag aggggaagtt gggtaaatcg cctatgatac
    14401 cggcttgata atccgccgga ccaggaaaag cgaaactgat agcgaccgga gcttccggca
    14461 agcctgcttg aattgcctta aaaccctcta ccaaattacc taaacactta tccaagcaat
    14521 ccgcgcatgc cggaagaact accggatcgg ctatctcttt tccaccttgg atggcagaga
    14581 agacaaaatt cgttcctccc gcatccaatg tcattactat tctattgtca tttgtgtaca
    14641 tcatatattc cttttcttta cttaaagagg tcccgccagt gccacagcag tggcactact
    14701 ttgccattag aggtgacaca accttgcctt cgaagtggca caatcgtgcc atcagtagtg
    14761 gcaaagcagt gcaatgccta tggcaaacgg tgattattgc ctaaaacgta cgtaagcctt
    14821 tatagtacca caatatttac ctacagacga tccatacgga cggatcgtat attcacccac
    14881 gcaagccggg atgataaaag tctccgcgta atgaacgatg aaaggttcga atgcgcctgt
    14941 cgggctctcc acgatcaact catctccctt gattacattc agtacttgca cccctccatt
    15001 cgtattgtga ggcacgatat ccgtgaacca atgacggcgg gtctcgatga actcgttctc
    15061 atgcaagccg gtccgctcct cccgccaacc gtctccctcg gcgatcatct ccacttggtt
    15121 gatcaagtta tgacggacaa actccgtttg ccgctcccat tggatcactt tcgagccgtg
    15181 gccgatatta ataggtcgag gcagtccgtc caatcccaag cggccccagt cccaaagctt
    15241 aaacgtaaag atacttggcg tagcgctaat ctcaagcacc atggcaccgg ctcccgaaca
    15301 atggaccgtt ccggcgggga tcagataatg atcatggcgt ttggcaggcc atttattgac
    15361 atatttctcc gtatcgaaag gctttccggt ctgttgggac tcgtttaggg cagcgatcat
    15421 ctcgtccggg ttgacaccgg ttttcaatcc cagataaacg gtagcgtcct cctcggcatc
    15481 cagcaggtag tagctctcgt cctgcgtata ataaatcccg aacgtatccc ggatatattg
    15541 ggtgaccgga tgcacttgca aacttaggtt tcctcctccc atcgtatcca agaagtcgaa
    15601 acggatcggg aaatcttgtc cgaaacgagc ctcgaccggc ccgcccagca agtctctcgt
    15661 cttatagaat accaagtcat tggaagggat ctcaaacagc tctccggcaa ctttcaggta
    15721 taaactattt tcctcgggca cgcaatcaaa acaccaaccg aagttatctt gctttttatt
    15781 cagatcacag acctctttca tccattggcc gccccaagga gccggatcaa agaaaggtac
    15841 tacccggaac ggagtatgcg ccgttttctc taacccttct ttcaatgtct ccccggaaat
    15901 catcttaggt gttcggacga tatgggtatc caaccaataa tcgaccttag gaaggacttt
    15961 cttcttcaga ttatcgcaaa caatccaatc aataaaatat cctcgcttat aatggtacga
    16021 cggggcttcc tcccggtttt ccacacctag cccgttcacc tcttttctac gggaacgcat
    16081 ctggatctcc caacgagcca tatccgcata gatcaatttg tccggagcgg aaacgatctc
    16141 ggcggcggcg tggccataaa cgattgtcca gccttttcca tcacgcaagg actcccggca
    16201 ggcgttcacc ttctcctcat ccaagaaatc cgtataagag aaatgagccc ggcggccaaa
    16261 caaccggtca tccgtcagat aaggataggt catcgcctct atatcttctg ccgatttaaa
    16321 taaatctcgc gtattgataa aacgatcggg cgcgagcgct tgcagttcac gcatcaactc
    16381 ctcgtgatga accccttggt agcattccac cacccaaact tgtgatccat tcgtttccgc
    16441 atgtatctcc gccaatcgct tccgtatcga ttcccagcct ttccacaagg taccgtctac
    16501 aacggtggcc ggcattttat cataattact ttttctcatc tcttttgaca tttaatattg
    16561 cacgcttgta tttaactctt atttttctct gcccaatccc ttaataattc aatcgcctta
    16621 gataacactc cggccgatcc cttgaaatta ccagagccgc tggggacacc gcctttgcca
    16681 taccattcgt agaatccgtc attttggatc acacgctcga tcatcggatg gatctccgca
    16741 taagcctcct caaccattcc attaacgaca agctgctgga tcatccgacc gccaaaccat
    16801 gtccaatccc cgccattctg atacagataa gccttagaca ttcctccatg gaaaaaacca
    16861 tccggataca cgggatataa ggtcagacca atgcttggca tacccgacag gcgaacattc
    16921 tcaagcatct gggcatttac ggtacgtatc tcgtctttcg ataataagcc ggcctctata
    16981 gcgatagccg tcccaccatg ataatgaatg gcaagttcat caaaaccttc cggaatcgga
    17041 gatttctccg gataaatatg aggaatgaac ttctggcgct ttacatccca tagatgagcc
    17101 cgcacatttc tctcgattcc ctcacgcaga cttttccaac gggaggcttg cggagaatca
    17161 ggagccattt ccaacaaata atccaaggcg attatgaaca tagcgttatc atatacatcg
    17221 atagccagat ccgacaaatc attcatatca catccgaaat cgtcattcgg ctgtacatcg
    17281 ccccaatcag cggtcattgc tccataaagc aatccatatt tctcattata tcgttcccgc
    17341 atcagataat ctaccatcgc gttcattcgc tcgagaacgg tcttcccgac aactttctca
    17401 ttcaatatct cccgatcacc cgtcttacga atgtatttac ctacgatctg aatcaaggaa
    17461 gattcttggt ccgtctctac cgtattctta aaagcgacat gtttcggagc ggcattcgaa
    17521 taataaggcg tatcatcata ccatgtaaaa tcttctttca gcacataacc atcgatcatc
    17581 tcatcattcg gctgttgaag agcgaaaaac aataaaatag cttcccgcag ttcgtgtgga
    17641 tcactctcct cgcaagcgat ctctataaac gtattcatat cacgagccca tatctgggaa
    17701 taaccgctac ctgcgttaaa accattgcgg atggtagcac gagccatact atcgaccttc
    17761 aacaaattcg tatcagacaa tatctgattg gccaatcgct gtctatcggt taatcccgta
    17821 caagacaaaa aagatacaaa tacaaaagaa actacaacta gaattttatt catggcatta
    17881 tgttatgatt tatgtcggca aaattatttc aataatccag aaagaaatgc tacatttgtt
    17941 ccgatttact tgtacaatct tatgatttat agatcatggt caagataaaa gaaggattta
    18001 agggagaacg gttcgtttct ttacccgagg aactattggc aagctaccgg agggaaccgc
    18061 tcatcaataa tttatatgta cgcaagatag gtttcttccc acgtgttaaa tatcattttc
    18121 tccaaaaaga acatggctgt gactacgcca tgcttattta ttgtacggag ggaaaaggat
    18181 ggtatcgtat cctcggtaaa caatataccg tggagaaata ccaatatatc atcatccctc
    18241 ccggtatccc ctactcattc ggggcagacg agggagatcc atggactatt tactggttac
    18301 acttccaagg gaagctttgc gatcaattcc tgccgtcgca tccggttccg gtcactattt
    18361 cgccgaatga atattcccgt ttacaagatc ggttacggct gtttgaggag atatatagca
    18421 gtttctccat gggatatatt aaagaatata tgatttattc ctccatgtgc ctttacaatt
    18481 ttctggcctc tttcatctat ctggagcaat tccgccatat catgattccc tcgcaaaaag
    18541 aatatccgtt cacggcacgg gttattcatt atatgcgtga gaacatccag cagaatctta
    18601 ccttgaagga attagcgtct tatttcaaat attccccttc tcacttctct gctctcttct
    18661 ttggcgagac cggggtctcg cccatgaatt acttcatacg cttgaaaata cagaaggctt
    18721 gtgaatatat cgagctaacg aatatgaagt tgaatgagat cgccacgcat ctgggattcg
    18781 aggatgccgc ctacttctcg cgtacgttta cgaaagttat gggttgctct ccttccgttt
    18841 atcgtaaaaa ggagatggag atatagaatt cgtttggatt tctagtattt ctcataagaa
    18901 taaaatatat ttgtacaata gatatttaaa cgaacataaa gtaagtagtt actatgatag
    18961 acctaacaca gttcacccct tggactctct ttacggatct tggattcatt tcgatacttc
    19021 tattggttgg caaattcata cgagtcaagg taaaactgat acaacaatta ttcatacccc
    19081 ccagcttgat cgcgggcttg ctaggactgg cgttcggacc taatggactg gggtggattc
    19141 cgctttccaa tgacttaggt acttatgcgg ctatccttat cgccttggtg ttcggcgcgt
    19201 tgcctttatc ttccccgaac gtctccatga aagaagtagc gaaacgagtc ggaccgatgt
    19261 gggcgtacgc tcaggtgggt atgttattgc aatgggcatt ggtaggcctt ttcggattgt
    19321 acgtgatcaa actgatctgg ccggacctga atgacgcttt cggcattatg ttgccgacag
    19381 gcttttatgg cggacacggc acggccgctg ctatcgggtc tgcgttcgag ggattgggct
    19441 gggacgaggc tcgcagttta ggcatgacaa ccgctaccgt gggggttatt tgctcgatca
    19501 tcggaggttt actgatggtc aaatgggcgg ccaagcataa acaaaccgct tttatctcgg
    19561 atttcgacga tctaccggac gagctgagaa gtgggttgct gccagaggat aagcgggatt
    19621 ccatcggaga agctacgact tcctccatat ccatcgatac gctgactttc catgtggctt
    19681 tggtatttgt cgtggctttt ttgggatata tggttagcca aaccgtaaag gtgtattatc
    19741 cggtattgga gttacctgtt ttcagttgtg cctttatcat tggattagta ttaaagaaat
    19801 tcttcgacgc aacaaccata tccagatata tctgcccgca gacgacccag aggctgagca
    19861 gttccttcac ggatatgctg gtagcttgcg gtgtagcgtc tatcaagcta ggggtgatcg
    19921 taaaatatgc cttgccgctt atcgtactca tcatagcggg cgtggcgatc gtctggtgta
    19981 taacattctt cttaggaaga agattagcca agaccttttg gttcgagcgc atgattttcg
    20041 cttggggatg gtggaccggc acgatggcca tgggcatcgc cttgctgcgg atcgtcgatc
    20101 cgaaactttc cagcaaagcg atggatgatt atgcgatggc ttacctgcct atcgctccca
    20161 tagagatctt attgatcacc ttcgtcccca tccttttcgt aaacggattg ggagtttggt
    20221 tgctattagc ctgcttggtc ctttccctac tgatcttgct actggcgtgg aagatgggat
    20281 ggtggattac tcgctcttga tactatttac cgggttctcg ttcgccgctt tccagttctg
    20341 gaaactcacg gtcaataacg tgattacggt tacgatcaat aaggcgatta agaataccca
    20401 ccaatgaagc ggagtcttat aagcgaaacc ctcgagccac atcttcgcgc cctgccaagc
    20461 gatcggcgcc gctatcacga agcaaatacc tacaatcctc agataggcct tattaaacat
    20521 cagcaggatc tcccctaccg tagctccatg taccttgcgg atacctattt ccttacggcg
    20581 gtattgagtc tcgaacacca ctaagccaaa tactccgacc aaagagataa taatcgccag
    20641 taaactaaaa accgtaacca gatcgcgtag attctcctct ttctggtaaa gatgattaaa
    20701 gatctcatca tagaattcta tattaaacgg ataggaagga tctaattctc tcatcgtctc
    20761 ctgaatgtga cctactacgg catgaatgtc cgatccggct ttcaagcgga tataagagat
    20821 tggcaaagaa taaccaaagt ttccgaccaa gaaagcgata ttatcctctc caccacgaag
    20881 cgaggtgaat ttcacatcgt cggagaaacc gataagatga ccgggagaat agctatcgaa
    20941 cgcgtcaccc acttgcatat ccaacccctc catcgccgta cgattgaata tataagacgt
    21001 atgatccgaa agttcgtccg cctttgagaa atctctccct tctataaccg gaatccccat
    21061 cacccgcaag aaattggaag atgctataat tatgaaatac tgaaagtcct tacccttata
    21121 actaccgcca ttcgtgttat acccgtcctt agagcccact ttctccatag cgaaagccac
    21181 atcctcgatc cccgggttct ctttcaagcg attcacatat gtatcgtgat gcttattgta
    21241 cattgtctca ttcagctcca cgatagctac ctgatcctta tcgaatccta aagagaaatt
    21301 cctcatataa ctattctgga tttgcacaaa gcaagccccg ataatcaaca cgatcgaaac
    21361 aacgaactgg acacaaatca atgtcgtacg taacttacgc ccggaaggag ataacccgaa
    21421 gctgcccttc agcaccaagg ccggaggaaa agaagttata taataagcag gataaatgcc
    21481 cgccagccaa ccgataacca acgctacgat gccacacaag aaaacgatcg gaagatttga
    21541 gaccaaactc aaatcggcct cgataaaagg tagcgcttcc gcccaatcca atccccaaac
    21601 gataacgaga cttaccagcc atgctataaa actaataagg gctgcctcta tcaataaaga
    21661 tctgcgcaac aaagtatccg agctacccaa taccttctgc gtattgatgc ttttgattcg
    21721 caacggagtc agagaagtgc taaagttcgt gaagttaata gccgcgacaa tgacgatcag
    21781 aagggctata ccgaacaata aggccgtgac ttccttgttt ccgctccgga atgtaccacc
    21841 gtcttgcgtc tcattcatat aataaatatc agtcagcggg acgagccgga tctgttctcc
    21901 ctcatggtaa atcttcttga aatcaaaatg acggttgaaa ttatcggcaa cctcatctgc
    21961 catggcagga ttatcaagca ataaataaca aacccagtta cttgagctaa aattattgat
    22021 attataatcc ggatcgatcg ccgtatagac cacgttccga agctgcgtgt tctccgggaa
    22081 atccttataa accgcgccaa tcgtaaagag tttagccgat ttagtccaga tattttcttc
    22141 cgctcgcaac gtcttaccaa ccgcagagat atcttcccca aacaacttgt cagccaagct
    22201 tcggggtacc attactttct cgggatcttt caagcaatcg atatcgcctt ccacgatcgg
    22261 gaacgcgaat atcttcggta aactagcgtg gcaggttgtc acgatttcct taaacccaaa
    22321 cggttgcccg tttctatcca ccgagagata aacaccattc tggccaaaag aaggagtcaa
    22381 caatgtaccc gcctctatat gcggggaaga ttggatgaca gcctccacaa aggcacgggg
    22441 taatattgtc ccgaaagtac ccggaatggt caagtccacc ctaaaaatcc gcccggacgt
    22501 aggatggcaa cggtcaaaag tccgctcaaa attaatctgt atcaaaatca cgataaaagc
    22561 ggcgaaagca accgcaagac cggctacgtt caatgcggtc gccattttaa accgcctcaa
    22621 cacacttaga aagtttcgaa taatcgtttt cattttatta tagtttcatt tattattccg
    22681 ttttaatact atccaccgga ttcgc
//
LOCUS       DBMDTB010000067        22296 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_791_length_22296_cov_13.813562, whole genome shotgun sequence.
ACCESSION   DBMDTB010000067 DBMDTB010000000
VERSION     DBMDTB010000067.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 22296)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 22296)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22296
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_791_length_22296_cov_13.813562"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            221..1678
                     /gene="rpoN"
                     /locus_tag="ACZPB4_11280"
     CDS             221..1678
                     /gene="rpoN"
                     /locus_tag="ACZPB4_11280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HIR1098830.1"
                     /translation="MLKQQLQQKLQQKLSPQQIQLIRLLELPAIELEERVKHELEDNP
                     ALEEGKEPVDDFERTESEEGGEEIPSVDTETDLSLGDYLTEDDIPDYKLREMTERAER
                     KEDVPFSVSQSLNEFLLQQLGLRDLPDKQMKIAEYIIGNIDDDGYLRRDLSAIADDLI
                     FQAGQEVDEKEIESILNIIQDFEPAGVGARDLKECLLIQLDKKENTPVTNLAIRVLTE
                     YFEEFTRKHYDKILRGLDIDEETLKKVIHEITMLNPKPGSSWGGSMEVAMSQIIPDFV
                     VEAHNGELILSMNNRGVPDMRINREYAEMFQDYTANKANQTAERRDAVQFVKQKLDSA
                     QWFIDAIKQRNETLQRTMEAIIYLQRDFFLTGDEATLHPMILKDVAERAGYDISTISR
                     VSNSKYVQTNFGIYPLKYFFSESMQTDTGEEISTREVKKIMKEHVDAEDKRKPLTDEE
                     LATILKEKGYVIARRTVAKYREQLGIPVARLRKEI"
     gene            1685..2305
                     /locus_tag="ACZPB4_11285"
     CDS             1685..2305
                     /locus_tag="ACZPB4_11285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HIR1098831.1"
                     /translation="MKLFSNIISFVFHPLLMVTYGIVLALMFTFLAIYPLPVKLLIAG
                     GTFISTAIVPGLFIFLLVKNGAAGDIELSDRKERVVPYLIFITSILVCIFFLYKMLMP
                     FWLLAMLIGACVALVIALCVNFAWKISAHAIGIGGLLGAIMGVARIHMINPYWAFIVV
                     LIVAGLLGTSRIFLKRHTPMQVYAGFCLGFICTFVASLMSYIYLFI"
     gene            2322..2702
                     /gene="gcvH"
                     /locus_tag="ACZPB4_11290"
     CDS             2322..2702
                     /gene="gcvH"
                     /locus_tag="ACZPB4_11290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004584176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005960 - glycine cleavage complex
                     [Evidence IEA];
                     GO_process: GO:0019464 - glycine decarboxylation via
                     glycine cleavage system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein GcvH"
                     /protein_id="HIR1098832.1"
                     /translation="MNFPADLKYTKDHEWIRVEGDVAYVGITDYAQGELGEIVYVDIT
                     TEGETVAKEEVFGTIEAVKTVSDLFMPVSGEVLEVNAELEDAPELVNEDAYGKGWLIK
                     ISLTDASELEELLSAEDYQKLIAK"
     gene            2705..3211
                     /gene="purE"
                     /locus_tag="ACZPB4_11295"
     CDS             2705..3211
                     /gene="purE"
                     /locus_tag="ACZPB4_11295"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009860133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HIR1098833.1"
                     /translation="MTPVVSIIMGSTSDLPVMEKAAKFLDEMEIPFEMHALSAHRTPA
                     EVEAFAKGAKGRGIKVIIAAAGMAAHLCGVIASMTTVPVIGVPINSTLDGMDALLAIV
                     QMPPGIPVATVGINGALNAGILAVQMLAVGDEQLQEKLSAYKEDLKKKIVKANEELAK
                     VSFKYKTN"
     gene            3318..5153
                     /locus_tag="ACZPB4_11300"
     CDS             3318..5153
                     /locus_tag="ACZPB4_11300"
                     /EC_number="1.17.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-methylbut-2-en-1-yl diphosphate
                     synthase"
                     /protein_id="HIR1098834.1"
                     /translation="MAYFNYNRRKSSVAQIGDTPMGGENPIRIQSMANVSTMDTEAAV
                     AQAIRMIEAGAEYVRFTAQGEREARNLGEIRKQLNEQGYTTPLVADIHFNPRAADAAA
                     GEVEKVRINPGNYVDKVKTFSHLEYTDEEYAAEIERIRERFVPFLNICKAHGTAIRIG
                     VNHGSLSDRIMSRYGDTPEGMVASCMEFLRICREENFPDVVISIKASNTVVMVRTVRL
                     LVRTMEAENMHYPLHLGVTEAGDGEDGRIKSAVGIGTLLCDGIGDTIRVSLSEDPEAE
                     MPVARKLVDYIRERENHRPIEASMAPGFDTVATSRRISRVVEGIGGTFSPVVISDRSS
                     GDFEFDYLSLPDYIYIGKEDPDNLPDNFRLLVDAHFWKERPNAFPCFIASEAEELKDY
                     DCPLKFIRLTYMDLTDRMLEILKADKTVVVLLSTHHRNGVGSQRAAMHKLLMAGCDVP
                     VVLHRDFRETDVELLQLKSAADFGTLLLDGFGDGLMLHNEGCEAVVSDRCMFGILQAT
                     RTRISKTEYISCPSCGRTLYDLQTTIARIKEATSHLKGLKIGIMGCIVNGPGEMADAD
                     YGYVGAGRGQISLYKGKECVLKNIPEEDAVERLVQLIKENGDWVN"
     gene            5187..5621
                     /gene="dut"
                     /locus_tag="ACZPB4_11305"
     CDS             5187..5621
                     /gene="dut"
                     /locus_tag="ACZPB4_11305"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004170 - dUTP diphosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006226 - dUMP biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0046081 - dUTP catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HIR1098835.1"
                     /translation="MKVRIINKSHHPLPGYATPLSAGMDIRANLSESVVLKPLERKLI
                     PTGLYISLPEGYEAQMRPRSGLALKHGITLLNTPGTIDADYRGEIGIILVNLSSEPFT
                     VNDGERICQMVIAAHSHVDWEPVETLDDTERGAGGFGHTGKE"
     gene            5650..7368
                     /locus_tag="ACZPB4_11310"
     CDS             5650..7368
                     /locus_tag="ACZPB4_11310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HIR1098836.1"
                     /translation="MFKQLIYLISFLSLVAVLPAGATETEKDQRKFDYFFYEGLNLKN
                     AGKFDAAYDAFNHCLEIDSTAAPVLYELSSFYVQLNRPEKAVEMLKRAVANSKDNFTY
                     KMALASITRNLGMYGEAAEEYEELVRDYPEKEELNYYLADALTQAGEIGKAIEAYDAL
                     ESVMGMNEAISMQKYKLYVQLEKPEEAFKEIEKLAAKYPMEARYQIVLGDLHLENGEM
                     DKALACYQKANEIDPTDPYYIVSMANYYEAKGDKEAAEQQIRSALVNEKLDVETKVNI
                     LSRYILKLQQTKQGTENANHLFQTLLEQHPEDIDLKLMYGGLLMAQGKTEEAKFQFQL
                     VTEMEPGNAGAWQQLLNLALKGEDIPEVIRICTACMELFPESPEYYFYLGIAYYQQQK
                     YQEALNTYYAGLNIIPKENLPLKSDFYGQIGDIYYQMGQLDQAYKAYDEALKYNDKNV
                     VVLNNYSYFLSLEKKDLKKAERMSAQCIKLEPDNATYLDTYAWIFFVQGNYTLAKIYI
                     ESALEKDKTKSAELVDHYGDILFMNGDKEKAVEQWKKAKEMGKDSEILNRKIAEQQYI
                     EDENAK"
     gene            7365..8210
                     /gene="lolB1"
                     /locus_tag="ACZPB4_11315"
     CDS             7365..8210
                     /gene="lolB1"
                     /locus_tag="ACZPB4_11315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein insertase outer membrane protein
                     LolB1"
                     /protein_id="HIR1098837.1"
                     /translation="MKRDYFLTFLLCGGLLLSMLTGCKSSKKVGTVESASVKAHNEFF
                     QSVEDQSFQFRTLTARLNVDLDIPGKQMSSRVDMKMVKDSAFQLSVQPFLGIEIFRIE
                     LSRDTIKVVDRMNKRYMIENYSNLQGQTPIEFNFYNLQALFTNHLFIPGEQGVSRKHY
                     NRFKLNQEGPVAEIKTKDAMGLFYTFKADGEEKLLSTYVADPSDRYALQWLYEDFRLV
                     DRQPFPMLMDVQVLKNGNPEGGVKIHYSRIQLDEPLKLDFSVPSKYKRITFAQVLKTI
                     TNLNQ"
     gene            8217..9536
                     /locus_tag="ACZPB4_11320"
     CDS             8217..9536
                     /locus_tag="ACZPB4_11320"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="murein hydrolase activator EnvC family protein"
                     /protein_id="HIR1098838.1"
                     /translation="MRHVWIVLLALSLSTVVYGQKSAAVRQLEQQRKEALADIEETNK
                     LLQETAQTAKTSLNRLNLLSKQILSRKKVISLLNQELDEIEKDILNIQGQLRTLKREL
                     GDKQTNYGKSMRGLYKRHSSQDKLLFILSAESFSQSMRRMRYLREYADWQKRQANDIV
                     EKQAEISRKQAEMEKTRAEKRALLGTRQEESKKLESEEASQKEEVQLLNKRQKDLKAD
                     LQKKRRQAEALNRQIEKQIAEEIARAEAEAKAARERAERERRAREQAAAKGKPVPESK
                     KEPIREERVADTKGGYAMTKAEKQLSDNFANNRGRLPYPVAGRHTIVATFGEQQHQEL
                     KYVRTSNSGIDIQTSPGADARAVFNGEVTRVFVVPGYNNSVIVRHGNYLTVYSNLSQV
                     YVKAGDRVSTRQAIGRIYSDPEDGNSTILHFQLWKEKTKLNPQPWLE"
     gene            complement(9655..10509)
                     /locus_tag="ACZPB4_11325"
     CDS             complement(9655..10509)
                     /locus_tag="ACZPB4_11325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylinositol-specific phospholipase
                     C/glycerophosphodiester phosphodiesterase family protein"
                     /protein_id="HIR1098839.1"
                     /translation="MKQILSLFITSLALCTACSSPKGSDTVQVAETTTEQTIQKASSA
                     IHYNAFSHNDYWRERPLLDALSFRFNCVEADLWLIDDELYVSHDRPEPNPAITFENLY
                     LKPLVARIQANGGKVYPGSDRPFYLMVDCKAQGEEMYKLLKKQMEPYKEYFCSVDNGE
                     YKEGAVLFFLSGDRPKNSLPKENSRFTFLDGQIKDLGQGIPASLAPVISDNYSDFFTW
                     KGEGEMPADQLQKMREIIRKVHDEGKLFRWWGAPDTEQFKRFFIKEGVDLVGADDLNG
                     LYNVLNKR"
     gene            complement(10591..12219)
                     /locus_tag="ACZPB4_11330"
     CDS             complement(10591..12219)
                     /locus_tag="ACZPB4_11330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MGH1-like glycoside hydrolase domain-containing
                     protein"
                     /protein_id="HIR1098840.1"
                     /translation="MTTRRNFLKQSLLAAGAASVPAGNLLAQEKMEEKRPKYNLPYKN
                     TYLKEPFVTENEFRTAKPETITPGTFEEAKQILPDPTWSGHEKEIEMYWKAWQIGIGN
                     IKAPEPDSGFVCSYLDVAYNGNIFMWDSAFMMMFARFGTRFFPFQRTLDNFYAKQHPD
                     GFICREIKADGADCFERYDPTSTGPNILPWSEIVYYKQFGDIDRLHKIFPALCAYYKW
                     LKLNHTWRNGTYWTSGWGTGMDNMPRVEPKYNPIYSHGHMIWLDVCLQQYFTAGHLLE
                     MGFYLERWQEIEEFEDEQKMLKKYINENLWDEKEHFLFDQYADGSLSSTKGIYAYWAL
                     LTDVLSKERMDAFVAELDNKETFNRLHRVPSLAANHPKYKDNGRYWQGGVWPGANYMV
                     ITGLLQQGYRKLAYEIARNHYDNVLKVYKNTGTFWEYYAPEHEEPGFMARPNFVGWGG
                     LAPISGLIEQIFGIRSNVYEKKLTVDVNLTEAYGIDRYPFGLDGLVAIKVKSRSSATQ
                     EPQVEITSDVPLELTVLWGDKQKTANVKPGTQTV"
     gene            complement(12469..13617)
                     /locus_tag="ACZPB4_11335"
     CDS             complement(12469..13617)
                     /locus_tag="ACZPB4_11335"
                     /EC_number="3.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004035 - alkaline phosphatase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0106219 - zinc ion sensor activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase"
                     /protein_id="HIR1098841.1"
                     /translation="MKRTTLSIITSLAILLSGMIVPEAAAQSRRDKEQTYVLEKPYEV
                     KKLVPPTGKKIKNVILMIGDGMSLMHMYSAWTANRGKLWLDNSQYTGLSKTYCANRLI
                     TDSGAGGTALATGHKTNYHMVGVDPAGKPLESLATLANKKGLSSGIAVTCRLWDATPA
                     DFCCHNTDRDAEAEIVADYVNCGVDYVFGGGSKLFENRADGRDLFKELREKGYQTPRS
                     WEELAKIQKGKVFCVTDTVDTPLPAERGDLLARASMKAIDLLGQNPEGFFLMVEGSQL
                     DDYGHFNDIDLLMQETHDFDRTIGRIFEWAAQDGETLVVVTADHETGGLTLVDGDLDE
                     GRIVCKFSTGSHSGVMVPVYAFGPGAENFTGIFENTDIFWKIKKLLNL"
     gene            complement(13757..16630)
                     /locus_tag="ACZPB4_11340"
     CDS             complement(13757..16630)
                     /locus_tag="ACZPB4_11340"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HIR1098842.1"
                     /translation="MRLIQTLSSCLCTGIIALFTACSQAPQSPIDSVNPFIGTGFHGH
                     TYPGATAPYGAVQLSPDTRKENWDACSGYHYSDSTLMGFSHTHLSGTGCIDLGDILFR
                     PSLQTPLAFSHSDEKASPGYYSVNLREAGVLAELTTTPHVGIHRYTYKKETEATLVVD
                     MDHLLDNEYMYEGWVKRTGDNELTGMRRTRGWVDNQYVFFVAQFSQPFSSMEQPSERQ
                     AVLTFDTTTGKPIVCKVGVSIVNEENARLNLEQETDSYGFDFDAIHQATRSDWEKELD
                     VITVEGGTEAERTNFYTALYHSKIIPNIASDVNGQYRRHDMSVATIPAGRRQFSTFST
                     WDTFRAWHPMMTLLDTTLVNDMVQSLLDMYDASGELPLWPLSAGETGTMIGYHSTSII
                     ADAYLKGIRGYDAEHALEAMKISAEKNKKGADYYIKEGFIPTNIKKESVSCLLEFAYD
                     DWCIAQMAKALGHMDDYETFIKRSQNFINVFDGSTRFFRGKRQDGNWETPFDPFAIGR
                     SYTEATAWQYRFFTPHDVYGLTQLSGGREAFIADLDSLFMVTSEVVGDLVDVTGLVGQ
                     YAHGNEPSHHMAYLYSYVGQPWKTQEWTRRLLDEMYQPTPEGIIGNEDCGQMSAWYIL
                     SSLGFYSVCPGSNQFILTTPLFNKANMKLGNGKTLVITANQPDKNKYITKVTLNGEEI
                     SHCYITYDQLMQGGTLDFTLSATPDKRWGTAPEYAPYSYTEQPTVSIPYIANDLDLFE
                     GEITAELKSTTPEAVIHYTLDGSEPDENAPVYSEPFVLKETTIIKAKGYKKGFVPSRT
                     YSIQATKAVLRPALSIQPTKHGVAYTYYEGEFQWVADLQKAKAVETGTIPEPSILNAK
                     LPDHFGYIFTGYIYAPEDGVYEFSTRSDDGSVLYIGKEKVVDNDASHAAIDAMGRIPL
                     QKGYHPFALHYFEDYEGEYLGWSWRTPSMSTLDAIPTENLYIN"
     gene            complement(16790..18421)
                     /locus_tag="ACZPB4_11345"
     CDS             complement(16790..18421)
                     /locus_tag="ACZPB4_11345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RagB/SusD family nutrient uptake outer membrane
                     protein"
                     /protein_id="HIR1098843.1"
                     /translation="MKRYITVLALSALVCSSCSDFLDVQPEGNATTTSYFLNDQQAID
                     AIDGLYERFHQEGCYGRELFWEQGAACDIVWGRTRGYNSLATLAYTGDESPLRDVFSR
                     MYSTMSRANWIIQELVKKEKGTTLTAVEKRSLGEAYFSRGWAHYLIAYRYGTDKQGVP
                     FVRYEDFPDDYDNSIPPQQATVMDNYKLIIEDMDKAIAYLPNFESYDADNRGRAHQAA
                     AVAFKAKTYAYWATWDATQWNNVIEMVNQLENNYNRDLAPTFAELFSSDLKDYWNAEY
                     LWTIPSIGGALPGGTEFPGIILENKGWGKYNGWGQMKPSYDIYEEMAKDGKGNDRLVR
                     SILEYNQEFPFFGETRKFWSTSDLEAGFMINKYMDAFKYSDPVGEGAVSANGDWPTVR
                     VNFPIIRFAEMLLFRAEAYLMTGQADKATADINRIRLRSNLVPLTGTATMKDLYHERR
                     CELAFEFTDHLFDLKRWNRSSNADIKTLADKELNAHPRIRRYEDRANPVSAFTIIGYE
                     DYTNKNAYQAHMMVFPYPSEEITKSNGQLKQNEGY"
     gene            complement(18463..21711)
                     /locus_tag="ACZPB4_11350"
     CDS             complement(18463..21711)
                     /locus_tag="ACZPB4_11350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SusC/RagA family TonB-linked outer membrane
                     protein"
                     /protein_id="HIR1098844.1"
                     /translation="MKQRLYDFIPVKHLCVGMSLCGIVAGTQTAQASPVFGQSSGLEL
                     PSPSIYQQSTKQISGIVKDQAGIPVIGANVIVKGTTNGVITGLDGDFLLEVPENATLE
                     ISYIGYMTQSIPINGKTTFNIILEEDTQKLDEVVVLGYGAGQRKQDLSASVGVLNNTE
                     DLVARPVTSTESMLQGQLAGVTVQANGGDPTATPSIVIRGQGSQNGDNVLWVVDGVPG
                     APIASMNDIETIVVLKDAASAAIYGAQSGAGGVILVTTKKAKEGKTSLSYDATFGVRK
                     ASNVIEPLNAEEQLEMRKLSYANAGLTLPTGWDLTKNPWVGTTRTNWMDEIFRTAFYQ
                     RHNVALNVGSENASNRVSFAYDNDEGVLINTFNKNLSLRYNGKFKLNKWVTITEDVVW
                     KNNESRSKDTDSGYTGVVAAAMYMPASATVYNPLDGTYGGTTTEDPDYIAKYGSNFAD
                     IHGDAVNPVRLLEAENRYDRTSDIWSTTSLELANIVTGLKFTSRFTYNLKNNLYKNFS
                     PIRDEVGKPSLTNNLDETTYRADAWKTENTLTYDNTFNDMHTVGVLLSTTADHYSKRG
                     LEVNGKDLSDESAYLQYLSYANSVSATDYLTGPDANVSLIARLAYSFNDRYFVTASWR
                     RDYAGRLPKDNNYGDFPAVTAGWKISNESFFPKSETLNLLKIRASWGRVGNLGSIGYN
                     YKSALLGKNYWSEQAQYGVESNKIWGNFVYNSTALNPNLTWETSEQWDLGLDVNMFDN
                     RLSMAFDYFDKRTFNLIQSQTMNWPGTIGIDAMLVNQGEVRNRGFEAQINWNQQVNKD
                     WSYFVSGNFSYLKNWVSDIGVKNADGTPGVWTGITKNDAYFDGSYRNLPYMYQTAEGE
                     PLASFYLIKTDGIFQSDAEAAAYVNKDGKRIQPDAVAGDLKFVDANGDGVINDEDRQY
                     CGSATPKTTFSFSGGFTWKKLSVSAMFQGVGGAQALYVGKYMALSDVEGNFNRSKEIM
                     NAWSPSNTGSNIPRLSKNDPNSNFSTPSDWYLENASYLRLKNFTVSYDLSDVIRKCAH
                     LQERNSMMSVYLSGENLFTITNYSGMDPETGGWDALKYPVSRVFSIGVKLTY"
     gene            complement(21897..>22296)
                     /locus_tag="ACZPB4_11355"
     CDS             complement(21897..>22296)
                     /locus_tag="ACZPB4_11355"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008880 - glucuronate isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HIR1098845.1"
                     /translation="LDQEGLLAKTIVYNLNPRDTELMVANAYNFNDGSVPGKMQYGAA
                     WWFLDQIKGMEDQLNALSSLGLLSRFVGMLTDSRSFLSYPRHEYFRRILCNMLGNEIE
                     KGLLPASELSFIGQMVEDISYNNAKRYFDF"
BASE COUNT         5502 a         5004 c         5833 g         5957 t
ORIGIN      
        1 gagatcgtaa cggaagaatt acgcttgatc gaacgattct tcctcccgat caaacggatc
       61 gtgaaggaag gattttaaag tcgctagggt ccgtcatgca ccttgtttag aactattata
      121 gtttaatagc tgtactgtta aaactaaaaa cttatatttg catgttgata aataagaggg
      181 cgggtgattg tcctaccctt acagtgcaat gatttagatt atgttaaagc aacagttaca
      241 acaaaagtta cagcaaaagc tatcccctca gcagatacag ttgatacggc ttctggagct
      301 tcccgcgatc gagttggaag aacgtgtgaa gcatgagctg gaagataacc cagccttgga
      361 ggaaggaaaa gagcctgttg atgattttga acgaactgaa agcgaggagg ggggagaaga
      421 gatcccttct gttgatactg agaccgacct ttctttggga gattatttaa cggaagacga
      481 tatacctgat tataagctac gggaaatgac cgagcgtgcg gaacggaaag aggatgtccc
      541 cttctccgta agccaatcct tgaatgagtt tctgttacag cagctcgggt taagggattt
      601 accggataag caaatgaaaa tagcggagta tatcattgga aatatcgatg atgacggtta
      661 tttgagacgg gacctttcgg cgatagcgga cgatttgatc ttccaagccg gacaagaggt
      721 agatgagaag gagatcgagt ctatcttgaa tatcatccaa gattttgagc ctgccggggt
      781 aggtgcccgt gacttgaaag aatgtctgtt gatccagctg gataagaagg agaatactcc
      841 ggttacaaat ttggcgattc gtgttttgac cgaatatttc gaggagttca cccgcaaaca
      901 ttacgataag atcttacgag gtctcgatat cgatgaggaa acgttaaaga aggtcattca
      961 cgagattact atgttaaatc cgaaacccgg aagtagttgg ggtggttcta tggaagtggc
     1021 gatgagccag atcatcccgg atttcgtggt ggaagcgcat aatggagagc ttatcttgag
     1081 catgaataac cggggggtac cggatatgcg tatcaaccgg gagtatgccg agatgtttca
     1141 ggattatacg gcgaataagg cgaaccaaac cgctgagagg cgggatgccg tacagttcgt
     1201 gaaacaaaag ttggattccg cccagtggtt catcgacgct atcaagcaac gtaatgagac
     1261 cttgcagcgt accatggagg cgattatcta tttacaacgg gactttttct tgacaggcga
     1321 tgaggctacc ctccatccca tgatcttgaa agacgtagcg gagcgtgcgg gatatgatat
     1381 ctccactatt tcccgggtaa gtaacagtaa atatgtgcaa acgaatttcg gtatttatcc
     1441 gttgaaatac tttttctccg agtctatgca gaccgatacc ggcgaggaga tctcgacccg
     1501 tgaggtgaaa aagatcatga aagagcatgt agatgccgaa gataaacgaa aaccgttgac
     1561 cgatgaggag ttggctacga tcctgaaaga aaaaggatat gtcatcgccc ggcgtacggt
     1621 agcgaaatac agggagcaac tggggattcc ggtagctcgt ctgagaaaag aaatataaaa
     1681 gcgtatgaaa ctattctcga atataatatc cttcgtgttc catccgttgc ttatggtgac
     1741 ctatgggatc gtgttggcgt tgatgtttac atttctcgcc atttacccgt tacctgtgaa
     1801 gctgctgatt gccggaggca cctttatttc gacagcgata gttcccggac ttttcatttt
     1861 cttattggtg aaaaatggcg cggccggcga tatagagctt tccgaccgga aggaacgagt
     1921 ggttccttat ctgattttta tcacttccat cttggtctgt atctttttcc tgtataagat
     1981 gctgatgccg ttttggttgt tggcgatgct gatcggggct tgcgtagcct tggtaatcgc
     2041 cttatgcgtc aatttcgctt ggaagattag cgcgcatgct attggtatcg gcgggttact
     2101 gggcgctatt atgggagtgg cgcgtatcca tatgataaat ccctactggg cttttatagt
     2161 cgtgttgatc gtggccggtt tattaggtac ctcgcgtatc tttttaaaaa ggcatacacc
     2221 aatgcaggta tatgcggggt tttgtctggg atttatatgt acctttgtag cctcattaat
     2281 gagttatatc tatttattca tctaataaaa acactaaaat tatgaatttt cctgcagatt
     2341 taaagtacac aaaagaccat gagtggattc gtgtagaagg tgacgtagct tatgttggta
     2401 ttactgatta tgctcaaggc gagctaggtg agatcgttta tgtagacatt acgacagagg
     2461 gggagaccgt cgctaaagaa gaggtgttcg gtacgattga agctgttaag actgtttccg
     2521 atcttttcat gccggttagc ggagaggttt tggaagtaaa cgctgaattg gaagacgctc
     2581 ctgaattggt taatgaagac gcttatggta aaggttggtt aatcaagatt tctcttacgg
     2641 acgcttctga gttggaggaa ctattatccg ctgaagacta tcaaaaatta atcgctaaat
     2701 aagaatgaca cctgttgtaa gtattatcat gggtagtacc tcggatctac ccgttatgga
     2761 gaaggcggct aagttcttgg atgagatgga gatcccgttc gagatgcatg ctctatccgc
     2821 acaccgtact cccgctgagg tggaggcttt cgccaaagga gctaaaggac gtggaatcaa
     2881 ggttatcatc gccgctgccg gaatggccgc tcatctttgc ggtgtgatcg cttccatgac
     2941 gacagttccc gtgatcggcg tgcctattaa ctctacgttg gacggtatgg atgctctgtt
     3001 ggcgatcgta cagatgcctc cgggaatccc tgtggctact gtcggcatca atggcgcttt
     3061 gaacgctggt atccttgcgg tgcagatgct tgccgttggc gacgagcaac ttcaggagaa
     3121 gctatccgct tataaggagg atttgaagaa gaaaatcgtg aaggctaacg aggagttggc
     3181 taaggtttct tttaaataca aaactaatta attgaaagtt gaaagttgag aattgaaaat
     3241 taaggagaaa gtctctcttt aggttttcag ttctcaacac tcattctcaa ttttcaattc
     3301 tcaattttca atgaacaatg gcttacttta attacaaccg ccgtaaatca tccgttgccc
     3361 aaatcggtga cacacctatg ggaggtgaga atcctatccg tattcaatcc atggctaatg
     3421 tatcaacgat ggatacggag gcggcggtag ctcaagcgat ccgtatgatc gaggcgggag
     3481 ctgagtatgt gcgttttacg gcacaggggg aacgggaagc ccgaaacttg ggcgagattc
     3541 gtaaacaatt gaatgagcaa gggtatacga ctcctttggt cgctgatatc cattttaatc
     3601 ctagagcggc tgatgccgcc gccggtgagg tggaaaaggt acgtatcaat ccgggaaact
     3661 atgtagataa ggtaaagaca ttcagccatc ttgaatatac ggatgaggaa tatgccgccg
     3721 agatcgagag gatccgtgag cggttcgtcc ctttcttgaa tatttgtaag gcacatggca
     3781 ccgctattcg tatcggtgtg aatcatggct cgctctccga tcgtatcatg agccgttatg
     3841 gtgatacgcc cgaggggatg gtagcgagtt gtatggagtt tcttcgcatt tgccgggagg
     3901 agaatttccc agatgtggtt atttcgatta aggcttccaa taccgttgtc atggtaagga
     3961 ccgtgcggtt gttggttcgt acgatggagg ccgagaatat gcattacccc ttgcaccttg
     4021 gggtaacgga ggcgggtgac ggtgaggacg ggcgtatcaa gagcgctgtc ggaatcggta
     4081 cgcttctatg tgacggtatc ggtgatacga tccgggtttc cttgagtgag gaccccgagg
     4141 cggaaatgcc ggtagcgcgt aaattggtgg attatattag ggaacgggaa aatcatcgtc
     4201 ctatcgaggc ttcgatggct cccggtttcg atacggtggc gacaagccgt cgtataagcc
     4261 gtgtggtgga aggtatcgga ggtactttct cgccagtcgt gatctccgat cgtagtagcg
     4321 gggattttga gtttgattat ttgtccttgc cggactatat atatatagga aaggaagatc
     4381 cggataattt gccggataat ttccgtttat tggtagacgc tcatttttgg aaagagcgtc
     4441 cgaatgcttt tccttgcttc atcgcctcgg aggcggagga gttaaaggat tacgattgtc
     4501 cgcttaagtt tatccgtctg acgtatatgg atcttacgga tcgtatgttg gagatcttga
     4561 aagcggataa gaccgtggtg gtcttattaa gtacacatca tcggaatggg gttggctcgc
     4621 aacgtgcggc tatgcataaa ttgctgatgg cgggttgtga cgtgccggtt gtcttgcatc
     4681 gtgatttccg ggagacggat gtggagttgt tgcaactgaa atccgccgcc gatttcggaa
     4741 cgcttttgct ggatggtttc ggggatggct tgatgctgca caatgaggga tgcgaggcgg
     4801 ttgtctcgga tcgctgtatg ttcgggatct tgcaggctac aagaacccgt atcagtaaga
     4861 cggaatatat ctcttgtccg agttgcggac gtaccttgta cgacctgcaa acaacgatcg
     4921 cccgtatcaa ggaggctact tcccatttaa aaggcttgaa gatcggtatc atgggctgta
     4981 tcgtgaatgg tcccggcgag atggccgatg ccgactatgg ttatgtgggt gccggacgtg
     5041 gacaaatcag cctgtataaa ggtaaggaat gtgtcctcaa gaatatcccc gaggaagacg
     5101 ctgtagaacg tttagttcag ttaataaaag agaacgggga ttgggttaat tgattgacta
     5161 ttgacaattt gtttatcttt gcaagtatga aagtaagaat tatcaataaa tcgcatcacc
     5221 cgctgccggg ttatgcgact cctttatctg ccgggatgga tatccgggcg aatttgtcgg
     5281 aatcggttgt gttgaaaccg ttggaacgta aattaatccc gaccggactt tatatctcgc
     5341 tgccggaagg ctatgaggcc cagatgcgtc cgcgtagcgg gctggcttta aagcatggga
     5401 taaccctgct gaatacgccg ggtacgatcg acgccgatta tcggggggag atcggtatca
     5461 ttctcgtgaa tctatcttcc gagcctttta cggtgaatga tggtgagcgt atctgccaaa
     5521 tggttatagc cgctcatagc catgtggatt gggaacccgt ggagacgttg gatgatacgg
     5581 agcggggagc cgggggattc ggtcataccg gaaaagaata agaataataa ggttaacaag
     5641 aataatagga tgtttaagca actgatatat ctcatctctt tcctctcgtt ggtcgctgtg
     5701 ctcccggctg gtgctacaga aacggagaag gatcaacgta agttcgatta cttcttttat
     5761 gagggcttga acttgaagaa cgccgggaaa ttcgacgccg cttatgatgc cttcaaccat
     5821 tgcttggaga ttgactctac ggcggctccg gtcttgtatg agctttcttc tttttatgta
     5881 cagttgaacc gtccggagaa agcggtcgag atgttgaaaa gagccgtggc caacagcaag
     5941 gataatttca cgtataaaat ggcattggcg tctatcaccc ggaatctggg catgtatggc
     6001 gaagccgccg aggagtacga ggaattggtt cgtgattatc cggagaagga ggagctgaat
     6061 tattatctgg ccgatgcctt gacgcaagcc ggcgagatcg ggaaggcgat cgaggcttat
     6121 gatgcgttgg agtcggttat gggtatgaac gaggcgatct ccatgcagaa atacaaactg
     6181 tacgtccagt tggagaaacc ggaagaggct ttcaaggaga tcgagaagct agcggctaaa
     6241 tatcctatgg aggcccgtta ccagatcgta ttgggcgatc ttcatttgga aaacggggag
     6301 atggacaagg ctttggcttg ctatcaaaaa gcgaatgaga ttgatccgac cgacccttat
     6361 tatatcgtct ctatggccaa ttactacgag gcgaaagggg ataaggaggc cgccgagcaa
     6421 caaatccgca gcgctttggt aaacgagaag ctggacgtgg agacgaaagt gaacatcctt
     6481 tcccggtata tcttgaaact gcaacaaacg aagcaaggaa ctgagaatgc gaaccattta
     6541 ttccaaactc ttttggagca acatccggag gatatcgact taaaactgat gtatggcggt
     6601 ctcttgatgg cccaaggaaa gacagaggag gcgaaattcc agttccagtt ggtaacagag
     6661 atggaaccgg gtaacgccgg ggcttggcag caattgctga atctggcttt gaaaggggag
     6721 gatatcccgg aggtcatccg tatctgtacg gcttgtatgg agcttttccc cgagtcgccg
     6781 gaatattact tctatctggg tatcgcttac taccaacaac agaaatatca agaagccttg
     6841 aatacctatt atgcgggctt gaatatcatt ccgaaggaga acctgccgct gaaatcggat
     6901 ttctacggtc agatcggtga tatttattac cagatggggc aattggatca agcgtataaa
     6961 gcgtacgatg aggcgttgaa gtataatgac aagaacgtgg tcgtactgaa caactacagt
     7021 tacttccttt ctttggagaa gaaagacttg aaaaaggcgg aacgtatgag cgcccaatgt
     7081 atcaagctgg aaccggacaa cgccacgtat ctggatacct acgcttggat cttcttcgta
     7141 caaggaaact ataccttggc gaaaatctat atcgagagcg ctttggagaa agataagaca
     7201 aagagcgccg aactcgtgga tcattatggg gacatccttt tcatgaacgg tgataaggaa
     7261 aaagcggtgg agcaatggaa aaaggcgaaa gagatgggga aggattccga gatcttgaac
     7321 cgtaagatcg ccgagcaaca atatatagaa gacgagaacg cgaaatgaaa agagactatt
     7381 tcttgacctt cctgttatgt ggaggtcttt tactttcgat gttgacaggc tgtaaatcgt
     7441 ccaagaaagt cgggacggtg gaatccgcta gcgtgaaggc tcataatgag ttcttccagt
     7501 cggtggagga tcaatccttc cagttccgta ccttgacggc ccggttgaac gtggatctgg
     7561 atatccctgg taagcaaatg agctctcggg tggatatgaa gatggtcaag gatagtgctt
     7621 tccaactgtc ggtacaacct tttctcggga tcgagatctt ccgtatcgag ttgagccggg
     7681 atacgatcaa ggtggtagac cgcatgaata aacgctatat gatcgagaat tattccaatt
     7741 tgcaagggca gactccgatt gagttcaact tctacaattt gcaggctctt ttcacgaatc
     7801 atctgtttat cccgggggag cagggcgttt cccgtaagca ttataatcgt tttaagctga
     7861 atcaagaagg cccggtagcc gagatcaaga ccaaggatgc catggggctt ttctatacct
     7921 ttaaggcgga tggcgaggag aaacttctct ctacctatgt agcggatcct tccgatcgtt
     7981 atgccttgca atggttgtac gaggattttc gcttggtgga tcggcagccg ttcccgatgt
     8041 tgatggatgt gcaggtgttg aagaacggga atcccgaggg tggggtgaag atccattact
     8101 cccgtatcca actggacgag ccgctcaagt tggatttttc ggttccttct aaatataagc
     8161 gtattacctt tgcgcaagta ttgaaaacga ttacgaatct gaatcaataa tctatcatga
     8221 ggcacgtctg gatcgttcta ttggcattgt ctttatctac cgtggtttac ggtcagaaat
     8281 ccgccgctgt ccgtcagttg gagcagcagc gcaaggaggc gttggccgat atcgaggaga
     8341 cgaataaatt attgcaagag acggcccaga ctgctaaaac ttccctgaac cgtttgaatc
     8401 tactctccaa acaaattctt tcccgtaaga aagtcatcag tttattgaat caagagctgg
     8461 atgagatcga gaaagatatc ttgaatatcc aaggccagtt gcgcacctta aaacgggaac
     8521 tgggcgataa gcagacgaat tacggtaaat cgatgcgagg gctttataaa cgccatagct
     8581 cgcaagataa attgttgttt atcctatccg ccgagagttt ctctcaatcc atgcggcgta
     8641 tgcggtattt gcgggaatat gcggattggc agaagcggca agcgaatgac atcgttgaaa
     8701 agcaggccga gatcagccgt aagcaagctg agatggagaa gacccgtgcc gagaaacgtg
     8761 cccttttagg aactcgtcaa gaagagagta agaagctaga aagtgaggaa gcttctcaga
     8821 aagaggaagt ccagctattg aataagagac aaaaggattt gaaggcggat ctccaaaaga
     8881 agcgtcgtca agccgaggct ttaaaccgac agatagagaa gcagatcgcc gaggagatcg
     8941 cccgtgccga ggccgaggcg aaagccgccc gtgaacgtgc ggaacgtgag cgtcgtgctc
     9001 gtgaacaagc tgccgctaag ggtaaacccg taccggaaag taaaaaagag ccgatccgtg
     9061 aggaacgtgt ggcggatacg aaagggggct atgcgatgac aaaggcggag aagcaattgt
     9121 ccgataactt cgccaataac cggggacgtt tgccgtatcc ggtggccgga agacatacga
     9181 tcgtcgctac attcggcgag caacagcatc aggagttgaa atatgttcgt accagtaata
     9241 gtggtatcga tatccagacc tcacccgggg cggatgcccg tgcggtattc aatggggagg
     9301 tgacgcgtgt gttcgtggtg ccggggtata ataattccgt aatcgttcgt catggtaact
     9361 acttgacggt ttatagcaat ttgagtcagg tatatgtaaa agcgggcgac cgggtctcta
     9421 cccgtcaagc gatcggaagg atctattcgg atccggagga cggtaattcc acgatcctcc
     9481 atttccaatt gtggaaggaa aagacgaagc tgaatccgca gccttggttg gaataaaagc
     9541 ggttgtgata tgttaaaact atgatgggca ttataaggct gttacgatgc ctgttgtaaa
     9601 gatgctagaa tgcccattgt aacaacctta taatgcctat tgtaattttc tcgtttaacg
     9661 cttgttcaat acgttgtata acccattcag gtcatcggca cctaccaagt ctacgccttc
     9721 tttgatgaag aagcgtttga actgctcggt atccggggcg ccccaccaac ggaatagttt
     9781 tccctcatcg tggactttcc ggatgatctc acgcatcttc tgtagttggt cggcgggcat
     9841 ctcaccttcg cctttccatg tgaagaaatc ggagtaatta tcgcttatga ccggagcgag
     9901 ggaagcaggg atgccctgtc ccagatcctt tatttgtccg tcgaggaagg tgaagcggct
     9961 gttctctttc ggcaggctgt tcttcggacg gtcgccggaa aggaagaaga ggacggcacc
    10021 ttctttatat tcgccgttat cgacggaaca gaaatattcc ttgtaaggtt ccatctgttt
    10081 ctttaatagc ttgtacatct cttcgccttg tgccttgcaa tccaccatca ggtagaaagg
    10141 acgatcgcta ccgggataga ccttacctcc attcgcttgt atgcgggcca cgagcggctt
    10201 gaggtatagg ttctcgaagg taattgccgg attgggttcc gggcggtcat gggaaacgta
    10261 tagctcgtca tcgatcagcc acagatcggc ctccacgcag ttgaagcgga aggacaaggc
    10321 gtccagcaga ggtctctccc gccagtaatc attgtgcgag aaggcgttgt aatgaattgc
    10381 ggaggaggct ttctgaatcg tctgctccgt ggttgtctcc gccacttgaa ctgtgtccga
    10441 tcccttcggg gaggagcaag ccgtacagag ggcgagggag gtgataaata aggatagaat
    10501 ctgtttcata tactaattgt tttttgagtc tagttgtaga gacggggcgt gccccgtctc
    10561 tacaactgga tgtttgatgg atttactgtt ttatacggtt tgcgtgccgg gttttacgtt
    10621 agccgtcttc tgtttgtcgc cccaaaggac ggttagttcc aagggaacgt cgctggtaat
    10681 ttctacctgc ggctcttggg tagcggaaga acgggacttg actttgatcg ctaccagacc
    10741 gtcgaggccg aaaggataac ggtcgatacc ataagcctcc gtcaagttca cgtctacggt
    10801 caatttcttc tcgtacacat tggagcggat gccgaagatt tgctcgatca agccggagat
    10861 cggtgccagt ccgccccagc ccacgaaatt cgggcgagcc atgaagcccg gctcctcatg
    10921 ttccggagcg tagtattccc agaacgtacc ggtattctta tacaccttta ggacgttatc
    10981 gtaatggttg cgtgcgatct cgtaagccaa tttacgatag ccttgttgca ataggccggt
    11041 aatcaccata tagttcgctc ccggccatac gccaccctgc cagtagcggc cgttatcctt
    11101 gtatttagga tggttggcgg caagggaagg gacgcggtgc aggcggttga atgtctcctt
    11161 gttatccagc tcggccacga aagcatccat gcgttccttg gacaggacat cggtcaataa
    11221 ggcccagtac gcgtagattc ccttggtgga ggaaaggctt ccgtcggcgt attgatcgaa
    11281 aaggaaatgt tccttctcgt cccataggtt ctcgttgata tacttcttta gcatcttctg
    11341 ctcgtcctcg aactcctcga tctcctgcca acgctccaga tagaaaccca tctcaagcag
    11401 atgcccggca gtgaagtatt gttgcaagca aacgtccagc cagatcatat ggccgtggct
    11461 gtatatcgga ttgtatttcg gttccacccg gggcatgttg tccatgccgg taccccaacc
    11521 gctggtccaa tacgtaccgt tgcgccacgt atggtttagc ttcaaccatt tataataagc
    11581 gcaaagggcg gggaatatct tgtgtaggcg gtctatatcg ccgaactgct tataatagac
    11641 gatctcgctc caagggagga tattcggtcc ggtgctggtc ggatcgtaac gctcgaaaca
    11701 gtccgctccg tctgccttga tctcccggca gataaaaccg tccggatgtt gtttggcgta
    11761 gaaattatct aacgtacgtt ggaaggggaa gaagcgggta ccgaaacggg cgaacatcat
    11821 catgaaggcg gagtcccaca tgaagatatt gccgttgtag gcgacatcga ggtagctgca
    11881 tacgaaaccg gaatccggtt ccggggcctt gatgttgccg atgccgattt gccaagcctt
    11941 ccagtacatc tcgatttcct tctcgtgtcc gctccaagtc gggtccggga ggatttgctt
    12001 ggcctcctcg aaggttccgg gcgtgatggt ctccggtttc gctgtccgga actcgttctc
    12061 ggtcacgaag ggttccttca ggtaggtgtt cttgtaagga agattgtact tgggtcgttt
    12121 ctcttccatt ttctcttgcg ctaaaaggtt cccggcggga acggaggccg cacctgccgc
    12181 aagaagggat tgctttaaga agtttcgtct tgttgtcatt ctttatgata tttattgggg
    12241 gagagaggga gaaggcgcgc ctcagtcggt gaacacggtc ctcccggccg ggtaccgtag
    12301 tactgctagt caagtactgc tgtcctgcta gtcaagtacc gctgtcctct cagccaaagt
    12361 actgcggtac ttgggcaggg gtactgcgtt accctaccgg gaggattgcg gtacttgact
    12421 agcgggatag cggcctgtta tactctccat cggatgaata ctgtttgatt atagattcag
    12481 gagctttttg atcttccaga agatatccgt attctcgaag atacccgtga agttctcggc
    12541 acccgggccg aaagcataaa cggggaccat tacgccgcta tggctaccgg tagagaactt
    12601 acaaacgata cggccctcgt ccagatcccc gtctaccaag gtaaggccac cggtctcgtg
    12661 atcggcggtt acgacaacca atgtctcacc gtcttgggcg gcccattcga agatacgtcc
    12721 gatcgtacgg tcgaaatcat gtgtctcttg catcaacagg tcgatatcgt tgaaatgtcc
    12781 gtaatcatcc aattgggagc cctctaccat caggaagaaa ccttccgggt tttgtcccaa
    12841 cagatcgatc gctttcatcg aggcacgagc caagagatcg cctcgctcgg cgggaagcgg
    12901 ggtgtctacg gtatcggtaa cgcagaatac cttgcctttt tgaatcttcg ccagttcctc
    12961 ccagctacgg ggagtctggt aacctttctc ccttaattcc ttgaacaaat cgcgaccgtc
    13021 cgcacggttc tcgaatagct tggagccgcc gccgaatacg taatcgacgc cacagttcac
    13081 gtaatccgct acgatctcgg cctcggcgtc gcgatccgta ttgtggcagc agaagtcggc
    13141 gggcgtagcg tcccataggc gacaggtaac ggcgatgccg cttgacaggc ctttcttgtt
    13201 cgccaaggta gccagagatt ccaagggttt gcctgccggg tctacgccta ccatatggta
    13261 gttcgtttta tggccggtgg ccagtgcggt acctccggct ccggagtcgg tgatgaggcg
    13321 gttggcgcaa taggttttcg agaggccggt gtattgggag ttgtccagcc agagcttgcc
    13381 ccggttggcg gtccaagcgg aatacatgtg cataaggctc atgccgtcgc cgatcatgag
    13441 gatcacgttc tttattttct ttccggtagg ggggactagt ttcttgacct cgtaaggttt
    13501 ctctagtaca tacgtttgtt ctttgtctcg gcgactttgt gccgcggcct ccggaacgat
    13561 catgccggat agcaggatgg ctaaggaggt gatgatcgat aaggttgttc ttttcatatt
    13621 ctttgttgtg ttaatattta tatcttatct agttgtagag acggggcgtg ccccgtcttc
    13681 cactgtctga tagtaattag aataccattt tgaggggatg agacggggca cgccccgtct
    13741 ctacaactaa gtattatcaa tttatataaa ggttctctgt tgggattgcg tctagtgtgg
    13801 acatgcttgg cgtacgccag ctccagccta ggtattcacc ctcgtaatcc tcgaaataat
    13861 gcaaggcgaa ggggtggtag cctttttgta aggggatgcg tcccatcgcg tcgatggcgg
    13921 cgtgggaggc atcattgtcc actacctttt ctttgccgat gtagaggacg ctaccgtcat
    13981 ccgagcgggt actgaactca tagactccat cttccggggc gtatatatat ccggtgaaga
    14041 tataaccgaa atgatccggc aatttagcgt tcaggatgga aggctcaggt attgttccgg
    14101 tctcgaccgc cttcgctttt tgcagatcgg ctacccattg gaactctcct tcgtaataag
    14161 tataagctac cccatgcttc gtaggctgta tggataatgc ggggcgtaat acggcttttg
    14221 tcgcttggat cgagtacgta cggctgggta cgaatccctt tttatatcct ttggccttga
    14281 tgatcgtggt ctcttttaag acgaatggct cgctgtatac cggagcgttc tcatccggtt
    14341 ccgatccgtc aagcgtgtaa tggataaccg cctcgggtgt cgtggatttt agttccgccg
    14401 taatctctcc ttcaaacaaa tccagatcat tcgctatgta agggatagag acggtaggtt
    14461 gctccgtata ggaataggga gcgtactcgg gagcggttcc ccaacgcttg tccggtgtcg
    14521 ccgagagcgt aaagtccagc gtcccccctt gcatcaactg gtcgtaggtg atgtagcaat
    14581 gcgatatctc ctcgccgttt aaggtaacct tcgtgatata cttgttctta tccggctggt
    14641 tggcggtaat gaccaatgtc ttgccattgc ccagcttcat gttcgcctta ttgaacaacg
    14701 gggtcgttag gataaactgg ttgctacccg gacatacgga gtagaagccg aggctgctca
    14761 agatatacca agcggacatc tggccgcaat cctcattgcc gatgatgcct tccggcgtgg
    14821 gctggtacat ctcgtccagc aagcgacggg tccattcctg tgtcttccag ggctggccca
    14881 catagctata taggtaagcc atgtggtggc taggctcgtt gccatgcgca tattgaccga
    14941 ccaatcctgt aacgtctacc agatcgccga ctacctcgga ggtaaccata aataagctat
    15001 ccagatcagc gatgaacgcc tcccggcctc cggacaactg ggtcaatcca tatacgtcat
    15061 gtggggtaaa gaaacgatat tgccaggccg tagcctccgt ataggaacgt ccgatggcga
    15121 atggatcgaa aggtgtctcc caattcccat cctgccgttt gccccggaag aaccgggtac
    15181 taccgtcgaa tacgttgata aaattctggg agcgcttgat gaacgtctca taatcatcca
    15241 tatgtcctaa agctttcgcc atttgtgcga tacaccaatc atcgtaggcg aattccaata
    15301 ggcaggaaac cgattctttc ttgatattcg tcgggatgaa gccttccttt atataataat
    15361 ccgctccttt cttattcttc tcagcggaga tcttcatcgc ttcgagagcg tgttccgcgt
    15421 catatccgcg aatacctttt aaataagcgt ccgctataat cgatgtggag tgataaccga
    15481 tcatggttcc ggtctcgcct gccgataagg gccataacgg aagctcgccg ctggcgtcgt
    15541 acatatccaa gagagactgt accatatcat tcaccaaggt agtatccaac agagtcatca
    15601 tcggatgcca ggcccggaag gtgtcccaag tggagaaggt ggagaattgg cggcgacctg
    15661 ccgggatcgt cgctacgctc atgtcgtgac ggcggtattg tccgttcacg tcgctcgcta
    15721 tattcggaat gatcttgcta tggtatagcg ccgtgtagaa attcgtgcgc tcggcttcgg
    15781 tgcctccttc taccgtgata acgtccagct ctttttccca atcggaacgt gtcgcttgat
    15841 ggatggcatc gaaatcaaag ccataggaat ccgtctcttg ctcaaggttc agacgggcgt
    15901 tctcctcatt tacgatcgat accccgactt tgcagacgat gggctttccg gtagtcgtat
    15961 cgaaggtaag tacggcttgc cgttcggaag gctgttccat ggaagagaag ggttgcgaga
    16021 actgcgctac aaagaagaca tattgattgt ctacccagcc ccgggtacgc cgcataccgg
    16081 taagctcgtt atccccggtt cgcttcaccc agccctcgta catatattcg ttatccaata
    16141 aatggtccat atcgaccacc aacgtagcct ctgtctcttt tttataggta tatcggtgta
    16201 tcccgacatg cggggtcgtg gtaagttccg ctaatacacc tgcctccctg agattcaccg
    16261 agtagtaacc cggggaagcc ttctcgtccg agtgcgagaa cgctagaggt gtctggagtg
    16321 acggacggaa taggatatcg ccaaggtcga tacatcccgt accgcttaaa tgggtatggg
    16381 aaaaacccat taaggtagaa tcgctgtaat gataaccgga acaagcgtcc caattctctt
    16441 tccgggtgtc cggactgagt tggaccgctc cgtaaggagc cgtggccccg ggatacgtgt
    16501 gtccgtgaaa tcccgtgccg ataaacggat tcacggaatc gatgggggat tgtggtgctt
    16561 ggctacaggc cgtgaataag gctattatcc ctgtacacaa gcaagaagaa agagtttgaa
    16621 ttaatctcat ggtgtatctt ttgtttacta tattatacaa ttggcaaagg taaactacct
    16681 atttgagata tgcgttttta cccggtagaa aataacacgg gctgtttcat tttctgagac
    16741 agcccgtaat tgaatcttat tcgtaccttg atcggtttaa aggagccggt taatatccct
    16801 cgttctgctt cagttgacca ttcgatttag taatctcttc acttggatac gggaatacca
    16861 tcatatgtgc ttgataggcg tttttgttgg tgtaatcttc gtaaccaata atcgtgaacg
    16921 cggataccgg attcgcccgg tcttcatatc tgcggatacg tggatgtgcg ttcaactctt
    16981 tatcggccaa tgtctttatg tcggcattgg aagaacggtt ccaacgcttt aagtcgaata
    17041 gatggtctgt aaactcaaaa gccaattcac aacggcgttc gtgatataga tccttcatcg
    17101 tggcggtgcc ggtaagcggt accaagttgg agcgtaggcg gatacggttg atatctgcgg
    17161 ttgctttatc ggcttggcct gtcattaaat atgcctcggc acggaacaat aacatttctg
    17221 cgaaacggat gatcgggaaa ttgacacgga ccgtaggcca gtctccgtta gcactcacgg
    17281 ctccttcacc tacagggtct gagtatttga acgcgtccat gtatttattg atcatgaaac
    17341 cagcttcaag gtcggaggta gaccagaact tgcgtgtctc gccgaagaac gggaactctt
    17401 ggttgtattc caagattgag cgtactaaac ggtcattacc tttaccatct ttcgccattt
    17461 cttcgtagat gtcgtaagag ggcttcatct gcccccaacc attatatttg ccccagcctt
    17521 tgttctcaag gataataccc gggaattcgg taccgcccgg tagtgcgcca ccgatactcg
    17581 gaatagtcca gagatattcg gcgttccaat aatctttcaa gtcagacgag aatagttctg
    17641 cgaatgtggg agctagatct cgattgtagt tgttctctaa ttgattgacc atctcgatga
    17701 cgttgttcca ttgggtagca tcccaagtag cccagtaagc ataagttttc gctttgaacg
    17761 ccacggcagc agcctgatgt gcccggcccc ggttgtcagc gtcataggat tcgaagtttg
    17821 gaaggtaggc gattgccttg tccatatctt cgatgatcag tttataattg tccataacgg
    17881 tagcttgctg aggcggtatg gagttgtcgt aatcgtcggg gaagtcctcg taacgtacga
    17941 aaggcactcc ttgtttatcc gtaccgtacc gataagcgat cagataatgt gcccaaccgc
    18001 gactgaagta agcttcgccc aagctgcgtt tctcgacggc ggtcagcgtc gttccctttt
    18061 ctttcttcac taattcttgg atgatccaat tcgcacggga cattgtagaa tacatacggc
    18121 tgaatacatc tcttagagga gattcatcac cggtataggc taaggtcgcc aaagagttat
    18181 aaccacgcgt acgtccccaa acaatgtcgc atgcggctcc ctgttcccag aataattcac
    18241 ggccgtaaca accttcttga tggaatcttt catataatcc gtcaatggca tcaatggcct
    18301 gttgatcatt caagaaatag gaggttgtag ttgcgtttcc ttccggctga acgtcgagga
    18361 agtcgctaca agaactacaa accaatgcgg ataatgctaa tactgtaata tatcttttca
    18421 ttttgatcct ttgttaatat gaatatcttt taaaacaccc gattagtatg tcaatttgac
    18481 tccgatagag aatacgcgtg aaaccggata cttcaaggca tcccaaccgc cggtttccgg
    18541 gtccattcct gagtagttcg tgatcgtgaa gagattctca ccgctaaggt aaaccgacat
    18601 catgctgttg cgttcttgca ggtgagcgca tttccggata acatcactca agtcatagga
    18661 tacggtgaag ttcttcaaac gcaagtaaga agcattctcc agataccaat cagatggtgt
    18721 gctaaagttg ctattcgggt cgtttttcga taagcgtgga atattcgatc ctgtattcga
    18781 cggactccaa gcgttcatga tctcttttga gcggttgaag tttccttcta catcacttaa
    18841 ggccatatat ttacctacat ataaagcttg tgctccacct acgccttgga acatagcgct
    18901 tacggaaagc ttcttccaag tgaatcctcc ggagaatgag aatgtagttt taggtgtagc
    18961 gctaccgcag tattgacggt cttcatcatt gatgactcca tcaccattgg catcgacgaa
    19021 tttcaaatcg ccggctacag cgtccggttg gattcgtttt ccgtctttgt ttacataagc
    19081 ggctgcctct gcgtcgcttt gaaaaatgcc gtcagtcttg atcagataga aagaggccag
    19141 cggttctcct tcggctgttt gatacatata tggaaggtta cgataactac catcgaaata
    19201 tgcatcattt ttggtgatac ctgtccaaac gcccggagtt ccgtctgcgt tctttacgcc
    19261 aatatcagaa acccagttct ttaaataaga gaagtttccg gaaacgaagt acgaccaatc
    19321 tttatttacc tgttggttcc aattgatttg cgcctcgaaa cctcggttgc ggacttcacc
    19381 ttgattgact aacatggcat cgataccgat cgttcccggc cagttcatcg tttgcgactg
    19441 gatcaagttg aacgtgcgtt tgtcgaaata gtcgaatgcc atgctcaagc gattgtcgaa
    19501 catgttcaca tctagaccta agtcccattg ctcggaagtt tcccatgtta agttgggatt
    19561 taatgcggta gagttataga cgaagttacc ccaaatcttg ttcgattcta cgccgtactg
    19621 tgcctgctcc gaccaataat tcttacctaa taaagctgat ttgtaattgt aaccgataga
    19681 tcctagatta ccgacacgtc cccaagaagc acggatcttc aataaattca gtgtctcgct
    19741 cttcgggaag aaagattcat tagagatttt ccatccggct gttacggcag ggaagtcgcc
    19801 atagttatta tctttaggta gacggcctgc gtaatcacga cgccaagagg ctgtaacgaa
    19861 gtaacgatcg ttgaaggaat aagccagacg ggcgatcaag gatacgtttg cgtcaggacc
    19921 ggtcaaataa tcggttgcgg aaacggaatt cgcataggat agatattgta aataagcgga
    19981 ttcgtcagat aaatcttttc cattaacctc taatcctcgc ttgctgtaat gatcggccgt
    20041 agtggatagt aagacaccca cggtgtgcat gtcattaaac gtattgtcgt aagtcaatgt
    20101 gttttccgtt ttccatgcgt ctgcacggta agtcgtttca tccagattat ttgtcaagga
    20161 gggttttccc acctcgtcac ggatcgggct gaagttctta tatagattat tcttcaggtt
    20221 gtaagtgaaa cggctcgtga acttcaagcc ggtaacgata ttagctagtt ccagactggt
    20281 cgtactccag atgtcgctgg ttcggtcata gcggttttcc gcttccagca agcgaaccgg
    20341 attgacagcg tctccatgga tatctgcgaa gttggagcca tatttggcga tgtaatccgg
    20401 gtcttcggtc gttgttccac cgtaagtgcc atccagcgga ttgtaaaccg tagcgctggc
    20461 aggcatatac atagccgccg cgacaactcc cgtataacca ctgtcggtat cttttgaacg
    20521 gctttcgttg tttttccaaa ccacgtcttc ggtgatagtc acccatttat tcaatttgaa
    20581 tttaccgttg taacgaagtg aaaggttctt gttgaaagta ttgatcaata caccttcatc
    20641 attatcgtaa gcaaatgaaa cacggttgga ggcattctct gaaccaacat tcaaggctac
    20701 gttatggcgt tggtagaaag cggtgcggaa tatttcatcc atccagttgg tacgtgtggt
    20761 acctacccat gggttcttgg tcaagtccca accggtcggc aatgtaagcc ctgcgtttgc
    20821 gtaagacagt tttcgcatct cgagttgctc ttccgcattt aacggctcga ttacgttgct
    20881 agctttacga acaccgaaag tcgcgtcata gctcaacgag gtcttgccct ctttcgcctt
    20941 cttggtggtt accaagataa cacctccggc tccggattgc gctccataga tagcggcgga
    21001 ggcagcatct tttaagacga caatcgtctc gatatcattc atagaagcga tgggtgcgcc
    21061 ggggacaccg tcaacaaccc ataatacgtt atcgccattc tgtgagccct gtccacggat
    21121 cacgatcgag ggtgtagctg tcgggtctcc accgttcgct tgtacggtaa cacccgctaa
    21181 ctgcccttgc aacatacttt cggtagaggt aaccggacgg gccaccaggt cttccgtgtt
    21241 gttcagcacg cccacggaag cggagagatc ttgtttgcgt tgccccgctc cataaccgag
    21301 tacgactacc tcatccaatt tctgcgtatc ttcttctagg atgatgttga aggtcgtttt
    21361 cccgtttatc gggatacttt gcgtcatata accgatataa ctgatctcta aggtagcgtt
    21421 ttccggaact tccagtagga aatctccatc gagcccggtg attactccgt ttgtcgtccc
    21481 ttttacgatc acgttcgcgc caattacagg aatccccgcc tggtctttga cgataccgga
    21541 aatctgtttc gtactttgtt ggtagatgct gggactcgga agttctaagc ccgatgattg
    21601 cccgaagacg ggagaagctt gagcggtttg ggtacctgcc actatgccac ataaagacat
    21661 ccctacgcat agatgcttga cagggatgaa atcataaagc cgttgtttca tgtttgcgta
    21721 ttttagtgtt tatctaaatc tgccgcaaaa gtaggcgtaa tatgtgcgag tatagtggaa
    21781 ggtcttatga agtgtttgtg aataaaatgt tgcaaagctg ttgcagcctt actgcaacgc
    21841 acgtgcagtg ttactgcgac aggcgtgcag taacattgca atgcgggttg caataatcag
    21901 aaatcaaagt atcgtttagc gttgttgtaa ctgatgtcct ccaccatctg tccaatgaag
    21961 gaaagctcgg aggcgggcaa taagcctttc tctatctcat tgcctagcat attacaaagg
    22021 atccggcgga aatactcatg gcggggatat gacaggaagc tgcgggaatc tgtcagcata
    22081 ccgacgaaac ggcttaaaag accgaggctg gaaagtgcgt ttaactgatc ttccatgcct
    22141 ttgatctgat cgaggaacca ccaagccgct ccatattgca tcttcccggg tacactgccg
    22201 tcgttgaaat tgtaggcatt ggctaccatc aactcggtgt cgcggggatt caggttgtaa
    22261 acgatcgttt tcgctaacag cccttcttga tctaaa
//
LOCUS       DBMDTB010000068        21974 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_803_length_21974_cov_10.562931, whole genome shotgun sequence.
ACCESSION   DBMDTB010000068 DBMDTB010000000
VERSION     DBMDTB010000068.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 21974)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 21974)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21974
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_803_length_21974_cov_10.562931"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..817)
                     /locus_tag="ACZPB4_11360"
     CDS             complement(<1..817)
                     /locus_tag="ACZPB4_11360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase dimerization/phospho-acceptor
                     domain-containing protein"
                     /protein_id="HIR1098846.1"
                     /translation="MSCYYCELYTMKGNSGKAQAYLDQATAYLDSSFGDRVEAQYLRT
                     KSFYYWKEKDYRHALSAVNLALKINRDLDKLEMKKAILQSSGQLQEAVTIYEEIINKT
                     ETINTDAFDRQIEQLRVLNDLNDLEKQDRELKLKSEQEALKQKQIVVSIGLLLVLMGL
                     LYMLWRIYMHTKRLRNELLQEKDSLTASEKQLRVVTKEAEAANKKKSAFIANISHEVR
                     TPLNAIVGFSELLASSEYSEVEKIRFAGEVNHSSELLLNLVNDVLDLSRLESGK"
     gene            complement(894..1355)
                     /locus_tag="ACZPB4_11365"
     CDS             complement(894..1355)
                     /locus_tag="ACZPB4_11365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098847.1"
                     /translation="MRGKNIHLGRVGCNYGKLLIFIDIYFVSLRIVSDKSMSRGFLRK
                     SSVNTFIGIVWILFAVGTSAQNAVSKFRADSIRQSLSRIQKPQDKIPLLKELIGLYWQ
                     LPEEVPALKEIIDIAMPLDSIGIVYDAMAGLSRYYPAIRTFVRVGGALETV"
     gene            1465..3255
                     /gene="rpsA"
                     /locus_tag="ACZPB4_11370"
     CDS             1465..3255
                     /gene="rpsA"
                     /locus_tag="ACZPB4_11370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HIR1098848.1"
                     /translation="MENLKNIQPVEDFNWDAFEQGETYTEVSKDDLVKTYDETLNTVK
                     DKEVVMGTVTSMNKREVVVNIGFKSDGVVPMSEFRYNPDLKIGDEVEVYIESQEDKKG
                     QLILSHKKARATRSWDRVNEALEKDEIIKGYIKCRTKGGMIVDVFGIEAFLPGSQIDV
                     KPIRDYDVFVGKTMEFKIVKINQEFKNVVVSHKALIEAELEQQKKDIISKLEKGQVLE
                     GTVKNITSYGVFIDLGGVDGLIHITDLSWGRVSHPEEIVQLDQKINVVILDFDDEKKR
                     IALGLKQLTPHPWDALDTNLKVGDKVKGKVVVMADYGAFIEIAPGVEGLIHVSEMSWT
                     QHLRSAQDFMKVGDEIEAVILTLDRDERKMSLGIKQLKADPWENIEERFPVGSRHAAK
                     VRNFTNFGVFVEIEEGVDGLIHISDLSWTKKIKHPSEFTQIGAEIEVQVLEIDKENRR
                     LSLGHKQLEENPWDVFETIFTVGSIHEGTIIEVLDKGAVISLPYGVEGFATPKHLVKE
                     DGSQAQVDEKLSFKVIEFNKEAKRIILSHSRIFEDEQKGAKATSEKKASSKRGGKKEE
                     ESGMVTGPVEKTTLGDIEELAALKEKLSGK"
     gene            complement(3338..3580)
                     /locus_tag="ACZPB4_11375"
     CDS             complement(3338..3580)
                     /locus_tag="ACZPB4_11375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098849.1"
                     /translation="MGKNQLIHGNEFHLLKQAEIHKATGKLVESLNLAAGSTGGFDLY
                     KVVEAYFTDLEKRKEINDLLGISEPCETRVTEECFS"
     gene            3759..4406
                     /locus_tag="ACZPB4_11380"
     CDS             3759..4406
                     /locus_tag="ACZPB4_11380"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005775598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HIR1098850.1"
                     /translation="MKKLVIFDLDGTLLNTIADLAHSTNHALRQNGFPTHDVKEYNFF
                     VGNGINKLFERALPEGEKTAENILKVREEFLKHYDLHNTDRSVPYPGVPELLALLQER
                     GIKLAVASNKYQAATRKLIAHFFPSIQFTEVLGQREGVKAKPDPSIVNEIVERASISK
                     ENTLYVGDSDVDMQTAINSEVTSCGVTWGFRPRTELEKYAPDHIAEKAEDILKFI"
     gene            4752..5672
                     /locus_tag="ACZPB4_11385"
     CDS             4752..5672
                     /locus_tag="ACZPB4_11385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HIR1098851.1"
                     /translation="MSGNIKKIVEPNSGIDYSLEKDFKIFTLSKELPITTYPSYIRLG
                     IVIYCVKGNAKIDIYSNKHIITPKELIIILPGQLVALTDVSVDFQIRYFTITESFYSD
                     ILSGISRFSPHFFFYMRQHYYFKMEDVETLSFVDFFELLIRKAVDPENQYRRESVILL
                     LRILFLDIYNHYKVNSLDSTATIDVHKKELTHKFFQLVMSNYKVNRSVTFYANSLCIT
                     PKYLTMVVKEVSGKSAKDWITEYMILELKGLLTNSTLNIQEIVEKTQFSNQSSLGRFF
                     RRHTGLSPLQYRKKYLTTEQRTNFSKNNTI"
     gene            5669..5944
                     /locus_tag="ACZPB4_11390"
     CDS             5669..5944
                     /locus_tag="ACZPB4_11390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030527 - structural constituent of
                     chromatin [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HIR1098852.1"
                     /translation="MNKSQLIEELSKRVGNDKEEIRYILEELNNIILEKTRAGEKVCI
                     QGFGVYTPRLQTSRLARNPKSGETLMLIPRTIVHFKCAPNLLKEINK"
     gene            complement(6024..7118)
                     /locus_tag="ACZPB4_11395"
     CDS             complement(6024..7118)
                     /locus_tag="ACZPB4_11395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM barrel protein"
                     /protein_id="HIR1098853.1"
                     /translation="MNKDVNNGQSRREFLGRSVAALAAASFLPSAFSCTGKSVAAPAP
                     VDTAAEAGKVNSKFGGVQIGTITYSWRSMPGGLENIIKYCQEANISSIELMGGDLEAY
                     LGAPENPMMKFFRRQASQPAAKPDEKPAAPRRMGPPKFTPEQQAEIDKYKEEVKAWRL
                     GLDLSKVEGARKLLSDAGISVHIVKMQPSGMGSDEEVDYAFKVAKAMGAKAVTDEINL
                     ETAKRVAPFAEKHGMYMAFHNHMQYAEEGFSCDPILAISPSIMLNFDAGHFFGSTGIH
                     PNEMIKKYHDRIYSIHLKDKTGPTTGDQPNTNQVWGQGEMPLEDVLLLIKQEKWPIYC
                     DIELEYDIKPWSDSVKEVGTCVKYARQILM"
     gene            complement(7165..8646)
                     /locus_tag="ACZPB4_11400"
     CDS             complement(7165..8646)
                     /locus_tag="ACZPB4_11400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family protein"
                     /protein_id="HIR1098854.1"
                     /translation="MSNTMSDKNSVNFTRREFLGTVAAAAAFTIVPRSVLGGPGYTAP
                     SDMVNLAGIGVGSQGGGDIQNIATPDVPIKRRPFGGGGMLMQPYAGIQPPRRERRASD
                     NPVQMGDAEKQSFKHANIYALCDVDHDYSGHILAGYPKAKKYTDFREMIDKEKEIDAV
                     LIGTPDHTHAVIAAYAMKAGKHVFVEKPMAKTIYETRFLRDLAKQTGVVTQMGNQGHN
                     IEGTMQTVEWIQGGVIGDVKEVHLWTNRPMWRQGYFDRPAGVDIPSNLNYDVWLGPAP
                     DKPYNPEMLHFAWRGLWDYGTGAMGDMGAHTFDAPIWALNLGMPTKIQATSTPYNKDY
                     LPQSECVTYEFPARGNMPPVKVTWSDGGIKPARPAELEPNRQLREALYIGDKGLIMHG
                     THGAEPQLIPERPGFVAPEKTLKRPSNIYVDFIEAIKEGRKAANDFEVSAKLTEIMLL
                     TNIAVAAQRLDLTLEYDAENMRITNCPEANDYFHYEYRKGWSL"
     gene            complement(9081..11771)
                     /locus_tag="ACZPB4_11405"
     CDS             complement(9081..11771)
                     /locus_tag="ACZPB4_11405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LamG-like jellyroll fold domain-containing
                     protein"
                     /protein_id="HIR1098855.1"
                     /translation="MDDLIIKILYTMIAWFRYICLIVSLIITMPELLSAQRLVSQRQE
                     DVEAGLLYNESVYILSNYSCLSSNSPEKLSLDELLRKQIEGFYFYLKRDTETNVLLLR
                     KPDGTFTPFSESLEAIKTALDADSTKVMTLFLDFYVETELESSFKEIGLMEYVLEYDT
                     KNGWPSLKDMLSSGKRLVVFEVQKHLNSPSWLHNMRDFVEHTDADWGNQPEGVESFDE
                     RLKKNLSLFTGYKFLETSRGNSNDISALARQTPYLIESFKRAWIRDGRVPNFILVDKY
                     YAWLDVSLVTFRNFDIIYGAVTNNNELLNYVNWDGMSNYTTGKYCFPLEPGAELMLSP
                     ISPGYRIEPTTVYVSGTQRKAFASDFKARPLRIDEDIEIYLPFEGDEKDGSSNHNLTV
                     SRNVEFIQDPIRGQVASLENQARVDLPTASELHMRDHDFTVGVWLKIPKYLPEKEDYC
                     ILGAKNSTYQQALHLLIRNRKPYMGFFNNDLVGNTEIEPGKWYNVVWRYNKRNGEQAI
                     FVNGKLDAISFDRPAYLGSDSLYVGFVNFSQSSNFVGVLDNLCIWSRVLSDKEILGLS
                     NQLLDLHISNAITWLDILGIGLILMALVSIAYLGYRKVKEKPRQDEADAGTVAEEGIE
                     EGIEEPDRSSREMPEEIEEVPVLRNYIRLFGEFYVLDRDGNDITSLFTPKLKQLFILI
                     MLHSSRGGFGISSKDLTRMIWGNDNPSKSTKSLRSVSILKLRKILERIDTVEVLFNAN
                     RYILQLSEDVYCDYLACLDWLKDKRVRTQPDFEYFYDIISKGEVFKGESFDWMDDFKS
                     YICNSTVDVLSRFIDTYSIEDEADRVIQIADQILLNDPCNEEALLYKIKALIYQNNFK
                     LARYVYDRFCALYQEMYGEAFPSSFEQVVPSPLMSQQSPQ"
     gene            11843..12367
                     /locus_tag="ACZPB4_11410"
     CDS             11843..12367
                     /locus_tag="ACZPB4_11410"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIR1098856.1"
                     /translation="MDILEIMRKQDPLYPTFEQIYTASFPLFEQRTEEQQEQAFQSPN
                     YHLVVYLKDNLFIGFISYWDFSTYVYIEHFAIHENFRGQGYGGLLLEDFNKRLNKIIL
                     LEIDPITDEISSKRLKFYKKCGFFENRYNHFHPPYRNNYRGHALIILTTERQITEDEY
                     IQFGFDLRNIVMAN"
     gene            complement(12442..12924)
                     /locus_tag="ACZPB4_11415"
     CDS             complement(12442..12924)
                     /locus_tag="ACZPB4_11415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098857.1"
                     /translation="MEDIWNITALVVSVLSVLLSLYALRQATTKNTSDMYLFFISQYA
                     KEDMKLALRKLKDIKRGVYRLEQWESDMKNNLPKAFEYDEARRLVKYFYDTLAYMKLE
                     KLIEARFVRLICLKKGAWLYLDTVEAMEKFFDSGYDKKPYAVIRDVCENLRKEGCCPP
                     "
     gene            complement(12931..13626)
                     /locus_tag="ACZPB4_11420"
     CDS             complement(12931..13626)
                     /locus_tag="ACZPB4_11420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HIR1098858.1"
                     /translation="MEKCRKLVIVRHGNTFRAGETPTRVGARTDLPLVEEERARSAGR
                     YLREKGIVIDKVISAPLKRTLETANYILEEMNVDLPIIQDLRLKEIDYGPDENMVEDH
                     VIKRLGSLYLEKEGMERKDLTEDRIVERGLSVIAQWNEKAVVPLGWNVDVEKLISGWL
                     DLAASIPDGETWLLVSSNGVMRFSPYILGNYEDFCATHDIKVPTGGVCIFDCVGDHWR
                     CTDWGIKAYKLFK"
     gene            complement(13602..14270)
                     /locus_tag="ACZPB4_11425"
     CDS             complement(13602..14270)
                     /locus_tag="ACZPB4_11425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HIR1098859.1"
                     /translation="MESSIFRDLDGIVDSILSPYHTLEEVLPSGCDAGPVWMDFDCWV
                     DSQKVDMRTSESPLLLNICGIPASGKSYWAEEWLSENGPCLHIAFDAIMEALSGYQAD
                     YSLDRENAFLRWELPARFLGYRLLLLGLRNGWPILFEHSNALREHVDLYKKIKSLGYR
                     IHMVCIDATPEMVIKRLARRNRFFPEEQVKKRWDCLIDLLPEYQKIVDDFKLIQPWKN
                     VENL"
     gene            complement(14248..15069)
                     /locus_tag="ACZPB4_11430"
     CDS             complement(14248..15069)
                     /locus_tag="ACZPB4_11430"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008690 - 3-deoxy-manno-octulosonate
                     cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-manno-octulosonate cytidylyltransferase
                     family protein"
                     /protein_id="HIR1098860.1"
                     /translation="MEKVLIVIPARYDSSRLPGKPLVKIKGIEMIKRVSDIADFVCRK
                     NESCSYLVATDDERIVSFCESREIPVMMTSTNCKSGTERCYEAVRKQDTNPGLIINLQ
                     GDNPTCPPWILQDLIDTWRKEKADVLTASVLLGWSEYDQLLAMKKETPYSGTTVLVDR
                     LGYALAFSKQTIPAIRKEDQARDLLPKSPVRRHVGLYAYSGRALESYFSLPPSVYERS
                     YIEGLEQMRFLENGIKMRVVDVDYRGRETTSGVDSPEDVKRVEEILEKYGEFDLS"
     gene            complement(15081..16340)
                     /locus_tag="ACZPB4_11435"
     CDS             complement(15081..16340)
                     /locus_tag="ACZPB4_11435"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004308 - exo-alpha-sialidase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sialidase family protein"
                     /protein_id="HIR1098861.1"
                     /translation="MLISTQETLIYKSISPEDIYCYTPGITVTSTGRLVVTFDLGGKG
                     VKEIYASSQLYTERTRRLGIGKIFVSDDQGASWCFISDFNFWHARPFCIGEKIYIIGN
                     AGDLCIICSEDDGNTWSVPSFLSQGEKWHSSACNVLFANERVYLAMEQRFYNSEIEGW
                     NVAGLSPTLLSCSIHDDLLDASSWRRSDPFVFRDKVHFPEGVGIPFYESLTNKPLELA
                     PGRFNAPTGWLEAQVVQIKDKHHIWYDPEGKTFHMFLRAHTGGIGYACLLKVREDKNG
                     QMVTGFQETPSGQTLLFLPFPGGHLKFFIVYDEISRLYWMASNQSFDSMRTISSLPET
                     SRYGLPNNERHRLQLLFSKNCVDWCMAGMIACQGNELYSRNYPSLCIVGEDMHVVCRA
                     ADDHTKDPQYSDCITYYKIKRFRMLIY"
     gene            complement(16565..20020)
                     /locus_tag="ACZPB4_11440"
     CDS             complement(16565..20020)
                     /locus_tag="ACZPB4_11440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6383 domain-containing protein"
                     /protein_id="HIR1098862.1"
                     /translation="MNKKFSTLLAGAALVAAVSANAQNLADVKDGVALDINKSAQALP
                     TYDKDTKGGLYQLRDANDQILMMKEVNGEYSLVAMSANDKDFVLKNTLWCVTTQPYSQ
                     GQAVKFDFMNKGTGMMLDIAMGDDLKSADGKKGYWWKPIIGGEISGWAFSSVLNKLEK
                     NVPLYSHFSTDSVIGLLNDNGTIKVAKYALNDVKVDPTAATDVTDLSNLSTEAKNTFS
                     GFTLYQAEDIVLDADQLNKIFDLQDADAGVKLNFSPDVKGTSLKNPFNEKEFIAESTG
                     DNKYYDVNASSTATLTNGEWLYVTRKNDDNKDTYLKVDTAYTNETGAKFLAYGWTGPS
                     KTQEAIDRLGDLQDQHKFLFVYSPSKDELKIYVKKITWRGDDDKVKYWKEIYQKTDNQ
                     RNNWRVSLQDLIKDETRILTVDYSKQNTTIKLGYGGCEADQSKTSVKDGVYYIMNKKG
                     EYLASPIYENGVIRWTTVNADEQNVAHMPAYQWVVLKTNAKDQNNLSSVTATNREFDD
                     AKGTFSLYKNADTEYVYTKSNVELTQDGVSSKFTVAAKSDLRFVEVPAEAVSDSLLGY
                     KNLTNDELKVNKYTFNYWHPYATDKYIAKSSKDSTLTVNVGVSAFNVDTAKRSANSSV
                     YAVEKFGFKVEKEHQDRIKGLKQLYRTAYVVKLNGIGLAINKEDKFNVPTHNDYRTTG
                     ENKVVTPFFFKENNEIKETGKCYYAILSTEKDTKDVNDVHYSISDDNKAGVSDYDGSA
                     TLKSQVLKESRTSAFAIEPDETPLYRRFNSLELEGNEGDKADTLRFIEKYRKEYLQVE
                     NNKNFMNGDIDFLGIYTPDKTEDGLSFIVDTAWVNRGAGNIKPQYLISIDRNDFEGTS
                     GVACTYTHNHYDNEGNKVDAAHCSHATPAIPGFERGKYLINFHDFALKHDKANTSDAK
                     KDAAYMWKKYDRAGFVEAVRVADTLFILRDEFKNLKNEEITIEALNKAEEAAWAAAKK
                     AGVSKDNFVSYKYVLSGDNHKYVTWSMRFVNRNAAANEVEADRSFLFESMQADGLDIA
                     PTKAAWLKMQNGCLVLSDKDDSKFDETATGGDDALIFNVEQGDDIATDNETIDAVEGV
                     SITTDNGTVTIQGAAGKSVVISNILGKVVAETVLTSDNATIAVPAGIVAVAVDGEEAV
                     KVVVK"
     gene            21061..>21974
                     /locus_tag="ACZPB4_11445"
     CDS             21061..>21974
                     /locus_tag="ACZPB4_11445"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004536 - DNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HIR1098863.1"
                     /translation="MGKFINPFTDFGFKHIFGREMDKDILIEFLNDLLKGEHTIMDLR
                     IMNNERLPETEQGRKVIFDIHCETDKGERIIIEMQNREQPHFKDRALYYLSHSVVEQG
                     IKGTWDYKLAAVYGVFFLNFTLDEENKPNNNRNEGKFRRDIVLADRETGQVFNPKFRQ
                     IYIELPRFNKEEDECETDFERWIYVLKHMDTLDRMPFKARKAIFERLERIGSMANLTP
                     KQRAQYEAEWKMYNDYYNTLDFAVEKGMKKGMEKGLQEGLQEGLQKGKAEGKAEGRQE
                     EKHSIALNLKKLGVSIEQIAFATGLSIE"
BASE COUNT         6584 a         5290 c         4096 g         6004 t
ORIGIN      
        1 tcttgccgga ttccaaacgg gataaatcca ggacatcgtt caccagattc aatagcaact
       61 cggaactatg gttcacctcc ccggcaaacc ggatcttctc cacctcgcta tactcgctac
      121 tcgccaataa ttccgagaac ccgacaatgg cgttcaacgg cgtacgcacc tcatggctga
      181 tattggcgat aaaggcgctt tttttcttgt tcgccgcctc cgcctctttc gtcacgaccc
      241 gcagttgctt ctccgaagcg gtcaaggagt ctttctcctg aagcaactca tttctcaacc
      301 gcttagtatg catataaata cgccacaaca tatagagtag gcccatcaag accaatagaa
      361 gaccgataga tacgacaatc tgcttctgct tcaaagcttc ttgctccgat ttcagcttca
      421 actcccgatc ttgcttttcc aggtcattca agtcattcaa tacacggagt tgctcgattt
      481 gccggtcgaa ggcatccgtg ttgatcgtct ccgtcttatt gatgatctcc tcatagatag
      541 tgaccgcctc ttgcaattgg ccggatgatt gcaatatcgc tttcttcatc tccaacttat
      601 ccagatcacg attgatcttt aaagccagat tgacggcgga caacgcatgc ctataatctt
      661 tctccttcca ataataaaat gattttgtcc gcagatattg agcctccacc ctatccccaa
      721 aagaactatc caaataagcg gtcgcctgat ccaaatacgc ctgtgccttt cccgaattcc
      781 ctttcatggt atacagctcg caataatagc aactcatcaa gcaacgatga cgttttaccg
      841 gaaaaatctt tccctcccca ttatacttcc tttccaagga atccaataaa tgatcatact
      901 gtttcaagag cgcccccgac tcggacaaac gtcctaatag cagggtaata acgactcaag
      961 ccagccatcg catcgtatac gatcccgatg gaatccaaag gcatcgcgat atcgattatc
     1021 tctttcaacg ctggtacctc ctccggcaat tgccagtaca agccgattaa ttctttaaga
     1081 aggggtatct tatcctgagg tttttggata cgtgataaag attggcgtat gctatccgca
     1141 cgaaatttac tcacggcatt ctgcgcactt gtgcccaccg caaacaaaat ccacactatt
     1201 cctataaaag tattgacgct ggactttctt aaaaatcctc tactcattga tttatcgctt
     1261 acaattcgca aacttacaaa ataaatatca ataaaaatca acagttttcc gtaattacag
     1321 ccaacacgac ccaaatgaat gtttttaccc ctcaaaactc ttgtcaatca gaaaaaaagc
     1381 attacctttg ccccgatttt tgagagatga caacataaag tctaacttac taattaaaac
     1441 aaacttagta ttaacaatta aagaatggaa aatttaaaaa acatccagcc ggttgaagat
     1501 ttcaactggg acgctttcga gcaaggcgag acttacaccg aagtaagcaa ggacgatctt
     1561 gtaaaaacgt atgacgagac cctaaacacg gtaaaagaca aagaagtggt tatgggtacc
     1621 gttacttcta tgaacaaacg tgaggttgtt gtaaacatcg gtttcaaatc tgacggtgtt
     1681 gttcctatgt ccgagttccg ttataacccg gatttaaaga ttggtgacga ggtagaggtt
     1741 tacatcgaga gccaagaaga caaaaaagga caattgatcc tttcacacaa gaaagcacgc
     1801 gctacacgtt cttgggatcg tgttaacgag gctcttgaaa aagacgaaat tatcaaaggt
     1861 tacatcaaat gtcgtacgaa gggcggtatg atcgttgacg tattcggtat cgaagcgttc
     1921 ttgccgggtt ctcagatcga tgtgaagccg atccgcgact acgatgtatt tgtaggtaag
     1981 actatggaat tcaagattgt taagatcaat caagaattca agaatgttgt tgtatctcac
     2041 aaggctctta tcgaggctga gttggaacaa cagaagaaag atatcatctc caaattggag
     2101 aaaggacagg tattggaagg aactgtcaag aacatcactt cttacggtgt attcatcgac
     2161 ttgggtggcg tagacggttt gatccacatc acagaccttt cttggggacg tgtttctcat
     2221 ccggaagaaa tcgttcagct tgatcagaag atcaatgttg ttatcttgga cttcgacgac
     2281 gagaagaaac gtatcgctct tggcttgaag caattgactc cgcacccatg ggatgctttg
     2341 gatacgaact tgaaggttgg tgacaaggtt aagggtaaag ttgtcgttat ggctgactac
     2401 ggtgcgttca tcgagatcgc tccgggcgta gaaggtttga tccacgtttc agagatgtct
     2461 tggacacagc acttgcgttc cgctcaagac ttcatgaagg ttggcgacga gatcgaggcc
     2521 gtaatcttga ctttggaccg tgacgagcgt aagatgtctc ttggtatcaa gcaattgaag
     2581 gctgatcctt gggaaaacat cgaggagcgc ttcccggtag gttctcgtca tgcggctaag
     2641 gttcgtaact tcactaactt cggtgtattc gtagaaatcg aggaaggtgt tgacggcttg
     2701 atccacatct ctgacctgtc ttggacgaag aagatcaaac atccgtctga attcactcag
     2761 atcggcgctg agatcgaggt tcaagtattg gaaatcgata aggaaaaccg tcgcttaagc
     2821 ttaggccaca agcaattgga agagaatcct tgggatgtat tcgagacaat cttcacggtt
     2881 ggttctatcc acgaaggtac aatcatcgaa gtattggata agggtgccgt tatctctttg
     2941 ccttacggcg tagaaggttt cgctactccg aagcatcttg taaaagaaga tggttctcaa
     3001 gctcaagtag atgagaaact ttcattcaag gtaatcgagt tcaacaagga agctaaacgt
     3061 atcatccttt ctcacagccg catctttgaa gatgagcaaa aaggcgctaa ggcaacttct
     3121 gaaaagaagg catcctcaaa acgtggcggt aaaaaagaag aagaatctgg aatggtaacc
     3181 ggtccggttg aaaagactac attaggtgac atcgaggaat tggcagcttt gaaagaaaaa
     3241 ctttctggta agtaattgat ccttctttga gatataataa aaggagatat ctgattcagg
     3301 tatctccttt ttctatgtta ttcctactgc ggcttattta agaaaagcat tcttccgtga
     3361 cacgtgtctc acatggctcg gaaataccca acaaatcatt gatctccttt cttttctcta
     3421 aatccgtaaa ataagcctct acaactttat aaagatcaaa acctcccgta gaaccggctg
     3481 ccaagtttag tgactcgact aatttgcctg tagctttatg aatctcagct tgtttcagca
     3541 aatgaaattc attcccgtga attaattgat tctttcccat gatgttccaa ttttaggtta
     3601 tacaatatat tacaaaggat ttctattcct gtcctaaaga tacaaatatc ttatatatga
     3661 cctaatactt ttatctattt ttaaatcggt tcatctattt tatcagtcga aaggtaaagt
     3721 atgtctctac attccattaa ttttgccaga aaactaaaat gaaaaagtta gtaatattcg
     3781 atcttgacgg aacattatta aatacgatcg ccgatttagc ccatagcacg aaccatgcgt
     3841 tgcggcaaaa cggttttccg acgcacgacg taaaggagta taacttcttc gtaggaaacg
     3901 gcatcaacaa attattcgaa cgcgcgttac ccgaaggtga aaagacggca gagaatatac
     3961 taaaggtaag ggaagagttc ttgaagcatt acgatctgca taacacggat cgcagcgttc
     4021 cataccccgg tgtccctgag ttattagcct tgttgcagga aagagggata aaactggcgg
     4081 tcgcttctaa taaatatcaa gccgctaccc gtaagctcat cgcccatttc tttccttcca
     4141 tacaatttac ggaggttctc ggacagcgtg aaggagtaaa ggcgaagcca gatcccagta
     4201 ttgtcaatga gatcgtagaa cgagcgagca tatccaaaga gaacactctt tatgtcggtg
     4261 actcggacgt agacatgcaa accgccatca acagcgaagt gacctcctgt ggggtaacat
     4321 ggggctttcg ccctcgtacg gaattagaga aatacgcacc cgatcatata gcggaaaagg
     4381 cagaagatat actcaagttt atctaaaaga cgatctaagc ctgtcgtgcg aggcaatcct
     4441 tcccgttctt gtctcgcacg cttgtcctta accttaatta ctaatatttc ctaacacata
     4501 ttccatccag ctcgcacagc ccttagaata caagttatcc ctaacatcac ctcaaccgta
     4561 tttgcaaaaa agtattagac ctacaaacaa aaacatccaa tagcggttat ttttcaaggt
     4621 atcatttaag ccaaacttta aaaaacgcca aaacgagacc tatatttctg taatattata
     4681 ccaaacaacc actagataaa tatagtaaaa gacgaagtta taattttaca taagaaacat
     4741 agacaaaaag aatgtcggga aatattaaaa aaatagttga gccgaatagt ggtattgatt
     4801 attctttgga gaaggacttc aagatcttta cactttccaa agaactccct attaccactt
     4861 acccttctta tataagatta gggattgtca tctattgtgt aaaaggaaac gctaaaattg
     4921 atatctattc taacaagcac attataaccc ccaaagagct catcatcatc ttgccggggc
     4981 aattggtcgc attaacggac gttagcgtag atttccaaat cagatatttc acgatcacgg
     5041 aatcctttta ttctgatata ttaagcggta tcagtcgttt ctcgccacat ttctttttct
     5101 atatgaggca acattactat ttcaagatgg aagacgtgga aactctttcc tttgtagact
     5161 tctttgaatt acttataaga aaagccgtcg atccggaaaa ccagtatcga agagagtcgg
     5221 ttatactctt acttcgcata ttattccttg atatatataa ccattataaa gtcaattctt
     5281 tagacagtac ggcaacgata gatgtacaca agaaagaact gacccacaaa ttctttcaat
     5341 tggtcatgag taattacaaa gtgaacagaa gcgtgacgtt ctacgcgaac tctctatgca
     5401 tcacccctaa atacttgacc atggttgtta aggaggtaag cggcaaatcc gccaaagatt
     5461 ggattacgga atatatgatc ctagaattaa aaggattact caccaactcc accttgaata
     5521 tccaagagat tgttgagaag acgcagttct cgaaccaatc ctcgttggga cgcttctttc
     5581 ggaggcacac gggcttatcg cctttgcaat acaggaaaaa atatttaaca acagagcaaa
     5641 gaacaaactt ctcaaaaaat aatacgatat gaataaaagt cagctaatcg aggaattatc
     5701 gaaaagagtc ggtaatgaca aagaagaaat ccggtacata ttggaagaac tgaataacat
     5761 catcttagag aaaacgagag ccggagaaaa ggtatgtata cagggtttcg gtgtttatac
     5821 tccccgctta cagacaagca ggttggctag aaacccgaaa agcggagaga ctttaatgtt
     5881 gatccctaga accattgtcc attttaagtg cgcaccaaat ttgctgaaag agatcaataa
     5941 ataaaaaata aagggtcggc tccaccggga accgaccttt tcgtcatccc attaatgaca
     6001 taccaaagac aacattctat aatctacatc aatatctgtc gagcatattt cacgcaagtg
     6061 cctacctctt tcacggagtc agaccaaggc ttgatatcat attccagttc tatatcgcaa
     6121 tagataggcc atttctcttg tttgatcaac aagagcacgt cttccaacgg catctcccct
     6181 tgtccccata cttgattcgt attcggctgg tcccctgtcg taggccccgt cttatctttc
     6241 aagtggatac tatagatccg atcatgatat ttcttgatca tctcattcgg atggatacct
     6301 gtagagccaa agaagtggcc cgcatcaaaa ttcaacataa tagaaggaga gatcgctaag
     6361 atcggatcgc aactaaagcc ttcttcggca tattgcatat gattatggaa agccatatac
     6421 atcccatgct tctcggcaaa tggagcgact cttttcgccg tctccaaatt aatctcgtcc
     6481 gtcacggctt tagcgcccat ggccttggcc accttgaagg cataatcgac ctcttcgtcc
     6541 gatcccatgc cggaaggttg cattttcacg atatgcacag atatcccagc gtcgctcaac
     6601 aacttacggg caccttccac cttcgataga tccagcccga gacgccacgc tttcacctct
     6661 tccttatatt tatcgatctc agcctgctgc tccggagtaa acttcggggg acccatccga
     6721 cgaggagccg caggtttctc atccggtttc gccgcaggtt gagaagcttg ccgacggaag
     6781 aatttcatca tcggattctc cggagctcct aaataagctt ccagatcacc tcccatcaac
     6841 tcaatggaac tgatattcgc ttcttggcaa tacttgatga tattctccaa tccacccggc
     6901 atggaacgcc aactataagt gatcgtgccg atttgcacgc caccgaactt cgagttaacc
     6961 ttgcctgcct ccgccgccgt atcaaccgga gcgggagccg ccacactctt ccccgtacaa
     7021 gagaaagcac tcggaaggaa agacgcggcc gccaaagcag cgaccgatct tcctagaaac
     7081 tcacgtctgg actgaccatt gttcacatct ttattcataa ccattcaatt tataaattaa
     7141 tcttaaccct tagaagaaag tcccttacag gctccaacct ttacgatact catagtggaa
     7201 ataatcgttc gcttccggac aattcgtgat tctcatattc tctgcgtcat attccaacgt
     7261 aagatccaac cgttgcgcgg cgacagcgat attcgtcagc aacataatct ccgtcaattt
     7321 agcggatacc tcaaaatcat tagcggcttt gcgaccttcc tttatcgcct cgataaagtc
     7381 cacataaata ttactcggtc gctttaatgt cttctccgga gctacgaatc ccggtctttc
     7441 cggtatcagt tgcggctccg ctccatgggt accatgcatg atcaagcctt tatcgcctat
     7501 ataaagcgct tcccttaact ggcggttcgg ttccaactcc gccggacgag ccggttttat
     7561 acccccatca ctccaagtta cctttaccgg aggcatattc ccacgagccg ggaactcata
     7621 cgtcacgcat tccgattgtg gcagatagtc cttattgtaa ggggtggaag tagcttgtat
     7681 tttcgtgggc atacccaaat taagcgccca aatcggagcg tcgaaggtat gggctcccat
     7741 atcccccata gcgcctgtac cgtaatccca taacccacgc caagcgaaat gaagcatctc
     7801 cggattataa ggtttatcag gagccggtcc caaccacacg tcatagttaa gattagacgg
     7861 tatatccact cccgccggac gatcaaaata accttggcgc cacatcggac ggtttgtcca
     7921 caaatgaact tcctttacgt ctccgatcac gccaccttgg atccattcaa ccgtctgcat
     7981 agtcccttca atattatgcc cttggttacc catctgggta acaacaccgg tttgctttgc
     8041 cagatccctc aaaaagcgag tctcataaat cgtcttagcc atcggcttct ctacaaatac
     8101 atgcttacca gctttcatcg cataagcggc aataaccgca tgggtgtggt ccggagtacc
     8161 gatcaatacc gcatcgatct ctttctcctt gtcgatcatt tcccggaaat cggtatactt
     8221 cttcgctttc gggtatcccg ctaagatatg tccggagtaa tcgtggtcta catcacatag
     8281 cgcataaata ttcgcatgct taaacgattg tttctccgca tctcccattt gcacaggatt
     8341 atccgacgct cttcgttccc gtctgggtgg ctggatgccc gcataaggtt gcatcagcat
     8401 accgcctcca ccaaaaggtc tccttttaat tggtacatcc ggagtagcga tattctgtat
     8461 atcgccacca ccttggctac ccacaccgat accggccaaa ttgaccatat cgctaggtgc
     8521 cgtatagccc ggtccaccca aaacggaacg aggtacgatt gtaaacgccg ccgctgcagc
     8581 tactgtacct aagaactccc tacgtgtgaa gttcaccgaa ttcttgtcag acatagtgtt
     8641 actcatagta ttaaatttaa agtcgaaaaa aaatatatat agtaaaacac aacttcgctt
     8701 cctcgtgcga aacaacgaga gcgaatatag ggaggagcag taaaccatga gttaacgaac
     8761 gctaaacaag gcattaacct agggctaatt taaggcaaat ttcatatcct cacaaagcat
     8821 aattcacgca ataacagcga cataaataaa tcaagaaata tttataaaaa tcttcgataa
     8881 gtcagaggca tagcacctgc ctctctattc gaaaggatcg ctatcagtgg ggcgcataca
     8941 tttgccactg taatggcaga ggagtgccac acggatggca caggcatgcc ataacggtgg
     9001 cacggtcttg ccacaacgat ggcacaggtg tgacaatagc aatggcacag tcctgccaat
     9061 gagcaggcac actataatac ttactgggga gattgctgac tcatcagcgg agacggtacg
     9121 acctgctcaa aagaagaggg gaaagcctcg ccatacatct cttggtataa agcgcaaaag
     9181 cggtcgtaca cataacgggc caatttaaag ttgttctggt aaatcaaggc tttgatctta
     9241 tagagcaaag cctcctcgtt gcaaggatcg ttcagaagga tctggtctgc tatctggatc
     9301 acccgatccg cctcatcctc gatcgagtaa gtgtcgataa agcgagacaa gacatccacc
     9361 gtactattac agatataact tttaaaatca tccatccaat caaacgattc ccctttgaac
     9421 acttctcctt tgctgataat atcatagaaa tattcaaagt ccggctgagt ccgtacccgt
     9481 ttatctttca gccaatccaa acaagccaaa taatcgcaat agacatcttc cgaaagctgg
     9541 agaatatatc gattcgcgtt aaatagaacc tcgaccgtat cgatacgttc caatatcttc
     9601 cggagtttca atatagatac gcttcgaagg ctcttcgtac ttttcgaggg gttgtcattc
     9661 ccccaaatca tccgtgtcaa gtccttgctc gatatcccga aacctccacg ggaagagtga
     9721 agcataatca agataaacag ctgttttaat tttggggtaa atagagaggt tatatcattt
     9781 ccatcccggt ccaacacata gaactctcca aacaatcgga tataattgcg cagaaccgga
     9841 acctcctcaa tctcctccgg catctctcgc gaagaacgat ccggctcctc gattccttcc
     9901 tcgattccct cctccgcgac cgttcccgca tcagcctcat cctgccttgg cttttctttc
     9961 accttccgat agcctagata agctatcgag accagagcca tcaaaatcaa cccaattcca
    10021 aggatatcca accaagtaat cgcattcgat atatgtaaat ctaataactg gttgctcaat
    10081 cccaatatct ccttatcgct caacacacga gaccaaatac aaagattatc cagcacaccc
    10141 acgaagttcg aggactggct gaaattcacg aaaccgacat ataagctatc actacccaga
    10201 taagccggac gatcaaaaga gatcgcgtcc agttttccat tcacgaatat agcctgctcc
    10261 ccattccttt tattataccg ccatacgaca ttgtaccatt tgcccggctc gatctccgtg
    10321 ttaccaacca gatcgttgtt aaagaatccc atatacggtt tccggttccg tatcaacaga
    10381 tgcaacgctt gttgataagt actgttctta gctcccagaa tacaataatc ctccttctcc
    10441 ggcaggtact taggtatttt caaccaaacg ccgacagtga aatcatgatc ccgcatatga
    10501 agttccgaag cggtcggtaa atccacacgg gcctgattct ccaaggaagc gacctgtccc
    10561 cgtatagggt cctgaataaa ctcgacattc ctagataccg tgagattatg attggacgaa
    10621 ccatctttct catcgccctc aaacggtaaa taaatctcta tatcctcgtc aatccgcaaa
    10681 ggtctagcct taaaatcgct agcgaaagcc ttcctttggg taccggagac ataaaccgta
    10741 gtcggctcta tcctatagcc cggagagatc ggggagagca tcaactcggc cccgggctct
    10801 agcggaaagc aatatttacc cgtcgtataa ttagacatcc catcccaatt cacgtagtta
    10861 agcagctcat tgttattcgt aactgcgccg tagatgatat cgaaattccg aaaagtaacc
    10921 aacgagacat ccaaccacgc gtaatactta tctaccaaga taaaattggg aacccttcca
    10981 tcccggatcc acgctctttt aaacgattca attaaatagg gcgtctgccg ggctaaagct
    11041 gagatatcat tgctattccc ccgggaagtc tccaagaact tatatccggt aaataaagac
    11101 aaattctttt tcagccgctc atcaaaactc tcaacccctt ccggttggtt gccccaatca
    11161 gcgtccgtat gctccacgaa atccctcata ttatgcaacc atgaaggact gttcaaatgt
    11221 ttctgaacct cgaaaacgac cagtcgcttt ccggaactca acatatcctt cagggatggc
    11281 catccgtttt tcgtatcata ctcaagtaca tactccatca agcctatttc cttaaaagag
    11341 gattccaact ccgtctctac atagaaatca aggaaaagcg tcataacctt agtggagtcc
    11401 gcatccaagg ccgtcttaat ggcttccaat gactcactaa aaggggtaaa cgtaccatca
    11461 ggtttcctta gtaacaatac atttgtctcc gtatcccgct tcaaatagaa ataaaagcct
    11521 tcgatctgct tccgcaacaa ctcgtccaaa gaaagttttt ccggggaatt ggaggataga
    11581 caagaataat tagataggat gtagacgctc tcgttatata aaagaccggc ctctacatcc
    11641 tcttgacgtt gagaaaccag acgttgtgcc gaaagtaatt ccggcatagt gattataagg
    11701 ctaacaatta aacatatata acgaaaccac gctatcatcg tatacaatat cttaattata
    11761 agatcatcca aaaataaagc tttaatatga catgacaatg tttttagatt attatcttcg
    11821 catcaaaata aagcgaagtc atatggacat actagaaata atgcgaaagc aagatcctct
    11881 ctatcctacc tttgagcaaa tatatacggc aagtttccct ctatttgagc aacgaacaga
    11941 agaacaacaa gaacaggcct tccaatctcc caactatcat ctagtggttt atctgaaaga
    12001 taacctcttt atcggcttta tctcatactg ggattttagc acctatgtat atatcgaaca
    12061 tttcgccatt catgagaact ttaggggaca aggatacggc ggtttattgc tggaggattt
    12121 taataaacgc ctgaataaga tcatcttatt agagatcgat cctattacgg atgaaatttc
    12181 ctccaagcga ttaaagttct ataaaaaatg cggcttcttc gaaaaccgtt acaaccattt
    12241 ccatccccct tacagaaaca actatcgagg gcatgcgtta atcatcctga caacagagag
    12301 gcaaatcact gaggatgagt atattcaatt cggtttcgac ttgcggaata ttgtcatggc
    12361 aaattaagaa ataaatataa aagccccgat cgtttcttcg atcaaggctt tattaaatca
    12421 ccaaaagccg aaaataatga actaaggagg acaacaccct tcctttcgta aattttcgca
    12481 tacatcccga ataaccgcat atggcttttt atcatagcca ctgtcaaaaa atttttccat
    12541 ggcttcgact gtgtccagat aaagccatgc ccctttcttc aagcaaatca atcttacaaa
    12601 acgagcctct attagtttct ccaacttcat ataggctaaa gtatcataaa aatatttcac
    12661 caaacgtctc gcctcgtcat actcaaaggc tttcggcaaa ttatttttca tatcactctc
    12721 ccattgttcc aaccgatata ccccccgctt tatatctttc aatttacgta aagccaattt
    12781 catgtcctcc ttcgcatatt gcgagataaa gaacagatac atatccgagg tatttttagt
    12841 ggtagcctgt cttaaagcat aaagagacaa aagcacactt aatacactaa ctaccaaagc
    12901 tgttatattc catatatctt ccatgattta tcatttaaaa agtttataag cctttattcc
    12961 ccaatccgta cacctccaat gatcacccac acaatcgaat atacaaaccc cacctgtcgg
    13021 aaccttaata tcatgagtcg cacagaaatc ctcataattc cccagaatat agggggagaa
    13081 acgcatcact ccattggaag atactagcag ccaagtctca ccatcaggta tactagccgc
    13141 caaatccagc caaccgctta tcagtttctc tacatctacg ttccatccta acggtaccac
    13201 ggccttctca ttccattggg cgatcacgga aagtcccctc tccacgatcc gatcttctgt
    13261 taggtctttc cgctccattc cctccttttc taaatagaga gatcccaaac gttttattac
    13321 atgatcttct accatattct catccggccc ataatcaatc tctttaagac gtaagtcttg
    13381 aatgataggc aaatccacat tcatttcctc caagatatag ttagcggtct ccaatgtacg
    13441 ttttaagggg gccgaaatca ccttgtcgat cacaatcccc ttttcacgta aataacgtcc
    13501 cgcagatcta gctcgttcct cctctaccag aggcaaatca gttctagctc caacccgagt
    13561 cggagtctct cccgcacgaa acgtattacc atgccgtacg atcacaagtt ttctacattt
    13621 ttccatggtt gtattaattt aaagtcatct actatttttt gatattcagg taacaaatct
    13681 atcaagcaat cccaacgttt ttttacttgc tcctccggga aaaaacgatt cctccgagcc
    13741 aatcttttga taaccatttc tggtgtcgca tcgatgcaca ccatatgaat ccgatatcca
    13801 agactcttta tcttcttata caaatccaca tgttctctca atgcattact atgttcaaat
    13861 aaaataggcc acccattcct caatcccaac aaaagaagac ggtaacctaa aaaacgagca
    13921 ggaagttccc aacgtaagaa cgcattctcc ctatctagcg agtaatccgc ttgatacccg
    13981 gataatgcct ccataatagc gtcgaaagcg atatgcaaac aaggtccatt ctctgatagc
    14041 cattcctccg cccaatacga tttaccggat gcgggtatac cacatatatt caagagtaag
    14101 ggtgattccg atgtccgcat atccaccttt tggctgtcta cccaacagtc aaaatccatc
    14161 cataccggac cagcatcaca gccagaaggt agaacctcct ccaaagtatg gtagggagat
    14221 aaaatagaat ctacgattcc atctaagtca cgaaagatcg aactctccat acttctcaag
    14281 tatttcctca acccgtttaa catcttccgg ggaatcaacc ccgcttgttg tctcacgtcc
    14341 ccgataatcg acgtctacga ccctcatttt gatgccattc tctaagaagc gcatctgttc
    14401 caatccttct atataagagc gttcatacac agacggaggt aatgagaaat aagactcgag
    14461 ggctcgaccg ctatacgcat ataaacccac atgccgcctg acagggcttt taggcaaaag
    14521 atccctagcc tgatcttcct tacggatagc gggtatggtt tgtttcgaga aagctaaggc
    14581 atatcccagc cgatccacca ataccgtcgt gccggaataa ggggtttcct ttttcatcgc
    14641 cagtaattga tcgtattcgc tccatcccaa caagaccgag gcggtaagga catccgcctt
    14701 ctcctttctc catgtatcga tcagatcttg caagatccaa ggaggacacg tgggattatc
    14761 gccttgcaga tttattatca gtccgggatt ggtgtcctgt ttccttaccg cctcatagca
    14821 acgttccgta ccacttttac aattcgtgga agtcatcatc accggaatct cccgggattc
    14881 gcaaaacgag acgatgcgct catcatccgt agctaccaaa taagaacaag actcattttt
    14941 gcgacataca aaatccgcta tatccgagac ccgttttatc atctctatac ctttaatctt
    15001 aaccaaaggc ttacccggca accggcttga atcataccga gccggtatta caatcagtac
    15061 tttttccata atcacttcat ttaatagatt aacattctaa accgtttaat tttataatat
    15121 gtaatacaat cagagtattg agggtccttt gtatgatcat ccgccgcacg gcaaaccacg
    15181 tgcatatcct cacctacgat acataacgaa ggataatttc ttgaatataa ttcattccct
    15241 tggcaagcga tcatcccagc catacaccag tccacacaat tcttcgagaa taataattgt
    15301 aaacgatgcc tctcattatt cgggagtcca taccgggaag tctcaggtaa tgagcttatc
    15361 gtccgcatag aatcgaaaga ttgattggat gccatccaat acaaccggga tatttcatca
    15421 tacactataa agaatttcaa atggccaccg ggaaagggca agaaaagcaa ggtctgtccg
    15481 gaaggagtct cttgaaagcc ggttaccatc tggccgttct tatcttccct cacttttaat
    15541 aaacaagcgt atccaatccc tccggtatgc gcacgaagaa acatatggaa cgttttcccc
    15601 tccggatcat accaaatatg atgtttatcc tttatttgaa ccacttgagc ctccagccat
    15661 ccagtgggcg cattaaaacg accgggagcc aattccagcg gcttattggt caatgactcg
    15721 taaaaaggaa tgccaacccc ttccgggaaa tgtaccttat ccctgaaaac aaaaggatcg
    15781 gaacgtcgcc aagaagacgc atccagtaaa tcatcgtgaa tagagcaaga tagcaaggta
    15841 gggctcaaac ccgccacatt ccagccttct atctccgagt tataaaaacg ctgttccatc
    15901 gccaagtaaa cccgctcgtt agcgaaaaga acattacagg cagaagaatg ccatttctca
    15961 ccttgggaga gaaacgaggg aacgctccac gtattcccat catcttccga gcatataata
    16021 cataaatcgc ctgcgtttcc tatgatatat atcttttccc ctatacaaaa agggcgggca
    16081 tgccaaaaat taaaatccga gataaaacac caactagcgc cttggtcgtc cgatacaaaa
    16141 atcttaccga tacctaaccg tcttgtcctt tccgtgtaca gctgcgaaga agcatagatt
    16201 tcttttaccc ccttgccgcc caagtcgaaa gtcacgacca agcgtcccgt cgaagtcacg
    16261 gtgattccgg gagtataaca ataaatgtct tccggactaa ttgatttata gatcaatgtt
    16321 tcttgagtag atataagcat agcacgagat ttaagagtac aaaaaaaggt cacgacattt
    16381 cttcacagaa gttctcgtga cctgagcttt taatttatta ctttagtatt aatacccccg
    16441 catgttctac catcgcggtg tacttgaaga atctatctcc gcacgggaat ttcagaatta
    16501 taaatatctt cttaaaggta gagatggggg attctcccat ctcttgacct atctatttgt
    16561 ttaattattt aacaaccact ttaacagctt cctcaccatc aacagctaca gctacgatac
    16621 cggcaggtac ggcaattgtt gcgttatcag atgtaagaac tgtctcagcg actaccttac
    16681 ctaagatgtt agagataact actgatttac cagcagcgcc ttggatagtt acagtaccat
    16741 tatcagttgt gatggaaaca ccttctacag catcgattgt ctcgttatct gtagcgatat
    16801 cgtcaccttg ctctacgttg aagattaaag cgtcatcacc accggtagca gtttcgtcaa
    16861 acttagaatc atctttatca gacaatacca agcaaccatt ctgcattttc aaccaagcag
    16921 cttttgtagg agcgatgtca agaccgtctg cctgcattga ttcgaacaag aatgatctat
    16981 cagcctcaac ctcattagcg gcagcatttc tgttaacgaa acgcattgac caagtcacat
    17041 acttgtggtt gtcaccagat aaaacatatt tgtaagatac gaagttatcc ttgcttacac
    17101 cagccttctt agcggcagcc caagctgctt cctcagcctt atttaaagcc tcaatcgtga
    17161 tctcctcatt cttcaagttc ttgaattcgt ctctcaagat gaacaatgta tcagctacac
    17221 gaacagcctc tacgaaaccg gcacgatcat atttcttcca catataagcg gcgtctttct
    17281 tcgcatcgga agtattagcc ttatcatgtt tcaaagcgaa atcatggaag ttgatcaaat
    17341 acttacctct ctcgaaaccg gggatagccg gagtagcatg tgaacagtgc gctgcgtcta
    17401 ccttgttacc ttcattgtca tagtgattat gagtatatgt acaagcaaca cccgatgtac
    17461 cctcgaagtc gttacgatcg attgagatca aatactgagg tttgatatta ccagcgccac
    17521 gatttaccca tgccgtatca acgatgaatg acaagccatc ttccgtctta tccggagtgt
    17581 agatacctaa gaaatcgata tcaccattca tgaaattctt gttgttctca acttgcaagt
    17641 actctttacg atatttctcg atgaaacgta atgtatcagc cttgtcacct tcattacctt
    17701 caagctcaag agaattgaaa cgacggtaca gtggagtctc atccggttcg atagcgaatg
    17761 cggatgttct ggattctttc aatacttgag atttcaatgt agcagagcca tcatagtcag
    17821 atacaccagc cttgttgtca tctgaaattg aataatgtac atcgtttaca tctttagtgt
    17881 ctttttcagt agacaagatc gcataataac acttacccgt ttctttgatc tcattattct
    17941 ccttgaagaa gaacggagta accaccttat tctcgcctgt agtccgataa tcgttatgag
    18001 taggtacatt gaacttatcc tctttattga tagctaagcc aataccattt aatttcacta
    18061 cataagccgt tctataaagt tgtttcaagc ctttgatacg atcttgatgt tctttctcta
    18121 ccttgaaacc aaacttctct accgcatata cagagctgtt tgcacttctc ttagcagtat
    18181 ctacattaaa ggcagataca ccaacattaa ctgtcaaagt agagtcttta gaagacttag
    18241 cgatgtattt atccgtcgca tacggatgcc agtaattaaa tgtatattta ttaaccttca
    18301 actcatcgtt cgttaagttc ttataaccta acaaagaatc agatacagcc tcggccggaa
    18361 cctctacaaa acgtaagtca ctcttcgctg ctactgtaaa tttagaagaa acaccatctt
    18421 gtgttaattc tacattgctt tttgtatata catattccgt atcagcattc ttatacaaac
    18481 taaatgttcc tttcgcatca tcaaactcac ggttagtagc tgttactgaa gacagattat
    18541 tctgatcttt agcgtttgtc ttcaaaacaa cccattgata ggctggcata tgagctacat
    18601 tttgctcatc agcattcacg gtagtccaac gaatcacgcc attctcatag atcggagaag
    18661 ctaagtactc acccttcttg ttcatgatgt agtaaacacc atccttaaca gaggtctttg
    18721 attgatcagc ctcgcaacca ccataaccta atttgatggt tgtattctgt ttggaataat
    18781 caacggtcaa gatacgagtc tcatccttga tcaaatcttg caaagacaca cgccagttat
    18841 ttctttggtt gtctgtcttt tgataaatct ctttccaata ttttacctta tcatcatcac
    18901 ctctccaagt gatctttttt acatagatct tcaattcatc tttgctagga gaataaacaa
    18961 ataagaactt atgttgatct tgtaaatccc ctaagcgatc aatagcctct tgtgttttgc
    19021 taggaccagt ccagccataa gccaagaact tggcaccggt ctcatttgta taagctgtat
    19081 cgaccttcaa ataagtgtcc ttattatcat cgttcttacg tgtcacataa agccattcgc
    19141 catttgtcaa agtcgcagta ctgctagcat tcacatcgta atacttgtta tcacctgtag
    19201 attcagcgat aaattccttc tcgttgaacg gattctttaa gctggtaccc ttaacatccg
    19261 gagagaaatt caatttaaca cccgcatcag catcctgcaa atcgaaaatc ttattcaatt
    19321 gatccgcatc taatacgata tcttctgctt gatacaaagt aaagccagag aacgtattct
    19381 tcgcttcagt tgaaaggttt gaaagatctg taacgtctgt agcagctgta ggatctacct
    19441 ttacatcatt caaggcatat ttagcgacct tgatagttcc gttatcgttc aacaaaccaa
    19501 taacagagtc tgtgctaaag tgagaataca aaggaacatt cttctccaac ttattcaata
    19561 cagaagaaaa ggcccaacca gagatctcac caccgattat aggcttccac caatagccct
    19621 tcttaccatc cgcacttttc agatcatcac ccatagcgat atccaacatc atgccagtac
    19681 ccttgttcat gaaatcgaat tttaccgctt gaccttgact atacggctga gtagtcacac
    19741 accataacgt atttttcaaa acaaaatcct tatcattggc actcattgcg accaatgaat
    19801 attcgccatt cacttccttc atcatcaaga tctgatcatt cgcatctctc aattgataaa
    19861 ggccgccttt ggtatctttg tcatacgtag gcaaagcttg tgcacttttg ttaatgtcaa
    19921 gagccactcc gtccttaaca tcagcaagat tctgcgcatt agcagatacc gcagcaacaa
    19981 gcgcagcacc tgccaaaaga gtagaaaact ttttgttcat aataaataaa ttaatattaa
    20041 tactagtgtt tattaagata atcaacctgt tagactaatt gaaaatcgtc gtttgctatt
    20101 aaaaacgact agtctaaacg atcgtctaaa tcttgcgttt ttgagtgtcg aaacgggagg
    20161 ttcgttgaag gaatcgcttg tttcgtgaag gataacctat cctattgata agaaagagaa
    20221 taagcgataa aaaaatcgtc tggaagggtt gcaagtatcg aagaaatgcg tacctttgca
    20281 aatgactaaa agaatcgatc gtttaaacta gtcgtttcta tactagaaaa gcatttatta
    20341 atcatacaaa cttttctatc atatactaaa tgtacatgcg tacattgtat atctatatca
    20401 aagtaacact ttgacatttt gtattcttaa ctcccagaga atcgactttt tcaggctccc
    20461 ccgataaata gtgggaataa tctcgcaatg tacttttatc tacactttaa tttgtttatc
    20521 acacgtttca catcggtcaa cttgctttat gtcagtgata tgttgtgaag gatgtgaaag
    20581 ggagcgcaga gatgcctacg aagagttgtt accgttgagc ctttctattt aatacaaaca
    20641 ttatcggcag tagcttgctc tatctgccca tgaaatcgtt tcacggttgt gatacaatct
    20701 tttcacctat gcgaaacgat tgtatcacgt aggtgaaaag atctcttcac gaatgtgaaa
    20761 tgatcagatc atgtagtgcc tggccatact atcccttggt ggaatataca ttcaggaaaa
    20821 ttatccccac gatttatcgg ctgatccggt atttgaagta gttacattat gcctctcaaa
    20881 aaacacgtac gagtttttcg aaaaacatgt acgtgtttcc gaaaaaactc gtacgtgttt
    20941 tcttaaaagc taaaacgatg cctatcctat taaaaaagta gtatctttac aaccggaaga
    21001 caggatgccc cgtctcatta tactattatt cattattaat cactgaaatc tataaacact
    21061 atgggaaaat ttatcaatcc cttcaccgat ttcggcttca agcacatatt cggcagggaa
    21121 atggacaagg acatactaat cgagttcctg aacgacctcc tcaaagggga gcatacgatc
    21181 atggacttga ggatcatgaa caatgagcga ttgcccgaga cagagcaagg aaggaaagtc
    21241 atctttgaca ttcattgcga gaccgacaag ggcgaacgga tcataatcga gatgcagaac
    21301 agggaacagc cccacttcaa ggacagggcc ttgtattacc tctcgcactc ggtggtggaa
    21361 caggggataa agggaacatg ggactataag ctagcggccg tgtacggtgt tttcttcttg
    21421 aacttcacgc tggacgagga gaacaagcca aacaataaca ggaacgaagg aaagttccga
    21481 agggacatcg tgctagcgga ccgagagacc ggacaggtat tcaaccccaa gttccgccag
    21541 atctatattg agcttccccg attcaacaaa gaggaggatg aatgcgagac agattttgaa
    21601 cgttggattt atgtattgaa acatatggac acattagaca gaatgccatt caaggcacgc
    21661 aaggccatat tcgagcggtt ggaacgcatc ggatccatgg cgaacctcac ccccaaacaa
    21721 cgggcgcagt acgaggcgga gtggaagatg tataatgatt attacaacac cttggacttc
    21781 gccgttgaga aaggcatgaa aaaagggatg gaaaaaggat tgcaggaagg tttgcaagaa
    21841 ggtttgcaaa aaggaaaagc agaaggaaaa gcagaaggac gacaggaaga gaaacactcc
    21901 atagcactta atcttaagaa attaggagtt agtatagagc aaatcgcctt tgccaccggc
    21961 ctctccatag aaga
//
LOCUS       DBMDTB010000069        21716 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_815_length_21716_cov_11.630858, whole genome shotgun sequence.
ACCESSION   DBMDTB010000069 DBMDTB010000000
VERSION     DBMDTB010000069.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 21716)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 21716)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21716
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_815_length_21716_cov_11.630858"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..1946)
                     /locus_tag="ACZPB4_11450"
     CDS             complement(<1..1946)
                     /locus_tag="ACZPB4_11450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PEP/pyruvate-binding domain-containing protein"
                     /protein_id="HIR1098864.1"
                     /translation="MSGIPNLKDLVFRDTPFANLMNKRIYNVLLIATKYDSFMLEDDG
                     RVDEQIFNEYTSLSLRYPPRFTQVTTEEEALNELKNRNFELIICMPNMDNRDIFAAAS
                     EIKVHYPNIPIVVLTPFSKEVSKRIANEDLSAIDYVFSWLGNSELLLAIIKLIEDKMN
                     APDDTASVGVQIILLVEDSIRFYSSALPHLYKFVLEQSQMFAKEALNDHQRTLRMRGR
                     PKIKLARNYEEAVRIFDQYRDNMLGIISDMSFMHNGVKDPYAGYKFGQYVRKTGLIIP
                     FVLESSEASNHVYAKELNASFIDKNSKSYPQDLKKKIMQRFGFGDFVILNPHTKEEIM
                     RIKDLKDLQKKVFQIPDDSLVYHLSRNHFSRFFYSRAMFPPAEVLKHVDVSDYKDMDE
                     ARKLIFDLIVQYRRMKNTGVVAVYQKDRFDEYSNFARIGDGSLGGKGRGLAFIGAMVK
                     RYPKLESDNFAVNIPKTVVICTDIFDEFMETNELYPVALGDADDETILRYFLRASLPS
                     RLIEDLMAFFDVVKSPIAVRSSSLLEDSHYQPFAGIYSTYMVPKIEEKYDMLRTVSDA
                     IKAVYASVFYKDSKAYMTATSNLIDQEKMAIVLQEVVGSRYNDHFYPTMSGVARSLNF
                     YPIGNEKAEDGIANIALGLGKYIV"
     gene            2142..3476
                     /gene="gdhA"
                     /locus_tag="ACZPB4_11455"
     CDS             2142..3476
                     /gene="gdhA"
                     /locus_tag="ACZPB4_11455"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007217307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016639 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HIR1098865.1"
                     /translation="MKTEVILSALEAKHPGEKEYLQAVKEVLLSIEEVYNQHPEFEKA
                     KIIERLVEPERIFTFRVPWVDDKGEIQVNLGYRVQFNNAIGPYKGGIRFHPSVNLSIL
                     KFLGFEQTFKNALTTLPMGGGKGGSDFAPRGKSDAEIMRFCQAFILELWRNLGPDRDV
                     PAGDIGVGGREVGYMYGMYKKLARENTGTFTGKGMEFGGSILRPEATGFGALYFVHQM
                     LETHGIDIKDKTVAISGFGNVAWGAATKATELGAKVVTISGPDGYIYDPAGISGEKID
                     YMLELRNSGNDIVAPYADEFPGSTFYPGKKPWEQKVDIALPCATQNELNEADARKLIE
                     NKTLCVAEVSNMGCTAEAVDLFIEHKQLFAPGKAVNAGGVATSGLEMTQNAMHISWTA
                     AEVDAKLHQIMSAIHEQCVAHGKDGEYINYVKGANIAGFMKVAKAMMAQGIV"
     gene            complement(3575..4132)
                     /gene="ruvC"
                     /locus_tag="ACZPB4_11460"
     CDS             complement(3575..4132)
                     /gene="ruvC"
                     /locus_tag="ACZPB4_11460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008821 - crossover junction DNA
                     endonuclease activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="crossover junction endodeoxyribonuclease RuvC"
                     /protein_id="HIR1098866.1"
                     /translation="MIKDRIILGIDPGTIVMGYGILKIEGNKPKLEAMGILQLNKYED
                     HYLRLRKIFERVLALIDQYHPDELAIEAPFFGKNVQSMLKLGRAQGVAMAAALERDVP
                     IFEYAPLKIKLSITGNGNAAKEQVAGMLQRYLKIPDESMLPQLDATDGLAAAVCHYFQ
                     TNNPISEKKYTGWKDFIAKNPGKVR"
     gene            complement(4129..4443)
                     /locus_tag="ACZPB4_11465"
     CDS             complement(4129..4443)
                     /locus_tag="ACZPB4_11465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4286 family protein"
                     /protein_id="HIR1098867.1"
                     /translation="MIIYNTTFHIHKDIVDECLEYLKNSYIPKASESGILYSPYLRRI
                     LDSRNEEGESFSVQFHTRDIDSLNEWVRKEGGALQQDLIGRYKEKIAGFSTLLEDIEL
                     PK"
     gene            4530..4606
                     /locus_tag="ACZPB4_11470"
     tRNA            4530..4606
                     /locus_tag="ACZPB4_11470"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4564..4566,aa:Ala,seq:ggc)
     gene            complement(4845..4917)
                     /locus_tag="ACZPB4_11475"
     tRNA            complement(4845..4917)
                     /locus_tag="ACZPB4_11475"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(4882..4884),aa:Thr,seq:cgt)
     gene            complement(4957..5418)
                     /locus_tag="ACZPB4_11480"
     CDS             complement(4957..5418)
                     /locus_tag="ACZPB4_11480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098868.1"
                     /translation="MNANMAKVQSLIENAFTSAVEKLAKDESGNFISDLYVQADAESG
                     ELQIYDDEEHLIEKIVIFDWVNSNEEENAFNKRVAASVKAVLTILSTKNIFDVPRFMK
                     PLSVSLTDEDFVVIEELLFIDDDMLRLDDPLLKDLDADLDDFLANLLADVK"
     gene            complement(5481..6515)
                     /locus_tag="ACZPB4_11485"
     CDS             complement(5481..6515)
                     /locus_tag="ACZPB4_11485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6340 family protein"
                     /protein_id="HIR1098869.1"
                     /translation="MRSILFIGIAGLLSACSTINYVGIETYNPAEVTFPENVAKVLIV
                     NNAVPQPEDAGYEYTLQGEKQDTCKAKADSALFDACRTLGEAIVEASYFNDVLLYHDG
                     VRKDNQAFLDTKLTQGQVASLCDETGADAVISIDRLLFDMKKSVGTLGEGYVMGMIDV
                     QMAGVIRSYVPDREAPLATVHMKDSIYWAESADYMPILDKVLPSPENALRGAGKYFGA
                     KVYANFVPHWEKETRWYFTGMGSRWKEASAYAANEKWDMAEDRWSGLYRGTENWKSRA
                     KAASNLALCHEMRGALKEAYEWAHKSYDLFKRNNGDNDKSTKLLELYVQALAERIRSD
                     KKLNVQFGED"
     gene            complement(6554..7405)
                     /locus_tag="ACZPB4_11490"
     CDS             complement(6554..7405)
                     /locus_tag="ACZPB4_11490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HIR1098870.1"
                     /translation="MKHSRRTFFKQGLAGALLLGTSTIARAALPDPVKPKAPKAVNPF
                     HLGMAGYTFVNFDLDTTLKTLERLDIHYLCIKDFHLPLNSTDEQIRAFHDKCAAHKVT
                     GYAVGPIYMKSEEEIDRAFDYAKRVGVKLIVGVPNYELLPYVDKKVKEYDFHYAIHLH
                     GPDIKTYPDATDVWEHTKDLDPRIGMCLDVGHDLRNGCDPVADLKKYHTRVFDMHIKD
                     VTDSSKAGVGIEIGRGKIDFPALIRMMREVNYTGMCSLEYEKDMKDPFLGIAESIGYF
                     KAVSDLT"
     gene            complement(7440..9410)
                     /locus_tag="ACZPB4_11495"
     CDS             complement(7440..9410)
                     /locus_tag="ACZPB4_11495"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1098871.1"
                     /translation="MKRLFFIGCWTLILTLLIPDRAKGDTFVDSLRREIKVLPDSSKL
                     IRLNELLYANTHNKVYKVYADLLLEEAQRQRNDYYKGNALLFLMRYYYMQDPDSLRIY
                     LKIAEPLFIATNRIEELCRAKGWNIYSLANEGMQGLVIREVDSLRNLATCFNYPDGVD
                     MANQALANFYFNIGLDEEGIQLSREILSRMEERNASRMRWYYVLRLLLTKDLRLEYLN
                     KLDSCIQECEKEDITQLDAEHTVAFLKDRYHYYSAQYYVAEKEPSLVYQHLRMMEDIE
                     KKNNMNAEQILPQFLWMNYYALAGKYEKAIDLANKLELMLLDKKRFSDWVSVEDFKAD
                     LYYKLGRGMEAARAYRDSKEVHDSIMRVKYYEDLAKLKTQREVEKLEIQSKKLELEAE
                     KSRVRILMLRGGFVLVLLLCAGLGIVAYARHRAGIRLKIAKEKAEEADHLKSAFLANM
                     NHEIRTPLNAIVGFSQVIADEEDAETRHELSNIIQSNNELLQRLIEDVLDISKIESNT
                     LTFVLANHEMKALMKDIYSIILLRMPENVELRLDDCQPFTLYTDRSRLTQVLTNLLTN
                     AIKHTKKGYICFGYDVTEQEIRFYVTDTGEGIPDDQLERVFDRFVKLTQWTNGVGLGL
                     AISKALVTKLGGRIEVTSQQGVGSTFSVIFPR"
     gene            complement(9596..12217)
                     /locus_tag="ACZPB4_11500"
     CDS             complement(9596..12217)
                     /locus_tag="ACZPB4_11500"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HIR1098872.1"
                     /translation="MEIASKYNPAEVEGKWYQYWLDNGFFKSKPDGREPYTIVIPPPN
                     VTGVLHMGHMLNNTIQDILVRRARMMGKNACWVPGTDHASIATEAKVVNRLAGQGIKK
                     TDLTRDEFLRHAWEWKEEHGGIILKQLRKLGASCDWDRTAFTMDEKRSESVIKVFVDL
                     YKKGLIYRGVRMVNWDPKALTALSDEEVIYKEEHSKLYYLRYKIVGEEGYAIVATTRP
                     ETIMGDTAMCINPNDPKNQHLRGKKVIVPLVGREIPVIEDDYVDIEFGTGCLKVTPAH
                     DVNDYMLGEKYNLPSIDIFNDNGTLSEAAGLYVGMDRFDVRKQIEEDLRNAGLLEKVE
                     AYENKVGFSERTNVPIEPKLSMQWFLKMEHLAQIALEPVMKDDIKFYPPKFKNTYRHW
                     MENIKDWCISRQLWWGHRIPAYFLPEGGYVVAETEEKALELAKEKCGNPNLTMSDLRQ
                     DEDVLDTWFSSWLWPISLFDGINNPDNEEINYYYPTSDLVTGPDIIFFWVARMIMAGY
                     EYRGKMPFKSVYFTGIVRDKLGRKMSKSLGNSPDPLQLIEQYGADGVRMGLMLAAPAG
                     NDIPFDDALCEQGRNFNNKIWNAFRLVKGWTVDDTIAQPEASAIAVKWFKMQLDKTIA
                     EVDDSFSKYRLSEAMMAVYKLFWDEFSSWYLEMVKPGYQQPIDKATYEATLGFFDALL
                     RLLHPFMPFITEELWQALEPRKEGESLMVAQMPEVAVADSAYLDAFEIVKEIVGGVRT
                     IRLQKNIPNKDALELQIVGEHNEAFNAVIAKMCNLSSISKVEEKAAGAVSFLVRTTEY
                     AVPLGNLINVEEELAKLQEELKYQKGFLASVMKKLGNENFVSKAPAKVIEMEKKKQAD
                     AESKIKSIEESIAALTK"
     gene            12585..13499
                     /locus_tag="ACZPB4_11505"
     CDS             12585..13499
                     /locus_tag="ACZPB4_11505"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HIR1098873.1"
                     /translation="MRKRSEYKGGDNRRKPSKERRVMVGESNTLLPFLFELLKEQSRS
                     SVKGLLSRGQISVNGKVTRQFDAPLNPNDTVGINYGRGKVEFNNPLLRIVWEDDDLIV
                     INKREGLLSVSTDRIKERTAYRILSDYLKECDPRNKIFVLHRLDRDTSGIMMFAKNQK
                     VKEQLQSNWSEAITQRTYVAVIEGRPEKDTDLIVSNLVENKHMQVYVTQDGDGKEAIT
                     RYRLLQTNNRYSLVELDLETGRKNQIRAQMQSIGHPIAGDSKYGAETNPAGRLMLHAR
                     RLCFIHPVTGEEMRFETRIPEKFTSTAK"
     gene            13521..15608
                     /locus_tag="ACZPB4_11510"
     CDS             13521..15608
                     /locus_tag="ACZPB4_11510"
                     /EC_number="1.8.-.-"
                     /EC_number="1.8.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0015036 - disulfide oxidoreductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-disulfide reductase DsbD family protein"
                     /protein_id="HIR1098874.1"
                     /translation="MKKLISSIMLALIALVVQAQILTPVKWKIKLDDKGGAPEKEIVF
                     TATADKGWHLYDMNLPEGGPVSTSFTFETLNGAELIGQPVPSVKPTTVYDEQFAMNLR
                     WYPGTVSFTQKLKVTDPAKFKAEGEVEFMACNDETCLPPDQIPFSFDKKSIHVDPALA
                     ANSSTTEVDKEDATAIQPDTQVVAEEASELNTPDPAAKETPATTSPKASDSLTDSPNL
                     WSPVIDQLKSFGDATVSAADTSWLFIFFAGFLGGLIALLTPCVWPMIPMTVSFFLKRT
                     KDRKKAIRDAITYGLSIIVIYLVMGLLITGIFGASALNDLSTNAIFNILFFLLLVVFA
                     VSFFGAFELVLPASWTSKLDSKADSTTGVLSIFFMSFTLVLVSFSCTGPIIGTLLVQA
                     ASMGTAVGPAIGMFGFALALSIPFSVFAIFPNMLQSMPKSGGWLNSVKVVLGFLELAL
                     ALKFLSVADLAYGWRLLDREAFIVLWIVIFSLLGVYLLGKIKFSHDSEVKYVSVPRLF
                     MAIISFAFAIYMVPGLWGAPLKAISAFAPPLYTQDFNLYKNEVHAAFDDYESGMAYAK
                     KVNKPVMIDFSGFGCVNCRKMEASVWTDPKVKQMLENDYVLITLMVDDKTKLPQPIEI
                     QENGKTRKLKTIGDKWSYLQRSKFGSNAQPFYILLNDEGQPLGPSYAFNEDVSKYIQF
                     LQNGLKEFKKEQQ"
     gene            15677..16462
                     /gene="mazG"
                     /locus_tag="ACZPB4_11515"
     CDS             15677..16462
                     /gene="mazG"
                     /locus_tag="ACZPB4_11515"
                     /EC_number="3.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008157145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphohydrolase"
                     /protein_id="HIR1098875.1"
                     /translation="MATREEKMEAFGQLLDILDELRVKCPWDRKQTNESLRTNTIEET
                     YELCEALMREDNTNIKKELGDLLLHIVFYSKIGEEKEAFDIKDVCDSLCQKLIYRHPH
                     VFGDTSADTAQKVEQSWEQLKLKEKGGNKTVLEGVPASLPSVVKAHRIQDKARNVGFD
                     WEQRDQVWDKVQEEFNELKTEIDRMDADKMEAEFGDLFFSLINAARLYKINPDNALER
                     TNQKFIRRFNYLEEHTIQEGRSLKDMTLEEMDQLWNEAKAKGL"
     gene            complement(16573..17046)
                     /locus_tag="ACZPB4_11520"
     CDS             complement(16573..17046)
                     /locus_tag="ACZPB4_11520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098876.1"
                     /translation="MNKIFFITFVAISVLLSFNATAQEKKEQRHFDREAFEARRNAFI
                     TAEVGLTPEEAAQFIPLCNELRQKKFEVGRECRKLSKEIRHKENPTDADYNKVIDECL
                     DVEIKEAQLEKEYFERFKKILSPEKVYKYRNAEYKFVRNFMKSGRDNKKEEKQKK"
     gene            complement(17093..17485)
                     /locus_tag="ACZPB4_11525"
     CDS             complement(17093..17485)
                     /locus_tag="ACZPB4_11525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098877.1"
                     /translation="MKKEENNLDRLKGTNPFTVPEGYMEGLTERIMSQLPEKQEERAK
                     RISLMDRVRPWLYMAAVFAGLGLFFKAIVGINGSDGSTASDSLLVRTEVPTTALDAIE
                     AEEDEEYLEYLEAQYANYLLDEELSYSE"
     gene            complement(17533..18084)
                     /locus_tag="ACZPB4_11530"
     CDS             complement(17533..18084)
                     /locus_tag="ACZPB4_11530"
                     /inference="COORDINATES: protein motif:HMM:TIGR02937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HIR1098878.1"
                     /translation="MQSYTEDEIVVQLRDPARQREAFAKVVSLYGEKLYWHIRKMVLD
                     HEDANDLLQNTFLKAWTNIELFRGEAKLSTWLYKIAINECITFLNKQRNMNNVSIDDA
                     DTFLLDRLKGDEYFDGDEIQVRLQNAILTLPEKQRLVFNMKYNEEMKYEEMSEILGTS
                     VGALKASYHHAVKKIEEFLTKEV"
     gene            complement(18103..18186)
                     /locus_tag="ACZPB4_11535"
     tRNA            complement(18103..18186)
                     /locus_tag="ACZPB4_11535"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(18150..18152),aa:Leu,seq:cag)
     gene            complement(18330..19970)
                     /gene="groL"
                     /locus_tag="ACZPB4_11540"
     CDS             complement(18330..19970)
                     /gene="groL"
                     /locus_tag="ACZPB4_11540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005941147.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HIR1098879.1"
                     /translation="MAKEIKYDMDARDLLKKGVDELANAVKVTLGPKGRNVIIEKKFG
                     APHITKDGVTVAKEVELTCPFENMGAQLVKEVASKTNDNAGDGTTTATVLAQSIIGVG
                     LKNVTAGANPMDLKRGIDKAVAKVVESIANQAEAVGDKFEKIEHVAKISANGDEAIGK
                     LIAEAMQRVKTEGVITVEEAKGTETTVDVVEGMQFDRGYISPYFVTDTEKMECQMENP
                     YILIYDKKISVLKDLLPILEPTVQSGRPLLIIAEDIDSEALATLVVNRLRGSLKICAV
                     KAPGFGDRRKAMLEDIAVLTGGTVISEEKGLKLEGATMDMLGTAEKITVDKDTTTIVN
                     GAGDKEAIQARIGQIKIQMENTTSDYDKEKLQERLAKMAGGVAVLYVGAPSEVEMKEK
                     KDRVDDALHATRAAIEEGTVPGGGVAYIRAIDALEGMKGDNEDETTGIEIVKRAIEEP
                     LRQIVANAGKEGAVIVQKVKEGKGDFGYNARKDCFENLCEAGVIDPAKVTRVALENAA
                     SIAGMFLTTECVIAEKKEETPAMPPMNPGMGGGMGGMM"
     gene            complement(20011..20280)
                     /locus_tag="ACZPB4_11545"
     CDS             complement(20011..20280)
                     /locus_tag="ACZPB4_11545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HIR1098880.1"
                     /translation="MNIRPLADRVLIKPAAAEEKTLGGIIIPDSAKEKPLKGEIVAVG
                     NGTKDEEMVVKVGDNVLYGKYAGTEIELDGEKYLIMRQADVLAII"
     gene            complement(20469..>21716)
                     /locus_tag="ACZPB4_11550"
     CDS             complement(20469..>21716)
                     /locus_tag="ACZPB4_11550"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004348 - glucosylceramidase activity
                     [Evidence IEA];
                     GO_process: GO:0006665 - sphingolipid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 30 protein"
                     /protein_id="HIR1098881.1"
                     /translation="QQIDGFGACFNELGWLSLSKLEPSVREEIMEELFFPGVGANFTI
                     CRMPVGANDFSRDWYSYDEVDGDFTMEHFTIANDQQTLIPFIKNAQKYQPDLRLWASP
                     WCPPAWMKYNKHYASAYTGENYDEKYRNGLPADKVGHEGTDMFIQDPLYLKAYALYFS
                     KFIEAYKKQGIPIFAVMPQNEFNSAQIFPSCCWTSASLANFIGNYLGPAMQVQGVEIM
                     FGTMERANESLVDTVLTDPVSGKYVKGVGFQWAGKGAITGIHKRYPGLKLYQTEQECG
                     DGKNDWKGAMYSWGLMRHFLDNGVSAYMYWNISLENGGISRWGWEQNSLVVVDPQTKS
                     YRYTPEYYVMKHVSHYVQPGAYKLETEGAYTNLLAFRNPDNSIALIIANETSDDHSLS
                     IRIGDRVYTPIVKAYSMNTLLVD"
BASE COUNT         5952 a         5498 c         4405 g         5861 t
ORIGIN      
        1 tcgacgatat acttacccaa tcccaaggcg atattcgcga tcccatcttc cgccttctcg
       61 ttaccgatcg gatagaaatt caaggaacgg gccacgcccg acatcgtcgg atagaaatga
      121 tcattataac gggagcccac cacttcttgc aagacgatag ccatcttctc ctgatcgatc
      181 aagttcgagg tagccgtcat atacgcctta ctatccttat aaaagacaga ggcatacacc
      241 gccttgatag cgtcgctcac cgtacggagc atatcgtatt tctcctcgat cttaggtacc
      301 atatacgtag aatagatccc ggcgaaaggt tgataatgcg aatcttccag caggctggag
      361 gaacgcacgg cgatcgggct tttcaccaca tcgaagaaag ccatcaagtc ctcgattaaa
      421 cgggagggca agctggcccg caagaaatac cggaggatcg tctcgtcgtc cgcatcgccc
      481 agcgctaccg gatacaactc gttcgtctcc atgaactcgt cgaagatatc ggtacagatc
      541 acgaccgtct tcgggatatt cacggcaaaa ttatcactct ccagcttagg gtatcgcttc
      601 accatcgcac cgataaaggc aagacctcta cccttacctc ccagcgaacc gtcgccgata
      661 cgggcaaaat tactatactc atcaaaacga tccttctgat aaaccgccac gacacccgtg
      721 ttcttcatcc ggcgatattg cacgatcaag tcgaaaatca atttccgggc ctcatccata
      781 tccttatagt cactcacgtc cacatgcttc aaaacctcgg cgggcggaaa catggcacgg
      841 gaataaaaga aacgggagaa atgattccgg gagagatggt aaaccagcga gtcgtcggga
      901 atctgaaaga ctttcttttg aaggtctttc aaatccttga tgcgcatgat ctcctctttc
      961 gtatgcggat tcaagatcac gaaatcgccg aaaccgaaac gctgcatgat cttctttttc
     1021 aaatcctgcg gataactctt ggaattctta tcgataaacg aggcgttcag ttccttcgcg
     1081 tacacatggt tgctggcctc cgaagattcc agcacgaaag gaatgatcaa acccgttttc
     1141 cgtacatact gtccgaactt ataaccggca tacggatctt tcacgccatt gtgcataaaa
     1201 ctcatatccg agataatacc caacatatta tcccgatact gatcaaaaat acgtaccgcc
     1261 tcctcgtaat tccgggccaa tttgatcttc ggacgacccc gcatacgcaa cgtacgctgg
     1321 tgatcgttca acgcctcctt cgcgaacatt tggctctgct ccagcacgaa cttatataaa
     1381 tgaggcaaag cggacgaata gaaacgaatg gaatcctcca ccaacaagat gatctgtacg
     1441 cccacgctgg ccgtatcgtc cggagcgttc atcttatcct cgatcaactt gataatcgcc
     1501 agtaacaact ccgagttacc caaccagctg aacacataat cgatagcgct cagatcctcg
     1561 ttggcgatcc gcttagacac ctctttcgag aaaggagtca atacaacgat cgggatattc
     1621 ggataatgca cctttatctc gctcgccgca gcgaatatat cccggttatc catattcggc
     1681 atgcaaatga tcaattcgaa gttccggttc ttcaactcat tcaaagcctc ctcctcggta
     1741 gtcacctgcg taaaccgggg tgggtaacgg aggcttaagg aagtatattc gttaaatatc
     1801 tgctcatcta cacgcccgtc atcttccagc atgaaggaat catatttcgt agcgataagc
     1861 aatacattat atatacgctt attcattaga ttggcaaacg gggtgtctct gaacaccaag
     1921 tcttttaagt tcggtatacc gctcataata gattctgata gaattattcg agtcaaatgt
     1981 aaggaaaaat aataactatt gaaacatgaa agtacgcatt ctgactctaa ctgaagattt
     2041 ttaggttttc actgataaaa agtaagcgaa actcttggcc attccaaaga attacctaca
     2101 tttgccaaca gaatgttatc cttttaaaga atataaatgc tatgaagact gaagttattt
     2161 tatcagcgct agaggcaaaa catccgggag aaaaggagta tttgcaagca gtaaaagaag
     2221 tgcttttatc aattgaggaa gtgtacaacc aacatccgga atttgagaaa gcgaaaatca
     2281 ttgaacgcct agttgagccg gaacgtattt tcactttccg tgtgccttgg gtagatgata
     2341 aaggtgagat acaagttaac ttgggatacc gtgttcagtt caacaacgcg atcggcccgt
     2401 acaagggagg tatccgtttc cacccgtccg ttaacttgtc tatcttgaaa ttcttaggat
     2461 tcgagcaaac atttaaaaac gctttgacaa cccttccgat gggtggtggc aaaggtggtt
     2521 ccgatttcgc tccgagagga aagagcgacg ccgagatcat gcgtttctgc caagcgttta
     2581 ttcttgaatt atggcgtaat cttggtccgg acagggatgt tccggctggc gatataggcg
     2641 taggtggccg tgaggttggt tatatgtacg gtatgtacaa gaaattggct cgcgagaaca
     2701 caggtacgtt cacgggtaag ggcatggagt tcggaggttc tatccttcgt ccggaagcta
     2761 ccggcttcgg cgctctttat ttcgtacatc aaatgctgga gactcacgga atcgatatca
     2821 aggacaagac ggtcgccatc tccggtttcg gcaacgtggc ttggggtgcc gcaacaaagg
     2881 caaccgagtt gggcgctaaa gtggttacta tctccggtcc tgacggatat atctatgatc
     2941 cggcgggtat ctccggcgag aagatcgact atatgttgga attgcgtaat tccggaaatg
     3001 atatcgtagc tccttacgca gacgaattcc cgggctctac cttctatccc ggcaagaaac
     3061 cttgggaaca aaaagtagat atagccttgc catgcgctac ccagaatgag ttgaacgagg
     3121 ctgacgctcg taagttgatc gagaacaaga ctttgtgcgt agctgaggtt tctaacatgg
     3181 gttgtacggc tgaggctgta gacttgttca tcgagcataa gcaattattc gctccgggta
     3241 aggcagtcaa cgccggtggt gtggctactt ccggattgga gatgacccag aacgctatgc
     3301 atatctcatg gactgccgcc gaggtagacg ctaaattaca tcagatcatg agcgcaatcc
     3361 acgaacaatg cgtagctcat ggtaaagatg gcgaatatat caattatgta aaaggcgcga
     3421 atatcgcagg cttcatgaaa gtagcgaaag ctatgatggc tcaaggtatc gtataagaat
     3481 aaggtcagtt taggctaaat aaaaacatag ttatgaattc tttgaacctt agttatggtt
     3541 tgagaatttc ataactatgt tttttaagct catatcagcg gactttcccg gggttcttag
     3601 cgataaaatc cttccatccc gtatacttct tttccgagat cggattattg gtttggaaat
     3661 aatgacaaac agccgccgcc aacccatccg tagcgtccaa ttgcggaagc atagactcat
     3721 ccggtatctt cagatagcgt tgtagcatgc cggccacttg ttctttcgcc gcatttccat
     3781 tccccgtgat cgagagcttg atttttagag gggcgtactc gaagatcggg acatcccgct
     3841 ctaaagccgc cgccatcgct actccttgtg cccttccgag tttcaacata ctctgtacgt
     3901 tcttcccgaa gaaaggcgcc tcgatagcca actcatccgg atggtattga tcgatcaagg
     3961 ccaagacccg ttcgaatatc ttacgcagac ggagataatg atcctcatat ttattcaatt
     4021 gcaggattcc catagcttcc agcttcggtt tattcccctc gatcttcaag attccgtatc
     4081 ccatcacgat cgtaccgggg tctatgccta atataatacg gtccttgatc atttaggtag
     4141 ctctatatct tccaacaggg tagagaatcc tgcgattttc tctttataac gtcctatcaa
     4201 atcttgctgc aaggctccgc cttccttacg cacccactca ttcaacgaat cgatatccct
     4261 cgtatgaaac tgtacggaaa aactttcacc ttcctcattc cgcgaatcca agatccgtct
     4321 caaataagga ctataaagga taccgctctc ggaggctttc ggtatataac tattcttcaa
     4381 atattccaga cactcatcca cgatatcctt atggatatga aaagtcgtat tataaattat
     4441 catcttcttt cctttctctt gaaatttctt atacaaagat agcgcatata tcaagaaaag
     4501 ccttatattt gcacatgaat taacaagacg gggcattagc tcatctggct agagcgacag
     4561 actggcagtc tgtaggtgat cggttcgagt ccgatatgct ccaccaataa taaattaagc
     4621 ggttacaaaa caagtagccg ctttttttat tgataaaaat cgttttgttt tggcgttttg
     4681 ttgcatttgg tgacgcaaat ttgacgcaaa taataacgct gttgcgttca ttgcatttcc
     4741 ggtttaacac ccagtttaac cttacctccc aaacctcgct agaaccgcag ccttatcaaa
     4801 caaaattagg cagttaccta aaaagataac tgcctaattt tgtgagccga aagccggact
     4861 tgaaccggcg acctacgcat tacgaatgcg ttgctctacc agctgagcta tttcggcaac
     4921 atttgtttct ttatttcggg cgcaaagata cagggtttat ttgacatctg caagaagatt
     4981 cgctaaaaaa tcatctaaat ctgcatctaa atcttttaat agaggatcgt ccagacgaag
     5041 catatcatca tcgatgaaga gaagttcctc tattacaaca aaatcctcat cggtcaagct
     5101 aacagaaaga ggcttcatga atcgggggac gtcaaaaata ttcttggtag acaagatcgt
     5161 aagaaccgcc ttcaccgaag cggcaacccg cttattgaat gcgttctcct cctcgttcga
     5221 gttcacccaa tcgaagataa cgatcttttc gatcaaatgc tcctcatcat cataaatttg
     5281 cagttccccg ctttccgcat cagcctgcac atataagtcg cttataaaat taccggactc
     5341 atccttggcc agcttttcaa cagccgacgt aaaagcgttc tcgatgaggg attgaacctt
     5401 tgccatattt gcgttcatat attaattctc ctttattcga atatgcgtca aaagtaataa
     5461 taattcaccg aataacgccg ttaatcctca ccaaattgca catttagttt cttatcggaa
     5521 cgaattcgtt cggccaacgc ctgtacatag agttccaata atttggtact cttatcatta
     5581 tcaccattat tacgcttgaa taaatcgtat gatttatgag cccactcata ggcttctttt
     5641 aaagctcctc tcatctcatg gcatagggcc agattagagg ccgccttcgc ccggcttttc
     5701 cagttttccg taccccggta aagcccggac caacgatctt ccgccatatc ccatttctca
     5761 ttagccgcat aagcggaagc ctctttccaa cgtgaaccca ttccggtaaa gtaccaacga
     5821 gtctccttct cccaatgagg aacaaaatta gcgtagacct tcgccccgaa atatttaccg
     5881 gccccacgca aagcattctc cggagagggc aataccttat ccaagatcgg catataatcc
     5941 gcactttccg cccaataaat actatctttc atatgtaccg tcgccagtgg agcctcacga
     6001 tcgggaacgt aactgcgtat cacgccagcc atctgcacgt cgatcattcc cattacatac
     6061 ccttcgccca aggtacctac gcttttcttc atatcgaaca gcaagcggtc gatggagata
     6121 accgcatcgg caccggtctc atcgcatagc gacgctactt gcccttgggt aagtttcgta
     6181 tccagaaacg cctgattatc ctttcgaacc ccatcatggt aaagcaatac gtcgttaaaa
     6241 taagaagcct ccacgatagc ctcccctaaa gtacggcaag cgtcaaacag cgcactatcc
     6301 gctttcgctt tgcaagtatc ctgcttttct ccctgcaagg tgtattcgta acccgcatcc
     6361 tctggttggg ggacggcatt gtttacgata agtaccttgg cgacattctc aggaaacgtc
     6421 acctccgcag gattatacgt ctcgatacct acataattaa tcgtgctaca agcggacaac
     6481 aaacccgcta tgcctataaa aagaatgctt ctcatcttca tctatttaaa agggggcgat
     6541 ttacgccccc acattatgtc aaatcactca cagccttgaa atagccgata gactccgcga
     6601 tccccaagaa ggggtctttc atgtctttct cgtattccaa gctacacatt cccgtgtaat
     6661 taacttcccg catcatacgg atcagcgcag ggaagtcgat ctttccacga ccgatctcga
     6721 tcccgactcc cgccttcgaa gaatccgtca cgtccttgat gtgcatatcg aatacccggg
     6781 tatggtattt cttcaagtcg gcgacaggat cacagccgtt tcgcaagtca tgcccgacat
     6841 ccagacacat accgatacgg gggtctaaat ccttcgtatg ctcccaaacg tccgtagcat
     6901 cgggatacgt cttaatatca ggaccgtgca agtggatagc gtaatgaaaa tcatactcct
     6961 tcactttttt atccacatag ggtaaaagct cgtaattcgg gacaccgacg attaacttca
     7021 ctcctacccg cttcgcataa tcaaacgcac gatctatctc ttcctcactc ttcatataaa
     7081 taggacctac ggcatatccc gtcactttat gggcagcgca tttatcatga aaagccctaa
     7141 tctgctcatc cgtactattc aacggcaaat ggaaatcctt gatgcaaaga taatggatat
     7201 ctaatcgttc caacgtcttc aacgtcgtat ctaaatcaaa attaacgaaa gtatatcccg
     7261 ccattcccag atggaacggg tttacggcct tcggggcttt tggctttaca gggtccggca
     7321 aagcggcccg ggcgatcgtg gaggtaccta ataaaagggc acccgccaat ccttgtttaa
     7381 aaaatgtacg tcttgagtgt ttcatggtct attacaatat tatatataat gtatactgtt
     7441 tatcttggga aaataacgct aaaggtagag cctacccctt gctgggaagt cacttctata
     7501 cgaccgccga gctttgtgac caaagccttg gagatagcca atcccaagcc gactccattg
     7561 gtccattgcg tcaacttgac aaaacgatcg aaaacccgtt ccaattggtc gtccgggatt
     7621 ccctcgcctg tatccgtcac ataaaagcgg atttcctgct ccgtcacgtc atacccgaag
     7681 caaatataac cttttttcgt gtgcttgata gcattcgtca ataaattagt gaggacttgc
     7741 gttaatctac tccgatcggt ataaagcgta aaaggttggc aatcatccaa tcgaagttct
     7801 acattttcgg gcatacgtaa taaaatgata ctatagatat ctttcattaa agccttcatt
     7861 tcatgattcg ccaaaacgaa agtcaacgta ttcgactcga ttttcgatat atccaatacg
     7921 tcttctatca agcgttgcaa caattcatta ttactttgta taatattgga gagttcatga
     7981 cgagtttccg catcttcctc atcggcgatc acctgcgaga atccgacgat ggcgttcaat
     8041 ggcgtcctga tctcatgatt catgtttgcc aagaacgcag atttcaggtg atccgcctcc
     8101 tccgctttct cttttgcgat ctttaatcgt atccccgcac gatgacgggc ataggcgact
     8161 atacccaagc ccgcacatag taacaacacc aagacaaatc ctcctcgaag catcaagata
     8221 cggacacgcg acttttccgc ctctagctcc agtttcttac tttgtatctc tagtttttcc
     8281 acctctcgtt gggttttcaa cttcgctaaa tcctcgtaat attttacccg cataatcgag
     8341 tcgtgcactt ctttagaatc tctgtaagcc ctagccgctt ccatccctct tccaagctta
     8401 taatagagat ccgccttaaa atcctccact gagacccaat cactaaagcg tttcttatcc
     8461 aagagcatta gttccaattt gttcgccaaa tcaatggcct tctcatattt ccccgctaaa
     8521 gcgtaataat tcatccaaag gaattgaggc aggatttgct cggcattcat attattcttc
     8581 ttttcgatat cctccatcat cctcaagtgc tgataaacca aggaaggctc tttttccgcc
     8641 acgtaatact gggccgagta ataatgatag cgatctttta aaaaagcgac agtatgttcc
     8701 gcatccaatt gagtaatgtc ctctttctcg cactcttgta tgcaagaatc caatttattc
     8761 aaatactcca atcgcaaatc cttcgtaagc aacagccgta acacgtaata ccaacgcatc
     8821 ctagaggcat tacgttcttc catgcgagat aagatctccc ggcttaattg aataccctcc
     8881 tcatccaatc ctatattaaa atagaaattc gctaaagctt ggtttgccat atccacccca
     8941 tccggataat taaaacaggt cgcaagattc ctcaagctat ccacctcccg gattaccaat
     9001 ccctgcatcc cctcattcgc taaagaatag atattccatc ctttcgccct acataattcc
     9061 tcgatccggt ttgtcgcgat gaaaaggggt tccgctattt tcaaatatat tcgcaagcta
     9121 tccggatctt gcatatagta ataacgcatc aagaatagta aggcatttcc tttgtaataa
     9181 tcgttacgtt gcctctgtgc ctcttctagt agcaaatccg catatacttt atatactttg
     9241 ttatgcgtat tggcataaag taattcgttc aagcgtatta gtttactact atccggcaaa
     9301 accttgattt ctcttcgtaa gctatcgaca aacgtgtcac ctttcgccct atccggaata
     9361 agcaaagtta gaatcaacgt ccaacaacca ataaaaaaca atctcttcat atataccttg
     9421 aaaagttagc acgactatcc attattcaat gcccggcaag ttaataaaaa tttaaatgcc
     9481 aagacatcaa cataaacaag tttaatatca cattttcaac ttatacaaca aaaagcctat
     9541 atcaaccaaa aaaagattga tataggctct tatttcaaag aaacggccgt tctatttatt
     9601 ttgtcaaggc agcgatactt tcctcgatag acttaatctt cgattcggca tcggcttgct
     9661 ttttcttctc catctcgatt actttcgccg gggctttgct cacgaagttc tcattgccta
     9721 atttcttcat gacagaagcc aagaaacctt tttggtattt caattcttct tgaagcttag
     9781 ccaactcttc ctccacattg atcagattgc ctaaaggtac ggcatattca gtcgtacgga
     9841 ccaagaacga tacagcaccg gccgctttct cctctacctt ggagatggaa gagagattgc
     9901 acatcttagc gattacggcg ttgaacgcct cattgtgctc acccacgatc tgcaattcca
     9961 gcgcatcctt attcggtata ttcttttgca aacgaatggt acggacacca ccaacgatct
    10021 ctttcacgat ctcgaaagca tccaaataag cgctatccgc aacagctact tccggcattt
    10081 gggcaaccat caagctctca ccttccttac gaggctcaag ggcttgccat aattcctcgg
    10141 taataaacgg catgaaagga tgaagcaaac gaagcaaggc atcgaagaaa cctaacgtag
    10201 cctcataagt agccttgtcg atcggctgct gataccccgg ttttaccatc tccagatacc
    10261 atgaggagaa ctcatcccag aacaatttat agacagccat catcgcttcg ctcagacgat
    10321 atttactgaa agagtcgtct acctcggcaa tcgtcttatc cagctgcatc ttgaaccatt
    10381 tcacggcgat agcggaagcc tccggctgag cgatcgtatc gtctaccgtc cagcccttca
    10441 ccaagcggaa agcattccat atcttattat tgaagttacg tccttgctca cacaaagcat
    10501 catcgaaagg aatatcattt ccggcaggag ccgcgagcat caagcccata cgcacgccgt
    10561 ccgcaccgta ttgctcgatc aattgcaacg gatcgggaga gtttcctaaa gatttggaca
    10621 tcttacgtcc cagcttatcg cgaacgatac ccgtaaagta gacgctcttg aacggcattt
    10681 tccctctgta ctcatagccg gccataatca tacgggctac ccagaagaag atgatatccg
    10741 gtccggttac caaatcactg gtcggatagt aataattgat ttcctcgtta tccgggttat
    10801 tgataccgtc gaacagggag atcggccaca accaagagga gaaccaagta tccaatacgt
    10861 cctcgtcctg acgcaaatca gacatggtca gattcgggtt accacatttc tctttcgcca
    10921 gttccaaagc tttctcttcc gtctcggcta ccacgtaacc accttccggc aagaagtaag
    10981 ccgggatacg gtgtccccac caaagctgac ggctgataca ccagtccttg atattctcca
    11041 tccaatggcg gtaggtgttc ttgaacttcg gcggatagaa cttgatatcg tccttcatga
    11101 ccggctccaa ggcgatctgg gctagatgtt ccatcttcaa gaaccattgc atagacaatt
    11161 tcggttcgat aggcacgttc gtacgctccg agaagcccac cttgttctcg taagcctcta
    11221 ccttctccaa aagaccggcg ttacgcaagt cttcctcgat ttgcttgcgg acatcaaaac
    11281 gatccatgcc cacgtacagg ccagcggcct cgctcagcgt accgttatcg ttgaatatat
    11341 cgatagaagg caaattatat ttctcgccca acatatagtc gtttacatcg tgtgccgggg
    11401 tcactttcaa acagcccgta ccgaactcta tatctacgta atcatcctcg atcaccggaa
    11461 tctcacggcc taccagcgga acgatcactt tctttcctct cagatgttgg ttcttcgggt
    11521 cgttcgggtt gatacacatc gccgtatctc ccataatcgt ctccggacgg gtagtggcga
    11581 caatggcgta tccctcctcg cctacgatct tatagcgaag atagtacaac ttactatgct
    11641 cttccttata gataacctcc tcatcggaca gggccgtcaa cgccttcggg tcccaattca
    11701 ccatacggac accccggtag atcaaacctt tcttatatag atcgacaaaa accttgataa
    11761 cgctctccga acgtttctcg tccatcgtga acgccgtacg atcccaatcg caggaagcac
    11821 ccaatttacg aagttgcttc aagataatgc cgccatgctc ttctttccat tcccaagcat
    11881 gccgcaaaaa ctcgtcgcga gtcagatcgg tcttcttgat tccttgcccg gccaaacgat
    11941 tcaccacttt cgcctccgtt gcgatcgaag catggtccgt acccggtacc caacaagcgt
    12001 tcttacccat catacgggca cggcgaacca agatatcttg gatcgtattg ttaagcatat
    12061 gtcccatgtg caatacgccg gtgacgttag ggggcgggat tacaatcgta tacggctcac
    12121 ggccgtctgg ctttgactta aagaagccgt tatccaacca atactgatac cacttcccct
    12181 ctacttcagc gggattgtac ttactagcga tttccatatt tttataacta attagtcttt
    12241 acacatttct cgatccgcga aagtacaaaa aatatagaca aaaaacgctg agcatcggga
    12301 aatatagtcg gccgagacaa taggcattcc ctctcggaca cgccactatt ctacaaacca
    12361 cgacgtggtt tatacagacc aagccgtgga ttgtacagat cacgacgtga tttataagga
    12421 ccacgccgct attttgaaaa tagagtgaat ggcaattact tttacatccg gggatttgaa
    12481 ggtttattcc tataacaagc aaactattta taacggtttt tctattccgc actattgcag
    12541 tttcgcgtaa atgcctgtat cttcgcgtac tataaaaaat agatatgaga aagcgatctg
    12601 agtataaagg aggggataat cgacgtaaac cctctaaaga acgacgggta atggtaggtg
    12661 aaagtaacac tttgctacct ttcctgttcg agttattaaa agaacagagc cgttcatccg
    12721 tgaaaggatt attgagcagg ggacagatct cggtaaacgg gaaagtcacc cggcagttcg
    12781 atgccccgct gaaccctaac gatacggtcg gaatcaacta tggaagaggg aaggtagaat
    12841 tcaacaatcc gttacttaga attgtttggg aagatgatga cctcatcgtg atcaacaagc
    12901 gggaaggttt gctatccgta tctaccgatc gtatcaaaga gcgtacggcc taccgtatcc
    12961 tgagcgatta cttgaaagaa tgcgaccctc gcaacaagat attcgtcttg caccgtctgg
    13021 accgagacac atcgggtatc atgatgttcg ccaagaacca gaaggtaaaa gagcaactac
    13081 agtccaactg gagcgaggct atcacgcaac ggacctacgt ggccgtgata gagggacggc
    13141 cggagaaaga cacggatttg atcgtatcca acctcgtgga gaacaagcat atgcaagtgt
    13201 acgtgacaca agatggtgac ggaaaggaag cgatcacacg ctaccgactc ctgcaaacga
    13261 acaatcgtta ttcgctcgtg gaactcgatc tggagacggg acgcaagaac caaatccgtg
    13321 cgcagatgca atccatcggg catccgatag ccggagactc taaatatggg gcggagacaa
    13381 atcctgccgg acgcttgatg ctccatgccc gcaggctctg tttcatccat ccggtaacag
    13441 gcgaggagat gcgcttcgag acacggatcc cggagaaatt cacatcgaca gcaaagtaat
    13501 ctatcaataa aggacaaaaa atgaagaaac tcatcagttc gatcatgctg gcgctaatag
    13561 cgctggtagt gcaggcgcaa atacttacgc ctgtcaagtg gaaaattaaa ctagacgaca
    13621 agggcggcgc acccgagaaa gagatcgtct ttaccgccac ggcggacaaa ggttggcacc
    13681 tgtatgacat gaacctgccg gaaggaggtc ctgtttctac atctttcaca ttcgagacat
    13741 tgaatggagc tgaactgatc ggtcaaccgg ttccttcggt aaagccgacc acggtttacg
    13801 acgagcaatt tgccatgaat cttcgttggt atccgggtac ggtatcgttc acccaaaaac
    13861 taaaggttac cgatcccgct aaattcaagg cggagggcga ggtggaattt atggcttgta
    13921 atgacgagac ttgtcttccc ccggatcaaa tacctttctc tttcgataag aaaagtatcc
    13981 atgtagatcc agctctggca gctaacagct cgactacaga ggtggataaa gaggacgcca
    14041 cggccataca gccggatacg caagtcgtag cggaagaggc cagcgagttg aacactccgg
    14101 accctgccgc taaagagaca ccggctacga catctcctaa agcgtccgac agcttaaccg
    14161 atagcccgaa tctttggtct ccggtgatcg accaattgaa atcgttcggc gacgctacgg
    14221 tatcggcggc ggatacctct tggttattca tcttcttcgc aggtttcttg ggaggtttga
    14281 tcgccttatt gactccttgc gtttggccga tgatccctat gacggttagc ttcttcctga
    14341 aacgtacgaa agatcgtaag aaagcgattc gcgacgctat cacctatggg ttatctatta
    14401 tcgtaatcta tttggtgatg ggcttgttga tcaccggtat cttcggagcg agcgcattga
    14461 atgatttatc aacgaacgcg atctttaata tcctgttctt cttgctgttg gtagtattcg
    14521 cagtctcctt cttcggagcc ttcgagctgg tattacctgc gtcatggact agcaaattgg
    14581 atagcaaggc cgattcaacg accggcgtat tgagtatttt ctttatgtcg ttcacgttgg
    14641 tattggtatc tttctcttgt acgggtccga ttatcggaac cttgttggtg caggcagctt
    14701 ctatgggtac ggcggtagga ccggctatcg gtatgttcgg tttcgccttg gcgttatcca
    14761 tcccgttcag cgtcttcgcc atcttcccga atatgctgca aagtatgccg aaatccggcg
    14821 gatggttgaa ttccgtgaag gtcgtattgg gcttcttgga gttggccttg gccttgaagt
    14881 tcctttccgt agcggactta gcgtatggtt ggcgtttact agaccgtgag gcttttatcg
    14941 tgctttggat cgtgatcttc agtttattgg gtgtttactt attaggaaag atcaagttta
    15001 gccatgatag cgaagtaaaa tatgtatctg ttcctcgtct gtttatggcg attatctctt
    15061 tcgctttcgc catttacatg gttccgggac tttggggcgc tccgttaaag gcgatcagcg
    15121 cattcgctcc tccgttgtat acacaagatt tcaatctata caaaaacgag gtacacgccg
    15181 cgttcgacga ttatgaatcc ggtatggctt atgccaagaa ggtaaataaa cccgtcatga
    15241 tcgacttctc cggtttcggt tgcgtaaact gccgtaagat ggaggcttcc gtttggacgg
    15301 atcctaaggt gaagcaaatg ctagaaaatg attacgtgct aatcactctc atggtagacg
    15361 ataagacgaa actcccgcaa cccatcgaga tccaagagaa cggaaagact cgtaagctga
    15421 agacgatcgg tgataaatgg agttatttgc aacgaagcaa gttcggttct aatgcccagc
    15481 cattctacat cttattgaat gacgagggac agccgctcgg accttcatac gcattcaatg
    15541 aggatgtttc caaatacatc cagttccttc aaaacggatt gaaagaattc aagaaagaac
    15601 aacaataaaa caaacagagg gccgggttct accctgccct ctttctttta caatcattat
    15661 agaataagta aataatatgg caactagaga agagaagatg gaagccttcg ggcaattact
    15721 cgacattctg gatgaattac gggtaaaatg cccttgggat cgtaaacaga caaacgagag
    15781 cctccgcacg aatacgatcg aggaaaccta tgaactatgc gaggccttga tgcgtgagga
    15841 taacacaaac ataaaaaaag aattaggaga cctgttattg cacatcgtct tttactccaa
    15901 gatcggcgag gaaaaagaag ctttcgatat caaggatgtc tgcgacagcc tttgccagaa
    15961 actgatttac cgccatccac acgtattcgg agatacctcc gccgataccg ctcaaaaggt
    16021 agagcaaagc tgggagcagc ttaagttgaa agaaaagggg ggtaacaaaa ccgtactgga
    16081 gggtgttccc gcttccctcc catccgtagt aaaagcgcat cgtatccaag ataaggcccg
    16141 taacgtaggt ttcgactggg aacaacgtga tcaagtatgg gataaggtac aggaggaatt
    16201 taatgagttg aaaaccgaga tagacaggat ggacgcagat aagatggaag ctgagttcgg
    16261 agatctcttc tttagcttga tcaacgctgc ccgcctatac aaaataaatc cggacaacgc
    16321 attggaacgc acgaaccaga agtttatccg ccgttttaat tatctagagg agcacacgat
    16381 ccaagaaggt cgttccttga aagatatgac attggaggaa atggatcaac tgtggaatga
    16441 agccaaggcc aaaggcttat aaagcaagga taagggcaaa acaaaagggg aaccgacatc
    16501 acgtcgccac ccctccctta acttaaacgc caaaactaaa tctaaacaaa aaacacaaat
    16561 aatgataata ttttactttt tctgtttttc ttccttttta ttgtcccgac cactcttcat
    16621 gaaattccgg acaaacttat attccgcatt tcggtactta tagacctttt cgggagaaag
    16681 tatcttcttg aatctctcaa aatactcttt ttccaactgt gcctctttta tctcaacatc
    16741 cagacattcg tctatcactt tgttataatc agcatctgtc ggattctcct tatgtcgaat
    16801 ttcttttgat aacttacgac attcacgacc tacctcaaat tttttctgtc gcaactcatt
    16861 gcataaagga ataaattgtg cagcttcctc aggtgtaagg ccaacttcag ccgtaataaa
    16921 agcattccgc cttgcttcga atgcctctct atcaaaatgt ctttgctctt tcttctcttg
    16981 tgccgtagca ttgaaagaga gtagaaccga aatcgctaca aatgtaatga aaaatatttt
    17041 attcatacaa gtattattac aaaaatcttc gataaaatta ctattttaaa ctttattcag
    17101 aataggaaag ttcctcatct aagagataat tggcgtactg agcttccaaa tactccaaat
    17161 actcctcatc ttcttccgct tcaatagcgt ctaaagccgt tgtcgggact tccgtccgga
    17221 ccagtaaaga atcagacgca gtactaccat cggaaccgtt tattcccacg atagccttga
    17281 aaaacaaacc aagaccagcg aataccgcag ccatgtacaa ccacggacga acacgatcca
    17341 tcaaggaaat ccgtttcgcc ctctcctcct gcttctcggg gagctgactc atgatccgct
    17401 ccgtaagccc ttccatatac ccttccggta cagtgaaagg attagttcct ttcaagcgat
    17461 ctaggttgtt ttcttctttt ttcatacttt ttctcttttt atattgcttt gacagcgatt
    17521 cgggcaaaag gtttaaacct cttttgttaa aaactcctcg atttttttca ccgcatgatg
    17581 atacgaggcc ttcaaagccc cgacagaggt acctagtatc tcggacatct cctcgtactt
    17641 catctcctcg ttatacttca tattgaaaac caagcgttgt ttctccggca aggtaagaat
    17701 agcgttttgc aatcttacct gtatctcgtc accatcgaag tattcatcac ctttcaaacg
    17761 atccagcaaa aaggtatccg catcgtcgat agatacgtta ttcatatttc gctgtttatt
    17821 caggaaagta atgcactcgt tgatcgcgat cttataaagc catgtagata atttggcctc
    17881 accacgaaaa agctcgatgt tcgtccaagc tttcaaaaat gtattttgga gtaagtcgtt
    17941 cgcatcctca tgatccagta ccatctttcg tatatgccaa tacaacttct cgccatacaa
    18001 gcttacgacc ttggcaaagg cctcacgttg tcgggccggg tcccggagct gtactacaat
    18061 ttcgtcttct gtataggatt gcattttttc tattttggga agtgcccaga acaggactcg
    18121 aacctgcacg atcgcaaaac cactcgcacc tgaaacgagc gcgtctacca attccgccac
    18181 ctgggctttt tttaatcatt ctgaagcgca acctatcggt attgcgcata caaaggtaat
    18241 cgttttttcc aattagcaag caaatgaaaa taaaaaaagc gaccgtccct tccggaacgg
    18301 ccgcccatat cattaatcac gggagtcgat tacatcatac cacccattcc gccgcccata
    18361 cccggattca tcggaggcat agcaggagtc tcttcttttt tctcagcgat cacgcactca
    18421 gtagtcaaga acatacctgc gatagaagca gcgttctcca atgctacgcg agttacctta
    18481 gctgggtcga ttacaccagc ctcgcacaaa ttctcgaaac agtccttacg agcgttgtaa
    18541 ccgaagtcgc ccttgccttc cttcactttc tgaacgataa cggcaccttc cttaccagcg
    18601 ttagctacga tctggcgaag cggctcctcg atagcgcgct taacgatctc gatacctgta
    18661 gtctcgtcct cgttgtcgcc cttcatacct tccaatgcat cgatagcacg gatataggca
    18721 acaccaccac cgggcaccgt accttcttcg atagcggcac gagttgcgtg taatgcgtca
    18781 tccacacggt ctttcttctc tttcatctca acctcagaag gagcacctac gtaaagaaca
    18841 gctacaccgc cggccatctt agccaaacgc tcttgcaatt tctctttatc ataatcagat
    18901 gtcgtattct ccatctggat cttgatctgg ccgatacgag cttggatagc ctccttgtca
    18961 ccagcaccat ttacaatggt agtggtatct ttgtctaccg tgatcttctc agcggtacct
    19021 agcatatcca ttgtagcacc ttccaatttc aaacctttct cctcagagat aaccgtaccg
    19081 cctgtcaata cagcgatatc ttccaacata gccttacgac ggtcgccgaa gcccggagcc
    19141 ttaacagcgc agatcttcaa ggaaccacgc agacgattca ctaccaatgt agccaaagcc
    19201 tcgctgtcga tatcctcagc gatgatcaaa agaggacgtc cgctctgtac ggtcggctca
    19261 aggataggaa gaaggtcttt taatacggag atcttcttgt catagatcaa gatatacgga
    19321 ttctccatct ggcactccat cttctctgta tccgttacga agtacggaga gatataaccg
    19381 cggtcgaact gcataccctc aactacgtca actgtagttt cagtaccttt agcttcctca
    19441 accgtgataa caccttcagt cttcacacgt tgcatagcct ccgcgatcaa cttaccgata
    19501 gcctcgtcac catttgcgga gatcttcgct acatgctcga tcttctcgaa cttatcacct
    19561 acagcctcag cttggttagc gatgctctct acaaccttag cgacagcctt gtcgatacca
    19621 cgtttcaaat ccatcgggtt cgctccggca gtaacgttct ttaaaccgac accaatgata
    19681 gactgagcca aaaccgtagc tgtagtcgta ccgtcaccgg cgttatcgtt tgtcttggaa
    19741 gccacttcct taactaattg agcacccatg ttctcgaacg ggcaagtcaa ctcaacttct
    19801 ttagcaaccg ttacaccatc tttcgtgatg tgaggagctc cgaatttctt ctcgataatt
    19861 acgttacgac ctttcgggcc taatgttacc ttaacagcat tagccaactc atccacacct
    19921 ttcttcaaaa ggtcgcgggc atccatatcg tatttaatct cttttgccat gattgtatct
    19981 ctttttaata ttgttgttta taaaaatgaa ttagataata gctaaaacgt ctgcttggcg
    20041 catgatcaag tatttctcac cgtctagttc gatttccgta cctgcatact taccatacaa
    20101 tacgttatca ccaaccttta caaccatctc ctcgtctttc gttccgttac ctacggctac
    20161 aatctcaccc tttaaaggtt tttcctttgc tgagtcagga ataataattc cacctaatgt
    20221 tttctcttcc gcagcggccg gcttaatcag cacgcggtct gctaatggtc taatgttcat
    20281 tttcttggta ttttaaatgt taataatatt acttttttag ttatgaactt tatgttcacg
    20341 cctaagccta tgcgaatagt gtgccaaacg aattcacccg ggttcgactg acaatatttc
    20401 ggacgaaatg gacaaatatc cgaagagata actgacaact tgtctttttg catctctcaa
    20461 aaggataatc aatcgaccag cagcgtattc atggaatatg cttttacgat cggagtatag
    20521 actcgatcgc cgatgcgaat ggaaagagaa tgatcatcac tggtctcatt ggcgataatc
    20581 aaggcgatac tgttatccgg gttacggaat gccagcagat tcgtataagc tccttccgtt
    20641 tctaatttat acgcaccggg ctggacataa tggctgacat gtttcatcac gtagtattcc
    20701 ggagtatatc gatagctctt ggtttgcgga tctacgacaa ccaatgagtt ttgctcccat
    20761 ccccaacgac tgatccctcc attttccaaa gatatattcc aatacatata ggcagaaacg
    20821 ccattatcca gaaaatgtcg catcaacccc caagaataca tggcaccctt ccaatcgttc
    20881 ttgccatctc cacattcttg ctcggtttgg taaagcttca acccgggata acgtttgtgg
    20941 attccggtga tagctccctt ccccgcccat tggaaaccga caccttttac atatttacca
    21001 ctaacaggat ctgtcaatac cgtatcaaca agcgactcat tcgcacgttc catcgtgccg
    21061 aacataattt ccactccttg aacctgcatg gccggcccga gataattacc gataaaatta
    21121 gccaaagaag ccgatgtcca acaacaactc gggaatattt gcgcagagtt gaactcgttt
    21181 tggggcatta cggcaaagat tggaattcct tgtttcttat aggcctcgat aaatttagag
    21241 aaatagaggg cataggcttt caggtaaaga gggtcttgga taaacatatc cgtaccttca
    21301 tggccgacct tatcggccgg caaaccattt cgatacttct cgtcataatt ctcacccgta
    21361 taggcagagg catagtgttt gttatatttc atccaagcgg gagggcacca cggagaagcc
    21421 cacaagcgta aatctggttg atacttttgg gcgttcttga taaaagggat caaggtttgt
    21481 tggtcattgg cgatggtaaa atgttccatc gtgaaatcac catctacctc gtcatacgaa
    21541 taccaatcac gggagaaatc atttgctcct acaggcatcc ggcaaatcgt gaagttggct
    21601 ccgactccgg ggaagaaaag ctcttccatg atttcctcac gtacacttgg ctccagctta
    21661 ctcaaggaaa gccaacctaa ttcattaaaa caggctccga aaccatcaat ttgttg
//
LOCUS       DBMDTB010000070        21662 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_820_length_21662_cov_10.535504, whole genome shotgun sequence.
ACCESSION   DBMDTB010000070 DBMDTB010000000
VERSION     DBMDTB010000070.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 21662)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 21662)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21662
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_820_length_21662_cov_10.535504"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..1298)
                     /locus_tag="ACZPB4_11555"
     CDS             complement(<1..1298)
                     /locus_tag="ACZPB4_11555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RagB/SusD family nutrient uptake outer membrane
                     protein"
                     /protein_id="HIR1098882.1"
                     /translation="MKRFNIIITLSATLGLFSCELDKMPMDQVSDAVFWQKPADFELA
                     ANDFYFGLQEVSQYIDMNSDIAFGSGTNDVSDGSYLAPVNSDDWDNPWKFVQSTSYLL
                     KKAEESGLSDEEIGRWKAEAHFFRAYNYWKLVKTYGGVPKIDIPLNTSSEELYTPRSS
                     QQEIIDFIIEDLDKAIPLLPKQSGLTAEELGRTTQEAALALKARAALFEGTWQKYHGM
                     ADAGKYLDLAIQAAQAIVDSKEYELYREKGELSYKYLHILEGDDSKEVLLARRYYKLR
                     ATHNWTRELLLGAMVPTKNLADVYLCTDGLPIDKSKLFKGFQTQTSEFENRDSRMAQT
                     FVVPGSEIFSEGGGWATVEPGFIGNNSTRTGYMIRKFMDETLDAVQFIGEYDFKEFRY
                     GEVLLILAEALYEKNGQITDEQLDLTINDLRNRANMPRLT"
     gene            complement(1326..4733)
                     /locus_tag="ACZPB4_11560"
     CDS             complement(1326..4733)
                     /locus_tag="ACZPB4_11560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HIR1098883.1"
                     /translation="MNFPTITRNNWMCCSIILVFLALGSPEPLQAQENQKERITIQVK
                     NQPIQKVFDDLSKQTGLKFFYGEAIANRNVQVNLKFKNAPVNSVLNEITRQANLYFKR
                     ENNTIAVSLGNAGNASVPVTQDRKVTGIITDERGEPIIGANVVVKGTSNGTVTDLNGQ
                     YSIEANGKSILLISYIGYLSEEVAVGNNKTLNIQLKEDTQKLDEVVVIGYGTQKRSNL
                     SGAISKISSEVIDSKPVTNVLSALQGEIPGMVVQRTSGQPGNEEFDLNVRGASSTNGG
                     NTPLVLVDGIPGDMNMINPQDIEAISVLKDASASIYGSRAAGGVVLITTKKGKSGAPK
                     LTYNGNLAITKMTGIMKAPTNYEMAIMDNEANIHNGAAPLYTQELLDRILANDPNPID
                     HPTQPGWKLFFTNTDWMDELLTNGVQHRHNLTISGGGEKSNYYLSAGYSKQFGVVKYA
                     DDNNTKYNLRMNYDYRLAKWLKLETKVSLDNQKRTDIGSNGAWVIGEAMFDMPNFPIY
                     NANGEFFTQGGWSNAIALAKESETATFNTREMNGNFRLIADITDGLVFNAQVGLNYKN
                     KNNEDIAKAIPLYTWDGDINYYTGAGSPEQSAVDRTTEETIYQNYTAYLNYNKNFGLD
                     HHLDAMLGMAYEAEEVRMFMARRDNFITDELWELNLGGTGNMKNDAKAEHWATSSAFA
                     RIGYSFKNKYILETNFRYDGSSRFAPGNRWRMFPGVSASWRISQEEFLKSSKVFNELK
                     LRASYGQTGNQEGIRLYDYIQLLKFRDDGWGTKLTYPFGSGSQTQAMGLDVLAGVNRT
                     WEILENINAGIDAAFLDSRLGFSFDYFVKMNNNMLIPVTYPSMLGATPPDTNSGKLRT
                     NGFELTLNWTDKIGNVEYSAQFQLSDAKNKLVEYGGSDTYELGLNKTREGYPINSYFA
                     YVYDGVVKDQADLDAYKKLEGVPSNIGIGDAKFKDLNGDGKISTYGDKEGDDGDAKYV
                     GSTTPRYTFGLNLGAKWNNFDISVFFQGVAKRTLFREGEFSMPWSDWWRYPPQFYYGQ
                     TWNEDRQDAYYPRLTHGDIRHWNYQASTMQKINAAYVRLKNIQIGYTLPKSLLQKIGI
                     ERTRFYVSGQDLFEIHGVKGGWDPESDTGGFNYPFQRYYSFGIDLTF"
     gene            complement(4925..5938)
                     /locus_tag="ACZPB4_11565"
     CDS             complement(4925..5938)
                     /locus_tag="ACZPB4_11565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecR family protein"
                     /protein_id="HIR1098884.1"
                     /translation="MEEQNKYISDLLIRYVNGLYTRNDIETLRKLASSITERAELESE
                     MDRVWNEAQDLPQSDSHNHLLYKKEAQDLLDKTRKRERRISLSTFIKYAASIAIIVSI
                     GFGAKLYLNHSAKQHTSASDHLLTEISVNHGEHKQVTLPDGTVVHLNAGTVMRYPTEF
                     TSDIRLVEMEGEAFFNVMRDEGKPFIVRTRQADVKVLGTSFNVKAYQEDELMAVSVRT
                     GKVEVDMPESVMRLLPNEQIIVNNTNGEILKKNEDAQKVTAWLQGGLYFNRTPISSVI
                     HDLERMYNQEIVLDPNVVFDDYIYGEHDNKSLEAVLNAIQYSTGIRYRKEESRIVLYK
                     TSH"
     gene            6049..6591
                     /locus_tag="ACZPB4_11570"
     CDS             6049..6591
                     /locus_tag="ACZPB4_11570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma-70 factor"
                     /protein_id="HIR1098885.1"
                     /translation="MEERQIIKSLKEGDREAFSMLYKQYWEKVYHFCGLYLNNRDVAE
                     DVVQEVFIKVWESREFIREDDNFKGLLFIITRNLIFNHHRKNVNEDFYKMTVLSAMDT
                     SYDLEEEITAYNLGEYIDHLIEELPERRRVIFNLSRKEHKSYKEIAFQLNISEKTVEN
                     QISEALKFLKKNIMLLIWFI"
     gene            complement(6647..7267)
                     /locus_tag="ACZPB4_11575"
     CDS             complement(6647..7267)
                     /locus_tag="ACZPB4_11575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HIR1098886.1"
                     /translation="MGKPRSGIQVSIYNTPGNEQRGPTSCARVITRDTKRMNDICEYI
                     SECSSVTSADIKGVLEALTSYIGRELSYGYSVELEGLGHFSPSVKSKEVTDQKGNTKS
                     SASIHGVNFRCSPRLKEMVKKNAPILVKRENLPKTGIEGRKAKMLSYLERNSYINLTD
                     YAGLNNCTRYRASEDIKQFIKDNVIASVGYRTHRIYVLPEKEDGQN"
     assembly_gap    7492..7591
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <7592..8521
                     /locus_tag="ACZPB4_11580"
     CDS             <7592..8521
                     /locus_tag="ACZPB4_11580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecR family protein"
                     /protein_id="HIR1098887.1"
                     /translation="DALDEKDRQRLLCDPKVEERMRSQWDEAADRVNPVVGNCMWERI
                     IARTMATNGVRKLWVYKITAIAASILLLLGVGSVVYWSHTKEDQYIYVMASGVRCIEP
                     VSLSDGTTVKMGPNSQLIYPKSFDGKTRDVELKGQAFFDVAKDRERPFTVHTKNMDVT
                     ALGTAFEVFNYDSESKLETILLNGKVKIGLGGPNVKNRREVILNPNEMLVFDKQANTV
                     RVKTVNAEEYSGWRNGVLSFENERLSMILTRLEPWFGRKIKCPKEIAEKYRFTFKVRD
                     ESLERILFMLSNTSPIKYREKDNEYELYIKGDK"
     gene            8693..12067
                     /locus_tag="ACZPB4_11585"
     CDS             8693..12067
                     /locus_tag="ACZPB4_11585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HIR1098888.1"
                     /translation="MKKIRKVNRVMKISALLSLAFACTVSASTYGQNYKLSMNKQDCS
                     ISEVLKEIEKNSEYTFFLNDNQVNVNRKTSVKANNASLEEVLEQALKNTGYQYEIVDR
                     QIIIKSKSVSSVSHPNALFQSSPRKITGQVKDALGEPIIGANVVVKGTTNGTITDIDG
                     NFSLEVPDNAILVVSYIGYTDRTVEVGNSSKVMVSLSEDTQKLDEVVVVGYGTQKKVN
                     LTGAISSLDAETLENRPITNSTQALQGTQGVYVNQAGAQPGADGATIRIRGQGTLNDN
                     NPLILVDGIEFPLEAVNPNDIESISVLKDAASSAIYGSRAANGVVLVKTKGGKKGKFT
                     VDYNNYFGVQQATYLPNFVYDPVVFMEMRNQAQRNEGKLTVDYSDALIEEYKQGMLTD
                     PIMYPQNNWLDIMYNNAFIMEHNMRFSGGDDKYTYSVSLGYGDQNGVLRGTDSNKYTL
                     AVNTTAQVNSRLKIGANINAHYQIYNEPVAGVANLVEMTYKAQAFHPTYTADGRYADT
                     FIRTPGHNIYRHPLALADEGENKHKSLRMLANLSAEYKLPFDIVYNLNVGLNKYDYLQ
                     SRFAPDVYEYQLKTNEEKRVVYDGQNTRHAYKGDKNDLAVTVFNTLSWGKKFNDAHDV
                     KVLAGYSFESDDKTEFSAKVEGFLGNELHELNAGSSNPSVAGTSSRSVLMSYFGRVNY
                     GYKDRYLFEGNFRYDGSSRFAKGNRWGIFPSFSAGWRLSEEEFMKDIPWIYNLKLRAS
                     WGQLGNERIDLFRYVDLMNLKVIKNDGSITDYNYPLNGAMQSGAAITAYNDPNITWET
                     TTMTNVGIDASLLNGNLDFSFEFFDKRTSDILRKVTLPDQVGGLDGPIRNIGEVSNKG
                     FELNMGYRNNIGDFRYEVNGNMTFIKNKIVSLKGQTIIDGMFILEEGKPIDSYYMLHA
                     IGIFQSEEEIKNSPYQTAATKPGYLKFEDTNGDGKITEDDRQIRGGVIPKITYGFNIN
                     LGYKDWDLSAFFQGVTDVYTYGDRIGATPLWFGCGLPEQWLTDAWTPERGTSATLPIL
                     TTYEGCLNENFRTNDFWLRNASYLRLKNLQLSYNVPASFLKSGVVKRLKVFVNAQNLF
                     TFSPMKDFDPEKNLKGSNWYAYPSVRTYTAGVNVTF"
     gene            12086..13591
                     /locus_tag="ACZPB4_11590"
     CDS             12086..13591
                     /locus_tag="ACZPB4_11590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RagB/SusD family nutrient uptake outer membrane
                     protein"
                     /protein_id="HIR1098889.1"
                     /translation="MRRKIYKMICVAVACMSLTACDSWLDVDPSDQYSTETFWKTKEH
                     ASAGIMGCYNALKPWRSLHTMEFDMLTANAMPYNEANGTQAIGKGEHLSTTALIGSLW
                     KNCYVGIGRTNTFIANVGGVDMDESEKAKMVGEAKFLRAFYYLSLVDKFGGVPLIIDA
                     PNADEQAELPRNSKEEVVNQIVKDLEEATAVLPDTYASSDLGRATKGAALALKARTLL
                     YNSRWAEAAQAAKQVIESGVYQLFNDYRHFFSEDNKYNCEVIFDIEAKLPEYPTDYDQ
                     NIWRLNRPAPLKELVDTYLCIDGKTIEESPLYDPARPYENRDPRLLKSIVCIGYPYLG
                     KTITKEDVATTGFGVKKYTSYEDDVTIPLVERSAFNFILIRYAEVLLTYAEAQNEASG
                     PDQSVYDAINQLRRRPDINMPEVPKGLTKDQMREVIRRERRIELTFEGLYYSDILRWK
                     TAEKENNGMMHNYEGIEVVKRSFNPKRDYLWPIPYNQTVLNPNLEQNPNWD"
     gene            13676..15106
                     /locus_tag="ACZPB4_11595"
     CDS             13676..15106
                     /locus_tag="ACZPB4_11595"
                     /EC_number="3.1.6.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase family protein"
                     /protein_id="HIR1098890.1"
                     /translation="MKNKLMLLTAASAFSMAGIAADYTNIVLINLDDVGYGDFSFNGA
                     YGYTTPNIDKMAAEGIRFTHFLVGQPISGASRAGLLTGCYPNRIGFSGAPGPDSNYGV
                     HPEEMTIAEVLKQKGYSTAIFGKWHLGSQKEFLPLQNGFDEYYGLPYSNDMWPFHPQQ
                     GEVFNFPDLPTYDGNEIIGYNTDQTRLTTDYTTRSVNFIKKNKNKPFFLYLAHNMPHV
                     PLAVSDKFKGKSEQGLYGDVMMEIDWSVGEIFKALRELGLEDNTLVILTSDNGPWTNY
                     GNHAGSAGGLREAKATTFDGGNRVPCIMYWKGKTLPGTTCNKLASNIDLLPTFAEITQ
                     APLPPRKIDGVSILPLIEGKKDANPRESFVYYYRKNDLEAVTDGMFKLVFPHKYVTYG
                     AYEPGNDGQPGKLTNLEIMKPEMYDLRRDPGERYNVITQYPEEAAKLMKIADQKRHEL
                     GDDLTRMKGTERREPGLVQGKKRHDL"
     gene            15103..16677
                     /locus_tag="ACZPB4_11600"
     CDS             15103..16677
                     /locus_tag="ACZPB4_11600"
                     /EC_number="3.1.6.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase family protein"
                     /protein_id="HIR1098891.1"
                     /translation="MKQSIISIGMTACCLSGNGQSLFAANKPAQEERPNILFILSDDH
                     TSQSWGIYGGVLGEYARNENIRRLAAEGCVLDNCFCTNSISSPSRAAILTGAYSHVNG
                     VYTLSDSFDPEQDNIAKQMRAGGYQTALVGKWHLKTQPQGFDFYSVFHDQGEYRDPTF
                     INCTEPWPGERNFGERVRGFSTDIVTDKAIRWMKEADKDRPFMMCCHFKATHEPWDFP
                     ERMRHLYDGVVFPEPENLFDWGPETNGRTFSGQPLEELARRWDVASQDPDKWWCRYPE
                     LPFTTKGMHRSAARSAAYQKLVRDYLRCGATIDDNIGKLLKALDDMGIADNTIVVYVS
                     DQGYFLGEHGFFDKRMMYEESLRMPFVIRYPKEIPAGTRNKDMILNVDFASLLADYAG
                     VKTPNESQGHSFRDNLKGNTPKDWRKEMYYRYWTQHSNRPAHMGIRNERYKLMFFYGD
                     RLNMTGSEDKTTTPAWEFYDLQSDPRENHNAYNDPQYAKIIRQMKEEMLKLRKDVKDE
                     DTNTPKMKEIMDTYYW"
     gene            16894..17085
                     /locus_tag="ACZPB4_11605"
     CDS             16894..17085
                     /locus_tag="ACZPB4_11605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098892.1"
                     /translation="MNTNRDKAVSFGRDGGDVRRPVFLSMSQSRMLHPFQLRGSQSGI
                     SPAGCVNNDKLRLSGYLFR"
     gene            complement(17074..18165)
                     /locus_tag="ACZPB4_11610"
     CDS             complement(17074..18165)
                     /locus_tag="ACZPB4_11610"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 76 protein"
                     /protein_id="HIR1098893.1"
                     /translation="MYKHFLTSVLLVFFMLSCSKLSPFEGKMRECVQTSLSWRNDTTG
                     IWETAGWWNSANVLTATIRYGAVTKDPAIPSVIEDVFEKARHYQVGVDSTGTPRYCDN
                     FINDYYDDEGWWALAWIEASKLTGEKKYLDMAEIIFDDMTTGWSDACGGGIFWKKNPL
                     HYKNSIANNLFSLTAIRLYKATQNPAYLDWFKKNVDWYMRTGMINTNIYQIEDGTKDD
                     CTPNRNAHYTYNQGVAIAVLAEMYLQTNDKSYLELAEKIADATITTQLITDEGILREM
                     KPEIDDSNDGVQFKGIFIRHLAFLYEVTKNPAYKDFILKNAESIITKDYDPTSKSFGC
                     YWYGPFHKENSAANACALECVIEAYDLTK"
     gene            18300..19235
                     /locus_tag="ACZPB4_11615"
     CDS             18300..19235
                     /locus_tag="ACZPB4_11615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase"
                     /protein_id="HIR1098894.1"
                     /translation="MKKQILFICCAVIAYCLSACNTAPQQVPLKEKNLPKHVILIGFD
                     GLSAHCLNNGADMPTFRKMMAEGASTLENRSILPSSSACNWASMFMGAGPELHGYTEW
                     GSRTPELPSRVVNSDNRFPNIFGMYRDKAPEAEIGYIYEWEGMNYLVDTLAMSFRKHA
                     PMSAENPNGCTPVAVQYIKEKKPNLCAIIYDQPDGTGHGKGWSSPEYFAMVNHLDSCL
                     TQVMDAVREAGIMDDTVVILTADHGGIETGHGGKTMNEMQTPIVFYGKNVKKGFKIPE
                     STMVYDIAGTMAYLLDVPQPQVWIARPILSAFEDN"
     gene            19247..20167
                     /locus_tag="ACZPB4_11620"
     CDS             19247..20167
                     /locus_tag="ACZPB4_11620"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HIR1098895.1"
                     /translation="MKKVIYSFIFLFCAVLTLQAETMVVATYNLRNANGGDSTNGNGW
                     GQRYPYIAQIVQFHGFDIFGTQEGKYPQLQDLRQAMPGYDYIGVGRDDGKQAGEHSAI
                     FYRTDKFEVLEHGDFWLSEITDRPNKGWDAVLPRICTWGEFRDKQTGFTFLFFNLHMD
                     HVGVQARAESAKLILKKIKEFPKRLPAILTGDFNVDQTSESYKLLDGSGIMRDSYEIA
                     DFRYAPNGTFNGFHPDRKNDSRIDHLFLTKEFEVKKYGILTDTYRSEVKESAQKEQNG
                     NFPKEVSLSKYEARTPSDHFPVMIVVEVKD"
     gene            20274..>21662
                     /locus_tag="ACZPB4_11625"
     CDS             20274..>21662
                     /locus_tag="ACZPB4_11625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylase"
                     /protein_id="HIR1098896.1"
                     /translation="MIRKLLIRDLTLRDGQQSAFATRMSQAQIDRVLPYYKDAGFYAM
                     EVWGGAVPDSVMRYLGENPWDRLEIIKAEIGNSSKLSALSRGRNLFGYNPYPDEIIEG
                     FCRNSIRSGIDIMRIFDALNDVDNVKSTIRYVKKFGGKADCAICYTIDPHHSPVERIK
                     AALHGRPLHKPVFTNEYFLNKALQLESLGADMITLKDMSGLIPPARTAELVRLFKKSL
                     KVPVDFHTHCTPGYGLASVVSAIINGVDIVDTNIWNFAGGPAAPAVELVYIFCKKLGI
                     ELDLDMDAIAKINKELLTIRKELSSFDTAKKFPRPFNPVEDSFPAEIDRFFNDAIEAA
                     RKDKEDDLLLYCRAIEEYFDFPEPNELVKKAQIPGGMYTNMVAQLKQLGQIDLLEKAM
                     SLIPQVRMDAGLPPLVTPTSQIIGAQAVSCALDELKGRPMYSNPSNQFIALVKGEYGK
                     TPIPVDPAFRLKI"
BASE COUNT         5561 a         4514 c         5413 g         6074 t
ORIGIN      
        1 ttggtcaagc gaggcatatt cgcccggttt cgcaggtcat taatggtcag gtctaattgc
       61 tcgtccgtga tctgtccgtt cttctcgtat aaagcctcgg ccaagattaa taggacctct
      121 ccgtaacgga attccttgaa atcgtattcc ccaatgaatt gtacggcatc aagcgtttca
      181 tccataaact tgcggatcat gtatccggtc cgggtagaat tgttaccgat gaatcccggc
      241 tctacggttg cccatccgcc cccttccgag aatatctcgc taccgggtac gacaaacgtt
      301 tgcgccatcc gggaatcccg gttctcaaat tcgcttgtct gggtttggaa tcctttgaac
      361 aacttggatt tatcgatagg taaaccatcg gtacaaaggt atacgtccgc aaggttcttt
      421 gtcggtacca tggcacctaa taatagttcc cgggtccagt tatgagtcgc tctcaatttg
      481 taataccgtc ttgccaacaa gacttccttg ctgtcgtcgc cttctaggat atgaagatat
      541 ttgtaactga gttctccttt ctcgcgatat agttcatact ccttggaatc gacaatggct
      601 tgggccgctt ggatagctag gtcgaggtat ttgcctgcgt ccgccatccc gtggtatttt
      661 tgccaagttc cttcgaacaa ggccgcacgg gccttgagag ctaatgccgc ctcttgcgtg
      721 gtacgtccta attcctcagc ggtcagtccg ctttgcttcg gaaggagagg aatggcctta
      781 tccaagtcct cgataataaa atcgatgatc tcctgttggc tggaacgagg tgtgtaaagt
      841 tcctccgagg aggtatttaa cgggatgtct atcttgggta ctcctccata agttttcacc
      901 aatttccaat agttgtaggc acggaagaaa tgcgcttctg ctttccaacg tccgatctct
      961 tcgtccgaca aaccggattc ctccgctttc ttaagcaaat aagaggtaga ttggacaaat
     1021 ttccatgggt tgtcccaatc atccgagttg accggggcca gataggaacc gtcgctgaca
     1081 tcgttcgtgc cggaaccaaa ggcgatatcc gagttcatgt ctatatattg ggagacctct
     1141 tggagcccaa aatagaaatc gttggcggcc aattcaaagt cggccggctt ttgccagaat
     1201 acagcgtccg acacttgatc cattggcatt ttatccagct cacaactgaa tagtcctaag
     1261 gtggcggata acgtgataat tatattgaat cgtttcataa tattcgtttt attaaataga
     1321 aaaccttaga aagtcaagtc gataccaaat gagtagtaac gttggaacgg atagttgaaa
     1381 cctccggtgt cagactctgg gtcccaaccg ccttttaccc cgtgtatctc gaataagtct
     1441 tgtccgctta cataaaaacg ggtccgctcg ataccgatct tctgcaataa gcttttcggc
     1501 agggtatatc cgatctggat gttctttagg cgtacgtaag cggcgttgat cttttgcatc
     1561 gtagacgctt ggtagttcca atgcctgata tcgccgtggg tcagacgagg ataatatgcg
     1621 tcttgacgat cctcattcca ggtttgcccg taatagaact gaggcggata tctccaccag
     1681 tcgctccaag gcatggagaa ctcaccttca cggaacaagg tgcgtttagc gactccttgg
     1741 aagaatacgc tgatatcaaa gttgttccac ttggcaccca agtttaatcc gaatgtatat
     1801 cggggagtgg ttgagccgac atacttagcg tcgccgtcgt ccccttcctt atcaccgtaa
     1861 gtggagattt tcccatcgcc gttcagatcc ttgaatttgg catcgccgat accgatatta
     1921 gagggtacgc cttccagctt cttgtaagcg tccagatccg cttggtcctt gactacgcca
     1981 tcatatacat aggcgaaata ggagttgatg ggatatcctt ctctcgtctt gttcaagcct
     2041 agctcataag tgtccgagcc tccgtattcc acgagcttgt tcttagcgtc gctcaattgg
     2101 aattgtgcgg aatattcgac attaccgatt ttgtccgtcc agtttaaggt aagctcgaag
     2161 ccattcgtac gcaatttgcc cgagttcgta tccgggggag ttgcccctag catactggga
     2221 taagttacgg ggatcaacat attattgttc atcttcacga agtagtcgaa agagaatcct
     2281 aagcgggagt ctaagaaagc ggcatcaata cctgcgttga tattctccaa gatctcccat
     2341 gtgcgattta cgccggctaa gacatccagc cccatcgctt gtgtttgtga accgctgccg
     2401 aaaggatagg tcaatttagt tccccaaccg tcgtccctga attttagcaa ctggatataa
     2461 tcgtatagac gaataccttc ttgattacct gtttgtccgt aagaagctct tagtttcaat
     2521 tcgttgaata ccttagagct ctttaggaat tcctcttgag agatacgcca gctagcggat
     2581 acgccgggga acattctcca acggttaccc ggggcgaagc gggaggaacc atcgtagcgg
     2641 aagtttgtct ccaagatata cttattcttg aagctgtatc cgatacgggc gaaagccgag
     2701 cttgtcgccc aatgttcagc tttggcgtcg ttcttcatat ttccggtgcc accaaggttg
     2761 agttcccata attcgtctgt gatgaaatta tctcggcgtg ccatgaacat acggacctct
     2821 tctgcctcat aagccatacc taacatggca tctaaatgat gatccagtcc gaagttctta
     2881 ttataattca agtaagccgt ataattttga tagatggttt cctcggtcgt acgatctaca
     2941 gcggattgtt cgggactacc tgctcccgta taataattga tgtcaccgtc ccatgtatag
     3001 agcgggatgg ctttcgctat atcctcgtta ttcttgtttt tgtagtttaa gcccacttga
     3061 gcgttaaaca cgagtccgtc cgtgatatcg gcgatcaatc taaagttacc gttcatctcc
     3121 cgggtattga acgtggcggt ctcgctttcc ttggccagcg ctatcgcgtt gctccagcct
     3181 ccttgcgtga agaactctcc gttggcgtta tagatcggga agttcggcat atcaaacatc
     3241 gcctcgccga tcacccaagc gccattactt cctatgtccg tacgtttctg gttatccaaa
     3301 gatacctttg tctctaattt tagccacttt gccaatcgat aatcataatt catacgcaga
     3361 ttgtatttgg tattattatc gtctgcatat tttaccacgc caaattgttt gctgtagccg
     3421 gcggataggt aatagttaga cttctcgcct ccaccggaga ttgttaggtt atggcgatgt
     3481 tgtacgccat tggtcagcaa ctcgtccatc cagtccgtgt tcgtgaaaaa gagcttccag
     3541 ccgggttggg tgggatggtc gatagggttc ggatcgttcg ctaagatgcg atccagaagc
     3601 tcttgggtat agagtggggc ggcaccgttg tgtatgttcg cctcgttatc cataatcgcc
     3661 atctcataat ttgtcggggc tttcatgatt ccggtcattt tcgtgatcgc caagttcccg
     3721 ttgtaagtaa gtttcggtgc tccgctcttt cctttcttag tcgtgattaa tacaacacct
     3781 ccggcggcac gggaaccata tatggaggct gaggcatctt tcaataccga tatagcctcg
     3841 atatcctgcg ggttgatcat attcatatcc ccggggattc cgtcgaccaa gactagcggg
     3901 gtattccctc cgttcgtgga ggaggcgcca cgcacgttca agtcgaattc ctcgttaccc
     3961 ggttgtccgg atgttcgctg aacgaccata ccgggaattt ctccttgcaa ggcggacagg
     4021 acatttgtaa ccggcttaga gtcgattacc tcggaggata ttttcgagat cgctccggaa
     4081 agattgcttc gtttctgtgt tccgtaaccg atcacgacta cctcatcaag cttctgggtg
     4141 tcttccttta gctggatatt gagggttttg ttgttgccta cggccacttc ttccgataaa
     4201 tagccgatgt aggatatgag taggatcgat ttaccgttcg cctcgatgct gtactgaccg
     4261 ttcaggtcgg taactgtacc atttgacgta ccttttacca cgacattcgc tccgatgatc
     4321 ggttcgcccc gttcatctgt aatgataccg gtcacttttc ggtcttgcgt caccggaacg
     4381 gaggcgttgc ccgcgtttcc gagactgacg gctatcgtgt tattctcccg cttaaaataa
     4441 agattggctt gccgggtgat ctcgttcaat acgctgttga cgggagcgtt tttgaacttt
     4501 aggttaacct gtacgttccg gttcgctatg gcttctccat agaaaaattt taatcctgtc
     4561 tgcttcgaca aatcatcaaa gactttctgt atgggttggt ttttgacttg aattgttatt
     4621 ctttctttct gattttcttg cgcttgcaga ggttcagggg agcctaacgc taaaaaaact
     4681 aaaataatag aacaacacat ccaattattc ctagtaatag ttggaaagtt cataattttg
     4741 tatgtttaaa ggttgttttt atacactttt aaaaacagtc cgatttatgt aatctccaag
     4801 gggggccaat ccaagggtgt acatatcggg aaagataaag ggagatcgaa ggtcagaggt
     4861 cggtttccct tttttatgtg gctaagctta tgtcgtatct ttcatgggca aatcgatttt
     4921 aaggttaatg actcgtttta tataacacga tccggctttc ttctttccgg tatcggatgc
     4981 cggttgaata ttgaattgcg ttcagtacgg cttccagact tttattgtcg tgctcgccat
     5041 agatgtaatc gtcgaatacg acattcggat cgagtacgat ctcttgatta tacatccgct
     5101 ccaaatcgtg tataacgcta ctgataggtg tccggttgaa ataaaggccg ccttgcagcc
     5161 aagccgttac tttttgggcg tcctcgttct ttttaagaat ctctccattt gtgttattca
     5221 cgattatctg ctcgttcggt aataggcgca ttacgctttc gggcatatcc acctcaactt
     5281 ttccggtccg aacgctgacg gccatcaact catcctcttg ataggctttt acgttgaaag
     5341 aggttccgag tacttttacg tcggcttgcc gggtacggac gatgaagggc ttgccctcgt
     5401 ctctcatgac attgaaaaaa gcttctcctt ccatttctac caaacggatg tcagaggtaa
     5461 attccgttgg gtatcgcatg acggtaccgg cgtttagatg aacgaccgtg ccatcgggaa
     5521 gggtgacttg cttatgttcg ccatgattga cgcttatttc cgttaggaga tggtcgctgg
     5581 cagatgtatg ctgcttcgct gaatgattta ggtatagttt cgctccgaat ccgatggaaa
     5641 cgataatcgc tatgctcgcc gcatacttga tgaaagtgga tagggagatt cttctttctc
     5701 ttttacgtgt cttatccaac aggtcttgcg cctccttctt ataaagcaga tgattatggg
     5761 aatcggattg aggtaagtct tgcgcctcgt tccagacccg gtccatttcg ctttctaatt
     5821 ctgctcgctc ggttatggat gaggctaact tccgcaaggt ctctatgtcg ttccgtgtat
     5881 agagtccatt tacatatcgg attaataaat cgcttatata tttgttttgt tcttccatta
     5941 tttctcgtgc tatattaata gtacaaagaa gtccgggaga actgggatat cattaacttt
     6001 tattagtata tgattttatt atcttcgcga aacgatatgt gatgctaaat ggaagagaga
     6061 caaattataa agtcgttgaa agaaggagat agggaggctt tttcgatgtt gtataaacaa
     6121 tattgggaaa aggtttatca tttctgtggg ctttatttga ataatcggga tgtagccgag
     6181 gatgtggtac aagaggtgtt tatcaaggtc tgggagtcga gggaattcat ccgggaggat
     6241 gataacttca aggggcttct gtttatcatc acccgcaact tgatctttaa tcatcaccgg
     6301 aagaacgtga acgaggactt ttataaaatg acggtcttgt ccgctatgga tacctcttac
     6361 gatttagagg aagagatcac cgcctataac ttgggggagt atatcgatca tttgatagag
     6421 gaattgccgg aaagacgccg ggttatcttt aatctaagcc ggaaggagca taaaagctat
     6481 aaagagatag ccttccaact caatatttcc gagaagaccg ttgagaacca aatcagcgaa
     6541 gccttgaagt tcttgaagaa aaatatcatg ttacttatct ggtttatcta gcgctttcct
     6601 aggtcacgta tttgtagagt ccggaagtgc cactgcgtct taagttttag ttttgcccgt
     6661 cttctttttc aggcagcaca taaatccggt gtgttcgata tcctacgctg gctattacgt
     6721 tatccttgat aaattgcttg atatcctcgc tcgcacggta gcgggtacaa ttgttcaagc
     6781 cggcgtaatc ggtgagattt atatatgagt ttctttctag ataagataac atcttagcct
     6841 tccttccctc gattcccgtt ttgggcagat tttcccgttt aaccaagatg ggggcgttct
     6901 tttttaccat ctccttcagt cggggagagc agcggaagtt aacgccgtgt atgctagcgc
     6961 ttgatttagt atttcctttc tggtccgtta cttctttgct ttttaccgat ggcgagaaat
     7021 gtcccaatcc ttccagttcc acgctgtacc cataggataa ttccctgccg atataggaag
     7081 taagcgcctc caatacacct tttatgtcgg cggaggtgac ggatgagcat tcggaaatat
     7141 actcacaaat atcgttcatg cgtttggtat ctctggtgat gactcgtgcg caggatgttg
     7201 gcccgcgttg ttcattgccc ggtgtattat aaatactgac ttggatgcca cttcttggtt
     7261 ttcccatgat tttctcgtta tttaaatgga taatgtatag gatgcctcgg agatttaacg
     7321 tttatctctt tggcgtttct atttgatgaa atcggttgcc gacgccctcg gcaatgctgc
     7381 tgacgctgtc ggaaatattg ctgacggcgt cggaaatact gccgacaccg tcggcaacca
     7441 atttcattga atacaaagga cggaaatata aggatggaaa gcaaggaaga tnnnnnnnnn
     7501 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7561 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn ngatgctctg gatgagaaag atcggcaacg
     7621 tttgctgtgt gacccaaaag tggaagagcg tatgcgttcc caatgggacg aggctgcgga
     7681 tcgcgtgaat cccgtggtgg ggaattgcat gtgggaacga atcatagccc ggacaatggc
     7741 gacaaacggt gtccgtaaac tctgggtcta taagattacg gcgatagccg cctccatatt
     7801 gctactttta ggtgtaggaa gcgtagttta ttggtctcat acgaaagaag atcaatatat
     7861 atatgtaatg gcctccggtg tccgttgcat agagccggtt tccttatcgg acggtacgac
     7921 cgtgaaaatg gggccgaata gccagttgat ttacccaaag agtttcgatg gcaagacccg
     7981 tgatgtggaa ttaaaagggc aagccttctt cgacgtagcg aaagatcggg aaagaccatt
     8041 taccgtgcat accaagaaca tggatgtaac ggccttgggc acggccttcg aggtttttaa
     8101 ttatgattcc gagagcaagt tggagacgat cctgctaaac ggtaaggtga agattggctt
     8161 gggaggtccc aatgtgaaga acaggcgtga ggtgatattg aatccgaacg agatgttggt
     8221 tttcgacaaa caagcgaata ccgttagagt taagacggtt aatgccgagg agtattcggg
     8281 ttggcgtaat ggtgtcctca gttttgagaa cgaacgcttg agcatgatcc ttacccgtct
     8341 ggagccttgg ttcgggcgga agataaaatg cccgaaggag atagcggaga aatatcggtt
     8401 tacgtttaag gtacgggatg aatccttgga gcgaatcctg tttatgctga gcaatacgtc
     8461 gcccattaaa tacagagaga aagacaatga atatgaacta tatataaagg gagataaatg
     8521 agtgtctaac gttaaattct aagagatatg cttgttaaca gttcttgagt ctaataaaaa
     8581 acaggaggga aaactaggtt tctcctcctg agcaaatgtt cttgacggca ggcgttagga
     8641 gttgagaggc cgacacacct gctaatttat tcatcagaaa cattacaaag ttatgaaaaa
     8701 aatcagaaaa gtaaaccgag tcatgaagat aagtgcgttg ttatccttgg ctttcgcatg
     8761 cactgtatcc gcttctacct atggacagaa ttataagctt tccatgaata aacaggattg
     8821 cagtatatcg gaagtgctaa aagaaataga gaaaaatagt gagtacacgt tcttcttgaa
     8881 tgataatcaa gtaaatgtaa ataggaaaac gagtgtaaaa gcaaataatg cctcgttaga
     8941 ggaggtctta gagcaagcct tgaaaaatac gggataccaa tatgagattg tagaccggca
     9001 gattataatt aagtcaaaga gtgtttcaag tgtctcacat ccgaatgcct tattccagtc
     9061 ttcgccacga aagattaccg ggcaagtaaa agatgccttg ggagaaccca ttatcggggc
     9121 gaatgttgtc gttaaaggaa ctacgaacgg aacgattacg gatatcgatg gaaacttcag
     9181 tctggaagta ccggacaatg cgattttggt agtttcttat atcggttata cggatcgtac
     9241 ggtcgaggtt ggtaattctt cgaaagtaat ggttagcctg tccgaggata cccagaagtt
     9301 ggatgaggtt gtggtcgtag gttacggaac gcagaagaaa gtgaatttaa caggagcgat
     9361 ctcctctttg gatgcggaga cgttggagaa tcgtccgatc accaactcga cccaagcgtt
     9421 gcaaggtacg caaggtgttt acgtaaatca agcgggtgct cagccgggag cggacggggc
     9481 gacgattcgt attcgtggtc agggaacctt gaacgataat aacccgttga ttttggtgga
     9541 tggtatcgag ttcccgttgg aagcggtaaa tccgaatgat attgagagta tttccgtatt
     9601 gaaagatgcg gcttcttccg ctatctacgg ttctcgtgcg gcgaatggcg ttgtcttggt
     9661 aaagacaaag gggggaaaga aaggtaagtt taccgtcgat tataataact atttcggcgt
     9721 gcagcaggct acctatctgc ctaacttcgt atatgatccg gtcgtgttta tggaaatgag
     9781 aaaccaagcg caacggaacg aaggtaaact aacggtggat tattctgatg cgttaatcga
     9841 ggagtacaaa caaggtatgt taacagaccc gattatgtat ccgcagaata attggttgga
     9901 tattatgtat aataatgcct ttattatgga gcataacatg cgtttctccg gaggtgatga
     9961 taaatatacg tattccgtat ctttaggcta tggtgatcaa aatggagtat tgcgtggaac
    10021 ggattccaat aaatatacct tagctgtgaa tacgactgct caggtaaata gccgtttgaa
    10081 gatcggcgct aatatcaatg cgcattatca gatctataat gagccggtag cgggtgtggc
    10141 aaacttagtg gagatgactt ataaagcgca ggctttccac ccgacttata cggccgatgg
    10201 tcgctatgcg gatactttta tccgtactcc tgggcataat atctatcgcc atccgttggc
    10261 gttggccgat gagggcgaga acaagcataa gtccttgcgt atgttggcga atttgtctgc
    10321 ggaatataag cttccgtttg atatcgttta taacttgaat gtcggtttaa acaaatatga
    10381 ttatctgcaa tctcgttttg cgcctgatgt atacgaatat cagttgaaga ccaatgagga
    10441 gaaacgagtg gtttatgacg gtcagaatac acgccatgcc tataaaggtg ataagaatga
    10501 cttggcagtt acagtattca atactttatc ttggggcaag aagttcaatg atgcccatga
    10561 cgtaaaagta ttggctggct atagttttga gagcgatgat aagactgagt tttccgctaa
    10621 ggtagaaggt ttcttaggga acgagttgca cgaattaaac gcaggttcta gtaatccgag
    10681 tgtagcgggt acttcctcga gatcagtctt gatgtcttac tttggtaggg tgaattatgg
    10741 ttataaggac cgttatttat ttgagggtaa ctttcgttat gatggttcgt ctcgttttgc
    10801 caaaggaaat cgttggggta ttttcccatc attctctgcc ggatggcgtt tgagcgagga
    10861 agagtttatg aaagatattc cttggatcta caatctgaaa ttgagagctt cttggggaca
    10921 attgggtaac gagcgtatcg atttgttccg ttacgtggac ctaatgaact tgaaggtgat
    10981 aaaaaatgat ggttcaatta cggattataa ctacccgttg aatggagcga tgcaatccgg
    11041 agcagctatt accgcctata acgatccgaa catcacatgg gagacaacga ccatgacgaa
    11101 tgtcggtatt gacgctagct tgttaaacgg aaacttagat ttctctttcg agttctttga
    11161 taaacgtact tccgacatct tgcgaaaggt tactttgccg gatcaagtag gtggtctgga
    11221 tggcccgatc cgtaatatcg gcgaggtgag caataaaggt ttcgagttga atatggggta
    11281 tcggaacaat atcggggact tccgttacga ggtaaatgga aatatgacct ttatcaagaa
    11341 taagatcgtt agcttgaagg ggcaaacaat cattgatgga atgtttatct tggaagaagg
    11401 aaagcctatc gattcttatt atatgcttca tgctatcggt attttccaat ctgaggagga
    11461 aatcaagaat agtccgtatc aaaccgcggc tactaaaccg ggatatctga agtttgagga
    11521 tacgaatggc gatgggaaaa ttaccgaaga tgaccgccag atacgtggtg gtgtgattcc
    11581 aaagataact tatggattca atatcaactt aggatataag gattgggatc tgagcgcatt
    11641 cttccaaggt gtaactgatg tctatacata tggagaccgc attggtgcta ctcctttatg
    11701 gtttggctgt ggtttgccgg aacaatggtt gacggatgct tggactcccg agcggggaac
    11761 cagcgctaca ttgcctatct tgactacgta tgaaggatgc ttgaacgaga atttccgtac
    11821 aaatgatttc tggttgagaa atgcctctta tttacgtttg aagaacttgc aactttctta
    11881 taacgtaccg gcctcttttt tgaaaagcgg tgtggttaag agattaaagg tctttgtcaa
    11941 tgcgcaaaac ttattcacgt tctctccgat gaaggatttt gatccggaga agaacttgaa
    12001 gggaagcaac tggtatgcct atccgtctgt acggacttat acggcaggtg ttaatgtcac
    12061 attttaaata ataaggaata ataatatgag acgtaaaata tataagatga tatgtgtcgc
    12121 tgtcgcttgt atgagtttaa ccgcttgcga tagctggttg gatgtagatc cttccgatca
    12181 atattccacg gaaacattct ggaagacaaa agagcatgcg agcgccggta taatgggatg
    12241 ttacaacgca ttgaaacctt ggcgttcatt gcatacgatg gaattcgata tgctgacagc
    12301 gaatgcgatg ccttataacg aggcgaatgg tacgcaagcg attggaaagg gtgaacattt
    12361 gtctactacg gctctaatcg gaagtttatg gaagaactgt tacgttggta ttggccgtac
    12421 gaatactttc atcgctaatg tcggaggtgt cgatatggat gagtcggaga aggcgaagat
    12481 ggtgggtgaa gccaagttct tacgagcttt ctattattta agtctggtcg ataaattcgg
    12541 aggtgtaccg ctgattatag atgctcccaa tgcggatgag caagccgaat tacctcgcaa
    12601 ttccaaggaa gaggtagtga atcagattgt caaggatttg gaggaggcca ctgccgtgct
    12661 accggacacc tatgctagct cagacttggg acgtgcgaca aaaggtgctg cgttagcgtt
    12721 aaaagcccgt actttattat ataattctcg ttgggcggag gcggcccaag ctgctaagca
    12781 ggtaatagag tctggcgttt atcaattatt caatgattat cgtcatttct ttagcgaaga
    12841 taataaatat aattgtgagg taatctttga tatagaagcg aaattgccgg agtatccaac
    12901 ggattatgat cagaatatct ggcgcttgaa tcgtccggct cccttgaagg aactggttga
    12961 tacatatctc tgtattgacg ggaagacgat agaagagtca ccgctttatg atccggctcg
    13021 tccgtatgag aacagagatc cccgtttatt gaaatcgatc gtttgcatcg gttatccgta
    13081 tttaggaaag acgatcacaa aagaagatgt ggcgactacg ggtttcggtg tgaagaaata
    13141 cacttcttat gaggatgatg taacgattcc tttagtagaa cgttcggctt tcaatttcat
    13201 tttgattcgt tatgcggaag ttctgttgac gtatgccgag gcgcagaatg aggcgagtgg
    13261 tcctgatcag tcagtttatg atgccatcaa ccaattgcgt aggcgtccgg atatcaatat
    13321 gccggaagta ccaaaaggtt tgacgaaaga tcagatgcgt gaggtaatcc gccgtgaacg
    13381 ccgtatcgag ttgacctttg aaggactcta ctattcggat atcttgcgct ggaaaaccgc
    13441 cgagaaagaa aataatggta tgatgcataa ttatgaggga atagaagtcg tgaaacgttc
    13501 ttttaatccg aaacgagatt atttatggcc gatcccttat aaccaaacag tcttgaaccc
    13561 taatttggag caaaatccga actgggatta attcttgggt aaattaaaaa ctgttatctt
    13621 tgaagtgcca aacacaggat ggcacttcaa agccaatatt tcaataaata atatcatgaa
    13681 gaataaacta atgttactga cggccgcctc agctttttca atggcaggca tagccgctga
    13741 ttacacgaat atcgtcctaa tcaatttgga tgatgtgggt tacggagatt tttcttttaa
    13801 tggagcttac ggatatacca ctccgaatat cgataagatg gcggcggaag gcattcgttt
    13861 tacgcacttt ttggtaggac agccgatcag tggagcctct cgtgccggct tgttgaccgg
    13921 ctgctatccg aatcgtatcg gtttttccgg cgctccgggg ccagattcga actacggtgt
    13981 ccatccagag gagatgacga tcgcagaggt attgaaacag aaaggatata gtaccgctat
    14041 cttcggtaaa tggcatttag gtagccaaaa ggagttcctc cccttgcaaa atggcttcga
    14101 tgaatattat gggttgccgt attctaacga tatgtggcct ttccatccgc aacaaggtga
    14161 ggtctttaat ttcccggatt tgccgactta tgacggaaat gagattatcg gttataatac
    14221 ggaccaaaca cggttgacta cggattatac cacccgttct gttaatttca tcaagaagaa
    14281 taagaataag cctttcttct tgtatctggc ccataatatg ccccatgtac cgttggccgt
    14341 ttccgataaa ttcaagggaa agagcgagca gggtttatat ggcgacgtga tgatggagat
    14401 cgactggagt gtaggtgaga tattcaaggc attgcgtgag ctgggcttgg aagataatac
    14461 gttggtgatc ttgacttccg ataatggccc ttggaccaat tacgggaatc atgccggttc
    14521 agccggtggg ttacgtgagg caaaggctac gacctttgat ggtggtaacc gggttccttg
    14581 tatcatgtac tggaaaggta agacgttacc gggcacgact tgtaataagt tagcttctaa
    14641 tatcgacctt cttcctacgt tcgccgagat cacgcaggct ccgcttcctc ctcgcaagat
    14701 tgacggagta agtatcttgc cgttgatcga gggtaaaaaa gacgccaacc cacgtgagtc
    14761 tttcgtctat tactatcgaa agaatgactt ggaggctgtt acggatggaa tgttcaaatt
    14821 ggtattcccc cataaatacg ttacttatgg ggcttatgag ccgggaaacg acggccagcc
    14881 gggtaagttg acgaatctgg agatcatgaa gccggagatg tacgacctgc gccgtgatcc
    14941 gggagagcgt tataacgtga ttacccaata tccggaggaa gccgctaaat tgatgaagat
    15001 cgcggaccag aaacgccatg agttagggga tgacttgact cgtatgaagg gtacggaacg
    15061 tagggaaccg ggtttagtac aagggaaaaa acgtcatgac ttatgaaaca atcgatcatt
    15121 agtatcggaa tgactgcctg ttgtctttcg ggaaacgggc agtctctctt tgccgccaat
    15181 aaaccggcgc aagaggaacg tcccaatatc ttgtttatcc tatcggatga tcatacttcc
    15241 caatcgtggg gtatttacgg gggcgtgttg ggggaatatg cccgcaacga gaatatccgt
    15301 cgcttggctg cggagggttg cgtattggat aattgttttt gtacgaactc gatctcttct
    15361 ccgagtcgcg cggcgatctt gaccggagcc tatagtcacg tgaacggtgt ctacacgtta
    15421 agtgattctt ttgatccgga gcaggataat atcgccaagc aaatgcgggc gggaggctat
    15481 cagaccgctt tggtcggtaa atggcatctg aaaacgcaac cgcaaggttt cgacttctat
    15541 tccgtgttcc atgaccaagg cgagtaccga gaccctactt ttataaattg tacggaacct
    15601 tggccgggtg agcgtaattt cggggagcgg gtacgaggtt tctccacgga tatcgtgaca
    15661 gataaggcga tccgttggat gaaagaggcc gataaggacc ggcctttcat gatgtgttgt
    15721 catttcaagg ctacacacga accttgggat tttccagaac ggatgaggca tttgtatgac
    15781 ggcgttgttt tcccggaacc ggagaactta tttgattggg ggccggagac gaatggacgt
    15841 actttctccg gacagccttt ggaggagttg gcccgtcgtt gggacgtggc gtcgcaagac
    15901 cctgataaat ggtggtgccg gtatccggag ttgcctttta cgacgaaggg gatgcatcga
    15961 tctgccgccc gtagcgccgc ttaccagaaa ttggtgcgcg actatctgcg ttgcggggct
    16021 acgatcgacg ataatatcgg gaagttattg aaagcgctgg acgatatggg aatcgccgat
    16081 aatacgatcg tggtgtacgt atccgaccaa ggttatttct taggagagca tggtttcttc
    16141 gataagcgta tgatgtatga ggagtctcta cgtatgcctt tcgtgatccg ttacccgaaa
    16201 gagatcccgg cggggacccg caataaggat atgatcttga acgtggattt tgcctctttg
    16261 ctggcggatt acgcaggcgt gaagaccccg aatgaatcgc agggccatag ttttcgcgat
    16321 aatctgaaag gaaatacccc aaaggattgg cgtaaggaga tgtattatcg ttattggacc
    16381 caacattcga accgtccggc ccatatgggt atccgtaatg agcggtataa actgatgttt
    16441 ttctatggcg accgtctgaa tatgactggt tcggaggata agaccacgac accagcatgg
    16501 gagttttacg accttcaatc cgatcctcgt gagaatcaca acgcttataa cgatccccaa
    16561 tacgccaaga tcattcggca aatgaaggag gagatgctga agctgcggaa agatgttaag
    16621 gatgaggaca cgaatacccc taaaatgaag gagattatgg atacctatta ttggtaaaaa
    16681 gaaaacggag ggagacgtag cgtgctgcgt cgcctatcct ttgtaataga agtccacgct
    16741 agcaaccgag agggagtgcg gtatgttata aagcatgtat ttctagaaag aagaaggaat
    16801 ttgttctttt gtgaaaaaga agtcttatgt ttgtgcacga tatgaaaaac agggtttata
    16861 tggccccgtt atcagtaaaa aaccagcctt gacatgaata caaacagaga taaggctgtc
    16921 tcttttgggc gggacggcgg agatgtccgc cgtcccgttt ttttgtcaat gagccagagc
    16981 cgtatgttac atccgttcca gctccggggg agccagagcg gaatatcgcc cgctggctgt
    17041 gtgaataacg acaagctgcg tctttccgga tacctatttc gttaaatcat aagcctctat
    17101 cacgcattcc aaagcgcaag cgtttgctgc cgagttttcc ttgtggaaag ggccgtacca
    17161 ataacaaccg aagcttttgg atgtgggatc ataatctttt gtgatgatgg attccgcatt
    17221 tttcaagatg aaatctttat aagccggatt ctttgtcact tcatacagga aggctaaatg
    17281 acggatgaag atacccttaa attggacacc gtcgttgcta tcatcgatct cgggcttcat
    17341 ttcacggaga ataccctcgt cagttatcaa ttgtgtggtg atggtagcgt cggcgatctt
    17401 ttccgctagt tccaaataag atttatcgtt ggtttggaga tacatctcgg ctaagacagc
    17461 gatggctacg ccttggttat aggtgtagtg ggcatttcgg ttgggggtac aatcgtcttt
    17521 ggtaccgtct tcgatttggt agatgttcgt attgatcatg ccggttcgca tataccaatc
    17581 tacgttcttc ttgaaccagt cgaggtatgc cggattctgg gtcgctttat ataaacggat
    17641 cgccgtaagg gagaataagt tgttggcaat cgagttcttg taatgcagtg gattcttctt
    17701 ccagaaaatg ccgcctccgc aagcgtcgct ccagccggtt gtcatatcat cgaatatgat
    17761 ctcggccata tctaggtact ttttctctcc ggtcagtttg gaggcctcga tccatgccaa
    17821 tgcccaccaa ccctcgtcat cgtaataatc gttgatgaag ttgtcgcaat aacggggagt
    17881 accggttgag tctacgccta cttggtaatg acgggctttc tcgaatacat cctctatgac
    17941 agaagggatg gccggatctt tggttacggc accgtagcga atggtggcgg ttaatacgtt
    18001 cgccgagttc caccagcctg ctgtttccca gataccggtc gtgtcgtttc tccagcttag
    18061 ggaggtttgt acgcattctc gcatctttcc ttcaaaaggg gaaagtttgc tacaggatag
    18121 catgaaaaat acaagcaata cgcttgtcag gaaatgtttg tacatacgta tttattaaaa
    18181 taagattaga ttaagctaca aagataaatg atctttttga actttattta aactttgtac
    18241 ctttgtctga cggaatctaa gatacttcaa tattaatcat aaaagaaaaa cacggtaaga
    18301 tgaaaaagca aatcttattt atttgttgtg cggtaatcgc atactgcctg agcgcctgta
    18361 atacggcacc tcagcaagtg cctttgaaag agaagaatct gccaaagcat gtaatcttga
    18421 ttggtttcga cggcttgagc gcccattgct tgaataatgg ggcggatatg cctactttcc
    18481 gtaagatgat ggcggaaggt gcttccacgt tagagaatcg ttcgatcctg ccttcgtcga
    18541 gtgcttgtaa ttgggcttcc atgtttatgg gagcaggacc ggagttgcac ggatatacgg
    18601 agtggggatc tcgtacgccg gagcttcctt cccgtgtcgt gaatagcgac aaccgtttcc
    18661 cgaatatctt cggcatgtac cgggataagg ctcccgaggc tgagattggc tatatctatg
    18721 agtgggaagg catgaattat ctggtggata ccttggccat gagcttccgt aagcatgccc
    18781 cgatgtcggc tgagaacccg aacggatgta ccccggtagc cgttcagtat atcaaggaga
    18841 agaagccgaa cctttgcgcg attatatacg atcagccgga tggtaccgga catggcaagg
    18901 gatggagttc cccggagtat ttcgccatgg tgaatcattt ggacagttgc ttgacgcaag
    18961 tgatggacgc cgttcgtgag gcgggtatca tggatgatac ggtggttata ctgacggccg
    19021 accacggcgg tatcgagacc ggtcacggtg gcaagacgat gaacgagatg caaaccccga
    19081 tcgttttcta tggaaagaac gtaaagaaag gcttcaagat cccggagagc acgatggtat
    19141 atgatatcgc cggtacgatg gcttacctat tggacgtacc gcagccgcag gtgtggatcg
    19201 cccgtccgat attatcagct ttcgaggata attaaaaaca tagatcatga agaaagttat
    19261 ttattctttt atttttcttt tttgcgccgt attaacctta caggcggaga caatggtggt
    19321 tgccacctat aatttgcgta acgccaacgg cggcgattcc acgaacggta acggttgggg
    19381 acaacgttat ccttacatcg cccagatcgt acagtttcac gggttcgata tctttggaac
    19441 ccaagagggc aaatatccgc aattgcagga cttgaggcaa gccatgcccg gatacgatta
    19501 tatcggcgtg ggacgtgacg atggtaagca ggcgggagag cattcggcta tcttttaccg
    19561 cacggacaag ttcgaggtct tggagcatgg cgatttctgg ctatccgaga tcaccgaccg
    19621 tccgaataaa ggctgggacg ccgttctgcc ccgtatctgt acgtggggcg agtttcggga
    19681 caaacagacc ggcttcactt tcttgttctt caaccttcat atggaccatg tcggcgtaca
    19741 agcccgtgcc gagagcgcta agttgatctt gaagaagatc aaggaattcc cgaagagact
    19801 tcccgctatc ctgaccggag atttcaatgt tgatcaaaca agtgagtcat ataagttgtt
    19861 agatggttct ggtatcatgc gtgactctta tgagatcgca gatttccgct atgccccgaa
    19921 tggtaccttc aacggtttcc atccggaccg caagaacgat agccgtatcg accatctttt
    19981 cttgaccaag gagtttgagg tgaagaagta tggaatctta acggatacct atcgctccga
    20041 ggtgaaagaa agcgcccaga aggagcaaaa cggcaatttc ccgaaagagg tgtcattgag
    20101 caaatacgag gcccgcactc cttccgacca ctttcccgta atgatcgttg tggaagtaaa
    20161 agactgaggt tttagaaaaa ttggttatta ttaaccccgt aatctttatc aaatttgttt
    20221 agatcctgtt atataatcag aatattgact aaaacgatct aaacaaattt ggtatgatac
    20281 gtaaattatt gattcgtgat ttgactcttc gcgatggtca gcaatcggca ttcgctacaa
    20341 gaatgtctca agcgcaaata gaccgtgtac ttccttacta caaagacgca ggcttttacg
    20401 ccatggaagt atggggtggg gcggttcccg attccgtgat gcgttattta ggtgagaatc
    20461 cgtgggatcg tttagagatc atcaaagcgg aaataggtaa ttcctcaaag ctatccgctc
    20521 tttcccgtgg gcgtaattta ttcggttata atccttatcc cgacgagatt atagaaggct
    20581 tttgccggaa ctcgattcgt tccggtatcg atatcatgcg tattttcgat gctttgaacg
    20641 acgtggataa cgtgaaatcc acgatccgtt atgtgaagaa attcggggga aaggccgact
    20701 gtgccatctg ttatacgata gatcctcacc attccccggt agaacgtata aaagccgcct
    20761 tgcatggacg gcccttgcat aagcctgttt ttacgaatga gtatttctta aacaaggccc
    20821 ttcaactgga gtcgctgggc gcagatatga tcaccctgaa ggatatgagt ggtttgatac
    20881 ctccggctcg tacggcggaa ttggtgcgat tgttcaagaa gagcttgaaa gtaccggtgg
    20941 atttccatac gcattgtacg cccggttacg gattggcgtc ggtcgtatcc gccattatca
    21001 atggggtgga tatcgttgat acgaatatat ggaacttcgc cggaggacca gccgctcccg
    21061 cagtagaact ggtctatatc ttctgcaaga aattgggtat cgagctggat cttgatatgg
    21121 atgcgatcgc taagatcaac aaggaattat tgacgatccg caaggaactt tcctcgttcg
    21181 ataccgcgaa gaaattccca aggcccttta atcccgtaga agatagtttc cccgccgaga
    21241 tcgaccgctt cttcaacgat gccatcgagg ccgctcggaa agataaggag gacgatttgc
    21301 tgctttattg ccgtgcgatc gaggagtatt ttgatttccc cgagccgaac gagttggtga
    21361 aaaaagcgca gatcccggga ggtatgtaca caaatatggt tgcccagttg aagcagttgg
    21421 ggcagatcga cttgttggag aaggcgatgt cactcattcc gcaagtacgg atggatgccg
    21481 gcttgcctcc gttggtgacg cctacgagcc agattatcgg ggcgcaagcg gtttcctgtg
    21541 cgctggatga gctgaaaggc cgcccgatgt atagtaatcc ttccaaccag tttatcgcct
    21601 tggtaaaagg agagtatggc aagacgccga ttccggtaga tccggcgttt cggttgaaaa
    21661 tc
//
LOCUS       DBMDTB010000071        21541 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_824_length_21541_cov_11.558489, whole genome shotgun sequence.
ACCESSION   DBMDTB010000071 DBMDTB010000000
VERSION     DBMDTB010000071.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 21541)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 21541)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21541
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_824_length_21541_cov_11.558489"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..1404
                     /locus_tag="ACZPB4_11630"
     CDS             <1..1404
                     /locus_tag="ACZPB4_11630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HIR1098897.1"
                     /translation="ALANVLITDPELIILDEPTNHLDLEMTEWLEDYLSRANISILMV
                     THDRYFLDRVCSEIIEIDNKQIYSYKGNYSYYLEKRQERVEAMNADVERAKNLLRTEL
                     DWMRRQPQARGTKAKYRIDAFYELEKKAKQQRDTGKVNLDVKASYIGSKIFEAVNVSK
                     RFGDLKITEDFNYIFARYEKMGIVGNNGTGKSTFIKMLMGEVAPDSGHFDVGETVRFG
                     YYSQDGLKFDEQMKVIDVVQAIAEYVDLGNGQKMGVSQFLNYFLFTPEKQHSYVYKLS
                     GGEKRRLYLCTVLMRSPNFLVLDEPTNDLDIVTLNVLEEYLRNFKGCAIVVSHDRYFM
                     DKVVDHLLVFRGNADIKDFPGNYTQYRDWKDVQDQLEKEAEAALQARQNPAPEKPSRP
                     VNEQKKKLTFKERKEFEALEEEIPALEAEKAELETAMSSGTLSTDELMAKSQRITQVM
                     EEIDEKTMRWLELSELA"
     gene            1418..2593
                     /locus_tag="ACZPB4_11635"
     CDS             1418..2593
                     /locus_tag="ACZPB4_11635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HIR1098898.1"
                     /translation="MSETKPVLWNRNFVQCCISYFLMNFAFYMLMPTMPVYLVEELGI
                     STSEVGMVLSSYTIGLLCVRPFSGYLVDCFSRKPLYVFAFTIFACLFAGYWFAMTVYT
                     IMAVRFIQGGFMGLTSVSGNTITIDVIPSKRRGEGMGFYGLTINLAMSLAPLVAVGLY
                     DRHGFFWIIGVALVIALVGIGSVGLIRYPKREKVPRPAFSLDRFILVKALPAALAYLL
                     VAIPYGMLLSFVVLYGKEIEVPDPGYFFIFMAIGVGTARLISGRLVDHGKIHVVSIVS
                     LVSLAISFSVFATVHTSFVFFACALAIGIGFGVSVPAFQCLFVNVAPHHMRGTATSTY
                     LTSFDFGMGIGMLSAGFIATRANLATAYGVGAVCCLLSLFVYIRLVKASYERNKLIS"
     gene            2622..3278
                     /locus_tag="ACZPB4_11640"
     CDS             2622..3278
                     /locus_tag="ACZPB4_11640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098899.1"
                     /translation="MDKINSLFTIGNVNEDNAQKIFADIATELFEHCFIKQGEAVKYK
                     FLEVEFYFWSEAHKDNKLDNEGKKEVPFVYPRNNTQPAQYLVHASGMDLCFKSDNGYG
                     GILIRSLLRIEGKEQSVVTGPWDCCYALINYMGGSENVFPKLTYGEEKDTQVELETAI
                     RHNVPVGSSMKNAPYCFYNKKYMHKSGKWGFEDAELKRYNPSTRKSVANTYSIKPWNR
                     "
     gene            3289..4182
                     /locus_tag="ACZPB4_11645"
     CDS             3289..4182
                     /locus_tag="ACZPB4_11645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004668 - protein-arginine deiminase
                     activity [Evidence IEA];
                     GO_process: GO:0009446 - putrescine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase family protein"
                     /protein_id="HIR1098900.1"
                     /translation="MVLSENQKNKVYFSNLLALNYPSIWKEICNVLSIYGYSAGRLTY
                     TKDYWCRDFMPIQVGSNEFVQFQYDPDYLTDLRKYKTNPNDTVKHITDFTPKISKSKL
                     LVDGGNIVVCNNINEETWVVMTEKVLIENPDFSKAEITSMLEKDLGARIVWLPWDTSD
                     ECGHTDGIVNFINGLSSKPSIMAYFSLYPKNIAKEMRKLLNDVFDTHELIFTHDEKNN
                     WAYVNLLRTKDFIIVPGLGTDSDNEAMGQIERLYPDYKGRIHQIIIAPIVEEYGGAFN
                     CLTWTVNTEDIDSYISIPGFV"
     gene            4301..4684
                     /locus_tag="ACZPB4_11650"
     CDS             4301..4684
                     /locus_tag="ACZPB4_11650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098901.1"
                     /translation="MKRLVMAMSALLVSVTMSFAQESSLHKEPFVVNVGQLVSYLELR
                     PSQINEVAMINDYFREKQSEGLRGSHKMRDKRMRQAVFGNLKLMKKALSTDQYRKYVA
                     LINVTNNNNRMMSGLSFPDVYLADK"
     gene            5141..5524
                     /locus_tag="ACZPB4_11655"
     CDS             5141..5524
                     /locus_tag="ACZPB4_11655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098902.1"
                     /translation="MRRLGMMVVALMMVATMSFAQKVSDSKSMSFDKLSRYLQLDANQ
                     IAEVSEINTYFENQLGQPLSAEALCNNARPEETRNALLCNLKLMKRALTKDQYRKYVA
                     LINVTRTNQEDKVSNPLLDSYLAEK"
     gene            5599..5991
                     /locus_tag="ACZPB4_11660"
     CDS             5599..5991
                     /locus_tag="ACZPB4_11660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098903.1"
                     /translation="MKRFGMAVAALLMCATMSFAQKPSLSREPFVVSTEKLANYLQLT
                     PSQLDEVANINEYFIEMQNASVKASAKLQDKKMYQAVYGNLKLMKKALSPDQYRKYVT
                     LLNITNNNNRTLGVNTFPEVYLADNASK"
     gene            6133..7032
                     /locus_tag="ACZPB4_11665"
     CDS             6133..7032
                     /locus_tag="ACZPB4_11665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HIR1098904.1"
                     /translation="MTTQKLLVPSNATLKRNVMDYSLIVVGSFLQALSYVLFLAPYKI
                     VPGGVYGISIVIHYVTKDLFPFFPDGLPMGATALCFNIPLMILAMKKIGLSSGPKTIV
                     TFLLISIFTDSLSYFLTDPLVENDAFIAAFYGGAILGLGVTCIFRAQSTSAGTDVLAR
                     VIANDSNLKVSNMIIVLDSAVVLLGLIVFKDWAVPLYSWFTIFVYGKIVEMFQTENPN
                     RAVFIVSRKTQELKTLIVDKMGMRGTFIHGKGMYQGNETEIIFTIAERKDMPRLKDEV
                     KEIDPNAFVSTMHASKDSPRPGI"
     gene            7091..8377
                     /locus_tag="ACZPB4_11670"
     CDS             7091..8377
                     /locus_tag="ACZPB4_11670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HIR1098905.1"
                     /translation="MMDRRGFLKNATLVSAACLMDFREALAWGAKDAEVGKAWKGWKK
                     GQFQIHLIYTGVSESMFLIFPDGTTMLLDCGDHNAVGRGKLAVPVLPNPDRHAGEWIS
                     RYVRRVNPQKDYVDYMMLTHYHSDHGGNNKFYARKETRDGKDYYLSGFSQAAEYLTFG
                     KAFDRCWPDYNDPLPLTQEAADAFEHMKDFYDYMLAHKKMEIEKFCLGETNQIAMKKD
                     ATAYPGFSVRNICANGRIADKEGNIRDLYAERKKSNPVKFSENGMSLGMIFTYGDFKF
                     YTAGDFSDGWELPNGKRFEIEDAIADVVEPVSVAKINHHGHKSMTDKLVAALRPRVVV
                     NNVWDQLHTLPSVMERFYNRNLYPGERIVCPTVFPAERRAEDAGQPWLDILNPSSFDA
                     GHVIVNVEEGGKDYSVTYLTANDESMTVKSVMRFKS"
     gene            8455..9654
                     /locus_tag="ACZPB4_11675"
     CDS             8455..9654
                     /locus_tag="ACZPB4_11675"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HIR1098906.1"
                     /translation="MPNISQRGVEMPASPIRKLAPLADAAKQRGVHVYHLNIGQPDLP
                     TPRAALDAIRNVDRTVLEYSPSQGYRSYREKLVGYYKKYDINLTADDIIITTGGSEAV
                     LFAFLSCLNPGDEIIVPEPAYANYMAFAISAGAVIRTVTTTIEEGFSLPKVEKFEELI
                     NERTKAILICNPNNPTGYLYTRREMNQIRDIVKKYDLYLFSDEVYREFIYTGSPYISA
                     CHLEGIEQNVVLIDSVSKRYSECGIRIGALITKNAEVRSAVMKFCQARLSPPLIGQIA
                     AEASLDASEEYARETYDEYVERRKCLIDGLNRIPGVYSPIPMGAFYTVAKLPVDDADK
                     FCAWCLEEFEYEGQTVMMAPASGFYTTPGLGKNEVRMAYVLKKEDLAKALTVLSKALE
                     AYPGRML"
     gene            9655..10899
                     /locus_tag="ACZPB4_11680"
     CDS             9655..10899
                     /locus_tag="ACZPB4_11680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1098907.1"
                     /translation="MNLELFIAKKIHFSKEGDREVTPPAVRIAMIGIALGLAVMILSV
                     AIVIGFKKEVRNKVIGFGSHIQITNFDSNSSYESQPIAVSDTLLNALDAFPGIRHVEK
                     FATKLGILKTDQDFQGIVLKGVDTDYDWTFFKDNLKEGEIFTIQPDKNSTDVIISKYL
                     SDLLGLKVGDSFLTYFVQDDVRARKFTITGIYETGFLDYDKMFVIADIKQIRRLNGWD
                     KDQVSGLELQVDDYDRLDQVAEDIYFDLTERQDRNGNTFYARSIKELNPMIFNWLDVL
                     DINVVVILALMLSVAGFTMISGLLIIILERTNMIGILKALGQNNNSIRKIFLYVSFFL
                     IGKGMLWGNIIGISLCLLQSHFHIIQLDPSIYYLDAVPIDLSLFSLFLLNIGTLAASM
                     LMMLGPSYLITKIDPAKSIRFE"
     gene            10942..11475
                     /locus_tag="ACZPB4_11685"
     CDS             10942..11475
                     /locus_tag="ACZPB4_11685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="very short patch repair endonuclease"
                     /protein_id="HIR1098908.1"
                     /translation="MTDLISKEKRSYIMSMIKGKNTKPEIIVRKYLFHCGFRFRVNVK
                     RLPGTPDIVLRKYKTAIFVNGCFWHGHEGCPEFRPPRTRVEWWTEKLNRNKARDARVR
                     EELRAMGWNTMVIWECQLKPKERQATLENVVRLLEKTYVESTYHAKFTPAYPLLEEEE
                     LPKVAEEEISYESAHHY"
     gene            complement(11472..12635)
                     /locus_tag="ACZPB4_11690"
     CDS             complement(11472..12635)
                     /locus_tag="ACZPB4_11690"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HIR1098909.1"
                     /translation="MFLLNTTELFLLGISLIGFVILSLYYLIAYARLLRASRRTDDTL
                     EEGNKLPVSIIIYAKNDSENLKKHLPALLTQDYPEYQVVVINDGSSDDTDDTLKFFQN
                     EYKHLYHTYVPSDARYLSRRKLAFTLGAKAAKYDILLFTEANCQPLNDQWLSAMVGGY
                     TPETSIVLGYCKYSNYKGFFHKLIAYDNLLTGLRYLSSALSHHPYTGNGRNLSYRKEL
                     FFKHNGYYQSLNLHAGDDDLFINEASTKENTKVIYTPDSLTEMDQIERFGIWKEMKVS
                     RAATQRYYKGSALTFYHLESTCFFLFQVSVIATVVIGLQGNWLISLIAVLLYLIRFII
                     KASVFGKSARMLQQSPTIGWLFLLEFIQPIFNGYVRIYRLFRSRKDYTFRLEN"
     gene            complement(12753..13910)
                     /gene="lysA"
                     /locus_tag="ACZPB4_11695"
     CDS             complement(12753..13910)
                     /gene="lysA"
                     /locus_tag="ACZPB4_11695"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010802325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HIR1098910.1"
                     /translation="MLKGTFPVEKFKQLSTPFYYYDVKLLQDTLDVVKTESGKYGYHV
                     HYAVKANANPRILSIIAANGLGADCVSGGEVQAALDAGFPADKIVFAGVGKADWEINL
                     GLDNDIFCFNVESAVELGIINELAAAKNKVASIALRINPEVDAHTHAKITTGMKENKF
                     GINLSQLGGVLDKLKEMKNVKLIGIHSHIGSQITDMSSFRNLVIRFNEIQEELEAHGV
                     TVENLNFGGGLGIDYYHPNHLSIPAFDNYFAAIHKLLQVRPGQQVHFEPGRSIVAQCG
                     TLISKVLYVKEGETKKFAILDAGFTELIRPAMYDAYHRIENISSDEAVETYDVVGPIC
                     ESSDVFGKDVELNKAHRGDLIALRSAGAYGEVMASQYNCRHLPKAYYSDTI"
     gene            complement(13973..15289)
                     /locus_tag="ACZPB4_11700"
     CDS             complement(13973..15289)
                     /locus_tag="ACZPB4_11700"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009000030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HIR1098911.1"
                     /translation="MKVLKFGGTSVGSAQRMKDVAKLITGDRKIVVLSAMSGTTNSLV
                     EISDYLYKKNPDGANEIINKLAMKYMGHVEELYSTEEYKQKAKELIKSHFEYIRTFTK
                     DLFTLFEEKVVLAQGELISTGMMNLYLNECGVKSVLIPALDYMRTDKNAEPDPVYIKE
                     KLVKLLADNKDADLYITQGYICRNAYGEIDNLQRGGSDYSASLIGAAIGAEEIQIWTD
                     IDGMHNNDPRIVQGTSPVRQLHFEEAAELAYFGAKILHPTCILPAKLNNIPVRLLNTM
                     QPDAPGTLISNAIEKGKIKAVAAKDNITSIKIKSGRMLLATGFLRKVFETFENYQTPI
                     DMVTTSEVGVSVTIDNRKHLEEIVDDLKKYGTVTVDEDMVIVCVVGDLEWDNIGFEAR
                     IVQAMKDVPVRMISYGGSNYNVSLLIKASDKQRALQALSDHLFNNK"
     gene            complement(15356..16033)
                     /locus_tag="ACZPB4_11705"
     CDS             complement(15356..16033)
                     /locus_tag="ACZPB4_11705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HIR1098912.1"
                     /translation="MEEDILLKLENVEICREENRVLHDACLTLRNGEFVYVIGKVGSG
                     KSSLLKSLYCEIPILRGEARIMDYNLTKMKRKDIPYLRRKLGIVFQDFQLLTDRSVSK
                     NLEFVLKATGWKKKSEIKERIDNVLRQVGMQDKGYKMPHELSGGEQQRIVIARALLNN
                     PKLILADEPTGNLDPETSGQIVQLLHDICQQGTAVIMTTHNYTIVHNYPARIVKCENA
                     CLSDVRE"
     gene            complement(16042..16638)
                     /gene="hisIE"
                     /locus_tag="ACZPB4_11710"
     CDS             complement(16042..16638)
                     /gene="hisIE"
                     /locus_tag="ACZPB4_11710"
                     /EC_number="3.5.4.19"
                     /EC_number="3.6.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004635 - phosphoribosyl-AMP
                     cyclohydrolase activity [Evidence IEA];
                     GO_function: GO:0004636 - phosphoribosyl-ATP diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphoribosyl-AMP
                     cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE"
                     /protein_id="HIR1098913.1"
                     /translation="MKLDFEKMGGLIPAIVQDNNTSKVLMLGFMNQEAYDETVSTGKV
                     TFFSRTKNRLWMKGESSGNTLQVVSITADCDNDTLLIKAIPAGPVCHTGADTCFGEKN
                     VEDIMFLKYLQNFIERRRQEMPEGSYTTTLFQKGVNRMAQKVGEEAVETVIEATNGTE
                     DGFIYEASDLVYHLIVLLTSKGLRLEDLARELKKRHKG"
     gene            complement(16655..17410)
                     /gene="hisF"
                     /locus_tag="ACZPB4_11715"
     CDS             complement(16655..17410)
                     /gene="hisF"
                     /locus_tag="ACZPB4_11715"
                     /EC_number="4.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016277827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000107 - imidazoleglycerol-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="HIR1098914.1"
                     /translation="MLAKRIVPCLDIKDGKTVKGINFVNFRDAGDPVELGAQYSREGA
                     DELVYLDITASHEGRKTFTELVKQVAAHISIPFTVGGGINELKDVDRLLSAGADKVSI
                     NSAALRNPTLIEEIAKNFGSQVCVVAIDANFENNDWLCYLNGGRVPTDKYLFQWASEA
                     ESRGAGEILFTSMTHDGVKDGYANDALATLADTLHIPVIASGGAGKMEHFRDTFSNGK
                     ADAALAASVFHFGEIRIGDLKQYLKDEGINVRI"
     gene            complement(17428..18147)
                     /gene="hisA"
                     /locus_tag="ACZPB4_11720"
     CDS             complement(17428..18147)
                     /gene="hisA"
                     /locus_tag="ACZPB4_11720"
                     /EC_number="5.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003949 -
                     1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase"
                     /protein_id="HIR1098915.1"
                     /translation="MIELIPAIDIIDGKCVRLTQGDYATKKVYNEDPLEVAKMFEGNG
                     IRRLHVVDLDGAREGRIINYRILERIATRTSLIIDFGGGLKQEDDLEIAFESGAQMVT
                     GGSIAVKNPEMFTSWISKFGSEKIILGADAKEKKIAISGWEETTSQELIPFIKGYYDK
                     GITKVICTDIARDGMLQGPAIDLYKEIRDEIPFLYIIASGGVSSIEDIEKLSEAGIPA
                     VIFGKAIYEGKIQLKDLLRFT"
     gene            complement(18144..18734)
                     /gene="hisH"
                     /locus_tag="ACZPB4_11725"
     CDS             complement(18144..18734)
                     /gene="hisH"
                     /locus_tag="ACZPB4_11725"
                     /EC_number="4.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000107 - imidazoleglycerol-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisH"
                     /protein_id="HIR1098916.1"
                     /translation="MDVAIIKYNAGNIYSVDYALKRLGVTPIITADPELLNKADKVIF
                     PGVGEAFTTMEYLREHKLDQVILNLKQPVLGICLGMQLMCMRSEEGNADCLGIFPTEV
                     KRFIPQKHEDKVPHMGWNTLTNVKSGLFNERLENKFVYFVHSYYVPVNEYTAATTDYI
                     LPFSAALHKDNFYATQFHPEKSGSVGEVILKNFLKI"
     gene            19004..19077
                     /locus_tag="ACZPB4_11730"
     tRNA            19004..19077
                     /locus_tag="ACZPB4_11730"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19038..19040,aa:Asp,seq:gtc)
     gene            19111..19184
                     /locus_tag="ACZPB4_11735"
     tRNA            19111..19184
                     /locus_tag="ACZPB4_11735"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19145..19147,aa:Asp,seq:gtc)
     gene            complement(19286..19915)
                     /locus_tag="ACZPB4_11740"
     CDS             complement(19286..19915)
                     /locus_tag="ACZPB4_11740"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008155686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HIR1098917.1"
                     /translation="MDFYQVLEKRRTIRDFSNKEVTDEVLEKVLSAAFKAPTNDHLRQ
                     FEFIVVRGQENIARLISPVAENTKTIQQTQLKAAENVMDKDGYAMFVDALPKQQRMLI
                     QSNCLILPFFRQKDYPLCKPADQSSLNYFASAWAAVENILLAATAEGLACAFRIPIGN
                     EPEYVKHLVNAPAEYEFTCFLAIGYAAEDAHICKQKDIRVKERIHKNIW"
     gene            20048..20908
                     /locus_tag="ACZPB4_11745"
     CDS             20048..20908
                     /locus_tag="ACZPB4_11745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HIR1098918.1"
                     /translation="MEEMITPYELPEVENHSFFFIDQRIETHVEAKLHQHDAWELYYV
                     LHGYGTRMAGDTLQSFSAGDVALIPPSMHHYWEYTPLSADSDGCVHYLMVAFSHSFVV
                     RCMEVFPELRNRLAGLTFPVNALKLGLESSRIIRKILLRMNDMDELGRLCEMFRLLPV
                     LFTSSDHTFAGEPMNVERDVRRIQQICTYVMGHYVHPISLDDISAEVGMNRSAFCSYF
                     KRCKGMTFSQFVTEYRLNTACELLKHSQKQVSEICFAVGFNDVPHFNRIFKKLKGVTP
                     QEYRKKGTSG"
     gene            complement(21430..>21541)
                     /locus_tag="ACZPB4_11750"
     CDS             complement(21430..>21541)
                     /locus_tag="ACZPB4_11750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="zinc finger domain-containing protein"
                     /protein_id="HIR1098919.1"
                     /translation="SKNTYHDPCPVCGERIQKEAYLGGSIYYCPHCQRER"
BASE COUNT         5686 a         4465 c         5107 g         6283 t
ORIGIN      
        1 gccttggcga atgtcttgat cacggaccct gaattgatta tcttggatga gccgacgaac
       61 catttggatc tggagatgac cgaatggctg gaagattatc tgagccgggc caatatcagt
      121 atcttgatgg tgacgcacga ccgttacttc ttggatcgtg tttgtagtga gatcatcgag
      181 atcgataata agcaaatcta ttcgtataaa ggtaattata gctattatct ggagaaacgc
      241 caagaacgtg tcgaggcgat gaacgccgac gtggagcgtg cgaaaaatct tctccgtacg
      301 gaactggatt ggatgcgccg ccagccgcag gcacggggca cgaaagcgaa gtaccgtatc
      361 gatgcctttt atgagctgga aaagaaagcg aagcaacaac gggataccgg aaaggtgaac
      421 ttggacgtga aggcttctta cattggttcg aagattttcg aggcggtgaa tgtaagcaaa
      481 cgtttcggtg atttgaagat tacggaggat ttcaactata ttttcgcccg ttacgagaag
      541 atgggtattg tcgggaataa cggtacgggc aaatctacct ttatcaagat gctgatgggg
      601 gaggtggctc ccgatagcgg ccatttcgat gtcggcgaga ccgttcgttt cggttattac
      661 agtcaagatg gcttgaagtt cgatgagcaa atgaaagtga tcgacgtggt gcaggcgatc
      721 gccgaatacg tggatttggg taacggacag aagatgggtg tctcccagtt cctgaactat
      781 ttcctgttca cgccggagaa acagcatagt tacgtttata aattgagcgg tggcgagaag
      841 cgtcgtctgt atttatgtac ggtattgatg cgtagcccga acttcttggt gctcgatgag
      901 ccaaccaatg atctggatat cgtaaccttg aatgtattgg aagaatacct tcgtaacttc
      961 aaggggtgcg ctatcgtcgt ttcccacgac cgttacttta tggataaggt ggtagatcac
     1021 ctgctggttt tccggggtaa cgccgatatc aaggattttc ccggcaacta tacgcagtat
     1081 cgggattgga aagacgtgca agaccaactg gaaaaagagg cggaggctgc tttgcaagcg
     1141 agacaaaacc cggctccgga gaaaccgtct cgtcctgtca atgagcaaaa gaaaaaactc
     1201 actttcaagg agcggaaaga gttcgaggcc ctagaggagg agataccggc tttggaggca
     1261 gagaaagcgg agttggagac cgctatgagc agtggtactt tgtctacgga cgagctcatg
     1321 gctaaatctc aacggatcac ccaagtcatg gaagagatcg atgagaaaac gatgcgctgg
     1381 ctggagttga gcgagctggc ataagtaata aagaggaatg agcgagacta aacctgtact
     1441 ttggaaccgg aatttcgtcc aatgttgtat ctcttacttc ttgatgaatt tcgcctttta
     1501 tatgttgatg cctactatgc cggtctatct ggtggaagag ttgggcatca gcacgtccga
     1561 ggtggggatg gtcttgtcta gctatacgat cggcttgctg tgcgtgcgcc cgttctcggg
     1621 atatctggta gattgtttct cccgcaaacc gttatatgta ttcgccttca cgatattcgc
     1681 ctgtctgttc gccggttatt ggtttgcgat gacggtctat acgatcatgg cggttcgttt
     1741 catccaaggc gggttcatgg gactgacctc tgtttccggc aatacgatta cgatagacgt
     1801 aatcccttcc aagcgaaggg gagaaggcat gggcttttac ggattgacga tcaatctcgc
     1861 catgtctttg gctcctttgg tggcggtcgg gctgtacgat cggcatggtt tcttctggat
     1921 cataggggtc gctttggtga tcgcattggt cgggatcggc tccgtcgggc tgatccgtta
     1981 tccgaaacgg gagaaagtgc ctcgtccggc cttctcgttg gatcgtttta tcttggtaaa
     2041 agcgcttcct gcggccttgg cctatttgct ggtcgctata ccttatggga tgttgctctc
     2101 gttcgtggta ttatatggta aagagatcga ggtgccggac cccggctact tctttatatt
     2161 tatggcgatc ggtgtaggga cggcccgttt gatttccgga cggttggtgg accatggcaa
     2221 gatccatgtc gtgtccatcg tatccttggt ctctttagcg atctcgtttt ccgtgttcgc
     2281 taccgtacat acatcgtttg tctttttcgc ttgcgccttg gcgatcggta tcggttttgg
     2341 cgtgagtgta ccggcttttc aatgtctttt cgtgaatgtc gctccgcacc atatgcgcgg
     2401 tacggctacc tccacctact tgacctcttt cgatttcggg atggggatcg ggatgttatc
     2461 cgccggcttt atcgctaccc gtgccaatct ggctaccgcc tacggagtcg gggcggtttg
     2521 ttgccttctt tccttattcg tctatatccg cttggtaaaa gcctcgtacg agaggaataa
     2581 gctgatttct tgatctaaat gtggaactta aatcataaaa tatggataaa attaatagtc
     2641 tatttacaat tgggaatgtc aatgaggata atgctcaaaa aatatttgcg gatattgcaa
     2701 ctgaattatt cgagcattgc tttatcaaac aaggcgaagc cgtaaagtac aaattccttg
     2761 aagttgaatt ttacttttgg agtgaagccc ataaagataa caagcttgat aatgagggaa
     2821 aaaaagaagt gccttttgtc tacccacgta ataatactca gcctgcgcaa tacttggtac
     2881 atgctagcgg tatggatctt tgcttcaaat ccgataatgg ctatggtggc atattgattc
     2941 gttcattgtt acgaatagaa ggtaaagagc agtcggtagt aactggtcct tgggattgct
     3001 gttatgcact cataaactat atgggaggtt cagaaaatgt gtttccgaaa ttgacttatg
     3061 gagaagaaaa agatactcag gtcgagttgg aaacagcaat acggcataat gttcctgtgg
     3121 gaagttctat gaagaatgca ccatattgtt tttacaacaa aaaatatatg cacaaaagtg
     3181 gaaagtgggg ctttgaagat gctgaactga aacgatataa tcccagcacg aggaaatcag
     3241 ttgcaaatac ttattcgata aaaccttgga atagataact cttacgatat ggtactgtca
     3301 gagaatcaaa agaataaagt atatttctcc aatctgttag ccttgaacta tccgtcaata
     3361 tggaaggaga tatgtaatgt cctatcaatc tatggttatt cggcaggcag attgacctat
     3421 accaaagatt attggtgtag agacttcatg ccgattcaag ttggaagcaa tgagttcgtg
     3481 cagttccaat atgatccgga ttatttgact gatttaagga agtataaaac gaatccgaat
     3541 gatacggtaa agcatatcac tgattttact cctaagatct caaagtcaaa gttgcttgtt
     3601 gatggaggga atatagttgt atgtaataat atcaacgaag agacttgggt cgtaatgact
     3661 gaaaaggttc ttatagagaa tcctgatttc tcaaaggcgg aaattacttc tatgttggaa
     3721 aaagatttgg gtgcaagaat agtatggcta ccatgggata ctagcgatga atgcggacac
     3781 acagatggaa ttgttaattt tattaatggg ttatcgtcca aaccttctat catggcatat
     3841 ttttctcttt atcctaagaa tatcgctaaa gaaatgagaa aactcttgaa tgatgtattt
     3901 gatactcatg aattgatttt cacgcatgat gaaaagaata actgggccta tgttaatttg
     3961 cttcgcacaa aagatttcat catagtaccc ggattaggaa cagattctga caatgaagcc
     4021 atggggcaga tagagaggtt atatcccgat tataaaggac gaatccatca aatcattatt
     4081 gcacctattg ttgaagaata tggaggagct ttcaattgtt tgacttggac tgtaaataca
     4141 gaagatattg attcatacat ttcgattccc ggtttcgtct aaccccatgg cgtacttcgt
     4201 cgattcttcc ttttctagcg ggaaacctca ccctatattt gtatcaaaga tcacagagaa
     4261 ataggttttt aaggtttaac aaatgaaagg aataggtagt atgaaacgtt tagtaatggc
     4321 tatgtcagcc ttgttggtaa gtgtgacaat gagttttgcg caggaatcga gcttacataa
     4381 agaaccgttt gtagtcaatg tgggccaatt ggtaagctat ctggaattac gtcccagcca
     4441 gattaatgag gtagcgatga tcaacgatta ttttagggaa aagcaaagcg agggcttgag
     4501 gggaagtcat aaaatgcggg ataaacggat gcggcaagcc gtatttggca acttaaagtt
     4561 gatgaaaaag gcgttaagca ccgatcaata tcggaaatac gtggctttga tcaacgtaac
     4621 gaacaataat aaccggatga tgagcgggct ttccttcccc gatgtttatc tagccgataa
     4681 ataagtaaag gatagatgta aagtatcaag ctattgcata aaaagtatct tgtgactgta
     4741 tctattctat aaaccatgtc gtggtctgta tagatcatgt cgtggttttt atagaccacg
     4801 ctgtggtttg tataatccac gacggagatt atagaataga tacggtatcg tataagaata
     4861 cagctaggct tgtataagaa tatatctagg cttttgtttg tttataaacg gtgtctatga
     4921 tgaaatagat agtgtttatc gtaatatgtg ttacaaaatg attgctatat gccttgatat
     4981 atatcaataa cgtcaattgt ttgcaaaaat taaccgtatt gaagagcaat gttataaaac
     5041 atactgttat atttgcagta acaaaaagag aaagatagaa gatgcggaaa cgccgcattt
     5101 attagttaag gtcttagttt aggtttaaat tttaggtatt atgagacgtt taggtatgat
     5161 ggtagtcgct ttaatgatgg tagcgacaat gagctttgct caaaaggtta gtgattcaaa
     5221 gagtatgagt ttcgataagc taagcagata tttgcagctt gacgcaaacc agatcgctga
     5281 ggtgtcagag attaatactt acttcgagaa tcaattaggt caacccctgt ctgcggaagc
     5341 gctttgcaat aacgcaagac cggaagaaac tcgcaacgca ttgttgtgta atttgaaact
     5401 gatgaaacgt gcattgacta aagatcaata tcgtaaatat gtagcgttga ttaatgtgac
     5461 tcgcactaat caggaagata aggtttctaa tccgcttttg gacagctatt tggctgagaa
     5521 gtaattaagc caatgtgatt gggctatgtg tttttaaggt ttttgtttag gtttaacaat
     5581 ttaaggtttt taggtattat gaaacgtttt ggaatggcag tcgcagcctt attgatgtgt
     5641 gcgacaatga gcttcgctca gaaaccgagt ttgagtagag aaccgtttgt ggtaagtaca
     5701 gagaagttag cgaactattt gcaattgact ccgagccagt tggacgaggt cgctaatatc
     5761 aatgaatatt ttatcgagat gcagaacgcg agcgtaaaag ctagcgctaa attgcaggac
     5821 aagaagatgt atcaggcggt ttacggtaac ttgaagttga tgaagaaggc tttgagcccg
     5881 gatcaatatc gtaagtatgt tactttattg aacatcacga acaataacaa ccgtacgctg
     5941 ggtgttaata cgttcccgga agtgtactta gcggataacg caagtaagta atttatacta
     6001 tataagagtg tgtcccccac tatttcctgt caaaaggtaa atagtgggga tacttttttt
     6061 taaggctcgc gtataaatcg aagaagattg tgtaagtttg cggcgtttta caaataacgc
     6121 ttaattcgag tcatgacaac acaaaaactt ttagtccctt ctaatgctac tttgaagaga
     6181 aatgtaatgg actactcctt aatcgtggta ggttcatttt tgcaggcact tagttacgtg
     6241 cttttcctag cgccttacaa aatcgtaccg ggaggtgtgt atggtatctc tatcgtaatc
     6301 cactatgtga cgaaagattt gttcccgttc ttcccggatg gtttgccgat gggtgcgacg
     6361 gcgctttgct tcaatatccc gttgatgatt ttggcgatga aaaagatcgg attgtcttcc
     6421 ggcccgaaga cgatcgttac tttcttgctg atctctatat ttaccgactc attatcttat
     6481 ttccttaccg atccattggt ggagaacgat gcctttatcg ccgcctttta cggtggagct
     6541 attttaggat tgggtgtgac ttgtattttc cgggcgcaaa gtacgagtgc cggtacggat
     6601 gtattggcac gtgtgattgc taatgactcc aacttgaagg tcagcaatat gatcatcgta
     6661 ttggattccg cggtcgtatt gttgggcttg atcgtattta aggattgggc ggtacctttg
     6721 tattcttggt ttactatttt cgtatatgga aaaatcgtgg agatgttcca gacggagaat
     6781 ccgaaccgtg ccgtcttcat tgtctctcgt aagacacagg agttgaagac cttgatagtc
     6841 gataaaatgg gtatgagggg tacttttatt cacggtaagg gaatgtatca gggaaatgag
     6901 actgagatta tattcacgat cgctgaacga aaagatatgc cccgcttgaa agatgaggtg
     6961 aaagagatcg atccgaatgc ctttgtttct acgatgcacg ctagcaagga ttcgccacgg
     7021 ccgggtattt aatagaatta agaattattc cgtatatttg tgggtaggct aatattaata
     7081 tcggttttga atgatggata gaagaggttt tttgaagaat gctacgcttg tgagcgctgc
     7141 ttgtttgatg gatttcaggg aggctttggc gtggggcgct aaggatgctg aagtaggaaa
     7201 agcatggaaa ggatggaaaa aggggcagtt ccagattcat ctgatttata ccggggtgtc
     7261 ggaatcgatg ttcttgattt tccccgacgg tacaacgatg ctgcttgatt gtggtgatca
     7321 taatgcggtt gggcgcggta aattggctgt gccggtgctt cccaatcccg atcggcatgc
     7381 cggggagtgg atctcacgct atgtccggag agtgaaccct cagaaggatt atgttgatta
     7441 tatgatgttg acgcactatc attcagatca cggtggcaac aataaattct acgctcgtaa
     7501 ggagacgagg gatggtaagg attactacct aagtggattc tctcaggctg ccgagtacct
     7561 tacgtttggc aaggcttttg accgttgctg gcccgactac aacgatcctc ttcctttgac
     7621 ccaggaggca gccgatgctt ttgagcacat gaaggatttt tacgactata tgttggctca
     7681 taagaagatg gagattgaga agttctgtct tggcgaaacc aaccagatcg ccatgaagaa
     7741 agacgctacg gcatatccgg gattctcggt aagaaatatc tgtgccaacg gccgcattgc
     7801 cgataaggaa gggaatatac gtgacctcta tgcggagcgc aagaaatcca atccggttaa
     7861 gttcagtgaa aacggaatga gcctgggcat gatctttacc tacggcgatt tcaagtttta
     7921 tacggcggga gacttctcgg atggctggga gttgcctaat ggaaagagat tcgagataga
     7981 ggatgcgata gccgacgtgg ttgagccggt gagtgtggcg aaaatcaatc accacggaca
     8041 caagtcaatg actgataagc tcgtggctgc gttgcgtccg cgtgtagttg tcaacaacgt
     8101 gtgggatcag cttcatacgc tgccctcggt catggagcgt ttttataacc ggaatcttta
     8161 tcccggcgag cgcatcgtgt gtcctaccgt gttccctgca gaacgtcgtg ccgaggatgc
     8221 cggacagccg tggcttgata tacttaaccc ctcgtcgttt gatgccggtc atgtgattgt
     8281 caatgtcgag gagggaggta aggactattc ggttacttac ctcactgcca atgatgagtc
     8341 gatgactgta aagagcgtga tgcggttcaa gtcataaacg gcttgaattt ggtgtcaact
     8401 gtcaactaaa atgcctatct ttgcatcata aaaacgaata aatatagaat aataatgccc
     8461 aacatctcac aaagaggagt cgaaatgccc gcttccccga tccggaagct ggctccattg
     8521 gccgatgctg ccaaacagag aggagttcat gtgtatcacc tgaatatcgg tcagcccgac
     8581 cttcccactc cgcgagcggc actcgatgcg atccgtaatg tcgatcgtac ggtgttggaa
     8641 tatagcccta gtcagggata tcgcagttat cgcgagaagt tggttggata ttataaaaag
     8701 tatgatatta atcttacggc tgacgatatt atcatcacta ccggtggttc ggaggctgtt
     8761 ttgtttgcct tcttgagttg cttgaatccg ggtgatgaga ttatcgtacc ggaacctgct
     8821 tatgccaatt atatggcatt cgctatctcg gcaggagccg tgatccggac agtgacgact
     8881 acgatagagg aaggattttc tcttccgaaa gtggaaaaat tcgaggagtt gatcaatgag
     8941 cgtaccaaag cgatcctgat ctgtaacccg aacaatccta cgggttattt gtatacgcgt
     9001 cgtgagatga atcaaatccg ggatatcgta aagaaatatg atctttatct tttctcggat
     9061 gaggtatacc gggagtttat ctataccggt tccccgtata tctcggcttg tcatctggaa
     9121 ggtatcgagc agaacgtggt attgatcgat tctgtctcca aacgctattc ggaatgcggt
     9181 atccgtatcg gtgcgttgat tacgaaaaat gccgaggtgc gtagtgccgt catgaagttc
     9241 tgccaagctc gtttaagccc gcctttgatc ggacagatcg ctgccgaggc ttctttggat
     9301 gcttccgagg agtatgcccg tgagacttat gacgagtatg tggaacggcg taaatgcttg
     9361 atcgatggct tgaaccgtat tcccggcgtt tattctccca taccgatggg cgctttctat
     9421 acggtggcta aacttccggt ggatgatgcc gataagttct gcgcttggtg tctggaagag
     9481 tttgaatacg agggtcagac ggtcatgatg gcaccggcgt cgggttttta cacaacaccg
     9541 ggacttggta agaatgaggt tcgtatggcc tatgttttga aaaaggaaga cctggcgaaa
     9601 gctttgacgg tgttatcaaa ggcgttggaa gcttatccgg gaagaatgtt ataaatgaat
     9661 ttagagctat ttatcgccaa aaagatacat ttcagtaagg agggggatcg tgaggttact
     9721 cctcccgctg ttcgtattgc catgatcggg atcgccttgg gattggcggt gatgattctt
     9781 tcggtggcga tcgtgatagg ctttaagaaa gaggtccgga acaaggtgat cggtttcggc
     9841 tcgcatatcc agatcacgaa tttcgatagt aattcttcct atgagtcgca gccgatagcg
     9901 gttagcgata ctttattgaa tgcgctcgat gcattccccg gtattcgcca tgtcgagaaa
     9961 ttcgcaacga agctaggtat cttgaagact gaccaagact ttcaaggtat tgtcttgaaa
    10021 ggggtggata cggattatga ctggactttc ttcaaggata atttaaaaga gggcgagatc
    10081 tttacgatcc agccggataa gaactctacg gatgttatta tttccaagta tttgtcagat
    10141 ctgctaggac taaaggtagg ggattctttc ctgacttatt ttgtgcaaga cgatgtgcgt
    10201 gcccgtaagt tcacgatcac ggggatttat gagacgggtt tccttgatta tgacaagatg
    10261 ttcgtaatcg ccgatattaa gcagatacgt cgcttgaacg gttgggataa agatcaagta
    10321 agcggactgg agttgcaagt ggatgactat gatcgtttgg accaagtggc cgaggatatt
    10381 tatttcgatc tgacggaacg gcaagaccga aatggtaata cgttttacgc ccgctcgatc
    10441 aaggagttga acccgatgat ctttaattgg ctggatgtgc tagacattaa tgtggtggtt
    10501 atcttggcgc tgatgctttc cgtcgcaggg tttaccatga tctcaggatt attgatcata
    10561 atcttggaac gtaccaatat gatcggaatc ctaaaagcct tgggacaaaa taataacagt
    10621 attcgcaaga ttttcttgta tgtctctttc ttcttgatcg gcaaaggaat gttgtggggg
    10681 aatatcatcg gtatctctct ttgtttgctt caatctcatt tccatattat ccaattagac
    10741 ccttctattt attatttgga tgccgtgcct atcgatctga gtctattttc actgttcctt
    10801 ttgaatatag ggacattggc cgcctccatg ttgatgatgc tgggaccttc ctatttgatt
    10861 acgaagattg atccggccaa gagtatccgt tttgaataaa agccgtatct ttggcatacg
    10921 ttctagtttt gccggattga tatgacagat cttatctcta aagaaaagcg tagctatatc
    10981 atgtctatga ttaagggcaa gaatacaaag cccgagatta tagtccgtaa atacctgttc
    11041 cattgtggct ttcgctttcg tgtgaatgta aagcgccttc ccggtacccc tgatatcgta
    11101 ttgcgtaaat ataagaccgc tatcttcgtg aacggctgtt tctggcatgg gcacgagggt
    11161 tgcccggaat ttcgtcctcc ccgtacccgg gtagagtggt ggaccgagaa actaaaccgg
    11221 aataaagctc gggatgcccg tgtacgtgag gaattacgag cgatgggctg gaatacgatg
    11281 gtgatttggg aatgccagct taaacctaaa gaacggcaag ctactttaga aaatgtcgtc
    11341 cgtttattgg aaaagacgta tgtggaatct acctatcatg cgaagtttac cccggcttac
    11401 ccgctattag aggaggaaga acttcccaaa gtggcggaag aagagatatc ctatgagagt
    11461 gctcatcatt attaattctc caaccggaac gtataatcct tcctacttct gaaaagccgg
    11521 taaatacgga catatccatt gaatatgggt tgaataaact ccaacaggaa taaccaaccg
    11581 atagtagggc tttgttgaag cattcgagcc gatttgccga aaacgctcgc cttgattata
    11641 aaacgtatca aatataataa tacggcgatc aaggagatta gccagttgcc ctgtaatccg
    11701 atcacaaccg tagcgataac cgatacttgg aaaaggaaga aacaagtgga ttcgagatga
    11761 tagaatgtca aggcgcttcc tttgtaatac cgttgagtgg cggcacggga aaccttcatc
    11821 tctttccaga ttccaaaacg ttcgatttga tccatttccg ttaggctgtc cggagtgtag
    11881 attactttcg tattctcctt ggtcgaggct tcgttgatga ataagtcatc gtctcccgca
    11941 tgcaagttca aggattggta gtaaccatta tgcttgaaga ataactcttt ccgataagat
    12001 aaatttcgtc cgtttccggt atatgggtga tgggagaggg cggaagatag ataacgtaaa
    12061 cccgtcaata agttatcata ggcgatcaac ttatgaaaga atcccttgta gttgctgtat
    12121 ttgcagtagc ccaagacaat actggtctcg ggtgtgtatc caccaaccat ggcagataac
    12181 cattgatcgt tgagcggttg gcaattcgcc tccgtgaata gaagaatatc gtatttggcc
    12241 gctttcgcgc ctagggtaaa cgccagttta cggcggctta ggtagcgagc gtccgagggg
    12301 acgtaagtat gatacaaatg tttatactca ttttgaaaga actttagcgt atcgtcagta
    12361 tcgtcgcttg agccatcgtt gataacgact acctgatatt cagggtaatc ttgtgtaagt
    12421 aacgctggaa ggtgtttctt gaggttctca gaatcatttt tagcgtatat gatgatggat
    12481 acggggagtt tattaccttc ctctaaggta tcatccgttc gtcttgacgc acgtaaaagg
    12541 cgggcataag cgatcagata ataaagagat aagataacga accctatcaa agagatcccc
    12601 aaaaggaaaa gctctgtagt attgagtaga aacataataa tgtaccaatg tattaaatga
    12661 caatgtgcta aaacgacaat ataccaatgc gatacctaaa acgtattcgc atgggtatat
    12721 tggtatagta gcgaagcgct attacctctt tattatatcg tatcggaata ataggctttc
    12781 ggtaaatggc ggcagttgta ttgggaggcc atgacctcgc cataagcgcc ggcggaacga
    12841 agggcgatca agtcgccacg atgagcctta ttcaactcta catccttacc gaatacatcc
    12901 gatgactcac agatagggcc cactacatcg taagtctcta ctgcctcatc gctgctgatg
    12961 ttctcgatac ggtgataagc gtcgtacatc gccgggcgga tcaattccgt gaaacctgca
    13021 tcaaggatag cgaatttctt cgtctctcct tccttgacat ataatacctt agagattaat
    13081 gttccgcatt gagcgacgat cgaacgtccc ggctcaaaat gtacctgttg acccggacgt
    13141 acttgaagca gtttatgaat ggccgcgaaa tagttatcga aagccgggat cgataaatga
    13201 ttcgggtgat agtaatcgat acctaatcca cctccgaagt ttaggttctc cactgtaacc
    13261 ccatgagctt ccagttcttc ctgtatctcg ttgaaacgaa ttaccaaatt gcggaagcta
    13321 gacatatccg tgatctgtga accgatatgg ctatggatac cgatcaactt cacattcttc
    13381 atctccttta atttatccag tacacctcct aattggctaa ggttgatacc gaatttattc
    13441 tctttcatac ccgtcgtgat cttggcatgc gtatgggcat ccacttccgg gttgatacga
    13501 agggcgatag aggctacttt atttttagcg gccgccagct cattgatgat tcccagctca
    13561 acggcagatt ccacgttaaa gcagaaaata tcattgtcca gtcctaggtt gatctcccaa
    13621 tccgctttgc caacaccggc aaagacaatc ttatcggcag gaaaaccggc atctaaagct
    13681 gcctgtacct cgccgccact tacgcagtct gcgccaaggc cgtttgccgc tatgatggaa
    13741 aggatacggg gattggcatt cgctttcacg gcataatgca cgtggtaacc atatttcccg
    13801 gattcggttt ttactacgtc taatgtgtct tgcaatagct tgacatcata ataataaaaa
    13861 ggcgtagaaa gctgcttgaa cttttctaca ggaaatgttc ctttgagcat attatacgaa
    13921 attatataaa gataaataag ggcagtctgt aaaaggccgc cctcgtttgt ttttatttgt
    13981 tgttaaataa atgatcgctt agagcttgca gcgctctctg cttgtccgag gccttgatca
    14041 gcaaggagac gttgtagttg cttcctccgt aggagatcat acggaccggg acatccttca
    14101 tagcttgtac gatacgagcc tcgaagccga tgttatccca ttctaggtcg ccaaccacgc
    14161 aaacgataac catatcctcg tctacggtca cggttccgta cttcttcaaa tcgtcaacga
    14221 tctcttccag atgcttgcgg ttatcgatcg taacggagac acccacttcg gaagtcgtaa
    14281 ccatgtcgat cggagtctgg tagttctcga aagtctcgaa taccttacgc aagaaacctg
    14341 tagctagcaa catacgtccg ctcttgatct tgatagaggt aatattgtct ttggcggcga
    14401 ccgctttgat cttacctttt tcgatagcgt ttgagatcaa tgtacccgga gcgtccggct
    14461 gcatcgtatt taacaaacga accgggatgt tgttcaattt agccggcaat atacaagtcg
    14521 ggtgaaggat cttggctccg aaataagcta attcggcagc ttcctcgaaa tgcaattgac
    14581 ggactggaga cgttccctgt acgatacgag ggtcgttatt gtgcataccg tcgatgtctg
    14641 tccagatctg gatctcttcc gcaccgatag ccgcgccgat taaggatgcg ctatagtcgc
    14701 taccacctcg ttgtaggtta tcgatctcgc cgtaagcgtt gcggcagata taaccttgtg
    14761 tgatgtatag atcagcatcc ttattatcag cgagtaattt caccaatttc tctttgatat
    14821 agacagggtc cggttccgcg ttcttatccg tacgcatata atccaaagcc gggatcaata
    14881 cggatttcac gccgcattcg ttcaaataaa gattcatcat acccgtagag atcaactctc
    14941 cttgtgccaa gacaaccttt tcctcgaaca aggtaaacag atccttcgtg aacgtacgga
    15001 tatattcgaa atgagatttt atcagttctt tggccttctg tttatattcc tcggtgctgt
    15061 atagttcctc aacatggccc atatatttca tggcaagctt gttgatgatc tcattcgctc
    15121 cgtctgggtt ctttttgtac aggtagtcgg aaatctcgac taacgagttg gttgtacccg
    15181 acatggctga caatacaacg atcttacggt ctcccgtgat cagtttcgct acatctttca
    15241 ttctctgtgc agatcccaca gaagtaccgc caaactttaa aactttcatc ttcttttgtt
    15301 ctatattaaa ttgttttctt tttcaatcga atgcgaccgc aaagttacaa aaaaattatt
    15361 ctctgacatc acttagacag gcattctcgc attttactat gcgggcagga taattatgca
    15421 cgatcgtata gttatgagtg gtcataatca ccgccgttcc ctgctggcag atgtcgtgta
    15481 agagttgtac aatttgtccg ctcgtctccg ggtccaagtt gccggtcggc tcatccgcca
    15541 gtatcaactt ggggttgttc agaagggcac gggcaataac gatacgttgt tgttccccgc
    15601 cggatagctc atgcggcatt ttatagcctt tgtcttgcat gcctacctga cggagcacgt
    15661 tgtctatccg ttccttgatc tcgcttttct ttttccatcc ggtggctttc agcacgaatt
    15721 ccagattctt ggagacggaa cggtcggtca acaattgaaa atcttggaag acgataccta
    15781 gtttcctacg caaataaggg atatccttcc gcttcatctt ggtgaggttg taatccatga
    15841 tacgtgcctc gcctcgcaag atcggtatct cgcaatacaa ggacttgagc aggctgcttt
    15901 taccggagcc taccttcccg atcacatata cgaactctcc gttacgaagc gtgaggcatg
    15961 cgtcgtgtaa taccctgttt tcctcacggc atatctccac gttctctaat ttgagtagaa
    16021 tatcttcttc catagaattt atcaaccttt atgtcttttc tttaattcac gggcgaggtc
    16081 ttccagacga agtcccttgc ttgtcaataa tacgattaag tggtaaacca agtcggatgc
    16141 ctcatagatg aagccgtctt cggttccgtt ggtcgcctcg ataacggtct ctaccgcttc
    16201 ttcgccgact ttctgggcca tacgattcac gcctttctgg aataaggtag tcgtatagga
    16261 accttccggc atttcttgac ggcgacgctc gatgaagttc tgcaagtatt tcaagaacat
    16321 gatatcctct acgttcttct cgccgaaaca agtatccgct cccgtatgac aaaccggtcc
    16381 ggctggaatc gccttgatca ataatgtatc gttgtcgcaa tccgccgtga tgctaaccac
    16441 ctgcaacgta tttccgctac tctctccctt catccacaaa cggtttttcg tgcggctaaa
    16501 gaatgtaacc ttacccgtac ttactgtctc atcataagct tcttgattca tgaagcccaa
    16561 cattaatacc ttactagtgt tgttgtcttg tacgatagcg ggtattaatc cgcccatttt
    16621 ctcgaaatct aatttcatct ttatatataa tgtgttatat ccttacattg atcccctcgt
    16681 ccttgaggta ttgcttcaag tcgcctatcc gtatctcgcc gaaatggaaa acgctggccg
    16741 ctaaagccgc gtccgctttc ccgttggaaa acgtatcccg gaaatgttcc atctttcccg
    16801 ctccaccgga ggcgataacc gggatatgca acgtatcggc caaggtagcc agagcgtcgt
    16861 tcgcgtatcc gtcttttacg ccatcgtgcg tcatactggt gaaaagtatc tcgccggcgc
    16921 cacggctttc cgcttccgag gcccattgaa acaaatactt atccgtcggg acacgccctc
    16981 cgtttagata gcatagccag tcattgttct caaaattagc gtcgatagcg actacgcata
    17041 cctgactacc aaagttcttg gcgatctcct cgattaatgt cgggttacgt aaagccgccg
    17101 agttgattga gaccttatcg gcgccagcgc taagcaaacg atccacgtcc ttcaattcgt
    17161 tgatacctcc acccacggta aaagggatgc tgatatgggc cgccacttgt tttaccaact
    17221 cggtgaaagt ctttcgcccc tcgtgtgagg cggtaatatc caagtacact aattcgtcgg
    17281 ccccttcacg gctgtactgg gcacccaact ccacggggtc tccagcgtcg cgaaagttca
    17341 cgaagttgat gccttttacg gtctttccat cctttatatc cagacaggga acaattctct
    17401 tggctagcat atatctattt tattatttca agtaaaacga agtaaatctt tcaactggat
    17461 cttcccttca taaatggcct tgccgaaaat gacagcggga atcccagcct cagataattt
    17521 ctcaatatcc tcgatcgagc ttacgccacc gctcgctatg atataaagga aggggatctc
    17581 gtcccgtatc tctttatata aatcgatagc cgggccttgc agcataccat cccgtgcgat
    17641 atccgtgcag atcaccttgg taatcccctt gtcgtaatat cctttgataa aaggaatcaa
    17701 ctcctggctg gtcgtttcct cccaaccact gatggcgatc ttcttttcct tggcatcggc
    17761 ccctaatatg attttctcgc taccgaactt gctgatccaa gaggtgaaca tttccgggtt
    17821 cttcacggcg atactgcccc cggttaccat ctgggcgccg ctttcgaagg cgatctccag
    17881 atcatcctct tgtttcaagc cccctccgaa atcaatgatc aaggaagtcc gggtcgctat
    17941 ccgctcaagg atacggtagt tgatgatgcg tccttcacgg gctccatcca aatctaccac
    18001 atgcaaacgc cggatgccgt taccctcgaa catcttggcc acctccagag gatcttcgtt
    18061 gtaaaccttc ttggtcgcgt aatctccttg cgtcaaccgg acgcatttgc catctattat
    18121 atctatagcg ggaataagct caatcatatc tttaaaaagt ttttcaatat aacctctcct
    18181 accgatccac ttttttccgg atggaactgt gttgcgtaga agttgtcctt atgtaaagcg
    18241 gcgctgaacg gaaggatgta atcggtcgta gccgccgtat attcatttac aggtacataa
    18301 taactatgta cgaagtaaac aaatttgttc tccaatcgct cattgaatag gccgctttta
    18361 acgtttgtca aggtattcca acccatgtga ggaaccttgt cctcatgctt ttgcggaata
    18421 aaacgtttta cttccgtagg gaagatcccc aagcaatctg cgtttccctc ctccgaacgc
    18481 atgcacatca attgcatgcc gaggcatatc ccgagtaccg gttgctttag gttcaagatc
    18541 acctgatcca atttatgctc ccttaaatac tccatggtcg tgaaagcttc acctactccg
    18601 ggaaagataa ccttatccgc tttatttaat aattccggat cagccgtgat gatcggggta
    18661 acgcccaacc gcttcaaagc gtaatctacc gagtagatgt ttccggcatt atatttaata
    18721 atggcaacgt ccattgttgt taagcattta tattgagtcg caaaagtaac aaattatcat
    18781 tacataatta tgaatggcga ttgaaaagtt ccaaaatgaa atgtatttgt gataaactgg
    18841 tgtgatcggg aaggggaaat aaagaaaggg acgatcgctt atgtggacct atggaaagaa
    18901 tatttcagcg aaaagttgat tttttttact ccagctattg cagatttaaa aataatactt
    18961 acctttgcac cgcaatcgag agagatagcg ataaaagaaa agaggttcgg tagttcagct
    19021 ggttagaata catgcctgtc acgcatgggg tcgcgggttc gagtcccgtc cggaccgcct
    19081 ctttttcaaa attattattg attataaaat ggttcggtag ttcagctggt tagaatacat
    19141 gcctgtcacg catggggtcg cgggttcgag tcccgtccgg accgctttca aagaaagcaa
    19201 aataaagtaa agctctgtaa tttaaagatt acagggcttt ttcttttttc atcacttatc
    19261 aagatatggc ctttcgtatt tgggcttacc atatattttt gtgaattctc tctttcactc
    19321 ggatatcttt ctgcttacat atatgtgcat cctcggccgc ataaccgatg gcgagaaaac
    19381 aagtgaactc atattcagcg ggagcattaa cgaggtgttt cacgtactcc ggttcattgc
    19441 caatgggaat acggaaagcg catgccagcc cttccgctgt tgcggctaac aatatgtttt
    19501 ctacggctgc ccaagccgaa gcgaaatagt tcaaggaact ttggtctgcg ggcttgcata
    19561 agggatagtc cttttgtctg aaaaacggca ggataaggca gttgctttgg attagcatac
    19621 gttgttgctt gggaagcgca tcgacaaaca tagcatatcc gtctttgtcc attacgttct
    19681 cggcggcttt aagttgggtt tgttgaatgg ttttggtgtt ttccgctaca ggtgatataa
    19741 gtcgggcaat gttttcctgc cctctcacga caatgaactc gaactgtcgc agatggtcgt
    19801 tggtcggagc tttaaaagct gccgataata ctttttccag cacttcgtcc gttacctcct
    19861 tattggaaaa gtcccggatg gttcttcttt tctctaatac ttgatagaaa tccataacaa
    19921 tacatttaat agttatactt gttgttttca gcggcaaagt tatattgctt tattgtcgca
    19981 tatttgttgt attgttttat gtaattgtcg tatatttgta tcgaaccatt ttatatacga
    20041 ctaccttatg gaagagatga tcactcctta cgaattgccc gaagtagaga accattcatt
    20101 cttttttata gatcaacgaa tagagactca tgtagaagcc aaattgcatc agcacgatgc
    20161 atgggagtta tattacgtgt tacatggata tggaacccga atggcaggcg atacgttaca
    20221 gtctttttcg gctggtgatg tggcattgat accgccatcc atgcatcatt attgggaata
    20281 taccccttta tcggcagaca gtgacgggtg cgttcattac ttgatggttg ctttcagtca
    20341 ctctttcgtc gtgagatgca tggaggtatt tcccgaatta cgcaatcgtt tagcagggct
    20401 aacttttcct gttaacgcat taaagcttgg tttggaaagc tctcgtatca tacgcaaaat
    20461 attattgcgt atgaacgata tggacgaatt ggggcgattg tgcgaaatgt tccgcttgct
    20521 accggttcta ttcacttcat ccgaccatac ttttgcaggc gagcctatga atgtagagcg
    20581 ggatgtgagg cgtatacagc aaatttgtac gtatgtgatg gggcattatg tccatcctat
    20641 ttcattagat gatatttctg ccgaggttgg tatgaaccgt tctgcgtttt gttcctattt
    20701 caagcgatgc aagggaatga cattctcaca atttgttaca gagtaccgct taaatactgc
    20761 ttgcgaactt ctgaaacact cgcaaaagca ggtgtcggaa atctgttttg cagtaggatt
    20821 caatgatgtt ccacacttta atcggatttt taaaaaattg aaaggagtaa cgccacaaga
    20881 atatagaaaa aaggggactt ccggttaggc aatattttag gcttatgcga tattagtgga
    20941 gaatgatgtt gtaagcgaaa atgcgataac cttgacgttt tgtttgaaaa ttcgtggtta
    21001 tgatgacagg gcctttttgc gaatagaaga aatagggagt gctttatggt caaattatcc
    21061 attttaccct gtttttttgt atgaatatct ctattaggag acgaaagtaa tgggattagg
    21121 taacgcgaaa gccagtgtta ggcaacgcta ccgtatgtgt taggcgatac atacggtagg
    21181 aattgggtac gcaacctata gaaatgggcg acgcatccgt atgaaaagcg cctttctcct
    21241 gcataaatat gagataggat gaattaatct cgctagaatg aaagtgtata tttaagcaaa
    21301 gtgctataat acaattgatt gctgatattt tttctcgtat ttggtaacag tatgtacctt
    21361 tgcccggaaa aaacgattct ccggggcttc agattacata ttgtcatatt gtcaatttga
    21421 gcgtattact tatctttctc gctggcaatg cgggcaatag taaatgctgc ctccgaggta
    21481 agcctctttc tgtatccgtt cgccacagac ggggcaaggg tcatggtagg tgttcttcga
    21541 t
//
LOCUS       DBMDTB010000072        20956 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_847_length_20956_cov_12.288900, whole genome shotgun sequence.
ACCESSION   DBMDTB010000072 DBMDTB010000000
VERSION     DBMDTB010000072.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 20956)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 20956)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20956
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_847_length_20956_cov_12.288900"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..1766)
                     /locus_tag="ACZPB4_11755"
     CDS             complement(<1..1766)
                     /locus_tag="ACZPB4_11755"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2 protein"
                     /protein_id="HIR1098920.1"
                     /translation="MKKITVVCLALCSFLFGGDLFSVKAQILEKFTLPTPWTEEALKA
                     EIPLPEYPRPQMVRSEWLNLNGIWDYMGGKDLLDPVTATTPPAFPAKVEKIRVPYPPE
                     SELSGIARGGDTCLWYKRSFSVPQAWKGRNVLLNFGAVDRISSVFVNGKKVGTHTGGY
                     DAFSLNITDYLKSGENVLVVGAYDPNDGRAASGKNGSRGDYIFTSGIWQTVWLEPVEK
                     QYIFQIKLVPDLKNNRLEVIAYTEDKELKVTAIADNGTSEVARTEGNSNMSFYLPIRE
                     PRLWSPDDPFLYGLKLQLKDRKGKIIDEVSSYFGMRSVSMGKVDGVLRPLLNGEFVFH
                     IGLLDQGYWPDGAFTAPTDKALLYDIELAKRAGFNVIRKHIKVEPQRWYYHCDRLGLM
                     VWQDMPNLWEPDGEDSVAVRKQFRDELKVMIDQHVSSPSIVMWVPFNENWGAFEATDI
                     TAWVKKYDPNRWVNGMSGYNYAPGYRKAYGDPGNGDFVDMHHYGKIEPKAIPRPDDKR
                     AASLGEFGGKGLFVRGHMWPVRNDAYEMMLNREILTDTYVLMLTELEQMINYFGLSTA
                     IYTQTTDVEHEINGLVTYDRKV"
     gene            complement(1774..3207)
                     /locus_tag="ACZPB4_11760"
     CDS             complement(1774..3207)
                     /locus_tag="ACZPB4_11760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3863 domain-containing protein"
                     /protein_id="HIR1098921.1"
                     /translation="MRESNMNISVWRKWAIVWMVSVLSGFQLRAADPVVIPANTEPLT
                     IEGNRFVTLCIMIRTTPWEVSRDVKLHPRDEVDWHTLEGVRALREAFATNNPNGRLTW
                     GFTMNALEDGRKNYREIRDYVVECQKKYGDEVTYFPGYFPAMYLPRERVNREMSEAIE
                     IISKMVGNGYRPQSIMGGFLSADNLRYLAEKENIHVAHAVIWSQHNIDGGGADGSPSY
                     PFYPSTEHFCKPAQGKSDFIDCVNLDGWTMDFICARRSGQTGHGIDGYNSRRGVGPIE
                     TYKGWGLDLGHREVMHTEAIHFDKGLELNGFGWVANIWEAQMVHEFGKDLICDAMKMW
                     VTGTKERWPDTHFVTFGEFGELWRKQYKSNDDWNYRFVERGSGLGDSYNNLEIKWFMN
                     KEFRLALLRDWHTKNSPAYVIDFTRYDLPAHEPADPTPTKPAKDWSLINKINQKGLRP
                     QDKPVLIDKLEKEDQDLIRKYYPELFK"
     gene            complement(3194..4876)
                     /locus_tag="ACZPB4_11765"
     CDS             complement(3194..4876)
                     /locus_tag="ACZPB4_11765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098922.1"
                     /translation="MSFIKKIGLVCFIVFCCAGCRSAGEKLVESAAAPRIINIINFIR
                     QTDYRVENADSLLYETVCEQVKLVNKYDLPATFLLQYDALINPLYQDLLKSKLNAHSE
                     IGAWWELTQPQIEAAGIKWRGEHSWVSHANIAFSTGYTKEERERLVDVYMAKFKEIFG
                     TYPKSVGSWFIDAHTLGYMYDKYKIVASCNCKDQVGTDGYTLWGGYWNQAYYPSRVNA
                     YMPAQTEEGQIPVPIFRMLGSDPIYQYDDGLGQERQGVISLEPVYEKAGMDRRWVDYF
                     LESIVNQPCLAFNYAQAGQENSFTWSNMSKGLEMQIPILDSLRKENKIRVETLGESGA
                     WFKECFKVTPATAVTTLTDVRGEGNKTVWFNSRYYRANLLWEKGTFRFRDIHLFDESY
                     KSAYLEKPGDGNQFLFYTLPVVDGFMWSEGLDRAGLRIVRLDKDGDKEELSLDHPVVT
                     EIGKDTLVVSAEDSKGHAFKITFYETRFEVVALSKEADFSWALELKAAAGKELPFTVI
                     EDKAVNASFDGFNYVITCEKGHIRKPESGSDYVFRMFPSDQEIVIDCTNARK"
     gene            complement(5140..6804)
                     /locus_tag="ACZPB4_11770"
     CDS             complement(5140..6804)
                     /locus_tag="ACZPB4_11770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0019867 - outer membrane [Evidence IEA];
                     GO_function: GO:2001070 - starch binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RagB/SusD family nutrient uptake outer membrane
                     protein"
                     /protein_id="HIR1098923.1"
                     /translation="MKNYRIILGSFIVSALFLSSCQDIDLLPKDNMPDELFWKTPDDF
                     EKEVNWLYTRTETFGTKDTDSDIAYELNENTTSNGTLIAPNTDALWDSTFIDLRQSNM
                     IIEKSQTYEGDPSEIERYVAEARFFRAYSHFRLMAKYNDIPILTKVLTVDSPELYGSR
                     NKQQEVEDFILSELNEVYAKLPLQSELSSDEAGRVTQGAALALKARVALFAGTWAKYH
                     QHRSDYQQLLQQAIDAAAKVIDSGEYALYEGSGEESYRYLFINAGDNSKEGIFDSRYE
                     TDIRHHSDACPVYWGWRGTPTRKLADMYLCKSTGLPIENANSGFEGYATIKSEYENRD
                     PRMKQTFLMPGTDYISPQDGALTCPPQFTIRPETRTGYKLWKYMAETSVPSDKDVYDY
                     HIIRYPEVLLILAEATYEKDGAISDDILNKTINVIRSRKGVEMPPLTNAFVKSNGLDM
                     RTEIRRERTIELAFEGFRRDDLRRWKTAETELIGAIKGIKLKGSEYENLDVLNEGNPG
                     LTDENGFLIVEPAENRNFVTPKHYYYSLPLDELYLNPNLAPNNPGW"
     gene            complement(6823..10263)
                     /locus_tag="ACZPB4_11775"
     CDS             complement(6823..10263)
                     /locus_tag="ACZPB4_11775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HIR1098924.1"
                     /translation="MNFWNIARPEESPVLKKTLSIMRLTTLFSIACSLQISASVYSQE
                     TKLSLDVNNQTIKEVLFKIEKQSGFRFIYESEKVNLNKKVSVHVKEQTVETILKRLFA
                     GEGVKYEITENNFILINPSTKNEKAAPSSQAVLQKKNLVQGVVTDENGEPIIGANVVE
                     KGTTNGTVTDLDGKFTMEVSENGVLQISYIGYAMTELRPGKEANLNVKLREDALQMDE
                     VVVVGYGTVKRANLGGAVSRADAKAFESRPIQNAAQALQGEVPGLTITRAGGAPGSDM
                     TMKVRDVSSINGGTPLVLIDGAEGNINMINPSDIENISVLKDGTAAIYGARASDGVIL
                     VTTKSGKRNQKTSVAFDAYYSIKTPALLRKPANLLQHAEMALEITDGSFTPEYTRDQL
                     DLIRQNSDLVLTDAEWGRWTGYPQFFKDQDWNDMLIGNGNMQNYNVNISGGGERYSYM
                     LSLGHQREEGIPKFGEDVNKRYFVRAKSSVEIFKNLTYDLNLAYEASNRDYSSGLTEG
                     QNIWELIYKTRSWTPMYNPSGTFYTFEGFDNPAQVLEDGGMVNKTTGNITVNNQLRWK
                     VIDGLQLVGQAVIRKYDQDENVTNKKITNYDWDNNEVREKRTPNSAERRYQKTLSKNF
                     TLYADYKKNFNDRHDLSVMVGTSHESENYDRFTAKRINFDQQENMSLQLGSAQDQNAW
                     SEGNQWTINSFFSRVNYTFANKYVIEGTIRADGSSRFDPDHRWGWFPGVNAAWRVGEE
                     GFMKRLGWFEDLKVRASYGEMGNQSGIGLYDYIQLISLSNDYYPFGTGVKGQMATSGN
                     IISTSRTWETIQTTNVGFDFSTLNNRLYGSFDYFWKENKNMLIPKTYPSMLGADAPST
                     NSGHLSIHGWEISLGWRDQIKDFSYSVRFNISDAKNKVVDRVGSNLIKLGNNETPTGY
                     PLNSYFGYEFDGIIQNEQELEAYKSRFSEGGIPGDLSVGDAMYKDLDGDGKLSVLGDG
                     KEGSGDVKYLGDKNPRYNFGFNLSMAWKGFDLSAFIQGVGRRTMFLEGESRCPMPEAW
                     YQSAEYWYGKTWTPERTDAQYPAITLKDKRNYNYYVSTNTKFNVAYARLKNLQFGYTI
                     PQTLTSKAGLQKVRVYFSGEDLFEVHNTPNGWDPEENSGSITSYPFTRNYSFGINVVF
                     "
     gene            complement(10406..11389)
                     /locus_tag="ACZPB4_11780"
     CDS             complement(10406..11389)
                     /locus_tag="ACZPB4_11780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecR family protein"
                     /protein_id="HIR1098925.1"
                     /translation="MEKKKQIGEHIVDHLSERMNEEIVDPVLDEWLAEDESNQEDFKR
                     YKEIWKETGSYLEQETFNAQYAWDKIDRINKERDNKRKRLVNIGYIISGVAATLLLVL
                     GFSKMGVFDKQPEMLVRMTADYGSRSEVVLPDGSVVKLNSGSDITYSYNAKENIREVN
                     FQGEGFFDVSKNKIPFVIKMSNGLRLKVHGTSFNLQAYTDEKTVEASLVEGCIELDHG
                     NDKLLMNAGDMAIFDKQTNKMRPISGVLSHSYSWLEDKLYMDHMSLASVCKYLERRYD
                     VTIHLQKDLGNSIHYDGVIQEETITDILGVLSRLSDISYNVKGKNISITSK"
     gene            complement(11465..12007)
                     /locus_tag="ACZPB4_11785"
     CDS             complement(11465..12007)
                     /locus_tag="ACZPB4_11785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HIR1098926.1"
                     /translation="MQEVHADKVLMLAIGNNDYISYNKLFDRYYGRLCQYVYSLLMDR
                     NDAEDVVQELFLNLWKNRGRIEIKENVSGYLYRMAKHLALNFIRSKVQTGSLSENQDL
                     LLLSYEDNQLETEEFRIALYDCIDHLPDRSREVLLLHRVKGLKQKEISEKLSISVKTI
                     KNQIWMSLQKLKECLEMKEV"
     gene            complement(12457..13371)
                     /locus_tag="ACZPB4_11790"
     CDS             complement(12457..13371)
                     /locus_tag="ACZPB4_11790"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009016735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HIR1098927.1"
                     /translation="MKKLIYSFLFVLCSVFALQAESMVVATYNLRNANAGDSTNGNGW
                     GQRYPYIAQLVQFHGFDIFGTQEGKYHQLQDLKNAMPGYDYIGVGRDDGKQAGEYSAI
                     FYRTGKFEVLDHGDFWLSTITDRPNKGWDAVLPRICTWGKFRDKQTGFTFLFFNLHMD
                     HIGVQARAESAKLILKKLKEFPEKLPAILTGDFNVDQHNESYLLLDNSGIMRDSYQIA
                     DFRYVPNGTFNAFHADRKTDSRIDHLFLTKEFDVKKYGVLTDTYRSEAKDAKNEQNAN
                     FPKEVSMQKHVARVPSDHFPVMIVVEVK"
     gene            complement(13407..14249)
                     /locus_tag="ACZPB4_11795"
     CDS             complement(13407..14249)
                     /locus_tag="ACZPB4_11795"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HIR1098928.1"
                     /translation="MRNLIIVFISLFTFCIGISGQQKCKLNVGSFNLRYDNEGDKDDS
                     WVHRKDMAVSLVHFHDFDVFGIQEGLIHQVKELVKDDTYTYVGVGRDDGKEAGEHAAV
                     LFKKDRFKLLDSGNYWLSETQDKPSFGWDAQCRRVCSWAKLKDKVSGKEFYFFSVHFD
                     HIGKVARHESALIMLANIKKIAGDSPAICVGDFNGTPDSEPIQILKSDGLLLDSREIS
                     KTPPYGTVGTTNQFNLNAPMKNRIDYIFVTKGIQVNKYGTLNECQYGHFSSDHFPIMI
                     EAEF"
     gene            complement(14263..16092)
                     /locus_tag="ACZPB4_11800"
     CDS             complement(14263..16092)
                     /locus_tag="ACZPB4_11800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0019867 - outer membrane [Evidence IEA];
                     GO_function: GO:2001070 - starch binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RagB/SusD family nutrient uptake outer membrane
                     protein"
                     /protein_id="HIR1098929.1"
                     /translation="MKKNILLSGLVALLAIFSGCEMNEEPKSEASVDMVFSSENGLKT
                     YTYSFYNVLPSRGSAFRRDATADYGVKNSLGGMEVGAYTTNSATSWSWSALRNINFFL
                     ENNVNESLSTTIRDNYNGIARLFRARFYFDKLVQYGEVPWIDKVFNEAEDPDLYNPRD
                     TRDVIIGHILEDLDYAYTNILEEDVTHNSTIVNKWTAAAFKSRVCLFEAAWRKYHAAD
                     QLDIARTGCTEYSAKDLYKLAAEAAKEVMDNGPYKLYTSGAYSDGRGAYRELFIADKA
                     VTTEVMMAIETDKVLGLGEQNWWYNSSTYGPHLCMSRKFMLSYLNADGTPYVEKKADG
                     SYKNFVEETTGRDTRLNQTIRGADYTRKNASGVYEPTAANFTGHTLTGYQFTKFAMDD
                     VAYDDAATNDNDIPIMRYAEVLLNYAEAKAELGELTDADWAATIGALRSRAGITGGTP
                     QTGTLTTRPSSAEPYIASYYPTISDPSLLEIRRERGIELCLEGLRLNDLKRWNCCDLW
                     VNDPWEGIFIPSLNQPLDVNGDGNYDAYFYDTDKIADEKYAAIGVYVGTNKSNVLNVK
                     PVQGGYLMEYNYAGRSWPARQYLYPIPEVVIQFNTNLSQNPGW"
     gene            complement(16113..19676)
                     /locus_tag="ACZPB4_11805"
     CDS             complement(16113..19676)
                     /locus_tag="ACZPB4_11805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SusC/RagA family TonB-linked outer membrane
                     protein"
                     /protein_id="HIR1098930.1"
                     /translation="MSNFKHSFFRTLLYAQLLSGFSGVAIAAQISLSVKNRPMREVIK
                     ELEETTEYRFFYNDGIKGLNSPISVDVEDADINAVMDAIAKQANVAYVLKSGHQIVLS
                     SVKTVQQQGNKKVTGTITDPKGEPIIGANVVVKGSTNGTITDIDGHFSIEVTPNAILQ
                     VSYIGYVAQDVPVGNKDNLVISIHEDTQKLDEVVVVGYGSQKKVNLTGAVEQVTSDVF
                     EGRPTANATQMLEGVVPNLNISLSDGKPGRTADFNVRGAGSINGGSALVLIDGVEGDP
                     SMLNPNDIESISVLKDAAASAIYGARAPFGVVLITTKNATEGKPKVTWSSSYSLQSPQ
                     NVPDVVSDGYIWAKHFYDAYFNYNQANPSGINKTQQFSVAWLDEYKRRHETGDFGTVI
                     SDGSIGTKGRYVYYPEGTDYYDLMYKKSVFAQNQNLSISGSDGKFDYYLSGRFYSYDG
                     LFDSDEQTDKFKTYNMRFKGGYQLTPWLKISNNFEFSHNKYYNPITYSEGSGVVWRNI
                     ADEGHPSSPLFNPDGTMTYSAVYTVGDLLYGRSGITTKNSNLKNTTTFNAKFLGDRLR
                     VNGDFTYQQKTQEKTKKQVRSPYARSADANGESKIEYITGTYSNLAETTDHTNYLATN
                     LFAEFEETFAEKHYFKAMAGWNYEKSSFKRIYAYNDDLLTDDVDNMNLVMGTDNRSIT
                     SQWKAYQFGGAFFRLNYAFDNRYLLEVNGRYDGSSRFPSDERWAFFPSASVGWRISQE
                     PWWNVKSEHISNAKVRFSWGSLGNAAGLSNYQYIQTLGISKSDYILDGLRQNYMSSPA
                     ALPGNLTWETATTYDIGVDLGFFDNRLTVSGDYYIRKTTDMIVNGPTVPDVFGASSPK
                     GNYADMSTYGYELSLEWKDGFDLAGKRFNYSIKGTLADYYSVIDKFNNANMSLSEYAN
                     QSLDKNYYEGMRIGEIWGFVSNGLWQDQAGIDAAEAAAKAAGQSYYNPLMQTSKTYKL
                     YPGDIKFEDLNGNGYIDRGQNTVDDPGDRKIIGNEEPRYIYSFTLSADWNNIWVSAFF
                     QGVGKQDWYPSNEASTFWGQYNRPYNQMPSWHVDNYWTPENPDAFLPRYTGYYAPFYG
                     GHKNANTRYLMNAAYLRLKNIQVGYNLPSEWIKKLHLTNVGIYLSGENLFTWSPLYKY
                     SKDVNVSNIGESDKDLTSSNSGDGYNYPMMKSFSIGLNVTF"
     gene            complement(19901..20905)
                     /locus_tag="ACZPB4_11810"
     CDS             complement(19901..20905)
                     /locus_tag="ACZPB4_11810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecR family protein"
                     /protein_id="HIR1098931.1"
                     /translation="MRKMHTHIELLDRFMSGKTSPEEERTLLAWFRDPDHKEEIMAFY
                     KSRWEESSGKKLPPKLQGQMFCEIKKRMRQEKKTLEIKKKPHTLWKWLSYAAVALICI
                     GLGIGSHWYNMRQVPPPDPLDYVVLADNGQRASVVLPDGTKVWLNSHTKLNYKSDYGV
                     KERSVSLSGEAYFEVSKDTLRRFLVNAGDMEVEALGTAFNVKAYEEDDEVVTTLFEGS
                     VRTAVGKEFVILSPDESSVFNKSSHILSVNHPTNASYARLWRTNELAFSGESLEEIVV
                     LLNRMYNVEVRFLSNKIKGYSFSGVIRNNSLDNVFEIISLTAPITYVSVGDTIYLNEK
                     "
BASE COUNT         5835 a         5487 c         3834 g         5800 t
ORIGIN      
        1 tccacctttc ggtcataagt gaccaagccg tttatctcat gttccacatc tgtagtctgc
       61 gtatagatgg ccgtgcttag tccgaaatag tttatcatct gctctagctc ggtaagcatt
      121 aatacatagg tatcggtcaa gatttctcta ttcaacatca tctcataagc gtcattgcgt
      181 acaggccaca tatgcccacg cacaaataga ccttttcctc cgaattcgcc aagggacgca
      241 gcacgtttat catcgggacg ggggatcgcc ttaggctcga tcttgccata atgatgcata
      301 tccacgaaat ctccatttcc gggatctcca taagccttac gatagcccgg agcgtaatta
      361 tatcccgaca taccgtttac ccaacgattc ggatcgtact ttttcaccca agctgtgatg
      421 tctgtcgctt caaaggctcc ccaattctca ttaaacggga cccacatcac gatagaaggc
      481 gagctgacgt gttggtcgat catcactttc aattcgtcac ggaactgttt acgaaccgcc
      541 acggaatcct caccatcagg ctcccaaaga ttcggcatat cttgccaaac cattaggcca
      601 agcctgtcac aatgataata ccaacgttga ggctctactt tgatatgctt gcgtattaca
      661 ttaaaacccg cacgtttcgc cagttctata tcatacaaca aagccttgtc ggtaggagcg
      721 gtaaacgcgc catcgggcca ataaccctga tccaaaagac cgatatggaa aacaaactcc
      781 ccgttcaata aaggccgaag cacaccatct acctttccca tactaacaga acgcatacca
      841 aaataagagg atacctcatc gattatcttg ccctttcgat ctttcaactg taatttcaaa
      901 ccatacaaga aaggatcatc cggactccat agacggggtt cccggatagg caagtaaaaa
      961 ctcatattgg aatttccttc ggttcttgcc acctctgaag taccattatc cgcgatagcc
     1021 gttaccttta actccttatc ctccgtataa gcaattactt ccaaccgatt attttttaaa
     1081 tcgggaacaa gcttaatctg aaaaatatat tgtttctcta ccggttcaag ccaaacggtt
     1141 tgccagatac cggaagtaaa aatataatct ccacgtgagc cgttcttgcc cgaagcggcc
     1201 cggccgtcgt taggatcata agcacctacc acaaggacat tttcaccgga tttcaaataa
     1261 tcagtaatat ttaaactaaa agcatcgtac cctcccgtat gggtacccac cttcttaccg
     1321 ttgacaaaca cagacgagat ccgatctaca gccccaaaat tcaacaatac attcctgccc
     1381 ttccatgctt gaggaacaga gaagctacgc ttataccaca ggcaagtatc acccccacga
     1441 gctataccgg ataattccga ttccggagga tacggcacac gtatcttttc tactttcgcg
     1501 ggaaaggctg gaggagtggt cgccgtaaca ggatcgagca ggtcttttcc tcccatataa
     1561 tcccatatac cattcagatt caaccattcc gaacgcacca tctgtggacg cggatattcc
     1621 ggtaaaggaa tctcagcctt caatgcctcc tctgtccatg gagtaggcaa tgtgaacttc
     1681 tctaggattt gcgcctttac ggagaagaga tctcccccaa aaagaaagga gcaaagagct
     1741 aaacaaacaa cggtaatctt tttcataaac caactattta aataattccg gataatattt
     1801 ccgaatcaaa tcttgatctt ctttctccaa cttatcgatc aagaccggct tatcttgcgg
     1861 gcggagacct ttttggttga ttttgttgat caagctccaa tccttagccg gttttgtcgg
     1921 ggtcggatcg gcaggttcat gagccggcaa atcatagcgg gtaaagtcga tgacataagc
     1981 cggggaattt ttcgtatgcc aatcacgtaa taaggccaag cggaattcct tattcataaa
     2041 ccattttatc tccaaattat tataagagtc tcccaaacca gagccacgtt ctacgaagcg
     2101 atagttccag tcgtcgttcg atttatattg ttttctccaa agttcgccaa attctccgaa
     2161 cgtaacgaaa tgagtatccg gccagcgttc cttggtaccc gttacccaca tcttcatggc
     2221 atcacagatg agatccttcc cgaactcatg taccatctgc gcctcccaga tattggcgac
     2281 ccagccaaag ccattcaact caagaccttt atcaaagtga atcgcttccg tgtgcatcac
     2341 ctcacgatgc cccaagtcaa gcccccaacc tttgtacgtc tcgatcgggc cgacacctct
     2401 acggctgttg tatccatcga taccatgtcc ggtctgtccg ctacggcggg cacagataaa
     2461 gtccatcgtc cagccatcca gattcacgca atcgatgaaa tcgctttttc cctgcgccgg
     2521 cttgcagaag tgttccgtcg agggatagaa aggataagaa ggagaaccgt cagcaccacc
     2581 accgtctata ttatgctggc tccagatcac ggcgtgcgcc acatggatgt tctctttctc
     2641 cgccagatat cttagattat cggccgataa gaaacctccc ataatcgatt ggggacgata
     2701 accatttcct accattttag aaatgatctc tatcgcctcc gacatctcac ggtttacccg
     2761 ctcacggggt agatacatcg caggaaaata accggggaaa taagtaacct catccccata
     2821 tttcttttgg cactccacta cataatcacg gatctcccgg taattcttcc gtccgtcctc
     2881 caaggcattc atcgtgaatc cccatgtaag acgaccgttc gggttattcg tggcgaaagc
     2941 ctcccgcaag gcccgcactc cttcaagcgt atgccaatcc acctcatccc ggggatgcaa
     3001 cttgacatcc cgggagactt cccaaggcgt cgtacgtatc atgatacata aggtgacaaa
     3061 acgatttcct tctatcgtca gcggttccgt attcgccggg atgaccacag gatccgccgc
     3121 ccttaattga aaaccactga gcacagagac catccatacg atcgcccatt ttctccaaac
     3181 tgatatattc atattacttt ctcgcatttg tacaatctat tactatttcc tgatccgacg
     3241 gaaacatcct aaagacataa tccgaaccag attcaggttt ccttatatgg cctttttcgc
     3301 aagtgatcac gtagttgaaa ccatcgaagc tagcgttgac cgccttatcc tctataacgg
     3361 tgaaaggtag ctccttccct gccgcagcct ttagctctaa agcccatgag aagtccgcct
     3421 cctttgatag agcgactacc tcgaagcggg tctcatagaa cgtgatcttg aaagcatggc
     3481 cttttgagtc ttcggcggaa actaccaagg tatccttgcc tatctccgtc actaccggat
     3541 ggtccaagga aagttcctcc ttatctccat ccttgtctaa tcggacgatc cgaagcccgg
     3601 cacgatcgag tccctcgctc cacatgaatc cgtccacgac cggcaacgta tagaatagga
     3661 actggttccc gtctccgggc ttttctagat aagccgactt atagctctcg tcgaaaagat
     3721 ggatatccct aaagcggaat gttcccttct cccacaataa gttcgcccga taataacggc
     3781 tgttaaacca gaccgtctta ttgccttctc cacggacatc cgtcaacgta gtgacagccg
     3841 tcgccggcgt aaccttgaag cattccttga accacgcacc ggattcgccc agcgtctcca
     3901 cccggatctt attttccttc ctcaaggagt ccaaaatagg gatctgcatc tccagtccct
     3961 tgctcatatt actccacgtg aaagagttct cctgtcccgc ttgcgcgtaa ttgaaggcca
     4021 gacaaggctg gttcacgatc gattccaaga aataatccac ccagcgacga tccatgcccg
     4081 ccttctcata cacgggttcc aaggagatca ccccttgacg ctcttgtccc agaccatcat
     4141 catattgata aataggatca ctgcccagca tacggaaaat aggaacgggg atttgcccct
     4201 cctcggtctg cgccggcata taggcgttta cccggctcgg gtaataggct tggttccagt
     4261 aaccacccca tagggtataa ccatccgtcc ccacttggtc cttgcagttg cacgacgcca
     4321 cgatcttata tttatcgtac atatagccca aggtatgcgc gtcgataaac caagagccga
     4381 ccgatttcgg gtacgtgccg aatatctcct tgaacttcgc catatagaca tccaccagtc
     4441 gctcccgttc ttctttcgta tatccggtgc tgaaagcgat attcgcgtgc gagacccaag
     4501 aatgctcgcc acgccacttg atcccggcgg cctcgatctg cggttgcgta agttcccacc
     4561 aagcaccgat ctcggagtga gcattgagtt tacttttcaa cagatcttgg tacaacgggt
     4621 tgatcaacgc atcgtactgt aataaaaagg tagccggtaa atcatattta ttcaccaatt
     4681 tcacttgctc acaaaccgtc tcgtacaata agctatcggc gttctccacc cggtagtctg
     4741 tctggcggat gaaattgatg atgttgataa tacggggagc agccgcactc tcaaccagtt
     4801 tctctcccgc gctacggcat cccgcacagc agaagacgat aaagcataca agacctatct
     4861 tctttatgaa tgacattcga ttcaatttta aattcattta ctctcataaa atattctaga
     4921 aatggcattt cacaggtgta aaatcatttt tagaaatcta aaaggcattt cgcaagggtg
     4981 caaagccatt tcttaaatct aaaaacggca tttcacaagc gcaaagtcgt ttttagaaat
     5041 ctaaaaggta cttcgcgagg gtgaaaagcc atttcttaga tctaaaaagg cattttacac
     5101 cagtgcaagg ccatttttac cggaatataa ggcattaccc taccaccccg ggttgttcgg
     5161 agccaagttc gggttcagat acaactcatc caacggaagg gaataatagt aatgcttcgg
     5221 ggtcacaaag ttacgattct ccgccggttc cacaatcaag aaaccatttt cgtctgtcaa
     5281 accgggattt ccctcgttca agacatccaa gttctcgtat tccgaacctt tcagcttaat
     5341 accttttatg gcacctatca attccgtctc agccgtcttc caacgtctca aatcatccct
     5401 gcggaagcct tcgaacgcta actcgatcgt acgttcccga cggatctccg tccgcatatc
     5461 caacccattg ctcttcacga aagcgttggt caaaggaggc atctccacgc ctttccggga
     5521 acgaatcaca ttgatcgtct tgttcaagat gtcatcgctg atcgccccgt ctttctcgta
     5581 agtggcctca gccaatatca gcaatacctc cggataacgg atgatgtgat aatcatatac
     5641 atccttgtca gaaggaacgg aagtctccgc catatatttc cacaacttat aacccgtacg
     5701 tgtctcggga cgtatggtaa attgcggcgg gcaggtcaag gcgccgtctt gcggactgat
     5761 atagtcggtt ccgggcatca agaaggtctg tttcatacga gggtcacgat tctcgtattc
     5821 gctcttgatc gtggcatatc cctcaaatcc ggaattagcg ttctcaattg gcaatcccgt
     5881 actcttacac aaatacatat ctgccagctt acgggtaggc gtccctcgcc atccccaata
     5941 tacagggcac gcgtcgctat ggtggcggat atccgtctcg taccgactgt cgaagatacc
     6001 ttcttttgaa ttatcgcccg cattgataaa caagtagcgg tagctctcct caccagagcc
     6061 ttcatataaa gcatactcac cactatcgat cacttttgca gcggcatcga tcgcttgttg
     6121 caacaactgc tgatagtccg aacggtgctg gtgatacttc gcccacgtcc cggcaaacaa
     6181 ggcaaccctc gctttcaacg ccaaggcagc gccttgggtt acacgtcccg cctcatccga
     6241 gcttaactca ctttgcaagg gtagtttagc atacacctcg ttgagttccg acaagatgaa
     6301 gtcttccacc tcctgttgct tattcctaga accatacaac tccggggaat ctacggtaag
     6361 caccttcgtc aagataggaa tatcgttgta tttcgccatc aaccgaaaat gcgagtaagc
     6421 acggaagaaa cgggcctcag ccacataccg ctcgatctcc gagggatcgc cctcgtacgt
     6481 ctggctcttc tcgataatca tattgctctg acgcaggtct atgaaagtag agtcccatag
     6541 ggcatccgta ttcggggcga tcaacgtacc gttgctcgtc gtattctcgt tcaactcata
     6601 ggcgatatcg ctatccgtat ccttcgtgcc gaatgtctcg gtacgtgtgt agagccaatt
     6661 gacctctttc tcgaaatcat ccggggtttt ccagaatagc tcgtccggca tattatcttt
     6721 tggcaacagg tctatatctt ggcaacttga caagaacaaa gcggaaacaa taaagcttcc
     6781 caatattatc cgatagtttt tcatgacttt tcgctttaat ttttaaaata cgacatttat
     6841 accaaatgaa taattacggg taaacggata ggaagtaatg ctaccgctgt tctcctccgg
     6901 gtcccaacca tttggcgtgt tatgtacctc aaataaatcc tcgccggaaa aatacacccg
     6961 caccttctgc aaaccggcct tcgaggtcaa agtctgcggg atcgtataac cgaactgcaa
     7021 gtttttcaaa cgagcatacg caacgttaaa cttcgtgttc gtagatacat aataattgta
     7081 gtttcgttta tccttcaacg tgatcgccgg atactgggcg tccgttcttt ccggggtcca
     7141 agtctttcca taccaatact cggcggattg ataccatgcc tctggcatcg ggcaccgact
     7201 ctccccttcc aagaacatcg tcctacggcc gactccttgt atgaaagcac tcaaatcgaa
     7261 tcccttccaa gccatactca ggttaaagcc gaaattataa cgcgggttct tgtcgcccaa
     7321 gtatttcacg tcaccggagc cttctttacc atcacctaat acggatagct tcccgtctcc
     7381 atccaagtcc ttgtacatag cgtcacctac gctcaagtca cccgggatac ccccttccga
     7441 gaaacgagat ttatacgcct ccaattcttg ctcattctgg atgattccat caaattcata
     7501 tccgaaatag gaattcaacg gatatccggt cggagtctcg ttattaccta atttgatcag
     7561 gttacttcca acccgatcca cgaccttgtt tttcgcgtca ctgatattaa agcgaaccga
     7621 gtagctgaaa tccttgatct gatccctcca gcctagagag atttcccatc catgaatact
     7681 taaatggccg ctgttcgtgc tcggagcgtc cgcacctaac atagaaggat aggtcttcgg
     7741 gataagcatg tttttattct ctttccagaa gtagtcgaac gatccatata aacggttatt
     7801 gagcgtcgag aaatcaaatc ccacattggt tgtctggatc gtctcccatg tacgagaggt
     7861 agaaataata tttccagacg tagccatttg tcctttcacg ccagtcccga aaggataata
     7921 atcgttcgat aaagagatca attgaatata atcatacaat ccgataccgg actgattacc
     7981 catctctccg taagaagccc ttaccttcaa gtcctcgaac caacccaatc ttttcatgaa
     8041 gccttcttcc ccgacacgcc aagccgcgtt tacacccggg aaccatcccc aacggtgatc
     8101 cggatcaaaa cgggaactac catccgcacg gatcgttcct tcgatgacat atttattggc
     8161 aaacgtataa ttcactcttg agaagaaaga attaatcgtc cactgatttc cctcgctcca
     8221 agcgttttga tcttgggcgc tacccaattg caaagacata ttttcttgtt ggtcgaagtt
     8281 aatacgcttc gccgtgaacc tatcatagtt ctcagactca tgggaagtac cgaccatcac
     8341 gcttaaatca tgccggtcat tgaagttctt tttataatca gcatagagcg tgaagttctt
     8401 ggataaagtt ttctggtaac gacgctccgc actattcggc gtacgtttct cccggacctc
     8461 gttattatcc caatcgtaat tggtgatttt cttgttcgtc acgttctcat cctgatcata
     8521 cttacggatc acggcttgcc ccaccaattg taatccgtcg atcactttcc agcgtaattg
     8581 gttgttgacc gttatattac ctgtagtctt attcaccata cccccgtctt ccaatacttg
     8641 agccggatta tcgaaaccct cgaatgtata gaaagttccc gacggattgt acatcggagt
     8701 ccaagagcga gtcttataaa tcagttccca tatattttgt ccttccgtca aacccgagga
     8761 atagtccctg ttgcttgcct cataagctaa attaagatcg taagtcaagt tcttgaagat
     8821 ctcgacgctc gatttagcac gtacgaagta acgcttgttc acatcctcac caaatttagg
     8881 gataccttcc tcccgctgat ggcctaaaga caacatatac gagtatctct ctccaccgcc
     8941 ggagatattg acattgtaat tctgcatatt accattgcca ataagcatat cattccagtc
     9001 ttgatccttg aagaattgcg gataaccggt ccaacgcccc cattccgcat cagtcaacac
     9061 cagatcacta ttctgccgga tcaggtccaa ttgatctctc gtgtattctg gagtgaatga
     9121 tccatcggtg atctccaagg ccatctccgc atgttgtaat agattcgccg gtttccttaa
     9181 caacgcagga gtcttaatag agtaatatgc atcaaaagca acagatgtct tctgattgcg
     9241 cttaccactt ttcgttgtca ccagaataac accatccgag gcacgagcac cgtaaatagc
     9301 ggccgtacca tctttcaata cggaaatatt ctcgatatcg gaaggattga tcatattaat
     9361 gtttccctcc gctccatcaa tcaaaacaag gggagtacca ccgttgatag aagagacatc
     9421 acgaaccttc atggtcatgt ccgaacccgg agcgcctccg gcacgtgtaa tcgtcaaacc
     9481 gggtacctct ccctgcaaag cctgagccgc attctgaatc ggacgagatt caaacgcttt
     9541 cgcgtcggcc ctagatacgg caccacccaa gttcgctctt tttaccgtac cataaccgac
     9601 aactacaacc tcatccattt gcaaagcatc ttcccgtaac ttcacgttca aattcgcttc
     9661 cttgccggga cgcaattccg tcatggcata tccgatgtaa gagatttgaa ggacaccgtt
     9721 ttccgatacc tccatcgtaa attttccatc aaggtccgta accgttccgt tggtagtacc
     9781 tttctcaact acgttcgcac cgataatagg ttctccattc tcgtcggtca ctacaccttg
     9841 cactaaattc ttcttttgca aaacggcttg tgaggaaggg gcggctttct cgttttttgt
     9901 agagggatta atcaagatga aattattctc cgtaatctca tactttacgc cttcccctgc
     9961 gaaaagacgc tttaaaatgg tttccaccgt ctgctctttc acatgtacag atactttctt
    10021 attcaggtta accttctcgc tctcgtagat aaaacggaag ccagactgtt tctctatctt
    10081 gaaaagaacc tcctttattg tctggttatt aacgtccaaa gacaactttg tctcttgcga
    10141 atagacagag gccgagatct gaagtgaaca tgcgatagag aataatgtcg tcaatctcat
    10201 aatagacaaa gtttttttaa ggaccggaga ctcttccggc cttgctatat tccaaaaatt
    10261 catatatttg taattcgatt gtttgttaac actagtgtta cgagcactaa ttttaatgat
    10321 caaaaagatg acggggaatg ttccagcatt tcccgttttt catgtgtatt catgcgattc
    10381 ctgttcttta cttcataggc agactttatt tagaggttat acttatattt tttcctttca
    10441 cgttataact tatatcactc aatcgggata gtacgcccaa tatatccgtt atggtttcct
    10501 cctgtatgac tccatcgtaa tgtatactat tccccaaatc cttttgaaga tggatggtta
    10561 catcgtacct cctctccaga tatttgcaga cggaagccaa cgacatatga tccatataga
    10621 gtttatcctc cagccagctg tacgaatgag ataacacacc cgatatcggt ctcatcttgt
    10681 tggtttgctt atcgaaaatc gccatgtcac cggcgttcat taacaactta tcattcccat
    10741 gatccaactc gatacagcct tccaccaacg aggcttcaac tgttttttca tccgtatacg
    10801 cttgcaaatt aaaagaagtt ccatgtacct ttaagcgtaa tccattgctc atcttgatca
    10861 cgaacggtat cttgttcttc gagacatcga agaagccctc tccttggaaa ttcacttccc
    10921 tgatattctc ctttgcgtta taggaatacg taatatcaga tccagaattc agcttaacaa
    10981 cggaaccatc cggcaagacc acctccgatc ggcttccgta atcagcggtc attcgaacca
    11041 gcatttccgg ctgtttatca aatactccca ttttcgaaaa cccgaggaca agcaataaag
    11101 tagccgccac tcctgaaatg atatatccga tattcaccaa gcgtttccgc ttattatctc
    11161 tctccttatt gatacgatcg atcttatccc atgcgtattg agcattaaaa gtttcttgct
    11221 ccagataaga gcctgtttct ttccagatct ctttataccg tttaaaatcc tcttgattag
    11281 actcatcctc agccaaccat tcatccagaa ccggatccac gatctcttca ttcatcctct
    11341 ccgataaatg gtcaacgatg tgttctccta tttgcttttt cttctccatg agtctagtct
    11401 ttatttaaat gacaccacaa ataaaaaaag gtcctatacg aaccttgaaa attttctcat
    11461 tattttatac ctccttcatc tccagacatt ccttcaactt ctgtaaagac atccatattt
    11521 gatttttaat tgttttcacg gatatagata gtttctccga tatttctttc tgcttcaatc
    11581 cttttaccct gtgaagaagt aacacttctc tactccgatc cggcaaatgg tctatacaat
    11641 cataaagagc gatcctaaac tcttctgttt ccagttgatt atcctcatag gatagaagta
    11701 ataagtcttg attctctgat aaacttcccg tctgcacctt tgatcggata aagttcaagg
    11761 ccagatgttt agccatccga tataaatatc ctgatacatt ttcctttatc tctattctcc
    11821 ccctattttt ccataaattc aagaaaagct cttgaacaac atcctccgca tcatttctat
    11881 ccatcaatag actatacaca tactgacaaa gacgcccgta ataacgatca aacagtttat
    11941 tataactgat ataatcatta tttccgatcg ctagcattaa gaccttatcg gcatgaactt
    12001 cctgcatata atcttcattt atcatgaata ttcacaatcg tctttacagg taaaagagtt
    12061 tcggcaagac tatggctaac aaaaagaaga acgaagatat aaagcgaaca aattcagttt
    12121 gtaaccgaag tttaaaaaga tgcttagtaa agagatctga gatttcagga aaaggagaac
    12181 tggattataa atatatgtgg tagaataatt tacagtttat caacaaaacc atagtcttgc
    12241 cgagactcag ttgaaataga tctcagaagg atattttaca agaaattaat cctgcctttc
    12301 cacaaatctc ctgtgacgca aaagtaggaa aattattatt tgattgatta ttttatcatt
    12361 cttttcatat aagatcatct tcccttttac tccccagcaa ataaaaaggg aaatatctca
    12421 cgacacttcc cttttaccat gaatcttatg tttgaattat tttacttcta ctacaatcat
    12481 cacagggaaa tgatcagatg gaacacgagc tacatgtttt tgcatggaga cctccttcgg
    12541 aaaattcgca ttttgctcat tcttcgcatc tttcgcttcc gaacgatatg tatccgtcaa
    12601 gacaccatat tttttcacat caaactcttt cgtaaggaat aaatgatcga tacgactgtc
    12661 tgttttgcga tccgcatgga aggcattaaa cgtgccgttg ggtacatacc ggaaatccgc
    12721 tatctgataa gaatcccgca taataccgga attgtccagt aataagtagg attcattatg
    12781 ttgatccaca ttaaaatcac ctgttagaat cgccggtagc ttctccggaa attctttcaa
    12841 cttcttaagg ataagtttcg cgctttccgc acgggcctgt acaccaatat gatccatatg
    12901 taagttaaag aacaagaaag taaagccggt ttgtttatcc cgaaatttac cccatgtgca
    12961 aatacgggga agaacggcat cccatccctt attagggcga tcggttatcg tagacaacca
    13021 aaagtcccca tgatcgagca cctcgaactt tcccgtacga taaaatatgg cagaatattc
    13081 accagcttgc ttaccatcat cacgtcctac cccgatataa tcataaccgg gcatcgcatt
    13141 ctttagatct tgcaactgat gatatttacc ttcttgagtc ccaaagatat caaaaccatg
    13201 gaactgcacc aattgggcaa tgtagggata acgttgtccc cagccattcc cattcgtcga
    13261 gtctcccgca ttcgcattac gcaaattata ggtggctact accattgact ccgcttgtaa
    13321 cgcaaatacg gaacaaagga caaataaaaa agaataaatt agcttcttca taccttttat
    13381 cataaaatta aatccacatc aataaattag aactctgcct ctatcattat cgggaaatga
    13441 tccgaagaga aatgcccata ctggcactcg ttcaaagtcc catatttatt tacctgaata
    13501 cctttagtga cgaaaatata gtcaatccgg tttttcatcg gggcattcaa attgaattgg
    13561 tttgtcgttc ctaccgtccc atagggtggt gtttttgaga tttcccgtga gtccaacagt
    13621 aaaccatcgg atttcagtat ttgtataggc tcagaatccg gcgtaccatt gaaatcacct
    13681 acacagatag caggggaatc ccccgctatc tttttaatat tagccaacat tatcaaagca
    13741 gactcatgac gtgccacctt accgatatgg tcaaaatgaa cgctgaagaa ataaaattcc
    13801 tttcccgaaa ccttatcctt caacttcgcc caagaacaaa ccctccggca ttgcgcatcc
    13861 cagccaaaag aaggcttatc ctgtgtctcc gacagccagt aatttcccga gtccaataat
    13921 ttaaaccgat ctttcttaaa taaaaccgcg gcatgttccc cagcctcttt tccgtcatcc
    13981 cggcctacgc cgacatacgt gtacgtatca tctttcacta attccttcac ttggtgaatc
    14041 aacccttctt gaatcccaaa gacatcaaaa tcatggaaat gaaccaaaga taccgccatg
    14101 tctttgcggt gtacccatga atcatcctta tccccctcat tatcataccg caggttaaaa
    14161 ctacccacgt tcagtttaca cttctgttgt ccggatatcc ctatgcagaa agtaaataaa
    14221 gagataaaca ctataattaa gtttctcatg ataccccctt gattaccagc ccggattctg
    14281 gcttagattc gtattgaact gaattactac ctccggtatc ggatataagt actgacgagc
    14341 cggccagcta cgtccggcgt aattatactc catcaaataa cctccttgaa ccggcttcac
    14401 gttaagcaca ttactcttat ttgtacccac atagacacca atcgcagcat acttctcatc
    14461 agcgatctta tccgtatcat agaaataggc atcataatta ccatcgccat tcacatccaa
    14521 cggttggtta agtgatggga taaagatacc ttcccaagga tcgttcaccc aaagatcgca
    14581 acaattccaa cgtttcaaat catttaggcg caaaccttcc agacaaagtt caataccacg
    14641 ttcgcgacgg atctccaaca aggaaggatc agagatcgtc gggtaataag aagcgatata
    14701 aggctctgcg gatgacggac gggttgtcaa tgtacctgtc tgtggtgtgc ctcccgtaat
    14761 tcccgcacga gaacgaagcg cacctatcgt agccgcccaa tccgcatcag tcagttcgcc
    14821 taattcagcc ttagcctcag catagttcaa caaaacctca gcatagcgca tgataggaat
    14881 gtcattatca ttcgtagccg catcatcgta agccacgtca tccatggcaa acttcgtaaa
    14941 ctgatatccc gtcaatgtat gtcccgtaaa attagccgca gtcggctcat aaacaccaga
    15001 agcattctta cgggtataat ccgctccccg gatcgtctgg ttcaagcggg tatcacgtcc
    15061 tgttgtctcc tccacgaaat tcttatagct tccatccgct tttttctcga cataaggcgt
    15121 accatccgca ttcaagtatg acagcataaa tttacggctc atgcataagt gtggtccgta
    15181 agtagaggaa ttataccacc aattctgctc acccagtcct aacaccttgt cagtctcgat
    15241 agccatcatt acctccgtgg taacggcctt atcggcaatg aaaagttcgc gatacgctcc
    15301 acggccatcg ctataagcac ccgaagtata aagtttgtac ggtccgttat ccataacttc
    15361 cttagccgcc tcagccgcta gtttatataa atctttggcc gaatattccg tacatcccgt
    15421 acgagcgata tccaattggt cagcggcatg gtatttacgc caagcagcct caaacaagca
    15481 aacacgagat ttgaaagcgg cagctgtcca tttatttacg atcgttgaat tatgcgtgac
    15541 atcctcttcc aatatattcg tatacgcata atccaaatcc tccaagatat gcccgataat
    15601 cacatcacgt gtatcacgcg ggttataaag atccgggtct tcagcctcgt taaatacctt
    15661 atcaatccaa ggtacctcgc catattgtac caatttatca aaatagaagc gagcacggaa
    15721 caagcgtgcg ataccattat aattgtcacg gatagtcgtg cttagtgact cattcacgtt
    15781 attctccaaa aagaaattta tattacgaag agcggaccat gaccaactcg tcgcgctatt
    15841 cgtagtataa gcgccaacct ccataccacc caaggaattt ttcaccccat aatctgccgt
    15901 agcatcacgc cggaaagcgc ttcctcggga aggcaagaca ttgtaaaatg agtacgtata
    15961 cgtcttcaaa ccattctcgg agctaaacac catatccaca gaagcctccg actttggttc
    16021 ctcattcatc tcgcaccccg aaaatatagc caaaagtgcc accagaccgc ttaataatat
    16081 attctttttc atttcgtata atctcctatt ctttaaaatg taacattcag gccgatgctg
    16141 aacgacttca tcatcgggta attatatcca tcaccactgt tgctggaagt caagtcctta
    16201 tccgattcac cgatattcga tacattgaca tccttggaat atttgtaaag cggagaccat
    16261 gtaaagagat tttccccgga aagataaatt cctacatttg tcaaatgcaa cttcttaatc
    16321 cattctgatg gcaaattata gccaacctgt atgttcttca agcgtagata ggccgcattc
    16381 atcaaatagc gcgtgttggc gttcttatga cctccataga aaggcgcata gtaacccgtg
    16441 taacgaggca agaaagcatc cggattctct ggagtccaat agttgtccac atgccaagag
    16501 ggcatctggt tatacggacg attgtactgc ccccagaacg tagaggcttc attagacgga
    16561 taccaatctt gcttacccac cccttggaag aaagcactta cccagatatt gttccaatcg
    16621 gcagagagcg taaaactata aatataacga ggctcctcgt taccaatgat cttacggtcg
    16681 cccggatcat ctaccgtatt ctgtccgcgg tcaatatagc cgttgccatt caagtcttcg
    16741 aacttaatat cgcccggata caacttatag gttttcgatg tttgcataag tgggttataa
    16801 taggattgcc ccgcagcttt cgcagcggcc tcagccgcat cgatgccagc ttgatcctgc
    16861 cacaagccat tggatacaaa cccccaaatc tcaccgatac gcattccctc gtaataattc
    16921 ttgtcgagcg actgatttgc gtactcgctc aatgacatat tcgcgttatt aaacttgtcg
    16981 atcactgaat agtaatccgc caatgttccc ttgatactat aattaaaccg cttaccagct
    17041 aaatcaaatc catctttcca ttccaaagac aactcataac cataggtaga catatccgca
    17101 taattacctt tcggcgagga agcaccgaac acatccggta cggtcgggcc attcacgatc
    17161 atgtcggttg ttttacggat ataataatct ccgctcacgg tcaaacgatt gtcgaagaat
    17221 cccaaatcca ctccgatatc atacgtcgtg gcggtttccc acgtcaagtt gccgggaaga
    17281 gccgccggag atgacatata attctgccgt aaaccgtcaa gaatataatc agacttgctg
    17341 atacccaatg tctggatata ctgataatta ctcaatccgg ccgcattgcc caaagagccc
    17401 caagaaaacc ggaccttagc gttagagata tgttcggact taacattcca ccaaggttct
    17461 tgcgagattc gccaacccac ggaagccgag gggaagaaag cccaacgctc atcactcggg
    17521 aagcgggagg aaccatcgta acgtccgttt acctccaata ggtagcgatt gtcaaaggca
    17581 taattcaaac ggaagaaagc gccaccaaac tgataagcct tccattgtga ggtaatgctc
    17641 cggttatcag tacccatcac cagattcatg ttgtccacgt catccgtcaa caggtcatca
    17701 ttataagcat agatacgttt gaagctagat ttctcgtaat tccatccagc catagcctta
    17761 aaataatgtt tctcggcaaa ggtttcctca aactccgcga aaaggttcgt agctagatag
    17821 ttcgtatgat cagttgtctc cgccaagttg gagtaagtac ccgtgatata ttcgatctta
    17881 ctttcgccat tcgcatcggc cgaccgcgca tatggcgaac gcacctgttt cttagtcttc
    17941 tcttgcgtct tctgttgata agtaaaatca ccattcacac gcaaacggtc acccaagaac
    18001 ttcgcattga atgtcgtagt attcttcaag ttggagttct ttgtcgtaat accgctacgt
    18061 ccataaagca aatcgcctac ggtatagacg gcagaataag tcatcgtacc atcagggttg
    18121 aacagtggcg atgacgggtg tccctcgtcc gcaatatttc tccataccac accagaacct
    18181 tccgaatagg taatcggatt gtagtattta ttatgggaaa actcaaagtt attgctgatc
    18241 ttcaaccaag gagtcaactg ataacctcct ttgaagcgca tattataggt cttgaactta
    18301 tccgtttgct catcgctatc gaaaagtcca tcgtaactat agaaacgtcc tgacaaataa
    18361 taatcaaact tcccgtcgga acccgagatg gaaagatttt gattctgcgc aaagacactc
    18421 ttcttataca tcagatcata atagtcggtt ccttccggat aatatacata acggcctttt
    18481 gtaccgatag agccatcaga gatcaccgtc ccgaaatcgc ccgtctcatg acggcgctta
    18541 tactcgtcca gccaagccac ggaaaattgc tgtgtcttgt tgataccaga aggattcgct
    18601 tgattgtaat taaaataagc gtcataaaaa tgctttgccc aaatataacc atcggaaact
    18661 acatccggca cattctgtgg tgattgtaat gaatagctag aagaccatgt caccttcggc
    18721 ttaccttccg tagcgttctt cgtcgtgatc aaaaccacgc caaatggagc acgtgcgcca
    18781 taaatagcgg aagcggcagc atccttcaat acggaaatac tctcaatatc attcggattt
    18841 aacatagaag ggtctccttc cacaccatca atcaacacca aagcactacc cccattgata
    18901 gaaccggcac cacgtacgtt aaaatccgcc gtacgccccg gtttaccatc agacaaggaa
    18961 atattcaagt tcgggacaac tccttctagc atctgagtag cgttagccgt aggacgcccc
    19021 tcgaatacat cactagtcac ttgctctacc gcaccagtca aattcacttt tttctgggaa
    19081 ccataaccca ccacgactac ctcatccagc ttctgcgtgt cctcatgaat agatataacc
    19141 aaattatctt tattgcctac cggaacatct tgagccacat aaccaatata agaaacctga
    19201 agtatcgcat tcggagttac ctcaatagag aaatgaccat ctatatccgt gatggtacca
    19261 ttggtagatc ctttcacgac cacattcgcc ccgatgattg gttccccttt cgggtctgta
    19321 atcgtaccgg taactttctt attaccttgt tgctgaacag tttttaccga tgataaaacg
    19381 atctgatgac ccgatttcaa tacataagcc acattcgctt gctttgctat cgcatccatt
    19441 acagcattaa tatccgcatc ttccacgtca acagagatcg gagaattcag acctttgatc
    19501 ccatcattat agaaaaaacg atattcagtc gtttcctcta attctttaat aacctcccgc
    19561 atcggtctat tctttaccga caacgatatc tgggcggcaa tcgcaactcc ggaaaagccc
    19621 gacaataatt gggcatacaa aagtgtccgg aaaaaagagt gcttgaaatt actcattttt
    19681 aaaagttttt taataataca tagattttaa acaggtaact ttacaagcaa atcatttaca
    19741 tattctatct tatttataac cggctagtta tttccttgaa gatattatat acaagtgatt
    19801 ttgcttaaga ggaagaaggg ccttgccttt cttctttttt tactacaatc atctagctca
    19861 tctcataggc ttcttcttta ttaggttaac actcaacttt ctatttctca tttaaataaa
    19921 tagtatcacc taccgacaca tacgtaatcg gagccgtaag gcttattatt tcaaatacat
    19981 tatccagact attattccgg atcacccccg agaaactgta gcctttaatc ttattggaca
    20041 aaaaacgaac ttcaacatta tacattcgat tcaacaatac cacgatctcc tccaacgact
    20101 cgccagagaa ggccagttca ttcgtacgcc aaagacgggc ataagaagca tttgtcgggt
    20161 gattaacaga taatatatga ctagacttat taaaaaccga actctcatcc ggagacagaa
    20221 tcacaaactc ttttccaacc gctgttcgta cactgccttc aaacaaggtc gtaaccacct
    20281 cgtcatcttc ctcatacgcc ttcacattaa aagctgtgcc tagcgcctcg acttccatat
    20341 cccccgcatt taccaagaaa cggcgcaatg tatctttcga aacttcaaaa taagcctcac
    20401 cagataaaga aactgatctt tctttcacgc cataatcact cttataatta agtttagtat
    20461 gcgaatttaa ccatactttc gtcccatcag gaagaaccac gctagcacgt tgcccattat
    20521 ctgccaacac cacataatcc aatggatcag gtggtggaac ctgtctcata ttataccaat
    20581 gggagccaat tccaaggcct atacatatta aagccaccgc cgcataagaa agccacttcc
    20641 ataaggtatg cggtttcttc tttatctcca gagttttttt ctcttgtctc atccgctttt
    20701 taatctcaca aaacatctgt ccttgtagct taggaggaag ctttttcccg gaagattctt
    20761 cccatctaga cttataaaaa gccatgatct cttccttatg atcgggatct ctaaaccacg
    20821 ccaaaagagt tcgctcttct tccggtgaag tcttaccact catgaagcga tccaataatt
    20881 cgatatgtgt atgcattttt ctcatcgtgt aataagtata tcccgaaaaa gaactttacc
    20941 cttacacgga aaaatc
//
LOCUS       DBMDTB010000073        20757 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_856_length_20757_cov_12.968242, whole genome shotgun sequence.
ACCESSION   DBMDTB010000073 DBMDTB010000000
VERSION     DBMDTB010000073.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 20757)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 20757)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20757
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_856_length_20757_cov_12.968242"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..1529)
                     /locus_tag="ACZPB4_11815"
     CDS             complement(<1..1529)
                     /locus_tag="ACZPB4_11815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HIR1098932.1"
                     /translation="MKLLSKYIFSALFLAASGGSATAQSMRANTYCNPLNVDYTYMIY
                     NSSNNLSYRSGADPAVVEFRGEYYMFVTRSHGYWHSKDLLNWDFITPGKNWYPQGSNA
                     PAAHNYKDSVLYVMGDPSGSMSVLYTDDPKLGNWNATPAILHDLQDPDLFIDDDGQAY
                     LFWGSSNVYPLRGKKLNKDDRFLIEGETVELFGLDMPKHGWERFGENHTDTVLGGYME
                     GAWLTKHDGKYYMQYAAPGTEFNVYADGVYVADSPLGPYKYQSHNPVSYKPGGFMNGA
                     GHGSTLVGPGGNYWHFASMSLSATVNWERRLCMYPTFFDKEGIMYCDNNFGDYPHYAP
                     AEPGKKGEFTGWMLLSYKKPVKASSYAEGSAPAAQGFTESNRPKTSANFLPANLTDEE
                     CKTFWMARTNGDTEWVEIDLEAPATVYAVQVNYHDHQSNMYGRIPGLRHRYAVEGSLD
                     GQDWVTLVDRRNNYKDVPNDYVQVDNPARVRYVRYKNIEVPTPHLAISDLRVFGIGEG
                     K"
     gene            complement(1548..3824)
                     /gene="bglX"
                     /locus_tag="ACZPB4_11820"
     CDS             complement(1548..3824)
                     /gene="bglX"
                     /locus_tag="ACZPB4_11820"
                     /EC_number="3.2.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucosidase BglX"
                     /protein_id="HIR1098933.1"
                     /translation="MKRLTTFIAGAAVAATLGGCQQPAVSGWKSFSGDKNIERRVDSV
                     LQLMTLEEKVGQMAQYSCNWDVTGPVMTGDYETLLKQGLVGSLFNVYTVDGVRKMQEM
                     ALSESRLKIPVLFGYDVVHGYRTIFPMPLAESCSWDLERMRKSAAIAADEASASGIAW
                     TFAPMVDISRDARWGRVMEGAGEDPYLGSLIAKARVEGFQGGNDWRSLADVNTVLACC
                     KHFAAYGAAEAGRDYNTSELSQNTLMNYYMPPYLAAKEAGVATFMASFNEINGVPSTG
                     NKWLMTDLLRKDWGFNGFVVTDYTGINEMVAHSIVRNDKEAGELAANAGIDMDMTGGI
                     YSQYLVQSVKEGKVSEENIDRAVASILEMKFLLGLFDDPYRYLDNEREKNTIMKPEFL
                     QEARETSARSIVLLKNDNNFFPISKDKNITVALIGPMVKDKINQNGEWAGRGEREESI
                     SLFEGLTEKYAGTNVKFIYAEGCDLLTDDSSKFAEAIATARRADIVLAAMGEDFNWSG
                     EAACRTDLKLPGAQQALLKELKKTGKPLGLILVNGRPLDLSWEDQHVDGILEAWYLGT
                     MAGHGMADVISGDYNPSARLTMSFPRTVGQLPLYYNQKPTGRPVPPEAPDTDYKSRYM
                     DVPNTPLYPFGYGLSYTTFAVNSMKLDQNSFTKGGKITVMAEVENTGKVDGETVVQMY
                     IRDLAGSVTRPVKELKGFEKVTLKAGEKKQVSFTIDEALLAFYGIDMQKKAEPGDFTV
                     WVGLNSADEANQSSFSLR"
     gene            complement(3839..6094)
                     /gene="bglX"
                     /locus_tag="ACZPB4_11825"
     CDS             complement(3839..6094)
                     /gene="bglX"
                     /locus_tag="ACZPB4_11825"
                     /EC_number="3.2.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucosidase BglX"
                     /protein_id="HIR1098934.1"
                     /translation="MRKIILSFAACLALAAYGQKPVQDTRAMDTFIDQLMGKMTLDEK
                     IGQLNLSGGGVPGILSGSEGADETIRRGWLGATGGSELETFRKLQEIAVKESRLGIPL
                     LFGLDVIHGYHTIFPIPLALSCSWDTTLIEQSARIAAIEASSNGVTWTYSPMVDIARD
                     ARWGRIAEGSGEDPWWGGKIAAAMVRGYQGDDLTKENTILSCLKHFALYGASEAGRDY
                     NTVDMSRIKMFNEYFPPYKAAVEAGCATVMSSFNLVEAIPATGNRWLLTDLLRDQWGF
                     NGFVVSDYNSIGEMTNHGLGDTQTVSALALHAGLDMDMMTNGYITTLKKSLEEGRVSQ
                     ADIDQACRRVLEAKYKLGLFEDPYRYLDADRAKKNTFTDEHMNTARHIAGKSIVLLKN
                     DKGLLPLRKTGTIAVVGPLADKKVELFGTWCGIDTAKSASVVQAVKEVVGNKARVIFA
                     KGCNLTNEPMLAKASGLKVDPVENTRLVKEAVEQVKDADRIIAVMGEPNNWSGEACSR
                     ADISLPESQKELLRALLETGKPVVLVLANGRPLTLEWEDNQFSAIVEAWHGGSAAACG
                     LVDVLFGDVNPSGKLTTTFPRSVGQIPLYYNAKKTGRPMNPDDHFTSKYLDITNDPLY
                     PFGYGLSYTTFSYGDLQLDKTSVQGENGVLTASVQVTNTGKLEGEEVVQLYIGDPAAS
                     ISRPMKELKNFQKISLKPGESRKVSFTITPEDLKFYNSALEYIWEPGLFNIYVGTNSR
                     DVKSAQVTWNK"
     gene            complement(6107..7501)
                     /locus_tag="ACZPB4_11830"
     CDS             complement(6107..7501)
                     /locus_tag="ACZPB4_11830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010182603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucoamylase family protein"
                     /protein_id="HIR1098935.1"
                     /translation="MYISMNTYFRTGVVTLLLGFSLTACHEAKKSDTSAESTANERKL
                     DFQSDDEFLTYIQKAHFNYMWEGAEPTSGLACERIHTDGVYPENDADIVTTGGSGFGI
                     AGLLVGIERGFITREEGVARFHQIADYLAKADRFHGVWPHWMHGPTGKVKPFGQKDNG
                     GDLVESAFLMQGLLCVRQYFKDGNESEKALAAKIDQLWREMEWTWYLNGQDVLYWHWS
                     PNYAWEMNFPLEGYNECLITYILAASSPTYPIPASAYHNGWARKGGIKSDAVAYDLPL
                     ILKHNYAEEYGGPLFWAHYSYIGLCPVGLSDRYANYWDLNRNHVLIDYRYCAENPKGF
                     KGYSDACWGLTASYSVKGYNAHMPSNDHGVITPTAALSSYPYTPEESSKALKHFYFNL
                     GDSIWGKYGFYDAFSEGENWYPRRYLAIDQCTITPMIENYRTGLLWRLFMSCPEIQDG
                     LKKLGFTIHNARES"
     gene            complement(7511..9667)
                     /locus_tag="ACZPB4_11835"
     CDS             complement(7511..9667)
                     /locus_tag="ACZPB4_11835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009016765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HIR1098936.1"
                     /translation="MFFRKDVGVSSASLKAYNKCMLVSLLASFFAVSTVNAQVNERGD
                     SVIVIKGQVSDYYITVSPEHFLEGTITGPDGKPLEGATVMFTASPVHYTTDATGYYKI
                     QASRYDHELFVYYPGMKYAYRTFGDNDTKIDIRMEADPRDVRVKAPQQATRWFDATAD
                     HPSTYCNPMNLSYCFRANLPDLVKNGSFRSTADPMMVMYKGEYFLFATNQAGFYYSKD
                     LSNWEFVFAGFQRYPEDDDLCAPAAFVSGDTLFYTGSTYAGLPIWYSTNPKSGKFKRY
                     VEKTALPSWDPAFLLDDDGRLYMYYGSSNEFALKGVELDRRDFHPISKIQEIMMLRPE
                     EHGWERFGMNNDDSTTLAPFTEGAFVTKHNGKYYFQYGAPGTEFKVYADGVYVSDKPM
                     GPFTYQKHNPMSYKPGGFVQGAGHGGTFEDAYGNYWHVATCMLSLKYKFERRIGLYPT
                     AFDKDGVMYSNTAFGDYPLLTPKGKVDDIANTFSGWMLLSYGKPVMASSMDSTLVPEN
                     VTDESMRTFWSARSGEPGEWLQISLEGLKEVRAIQLNYYEHRAVQHNKAMDLYHQYRI
                     YHSIDGQNWELVVDKSDNDKDVPHDYIELREPLKTRYLKIVNEHVPSGNFAMSGFRIF
                     GNGLGEAPAAVKNLKVERSKADKRNAMITWEPVKEAYAYNIYYGIAPDKLYNSITVLG
                     DTMYDFRGLDKDTDYYFSIEALGESGRSPMSKVLRR"
     gene            complement(9808..11973)
                     /locus_tag="ACZPB4_11840"
     CDS             complement(9808..11973)
                     /locus_tag="ACZPB4_11840"
                     /EC_number="3.2.1.214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exo beta-1,2-glucooligosaccharide
                     sophorohydrolase"
                     /protein_id="HIR1098937.1"
                     /translation="MKHIALLTTLLLSASLQAVEKPYDYVFFENSLMKGDYFYSQAKY
                     TSPSWIKNARHHLPVAGSVAFTPGNSLELTYVSAPGGDWYSEIQYCPVRGNDFFREPS
                     TLSMQVRLRESMNAAALPNIAIRYADSTYTQYLNLRNYLKDTRPGVWHSVSIPLEDFG
                     LNAVNDTNIKKLAAVALRPGTADGNEYTIYLDDIELLPASLPSVSALNAPVLQEAKAY
                     ERHIDIKWIPQSKEDIKYYRIYRSFDGVTYQPVAIRRPWMNRYTDFLGEVGKKAYYKV
                     TAVDYALNESNDSQTVSATTYPMTDEQLLDMVQEANFRYYWEGAEPNSGLARENIPGR
                     NDMIATGASGFGIMAIVAGIERGFITREEGVQRFLKITSFLEKADKFHGAVSHFIDGT
                     TGKTVAFFGPKDNGGDLVETSFLFQGLLTARQYFNQENDKEKQIRKSIDNLWKNVEWS
                     WYKQFKDSPYLYWHWSPDQAWVINHKLIGWNETMITYMLAIMGPKYGISPEMYYSGWA
                     SQEEYAQEYRADWGRVEDGKMYTNGNTYYGENLKVGVSNGGPLFFIHYSYLGLDPHKF
                     TDKYTNYFENNQKMAKINQRYCIENQGGYVGYGEDCWGLTASDFAWNYQAQEPMPHRD
                     NGTMAPTGALASFPYTPGASMKALRNYYRNYGSFLWGEYGFRDAFNLTVNWVSPLFMG
                     LNQAPVTVMIENYRTNLLWNLFMSHPDVQKGIQKIQSIK"
     gene            complement(12089..13585)
                     /locus_tag="ACZPB4_11845"
     CDS             complement(12089..13585)
                     /locus_tag="ACZPB4_11845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009016767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RagB/SusD family nutrient uptake outer membrane
                     protein"
                     /protein_id="HIR1098938.1"
                     /translation="MKNILKKQILWAIPLAFSLLTSSCSDYLDKLPENTVEVEGIDYT
                     NKSNMYMPVSGVYATARGYLGSWSSYGCIIVRGDDVNKGGSPTDQIEYEYASKFQYDR
                     LTTFWALSGLWGNCYYVVSTSNSALESLENYAKHLTSESDKQLNAQYAAEVRFFRAYA
                     YFQLVNLFGDVPLLLDNQELNVFKNTKEDVKKYIYDELDYCIANLPAIRPNESEHPGA
                     VTKYTAEMLKAKQKMYDNEWDEVLALTEDIVNSGKFELYNDFYELFKIPGKLCNESLL
                     EYQFTDFGNGSGDIVSSDNWFAFQGPRGEAPISGWAFIEPTEKIRNLFSKRGEAVRAE
                     TTFLMTDATTRDGDYIPVAQPGEPTAYNGKAYTPANQMTPGRTGYGDNNNIRVFRYAD
                     VLLMNAEAKVRKGQNGDAPLNLVRERAGLAPIANATLDQILEERQVELALEWGERFFD
                     LVRTDRATQELPGFVKGESEYYPIPQDQIDLNPNLEAEPVPFEPEVTE"
     gene            complement(13610..16651)
                     /locus_tag="ACZPB4_11850"
     CDS             complement(13610..16651)
                     /locus_tag="ACZPB4_11850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SusC/RagA family TonB-linked outer membrane
                     protein"
                     /protein_id="HIR1098939.1"
                     /translation="MKAKLMLCLCLLLAATTMFAQNLTVTGVVTEKATGYPAIGVSVL
                     VKGTTNGTITSMDGDYTLSNVPKNATLVFSYVGMTTQEVPVNGQTVVNVLMSEDTQNL
                     EEVVVIGYGTSKAKDLTAPIAVIKADEITKHATSSPMSALQGKVPGVQITNSGQPGSG
                     PSVRIRGIGSMNTDSQPLYVVDGMFFDNIDFLNNSDIQDLSILKDASAASIYGVRAAN
                     GVVLVTTKKGALNRPATVTYDGYVGFQKATNVLKMANSEQYATMISEMGNETLQAVVN
                     NAKNVWGTLPNTNWYDEILHTALTHNHSLDISGGTEKATYSVGTSYLYQDGILDSKND
                     YSRFNLRTKADYKAFDWLKVGANVVLSNSTQNLPNGEVWLAAFRTPGIIPVYDENSSL
                     NPYPTKYGSPAQIGLSEYYYNPVAQAEYYDSKNSMLRVMPSFYAQFDFLPENKLFFKT
                     AYSQDINVIQTRAYTPEYLVGGTQLNSTPLLNKKNDIYHSWILDNTLTYTDTFGDHGL
                     TAMLGQSVREENWRNLWGEATGVPGGHEEYYYLNQGNADGRKTGDDGTTYRGVSWFGR
                     VSYDYKGKYLLSATMRADGSSKYQEKWGYFPSVGAAWNISEEGFMKDQKWVDYLKLRA
                     SWGKLGNDKVAASDGFASITQDMGTSGIFGGSAVPGYTNLVYFSWLGWEVVNETNVGL
                     DFRTLNSRLTIEADWYYRLTQNAVIDAPLPMGAGNLLGNRGEILNTGVELSFNWADKI
                     GKDFSYYIGANLTTLHNEVKDLNGLSYLYGGSAEFRTISQVGGELNAYYGYDIEGVYQ
                     NAAEIAADPIAVANGLEPGDFKYVDQNKDGKIDNKDRVTLGSYIPNFNYGINLGFSYK
                     NFDFSMVMQGVAGNQIVNRKRGDRRWHSELNYDLDQFENRWTGEGSTNEYMSAKGSVK
                     PWNISNFNSFYVEDGSYFRIQNVQVAYTFPKKDFGKFKMPSIRLSLTADRPLTVFKAN
                     SFSPELGSKNEKGEIASSSYGFDERVYPLASSYTLGLRIIY"
     gene            complement(16986..19844)
                     /locus_tag="ACZPB4_11855"
     CDS             complement(16986..19844)
                     /locus_tag="ACZPB4_11855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triple tyrosine motif-containing protein"
                     /protein_id="HIR1098940.1"
                     /translation="MLICCVIALLFCITGNAKVPYIPKIINYSVSDYKAGNQNWAVSQ
                     GPGGKMYIGNNRGLLVFDGIHWDLVKLPNNLGVRALYISKDGRIYVGSFEEFGYFEMD
                     DENDLIYHSLSSSEMNVYLNNDEFWTINEYKGEIYFQSFRSFFIYDGEKVRKGVSDLS
                     PLYIFTLDDHLYVQFMEGGSFCRMDDGQFTELLSKKVLEDDVVSVLPFDHQLLLVSAR
                     SGCFIYDEVRKKLSVWNTPANEILKEGIANRGVMMKDSTFIVGTISNGVVAINKQGET
                     LWHINRENGLINNTVLRVFADNSDNLWVTLDNGIAQIHVNSPIYFYEPLEAQIGMVHD
                     MVIEKGIVYLATNQGLYALSENDSYPTLIPGTQEQTWYISDVGNQLIAGHNTGTLQLE
                     GRKATQIPGPNGGGTALRKTIIHGKEVLLQMSYRPLSVFTRDMVTNRWKFSHNVEGFS
                     NLIKSFEVDPTGNIWASHMYKGIYRLRLNEDLRSVKEMEYIGKLEEGNESGTINVMKL
                     RGRIVFSDGSKFYTYEDLTGKIVPYDLLNEDFPELSDTYRVVSLNNDLYWFIRNSEYV
                     LLGYESGRFQLKQRIPFTLFDNPTIEDRGNIYVASDGTSYFCLNGGIARYDRYRNYVD
                     TTRVPLSLSLVRAYNRHENEFAPLPCKGADAPEAGASALSYSYNTILFKFSYPDFTGR
                     RFLIYYKLDGFDNEWIEGTSNFQRTYSNLPYGNFVLHAVVKDDRGKELSSLSYPFKIE
                     RPFYSSWWALIIYFALFLCILVVLVRMYTMWIVMREKKVNEEQKRLQEEQLRAQEQLI
                     VKLENEKLENDLTYKSKELASATLSVISHNDFLEGLKKEIQAQQLSGSYTKRFFDKLI
                     RMIEENISGEDEWAIFQTNFDRIHEKFFTNLKERYPDLTPGDLRLCALLRLNMPTKDM
                     ARMQNLSVRGIEAARYRLRKKLNLPEGQSLVDFMIQFH"
     gene            complement(19936..>20757)
                     /locus_tag="ACZPB4_11860"
     CDS             complement(19936..>20757)
                     /locus_tag="ACZPB4_11860"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 16 protein"
                     /protein_id="HIR1098941.1"
                     /translation="SFLLFGFILYSVFLSSLANASDIDLSAPMDKGGWKLIWSEEFDY
                     TGFPDSTKWSYDTEGNVYQWGNNEAQYYTSGRKENAWVSDGVLRITALKEPMEGRSYT
                     SARLITKGKGDWLYGRFEIRAKLPTGRGTWPAIWMLPTDWEYGDWPKSGEIDIMENVG
                     YDPDTIVGSSHTEKYNHAIGTQKNAKIACTDCYKAFHVYALEWEEDEYRLYVDDQLYF
                     TFKNEGTGYEVWPYDKRFHILLNLAIGGNWGGQKGIDDSLFPHVFEIDYVRVYKK"
BASE COUNT         5937 a         5467 c         3914 g         5439 t
ORIGIN      
        1 ttcttgccct caccgatacc gaacacacgc aagtccgaga tcgccagatg aggcgtcggg
       61 acctctatat tcttataacg gacataacgg acacgagccg gattatccac ttgtacgtaa
      121 tcgttcggga catccttata attattccgg cgatccacca acgttaccca atcctgcccg
      181 tccaaagagc cttccaccgc ataacggtgg cgtaaaccgg gaatacgtcc atacatattc
      241 gattgatgat cgtgataatt cacttgcacg gcatacaccg tagcgggagc ctccagatcg
      301 atctctaccc attcggtatc tccattcgtg cgagccatcc agaatgtctt acattcctca
      361 tccgtcaagt tggccggaag gaaattggcg gaagtcttgg gacggttcga ttccgtgaat
      421 ccttgcgcgg caggagcgga accctccgca tacgaggaag ctttcaccgg ctttttataa
      481 gaaagcaaca tccaccccgt aaactctcct ttctttcccg gctcggcggg agcgtaatgc
      541 ggataatcac cgaagttatt atcacaatac ataatgccct ccttatcgaa gaaagtagga
      601 tacatgcaga ggcgacgctc ccaattcacc gtagccgaga gagacataga ggcgaaatgc
      661 caataattac ctcccggccc caccaaggta cttccgtgtc cggcaccatt catgaaacca
      721 ccgggcttat agcttaccgg gttatgcgat tggtatttat acggacctaa tggggagtcc
      781 gccacataaa caccatcggc atatacgttg aattccgtac cgggggcggc atactgcata
      841 taatatttac cgtcgtgctt ggtcagccaa gccccttcca tatagccccc caataccgta
      901 tcggtatggt tctcgccaaa acgttcccag ccatgcttcg gcatatccaa gccgaaaagc
      961 tcgaccgtct cgccctcgat caagaaacgg tcatccttat tcagtttctt gccccgaagc
     1021 ggataaacat tggaagagcc ccagaataaa taagcttgcc cgtcatcatc gatgaataaa
     1081 tccgggtctt gtaggtcgtg gagtatagca ggagtagcgt tccaattacc caatttcgga
     1141 tcatcggtat aaagaacgct catggagccg gacggatcac ccatcacata aagcacggaa
     1201 tccttataat tatgagcggc gggagcgttg gaaccctgag gataccagtt tttaccggga
     1261 gtgataaaat cccagttcaa caaatctttc gaatgccaat agccatgcga acgggttacg
     1321 aacatataat actcgccccg gaattctacg acagcggggt ccgcacccga acggtaagac
     1381 aggttgttcg atgagttata aatcatatac gtataatcca cattaagcgg attacaatac
     1441 gtattcgccc gcatggattg agcggtggcg gaacctccgg aagcagccaa gaatagagcg
     1501 gaaaagatat attttgataa tagtttcatg ttgatatgta ttaattttta ccgcagagag
     1561 aaagaagact gattcgcctc gtcggcagaa ttcaagccta cccaaaccgt gaaatcaccc
     1621 ggctcggctt tcttctgcat atcgatacca tagaaagcca gcaaagcttc gtcaatcgtg
     1681 aaagagactt gcttcttctc gcccgctttc aaagtcacct tctcgaaacc tttcagctct
     1741 ttaaccggac gggtcacgct acccgccaag tcgcggatat acatctggac gaccgtctcg
     1801 ccatccacct tacccgtatt ctctacctca gccattaccg tgatcttgcc ccctttcgtg
     1861 aaagagttct gatccagctt catagagttc acggcgaaag tcgtatagct caagccataa
     1921 ccgaacggat acaacggtgt gttaggcaca tccatatatc tggatttata atccgtatcc
     1981 ggagcttccg gaggaaccgg acggcctgtc ggtttctgat tgtaataaag aggcaactga
     2041 cccaccgtac gggggaaaga catcgtcagg cgagcggacg gattataatc gccactgatc
     2101 acatcggcca tgccatgacc cgccatcgta cccagatacc aagcctccaa gataccgtcg
     2161 acatgctgat cctcccaaga aagatccaaa ggacgtccgt tcaccaagat caaaccaaga
     2221 ggtttacccg tctttttcaa ttctttcaac aaggcttgtt gagcacccgg caatttcaag
     2281 tccgtacggc aagcggcctc accactccag ttgaaatcct cgcccatagc cgccaatacg
     2341 atatccgcac ggcgagccgt agcgatcgcc tcagcgaatt tagatgaatc atcagtcaag
     2401 agatcacatc cctcggcata aatgaacttc acgttcgtac cggcatattt ctcggtcaga
     2461 ccctcgaaca aagagatact ctcctcacgc tcaccccggc cggcccactc gccattctgg
     2521 ttgatcttat cttttaccat cgggccgatc aaggctaccg taatattctt atccttcgag
     2581 atcgggaaga agttattatc attcttcaaa aggacgatcg agcgagcgga agtctcacga
     2641 gcctcttgca agaactccgg cttcatgatc gtattcttct cacgctcatt gtccaagtaa
     2701 cgatacggat catcgaacaa gcccaagagg aacttcatct ccaagatgct cgccacggca
     2761 cggtcgatat tctcttccga gactttaccc tctttcacgg attgtacaag atattggctg
     2821 tagatgccac ccgtcatatc catatcgata ccggcgttcg cagccagttc cccagcctcc
     2881 ttgtcatttc gcacgatact atgggctacc atctcattga taccggtata atcggtaacc
     2941 acgaaaccat tgaagcccca gtccttacgt aacagatcgg tcatcaacca tttattaccc
     3001 gtgctgggca ctccgttgat ctcattgaag gaggccataa acgtagcgac tcccgcttcc
     3061 ttagccgcca aataaggcgg catataataa ttcatcaacg tattttgcga caactcggac
     3121 gtattataat cacgtccggc ctcagcggcc ccataagcgg caaagtgctt gcaacaagcc
     3181 aagaccgtat ttacgtcggc caacgaacgc caatcgtttc ctccttggaa accctcaaca
     3241 cgggccttcg cgatcaagct tcccaaatac gggtcctcac cggcaccttc cattacacgt
     3301 ccccaacggg catcccggga gatatccacc atcggggcga acgtccaagc gataccggaa
     3361 gcgctcgcct catccgccgc gatcgccgcg cttttacgca tccgctccaa atcccaagag
     3421 caggattccg ccaacggcat cgggaaaatc gtacgatagc cgtgcacgac atcataacca
     3481 aacaatacgg gtatcttcaa acggctctcg gacagagcca tctcttgcat tttacgtacg
     3541 ccatctaccg tatatacatt aaacaagctt cctacaagac cttgtttcag caaagtctca
     3601 taatcccccg tcataaccgg gccggtcaca tcccagttac aggagtattg ggccatctgc
     3661 cccacctttt cctccaaggt cattaattgg agcacagaat ctacacggcg ttcaatattt
     3721 ttgtcgccgc tgaagctttt ccaaccactt acagcgggtt gctggcatcc acctaaggta
     3781 gcggcaacgg ccgcaccagc gataaaagtc gttaaccttt tcattattcg tatctgtatt
     3841 atttgttcca agtcacctgc gccgatttca cgtcccggga gttcgtacct acgtaaatat
     3901 tgaataagcc cggttcccag atgtattcca atgcgctgtt ataaaatttc aagtcttccg
     3961 gcgtaatcgt aaaagagact tttcggctct cacccggttt caaggagatc ttctggaagt
     4021 tcttcaactc tttcatcgga cgggagatgc tggcagccgg atcgccgata tataactgta
     4081 cgacttcctc gccctctagc ttgcctgtat tcgtcacctg tacgctggcg gtcaatacac
     4141 cgttctctcc ttgcacactc gtcttatcca attgaagatc accgtaagag aaagtcgtat
     4201 aactcaagcc atagccaaac ggatacaaag gatcgttcgt gatatccaga tatttagaag
     4261 tgaaatgatc atctggattc attgggcggc ctgttttctt agcattgtaa tacaaaggaa
     4321 tctggcctac gctacgaggg aatgtggtcg tcaatttacc ggaaggattc acgtcgccga
     4381 acaatacgtc caccaatccg caagccgcgg cggaacctcc atgccaagcc tcaacgatcg
     4441 cagagaattg gttatcctcc cactccaagg tcaacggacg gccgttcgcc aagactaaca
     4501 ccaccggttt accggtctcc aacaaagctc tcaacagctc tttctggctc tccggcaaac
     4561 taatatccgc acggctgcaa gcctctccgg accagttatt cggttcaccc attacggcga
     4621 tgatacgatc cgcatctttc acttgctcaa ccgcttcctt caccaaacgg gtattctcca
     4681 ccggatcaac cttcaagcca ctggctttcg ccaacatcgg ctcgttcgtc aaattacatc
     4741 ccttggcaaa aatcacacgg gccttattgc caaccacttc cttcacggcc tgcactacgg
     4801 aagctgactt cgccgtatcg ataccacacc atgtcccgaa caactcaacc ttcttatccg
     4861 ccaacgggcc taccacggcg atcgtccctg tctttcgcaa aggcaacaaa cccttgtcat
     4921 tcttcaacaa gacaatggat ttgccggcga tatggcgagc cgtattcata tgctcatccg
     4981 tgaacgtatt ctttttcgcg cgatccgcat ccaagtagcg ataagggtcc tcgaacaagc
     5041 ctaatttata tttcgcctcc aatacacggc ggcaagcctg atcgatatcc gcttgagaca
     5101 cacggccctc ttccaacgac ttcttcaagg tcgtgatata accatttgtc atcatatcca
     5161 tatccaagcc ggcatgcaaa gccaaggccg atacggtctg cgtatcaccc aaaccatgat
     5221 tggtcatctc gccgatcgaa ttataatcgg aaacgacaaa cccattgaat ccccattgat
     5281 cacgaagtaa atcggtcaat aaccagcggt tacccgtagc cggaatcgcc tccaccaaat
     5341 taaaggaaga cataaccgtg gcacaaccag cctctacagc cgctttataa ggcgggaaat
     5401 actcattaaa catcttgata cggctcatat ccaccgtatt ataatcacga ccggcctcgg
     5461 aagcgccata caaggcaaag tgctttaagc aagacaagat cgtgttctct ttcgtcaagt
     5521 catctccttg atagcctctc accatggcgg cggcgatctt tccaccccac caagggtcct
     5581 ctccactacc ctcggcgata cgtccccaac gagcgtcacg ggcaatatcc accatcgggg
     5641 aatacgtcca tgtcacaccg tttgagctgg cctcgatagc ggcgatacgg gcactttgct
     5701 cgatcaacgt cgtatcccag ctacaagaca aagccaatgg gatcgggaag atcgtatgat
     5761 atccatgaat tacatccagt ccgaacaaaa gcggaattcc taagcgagat tccttaaccg
     5821 ctatctcctg caatttacgg aacgtctcca gctccgagcc tcccgtagca cccagccagc
     5881 cccgacgaat cgtctcgtcc gcaccttccg agccactcaa gatgccggga acaccaccac
     5941 cggacaagtt cagctgtccg atcttctcat ccaaagtcat tttacccatc aactgatcga
     6001 taaacgtatc catcgctctc gtatcttgaa cgggcttttg tccgtatgcc gcaagtgcca
     6061 aacaagcggc gaatgataat ataatctttc tcatgttatt taaatattaa gattctctcg
     6121 cattatggat cgtgaaaccc aatttcttca aaccgtcctg gatttccgga cagctcataa
     6181 acaaacgcca cagaaggccc gtacggtaat tctcgatcat cggggtgatc gtacattggt
     6241 ctatcgccag ataacgacgc ggataccaat tctcgccttc actgaaagcg tcgtaaaaac
     6301 catacttacc ccagatgcta tctcccagat tgaaatagaa atgcttcaat gccttcgagg
     6361 attcctccgg tgtatacgga taactgctca aagccgctgt cggcgtaatc accccatgat
     6421 cgttggaagg catatgcgcg ttatagcctt tcacggaata gctggcggtc aatccccagc
     6481 aagcgtcgct atatcccttg aagcccttcg gattctccgc acaataacgg taatcgatca
     6541 agacgtgatt ccggttcaag tcccagtagt tagcgtatcg atccgacaag cctaccggac
     6601 ataggccgat ataagaataa tgcgcccaaa acaacgggcc gccgtactcc tcggcataat
     6661 tatgtttcaa gatcaaaggt aaatcgtaag cgaccgcatc gctcttgatc ccccctttac
     6721 gagcccatcc gttatgataa gcggaagccg ggatcggata cgtaggcgaa gacgccgcca
     6781 aaatataagt aatcagacat tcattgtaac cttccaaagg aaaattcatc tcccatgcgt
     6841 aattcgggct ccaatgccaa tacaatacat cctgcccgtt caaataccag gtccattcca
     6901 tctcacgcca tagctggtca atcttcgcgg ccaacgcttt ctcgctctca ttaccatcct
     6961 tgaaatattg gcgtacgcat aagagacctt gcattaagaa agcgctctct accaaatcgc
     7021 ctccgttatc cttctggccg aaaggcttta ccttacccgt aggtccatgc atccagtgag
     7081 gccagacccc atggaaacga tcggccttcg ccaagtaatc agcgatttga tgaaaacggg
     7141 ccacaccttc ctcacgggtg ataaagccac gctcaatacc taccaacagc ccggcgatgc
     7201 caaaaccact acctccggtg gtcacgatat cagcgtcgtt ctcaggatac acgccatccg
     7261 tatggatacg ctcacaggcc agtccggagg taggctccgc accttcccac atataattaa
     7321 agtgagcctt ttgtatatag gtcaagaatt catcatccga ctgaaaatcc aacttacgct
     7381 cattggccgt agactctgcg gatgtgtcac ttttcttggc ctcatgacaa gcggtcaacg
     7441 aaaagccaag caacagggta acaacgcctg tacggaaata ggtattcata gatatataca
     7501 tttaaaatag ttatcgtctc aatactttac tcatcggtga acggccgctc tctcccaatg
     7561 cctcgatcga gaaataatag tccgtatcct tatccaagcc cctgaaatcg tacatcgtat
     7621 ctcccagtac cgtgatactg ttgtacaatt tatccggcgc tataccataa tagatattgt
     7681 aagcgtacgc ctcttttacc ggctcccaag tgatcatcgc attccgctta tccgcttttg
     7741 agcgttccac ctttaagttc ttaacggcgg cgggagcttc tcccaaacca tttccaaaaa
     7801 tacgaaatcc agacatagcg aagttgcccg aaggcacatg ttcgttcact attttcaaat
     7861 aacgggtttt caaaggctca cgtaactcga tatagtcgtg cggaacgtcc ttgtcgttat
     7921 cgctcttatc gactaccaat tcccaatttt gtccatctat agaatgataa atacgatatt
     7981 gatgatacaa gtccatcgcc ttattatgct gtacggctct atgctcgtaa tagttcaact
     8041 ggatcgcacg tacctctttc aatccctcta aagagatctg gagccattca cccggttctc
     8101 ccgagcgggc ggaccagaaa gtacgcatgc tctcatccgt tacattctct ggtactaacg
     8161 tactatccat ggaagaggcc atcaccggtt ttccatacga tagcaacatc caaccggaaa
     8221 acgtattcgc gatatcatct accttccctt tcggcgtaag caaaggatag tccccgaaag
     8281 cggtgttcga atacatcacg ccatccttat cgaatgccgt agggtacaaa ccgatacgac
     8341 gttcaaactt atatttcaag gaaagcatgc aagtagccac atgccagtaa ttgccatacg
     8401 catcctcgaa agtaccacca tggccggcac cttgtacaaa acctcccggc ttatagctca
     8461 ttgggttatg tttctggtag gtaaacgggc ccatcggttt gtcggataca tagacaccat
     8521 ccgcatagac cttgaactcc gttcccggcg caccgtattg gaaataatat ttaccgttat
     8581 gcttggtcac gaaagctcct tccgtaaaag gcgccaaagt cgtactatcg tcattgttca
     8641 tcccgaaacg ttcccatccg tgttcttccg ggcgcagcat catgatctct tggatcttgc
     8701 tgatcgggtg gaaatcacgg cgatccagtt ccactccctt caaagcgaac tcattacttg
     8761 aaccatagta catatacaaa cgtccgtcat catccagcaa aaatgccggg tcccagctag
     8821 gaagagccgt tttctccaca taccgcttga actttccgct tttcgggttc gtactatacc
     8881 aaataggcaa tcccgcatag gtagaaccgg tatagaacaa ggtatctcca cttacgaaag
     8941 ccgccggagc gcacaagtcg tcatcttccg gataacgttg gaaaccggcg aatacaaact
     9001 cccaattact caagtccttg gaataataga atccggcttg attcgtggcg aaaaggaaat
     9061 attccccttt atacatgacc atcatcggat cagccgtaga gcggaaagag ccattcttca
     9121 ccaaatccgg cagattcgcc cggaagcagt agctcaaatt catcgggttg caataggtag
     9181 agggatgatc ggccgtagcg tcgaaccagc gggtagcttg ctgaggagct tttacccgta
     9241 catcacgagg atccgcttcc atccggatat ctattttcgt atcgttatcg ccaaacgtgc
     9301 gataagcgta cttcatcccc ggataataca cgaataactc atgatcgtag cggcttgctt
     9361 gtatcttata atagcctgtc gcatcggtgg tataatgaac cgggctagcc gtgaacatca
     9421 ccgtagcgcc ttccaagggc ttgccgtccg gtccggtaat cgtaccttcc agaaaatgct
     9481 ctggggatac ggtaatatag taatcgctta cctgcccctt gatcacgatc acggaatctc
     9541 cccgctcgtt tacttgagcg tttacggtag agaccgcaaa gaaagaggca aggagtgata
     9601 cgagcataca cttattgtag gcttttaagg aagcgctaga aactcctacg tctttccgga
     9661 aaaacatgta cgtgttttcc gaaaaagacg tacatgtttc cgagaaaaca cgtacatgtt
     9721 ttttccaaga agcgatagcc ctatttattc tattacatgc cagcatatta tgttcaagat
     9781 aagttattgt tgttttttgt cgcattatta ttttatggat tgaatctttt ggataccttt
     9841 ctggacatcc ggatggctca tgaaaaggtt ccacaacaga ttcgtacggt aattctcgat
     9901 cataaccgtt acaggcgctt gattcaatcc cataaataag ggagataccc aatttacagt
     9961 caagttgaaa gcatcccgga aaccgtactc accccataag aagctgccgt agttacgata
    10021 ataattccgc aaggctttca tggaagcgcc cggcgtgtaa gggaaagaag ccagagcgcc
    10081 cgtaggtgcc atcgttccgt tatcccggtg cggcatcggc tcctgagctt gatagttcca
    10141 agcgaaatcg ctggcggtca atccccaaca atcttctcca taaccaacat accccccttg
    10201 gttctcgata caataccgtt gattgatctt tgccattttc tggttgttct cgaaataatt
    10261 cgtgtactta tccgtgaact tatgtgggtc cagcccgaga taggagtaat ggataaagaa
    10321 aagaggacct ccattagaga cacctacttt caagttctcc ccataataag tattgccatt
    10381 cgtatacatc ttaccatctt ctacacgccc ccaatcggca cggtattctt gcgcatactc
    10441 ctcttggctg gcccagccgc tataatacat ctccggagag attccgtatt tcggccccat
    10501 gatagccaac atataggtaa tcatggtctc attccagccg atcaatttat gattgatcac
    10561 ccacgcctga tctggagacc agtgccaata tagatatggg ctgtccttaa attgcttata
    10621 ccagctccat tccacgtttt tccatagatt atcgatgctc ttacggattt gtttctcctt
    10681 gtcattctct tggttgaaat attgacgagc cgttaacagc ccttggaata agaaagaggt
    10741 ctccaccaaa tcacctccat tatctttcgg gccgaagaaa gcgaccgtct tcccggttgt
    10801 cccatcaata aagtgagaga ccgccccatg aaatttatcc gctttctcca agaaagaagt
    10861 gattttcaag aaacgctgta cgccctcttc ccgggtgata aatccccgtt cgatacccgc
    10921 cacgatcgcc atgataccga agccggaagc cccggtagcg atcatatcat tccgtccggg
    10981 aatattctca cgggcaagac cgctgtttgg ctccgctccc tcccaataat aacggaagtt
    11041 cgcttcctgt accatatcca gcaattgctc gtccgtcatt ggataggtag tggccgagac
    11101 tgtctgggaa tcattggatt cattcagcgc ataatccacg gccgtcacct tataataagc
    11161 ctttttacca acctctccca agaaatcggt ataacgattc atccaagggc ggcggatagc
    11221 gaccggttgg taagtaaccc cgtcgaaaga acggtaaatg cgatagtatt ttatatcctc
    11281 cttcgattga ggaatccatt tgatatcgat atgacgctca tacgccttgg cttcctgcaa
    11341 gaccggagcg tttaaggcac ttaccgacgg gagggaagcc ggcaaaagct ctatatcgtc
    11401 cagataaatc gtatattcgt ttccatcggc cgtaccggga cgaagggcta cggccgctaa
    11461 tttcttgatg ttcgtatcgt tcacggcgtt taatccgaaa tcctccaatg gaatggatac
    11521 ggaatgccat acgccgggac gtgtatcttt cagataattt ctcaggttta ggtattgggt
    11581 atacgtgctg tccgcataac gaatagcgat attgggaaga gcggcagcat tcatgctctc
    11641 tctcaaccgc acttgcatag agagcgtaga gggctcacga aagaagtcat tgccacggac
    11701 cgggcaatat tgtatctcgc tataccaatc tccaccggga gcggatacat aggtaagctc
    11761 caaggaattg ccgggcgtaa aagcgacaga gccggcaact ggaagatgat gtctcgcatt
    11821 tttaatccaa gaaggtgagg tatatttcgc ttgagaataa aagtaatccc ctttcatcaa
    11881 gctattctcg aagaaaacat agtcgtaagg tttctccacc gcttgcaagc tggcggacaa
    11941 taagagagta gttagtaatg cgatgtgttt catgatgctg atatttatat aaataaacga
    12001 tatgatttga gataaaatag gcggtgccaa acgggttgac accgccttgc caaactacaa
    12061 aggtctagta aataatgaga atcttatatt actctgttac ttccggctca aaaggcacag
    12121 gctcagcttc taagttagga ttcaagtcaa tttgatcctg tggtatcgga taatattcgc
    12181 tttctccttt cacaaaaccc ggaagttctt gagtggctct gtccgtacgg actaaatcga
    12241 agaaacgttc gccccattcc aatgccaact caacttgacg ctcttccaga atttgatcca
    12301 aagtcgcatt tgcaatcgga gctaaaccag cacgttcgcg aaccaagttt aatggagcgt
    12361 ctccattttg tcccttacga actttagcct cagcgttcat taacaacaca tcagcataac
    12421 ggaatacacg gatattatta ttatcgccat atccagtacg tcccggagtc atttgattag
    12481 ccggtgtata agcctttcca ttataagcag tcggttcacc cggttgagcg acaggaatat
    12541 aatcaccgtc acgagtagtg gcatccgtca tgaggaacgt tgtttccgca cgaaccgctt
    12601 caccacgttt agagaataaa ttacggattt tctcagtcgg ctcaataaat gcccatccag
    12661 agataggagc ctctccacga ggaccttgga acgcaaacca gttgtcagaa gaaacgatat
    12721 caccacttcc atttccaaag tcagtaaatt gatactctag caaagactca ttacacaatt
    12781 ttcccggaat cttaaacaac tcatagaaat cattatacaa ctcaaacttt ccgctattga
    12841 cgatatcctc ggtcaaggcc aatacctcat cccattcatt atcatacatc ttctgtttcg
    12901 ctttcaacat ctcagcggta tattttgtaa ccgctcccgg atgctcagac tcattcggac
    12961 gaatagccgg taagtttgct atacaataat ccaactcgtc ataaatgtac ttctttacat
    13021 cctctttcgt attcttgaat acattcagtt cttgattgtc taacaaaaga ggcacatcgc
    13081 caaataaatt taccaactgg aaataagcat atgctcggaa aaagcgaact tcagcagcat
    13141 attgagcgtt taattgcttg tctgactcac tcgtcaaatg tttagcataa ttctctaaag
    13201 actccaatgc tgaattagaa gtagagacaa cataatagca gtttccccaa aggccactta
    13261 atgcccagaa agtagtcaaa cgatcatact ggaatttact agcatactca tactcaatct
    13321 ggtccgtagg agatcctcct ttattcacat cgtcaccgcg aactatgata catccatacg
    13381 aggaccaaga ccccagataa ccacgagcgg tcgcatatac accggaaaca ggcatataca
    13441 tattcgattt attcgtataa tcaataccct ctacctctac agtattctct ggaagcttat
    13501 ccaagtaatc actacaactg gatgtcagca atgaaaaggc taaagggata gcccataaaa
    13561 tctgtttttt taatatattt ttcatatact tctgattagc atttaaagat taataaataa
    13621 tacgaagacc taacgtataa gaagatgcta aaggatatac acgctcatca aatccataag
    13681 aagaagatgc tatctcacct ttctcgttct tactacccaa ctctgggctg aagctgtttg
    13741 ccttgaaaac agtcaaagga cgatcagcag tcaagctcaa acgaatgctc ggcatcttga
    13801 attttccaaa gtctttcttc gggaatgtat aagcaacttg tacattctga atacggaaat
    13861 aagaaccatc ttctacatag aatgagttaa agttagagat attccaaggt tttacagaac
    13921 ctttcgcaga catatattcg ttagtagagc cctcacctgt ccaacgattc tcgaactgat
    13981 ctaagtcata gttcaattca gagtgccaac ggcggtcacc acgtttacgg tttacgatct
    14041 ggtttccagc tacaccttgc ataaccatag agaaatcgaa attcttgtaa gagaatccta
    14101 agttgatacc gtaattgaag ttcgggatat aagaacccaa tgttacacgg tctttattat
    14161 caatcttacc atccttattt tggtcaacat acttgaaatc tccgggctcc aaaccatttg
    14221 ctacagcaat cggatcagca gcgatctctg cggcattctg ataaacaccc tcaatatcat
    14281 atccatagta agcattcaac tcaccaccaa cttgagaaat cgtacggaac tccgcagaac
    14341 caccatataa ataagataaa ccattcaaat cttttacctc attgtgcaag gttgtcaagt
    14401 ttgctccaat gtagtaagag aaatctttac cgatcttatc agcccagtta aaagacaact
    14461 caacacctgt attcaaaatc tcacctctgt tacctaataa gttaccggca cccattggca
    14521 gaggagcgtc gatcacggca ttttgagtca aacgataata ccagtctgcc tctattgtca
    14581 aacggctatt caacgtacga aaatctaaac cgacgttcgt ctcattcacg acttcccaac
    14641 ctaaccaact aaaataaacc aagtttgtat aaccaggaac agcgcttcct ccaaatatac
    14701 cagaggtacc catatcttgc gtaatggaag cgaaaccatc actagccgca accttatcgt
    14761 tacctaactt accccagctc gcacgtaatt tcagataatc aacccatttc tgatctttca
    14821 tgaatccttc ttctgaaata ttccaagcag cacctacaga agggaaataa ccccatttct
    14881 cttggtattt ggaagaacca tcagcacgca ttgtagcaga caataaatat ttgcctttat
    14941 aatcataaga tacacgaccg aaccaagaaa caccacgata agtcgtaccg tcatcgccag
    15001 ttttacgtcc atccgcatta ccttgattca aatagtaata ttcctcgtgt ccgcccggaa
    15061 cacctgtagc ttctccccat aggttacgcc agttctcttc acgtacggat tgacccaaca
    15121 tcgcggttaa accatgatca ccgaacgtat ctgtataggt caatgtatta tctaaaatcc
    15181 aactgtgata aatatcattc ttcttattca aaaggggagt cgaattcaac tgagttccac
    15241 caaccaaata ttcaggagta taagctcttg tctgaataac attgatatct tggctataag
    15301 ccgttttaaa gaataactta ttctccggca agaagtcgaa ttgcgcatag aaagaaggca
    15361 ttacgcgcaa cattgaattt ttagaatcat aatactccgc ttgagcgacc ggattgtagt
    15421 aatactcact caaaccgatt tgggcaggag aaccatattt cgtaggatac ggattcaagg
    15481 agctattttc atcatataca ggaataatac ccggtgtacg gaaagctgct aaccaaacct
    15541 cgccgtttgg caagttttgc gtagagttgc tcaaaacaac gttagcccct actttcaacc
    15601 aatcaaaagc cttataatcc gctttcgtac gcaaattgaa acgagagtaa tcatttttag
    15661 aatccaagat accatcttga tacaaataag aggtacccac agaataagta gctttttcag
    15721 tacctccaga aatgtctaaa gaatggttgt gagttaaagc tgtatgtaag atctcatcat
    15781 accagtttgt attcggaagt gttccccaaa catttttagc gttatttaca acagcctgta
    15841 aggtttcatt acccatctca ctgatcatag tcgcatattg ctcactatta gccattttca
    15901 atacattcgt agccttttga aagccaacat aaccatcata agtaaccgta gcaggacgat
    15961 tcaacgcacc tttctttgtc gtaaccaaga ctacgccatt cgccgcacgt acaccataaa
    16021 tagaagcggc agaagcatct ttcaaaatag acaaatcttg aatatcacta ttattcaaga
    16081 aatcaatatt atcaaagaac attccatcta caacatacaa aggttggcta tccgtattca
    16141 tagaaccgat accacgaata cgtacggaag gaccggaacc tggctggcca ctattcgtaa
    16201 tctgcacacc cggcactttt ccttgcaaag cactcatcgg agatgatgtc gcatgtttcg
    16261 taatctcatc agccttgatc acggcaattg gagctgtcaa atccttagcc ttactcgtac
    16321 cataaccgat aacgacaacc tcttccaagt tttgcgtatc ctcactcata agaacattta
    16381 ctacagtctg tccgttaacc ggaacttctt gtgtagtcat acctacataa ctaaatacta
    16441 aagtcgcatt cttgggaaca ttactcaaag tatagtctcc atccatagag gttatggtac
    16501 cgttagtcgt acccttaacc aaaacactca ccccgatagc cgggtatcct gtggcctttt
    16561 cagttaccac accagtaact gtcagattct gcgcaaacat tgttgtcgcg gcaagtaaca
    16621 ggcataaaca aagcattaat ttagctttca ttcattctag ttttaaagtt gaacatttgt
    16681 ttttacactc attattaaat ttgaagcaaa tgaacaccca aacctaaaaa agggcaaatt
    16741 tttgtatact tcaacactac tgcaagcctt gcgcaagcag aaaattacta cttttatact
    16801 actgcaatac atattaatta tcttattttc agttataata catttgttaa ttcaaaagga
    16861 gaacattata tgttattaaa cacatctcac taaatatggg aacacaaaaa tgacaaggaa
    16921 aactcatagt tatgattttc ttatttcata gttatgatat ttttcattca taactatgaa
    16981 atttcttagt ggaactggat catgaaatct accaagcttt gcccctccgg tagatttagt
    17041 tttttacgca atcgatagcg cgccgcctcg ataccacgta cggaaagatt ttgcatacga
    17101 gccatatcct tagttggcat attcaaacgt aataaagcgc ataatcgtaa atcgcccgga
    17161 gtcaaatcgg gataccgctc ttttagattc gtaaagaact tttcgtggat acgatcgaaa
    17221 ttagtctgga aaatggccca ttcatcctcg cctgatatat tctcttcgat catgcggatg
    17281 agcttatcga agaatcgttt cgtataactt cctgataatt gttgagcttg tatttccttt
    17341 tttagacctt caaggaaatc attatgagag ataacagaca aagtagcact ggctaattcc
    17401 ttactcttat aagtaaggtc attttctaat ttttcattct ctagcttgac aattaattgc
    17461 tcttgcgccc tcaattgctc ttcttgcaat ctcttttgct cctcgttaac ttttttctca
    17521 cgcatgacaa tccacatcgt atacattctc actaatacga ccagtataca taaaaacaaa
    17581 gcaaaataga tgatcagcgc ccaccaagag ctataaaatg gacgttcgat cttgaatgga
    17641 taagacagag aagatagctc ttttcctcga tcgtctttca caaccgcatg taacacaaaa
    17701 ttaccatagg gtaaattaga ataagtccgt tgaaaattac tggtgccttc tatccattca
    17761 ttatcaaatc cgtccaattt ataatagatc aggaaacggc gccccgtaaa atccggatac
    17821 gaaaacttga aaaggattgt attataacta taactcaatg cggacgcacc agcttccggt
    17881 gcgtccgctc ccttgcaagg gagcggagcg aactcatttt cgtgccgatt ataagctctt
    17941 actagcgaca aactcaatgg aactcgagtc gtatccacat aattccggta tctgtcataa
    18001 cgagcgatcc ccccgtttag acaaaaataa gacgtcccgt cggaagccac ataaatattt
    18061 cccctatcct ctatggtcgg attatcaaac aaagtaaaag gaatacgctg ttttaactgg
    18121 aatcgcccgg actcatatcc taacaataca tattccgaat tccggataaa ccaatataaa
    18181 tcattattca aggaaacaac tcgataggta tcgcttaact cgggaaaatc ctcattcaac
    18241 aaatcataag gaacgatctt tccagtcaaa tcctcataag tataaaactt actcccatcc
    18301 gagaaaacaa tacgtccgcg taatttcatt acattaatcg taccactctc attaccttcc
    18361 tccagttttc cgatatactc catctctttc acactcctca aatcctcatt caagcgaaga
    18421 cgatagatac ctttatacat atggctagcc catatattgc cggtagggtc aacctcaaac
    18481 gatttgatca aattagagaa tccttctaca ttatggctaa atttccaacg attagtaacc
    18541 atatcccggg tgaaaacact gagtggacgg taagacatct ggagtaaaac ttcctttcca
    18601 tggataattg tcttacgtaa tgcggtaccc cctccattgg gccccggtat ctgagtagct
    18661 tttcggccct ctagctgtaa ggtacctgta ttatgtccgg caatcagttg atttccgaca
    18721 tcggagatat accatgtctg ttcttgagta ccgggaatca aggttggata actatcattc
    18781 tcagataacg cataaagacc ttggttcgta gctaaataaa caataccctt ctctatcacc
    18841 atatcatgca ccataccaat ctgggcctca agcggttcat aaaaatagat cggagaattc
    18901 acatgtatct gcgcgatacc attatccaat gtaacccata aattatccga attatcagca
    18961 aatactctca ataccgtatt attaatcaag ccattctccc ggttgatatg ccacaaagtt
    19021 tccccctgct tattaatcgc tacaacccca ttagaaatcg tacccacaat aaaagtagaa
    19081 tctttcatca tgactccccg gtttgcgatc ccttccttta atatctcatt ggctggtgta
    19141 ttccacacag acaatttttt acgcacctca tcatagataa aacatccact acgagccgag
    19201 accaataata gctgatgatc aaatggcaag accgaaacca catcatcctc caaaaccttt
    19261 ttcgatagta actctgtaaa ctggccgtca tccattcgac aaaagcttcc tccctccatg
    19321 aactgaacgt atagatgatc gtctaatgtg aaaatataca atggagacag gtcggataca
    19381 ccttttctta ctttttcccc gtcataaata aaaaagctcc ggaatgattg aaaataaatc
    19441 tcacccttat attcattaat cgtccagaac tcatcattat tcagatagac attcatctca
    19501 gacgaactga gtgaatgata aatcagatca ttctcatcat ccatctcaaa atacccgaac
    19561 tcctcgaaag agccgacata aatacgtccg tccttcgata tatacaaagc acggacacct
    19621 agattattcg gtaatttcac aagatcccaa tgaataccgt caaaaaccaa aagcccccgg
    19681 ttattcccaa tatacatctt tcctcccgga ccttgggaga cggcccaatt ctggtttccc
    19741 gctttgtaat cgcttacgga ataattgatg attttaggaa tatagggtac cttcgcattc
    19801 cccgttatac aaaataacaa ggcaataacg caacaaatca acatacgaac caacgtcctc
    19861 ttaagtatct ccttcactat atagtacaga atgttatgta ccacaaaagt aaataaaaaa
    19921 acatcacgtt acaccctact tcttataaac tctcacataa tcaatctcga acacatgtgg
    19981 aaaaagagaa tcatcaatac ccttttggcc tccccaattc ccaccgatcg ccagattcag
    20041 caagatatga aagcgtttat cgtaaggcca aacctcatag cctgtcccct cgttcttaaa
    20101 tgtaaagtat aattgatcat ctacataaag ccggtactca tcttcctccc attccaaggc
    20161 gtacacgtga aacgctttat aacaatccgt acacgcaatt ttagcatttt tttgagttcc
    20221 gatcgcatga ttatattttt ccgtatgcga agaacctacg atcgtatcgg gatcatagcc
    20281 cacattttcc ataatatcta tttccccgct ttttggccaa tccccgtatt cccaatccgt
    20341 tggaagcatc cagatggccg gccatgtccc tcgtccggtc gggagtttcg cccgaatctc
    20401 aaaacgtccg tacaaccaat ccccttttcc tttcgtaatc agacgagccg atgtatatga
    20461 acgaccttcc atcggttctt tcaaggccgt aatcctcaat accccatccg agacccaagc
    20521 gttctccttt ctgccggatg tataatattg agcctcgtta tttccccatt gatatacatt
    20581 accttccgta tcataagacc atttcgtaga atcaggaaat cccgtatagt caaactcctc
    20641 actccatatc aatttccacc cgcctttatc catgggtgca gacaaatcga tatcactagc
    20701 attcgccaga ctgctcaaga aaacactata taggataaaa ccaaacaaaa gaaatga
//
LOCUS       DBMDTB010000074        20733 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_858_length_20733_cov_12.899040, whole genome shotgun sequence.
ACCESSION   DBMDTB010000074 DBMDTB010000000
VERSION     DBMDTB010000074.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 20733)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 20733)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20733
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_858_length_20733_cov_12.899040"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..432
                     /locus_tag="ACZPB4_11865"
     CDS             <1..432
                     /locus_tag="ACZPB4_11865"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HIR1098942.1"
                     /translation="SMESSFPDVIKFIESNYRVEKKKSSRAIAGLSMGGFHSLHISKQ
                     YPDMFDYVGLFSAAILPREGSESPIYQNMDEKLKVQFGKHPKLYWIAIGKTDFLYKNN
                     VDYRKKLDDNGYKYEYYESDGGHIWKNWRIYLTKFAPMLFK"
     gene            complement(498..1193)
                     /locus_tag="ACZPB4_11870"
     CDS             complement(498..1193)
                     /locus_tag="ACZPB4_11870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HIR1098943.1"
                     /translation="MTITCVITDDEPMARKGLQSYVERVDFLSLTGVCEDAIQLNTLL
                     KTQQPDLLLLDIEMPYLSGLDLLATLNQPPKVIVTSAYEQYALKGYELDVVDYLLKPI
                     SFERFLKGVNKVHDLLARENTPDADASFFVKSEKQMRKIYLRDILFVEALENYVSIYT
                     TSGRVLTHSTLKRIGESLPDDQFLQTHKSYIINADRVDLVEGNRLRIESYQIPIARNL
                     RDVVFKRILKNTL"
     gene            complement(1190..2248)
                     /locus_tag="ACZPB4_11875"
     CDS             complement(1190..2248)
                     /locus_tag="ACZPB4_11875"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1098944.1"
                     /translation="MKKIYKWIYALIFAVSLYSCIRWVTDYTKEGHYWTQSLRNSILE
                     IVILAFVSYLFFIYFRRLIEKSRRAKEPNRWKFVWRSYGMPFLLIILGVNATLAITRI
                     FTGDTFHMDAIIIANVIGSLFAFMVYNVQRAQVLDKDYAEQRIQLEKIKNDQLQTELK
                     FLKSQYHPHFLFNALNTVYFQIDESNKAPRRTLEMISELLRYQLYGGNQKVSILQEID
                     YLKTYIALRKLRMSERLRLRVEFPPELNELNIYPLLFLPLVENAFKYVGGDYQLDIIM
                     KWENNRISLFIRNSIPELSAEDEALRKSVDERQRKGIGLVNLRRRLSLLYPNKHRLET
                     RKEETEFVAELMIEIEDI"
     gene            complement(2269..4428)
                     /locus_tag="ACZPB4_11880"
     CDS             complement(2269..4428)
                     /locus_tag="ACZPB4_11880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane beta-barrel protein"
                     /protein_id="HIR1098945.1"
                     /translation="MSRNLFIIVLLIITPFCGWGQVDTIADQKLQEVVIMAKLPTVEM
                     KPGKMTYRLDASITQSQGNVYDVLTSLPGVVIQNDGTIFLNGQNGANILMDGKPTYLS
                     GQDLVNLLKSTPASITDKIDLITQPSARYDASGNSGIIDIRTKKILRRGMNLSVNGSY
                     DQGKYGEGFASTTLNLRTNKFNFYLSYSYSRKNDYDDLYVERNYLEGWRPEGETGQMT
                     QSSYRTWKNTSNYYRFGIDYQMSDKTTIGFSTDGNLAGNKVEGDMNSSIPKRSPQTGG
                     SLRTLNDQNRSQDNFTAVLSLTHTFNSDGGVLDASMDYLRYRYEEDQYLNSQDTLFGD
                     MDGGIHLYSGQANLVWPFSKSFTFHAGAKTSFVSIDNNADYNRLQGDSWQPDHDLSCD
                     FQYDENINAGYVQLDAKFSSISLEAGLRLENTRIEGEQSGNAYQRDSSFTNHYTHLFP
                     TLSVQYALRNGNSLSLTYGKRIVRPNYRDLNPFVYIHDEYTYDKGNTLLRPELSDNLE
                     LAYIHGDLFRVGLAFNYTKDVIIKSYLDQGNYVVYVSPENLSSRVSVGPRLSTSQLPL
                     TSFWNVNVSASLIYNRYRLPENYQVKVNKRWTPNIGISNQFSFARTWSAELIGFYNGK
                     MAAGQATIYPLWQINAGIQKKIWKGRGTIQLFARDIFHSNVSRMSVMTPTQHAFIKER
                     MNRTVVGISLTYRINRGLEVKESRRKHSVDESKRINL"
     gene            5031..5201
                     /locus_tag="ACZPB4_11885"
                     /pseudo
     CDS             5031..5201
                     /locus_tag="ACZPB4_11885"
                     /inference="COORDINATES: protein motif:HMM:NF018425.6"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            5261..5458
                     /locus_tag="ACZPB4_11890"
     CDS             5261..5458
                     /locus_tag="ACZPB4_11890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098946.1"
                     /translation="MEVTVKKVEITLPEVDMALLKELAKKFGWNIGRKKSGIEKGLED
                     IKAGRTHKAKNAEDMFQQILG"
     gene            5462..5734
                     /locus_tag="ACZPB4_11895"
     CDS             5462..5734
                     /locus_tag="ACZPB4_11895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0090729 - toxin activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HIR1098947.1"
                     /translation="MYRLEYTTNFKKDLKTCKKRGLELHLLQRVIDILQETGTLPNQY
                     RPHKLSGKFEGLWECHIKSDWLLIWQQNDTELVLIMTDTGTHADLY"
     gene            complement(5739..6329)
                     /gene="folE"
                     /locus_tag="ACZPB4_11900"
     CDS             complement(5739..6329)
                     /gene="folE"
                     /locus_tag="ACZPB4_11900"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010185314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003934 - GTP cyclohydrolase I activity
                     [Evidence IEA];
                     GO_process: GO:0046654 - tetrahydrofolate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HIR1098948.1"
                     /translation="MSEVNEETLCAREALAGHYKEVLGLLGEDVEREGLLKTPERVAK
                     AMQFLTKGYHEDPEAVLRSAMFQEEDYKQMVIVKDIDFFSLCEHHMLPFFGKAHVAYI
                     PKKYITGLSKIPRVVDIFARRLQIQERMTMQIKDCIQRTLDPLGVMVVIEAQHMCMQM
                     RGVEKQNSLTTTSDFTGFFQQAKTREEFMNLIKHNR"
     gene            complement(6335..6841)
                     /locus_tag="ACZPB4_11905"
     CDS             complement(6335..6841)
                     /locus_tag="ACZPB4_11905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPOR domain-containing protein"
                     /protein_id="HIR1098949.1"
                     /translation="MKRIPCILLLFAFLMAGTSSLFAQTALEGERSTIFDALRRSGLG
                     KGEVVINQSAAIGEMVGERMRGANVETTDSLTFLKVQGYRTQVFSGNNQRVSKDEAFR
                     KEKEIKELFPEVPTYVTYNAPFWKLRVGDFRSHEEAYHMMRLLMGAFPKYGKEMYIVR
                     EEIKIPLN"
     gene            complement(6910..7665)
                     /gene="tpiA"
                     /locus_tag="ACZPB4_11910"
     CDS             complement(6910..7665)
                     /gene="tpiA"
                     /locus_tag="ACZPB4_11910"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012457684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HIR1098950.1"
                     /translation="MRKNIVAGNWKMNTTLAEGLALAKGLDEALKGKTPNCDVIIGTP
                     FTHLASVAAAIDTNKIGVAAENCADKEKGAYTGEVSAAMVASTGAKYVILGHSERRAY
                     YHETPEILKTKVELALANGLTPIFCIGEVLEEREAGKHFEVVDAQIAGSLFDLSAEDF
                     GKIILAYEPVWAIGTGKTASAEQAEEIHAHIRATLAAKYGNEVADNCTILYGGSCNAG
                     NAKELFAKPNVDGGLIGGASLSVDKFMPIIEAF"
     gene            complement(7702..8985)
                     /locus_tag="ACZPB4_11915"
     CDS             complement(7702..8985)
                     /locus_tag="ACZPB4_11915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BT_3928 family protein"
                     /protein_id="HIR1098951.1"
                     /translation="MEYKETVKKVIAEVCRLLLGVVFIFSGTVKAVDPMGGAIKIGDY
                     LTSFGLDKLQPFTVLISFNLSALEFMLGVCMLLGVYRRYTTFLTLLMMSFMTPLTLYL
                     AIFNPVSDCGCFGDALVISNWQTFYKNVVLLAAAIYVFIHNQRLLQGYTYHAYWFVAL
                     WSYVFAIGFAYRNYNHLPILDFRPYKLGANIPALMSIPEGAPEDEYAYSFIYERDGVQ
                     KEFSLENAPADDSTWTFVDSKTKLIKQGYVPPVTTFHIYNENDADVTDELLNDPKGLF
                     LLIAPRLENADDERIDEINNVYDYALENGLGFYCVTGSSAEAIATWSDNTGAEYPFLM
                     ADDVLLKTIIRSNPGLVLLKKGTILMKWHYNDIPQEEDLKTIVNGYLEGNTDWKAKED
                     ARLITNLLSFTVPLLLVWGYDALRNRRRRKGKESE"
     gene            complement(8991..9536)
                     /locus_tag="ACZPB4_11920"
     CDS             complement(8991..9536)
                     /locus_tag="ACZPB4_11920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1599 domain-containing protein"
                     /protein_id="HIR1098952.1"
                     /translation="MPNTKEQFEQVISLCRELFEKKLKDYGPSWRIMRPQSVTDQIFI
                     KANRIRSLEIKGTSMVDEGIRPEFIAIVNYGVIGLIQLALGFADTTDITIEKALELYD
                     KYIAETKELMYAKNHDYDEAWRSMRISSYTDLILMKIYRTKQIESHGGKTLVSEGVDA
                     NYMDMINYALFGLIKLEFGEE"
     gene            complement(9695..10945)
                     /locus_tag="ACZPB4_11925"
     CDS             complement(9695..10945)
                     /locus_tag="ACZPB4_11925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HIR1098953.1"
                     /translation="MSIRTFLFICCAAVMVSTANAENPVKPETPETPNHPTHKLMDKR
                     VSELMADRVGFKKDMALKELAEINEKAELEARENLMFPADELYGEWTNEWVNPFRGKK
                     VDMPDSCVIDCSTFVLPMDSMTRVTSKYGPRRRRMHKGIDLKVQIGDTIRAAFDGKVR
                     IKNFERRGYGYYLVIRHPNGLETVYGHLSKFLVGVNDIVRAGDPIALGGNTGRSTGSH
                     LHFETRFLGQAINPADIIDFENSIPHQDQYVFRNVKINGRKSNIYTSSNSQMVYHRVK
                     SGDTLGKIARIYGTTVNELCRLNGLKSTSMLRIGQSIRCSAGVETAAKATPKAQTQKK
                     STASASSKKITVQASSSATASLGEDTNTMNDVEATSVYHRIKSGDTLGAIAKRYGTSV
                     SKLCELNGITKTTVLRLGRSLRCS"
     gene            complement(11156..13252)
                     /gene="recG"
                     /locus_tag="ACZPB4_11930"
     CDS             complement(11156..13252)
                     /gene="recG"
                     /locus_tag="ACZPB4_11930"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008153941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HIR1098954.1"
                     /translation="MLDLDKRSITYLPGVGPKKADILQKEAGISSYEDLLFYFPYKYI
                     DRSRFYKVAEISGNMPYIQLKGQILYFDTLGEGRSKRLVGKFSDGTGTIDLVWFKGLN
                     YVTDKYRPNTEYIVFGKPTEFGHTYNIPHPDIDSMEQADQVANGLTPFYNTSEKMKKS
                     FLNSRAIQNLQYTLLSWLNWELPETLSPDVLKRIHMMSMTEAMRNIHFPESAAKLRDA
                     QLRLKFDELFFIQLNILRTASVRKLKLKGIIFPTVGHYFNTFYKEYLPFELTNAQKRV
                     VREIRIDMGSGRQMNRLLQGDVGSGKTLVGLLSMLLAIDNHCQACMMAPTEILATQHY
                     ATIMGFLKDMDVKVALLTGSTKKKERDKILPAIASGEIQIVIGTHALIEETVVFSSLG
                     LAIIDEQHRFGVEQRSRLWMKNAIVPHVLVMTATPIPRTLAMTLYGDLDVSVIDELPP
                     GRKPIQTLHRYDNKKAQLYEFLRKEIQKGRQVYVVYPLIEGNEKLDYKDLEAGFETFK
                     EVFPEYKVCMVHGRMKAADKDTEMQKFISGEAQILMATTVIEVGVNVPNASVMVIESA
                     ERFGLSQLHQLRGRVGRGAEQSYCILVSSYKLSNDTRKRLEIMVNSTNGFEIAEADLR
                     LRGHGDLEGTRQSGEGIDLKIADLAADGQILQYARDIAQGVLDEDPELLSEQHRILSE
                     RLKTLFTRKINWGMIS"
     gene            complement(13275..13973)
                     /locus_tag="ACZPB4_11935"
     CDS             complement(13275..13973)
                     /locus_tag="ACZPB4_11935"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HIR1098955.1"
                     /translation="MNKYVLIVAGGKGLRMGGDLPKQFIPMRGKPLLMHTLEAFHRWD
                     ASARIILVLPEDHQPYWNMLCKEIGCKVPHAIVKGGDTRFFSVKNGLDWLLAERRRKG
                     EEDSGLSLVAVHDGVRPFVSPEVVEACFDKAAVTGAVIPVVPMIDSLRETDEKGSHPV
                     DRSRYMAVQTPQVFLLELLTKAYEQPYSSLFTDDASVVEAMGHAIDTVPGDRENIKIT
                     TPFDLLIAEAMFAR"
     gene            complement(13973..14170)
                     /gene="xseB"
                     /locus_tag="ACZPB4_11940"
     CDS             complement(13973..14170)
                     /gene="xseB"
                     /locus_tag="ACZPB4_11940"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HIR1098956.1"
                     /translation="MAKKEETYNEAIEKLRKIVAEIENGDLDVDILSEKVKEATRLIK
                     LCKEKLYKVDEEVKKVLEELD"
     gene            complement(14210..15544)
                     /gene="xseA"
                     /locus_tag="ACZPB4_11945"
     CDS             complement(14210..15544)
                     /gene="xseA"
                     /locus_tag="ACZPB4_11945"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HIR1098957.1"
                     /translation="MRPNLNNLSGEKEALSLLELNTRIRGALSRAFPETCWVRAEMSD
                     VRVNTSSGHCYLEFVEKNVQTGQLVAKVRGSIWAKTFRMLKPYFEMETGQMFASGLKV
                     LVKVSVEFHELYGLSLTVLDIDPAYTLGDMVRKRMEIIRQLQEEGVFTLNKELPFPLL
                     PRRIAIITSPTAAGYEDFMNQLTRNKGGYPFYTKLFPALMQGERTEASVIAALDRIYQ
                     HQDLFDVVVIIRGGGATSDLNSFDSYLLAANCAQFPLPIITGIGHERDDTVVDLVAHT
                     RMKTPTAVAEFLISRMDSVGEELESLRQDVSLLAMDILSRQKNYLQLVATRFPSIVTS
                     RIERNRSGLQTIASRLPAMASGLLSRRQSVLENTELRLRNGITSKLSESGRFIQLTEQ
                     FIKMASPDYILKRGYSLALKDGKIIKHASDLRAGEELTTRFIDGEIKSIIKP"
     gene            complement(15525..16907)
                     /locus_tag="ACZPB4_11950"
     CDS             complement(15525..16907)
                     /locus_tag="ACZPB4_11950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HIR1098958.1"
                     /translation="MSKYIGIFVFVFSLFSLGVHAGESFRFRVYLKDKGDSGYTLDNP
                     EEYLSKESVERRNRQGISVSESDLPIAQAYLDTLSANGGKPVLESKWFSTVVVSSPDS
                     LVAERLLRLPIVDSVKWVWKGDEEIDIPREENDTTRFMPIDKPEKSPYGYAEEQIKML
                     NGIKLHEAGFKGKGMRVAVVDAGFMNVDRISVFDSLRLLGTHNVVFPGRSVFIGDDHG
                     TKVLSCLAADAPGLMVGTAPQAEYWLIKSEDSRSEFPIEEDYWTAAMEFADSVGVDVV
                     SSSLGYFSFDVEALNYHQDQLDGRTSLISRAAKMASSKGILLFSSAGNEGGGSWGKIT
                     FPADAPDILTVGAITDRKKKSNFSSVGFTADYRVKPDVVALGTGCCVIDPTGNIRYAN
                     GTSFATPILAGLGVCLWQAFPSLTNKDIISLLQRFGSKFEQPDAELGYGIPDVYKAYK
                     QERKYAAESK"
     gene            complement(17009..17476)
                     /locus_tag="ACZPB4_11955"
     CDS             complement(17009..17476)
                     /locus_tag="ACZPB4_11955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HIR1098959.1"
                     /translation="MEKIDKLDRQILNIISKNARIPFKDVAEECGVSRAAIHQRVQRM
                     IDMNVIVGSGYHINPKILGYNTCTYIGVKLERGSMYKDVVPEFEKIPEVVECHFTTGP
                     YTMLIKLYARDNEHLMELLNSKIQEIPGVTATETLISLRQSVKREIPICNINE"
     gene            complement(17661..18371)
                     /locus_tag="ACZPB4_11960"
     CDS             complement(17661..18371)
                     /locus_tag="ACZPB4_11960"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HIR1098960.1"
                     /translation="MKKLSVLVATVIVAMGASFTSCGDSHKSASLKTSIDSASYAIGI
                     STGAGYKENLKTLPGGEANVDDLIAGFIQAIKGDSSAMKMNPQQAQQYLQTYFVEAQA
                     REAKKTKEEGDKFLAENKTKEGVITTESGLQYKVEKEGTGAKPTATDKVKVHYTGTLL
                     DGTKFDSSVDRGEPAEFGVGQVIKGWTEGLQIMPVGSKYIFWIPAELAYGERGAGQDI
                     KPNSVLKFEVELLDIVKE"
     gene            complement(18392..18979)
                     /locus_tag="ACZPB4_11965"
     CDS             complement(18392..18979)
                     /locus_tag="ACZPB4_11965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HIR1098961.1"
                     /translation="MDKVSYALGLSIGNNFQNSGIKDLQVEDFVQGLNDVLTEAKPAL
                     SYDEAKQVINDYFMKLQQEKLEINKKAGEEFLSINKHKAGVVELPSGLQYEVLKNGTG
                     AKPTANDKVKCHYHGTLINGQVFDSSVQRGEPAVFGVSQVIPGWVEALQLMPVGSKWR
                     LFIPSNLAYGERGAGEAIEPNSTLIFDVELLDIEK"
     gene            19141..19830
                     /locus_tag="ACZPB4_11970"
     CDS             19141..19830
                     /locus_tag="ACZPB4_11970"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0017136 - histone deacetylase activity,
                     NAD-dependent [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family NAD-dependent protein deacylase"
                     /protein_id="HIR1098962.1"
                     /translation="MKKLVILTGAGMSAESGISTFRDSDGLWEKYRVEDVATPEGFAA
                     NPKLVLDFYNQRRRELLNTKPNAGHLGLAALEKDFDVRIITQNIDNLHERAGSSHVIH
                     LHGELMKACSVRDLDTTYNLSPENPDIHLGDKDPHGNQLRPFVVWFGEAVPMIEPSIK
                     LVEDCDIFVIIGTSLNVYPAAGLLNYVRRGQPIYLIDPKDVRTYRDDIEHIQAGASEG
                     VKRLTELLTQN"
     gene            complement(20074..20301)
                     /locus_tag="ACZPB4_11975"
                     /pseudo
     CDS             complement(20074..20301)
                     /locus_tag="ACZPB4_11975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860948.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6383 domain-containing protein"
BASE COUNT         5875 a         5320 c         4045 g         5493 t
ORIGIN      
        1 agcatggaaa gcagcttccc ggatgtcatt aagtttatcg agagcaatta ccgtgtggaa
       61 aaaaagaaat ccagccgtgc gatagccgga ctttccatgg gtggtttcca ttctttgcat
      121 atatctaagc aatatccgga tatgttcgat tacgtgggat tattctctgc cgctatcctc
      181 ccccgcgaag gctccgaatc tcccatctac cagaatatgg atgagaagct gaaagtacaa
      241 tttggcaagc acccgaaatt atactggatc gctatcggta aaaccgactt cttatacaaa
      301 aacaacgtag actatcgtaa gaaactagac gataacggct acaaatacga atactacgag
      361 agcgacggcg gccatatctg gaagaactgg cgcatctacc tcacaaaatt cgccccaatg
      421 ttattcaaat aacaaaatac ccagttgtag agacgcggca tgtgccgcgt ctctatgacc
      481 tagctacagt catataatta caacgtattc ttaaggatac gcttaaatac aacatctctg
      541 agattacggg cgatcgggat ttgataggat tcgatacgta atctattccc ttctaccaga
      601 tcgacacgat ccgcattaat tatatacgat ttatgcgttt ggagaaattg atcatcgggt
      661 agggattccc cgatccgctt caaggttgaa tgggtcaata ctctaccgga agtagtatag
      721 atactaacat aattttccaa cgcctctaca aataagatat ctcttaggta gatcttacgc
      781 atttgcttct cgcttttcac gaagaacgag gcatccgcat ccggcgtatt ctcccgagcc
      841 aacaggtcgt gcaccttatt cacgcctttt aagaaacgct caaaggaaat aggcttcagc
      901 aaataatcca cgacatccag ctcatatcct ttcaaggcat attgctcata agcggaagta
      961 acgatcactt tgggaggctg gtttaaggtc gccaataaat ccaaaccgga aagataaggc
     1021 atctcgatat ctaacaaaag taaatccggc tgctgagttt tcaacagggt atttaattgg
     1081 atagcgtcct cacatacacc ggtcaaggag agaaaatcca ctcgctccac atacgattgc
     1141 aatcctttac gggccatcgg ctcatcatct gttatcacgc aggttattgt catatatctt
     1201 ctatttcaat cattaattcc gctacgaact cagtctcttc tttccgggtt tccaaacggt
     1261 gcttattggg atacaataaa gataatcggc ggcgtaaatt taccagaccg atgcctttac
     1321 gttgccgttc atccaccgat ttacgcaacg cttcgtcctc cgctgaaagc tcggggatgg
     1381 agtttcgtat aaacaaactg atccggttat tttcccattt catgataata tccaattgat
     1441 aatcgccacc tacgtattta aaagcgttct ctaccaacgg gaggaagagt aacggataaa
     1501 tattcagttc attcaattcg ggcggaaact ctacacgcaa ccgcaggcgt tcactcatac
     1561 gaagcttacg caaagctata taagttttca aataatcaat ttcttgtagg atactgacct
     1621 tctgattacc gccatacagt tggtaacgca agagttcgga tatcatctct aacgtgcgac
     1681 gaggcgcctt gttactttca tcaatctgga aataaacggt attgagcgca ttaaacaaga
     1741 agtgaggatg atattgggat ttcaagaact tcaattccgt ctgtaattga tcattcttga
     1801 tcttttccag ttggatacgc tgctcggcgt aatctttatc caatacttga gctcgctgaa
     1861 cattatagac cataaacgca aacaagctcc ctatcacgtt cgcaattatt atagcgtcca
     1921 tatggaaagt atcaccggta aatatacggg taattgccaa cgtagcattc actcccaata
     1981 taatcaataa gaaaggcatt ccatacgatc tccaaacaaa tttccaccta ttcggttctt
     2041 tcgctcttcg gctcttctcg atcagccgtc tgaaataaat aaaaaacaaa taagagacaa
     2101 atgcaaggat cacgatctct aggatactat tcctcaagga ctgtgtccag tagtgtcctt
     2161 ctttcgtata atccgttacc cagcggatac aagaatacaa agagaccgca aaaatcaagg
     2221 catatatcca cttatatatc tttttcataa accatttgtc tagaggtttc acaaatttat
     2281 tcttttactt tcatctacgc tatgcttccg gcgagattct ttcacctcca aaccacgatt
     2341 tatacgatag gtcaatgaaa taccgactac tgtccggttc atccgctctt ttataaaagc
     2401 gtgctgggtg ggagtcatca cgctcattct cgatacattc gaatggaaaa tatcccgtgc
     2461 gaataactgg atcgttcccc ggcctttcca tatcttcttc tggataccgg catttatttg
     2521 ccataacgga tagatcgtag cttgtcccgc cgccattttc ccattataga aaccgataag
     2581 ttcagcgctc caagtccggg caaagctaaa ctgattcgag atcccgatat tcggtgtcca
     2641 tctcttattc acctttactt gataattctc cggtaaacga taccggttat agatcaagga
     2701 tgcgctgacg ttcacgttcc aaaatgaggt tagcggtaat tgggaggtac tgagccgggg
     2761 acctacgctg acgcgggaag agagattttc cggtgagaca taaacgacat agttcccttg
     2821 atccaaatag ctcttgataa ttacatcctt cgtataattg aaagcaagcc ccacccggaa
     2881 taaatcgcca tgtatatagg ccagttccag attatcggat aattccgggc gtaataaggt
     2941 gttaccttta tcatacgtat actcatcgtg gatatataca aacggattca ggtcccggta
     3001 attcggacgg acaatccgtt tgccataagt tagcgacaga ctattcccat tcctcaaggc
     3061 atactgaaca gaaagcgttg ggaacaagtg cgtataatga ttggtaaacg aggagtctct
     3121 ttgataagcg ttacccgatt gttcgccctc tatgcgggta ttttccagac gaagacctgc
     3181 ctccagactt atagaagaga atttggcgtc aagctgtaca tagcccgcgt ttatattctc
     3241 gtcatactga aaatcacaac tcaagtcatg gtccggttgc caagaatcac cttgtagccg
     3301 attataatca gcgttattat caatagagac gaaagaggtc ttagcgcccg catggaacgt
     3361 gaaggatttc gagaaaggcc acaccagatt cgcttgtccg gagtataaat ggattcctcc
     3421 atccatatcc ccaaacaagg tatcttggct attcaaatat tggtcttcct cgtatcgata
     3481 acgcaagtaa tccatagagg catccaagac cccaccatca gagttaaagg tatgtgttaa
     3541 acttaaaaca gccgtaaaat tatcctgcga acgattctga tcgttcaagg tgcgaagcga
     3601 acctccggtt tgcggagatc gcttaggaat ggatgagttc atatctccct caaccttgtt
     3661 acccgccaga ttaccatccg tcgaaaaccc gatcgtagtc ttatccgaca tttgataatc
     3721 gatcccgaaa cgataatagt ttgatgtatt cttccaagtt cgataggaag attgcgtcat
     3781 ctgcccggtc tccccttccg gccgccaacc ttccagatag tttctctcca catacagatc
     3841 atcgtaatca ttcttccggg aataggaata agagagatag aagttgaact tattcgttcg
     3901 cagattcagg gtagtagaag cgaaaccctc tccatattta ccttggtcat aactaccgtt
     3961 taccgaaagg ttcattcccc ttcgcaatat cttcttcgta cgtatatcga taataccgga
     4021 gtttccacta gcgtcgtaac gtgccgatgg ctgcgtaatc aaatcgattt tatccgtaat
     4081 ggaggcagga gtcgatttta agaggttgac aagatcttgc cccgataaat aggtaggctt
     4141 accatccatc aagatattcg caccgttttg accattcaag aaaatagtgc catcattttg
     4201 tatcacgact cccggcaaac tggtcaacac gtcgtagaca ttcccttggc tttgggtgat
     4261 agaggcatcc agcctataag tcatcttccc cggtttcatc tctaccgtag ggagcttagc
     4321 cattatcacc acctcctgta acttctggtc cgctatcgta tcgacctgtc cccaaccaca
     4381 aaaaggggta attatcaata gaactattat aaaaagattc ctgctcatgt cgtttttata
     4441 tcaaaattac atcagcagga atatccaatc aaattattgt gaccaacgga agtatccggg
     4501 ggatgaaagg taaaatctcc tacttttgcc ttctgaagtg aataacttgc ggcttgtcga
     4561 gtgaataact aacgagtata cccagtgaat aactaacggc tttagaagtg attagttatt
     4621 cacttctaaa cgctttttcc agctgttgat caagcaaaat tctcatttcc ataaagtcat
     4681 ccacgaagag gcttttctgt ctttttgagt agtattagag cttttccata acatctcatt
     4741 tccacaggaa tcacaagata aaggagggga gataacaata aacagtgctt ttccaatgaa
     4801 aaagaccgtt ttcgatacac attaggcgac aaaagcctac acatacggtc gcgttaagca
     4861 acgccagtag tgccattggg cattataagc agtcgcaaat agggttgtaa gtagtcgtga
     4921 atgggcactc ttacctcctt atagccctat cgtaacaccg tttttccctc cttttgctcc
     4981 atcggatatg aattacgatg aattattttc gctagaacaa aaggccattt ttcagcattg
     5041 ctctatcaat gaaccgattg ctgatttatt ttttcaaatt caagcacaag acgtacctta
     5101 gcccggaaaa atcgattctc cgggacttcc gattacaaat tgtcaatcct aacaaattgt
     5161 catatccttc gatcgtcttt ctcgaaatct ctcaaagatg attatcaatt caataaaaaa
     5221 acgtattttt gtcacataca atctataaac aacccaagat atggaagtga cagtcaagaa
     5281 agtagaaatt accttaccgg aggtagacat ggccttgctc aaagaactgg ccaagaaatt
     5341 cggttggaat atcggcagga agaagtccgg tatagagaag ggactggagg atatcaaggc
     5401 cggaagaaca cacaaagcga aaaacgcaga agatatgttt caacaaatcc ttggttgacc
     5461 catgtaccga ttggaataca ccacgaattt taagaaagat cttaaaacgt gtaagaaaag
     5521 gggattagaa cttcatctac ttcaaagggt tatcgatatt cttcaagaaa ccggtacgct
     5581 ccccaaccaa tatcgccccc ataaactaag cggtaaattt gagggcctat gggaatgcca
     5641 tattaaaagc gactggctct taatatggca acaaaacgat accgaactgg tcttgatcat
     5701 gaccgatact ggtacgcatg ccgacttgta ttaagtcatc agcggttatg cttgatcaga
     5761 ttcataaact cctcgcgcgt cttagcttgt tggaaaaagc ctgtgaaatc agaggtagtc
     5821 gtcaaggaat tttgtttctc cacgccacgc atctgcatac acatatgctg cgcctcgatc
     5881 acgaccatca cgcccaacgg gtccaaggtc ctctggatgc aatccttgat ctgcatcgtc
     5941 atacgctcct gtatctggag gcggcgggcg aagatatcca ctaccctagg gatcttgctt
     6001 aagcccgtaa tatatttctt ggggatataa gccacgtggg ccttgccaaa gaaaggcaac
     6061 atatgatgct cacaaaggga gaagaaatcg atatctttca cgataaccat ctgtttgtaa
     6121 tcctcttcct gaaacatggc ggaacggagt accgcctccg gatcctcatg gtatcccttg
     6181 gttaaaaact gcatcgcttt cgctacacgt tccggcgttt taagcagacc ctcacgctcc
     6241 acgtcctcac ccagcaaacc caatacttcc ttataatggc cggccaaagc ttcccgggca
     6301 catagcgtct cttcgtttac ttctgacatc atctttaatt taggggaatt tttatctctt
     6361 ctcgtacgat atacatttcc tttccgtatt tcgggaaagc gcccatcaac aggcgcatca
     6421 tatgataagc ctcctcatgt gagcggaaat cccctacacg caatttccag aacggggcgt
     6481 tgtaagtgac ataggtcggg acctcgggaa aaagctcctt gatctccttc tccttacgaa
     6541 aagcctcgtc tttcgagacc cgttggttgt taccggaaaa tacctgcgta cgataccctt
     6601 gtaccttcaa gaaggtaagg ctatcggtcg tctccacgtt cgctccacgc atacgctcgc
     6661 ccaccatctc gccaatagcg gcggattgat tgataacgac ctcgcctttt cccaaaccgg
     6721 atctccgcaa tgcgtcgaat atggtcgaac gctcaccttc caacgccgtc tgagcgaata
     6781 aagatgaagt accggccatc aaaaaggcaa atagcaataa gatacaagga attcttttca
     6841 tcgatatact attaaaaggg tatctttccc ctctgaagag ggaaaagatg ccttcttatt
     6901 atgaattaat taaaaagcct cgataatcgg catgaatttg tcaacggaca aagaagcgcc
     6961 accgatcaaa ccaccgtcta cgttcggttt agcgaacaat tccttcgcgt taccggcgtt
     7021 gcagctacca ccgtaaagga tcgtgcagtt atcagctacc tcattgccat atttagcggc
     7081 caaagtagcg cggatgtgag cgtggatctc ctcagcttgc tcagcggaag cagtcttacc
     7141 cgtgccgata gcccataccg gctcgtaagc caagatgatc ttaccgaaat cctcagcgga
     7201 aaggtcgaac aaagaaccag cgatctgagc gtctactacc tcgaagtgct taccggcttc
     7261 tctctcttcc aaaacctcac cgatgcagaa gatcggagtc aaaccgttag ccaaagccaa
     7321 ctcaaccttc gtcttcaaga tttccggagt ctcatgataa taagcacgtc tctcagagtg
     7381 gcctaagatc acatatttcg caccagtaga agctaccata gcggcagaaa cctcacctgt
     7441 ataagcacct ttttccttgt cagcgcagtt ctcagcggca acaccgatct tgtttgtatc
     7501 gatagcggca gcaacgcttg ccaagtgagt gaacggagta ccgatgatca catcgcaatt
     7561 cggagtctta cccttcaaag cctcgtccaa acctttagcc aaagcaagac cttcagcaag
     7621 agtagtgttc attttccagt ttcctgcaac aatattcttt ctcataactt aataatttaa
     7681 atatgtaata caaataaatc tctattcaga ttcttttcct ttccggcgac ggcgattgcg
     7741 caaggcatcg tatccccaaa ccagcaacaa aggtacggta aaacttaata ggttggttat
     7801 tagccgggca tcttctttcg ctttccagtc ggtatttcct tccagatagc cgtttacgat
     7861 cgttttcagg tcttcttcct gtggaatatc gttgtaatgc cacttcatca agatcgtacc
     7921 tttcttcagc aagaccaatc ccgggttgga gcggatgatc gttttcaaaa ggacatcatc
     7981 ggccataaga aacggatact cggcaccggt attatcactc catgtagcga tagcctcggc
     8041 ggaagaaccc gtcacgcaat aaaagcccaa accgttctcc aaggcgtaat cgtatacatt
     8101 gttgatctcg tcaatacgct catcatccgc attctccaga cggggggcga tcaaaagaaa
     8161 gagacctttc gggtcgttca gcaactcatc agtcacgtct gcgtcattct cattataaat
     8221 atgaaatgtg gtaacggggg gaacgtatcc ttgtttgatc agcttggtct ttgaatccac
     8281 gaaagtccac gtgctatcat cggccggggc gttctccaaa gaaaattctt tctgtacgcc
     8341 atccctctcg taaataaaag aatacgcata ttcatcctcg ggcgcacctt ccggtatcga
     8401 catcaaggca gggatattcg cacccaactt atagggacgg aaatccaaga tcggcaaatg
     8461 attataattc cggtaagcga aaccgatagc gaagacatat gaccacaaag ccacgaacca
     8521 gtaggcatgg taggtatagc cttgtaaaag ccgctgatta tggatgaaca cgtaaatagc
     8581 ggcggccaaa agtacgacat tcttatagaa ggtctgccaa ttactgatca ccaaggcatc
     8641 cccgaagcaa ccgcaatccg atacgggatt gaagatcgcc agatacagcg tcagcggcgt
     8701 catgaaagac atcatcagca aggtcaagaa ggtcgtatac cgccggtaca cccctaatag
     8761 catacagaca cccagcatga attccagagc ggacaagttg aaggagatca ataccgtaaa
     8821 aggttgcagc ttatccagcc caaaggaagt cagatagtcg ccaatcttaa tggctcctcc
     8881 catgggatcg acagccttca ccgtcccgga gaagataaag actactccca gtaacaggcg
     8941 gcagacctct gcgatcactt tctttacggt ttccttatat tccatgtagc tcactcctca
     9001 ccaaactcca gcttgatcaa accgaagagg gcataattaa tcatatccat gtagttggcg
     9061 tccactccct cagaaacgag cgtcttgcct ccatgactct cgatttgctt agtccgataa
     9121 atcttcatca aaataagatc cgtatacgag ctgatacgca tgctgcgcca cgcctcatca
     9181 taatcatgat tcttggcgta catcagttcc ttcgtctccg caatgtattt atcgtataat
     9241 tccaaggctt tctctatcgt gatatcggtc gtatccgcaa atcccaacgc caattggatc
     9301 aagccgatca caccataatt aacgatagcg ataaactccg gacggattcc ctcgtccacc
     9361 atgctcgtcc ccttgatctc caagctacgg atacggttcg ccttgataaa tatctgatcg
     9421 gtaaccgact gggggcgcat gatcctccac gacggcccgt aatctttcaa cttcttctcg
     9481 aacaactccc ggcacaggga gatcacttgc tcgaattgtt cctttgtatt tggcatacta
     9541 tcctagatta tacccgcgaa tataggaaaa aagacgtaga tgttctcgaa aattcaagac
     9601 aacaaaagct aataagataa atgaaaagag gttacaacaa aaaggagcca ctttataagc
     9661 ggctcctttt cgtttcctta catcttatat atcgttatga acagcgtaat gagcgtccta
     9721 aacgcaacac ggtagtcttt gtgataccgt tcaattcgca gagtttacta acagaagtac
     9781 cgtatctttt agcgatagcg ccaagcgtat caccggattt aatacgatga taaaccgaag
     9841 tagcctccac atcattcatt gtattcgtgt cttctcctaa agaagcggta gcggaagaac
     9901 ttgcctgtac cgtgattttc ttagaagatg cggaagcagt cgatttcttt tgagtttgag
     9961 cttttggagt cgctttagcc gcggtttcca caccggcact acaacgaatg gactggccga
    10021 tacgtaacat agaagtagat ttcaatccat ttaaacgaca aagctcattc actgtcgtac
    10081 catatatacg tgcgatttta cctaaggtat caccggattt tacacgatgg tacaccatct
    10141 gactattgga agatgtatag atattgctct tacgtccgtt aatcttgacg ttacgaaaca
    10201 catattgatc ctgatgaggt attgagttct cgaagtcaat aatatcagcc gggttaatag
    10261 cctgtccaag aaaacgagtc tcaaaatgca aatgagatcc cgtagagcgt cctgtatttc
    10321 cccctaaagc gatcggatct ccagcccgta cgatatcgtt cacacctact aagaatttag
    10381 ataaatgacc atatacagtc tctaaaccat tcggatggcg aatcacaaga taatagccat
    10441 atcccctacg ctcgaaattc ttgatacgca ccttgccgtc aaacgccgca cggatcgtat
    10501 ctccaatttg cactttcaag tctatcccct tatgcatccg tctacggcga ggaccatact
    10561 ttgaagtgac ccttgtcata gagtccatag gcaagacaaa agtagaacaa tcgattacgc
    10621 aagaatccgg catatctacc tttttacccc ggaaaggatt cacccattca tttgtccatt
    10681 cgccatataa ttcatcggca gggaacatca agttctctct cgcctccaac tccgctttct
    10741 cattaatctc cgcaagctcc ttcaaagcca tatctttctt aaagccaaca cggtcagcca
    10801 ttaactcaga tacacgcttg tccataagtt tgtgggttgg atgattggga gtctccggag
    10861 tttccggttt caccgggttc tccgcattag cagtcgatac catcacagcg gcacaacaaa
    10921 tgaatagaaa tgtccttata ctcatttttt gataactttc attcttataa ttcaggataa
    10981 aacggcaata cccgacatct ctgcctgatt gtcaacttgt caaagttcgg aaatttgaat
    11041 aagccgacaa aattgattaa cgaaaaattt ctgcaatgac tttgaataaa agcaaaacaa
    11101 gcgaataaac aagctaaata tcaaagactt acaaaacaat atgtttcaca acatattagc
    11161 taatcattcc ccaatttatc ttccttgtga acagagtttt gagcctttcg ctcaatatcc
    11221 ggtgctgttc ggacaataat tcggggtctt cgtcaagaac tccttgagcg atatcccgcg
    11281 catactgaag tatttgtcca tcggccgcca agtccgctat tttaaggtct atcccctcgc
    11341 cactttgtcg ggtaccttcc aaatctccat gtccccggag acggagatcc gcctcagcga
    11401 tctcaaagcc attcgtactg ttcaccataa tctccaatcg cttacgagta tcattactta
    11461 gtttatagga tgagaccaag atacaatagg attgttcagc accacgtcct acccggccac
    11521 gaagctgatg aagttgagag aggccgaaac gttcagcact ctcgatcacc atgacggatg
    11581 cgttcggcac gttcacgcca acctctataa ccgtagtagc catcaagatt tgcgcctcgc
    11641 cggagataaa cttctgcatc tcggtatcct tatccgccgc tttcatacgg ccatgtacca
    11701 tacatacctt atattcaggg aaaacctcct tgaacgtctc aaaaccggcc tccaagtctt
    11761 tataatccag tttctcattt ccttcaatca acggatatac cacataaacc tgacgcccct
    11821 tttgtatctc tttccgaagg aactcataca attgcgcctt tttattatca tagcgatgaa
    11881 gcgtttgtat cggtttacgt cccggaggta actcatcgat caccgataca tccagatccc
    11941 catacaaagt catcgccaaa gtacggggaa tcggggtagc cgtcatcacc agcacatgcg
    12001 gcacgatagc gttcttcatc caaaggcgtg agcgttgctc cacaccaaaa cggtgctgct
    12061 catcgataat cgctaatccc aacgaagaga aaaccaccgt ctcctcaatc aacgcatgcg
    12121 tcccgatcac gatctggatc tcaccgctgg caatagccgg taatatctta tcccgctcct
    12181 tcttcttggt agatccagtc aaaagagcga ccttcacgtc catatctttc aggaatccca
    12241 tgatcgtcgc ataatgctgg gtcgccaaga tctcggtagg agccatcata caagcttggc
    12301 aatgattatc tatcgccaat agcatagaca ataagcctac caaagtcttg ccactcccca
    12361 catcaccttg cagcaggcga ttcatttgcc gcccgctacc catatcgatc cggatctcac
    12421 ggactacccg cttctgggcg ttcgtcaact caaaaggaag atactcttta tagaacgtat
    12481 tgaaataatg gccgaccgtc gggaatatga tcccttttag cttcagtttc cgaacactag
    12541 cagtacgtaa tatatttaat tgtatgaaga aaagctcgtc aaacttcaaa cgtaactggg
    12601 catcacgcaa cttagcggca gattccggga aatggatatt ccgcatcgcc tctgtcatag
    12661 acatcatatg gatccgtttc aatacgtcgg gggaaagcgt ctccggaagt tcccagttca
    12721 gccagcttaa caacgtatat tgcaggttct ggatcgcccg ggaattcaag aaagatttct
    12781 tcattttctc cgaggtatta tagaaaggag tcaagccatt cgccacttga tcagcttgct
    12841 ccattgagtc gatatccgga tgcggtatgt tataggtatg cccgaactcc gtaggctttc
    12901 cgaaaactat atactcagta ttgggacgat acttatccgt cacataattc aagcccttga
    12961 accaaaccaa atcgatcgtg cccgtaccat ccgagaactt accaaccagc cgtttactcc
    13021 gcccctcgcc tagcgtatcg aaatagagaa tctggccttt caactggata taaggcatat
    13081 tcccgctgat ctcagctact ttataaaacc ggctgcgatc tatatattta taaggaaaat
    13141 aaaagagcaa gtcctcatac gacgatatcc ccgcttcctt ttgcaggata tccgccttct
    13201 tgggtcctac tcccggcaag tacgtaatcg atcgcttatc aaggtccagc ataacgtcta
    13261 tgagttttta gggtttaccg ggcaaacatc gcttccgcta ttaacaaatc aaagggcgtg
    13321 gtaatcttga tattctcacg atcaccggga accgtatcaa tcgcatgccc catcgcctcc
    13381 accacggaag cgtcgtccgt aaataaagac gaataaggtt gctcataggc ttttgtcaat
    13441 aattccagaa ggaagacttg cggggtttgt acagccatat agcgggaacg gtccaccgga
    13501 tggctccctt tttcatctgt ctcacgcagg gaatcaatca tcggaacaac cgggataacg
    13561 gctcccgtga cagccgcttt atcaaagcag gcctcaacaa cctccggaga gacgaaagga
    13621 cgaacgccat cgtgcacagc gaccaaactc agaccgctat cctcctcccc cttccgacgc
    13681 ctctccgcca aaagccaatc caacccattc ttaaccgaga agaagcgagt atctccccct
    13741 ttcacgatcg catgcgggac cttgcagccg atttccttgc aaagcatatt ccaatacggc
    13801 tgatgatcct ccggaagcac aaggattata cgtgcggaag catcccaacg atgaaaagcc
    13861 tctaacgtat gcatcaaaag aggtttcccc cgcataggaa taaactgctt cggcagatct
    13921 ccacccatac gaagcccttt acccccggca acgatcaaga cgtacttatt catcaatcca
    13981 attcctccaa aactttttta acttcctcat ccactttata cagcttctcc ttgcaaagct
    14041 tgatcagacg agtagcttct tttaccttct cggacaggat atcgacatcc aagtctccat
    14101 tctcgatctc agccacgatc ttacgaagtt tctcgatcgc ctcgttatat gtttcttctt
    14161 tcttcgccat attaattatg tatttatcgg acggttataa aaccaccctc tatggtttga
    14221 taatactttt tatttcacca tcgatgaagc gagtcgtcag ttcttcgccg gctcgcaaat
    14281 cagaggcatg tttgataatc ttgccatctt tcaaggctaa gctatatccc ctcttcaata
    14341 tataatcagg agaagccatc ttgataaact gctccgtaag ctggataaaa cgcccactct
    14401 cggaaagttt agaggtaata ccgttccgca agcgaagttc cgtattctca agcaccgact
    14461 ggcggcgtga taacaaaccc gatgccatcg caggtaaacg gctcgctatc gtttgcagtc
    14521 ccgaacgatt ccgctcgatc cggcttgtca cgatagaagg gaaacgggtc gctaccaatt
    14581 gtaaatagtt tttctgtcgg gatagaatat ccatagccaa taaactcacg tcttgacgca
    14641 aactctccaa ctcctcacca acgctatcca ttcgggaaat aaggaactcg gcgacagcgg
    14701 tcggtgtctt catccgggta tgcgctacca aatctacaac cgtatcatcc cgttcgtgcc
    14761 cgatacccgt gataatcggt aaagggaatt gagcgcaatt cgccgccaac agataagaat
    14821 cgaagctatt caagtccgag gtagccccac ctccgcggat aatcacgacc acatcaaaaa
    14881 gatcttgatg ttgataaatc cggtctaaag ccgctattac agaagcctcc gtccgttctc
    14941 cctgcatcaa ggcggggaat aatttggtat agaacggata acctccttta ttccgtgtca
    15001 actgattcat aaaatcctcg tagccggcag ccgtcggaga agtaatgata gcgattctcc
    15061 taggaagtag cggaaaaggc aattccttat tcagtgtaaa gaccccttcc tcctgcaatt
    15121 ggcggataat ctccatacgc ttacgcacca tatcacctaa cgtataagcc ggatctatat
    15181 caagcaccgt aagactcaat ccatacaact cgtggaactc aacagacacc ttcaccaaca
    15241 ctttcaagcc ggaagcgaac atctgaccgg tctccatctc gaaataaggt ttcaacatac
    15301 gaaacgtctt cgcccagata gaccctcgta ccttggccac caattgcccg gtctgcacat
    15361 tcttctccac aaactccaga taacaatgtc cggaagaagt attcacccgc acatcgctca
    15421 tctccgcacg cacccagcaa gtctccggga aagccctcga caacgcaccc cgtatgcggg
    15481 tattcagctc taacaaagat agagcctctt tctcacccga taagttattt agattcggcc
    15541 gcatatttac gctcttgttt ataagctttg tacacatccg ggatgccata tcccaactca
    15601 gcgtccggtt gctcaaactt actgccgaaa cgctgcaaaa gagagattat atccttattc
    15661 gtcagactgg gaaacgcttg ccatagacaa acacccaacc ccgctaagat cggcgtagcg
    15721 aaagaggtac cgttcgcgta acggatattc cccgtaggat ctatcacgca acagcccgta
    15781 cccaaggcaa ccacatccgg cttcacccgg taatccgccg taaagccaac agaactgaaa
    15841 ttacttttct tcttacgatc cgtgatagcg cccactgtca atatatccgg ggcatccgct
    15901 ggaaaggtta tctttcccca gctaccgccc ccctcgttgc cggcgctact aaacaacaag
    15961 atcccttttg atgaagccat cttagcggca cgactgatca aggaagtcct cccgtccaat
    16021 tgatcttgat gatagttcag ggcctctaca tcaaaagaga aataccccaa cgaagaagag
    16081 accacatcca ctcccacgct atcggcaaat tccatagctg ccgtccaata atcctcctcg
    16141 atgggaaact ccgaacggct atcctcgctc tttatcagcc aatattcggc ttggggagcc
    16201 gtaccgacca tcaagcccgg cgcatcagcg gccaagcaag ataagacctt cgtcccatga
    16261 tcatccccga tgaaaacgct tcggccgggg aaaaccacgt tatgcgttcc taataaccgc
    16321 aaggaatcaa atacgctgat ccgatccacg ttcatgaaac cggcatcgac cacggccaca
    16381 cgcataccct tacccttaaa gcccgcctca tgcaatttga taccgttcag catcttgatc
    16441 tgctcctcgg cataaccgta aggcgatttc tccggtttat ctattggcat aaaccgtgtc
    16501 gtatcattct cctccctagg aatatcgatt tcctcgtcac ctttccagac ccatttcacg
    16561 gaatccacga tcgggaggcg caagagacgc tcagcgacca agctatccgg actggacacc
    16621 acgaccgtag agaaccattt gctctccagc accggttttc ctccattggc ggacaaggta
    16681 tccagataag cttgagcgat cggcaaatcc gattccgaca ccgatatacc ttgccggttc
    16741 cgtcgctcaa cagactcctt ggaaagatat tcctccgggt tatccagcgt ataaccggaa
    16801 tcccctttat ctttcaaata cacccgaaaa cgaaaacttt cccccgcatg tactcccaaa
    16861 gaaaacaaac tgaatacgaa aacgaatatt cctatatatt tactcataga acctcacaca
    16921 attacgaatt acaaagatag atgataccgc cgaataaaca aaaaagcccg gcactggaat
    16981 aggccgggct catgtataat tcttcgtctt attcattgat attacagata gggatctcac
    17041 gtttaacact ttggcgtaaa gaaatcaagg tctctgtagc cgtaacaccc ggtatctctt
    17101 gaatcttgga gttcaaaagc tccatcaagt gctcgttatc acgggcatac agcttgatca
    17161 gcatcgtata cggacccgta gtgaaatggc attctaccac ttcgggtatt ttctcgaatt
    17221 ccgggacaac atccttgtac atagatccac gctccaattt cacgccgata taggtacatg
    17281 tattataccc caatatttta ggattgatgt gataccctga gccaacgatc acattcatat
    17341 caatcatgcg ttgaacccgt tgatgaatag ctgcacgaga tacaccgcac tcctcggcaa
    17401 catctttaaa aggaatccta gcattctttg aaataatgtt caatatctgc cggtccagtt
    17461 tgtctatctt ctccatttta aattcgcttt attatatgca ttcagattta atgtatcaaa
    17521 agtatataat aaatttgaat catatatcat tctgaaagaa aaaagtaatc aataaataat
    17581 aaaagcgggc aaaaaatgct ttttagcata atttgcccgc ctattatctt acaaacgttc
    17641 cgtttctatt tcttcgctac ttattctttt acgatgtcaa gcaactcaac ctcgaacttc
    17701 aatacgctgt tcggtttgat atcttgtcct gcgccacgtt cgccataagc caactcagcc
    17761 gggatccaga agatatattt agaaccgacc ggcatgatct gcaagccctc agtccagccc
    17821 ttgattactt ggccaacacc gaactcagcc ggctcgccac gatccacgga gctatcaaac
    17881 ttagtaccgt ccaatagagt tccggtataa tgaactttta ccttatcggt agcggtcggc
    17941 ttcgcgcctg taccttcttt ctctacctta tattgcaagc cgctctcagt cgtgataacg
    18001 ccttcttttg tcttattctc cgccaagaac ttatcgccct cttcttttgt cttcttagcc
    18061 tcgcgagcct gagcctctac gaagtaagtc tgcaaatatt gttgagcctg ttgcggattc
    18121 atcttcatcg cagaagaatc ccctttgata gcttggataa aaccagcgat caaatcatct
    18181 acgttagcct caccacccgg caaagtcttt aagttttcct tataaccggc acctgtgctg
    18241 ataccaatag cgtagcttgc gctatcgata gaagtcttca agctcgcgct tttgtgagaa
    18301 tcaccgcaag aggtgaaaga tgcgcccatt gctacaatca ctgtagcgac taatacactt
    18361 aactttttca tttttcttta actcttatat attatttttc gatatctaat aactcaacgt
    18421 cgaagatcaa cgtactattc ggctcgatag cctcacctgc cccacgctcg ccataagcaa
    18481 ggttagacgg gataaacaat ctccatttag aaccgaccgg catcaactgc aaagcctcta
    18541 cccatcccgg gattacctgt gaaacaccga atacggcggg ctcgcctctc tgtacggagc
    18601 tatcaaacac ctgaccgttg attaacgtac cgtgatagtg gcattttacc ttatcgttcg
    18661 ccgtaggttt agcgcctgta ccattcttca gcacctcgta ttgcaaaccg ctaggcaact
    18721 ctaccacacc agccttatgc ttattgatag aaaggaactc ctcaccggct ttcttattga
    18781 tctccagttt ctcttgttga agcttcatga agtaatcatt gatcacttgt tttgcctcat
    18841 cataactaag agcaggtttt gcctctgtta agacgtcatt caatccctgt acaaaatctt
    18901 ccacttgaag atccttgatg cctgagttct ggaaattatt tccgatactt aagccaagcg
    18961 cataacttac tttatccatt cttttttctt gttcaactaa ttataagcca caaaagtaat
    19021 gcttttaatc gtataacagc attttgtaag aactttttat ttcattcaaa gctttttacg
    19081 aaataaagtc gtaacttcgt aactattaat atatacatct atacattaaa caagtaacag
    19141 atgaaaaagt tagtcatact aaccggagcg ggaatgagcg cagagagcgg tatctccact
    19201 ttccgtgact cggacgggtt atgggagaaa taccgggtgg aagatgtcgc cacgccggaa
    19261 ggcttcgccg ccaaccctaa attggttctc gacttctaca accagcgcag aagagagcta
    19321 ttgaatacga aacctaacgc cggtcacctc ggccttgccg ccttggagaa agatttcgac
    19381 gtacggatca ttacccagaa tatcgacaac ttacatgaac gcgcgggtag cagccacgtg
    19441 atccatctgc atggagagtt gatgaaggca tgctccgtaa gggatctgga cacgacctac
    19501 aatctatcgc cggagaaccc ggatattcat ctgggcgaca aggaccctca cggaaatcag
    19561 ctacgtcctt tcgttgtatg gtttggagag gcggtaccca tgatagagcc ttccatcaag
    19621 ctggtggaag attgtgatat tttcgtgatt atcggtacct ccttaaacgt ctaccctgct
    19681 gccggattac taaactacgt gcgccggggc caaccgatct acttgatcga cccgaaagat
    19741 gtacgtactt atcgcgacga catcgagcat atacaggccg gagcctcgga aggggtcaag
    19801 aggctgacgg agttgcttac gcagaattaa acaattcata cactcattag gtctgacgaa
    19861 ggcaagtata aacacgaagt ccttggcatg cgaacacatt gccaaggact tgtcttttta
    19921 tccgcttcca tcctcacgga agtacttacg gatgaacttt aatttattac tttagtatta
    19981 atattaatcc aattcccgcc tgttcatccg tcacggatta cttggatcga tacccgcacg
    20041 ggaatcgtat gattatctta tttcgtttat ttcttatttc acgattgcct ttacagcctc
    20101 ctcaccatca acagctacag ctacgataga tacgccttca gcgttagtgc cttcgataga
    20161 tgttaccata tcctcagcgt cagtcttctg gtatgcgttg aagatcaagg caccgtcaga
    20221 accagtctta gcggcattga attcagagtc gccacgagtc aataccaaac aaccgttttg
    20281 catcttcaac catgcggcgt aagaatgtac gcacgtacat taaaagcagc ttattcccca
    20341 cttccaataa tctatttatt atttactctc aacacagact atttcgctct aagttattta
    20401 tctaatgccg gaatactttc agtgtaagcc tgttttgaga caggttatat tcagcaagaa
    20461 tccacctgtc agtaaaacaa cagttataca atccttttga ctgaaataaa gcgcatatcg
    20521 tgacataggc tattcgtaaa agaggcaaga taatgagaaa aaggaggttg taagcggcgt
    20581 tttatgcggc aaagtactac tttttacaca cgagtatcga caaaagccta cactatcggt
    20641 cgtgtttggc aacgccaata gtgccgttgg gcatcgtgaa tagtcaagaa tagggtcgtg
    20701 aactatcaag aatagccatc ataaccctgt cac
//
LOCUS       DBMDTB010000075        20732 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_859_length_20732_cov_12.572294, whole genome shotgun sequence.
ACCESSION   DBMDTB010000075 DBMDTB010000000
VERSION     DBMDTB010000075.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 20732)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 20732)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20732
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_859_length_20732_cov_12.572294"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..300
                     /locus_tag="ACZPB4_11980"
     CDS             <1..300
                     /locus_tag="ACZPB4_11980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrilase-related carbon-nitrogen hydrolase"
                     /protein_id="HIR1098963.1"
                     /translation="ARAYDNAVYVVFSNPIGRDYNEIKNGCSMILDPFGDIVAECRKL
                     GDDFVIATAIPEKLRQAGGYRYRNARRPELYADIIGQPHESNQKVAWLTETTNSK"
     gene            306..1493
                     /locus_tag="ACZPB4_11985"
     CDS             306..1493
                     /locus_tag="ACZPB4_11985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF418 domain-containing protein"
                     /protein_id="HIR1098964.1"
                     /translation="MQQTTISKSPRVEVVDALRGFAVLAILLVHNVEHFIYPVYPDPA
                     TLPGWLNVLNEGVFTVVFALFAGKSYSIFALLFGFTFYIQYSNQQAKGKDFGYRFLWR
                     LLLLTIFATLNAAFYPAGDVLLLYAIVGVVLFIVRKWSDKAVLITAIIFLLQPVEWYH
                     YIASLFNPDYQLPNLGVGEMYSEMAEHTKRGDLWNFIWQNVTLGQKASLLWAVGAGRY
                     VQTCGLFMLGMLIGRKKLFIPSEENSRFWIKTLIITAIAFGPLYQLKVLLMDTADSAT
                     VRQTAGVVFDMWQKFAFTFVLVASFVLLYQREAFKRFTSILRSYGKMSLTNYVTQSFA
                     GALIYFPIGLNLAPYCGYTVSMFIGIAFFFLQVRFCKWWAERHKHGPLEGLWHKWTWV
                     GSK"
     gene            complement(1557..2093)
                     /locus_tag="ACZPB4_11990"
     CDS             complement(1557..2093)
                     /locus_tag="ACZPB4_11990"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009016569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIR1098965.1"
                     /translation="MNKEIKIRPEQENDFQAVREVVELAFRNVEDSDQSEPYLVERLR
                     KTDAYIPELSLVAELNGEIIGHLMMSKVEIVSEDQSVISLGLAPVSVVPKYQRIGVGS
                     ALIREAHKRAGELGYKSAVLLGHKDYYPRFGYKRAIDFGIEFPFDVPSEYCMVVELAP
                     EGLKNVHGMIKYAKPFME"
     gene            complement(2143..3237)
                     /gene="porN"
                     /locus_tag="ACZPB4_11995"
                     /gene_synonym="gldN"
     CDS             complement(2143..3237)
                     /gene="porN"
                     /locus_tag="ACZPB4_11995"
                     /gene_synonym="gldN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0071806 - protein transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type IX secretion system ring subunit PorN/GldN"
                     /protein_id="HIR1098966.1"
                     /translation="MKHLYYIAALAATFLTAMPLHAQEEAENDATQQQQTRRRSPQAS
                     RGERNDKKDTGLPELTVRAQDMNERLTQEIGNARWMRIIYRQVDLMKEQNAPLYYPTR
                     PMNGQMNLFSVIFQLLGENKIKAYEYLDGYEEFDEAHLINFKDLLDRFYILYEEIPGR
                     AGEEPTFVINESDIPAADVRSYYVKEAWYFDQNNSAFDVKILAICPILTSTGDMGETT
                     MPMFWLPYENIRPYISNSYIMTSNMNNAMTFTMDDYFRRRMFEGDIIKTQNLMNLPLQ
                     AYCPTPDSLKNEQARIEGQLTGFEKSLWYQPDTTQVAVDSKAAKKARKSAARGKGTTT
                     KEPASEKKAPTVKAPKAEKSAPVRSVRRRR"
     gene            complement(3248..4816)
                     /gene="porM"
                     /locus_tag="ACZPB4_12000"
                     /gene_synonym="gldM"
     CDS             complement(3248..4816)
                     /gene="porM"
                     /locus_tag="ACZPB4_12000"
                     /gene_synonym="gldM"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IX secretion system motor protein
                     PorM/GldM"
                     /protein_id="HIR1098967.1"
                     /translation="MAGISNNPNSPRQRMINLMYLVFIAMMALNVSSEVLDGFELVEG
                     SLRTSIDNSSRRNKIVADEMEAYYQENPQKVGEWALKAREVKRASDSLYTYIQDLKIR
                     IAKVADGENANVNSIEHKDDLEAASRVMLSPVSGEGKKLRAEIDKYRIWMGGFIEDSA
                     KTAVLEANLSTTPPHKAGINTRTWEEALFENMPVAAAVTLLTKMQSDVRYAEGEVLSN
                     LLNSVDVGDYRVNQITAQVIPESQIVMRGSQYKANIVLSAVDSTKRPTIYVNGKELPY
                     ENKGVFTVNTGAAGTFPIKGYIEMPNSDGSIMRRDFESEYFVTEPTATVAPTLMNVLY
                     AGIANPMRIAVPGVPSGNVTATMTNGTLTRSKDGWEARPSKVGTEAVITVNARMADGR
                     NIEMAKTTFRVRALPDPLPYIEYKDQNGNVRKFKGGMIAKRSLVEADGILAAIDDDLL
                     NVKYTVLRFELTFFDSMGNAIPEVAEGTNFSQRQKNYIRNLSKGKRFYITRVVAKGPD
                     GIERTIPTIEVIVN"
     gene            complement(4823..5914)
                     /gene="porL"
                     /locus_tag="ACZPB4_12005"
                     /gene_synonym="gldL"
     CDS             complement(4823..5914)
                     /gene="porL"
                     /locus_tag="ACZPB4_12005"
                     /gene_synonym="gldL"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IX secretion system motor protein
                     PorL/GldL"
                     /protein_id="HIR1098968.1"
                     /translation="MGKYRRYKNRLEMFLSSERGKRVLNFLYSWGASIVILGALFKLL
                     HIPYANQILFVAMITESIVFFISAFEHPNKEYHWEDVFPVLKSKNPMDRPDFTGTPIS
                     TMINSTDNVEDDEIAGGINIGSAASKANAQRGGSLNIAGNLDVTEEDTKNLSESIKKL
                     SGAAEQISKMAELTEATQKYLEQLSGMSENMERFSQVTNSLTNVSDTLLNSYKSITDN
                     SDGINQNSRGYVHQMEQLNRNVSGLNTIYEIQLKSISSQIESIEHINSGLNRIREMYD
                     GSVVDSSVFRNETEKMTRQLAELNQVYSRLLQAMTVNMGYQQPAQPQQQPQQPMYQQP
                     QQPGYQQQYQQPYGYQQPQQAPYTNNPMK"
     gene            complement(5966..7393)
                     /gene="porK"
                     /locus_tag="ACZPB4_12010"
                     /gene_synonym="gldK"
     CDS             complement(5966..7393)
                     /gene="porK"
                     /locus_tag="ACZPB4_12010"
                     /gene_synonym="gldK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005633367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0071806 - protein transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="T9SS ring complex lipoprotein PorK/GldK"
                     /protein_id="HIR1098969.1"
                     /translation="MKKVLLVLVTVALLTSCGKSLRSAGGEVTGVRSVAFNEPAPYGM
                     VLVKRGSFEMGPADKDSLWGIMPETKGVSFDAFWMDQTEVTNAKYRQFVYYVRDSIIR
                     ERLADPAYGGNDLFKITEDRYGEPVTPHLDWNRPIPWRRANEDEQRAIESVYYTNPVT
                     GEKGLDPKQMIYKYEWYDYTAAALRKNQLNPADRVRNTDIQVDPNEVVMISKDTAYID
                     DEGRVINETITRPLSSEWDFLNTRIVNIYPDENCWVNDFKNAYNEPYTRMYFSHPGYD
                     DYPVVGVSWEQATAFCVWRTNLYKESLSLPPGQLVEPFRLPSEGEWEYAARTGKNENK
                     FPWSTDELQDSKGCFLGNFKPGKGNYTEDGHLITSRVGSFAPNEFGLYDMAGNVAEWT
                     STSYSESGPSQMSDMNPDLRYNAAKNDPYAMKKKVVRGGSWKDVSQFIRSDMRTFEFQ
                     NESRSYIGFRCARTQIGFSRSKGKK"
     gene            complement(7397..8344)
                     /locus_tag="ACZPB4_12015"
     CDS             complement(7397..8344)
                     /locus_tag="ACZPB4_12015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008777736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PorP/SprF family type IX secretion system
                     membrane protein"
                     /protein_id="HIR1098970.1"
                     /translation="MRRRLLSILILLCTCAGIVRAQYDARLSQYFMAKPYYNPAVAGA
                     TEDLNILALARLEMIGVHGAPKSFFITADMPLTLGKTNHGVGLVVFTEAIGLFQNTHV
                     GAQYAYKYKLFGGVLSGGLQIGLVNQSFDGTKVIKVESEYHQETDAAIPVEQVSGMGL
                     DMNFGIYYTHKRFYAGFGMTHITQPELQLDENAYTYIGRSLNLMGGYNIQLKNPLIEL
                     QPSVFLLTDMQSFHADITARLEYNKMFNGGFSYRVNESVGIMFGVKLGRFHAGYAFDF
                     PTTALGRASSGSHELCVKYALKLNKTKTGKNRHKSVRIL"
     gene            complement(8492..8713)
                     /locus_tag="ACZPB4_12020"
     CDS             complement(8492..8713)
                     /locus_tag="ACZPB4_12020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004332134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2795 domain-containing protein"
                     /protein_id="HIR1098971.1"
                     /translation="MYWTLELASKLEDAPWPATKDELIDYAQRSGAPLEVIENLQEME
                     DEGEIYECMEDIWPDYPSKEDFFFNEEEY"
     gene            complement(8785..9348)
                     /locus_tag="ACZPB4_12025"
     CDS             complement(8785..9348)
                     /locus_tag="ACZPB4_12025"
                     /EC_number="2.5.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008817 - corrinoid adenosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cob(I)yrinic acid a,c-diamide
                     adenosyltransferase"
                     /protein_id="HIR1098972.1"
                     /translation="MKKSIIYTRTGDKGTTSLVGGQRVSKAHDRIESYGTVDELNSFI
                     GLLITALNDEKDTDFLSFIQHKLFTIGSYLATDQATTELKIESKVTPESIERIEREID
                     RLDNELPKMHAFILPGGCRSAALAHVCRTVCRRAERQIYRLAENCPVEEPVLIFMNRL
                     SDYFFVLARKECINNNGKEIIWDYTCV"
     gene            complement(9368..10159)
                     /locus_tag="ACZPB4_12030"
     CDS             complement(9368..10159)
                     /locus_tag="ACZPB4_12030"
                     /EC_number="2.1.-.-"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008171 - O-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HIR1098973.1"
                     /translation="MQILPKVNTLRKGSLLYRGIRYRKGFGVHSPFVFNLITKVIEEK
                     CSYYSFYDIELLRKQLLFREGEITYPDRQNKGKRKTRSIGEIVKRESIRPKHGALLFR
                     LTNYFKSKNILQIGTTMGLSTLYLTSYATGLRCIALENVPEFATIARQAFAKEGRNPI
                     DLRIGNYKDLLPQALNDINSLDFVFFNTLYEQHNNLWLFNECMRYAHNDTVFVFEGIK
                     ASRKMRELWEEICACPEVTVTLDLYSLGIVLFNKKLHKRDYIVYF"
     gene            complement(10295..11638)
                     /locus_tag="ACZPB4_12035"
     CDS             complement(10295..11638)
                     /locus_tag="ACZPB4_12035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HIR1098974.1"
                     /translation="MNKYLYTLLLAFSSLFMAEAQQLFDLKRCIETGLEQNYSIRIIR
                     NEQQISDNNATPGNAGYLPTVDMSGGFSGNINNNRNSLQDGSIEKANGINSETGNVGL
                     NVNWTVFDGFGIQAEYSRLKELQRMGELNTRMTIEDFVANLSSEYYNLIRQKIRLRNL
                     RSTLDLSKERLRIVEERYYIGSMSRLDLQQAQVDFNSDSSKVLNQLEVVHTSRIRLNE
                     LMALNNVEEEIQIKDSLIYPNPFLDEVDLWKNTLEANASLLIAQKNQTLSELDYKKVK
                     SRYYPYVKLNAGYGYTANWTEVGNYDLQQRLGLNYGVTIGMSLFDGFNRKREQRNARI
                     QIENQQLRIQELELALRADMSNFWMAYKNNLDLWSLEKENLVAAQENYRIAIDRYKLG
                     ELSGIELREAQNSLLEAEERLSVAEYSTKICEISLLQLSGQILTYIRPEPEKASF"
     gene            complement(11650..14685)
                     /locus_tag="ACZPB4_12040"
     CDS             complement(11650..14685)
                     /locus_tag="ACZPB4_12040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0042908 - xenobiotic transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HIR1098975.1"
                     /translation="MANISETSINRPVLSTVMMLVILLFGFIGYRFLGVREFPSVDQP
                     IISVNVSYPGANADVIMNQITEPLEQNINGIPGIRSLSSVSSQGSSRITVEFELSVDM
                     ETAANDVRDKVSRAQRYLPRDCDPPTVSKADADASPIMQIAIRSNKRSLMELSEIAEL
                     TVKERLQTIENVSGVDIWGQKRYSMRLWLDPIKMAGYGVTPMDVKNAVDNENVELPSG
                     SIEGNTISLSIRTLGLMHTAKEFNDLIIKEDNNNIVRFSDVGRAEVAPEDLRSLLKKN
                     GEPMVMTVIIPQPGANHIEIADEAYKRIEQLQKDLPEDVTIEMMYDNTRFIRASIGEV
                     QQTIYEAFLLVVLIIFLFLRDWRVTLVPVVVIPVSLVGAFFVMYISGFSVNVLTMLAV
                     VLSVGLVVDDAIVVAENIYVRIEQGMSPKEAGIEGSKEIFFAVVSTTITLISVFLPIV
                     FMEGMTGRLFKEFSIVIAGSVAISSFVALTFTPMLATKLLKRREKKNWFYRKTEPFFE
                     GLNTIYAKSLNAFLNHKIWSIPIVILLFGSIGYFWKNIRSELSPLEDRSMISVNMRGP
                     EGATFEFIRDYADRIEQIADSIAPEKQSIMTRSWEGGGSLNLILSDIKERERSQMEIA
                     ETLSKEVRKETLARAFVQQQSTFGGRRGGMPIQYVLQAPTLDKLQEFLPTFMQKVNES
                     PVFQMADVNLRFTKPEARIEIDRDKASLLGVSTRNIAQTLQYALSGQRMGYFYMNGKQ
                     YQILGEINRQQRNTPVDLKSIYVRSNNGEMIQLDNLVKVTENVAPPQLYRYNRFVSAT
                     VSSGLNKGYTIGDGLDEMDRIASEVLDGSFRTALSGESKEFRESSSSLMFAMILALLM
                     IYLVLAAQFESFKDPLVVMFTVPLAIAGALMFMSYSGITMNIFSQIGIIMLIGLVAKN
                     GILIVEFANQRQESGLSLPEAIRSSATQRLRPILMTSVSTILGLVPLVYATGEGAQGR
                     IAMGVAVVGGMLVSTFLTLFIVPAMYSFISTNRKKNITE"
     gene            complement(14697..15797)
                     /locus_tag="ACZPB4_12045"
     CDS             complement(14697..15797)
                     /locus_tag="ACZPB4_12045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HIR1098976.1"
                     /translation="MTKRAKWGVTAAILLMIAGMIAYPQLKNKFKASQDAASVVPTSG
                     TSLRNQTLNINAEVLKYQSLTDKIMSTGSTLPDEEVDLAFESSGKVVAIYFTEGSHVK
                     AGDLLAKINDKPLQAQLKKLEAQVPLAKDRVYRQRTLLEKDAVSQEAYEQVATEYEKL
                     MADIELVKANIAQTELRAPFDGIIGLRSVSEGAYVTSSSSVIAKLTKISPLKIEFSIP
                     ESYAAEVQDGTPILFRMEKNGMMQNYKATVYAVESKVDMATRTLKVRATYPNPGENIL
                     PGRYTSVEISKREIKDALAIPSEAVIPEMGKDIVYLYKNGVAEPQEITIGIRTESRVQ
                     VLQGLNVGDTLITSGVMQLRTGMKVSIDNLTE"
     gene            complement(16120..18780)
                     /locus_tag="ACZPB4_12050"
     CDS             complement(16120..18780)
                     /locus_tag="ACZPB4_12050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017141696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HIR1098977.1"
                     /translation="MNKKHLFTLLFTLLVWTSCNNQQHFITDAAYRAEVENDFQAKQA
                     ALPNGDLFAVFNDQMTPEEREALTFMYAYMPIGDITDYSGDFYLKNIRSSFQARNEMP
                     WGDSIPEDIFRHFVLPVRINNENLDESRMVFFDELKDRVKGLSLYDAVLEVNHWCHEK
                     VIYTPSDGRTSSPLASVKTAYGRCGEESTFTVAALRSVGIPARQVYTPRWAHTDDNHA
                     WVEAWVNGKWYFLGACEPEPVLNLGWFNGPAYRGMLMHTKVFGKYNGPEDVMERTDGY
                     TEINVIDNYAPSAKAVITVTDANGKPVKDALVEFKIYNYAEFNSVARKKTDADGKCSL
                     SAGKGDMLVWASKDGKFGYSKVSFGKDGEVTIALNKKPGDVETIALDIIPPVDGSIPA
                     EVTPEQKEANAKRLLEEDAIRNKYVATFYTEEKAEALAKELGIDPMKTEDFMIGSRGN
                     WMEIEKFLRETPAEKRVQAMALLDVVSAKDLRDTPASVFADHLNNTPAVQSEWFNEYI
                     MNPRVANEFLTPYKSFFAANIEPSLAKQAVENPQALVDWVKNNVSINDALNAQRIPIM
                     PMGVWKSRIADKGSRNIFFVAVARSLGIPARIEPVARKIQYFKDNAWVDVDFEAAVQT
                     TAKQGKVIASYQPIKALQDPKYYSHFTIAKVLPNGTLQTLNFERGGNVDMGLGDTWSG
                     LLKKPLSMDEGNYMLVTGTRMANGSVLAEIEFFNVEADKTTPIQLEMRESKDEIQVIG
                     NFNSENKFKRADNGEETSLLATTGRGYYIVALLGSRQEPTNHAMRDIAAVKKELEDWG
                     RGIVLLFPDEKGYKNFDPKEFGDLPGTITYGLDIDGAIQKEMATAMKLQNANTLPIFL
                     IADTFNRVVFVSQGYTIGLGEQLMKVIHKL"
     gene            19001..20500
                     /locus_tag="ACZPB4_12055"
     CDS             19001..20500
                     /locus_tag="ACZPB4_12055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="potassium/proton antiporter"
                     /protein_id="HIR1098978.1"
                     /translation="MFQNPEQVLLIASVILFLSIFAGKAGYRFGLPALLLFLGVGMLF
                     GSDGLGIQFSDPNVAQFIGMLALSIILFSGGMDTKVAEVKPIASQGVVLATLGVLATT
                     FITGGFIYWLFGLFGKYVTLTFPESLLLAAVMSSTDSASVFSILRSKGVYLKERLRPT
                     LELESGSNDPMAYMLTLLLIAYIQSGGMNIWEAGLSLVIQLSVGAIAGFLLGRLAVLI
                     INKIDIDNESLYPILLLATAFFTFAATTLCKGNGYLAVYIAGLVVGNAKIVHKKSMGT
                     FFDGFAWLWQIVMFLTLGLLVNPHELLPVTGVGVMVGVFMILIARPISVFLCLIPYKN
                     FSFKGKLYISWVGLRGAVPIIFATYPMIAGIEHAGMFFNIVFFITILSLLIQGTTVTQ
                     AAKWLDMVDEPERKDEFGIELPEEIKSAMSEIDITPAVLSHGNKLMQLTLPDHTLAVM
                     VKREGRYFIPKGNTELKENDKLLMISDNDEALLQAYDSLGVKDYTMKKN"
BASE COUNT         4916 a         5051 c         4869 g         5896 t
ORIGIN      
        1 gctagggcgt acgacaatgc ggtatatgtg gtattctcca atccgatcgg gcgtgattat
       61 aatgagatca agaacggttg ctcgatgatt ctggatcctt ttggcgatat cgtggcggaa
      121 tgccgtaaac tgggtgatga tttcgtgatc gctacagcta tccctgagaa attgagacag
      181 gctggaggat atcgttaccg aaatgcccgt cgtccggaac tttatgcgga tattatcggc
      241 caaccgcatg agtccaatca aaaggtagca tggttaacag aaacaacaaa tagcaaataa
      301 atagtatgca acaaacaaca atctctaagt cacctcgtgt agaggtggtg gatgcgctac
      361 gtggtttcgc tgtcttggca atcttattag tgcataatgt ggaacatttt atctatccgg
      421 tctatccgga cccggctacg ctgccgggat ggttgaacgt attgaatgaa ggcgtgttta
      481 cggtggtatt cgctttgttt gccgggaaat cgtattctat ctttgccttg ttatttggtt
      541 ttacctttta tatacagtat tcgaaccagc aggcgaaggg aaaagacttc ggttaccgct
      601 tcctttggag attactgctg ttgacgatct tcgctacgtt gaacgccgct ttttatccgg
      661 caggcgatgt tttgctgctg tatgcgatcg tgggcgttgt tttgtttatc gtgcgtaaat
      721 ggagcgataa ggctgtcttg ataacggcta ttatcttttt attgcagccg gtggagtggt
      781 atcattatat cgctagcctg tttaatccgg attaccaatt acccaattta ggagtagggg
      841 agatgtactc agagatggcg gagcatacca agcgggggga tttatggaat ttcatctggc
      901 agaacgtgac gttaggacaa aaggctagtt tgctctgggc tgttggtgcc ggccggtatg
      961 tacagacctg cgggttattt atgctgggaa tgttgatcgg gcgcaaaaag ttatttatcc
     1021 cctcggagga gaattcccgt ttttggataa agaccttgat cattactgcg atcgctttcg
     1081 gtcctttata ccaactgaaa gtattgttga tggatacggc ggacagcgct accgtgcgcc
     1141 agacggcagg tgttgtgttt gatatgtggc agaaattcgc ttttacgttc gtattggtgg
     1201 cttcctttgt gttactgtat cagcgcgagg cctttaagcg ttttacctct atcttacgct
     1261 cttatggaaa gatgagcttg acgaattatg tgacacaatc ttttgctggt gcgttgatct
     1321 atttcccgat cggcttgaat ctggctcctt actgcggtta tacggtcagc atgttcatcg
     1381 gtatcgcctt tttcttcttg caagtacgct tctgtaagtg gtgggctgaa agacataaac
     1441 acggaccgtt ggaaggtctt tggcataagt ggacatgggt aggttctaaa taaggatctg
     1501 attatctggt gaaatgagat ggggtatgtc ccgtctcatt tcattacaga cagttctcac
     1561 tccataaaag gtttggcata tttaatcatt ccatgcacgt tcttgagtcc ttccggtgcc
     1621 aactcgacaa ccatgcaata ttcgctgggg acatcgaatg gaaactcaat gccgaaatca
     1681 atcgcccttt tatatccgaa tctcggataa taatccttat gtcctaataa gacggccgat
     1741 ttatagccta gctctcccgc tcgcttatgc gcttcacgga tcaaagcgct accaacgcca
     1801 atcctttggt acttcggtac caccgaaacc ggtgctagcc caagagagat cacgctttgg
     1861 tcttctgata cgatttccac cttactcatc atgagatgcc ctatgatttc gccgtttaat
     1921 tcagcgacta aggagagctc cggaatataa gcgtccgttt ttcgtaaacg ttctacaagg
     1981 tacggttcgc tttgatcact gtcctccacg ttacggaaag caagttccac gacttccctt
     2041 actgcttgga aatcgttctc ttgctctggt ctaatcttga tttctttatt catatgttgc
     2101 gtatttccgg ttatcgctca gacccgtatc gtgagtccgt ttttatcttc tgcgtcgaac
     2161 actgcgtacc ggagcggatt tttctgcttt cggagccttg acagtgggag ctttcttttc
     2221 ggaggcaggc tctttggttg tagtaccttt tcctcttgcg gcgctctttc tggccttctt
     2281 cgcggctttg ctgtctaccg ctacttgagt cgtatccggt tgataccaga gtgatttctc
     2341 aaagccggtt aattgacctt cgatacgagc ttgctcgttc tttaaggaat ccggtgtcgg
     2401 gcaatacgcc tgcaatggca gattcatcaa gttttgggtc ttgatgatat ccccctcgaa
     2461 catccggcga cggaaatagt catccatcgt aaaagtcatg gcgttattca tattagacgt
     2521 catgatgtat gaattgctga tatacggacg tatattctcg taaggaagcc agaacatagg
     2581 catggttgtc tctcccatat cacctgtaga ggtaaggatc gggcaaatcg ccaatatctt
     2641 gacatcaaaa gcggaattat tctggtcgaa ataccatgct tcttttacat agtaagaccg
     2701 tacgtcggct gcaggtatat cgctttcatt gattacgaaa gtcggttcct cacccgctct
     2761 ccccggtatc tcctcataaa ggatgtagaa gcgatccagc aaatccttga agttgatcaa
     2821 atgggcttcg tcaaactcct cgtatccgtc cagatactca taggccttga tcttattctc
     2881 acctaaaagc tggaagatta cggagaaaag attcatctgt ccgttcatcg ggcgggtcgg
     2941 gtaataaagc ggagcgttct gctctttcat caagtccacc tgccggtaga taatacgcat
     3001 ccagcgagcg ttcccgatct cttgcgtcaa acgctcgttc atatcttggg cccgtacggt
     3061 cagttcgggt aaaccggtat ctttcttatc gtttctttcc ccacggctgg cttgaggcga
     3121 acggcgacgc gtttgttgtt gctgcgtagc atcgttctct gcttcttctt gtgcgtgaag
     3181 aggcatcgct gttaaaaaag tggcggccaa agcggctatg taatacagat gtttcatact
     3241 gcgaatctta atttacgatt acttcgatag tcggtatggt acgttcgata ccgtccggac
     3301 ctttcgcgac tacacgggtg atataaaaac gtttaccctt acttaaattg cggatatagt
     3361 ttttctgacg ttgcgagaag ttggttcctt cggccacttc cgggatagcg ttacccatgg
     3421 agtcgaagaa agtcagctca aaacgtaata ccgtatattt tacatttagc aaatcatcgt
     3481 cgatagcggc cagaataccg tcagcctcta ccaagctacg tttggcgatc atacctccct
     3541 tgaacttacg gacgttaccg ttttgatcct tatactcgat ataaggtagg ggatcgggga
     3601 gggcacgcac gcggaaggta gtctttgcca tctctatgtt ccggccatcc gccatacgag
     3661 cgtttaccgt gatcacggct tccgttccta ctttagacgg gcgggcttcc caaccatcct
     3721 tgctgcgggt taatgtgccg ttcgtcatgg tagctgtcac attaccgctc ggtacacccg
     3781 ggacggcgat acgcatcggg ttggcgatac cggcatataa tacgttcatc aatgtcgggg
     3841 ccacggtagc tgtcggctcg gtcacgaaat actcgctctc gaaatcccgg cgcatgatgc
     3901 tgccgtcgct attcggcatc tcgatataac ctttgatcgg gaatgtcccg gcagctccgg
     3961 tattcaccgt gaagactcct ttattctcgt aaggtaattc ttttccgttt acatagatcg
     4021 taggacgttt cgtagagtct accgccgata atacgatatt cgccttgtac tggcttcctc
     4081 gcattacgat ctggctttcc gggattacct gcgccgtgat ctggttcaca cggtaatcgc
     4141 caacgtctac gctattcaat aagttcgata agacctcacc ttcggcgtag cgaacgtcac
     4201 tttgcatttt tgttaacagg gtaacagccg ccgctaccgg catattctcg aacaaggcct
     4261 cttcccaagt acgggtattg atccccgctt tatgaggggg agtcgtgctt aggttcgcct
     4321 ccaatacggc agtcttcgcc gaatcttcga taaagccgcc catccagata cgatacttat
     4381 caatttccgc tctcagcttt ttaccttctc cgcttacagg agagagcatt acacgggaag
     4441 cggcttccaa atcatcctta tgctcgatgc tgtttacgtt ggcattctcg ccatcagcta
     4501 ccttagcgat acggatcttt aaatcttgta tatacgtata gaggctatct gaggctcttt
     4561 tcacctcacg ggccttcaat gcccactcac ccactttctg gggattctct tggtaataag
     4621 cttccatctc gtccgctacg atcttgtttc ggcgagagga gttatcgata gaggttcgca
     4681 agctaccttc caccaactca aaaccatcca gcacctccga cgacacattc agtgccatca
     4741 tggcgatgaa caccagatac atcaggttga tcatccgctg acggggagaa ttgggattat
     4801 ttgatattcc tgccatattt ctttacttca ttgggttgtt tgtatacgga gcctgttgtg
     4861 gctgttggta accatagggt tgctgatatt gctgttggta accgggctgt tgtggctgct
     4921 gatacatcgg ttgttgaggt tgttgttgcg gctgcgccgg ttgttggtag cccatattca
     4981 cggtcatcgc ttgcaataaa cgactgtata cttggttcaa ttcggccagt tggcgagtca
     5041 tcttttccgt ctcgttacgg aatacggaac tatctaccac cgatccgtca tacatctcac
     5101 ggatacgatt caagccacta ttgatgtgtt cgatagattc gatctgcgaa ctgatactct
     5161 tcaactggat ctcatagatg gtattcaatc cggatacgtt acggttcaat tgttccatct
     5221 ggtgtacgta accacgggag ttttggttga tgccatcgga attatccgtg atactcttat
     5281 aagagttcaa cagtgtatcg gatacgttcg taagcgaatt agtcacttgg ctgaaacgct
     5341 ccatgttctc agacatgcca gataattgct ccagatattt ttgggtagct tccgtcaatt
     5401 ccgccatctt ggaaatttgc tcggccgctc cgcttaattt cttgatgctc tcggataagt
     5461 tcttggtatc ttcttccgtc acgtccagat tacctgcgat attcaaggaa ccacctcttt
     5521 gcgcgttcgc cttagacgct gccgaaccga tatttattcc cccggctatc tcatcgtctt
     5581 ctacattatc cgtagaattg atcatggttg agatcggcgt accggtgaaa tccggacgat
     5641 ccatcgggtt ctttgatttc aatacgggga aaacatcttc ccaatgatac tccttgttcg
     5701 gatgctcgaa cgccgagata aagaatacga tagactcggt gatcatcgcc acgaacagga
     5761 tttggttagc gtatggtata tgtaataact taaataacgc accgaggatt acgatggacg
     5821 caccccaact atacaggaag ttcaatactc gttttcctct ttcgctggag aggaacatct
     5881 ccagtctgtt tttatatctt ctatattttc ccatcgtcgt attattgtct taaatgattc
     5941 aaaactttaa atttataatt cccgcttatt tctttccctt ggagcgagag aatcctattt
     6001 gggtacgtgc gcaacggaaa ccgatgtaag aacggctctc gttctggaac tcgaaagtac
     6061 gcatgtccga acggataaat tgtgagacat ctttccaaga acctcctcgc actactttct
     6121 ttttcatggc gtagggatcg ttcttggcgg cgttgtaacg cagatccggg ttcatgtcgc
     6181 tcatttggct cgggccagac tcggagtaag acgttgaggt ccattccgcc acgtttcctg
     6241 ccatatcgta taacccgaac tcattcgggg cgaaagagcc tacacgagac gtaatcaaat
     6301 ggccatcctc cgtataatta cctttacccg gcttgaagtt acccaagaaa caacctttgc
     6361 tgtcttgaag ctcgtcggta gaccaaggga acttattctc gttcttacct gtacgggcgg
     6421 catattccca ttctccttcg gacggaagac ggaatggctc taccaattgt cccggaggca
     6481 agctcaagga ttctttgtat aaattcgtac gccatacgca gaaggcagtc gcttgttccc
     6541 aagaaacacc gactacagga taatcatcgt aacccggatg agagaaatac atacgggtat
     6601 atggctcgtt gtacgcattc ttgaaatcgt tcacccagca attctcgtcc gggtagatat
     6661 tgacgatacg ggtattcaag aaatcccatt cgctgcttaa cgggcgggtg atcgtctcgt
     6721 tgattacacg tccttcatca tcgatgtaag cggtgtcctt ggagatcatg actacctcgt
     6781 tcggatctac ctgaatatcc gtattacgaa cccggtccgc cgggttcaat tgattcttgc
     6841 ggagggcggc ggcggtatag tcgtaccact cgtatttata gatcatttgt ttagggtcca
     6901 aacctttctc tccggtaacg ggattcgtgt aatagacact ttctatcgca cgttgctcat
     6961 cctcgttcgc ccgtctccaa ggaatcggac ggttccagtc caaatgcgga gtgacaggct
     7021 ccccgtaacg gtcttccgta atcttgaaca gatcgttgcc tccataagct gggtccgcca
     7081 agcgttcacg gataatagag tctctcacat aataaacgaa ctggcgatat ttggcgttcg
     7141 ttacctctgt ctgatccatc cagaacgcgt cgaaagagac ccctttcgtc tccggcatga
     7201 ttccccacaa ggaatccttg tcggcgggac ccatctcgaa cgaacctctt ttaaccaaga
     7261 ccattccata cggcgctggt tcattgaacg ctaccgatct gacacctgtc acctcaccgc
     7321 cggcactccg gagagattta ccgcaggagg taagcaaggc taccgttaca agtactaata
     7381 atactttttt catatactat aatatacgta cacttttatg tctatttttc cctgtcttcg
     7441 tcttgttcag ctttaaggca tacttgacac atagctcgtg gctaccgcta cttgcccggc
     7501 ctagggccgt ggtcgggaaa tcaaaggcgt aacccgcatg gaaacgacct agctttacgc
     7561 cgaacatgat gcccaccgat tcattcaccc gataggaaaa acctccatta aacatcttat
     7621 tatattccag cctagcggta atatccgcat gaaaactttg catgtctgtc agcaagaaca
     7681 ccgagggctg taattctatc aacggattct ttaattgaat attgtatcca cccattaaat
     7741 taagtgaacg acctatatag gtataggcgt tctcgtccag ttgaagctcc ggttgggtga
     7801 tatgcgtcat gccaaacccg gcgtaaaacc gtttatgggt atagtaaata ccgaagttca
     7861 tatccaaccc catgccgctg acctgctcta cggggatggc tgcgtcggtc tcttgatggt
     7921 actcggactc aacctttatc accttggttc cgtcgaacga ctggttgact aagccgattt
     7981 gcagacctcc gctcaagact cccccgaata atttatactt ataggcgtat tgcgccccta
     8041 catgtgtatt ctggaaaagt ccgatcgcct cggtaaatac aaccaatccg acaccatgat
     8101 tcgtcttgcc taaagtgagt ggcatatccg cggtaatgaa gaacgacttg ggtgccccat
     8161 gtacgccgat catttccaag cgggcgagag ccaatatatt caagtcctcc gtagctccgg
     8221 ccacggccgg gttataatac ggtttcgcca tgaagtattg acttaagcgt gcgtcatatt
     8281 gcgcccgtac gattcccgca caagtacaca aaaggatcag gatcgaaaga agacgtcttc
     8341 tcatttaaac attcacttca cgttgtaact acaaacgcag caaatccgga taaattgtat
     8401 tttcacaaaa aaacaacgag gcaggggagc tcgatcgtcc gccacctcgt tcttctattt
     8461 cttaattttc aatttccaat tctcaattga actagtattc ttcctcgttg aagaagaagt
     8521 cttctttact tggataatcc ggccagatgt cttccatgca ttcgtaaatc tcgccttcat
     8581 cttccatttc ctgcaaattc tcaatcactt ctaatggcgc accagaacgt tgtgcatagt
     8641 caataagttc atccttagtc gcaggccagg gtgcgtcttc caattttgaa gctaactcta
     8701 atgtccaata catagctgtc aagtattaat aaccgccgaa gcgatttggt tctctatttt
     8761 tccgcgaaaa tatgacttta tttattatac gcaagtataa tcccaaataa tttctttacc
     8821 gttattattt atgcattctt ttcgtgccag aacgaagaaa taatccgata aacggttcat
     8881 aaatatcaat acaggctcct caacggggca attctcggcc aagcgataga tttgtcgctc
     8941 ggcacgacgg caaacggtgc ggcaaacgtg tgcgagggcg gccgagcggc atcctcccgg
     9001 taggatgaac gcatgcattt tcggcagctc gttatccaga cggtctatct cccgctcgat
     9061 acgctcgatg ctctcgggcg ttaccttgct ctcgattttc aattccgtgg tcgcttgatc
     9121 cgtggctagg taagaaccga tcgtgaatag cttatgctgg atgaatgata agaaatcagt
     9181 atctttctca tcattcaagg ccgtgattaa taatccgata aaggagttca gctcatctac
     9241 ggtgccatag ctctcgatcc gatcgtgcgc tttcgacacg cgttgtccac ctaccagtga
     9301 agtggttcct ttatcgcctg ttctggtata gataatactc ttcttcatat ctgacttgtt
     9361 ttgaatccta aaaataaaca atataatctc gtttgtgcaa tttcttgttg aacaagacaa
     9421 tccctagcga gtaaagatct aaggtgaccg tcacttccgg acatgcgcag atctcttccc
     9481 aaagttcacg catcttacgg ctcgccttga ttccctcaaa aacgaatacc gtgtcgttgt
     9541 gcgcatatct catacattca ttaaacagcc agaggttgtt atgttgttca tataaagtgt
     9601 tgaaaaaaac aaaatctaag ctatttatgt catttaaggc ttggggaagc aagtccttat
     9661 aattaccgat acgcaaatcg atgggattac gtccctcttt agcgaatgct tgacgggcga
     9721 tcgtggcgaa ttccggtaca ttttccaagg cgatacatct caatcccgtg gcataggagg
     9781 ttagatataa ggtagacaac cccatcgtgg ttcctatctg gaggatattc ttggacttga
     9841 aatagtttgt caaacggaat aataaggcgc catgcttggg ccggatggat tcccgtttta
     9901 cgatctcgcc gatggaacgg gtctttcgtt tccccttgtt ctgccggtcc ggataggtga
     9961 tctctccttc ccggaataat aactgcttac gtaaaagctc tatatcatag aaactataat
    10021 aggaacattt ttcctcgatg accttcgtga tgaggttaaa aacgaaaggc gaatgtactc
    10081 cgaatccttt acggtagcgg atgccgcggt acaagagcga tccttttcgt aatgtattaa
    10141 cctttggtag tatttgcatt tccttttgtc gttaggcaat gatgaccttg ccatttgccg
    10201 cgaacttaca taaaaaaacg caattagcat aagcctctag tctttaaacg gagttataat
    10261 aacttgtgcc ataggcgtgg cactggcctt tatcctagaa actggctttc tccggctcgg
    10321 gacggatata ggttaatatc tgtccgctta actgaagcag cgagatctca cagatcttgg
    10381 tggaatattc cgccacggaa agacgctcct ccgcttccag tagactgttt tgcgcctcac
    10441 gcaattcgat accagacaac tcgccgagtt tatagcggtc gatggcgatc cggtagttct
    10501 cttgggcggc tacgaggttc tctttctcta ggctccatag gtcgaggttg tttttatagg
    10561 ccatccagaa gttgctcatg tccgcacgca gggcaagttc cagttcttgg atgcgcaatt
    10621 gctggttctc gatttggatg cgggcgttgc gttgctcacg tttccggttg aaaccgtcga
    10681 agaggctcat accgatggtc acgccgtaat taagccccag ccgttgttgg aggtcgtaat
    10741 tgcccacttc cgtccagttt gccgtgtagc cgtagcctgc gtttagcttg acatagggat
    10801 aatagcggct ttttaccttt ttataatcaa gctcagacaa cgtctggttc ttttgggcga
    10861 tcaggagtga ggcgttggct tcgagggtat tcttccatag atctacctcg tcgaggaacg
    10921 ggttcgggta gatcaaggag tccttgatct ggatttcctc ctccacatta tttaatgcca
    10981 ttaactcgtt caggcggata cgggaggtat gcacgacctc caattggttt aataccttgg
    11041 agctatccga gttgaagtcc acttgagcct gttgcaagtc cagacgggac atggagccga
    11101 tataatacct ttcctccacg atccgtagac gctccttgga aaggtccaag gtggaacgga
    11161 ggttacgcaa acggattttc tgccggatca ggttgtagta ctcgctggaa aggttggcta
    11221 cgaaatcctc gatggtcatg cgggtgttca attctcccat tcgctgtaat tctttcaagc
    11281 gagagtattc ggcttggata ccgaaaccgt cgaaaaccgt ccagttaacg tttagtccga
    11341 cgttacccgt ctcgctgttt ataccattcg ccttctcgat cgatccgtct tgcaggctgt
    11401 tacggttgtt attgatattt ccgctgaatc cgccgctcat atctacggta ggcagataac
    11461 cggcgtttcc gggggtggcg ttattgtcgc tgatctgttg ctcgttacga atgatacgga
    11521 tggagtagtt ctgctctaat ccggtttcga tacaccgttt cagatcgaat agttgctgcg
    11581 cctccgccat aaagagggaa gagaaggcca atagtaatgt atataggtac ttattcatgt
    11641 gtttatttat tattcagtaa tgttcttttt tcggttggtg gatataaacg aatacatggc
    11701 cggtacgata aacagggtca agaaggtcga taccaacatt ccgcctacta ccgctacacc
    11761 catggcgata cgcccttggg caccctcgcc cgtagcgtat accaatggca ccaaaccgag
    11821 gatggtggat acgctagtca tcaagatcgg gcgcagacgc tgggtcgcgg acgagcggat
    11881 cgcttccggc aaactaagtc ccgactcttg ccgctgattg gcgaactcta cgatcaagat
    11941 accgttcttc gccaccaaac caatcaacat aatgataccg atctggctga atatattcat
    12001 cgtgataccc gaatagctca tgaacatcag cgcaccggcg atagccaaag gtacggtgaa
    12061 catcactacc aacggatcct tgaaactctc gaactgggcg gccaacacca aataaatcat
    12121 caacaaggcc aagatcatgg cgaacatcaa actggaagaa ctctcacgga actctttcga
    12181 ctcgccggaa agagcggtac ggaagctacc atccagcacc tccgaggcga tacggtccat
    12241 ctcgtccaga ccatcgccga tcgtatatcc cttattcaat ccactggaaa ccgtcgccga
    12301 tacgaaacgg ttatagcgat acaattgggg cggcgccaca ttttccgtaa ccttaaccaa
    12361 gttatccaac tggatcattt ccccattgtt actacgtaca tagatcgatt ttaaatcgac
    12421 aggggtattt cgttgctggc ggttgatctc gcccaatatc tggtattgct taccattcat
    12481 atagaagtag cccatacgct gtccgctcaa cgcatattgc aaggtctggg cgatgttgcg
    12541 ggtgctgacg cccaataagg aagccttatc ccggtcgatc tcgatacgtg cctccggctt
    12601 ggtgaagcgc aagttcacgt ccgccatctg gaagaccggg ctctcgttca ccttttgcat
    12661 aaacgtgggc aggaactctt gcagtttatc caaggtcggg gcctgcaata cgtattggat
    12721 aggcataccg ccccggcgtc cgccgaaggt ggattgctgt tgtacgaagg cgcgggccaa
    12781 ggtctctttg cggacttctt tcgacaaggt ctcggcgatc tccatttgcg agcgttcccg
    12841 ttccttgata tcgcttaata tgaggtttag cgaacctcct ccttcccacg agcgggtcat
    12901 gatggattgc ttctcgggag cgatggagtc ggctatttgc tcgatacggt ccgcgtagtc
    12961 gcggataaac tcgaaggtag ccccttccgg cccgcgcata ttcacggaga tcatggaacg
    13021 gtcctccaaa ggcgataact cggaacgaat gttcttccag aagtacccga tcgatccgaa
    13081 aagaaggata acgataggga tcgaccatat cttatggttc aagaatgcgt tcaacgactt
    13141 ggcgtagatc gtgttcaatc cctcgaagaa cggctcggtc ttccgataga accagttttt
    13201 cttctctctc ctcttcaata gcttggtagc caacatcggt gtaaacgtaa gggccacgaa
    13261 cgaggagata gcgaccgaac cggcgatcac gatactgaac tccttgaata agcgccccgt
    13321 cataccttcc ataaacacga tcggcaagaa tacggagatc agggtgatcg tggtagatac
    13381 cacggcgaag aagatctctt tcgatccttc gatacccgcc tctttcggtg acatgccttg
    13441 ctcgatacgt acatatatat tctccgccac cacgatcgcg tcgtctacca ccagaccgac
    13501 cgagagcacg accgccaaca tcgtcaatac gttgacggag aatccggaga tatacatcac
    13561 gaagaaagct cctaccaacg atacggggat aacgacgaca ggaaccagcg tgacccgcca
    13621 gtcgcggagg aacaagaaga taatcaatac gaccaagagg aaagcctcgt agatcgtctg
    13681 ttgtacctcg ccgatagagg cccggataaa gcgggtgttg tcatacatca tctcgatcgt
    13741 gacatcttcc ggcaggtctt tttgtaattg ctcgatacgc ttgtaggctt cgtcggcgat
    13801 ctcgatatgg ttggctcccg gttgggggat gataacggtc ataaccattg gctcgccgtt
    13861 cttcttcagt aagctccgca agtcctcggg agctacctcc gcacgtccga catcgctgaa
    13921 gcgtacgata ttgttgttgt cttccttgat gattaaatcg ttgaactcct tggcggtatg
    13981 catcaatcct aaggtacgta tggataagga gatcgtattt ccctcgatac taccggaagg
    14041 aagctccacg ttctcgttat cgacggcgtt tttcacgtcc atcggggtca ctccgtaacc
    14101 cgccatcttg attgggtcca gccatagacg catggaatac cgtttttgtc cccagatatc
    14161 cacgccactc acgttctcga tggtctgcaa acgctctttc accgttagct cggcgatctc
    14221 gctcaactcc atcaacgagc gtttgttgct tcggatggcg atctgcatga tcggggaggc
    14281 atcggcatcc gctttcgata ccgtaggcgg gtcgcagtcg cggggaaggt agcgttgggc
    14341 acgagatact ttatcacgta catcgttcgc cgccgtttcc atatccacgg acaactcaaa
    14401 ctctaccgtg atgcggctgc tgccttggct actcacgcta ctcaatgaac ggatacccgg
    14461 gataccgttg atattctgtt ctaacggctc ggtgatctgg ttcatgatca cgtcggcgtt
    14521 cgctccggga taagatacgt tgaccgagat aatcggctgg tctacgctcg ggaactcccg
    14581 gacgccaagg aaccggtaac cgataaagcc gaacaggagg atgaccagca tcatcactgt
    14641 cgagagtacg ggccggttta tactggtttc tgaaatattt gccatcgttc ttctccttat
    14701 tcagtcaagt tatcaataga aactttcatg ccggtacgta actgcatcac gccggacgtg
    14761 atcagcgtat cgcccacatt caacccttgc aatacctgta cacggctctc ggttcgtata
    14821 ccgatcgtga tctcttgagg ctcggccacg ccgttcttat ataagtaaac gatgtctttt
    14881 cccatctcgg ggataacggc ctcgctgggg atggctaaag cgtccttgat ctcccgcttg
    14941 ctgatctcga cggaggtata acggccgggt aagatattct cgcccggatt cgggtaagtg
    15001 gcacgtactt tcaaggtacg ggtcgccatg tcgaccttgc tttccacggc gtaaacggtc
    15061 gccttatagt tctgcatcat accgtttttc tccatgcgga acaggatcgg ggttccgtct
    15121 tgtacctcgg ccgcgtagct ctcgggaatg gagaactcga ttttcaacgg ggatatcttg
    15181 gtcaacttcg cgattacgga agaggaggaa gtaacgtacg cgccctcact cacggagcga
    15241 agtccgatga tcccgtcgaa aggagcccga agctctgtct gggcgatatt cgctttgact
    15301 agctcgatat ccgccattag cttctcatat tcggtggcta cttgctcgta ggcttcttgg
    15361 ctgacggcgt ctttctccag caaggtgcgt tggcgataga cacgatcctt ggctaaagga
    15421 acttgggctt ccagcttctt tagctgggct tgcagcggct tgtcattgat tttagccaac
    15481 agatcgcccg cctttacgtg gctaccttcc gtgaaataga tggctaccac cttaccggaa
    15541 gactcgaaag ccaaatccac ctcttcgtcc ggaagggtac ttccggtact catgatctta
    15601 tcggttaatg attggtattt caatacctcg gcgttgatgt taagtgtctg gtttcgcagg
    15661 ctcgtgcccg atgtgggtac gacggaagcg gcatcttggg atgccttgaa cttgtttttc
    15721 aattgagggt aagcgatcat tcccgctatc attaataaga tagccgccgt aactccccat
    15781 ttcgctctct ttgtcatcat gttctcgtat ggtatttact gataatttac actcgttact
    15841 ccaaaatata taactaaacg caagtttaga ctctcctttc gtaaaaaggt ttaatcaaag
    15901 atattatttt tttgagagat gaatccccga ttgggaagaa cgggaaaaat aagggaatta
    15961 aaacgaatct agggaggaag tctgatcggt ttgtggtaga agaaatgagt gtctcctgtc
    16021 gtatagatct tttcacctat gtgaaaagaa cgtttcacag ccgtgatccg atcgtttcac
    16081 atgggtgaaa agatcagatc acacttgtga aacgatctgt tatagcttat gtatgacttt
    16141 cattaactgc tcgcccaagc caattgtata gccttgagag acaaatacga cacgattgaa
    16201 cgtatcggcg atcaagaaga tcggcaaggt attggcgttt tgcaatttca tcgctgtagc
    16261 catctccttt tggatcgccc cgtcgatatc cagaccgtat gtgatcgtgc ccggtaaatc
    16321 gccgaactct ttcggatcga agttcttata gcctttctcg tccgggaaga gaagcacgat
    16381 gcctcgtccc caatcttcta gttccttctt cacggcggcg atatcacgca tcgcatggtt
    16441 tgtcggttct tggcgggagc ctagaagcgc tacgatatag tagccacgtc cggtagtagc
    16501 tagcaagcta gtttcctcgc cgttgtccgc acgtttgaat ttattttcgg agttgaaatt
    16561 accgatcacc tgtatctcgt ccttgctttc gcgcatctcc aattggatcg gggtggtctt
    16621 gtctgcctcc acattgaaaa actcgatctc ggccaatacg ctaccgtttg ccatacgagt
    16681 accggtcact aacatataat taccttcatc catggataac ggtttcttca gtaatccgct
    16741 ccaagtatct cccaagccca tatccacatt accgcctctc tcgaaattca aggtctgtaa
    16801 agtaccgttc ggcaaaacct tggcgatcgt gaagtgactg taatatttcg ggtcttgcag
    16861 cgccttgatc ggttggtaag aagcgattac cttgccttgt ttagcggtcg tctgtacggc
    16921 agcctcgaaa tcgacgtcta cccaagcgtt gtctttgaag tactggatct tgcgggctac
    16981 cggctcgata cgtgccggaa tacctaagct acgagccacg gccacgaaga agatattacg
    17041 ggagccctta tcagcgatac gggatttcca tacacccatc ggcatgatcg gaatacgttg
    17101 tgcgtttagt gcgtcgttaa tggagacgtt attcttcacc caatccacca atgcctgtgg
    17161 attctctacg gcttgtttcg caagggaagg ctcaatgttt gcagcgaaga aactcttata
    17221 aggagtcagg aactcattgg ccacacgagg attcatgata tattcattga accattcgct
    17281 ttgaacggcc ggcgtattgt ttaaatggtc cgcaaagaca gacgcaggtg tatcacgtag
    17341 atccttagcg gatacgacat ccaataaagc catcgcttgc acacgcttct cggcgggagt
    17401 ctcccgtaag aacttctcga tctccatcca gttaccacgg ctaccgatca tgaaatcctc
    17461 tgtcttcatc ggatcgatac ccaattcttt cgctaaagcc tccgctttct cttccgtata
    17521 gaaagtagct acatatttat tacggatagc gtcttcttcc aataaacgtt tggcgttcgc
    17581 ctccttttgc tccggtgtaa cttccgctgg gatagagccg tccaccggtg gtatgatatc
    17641 tagggcgatc gtctccacat ctcccggttt tttgttcaag gcgatcgtaa cctctccgtc
    17701 tttgccgaaa gagaccttgc tgtagccgaa cttgccgtcc ttactggccc ataccaacat
    17761 atcccctttt ccggcggata atgagcattt gccatccgcg tccgtcttct tgcgggctac
    17821 actgttaaac tcggcatagt tataaatctt gaattctacc aaagcgtcct ttaccggctt
    17881 gccattggca tccgtaaccg tgataacggc tttagccgaa ggcgcgtaat tatcgatcac
    17941 gttgatctcg gtatacccat cggtacgttc catgacatcc tccgggccat tgtatttacc
    18001 gaatactttc gtatgcatca acataccccg gtaagcaggg ccgttgaacc aacccagatt
    18061 caataccggt tcgggctcgc aagcgccgag gaaataccat ttaccattca cccaagcttc
    18121 tacccatgcg tggttatcat ccgtatgcgc ccagcgaggc gtatatacct gacgcgcggg
    18181 aatacccacg gaacgtaaag cggctaccgt gaaggtagac tcctcgccgc aacgaccgta
    18241 agcggtcttt acggatgcca aaggggaact tgtgcgccca tcggaaggag tatagataac
    18301 cttctcatga caccagtgat tcacttccag tacggcgtcg tacaacgaga gacccttcac
    18361 ccggtctttc aactcatcaa agaaaaccat gcggctttca tccagattct cattgttgat
    18421 tcgtaccggc aatacgaaat ggcggaagat atcctctggg atgctatcgc cccaaggcat
    18481 ctcattccgt gcttggaaag aggaacggat gtttttcaaa tagaaatcgc cactatagtc
    18541 cgtgatgtct ccaatcggca tataggcgta catgaaggtt aacgcctccc tctcttcggg
    18601 agtcatttga tcgttaaata ctgcgaaaag gtctccgtta ggcagggcgg cctgtttcgc
    18661 ttggaaatcg ttctcgacct cagctcggta agcggcgtcg gtaataaaat gttgttggtt
    18721 gttacagctc gtccatacga gtaatgtgaa caacagcgta aatagatgtt ttttgttcat
    18781 aaagcggata tgtatgtttg ccaaaagtaa tgattctatg cgagatagaa aaattctcga
    18841 acaatttgta agaaagattt gtttttctat agaaagaata aatctggtct tcctgtaaat
    18901 ttgggaccgg atttcttctt tttgtgtgat tataattaca aaaagtttac gaactttgtg
    18961 acaaagtatc aaatcactaa tcataaaacc cgttttgcgt atgtttcaaa atcctgagca
    19021 agtgctatta atagcttctg tgatcctgtt tttaagtata ttcgccggta aggccggtta
    19081 tcgtttcggc ttacccgctt tgttgttgtt ccttggtgtg ggaatgttgt ttggcagcga
    19141 tggtctgggc atccagttca gcgatccgaa tgtagcccag tttatcggca tgttggcgtt
    19201 gagtatcatc ttgttctcgg gtggtatgga cacgaaagtt gcggaggtca aacctatcgc
    19261 ctcgcaaggt gtggtattgg ctacgctcgg ggtgttggct acgaccttta tcacgggcgg
    19321 gtttatctat tggttatttg gtttatttgg caaatatgtt acgttgactt tcccggaatc
    19381 tttattgctg gcggcggtca tgtcctctac ggactcagcc tcggttttct ccatcttgcg
    19441 cagtaaaggg gtttatttga aagagcgtct gcgtcctacc ttggagctgg agagtggtag
    19501 taatgacccg atggcttata tgcttacctt gcttctgatc gcttacatac aaagcggagg
    19561 tatgaatatt tgggaggccg ggctatcctt ggtcattcaa ttatcggtgg gagctatcgc
    19621 cggtttctta ttggggagac tggctgtgtt gattatcaat aagatcgata tagataacga
    19681 gtctttgtat ccgatccttt tattggctac ggctttcttt accttcgccg ctacgacctt
    19741 atgtaagggt aatggctatt tagcggttta tatcgctggt ttggtggttg gtaacgctaa
    19801 gattgttcac aagaaaagta tggggacgtt ctttgacggt ttcgcttggt tgtggcagat
    19861 cgtgatgttc cttacgttag gcttgctagt gaacccacat gagttattac cggtgacggg
    19921 tgtaggtgtt atggtgggag tctttatgat cttgatcgcc cgtccgatta gcgtgttcct
    19981 ttgcttgata ccttataaga atttctcctt caaaggtaaa ctgtatatct catgggtggg
    20041 attacgcggg gcggttccta ttattttcgc tacttacccg atgatcgccg ggatcgagca
    20101 tgccggtatg ttctttaata tcgtattttt tatcacgatt ctttctttgc tgattcaagg
    20161 aaccacggtt acccaagccg ctaaatggct ggatatggtg gatgagccgg aacgaaagga
    20221 tgagtttggc atcgagcttc ccgaggagat caagagcgct atgagcgaga tcgatattac
    20281 cccggcggta ttatcccatg gaaataaatt gatgcagctg actttacccg atcatacctt
    20341 ggcggtaatg gtgaaacggg aaggccgcta tttcatcccg aaaggaaata cggaattaaa
    20401 ggagaacgac aagttgttaa tgatctccga taatgacgag gcgcttttgc aggcgtatga
    20461 ttccttgggg gtgaaggatt atacgatgaa gaagaattga aataatgtgc caatgtaggc
    20521 aatgtgccaa tgcgaatact atttgtgtaa aataagcatt ggcatattgg cacatatgaa
    20581 catattggca cattatttta tcgtaccggg aactcggtta tacgtaaagt ggtacagcca
    20641 taaggaatta actcgatcgt ctcttcatca cccatcggtt cgttggcttg catgaagaaa
    20701 tttacggggc cggcggaacc tttgaacatt tt
//
LOCUS       DBMDTB010000076        19912 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_903_length_19912_cov_11.583716, whole genome shotgun sequence.
ACCESSION   DBMDTB010000076 DBMDTB010000000
VERSION     DBMDTB010000076.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 19912)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 19912)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19912
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_903_length_19912_cov_11.583716"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            219..722
                     /locus_tag="ACZPB4_12060"
     CDS             219..722
                     /locus_tag="ACZPB4_12060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4494 domain-containing protein"
                     /protein_id="HIR1098979.1"
                     /translation="MHNWFECKVSYEKMLENGMQKKVTEPYLVDALSFTEAEARIIEE
                     IRPFITGEFTVTDIKRARLSELFFNENGDRFYKIKVYFITLDEKSGAEKKTAAQMLAQ
                     ATTLKEAIAVLEDGMKGTLADYTIASVTETQLMDVFPFDANSIPGEKKSGEELIAEQK
                     QQAEQRG"
     gene            727..1395
                     /locus_tag="ACZPB4_12065"
     CDS             727..1395
                     /locus_tag="ACZPB4_12065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HIR1098980.1"
                     /translation="MSIAQNIVQLKTSLPQGVTLVAVSKFHPVEALWEAYNAGQRVFG
                     ESRAQELSAKQKVLPEDIEWHFIGPLQSNKVKDIAPFIHLIHSIDSLKLLAEVNKQAK
                     KHDRTIRVLLEIHVAQEESKHGLSPEECKELLRDESSAEFQHIRICGLMGMATNTDDT
                     GLIREEFRNIHDLFIELKETLCKDNVDFKEISMGMSHDYPIAIQEGSSLIRVGTSIFG
                     EREY"
     gene            1425..2402
                     /locus_tag="ACZPB4_12070"
     CDS             1425..2402
                     /locus_tag="ACZPB4_12070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase-like protein"
                     /protein_id="HIR1098981.1"
                     /translation="MIDIKTQYAGLTLRNPIIVGSSGLTNKAERNRDFEKAGAGAIVL
                     KSLFEEQIEMQSEALMQDSDYPEAADYIRGYVKANQVNDYLELIKKSKELCTIPIIAS
                     INCYKADAWIDFARQIELAGADALELNVFFMETELTEDFESIRDTYVSIIRKVKETVS
                     IPVIMKIGKNYSNIPSLVNLLKVNGADGVVLFNRFYQPDIDINNMQIVSGNVFSNHSD
                     LSDTIRWTAIVSGKIPGISIASSTGVHDWEDVVKCLLAGASAVQMCSAVYTHGAEIIS
                     QVLTCVEEWMHQAHYQSLSQFQGKLNYANIPNPAMYERSQFMKYFSNRD"
     gene            2612..2977
                     /locus_tag="ACZPB4_12075"
     CDS             2612..2977
                     /locus_tag="ACZPB4_12075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HIR1098982.1"
                     /translation="MEPICAIKDIYKILYQFEKNFSEVHAITINEAMLLCCLKDNEAK
                     SAGMICDYIGLSNSRVSKVITSVENKGFIRRNINKEDKRQMFFSLTPKGKEKIQQMMQ
                     AELNMDSLFNQLKEYIQKG"
     gene            3045..5513
                     /locus_tag="ACZPB4_12080"
     CDS             3045..5513
                     /locus_tag="ACZPB4_12080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HIR1098983.1"
                     /translation="MKYLIIGGVAGGATVAARLRRMDEKAEIILFERGKYVSYANCGL
                     PYYIGDTINDRNKLFVQTVKGFTDRFRIDIRTEQEVTRILPESKQVEVKKLGTGETYT
                     ETYDKLVLSPGAEPLRPRIEGIESKKIFTLRNVPDTDTIKNYVNTEKPRTAVVVGGGF
                     IGLEMAENLHELGVHVTVVEMANQVMAPLDYSMAAIVHQQLIGKQVGLMLEDGVSRFE
                     ETSRGVTVHLKSGKQIPADMVLLSIGVRPETRLAKEAGLTIGALGGIAVNEYMQTSNP
                     DIYALGDAVEVRHLVTGKPALIPLAGPANKQGRIVADNIVSGNKETYDGTMGTSIAKV
                     FDLTVATAGANAKLLKREGIAYQSSYTHGASHAGYYPGAVPLSIKILFAPEDGRLLGA
                     QVVGFGGVDKRIEMLAQVIQRKGTVYDLTELEHAYAPPYSAAKDPVNMAGFVAENLLT
                     RKAKAIQWREIQNLSPDTVRIDVRTRDEYSLGTIPGFINIPVDELREHLAELPKDKLI
                     VVTCAVGLRGYLAYRILTQNGFTNVRNLSGGYKTWSVATAKIKNEPACAPCSSEAVSD
                     KASGKSSSCKSTPAATAIKVDACGLMCPGPIMQLKKNYENLREDESLEITATDQAFGK
                     DVSSWCKITGAELVSLENKGGTIAATVRKKKAECKIATGGNSADNKTLIVFSDDLDKA
                     LASFVIANGAASTGKKVTMFFTFWGLNVIKKREKPAVSKDIFGKMFGWMLPANSEKLK
                     LSKMNMGGAGSWMMRLIMKKKRIDSLESLMAQAVENGIEMIACTMSMDVMGVKKEELM
                     DNVVLGGVATYLERAEDANVNLFI"
     gene            complement(5583..5840)
                     /locus_tag="ACZPB4_12085"
     CDS             complement(5583..5840)
                     /locus_tag="ACZPB4_12085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2442 domain-containing protein"
                     /protein_id="HIR1098984.1"
                     /translation="MNTSVNVLMINAQGIMLSVLGRDYFLSYNRVPWLKEARISNVLN
                     VRMAGRNAIEWPELDVDLEIESLKHPERYPLIMKRSTLDFV"
     gene            complement(5856..7130)
                     /gene="serS"
                     /locus_tag="ACZPB4_12090"
     CDS             complement(5856..7130)
                     /gene="serS"
                     /locus_tag="ACZPB4_12090"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005641068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HIR1098985.1"
                     /translation="MLTIKLITENTDAVIRGLEKKHFKGAKESIDKVLELNDKRRIAQ
                     NQLDKNLAEVNATSKSIGQLMKEGKKEEAEAAKKHVSEIKEVSKALQVEMDQAAEELQ
                     NLLYTIPNVPYDEVPEGISAEDNVVEKMGGMETELPKNALPHWELAKKYDLIDFDLGV
                     KITGAGFPVYKGQGARLQRALINFFLDEARDAGYLEIMPPTVVNSASGYGTGQLPDKE
                     GQMYHCEVDDLYLIPTAEVPVTNIYRDVILDEKQLPIKNCAYTQCFRREAGSYGKDVR
                     GLNRLHEFSKVELVRIDKPEHSKQSHQEMLNHVEGLLQKLELPYRILRLCGGDMSFTA
                     ALCFDFEVYSEAQQRWLEVSSVSNFDTYQANRLKCRYRDENKKTQLCHTLNGSALALP
                     RIVAALLENNQTPEGIRIPKALIPYTGFDMIK"
     gene            complement(7178..7717)
                     /locus_tag="ACZPB4_12095"
     CDS             complement(7178..7717)
                     /locus_tag="ACZPB4_12095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NlpC/P60 family protein"
                     /protein_id="HIR1098986.1"
                     /translation="MKNSIPLGFIRIFILLICLTSCGSKKQQKVALPADFKGPKELAR
                     LYGVRITPEDNIFLYNEGARWLGVRHKLGGSTKRGVDCSGFVSIVYREVYGKQLARSS
                     ADMLKYNCKKVSRAKLQEGDLVFFKTGRGGKRGVPNHVGIYLKNGRFIHTSTSSGVMV
                     SSLSEPYYTRTWLTGGRVK"
     gene            complement(7847..8557)
                     /locus_tag="ACZPB4_12100"
     CDS             complement(7847..8557)
                     /locus_tag="ACZPB4_12100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HIR1098987.1"
                     /translation="MKTLTCMIVDDEPLAVKMLEDFVSRTPYLRLAASFNDPVLALST
                     LCESPVDVLFLDIQMPDLDGLNLSRMVPPSTRVIFTTAFKEYAFDSYEVNALDFLLKP
                     IRYHKFLGAVEKARQWFEMNSVKEERGSLFVRVDSQLRQVEISRILYVTGLKDYVMIY
                     LEGEARPLITHVTMKAMEEMLSTGRFMRVHRSYIVALDKIRSVDRNNCVYIGKEIIHV
                     TDAYKEAFNAYLKAAQPS"
     gene            complement(8554..9576)
                     /locus_tag="ACZPB4_12105"
     CDS             complement(8554..9576)
                     /locus_tag="ACZPB4_12105"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1098988.1"
                     /translation="MKLTRQDYILAGGQALLWITLWLIPPAIDFFIRFNPSSAFEVWK
                     INTGFITPLAIVFTANFYVLVPYLLYRDRKMLFGLMNLLLITGANLWIFSPKADFPDE
                     WRSGMYMVAFGAFFLHLLVIGCAVGFRYIVRWGDMQMRLKEERQKNAEAELAWLKNQL
                     NPHFLFNTLNNISSLVQIDQDTAQERIGQLSDLLRYTLYESNHELVPVEGEIEFMSNY
                     IELMRLRCNELATVEVDLRIPPKPMRIVPLLFISLIENAFKHGVNSRKSSFVRIRFKA
                     EGDDLVFTCENSDHPKPDVNRSGSGIGLENLRRRLDLAYPGRYRYDQALRENSYFVQI
                     TLRDCL"
     gene            complement(9676..11670)
                     /locus_tag="ACZPB4_12110"
     CDS             complement(9676..11670)
                     /locus_tag="ACZPB4_12110"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 97 protein"
                     /protein_id="HIR1098989.1"
                     /translation="MSKNILFAFLFLMGAIPSIAQKNYQVQSPNRDIKVEVTVADKVT
                     FAIVQDHSEVMNSAVSMTLQGGEVLGANPKVLKVTKTSVDKEIPSPFYKKDVVKDIYN
                     EMQISFRGNYGLVFRVYNDGVAYRFTTKRKEPIVIADEEAVYNFPSDYKTFTAYVNST
                     KPTFEEQFFNSFEQPYANETITGLNDKRLKILPLLVDLGDGRKICITEADLEDFPGMF
                     LNNETGKPSFKAVHAPYPKVKEQGGHNQLQMLVKERENYIAKTSGTRSFPWRAFIISR
                     NDKELADCDMVYRLASPSRVNDISWIKPGKVAWDWWNDWNLYGVDFRAGINNPTYKYY
                     IDFAAEHGIEYVILDEGWAVNLQADMMQVIPEIDLQELVDYGKSKNVGIILWAGYWAF
                     ARDMENVVKHYSDMGVKGFKVDFLDRDDQEMVNFVYKASEVCAKYKMLVDFHGVFKPT
                     GLQRTYPNVLNYEGVNGLEQMKWSSEKEFDMVTYDVTIPFIRMIAGPMDYTQGAMRNA
                     ARGNHRSVNSEPMSQGTRCRQLATYVIFESPFNMLCDAPSNYRREKECTEFISNIPTI
                     WDETVSLAGKVSEYVAIARRHGNDWYIGALTNWTPRELDLDLSFLGEGDYTLELFKDG
                     INADRAARDYKKEVIPVPTDRKLKIHMAPGGGYAARIQKR"
     gene            11753..13492
                     /locus_tag="ACZPB4_12115"
     CDS             11753..13492
                     /locus_tag="ACZPB4_12115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HIR1098990.1"
                     /translation="MMRLHKILLTLVCFTVLSAHAQWKWLNPLECGFPVIQNQGWTEE
                     IGDRYVRLPQRAEGKVRKPVWDLSRNSAGLAIHFFSNAPELKVRYQVSGPLNMPHMPT
                     TGVSGVDLYSIDSDGQWRFYFGGYPSGDTLQYHYTNIGKDLYHDRGYEFRLCLPPYNT
                     IKWLEIGVPENDELTFIPVSPEKPILLYGTSIAQGACASRPGMTWGTILQRSLGYPLI
                     NLGFSGNGRLEKEVLDFICEIDARLYILDCLPNLTPKSKDEITQLVSDAVKQIRATHS
                     SPILLVEHAGYSNALADDTKLQDYVRMNEGAKKAFEELQAQGIKDIYYLTREELGLHP
                     DAWVDYVHPSDWGMETQANAVERKVREILRIPKGDLSTTMPVTQRREPNNYEWQKRHR
                     DILSLNQSNPPRRVILGNSITHFWGGEPKGPSVRGMETWEKIMRPAGFHNLGYGFDRI
                     ENVLWRVYHGELDGYKAEEVVLMIGTNNIGINNDNEIVEGIRFLLSAIRQRQPEAKIK
                     VIGILPRRNQEERVRNLNLRIRQIAETGWYTFKNPGTKLLQEDGKINESLFSDGLHPN
                     EEGYKRIVDEIAH"
     gene            complement(13505..14041)
                     /locus_tag="ACZPB4_12120"
     CDS             complement(13505..14041)
                     /locus_tag="ACZPB4_12120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CinA family protein"
                     /protein_id="HIR1098991.1"
                     /translation="MKLLFSHNETPSIIITMEVDDLPIELEVADALKSGHLMMGTAES
                     CTGGKIASMITSMAGSSEYFTGGVVAYCNEVKHHVLGVSEADLNTFGAVSQPVVEQMA
                     RGTMRVLGCDCAVATSGIAGPGGGTPSKPVGTVWIAAAYKERILSECYHFGENPRMEN
                     IRLSAEAALRMLLRLIRE"
     gene            complement(14106..15125)
                     /gene="tsaD"
                     /locus_tag="ACZPB4_12125"
     CDS             complement(14106..15125)
                     /gene="tsaD"
                     /locus_tag="ACZPB4_12125"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HIR1098992.1"
                     /translation="MSITILGIESSCDDTSSSVIRDGVMLSNVIASQAVHEAYGGVVP
                     ELASRAHQQNIIPVVAEAIKRAGIDKSELSAVAFTRGPGLMGSLLVGTSFTKGLAASL
                     DIPMIEVNHLQAHVLAHFIKETPDDDHAPSFPFLCLLVSGGNSQIIKVNAYNDMEVIG
                     QTIDDAAGEAFDKCAKVMGLGYPGGPVVNRLANEGNPNAFTFSKPHIPGYDYSFSGLK
                     TSFLYTLRDHLKDDPDFIEKNKRDLCASLQATVIDILMSKLRKAAKDLHIKEVAVAGG
                     VSANSGLREAFLDHAKRYGWKVHIPKFSFTTDNAAMVAITGYYKYMDKEFCPMDAAPF
                     SRVVL"
     gene            15265..19728
                     /locus_tag="ACZPB4_12130"
     CDS             15265..19728
                     /locus_tag="ACZPB4_12130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translocation/assembly module TamB
                     domain-containing protein"
                     /protein_id="HIR1098993.1"
                     /translation="MPGILLRIPYIQNKVSEVATTQLSGHLGVPVKIGNVDIEWFNRL
                     VLEGLYLEDQDGKVMFEANHVAAGFEIMPLLEGKFVFTTVRLFGFSFNLRKHTPESPL
                     NLQFVIDAFASKDSIKKEKNIDLRFNSIMIRRGNFSYNVDSEKETPGKFNAKHIDIKN
                     LSAKISLKAFNKDSVNAHIKKMSFDEASGFSLNKLSLNVVGNRDSAFVQDFEVRLPQT
                     DLKIGRARIDLSEIDSLPALLNNAPIDLNITPSQICLKDLSPFVPAFKNFADTIELSA
                     EANGYINNFNLKRLTLKYSDKMLFIGQMELKNITHPEETYLLGKVNKMYITTDGISSL
                     ANNFNERPKSLPAPVVKLGTINFTGEISGFFDNLVAFGKLSSSIGSIQTDLIFGSNKD
                     KNIAAYLRGRIASSNLRLHELFGENNPFGEARFDINIDTRRPVGGNFSGNIQAQVKEF
                     DYKAYKYKDINLSGNFRKSSFDGTIHVDDPNGELHAQGIFQHQGQNSLFNFTARLDHF
                     RPDRLNLTDKYEAPNISLALNADFTGDNIDNLEGSITLDSLSFETTPSSFFLKKFEVV
                     ASGHSLDRQLTITSDILNGEVTGSYSFNTLIPSLMNTFKGYVPALINTTQKKQIVKEN
                     NFALLLTIENTEALSTTLKLPFTMVQPGRITGHYNNIYNKFRIEAWLPKFNLGKSMFE
                     SGYLVCDNPNDKVNLQLKTINYNDKGLRNYLDIKADAKDNLVNTLIGWANNKERLFKA
                     DISASTLFVEEESEKGPAKLRTEVTLNKSPLIIKDTLWTINPANITIREGKIGIEHFR
                     VDHETQYLSMEGTISKDPADTLLVDLKQIELSYVFDVLNIPVLQFGGEATGKFYVNDL
                     FNSRMLNTDLEVKNFSFNQTPLGRLNLFSEWDDAQKGILMLGSIYKNDSTWTDVNGYV
                     FPVGPNAGLSLYFDANDINLAFLQPFVDTVVKNLQGRGFGSIHLHGPFKELNVEGDAY
                     VMDGGVGVDFLDTYYTFSDSVHLDSTSVNLRNITVKDQFGNLGKVSLKFNHLHFRDYS
                     FLVNVQGNNMLMYNANQKKNPLIYGTVFASGTAQIKGNGKLIDFDINMKSEPKTAIYL
                     DFMNKNSATDYDFITFVDKSKLAANVDSTSTHPLNIVHETDEGAELRMNFLLDITPDA
                     DIELIMDPIAGDRIKGNASGSLQIQYGTRSDLRMYGDVNIVQGNYNFSLQQIIHKDFK
                     IRDGSTINFRGDPFNAHMDINAIYNLTANIGDLDQSLLQESSRTNIPVNCVLNLKGAL
                     RSPSISFDLEFPNSNEELERQVKAFIDTEDMMTRQIVYLLVLNKFYTPEYAQTSYKSS
                     ELNAVASSAISAQLSNLLGSFTDKVQIGTNIRAGQDGFKEDTEYEMILSSQLLNNRLL
                     INGNFGMRNTVTTGKNNTFIGEFDLEYKLTPSGEIRLKAYNHARDMYFGLKQALTIQG
                     VGIMYRKDFTNFSEIFRRRKRPLLPLIPKDSTNVPPVVKDSTNLSLPTDKK"
     gene            complement(19685..>19912)
                     /locus_tag="ACZPB4_12135"
     CDS             complement(19685..>19912)
                     /locus_tag="ACZPB4_12135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase family protein"
                     /protein_id="HIR1098994.1"
                     /translation="VLTVNERRDKLVMFHESLMDEYAARLEGGEHQVLSKMKTIWDYL
                     LPEADKRLRKKVLKSTSLTSYQSAVKDLLSL"
BASE COUNT         5684 a         4835 c         4475 g         4918 t
ORIGIN      
        1 tccttccttt tgtaacagac ttatatactc tcgcatccct tccaccaaat ctttctcatc
       61 catatctctc tattttaaat tccaactgaa aacaaacacg cgaaattaga catcctgaca
      121 aattatatct tttgcggcaa gttgttttat tgacgaatag ccactatatt tgtacgttgt
      181 tttaaacaga gtacagacta aattaaaaag taaagcatat gcacaattgg tttgaatgta
      241 aggtctctta cgagaaaatg ctggaaaatg gcatgcagaa aaaagtaacc gagccttact
      301 tggtagacgc cctgtctttt acggaagcgg aagctcgcat catcgaggag atccgcccct
      361 tcatcacggg tgaattcacg gtaacagaca tcaaacgagc tcgtttatcc gaattattct
      421 tcaacgagaa tggtgatcgg ttctataaga tcaaggttta ttttatcacg ttggacgaga
      481 agagtggagc ggaaaagaaa accgccgcac aaatgcttgc ccaagccact acgctgaaag
      541 aggccatcgc cgtattggaa gatggaatga agggtacatt ggcggattat accatcgcct
      601 cggtaacgga aacccagttg atggatgtat tcccattcga tgcgaacagt attcccggcg
      661 agaagaaaag tggcgaggaa ctgatagcgg agcaaaaaca acaagctgaa caaagaggat
      721 aaaaacatga gtatcgctca aaacatagta caactgaaaa cgtcgctccc gcaaggggtg
      781 acgttggttg ccgtctctaa gtttcacccg gtggaagctc tatgggaggc ttacaacgcc
      841 ggacagcggg tgtttggcga aagcagggca caggaactga gcgccaagca aaaagtacta
      901 cctgaggata tcgaatggca ttttatcggc ccgttacaaa gcaataaggt aaaagatatc
      961 gctcctttta ttcatttgat ccatagcata gactccttga agcttttggc tgaggtgaat
     1021 aaacaagcga aaaaacacga ccgcacgatc cgggtattat tggagatcca tgtggcgcaa
     1081 gaggaatcca agcacggact cagtcctgag gaatgcaagg agttgttgcg tgacgagtcc
     1141 tcggccgaat tccagcatat tcgtatttgc ggattgatgg gcatggctac caataccgat
     1201 gatacggggt tgatacggga agaattccgc aatatccatg atttatttat cgaactgaaa
     1261 gagacgctct gtaaagataa tgtcgatttc aaggagatat ccatggggat gagccacgat
     1321 tacccgatcg ctatccaaga aggaagctcc ttgatacggg tgggtaccag tatctttggc
     1381 gaacgggaat attaaagtaa ttattaaatc taaatatagg caacatgatt gacattaaaa
     1441 cccaatacgc ggggttaaca cttcgcaatc cgattatcgt agggagctcc ggactcacca
     1501 ataaggcgga acgtaacagg gattttgaga aagcaggcgc tggagctatc gtattgaaat
     1561 ctcttttcga agagcagatc gagatgcaga gcgaggcttt gatgcaagac tccgattacc
     1621 ccgaagcggc ggattatatc cgtggttatg taaaagcgaa tcaagtaaat gattatctgg
     1681 aactgatcaa gaagagcaag gaattatgta cgatccccat tatcgccagc atcaattgct
     1741 ataaggcgga cgcttggatc gactttgccc gccaaattga gttagcggga gcggacgctt
     1801 tggaattgaa cgtgttcttc atggaaaccg aactgaccga agatttcgag agtatccggg
     1861 atacgtatgt cagtatcatc cgcaaggtaa aagaaaccgt atcgattccg gttatcatga
     1921 agatcggaaa gaattacagc aatattcctt cactggttaa tttgttgaaa gtaaacggtg
     1981 ctgatggtgt cgtgctattc aatcgtttct accagccgga tatcgacatt aataatatgc
     2041 agatcgtttc gggtaatgta tttagcaatc attccgattt gagtgacacg attcgctgga
     2101 cggctatcgt atccggaaag atcccgggaa tcagtatcgc ttcctctacc ggtgtgcatg
     2161 attgggaaga tgtcgttaaa tgtctattgg ccggcgcttc cgccgtacag atgtgtagcg
     2221 ctgtctatac acatggagcg gaaatcatct cccaagtatt gacttgcgtg gaagagtgga
     2281 tgcatcaggc acattaccaa tccctttccc aattccaagg caaattgaat tacgccaata
     2341 tcccgaaccc ggcgatgtat gagcgttcac aattcatgaa atatttctcc aacagagatt
     2401 aaaagaaata cctagtagta gagacggggc gtgccccgtc tcatcaccgt ctgaatagta
     2461 tctttaagtt accatttagc tgggatgaga cggggcacgc cctgtctcta ctatagggta
     2521 atatacaata gtcttaatta ttttccacta gaaagtattt ttattagaaa atagttatat
     2581 ctttgcatca tcaaacaagt tataaagaaa tatggaacca atttgcgcca taaaggatat
     2641 ctataagata ctgtaccagt tcgagaaaaa tttctcggaa gtacatgcta tcaccatcaa
     2701 cgaggccatg ttgctttgtt gcttaaagga taatgaggca aagtcggcag gaatgatttg
     2761 cgattatatc ggtctttcaa actcccgggt ctcaaaggtg atcacctctg tcgagaacaa
     2821 ggggtttatc cgcaggaaca tcaataaaga ggataagcgg caaatgtttt tctcgctcac
     2881 cccaaaaggg aaagagaaaa tacaacagat gatgcaggcc gagctaaata tggatagcct
     2941 gttcaatcaa ctcaaagaat acatacaaaa gggatgaatc ccttttttta actaattatt
     3001 gtctactaac aaatatgtat aatacaaatt aaataaaaat agatatgaag tacttgatta
     3061 ttggaggtgt agctggtgga gctaccgtag cagcccggct gcgtagaatg gacgagaaag
     3121 cggaaatcat ccttttcgaa cgtggaaaat atgtttctta cgcaaactgt ggattacctt
     3181 attatatagg agacacgatc aacgaccgga ataaattatt cgtacaaacc gtgaaaggct
     3241 tcacggatcg attccgcatc gatatccgta cggagcagga agtgacccga atccttcccg
     3301 aatccaagca agtggaggta aagaaactcg gcacaggaga aacctacacg gagacttacg
     3361 ataaactagt gctctctccc ggtgcggagc ctttgcgtcc acgcatcgaa ggaatcgaga
     3421 gtaaaaagat attcacgtta cgtaacgtgc cggatacgga cacgatcaag aattacgtga
     3481 acacggaaaa gccccgtacc gccgttgttg tagggggtgg tttcatcggc ttggagatgg
     3541 cggagaattt gcatgagcta ggtgtccacg tcaccgtcgt ggaaatggct aaccaagtga
     3601 tggcacccct cgactattcc atggccgcta tcgtacatca gcaattgatc ggcaagcagg
     3661 taggcttgat gctggaagat ggcgtatctc gtttcgagga gacttccaga ggcgtgaccg
     3721 ttcatttgaa aagtgggaag cagatcccgg cggatatggt tttattgagt atcggtgtcc
     3781 gtccggaaac ccgattggcc aaggaagcgg gacttacgat cggagcactc ggcggtatcg
     3841 ctgtcaatga atatatgcag acctcgaacc cggatattta tgcgttggga gatgccgtgg
     3901 aagtacgcca cctcgtgaca ggcaaaccag ccttgatccc attggcgggt ccagcgaata
     3961 agcaaggacg tatcgtagcc gataatatcg tatccggcaa taaggaaact tatgacggga
     4021 cgatgggaac ctctatcgcc aaggtattcg acttgacggt cgccacggcg ggagctaacg
     4081 ctaagctgtt gaaacgggaa ggaatcgctt atcaatcctc ctatacgcat ggagcctcgc
     4141 atgcgggata ttacccggga gccgtgcctt tatcgatcaa gatattgttt gcgccggaag
     4201 acggacgact gttaggggcg caagtcgtag gtttcggagg cgtagacaaa cggatcgaga
     4261 tgttagcgca agtgatccag cggaaaggta cggtctatga cctgacggag ttggaacatg
     4321 cgtatgctcc tccttattca gccgctaaag atcccgtaaa tatggccggg ttcgtagcgg
     4381 agaacctgct tacgagaaaa gcgaaagcga tccagtggag agagatccag aacttatcgc
     4441 cagataccgt acgtatcgat gtccgtaccc gtgacgagta cagcttaggg acaatccccg
     4501 gcttcatcaa tatcccggtt gatgagttaa gagaacattt ggcggaacta cccaaggata
     4561 aactgatcgt agtgacttgc gccgttggat taaggggcta tttggcttat cgcatcctga
     4621 ctcaaaatgg cttcacgaat gtccggaacc tatccggtgg ttacaagact tggagtgtag
     4681 cgacagcaaa gatcaagaat gagccggcct gcgcaccttg ttcgtccgaa gctgtttctg
     4741 ataaggcatc tggtaaaagt agctcttgca aatcgactcc ggcagctacg gcgattaagg
     4801 tagacgcttg cggattaatg tgtccgggac cgatcatgca gttgaaaaag aactatgaga
     4861 acttgcggga agatgagtca ttggaaatca ccgcaacaga tcaggctttc ggaaaagatg
     4921 tctcttcatg gtgcaagata accggggcag agttagtctc tctggaaaat aagggaggca
     4981 cgatcgccgc cacggtacga aaaaaaaaag ctgaatgcaa aatagcgaca ggtggtaata
     5041 gtgccgacaa caagacattg atcgttttca gcgatgacct cgataaggcg ttggcctcat
     5101 tcgtcatagc gaacggggct gcctccaccg gaaagaaggt gactatgttc tttactttct
     5161 gggggctcaa cgtgattaag aaacgggaaa aacctgccgt atctaaagat atcttcggca
     5221 agatgtttgg ctggatgctt ccggcaaata gcgaaaagct gaaactatct aaaatgaata
     5281 tgggtggagc cggcagttgg atgatgcgcc ttatcatgaa gaagaaacgg atcgacagct
     5341 tggaaagcct tatggcacaa gccgtagaga atggtatcga gatgatcgcc tgcacgatga
     5401 gcatggacgt aatgggcgtc aaaaaagaag aactgatgga taacgttgtc ctaggaggcg
     5461 tagccaccta tctggaacgt gcggaagacg caaacgtaaa cttattcatc taattcattc
     5521 aaaaaaaata tcccagcata tccacaataa ggacaatgct gggatatttt ataaaaaaga
     5581 gattatacga agtccaatgt tgaacgtttc ataataagag gataacgttc tggatgtttc
     5641 aaactttcga tctccaaatc aacatctaac tccggccatt ctatcgcatt acgcccagcc
     5701 atccgaacat ttaacacatt actaatacgt gcttctttca accatggaac acgattatag
     5761 gacagaaaat aatcccgtcc taacaccgaa agcataatac cctgcgcatt aatcattaat
     5821 acgtttaccg atgtgttcat caaatgattt gatgcttatt taatcatatc aaacccagtg
     5881 taagggatca acgctttcgg gatgcggatg ccctcggggg tttggttgtt ttccaataag
     5941 gcggctacga tgcgaggtaa agccaaggca ctaccattca aggtatggca aagttgcgtt
     6001 ttcttattct cgtcacgata gcggcatttc aagcggttgg cttgatacgt atcgaagttg
     6061 gacacggagc taacttccaa ccagcgttgt tgtgcctcgg aatacacctc gaagtcaaag
     6121 caaagggcag ccgtgaaact catatcaccc ccacaaagac gaaggatgcg atacggcaac
     6181 tccaacttct gaagtaatcc ctccacatga ttcaacatct cttggtgaga ttgcttagag
     6241 tgctccggtt tatcgatccg aaccaactcc accttagaaa attcgtgcaa acgattcaaa
     6301 ccacgtacat ccttgccata agatccggcc tcacgacgga agcattgtgt ataagcgcaa
     6361 ttcttgatcg gtaactgctt ctcatccaga atgacatccc ggtaaatatt tgtcacgggc
     6421 acctccgctg tcgggatcaa atagaggtcg tctacctcgc aatgatacat ctgtccctcc
     6481 ttatctggaa gctgtcccgt accataaccg gaagccgagt tcaccaccgt aggcggcatg
     6541 atctccaagt aaccggcgtc acgggcctca tccaagaaga agttgatcaa cgcacgttgc
     6601 aaacgagcgc cctgtccttt atagaccggg aaacctgctc ccgtgatctt aacacccaga
     6661 tcgaaatcaa tcaaatcata tttcttcgcc aattcccagt gcggaagagc gttcttcgga
     6721 agttccgttt ccatacctcc cattttctct accacattgt cctccgcaga gataccctcg
     6781 ggtacctcat cataaggtac gttcgggatc gtataaagta agttctgcag ctcctcggca
     6841 gcctgatcca tctcaacctg caaagccttg ctcacctcct tgatctcgga aacatgtttc
     6901 ttagcggcct ccgcctcttc cttcttgccc tctttcatta attgtccgat cgacttcgag
     6961 gttgcgttta cctccgctag gttcttatct aattgatttt gtgcgatacg tcttttatca
     7021 ttcaattcca acactttatc gatgctttct ttcgcaccct taaaatgttt cttttccagt
     7081 ccacggatta cggcatccgt gttttcagtg attaatttga ttgtcaacat attctattta
     7141 tgtttaatag tttttctaag acgcgaattt agtaatttta ttttacccta ccacccgtta
     7201 accaagttct tgtataataa ggttcgctaa ggctacttac catcacgcca ctggaagtac
     7261 tggtatggat gaagcgccca tttttcaagt aaatccccac gtgattcgga acgccacgtt
     7321 tcccgccacg acccgtctta aaaaatacca gatctccttc ctgcaatttg gcacgactca
     7381 ctttcttgca attatacttc agcatatccg ccgaggaacg agccagctgt tttccgtata
     7441 cctcccgata aacgatcgat acgaaaccgg agcaatccac gccccgcttc gtacttcctc
     7501 ccaatttatg acgtacaccc aaccaacggg ccccctcgtt gtacaagaat atattatctt
     7561 ccggtgtgat acgtacccca tataagcgag ccaactcctt cggtcccttg aaatcggcgg
     7621 gcaaagctac tttttgttgt tttttgctac cgcacgaggt cagacatata agcaggataa
     7681 agatccggat aaaccctaaa ggaatgctat tcttcatatc gttttctctt aattaaggca
     7741 cgaatataca cataaagttt agaatgccca ttataaggtt cctacaatgg gcattgtaag
     7801 gtcgttagaa tgcccatcgt aaggagcttt gaatgggcat ccaagttcaa gaaggttgag
     7861 cagctttcag ataagcgttg aacgcctctt tgtaggcatc cgtcacgtgg atgatctcct
     7921 ttccgatata aacgcaatta ttccgatcaa cggaacggat cttatccaac gccacgatat
     7981 aagaacgatg tacccgcata aagcgaccgg tagacagcat ctcttccatg gccttcatcg
     8041 tcacgtgggt gataagcgga cgggcctccc cttccagata gatcatcacg taatccttca
     8101 agcccgtcac gtataatatc cgggagattt ccacctgccg caactggcta tccacccgca
     8161 cgaaaaggct gcctctctcc tccttcacgc tattcatctc aaaccattgg cgggccttct
     8221 ccacagctcc gagaaactta tggtatcgga tgggcttcag caggaaatcg agggcattca
     8281 cctcatagct atcaaaggca tactccttaa aggcggtcgt gaagatcacc ctcgtactgg
     8341 gcggtaccat ccgggagagg ttcagcccgt ccagatccgg catctgaata tccaagaaaa
     8401 gcacgtccac cggagactcg cacaacgtgg agagcgccag taccggatca ttgaaggaag
     8461 ccgccagcct cagataaggc gtacggctta cgaagtcctc cagcatcttc accgccaagg
     8521 gctcatcgtc tacgatcatg caagtcagtg ttttcataag cagtctcgaa gtgttatttg
     8581 aacaaagtaa ctattttccc gaagcgcttg atcatatcgg taacgaccgg gataagccag
     8641 atccagccta cgcctcagat tctccagccc gatccccgat ccgctacggt tcacgtccgg
     8701 tttcggatgg tcgctattct cgcaggtaaa gacgaggtca tctccttccg ccttgaagcg
     8761 aatacgtacg aacgacgact tacggctatt cacgccatgc ttgaaggcgt tctctattaa
     8821 agagatgaac aagagcggaa cgatcctcat cggtttaggc gggatccgca gatcaacttc
     8881 cacggtagcc aactcattgc agcgcaatct catcaactcg atgtaattgc tcatgaactc
     8941 gatctcgcct tccaccggta ccagctcatg gttcgactca tagagcgtat accgcagcaa
     9001 atcgctcaat tgcccgatac gttcttgcgc cgtatcttgg tctatctgga ccaagctgga
     9061 tatattattc aaggtattaa agagaaaatg cggattcaac tggttcttca gccaagccaa
     9121 ttccgcctcg gcgtttttct gccgctcctc tttcaaacgc atctgcatat cgccccagcg
     9181 tacgatataa cggaacccca cggcacatcc aatcactagc aaatgtaaga agaacgctcc
     9241 gaaagcgacc atatacattc ccgaacgcca ttcgtccggg aaatccgcct taggagaaaa
     9301 tatccatagg ttagcccccg tgatcaatag caaattcatc aaaccaaaga gcatcttccg
     9361 atcccgataa agcaaatagg gaaccaatac atagaaatta gcggtgaaaa caatagccaa
     9421 cggagtaatg aaccccgtat taatcttcca cacctcgaaa gccgagctcg gattaaagcg
     9481 tatgaaaaaa tcgatcgcag gaggaatcag ccataaggtg atccacaata aagcctgtcc
     9541 tcccgccaat atataatctt gcctcgtgag tttcataata ccgtttttta taaaagtaaa
     9601 cgaatctaac gcctgcgcct atgaacgcaa gcgtttattc gacgaaaggc agggtcgctt
     9661 tagacgaaaa aagaattatc gtttctggat acgagccgca tagcctccac cgggagccat
     9721 atggatcttt aatttgcgat ctgtcgggac tgggattacc tctttcttat aatcacgggc
     9781 ggcacgatcg gcatttatgc catccttgaa taattccaaa gtataatcac cttcgcccaa
     9841 gaaagacagg tctaaatcca gctccctcgg cgtccagttg gtcaacgccc cgatatacca
     9901 atcattacca tgacggcggg cgatcgctac atactcggag acctttccag ccaatgagac
     9961 cgtctcatcc cagatggtcg gaatgttaga gataaactcc gtacattcct tttccctcct
    10021 ataattagac ggggcatcgc acagcatatt gaaaggagac tcgaagatca cgtaagtagc
    10081 caactggcgg caacgggttc cttggctcat cggctccgag tttaccgacc gatgattacc
    10141 tctggcggcg ttacgcatag caccttgcgt ataatccatc gggccggcga tcatacggat
    10201 aaatgggatc gtgacatcat acgtcaccat atcgaactcc ttctcggaag accacttcat
    10261 ttgctccaaa ccattcacac cctcatagtt caacacgttc ggataggttc gttgaagacc
    10321 tgtcggcttg aatacgccat ggaaatccac tagcatctta tatttagcgc atacctcgga
    10381 ggctttataa acaaagttca ccatttcctg atcgtcacga tccaagaaat ccaccttgaa
    10441 gcctttcacg cccatatccg aataatgctt cacgacattc tccatatcac gggcgaaagc
    10501 ccaataacct gcccaaagga taataccgac attcttggat ttaccgtaat ccaccaattc
    10561 ttgaagatcg atctccggta ttacttgcat catgtccgct tgcaggttca cggcccagcc
    10621 ctcatccaag attacgtact cgataccatg ctcggcggcg aagtctatat aatatttata
    10681 ggtgggatta ttgattccgg cacggaaatc cacaccgtat agattccagt cgttccacca
    10741 atcccaagcc accttacccg gcttgatcca agagatatcg tttacccggg agggagaagc
    10801 cagacggtag accatatcgc aatcggccaa ctccttatca ttccgggaga ttataaacgc
    10861 acgccaaggg aaagaacggg ttccggatgt tttggcgata tagttctcac gctctttcac
    10921 caacatctgt aactgattat ggccaccttg ctccttcact ttcggataag gcgcatgaac
    10981 cgctttaaag gaaggttttc ccgtctcgtt attcaagaac atcccgggga aatcctccag
    11041 atcggcttcc gtgatacaga tcttgcgacc atctcccaga tccaccaaaa gaggcaggat
    11101 cttcaggcgt ttatcattca ggccagtgat cgtctcgttt gcgtagggct gctcgaagga
    11161 attgaaaaat tgctcctcga acgtcggctt cgtactattc acgtaagcgg tgaatgtctt
    11221 ataatccgag ggaaaattat agacggcctc ctcatcggca ataacgatcg gttcctttct
    11281 tttcgtcgtg aaacggtaag cgactccatc gttatacacc ctaaaaacca gcccgtagtt
    11341 tccccggaac gagatttgca tctcattata gatatccttt actacgtcct tcttatagaa
    11401 cggagagggt atctccttgt ctaccgaggt cttcgtcact ttcaagactt tcgggttagc
    11461 gccaagtacc tcacctcctt gtaaagtcat agatacggca gaattcatca cctccgaatg
    11521 atcctgtacg atagcgaaag tgactttatc ggctaccgta acctccacct ttatatcccg
    11581 gttcggagac tggacttggt aattcttctg ggcgatcgac gggatagcgc ccattaaaaa
    11641 gagaaaagca aatagaatgt ttttactcat ggtttattga tttaagtttg tttatgaata
    11701 caaatatata ttatctttgt catattcata acaaaaaaca aataataccg aaatgatgag
    11761 acttcacaaa atcctcttaa cgctcgtatg tttcacggtt ctctccgccc acgcacaatg
    11821 gaaatggctc aacccgctcg aatgtggatt ccctgtcata caaaaccaag gatggaccga
    11881 agagatcgga gaccgttacg ttcggcttcc ccaaagagcc gaaggcaagg tacgtaaacc
    11941 cgtctgggat ttatcgcgca actccgccgg gttggcgatt cattttttca gtaacgcccc
    12001 tgaactaaaa gtacgctatc aagtaagcgg accgctgaat atgccacata tgcccacgac
    12061 aggcgtatcc ggtgtagatc tatatagtat cgatagcgat ggccaatgga gattttattt
    12121 cggcggttat ccttccggag atacgcttca atatcattat acgaacatag gcaaagatct
    12181 gtatcatgac aggggctatg agttccgcct ctgcctgcct ccttataata cgataaagtg
    12241 gttggaaatc ggcgtgcccg aaaacgatga gcttacgttt atccccgtat cgcccgagaa
    12301 accgattctt ttatacggaa cctcgatcgc ccaaggcgca tgcgcctccc gtccgggcat
    12361 gacttggggt acgatcttgc agcgttcact gggatatccg cttatcaacc taggcttctc
    12421 cggtaacgga cgtttagaga aagaggtatt ggattttatt tgtgagatag acgcacgcct
    12481 ttatatcctt gactgcctgc ccaacctcac gccaaagagc aaagatgaga tcacgcaact
    12541 cgtatcggac gcagtcaagc aaatacgtgc cacccactcc tctccgatct tattggtgga
    12601 gcatgccgga tatagcaacg cactcgccga cgatacgaag ctacaagatt atgtgcgcat
    12661 gaacgaagga gctaaaaaag cattcgagga attgcaggca caagggataa aagatatcta
    12721 ctaccttaca cgagaagagc tgggactgca cccggatgct tgggtagatt acgtccatcc
    12781 ttccgactgg ggcatggaaa cacaagcgaa cgccgtagag cggaaagtac gggagatatt
    12841 acgcatcccc aaaggagacc tctctaccac aatgcctgtc acccagcgcc gggaacccaa
    12901 taattacgaa tggcaaaaac gtcaccggga tattctctcg ctgaatcaaa gcaacccgcc
    12961 tcgacgggtg atcctaggta attccatcac gcatttctgg ggaggagagc ccaaaggacc
    13021 gtccgtgcga ggtatggaaa catgggagaa aatcatgcgt ccggctggat tccacaatct
    13081 cggatatggt ttcgaccgta tcgagaacgt actttggaga gtctatcatg gtgaattgga
    13141 tggatacaag gctgaggaag tagtattgat gatcggcacg aataacatcg gaatcaacaa
    13201 tgacaacgag atcgtggaag gcattcgttt cttgctttcc gccatcaggc aacggcagcc
    13261 ggaggccaag atcaaggtaa tcggcatctt gccccgccgt aaccaagaag aacgggtaag
    13321 gaatctcaat ctccgcatcc gtcaaatagc cgagaccgga tggtacacgt tcaagaaccc
    13381 gggtacgaag ttgcttcagg aagacggcaa gataaacgaa tccttattct cagacggatt
    13441 acacccgaac gaggaaggct ataaacgaat cgtggacgag atcgcccatt aagcgatagt
    13501 ccctttactc acgaatcaat ctgagcaaca tacgcaacgc cgcctctgcc gacaagcgaa
    13561 tgttctccat acgaggattc tccccgaaat gatagcactc ggagagaatc ctctccttat
    13621 aagcggcggc aatccatacc gttcccaccg gtttcgaggg agtcccgcct cccggcccgg
    13681 cgatcccgga ggtagcgacg gcacaatcac atcccaatac ccgcatagtt ccacgggcca
    13741 tctgctccac aaccggctgg cttacggccc cgaaagtgtt caagtccgcc tcggagacac
    13801 cgagcacatg atgcttcacc tcgttgcaat aggctaccac gcccccggtg aagtattccg
    13861 agctgcccgc catggaggtt atcatgctgg caatctttcc gcctgtacaa ctctctgccg
    13921 tacccatcat caggtgtcct gatttgagtg cgtccgctac ctctaactct attggtaaat
    13981 catctacttc cattgttata atgatactag gagtttcatt atgggaaaac aatagtttca
    14041 ttaggaagaa acttttgttt tccctagaag aaacttttgt ttctctatag caaaactatc
    14101 ttttcctata agacaaccct agaaaaagga gcggcatcca tcggacagaa ctccttatcc
    14161 atatacttat aatatcccgt gatagctacc atagcggcgt tatccgtggt gaacgagaac
    14221 ttcgggatat gcactttcca gccataacgt tttgcgtgat ccaagaatgc ctcacgcaaa
    14281 ccggaattgg ccgatacacc tccggcgaca gctacttcct ttatatgcaa atccttcgcc
    14341 gccttacgca atttactcat caagatatcg attaccgtag cttgcaagga agcgcatagg
    14401 tctcgcttgt tcttctcaat aaaatccgga tcatctttca aatgatcacg caaggtatat
    14461 aaaaaggagg tcttcaggcc actgaagcta taatcatatc cggggatatg cggcttgctg
    14521 aacgtaaagg cattcggatt accctcgttc gccaaacgat tcacgactgg gccaccagga
    14581 taacccagtc ccatcacctt agcgcatttg tcgaaagcct ctcctgcggc gtcgtcgatc
    14641 gtctggccga tcacctccat atcattataa gcgttcacct ttatgatttg cgagttaccg
    14701 cccgaaacca acaagcaaag gaaaggaaac gagggagcat ggtcatcgtc cggagtctcc
    14761 ttgataaaat gagccaacac gtgagcctgt aagtgattga cctcgatcat tgggatatcc
    14821 aaggaagcgg ccaaaccctt ggtgaacgag gtcccgacca ataaagaacc catcaaaccc
    14881 ggtccacgag taaacgccac ggcactcaac tcggacttat cgatgccggc acgcttgatg
    14941 gcctcggcca ctaccggaat gatattctgc tgatgggcac gggaagccaa ctcggggaca
    15001 accccgccat aagcctcatg aacggcttga ctggctatta cgttggacag catcacgccg
    15061 tcacggatca ccgaagagga agtgtcatcg caagaagact cgattcctaa tatcgttata
    15121 ctcatatctt cattcttttt tccgcgaatt aacgaaatct atcgcgatat tgttgtagat
    15181 ttgcgctaaa taaatagaaa agatatcaga ggacttaaat acataatcat taccctgctt
    15241 acattattct ggatattcta tgcgttgccg ggcatcttac tgagaattcc ttatattcaa
    15301 aacaaagtat cagaagtagc cacgacccag ttatccggcc acctcggtgt gcccgtaaag
    15361 atcggtaacg tggatatcga atggttcaat cgcctagtac tggaagggct ttatctggaa
    15421 gaccaagacg ggaaagtcat gttcgaggcg aaccatgtgg cggcgggatt cgagatcatg
    15481 ccgttactgg aagggaagtt cgtcttcacg acggtacgtt tgttcggttt ctccttcaac
    15541 ctacgaaaac atacgcccga aagccccttg aacctgcaat tcgtcatcga cgctttcgcc
    15601 agcaaggatt cgataaagaa agagaagaat atcgatctcc gtttcaactc catcatgatc
    15661 cgaagaggta atttcagcta taacgtggat agcgagaaag agaccccggg aaagttcaac
    15721 gccaagcata tcgatatcaa gaacctgagt gccaagatat ccctcaaggc ttttaacaag
    15781 gacagcgtga acgcccatat caagaagatg agtttcgatg aggcatccgg tttctccttg
    15841 aataagttat cgctgaacgt ggtcgggaac cgggatagcg ctttcgtgca ggacttcgag
    15901 gtacgcttgc cgcagacaga cttgaagatc gggcgtgccc ggatcgattt aagcgagatc
    15961 gatagccttc ccgctctctt gaacaacgct ccgatcgatt tgaatataac accttcgcaa
    16021 atctgcctga aagacttatc ccctttcgtc ccggcgttca agaacttcgc cgacacgatt
    16081 gagttatcgg ccgaggcaaa cggctacatc aataatttta acttgaagcg cctcaccttg
    16141 aagtatagcg ataagatgct gtttatcggc cagatggaac tgaaaaacat cacccatccc
    16201 gaggaaacgt atcttttagg gaaggtgaat aagatgtata tcacgacaga cggcatctcc
    16261 agtctggcca ataacttcaa tgagcgtccg aagagtctcc cggccccggt cgtcaaattg
    16321 gggacgatca atttcacggg cgagatatca ggcttttttg ataacctagt cgctttcgga
    16381 aaattatcgt cttccatcgg ctccatacag acagacttga tattcggtag caacaaggat
    16441 aagaatatag ccgcttacct acggggacgc atcgcctcca gcaacttgcg gctccatgag
    16501 ttatttggtg agaataatcc tttcggggag gctcgcttcg acatcaatat cgatacccgt
    16561 agacctgttg gcggaaattt ctccggaaat atccaagcac aagtcaagga gttcgattat
    16621 aaagcttata aatacaagga tattaatctt tccggtaatt tcaggaaaag tagtttcgat
    16681 gggactatcc atgtagacga tcccaatggc gagttacacg cccaaggcat cttccagcac
    16741 caagggcaaa actccttgtt taatttcacc gcccgcctcg atcatttccg gccggaccga
    16801 ttgaacctga cagacaaata tgaggcgccg aatatctcct tggctttaaa cgcggatttc
    16861 accggagata atatcgataa tctggaaggt agcatcacgt tggacagtct ttctttcgag
    16921 accactccca gcagcttctt ccttaagaaa ttcgaagtag ttgcctcggg gcatagtctc
    16981 gaccggcaat taaccataac gtccgatatc ttgaatggag aggtcaccgg gtcttactca
    17041 ttcaacacgc taatccccag ccttatgaat acgttcaagg gatatgtgcc agccttgatc
    17101 aacacgaccc agaaaaaaca aatcgtgaaa gagaataact tcgccctcct attaacgatc
    17161 gagaatacgg aagcgctttc tacgacatta aaactaccgt tcacgatggt gcaacccgga
    17221 cggatcacgg gacattataa taatatttat aataagttcc gtatcgaggc gtggcttccg
    17281 aagttcaatc tcgggaaatc catgttcgaa tccggttact tggtctgcga caatccgaac
    17341 gataaggtaa acctccaatt aaaaacgatt aattataacg acaagggact gcgtaactac
    17401 cttgatatca aagcagacgc taaagataat ctggtgaaca ccctgattgg ctgggcgaat
    17461 aataaagagc ggttatttaa ggccgacatc tccgcctcta ccctttttgt cgaagaggaa
    17521 agcgagaaag ggccggccaa gttacgtacg gaagtcacgt tgaataaaag ccccctcatt
    17581 attaaagaca cgctctggac catcaatccg gcgaatataa cgattcgtga gggcaagatc
    17641 ggtatcgagc atttccgggt agatcatgag acccagtatt tatctatgga agggacgatc
    17701 tcaaaagatc cggcagatac tttattggta gacttgaagc aaatagagct gagttatgtc
    17761 ttcgacgtat tgaatatccc agtcttgcaa ttcggaggtg aggctaccgg taagttctac
    17821 gtgaatgatt tattcaatag ccgtatgcta aacacggatc tggaagtaaa gaatttctca
    17881 ttcaaccaaa cccccttggg tcgcctcaat ctcttcagcg aatgggacga cgcacagaaa
    17941 ggtatcctta tgctgggaag catctacaag aacgacagca cttggacgga tgtaaacggc
    18001 tatgtattcc cggtcggacc caatgcgggg ctatccttgt atttcgatgc caatgatatc
    18061 aatctagctt tcttgcagcc ctttgtcgat acggtcgtaa agaacttgca aggccgggga
    18121 ttcggaagta tacatttgca cggccccttt aaggagctga atgtcgaggg agatgcctat
    18181 gtcatggatg gaggggtagg cgttgatttc ttggatacgt attatacctt ctccgattcc
    18241 gtccaccttg actctacatc cgtcaattta cggaatatca cggtcaagga tcaattcggc
    18301 aacctaggga aagtcagcct caagttcaac catttgcatt tccgggatta tagcttcctc
    18361 gtaaacgtgc aaggcaataa tatgttgatg tataacgcca accagaaaaa gaatccgctg
    18421 atttacggaa ctgtattcgc cagtggaacg gcgcagatca aggggaacgg taagttgatc
    18481 gactttgata ttaatatgaa aagcgaacct aagaccgcta tttatctgga cttcatgaat
    18541 aagaactcgg ctacggacta tgattttatc acgttcgtcg ataaaagcaa gttggccgct
    18601 aacgtagatt ccacgtccac acacccattg aatatcgtac acgagacaga cgagggagcc
    18661 gagctacgaa tgaacttcct ccttgatatc acacccgatg ccgatataga gctaatcatg
    18721 gacccgatag cgggagaccg tatcaaagga aacgccagtg gaagtttaca aatacaatat
    18781 ggaacaagaa gtgatcttcg tatgtatggc gacgtgaata tcgtacaagg aaactataat
    18841 ttcagcttac agcaaatcat ccataaagac tttaagatca gagacggtag cacgatcaat
    18901 ttccgtggcg atccctttaa tgcccatatg gatatcaatg cgatctacaa tctgaccgca
    18961 aatatcggag acttggatca gagtctctta caagaaagtt ctcgaacaaa catacccgtc
    19021 aattgcgtct taaaccttaa aggcgcattg cgcagcccgt ctatttcctt cgacttagaa
    19081 tttccgaact ctaacgagga attagagcgt caagtcaaag cgtttataga cacagaggat
    19141 atgatgactc ggcaaattgt ttatttgctg gtgttaaata aattctacac accagaatat
    19201 gcccaaacga gttataagtc tagcgagtta aacgccgtgg cttcatccgc tatctcagcg
    19261 caattatcca atctattagg tagtttcacg gataaagtac aaatagggac aaacatacga
    19321 gcgggacagg acggtttcaa ggaagacacg gaatatgaga tgatattatc cagccagttg
    19381 ctaaacaacc gcttattgat caatggtaat ttcggtatga gaaatacggt cactacaggc
    19441 aaaaataaca cttttatcgg agagttcgac ctagaatata agttgacccc ctccggtgag
    19501 atccggctaa aggcttataa ccatgccaga gatatgtatt tcggcctgaa gcaagcatta
    19561 accatacaag gtgtaggtat catgtaccgg aaagacttca cgaacttctc tgagattttc
    19621 aggagaagaa agaggcctct tttacccttg atccccaaag actctacgaa tgtccctccc
    19681 gtagtcaaag actcaacaaa tctttcactg ccgactgata agaagtaagg gaagtacttt
    19741 tcaatacttt cttgcgaagc cttttatcgg cctccggcaa aagataatcc cagattgtct
    19801 tcattttaga taatacctga tgctcgccac cttccaaccg ggcagcatat tcatccatca
    19861 acgactcatg gaacatgact agtttatccc gcctctcatt cacggtcaag ac
//
LOCUS       DBMDTB010000077        19561 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_932_length_19561_cov_10.563155, whole genome shotgun sequence.
ACCESSION   DBMDTB010000077 DBMDTB010000000
VERSION     DBMDTB010000077.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 19561)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 19561)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19561
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_932_length_19561_cov_10.563155"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..3114
                     /locus_tag="ACZPB4_12140"
     CDS             <1..3114
                     /locus_tag="ACZPB4_12140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008771785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SusC/RagA family TonB-linked outer membrane
                     protein"
                     /protein_id="HIR1098995.1"
                     /translation="NVVVKGTTNGTITDLDGKYSLEVEPNSILVVSYIGYVSQQIPAS
                     GSVVNVTLKEDTQNLDEVIVVGYGTQQKKDITGSVAVVDTKELLASSGSSAAQQLQGK
                     AAGVYVGQSGSPGSATMVRIRGINSVNDNGPLYVIDGVSTRNQNMSSLNPNDIESMQV
                     LKDASAAAIYGAQAANGVILITTKKGTKSGQPKVTYDGYIGMQKTTKRYEVLNSADRL
                     ALEWESQQNSYTIRGVDEVPEHPQFGKGPKPIIPNYLTTNGAQGSQNINMDDYSYPDN
                     QIVPFSDTDWWDAVDRTALMQNHQIGLSGGTEKGTYNVSANYFKQDGTVIDSYYQRYQ
                     VRANTSFNIRPWLRAGENMTYAFSKDNGLQAAAAESSAYSWTYRASPWVPVRDTHGNY
                     AGSKITGTGNFQNPVAIQERNKDNYWTNSRIFGNLWAEADLFKGLTFRTNFGLDYTNN
                     YSYRMDKKNLEFSESPGTNNLEEISGFNFRWVWTNTLTYSTVFKDVHKLNVLLGTEAI
                     RDGIGRKMTGQRFGYLMEDNMNTWVLNMGENDARRRAESEYKGEFALFGMFARVDYSF
                     ADKYLITGIVRRDGVSRFAKANRYGVFPSVSLGWRISEESFMENTKDWLDDLKLRVGY
                     GQTGNSEMSRKTNYAFEYATKSTNTNYDLGASNSGSMVGFRLDKYGNEDTKWEATEMT
                     NVGLDASFLNGKFGLGFEWYYKKTSDMLIEAAYSGLAGSEIGKPYLNYGDMKNTGWDL
                     TFNYRDSKGDWGWDIGVNASAYKNEVLKLSNTDDFFIGKAGARFEGEHVTRTTKGQPI
                     SSFFGYNIIGFYESADDVKNSPLPYGISSKEELKPEQMVGKFKFEDRNGDGKVNGEDR
                     TFIGSPHPDLILSLNASATWKNWDFTMFWYSTIGNDIFNNTKYFTDFPLFGGNRSTRM
                     RDLSWRPGADNSKAILPILDSKDSWSGAVPSSYYVEDGSFLRLKNVVLGYTFPKSLLQ
                     KATISNLRVYIQAENLLTISGYSGLDPEFTNADVGEGNGADLRRGIDMGGWPTTLRLL
                     FGVNFAF"
     gene            3157..4911
                     /locus_tag="ACZPB4_12145"
     CDS             3157..4911
                     /locus_tag="ACZPB4_12145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0019867 - outer membrane [Evidence IEA];
                     GO_function: GO:2001070 - starch binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RagB/SusD family nutrient uptake outer membrane
                     protein"
                     /protein_id="HIR1098996.1"
                     /translation="MKQKYIALLACASLLTLGACGEDFLYKAPQGAIDKEALTNANGV
                     DLLVTNAYANLTENGWGASVFNWTFGGMYGGDANKGSDGNDQSILNTMEMYNMLPSNG
                     YLNEKWEWVYKGAKRVNNTLQIIPAVTDMPENVKNTRVGELKFLRALFYFEGIKVFGP
                     MIPWVDETIEENNPLVHNDKDIYQNVLTDIDDAISKLPETQDMVGRVNIWAAKALKAK
                     ILMQKGDMASAKPILKEVIESGKTSNGLAYGLENDMNANFDSFRDNGKESIFAIQFSV
                     DANDNGNSGMSLCYPHGGSGNPGGCCGFYQPSSELANSFKVDANGLPLLDNSYRAGKP
                     VSYRNSSTNPEDPIALNNDEIAVDPRLDFAIGRFGIPYKDWGTPKNGWVRDAANGGIY
                     LPKKHVYSKAEEDAGLASGGFSGGWAPGSAMNLQYLSLRDCILMYAECLANDGQLAEA
                     MSQVNKIRVRAGLDVNIIKKDGKPAANYKIAEYPSSHAAFSDKNTCIKAVRMERKLEL
                     AMEGQRWFDLQRWGGDYMAKTLKEYVDFEKGYLAKFSTASYLPAAKVMFPIPDQQIST
                     MGNDESGQPYLVQPAPWK"
     gene            4996..5385
                     /locus_tag="ACZPB4_12150"
     CDS             4996..5385
                     /locus_tag="ACZPB4_12150"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1098997.1"
                     /translation="MRKILLVIFACASMQLGFAEVENDKDVIIEDVTEMSVNAVNVVY
                     EVDGPTSYALNGSTSGVGSSYSIAPLPPANATFSWKLQGGGRGYIYPNQYNCGINLYD
                     AGSYRLSCIITINGVKTESATYITVTP"
     gene            complement(5756..6253)
                     /locus_tag="ACZPB4_12155"
     CDS             complement(5756..6253)
                     /locus_tag="ACZPB4_12155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HIR1098998.1"
                     /translation="MEISVFIREYAPLAGEAGRAFRIDPVVILAQAAIETGWGESTLC
                     REYHNFFGITAYGLPNVWWTGRWTELSPRSLRFRIYPDDKCSFMDYCRLLRSAYPRAA
                     DMSANPTAFAKEIAYSPYISEVNGDNREAYRKLIVQLCRKISSQLSIVNPKGGQMPPL
                     SSTVN"
     gene            complement(6295..6753)
                     /locus_tag="ACZPB4_12160"
     CDS             complement(6295..6753)
                     /locus_tag="ACZPB4_12160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HIR1098999.1"
                     /translation="MIRYKKYQNKNEKNETTFNKWYARAVCEETVDIAALAEHMSTHN
                     TPFSTGAIHGMLKDMVNCIKELLMDGKNVKIDDLGIFSVGIRSKGAVTPEDFSTQGNI
                     IGVRLRARATGNLSSASLKLTAKLREYTEYSNGEVTPGGGGGDSESPDEI"
     gene            6895..7116
                     /locus_tag="ACZPB4_12165"
     CDS             6895..7116
                     /locus_tag="ACZPB4_12165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4248 domain-containing protein"
                     /protein_id="HIR1099000.1"
                     /translation="METTFKIRAYGRMELAEVYLPDLHPRSAHRKLQHWITIYPGLPG
                     RLRSLGYHEGERVYSPAMVRAIIESLGEP"
     gene            complement(7418..9574)
                     /locus_tag="ACZPB4_12170"
     CDS             complement(7418..9574)
                     /locus_tag="ACZPB4_12170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="virulence-associated E family protein"
                     /protein_id="HIR1099001.1"
                     /translation="MINTSLFALFGRYKGDASLAGVLENIQRGTYKQFIDETREALAS
                     GDKELAAKLKKKLPAFTPQATYSGKRLDPHITRYNQLVVLDIDHVGERELERITPLAT
                     EAPYTVAYFRSPSGDGAKLIAYAATDETATPGNHRRVYEAMSRWYAARLGVELDTSGS
                     DIGRLCFVSDDPALYLSPAYRPWLEGTGELPEGLAPLPLTWKEEVSETAPGAKERKVA
                     SPLEKARRTAERKGAYAEGNRNNFIFVMAARANRLGVKRAEMEAYAATAFADLPAEER
                     LAAIESAYSHVEEHAAETSAATSRKKGGGPLDVVAVEAYISERFLTRKNGVRGYVEVA
                     TKKKRNGQKPVFKPVTDYWVNSLWRSLLKDGHYCSHNDIRAILMSDFSETFHPFRSYF
                     EGLAPWDGVTDWIGQLADTVDTTRPAFWRGCLKRWLIAGVAGSMELGVENHTILLLAG
                     GQGLGKTSWLRNLVPPELRDYLFTGNVNPYSKGFPQMMVDCLLIVIDEMSGQSYADLN
                     RLKALTSTGVIYLRRPYGHYAETQIRHASFAATVNDLQSLPDDNESRRFLCFEATRID
                     YQSPVRHADIYAQALALFRRGEKYWFSGEDIRKINENNETFRQRSPEEELFFTYFRKP
                     ERFDTPQYLTASDIMTKLSVFTRITPTRSNIVTLSKVLKKHGFKLTKTRGKLLFEVAE
                     ITSEQVKANFLRPRQEEEDRAQKENDIFKGQEDKPE"
     gene            complement(9694..10038)
                     /locus_tag="ACZPB4_12175"
     CDS             complement(9694..10038)
                     /locus_tag="ACZPB4_12175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099002.1"
                     /translation="MRKLLDSLENAQKAWVDLKKDAKGAHKLFKDYQPEEDLVKREKI
                     IYTGSVKDFVRLTLPILDDQRFRVNGQTNREAMIRALDEVFEIHPNGCPEPRSFRSIL
                     STAQEEYGKAHE"
     gene            10202..10894
                     /locus_tag="ACZPB4_12180"
     CDS             10202..10894
                     /locus_tag="ACZPB4_12180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099003.1"
                     /translation="MRKLLGFLCVCALAIVTARAQDAVDDYVSSAAGQSVIYHGKEQL
                     KYPTSIRNHPYLKSEKYVPGDLSFEGILYKDVKMRLDLYKNELLLFSPDNRYNIVLPS
                     DRVDYAEFHGYHIFYRYPDERSGNLPEGYYLRLYEGKCTVLGKWSCILSKTIKDMKLD
                     DSFDQSVKYYIRKEGVYYTVRSKGSVLKVLKSKKKELARYIKRRKLDFKHAPEEAIVA
                     VVRQYEQLNEIP"
     gene            10891..13644
                     /locus_tag="ACZPB4_12185"
     CDS             10891..13644
                     /locus_tag="ACZPB4_12185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HIR1099004.1"
                     /translation="MRKSLYIGMVMCLLSGWTARAQRTVDLDFRQVTLNVVFNAIERQ
                     TGQPVYRQPLETDSMVVSVHSEKEEPLVALRRALEGTPFQVSSYGGAFFVLRDNTLMT
                     SLPENFFLREKRREGDGDEEGSGISLMAGRKQQKATSENKVYEIGDASGKAADRVTVT
                     GNISDFKTGEPMVGVAVFVKDPMIGATTDAYGYYTLRLPPGRHELYIQGMGMKDTRRQ
                     IMLHSDGKLDIELEEQVYTLKEVTISSEKIANVRNTTMGVERLKVKDIKNIPMAFGEV
                     DIMKVVMSLPGVKAVGEASSGFNVRGGATDQNLILFNDGTVYNPTHLFGFFSVFNPDV
                     VKDMELYKSSIPAKYGGRISSVLDINSREGNKKEFKGSASIGLLTSRLTLEGPLFSEK
                     TSFIVGGRTTYSDWILKKLPEKSGYKDGNAGFYDLNATINHKFDERNNLYLNGYYSHD
                     RFRFNADERYAYENANASVKWRHIFSDRFTGVLTAGYDHYGYNTRNTDNPVNAYSLAF
                     RIDQMYGKMDFTHYLSDKHTLDFGASSLFYDLEPGKYLPYGGESLVKEDRMEKEKAVE
                     SAIYVGDRWDITSQLSLNVGVRYSMFNVLGPRTYNLYADDQLPSLATVTGTVDKTGAF
                     KTYHGPEFRVSARYAFTEDFSVKAGFNTMRQNIHKLSNTTIMSPTDTWKLSDANIKPQ
                     TGMQVAAGLYRNFLNNTIEVSLEGYYKTMKDYLDYRNGAELLMNHHIETDVLRTEGRA
                     YGVELMVKKTQGKLNGWVSYTYSRTQLRQNDPMIVNPVNKGDWYAADFDKPHDLKFVG
                     NYKFTHRFSFSLNCDYSTGRPITLPVSKYHYGGGEFVYYSDRNQYRIPDFFRMDASFN
                     IEPSHHLTLLTHSTISFGVYNLTGRKNAYSVYYISENGKLKGYKMAIFGVPIPFVSYN
                     IKF"
     gene            13657..14817
                     /locus_tag="ACZPB4_12190"
     CDS             13657..14817
                     /locus_tag="ACZPB4_12190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4249 domain-containing protein"
                     /protein_id="HIR1099005.1"
                     /translation="MRKEAKIKDSIKGFHWWLGALLLLLSACVTDYEPKGLEQVRDLL
                     VVDGIITNGETTIKLRRSVGLTDDFTEDEFVNNAKVVVEREDGAVFTCANSSGKGEYK
                     VDMGELDPGSRYRLHISLDGLEYESDYLGPEITPPIDSLSLLKKGPGEEVRLCVSTHN
                     APDRSSYFRWMYKENWEVKAEIFMAAEKMGNTVVIYDLLTSNNWYYCWGKDSSKVISL
                     GSSDRLTQNVIANKSIASYHPSDRRFSMLYHAEVEQYALHREAYDYYFNLQKNIEESG
                     SLFAPIPSEMKGNIRCVTDPEVPVIGFVEVATVTRLKRFFPEIEKVYEAEVTGCASTI
                     VQGSEYDNNPDYGYVSYNPMNAASNTYALKRCMDCGRFGSKQKPSWWPTSHL"
     gene            14828..>16332
                     /locus_tag="ACZPB4_12195"
     CDS             14828..>16332
                     /locus_tag="ACZPB4_12195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099006.1"
                     /translation="MKKSMIKQCILSLLCLLWAGQTVLAGELRERVYLQTDKQFYLSG
                     ELVWMKFIATDLDQRLSDVSKVGYVELLDSASAVVQARLVLEKGVGNGCLQLPSTLPT
                     GNYRLVAYTRYMRNEGEEVFFEKPLTVVNTFVTNEALLTDTLLPTYSFTRREGPVSVS
                     PDRMTYDTRSGGEIRINGLPPDLQTLSVSIAGIDLYKPSARSGIVDWKQSMPTTGSSP
                     ADHKFLAEYEGPILTGKVIDLSTGEPSSKEAVRPLLGFSGGEIRLFGGQLGAAGEVTF
                     FTKHISGTHEIVTVALSPSSSRYRVDIESPYATHPEKELPALRLNPAWQDELVKRSVG
                     LQVLHAYRSDSLVREKAEKPWFQWQPDWSYLLDEYTRFTTMEEVVIEFIPGLRFRKMD
                     GVRRLAVLTEERIGYTIGNSLVLLDGIPITDHEIIFKYDPLKIRKIDVYKGKYVFGGQ
                     IFDGIASFSSYEHNYPGLVVDNSTQFFDYEGTQAQRIFYMPAYRTEAEKRSP"
     assembly_gap    16333..16432
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            16436..17458
                     /locus_tag="ACZPB4_12200"
     CDS             16436..17458
                     /locus_tag="ACZPB4_12200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004793 - threonine aldolase activity
                     [Evidence IEA];
                     GO_process: GO:0006567 - L-threonine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine aldolase family protein"
                     /protein_id="HIR1099007.1"
                     /translation="MRSFASDNNSGVHPRVMDAIIKANDNHAVGYGDDPWTEAATSKI
                     QEVFGKDASPFFVFNGTGANSVALQAVTRPFNSILCAETAHINVDECGAPARMTGCAI
                     VTIPTTDGKLTPELIRPHLKNFGVCHHSQPKAVYISQVSELGTIYTIEEVKAIADLLH
                     SYDMYLHMDGARLANACAYLNCTMRQVTVDAGVDILSFGGTKNGMMMGEAVVSFRPEI
                     TENLRFYRKQSAQLASKLRYLSAQFIPYLENNLWLENAMKANISAAKLADVLRQYPEI
                     HFTQKIESNQLFFTIPAEALRKLQDKYFFYMWNEEINEARLVTSWDTSGEDIAEFEQS
                     LKEIFG"
     gene            17473..19359
                     /locus_tag="ACZPB4_12205"
     CDS             17473..19359
                     /locus_tag="ACZPB4_12205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HIR1099008.1"
                     /translation="MNINIRSNPMRKWFIWAIVMIGCLPINKALAQQSGDAERNTLRI
                     MSYNIRNGRGMDEVTDLGRIAEAIRKVAPDVVAVQEVDSVTGRSGGIDVLRTLGERTL
                     MFPTYAPAIDFDGGKYGVGMLSKEKPVSYRYIALPGREEERVLLWVEFERYIFCCTHL
                     SLTPEDRMLSLPILRREAASAHKPLFIAGDWNATAHSPFITEISKDFQLLSNPKQATF
                     PAFTPDSCLDYIAGYVKNGQPFTRLSAWVPEEAVASDHRPVVTEVRLKAKPEEIFYAA
                     PYLQNPTEGGITVMWQTHVPTYSWVEYGTDTLNLKKARTIVDGQVICNGLHNKIRLTD
                     LRPGQTYYYRVCSQEIMLYQAYKKEFGETAVSPFYTFKVPSASQKDFTALIFNDLHKQ
                     IPTLEALYEQVRDIPYDFVVFNGDCIDDPANEKEALYHLAYLCGKVGASHVPAFFLRG
                     NHEIRNAYSIGLRALFDYVGDKTYGAFNWGDTRFVMLDCGEDKPDSTWVYYGLNDFTG
                     LRKDQVSFLSKELNGKEFKQASKRVLLNHIPIYGNGDAYEPCPELWGSLLAKAPFNVN
                     ISAHTHQYAFHPKGSLGNNFPVIVGGGYKLDSATVMVLRKKGNEMSLRVLSAKGETLL
                     DLKL"
     gene            19368..>19561
                     /locus_tag="ACZPB4_12210"
     CDS             19368..>19561
                     /locus_tag="ACZPB4_12210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute carrier family 23 protein"
                     /protein_id="HIR1099009.1"
                     /translation="MDTDLIYGIDDRPPLKETLFAAIQHLLAIFVAIITPPLIIAGAL
                     KLDLETTGFLVSMALFASGVS"
BASE COUNT         4604 a         4416 c         5461 g         4980 t
ORIGIN      
        1 aatgttgtag taaaaggtac tacaaacggt acgattaccg accttgacgg taagtattcc
       61 ttggaagttg agcccaactc cattttagtc gtttcctaca tcggttatgt atctcagcaa
      121 attcctgctt cgggcagtgt ggtaaatgtt accttgaaag aagataccca gaaccttgac
      181 gaggttatcg tggtaggtta cggtacgcag cagaagaagg acatcactgg ttctgtggcg
      241 gtagtcgata cgaaagagtt gctggcctct tcgggatctt ctgcggctca gcagttgcaa
      301 ggtaaagctg caggtgtgta tgtgggacaa tctggttcac cgggttcggc cacgatggtt
      361 cgtattcgtg gtattaactc agttaatgac aatggcccgt tgtatgtaat tgatggtgtt
      421 tctactcgta accaaaacat gagtagcttg aacccgaacg atattgaaag catgcaggtg
      481 ttaaaagatg cctctgctgc ggctatttat ggtgcgcagg cagcgaatgg agttatcttg
      541 atcactacga agaagggtac taaatcagga cagccgaaag ttacctatga cggttatatc
      601 ggtatgcaaa aaacgacaaa gaggtatgag gtgctgaact ctgcggatcg tttggcattg
      661 gaatgggagt cacagcagaa ctcttatacg attcgtggcg tagatgaagt cccggaacat
      721 cctcagttcg gaaaggggcc aaagccaatc attccgaatt atctgacaac aaatggagca
      781 caaggaagtc agaatattaa tatggatgat tatagttatc ccgataacca aatcgtacct
      841 ttctcagata cggattggtg ggacgctgtt gatcgtacgg ctttgatgca aaaccatcag
      901 ataggcttat ccggaggtac agagaaggga acatacaatg taagtgcgaa ctactttaag
      961 caagatggta cggttattga ttcttattac cagagatatc aagtacgtgc gaatacatcg
     1021 tttaatattc gcccatggtt acgtgcgggg gagaatatga cctatgcgtt ttctaaagat
     1081 aatggtttgc aggctgctgc cgcagaatct agcgcatatt cttggactta tagagcctct
     1141 ccttgggttc ctgtacgtga tacacatggt aattatgcgg gttcaaagat aacaggtact
     1201 ggtaatttcc agaatcctgt ggcgattcaa gaaagaaaca aagataatta ttggacgaac
     1261 agtcgtatct tcggtaactt gtgggctgag gcggatttgt ttaaaggctt gacattccgt
     1321 acgaactttg gtctagatta tacgaataat tattcttatc gtatggataa gaaaaatcta
     1381 gagttctctg aaagccctgg taccaataat ctagaggaga tatctggctt caattttcgt
     1441 tgggtttgga cgaatacttt gacttatagc actgtcttta aggatgttca taagttgaac
     1501 gttttgttgg gtacagaggc tattcgtgac ggtataggac gtaagatgac gggacagcgt
     1561 ttcggttatc taatggaaga caacatgaat acatgggtat tgaatatggg agagaacgat
     1621 gcgcgtcgta gggctgaatc tgaatataag ggagagtttg ctctattcgg aatgtttgca
     1681 cgtgtggatt attcttttgc agacaaatac ttaattacgg gtatcgtgcg tcgtgatggt
     1741 gtatctcgtt tcgctaaagc gaatcgttat ggtgtgttcc cctccgtatc tttaggatgg
     1801 cgtatttctg aggagtcatt tatggaaaac acaaaggatt ggttggatga cttgaagttg
     1861 cgtgtagggt atggacaaac aggtaactcc gagatgagtc gtaagactaa ctatgcgttt
     1921 gagtacgcaa caaaatcgac aaacacgaat tatgacctgg gtgcttctaa ctctggatca
     1981 atggttggat tccgtttgga taaatatggt aatgaggata cgaaatggga agctacagag
     2041 atgacaaatg ttggtcttga tgccagtttt ttgaatggga agtttggatt aggttttgag
     2101 tggtactaca agaagacttc ggatatgtta atcgaggcgg cttattctgg attggcaggt
     2161 agcgagatag gcaagccata tttaaattat ggtgatatga agaataccgg ttgggatctg
     2221 acatttaatt atagagattc taaaggtgat tggggctggg atatcggcgt aaatgcttcc
     2281 gcttataaga atgaggtttt aaagctgtct aatacggacg atttctttat cggcaaagcc
     2341 ggtgctcgtt ttgagggtga acatgttact cgtacaacga aaggacaacc tatatcttct
     2401 ttctttggct ataatataat tggtttctat gagtctgctg atgatgttaa gaactcacca
     2461 ctgccttatg gtataagcag taaagaagag ttgaaaccag agcagatggt tggtaagttc
     2521 aagttcgagg atcgcaatgg cgatggtaaa gttaatggtg aagatcgtac gttcatcggt
     2581 agtcctcatc cagacttgat cttgagttta aatgcttccg ctacatggaa gaactgggat
     2641 ttcacgatgt tttggtattc tacgattgga aatgacatat ttaataacac aaagtacttt
     2701 acggatttcc cattgtttgg gggaaaccgt tctactcgta tgagagattt gtcgtggagg
     2761 ccaggtgcgg ataactcaaa ggcgatatta ccaatccttg actcaaagga ctcttggagt
     2821 ggtgcagttc ctagttcata ttacgtagag gatggctcgt tcttgagatt gaagaatgtg
     2881 gtattgggct ataccttccc gaaatctttg ttgcaaaaag ccactatctc taatttacgt
     2941 gtatatatac aagcagagaa cttgttgacg attagtggat atagcggttt ggatccagag
     3001 tttacgaatg ctgatgtagg cgaaggcaat ggagcagatt tgagacgtgg tattgatatg
     3061 ggtggttggc cgactacttt gagattgttg tttggggtga atttcgcttt ctgataaaaa
     3121 gtgaaacata tgaaaactag aataaaatat agaattatga aacaaaaata tatagcttta
     3181 ttagcttgtg catctttgtt gactttaggg gcttgtggag aagacttcct atataaagct
     3241 ccgcaaggtg cgattgataa agaggcgttg acgaatgcta atggtgtgga cttgctggta
     3301 acgaatgctt acgctaactt gacggagaat ggttggggag cttccgtttt caactggaca
     3361 tttggtggaa tgtacggtgg cgatgctaac aaaggatctg acggtaatga ccagtctatc
     3421 ttgaatacga tggaaatgta caatatgctt ccttccaatg gatacctaaa tgagaaatgg
     3481 gaatgggtgt ataaaggagc gaaacgtgtg aataatacat tgcagatcat tccggcggtt
     3541 acagatatgc ccgagaacgt taaaaatact cgtgttggtg agttgaaatt tcttcgtgcc
     3601 ttattttatt ttgaaggtat caaggtgttt ggtcctatga ttccgtgggt ggatgagaca
     3661 attgaagaaa acaatccttt ggtgcataat gacaaggaca tttatcaaaa tgtgcttaca
     3721 gatatagatg atgcgatctc taaactcccg gaaacccaag atatggtggg acgtgtaaat
     3781 atctgggcgg ctaaggcttt gaaagcgaag attttaatgc agaaagggga tatggcttct
     3841 gctaaaccta ttttgaaaga ggttattgag agtggtaaga cttctaatgg attagcctat
     3901 ggcctagaga atgatatgaa cgcaaatttt gattctttta gagataatgg taaagaatct
     3961 atctttgcta ttcaattctc tgtggatgct aatgataatg gtaattcagg gatgtctttg
     4021 tgctatcctc atggtggctc tggtaatccc ggaggctgtt gtggatttta tcagccgtct
     4081 agtgagttgg ctaactcttt caaggttgat gcgaatggcc tgccattatt ggataattcg
     4141 tatcgtgcgg gtaagcctgt ttcttatcgt aacagtagta caaatccaga ggatcctatt
     4201 gctttgaata atgatgagat tgcggtggat cctcgtttgg atttcgctat cggacgtttt
     4261 ggtattcctt ataaggattg gggtacccct aagaatggat gggtacgtga tgctgcaaac
     4321 ggtggtattt atttgccgaa gaaacatgta tattcaaagg cggaagaaga tgcgggcttg
     4381 gccagtggag ggttcagcgg aggttgggct ccgggttctg cgatgaattt gcaatatttg
     4441 agcttgcgtg attgtatttt gatgtatgca gagtgtttgg ctaacgatgg tcagttggca
     4501 gaagctatgt ctcaagtgaa caaaatccgt gttcgtgcag gtttggacgt gaatattatc
     4561 aagaaagatg gtaaaccagc cgctaattat aaaatcgctg agtatccctc gtctcacgct
     4621 gctttctctg ataagaatac ctgtatcaag gctgttcgta tggaacgtaa gcttgagtta
     4681 gcgatggagg gacaacgttg gtttgacttg caacgttggg gtggtgatta tatggctaag
     4741 actcttaagg aatatgtaga ctttgagaag ggttatttgg ctaaattctc tacggcttct
     4801 tatttgccag cggctaaggt aatgttccct attcctgatc agcaaatttc gaccatgggt
     4861 aacgacgaga gcggtcagcc gtacttggta cagccagctc cttggaaata attttgcttg
     4921 gttcaaagag cataatgatt aggttatgtt ctttgaagga tgttatttta tgtttaatat
     4981 tttaattgtt aagttatgag aaaaatatta ttggttattt ttgcttgtgc gtcaatgcaa
     5041 ttagggttcg ctgaggtaga gaatgataag gatgtcataa ttgaagacgt gaccgagatg
     5101 tctgtgaatg cagttaatgt agtgtatgag gttgacggac ctacatcgta cgccttaaat
     5161 ggctccactt caggagtggg gagtagttac agtatagccc ctcttcctcc tgctaatgct
     5221 actttctctt ggaaacttca agggggtggt agaggataca tctatccaaa tcagtataac
     5281 tgcggtatta atttgtatga tgccggatct tatcgtttat cttgtataat aacgattaat
     5341 ggcgttaaaa cagaatctgc tacttatatt acagtgacac cgtgatgatt ttttagtgtc
     5401 tgaatttaaa gggggtgtgt catttttgac acaccccctt tctgttgttc agctccagta
     5461 cttcaagagg taccctgcgc accccgctat aaggagggtg tagccggaga tacccagcca
     5521 gtccgccccg gggggcggtg gggaggaggg gtgccgtcgt ggcggaagag cgtcagcgag
     5581 gcgccgatcg ccgctagcgt cacctccgtc tcccgcatga ggagggagag gagggctagc
     5641 aggagaagga gcagcgccgg tagcgtctgt cgtttcggga acagggggat gctgcgggaa
     5701 gatgacccgg aggagcgccg tgaggcaacg gaggatgagt tcaaggtatt tcattttagt
     5761 tgacagttga tgataggggc ggcatctgcc cgccctttgg attaacgatt gatagttgcg
     5821 agctgatttt tcggcaaagc tggacgatca gcttacgata ggcttcccgg ttgtcgccgt
     5881 tcacctcgct gatgtagggg ctgtaggcga tctccttggc gaaggccgta gggttggcgc
     5941 tcatgtcggc cgcccgggga taggccgagc gaagcaggcg gcagtaatcc atgaacgagc
     6001 acttatcgtc cgggtagatc cggaaacgta gcgagcgggg cgacagctcc gtccaccggc
     6061 cggtccacca tacgttgggc aacccgtagg ccgtgatgcc gaaaaagtta tgatactccc
     6121 ggcagagcgt actctcgccc caacccgtct cgatggccgc ctgtgccaag atcaccaccg
     6181 gatcgatccg gaacgcccgc ccggcctccc cagccagcgg agcgtattca cgtataaaaa
     6241 cagaaatctc cataccactt aattttcaat tttcaattct caattttcaa ttccctaaat
     6301 ctcgtccggg ctctcggaat cgcccccgcc acctcccggg gtcacctccc cgttcgagta
     6361 ctcggtgtac tcgcggagct tggccgtcag cttaagcgag gcgctggaga gattgcccgt
     6421 ggcacgggca cggaggcgta cgccgatgat attgccttgc gtggagaaat cctccggcgt
     6481 gacggccccc ttcgagcgga tgcccacgct gaagatgccg aggtcgtcta tcttcacgtt
     6541 cttgccgtcc atcagcagct ccttgataca atttaccatg tccttcagca tgccgtggat
     6601 ggcgccggtg gagaaggggg tgttgtgggt ggacatgtgc tcggccaagg cggcgatgtc
     6661 taccgtctcc tcgcatacgg cacgggcgta ccacttgttg aaggttgtct cgttcttctc
     6721 gttcttgttt tgatacttct tgtagcggat cataatgtgt tgttttttaa tgttgataca
     6781 aagatacggc agggcatggg ggctttgtcg ctttgggtga cttagggtga tttcgggtga
     6841 attatttctc cggaaaatga tggatatatg ccggagattc actatcttta ggatatggaa
     6901 acgacattca agatacgagc gtacgggcgg atggagctgg ccgaggtcta cctgcccgac
     6961 ctgcatcccc gctcggccca ccgcaagctg caacattgga taacgatcta tcccggcctg
     7021 cccggtcgcc tccgctcgct gggttatcac gagggcgagc gggtctattc gcccgccatg
     7081 gtgcgggcca tcatcgagtc gctcggcgag ccgtgagagc cggatggtat ccgggtggaa
     7141 tagggtcgct aagtcaatgg aaagcgagac ggattccatt gacttagcga ccgtatctca
     7201 ttggttttcc ggtcatgttt cttaatcccg acgaatatcg gtaccggggt tagggcgcaa
     7261 aaggcgcatc tttacgtgcc tatataaaac ttttcttgta aatatatttt ttcatcacac
     7321 tgctatagtg tgatatatat ttatcttttt gtaaaatgtt tttccagaca ctgttttttg
     7381 cgccttttgc gccctgctca ttttagaaag tctgttttta ttccggctta tcttcttgac
     7441 ccttaaagat atcattctcc ttttgggctc tatcctcttc ctcttgccta gggcgcaaaa
     7501 aattggcttt tacctgttcc gaggtgatct cggcgacctc aaacagtagt tttcctctag
     7561 ttttcgtgag cttaaaacca tgttttttca gcaccttgct caacgtaact atattagaac
     7621 gtgtcggcgt gatacgtgta aatacactta gtttcgtcat aatatcgctc gccgtaagat
     7681 actgtggcgt gtcgaaacgc tccggtttgc ggaaataggt gaagaataat tcctcctcgg
     7741 ggcttcgctg gcggaaggtc tcgttgttct cgttgatctt ccggatgtct tcgccggaga
     7801 accagtattt ctcgccccgg cggaagaggg cgagagcttg ggcgtagatg tcggcgtgtc
     7861 gcacgggcga ctggtaatcg atccgtgtgg cctcgaagca gaggaagcgg cgagactcgt
     7921 tatcgtccgg cagcgattgc aagtcgttca ccgtggcggc gaaggaggcg tggcgtatct
     7981 gcgtctcggc atagtgtccg tacgggcggc gcaggtagat gaccccggtg gaggtgagcg
     8041 ccttgaggcg gttcagatcg gcgtagctct ggccggacat ctcgtcgatg acgatcaaga
     8101 ggcagtccac catcatctgc gggaaaccct tgctatacgg attgacattg cccgtgaaaa
     8161 gatagtcccg cagctcgggc ggcacgaggt tccgcagcca cgaggtcttg cccagcccct
     8221 gcccgccggc cagcagcagg atggtatggt tttccacgcc tagctccatg gagccggcca
     8281 ccccggcgat aagccagcgc ttgaggcaac cccgccagaa ggcgggccgg gtggtgtcca
     8341 cggtatcggc cagctgcccg atccagtccg tcaccccgtc ccacggggcc agcccctcga
     8401 aatacgagcg gaaagggtgg aacgtctcgc tgaagtccga catcagtatg gcccggatgt
     8461 cgttatgcga gcagtagtgg ccgtccttca ggagactccg ccaaagcgag ttcacccagt
     8521 agtcggtcac cggcttgaag accggctttt ggccgttccg ctttttcttc gtggctacct
     8581 ccacgtaccc cctcacgccg ttcttgcggg tgaggaaacg ctcggatata taggcctcca
     8641 cggcgaccac gtccagcggg cccccgccct ttttccggga ggtggcggcg ctcgtctcgg
     8701 cggcgtgctc ctccacgtgg ctgtaggcgc tctcgatggc ggcgaggcgc tcctccgccg
     8761 gcaagtcggc gaaggcggta gcggcgtaag cctccatctc ggcccgcttc acgcccagcc
     8821 ggttcgcccg tgcggccatg acgaagatga agttattgcg gttgccctcg gcgtaggcgc
     8881 ctttccgctc ggcggtccgg cgtgccttct ccagtggcga ggccaccttc ctttccttcg
     8941 ccccgggagc cgtctcgcta acctcctcct tccaagtaag gggtaacggg gcgaggccct
     9001 ccggtagctc gccggtaccc tccagccaag ggcggtaggc aggcgagagg tatagggcgg
     9061 gatcgtccga tacgaagcaa agccgcccga tgtcgctgcc cgaggtatcc agctccacgc
     9121 cgagccgggc ggcgtaccaa cggctcatgg cctcgtagac cctccggtga ttgcccggcg
     9181 tggcggtctc gtccgtggcg gcgtaggcga tgagtttcgc cccgtcgccg ctgggactgc
     9241 ggaaatacgc cacggtgtag ggcgcttccg tggcgagcgg ggtgatacgc tccagctccc
     9301 gttcccctac gtggtcgatg tcgagtacca ccaattggtt atagcgggtg atgtgagggt
     9361 cgaggcgttt cccggagtag gtggcctgtg gggtgaaagc gggcagtttt ttctttagtt
     9421 tggcggccag ttccttatcg cccgacgcta gcgcctcccg cgtctcgtcg atgaactgct
     9481 tgtacgttcc tctttggatg ttttccagta cgcccgctag cgaggcgtct cccttgtatc
     9541 gtccgaaaag ggcgaataat gatgtgttta tcatactatg tttttaagtg ataaaaaaag
     9601 agccagtgtc tctggcttga tggcgctaag gtagggaggc gctttgggac gcctcccaag
     9661 ttttaacttt tgttgtgaaa aacgggaagc ttgttattca tgcgctttcc cgtattcctc
     9721 ctgcgccgtc gagaggatgc tccggaagct ccttggctcc gggcagccgt tggggtgtat
     9781 ctcgaacacc tcgtccagcg cccgtatcat ggcttcccgg ttcgtctgcc cgttcacccg
     9841 gaaacgttgg tcatcgagga tgggcagcgt cagccgcacg aagtctttca cggagcccgt
     9901 gtagatgatc ttctcccgtt taaccagatc ctcctccggc tggtagtctt taaacaactt
     9961 atgcgcccct ttcgcgtctt ttttcaagtc cacccatgcc ttttgggcat tttccaaact
    10021 atccagcagc tttctcacgc ttgtttccgc ttcccggaaa ctgatttttt ttcatatatg
    10081 attaattgtt aaagttaaaa acgtcgcaaa ggtatattat ccacgtgata attcctcgga
    10141 agttgttggt ttgtcggata tatatgctta catttggcat gaaactttaa atctggatct
    10201 tatgagaaag cttctggggt ttttatgcgt atgcgcgttg gctatcgtta cggctagggc
    10261 acaagatgcg gtggatgact atgtctcttc cgccgccggc caatccgtga tctaccatgg
    10321 gaaggagcaa ttaaaatatc ccacctcgat aagaaatcac ccctatttga agagcgagaa
    10381 atacgtaccc ggggatctta gcttcgaagg cattctctac aaggacgtga aaatgcgctt
    10441 agacctgtac aagaatgagt tattactgtt ctctccggac aatcgctata atatcgtctt
    10501 gccgagcgat cgggtagact acgctgagtt tcatgggtac catatcttct acaggtatcc
    10561 ggatgagcgg tcgggcaacc tgccggaagg ctattaccta cggttgtatg aagggaagtg
    10621 taccgtgctg gggaaatggt cttgtatatt atctaagacg ataaaagata tgaagctcga
    10681 tgattccttc gatcagtccg taaaatacta catccggaag gagggcgttt actataccgt
    10741 gaggagcaag ggctccgtgt tgaaggtcct caagtccaag aaaaaagagc tggcccggta
    10801 tatcaagcgg cgaaagctgg atttcaagca cgctcccgag gaagccatcg tagccgtggt
    10861 gagacagtat gaacagttaa acgagatccc atgagaaaga gcctatatat cggtatggta
    10921 atgtgcctgc tgtccggctg gacggcgagg gcgcagcgga cggtcgatct ggatttccgg
    10981 caagtaacct tgaatgtcgt gttcaacgct atcgagcggc agaccggaca gcccgtctac
    11041 cggcaaccct tggagacgga ctccatggtc gttagcgtac acagtgagaa ggaagagccc
    11101 ttggtggcgt tgcggcgtgc gttggagggg actcccttcc aagtatcctc gtatggcggc
    11161 gccttctttg tattgagaga taacaccttg atgacctccc tgcccgagaa cttcttcctg
    11221 cgggagaagc ggagagaggg cgatggcgac gaggaaggct ccggtatctc cctgatggcg
    11281 ggccggaagc agcagaaggc tacctcggag aacaaggtct acgagatcgg cgacgcctcg
    11341 ggcaaggcgg cggaccgggt cacggtgacc ggtaatatca gcgatttcaa gaccggcgag
    11401 ccgatggtgg gcgtggccgt gttcgtgaag gacccgatga tcggggctac taccgacgct
    11461 tacggctatt atacgctgcg cctccctccc ggacgacacg agctgtacat acaaggcatg
    11521 ggcatgaagg acacccggcg gcagatcatg ctccattccg acggcaagct ggatatcgag
    11581 ctggaggaac aggtctacac cttgaaggag gtcacgatct cctccgagaa gatcgccaac
    11641 gtgcggaata cgacgatggg agtggaacgc ttgaaggtga aggatataaa gaatatcccg
    11701 atggcgttcg gggaggtgga tatcatgaag gtagtcatgt cgcttcccgg cgtgaaggcg
    11761 gtgggcgagg cctctagcgg ctttaacgtg aggggcgggg cgacggacca gaacttgatc
    11821 ctcttcaacg acggcacggt ctataacccg acccacctgt tcggcttctt ctccgtcttc
    11881 aaccccgacg tggtgaagga catggagctg tacaagagca gcatccccgc caagtatggc
    11941 ggacgtatct cctcggtact cgacatcaac agccgggagg gtaacaaaaa ggagttcaag
    12001 ggatcggcga gcatcggctt gctgaccagc cgccttacct tggaggggcc tctcttctcc
    12061 gagaagacct cctttatcgt gggcggacgt accacttact cggactggat cttgaagaaa
    12121 ctccccgaga agagcggcta taaggatggc aacgccggtt tttacgacct gaacgccacg
    12181 attaaccata agttcgacga gcggaacaac ctctatctga atggctacta cagccacgac
    12241 cgtttccgct ttaacgcgga tgagcggtat gcctacgaga acgccaacgc ctcggtgaaa
    12301 tggaggcata tcttctcgga tcgtttcacg ggggtcctca ccgctggcta cgaccattat
    12361 ggctacaata cccgtaatac ggataacccg gtgaacgctt attccctcgc tttccgtatc
    12421 gaccagatgt acgggaagat ggacttcacg cattacctga gcgataagca tacgctggat
    12481 ttcggtgcca gctcgctgtt ttacgacttg gagccgggga aataccttcc ctatggaggg
    12541 gagtcgttgg tgaaggagga ccggatggag aaggagaaag cggtggagtc cgctatctat
    12601 gtgggcgatc gttgggatat cacctcccaa ctctccttga acgtgggggt ccgttattcc
    12661 atgtttaacg tattggggcc ccgtacctat aatctctatg ccgacgacca actgccttcc
    12721 ttggctaccg tgacgggtac ggtggataag accggggcgt tcaagactta ccacgggccg
    12781 gagttccggg tatccgcccg ttatgccttt accgaggact tctccgtgaa ggccggcttt
    12841 aatacgatgc gccagaatat ccataagcta tccaatacga cgatcatgtc gcccacggat
    12901 acgtggaagc tgagcgacgc taacatcaag ccgcagacgg gtatgcaagt ggccgccggg
    12961 ctataccgga atttcttgaa caatacgatc gaggtctcct tggagggata ttacaagacg
    13021 atgaaggatt acctagatta ccggaacggc gccgagctgc tgatgaacca ccacatcgag
    13081 acggacgtgc tgaggaccga ggggcgtgcc tatggcgtgg agctgatggt gaagaaaacg
    13141 caagggaagt tgaacggctg ggtaagctat acctactctc gcacgcaact gcggcagaac
    13201 gacccgatga tcgtgaatcc cgtgaacaag ggggattggt acgccgccga cttcgataag
    13261 ccgcacgacc tgaagttcgt gggcaactat aagttcacgc atcgtttcag cttctcgctg
    13321 aattgcgact atagcacggg acggccgatc accttgccgg tctccaaata tcattacggg
    13381 ggcggtgagt ttgtctatta ttccgaccgt aatcaatacc gcatcccgga ctttttccgg
    13441 atggacgcct cgttcaacat cgagccgagc caccacctga cgttgctcac gcatagcacg
    13501 atctctttcg gagtctataa cctgacgggg cgaaagaacg cctactcggt gtattatata
    13561 tcggagaacg ggaaattaaa gggatataag atggcgatat tcggggtgcc tatcccgttt
    13621 gtctcttata atattaaatt ttagggggga gttgagatga ggaaagaagc gaagataaaa
    13681 gattctataa aaggctttca ttggtggctg ggggctttgc tgttgttatt gtccgcctgt
    13741 gtcacggatt acgagccgaa gggtttggag caggtacggg atttgttggt cgtggatggt
    13801 atcatcacga atggcgagac tacgataaag ctccggagaa gcgtgggcct gaccgacgat
    13861 ttcacggagg atgagttcgt gaataacgcc aaggtggtgg tggagcgtga ggatggagct
    13921 gttttcactt gcgctaattc ttccgggaag ggagagtata aggtggatat gggagagctg
    13981 gacccgggta gccggtaccg gctacatatc tcgctggatg ggctggagta tgagtcggac
    14041 tatctgggac cggagataac gcctccgatc gactctctct ccttgctgaa gaaggggccg
    14101 ggagaggagg tccgtctctg tgtgtctacg cataatgccc cggatcgatc ctcttatttc
    14161 cgctggatgt ataaggagaa ttgggaggtg aaggcggaga tcttcatggc tgccgagaaa
    14221 atgggtaata cggtcgtaat atatgattta cttacatcga ataattggta ttattgctgg
    14281 gggaaggaca gctcgaaggt gatctcccta ggcagttccg ataggctgac gcagaacgtg
    14341 atcgctaaca aaagtatcgc ctcgtatcat cccagcgatc gccgtttctc gatgttgtat
    14401 catgcggagg tggaacaata tgcgttgcac cgggaggctt acgactacta ttttaatttg
    14461 cagaagaaca tagaggagtc tggtagcttg tttgccccta ttccttccga gatgaaaggg
    14521 aatatccgct gcgtgacgga cccggaggtt ccggtgatcg gtttcgtgga agtagcgaca
    14581 gtgactcgcc tcaagcgttt ctttccggag atagagaagg tatatgaggc cgaggttacg
    14641 ggctgcgcaa gcacgatcgt acagggatcg gaatatgata ataatccgga ttacggatat
    14701 gtttcctata atccgatgaa tgcggcgagt aatacgtatg cgctgaaacg ttgtatggat
    14761 tgcggccgtt ttggttcgaa acagaagccc tcttggtggc ctaccagtca tttataattt
    14821 agttgctatg aagaagtcta tgataaaaca atgtatcttg tcgctcctct gcctcttatg
    14881 ggcggggcaa acggttctcg caggggaatt gcgagagcgg gtttacctgc aaacggataa
    14941 gcaattttat ctgtcgggcg agcttgtatg gatgaaattc attgccacgg atttggacca
    15001 acggttgtcc gacgtgagca aggtcgggta tgtggagctt ctggatagcg cctcggcggt
    15061 cgtgcaagcc cgactcgtgc tggagaaggg ggtagggaat ggttgcctgc aattgccttc
    15121 taccttgccg accggaaact accggctggt tgcctatacc cgttatatgc ggaacgaggg
    15181 ggaggaggtc ttctttgaga agccgctgac ggtggtgaac accttcgtga cgaatgaggc
    15241 cctgctgacg gatactttat tgcccactta ctcttttacg aggcgagagg gcccggtttc
    15301 cgtatcaccg gaccgtatga cctatgatac ccgttcaggg ggggagatcc ggataaacgg
    15361 cctgcccccg gatctacaga ctctatcggt ctctatcgcc gggatcgact tgtataaacc
    15421 ttccgcccgg agcggtatcg ttgattggaa acaaagcatg cctactacgg ggtcatcgcc
    15481 tgccgatcat aaattcttgg cggaatacga ggggccgatc ctgacgggga aagtgatcga
    15541 tctgtccacg ggcgaacctt cgtctaaaga ggcggtgagg cctttattgg gcttttccgg
    15601 gggggagatc cgccttttcg gggggcaact gggcgctgcc ggggaggtga ctttctttac
    15661 gaaacatata tctgggacgc acgagatcgt gacggtggct ttatcccctt cctcctctcg
    15721 ctaccgggtg gacatcgaat ctccttacgc tacgcatccg gagaaggagc ttcctgcctt
    15781 gagattgaat cccgcttggc aagatgagtt ggtgaagcgg agcgtggggc tacaggtgtt
    15841 gcatgcttac cggtctgatt ccttggttcg ggaaaaagcg gagaagcctt ggttccagtg
    15901 gcaaccggat tggagttatc ttttggatga gtacacccgt ttcacgacga tggaggaagt
    15961 cgtgatcgag tttatccccg gcctccgctt ccgtaagatg gatggggttc gccggttggc
    16021 ggtcctgacc gaggagcgga tcgggtatac gatcggtaac tcattggttt tattggatgg
    16081 tatccccatc accgatcacg agatcatttt taagtacgat cccctaaaaa tccggaagat
    16141 cgatgtgtat aaaggtaagt acgtattcgg tgggcagata ttcgacggta tcgcctcctt
    16201 ctcctcttat gagcataatt acccgggtct ggtagtcgat aactccaccc agttctttga
    16261 ttatgagggc acgcaagccc agcgcatctt ctatatgccc gcttaccgga cagaggccga
    16321 gaagcgatct ccnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16381 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnaagatgag
    16441 aagtttcgct agtgacaaca attccggcgt gcatccccgg gtaatggatg cgatcatcaa
    16501 ggcaaatgat aatcatgcgg ttggatatgg tgatgatcct tggacagagg ccgctacgag
    16561 taagatacaa gaagtgttcg gcaaggatgc ttctcctttt ttcgtgttta acgggacggg
    16621 ggcgaactcc gtggccctgc aagccgtaac ccgtccgttt aatagcatcc tgtgcgccga
    16681 gaccgcccat atcaacgtag acgaatgtgg agcccccgca cggatgaccg gttgcgccat
    16741 cgtcacgatc cctacgacgg acggtaagct gacaccggaa ttgatccgtc cccatctgaa
    16801 gaacttcggg gtttgccacc attcgcaacc caaggccgtt tatatctccc aagtatcgga
    16861 attaggtacg atctatacga tagaggaagt gaaagcgatc gccgatctct tacattcgta
    16921 cgatatgtat ctgcatatgg acggagcccg cttggcgaac gcctgcgctt acctgaattg
    16981 cacgatgcgc caagtgaccg tagacgcagg cgtggatatc ttgagcttcg gaggcacgaa
    17041 aaacggtatg atgatgggag aggccgtggt ctcgttccgc ccggagatca cggagaacct
    17101 gcgattttac cgaaagcaat ccgctcagct agcctcgaag ctacgttatc tctccgccca
    17161 gttcatccct tatctggaaa ataacctctg gttggagaac gccatgaaag cgaatatcag
    17221 tgccgccaag ctagcggacg tgctacgaca atacccggag attcatttta cgcagaagat
    17281 cgagtccaac cagctcttct tcacgatccc tgccgaggcg ttgaggaagt tgcaagataa
    17341 atatttcttc tatatgtgga acgaggagat caacgaggcc cgtctcgtta cctcttggga
    17401 tacttccggc gaggatatcg ctgagttcga gcagtcattg aaagagatat tcggttaagg
    17461 tatagatata aaatgaatat aaacattaga tcgaatccta tgaggaaatg gtttatttgg
    17521 gcgatcgtta tgatcggatg tttgcccata aataaggcat tggcacagca aagcggcgat
    17581 gccgagcgga atacgttgcg tatcatgagc tataatatcc gcaacggaag gggcatggat
    17641 gaggtgacgg acctcgggcg tatagcggag gctatacgta aggtagcccc cgatgtagtc
    17701 gccgtacagg aggtagatag cgtgaccgga agaagcggcg ggatcgacgt gctccggaca
    17761 ctgggagaac gcaccctgat gttccctacc tacgccccgg ccatcgactt tgatggcggt
    17821 aaatacggag taggtatgct gagcaaggag aagccggtga gctaccgcta tatcgccctt
    17881 cccggacggg aggaggaacg ggtcttgcta tgggtcgagt ttgagagata tatcttctgc
    17941 tgcacgcacc tttccttgac gccggaagac cggatgctct ccttgccgat ccttcggcgg
    18001 gaagccgctt ccgcgcataa acccctgttt atcgccgggg attggaacgc tacggcgcat
    18061 tcccccttta tcacggaaat cagcaaggat ttccagttgt tgagcaatcc taaacaggct
    18121 acattcccgg ctttcacgcc ggatagctgt ttggactata tagcgggtta tgtaaagaat
    18181 ggacagccct ttacccgttt gtccgcatgg gttcccgaag aggcggtggc atcggatcat
    18241 cgcccggtcg taacggaggt tcgtctgaag gctaagccgg aagagatctt ttatgcggcg
    18301 ccctatctcc aaaatcctac ggagggcggc ataacggtga tgtggcagac ccatgtccct
    18361 acgtatagtt gggtagaata cggtacggac acgctgaacc tgaaaaaggc ccgtaccatt
    18421 gtggacggtc aagtgatatg caacggcttg cataataaga tccggctgac ggacctacga
    18481 ccggggcaaa cctattacta ccgggtatgc tcgcaggaaa tcatgcttta ccaagcctat
    18541 aagaaagagt ttggcgagac ggcggtatcc ccgttctaca ctttcaaggt cccttccgca
    18601 tcccaaaagg atttcacggc cttgatcttt aacgacctgc ataagcagat cccgaccttg
    18661 gaggctttat acgagcaagt gcgtgatatc ccttatgatt tcgtggtatt taacggggat
    18721 tgtatagacg atcccgccaa tgagaaagaa gctttgtatc atttggctta tttatgcggg
    18781 aaggtgggcg ccagtcatgt acccgctttc ttcctaagag gcaaccacga gatacgcaac
    18841 gcttactcga tcggtttgcg tgccttgttt gactatgtgg gcgataagac gtatggggcg
    18901 ttcaactggg gagatacccg tttcgtcatg ctggattgcg gcgaggataa accggatagc
    18961 acatgggtgt attatggcct gaacgatttc accggtctcc ggaaagatca agtgagtttc
    19021 ctctcgaaag aattgaacgg caaggagttt aagcaagcct cgaagcgggt tttattgaac
    19081 catatcccta tctacggaaa cggggatgcc tatgagcctt gtccggagct ttggggaagc
    19141 ctgttggcga aagccccttt caacgtgaat atatccgccc atacgcatca atacgctttc
    19201 cacccgaaag gctcgttggg aaataacttc ccggtgatcg taggcggggg gtataagctc
    19261 gattcggcta cggtgatggt attgcggaag aaaggaaacg agatgagtct gcgagtgttg
    19321 agcgcaaaag gggagacctt attagacttg aaattataag agacagcatg gatacggatt
    19381 tgatttacgg gatcgatgac cgtccgcctt tgaaagagac gctttttgcc gccatccaac
    19441 atctgctggc tattttcgtt gcgatcataa cacctccctt gattatcgcc ggggcgctga
    19501 aactggatct ggagacgacc ggtttcttgg tttccatggc tctgtttgcc tccggggtat
    19561 c
//
LOCUS       DBMDTB010000078        19197 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_957_length_19197_cov_11.503299, whole genome shotgun sequence.
ACCESSION   DBMDTB010000078 DBMDTB010000000
VERSION     DBMDTB010000078.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 19197)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 19197)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19197
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_957_length_19197_cov_11.503299"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            6..146
                     /locus_tag="ACZPB4_12215"
     CDS             6..146
                     /locus_tag="ACZPB4_12215"
                     /inference="COORDINATES: protein motif:HMM:NF023021.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3244 domain-containing protein"
                     /protein_id="HIR1099010.1"
                     /translation="MKVYEDVVSSEAGGTYSFSLAGEANGQYQVVLLHRLGHLTGSFT
                     LE"
     gene            765..2663
                     /gene="dxs"
                     /locus_tag="ACZPB4_12220"
     CDS             765..2663
                     /gene="dxs"
                     /locus_tag="ACZPB4_12220"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HIR1099011.1"
                     /translation="MAESKVEHLLDSIHFPEDLRHLSQDKLEQVCADLRQYIIDVLSE
                     NPGHLGASLGTVELTVALHYVFNTPYDRIVWDVGHQAYGHKILTGRKDIFHTLRKFKG
                     ISGFPNPAESEYDAFIAGHASNSISAAMGMSVASALKKELDRHVIAVIGDGAMTGGLA
                     FEGLNNASANPNNLLIILNDNDMAIDHSVGGLSQYLVDITTSQAYNKMRYDVYRGLKK
                     IKLINNDRRENILRFNNSLKALLTQQHNLFEGFSIRYFGPVDGHDVNYLVKVLNDIKD
                     MQGPKLLHIKTKKGKGFKPAEESATEWHAPGKFNKETGQRIIVRKLDEPQLYQDVFGH
                     TLVELAENDERIVGVTPAMPSGCSMTYMMKAFPDRAFDVGIAEGHSVTFSAGLAKEGM
                     IPFCNVYSSFMQRAYDMVIHDVALQKLHMVICLDRAGLVGEDGATHHGVFDLAYLRPI
                     PNLVIASPLNELDLRNLMYTGYAAFDGPFVIRYPRGKGEMKDWRNEMQVLPIGKGKKL
                     RDGDDIAVLSIGPIGNEVIKAIEMVKEERVSIAHYDMIYLKPLDEELLHEIGQKYNRI
                     ITVENGVIKGGFGSAVLEFMADNGYTPHVKRIGVPDAFIEHGSIPELYQLCGMDAESI
                     AKQLKKEN"
     gene            2684..4021
                     /gene="trkA"
                     /locus_tag="ACZPB4_12225"
     CDS             2684..4021
                     /gene="trkA"
                     /locus_tag="ACZPB4_12225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009859895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HIR1099012.1"
                     /translation="MKIVIAGAGEVGTHLAKMLSQENQDIILMDPNEERLNFSKSSME
                     ILPMVGNPTSLRDLEEAGIKKADLFVSVTPEETTNVTACMLAHNLGAHRTLARINNYE
                     YLLPKNKELFEKLGINSMIYPEMLAAKEIVTAVRRPWTRQYWELFGGALILIGVKVRD
                     NSRLVNRVLAELLNEQKLYHIVAIKRKNETIIPRGTDRIESGDIVFFTTTRSHIEDVR
                     LLAGKKDPEVKKVIIMGGSRIAIRACQYLPNNIRVKVIEANKEKSHRIAEVVPSNVLI
                     INGDGRDTDLLMQEGIKDAQTFIALTENSSTNILACLAAKRLGVFKTIAKIENIDYIQ
                     LAESMDIGSVINKKLIAASHIYQFLLDADVSNVKCLTFANADVAELVARPDSKITKKQ
                     VKDLRLPKDMTLGGLIRDGEPMMIKGDTQIQAYDHVVVFCLDTAMRKLEDYFN"
     gene            4031..5485
                     /locus_tag="ACZPB4_12230"
     CDS             4031..5485
                     /locus_tag="ACZPB4_12230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HIR1099013.1"
                     /translation="MLNVRFIVKMLGVMFILETFFMLAATVVAFLYRGSDVYPLLISS
                     GILFGTGFLFYSMGFKANEHSAGRREGMLIVTLTWILFSLFGMLPFYIGGYIDNVTDA
                     FFETMSGFTTTGSTILTNIEALPKGILFWRSLTQWQGGIGMVVFTVALMPIFGGGASQ
                     MFDAETPGITHERFRPRITQVAKRLWGVYVFLTLFLVGLLWAGPMNLYDAVNHAFTAI
                     STGGYSTKNASIAYWNSSYIEYVITIFMFIGATNMTLVYFCFNGNVKKLIKDEEFRWF
                     FFFVLGAIIVVMVWILYLGFASDVENAFRKAAFQVVTLVSTCGFATDDYIPWGPFFWF
                     IALILMFICGCAGSTCGGLKMGRFVILTKNLSNEFKKQTHPHAVIPVRMNGHVVSGDI
                     VHRVLAFVFAYITLIVVSCLALSLDGMGFSEAIGAAVSAISNVGPGLGTLGPVSNFAD
                     VPTVSKWFLSFLMLTGRLEIFTVLTILVPGFWKQ"
     gene            5497..6384
                     /locus_tag="ACZPB4_12235"
     CDS             5497..6384
                     /locus_tag="ACZPB4_12235"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMP-30/gluconolactonase/LRE family protein"
                     /protein_id="HIR1099014.1"
                     /translation="MKSIQVIASLLCGILYCGISLNAQNVLKATGWMPEHTFTSGIEG
                     PAVDSEGNLYAVNYKKEGTIGIVRPDGSHGCFLVLPEGSTGNSIRFGKDGNMYVADYT
                     GHNILKVDMKSKKISVFAHEPKMNQPNDIVFASNGNIYASDPDWPNQKGQLWLITPDA
                     KVSLLETNMGTTNGIAVSEDGKRLYINESAQLKVWVYDICPDGTLRNKRLFHTFEGYG
                     MDGMKCDEKGNLYICRYDKGTIALLNPQGDLVEEIQLTGKQPSNLTFGGPDHRQCYVT
                     LQDRGCFETFKVPYPGKEW"
     gene            6449..7039
                     /gene="ruvA"
                     /locus_tag="ACZPB4_12240"
     CDS             6449..7039
                     /gene="ruvA"
                     /locus_tag="ACZPB4_12240"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HIR1099015.1"
                     /translation="MIEYIKGEIVELTPTRMILECGGIGYELNISLNTYSAFGNKTTG
                     KIYIYEVIREDAHLLFGFAEKIERELFLLLTSVSGVGPNTARMILSSLPPSELVQVIG
                     SKNEAALTAVKGIGLKTAQRILVDLKNKVKPMESMAGNLPEASVSNGAVTEEAVAALV
                     MLGFQKAASQKAVSAILKGSPTLAVEQVIKTALRML"
     gene            7090..14508
                     /gene="sov"
                     /locus_tag="ACZPB4_12245"
                     /gene_synonym="sprA"
     CDS             7090..14508
                     /gene="sov"
                     /locus_tag="ACZPB4_12245"
                     /gene_synonym="sprA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0071806 - protein transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="T9SS outer membrane translocon Sov/SprA"
                     /protein_id="HIR1099016.1"
                     /translation="MRKRILKYSIWIVVLLFGVGLYSLNADYLAYTSSLPELELLEAP
                     EDTIPPRYPVAKTTPEEYQDIVKQSPADLRDPENVKTTIEYDLKTNTYIVRTKLGDME
                     IGTPMSLTPAEYQDYSMQQSLRSYFRQKNEEEFQKATNKQFNLTDMQFNIGAAERIFG
                     PGGVRVRTQGSAEITMGLKTNKNNDPSLPERSRKRTFFNFDESVQLNVQASVGSKVNF
                     GMNYNTETSFDFDSKKLKLAYTGEEDEIIKSLEAGNVSMNTSNSLINGGAALFGMKAD
                     LQFGKLRVNALFAQQESESKTVSSKGGVQTKPFEIKVDEYDENRHFFLGHYFYDNYDK
                     FMESLPTVTSGIEISKIEVWVTNKRGNYDQSRNIVAFTDLGENESRNIGNTALVMPSG
                     TDRRPNNSANNLYTTLTTQFTGARKINMVNDALKGAMEGGRDFEKIESARLLESSEYT
                     LNKKLGYISLRTQLQADEVLGVAFSFIYNGKTYQVGEFSTDNKENTSDCIYVKLLKGI
                     TMSPDMMFWDLMMKNVYSLGAYSVQKEKFKLNVTYQSDSTGTYVNYLPEGNCANQILI
                     RVLGLDRLDTYDNPNPDGFFDFIDGYTIQAETGKIIFPCVQPFGSKLREKVGNAYASK
                     YVFQELYDSTLTVARQIAEKNKFLLSGEYKASSGSEIDLGATNVARGSVRVTAGGATL
                     TENVDYTVDYSLGRVTILNESIISSGTPVSVSLENQSTFNMQRKTMIGLDLNYQFNKD
                     FMVGATVMHMSEMPLTVKTTLGDESIKNTLWGLNTSYKAESQWLTNVFDKLPLLTLTK
                     PSQISFNAEFAHLIAGHYENQYTGGYSYLDDFESTQSGMDLLNPYAWNLASTPYEDSN
                     PKFPEAEKVNDIAYGKNRALLAWYTVDGIFTRKSSSSRPRHLTNDDLSNHYTRGVSYK
                     EIFPNKELGTNDNTTLPVLNLAFYPNERGPYNLDAENVNSDGTLGNPEKRWGGVMRKI
                     EPSDLESANYEYIEFWLLDPYLEDETAEGGDLYFNLGEISEDILKDERKFFENGMPVD
                     GDMSKVDTTVWGKVPRTQSTGYAFDAQNRELQDVGLNGLSTEEEQTFPTYADYLNKLR
                     AKLSGETISKMMDDPFSPFNDPAGDNYHYFRGDDYDAKELDILSRYKRYNGTEGNSQE
                     SDQRYATAGKSTPDVEDINGDNTLNETEKYFEYKISLRPKDLQVGVNNIVDERTPEVT
                     LMNGDKEKVKWYLFKIPIKDYEKRVGAIRDFKTVRFMRMYMTGFRKSTVLRFGTLELV
                     RGDWRTYTQDLSNPLVPPKSDGQIVVSSVNIEENGQRQPVNYVLPPGISRMFDSSQPQ
                     LLQQNEQALSMKITDLSPADARAVYKSTAYDLRRYKRLQMFAHAEAPIDESKTLSNGD
                     FSVFIRLGSDYKNNYYEYEVPLDLTPHSTILYNTNNSADQEKVWPLNNTLNFKLETLT
                     DLKLERNKLKRQGQGNISYQKVYSKNDPDNTRNKISIIGNPSLAEVKVIMIGVRNNTG
                     DIKSGEVWVNELRMTDFDEKGGWAANANLNVALSDLGTVNVSGRMETAGFGALDQSLA
                     ERRMDDYSQYSVATSIELGKLFPEKAKVSIPFYYAYSKETTTPEYDPLNEDIKLSDAL
                     DAVETQAEKDSIKSYSLDQTTIKSVSFNNVKVDIRSKNPMPYDPANFSLGYSYSQNSK
                     KNPETEYETTKDYRGNFAYNYTPYVKPFRPFEKLKKNNGYTKYIKQFGLNYVPSNISF
                     QTAMMRNYYEIKLRDLTSSTDGGNQLLSFSHNFLWDRAFSLRWDFTNNLSMTFTSGTN
                     ARIEEPNVQVNKKLNPDDYQVWKDSVKQSIRDLGTPLKYDQTFNVTWNMPLQFIPALD
                     WVNSSLTYNATYNWDRGANVASIELEQGNIIKNQRQFDWQGSFNLQSLYNKNKYLKKI
                     NQKFMASSRVSARQPEKKKKEVKLEKEIQLSPDSGTIVQHGMFTKKVRITARGADGKV
                     YSIKYKPINYAQVMILNKDTARLKLTIVPGPQPLEGTLTKVAEYSSRFLMMVRRVNIQ
                     YSLIDGMMLSGYAPEVGDMFGQRRTGTLAPGLGFAFGAVRRSFIDEADERGWLVKNEN
                     MTTPAMINSAKNLTIRANLEPIAGLKIDLNANRVDTRSTDIYYMQDGMPEQMGGSFTM
                     TTIALGSAFGGSGNANNGYSSKAFDKFIAHRSVIAQRLMDTYSGTVYPSSGFMAGHAL
                     AGKPYDPAVGGGVSLNSMEVLVPAFLAAYTGKDPNKVGLSAFPSVKSLLPNWRVTYDG
                     LIRIPVIRKYFKSMMLSHQYRCSYSVGAFSSFLDWVDAGQDGLGYIRDIQTGNPTPSS
                     PYDIAAVSITEGFSPLFGVDATLLNNITGKFELRKTRNLSLNISSYQLVEALSNEFVI
                     GVGYKLTEFNKVLKMKKTRDFSNDLTIRLDFSYRKMQSLIRKIEDQFTQATSGNIAKT
                     IQFSADYGLSRALTLRAFYDLQINEPIVSTSSYPTSNSNYGISLRFSLAQ"
     gene            14609..17323
                     /locus_tag="ACZPB4_12250"
     CDS             14609..17323
                     /locus_tag="ACZPB4_12250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HIR1099017.1"
                     /translation="MKNTYKLILFLLLITHASFGQDVKGYIKDAESKEALAGVNVFYK
                     DKGGTRGTVSDINGYYELKVTDGDAVLTFSYLGYETLSVPVKVDPGEFLTHDVSLRTN
                     SNMMDEVVVSVGRYEQKLSDITVSMELLKAKDITRQSPKDLTDVLKNISGVDVTDRQP
                     SVRGGTGWTYGVGSRCLILVDGMSVLTPGSGEINWNMIPMENVDQVEVLKGASSVLYG
                     SSALNGLIHVKTKRPGLDPVTQVNVQGGLYGKPRQDGTPLYGGLDLSHSRRIKNFDLT
                     VGANTFLDDGYRQDNYNRRVRVGGNLTYHDPRVQGLNYGVNVNYLYNDYTGFFIWRSP
                     EEPYIQSPLANMGRRENTFYIDPFLNYTNSEKGTTHRFKGRFFHRGSRIITHTTDKSL
                     FDITNNMGFDISSVPEIINIAQNWQTELLPTFLPYLPEVMNGKVSGLMGELGKLGNHF
                     FPTATSADYMDLISWVMGRTPLPDKNNVGAWLVDAMKPVEKKAPEATDHTYSYNLDYQ
                     FSKKFDHSQLTVGGTYERIHADSKVTGQHSSDNVATFLQYDHKFIDRLNVSVGVRLEY
                     YRVDDFYREAETKIFGAKVPVKPVFRGGLNYELGEYSFIRASFGQGYRYPSVTEKFIL
                     KDIGGVGAFPNAELKAEQGYNAELGFKQGYKFGNLKGFVDVAGFYTRYKDMIEFRFGL
                     FNNKTFDYIDGLSKLFNAFSSGDGLGIGAQFTNVGRAEIYGVDLSTSGVYEFNRDTRL
                     AYTLGYVYTNPIDMDVDSRNAEEEANDDLMAMRSKSNDSKYLKYRQKHSVKGVFDLEW
                     KQFNIGTNMSWKSKTLAVDYFMVDERTKAEPNLMDYMRSMLFGNLHDYWAENNKGYFV
                     MDMRVGMKVTKNIHVQGLVNNLLNKRYSARPMDVGAPRTFILQVGANF"
     gene            complement(17362..18060)
                     /locus_tag="ACZPB4_12255"
     CDS             complement(17362..18060)
                     /locus_tag="ACZPB4_12255"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metallopeptidase"
                     /protein_id="HIR1099018.1"
                     /translation="MEKNIQDKDLGVITLRTTPRATRYTLKISKGKITATMPPGGDEK
                     RMIAFIMENKARLVKALQKHPARPLLDERSELQATTFRLHIFRTERSNFYMRLEDGVL
                     HIACPNETRFEEEEVQSLLKSMLEKALRHEAKRLLPERITLLARQHGFMLTGVKINNS
                     KTHWGSCTMKKSINLSQSLMLLPWHLVDYVLLHELCHTIEMNHSERFWKLMDKVTNNQ
                     AIRLRSELKNYHML"
     gene            18167..>19197
                     /gene="gpmI"
                     /locus_tag="ACZPB4_12260"
     CDS             18167..>19197
                     /gene="gpmI"
                     /locus_tag="ACZPB4_12260"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004619 - phosphoglycerate mutase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-independent
                     phosphoglycerate mutase"
                     /protein_id="HIR1099019.1"
                     /translation="MSKKALLIICDGWGIGDKGKDDVIFNTPTPYWDELLKTYPASQL
                     QASGENVGLPDGQMGNSEVGHLNIGAGRIVYQDLVKINIACRENTIMENPEIKRAYGY
                     AKENNKQIHFMGLVSDGGVHSSLEHLLKLTDIAKEYGISKAYVHCFMDGRDTDPKSGK
                     GFIETLENHLKTTGGKIASIIGRYYAMDRDKRWERVKEAYDLLVEGKGKQAECMVKAM
                     EESYAEGVTDEFIKPIVHVENGKPVAVIEEGDVVIFFNYRNDRAKELTVVLTQQDMPE
                     AGMHTIPGLQYFCMTPYDASFKGVHILFDKENVNNTLGEFLANVGKTQLHIAETEKYA
                     HVTFFFNGGR"
BASE COUNT         5312 a         3544 c         4876 g         5465 t
ORIGIN      
        1 aaggagtgaa agtctatgaa gatgttgttt cttcagaggc aggtggaact tattctttct
       61 ctttagcggg agaagcaaat ggccagtatc aggttgtgtt gttacatcga ttgggacact
      121 tgaccggtag ctttaccttg gaataaaaaa ttaagaggtt ttgtaagaag aaagagctgt
      181 taagcttctc ggtaaaatag gaagcacagc tcttttttat ttggacaact gtaccatata
      241 cgagtcttta cttgaaaacg tatctatgta catgttttac cactaaacgt atcattaatc
      301 agccgggagc cattctgttt attgtatatt tcttgaaaat aggcttcatt gtagcctgct
      361 ttactatcca tagaaatagc gattagtatt aatagaaatt caaaatacta tggatactaa
      421 tcggagtttg gatagatacg attttattgt atgttgatta ttaggtgtat aggtaatagt
      481 ttggaaatat tagacttatt gtgcttttta agagatcaaa tttggtgtgg ttgggctatt
      541 tttatttcca aatggtgtta tttcatgact atattataac ttgaaaaatt catagttatg
      601 aaattcacaa ctcataacta tgttttgaaa aaaacataac tatgaaattt tataggattt
      661 agctgttaaa atcaatatgg atttccccct tgtctaagaa atgacaggac aatactatta
      721 tatatgccgt ttattctgta tttttgccag aaaaattagc agacatggct gaaagcaaag
      781 ttgaacacct attggatagc attcattttc cggaagactt gagacatttg tcacaggata
      841 agttggagca ggtatgtgcc gatttgcgtc aatatattat cgatgttttg tctgagaatc
      901 ccggccacct aggtgcaagc cttggtacgg tagagctgac agtcgccctt cattatgtat
      961 tcaatacccc ctatgaccgt attgtctggg atgtcgggca tcaagcttac ggacataaaa
     1021 tacttacagg aaggaaagat attttccata cgctccgtaa gtttaaagga attagtggct
     1081 tccctaatcc tgcggaaagt gagtatgacg cttttatcgc cggacacgcc tcaaattcaa
     1141 tctctgcggc gatgggtatg tcggtagcct cggccttgaa gaaggaactg gatcgccatg
     1201 tgatcgccgt gatcggggat ggcgctatga ccggaggact cgccttcgag gggttgaata
     1261 atgcgtctgc caaccctaat aatttgttga ttatcctgaa tgataacgat atggcgatag
     1321 atcatagcgt aggtggtctt agccagtatt tagtggatat aacgacgagt caagcctata
     1381 ataaaatgag atacgatgtg tatcgaggct taaagaagat caagctcatc aataacgatc
     1441 gcagggaaaa catcttacgt tttaacaata gccttaaagc attgcttacc cagcaacata
     1501 atttatttga aggcttcagc atccgttact ttggtccggt ggatgggcat gatgtaaatt
     1561 atctggtgaa ggtattgaat gatataaaag atatgcaagg ccctaagctg ttgcacatca
     1621 aaacgaaaaa aggaaaaggc tttaaacctg cggaagagtc cgctacggaa tggcatgctc
     1681 ccggaaagtt caataaggaa accggccagc gtattatcgt tcgtaaatta gatgagcctc
     1741 aattatatca agacgtattc ggtcatacat tggtagagct tgcggagaat gatgaacgta
     1801 ttgtaggcgt aactccggct atgccttccg gttgctcgat gacttatatg atgaaagcct
     1861 tcccggatcg tgcgtttgac gtgggaattg cggaaggaca ttccgtaact ttctctgctg
     1921 gattagctaa ggagggaatg atacctttct gcaacgtgta ttcctcgttt atgcagcgtg
     1981 cgtatgatat ggttatccat gatgtagctt tgcaaaaact acatatggtg atctgtctgg
     2041 atcgtgcggg attagtggga gaggatggag ctacacatca tggcgtgttt gatttagcat
     2101 atcttcgtcc gataccgaat ttggtaatcg cttccccatt gaatgagttg gatttacgga
     2161 atttgatgta tacaggctat gccgcttttg atggcccgtt cgtaatccgt taccctagag
     2221 gtaaggggga gatgaaagat tggcgtaacg agatgcaagt attgcctatt ggaaaaggaa
     2281 aaaagttgcg tgacggggat gatatcgccg tactttctat cggaccgatc ggaaacgagg
     2341 tgatcaaagc catcgagatg gtgaaagaag agagggtatc gatagcccat tacgatatga
     2401 tctacttgaa accgttggat gaggagctgt tgcatgagat cgggcagaaa tataaccgta
     2461 ttattacggt agagaatgga gtgataaaag gaggttttgg tagcgctgtc cttgagttta
     2521 tggcagacaa tggctatacg cctcatgtaa agcgtatcgg agtgccggat gcgtttatcg
     2581 agcatggttc tataccggaa ctgtatcaat tatgtggtat ggatgccgag agtatcgcga
     2641 aacagttgaa aaaggagaat tgattattgt caattaataa aatatgaaaa ttgtcatagc
     2701 cggtgcggga gaagtaggta cacatttagc gaaaatgtta tctcaagaga atcaggacat
     2761 cattttgatg gatccgaatg aggaacggct gaatttctca aaatctagca tggagattct
     2821 ccctatggtc gggaatccga cctcgcttag agatttggag gaggcgggga tcaagaaagc
     2881 ggacttgttc gtaagtgtta ctcccgagga gactaccaat gtaacggctt gtatgttggc
     2941 tcataatcta ggagcgcatc gtacgttggc ccgaatcaat aattacgaat atttattgcc
     3001 taaaaataaa gagctgttcg agaaactggg aatcaactcg atgatttacc ctgagatgtt
     3061 ggcggctaag gagatcgtga cagctgtacg ccgtccgtgg acacgccaat attgggagct
     3121 gtttggtgga gctttaattc tgataggtgt taaagttcgg gataattccc gtttggtgaa
     3181 ccgggtattg gccgaattgc taaatgagca gaagctatat catatcgtcg ctattaagcg
     3241 aaagaacgag acgataatcc cccgtggtac ggaccggata gagtctggtg acatcgtgtt
     3301 ctttacgacg acccgatctc atatagagga tgtgcgctta ctggccggga agaaagatcc
     3361 ggaagtaaag aaggttatta ttatgggagg aagccgtatc gctatccgtg cttgccaata
     3421 tttacctaat aacatccggg taaaagtaat tgaggctaat aaagagaaaa gtcatcgaat
     3481 cgctgaggta gtgcctagta atgtcttgat tataaacgga gacggccgtg atactgattt
     3541 gttgatgcaa gaaggcatca aggatgcgca gacttttata gctttgacgg aaaattccag
     3601 cacgaatata ttggcatgtc tggccgctaa gcgtttaggt gtgtttaaga caatcgctaa
     3661 gattgagaat atcgattata tccaattggc ggaaagtatg gacatcggtt cggttatcaa
     3721 caaaaagctg atagcggcca gccatatcta tcaatttctt ttggatgcgg atgtctctaa
     3781 cgtgaaatgt ttgacctttg cgaatgcgga tgtggcggag ttggtggctc gcccggattc
     3841 aaagattacc aagaaacaag tcaaggatct ccgtctgccg aaagatatga ctctcggtgg
     3901 gttgattcgt gacggtgaac ctatgatgat caagggtgat actcagatac aggcatacga
     3961 tcatgttgtc gtattctgct tggatacggc tatgcgtaag ctggaggact actttaacta
     4021 gttgatagtt atgttgaacg tacgttttat agtgaagatg ctaggggtga tgttcatcct
     4081 tgagactttt tttatgctgg ctgctaccgt cgtagccttc ctttatcggg ggagtgatgt
     4141 atatccgctt cttatttcaa gcggaatctt attcgggacc ggttttttgt tctactctat
     4201 gggctttaag gcgaatgaac actcggccgg ccggcgggaa ggaatgttga tcgtgacatt
     4261 gacatggatt ttattctctt tatttggaat gttaccattc tatataggag gatatataga
     4321 taatgtgacc gatgcctttt tcgagaccat gtccggattt acgactacag gctctactat
     4381 tttaacgaat atagaagcgt tgcctaaagg tatcttattc tggcggagtc ttacacagtg
     4441 gcagggaggt atcggtatgg tcgtattcac cgtggctttg atgcctattt tcgggggtgg
     4501 tgcctcgcag atgtttgatg ccgaaacgcc cggtataacc catgaacgtt ttcgtcctcg
     4561 tattacgcaa gtcgctaaac gcctgtgggg ggtgtatgtt tttctgacac tttttttagt
     4621 cggcctttta tgggctggtc cgatgaattt gtatgatgcg gtaaatcatg cgttcacggc
     4681 tatatctact ggtggatatt caaccaaaaa cgcaagtatc gcttattgga attcctctta
     4741 tatagagtat gtaataacta ttttcatgtt tatcggagct accaatatga cattggttta
     4801 tttctgtttt aatggaaatg tgaagaaatt gattaaagat gaggagtttc gctggttttt
     4861 cttttttgtt ttaggcgcta ttatcgttgt catggtgtgg atcttgtacc ttggattcgc
     4921 ctcggatgta gagaatgcgt tccgtaaggc ggctttccaa gtggtgacct tggtttctac
     4981 ctgtggattc gctacggatg actatattcc ttggggaccg tttttctggt ttatcgcatt
     5041 gatcttgatg tttatttgtg gatgcgccgg atctacttgc ggtggcttga agatgggacg
     5101 cttcgttatt ttaacgaaga atctctccaa tgaatttaag aaacagacac atccccatgc
     5161 ggtgattcca gtacgaatga acgggcatgt cgtatctggt gatatcgtac atcgtgtgtt
     5221 agcttttgtg ttcgcttata ttacgttaat cgtggtgagc tgtttggctt tatctttgga
     5281 tgggatggga ttttcggagg cgattggtgc cgctgtttct gctataagta acgtagggcc
     5341 cggcttggga acgcttggtc cggtaagtaa ttttgcggat gttcccacgg tgtcgaaatg
     5401 gtttctgtct tttttgatgt taacagggcg tctggagata tttacggtat taacgatatt
     5461 agtccccggt ttttggaaac agtaaaatta ttgaaaatga aaagtataca ggtcattgct
     5521 agtctgctgt gtggtattct gtattgtggg atttctttaa atgcccagaa tgtattgaaa
     5581 gcaacaggtt ggatgccaga gcacacattt acttccggaa tagaaggtcc ggctgtagat
     5641 agcgaaggaa atttatatgc cgtaaattat aagaaagaag ggacgatcgg tattgtacgc
     5701 ccagatggta gccatggctg ttttctcgtt ttgccggaag gatctaccgg gaatagtatc
     5761 cgcttcggga aagacggaaa tatgtacgtg gcggattata cagggcataa tatcttaaaa
     5821 gtggatatga aatctaagaa gatcagtgta ttcgctcatg agccaaagat gaatcaacca
     5881 aacgatattg tatttgcctc caatggaaat atctatgcga gtgacccgga ttggccgaat
     5941 caaaaaggcc aactttggtt gattaccccg gatgcgaaag tctccttatt ggagacgaat
     6001 atgggaacga ctaatggcat cgctgtgagt gaggatggta aacgcttgta cattaatgaa
     6061 tctgctcaat taaaagtctg ggtatatgat atatgcccgg atggtacttt aaggaataaa
     6121 cgtctatttc atacttttga ggggtacggt atggatggta tgaagtgtga cgagaaagga
     6181 aatctttata tttgccgtta tgataagggt actatagctt tgttaaatcc gcaaggagat
     6241 ttagttgaag agattcaatt gacaggaaag cagccgtcta acttaacatt tggaggacct
     6301 gatcatcgtc aatgttatgt gacattgcag gatcggggtt gttttgaaac ctttaaggtt
     6361 ccttatccgg gaaaagaatg gtaacccgat atacgttttt gattaatttt gcgttataat
     6421 aggtacggaa tattaaaaag atatatagat gatagaatat ataaagggtg aaatcgtgga
     6481 acttacacct acacgtatga ttttggagtg tggtggtata ggctacgagc tgaatatatc
     6541 cttgaataca tatagtgcgt ttgggaacaa gactaccgga aaaatatata tatatgaggt
     6601 aatccgggaa gatgctcatt tactatttgg ctttgccgag aaaatcgaaa gggagttgtt
     6661 ccttttgctt acttccgttt ctggagtggg accgaatacc gcacgcatga tcctttcttc
     6721 tctaccgcca tccgaattgg ttcaagtgat cggttcgaag aatgaggccg cattgactgc
     6781 cgtgaaaggg attggtttga agacggccca gcgtatcttg gtagatttga aaaataaggt
     6841 gaaacctatg gagagtatgg ccggaaactt gccggaggca tcagtctcta atggagcggt
     6901 aaccgaggag gccgtagccg cattggttat gttaggtttc cagaaagcgg cttcgcaaaa
     6961 agcggtatcc gctattttga aaggctcgcc cactttagct gtggaacaag taattaaaac
     7021 tgcgcttaga atgctttgat aattgacaat tgaggattaa cgattaacaa ttgacaatta
     7081 aatgagaaaa tgagaaaacg aatactgaaa tattccatat ggatcgttgt attattgttt
     7141 ggtgtcggct tgtattcgct gaatgctgat taccttgcgt atacatcatc tttgccggaa
     7201 ttggagttgc tggaagctcc ggaggatacg attcctcccc gttatccggt agctaaaact
     7261 acaccggagg aatatcaaga tatcgtgaaa caatcacctg ccgatttgcg tgatccggag
     7321 aatgtcaaga ctacgattga gtatgattta aagacgaata cgtatattgt ccgtacgaaa
     7381 ttaggcgata tggagattgg tacgccgatg agtttaaccc cagcggaata ccaagattat
     7441 tctatgcaac aatcacttcg ttcctatttc cgccaaaaga acgaggaaga attccaaaaa
     7501 gctacgaata aacagtttaa cttaaccgat atgcagttta atatcggtgc ggcggaacgt
     7561 attttcggcc ccggtggagt acgtgtaaga acacaaggtt cggccgagat cacgatggga
     7621 ttgaagacga ataagaataa tgatccttct cttccggagc gttcccgtaa acgtactttc
     7681 ttcaattttg acgagagtgt gcagttaaat gtacaagcct cggtgggtag caaggtgaat
     7741 ttcggaatga attacaatac cgagacctct tttgatttcg attccaagaa attgaagttg
     7801 gcgtatacgg gcgaggagga tgagattatc aaatcgttgg aagccggtaa cgtgagcatg
     7861 aataccagca actccttgat taatggaggt gcggctttat ttggtatgaa agcggattta
     7921 caatttggta agttgcgagt gaacgccttg tttgcccagc aggaatctga atccaagacg
     7981 gttagctcaa aagggggcgt gcagacgaag cccttcgaga tcaaggtgga tgaatacgac
     8041 gagaaccgtc acttcttctt gggccattat ttctatgata actacgataa gtttatggag
     8101 tctttgccta ccgtcacctc cggtatcgag atctctaaga tagaagtgtg ggtgaccaat
     8161 aaacgaggta attatgacca gtcccgcaat atcgtagctt tcactgattt gggagaaaat
     8221 gaatctcgta atatcggtaa tacagccttg gtaatgcctt ccggaacgga taggcgtccg
     8281 aataattccg caaacaattt atatacgact ttaaccactc aatttacggg tgcccgtaag
     8341 attaatatgg tgaatgatgc tttgaaaggt gccatggagg gaggacggga ttttgagaaa
     8401 atcgagagtg cccgtttgct agagtcgtct gagtatacat taaacaagaa attgggttat
     8461 atttctttga ggactcagtt acaggctgat gaggtattgg gtgtcgcttt tagttttatc
     8521 tataatggca agacctatca agtcggtgag ttctctacgg ataataaaga gaatacgagt
     8581 gactgtattt atgtgaagtt gctaaagggc atcacgatgt cgcctgatat gatgttctgg
     8641 gacttgatga tgaagaacgt atactcattg ggtgcttatt cggtgcagaa agagaagttt
     8701 aagttgaacg ttacctacca gagcgattct accggtacgt atgtaaacta tcttccggaa
     8761 ggtaattgtg cgaatcaaat cttgattcgg gtattagggc tggatcgctt ggatacctat
     8821 gacaatccga atccggatgg cttcttcgat tttattgacg gttatacgat acaggcggag
     8881 accggtaaga ttatattccc ttgtgtacaa cctttcggct cgaaattacg ggaaaaggta
     8941 ggtaatgcct atgccagtaa atatgtattc caagagttgt atgactcgac attaactgtt
     9001 gctcgccaga tcgccgagaa aaataaattc cttttaagtg gtgagtataa agcctcgtcg
     9061 ggttcggaga tcgacttggg agctactaac gtggcccgtg ggtctgtacg tgtcacggca
     9121 ggaggagcta cactgacaga gaatgtggat tatacggtag attacagttt aggacgtgtg
     9181 acgatcttga atgagagcat catatctagt ggaacacccg ttagcgtatc tctggagaac
     9241 cagtctactt ttaatatgca gcgaaagacg atgatcgggt tagacttgaa ttaccagttc
     9301 aataaggact tcatggtcgg tgccacggtt atgcatatgt cggaaatgcc tcttacggta
     9361 aaaaccactt tgggagatga gtctataaag aatactttat ggggcttgaa tacctcttat
     9421 aaagcagaga gccagtggtt gacaaacgta tttgataagt tacccttgtt gacattgacc
     9481 aaacctagcc aaatctcatt caatgcggaa ttcgctcatt taatagcggg acattatgag
     9541 aatcaatata cgggtggtta ctcttatttg gatgacttcg agtctacaca aagtggtatg
     9601 gatcttttga acccgtatgc ttggaacttg gcgagtaccc cctatgaaga ttcgaatcct
     9661 aaatttccgg aagcggagaa ggtgaacgat atcgcttatg gtaaaaacag agctttgttg
     9721 gcttggtata cggtagacgg aatcttcaca cgtaagagtt cctcttcccg ccctcgacat
     9781 cttacgaatg atgatttatc gaatcattac acccgtggag tcagttataa agagatcttc
     9841 ccgaataaag agttgggaac caatgataat acgactttgc ctgtattaaa cctcgctttt
     9901 tacccgaatg agcgtggtcc gtataaccta gatgcggaaa atgtaaactc ggacggtacg
     9961 ttgggtaatc cggaaaaacg ttggggcggt gtaatgcgta agatcgagcc tagcgatttg
    10021 gaatctgcca attatgaata tatcgaattc tggcttttag acccgtatct tgaggacgag
    10081 acagccgaag gtggtgacct atactttaac ttgggtgaga tttccgagga tattttgaaa
    10141 gatgagcgga aattctttga gaatggcatg cctgtggacg gtgatatgtc gaaagttgat
    10201 acgactgttt ggggtaaggt tcctcgcacg caaagtacgg gatatgcgtt tgatgcccaa
    10261 aatcgtgagt tgcaagatgt cggtttgaac ggtctttcta cggaggaaga gcagactttc
    10321 cctacgtatg cggattattt gaataaattg agggcgaaac tatccggtga gaccatctct
    10381 aagatgatgg atgatccatt ttctcctttt aacgatcctg ccggggataa ttatcattat
    10441 ttccgtgggg atgattacga tgctaaggag ttggatattt tatctcgcta taaacgatat
    10501 aacggtacag agggaaactc acaagaatcc gatcaaagat atgctacagc cggaaagagt
    10561 acaccggatg tggaagatat caatggcgat aatacgttga atgagacaga gaaatatttt
    10621 gagtacaaga tctctctccg tccaaaagat ttgcaggtcg gtgtaaataa catcgtcgat
    10681 gagcgtactc cggaagtaac cttgatgaat ggtgataagg agaaagtaaa atggtatcta
    10741 tttaagattc ctattaaaga ttatgagaag agggttggag cgatccggga tttcaagact
    10801 gtccgtttca tgcgtatgta tatgacagga ttccgtaagt ctacggttct gcgttttggt
    10861 accttggaac tggtccgtgg tgattggcgt acttatacgc aggatttgtc aaatcctctt
    10921 gttccgccaa agtctgatgg acagatagtc gtatcttctg tgaatataga ggagaacggg
    10981 cagcgtcagc cggtcaacta tgtgttgcct ccgggtatta gccgtatgtt cgattccagc
    11041 cagcctcagt tgcttcaaca gaacgagcag gcattgtcta tgaagataac ggatttatct
    11101 cctgcggatg cacgtgcggt ttataaatct accgcttatg accttcgccg gtataaacga
    11161 ttacaaatgt tcgctcatgc ggaagcgccg attgatgaga gcaagacttt gtcgaatggt
    11221 gatttctctg tatttattcg tttaggttct gactataaga ataattatta tgagtatgag
    11281 gtacctttgg atctgactcc ccatagtact attctttata atacgaacaa tagcgcggat
    11341 caagaaaaag tatggccttt aaataatacc ttgaatttta aattggagac gctgaccgac
    11401 ttgaagttgg agcgaaataa attgaaacgt caaggacagg gaaatataag ctaccaaaag
    11461 gtttattcga aaaatgatcc ggataatacg cgtaataaaa tcagtatcat cggtaaccct
    11521 agcttagcgg aggtgaaagt gatcatgatc ggcgtacgta ataatacggg tgatatcaag
    11581 agcggtgagg tctgggtaaa cgaacttcgt atgaccgatt tcgatgagaa aggtggttgg
    11641 gccgctaatg cgaatctgaa cgtcgcttta tccgatttgg gtacggtcaa tgtaagtgga
    11701 cgaatggaaa ccgccggctt tggtgcgttg gatcagtcgc tggccgaacg tcggatggat
    11761 gattattcgc aatatagtgt ggcgacctcg attgagttgg gtaagttgtt ccctgagaaa
    11821 gcaaaggtta gcataccttt ttactatgct tattcgaaag agactacaac tcctgagtat
    11881 gatccgttga atgaggatat taagctttcg gacgctttgg atgcggtaga gacccaagcc
    11941 gagaaagact ctatcaagag ttattctttg gaccagacca cgattaagag cgtctctttc
    12001 aataacgtaa aggtggatat ccgtagtaag aatccgatgc cgtatgatcc ggctaacttc
    12061 tcgttaggtt actcttatag ccagaacagt aagaagaatc cggagaccga atatgagaca
    12121 accaaggatt accggggtaa tttcgcttat aattatacgc cttacgtgaa accgttccga
    12181 cccttcgaga agctgaagaa gaataatgga tatacaaaat atatcaagca attcggactg
    12241 aattacgtcc cgtcgaatat tagtttccag acggcgatga tgcggaatta ctatgagatt
    12301 aagctaaggg atttgacaag ttctacggat ggaggtaacc agttgctctc attcagtcac
    12361 aatttcttgt gggaccgtgc cttcagtttg cgttgggact ttacgaataa tctgagcatg
    12421 acgtttactt ccggtacgaa tgcccgcatc gaggaaccga atgttcaagt gaataagaaa
    12481 ttgaatccgg atgattatca ggtatggaag gattccgtga agcaaagtat ccgtgatttg
    12541 ggtactcctt tgaaatatga ccaaacgttt aatgtcactt ggaatatgcc attgcaattc
    12601 ataccggcat tagactgggt aaatagttca ttgacttata atgccacgta caactgggat
    12661 cgtggagcca atgtcgctag tattgagttg gaacagggta atataataaa gaaccaacgt
    12721 caatttgact ggcagggtag tttcaatttg cagtcattgt acaataagaa taaatatctg
    12781 aagaagatca accagaaatt tatggcctct tcccgggtaa gcgctcgtca accggagaaa
    12841 aagaagaaag aggtgaaact agagaaagag atccaattga gcccggatag tggaacgatc
    12901 gtgcagcatg gaatgtttac gaagaaggtt cgtatcacgg cacgtggagc ggacgggaag
    12961 gtctattcaa ttaaatacaa gccgatcaat tacgcccaag tcatgatctt gaataaggat
    13021 acggcccgtt tgaagctgac aatcgtgccc ggtcctcagc ctttggaagg aaccttgacg
    13081 aaagtcgctg agtatagtag ccgtttcttg atgatggtac gtcgggtaaa catacaatat
    13141 tcgttgatag acggtatgat gttgagtggt tacgctccgg aggttggcga tatgttcgga
    13201 caacggcgta caggaacttt ggctccggga ctcggttttg cttttggagc ggtaagaagg
    13261 agctttatcg acgaggcgga cgagcggggc tggctggtaa agaatgagaa tatgacgact
    13321 cccgccatga tcaatagcgc gaagaatctt acgattcgtg cgaatctaga acctatagcc
    13381 ggcttgaaga ttgatttgaa cgcaaaccgg gtagataccc gtagtaccga tatctattat
    13441 atgcaagacg gtatgcccga gcagatggga ggtagcttca cgatgactac gattgccttg
    13501 gggagcgctt tcggcggcag cggaaacgct aataacggtt attcctcgaa agcgttcgat
    13561 aaatttatcg ctcatcgtag cgtgatcgcc cagcgtttga tggataccta ttccggtacg
    13621 gtttatccga gctccggttt tatggcgggg catgctttag cgggaaaacc ttatgatcca
    13681 gccgtagggg gaggcgtaag cctgaattcc atggaggtat tggtacctgc tttcttggcg
    13741 gcttatacgg gtaaggaccc gaataaggta ggcttgtcag ccttcccgtc tgttaagagc
    13801 ctgctaccga actggcgtgt tacgtatgat ggcttgatcc gtataccggt tatccgcaaa
    13861 tactttaaga gtatgatgtt aagtcatcaa tatcgttgtt cctatagcgt aggtgcgttt
    13921 tcctccttct tggattgggt agatgccggg caggatggtt tgggatatat ccgcgatatc
    13981 cagacaggta atcctacgcc gtcgtctcct tatgatatag cggccgtgag tatcacggaa
    14041 ggattcagcc cgttgtttgg tgtggacgct actttattga ataatataac aggtaaattt
    14101 gagttgcgca agactcgtaa cttaagcttg aatatttcct cttaccaatt ggtggaagcg
    14161 ctttccaacg aattcgtgat aggagtagga tataagttga ctgagtttaa caaggtgttg
    14221 aaaatgaaaa agacacgcga cttcagtaat gatcttacga tccgcttaga tttctcttac
    14281 cgtaaaatgc aatcgttgat ccgtaagatt gaggatcagt ttacgcaggc taccagcggg
    14341 aatatcgcca agaccatcca gttctccgcg gattacgggt taagtcgtgc cttgacattg
    14401 agagcgttct atgatttaca gatcaatgag ccgatcgtgt ccacatcttc ttacccgaca
    14461 tcgaactcga actatggtat tagtttacgg ttctccttag cgcaataaaa agagtatagt
    14521 ctatttacag gacttcttgg tctgttttta aatacctgtc tagcggtatg gaataaacct
    14581 ttatatttgt gcgaaatata atttggatat gaagaatact tacaaattga tattatttct
    14641 tctcttgata acccatgcct ctttcggcca agacgtgaaa gggtatatta aggatgcgga
    14701 gagcaaggaa gctttagccg gggtaaacgt tttttataag gacaaagggg gtacgagagg
    14761 aactgtgtct gatataaacg gttattatga gctgaaagtg acggatggcg acgctgtatt
    14821 gacttttagc tatctgggat atgaaacgtt gagcgttccc gtgaaagtag atccgggaga
    14881 gttcttgacg catgacgtat ccttgcgaac aaactcaaac atgatggacg aggtcgtcgt
    14941 gagcgtcggg cgttatgagc aaaagctaag cgatattacc gtctctatgg aattactgaa
    15001 agcgaaagat atcactcgtc agtctccgaa agatttaacg gacgtattga agaatatctc
    15061 cggtgtggac gtgacggacc ggcaaccttc cgtacgcggt ggtacgggat ggacctatgg
    15121 cgtgggtagc cgttgcttga ttctggtgga cggaatgtcg gtgctaactc cgggttccgg
    15181 cgagataaac tggaatatga tcccgatgga gaacgtcgat caagtagagg tactgaaagg
    15241 ggcctcttcc gtattatatg gctcttctgc cttgaatggt ttgattcacg tgaaaacgaa
    15301 acgccccgga ttggatccgg taacacaggt gaacgtacaa ggaggtctgt atggaaagcc
    15361 acgccaagac gggacgcctt tatatggagg cttggatctc tctcattccc gtaggatcaa
    15421 gaattttgat ttgacagtgg gggctaatac attcttggac gacgggtatc ggcaggataa
    15481 ttacaaccgc cgtgtccggg tcggtgggaa tcttacgtat cacgatcccc gggtacaagg
    15541 gttgaactat ggcgtgaacg tgaattattt gtataacgat tataccggtt tctttatctg
    15601 gcgttctccg gaggagccct atattcaatc tccgctggcg aatatgggac gccgtgagaa
    15661 tacattttat atagatccct tcttgaatta tacgaattcg gaaaaaggga cgactcatcg
    15721 tttcaagggg cgtttcttcc atcggggaag ccgtatcatc acgcatacta cggataagtc
    15781 tctttttgac ataacgaata atatgggttt tgatatctca tccgtcccgg agattatcaa
    15841 tatagcgcaa aactggcaaa ccgagttgtt gccgaccttc ttaccgtatt taccggaggt
    15901 gatgaacggg aaggtgagcg gattgatggg tgaattgggc aagctgggaa atcatttttt
    15961 cccgacagct acctcagcgg attatatgga cttgatttct tgggtgatgg gacgtactcc
    16021 gctacccgat aagaataacg taggggcttg gttggtagat gccatgaagc cggtggagaa
    16081 aaaggcgccg gaggctacgg atcatactta ttcttataat ctggattacc aattcagcaa
    16141 gaagttcgat cattcacaac tcacggttgg aggtacttat gagcggattc atgcggattc
    16201 gaaagtgacc gggcagcata gtagcgataa tgtggctacc ttcctgcaat atgatcataa
    16261 atttatcgat cgtttgaacg tctcggtcgg tgttcgtctg gagtattacc gggtcgatga
    16321 tttctaccgg gaagcggaga cgaagatttt cggggcgaag gttccggtaa aacctgtttt
    16381 ccgtggaggc ttgaattatg agttgggtga gtatagtttt atccgggctt ctttcggaca
    16441 gggataccgt tatccatccg ttacggagaa gtttatcctg aaggatatcg gaggtgtggg
    16501 agctttcccg aacgctgaat tgaaagcgga gcaaggttat aatgccgaac ttggtttcaa
    16561 gcaaggttat aagttcggca atttgaaggg ctttgtcgat gtggccggct tttatacccg
    16621 ttacaaggat atgatcgagt tccgtttcgg cctgtttaat aataagacct tcgattatat
    16681 cgatgggctt tccaagttgt ttaatgcgtt ctctagcggc gacggcttag gaatcggcgc
    16741 tcagttcacg aacgtaggcc gggcggagat ttatggggta gatttgtcta cctcgggtgt
    16801 gtatgagttt aaccgtgata ctcgtctggc atatactttg gggtatgttt atacgaatcc
    16861 gatcgatatg gacgtggatt cacggaacgc ggaggaggaa gcgaatgatg acttaatggc
    16921 gatgcgttcg aaatcgaatg acagcaagta tttaaaatat cgccagaaac attccgtaaa
    16981 gggggtattt gatctggaat ggaaacagtt taatatcgga acgaatatgt catggaaaag
    17041 caagacattg gcggtcgatt attttatggt tgatgagcgt acgaaagcgg agcctaacct
    17101 gatggattat atgcgctcga tgctattcgg aaacttacat gattattggg cagagaacaa
    17161 taaaggatat ttcgtcatgg atatgcgtgt cgggatgaaa gtgacgaaga atatccatgt
    17221 acaaggactg gtgaacaacc tcttaaacaa gcgctatagc gcccgcccga tggatgtcgg
    17281 cgcaccccgg actttcattc tgcaagtagg agccaatttc taacaaatta cctagttgta
    17341 gagacggagc acgctccgtc tctacaacat gtgatagttt ttcaattcgc ttcgtaaacg
    17401 aatcgcttga ttgttcgtca ccttatccat tagtttccag aatctttcgc tatggttcat
    17461 ctctatcgta tggcaaagct catgcaataa tacataatcc accaaatgcc aaggaagaag
    17521 cattaatgat tgcgagaggt taatgctctt cttcattgta caacttcccc aatgcgtttt
    17581 gctattattg attttcaccc cggtcaacat aaatccatgt tgcctagcca atagcgtgat
    17641 acgttccggc aacaaccgtt tcgcctcgtg gcggagcgcc ttctccagca tggatttcaa
    17701 taaggattgc acctcttcct cctcgaaacg agtctcattc ggacaagcga tatgcagtac
    17761 cccatcctcc aatctcatgt agaaattact tcgctcggtg cggaagatat gcaagcggaa
    17821 tgtcgtagcc tgtaactccg atctttcgtc gagcaggggc cgggccggat gcttctggag
    17881 cgcttttacc agccgggcct tgttctccat gataaaagcg atcatacgtt tctcgtctcc
    17941 cccgggtggc atcgtggcgg ttatctttcc ttttgatatc ttgagcgtgt atcgagtggc
    18001 ccggggagtg gtacggagcg ttatgactcc caaatccttg tcttgtatat tcttttccat
    18061 tcctgccaca aaagtaatac attgagagaa acaataatac gatggaattg attatcttcg
    18121 cgatcgtaaa ggttaaaaac ataatcaata taataaatta gcaatcatga gcaaaaaagc
    18181 acttttaatt atctgtgatg gttggggaat tggtgacaaa ggtaaagacg acgtgatctt
    18241 taacacgccg actccatatt gggacgagtt attgaaaact tatccagcct cacagttaca
    18301 ggcttctggc gagaacgttg gtttgcctga cggacaaatg ggtaactctg aggtgggcca
    18361 cttgaacatc ggtgctggcc gtatcgttta ccaagatttg gtgaagatca acatcgcttg
    18421 ccgcgagaat acgatcatgg agaacccgga gatcaaacgt gcttatggct atgcgaaaga
    18481 gaataataag cagatccact tcatgggctt ggtttccgat ggtggtgtac atagctcttt
    18541 ggagcatctt ttgaagttga cggatatcgc caaggaatac ggaatcagca aggcttatgt
    18601 acattgcttc atggatggcc gtgatacgga cccgaagagt ggtaaaggct ttatcgagac
    18661 gttggagaat catctgaaga ctaccggcgg taagatcgct tctatcatcg gacgttatta
    18721 cgctatggac cgtgacaaac gttgggaacg cgtgaaagag gcttacgact tattggttga
    18781 aggtaagggt aagcaagccg agtgcatggt aaaagcgatg gaagagtcgt acgctgaggg
    18841 tgtgacagac gagttcatca agccgatcgt tcacgttgag aacggaaagc cggttgctgt
    18901 tatcgaggaa ggcgatgtcg tgatcttctt caactaccgt aacgaccgtg cgaaagagct
    18961 tacggttgta ttgactcagc aagatatgcc ggaggccggt atgcatacga tcccgggctt
    19021 gcaatatttc tgtatgactc cgtatgacgc tagcttcaag ggtgttcata tcttgttcga
    19081 caaagagaac gtaaataata cgctgggtga gttcttggca aacgtaggta agactcagtt
    19141 gcatatcgcc gagacagaga aatacgctca cgtgactttc ttcttcaacg gtggccg
//
LOCUS       DBMDTB010000079        19190 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_958_length_19190_cov_12.918068, whole genome shotgun sequence.
ACCESSION   DBMDTB010000079 DBMDTB010000000
VERSION     DBMDTB010000079.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 19190)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 19190)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19190
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_958_length_19190_cov_12.918068"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..626)
                     /locus_tag="ACZPB4_12265"
     CDS             complement(<1..626)
                     /locus_tag="ACZPB4_12265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolB family protein"
                     /protein_id="HIR1099020.1"
                     /translation="MKRFLNSVLCMCIAVFCTHAQKKNVTSVLEVMDITTGQRSVVKE
                     FPFLIEAPNWTPDGNWLVYNSGGKLYKLSPESPGEPQLINSDYATRCNNDHVISADGK
                     QIAISNGTKEDGRSRIYTLPFEGGVPRLITPLGPSYLHGWSPDGKQLAYCAERNGNFD
                     VYVIPALGGEEKRLTTAEGLDDGPEYSPCGQYIWFNSVRTGLMQVWRM"
     gene            complement(722..1825)
                     /gene="ychF"
                     /locus_tag="ACZPB4_12270"
     CDS             complement(722..1825)
                     /gene="ychF"
                     /locus_tag="ACZPB4_12270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007661265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HIR1099021.1"
                     /translation="MALQCGIVGLPNVGKSTLFNCLSNAKAQSANFPFCTIEPNVGVI
                     TVPDERLNKLAEIEHPQRVIPTTVEIVDIAGLVKGASKGEGLGNKFLANIRETDAILH
                     VLRCFDDDNIVHVDGRVDPVRDKEIIDYELQIKDLETIDSRIAKVQKQAQTGGDKQAK
                     IAYEVLCKYKEALEQGKSARTVSFDTKDEERIAHDLFLLTDKPVMYVCNVDEASAVNG
                     NKYVDAVREAVKDEDAQILVVAAKIESEIAEFDTYEERQMFLQEIGLEESGVSRLIKS
                     AYKLLNLQTFLTAGSEECRAWTFHKGWKAPQCAGVIHTDFEKGFIRAEVIKYEDYIAY
                     GSEAAVKEAGKMSIEGKEYVVQDGDIMHFRFNV"
     gene            complement(2032..3180)
                     /gene="araJ"
                     /locus_tag="ACZPB4_12275"
     CDS             complement(2032..3180)
                     /gene="araJ"
                     /locus_tag="ACZPB4_12275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter AraJ"
                     /protein_id="HIR1099022.1"
                     /translation="MKKSLIALAFGTLGLGIAEFVMMGILPDIAKDLHISIATAGHLI
                     SAYALGVCVGAPMLIIARRYPLKHILLVLVGIMMIGNLCAALASNYWVLMIARFISGL
                     PHGAYFGVGSIVAEKLADKGRGSEAVSIMIAGMTIANLFGVPLGTALSTMLSWRLTFL
                     LVGCWGIAILYYIWRWVPMVENLPDTGFKGQFRFLKTQAPWLILGATMLGNGGVFCWY
                     SYISPLLTQVSGFSAESLTVLMVLAGFGMVAGNLISGRLSDKYMPGRVAAIAQGMICV
                     ALLLVFFLAQISWLNVLLMCLCTAGLFAVSSPQQVLLIRYSKGGEMLGAASVQVAFNL
                     GNAIGAYCGGLPLEVGLGYKYPALIGSGFAFIGFLLLTFFYRKYERTT"
     gene            complement(3391..6156)
                     /gene="polA"
                     /locus_tag="ACZPB4_12280"
     CDS             complement(3391..6156)
                     /gene="polA"
                     /locus_tag="ACZPB4_12280"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HIR1099023.1"
                     /translation="MKLFLIDAYALIYRSYYAFIKNPRINSKGVNTSAIFGFINSLED
                     VLKRENPTHIAVAFDPKGPTFRHEAFEQYKAQREETPEVIRQSVPIIKEIIEAYNIPI
                     LEVPRYEADDVIGTVSKQAEKEGFEVYMMTPDKDYGQLVSEHIFMYRPKFGGDYEIMG
                     VPEVLNKYGLTSTEQVIDLLGLMGDASDNIPGCPGVGEKTAQKLLTEFGSIENLLANT
                     DKLKGAQKKKVEENAEQIHFSKFLATIKTDVPIEFDAARCVREKPNEERLTEIYTELE
                     FRTFINKLSSEPVKAAPKGPVQGDLFAIFTPESTEEPKKSILTDLKSTPHNYYLTDTE
                     EKQADLARFLLGQEFFAFDTETDGIDPLKAGLVGMSFAVKENEAWYVPVPANSVEAAK
                     VVERFSPALQNPKSLKIGQNIKFDILVLRKYNVKVAGPLFDTMIAHYLLNPELRHGMD
                     YLAETYLKYQTVHIEELIGPKGKNQLSMRNVPVEQIAEYAAEDADVTLKLKNYFAPEL
                     KKEGLESLFTTIEMPLIYVLVEMEATGVTLDTVALKQSSGELTASMNKLEQEVYELAG
                     TEFNINSTKQVGEILFDRLKLDEKAKKTKTGGYSTSEDVLEKLRSKHPIIGKLLEYRG
                     LKKLLSTYIDALPELINPQTGKIHTSFNQAVTSTGRLSSTNPNLQNIPVRDDLGREIR
                     KAFIPDNADCLFFSADYSQIELRIMAHLSGDPHMIEAFQSGADIHAATAAKIYGIPVE
                     KVTSDMRRKAKTANFGIIYGISVFGLAERLGIPRSESKELIDGYFSTYPRIKEYMEES
                     IKVAKEKGYVETIFKRKRFLPDINSHNAVVRGYAERNAINAPIQGSAADIIKLAMVRI
                     YERFEEEGLKSKMILQVHDELNFNIYKEEAEEVKKIVLEEMENVMKLQVPLIADCGEG
                     ENWLEAH"
     gene            6258..7232
                     /locus_tag="ACZPB4_12285"
     CDS             6258..7232
                     /locus_tag="ACZPB4_12285"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HIR1099024.1"
                     /translation="MDERRKIEEPVSAEFERFNKDFEASLRSETTRLQSAIDVILNST
                     GKHVRPLLVLLTAKVCGQVTDNTINSAVLLELLHTATLIHDDVIDETKQRRGVPSLNA
                     IFDNRISVLVGDYVLSTALIRSIQTGDLRIVGIISNLGRDLSEGEIKQLETAEESILD
                     ENCYLQVIKKKTATLLSACTEIGAISSGASAEVIALCREFGEYLGYCFQIKDDIFDYF
                     KEANIGKPTGNDIREGKVTLPLLYALRQGREEEAARYLDMILRKDFAAENVDSLIEFA
                     KANGGIEYAEARMKEYHDKAVDVLLRLPESEARTSLIQLADYIMTRSK"
     gene            complement(7424..8362)
                     /gene="deoC"
                     /locus_tag="ACZPB4_12290"
     CDS             complement(7424..8362)
                     /gene="deoC"
                     /locus_tag="ACZPB4_12290"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004139 - deoxyribose-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HIR1099025.1"
                     /translation="MAHHHDCECGHDHHHEHEHESNSVQIDRYHEAFNKFEPALPDTQ
                     TTETVNALLEKHFQENFTPEVLKTIHGCIDLTSLTSLDTKENIWKMVDTVNDFEGTRP
                     DVPNVAAICVYPLFVETVKQALTAQEVKIASVAGGFPSSQTFTEVKIAETAMAVMQGA
                     DEIDVVMNLGYFMEDNFEELTEELQEIKESCRHAHLKVILETGALVTTENIQKASILA
                     MYSGADFIKTSTGKGYPGATFEAAYTMCKAIKTYHSITGNKVGIKISGGVRTAEDAVR
                     YYTIVKEILGDEWLNKDLFRIGASSLVGDIEKRLGK"
     gene            complement(8367..8699)
                     /locus_tag="ACZPB4_12295"
     CDS             complement(8367..8699)
                     /locus_tag="ACZPB4_12295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HIR1099026.1"
                     /translation="MADITLQQAQQMVDAWIKTYGVRYFNELTNMTILTEEVGELARI
                     MARTYGEQSFKESDKHRDLGDEMADVLWVLLCLANQTGVDLTAAFEKNLQKKTDRDKE
                     RHINNQKL"
     gene            complement(8702..9154)
                     /gene="dtd"
                     /locus_tag="ACZPB4_12300"
     CDS             complement(8702..9154)
                     /gene="dtd"
                     /locus_tag="ACZPB4_12300"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005843922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - peptidyl-tRNA hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HIR1099027.1"
                     /translation="MRTVTQRVQHASVTIDGQLKSKIGKGLLVLVGIEDKDTQEDIEW
                     LAKKITNLRIFDDENGVMNRSVIEAGGEIMVVSQFTLHASTKKGNRPSYLKASKPDIA
                     IPMYKAFCEEVGLQLGKPVQTGTFGADMKIELLNDGPVTIIIDSQNKE"
     gene            complement(9171..11006)
                     /gene="uvrC"
                     /locus_tag="ACZPB4_12305"
     CDS             complement(9171..11006)
                     /gene="uvrC"
                     /locus_tag="ACZPB4_12305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HIR1099028.1"
                     /translation="MIADKDEHIKTILSVIPEKPGCYQYFDENGTIIYVGKAKNLKRR
                     VSSYFNKVHDSNKTRVLVKQIRDIKYIVVDTEEDALLLENNLIKQYRPRYNVLLKDDK
                     TYPSIVVKNEYFPRVFQTRNIVRDGSQYYGPYPSLFTAKVMLQMLKELYPLRTCKYPL
                     TPESIAQGRYKVCLEYHIKRCKGPCEGLQSLEEYQQNISEIKEILRGNISQISKHLYE
                     EMQSLAAELKFEEAQKIKEKYEVIENYRSKSTVVTPMLHNIDVFTIIENDHSAYVNFM
                     HIGNGAIVQAYTFEYKKRLDESKEELLSLGIIEMRNRFKSTAREIIVPFKLDMQLENV
                     TFTIPQRGDKKKLLDLSEMNVKQFKVDRLKQAEKLNPEQRNTRILKEIQEALHLEKLP
                     AHIECFDNSNIQGSDAVAACVVFKMGKPSKQEYRKYNIKTVVGPDDYASMKEVVRRRY
                     GRAIEERSPLPDLIITDGGKGQMEVVRSVVEDELGLSIPIAGLAKDGKHRTSELLFGF
                     PPVTVGMRLDSPLFHLLTRIQDEVHRFAITFHKDKRSKTQTKSELDTIKGIGEKTKVL
                     LLRHFKSVKRIKEASFEELKSVIGEAKAKALQEGLDGKRTESEQK"
     gene            complement(11003..12640)
                     /gene="ade"
                     /locus_tag="ACZPB4_12310"
     CDS             complement(11003..12640)
                     /gene="ade"
                     /locus_tag="ACZPB4_12310"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000034 - adenine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006146 - adenine catabolic process
                     [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HIR1099029.1"
                     /translation="MNEAKTLVIRGNLVDIINRRTFGAEISILNGHIGKVTPTGQDEG
                     YYLLPGFIDAHVHIESSMVTPTAFIHAAVRHGSIGAVADPHEIANVMGTEGVEYMLDN
                     AKGIPFYTWFGVPSCVPATIMETSGAIIDADETARLLEREDLHFLAEMMNYPGVLNKD
                     PEVMRKIEAAKQAGKPIDGHYPLATGPKLKAYIESGISTDHETIYLEKGREKCELGMH
                     VLIREGSAAKNFDALHPLLKEYPEQIMFCTDDAHPSFLNKGHINRMVKKSLDLGYDLY
                     DVLRAASYNPAMHYKIPAGFLREGDSADFIQVNNLKDLTIQATYIQGTCVYDGEKCTL
                     PLQKPIHRNNFHTKPITLEKLAVKAKGEQMRVIVCEDSELITKEELYPVHTFDGFVES
                     DTERDILKLVILNRYQTAPPAITFIKGTGLKLGAIAQSISHDSHNIIAIGVTDFELMQ
                     AINVVIKAKGGIAVSCMDEVTLLSLPVAGLMSDESLEETSCRYEEIEEKIKRLKSPMD
                     SLQMTLSFMGLLAIPSLKLSNKGLFNSETFQFTSLFV"
     gene            complement(12685..14562)
                     /gene="mnmG"
                     /locus_tag="ACZPB4_12315"
     CDS             complement(12685..14562)
                     /gene="mnmG"
                     /locus_tag="ACZPB4_12315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008156150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HIR1099030.1"
                     /translation="MTFNYDVIVVGAGHAGCEAAAAAANLGSKTLLITMDMNKIAQMS
                     CNPAVGGIAKGQIVREIDALGGYMGIVTDQTAIQFRMLNRSKGPAMWSPRAQSDRARF
                     IDCWRGILENMPNLSIWQDMVQELIIEHGQVCGVRTGMNVVFRAGAVVLTNGTFLNGL
                     LHIGRTQIRGGRIAEPAATGLTEQLVSLGIQTDRMKTGTPVRIDGRSVHFDEMEEQPG
                     ENDFHKFSYMDTSHRKLKQLSCWTTFTNEACHDILREGLPDSPLYNGQIKSIGPRYCP
                     SIETKIVTFADKTQHQLFLEPEGEATQEYYLNGFSSSLPLDIQLRALQAIPAFRDVQI
                     YRPGYAIEYDFFDPTQLRHNLETKQIRNLFFAGQINGTTGYEEAGGQGLVAGINAHIN
                     CHGGQPFILGRDEAYIGVLIDDLVTKGVDEPYRMFTSRAEYRILLRQDDADMRLTEKS
                     HQMGLAKQDRYDLLREKKESRDAIIRFAETYSVKPQYINSGLEKLGTAPLSHGCKLFD
                     VVLRPQTTLENLADLVPALRAELDKVPASRKEEIIEAAEILIKYSGYIKREQIIADKI
                     NRLENIRIKGKFDYNSIQSLSTEARQKLTRIDPDTIAQASRIPGISPSDINILLVLLG
                     R"
     gene            14681..15829
                     /locus_tag="ACZPB4_12320"
     CDS             14681..15829
                     /locus_tag="ACZPB4_12320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009016522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HIR1099031.1"
                     /translation="MNSIQCRILVFLVLLTSCFSPVCGKDKKPRQAIEKLSIDGPYLL
                     KADDGSMRAISVDGKGRLLDKHYKSIPTTFSFEVFSDNGERLFPVTIHSVSRPKWKDV
                     QPEKTFVLSDPHANWSCFASLLKAGKVIDADYNWIFGANQLVIIGDVFDRGVDVLPIY
                     WLIYKLEKEAEDAGGKVTFLIGNHETMVLGNDLRYTKKKYTQLADTLGMTYPELWQKS
                     ELGHWLKTRNSIQVVGDNLFVHAGLSKEFLDRNYDIPTVNEIVSDGLFLTKKERNADK
                     GSDLSFMFATYGPIWYRGMVRSADKYHPLDRDDLRKILEKYNVNRIFVGHTIFDDITT
                     FYHYKVIAVNVDNQENKEKERGRGVMIEKDGSMFVVYDSGKQEPLLTE"
     gene            15975..16613
                     /locus_tag="ACZPB4_12325"
     CDS             15975..16613
                     /locus_tag="ACZPB4_12325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0015288 - porin activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="porin family protein"
                     /protein_id="HIR1099032.1"
                     /translation="MKKVVLLFILFVFSLSQADAQEFHFIPRIGLNLANTYPESFADM
                     RPGLNIGVAEEIRFSKLFALEPGVYYSMQGYQQENAKGETARLKADYLNIPVYAKFYL
                     YRGFHLFAGPQVGFNVRAKASNYIFVSAPTPVHQSEYDFSGDKKEEIRNCDFSVSMGL
                     GYTFDMGLVISANYNLGCTHFFKEPEYSFGGSNHFRGKDHNGVIQFNLGWRF"
     gene            complement(16586..16759)
                     /locus_tag="ACZPB4_12330"
     CDS             complement(16586..16759)
                     /locus_tag="ACZPB4_12330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099033.1"
                     /translation="MKTEDIPYDYTYCYATDEQCPKAVHCLCSHAARLNEEQAISLNS
                     RFTGDQKRHPRLN"
     gene            complement(16780..17586)
                     /locus_tag="ACZPB4_12335"
     CDS             complement(16780..17586)
                     /locus_tag="ACZPB4_12335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="KilA-N domain-containing protein"
                     /protein_id="HIR1099034.1"
                     /translation="MEKITVQNTSVMIISINKNDYISLTDIAKYKSDDPTAVIGNWMR
                     NRNTIEYLGIWESLYNPNFKPLEFEGFKKEAGLNAFTLSPQKWINTTAAIGIISKSGR
                     YGGTFAHKDIAFKFASWISVEFELYIVKEFQRLKEEEQKQIGWTAKRELSKINYHIHT
                     DAIKHNLIPIELTPQQVSFIYANEADILNVALFGTTAKQWREANPELKGNIRDYATIN
                     ELICLSNMESLNAVFIDEGLTQRERLIKLNQIAIQQMKILEAVESRLLLK"
     gene            complement(17640..18068)
                     /gene="ybeY"
                     /locus_tag="ACZPB4_12340"
     CDS             complement(17640..18068)
                     /gene="ybeY"
                     /locus_tag="ACZPB4_12340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009016521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HIR1099035.1"
                     /translation="MAIAYYAEDIQLPAIKKKAVSGWIKAVAETYGKKTGDISYIFCS
                     DEKILEVNRQYLQHDYYTDIITFDYTEGNKISGDLFISLDTVRTNAETFHTDYNEELH
                     RTIIHGILHLCGINDKGPGEREIMEENENRALAILPEECQ"
     gene            complement(18159..>19190)
                     /locus_tag="ACZPB4_12345"
     CDS             complement(18159..>19190)
                     /locus_tag="ACZPB4_12345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside recognition domain-containing
                     protein"
                     /protein_id="HIR1099036.1"
                     /translation="EKGGVIQAFARLAAPVFSKLFPDIPRDHPVTGSIFMNLSANLLG
                     LDNAATPMGLKAMQQLQELNPNKESASNSMVMFLCINASGLTLIPITIMMYRAQLGAA
                     NPSDVFLPIMLATFTSTLVAILAVCVRQKINILQRNLVLFFGGLGLFIGGLVWLFNSM
                     EQEQVSLYSTLFANTLLFTIICGFIISGMRKKINVYDAFIEGAKEGFQTAITIIPYLV
                     AILVGIGVFRASGAMDFIIQGVRFGIASIGLNTDFVEALPTMLMKPLSGSGARGMMLD
                     AMNTYGADSFVGRLSSIVQGSCDTTFYVVALYYGSVGIRNTRYTVQCALLADLAGAIA
                     AIAMAYLFF"
BASE COUNT         4628 a         4366 c         4464 g         5732 t
ORIGIN      
        1 ttcatgcgcc agacttgcat aagcccggta cgtacggagt tgaaccagat atattgtccg
       61 caaggtgagt attcggggcc atcgtccaaa ccttcggctg tcgtaagacg tttttcttct
      121 ccgcctaggg caggaatgac gtaaacatca aaattaccgt ttctctcggc gcaataagcg
      181 agttgttttc cgtcggggct ccacccgtgt aggtagctag gaccgagtgg ggtaatcaat
      241 cggggaacac ctccttcgaa aggcagggta tagatacgcg accggccatc ttctttcgtt
      301 ccgttactga tcgctatttg cttcccatcc gcggagatca catggtcgtt gttgcaacgg
      361 gtcgcgtagt cgctattgat taattgcggc tctcccggag attccggaga gagcttatat
      421 aattttcctc cactattata tacaagccaa ttaccatccg gagtccagtt aggtgcctcg
      481 atcaaaaaag ggaattcctt gacaacggaa cgttgcccgg tcgtaatgtc catcacttcc
      541 agcacactag tcacattctt tttttgggca tgcgtacaaa aaacggcgat acacatacaa
      601 agtacagaat tgagaaaacg tttcatatac atatagattt aaaggatata agaaaaccgg
      661 gtaaaattag ctttacgcta ttttacccgg tttcaaagat ataatttatt tcgattactc
      721 cttatacatt gaaacggaaa tgcatgatat ctccatcttg cacaacatat tccttacctt
      781 caatgctcat ctttccggcc tctttaacag cagcctcgga gccataagcg atataatcct
      841 cgtacttgat cacctcggca cggataaatc ctttttcgaa gtccgtatgg ataacaccgg
      901 cgcattgagg agctttccag cctttatgga acgtccacgc acgacattcc tccgatccgg
      961 cggtcaagaa ggtttgcaga ttcaataatt tgtaagccga tttaatcaaa cggcttacgc
     1021 cagactcttc caatccgatc tcttgtaaga acatctggcg ttcctcatag gtatcgaact
     1081 cagcgatctc gctctcgatc ttagcggcga ctactagaat ctgggcatcc tcgtctttaa
     1141 ccgcctcgcg tacggcatct acatatttat tgccgtttac ggcgctagcc tcatccacgt
     1201 tacaaacata catgacaggt ttatccgtca gcaagaataa atcgtgggca atgcgttcct
     1261 cgtctttcgt atcaaaagaa acggtacgtg cgctttttcc ttgttctaaa gcctctttgt
     1321 atttacaaag tacctcgtaa gcgatcttgg cttgcttatc acctccggtt tgcgcttgtt
     1381 tttgcacctt ggcgatacgg ctgtctatcg tttccaaatc cttgatctga agctcatagt
     1441 caatgatctc cttatcacgg accgggtcta cacgtccgtc cacgtgcacg atattatcgt
     1501 cgtcgaagca acgcaatacg tgcaagatag cgtctgtctc acggatatta gccaagaact
     1561 tattgcctaa tccctcgcct ttactcgctc ctttcaccaa tccggcgata tccacgatct
     1621 ctacggtggt ggggatcact cgctgcggat gttcgatttc cgctagttta ttcagtcgct
     1681 cgtcgggtac ggtgatcacg cctacattcg gttcgatcgt acagaacgga aagttcgctg
     1741 attgtgcctt cgcgttggat aggcaattga aaagggtaga ctttcctacg ttcggaagtc
     1801 ccacaatgcc acattgtaat gccatattat tatcgtattt tttattatca atctgttata
     1861 tagtcgctcc aagcgacttg ttttgagttc gcaaagataa tcaattttag gctgatacgg
     1921 ttattttctt aggctttctc ttcatgctta accggttgcc tcatcgattg tttgtttaat
     1981 aatgttttaa cgagtttgtt cataggcttc tttactaatg ttatttttta cttaggttgt
     2041 tctctcatat ttccggtaaa agaaagtcaa taacaagaat ccgataaaag cgaatccgga
     2101 acctatcaag gccggatatt tataaccaag gccgacctcc aatggtaacc caccacaata
     2161 agctccgata gcatttccta aattgaacgc aacttgtacg ctggcggctc ccagcatctc
     2221 tccacctttg gagtaacgga tcaataatac ttgttgaggg cttgagacgg cgaataatcc
     2281 cgccgtacac agacacatca gcaagacatt taaccaagat atttgtgcca agaagaagac
     2341 gagcagtagg gctacgcaaa tcatgccttg cgctatggcc gctacccgtc cgggcatata
     2401 tttatcggat aggcggccac tgatcaagtt gcccgctacc ataccgaaac ctgccaatac
     2461 cattagaaca gtaaggcttt cggccgagaa gccggatact tgtgtcaata gcgggctgat
     2521 atagctatac cagcaaaata cacctccgtt acctagcatt gtcgccccta ggattaacca
     2581 tggcgcttga gtcttaagaa aacgaaattg tcctttaaag ccagtatccg gaaggttctc
     2641 taccataggt acccatctcc agatgtaata taagatggct atgccccagc aaccaaccag
     2701 taagaaagtc agacgccacg agagcatggt gctgagggcc gtccccaacg ggacaccgaa
     2761 taggttggcg atcgtcatcc ccgctatcat gatagagaca gcctcggagc ctcttccttt
     2821 atcagcaagc ttttcggcta cgatggagcc aacaccgaag taagctccgt gaggcaatcc
     2881 agagatgaag cgggctatca tcaataccca gtaattagac gctaatgcgg cgcataaatt
     2941 accgatcatc ataatcccta ctaaaacaag caaaatgtgt tttaatggat atctacgggc
     3001 gataatcaac atgggagcgc ctacgcaaac ccctagtgca taagctgaga tcagatgccc
     3061 ggctgtagca atgctgatgt gtaaatcttt cgcgatgtcg ggtaggatac ccatcattac
     3121 gaactcggca atccccagcc caagggtacc gaaagctaaa gcgatcaaac tttttttcat
     3181 aacctaaaat gctcaacaat cttttcgagc gcaaatatag tgtatagtat acattattat
     3241 ttgcttttcg gaatgttttt aggggaaagt tttgcgtttc gtgatgggct gttagggtct
     3301 taaaaaaaca tgtacgtctt tcaagaaaaa gtcgtacgtg ttttcaggaa aacacgtaca
     3361 tgttttttta aggggaattc cggcattatt ttaatgcgcc tccaaccagt tctctccctc
     3421 gccgcaatcg gcgatcaagg ggacttgtag tttcatgacg ttttccattt cctccagcac
     3481 gattttcttt acctcctcgg cttcctcttt gtagatattg aagtttaact catcgtgtac
     3541 ttggaggatc atcttgcttt tcaatccctc ttcctcaaag cgttcgtaaa tgcgtaccat
     3601 cgctagtttg atgatatcgg cggcgctccc ttggataggg gcattgatcg cgtttcgctc
     3661 ggcataaccg cgtacgacgg cgttgtgtga gttgatatcc ggaaggaaac gcttgcgctt
     3721 gaaaatggtc tctacgtatc ctttttcctt ggctaccttg atgctctcct ccatgtattc
     3781 cttgatgcgg gggtaggtgc tgaaataacc gtctatcagt tccttggact cagaacgagg
     3841 gatgcccaga cgctcggcga gcccgaagac ggagatgccg taaatgatac cgaagttggc
     3901 ggttttcgcc ttccggcgca tatcgctggt tactttttct accgggattc cgtagatctt
     3961 ggcggcggta gcggcgtgga tatccgctcc gctttggaaa gcctcgatca tatgcgggtc
     4021 accgctcagg tgggccatga tacgaagctc gatctgggag tagtcggccg agaagaagag
     4081 gcaatccgca ttatccggga taaacgcctt acggatctcg cggccaagat cgtcccgtac
     4141 cggaatgttt tgcaggttcg gattggtaga gctgaggcgt ccggtagatg ttaccgcttg
     4201 gttgaaagag gtatgtatct ttccggtctg cggattgatc aactcgggta gagcgtcgat
     4261 ataggtactt aataattttt taagtccgcg gtattcaaga agcttgccga tgatgggatg
     4321 tttgctgcga agtttctcca atacatcctc gctggtactg taaccgcctg ttttggtctt
     4381 cttcgctttc tcgtccagct tcaagcggtc gaaaaggatt tcgccgacct gtttcgtgga
     4441 gttgatgttg aattccgtgc cggccagctc gtaaacctct tgctccagtt tgttcatgga
     4501 ggcggtaagt tcgcccgaag attgcttaag cgctactgta tccagcgtga cgccggtagc
     4561 ctccatttcc actaatacat atattaatgg catctcgatc gtggtgaaga gggattccag
     4621 tccttctttc ttcaactcgg gcgcgaaata attctttagc ttgagcgtga cgtctgcatc
     4681 ctcggcggcg tattcggcga tttgttccac gggtacgttt cgcatcgata actggttctt
     4741 tccttttggg ccgatcagtt cctcgatgtg gacggtctgg tacttgaggt aggtctccgc
     4801 taggtaatcc attccgtgcc gtaattccgg gttcagcagg taatgggcga tcatcgtatc
     4861 gaacagagga ccggctacct tcacgttgta tttacgaagt accaaaatat cgaatttgat
     4921 gttttgcccg atctttaatg atttcggatt ttgcagggca ggggagaagc gttccactac
     4981 tttcgccgcc tctactgagt tggcgggaac aggaacatac caagcctcgt tttctttcac
     5041 ggcgaacgac attccgacca gtccggcttt caagggatcg atgccgtcgg tttccgtgtc
     5101 aaaagcgaaa aattcttgac ccaataaaaa gcgggctaaa tcggcttgtt tttcctctgt
     5161 atcagttaaa taatagttgt gaggggtgga ctttaagtcc gtgagaatcg atttttttgg
     5221 ctcttccgta ctctcgggcg taaaaatcgc gaacaaatcg ccttgaacgg gacctttcgg
     5281 agcggctttg accggctcag aacttagttt gttaataaat gttctaaatt ccaattctgt
     5341 gtaaatctca gtcaggcgct cttcgtttgg cttttcacga acgcaacggg cggcatcaaa
     5401 ctcgataggg acatccgttt tgatcgtcgc caagaatttg gagaaatgga tttgctcggc
     5461 gttctcctcc accttcttct tttgcgcgcc tttcaactta tcagtgttcg ctaacaggtt
     5521 ctcgatgctt ccgaattcgg tcagtagttt ttgagcggtc ttctcgccga cacccggaca
     5581 gccggggata ttatcggaag cgtcgcccat cagtcccagc aagtcgatca cttgctccgt
     5641 actcgtgagg ccgtacttgt ttaagacctc aggcacgccc atgatctcgt aatcgcctcc
     5701 gaatttcgga cgatacataa atatatgttc ggacaccaat tggccgtaat ctttatccgg
     5761 cgtcatcatg tacacctcga agccttcctt ctccgcctgt ttggatacgg tgccgatcac
     5821 atcgtccgcc tcgtagcggg gtacttccag aatcggaata ttgtaagcct ctatgatttc
     5881 tttaatgata gggacggatt gacggatcac ttccggcgtc tcttcccgtt gtgccttgta
     5941 ttgctcgaag gcctcatggc ggaaggtcgg tcccttcggg tcaaaggcca ccgctatatg
     6001 agtcgggttc tcacgtttta atacatcctc cagactgttg ataaaaccga aaatggcgga
     6061 ggtattcaca cccttggagt tgatacgcgg attcttgatg aaggcgtaat aggagcgata
     6121 aattaacgca tacgcatcta taaggaataa cttcattact tttaacacgt tttagtggga
     6181 caaaatctgg gtaaatgtac gaaaaaactc gcttactcga tagtttttgt tacttttgcg
     6241 aatctttgca tggaattatg gatgaaagaa ggaaaataga agaaccggtt tccgctgaat
     6301 ttgaacgttt caataaggat ttcgaggcat ctctacgcag cgagacgacc cggttacaat
     6361 cggctatcga cgttatactg aattctaccg ggaagcatgt gcgtccgtta ttggtgctcc
     6421 ttaccgccaa ggtctgtgga caggttacgg ataacacgat caattccgct gtcttgctgg
     6481 agcttttgca taccgccacg ttgattcacg atgacgtgat cgatgagacg aagcaacgtc
     6541 gtggcgttcc ctcattgaac gctatctttg ataaccgtat ttccgtgttg gtaggtgatt
     6601 atgtgctttc taccgctttg atccgttcca tacaaaccgg cgatttgcgg attgtcggga
     6661 ttatctctaa tttaggcaga gacttgtccg aaggtgagat caagcaattg gagaccgccg
     6721 aggagagtat cctagacgag aattgctatc tgcaagtgat caagaagaag acggctacct
     6781 tgctttccgc ttgcacggag attggggcca tttcatcggg cgcctctgcg gaggtgatcg
     6841 ctctttgccg tgagtttggc gagtatctgg ggtattgctt ccagatcaag gatgatatct
     6901 ttgattattt caaggaggcg aatatcggta agccgacggg aaatgacatt cgtgagggta
     6961 aggttacgct tccattatta tatgccttgc ggcagggtag ggaagaggag gccgcccgtt
     7021 atttggatat gattttacgg aaagatttcg cggcggagaa tgtcgattcc ttgatcgagt
     7081 tcgccaaggc gaatggtgga atcgaatatg ccgaggcccg catgaaggaa tatcatgata
     7141 aggcggtcga tgttcttttg agattgccag agtctgaggc acggacatcc ttgatccagc
     7201 tggccgatta tatcatgact cgctccaaat agaaattcct ttatctatta gttgtagaga
     7261 gatggctctt gttcgtaaaa aagtaagtat gcttcaatag ccaatgaagt taacttactt
     7321 gacgaagtca gttaacttcg atgccaaggt aagttaactg actttgagag tgcttaccgg
     7381 acacaggatt ctaagccatc tgcgcccggt ttattagaat ggactatttc ccgagtcgtt
     7441 tttctatatc accgaccaga ctgctcgctc ctatacggaa caaatctttg ttaagccatt
     7501 catcgcctag tatctccttt acgatcgtat aatatcgaac tgcgtcttcc gccgtgcgta
     7561 cgcctccgga gatcttgatg ccaaccttgt ttccggtgat ggaatggtag gttttgatgg
     7621 ccttgcacat ggtataggcg gcctcgaaag tggctcccgg gtatcctttg ccggtagagg
     7681 tcttgatgaa gtccgcgccg gaatacatgg ctaggatgga tgctttttgg atgttctccg
     7741 ttgtgactaa agctccggtc tctaagatta cctttaaatg ggcgtggcga cagctctcct
     7801 tgatctcttg caattcctcg gtcaattcct cgaaattgtc ttccatgaaa tagcctaggt
     7861 tcatgacaac gtcgatttca tcggctcctt gcatgactgc catggccgtt tcggcgatct
     7921 tgacttccgt aaatgtctgt gaggaaggaa aacctccggc aaccgacgcg atcttaacct
     7981 cttgcgcagt aagtgcctgc ttaaccgttt ccacgaatag gggatagacg caaatagcgg
     8041 ctacgttcgg gacatccgga cgagttccct cgaaatcatt taccgtgtcg accatcttcc
     8101 agatgttttc tttggtatcc agactggtca atgaggtcaa gtcgatgcag ccatgaatcg
     8161 ttttcaatac ttccggtgta aagttttctt ggaaatgttt ctctaaaaga gcgtttacag
     8221 tctcggtggt ctgggtatcc ggcagggccg gctcaaactt attgaaagct tcatgataac
     8281 ggtctatctg tacggaattt gattcgtgtt catgttcatg atgatgatca tgtccacatt
     8341 cgcaatcgtg atgatgtgcc atatgcttat agtttttgat tgtttatatg tcgttcttta
     8401 tctcggtctg ttttcttttg gagattcttc tcgaaagcgg cggtaagatc tactccggtc
     8461 tggttggcga ggcaaagcag tacccataag acatctgcca tttcatcgcc taaatcccgg
     8521 tgtttgtcac tttccttgaa agactgctca ccgtaggtac gtgccatgat ccgggctagc
     8581 tcgcccactt cctcggtgag gatggtcata ttggtaagct cattgaaata acggacccca
     8641 taggtcttga tccaagcgtc taccatttgc tgggcttgtt gtaaagttat atctgccata
     8701 cttattcttt attttgagag tcgataataa tagtaaccgg cccgtcgttt aaaagttcaa
     8761 ttttcatatc agctccgaat gttccggttt gtacaggttt tccgagttga agccctacct
     8821 cttcgcaaaa agctttatac atcggaatgg cgatatccgg tttagacgct tttaagtagg
     8881 aggggcggtt cccttttttc gtagaggcgt gtaaggtaaa ttggctgaca accatgatct
     8941 cgcctcccgc ttcgataacc gagcggttca tgaccccgtt ttcatcgtca aatatgcgta
     9001 ggttggtgat cttttttgcc aaccattcaa tgtcttcttg cgtatccttg tcctcgatac
     9061 cgactaatac caatagcccc tttccaattt tggacttaag ctgtccgtct atcgtgacgg
     9121 aagcgtgctg cacacgttgt gtaactgttc tcatcttgtt cgcttttgtt ctatttttgt
     9181 tcgctttctg ttcgctttcc atccagtccc tcttgtagtg ccttggcttt cgcctcgcca
     9241 atcacggatt tcagttcctc gaagcttgct tccttgattc gttttacgct tttaaagtga
     9301 cgtaaaagta atacttttgt cttttcaccg atacccttaa tggtgtctaa ttcggatttt
     9361 gtctgggtct tacttcgttt atccttgtgg aaagtgatgg cgaaacggtg tacctcgtct
     9421 tgtatccggg taagcagatg gaatagcgga ctgtccaaac gcatgccaac ggttacgggt
     9481 gggaacccga ataataactc cgaggtccgg tgcttaccat ctttcgctag tccggcgatt
     9541 ggaatggaca agcctaattc atcttctacc accgagcgaa ccacttccat ttgccccttt
     9601 ccaccgtctg ttataattaa gtcgggtagg ggagatcgct cctcgattgc ccgcccgtaa
     9661 cgcctacgga caacttcttt catagaggcg taatcatccg gaccgactac ggtctttata
     9721 ttgtatttac gatactcctg cttggacggt tttcccatct tgaataccac gcaagccgct
     9781 accgcatcgc ttccctgtat gtttgaatta tcgaaacatt cgatatgagc aggcaatttc
     9841 tccagatgca aggcctcttg gatctctttc aagatacggg tattccgttg ttccggattc
     9901 aacttttccg cttgcttcaa gcggtcaacc ttaaactgct tgacgttcat ctcggataaa
     9961 tcgagcagtt tctttttatc ccctctttgg ggaatggtga aggtgacatt ctctagttgc
    10021 atatccagct tgaaaggcac gataatctcc cgggcggtgc ttttaaaacg attccgcatc
    10081 tcgataatac cgaggcttaa caattcctcc ttactctcgt ccaatcgttt tttatactcg
    10141 aatgtatagg cttgtacgat cgccccgttt ccgatatgca taaagttcac ataagcggaa
    10201 tggtcattct ctatgatcgt gaatacatct atattatgta gcatcggggt tacgaccgta
    10261 gatttagaac ggtagttctc gatgacttcg tatttttcct tgatcttttg cgcttcctca
    10321 aacttgagct cggcagcgag cgattgcatc tcctcataga ggtgtttgct gatttgcgag
    10381 atgttgcctc gcagaatctc tttgatctcg gaaatatttt gctggtattc ttccaatgat
    10441 tgcaagcctt cacaaggccc tttacaacgc ttgatatggt attccagaca aaccttatag
    10501 cgtccttgtg cgatggattc gggagtgagg ggatatttac aagtgcgtaa agggtaaagt
    10561 tcctttagca tttgtagcat cactttcgcc gtgaacaaag agggataagg accgtaatat
    10621 tgtgatccgt cccgaacgat gttccgggtt tggaaaaccc ggggaaagta ctcgttcttt
    10681 accacgatgg aagggtaggt tttgtcgtcc ttcaataata cgttatagcg gggacgatac
    10741 tgtttgatga ggttgttttc cagtagtaac gcgtcttctt ccgtatcgac gactatatat
    10801 ttgatatccc ggatttgctt gactaacaca cgggtcttat tgctgtcatg taccttgttg
    10861 aaataagagg atacccgtcg ttttaggttc ttcgccttgc cgacgtatat aatcgttccg
    10921 ttttcatcga aatactggta gcatcccggc ttttccggaa tgaccgatag gatcgtcttg
    10981 atatgttcgt ctttatcggc tatcatacga atagggaagt aaattggaat gtctcgctat
    11041 tgaacaaacc tttgttgcta agttttaagg atgggatcgc cagcaatccc ataaaagaaa
    11101 gcgtcatttg taatgaatcc atcggggatt ttaatcgctt gatcttttcc tcgatctctt
    11161 cgtaacggca gctcgtctct tccaatgatt cgtcgctcat caatcccgct accggcaagg
    11221 acaggagagt gacttcgtcc atgcagctca cggcgattcc tcctttcgct tttatgacca
    11281 cattgatcgc ttgcataagc tcgaaatcgg ttacgcctat agcgatgatg ttatggctat
    11341 cgtgggagat actttgagcg atggcaccga gcttgagccc tgttcctttt ataaaggtaa
    11401 tagcgggagg agccgtttga tagcgattta gaataacgag ttttaaaatg tctcgttctg
    11461 tatctgattc tacaaatcca tcgaatgtat gtacaggata tagttcttct ttcgtgatta
    11521 attcgctgtc ttcgcaaaca atgacacgca tctgttcccc tttcgctttt accgctagct
    11581 tttctaatgt gatcggtttc gtgtggaaat tattacgatg tataggcttt tggagtggaa
    11641 gcgtgcattt ctctccatcg tatacacagg ttccttgtat ataggttgcc tgtatggtta
    11701 gatcctttaa attgtttact tggataaaat cggcggagtc tccctctcgt aagaaacctg
    11761 cggggatttt atagtgcatg gccggattat aggaagcggc ccgtaataca tcatatagat
    11821 catatcctaa atccagcgat ttttttacca tcctatttat gtgtcctttg tttaaaaacg
    11881 aaggatgtgc gtcatccgta cagaacatga tttgttcggg atactctttc aatagcggat
    11941 gaagtgcgtc aaagtttttc gccgcgcttc cttcccgaat aagaacatgc atcccaagct
    12001 cacatttctc acggcctttt tctagataga tggtttcatg atcggtggaa ataccagact
    12061 cgatatatgc ctttagcttg ggacctgtcg ctaggggata atgtccgtct atgggtttac
    12121 ccgcttgttt cgcggcttct attttgcgca taacttccgg atctttattt aagactccgg
    12181 ggtaattcat catctctgcc aagaagtgta gatcctctcg ttccaacaaa cgagcggttt
    12241 cgtctgcgtc tatgatcgca ccggaggttt ccataatcgt agccggtacg caagatggga
    12301 caccgaacca tgtgtagaaa ggaatccctt tcgcgttgtc gagcatatat tcgactcctt
    12361 cggtacccat tacattcgct atctcatgag ggtccgccac ggcaccgata ctgccatggc
    12421 gtacggctgc gtgaatgaat gccgtagggg ttaccatgct actctctata tggacatgtg
    12481 cgtcaataaa gccggggagg aggtaatatc cctcatcttg tccggtaggg gttacctttc
    12541 cgatatgccc gtttaggatt gaaatctctg ccccgaaggt gcgcctgttg attatatcta
    12601 ccagatttcc tcgtataacc agtgttttag cttcattcat ttgaatatct cctttaatat
    12661 gtttcacgtg gaacatttcg tgttttatct tccgagtagt accaaaagga tgttgatgtc
    12721 gctaggggaa atacccggga tgcggctcgc ttgagcgatc gtgtcgggat ctatccgggt
    12781 caatttctgg cgggcttccg tagataaaga ctggatcgag ttgtaatcga atttaccctt
    12841 gatccggata ttctctaaac ggtttatctt atccgctatg atttgttctc gcttgatgta
    12901 gccgctatac ttaatcaata tctcagcggc ctcgatgatc tcttccttac gggaggccgg
    12961 gactttgtcc agctccgcac gaagggccgg aactagatct gcgaggtttt ccaatgtagt
    13021 ctgcggacgg agtacgacat cgaataattt gcaaccatgg gatagggggg ctgtacccag
    13081 tttctccaaa ccgctgttta tatattgagg ctttacggag taggtctccg caaaacgaat
    13141 gatagcgtca cggctctctt ttttctctcg cagtaaatcg tagcggtctt gtttggccaa
    13201 tcccatttgg tgggatttct cggtgagtcg catatccgcg tcgtcttggc gtagtaagat
    13261 gcggtattcc gcacgagagg tgaacatacg ataaggctcg tccacgcctt tggttaccaa
    13321 atcgtcgata aggacaccga tataagcctc gtctcttccg aggataaaag gttgtccgcc
    13381 gtggcaattg atgtgggcgt taatacccgc taccaaacct tgtccgccgg cttcctcgta
    13441 tccggtagtt ccgttgatct gtccggcaaa gaaaagatta cggatttgtt tggtctccaa
    13501 attatgtctt agctgagtcg ggtcgaagaa atcgtattca atcgcatatc cgggacgata
    13561 gatttgcacg tcacggaaag cggggatcgc ttggagcgca cgaagctgga tatccaaggg
    13621 tagggaagag gagaagccat ttaggtaata ttcttgcgtg gcctcgcctt ccggctctag
    13681 gaatagttga tgctgcgtct tgtcggcgaa cgtcacgatt ttcgtttcga tgctgggaca
    13741 ataacgggga ccgatacttt tgatctgtcc attataaaga ggagagtcgg ggagaccttc
    13801 ccgtaatata tcgtggcaag cctcgttcgt aaaggtagtc cagcaactca attgttttaa
    13861 tttacgatga ctggtatcca tgtaagagaa cttatggaaa tcgttttccc ccggttgttc
    13921 ctccatttca tcgaagtgaa cgctccggcc atcgatacgg accggtgttc cggttttcat
    13981 gcgatctgtt tggataccta aagagacaag ttgctcggta agtccggtcg ccgcaggctc
    14041 ggcgatacgt ccgccccgta tctgggttct tccgatatga agcaggccgt ttaggaaggt
    14101 cccgttcgta agcaccaccg ctccggcacg gaatacgaca ttcattcccg tacggacgcc
    14161 gcagacttgt ccatgctcga taatcagttc ttgaaccata tcctgccaga tggatagatt
    14221 cggcatattc tccagtatgc cccgccagca atcgataaaa cgggcacggt cgctttgggc
    14281 acgcgggctc cacatggccg gtcctttgct acgatttaac atacggaatt ggatagcggt
    14341 ctggtcggtc acgattccca tatatccgcc tagcgcatcg atctctcgta cgatctgtcc
    14401 tttggcgatt cccccgactg ccgggttaca actcatctgg gcgatcttgt tcatgtccat
    14461 cgtgatcaaa agcgtctttg atcctagatt cgccgcggcg gcggcggctt cacagccggc
    14521 atgtcctgcg cctactacta ttacgtcgta attgaaagtc atttttattc ccttttattt
    14581 tacgcgaaga tagtgagtgt tcgtgaaaga attcgtttat atttgtataa taaatacata
    14641 cattgttttc aggtttaatg aactaaagat ttaagctgct atgaattcta ttcaatgccg
    14701 tatccttgtt tttctggttt tactgacctc ttgcttcagt ccggtttgtg ggaaagataa
    14761 gaaacctcgt caagcgatcg agaagttatc gatcgatggt ccctatctat tgaaagccga
    14821 tgatggtagt atgcgtgcga tatctgtaga cgggaaaggc cggttattgg ataagcatta
    14881 taaaagtata cctaccacct tttcattcga ggtgttttcc gataacgggg agagattgtt
    14941 tccggtaacc atacactccg tctctcgtcc gaaatggaaa gatgtgcaac cagagaagac
    15001 gtttgttctt tcagatccac atgcgaactg gtcttgtttc gcctccctgt taaaggcggg
    15061 aaaagtgatc gatgcggact ataattggat tttcggggcc aaccaattgg tgataatcgg
    15121 tgacgtcttt gaccggggcg tggatgtact ccctatctat tggttgatct acaagttgga
    15181 gaaagaagcg gaagatgccg gtggaaaagt gactttctta atcggaaatc atgagactat
    15241 ggttctggga aatgatttgc gatatacgaa gaagaaatat actcaattgg cggatacttt
    15301 aggaatgacc tatccggagc tttggcagaa aagcgagtta ggacattggt tgaaaactcg
    15361 taactcgata caggtggtcg gagataacct gtttgtccat gctgggttga gcaaggagtt
    15421 tttagaccgg aattacgata tccctaccgt gaatgagatc gtgagcgatg gcctcttctt
    15481 aacgaaaaaa gaacgtaatg cagataaagg ctccgatctt tcttttatgt tcgctacgta
    15541 tggaccgatc tggtatcggg gtatggtacg tagcgcagat aagtatcacc cgttagatcg
    15601 ggatgatttg cggaaaatat tagagaaata taatgtgaac cgcatctttg taggtcatac
    15661 tattttcgat gatatcacga ctttctatca ttataaagtg attgccgtga atgtcgataa
    15721 tcaagaaaac aaggagaagg aacgaggccg tggtgtcatg atcgagaaag acggttctat
    15781 gtttgtcgta tatgattccg gaaaacaaga gccgttatta accgagtaat atttggtgct
    15841 tgagctgtca cggctgctac catcatggtg gaggaagaag tgcctcccct aatgtgaagt
    15901 aatgagatag ggagtgcaac ttttatgtat cttaaatcat ctataaatat agatatgttt
    15961 taaatgtagg agttatgaaa aaagttgtat tactgtttat cttgtttgtt ttctctttgt
    16021 cgcaagccga tgctcaagag ttccatttta ttcctaggat tggcttgaat ttggcaaata
    16081 cttatccgga aagttttgcg gatatgcgtc cggggttaaa tattggtgtg gcggaggaaa
    16141 tacgttttag taaactgttt gctttagaac cgggtgttta ttattctatg caaggttatc
    16201 aacaggaaaa cgctaaaggc gagacagccc ggctaaaggc ggattattta aatattcctg
    16261 tttacgctaa attttatttg tatcggggat tccatctttt cgcgggccca caagttggct
    16321 ttaatgtaag ggcgaaagct tcgaattata ttttcgtctc ggctcctact ccggtgcacc
    16381 agagcgagta cgatttttcc ggtgataaaa aagaagagat ccgaaattgt gatttctctg
    16441 tttcgatggg gcttggctat acgtttgaca tgggattagt tatctccgcc aattataatt
    16501 taggatgtac tcatttcttt aaggagccgg aatactcatt cggtggaagc aatcatttta
    16561 ggggaaaaga tcataatggg gttattcaat tcaatctagg atggcgtttc tgatctccag
    16621 taaatcgtga attaagagag atcgcttgtt cctcgttcag ccttgcggca tggctacaca
    16681 ggcaatggac tgctttcggg cattgctcgt ccgtggcgta gcaatacgtg taatcgtaag
    16741 gtatgtcttc tgttttcatg ttgtctgtat tatttttatt tatttcaaca atagtctgct
    16801 ctcaaccgcc tctaatatct tcatttgctg gatcgctatt tgattaagct ttattagtcg
    16861 ttcacgctgg gtaagtcctt catcaataaa tacagcattc aggctttcca tattcgataa
    16921 acagataagt tcattaatag tcgcatagtc acgaatgtta ccttttaatt cgggattggc
    16981 ttcccgccat tgtttagcgg ttgtgccgaa tagagcgaca ttaagaatat cggcttcgtt
    17041 tgcgtatata aagcttacct gttgcggggt taactctatg gggatgagat tatgcttgat
    17101 agcgtcggta tggatgtgat agtttatttt ggagagttct cgtttggcag tccagccgat
    17161 ttgtttctgt tcctcttctt ttaggcgttg aaactcttta acgatatata attcaaattc
    17221 aacagagatc caacttgcga atttgaaagc tatatcctta tgagcaaagg tgcctccata
    17281 tcttccggat ttggagataa taccaattgc cgctgttgta tttatccatt tttgtggaga
    17341 aagggtaaaa gcatttaacc ctgcttcctt tttaaacccc tcgaattcga ggggtttaaa
    17401 attaggatta tataaacttt cccatatacc taaatattca atggtattac gattacgcat
    17461 ccaattgcca attactgctg tcggatcatc gcttttgtac tttgcgatgt cggtaagtga
    17521 gatatagtca ttcttattta tagatatgat catgacactt gtattttgga ctgtgatttt
    17581 ctccataatt ttcttcagat aagatttgta gtataaattt gtttctggtt aacatctctt
    17641 tactgacatt cctccggcaa gatcgctaac gctctgttct cgttctcctc catgatctcc
    17701 cgctcgccgg ggcctttgtc gttgataccg caaaggtgca ggatgccgtg gatgatggta
    17761 cggtggagtt cctcgttata atccgtgtgg aatgtctcgg cgtttgtcct gaccgtatcg
    17821 aggctgatga acaggtcacc cgagatctta tttccttccg tataatcaaa ggtgatgata
    17881 tccgtgtaat aatcgtgttg gagatattgg cggtttacct ccaagatctt ctcgtccgag
    17941 cagaagatgt aactgatatc gcctgtcttc ttcccgtagg tctcggctac cgccttgatc
    18001 catccgctga ccgctttttt cttgattgcc gggagctgga tatcctcggc gtaatatgct
    18061 attgccataa ggtctattta tcgtattgaa atttcgttac aaatgtaatc aatagatttt
    18121 aaatagattc atttcaaatc tattgattgt atagaatgtt aaaagaacag gtaagccatc
    18181 gctatcgccg ctatcgcccc ggccagatcc gctaacaagg cgcattgcac cgtatagcgg
    18241 gtattacgga tacctacgct accgtagtaa agagcaacta catagaatgt cgtatcgcaa
    18301 gagccctgaa cgatggatga caggcgaccg acgaaagagt ccgctccata cgtgttcatg
    18361 gcgtccagca tcatgcccct agccccgctc ccgcttaacg gtttcatcaa catggtaggt
    18421 agcgcttcca cgaaatccgt gttgagccct atcgaagcaa tgccgaaacg aacgccttgt
    18481 atgatgaaat ccatcgctcc ggaagcccgg aagacaccga tacctactag gatagctacc
    18541 agataaggaa taatcgttat agcagtctgg aaaccttctt tcgccccttc tataaaagca
    18601 tcatatacat tgatcttttt acgcatgccg ctgatgataa atccgcagat aatggtaaaa
    18661 agaagcgtgt tggcgaataa agtcgaatac aaggaaactt gctcctgttc catcgagtta
    18721 aatagccata ccaggcctcc gataaataat cccagtcccc cgaaaaacag gactaggttc
    18781 cgttggagga tattgatctt ctgccgtacg caaaccgcta aaatagcgac taaggttgat
    18841 gtgaatgtag cgagcatgat cggcaggaat acgtctgatg gattcgccgc tcctaactgc
    18901 gcccggtaca tcatgatggt gatcgggatc aaggtcagtc ccgaggcatt gatgcataag
    18961 aacatcacca tggagttgct ggcggattct ttattcgggt ttaattcctg taactgttgc
    19021 atggctttca atcccattgg cgtggcggca ttatccagtc ccagtaaatt tgccgatagg
    19081 ttcatgaaga tagaaccggt cacgggatgg tctcttggga tatccggaaa aagcttgctg
    19141 aatacgggag ccgccaatcg tgcgaacgct tgtatcaccc cccccttctc
//
LOCUS       DBMDTB010000080        18561 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_983_length_18561_cov_11.129902, whole genome shotgun sequence.
ACCESSION   DBMDTB010000080 DBMDTB010000000
VERSION     DBMDTB010000080.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 18561)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 18561)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18561
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_983_length_18561_cov_11.129902"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            17..1342
                     /locus_tag="ACZPB4_12350"
     CDS             17..1342
                     /locus_tag="ACZPB4_12350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005681302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HIR1099037.1"
                     /translation="MGAKKNFVLDTNVILHDYKCIENFQENDIYLPIVVLEELDKFKK
                     GSEQINYNAREFVRELDLLTSNDLFLKGASLGPGKGTLYIVTGDKYQEKIAHSFPDKT
                     PDHRILSCALTIAEKNPKIKTTLVSKDVNLRMKARSLGIPVEDYITDKVVNVDIFERA
                     QETYENIDPDLIDKIYSSPEGVDADSLDIKSKLDPNECFILKSVRNSVLARYNPFTDK
                     IKKVDKGTNFGIQPRNAEQSFAFEVLNDPNIKLVGLTGKAGTGKTLLALASALKQAGT
                     YKQILLARPIVALANKDLGFLPGDEKQKVAPYMQPLFDNLNVIKTQFAPGNPDVRKID
                     DMQKNNQLVIEALAFIRGRSLSETYCIIDEAQNLTPHEIKTIITRAGEGTKMVFTGDI
                     QQIDSPYLDAQSNGLAYMIDKMKGQDLFAHINLIKGERSELSELASDLL"
     gene            complement(1416..1805)
                     /locus_tag="ACZPB4_12355"
     CDS             complement(1416..1805)
                     /locus_tag="ACZPB4_12355"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004497 - monooxygenase activity [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative quinol monooxygenase"
                     /protein_id="HIR1099038.1"
                     /translation="MKKVFISMACVLIALSGCTNGGSNKESMEVVLNIKRKVKPECVS
                     ALKESFLKCKESTLLEPGCIDYGMYQSLTDSTEFFIAETWKNDGELQKHGETAHLKQH
                     LNEIKDMGDPSYKGSFRKIYVCPSVND"
     gene            1969..2355
                     /locus_tag="ACZPB4_12360"
     CDS             1969..2355
                     /locus_tag="ACZPB4_12360"
                     /inference="COORDINATES: protein motif:HMM:NF027597.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4925 domain-containing protein"
                     /protein_id="HIR1099039.1"
                     /translation="MRKSLLYVFAVICTMGFFTACGDDDDSSSSGNWQDLSKTYEGKS
                     VNLVMGEVTVPVDGKSVVIAASSAEKASVTLNNIIPENKSVAIDAALKEADGTYTFTG
                     ESTVGDCVVSVNGTVKGGRSFCCLYS"
     gene            2399..2974
                     /locus_tag="ACZPB4_12365"
     CDS             2399..2974
                     /locus_tag="ACZPB4_12365"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099040.1"
                     /translation="MEAIYANIVTGNSTIDDLMRMIKPAISNLIWGKVSAVNVNLPED
                     GIFDVSWRPIGASEDKGIGEITKMASIQYCVVDGKFMVAVDKNYVTVLTTLLQQAAGD
                     KLEAAGISIDEIMKLLVDLGGYYGLPLNMKVDGSEATFYADKDLIVPVLTMIAPILKP
                     MVPENYQQMVDMVLQLLPNAKTLEFGLNFTK"
     gene            complement(3066..4151)
                     /locus_tag="ACZPB4_12370"
     CDS             complement(3066..4151)
                     /locus_tag="ACZPB4_12370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005638712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LptF/LptG family permease"
                     /protein_id="HIR1099041.1"
                     /translation="MKFKLKRIDWYIIKQFLGTYVFAIALIISISVVFDINEKIDKFL
                     NPDVPLKAIIVDYYLNFIPYFANLFSPLFTFIAVIFFTSKLADRSEIIAMLASGMSFR
                     RLMLPYAVSATIIAIVTFILNAYIIPPANETRIDFQNKYIRNKKVDYVKNAQLEIEPG
                     VIAYFDSYDARSNMGYRFSLEHFEDKKLISRLTAKSIKYDSLYQWTVIDYMIRDFDGM
                     REHISQGSRKDTTLTIVPSDFLISVNDCETMTTPELNTYINRQKKRGIGNIQTFQIEY
                     HKRFATIMAAFILTSIGASLSSRKIKGGMGMNIGIGLALSFSYILFMTVTSTFAINGY
                     VSPAVAAWIPNIVYTFIAIFLYQKAPR"
     gene            complement(4164..5294)
                     /gene="tgt"
                     /locus_tag="ACZPB4_12375"
     CDS             complement(4164..5294)
                     /gene="tgt"
                     /locus_tag="ACZPB4_12375"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002560222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008479 - tRNA-guanosine(34) queuine
                     transglycosylase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HIR1099042.1"
                     /translation="MTFELQYNDTKSNARAGLITTDHGVIETPIFMPVGTQGTVKGVH
                     MTELKEDTKAQIILGNTYHLYLRPGIQILEQAGGLHKFNTWDRPILTDSGGFQVFSLS
                     DNRKLHEEGAEFRSHLDGSKHMFTPEKVMDIERSIGADIIMAFDECCPGDADYNYAKQ
                     SLGLTERWLDRCFARFNSTEPKYGYRQSLFPIVQGCVYTDLRQRAAENVARKGADGNA
                     IGGLAVGEPTDKMYEMIEVVNDILPKDKPRYLMGVGTPINLLEGIERGIDMFDCIMPT
                     RNGRNGQLFTRFGTINMRNKKWENDFSPVDPDGHSYVDTLYSKAYLHHLIKAKEMLGL
                     QIASIHNLAFYLWLVKEARAHIIAGDFTTWKSGMVRQLANRL"
     gene            complement(5331..6929)
                     /locus_tag="ACZPB4_12380"
     CDS             complement(5331..6929)
                     /locus_tag="ACZPB4_12380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HIR1099043.1"
                     /translation="MKKPNYLKGLRVVLAILIFVPILLFFVDFADVLPDNLHTLLHLQ
                     IMPAILGGMAGLVVFQFVLALLFGRIYCSVICPAGVLQDIINRVFCIGKKKKKGVRRF
                     SYHKPMNILRYSILGLTFVLAVFGMIELCTLLDPYSNFGRIANNLFRPVVMWVNNLLA
                     DGLARMDNYTLYHVTISNVTVFGVISALVALLVFILMVVFRGRLFCNTLCPVGTLLSL
                     ISRYSFFRISFDKEACTHCGNCEHTCKAEAIDSKNLTVDTSRCVDCFNCVSSCAKGGL
                     QYRFKPSFKKEAETARAQTDVIQQATAPNSRRTFLSAGATVAVSLPIVSTIAQGMEKG
                     HGKGQHGQGKHGNKWPPIVPPGAISLERFKDVCTGCQICVTQCPSHVLRPTGLEYGFD
                     YMLKPRIAYIDSYCNYECTVCSEVCPTHAIKPLTKEEKATTQVGIATFFINRCIVKTE
                     GTDCGACSEHCPTQAVHMVPYEGTLTIPQVNPDLCIGCGGCESICPVRPMRAIIIKAN
                     EVHKFVEKPKEEEVKKVEIDDFGF"
     gene            complement(6936..7868)
                     /locus_tag="ACZPB4_12385"
     CDS             complement(6936..7868)
                     /locus_tag="ACZPB4_12385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005648783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HIR1099044.1"
                     /translation="MKRRDFLKTSVIASAALSLNFEGLQAALSTNTVAVEKAPDMVAV
                     MGGEPEVMLDKALEALGGIGNFVKKGQKIVIKPNIGWDRSPELAGNTNPKLVKALVKK
                     CLEAGASKVTVFDHTCDNWQKCYETSGIAEAVKEAGGIIMPANDEKYFKEVSIPGGVN
                     LKSAKIHEALIEADAWINVPVLKNHGGAKMTCAMKNYMGIVWDRRFFHQNDLQQCIAD
                     ICTWQKKPVLNIVDAYRIMHQNGPQGKSAADVATLKSLIASPNIVAIDTAALRLFNQV
                     KKLDMAAVGHIGKGEALKLGTTNLDNVTIKRIKI"
     gene            8105..8884
                     /locus_tag="ACZPB4_12390"
     CDS             8105..8884
                     /locus_tag="ACZPB4_12390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099045.1"
                     /translation="MVLYCRVSLNAFVESFRNTSGPDSFFTLPAKGLMHIVPQEEIEY
                     GLSLLRESIGLYEERKGIPVEKSKKAMPFFRQDSRMLVGPEIGMYVIPLYEKPGEPAR
                     SAEPSLVLELDYQSLGELCLFENYSLLSCKYEKEPILNHFTAQLEKEYDTFFFDEEHT
                     GFTPDSRFFSMLCNACLEVKQPSSVGDKEWRLASLQATDEVLYRYEHGNLIPYVPISM
                     PVDCLKRVYLEDFRRQPLLFGTLNGFLKSKGLPAEQLLNLS"
     gene            8888..9769
                     /locus_tag="ACZPB4_12395"
     CDS             8888..9769
                     /locus_tag="ACZPB4_12395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HIR1099046.1"
                     /translation="MKTVSNQELTIRVSEHGAELSSIVANATGKEYLWQADPAFWKRH
                     SPVLFPIVGSVWKAEYRNEGTVYPLSQHGFARDMDFTLIDEAENELRFALESTPDTLR
                     AYPFPFLLEIGYRLEGNKVEVLWRVKNTGDKTMHFQIGAHPAFLYPNYEVDQPDRGYF
                     AFDVKKDLVYRALVEKGCVGDVVRPVPLDADGLLPLNIHTFDIDTFILEDSQIKRVDL
                     LDVEKRPYLSLTFTAPVVGLWSPPTRNAPFVCIEPWYGRCDRVDYTGEYKDRNWVWHL
                     EPGELFDASYTIEIAGA"
     gene            complement(9839..10525)
                     /locus_tag="ACZPB4_12400"
     CDS             complement(9839..10525)
                     /locus_tag="ACZPB4_12400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA];
                     GO_process: GO:0034220 - monoatomic ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
                     /protein_id="HIR1099047.1"
                     /translation="MKYLVIGLGNLGRAIAKDLTRVGNEVIGVDMDLHRVDMLKNDIA
                     GAVALDSTDKEALSTLPLSEMDAIIVTFGKDFGTSVQTVALLKSQDAGKLIVRAISSI
                     HETVIRAIGVSEIITPEKDFSTMYTSQASLGGLFRHWYKVTDTEHLYKIKTPATLVGQ
                     TIKNIDFEENFGIHLVAIERPYEKKNLIGLTQTEYKVISRITEELMIEADDLLILFGK
                     MELLNKIANI"
     gene            complement(10538..12358)
                     /locus_tag="ACZPB4_12405"
     CDS             complement(10538..12358)
                     /locus_tag="ACZPB4_12405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HIR1099048.1"
                     /translation="MNLKNIYFSWLIYWGKMKGLLNGIAEAIILLASLASFFVLIYQF
                     GFVQTPDSVHILERSRPFILLAFFTGITLRYVVRFQEIIQEKMLYLDISIYFLLFAVL
                     SSKIFFKDAIAHSLPYLSFLTKPLFVYVLLLLLSTIHLSRQTFTLMQTRIKPSLLFLL
                     SFVFVILVGAGLLSLPNATTHRIPFIDALFISTTSVCVTGLTTVDVATSFTHIGHIII
                     MILIQIGGIGVMTFTSFFALSFMGKSSFTSKMMLKDMLNEDRTGGLFRVILNILFVTL
                     FIEGIGAYFIYMDVRGSLPGGTQQELFYAMFHAVSAFCNAGISTLSGNMYDPLVADKY
                     NLHFWIAMLIIFGGLGFPIVFNYLKLLHHLLMNGIKILIGKQKHYIHTPRIINVHTYI
                     VVISTLILLITGTAFYLFFEYDNTLGDLPLRGKLANAFLGAVTPRTAGFNVADMATLA
                     PPTLMLTLILMVIGAAPMSTGGGLKVTTVFVALVTTLNAAREKDKVEVRKREIAPFAI
                     RRAFAIIMMYFMWVAIATWVLSYTEKGAPLFSLLFEVVSALSTVGLSIDYTPHLTPIG
                     KIIIISTMLVGRIGVLAFLVSFCKEYTKKDYTYPQENILM"
     gene            12599..13339
                     /locus_tag="ACZPB4_12410"
     CDS             12599..13339
                     /locus_tag="ACZPB4_12410"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016817 - hydrolase activity, acting on
                     acid anhydrides [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0009132 - nucleoside diphosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HIR1099049.1"
                     /translation="MDTQNENREMLSPYVSVDCVLLGINDDKLTVLLAERKSEEGELI
                     GYKLPGSLIYENEDLDDAAYRILNDSTGLKRVQLKQFRCFGSPARTSNRLDVMWLEAT
                     SKVKIGRLITVAYLALCKNSRKTCPADKSESIRWCPIDELPRLPFDHKEIIEAAIQEI
                     RNWVEKEPAIIFDYMPMKFTAFQLRRTYEVIYNREMDVRNFHKKMNSLDYVVPTEDMQ
                     DGVAHRAARYYRFDKVKYNQQRSKFNKI"
     gene            13352..>13800
                     /locus_tag="ACZPB4_12415"
     CDS             13352..>13800
                     /locus_tag="ACZPB4_12415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013547914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY family carbohydrate kinase"
                     /protein_id="HIR1099050.1"
                     /translation="MCLLGCDIGSSSIKVSIVDEETGLTIGADFYPKEEAPIKALRPG
                     WAEQNPEDWWSYVKIAMKGAMSKAKVKGEDIKAIGISYQMHGLVVVDKKMEVLRPSII
                     WCDSRAVPYGERAFKNIGEKRCLSHLLNSPGNFTASKLAWIKEYEPD"
     assembly_gap    13801..13900
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <13901..14426
                     /locus_tag="ACZPB4_12420"
     CDS             <13901..14426
                     /locus_tag="ACZPB4_12420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HIR1099051.1"
                     /translation="EGINYNELNDLAATVPIGCDGLSILPFGNGAERMLQNKQIDCSV
                     HGLNFNIHTKAHMARAAQEGIVFAFKYGMDIMNEMGIDIQVIRAGNANLFLSPIFRDA
                     LAGVTGTVIELYDTNGAVGAAKGAGIGAGIYKNAEEAFASLKKINVIEPDGFKANAYC
                     GAFEIWKERLEQSI"
     gene            14462..15790
                     /gene="xylA"
                     /locus_tag="ACZPB4_12425"
     CDS             14462..15790
                     /gene="xylA"
                     /locus_tag="ACZPB4_12425"
                     /EC_number="5.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009045 - xylose isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0042732 - D-xylose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xylose isomerase"
                     /protein_id="HIR1099052.1"
                     /translation="MSYFKGEKEFFPGIGQIQFEGRESKNPLAFHYYDADKVVMGKTL
                     KDHLRFAMAYWHTLCAEGGDQFGGGTKSFPWNDSADAITRAKYKMDAAFEFMTKCNIP
                     YYCFHDVDVVDEAPTLSEFEKRLQTMVEHAKEHQAATGKKLLWSTANVFSNKRYMNGA
                     ATNPYFPTVACAGTQIKNAIDACIALGGENYVFWGGREGYMSLLNTNMKREKDHLAMM
                     LTMARDYGRKNGFKGTFLIEPKPMEPTKHQYDVDSETVIGFLRHYGLDKDFALNIEVN
                     HATLAGHTFEHELQAAADAGMLCSIDANRGDYQNGWDTDQFPMDIYELAQAWLVILEG
                     GGLTTGGTNFDAKTRRNSTDLEDIFIAHIGGMDAFARALMIAADILEHSDYRKMRAER
                     YASFDAGEGKAFEDGKLTLEDLRTIALRDGEPKQISGKQELYEMIVNLHI"
     gene            15887..17434
                     /gene="xylE"
                     /locus_tag="ACZPB4_12430"
     CDS             15887..17434
                     /gene="xylE"
                     /locus_tag="ACZPB4_12430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-xylose transporter XylE"
                     /protein_id="HIR1099053.1"
                     /translation="MKNNNTYIFALTLVATLGGLLFGYDTAVISGTVESLRKFFIEPQ
                     GFPLDQANALEGFVVSSALIGCILGASFAGWISQRYGRKPTLILAAILFLLSAIGSAW
                     PELFIGMPGSGDHTFMYAFVAYRILGGIGVGLASMVSPMYIAEVAPADRRGNLVAWNQ
                     FAIIFGMLVVYFVNYTIALQGDAAWLNTIGWRWMFASEIIPAVLFLSFLMFVPETPRY
                     LVMRGRTEKALGVLSHLMDQADAGRELEDIRNSFKEKAPSMKPYFRFMGTWLALFLAG
                     YGLLSWAGNTNALEIALLASFCIALLFPIRSFGVLIILVGVLLSGFQQFVGINVVLYY
                     APEIFKTMGAATDAALLQQIVVGAVNLSFTVLAIFTVDKFGRRPLMIIGALVMAVSML
                     ILGTTFYTRSVGMGSLVCMLVYTAGFAMSWGPVCWVLLAEIFPNSIRSTVMSIAVAAQ
                     WIANFLVSWTFPMLDKNQYLTDTFNHGMAYWIYGVMGILAALFIWKFVPETKGKTLEE
                     MEGYWKR"
     gene            complement(17509..>18561)
                     /locus_tag="ACZPB4_12435"
     CDS             complement(17509..>18561)
                     /locus_tag="ACZPB4_12435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1099054.1"
                     /translation="FNKENVLEVRLSMGAALKKGELFKARLLESPAIRDVSFSEFKFV
                     SDESRSFIGYNYKGQHYYMSWLGVSANFPELMDVKMIAGRKFRPTDEAADNTQVVCLL
                     SETAAREIASGVSPEKPDDLSDLVGTSITDNDIPVRIVGIFEDVHYESLYKELRPMGL
                     WTSAKNHYRRSVPERYAYVKIAGGNPRTAIEHIRKVTDELIPGYPADIHFFDTALEEL
                     YSKSGRQGALITALCLMAVFLSLVGVFGLVIFELQGREKEIAVRKVHGSTVRQILWML
                     NSSFLRITLVCFIISIPLAYYGVHIWLRSFAYKTPIYVWVFLVALVIIMTLTVSTVTF
                     QSYRAAMANPASKLGH"
BASE COUNT         4690 a         4151 c         4717 g         4903 t
ORIGIN      
        1 attaaatcga aaggccatgg gagcaaagaa gaattttgtg ttggacacga atgtcatatt
       61 acatgactat aagtgcatcg agaactttca ggaaaatgat atctatctac ccatcgtggt
      121 attagaagag ttggacaagt tcaagaaggg gagtgagcag atcaattata atgcccgtga
      181 gtttgttcgg gagctagact tattgaccag taatgacctg ttcttgaaag gcgcctcact
      241 aggaccggga aaaggtacac tctatatcgt gaccggtgat aagtaccagg agaaaatagc
      301 gcattctttt ccggataaaa ctccagatca ccgtatcttg tcttgtgcgt tgacgatcgc
      361 cgagaagaat ccgaagatca agacaacctt ggtcagcaag gatgtgaacc ttcgtatgaa
      421 ggctcgttct ttgggtattc ccgttgagga ttatatcacg gataaggtcg tgaatgtaga
      481 tattttcgag cgtgcgcaag agacctatga gaatatagac cccgatttga tcgacaagat
      541 ctacagctct ccggaaggcg tggacgcaga ttcgttggat atcaagtcta agctcgaccc
      601 gaacgaatgc tttatcttga aaagcgtacg taatagtgta ttggctcgct acaatccgtt
      661 tacggataag atcaagaagg tggataaagg cacgaacttt ggtatccagc cccgtaatgc
      721 cgagcagagt ttcgctttcg aggtgttgaa cgatccgaat atcaagctgg tggggttgac
      781 cggaaaggcc ggtaccggaa agacgttgtt ggcgttggcc tctgccttga aacaagccgg
      841 cacgtataaa cagatacttt tggcccgtcc gatcgtcgct ttggcgaata aggatctcgg
      901 tttccttccg ggtgacgaga agcaaaaggt cgctccttat atgcaacctc tattcgataa
      961 cctgaacgtg atcaagactc agtttgcccc gggtaatccc gatgtccgta agatcgacga
     1021 tatgcagaag aacaaccagt tggtgatcga ggcgttggcc tttatccggg ggcgtagctt
     1081 gtccgagact tattgtatca tcgatgaggc ccagaacctc acgccgcatg agatcaagac
     1141 gattatcacc cgtgcgggag agggaacgaa gatggtcttc acgggagata tccaacagat
     1201 tgactccccg tatctagacg cccaaagtaa tggcttggcc tatatgatcg acaagatgaa
     1261 aggacaggac ttgttcgccc atatcaactt gataaaaggc gagcgaagcg agttatctga
     1321 attggcgtca gatcttttgt aattaaatat agggaattga agattaaaaa tcaagcttca
     1381 cgaagcgttt attttcaatc ttcaattctt aacgattaat cgtttacact cgggcagaca
     1441 taaatcttcc ggaaactacc tttataggaa ggatctccca tatctttgat ctcattcaga
     1501 tgttgtttaa gatgggcggt ttcgccgtgc ttttgtaatt ccccgtcgtt tttccaagtc
     1561 tcggcgataa agaattcggt gctatcggtg agggactggt acatgccata gtcgatacat
     1621 cccggttcta gcaacgtgct ttccttgcat ttcaagaatg attcctttaa ggcggagaca
     1681 cattcgggtt ttactttccg tttgatattc agtacgactt ccatggattc tttattgctt
     1741 cctccattcg tgcaaccgga tagagcgatt aatacgcagg ccattgagat aaacactttc
     1801 ttcatgatag attgttttta agtatttgat acgacaaaag taatgaattt ttgatctaaa
     1861 cacaggaatc gaacatctga tattaaatta ttgttgttag tggaagttgg aatggatata
     1921 tttgtgataa tattaatagc tatttatgtt aaatttaaaa caagagtcat gagaaagagt
     1981 ttgttgtatg tatttgccgt gatttgcacg atgggttttt ttacggcatg tggtgatgat
     2041 gacgattcaa gttcttccgg taactggcaa gatctgtcga aaacgtacga gggtaagagc
     2101 gttaatctgg taatgggtga agtgacagtc cctgttgacg gtaaatcggt cgtgattgcc
     2161 gcttcctctg cggagaaggc atccgtaacc ttgaacaata tcatccccga aaataagtcg
     2221 gtcgctatcg atgccgcgtt gaaggaagcg gatggcactt atacgtttac cggcgagagt
     2281 acggttggcg attgcgtggt atcagtaaat ggtacggtga aaggggggcg tagcttctgt
     2341 tgtttatact cgtaaattaa cttcttctat cgtaggtaat tggagtttga aagtgggcgt
     2401 ggaagctatc tatgcgaata tcgttaccgg aaattctacg atcgatgatc tcatgcgtat
     2461 gataaagcct gctatcagta acttgatttg gggcaaagta agcgctgtaa atgttaactt
     2521 accggaagat ggaatcttcg atgtttcttg gagacctata ggggcttctg aggataaagg
     2581 aatcggtgag atcacaaaaa tggcaagtat ccaatattgt gtggtagacg ggaaatttat
     2641 ggtggctgtg gataaaaatt atgtgacagt cttgactact ttattacaac aggctgctgg
     2701 tgacaaattg gaggccgctg gtatctctat tgacgagatc atgaagcttt tggttgattt
     2761 aggaggttat tatggtctac ctcttaacat gaaggtggat ggaagtgagg ctacttttta
     2821 tgcggataag gatttaatcg taccggtttt gaccatgata gctcctatct tgaaaccgat
     2881 ggttccggag aattatcagc aaatggtaga tatggtattg caactacttc cgaacgcaaa
     2941 aacgttagag tttggactta atttcacgaa ataattgaaa atcctaggtt gtagagacgg
     3001 agtacacacc gtctctacaa ctggatgaaa tttggcaggg ttataccaat ataggagtta
     3061 atcaattacc ttggtgcttt ctgatataag aatatcgcta taaatgtata aactatattc
     3121 ggtatccaag ctgctacggc aggactcaca taaccattaa tagcgaaggt ggaagtaacc
     3181 gtcataaaca ggatgtaaga aaaactcaac gccaatccga taccaatatt catacccata
     3241 cctcccttta ttttccggga agacaacgac gctccgatag aagtcaagat aaacgccgcc
     3301 atgatcgtgg cgaagcgctt atgatactcg atctggaagg tctgtatatt cccgatacct
     3361 ctttttttct gccggttgat atacgtattt agctcgggcg ttgtcatcgt ctcgcaatca
     3421 ttcacggaaa tcaggaagtc cgagggcacg atggtcaagg tcgtatcctt acgggagcct
     3481 tgggaaatat gttcccgcat gccatcgaaa tcacggatca tataatcgat aacggtccat
     3541 tgataaagcg agtcgtattt gatcgacttg gcggtcagac gggagatcaa ttttttatcc
     3601 tcgaaatgct ccagagagaa acggtatccc atgttcgagc gagcgtcata gctatcgaaa
     3661 taagcgataa cacccggctc gatctccaat tgggcgttct tcacgtaatc caccttcttg
     3721 ttacggatat atttgttctg gaaatcgata cgagtctcat tcgccggggg aatgatgtaa
     3781 gcgttcagga taaacgtcac gatagcgata atcgtagccg agaccgcata aggaagcatt
     3841 aacctacgga aactcatacc gctggcaagc atcgctatga tctccgaacg atccgctagc
     3901 ttcgacgtga aaaagatcac ggcgataaat gtgaacaacg gactgaacaa attggcgaaa
     3961 taggggataa agttcaagta ataatccacg atgatcgctt ttaaggggac atccggattc
     4021 aagaacttat cgatcttctc gtttatatcg aaaacgacgg agatagagat aatcaaggcg
     4081 atagcgaaca cgtacgtgcc cagaaactgc ttgatgatat accaatcgat ccgttttagt
     4141 ttaaatttca tctgtctcgt tttttataac cggttcgcta attgacggac cataccactt
     4201 ttccatgtag taaaatcgcc agcgatgata tgtgccctcg cttctttcac caaccatagg
     4261 tagaaggcga ggttatggat agaagcgatc tgtaagccaa gcatttcttt cgccttgatc
     4321 aagtggtgca gataagcctt gctatataag gtatccacgt aggaatgtcc gtccggatcg
     4381 accggcgaga aatcgttctc ccatttcttg ttacgcatat tgatagtacc gaaacgcgtg
     4441 aaaagttggc cgttgcgccc gttgcgggtt ggcatgatac agtcgaacat atcgatgcct
     4501 cgttcgatcc cttccagtaa attgatcggg gtacctacgc ccatcaagta acgaggttta
     4561 tctttcggta agatatcgtt tacgacctcg atcatctcat acatcttatc ggtaggctcg
     4621 ccaacggcca gtcccccgat agcgtttcca tcggcgcctt ttcgggccac gttctccgcc
     4681 gccctctgcc gcaagtccgt atagacgcat ccctgtacga tcgggaagag actttgccgg
     4741 tagccgtatt tcggctccgt gctgttgaag cgggcgaaac aacgatccag ccaacgctcg
     4801 gtcaggccca gtgattgctt ggcgtaattg tagtcggcat ctcccgggca acactcatcg
     4861 aaggccatga tgatatccgc accgatagag cgttcgatat ccatcacctt ctccggcgtg
     4921 aacatatgct tggagccgtc gagatgcgag cggaactcgg ctccctcttc atgcagctta
     4981 cgattgtcgg aaagagagaa tacctgaaac cccccgctat cggtcaatat cgggcgatcc
     5041 catgtattaa acttatgcaa gcctccggcc tgctccaaga tctggatacc gggacgaaga
     5101 tacagatggt acgtattccc caaaatgatt tgtgccttgg tatcttcctt tagctcggtc
     5161 atatgtacac cctttaccgt accttgcgta cccacgggca taaaaatagg cgtctcgatt
     5221 accccgtgat cggtggtaat caagcccgcc ctagcgttcg atttcgtatc gttatactgt
     5281 aattcaaatg tcatgtatca aaaatttgtg acaaaggtag catttttctc ttagaatccg
     5341 aagtcatcta tttctacctt tttcacctct tcctctttag gcttctccac gaacttgtgt
     5401 acttcgttcg ccttgatgat gatcgctctc atcgggcgta cgggacagat cgattcgcag
     5461 ccgccacaac cgatgcaaag atcggggttt acttgcggga tggtcagcgt gccctcgtaa
     5521 ggaaccatat gcacggcttg ggtagggcag tgctccgaac aagccccgca atccgtcccc
     5581 tccgtcttta cgatacaacg gttgatgaag aaggtggcga tgcccacttg tgtagtcgct
     5641 ttctcttcct tggtaagcgg ctttatagcg tgcgtggggc aaacctccga gcagaccgtg
     5701 cattcgtaat tgcaataact gtcgatgtaa gcgatacggg gtttcaacat ataatcaaag
     5761 ccatactcca atcccgtggg acgtagtaca tgactcgggc attgagtcac gcaaatctgg
     5821 catccggtac atacatcctt gaaacgttct aagctgatcg ctcccggcgg tacgataggg
     5881 ggccatttat tgccgtgctt accttgcccg tgctgccctt tgccatgccc tttttccatt
     5941 ccttgggcaa tggtggatac gatcgggagg gagaccgcga cggtagcccc tgccgagaga
     6001 aatgtacggc ggctgttcgg agcggtagcc tgttggatca cgtccgtttg tgcgcgagct
     6061 gtttcggctt ctttcttgaa ggaaggcttg aaacggtatt gcaatcctcc tttagcgcac
     6121 gaggacacgc agttgaagca atctacgcaa cgggaggtat ctacggtgag gttcttgctg
     6181 tcgatcgcct ccgccttaca agtatgctcg caattaccac aatgcgtaca agcttctttg
     6241 tcaaaggaga tccggaaaaa cgaataccgg gagatcaggc tcaacagcgt tcctaccggg
     6301 caaagcgtat tgcagaacaa ccttccccgg aatacgacca tgaggatgaa tacgagcaac
     6361 gcgaccaaag cggatatcac gccgaatacc gtcacgttgc taatcgtgac gtgataaagc
     6421 gtatagttat ccatccgtgc caatccgtcg gccagcaggt tattgaccca catgacgacc
     6481 ggacggaaca ggttgttcgc tatacggccg aagttactgt acggatctag caacgtacat
     6541 aattcgatca tcccgaaaac agccaatacg aatgtaagcc cgagaattga gtaccgtaag
     6601 atattcatgg gcttatgata gctgaacctg cgtactcctt tctttttctt cttcccgata
     6661 cagaaaaccc ggttgataat atcttgcaat acgcccgccg ggcaaataac cgagcaatag
     6721 atccggccga acaataaagc caatacgaat tggaagacta ccaaccccgc catcccccct
     6781 aaaatagcgg gcatgatctg gagatgcaac aacgtgtgca ggttgtccgg caatacatcg
     6841 gcgaaatcaa cgaagaataa aagtatgggt acgaaaatga ggatcgcgag tacgacccgc
     6901 aatcctttta agtaattagg cttcttcatc ctcgattata tcttaatacg tttgatcgtg
     6961 acattatcca gattcgtcgt acctagcttt aaagcctcgc ctttaccgat atgacctacg
     7021 gcggccatat ccagcttctt cacttggttg aacaggcgaa gggcagcggt gtcgatagcg
     7081 acgatattcg gggaagcgat caaggatttc aaggtagcca catcggcagc gctctttcct
     7141 tgtgggccgt tttggtgcat gatacgataa gcgtccacga tgttcaatac cggtttcttt
     7201 tgccaagtgc aaatatcggc gatgcattgt tgcaaatcat tttgatggaa gaaacggcga
     7261 tcccatacga ttcccatata gttcttcatg gcgcaagtca tcttcgcccc accatggttc
     7321 ttcaatacgg ggacgttgat ccatgcgtcc gcctcgatca gggcctcatg gatcttggcg
     7381 cttttcaggt tcacgccacc cggaatggat acttccttaa aatatttctc atcgttggca
     7441 ggcatgatga tacctccggc ctcttttacg gcctcggcga tcccgcttgt ctcgtagcat
     7501 ttctgccagt tatcgcaggt gtggtcgaat acggtcactt tagaggcgcc ggcctccaag
     7561 cattttttga ccaaggcttt cactaatttg gggttcgtat tacctgccaa ttcaggagag
     7621 cggtcccagc cgatattcgg cttgatcacg atcttttgtc ctttcttcac gaagtttccg
     7681 ataccgccaa gggcttccaa ggctttatct agcatcacct ccggctctcc acccataact
     7741 gctaccatat cgggagcctt ctctacggct acggtgttcg tggaaagggc cgcttgcaga
     7801 ccttcaaaat ttaaggatag agccgcacta gcgatgacac tggtctttaa aaaatcacga
     7861 cgtttcataa ttgtatacta tattggttta tatttgattt acggtacggt cttttttatt
     7921 cgcttgttat tccgaacaaa gataatgatt attttgatat gcgagtcaac tccttttaca
     7981 aagtagaact gctttttact gcaacccggg ttgcagtgat cttgcgtaat aagataattt
     8041 cttgtcggaa ggcatatcgg ttctgataat atttttctac cttgcgaggc aaaaaacaga
     8101 ttgtatggtt ttatattgta gagtatcatt gaacgctttt gtcgaaagct ttcgaaatac
     8161 ctcggggcct gattcctttt tcacgcttcc ggcgaagggg ttgatgcata tcgtgccgca
     8221 ggaggagatc gagtatgggc tttccttgct tagggagtct atcggcttgt atgaggaacg
     8281 caaagggata cctgtggaaa agagcaagaa ggcgatgccc tttttcagac aggacagccg
     8341 gatgctggtg gggccggaga taggcatgta cgtgatccct ttgtatgaga aacccggtga
     8401 gccggcccgg tctgccgagc cttctctggt ccttgagctg gactatcagt cgttgggcga
     8461 gctttgcctg ttcgagaatt attccctgtt gtcctgcaag tatgagaagg agcctatctt
     8521 gaaccatttt acggcacaat tggaaaagga atacgatacc ttcttttttg atgaggagca
     8581 cacgggcttt acgcctgatt cccgcttttt ctcgatgctg tgtaacgcct gtctggaggt
     8641 gaagcagcct tcctcggtgg gggataagga atggcggttg gcctcgctgc aagctacgga
     8701 tgaggtgctc tatcgttatg agcatggaaa cttgatccca tacgttccga tatcgatgcc
     8761 ggtagactgc ctgaaacggg tttatctgga agatttccgg cgacagccct tattattcgg
     8821 gactttgaac ggtttcttga aaagcaaggg acttcccgcc gaacaattac taaacttatc
     8881 ataaggaatg aagacagtat caaatcaaga actaacgatc cgtgtctccg aacatggagc
     8941 ggagttgagt agtatcgtag cgaacgctac gggaaaggag tatctctggc aagcggaccc
     9001 cgctttctgg aaacgtcatt ccccggtatt gttcccgatc gtcgggagcg tatggaaggc
     9061 cgagtatcgg aacgagggaa ccgtgtatcc gctgtcgcag cacggctttg cgcgggatat
     9121 ggattttacg ttgatcgatg aggcggagaa cgagttgcgt ttcgcgctgg aaagtacccc
     9181 ggacacgctg agagcctatc cgttcccttt ccttctggag atcgggtatc gtttggaggg
     9241 caataaggtg gaggtgcttt ggcgtgtgaa gaatacggga gataagacga tgcatttcca
     9301 gatcggcgct catccggctt tcctgtaccc gaattatgag gtggatcaac cggatcgagg
     9361 gtatttcgct ttcgatgtga aaaaagatct cgtataccgt gcgctggtgg agaaagggtg
     9421 cgtaggggat gtggttcgtc cggtaccttt ggatgcggac ggcttgctgc cgttgaatat
     9481 ccatacgttc gatatcgata cgtttatctt ggaggacagc cagattaagc gggtggactt
     9541 attggatgtg gagaaacgcc cgtacctttc gctcaccttt acggctccgg tggtcggttt
     9601 atggtctccg cctacgagaa acgctccgtt tgtctgtatc gaaccttggt atggacgttg
     9661 cgaccgggtg gattatacgg gtgagtataa agaccggaat tgggtatggc atttggaacc
     9721 gggagagctc ttcgatgcct cctatacgat agagatagcg ggggcttgat cgcttcgttg
     9781 atatttgccg taggcagacg acgctgatta tatcgtgatc gtctgcctat gttttgtttt
     9841 agatgttggc tattttattc aatagctcca tcttcccgaa taagatcagc agatcatccg
     9901 cctcgatcat caattcctcg gtgatacggc tgataacctt gtattctgtc tgtgtgagcc
     9961 cgatcaggtt ctttttctcg taaggacgtt cgatcgctac cagatggatg ccgaaattct
    10021 cctcgaaatc gatgttcttg atggtttgcc cgacaagagt ggccggtgtc ttgatcttat
    10081 agagatgttc agtgtcggtt actttatacc aatgccggaa caggccgcct aaagacgctt
    10141 gggaggtgta catcgtagag aaatcctttt ccggggtaat aatctcgctt accccgatcg
    10201 cacggatcac cgtctcatgg atcgaggaga tcgcccgcac gatcagtttg cccgcatcct
    10261 gacttttcaa taaagcgacg gtctgaacgg aagtcccgaa atccttaccg aatgttacga
    10321 taatggcatc catttcactc aatggcaggg tgctcaatgc ctctttgtcc gtagagtcca
    10381 aggcgaccgc ccccgctatg tcgttcttca gcatatcgac acgatgcaga tccatgtcta
    10441 cgccgatcac ctcattgccg acacgtgtca agtctttcgc tatcgcacgt cctaaattcc
    10501 ctaatccgat tactaaatat ttcatgctat cttattttta cattaatata ttttcttgtg
    10561 gatatgtata gtcctttttc gtgtattcct tgcagaaact tacgaggaag gccaataccc
    10621 cgatacgccc gaccagcatc gtgctgataa tgatgatttt cccgataggg gtgaggtgag
    10681 gggtataatc gatgctcaag cctacggtac tcaaggcgga aacaacctcg aacaataggg
    10741 agaacagcgg cgcccctttt tccgtatagg ataataccca cgtagcgatc gccacccaca
    10801 tgaaatacat catgatgata gcgaatgccc ggcggatggc gaatggggcg atctcccgtt
    10861 ttctcacttc cactttatct ttctcgcgtg cggcgttcag ggtcgtaacc aaagctacga
    10921 aaacggtggt cactttcaat ccgccgccgg tggacatagg ggcggctccg attaccataa
    10981 gaatcaacgt cagcattaag gtcggagggg ccaatgtagc catatccgct acgttgaatc
    11041 ctgccgttct aggcgtgacg gcgcctagga acgcatttgc cagtttcccc cgcaggggaa
    11101 ggtcgcccaa ggtattgtca tactcgaaaa agaggtagaa agccgttccg gtaattaaca
    11161 ggatcaaggt agatataaca acaatgtacg tatgtacatt aataatacgg ggcgtatgga
    11221 tataatgctt ttgcttaccg atcaatatct tgataccatt catcagcaag tgatgcaaga
    11281 gtttcaggta attgaagacg atcgggaagc ccaagcctcc gaatataatc agcatggcta
    11341 tccagaaatg gaggttgtac ttatccgcca ctaacggatc gtacatattg ccgctcaagg
    11401 tagagatccc tgcgttacaa aaagcggaca cggcatgaaa cattgcgtag aataattcct
    11461 gctgcgtacc tcccggcagg cttccccgta cgtccatata aataaaatag gcgccgatcc
    11521 cctcgataaa caaggtcacg aaaagaatgt ttaagatgac ccggaacaac cctcccgtcc
    11581 gatcttcgtt caacatatct ttcagcatca tcttgctcgt aaaagaggat ttccccatga
    11641 aggagagggc gaagaaagag gtaaatgtca tgaccccgat accgccgatc tgtattaaaa
    11701 tcatgatgat aatatgcccg atatgcgtga aactagtggc tacgtcgacg gtggttagtc
    11761 cggttacgca taccgaggtc gtggagataa acaaagcgtc gataaacgga atccggtgcg
    11821 tagtggcgtt cggcaacgat agcaacccgg ccccgaccaa tatcacgaac acgaaactga
    11881 gcaagaaaag caacgagggc ttgatccgtg tctgcatcag cgtgaacgtc tgccgggata
    11941 agtgaatcgt gctaagcagc aataataaga catatacgaa gagaggtttc gtaaggaaag
    12001 acaaataagg caaagagtgc gctatggcat ccttgaaaaa tatcttgctg gataatacgg
    12061 cgaataaaag gaaatagatg ctgatatcga gatacaacat tttctcctgt atgatttctt
    12121 ggaacctcac cacgtaccgg agtgttatgc ccgtgaaaaa agctagcagg atgaatgggc
    12181 gggagcgctc taggatatgg acggaatcgg gtgtctgtac aaagccgaat tggtagatca
    12241 atacgaagaa agaggctaag gaggcgagta ggataatcgc ttccgctatc ccgttcaata
    12301 atcccttcat tttaccccaa taaatcagcc aagagaagta tatgtttttt agattcatgt
    12361 ccgatgtttt ataaatataa caaatgtagg aaataaaagt tagaggtacg tgaaagcgcc
    12421 ttcattattt gttctcatac taattgtttt acttacatta tgtgttgtat aacatattgt
    12481 atgatgtacg atactgaaat atcagaaaaa taatcaatta ggagatgcaa aaaagacctt
    12541 ttgtaattgc tttgtttaga aaaatactta tatttgtgca aatctaatta ctgatatcat
    12601 ggatacacaa aacgagaata gagagatgct gtccccttat gtttccgtag actgtgttct
    12661 tctcggcatc aatgatgaca agctcaccgt gctgttggcg gagcgaaaaa gtgaggaagg
    12721 cgagttgatt ggctataaat tacccggcag cttgatctat gagaacgagg atttagatga
    12781 cgccgcctat cggatactga atgattcgac cggcttgaag cgtgtccaat tgaaacaatt
    12841 ccgttgtttc ggttcccccg cccgtacctc gaaccggttg gacgtgatgt ggctggaggc
    12901 gacttccaag gtgaagatcg gacggttgat cacggtcgct tatctcgcct tgtgcaagaa
    12961 tagcaggaag acgtgtccgg ccgataaatc cgagtcgatc cgttggtgcc ctatcgacga
    13021 gcttcctcgc ttgccattcg atcataaaga gattatcgag gctgccatac aggagatccg
    13081 taattgggta gagaaggagc ccgccatcat tttcgactat atgccgatga agttcacggc
    13141 gttccagctt aggcgcacgt acgaggtgat ctataaccgt gagatggacg tgcgcaattt
    13201 tcataagaag atgaattcct tggattacgt ggtacccacg gaggatatgc aagatggggt
    13261 cgcccatcgt gccgcccggt attatcggtt tgataaggtg aaatataatc aacaacgttc
    13321 gaagtttaat aagatataaa accatacgat tatgtgtctg ttaggatgtg acattggaag
    13381 ttcttccatc aaggtctcta tcgtcgatga ggagaccggg ttaacaatag gtgcggattt
    13441 ttatcccaaa gaagaggccc cgatcaaggc gttgcgcccg gggtgggcgg agcaaaatcc
    13501 ggaggattgg tggtcgtacg tgaagatcgc catgaaaggt gccatgagca aggcgaaggt
    13561 gaaaggcgag gatatcaagg cgatcggtat ctcgtaccag atgcatggct tggtggtggt
    13621 ggacaagaag atggaggtgc ttcgtccatc tattatctgg tgcgatagcc gtgccgttcc
    13681 ttatggcgag cgtgcgttta agaatatagg cgagaagcga tgcctttccc acctattgaa
    13741 ctcgccgggt aattttaccg cttccaagct ggcttggatc aaggagtacg agccggatat
    13801 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    13861 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn ggaaggcatc aactataatg
    13921 agttgaatga tttggcggct acggttccca tcggctgcga tggtctttcg atcttgccgt
    13981 tcggaaacgg ggcggagcgt atgttgcaga ataagcagat cgattgctcg gttcatggat
    14041 tgaacttcaa catacatacc aaggcccata tggctagggc ggcgcaagaa ggtatcgtgt
    14101 tcgcctttaa atacggtatg gatatcatga atgagatggg gatcgatatt caggtaatcc
    14161 gtgcggggaa cgcgaacttg ttcttaagcc cgatcttccg ggatgccttg gcgggcgtga
    14221 cgggtacggt gatcgaattg tatgatacga atggcgcggt aggcgcggcc aagggtgccg
    14281 gtattggcgc cggtatctac aagaacgcgg aagaagcgtt cgcttccttg aagaagatca
    14341 acgtgatcga gccggacggt ttcaaggcga atgcttattg cggggcgttc gagatttgga
    14401 aggaacgatt ggaacaatct atttaacggc tgaattattt acatttttaa tatatattat
    14461 tatgagttac tttaaaggag agaaagaatt tttcccggga atcggacaga ttcagtttga
    14521 gggacgtgag tcaaaaaatc cgttggcatt tcattattat gacgcggata aggtagttat
    14581 gggtaaaaca ctaaaggatc atttgcgctt cgctatggct tattggcata ccttatgtgc
    14641 tgagggaggt gatcagtttg gtggtggaac aaaatcattc ccttggaatg acagtgcgga
    14701 cgctatcacc cgtgcgaagt acaagatgga cgccgctttc gagtttatga ccaaatgtaa
    14761 tattccttac tattgcttcc acgacgtgga cgtggtggac gaggctccta cgctaagcga
    14821 gttcgagaaa cgtttgcaga cgatggtgga acatgccaag gagcatcaag ccgctaccgg
    14881 aaagaagctt ctatggtcta ccgcaaacgt cttcagcaat aagcgttata tgaacggcgc
    14941 cgctacgaac ccttatttcc cgaccgtggc atgcgccggc acgcagatca agaacgctat
    15001 cgacgcttgt atcgctttag ggggcgagaa ctacgtgttc tggggcggcc gtgagggtta
    15061 tatgagccta ttgaacacga acatgaaacg agagaaggat catttagcca tgatgttgac
    15121 gatggcccgt gattatggcc gtaagaacgg tttcaagggt acgttcctga tcgagccgaa
    15181 accgatggaa ccgacgaaac atcaatatga cgtggattcg gagaccgtga tcggtttcct
    15241 tcgccattat ggattggaca aggatttcgc cttgaatatc gaggtaaacc acgctacctt
    15301 ggccggacat acattcgagc atgagttgca agccgccgcc gatgccggca tgttgtgcag
    15361 tattgacgcg aaccgtggcg attaccagaa tggttgggat acggatcaat tcccgatgga
    15421 tatctatgag ctggcacagg cttggctggt catccttgag ggaggtggct tgactaccgg
    15481 aggtacgaac ttcgacgcca agacccgccg taattctacg gacttggagg atatcttcat
    15541 cgctcatatc ggtggtatgg acgctttcgc ccgtgccttg atgatcgccg ccgatatcct
    15601 tgagcactca gattaccgca agatgcgtgc cgagcgctac gctagtttcg atgccggtga
    15661 gggcaaggca ttcgaggatg gcaagcttac gctggaagat cttcgtacga tcgctttgcg
    15721 tgacggcgag ccgaaacaga tcagcggtaa gcaggagtta tacgagatga ttgtaaatct
    15781 gcacatctaa ataattgaaa attgagaatt gaaaattgaa aattatcgtg cgtaagccct
    15841 agttttcagc tctcaattct cggtttttca cttataaatc tattccatga aaaataacaa
    15901 cacttatatt ttcgctctaa ccttggttgc taccttggga ggtttactgt tcgggtatga
    15961 cacggcggtg atctccggta cggtggaatc tttgcgtaag tttttcatcg agccgcaagg
    16021 atttccgttg gatcaggcga acgctttgga gggcttcgtg gtaagtagtg cgttgatcgg
    16081 atgtatcctc ggcgcctcgt tcgccgggtg gatcagccag cgttacggca ggaagcctac
    16141 gttgatactg gccgctatcc ttttcttgct ttccgctatc ggctcggctt ggccggagct
    16201 gtttatcggc atgcccggaa gtggcgatca tacgtttatg tatgcgttcg tggcttatcg
    16261 tattctggga ggtatcggtg tggggctggc ctccatggta tcgccgatgt atatcgccga
    16321 ggtggctccg gccgatcgcc gggggaatct ggtggcatgg aaccagtttg ccattatctt
    16381 tggtatgctg gtggtatatt tcgtgaatta tacgatcgcc cttcaaggag atgccgcttg
    16441 gctgaatacg atcggctggc gttggatgtt cgcttccgag attattccgg cggtattgtt
    16501 cctctcgttc ttgatgttcg tgccggagac gcctcgttat ctcgtgatgc gtgggcgtac
    16561 ggagaaggcg ttgggggtct tgagccattt gatggatcag gcggacgctg gccgtgagct
    16621 ggaggatata cggaatagtt tcaaggagaa agctccgtcg atgaagcctt acttccggtt
    16681 tatggggact tggctggcgc tgttcttggc cggctacggg ttgttgtcgt gggcaggtaa
    16741 tacgaatgcg ttggagatcg ccttgttggc tagtttctgt atcgccttgc tgttcccgat
    16801 ccggtcgttt ggcgtgctga tcatcttggt gggcgtgttg ctctccggtt tccagcaatt
    16861 cgtggggatc aacgtggtgc tttactatgc cccggagatc ttcaagacga tgggagcggc
    16921 cacggacgcc gcccttttgc aacagatcgt ggtaggggcg gtgaacctgt cgtttaccgt
    16981 attggctatt ttcacggtgg ataagttcgg acgccgtccg ttgatgatta tcggggcgct
    17041 cgtcatggcg gtatctatgt tgatcttggg aactactttc tatacgcgtt cggtgggtat
    17101 gggatcattg gtctgcatgc tggtttatac ggcgggattc gctatgtcgt ggggcccggt
    17161 ctgctgggtg ctgctggccg agatcttccc gaactcgatc cgctccacgg tgatgagtat
    17221 cgccgtagcg gcgcagtgga ttgccaactt cttggtatca tggacattcc caatgctgga
    17281 taagaatcaa tacttgaccg atacgttcaa tcacggtatg gcctattgga tctatggcgt
    17341 gatgggtata ttggcggcgt tgttcatctg gaaatttgtc cccgagacga aaggaaagac
    17401 gctggaggag atggaaggtt attggaaacg gtaaccaaac ctgagacaag ataatatatg
    17461 agtaaaaaag gacggatcaa tctacccgtc cttttttcgt aatgaacctt aatgtcccaa
    17521 tttagacgcc gggttcgcca tcgccgcccg atagctctgg aaagtaaccg tagatacggt
    17581 cagtgtcatt atgattacca aagccactaa aaatacccat acgtagatcg gtgttttata
    17641 agcgaagctt cgtaaccaaa tatgcacccc atagtaagca agcgggatcg agataataaa
    17701 acagacgagc gtgatccgga ggaaagacga gttcagcatc caaaggattt gccggaccgt
    17761 ggacccatgt actttccgca cggctatctc cttttcccgt ccctgtaact caaagataac
    17821 cagtccgaat actcccacga gggataaaaa gacggccatc aggcaaaggg cggtaatcag
    17881 cgctccctgc cgcccacttt tactgtaaag ctcctccagc gccgtatcaa agaaatggat
    17941 atcggccgga taacccggga tcaattcatc cgttaccttc cggatatgct cgatagccgt
    18001 ccggggattt ccgccggcga tcttgacata agcgtatctt tccggcaccg aacggcggta
    18061 atgattctta gccgaggtcc aaagtcccat cgggcgtaac tctttataca gggattcata
    18121 atggacatcc tcaaagatac cgacaatccg taccggtata tcattatccg tgatgcttgt
    18181 tcctaccaag tccgataggt cgtccggttt ctcgggggaa acacccgagg cgatctctct
    18241 cgctgccgtc tcgctaagga ggcaaacgac ctgcgtgtta tccgccgcct catccgtcgg
    18301 ccggaacttc cttccggcga tcatctttac atccattagc tccgggaaat tggcggatac
    18361 tcccagccag ctcatataat aatgttggcc tttgtaatta tacccgatga aagaacgtga
    18421 ttcgtccgag acaaatttga actcgctaaa ggaaacatca cggatagcgg ggctttccaa
    18481 gagacgtgcc ttgaacaatt cgcccttttt caaggccgcc cccatgctta gtcttacctc
    18541 cagtacgttt tctttgttaa a
//
LOCUS       DBMDTB010000081        18549 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_984_length_18549_cov_11.979022, whole genome shotgun sequence.
ACCESSION   DBMDTB010000081 DBMDTB010000000
VERSION     DBMDTB010000081.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 18549)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 18549)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18549
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_984_length_18549_cov_11.979022"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..1464)
                     /locus_tag="ACZPB4_12440"
     CDS             complement(<1..1464)
                     /locus_tag="ACZPB4_12440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099055.1"
                     /translation="MKNNLYVFFLFFITGLMSCSHHSGLYEHAEKIMSQHPDSVLTLL
                     STIQDVNDLSEKDRAMYYLLLTEAEDKTYKKHESDSLIAIATEYFDKTDDVKRKAKAW
                     YYRGRVVDDLKDAPRAQDYYLKALQNEMEITDYAFLGRLYNSIGMLYTYQEVYEKAVL
                     YQKKALYCFEALYDSIGQSYVLRDIGRNMTALNKMDSAIFYYEKALYFCDQKSKSSVY
                     RELANLYLDIDNYSKGLEYIEKVLSSPLKKSMLDSFYFVLGKYYQKTNQVDSAYYYLG
                     YSSNSSRLQTQAAAYYHLAQLERFRENWKGYANNQIRYEVLRDSVNQTKKTESIRRIE
                     KIYDYHKTEAKLLQSEVLLNKLKVKNLTVTLILIISIVVIVVISVLGYVQMKKKKLRL
                     QEHRELLQALEKKHQADLTRIEENEKLIRELEEMLQKSSRAYNEKEKELMALQKMKLE
                     TENQNLRYVKTENRFLIESFQMSDIYYKFHMKEEWRPK"
     gene            complement(1691..2476)
                     /locus_tag="ACZPB4_12445"
     CDS             complement(1691..2476)
                     /locus_tag="ACZPB4_12445"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008934 - inositol monophosphate
                     1-phosphatase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006020 - inositol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HIR1099056.1"
                     /translation="MELDLAYLCKEVREIARASATFLKEERRKFDRNLVEEKSAHNYV
                     SYVDKESERQIIEALSTLLPEAGFIAEEGSGSLTDEEYCWVIDPLDGTSNYIHDIAPY
                     CVSIALRNRKELLLGVVYEVCRDECFYAVKGGKAYLDGNEIHVSDVSVLDNAFIALGF
                     PYNSDAYRPVAAHLVDRLYGFAGGTRLMGSAAAELCYVAAGRFDARIEAFLGPWDVAA
                     GALILLQAGGKISDFNGGENWASGEQVVASNGKVHSLVLSLLP"
     gene            2654..3328
                     /locus_tag="ACZPB4_12450"
     CDS             2654..3328
                     /locus_tag="ACZPB4_12450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HIR1099057.1"
                     /translation="MKTIHYLSIIILSFSSQILLAQNDTLVGVLRDISDKIIKRYPVT
                     LGSQNPITVKTNKHGVFTIPGANLNDTLFVTIKKTRNVVKVPVNGYNYITITLENSTF
                     NAKRSFEPDEALKEIMERERNKIVSSSVMNKEEIQKTGCRDLYCLLRRMSGITFADGS
                     VRIRASVSLNSPSDPLVVVDGIPMDLSVLNTIPVEDVSELKVLKDAGEYGVRGANGAI
                     VIKTGK"
     gene            3358..7974
                     /locus_tag="ACZPB4_12455"
     CDS             3358..7974
                     /locus_tag="ACZPB4_12455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translocation/assembly module TamB
                     domain-containing protein"
                     /protein_id="HIR1099058.1"
                     /translation="MRVWIKRIGVICLIPIALVLLLSILLYIPPFQNFAVRKATEYAG
                     KVTGMQIGIEQIRLSFPLDLTVKGVEVVNPPADTLLSLQSLTVRVRALPLLRKQVLVE
                     AIDLRNVKVNTGTMIEGMEIKGFLGKLYLHADRIDLSEEKATFNTIDLFDTAITLLLN
                     DSTSKEDTTSTPLNWVLKLDKISLDRVAFALQMPSDSLRLTAFVNKAGLNNGLVDIGA
                     EQYKARNFDITNSTFAYDGNYATPEQGLDFSHISLTNLNTSIDSILYQGKEINAHIKE
                     FFVEERSGLKVSALAGNVRSDHEQIDVPDLLLQTPNSEVRLTATIPWSSLEDHPQGSM
                     KALLNASLGKEDLLIAAGSLPEDFKKAYPDKPLAITAGVEGNLSSIRITQGDIMLPGA
                     FQMNVTGSMESVTDSIRRTGEIQLKARSGNLDFLLAMLPASQRDQFAIPAGIQLKGEA
                     TVANQEYRTELVLTQDKGKVGLTARYNPVQLAYEANLRIDSLEPTHFMPKDSLFWLTA
                     SVKAEGRGTDPFSERTWAKLDGKISDIRYGASSVSDVSIDGSLEKNLLKVDLLSKYPL
                     AKMDVSLNATLHKHEVKAMLIADVENMDLQGMHLMANPFATSFQLFAEVESNLDEDNT
                     IDVTLGNWEVVTPKQSFKPKTLTLHARTDIDTTRVSFHAGDLGIILTGNDCIHHITDK
                     LTKVSNDITLQLERDSTVNLEILRPLLPDMYLEVRAGQDNPIYNYLQTYYVDFKSIAM
                     NAYTSPETGIRMDASIYDLARDTMQIDTIRAEMHQDSLGLLYSAQVIKNKYRQQQPFS
                     AGLDGQIRYGFGDARLYFKDGKGETGLLLGIRADKIQNGVKFHLFPDDPIIAFRPFKL
                     NPDNYVVVRSMKDIEANLRLSGDNNAALWIHSQAESDEMEEVHAELNQIDLGIISNAF
                     SYIPPMKGILNADFQYAPSDSAFMVVADMNIDDLYYENERVGELMFNAVYLPLEQGNH
                     QVDMHLFRDRKEVSAITALYQMGETDHISGTVEFMHFPLDIANPFIPDDMAKMGGDLD
                     GTLAISGQSDKPMAEGYLILDTASVYVGAAGSTFRFDDKKIEIKNNRILFNQYGIYAY
                     NKNPFIINGEVDFNNLSRMTANLKLTANNLQLLNVKKNEESLVYGKLFVNLNSTVRGP
                     LDALTMRGDLQLLGGTNITYVLKDSPLTVQDRMSDMVTFTSFTDTLRRRMPRKPPLPM
                     GGMDMLMTIHIDPAVQANVDLSPDQSNHINLEGGGDLSFQYTPQGDMFLNGRYTLSGG
                     TIKYSIPVIPLKEFNVQEGSYVQWTGNPMDPTLNLTATERVRTSVTLTGQSSPRLVNF
                     DVGIELTQQLENLGLQFTLTAPEDMAMQEELTSKGPEERAKLAVSMLVTGMYLGGGGG
                     GGKVNVNMGDALTSFLQSEINNIAGSALKSVDISFGMETYDDNGDAGGGTRTDYSFRF
                     AKRFYNDRIRVVLGGRISTGENINNGQAQPFIDNVSVEYRLDSSGSRYVKLFHDKNYE
                     SLLEGEITETGAGIVLRKKMMHLRELFNFKKTKVKPVKEETEKE"
     gene            7977..10427
                     /gene="tamL"
                     /locus_tag="ACZPB4_12460"
     CDS             7977..10427
                     /gene="tamL"
                     /locus_tag="ACZPB4_12460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translocation and assembly module lipoprotein
                     TamL"
                     /protein_id="HIR1099059.1"
                     /translation="MKNVLIYFRKDALLEQGNMPSQSRETCLPKAGKDTSPGRGGVST
                     QRAILSSLALLGLLAFLLTSCSTTKNLPEGAVLYTGIKKIEVKNEDKTKPGEAALEEV
                     EAALAYPPNNALLGSSSIRVPFPFGLWVYNAFVNKKGKVGKWIFNKLASKPVLITTVN
                     PEVRVKVARNLLNEYGYFNGETSFEVVPDPKNPRKAKLEYSVTMNDPYTLDSIQYVHI
                     RHRADSLIDATIGDRILHKGENFNVVQLQAERERISSLLRNNGYYYFRPDFITYQADT
                     LLNPGKVALRVAPKESLPPSALRPWKLGDISVWLNGYQNETPTDSIRYKDLTIHYEGK
                     LRVRPSVIYNRLYFKPGELYNQRAQERTQTALSRLGIFRYAELQYSPRDTMRRQDTLD
                     LRINTVYDLPLDGELELNVTAKSNDQVGPGAIFSVTKRNVFGGGETFGVKLRGSYEWQ
                     TGNKLDGSNSKINSYELGLTTTLTFPRVLFPTFSKRDMNFPASTTFRLYADQMNRARF
                     FKLLAFGGDASYEFQPTATSHHSITPFKLTFNLLQHTTHEFDSITNVNKALKKSLQNQ
                     FIPAMNYTYTYDDSPITSRRNHLWWQASVTQAGLVLDGIYALAGKKFNKEDKELLGNP
                     FAQFIKGTAEIRYNYALGHKQYLVGRLMAGAIYSYGNARTSPYNEQFYIGGANSIRAF
                     TIRSIGPGRYYQNSDNNKYAYIDRTGDLKFEANLEYRFPILGDLHGATFLDSGNIWLI
                     RNDPDRPGGQLKWGSFLKDLALGTGFGLRYDLTFIVIRFDVGIGLHLPYDTGKKGYYN
                     IPKFKDGMGYHFAIGYPF"
     gene            10557..11828
                     /locus_tag="ACZPB4_12465"
     CDS             10557..11828
                     /locus_tag="ACZPB4_12465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099060.1"
                     /translation="MKKIFYLMLVALTVGMFTACDDDDENTPQINNPEPKEQWGKTLR
                     GDNQTLLAFPDIYADYWEYTYSYKDNPNIGLRLTGKFPKSRFFNFTVYNDETQIDVSS
                     IEDVNIQPDDSSINPYVKETDDYGANGYTIYIIPANTPASARASMKNVCEFPEDVNMV
                     SIFMRLYLAKQYSGDEYGGVDMPAIQAFNVTTGEEVDFPKREVCNIHESLNLPPMDFS
                     ADLPQLPFMRAPLSLMYPNSPAEYLFARIKLNEGEVATFRFIPPTAPKSVSEYATADV
                     RYWSICLGSAETYSYASIYDKEMPKVDKEGFVTFIIADANSAKLPDLQAKAEANDGTY
                     ILTWNRKEQGDGILALYRNMVINENYPHSMRKLMESVPLAAAGGDMSGFNPMKMIAML
                     AMGNWGPQGYKFSEDDFLSDSFNYANIRRMK"
     gene            complement(11934..12830)
                     /gene="rocF"
                     /locus_tag="ACZPB4_12470"
     CDS             complement(11934..12830)
                     /gene="rocF"
                     /locus_tag="ACZPB4_12470"
                     /EC_number="3.5.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004053 - arginase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0000050 - urea cycle [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginase"
                     /protein_id="HIR1099061.1"
                     /translation="MKINVIGVPLNLGCDRAGVERAPNHLRERGLMGVIRKNGHKAFD
                     LGNLYVPPVSEADKFVRGNSMKYLDAIVEVNTNLAELVYDTLRGGAFPLVIGGDHSLG
                     LGSASGVGKCYDDFGIIWLDAHGDINTSETSPSGNIHGMPLSALMGMGSEELVNIYAP
                     GNKVNPQNVFLVGTRSLDEGEWDLIEREKLSVYTMETIHLKGIGFVAEDIKRKLKERK
                     IRNVHFSIDVDSIDPRFAPGTGTRVCEGLMPDEFNNFVDHMLSTNLVKSMDLVELNPE
                     LDVNEQTTNLCLQIIDYITARL"
     gene            complement(12834..14042)
                     /gene="rocD"
                     /locus_tag="ACZPB4_12475"
     CDS             complement(12834..14042)
                     /gene="rocD"
                     /locus_tag="ACZPB4_12475"
                     /EC_number="2.6.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004587 - ornithine aminotransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine--oxo-acid transaminase"
                     /protein_id="HIR1099062.1"
                     /translation="MKPEDYITREEKYGAHNYHPLPVVLRRGEGVFVWDVEGKRYFDF
                     LSGYSALSQGHCHPKIVKALMEQAERLTLVSRAFHADILGEYMEFTCKFFGYDKLLPM
                     NTGAEAVETALKLCRRWGYRRKGVAPERAKIVVCSENFHGRTITIISMSTDPSSYADF
                     GPYTPGFIKIPYNNVDALAEALKDPDVVGFLVEPIQGEAGVVVPDDGYLRACYDLCHQ
                     HNVLFIADEIQTGIGRTGKLLACDYEGIRPDILILGKALSGGVSPVSAVLADDEIMLT
                     IAPGEHGSTYGGNPLAAKVAIAALEVVRDEHLSENAFKMGELFRGEMERINNPMIKKV
                     RGKGLLNAVVTEPKDGKTAWDICLALKENGLIAKPTHDHIIRFTPPLVITEEQMMEAI
                     GIIRDTFAKF"
     gene            complement(14263..15426)
                     /locus_tag="ACZPB4_12480"
     CDS             complement(14263..15426)
                     /locus_tag="ACZPB4_12480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HIR1099063.1"
                     /translation="MDTETVSPNFDDIRPLNNSEVKDAIEKLVANEDFERALRYIKPN
                     LNWEEFSVAMRACKTKEEFKSTLAYDAVMTVAKNTTFSLTISGRSRLPKDKAACTFIS
                     NHRDIVLDASFLNVMLYDVGYGMTQVAIGDNLLIRPWIETLVRLNNSFIVKRGVSVRQ
                     MLEVSKTLSAYIHHVIKNVNESVWIAQREGRAKDSDDRTQGSVLKMLSIGGDKDNLLL
                     NLMDLNIVPVAISYEFDPCDFLKAKEFQMKRDDPDFVKCQRDDLLSMETGILNNKGRV
                     HFTITSPINDSLAKLDKDMEKNELVSAIASVIDREIYKNYRFYSCNYVAYDWLNGTRR
                     FHEHYGPKDKKQFEEYIQGQLDKIVLPNKDEAFLRKKLLEMYSNPLKNYLTTL"
     gene            complement(15433..16425)
                     /locus_tag="ACZPB4_12485"
     CDS             complement(15433..16425)
                     /locus_tag="ACZPB4_12485"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HIR1099064.1"
                     /translation="MKKNIAIVAGGDSSEIVISLKSADGIYSFIDKDKYNLYIAIVKR
                     DEWAVILPSGEHTPIDKNDFSFKENGVTRHFDFAYITIHGTPGEDGRLQGYFDMIGMP
                     YSSCGMLVSALTFNKYVCNHYLKDFGVKIAASIHLFKGETITDEEVVTRLGLPIFVKP
                     NDGGSSFGVTKVKELSAIQPAIAKAFGEGREVILESFIDGTEVTCGCYKVEGKEVVFP
                     LTEVVTDNEFFDFDAKYNGQVDEITPARISAELTELIQRKTSRIYDILGAKGLIRVDY
                     IIPADGEPVLLEINTTPGMTATSFIPQQVRAAGLDIKDVMTDIIEDELKNRKTK"
     gene            complement(16428..17507)
                     /locus_tag="ACZPB4_12490"
     CDS             complement(16428..17507)
                     /locus_tag="ACZPB4_12490"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HIR1099065.1"
                     /translation="MDEFLDDMDDEQVDDLLMPEEDETSSSQMYEHFRFVADKGQSLL
                     RVDKFLVDRMMGATRNRIQLAAEAGCILVNDKPVKSNYRVKPLDVVSVVMDRPRRELE
                     IIPEDIPLNIVYEDDDLLVVNKPAGLVVHPGHGNYTGTLVNALAYYLKDDPYYDPSDP
                     RLGLVHRIDKDTSGLLVVAKRPEAKSNLSLQFFNKTTKRKYRALVWGIVQEDEGRIEG
                     NIGRDPRDRMQMTVFPEGDQGKTAVTHYTVLERLGYVSLVECRLETGRTHQIRVHMKY
                     IGHTLFNDERYGGHDILKGTTFTKYKQFVQNCFAICPRQALHAKTLGFVHPTTGEEMF
                     FDSEIPSDMQQLIDRWRVYANTKEL"
     gene            complement(17512..18138)
                     /locus_tag="ACZPB4_12495"
     CDS             complement(17512..18138)
                     /locus_tag="ACZPB4_12495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PASTA domain-containing protein"
                     /protein_id="HIR1099066.1"
                     /translation="MSNFFVKLIKNPFVINLLLVIVVSCGVVYGVLAWLDSYTRHNQA
                     VVVPDVKGMKLEDAAEFFGNNKLRYNVIDSVFSKDVAPGSIVELVPGVGSKVKEGRIV
                     FVTINALTSQMAVIPEVEDLSFRQAYALLRARGFSSVEIEYVPGDYKDLAMGVELNGR
                     TLLKGEHVPLTAHLVLKVSSGDPNMLPDSLALDSIPVEPLDSDIENWF"
     gene            complement(18289..18441)
                     /gene="rpmH"
                     /locus_tag="ACZPB4_12500"
     CDS             complement(18289..18441)
                     /gene="rpmH"
                     /locus_tag="ACZPB4_12500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005633099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HIR1099067.1"
                     /translation="MKRTFQPSNRKRKNKHGFRSRMATANGRRVLASRRAKGRAKLTV
                     SDEYNG"
BASE COUNT         5150 a         4849 c         3868 g         4682 t
ORIGIN      
        1 tttaggtctc cattcttctt tcatatggaa tttataataa atatcagaca tctgaaaact
       61 ctctattaaa aaccgatttt cagttttaac atatcttaaa ttctgatttt cagtttccaa
      121 cttcattttt tgaagagcca tcaactcttt ctctttttca ttgtaagctc tagatgattt
      181 ttgcaacatt tcttctaatt ccctaataag tttttcattt tcctcaatgc gagtcagatc
      241 tgcttggtgt tttttttcta gagcctgtaa tagctcccta tgctcttgta aacgcaactt
      301 tttctttttc atctgcacat atcctaaaac tgatatcacg acaatcacga caatacttat
      361 aattaaaatt aaagtcacag ttaaattctt tactttcaac ttattcaaca agacttcaga
      421 ttgtaatagt ttagcttctg ttttatgata atcatatatt ttctctattc gtcttattga
      481 ttccgttttc tttgtttggt ttacagaatc tcttaaaact tcatatctaa tctgattatt
      541 cgcataacct ttccaatttt cccggaatct ctccaactga gctaaatgat aataagctgc
      601 agcttgtgtt tgtaacctag agctgttgct actatatcct aaataataat acgctgaatc
      661 aacttggtta gttttttgat aatatttccc taacacaaaa taaaaagaat ctaacattga
      721 cttttttaaa ggagaactta agaccttctc aatatactct agcccttttg aataattatc
      781 aatatctaaa tacagattag ccaattctct atatacagag gatttactct tctgatcaca
      841 aaagtataac gccttttcat aataaaaaat agcactatcc attttattta aagctgtcat
      901 gttccgtcca atatctctca gtacataaga ttgcccaatc gaatcataaa gggcttcgaa
      961 acaatataaa gctttttttt ggtaaagaac cgctttttca tatacttctt gataggtata
     1021 aagcatccct atactattat ataaacgtcc aagaaaagca taatcagtaa tctccatctc
     1081 attttgtaaa gcttttaaat aataatcctg cgcccgtgga gcatctttca aatcatcaac
     1141 aacacgtcct ctataatacc aagcttttgc ttttcttttc acatcatctg tcttatcaaa
     1201 atattctgta gctattgcaa ttaatgagtc tgactcgtgc ttcttataag ttttatcttc
     1261 cgcttctgtc aaaagtaggt agtacatagc acgatccttt tctgaaagat catttacatc
     1321 ttgtattgtt gatagcaatg ttaaaacgct atcgggatgt tgggacatta tcttttccgc
     1381 atgttcatat agacctgagt gatggctaca tgacattagt ccagtaataa agaacagaaa
     1441 aaagacgtat agattgtttt tcatactctg taacattttt attttccaca aatgtaagta
     1501 aaatctctaa tcctaaaagt cttgattttt actgaattag acacatacaa ggatttacgg
     1561 gtatttgtat tcctccatct gttttgaaaa tcaaaacgga tcaaacaccc cgcaaataag
     1621 aagtaagttt aaactctttt accttttaaa tacacacaga agcactagaa tacgcaggat
     1681 tactctagta ttagggcaac aaagacaaca caagagagtg aaccttgcca ttgctggcaa
     1741 ctacctgttc acccgaagcc cagttctctc ctccattgaa atctgatatt tttcctccgg
     1801 cctgcaataa aatcaaggca ccagcagcta cgtcccaagg gcctaaaaag gcctctatac
     1861 gggcatcaaa acgtcctgct gccacataac acagttcagc ggcggcagat cccatcaaac
     1921 gggtacctcc cgcaaaacca tacaacctat caaccaaatg agcggctacc ggacgataag
     1981 catcagagtt ataagggaaa cccaacgcaa tgaaagcgtt atccagtact gagacatccg
     2041 atacatgtat ctcattccca tccaagtaag ccttaccacc tttcactgca taaaaacact
     2101 cgtccctaca cacctcatag actactccta acaataactc cttccgattt cttaaagcga
     2161 tactcacgca ataaggcgcg atatcatgaa tatagtttga agtaccgtcc aatggatcaa
     2221 ttacccaaca atattcctca tcggtcaaac ttccagagcc ttcctccgcg ataaaaccag
     2281 cctcgggtag caaagtagac aaagcctcta tgatctgtcg ttccgattct ttatccacat
     2341 aagatacata gttatgagca cttttttcct ctactaagtt ccggtcaaac tttcggcgtt
     2401 cttcttttaa gaatgtcgca gaagcacgag ctatttctcg aacctcctta cacaaatagg
     2461 ctaaatctaa ttccataccg ttcattttat tttggcaaat gtaatgattt ccatttatag
     2521 taatctcatt ttagcgacaa atgagaccac atagaaacgt aaaaataata cctattacga
     2581 atttgcccta aaactctgcc tttaagaaat attatattat ctttgtgtta tgttcagcta
     2641 aaaagattta gctatgaaaa caatacatta tctttcaatc atcatcttat cattcagcag
     2701 tcaaatactt ttggcacaga atgatacttt agtcggtgta ttgcgtgaca tcagcgataa
     2761 aataatcaaa cgctatccgg tcacgctagg cagtcagaat ccgatcaccg tgaaaacgaa
     2821 caaacatggc gtattcacca tcccgggggc taacctgaat gataccttgt tcgtcactat
     2881 taagaaaaca agaaatgtag tcaaagtccc agtcaacgga tacaattata taaccattac
     2941 tttagagaat agcacattca acgcaaagcg tagttttgaa ccggatgagg ccctgaaaga
     3001 aattatggaa agggaacgaa acaaaatagt aagctcaagc gttatgaata aagaagagat
     3061 acagaaaacc ggatgccggg atctctattg cctactacga aggatgagtg gcataacatt
     3121 cgccgatggt tccgtacgca tccgtgcgag tgtttcccta aacagtccta gtgacccgct
     3181 agtagtggta gacggtatac cgatggacct atctgttcta aacacgattc ccgtcgaaga
     3241 tgtctcggaa ttaaaagtat tgaaagacgc cggtgaatac ggggtaagag gcgcaaacgg
     3301 agcgatcgtc ataaaaacag gcaaataaac aaataagaaa aagagaaacg tatcaacatg
     3361 agagtatgga ttaaacggat aggagtgata tgcctaatac cgatcgcatt ggtattgtta
     3421 ctctctatat tactatatat acctcctttc caaaacttcg cggtacggaa agcgaccgaa
     3481 tacgcaggaa aagtgactgg tatgcaaatc gggatcgagc agattaggct atctttcccg
     3541 ttagacctta cggttaaggg tgtcgaggtc gtaaatcctc ccgccgatac cttgttgagt
     3601 ttacagagct tgacggtacg ggttcgtgcc cttcctcttt tgcggaagca agtattggta
     3661 gaggcgatcg acctccggaa cgtaaaggtt aacaccggga ctatgattga aggtatggaa
     3721 atcaaaggat tcttgggaaa gctttacctg cacgccgatc gtatagacct gtccgaggag
     3781 aaagctacat ttaataccat agatttattc gataccgcca ttacccttct attaaatgat
     3841 tcaacctcga aagaagacac gacttccaca cctctgaact gggtactcaa gctggataaa
     3901 atcagtttgg accgggtagc cttcgcccta caaatgccct cggattcctt acgccttacg
     3961 gctttcgtta ataaagccgg gctaaataac ggcctcgtag atattggagc ggaacaatat
     4021 aaggcgagaa actttgacat aacgaattct acattcgctt atgacgggaa ttacgcgaca
     4081 cccgagcaag gactcgattt ctcccatatt agtttaacga acctgaacac ttctatcgat
     4141 tccatcttat atcaaggaaa agaaataaac gcccacatca aggaattctt cgtggaagaa
     4201 cgttccggcc tcaaggtttc ggcattggca ggaaatgtcc ggagtgacca tgaacagata
     4261 gacgtaccgg acctacttct ccagacacca aattccgaag tgagattgac agcgactatc
     4321 ccttggagct ccctcgagga ccacccacaa ggtagcatga aagccctgtt aaacgcctcg
     4381 ttggggaaag aagatttatt gatagcggca ggttccctac cggaggattt caagaaagcc
     4441 tatccggaca agcctctcgc tattacggct ggcgtagaag gcaacctctc cagtatacgt
     4501 atcacacaag gcgatatcat gctgccggga gcgtttcaga tgaacgtcac gggtagcatg
     4561 gagtccgtga cggatagcat ccggcgaacc ggtgagattc agttaaaggc tcgatccggt
     4621 aatctggact ttttgctggc gatgcttccc gcctcccaac gggatcaatt tgccattccg
     4681 gcaggaattc agttgaaggg ggaagctaca gtcgcaaatc aagaataccg caccgagctt
     4741 gttcttaccc aagataaagg caaagtaggt ctgaccgccc gctataatcc ggtgcaactg
     4801 gcttatgagg ctaatttacg gatagacagt ctggaaccta cccatttcat gcccaaagac
     4861 tctctatttt ggctgaccgc ctctgttaaa gcagaaggcc ggggcacaga ccctttctct
     4921 gaacgtacat gggccaaact ggacggtaag atatcggata tacgctacgg cgcctcatcg
     4981 gtatcagacg tatccatcga tggctctctg gaaaagaact tactgaaagt ggatctgctt
     5041 agcaaatacc cgttggcgaa aatggatgtc tccttaaacg cgaccctcca caagcacgag
     5101 gtgaaggcga tgttgatagc ggatgtggag aacatggatt tacagggtat gcacttaatg
     5161 gcaaatccct tcgccacctc tttccagctc ttcgcagagg tagaaagtaa tctggatgaa
     5221 gataacacga tcgacgttac gttaggaaac tgggaggtcg tcaccccaaa acaaagtttc
     5281 aagccgaaaa cgctgacctt gcatgcccgg acggatatcg ataccacccg tgtgtctttc
     5341 cacgccgggg atttagggat catcctcacg ggtaatgatt gcatacacca catcacggat
     5401 aagttgacta aggtatcgaa cgatatcacc ctccaattgg aacgggactc gactgtcaat
     5461 ctggagatcc ttcgcccgct cctccccgat atgtaccttg aggtacgggc aggacaggac
     5521 aatccgatct acaactatct ccaaacctat tacgtagatt tcaagagcat cgccatgaac
     5581 gcctatacct caccggaaac gggtatacgc atggatgcct ccatttacga tctggcacgg
     5641 gatacgatgc agatcgatac catccgggca gagatgcacc aagattcgct cggattactc
     5701 tatagcgccc aagtgatcaa gaataaatac aggcagcaac aacctttcag cgccgggctg
     5761 gacgggcaaa tacgttatgg cttcggcgac gcccgccttt atttcaagga cgggaaaggc
     5821 gagaccggct tgttgctcgg aatccgggcc gataagatac agaacggggt caagttccat
     5881 ctcttccccg atgacccgat catagcgttc cgccctttca agctgaaccc ggataattac
     5941 gtcgtggtac gcagcatgaa ggatatcgag gcgaacctgc gactcagcgg agataataac
     6001 gccgccttgt ggatacactc ccaagcggaa agtgacgaga tggaggaagt ccacgccgag
     6061 ttgaaccaga tcgaccttgg gattatctcc aacgcattca gctatatccc gccgatgaaa
     6121 ggtatattga acgccgattt ccagtacgct ccttccgact cggccttcat ggtcgtggcg
     6181 gatatgaaca ttgatgatct gtattatgag aacgagcggg tcggcgaact catgttcaac
     6241 gcagtctatc tacctttaga gcaggggaac catcaagtgg atatgcacct tttccgggac
     6301 cggaaagagg tgagtgccat taccgcctta taccagatgg gcgagaccga ccatatcagc
     6361 ggtactgtcg agttcatgca cttccccttg gatatcgcca acccgttcat tccggatgat
     6421 atggcgaaaa tgggcggaga cctcgatggt acgctcgcta tcagcggaca aagcgataaa
     6481 cccatggccg agggatatct gattctcgat accgcctccg tttatgtagg cgccgcaggt
     6541 tctaccttcc gtttcgacga taaaaagata gaaataaaga acaaccggat cttgttcaac
     6601 caatatggta tttacgcata caacaagaat ccgtttatca tcaacggaga agtggatttc
     6661 aacaatttat cccgcatgac cgccaatctt aaactaacgg cgaataactt gcaactgctg
     6721 aacgttaaga aaaacgaaga aagccttgtc tacggaaagc tgttcgtcaa cctgaattct
     6781 accgtacgcg ggccgttgga tgccttgacc atgcgaggcg acttgcaatt attgggcggg
     6841 acgaatatca cctacgtgct gaaagactcc ccgctgaccg tgcaagaccg tatgtcggac
     6901 atggtaacct tcacctcttt cacggatacc ttacgccggc gcatgcctcg taaacccccg
     6961 ttgccgatgg gaggcatgga catgctgatg acgatccaca tcgatcccgc cgtacaagcg
     7021 aacgtggatt taagtcccga ccagtccaac catatcaatc tggagggtgg cggcgatctt
     7081 tccttccagt ataccccgca aggcgatatg ttcttgaacg gacgctacac gctatccggg
     7141 ggaaccatca agtactccat cccggtgatc ccattgaagg agttcaacgt acaagagggt
     7201 agctacgtgc aatggacggg caaccccatg gacccgacct tgaaccttac ggctaccgag
     7261 cgagtccgta cgtccgtcac cctaaccggg caatcatcgc cccgcttggt gaatttcgac
     7321 gtaggcatcg aactgaccca acaactggag aacctagggt tgcaatttac cctcaccgcc
     7381 ccggaagaca tggcgatgca ggaggaactg acctcgaaag gcccggagga acgggcgaag
     7441 ctggctgtca gcatgctcgt gaccggtatg tacctcggcg gaggcggtgg tggcggcaag
     7501 gtgaacgtaa atatgggaga cgccttgacc agcttcttgc aaagcgagat caacaacatc
     7561 gccggaagtg ccttgaaatc cgtggatatc agcttcggca tggagacgta cgacgataat
     7621 ggcgacgccg gaggtggtac ccgtaccgac tactccttcc gcttcgccaa gcgattctat
     7681 aatgaccgta tccgtgtggt tctaggcggc cgtatctcta ccggcgagaa cattaacaat
     7741 ggacaggcgc agccgttcat cgataacgta tccgtagaat atcggttaga cagcagtggc
     7801 tcccgttacg tcaaactttt ccacgacaag aactacgaga gcctgctgga aggcgagatc
     7861 acggagaccg gagccggtat cgtgctccgc aagaaaatga tgcatctcag ggagctattc
     7921 aacttcaaga aaacgaaagt gaaaccagtg aaagaggaaa cagaaaagga atgaatatga
     7981 aaaatgtttt aatatatttt aggaaggatg ccctcctaga gcagggaaac atgccttccc
     8041 agagcaggga aacatgcctt cccaaagcag ggaaggatac ttccccaggg cgaggggggg
     8101 tgtctaccca aagagcgatc ctatcgtcgc tggcgctact cgggctgctg gccttcttac
     8161 tcacctcttg ctccaccacg aagaaccttc ccgagggagc ggtcctatat accggtatca
     8221 agaaaataga ggtgaagaac gaggataaga ccaaacccgg cgaagccgcc ttggaagagg
     8281 tcgaggccgc cctagcctat ccccccaaca acgccttgct gggaagctcc tcgatccggg
     8341 tgcccttccc cttcggcctg tgggtctaca acgctttcgt gaacaagaaa gggaaggtcg
     8401 gcaagtggat cttcaacaag ctggcgtcga aaccggtgct gatcaccacc gtgaacccgg
     8461 aagtccgtgt caaggtagcc cggaacctat tgaacgaata cggttatttc aatggagaga
     8521 cctctttcga ggtcgtaccc gatcccaaga atccccggaa ggcgaagctg gaatatagcg
     8581 tcaccatgaa cgatccgtat acgctagaca gcatccaata cgtccatatc cgtcaccgtg
     8641 ccgactcatt gatcgatgcc acgatcggcg atcgtatcct ccacaaagga gagaatttca
     8701 atgtcgtcca gttgcaagcc gagcgggaac gcatctcgtc cttgctccgt aacaacggct
     8761 attactattt ccgtcccgat ttcatcacct atcaagcgga taccttgttg aaccccggga
     8821 aagtggcctt acgggtggcc ccgaaggaaa gcctgccccc ctcggccctc cgcccttgga
     8881 agctcgggga tatatccgtc tggctaaacg gttaccagaa tgagactccc acggactcga
     8941 tccgctataa ggaccttacg atccattatg agggcaagct aagggttcgc ccctcggtca
     9001 tttacaaccg tttatatttc aagccggggg aactttacaa ccagcgggcg caggaacgga
     9061 cgcaaaccgc cctgtcccgc ttgggtatct tccgttatgc cgagttgcaa tattcccccc
     9121 gtgataccat gcgccgtcaa gatacgctgg atctgcggat caatacggtc tacgatcttc
     9181 cattggacgg cgagctcgag ttgaacgtta ccgccaagag caacgaccaa gtgggtccgg
     9241 gcgccatttt cagcgtgacc aaacggaatg tcttcggagg gggcgagacc ttcggcgtga
     9301 aactccgcgg ctcttacgaa tggcagaccg gcaacaagct ggatggtagc aactccaaga
     9361 tcaacagtta tgagttaggc ttgactacca cgctgacttt cccacgggta ttgttcccta
     9421 cattcagcaa acgggacatg aatttcccgg ccagcaccac cttccgcctc tatgcggacc
     9481 agatgaaccg ggcccgtttc ttcaagttgc tggcattcgg tggtgacgcc tcgtatgagt
     9541 tccagcctac tgccacgtct catcattcca tcaccccttt caagctgacg ttcaacttgc
     9601 tccagcatac cacgcacgag ttcgacagca ttaccaacgt gaataaggct ctaaaaaaga
     9661 gtttgcaaaa tcaattcatc ccggccatga actataccta tacctatgat gattccccga
     9721 ttaccagtcg ccggaaccat ctttggtggc aggcatccgt tacccaagcg ggccttgtct
     9781 tggatgggat ttatgcgtta gccgggaaga aattcaataa agaggataag gaattactcg
     9841 gcaacccctt cgcccaattc atcaagggaa ccgccgagat acgttataat tacgccctcg
     9901 ggcataagca atatctcgta ggccgattaa tggccggcgc tatttatagc tacggcaacg
     9961 cccgtacctc cccttataac gagcaattct acatcggcgg agcgaatagc atccgtgctt
    10021 ttacgatccg cagcatcggt cccggacgct actatcaaaa cagcgataac aataaatacg
    10081 cttacatcga ccgtacgggt gatcttaaat tcgaggccaa cctcgaatac cgcttcccga
    10141 tccttggcga cctgcatggg gccactttcc tcgacagcgg taacatctgg ctgatccgga
    10201 acgatccgga tcgtcccggc ggacaactga aatggggtag cttcctcaag gatctagcct
    10261 tgggaaccgg cttcggcctg cgttacgacc tcacctttat cgtcatccgt ttcgacgtgg
    10321 gtatcggtct gcatctccct tacgataccg gaaagaaagg ctattacaat atcccgaaat
    10381 tcaaggacgg catgggttac cacttcgcta tcggataccc cttctagctg ttccattcct
    10441 aggattctgt ggtcttatcc aaggtatttc attttcaata ggtcaaccct aattggaaat
    10501 gagatacttt tgcgctctca ttttaataac aaacagatta attaacgaac agaatcatga
    10561 agaagatttt ttacttaatg ttggtagccc ttactgtggg tatgttcacc gcttgcgacg
    10621 acgatgatga gaatacccct caaatcaaca acccggaacc caaggaacaa tggggcaaga
    10681 cgcttcgagg cgacaatcaa accctactgg cctttcctga tatctatgcc gattattggg
    10741 aatacaccta ttcttacaaa gataatccaa acatcggcct tcgtttgact ggaaagttcc
    10801 cgaagtcacg cttcttcaac ttcacggttt ataacgacga gacccaaata gacgtatcca
    10861 gcattgaaga cgtaaatatc caacccgacg acagctccat caacccttat gtaaaggaaa
    10921 cagatgacta cggagcaaat ggctatacga tttacatcat tcccgctaac acccccgcca
    10981 gcgcacgtgc ctcgatgaag aacgtatgtg agttcccgga ggatgtcaat atggtctcca
    11041 ttttcatgcg tctttacttg gcgaaacaat atagcggcga tgagtatggc ggcgtggaca
    11101 tgcctgctat ccaagctttc aacgtgacta caggtgagga agtagatttc ccgaagcgtg
    11161 aggtctgcaa catccacgaa tcgttgaact tgccgccgat ggatttctcc gccgacctgc
    11221 cgcaactccc gttcatgcgt gccccgctga gcctaatgta cccgaacagc ccggcagaat
    11281 acctattcgc ccgcatcaaa ctgaacgaag gggaggtagc aactttccgt ttcatccctc
    11341 ctacggctcc taaaagcgta agcgaatacg ccaccgccga tgtacgatac tggtccatat
    11401 gcctcgggtc agccgagacc tactcgtatg cctctattta cgacaaagaa atgcctaaag
    11461 tggacaagga aggtttcgta acctttatca tagcggacgc caactccgcc aaactgcccg
    11521 atctccaagc gaaggcggaa gccaacgacg gtacatatat actgacttgg aaccgtaagg
    11581 agcaaggaga tggaatcctt gccttatacc gcaacatggt gatcaacgag aattatccac
    11641 attccatgcg caagctgatg gagtccgttc ctctagcggc cgccggcggc gatatgagcg
    11701 gtttcaaccc gatgaagatg atcgccatgc tcgctatggg caactgggga ccgcaaggct
    11761 ataaattcag cgaggacgat ttcttgagcg atagcttcaa ttacgccaat atccgaagaa
    11821 tgaaataaac caatagacat atcgtatttt caagtcccct cgtatccggt cttaaccgga
    11881 acaaggggac ttccttttca cactcttatc ataaaccatg gaatttagat tccttataga
    11941 cgggcggtaa tataatcgat gatctgcaga caaaggtttg tggtctgctc gttcacgtcc
    12001 agctccggat tcagctctac caaatccatc gacttaacca gattcgtaga caacatatga
    12061 tccacgaagt tattaaactc atccggcatc agtccctcac acacacgggt tcccgtgccc
    12121 ggagcgaaac gggggtctat gctatccacg tctatgctga aatgcacgtt gcggatcttc
    12181 cgttccttca atttccgctt gatatcctca gctacgaagc cgatgccttt cagatggatc
    12241 gtctccatcg tatagacact cagcttctcc cgctcgatca aatcccactc gccctcatcc
    12301 agactgcggg tcccgaccaa gaatacgttc tgcggattca ccttattccc gggagcgtag
    12361 atattcacca gctcctcgct tcccatcccc atcaacgcgc taagaggcat cccgtggata
    12421 ttaccactgg gagaagtctc gctggtattg atatccccat gagcgtccag ccagataatg
    12481 ccgaaatcat cataacattt acccacgccc gaggcactac ctaaacccag cgaatgatcc
    12541 ccgccaatca ccaaggggaa cgctcctcca cgcaatgtat cataaaccaa ctccgccaga
    12601 ttcgtattca cctccacgat cgcatccaga tatttcatgc tgttaccccg tacgaactta
    12661 tccgcctcgc tgacaggggg tacatacaaa ttacccaaat caaaggcttt atgcccgttc
    12721 ttccggatca cccccatcaa tccccgttcc cgaaggtggt tcggggcacg ctctacgcct
    12781 gcccggtcac atcccaagtt caagggaacg cctattacat ttattttcat accctagaat
    12841 ttagcgaacg tatctcgtat aatgccaatc gcttccatca tttgctcctc cgtaatcacc
    12901 aaaggaggcg tgaagcggat gatatgatcg tgggtaggct tggctatcaa gccgttttcc
    12961 ttcaacgcca aacagatgtc ccatgccgtc ttcccatctt taggttccgt cacgacagcg
    13021 ttcaacaagc ccttaccccg tactttcttt atcataggat tattaatccg ctccatctca
    13081 ccacggaaca gctcacccat cttaaacgca ttctccgaca aatgctcgtc acgtaccacc
    13141 tccaaggcgg cgatagctac ctttgccgcc aacggatttc caccatacgt agaaccgtgc
    13201 tctcccggag cgatcgtaag catgatctca tcgtccgcca ataccgccga gaccggactg
    13261 accccaccgg acaacgcctt tcccaagatc aagatgtccg gacgaatccc ctcgtaatcg
    13321 caagccaata gcttaccggt acgaccgata cctgtctgta tctcatccgc gataaacaac
    13381 acattatgct gatggcaaag atcatagcaa gcccgcagat aaccatcgtc gggcaccacg
    13441 accccggcct caccttggat cggttccacc aagaagccta ctacatcggg atctttcaag
    13501 gcctcggcca acgcatccac attattatag ggtatcttta taaacccggg tgtataaggg
    13561 ccgaaatcgg cgtatgagct agggtccgta ctcatggaaa taatcgtaat cgtacgtcca
    13621 tggaaattct cgctacaaac cacgatcttc gcacgttccg gggcaacccc tttccgacga
    13681 tatccccacc gacggcaaag cttcaaggcc gtctctaccg cctcggctcc cgtattcatc
    13741 ggcagaagtt tgtcatagcc gaagaatttg caagtaaatt ccatgtattc accaagtata
    13801 tcagcatgaa aggcacgaga cacgagcgta agcctctccg cttgctccat cagggccttt
    13861 acgatcttag gatggcaatg tccttggctt aacgccgaat atccggacaa gaaatcaaaa
    13921 taacgttttc cctccacatc ccatacgaaa acaccttcgc ctcttctcag aaccacaggc
    13981 aggggatgat aattgtgagc accatacttc tcctcacggg tgatgtaatc ttccggtttc
    14041 atactgctac tgatttaaat gattagcata ctgtaagcgt ttcttaccgt atatgccaaa
    14101 gatacgaaat aggggattac aatatgtcac cgaaagcata tgttaagaaa catacattca
    14161 tgcaggtatt tatgaacgta gatacgtcgg ttaaccaaaa aggtgttgta aaaggcttct
    14221 tccgctcttt tacaacacct ctctatcaaa atcaattgga acttataaag ttgtcaaata
    14281 gttcttcaac ggattggagt acatctccaa tagtttctta cgtaagaacg cctcatcctt
    14341 attcggaagg acgatcttgt ccaactgtcc ttgtatatac tcctcgaact gcttcttatc
    14401 cttcggtccg taatgctcgt ggaaacggcg agtaccgttc agccaatcat aagctacgta
    14461 attacaagaa tagaaacgat agttcttata gatctcccgg tcgataacgg acgcgatagc
    14521 gcttaccagc tcattcttct ccatatcctt gtccagttta gccaaggaat cattgatcgg
    14581 ggaagtaatc gtaaagtgga cacgaccctt attgttcaag atacccgttt ccatgctcaa
    14641 caaatcatcc cgctgacatt tcacgaaatc cggatcatcc cgcttcatct gaaattcttt
    14701 cgccttcaag aaatcgcaag gatcaaactc gtaggagata gcgaccggca cgatattcaa
    14761 atccatcaaa ttcaacaaca gattatcctt atcaccgccg atactcaaca tttttaatac
    14821 gctgccctgc gtacgatcgt ccgaatcctt agcacgtccc tcacgctggg cgatccatac
    14881 agactcgttc acattcttga tcacatgatg gatataggcg gaaagcgtct tgctgacctc
    14941 caacatctga cgaacagaaa cgccacgctt cacaataaaa ctattgttca agcgtaccaa
    15001 tgtctcgatc cacggacgga ttaaaagatt gtcgccgata gcgacctgcg tcataccata
    15061 ccccacatca tataacatga cattcaagaa ggaggcatcc aatacgatat ccctatggtt
    15121 cgagataaac gtacaggccg ccttatcttt cggcagacgg ctacgccctg agatagtaag
    15181 cgagaaagta gtatttttcg ccaccgtcat tacagcgtca taggccagag tagatttaaa
    15241 ctcctccttc gtcttgcaag cacgcatggc aactgagaat tcctcccaat tcaaattcgg
    15301 ctttatgtaa cgtaaagccc gctcgaaatc ctcattggcg accaattttt caatcgcgtc
    15361 cttcacctca ctgttgttca gcggacggat gtcgtcgaaa ttaggggaaa ctgtttctgt
    15421 atccatatct attcattttg tttttctgtt tttgagttcg tcttcaataa tgtctgtcat
    15481 gacatccttt atatccaatc ccgccgcacg tacttgctgt gggataaagc tggtagccgt
    15541 cattcccggt gtcgtgttta tttccagtaa gacaggctcc ccgtctgccg gaataatata
    15601 atccacacga atcagtcctt tggcgcccaa tatatcgtag atccttgatg tcttgcgctg
    15661 tatcaactcc gtcaactcgg cggagatacg ggccggagtg atctcgtcca cctgcccgtt
    15721 atactttgcg tcgaaatcga agaattcgtt atccgtaacc acctcggtca aaggaaagac
    15781 aacctcttta ccctccacct tatagcaacc gcatgtcact tccgttccat cgataaagct
    15841 ctcaagaatc acctcacgtc cttccccaaa cgccttagcg atagcgggct ggatagcgga
    15901 gagctctttc accttcgtca cgccgaaact actaccccca tcgtttggtt tcacgaaaat
    15961 aggcaaaccc aaacgagtca cgacttcttc gtccgtaata gtctctccct tgaataaatg
    16021 aatggatgcg gcaattttta caccaaagtc tttcaagtaa tgattacata cgtatttatt
    16081 gaatgtcaaa gcgctcacca gcatcccgca agacgagtaa ggcataccga tcatatcgaa
    16141 atatccttgc aaacgtccgt cctcgcccgg agtaccgtgt atcgttatat aagcgaagtc
    16201 aaaatgcctc gtcacgccat tctccttgaa gctaaaatca ttcttatcaa ttggtgtatg
    16261 ttccccgcta ggaagtataa ccgcccactc atccctctta acgatggcaa tatataaatt
    16321 atatttgtct ttatcaataa aagagtagat tccgtccgca ctttttaatg aaataacgat
    16381 ctcggaggaa tctccccctg ctacgatagc gatgttcttt ttcattttta tagttcttta
    16441 gtgttcgcgt atacacgcca tctgtcgatc agctgctgca tatcggaagg aatctcggaa
    16501 tcgaaaaaca tctcctctcc cgtagtagga tgaacgaacc ccaacgtctt agcatgcaag
    16561 gcctgacgtg gacaaatagc gaaacagttt tgcacgaact gtttatattt agtaaaagtt
    16621 gttcctttca agatatcatg tccgccatac cgctcatcgt tgaaaagcgt atgaccgata
    16681 tatttcatat gtacacggat ctggtgcgtg cgccccgtct ccagacggca ctccaccaaa
    16741 ctcacgtagc ccaagcgttc caatacggtg taatgggtga cggcagtctt gccttgatcg
    16801 ccttccggga agacggtcat ttgcatacgg tcacgagggt cacggccgat atttccctcg
    16861 atacgcccct catcctcttg aacgatgccc cataccaagg cacggtattt acgtttggtt
    16921 gtcttgttga agaactgcag gcttaggtta ctcttggcct ccgggcgttt agccaccacc
    16981 aataagcccg acgtatcctt atcgatacgg tgtaccaagc ctaaacgagg atcggaagga
    17041 tcataatagg gatcatcctt caaataataa gccaaggcat tcaccaacgt accggtataa
    17101 ttaccgtgac cgggatgtac gaccaagcct gccggcttat tcaccaccag caaatcatcg
    17161 tcctcatata ctatattcaa agggatatct tcggggataa tctccagttc ccggcgtggg
    17221 cgatccatca cgacagaaac cacatccaaa ggtttcaccc ggtaattact tttcaccggc
    17281 ttatcgttca ccaagataca acccgcctca gccgccaatt ggatgcggtt acgggtagcg
    17341 cccatcatac ggtctaccaa gaacttatcc acccggagca gggattgccc cttgtccgct
    17401 acgaaacgga aatgctcata catctggctc gacgatgttt cgtcttcttc cggcatcaac
    17461 aggtcgtcta cctgttcatc atccatatcg tccaaaaact cgtccattcc cttaaaacca
    17521 gttttctata tcactatcca atggttctac cggaatacta tccaaagcca atgagtcggg
    17581 aagcatattc ggatcgccac tgcttacttt caataccaga tgagcggtca acggtacatg
    17641 ttcccctttg agcaaggtac gcccgtttaa ctccaccccc atcgccaaat ctttataatc
    17701 gcccggcaca tactctatct cgaccgacga gaagccacgg gcccgcagca aggcatacgc
    17761 ctgacggaaa gataagtctt ccacctccgg tatcacggcc atctgggagg tcaacgcgtt
    17821 aatcgtaaca aagacgatcc gcccctcttt caccttcgat ccgacaccgg gaaccaactc
    17881 cacgatggag cccggagcca catctttcga gaatacggaa tcgatcacgt tatagcgtag
    17941 cttattattc ccgaaaaact cggcggcgtc ctctagcttc attcctttca cgtccggaac
    18001 gaccaccgct tgattatggc gggtataaga atccagccac gccagcacgc cataaacaac
    18061 gccgcacgac acgactatca ccaacaagag attgatgaca aacggattct ttatcagttt
    18121 tacaaaaaag ttactcattt cacgtatgta tttgtaggcg gttcaaaagt agaaaaaaaa
    18181 cggcatatag accaatatcc accagagcaa tactacaaaa acaaagaaag taaaggcttt
    18241 ttaggaaaaa acctctactt tctttataaa tctttagaac gtgactaatt atccgttgta
    18301 ttcgtcagat accgttaatt tagctctgcc tttagcacga cgagaagcta atactctacg
    18361 gccattagcg gtagccattc ttgaacggaa gccatgcttg ttctttcttt ttctgttgga
    18421 aggttggaat gttcttttca tctttctata ttatttatta ttattcgcat acttattcgg
    18481 gctgcaaaga tagagccttt tttttaataa acaaagggtt gcgcaatttt ttacgcaaga
    18541 acctttgat
//
LOCUS       DBMDTB010000082        17646 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_1036_length_17646_cov_11.168880, whole genome shotgun
            sequence.
ACCESSION   DBMDTB010000082 DBMDTB010000000
VERSION     DBMDTB010000082.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 17646)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 17646)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17646
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1036_length_17646_cov_11.168880"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..246
                     /locus_tag="ACZPB4_12505"
     CDS             <1..246
                     /locus_tag="ACZPB4_12505"
                     /EC_number="3.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconolactonase"
                     /protein_id="HIR1099068.1"
                     /translation="MELLSDSRNYAVSQQPSTGQYRITMTGPLILNGAPLLVPILGTN
                     KEPVIQRLSKGYSPSNDTPAAYILSHAVQATIYGLNP"
     gene            607..1131
                     /locus_tag="ACZPB4_12510"
     CDS             607..1131
                     /locus_tag="ACZPB4_12510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside 2-deoxyribosyltransferase
                     domain-containing protein"
                     /protein_id="HIR1099069.1"
                     /translation="MNMRNIVLCILYLFLVPMGGFAQSEVIVLYPDTENKDFDEAVYQ
                     KIFLAGTIDMGKSVDWQKATCDWFRALPEGRYLLFNPRRDKGLSGEMSDFEHQVNWEL
                     EHLEKADLIIMNILASSKSPITLLEMGLFMRSGKLRVICEPGFYRYDNVRLTCARYGV
                     PLYQNMDDFLKTMR"
     gene            1220..2095
                     /gene="rfbA"
                     /locus_tag="ACZPB4_12515"
     CDS             1220..2095
                     /gene="rfbA"
                     /locus_tag="ACZPB4_12515"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HIR1099070.1"
                     /translation="MKGIVLAGGSGTRLYPITKGVSKQLLPIYDKPMIFYPVSVLMLA
                     GIREILIISTPQDLPGFRRLLGDGSDYGVRFEYAEQPSPDGLAQAFIIGERFIGDDSV
                     CLVLGDNIFYGQSFTRMLKEAVDKAENEQKATVFGYYVNDPERYGVAEFDADGNVLSI
                     EEKPKEPKSNYAVVGLYFYPNKVVGVAKNIKPSARGELEITTVNQWFLKDGELKVQLL
                     GRGFAWLDTGTHDSLSEASTFVEVIEKRQGLKVACLEEIAFKQGWIDEKRLEQVALPM
                     IKNQYGQYLMRLINK"
     gene            2121..3197
                     /locus_tag="ACZPB4_12520"
     CDS             2121..3197
                     /locus_tag="ACZPB4_12520"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-L-fucose synthase family protein"
                     /protein_id="HIR1099071.1"
                     /translation="MEKDSKIFVAGHRGLVGSAILNNLRSKGYTNFLLRTHAELDLTD
                     QAAVNEFFAAERPDYVFLSAAHVGGIMANSLYRADFIYNNLMIQNNVIHASWKNNVKK
                     LLFLGSTCIYPREAPQPMPEDCLLTSPLEYSNEPYAIAKIAGIKMCESYNLQYGTNYI
                     AVMPTNLYGPNDNFNLETSHVLPAMIRKIHLAKCLHTGDWEALRKDMDIRPVEGVSGK
                     ASEPEILSVLDKQGIRPGEVELWGTGKPLREFLWSEEMADASVYIMEHVDFEDVRQKE
                     GEVRNTHINIGTGIELSIREVAELIRREIGFEGELRFNSSKPDGTLRKLTDVSKLHAL
                     GWRHTIEIEEGVKRLYEWYLGIEK"
     gene            3223..4374
                     /gene="gmd"
                     /locus_tag="ACZPB4_12525"
     CDS             3223..4374
                     /gene="gmd"
                     /locus_tag="ACZPB4_12525"
                     /EC_number="4.2.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005635384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008446 - GDP-mannose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0019673 - GDP-mannose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
                     /protein_id="HIR1099072.1"
                     /translation="MGKVALITGITGQDGAYLTEFLIKKGYTVHGIKRRSSMFNTDRI
                     DHLYQDPHVENRNLILHYGDLTDSLNLTRIIGEVQPDEIYNLAAMSHVKVSFDTPEYT
                     ANADGLGVLRILEAVRLLNLIPKTRIYQASTSELYGLVQEVPQRETTPFYPRSPYAVA
                     KLYGYWITVNYREAYHMHASNGILFNHESPLRGETFVTRKVTRAVSRIVLGMQKKVYM
                     GNLSSKRDWGHAKDYVRAMYAILQQDEPSDYVIATGITTTIRDFIRMAFEEIGVGIRF
                     KGEGIDEVAIIESIDEGLFVKKVGDAYLENFKKRVGEEVVGVDPQYFRPTEVELLIGD
                     ATKARTRLGWEPEYSLAALIEDMMKNDIKLMKKESYLKEGGYKILNYFE"
     gene            4482..5627
                     /locus_tag="ACZPB4_12530"
     CDS             4482..5627
                     /locus_tag="ACZPB4_12530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015288 - porin activity [Evidence IEA];
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HIR1099073.1"
                     /translation="MKTKVLLLALLSGFVFSVAAQEYQPQVGFSNEAGYKTNFKKNKA
                     RDNWFISIAGGASVLLGDQNGEADFKNRLNFAPQVSFGKWFNPYLGFRTQLNGGIIHG
                     FEGDGAQFMQHNKYVAAHVDLLWDVTNFWAPYRESKVFRLIPWVGFGYAQRFKTTESY
                     DRPRTESPTLNAGILTAFRLSKRVDLNVEIQGSLLNEQFNRVEMNHLTDGIVQLSAGL
                     TFKLGKTDFEVLEPMDYALLNDLNGQINSLRAANDELSKRPVSCPECQETVTEVVNNY
                     VDNVVYFRINSAKIDKNQQINIYNTAEFMKNNNAPIKVVGYADKKTGTSDYNMGLSEK
                     RARAVAKELIDKYGISSSQITIEWRGSDEQPYGENSWNRVVIMSANN"
     gene            5724..7121
                     /locus_tag="ACZPB4_12535"
     CDS             5724..7121
                     /locus_tag="ACZPB4_12535"
                     /EC_number="2.7.8.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-phosphate glucose
                     phosphotransferase"
                     /protein_id="HIR1099074.1"
                     /translation="MILNKKHGYLIQWLIGVGDLIVLNLLFMAVFHLLGPKYTEAISY
                     NLREVILLLNFCYFFSLYFIPIQLHQAVVFIDKIVQRAFGLVTVLIFLFATCLIFLNV
                     GDILATFLLVYYGVSIILFSLWRVFVRLSLKFYRRKGYNFKKVVIVGAGKNGMELYQV
                     MKDDLSYGFSVKGFFDDNDSLKDVLPNYLGKTSEVEAYVLEHDIDEIYCTLPGTNNGK
                     IVRLLNFAEKKMVRFYIVPEFYRDVKKSMVMEVMESIPLLTVRREPLQSAYNRFLKRT
                     FDIFFSLVILLTIYPILYIVVGIMIKLSSPGPILFKQKRTGLYGHDFECFKFRTMKVN
                     AQADTLQAVKDDPRKTRIGDFLRRTNLDEFPQFVNVLLGDMSVVGPRPHMLKHTEQYS
                     ALIDKYMVRHLVKPGVTGWAQVTGYRGETKTLEQMEGRVKRDVWYIENWTFFLDLKII
                     VVTVLNMFKGEKNAY"
     gene            7191..7613
                     /gene="ruvX"
                     /locus_tag="ACZPB4_12540"
     CDS             7191..7613
                     /gene="ruvX"
                     /locus_tag="ACZPB4_12540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HIR1099075.1"
                     /translation="MGRIIAIDYGRKRTGIAATDILQMIANGVATVPSGEVVKYLSDY
                     ISREPVDLFVVGLPKQMNNEPSENMKYVEAFVTHLKRTIPSIPVTYYDERFTSVLAHK
                     AMLEGGLKKKKRQDKGLVDEISAVIILQAYLESKKYQL"
     gene            7617..8174
                     /gene="def"
                     /locus_tag="ACZPB4_12545"
     CDS             7617..8174
                     /gene="def"
                     /locus_tag="ACZPB4_12545"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HIR1099076.1"
                     /translation="MILPVFLYGQPVLRKEAEDVPKDYPDLKQLVANMFETMYNADGV
                     GLAAPQVGLSIRLVVIDGDVMGDDFPECKGFKRALINPEFLERSEEEIAMEEGCLSLP
                     GIHEKVSRSKTVRVRYWDENWEEHEEVVEGFAARIVQHECEHLTGHVFIDNVSAIRRQ
                     LNKGKLNSIIKGTVRCSYRAKAVGK"
     gene            8195..9742
                     /locus_tag="ACZPB4_12550"
     CDS             8195..9742
                     /locus_tag="ACZPB4_12550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008147311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA carboxylase subunit beta"
                     /protein_id="HIR1099077.1"
                     /translation="MTDLSKNIEALREKKAVIEMGGGEAAIEKQVAMGKLTARERILA
                     LLDKNSFHEYDMFVKHDGRDFGMEKKVLPGDGVVTGTGTIFGAPVCIYAQDFTVAGGS
                     LGLQHARKITKIMDHALKMKCPIIGINDSGGARIQEGVGALAGYGEIFYRNTIASGVI
                     PQISLILGPCAGGAVYSPALTDFVFVVENISKMFITGPNVIKTVLGEDISMEDLGGAR
                     VHAETTGNAHFYALSEQECFDQVKRLVSFIPWNNQERAKVVEPKEPSAMLNIEQVVPA
                     DPKQPYDVRDVIRCIVDDSDFLEIQELWAANIVIGFGRMAGETVGFVANQPMVLAGVL
                     DCDSADKAARFIRFCDSFNIPIITLEDMPGYLPGVDQEHAGVIRHGAKVLYAYSEATV
                     PKITVILRKAYGGGYIAMNSRHLGADFMFAWPSAEIAVMGPEGAANIIFRKEIMEAED
                     QNAMRQEKVKEYIEKFANPYVAASKGFIDSVIEPKETRSLLLHALKLSILKEEYRPAK
                     KHGLPPF"
     gene            9755..10087
                     /locus_tag="ACZPB4_12555"
     CDS             9755..10087
                     /locus_tag="ACZPB4_12555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016421 - CoA carboxylase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA carboxylase biotin carboxyl carrier
                     protein subunit"
                     /protein_id="HIR1099078.1"
                     /translation="MEKKHQQEEYVDFVVTARKYKTLLTAKYKSRPMWHKPSAGDVVS
                     HLPGTIIKIMVEEGQAVEAGQLLLIHEAMKMQNRVVAPISGVVVELNVKEGDKITKNH
                     LMVKIESK"
     gene            10129..12252
                     /locus_tag="ACZPB4_12560"
     CDS             10129..12252
                     /locus_tag="ACZPB4_12560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HIR1099079.1"
                     /translation="MKKATLFLILQIFTISLFAQINTDRVLAIGRNALYFEDYVLSIQ
                     YFNQVIKSKPWLAEPYFYRAVAKINLDDFKGAEEDCTLCLQRNPFLTQAYYARGIARQ
                     SQEKYDEAIDDYQKGLEFKPEDRQMLVNMAVAFIQKKDYNGAEKTFDDLMTAHPKYSM
                     NYMTRGAMYLEKGDTLKALADYNKAIEMDPYYAPAYGNRAILHYQMDDYKDALADLNE
                     ALRLDTRESGYYINRGLVRYQMNDLRGAMADYDQVISMDSRNLIARFNRGLLRFQVGD
                     NNRAIEDFDVVIQQEPDNYMAYYNRALLRFETGDYRGAVQDYDVVLKQYPTFLPGFVS
                     RSEAKRKLGDNVGADRDYWAAIKMEEQAKNGQLPKTSSSSSNTAVNGDAKTDDSEENT
                     REQSDKNINKFNRLVVYDKEQERKSKYQSEVRGRVQDRNVHVDLEPQFVLTYYEKADP
                     VKKLVYYDKMVEDYNGQMVLKRKLRITNEEAALTEDQIAVHFASIDEYSAEIERDPNN
                     ANAYFGRAMDFMLVQDFSEAIKNFSEAIERDPSFTMAYFNRAVERYKQLMYTQSQQAS
                     KDTYDLSGSGMNLNIGKSAQSQVNANTSVDLRSAMLKDNKRAYEHEQIMRDYDMVIKL
                     NPGFVYAYFNRANLRCAQRDFRAAIVDYNEAIERDPEFAEAYYNRGLARLSQGDVNRG
                     IADLSKAGELGIYNAYSIIKRMTSR"
     gene            12343..14298
                     /gene="thrS"
                     /locus_tag="ACZPB4_12565"
     CDS             12343..14298
                     /gene="thrS"
                     /locus_tag="ACZPB4_12565"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HIR1099080.1"
                     /translation="MIKITFPDNSVREYAKGTTAMQIAESISSRLAQEVLAASVNGEV
                     WDLSRPINDDATVKLLKWEDEEGKHAFWHSSAHLMAEALQELYPGIKFGIGPAIENGF
                     YYDVDPGEAVIKEGDFAAIEAKMLELVAKKEEIKRQDITKADAMKMFGDRGEEYKTEL
                     ISELEDGTITTYTQGSFTDLCRGPHLPNTSYLKVVKILSVAGAYWRGDEKRKQLVRLY
                     GITFPKKKMLDEYLTLLEEAKKRDHRKIGKEMDLFMFSDTVGKGLPMWLPKGTALRLR
                     LQEFLRRIQARYNYQEVMCPPIGNKLLYITSGHYAKYGKDSFQPIHTPEEGEEYFLKP
                     MNCPHHCMIYKNSPRSYKDLPLRLAEFGTVCRYEQSGELHGLTRVRSFTQDDAHIFCR
                     PDQVKQEFLNVMDIISIVFKTMNFENFEAQISLRDKVNREKYIGSDENWEKAEQAIVE
                     ACEEKGLKAKIEYGEAAFYGPKLDFMVKDAIGRRWQLGTIQVDYNLPERFQLEYTGAD
                     NQKHRPVMIHRAPFGSMERFVAVLIEHTAGKFPLWLTPEQVCIMPISEKFNDYAWQIA
                     RELGNQEIRAIVDDRNEKIGRKIRDNELKRIPYMLIVGEKEAENGEVSVRKQGEGDKG
                     SMKIATFAALLNGEVEEMMNRWQKSND"
     gene            14332..14958
                     /gene="infC"
                     /locus_tag="ACZPB4_12570"
     CDS             14332..14958
                     /gene="infC"
                     /locus_tag="ACZPB4_12570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HIR1099081.1"
                     /translation="MKNDNLKEQYRINERIRVREVRLVGDNIETGVYPIAQALKIAEE
                     QGMDLVEISPNAAPPVCRVIDYQKFLYQQKKRQKEQKAKSVKVVVKEIRFGPQTDDHD
                     YNFKLKHAKGFLEEGSKVKAYVFFKGRSILFKEQGEVLLLRFANDLEDYGKVEQLPVL
                     EGKRMIIMLTPKKAGTGSAPAAAAAPKVVKKVITTPKPKSEGDKKTEE"
     gene            15014..15211
                     /gene="rpmI"
                     /locus_tag="ACZPB4_12575"
     CDS             15014..15211
                     /gene="rpmI"
                     /locus_tag="ACZPB4_12575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016273436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HIR1099082.1"
                     /translation="MPKMKTNSGAKKRFALTGSGKIKRKHAFKSHILTKKTKKQKRNL
                     THTGLVASVDVSNVKQMLCMK"
     gene            15317..15661
                     /gene="rplT"
                     /locus_tag="ACZPB4_12580"
     CDS             15317..15661
                     /gene="rplT"
                     /locus_tag="ACZPB4_12580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005469617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HIR1099083.1"
                     /translation="MPRSVNHVASRAKRKRILKLTRGYYGARKNVWTVAKNTWEKGLT
                     YAFRDRRNKKRNFRALWIQRINAAARMEGLSYSRLMGALHAAGIEINRKVLADLAVNH
                     PEAFKAIVAKVK"
     gene            16188..16493
                     /locus_tag="ACZPB4_12585"
     CDS             16188..16493
                     /locus_tag="ACZPB4_12585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008997339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISAon1 family transposase N-terminal region
                     protein"
                     /protein_id="HIR1099084.1"
                     /translation="MEYFEISGWHDDSVKIEVWLDEKNYMERSDYKSGTVISHGFTDE
                     KVIQDFPLRGKPVYLHVRRRRWYDKATGETFSYTYDDLTAEGTKLTPEFVAFLKEED"
     gene            16501..17472
                     /locus_tag="ACZPB4_12590"
     CDS             16501..17472
                     /locus_tag="ACZPB4_12590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011964719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISAon1 family transposase"
                     /protein_id="HIR1099085.1"
                     /translation="MASISSIADAYGVKGKQLTSQYKGFISAYRQWDQLDHASEYVLF
                     KQNIGPSLCIDETSLSCGELYTVVTNRAGRGGKGTLVAMIRGTKSEDVIKVLEMIHVS
                     KRKTVKEVTLDLSPTMMRIVRTAFPNATMTNDRFHVQKLFYEAIDELRITYRWMARDL
                     ENDEIQRCREQDIEYVPFRYTNGDTRKQLLARAKHVLVKHFSKWTESQRIRAEIIFEH
                     YPELKSVYDLAIELTNVYNKHYNKDVARGKLALWYNKIEKLGYGCFRTVTNTMQNYYE
                     TILNYFVNRETNAFAESFNAKIKAFRAQFRGVGDIPFFIFRLCKLTG"
     gene            complement(17461..>17646)
                     /locus_tag="ACZPB4_12595"
     CDS             complement(17461..>17646)
                     /locus_tag="ACZPB4_12595"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099086.1"
                     /translation="CKTMYGGSNPPGTSEESLEVVCNERFEAFFVLSVRNSRRVVGRF
                     AVLGQSENPVGMLNLPC"
BASE COUNT         4832 a         3393 c         4662 g         4759 t
ORIGIN      
        1 atggagctat tgtcggatag ccgtaactat gcggtatccc agcaaccttc taccggccaa
       61 taccggatca ccatgacggg accgcttatc ttgaacggcg ctcccttatt ggtcccgata
      121 ctgggcacga acaaggaacc cgtaatccag aggctctcca aaggctattc cccctcaaac
      181 gatacgcctg cggcctatat cttatcgcat gccgtacagg ctacgattta tgggctgaac
      241 ccatgatttt gctacatgcc gagtccttcc aaaaaacatg tacgtgtttt cgaaaaaaca
      301 cgtacgactt tttggaaaaa cacgtacatg ttttcggaat cttgtgatca tgttcctatg
      361 acttgatttg tagtgagata agatactata cgttttgcct tgaatcgagt gtttacatat
      421 actcctctcc ttggagaaga tatactgcaa gtaccctagg agatatactt caccgtccaa
      481 gtaagtacta cttctcgtga tatcctatta gtatatacaa gactgttgcc ttcatttaaa
      541 gtgaatgtat ttgttggatt catgtttttt tgcgaagttt gttgcttgaa aagtaagctt
      601 tgagacatga atatgagaaa tattgtactg tgtatattat atttgttttt ggtgccgatg
      661 ggagggtttg cccaatctga ggtcattgtc ttgtatcccg atactgaaaa taaggatttt
      721 gatgaagctg tataccaaaa aatctttttg gccggcacga ttgatatggg gaaaagcgtg
      781 gattggcaaa aggctacctg cgactggttc cgggcgcttc cggagggacg gtatctcttg
      841 ttcaatcctc gtagagataa agggttgagc ggggagatgt ccgattttga gcatcaagtg
      901 aattgggaac tggagcatct ggagaaagcc gatctgatta tcatgaacat tctggcgagc
      961 agcaaatccc cgataacttt attggagatg gggctgttta tgcgctccgg aaagttgcgg
     1021 gtgatttgcg agcccggctt ttaccgctat gataatgtgc gcttaacttg tgcgcgctat
     1081 ggcgtcccat tgtatcagaa tatggacgat tttttgaaaa ccatgcgcta atctattatt
     1141 atttgtttaa ctttgtatag ttttagggac ggtgtggaat cgatcctaag cgagtattgt
     1201 cgaacaaaat ggaaagaata tgaaaggtat agttttagcc ggtggatcgg gtacccgctt
     1261 gtatccgatc actaaaggag tttccaagca acttctacct atttatgata agccgatgat
     1321 tttttatccg gtatccgtgc tcatgctggc agggatacgg gagattctta ttatatcgac
     1381 ccctcaggat ttgccgggct ttcgtcgttt actgggcgat ggctccgatt atggcgttcg
     1441 ttttgaatat gccgagcagc cttcaccgga cggattggcg caagctttca tcattggaga
     1501 gcgttttatc ggcgatgact ccgtttgctt ggtacttggc gataatatct tttacggaca
     1561 gagctttacc cgtatgttaa aagaggccgt tgacaaggcg gagaacgaac aaaaagcgac
     1621 cgtgttcggt tactacgtaa acgatccgga acgctatggc gtggccgagt tcgatgcgga
     1681 tgggaacgtc ctcagtatcg aggagaaacc gaaggaaccg aagtcgaatt acgccgtggt
     1741 aggattgtat ttctatccga acaaggtggt gggcgtggcc aagaatatca agccatccgc
     1801 ccgtggagag ctggagatca ctaccgtgaa ccagtggttc ttgaaggatg gggagttgaa
     1861 agtgcagcta ttgggacgtg gattcgcttg gttggatacc gggactcacg actcgttgtc
     1921 tgaggcatct actttcgtgg aggtgatcga gaagagacag ggactgaagg tggcttgtct
     1981 ggaggagatc gctttcaagc aaggatggat tgatgagaag cgacttgagc aagtggcttt
     2041 gccgatgatt aagaatcagt acggccagta tttgatgagg ttgattaata agtagaagta
     2101 gttcagaata cgagatatcg atggaaaaag acagtaaaat atttgttgcc ggtcaccggg
     2161 gcttggtagg ctccgccatc ctgaataatt tgcgtagcaa agggtatacg aacttcctgc
     2221 ttcgtacgca tgcggaactg gatctgacgg atcaagccgc tgtgaacgag ttctttgcag
     2281 ccgaacggcc ggactatgtg ttcttgtcgg cggcgcacgt cggcggtatc atggcgaaca
     2341 gtctgtaccg tgccgatttt atctacaata atttgatgat ccagaataat gtcattcatg
     2401 cctcttggaa aaacaatgta aagaaattat tattcttggg aagcacctgc atctatcccc
     2461 gtgaggctcc gcagccgatg ccggaggatt gcttgctgac atctcccttg gaatattcca
     2521 acgagcctta cgcgatcgcc aagatagcgg gtatcaagat gtgcgagagt tacaacctgc
     2581 aatacggtac gaactatatc gccgtgatgc ctaccaacct ctacgggccg aatgataatt
     2641 tcaatctgga gacctcgcat gtgttgccag ccatgatccg taagatccat ctggcgaaat
     2701 gcctgcatac aggagattgg gaggccttgc gtaaggatat ggacattcgt ccggtagagg
     2761 gcgtgtctgg gaaggcctcc gagccggaga tactctccgt attggataaa cagggtatcc
     2821 gtccgggcga ggtggagctg tggggaaccg gcaagccgct tcgtgagttt ttatggagcg
     2881 aggagatggc cgacgcttct gtttatatca tggaacacgt ggatttcgag gatgtccgcc
     2941 agaaggaggg cgaggtccgg aatacacata ttaatatagg tacgggtatc gagctttcga
     3001 tccgtgaggt cgccgaactg atccggcgag agatcgggtt cgagggcgag ttgaggttta
     3061 actcgtccaa gccggacggt acgcttcgta agctgacgga tgtaagcaag ttgcatgcct
     3121 tgggttggcg ccatacgatc gagatcgagg agggcgtgaa gcgactctat gaatggtact
     3181 tgggaattga aaaatgagaa ttgaaaattg aaaattagag aaatgggcaa agtagcgtta
     3241 ataacgggta ttacgggaca ggatggggct tatcttactg agttcttgat caagaaagga
     3301 tatacggtac acggtatcaa gcgtcgttct tccatgttca atacggaccg tatcgatcat
     3361 ttgtatcaag atccgcatgt ggaaaaccgt aatttgattt tgcattatgg cgatttaacg
     3421 gatagtttga atcttacacg tatcattggc gaggttcaac cggacgagat ctataatctg
     3481 gccgccatga gccatgtaaa agtaagtttc gacactcccg aatatactgc gaatgcggat
     3541 ggtttgggcg tattgcgtat cctagaggcg gtccgtttgc tgaacttgat cccgaagacg
     3601 cgtatttacc aggcatctac atccgagttg tatggcttgg tgcaagaggt gccgcagagg
     3661 gagactactc ctttctatcc gagaagccct tatgcggtag cgaaactata cggttactgg
     3721 attacggtga attacaggga agcctatcat atgcacgctt ccaatggcat cttgtttaat
     3781 catgagtctc cattaagggg agagacattc gtgacccgta aggtaacccg ggcggtttca
     3841 cgtatcgttt tgggtatgca aaaaaaggtt tatatgggta atctttcctc caaacgggat
     3901 tggggacacg caaaagatta cgtgcgtgcc atgtacgcta ttttgcaaca agatgaaccc
     3961 tcggattatg tcatagctac cgggattact accacgattc gggactttat ccgtatggct
     4021 tttgaggaaa ttggcgtggg aatccgcttt aaaggagaag ggatagacga ggtcgctatc
     4081 atagagtcga tagacgaggg attgttcgtc aagaaggttg gtgatgccta tctggaaaac
     4141 tttaagaaac gtgtgggtga ggaagttgtg ggagtagatc cgcagtattt ccgccctacg
     4201 gaagtagagt tgctgatcgg tgacgctacg aaggcacgta ctcgtttagg gtgggaaccg
     4261 gagtattcat tagcggcttt aattgaggat atgatgaaga acgatataaa actaatgaag
     4321 aaggagtctt atctgaaaga ggggggctat aaaattttga actatttcga gtgagttcga
     4381 aacaatttga agattttatt tgttgtaatt acaaaaagag ttaaatttgt gccaatttta
     4441 agatattagg taattgattg tttaattaaa atgttgaaaa tatgaagact aaggttttac
     4501 ttttagcttt gttatcaggt tttgtattct ctgtggcagc acaggaatat caaccgcagg
     4561 tggggttcag caatgaggct ggttataaga ctaatttcaa gaagaataaa gctcgcgaca
     4621 attggtttat ttcaattgcg ggtggagcca gcgtattgtt aggagaccaa aatggagagg
     4681 ctgatttcaa gaatcgttta aacttcgctc cacaagtatc ttttggtaag tggtttaatc
     4741 cgtatttagg attccgtacc cagttaaatg gtggtattat ccacggtttt gaaggtgatg
     4801 gcgcacagtt tatgcaacat aataaatatg tagccgctca cgtagatttg ttgtgggatg
     4861 ttactaactt ctgggctcct tacagagaat ctaaagtgtt ccgcttgatt ccttgggtcg
     4921 gttttggtta tgcgcagcgt ttcaagacta cagagtctta tgatcgtcca agaacggagt
     4981 ctcctacgtt gaacgctggt atcttaaccg ctttccgttt gagcaaacgt gttgatttga
     5041 acgttgagat ccaaggttct ttgttgaacg agcagtttaa ccgtgtcgag atgaatcacc
     5101 tgacagatgg tatcgttcag ttgagcgctg gtttgacatt caaattgggt aagacagact
     5161 tcgaggtatt ggagccgatg gattacgctt tgttgaacga cttgaacggc cagatcaact
     5221 ctttgcgtgc tgctaacgat gagttgagca aacgtccggt ttcttgccct gagtgccaag
     5281 agacagttac tgaagttgta aataactacg ttgacaatgt ggtttacttt cgcatcaaca
     5341 gcgctaagat cgacaagaac cagcagatca atatctataa cacagctgag ttcatgaaga
     5401 acaacaacgc tccgatcaag gtagttggtt acgctgacaa gaagacgggt acttctgatt
     5461 ataacatggg tctttctgag aaacgtgcta gagcggtcgc taaggaactt atcgataaat
     5521 acggtatctc ttctagccag atcactatcg agtggagagg ttcggacgaa caaccttatg
     5581 gcgaaaatag ctggaaccgt gtagtaatta tgagcgctaa taattaattt acgaattaat
     5641 actttaaaaa ggccgtactt ctaagtgcgg cctttttttt gcgccgaaaa atacttactt
     5701 ttgtgagaat ttatcgaatt gctatgatat tgaacaaaaa acatggttat ttaatccaat
     5761 ggctgattgg tgtaggagat ttgatcgtat tgaatctctt gtttatggcc gtttttcatc
     5821 tgcttggccc gaaatacacg gaagcgatat cctataattt gagagaggtt attttgttat
     5881 tgaatttctg ttatttcttc tctttatatt ttatcccgat tcaattgcat caggcggtcg
     5941 tgtttatcga caagattgtg caacgggcgt tcggattggt taccgtactt atctttttat
     6001 tcgctacttg cttgatcttc ttgaatgtag gggatattct ggctaccttc ctcttggtct
     6061 attacggggt ttctatcatc ttgttttcgc tttggcgggt ttttgtgcgc ttatccttaa
     6121 agttttatag gcgaaaaggc tataacttta agaaggtggt gattgtgggt gcgggaaaga
     6181 atggtatgga gctttaccaa gttatgaaag atgatttgag ctatgggttt agtgtaaagg
     6241 ggttctttga tgacaatgac tcgttgaaag acgttttacc taattatttg ggtaagacga
     6301 gtgaggtgga agcgtatgtg ctggagcatg atatcgatga gatttattgt accttgccgg
     6361 gtacgaacaa cggaaagatc gtacggcttc tgaatttcgc tgagaagaag atggtgcgct
     6421 tctatatcgt gcccgagttt taccgggatg taaagaagag tatggtgatg gaggtgatgg
     6481 aatcgatccc attgctgacg gtccgccggg agcctttgca atccgcctat aaccggttct
     6541 tgaaacgaac gttcgatata tttttctctt tggtgatttt gctcacgatt tatccgatcc
     6601 tgtacatcgt ggtcggtata atgatcaagt taagctcacc cggcccgatt ttgtttaagc
     6661 agaaacgtac gggattgtat gggcatgact tcgaatgttt taaatttcgt acgatgaagg
     6721 tgaacgcgca ggccgatacc ttgcaggccg tcaaggatga tccccggaag acccggatcg
     6781 gcgatttctt gcgccggacg aatttggatg agttccctca gttcgtgaac gtcttgctgg
     6841 gcgatatgtc cgtggtaggc cctcgtccgc atatgctgaa gcataccgag cagtactcgg
     6901 cgttgatcga taagtatatg gtgcggcatt tggtgaaacc gggagtaacg gggtgggcgc
     6961 aagtcaccgg ttaccgaggt gagaccaaga cgctggagca gatggaagga cgtgtgaaga
     7021 gagatgtgtg gtatatagag aattggacgt tcttccttga tttaaagatt attgtggtta
     7081 cggtactgaa tatgttcaag ggagagaaga atgcatattg atccgatttg ttgcacactt
     7141 tttgcggatt tgtgtaatct gtatttatat ttatgctata ttcgcgctcg atgggaagaa
     7201 taattgcaat agattacggc cggaaacgta cagggatagc cgctacggat attttacaaa
     7261 tgatcgctaa cggcgtggcg acagtcccaa gtggagaggt tgtgaaatac ctgtcggatt
     7321 acatatcacg ggaaccggtg gatttatttg tggtcgggct tccgaagcaa atgaacaatg
     7381 agccttctga gaacatgaag tatgtggagg cgttcgtgac ccatctgaaa aggacgatac
     7441 caagtatccc ggtaacttat tacgacgagc ggttcacgtc ggtcttagct cataaggcca
     7501 tgttggaagg cggtttaaag aaaaagaaac ggcaagataa aggattggtt gatgagatta
     7561 gcgccgttat tattttgcaa gcttatttag aaagtaaaaa atatcagtta taacttatga
     7621 ttttacccgt atttttatat ggtcagcccg tactaagaaa agaggctgag gatgtaccta
     7681 aagattatcc cgacttgaaa cagttggttg ccaatatgtt tgaaacgatg tataatgctg
     7741 atggggtagg gcttgccgct cctcaggtgg gcttgtctat ccgtttggtg gttatagacg
     7801 gtgatgtgat gggagatgac ttccctgaat gcaagggttt caagcgtgcg ttgattaatc
     7861 ccgagttttt ggaacgtagc gaggaggaaa tagctatgga ggaaggctgc ttgagcctgc
     7921 cgggtataca cgagaaagtg tctcgctcga aaacggttcg tgtgagatat tgggatgaga
     7981 attgggagga acacgaggaa gtggtggaag gtttcgccgc ccgtatcgtg cagcatgagt
     8041 gcgagcatct gacggggcat gtctttatcg acaatgtctc cgctattcgc cgtcaattga
     8101 acaaaggcaa attaaatagt attattaaag ggacggttcg ttgctcttac cgggcaaaag
     8161 ccgttggtaa ataataaatc tataaataat caatatgaca gatttaagta aaaacattga
     8221 ggccctcagg gaaaagaaag ccgttatcga gatgggcggt ggtgaggctg ctatcgaaaa
     8281 gcaagtggcg atgggtaagc ttactgcccg ggagcgtatc ttggctttgt tggataagaa
     8341 ctctttccat gagtatgaca tgttcgtgaa acacgatggc cgtgatttcg gtatggagaa
     8401 gaaggttctg ccgggtgatg gtgtggttac cggtacgggt acgatctttg gtgccccggt
     8461 ttgcatctat gcgcaggact ttacggttgc cggtggttcg ttaggtttgc agcatgctcg
     8521 taagatcacc aagatcatgg atcatgcgtt gaagatgaaa tgtccgatca tcggaatcaa
     8581 tgactcgggt ggcgcgcgta tccaagaagg tgttggtgct ttggctggtt atggtgaaat
     8641 attctatcgc aatacgatcg cctcgggcgt gatccctcag atttccttga tcctcggtcc
     8701 ttgtgccggt ggtgccgttt attctccggc gttgacggac ttcgtgtttg tggttgagaa
     8761 catctctaag atgtttatca cgggaccgaa cgttatcaag accgtgctgg gtgaggatat
     8821 ctctatggaa gaccttggtg gcgcacgtgt tcatgcggag actacaggta acgctcattt
     8881 ctatgccttg agcgagcaag aatgtttcga tcaggtgaaa cgtttggtta gcttcatccc
     8941 ttggaataat caggagcgtg cgaaagtggt tgagccgaaa gaaccgtccg ctatgctgaa
     9001 tatcgagcaa gtagttccgg cggacccgaa acaaccgtat gatgtgcgag acgttatcag
     9061 atgtatcgtc gatgactcgg acttcttgga gattcaagag ttgtgggccg ctaatattgt
     9121 gatcggtttt ggtcgtatgg caggagaaac ggtaggtttc gttgccaatc aaccgatggt
     9181 tttggccggc gtgcttgatt gtgatagcgc tgacaaggcc gctcgtttca tccgtttctg
     9241 cgactcattc aatattccta tcatcacgtt ggaggatatg ccgggttatc tgccgggcgt
     9301 agatcaagag catgcgggtg tgattcgtca tggggctaag gttctgtatg cgtattcgga
     9361 agctactgtt cctaagatca cggttatctt gcgcaaggcg tacggtggag gttatatagc
     9421 tatgaactcc cgtcacttgg gcgctgactt catgttcgct tggccgagcg cggagatcgc
     9481 tgttatgggt ccggaaggcg cagctaacat catattccgc aaggagatca tggaggcgga
     9541 agatcagaac gctatgcgtc aggagaaggt gaaagaatat atcgagaaat tcgcgaaccc
     9601 gtacgtggcg gcttccaagg gatttatcga ctctgtgatc gaaccgaaag aaacccgttc
     9661 attattgcta cacgcactga agctttccat tctaaaagag gaatacagac cggccaagaa
     9721 gcacggtttg cctccgttct aaattgatga gagtatggaa aagaaacacc agcaagaaga
     9781 atatgtagac tttgtggtga cggcacgtaa atataagacg ttgctgacag cgaagtataa
     9841 gagccgaccg atgtggcata agccgtcggc tggtgacgtg gtttctcatc ttcccggaac
     9901 gattatcaag attatggtag aggaaggaca ggctgtggag gccgggcaac ttctgctaat
     9961 ccatgaggcg atgaaaatgc agaaccgggt ggtcgctccc atatcgggag tcgttgtcga
    10021 gctcaatgta aaagagggcg ataagataac gaagaatcat ttaatggtaa aaatagagtc
    10081 taagtaagat aatttactta tttttgcctc tcaatcattt ttaataggat gaagaaggca
    10141 acactctttt tgatattaca gatatttacg atttcgcttt ttgcgcagat taatacggac
    10201 cgtgtattgg ccattggcag gaacgccctt tattttgagg attatgttct ttccattcag
    10261 tacttcaatc aggttatcaa atccaaacct tggttggcgg aaccctattt ttaccgtgcg
    10321 gtggcgaaga taaatctgga cgattttaag ggggccgagg aagactgtac tttatgtctt
    10381 cagcggaacc cttttttaac gcaagcgtat tacgctcgcg gcatcgcccg tcaaagccag
    10441 gagaaatacg acgaggcgat cgacgattac cagaaaggac ttgagttcaa acccgaggac
    10501 cgccagatgc tggtgaatat ggcggtggct tttatccaga aaaaagacta taacggggcg
    10561 gagaagacat tcgatgattt aatgaccgcc catccgaaat attccatgaa ttatatgaca
    10621 cggggcgcta tgtatctgga gaaaggggat acgttgaaag ccttggccga ttataataag
    10681 gcgatcgaga tggatcctta ttatgcgccg gcgtatggca atcgtgcgat ccttcattat
    10741 caaatggatg attacaagga cgctttggcc gatttgaacg aggctctacg tctggatacc
    10801 cgtgagagcg gatattatat taaccggggg ctagttcgtt atcagatgaa tgacttgaga
    10861 ggtgcgatgg ccgattacga tcaggtgatc agcatggata gccggaactt gatcgcacga
    10921 ttcaaccgag gtttgcttcg gttccaagtc ggggataata accgtgctat cgaagacttc
    10981 gatgtcgtta tccagcaaga gccagataac tatatggctt attacaaccg tgcgttgctc
    11041 cgtttcgaga cgggcgacta ccggggggcc gtgcaggatt acgacgtggt cttgaagcaa
    11101 tatcctactt tcctgccagg ctttgtgagc cgttcggaag caaagcgtaa gctaggggat
    11161 aacgtggggg cagaccgtga ttattgggca gccataaaga tggaggagca ggccaagaac
    11221 ggacagctcc cgaagacatc gtcttctagc tccaatacag cggtgaacgg agatgccaag
    11281 acggacgatt cggaggagaa tactcgtgag caatccgata agaatatcaa taagttcaac
    11341 cgcttggtgg tatacgataa ggagcaggag cgtaaaagta aataccaaag tgaggtccgt
    11401 gggcgtgtac aagaccggaa tgtccatgtg gatctggaac cccagtttgt cttgacctat
    11461 tacgagaagg cggatcccgt aaagaaactt gtttattacg acaagatggt ggaggattac
    11521 aatggccaga tggtcttgaa gcgtaaattg cgtatcacga acgaggaggc cgctttgact
    11581 gaggatcaaa tcgccgtgca ttttgcctcc atcgacgagt attcggcgga gatcgagcgt
    11641 gatccgaaca acgctaacgc ttattttggc cgtgcgatgg acttcatgtt ggtgcaggat
    11701 ttctcggagg cgatcaagaa tttctcggaa gcgatcgagc gagacccgtc gttcacgatg
    11761 gcttatttca atcgtgccgt ggaacgttat aagcaattga tgtacaccca atcccagcag
    11821 gctagcaagg atacgtacga cttgagtggc tcgggaatga acttgaatat tggtaagtcc
    11881 gcacagtcgc aggtaaacgc caacacctcg gtggacctcc ggagcgctat gctgaaggat
    11941 aataagcgag cctatgagca tgagcagatc atgagggatt acgatatggt gatcaagctg
    12001 aacccgggtt ttgtgtacgc ttactttaac cgtgcgaatc tgcgttgcgc ccagcgtgat
    12061 ttccgtgccg ctatcgttga ttacaacgag gcgatcgagc gggaccctga atttgccgag
    12121 gcttactaca accgtgggtt agcccgtctg tcgcaaggtg acgtgaaccg gggcatcgcc
    12181 gacttgagca aggcagggga attgggtatc tacaacgcct atagtatcat caagcgaatg
    12241 acaagccggt gataacgcaa attattcgag ttaaatgttt cgctgataga aaagaaatat
    12301 taactttgtg ggctgaatat aaagaatttt agagaataga atatgataaa gattacattt
    12361 ccggacaatt ccgtaagaga atatgcaaag ggaacgactg ctatgcagat agcggaaagc
    12421 attagttctc gtttggcaca ggaagtccta gccgcaagcg tgaatgggga ggtttgggac
    12481 ttaagccgtc ctatcaacga cgacgctacg gtgaaacttt tgaagtggga agacgaggaa
    12541 ggtaaacatg cgttctggca ttccagcgct caccttatgg cagaggcttt gcaggaatta
    12601 tatccgggta ttaaattcgg tataggtccg gcgatcgaga acggtttcta ttatgacgtg
    12661 gatccgggcg aggccgtgat caaagagggt gatttcgctg ctatcgaggc taagatgctt
    12721 gagctggtag ccaagaaaga agagatcaaa cgtcaggaca ttaccaaggc ggatgccatg
    12781 aagatgttcg gcgatagagg tgaagagtat aaaacagagc ttatcagtga gttggaagac
    12841 ggtacgatca ctacctatac gcagggttct tttacggact tgtgtagagg gccgcactta
    12901 ccgaatacct cttatctgaa agtagtcaag atattgagcg tagccggcgc ttattggcgt
    12961 ggcgatgaga aacgcaagca attggttcgt ttgtatggta tcactttccc gaaaaagaag
    13021 atgttggatg agtatctgac attgttggag gaggccaaga aacgtgacca ccgtaagatc
    13081 ggtaaggaga tggacttgtt catgttctcc gatacggtag gtaagggctt accgatgtgg
    13141 ttgccgaaag gtaccgcctt gcgtttgcgt ctgcaagagt tcttgcgtcg tatccaagct
    13201 cgttataatt atcaagaggt aatgtgtccg ccgatcggta ataaattatt gtatattacc
    13261 tccggccact acgctaaata cggaaaggat tctttccaac cgatccatac acctgaggag
    13321 ggtgaggaat acttcttgaa accgatgaac tgtcctcatc actgtatgat ctataaaaac
    13381 tctcctcgtt cgtataagga cctgccgttg cgtctagctg agttcggtac ggtttgccgg
    13441 tatgaacaga gcggagagtt gcacggattg acccgtgtac gtagctttac gcaggatgat
    13501 gctcatattt tctgccgccc cgatcaagta aagcaggaat tcttgaacgt aatggacatc
    13561 atctcgatcg tattcaagac gatgaatttc gagaacttcg aggctcagat ctccttgcgt
    13621 gacaaagtga accgtgagaa atatatcggt agcgacgaga attgggagaa ggctgagcaa
    13681 gcgattgtag aggcttgtga ggaaaaaggc ttgaaagcta agatcgaata tggagaggcc
    13741 gctttctacg gtccgaaact cgacttcatg gtgaaagacg ctatcggccg tcgttggcag
    13801 ttaggtacga ttcaggtaga ctataactta ccggaacgtt tccagttgga atatacgggt
    13861 gccgacaacc agaaacaccg tccggttatg atccaccgtg cgccgttcgg ttccatggaa
    13921 cggttcgttg ccgtattgat cgagcacacc gccggaaagt tcccgttgtg gttgactccg
    13981 gagcaggtat gtatcatgcc gatcagcgag aagtttaatg attacgcttg gcaaatcgca
    14041 cgtgagttag gtaatcagga aatccgtgct atcgtagatg accgaaatga gaagatcggt
    14101 cgtaaaattc gtgacaatga attgaaaaga atcccttata tgctcatcgt tggagaaaaa
    14161 gaagcagaaa atggtgaagt ttctgtaaga aaacagggcg aaggtgataa aggttcgatg
    14221 aaaattgcta cctttgcagc gcttttgaat ggcgaggtag aggaaatgat gaatcgctgg
    14281 caaaaaagta atgattaaat aactaataac gaggagaata aatctttttg aatgaagaat
    14341 gacaatctga aagaacagta tagaatcaac gaacgtattc gtgttcgtga agttcgttta
    14401 gtaggtgaca atattgaaac gggtgtttat ccgatcgctc aagcgctgaa aatagcggaa
    14461 gagcagggga tggatctagt cgagatttca ccaaatgctg cgccccccgt ttgtagagta
    14521 atcgactacc agaaattcct ctatcagcaa aaaaagcgtc agaaagagca aaaagcgaaa
    14581 tctgtgaaag tggtcgtgaa ggagattcgt ttcgggcctc agacagatga tcatgattac
    14641 aattttaaat tgaagcacgc taagggattt ttggaggaag gttcgaaggt caaagcctac
    14701 gtgttcttta aaggccgttc tatccttttc aaggaacagg gagaagtcct gctgcttcgt
    14761 tttgccaacg atttggagga ttatggaaaa gtagagcagt tgccggtatt ggagggaaaa
    14821 cgtatgatta tcatgcttac tccgaagaaa gcgggcactg gttcagcccc ggctgcggcc
    14881 gcagctccga aagttgtaaa gaaagtgatc acgacaccta agcctaaaag cgagggtgat
    14941 aagaaaacag aagaataaaa tccgtccctg atagaaggga ggttaagttt aataattaaa
    15001 atataattgg aaaatgccta agatgaagac taattccggt gccaaaaaga ggttcgccct
    15061 taccggatca ggaaagatca aaagaaaaca cgcttttaag agtcatatct taacaaagaa
    15121 gactaagaag caaaagagaa atcttactca cacgggtttg gtagctagtg ttgacgtaag
    15181 caacgtaaag cagatgcttt gcatgaagta atctttattc attaagcgag ttttataacg
    15241 atttttatta accgaatgca ttagcaatca agttcatcct aagagatgac gctaacattc
    15301 aaaacagatt agaattatgc ctagatcagt aaatcatgtt gcttcaagag caaaaagaaa
    15361 acggatttta aaactaaccc gtggttatta tggtgcacgt aagaacgttt ggaccgtagc
    15421 gaagaataca tgggaaaaag gtttgactta tgctttccgc gaccgtcgta acaagaaacg
    15481 taatttccgt gctttgtgga ttcagcgtat caacgctgcc gctcgtatgg aaggtttgtc
    15541 ttactctcgc ctaatgggtg ctttgcacgc tgccggtatc gagatcaacc gtaaggtttt
    15601 ggcagacttg gccgttaacc atccggaagc attcaaggct atcgtagcta aagtgaaata
    15661 agatttttgc tatatagtta ataaagagcc tccccgaaaa ggaggctctt tttttgttgt
    15721 ttttgtttgg ttatgtcgat acgattacat atctttgtaa caagaaaaag ataaacaggg
    15781 aatgagttaa gccgcacttg ttcgattggg aaactcatca gtttatttta attccgagac
    15841 atagctcttg tcgccaatgg cgggccgcgc ccttcggggt atgcttagca cggcggatta
    15901 caaaggtggc aaagcactca aatcctgtca tacggagttt gttcacatct acagtgcggc
    15961 tttttcaaat agggaagagg atctttaatt agattctctt cttttttatg cggttcacgc
    16021 aggtagtctc gttagctcat ataaggggtc agtccgaaaa ccctgtgggt atgttatgtt
    16081 aataagcgaa agtgaactat ctttgcgttc aaattaaaat tatttgtcca atgccttcca
    16141 atcgcaacct acataagtta ctacgagtca tcttccccga agttttaatg gagtatttcg
    16201 agatctccgg ttggcatgac gactctgtca aaattgaagt ttggcttgat gaaaaaaact
    16261 acatggaacg ttctgattac aagagtggaa ctgtgatttc acatggtttt actgatgaga
    16321 aagtgattca ggactttcct ctgcgtggca aacctgttta tctccacgta agacgtcgcc
    16381 gctggtatga caaagctaca ggggaaacgt tttcctatac ctacgatgat cttacggccg
    16441 aagggacgaa actcactcct gagttcgtcg cttttttaaa agaagaagat tgaaactacc
    16501 gtggctagca taagctccat agcagatgct tatggggtaa aggggaaaca gttaacctca
    16561 cagtacaagg ggtttatcag cgcatacaga cagtgggacc agttagatca tgcctcagaa
    16621 tatgtcctgt tcaaacagaa cataggtcct agcctttgta ttgacgagac ttctttgagc
    16681 tgcggagaat tatatactgt tgtcactaac cgtgcgggac gtggtggcaa aggtacactt
    16741 gtggccatga tacgtggcac gaagtctgaa gacgtcataa aggtgcttga aatgattcat
    16801 gtctccaagc gcaagacagt caaagaggtc actttggacc tttcgccgac catgatgcgg
    16861 attgtccgga cggctttccc aaacgccact atgacaaatg accggtttca tgtacagaag
    16921 ctcttttatg aggcaattga tgagctcagg attacttatc gctggatggc acgggattta
    16981 gagaacgatg aaattcagcg gtgcagagag caagatatag agtatgttcc gtttcggtat
    17041 accaatggcg atacccgtaa gcagctgctg gcaagggcta agcatgtact tgtcaagcat
    17101 tttagtaaat ggactgaatc ccaaagaata cgtgcggaaa tcatattcga acattatccg
    17161 gaattgaaat cagtttacga cttagccata gagttgacca atgtgtataa taagcactat
    17221 aacaaggatg tggcacgtgg aaagcttgcc ttgtggtaca ataaaataga aaagcttgga
    17281 tacggatgtt tcagaaccgt aacaaatacc atgcagaact attatgagac aatactaaac
    17341 tatttcgtta acagggaaac aaatgcattt gcagaatcat tcaatgcaaa aattaaagcg
    17401 ttcagagcac agtttagggg agtcggggat ataccattct ttatttttag attatgcaaa
    17461 ctaacagggt agatttaaca tacccacagg gttttcggac tgacccaaaa cagcgaaccg
    17521 cccgacaacc cggcgagagt tacggacgga caaaacaaaa aaagcctcga agcgttcatt
    17581 acaaacaact tcgaggcttt cctccgaggt tcctggcgga ttcgaaccgc cgtacatggt
    17641 tttgca
//
LOCUS       DBMDTB010000083        16989 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_1074_length_16989_cov_11.566556, whole genome shotgun
            sequence.
ACCESSION   DBMDTB010000083 DBMDTB010000000
VERSION     DBMDTB010000083.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 16989)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 16989)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16989
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1074_length_16989_cov_11.566556"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..1286)
                     /locus_tag="ACZPB4_12600"
     CDS             complement(<1..1286)
                     /locus_tag="ACZPB4_12600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099087.1"
                     /translation="MKKVVGLLAGLCLCAGCENEIPEPTASVVSAGKFVVDYTAAAGA
                     ATRVIHENQPKGVRINSLTYLLYSEEGTLEKRREIPGLDTDGESWPLRRENMSWEQRE
                     ALKDTLSQGEIYHAVFVANIDSAVCGWTGADGQPWSPLRETGTYETVYLQMPFQPFND
                     RNMFYVFTRDILSTDQGADRENPYNCPVVLRRAVTRTDFWFEKLPDWEEKTEGGDTEI
                     SGYPATCLLPEDIKNYFQSDFYAFVLSKYKDELSQPVVDETVEFLDALELYFSGQILI
                     SDFDLELKDKYTKYNARLYEIEGQIQGEGKFDFLDQINSDMAEGGVLSNFQTHLVNTL
                     LNELEYNTTVRSLFEQSAKRKSGTWATIAYEGQSGVDKYYLSGKAPEAALAESLRMKA
                     DTIVMRKSVSYLAFNWVGLADPEKNKISGVSWYPTA"
     gene            complement(1314..2363)
                     /locus_tag="ACZPB4_12605"
     CDS             complement(1314..2363)
                     /locus_tag="ACZPB4_12605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099088.1"
                     /translation="MNKTIGKYICAWAVVCLAGCSNEVPQEGQTAVASFHVATRAADN
                     TAEREITDQQFVRLYVAERRPESGTPEATDPSDQYWDRYNVVLYCDKYYDLEGQTYHV
                     ENLPGVWHKFAFVCVPDISQGMGSGMFPAQNTFLTYKDLYDFAIDYRPVLDYQAALNE
                     ASKEDLAIYRKIIDRWVDTDMPTNERVLMRRVTGQLVLNMGKPADQFDTATNGAVTDI
                     TVSMKTARNCYIRDESCDSVLVIEREQREFHWTVSAEGQLEEQLLPIALLPGELSDAK
                     VTVSFADGTSVEYVLRGRAEEDVPMDAIEIKKNTRTIVLFNGKDKETFEVRYAGFADG
                     NDATVDVDDDAWDGV"
     gene            complement(2386..4788)
                     /locus_tag="ACZPB4_12610"
     CDS             complement(2386..4788)
                     /locus_tag="ACZPB4_12610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4906 domain-containing protein"
                     /protein_id="HIR1099089.1"
                     /translation="MKRYTWIWIMLIALLSGCEDDFDRGGSNPGEGVTEGMITFRFST
                     EEAPVIVTRAGEAGQQESLENVLVMVFDKDGKLVNKAYQQLTVDNHSVNIYLTAVADQ
                     SIYALCNLPEGDETEDLIDNSPVTLTKLKAKYTTIRTPEGAYGGKHITTGSLPLELTA
                     TGQLKKEYTIPVKRLTAQVNFNVSFEPYDPEDKFAVGEMFLYNIPMGSMLLDGGGSVD
                     DAGSWGYRHPNDALSDSLDICAGDYSYVVAGNAAETDRSAQFYQEGKRLDFEIVKGAV
                     GTNDTYTASFKMFENRQGRVYDHEENWENLKGLIGKDPETAGKYGYGDLYRYYQQINK
                     RGLAGTSRNPDDAEKIFKRNEDINDGKYTVNAKERGFKYATYLMIRGVYTKKNPVGGE
                     DPSNVTYYIYLGSDNYKDFNVCRNHVYNYRIRIFDADKTDTRVDANPIGGLTIYGNFE
                     DVLDAHPNVTQVLLYSPSNWTVRVADPDQTPWLEVSASPSYKPRKLGAEASRDQAAFR
                     LDGEAGLHYFYIHTDEYIPPINNPHGNDSNPRTGKLLFSNQAGNVKEVEIKQYAAQMV
                     IRERFATDLAKNVLDTLYVERILEKKNMQWGFQHYWCLKMDEILADDLNSKKNGLTNT
                     RVLYDIALNGDKWGIDPAYPDGNIPSNIALGYALGKNRDRNGNGKIDYNEILWYLPAY
                     TELQAIAGHISEGSRSYPREYSQTVDVDWEMEPYSFFSSTPSSSDAAGITAGFSWAVQ
                     FSPNPQKNGKARVEMRSRFYNVICARRYNGWRGPDTGTVDGEIDTDEDWNEDEEEIMD
                     KK"
     gene            complement(4799..7135)
                     /locus_tag="ACZPB4_12615"
     CDS             complement(4799..7135)
                     /locus_tag="ACZPB4_12615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008781094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099090.1"
                     /translation="MMKHVSILILIFLACLFAGCADEPIDSPEGLPEKGIVVRLTTGQ
                     LDTKTHLYSQASLHHVTQIYAILYYCGDMTADDIDPEKTKVVASQLLMKNGTPWDPSV
                     EEGYGQGQPQTETFELLLPQDQIAMVPGKYMILCVGLDDASGDTYGLTYGDDAANKQP
                     EFAKPGAKLSAAQAVLAKEAPSEPMPYEEDPTTAATDKKQDKELIAYGHPDIAHSELF
                     AGWRAFDFMPDNLNVVEVELRRRVAGVLCYLSDIPYKLNIGNTPYRVTEVRLNLFQQQ
                     NARIGLTREMTREGKPSLQDFGGPVDGKLVCQTLCKFDLMSFKSRPEQTGSGDLLYSI
                     PTSHLEGRKQLENTILMGAYALPIQNNTPDATLNVELWGYEYDDTPGSDDQIVAGSEL
                     TRIKSFPAIYEGKESTPEIYSLHPNMIYHIGHKLEGDNTEGDYPESLAGTKVTVEAGP
                     WQEVDIPVEFPSVPIVPLMSLRDKDGNKYKVEPEEAGEKYYIFDCIGSRTNHLEISAS
                     ILYENWKLTAVPVGDASDTPWIRFWDEMTNGYVTELTGTGGKDIYIRMADYASVPDWE
                     NKRETRRIRLLLEALDENGSVVGGASSDLYVEQYNALIVTLEDDSDGYRGFSRFDFGT
                     KRNAVTGDIVAAGQTLGWGYWRSLVVTEHWTDGKANYREFINKTWIDDFKGSAIQVCA
                     LGEAGKELEIDYEEAKSEDPFWFLPSIVALRCFLKQYKDNADANIEQGKFYWSSNSAG
                     SYKNALATKIDRSGNVDDNYYRENKENAYYARQACHAQ"
     gene            complement(7350..8846)
                     /locus_tag="ACZPB4_12620"
     CDS             complement(7350..8846)
                     /locus_tag="ACZPB4_12620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099091.1"
                     /translation="MKKNYFFGAVALCGLLAFTSCGNDDDPILDGPGNEVATGEQVIV
                     LDMQDTDVLSTKSRPLYSTDNRGSEDVTDVMLYIFKEETGTQKLIKTIHVDNWDNTCE
                     EYKYGRKRTIKLEGKDKLEAGSTYTIYAVGQNETEVEGNPAPFKFQGAVTAPGDDSWK
                     NIPGLLITNPSNITHNFATTPGSGFPYLLTKPVKYAKDTKFASRAVGEVFSGQSKPVT
                     LEPKESVSWTVLLKRQVAGVLGYFSNIPADGNALSDGTTACWSTKLRLVASNRNDRLD
                     MTIQLNKQNDDATEVGKENIVNGFSDSALDKDAEFKEGTDNAYTVYEINLEDWFTMGE
                     KGWTDVIEDTGDNNNKKYLGKTSGWKNPYEGTNAAVTVADGAVLAGEFVIPFDKDETL
                     NTFELQLMGKKKGTDTSFDTNDDKEYILQTWSVKLDDASIDATLKDTEYHYSIYRNHL
                     YQIGKRGGGDDPDKPGVDPDKPQPLDKSQELVIKINDQWEFIHDLEID"
     gene            complement(8895..9815)
                     /locus_tag="ACZPB4_12625"
     CDS             complement(8895..9815)
                     /locus_tag="ACZPB4_12625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008781096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099092.1"
                     /translation="MMERKHLHGITLLGGLAMALLCGCIRDELEPCPPLRLSLEVADK
                     NYVNSAAAARLGYEEERPEDLPFREYVSDLAYRVSDLETGRVVAERALSPVEGDAGSV
                     EVPLPADLPYGSYVLTAWGNLGDTAAFDSDLASLGLHPGGAEGSDAYFTRDTLVYALD
                     SERFSCGMRRLKGKLILATERMPEAYAFSEWKVSDIMSRFSAEGGYREPTTLAFDRSW
                     EREEPAMVAKSLLAPSRKRGASQVDLRYHVGDRPSEGGNWIAPEPVCVTMSRNELTIL
                     RYEYDPCCCRFKIFILINDNWETLHIMDVE"
     gene            complement(9812..11125)
                     /locus_tag="ACZPB4_12630"
     CDS             complement(9812..11125)
                     /locus_tag="ACZPB4_12630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008781097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099093.1"
                     /translation="MRFHSQKLLVALFSLGIFESCSPVKTPVGVSVSPRLGEVMLDPS
                     SKGTVKMKFQVPVDYLSKRGRLLITPRLVAPDGEVADMYEPVAVDAPVYVKKIYRKKV
                     LEGYVDSLPGQVVRADRWSELMEIPYETRVAVPEGWDDAYIDALVSVEGCASCGIIDT
                     LFVAKLRQSEPVDTFSLQWIRPTLAKRPKVMEGKGIAVLQFTINRSDIDGSLGDNRAE
                     LEKMAKTLRPILEDSLASVHSIHIIGMASADGPFGFNTNLAYQRAVAAGRWLQDRMAI
                     APEMKERILADVRPEGWEPVLEAMRQAGDPDAADVEAILERYPADGNNDDVQEREIRR
                     LSCWERIRTNYLQRDRKVEYRYTYTLKSFTSDEELLRMYATRPDAFSEEEFFRVAELM
                     PSLAEKIEAYRKLLAYYPASEVGKNNLTVLEHEWQMTNSRKGGVK"
     gene            complement(11130..11669)
                     /locus_tag="ACZPB4_12635"
     CDS             complement(11130..11669)
                     /locus_tag="ACZPB4_12635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009127779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3575 domain-containing protein"
                     /protein_id="HIR1099094.1"
                     /translation="MMRYKFLLFFLLVLWVAQTAKSQDVALKTNTLMWATTTPNLGLE
                     VALSPRYTLELSGSYNPWTFKDDKKMRFWLVQPELKYWFCEKSEGHFVGMHLHGAQYF
                     GGFKKKRYDGYLAGGGFTYGYDWILSPHWNLEAAIGIGYARLWYEESPRVYCEKCGED
                     KHKNYFGPTKAALSLIYIF"
     gene            12437..12919
                     /locus_tag="ACZPB4_12640"
     CDS             12437..12919
                     /locus_tag="ACZPB4_12640"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099095.1"
                     /translation="MVTKVRFMYFLLMYIMLIFSSCGDDGNEDWENGDKNTSQTEFKL
                     SPPDWLIGTWKNGDGLGMLTFQCTKDNIIYGLDGASMNFVKHAQESAAFYNQSNPPLG
                     DVKLYEELRGNNNYKVVLSITQMGVENKIFVEISKISSTEIYINTEEYNSQTKFTKVR
                     "
     gene            12916..13620
                     /locus_tag="ACZPB4_12645"
     CDS             12916..13620
                     /locus_tag="ACZPB4_12645"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099096.1"
                     /translation="MRKILYAIAFLFLVVSYSYSQGRTQDVVYLKNGSVIRGLIIEQV
                     PNKSIKVQTRDESIFVYQMDEIEKLGKEEDTSYSFKKILGPKRTYDIKGYRGFLDLGY
                     TTGDDGCIQFTTSHGYQLNPYFFFGAGTGVSYFTDSESALIPVFADLRGNFTNGQIVP
                     FIGLRIGYAIDVTSDYGGNGFYCNPFVGVKYMLGKQSAVNFSLGYGSQARRYSFRGHS
                     SSKSIDGFNFKIGIEF"
     gene            13703..14128
                     /locus_tag="ACZPB4_12650"
     CDS             13703..14128
                     /locus_tag="ACZPB4_12650"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099097.1"
                     /translation="MKRIIYLLAISCFLLISCHDDDRFSVENVVGNNTSIVGMWLREA
                     GKEQMVYAFFEDGTGYEKTTDRRNNTVSVDGFTYEFDPNTMSIVFDKEFDNAIYSEWT
                     VEMKGKSYMILTHHGIWDAGHGLTHEDTYSFELFRIMDE"
     gene            14222..14377
                     /locus_tag="ACZPB4_12655"
     CDS             14222..14377
                     /locus_tag="ACZPB4_12655"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099098.1"
                     /translation="MKKEEKKFVTEYQINGKKYAGEIWATSWEEAESFIKQRASTEKV
                     VGFIPKD"
     gene            complement(14374..14556)
                     /locus_tag="ACZPB4_12660"
     CDS             complement(14374..14556)
                     /locus_tag="ACZPB4_12660"
                     /inference="COORDINATES: protein motif:HMM:NF019057.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegP family protein"
                     /protein_id="HIR1099099.1"
                     /translation="MVKKTNQRRDKTTLYQDSNNKWRWRRTAPNGEIVGASTQGYANK
                     NDCKKNAIRNGCDIDD"
     gene            14716..15645
                     /locus_tag="ACZPB4_12665"
     CDS             14716..15645
                     /locus_tag="ACZPB4_12665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005825889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1595 family transposase"
                     /protein_id="HIR1099100.1"
                     /translation="MFEMNHFKSIDELVKFFPTEQSCIDFLERQRWGDHVVSPYDPDS
                     KVYKCKGNRYKCKNTGKYFNVRTNTIFENTKVSLRKWMLACYIVINAKKGVSSVQLAK
                     FINVTQKTAWFMLQRIQNCFNIDASQCLNGEVEVDETYIGGLNKNRHSSKKVRNARGR
                     SCKDKVPVFGMLQREGFVIAKVVNDTKAGTLIPIINDVVCPGSTIFSDEWQAYRNLDP
                     NLYDHGVVYHKKGAYVIGNRHTNTIEGFWGHLKRTLKGVHHWVSRKHLQRYVDSSAFR
                     YNTKHLSECERFDVLLQNIGHRLRYSQLKNMAA"
     gene            15642..15827
                     /locus_tag="ACZPB4_12670"
     CDS             15642..15827
                     /locus_tag="ACZPB4_12670"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099101.1"
                     /translation="MRKKKDIEVVIHKDIEKEMKRIADNIFGYNPKIDPRDPLFRKTL
                     SWSVKKEGKGKKNEKND"
     gene            15912..16793
                     /locus_tag="ACZPB4_12675"
     CDS             15912..16793
                     /locus_tag="ACZPB4_12675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HIR1099102.1"
                     /translation="MKSRRNISNDLKYTKEHFVCENYISDERSILEPIEVKGGEYLIR
                     EEVERFTLGFILSGEMDISTAGSVCQRVGEKQMFLIAAGDNFHGRAITDISLMRCSFT
                     RDMSLCNRFSIEQLQKYIPLGFQQEKCGITLLPIHELLFKELEVTREIMRTGMSCIHY
                     QRIKKEMLFIELRGFYQKEDLARFFAPILGTDNDFKENVLQIYPQVETAQELIDRLNM
                     SPSAFKRKFRETFGISARQWLIRKKEQKLIRDILMTNISIAELAEKYKFTANYMTTFC
                     RKRFGKSPTELRLEHKK"
BASE COUNT         4439 a         4263 c         3700 g         4587 t
ORIGIN      
        1 tcagccgtag gataccaact gaccccggaa atcttattct tttccggatc cgccaatccg
       61 acccaattga aagcaagata agaaacgctc ttccgcatca cgatcgtatc cgctttcata
      121 cgcaggcttt ctgccagagc tgcctccgga gcctttccgg acaaataata tttatccact
      181 ccagattgtc cctcgtaagc aatcgttgcc catgttcccg attttctttt tgctgattgc
      241 tcaaacagac tacggacggt tgtattatat tcaagttcat tcaacagcgt attaaccaaa
      301 tgggtttgga agtttgataa aacaccgcct tccgccatgt ccgaattgat ttgatctaaa
      361 aagtcgaatt tgccttcgcc ctgaatttgc ccttctattt catataaacg cgcattatat
      421 tttgtgtatt tatctttcaa ctcaagatcg aaatccgaaa tcagaatctg tccggaaaaa
      481 tacagctcca aagcatccaa aaactcaacc gtctcatcaa ccaccggctg gcttaactca
      541 tctttatatt tcgacaagac aaaagcatag aaatccgatt gaaaatagtt ctttatatct
      601 tccggtaaca agcaggtagc cggataaccg gatatttccg tatccccccc ctctgtcttt
      661 tcttcccaat caggaagttt ctcaaaccag aagtcggtac gggtcaccgc acgccgcaac
      721 acgaccggac aattgtaagg attctcccga tcggcacctt gatccgtcga caagatgtcc
      781 cgcgtgaaaa cataaaacat attccggtca ttgaacggct ggaagggcat ttgcaaataa
      841 accgtctcgt acgtcccggt ctctcgcagg ggagaccacg gctgaccgtc cgcacctgtc
      901 cacccgcaaa cggcggaatc gatattggcc acaaagaccg catgatagat ctcaccctgc
      961 gacaaggtgt ctttcaaagc ctcccgttgc tcccacgaca tattctcgcg tctcaacggc
     1021 caactctccc cgtcggtatc caacccgggg atttccctcc gcttctccaa cgtcccctcc
     1081 tcactataca gcaggtaagt aagcgagttg atacgtaccc ctttcggctg gttttcatgg
     1141 atcacacgcg tggcggcacc agccgcggcc gtgtaatcca ccacgaactt accagccgaa
     1201 accaccgatg ccgtaggctc cggtatctca ttttcgcatc cggcacaaag gcataagccg
     1261 gctaacaacc ccacaacctt tttcatatat acgattccat tcattattca cattcatact
     1321 ccatcccatg cgtcatcgtc gacatccacc gtcgcatcgt ttccatcggc aaaaccggcg
     1381 taacgcacct cgaacgtttc tttatcctta ccgttaaaca agacaatcgt ccgtgtattc
     1441 ttcttgattt cgatagcatc catcggtaca tcttcttcgg cacgtccacg caagacgtat
     1501 tctaccgagg taccatccgc aaaagagacc gtcaccttgg cgtctgacag ttcccccgga
     1561 agcagggcga tcggtaagag ctgttcttcc aactgtcctt ccgcgcttac ggtccaatga
     1621 aattcccgct gttcacgctc gataacaagc accgagtcac acgactcgtc gcggatatag
     1681 caattccggg ccgttttcat gctgaccgta atatccgtca ccgccccatt cgttgccgta
     1741 tcgaactggt cggccggctt tcccatattc aggacgagtt gcccggtgac gcgtctcatc
     1801 agcactcttt cgttggtcgg catgtcggta tcgacccagc ggtcgatgat tttacggtaa
     1861 atcgccaagt cttccttgct cgcctcattc aacgcggctt gatagtccaa taccggtcgg
     1921 tagtcgatcg cgaaatcgta aaggtcctta tatgtcaaaa acgtattttg agccggaaac
     1981 atcccgcttc ccatcccttg gcttatatcc ggcacgcaca cgaaagcaaa cttatgccaa
     2041 actccgggca aattctcgac atgataggtt tgtccctcca ggtcataata tttgtcgcaa
     2101 tacaagacca cattataccg atcccaatat tgatccgaag gatcggtagc ctcgggggtc
     2161 ccgctttccg gcctgcgttc cgccacatag agccgtacaa actgctgatc cgttatctcc
     2221 ctctcggcgg tattgtctgc ggcacgtgta gccacatgga atgaggcgac cgccgtttgc
     2281 ccttcttgcg gaacctcatt cgagcatccg gcaaggcaaa ccaccgccca agcgcatata
     2341 tattttccta tcgtcttatt catcgcgtct aatccttttt tcccactatt ttttatccat
     2401 gatctcttcc tcgtcctcat tccagtcctc gtccgtatcg atctcgccgt ctaccgttcc
     2461 cgtatcgggc cctcgccaac cgttatagcg gcgggcgcaa atcacgttgt agaaacgcga
     2521 gcgcatctcg accctcgcct tgccgttctt ttgcggattg ggcgaaaact gcacggccca
     2581 actgaacccg gcagtaattc cggccgcatc gctagacgag ggcgtggagg aaaagaagga
     2641 ataaggttcc atctcccagt ctacatccac agtttgtgag tattccctgg gataagacct
     2701 cgacccttcg ctgatatgcc cggctatcgc ctgcaattcg gtgtaagccg gcaaatacca
     2761 caaaatctcg ttatagtcga tcttcccgtt gccgttacgg tcgcggttct tgcccaaggc
     2821 gtatcccaac gcgatgttcg atggaatatt gccgtccgga taagccggat cgatgcccca
     2881 tttgtcgccg ttcaaagcga tgtcatacaa cacacgggta ttggtcaacc cattcttttt
     2941 cgagtttagg tcgtctgcaa ggatctcatc catcttcaga caccaataat gctggaatcc
     3001 ccattgcata tttttctttt ccaagatacg ttccacgtag agcgtgtcca gtacattctt
     3061 cgcgagatcc gtggcaaacc tctcgcgtat caccatctgg gccgcgtact gcttgatctc
     3121 tacctctttc acgtttcccg cctggttcga gaacaggagc ttgcctgtac gggggttgga
     3181 atcgttaccg tgcggattgt tgattggcgg gatatactcg tccgtatgga tatagaagta
     3241 gtgcaacccc gcctctccgt ccagacggaa agcggcttga tcgcggctag cctccgctcc
     3301 cagcttacgg ggcttatagg atggcgaggc ggaaacctcc agccaggggg tctggtccgg
     3361 atcggccacc cgcaccgtcc agttactggg cgagtagaga agtacctgcg tcacgttggg
     3421 atgggcatcc agcacgtcct cgaagttccc gtagatagtc agcccgccga tcggattggc
     3481 atccacgcgg gtgtcggtct tgtccgcgtc gaagatacgg atccggtagt tatagacatg
     3541 gttacggcag acgttgaagt ctttgtaatt gtccgaaccg aggtagatat agtaggtcac
     3601 gttgctcgga tcctcgcccc ccaccggatt cttcttggtg tagacaccgc ggatcatcag
     3661 gtaggtggca tacttgaagc ctcgctcttt cgcattgacc gtatacttac cgtcatttat
     3721 gtcttcgttt cttttgaata tcttttcggc atcatccgga ttccggcttg tcccggcaag
     3781 cccccgcttg ttgatttgct gataatagcg atacaaatcc ccataaccat actttccggc
     3841 agtctcggga tcttttccga tcaatccttt caggttctcc cagttctcct catggtcgta
     3901 cacccttcct tgccggttct cgaacatctt gaaagaggca gtataggtat cattcgttcc
     3961 aaccgctcct tttacgatct cgaagtccaa tctttttccc tcttggtaaa attgtgccga
     4021 acggtctgtc tcggcagcat taccggccac gacatacgaa taatcgcctg cgcaaatatc
     4081 cagcgaatcc gacaacgcgt cgttgggatg acgatatccc caactacccg cgtcgtcgac
     4141 cgacccgccg ccatccagca gcatgctgcc catcgggata ttgtaaagga acatttcccc
     4201 gaccgcgaat ttatcttccg gatcgtacgg ttcgaaagag acattaaaat tgacttgcgc
     4261 cgtcagacgt ttaaccggga tggtgtattc ctttttcaac tggccggtcg cggtcagttc
     4321 caacgggagg gagccggtcg tgatgtgttt gccgccataa gctccttccg gagttcggat
     4381 cgtggtatat ttcgccttca acttagtcaa agtgaccgga gagttgtcaa tcaaatcttc
     4441 cgtctcgtct ccttccggca aattgcacag ggcatagatg gattgatccg ccacggcggt
     4501 caggtagata ttgaccgaat ggttatcgac cgtcaattgc tggtaagctt tattgaccaa
     4561 tttcccatct ttgtcaaaca ccatgaccaa cacattctcc aaagactcct gctgcccggc
     4621 ctcaccggcc cgggtaacga tcaccggcgc ctcctcggta gaaaagcgga aagtgatcat
     4681 cccttccgtt accccctcgc ccgggtttga gccgcccctg tcgaagtcgt cttcgcaacc
     4741 ggacaacaag gcgatcagca tgatccatat ccaagtatat cgtttcatat cgctatattt
     4801 attgtgcgtg acaggcttga cgggcataat acgcattttc cttattttct ctataataat
     4861 tatcatcaac attgcctgaa cggtcaatct ttgtcgctaa tgcgttttta taagaaccag
     4921 cagaattaga actccaataa aattttcctt gttctatatt cgcatccgcg ttatccttat
     4981 attgcttcaa gaaacatctc aatgcgacta tcgatggcaa gaaccaaaaa ggatcttcag
     5041 acttcgcttc ttcataatct atctcaagtt cttttcccgc ttctcccaat gcacaaacct
     5101 gtatggcaga gcctttaaaa tcatctatcc atgttttatt tataaattcc cgataattgg
     5161 ccttaccatc tgtccaatgc tctgtcacaa caagagatct ccaatatccc catccgagtg
     5221 tctgtccggc agccacgata tcccctgtaa ccgcgtttcg tttcgtccca aaatcgaaac
     5281 gactgaagcc acgatatccg tcactatcat cttccaatgt cacaatcaac gcattgtatt
     5341 gctccacgta caaatcagag gaggcaccgc ccaccacaga accgttttca tcaagggcct
     5401 ccagcagtaa tcggatcctc cgtgtctctc gcttattttc ccaatccggg acactcgcgt
     5461 aatcagccat ccgaatgtaa atatcctttc ctccagtacc agtcaattca gtgacataac
     5521 cgtttgtcat ttcgtcccaa aaccgaatcc aaggcgtatc cgaagcatca ccgaccggta
     5581 ccgctgtcag tttccaattc tcataaagaa tcgatgcgct tatctccaaa tggttcgttc
     5641 gcgaaccgat gcagtcgaaa atataatatt tctcgccggc ctcttccggc tcaaccttat
     5701 acttattgcc atccttgtcc cgcagagaca tcaagggaac aataggcaca ctgggaaatt
     5761 ccaccggaat atccacttcc tgccaaggtc cggcctccac ggtcaccttg gttcccgcca
     5821 ggctttccgg atagtcgcct tccgtattat ccccttccag cttatgcccg atatggtaaa
     5881 tcatattcgg atgcagggag tagatctccg gggtactctc cttgccttcg taaatggcag
     5941 ggaaagattt gatccgggtc aattcgcttc ccgcaacaat ctgatcatca ctacccggcg
     6001 tatcatcata ttcgtacccc cacagttcta cgttcagcgt ggcatcgggg gtattatttt
     6061 gaatgggcag tgcgtacgcc cccatcaaga tggtattctc cagttgtttc cgtccctcca
     6121 ggtggctggt tggtatactg tacaaaagat caccgcttcc ggtttgctcc ggtcgcgatt
     6181 tgaaactcat cagatcgaac ttacaaagcg tttggcaaac cagtttcccg tcaaccggtc
     6241 caccgaaatc ctgtagggac ggcttgccct cccgcgtcat ctcccgtgtc aggccgatcc
     6301 gcgcgttttg ctgctgaaag agattcaggc gtacctctgt tacccgatag ggggtattac
     6361 ctatattcag tttataaggg atgtccgaga ggtagcaaag cactcctgcc acgcggcggc
     6421 gcagttccac ctccacgaca ttcaaattgt cgggcatgaa gtcgaacgcc cgccaaccgg
     6481 cgaaaagctc cgaatgcgct atgtcgggat ggccgtaagc gattaattct ttatcttgtt
     6541 ttttgtcagt cgcggcggtt gtcgggtctt cctcataagg cataggttcg cttggggctt
     6601 ctttcgcgag aaccgcttgt gccgccgaca gtttggctcc gggtttggca aactccggct
     6661 gtttattggc ggcgtcatca ccataggtca ggccatacgt atcgcccgag gcgtcgtcta
     6721 agccgacaca taatatcata tatttgccgg ggaccatggc gatctggtct tgcggcaaca
     6781 gaagttcaaa cgtttcggtt tgcggctgtc cttgcccata gccctcctct accgagggat
     6841 cccaaggggt gccgtttttc atcagtagct gggaagctac gaccttggtt ttttccgggt
     6901 caatatcgtc cgcggtcata tcaccgcaat aataaaggat ggcgtagatt tgagtcacgt
     6961 gatgcaagct agcctggctg tacaggtgtg tcttggtatc caactgcccg gtagtcaacc
     7021 taacgacgat acccttctcg ggaagaccct ccggagaatc tatcggttcg tcagcgcaac
     7081 ccgcgaagag acaggcaagg aatatcagga ttaagatgct cacatgtttc atcatatcag
     7141 aaacttttct taaattactc gttcttgttt tgtataaata gacattataa ccggcccgtg
     7201 tgcttcctta catataaaaa ggggggggtg ccggggtgct tatagtttcc tgtctaggaa
     7261 actgaataga ggagccgtgc cttgtcggca cagctcccgt ataaaagtga ttgtccctta
     7321 tcaatcggga agtccgatgc gggcggacat tagtcgatct ccaggtcgtg gatgaattcc
     7381 cactggtcgt tgatcttgat taccaactct tgggatttat ccagcggctg tggtttatcc
     7441 gggtcaacgc ctggtttgtc gggatcgtcg ccaccgccac gcttaccgat ttggtacagg
     7501 tggttacggt agatgctgta atgatattcc gtatctttca gggtagcgtc gatagaggcg
     7561 tcatccaact taacagacca ggtctgaagg atgtattctt tgtcatcgtt agtatcgaag
     7621 ctagtgtctg ttcctttctt cttacccatc aactgaagct cgaaagtatt caaggtctca
     7681 tccttgtcga acgggatgac gaactcaccg gccaatacgg cgccatcggc tacggttacg
     7741 gcggcgttgg taccctcata cgggttcttc catccggaag tcttgccaag gtatttcttg
     7801 ttattattat cccccgtatc ctctatgaca tctgtccaac ctttttcacc catggtaaac
     7861 cagtcttcca aattgatctc ataaacggtg taggcgttat ctgttccttc tttgaattct
     7921 gcgtctttat ccaaagcgct gtcactaaaa ccattgacaa tattctcctt gcctacctcg
     7981 gtagcgtcgt cgttctgctt gttcagctgg atggtcatat ccagacggtc gttacggttg
     8041 gaagcgacca aacgcaattt ggtagaccaa catgctgttg taccatcaga taaagcattt
     8101 ccatccgccg ggatattcga gaagtaaccc agcacaccgg caacctgacg cttcagcaac
     8161 acggtccaag agacactttc cttcggttct aatgtcaccg gtttggattg accggagaat
     8221 acctcgccga cagccctgct ggcgaatttc gtatctttag catacttaac aggctttgtt
     8281 aacaggtaag ggaagccgga acccggagtg gtggcgaagt tgtgggtgat gttgctagga
     8341 tttgtgatta aaagccccgg gatatttttc cagctatcat cacccggagc agttaccgca
     8401 ccttggaact tgaacggagc cggattgcct tccacctctg tctcgttctg gcctacggcg
     8461 tagatcgtat aagtcgaacc agcctccaac ttatccttcc cttccagctt aatggttctc
     8521 ttacggccat atttatattc ctcgcaagta ttgtcccagt tgtccacatg gatggtctta
     8581 atcaacttct gtgttccagt ctcctctttg aagatataca gcatcacgtc cgtcacatcc
     8641 tcggatcccc tgttgtccgt actatacaag ggacgagact tcgtgctgag cacgtccgta
     8701 tcttgcatat ccaacacgat tacctgttca ccggtggcaa cctcgttacc cggtccgtcc
     8761 aagataggat cgtcatcgtt gccacaagaa gtgaacgcta acagaccgca caaagcgacc
     8821 gcgccaaaga aataattctt tttcatttgc ttcttctttt aaatgttaaa cttcggtttt
     8881 atctataaat aacgttattc cacatccatg atatgcaggg tctcccagtt gtcgtttatc
     8941 aagatgaaga tcttgaaacg gcagcagcag gggtcgtact cgtagcgcaa gatggtcagc
     9001 tcgttgcggc tcatcgtcac gcagaccggc tccggggcga tccagttgcc gccctccgag
     9061 ggcctgtcgc ccacgtggta gcgcagatca acctgcgacg cgccccgttt ccgggagggg
     9121 gccaacaggc tcttcgccac catggccggc tcctcgcgct cccagctacg gtcgaaggcc
     9181 aacgtcgtcg gctcgcgata gcccccctcg gcactgaaac ggctcatgat atccgatacc
     9241 ttccactcgc tgaaggcata cgcctcgggc atcctctcgg tagccaggat caacttgccc
     9301 ttcaagcgcc tcatgccgca cgagaaacgc tcgctatcca aggcatatac cagcgtatcg
     9361 cgggtgaaat aggcgtcgct accctccgcg ccgccgggat gcagccccag cgaagcgaga
     9421 tcgctgtcga aagccgcggt atcgcccagg ttgccccagg ctgtcagcac gtaagagccg
     9481 tagggaaggt cggccggtag gggcacctcc acgcttcccg cgtcgccttc cacgggtgac
     9541 agcgcgcgct cggccacgac acggcccgtc tccaaatcgc tcacccgata ggccaagtcc
     9601 gacacatact ccctgaaggg aagatcctcc ggacgctcct cctcgtaacc caagcgagcc
     9661 gccgccgcgc tgttgacata attcttatcc gccacctcta gcgagagacg caacggcgga
     9721 caaggctcca gctcgtcgcg gatgcagccg cacagcagcg ccatagccaa tccacccaac
     9781 agggttattc catgcaaatg ttttctttcc atcattttac gcctcctttc cggctgttcg
     9841 tcatctgcca ttcatgctcg agcacggtca agttgttctt cccgacctcc gaagccggat
     9901 aataagcaag caacttacgg tacgcctcga tcttttcggc caacgaaggc atcagttccg
     9961 ccacgcggaa aaactcctcc tcgctgaacg cgtccggccg ggtggcatac atccgcaaca
    10021 gttcctcgtc ggaagtgaaa ctcttcagcg tgtaggtgta acggtactcc accttgcggt
    10081 cgcgttgcag atagttcgtg cggatacgtt cccagcagga cagacgacgg atctcgcgct
    10141 cctgcacatc atcgttgttg ccgtcggcgg gataacgctc caggatagcc tccacatcgg
    10201 ctgcatccgg gtcaccggct tgccgcatgg cttccaacac cggctcccaa ccttcgggac
    10261 ggacatcggc aaggatacgc tccttcatct ccggggctat cgccatcctg tcttgcagcc
    10321 agcggccggc ggccaccgcc cgttggtacg caaggttcgt gttgaacccg aacgggccat
    10381 cggcagatgc catcccgatg atgtgtatgg agtgtacgct cgccaacgaa tcttccaaaa
    10441 tcgggcgtaa cgtcttcgcc attttctcca gttccgcccg gttgtcaccc agcgagccgt
    10501 ctatgtccga acgattgatg gtaaactgca agacggcgat cccttttccc tccatcactt
    10561 tcgggcgctt cgccagcgtg gggcggatcc attggagcga gaaggtatcc acaggctccg
    10621 attgccgaag cttagccaca aacaaggtat ctataattcc gcatgacgca catccctcga
    10681 cggagaccaa cgcgtctata taggcatcat cccagccttc aggaaccgcg acccgcgtct
    10741 cgtaaggtat ctccatcaac tcagaccaac ggtcggcacg gacaacctgt ccgggcaggg
    10801 agtcgacata cccttccagc acctttttcc tatatatttt cttcacataa accggcgcgt
    10861 caacggctac cggctcatac atatccgcca cctcgccatc gggtgccacc aaacggggcg
    10921 taataagcaa acgtcccctt ttcgacaaat aatccaccgg cacctgaaac ttcattttca
    10981 ccgttccctt gcttgaggga tcaagcatca cctcacccaa cctcggagac acggagacac
    11041 caacgggtgt cttgaccggc gagcaactct cgaatatccc caaggaaaaa agagcgacca
    11101 acaatttttg tgaatgaaat ctcataccgt tagaatatat aaatcaatga cagggcagct
    11161 ttggtaggcc cgaaatagtt cttatgtttg tcttctccgc acttctcgca atagacgcgg
    11221 gggctctcct cataccacag gcgggcatag ccgataccga tggcggcctc caggttccaa
    11281 tgcggcgaga gaatccagtc gtacccgtaa gtgaaacctc ctccggccag atagccatcg
    11341 tagcgtttct tcttgaatcc cccgaagtac tgcgccccat gcaagtgcat accgacaaag
    11401 tgcccctcgg acttctcgca gaaccaatat ttcaactcag gttgtaccaa ccagaaacgc
    11461 atcttcttgt cgtccttgaa tgtccaagga ttgtaggatc cggacagttc cagcgtatat
    11521 ctcgggctaa gagctacttc caatcctaga ttcggcgtag tggtcgccca catcaaggta
    11581 ttggtcttca atgccacgtc ttgcgacttg gctgtttgcg caacccacaa aaccaataga
    11641 aaaaataata aaaacttata tctcatcatt tattatttgt tttttgtccg ccttccggca
    11701 catgacactc tttcgctatc aggcgactga catatcggca gtggcataca gaacaacgct
    11761 tcttcgttct tacgaaatgc ggcctcccgc cgtatctatg catacttctc ttttccggtt
    11821 accctttcag agccttcctt ctagccatac acaaaaaaac ttaaaagttc ttcctcttac
    11881 aaagaggagg aacttttgtt gaaaaacgaa ctttgttatt gatatatagt gtattataat
    11941 aatacgctca tcagttccaa tgataaaaaa gcgatccctg ttctattttt tagtcaataa
    12001 ttataattaa agaaggtaat tatataccag tttacacctc cctataaaaa gatagacaaa
    12061 tctcattttt attgatcgcc cctatgataa agcattaaaa agtatgtcat agggttgttt
    12121 gcgtttctaa atatctatat ctttgcccca cgtattagaa taaagacgta gaagcgttaa
    12181 gatattatct cgtatttgaa atctggacaa tttcaaccac tcgggataat agacaaagat
    12241 gcctcctacg cctatgttgt tatatttata cctctagggg caaactatat acaatcataa
    12301 ggcgtggggc tgttgtttgt tatcgggtgg tgggcagtcc agagcctcaa atacggtaac
    12361 atccaatagt ccccacgctt cttttattta gaaaccaccg aacgaagggg acagggagga
    12421 taaaagcaat agatttatgg taacaaaagt gagatttatg tatttcttat tgatgtacat
    12481 aatgcttata ttttcatcat gcggagatga tggaaatgag gattgggaaa atggagataa
    12541 aaacacttcg caaacagagt ttaaactctc tccaccggat tggttgatag gtacatggaa
    12601 aaatggtgat ggactaggga tgttaacatt tcaatgtact aaagacaata taatatatgg
    12661 attagatggc gcttctatga atttcgttaa gcatgcccaa gaaagtgccg cattttacaa
    12721 tcaatccaat ccacccttag gagatgtaaa attgtatgag gaactacgag gtaataataa
    12781 ttacaaagtc gtattaagca taacccagat gggggttgag aacaagattt ttgtagagat
    12841 atccaaaata tcatctacgg aaatatatat taacacagaa gaatataatt cacaaactaa
    12901 attcaccaag gtaagatgag aaaaatacta tatgcgatag cctttttatt tttagttgtt
    12961 tcctactcct attcacaggg gagaacacaa gatgttgttt atctaaagaa cgggagtgta
    13021 atcagaggtc ttatcataga gcaagtacca aacaaatcca taaaagtaca gaccagagac
    13081 gaaagtatct ttgtctatca aatggatgag atagaaaaat tagggaaaga agaggataca
    13141 tcttattcgt ttaagaaaat attaggccct aagaggactt atgatattaa agggtatcga
    13201 ggatttttgg atttgggata tactacgggg gatgatggat gtatccaatt taccacatct
    13261 cacggatacc aattaaatcc gtatttcttc ttcggtgcgg gaaccggagt atcatatttc
    13321 actgatagtg aatcagcgtt aatccccgtt ttcgcagatt tacgagggaa ctttaccaat
    13381 gggcagatag ttccttttat aggattaagg attggttatg ccattgatgt cactagcgat
    13441 tatggtggaa atggttttta ctgtaatccc tttgtcggtg taaaatatat gcttggaaaa
    13501 caatcagctg ttaatttttc cctaggttat gggtcacaag ctaggagata ttcttttaga
    13561 ggacattctt ctagtaagag tatagacgga tttaatttca agataggtat tgagttctaa
    13621 ttgtgaatat tgataaatat taatattgta aaaataaatc tatcgtaata ctattttgcg
    13681 taatatcaaa aggagagtaa tcatgaaacg tatcatatac ttattagcga tatcatgttt
    13741 cctacttatt tcttgccacg atgacgatcg ttttagtgtc gaaaatgtag ttggcaataa
    13801 tacctctatc gtaggaatgt ggcttcgaga agcaggcaaa gaacaaatgg tatatgcgtt
    13861 ctttgaagac gggactgggt atgaaaaaac aactgataga agaaacaata ctgttagtgt
    13921 agatggattc acatatgaat ttgatccaaa tacgatgagt atagtttttg ataaggagtt
    13981 tgataatgca atatactcag agtggaccgt ggaaatgaaa ggaaaatctt atatgatcct
    14041 aacacatcac gggatctggg acgctgggca cggcttaaca catgaggata cttactcatt
    14101 tgagctattc agaataatgg atgagtagac taaacagtaa aattaaaaga taagcgggat
    14161 tagatttagg ctagtcccgc ttttgtttta tcatatttat taatttttaa aaattacaaa
    14221 catgaaaaaa gaagaaaaga aatttgtaac agagtatcaa atcaatggca aaaagtatgc
    14281 cggtgaaata tgggcaacct catgggaaga agctgaaagt tttataaaac aaagagcttc
    14341 taccgaaaag gttgttggat ttattcctaa agattaatca tctatatcac atccatttct
    14401 tattgcattt tttttgcaat catttttatt tgcataacct tgtgtagacg cacctactat
    14461 ttctccatta ggagctgttc ttcgccaacg ccatttatta ttagaatctt gataaagagt
    14521 agtcttatca cgtctttgat ttgttttctt taccataaca ttagatttta aagtttattt
    14581 tcaaatatag caatcttatt tctaaacaat cctaattaaa actaaaacaa ttttaatgag
    14641 attatattgg gggtatggtt tgattgctgg ttttgaacga atttattatc tttatagagt
    14701 aaaaatcaga gtgttatgtt tgaaatgaat cattttaaat ctattgatga gttagtgaag
    14761 ttcttcccta ccgagcaatc atgtattgat tttttggaga ggcagagatg gggcgatcat
    14821 gtcgtatctc catacgatcc ggactcaaag gtttataaat gtaagggaaa ccgttacaag
    14881 tgcaagaaca cgggaaagta cttcaacgtc cggacaaaca cgatcttcga gaacacgaaa
    14941 gtgtcgttga ggaaatggat gttggcttgc tatatcgtca taaacgctaa gaagggtgtc
    15001 tcttccgttc agttggctaa gttcattaac gtaacacaaa agacggcttg gtttatgttg
    15061 caacgtatcc aaaattgttt caatatagat gccagccaat gtctaaacgg agaggttgag
    15121 gtagatgaga cttatatagg gggattgaat aagaataggc atagtagtaa gaaggtaaga
    15181 aacgcaagag gcaggagttg taaggacaag gttccggtat ttggtatgct acaaagagaa
    15241 ggctttgtta tagccaaggt tgttaatgat actaaagccg gaactttgat tccgattata
    15301 aacgatgttg tatgtccggg atctacaatc ttctcggatg aatggcaagc ttatagaaac
    15361 ttagatccta acctatacga tcacggtgtt gtctatcata agaaaggcgc ttacgtcatt
    15421 gggaatagac atactaatac gatcgaagga ttctggggac acctaaaaag aacattgaag
    15481 ggtgtccatc attgggtgtc taggaaacat ctgcaaagat acgtggactc atcagctttt
    15541 aggtataata ccaaacatct ttccgaatgt gaaagattcg atgtactttt gcagaatatc
    15601 ggacaccgat taaggtattc acagttaaag aatatggcag catgagaaaa aagaaagaca
    15661 tagaagtagt aatacataaa gatattgaga aggagatgaa gagaatagcc gataacatat
    15721 tcggctataa tccaaaaata gatccccgtg atcctctttt tcggaaaact ctttcttgga
    15781 gcgttaaaaa agaaggaaag ggaaagaaaa atgagaaaaa cgattgaata ataaaaggat
    15841 acatggttat gtgtcctttt attattttag tgatagtgta aagtagtata taattacctt
    15901 aaagaaaaac aatgaaatcg agacggaaca tatccaatga tctgaagtat acaaaagagc
    15961 actttgtctg tgaaaattat atttctgatg aacgatccat cttggagcct atagaggtaa
    16021 agggcggcga atatctgata cgggaagaag tggaacgttt cacgcttgga tttattcttt
    16081 ccggggagat ggatatatcg actgccggat ctgtatgcca acgggtgggt gaaaaacaga
    16141 tgtttctcat agctgccggt gacaattttc atggaagagc gattacggat atctccctga
    16201 tgcgttgttc gttcactaga gatatgtcct tatgcaatcg tttctccatt gaacagttac
    16261 aaaaatatat cccgctaggt ttccaacaag aaaaatgcgg gattacctta cttcccatcc
    16321 atgaattgtt attcaaggaa cttgaagtga cacgggagat catgcgaaca ggaatgtcat
    16381 gcattcatta tcagcgcatc aaaaaagaga tgttatttat tgaattgcgc ggattttatc
    16441 agaaagagga tttggctaga ttcttcgcac caatcctggg cacggataat gatttcaagg
    16501 aaaatgtatt acaaatatat ccacaggtag aaaccgctca ggaattgatt gacaggttaa
    16561 atatgtctcc tagtgcattc aaacgaaaat tccgggagac tttcggtata tcggctcgcc
    16621 aatggctaat tcgtaaaaaa gaacaaaaat taatcaggga cattttgatg accaatatat
    16681 ccatagcaga actcgctgaa aaatacaaat ttacggccaa ctatatgacc acgttttgtc
    16741 ggaaacgttt tggcaaatca ccgacagagc tgcgcttgga acacaagaag taaacctttt
    16801 tatagcctat acactatagt actgtctctt tattatatgt agagggacaa gattttcatg
    16861 tatcttcaca tccatcacta caactcatct tatcatggtc tatttttgta gttttaagga
    16921 ctacttttgt tgccgcctat atttcaatta tatctacttt tgcggtcgaa ataaaagttc
    16981 tttataaaa
//
LOCUS       DBMDTB010000084        16917 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_1080_length_16917_cov_12.626427, whole genome shotgun
            sequence.
ACCESSION   DBMDTB010000084 DBMDTB010000000
VERSION     DBMDTB010000084.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 16917)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 16917)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16917
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1080_length_16917_cov_12.626427"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..447
                     /locus_tag="ACZPB4_12680"
     CDS             <1..447
                     /locus_tag="ACZPB4_12680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007758737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HIR1099103.1"
                     /translation="LVAKMKLIPNRAMLEGRRILFCDDSIVRGTQLRDNVKILYDYGA
                     KEVHMRIACPPLIYSCPFIGFTSSKSPLELITRQIIKELEGDENKNLDKYATTDSPEY
                     KKMVGIIAERFGLSSLKFNTLETLVEAIGLPKCKVCTHCFDGSSCF"
     gene            554..1774
                     /gene="pepT"
                     /locus_tag="ACZPB4_12685"
     CDS             554..1774
                     /gene="pepT"
                     /locus_tag="ACZPB4_12685"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0045148 - tripeptide aminopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HIR1099104.1"
                     /translation="MTVLDRFLKYVTFDTQSNEETGTTPSTPGQRVFAEALVKELEAI
                     GMEEISLDENSYVMATLPANTDEKIPTIGFIAHLDTSPDMSGKNVQPRIVTYLGGDIV
                     LDAEENVVLSQSMFPELSDYKGQDIIVTNGKTLLGADDKGGVAAIVASMQYLKDHPEI
                     KHGKIRIAFTPDEEIGQGADHFDVEKFGCDWGYTIDGGQIGELEYENFNAAGAKIIFK
                     GLNVHPGYAKDKMQNASLRAIEFASWLPAEQRPEHTTGYEGFFHLTGMTGSVEEATLS
                     YIIRDHDRKLFEEKKELLRTLVDKMNEAHPGCAHLELRDQYYNMREVVEPQKHIVDLA
                     FEAMTSVGVEPIVKPIRGGTDGARLSFMGLPCPNIFAGGLNFHGRYEFLPVRSLEKSM
                     ETVIKIIELSARKS"
     gene            1788..2873
                     /gene="gcvT"
                     /locus_tag="ACZPB4_12690"
     CDS             1788..2873
                     /gene="gcvT"
                     /locus_tag="ACZPB4_12690"
                     /EC_number="2.1.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007212859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004047 - aminomethyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0019464 - glycine decarboxylation via
                     glycine cleavage system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system aminomethyltransferase
                     GcvT"
                     /protein_id="HIR1099105.1"
                     /translation="MKTTPFTDVHIALGAKMHEFAGFNMPIEYSGIIDEHMTVVNGVG
                     VFDVSHMGEFWVKGPNALAFIQSVTSNDASVLPLGKAQYTCFPNDKGGIVDDLLVYHY
                     EPEKYLLVVNAGNIDKDWDWCVSHNTVGAELENSSDRTAQLAIQGPKAQEVLQRLTPV
                     DLSSIPYYSFVTGEFAGCKNVIISNTGYTGAGGFELYFYPSDAMTIWNAIFEAGKPEG
                     IKPIGLGARDTLRLEMGFCLYGNDLDDTTSPIEAGLGWITKFAEGKNFTNRAELERQK
                     KEGVTRKLCAFELQEKGIPRHGYEIADAEGNVIGVVTSGTMSPVLKKGIGMGYVKPEF
                     AKAGTDIFIKVRNKNLKAQVVKAPFRK"
     gene            complement(2957..3544)
                     /locus_tag="ACZPB4_12695"
     CDS             complement(2957..3544)
                     /locus_tag="ACZPB4_12695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4251 domain-containing protein"
                     /protein_id="HIR1099106.1"
                     /translation="MKRIVSFIVVLAVAMCGMTQVMAQKSITKEAKKVEREIKKQERL
                     AQDAVEGQEEFNAAVQAINNQSFVLEANNIQPMNGQVFYVNSNTNFVSLNDGQAMVQI
                     ASNSPYPGPNGLGGITVQGSASNIQTKQDDKGNVYLNMNVQGVFISATVSLMLTNGTN
                     NATVTVDPNFSGRNLRMTGTLLPYSQSNIFQGTTY"
     gene            3711..4724
                     /locus_tag="ACZPB4_12700"
     CDS             3711..4724
                     /locus_tag="ACZPB4_12700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family protein"
                     /protein_id="HIR1099107.1"
                     /translation="MDKVRFGVVGTNFISDWVIAGARQDERFELVAVYSRTQETADAF
                     ASKHNIPYTFTSLEEMAKSPLIDAVYIASPNFLHASQSILCMSYGKHVLCEKPFASNA
                     KEVRAMIEASRTYNVTLMEAMKPTLTPNFLAVRENLGRVGTVRRYFACYCQYSSRYDK
                     FKEGIVLNAFKPELSNGAMMDIGIYTVYPMVVLFGRPKKIDASGIVLSSGADGQGAVN
                     FLYEGMNATVLYSKIANSALPTEIQGEEGNLTLDRINIIRKVTYSPRLAPAMGKGPEP
                     VPEDLSVVADKDEYYYEVAEFINLVLSGKRESEINSLDNSLITLEIIDEVRRQLGIVY
                     PAD"
     gene            4879..6066
                     /locus_tag="ACZPB4_12705"
     CDS             4879..6066
                     /locus_tag="ACZPB4_12705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099108.1"
                     /translation="MYIYNSIPHITNTLNLGKDLLEVLFEKRKSLPFRYDYALDIIDE
                     NKLNILIEREVIRRNGPYIEMDEHYLSFYELLLEANEEISTSVIDENIQLVYQLIDYY
                     GKEDNDLRKLGYLRSVKAHLRKIGKILVRNVVSLQRVIDNTFKNEPSYKVKIAKLENL
                     DAKRIEINRLIVEVEKLLDRERTPFFAQVPDEELLTIARELKTELLSAGHSLIHSQQD
                     IIDYLNQIRTQVGFTRKLRRIKYLREQFELQENTNVREVVDAERSVVLEGVQPTLFKI
                     SIPYLQTDEALDVILKVADGIRPDKVIHRQELGVISAEQMENQEVGEAAINTRKMMDV
                     FSRTGGDLFSFVMGYEYNREMDFEAKVTLFCRLLSLYENELEITDRFGHTEHIEYAII
                     QRT"
     gene            6152..6721
                     /locus_tag="ACZPB4_12710"
     CDS             6152..6721
                     /locus_tag="ACZPB4_12710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="condensin complex protein MksE"
                     /protein_id="HIR1099109.1"
                     /translation="MIDNLPVQTAQIYDYLSKGNFLCSNTSVKELRTLFSVVEDNFER
                     LRDYFSHINFVLEQGNNYFYFSRKEPRATLEQKLQRFFAWIDIMDFFCTYDTAFGPGF
                     TFSPAEILVRSRIDMDLEMKLDGLKKHTGGKEKRKDILDTILDRMTKEGFIECVSDMN
                     GTWKVLSSWDYLTKMIHSINIKNEDEISQ"
     gene            6705..10334
                     /locus_tag="ACZPB4_12715"
     CDS             6705..10334
                     /locus_tag="ACZPB4_12715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HIR1099110.1"
                     /translation="MRYLNKIVFINSAAIRYSEVQLDGNIHLIGTQGVGKSTILRAIL
                     FFYNADTQRLGIPVEKKSYQDYYFPYADSSIIYEVAREDGWFTVLSYKTMNRICYRFI
                     ASPYRPDLFIDEEGAPYPSDRIRSVLDKNGIKYSGAISTYEEYRNILYGNSDNKRDYS
                     CYSLMESGSYQNIIRTIQNVLLNSRLEADYIKQTIITSLNEADSVIDLSRYRSHLSGF
                     EAQLNDIGVFREPGMARKAAGISTLSDDIRKRDLRINDLCRQLRGAYLETERILPELS
                     RKIHEQEAVKSDFYKQRDKLDAESKNRTATMEGELAVLKNSLSEAEAKRVFYAGKDIQ
                     TAMDRCNKLEILQQEQESLVVEKDLLSSKNKEASVLHANLIANLKNELAGFENEKQKQ
                     LLAAETEINARREARREYYRRLREESRHAASEEKERLLVDREKRTTEVAALKMRIKTA
                     RGQSGTSEELEAVKGRLGNYDANRKDLELKIRELKYELNYQTKEFETAGKHLDEDYQK
                     LAESNEVKIEALSAKLTELTEFLDNQKDSFFNWLSEHKPGWEQTIGQVCDERLLYGKE
                     FTAEVGEGDTFYGIRFTSGIHRNVKTKEDYLTEKKEAEEKRAGIQRFIATARQDLEAA
                     KENLRKQYQSSVKPIKEDIYHAEYELEQLAVRKKEDESRLSALRDQATRLRQEEIRRL
                     EEELNAAEAVLSSIQQEIATLQGKMDRELASLDEQEKDELAALDKELSARREAISEEI
                     VRKKAELEERKSGYDREQLDSLTASGGDPKRLEEIHSRLAYIGGEIKYINETKALIIE
                     YLKDKREMLDKVPDWTAESLRLQQIIHGEREELKKRLADVNRSIFKVDAELKELKEAN
                     RKALENREEYHRSTLLDWFTSRESIFSSMNRTDTDGDCRSLVREITIRVSEQSQKLSE
                     LRKEITAYTGNFSEDNVFAFKTSFSDDKEYMDFACDLKEFIDEDKVSEYQSRINTRNS
                     DIFRQITADTKSMVSQEGNIRGVVDQINADFKEKNFVGIIQCIEMRIDPSQNKIVNLL
                     KEIKRFNEEYSWDLGQNLFASSADDTATREKATTLLRELIKSMDAYSGNLIRLADFFD
                     LKFRVIENRNDTGFVERLTNVGSEGTDILVKSMVNIMLLNVFKRNASTVFSDFRLHCM
                     MDEIGKLHPNNVVGILKFANDRDILLINGSPTEQDALSYKHIYKLEKDGDSFTRIRRV
                     ITQFD"
     gene            complement(10452..12374)
                     /locus_tag="ACZPB4_12720"
     CDS             complement(10452..12374)
                     /locus_tag="ACZPB4_12720"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: protein motif:HMM:NF002730.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003952 - NAD+ synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA];
                     GO_process: GO:0009435 - NAD+ biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) synthase"
                     /protein_id="HIR1099111.1"
                     /translation="MNYGFVKVAAAVPHVKVADCFYNIQQIEGLMRQASQKEVQIIAF
                     PELSVTSYTCMDLFSQETLLRNAEKALLDLVNNTADLDLLTIVGCPLVSGSQLINAAV
                     AFQRGEILGVVPKSYLPSYKEFQEERWFTASSHLQQSMITIGNREVPLDCYLIFEYDE
                     VRVGIEICEDLWVPIPPSSELAMQGANLIFNLSASNELIGKHAYLRSLICQQSARCIA
                     GYVYASAGFGESSTDLVFAGNGIIAENGTLLRESERFSMEEQLVISEIDIQNLQNDRR
                     INTSFMQGYLNHNMDNGTVVSFSLPNRALDLTRVIDPHPFTPSGDALKERCEEIFHIQ
                     VAGLAKRVLHAHAQTAVVGISGGLDSTLALLVTVMTFDALKIPRDKIIGITMPGFGTT
                     DRTYTNACDLIRSLGVTLREISIKEACVQHFKDIDHDIHVHDVTYENSQARERTQLLM
                     DVANQANGLVIGTGDLSELALGWATYNGDHMSMYGVNGSIPKTLVKYLVEWVANNKVD
                     EASRTTLLDIVDTPISPELIPADEHGNIKQKTEDLVGPYELHDFFLYHFLRFGASPAK
                     IYFLAKRAFGETYDDATLKKWLHTFFRRFFQQQFKRSCLPDGPKVGSISLSPRGDWRM
                     PSDAMATLWLDEIAGL"
     gene            complement(12387..12710)
                     /locus_tag="ACZPB4_12725"
     CDS             complement(12387..12710)
                     /locus_tag="ACZPB4_12725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0090729 - toxin activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HIR1099112.1"
                     /translation="MVLKQKNPYWTAKAKEDLKEITKYYKKEVSINMAHKKVKDLKHY
                     ADLLADNPLLGFYEQALSSEPQGFRSLVHEHYKIIYFIEDDIIYISAIFDCRQNPDKL
                     RTSIR"
     gene            complement(12701..12958)
                     /locus_tag="ACZPB4_12730"
     CDS             complement(12701..12958)
                     /locus_tag="ACZPB4_12730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099113.1"
                     /translation="MTTIELQQWRESFVERYLNKIDDMEISEELERAAKKIFSKRRTP
                     RPCVIHSQEEMIAEVRKSVEDAREGRVTSSEDLDKEIETWF"
     gene            complement(13096..15282)
                     /locus_tag="ACZPB4_12735"
     CDS             complement(13096..15282)
                     /locus_tag="ACZPB4_12735"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004291175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004356 - glutamine synthetase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase III family protein"
                     /protein_id="HIR1099114.1"
                     /translation="MSKLRFRVVESAFEKKATELTTPAERPSKYYGELVFNREKMFKY
                     LPERAYERLVDSIDNGTPLDRETANAVASGMKKWAMEKGATHYTHWFHPLTEGTAEKH
                     DAFIEHDGKGGVLEEFEGKLLIQQEPDASSFPNGGIRNTFEARGYSAWDPSSPAFIVG
                     DTLCIPTIFIAYTGESLDYKAPLLKALEAVNKAAVDVCHYFNPDVKKVYAYLGWEQEY
                     FLVDEGLYAARPDLLMTGRTLMGHESSKNQQLEDHYFGAIPTRVMEFMKDLEVEALKL
                     GIPVKTRHNEVAPNQFELAPIFEECNLANDHNLLIMALMRKISRKHGFRVLLHEKPFK
                     GVNGSGKHNNWSLGTDTGILLMGPGKTPEDNLRFVTFVVNVLKAVYTHNALLKASISS
                     ATNAHRLGANEAPPAIISSFLGTQLSKVLEHLENSDTEDFNLAGKQGMKLDIARIPEL
                     LIDNTDRNRTSPFAFTGNRFEFRAVGSSANCAAAMLVLNAAVADQLRQFKAEVDAKIA
                     TGKDKFAAIIEVIRKDIKECKAIHFDGNGYSEEWKAEAARRGLDCETSVPLIFDAYLK
                     DSSVRMFESTGVMTRKELEARNEVKWEMYTKKIQIEARVLGDLTMNHIIPMATKYQSS
                     LIDNVYKMRELFPADKAAHLSSKNMEIIEDIANRTIFIKEKVDEMVNARKIANKIESE
                     REKAIAYHDRIVPMMEAIRYHIDKLELVVDDQIWTLPKYRELLFIR"
     gene            complement(15319..16548)
                     /locus_tag="ACZPB4_12740"
     CDS             complement(15319..16548)
                     /locus_tag="ACZPB4_12740"
                     /EC_number="2.6.1.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LL-diaminopimelate aminotransferase"
                     /protein_id="HIR1099115.1"
                     /translation="MALINEHFLKLQNNYLFSDIAKKVNSFKVTHPKDKIIRMGIGDV
                     TQPLAPAVIEAMHKAVEEMASKDTFHGYGPEQGYPFLIDAIIKNDYASRGVFIEPSEV
                     FISDGAKSDCGNIGDMLRHDNSIGVTDPVYPVYIDSNVMSGRTGVLENGKWSDVVYIP
                     CTEENNFVPDLPSRRVDILYLCYPNNPTGTTLTKDELKKWVNYALANDVLIMYDSAYE
                     AYIQDPNIPHSIYEIKGAKKVAIEFRSFSKTAGFTGIRCGYTVVPKELNAFTLDGQRV
                     QLNKLWNRRQCTKFNGTSYITQRGAEAVYSTAGKQQVTATINYYMTNAKIMKEGLQNC
                     GLTVYGGDNAPYLWLKTPDGLSSWKFFDKLLYEVKIVGTPGVGFGPSGEGYLRLTAFG
                     DRDDTLEAMARLRKWLR"
     gene            complement(16605..>16917)
                     /gene="dapF"
                     /locus_tag="ACZPB4_12745"
     CDS             complement(16605..>16917)
                     /gene="dapF"
                     /locus_tag="ACZPB4_12745"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008837 - diaminopimelate epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HIR1099116.1"
                     /translation="LASVGPLLECLPLFPDRTNVEFVQVLKPDEVRMRVWERGSGITQ
                     ACGTGACATAVAGVVRGKTKRKTKVIMDGGPLTIEWDERSGKVFMTGGAVNVFEGFIK
                     V"
BASE COUNT         4063 a         3823 c         4582 g         4449 t
ORIGIN      
        1 ttggtggcta agatgaaatt gataccgaac cgtgcgatgc tggaaggcag acgcatcctt
       61 ttctgcgacg actcgatcgt gcgtggtaca cagcttcgtg ataacgtgaa gatcttatat
      121 gattatgggg cgaaagaggt acatatgcgt atcgcttgcc ctccattgat ttatagttgc
      181 ccgtttatcg gttttacttc ttccaagagt cctttggagt tgataactcg tcagattatc
      241 aaggaactgg aaggggatga gaataagaat ctggataaat atgctacgac agactctccg
      301 gaatataaga agatggtcgg aattatcgcc gagcgtttcg ggttgagttc cttgaagttt
      361 aatacgctgg aaaccttggt ggaggcgatc ggcttgccta agtgtaaggt ttgtacgcac
      421 tgcttcgacg gttcaagctg cttttgatga cattttttga gagaaacagg aatagcggga
      481 caatttgtct cgctattttt ttgtcatgta acttgctttg tctactttta tggctgtttt
      541 aaaagagtga gttatgacag ttttagatag atttttaaag tacgttacgt tcgataccca
      601 gtcgaacgag gagacgggta cgactcctag tacgccggga caacgtgtct ttgccgaggc
      661 tttggtgaag gaattggaag cgattggtat ggaggagatc tccttggatg agaatagtta
      721 tgtaatggct actctgccgg ctaatacgga cgagaaaatc ccgactatcg gttttatcgc
      781 tcatttggat acgagtccgg atatgtcggg taagaatgtt caacctcgta tcgtgactta
      841 tctgggtggt gatattgtct tggatgcgga agaaaatgtt gtactatctc aatcgatgtt
      901 cccagagctt tctgattata agggacagga tattatcgta acgaatggta agactttatt
      961 aggtgccgat gataagggag gtgtagccgc tatcgtcgcc tctatgcaat atttgaagga
     1021 tcatccggag atcaagcacg gtaagatccg tatcgctttt accccggatg aggaaatcgg
     1081 acaaggtgcc gatcatttcg acgtggagaa gttcggttgt gattggggat atacgattga
     1141 cggtggacaa atcggtgagt tggaatatga gaatttcaat gccgccggcg ctaaaattat
     1201 cttcaagggc ttgaacgtac atccgggata cgccaaggat aagatgcaaa acgcttcctt
     1261 gcgtgcgatc gagtttgctt cttggttgcc ggccgagcaa cgtccggagc atacgactgg
     1321 ttatgaggga ttcttccatt tgaccggtat gaccggttcg gttgaggaag ctactctatc
     1381 ttacatcatc cgtgaccatg accggaagtt gttcgaggag aagaaagaat tgcttcgtac
     1441 gttggttgat aagatgaatg aagcgcatcc gggatgtgcg catttagagc ttcgggatca
     1501 atattacaat atgcgcgagg tcgtggagcc ccagaagcat atcgttgatt tggcgtttga
     1561 ggcgatgacc tccgttgggg tagaaccgat cgtgaaaccg atccggggag gtacggatgg
     1621 tgcccgcctg tcgtttatgg gattgccttg cccgaatatt tttgcgggag gcctgaattt
     1681 ccacggacgt tatgagttct tgcccgttcg ttcgttggag aagagtatgg aaacagttat
     1741 aaaaatcata gagctatcgg ctcgtaaatc ttaaatgcaa taattacatg aaaacaactc
     1801 cgtttaccga cgtgcatatc gccttgggcg cgaagatgca cgaattcgca ggtttcaata
     1861 tgcctatcga atattccgga attatcgacg aacacatgac tgtagtgaat ggtgtaggtg
     1921 tgtttgatgt ttcccacatg ggcgagtttt gggtaaaagg cccgaacgcc ttggctttca
     1981 ttcaaagcgt aacttctaat gacgcttctg tcttgccgct tggcaaggct caatatactt
     2041 gcttcccgaa tgacaaggga ggtatcgtgg atgacctttt ggtatatcat tacgagccgg
     2101 agaaatattt gctggtcgta aatgccggta atattgacaa ggattgggat tggtgcgtaa
     2161 gccataatac ggtaggtgcc gagttggaga attcttctga ccgtacggct caattggcta
     2221 tccaaggccc gaaggcacaa gaggttcttc aacgtcttac tccggttgac ttatcttcta
     2281 ttccttacta ttcatttgtg acgggtgagt tcgccggttg caagaacgtg attatctcca
     2341 acacggggta taccggtgcg ggtggcttcg agttgtattt ctatccgagt gatgcgatga
     2401 cgatctggaa cgctatcttc gaggctggaa agccggaagg gatcaagccg atcggtttgg
     2461 gagcacgcga tacgcttcgt cttgagatgg gcttctgctt gtatggaaat gatttggatg
     2521 atacgacttc tccgatcgag gctggtttag gctggatcac gaagttcgcc gagggtaaga
     2581 actttacgaa tcgtgcggaa ttggagcgtc agaagaaaga gggcgtaacc cgtaagttgt
     2641 gtgctttcga gttgcaggaa aagggaattc cccgtcatgg ctatgagatc gccgatgcgg
     2701 aagggaatgt aattggcgtg gttacttccg gtacgatgtc tccggtattg aagaagggga
     2761 tcggtatggg atacgtgaaa cctgagtttg cgaaagcggg tacggatatc tttatcaagg
     2821 tgcgtaataa gaacttgaag gctcaagtgg taaaggctcc tttccgtaaa taagagataa
     2881 ggctatctat aaatagttcg aaggcgatgt tcctcacgga gcaccgcctt ccttattata
     2941 gaaaagttgg acatgattaa tatgttgttc cctggaaaat gttcgattgt gagtacggaa
     3001 gtagggtacc ggtcattctc aagtttctac cggagaagtt cgggtctacg gtaacggttg
     3061 cgttgtttgt tccgttggta agcatcaagc taacggtagc ggagataaac acaccctgta
     3121 cgttcatgtt cagataaaca ttgcccttgt catcctgctt ggtctggata ttggaggcgc
     3181 taccttgtac ggtgatacca cctaatccgt taggaccggg atacggagag ttggatgcga
     3241 tctggaccat agcctgtccg tcattcaaag atacgaagtt cgtatttgaa tttacgtaga
     3301 atacctgtcc gttcatcggt tgtatgttgt tagcctccaa tacgaatgat tggttgttga
     3361 tagcttgtac agcggcgtta aactcttctt ggccttctac ggcatcttgt gccagacgct
     3421 cttgtttttt gatttctctc tctacttttt tggcttcctt tgttatcgat ttttgagcca
     3481 ttacttgtgt cattccgcac atagcgacag cgagaacgac gataaaagat acaattcttt
     3541 tcatacttga tttagtttta aaacggtttt aaattgtata gattaaacag cgtcgttgcg
     3601 aaaaagttcc tgcggcttat ccattttata gatacaataa catttccacg gagtatttat
     3661 gttaaacaga aatcgtacat ttgtaaataa agaacataat acgatagaat atggataaag
     3721 tacgttttgg tgtagtcgga accaatttca taagtgattg ggtaattgcc ggagcccggc
     3781 aggatgagcg ttttgaactg gtagctgtat attcgagaac tcaggagacg gcggatgctt
     3841 tcgcctcgaa acataatata ccgtatacgt ttacctcctt ggaggagatg gcgaaaagcc
     3901 cgttgatcga cgctgtgtat attgcctccc cgaacttcct tcatgcctcc cagagtattc
     3961 tttgcatgag ctatggcaag catgttcttt gcgagaaacc cttcgcttcc aatgcgaaag
     4021 aagtacgtgc gatgatcgag gcttcccgta catataatgt cacgttgatg gaggcgatga
     4081 agcctacgct tacgccgaac tttcttgccg tgcgagagaa tcttgggcgt gtaggtacgg
     4141 ttcgtcgtta tttcgcctgc tattgccagt attcctcccg ttatgataag ttcaaggaag
     4201 gaatcgtgtt gaacgctttc aagccggagt tgtctaatgg ggccatgatg gatatcggta
     4261 tttatacggt ctatccgatg gttgtcttgt ttggtcgccc aaagaagata gatgcctcgg
     4321 gcatagtcct gtcctcagga gcggacgggc aaggggccgt gaatttcttg tatgagggga
     4381 tgaacgccac ggtgctttat tctaagatcg ccaactccgc cttgcctacc gagatacaag
     4441 gggaggaggg gaacttgacc ttggaccgga tcaatatcat ccgtaaagtg acgtattctc
     4501 cccgtttagc tccggcgatg ggaaaaggcc cggaaccggt tccggaagac ctaagcgtgg
     4561 tcgccgataa ggatgagtac tattatgagg tagcggaatt tatcaacctc gtcttgtctg
     4621 gcaagcggga gtcagaaatc aatagccttg ataattcttt gattacattg gagattatcg
     4681 atgaagtacg ccggcagttg ggaattgtgt atccggcgga ttgataactc ttcgtgattt
     4741 tcctcttttt ccatcggggt gaaaaacttt ttccaccgtg atgaaaaagc tttttcacta
     4801 cgatggaaat cctttttcat cacggagaaa aaagggttac ttgtattttt attacctttg
     4861 tgtccttaat tgtttaggat gtacatatat aattcaatac cccatataac gaacacgcta
     4921 aatctgggaa aggacctatt ggaggtctta tttgagaaaa gaaaatcatt accgtttcgc
     4981 tatgattatg cgttggatat tatcgatgag aataaattga atatcctgat cgagcgtgag
     5041 gtgatccgca ggaacggccc ttatatcgag atggatgagc attatctctc tttctatgag
     5101 ctgcttctgg aggcgaatga ggagatttct acctcggtga tcgatgagaa tatccagttg
     5161 gtgtatcaat tgatcgatta ttatggcaag gaggataacg atttgcgtaa gctgggttat
     5221 ctgcgatcgg tcaaggcgca tttgcggaag atcgggaaga tcttggtacg taacgtggtg
     5281 tccttgcaac gggtgatcga taatacgttc aagaacgagc cgagctataa ggtgaagatc
     5341 gccaaactgg agaatctgga cgctaaacga atcgagatca accgcctgat cgtggaagtg
     5401 gagaagctgc tggatcggga acggactccc tttttcgccc aagtcccgga cgaggagctg
     5461 ttgacgatcg cccgtgagtt gaagacggag ttattgagcg ctggccatag cttgatccat
     5521 tcccaacagg atatcattga ttacttgaac cagatccgta cgcaggtggg ttttacccgt
     5581 aagctgcgtc gtatcaaata tctgcgggag cagtttgagt tacaggagaa cacgaatgta
     5641 cgggaggtgg tagatgcgga gcgttccgtg gtattggagg gcgtgcagcc taccttattc
     5701 aagatttcca ttccttattt gcaaacggac gaggcgctgg atgttatctt gaaggtggcc
     5761 gacggcatac ggccggacaa ggtgatccac cggcaggagc taggcgtgat ctccgccgag
     5821 cagatggaga atcaagaagt gggggaggcc gctatcaata cccggaagat gatggatgtt
     5881 tttagccgga ccggagggga tttgttctct ttcgtgatgg gctacgagta taaccgggag
     5941 atggatttcg aggcgaaggt tacgttattt tgccgtttac tctccctcta tgaaaatgag
     6001 ttggagataa cagaccgttt tgggcatacg gagcatatag aatatgccat tattcaaaga
     6061 acctagttgt agagacgggg cgtgtcccct gtgatgagac ggggcacgcc ccgtctctac
     6121 aactggataa aataaaacaa caataataag gatgatagat aatttaccgg tacagaccgc
     6181 acagatctat gattacctgt cgaaaggtaa ttttctgtgc tcgaatacaa gtgtaaagga
     6241 gttgaggaca ctcttctcgg tcgtagaaga taattttgag cgtttacgtg attatttctc
     6301 gcatatcaat ttcgtgttgg agcaggggaa taattacttc tacttctccc gcaaggagcc
     6361 ccgggctacc ttggaacaaa agcttcagcg tttcttcgct tggatcgata tcatggactt
     6421 cttctgtacg tatgatacgg ccttcgggcc cggtttcacc ttctcgccgg cggagatatt
     6481 ggtacgttcc cgtatcgaca tggatctaga gatgaagctg gacgggttga aaaaacatac
     6541 cggaggcaag gagaaacgca aggatatcct cgataccatc ttggacagga tgacgaaaga
     6601 gggctttatc gagtgcgtaa gcgatatgaa cgggacgtgg aaagtgctct cctcgtggga
     6661 ctacctcacg aagatgatcc atagtattaa cataaagaac gaagatgaga tatctcaata
     6721 aaatagtatt tataaacagc gccgctatcc gttactcgga agtacagctg gatggaaata
     6781 tacatttaat cggaacgcag ggagtgggga agagtacgat cctccgtgcg atccttttct
     6841 tttacaacgc cgatacgcag cggctcggaa tcccggtcga gaagaagtcg tatcaggatt
     6901 attatttccc ttatgccgat tcctcgatca tctacgaggt agcgagggag gatggttggt
     6961 ttacggtact tagttataag acgatgaacc gtatctgcta ccgttttatc gcctctccgt
     7021 accggccgga tctttttatc gacgaggagg gagcgcctta tccgtcggat cgtatccgct
     7081 cggtgctcga taagaacggt atcaaatata gcggggcgat ctccacgtat gaggaatacc
     7141 ggaatatcct ctacggaaac tcggataata aacgggatta ctcctgttat tccttgatgg
     7201 agagcggctc gtatcagaat atcatccgta cgatccagaa cgtcttgctg aactcacgct
     7261 tggaggcgga ttatatcaag cagacgatca tcacctcctt gaacgaggcg gatagcgtga
     7321 tcgatttgag ccgttaccgg agccatctat ccggttttga ggcgcaactg aatgatatcg
     7381 gtgttttccg tgagccgggc atggcgcgga aggccgccgg gatctccacc ttgtcggacg
     7441 atatccgtaa gcgggattta cggatcaacg atctgtgtcg ccaattacgc ggggcttatc
     7501 tggaaacgga gcgtatcttg ccggagttgt cccggaagat acacgagcag gaggcggtca
     7561 aatcggattt ctataagcaa agggataagc tagacgctga atcgaagaac cggacagcca
     7621 cgatggaagg cgagttggcc gtgctgaaaa actccttgtc agaggcggaa gcgaaacggg
     7681 ttttctatgc cgggaaagat atccagacgg cgatggatcg ttgtaacaaa ttggagatct
     7741 tacagcagga acaggaatcc ttagtcgtgg agaaagattt gctttcttcc aagaataaag
     7801 aagcctcggt cttgcacgcc aatttgatcg ctaatctgaa gaacgagttg gccggcttcg
     7861 agaacgagaa acagaaacaa ttactggcgg cagagaccga gatcaatgct cgtcgggagg
     7921 ctcgccggga gtattatcga cggctacggg aggaatcgcg ccatgccgcc tcggaggaga
     7981 aagagcgttt gttggtggat cgggagaaac gtacgacgga ggtcgccgcc ttgaagatgc
     8041 gtatcaagac tgcccggggg cagtcgggaa cctcggagga attggaggcg gtcaaggggc
     8101 gtctcggcaa ttacgatgcg aaccggaagg acttggagct gaagatccgt gagctgaagt
     8161 acgagttgaa ctaccagacg aaagagttcg agaccgccgg gaagcatctg gatgaggatt
     8221 atcaaaagct agcggaatcc aacgaggtga agatcgaggc cctgagcgct aagctaacgg
     8281 aactgacgga gttcttggat aaccagaaag atagcttctt caactggctg tccgagcata
     8341 agcccggctg ggagcagacg atcgggcaag tgtgtgacga gcgtctgctt tacgggaaag
     8401 agtttacggc ggaggtaggc gagggagata ccttttatgg aatccgcttc acctccggga
     8461 ttcaccggaa tgtcaagacc aaggaggatt acttgacgga gaagaaggag gccgaggaaa
     8521 aacgtgccgg aatccagcgg ttcatcgcta cggcgcggca ggatttggag gcggctaaag
     8581 agaatcttcg caagcaatat caatcctccg tgaagcccat caaggaggat atctatcatg
     8641 cggaatatga gttggagcaa ctggcggtcc gcaagaaaga ggacgagtct cgtctgtcgg
     8701 ccttgcggga tcaggcgacc cgtctgaggc aggaggagat ccggcgcttg gaggaggagt
     8761 tgaacgctgc cgaggccgtc ctttcctcga tccagcagga gatcgccacg cttcaaggca
     8821 agatggaccg ggaactcgct tccttggatg agcaagagaa agatgagttg gctgctttgg
     8881 ataaggaact ctccgcccgg agggaagcta tctcggagga gatcgtacgc aagaaagcgg
     8941 agttggaaga gcgcaaatcc ggatatgaca gggagcaatt ggatagcttg accgctagcg
     9001 gtggcgatcc gaaacgtttg gaggagatcc attcccgctt ggcgtatatc ggtggggaga
     9061 ttaaatatat caacgagacc aaggcattga ttatcgagta tctgaaagat aaacgagaga
     9121 tgctggataa ggtacccgac tggacggcgg agagcctgcg cttgcagcag atcatccacg
     9181 gggaacggga ggaattgaaa aaacgtctgg cggacgtgaa ccggagtatc ttcaaggtag
     9241 atgccgagtt gaaggagctg aaggaggcca accggaaagc gttggagaac cgggaggaat
     9301 atcaccgctc taccctgttg gactggttta cctctaggga atccatcttc tcttccatga
     9361 accgtaccga tacggatggc gattgccgtt ccttggtacg ggagatcacg atccgcgtca
     9421 gcgagcaatc ccagaagctt tccgagctgc gcaaggagat aaccgcctac accggcaatt
     9481 tctccgagga taatgtgttc gccttcaaga cgagcttctc ggatgataaa gagtatatgg
     9541 atttcgcttg cgacttgaag gagtttatcg acgaggataa ggtctcggaa taccaatcgc
     9601 gtatcaatac ccgcaactcc gatatcttcc ggcagattac ggcggacacg aaaagcatgg
     9661 tctctcagga aggcaatatc cgtggcgtgg tggatcagat caacgccgat ttcaaggaga
     9721 agaacttcgt ggggattatc cagtgtatcg agatgcgtat tgatccgagc cagaacaaga
     9781 tcgtcaatct gttgaaggag atcaagcgat tcaacgagga atatagctgg gatttggggc
     9841 agaacctctt cgcttcctca gccgacgata cggctacccg ggagaaggcg acgacgttgc
     9901 tacgtgagtt gatcaagtcg atggacgctt attccggcaa cttgatccgc ttggcggact
     9961 tcttcgacct taaattccgg gtgatcgaga accggaatga tacgggcttc gtagaacgtc
    10021 ttacgaacgt aggctccgag ggtacggata tcttggtcaa atccatggtg aatatcatgt
    10081 tgctgaacgt gttcaagcgg aacgcctcca cggtattctc cgatttcagg ctccattgca
    10141 tgatggatga gatcgggaag ctgcacccga ataacgtggt ggggatcttg aaatttgcca
    10201 acgaccggga tattctcttg atcaatggct caccgaccga gcaggatgcc ctgtcctata
    10261 agcacatcta taaactggag aaggacggcg atagcttcac ccggatccgg agggtgatca
    10321 cgcagttcga ttaggcagga tcatagccga ggctttctca ccgatcataa ctgaggctct
    10381 ctcacgggtc atagccgagg cttcgacacc catgagagag cctcgtctat gaccataccc
    10441 gtgaacgaat gttaaagccc tgcgatctca tccagccaaa gcgtagccat cgcgtcgctc
    10501 ggcattcgcc agtctccacg cggggagagg ctgatggagc ctactttcgg gccgtcgggc
    10561 aggcaactgc gcttgaactg ttgctggaag aagcggcgga agaaggtatg gagccatttc
    10621 ttgagggtgg catcgtcgta ggtttccccg aatgcccgct tcgccaagaa gtagatcttc
    10681 gcgggggagg caccgaagcg caggaagtga tagaggaaga aatcgtgcag ctcgtagggg
    10741 cctaccaaat cctccgtctt ctgcttgata tttccatgct cgtcggcggg aatcaattcc
    10801 gggctgatcg gagtgtctac tatatctaat aacgtggtgc gggaagcctc gtctaccttg
    10861 ttgttggcaa cccattccac cagatatttg accaatgtct tgggaatgct accgttgacg
    10921 ccgtacatag acatatggtc gccattgtaa gtagcccagc ccaaggcaag ctccgagaga
    10981 tcccccgtac cgatcacgag gccgttcgct tggttcgcca cgtccataag aagttgggta
    11041 cgctcgcggg cttggctgtt ctcgtaggtc acgtcatgta catggatgtc gtgatcaata
    11101 tccttgaaat gttggacgca agcctccttg atggagatct cccggagggt cacgcccagg
    11161 gagcgtatca agtcgcaggc attggtatag gtacgatccg tcgtcccgaa gccgggcatg
    11221 gtgatgccga tgatcttatc ccgtgggatc ttcaaggcgt cgaaggtcat gacggtgacc
    11281 agtagggcca aggtggaatc cagtcccccg gagatgccta cgacggcggt ttgggcgtgg
    11341 gcatggagga cacgcttggc gagtcccgct acctgtatat ggaatatttc ctcgcaacgt
    11401 tctttcaagg catcgccgga aggggtaaag ggatgcgggt cgattacccg ggtcaagtcc
    11461 agcgcccggt tgggaaggct gaatgagact acggtgccgt tatccatgtt atggttgaga
    11521 taaccctgca tgaaactggt gttgatccgt cggtcgttct gtaagttctg gatatcgatc
    11581 tcgctgataa cgagttgctc ctccatggag aaacgctcgg attcccttaa caacgtgccg
    11641 ttctctgcta tgataccgtt tcccgcgaat acgaggtcgg tactggattc cccgaaaccg
    11701 gcggatgcgt agacgtatcc ggcgatacaa cgtgcggatt gctggcagat caaggatcgt
    11761 aagtaagcat gcttaccgat caactcgttg ctggcggata gattgaatat caagttcgcc
    11821 ccctgcatgg ctagctcgga gctgggaggg atgggaaccc aaagatcctc gcagatctcg
    11881 atacccacgc gtacctcatc atactcgaag atcaggtagc aatccagcgg cacttcccgg
    11941 ttaccgatcg tgatcatgga ttgctgtagg tgtgaagagg ccgtgaacca acgctcttct
    12001 tggaactctt tgtagctggg caggtagctc ttgggcacta cccctagtat ctcgccccgt
    12061 tggaaagcga cggcggcgtt tatcagttgg cttccgctga caagcgggca acctacgatc
    12121 gttagtaaat ccagatcggc ggtgttgttc actaaatcca gcaaggcttt ctcggcgttt
    12181 ctgagtaagg tctcttgcga gaacaaatcc atgcaagtat aagacgtaac cgataattcg
    12241 gggaaggcga tgatctggac ctctttttgg gacgcttggc gcatcaatcc ctcgatctgt
    12301 tgaatattat aaaagcagtc agccacttta acatgtggta cggctgccgc tactttgacg
    12361 aatccgtaat tcatatttgt tattgtttat ctgatagatg ttcttaattt atcggggttt
    12421 tgacgacagt cgaatattgc ggagatatag atgatatcat cttctataaa atagatgatt
    12481 ttgtaatgct catgaacaag agaccgaaag ccttgcggct ccgaggataa ggcttgctca
    12541 taaaaaccga gaagaggatt atccgctaac aaatctgcgt aatgtttcag atccttgact
    12601 ttcttgtggg ccatgttgat agaaacctcc ttcttataat acttcgtaat ttctttcaaa
    12661 tcttctttgg ccttggctgt ccaatatgga tttttctgtt tcagaaccat gtctctatct
    12721 ctttatctag atcctcactt gatgtgactc taccttctcg ggcgtcttct accgatttcc
    12781 gtacctctgc tatcatctcc tcttgcgagt ggattacgca agggcggggt gtccttctct
    12841 tggaaaagat ctttttggca gcccgttcca gttcctccga tatctccatg tcatcgatct
    12901 tgttaaggta tctctccacg aagctttctc tccattgctg taactctatt gtcgtcatat
    12961 caatttccct cctatatatt tatgccccaa aggtatgtat tttgtatggg ataaaaaaga
    13021 aggagaggta tacttcgcag catcctctcc ttattaacac aaaacaatca acaaaaaact
    13081 actgtctgaa taagactatc tgatgaataa aagctcacgg tatttcggca aggtccatat
    13141 ctggtcgtcg acaaccagtt ccaacttgtc gatatggtaa cggatggctt ccatcatcgg
    13201 gacgatccgg tcgtggtaag cgatcgcctt ctcccgctcg ctctcgatct tgttggctat
    13261 cttgcgggcg ttgaccatct cgtccacttt ttccttgatg aagatcgtgc ggttcgctat
    13321 atcctcgatg atctccatgt tcttggagga tagatgggcg gctttatcgg cggggaataa
    13381 ttcacgcatc ttatatacgt tgtcgatcaa ggaagactgg tatttggtgg ccatcgggat
    13441 gatatggttc attgtcaggt cgcctaatac acgggcctcg atctggatct tcttcgtgta
    13501 catctcccat ttgacctcgt tgcgagcctc cagctccttg cgggtcatga ctcccgtgga
    13561 ctcgaacatg cggacgctgc tatctttcaa ataagcgtcg aagatcaaag gcacgctggt
    13621 ctcgcaatcc aagccccggc gtgcggcctc ggccttccat tcctcgctgt agccattgcc
    13681 gtcgaaatgg atcgccttgc attccttgat atccttgcgg attacctcga tgatagcggc
    13741 gaacttatcc tttccggtgg ctatcttagc gtctacctcg gccttgaact gcctcaactg
    13801 atccgctacg gcggcgttca ataccagcat ggcggcggcg cagttcgcgg aggaacctac
    13861 ggcacggaac tcgaaacgat taccggtgaa ggcgaaaggg gaggtacggt tacgatccgt
    13921 gttatcgatc aataactcgg ggatacgggc gatatcgagt ttcatgcctt gctttcccgc
    13981 taggttgaaa tcttccgtat cgctgttctc cagatgttcc aataccttgg ataactgtgt
    14041 acctaagaag ctggatatga tcgcaggggg agcctcgttc gctcccagac gatgggcgtt
    14101 ggtcgcgctg gagatgctgg ccttcagcaa tgcgttatgg gtgtacacgg ctttcagtac
    14161 gttgaccacg aaggtcacga agcgcaggtt gtcttccggc gtcttacccg gtcccatcaa
    14221 aaggattccg gtatcggttc ccagcgacca gttattgtgc ttgccggaac cgttcacgcc
    14281 tttgaacggt ttctcgtgca acaggacacg gaacccatgt ttgcgggaga tcttgcgcat
    14341 tagggccatg atcagtaggt tatggtcatt ggcgaggttg cattcctcga agatgggagc
    14401 cagctcgaat tggttcgggg cgacctcgtt atgacgggtc tttacgggaa tgccaagttt
    14461 caatgcctca acctcgaggt ctttcatgaa ttccatgaca cgggtgggga tggctccgaa
    14521 gtaatgatcc tccaactgtt ggttcttcga gctctcgtgc cccatcagag tacggccggt
    14581 catcaacaga tcgggacgtg cggcgtatag gccctcgtct actaggaagt attcctgttc
    14641 ccaacctagg taggcgtata ctttcttcac gtccgggttg aagtagtggc agacatcgac
    14701 cgccgccttg ttcacggctt ccaaggcttt cagcaaggga gctttgtagt cgagggactc
    14761 gcctgtgtaa gcgatgaaga tcgtcgggat gcacagggtg tctcctacga taaaagcagg
    14821 ggaggaagga tcccaagccg agtagccacg ggcctcgaac gtattgcgga taccgccgtt
    14881 cgggaaactg gaggcatccg gctcttgctg gatcagtagt ttgccctcga attcctcaag
    14941 tacgccgcct ttgccatcgt gctcgatgaa agcatcgtgc ttctcggcgg taccttccgt
    15001 caagggatgg aaccagtggg tgtagtgggt agcgcctttt tccatcgccc atttcttcat
    15061 gccggaggcc acggcgttcg ctgtctcacg gtctaacggg gtaccgttgt cgatggagtc
    15121 caccagtctc tcgtacgctc tctctggaag atatttgaac atcttctcac ggttgaatac
    15181 cagctcgccg taatacttgg aaggtctctc ggcgggagtg gttagctcgg tcgctttttt
    15241 ctcgaacgcc gattctacga ctctaaatct taactttgac ataatacctg atgattattg
    15301 ttgtttatag taaatgactt atcttagcca cttcctcagc ctagccatgg cctctagggt
    15361 gtcatcccta tcgccgaaag cggtgaggcg tagataacct tccccgctcg gtccgaatcc
    15421 cactccgggg gttccgacta tcttgacttc ataaagcagt ttgtcaaaga atttccatga
    15481 ggagaggccg tccggggtct ttagccagag gtatggggcg ttatcgcctc cgtacaccgt
    15541 gagaccgcag ttttgcaggc cctctttcat gatcttcgcg ttggtcatat aataattgat
    15601 agtagctgtc acttgctgtt tcccggcggt ggaataaacc gcttccgcac cccgttgggt
    15661 tatgtaactg gttccgttga atttcgtgca ttggcgacgg ttccataatt tgttcaactg
    15721 tacccgttgc ccgtccagcg tgaaggcgtt cagctccttc ggtacgaccg tgtatccgca
    15781 acgtatcccc gtgaacccgg cggttttaga gaagctccgg aattcgatag ctaccttctt
    15841 cgctcctttg atctcgtaga tagagtgggg gatattcggg tcctgtatat aagcttcgta
    15901 agcggagtcg tacatgataa gcacgtcgtt ggcaagggca tagtttaccc atttcttcaa
    15961 ttcgtcctta gtcaaggtcg ttccggtcgg gttattggga tagcagaggt aaaggatgtc
    16021 caccctgcga ctgggcagat ccggtacgaa gttgttttcc tccgtgcaag ggatgtatac
    16081 gacatcgctc catttcccgt tttccaatac cccggtacgt ccgctcatta cgttcgagtc
    16141 gatgtagacc ggatatacgg ggtctgtcac cccgatacta ttgtcgtggc ggagcatgtc
    16201 gcctatattt ccacaatcgc ttttcgctcc gtcgctgatg aatacctcgc tcggttcgat
    16261 aaagactccc cggctggcat aatcgttttt aatgatagcg tcgattagga aaggatatcc
    16321 ctgctcgggg ccatatccgt ggaatgtatc cttgctcgcc atttcttcca cggctttatg
    16381 catcgcctca ataacggcgg gggcaagtgg ttgcgtaaca tcaccaatac ccattcgaat
    16441 gatcttatct ttgggatggg taaccttgaa gctgtttacc tttttcgcga tgtcggagaa
    16501 aaggtaattg ttctgtagtt tcaggaaatg ttcattaatt agtgccatac tcagttcttt
    16561 tgtttttatg ttgttgtttt tgttgttttg tcttgttccc cgtgtcagac tttgatgaat
    16621 ccctcgaaca cgttgaccgc tccgccggtc ataaagacct taccgcttcg ctcgtcccac
    16681 tcgatggtta aagggccccc atccatgatg accttcgtct ttcgctttgt cttcccacgt
    16741 acgaccccgg ccacggcggt ggcgcaagct ccggttccgc aggcttgggt gatgccggaa
    16801 cctcgttccc acaccctcat ccgtacctcg tccggcttta gcacctgcac gaactccacg
    16861 tttgtccggt ccggaaaaag cgggaggcat tccagtaacg ggcctacgct tgccaga
//
LOCUS       DBMDTB010000085        16755 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_1092_length_16755_cov_10.914855, whole genome shotgun
            sequence.
ACCESSION   DBMDTB010000085 DBMDTB010000000
VERSION     DBMDTB010000085.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 16755)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 16755)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16755
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1092_length_16755_cov_10.914855"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..339
                     /locus_tag="ACZPB4_12750"
     CDS             <1..339
                     /locus_tag="ACZPB4_12750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099117.1"
                     /translation="RLTEIMDRERANRNSIHLYCTGPYWVAFERSAYQLHRAFPDSET
                     TPLRLFAYPFPIVMVSVTDRSLRSYARKHILRRDGSDYKLLTVPGFPLADYREWHAGE
                     VEGLPRLSEN"
     gene            513..941
                     /locus_tag="ACZPB4_12755"
     CDS             513..941
                     /locus_tag="ACZPB4_12755"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BT0820 family HAD-type phosphatase"
                     /protein_id="HIR1099118.1"
                     /translation="MIIAVDFDGTIVEHKYPAIGRELPFAIETLRKLQSDRHKLILWT
                     VREGGLLEEALSFCRERGLEFYAVNRDYPEEERDRNNHFSRKLKADVFIDDRNLGGLP
                     DWGTIYEMVTKGLSYEDLTRKYESEYEPEKPKGFLSRLFR"
     gene            989..1786
                     /locus_tag="ACZPB4_12760"
     CDS             989..1786
                     /locus_tag="ACZPB4_12760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015159 - polysaccharide transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0015774 - polysaccharide transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis/export family
                     protein"
                     /protein_id="HIR1099119.1"
                     /translation="MKIKRLLFLFSLPLLLAACTSYKNVPYLQNPEAVNDLEGTLPLY
                     DAKIMPKDLLSITVNTTDPQAAAPFNLTVQTPLNAALTNINTTTQPTLQQYLVNNSGE
                     IDFPVIGTLRVGGLTKNEAESLIRERLRPYLKEAPIVTVRMANYKISVLGEVARPGSF
                     TIGNEKVNVLEALAMAGDMTIYGVRDNVKLIREDESGKRKIINLDLNNAGIVTSPYYY
                     LKQNDILYVTPNETKARNSDIGNSTTLWVSSISILVSIAGLLVNILK"
     gene            1824..>2362
                     /locus_tag="ACZPB4_12765"
     CDS             1824..>2362
                     /locus_tag="ACZPB4_12765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Wzz/FepE/Etk N-terminal domain-containing
                     protein"
                     /protein_id="HIR1099120.1"
                     /translation="MVDDGINTSNNNNNNNNPEGEDREINLYAVFFKYMVYWPWFVAS
                     VLACCIGMYVFLRYQTPVYNVTSSVLIKEDEKKGANAASGLAAIQDLGMLSMTSNFDN
                     EVEILRSRTLIKKVVNDMGLYIDMEESNALGFNPPLYKNSPVNVFITPEEADRLVAPV
                     ELRMRYTKEGQLTVRAEYK"
     assembly_gap    2363..2462
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <2463..3972
                     /locus_tag="ACZPB4_12770"
     CDS             <2463..3972
                     /locus_tag="ACZPB4_12770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013616311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="polysaccharide biosynthesis tyrosine autokinase"
                     /protein_id="HIR1099121.1"
                     /translation="FKQRSGLTNLTSDAQMALQESSRYEQQRTENATQINLVQYLRNY
                     IDDPANMDEVIPANVGLRDQNLTSVIDQYNTMIIERKRLLRTSSDSNPAIINMNAGIE
                     AMRRNVKTTVNSVLKGLQIAKADIDRQASKFESRISDAPRQEKEFMTISRQQEIKATL
                     YIMLLQKREENAITLAATANNGRIIEEPLADERPVAPKRMVFMLAALILGLAIPVGIV
                     YLHDLLKYKIENREDVEAITGVAILAELPLVKKTGEGSIVVRENKNDLMEEMFRGLRT
                     NLLFMLGKDERVILFSSTQPGEGKSFVAGNLAVSLAYLGKRVVVVGMDIRKPGLNKVF
                     NISRKMEGITNYLSDPDHVELFDMVQRSDISPNLDILPGGPIPPNPTELVARDVLEKA
                     IARLKERYDYVILDTAPIGMVTDTAIIGRVADMCVYVCRADVTPKAGFSYINVLRRER
                     KFPKLATVINGLDMTKRKNSYGYGYGKKYGYGKGYGYGYGYGYGFEAGDKKK"
     gene            3987..5126
                     /locus_tag="ACZPB4_12775"
     CDS             3987..5126
                     /locus_tag="ACZPB4_12775"
                     /EC_number="2.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MraY family glycosyltransferase"
                     /protein_id="HIR1099122.1"
                     /translation="MQITLLLLSGFLFSVLFGMVIIPRILVISHKKRLYDVPDSRKVH
                     TTPVPRLGGLSFFPVILMSMFLVIGFRLYFWDMGSSSLSFNMLYEYLFLFVGMTLLYL
                     VGVCDDLVGVGYRYKFAVQIVSALLLVLSGNWFGSLGGLFGVYSVPAWVGIPVTVFIV
                     VYITNAINLIDGIDGLASGLCSIALSVLSVIFFIRMQYVYALLAICTLGVLMPFWCYN
                     VFGNANRGHKLFMGDAGSLTLGYVISFLIIHLCVSNQVLPELPNPYMVIAFSTVLVPL
                     LDVIRVVLHRLRNHRNPFLPDKNHFHHKLLRTGMRVRMVMVTILCVSVFFIVLNVLLA
                     MKVNATYLLLLNLVLWSILHLTINRFITRHHKEQELKEIGGIFTK"
     gene            complement(5176..5622)
                     /locus_tag="ACZPB4_12780"
     CDS             complement(5176..5622)
                     /locus_tag="ACZPB4_12780"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_process: GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HIR1099123.1"
                     /translation="MGKVYCFYQNYREVSLLVIHCSATRYDRDFPVEALRSSHKARGF
                     ADIGYHFYITRDGELHRCRPVNQIGAHAAGWNDKSIGICYEGGLDEQGRPADTRTYAQ
                     RCTLMDLLRQLRRDYPEARILGHYQLSPYIRKACPCFDAREEYLVL"
     gene            complement(5641..5736)
                     /locus_tag="ACZPB4_12785"
     CDS             complement(5641..5736)
                     /locus_tag="ACZPB4_12785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="smalltalk protein"
                     /protein_id="HIR1099124.1"
                     /translation="MKKSVWSTIIKVIIAVATAIAGALGIQSCIL"
     gene            5763..5885
                     /locus_tag="ACZPB4_12790"
     CDS             5763..5885
                     /locus_tag="ACZPB4_12790"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099125.1"
                     /translation="MNYELGIPADIRGKLGFPLDGLSGRASSEETVASVRSIPV"
     gene            complement(5989..6456)
                     /locus_tag="ACZPB4_12795"
     CDS             complement(5989..6456)
                     /locus_tag="ACZPB4_12795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HIR1099126.1"
                     /translation="MPQAFQARKFFIPKTDPKQEVYKPVPYYFGTLSTQDAADQIAEE
                     SSLTKGDVLNVLDRYQRYVIKNLQKGYKVELLGFGTVYNRFVTEKGVATAPEVKATHI
                     RTIVPGFSPSYTILNGARRYSLLGEKTSLLKVTILGTPVEEGGGSDSESPDEI"
     gene            complement(6762..6968)
                     /locus_tag="ACZPB4_12800"
     CDS             complement(6762..6968)
                     /locus_tag="ACZPB4_12800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4248 domain-containing protein"
                     /protein_id="HIR1099127.1"
                     /translation="MFLPLRKSALAASYFPELASHQACNRLRRWIIRCTELHDKLLET
                     GYRPEQRIFTPRQIRLIIHYLGEP"
     gene            complement(7087..8892)
                     /locus_tag="ACZPB4_12805"
     CDS             complement(7087..8892)
                     /locus_tag="ACZPB4_12805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3987 domain-containing protein"
                     /protein_id="HIR1099128.1"
                     /translation="MNPLSDLERLVAAIEKQGANIAPTYQEYMPIAFAIANDCGEAGR
                     TFFHRICRMSEKYVSTEADKLYDHALKGGNGRNGLGSVFHLADLAGVKLDKSMAEAGK
                     LSNFQTFTPPSHTHTCTHEEQSVKNVPPAFPEYPWPAFLKRMIDRGDTPAQKDILLLG
                     GITVLGATLNKSIRISYGRKFYYPCLQTFIVAPPASGKGALAWTRRLAEPIHEAMMAN
                     YRQRHKAYREEKSRWDSLGKKKSDTPEPEMPPLKMFLIAGNNSGTGVLENLIEADGIG
                     LICETEADTVSTAIGTEHGHWSDTLRKCHDHERLAFNRRTNREYRECPASYLSVLLSG
                     TPAQVRPLIPSAENGLFSRQLFYRMPPIDEWADQFEQGDEDMDSLFSDWGKQWKMLVD
                     YLRERVNIIQFHLSDTQKERFNSCFARIFGHAGLSYGYPMRSSVARIAINICRIASVV
                     AFLRSVESLLIPQAILDSQFSILNCPGLSPALEIPEENVRDGIVPSLELRINDDDFKA
                     VLSLVEPLYRHSAGILSLLPSDEVPRSRTPTPQEALFAALPLSFNRQQALEEAERNNI
                     PTATLDTCLKRMQERGTLEKNGRGEYSFGGRVTHK"
     gene            complement(8954..9523)
                     /locus_tag="ACZPB4_12810"
     CDS             complement(8954..9523)
                     /locus_tag="ACZPB4_12810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BT4734/BF3469 family protein"
                     /protein_id="HIR1099129.1"
                     /translation="MKESIFSFFNAPITNQVPNGVVCVSQLYAYITTSEWLRERTDQV
                     RAASSDEKRFRRLKQSLLPYVTPAGIFSYRKEDHLLVPSGEFVIDIDHLSSPEEAICW
                     RDTLFADERLRPDLSFVSPSTTGIKLLVPYRLSIKKTVEESFDEAVRFAWEYLEWKYG
                     LKADATNADLSRACFLCHDPSARLGDRNC"
     gene            complement(9552..9689)
                     /locus_tag="ACZPB4_12815"
     CDS             complement(9552..9689)
                     /locus_tag="ACZPB4_12815"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099130.1"
                     /translation="MLTIITLFTGDIYFYPHFIHHTSVSVPVPSIAIPGTGRNAFLYR
                     Q"
     gene            9707..10198
                     /locus_tag="ACZPB4_12820"
     CDS             9707..10198
                     /locus_tag="ACZPB4_12820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099131.1"
                     /translation="MTENQERAEQARSAFTVNGGNVQILPNATIAIQNIHWGDGTVTR
                     TERWITPAESGLHESPSPPINSPAPPVTAEPSSLALFIPDEATRLVYEARLCACPDTV
                     TLCQTVLTDLYNEILADYSSPLKLVKSRAFISALLPHLTFVNGANVPSIRYGIRKYVL
                     GEG"
     gene            10236..11141
                     /gene="rfbA"
                     /locus_tag="ACZPB4_12825"
     CDS             10236..11141
                     /gene="rfbA"
                     /locus_tag="ACZPB4_12825"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HIR1099132.1"
                     /translation="MKGIVLAGGSGTRLYPITKGVSKQLLPIFDKPMVYYPISVLMLA
                     GIREILIISTPYDLPGFKRLLGDGSDYGVCFEYAEQPSPNGLAQAFTIGAEFIGDDSV
                     CLVLGDNIFHGNGFTSMLKEAVRTAEKENRATVFGYWVSDPERYGVAEFDQAGNCLSI
                     EEKPECPKSNYAVVGLYFYPNKVVDVASSIQPSARGEYEITTVNQRFLEDGELRVQTL
                     GRGFAWLDTGTHDSLSEASTYIEVLEKRQGLKVACLEGIAYRQGWITEERMRELAQPM
                     LKNQYGQYLLKVIEELKETGDPNLG"
     gene            11143..11724
                     /gene="rfbC"
                     /locus_tag="ACZPB4_12830"
     CDS             11143..11724
                     /gene="rfbC"
                     /locus_tag="ACZPB4_12830"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008830 - dTDP-4-dehydrorhamnose
                     3,5-epimerase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HIR1099133.1"
                     /translation="MEVIKTDIEGVVIIEPKVFDDARGYFFESFSQREFEEKVRKINF
                     VQDNESMSSYGVMRGLHFQKPPFTQSKLVRCVKGCVLDVAVDIRKGSPTYGKHVAVEL
                     SEENHRQFFVPRGFAHGFAVLSEIAVFQYKCDNFYAPQADGGIRIKDESLGIDWRIPM
                     DKVLLSEKDIKHPCLEDFDSPFDYHVNLYPEFE"
     gene            11726..12634
                     /gene="rfbD"
                     /locus_tag="ACZPB4_12835"
     CDS             11726..12634
                     /gene="rfbD"
                     /locus_tag="ACZPB4_12835"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008831 - dTDP-4-dehydrorhamnose reductase
                     activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HIR1099134.1"
                     /translation="MNILVTGANGQLGNEMRIIARESDDHYVFTDVNQVEGVETGFLD
                     ITDLEAVRKMVAAQRVDVIVNCAAYTNVDMAESNEELVEKLNAEAPENLAKVMKETNG
                     FLVQISTDYVFGKEPCNVPCQEDQQGTPTGVYGMSKLHGEQKIQAIGCKHVIIRTAWL
                     YSEFGKNFCKTMMNLTATKPHLKVVFDQVGTPTYALDLAKAIETVLKDYADKKNEHDY
                     DKTGIYHYSNEGVCSWFDFTKSIAEYNGTTACDVQPCHSDEFPSPVKRPFYSVLDKSK
                     IKETFGIRIPYWTESLRQCIANIKNK"
     gene            12643..13767
                     /locus_tag="ACZPB4_12840"
     CDS             12643..13767
                     /locus_tag="ACZPB4_12840"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HIR1099135.1"
                     /translation="MSKRNIVITGGAGFIGSHVVRLLVNKYPEYNIFNLDKLTYAGNL
                     ANLKDVEDKPNYRFIRMDICDFKAFYQLMQDKQIDGIIHLAAESHVDRSIKDPFTFAQ
                     TNVMGTLALLQAAKLYWESLPERYEGKRFYHISTDEVYGALTMNYPEGIEPPFTTTAS
                     SSEHHLAYGDDFFYETTKYNPHSPYSASKASSDHFVRAYHDTYGMPTIVTNCSNNYGP
                     YQFPEKLIPLFINNICHRKPLPVYGKGENVRDWLFVEDHARAIDTIFHHGKIAETYNI
                     GGFNEWKNIDIIKVLINTVDRLLGRKEGEDLDLITYVTDRLGHDARYAIDSTKLQKEL
                     GWEPSLQFEEGIEKTVRWYLDNQEWMDNITSGEYQRFNNL"
     gene            13840..15378
                     /locus_tag="ACZPB4_12845"
     CDS             13840..15378
                     /locus_tag="ACZPB4_12845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0140327 - flippase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HIR1099136.1"
                     /translation="MSTENVINNQRIAKNTFLLYLRTIFVLAVSLYTSRLVLKVLGVD
                     DYGIYQVVGGMVTMFGILSNALSAAISRFITFELGSGKAERLKRLFSTSVVVQYVLAG
                     IVFIIAEVVAIWFMETEMQLPKGREFAAKCVLHCSLFTFCVNLISIPYNACIIAHEHM
                     KAFAYMSVVDVVLKLIACLGVMCIPIDKLISYSIFLAVISISIRILYWLYCKKHFEET
                     RGSVAFDWCIFKEMLGFSGWSFLTNANGILNTQGVNMLINVFFGVTVNASRGISSQVE
                     SAVLQFVNNFTMAVNPQIIKSYAAGDIQGLYTLICRGAKFAYFAMFIMVLPLVCETPY
                     MLSVWLTIVPPHTVIFVQLSLILGIFDCIGFSSYTACMATGRIRLYSITLAIIGALEF
                     PLTWIFFTYGAPVVSTYYLYIFVKILVLIARVILLRDMVGLPPQMYIIEVLIPILLTT
                     LIAIIPSLLIISFFPSSFVRLCISVIVAIISVGLSALYIGMTQREREVILEKVNSVVN
                     RLKK"
     gene            15375..16190
                     /locus_tag="ACZPB4_12850"
     CDS             15375..16190
                     /locus_tag="ACZPB4_12850"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family protein"
                     /protein_id="HIR1099137.1"
                     /translation="MKESKPVIFGSGASSSKDFKSLYINCHAALTNGITHFDTAPSYA
                     TEEVLSQAVQRSANELGLKRSDYQIQTKIDPIQMYNGKVVEYFKRKLETMRLDYIDSL
                     LIHWPVLKYLNPTWEELVMLKEQGLTRKIGICNLRINHLQELKVAHIIPEILQIERHP
                     LNIFDKEVLFCKENDIVLQDYSPLCKMHPKLKESTLLRALADKYQKDMGQIILKWHIN
                     TGAIPIFTSTKPQRISLYAHLDDFDLEESELFVISSLNDNYKLYLESLVCPGF"
     gene            16211..>16755
                     /locus_tag="ACZPB4_12855"
     CDS             16211..>16755
                     /locus_tag="ACZPB4_12855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099138.1"
                     /translation="MTLLWSMLVLFAFTPLWLFSILIALFFLILAVNNRLVLKLYEAH
                     KALSPKRTIPLYSTLLIGDLCAESVYKEYLSDNGKTLMLTAPRRSLEADYQILLHSVS
                     ALHENGTCIIIGSKYDKGISLFDVPYLSLTTRKELKVETLLRRSHYPLFFEPLRSLLY
                     FVSTNNKYYLKECPHPDMRKF"
BASE COUNT         4098 a         3733 c         4500 g         4324 t
ORIGIN      
        1 cgtttgacag agatcatgga tcgtgagcgt gcgaaccgaa actcaataca cctgtattgc
       61 acgggtccct actgggtagc gttcgagcgt tcggcctacc agctgcatcg tgcgttcccg
      121 gatagcgaga ccactccgtt gcgcctgttc gcctacccgt tcccgatcgt gatggtgtcc
      181 gttacggatc gctcgctccg ctcgtacgcc cgtaaacata tattgagaag agacgggtcg
      241 gattacaagc tattgaccgt ccccgggttt cccttggcgg actaccgtga atggcacgcc
      301 ggcgaggtgg agggattgcc ccggttaagc gagaattaga taagggcaga aaagaaacgg
      361 tcggatcccc cggatggcaa tggccgtctc tagcggctag gagacccctt ggctttggcc
      421 gataggctga ccccgcttta acatatacca ctccggccgt ccggtggtcc ggccctttta
      481 taattgagaa ttgaaaattg agaattaaag agatgataat agcggtagat ttcgacggta
      541 cgatcgtcga gcacaagtat ccggcgatcg ggcgtgagct tcctttcgcc atcgagacgt
      601 tgaggaaatt gcaatcggat cggcataagc tgatcctttg gacggtccgt gagggcgggc
      661 tcttggagga ggcgttgtcc ttctgccgtg agcgtggctt ggagttctac gcggtgaacc
      721 gtgactaccc ggaggaggag agagaccgga acaaccactt ctcccgcaag ctgaaggcgg
      781 acgttttcat cgacgaccgc aacctcggcg gcctcccgga ctggggcacg atctacgaga
      841 tggtgaccaa gggactgagc tatgaggact tgacgcgtaa atacgagtcg gaatacgagc
      901 cggagaaacc caaaggtttc ctgtcccgcc ttttccgtta agtccgtgtc atccgtgttt
      961 aaagaaataa aaacgataac aaaataatat gaagatcaaa agactactgt tcctattctc
     1021 gctgcccctt ttgctggcgg cgtgtacgtc ttacaagaac gtgccctacc tccagaaccc
     1081 ggaggcggtg aacgatctcg aggggacgct tcccctgtat gacgccaaga tcatgcccaa
     1141 ggacctgttg agcatcacgg tcaacacgac ggaccctcag gcggcggccc cgttcaacct
     1201 gacggtgcag accccgttga acgcggccct gacgaacatc aacacgacga cgcaacccac
     1261 gttgcagcaa tacctcgtga acaactccgg cgagatcgac ttccctgtga tcggtacgct
     1321 gagggtcggc ggcttgacga agaacgaggc ggagagcctg atccgtgaga gattgaggcc
     1381 ttacttgaag gaggcgccca tcgtgacggt gcgcatggcg aactacaaga tctcggtctt
     1441 gggcgaggtg gcccgtccgg gcagcttcac gatcggcaac gagaaggtga acgttctgga
     1501 ggcgttggcg atggccggcg acatgacgat ctacggcgta cgtgacaacg tgaagctgat
     1561 ccgcgaggac gagagcggga agcgcaagat catcaacctt gacctgaaca acgccggaat
     1621 cgtgacctcc ccgtattatt atttgaaaca gaacgacatc ctttatgtca cgccgaacga
     1681 gacgaaggcg aggaactccg atatcggtaa cagcacgacg ttgtgggtga gctcgatctc
     1741 gatcttggtc tcgatcgccg gcctgttggt gaacatactt aaataattga aaatagagaa
     1801 ttgagaattg aaaatttaga gagatggtgg acgatggtat aaatacaagc aataataata
     1861 ataataataa caatccggag ggggaggatc gtgagatcaa tctttacgcc gtgtttttca
     1921 agtatatggt ttattggcct tggttcgtgg cgagcgtact ggcctgctgc atcgggatgt
     1981 acgtcttcct gcgttaccag acgccggtgt ataacgtcac gtcgtcggtg ctgatcaagg
     2041 aggacgagaa gaagggggca aacgccgcca gcggcttggc tgcgatacag gaccttggca
     2101 tgctctcgat gacgagtaac ttcgacaacg aggtcgagat cctgaggtcc cgcacgttga
     2161 tcaagaaggt ggtgaacgac atgggcctgt atatcgacat ggaggagtcg aacgccttgg
     2221 gcttcaaccc ccctttatac aagaactccc ccgttaacgt gttcatcacc cccgaggagg
     2281 cggaccgtct ggtggccccc gtcgagctac gcatgcgcta cacgaaggag ggtcagctaa
     2341 cggtgagagc ggagtacaag atnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2401 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2461 nncttcaagc aacgctccgg cctgacgaat ttgacgagcg acgcccagat ggctttgcag
     2521 gaaagctcga ggtatgagca acaacgtacg gagaacgcca cgcagatcaa cttggtgcag
     2581 tatctccgca attatatcga cgatcctgcg aacatggacg aggtgatccc tgccaacgtg
     2641 ggcctgcggg atcaaaacct cacctctgtc atcgaccagt acaacacgat gatcatcgag
     2701 cgcaagcgcc tgttgcgtac ctcttcggac agcaacccgg ccatcatcaa catgaacgcc
     2761 ggcatcgagg ctatgcgccg caacgtgaag acgacggtga acagtgtctt gaagggtctc
     2821 cagatcgcca aggcggacat cgaccgtcag gcgagcaagt tcgagagccg catcagcgac
     2881 gccccgaggc aggagaagga gttcatgacg atctcccgcc agcaggagat caaggccacg
     2941 ttgtacatca tgctgttgca gaagcgtgag gagaacgcca tcacgctggc agccacggca
     3001 aacaacggcc gcatcatcga ggagccgctc gccgatgagc gtcctgtcgc cccgaagagg
     3061 atggtcttca tgcttgcggc gttgatcttg ggcctggcga tcccggtggg cattgtctac
     3121 cttcatgacc tgttgaaata caagatcgag aaccgtgagg acgtcgaggc gatcacgggc
     3181 gtggctatct tggcggagct cccgttggtc aagaagacgg gtgagggctc gatcgtggtg
     3241 cgtgagaaca agaacgacct gatggaggag atgttccggg ggttgcgcac gaacctcttg
     3301 ttcatgctag gcaaggacga gcgtgtgatc cttttcagct ccacgcaacc gggcgagggc
     3361 aagtctttcg tcgctggcaa cttggcggtg agcttggctt acttgggcaa gagggtggtg
     3421 gtggtcggca tggacatccg caagccgggc ctgaacaagg tgttcaatat ctcccgtaag
     3481 atggagggca tcacgaacta ccttagcgac cctgatcacg tggagttgtt cgacatggtc
     3541 cagcgatccg atatcagccc taacctcgat atcctcccgg gcggtcctat ccccccgaac
     3601 ccgactgagc tggtcgcccg tgacgtgctg gagaaggcta tcgcccggtt gaaggaacgc
     3661 tacgactatg tcatcttgga tacggcccct atcggcatgg ttacggacac ggcgatcatc
     3721 ggccgtgtgg ccgacatgtg cgtgtacgtc tgccgtgcgg acgtgacacc gaaggccggt
     3781 ttcagctaca tcaacgtgtt gcggcgtgag cgaaagttcc cgaagctcgc gacggtgatc
     3841 aatggcttgg acatgacgaa gcgcaagaac agctacggtt atggttacgg caagaaatac
     3901 ggctacggca agggatacgg ttatggctac ggctatggtt acggtttcga ggccggtgac
     3961 aagaagaaat aactaatacg caaatcatgc aaataacatt actattactg tcgggcttcc
     4021 ttttctccgt gctgttcggg atggtgatca tcccgaggat cttggtgatc tcccacaaga
     4081 aacggttata tgatgtcccg gattcccgta aggtacatac gacgccggtc ccccgtttgg
     4141 gcggcctgtc gttttttccg gtgatcctga tgtccatgtt ccttgtgata ggcttccgcc
     4201 tgtacttttg ggatatgggc tcatcgagcc tgtcgttcaa catgctctat gagtatctct
     4261 ttctgttcgt gggcatgacg ttactctatc tagtgggtgt ctgcgacgat ctagtgggtg
     4321 ttggctaccg ttacaagttt gccgtccaga tcgtgtcggc gttattattg gtactgtccg
     4381 gtaattggtt cggttccttg ggaggcttgt tcggtgtgta ctcggttccc gcttgggtgg
     4441 ggatccccgt cacggtcttt atcgtggtgt atatcacgaa cgctattaac ttgatagacg
     4501 gtatcgatgg cttggcctcc ggtttgtgta gcatcgccct gtcggtcttg agcgtgatct
     4561 tctttatccg catgcaatat gtttacgcct tgttggccat ctgtacgctg ggagtcctca
     4621 tgcctttttg gtgttacaac gtttttggca acgcaaaccg tggccataag cttttcatgg
     4681 gcgatgcggg tagtcttacg ctgggctacg tgatcagttt tctgatcatc catctgtgcg
     4741 tgtcgaatca agtcttaccg gagttaccaa atccctatat ggtgatcgct ttctccacgg
     4801 tcttggtccc tttactcgat gtaatccgtg tggtgcttca tcgtcttcgt aatcatcgta
     4861 acccgttctt gcccgataag aatcatttcc atcacaagct gcttcgtacg ggtatgcgtg
     4921 tacggatggt gatggtgacg atcttgtgcg tatctgtttt tttcatcgta ttgaatgtct
     4981 tattggccat gaaggtaaac gccacctacc tcttgctctt gaacttggtt ttatggtcta
     5041 tccttcattt gacgatcaac cgcttcataa cgaggcatca taaagagcaa gagctgaaag
     5101 agataggggg tatttttaca aagtaagtcg tgaaaccgga caatctagcg agtgaatgac
     5161 gagccggtat ctattttata agacgagata ctcctccctt gcgtcaaagc aagggcaagc
     5221 cttgcgtatg taagggctta attggtaatg tcctaggatg cgtgcctccg gatagtccct
     5281 tcgtaattgc cgtagcagat ccatcaaggt acaccgctgg gcgtaggtcc gggtatcagc
     5341 tggacggcct tgttcgtcga gtcctccctc gtaacatata ccgatacttt tgtcgttcca
     5401 tccggctgcg tgcgccccga tctgattgac cggccggcag cggtgtaatt ccccgtcccg
     5461 tgtgatatag aaatgatagc cgatatcggc gaatccccgt gccttgtgcg atgaacggag
     5521 cgcctccaca ggaaaatccc tgtcatatcg tgtggccgag caatgaatta caaggaggct
     5581 gacctccctg taattctggt agaaacaata aaccttaccc atgataattg aaattgaaaa
     5641 ttagagaata caggattgga tgccaagtgc tcctgcgatg gcggtagcta cggcgatgat
     5701 cactttgata atggtactcc atacggactt tttcatgaat tatgaatttt aaattatgaa
     5761 ttatgaatta tgaattagga atcccggctg atataagagg aaagcttggc tttcctttgg
     5821 acggcctcag cggacgggcg tcaagcgaag agaccgtagc gagcgtgagg agcatccctg
     5881 tctgagcgaa gcgagttggg atgcgacagc gagcgtaggt ctcgaagtag cccgtcagcg
     5941 tcagccttga ccttttggtt acttttgggt caagccaaaa gtgacacatc agatctcatc
     6001 aggcgactca gaatcggaac cgcccccttc ctccaccggc gtcccgagta tcgtcacctt
     6061 gagcaacgaa gtcttctcgc ccagcagcga gtagcgtcgt gccccgttca gtatggtata
     6121 ggaaggcgag aatcccggca cgatagtccg tatatgcgta gccttgacct cgggggcggt
     6181 cgctaccccc ttctccgtga cgaagcggtt atagacggtt ccgaacccta gcagctccac
     6241 cttgtaacct ttctgtaggt tcttgatgac ataccgctga taacgatcca atacgttcaa
     6301 tacgtcaccc ttcgtgagcg aagactcctc ggcgatctgg tcggccgcat cttgtgtgga
     6361 cagggtaccg aaataatagg gaaccggctt gtacacctcc tgcttaggat ccgtcttggg
     6421 gataaaaaac tttcgtgctt gaaatgcttg tggcatagtt tgataattaa agattaataa
     6481 tagaaaatta attgcttgct gatcaatgtt acaaagatag gttccgccgt aaggggcggt
     6541 gatgccgatt gatgcccggg gtagggaata acgattaatt aacatgggac gcagtgataa
     6601 ccgccggttt cttacgctgc ctatcgtaag cccctttgaa taggcattat aagaagcctt
     6661 ggatgggcat tgtaaagatc ttagaatacc catccaagtt gacagttgac tagtgacagt
     6721 aggctgtttt tatttacctc tgtgcgcaac tgtcaactaa tttacggttc tcctaggtag
     6781 tggatgatta atctgatctg tcggggcgtg aatatacgtt gctcggggcg gtagcccgtc
     6841 tccagcagct tgtcgtgcaa ttccgtgcat cgaatgatcc aacgacgtaa gcggttgcaa
     6901 gcttgatggg aggccagctc cgggaaatag gatgccgcta gtgcggactt tcttaatggc
     6961 aagaacattt gatttatgat ttatagattt gggagaatga aactttcaaa ctttcaaaca
     7021 ttcgtccccc cctcacacac acacgcccgt ggggtacgtt atataggggt gtgagggagg
     7081 ccgggattac ttatgggtga cacggccgcc gaagctgtac tcgccccggc cgttcttctc
     7141 cagcgtgcct cgttcctgca ttcgcttgag acaggtatct agggtggcgg tggggatgtt
     7201 gttcctctct gcttcctcca aggcctgttg tcggttgaaa gagagtggaa gggccgcgaa
     7261 gagagcctct tggggcgtgg gcgtgcgaga gcgtggcacc tcgtcagacg gaagcaggga
     7321 gagtatgccc gccgaatgac ggtagagcgg ctccacgagc gagaggacag ccttaaaatc
     7381 gtcatcgttg atacgtaact ctagggaagg aacgataccg tcccgtacgt tctcctccgg
     7441 gatctcgagg gcaggcgaga gaccgggaca attgaggatt gaaaactgag aatcgagaat
     7501 ggcttgtggg atgaggagac tctccaccga tcgtaggaag gccaccacgg aagcgatccg
     7561 gcagatattg atagcgatac gggccacgga gcttcgcatc ggatatccgt aggaaaggcc
     7621 ggcgtgcccg aatatgcgtg cgaagcagct gttgaatcgc tccttttgcg tgtcggagag
     7681 atggaattgt atgatattga ccctctcacg caggtagtcc acgagcattt tccactgctt
     7741 cccccaatcg gagaagaggc tatccatgtc ctcgtcgccc tgctcgaact gatccgccca
     7801 ctcgtcgatg ggtggcatcc ggtagaacaa ttggcgtgag aacaacccgt tctcggccga
     7861 gggaatgagt ggccgtacct gcgccggggt cccgcttaac aagacactga ggtaagaggc
     7921 cgggcactcc cggtattccc ggttcgtgcg tcggttgaaa gccagtcgct cgtggtcgtg
     7981 gcatttacgc aaggtatcgc tccagtgccc gtgctcggtg ccgatggccg tgctcacggt
     8041 atcggcctcg gtctcgcaga tcagccctat gccgtcggcc tcgatgaggt tctccagcac
     8101 gccggtgccg gaattgttac cggcgataag gaacatcttg aggggaggca tctcgggctc
     8161 cggcgtatcg gattttttct tgcccagcga gtcccaacgg ctcttctcct cccggtaagc
     8221 tttatgcctc tgccggtagt tcgccatcat cgcctcatgt atcggctcgg caagccggcg
     8281 tgtccaagcg agggctccct ttcccgaggc gggaggggcg acgatgaacg tttgcaggca
     8341 agggtagtag aattttcgcc cgtacgatat ccggatcgat ttgttgagtg tcgctcccaa
     8401 cacggtgata cctcccagca ggaggatatc cttttgggcg ggggtatcgc cccggtcgat
     8461 catccgtttg aggaaagcgg gccaaggata ctccggaaag gcgggcggga catttttcac
     8521 ggactgttcc tcgtgcgtac acgtgtgcgt gtgtgaagga ggcgtgaatg tttgaaagtt
     8581 tgaaagtttc ccggcctcgg ccatggattt gtccagtttc acgccggcta ggtccgccaa
     8641 gtggaatacg gatcccaagc cattccgtcc attgcctcct ttgagggcat ggtcgtatag
     8701 cttatccgcc tcggtagaga catatttctc cgacatccgg cagatacgat gaaagaatgt
     8761 ccggccggcc tctccgcaat cgttggcgat ggcgaaggcg atcggcatat actcttgata
     8821 ggtgggagcg atgttcgccc cctgtttctc gatggcggca acgagccgct ccagatctga
     8881 taatgggttc atgatgaatg aataatgaat ggtgaataat gatttataac taccaactgt
     8941 cacttgtcct ctgtcaacaa ttccggtctc ctagcctcgc tgagggatcg tggcaaagga
     9001 agcaagcccg tgagaggtct gcgttcgtgg catcagcttt cagcccgtat ttccactcaa
     9061 ggtattccca agcgaatcgt accgcctcgt cgaaagactc ctctacggtt ttcttgatcg
     9121 acaggcgata gggtacgagg agcttgattc ccgtggtact gggactcacg aaggagagat
     9181 cggggcgtag ccgctcatcg gcgaagagcg tgtccctcca acagatcgcc tcttcgggtg
     9241 aggagaggtg atcgatgtcg atgacgaact cgcccgaggg cacgagcaag tgatcttcct
     9301 tgcggtagga gaagataccg gcgggcgtga catagggtag caaactctgt ttcagccgcc
     9361 tgaaccgttt ctcgtcgctc gatgcggcac gtacctgatc ggtacgctca cgcagccact
     9421 cgctggtggt gatataggcg tacaattgac tgacacagac gaccccgttc ggtacttgat
     9481 tggtgatggg ggcgttgaaa aaggaaaaga tagactcttt catgatcgga taaaataaat
     9541 tgattattcg gttactgccg gtaaaggaat gcgttcctgc ccgttcccgg aatagcgatg
     9601 gacgggacgg gtacggaaac ggacgtatgg tggatgaaat gaggatagaa ataaatatcc
     9661 cccgtgaaaa gggtgattat tgttaacact taaattaaaa acggatatga cagaaaatca
     9721 agagcgggcg gaacaggcac gttctgcctt tacggtcaat ggaggtaacg tgcagatcct
     9781 gcccaatgcc accatcgcta tccagaacat ccattggggt gacgggacgg tgacacggac
     9841 ggaacgctgg attacgcccg cggaatcggg acttcatgag tctccgtctc ctccgataaa
     9901 ctctcctgcc cctccggtga cggctgaacc ctcctcgttg gcgttgttca tcccggacga
     9961 ggcgacccgt cttgtctacg aggcccgcct atgcgcctgc ccggacacgg tcaccctttg
    10021 ccaaacggta ttgacggacc tttacaacga gatcctagcc gactactcgt ctcccctcaa
    10081 gctggtcaag agccgtgcct tcatcagcgc cctcttgcct cacctcacgt tcgtgaacgg
    10141 ggcgaatgta ccgagcattc ggtatgggat caggaagtat gtgctggggg aagggtgaga
    10201 taaaaaagtg tgtgaatgat atagagaata ttcgtatgaa aggaatcgtt ttagctggtg
    10261 gctcgggtac ccgattatac ccgatcacta agggagtgag caagcagttg cttcctattt
    10321 ttgataagcc gatggtgtat tatcctatca gtgtgttaat gctggcgggt atccgggaaa
    10381 tcttgatcat atcaacgcca tacgatttgc ccggattcaa gcgtctgctt ggggatggct
    10441 ctgattatgg tgtgtgtttc gagtatgcgg agcagccatc gccgaatgga ttggcgcagg
    10501 catttactat tggtgctgag ttcatcggtg atgacagcgt ttgcttggtg ctaggtgata
    10561 atatcttcca tggtaatgga tttacatcga tgctaaagga ggcggttcgt actgctgaga
    10621 aggagaatag ggctactgtt tttggctatt gggtgagtga tccggagcgt tatggcgtag
    10681 ccgagttcga tcaggccggc aattgcctga gtattgagga gaagccggaa tgccctaaga
    10741 gcaactatgc cgtggtcgga ttgtatttct acccgaacaa ggttgttgat gtagctagca
    10801 gcattcaacc gtccgctcgc ggcgagtatg agattactac ggtcaaccaa cgattcttgg
    10861 aggatggaga gctgagagtc caaactttag gccggggttt cgcttggctg gataccggta
    10921 cgcacgactc tctgagcgag gcttctactt atatcgaggt gttggagaag cgtcagggat
    10981 tgaaagtggc ctgcttggag ggcatcgctt atcgtcaagg atggatcacg gaggagcgta
    11041 tgagagaatt ggcgcagccg atgttaaaga atcagtatgg tcaatactta ctgaaagtaa
    11101 ttgaggaatt aaaggagaca ggagatccga atttaggtta agatggaggt aataaagaca
    11161 gatatagagg gtgtagtgat cattgagccg aaggtgttcg atgacgctcg gggatacttt
    11221 ttcgagagtt tctcgcaacg tgagtttgag gagaaggttc gtaagataaa ttttgtacaa
    11281 gataatgaga gtatgtcctc atacggagtg atgcgtggct tgcatttcca gaaacctccc
    11341 tttactcaaa gcaagttagt gcgttgcgtg aaaggatgcg tccttgatgt agccgtggat
    11401 attcgcaaag gaagcccaac gtatggtaag catgtggctg ttgagttgag cgaagagaat
    11461 catcgccagt ttttcgtgcc tagagggttc gctcatggat ttgcggtatt gagtgagata
    11521 gctgttttcc aatacaaatg cgataatttc tatgctccgc aagcggatgg gggcatccgt
    11581 ataaaggatg agagcctagg catagattgg cggataccga tggacaaggt ccttctttcg
    11641 gagaaggaca taaaacatcc ttgtttggag gattttgatt caccgtttga ttatcatgta
    11701 aatttatacc ctgaatttga ataagatgaa tatattggtg actggtgcca acgggcagtt
    11761 gggaaacgag atgcgtatca tcgctcggga aagtgacgac cactatgtat tcacggatgt
    11821 gaatcaagtg gaaggcgtag agaccggctt tttggatatt acggatttgg aggcggtgag
    11881 gaagatggtc gcggcgcagc gtgtagatgt tatcgtgaat tgcgccgcct ataccaatgt
    11941 ggatatggct gaaagtaatg aggaattggt ggagaagttg aacgctgagg ctccggaaaa
    12001 cttagccaag gtaatgaaag agaccaatgg ttttttagtg caaatctcga cagactatgt
    12061 gtttggtaaa gaaccgtgca atgtgccttg tcaagaggat caacaaggaa cccccaccgg
    12121 agtttatggt atgagcaaat tgcatggtga gcagaagatt caagctatcg gttgcaagca
    12181 tgtgattatc cgtacggctt ggttgtacag tgagtttggc aagaacttct gtaagacgat
    12241 gatgaacctt acggctacca aaccacatct taaggtcgtg ttcgaccagg tgggaacacc
    12301 cacatacgcc ttggatttgg cgaaagccat tgagacggtg ttgaaagatt atgcggataa
    12361 aaaaaacgaa catgattatg acaagaccgg tatctatcat tactccaacg agggggtatg
    12421 ctcatggttt gacttcacga aatcgatcgc tgaatacaat ggcacgaccg cttgcgatgt
    12481 gcagccctgt catagcgacg agtttcccag ccctgtaaaa cgtccatttt attcggtatt
    12541 ggataaatct aaaatcaagg agacattcgg tattcggatc ccttattgga cagaatcgct
    12601 gagacaatgt attgctaaca taaaaaacaa ataaacagaa tcatgtcaaa acgaaatata
    12661 gtaatcactg gtggagcagg cttcattggc agtcatgttg tacgcttgct cgtgaataaa
    12721 tatccggagt ataacatctt caatttggat aagttgacct atgctggcaa cttggctaac
    12781 ttgaaggatg tcgaggataa gcctaactat aggttcataa ggatggacat ctgcgacttc
    12841 aaggcattct atcaattgat gcaggataag cagatcgatg gcatcattca tttggcggcc
    12901 gagagccatg ttgatcgttc cattaaagat ccgttcacct tcgcccaaac taatgtgatg
    12961 ggtacgctgg cgctattgca ggcagctaag ctgtattggg agagtctacc ggagaggtac
    13021 gagggcaaac gcttttatca tatctctacg gatgaggtgt atggagcgtt gaccatgaat
    13081 tatccggagg gcattgagcc accgttcacg acaacagcgt cgtccagtga acatcatttg
    13141 gcatacgggg atgatttctt ctatgagacg acaaagtata atccacattc gccctattca
    13201 gcgagtaagg caagttcaga ccattttgta cgtgcctatc acgatactta tggtatgccg
    13261 accatcgtga caaactgctc aaataactat ggcccctatc aattcccgga gaaactgatc
    13321 ccgcttttca tcaacaacat ctgtcatcgt aagccgttgc cagtctatgg caagggcgag
    13381 aacgtgcgtg actggctgtt tgtggaggat catgcccgtg cgatcgatac gatcttccat
    13441 cacggaaaaa tcgctgagac ctacaatatc ggcggtttca acgagtggaa gaatatcgac
    13501 atcatcaaag tgctgatcaa cacggtggat cgcctgttag gtagaaaaga aggggaggac
    13561 ttggatttga ttacctacgt gaccgatcgc ctcggccatg acgcacgcta tgctattgat
    13621 tccaccaagt tgcaaaaaga actcggttgg gaaccgagtt tgcaattcga ggaggggatc
    13681 gagaagactg tgcgctggta tttggataat caggagtgga tggataatat cacgagtggg
    13741 gagtatcaga ggtttaataa tctttaaaaa tcacagttta tccttacttg gtttttgact
    13801 agggataaat tgcccgctta taaatacctg cctacgttta tgtctactga gaatgtaatt
    13861 aacaaccaac gaatagcaaa aaatactttt ttattatatc tgcgtaccat ctttgtattg
    13921 gcggtatcat tgtacacaag tcgtctcgtg ttgaaggtgc ttggtgtgga tgactatggt
    13981 atttatcaag tagtcggagg tatggtgact atgtttggta ttttgtccaa tgcattgtct
    14041 gccgctatca gtcggtttat aacttttgag ttaggaagtg gtaaagcaga aagattaaag
    14101 aggttattct ctaccagcgt ggttgtacaa tatgtattgg cgggcatagt ctttatcatc
    14161 gcagaggttg ttgcgatatg gtttatggag acagagatgc aacttcctaa aggtagagag
    14221 tttgccgcta agtgtgtatt gcattgctca ctgttcactt tttgcgtgaa tctgataagc
    14281 attccttata atgcgtgtat cattgctcat gagcacatga aagcttttgc ttatatgagc
    14341 gttgttgatg ttgttttgaa attgattgcg tgtttgggag tgatgtgcat tccaatagat
    14401 aaattaatct cttactccat atttttagca gtcatctcca tttccataag aatactctat
    14461 tggctttatt gtaaaaagca ttttgaggaa actaggggat ctgttgcgtt tgactggtgc
    14521 atattcaagg agatgttagg attctctggt tggagtttct tgacaaacgc aaatggtatt
    14581 ttaaatacgc aaggtgtgaa tatgcttatc aatgtgttct ttggtgtgac agtgaatgca
    14641 tcgagaggta tatcttctca ggtagaaagt gcagtattgc agtttgttaa caactttaca
    14701 atggctgtga atcctcaaat tatcaaaagc tatgcggctg gcgatattca aggattatat
    14761 acattgatat gccggggggc taaattcgct tattttgcca tgttcatcat ggtgttacct
    14821 ttggtatgtg agacaccata tatgctaagt gtatggctga ctatcgtacc tccacatacc
    14881 gtgatatttg tgcagttatc tttaatattg ggtattttcg attgtatagg tttttcttct
    14941 tacacggctt gtatggcgac tggtagaata cgcttatatt ccataacctt agccattatt
    15001 ggagcattgg aattcccttt aacatggata ttttttactt atggtgctcc agttgtctct
    15061 acctattact tatacatatt tgtaaagatc ttagtgctta tagctagagt gatactgttg
    15121 cgtgatatgg tcggtttgcc accccaaatg tatataatag aagtgttaat tcctattctg
    15181 ctcactacac tcatagcgat aattccttct ttactaataa taagcttttt tccgtcatca
    15241 tttgttcgtt tatgtatttc ggtgattgtt gccattattt ctgtcggttt atccgctctt
    15301 tatataggca tgacccaaag ggaaagggaa gtgattctgg agaaagtcaa tagtgtggtt
    15361 aatcgattaa aaaaatgaaa gagagtaaac ctgtcatatt tggatctggc gcttcatcaa
    15421 gcaaggattt taaaagtttg tatatcaact gtcatgcggc gttgactaat ggaattaccc
    15481 attttgatac tgctcccagt tatgctacag aagaagtttt gagtcaagca gtccaacggt
    15541 cggcaaacga gttggggctg aaaagatccg actatcaaat tcaaacaaaa atagatccta
    15601 ttcagatgta taatgggaaa gtagtggagt atttcaagag aaaactggag actatgcgat
    15661 tggattatat cgattctttg ttgattcatt ggccggtatt gaagtatttg aaccctacat
    15721 gggaagagct ggtcatgctg aaagaacagg gattgactcg aaagattggt atatgtaatt
    15781 tgcggatcaa tcatttgcaa gagttgaaag ttgcgcatat cataccggag attcttcaaa
    15841 tagaaaggca ccccttgaat atcttcgata aagaggtgtt attctgtaaa gaaaatgata
    15901 tcgttcttca ggattattca cctttatgta agatgcatcc taaattgaag gagtcgacac
    15961 tgctccgtgc gctggctgat aaataccaga aagatatggg tcaaattatt ttgaaatggc
    16021 atatcaatac aggtgcgatt cctatcttca catcaaccaa accgcagcga atttcccttt
    16081 atgctcattt ggatgatttt gatttggagg aatctgaatt gtttgtcata tcctcactaa
    16141 acgataatta taaactctat ttggaatcat tggtatgtcc tggattttaa gaaataaaag
    16201 gaaaataatc atgacgttgc tatggagcat gttggttctg tttgctttta cacctttgtg
    16261 gttgttctcc atattgatag cactcttctt cttgattttg gcggtaaaca atcgcttggt
    16321 cctaaagctt tacgaagctc ataaagcctt gtcgcctaag cggacgatcc ctctttattc
    16381 aactctatta atcggtgatt tatgtgccga gagtgtttat aaggagtatt tgagcgacaa
    16441 tggtaaaact ttaatgctga cagccccaag aagaagtctg gaggcggatt atcaaatctt
    16501 gcttcactca gtctctgcct tgcatgagaa tggaacatgt attatcatag gatctaaata
    16561 tgataagggg atcagcttgt ttgatgtacc ttatttaagt ttgacgacac ggaaggaatt
    16621 aaaggtagag actctgctac gcagatcgca ttatccttta ttctttgagc ctttgcggag
    16681 cttgttatat tttgtttcca caaacaacaa atactatctg aaagaatgcc cacatccaga
    16741 tatgaggaaa ttctg
//
LOCUS       DBMDTB010000086        16584 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_1114_length_16584_cov_8.985743, whole genome shotgun sequence.
ACCESSION   DBMDTB010000086 DBMDTB010000000
VERSION     DBMDTB010000086.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 16584)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 16584)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16584
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1114_length_16584_cov_8.985743"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..1107
                     /locus_tag="ACZPB4_12860"
     CDS             <1..1107
                     /locus_tag="ACZPB4_12860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4933 domain-containing protein"
                     /protein_id="HIR1099139.1"
                     /translation="AMLKLSQIASKLEYYNVGDARYTVTQAIAIPDSDAFITFNNPRI
                     YYRKQGIPSKRYGFKALDYKWNHGMNGLNLFYDRKTTRMYCALSDLDQDNKKDSTTFN
                     DIRPCIGELPTLDTMLTIQNYIFPENLPTKYSINADASQIVGFSSSGYMLCDYAEGSK
                     IPKGITTFNLRGDTLCKFILADAKDINVSPDTITRFQTFYWNTDQDRINFLIPYRDTV
                     YQLSSSHSITPLYALHKDNQDKPTGLRSFLENPNGLFMGVFQKGSPAIYNWLGWLDDY
                     KPVITHRVVYLKKEKKTYALPKSSGGFINDIDDGLPFWPDGQTDDCVYMIRTVTEMRE
                     TVKRTGSSRQKDLIKFLDDPKVFERDYVMIVARP"
     gene            complement(1115..2287)
                     /locus_tag="ACZPB4_12865"
     CDS             complement(1115..2287)
                     /locus_tag="ACZPB4_12865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009016865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HIR1099140.1"
                     /translation="METLFRSFRTQLEHTSTEVVRFLHDQIAWDSRLVAILGARGVGK
                     TTLLLQHIKLYDREDESLYVTADDFYFTKYRLFDMAYQFYNLGGKKLYIDEIHKYKDW
                     SREVKNIYDQIPGLQVIYTGSSILDLEKGGADLSRRKVEYRLPGLSFREYLNISQGWQ
                     LPSYSLEEILAGKVEFPYKEARPLKLFNDYLSTGYYPFFQDTEYLLRLRSVINQMVES
                     DIPIFADMTVASAVKLKKLLYVLAQSVPFKPNYTKLARDLDISRNVLPDYMSYLEKAG
                     LVNLLREKAQGLKLLEKVEKIYLNNTNLAYALSEQVPDIGSVRETVFLSWMRVVCFVT
                     SSAISDFEIDGRTFEIGGKNKTRQQIKQAADGYVVKDDIEYAFRNMIPLWMFGFIY"
     gene            3059..5041
                     /locus_tag="ACZPB4_12870"
     CDS             3059..5041
                     /locus_tag="ACZPB4_12870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HIR1099141.1"
                     /translation="MKLFWITLLISSLVSCHNFKEDRQLSFALERAGENRRELEQVLE
                     HYKNDSLKYRAACFLIKNMPGHYSYCGKITNTYNKQIDSIILQTQKEGRYHDTPYLAN
                     RIDRISKIHENTSFPIQEDIRIITADFLIQNIEQAFHLWEDAPWSRHLNFDDFCEYLL
                     PYSIGAMDVLEDWRTGMYQQIDSTTLTELNDFSYSSDMQNSAFWACKHINQFLEKKLV
                     PENSVYSIPFIAKTSTRSMISFGTCNQFSLIALAMMRSIGIPVMLDFTPQWPFRSMGH
                     YWNVLLDNTGKNLAFGGCETKTDPDILHKPSQKMAKVYRRTYAINQDLVKLNTTEEVV
                     PDLFRNIFMKDVTSEYMKTCDIMIPTQKKRNHKHAYLAVFDNQKWVPICYGTQKGKVC
                     YFNEIGKDIAYLPLYYDNQGIHPITDPFILDSRGRIKYLHADTSKRKKVILSRKYYLA
                     KHIFDYAKTLTGGHFEASNNPDFSDPDTIHTISHWLLSADSFEIKPQKTYRYWRYVSA
                     KNKGCNLAELAFYSDKEEKELTGTIIGTNASVRYDTMPMDKSKVFDKDILTYYEAPST
                     VDYPWVGLDFNKPVSINKIIYTPRNDDNNIHAGDLYELFYWEYNHWMSLGQQRAIESK
                     LTYTNVPDNALLLLKDLTKGEEERIFTYENDKQVWW"
     gene            complement(5281..6270)
                     /locus_tag="ACZPB4_12875"
     CDS             complement(5281..6270)
                     /locus_tag="ACZPB4_12875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HIR1099142.1"
                     /translation="MEKQNWKWSVFVLMTMICLLSFYKSYQNVKYELQEESQTLFQRA
                     VQDDTNRRIKDLGDAFCFSYSGANRLERDSITIKTADAIIHMRNNKEVARRMSSQEKS
                     DFCLQHCLSMENPIQVTLLDSAFRASLYEHAISAQTVTCYTFIDKTECSSSDTSFYQS
                     FIPLKDIVFGANRTIVLQAFVQFPFLYIVGEVFLRNIFWILAMVILWVIAIVLTWKRP
                     RINILPLQEAPKEMIQITEDILFDETHGVLHYHRHRIELANQRLKLFCILLEHKGYFI
                     ESNRLKEEIWPDGSVSKDALTATAKRLKEDLSPIPDLVIESARGHGYVLKCGG"
     gene            6463..6681
                     /locus_tag="ACZPB4_12880"
     CDS             6463..6681
                     /locus_tag="ACZPB4_12880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NVEALA domain-containing protein"
                     /protein_id="HIR1099143.1"
                     /translation="MKQITFKKAFAIIFICALCASYFLLKEGKQNFSDLTFSNIEALA
                     SGESGSKDCYMAGSLSCNGGYYKYIYNR"
     gene            6690..7739
                     /locus_tag="ACZPB4_12885"
     CDS             6690..7739
                     /locus_tag="ACZPB4_12885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TolB-like 6-bladed beta-propeller
                     domain-containing protein"
                     /protein_id="HIR1099144.1"
                     /translation="MNYYVYIVLLIGSLVSCSESSRHFPRYEDFPDEKVLNAQVIHLD
                     TALFRYPFRIAVKDGIAIIMDLHNVDYFFHAFSYPEWEYMTSFGKRGEGPEEMVSADC
                     FRFISKDSIWTLDANKMRTTRWKIEQNMNNIIPVETIDMDKRLVRALDFYPMESGFLV
                     SDYLGEYRQKWTDREGKWIHSANQIPTENNYEDIARPALAQAWRSFFDYNPQKGILVM
                     ATQLGEALEIYNFTDTTQTVRYGPNGEPQFAISQSEGIPTGIMGFSDVHITDHFIYTV
                     FHGRSFKDIGQAYQRGEDIEDGGRYIYVFDLKGNPVRKYVLDHAIYGIDVDEDTGTIL
                     ATDVNSNDPILSFKI"
     gene            7752..8606
                     /locus_tag="ACZPB4_12890"
     CDS             7752..8606
                     /locus_tag="ACZPB4_12890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1573 domain-containing protein"
                     /protein_id="HIR1099145.1"
                     /translation="MKYLNLIILLLFLLACQDKKKDEIKHLVSEWQGKEIRFPKDMVF
                     ARFATDTVDFTLPKSPHKVLVFVDSIGCTSCKLQLHRWKELIQYTDSITQGTVPFLFF
                     FQSDDKKEIRYLLKKDNFDKPICMDQSDRLNELNHFPADGRFQTFLLDKDNKVVVIGN
                     PIHNPNIRELYLKEITGKQPASQIQTTVKVEEASIQLGTIQMGESKEAVFRLTNTGNN
                     PLVILDAATTCGCARPSFDKHPAKPGEILQVRVIMTPKDKGVFDETISVKCNTNQLIK
                     LNIRGMAQ"
     gene            8813..9043
                     /locus_tag="ACZPB4_12895"
     CDS             8813..9043
                     /locus_tag="ACZPB4_12895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NVEALA domain-containing protein"
                     /protein_id="HIR1099146.1"
                     /translation="MRKKILGIAVMAVVAVAAAWNINQSENEIKLSDLALDNVEALAS
                     GEGGSGYCSYSGGGCIIKYSDGTSTYIPGRWN"
     gene            9231..10283
                     /locus_tag="ACZPB4_12900"
     CDS             9231..10283
                     /locus_tag="ACZPB4_12900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BF3164 family lipoprotein"
                     /protein_id="HIR1099147.1"
                     /translation="MKKYIILHLSLILLVFIACTDDQKQDDKNITFQRSDFKVRKSLS
                     GKTIEFDSLILRPSQIQLFDSFLVTCNQGAEKQFHIFNLNTAHKEGECIPVGQGPKEM
                     MTPCFVNRNDSVVIFDMMTSTIFTYSIPEFTSGKEPEYASRISLDTKPLWSNIRSLGN
                     GFLGVSYQETSPGFLFDQTGKKTMDFGTYPKTEQEYTPAELINAFRADLTTNRKEKVA
                     ITHYFTDLICIYNVNGTLEKQLRGPDHFASVFKEFRDGDIIGSKASPQTYRDAFYSPV
                     NVGNSLFVLYNGKMVTEPNYNILCKELFVIGWDGSLECHYTLDQGVSSIAVDNQKRKI
                     YGISDDPEYHIVVFDY"
     gene            10379..11239
                     /gene="lepB"
                     /locus_tag="ACZPB4_12905"
     CDS             10379..11239
                     /gene="lepB"
                     /locus_tag="ACZPB4_12905"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HIR1099148.1"
                     /translation="MLRYLTLIFYGVFGIGCIYAFLLIFCFSTFKIPSDSMEPQLQTG
                     DQVLVNKWIAGPRLFNIFASMKGKRVDIYRVPGVGQIKRNDILVFNYPHPYSWERIEM
                     HIMQYYIKRCLGLPGDSIRIEQGFYRNNHTKEPLGNVESQANLSRQKADRMPDGVYRC
                     FPFDSTFNWNVHDFGPLYIPRKGDRITVNQTNYKLYKQMIEWESKDSLSWKDSKVYIG
                     DKQVRQYQFQSNYYFVAGDKTENSRDSRYLGLIPEEFIVGVAWKVWKSVDPYTGEYRK
                     GRFWKNIRNN"
     gene            11246..12655
                     /locus_tag="ACZPB4_12910"
     CDS             11246..12655
                     /locus_tag="ACZPB4_12910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HIR1099149.1"
                     /translation="MNKLILYVCAWICLHSCGFSKSQEESMLEYALSQAGDNRKELEY
                     VIKYYEGDSLKREAARFLIRNMVYHFGYEKRERVSDITTLSSDYLIRNIELAFQAWPK
                     PWNKSVSFENFCRYILPYRGLYEPPSGLREELMRTYLPLLDSSHIDNTYDAAVRLQKI
                     LRTRVTYQTEIPIHYPTAEEIHRTGVGRCDGVVLYGIQLMRAAGIPTVAEHTIWTRRN
                     GEHYWCAFLNEDGRFLPFAPEYEGPDSLIYNLTKPFLTPAKVYRYGFAPLHPVTTEST
                     DEYRTFLKNPLLTAVTEQYLPPVADIHTTCDLPVRSKRAPIYLCTYNHGNWRPFAMSE
                     RIGNRCTFPKIVGDDVFIIAEYDKEAYGSLRFITSPFHVSNTGIITKIKPDPARTDSI
                     FIASDNPYQQQVPYTLAYWEQEQQCFKNGYFPTDTIPGGILIRKIPKGSLLKAMISRP
                     EKAAEDRIFLVENGTVKRY"
     gene            12658..14466
                     /locus_tag="ACZPB4_12915"
     CDS             12658..14466
                     /locus_tag="ACZPB4_12915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HIR1099150.1"
                     /translation="MKELLKLGVYTLLGTLLLSAPFAGLGMLSTHLVTEKTFWIQLIT
                     LFLSAVSLQGLWLNPSKELCPWTYVDILPLSLLGLILLSYPYSIHPEPEKLLFIGQMV
                     VLWYLLRQVLHECPVLIGYFSMFFIATGLIEAIWGFRQLQGWAYSNHSLFRLTGSFFN
                     PGPYSGYLAITLPVALGILLEQSKRNMPYYLSMGCIGTAIVVLPAGMSRSAWIAVVVS
                     CAWVYALYRLDRKQAATRLRQHKRWYIIGGILGGILLLGGSASLYTLKKDSADGRFLM
                     WKITTKAIQKQPITGTSLGGFPAAYAETQAEYMASGKATEQEKLVAGCPEYAFNEYLQ
                     IGLEQGLVGLALFIGWLGLLFYKGIKNKRYACCGGLMSLAIFAFSSYPLQLPEFWVVL
                     IFLGVMSVTPDKDEIRENQAESNGHRWGKQIFFMGIAILGIGLFWMQKDHYKAYQQWN
                     KAQMYYKNKAYEAALEVYEPLYPLLKHKPEFLFEVAQCLSKTGRYEKANGYLERAVLL
                     SSDPMLYYVMAKNEQCLGEYRQAEKHLLHAIDILPERIYPYYLLMNLYTEPSYFQPAK
                     LKMAIDSVLTKKPKVESSAIKEMKEKARSMLNNTSI"
     gene            14567..15634
                     /locus_tag="ACZPB4_12920"
     CDS             14567..15634
                     /locus_tag="ACZPB4_12920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HIR1099151.1"
                     /translation="MKYYKLLTFTLLFCLSACGGEKKDTDTTQDSVETVLPDEANEVT
                     IMTLKQTEFNHELISNGKLSARKLVDLQFESAEPIARIYVKNGDRVNKGQKIAELATF
                     RLTNKTAQAKDALEKARLELKDVLIGQGYMLEDSAKVPPATLNLARVKSGYDLALAQY
                     QLAQYEEQNATLIAPFDGIIANLFAKQENVASTTDAFCTVIDPHSLEASFTVLESELP
                     LIQNGDKVEVTPFATTSLKTEGRISEINPLVDENGMVQVKAAVNDKGKLFEGMNVRVS
                     VQRSLGKQLVVPKTAVVLRSGKQVVFTLVDGHAYWNYVRTGLENADSYTLLEGLKEAD
                     VVITSGNINLAHESPVKVIKN"
     gene            15662..>16584
                     /locus_tag="ACZPB4_12925"
     CDS             15662..>16584
                     /locus_tag="ACZPB4_12925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HIR1099152.1"
                     /translation="MIRFLLQRPIAVLMAFTACFIVGLVTYFTIPVSLLPDIAIPEIT
                     VQISGQNTSARELENTVVKPVRLQLMQVAGLRDIHSETRDGAGIIRLSFDFGTNTDLA
                     FIEVNEKIDAAMNYLPREVERPRVVKASATDIPVFCLNLTLKTIENDAAFLDLCQFAE
                     TVIKRRIEQLPEVAMVDITGILGRQLQIVPDMKLLDMADITLNDLESALSANNIEPGS
                     MTVRDGYYEYNIKFSTLLRTPEDVQNIYIRKNDRIFQIKDLAKVAVVPEKETGLSLAN
                     GKRAVTLAVIKQADENMDNMKEALAEVTDYF"
BASE COUNT         5285 a         3590 c         3364 g         4345 t
ORIGIN      
        1 gcgatgttga aactgagtca aatagcctct aagctggaat attataatgt tggagacgct
       61 cgttacacgg taacacaagc gatcgctatt ccggatagcg acgctttcat cacattcaat
      121 aacccacgta tttattatcg taagcaaggc attcccagca aacgatatgg atttaaggcc
      181 ttggattata aatggaacca tgggatgaac ggccttaatc tattttacga caggaaaaca
      241 acccgtatgt actgcgcctt gagcgacctc gaccaagaca ataaaaaaga ttcgaccaca
      301 ttcaacgata taaggccatg tatcggggaa ttacccacat tagatacgat gctgaccatt
      361 cagaattata tattccccga aaacctgcct accaaatatt cgataaatgc ggatgccagt
      421 caaatagtag gcttctcctc ctcgggatat atgctttgtg attatgcgga aggctctaaa
      481 atcccgaaag gaataacgac attcaacctt cgaggagata cgctttgcaa attcatcctt
      541 gcggatgcca aagatattaa cgtctctccg gatacgatca cccggtttca aaccttttat
      601 tggaatacgg atcaagaccg aataaatttc ttgattcctt atcgagatac ggtataccag
      661 ctttcaagtt cccactcgat caccccttta tatgcgcttc ataaagacaa tcaagataaa
      721 ccgaccggtc ttcgttcttt cttggagaat ccgaatgggc tatttatggg agtctttcaa
      781 aaaggttctc ccgccatcta taattggctg ggatggctgg acgattacaa accggttatc
      841 acccatcgag tagtctatct caagaaagag aagaaaacat acgccttacc caaaagctcc
      901 ggaggattta tcaatgatat agatgatgga cttccgttct ggccagacgg acaaaccgat
      961 gactgtgttt atatgattcg caccgtcacc gaaatgcgtg agaccgttaa acgcacaggc
     1021 tcctcccgcc aaaaagacct gatcaaattc ttagacgatc ctaaagtgtt cgagagggat
     1081 tatgtaatga tcgtggcaag accttgatgg atattcaata gataaagcca aacatccata
     1141 aaggaatcat attgcggaaa gcatactcta tgtcatcttt caccacatac ccatccgccg
     1201 cttgcttgat ctgttgccgc gtcttattct ttcccccaat ctcaaaggtt cggccatcta
     1261 tctcaaagtc tgaaatcgca gaagaagtaa cgaagcatac gactcgcatc caagatagaa
     1321 aaaccgtctc acgcacggaa ccgatatccg gtacctgctc cgacaacgca taagccagat
     1381 tcgtattatt cagatagatc ttctctactt tctccaataa tttcaagccc tgcgcttttt
     1441 ctcgcagtaa attaaccaga cctgccttct ccaaataact catgtagtcg ggcaacacat
     1501 tccggctgat atccaaatct ctcgccaact tcgtataatt tggtttgaaa gggacacttt
     1561 gagctaatac atataataat ttcttcaact ttacggcaga agccaccgtc atatccgcaa
     1621 aaatcggaat atcagattcc accatttggt taatcacgct acgcagacgc aagagatatt
     1681 ccgtatcttg aaaaaatgga taataacctg tcgataaata atcattaaat aatttgagtg
     1741 gacgagcttc cttataaggg aactcaacct tcccagcaag aatctcttcc aacgaatacg
     1801 atggaagctg ccacccctgc gatatattca aatattcccg aaaagaaagt ccgggtaatc
     1861 tatactctac cttcctgcga cttaaatccg caccaccttt ctccagatca agaatagacg
     1921 aacctgtata gataacttga agaccaggaa tttgatcgta tatattcttc acctccctag
     1981 accaatcctt gtatttatga atctcgtcaa tataaagttt tttcccaccc agattataaa
     2041 attgataagc catgtcgaat aaccgatact tggtaaaata gaaatcatct gccgtaacat
     2101 acaaagactc atcctcacga tcatacaatt tgatatgctg caacaatagg gtagtcttcc
     2161 caacaccacg agcacctaaa atcgcaacca atcggctatc ccatgcgatc tgatcgtgaa
     2221 gaaaacgcac gacttctgtc gaagtatgct ctaattgagt tctaaaggaa cgaaataagg
     2281 tctccatatt gattcatgtt taaaggacaa atatacaaaa ttgcacgatg cgatgtgcaa
     2341 ttttcataca aaattgcacg atgcgatgtg caatttcctt tatataggtt gaccatgttc
     2401 tatcctattg atgaacgagg tttacccgga caaaaataat taacattgtt tgcacaaatt
     2461 cattcaactc acgatataaa taggtgacct tagattggca atcctaagag caatactgac
     2521 ttggctaagt aatatatact gacttgcccg acacagtata tattacttag ccaagtcagt
     2581 actactgccg atagcaagct catcacacaa ataaaccatc aaatgaacgt tgaaatggag
     2641 aatttactct cccgaaacga tctttagtga atatccttta ccccgagcac tctctatcac
     2701 caaacccgga ataggagaca aatcctcttt aagcctttta gccgtaacgg taagatgcac
     2761 gaaaagtact atctaatgat aatatctgaa gtgccccccc tgtataagaa aaacaaaaat
     2821 catccccaag ttctttgata cgccgatctg tatcctcttg gactacctgt tgaaatgata
     2881 gcaatacaaa tacataactt tatgccaaca aaccctcatt ttttgtctgt cagctaaaag
     2941 tcagctaaaa caattggcca tgaaaaggaa taaacttatg tttgtgaaaa attaaatacg
     3001 atatgaaacg agcaatctat taaaacaccg tccttcgcaa aaagaacaaa taaaacgaat
     3061 gaaactcttt tggatcacgc tacttatatc tagtttagtc tcttgtcaca atttcaaaga
     3121 agacagacaa ctctcattcg ctcttgaaag agcaggcgaa aaccgccgtg aattagaaca
     3181 ggtattggaa cattacaaaa atgattcctt gaaatatcgt gcagcttgct ttcttattaa
     3241 gaatatgccc gggcattatt cttattgcgg gaaaatcacc aacacatata ataaacaaat
     3301 tgactctata atacttcaaa cacaaaaaga ggggcgttat catgatacac cttatcttgc
     3361 caatcgcatt gatagaatct ctaaaatcca cgagaacacc tcattcccga tacaagaaga
     3421 cattcgtata attacagctg attttcttat tcaaaatatc gagcaggctt tccacctatg
     3481 ggaagatgcc ccttggagcc gacatttaaa ttttgatgac ttctgtgaat acctattgcc
     3541 ctactctatc ggagccatgg atgtactgga ggattggagg actggcatgt accaacaaat
     3601 agattctacg acattaacag aactcaacga cttcagctat tcttccgata tgcaaaactc
     3661 agcattttgg gcttgtaagc atatcaatca gtttttagag aagaaattag ttcctgaaaa
     3721 ctcggtatat tccattccgt tcatagcaaa aacctccact aggagcatga tatcattcgg
     3781 cacttgtaat caattctcgt taatagcgtt agctatgatg agaagcatag gaattcccgt
     3841 catgctagat ttcacaccac aatggccttt ccgctcgatg gggcattatt ggaatgtact
     3901 tttagataat acaggaaaga atctagcgtt tggaggatgc gagacaaaaa cagatccgga
     3961 tatactgcat aaacctagcc agaagatggc taaagtgtat aggcgaacat acgctattaa
     4021 tcaagatctc gtaaagctga atacaaccga agaggtcgtg cccgacctct tccggaatat
     4081 tttcatgaaa gatgttacct ccgaatacat gaaaacttgt gatatcatga ttccaacaca
     4141 aaaaaaacga aaccataaac atgcctacct agccgttttc gacaatcaga aatgggtacc
     4201 tatatgttac ggtacacaaa aaggaaaagt ttgttacttc aatgaaatag gaaaagatat
     4261 tgcctatctc ccactttatt atgacaatca aggtattcat cctattacag atccattcat
     4321 acttgattca cgaggtagaa taaaatatct acatgcagat accagtaaac gaaagaaagt
     4381 tatattatct aggaaatact atctcgcaaa acatattttc gattatgcaa aaactctcac
     4441 cggaggacat tttgaagctt ccaataatcc ggatttctcc gatcctgata caatacatac
     4501 gatttctcat tggttattgt ccgcagattc tttcgagata aaacctcaaa aaacatatcg
     4561 ctattggcgc tatgtatcag caaaaaacaa gggttgtaat ctagccgaac tcgctttcta
     4621 ctcagacaag gaggaaaaag aattaaccgg cacaatcatt ggaacaaatg cctcggttcg
     4681 ttacgatact atgccaatgg ataaatccaa agtatttgac aaagatatcc taacttacta
     4741 tgaagcccct tctacggttg attatccatg ggtaggcttg gacttcaaca aaccggtatc
     4801 tatcaataag atcatttata cgccaagaaa cgatgataat aacatccacg caggtgatct
     4861 atatgagcta ttctattggg aatataacca ttggatgtca ttaggccaac aaagagctat
     4921 tgaatcaaag ctaacctata caaatgtacc agacaatgct ctcttgttgt taaaagactt
     4981 aaccaaagga gaagaagaac gcatattcac atatgaaaat gacaaacaag tttggtggta
     5041 atctttatta ttccatgaga accatattaa attaattaca acaagtaggc aattttaatt
     5101 ttatctataa ataactgata atcagcgtgt aaaaaacatc attatatttt ccgaaaaact
     5161 cgtacgtgtt tttactaaaa gtcgtacgtg tttctaaaaa ttcacgtacg tgttttttag
     5221 aagacgaagt cgagaagaat ataaacattc aaaaaaatac actaacccac cttgtaaaac
     5281 ctacccacca cacttcagca catagccatg cccccgagca ctctcaatca ccagatccgg
     5341 aataggagac aaatcctctt taagcctttt agccgtagcg gtaagagcgt ctttggacac
     5401 acttccatcc ggccagattt cttctttcag ccgattagac tcaatgaaat atcctttatg
     5461 ttctaataaa atacaaaaca gtttcagccg ttgatttgcc aattcgatac gatgcctatg
     5521 ataatgcaat acgccatgtg tttcatcgaa caagatatct tctgttattt gtatcatctc
     5581 tttaggtgct tcttgtagcg gtaagatatt tatccttggt cttttccatg tcaagacaat
     5641 cgcaataacc cagagaataa ccattgccag aatccaaaat atatttcgca aaaacacttc
     5701 acctactata taaaggaaag gaaattgaac aaacgcttgt aaaacgatcg tccgattcgc
     5761 tccaaaaaca atatctttta atggtatgaa agattgataa aaagaagtat ctgaagagct
     5821 acattccgtc ttgtctataa aggtataaca agttacggtc tgagccgaaa tcgcatgttc
     5881 atacaaagat gcacgaaaag cgctatccag caaggttact tgaatcggat tctccataga
     5941 caaacaatgt tggagacaaa aatcagactt ctcctgtgaa gacatcctcc gtgccacctc
     6001 cttattattc ctcatatgta taatcgcatc ggcagtcttg attgtaatgc tatctcgttc
     6061 caatcgatta gcgcctgaat aggaaaaaca aaaagcatcc cctaaatctt ttatccgcct
     6121 atttgtatca tcttgaactg cccgctgaaa taacgtttga gactcttctt gtaattcata
     6181 ctttacattt tggtatgatt tataaaaaga caacaagcaa atcatcgtca tcagaacaaa
     6241 tacactccac ttccaatttt gcttctccat aattattcct cgttgaaact gcaaagatac
     6301 gttttccatc cctttctacg aataaattca ttcaactcgc aagatgaaag atgactatag
     6361 gtagacaaaa ggcttatttt tcaactgtca gctaaaagtc acctaaaaag attggctatc
     6421 caaagaccaa gccgtacgtt tgtaacaaaa attagaaacg acatgaaaca aattactttc
     6481 aagaaagctt tcgctatcat tttcatttgc gccttgtgtg cttcgtattt tcttttgaaa
     6541 gaaggaaaac aaaatttctc agatcttact ttctctaata ttgaagcgct agcttccggt
     6601 gaaagtggat ccaaagattg ttatatggct ggctctctat catgtaatgg aggatattac
     6661 aaatatatat acaaccgtta aaacaacaca tgaactacta cgtgtacata gttctattaa
     6721 taggtagtct ggtatcctgt tcggaatcct cacggcactt cccccgctac gaggattttc
     6781 ccgatgaaaa ggtattaaat gcgcaggtta tccacctaga taccgccttg ttccgctatc
     6841 cattccggat agcggtcaag gatggtatcg ctattatcat ggacttgcac aacgtagatt
     6901 atttcttcca tgccttctct taccccgaat gggaatatat gacatcgttt ggcaaacgag
     6961 gcgagggacc cgaagaaatg gtatcggcag attgcttccg gtttatctcc aaggattcta
     7021 tctggacgct cgatgcgaac aaaatgcgaa caacccggtg gaagattgaa caaaatatga
     7081 acaacatcat tcccgtagaa acgatcgata tggacaagcg gctggttagg gcattggact
     7141 tttacccgat ggaatcgggc tttttagtat ctgactacct cggtgaatat agacaaaagt
     7201 ggacagaccg agaagggaaa tggattcact ccgctaatca gatcccgacc gaaaataatt
     7261 atgaagacat cgcacgccct gcattggcgc aagcgtggcg aagcttcttc gactataatc
     7321 cccaaaaagg catcttggtc atggcaaccc aactaggaga ggcattagaa atatacaact
     7381 tcacagatac tacacaaacc gtacgatacg gacctaatgg agaacctcaa ttcgcaatct
     7441 cacaatcgga gggaattcca acgggtatca tgggattcag tgatgttcat atcacagacc
     7501 atttcattta taccgtattt catggccgta gtttcaaaga tatcgggcag gcataccaac
     7561 gaggggaaga tatcgaggat ggcgggcgat acatctatgt attcgacctc aaaggaaacc
     7621 ccgtccggaa gtacgtgctc gaccatgcca tttatggtat cgacgtagat gaggatacgg
     7681 ggacgatcct tgccacggat gtaaacagca acgatccgat tctttcattt aaaatataac
     7741 gacaaaatat catgaaatac ttaaatctaa tcatactatt attattcctt ctagcttgcc
     7801 aagacaagaa aaaagacgag atcaagcatt tagtatccga atggcaagga aaagagatac
     7861 gatttccgaa agacatggtc tttgcacggt ttgcaaccga tacggtagac ttcaccctgc
     7921 caaaatcccc ccacaaggtg ctggttttcg tggattccat aggatgtacc agttgcaaac
     7981 tccaactgca ccgatggaaa gaactgattc aatacaccga ctccattacc caaggaacgg
     8041 ttcccttcct ctttttcttc cagtccgatg acaagaaaga aatacggtat ctattgaaaa
     8101 aagacaattt cgacaaacct atctgcatgg atcaatcaga cagactgaac gaactgaatc
     8161 atttcccggc cgacgggaga tttcaaacct ttctattgga taaggacaat aaggtcgtag
     8221 tgataggaaa tcctatccac aacccgaata tccgggagct atacctaaaa gagatcaccg
     8281 gaaaacaacc cgcttcacaa atacagacca ccgtgaaagt ggaagaggca tccatacagc
     8341 taggaactat ccaaatggga gaaagcaaag aagctgtttt ccgattaaca aacacaggaa
     8401 acaacccgtt agtcatacta gacgcggcta caacctgcgg ctgtgcccgc ccatctttcg
     8461 acaaacatcc cgccaagccg ggagagatcc ttcaagtaag agtcatcatg acaccgaaag
     8521 acaaaggagt ctttgacgag acgatttccg tgaaatgcaa tacgaatcaa ctgataaaat
     8581 taaacattcg ggggatggct caataaataa aagagaaggg agagcttgcc ggatatattg
     8641 gaacgatcac aagcaagcct cccaccccac ttttactcat gaagcagaaa ggaggtgaca
     8701 caaaagtagt aaattaaatt gaaagaggaa ttcgagaata tccttatctt gcagaagaat
     8761 agtaagcaag agattaaatt ctcaaaaaca taaactataa aaaagaaata tcatgagaaa
     8821 aaagatttta ggaatagccg taatggcagt cgtagcagta gctgcggcat ggaacatcaa
     8881 ccagagtgaa aacgagatta aactctctga tttagcgctt gacaatgtgg aggcattggc
     8941 tagtggggaa ggtggaagcg gatattgcag ttactctggg ggaggatgta ttatcaaata
     9001 ttccgatggg acatccactt acataccggg acgttggaac taaaatttaa tcaaaggagg
     9061 gtgtgccaaa acgaaaaaaa tcacaatgga atacagtcgg taaatcaatg gaatgcagat
     9121 gttttctcat tgatttttaa tttgtatttc atagactcta ggtatcttga gcaagaagaa
     9181 aatgtgttca atcccttaat ttggcatgcc ctccttaaaa aatcagtatc atgaagaaat
     9241 acattatctt acatctttca ctcatcctat tagtattcat cgcttgtacc gatgatcaaa
     9301 aacaagatga caaaaacata accttccaga gaagtgattt caaagtccga aaatcactat
     9361 ccggaaaaac tattgaattt gacagtctta ttttacgacc ttcacaaatc caattattcg
     9421 actccttcct agttacttgc aatcaagggg cggaaaaaca attccacatc ttcaacctca
     9481 atacggcaca taaggaagga gaatgtattc ctgtaggaca agggcctaaa gagatgatga
     9541 caccatgttt cgtcaatcgg aacgattccg tagtcatttt tgatatgatg acctctacga
     9601 ttttcactta ctctatcccg gaatttacca gtggaaaaga accggaatac gccagccgta
     9661 tctccctaga tacaaaaccg ctatggagca atattcgaag cttgggcaac gggttcttag
     9721 gcgtatccta tcaagagacg agtcctggat tcctttttga tcaaacaggt aagaaaacga
     9781 tggatttcgg tacttatcct aaaactgagc aggagtatac tcctgccgaa ttaatcaatg
     9841 cgtttcgggc agacctaacc accaaccgaa aagagaaggt tgcaatcact cactacttca
     9901 ctgatttaat ttgcatctat aacgtgaacg ggaccttgga aaaacaatta cggggaccgg
     9961 atcatttcgc atctgttttc aaagaattta gggatggaga cattatcgga agtaaagcga
    10021 gcccgcaaac ttatagagac gctttttata gtcctgtaaa cgtggggaat agtttatttg
    10081 ttctttataa tggaaaaatg gtgacagagc ctaattacaa tatattatgc aaagaattat
    10141 ttgtaatcgg atgggacggt agccttgaat gccattacac attagaccaa ggagtctcct
    10201 ccatcgctgt agacaatcaa aaacggaaga tctatggtat cagtgatgat ccggaatatc
    10261 atatcgtagt gttcgactat tgatgactga tatccaaaga atttggattt aggaaatgag
    10321 gcataaacat aaaagaatgg gaatagaaaa acgtatatac aaaacaaata taaatcagat
    10381 gttacgatat ctgacactta tattttatgg ggtatttggt attggttgca tatacgcatt
    10441 cctcctcatc ttctgtttca gcacgttcaa aatcccttcc gattccatgg agcctcaact
    10501 ccaaaccgga gatcaagtat tagtaaacaa atggatagcc ggacctaggt tattcaatat
    10561 tttcgcatct atgaaaggga agcgggtaga tatatacaga gtacccggag tcgggcaaat
    10621 caaacggaat gatattctcg tattcaacta cccgcatccc tattcatggg agcggatcga
    10681 aatgcacatc atgcaatatt atatcaaacg ctgcctcggg ttaccgggag actccatccg
    10741 gatcgaacag ggattctacc gaaacaacca tacaaaagag cctttgggga atgtggaaag
    10801 tcaagcgaac ttatccagac aaaaagcgga tcggatgccg gacggtgtct accgttgttt
    10861 cccttttgat tctacattca attggaatgt tcatgatttc ggtcctttgt atatcccccg
    10921 aaaaggggat agaattaccg tgaatcaaac aaattataag ctatacaaac aaatgatcga
    10981 gtgggaatca aaagattccc tatcgtggaa agatagtaaa gtttatatag gagacaaaca
    11041 ggtaagacaa taccagttcc aaagcaacta ttacttcgtg gccggagata agacagaaaa
    11101 ctctagagat tcccgttatc tcggacttat accggaggaa tttatcgtag gggtagcttg
    11161 gaaagtgtgg aaatccgttg acccttacac gggggaatac agaaagggac gtttttggaa
    11221 aaatattcga aacaattgaa gaattatgaa taagcttatt ttatatgtat gcgcttggat
    11281 ctgtctgcac tcttgcggtt tctcaaaaag ccaagaagaa agtatgttgg aatatgcgtt
    11341 gtcgcaagcc ggcgataaca ggaaagagtt ggaatatgtc atcaaatact atgaagggga
    11401 ttcgttaaaa agagaggccg cccgcttttt gatacgcaat atggtctatc atttcggata
    11461 tgagaagcga gagagggtat cagacatcac caccctatcc tcggactatc taatccgtaa
    11521 tatcgagctg gcgtttcagg cgtggcccaa gccctggaat aaatcggtaa gtttcgagaa
    11581 tttttgcagg tatatacttc cctaccgggg gttatacgaa ccgccctccg gtttacgtga
    11641 ggagctgatg cggacgtacc tccctttgct ggatagttcg catattgata acacgtacga
    11701 tgcggccgtg aggttacaaa agatactacg aacccgagtc acctatcaaa cggagatacc
    11761 catccactat ccaaccgcag aggagatcca ccggacaggg gttggacgtt gtgatggggt
    11821 agtcttgtat ggtatccagc tgatgcgtgc ggccggtatt cccactgtag cagaacatac
    11881 gatctggact cgtaggaacg gggaacatta ttggtgcgca ttcttaaacg aggatgggcg
    11941 attcctacct ttcgctccgg agtacgaagg cccggattcc ttgatctaca acctaaccaa
    12001 gccgttcttg accccggcca aggtttacag atacggattc gcccccttac atccggtaac
    12061 gaccgagtcg accgatgaat accgtacgtt cttaaaaaat ccgttattga ccgctgtcac
    12121 ggagcaatac ctaccacctg tcgcagatat ccatacgact tgcgacctcc cggtgagatc
    12181 aaaaagagca cctatttacc tctgtaccta taatcatggt aactggaggc ctttcgccat
    12241 gagcgaacgg atcggcaacc gctgtacctt cccgaagatc gtaggcgatg atgtgtttat
    12301 catcgccgaa tatgacaaag aggcttatgg ctcactacgc ttcatcacat cccctttcca
    12361 tgtgagcaat acggggatca tcacgaaaat taagcccgat ccggcccgaa ccgattccat
    12421 ctttatcgcc tcggacaacc cgtatcaaca gcaagtgccg tatacactcg cttattggga
    12481 acaggaacag cagtgtttta aaaacggata tttcccgaca gacacgatac ccggtggcat
    12541 cctcattcgc aagataccta aagggagcct gttgaaagcg atgatctcgc gaccggaaaa
    12601 ggctgcggaa gatcgtatct ttttggtgga aaacggtacg gtaaaaagat attaaccatg
    12661 aaagaactgt tgaaactcgg cgtatatacc ctacttggga cacttttgct aagcgcccct
    12721 ttcgcaggat tgggaatgct atccacacac ttggtgacag agaaaacctt ttggattcaa
    12781 ctaatcaccc tgttcttatc cgccgtgtcc ctacaaggtt tgtggttgaa tccaagcaag
    12841 gagctgtgcc catggactta cgtggatatc ctcccccttt ccctcttggg gcttatcctc
    12901 ctctcttatc cctactccat acacccggag ccggaaaagc tcctgtttat cggacaaatg
    12961 gttgtcttgt ggtatctgct tcggcaggta ctccatgaat gtccggtgct cataggatat
    13021 ttttcaatgt tctttatcgc gacaggcctt atagaagcca tctggggctt ccgtcaatta
    13081 cagggatggg cctattcgaa ccattccctg tttcggctga ccggctcttt tttcaatccg
    13141 gggccttatt ccggatattt ggcgatcaca ttaccggtgg ctcttggcat cttgctggaa
    13201 cagtccaaac gaaatatgcc ctattacctg tccatgggat gtataggcac agcgatcgtt
    13261 gtacttcctg cgggaatgag ccgatcggca tggatagcgg tggtcgtttc ttgcgcctgg
    13321 gtatatgccc tgtaccgcct tgacaggaaa caggcagcga ccagactgag acaacacaaa
    13381 aggtggtata tcataggcgg tatcctaggc ggcatattgc ttcttggcgg gagcgcatca
    13441 ctctatacat taaagaaaga ttcggcagac ggaaggtttc tgatgtggaa gatcacgacg
    13501 aaagcgatac aaaaacaacc gattacaggt accagcctag gtgggttccc tgccgcttac
    13561 gctgaaacac aagcggaata catggcttcg ggaaaagcga ctgaacagga aaagttggtt
    13621 gccggatgcc cggagtacgc atttaatgaa tacttgcaga ttggattaga acaggggtta
    13681 gtaggattag ccctatttat aggctggctg gggcttctat tttataaagg aataaagaac
    13741 aaaaggtatg cttgttgcgg gggattgatg tctctggcta tattcgcctt ctcttcttat
    13801 ccattacaat tgccggagtt ttgggtagta ttgatattcc taggggtgat gagcgtaaca
    13861 ccggacaagg atgagatccg tgagaaccaa gccgaatcaa atggccatag atggggcaaa
    13921 cagatatttt ttatgggaat cgctatcctt ggaattggtt tgttctggat gcaaaaagat
    13981 cattataagg cttatcaaca atggaacaag gcgcaaatgt attacaaaaa taaagcttac
    14041 gaagcggcct tggaggtata tgaacctttg tatccattat tgaagcataa accggaattc
    14101 cttttcgagg tcgctcaatg cctaagcaag accggacgat acgagaaagc gaatggatat
    14161 ctggaaagag ctgtcttatt aagctccgat cccatgcttt attacgtaat ggctaaaaat
    14221 gagcagtgtt taggtgaata ccgacaagcg gaaaagcacc tgttacatgc cattgatatt
    14281 ttaccggaac gtatctatcc gtattatctg ttaatgaatc tttatacgga accatcttat
    14341 tttcaacctg caaaattgaa aatggcgatt gattccgtat taactaagaa acccaaagtg
    14401 gaaagttccg ctattaaaga aatgaaagag aaagcacgaa gtatgttaaa caacacatca
    14461 atatgaatac aatatcctta tttttatagc aattacgact gcatcgtaac aataaatact
    14521 tatatttgcg aatgacaaat tgtacaaacc gatcaatcat acgagtatga aatactataa
    14581 attgttgacc tttacgcttt tattctgttt aagcgcttgc ggcggagaaa agaaagatac
    14641 agataccaca caggattccg tagaaaccgt attgccggat gaggcgaacg aagtcacgat
    14701 catgactttg aagcaaacgg aatttaatca tgagttgata agcaatggta aactgtccgc
    14761 tcgcaagttg gtggacttac aatttgagtc ggcagaaccc atcgcccgta tctacgtgaa
    14821 gaacggagac cgggtaaaca aaggacagaa aatagcggaa ctcgctactt tccggctcac
    14881 gaacaaaaca gcgcaagcca aggatgccct agagaaagcg aggcttgaat taaaagacgt
    14941 attgatcggt caaggatata tgctggaaga ctcagcgaaa gtcccgcccg cgacgctcaa
    15001 cctagcacgg gtaaaaagtg gatatgatct ggcgctcgcc caatatcaac ttgcccaata
    15061 tgaggaacag aatgcgacgc taatcgcgcc tttcgacggt attatcgcaa accttttcgc
    15121 taaacaagag aacgtggcgt ctacgacgga cgcattctgt accgttatcg atcctcatag
    15181 tctggaagcc tctttcaccg tattggaaag tgagttgccg cttatccaaa acggagataa
    15241 agtggaagtt acccctttcg ccaccaccag cttaaagact gaaggacgta tatccgagat
    15301 caacccgcta gtggatgaga acgggatggt acaagtgaaa gcagcggtaa acgacaaagg
    15361 taaattattc gaaggcatga atgtacgggt tagcgtacaa cgctcgcttg ggaagcaatt
    15421 ggtcgtacct aaaacggctg tggtattacg ttccggaaaa caagtcgtat ttactttagt
    15481 tgatgggcac gcttattgga actacgtgcg caccggactg gaaaacgcgg atagttatac
    15541 ccttttggaa ggattgaaag aagcggatgt cgtgattaca agcggcaata ttaatctggc
    15601 gcatgagtca ccggtcaagg taattaaaaa ttgagaattg agaattgaaa attagttgcg
    15661 tatgattcgc ttcctgctac aacgtccgat agcggtattg atggctttta cggcctgctt
    15721 tatcgtgggg ttggtgactt atttcaccat accggtgtcc ttattgcctg atatcgccat
    15781 acctgagatt accgttcaga tatccgggca aaatacatcc gcacgggaat tggaaaatac
    15841 tgtcgtaaag ccggtccgtt tgcaattgat gcaagtggca ggattacggg atatccatag
    15901 cgagactcgt gatggagcgg gtattatccg ccttagcttc gactttggca cgaatacgga
    15961 tcttgccttt atagaggtca atgagaaaat agacgccgcc atgaattacc taccccgtga
    16021 ggtagaacgt ccacgggtag tcaaggcgag cgctacagac attccagtgt tttgcctcaa
    16081 cctcacactc aagacaattg aaaatgatgc cgctttcctc gatctttgcc aattcgcaga
    16141 aacagtaatc aaacgaagga tcgaacagtt gccggaagtg gcgatggtgg atatcacggg
    16201 catattagga cggcaattac agatcgtacc ggatatgaag ctcttggata tggctgatat
    16261 tacattaaat gatttggaat ctgccttatc cgccaacaat atagagccgg gaagcatgac
    16321 cgtacgggat ggttattatg agtacaatat caaattttcc accttattac gtacaccgga
    16381 agacgtacaa aatatctata tccgtaagaa tgaccggatc ttccagataa aagatctggc
    16441 aaaagtagct gtcgtaccgg aaaaagagac cggcttatcg ctagccaacg ggaaaagggc
    16501 cgttacatta gccgttatca agcaagcgga cgagaatatg gataatatga aagaggcgct
    16561 tgccgaggtt accgattatt tcaa
//
LOCUS       DBMDTB010000087        16501 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_1119_length_16501_cov_12.451585, whole genome shotgun
            sequence.
ACCESSION   DBMDTB010000087 DBMDTB010000000
VERSION     DBMDTB010000087.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 16501)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 16501)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16501
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1119_length_16501_cov_12.451585"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..368)
                     /locus_tag="ACZPB4_12930"
     CDS             complement(<1..368)
                     /locus_tag="ACZPB4_12930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099153.1"
                     /translation="MKKSFLLYLIMSVFLIGYCACDNDEENFDTATTGQVIKVPDDIK
                     SFNSVTKEIVFEKNISIKQDVRGNEKVEFRIAGNGHFTVGSISSISSVIYNAPVLLGD
                     YQRYYLYDGYPVVDVLQNEV"
     gene            complement(553..1320)
                     /gene="lpxA"
                     /locus_tag="ACZPB4_12935"
     CDS             complement(553..1320)
                     /gene="lpxA"
                     /locus_tag="ACZPB4_12935"
                     /EC_number="2.3.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008780 -
                     acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine
                     O-acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP--UDP-N-acetylglucosamine
                     O-acyltransferase"
                     /protein_id="HIR1099154.1"
                     /translation="MISPLAYVDSSAKIGKNVTIHPFAYIDKNVEIGDDCEIMPHASL
                     MSGTRMGNRNRVFNGAVIAAEPQDFFYKGGDTIAVIGDDNVIRENVVINRSSTAEGRT
                     SIGNGNFLHEGVHVSHDTRIGNRSVFGYGSKISGNCILEDYVIFGGNVLMSQGSRVGA
                     WAMIQTGCRFRKDIPPFIVAAQEPTTYYGVNSFIMSHEGFSEKVIKHISHAYRIIFQG
                     NSSLTDALLMIKDQVPMSKEIQHIIDFVGESKLGIVK"
     gene            complement(1344..2735)
                     /locus_tag="ACZPB4_12940"
     CDS             complement(1344..2735)
                     /locus_tag="ACZPB4_12940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008150928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HIR1099155.1"
                     /translation="MTMKKQIIYMVCATALLSSCHIYKAYERPDSIDATGIYRDPVSE
                     TDTLASADTTNMGNLPWKEVFRDPKLQALIEEGLANNVDMQAAVLRVEEAKVLLTSAR
                     LSFLPSINLAPQGTITKMESSGYVKAYTAPAAASWEVDLFGKLLNASRGQKASYLQSQ
                     YSRQAVRSQLIGGIANTYYTLLMLDRQVEITAKTVDIYKENVRVMEAMKMAGMATEAA
                     VTQMRAAYHQVSGSLIELESQVRSVENSLSVLLAKAPQQIDRGTLEEQVMPEDIMVGV
                     PLQLLENRPDVKIAEMTLASAYYTTNKARAAFYPGLNITATAGWTNGSGISVANPGQF
                     MFQALASLAQPIFNNGKLVANLKVSKAEEKIAQMNYQQTILEAGKEVSDALHQYDATS
                     KKLVQDRAQIEQLEKAVAYTSALFQSAQSTYLEILSAQQSLLSAQLTEVSDNVQRMQA
                     VVSLYSAIGGGRE"
     gene            complement(2739..5960)
                     /locus_tag="ACZPB4_12945"
     CDS             complement(2739..5960)
                     /locus_tag="ACZPB4_12945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0042908 - xenobiotic transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HIR1099156.1"
                     /translation="MKLDRFINRPVLSTVISILIVILGFLGLISLPVTQYPDIAPPTV
                     SVRATYTGANAQTVLNSVIAPLEDQINGVENMMYMSSNASNNGSADISIYFKQGTDPD
                     MAAVNVQNRVSMAQGLLPAEVTQIGVTTQKRQNSMLLVFSVYAEDDRYDSEFLENYAK
                     INLIPEVQRVPGVGDANVLGTDYSMRIWLKPDVMAQYKLSPSDVTVALSEQNVEAAPG
                     SFGEQGNQSFQYTIRYKGRLQEANEFEQIVVKALPDGEVLRLKDIADIELGRLTYNFI
                     NRVNGHDAVTCIVYQMPGTNATETISNIETLLEETQLTMPPGMKVNISMNANDFLFAS
                     IHEVIKTLLEAFVLVFIVVYVFLQDLRSTLIPAIAIPVALIGTFFMLSLIGFSINLLT
                     LCAMVLAIAIVVDDAIVVVEGVHAKLDQGYKSAKLASIDAMSELGGAIVSITLVMMSV
                     FIPVSFMGGTAGTFYRQFGLTMAIAIGLSALNALTLSPALCAIFLKPHDEEHKEKKTT
                     FISRFHTSFNAAYDSLLAKYKKQVVFFIQKKWLSFGIVAGCIAVLVFLMQVTPTGMVP
                     NEDTGTIMGAVTLPPGTSQERTYEVMNKVDSLIAADPAVESRTAVVGFSFIGGQGPSY
                     GSFIIKLKDWEDRSMMQNSDIVYGSLFMRAQKIVKDAQVLFFTPPMIPGYSASSDIEL
                     NMQDKTGGNLDRFFDISKEYMAALTARPEIKSAQTTFNPNFPQYEIDIDAAACKKAGI
                     SPKDILSTLQGYYGGLYASNFNRFGKMYRVMVQADPDLRKNMESMKNIKVKSGNDMAP
                     ISQFITMKKVYGPDIISRFNMYTAIKVMVAPADGYTSGQALKAIDEVAKTTLPAGFDY
                     ELGGMAREEASTSGSTTALIFLLCFVFVYLLLSAQYESYILPLSVLLSVPFGLMGSFL
                     FVQGWAALGNIPALKMIVGTMSNNIYMQIALIMLVGLLAKNAILIVEFALERRRMGMS
                     ITWAAVLGAAARLRPILMTSLAMVVGLLPMMFAFGVGAHGNRTLGTAAIGGMFIGMIF
                     QIFIVPVLFVVFQYLQEKFKPIEWEDLDNSDMSTEIEQYAKIK"
     gene            complement(6014..7225)
                     /locus_tag="ACZPB4_12950"
     CDS             complement(6014..7225)
                     /locus_tag="ACZPB4_12950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HIR1099157.1"
                     /translation="MDKRMLKITITQLRQIALFAVGMSLLTACGNSQSGMKLGDAEFA
                     VMAVNSTTSDQTTSYPATIKGTQDIEVRPQVSGFIVKLCVDEGATVRKGQALFQIDPT
                     QYAAAVGQAKAAVEMAKANVSTLTLTEKNKKTLFDQKIISDFEYQTAVNQLMSAKASL
                     AQAEAQLVSANQNLSFCTVTSPSNGVVGTFPYRVGSLVSASIAQPLTTVSEIGDMYVY
                     FSMTEKELLALTKAGGTLKEQLEKMPAVRLQLADGSTYHHEGKIDAVSGVIDQSTGSV
                     SMRAIFSNEGNVLRSGGTGNIIFPYTMNDIITIPQSATVEIQDKKFVFVLQPDNTVKN
                     TEIKVSNLNDGKNYLVTGGLKSGDKIVVEGVQILKDGQEIQPITREQQKAKYDQALKD
                     QHDGNLQTAFN"
     gene            7526..8152
                     /locus_tag="ACZPB4_12955"
     CDS             7526..8152
                     /locus_tag="ACZPB4_12955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099158.1"
                     /translation="MEPKFIISEVFSTAWKGTKSQLWILAGLLIGYCILSFTLTAFAM
                     PMQSSIIGKIIVNVISALFSIIFSLGYMKNIFQALDGEEPQFSAYGQQTKNIITYFLA
                     SLITGFVVLAGFLFFIIPGIYLALRLQFFQAFIIEENAGIIESLHKSWEITKGQVLPL
                     FILALVMIGILILGCILFGIGIFVAVPLIYMMYGYVFRKLNTPLQILE"
     gene            8187..9248
                     /locus_tag="ACZPB4_12960"
     CDS             8187..9248
                     /locus_tag="ACZPB4_12960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011965983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HIR1099159.1"
                     /translation="MNKNYRIKDIAELSGVSTGTVDRILHERGKVSEDARKKVEKVLK
                     EIDYQPNLIARSLALKKKYHFIALIPSFHEGEYWAKLSQGIEKAERELFSYNIDVEQI
                     YFDQYDSNSFDELIPKIETADCQGVIIATLFKQSVLTLTQRLDQKDIPYILIDSFIDH
                     TNCISYYGTHSYDSGYIAGRLLFEQIREEDDLVIFRFTRKGDSCSTQVQKREEGFRDY
                     LANTSFKGKIHLLHVHADDREENTRLLNTFFDKYPQVRIGIIFNSRAHFLGDYLSSER
                     PDYPFKLLGYDVIEPNVRYLENGLITHLIAQRPEVQGYHCIKALFRHLILKEKIEPVN
                     YMPIDILVKENIQYYNNYI"
     gene            9248..10060
                     /locus_tag="ACZPB4_12965"
     CDS             9248..10060
                     /locus_tag="ACZPB4_12965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008643544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HIR1099160.1"
                     /translation="MNSLFSVKEKVILLTGGYGILGACMAKHLAREGAYVVILGRNEQ
                     KGSALVNEIKAEGGEALFLVSNVLDKALLEQNKQEILKAYGKIDVLVNLAGGNQAGAT
                     IPPDKTIFDLDIDAFRTVVDLNLFGTVLPTMVFAEVMVGQGKGSIINISSESSLRPLT
                     RVVGYGCAKAAINNFTQYMAGELAIKFGEGLRVNAMAPGFFLTEQNRALMSNPDGSPS
                     DRCNTIVAHTPFRRLGKPEELLGTLQWLASDASAFVTGTVIPIDGGFDAFSI"
     gene            10135..11313
                     /gene="uxuA"
                     /locus_tag="ACZPB4_12970"
     CDS             10135..11313
                     /gene="uxuA"
                     /locus_tag="ACZPB4_12970"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HIR1099161.1"
                     /translation="MYLCEQTWRWYGPNDPVSLWDIRQAGATGIVNALHHIPNGEVWT
                     TEEIQKRKALIESAGLRWSVVESVPVHEHIKTQTGDFQTYIENYKQSIRNLGACDIRV
                     VTYNFMPVLDWTRTDLAYTMPDGSKALRFERAAFMAFDLFILKRPAAEAEYTEADKAK
                     AKARYDAMSEEDRQLLVRNMIAGLPGSEETFTIEQFREALDRYKDIDAERLRSNLIYF
                     LREIAPVADEAGVKLVIHPDDPPYSILGLPRILSTEDDFRKLIEAVPNPSNGLCLCTG
                     SFGVRSDNDLAGIMERYGDRIDFVHFRSTQRDSEGNFFEANHLEGDVDMYGVMKALLE
                     LQQRRQCSIAMRPDHGHQMIDDLKKKTNPGYSCIGRLRGLAELRGLEMGIALSLFKGH
                     "
     gene            complement(11492..12790)
                     /locus_tag="ACZPB4_12975"
     CDS             complement(11492..12790)
                     /locus_tag="ACZPB4_12975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011965982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0031317 - tripartite ATP-independent
                     periplasmic transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HIR1099162.1"
                     /translation="MDIIGILVLVISFFFLLVVGVPVAYSIGVAGILTMLVNIDSLPA
                     LTTYAMRMASGLDSFALLAIPFFILAGNIMNSGGIALRLIDFAKVLVGRLPGGLAVVN
                     VVANMLFGAISGSAAAAASAIGSIMTPEMKKAGYDPNFSAAVNISSATTGMTIPPSNV
                     LIVYSLASGGVSVSALFMAGYLPGILTGVAIMIVAAMFAARKGYPVGVRVPFSEATRV
                     FFRAIPSLMLLVIVIGGILAGLFTATEASAIAVLYALILSFIYKELTWAKLPQVLLRS
                     AKTTAIVLLLVATCTGLSWIMSYENIPQTVSAALLSISDNPVVILILINVILLIVGIF
                     MDMTPAVLIFTPIFLPIATGQLGMDPVHFGIMMVLNLCVGLCTPPVGSVLFIGCSVAG
                     TKIDQVIRPLLPMFAAMVIVLFLVAFLPDLSLLIPRLFGL"
     gene            complement(12803..13273)
                     /locus_tag="ACZPB4_12980"
     CDS             complement(12803..13273)
                     /locus_tag="ACZPB4_12980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0031317 - tripartite ATP-independent
                     periplasmic transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015740 - C4-dicarboxylate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HIR1099163.1"
                     /translation="MRKIIDKGLELSLIFLMAFLVVDVLWQVLSRYILVSPSSVTDEL
                     AGYLLIWVGLLGAAYVSGKNEHLAIDLLLQHMRPSRRKLLRLFIFLIVFLFAVFVLIV
                     GGAWLVYTRFHLGVTSASLEINLGYVYLALPLGGLLTAYYAIDNAIALFRSSNS"
     gene            complement(13257..14252)
                     /locus_tag="ACZPB4_12985"
     CDS             complement(13257..14252)
                     /locus_tag="ACZPB4_12985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HIR1099164.1"
                     /translation="MKVLKTALLFLMCVSFSFSCKEGVKEVRVLKLAHGLPPSHSVHL
                     GLLYMNERLKELSGGKMSMDIYSSAQLGSENQCIELLQIGSLDITKVSSAALEGFADP
                     FKVFGIPYLFRSREQFFEVLDGSVGKQILGSTEPYWFRGLAYFDSGARSFYTVNKQIR
                     TPEDLKGLKIRVQKSPIAVEMMKTFGGSATPVDWGELYTALQSNVVDGAENNTPSVTT
                     AFHHEVVKYYSVNEHTMCPDVIIISLATWQKLTEQERNWLRQAADAAAIYQRKLWAEQ
                     EKQSLEEMEAHGVEIIYPDKQPFMDAAAPMIERFKNDPVFHDLIDQIQNTHEKDN"
     gene            complement(14502..14804)
                     /locus_tag="ACZPB4_12990"
     CDS             complement(14502..14804)
                     /locus_tag="ACZPB4_12990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HIR1099165.1"
                     /translation="MKEQKEIHIGSLIKEKMEERGLSVSDFAHALHYERTNIYKIFKR
                     SSIDVDLLLRISEVLAYDFLREVYLADEPRRYSITIEADKEDIEEIRKWLLEKRRE"
     gene            15228..16049
                     /locus_tag="ACZPB4_12995"
     CDS             15228..16049
                     /locus_tag="ACZPB4_12995"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M23 family metallopeptidase"
                     /protein_id="HIR1099166.1"
                     /translation="MASKIHNGILILTLILFASCRTQKPAPRPAPPKTMDFPTANIPL
                     PVMDFNFMLPEAPELAVCHSPRKDITEAFTPRDKSQIAIKDPKLFDENNTEIIDLSLI
                     PAGEYAFPLPNGNVISPYGGRRRHHSGVDIKTCANDTIVSAFDGIVRMAKPFAAYGNV
                     IVVRHYNGLETIYSHNSKNLVKPGDRVLAGQPIALTGRTGRATTEHLHFETRINGVHF
                     NPNIVFNMAKRKLRSKCLVCTQKGNNVIVKSVDILPHQKAGPYVPPPPYKWVYNE"
     gene            complement(16090..16489)
                     /gene="ssrA"
                     /locus_tag="ACZPB4_13000"
     tmRNA           complement(16090..16489)
                     /gene="ssrA"
                     /locus_tag="ACZPB4_13000"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
BASE COUNT         4740 a         4114 c         3412 g         4235 t
ORIGIN      
        1 cttacctcat tttgtagaac atctacaaca ggatatccat catataaata atatctctga
       61 taatccccta ataagactgg ggcattatag ataacggaac ttatcgaaga gatactgcct
      121 accgtgaagt gaccgtttcc agctatccgg aattcaacct tctcattgcc tcgcacgtct
      181 tgcttgatag aaatattctt ctcgaaaacg atttcttttg taactgaatt aaaagatttg
      241 atatcatccg ggactttgat cacttgtccg gtagtagccg tatcaaaatt ttcctcatca
      301 ttatcgcaag cgcaataacc gatgagaaat acagacatga taagatataa taaaaatgac
      361 tttttcatat taaacctcct ttattggatt tcattgcgtg ttgtcttatt aataagacac
      421 ttaaaaagag acaaatgctg cacgtttacc attatttaac aaacattatt aaccaaaccg
      481 tccttccatt atataaaaaa agccggagga aatgatttcc ttcggctttt acctatcgtt
      541 tgttattggt atttatttga caatacctaa tttagactca ccaacgaaat ctataatatg
      601 ttggatctcc ttactcatcg gaacctgatc ctttatcatt aacaaggcat ccgtaaggct
      661 gctgtttcct tggaagatga tccggtacgc atgactgatg tgcttgataa ccttttcact
      721 gaatccctca tgagacatga tgaaagagtt cacgccataa tacgtggtag gctcttgagc
      781 cgctacgata aaaggaggta tatccttacg gaaacgacag ccggtttgaa tcatcgccca
      841 agccccaacc cgggatcctt ggctcatcaa tacattgcct ccaaagatca cataatcttc
      901 caagatacaa tttccggaaa tcttactacc atagccgaat acactacggt ttccgatccg
      961 cgtatcatga gaaacatgta ccccctcatg caagaaatta ccattaccga tactagtacg
     1021 tccttccgct gtcgaggaac ggttaatcac cacattctca cgaatcacgt tgtcatctcc
     1081 gattacggcg atcgtatcac ctcccttata aaagaaatcc tgaggctcag cagcgataac
     1141 agctccgtta aatacacggt tgcgatttcc catgcgtgta ccgctcatca agctggcatg
     1201 aggcatgatc tcgcaatcat ccccgatctc cacgttctta tcaatgtacg caaaaggatg
     1261 aatcgtaacg ttcttcccga tctttgcgct tgaatctaca tatgctaatg gactaatcat
     1321 aactttacta catttaaagg ttattattct ctaccaccac cgatggcact gtataaactg
     1381 acaaccgctt gcatacgttg cacattgtcg gatacttccg tcaactgagc gctcaagagg
     1441 ctctgctgtg cggaaaggat ttccaaataa gtagattgag ccgactggaa caaggcgctg
     1501 gtataagcca ccgctttctc tagctgctcg atctgcgctc tatcttggac aagcttcttg
     1561 ctcgtggcat catactgatg taaagcatca ctcacctcct tacctgcttc cagaattgtc
     1621 tgctgataat tcatttgagc gatcttctct tctgccttcg ataccttcaa gttagcgacc
     1681 aacttgccat tgttgaagat cggttgggcc aacgaagcca aagcttgaaa cataaattgg
     1741 cccggattgg cgacagagat gcctgaacca ttcgtccagc ccgctgtcgc cgtgatattc
     1801 aatcccggat aaaaagcggc acgggctttg ttcgtcgtat aataggcact agcaagtgtc
     1861 atctccgcga tcttcacgtc cggacgattc tctaacaatt gcaaaggcac acccaccatg
     1921 atatcctccg gcattacttg ttcctccaaa gtaccccgat caatctgttg aggggcctta
     1981 gccaataaca cggacaatga gttttccacg ctacgcacct ggctctccaa ctcgatcaac
     2041 gagccggaaa cctgatggta agcggcacgc atttgcgtca cggcagcctc ggtagccata
     2101 cccgccatct tcatagcctc catgacacga acgttctctt tatagatatc aaccgtctta
     2161 gcggtaattt ccacctgccg atcaagcatc aacaaggtat aataagtatt cgctatacca
     2221 ccgatcaatt gagagcgcac ggcctgtctt gaatactggc tctgtaagta ggaggctttt
     2281 tggccgcggc tcgcgttcaa gagctttccg aataggtcaa cctcccagct agcggccgct
     2341 ggagccgtgt aagcttttac atacccactg ctttccatct tcgtaatcgt accttgggga
     2401 gcaaggttta tagaaggcaa gaaagacaga cgagcggaag tcagcaatac tttcgcctcc
     2461 tctacccgaa gaacggctgc ctgcatatct acgttattag ctaatccctc ctcaattaac
     2521 gcctgtaact tcggatcacg aaaaacttcc ttccaaggaa ggtttcccat attggtcgta
     2581 tccgcggagg ctaatgtatc agtctcggaa accggatcac gataaattcc cgtcgcatcg
     2641 atggaatccg gacgctcgta tgccttatag atatggcaac tgcttaacaa agcagtcgca
     2701 cataccatat atataatttg tttcttcatt gtcatctctt attttatttt agcgtactgt
     2761 tctatttccg tactcatatc gctgttatcc aaatcttccc attcgatcgg cttgaatttc
     2821 tcctgtaagt actggaatac cacgaacaaa accggaacaa taaagatctg gaagatcata
     2881 ccgatgaaca taccgccgat agccgctgta cccaatgtac ggttaccgtg cgctcctact
     2941 ccaaacgcga acatcatagg caacaatccg accaccatcg ccaatgaggt catcaagatc
     3001 ggacgcaaac gggcggcggc tcctaatacg gcagcccatg tgatactcat acccatacga
     3061 cgacgttcca aagcgaactc tacgatcaag atagcgttct tcgccaacaa acctaccaac
     3121 atgatcaagg cgatctgcat atagatattg ttagacatgg ttcctacgat catcttcaac
     3181 gccgggatat ttcccaaagc ggcccaacct tggacgaaca agaagctacc catcaaaccg
     3241 aacggcacgg agagcaatac ggacaaagga aggatgtaac tctcatactg cgcgctcaac
     3301 agcaagtaaa cgaatacgaa acacaacaag aagatcaaag ccgtcgtact gccactcgta
     3361 cttgcctcct cacgtgccat accacctaac tcatagtcga aacctgccgg aagcgttgtc
     3421 ttagccacct cgtcaatcgc tttcaacgcc tgaccactgg tataaccatc cgccggggca
     3481 accatgacct tgatggcggt atacatattg aaacggctga tgatatccgg gccatatacc
     3541 ttcttcatcg taatgaactg ggaaatcgga gccatatcgt taccgctctt taccttgatg
     3601 ttcttcatgg actccatatt cttacgcaaa tcgggatccg cttgcaccat tacacggtac
     3661 atcttaccga aacggttgaa gttagaggca tataaaccac cataatatcc ctgcaaggta
     3721 gacaagatgt ccttcggact gataccggct ttcttacaag cggcagcgtc gatatcgatc
     3781 tcgtattgcg ggaagttcgg gttaaacgta gtttgagcgg acttgatctc cggacgtgcc
     3841 gtcaaagcgg ccatatattc cttggagata tcaaagaaac gatccaaatt acctccggtc
     3901 ttatcctgca tattcaactc aatatcactg gacgctgagt aaccggggat cataggaggc
     3961 gtaaagaaca atacctgagc gtcctttacg atcttttggg cacgcatgaa caagctacca
     4021 tatacgatat ccgagttctg catcatagaa cggtcttccc agtctttcaa cttgatgata
     4081 aatgagccgt aagaaggtcc ttgaccaccg ataaaactga aaccaacaac cgccgtacgc
     4141 gactctaccg ccggatccgc agcgatcaaa ctatcgacct tattcatcac ctcataggta
     4201 cgctcctggg aagttcccgg tggtaacgta acggcaccca tgatcgtacc cgtatcctcg
     4261 ttcggcacca taccggtagg cgtaacctgc atcaagaata ccaatacggc gatacaaccg
     4321 gcgacaatac cgaatgaaag ccatttcttc tggataaaga acacgacctg cttcttatac
     4381 ttagctagca aagaatcgta agccgcattg aatgaggtat ggaaacggga aataaatgtc
     4441 gttttctttt ctttatgctc ctcatcatgc ggtttcagga atatcgcaca caaggcggga
     4501 ctcaatgtca aggcgttcaa agcggacaaa ccgatagcga tcgccatcgt cagaccgaac
     4561 tggcgataga acgtaccggc cgtacctccc atgaaactta cgggaataaa cacggacatc
     4621 atgaccaacg taatggagac gatagcgcca cccaactcac tcatggcatc gatagaagcg
     4681 agtttcgccg acttgtaccc ttggtccaac ttggcatgga caccctcgac gacgacgatc
     4741 gcatcatcga ccacaatcgc gatggcaagc accatagcac aaagagtcaa caagttgata
     4801 ctaaatccga tcaaggataa cataaagaag gtaccgatca aggcaaccgg aatagcgata
     4861 gccggaatca acgtagaacg caaatcctgc aagaacacat ataccacgat aaacaccaat
     4921 acgaacgcct ccaacaaagt cttgattacc tcatggatag aagcgaacaa gaagtcattg
     4981 gcattcatgg aaatattcac cttcattccg ggaggcattg tcaactgagt ttcctccagc
     5041 aaggtttcaa tgttactaat tgtttccgta gcgttggttc ccggcatctg gtaaacgata
     5101 caggtaacgg cgtcgtgacc atttacacgg ttgataaagt tgtaagtcaa acgccccaac
     5161 tcgatatcgg cgatatcttt caaacgcaag acctcaccat ccggcaaagc ctttacaaca
     5221 atctgctcaa actcattagc ctcttgcaaa cgtcctttat agcggatcgt atattggaaa
     5281 gactgatttc cttgttcgcc gaacgaaccc ggagcggcct ctacgttctg ttcagacaag
     5341 gcaacggtta cgtcgctcgg acttaattta tattgggcca tcacatccgg cttcaaccaa
     5401 atacgcatgg agtagtccgt acccaacacg ttggcatcac cgacacccgg cacacgctgg
     5461 acttccggga tcaagttaat cttcgcgtaa ttctcaagaa actctgagtc ataacgatca
     5521 tcttccgcgt atacggagaa aaccaacaac attgagttct gacgtttctg ggtcgtcaca
     5581 ccaatctgcg ttacctcggc aggcaacaaa ccttgtgcca tagatacacg gttctgcaca
     5641 ttgacagccg ccatatccgg gtccgttcct tgcttaaaat aaatggagat atccgcagaa
     5701 ccattattag aggcattgga actcatatac atcatgttct caacaccatt gatctggtct
     5761 tccaaaggcg cgatcacact attcaatacc gtttgcgcat tggcacccgt ataagttgcc
     5821 cttaccgaaa cggttggagg ggcgatatcc ggatattggg taaccggcaa ggaaatcaag
     5881 cctaggaaac ccaagatgac aatcaagatg gaaatcaccg tggagagcac cgggcggttt
     5941 ataaatctat ctaatttcat atctttcgtt tttactcgac aaaagcgaat atttgtctta
     6001 ttctatatac ctattaatta aaagcagtct gcaaattacc gtcatgctgg tctttcaagg
     6061 cctgatcgta ctttgccttt tgctgctcac gagtaatcgg ctggatttct tggccgtctt
     6121 tcaagatctg tacgccttcc acgacaatct tatcaccgga cttcaaacct cccgtcacta
     6181 aataattttt gccatcattc aaattggaaa ccttgatctc ggtattcttc acggtattat
     6241 caggctgcaa tacaaatacg aatttcttat cctggatctc cacggtagcc gattgaggga
     6301 tcgtaatgat atcgttcatc gtatatggga agataatatt accagtacca ccgcttcgta
     6361 agacatttcc ctcgttagag aaaatagcac gcatgcttac agaaccggta gattgatcga
     6421 taacaccgct cacggcatca atcttaccct catgatggta cgtagagcca tccgccaatt
     6481 gcagtcttac ggccggcatc ttctctaatt gctctttcaa ggtaccaccg gctttcgtca
     6541 atgccaatag ctccttttcc gtcatagaga aatacacata catatcaccg atctcagata
     6601 cggtagtcag cggttgagcg atcgaagcgc ttaccaagct acctacacga tacgggaatg
     6661 taccgacaac accgttcgag ggacttgtaa ccgtacagaa agacaagttc tggttagcgc
     6721 taaccaattg agcctccgcc tgcgccaagc tcgcttttgc cgacatcagc tggttcacgg
     6781 cagtctgata ctcgaaatca ctgatgattt tctgatcaaa caaagttttc ttattcttct
     6841 cggtcaatgt taaagtgctt acgtttgcct tcgccatctc taccgcggcc ttagcctgac
     6901 ctaccgcggc agcgtactgc gtaggatcaa tttggaacaa cgcctgtcct ttacgaaccg
     6961 tagctccctc atccacacat aatttcacga taaatccaga aacttgagga cggacttcga
     7021 tatcctgcgt acctttgatg gtagccggat aggatgttgt ttggtcgcta gtcgttgaat
     7081 tgaccgccat cacagcgaac tcagcatccc ctaatttcat accactctga ctgtttccac
     7141 aggcagttaa taaagacata ccaaccgcaa acaatgcgat ctgccttaac tgagtaatcg
     7201 taattttcag cattcgttta tccatatttg tatataatta tatattcaag gctgtttttc
     7261 agttaccttt tctttctaac ccaagtggag atctttcaca tctattcaca caatagggtc
     7321 tttactcgtc gtttcatcct acaaatgtag aaacttttta cacgatttct gtttcctact
     7381 tatctttttc acctaaatta atagcactta aaaggaagcg cctgttgaaa tacatctctt
     7441 ttggtttcaa acgaaaataa aattgttttt ttcaacaata tattttacat ttgtgtccac
     7501 acacaataaa caaatattat atattatgga gcctaaattt ataatatcag aagtattcag
     7561 taccgcatgg aagggaacga agtcgcagct atggatatta gccggattat taatcggata
     7621 ttgtatctta tctttcacgc tgacagcgtt cgcgatgccc atgcaaagtt ctattatcgg
     7681 taaaatcatc gtaaacgtga tcagcgcgtt attctccatt attttctcct taggatatat
     7741 gaaaaatata tttcaggcgt tggatgggga agaacctcag ttttccgcat atggacaaca
     7801 gacaaagaat atcatcacct actttctagc gagtcttatc acgggatttg tcgtattggc
     7861 gggtttctta ttttttatca tccccggtat ttatctggca ttgcgccttc agttcttcca
     7921 agcctttatt atcgaggaaa acgccgggat tatcgagtct ttgcataaaa gctgggagat
     7981 aacgaaagga caagtattgc ctctgttcat tctggcgttg gttatgatcg ggatcctgat
     8041 attaggatgt attttgttcg gtatcggaat tttcgtcgcc gttcctctta tctatatgat
     8101 gtatggctac gttttccgta aattgaacac tcctcttcaa atactcgaat aaacagagag
     8161 gacgaataca cactacaatc tataccatga ataaaaatta caggataaaa gatatcgccg
     8221 aattatccgg cgtatcaacc ggtacggtag accgcatttt acatgagcgg ggaaaggtat
     8281 cggaggacgc acggaaaaag gtggagaaag tcttaaaaga aattgactat caaccaaatc
     8341 tgatagcccg ttctttagcg ttgaagaaaa aatatcattt catcgctttg atcccttctt
     8401 tccatgaagg ggaatactgg gcgaaactaa gccaagggat cgagaaagcg gaacgggaat
     8461 tgtttagcta taatatagac gtcgagcaaa tctattttga ccaatacgat agcaacagtt
     8521 tcgacgaatt aatcccgaag attgagaccg cggattgcca aggggttatc atcgctacat
     8581 tattcaagca aagtgtcttg accttgaccc agcggctaga ccagaaagat attccttata
     8641 tattaatcga ttcttttatc gaccacacga attgtatctc ttactacgga acgcattcat
     8701 atgattcggg gtatatagcg ggacgccttt tattcgagca aatccgtgaa gaggacgatc
     8761 tagtgatttt ccgtttcacc cgtaaggggg attcatgttc tacgcaagtg cagaagcgag
     8821 aggaaggatt ccgggattat ctcgccaata cctcattcaa gggaaagatt catttgctgc
     8881 atgtgcacgc ggatgaccga gaagagaata cgagactact gaatactttc ttcgacaaat
     8941 atcctcaagt aagaatcggt atcatcttta attcgagggc ccatttcctt ggagattatc
     9001 taagtagcga acggccggac tatcctttca agcttcttgg ctacgacgtg atagaaccga
     9061 acgtccgtta tctggaaaac ggcttgatca cgcatttgat cgcccaacga ccggaggtac
     9121 aaggatatca ttgtatcaag gcactcttca ggcatctgat ccttaaggag aaaattgagc
     9181 ctgtcaatta tatgccgatc gatatcttgg taaaggaaaa tatacaatac tacaataatt
     9241 atatctgatg aactccttat ttagcgtaaa agagaaagtg attttgttga ccggaggcta
     9301 tggtatatta ggagcctgca tggccaagca cttggcgaga gaaggcgcgt acgtcgtaat
     9361 cctcggacga aacgagcaaa aaggatctgc cttggtcaat gaaattaaag cggaaggggg
     9421 cgaggcctta ttcttggttt caaacgtatt ggataaagcc ttgctggagc aaaacaaaca
     9481 agagatattg aaagcatatg ggaagattga tgttttagtc aatttggcgg gtggcaacca
     9541 agccggagcg acgattcctc ccgacaagac gatctttgat ctggatatcg atgctttccg
     9601 gacggtcgtg gacctgaact tattcgggac cgtactgccg acaatggtct tcgccgaggt
     9661 catggtgggg caagggaaag gaagcattat taacatctcg tccgaatcgt ccctacgccc
     9721 attgactcgt gtggttggct atggatgcgc gaaagccgct atcaacaatt tcacgcaata
     9781 catggccggg gagctagcga ttaaattcgg agagggcctg cgagtgaacg ccatggctcc
     9841 gggattcttc cttaccgagc aaaaccgggc attgatgagc aatccggatg gatcacctag
     9901 tgatcgttgc aacacgatcg tcgcgcacac gccgttccgc cgcttaggaa aaccggagga
     9961 gttactcggt accttacaat ggctggcgag cgacgcctcc gcattcgtaa ccggtaccgt
    10021 gatccccata gacggaggtt tcgacgcttt ctccatctaa ataatgtgcc aaccagccat
    10081 gcatcaaacc gcattggcat attggcacat tgataaattt aaaaattatt cattatgtat
    10141 ctatgtgagc aaacttggcg ttggtacgga ccgaatgatc ctgtcagcct ttgggacatc
    10201 cgtcaggcgg gtgccaccgg tatcgtaaat gcgttgcacc atatcccgaa cggggaagtt
    10261 tggactacgg aagagattca aaagcggaaa gccttgatcg aatccgccgg attacggtgg
    10321 agtgtggttg agagtgtgcc cgtacacgag catatcaaga cgcaaaccgg ggattttcaa
    10381 acctatatag agaactacaa acaaagcatc cgtaatctgg gagcttgcga tatccgggta
    10441 gttacttaca acttcatgcc ggtattggac tggactcgta ccgatttggc ttatacgatg
    10501 ccggatggtt ccaaagcctt gcgctttgaa cgcgcggctt ttatggcgtt cgacttattt
    10561 atattgaaac gaccggcggc ggaagccgaa tatacggagg cggacaaggc gaaagccaag
    10621 gcacgctatg acgctatgag cgaggaagac cgccagctgt tggttcgcaa tatgatcgcc
    10681 ggactacccg gctcggaaga gacttttacg atcgagcagt ttagggaagc gttagaccgt
    10741 tataaagata tcgacgcgga gagacttcgc tcgaacctga tctatttctt acgggaaata
    10801 gctcccgtgg cggacgaggc cggtgtcaag ctcgttatcc atccggatga tcccccctat
    10861 tccattctcg ggcttccccg tatcttgagc acggaagatg atttccggaa gttaatagag
    10921 gccgtgccga atcctagcaa cgggctttgc ctatgcacag gttctttcgg tgtcagaagt
    10981 gataacgact tggccgggat catggaacgt tacggggatc ggatcgattt cgttcatttc
    11041 cgcagtacgc aacgagattc cgagggtaat ttcttcgagg cgaaccatct ggagggcgat
    11101 gtggatatgt acggtgtcat gaaagcctta ctggaattgc aacaacgccg ccaatgctcc
    11161 atcgccatgc gaccggatca tggacatcaa atgatagacg acctaaagaa gaaaaccaac
    11221 ccgggctact cctgcatcgg acgtttacgg ggtctggccg agctacgggg attggagatg
    11281 ggtatcgcct tatccctgtt caaaggacat taaaaagaca gcgtcttata gttagcacag
    11341 tactgtgtac gaagtaccgc agtactgtgg ctaaagtact acagtactct gtacgaagta
    11401 ttgcggtact cagtacgtaa gtactggaat acttcgtaca cagtactgcc ctatttatag
    11461 cacaaggcta cctcgaccct atgggggaac atcacaaacc gaacaaccgg ggaatcaata
    11521 aacttaaatc cggcaagaag gccaccaaga acaagacaat aaccatcgcc gcgaacatcg
    11581 gcagcaacgg acggatcacc tgatcgatct ttgtccccgc tacgctacat ccgataaaca
    11641 ataccgaacc caccggtggc gtacataatc ccacacaaag gttcaatacc atcatgatcc
    11701 cgaaatgtac cgggtccatc cccaattgcc ccgtcgctat cggcaggaag atcggggtaa
    11761 agatcaagac agcgggcgtc atgtccataa agatcccgac aatcaatagg atcacgttga
    11821 taagtatcaa gatgaccacc ggattgtcgc ttatacttag caaagcggca cttaccgtct
    11881 gaggaatatt ctcataactc atgatccaag acaaacccgt acaggtcgcc accaaaagaa
    11941 ggacgatagc cgtagtcttg gccgatcgca ataacacttg cggcaattta gcccaagtaa
    12001 gttctttata gataaaagag aggattaacg catacagtac agcgatcgcc gaagcctcgg
    12061 tagccgtaaa caatcccgcc aagattcctc cgatcacgat caccaatagc atcaaactag
    12121 ggatcgccct gaaaaatacc cttgtcgcct ccgagaacgg aacacgtacg ccaaccggat
    12181 acccctttcg tgcggcaaac atagcggcta cgatcatgat cgccactccc gtaagaattc
    12241 ccggtagata accagccata aacaaggcgg atacagagac tccaccactc gccaaggagt
    12301 aaacgatcaa gacattactc ggaggtatcg tcatgccggt agtggcggaa gagatattta
    12361 cggcggcact gaaattcgga tcgtaaccgg cctttttcat ctccggtgtc ataatactcc
    12421 cgatagcaga ggcagcggcg gcggcagagc cactgatcgc cccgaataac atattcgcca
    12481 cgacattgac caccgccagt cctccgggta accgtccgac cagcacttta gcgaaatcga
    12541 tcaagcgcaa ggcgatacct ccgctattca tgatattccc cgccaatata aaaaacggga
    12601 tcgccagcag agcgaaactg tccagacccg aagccatacg catcgcataa gtcgtaaggg
    12661 cgggaagcga gtctatattc acgagcatcg tcaatatacc cgccacaccg atgctatacg
    12721 ctaccggaac cccgaccacc agcaggaaaa agaaacttat cactaatacg agtataccta
    12781 taatatccat atcatcagtc ttttatgaat tagaggaacg aaataaggcg atcgcgttat
    12841 ctatcgcata ataagcggta agcaatcccc ctagcggcaa tgccaaatac acatatccta
    12901 aattaatctc taaggaagcc gaagtaactc ccaaatgaaa acgagtgtat accaaccaag
    12961 cccctcctac gatcaataca aatacagcga ataaaaatac gatcaagaag ataaacaatc
    13021 gcaagagctt cctgcgggaa ggacgcatat gttgaagtaa taaatcgatc gctagatgct
    13081 catttttgcc ggatacataa gcggccccca gcaatcccac ccagatcaat aaatatccag
    13141 ccaattcatc cgtcacggaa ctcggggaaa ccagaatata ccggcttaat acctgccata
    13201 gcacatccac gaccaagaaa gccatcaaga aaatcaacga tagctccaat cctttatcaa
    13261 ttatctttct catgggtatt ctgtatttga tctattaaat catgaaaaac cggatcattc
    13321 ttaaaccgct cgatcatcgg ggcggcggca tccataaacg gctgcttatc cgggtaaata
    13381 atttccactc cgtgcgcttc catctcctct agcgattgct tctcttgctc cgcccaaagt
    13441 ttccgttgat aaatagcggc ggcgtcagcg gcctgtcgca gccaattacg ttcttgttcc
    13501 gtcagcttct gccaagtagc caagctaatg atgatcacgt ccggacacat cgtgtgctca
    13561 ttgactgaat agtattttac cacctcatga tggaatgctg ttgtcacgga aggcgtatta
    13621 ttctcggctc catccacgac attactttgt aaggccgtat acaattcacc ccaatccacg
    13681 ggagtagccg aaccaccgaa tgtcttcatc atctccacgg ctatcgggct cttttgcaca
    13741 cggatcttca gtcctttcag atcctcggga gtacgaatct gcttgtttac cgtataaaag
    13801 ctacgggccc ccgagtcaaa ataagcgagt cccctaaacc aataaggttc cgttgatccc
    13861 aatatctgtt tacctaccga accatccaac acctcgaaaa actgctcacg ggaacggaat
    13921 agataaggta tgccaaatac cttaaacgga tcggcaaatc cttccaacgc agcggaggaa
    13981 actttcgtga tatcgagact tcctatttga agcaactcta tacattgatt ttcggacccc
    14041 aattgagcgg aagaataaat gtccatgctc atctttcctc cggacaactc tttcagacgc
    14101 tcgttcatat agagcaatcc taaatggacg gaatggctgg ggggcaatcc gtgtgccagt
    14161 ttcagcaccc ttacttcctt tactccttcc ttacaggaga aggagaaaga tacgcacatc
    14221 aggaatagca gggcggtctt tagaactttc atattagaaa tgttaacaat tcgttgttta
    14281 tcgacaaata taaaggaaat aatcgaattg tgcacgtaca cagaagaaaa aagtggccgc
    14341 tttcttcctg cctatattca catacggaac aagaagagca cggccttgat ttaacctatt
    14401 tctctaatgt tatgatgaaa catcgagacg gtcaaatgta gaaacaatca aagtgaccgg
    14461 tcttatatcg accgtgatct tatttcacga aagcgtgaaa cttattcacg ccttttctct
    14521 aacagccatt tacggatctc ctctatatct tccttgtccg cttctatagt gattgaatat
    14581 cgccggggtt cgtccgctaa atacacctcc cgcaagaaat cataggctaa gacttccgat
    14641 atacgcagta acaaatcaac atcaatactg cttcgcttaa atatcttata aatattggta
    14701 cgttcataat gaagcgcatg ggcaaaatcg gaaaccgaaa gtccccgctc ttccattttc
    14761 tcttttatta acgaaccgat atgtatctcc ttttgttctt tcatatacaa aagccgtttt
    14821 taaggtaatc ttatctcata aataaaccca catctgagaa aaggtgtgtt acactttacc
    14881 ttaaacccgt caaactgcgg cacgaccaaa tgccttgtac acaacagaaa taaggcaaag
    14941 gaacacacca aatacaggtg tattcgcatt gtctatttct ctgtgtactt taaattggtc
    15001 gttttcagtt tagagaaata ccagcaaata caatatcgtc atcctctctg accaaagagc
    15061 caaactagtc ccctcaatca tcgtataata tctccatttt accttcacaa aggtaggcaa
    15121 attcaactat cagaaaaaac acaaagaata aaaagaagta taaacatatc ggaaatatag
    15181 gtcattgaaa gaggcttttt tatacttttg tggtaaaaca atatctaatg gcatctaaaa
    15241 tacacaatgg aatactcatt cttacgctaa ttttatttgc gtcttgccgt acgcaaaagc
    15301 ctgctccacg cccggcccct cccaagacta tggatttccc tacggcgaat attcctcttc
    15361 ctgtcatgga tttcaatttc atgttgccgg aagctccgga gctagcggtt tgccattctc
    15421 ctagaaaaga tatcacggaa gcctttacgc cccgtgataa aagccagata gcgatcaagg
    15481 accccaagct attcgatgag aataacacgg aaattattga tttatccttg atccccgccg
    15541 gggaatacgc atttcccctt cctaatggaa acgtgatctc tccttacggg ggaaggagaa
    15601 gacatcattc cggagtagat attaagactt gtgccaacga tacgatcgtg tctgctttcg
    15661 atggtattgt cagaatggcg aaaccattcg ccgcctatgg caacgttatc gttgtccgcc
    15721 attataatgg gctggaaacg atctatagcc acaactccaa gaacttggtt aaacccggag
    15781 atcgtgttct cgccggacaa ccgatcgcct taaccggacg taccggcagg gctactaccg
    15841 agcatttaca ttttgagact cgtataaacg gagttcattt caatccgaat atcgtcttca
    15901 acatggctaa aaggaaatta cgttcaaaat gtctggtttg tacccagaaa ggtaataacg
    15961 taatcgtcaa atcggttgat atattacccc atcaaaaggc tggtccatac gtaccgccac
    16021 ctccttataa atgggtttac aatgaatgaa aaaaggtctt acggacaatc cgtaagacct
    16081 tttttcattc cgtggagatg gagagattcg aactctcgtc caaacgagga attaatttgc
    16141 tttctacatg tttatcttcg ccttcattgt cggggaagag caagaccgaa gccacccact
    16201 catcccttat cctctaaagt ttcgcctgag acccgaggct tatctcaaac tatctccgat
    16261 attgctgcac cacctgatcg gaacgcttcg gagccacagc atccgggtga tgtcacgtcc
    16321 ccgcaacttt tgcagggatt aagcttgaat ctactatact tcgattaagc agcgagagcg
    16381 taattatttt cgccagttaa ttgttcgttg tctgagattt aagtgcaagc caaccacgca
    16441 ctacatgctt acaaaccact tctacccgct gtcaaaaccg gtcatcccca tggttttgta
    16501 a
//
LOCUS       DBMDTB010000088        16293 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_1140_length_16293_cov_13.492157, whole genome shotgun
            sequence.
ACCESSION   DBMDTB010000088 DBMDTB010000000
VERSION     DBMDTB010000088.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 16293)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 16293)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16293
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1140_length_16293_cov_13.492157"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..962)
                     /locus_tag="ACZPB4_13005"
     CDS             complement(<1..962)
                     /locus_tag="ACZPB4_13005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010537780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1099167.1"
                     /translation="MNTTNLLKIALRALANNKLRGFLTMLGIIIGVASVITMLAIGQG
                     SKRSIQAQISEMGSNMIMIQPGADMRGGVRQDASAMETLKLQDYEDIVNETRYVSATS
                     PSVNSSGQVIYGANNAPTTVYGISPDYMEIRRYEVEDGDMFSDQDVQTAAKVCVIGKT
                     VVDNLFPGGENPVGKVIRFQKLPFRVVGVLKSKGYNSMGMDQDDLILAPYTTIQKKVL
                     AITHLQGITCSALKEEYTDQAIDEISEILRRNHRLRETDDDDFTIRSMQELSTMLTST
                     TDIMTTLLAAVAGISLLVGGIGIMNIMYVSVTERTREIGLRMSIG"
     gene            complement(1000..1740)
                     /locus_tag="ACZPB4_13010"
     CDS             complement(1000..1740)
                     /locus_tag="ACZPB4_13010"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1099168.1"
                     /translation="MKEIIRLDNIKRDFHVGDETVHALRGVSFTIREGEFVTIMGTSG
                     SGKSTLLNTLGCLDTPTSGEYYLDGVSVRTMNKRQRATLRNRKIGFVFQNYNLLPKTT
                     AVENVELPLMYNPTYKAAQRREKAVNALIAVGLGDRLMHKSNQMSGGQMQRVAIARAL
                     VNDPAVILADEATGNLDTRTSFEILVLFQRLHAEGRTIIFVTHNPEIAQYSSRNITLR
                     DGHVTADTVNTNILSAAEALARLPKNDD"
     gene            complement(1749..2975)
                     /locus_tag="ACZPB4_13015"
     CDS             complement(1749..2975)
                     /locus_tag="ACZPB4_13015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HIR1099169.1"
                     /translation="MDKKKLIMGGVAVILIVGGVFLFTGKSSKGGIKLETAKVGRSTI
                     TNTVTATGTVEPVTEVEVGTQVSGIIDKLYADYNDVVKAGQLIAEMDKINLQAELRSA
                     EAQLASSKTEFEYQQKNYARSKVLHEKQLISDTDYETATYNYEKARAAYDQSQASMVK
                     VNRNLEYATITSPIDGVVINRAVEEGQTVAAGFETPTLFTIAADLTKMQVIADVDEAD
                     IGNVEEGQRVSFTVDAYPNDQFEGVVRQIRLGDSESTSSASSSTSSSTVVTYEVVITA
                     DNPDLKLKPRLTANITIYTLERANILTLPNKALRFIPEPAIMESLGMTVTDPNAEVQP
                     GKRLVWSRQGNTLSPRQITVGTSNNSVTEVTEGLSEGDEVAVDLASAANMPEVGAGAE
                     RSPFMPGPPGSNKNKR"
     gene            complement(3096..4412)
                     /locus_tag="ACZPB4_13020"
     CDS             complement(3096..4412)
                     /locus_tag="ACZPB4_13020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HIR1099170.1"
                     /translation="MKQYALLFACLFFLCVGSKAQEQPTRWTLRACLDYALEHNIQVK
                     KSKVSHLSGIEDTKQAKAQLFPSLSASVTQGFVNYPSSDAATNNSYSGNYALNAKWTL
                     FDGGQRVQAIKQQEIQNTVDELGIEQNEDDIQISLIQTYMQVLYAMESVRINQNTVEV
                     STAQRDRAVELLRAGSISKVDLAQLESQLSTDKYQLVVAQTNLDNYKLQLKQLLELDI
                     TEEIELVMPELTEKDILTPLPSKQTIYNTSLAVMPQIKSSELAVDIAELEKKKAKGAF
                     LPSLSMNAGLGTGHLSGTDYAFGSQVWNSFNESVGLTISIPIFSNRQYKTAYNKAKYA
                     ITTSQLELLNTQKQLLQTVEGIYLDATSSQTQYISATERLSYVKESYNLIDEQFSLGM
                     KNTLELLTEKNNYLTAQQEQLQAKYMALMSVQLLNVYQKKPVAENY"
     gene            complement(4535..5086)
                     /locus_tag="ACZPB4_13025"
     CDS             complement(4535..5086)
                     /locus_tag="ACZPB4_13025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015109 - chromate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015703 - chromate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HIR1099171.1"
                     /translation="MIWLQLLYVYLKIGILGFGGGYAMLSLIQADVVDRYGWISLQEF
                     TDIVAISQMTPGPIGINSATYIGYTAVHNAGYSETMSILGSCLTTFAVCLPSFLLVLL
                     ISYFFAKFRNNKYVEAAFLGLRPATVGLIAAAALLLMNKENFIDYKSFLIFGAAFILT
                     WKFKVHPILMIILAGIAGIILYW"
     gene            complement(5088..5615)
                     /locus_tag="ACZPB4_13030"
     CDS             complement(5088..5615)
                     /locus_tag="ACZPB4_13030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015109 - chromate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015703 - chromate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HIR1099172.1"
                     /translation="MYWTLFLTFVKIGMFTIGGGYAMLPLIQRDVVDRGWMTKEDFID
                     VFSVAQSLPGIFAVNIAIFVGYKLKKTWGGFVCALGTILPSFVIMLLIALFFTQVKDN
                     VWVEKAFMGLRPAVVALIAVPCLTTARSIKLSYVQMIIPVGAALLIWMGGVSPAWIIL
                     AAIAGGLVYGLNKKG"
     gene            complement(5637..7226)
                     /locus_tag="ACZPB4_13035"
     CDS             complement(5637..7226)
                     /locus_tag="ACZPB4_13035"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S41 family peptidase"
                     /protein_id="HIR1099173.1"
                     /translation="MKRIVLSLLIVLGVFTGATAQKANMDARKLQLALFAISNLYVDS
                     TSETKLVEDAIVGMLDKLDPHSNYMDPEETKEMTEPLQGNFDGIGIQFNMLTDTLYVI
                     QVIPGGPSEKVGLMAGDRIIQVDDTLIAGVKMKTTDIMKKLRGPKGTEVRVKVKRGKS
                     PELMDFKIVRGKIPVYSLDAAYMADKNTGYIKLNRFAASSADEFREALEKLRKQGMKN
                     LILDLQGNGGGYLNIAIELADEFLDKNRLIVYTKGSKQPREEANSTARGQFQEGRLVV
                     LVDESSASASEIVSGAIQDWDRGVIVGRRTFGKGLVQKPIPLPDGSMIRLTVSRYYTP
                     TGRCIQKPYENGKMEEYHHDLIDRYNRGELMSADSIHFPDSMRYNTLVTERTVYGGGG
                     IMPDVFIPVDTARYTDYHRKLVASGLVNRVSMNYLDRNRNQMMAKYPKFQQYKQGFVV
                     GEDIMEELLKMAGDEKIEFEEEQYNRSKPLIMLQIKALIARDLYDMAQYFQIINDDNP
                     SYQKALQIINNKETYNRLLGR"
     gene            complement(7250..7723)
                     /gene="coaD"
                     /locus_tag="ACZPB4_13040"
     CDS             complement(7250..7723)
                     /gene="coaD"
                     /locus_tag="ACZPB4_13040"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HIR1099174.1"
                     /translation="MSSIENKRIALFPGTFDPFTIGHQSLVRRGLELVDEIVISIGIN
                     DKKLTYFSLEKRMEAIWNLYKDNPRVKVMSYNQLTVDFAKEVGAGFILRGIRTVNDFE
                     YEKTIADVNRKLTGIETFILFTEPEHTHISSSIVRELLRYGKDISQFVPKETRLY"
     gene            complement(7710..9575)
                     /locus_tag="ACZPB4_13045"
     CDS             complement(7710..9575)
                     /locus_tag="ACZPB4_13045"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HIR1099175.1"
                     /translation="MDELNSTIQQPTEYNDDDIKTLDWMEHIRRRPGMYIGKLGDGSY
                     ADDGIYVLLKEVLDNSIDEYMMGYGKSIEVTIEEGTVAVRDYGRGVPLGKVVDVSSKM
                     NTGAKYDSKAFKKSVGLNGVGIKAVNALSSYFLITSYRDGECKRVEYSKAIVTEESDI
                     QPTGEANGTQVFFVPDREIFKDYHYKDEFIEGLLKNYVFLNSGLSIIYNGKRFYSRNG
                     LVDLLNENMTTEPLYPIIHLKGEDIEVVITHSNQYGEEYYSFVNGQHTTQGGTHLSAF
                     KESIGRVIKEYYNKNFEYSDIRAGIVAAISIKVEEPVFESQTKTKLGSKDIGPDGPTV
                     AKFIGDFIKNDLDNYLHKNMETSELLLKKILESEKERKAIAGVTKLARERAKKANLHN
                     KKLRDCRIHLTDSKGDLLEESSIFITEGDSASGSITKSRNPNYQAVFSLRGKPLNSYG
                     LTKKIVYENEEFNLLQAALNIEDGLEGLRYNKVIIATDADVDGMHIRLLLITFFLQFF
                     PDLIKRNHVYILQTPLFRVRNRQKTWYCYSEEERLAAIAAAGKNPEITRFKGLGEISP
                     DEFKHFIGKDIRLDPVTMKKEDLVKDMLEFYMGKNTMERQNFIIDNLVVEEDVIN"
     gene            complement(9581..10708)
                     /locus_tag="ACZPB4_13050"
     CDS             complement(9581..10708)
                     /locus_tag="ACZPB4_13050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099176.1"
                     /translation="MSVEIREVTSKKELKKFVKFNIELYKGNPYHVPGLIEEEMMTLD
                     KKKNPAFEVCDAIYFLAYKDGKVVGRIAGMVNRPSNEAWGQKRARFGFVDFIDDDEVV
                     DALFGAVEKWAREQGMEEIHGPMGFTDMDHEGMLIEGFDQIGTMATIYNYPYYPKQVE
                     RIGYGKDQDWHEFKIYIPDGVPEKHLRIGEIVKKKYGLKVLKFKNAKEIMPYARPVFH
                     TLNAAFAPLYGFAQLTEKQIDYYINMYIPMLRYDLVTLIVREEDNAVVGFGISLPNLS
                     RALQKARGHMLPFGWIHLLKALKSKPKVIDLYLTGVLPEYQSKGVNALLFNDLIPVYK
                     RIGAVYAESNPELETNSAVQAQWDYFKREHHKSRRAYIKKL"
     gene            10847..11755
                     /locus_tag="ACZPB4_13055"
     CDS             10847..11755
                     /locus_tag="ACZPB4_13055"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMP-30/gluconolactonase/LRE family protein"
                     /protein_id="HIR1099177.1"
                     /translation="MFEGTSCINDPIIISPDLAFRAEATTGEGSIWHPDRNTLFWVDI
                     EGKTLYEYIPDLQNCRSWQFDRMVSTVVPETDSTVVVALQNEIIRVNLTDGNTTSIAP
                     IPDNNGKIRCNDGKCDPSGRLWIGTMGFGAPKGAASLYCVWADGTVETKLTKVTISNG
                     IVWSANKKYMYYNDTPTRKIIRFRYDDSSGDILYDGVAVNIPEGTGSPDGMTIDCNDN
                     LWVAQWGGGGVYCYNPYTGDLLTKIVVPAPHVASCAFGGDKLDTLYITTARAGLSEEQ
                     LEEYPLSGSVFCCKPGAKGVPANCFH"
     gene            11894..14080
                     /gene="rnr"
                     /locus_tag="ACZPB4_13060"
     CDS             11894..14080
                     /gene="rnr"
                     /locus_tag="ACZPB4_13060"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HIR1099178.1"
                     /translation="MAKNRPAKKDNNKEKKGKKDKGVGKRMKKEAMIQAIISVFQSSP
                     KEPFNYKQISKIIGVENQVQKLQVVDILYDLSAEDIITEIDRGRYRLNGLGTLAVGTF
                     ARRSNGKNSFIPEDGGTPVFIAERNSGHAMDGDKVKVQLFAKRKGAEPEGEVVEILES
                     KERTFVGKLQVAKGFAFLITENKTLANDIFIPKDKLKGGKNGDKAIVRIVEWPDEAKN
                     PLGEVIDILGIAGQNTAEMHAILAEFGLPYKYPSSVEKAADKIPEAISPEEIENREDF
                     RGITTFTIDPKDAKDFDDALSARRLDNGNWEVGVHIADVTHYVKTDGVIDKEAQSRAT
                     SVYLVDRTIPMLPERLCNQICSLRPDEEKLCFSAVFELNSDAVVQNSRICRTIIKSDR
                     RFTYEEAQEVIETGEGDYKEEILALNDLAKKLRERRFKSGAINFDRYEVKFEIDEQGK
                     PVRVYFKVSKDANKLIEEFMLLANRTVAEFVGRPPKGKTKKTFVYRIHELPDPDKMEN
                     FASFIRRFGYKLKTDGTKTDVSKGINSLLDNVQGKPEENLIETVAIRAMQKARYSTEN
                     IGHYGLAFEYYTHFTSPIRRYPDMMVHRLLERYLAGGRSVIQKKYEDLCDHCSSMEQV
                     AANAERASIKYKQVEFMQDKLGMVFDGVISGVTEWGLYVELNENKCEGLVPIRDLDDD
                     YYEFDEKNYCLLGRRKKRQYRLGDPITIKVAQANLERKQLDFQLAE"
     gene            complement(14184..14396)
                     /locus_tag="ACZPB4_13065"
     CDS             complement(14184..14396)
                     /locus_tag="ACZPB4_13065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity 17 family protein"
                     /protein_id="HIR1099179.1"
                     /translation="MDPSEYFILSLFIALGLFSIVAAICNFDWYFKTSGAMTFVNWFG
                     RGGARIFYALLGIGLIACGALGLMYW"
     gene            complement(14401..14820)
                     /gene="tsaE"
                     /locus_tag="ACZPB4_13070"
     CDS             complement(14401..14820)
                     /gene="tsaE"
                     /locus_tag="ACZPB4_13070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HIR1099180.1"
                     /translation="MSTLKIESLDKIHEAAKEFIAGMDDRTVFAFYGPMGAGKTTFIK
                     AICEELGVEDVINSPTFAIINEYRSDTTGELIYHFDFYRINKLSEAEDIGTEDYFYSG
                     ALCFIEWPEKIDELLPGDVVNVTISENPDGSRTVEVK"
     gene            complement(14896..>16293)
                     /gene="porX"
                     /locus_tag="ACZPB4_13075"
     CDS             complement(14896..>16293)
                     /gene="porX"
                     /locus_tag="ACZPB4_13075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009016776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="T9SS response regulator signal transducer PorX"
                     /protein_id="HIR1099181.1"
                     /translation="IIFLDENMPGLTGLETLSHIKEIAPNVPVVMVTKSEEESIMNQA
                     IGNKIADYLIKPVNPNQLLLSIKKNVHKNVIISETTTVGYQQEFGRIGMQINDSLTTD
                     DWMEVYKKLVYWELELESSQVAMTDMLRMQKEEANNAFAKFVKKNYVDWIQNPADRPL
                     MSPDLFKKKVFPMLDNDEKVFFILIDNFRLDQWRVVKELLTEYFTFDESLYYSILPTA
                     TQYARNSIFSGLMPSQIEQMFPDLWVDEESEEGKNLNEAPLIQTQIDRFRKKYTFSYN
                     KVHDSQYGEKLLATIPSLTRNQLNVIVLNFVDMLSHARTESKMIRELAQSEAAYRSLT
                     KSWFQHSSTLELFKRIAERGGKVIVTTDHGTIRVTNPIKVIGDKNTNTNLRYKVGKNL
                     NYNPKEVFEIRDPEKVGLPSPNLSSKYIFAYGENFFAYPNNYNYYVSYYKNTFQHGGI
                     SMEEMLVPFITMEPK"
BASE COUNT         4269 a         4252 c         3498 g         4274 t
ORIGIN      
        1 ccgatactca tacggaggcc gatctcccgc gtacgctccg tcacgctcac gtacatgata
       61 ttcatgatac cgataccacc aacgagaaga gagataccag ccaccgcggc cagcaacgtc
      121 gtcattatat ccgtcgtact tgtcaacatc gtgctcaact cctgcatact ccggatcgtg
      181 aaatcatcat catcggtttc ccgcagccta tggttacgcc tcagtatctc cgatatctcg
      241 tctatggcct gatcggtgta ctcctccttg agcgccgagc aggttatacc ttgcaaatgg
      301 gtaatggcca agaccttttt ttgaatagtt gtgtatggag ctaagatcag gtcgtcttgg
      361 tccattccca tgctattgta tcctttgctt ttcagtacgc ccacgacccg gaacggtagc
      421 ttctggaaac ggatcacctt accgacggga ttctctccgc cggggaaaag gttatccacc
      481 accgtcttcc cgatcacgca taccttggcg gcggtctgca cgtcctgatc gctgaacata
      541 tcgccatcct ccacctcgta tcggcgtatc tccatataat ccgggctgat accgtagacg
      601 gtggtcgggg cattgttggc gccatagatg acctgcccgc tactgttcac ggagggcgaa
      661 gtggcggaga cgtagcgagt ctcgttcacg atatcctcgt agtcctgtag cttcagcgtc
      721 tccatggcag aggcgtcttg gcggacacca ccacgcatgt cggctcccgg ctggatcatg
      781 atcatgttcg agcccatctc gctgatctgc gcctgtatac tccgcttcga gccttgacca
      841 atggccagca tcgtgatcac ggaagccacg ccgatgatga tacccagcat tgtgaggaat
      901 ccccgcagct tgttattggc caaggcccgg agggctatct ttagtaaatt cgtcgtattc
      961 attctaaata atatgctatt accacattaa ttcattattc taatcatcat tcttgggcag
     1021 gcgggccaaa gcctcggcgg cgctcaagat attcgtattc accgtatcgg cggttacatg
     1081 accgtcgcgc aacgtgatat tccggctgct gtattgggcg atctccgggt tgtgggtgac
     1141 gaagataatc gtgcgtccct cggcgtgcag gcgctggaag agcaccaaga tctcgaaaga
     1201 ggtacgggta tccaagttgc cggtagcctc atccgcaagg atcaccgccg gatcgttcac
     1261 caaggcacgg gcgatcgcca cacgctgcat ctggccaccg gacatctggt tacttttatg
     1321 catcagtcgg tctcccaagc ccacggcgat caaggcgttg accgccttct ccctacgttg
     1381 ggccgcttta taagtaggat tgtacatgag aggaagctct acgttctcta ccgctgtcgt
     1441 cttcggcaac agattgtaat tttgaaaaac gaatccgatc ttgcgattcc ggagggtcgc
     1501 tcgctgccgc ttgttcatgg tgcgcacgga tactccgtct aagtaatact ccccgctcgt
     1561 aggagtatca aggcaaccca gcgtgttcag caacgtactc tttccggagc cggaggttcc
     1621 catgatcgta acgaactccc cctcgcgaat cgtgaacgac acgcctcgca gggcatggac
     1681 ggtctcgtcg ccaacgtgga agtctcgttt tatattgtct aatctgataa tttctttcat
     1741 gacgcaaact atctcttatt tttgttgctt cccggagggc ccggcatgaa ggggctacgc
     1801 tccgctcctg cacctacttc cggcatgttg gcggcgctcg ctaaatctac ggctacctca
     1861 tcgccctcgc tcaagccctc ggttacttcg gtcacgctgt tgttgctggt tccgaccgta
     1921 atctgcctcg ggctcaaggt atttccttgg cgggaccaaa ccaagcgttt tccgggttgt
     1981 acctccgcat tcggatccgt cacggtcata cccaacgatt ccatgatggc gggctcgggg
     2041 ataaaacgaa gtgccttgtt cggcaaggtc aggatattcg cacgttccaa cgtataaatc
     2101 gtgatattcg ccgtcaagcg aggtttcagt ttcaagtccg gattatctgc cgtaatcact
     2161 acctcgtagg taacgaccgt agaagaagaa gtactggaag aagcgctgga ggtgctttcg
     2221 ctatccccaa ggcgaatctg gcgaaccacg ccctcgaatt gatcgttcgg ataggcatcc
     2281 accgtaaaac taacccgttg gccttcctcc acattaccta tatccgcctc atccacatcc
     2341 gctattacct gcatcttcgt caagtcggcg gcaatggtaa acagcgtcgg ggtctcgaag
     2401 ccggcggcaa cggtctgccc ttcctcaacg gcccggttga taaccactcc gtctataggg
     2461 ctcgtgatcg tggcatattc gagattacgg tttaccttta ccatggaggc ctgactctgg
     2521 tcgtaagcgg ccctcgcctt ctcgtaatta taggtagccg tctcataatc cgtatcgcta
     2581 atcaattgtt tctcgtgaag caccttgcta cgtgcgtagt tcttctgttg atactcgaac
     2641 tccgtcttgc tgctcgccaa ttgcgcctcg gcggaacgaa gctcggcttg gaggttgatc
     2701 ttatccatct cggcgatcag ttggccggct ttcaccacgt cgttataatc agcgtacaac
     2761 ttatcgatga taccggagac ctgcgtacct acctcaacct cggtaacggg ctctaccgta
     2821 ccggtggccg taaccgtatt cgtgatcgtg ctgcgcccta ctttagcggt ctccagcttg
     2881 attccgcctt tcgaggattt gcccgtgaaa aggaacacgc cccccacaat gaggataacg
     2941 gcaacaccgc ccatgattag tttcttcttg tccatattct gattcgtttt atttctgttt
     3001 tacgttgtat tcttgttcaa aaggcccccg cgacctccgt cgcagggtaa ccttgaaaaa
     3061 agagagtgga gtaaatatat atatccatta gtgggttaat aattctccgc aaccggcttc
     3121 ttctgataaa cattcagcaa ttgaacgctc atcaaggcca tgtatttcgc ttgtagctgc
     3181 tcttgctggg cggtcagata attgttcttc tccgtcaata gctcaagcgt atttttcata
     3241 ccgaggctga attgctcatc gatcaagtta tagctttctt tcacgtaact caagcgttcg
     3301 gtagccgaga tatattgggt ctgcgacgag gtagcgtcca gatagatccc ctccacggtt
     3361 tgcagcaatt gtttttgggt attcagcaac tccaactggc tggtggtaat cgcgtatttc
     3421 gccttgttat aggccgtctt atactgacgg ttactgaaga tagggatgct gatcgtcaat
     3481 ccgacactct cgttgaaact attccagacc tggctaccga aagcgtaatc cgttccggaa
     3541 agatggccgg tacccagccc ggcgttcatg gagagcgaag gaaggaaagc acctttcgcc
     3601 tttttcttct ccagctcggc gatgtccacg gccagctcac tgctctttat ttgcggcatc
     3661 acagccagag aggtattgta aatcgtttgc ttgctcggaa gcggggttaa gatatctttc
     3721 tccgtaagct ccggcatcac caattcgatc tcttcggtta tatccagttc tagtaattgc
     3781 ttcaattgca acttataatt gtctagattc gtctgggcta cgaccaattg atatttatcg
     3841 gtgcttaact ggctttccaa ctgagccaaa tccactttcg agatcgaacc ggcacgtagc
     3901 aactccaccg cacgatcccg ttgcgccgta gatacctcga ccgtattttg gttgatacga
     3961 acggactcca tcgcatatag tacctgcata taggtctgta tcaaggagat ttggatatca
     4021 tcctcgtttt gctcgatacc cagctcatcg acggtatttt gtatttcctg ttgcttgatc
     4081 gcctgtacac gttgccctcc atcaaaaagc gtccatttag cgttcagcgc ataattaccg
     4141 ctatagctat tattcgtagc ggcgtcgctc gaaggataat tcacgaatcc ttgggtaacc
     4201 gaagccgaaa gggaagggaa aagctgtgct ttcgcctgct tcgtatcctc tataccggaa
     4261 agatgcgaca ccttgctttt ctttacttgg atattatgct ccaaagcgta atccaagcaa
     4321 gcgcgcaacg tccatcgggt aggttgctct tgtgccttac tccctacaca gaggaagaac
     4381 agacatgcga ataataaagc gtattgtttc atattgcctt cgttttctat ctttttacga
     4441 aagcaaaact atattacctt aaaaacatgg gcaaccagac tagaaaaagg ggctgttttc
     4501 accgattaaa cgggcaattc catcgacatc gggattacca atataaaata atacccgcga
     4561 tacccgccaa gatgatcatc aagataggat gtaccttgaa tttccatgtt aggatgaaag
     4621 cggcaccaaa gatcaagaag ctcttgtagt cgatgaagtt ctctttattc attaatagca
     4681 aggcagcggc agcgatcagt cccaccgtag ccgggcgtaa tccaaggaaa gccgcctcta
     4741 catatttatt attccgaaac ttagcgaaga aataagagat cagaaggacc aataagaaag
     4801 aaggcagaca taccgcaaat gtcgtcaggc aagatcctag gatactcatc gtctccgaat
     4861 accccgcatt atgcaccgcc gtatacccta tataggtggc gctattgata ccgatcggtc
     4921 cgggtgtcat ttgagagata gcgacaatat cggtaaactc ctgcaaggaa atccaaccat
     4981 agcggtccac cacgtcggct tgtatcaagg ataacatcgc atacccacca ccaaagccca
     5041 atataccgat cttcagatat acatataata attgtaacca aatcatatca gcccttctta
     5101 tttaaaccat acaccaaacc tccggctata gccgccaaga taatccaagc gggagacacc
     5161 ccacccatcc agatcagcaa tgccgccccg acaggtatga tcatttgcac gtaactcaac
     5221 ttgatagaac gtgcggttgt cagacaaggc acggcgatca aggcgaccac cgccggacgc
     5281 aatcccataa acgccttctc cacccataca ttatccttta cctgcgtaaa gaataacgcg
     5341 atcaagagca tgattacaaa agaagggaga atcgtgccca aggcacaaac aaaaccgccc
     5401 catgtcttct tcagtttata acccacgaag atcgctatat tcacggcgaa aatacccggc
     5461 aacgattggg ccacggagaa aacgtcgata aagtcctctt tcgtcatcca cccccggtct
     5521 accacatccc gctggataag cggcaacatg gcgtaaccac ctccgatggt aaacataccg
     5581 attttcacga atgtcagaaa aagcgtccaa tacataccct tatcagttta cgttggctaa
     5641 cgtcctaaaa gcctattgta agtttcttta ttattaataa tctgaagcgc tttctggtaa
     5701 cttggattat catcattgat aatctggaag tactgcgcca tatcatagag atcccgtgcg
     5761 ataagcgcct tgatctgaag catgatcaac ggcttcgaac gattatattg ctcttcctca
     5821 aactcaatct tctcatcgcc ggccatctta agaagctcct ccatgatatc ctctccgacc
     5881 acgaaacctt gcttatactg ctggaatttc ggatatttag ccatcatctg gttccgatta
     5941 cgatccagat aattcatgga cacccgattg accaaaccgg aagctaccag tttccggtga
     6001 taatccgtat agcgagccgt atctaccggg atgaacacgt ccggcataat acctccaccc
     6061 ccatatacgg tacgctcggt aaccaaggtg ttatacctca ttgaatccgg gaaatgaatg
     6121 ctatcggcac tcatcaactc cccccggtta taacggtcga tcagatcatg gtggtactcc
     6181 tccatcttcc cgttctcgta aggcttttgt atacaacgtc cggtgggtgt atagtaacgg
     6241 gaaaccgtca aacgaatcat ggaaccatcc ggcaggggaa tcggtttctg taccaaacct
     6301 ttgccaaagg tacggcgacc tacgatcact ccacggtccc aatcttgaat agcgccggag
     6361 acgatctcgc tggccgaagc cgaggactcg tccaccagca cgaccaaacg tccctcttgg
     6421 aattgtccac gagcggtaga gttcgcctcc tcacgaggtt gcttactccc tttcgtataa
     6481 acgatcaacc ggtttttatc caagaactca tccgctaact ctatggcgat attcaaatat
     6541 cccccaccat ttccctgcaa atccagaatc aagttcttca tgccctgttt ccggagcttc
     6601 tccaacgcct ccctgaattc atcggcggaa gaagcggcga aacggttcaa cttaatataa
     6661 ccggtattct tatccgccat ataagcggca tccagactat acacgggaat cttaccgcga
     6721 acgatcttga aatccatcaa ttccggcgac ttgcctcgct ttactttcac acgcacctcg
     6781 gtacctttcg gtccgcgtag tttcttcatg atatcggtag tcttcatctt cacgccggcg
     6841 atcaaggtat cgtctacttg gataatacgg tcgcccgcca tcaaccccac cttctcagag
     6901 ggacctccgg ggattacctg aatcacgtaa agcgtatccg tcaacatatt gaactgtatg
     6961 ccgataccat cgaaattgcc ttgtaaaggc tcggtcatct ctttcgtctc ctccgggtcc
     7021 atataattgg aatgagggtc tagcttatcc aacatgccga ctatagcgtc ttccaccaac
     7081 ttcgtctcgc tagtagagtc gacatataga ttagatatag cgaataaagc caattggagc
     7141 ttccgggcat ccatattcgc tttttgcgct gtcgctccgg taaacacacc taggacgatc
     7201 agcagggata agacgattct tttcatcaga tatattcgtt tcataatttt caatacaatc
     7261 tcgtctcttt agggacgaat tgggaaatgt ctttgccgta gcgtaacaac tcacggacaa
     7321 tgcttgagct aatatgcgta tgctccggtt ccgtaaacaa gataaaagtc tcgatacccg
     7381 tcaacttacg attcacgtcc gcgatcgtct tctcatattc gaaatcattg accgtacgga
     7441 ttcctcttaa gataaagccg gctccgacct ctttagcgaa atccaccgtc aattgattat
     7501 atgacatgac tttcaccctt ggattatcct tgtatagatt ccagatcgct tccatccgct
     7561 tctccaagga gaaataggta agcttcttat cgttgatacc gatcgagatc acgatctcgt
     7621 ccaccagttc caacccacgc cttaccaagg attgatgccc gatcgtaaaa ggatcgaagg
     7681 taccgggaaa aagcgcgata cgtttatttt caattgatga catcttcttc aaccactaag
     7741 ttatcgataa taaagttctg tcgctccatg gtattcttcc ccatatagaa ctcgagcata
     7801 tctttcacga ggtcctcttt cttcattgtc accggatcaa ggcgtatatc cttgccgata
     7861 aaatgcttga actcatcggg agagatctct cccagacctt tgaatcgggt gatctccgga
     7921 ttcttcccgg cagcggctat ggcagccaag cgttcctcct ctgaataaca ataccacgtc
     7981 ttctgccggt tacgtacccg gaataacggg gtttgcaaga tataaacatg attacgctta
     8041 atcaaatcgg ggaagaattg caagaagaag gtaatcaaca ataaacggat atgcatcccg
     8101 tccacgtcgg catctgtcgc gataatcacc ttattatacc gcaaaccttc caagccatcc
     8161 tcaatattca aggccgcttg aagcaagtta aactcctcgt tctcgtaaac gatcttcttt
     8221 gtcaagccat aactattcaa aggcttaccc ctcaaactaa atacagcttg gtaattcggg
     8281 ttacggctct tcgtgataga accgctagcc gagtcaccct ccgtgataaa gatactgctt
     8341 tcctctagca aatccccttt cgagtcggtc aggtgaatcc ggcaatccct tagtttctta
     8401 ttatgtaaat tcgctttctt cgcacgctcg cgggccagct tcgtaacacc ggcgatcgcc
     8461 ttgcgctctt tctcggactc caagatcttc ttcagcaaaa gctccgaagt ctccatattc
     8521 ttatgcaaat agttatccag gtcattcttg atgaaatcac cgataaactt cgctaccgta
     8581 gggccgtccg gtcctatatc cttcgagccg agcttggtct ttgtctggct ctcgaataca
     8641 ggctcctcca cttttatgct gatagcggcc acgatacccg cacgaatatc cgaatattcg
     8701 aaattcttat tgtaatattc cttgatgaca cgacctatag actccttgaa agcggaaagg
     8761 tgcgtaccgc cttgggtggt atgctggccg ttcacgaacg aataatattc ctctccatat
     8821 tggttgctat gcgtgataac cacctctata tcctcccctt tcaggtggat gatcgggtaa
     8881 agaggctcgg tggtcatatt ctcgttcaac aaatccacca gaccattgcg ggaatagaaa
     8941 cgtttgccgt tgtaaataat ggaaagtccc gagttcaaga agacatagtt ctttaatagc
     9001 ccctcgataa actcgtcctt ataatgataa tccttaaaga tctcccgatc cgggacaaag
     9061 aatacctgcg taccgttcgc ctccccggtc ggttggatat ccgattcctc cgtgacgatc
     9121 gccttactat attccacccg cttacactct ccgtcacggt agctggttat caagaaataa
     9181 ctactcaagg cattcaccgc cttgataccc acaccattca aacccacgga tttcttaaac
     9241 gccttgctat cgtatttagc gccggtattc atcttgctag acacatccac gactttaccc
     9301 agagggacac cacggccata atcccgtacg gctaccgtac cttcctcgat agtcacctcg
     9361 atacttttgc cataccccat catgtactcg tcgatagagt tatccagcac ctccttcaac
     9421 aacacataga taccatcatc ggcatagcta ccgtccccca gttttccgat atacataccg
     9481 ggacgccggc ggatatgctc catccagtcc agtgtcttga tgtcatcatc gttatattcc
     9541 gtaggttgtt gtatcgttga attcagctca tccatatctc ttataacttt ttaatatacg
     9601 ctcttcttga tttatgatgc tctcgcttga aataatccca ttgcgcttgt acggcgctat
     9661 tcgtctccag ctccgggtta ctctcggcgt aaacggcacc gatacgctta tagaccggaa
     9721 tcaagtcatt aaataataaa gcgttcacgc ctttactttg atattccggc aagactcctg
     9781 tcaaatacag gtcgattact ttcggtttgc tcttcaacgc tttcagcaaa tgaatccacc
     9841 cgaagggtaa catatgccca cgagcctttt gcaaggctct cgaaaggttg ggcagggaga
     9901 tgccaaagcc aaccaccgca ttatcctctt cccttacgat cagcgttacc aaatcataac
     9961 gcagcatagg gatatacata ttgatataat aatcgatctg cttctcggtc aattgcgcga
    10021 aaccatacaa gggagcgaaa gccgcattca atgtatggaa taccggacgg gcgtaaggca
    10081 taatctcctt agcgttcttg aacttcagca ccttcaatcc gtatttcttc ttcacgatct
    10141 cgccgatacg caaatgcttc tcgggaacgc catccggtat atagatctta aattcatgcc
    10201 aatcttgatc ctttccgtat ccgatacgct ccacttgctt ggggtaatag ggataattat
    10261 aaattgtagc catcgtaccg atctgatcga aaccctcgat caacataccc tcgtgatcca
    10321 tatcggtaaa gcccatcgga ccgtggatct cctccatgcc ttgttcgcgg gcccatttct
    10381 cgacagcgcc aaaaagggca tcaaccacct cgtcatcatc aataaaatca acgaaaccaa
    10441 agcgggcacg tttctgtccc caagcctcgt tactcgggcg attcaccata ccggcgatac
    10501 ggcctaccac cttcccgtcc ttataggcaa ggaagtaaat agcgtcgcac acctcgaacg
    10561 ccggattttt cttcttatcc agcgtcatca tctcttcctc tattaaaccc ggtacgtgat
    10621 agggattacc cttgtataat tcgatattga acttgacaaa cttcttaagc tccttcttac
    10681 tggtaacttc tcttatctct acgctcatcg gtaattttat ttaagcggca aagttacata
    10741 aataatcttt tatcatggca ttataaaaca aatttatacc tttgtaaact cagattcata
    10801 gcataccatg aaaaaaatag ttattaaatt aatattggca tttatcatgt ttgaaggaac
    10861 ctcttgtata aacgatccta ttataatcag ccccgatctg gcgtttcggg cggaagctac
    10921 tacaggggag ggatcgattt ggcatcccga tcgcaataca cttttctggg tagatattga
    10981 aggaaagacg ttatatgagt atataccgga cttgcaaaat tgccgttcat ggcagttcga
    11041 ccgcatggtc tctaccgtcg taccggaaac ggacagtacg gtagtcgtcg ctttacaaaa
    11101 cgagatcata cgtgtaaacc taacggatgg gaacacgaca tccatcgccc caatcccgga
    11161 caataacggg aagattcgtt gcaacgatgg gaaatgcgac ccgtccggac gcttatggat
    11221 cggcaccatg ggatttggcg cgcctaaagg ggctgccagc ctttattgtg tatgggcaga
    11281 cggaaccgtc gaaactaagt tgacaaaagt cacgatctcc aatgggatcg tatggtccgc
    11341 caacaagaaa tacatgtatt acaacgacac acctacccgt aagatcatac gtttccggta
    11401 tgacgatagc tccggtgaca tattgtacga tggcgtagcc gtaaatatac ccgagggcac
    11461 cggctccccg gatggaatga cgatagattg caacgacaac ctttgggtgg ctcaatgggg
    11521 aggtggcggt gtttattgtt acaatcccta taccggcgac ctgttgacaa aaattgtcgt
    11581 accggccccc cacgtagcgt catgcgcttt tggaggggat aagctcgaca cgctttatat
    11641 aacgaccgcc cgtgctggat tgagtgagga acagcttgag gaatatccac taagcggtag
    11701 cgtattctgt tgcaagcccg gagcgaaagg ggtgccggcg aattgtttcc attaagaatc
    11761 cgcgagctta ataaatctaa ttaacacaat tgtcaaccaa atatcaattt aaattgtttc
    11821 ctttgtagac atggcgtgca aaagacgagg cgtgccccgt ctccacaaaa acaaatgcaa
    11881 ataattatac agaatggcaa agaatagacc agcaaaaaaa gataacaata aggagaaaaa
    11941 aggaaaaaag gacaagggtg ttggtaaacg tatgaaaaaa gaagcgatga tccaagccat
    12001 catttccgtt ttccaatcct ctcccaagga acctttcaac tataaacaaa tcagcaagat
    12061 catcggagtc gagaaccaag tgcagaaatt gcaggtggta gacatcctgt atgacttgtc
    12121 cgccgaggat atcatcaccg agatcgaccg tggccgttac cgtctcaacg gattgggaac
    12181 cctagccgta ggaactttcg cacgccgcag caatggaaag aattctttca tccctgaaga
    12241 cggaggtacg ccggtattta tcgctgaacg taattccggg catgccatgg atggagacaa
    12301 agtaaaagta cagcttttcg ccaaacgtaa aggtgccgag ccggaaggtg aggtcgtgga
    12361 aatccttgag agcaaggagc gtactttcgt aggtaaactt caagtagcta aaggctttgc
    12421 cttcttgatt acggaaaaca agacgttggc taacgatatt ttcatcccta aggataaact
    12481 gaaagggggc aagaacggcg acaaagcgat cgtacgtatc gtggaatggc cggatgaagc
    12541 caagaatcca ctgggtgagg tcatcgatat attaggtatc gccggacaga ataccgccga
    12601 gatgcatgcg atccttgccg aattcggatt gccttacaaa tatccttcct cggtagaaaa
    12661 agcggcggat aagatcccag aagcgatctc tccggaggaa attgagaacc gggaggattt
    12721 ccgggggata acaaccttca cgatcgaccc gaaggacgcg aaagacttcg acgacgccct
    12781 ttccgcacgc cgtttggata acgggaactg ggaggttggc gtacatatcg ccgacgtaac
    12841 acattatgtg aaaacggacg gtgtcatcga taaagaggcg caaagccgtg cgacttccgt
    12901 ttatctggta gaccgtacga taccgatgct tcctgagcga ctttgcaacc aaatatgctc
    12961 tttacgtccc gacgaggaaa aattatgctt ctccgctgtc ttcgaactaa atagcgatgc
    13021 cgtagtgcaa aactcccgga tctgccgcac gatcatcaag agcgaccgcc gctttaccta
    13081 tgaggaggca caagaagtga tcgaaaccgg cgagggagat tataaagagg agattctagc
    13141 cttgaacgat cttgccaaga aattgcggga acgccgtttc aagagtggcg ctatcaactt
    13201 cgaccgctat gaggttaaat tcgagatcga cgaacaaggg aaaccggtcc gtgtttattt
    13261 caaggtctca aaagacgcta ataagttaat cgaggagttc atgctattgg caaaccgcac
    13321 cgtagccgag ttcgtgggcc gtcctcctaa aggaaagact aagaagacat ttgtttatcg
    13381 tatccatgag cttccggacc cagataaaat ggagaatttc gcctctttta tccgtcgctt
    13441 cggctataag ttgaaaacag acggcacgaa gacggatgtc tccaagggaa tcaactcctt
    13501 attagacaat gtacaaggaa agccggaaga gaacttgatc gagacagtgg cgatccgtgc
    13561 catgcaaaag gcccgttact ccacggagaa tatcggtcac tatggcttgg ctttcgaata
    13621 ctatacacat ttcacctctc ctatccgccg ttatccggat atgatggtac accgattgct
    13681 ggaacgttat ctagccggtg gccgtagcgt tatacaaaag aagtatgagg atttatgcga
    13741 tcattgttcc agcatggagc aagtcgccgc caacgcagag cgtgcatcca tcaaatataa
    13801 gcaagtagaa ttcatgcagg ataagcttgg catggtattc gacggcgtta tctccggtgt
    13861 caccgaatgg ggactttacg tagaactgaa cgagaataaa tgcgaggggc ttgtaccaat
    13921 ccgtgatctg gatgacgatt actatgagtt tgatgagaag aattattgtt tattgggccg
    13981 tcgcaagaaa cgtcaatatc gtttgggaga ccctatcact atcaaagtag cgcaagcgaa
    14041 tctggaacgt aagcaactcg atttccaatt agcggaataa ggcctttttc aaagtaagta
    14101 taacttcatc agacaacgaa gttatactta cttaggcatt ttgattatac ttactaggac
    14161 aagtaagtat aatttacttt ttatcaccaa tacataagtc ccagcgcccc acaagcgatc
    14221 agcccgattc ccaacaacgc atagaagata cgtgcgccgc cacgaccgaa ccagttcacg
    14281 aaagtcatcg ccccgctggt tttaaagtac caatcaaaat tacagatcgc cgctacgatt
    14341 gagaacaatc ccaaagcgat aaacaaggat aagataaagt attcggaagg atccatagac
    14401 ttacttaacc tctacagtac gtgaaccgtc cggattctcc gagatcgtga catttaccac
    14461 atctccgggt aacaactcat ctattttctc cggccattca ataaaacata aagctccgct
    14521 atagaaatag tcttctgttc cgatatcctc cgcctcactc aatttattga tccggtaaaa
    14581 atcaaaatga taaatcaatt ctcccgtcgt atcgctacgg tactcattga taatagcgaa
    14641 tgtgggactg ttgatcacat cctccacacc caattcctca cagatcgcct tgataaaggt
    14701 agtcttaccg gcccccatcg gaccatagaa ggcaaagacc gtacgatcat ccatcccggc
    14761 gataaactcc ttagccgcct catggatctt atccaaactt tctattttca gtgtgctcat
    14821 agcattcgtg tttacagttt atatggactg caaagttcgt gatatttatg atatacgcaa
    14881 cttttcggca tattatcatt tcggttccat cgtaataaac ggcaccaaca tctcctccat
    14941 cgagattcct ccgtgctgga atgtattttt ataataggat acgtaatagt tataattatt
    15001 cggataagcg aagaaattct ctccgtaagc gaaaatatac ttactactta gattcgggga
    15061 gggaagtcct actttttccg gatcccggat ctcgaatacc tctttcggat tgtagttcaa
    15121 gttcttgcct actttatagc gtagattggt attcgtattc ttatcaccta tcaccttgat
    15181 cggattcgtt acccggatcg ttccatgatc ggtcgtaacg attacttttc ctccccgctc
    15241 ggcgattcgt ttgaataact cgagcgtaga agagtgctgg aaccatgact tagtcaaact
    15301 gcgataggcc gcctcgcttt gcgccaactc gcggatcatc ttactctccg tacgagcatg
    15361 cgaaagcata tccacgaagt tcagcacaat cacattcagt tgattacgag taagagaagg
    15421 gatcgtagcc aacaatttct ctccatattg ggaatcgtgt actttattat atgagaaggt
    15481 atatttctta cggaaccgat cgatctgggt ttgaatcaat ggagcctcat tcaaattctt
    15541 accttcctcg ctctcctcat ctacccacaa atccggaaac atctgctcta tttgcgaagg
    15601 catcaagccc gagaatatag agttgcgggc atattgcgtg gcggttggca gtatgctata
    15661 atacaagctc tcgtcaaacg taaaatactc agtaagcaat tcttttacca cccgccattg
    15721 atccagccgg aaattatcga tcaatataaa gaaaaccttc tcgtcattat ccaacattgg
    15781 gaaaaccttc ttcttaaaca ggtcggggct catcaacggg cgatcggccg gattctgtat
    15841 ccagtccaca taattcttct tcacgaattt ggcaaaagcg ttattggcct cttccttctg
    15901 catacggagc atatctgtca ttgccacttg gctgctttcc agttccaatt cccagtacac
    15961 tagtttctta tagacctcca tccagtcgtc tgtggtcaag gaatcattga tttgcatacc
    16021 tatacgaccg aattcctgct gataacccac cgtggtcgtc tcggagataa tcacgttctt
    16081 atggacattc ttcttgatag agagaagcaa ttggttggga tttaccggtt tgatcaaata
    16141 atccgcgatc ttatttccga tcgcctgatt catgatactt tcctcctcac ttttagtcac
    16201 catcacgacc ggcacattcg gagcgatctc cttgatatgc gacagcgtct ccaatcctgt
    16261 caagccgggc atattctcat cgagaaaaat aat
//
LOCUS       DBMDTB010000089        16262 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_1143_length_16262_cov_9.674711, whole genome shotgun sequence.
ACCESSION   DBMDTB010000089 DBMDTB010000000
VERSION     DBMDTB010000089.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 16262)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 16262)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16262
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1143_length_16262_cov_9.674711"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..1469)
                     /locus_tag="ACZPB4_13080"
     CDS             complement(<1..1469)
                     /locus_tag="ACZPB4_13080"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0031419 - cobalamin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobalamin-dependent
                     ribonucleoside-diphosphate reductase"
                     /protein_id="HIR1099182.1"
                     /translation="MDRKTYTFDEAFKASLDYFTGDELAAKVWVNKYALKDAFGNIYE
                     ESPNDMHHRLASEIARVEKKYPNPLSEQELFDLFDHFRYIVPQGSPMTGIGNDYQIAS
                     LSNCFVIGLDGQADSYGAIIRIDEEQVQLMKRRGGVGHDLSHIRPKGSPVKNSALTST
                     GLVPFMERYSNSTREVAQDGRRGALMLSVSIKHPDSEAFIDAKMTEGKVTGANVSVKI
                     DDDFMNAAVNGGTYKQQYPIDSDSPVYVKDIDASGLWKKIIHNAWKSAEPGVLFWDTI
                     LRESVPDCYADLGFRTVSTNPCGEIPLCPYDSCRLLAINLYSYVVNPFTPDAYFDYDL
                     FKKHVGLAQRIMDDIIDLESEKIEMILAKIDSDPESMEVRQTERHLWEKIQRKTLQGR
                     RTGVGITAEGDMIAALGLRYGTEEATDCAELIQKTLALAAYRSSVMLAKERGAFEIFD
                     AKREEKNPFINRLREADPALYEDMLKYGRRNIACLTIAPT"
     gene            complement(1727..3124)
                     /gene="dnaA"
                     /locus_tag="ACZPB4_13085"
     CDS             complement(1727..3124)
                     /gene="dnaA"
                     /locus_tag="ACZPB4_13085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003688 - DNA replication origin binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0006275 - regulation of DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HIR1099183.1"
                     /translation="MQTDYQTLWNKCLAVIKDIVPKAAFDTWFVPIVPLSYEDKKFTI
                     QVPSQFFYEYLEEKYVNVLKVTLYRVIGQGTILNYRIMVDKTTGGTVDYPAENASTAV
                     KKVTPKDANKAPNPFMTTAPQDLDPQLNPKYNFDNYFEGTSNKLVRTAGEAVAQNPGK
                     TTFNPLFIFGPSGVGKTHLCHAIGTRIRELHPEKKVLYVSSHLFRVQFTDAIRKNTTN
                     DFLNFYQNIDVLLLDDIQELIGMDKTQNTFFHIFNHLHQLGKQLILTSDKPPVDLQGM
                     EERLITRLKWGLTAELSRPDLDLRKKILKNKINHDGIMIPDEVFNFIANNVTENVRDL
                     EGILVSLMANAVINNREIDLPLTKRVVSQAVRLEKKQISVQMIQEIVCKYFNLEQSVI
                     QTNSRKREIVQARQITMYLAKKYTDSSFSHIGKIVGKKDHATVLHACKTIKDQIETSK
                     SFRSSVEEIEVLLKN"
     gene            complement(3491..4375)
                     /locus_tag="ACZPB4_13090"
     CDS             complement(3491..4375)
                     /locus_tag="ACZPB4_13090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015914 - phospholipid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MlaD family protein"
                     /protein_id="HIR1099184.1"
                     /translation="MKSVFTKEAKIGLVTIVSLALLYLGINYLKGINLFQPVNHYYVS
                     FSNVKGVTISSPVFVDGFKVGLVRDIIYDYDTTGKIIVEVSLEDKMRLNKGSYIAVVN
                     TFLSGAELHIHLNTYVDDFLKPGSTLEGRMEEDMMQSVQEKILPSVENLLPKIDTILG
                     SLQTLIAHPALAQSLNHIEKTTSNLEVSTRQLNQMLSKDVPGIVNNLKTMTDNFSEVS
                     ANLKELDLATTVNSINATLANLKLTTDKLNSTDNSIGLLLNDKGLYDNLNSTMDNASK
                     LLLDLRENPKRYVHFSVF"
     gene            complement(4413..5576)
                     /locus_tag="ACZPB4_13095"
     CDS             complement(4413..5576)
                     /locus_tag="ACZPB4_13095"
                     /EC_number="3.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HIR1099185.1"
                     /translation="MSKKSFLYINLLFALFFFLPGLQAREKTFTVVIDAGHGGKDPGA
                     RGANINEKEINLAVALKLGRLIENNAEDVRVIYTRKTDRFIELDERANIANRNKADLF
                     VSIHTNAVKRGSTVQGTETYTLGLARSEENLEVAMSENSAILLEDNYQQRYEGFDPNS
                     SESYIIFEFMQNKHMEQSISLASEIQKSFGACKRVDRGVRQAGFLVLRKTSMPSVLVE
                     LGYISNRQEEQFMRTAAGQNKLAEALYDAFCKYKKNYDRRKGNISGVVAAPVANEETP
                     PPGSEADILNKKQQATKQKTSVSSTTSVNRNTKGKVIYKIQFLTSNKKLPANSRLFKG
                     YKNVDFYVEKGIYKYTYGETSDFNSIRKMRRTIAKDFKDAFIIAFKDGKKVKY"
     gene            complement(5712..6158)
                     /gene="rplI"
                     /locus_tag="ACZPB4_13100"
     CDS             complement(5712..6158)
                     /gene="rplI"
                     /locus_tag="ACZPB4_13100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HIR1099186.1"
                     /translation="MQVILKEDVVNLGYKDDIVTVKDGYGRNFLIPTGKAVIASESAK
                     KVLAENLKQRAHKLAKIKEDAQTLAAKLEGVALTIGAKTSSTGTIFGSVTNIQVAEAL
                     AKAGFENIDRKIIYIKESVKEVGSYKAVLKLHKEVSVEVPFEVVSE"
     gene            complement(6180..6449)
                     /gene="rpsR"
                     /locus_tag="ACZPB4_13105"
     CDS             complement(6180..6449)
                     /gene="rpsR"
                     /locus_tag="ACZPB4_13105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005637107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HIR1099187.1"
                     /translation="MAATQSEIRYLTPPSVDVKKKKYCRFKKNGIKYIDYKDPEFLKK
                     FLNEQGKILPRRITGTSLKFQRRVAQAVKRARHLALLPYVTDLMK"
     gene            complement(6452..6808)
                     /gene="rpsF"
                     /locus_tag="ACZPB4_13110"
     CDS             complement(6452..6808)
                     /gene="rpsF"
                     /locus_tag="ACZPB4_13110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HIR1099188.1"
                     /translation="MNNYETVFILTPVLSDAQMKEAVEKFTNLLKAQGAEIVNEENWG
                     LRKLAYPIDKKTTGFYQLVEFKADPSVIATLELNFRRDERVIRFLTFRQDKYAAEYAA
                     KRRNLKSSKETVKENN"
     gene            complement(6910..8679)
                     /locus_tag="ACZPB4_13115"
     CDS             complement(6910..8679)
                     /locus_tag="ACZPB4_13115"
                     /EC_number="3.1.6.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012056244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004065 - arylsulfatase activity [Evidence
                     IEA];
                     GO_function: GO:0008081 - phosphoric diester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HIR1099189.1"
                     /translation="MTKLGVLFSVLGVGAGCIPAFAQKQLPNIIVMLSDDQGWGDLGF
                     TGNTFVQTPNIDRIAHEGTILENFYVCPVSSPTRAEFLTGRYHVRSGVNSTTGGGERF
                     NLGEKTIAEYFREAGYATSLFGKWHSGTQYPYHPNARGFEEFYGFCSGHWGNYWNPVL
                     EHNGEIISGEGFIIDDLTDKALDYIRDHKEHPFFMFLSYNTPHSPMQVPDSWWNRVKD
                     RTLSQRATFPEQEDTTFTKAALALAENLDWNIGRVLSLLHSLDLEQETIVIYFSDNGP
                     NSFRWNGGMKGRKGSTDEGGVRSPFCIRWPGHIRKGAVETQLSGAIDLIPTLLGLAGI
                     EYTPLRKLDGIDWGQRLLDEKAPAMDRVLYSYWGGKTSVRIPYYLLDAEGHLYKTDID
                     REQRKDVSDKEPEIYERMKRYSNWFKDELLADFPKKDTRPFIIGHPQETYSKLPARDA
                     RISGPIERSNRYPNCSYFTNWKNPEAEISWNVEVEESGLFEAFIYYTCDKRNIGSTFE
                     LRTDRDAENLVFTLDQVNDQPMLGADLDRVLREESYVKGFAPCSVGTIPLSKGTATLS
                     LQAKTIRNEEAMNFWMLVLKRVK"
     gene            complement(8713..10257)
                     /locus_tag="ACZPB4_13120"
     CDS             complement(8713..10257)
                     /locus_tag="ACZPB4_13120"
                     /EC_number="3.1.6.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012056243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase family protein"
                     /protein_id="HIR1099190.1"
                     /translation="MKIKLSLLATGLLYVPVVFAQKQPNVVIILADDMGYGDVGCNNP
                     YARVRTPAIDQLARNGIRFTDAHSAGALSGPSRYGLVTGRYFFRTPKKSEYWGYLSPY
                     IEPERLTIGSLMRNAGYTTACVGKWHLGLDWQLKDDSKPQILTPKKFGYTNTDFSAPV
                     KRGPTELGFDYSFILPASLDMPPYAFVRNDRVVDPDVILTADAYPKKQDETVYAWDRK
                     HTNENDIYWERGVWWRNGEMSRSFKFEECFPTIVDEGIAFIDREGRKDKPFFLYMPLT
                     GPHTPWLPTVQFKGSTELGTYGDFMGDIDNVVARVNAKLKELGLEKNTIVIFASDNGG
                     AWEEEDIQQYGHQSNWSRRGQKGDAWDGGHHVPLIVHWPDHIKYPGVCSQTVGLVDIL
                     ATLADLTGQSLPKGQAEDSFSFKKVLDGDMNASTRDQIMYLSGSGKLAIKKGDWKYID
                     CLGSGGFTAPARLSPVKNGPKGQLYNMRTDSLESNNLFLREKGIANELSALLKKLLDQ
                     GYSRPQ"
     gene            complement(10275..11795)
                     /locus_tag="ACZPB4_13125"
     CDS             complement(10275..11795)
                     /locus_tag="ACZPB4_13125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RagB/SusD family nutrient uptake outer membrane
                     protein"
                     /protein_id="HIR1099191.1"
                     /translation="MKINKIYIVSLCALFLSSCNNFLDEQPTGTMTTDSKLTSKESAL
                     ALTNSAYLKNTVFNKMTPGWGCNTILLLEYMTGKATSENSQSNYKDFQDLLVSDRSLY
                     IEDWWQDCYAGIANCNLALQKLGEFENLDASLVNGYMAEVKFMRALYYFYLVRIFGDV
                     PKITTVQSELGELQVSRAPVKEIYDEIIIPDLLEAEQSDLAFSDHTGRVSMGAVKALL
                     ADVYLTYAGYPLQGGKSYYAESAKRSLEVIKSNEYTLFTDYESLRLPSQNNKGEFIYQ
                     VQFSLNKRHNESVRIFLPSRSGISAYDLEYGSLIPTKEFVESFEKGDKRTEEKQYFFT
                     NYKGHPSKFSPGAAELEFMDLNGYYIYKFFDQVAIDNTAKSDLNWSVYRYTDVLLMYA
                     EAQVNADGTPNQQSIDIVNQIRGRAGLAPFKQTNASAFLEEVWDQRYFDLCYENKMWF
                     DMLRTRKIRDDKSGEYVDFIGYKTNWGKVYTETQLLFPIPLSERQANPNLTQNQGY"
     gene            complement(11808..15125)
                     /locus_tag="ACZPB4_13130"
     CDS             complement(11808..15125)
                     /locus_tag="ACZPB4_13130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HIR1099192.1"
                     /translation="MNRNKSIRVAILCLSLAMAGSLPIDAQKVTFHEGSISLKQAFEK
                     LESSSAYKIAYNDSQLDVSRKVSMDQKDMEVLQVLSQLLKNTGYTYKINGNYVIIVPE
                     EVKTVKGKKQVSGVIVDTNGDPVIGANVVEKGTTNGTITDLDGKFTLEVNDNSVLQVS
                     YIGYNTQEVSANGKTSFSIKLGENTQTLDEVVVVGYGTMKKSDLTGSVTNVKAEKLLS
                     KPVVNVGQALAGKASGVEIFENGGTPDGKVRVRIRGNNSINSSNEPLYVVDGVIGVSN
                     INLLNPSEIESLEVLKDASATAIYGARGANGVIMITTKRGIKNEKAQISYDGYVSIGK
                     MAKKLDLMNASEWWQNYNTTMDNGQKYDPEGYAQGKYKKVTPADLPNLFDANGNPLYD
                     TDWQDEAYQTAINHNHQVSIRGGADKTLYSVHLGYMHKDALMRNGFLDRYSGRINLDS
                     QLRDWLKMGANMSFNYNKGNDNYKSYGVKRLVQEAIPLIPVKYPDGSWGSNRDFPGAV
                     QDTPSRYLEEMVNETSNIQTIADLYLDFKITDDLNFKSTFAVDASNRKRNYYSGKDLI
                     QFSKTAGGIATIETLKEMYWQNENYFNYNKEFNKNNRMNVMLGLSWQQRVAESVEATS
                     QNFSDDFYQWHNLGAGTVTIPSKSEDYGWSINSYFARINYTLKDRYLFTATGRYDGSS
                     KFGKNNKYAFFPSFAFAWRASEESILKGVNWLNNLKVRTSIGETGNQEIGNYAFYQKL
                     GSENTIFGNDYYTALYRSTFGNPDLKWEKTLQWDAGVDVSVLNQRIDLSLDYYYKKTS
                     DLLLEAPIPGTSGLNTIMRNIGSVQNQGFELTLNTHNIQTDNFNWMSTVLFNVNRNKI
                     LNLGENDEDIYPKPRHAQGDMLILRVGEPVGSLWGLRRLGTWGEDEAAEAAKYNRLPG
                     DVKYEDLNGDGKINSEDNTIIGCTSPDWTMTISNTFLYKNFDFSFDLRFVFGNDVVNC
                     ATHNAEDRSGVANGFKSNLNAWTPQNQHTMVAQRRPMKSYYDSYPDSHWMQNGSFVRG
                     QNFVLGYTFSKSLLQKIKLQDLRIYASAQNLFCITKYKGYDPEVTTYEDAAFGQGIDD
                     FSEPKARTFTFGLNVKF"
     gene            complement(15258..16238)
                     /locus_tag="ACZPB4_13135"
     CDS             complement(15258..16238)
                     /locus_tag="ACZPB4_13135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecR family protein"
                     /protein_id="HIR1099193.1"
                     /translation="MSPIKKILKYFFHHSFSGEMVDRVHQRLAEPGDEREKEEALRDI
                     WNEIGFPEADKRSEMAFARLENTLGVRPRRRLRIPAWVRIAAIWLIPLLSLGVSYYLY
                     RDARDVKKLAFMEQFVPSGKRERITLPDGSEVWLNSGTLLLYPSAFIGQSREIYLVGE
                     GYFKVRKRPEQPFIVRTKAMRVQVLGTEFNLSAYPGQEKITTTLEEGSLKILPDDPSV
                     APCILRPNEQLVYIPSRGKMDVRQVVASDYSDWKEGGLLFNNDSFEEILKTLERVYNV
                     KVHLRTSAYHSNRLTIHFNKHESLENIMMLVKEMIPGLEYQIKEDGIYID"
BASE COUNT         4487 a         4210 c         3053 g         4512 t
ORIGIN      
        1 gtcggagcga ttgttaagca agcgatatta cgacggccgt atttcaacat atcctcatat
       61 aaagcaggat cagcctcacg caaacggttg atgaacggat ttttttcctc acgcttcgca
      121 tcgaatatct caaaggcacc acgttctttc gccaacatta cggatgaacg ataagcggcc
      181 aaagctaatg tcttttgtat aagttccgca caatcggttg cttcttctgt tccataacgc
      241 aaacctaaag cggcaatcat atcgccttcc gccgtaatgc ccacacctgt acggcgtcct
      301 tgcaaagtct ttcgttggat cttttcccac aaatgacgct ctgtttgtct tacctccatg
      361 gattccggat ccgagtcgat cttagccaag atcatctcga tcttctccga ctctaaatca
      421 ataatatcat ccataatccg ctgggccaaa cctacatgct tcttgaacaa atcataatcg
      481 aaataagcgt ccggagtgaa cggatttacc acatatgaat ataaattgat cgctaacaaa
      541 cggcaactat catacggaca aagaggtatc tcgccacaag gattcgtgga aaccgtacgg
      601 aaccccagat ccgcatagca gtctggtaca gactcacgta agatcgtgtc ccagaatagc
      661 acacccggtt cagcggattt ccaagcgtta tgaataattt ttttccataa gccagaagca
      721 tcgatatcct tcacataaac gggagaatcc gaatcaattg gatattgttg cttataggta
      781 ccgccattaa ccgcggcatt catgaaatca tcatcaatct tcacagatac atttgcacct
      841 gtaaccttac cttccgtcat cttagcgtcg ataaacgcct ccgagtccgg atgtttaata
      901 gaaacgctca gcatcaaagc tccacgacgg ccatcttggg ccacctcacg ggtggaattc
      961 gaataacgtt ccataaacgg aaccaacccg gtagaagtca acgcagaatt cttaaccgga
     1021 gaacctttcg ggcgaatatg cgaaagatca tggcctacac caccacggcg cttcattaat
     1081 tgtacctgtt cttcgtcaat acgaataatc gcaccatacg aatccgcttg cccgtccaat
     1141 ccgataacaa aacaattaga gagtgaggca atttgataat cattgccaat tcccgtcatc
     1201 ggacttcctt gcggaacgat gtagcggaaa tgatcaaaca ggtcgaaaag ttcttgttcc
     1261 gacaacggat tcggatactt tttttccaca cgggcaatct cacttgccaa gcgatgatgc
     1321 atatcattcg gagattcctc atagatattt ccaaacgcat ccttcaaggc atatttattt
     1381 acccatactt tagcggcgag ctcgtcaccg gtaaagtaat ccaatgaagc cttaaacgct
     1441 tcgtcaaaag tgtaagtttt acgatccaca attattatat ttattttgcg actgcaagtt
     1501 tacgcatact ttaccagtta tccaaattac cctacgttaa aaagaatact tattgaaaag
     1561 ttttccaaaa ccaaactcgc aaccccacat tttcaactac ttaaacaaaa ctaagcatca
     1621 aatagttttc caaaaagaaa acttaacact tacacagatc tcccaaaaca aagaaggacg
     1681 cctctttaga gagacgtcct tatcctacta tatagggatt cttaatttag ttcttgagca
     1741 agacctcgat ttcctcaacg gaagaccgga aagacttact agtctcaatc tggtctttga
     1801 tcgtcttaca agcatgcaag acagtcgcat ggtctttctt tcctacgatc tttccaatat
     1861 gggaaaaaga ggagtccgta tatttcttcg ccaaatacat cgtgatctga cgggcttgca
     1921 cgatctcacg tttacgggaa ttagtttgga taaccgattg ctccaagttg aaatacttgc
     1981 aaacgatctc ctgaatcatc tgtacggaga tctgtttctt ctccaaccga accgcttggc
     2041 taaccacacg tttcgtcaac ggcagatcga tctcacgatt attgataact gcattagcca
     2101 ttaaagaaac gagaatacct tccaagtcac ggacattctc cgtcacatta ttagcgataa
     2161 agttaaagac ctcatccgga atcatgattc cgtcatggtt gatcttattc ttcagtatct
     2221 ttttacgtag atccagatcc ggacggctca actcagccgt caatccccat tttaaacggg
     2281 tgatcaagcg ctcttccatc ccttgcaaat ccacaggagg tttatcagaa gtcaagataa
     2341 gctgcttacc taactgatgc aggtggttga aaatatggaa gaatgtattt tgagtcttat
     2401 ccataccgat caactcctgt atatcatcca acagcagcac atcgatattt tgatagaaat
     2461 tcaagaagtc attagtcgta ttcttacgga tagcatctgt aaactgtacc cggaacaaat
     2521 gcgaagatac atataacact ttcttttccg gatgcaactc ccgaatacgg gttccgatcg
     2581 catggcataa gtgagtttta cccactcctg acgggccaaa aataaacaac gggttaaacg
     2641 tagtctttcc cggattctgg gcaacagcct cacccgccgt acgaaccagc ttattgctcg
     2701 taccctcgaa ataattatca aaattatact tcgggttcaa ctgagggtcc aaatcctgcg
     2761 gagcagtcgt cataaaagga ttcggagcct tgttagcgtc cttgggagtg actttcttta
     2821 cagcggtgga agcattctcc gccggataat caaccgtacc accagtggtc ttatccacca
     2881 tgatacggta gttaagaatg gttccttgac cgattacacg atacaatgta actttcaaaa
     2941 cattaacata cttctcttcc agatactcat agaagaattg actaggcacc tgtatggtaa
     3001 acttcttgtc ttcgtatgat aacggaacga taggtacgaa ccatgtgtca aaagctgcct
     3061 taggcacaat atcctttatg accgcaaggc acttattcca caatgtttga taatcagtct
     3121 gcatgttttc tttctctccc actaatactt tttacattcg gactacaaag tttagaaatt
     3181 aattccgaaa aaaaaagtgc tattttgttt ggtaaatatg aattttcaat atccctttta
     3241 gattcagata gttactaata cctatctgat ttactgctat ttagatcgac caacgctcaa
     3301 aaacccttta ttttagagac ctctacaaaa gcgtaaacgc tgacgtccgg tgacggaata
     3361 aggcctcagg aagtatctat ctcactttac ctaaaggcct tatgcgtata atcagcagga
     3421 gtcccctaac tttttgtcta attagaatga ttctaaataa cgtcttttat actatgattt
     3481 tttaacataa tcaaaaaaca gagaaatgga cgtatctttt cggattctcc ctcaaatcta
     3541 gcaatagctt ggaggcgttg tccatcgtgc tgttcagatt atcatacaat cctttgtcgt
     3601 tcaacaataa gccgatgcta ttatccgtcg agttcaattt atccgtagtc aacttcaagt
     3661 tcgccaaggt cgcattgatg gaattgaccg ttgtagccaa atccaattct ttcaagttgg
     3721 cgctcacctc cgagaaatta tccgtcatcg tcttcaagtt attcacgata cccggtacat
     3781 ccttactcaa catctgattc aactgacggg tagacacctc taggttgcta gtcgtttttt
     3841 cgatatgatt caaggattga gccaaggccg gatgagcgat caaggtttgc aagctaccca
     3901 aaatcgtgtc gatcttcggc aaaaggttct caacgcttgg caagatcttc tcctgtacgg
     3961 attgcatcat atcctcttcc attcgtccct cgagcgtaga acccggcttc aaaaagtcat
     4021 ccacgtaagt gttcaaatgg atatgcaact cagctccgct taagaaggta ttgacaaccg
     4081 ctatataact tcccttattc agcctcatct tatcttccaa actaacctca acgatgatct
     4141 taccggtcgt atcatagtca taaataatat cacgaaccaa tcccacctta aaaccatcca
     4201 caaatacagg gctggaaatc gtcaccccct ttacgttgct gaatgatacg tagtaatggt
     4261 tcaccggttg aaacaggtta atacccttca gataattaat gcctaaatac aataacgcca
     4321 gacttacgat cgtcacaagt ccgatcttcg cctctttagt gaatacactt ttcatttcct
     4381 ttatttataa tgtataattt attcctatat cattaatatt tcaccttctt cccatcctta
     4441 aaagcgatga tgaaggcatc tttaaaatcc ttagcgatcg ttcggcgcat cttccggatc
     4501 gagttaaaat ccgaagtctc gccatacgtg tatttataga tacctttctc cacatagaaa
     4561 tccacgttct tgtacccctt aaataaccgg gagttcgcag gaagcttctt attggaagtc
     4621 aagaattgta tcttatatat aacctttcct ttcgtgttcc tgttcacgga agtggtagaa
     4681 gaaactgagg ttttctgttt tgtggcttgc tgttttttat ttaagatatc agcctcgctc
     4741 cccggaggcg gagtttcctc attcgctacg ggagcagcga caactccgga aatatttcct
     4801 ttacggcgat cgtaattctt cttatatttg caaaaagcat cgtacaacgc ttccgccaat
     4861 ttattttgtc cggcggcggt tctcatgaac tgctcttctt gacgattcga gatatacccc
     4921 aactcgacca gaacactggg catgctcgtt ttgcgaagca ccaaaaaacc agcctgtctt
     4981 acgccacggt ccacccgctt acaagccccg aacgatttct gtatctcgga agccagacta
     5041 atactttgct ccatatgctt attctgcata aactcgaaaa tgatatatga ctccgaagag
     5101 ttcgggtcaa acccctcata ccgttgttga taattatcct ccaacaagat cgctgagttc
     5161 tcgctcatag ccacctctaa gttctcttcg ctacgggcca aacccagcgt atacgtctcc
     5221 gtaccttgca cggtacttcc acgctttacg gcattcgtat ggatagacac gaaaagatct
     5281 gccttattgc ggttcgctat attcgcacgt tcgtccaact cgataaaacg atccgtctta
     5341 cgagtataga tcacacgcac atcctccgcg ttattctcta tcaatcgacc taattttaag
     5401 gcgacagcga gatttatctc cttctcatta atattcgccc ctctagcgcc cgggtccttc
     5461 ccgccatgcc cagcatcgat cacgaccgta aaagtcttct ctctcgcctg aagtccgggc
     5521 aagaaaaaaa acaacgcaaa tagcaagtta atatatagaa aagacttttt gctcactttc
     5581 taaaattatt gcaaattcgg gaacaaatgt agcgcttttt tgctgattga cagatgtctt
     5641 tttttataat taaaacaaaa aaagagggca gtttcgaaac taccctcttt tatgatatat
     5701 taaagtatct attattcaga aacaacctcg aaaggaacct caacggaaac ctctttgtga
     5761 agtttcaaaa cagccttata gctacctact tccttaacag actccttgat atagataatc
     5821 ttacgatcga tattctcgaa accagcctta gccaaagcct cagcaacttg gatattcgtt
     5881 acagaaccga agatcgtacc tgtagagcta gtcttagcac caatcgtcaa agctacaccc
     5941 tctaacttag cggccaaagt ctgagcgtct tccttgatct tagccaattt gtgggcacgt
     6001 tgcttcaagt tctcagccaa tactttctta gcagactctg aagcgatcac tgccttaccc
     6061 gtggggatta gaaagttacg tccgtaaccg tcttttactg ttacgatatc gtctttgtag
     6121 cctaaattca ctacatcttc tttcaaaata acttgcatat tctgtctcct cttaattaat
     6181 tatttcatca aatcggtcac gtaaggaagc aaagccaagt gacgagcacg ctttacagcc
     6241 tgagccacac gacgttggaa cttcaaggaa gtaccagtga tacgacgcgg aaggatctta
     6301 ccttgctcgt tcaagaattt cttcaagaat tcaggatcct tataatcgat atacttgata
     6361 ccgttctttt tgaaacggca atattttttc ttcttaacgt ctactgaagg cggagttaaa
     6421 tatctgattt ctgattgagt tgctgccata attaattatt ctcctttact gtttctttag
     6481 atgatttcag atttcttctc ttagctgcat attctgcggc atacttgtct tgacggaaag
     6541 tcaagaagcg gatcacacgc tcgtcacgac ggaagttcaa ttccaatgta gcgataacac
     6601 tcggatctgc cttgaattca accaactggt agaagcctgt tgtcttcttg tcgataggat
     6661 aagctaactt gcgcaagccc cagttctctt cattcacgat ctcagctcct tgagctttca
     6721 gaaggttcgt gaatttctct accgcttcct tcatctgagc gtcagacaaa acgggagtca
     6781 aaatgaaaac ggtttcgtaa ttgttcataa aacgctgttt aatattgatt aataaaaaat
     6841 tttgcggtgc aaaggtagtg attatttgat aactggcaaa tagttataca acttttttca
     6901 atctcagact catttcactc gttttagcac caacatccaa aaattcatgg cctcctcatt
     6961 ccggatcgtt ttcgcttgca aggataaagt ggccgtacct ttcgatagag gaatcgtacc
     7021 gacagagcaa ggagcaaatc ctttcacata agactcctcc cggagaaccc tatccaaatc
     7081 cgcaccgagc atgggttggt catttacttg atccaatgta aatacaagat tctcggcatc
     7141 ccggtccgta cgaagttcaa aagtagagcc tatatttcgt ttatcgcaag tataatagat
     7201 aaaagcctcg aacaagccgg attcctccac ctccacattc cagcttatct ccgcttccgg
     7261 gtttttccaa ttcgtaaaat aagaacaatt cggataacgg ttggagcgtt cgatcgggcc
     7321 agatatcctc gcatcccggg ccggtagctt tgaataggtt tcctgcggat gaccgattat
     7381 aaacggacgg gtatccttct tcgggaaatc cgccagtaac tcatccttaa accaattcga
     7441 ataacgcttc atccgctcat atatctcggg ttctttatcc gatacatcct tccgttgctc
     7501 acgatctata tccgttttat ataaatgacc ttccgcatcc aatagataat atgggatacg
     7561 cacactcgtc ttacctcccc aataactata taaaacccga tccatagcag gagctttctc
     7621 atccagcaat cgctgtcccc aatcgattcc gtccagtttc cttaacgggg tatattctat
     7681 tcccgccaaa cctaataaag tagggattaa gtctatagcc ccggacaact gggtttccac
     7741 ggcccctttc cttatgtgtc ccggccaacg gatacaaaac ggcgaacgaa cacccccttc
     7801 atccgtagag ccttttcgcc ctttcatccc accattccac cggaaactat tcgggccgtt
     7861 atccgagaaa taaataacaa tcgtctcttg ttccaaatcc aatgaatgta acaaagacaa
     7921 tacacgtccg atattccaat ctaaattctc ggccaaggcc aaagccgctt tcgtaaacgt
     7981 agtatcttct tgctccggga aagtagctcg ctgcgacaag gtacgatctt ttacacggtt
     8041 ccaccaacta tccgggactt gcatcggact atgaggtgtg ttataagaca agaacataaa
     8101 gaatggatgt tctttatgat cacgtatata atccaaggct ttatcggtca gatcatctat
     8161 gataaagccc tcgcccgaaa taatctctcc gttatgttcc aacaccgggt tccaataatt
     8221 cccccaatgc ccggaacaaa aaccatagaa ctcctcgaag ccccttgcgt tcggatggta
     8281 gggatattgc gtaccactat gccattttcc aaatagagag gtagcgtatc cggcctcccg
     8341 gaaatattcc gcgatcgttt tctctcccag attaaagcgc tcgcctcccc cggtcgtaga
     8401 attaacgcca ctccgtacat gatagcgtcc ggtcaagaac tccgccctcg tcggggatga
     8461 caccggacag acataaaaat tctccaagat cgttccctca tgagcgatac gatctatatt
     8521 aggagtttgc acgaaggtat tccccgtgaa gcccaaatcg ccccaacctt ggtcatccga
     8581 taacattacg atgatattgg ggagctgttt ttgagcgaag gccggaatac aaccggcccc
     8641 cactcccaaa acactaaaca atacgcctaa ctttgtcatt cgattcaact ttttgcctaa
     8701 tcaagattac ctttattgcg gacggctata tccttgatcc aacaatttct tcaacaacgc
     8761 ggaaagctca ttcgcaatgc ctttctcacg caagaagaga ttattactct ccaaagaatc
     8821 ggtccgcata ttataaagtt ggcctttcgg tccattcttc accggggata aacgggcggg
     8881 agccgtaaaa ccaccggagc ccagacaatc gatatatttc caatctccct tcttgatcgc
     8941 taatttgccg gagccggaca agtacatgat ctggtctctc gtcgaggcat tcatatcacc
     9001 atccaatact ttcttaaagc taaagctatc ctctgcctgt cctttaggaa gggattgccc
     9061 ggtcaaatcc gccaatgtag ccaatatatc taccaagcca accgtttggg aacaaacccc
     9121 ggggtacttg atatgatccg gccaatgaac aatcagcgga acatgatgac cgccgtccca
     9181 cgcatcacct ttctgcccac ggcggctcca gttactttga tgcccgtatt gctggatatc
     9241 ctcctcttcc catgcgcctc cgttatcact ggcgaaaatg acaatcgtat tcttctccag
     9301 acctaattcc tttagtttgg cattcacccg agccacgaca ttatcgatat cgcccataaa
     9361 atcgccatag gtacctaact cggtagatcc cttaaactga acggtgggca accatggggt
     9421 atgcggaccg gttaacggca tatataaaaa gaatggcttg tcctttcgtc cttcccgatc
     9481 gataaaagcg ataccctcat ctacgattgt cgggaaacat tcctcaaact taaaggagcg
     9541 cgacatctct ccgttacgcc accaaacgcc ccgttcccaa taaatatcat tctcgttcgt
     9601 atgtttacga tcccaagcgt aaaccgtctc atcctgtttc ttcggataag cgtccgccgt
     9661 caagatgaca tccgggtcca cgacacggtc attacgcacg aacgcataag gcggcatatc
     9721 caaagaagcc ggaaggatga aagaatagtc aaaccctaat tccgtagggc ctctttttac
     9781 aggggcggag aaatccgtat tcgtataacc aaatttctta ggggtaagaa tctgtggttt
     9841 cgagtcatct ttcaactgcc agtcgagccc tagatgccat ttcccgacac aagcggtcgt
     9901 atagccggca ttacgcatca aggaaccgat cgtcaaacgc tctggttcga tatatggaga
     9961 caagtacccc caatactcgg acttcttcgg cgtacggaaa aaataacgtc ctgtcactaa
    10021 accgtagcgt gaaggcccac tcaacgcacc cgcagaatgg gcatccgtaa aacggatacc
    10081 gttccgggcc aattgatcga tggccggtgt acgtacccta gcatatggat tattgcatcc
    10141 aacatccccg taacccatat catccgccaa aatgatcacg acattgggtt gcttttgggc
    10201 gaacaccacc ggcacatata gtaaaccggt ggctaataaa gacaacttga tcttcatata
    10261 ttattttcta ttcgttaata accttgattc tgagtcaggt tcggattcgc ctgccgttcg
    10321 cttaatggaa tcgggaacaa tagctgggtt tccgtataca ccttacccca attcgtctta
    10381 tagccgataa agtccacata ttccccggat ttatcatccc ggatcttacg ggtgcgtagc
    10441 atatcaaacc acatcttatt ctcataacat aggtcaaagt aacgttggtc ccagacttcc
    10501 tccaagaatg cgcttgcgtt ggtctgctta aacggcgcta atccggccct tcctcgtatt
    10561 tggttcacga tatcgatgga ttgctggttc ggagtaccat ccgcattcac ttgcgcttcc
    10621 gcatacatta ataatacatc cgtgtaacga tatacactcc agttcaagtc tgacttcgcc
    10681 gtattatcaa tagccacttg atcaaaaaac ttatagatat aatagccatt caaatccata
    10741 aactccaact ctgccgctcc cggagagaac ttactcggat gccccttgta gtttgtaaag
    10801 aaatattgct tctcttccgt acgcttatct cctttctcaa agctttccac gaattctttg
    10861 gtagggatca ggctaccata ttccaaatcg taggcggaaa tgccggaacg agaaggtaaa
    10921 aagatacgta ccgactcgtt atgccgcttg ttcaaggaga actgaacttg ataaataaac
    10981 tctcccttat tattctgcga cggaagccgt aggctctcat aatccgtgaa gagcgtatac
    11041 tcattcgatt ttataacctc caatgaacgt ttagccgatt ccgcgtaata agatttacct
    11101 ccttgcaaag gataaccggc atacgtaaga tagacatccg caagaagcgc tttcaccgct
    11161 cccatcgaga cacgccctgt atgatcgcta aaagccagat ccgattgctc ggcctccaac
    11221 aaatccggaa taatgatctc atcatagatt tcctttaccg gggcacgaga tacttgcagc
    11281 tctcccaact ccgactgtac ggtcgtaatc ttagggacat caccaaagat acgtaccaaa
    11341 tagaaataat acaaagccct cataaacttc acctcggcca tgtagccatt aaccaaggaa
    11401 gcatccagat tctcgaactc cccgagtttt tgaagcgcaa ggttacagtt cgctatacct
    11461 gcataacaat cttgccacca gtcctcgata tataaagaac gatcactcac cagtagatcc
    11521 tgaaagtcct tataattcga ttgggaattc tcggaagtag ctttgccagt catatattcg
    11581 agcaataaga tcgtattaca tccccaaccc ggggtcatct tattaaagac cgtattcttc
    11641 aaataagccg aattcgtcaa ggccaaagcg gactccttac ttgtcaactt tgaatcggta
    11701 gtcattgtac cggtaggctg ctcgtccaag aaattattac aagaagacaa gaataacgca
    11761 cataatgaga cgatatagat tttatttatt ttcataactc aatcgcatta gaatttaaca
    11821 tttaaaccga aagtaaaagt acgtgcttta ggctcgctga agtcgtcgat accttgtccg
    11881 aaagcagcat cctcataggt cgtaacctcc ggatcatagc ctttgtactt cgtaatacag
    11941 aacaagttct gagcactcgc gtagattctc aaatcctgta actttatctt ctggagcaag
    12001 ctcttgctga aagtatatcc caagacgaag ttctgccccc gaacgaaaga accgttctgc
    12061 atccaatgtg aatccggata agaatcatag tacgatttca tcggacgacg ctgggcaacc
    12121 atcgtatgct ggttttgcgg agtccaagcg ttcaaattcg acttgaagcc attcgctaca
    12181 cccgaccggt cttcagcatt atgagtagcg caattcacga catcattccc gaacacgaag
    12241 cggagatcga acgagaaatc gaagttctta taaagaaacg tattagagat cgtcatggtc
    12301 cagtccgggg aggtacagcc gataatcgta ttatcctcgc tattgatctt cccgtcgcca
    12361 ttcaagtcct catacttcac gtctcccgga aggcggttgt atttagccgc ttcagcggcc
    12421 tcgtcctccc cccaagttcc cagacgacgc aatccccata gcgaaccaac aggttcaccg
    12481 acacgcagga tcagcatatc cccttgcgca tggcggggtt tcggataaat atcctcatca
    12541 ttctcgccta agttcaatat cttattacgg tttacgttaa ataatactgt agacatccag
    12601 ttgaaattat ccgtttggat attatgcgta tttaaggtca actcaaaacc ttggttctgc
    12661 acggagccga tgttccgcat gatcgtattc aatccagaag ttcccgggat cggggcctcc
    12721 aataataagt cgctcgtctt tttataataa taatccaaag acagatcgat acgctgattc
    12781 aatacactca catcgacacc ggcatcccat tgcaaggtct tctcccattt caagtccggg
    12841 ttaccgaacg tactgcggta tagagccgta taatagtcat taccaaaaat ggtattctcc
    12901 gagcctagct tctggtagaa agcgtaattg ccgatctctt ggtttccggt ctcgccgata
    12961 ctagtacgta cctttaaatt attcagccaa ttgacacctt tcaagatgct ttcctccgag
    13021 gctctccacg caaaggcgaa agaggggaag aatgcgtatt tattattctt tccgaatttg
    13081 gacgatccgt cgtaacggcc tgtggccgta aatagatagc ggtctttcaa ggtataattg
    13141 atacgcgcga aataagagtt gatagaccaa ccgtaatctt ccgatttcga cggaatcgtc
    13201 accgttcccg ctcccagatt atgccattgg taaaaatcat cgctgaaatt ctgcgaggta
    13261 gcttccacgc tttcggcaac tcgctgctgc cagcttaatc caagcatcac attcatgcga
    13321 ttgtttttat taaactcctt attataatta aagtagttct cattctgcca atacatttcc
    13381 ttcaaagtct ctatcgtagc gatacctccc gccgtcttac tgaactggat cagatcctta
    13441 cccgaataat aattacgttt cctattactg gcatctacgg cgaaagtaga cttaaagttc
    13501 aagtcgtccg tgatcttgaa atccagatat aggtcggcga tcgtctggat attggaagtc
    13561 tcgttcacca tctcttccag ataccgggaa ggtgtatcct gtaccgcacc ggggaaatca
    13621 cggttgcttc cccaagagcc atcgggatat tttacgggaa tcaacggaat tgcttcctgt
    13681 accaaacgct ttactccata acttttgtaa ttatcgtttc ccttattata attgaacgac
    13741 atattggcac ccattttcaa ccaatcccga agctgggaat ccaagttgat cctaccgcta
    13801 taccggtcta ggaaaccgtt acgcatcaag gcatccttat gcatatatcc caaatgcacg
    13861 ctatacaagg tcttatcggc tccgccccgg atgctgactt ggtgattatg gttgatagcc
    13921 gtttgataag cctcatcctg ccaatcggta tcatacaatg ggttaccatt agcatcgaac
    13981 aaattcggca gatccgccgg cgtcactttc ttgtacttgc cttgcgcata cccttccgga
    14041 tcatatttct gcccgttatc catcgtggta ttgtaattct gccaccactc ggaagcgttc
    14101 atcaagtcca gtttcttcgc catcttaccg atagagacat aaccgtcgta cgagatctgc
    14161 gctttctcgt tcttgatacc tcgtttcgtc gtaatcatga tcacgccatt cgctccacgg
    14221 gcaccataga tagccgtggc ggaggcatcc ttcaatacct ccaaggattc gatctcacta
    14281 ggattcaaca gattgatatt gcttacgcca atcacgccat ctaccacata cagaggctca
    14341 ttcgatgagt tgatagagtt attaccacgg atacgcaccc gtactttccc atccggagta
    14401 ccgccattct caaagatctc cacaccggaa gcctttcccg ccaaggcctg cccaacattc
    14461 accaccggct tgctcaacag cttctccgcc tttacgttgg taaccgatcc ggtcaagtcg
    14521 ctcttcttca tcgttccgta acctacgact accacctcat ccaatgtctg tgtattctcg
    14581 cccagcttga tagagaaact cgtctttccg ttcgccgaga cctcttgcgt attatagccg
    14641 atataggaaa cttgaaggac agagttgtca tttacctcta gcgtaaactt tccgtcgaga
    14701 tcggtaatcg taccgttggt agttcctttc tccaccacgt tcgccccgat cacaggatcg
    14761 ccgttcgtat cgacaatcac acccgatact tgctttttcc ccttgacagt cttgacctct
    14821 tccggcacga tgatcacata attcccgttt attttatacg tgtatcccgt attctttaac
    14881 agctgtgata agacctgcaa tacttccatg tctttctgat ccatcgagac ctttctcgac
    14941 acgtccaatt ggctatcatt ataagctatc ttataagcag agctcgactc tagtttctca
    15001 aacgcctgtt tcaatgagat cgaaccttca tggaaggtca ctttctgcgc atcgataggc
    15061 aagctcccag ccatagcgag gctcaggcaa agaatagcga cacgtataga tttattcctg
    15121 ttcatgcgat attagatttt ttagttaaac atttatatct cctttgtagt acgtactcgc
    15181 tattaggaca agggaaacga ggagcgcacc caacggaaaa acgttaacga attataaaaa
    15241 cctaatatct ccttaactca atcaatatag atcccatcct ctttgatctg atactccaag
    15301 ccgggtatca tctccttgac caacatcatg atgttctcca acgactcatg cttattgaaa
    15361 tggatcgtaa gccggttgga atgataagcg gaagtacgca aatgcacctt cacgttgtag
    15421 acacgttcca aggttttcaa gatttcctcg aaagagtcgt tgttaaacaa caagcctccc
    15481 tctttccaat ccgagtaatc cgaggccacc acctgccgca cgtccatctt tccccgggaa
    15541 gggatgtaga caagctgctc gttaggcctc aatatacatg gagccaccga gggatcatcg
    15601 ggaagaatct tcaaggaacc ttcctccaag gtcgttgtta ttttctcttg gcccgggtag
    15661 gcggataaat tgaactcggt gcccagcact tgtacccgca tcgctttcgt ccgcacgatg
    15721 aaaggttgct cggggcgttt tcgcaccttg aaatatccct ctcccaccag atagatctcc
    15781 cggctctgac cgataaaggc ggatggatag agcagcaagg taccggaatt caaccaaacc
    15841 tcgctaccat cgggcaaggt gatccgctcc cgcttgccgg aaggtacgaa ctgttccata
    15901 aaagccagtt tcttgacatc ccgcgcatcc ctgtatagat aataagaaac acccaacgac
    15961 aacaaaggaa tcagccagat agcggcgata cgtacccacg ccgggatacg cagacggcgg
    16021 cggggcctca cgcccaatgt attctccaac cgggcgaaag ccatctcgct tcgtttatcc
    16081 gcctccggaa aaccgatctc attccagata tcccgtaaag cctcttcctt ttcccgctcg
    16141 tctcccggct ccgccaatcg ctgatgtacc cgatccacca tctccccgga gaacgaatga
    16201 tggaaaaagt attttaatat cttttttata ggactcattc ctgcttttct attttatctt
    16261 gt
//
LOCUS       DBMDTB010000090        16155 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_1152_length_16155_cov_10.882148, whole genome shotgun
            sequence.
ACCESSION   DBMDTB010000090 DBMDTB010000000
VERSION     DBMDTB010000090.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 16155)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 16155)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16155
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1152_length_16155_cov_10.882148"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..527)
                     /locus_tag="ACZPB4_13140"
     CDS             complement(<1..527)
                     /locus_tag="ACZPB4_13140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HIR1099194.1"
                     /translation="MKQLTIEAFKAMLDNALKQIKAREEEFSKLDAVIGDGDHGTAIV
                     AAMTAVNKSAQSGTEFKQMLGDMGMDVMMEVSGSTSTLLGAFFLGMSDHAEGTELDAA
                     GVKVMFAGGLANVQQQTQAKRGDKTMMDALIPAVEAMQACTSDDIKEVLNAGAKAALD
                     GAEATVPMKANFGRAR"
     gene            complement(537..1553)
                     /locus_tag="ACZPB4_13145"
     CDS             complement(537..1553)
                     /locus_tag="ACZPB4_13145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005638301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HIR1099195.1"
                     /translation="MSDIKTKFINDPENITAELLEGYVLAYPNQVKLAAENIVVRANP
                     KGNDKVAIVTLGGSGHEPALSGFVGEGMLDCSVVGDVFAAPGAQRLFQALQLMDREAG
                     ILLVVLNHSGDVMSANMACQLAARKGIKVKKLLTHDDISAGIGANVDDRRGLAGCVPL
                     YKILGAAAEEGKSLDELIEIGERYNKNVATLAVAMRSCTHPQNGGTITNLPDGIMEIG
                     MGQHGEGGGGQKPLVSADDTAAEMVDLLCQQLQPKAGDKMLLIINGVGATTHMELNII
                     FRKAYKELEARGLQVVASRIQEILTVQEQAGFQMIMAILDEDHIDYLNNKRADAPYWT
                     TLGK"
     gene            complement(1595..1909)
                     /locus_tag="ACZPB4_13150"
     CDS             complement(1595..1909)
                     /locus_tag="ACZPB4_13150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099196.1"
                     /translation="MRTFNHVGIVTTESKEGAVYNEGLSVWLTDYSKSPNRIEFLKFE
                     KGSCLPELVQTNGHIAYTVPCLEKELEGKKVIFGPAVCDEHLTIAFIEEEGIAIEIME
                     LK"
     gene            complement(1928..4375)
                     /locus_tag="ACZPB4_13155"
     CDS             complement(1928..4375)
                     /locus_tag="ACZPB4_13155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c biogenesis protein"
                     /protein_id="HIR1099197.1"
                     /translation="MKTLERFISSSVTTIVLLLIYAFGLAIATFIEKYHGTAVAKALI
                     YYSPVFFLLQFLLVANFVAIVIKHQLLKRRKWGLMVTHAAFIVILLGALISHLFGEEG
                     ILHLREGEASDRIMIRTSDQTLYHTLPFSVELVKFTLTRYPGSASPSAYESELLVHVD
                     GQTRHTRVYMNNVLDVKGYRFFQASYDPDEQGTVLSVNRDVAGRNITYTGYVILVIGF
                     ILCLVGKNSRFMKLSRQLKDLRGGARKTTLLVAVLLSVGGLRAQGAAAPEMKEVIQKY
                     AISPEHAAKFGALPIQSVSGRMLPINTFSSEVLRKLHKSDQFGSLNSDQFLLSVLAMP
                     DMWVRVPFIALSNSELANYYDLTDKECAYIEVFDSHGRYKLQEKLEEAYNKMPAERTR
                     FDKDLIKLDEQVNIFHQLINYQMLNLFPKEDDPDHKWYAPGDDLSAFSGKDSMFVTHI
                     MGWYLSEVQEGLKSGDWEKADEVIGMIHTYQQAKNKTVDIRPEKIQAEIKYNQMDVFR
                     QCKKGYLILGGLLLIFAFVVLFKKKKWVTYTTWLLSLGILAVFVFHMYGMGMRWYIAG
                     YAPWSNSYETMVYVAWATVFAGLLFVRKSTLTFALATLFGGIILFVSGLSWMDPQINP
                     LVPVLKSPWLMFHVAVIVGAYGFFGISCLIGLTNLVMMSVSGEKNSVMLKERVRELSI
                     VNEMSLWIGLALMTIGTFLGAVWANESWGRYWGWDPKETWALITMVIYAIVTHLRLIP
                     KCNNLWLFNFTSILAFYSVLMTFFGVNYFLSGMHSYGQNDNVNGIFIYLYLSIILVLG
                     AGFISYRKRTNFNNIIV"
     gene            complement(4492..8496)
                     /locus_tag="ACZPB4_13160"
     CDS             complement(4492..8496)
                     /locus_tag="ACZPB4_13160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUMF1/EgtB/PvdO family nonheme iron enzyme"
                     /protein_id="HIR1099198.1"
                     /translation="MNKYYIMVSLLLSTSLLVSAGPKQKKVDNWIDASVKQKSELRAS
                     LVKANMPIMSAWIKAKQKAVPMSADLTGQDQLVLVTAAGPDGTDWDWGTWANARLIKA
                     DGSSVWLDELDPDYWVSGSNSIRKNTDLYGNPLLIGGKKYDHSVLCHANGVMVYNINK
                     EYVRFEAEVGLADQSTVGSVFFRIMNVFPKEEAARLLAAYPKELGALNANIDGLENWL
                     TTSDASAERDIVLNLASRLKDAAYVKNAVKLIETEKDIDTQIREYLKLYEKTQRICNL
                     QSDLSWLNMEAIRLAFNDMKKLKGFDATKYQPVLDELEQQVKKGFDGIYSGDEAALVN
                     AEKAIANKRTILLANPFLDGDKVLAARFKLGVNAHKAMAPDLGTQGNNWSNQESARRM
                     GFDADIVELSNLRGEDVQVRSIYKPENGSSIADLRMHWDGDRAMFTQTMPDKRWNVFE
                     VKLDGSGFKQLIHNEEPDLEFYDGTYLPDGRIIANSNIGYQGVPCVSGDDPVGNMVLY
                     TPDTKNLRRLTFDQDANWNPVVMNNGRVMYTRWEYTDLTHYYSRIVMNMNPDGTEQKA
                     LYGSGSMFPNSTFDIQPLPGHGSAFVGIISGHHGIARSGRLIVFDPAKARKGAAGMVQ
                     EIPYRNRPIVEEIKDELVNGVWPQFIKPTPLNDKYFLVAAKLDPQDLWGIYLVDVFDN
                     VTCLRKVEGEGYISPVAVRKIQTPPAIPDRVKLNDKEATVFIQDIYEGEGLRGIPRGT
                     VKSLRLHAYEYAYVKTTSDHNWHGIQSGWDIKRMLGTVPVEEDGSAIFKIPANTPISI
                     QPLDKDGVAIQWMRSWLTGQPGEVVSCIGCHEDQNQIPIPKRVMASQKAPHALTPPEG
                     GTRSFTFDLEIQPILDRACIACHNGEGKAFDLRGGKKDKLGYGTSYLNLHPYVHRQGG
                     EGDMVVLQPYEYHPNTSELVRMLKKGHFNVQLTDKEWKTLYNWIDYNAPDKGYFNANV
                     LSKDIIPYQGFDQIKRRKELTDKYANGAGVDWKKEISDYAAYLKGKGEIKPEMPEKLA
                     PVKEKELKVKGWPFDADRIKAMLADEKETRKEIELAPGIKMTFVRIPAGQFVMGSYRG
                     QSDTRPTAKVKIDKAFWMGELEVTNQQFNVIFPDHDSRFVDQQWKDHVVQGYPANKPE
                     QPVIRVSYNDAMDYCKKLSEKTGLNITLPTEAQWEWACRAGSDQDFWYGDMNADFGKK
                     DNLADVTTLLLAVSGIDPQPMPKTSYWYKYYTYLPKEEGVDDGNLVQVGGKQYEANPF
                     GLYCMHGNVAEWTRSDYLPYPYNEKSKEVSEYKVVRGGSYIERPKFSTAYTRKGYYPY
                     QRVFNVGFRVIIED"
     gene            complement(8589..9347)
                     /locus_tag="ACZPB4_13165"
     CDS             complement(8589..9347)
                     /locus_tag="ACZPB4_13165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HIR1099199.1"
                     /translation="MRKGLNMKMAAMGLALASMVACTGKTTTDATCCAANGEGNCPEG
                     TCRKECTNACNTNNQKNKTMAYSKKYTNADFYKDGKFQQDVAMEAMKDMFAFYDVPFT
                     ELMAKDMWVTDFGLGDFENVGMGGIFWINDPEYKYFAHAIYLLPGQMIPEHAHVKTDF
                     PAKHESWMVEKGWVYNFSEVGDETPNAPAIPAGHGPIKSKNFVVQKVGDVLRLKKLET
                     FHFMMAGPEGAIVDEWACYHDNAGLRFTNQKAAL"
     gene            complement(9382..10476)
                     /locus_tag="ACZPB4_13170"
     CDS             complement(9382..10476)
                     /locus_tag="ACZPB4_13170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate transformation FkbO/Hyg5 family
                     protein"
                     /protein_id="HIR1099200.1"
                     /translation="MNYCEKIHYTILNTEPAEFAVMVDDLLSQLPQNEVIMRLAFFGT
                     PGTNEEYVARRVLLREKIRRYYGDCEPALSYVSQPPLNAPLLMEVHSYVPDAQDRITF
                     RHYQGVPYVLLENASGRFLFAGGFQGDVLHFGIEPQSVEAFRLLGDVLRWEGFPLNSI
                     IRQWNYIERITAFDGQDQHYQAFNNARSDFYSKTEWTNGYPAATGIGANLGGILIDVD
                     AVVFTTPDAFATPIDNKLQVAAHAYSEQVLEVARQKKTTPKFERAKSMSFQDRKLIYI
                     SGTAAIRGEESLKGVGLERQLRITMENIAELIADAKLVKLRVYLKNKSDYEEAERLMN
                     TYGLNIPISYMWADVCRDELLIEIEGIAIR"
     gene            complement(10488..12263)
                     /locus_tag="ACZPB4_13175"
     CDS             complement(10488..12263)
                     /locus_tag="ACZPB4_13175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YVTN family beta-propeller repeat-containing
                     protein"
                     /protein_id="HIR1099201.1"
                     /translation="MNTRKYLIKNSLVACLVGCCVSLASAGNPPFFTTDAVLNAKGEL
                     LMTQKGTRHLDIFSADGKSLLHSFPFDEIPTGLLPDGDKVYVTTFEKTGRLQVLSLES
                     GRVESAIPTGSGACHPMFGPDKKHIYVCNQFDNSVVEVDPVMRKVVRSVKVLREPKSA
                     VFSKDGKYMFVTNFLPSQRADVDVVAACVSVIEMDGFTKVKDIQLANGSNALRGMCIT
                     PDGKYIYVSHNLGRFTVPTSQLQQGWMNTSAFSVIDVAKQEFVGAVLVDEPDRGAAGI
                     WSIACDDKHIFITHSGTHEVSVIDHPAMLAKFESYKDKSRLDYDLNFLYGLRERVPLQ
                     GNGPRNFIFSGDKLIIPTYFADILNTVDINTLEVTATDMNPGRTETPENKGEKYFNDA
                     NHCYQGWQSCNGCHPGDARTDGMNWDLMNDGVGNSKNCKSMLYSHVTPPSMISGVRES
                     AEYAVRAGFKFIQFFEPEEEMAKCVDAYMKSLRPVPSPYLVNGELSDKAKEGRKVFEK
                     LKCGECHSGPYYTDMKMHRIGEDIEFEKGWDTPTLIEVWRTAPYLFDGRAATMEEVFE
                     VHKHGIDKKVSKKDVEALTEYVNSL"
     gene            complement(12281..13078)
                     /locus_tag="ACZPB4_13180"
     CDS             complement(12281..13078)
                     /locus_tag="ACZPB4_13180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HIR1099202.1"
                     /translation="MENTLPNMEKVDENYKVPNLEKGIAVLEYLSLRSAGETLQDIKS
                     ALDISQTTAYRILNTLVRLEYLNFSEDTKRYKLSRKLLTLGFRSLNEHNLLETVLPHL
                     RDLRDQVKETACFGVLGDEKGIFIEQAQGHHTFRFVLSPGKPFELHCSAPGKAIMAYL
                     PKTVRDRYLSYMTFTRYNSRTITSREAYLEELEKVGKLGYAMDNEEELSGVICVGAPI
                     FNYTGYPCGAIWISGPKDRLSKEVVKNTVKAIKEVAGVISNELGFRK"
     gene            complement(13244..13732)
                     /locus_tag="ACZPB4_13185"
     CDS             complement(13244..13732)
                     /locus_tag="ACZPB4_13185"
                     /EC_number="1.16.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007658513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008199 - ferric iron binding [Evidence
                     IEA];
                     GO_function: GO:0016722 - oxidoreductase activity, acting
                     on metal ions [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Dps family protein"
                     /protein_id="HIR1099203.1"
                     /translation="MKTLDYLHLDASAVSNVVASLKQLLADYQVFYTNLRGFHWNIKG
                     HGFFVLHGKFEDMYNNAAEKVDELAERILMLGGEPENKFSEYLKVARVKEVSGVSCGD
                     EALKNILDTYGHLIGEERKLLSLASEAGDEATVALMSDYLKEQEKLVWMLVAYSTCDC
                     KK"
     gene            complement(13887..14570)
                     /locus_tag="ACZPB4_13190"
     CDS             complement(13887..14570)
                     /locus_tag="ACZPB4_13190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane beta-barrel protein"
                     /protein_id="HIR1099204.1"
                     /translation="MKRVVLFAMVLMLGVISVQAQWSVVPEAGMTVMKAGPIVDWKPS
                     WKIGVGVEYQLKPEFLSLKSGLYYTQRGYSNDKFPGYGYGCYWWAVPGPTYDPYGYAY
                     DYSNKVTRNFLQLPIMANFSFKLAEDIRLNVGVGPYIAVSVLDKGMFGGWSVASEESA
                     KFYTHDPCEGLRAFDWGISATVGVEIKQCFINFGYDVSLGKEYKGGSIEANYHTLALT
                     AGYKFKLGK"
     gene            complement(14706..15194)
                     /locus_tag="ACZPB4_13195"
     CDS             complement(14706..15194)
                     /locus_tag="ACZPB4_13195"
                     /EC_number="1.16.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007658513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008199 - ferric iron binding [Evidence
                     IEA];
                     GO_function: GO:0016722 - oxidoreductase activity, acting
                     on metal ions [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Dps family protein"
                     /protein_id="HIR1099205.1"
                     /translation="MRTLDYIHLDASAVSNVVASLKQLLADYQVFYTNLRGFHWNIKG
                     HGFFVLHGKFEDMYNNAAEKVDELAERILMLGGEPENKFSEYLKVARVKEVSGVSCGD
                     EALKNILDTYGHLIDEERKLLSLASGAGDEATVALMSDYLKEQEKLVWMLVAYSTCDC
                     KK"
     gene            15830..>16155
                     /locus_tag="ACZPB4_13200"
     CDS             15830..>16155
                     /locus_tag="ACZPB4_13200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099206.1"
                     /translation="MEVQELLKLYAAHPQVTALDTLLKNDTSRNIFLKGLNGSGPAMT
                     IASLFTKGRGSYVCVLNDQEEAGYFYHDLMQLTASNEVYFFPSAYRRAIKYGHVDPAN
                     EILRTEV"
BASE COUNT         4436 a         4393 c         3083 g         4243 t
ORIGIN      
        1 cgggcacgtc caaagttagc tttcatcggt accgtagcct ccgctccatc aagcgccgct
       61 ttagcgccgg cattcaagac ctccttgata tcatccgacg tacaagcctg catagcctcc
      121 accgccggga tcaaggcatc catcatcgtc ttgtcgcctc gtttcgcttg ggtttgttgt
      181 tgcacattcg ccaagccacc ggcgaacata actttcacgc ctgcggcatc caactcggtt
      241 ccctctgcat gatcgctcat acccaagaag aaagcaccga gcaaggtact tgtcgatcca
      301 ctcacttcca tcatcacatc catacccata tcaccaagca tttgcttgaa ctccgttcca
      361 gactgagcgc ttttattcac agcagtcata gcggcaacga tagcggtacc atgatcacca
      421 tccccgatta cggcatccaa tttagagaat tcctcctcac gtgccttgat ctgtttcagc
      481 gcattgtcta acatggcctt gaaggcctcg atagtaagtt gtttcatgta tattatttat
      541 ttacctaggg ttgtccaata aggtgcgtcc gcacgtttgt tattcaaata atcgatatga
      601 tcctcatcca agatcgccat aatcatctgg aatccggctt gctcctgtac ggtcaagatc
      661 tcttggatac ggcttgccac cacctgcaag ccgcgagcct ctaattcctt ataagccttg
      721 cggaagatga tattcaattc catatgggta gtagcgccta cgccgttaat gatcagcaac
      781 atcttatcgc cggcttttgg ctgtaactgc tggcaaagca ggtctaccat ctccgcagcc
      841 gtatcatcgg cggataccaa cggtttctgt ccaccgccac cttcgccatg ttggcccata
      901 ccgatctcca tgataccatc gggaaggttc gtgatcgtac ctccgttctg gggatgagta
      961 caagaccgca tagcgacagc caaggtagcc acgttcttat tatagcgttc accaatctca
     1021 atcagctcgt ctaaagactt cccttcctca gcggcggcac ctaatatctt atacaaagga
     1081 acacaaccgg ccaagccgcg gcgatcgtct acattcgccc cgatacctgc gctgatatca
     1141 tcatgcgtaa gtaatttctt caccttgatc cctttacgag cagccaactg gcaagccatg
     1201 ttagcgctca tcacgtcgcc ggaatggttc aatacgacca acaagatccc ggcctcacga
     1261 tccatcaatt gcagtgcctg aaacaaacgt tgggcacccg gagcggcgaa tacgtcaccc
     1321 acgacggagc aatccaacat gccctctcct acgaaaccgc tcaaggcagg ctcatgaccg
     1381 gaaccgccta aggtaacgat cgcaacctta tcattgcctt tcgggttagc acgtacgacg
     1441 atattctcag ccgccaactt tacctgattc ggatacgcta atacatagcc ttccaataac
     1501 tcagccgtaa tattctcagg atcatttatg aattttgtct tgatgtctga catggtatta
     1561 tcctccttta gatttataaa ttttgattta cgaattattt tagttccatg atctcgatag
     1621 cgataccttc ttcctcgatg aaagcgatcg tcaagtgctc gtcgcaaaca gctgggccga
     1681 agattacctt cttaccttcc aactcttttt ccaaacaagg aaccgtataa gcgatatggc
     1741 cattggtctg taccaactcc ggtaggcagc tgcctttctc gaatttcaag aactcgatcc
     1801 ggttcggact cttgctgtaa tccgtcaacc atacactcag gccttcgtta taaaccgccc
     1861 cttctttact ttccgtagtg acaattccta cgtgattaaa tgttctcatg atctattcaa
     1921 tttatagtta gacaattata ttattaaaat tcgttctctt ccgataggat ataaagccag
     1981 cccccaatac taggatgatc gacagataaa gataaataaa tatcccgttc acgttgtcat
     2041 tctggccata agagtgcatg ccactcaaga aataattcac gccgaagaag gtcatcaaca
     2101 ccgaatagaa ggccaagata gacgtaaaat taaacaacca caggttattg catttcggta
     2161 tcaagcggag atgcgtcacg atcgcatata tcaccatcgt aatcaacgcc cacgtctcct
     2221 tcgggtccca gccccaataa cgtccccacg actcattcgc ccagaccgct cccaagaaag
     2281 taccgatcgt catcagggcc aatccgatcc aaagtgacat ctcgttcacg atactcaatt
     2341 ctcgtacccg ttctttgagc atcacgctgt tcttctcccc gcttacgctc atcatcacca
     2401 gattcgtcaa gccgatcaga caactaatac cgaagaaacc ataagctccc acgataaccg
     2461 ccacatggaa catcaaccat ggggatttca agaccggaac cagcggattg atctgcgggt
     2521 ccatccaact caagccggac acgaacaaga tgatcccccc gaataaagta gccaacgcaa
     2581 acgtaagcgt actcttgcgt acgaacaaca acccggcgaa caccgtagcc caagccacat
     2641 aaaccatcgt ctcgtacgaa ttgctccaag gggcgtaacc tgcgatatac caccgcattc
     2701 ccatcccata catatggaaa acgaatacgg ccaaaatgcc cagactcaat aaccaagtcg
     2761 tataggtaac ccattttttc ttcttgaata agaccacgaa agcgaagatc agcaacaagc
     2821 ctcccaaaat caagtaccct ttcttacatt gccggaatac atccatttga ttatatttaa
     2881 tctcggcctg tattttctca gggcgaatgt ctaccgtctt attcttggct tgctgatacg
     2941 tatggatcat tccgattacc tcgtccgctt tctcccaatc accactcttc aatccttcct
     3001 gtacctccga taaataccag cccataatgt gggtaacgaa catggagtcc tttccggaaa
     3061 acgccgacaa atcatcgccc ggcgcatacc atttgtgatc cggatcgtcc tctttcggga
     3121 aaaggttcaa catctggtaa ttgatcaatt gatggaagat attcacctgc tcgtccagct
     3181 tgatcaagtc tttatcgaag cgggtacgct ccgccggcat tttattgtag gcctcttcca
     3241 gcttctcttg caatttatag cgtccgtggc tatcgaatac ctctatatag gcacactcct
     3301 tatccgtaag gtcgtaataa ttggccagct cactattaga caaggcgata aacggcaccc
     3361 ggacccacat atccggcata gccaagacac tcaacaagaa ctgatccgag ttcaaggaac
     3421 cgaactgatc cgatttatgc aactttcgca gtacctcgga agagaatgta ttgatcggca
     3481 acatacgtcc gcttaccgat tggatcggca acgcaccgaa cttagcggca tgttccggac
     3541 ttatcgcata tttctgtata acctccttca tctcgggagc ggccgcacct tgcgcccgca
     3601 agccccctac ggaaagaaga accgctacta acagggtcgt tttacgagcg ccccctctta
     3661 aatctttcaa ctgacggctt aatttcatga aacgggagtt cttgcctacc aagcaaagta
     3721 taaagccgat cactaaaatc acgtagccgg tatacgtaat attccttccg gccacatctc
     3781 ggttcacgga aagtaccgtt ccttgctcat ccggatcata ggaggcttgg aagaagcgat
     3841 agcctttcac gtctaataca ttattcatat atacccgggt atggcgagtc tgtccatcta
     3901 catgtaccag caactcactc tcataagcag agggactggc agagccggga tagcgggtta
     3961 aggtaaattt cacgagttct acgctaaaag gaagcgtatg atagagagtc tggtccgagg
     4021 tacggatcat gatacgatcg ctagcctctc cctcacgcag gtgaaggatt ccttcctcgc
     4081 cgaaaaggtg ggaaataagg gcacccagaa ggatgacaat aaaggcggca tgggtgacca
     4141 tcaatcccca tttacgccgc ttaagtaact ggtgcttgat aacgatagcc acgaaattgg
     4201 ctaccaataa gaattggagt aagaaaaata caggagaata gtaaatcagc gctttagcga
     4261 cggcagtacc atgatacttc tctataaaag tagcgatagc caagccaaag gcgtagatca
     4321 atagaaggac gatagtcgtc acggaagaag agataaatct ttctagagtt ttcatttgct
     4381 catttattaa taacactgat gcgacaaatg tacgcagatt aatcattttt gaaagaatcg
     4441 gcgattaatt tgccgcatcc atgttatcta tctataaata gaccttgtct attaatcctc
     4501 aataattacc cggaagccta cgttgaacac acgttggtac ggataatatc ctttacgggt
     4561 ataagccgtc gagaatttcg gtcgctcgat ataagaaccg ccacgaacca ccttatactc
     4621 ggagacctct ttcgatttct cgttgtaagg ataaggcaag taatcagaac gagtccattc
     4681 cgccacgtta ccgtgcatgc aatacaaacc gaacggattc gcttcatatt gcttaccacc
     4741 cacctgaacc aaattgccat catccacgcc ttcctctttc ggtaagtaag tatagtattt
     4801 gtaccaataa gaagtcttag gcatcggttg cgggtcgata ccgcttacgg caagcaggag
     4861 cgtggttacg tcggctaggt tatccttttt gccgaagtcc gcattcatat cgccatacca
     4921 gaaatcttga tcgctaccgg cacgacaagc ccattcccat tgcgcctcgg tcggaagcgt
     4981 gatgttcaag cctgttttct cactcagctt cttacaataa tccatagcgt cattgtaact
     5041 tacacggatt accggttgct ccggtttatt agcgggatat ccttgaacca cgtgatcttt
     5101 ccattgctga tccacgaaac ggctgtcgtg atccgggaaa atcacgttga attgctggtt
     5161 cgtaacctcc aactcaccca tccagaaagc tttgtcaatc ttcactttcg ccgtcggacg
     5221 agtatcggat tgcccacgat agctgcccat cacgaattgt ccggccggaa tgcgaacaaa
     5281 tgtcatcttg atacccggag ccaactcgat ctccttacgg gtttccttct cgtcagccaa
     5341 catagccttg atccggtccg catcgaaagg ccagcctttc accttcaact ctttttcctt
     5401 gacaggagcc aatttctccg gcatctccgg tttgatctca cctttaccct tcaagtaagc
     5461 ggcataatcg gagatctctt tcttccaatc cacgcctgcg ccattcgcat acttatccgt
     5521 caactcttta cgacgcttga tctggtcgaa gccttgatac gggatgatat ccttcgaaag
     5581 cacattcgca ttgaaataac ccttatccgg agcgttgtaa tcaatccagt tataaagggt
     5641 tttccactct ttatccgtca gttgcacgtt aaagtgccct ttcttcaaca tacgaaccag
     5701 ttcactcgtg ttcggatgat attcatacgg ttgaagaacc accatatcac cctcgccacc
     5761 ttgacggtgt acatacggat gcagattcaa gtaagaagtg ccataaccta atttatcctt
     5821 cttgccccca cgcaagtcga aagccttacc ctcaccatta tggcaagcga tacaggcacg
     5881 atccaagatc ggttggatct ccagatcgaa cgtgaacgaa cgggtccccc cttccggcgg
     5941 agtcaacgca tgcggggctt tctgcgaagc catcacacgt ttcggaatag gaatctggtt
     6001 ctggtcctca tggcaaccga tacaagatac cacctcgccc ggctgaccgg tcaaccagct
     6061 acgcatccac tggatagcca caccgtcttt gtctaacggc tggatagaaa tcggcgtatt
     6121 cgccgggatc ttgaagatag cggagccatc ctcttctacc ggtaccgtac ccaacatacg
     6181 cttgatgtcc caaccggact ggattccatg ccagttatga tcggaggtag tcttcacgta
     6241 agcatactca taagcgtgca gacgaagaga cttaaccgta ccccggggaa tgcctctcaa
     6301 accctctccc tcgtaaatat cctgaataaa gaccgtagcc tctttgtcat tcaatttcac
     6361 acggtccgga atagccggag gagtctgtat cttacgtacg gcaaccggac tgatatagcc
     6421 ctcaccctct accttacgca aacaagtcac gttatcgaag acgtccacca aatagatacc
     6481 ccataaatcc tgcgggtcta atttagcggc caccaagaaa tatttatcat tcagcggagt
     6541 cggtttgata aactgcggcc atacgccatt caccagctca tccttaatct cctccacgat
     6601 cggccggtta cgatacggga tctcctgtac cataccggcg gcgcctttac gggcttttgc
     6661 cggatcgaac acgatcaaac ggccggaacg ggcgatacca tggtgaccgg agataattcc
     6721 cacgaaagcg gaaccgtggc ccggcaacgg ctggatatca aacgtactgt tcgggaacat
     6781 cgatccgcta ccatacagcg ctttctgctc cgtaccatcc ggattcatgt tcatcacgat
     6841 acgggaataa tagtgcgtca agtccgtgta ctcccaacgg gtatacatca cacgaccgtt
     6901 attcatcact accgggttcc agttcgcgtc ttgatcgaaa gtcagacggc gcaagttctt
     6961 cgtatccggc gtataaagta ccatattacc gacagggtca tcaccgctta cacaaggcac
     7021 gccttgataa ccgatattcg agttggcgat gatacgtccg tccggtaagt aggttccatc
     7081 ataaaactcc agatccggtt cctcgttatg tattaattgc ttaaagcccg agccatccaa
     7141 tttcacctcg aatacgttcc aacgcttatc gggcatcgtc tgggtaaaca tagcacgatc
     7201 gccatcccaa tgcatccgca agtcagcgat agaggaaccg ttttccggtt tataaatcga
     7261 ccgtacctgt acatcctccc cacgtagatt actcaactcc acaatatcgg cgtcgaatcc
     7321 catacggcgg gcggactctt ggttactcca gttattaccc tgcgtaccca aatccggagc
     7381 cattgcctta tgagcgttta cacctaattt aaagcgggca gccaagactt tatcaccatc
     7441 caagaacggg ttcgccagca agatcgtacg tttattcgca atcgctttct ccgcgttaac
     7501 caaagcggcc tcatcaccac tataaatgcc atcgaaacct ttctttacct gctgttccag
     7561 ctcatccaaa accggttgat acttagtggc atcgaaacct ttcagttttt tcatatcatt
     7621 gaaagccaga cgaatcgcct ccatattcaa ccaactcaag tcgctctgca aattacagat
     7681 acgttgagtt ttctcataaa gtttcaaata ctcacggatc tgagtatcaa tatctttttc
     7741 tgtctcgatc agcttaacag cgttctttac atacgcagcg tctttcagac gagaagccag
     7801 attcaagaca atatcacgct cagcggaagc gtcactagta gtcaaccaat tctccaaccc
     7861 atcgatatta gcgtttaagg ctcctaattc cttcggataa gcggctagca agcgtgcggc
     7921 ctcctccttc gggaaaacat tcatgatacg gaagaataca ctacctaccg ttgactgatc
     7981 ggccaaaccc acctcagcct caaagcgtac atattcctta ttgatattgt acaccatcac
     8041 gccattggca tggcataata cgctatggtc gtatttctta ccaccgatca acaatggatt
     8101 cccgtataaa tccgtattct tgcggatact gttcgaaccg gaaacccaat aatccgggtc
     8161 taactcatcc aaccaaaccg aactaccgtc cgccttgatt aaacgggcat tcgcccatgt
     8221 accccaatcc caatccgtac cgtccggtcc ggcggccgta acaagtacca actgatcctg
     8281 acccgtcaaa tcggcggaca tcgggacagc cttctgcttc gctttgatcc aagcggacat
     8341 gatcggcatg ttcgccttca ccaaagaggc acgaagctca gacttttgtt ttactgaggc
     8401 gtcaatccaa ttatccacct tcttttgctt cggacctgcc gaaacaagaa gagaggtcga
     8461 caacaagagt gataccatta tatagtattt attcatgtat taaatttaaa tttagaaggt
     8521 tgtttattga aaccctaagg atcacgatcg gcaaccctta gaattacgaa gcataaccct
     8581 agaggttttt ataaagcggc cttctggttc gtgaaacgta agccagcgtt gtcgtgatag
     8641 catgcccact catctacgat agcgccttcc ggacctgcca tcataaagtg gaatgtctcc
     8701 aatttcttca gacgtaatac gtcgccgacc ttctgaacca cgaagttctt gctcttgatc
     8761 ggtccatgtc cggcggggat agccggtgcg ttcggagtct cgtcaccaac ctcagagaag
     8821 ttgtataccc aacccttctc taccatccaa gactcatgtt tagccgggaa gtcagtcttt
     8881 acgtgagcat gttccggaat catctggccc ggcaacaaat agatagcgtg agcgaaatac
     8941 ttatactccg gatcgttgat ccagaaaata ccccccatac ctacattctc gaaatcaccc
     9001 aaaccaaagt ctgtcaccca catatctttc gccatcaact ccgtgaaagg aacatcgtaa
     9061 aaagcaaaca tatctttcat cgcttccata gcgacatctt gttggaactt gccgtcttta
     9121 taaaaatcgg cgttcgtgta cttctttgaa taagccattg ttttattttt ttgattgtta
     9181 gtattacatg cgttcgtgca ttctttgcgg caagttcctt ccggacaatt gccctccccg
     9241 ttagcggcgc aacaagtagc gtctgttgtt gtctttcccg tacatgcgac catagatgcc
     9301 aacgccaatc ccatagccgc cattttcatg ttcaaacctt ttctcatttg tttttgtgta
     9361 tatttgttag tactatctgt ttcaacgtat cgctattccc tcgatctcga tcaataactc
     9421 atcccggcaa acgtcggccc acatataaga gatcgggata tttaatccgt aggtattcat
     9481 caaacgctca gcctcctcgt agtcggattt attcttcaag tagactcgta acttaaccaa
     9541 tttagcgtca gcgatcagtt ccgctatatt ttccatcgtg atccgtagct gacgttccag
     9601 acctactccc ttcaagctct cctcaccacg gatagcggct gtaccggaga tataaatcaa
     9661 tttacgatcc tgaaaagaca tactcttggc acgctcgaac ttaggggtcg tcttcttttg
     9721 tcgggcaact tccagtactt gttccgaata cgcatgggca gccacctgca acttattatc
     9781 gatcggcgta gcgaaagcgt ccggcgtagt aaatacgaca gcatccacat caatcaagat
     9841 acctcccaga ttcgccccga tacccgtagc ggcaggataa ccattcgtcc attccgtttt
     9901 actataaaaa tcagaccggg cgttattaaa cgcttgataa tgctgatcct gaccgtcgaa
     9961 agctgttata cgctcgatat aattccactg acggataatg ctattcaacg gaaaaccctc
    10021 ccaacgaagc acatccccca ataaccggaa agcttccacc gactgaggct ctataccaaa
    10081 atggagtaca tccccttgaa aaccgccggc aaaaaggaaa cgtcccgagg cattctccaa
    10141 caagacataa ggaacacctt gataatgacg gaaagtaatc cgatcctgcg catcgggcac
    10201 atagctatgt acctccatca gcaaaggagc gttcagcggc ggttgggaga catagctcaa
    10261 agccggttcg caatccccat aataccgacg gattttctcc cgcagcaaaa cccggcgtgc
    10321 cacgtattcc tcattcgtac ccggagtacc gaaaaaggcc agtctcatga tcacctcgtt
    10381 ttgaggtaat tgagacaata gatcgtccac cataaccgcg aactcagccg gctcagtgtt
    10441 taatatcgta taatgtattt tctcacaata attcatatcc ttttatttta cagggagttt
    10501 acatattccg ttaatgcctc gacatctttc ttggagacct ttttatcgat accatgctta
    10561 tggacctcga acacctcttc catggtagcc gcacgcccat caaacagata aggagccgta
    10621 cgccaaacct caatcaaagt aggagtgtcc caccctttct caaattcgat atcctcgccg
    10681 atacggtgca tcttcatatc cgtataataa ggaccgctat gacactcgcc acatttcagt
    10741 ttctcaaaca cctttcttcc ctctttcgcc ttatccgata attccccatt tactaaatac
    10801 gggctaggca ccggacgcaa ggatttcata taagcgtcca cacatttcgc catttcctct
    10861 tctggctcaa aaaactggat gaacttaaaa ccagcacgta ccgcatattc cgcactctca
    10921 cgaacacccg agatcatact tgggggagtc acatgcgaat acaacatgct cttacaattc
    10981 ttcgagttac caactccatc attcatcaag tcccagttca tcccgtccgt acgggcatcc
    11041 cccggatggc aaccattaca actctgccag ccttgataac aatgattcgc atcgttaaaa
    11101 tatttctcgc ccttgttctc cggcgtttcc gtacggcccg gattcatgtc ggtagccgtt
    11161 acctccaatg tatttatatc gacggtattc aagatatcgg cgaaataagt agggattatc
    11221 aacttatctc ccgaaaatat aaaatttcgg ggaccgtttc cttgtaaggg aactcgctca
    11281 cgaagtccat acaagaaatt caagtcgtaa tccagacggc tcttatcctt ataagactca
    11341 aacttcgcca acatcgccgg atgatcgatc acgcttacct catgcgtacc gctatgcgtg
    11401 ataaagatat gcttgtcatc gcaagcgata ctccagatac cggcagcgcc acgatccggc
    11461 tcgtccacca ataccgcccc aacgaattcc tgcttcgcca catcgatcac gctgaaagca
    11521 ctcgtgttca tccaaccttg ttgaagttgg gaagtaggta ccgtgaatcg tcccaagtta
    11581 tgagacacgt atatatattt cccatccggc gtgatacaca tcccccgtaa ggcattgcta
    11641 ccattcgcca attggatatc tttcactttc gtaaacccat ccatctcgat taccgatacg
    11701 caagcggcca ccacatctac gtccgcccgc tgcgagggca agaaattcgt gacaaacatg
    11761 tatttaccat ccttgctgaa taccgccgat ttaggctcac gcaacacttt cacgctccgg
    11821 actaccttac gcatcaccgg atctacctcg accaccgaat tatcgaactg attacataca
    11881 tatatatgtt tcttatccgg tccgaacatc ggatggcagg ctcccgatcc tgtcggtatg
    11941 gccgattcca ccctacccga ttccaaggaa agcacttgta aacggccagt cttctcgaag
    12001 gtcgtcacat acaccttatc cccatccgga agcaatccgg tcgggatctc atcaaacgga
    12061 aacgaatgaa gcaagctctt accgtccgct gaaaagatat ccagatgtct cgttcctttc
    12121 tgtgtcatta atagctcccc ctttgcgttc aatacggcat ccgtagtaaa gaaaggtggg
    12181 ttgccggctg aagcgagaga aacgcaacag ccgacaagac aagccaccaa tgagtttttt
    12241 atcaagtatt ttcgtgtgtt catggtatat tttgtattcc ttattttcta aatcctagtt
    12301 cgttcgagat taccccggca acctccttga tcgccttcac cgtatttttc accacctctt
    12361 tcgataagcg gtctttcggg ccggagatcc aaatcgctcc acaaggatat cccgtataat
    12421 taaagatcgg ggcgcctacg cagatcacgc cgctcagctc ctcctcatta tccatggcat
    12481 atcccagctt accaaccttc tccaattcct ccagataggc ctcacgagaa gtgatcgtcc
    12541 gggaattata ccgtgtaaac gtcatgtagg acaggtaacg atctcgcacc gtcttcggca
    12601 aataagccat aatcgccttt cccggagccg aacaatgcaa ctcaaacggc tttcccggcg
    12661 acaggacgaa gcggaacgta tgatgtcctt gcgcttgttc gataaaaatc cctttctcat
    12721 ctcccaagac accaaagcaa gcggtctctt tcacttgatc acgtaaatca cgcaaatgtg
    12781 gcaagacggt ctctaaaaga ttgtgttcat tcaaggatct gaaaccaaga gtcaataatt
    12841 ttcgggaaag tttatagcgt ttcgtgtctt cactaaaatt aagatattcc agccgcacca
    12901 atgtattcaa aatacggtaa gccgtggtct gcgatatatc gagcgccgac ttaatatctt
    12961 gcaatgtttc ccccgccgac cgcaaggaaa ggtactcaag aaccgcaatg cccttctcta
    13021 aattaggcac tttatagttc tcatccactt tttccatatt tggtagcgtg ttttccatat
    13081 ttgaaattgc gtttcagatt tgaatcaaat atagcagtga tgaatttaaa caagatacga
    13141 aatatgtaaa aaggtgttaa gtatgttgca gagcataaat atcatagaac aaaaaagccg
    13201 gaatctcttc cggccttctt taaacgcaat gaatctacta tttttatttc ttgcaatcgc
    13261 aagttgagta ggctactaac atccaaacca acttctcctg ttctttcaga taatcgctca
    13321 tcaaagcgac cgtagcctca tcgcctgcct cagatgccaa ggaaagaagt ttacgctcct
    13381 caccgatcag atgaccgtat gtatcaagaa tattctttaa cgcctcgtca ccacaagata
    13441 cgcctgatac ctcttttaca cgggctactt tcaaatactc gctgaacttg ttctccggct
    13501 cgcctcccaa catcaggata cgttccgcca actcgtcaac cttctcagca gcgttgttgt
    13561 acatatcctc gaatttacca tgaagaacga agaaaccgtg tcccttaata ttccagtgga
    13621 aaccacgaag gttcgtatag aatacttggt aatccgccaa taattgtttc aagcttgcta
    13681 ctacgttact taccgctgac gcgtctaaat gaagataatc taatgttttc atactgctat
    13741 tttttaattg ttatactttt cgtttttctt atatcgcaaa gatatggcaa atataaacaa
    13801 ctgtcaaaca gataattcct atacatatat agataaaatc tatatttaaa cgatcagcag
    13861 gaagacttgc gatagaactt ggggttctat ttacccaatt taaacttata tcctgcggta
    13921 agagccaaag tatggtaatt cgcctcgatc gatcctccct tatactcttt acctaacgat
    13981 acatcatagc caaaattgat aaagcattgt tttatttcca cacctacagt ggcacttatc
    14041 ccccaatcaa aagcacgaag cccttcacag ggatcatggg tataaaactt agcggattct
    14101 tccgaagcga cagaccatcc cccgaacatt cctttatcca atacgcttac ggctatataa
    14161 gggcctactc caacattcaa acgaatatcc tcagctaatt tgaatgagaa attagccata
    14221 atcggtaatt gcaagaaatt tcgtgtcacc ttatttgagt aatcatacgc atatccatac
    14281 ggatcataag taggtcccgg cactgcccac caataacacc catatccata tccgggaaat
    14341 ttgtcattac tatatcccct ttgcgtataa tacaaaccag acttcagaga gagaaattcc
    14401 ggcttcaact gatattccac tcctacccca atcttccaac tcggtttcca atcaacaatt
    14461 ggacccgcct tcatcactgt catacccgct tccggaacta ccgaccactg ggcttgtacc
    14521 gatattacac ccaacattaa caccatcgca aataatacaa ctcttttcat atacttttta
    14581 ttttgataaa ataatcgaac gacatatatg aataagacat gaaacaataa aaaaccccta
    14641 ttggcaccaa cagaaaaagg ccggaatcac ttccgacctt ctccaaacgc aatgaatcac
    14701 cttttttact tcttgcaatc gcaagttgaa tatgctacta acatccaaac caacttctct
    14761 tgttctttca gataatcgct catcaaagcg accgtagcct catctcccgc cccggatgcc
    14821 aaggaaagaa gtttacgttc ctcatcgatc aaatgaccat acgtatcaag aatattcttt
    14881 aacgcctcgt caccacagga cacgcctgat acctctttta cacgggctac tttcaggtac
    14941 tcgctgaact tgttctccgg ctcgcctccc aacatcagga tacgttccgc caactcgtca
    15001 accttctcgg cagcgttgtt gtacatatcc tcgaatttac catgaagaac gaagaaaccg
    15061 tgtcccttga tattccagtg gaaaccacga aggttcgtat agaatacttg gtagtccgcc
    15121 aataattgtt tcaagcttgc tactacgtta cttaccgctg atgcgtctaa gtggatataa
    15181 tctaatgttc tcataattgc tactttttaa tttgttatac tttttgtttt tcttataccg
    15241 caaagatacg gcaagtataa gtagctgtca aacagataat ttttatatca agatagagga
    15301 aatttattaa actattccat acaataagta tgcaaatgac atgaatacat aaataattgg
    15361 atactaacat tttaaaaaga cgattatcat tttcgaaaaa cacgtacgtg tttttttgaa
    15421 aagtcgtaca tgtttttcgg gaaacacgta cgacttttta cagaatcata cggcaaggaa
    15481 ctagaacata cataaaaata tacgataagt ctcccttttt cagggggccc aaaagcattt
    15541 cccccaaaat cccctactcg aatcctcact gtggttttag agagccgtaa aagaatgaag
    15601 ccggcgcctc cgtctatcag aaaatttctt gcgcagagga tggcaaagat agatgagtcc
    15661 gttctatagc cacttagcaa atttacagat tctcttacca catttacgga tttaccaata
    15721 tcaatagtcg tctttatcaa ggattagtta cttgataaag aaagaaaccg gacgaacacc
    15781 tataaaaact taagcaaaaa ggttaccttc gcggaaacaa gatttcgctt tggaagtaca
    15841 agaattattg aaactatatg ccgctcaccc gcaagtgacg gcgctggaca ccttactgaa
    15901 aaacgatacg tcccgcaata tattcctaaa gggactgaat ggctcgggtc cagcaatgac
    15961 gatcgcctct ctttttacga aaggaagggg aagttatgtg tgcgtgttga acgaccaaga
    16021 ggaagccggc tatttctatc acgacttgat gcaacttacc gccagcaatg aggtatactt
    16081 cttcccatcc gcttaccgga gggccatcaa gtacgggcat gtcgatccgg cgaacgagat
    16141 cctgcgcacc gaggt
//
LOCUS       DBMDTB010000091        15939 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_1169_length_15939_cov_10.646357, whole genome shotgun
            sequence.
ACCESSION   DBMDTB010000091 DBMDTB010000000
VERSION     DBMDTB010000091.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 15939)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 15939)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15939
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1169_length_15939_cov_10.646357"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            127..693
                     /locus_tag="ACZPB4_13205"
     CDS             127..693
                     /locus_tag="ACZPB4_13205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YIP1 family protein"
                     /protein_id="HIR1099207.1"
                     /translation="MYKEIFRWVIAIISQPAKAWALLAKKGEKQEEFLSRFVYPLIGF
                     VTVAAFLGVLFTRKEFDLELALKSSIRTLVSSFGGFYLGAYLMNEIWQGIFKREKDLK
                     LWLRFVGYSSSLMFALNIVLMLLPEFFFLRIFILYTFYIVWEGAGPYMGVEEKIRLKF
                     VGFTTAIILLTPAVIEILLSMLMPGLSF"
     gene            708..1169
                     /gene="smpB"
                     /locus_tag="ACZPB4_13210"
     CDS             708..1169
                     /gene="smpB"
                     /locus_tag="ACZPB4_13210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007657455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HIR1099208.1"
                     /translation="MKEKISNNIQIKNKRATFDYELLDTFTAGIVLTGTEIKSIRLGK
                     ASLVDTFCIVEKGELWVKNMYIAEYFYGTYNNHNARRDRKLLLTKKELRKIEGAVRAS
                     GFTIVPTRLFINEKGLAKVVVAIARGKKEYDKRDSIRERDDRREMDRAFKR"
     gene            1176..2135
                     /locus_tag="ACZPB4_13215"
     CDS             1176..2135
                     /locus_tag="ACZPB4_13215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011965997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside recognition domain-containing
                     protein"
                     /protein_id="HIR1099209.1"
                     /translation="METGQGVIGRVWGCILKALPKAGKTCLWLLKIILPISLLVRILQ
                     YSGILGQISDWLVPVFSLVGLPGETAIVFITSIFSPLYAPIALITSMSLGVREATILA
                     LMCLTSHNLMVESSVQAKTGSSFWEMTLLRLIMSFVIAFSLNWVMPHEGWGQVGIAQS
                     AAVCDNWLEVFVLWFTSSMKVVISILIIVTALMILHYILEEFNLMKGLSSVFSPLMRL
                     FGLPQDAAFLWLVGNVVGLAYGGAIMVEQMEQRKLSYGDGNLLNHHLAVCHSLLEDTI
                     IFAAIGVPVLWVVPTRLFFAIAVVWILRGYSYMYARKVKHIYE"
     gene            2128..5820
                     /gene="metH"
                     /locus_tag="ACZPB4_13220"
     CDS             2128..5820
                     /gene="metH"
                     /locus_tag="ACZPB4_13220"
                     /EC_number="2.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008771641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008705 - methionine synthase activity
                     [Evidence IEA];
                     GO_function: GO:0031419 - cobalamin binding [Evidence
                     IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HIR1099210.1"
                     /translation="MNKERFLRLLNERILILDGGMGTMIQSFKLNEQDYRGERFADFP
                     GQLKGNNDLLCITRPDVIQSIHRQYLDAGADIFATNTFNANAISMADYAMEAYVREIN
                     LAAGRLSREVADTYMAEHPDRTIFVAGSIGPTNKTASMSPDVSDPAYRAVTYKDLYNA
                     YKEQVEGLVDGGVDIILFETTFDTLNVKAGLEAAEVVLKEKEKDLPIMLSLTLSAQGG
                     RTFSGQTLLAFLASIQHTHIVSVGLNCSFGAADMKPYLQELAKYAPYYISAYPNAGLP
                     NSFGTYDETPDKMAQHVKPFVEEGLVNIIGGCCGTTPAHISRYPELVKGAKPHIPALK
                     PDCLWLSGLELLEVKPENNFVNVGERCNVAGSRKFLRLIKEGSYEEALTIARKQVEDG
                     AQVIDINMDDGMLDAVKEMKTFLNLIASEPDIARVPVMIDSSKWEVIEEGLMCVQGKS
                     IVNSISLKEGEEVFLKHAARIKQLGAAAVVMAFDEKGQADTYERKIEICERAYRLLIE
                     KIDFNPQDIIFDPNVLAIATGMEEHNGYGLAFIRAVEWIKKNLPGAKVSGGVSNLSFS
                     FRGNNHVREAMHSVFLYHAIGKGMDMGIVNPSTSVLYEDIEPEFRTLLEDVILARRPE
                     AAEELITYAQNLHVQASGETPEKHEAWRELSLKERLEHALIKGIGDYLEDDLQEALRT
                     YSHAVDIIDGPLMSGMNKVGELFGAGKMFLPQVVKTARTMKKAVAILQPAIESEKKAS
                     GSAKAGKVIFATVKGDVHDIGKNIVSIVLSCNNYEVIDLGVMVPADVIIKKAIEEKPD
                     LVCLSGLITPSLEEMAHVADEMQKAGLTIPMMVGGATTSKLHTAVKIAPHYDYPVIHV
                     LDASQNPLIAAKLLNPDTRDAYIRELEQEQEALRASLGQKKETLASLSEARKHPIEID
                     WTGYTPVVPARMGVHVIPYIPLEEVIPYIHWTFFFSAWKLNGRFSEISQIHGCDSCRA
                     SWLAGFPEKDRAKATEAMQLYKDAVRLLDRLVNMKVEYCKAIYGFFSANSEGDTIRMG
                     DIALPLLRQQVKKEENIYKCLSDYVIPVSEERTDYVGAFVVTAGAGADCLKDKFEEEG
                     DTYNSMLLQTLTDRLAEATAEYLHEKVRKEYWGYAKDESLSIPDLYKVKYQGIRPAIG
                     YPSLPDQLLNFTLDGLLDMSRIGVSLTENGAMYPTASVSGIYIAHPSSQYFMIGSIDE
                     EQMRDYASRRNLTEEQARKLLSKNIG"
     gene            complement(5939..7495)
                     /locus_tag="ACZPB4_13225"
     CDS             complement(5939..7495)
                     /locus_tag="ACZPB4_13225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M81 family metallopeptidase"
                     /protein_id="HIR1099211.1"
                     /translation="MNRNLVLLGICLLAVSFVGEAFGQKKKPRIGIAGIQIENSVFVP
                     NRQPLVGHPVRMPDYLSPDSAMGQAATWLPTQIGYGGGRGPVTKESYDAFVEKTLEMI
                     KANMPYDAFWFYNHGACSVEGVADPEGEFMEKVRSLIGNDVLTTTTMDLHGNTSWLVA
                     LNSDLITTYRQAPHADSRESHRRGVVNLLERLESGKGRPAYKAWVAVPVLVSGEWSST
                     RVEPAKSLYALVPEVEAMPGVIDAGIWIGYVWGDNPRNQGTVMVYGDDEEQVKAGAKK
                     LAQKFWDVRKQFSLEAPGYSLEKCIDLAVASKKKPFFISDMGDNPGGGGSGEVTWTLA
                     RLLKRPEFQTDKGKSVLYCSIPGEEVVKQARKVGVGGHVEGMVGAMVDNSYEGPVKLS
                     GTVVYVSPEEDKNAESWRRKRDIAIVKTGSVYVVVGTSSPTPNLEGSGIDPKEMDIVM
                     VKQGYLVTQWYNIQADWVMAFTRGGVDQDFKKLPYKNIVRPMFPIDPDMADPELNVIM
                     VPSAKHYYGR"
     gene            complement(7530..9041)
                     /locus_tag="ACZPB4_13230"
     CDS             complement(7530..9041)
                     /locus_tag="ACZPB4_13230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RagB/SusD family nutrient uptake outer membrane
                     protein"
                     /protein_id="HIR1099212.1"
                     /translation="MFKNKYIIGIVLAILTGFSSCADLDLAPLGSPEAGEISEERQAF
                     LRLTAVYSVMKDFRYTWSMQCFGDVLSNDATYSGSSNDAQTFTLLENYQYQADHTEIL
                     NKYRYSYQCINKANLFIRDMEMADDALFSKYNREQMIGEAKFIRAYTYFELVKTFGGV
                     PCYTGVLDLDHERLGRASVEEIYSVIEQDLNDAVSVLPKKSEVANYESSYAGRITKGA
                     AIAMQTRIYLYEKKYDEVKKAFEKFQNECGGEYSLVAPEDYAWQFSLDGEHCSSSILE
                     VNMYVSSTQSSYNVNNGNRHVLMSMPRNMTIGFGCAQPTQALADAYDAEGDVIRKKTT
                     LLSTEEAIEIETAAKGDVAPVTDDRTGWYNRKLYLAPGQREENRGNNQPTNLRLIRLA
                     EVYLNYAEACYFSGDIANAQKYLNEVRSHVNLAPKNHTGSQLFEDIMNERHLEFGMEG
                     FRFFDVVRVGWGEKVFNGTKKAEFGAKTPFSAGAEVLPIPQTEIDISDGLITN"
     gene            complement(9055..12249)
                     /locus_tag="ACZPB4_13235"
     CDS             complement(9055..12249)
                     /locus_tag="ACZPB4_13235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SusC/RagA family TonB-linked outer membrane
                     protein"
                     /protein_id="HIR1099213.1"
                     /translation="MNEICKGNPNPRLNTKTKLGRVMKLTSIPLFVFTTGVYASVHSP
                     NMRIKSDIMIIEKPSIVSTPQQNTRQITGTVIDATGMPIIGANVMVKGTTNGTITDID
                     GKFTLEVAKDAILQVSYIGYMNQEIPVGNKSVLSISLQEDTQKLDEVVVIGYGTMKKS
                     DITGAISSVSEEKIARQAVANVSTALQGLATGVSVTSSSGSPGSAATIRIRGVGTVND
                     AEPLFVVDGMPVTDINYLNTSDIQSMEVLKDASASAIYGSRGANGVILITTKKGAAGK
                     TTVTLDAYWGMNKILNNLDLMSGPEWYDYQEQLNTVRSVPINLALVNRNVSTNWMDEI
                     THTAFMHNYSVGISGGKENDYKFNLGLNYINQDGTIKKSNYERFSVRQSTEKTVLKDH
                     LVVGTNASIARSTDASISERNSSNVYDSDYGVVSNAIRLDPVTPAQNADGSYGYSPYI
                     DYYNPLASIMYRDNQREKLAFIGNMYGEWQIIKGLKFKSSFGAEIRRVDNKTFSPVYE
                     VSSSQRNLESSLSKSQTKGHYYTFENTLSYEKTFAEKHSISALVGYTNEWGKQETLSV
                     NARDLIGESDNLHYIDATLDKNKTTASNSATEYGLMSYLGRLHYDYNNKYLITATFRR
                     DGSSKFSSKNRWGNFPSFALGWRIDNEPFFQKLNAEWVSSLKLRGGWGQIGNQNITNY
                     VDRSLLSLSTQYGALFGARENETLYQGIAVSRLGNPDIKWETTESLNIGLDASFFNTR
                     MVFSFEYYYKTTKDMLLAAPMPIYMGYASNTYTNIGEANNRGIEMNLEWRDKTESGFE
                     YNVGVNMSTIRNRMTKLNGGTPISDGPFRNGSMYLTYTNEGMPIGAFWGYKTDGLIQT
                     QEQLNAVKRADFQPNAELGDVLFVDTNGDGKLDSSDRCMIGNPIPDIIYGINMGMAWK
                     GFDLNLQFGGTIGNQIFNAMRYYTYFPNDITNKDRALMNYWTPNNTNTDIPRLTATDV
                     NDNDRFSDMYVENGTYFRLRNAQLGYTLPASLTQRIKLQKVRFYVSGQNLFTISSYSG
                     MDPEVGQSSSLSRGIDYGIYPQNISFTGGINVTF"
     gene            13154..14086
                     /locus_tag="ACZPB4_13240"
     CDS             13154..14086
                     /locus_tag="ACZPB4_13240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009009 - site-specific recombinase
                     activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HIR1099214.1"
                     /translation="MDEKGFVEGVRRYMSQLREEKRYSSAKSYQDALNSFIKYSGTEN
                     ISYSDINKANLHRYEAYLLEKGCMCNTVSTYMRRIRCVYNKAIEDGDAEYIPGLFQGV
                     FTGVESKRKKSLSLENQHKLMTVKVESEVLRETQLVVCLLFQYAGMSFVDFAHLKERN
                     IKNGILDYNRQKTGTPMRLEILDTAELMRKELMGDKKPASGYLFPFLSGTKTGYEAYL
                     EYNAALSRFNRNLKALKKAAGIASDVTSYTIRHSFAMALKEQNVPIEMISELLGHKSI
                     KTTQIYLRSFSLEKMTEVNSTCFGCVYNYVSKVG"
     gene            14507..15169
                     /locus_tag="ACZPB4_13245"
     CDS             14507..15169
                     /locus_tag="ACZPB4_13245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006354 - DNA-templated transcription
                     elongation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0140673 - transcription elongation-coupled
                     chromatin remodeling [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination NusG
                     family protein"
                     /protein_id="HIR1099215.1"
                     /translation="MRANVVKTVVNSVPHEGIDAVGVERTIPENPLRRKSDQKHWYIA
                     IVNNKSEKLCRDKLEKRIASQPEGEKDYEVYIASQKEMCLLPSGKRKQVDRIVFRSIV
                     FIRCTDVLRRKEIVHLPYIKRFMVNIAGERSGGIRPVAFIPDEQMVKLRRMLDDSEEP
                     VIIDPRPLPLGARVRINGGKLHGLEGNVLEVEDGNLNFVIRVDLLGCAKVNITRDLLE
                     LL"
     gene            15179..15616
                     /locus_tag="ACZPB4_13250"
     CDS             15179..15616
                     /locus_tag="ACZPB4_13250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008771646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099216.1"
                     /translation="MDTHYGKKEDRSGVRLISLLGNHLKEILKRESDNRAFIHLYCTG
                     PYWVAFEKSAYLLRQISSRTLVTPLSLTTYPFPIVMVSWTDGELRSYTRNHLFHREGN
                     DYGRLSVPTRTLDGYKEWHKEEVRYFPMQEVKNTSMDRDMEID"
BASE COUNT         4128 a         3442 c         3797 g         4572 t
ORIGIN      
        1 tttaaaataa attatgccga acgctataat gcggatacaa ccgcatgtgt ttggggggct
       61 accgacgtat ttacgttgcg ttttacgaat taaatatata cttttgctat ttaaaagtaa
      121 acagagatgt ataaggagat atttaggtgg gtaatcgcta tcatctcaca gccggcgaag
      181 gcgtgggcct tgttagcgaa aaaaggagag aagcaggagg agttcttatc ccgattcgtg
      241 tatcctttga tcggcttcgt taccgtcgca gcttttctgg gcgtattgtt tacgcggaag
      301 gagtttgatt tagagctggc cttgaagtcg tctatccgga cattggtgtc ctcgttcggt
      361 ggtttttacc tcggggctta tctgatgaac gagatatggc aaggtatatt taaacgggag
      421 aaggatttga aactgtggtt gcgcttcgtc gggtattcct catcgttgat gttcgctttg
      481 aatatcgtat tgatgttgct tcccgagttt ttcttcttgc ggatatttat cctttataca
      541 ttctatattg tttgggaagg cgctggtccg tatatgggag tcgaggagaa gatccgtctg
      601 aagttcgtag gatttacaac cgccattata ttactgactc cggcagttat cgagattttg
      661 ttatcgatgc tgatgcccgg tttgagtttt tgacagaata acacaagatg aaagagaaga
      721 ttagtaataa catacagata aagaataagc gggcgacgtt cgattacgag ttgctcgaca
      781 cttttacggc cgggatcgta ctgaccggaa cggagattaa atcgatccgt ttagggaagg
      841 cgagtttggt agatacgttt tgtatcgtgg aaaaagggga actgtgggtg aagaatatgt
      901 acatcgccga atatttttac ggtacgtaca ataatcacaa cgcacggcgg gaccggaaat
      961 tacttcttac caaaaaggaa ttacgaaaga tcgagggtgc ggttcgtgct agtggtttta
     1021 cgatcgttcc cactcgtttg tttatcaatg agaaaggatt ggcgaaagta gtcgttgcga
     1081 tcgcacgagg taaaaaggaa tatgataagc gagactccat ccgggaacgt gacgaccgac
     1141 gggagatgga tcgggctttc aaacgataag tcgagatgga aacagggcaa ggcgtgatcg
     1201 gtagggtttg gggatgtatc ctgaaagctc tgcctaaagc aggcaagacg tgtttatggc
     1261 tgctaaagat tattttgcct atttctttat tggtccgtat attgcaatat tccggaatat
     1321 taggtcagat ctcggattgg ttagtgcccg tgttctcgtt ggtgggtctg ccgggggaga
     1381 cagccattgt ttttataacc agtatattct ccccattata tgctccgatc gctttgatca
     1441 cctcgatgtc tttaggagtc cgtgaagcta cgatattggc attgatgtgc cttacttccc
     1501 ataatctaat ggtagaatcc tccgtacagg caaagaccgg gtcttctttc tgggagatga
     1561 cgctgctccg tttgatcatg agtttcgtga tcgccttttc tttgaattgg gtaatgcccc
     1621 atgaaggatg gggacaggtc gggatcgctc aaagcgcggc tgtatgcgat aattggttgg
     1681 aagtattcgt actttggttt accagctcga tgaaggtggt gatttctatt ttgataattg
     1741 ttacggcttt aatgatcctt cattatatat tggaagagtt taatctaatg aaaggattgt
     1801 cctcggtctt ttctccgctg atgcgattat ttggcttgcc tcaagatgcc gcttttttgt
     1861 ggttggtagg taatgtggtc ggactggctt atggcggggc tattatggta gagcaaatgg
     1921 agcagaggaa gttgtcttac ggtgacggca acttgctgaa ccatcatttg gccgtgtgcc
     1981 attccctgtt ggaagatacg atcatctttg ccgcgatagg ggtacccgtt ctttgggtgg
     2041 tgcctacccg tctgtttttc gccatcgctg tggtatggat cctccgggga tatagttata
     2101 tgtacgcaag aaaggtaaaa catatttatg aataaggaac gatttctgcg actcttgaat
     2161 gagcgcattt tgatcttgga tggtggtatg ggtaccatga tccaaagttt caaactaaac
     2221 gaacaagatt accgaggcga acgtttcgcc gattttccgg gacaattgaa ggggaacaat
     2281 gatttattgt gtatcacccg cccggatgta atccagtcta ttcatcgtca gtatttggat
     2341 gcgggagcgg atatcttcgc tacgaatacg tttaacgcga atgctatttc catggcagat
     2401 tatgcgatgg aggcctatgt acgtgagata aatctggccg ccggccgatt gtcgagggaa
     2461 gtggcggata cctatatggc agagcatccg gatcgtacga tcttcgtggc cggatcgatc
     2521 ggtcctacta ataagacagc ttccatgagt ccggatgtaa gcgatcccgc ttatcgtgcc
     2581 gtcacttata aagatttgta taatgcctac aaggagcaag tcgagggact tgttgacggc
     2641 ggggtggata tcatcctttt cgagactact ttcgatacgt tgaacgtaaa agcgggattg
     2701 gaagcagctg aggtcgtgtt gaaagagaaa gaaaaagacc tgccgattat gttgtctttg
     2761 actttgtccg cgcaaggtgg acgaacattt tccggacaga ctttattggc cttcttagct
     2821 tccatacagc atacacatat tgtttcggtt ggcttaaact gctctttcgg agcagcggat
     2881 atgaagccct atttacaaga gttggcgaag tatgccccct attatatcag cgcttatccg
     2941 aacgccggat tgccgaatag ttttggtacc tatgacgaga cgccggataa aatggcccaa
     3001 catgtgaagc cttttgtgga agagggatta gtgaacatta tcggaggctg ttgcggaacg
     3061 actccagcgc atatctcccg gtatccggag ttggtgaaag gagctaaacc gcatatcccg
     3121 gctttgaaac cggattgcct gtggctgtcg ggcttggaac tgttggaggt gaaaccggag
     3181 aataatttcg tgaacgtggg agagcgttgt aatgtggccg gttctcggaa attcttacgc
     3241 ttgataaaag aaggcagtta tgaggaagcg ttgacgatcg ctcgtaagca agtggaggat
     3301 ggcgcccaag tgatcgatat caatatggac gatggtatgt tggatgccgt gaaagaaatg
     3361 aagacattct taaacttgat cgcctccgaa ccggatattg cccgtgtacc cgtcatgatc
     3421 gattcttcta aatgggaagt gatcgaggaa ggcttgatgt gcgtgcaagg aaagagcatc
     3481 gtgaattcca tctccttgaa agaaggagag gaggtcttcc ttaaacatgc cgcccgtatt
     3541 aagcaactgg gtgcggctgc ggtcgtgatg gctttcgacg agaaggggca ggcggatacc
     3601 tatgaaagaa agattgagat ttgtgaacgg gcctatcgcc tattgatcga gaagatcgat
     3661 ttcaatcccc aagatattat ttttgacccg aacgtattgg cgatcgctac cggtatggag
     3721 gaacataatg gctatggtct ggcgtttatc cgtgccgttg aatggatcaa gaagaacttg
     3781 ccgggtgcga aggtgagtgg tggtgtaagt aatttatctt tctctttccg ggggaacaat
     3841 catgtacgcg aggctatgca ttccgtattt ctatatcatg cgatcgggaa ggggatggat
     3901 atgggtatcg tgaatccgtc tacctccgta ctttatgagg atatagagcc ggagttccgt
     3961 accttgttgg aagacgtgat cttggcacgc cgtccggaag ctgccgagga attaattact
     4021 tatgctcaaa atttacatgt tcaagcttcc ggagaaactc cggagaagca tgaggcttgg
     4081 cgtgagcttt cattgaagga gcgtttggag catgccttaa tcaaagggat cggagactat
     4141 ttggaggatg atttacaaga agccttgcgg acttattcgc atgccgtgga tataattgac
     4201 ggtccgttaa tgagcggaat gaataaggtc ggcgagttat tcggtgccgg aaagatgttt
     4261 ctccctcaag tcgtgaagac cgcacgtacg atgaaaaagg ccgtagctat tttacaaccg
     4321 gccattgaat ctgaaaagaa agcttccggc tctgcgaagg ccggtaaagt gattttcgct
     4381 acggtaaaag gggatgtaca tgatatcggt aagaatatcg tctctatcgt attgtcttgt
     4441 aataactacg aggtgattga tttaggggta atggttcccg cagatgtgat cataaagaaa
     4501 gcgatcgagg agaaaccgga tctggtttgc ttatccggcc tgataacccc ttctttagaa
     4561 gagatggcgc atgttgcgga cgagatgcag aaagcgggac ttacgattcc tatgatggtg
     4621 ggtggcgcta cgacctccaa attgcatacg gcggtgaaga tcgctccgca ttatgattat
     4681 ccggtgattc atgtgctgga tgcctcacag aatccgttga tcgccgccaa actattgaat
     4741 ccagataccc gtgacgctta tatcagggag ttggaacaag aacaagaagc cttgcgtgcc
     4801 tctttagggc agaagaaaga gaccttggct tctctttcag aggctcgtaa gcatccgata
     4861 gaaatagatt ggaccgggta tacaccggtt gttccggccc ggatgggggt acatgttatc
     4921 ccttatatcc ccttggaaga agtgattcct tatatccact ggaccttctt ttttagcgca
     4981 tggaaattga atggccgttt ctcggaaatc tcccagatac atggttgcga ttcttgtcgt
     5041 gcctcttggt tggccggatt cccggaaaaa gatcgtgcga aggctaccga ggcgatgcaa
     5101 ttatacaagg atgctgttag gttattggat cggctggtca atatgaaggt tgaatattgt
     5161 aaagcgattt acggattttt ctcagcgaat agtgaagggg atacgatccg aatgggtgat
     5221 atagcactgc ctttattacg tcagcaagta aaaaaagagg aaaatattta taaatgtctt
     5281 tccgattatg taataccggt ttccgaggag cgaactgatt atgtaggggc gtttgtcgtt
     5341 accgctggag ctggcgctga ttgtttgaag gataaatttg aggaagaagg cgatacctat
     5401 aattcaatgt tgctgcaaac cttgaccgat cgcctagcgg aagctacagc cgaatatctc
     5461 catgagaaag tacgtaaaga atattgggga tatgctaaag acgaatcctt gtctatcccg
     5521 gatctttaca aggtgaaata ccaaggaatc cgtccggcta tcggttaccc ttctcttccg
     5581 gatcaattat tgaatttcac attggatgga ttgctcgata tgtcgcgaat tggtgtttcg
     5641 ttaaccgaga atggtgccat gtatcctacg gcttcggtta gtgggattta tattgcccat
     5701 ccctcttctc aatatttcat gatcggttct atcgatgagg agcagatgag agattatgcg
     5761 agccgccgga atttaacgga ggaacaagcc cgaaagttgt tgagtaagaa tataggataa
     5821 tttattaaca tcactgcaac tcgggttgca gtgatgctgc aatgcctgtg cagtaatact
     5881 gcaacaccta ttgcagtaac actgcatagg tattgcagta aaaaacaatc aatacgatct
     5941 atctgccata gtaatgcttg gcggaaggaa ccatgataac gttcaattcc ggatcagcca
     6001 tatctggatc gatcgggaac atcggtctca cgatattctt atagggaagt ttcttgaagt
     6061 cctgatccac gcctcccctt gtaaaagcca tcacccaatc cgcttgtata ttgtaccatt
     6121 gggttacaag gtaaccttgt ttaaccatta cgatatccat ttccttcgga tcgatacctg
     6181 aaccctctag gtttggagtg ggagacgatg tgcctactac cacataaacg cttccggtct
     6241 ttacgatagc gatatccctt ttccgtctcc atgattccgc gttcttgtct tcttccgggc
     6301 tgacataaac cacggtaccc gacaatttca cgggaccttc gtaggaatta tcgaccatgg
     6361 cacctaccat gccttctacg tgtccgccta cgccgacctt acgtgcctgc ttaaccactt
     6421 cttctcccgg gatggagcaa taaagaacgc tctttccctt atcggtctgg aattccgggc
     6481 gtttcaagag cctcgccaaa gtccaagtga cctcacctga accacctcca ccgggattat
     6541 ctcccatatc actgataaag aaaggcttct ttttacttgc tactgccaaa tcgatacatt
     6601 tctcgagcga atatcccgga gcttccagcg agaactgctt acggacatcc cagaatttct
     6661 gggcgagttt cttcgccccg gctttaacct gttcctcatc gtcaccgtaa accatcacgg
     6721 ttccttggtt ccgtgggttg tctccccaaa cataaccgat ccagatccct gcgtctatca
     6781 ctccgggcat ggcttcaacc tcgggaacca atgcgtacag cgatttcgca ggctcgacac
     6841 gggtactcga ccattcgccg gatactagga caggaacagc aacccatgcc ttgtatgccg
     6901 gacgtccttt ccccgactca agacgttcca acaaattgac gacccctcgc cgatgcgatt
     6961 cgcgagaatc cgcatgcggt gcttgacgat aagtcgtaat caaatcggag ttgagagcta
     7021 ccaaccaaga cgtatttccg tgaaggtcca tcgtggtggt agtcaagaca tcgtttccga
     7081 tcaagctacg caccttctcc atgaattcgc cctcgggatc ggctacgcct tccacgctac
     7141 aagctccgtg gttataaaac cagaaggcgt catatggcat attggccttg atcatctcca
     7201 atgttttttc cacaaacgca tcgtacgatt cttttgttac ggggcctctt ccaccgccat
     7261 agccaatctg cgtgggaagc caagtggccg cctgtcccat tgcggagtct gggctgagat
     7321 agtctggcat tcttacgggg tgtcctacga gcggttgcct attcgggacg aacacgctgt
     7381 tttctatctg tataccggca ataccgatac gaggtttttt cttctgtcca aaggcctctc
     7441 caacgaacga tacggccaag agacagattc cgagcaatac taaattccta ttcatactat
     7501 tatgattttt gcgaattgtt atttccttat taattagtta ttaaaccatc actaatatca
     7561 atctcggttt gaggtatagg caatacttcc gcaccggcgc tgaaaggagt cttagctcca
     7621 aattccgcct tcttggttcc gttaaagact ttctcgcccc atcctacacg taccacgtca
     7681 aagaaccgga aaccttccat tccgaactcc agatgacgct cattcatgat gtcttcaaac
     7741 aattggcttc ctgtatggtt cttaggagcc aagttgacat gacttcttac ctcattcaga
     7801 tacttttgcg cattagcaat atcgccgctg aaataacaag cctcggcata gttcaaatat
     7861 acctccgcga ggcggataag cctgaggttc gtgggttgat tatttccccg attctcctct
     7921 ctttgcccgg gcgcgagata tagtttgcga ttgtaccaac cggttcggtc gtccgtaacg
     7981 ggtgccacat cgcctttggc cgcggtctcg atctctatag cctcttccgt ggaaaggaga
     8041 gtggtcttct ttcgtatgac atccccctca gcatcataag cgtccgccaa ggcctgtgta
     8101 ggttgcgcgc aaccgaagcc gatcgtcatg tttcggggca tagacatcag cacgtgacgg
     8161 ttaccgttat ttacattata cgaactttgg gtggaagaga catacatatt cacttctaga
     8221 atagaagagg agcagtgctc gccgtccagt gagaactgcc aagcgtaatc ctccggagcg
     8281 accaagctat actcaccccc gcactcattc tggaatttct cgaaagcctt ttttacctca
     8341 tcgtattttt tctcatacag ataaatacgt gtttgcatgg cgatggccgc gcctttggta
     8401 atccttcccg catagcttga ctcgtagtta gccacctcac ttttcttagg taatacgcta
     8461 accgcatcgt ttaggtcttg ctcgataacc gagtatatct cttcgacaga cgcacgtccg
     8521 agtctctcat gatcgagatc caagactccc gtatagcaag gaacaccacc aaaggttttc
     8581 acaagctcga aataagtata ggcgcgaata aacttggcct caccgatcat ctgttccctg
     8641 ttatatttcg agaatagggc atcgtctgcc atttccatat cccgtataaa caaattggcc
     8701 ttattaatac attggtaaga ataccgatat ttgttcaaga tctcggtatg atccgcttga
     8761 tactgataat tctccagcaa cgtgaaggtt tgtgcgtcgt tcgaagaacc gctgtaggtc
     8821 gcgtcattcg acaacacgtc gccgaaacat tgcattgacc atgtgtaacg gaagtccttc
     8881 atgacggaat agacagcggt cagacgcaag aaagcttgtc tttcctctga tatctctcca
     8941 gcctccggac ttcctaacgg agctaaatcc aaatctgcgc aactgctgaa tcctgttaaa
     9001 atcgctagta cgattcctat gatatatttg tttttaaaca tgacattata aattttaaaa
     9061 agtaacatta atacctccgg tgaatgaaat gttctgagga tagataccgt aatctatacc
     9121 tctagacaaa gagctggact gacccacttc cggatccata cccgagtaac tggatatcgt
     9181 aaacaagttc tggccgctta cataaaaacg tactttttgt agttttatcc tctgcgtgag
     9241 agaagcgggc agggtataac ctagctgggc gtttctcaag cggaaataag tcccgttttc
     9301 tacgtacatg tccgagaagc ggtcattgtc gtttacgtcc gtagccgtca ggcgagggat
     9361 gtccgtattt gtattatttg gcgtccaata gttcattaac gctctatcct tgttcgttat
     9421 atcgttcggg aagtaggtgt aataacgcat cgcgttaaat atctgattac cgattgttcc
     9481 accaaactgc aaattgaggt cgaagccttt ccacgccata cccatgttga taccgtatat
     9541 gatatccgga ataggattac cgatcatgca tctatcactt gagtctaact tgccatcgcc
     9601 gttcgtatct acgaacaata catcgcccaa ttcggcatta ggttggaaat ccgcccgctt
     9661 aacggcattc aactgttcct gtgtttggat aagcccgtct gtcttatagc cccagaacgc
     9721 accgataggc ataccttcat tcgtataggt gaggtacatg cttccgtttc ggaatggtcc
     9781 atcggagatt ggtgtgccac cattcaattt cgtcatgcgg ttacggatgg tcgacatatt
     9841 tactcccacg ttgtattcga aaccgctttc ggtcttgtct ctccactcga gattcatctc
     9901 gataccgcgg ttgttcgcct cgccgatatt ggtgtaggtg ttgctggcat atcccatgta
     9961 gataggcata ggagcggcca gcagcatgtc cttcgttgtc ttgtaataat actcgaagct
    10021 gaagaccatg cgggtgttaa agaagcttgc gtcaagaccg atattcagag attcagtggt
    10081 ttcccattta atatccggat tgcccaatct gctcacggca ataccttgat acaaggtctc
    10141 attctctctc gctccgaata aagcgccgta ttgcgtactc aatgacagca aactacgatc
    10201 cacataattg gtgatattct gatttccgat ctgtccccag cccccgcgga gtttcaagga
    10261 ggaaacccat tcggcgttca atttctggaa gaacggttcg ttgtcgattc tccaacctag
    10321 agcgaacgag gggaagttac cccagcgatt cttggaagag aatttagagg agccgtctcg
    10381 ccggaaagtg gccgtaataa ggtatttgtt attgtaatcg tagtgtaggc ggcccagata
    10441 agacatcaaa ccatattccg tagcgctatt gctggccgtg gtcttgttct tgtccagcgt
    10501 agcgtctata taatgcaggt tatccgactc tccgataaga tctctcgcgt ttacgctcaa
    10561 ggtttcctgc ttaccccatt cgttggtata acctacgaga gcggatatgg agtgcttctc
    10621 ggcaaacgtt ttctcatacg aaagggtatt ctcgaacgta tagtagtgcc ctttggtctg
    10681 cgacttcgat aaactactct ctaaatttct ttggcttgag gatacctcat agacaggcga
    10741 gaaggtttta ttgtctaccc ttctgatttc cgctccgaag ctactcttga acttcaatcc
    10801 ttttataatc tgccattccc catacatatt gccgatgaaa gcaagtttct cccgctgatt
    10861 atcccgatac atgatacttg ccaatgggtt atagtagtca atataaggag agtaaccata
    10921 tgaaccgtct gcgttttggg cgggagttac cggatccaaa cggattgcgt tacttacgac
    10981 accatagtcg gagtcgtaca cattactact gttgcgctca ctaatacttg cgtcggtaga
    11041 tctcgcgatc gacgcgttgg tacccactac caaatgatct ttgagcaccg ttttttccgt
    11101 gctttgacgg acactgaacc gttcgtagtt ggatttcttg atcgttccat cttggttgat
    11161 atagttcaag cccagattga atttatagtc gttctcttta ccaccgctta tgccgacact
    11221 gtagttatgc ataaaggccg tatgcgtaat ctcgtccatc caattggtgg aaacattacg
    11281 attaacaagg gccaagttga tgggaacgct cctcactgtg ttcaactgtt cctgatagtc
    11341 gtaccattct ggacctgaca tcaaatcgag attattcaat attttgttca taccccaata
    11401 cgcatcgagc gtaacggtgg tttttccagc ggcgcctttt ttcgtagtga taaggattac
    11461 gccgttcgca ccacgggaac cgtagatagc ggaagcggaa gcgtctttaa gcacctccat
    11521 agactgtata tccgatgtgt tcaggtagtt tatatccgtc acgggcatcc cgtccacgac
    11581 gaacaatggt tccgcgtcgt ttaccgtacc gacacctctg atacggatcg tggcggcgga
    11641 acccggagat ccggaactgg aagtgacgga tacaccggta gccaagcctt gcaatgcggt
    11701 agaaacattg gccactgctt ggcgagcgat tttctcctcg ctcacggacg agatagcccc
    11761 cgtgatatca cttttcttca tcgtaccgta gccaatcact accacctcat ccaacttttg
    11821 tgtgtcctct tgcaaggaga tgcttaaaac cgatttattg cctaccggaa tctcctggtt
    11881 catataaccg atataggaca cttgcaaaat agcgtctttg gctacttcca acgtgaattt
    11941 tccatctata tccgttattg tcccgtttgt tgtccctttt accatcacat tggcgccaat
    12001 tattggcata ccggtagcat caatcacggt tccggtgatc tgacgggtgt tttgttgcgg
    12061 ggtggatacg attgatggtt tctctataat catgatgtcg cttttaatgc gcatgtttgg
    12121 ggagtgtacg gaagcgtata cacctgtggt aaaaacaaat agcgggattg aggttaactt
    12181 catgactctg cccaatttag tttttgtgtt taatcggggg ttaggattcc ccttacaaat
    12241 ttcattcata catttgtaat gttttagtgt tagtattaat tgatttaaag gcgtttagaa
    12301 acttgtttgg ctggattata agccatatct tccagccagt ttccttgcta gatatggttc
    12361 atgatggctc ctgtttcata ggctctcctt tctttaagat taactttagt aaactgaata
    12421 tgtttatttg gttgtttgat ttgcaatatt cgtgaaaaaa aacgacacct gcaagcaagt
    12481 ctctgctaat ttaatattgt gtattcaatt gatagaagtc attaatacgg cttaattatg
    12541 tcaatttgtc atttctctct ccttctgctt cttgtatttg agataggata gggtgtgtgt
    12601 ttattatatg cgattctctg gtagttaagc cctgacgaat agaatgtgta tgaaggaaaa
    12661 tacttgcagt ttgccttctt tttatcaata tccgccgaat tattatatct cttgtttcag
    12721 aaaactaata aatgcttcct gaatagtatt tgaaaatcaa ttgacttttt tccgttctag
    12781 ggtgcaaagg ctctaatata gtctcgattt tcagtgtaca gaagattatg attaaaagta
    12841 gatcccaact aaattagagc aagtgccgga taattcgaac taggtgccgg gtagatgtcg
    12901 gttatctgcc gggaaataga aattataagc cgactaaata catacaagtt taggatatat
    12961 cctaaaaaat gtgctgtttt gggtactaaa ttccataata atcggtttaa aagcaattgt
    13021 tttgaaaaag tctgtgtttg aaatatattt aaaaagttaa cattatgata gtgtttcggt
    13081 aattcttttt gcattcagat agtatggtta tatttgtcta ttcatttcaa atattattaa
    13141 aaaacagaga gatatggatg agaaaggatt cgtggaaggg gtgagaaggt atatgtccca
    13201 gttacgagag gaaaagcgtt attcctccgc caaaagttat caggatgcgt tgaactcctt
    13261 tataaagtat agtggaacag agaacatttc ctattcggat atcaataagg ccaatcttca
    13321 ccgatatgag gcttatttgc tggagaaagg ctgcatgtgc aacacggttt ccacttatat
    13381 gcgtcgtatc cgttgcgtct ataacaaggc gatcgaagat ggtgatgcgg aatatatccc
    13441 tggtttgttc caaggagttt ttacgggagt ggagagtaag cgcaagaaat ccctatcctt
    13501 agagaaccaa cataagttga tgacggtgaa ggtagagagt gaggtgctaa gggagacaca
    13561 actggtcgtt tgtttgttgt ttcagtatgc aggaatgtcg ttcgtggact tcgcccacct
    13621 aaaagaaagg aatatcaaaa acgggatatt ggactataat cggcagaaga caggcacacc
    13681 gatgagactg gaaatcttgg atacggcaga attgatgcgc aaggaattaa tgggtgacaa
    13741 gaagccggcc tcaggctatt tattcccttt tttgagtgga acgaagacgg gctatgaggc
    13801 atatctcgaa tacaatgcgg ccctatctcg gttcaatcga aatttgaagg cgttgaaaaa
    13861 ggccgctgga atagcatcgg atgttacctc ttatacgatc cgccattcct ttgccatggc
    13921 attgaaagag caaaatgtcc ctatagaaat gatcagtgaa ttattggggc ataagtccat
    13981 caagaccacc cagatttatc tgagaagttt ctctttagaa aaaatgacag aggtgaatag
    14041 cacttgcttt ggttgtgtct ataattatgt gtcgaaagtg ggatgaggct acttagtgag
    14101 tagcgtttgt ttcacgccgc aaatgtagta aaaaataaca aaaaacaagc aatcattagg
    14161 gtttgtttgt gtttccagtt ggattctcgt taaatcttcg ttcttatttc tgatgtatag
    14221 acatggcaat agagacgaaa tggcctcgta tttccgaaat catcacgtcc cccccctaaa
    14281 atcgaacata cattcttgta gagatgggta taccccgtct catcccctct aaaagatgtt
    14341 ttaaattact gtcagacggt gggagacgga gcatgctccg tctctacaac tgagtaataa
    14401 ccattctccc accttttgcg ctactcacta agtagcctaa tttctcacat ggcgaaaaag
    14461 ggttatggtg catatatcaa actatctctt ttaagcaatc aacgaaatgc gagcgaatgt
    14521 tgtaaaaacg gttgtaaatt cggtacctca tgagggtatc gacgccgtag gcgttgaaag
    14581 aaccattcct gaaaacccgt tacggcgaaa atctgatcag aaacattggt acatcgctat
    14641 cgtcaacaac aagtccgaga aactatgccg tgacaagctg gaaaagcgca tagccagtca
    14701 gccggaaggc gagaaggact atgaggttta tatagcctcc caaaaagaga tgtgtcttct
    14761 gccaagcggc aagcgtaagc aagtagaccg gatcgtcttc cgttccattg tattcatccg
    14821 ttgcaccgat gtcttgcgta ggaaggagat cgtgcatctt ccttatatca aacgtttcat
    14881 ggtaaacata gctggcgaac ggtctggagg catacgcccc gtagccttca ttccggatga
    14941 gcagatggtg aaactccgta gaatgctgga cgattccgaa gagcctgtca ttatcgatcc
    15001 ccgtccgctg cctcttggag cgagggtacg tattaacggc ggtaagttgc atggtctaga
    15061 aggtaacgtg ctggaagtgg aggatggcaa tcttaacttt gtgatccgtg tagatctact
    15121 gggatgtgcc aaagtaaata tcacccgtga cctgctagag ctattatgat acacatagat
    15181 ggatacgcac tatggtaaaa aagaggatag atccggagta cgccttatct cgttgttagg
    15241 aaaccatttg aaagagattc ttaagcgaga gtcggataat cgtgccttca tccatcttta
    15301 ctgtacgggt ccgtattggg tggcgttcga gaaatcagct tacctgttac gccaaatatc
    15361 ttcccgtacc ttagtgaccc cgttaagcct caccacgtac ccgtttccaa tcgtgatggt
    15421 ctcttggaca gatggcgagt tacgttccta tacacgtaac catcttttcc atcgcgaagg
    15481 caatgactac ggtcggttat ccgtccctac tcgtacgctt gacggttaca aggagtggca
    15541 taaggaagag gtgaggtatt ttccgatgca ggaagtaaaa aacacgtcca tggatcgtga
    15601 catggagatt gattaaagat acttctgagg ttcaagagag cctccaatca agaatatatt
    15661 atcgctaggt cgcaattaga aaatgagaat taggcggccg atatcgatca agaggtcagc
    15721 tatctctagt agcgaggaga gtcccttttt ctttaaccga tagactagac tcttgcttta
    15781 gcttatacca ctccaaccac ttgagaggtt cggtcgctta ttattatagt tagatagaca
    15841 ctagtgtccc gttaaaatcg ggacgagtta ttaattaatc aaataatccc ggaataaggg
    15901 gattaaattg ttctttgaca tcattgaaat tagtcttat
//
LOCUS       DBMDTB010000092        15808 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_1181_length_15808_cov_12.767110, whole genome shotgun
            sequence.
ACCESSION   DBMDTB010000092 DBMDTB010000000
VERSION     DBMDTB010000092.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 15808)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 15808)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15808
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1181_length_15808_cov_12.767110"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     regulatory      6..102
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            165..935
                     /locus_tag="ACZPB4_13255"
     CDS             165..935
                     /locus_tag="ACZPB4_13255"
                     /EC_number="2.4.2.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfide-dependent adenosine diphosphate thiazole
                     synthase"
                     /protein_id="HIR1099217.1"
                     /translation="MEQIVSSGIIDSYFEKLKSNLSVDVAIVGGGPSGIVAAYFLAKA
                     GKKVALFDRKLAPGGGMWGGAMMFNDIVVQEEAMPIIKELGVSYKEGANGTYIMDSVH
                     TTSALIYQATKAGATIFNCYSVEDVVFHNDAVAGVVVNWAPVIREGMHVDPLTIMAKA
                     VLEGTGHDCEIARVVARKNDIQLNTPTGGVIGERSLNVELGEQTTVENTKEIYPGLFV
                     SGMAANGVSGSFRMGPIFGGMLMSGKKAAELICEKLGN"
     gene            complement(992..1411)
                     /locus_tag="ACZPB4_13260"
     CDS             complement(992..1411)
                     /locus_tag="ACZPB4_13260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099218.1"
                     /translation="MKFGVNKKILLYTAGCVWIFAGINILRIGIVTWLNDTHYWLFKI
                     GEATIVFLLFFNLVFKRLFYKHSERISRKNGKHCPFSFFDVKGWIIMIFMIAFGITIR
                     TFHLLPNSFISVFYTGLSTALIITGFLFLRQGKTVRN"
     gene            1482..1886
                     /locus_tag="ACZPB4_13265"
     CDS             1482..1886
                     /locus_tag="ACZPB4_13265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6769 family protein"
                     /protein_id="HIR1099219.1"
                     /translation="MREKMKQRIVQYVVLMAGILVLLSVVIPHHHHRDGMPCYQSLTA
                     EQAHGDKSTDTHDCGCDGHNLAYFSTHISHFMDGDVDIHLMPLLVLFDYIYPPEPAFC
                     GQLLDHENAPYIESLHDTWIVSASGLRAPPMS"
     gene            1965..3167
                     /locus_tag="ACZPB4_13270"
     CDS             1965..3167
                     /locus_tag="ACZPB4_13270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005638795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HIR1099220.1"
                     /translation="MKKIYLVGAMCAYLFAGCAGNASQAGHDEHNHELEAHDHDHEGH
                     EHEGHDHEHEAGGTHPGEIVFKKALAEAVGLQTVTVNPAPFTDVIKTSGRVMAAQGEE
                     SVIVATVPGVISFGSLPFVDGTAVRKGQAVLSIASNALSDGDVAAKAKFAYETAKKEY
                     ERMQALVGDKIVSAKDFEQARLNYENAKVAYEAIAGKQTAKGVSVVSPLNGYLKNIQV
                     KEGDYVSVGQPLATISQNNRLVLRADVSERYYNDLPMIQTANFMTPYDNALYKLSDLR
                     GRLLSYGKASDMNSFYVPVTFEFDNKGAVIPGSFVEIFLLTKPMENVLSVPVSALIEE
                     QGVYSVFIRLDEEGYKKQWVTLGANNGSEVQILSGLKPGDEVVTRGAYQIKLSSASNA
                     IPAHSHSH"
     gene            3183..6266
                     /locus_tag="ACZPB4_13275"
     CDS             3183..6266
                     /locus_tag="ACZPB4_13275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HIR1099221.1"
                     /translation="MLNKIIYYSLHNRLVILVCALLLMIWGTYTAFNTDVDVFPDLNA
                     PTVVIMTEANGMAPEEVERLVTFPVETAVNGAMDVRRVRSSSTTGFSVVWVEFDWGTD
                     IYRARQIVSEKLAVLGESLPENVGKPTLGPQSSILGEMMILGLTADSTSLLDLRTIAD
                     WTIRPRLLSTGGVAQVAVIGGDIKEYQILLDPARMKHYGVGLNEVLDVCRNMNRNANG
                     GVLYEFDNEYIIRGVLSTSKAEEIAQGVVKTVNEYPVTLGDIATVKIGGKSPKLGTAS
                     ERTKPAVLITVTKQPDTSTEKLTEKLDEIVVDLRKNLPVDVHVSTDIFRQSHFIDNSI
                     NNVKKSLFEGSFFVVIVLFLFLMNIRTTVISLVALPLSLLVSIIVLHYMGLTINTMSL
                     GGMAIAIGSLVDDAIVDVENVYKRIRENRLLPPDQQRSTLEVVYDASREVRMPILNST
                     LIIVVSFVPLFFLSGMEGRMLVPLGIAFIVALFASTVVALTLTPVLCSYLLNRKATGM
                     KELREAWIARKLKVVYKRALELALAYQKWVLGTTIALFVVALVIFFHLGRSFLPPFNE
                     GSFTINVSSLPGISLDESDQIGRRAEALLLQVPEIKTVARKTGRAELDEHALGVNVSE
                     IEAPFELQDRSRDEVMNDVRKKLSTISGANIEIGQPISHRIDAMLSGTEANIAIKLFG
                     TDLNLMFTVGNQIKAAIQTIPGLVDLKVEQQIERPQLTITPKRELLAKYGIPLPEFEE
                     YINVMLGGEAVSQVYDDGKSFDLTVKTSDASRATMDDISNLMIDAAGQKVPLSYVADI
                     RSVTGPNTINRENVQRKIVISANVSERDLRSVVNEIQDRVEANIRLPEGYHIEYGGQF
                     ESEAAASRTLLLTSLMSLLVIFMLLYNEFKDVKESGVILLNLPLALIGGVIILWLTSG
                     EISIPAIIGFISLFGIATRNGMLLISHYTHLRGEGMGLRESVIQGSLDRLNPILMTAL
                     SSALALIPLALNGDLPGNEIQSPMATVILGGLLTSTFLNGFIIPIVYLIMNKNKE"
     gene            6272..7456
                     /locus_tag="ACZPB4_13280"
     CDS             6272..7456
                     /locus_tag="ACZPB4_13280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HIR1099222.1"
                     /translation="MKSYIIVAALSVLTGGLSAQTSIEDVLRSVEANNKDLQANSQLV
                     RSQKLEAKLDNNLPDPSVSYSHFWGNKEGMGFTGEFVASQSFDFPSVYVRKHKLTKAK
                     SAGLDRQGMAFRQQILLQVKEVCLDLVLLNQQKNLLDTRLRNAEQLSAFYATRLEKGN
                     ANILETNKIDLELLNARTEARMNETSRIAKLQELATLNGGIAIEFTDTVYALPDREVL
                     SFDELRTEAMQSDPQLQTLRSDQTTALRQVSVNKAKGLPGFELGYRMNPASGGERFNG
                     FLVGITIPLFSNRNNVKQAKAQARYTEMQLESASFTVENGLRQLYDQSVSLKKSIDEY
                     KDVLKRQNSLVLLNKAIQAGQISMIEYFVDVTTYYQSVQNYLQLQNQYQKVMAQLYKY
                     RL"
     gene            complement(7523..8470)
                     /locus_tag="ACZPB4_13285"
     CDS             complement(7523..8470)
                     /locus_tag="ACZPB4_13285"
                     /EC_number="1.13.12.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004497 - monooxygenase activity [Evidence
                     IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016703 - oxidoreductase activity, acting
                     on single donors with incorporation of molecular oxygen,
                     incorporation of one atom of oxygen (internal
                     monooxygenases or internal mixed function oxidases)
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent flavin oxidoreductase"
                     /protein_id="HIR1099223.1"
                     /translation="MNRICSLFGIQYPIIQAGMVWCSGWRLASAVSNAGGLGLIGAGS
                     MHPEVLREHIRKCEAATDKPFGVNVPLMYPEIDTLMRILVEEKVKIVFTSAGNPKTWT
                     KYLKDHDMTVVHVVSSSKFATKCEEAGVDAIVAEGFEAGGHNGREETTTMCLIPAVRK
                     ATSLPLLAAGGIGNGQAMLAALALGADGVQIGTRFALTKESSAHENFKKLCLNLKEGD
                     TKLLLKKLSPTRLVKGDFATAVEEAEARGASVEELRELLGKGRAKKGIFEGDLKEGEL
                     EIGQVASLFWEELSVEEVMKELIRDFKLSLENVKTQLCS"
     gene            8579..8758
                     /locus_tag="ACZPB4_13290"
     CDS             8579..8758
                     /locus_tag="ACZPB4_13290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099224.1"
                     /translation="MPENIMKTLWDESDDLHDETMSTNSVLSDDYTSNDIQDLQETIE
                     NENIEDGIESDSIEH"
     gene            8923..11043
                     /locus_tag="ACZPB4_13295"
     CDS             8923..11043
                     /locus_tag="ACZPB4_13295"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family metallopeptidase"
                     /protein_id="HIR1099225.1"
                     /translation="MNKTLMAAGLAVILGACSSSKKSDVAEGATPNPFFAEYTTPFGV
                     PPFDQIEVAHYKPALLKGMEEQSKEIEAIVANPDAPTFENTIVALDQSGELLTKVMYA
                     FGGQSSVNTTDEIQELERELYPLLSKHSDDISLNPKLFARVKSVYENQASFHLDKEQK
                     KLLEETYKSFVRGGANLPEDKQAKLRELNEKISMLQLTFGQNTLKETNDFQLVIDNKE
                     DLSGLPEDVIVKAAQTAQENGLDGKWVFTLHNPSVMPFLQYADKRDLREKIFKAYTNR
                     GNNNNENDNKEVVKQLVAARLEKARLMGYEDYAAFVLEENMAKNEKNVYDLLDKIWPS
                     ALAKAKEELADINAEIKKEGGNYEAEGWDWRYYFEKAKKAKYNLDENEMRPYFELGHV
                     REGIFYVANKLYGITFTEIKDIPKPDPDALAFECKDKDGTHLGVLYMDFFTRPGKGGG
                     AWCGGYRSQTYKDGKRVAPVVTTVFNFSKPAEGQPALLTADETETVFHEFGHALHGLF
                     CDVHYYGVSDVPRDFVELPSQVDEHWAVEPEVLKVYAKHYQTGEVIPQALVDKMIKSG
                     KYGQGFATTEYLAASYLDMDYHVLKEIPADLDIEKFEAKVLGDRGLIRQIPSRYRSTY
                     FGHTMEGGYTAGYYSYIWAEVLDCDAFQAYKETGNIFNPEVASKFRKYVLTPGGIDDA
                     MDMYVNFRGKQPSIDPLLENRGLK"
     gene            11085..13244
                     /locus_tag="ACZPB4_13300"
     CDS             11085..13244
                     /locus_tag="ACZPB4_13300"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family metallopeptidase"
                     /protein_id="HIR1099226.1"
                     /translation="MKQLIMAAGLAVMLTACGTSEKKTVEGENPFFAEYTTPFGVPPF
                     DQIKFEHYKPALLQGMEEGRKEIEAIVNNPEEPTFENTIVALDEQGALLRKVQIVFGG
                     QNSVNTNDEMQALSREMSPLLSKYSDDINLNPKLFARVKAVYDKKDELGLDKEQMKLL
                     EETYKDFVRGGANLSAEDQAKLRELNSKISMLQLTFGQNMLKETNAFKLVIDKQEDLS
                     GLPETLIANAAQAAKDAGMEGKWVFTLQNPSVMPFLQYSDKRELREKMFNAYINRGNN
                     NNENDNKEVVRDLVAARLAKAKLMGYDDYASFVLEDRMAKSSDKVYQLLDEVWKPALA
                     KAKEELADINAEIKKEGGNFEAEGWDWRYYFEKAKKAKFNLDENEVRPYLKLDNVREG
                     AFYVANKLYGITFTPIRNIPLPYPEAQAFECKDKDGSHLGVIYFDFFPRASKRGGAWC
                     GSYRPQAYKDGKRVAPVVTIVCNFSQPAPGQPALLSADEANTLFHEFGHGLHGLFRDV
                     HYSGVSGVPRDFVELPSQVMEHWVFEPEVLKVYAKHYQTGEVIPAELIEKLDKSGKYG
                     QGFATTEYLAASYLDMDFHAVSGDAADKKVIKFVDQTNNVPANLNVMDFEQQTLGRRG
                     LLKQIPSRYRTTYFNHTMGGGYTAGYYSYIWAEVLDCDAFEAFKETGDIFNQECADKF
                     RKYVLTPGGIDDAMDMYKNFRGKEPGTDPLLKNRGLK"
     gene            13362..14294
                     /locus_tag="ACZPB4_13305"
     CDS             13362..14294
                     /locus_tag="ACZPB4_13305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009009 - site-specific recombinase
                     activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HIR1099227.1"
                     /translation="MEKKDLVEGMRLYIYKLRVDGRYSTAKSYQDALNSFMRFCGLEV
                     IPYIYVNKENLRRYQAFLLNKGCTWNTVSTYMRRIRCVYNMAVEEGLAPYIPYLFKGV
                     FTGIESKRKKALPQDLLRSLMTASLDDPELRKTRQALCLMFQFCGMAFVDFAHLKKEN
                     VRGGVLEYKRQKTGTPMLIEVQSTAWESLRELSSDVGKDSPYLFPFLKGIKVGKEAYK
                     EYTSALAHFNRNLKRLARACGVSIPITSYSIRHSFAMILKEQDVPIEMISELLGHKSI
                     KTTQIYLKSFSLEKMSAVNKICFESVYNHVPKVG"
     gene            14823..>15808
                     /gene="nusG"
                     /locus_tag="ACZPB4_13310"
     CDS             14823..>15808
                     /gene="nusG"
                     /locus_tag="ACZPB4_13310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011965899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA];
                     GO_process: GO:0006354 - DNA-templated transcription
                     elongation [Evidence IEA];
                     GO_process: GO:0031564 - transcription antitermination
                     [Evidence IEA];
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HIR1099228.1"
                     /translation="MDILTGKCSDRFMAHVLKRRDQEAVRWYVLTLPTAGGGRDRISP
                     SKGLDAELSRRERRGEALFEYFSPSYVEARKVGGKMVNTKRPLLYNYVFVHASEDEIF
                     RLKRTLPLYNFLPRVSSGGRSYFPYLSDREMDTLRWVAASYSNELPVYVPDSGRLLKG
                     DRVRITSGPFTDMEAEVVVQPGGGHKDVMVRILDCMWVPLFEVRRGEYELIELNTGGK
                     HVYTHLDNDRLSEGLHDALGRYHARGVVTDEDARLAREVLRGYASLRGETDVIRCKLY
                     SLLLPAYLLLGESDEFDRLHATMRSMLPVIKAGQSRALLLVTLYGCTDSSLY"
BASE COUNT         3911 a         3360 c         4351 g         4186 t
ORIGIN      
        1 cccgactttt cacatagggg tgcccgagtc atacgggctg agattatacc catcgaacct
       61 gatccgggta atgccggcga agggaaaata aggtagaact aggaaataaa gggggcgtta
      121 cctctatgtg ctccctgatg tttaaacttt aattagttat taagatggaa cagattgttt
      181 caagtggaat cattgactct tacttcgaga agttgaagag caacttgtct gtggatgtag
      241 cgatcgtggg agggggacct tccggtatcg tggccgctta tttcttggcg aaagccggta
      301 agaaggtggc gttgtttgat cgtaagctgg ctcccggtgg aggtatgtgg ggcggcgcta
      361 tgatgttcaa cgatatcgtg gtgcaggaag aggctatgcc gattatcaag gaattgggcg
      421 taagctataa ggagggtgct aacggcacgt atatcatgga ttcggtacat accacttccg
      481 ctttgattta tcaggcgacg aaggcgggcg ctacgatctt taactgctat tcggtagagg
      541 acgtggtgtt tcataacgat gccgtagccg gtgtggtagt gaactgggct ccggtaatcc
      601 gtgaggggat gcacgtggat ccgttgacga tcatggcaaa ggctgtcttg gaaggtacgg
      661 ggcatgattg cgagattgcc cgtgtggtag cccgtaagaa tgatatccaa ttgaatacac
      721 cgaccggagg cgtgatcggc gagcgttcct tgaatgtgga gctgggtgag cagacgacgg
      781 tggagaacac gaaggagatc tacccgggat tattcgtttc cggtatggcc gctaacggcg
      841 taagcggtag cttccgtatg ggaccgatct ttggcggcat gctgatgagc ggcaagaagg
      901 ctgctgagtt gatctgcgaa aaacttggga attgaaaatt gagaattgag aattgaaaat
      961 taaagataca acaatcaata attttcaatt ctcaattcct aacggttttt ccttgtctca
     1021 agaataagaa tcccgttatg atcaatgccg tggataatcc cgtatagaat acggaaatga
     1081 aagaattcgg cagtaaatgg aacgtgcgga tcgtgatccc gaaagcgatc atgaagatca
     1141 tgataatcca acctttcacg tcgaaaaaag agaacgggca atgtttcccg tttttccggg
     1201 agatccgttc ggaatgttta tagaaaagcc gtttaaagac caaattgaag aaaagtaaga
     1261 aaacgatggt cgcttccccg atcttgaata accaataatg ggtatcgttt aaccatgtga
     1321 cgataccgat gcgtaagata ttgataccgg cgaaaatcca tacgcaaccg gcggtatata
     1381 ataatatctt tttatttact ccaaacttca tctatctttt tatttaccgc aaacttacaa
     1441 cattcatgta aaaaacggaa aaatatcctt atctttgtgc catgcgtgag aaaatgaaac
     1501 agaggattgt acaatacgtg gtgctgatgg ccggcatctt ggtattgctt tctgtggtta
     1561 tccctcacca tcatcaccgg gacgggatgc cttgttatca atccttgact gcggagcaag
     1621 cgcatggcga taaaagcact gatacgcatg attgcggttg cgacgggcat aacttggcct
     1681 atttcagtac gcatatttct cattttatgg atggagatgt ggatatacat ctgatgccgt
     1741 tactcgtctt atttgattac atttatccac ctgaaccggc gttttgcgga cagctccttg
     1801 atcacgagaa cgccccctac attgagtcgc tgcacgacac ttggatagtg agtgcctcgg
     1861 gacttcgtgc ccctcctatg tcttgatacc tcgtttgtga gagcgggtga ggacagactt
     1921 gcccctatct atttattatt aacgatatca agatttttta cacaatgaag aaaatatatt
     1981 tggtaggtgc gatgtgcgct tacctgtttg ccggttgtgc gggaaatgcg tcgcaagccg
     2041 gacacgatga gcataatcat gaattagagg ctcacgatca tgatcatgag ggacatgaac
     2101 acgaaggcca tgaccatgag catgaggccg gtggtaccca tcccggcgag attgtcttta
     2161 agaaggcttt agccgaggcc gttggtttgc agactgtaac ggttaatccc gctcctttca
     2221 cggatgtgat taagacgagc ggacgagtaa tggcggcgca aggggaggag tccgtgatcg
     2281 tcgctaccgt ccccggcgtg atctcgtttg gtagcttgcc attcgtggat ggtacggcgg
     2341 tacgcaaggg acaggccgtg ttgagtatcg cttccaacgc cctctctgat ggagacgtgg
     2401 cggcaaaggc taaattcgct tatgagacgg cgaaaaagga atacgagcgt atgcaagcct
     2461 tggtaggcga taagatcgta tccgccaagg atttcgagca ggcccgcttg aattacgaga
     2521 acgccaaggt cgcttatgag gcgatagcgg gaaaacagac ggcgaaaggc gtgtctgtag
     2581 tctctccctt gaatggttac ttgaagaaca tccaagtgaa agagggtgat tatgtatccg
     2641 taggccagcc tttggctacg atctcgcaaa acaatcgttt ggtattgcgt gcggacgtgt
     2701 ctgagaggta ttacaacgat cttcccatga tccaaaccgc taatttcatg actccgtatg
     2761 ataacgctct ctataaattg tctgatttgc gtggacggtt gttatcgtat ggaaaggctt
     2821 ccgatatgaa ctctttctat gtaccggtga ctttcgagtt cgataataaa ggagcggtta
     2881 tccccggttc tttcgtggag atctttttgt tgacaaagcc gatggagaat gtcttgagcg
     2941 tgcctgtctc cgcccttatc gaggagcagg gcgtttattc ggtatttatc cgtctggatg
     3001 aggaaggcta taagaagcaa tgggtgacgc tgggagcgaa taacggctcg gaggtacaga
     3061 tcctttccgg attgaaaccg ggcgatgagg tcgtgactcg tggcgcttac cagatcaagt
     3121 tgtcttccgc ttctaacgcg ataccggctc atagccatag ccattaatag gagggacgtt
     3181 gcatgttaaa taagataatt tattattcat tgcacaaccg gttggtaatc ttggtttgtg
     3241 cgctattgct gatgatctgg ggtacgtaca cggcgtttaa tacggacgtg gatgtgttcc
     3301 cggacttgaa cgccccgacg gtcgtgatta tgaccgaggc gaacggtatg gctcccgagg
     3361 aggtggaacg cttggtgaca ttccctgtgg agactgccgt gaacggtgcg atggacgtgc
     3421 ggcgtgtacg ttcctcgtct accaccggat tctccgtggt ttgggtagag tttgattggg
     3481 gtacggatat ttaccgggct cgtcagatcg tgtccgaaaa actggctgtc ttgggtgaga
     3541 gccttcccga gaacgtaggt aaaccgacct taggcccgca gtcatccatc ttgggtgaga
     3601 tgatgattct cggtttgacc gccgattcca cgtctttgtt ggacttacgt acgatcgccg
     3661 actggacgat ccgtccccgt ttgttgtcta cgggcggtgt ggcgcaggtt gccgtgatcg
     3721 gtggcgatat taaggagtac cagatattgt tggacccggc tcgtatgaag cactacggtg
     3781 tagggttgaa cgaggtgttg gatgtttgtc ggaatatgaa ccggaacgcc aatggtggtg
     3841 tattgtatga gtttgataat gagtatatca tccggggagt cttgtctacg tcgaaggcgg
     3901 aagagatcgc tcagggtgtg gtgaagaccg tgaatgagta tccggttacg ctgggtgata
     3961 tcgctacggt taagatcggc ggtaaaagcc cgaagctggg aaccgcttcc gagcggacaa
     4021 agccagccgt gctgattacc gtgactaaac agccggatac gagtacggag aagttgacgg
     4081 agaagctgga cgagattgtt gtcgatttgc ggaagaactt gccggtggat gtacatgtct
     4141 ctacggatat attccgccag agtcatttta tcgataactc tattaataat gtaaagaaga
     4201 gcttgtttga gggtagtttc ttcgtggtga tcgtcttgtt cctgttcttg atgaatatac
     4261 gtacgacggt gatctcgttg gtagccttgc cgttatcttt gctggtctct atcatcgtat
     4321 tgcactacat gggattgacg attaacacga tgagcttggg aggtatggcg atcgctatcg
     4381 gttccttggt ggatgacgct atcgtggacg tggagaacgt gtataaacga atccgggaaa
     4441 accggctctt gcctccggat cagcaacgct ctaccttgga ggtggtttac gacgcttccc
     4501 gtgaggtacg tatgccgatc ttgaactcta ccttgattat cgtggtgagc ttcgtgccct
     4561 tgttcttctt gagtggtatg gaaggccgta tgttggttcc gctgggtatc gcttttatcg
     4621 tggcgttgtt tgcttctacg gtggtggcgc ttaccttgac cccggtgctt tgtagctatt
     4681 tgctgaaccg taaagcgacg ggaatgaagg aactgcgtga ggcttggata gcccggaagt
     4741 tgaaggtggt gtataaacgg gctttggagt tagcgttggc ttaccagaaa tgggtgctag
     4801 gtaccacgat cgctttgttt gtggtcgcct tggtgatctt ctttcatttg ggacgtagtt
     4861 tcttgccccc gttcaatgag ggttctttta cgatcaacgt aagctcgctt ccgggaattt
     4921 ccttggacga gtcggatcag atcggacgcc gtgcggaagc gttgctgttg caagtgcccg
     4981 agataaagac tgtggctcgg aagaccggtc gtgcggaatt ggatgagcat gccttgggcg
     5041 tgaatgtttc cgagatcgag gctcctttcg aattgcaaga ccgtagtcgg gatgaggtga
     5101 tgaatgatgt ccgcaagaag ttatctacga tcagtggcgc taatatagag atcgggcaac
     5161 ctatttccca tcgtatcgac gctatgcttt ccggtacgga ggcgaatatc gctatcaagc
     5221 tgtttggtac ggacttgaac ctgatgttta cggtcggaaa ccagatcaag gccgctatcc
     5281 aaacgatccc gggtctggtg gacttgaagg tagagcaaca gatcgagcgt ccgcagttga
     5341 caatcacccc gaaacgtgag ttgctggcta aatatggtat tcccctgccg gagttcgagg
     5401 aatatatcaa tgtgatgttg ggtggagagg ccgtaagtca ggtgtacgac gatggcaaga
     5461 gcttcgacct gaccgtgaag acctccgacg ctagccgtgc cacgatggat gatattagta
     5521 atctgatgat cgatgccgcc ggacagaaag tgccgctaag ctacgtggcc gatatccgtt
     5581 ccgtgaccgg tccgaatacg atcaatcgtg agaatgtgca acgtaagatc gtgattagtg
     5641 ccaatgtatc ggaacgtgac ttgcgaagtg tggttaatga gatacaggat cgggtagagg
     5701 ctaatatccg tttgccggag ggataccata tcgaatatgg tggccagttc gagagcgagg
     5761 cggcggccag ccgtacctta ttgctgacgt cattgatgtc gttattggtg atcttcatgt
     5821 tactgtacaa tgagttcaag gacgtgaagg agagcggcgt gatcttgttg aacctgccgt
     5881 tggcgttgat cggtggcgtg attatcctat ggcttacttc cggcgagatc agtatcccgg
     5941 cgattatcgg tttcatttcc ttgtttggta tcgctacccg aaacggtatg ctgctgatca
     6001 gccactatac gcatttgcgt ggagagggaa tgggattgcg tgagtccgtg atacaaggtt
     6061 ccctagaccg tttgaacccg atcttgatga cggcgttgag ttccgccttg gcgttgatcc
     6121 cgttggcgtt gaatggcgat cttcccggga atgagatcca aagcccgatg gcgacggtga
     6181 tcttgggtgg tttattaacc tctacgttct taaacggatt catcatcccg attgtttatc
     6241 tgataatgaa caagaataaa gaataagttt tatgaaatca tatattatag tcgccgcctt
     6301 gtctgtattg acaggcggcc tttccgccca gacttctata gaggacgtgc tccggagcgt
     6361 ggaggcgaac aataaggatt tacaggcgaa cagccagttg gtccggtcgc agaagctgga
     6421 ggcgaagttg gataataatt tgccagaccc ttcggtctct tattcgcatt tctgggggaa
     6481 taaagaaggg atgggattca cgggcgagtt cgtggcttcc caaagctttg atttcccgtc
     6541 cgtatatgtc cggaagcata agctgacgaa ggcgaaatcc gcgggtttgg atcgtcaagg
     6601 gatggctttt cgtcagcaaa tcttgttgca ggtgaaagag gtttgcctag atttggtgct
     6661 gttgaaccag cagaagaacc tattggatac ccgtcttagg aacgccgagc aactttccgc
     6721 tttttatgcg actcgtttgg agaaaggaaa tgcgaatatc cttgagacaa acaagatcga
     6781 tctggaatta ttgaacgctc ggacagaggc ccggatgaac gagacttccc gtattgccaa
     6841 gctgcaggag ctagctaccc tgaacggcgg tatcgctatc gagtttacgg atacggttta
     6901 cgccttgccg gatagggagg tgctttcctt tgatgagctg cggacggagg cgatgcaatc
     6961 cgatccgcaa ttacagacct tgcgtagcga ccagacgaca gcccttcggc aggtgagcgt
     7021 gaataaggcg aaaggtctgc ccggctttga gttagggtat cgtatgaatc ccgcctcggg
     7081 tggagagcgt ttcaatggtt tcttggtagg aatcaccatc ccgttgttct cgaaccgtaa
     7141 taacgtgaaa caggcgaagg ctcaggcccg ctatacggag atgcagttgg agagcgcttc
     7201 tttcacggta gagaatgggt tgaggcagct atatgaccag tctgtctcct taaagaaatc
     7261 tatcgatgaa tataaggatg tgctgaaaag gcagaatagc ttggtcttgt tgaacaaggc
     7321 tatacaggcc gggcaaatct ctatgatcga gtatttcgtg gatgtgacga cctattacca
     7381 aagcgtgcaa aactacctgc aattgcaaaa ccaataccaa aaggtcatgg cgcaattgta
     7441 taagtatcga ttatgataag gaacacaact gtgttttctc ttgaacacag ttgtgtttat
     7501 ccacagatac agttgtgttt tctcacgaac acaactgtgt ttttacgttc tctaaggata
     7561 gcttaaagtc ccggatcaat tctttcatca cctcttccac ggataattcc tcccagaata
     7621 aagacgctac ctgtccgatc tctaactcgc cttcctttag gtcgccctca aagattcctt
     7681 tcttggcacg tcctttgccc aataactcac gtaattcttc cacggacgct ccccgggctt
     7741 ccgcttcttc cactgccgta gcgaaatctc cttttaccag acgggtagga gacagtttct
     7801 ttaataataa cttcgtatcg ccttccttaa gattcaagca tagtttcttg aaattctcgt
     7861 gtgccgagct ttctttggtt agggcgaaac gagtgcctat ctgtacgccg tcggccccta
     7921 gtgcgagtgc cgctagcatc gcttgaccgt ttccgatacc tcctgccgcc aaaaggggga
     7981 gggaggtcgc tttccggaca gcggggatca ggcacatcgt agttgtttcc tcccgtccgt
     8041 tgtgcccgcc tgcctcgaag ccttcggcaa cgatggcatc cactccggcc tcctcgcatt
     8101 tcgtggcgaa tttagagctg cttaccacgt gaacgaccgt catgtcatga tccttcaaat
     8161 actttgtcca tgttttcggg ttaccggcgg aggtaaatac gatcttcact ttttcctcca
     8221 ccaatatccg catcaaggta tcgatttccg ggtacatcag cgggacattc acgccaaaag
     8281 gcttgtcggt cgccgcctcg catttacgga tatgttcccg gagcacttcc gggtgcatgg
     8341 agcctgcccc gatcaatcct aatccaccgg cgttactaac cgctgaagct agccgccaac
     8401 cactacacca aaccattccc gcctgtatga tgggatactg aataccaaaa agactacaaa
     8461 ttcgattcat attatttctt gcgttaatct cgctaaaatt agtgaactat ttttattgga
     8521 acaacaattt ctttgtcgag gttgttgaat aggcatataa ctttaaaata taagagatat
     8581 gccagagaat ataatgaaaa cgttatggga tgagagcgat gatcttcacg atgagaccat
     8641 gtctaccaat tcggtattgt cggatgatta cacgtctaat gacattcaag atttacaaga
     8701 aacgatcgaa aatgaaaata tcgaggacgg tatagagagc gattcgattg aacattgaat
     8761 gaaagcatat tgggtccccg aagggaagat ctccctttgg ggatcttttt tgtgtgaatt
     8821 gtgaaaatct ttttccggat tctaaataat aacaatttga aatagaattg taacgcaaaa
     8881 cttcgttatc tttgtccatt gtaattctaa tataacaatg gcatgaataa aacgcttatg
     8941 gccgcaggtt tagcggttat tttgggagct tgttcctcct caaagaaaag cgatgtagcg
     9001 gaaggcgcta cacccaatcc gttttttgcg gagtatacga caccgttcgg ggtgcctccg
     9061 tttgaccaaa tagaggtggc tcattacaag ccggctcttt tgaaaggcat ggaagagcag
     9121 tcgaaggaga tcgaggcgat cgtggcaaat ccggatgcgc cgacattcga gaatacgatc
     9181 gtggccttag accaaagtgg cgagttgctt actaaagtaa tgtatgcttt cggtggccaa
     9241 tccagtgtga ataccacgga cgagatccaa gagctcgaac gtgagcttta tcccctttta
     9301 tccaaacatt cggatgatat cagcttaaat cccaagcttt tcgcccgggt gaaatccgta
     9361 tatgagaatc aggcgagctt ccatctggat aaggaacaga agaagctgtt ggaggaaacc
     9421 tataaaagct ttgtccgggg aggagccaat ctgccggagg ataagcaggc gaagttgcgt
     9481 gagctgaacg agaagatatc catgctccaa cttactttcg gacagaatac cctgaaagag
     9541 accaacgatt tccaattagt gatcgataat aaagaggact tatccggtct gccggaagac
     9601 gtgatcgtca aggcggcgca aacggcccaa gagaatggtc tggatggtaa gtgggtgttt
     9661 accctccata atccgagcgt gatgcctttc cttcaatacg ccgataagcg tgatttgcgt
     9721 gagaagatct tcaaggcgta tacgaatcgt ggcaacaata ataatgagaa tgataataag
     9781 gaggtcgtta agcagctggt tgccgctcgt ctggagaaag cccgattgat gggatatgag
     9841 gattatgccg ctttcgtatt ggaagagaat atggcgaaga acgagaagaa cgtgtatgac
     9901 ttgctcgata aaatctggcc gtctgctttg gcgaaagcga aagaggaatt ggccgatatc
     9961 aacgccgaga tcaagaagga aggcggtaat tacgaggccg agggctggga ctggcgttat
    10021 tatttcgaga aagccaagaa agcgaaatat aacttggacg agaacgagat gcgtccttat
    10081 tttgagttgg gacatgtacg tgagggcatc ttctatgtag ccaataaatt atatggtatc
    10141 acgtttaccg agatcaagga catcccgaaa ccggaccccg acgctctcgc tttcgagtgc
    10201 aaggataaag atggtacgca tctgggcgtg ctgtatatgg atttctttac ccgcccgggc
    10261 aaaggaggtg gcgcatggtg cggcggttac cgctcacaaa cgtataaaga tgggaaacgg
    10321 gtagccccgg tggttactac cgtatttaat ttcagcaaac cggcggaggg acaaccggcg
    10381 cttttgacgg ccgacgagac cgagaccgta ttccatgagt tcggtcatgc cttgcacggt
    10441 ttattctgcg atgttcatta ttatggcgtg tccgacgtgc ctcgtgactt tgtggagcta
    10501 ccttcgcaag tcgatgagca ttgggccgtt gagccggagg tattgaaagt gtacgctaaa
    10561 cattaccaga ccggcgaggt aataccgcaa gcccttgtag acaagatgat caagagtggc
    10621 aagtatggac aaggcttcgc tacgacggag tatctggccg cctcttatct ggatatggat
    10681 tatcatgtat tgaaagagat ccctgccgat ttggatattg agaaatttga ggcgaaggtc
    10741 ttgggcgatc gtggtctgat ccgtcagatt ccgtctcgct atcgctccac ttatttcgga
    10801 catacgatgg aaggtggata tacagccggt tattatagtt atatctgggc ggaagtgttg
    10861 gattgcgacg ctttccaagc ttataaggag acgggtaata tcttcaaccc ggaggttgcc
    10921 tctaaattcc gtaaatacgt actgaccccg ggcggcatcg acgacgctat ggacatgtac
    10981 gtgaatttcc gtggcaaaca acctagcatc gatccgctgt tggagaacag agggctaaaa
    11041 tgagcagaac aatttataac tcataaatca aaaaatcagt aaagatgaaa caattaatta
    11101 tggcagcagg attagccgtt atgcttactg cctgcggtac ttccgaaaag aagaccgtgg
    11161 agggtgagaa cccgttcttt gcggaatata ccaccccgtt tggagttcca ccttttgatc
    11221 aaatcaagtt cgagcactac aaaccggccc tattgcaagg catggaagag ggacgcaagg
    11281 agatcgaggc gatcgtgaat aacccggagg agccgacgtt cgagaatacg attgtcgctt
    11341 tggatgagca gggtgcgttg cttcggaagg tccagatcgt tttcggtgga cagaatagcg
    11401 tgaatacgaa tgatgagatg caggcgttaa gccgtgagat gtcgccgcta ttgtcaaaat
    11461 atagtgatga tatcaacttg aatccgaaat tattcgctcg tgtgaaggcg gtatacgata
    11521 agaaggatga gttgggtctc gataaggagc aaatgaagtt attggaggag acttataagg
    11581 acttcgttcg gggtggcgct aatctttccg ctgaggatca ggctaaattg cgtgagttga
    11641 atagcaagat ctccatgtta cagcttactt tcggacagaa tatgctgaaa gagacgaacg
    11701 ctttcaaatt ggtgatcgac aagcaggagg atctttccgg tctgcccgag accttgatcg
    11761 ctaacgccgc tcaagcggct aaggatgccg ggatggaagg caaatgggta tttaccttgc
    11821 agaacccgag cgtgatgccg ttcttgcaat attccgataa acgtgagttg cgtgagaaga
    11881 tgttcaacgc ttatatcaac cgtggtaata ataataatga gaacgataac aaggaagtgg
    11941 ttcgtgattt ggttgccgct cgtttggcga aagcgaagtt gatgggctat gatgattacg
    12001 cttctttcgt gttggaggat cgtatggcga aaagctcgga taaggtttat caattgttag
    12061 atgaggtttg gaagcctgct ttggcgaaag cgaaagagga attggccgat ataaacgccg
    12121 agatcaagaa agaaggtggc aatttcgagg ccgagggctg ggattggcgt tattatttcg
    12181 agaaggccaa gaaggctaaa ttcaatttgg atgagaatga ggttcgtcct tacttgaagt
    12241 tggataatgt tcgtgagggt gctttctatg tagctaataa gttatatggt atcacgttca
    12301 ccccgatccg taatattccg ttgccttatc cggaagcgca ggcttttgag tgcaaagata
    12361 aggatggctc tcatttgggc gttatttatt tcgatttctt ccctcgtgcc agcaagcgtg
    12421 gtggtgcgtg gtgtggttct tatcgtccgc aggcttataa ggatggcaag cgtgtggctc
    12481 cggtcgtaac gatcgtttgt aactttagcc agcccgctcc gggacaacct gcgttgttga
    12541 gcgctgatga ggcgaataca ttgttccatg agttcggtca tggtttgcac ggcttgttcc
    12601 gtgacgtgca ttactccggt gtttctggtg ttcctcgtga tttcgtggag ttgccttcac
    12661 aggttatgga gcattgggta ttcgagccgg aagtattgaa ggtgtacgct aagcattatc
    12721 agaccggcga ggtgatcccg gccgagttga tcgagaagtt ggataagagc ggtaagtacg
    12781 gacaaggttt cgctacgacg gagtatctgg cggcttctta tctggatatg gatttccatg
    12841 cggtcagtgg tgatgcggcg gataagaaag tgatcaagtt cgttgaccag acgaataatg
    12901 ttccggccaa cttgaatgtg atggatttcg agcaacagac gttaggccgt cgtggtttgc
    12961 tgaaacaaat cccttcccgt taccgtacga cttacttcaa ccatacgatg ggtggcggct
    13021 acaccgccgg ctattatagc tacatctggg ctgaggtatt ggattgcgac gctttcgagg
    13081 cattcaagga aaccggcgac atctttaatc aagaatgtgc cgataaattc cgtaaatatg
    13141 tcttgacccc gggcggtatc gacgacgcta tggatatgta caagaatttc cgtggcaagg
    13201 aaccgggtac ggatccgttg ctgaagaata gaggactgaa ataatctaga aatggagatt
    13261 ttataaaggc ggaccggttg gttcgccttt ttttgtatat gctcaacctc ccggatctgt
    13321 attacatttg ctaagtttta tcacgaaaaa atagcgatag tatggagaaa aaggatttag
    13381 tagaagggat gaggttgtat atctataaat tgcgtgtgga tgggcgttat tccacggcga
    13441 agagctatca ggatgcattg aactcattca tgcggttttg tgggttggag gtaattccct
    13501 atatctatgt caataaggag aaccttcggc gttatcaggc ctttttgttg aataaaggat
    13561 gtacatggaa cacggtgtcg acctatatgc gtcggatccg ttgtgtgtac aacatggcgg
    13621 tggaggaagg gttggccccc tatatccctt atttatttaa gggagttttc acgggtatag
    13681 agagcaaacg caaaaaggcg ttaccacagg atttattacg ttctctgatg acggcctcat
    13741 tagatgatcc ggaactgaga aaaacacggc aggcattgtg cctgatgttc cagttttgcg
    13801 gtatggcatt cgtggatttc gctcatctga aaaaggagaa tgtccggggt ggggttttgg
    13861 aatataaacg ccagaaaacg ggtactccga tgcttataga ggtacaatct accgcatggg
    13921 agtcgctgag ggaactgtca agtgatgtag gtaaggactc accctatttg tttcctttct
    13981 tgaaagggat aaaagtggga aaagaagcct acaaggagta cacttccgct ttggcccatt
    14041 ttaaccggaa tttgaagagg ttggcgagag cctgcggtgt gtctatcccg atcacctcat
    14101 attcgatccg tcattctttt gcgatgattt tgaaggaaca ggatgtcccg attgagatga
    14161 tcagcgaact attgggccat aaatcgatca agactacgca aatctatttg aaaagtttct
    14221 cgttggaaaa gatgtctgcg gtgaataaaa tttgttttga gagtgtgtac aatcatgtac
    14281 cgaaagtagg gtaaagggag taggctactt ggggagtagc gtattctttc acggcgcaaa
    14341 tgtagtaaaa aataactaaa aacaagcaaa caaatgcgct tgtttactca ttgtaggcgt
    14401 ttgatcctct ctattctttg attttcttat tttatcctag acgtatagac atggtgatgc
    14461 gggtgaaatg acctcttgtt cccggtatca ttccaccatg ccttataacc tgtgtgtatt
    14521 cctgtagaga cggggcacgc cccgtctcat cccctccaaa tggtaactta aagctactat
    14581 cagacagtgg gagacggggc gtgccccgtc tctacaaccg ggtgataacc gttctcgcac
    14641 cttttaggct actccccaag tagcctaaga tttcgagaga tggtaatttt cagtaatgcc
    14701 atattttgaa atataaagca ctgtttatca agataatata aaagattctt ggtagggctc
    14761 tgaattgccg tggggtctgt tttcgggcca cgggataacc actggaaaag ataatcatag
    14821 agatggatat attgacaggc aagtgctcgg ataggttcat ggcgcatgtt ctgaagcgac
    14881 gtgaccagga ggccgtccgc tggtacgtgc tcacgctccc taccgccggt ggcgggcgtg
    14941 acaggatcag cccctcgaag gggctggacg ctgagctttc ccgccgtgag cgtcgtggtg
    15001 aggcgttgtt cgagtatttc tccccctcgt atgtcgaggc gaggaaggtg ggcggcaaga
    15061 tggtcaacac gaaacggccc ctgttgtaca actacgtgtt cgtccacgcc tcggaggacg
    15121 agatcttccg cctgaagcgt acgcttcccc tgtataattt cctcccccgg gtttcctccg
    15181 gcgggcggtc ttatttcccg tacctctcgg atcgtgagat ggataccttg cgttgggtcg
    15241 cggcttctta ctccaacgag cttccggtgt acgtgccaga tagcggtcgc ttgttgaaag
    15301 gcgaccgtgt gcgtatcacc tccggccctt ttaccgacat ggaggccgag gtggtggtac
    15361 agccgggcgg tggccataag gacgtgatgg tgcgtatcct cgattgcatg tgggttccct
    15421 tgttcgaggt gaggcgaggc gagtatgagt tgatcgagct gaacacgggg ggcaagcacg
    15481 tgtataccca tttggacaac gaccgtctgt cggagggctt gcacgatgcc ttgggccgtt
    15541 accacgccag aggcgtggta acggatgagg atgcccgtct ggcccgtgag gtcctgcgtg
    15601 gctacgcctc tctccgtggt gagaccgacg tgatccgttg caagctttac tctttgctcc
    15661 ttccagccta tctgcttttg ggcgagtcgg atgagttcga tcgtttgcac gccacgatgc
    15721 gcagcatgct cccggtgata aaagcggggc aatcccgtgc cttgttgctg gtcacgctgt
    15781 acggctgtac ggacagcagc ctctacca
//
LOCUS       DBMDTB010000093        15189 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_1235_length_15189_cov_11.717192, whole genome shotgun
            sequence.
ACCESSION   DBMDTB010000093 DBMDTB010000000
VERSION     DBMDTB010000093.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 15189)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 15189)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15189
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1235_length_15189_cov_11.717192"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..1221
                     /locus_tag="ACZPB4_13315"
     CDS             <1..1221
                     /locus_tag="ACZPB4_13315"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hybrid sensor histidine kinase/response
                     regulator transcription factor"
                     /protein_id="HIR1099229.1"
                     /translation="MIIECNVKSFYAFIDKEACTKILSNLLSNAIKYARSKIIVRFET
                     QDGERFTIDIMNDGKPISEEIKEKIFEPFYRDDSSIHKSGTGLGLPLARSLAEMHEGS
                     LTLEESPTGLIIFRLRLPVNQPNSLKLEEEKAEVLTNPASERKYVTQESRPTVLVVED
                     NTEMLHFIGQEINVHYNVVTAGNGEEAIARLQEYGIQLIISDIMMPVMDGFTLLKKIK
                     TNLEFSHIPIILLTAKNTLQSRMEGLELGADAYIDKPFSMDLLLTQVTNLLNNRSNMR
                     AYYFNSPIANIKSMAYTKADEKFLKKLNDIIDSHINDVNLDVDMIADLMNLSRPTLYR
                     KINGLSNVTPNELIKISRLKKAAELILQGDMRIYEIAEAVGFNSQSYFSRAFSKQFNM
                     SPSQYAKENNIELK"
     gene            complement(1226..2068)
                     /locus_tag="ACZPB4_13320"
     CDS             complement(1226..2068)
                     /locus_tag="ACZPB4_13320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HIR1099230.1"
                     /translation="MWDQKIPSYIYGKQNIVRLILWTALFALVFINIYKPFSSTSWYK
                     VSEFKFFVFSSLIILTGVLVVVLSRIILFHWGKRHAITVRTYAIWIVLEIFFMSLFYT
                     IYTLVLNPEREYMEVFNDSAVNTSLVLLLPYSVLHLYFSYKEKERQLRLLEENQTEAA
                     VRQSVFSFYDEKNELRLSVKRSNLLYLESADNYVCIWYLNKGQLTKFMLRNSLKAIEE
                     SLADTNVLRCHRSFMVNFDQVKVIRREKEGVYLELGIEKVPDIPISKTYSEKVTRWFQ
                     TYSS"
     gene            2248..3393
                     /locus_tag="ACZPB4_13325"
     CDS             2248..3393
                     /locus_tag="ACZPB4_13325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6051 family protein"
                     /protein_id="HIR1099231.1"
                     /translation="MDISLRTKQLNSLFSYDKKTELEESHLEIIPFRFTQTRGASEID
                     EFQKGLTPTGFCPMTDDRIQENKSFSYAIFTPSGRKKNNEAIILLHGLNERTWEKYLT
                     WAEYLTHTTGKPVILFPIAFHMNRTPGLWANPRAILPWVSKRKEEVANVTNSTFANVA
                     LSSRLSQNPLRFYASGRESVYNMWQLVHEIKNGEHPLFKEDTSINLFAYSIGALLSQV
                     LLLANPDKMFTDTRLFMFCGGSIFSEMDGNARDIMDKEAFAKVRHYFRHDFLENRTLP
                     TSFKNDFLEQAFKAMVREDVLRDYRESFFQRACDRIRAISLKKDIVMPTGGVIKALGK
                     ASGKILEELDFPFAYSHQIPFPTHSRIDPGLINQAFHSIFTRAAAFL"
     gene            complement(3503..3576)
                     /locus_tag="ACZPB4_13330"
     tRNA            complement(3503..3576)
                     /locus_tag="ACZPB4_13330"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3540..3542),aa:Ile,seq:cat)
     gene            complement(3654..4779)
                     /gene="prfB"
                     /locus_tag="ACZPB4_13335"
     CDS             complement(join(3654..4715,4717..4779))
                     /gene="prfB"
                     /locus_tag="ACZPB4_13335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005942570.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HIR1099232.1"
                     /translation="MITSDQLHDVLERDKALRGYLDIDSKTIQLEEEELRTQDPGFWE
                     DAKRAEVQMKKVKELKKWIELYGEVHAAAEELELAYEYVKEEIITEEEVDAAYKKALH
                     LLEDLEFRNMLRDEADQMSCVLKINSGAGGTESQDWASMLMRMYQRWAENNGYKISIA
                     NYQEGDEAGIKTVTIDIEGDYAYGYLKSENGVHRLVRVSPYNAQGKRMTSFASVFVTP
                     LVDDTIEVKVEAAAISWDTFRSGGAGGQNVNKVESGVRLRYQFKDPYTGEEEEILIEN
                     TETRDQPKNRENAMRQLRSILYDKELQHRMAEQAKVEAGKKKIEWGSQIRSYVFDDRR
                     VKDHRTNYQTSDVNGVMDGKIDDFIKAYLMEFAGEESAEK"
     gene            complement(4842..6647)
                     /locus_tag="ACZPB4_13340"
     CDS             complement(4842..6647)
                     /locus_tag="ACZPB4_13340"
                     /EC_number="6.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015645 - fatty acid ligase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-dependent synthetase/ligase"
                     /protein_id="HIR1099233.1"
                     /translation="MIYYHFAELIHRQAEKYGNRTALKHRDNATGKWLKISWREFSDK
                     VMLTAKAMAEFGIKVQENIGVYSQNMPQCLYTDFGAYGNRVVSIPMYATNSPGQIEYI
                     INDAKIRTLFVGEQLQYNNAFKVQKDSKYLERLVVFDPAVKMNPEDKTSIYFDDFLRL
                     GDNAHAESTVKIRMTEAVPEDLATIIYTSGTTGESKGVMLPHSCYLEAMRIHDVRLPL
                     VTDKDLSMSFLPMTHIFEKAWCYYCLHKGVTIAINQDPKMIQKTLPEVHPTLMCNVPR
                     FWEKVYAGVHEKINSASPAMKKIFLDAIETGRRYNLEYKNKGIPAPCSLKLKFQFYNK
                     TVFTLLKKVLGIERGRFFPVAGAPLSDTINEFLQSVNIPIAYGYGLSETTATVCFYPE
                     IGFQFGSIGEVMPGVQVKIDPGNNEILVKGKTVMSGYYNKPEETKRAFTEDGFFRTGD
                     AGRLEGNTLFFTERIKDLYKTSNGKYIAPQAIEMVMSGDNYIEQIAVIGDQRKFVSAL
                     IVPAYPLLEKYAGEKGISFESREELVKNKDIIRFIEARVEEHQKNLASYEKIKRFTLL
                     PEPFMMGCELTDTLKLRRPVVLQKYATEIEAMYEE"
     gene            6835..7161
                     /locus_tag="ACZPB4_13345"
     CDS             6835..7161
                     /locus_tag="ACZPB4_13345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009860753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HIR1099234.1"
                     /translation="MNAENVKSQMRKGTLEYCILLLLKKEPAYTSDIIQKLQEAKLIV
                     VEGTLYPLLTRLKNSELLSYQWIESTQGPPRKYYQLTEKGELFLGELEASWQELNDTI
                     NHIRNN"
     gene            7174..8286
                     /locus_tag="ACZPB4_13350"
     CDS             7174..8286
                     /locus_tag="ACZPB4_13350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HIR1099235.1"
                     /translation="MKKTLTVNLGGTVFHIDEDAYQLLDKYLSNLRIHFRKEEGSDEI
                     MDDFEMRISELLNERVRLGYEVITIEQVEEVIKRMGKPEEIFEEEEKSTDHEDNYRTQ
                     QQETHTQTTKKRLMRDPDNRILGGVAGGFAAYMDWDPTAVRIVLFLLMFFYGITVPLY
                     FLLWIIVPMARTATEKLEMRGQSVTVENIGKTVTDGFEKVSNNVNDFISSDKPRNFFQ
                     KLADVFVLVIGFILKFFIILAGIILLPPLVLVVFILVVVTFALLMGGAGFIYNLSPFG
                     ADLINGAPLSMAIMGCIGTILFIGIPIFSLIYAICSQLFKVRPLPTQARWILLALWLI
                     SFILCGVYIHQSGMLYDWHNYWNGVHDWNRHAVWLP"
     gene            complement(8528..8923)
                     /locus_tag="ACZPB4_13355"
     CDS             complement(8528..8923)
                     /locus_tag="ACZPB4_13355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HIR1099236.1"
                     /translation="MATIFSRIVAGEIPSHKVAEDDEFFAFLDINPVALGHTLVIPKK
                     EVDYIFDIDDPMLGRMVAFAKRVARAQETAIECKRVGLAVMGLEVPHAHIHLIPITKE
                     SDMYFGGKKLAVSQEELAEIAAKIRKEFK"
     gene            complement(8938..9408)
                     /gene="greA"
                     /locus_tag="ACZPB4_13360"
     CDS             complement(8938..9408)
                     /gene="greA"
                     /locus_tag="ACZPB4_13360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008147156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0070063 - RNA polymerase binding [Evidence
                     IEA];
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HIR1099237.1"
                     /translation="MAVSYMTKDGYDKILAEINYLETVKRPEISAQIAEARDKGDLSE
                     NAEYDAAKEAQGIMEAKLAQLKGLISNARLIDESRVKTDEVQILNKVKIKNTKNNAVM
                     TYTLVSDSEANLKEGKISVSTPIAQGLMGKKVGDVVEIRVPSGLMTFEIMDISI"
     gene            complement(9606..10763)
                     /locus_tag="ACZPB4_13365"
     CDS             complement(9606..10763)
                     /locus_tag="ACZPB4_13365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016209 - antioxidant activity [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin domain-containing protein"
                     /protein_id="HIR1099238.1"
                     /translation="MKQISTNLLAVLCVMLLLFTACKKNSDFTVEGVVSGADGQMMYL
                     ENVGVSTVELMDSVKLTAAGKFSFTKPRPAFPDFYRLRLNNQLINFSVDSTETISFVA
                     DAGTFATSYSVEGSENCKAIKNITLAQLDANQAIHRLRKESESGLLADSVYSRQVLEA
                     AEAYKDVARKYIYSAPMSAAAYFALFQQIDGLLFFDLYDKNDSKAYGAVATSFDHYYP
                     ESPRAKHLYNLALQSIKVIRSQRPMDLDKVEKKEVSFLDIELPDVHGENTKLSSVATG
                     KVVLINFTAYMSEWSPALNMEFGDLYTRYHDKGLEIYQISLDNDVHFWKNAASNLPWT
                     CVRDPQSVYSQTAALYNVKQLPAIFILDRKGNLVKRVDDVKKLEADIKSVL"
     gene            10967..13207
                     /gene="pnp"
                     /locus_tag="ACZPB4_13370"
     CDS             10967..13207
                     /gene="pnp"
                     /locus_tag="ACZPB4_13370"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HIR1099239.1"
                     /translation="MLNPINKTIELGDGRTITIETGKLAKQADGAVTVRMNNTVLLAT
                     VCAAKDANPGVDFMPLQVEYKEKYSAFGRFPGGFTKREGKASDYEILTSRLVDRALRP
                     LFPDNYHAEVYVNIILFSADGEDLPDALAGLAASAALAVSDIPFNGPISEVRVARTDG
                     KYIVNPTSAELEKADIDIMVAATIDNIMMVEGEMNEVQESEMLEAIKVAHEAIKVQCK
                     AQLELSEACGKLVKREYCHEVNDDELRKDVHDKCYAKAYAVATSGSGKHERSEAFEKI
                     VEEYKAQFSEEELTDEKLEMIGRYYHDVEKEAMRRAILDEGKRLDGRKTTEIRPIWIE
                     TDCLPGPHGSAIFTRGETQSLSTVTLGTKSDEKMIDDVLNHGYERFLLHYNFPPFSTG
                     EAKATRGVGRREIGHGNLAHRALKRMIPDNYPYVVRVISDILESNGSSSMATVCAGTL
                     ALRDAGVPMKKPVSGIAMGLISENKGTNYAILSDILGDEDHLGDMDFKVTGTKDGITA
                     TQMDIKVDGLSYEILENALAQAKEGRMHILGKILEAQPEAREDLKPHAPRIETMIIGK
                     EFIGAVIGPGGKIIQGIQEKTGATVSIDEVDGVGKIEISGTNKATIDAAVKAIKGIVA
                     VPEIGEVYEGKISSIMPYGAFVEFMPGKDGLLHISEIDWKRLETVEQAGLKEGDTVSV
                     KLVDIDPKTGKFKLSRKVLLPKPEGYEERPPRPERGERGPRPDRGDRGPRQDRGDRGP
                     RREYRD"
     gene            complement(14104..14700)
                     /locus_tag="ACZPB4_13375"
     CDS             complement(14104..14700)
                     /locus_tag="ACZPB4_13375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008781081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099240.1"
                     /translation="MKKILILSCLFLFFVSSCSNQEEVIVGDGLDYDNMSEEDLRKCA
                     EANGAITWNQFIELMGEFMESEQSPLIETKATSETFSVTGYDNTFLVEENKKVLINKS
                     PTNIPTGYYFCDIYIVRKMVTLPDGTLGVTKESPKCGFDPNSIGGGLRGCAVDGQTGN
                     RFYMKTAAYQVKYDMLGRQWNRWDPSLNALAWNYAYIY"
     gene            complement(14776..>15189)
                     /locus_tag="ACZPB4_13380"
     CDS             complement(14776..>15189)
                     /locus_tag="ACZPB4_13380"
                     /inference="COORDINATES: protein motif:HMM:NF023021.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3244 domain-containing protein"
                     /protein_id="HIR1099241.1"
                     /translation="EQCFSPESNLIGYFCSQKMNGMKRFLFLTLLSCVCLWTHTVAGR
                     EHKNERDEEEERSISPNPVEVKIVNDGIMFYFMKPLDNVFIQIVDDSGMLVYEESVPL
                     STSQSYCISMQGLLFKPYLIRVEGDNIYEEFFILF"
BASE COUNT         4304 a         3680 c         3145 g         4060 t
ORIGIN      
        1 atgattatcg agtgtaacgt gaaatctttc tacgccttta tcgataagga ggcttgcacg
       61 aagatactca gcaacctcct atcgaacgct attaaatacg caagaagcaa gatcatcgtc
      121 cggttcgaga cgcaagatgg cgagcgattc acgatcgata tcatgaacga tggaaagccc
      181 atctcggagg agataaaaga aaagatcttc gagcctttct accgggatga ctcctctatc
      241 cataaatccg ggaccgggct tggactaccc ttggcccgtt ctttagcgga gatgcacgag
      301 ggatcgttga cgttggagga atctccgact gggcttatca tctttagatt acgtttgccg
      361 gtgaaccaac cgaactcatt aaaactagag gaagagaaag cagaggtcct gaccaaccct
      421 gccagcgagc ggaaatatgt cacccaagaa tcccgcccga cggttctcgt ggtggaagat
      481 aacaccgaaa tgctccattt catcggtcaa gagatcaatg tccattacaa tgttgtcacc
      541 gccggtaatg gcgaggaggc gattgcccgt cttcaggaat atggcatcca attaatcatc
      601 agcgatatca tgatgcctgt catggatggt ttcaccttat tgaaaaagat aaagactaat
      661 ctggagttca gccatatccc gatcatcctc ctgacggcta agaacacctt gcaatctcgc
      721 atggaagggc ttgagctggg ggcggacgct tacatcgaca aacctttctc catggatcta
      781 ttgcttaccc aagtgacgaa cctgctgaac aaccggagca atatgcgtgc ctattatttc
      841 aactcgccga ttgccaatat caaatccatg gcttacacga aggcggacga gaagttcttg
      901 aagaaactga acgatatcat cgacagccat ataaacgacg tgaacctaga cgtggacatg
      961 atagcggact tgatgaatct aagccgtccg accctttacc gtaaaatcaa cggcctgtcg
     1021 aacgtaacgc ccaacgagtt gatcaagatc agccggctaa agaaagccgc cgagttgatc
     1081 cttcaaggcg atatgaggat ttacgagatc gccgaggcgg ttggtttcaa ctcgcaatcc
     1141 tatttcagcc gggccttctc caagcaattc aacatgagcc cctcgcaata cgcgaaagaa
     1201 aataatatcg aattgaaata gcccgctagg aagaataggt ctggaaccaa cgagttacct
     1261 tctcgctata cgtcttggag atcgggatat cgggtacttt ctcgatcccc agctccagat
     1321 aaacaccctc cttctccctg cggatcacct tcacttggtc gaaatttacc atgaaagaac
     1381 gatggcaacg gagtacattc gtatcagcga ggctctcctc gatcgccttc aaggagttgc
     1441 gaagcataaa cttcgtgagc tgccccttat tcagatacca gatacaaacg taattatccg
     1501 ccgattcaag gtacagcagg ttacttcgct tcacggaaag gcgcaactcg ttcttctcgt
     1561 catagaaaga gaaaacgctt tgccgaaccg ccgcttccgt ctggttctcc tccaacaatc
     1621 gcaattgtcg ctctttctct ttataagaga aatacaggtg cagcacggaa taagggagca
     1681 ataaaaccag actggtattc accgccgaat cgttaaaaac ttccatatat tctcgttccg
     1741 gattcagtac caacgtataa atcgtataga aaagcgacat gaagaatatc tccagcacga
     1801 tccagatcgc ataggtccgg accgtgatag catgccgctt cccccaatgg aacagaataa
     1861 tacggctcaa gacaaccacc aatactcccg tcaagataat caagctggag aatacgaaga
     1921 acttaaactc cgagaccttg taccaagagg tggagctaaa cggcttgtag atgttgataa
     1981 acaccaacgc aaacaaggcc gtccacaaaa tcagcctcac gatattctgt ttaccgtata
     2041 tgtaacttgg tattttttga tcccacattc ccatcttttt gcctctattt tggaacaaat
     2101 gtaatcattt tcccagacga aattcacccc tctataaaag atttcacccc taaataacac
     2161 tttatgtccc caacaaagtc cgtttaaacc atttattttg aagagatgtt tttctattgt
     2221 ttgtttgcag taaaaaatca gaggattatg gatatttcac ttcgtactaa gcaactgaac
     2281 agtcttttct cttatgacaa aaagactgaa ttggaagaga gccatctgga gatcatcccg
     2341 tttcgcttca cccagacccg tggcgccagc gagatcgacg agttccagaa gggacttacc
     2401 cccaccggat tctgtccgat gaccgacgat cgtatccaag agaacaaatc tttctcgtat
     2461 gccatattca cgccctcggg acgtaaaaag aataatgagg cgattatcct gttgcatggc
     2521 ctgaacgagc ggacttggga aaaatacctc acatgggcgg aatacctcac ccatacgacc
     2581 ggtaagccgg tcatcctgtt cccgatcgct ttccatatga accgtacccc gggattatgg
     2641 gccaatcccc gtgcgatcct cccttgggta agcaaacgca aggaggaggt agcgaacgtg
     2701 acgaactcca ccttcgccaa cgtagccctc agcagccggc tatcccaaaa cccgttacgc
     2761 ttttacgcct cgggcagaga gtccgtttat aatatgtggc aattggttca tgagatcaag
     2821 aacggcgagc atcctttgtt caaggaagat acgtccatca acttattcgc ttattccatc
     2881 ggggcgttac tctcgcaggt cttgttatta gcgaatccgg acaagatgtt tacggacacc
     2941 cgtttattca tgttttgcgg tggctccatc ttcagtgaga tggatggcaa cgcccgtgat
     3001 atcatggaca aggaggcgtt cgccaaggta cgccattact tccggcatga tttcttggag
     3061 aaccgtacgc ttcccacctc gttcaagaat gattttctgg agcaagcctt taaggccatg
     3121 gtacgtgagg atgtgttacg agattaccgg gagtcgttct tccaacgggc ttgcgatcgt
     3181 attcgggcga tctcattgaa aaaagatatc gttatgccta ctggcggggt gatcaaggct
     3241 ttaggaaaag cgtccggcaa gatattggaa gagctggatt tcccgttcgc ttactcccat
     3301 caaatcccct tcccgacaca ctcccgtatc gatccgggcc tgatcaacca agcctttcat
     3361 tccatattca cgagggcggc ggcgtttctc taaagagatc acaaattgtg acctcaaaca
     3421 ctcatattct tttttagttc atgcaggtac aataaaaaat cgctaaataa ctaatattac
     3481 gttatttagc gatcatccat cgtggtccca cttgggcttg aaccaaggac tccctgatta
     3541 tgagtcaggt gctctaacca actgagctat aggacctgtt cagagctagg ctctgaaatc
     3601 gggtgcaata ttacgattta ttatcgagat atgcaaatgt taaagggaaa aacttatttt
     3661 tctgcgcttt cttctccggc gaactccatc aagtatgctt tgatgaaatc gtcgatcttt
     3721 ccatccatca caccgttcac gtcggaagtc tggtagttcg tacgatggtc ttttacgcga
     3781 cggtcatcga atacgtaact acggatctgc gaaccccact cgatcttttt ctttccggcc
     3841 tccaccttgg cctgctcggc catacgatgc tgcaactcct tatcgtaaag gatggaacgc
     3901 aattgacgca tagcgttctc acggttcttg ggttggtcgc gagtctcggt attctcgatc
     3961 aagatctctt cttcctcgcc tgtatacggg tccttgaact gataacgcaa gcgaactccg
     4021 gattccacct tgttcacgtt ctgtcctccg gcgccgcctg aacggaacgt atcccaagag
     4081 atagctgccg cctctacctt tacctcgatc gtatcatcca ccaacggggt gacgaatacg
     4141 gaggcgaaag aggtcattcg tttaccttgg gcgttgtaag gagatacacg taccaaacga
     4201 tgcacgccat tctcgctctt tagatagcca taggcgtaat cgccctcgat atcgatcgta
     4261 accgtcttga taccggcctc atccccttcc tgatagttgg cgatagagat cttataaccg
     4321 ttattctcag cccaacgctg atacatacgc atcaacatgg aagcccaatc ttggctctcg
     4381 gtaccaccgg cacccgagtt gatcttgagc acgcagctca tttgatcagc ctcgtcacga
     4441 agcatattgc ggaactccaa gtcttccagt aaatgaaggg ccttcttata agccgcgtcc
     4501 acctcttcct cggtgataat ctcttccttt acatattcgt aagccaactc tagctcctca
     4561 gccgccgcat gtacctcacc gtaaagctcg atccatttct ttagctcctt tactttcttc
     4621 atctggactt ccgcacgttt ggcgtcttcc cagaaaccgg ggtcttgcgt acgtagctcc
     4681 tcctcttcta actgaatggt cttgctatcg atgtcaaaga taccccctca gcgccttatc
     4741 gcgctccaac acgtcatgta gttggtctga tgtgatcata tgttcttttc ttttttaaat
     4801 ttaccgcgaa gataagaaat agttgatagc cgacaaactc gttattcctc gtacatcgcc
     4861 tctatctcgg tagcgtactt ctgcaatacg accggacgtc gcaactttag cgtatccgtc
     4921 agctcgcatc ccatcatgaa gggttccggc aacaaggtaa agcgcttgat cttctcgtaa
     4981 gaagccaagt tcttctggtg ctcctctacc ctagcctcga tgaaacgaat gatatccttg
     5041 ttcttcacca actcctcccg gctctcgaac gagatgcctt tttccccggc atacttctcc
     5101 aacaatggat aagccggcac gatcaaggcg ctcacgaact tacgttgatc gccgataaca
     5161 gcgatttgct cgatataatt atcaccgctc atcaccatct cgatcgcttg cggggcgata
     5221 tattttccgt ttgaagtctt atacaaatcc ttgattcgtt ccgtaaagaa taacgtatta
     5281 ccctccaaac gaccagcgtc gccggtacgg aagaaaccat cttcggtgaa agccctcttc
     5341 gtctcttccg gtttattata atatccggac atcacggtct tgcctttcac caagatctcg
     5401 ttattccccg gatctatttt cacttgaact cccggcatta cctcaccaat agaaccaaac
     5461 tggaatccga tctccggata gaaacaaacc gtagccgtcg tctcgctcag tccatagcca
     5521 taagcgatcg ggatattcac ggactgcaag aactcattaa tcgtatccga taacggagcg
     5581 cccgccaccg ggaaaaaccg tccacgctca atacccaata ccttcttcaa taaggtaaaa
     5641 accgttttat tgtaaaattg gaacttcaac ttcagactac acggggccgg aataccttta
     5701 ttcttatact ccagattata ccttcgccca gtctcgatag catccaagaa aatcttcttc
     5761 atggccggag aggcggagtt gatcttctcg tgtacgcccg catacacctt ctcccagaaa
     5821 cgaggcacat tgcacatcaa agtaggatga acctccggca atgtcttctg gatcattttc
     5881 gggtcttggt tgatagcgat cgtaacccct ttatggagac aataatagca ccaagctttc
     5941 tcgaagatat gagtcattgg caagaaactc atggatagat ccttgtcggt taccagaggc
     6001 agacggacat catgtatccg catcgcctcc agatagcaag aatgaggaag cattacgcct
     6061 ttcgactcac ctgtcgtacc ggacgtatat ataatggtag ccagatcctc cggaacggct
     6121 tccgtcatac gtattttcac cgtgctctcc gcatgcgcgt tatcccccaa gcgcaagaaa
     6181 tcatcaaaat aaatggacgt cttatcttcc ggattcatct tgaccgccgg atcaaagaca
     6241 accagacgct ccagatactt agagtccttc tgtaccttga aagcgttatt atactgcaat
     6301 tgctcaccca cgaacaacgt gcggatctta gcgtcattga tgatgtactc gatttgtccc
     6361 ggagaattcg tcgcgtacat cgggatggaa accacccggt taccatacgc accgaagtcc
     6421 gtatataaac actgaggcat attctgggaa taaaccccga tattctcttg tacctttatc
     6481 ccgaactcag ccatcgcctt ggccgtaagc ataactttat cggaaaactc cctccaagaa
     6541 atcttcaacc atttccccgt agcgttatct ctatgtttca acgctgtacg gttcccatat
     6601 ttctctgcct gacggtgtat taactcggcg aaatgataat aaatcataat tccttatttt
     6661 gaattgatac cgcgaaagta cgcttttctc ttctaaaaga cacgacatca gtcctttttt
     6721 tacacataat tgctcttttt gtgcaagtat tcggttaaat aataataatt catagtagca
     6781 tgtattgcat agtacatatg taatacatac atttgtagca taaaattaaa agagatgaat
     6841 gcagagaacg taaaatcaca aatgaggaaa gggacgctgg aatattgcat cctcctgctt
     6901 ctcaaaaagg aacccgctta cacctctgat atcattcaga agttacaaga agcgaagttg
     6961 atcgttgtgg aaggcacttt atatcctctt ttaacccgac taaaaaatag cgagctatta
     7021 agttatcagt ggatagaatc tacgcaagga ccgccacgca agtattacca actgaccgag
     7081 aaaggagaac tattcctcgg cgagctggag gcttcatggc aggaactaaa tgatacaata
     7141 aaccacatca gaaacaatta aaacgaaaga gtgatgaaga agacacttac tgttaatctg
     7201 ggaggcacag ttttccacat tgacgaagac gcataccaat tattagacaa atatctgtct
     7261 aacctgcgca tccacttccg caaagaagag ggttcggatg agatcatgga tgatttcgag
     7321 atgcgtatct cggaacttct taacgagcgt gtccgcttag gctacgaggt catcacgatc
     7381 gagcaggtag aggaagtgat caaacggatg ggtaagccgg aagagatttt cgaggaggaa
     7441 gagaaaagca ccgaccacga ggataattac cggacacaac aacaggagac tcatacccag
     7501 acgaccaaga aacgcttgat gcgtgacccg gataaccgta ttctgggagg tgtcgccgga
     7561 ggtttcgccg cctacatgga ttgggacccg actgccgtac gtatcgtgct tttccttctg
     7621 atgttcttct atggaatcac ggttccgctt tactttttgc tgtggatcat cgtaccgatg
     7681 gcacgtacgg cgaccgagaa actcgagatg cgcggacaaa gcgtgacggt ggagaatatc
     7741 ggaaagaccg tgacagatgg attcgagaaa gtcagcaata acgtgaacga ctttatcagc
     7801 tcggataagc cgaggaactt cttccaaaag ctggcggatg ttttcgtctt ggtcatcggg
     7861 ttcatcctga agtttttcat catattggcc ggaatcatct tattaccacc gctagtatta
     7921 gtcgtattca ttctggtagt cgtaacattt gcgttgctca tgggtggggc cggattcatc
     7981 tataacctct ctccgttcgg agcggacttg ataaacggag caccattgtc aatggcaatc
     8041 atgggatgca tagggacaat cttattcatc ggtatcccca tattctcctt gatatacgct
     8101 atttgcagcc aattattcaa ggtacgcccc ttaccgacgc aagcaagatg gatattatta
     8161 gccttatggc ttatctcctt tatattatgt ggcgtatata tccatcaatc cggtatgcta
     8221 tatgactggc ataattattg gaacggtgta cacgattgga acaggcatgc cgtttggctc
     8281 ccttaacctt atccgaaggc gtaaaatgaa gatatagatt tagtagttta taatgtttat
     8341 tgtgtgttta aaaaaagaag gccgctctgt cacagagggg cctttcttct aaggttaaca
     8401 aatttatgag taaaaaccac taatgaatca tattaatgat ttgctgtccc ctttgcatga
     8461 tattgtcacg cataaaacag cgggtacaaa tataaccaat tttttataat taaaaaatta
     8521 tattcaatta tttgaattct tttctaatct tagcggcgat ctcggccaat tcttcttgac
     8581 ttacagccaa tttcttcccg ccgaaataca tatcggactc cttcgtgata ggaatcaaat
     8641 ggatatgcgc atggggcact tccaagccca tgacagccaa ccctacacgc ttacactcga
     8701 tagcggtctc ttgggcacga gctacccgtt tagcgaaagc taccatccgt cccagcatcg
     8761 gatcatcgat atcaaagata taatcgacct ccttcttggg aattaccaag gtatgcccca
     8821 aggctaccgg attgatatcg aggaaagcaa aaaactcatc gtcttccgca accttgtggc
     8881 tagggatctc acccgccacg attctactga aaatagttgc catacgtctt tctgttttta
     8941 aattgaaata tccataatct caaacgtcat caagccggaa ggtacacgga tctcaacgac
     9001 atcccctacc ttctttccca tcaaaccttg ggcgatcggc gtgcttacgg agatctttcc
     9061 ttcttttagg ttagcctccg aatccgatac caacgtgtag gtcatgacag cgttattctt
     9121 cgtattctta attttcacct tgttcaaaat ctgaacctca tctgttttca cacgactctc
     9181 atcgatcaga cgggcgtttg agatcaaacc ttttaactgc gcaagcttag cctccatgat
     9241 accttgagcc tctttggcgg catcgtactc agcgttctcg gataagtcac ccttatccct
     9301 cgcctcagcg atctgggctg atatttcagg gcgcttcacg gtctccaaat agttgatttc
     9361 agctaaaatc ttatcgtagc cgtcctttgt catataacta acagccatat taaatcctcc
     9421 ttattcttta tattaatatt gattgattat cgcataataa aaaagaatcc cgaccaagtc
     9481 atatggccgg aactcccctt ttttatcatt tcaagactcc gcaaagttag gttatctttc
     9541 taagatgaac aagtttacga aagtgcttta taacatataa atctgatgat taaaccatga
     9601 acaatttaca atacggactt gatgtcagcc tcaagtttct tcacgtcatc cacccgttta
     9661 accaagtttc ccttgcgatc caagataaag atcgccggaa gctgtttcac gttatacaac
     9721 gccgcggtct gagagtaaac agactgtgga tcacgcacgc aagtccaagg taaattagaa
     9781 gcggcgttct tccagaagtg gacatcatta tccaaagaga tctggtaaat ctccaagccc
     9841 ttatcgtggt acctcgtata taaatcgcca aattccatat tcaaggcagg agaccattcg
     9901 gacatatagg ccgtgaagtt gatcaacacc accttacctg tagcgacaga agacaatttc
     9961 gtattttccc catgtacatc cggcaactcg atatccaaga aactaacctc tttcttctcc
    10021 accttatcca agtccatcgg gcgctggcta cgaatcacct ttatcgattg aagagccaag
    10081 ttatacagat gcttagcacg agggctttcc ggataatagt gatcgaagct ggtggctacg
    10141 gcaccataag ccttcgagtc gttcttgtca tacaaatcga agaacagcaa gccgtcgatt
    10201 tgctggaaca aggcaaagta agcggcagcg gacatcgggg cggaataaat atacttacga
    10261 gccacgtcct tataagcctc ggcggcctcg agcacctgac gggaatatac ggaatccgcc
    10321 aacagaccgg actcagactc tttccgtaaa cgatggatcg cttggttcgc gtctaattga
    10381 gccaaagtaa tattcttgat cgccttgcaa ttctctgagc cctccacgct ataagaagta
    10441 gcgaaagtcc cggcatcggc cacgaacgag atcgtctccg tagaatctac cgagaagttg
    10501 atcaattggt tattcagacg caagcgataa aaatccggga atgccggacg aggcttcgta
    10561 aagctgaatt tacccgccgc cgtcagtttt acggagtcca tcaactctac cgtcgacaca
    10621 cctacattct ccagatacat catctggcca tcagcgccgg acactacacc ttccaccgta
    10681 aaatcagaat tcttcttaca agccgtgaac aaaagcaaca taacacacag cacagctagt
    10741 aaattcgtag atatttgttt cattattcca gtttgtctat attactaatc tggtgcaaat
    10801 atacattatt ttacaattgt ggcactatta ttccgtattt cttcaaggct tttttcaaaa
    10861 aaagtatttc aagactgtta tttcttttca ttttcatgca attacaggta aactttcatt
    10921 acatttgcac caatttttga cagatagaaa aataagaaaa aagattatgc ttaatccaat
    10981 taacaagacg atcgagttag gtgatggaag aaccattacc atcgaaaccg ggaaattggc
    11041 caaacaggcg gacggagcgg ttaccgttcg tatgaacaac accgtgttgc tcgccactgt
    11101 ttgtgccgct aaagatgcga acccgggtgt tgacttcatg ccgttgcaag tagaatacaa
    11161 agagaaatac tccgcttttg gacgtttccc cggaggtttt acaaaaagag aaggaaaagc
    11221 ttctgattat gaaatcctca catctcgttt agtagaccgt gcgttgcgtc ctcttttccc
    11281 ggacaactac cacgctgagg tatatgtaaa tattatattg ttctccgcgg atggcgaaga
    11341 tttgccggac gcattagcag gtttggccgc ttccgccgct ttggctgtct ctgatattcc
    11401 ttttaacgga ccgatctctg aggttcgtgt agctcgtacg gatggaaaat acatcgtcaa
    11461 cccaacttcc gcggaattgg agaaagctga tatcgacatc atggttgccg ctaccataga
    11521 caacatcatg atggttgagg gtgagatgaa cgaggttcag gaatctgaga tgcttgaggc
    11581 tatcaaggtc gctcacgagg ctatcaaggt acaatgcaag gcccaattgg aattatccga
    11641 ggcttgcggc aaattggtaa aacgtgaata ttgccacgag gtaaacgatg acgagttgcg
    11701 caaggacgta cacgacaaat gttacgccaa ggcttacgcc gtagccacat ccggtagcgg
    11761 caagcacgaa cgcagcgagg cattcgagaa aatcgtagaa gaatacaagg ctcaattctc
    11821 cgaggaggag ttgacggacg agaaactgga aatgatcggt cgctactatc acgatgtaga
    11881 gaaagaggct atgcgccgtg ccatccttga tgagggtaag cgtttggatg gtcgtaagac
    11941 taccgagatc cgtccgatct ggatcgagac agattgcctg ccgggtcctc acggttccgc
    12001 tatctttaca cgtggagaga ctcagtcttt atctacggta actttaggta cgaagtctga
    12061 tgagaaaatg atagacgacg tattgaacca tggatacgag cgtttccttt tacattataa
    12121 cttccccccg ttctccacag gcgaggccaa agcaacacgt ggcgtaggcc gtcgtgagat
    12181 cggacacggt aacttggctc accgtgcgct gaaacgtatg atcccggaca actatccgta
    12241 tgtagtacgt gtaatctccg atatcttgga gtctaacggt tcttcttcta tggctacggt
    12301 ctgtgccggt accttggcgt tgagagacgc aggtgtcccg atgaagaaac cggtatccgg
    12361 catcgctatg ggattgatct ctgagaacaa gggtacgaac tacgcgatct tgtctgatat
    12421 cttaggcgac gaggatcact tgggtgatat ggacttcaag gtaacgggta cgaaagacgg
    12481 tatcacggct acccagatgg atatcaaggt agacggtttg tcttacgaga tccttgagaa
    12541 tgctttggct caagcgaaag agggtcgtat gcatatcttg ggcaagatat tggaggctca
    12601 accggaagct cgcgaggatt tgaaacctca tgcacctcgt atcgagacga tgattatcgg
    12661 taaagaattc atcggtgcgg taatcggccc gggcggtaag atcatccaag gtatccaaga
    12721 gaagacggga gctacggtat ctatcgatga ggtagacggc gtaggaaaga tcgagatctc
    12781 cggcacgaat aaggctacga tcgacgcggc tgtcaaggcg atcaaaggta tcgtggctgt
    12841 tcctgagatc ggagaggttt atgaaggaaa gatttcctct atcatgcctt atggtgcgtt
    12901 cgttgagttc atgccgggca aggatggttt gcttcacatt tccgagatcg actggaaacg
    12961 tctggagacc gttgagcaag ccggcttgaa ggaaggcgat acggtttctg tcaagttggt
    13021 tgatatcgat ccgaagacag gcaagttcaa actttcccgc aaggtattgc ttccgaaacc
    13081 ggaaggttac gaggaacgtc caccaagacc agaaagaggt gagcgtggac ctcgtccaga
    13141 ccgtggagac cgtggtcctc gtcaagatcg tggtgatcgc ggacctcgca gggagtacag
    13201 agactaagat aaggtcttat acattatata taatcccggg tagattaaac gctatccggg
    13261 atttttttat caaatcatct accacaccta caactatagc tataagcaat tggtcataag
    13321 ttatttatcg agtggtggta gataaatagc atctaccact attggctcgt atctaccacc
    13381 atttactact tttcaatcac aaaacaccat cgtcccctac tcgccaaccg cattattagt
    13441 cctatctttt tcaagaagcg gcagaagacg gagacattgc ttagccggca agctatctat
    13501 ttgatcatgc ttcatatatc atctaaaaaa ctgattaatt gatatttata gtttttctta
    13561 gtataaaaca aaagttttcc gctatggaaa catttgtttc ctcatgagga aaccttagtt
    13621 ttgtgcttac gaaactttag ttttccctag gagaaactgt ttgctcttgt atgttaatct
    13681 attatcatgt atctctaatc tgaacgcaca agtatttaaa ttagaaaacg gcttagcttt
    13741 ttcgaaatta caaacaaaag gagtcaaagg tgcaaatata gatttatacc cccataagtt
    13801 aacgacttat caaatatcat tagatatcga gtatttacaa acaaaacatt tctatttatc
    13861 aagttccatt ggttaccttg aaaaaggagg caaatataca gacattgtaa atcaatccat
    13921 gagtgagaga catatcaatc agtatataac aatacaaaac aaagaaattc tcaacatcct
    13981 catcactaat ttttatgtta ttactaaaat taccggatag caaacctagt acagactaaa
    14041 caaacgacca taaaccttat atccaggcca tgatcatcgt ttagcctgca caaacagtaa
    14101 cgtttaataa atataagcgt aattccaagc caaagcattc aaactgggat cccatcgatt
    14161 ccactgacgc cccagcatat catatttaac ttgatatgca gccgttttca tatagaatct
    14221 attacctgtt tgaccatcta ccgcacaacc tcgcagtccc ccaccaattg agttcggatc
    14281 aaatccacat tttggagact ctttagttac tcccagggtt ccgtccggaa gggtcaccat
    14341 ttttctaaca atatagatat cacaaaagta ataaccagta ggaatatttg taggtgattt
    14401 gttgataaga acttttttat tttcttccac taagaatgtg ttatcatatc ctgtcacact
    14461 aaaagtctca ctcgtagcct tagtctcaat taatggggat tgttctgatt ccataaattc
    14521 acccataagt tcaataaact gattccacgt aattgcacca ttagcttccg cacatttcct
    14581 caaatcttct tcactcatgt tatcatagtc aagaccatct cctacgataa cctcttcttg
    14641 gttagaacaa gaagacacaa aaaacaaaaa caaacatgat aaaattagaa tctttttcat
    14701 acaaaaaact atttataaat taaacattga ataatcaaag aaattaaata ttacaaatca
    14761 tcctcacatt caattttaga aaagaataaa aaactcttca tagatgttgt ctccttctac
    14821 tcttattaaa taaggtttaa ataaaagacc ttgcatggaa atacaatagc tctgagaagt
    14881 agaaagaggt acagactctt catatacgag catcccacta tcatcaacaa tttgtataaa
    14941 cacattgtct aatggcttca taaaatagaa catgattcca tcatttacaa tcttcacttc
    15001 taccggatta ggagaaatag agcgctcctc ttcctcatca cgctcattct tatgctctct
    15061 tccagccacc gtatgtgtcc ataagcatac acaactcaat aaagtcaaaa ataaaaatct
    15121 tttcatccca ttcatttttt gactgcaaaa gtatccgata aggttggatt cggggctaaa
    15181 acactgttc
//
LOCUS       DBMDTB010000094        15075 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_1240_length_15075_cov_10.993121, whole genome shotgun
            sequence.
ACCESSION   DBMDTB010000094 DBMDTB010000000
VERSION     DBMDTB010000094.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 15075)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 15075)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15075
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1240_length_15075_cov_10.993121"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..1800)
                     /locus_tag="ACZPB4_13385"
     CDS             complement(<1..1800)
                     /locus_tag="ACZPB4_13385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tex family protein"
                     /protein_id="HIR1099242.1"
                     /translation="MTNVFHTLIARFLQIPEGQVERTIGLLNEGATIPFISRYRKEVT
                     GGLDEVQIGAIKDQLDKLTELSKRKETILATIEEQGKLTPELRKRIEESWDSTEIEDL
                     YLPYKPKRVTKAEIARRKGLEPLAKIVMMQNENNLSARIKSFIKGEVKNAEEALQGAR
                     DIIAEWINENESARNTVRNSFAHTAMITSKVIKGKEEEGAKYRDYFDFSEPLNRASSH
                     RLLALRRGEAEGILRVSISPDAESCLDRLNRRFVKGRGEVSEQVATAVDDSFKRLLKP
                     SIETEFSNQSKAKADEEAIRVFAENLRQLLLAPPLGQKRVLGVDPGYRTGCKLVCLDA
                     QGNLLHNEAIFPHPPQNEKGKAAAKVAQLVATYAIDAIAIGNGTASRETEQFITNIRY
                     DRKVQVFVVSENGASIYSASKIAREEFPEYDVTVRGAVSIGRRLMDPLAELVKIDPKS
                     IGVGQYQHDVEQNALKKSLDQTVESCVNLVGVNVNTASKHLLTYISGLGPTLAQNIVN
                     YRAEHGPFTSRKELMKVPRMGEKAFEQSAGFLRIPDGKNPLDNSAVHPESYPIVERMA
                     KDLKCSVADLITDKALKKKLKLTDYLTDKVGMPT"
     gene            1953..3461
                     /locus_tag="ACZPB4_13390"
     CDS             1953..3461
                     /locus_tag="ACZPB4_13390"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1099243.1"
                     /translation="MEVNTTENKTLEQDYRDLAGLLSNIVDSLPIYFFVKDTGDNFRY
                     VYSSPLMNQLYGRYHNDVVGKTDFDLFLDPVVAQSFRDMDEEVVKTGKMQRFVEQMID
                     PKGILRTMDTMKLLAPREDKPPYLVGISWDITKQRQVEEELHSYNKRLALACQAGKIY
                     PWLWDLVNGTAELSLEENGQIKHVQITHASFTEKIHPDYRKVYENITTAFMRGEIDSM
                     RFSFPCRYFSDEYVWLEKIGEVYEADPDGKPIRSIGILRDMTVDKRHEADVQAKRLAE
                     ESDRMKSAFIANMSHEIRTPLNAIVGFSTLLAESDDEEEKKEYLRIIESSNEFLLQLI
                     GDILDISKIESGKMEFIYTTLRLSEIFAPQQQAFALRVVPDVKVIFESDGNDYCIVSE
                     KTRLTQVLTNFLSNAVKFTSSGSIRFGYRLTDDGIYVYVTDTGMGISKESQASIFNRF
                     VKLNSFKQGTGLGLSICKTIIEKLKGKIGVESEEGKGSTFWFTIPCQPMKVK"
     gene            complement(3484..4842)
                     /locus_tag="ACZPB4_13395"
     CDS             complement(3484..4842)
                     /locus_tag="ACZPB4_13395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HIR1099244.1"
                     /translation="MRLRKTITTIVATAILLAGWQLFAVIANQPELIPSLPRLVRTLC
                     EWLVSGSFYQSVGATILRGILGMSISFVCAIGMAGLFARFEWVYELFRPLLAIMRSIP
                     VISFILLALIFLNPESIPLMIAFLTMFPLLTENLTRGILDLRPGLSIMARQFHIRRSN
                     VLFQIIYPQLKPFLYSGLASATGFGWRAIIMGEVLSQCAFGIGSEMKRAQNFIAVPEL
                     LAWTIVAVFISFFFDKGISKVADITPKISFANEDQTIPTPTLSVLDTKDISYQYGIQH
                     FSHSFQKGIIYGISAPSGKGKTTLLNLIGGILLPTEGEIHPTRHFGIATIFQQPQLLP
                     HLTAEENIILPLSSFLTEEKARRIAQKHLQEMEMEPFGNRYPKELSYGQQQRIAIARA
                     LAYPSPLLLMDEPFKGLDEALSHRIIERIREMQMKEERIILFTSHNPDEIRLLADEVI
                     YL"
     gene            complement(4839..5747)
                     /locus_tag="ACZPB4_13400"
     CDS             complement(4839..5747)
                     /locus_tag="ACZPB4_13400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008771912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HIR1099245.1"
                     /translation="MIKYIFLLLILCCSGCRHAQTEDTVIKVSVLRGPSVIAFADWLE
                     NPPIIDNKKVQVKVVDSPDLAQALLIKQETDIAVLPMINAANLYNKGIKIKLAGCPIW
                     GTLYLVEKTPLKEPALYVFGNGTTPDILTRYYLGRQRLDYPLNYAFNTAGEITQGILA
                     GKVNRAVLGEPFLSIALRKDSSLRITADLNHFTDNDTLGFAQTAVVYTPTMEKYRIAF
                     EDALRASCQKAVRYPKETIHSLEEHGIFAQGALTPKSIERCKIHYLSAIEAKDAVMGF
                     LRLIEQYEPKAVGGRLPDAGFIHEKQ"
     gene            complement(5918..7471)
                     /locus_tag="ACZPB4_13405"
     CDS             complement(5918..7471)
                     /locus_tag="ACZPB4_13405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008771913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HIR1099246.1"
                     /translation="MSTLTLGIIVIIYMFVIAWLGYLGYRQTKNASDYLLGGRKVNPI
                     IMALSYGATFISASAIVGFGGVAATFGMGIQWLCLLNMFMGVVVAFIFFGRRTRKLGE
                     AHNARTFPQLLGLHYKSRSIQIFIASIIFIGMPLYAAVVMKGGAVFIEQMFHIDLHLA
                     LLIFTLIVAAYVITGGIKGVLYTDALQAVIMFACMLFLLFWFYHIMDMGFIEANQKLT
                     DIAPMVPERFKALGHQGWTAMPISGSPQWYTLVTSLILGVGIGCLAQPQLVVRFMMVE
                     STKQLNRGVLIGCVFLIVTVGAIYHVGALSNLFFLKTEGVVASEAVKDMDKIIPLFIN
                     KAMPEWFGAVFMLCILSASMSTLSAQFHTMGAAFGADAFPKLGRSKNPNSTLGVRIGV
                     LCSILVSYVICYTLSASIIARGTALFMGICAATFLPTYFCSLYWKGATRQGALASLWV
                     GGLASLFAMLFLHKAEAAPVGLCKALFGQDVLIDVYPWHAIDPILFALPLSAITIVLV
                     SLATQKKAF"
     gene            complement(7468..7611)
                     /locus_tag="ACZPB4_13410"
     CDS             complement(7468..7611)
                     /locus_tag="ACZPB4_13410"
                     /inference="COORDINATES: protein motif:HMM:NF045580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="symporter small accessory protein"
                     /protein_id="HIR1099247.1"
                     /translation="MFGISDPGIWLAYLLAFACFLFSIWFGITTWNKEDDEKTNPTKG
                     SRK"
     gene            complement(7625..8050)
                     /locus_tag="ACZPB4_13415"
     CDS             complement(7625..8050)
                     /locus_tag="ACZPB4_13415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005638024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase"
                     /protein_id="HIR1099248.1"
                     /translation="MTVNQISIFLENKYGKLSEILALLAEERIRIIAATVADTSEYGI
                     LRIIVSDPQKAYKILKENNVSANLTDVLAIVTSSCAGSFANTLSYFTKAGISIEYMYC
                     FSIREKAILILRTNNRESAREVIRRQNLEYICESDLIKL"
     gene            complement(8074..9375)
                     /locus_tag="ACZPB4_13420"
     CDS             complement(8074..9375)
                     /locus_tag="ACZPB4_13420"
                     /EC_number="6.2.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047475 - phenylacetate-CoA ligase
                     activity [Evidence IEA];
                     GO_process: GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetate--CoA ligase family protein"
                     /protein_id="HIR1099249.1"
                     /translation="MMYWQKEIETMDRKDLVKFQLERLKQTIELAGNSPFYHKIFKEK
                     GITPDSFQSLEDLQKLPFTTKDDLRNNYPFGLAAIPLQKCVRIHSSSGTTGNPTVVLH
                     SAKDLDQWANQVARCMYMVGLRDTDVFQNTSGYGMFTGGLGFQYGAEKLGALTVPAAA
                     GNTKRQIKFITDFGTTCLHIIPSYATRLAEVMYEEGIDPRKDTKLHTVCIGAEPHSEE
                     QRKRIEQLLGVKAYNCFGMSEMNGPGVAFECTEQNGLHIWEDNVIVEIVDPVTLQPVP
                     EGEVGELVLTTINREAMPLLRYRTRDLTCILPGDCPCGRTHKRLARFKGRSDDMIILK
                     GVNLFPIQIEKILMQFKELGSNYLITLETIGNSDEMLIEVELSDLFTDDYSALQRLTK
                     GITRQLKDELLLTPRIKLVAKGSLPTTDGKAVRVKDHRKLC"
     gene            9574..10845
                     /locus_tag="ACZPB4_13425"
     CDS             9574..10845
                     /locus_tag="ACZPB4_13425"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing sensor histidine kinase"
                     /protein_id="HIR1099250.1"
                     /translation="MGKYDHLSKEELIQRIERLEADLEKATLTPSASDNELEMRQSQH
                     TINFLNILMDTILSNVFVEITVKDIFNGFRYIYFNKAAEEFTGVKAEDILGKTDFELF
                     PDSRRAHEIRTEDYHTIKTGRMVKEMVEYEKPNGEVRIVNIVRLLITNPDPGASPLLL
                     VMLNDITEQRQDQLALMKVQEADKMKNAFIANMSHEIRTPLNAIVGFAHLVTETTNAS
                     EQREYFSIINKNCDLLLKQINDILDLSKIESGRLNYNVSEVELRDICQEAYVVQSLKM
                     TSDVALLYNSVAMPSVRLWIDPHRVEQVLLNLLSNAIKFTSKGFISLFYEVEDMFVRV
                     SVMDTGIGISEEKLESVFERFVKLDDFYQGAGLGLPICKMIVEQLGGEIGVRSELGKG
                     STFWFTLPLVVTDKAVVEKDDPSVLSECQLY"
     gene            10857..11429
                     /locus_tag="ACZPB4_13430"
     CDS             10857..11429
                     /locus_tag="ACZPB4_13430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1 family glyoxalase III"
                     /protein_id="HIR1099251.1"
                     /translation="MKNAVVFLATGFEEIEALGTIDVLRRGGVRVMMVSITGDRLVIG
                     AHDIPVMADYLFEEADFGCVDALILPGGIPGSNHLNAHAHLKELVKEKTEEGVLIGAI
                     CAGPMVLGGLGLLKGKRATCFPFFEPTMVGATPTDNGVEQDGNIITSKGPGFMFEFGL
                     TILRNLKDEEIALEVADALLYDALLHGTKH"
     gene            complement(11518..12027)
                     /locus_tag="ACZPB4_13435"
     CDS             complement(11518..12027)
                     /locus_tag="ACZPB4_13435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008199 - ferric iron binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin-like domain-containing protein"
                     /protein_id="HIR1099252.1"
                     /translation="MAKESVKILRGKLDVDNLLSQLNAALAEEWLAYYQYWVGALVVE
                     GAMRSDVQGEFEEHAEEERHHAQLLADRIIELEGVPVLDPKQWFELARCKYDSPTDFD
                     VVSLLNQNVASERCAILRYQEIAKFTDGIDFTTCDIAKHILAEEEEHEQDLQDYLTDI
                     ARMKKSFQK"
     gene            complement(12136..13458)
                     /locus_tag="ACZPB4_13440"
     CDS             complement(12136..13458)
                     /locus_tag="ACZPB4_13440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family protein"
                     /protein_id="HIR1099253.1"
                     /translation="MNRRTFMQKTGLIMSGLTLSPLIGKSYSSIYGQTAPSNKVKVAL
                     IGCRSMGYGDLNTFLDYPETECVALCDVDDEWLNKRAADVEKKTGKKVPHLYKDWRRV
                     IDNKDVDVVIIGTPDHWHCLPTVWACQAGKDVYVEKPLSNTIEECNLMEKAARKYNRI
                     VQVGQWQRSDPHWDEAANFLKAGNIGRIRTVKVWAYQDGKPTLPVKPDCDAPAGVDYD
                     MWLGPAPKRPFNPYRFHYNFRFFWDYAGGLMSDWGVHLLDYALEGMNAGLPTRVFSGG
                     GKFAYPDDAMETPDTLMATYAYKDFNIIWDHACGINHGLYNRKEGLAFYGENGTMVLD
                     RAGWEVIPVVSNNVARMEAVPFKKGEGKGLYNHVGNMLSCIKSRELPNADVAIGARVA
                     KMAHLANISCRVQREVHWDDKNNLFVGDNEATALSKAYYRAPWELPKL"
     gene            complement(13463..14953)
                     /locus_tag="ACZPB4_13445"
     CDS             complement(13463..14953)
                     /locus_tag="ACZPB4_13445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cobyric acid synthase"
                     /protein_id="HIR1099254.1"
                     /translation="MKQHLRPIMFVGTCSDAGKSVINAAFCRIFKQDGYQPAPFKAQN
                     MSLNSYSTPEGGEMGRAQVVQAEACGISPHTDMNPILLKPTNDKSSQVVLNGKPVGNM
                     SAKDYFGIQNQKEELFKEAIEAFKRLEARYNPIVLEGAGSISELNLRDRDITNMRMAI
                     AAGASTYLVADIDRGGVFGSVYGTIALLRPEERVLMKGVIINKFRGDASLFEEGRNLL
                     KELTGIPVVGVIPWFRDIKIEEEDSVALDMKNNTYKDGKINVAIILLKRMSNFTDFDV
                     LEMDPRFNPYYTNNIDEIEKADIILLPGSKNTLSDLQSLRANGIAMAIIRAHKAGKKV
                     IGICGGYQMMGVRLEDPESIEGNIPAIPGLGLLPQCTVIEQEKITRQSDFAFLPSSEN
                     KDCKGYEIHMGRTTLLGDAPEQPVARLEDGRTDGYYLNNRCWGSYMHGILDNPAVLDN
                     LAEGFDTETTTGPFEYAAFKEEQYDKLAALVREHVDMEYIYNSIKN"
BASE COUNT         3777 a         3408 c         3645 g         4245 t
ORIGIN      
        1 ggtaggcatc ccgaccttat ccgtaaggta gtccgttagt tttagtttct ttttaagcgc
       61 tttgtcggtg atcaggtcgg ctaccgagca ttttaggtcc ttggccatcc gttcgacgat
      121 cgggtagctc tcggggtgta cggccgagtt atccaacggg ttctttccgt cgggtatccg
      181 taggaatccg gcgctttgct cgaaagcctt ctctcccata cgggggactt tcatcagttc
      241 tttccgggaa gtgaaaggtc cgtgctccgc ccggtaattc acgatgtttt gcgctaacgt
      301 agggcctaat cccgagatgt aagtcagcaa atgcttgctc gccgtattca cgtttacacc
      361 caccagattc acgcaactct ccacggtttg atccagactc tttttcaagg cgttttgctc
      421 tacgtcgtgc tggtattggc cgacaccgat actcttcggg tcgatcttga ccaactcggc
      481 caaagggtcc atcagccggc gaccgatgct gacagctccg cgtaccgtga cgtcgtattc
      541 gggaaactcc tccctagcga tcttggacgc ggagtagata gaggctccgt tttcgctgac
      601 tacgaacact tgtaccttgc ggtcgtatcg tatattcgtg atgaactgct cggtctcacg
      661 gctggccgta ccattaccga tggcaatggc atctatggcg taagtggcta ctaactgggc
      721 gaccttagcg gcggctttgc ccttctcgtt ctggggcgga tgcgggaaga tcgcctcgtt
      781 atgcagtaaa ttcccctgcg catccagaca gaccaactta catccggtac ggtatccggg
      841 gtctacgcct aatacccgtt tttgtcccaa gggaggagcg agcagcaatt gccggaggtt
      901 ctcggcaaat acccggatcg cctcctcatc ggctttcgcc ttgctctggt tggagaactc
      961 cgtctcgata gagggtttca gcaggcgttt gaaagaatcg tcgacagctg tagccacttg
     1021 ctcggaaacc tctccacgac cttttacgaa acgccggttt aagcgatcca gacaagattc
     1081 cgcgtcggga gagatactta cacgaaggat accttccgcc tctccccgtc ggagagccaa
     1141 taagcgatgg gaactggccc ggttcaaagg ctcgctgaaa tcaaagtaat cccggtattt
     1201 agcgccttcc tcttctttcc ccttgatcac tttggatgtg atcatggcgg tatgagcgaa
     1261 agagttacgt acggtattac gtgccgattc gttctcgttg atccattcgg cgataatgtc
     1321 ccgtgcccct tgcaaggctt cttcggcgtt tttcacttcc cccttgataa aactcttgat
     1381 gcgtgcggat aggttattct cgttttgcat cataacgatc ttagccaagg gttccagtcc
     1441 tttccggcgt gcgatctccg ccttggtgac ccgtttcggt ttgtaaggga gatataaatc
     1501 ctcgatctcg gtgctatccc aagactcctc gatgcgtttc cggagctcgg gagtaagttt
     1561 cccttgctct tctatcgtgg cgaggatcgt ttcctttcgt ttgctcagtt ccgtcagttt
     1621 atccagttga tctttgatgg caccgatttg cacctcgtct aatcctccgg tcacctcttt
     1681 ccggtaacga cttataaaag gtatggtagc gccttcgttc aagagcccga ttgtccgttc
     1741 cacttgtcct tccggaattt gtagaaaacg ggctataagc gtgtgaaata cgtttgtcat
     1801 atctagtttt cttagaattg gagtacaaat atacggtttt gcttatattt tcggtcggga
     1861 tgctcacttc ttgggcttat tatttgtatc tttcattaat tttcaagaat tttacggccg
     1921 gaatattcaa gcctttgatt aaaaaaatca acatggaagt taatactacg gagaacaaaa
     1981 ctttggaaca ggattatagg gatttagcag gattgttatc taatatcgtg gactcgttgc
     2041 ccatctactt tttcgtgaag gatacgggtg ataatttcag gtacgtgtac tccagccctt
     2101 tgatgaacca actttacgga cgatatcata atgatgtggt cgggaaaaca gattttgacc
     2161 tatttctaga tccggtcgtc gcccaatctt tcagagatat ggacgaggag gtggtgaaaa
     2221 cgggtaagat gcagcgtttc gtggagcaaa tgatcgatcc gaaaggtatc ttgcgtacta
     2281 tggatacgat gaaactgcta gcgccccgtg aggataagcc tccttattta gtagggattt
     2341 catgggatat tacaaagcaa aggcaggtcg aggaggagtt gcatagctat aataagcgct
     2401 tggcgctcgc atgtcaagcg ggtaagatct acccgtggct ttgggatctg gtaaacggta
     2461 cggcggagct ttccttggaa gaaaacggcc agatcaagca tgtgcagatc acccacgcta
     2521 gttttacgga gaagatccat ccggattacc ggaaagtcta tgagaatatt acaaccgctt
     2581 tcatgcgggg cgagatcgat tccatgcgat tcagtttccc ttgtcgttat ttctcggatg
     2641 agtatgtatg gctggagaag atcggtgagg tctatgaggc tgatccggat ggcaagccga
     2701 tccgctcgat cggaatcctt cgggatatga ccgtcgataa acggcacgag gcggatgtgc
     2761 aggctaagcg tttggcggaa gagagcgacc ggatgaagtc cgcttttatc gctaacatga
     2821 gccatgagat acgtacccct ttaaatgcca tcgtcggctt ttccacctta ttggcggaga
     2881 gtgacgatga ggaggaaaaa aaggaatatc tgaggatcat agagagtagc aatgagtttt
     2941 tgttgcagtt gatcggtgat atcttggata tctcgaagat cgagtcagga aagatggagt
     3001 ttatttatac gaccctgcgt ttgagtgaga tattcgctcc ccagcagcaa gctttcgcct
     3061 tgagagtggt cccggatgta aaggttatct ttgagtcgga cggtaatgac tattgtattg
     3121 tgtcggagaa gacccgtttg actcaggtct tgaccaattt cctttccaac gccgtgaagt
     3181 tcaccagctc gggttctata cggtttggtt atcgtttgac cgatgatggt atctatgtct
     3241 acgtaacgga tacgggtatg ggaatcagta aggagtctca agcgagcata ttcaatcgtt
     3301 tcgtgaaatt gaacagcttt aagcaaggaa caggattagg gctttctatc tgcaagacga
     3361 taattgagaa gttgaaaggt aaaatcgggg ttgagtcgga ggaaggaaag ggctctacat
     3421 tctggtttac gataccttgc caaccgatga aagtgaaata agacattcaa gtttggttgg
     3481 aatttatagg taaatcacct catccgccaa caaccgaatc tcatccggat tatgtgacgt
     3541 gaaaagaatg atccgttctt ctttcatttg catttctcgt attcgttcta tgatgcgatg
     3601 gcttagggct tcatccaagc ctttgaacgg ctcgtccatc aaaaggagag gagaagggta
     3661 tgccaatgcc ctcgctatag cgatacgttg ttgctgtccg taactaagct ctttaggata
     3721 tcggttcccg aagggctcca tttccatttc ctgtaagtgt ttttgggcaa ttcgccgggc
     3781 tttttcctcc gtgagaaaag aggagagggg gaggatgata ttttcttctg cggttagatg
     3841 gggcaggagt tgcggttgtt ggaatatggt ggcgattcca aagtgtcttg tgggatgtat
     3901 ctctccttcc gtaggcaata agatacctcc gattaggttt aataacgttg tttttccttt
     3961 gcctgaaggt gcgctaattc cataaataat ccctttttga aaggaatggg aaaagtgctg
     4021 tatgccgtat tggtaactta tatctttcgt gtctaaaact gataatgtag gggtcgggat
     4081 ggtctgatcc tcattcgcga aagatatttt aggggtgata tcagcgactt tgctaattcc
     4141 tttgtcaaaa aagaaactga tgaataccgc cacgattgtc caagcgagta gctcagggac
     4201 agcgataaag ttttgcgccc ttttcatctc gcttccgatt ccgaatgcgc attgcgacaa
     4261 gacttctccc ataatgatcg cacgccagcc gaatccggtg gcggaggcaa gcccgctata
     4321 taagaatggc tttagctgcg gatagatgat ctggaataag acattggaac gtctgatatg
     4381 gaattgacgt gccataatgg ataaacccgg acgcaggtcg aggattcccc gtgtcagatt
     4441 ctctgttagt agcgggaaca tggtgaggaa ggcgatcatc aaagggatac tttccggatt
     4501 taggaatata agcgccaaaa gtatgaagga tatgaccggg atcgagcgca tgatggcaag
     4561 cagaggtctg aataattcat acacccactc aaaacgggcg aataacccgg ccatccctat
     4621 cgcacaaacg aatgagatcg acatgcctaa gattccccgg agtatagtcg ctccgaccga
     4681 ctgatagaaa ctaccggaga cgagccattc gcaaagtgtc cgtacgagtc gaggaagtga
     4741 aggtatcagc tccggttggt tggctataac ggcgaatagt tgccatcccg ccaagaggat
     4801 agcggtagcg actatcgtag tgattgtttt tcgcaatctc attgtttttc gtggataaat
     4861 ccggcatcgg gaagcctccc gccgacggcc ttgggttcat actgttcgat gagacgtagg
     4921 aaacccatga cggcgtcttt cgcctcgata gctgataaat aatggatttt acaccgctcg
     4981 atactcttag gagttaaggc cccttgggcg aagattccat gttcttccaa agaatggatg
     5041 gtctctttcg gatatcgtac ggctttttgg caggaggctc gtaaggcatc ctcaaaagcg
     5101 atacgatatt tctccatcgt cggggtgtat acgaccgctg tttgggcgaa tccgagggta
     5161 tcgttgtctg taaaatgatt caagtccgca gttattcgta agctgctgtc tttccgtaaa
     5221 gcgatgctta gaaacggttc cccgagcacg gcacgattta cttttccggc taagatgcct
     5281 tgggtgattt ccccggcggt attgaaggcg taattcaaag gataatctaa tcgttggcgg
     5341 ccgagatagt accgggtaag gatatcggga gtcgtaccgt tgccgaatac atacaatgcc
     5401 ggttctttca agggagtttt ctcaacgagg taaagggttc cccagatcgg gcaccccgct
     5461 agtttgatct tgatcccttt attgtacaag ttcgccgcat tgatcatggg gagtacggct
     5521 atgtcggtct cctgcttgat cagtaaggct tgcgccagat cgggcgagtc taccacttta
     5581 acttgtactt tcttgttatc tataattgga ggattctcaa gccaatcggc gaatgcgata
     5641 acggatggac cacgaagtac cgaaaccttg attacggtat cttccgtttg tgcgtgccgg
     5701 caaccggagc aacaaagtat caatagtaga aaaatgtatt taatcatatc tagacctcta
     5761 taaaacaatt aaggattgcc tcccggcaac ccctaaccaa ctttgttaac cttaaatcta
     5821 atactattat gaaaaaacca cagtgcaaat gtactgtttt ctatatatct gtcaatagaa
     5881 taaatgctaa ttagtgtttt gaggttcata agaaaagcta aaaagccttc ttttgagtcg
     5941 ctaggctaac caaaacaatc gttatcgccg ataatggcaa agcaaataag atcggatcta
     6001 tcgcatgcca cggatataca tcgatcaaga cgtcttgtcc gaataaagcc ttgcaaagtc
     6061 ctaccggagc cgcttccgcc ttatgaagga acaacatggc gaataaactg gccaagcctc
     6121 ctacccataa gctggccaag gccccttgcc gggtagcccc tttccaatat agcgagcaga
     6181 aataggtagg taggaatgta gccgcgcaaa tacccatgaa caaggcggtg cctcgtgcga
     6241 taatactcgc gcttagcgta tagcagataa cgtagctgac caagatagag catagcacgc
     6301 cgatacgtac acctaatgta gagttcggat ttttgctacg tcctagtttg gggaatgcgt
     6361 ctgccccgaa agccgctccc atggtatgaa attgtgcgct aagggtagac atactggcag
     6421 agagaataca aagcatgaaa accgccccga accactccgg catcgcttta ttgataaata
     6481 gggggatgat cttgtccata tcttttaccg cctcggaggc gactacacct tccgtcttga
     6541 ggaaaaacaa attagacaag gctcccacgt gataaatcgc ccctaccgtg acaatcaaga
     6601 atacgcagcc gatcaatacg cccctgttga gttgcttggt actttccacc atcatgaagc
     6661 gtacgactag ttgtggctgc gctaagcaac cgattcctac gccaaggatc aatgaggtaa
     6721 ccaatgtata ccattgtgga gagcctgaga tgggcatagc tgtccatcct tgatgtccca
     6781 aggccttgaa gcgttcgggc accatggggg cgatatccgt caacttctgg tttgcctcga
     6841 taaagcccat gtccatgata tggtaaaacc aaaatagcag gaatagcata caagcgaaca
     6901 tgataaccgc ttgcaacgca tccgtataaa gtactccctt gattccgccc gtaatcacgt
     6961 aggccgctac gatcaaggtg aagatcaaca aggccagatg aaggtcgata tgaaacatct
     7021 gctcaatgaa gacggctcct cccttcatca ccacggcggc gtagaggggc atgccgatga
     7081 aaatgatcga ggcgatgaag atctgtatag accgggactt atagtgtaat cccaataatt
     7141 gcgggaaagt ccgtgcgtta tgtgcctcgc ctaacttccg ggtccttcgt ccgaaaaaga
     7201 taaaggctac cactacgccc atgaacatgt tcaataagca aagccattga atacccatgc
     7261 cgaacgtagc ggctacgcca ccgaaaccaa cgatcgccga tgccgagata aaggtcgccc
     7321 cgtaagacag agccatgata atggggttta cttttcgtcc gcctaataaa taatcactgg
     7381 cgtttttcgt ctgcctgtat ccgagatacc ctaaccaagc gattacaaac atgtaaatga
     7441 tgacaataat gcctaatgtt agcgtactca ttttcgtgat cctttagtag ggtttgtttt
     7501 ttcgtcgtct tctttattcc aagtggttat cccgaaccaa atagaaaata ggaagcaggc
     7561 gaacgctaga aggtaagcca gccaaatacc ggggtcgctg attccgaaca tatatccgtg
     7621 cctattaaag ttttattaga tcactttcac agatatactc gagattctga cggcggatta
     7681 cctcacgggc gctttcccgg ttgttcgtac gcaagatcaa gatcgctttt tcccggatgg
     7741 agaaacaata catatattct atgctgatgc ccgctttcgt gaaataagat aatgtattgg
     7801 caaaacttcc ggcgcatgag ctggttacga tcgctaatac gtcggtcagg tttgcgctga
     7861 cgttgttttc ttttaatatc ttgtatgcct tctggggatc gcttacgatg atacgaagga
     7921 ttccatactc ggaggtgtcg gctacggtgg ctgcgatgat gcggatgcgc tcttccgcca
     7981 ataacgctaa tatctcgctt aatttcccgt acttgttttc taggaaaata gaaatttgat
     8041 tgactgtcat aaggtgttat tttaattgtt tatttaacaa agcttgcgat gatctttcac
     8101 tcgtaccgcc ttgccatctg tggttggcaa agatcccttg gctaccagct tgatacgtgg
     8161 tgtaagtaat aattcgtcct tcaactgacg ggtgatacct ttcgtcaaac gctgtaaggc
     8221 tgaataatca tcggtgaata ggtcgctcaa ctcaacctcg atcaacatct cgtcgctgtt
     8281 accgatcgtt tcgagggtga tcaagtaatt actgcctaac tccttgaatt gcatcaatat
     8341 cttttcgatt tggatgggga acaggttcac gcccttcaag attatcatat cgtcgctacg
     8401 tcctttgaaa cgggcaaggc gtttatgggt acgtccgcaa gggcaatcgc ccggtaagat
     8461 gcaagtaagg tcacgggtac gataacggag taaaggcatc gcctcccggt tgatggtcgt
     8521 taataccaat tctccgactt ctccctcggg caccggttgc agggtaaccg ggtctacgat
     8581 ctctacgatc acgttgtctt cccagatatg caagccgttc tgctccgtac attcgaaggc
     8641 tacacccggc ccgttcatct ccgacatacc gaaacagttg taagccttga cacccagaag
     8701 ctgttcgatg cgtttacgtt gttcttccga gtgaggctcg gcaccgatac atacggtgtg
     8761 tagtttggta tcctttctgg ggtctattcc ctcctcatac ataacctcgg ccaaacgagt
     8821 ggcatagctc ggtatgatat gtaaacaggt ggtgccgaaa tcggtgatga acttaatctg
     8881 tcgtttggta ttaccggccg ccgcaggcac tgtcaacgca cctagttttt ctgctccata
     8941 ctggaaaccg aggccaccgg taaacatgcc gtagccggat gtattttgga atacgtccgt
     9001 atcccttagc cccaccatat acatgcaacg agctacttgg ttagcccatt ggtccaaatc
     9061 cttggcggaa tgtaagacaa cggtaggatt acctgtcgtt ccactggaag agtggatacg
     9121 tacacatttc tgtaacggga tggctgccaa tccgaacgga tagttatttc taagatcatc
     9181 tttcgttgta aacggaagtt tttgtaaatc ctccaaggac tgaaaactgt ccggggtaat
     9241 tcctttctct ttgaatatct tatggtaaaa aggggagttg cccgctagtt ctatggtttg
     9301 tttcagtcgt tccagttgga attttaccag atctttacga tccatggttt ctatttcttt
     9361 ctgccaatac atcatcgttt tttcaattag agtgtgttta attcatgaaa ttagattgca
     9421 aatgtatctt ttattttgga taatgccatg cttttgtgtc aaaatattag taatgacctt
     9481 ttgaaaataa gaattattag gcggtaagcc gttgtaaata aaaaaataat agctattttt
     9541 gtccattacg caatttaact ttatgtatgg gccatgggaa aatatgacca cctttccaaa
     9601 gaagagttga ttcaaaggat tgagagactg gaagccgatc tggaaaaagc cactttgaca
     9661 ccatccgcga gcgataacga acttgagatg cgccaaagcc agcatacgat caacttctta
     9721 aatatcttga tggatacgat cttgtcgaac gtatttgtgg agatcacggt gaaagatatt
     9781 ttcaacggtt tccggtatat ctattttaat aaggcggcgg aggaatttac gggggtcaag
     9841 gcggaagata tcttagggaa gacggatttc gagcttttcc ctgattcccg gcgggcgcat
     9901 gagatccgaa cggaagatta ccatacgatc aagacgggac gtatggtaaa ggaaatggtc
     9961 gagtatgaga aaccgaatgg agaggtgaga atcgtaaata tcgtacgttt actgatcacg
    10021 aatccggacc cgggagcctc gcctctgtta ttggtcatgc tgaatgatat cacggagcaa
    10081 cgtcaagacc agttggcgct gatgaaagta caagaggcgg ataagatgaa aaacgctttt
    10141 atcgctaata tgagccatga gatccggacc ccgctgaatg ctatcgttgg ctttgcccat
    10201 ctcgtgacgg aaacgactaa tgccagtgag caaagggaat acttctcgat tataaataag
    10261 aattgcgatt tattgttgaa acagattaac gatatcctgg atttgtcgaa gatcgagtcc
    10321 ggtcggttaa actataacgt gtcggaagtt gagttgaggg atatttgcca agaggcctat
    10381 gtggtacaat ccttgaagat gacttccgat gtggcattat tatataactc ggtcgccatg
    10441 ccttctgttc gtctgtggat cgatccgcac cgggtagaac aggtcttgtt aaatctcttg
    10501 tctaatgcca ttaagtttac ttccaaaggt tttatctcgc ttttttatga ggtggaagat
    10561 atgttcgtac gtgtctctgt catggatacc ggaatcggga tatcagagga aaagctggag
    10621 tctgttttcg agcgtttcgt gaaattggat gatttttatc aaggggctgg tttgggacta
    10681 ccgatctgta agatgattgt agagcagttg ggtggcgaga tcggtgtgcg atctgagctt
    10741 ggcaaaggtt ccactttctg gttcacctta ccattggttg ttacggataa ggctgttgtg
    10801 gagaaggatg atccttctgt tttaagtgaa tgtcaactat attaaataaa aaagaaatga
    10861 aaaatgcggt tgtcttttta gcgacaggct ttgaggaaat agaggccttg ggtacgattg
    10921 atgtcttgag gcgtggtggt gtacgggtta tgatggtatc tattacgggt gaccgattgg
    10981 tgataggagc tcatgatatt ccggtaatgg ctgattacct gttcgaggag gcggatttcg
    11041 gttgtgtcga tgccttgatt ttgccgggtg gaatacccgg aagcaaccat ttaaatgcgc
    11101 atgcccattt gaaagaatta gtcaaggaga aaacggagga aggcgtatta atcggtgcta
    11161 tctgtgctgg accgatggtt ttaggtggtc ttggattgct aaaagggaaa agggctacct
    11221 gttttccttt cttcgagcca acaatggtag gcgctacccc tacggataat ggagtagagc
    11281 aggatggaaa tatcatcaca agcaaggggc cgggttttat gtttgagttc ggcttgacga
    11341 tcttgaggaa tctgaaagat gaggaaatcg ctttggaagt ggcggatgcc ttattatatg
    11401 acgctttgtt gcatgggaca aagcattaat gtgcttgaaa ttaaaatccc ttgagagaat
    11461 gtctctaaga cattctctca agggattttt gttgtaaaga gttttccctt tcctaaatta
    11521 tttctggaaa gattttttca tgcgtgcgat atctgtcaaa tagtcttgca gatcttgctc
    11581 gtgttcttct tcctcagcta agatatgctt agcgatatca caagtcgtga agtcgatgcc
    11641 gtccgtgaat ttagcgattt cttgataacg taagatggcg caacgctcgg aagctacatt
    11701 ctggttcaga aggcttacta cgtcaaagtc tgtcggtgaa tcatatttgc atcgggctaa
    11761 ttcaaaccat tgtttcggat caagtaccgg aactccttcc aattcgatga tccggtctgc
    11821 caataattgg gcgtgatgcc tttcttcctc ggcatgttcc tcgaattcac cttgtacgtc
    11881 ggaacgcatg gctccttcaa cgaccaaggc tcctacccaa tattgatagt atgctagcca
    11941 ttcttccgct aacgcggcgt ttagttgaga taataaattg tcgacatcca atttccctct
    12001 taaaattttg acgctttctt ttgccatagc tgtattaatt tagaattaaa cgtattgttc
    12061 gttttttata gttctaacaa gcttactagg gcattgttta ttgtttgtca aaattttaac
    12121 gttatgctgc gattgttaca atttaggtaa ttcccaaggt gcccggtaat aggctttcga
    12181 caaggcggta gcttcgttat cgccgacaaa caaattgttt ttatcatccc aatgaacttc
    12241 ccgttgaacc cggcaggaga tattcgccag atgagccatc ttcgctacac gggcaccgat
    12301 agcgacatcg gcgttcggaa gctcacggct tttaatgcag ctcaacatgt ttcccacatg
    12361 attataaagt cctttgcctt ctcctttctt gaaaggaacg gcttccatgc gggctacgtt
    12421 attggatacg accggtataa cttcccaacc ggccctgtcg agtaccatcg tgccattctc
    12481 tccatagaac gctaatcctt ccttacggtt atagagtccg tgattgattc cgcaggcgtg
    12541 atcccagatg atattaaaat ctttataggc gtaagttgcc attaaagtat cgggcgtctc
    12601 catagcgtcg tccggatagg caaacttgcc gccgcctgag aatacacggg tgggaagacc
    12661 tgcgttcata ccttctaggg cataatccag caaatgtacg ccccagtccg acatcaagcc
    12721 tccggcatag tcccagaaga aacggaaatt ataatgaaag cgataaggat tgaacggacg
    12781 tttaggagcc gggcctagcc acatatcgta atccacaccg gcgggagcgt cgcaatccgg
    12841 tttaaccgga agtgtcggct tgccgtcttg gtaagcccag accttgaccg tacggatccg
    12901 tccgatattt ccggctttca agaaattagc cgcctcgtcc caatgcgggt cgctacgttg
    12961 ccattggcct acctgtacga tccggttata tttacgggcg gctttttcca tcaggttaca
    13021 ttcctcgatc gtattggaga gcggcttctc tacatatacg tcttttcccg cttggcaagc
    13081 ccagaccgtc ggaaggcaat gccaatggtc cggcgtaccg ataatgacta catctacgtc
    13141 tttattatcg attactcgtc gccagtcctt atataagtga ggtacttttt tccctgtttt
    13201 cttctcaacg tcggcagccc gtttgtttaa ccattcgtca tcgacatcgc aaagagccac
    13261 gcattccgtc tccggataat caagaaaagt attcaaatcc ccgtatccca tgctacggca
    13321 tcctatgagg gctaccttta ctttgttgct aggggcggtt tgtccgtata tggaggaata
    13381 cgatttaccg ataagcggcg ataaagtaag tccggacatg ataagtccgg ttttttgcat
    13441 aaaagtacgt ctgttcatga tattagtttt taatactgtt ataaatatat tccatatcca
    13501 cgtgctccct tacgagggcg gcgagtttgt catactgctc ttccttaaaa gcggcatact
    13561 cgaaaggacc tgtagtcgtt tccgtgtcaa agccttcagc taagttgtcc aatacggccg
    13621 gattatcaag gataccatgc atataacttc cccagcatcg gttgttgagg taatatccgt
    13681 ccgttcgtcc gtcttccagt cgggctacgg gctgttcggg ggcgtcaccc aatagggtgg
    13741 ttcgtcccat atgtatttcg tatcctttac aatccttatt ctccgaggag gggaggaaag
    13801 caaagtcgct ttgtctcgtg atcttctcct gctcgatgac cgtgcattga ggcagaagac
    13861 cgagaccggg aatcgccggg atatttccct cgatactttc cggatcttcc aagcggactc
    13921 ccatcatttg atagccaccg caaataccga tcaccttttt acccgcttta tgcgcccgga
    13981 taatcgccat cgctatccca ttggcccgca ggctttgtaa gtccgataac gtattctttg
    14041 agccggggag caggatgatg tcggctttct ctatctcatc gatattgttg gtataatacg
    14101 gattgaaacg ggggtccatc tccaatacat caaaatccgt gaaattagac attcgtttca
    14161 gcaggatgat agctacattg attttcccgt ctttataagt gttatttttc atatccaacg
    14221 ctacggaatc ctcttcctct atcttgatat cccgaaacca tggaattacg ccgaccacgg
    14281 gaatcccagt caattccttt aataggttcc gtccttcttc gaataaagag gcgtctccac
    14341 ggaacttatt gatgataacc cctttcatta acactcgttc ctccggtcgt aataaagcga
    14401 tcgttccata tacagagccg aatacgcccc cacggtctat atccgcaact aaataggtag
    14461 aggctccggc agcgatcgcc atccgcatat tggtgatatc ccggtctcgc aggtttagtt
    14521 cggagatgct tccggctcct tccaatacga tcgggttata gcgagcttcc agacgcttga
    14581 aggcttcgat ggcttcctta aatagctcct ccttctggtt ttgtatcccg aaataatcct
    14641 tggcggacat attgccgact ggctttccgt ttaatacgac ttgcgagctt ttatcatttg
    14701 tcggctttag taatatcggg ttcatatccg tatgcgggga aataccgcag gcctccgctt
    14761 gtacgacttg cgcccggccc atctcgccgc cttccggggt agagtaggaa ttgagggaca
    14821 tattttgtgc cttgaacggt gccggttgat aaccatcttg cttgaaaata cggcaaaacg
    14881 ccgcgttaat aacgctttta cccgcatcag agcaggttcc gacaaacata atcggtcgta
    14941 ggtgttgctt catctgtata gattttattt acacagtgta caaaggtagt atttttggcc
    15001 tttttattaa ggagaagata tgaaaaaaga agaagatttt gttatgggcc tgtccatcta
    15061 catggcttgt ctgcg
//
LOCUS       DBMDTB010000095        14859 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_1261_length_14859_cov_12.064643, whole genome shotgun
            sequence.
ACCESSION   DBMDTB010000095 DBMDTB010000000
VERSION     DBMDTB010000095.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 14859)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 14859)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14859
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1261_length_14859_cov_12.064643"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            3..113
                     /gene="rrf"
                     /locus_tag="ACZPB4_13450"
     rRNA            3..113
                     /gene="rrf"
                     /locus_tag="ACZPB4_13450"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            369..1526
                     /locus_tag="ACZPB4_13455"
     CDS             369..1526
                     /locus_tag="ACZPB4_13455"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1099255.1"
                     /translation="MSSIYDSRQRWKLGFIFAAVLIAMASVVVSDLLIKDLAREERQK
                     IEVWSEATRVMTSENPSLNMNLILKIIQGNTSIPVILCSETDSVVSYNNIEIPEKNVA
                     QFMTNKVKELRTKNPPIVIDMEDGTYQYLYYDDSIILKRLLVYPYAQLSVVFVFILIA
                     FLALASTKKAEQNKVWVGLSKETAHQLGTPISSLIAWVEYLRTKDIDPSLLTEMDKDV
                     KRLQTIAERFSKIGSDPDPVPTNIVESIRAALGYMETRISSKVKINTYLPERPILVLM
                     NDSLFAWVIENLTKNAVDAMEGQGEISLKVEEREKVVLIDLADTGKGIPKSKFKTVFN
                     PGYTTKKRGWGLGLSLVKRIIESFQGGKIFVKSSELGKGTTFRIKLKKYKG"
     gene            1615..2205
                     /locus_tag="ACZPB4_13460"
     CDS             1615..2205
                     /locus_tag="ACZPB4_13460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceD family protein"
                     /protein_id="HIR1099256.1"
                     /translation="MGKFKLYNVDLKNLSPGVHEFEYLLENKFFVDIDGTEVQKGKVK
                     VHLTVKRSSMMFEMNFQIEGVVVVPCDRCLDDMEIPIDTHNRLVVKFGKEYAEESDEV
                     VVIPEEEGAINLAWFLYEFIALAVPMKHVHAPGKCNKAMSSKLKKHTARSSDETEDDF
                     EDDMGGDDLALEDDGNASPADPRWDALKGLLENDNN"
     gene            2218..2403
                     /gene="rpmF"
                     /locus_tag="ACZPB4_13465"
     CDS             2218..2403
                     /gene="rpmF"
                     /locus_tag="ACZPB4_13465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002562387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HIR1099257.1"
                     /translation="MAHPKRRQGKTRTAKRRTHDKAVAPTMAICPNCGAWHIYHTVCG
                     ECGYYRGKLAIEKEAAV"
     gene            2506..3510
                     /locus_tag="ACZPB4_13470"
     CDS             2506..3510
                     /locus_tag="ACZPB4_13470"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HIR1099258.1"
                     /translation="MDKINAVITGVGGYVPEDVLTNEDISKMVDTTDEWIMTRVGIKE
                     RRILKGEGVGLSYMGIRAVKQLLEKTNLNPEEVEVVLTATTTPDHHFPTTSSIIAYHT
                     GCKNAMTFDMQGACAGFLYALETGANYIRSGRYKKVVVVSGDKMTSITDYQDRSTCPL
                     FGDACGAVLLEPTTEEFGVLDTILRTDGVGYPHLIMKSGGSAYPPSHETVDNREHFVY
                     QDGRVVFKYAVSYMADVAAEIAEKNGLTHDDIAWIVPHQANLRIIDATAKRLGVDMDK
                     VMINIQKYGNTSAGTIPICLWEWENQLKKGDNLILAAFGAGFTWGAVYLKWGYDGKKA
                     "
     gene            3494..4384
                     /gene="era"
                     /locus_tag="ACZPB4_13475"
     CDS             3494..4384
                     /gene="era"
                     /locus_tag="ACZPB4_13475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005645680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HIR1099259.1"
                     /translation="MEKKHKSGFVNIVGNPNVGKSTLMNRLVGERISIITSKAQTTRH
                     RIMGIVNTDDMQIVYSDTPGVLRPNYKLQESMLNFSQSALGDADVLLYVTDVVETIDK
                     NNEFLARVQSIECPVLLLINKIDQTNQPELEKLVAQWKELLPKAEIIPISALSNFNID
                     YVKRRVEELMPDSPPYFEKDALTDKPARFFVTEIIREKILLYYQKEIPYAVEVVVELF
                     KEDDELIHIKALIIVERDTQKGIIIGHQGQALKKVGAMARKDIERFFGKKVFLEMFVK
                     VEKDWRNRDNILKNFGYQLD"
     gene            4409..5722
                     /gene="der"
                     /locus_tag="ACZPB4_13480"
     CDS             4409..5722
                     /gene="der"
                     /locus_tag="ACZPB4_13480"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008661792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HIR1099260.1"
                     /translation="MGNIVAIVGRPNVGKSTLFNRLTGTRQAIVNEEAGTTRDRQYGK
                     VEWTGKEFSLIDTGGWVVNSEDVFEEEINKQVKVAIEEADVILFVVDVLNGITDLDME
                     VAQILRRCKRPVIVVANKADNYDLHPASAEFYSFGLGDPFCISAINGSYTGDLLDKIV
                     ATLPEEKVEILEEELPRIAIIGRPNAGKSSLINAFIGEDRHIVTDIAGTTRDSIYTKY
                     NKFGLNFYLVDTAGIRKKGKVNEDLEYYSVIRSIRAIENSDVCVLMLDATRGIESQDM
                     NIFSLVQKNKKGLVVCVNKWDLIEDKSQKVIDSYTTAIRERLAPFTDFPILFISALTK
                     QRILKVLETAKEVYENRSKRVPTAKLNEVMLPIIENYPPPAWKGKYIKIKYITQLPAG
                     SVPSFVFFCNLPQWIKDPYKRFLENKIRENWDFTGTPINIFIREK"
     assembly_gap    5727..5826
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(6099..6950)
                     /locus_tag="ACZPB4_13485"
     CDS             complement(6099..6950)
                     /locus_tag="ACZPB4_13485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6261 family protein"
                     /protein_id="HIR1099261.1"
                     /translation="MSTYTKIKTLPLSLFNNAEYLSFMNHVLDLANGNSGDGDSESPD
                     EISLLTGNDGIPELGLTKEFLETYEADLLAMADVVDESRTSQETEQMTLHDTNRDNLA
                     IYIITRISRAGTLPLEAERDAGKYLYKVIKPYNGVARLPMAQETAKIKGLLLDLRKDE
                     NKPYVTTLGLDAYLAELEKENNAYDRLSQQRVQNRTTSKKESGANLRKRIDMYYDDLT
                     LLAQSHSIAKPSEKATAFIAALNQLIAETTAAYNQRMAASKKPAPAPEPTPEPTPGGD
                     SESPDEI"
     gene            7574..8881
                     /locus_tag="ACZPB4_13490"
     CDS             7574..8881
                     /locus_tag="ACZPB4_13490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099262.1"
                     /translation="MRKLVYLLGLLFFMACGEDAKEGIIPEPDVPYDYSEFGGYHVKD
                     TVGYDMATLEFYSSNDTAWIYAIKGQKVWFGMFNDNTKEQITEWKASSSEESDYTSSF
                     LGNPFKVGDKYVCFMKIAPELYKPFLLKEESAISLKEREASWGSENFFSVREFGENIL
                     VYHPHFYGNLLYSSEGVEVINSVAFQDDPESDNEYLSGFKNDKVWFGIYENGELREEY
                     TGENVYDRNIKINKGYGEYEEYFVKALSFGYSSGLLKTEWGYVFYPTIKDSESGGYIH
                     DMFFCNGGKMFPVFVGTYYLDIRNWYDGSVLMGNKVVFSPEGKRLIEFEDNDLGDDRM
                     LSVFCKEPSSYTHIIRLMHARMWADYTVVTIDKYDLESKNSLWSVNVDALGECAVNSK
                     FVAKVLGKDKNIWTMEVSVISFEGQEKISNFKLNTDTGEIIYL"
     gene            complement(9172..9480)
                     /locus_tag="ACZPB4_13495"
     CDS             complement(9172..9480)
                     /locus_tag="ACZPB4_13495"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HIR1099263.1"
                     /translation="MVQWGRFRSGLLVQEWGGGLRQGRRFASGFVLTNRFTEKSDIDL
                     VVDFDKEVEQVNYVNNFFDLRNALSAIFHREIDLLEDKSIRNPILRKNIDNTKLLIYG
                     "
     gene            complement(9420..9671)
                     /locus_tag="ACZPB4_13500"
     CDS             complement(9420..9671)
                     /locus_tag="ACZPB4_13500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2442 domain-containing protein"
                     /protein_id="HIR1099264.1"
                     /translation="MTEDIDLICVTGVEYVKGYTMRLEFSNGKVKLVNFLPLLKGKLF
                     EPLKDLRNFVQFGLTHWALEWYNGADFAPDYLYRNGVEA"
     gene            9856..10449
                     /locus_tag="ACZPB4_13505"
     CDS             9856..10449
                     /locus_tag="ACZPB4_13505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099265.1"
                     /translation="MFTPSMTNEEIEAVAYKDFLEIRGRVEIAKDKFVQRVRCTPPGF
                     WALHSLQETHTLQTRSKNTWTVYFYYLYTTPAGAVKVSSMIYTSLPGDEGTDYLFMNN
                     LDRFRLERVSSHFSQQYEERYIDPNQIQLNGLLPAIYFMRTAGDRKIAPYTLDTWTEE
                     EKKDKYLFVSEQGTMEAKLEGRVETYLTFRKPEQSGD"
     gene            complement(10510..12861)
                     /locus_tag="ACZPB4_13510"
     CDS             complement(10510..12861)
                     /locus_tag="ACZPB4_13510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005853858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 3 C-terminal
                     domain-containing protein"
                     /protein_id="HIR1099266.1"
                     /translation="MNKLLMGACLTMAMQVGHSQTLPQLGKDPIEKIVAAMTAEEKVS
                     LLVGTGMPGFGGQSAVVGSTQNIVPGAAGTTFPIERLGIPAIVVADGPAGLRISPTRE
                     GNEATYYCTAFPVATLLASTWNTALVKNVGNAMGDEVKEYGCDVLLAPALNIHRSPLC
                     GRNFEYYSEDPYLTGRIATAMVNGIQSNGVGTSIKHFAVNNQETNRTGTDARLTPRAL
                     REIYLRGFEMVVKEASPWTVMSSYNKINGEYASESRDLLTTILRDEWGFSGLVMTDWF
                     GGKNAPAQIHAGNDLLMPGRPDQKEALLKALEDGSLSIDDVDTDVTRVLRLILQAPRF
                     AQYAYSDKPDLKAHAEVTRASASEGMVLLKNTNNALPLAPGIKKIAAYGTTSYDFIAG
                     GTGSGDVNEAYTVSLVEGLENAGYTMDAEVKAIYEKYSTEEKAKQPKETSPAAAFFNH
                     PRIPEFVPDAAGLAAKAKEADIAFVTIGRSSGEFQDRKIEGDFNLTENERALIQSVSD
                     AFHKEGKKVVIILNIGGVIETASWKSEPDAILLAWQAGQEGGNTVADILSGKVNPSGK
                     LPMTFPVSIADVASTKNFPDASGIDLKEMLAGFMGGGPEHTDRKNIDYTNYEEGIYVG
                     YRYFDTFGVPVSYPFGYGQSYTTFNYSSLKVFMGDTDYSISCTITNNGPVAGKEVVQL
                     YISAPGKSMDKPAKELRGFAKTQLLQPGESREIIFKVKDTDLASFDESASHWVVESGK
                     YEAQIGSSAADIRLRDSFNVKGRVTEKVHAVLLPGERIDLLKR"
     gene            complement(13038..14813)
                     /locus_tag="ACZPB4_13515"
     CDS             complement(13038..14813)
                     /locus_tag="ACZPB4_13515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4091 domain-containing protein"
                     /protein_id="HIR1099267.1"
                     /translation="MKNTFILCAFLALSSFTVAQQSEKYPLGDYTELTDTKPHDSDEI
                     WDKLSAPTQLSWGTTDIRYPKLSIPDVKKSNRWQTKAWKGERVNAQAVLWTKVGLEDA
                     SITVSDLKSGSSIIPSSAITTNFVRYVMTDELNKDRKGGCGHRENKAEWDSSVVADVL
                     DIVKIRDIKARTTQPIWMNIWVPQSAKAGKYKGTLTVTGKNASPMELQIEVDVLNRTL
                     PAPKDWAFHLDLWQNPYSVARYYQVPLWSKEHFDAMRPIMKMLANAGQRAITTSIMHK
                     PWAGQTEDHFDSMITRIKKIDGTWAYDYAVFDKWVAFMMNEIGIDDMISCYTMIPWAL
                     SFDYYDEATNRVQFLNTKPGDAAYADYWGTFLKDFSRHLREKGWFEKTAISMDERPME
                     AMREAIKVIKQADPEFKITLAGNYHPEIQSDLYYLSIPYGHKFPEDVKAARDKAGQIS
                     TVYTCCAEAFPNTFTFSDPAEAAWTVLHAVAGGYDGYLRWAVNSWTADPLRDSRFRTW
                     AAGDTYSIYPGPRSSIRFERLVEGIQDCEKIRILREELTTKGAKGKLEKLNKTVAKIT
                     PEGLSETQESATQMVNEIHKLLNTL"
BASE COUNT         3721 a         3109 c         3884 g         4045 t
ORIGIN      
        1 attaaggtgg ctatagcacg agggatccac ctcttcccat tccgaacaga gaagttaagc
       61 ctcgtcacgc cgatggtact gcgtaacagt ggaagagtag gcagccgccg tcttgagaaa
      121 ggcgaaagcc ggaagagaga ggagtcagtc gaaagattgg ctcctttttt tgttatatac
      181 actagccgtt gtagagacgt ggtgtgcctc gctcactaca gactgatagt attgttacta
      241 ttgctagggg atgagacgca gcacgctgcg tctttacaac tgggtgagat ttcattgttt
      301 gctgaatcgg gaacaataaa gttcgtatct tgccgttata ttaagaattc accgaatgat
      361 tctgatttat gagcagcata tatgattctc gtcaaagatg gaaattaggc tttatttttg
      421 ccgcagtatt gatcgctatg gcttctgtgg tagtatcgga tctcttgatt aaagatctgg
      481 cccgagaaga gcgtcagaag atcgaggttt ggagtgaggc aacccgggtc atgaccagtg
      541 agaatccaag ccttaatatg aatcttatcc taaaaatcat ccaagggaat acttctattc
      601 ctgttatatt atgcagtgag acggatagcg tggtttctta taataatata gagattccgg
      661 aaaagaatgt agcgcagttc atgacgaata aggttaagga actgagaacc aaaaatcctc
      721 cgatcgtaat tgacatggag gatggtactt accaatattt atattacgat gattcgatta
      781 tcttaaagcg actgcttgtt tatccctatg cgcaattatc agttgtattt gtttttatat
      841 taatcgcttt tttagccttg gctagtacaa agaaggcaga acagaataaa gtgtgggtgg
      901 ggttatcgaa agagacggct caccaattag gaacgcctat atcctcgcta atcgcttggg
      961 ttgaatattt gcgaacgaaa gatatagatc cttctctatt gacagagatg gataaggatg
     1021 tgaaacgctt acaaacgata gcggagcgtt tctctaaaat cggttcagat ccagatccgg
     1081 ttccgacaaa tatcgtggaa tccatccgtg cggctttggg atacatggag acccgtattt
     1141 cctcgaaggt gaaaatcaat acgtatttac cggagcggcc gatattggtc ttaatgaatg
     1201 attccctgtt cgcttgggta atcgagaacc tgacgaaaaa tgcggtggac gccatggagg
     1261 ggcagggtga gatttcgcta aaagtagagg aaagagagaa ggtcgtgctg atcgatttgg
     1321 ctgataccgg aaaaggtatc ccgaaatcaa aattcaagac ggttttcaat ccggggtata
     1381 cgaccaagaa acgtggctgg ggattaggct tgtccttggt aaagcgcatt atcgagtcct
     1441 tccaaggagg aaagattttc gtgaagagtt cggagctagg gaaagggacg acttttcgta
     1501 taaaattgaa gaaatataag ggttaaatcg tattatagga aaaaataagc ataaaggtat
     1561 tgtttttgta tttagttttt tcgtaccttt gcaaggtttt tacactaaaa ggctttgggg
     1621 aaatttaaat tatataatgt agatttgaaa aatctctctc cgggagtaca cgaattcgag
     1681 tatcttttgg agaacaagtt ttttgtggac attgacggaa ccgaggtcca gaagggcaaa
     1741 gtgaaggttc atcttaccgt aaaacggtcg tcaatgatgt ttgagatgaa ctttcagata
     1801 gaaggggttg ttgttgttcc atgcgataga tgcttggacg atatggaaat tcctattgat
     1861 acccacaatc gtctggtggt aaaattcggc aaggaatatg ccgaggaaag tgatgaggtt
     1921 gtcgtgatac cggaagagga gggcgctatt aatttggcgt ggttcctgta tgagtttatc
     1981 gctttggcgg ttcccatgaa gcatgtacat gcgccgggta aatgtaataa ggcaatgtcg
     2041 tctaaattga agaaacatac cgccagaagt tcggatgaga ccgaagacga ttttgaggat
     2101 gacatgggag gtgatgattt ggcgttggaa gatgacggaa acgctagtcc tgccgatcct
     2161 cgttgggatg ctctgaaagg tttgctagag aatgataaca attaaataaa taaaacaatg
     2221 gcacatccta aaagaagaca aggtaagaca agaacagcca agagaagaac tcatgacaag
     2281 gctgtagctc caacaatggc aatttgcccg aactgtggcg catggcacat ctatcacaca
     2341 gtatgtggtg agtgcggtta ttacagaggt aaattagcga ttgaaaaaga agctgctgtg
     2401 taagtttgtc aacttatatg gtttgatgaa caaaagaaat agccctaaaa gtttttttag
     2461 ggcttttttt taattgggat aagtagtcct tttattttta aagttatgga taagataaat
     2521 gcggttatca caggagtggg tggatacgtt cctgaagatg tattgacgaa tgaggatatt
     2581 tccaagatgg tcgatacgac ggatgagtgg atcatgactc gtgtgggtat taaggagcgc
     2641 aggatattga aaggggaggg cgtaggactc tcttacatgg gtatacgggc cgtgaagcaa
     2701 ttgctcgaga aaacgaacct gaatccggaa gaagtagagg ttgtcttgac cgctacgact
     2761 accccggatc atcatttccc gacaacttct tctatcatcg cttatcatac aggttgcaag
     2821 aatgcgatga cttttgatat gcaaggtgcg tgcgcaggct tcttgtatgc tttggagacg
     2881 ggcgctaatt atattcgctc ggggcgttat aagaaggtgg ttgtcgtatc gggtgataag
     2941 atgacatcta ttacagatta tcaagatcgt tctacttgtc ctttgttcgg ggatgcttgc
     3001 ggagcggtct tgctggagcc aactaccgag gagttcggtg tcttggatac tattttacgg
     3061 acagacggcg taggctatcc gcatctgatc atgaaatcgg gcggctcggc ttatcctcct
     3121 tctcacgaga cggtggataa ccgtgagcat ttcgtttatc aagatggacg tgtggtcttc
     3181 aagtacgcgg tttcttatat ggcggacgtg gccgctgaga tcgcggagaa gaatggcttg
     3241 acgcatgatg atatcgcatg gatcgttcct catcaagcga acctgcggat tatcgacgct
     3301 acggcgaaac gcttaggcgt agatatggat aaggtgatga tcaacatcca gaaatacggc
     3361 aacacaagcg ccggtacgat tcctatttgt ctatgggaat gggagaatca attgaaaaaa
     3421 ggagataacc tgatcctcgc cgcttttgga gcgggcttta cgtggggagc ggtttatctg
     3481 aaatgggggt atgatggaaa aaaagcataa atcgggtttt gtcaatatcg ttggaaaccc
     3541 aaacgtaggt aagtctacgt tgatgaatcg tttggtcggg gagcggatct ctattatcac
     3601 ctcgaaggcg caaacgacaa ggcatcgtat tatgggtatc gtgaataccg acgatatgca
     3661 aatcgtgtat tctgacacgc cgggagtctt gcggccgaat tataagttgc aggaatccat
     3721 gcttaatttc tctcaatccg ccttaggcga cgccgacgtg ctgttgtacg tgacggatgt
     3781 cgtcgagacg attgataaaa ataatgagtt cctagcacgg gtacagagta tagagtgtcc
     3841 ggttctcttg ttgatcaata aaatcgacca gaccaatcag ccggagctgg agaagctcgt
     3901 ggcccagtgg aaggaattgc ttccgaaggc cgagatcatc ccgatctctg cgctttcgaa
     3961 tttcaatata gattacgtga agcgtcgggt ggaggagttg atgcctgatt ccccgcctta
     4021 tttcgagaaa gacgccttga ccgataaacc ggcccgtttc ttcgtgacag agatcattcg
     4081 tgagaaaatc ttgttatatt atcagaagga aataccttac gcggtagaag tggtcgtcga
     4141 gttgttcaag gaagatgatg agctgatcca tatcaaggcg ctgatcatcg tggagcgtga
     4201 tacccagaaa gggatcatca tcgggcatca agggcaagca ttgaagaaag taggtgctat
     4261 ggcccggaag gatatcgaac gtttcttcgg gaagaaggtg tttttggaaa tgtttgtcaa
     4321 agtggaaaaa gactggcgta accgtgacaa catattgaag aacttcggtt atcagctgga
     4381 ctaataatag catacgaaag gagaatttat gggaaatata gtagcgatag tggggagacc
     4441 caatgtaggt aagtccaccc ttttcaaccg gttgacgggt acccgtcagg cgatcgtgaa
     4501 cgaggaggct ggtactaccc gtgaccgtca gtacggcaag gtggagtgga ccggcaagga
     4561 gttttcgctg attgacacag gcggatgggt ggttaactcg gaggatgttt tcgaggagga
     4621 gatcaacaag caggtaaaag tggctatcga ggaggcggac gtgatcttgt tcgtcgtcga
     4681 tgtattgaat ggcatcacgg atctggacat ggaggtggcg cagatcttgc gtcgttgcaa
     4741 gcggccggtg atcgtggtgg cgaacaaggc ggataattat gatctgcatc cggcctcggc
     4801 ggagttttac tcgtttggct tgggagatcc tttctgcatc tcggccatca atggttctta
     4861 taccggggat ttgctggata agatcgtggc gacgttgccc gaggagaagg tggagatact
     4921 ggaggaggag ttgccccgta tcgcgattat aggacgcccg aacgcgggaa aatcttctct
     4981 tatcaatgct tttattggcg aggatcgtca tatcgttacc gatatcgcag gcacgacccg
     5041 tgattccatc tacacgaaat ataataaatt cggcttgaac ttctatttgg tggatacggc
     5101 gggtatccgt aagaagggga aggtgaatga ggacttggag tattactcgg tgatccgttc
     5161 gatccgcgcc atcgagaact cggatgtctg cgtgctgatg ttggacgcta cgaggggtat
     5221 cgagagccag gatatgaata tcttctcgct ggtgcagaag aataagaagg gattggtggt
     5281 ttgtgtgaat aagtgggact tgatcgaaga taagagccag aaggtgatcg actcgtacac
     5341 gaccgctatc cgcgagcgtc tggctccgtt taccgacttc ccgatcttgt ttatctccgc
     5401 tctgacgaaa caacgtatcc tgaaggtgct agagaccgcc aaggaggttt acgagaatcg
     5461 ctccaagcgt gtccctacgg ccaagctgaa cgaggtgatg cttccgatca tcgagaatta
     5521 tcctccccca gcatggaagg gtaagtatat caagatcaaa tatatcaccc agctcccggc
     5581 gggcagcgtg ccttctttcg tgttcttctg taacttgccg caatggatca aggacccgta
     5641 caaacgtttc cttgagaaca agatacgcga gaactgggat tttaccggta cgccgattaa
     5701 tatatttatc cgggaaaagt aaatacnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     5761 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     5821 nnnnnnatcc ttcctgcctt cacgtcctcc aaggcctcgt ccaatccgga tttcttctgt
     5881 gccttcacct tgccttccag cgaagtgatg aatttcttca agatgtcggc gtatttctcg
     5941 gggatggtta cctcgaatgt ctttaatgat gtcgttgtct ccatatcgct ctgttttagg
     6001 aatttccttt gcgaatatac ggaataaaaa gagaagggga attgttttcc ttctcttttt
     6061 atttcccgct tccgcgtcgg gagggaggga cgtgacggtt agatctcgtc cgggctctcg
     6121 gagtctccgc cgggcgtagg ctcgggtgta ggctcgggag cgggcgccgg tttcttggag
     6181 gcggccatgc gctggttgta ggcggcggtg gtctcggcga tcagctggtt gagggcggcg
     6241 atgaaggcgg tcgctttctc ggacggcttc gctatgctat gggactgggc cagcagggtg
     6301 agatcgtcat aatacatgtc gatccgcttg cgcaggttgg cgccgctttc ctttttggag
     6361 gtggtccggt tttggacgcg ttgctgcgac aggcggtcgt aggcgttatt ctctttctcc
     6421 agttcggcga ggtaagcgtc gaggccgagc gtggtgacgt acggcttgtt ctcgtccttg
     6481 cgcaaatcca gcaagaggcc ctttatcttg gcggtctcct gcgccatggg gaggcgggcg
     6541 accccgttat agggcttgat gaccttgtat agatacttgc ccgcgtcacg ctcggcctcc
     6601 aacgggaggg taccggcccg tgagatgcgg gtgatgatat agatagcgag gttgtcgcgg
     6661 ttggtatcgt gcaaggtcat ttgctcggtc tcctgcgagg tgcggctctc gtccaccacg
     6721 tcggccatgg cgaggaggtc tgcctcgtag gtctcgagga attctttggt gaggcccagc
     6781 tcggggatgc cgtcgttgcc ggtcagcagg gagatctcgt cgggggactc ggaatcgccg
     6841 tcaccgctat ttccgttggc taggtcgagg acgtggttca tgaaggagag gtactcggcg
     6901 ttgttgaaaa gagagagcgg aagtgtcttg atttttgtgt aagtactcat ggtaaatttg
     6961 atttagagtt taaaaacttc tctaagttag ggatatttgc tgaataaggg cttcttaggc
     7021 ctaaaaaatg gggattgaat ggcgcgaata atcatcttag gcctaagaaa tggcttttca
     7081 agggtgaaaa taggcttttt aggcctaaga aatggtttcg cggccttgaa agtcccttcc
     7141 taggccaagg aaatcacttt tcacggttga aaaactatct tttagcccta agaagtcatt
     7201 tttcaccctt cgagggcatt tcttagggct aagagacatt aagaatctga ttgttttgcg
     7261 aatgttttaa aaaaacacga tcttcgcgat gtattggaaa aataacgtag aagcgtttcg
     7321 atattatctt gtactggaat ctggacaatt tcattaccca agataatagg aaaatggctc
     7381 ctgcgcttta tctgttatat acctacccat tcatggatag attatatacc tgcataaggc
     7441 gtgggatcat tgtcttatta ttgggtaagg gcagtccaga gcctcagtac agtgatagac
     7501 aatggtctcc acgcttcttt tatttgttaa ccgcctaccg gaggaggcac gggaggaaga
     7561 atgtgataaa gatatgagaa aattggttta tttgttaggt ttattatttt ttatggcctg
     7621 cggagaagat gctaaagagg gaattattcc tgaacctgat gttccttatg attatagtga
     7681 gttcggcggc tatcatgtga aggatactgt cggttacgat atggcgacgc ttgagtttta
     7741 ctcatctaat gatacggctt ggatttatgc gattaaaggt caaaaggtgt ggtttggtat
     7801 gttcaatgac aatacgaaag aacaaattac ggaatggaag gcctcctcaa gtgaggaatc
     7861 agactacacc agttcatttc ttggtaatcc atttaaggta ggagataaat atgtatgttt
     7921 catgaagatt gctcctgagt tatataaacc ttttttgttg aaagaggaaa gcgctatctc
     7981 tcttaaagaa cgagaagcca gttggggaag tgagaacttt ttttcagtta gagagtttgg
     8041 agagaatata ttggtttatc atcctcattt ttatggtaac ctattatatt catcagaagg
     8101 agttgaggtc ataaattctg tggcttttca ggatgatcct gaatctgata atgagtattt
     8161 atcaggtttt aagaatgata aagtgtggtt tggtatatac gaaaatggtg aattgcgaga
     8221 agaatatacg ggcgagaatg tttatgatag aaatataaag atcaataaag gatatggcga
     8281 atacgaggaa tattttgtga aggccttgtc tttcggttat tcgagcggtt tgttgaaaac
     8341 agaatggggg tatgtatttt atcctacgat caaagattct gaaagtggtg gttatattca
     8401 tgatatgttt ttttgtaatg gagggaaaat gtttccggtc tttgttggaa catattattt
     8461 agatataagg aattggtatg atggaagtgt tctaatgggt aacaaagtag tcttctctcc
     8521 ggaaggtaag aggctgatag aatttgaaga taatgatcta ggagatgata ggatgttgag
     8581 tgtattttgt aaagaaccta gttcttatac tcatataata aggttgatgc atgcaaggat
     8641 gtgggctgat tatacggtgg ttactatcga caaatatgat ttggaatcaa agaattctct
     8701 ttggagcgtg aatgtggatg cgctgggaga atgtgctgtg aatagtaaat ttgttgctaa
     8761 ggtattggga aaagataaaa atatttggac gatggaagtg tctgtgatat catttgaagg
     8821 acaagaaaag atctcgaatt ttaagttgaa tacggatacg ggtgagatta tctatttata
     8881 atcattatct gtgataagat ccttttaacg gattagtgaa aatatctata tgaccataaa
     8941 accttctccg tcaaatctta ttgtatgaaa tggagaaggt tttatagttc catatatttt
     9001 atttttccaa tatccctatc atgcccccct tcagcaccgg gatatggttt atgataagcg
     9061 tccaaagaaa atcgggatcg atctttagta tcctattttg gcctaccctc aaagtaactc
     9121 tcagtctctt cgatagaaag tagcacatca taaagatgtt tctcgatata ttcatccata
     9181 gatcagcaat tttgtattat caatattctt tcttaggatc gggttccgga tcgacttgtc
     9241 ctctagcaag tcgatctccc ggtggaagat ggcagataag gcgttgcgca gatcgaagaa
     9301 attattcacg taattcacct gttccacctc tttgtcgaaa tccaccacaa gatcaatatc
     9361 gctcttctcc gtgaagcggt tcgtgaggac gaaacctgaa gcgaaccgcc ggccttgtct
     9421 taagcctcca ccccattcct gtacaagtaa tccggagcga aatctgcccc attgtaccat
     9481 tcgagcgccc agtgtgtgag cccgaactgg acgaaattcc ggaggtcttt caatggctcg
     9541 aaaagtttcc ctttcagtaa agggaggaag ttcactaatt tcaccttacc gttgctaaat
     9601 tccaatcgca tggtatagcc ctttacatat tccacgccag tgacgcatat taaatctata
     9661 tcttcagtca taactttttc tcttttaaat gggtcttagg ggattttcat cacgaatata
     9721 tggaataaaa aagataaggg tacgagttcg tctctctttt ttgtctttct ttcatccaca
     9781 tttccttgaa acccttggaa tccccattta taatcgtacc tttatgtctc tttaccttaa
     9841 aaattaaaaa taatcatgtt tacgccatca atgacaaacg aggaaataga ggcagtggcc
     9901 tataaggact ttctggagat ccggggaaga gtggaaattg cgaaggataa attcgtacaa
     9961 agggtgagat gcacgccccc gggattttgg gccttgcatt ccttacagga gacacatacc
    10021 cttcaaaccc gctccaagaa tacatggact gtatatttct attatttgta cacgacaccg
    10081 gccggtgccg tgaaagtctc atctatgatt tacacctccc tgccgggaga tgaaggcacg
    10141 gattacctgt ttatgaataa tctcgaccgc ttccggctgg agagggtgag ctcgcatttc
    10201 tcgcaacaat acgaggaacg ctatatcgac ccgaaccaga tccaactgaa cggccttctg
    10261 cccgctatct atttcatgag gactgccggc gaccggaaga tcgctcccta cactctcgat
    10321 acgtggaccg aggaggagaa gaaggacaaa tatctcttcg tgtcggagca aggaaccatg
    10381 gaggcgaagc tggaggggcg tgtggagacc taccttactt tcaggaagcc ggaacaatcg
    10441 ggtgattaaa taagtagagg gcgaggttga taccccgccc tcccgataac taggtagata
    10501 cctccgggct tatcttttca gaagatcgat cctctcgccg ggcaacagta ccgcatgaac
    10561 cttctccgtt acccgcccct tcacgttgaa ggaatccctt aggcggatgt cggcggcgga
    10621 ggaaccgatc tgcgcctcat atttaccgga ctctacgacc caatgactgg cgctctcgtc
    10681 gaaggaggcc agatccgtat ctttcacctt gaagatgatc tcacggctct cgcccggctg
    10741 gaggagttgg gtcttggcga aacctctcaa ctctttcgcc ggtttatcca tgctcttgcc
    10801 gggggcggag atatatagct ggaccacttc cttcccggct accgggccat tgttcgtgat
    10861 cgtgcaactg atgctgtagt ccgtatcacc catgaacact ttcaagctcg aataattgaa
    10921 agtcgtatac gactgtccgt agccaaacgg ataggagacg ggcacgccga acgtatcgaa
    10981 gtaacggtag cccacgtaga taccctcctc gtagttggta tagtcaatat tcttacgatc
    11041 cgtatgctcc gggcctcctc ccatgaagcc ggctaacatt tctttcaggt cgatacccga
    11101 agcgtccggg aaattcttcg tggaggctac gtcggcgatg ctcacgggga aagtcatcgg
    11161 gagcttaccg gaaggattca cctttccgga caggatatcg gctaccgtgt tacccccttc
    11221 ctgcccggct tgccaagcca ataggatggc gtccggttcc gatttccagc tggcggtctc
    11281 gatcacgcct ccgatattca agattatgac caccttcttc ccttctttat ggaaagcgtc
    11341 ggaaaccgat tggatcaacg ctcgctcatt ctccgtcagg ttgaaatctc cctcgatctt
    11401 ccggtcttgg aactctcccg agctacggcc tatcgtaacg aaggcgatat ccgcctcttt
    11461 cgccttagcg gccagccctg cggcatccgg tacgaactcc gggatacgag ggtggttgaa
    11521 gaaagcggcg gcgggactcg tctctttcgg ctgtttcgcc ttttcctcgg tactgtattt
    11581 ctcgtagatg gctttcactt cggcgtccat ggtataaccg gcgttctcca gaccttccac
    11641 gagggatacg gtataagcct cgttcacgtc gccgctgccg gtgcctccgg cgataaaatc
    11701 gtacgaggtg gtaccgtaag ccgctatctt cttgataccc ggggccagcg gcaaggcatt
    11761 attcgtattc tttaataaaa ccataccttc ggaagcggac gcacgggtta cctcggcgtg
    11821 agctttcagg tccggtttgt cggaataggc gtattgggca aagcgggggg cttgaaggat
    11881 cagtcgtaat acacgggtta cgtccgtatc cacgtcgtcg atagagagag aaccgtcctc
    11941 aagcgctttt aggagggcct ctttctggtc cggccggccg ggcatcagca gatcgtttcc
    12001 ggcgtggatc tgggcggggg cgttcttgcc gccaaaccag tcggtcatga caaggccgct
    12061 aaaaccccat tcgtcacgga ggatggtcgt tagcaaatca cggctttcgg aggcatactc
    12121 accatttatc ttattgtagg aagacatgac cgtccacggg cttgcctctt ttacgaccat
    12181 ctcgaaacct cttaggtaaa tctcccgcaa ggcacgaggg gtgaggcggg catccgttcc
    12241 cgtccggttg gtctcttgat tattgacggc gaaatgcttg atggaggttc ccacgccatt
    12301 gctttggata ccgtttacca tcgctgtcgc tatccggccc gtcaagtagg gatcttcgga
    12361 ataatactcg aagttacgtc cgcagagagg gcttcggtgg atattcagcg cgggggccaa
    12421 gagtacgtcg caaccgtatt ctttcacctc gtcgcccatg gcgttgccta cgtttttgac
    12481 caatgcggtg ttccatgtgg aggctagcaa ggtagcgacc gggaatgccg tgcaataata
    12541 ggtcgcctcg ttcccctcgc gagtcgggga gatacgtaat ccggcgggac cgtcggccac
    12601 tacgatagcg gggattccca gacgttcgat cgggaaggtc gttccggcgg ctcccggcac
    12661 tatattttgc gtgctgccga ctacggctga ttggccgccg aacccgggca ttccggttcc
    12721 gactaacagg gatactttct cttcggcagt catggcggct acgattttct cgataggatc
    12781 tttacccaat tgcggcaagg tttgggagtg ccctacttgc atggccatcg taaggcatgc
    12841 gcccattaat agtttgttca tatagaatgg tttttgtgtt tttcagtgcc ccaaaagtag
    12901 gcgaaggaat cgaggcggac aaagaaaaag aaaggtatcg gaggtaagga tttcgttttt
    12961 tgatgaatat caaacattgt aggggtttga tgatatattt aggggacgcc gactgcgcag
    13021 tcggcgtcct gtactattta taatgtattc agaagtttat gaatctcatt aaccatctgc
    13081 gtagcggatt cttgtgtctc ggataaacct tccggagtga tcttggcaac cgtcttgttc
    13141 aacttctcga gtttgccttt agctcctttc gttgtcagct cttcccggag gatgcggatc
    13201 ttctcgcaat cttgtatacc ctcgaccaaa cgttcgaagc gaatgctact gcgtggaccg
    13261 ggataaatac tgtatgtatc gcctgccgcc caagtgcgga aacgcgaatc acgcagagga
    13321 tcggcggtcc agctattaac tgcccaacgt agataaccgt cgtaaccacc agctacggcg
    13381 tgcaagaccg tccatgccgc ttccgccggg tcggagaagg tgaaggtatt cgggaacgct
    13441 tccgcgcaac aggtataaac ggtactgatc tgtcccgctt tatcacgggc agcctttacg
    13501 tcttctggga atttatgccc atagggaata cttaaatagt ataagtccga ttgaatttcc
    13561 ggatgataat ttccggccag cgtgatcttg aactccggat cggcttgctt gataaccttg
    13621 atcgcttcac gcatcgcctc catcggacgc tcgtccatag agatggcggt tttctcgaac
    13681 caacctttct cgcgaaggtg gcgggagaaa tcttttagga aagtacccca atagtctgcg
    13741 taagcggcgt cacccggttt cgtgttgagg aattgtacac gatttgtcgc ctcgtcgtaa
    13801 taatcgaaag ataaagccca agggatcatg gtgtagcaac tgatcatatc atcgataccg
    13861 atctcgttca tcatgaatgc cacccatttg tcgaagacgg cgtaatcata tgcccaagtg
    13921 ccgtctatct tcttgatccg ggtgatcatg ctgtcgaaat gatcctcggt ctgtccggcc
    13981 caaggtttat gcatgatact ggtggtgata gcgcgctgtc cggcgttcgc caacatcttc
    14041 atgatcgggc gcatagcgtc gaaatgctct ttactccaaa gaggaacttg gtagtaacgg
    14101 gccacggaat acgggttctg ccataagtcc agatggaaag cccagtcctt cggggcggga
    14161 agtgtgcggt tcaatacgtc cacttctatt tgtaattcca tgggggaggc attttttccc
    14221 gtgacagtca atgtcccttt atatttaccg gcttttgcgg attgaggtac ccagatattc
    14281 atccagatcg gctgggtggt gcgtgccttg atatcacgga tctttacgat atccaataca
    14341 tctgctacga cggaggaatc ccattccgcc ttattctctc ggtggccgca accgccttta
    14401 cggtctttat tcaattcatc ggtcatgacg tatcggacaa agttcgtcgt gattgcggag
    14461 gatgggatga tggaagaacc gctctttaag tcgctcacgg tgatagaggc atcctcgagt
    14521 cccaccttgg tccataacac ggcttgtgcg tttacccgtt cccctttcca tgctttcgtc
    14581 tgccagcgat tgcttttctt gacatcggga atactgagtt tcggatatcg tatatcggtc
    14641 gtgccccagc ttaattgggt tggggccgat aacttgtccc agatctcgtc gctgtcatgc
    14701 ggtttcgtgt cggtcaattc cgtatagtcg cctagcgggt atttctcgga ttgctgggct
    14761 acggtaaaag aacttagtgc cagaaaggca caaaggatga aagtgttttt catacgattg
    14821 cttattttag aatattaact agggcaaaga taggaatta
//
LOCUS       DBMDTB010000096        14657 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_1286_length_14657_cov_10.200055, whole genome shotgun
            sequence.
ACCESSION   DBMDTB010000096 DBMDTB010000000
VERSION     DBMDTB010000096.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 14657)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 14657)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14657
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1286_length_14657_cov_10.200055"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..627
                     /locus_tag="ACZPB4_13520"
     CDS             <1..627
                     /locus_tag="ACZPB4_13520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015252 - proton channel activity
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MotA/TolQ/ExbB proton channel family protein"
                     /protein_id="HIR1099268.1"
                     /translation="EAEINVIDLAFKGGWIMVVLLLLSLMAIYIFVQRLIIIRRAGKE
                     DETFMNRIKDYIHEGKVDSALNLCRSTNTPSARMIEKGITRLGRPMNDVLVAIENVGN
                     LEIAKLEKGFPLIATTAAGAPMLGFLGTVTGMVRAFFDMANAGTNVDVSLLSGGIYEA
                     LVTTVGGLVVGIITLFAYNYLVSQVDNVVNKMEARTMEFMDLLNEPAN"
     gene            719..1129
                     /locus_tag="ACZPB4_13525"
     CDS             719..1129
                     /locus_tag="ACZPB4_13525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ExbD/TolR family protein"
                     /protein_id="HIR1099269.1"
                     /translation="MALKRRTKVNEAFSMASMTDVIFLLLIFFMVTSTVVIPNAIKVT
                     LPQAQKQTAAKPLTRVTIDANLNYYVAFGKQKEVQVSFDEITPFLQDSYAKEPEMFVA
                     LYADETVPYKEIVKILNIANENKFKMVLATRPQK"
     gene            1135..1989
                     /locus_tag="ACZPB4_13530"
     CDS             1135..1989
                     /locus_tag="ACZPB4_13530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0031992 - energy transducer activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy transducer TonB family protein"
                     /protein_id="HIR1099270.1"
                     /translation="MRLNKDDIYSLIGTVAFHGVILLILWFTVLKTEVPDEDGGVLVN
                     FGNVDAAAGMFEPKYTGQEPPQETTTPPPPVPEPQVETPKQELITQDIEESVALEDAK
                     KKKEEEKRKKQEAEKKRKEEEEKERIRREEAEKKRLAEERRKKEQAISNKVAGAFGMG
                     NAEGNSQGDAESGTGNQGSPFGNSDHGANEGVGGYGSFNLNGRSIGAGGLPRPAYTIQ
                     EEGRIVINITVDPKGNVIFAEVGRGTNIDNASMRKSALDAARKAKFNSISGANNQSGT
                     ITYVYKFK"
     gene            1999..2544
                     /locus_tag="ACZPB4_13535"
     CDS             1999..2544
                     /locus_tag="ACZPB4_13535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1 family glyoxalase III"
                     /protein_id="HIR1099271.1"
                     /translation="MKKAIVFLANGFEEMEATGTVDILRRGGIDTKTVSITDDRKVIG
                     AHNMEYTADATFTEIDLSDADALILPGGMPGASNLNNSEPVKEALLQQYREGRIVAAI
                     CAAPMVLGGLGLLKGRKATCYPGFEPKLIGATVTGEAVEVDGNVVTGRGPGLVFNFGL
                     ALVSVLKGDAVAEEVAAGLLL"
     gene            complement(2672..3748)
                     /locus_tag="ACZPB4_13540"
     CDS             complement(2672..3748)
                     /locus_tag="ACZPB4_13540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HIR1099272.1"
                     /translation="MRYFFILFAIAGLLINPSAAEACTGITLKSKDSTTIVARTIEWG
                     GSNLNSQYVVVPRGYTERSYTPNGVDGMTFTARYGYVGLAVEQKEFIAEGLNEVGLSA
                     GLFYFPKYGEYEKYNAAVRDKSISDLQLVSWLLGECSNVEEVKEAVKKVHVINIDPRA
                     STVHWRFAEPSGRQLVLEIIKGELHFYENTLGVLTNSPSFEWHLTNLNNYVNLFPGTA
                     PNQQLGNIELSSFGAGSGFLGIPGDVTPPSRFVRAAFYQASAPQQETALETVFQCFQI
                     LNNFDIPVGIEFPLGQVPCDIPSATQWTSVTDMRNHVIYYRTMYNSVIRNIDLRSIDF
                     STVRYRAVSMDGTKRQAVETIKIE"
     gene            3848..4780
                     /locus_tag="ACZPB4_13545"
     CDS             3848..4780
                     /locus_tag="ACZPB4_13545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HIR1099273.1"
                     /translation="MNNNLKGFAYGIATSVTFGLIPLFTLPLMEKGMRFDSILFYRFL
                     FAAIALSGMLLAKKESFRTEMRNLPILILLGAFYTGSAMFLFWGYNFMAAGIATTLHF
                     TYPIFVTLFMLFVFKEKTSWITLLAIGLAICGVARLSIDGGEMRLNGLGVIIVLLSAV
                     AYALYIVTVNKSRVHDMPGRKLTFYVFIVSTSLFFIKAQAGTGIQPIPDLPSFINLVL
                     LAFLPTVVSNITLVQAVHHIGSTLTSVLGATEPVTAVCVGVLVFGEPFTPHLALGILL
                     IIVAVTLIILSKYIQKNLHEAKRLFKARHILRTK"
     gene            complement(4766..5656)
                     /locus_tag="ACZPB4_13550"
     CDS             complement(4766..5656)
                     /locus_tag="ACZPB4_13550"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0046428 - 1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase activity [Evidence IEA];
                     GO_process: GO:0009234 - menaquinone biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HIR1099274.1"
                     /translation="MENNRSRIQAWLEAARPKTLPASFSPVLVGCALAYRDGVFKLAP
                     AILCVLVALLAQIASNFANDYFDFKKGADKEDRLGPERAVASGWITPKAMLWGTFITL
                     GLSCLCGCFLLFFAGWELIGVGIAIAICVLAYSAGPFPLAYNGLGDVCVVLFYGIIPV
                     CFTYYVQALSFSLLSFLLSLSLGLLSANILIVNNYRDYEQDKAARKRTTIVLFGRTFG
                     LVTYLLNGILAFLITLPLLMDASPWLVCLFAAFSVLFAATWLEMKQYQGRELNRTLGH
                     TARNVFIYAVLLSVVLLFGS"
     gene            5750..6151
                     /locus_tag="ACZPB4_13555"
     CDS             5750..6151
                     /locus_tag="ACZPB4_13555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099275.1"
                     /translation="MKNFLFILGLLISFMLFAPEEGTKSMDEVMSATKEAVMKEKNTA
                     DAQRRFEVLSNELKSSNCLTPRRISQTTNNTIEIRIWKNMEKSLQDMRLRGVNQLHRV
                     SQHISTYQIINLSTLLCRMGEHVFALRKLII"
     gene            6545..6739
                     /locus_tag="ACZPB4_13560"
     CDS             6545..6739
                     /locus_tag="ACZPB4_13560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099276.1"
                     /translation="MRINKDLADAIMMVSFIVLVLVGTTTFDNEVTKNVTMGSLGVIT
                     VAMLVLRVIGSRQKEEEEAF"
     gene            complement(6886..8250)
                     /locus_tag="ACZPB4_13565"
     CDS             complement(6886..8250)
                     /locus_tag="ACZPB4_13565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HIR1099277.1"
                     /translation="MKTKPFLSFWQIWNLTFGFLGIQFGFALQNANSSRILQTYGADV
                     EQLSLFWLAAPLTGMIIQPIIGHYSDQTWCRLGRRRPFFLVGAIFTTIALILMPNAGL
                     FLSPGTETAILSPVLIGAGMLMIMDASINVTMEPFRALVGDMLPDEQHTTGFSIQTFL
                     IGIGAVVGSLLPSIMNKVFGLSNTAVAGEVADNVKFAFYAGAAILLASVLWTIFKTKE
                     YSPEEMAEFRLSGGEVIEKRRDSNGFMEIMHDIFHMPKIMLQLGLCQFFAWFALYSMW
                     VYSTPAIAEHVYGATDPASAEYAMAGDKVGELFSIYNFVAMLFALLLIPIARHLGRKM
                     THALCLCLGGAGLVSLYLLNNTGMMVFSMIGIGIAWASILAMPYAILSDSLPADKMGT
                     YMGIFNFFITIPQITNGIIHGWIVRNVYHGHAVFALLTGGVFLFFAAAAVSLVKEKKF
                     SRKV"
     gene            complement(8378..9391)
                     /locus_tag="ACZPB4_13570"
     CDS             complement(8378..9391)
                     /locus_tag="ACZPB4_13570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008771758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HIR1099278.1"
                     /translation="MKKRQITIKDIAKALHISPSTVSRSLADHPDISQETKNIVNAYA
                     REHKYKPNALALSLRTNNTKTIGVILPQIVHYFFSSVLSGIEDEAEKGGYRVIICQSN
                     ENYEKEVKGAQALLEARVCGVLASVAKTTTIYNHFQELIDSDIPMVFFDRICTGILTD
                     RVVVDDYAGVCSAVEYLIRSGCRRIAFFGSPSHLAISNNRRMGYEDALRKNGLPVDKE
                     LIKICDNYTEALRLTPELLSLPNRPDAFFAVNDETAIGVLNVVKAKGLRIPDEVSICG
                     FTNNSLAEVSDPLLTSVDQHGYELGAIAMRLLIERLNGVRDGDRIVSKIIKTNLVVRQ
                     STR"
     gene            9592..12561
                     /locus_tag="ACZPB4_13575"
     CDS             9592..12561
                     /locus_tag="ACZPB4_13575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SusC/RagA family TonB-linked outer membrane
                     protein"
                     /protein_id="HIR1099279.1"
                     /translation="MKQKMYSCDARVILSILIGLFLSCNVFAQDVTIKGNVKDAKGEP
                     IIGASILEKGTTNGTVTDFDGNFMLSAPKGSTIGISYIGYKSQDIINQGQSNLIVVLQ
                     EDTEVLDEIVVIGYGTVKKDDATGSVTAIKPDKMNRGLTTTATDMINGKIAGVNITTD
                     GGAPGSGASIRIRGGSSLSASNNPLIVIDGLPIDNDGIKGVSNPLSTINPNDIATFTV
                     LKDASATAIYGSRASNGVILITTKKGEKGSRPRVTYDGNVSISTKTKSIDVMGADEYR
                     NFVTDRFGAESSAVKLLGKENTDWQKEIFRTAVGTDHNITVSGGLNNMPYRVSVGYTN
                     QNGILKTSKFERYTGSVNLAPSFFEDHLNINFNAKGMISNNRFADTGAIGAAIAFDPT
                     QPVMNGNSKYGGYFAWENAGEFISIATKNPVAMLQQKKEEANSKNLVGNIQVDYKFHF
                     LPELRANLNLGMDMATGTQDIYYPKESPLGYVDNGKTGYETIDKYNHLLDFYLQYAKD
                     FNEKHHFDIMAGYSWQHFHRSTENAYNNLNGDNPTSYIFKTESYLISFFGRVNYSFMN
                     RYLITATLRNDGTSRFSKDNRWGLFPSVALGWKIKEEGFMKDVDAVSDLKLRLGYGIT
                     GQQDISQGDYPYMATYFAGQDGAYYQFGDQFVPIARPDGYNPNLKWEETTTWNAGFDF
                     GFLDNRITSSLDYYYRETKDLINVIDVPAGTNFKNRIVSNIGSLRNQGVEFSINAKAI
                     STPDWKWDLGFNVAWNNNEITKLTAQDDASSIVLTGTVEGGTGTMIQAQGVNHPANSF
                     YVYEQVYDQQGNPIEGLYVDRNGDGVINDEDRYFCHKPAADVTMGFTSKLVWKAWDFS
                     FSLRSNLGNYVYNNVASSNAALSEGSINNKGYLSNRPLSAFDTNFQNMNVLSDYYVQN
                     ASFLRCDNITLGYSFNKLFGVLGGRIYGTVQNPFVITKYKGLDPEVANAADKTFGIDK
                     NVYPRPLVGILGVSLNF"
     gene            12582..14129
                     /locus_tag="ACZPB4_13580"
     CDS             12582..14129
                     /locus_tag="ACZPB4_13580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RagB/SusD family nutrient uptake outer membrane
                     protein"
                     /protein_id="HIR1099280.1"
                     /translation="MNTKFFKYIIPALSLVFSVNFTSCLGDLDVTPIDPNLNVEFDQN
                     ANFAKIYAGLAITGNKGPDGQGDIADTDEGASGLMRMLFNLNELPTDEAICAWSGDVD
                     VYPLNFAKFTASNGVVLNMFNRLYIQIAQCNNFLIQTEGKDDEESLTQRAEVRFIRAL
                     DYYYLIDLYGNVPFVDENTGIGTYVPERITRANLYTYIEKELKEIEPQMKAPRANVYG
                     RADQAAVWMLLSRLYLNAEVYTGIPQWSTAAEYAKKVMDAGFSLAPNYGDNFLADNNT
                     SPEMILPICYDGVQTRSWSGLFFIASFISGDMNALDDFGTKEAWGGNRARMALVKKFA
                     SDGDLSKTADTRASFWTTDRTFEINKPTEFTEGYSVTKFKNITKSGQIGHDPNQQFPD
                     MDFPLFRLAEANLTFAEATLRAGGDKQAALSAINQLRKRAKATEITATDLTLDFVLDE
                     KAREFYFEAQRRTDLIRYNKFTSNYTWDWKGETAGGTSISSHFSLLPIPSTQLVANSN
                     LKQNPGY"
     gene            14158..>14657
                     /locus_tag="ACZPB4_13585"
     CDS             14158..>14657
                     /locus_tag="ACZPB4_13585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SusE domain-containing protein"
                     /protein_id="HIR1099281.1"
                     /translation="MNKVNILSIVFAGICAFSACTDDKDPVINDLKDSEGNNISFTLN
                     APNNSSYTLMPENASSIIDIFTCEQPDYGFAAGVTYTVQVCEGGTEFEKFESLPTTGS
                     GEKVLIKTFELNDAMNNLGMVNPTVAYNVDFRLKAFINDSVPELYSNTVNMAITPYSG
                     ARTQVY"
BASE COUNT         4448 a         3266 c         3086 g         3857 t
ORIGIN      
        1 gaagcggaaa tcaatgtgat agaccttgcc tttaagggag gttggattat ggtggtattg
       61 ttactgctct ctctgatggc tatttatatt tttgttcaac gtctgatcat cattcgccgt
      121 gcgggaaaag aagacgagac gttcatgaat cgtattaagg actatatcca tgaaggaaaa
      181 gtggactcgg ctctcaattt atgccggagc accaatacac cttccgcccg tatgatcgag
      241 aaaggcatta cccgtttggg ccgtccgatg aacgatgtgc tcgtagcgat cgagaatgtc
      301 ggaaatttgg agatcgctaa actggaaaaa ggtttcccct tgatcgcgac gaccgccgcc
      361 ggcgctccca tgcttggttt ccttgggaca gtaaccggta tggtacgtgc tttcttcgat
      421 atggcaaacg caggcaccaa tgttgatgtc tccttattat ccggtggtat ctatgaggcc
      481 ttggtgacaa ccgtgggtgg tctagtagtt ggtattatta cattgttcgc gtacaactat
      541 ctggtatctc aagtagataa cgtcgtgaac aagatggagg ctcgtacgat ggaattcatg
      601 gatttattaa atgaaccggc taattaattg aaaatggaga attgaaaatt aaatatgagc
      661 caactctcct ctatttaatt ttcaattctc cattttcaat tttcaattat aaaaaattat
      721 ggctctaaaa agaagaacaa aggtaaacga agcgttcagc atggcctcta tgaccgacgt
      781 catattcctc ttgctgatct tcttcatggt tacctctacc gtagtaatcc caaacgccat
      841 caaggttacc ttgccgcaag cgcaaaagca gacagcggcg aaacctctta cgagggtaac
      901 gatagacgca aacttgaatt actacgtggc atttggaaag caaaaagagg tacaggtctc
      961 atttgatgag atcactcctt tcttgcaaga tagttacgcg aaggaaccgg agatgttcgt
     1021 cgccttatat gccgacgaga ccgtacctta caaagagatt gtaaagatac tgaatatagc
     1081 gaacgagaat aaattcaaaa tggtgcttgc cacccgtccg cagaaataac agatatgaga
     1141 ctgaataagg atgacatata cagtttgatc ggtaccgttg cttttcacgg tgtcattcta
     1201 ctgatacttt ggtttaccgt attgaaaacc gaggtaccgg atgaagacgg gggtgtactc
     1261 gttaatttcg ggaatgtaga tgccgccgcc ggaatgttcg agcctaagta taccgggcaa
     1321 gaaccgcctc aggaaacgac cactccccct cctcccgtac cggagccgca agtggaaacg
     1381 cccaagcagg aactcatcac tcaagatatc gaggaaagcg tagcccttga ggacgctaaa
     1441 aagaagaaag aggaagagaa acgcaagaaa caagaggctg agaagaaacg gaaagaagag
     1501 gaggagaaag aacgtatccg ccgggaagaa gccgagaaga aacgtctggc cgaggaacgc
     1561 cgcaagaagg aacaagccat tagcaacaag gtggccggag cttttggtat gggaaacgcc
     1621 gagggtaaca gccaaggtga cgctgaaagc ggaaccggta accaaggaag tccgttcggt
     1681 aactctgatc atggggcgaa tgaaggcgta ggcggttacg gatcatttaa tttgaacggc
     1741 cgttccattg gtgccggagg tctccctcgt cccgcttaca cgatccaaga ggaggggcgt
     1801 attgttatca atataaccgt agatccgaaa ggcaacgtta tatttgccga ggtaggccgg
     1861 ggaactaata tcgacaatgc ctccatgcgt aaaagcgctt tggatgcagc tcgaaaggcg
     1921 aagttcaaca gtatcagcgg cgctaataac cagagtggta ctattactta cgtgtacaaa
     1981 tttaaataat tgaatcttat gaagaaagcg atcgtattct tagcgaatgg cttcgaggaa
     2041 atggaagcca cgggaaccgt agacattttg cgtcgcggag gtatagacac gaaaacagtc
     2101 tccatcacag acgaccgtaa agtgattggt gctcacaata tggaatatac ggctgacgcc
     2161 acatttaccg aaatcgatct ttcggatgct gatgccttga tcttacccgg aggcatgccc
     2221 ggagcatcca acttgaacaa ttcggaaccg gtgaaagaag ccttattaca acaataccgt
     2281 gaaggacgta tcgtagcggc tatctgcgca gctccgatgg tattaggcgg tctaggtttg
     2341 ttaaaaggtc gcaaagccac ttgttatccc gggttcgaac cgaaattgat tggtgccacg
     2401 gtaacaggcg aggctgtcga ggtagatgga aatgtggtaa ccggtagagg accgggcttg
     2461 gtattcaatt ttggcctagc tttagtatct gtactaaaag gtgacgcggt tgcggaggaa
     2521 gttgcggccg gattactatt ataagattta gatcatcagt cgaaacccaa tagaataggg
     2581 aacgtaatcc attgagttat gtttcctatt ccattgagtt ttatcaccta tcctattgac
     2641 ttacgagata tcccccaaag agctcactgc cctattctat tttgattgtt tcaaccgctt
     2701 gtcgcttcgt cccatccatg gataccgcac gataacgaac cgtggagaaa tcaatggaac
     2761 gtaaatctat attccgaata acgctattgt acatcgtacg gtaataaatc acatggtttc
     2821 gcatatccgt aaccgaagtc cattgagtag cgctcggtat atcgcaaggt acttgcccta
     2881 atgggaattc gatccctacg ggaatatcaa aattattcaa tatctggaaa cactggaaga
     2941 ccgtttccaa tgcggtttct tgttgtgggg ccgaagcttg gtaaaaagcc gcacgaacga
     3001 aacgtgacgg tggagttacg tcgcccggaa tcccaaggaa accgcttccc gcaccaaatg
     3061 aagacaactc gatatttcct aattgttgat tgggggccgt acccgggaaa agattaacat
     3121 aattattcag gttcgtcaga tgccactcga aactgggaga attagtcaga actcctaacg
     3181 tattctcata gaagtgtagc tcacccttaa taatctcaag aaccagttga cgccccgacg
     3241 gctcggcaaa ccgccaatga acggtagacg cacggggatc tatattgata acatgcactt
     3301 tcttaacagc ctctttcacc tcctctacat ttgaacattc ccccaacagc caagacacta
     3361 attgcagatc agagatactt ttatcccgaa ctgcggcatt atatttctca tattcaccgt
     3421 actttggaaa ataaaacaat ccagccgata acccaacctc attgagtcct tcagcgataa
     3481 attccttttg ctccactgcc aagcccacat atccataacg tgccgtgaaa gtcattccat
     3541 caaccccatt cggagtatac gatcgttcgg tgtatcctct tggaaccacg acatactggc
     3601 tgttcaaatt acttccaccc cattctatcg tacgtgctac aatagtcgta ctgtccttgc
     3661 tttttaaggt aataccggtg caagcctctg cagcggaagg attaataagc aagccggcaa
     3721 tcgcaaataa aataaagaaa tatctcataa acatcatttt tgataaaaac aagcgacagg
     3781 agaaggttgt tttcaagatt tcaagacttt ttcgtatgtt tgcggtcatt ttatcaaaaa
     3841 gtataatatg aataataatc taaaaggttt cgcttatgga atagcgactt ctgttacatt
     3901 cggtttaatc cctttgttta cattgcctct tatggagaag ggtatgcggt ttgattcgat
     3961 attgttctat cgtttcttat tcgcggccat cgccttatcg ggtatgcttc tagcaaaaaa
     4021 ggaatctttc agaacagaga tgcgaaacct accgatattg attttattgg gtgcttttta
     4081 tacaggctcg gcaatgttcc tgttttgggg ctataatttt atggcggcgg gaatcgccac
     4141 gactctacat ttcacctatc cgatattcgt aaccctattc atgctgtttg tattcaaaga
     4201 aaaaacatca tggattacgc tcttggcgat cgggctcgct atttgtggag tagcccgtct
     4261 atccattgat ggaggagaga tgcgattaaa cgggctaggc gtaatcatcg tattactttc
     4321 cgccgtcgct tatgccctct atatcgtcac cgtcaataaa tcgagggtac atgatatgcc
     4381 gggacgaaaa cttacgttct atgtatttat cgtcagtacc tctttatttt tcataaaagc
     4441 acaggcagga acaggaatcc aacccattcc agacctgccc tcttttatta acctcgtctt
     4501 attagccttc ttgccaaccg tagtatctaa cattacattg gtacaagccg tacaccatat
     4561 cggttccacc ctaacttccg tactgggagc aacagaaccc gtgacagccg tctgcgtagg
     4621 tgttttagtc tttggagagc ctttcacccc tcacctcgct ttaggaatct tactgattat
     4681 cgtagcggtt acattgatta tcctgtccaa atacatacag aaaaatctcc atgaggccaa
     4741 gcgattgttc aaagcacggc acatcttaag aaccaaataa caatacaact gaaagcaaca
     4801 cggcatagat aaatacattc cgtgccgtat gccctaaagt tctattaagc tcacggcctt
     4861 gatactgttt catctccagc catgtggcgg caaacagcac gctaaaagcc gcgaataaac
     4921 aaacaagcca aggtgaggca tccatcaata aaggcagcgt gatcaaaaaa gccaatatac
     4981 cgttcagcaa ataagttacc aacccgaacg tacgcccgaa tagcacaatc gtagtccgtt
     5041 tacgagccgc cttatcttgc tcataatccc ggtaattatt cacgatcaaa atattagcgg
     5101 acaacagccc caatgacaac gaaagcaaga atgacaataa ggaaaacgat aatgcttgta
     5161 cataatacgt aaaacaaacc ggaataatcc cataaaacaa tacgacacac acatccccca
     5221 gcccgttata agccaaagga aatggccctg ctgaataagc caagacacaa atcgcaatag
     5281 caattcctac accgatgagc tcccagccgg caaagaacaa caagaaacag ccacatagac
     5341 aagaaagccc caacgtgata aaagtccccc atagcattgc cttaggagtt atccaaccgg
     5401 aagccaccgc tcgctccggg cctaaccggt cctccttatc cgcccccttc ttaaaatcaa
     5461 aataatcatt ggcaaaatta ctggctatct gggcaagtaa agccaccaaa acacaaagga
     5521 tcgccggagc caatttaaat actccatccc tgtaagccag cgcacaccca actaataccg
     5581 gactaaatga tgccggcaac gttttcggac gtgccgcctc taaccaagct tgaattctcg
     5641 atctgttatt ctccattcta ttgttttatt cttaaaataa ctacaaaaat aaaaaacaaa
     5701 taacatatac tgttgttatt atctaaagaa atacttgtat atttgcgcca tgaagaattt
     5761 tctattcata ttaggtctgt tgattagctt catgctgttt gctcccgaag aaggaacaaa
     5821 gagtatggat gaggttatgt ctgcgactaa agaggccgtt atgaaagaaa aaaacacggc
     5881 ggatgcccaa cgtcgtttcg aagtattaag taacgagctg aaaagcagca actgcttaac
     5941 tccccgcagg atttcacaaa cgacaaacaa cactatcgaa atacggatat ggaaaaatat
     6001 ggagaaatcc cttcaagaca tgcgtttgag aggagtaaat caacttcata gagtatctca
     6061 acatatatcc acttatcaga tcataaattt atccacactt ctgtgtcgta tgggagagca
     6121 tgtctttgcc ctacgaaaac tcattattta gtttttaatt gtttcatatt tgtatctttc
     6181 ggtaagtcat tgatatgtct tatcggcagg aatattgcat ttattaaatc aatatttccg
     6241 gggagttatt gcccatttac attattataa acaattaaaa attacaatta tgacaactaa
     6301 taaatcaggt aaaatacgta tatatcttta tgttcttcta acaatcgcag gttgtgtatt
     6361 cgcatgcagt tctatcatcc ctaacgacta tattaaatta gtagtagtta tgggcactct
     6421 atgtgttggt ctatatggca taatgaaagg actgagtagt accgggacgt catcggaaga
     6481 ggaagtcttg gaaaaagaat aataaaatac aacaattatc gaatcctaaa aaaataagaa
     6541 gatcatgaga ataaataaag atttggctga tgcaatcatg atggtttcat ttatcgtatt
     6601 ggtattagtc ggaactacaa catttgacaa tgaggttact aaaaacgtaa ccatgggatc
     6661 cctcggtgtg attacggtag cgatgttagt tcttcgcgtc ataggatcac gccaaaagga
     6721 agaggaagaa gccttttagt agttagtcca ttggtttcct gttgttgtcc cggggtgacc
     6781 cgggattatc tgagatacgt ttttctacct acattataat aacttgctgt ttgacttggg
     6841 tatagcgttt ttacgcttga caacaggaaa ccggacttat ataccttaca cttttctact
     6901 gaactttttc tctttgacaa gactaactgc ggcggcggca aaaaacaaga aaacacctcc
     6961 cgttaacaaa gcgaacacag catgcccatg ataaacatta cgtacaatcc atccatgaat
     7021 gattccattc gtgatctgag gtatcgttat aaagaaatta aatataccca tataagtacc
     7081 catcttatca gcgggaagac tatcggaaag aatagcataa ggcatcgcca atatacttgc
     7141 ccacgctata ccgatgccaa tcatagaaaa gaccatcatt cctgtgttat tcaacaaata
     7201 gagagaaacc aaccctgccc ctcctaggca taaacagagg gcatgagtca ttttccgacc
     7261 taaatgacgg gcaatcggga tcaataataa agcgaataac atcgccacaa aattatagat
     7321 actgaataac tcacctacct tatcgccagc catcgcatat tcggcggaag caggatctgt
     7381 tgccccatat acatgttcag cgatagcagg cgtagaataa acccacatgg aatacaaggc
     7441 aaaccaagcg aaaaactggc ataaacctaa ctgtaacatt attttaggca tatgaaagat
     7501 atcatgcatg atctccataa aaccattgct atcccgcctt ttttcaatga cctcaccacc
     7561 ggaaagccga aactcagcca tctcttctgg ggaatattcc tttgtcttaa aaattgtcca
     7621 taatacgctc gctaataaaa tcgccgcacc ggcataaaag gcgaatttaa cattatcggc
     7681 aacctcacca gcaaccgccg tattagataa accaaacacc ttattcataa tactcggcaa
     7741 caaggaacca acgacagcac cgatgccgat caagaaagtc tggatcgaga agccagtcgt
     7801 atgctgctca tcgggtagca tatcccctac caaggcacgg aaaggctcca tcgttacatt
     7861 gatggaagca tccatgatca tcaacatacc cgcaccaatc aatacgggag ataaaatagc
     7921 cgtctctgta ccgggtgaca agaacaatcc cgcattcggc atcaatatca aggcaatcgt
     7981 cgtaaagata gctcctacca gaaaaaacgg acgccgacgt cctaaacggc accatgtttg
     8041 gtcggaataa tgaccaatga taggttgtat gatcatacct gtcagcggag ccgctaacca
     8101 aaataaggat agttgctcta catccgctcc ataggtttga agtattctac ttgaatttgc
     8161 gttctgaagg gcgaaaccga attgaatgcc caagaaaccg aaagttagat tccaaatttg
     8221 ccaaaaactc aaaaatggtt ttgttttcat gagaattatg ttttttaagg tatttatttg
     8281 tttggtgaca aacatacgga attattccga aacaggacgt cgtccctatt caaattcatg
     8341 caaagaagta gagcaaacgt tttcggaagc tactttttta acgggtagac tgtctcacca
     8401 ccagatttgt cttgataatc ttgctcacga tacgatcccc gtcacgcaca ccattcaaac
     8461 gttctatcag taaacgcata gcgatagctc ccaactcata accatgttga tccacggagg
     8521 tcagcagggg atcactaact tccgctaagc tattattcgt aaacccacaa atcgaaacct
     8581 catcgggtat cctcaatccc ttggccttga caacattcag cacccctata gcagtctcat
     8641 catttacggc gaagaacgca tccggacgat tgggcaacga caataattcc ggggtcaacc
     8701 gaagcgcctc ggtataatta tcacaaatct taattaactc tttatctacc ggtaatccat
     8761 ttttacgcaa agcatcctca tatcccatcc tacgattatt agagatcgct aaatgagaag
     8821 gagatccgaa aaaggcgatt cgccggcaac cgctacgaat caagtattca acagcggaac
     8881 aaaccccggc ataatcatca acgaccaccc ggtctgtcaa gatccccgtg catatacgat
     8941 caaaaaacac cataggtata tcgctatcga ttagttcttg gaaatgattg tagatcgtcg
     9001 ttgttttagc gacagaagcc aagacaccgc aaacacgtgc ttccaataaa gcttgcgcac
     9061 cttttacttc tttctcataa ttctcattac tttgacaaat aataacacga taccctccct
     9121 tttccgcctc atcctctata ccggataaaa cagaagaaaa gaaataatgt acgatctgcg
     9181 gtaaaataac accgattgtt ttcgtattat ttgtccgtaa actcaaggct aaggcattgg
     9241 gcttatattt atgttcacga gcgtaagcat tcactatatt cttggtttct tggctgatat
     9301 ccggatgatc agccaaggaa cgagagactg ttgacgggga aatatgcaag gctttcgcta
     9361 tatcctttat cgtgatttga cgctttttca tggttctctt ttttataaaa tcaaagatat
     9421 gtatttaggt catacaatgc aaacgtttgc gagaacgttt gcgtaaattt ataggggtat
     9481 cgacaaacat tttaacaaca tgagaggttt gataaacata catttgcatt cacatactat
     9541 ggctaaaatt caataaatat aatagagtat taatcttaaa ctgtctaatg catgaaacaa
     9601 aaaatgtatt cttgcgacgc aagagtaatc ttatctatct tgataggatt gtttctctcc
     9661 tgcaatgttt tcgcacaaga cgtcacgatc aaaggcaacg tgaaagatgc gaaaggtgaa
     9721 cccatcattg gggctagtat ccttgaaaaa ggaactacga atggaactgt taccgatttc
     9781 gacggtaact ttatgctttc ggcgcctaaa ggaagtacga tcggtatttc ttacataggc
     9841 tacaaatcac aagacattat caaccaagga caaagtaatt taattgtcgt attacaagaa
     9901 gatacggaag tattggacga gattgtcgta atcggttatg gtacggtgaa gaaagatgac
     9961 gctaccggtt ccgtgacggc cattaagcca gataagatga accggggttt gaccaccacc
    10021 gcaaccgata tgatcaacgg taaaatcgcc ggtgtaaata tcacgactga cggtggagct
    10081 ccgggttcgg gagccagtat ccgcatccgt ggtggttctt ccttatcggc cagcaacaac
    10141 ccgctgatcg ttatcgatgg acttccgatc gacaatgacg gtatcaaagg ggtatccaac
    10201 ccgttgagta cgatcaaccc gaacgatatc gcaacattca ccgtattaaa agacgcatcc
    10261 gccacagcga tctatggttc gcgtgcctct aacggtgtga ttcttatcac cactaagaaa
    10321 ggtgagaaag gctcccgccc acgggttacg tacgatggaa acgtttctat cagcacgaag
    10381 accaaatcaa tcgatgttat gggagctgac gaatatcgta atttcgtaac ggatcgtttt
    10441 ggggcggaat caagcgccgt taagttatta ggaaaagaaa atacggattg gcagaaagag
    10501 atcttccgta cagcagtggg aaccgatcat aatatcacgg tgtccggagg cttgaataat
    10561 atgccttatc gtgtatccgt cggatataca aaccaaaatg gtatattgaa aacctctaag
    10621 ttcgaacgtt atactggatc tgtaaaccta gctcccagtt tcttcgaaga tcatttaaat
    10681 attaacttca acgccaaggg aatgatctca aataatcgtt tcgccgatac gggagctatc
    10741 ggagcggcaa tcgcattcga cccgactcaa ccagtcatga acggcaacag taaatacgga
    10801 ggttatttcg cttgggaaaa tgccggtgaa tttatctcaa tcgctacaaa aaacccggta
    10861 gcgatgcttc aacagaaaaa agaagaggct aattctaaaa acttggtcgg taatatccaa
    10921 gttgattata aattccattt ccttcccgaa ttacgtgcaa acttgaattt aggtatggat
    10981 atggctaccg gtacgcaaga catttactat ccgaaagaat ctccattagg ttacgtggat
    11041 aacggcaaaa caggttatga gacaatcgac aaatacaatc acctattgga tttttatttg
    11101 caatacgcta aggatttcaa tgaaaagcat cattttgata tcatggctgg ttactcttgg
    11161 caacatttcc atcgttccac agagaacgca tacaataact tgaacggaga taacccgact
    11221 tcttatattt tcaagacaga aagttatttg atctctttct tcggacgtgt caattattca
    11281 ttcatgaatc gctatcttat caccgctacc ttacgtaacg atggcacttc ccgcttctct
    11341 aaagacaacc gttggggatt gttcccttcc gtggctttag gatggaagat caaggaagag
    11401 ggctttatga aagacgtgga cgctgtatcg gatttaaaac tacgcttggg ttatggtatt
    11461 actggtcaac aggatatctc gcaaggagac tacccgtata tggcgactta tttcgcagga
    11521 caagacggag cctactatca atttggcgac caatttgttc ctatcgcccg tcccgacggt
    11581 tacaacccga acttgaaatg ggaggagact actacttgga acgccggatt cgacttcgga
    11641 ttcttagata accgtatcac ttcatccttg gattattatt acagggaaac taaggacttg
    11701 atcaatgtga tcgacgtacc tgccggaaca aacttcaaga accgtatcgt cagcaatatc
    11761 ggttctttga gaaatcaagg tgttgagttc tccatcaacg ctaaagcgat ctcaacccct
    11821 gattggaaat gggatctagg ctttaatgtc gcttggaaca acaacgagat taccaagcta
    11881 accgcacagg atgacgcctc atccatcgta ttgacaggaa ccgtagaagg tggtaccggg
    11941 accatgatac aggcacaagg cgtgaatcac ccggcgaact cattctatgt atacgagcag
    12001 gtatatgatc aacagggaaa tccgatcgaa ggattatacg tggaccgcaa cggagatggc
    12061 gtgatcaatg acgaggaccg ttatttctgc cataaaccgg cggccgatgt aacgatgggc
    12121 tttacttcta aattggtatg gaaagcatgg gatttcagtt tctcacttcg ttccaacctc
    12181 gggaactatg tatataataa tgtagcctca tccaatgcgg cattaagtga aggtagtatt
    12241 aacaataaag gctatctatc caaccgtccg ctatccgctt tcgatacgaa tttccagaac
    12301 atgaacgtat tgtccgatta ttatgtacaa aacgcatcct tcttacgctg cgataatatc
    12361 acgttgggtt actctttcaa caaattattc ggcgtattgg gcggacgtat ctacggaacc
    12421 gtacagaatc cttttgttat cacgaaatat aaaggattgg atccggaggt agcgaacgca
    12481 gctgataaga ccttcggtat cgataagaac gtatatcctc gcccattggt aggtatactc
    12541 ggtgtaagtc ttaacttcta attttaaatc aggatatcta tatgaatacg aaattcttta
    12601 aatatataat accggcttta tcgctggttt tcagcgtaaa cttcacctct tgcctaggtg
    12661 atctcgatgt tacgcctatc gatccgaacc taaacgtaga gttcgatcag aacgccaatt
    12721 tcgccaagat ctatgcggga ttagccatca caggaaataa aggtcccgac ggacaaggag
    12781 atatcgccga cacggatgag ggagcgtcgg gtttgatgcg tatgctattc aacctaaatg
    12841 agcttcctac ggacgaggcg atttgcgctt ggtctggcga cgtggatgta tatcccttga
    12901 acttcgctaa gtttaccgcc tcgaacggtg tggtattgaa tatgttcaac cgtctgtaca
    12961 tccaaatcgc tcagtgtaat aacttcttaa tacagacaga gggcaaggat gacgaggaaa
    13021 gtcttacaca gcgtgctgaa gttcgtttta tccgtgcctt ggattattat tatttgattg
    13081 atttatatgg caatgttccg ttcgttgatg agaacacggg tatcggtacc tatgtccccg
    13141 aacggattac ccgggcgaat ctctatacct atatagagaa agagttgaaa gaaatcgagc
    13201 cacaaatgaa ggctccccgt gcaaatgtat atggacgtgc cgatcaagcc gccgtatgga
    13261 tgctactttc ccgcttatat ctgaacgcag aagtatatac aggtatccct caatggtcta
    13321 ccgccgctga atacgcaaag aaagtcatgg acgccggttt ctctctggct cctaattatg
    13381 gagataattt ccttgcagat aacaacacct ctcccgagat gatcctgccg atttgttatg
    13441 atggcgtaca gactcgctct tggtccggat tgttctttat cgccagcttt atcagtggtg
    13501 acatgaacgc actggatgat ttcgggacta aagaagcatg gggtggtaac cgtgcccgca
    13561 tggcattggt gaaaaagttc gcttctgatg gagacttatc gaaaacagct gatacacgtg
    13621 cctctttctg gactacagac cgtacattcg agatcaataa gccgaccgag tttacagaag
    13681 gttattctgt aactaaattc aagaatatca cgaaatccgg acaaatcggt cacgatccga
    13741 atcagcagtt cccggatatg gatttcccat tgttccgttt agccgaggct aatctgacct
    13801 tcgccgaagc cacattacgg gcaggaggcg ataaacaagc cgctttaagc gctattaacc
    13861 aactacggaa aagagcgaaa gccacggaaa ttacggcaac cgatcttact ttggattttg
    13921 tgcttgatga gaaggcccgt gagttctatt ttgaggcgca acgccgtacg gatttgatcc
    13981 gctacaataa gttcacctcc aattatactt gggattggaa aggcgagaca gcgggaggta
    14041 cttcaatctc cagtcacttc tcattgttac cgattccttc gacccaactc gtggcaaaca
    14101 gtaacttgaa acaaaatccg ggttattaat cgtaaaacct attaataagt aacaattatg
    14161 aataaagtca atatattatc catcgtgttt gcgggcatct gtgctttttc tgcctgcacg
    14221 gacgataaag atccggttat caatgaccta aaggactcag aaggtaataa tatatctttt
    14281 accctcaatg ctccgaataa tagctcatat actttaatgc cggaaaatgc cagtagtatc
    14341 atcgatattt ttacctgtga acaaccggat tacggttttg cggcaggtgt aacgtatacc
    14401 gtacaagtct gtgaaggagg aactgaattc gagaaattcg agtcgctgcc gactaccggt
    14461 tccggcgaaa aagtcttgat caagacattc gagctgaatg atgccatgaa caatttggga
    14521 atggttaatc ctaccgtagc ttataatgtg gacttccgtc ttaaagcatt tattaacgac
    14581 agtgttcccg aactttattc gaacacggta aacatggcga tcactccata tagtggcgcc
    14641 cgtacccaag tttattt
//
LOCUS       DBMDTB010000097        14335 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_1325_length_14335_cov_10.439160, whole genome shotgun
            sequence.
ACCESSION   DBMDTB010000097 DBMDTB010000000
VERSION     DBMDTB010000097.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 14335)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 14335)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14335
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1325_length_14335_cov_10.439160"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            425..2779
                     /locus_tag="ACZPB4_13590"
     CDS             425..2779
                     /locus_tag="ACZPB4_13590"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HIR1099282.1"
                     /translation="MKKKSVWALALAAMLMWVGKPAVAAVNEAFDPVEYVNPLMGTQS
                     SFELSTGNTYPAIARPWGMNFWTPQTGKMGDGWQYVYTANKIRGFKQTHQPSPWINDY
                     GQFAIMPVVGKPEFDQDKRASWFSHKGEIAKAYYYKVYLAEHDVVTELTPTDRAAMFR
                     FTFPENEHSYIVVDALDKGSYIKVIPEENKIIGYSTKNSGGVPDNFKNYFVIEFDKPF
                     TYEATFADASLKEGAKEQTSDHVGAVIGFKTKKGEIVHAKVASSFISFDQAAINMKEL
                     GNDNFDTLVQKGKDVWNEHLSKIEVEGGDLDQYRTFYSCFYRSLLFPRKFYEINAQGE
                     VVHYSPYNGEVLPGYMFTDTGFWDTFRSLFPFLNLMFPSVNKEMQEGLINTYKESGFF
                     PEWASPGHRGCMVGNNSASILVDAYMKGVKVDDLETLYKGLIHGTENVHPKVSSTGRL
                     GHEYYNKLGYVPYDVKINENAARTLEYAYNDWCIWQIAKQLGRPKKELELYARRALNY
                     KNLYDKETKLMRGKNENGEFMAPFSPLKWGDAFTEGNSWHYSWSVFHDPQGLIDLMGG
                     KDSFVMMLDSVFAVPPLFDDSYYGGVIHEIREMTVMNMGNYAHGNQPIQHMIYLYNYA
                     GQPWKAQYWLRQVMNKMYTPGPDGYCGDEDNGQTSAWYVFSALGFYPVAPGTTQYVLG
                     APLFKKATIHFENGNNLVINAPNNSDKNIYIESMTFNGKNYTKNYLDHNDLFKGGVID
                     FKMGDKPNMNRGINPEDMPYSFSVNEEGINKLSPISVKPSKKKK"
     gene            2789..5059
                     /locus_tag="ACZPB4_13595"
     CDS             2789..5059
                     /locus_tag="ACZPB4_13595"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HIR1099283.1"
                     /translation="MNFIHKPLMSGIAICLTFFAYSCATPEKTENKTDFTAYVDPYIG
                     SGEHGHVFVGANVPFGAVQVGPQNIFKGWDWCSGYHYSDSIIIGFSHTHLSGTGCSDL
                     GDILLMPYTGEVRTARGEQDNIEGAASSYYKHANEAVAPGYYSLLMDNGVKAELTATE
                     RVALHRYTYPSGSEHRLLINLKEGIGDKAYDTYLKKIDEYTIEGYRFSKGWSPRHKVF
                     FTLKCDQPIESLAVFNDDEAAGNDELTGESVKGVITFKGDAPTALVKVAISSVSCENA
                     LANLRTELSHWDFDEVRNEAIDKWNDQLSCISIDTKDERAKKVFYTAMYHAFIAPTLY
                     CDANGDFRGHDDKVYTNNTWKNYSTFSLWDTYRTLHPLFTIIKPQYVSDLVNSMLSIY
                     DQQEKLPIWPLIGGETDQMPGYSAVPIIADAYLKGFTGFDADRAYRYMVASSVYEKQN
                     GVPYVLEKGYIPCDKVREATSIAMEYAADDWGIALMAKKMGKTEDYQNYLKRGKYYTQ
                     YFDKDINFIRPKMNDGSWRTPYDPIQSIHSVGDFCEGNGWHYTFFVPQHPEGLIELMG
                     GDAPFISKLDSLFLVEGELGENASPDISGLIGMYAHGNEPSHHVTYLYPYAGEQWKTA
                     EKVRYIQDVFYTDQPEGIIGNEDCGQMSAWHIMSALGFYQVNPSNGVFVFGSPLFDKA
                     SVHLPEGKTFEVVAQNNSKENVYIQSVLLNGKPYNNSYILYDDIVKGGNLTFVMGSTP
                     NKEFGAAPENRPKTAE"
     gene            5178..7454
                     /locus_tag="ACZPB4_13600"
     CDS             5178..7454
                     /locus_tag="ACZPB4_13600"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HIR1099284.1"
                     /translation="MKTKLKTSMALLASAFLWVSCAGGGGTSPSAMDPVDYVNPYMGN
                     ISHLLVPTFPTVHLPNSMLRVYPERADFTGDRLGGLPIIVTNHRERSAFNLCPYQGDE
                     SGLRPVIAYSYDREKILPYRYQVYLDNEEIDVDFAPSHQSAVYSLTFEKEGPAYLVFN
                     SRNGQLQVNGNAVSGYQYIDKKTKVFLYAETNQKPVKAGVLSNGSVNYNETSVEGINA
                     AIALSFGEDVKKLGVRYGISFISEEQAKKNLEREIAAYDVDVVAKIARNDWNDALGKI
                     QVQGGTKDEKTVFYTSLYRCYERPINLSEDGHYYSAFDGKIHEDGGRSFYTDDWIWDT
                     YRATHPLRVLIDNERENDIINSYLLMAEQMGTDWMPTFPEVTGDTRRMNSNHAVATVI
                     DAYRKGLRGFELEKAYIACKKGIEEKTLIPWSAAPAGWLDDFYKEHGYIPALRPGEKE
                     TVPNVSIWEKRQPIAVTLGTSYDEWCLSQIAQELGKKDEADYYLRRSYNYRNVFNPET
                     GFFHPKDKDSKFIYPLDYRYDGGLGARDYYDENNGYIYRWDVQHNIGDLISLIGGNEA
                     FTSALDSMFNTPLGMSKWQFYSTLPDHTGNVGMFSMANEPSLHIPYLYNYAGKPWMTQ
                     KRIRTLLNQWFRNDLMGVPGDEDGGGMSAFVVFSQMGFYPVTPGSPTYNIGSPMFTDV
                     KVDMGNGNTFEIRANNASDENKYVQSAKLNGVTLNQPWFNHSDIAAGGLLELEMGPKA
                     NKEWGLGTPPPSAAPMPK"
     gene            complement(7490..10030)
                     /locus_tag="ACZPB4_13605"
     CDS             complement(7490..10030)
                     /locus_tag="ACZPB4_13605"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hybrid sensor histidine kinase/response
                     regulator"
                     /protein_id="HIR1099285.1"
                     /translation="MNNIHSNTTFLNEAIDKKTDVEDEKTDLILANMIDLRKTMSDVL
                     SLLLGAKKNSVIDQALFRILQFFDVDRVYIGTFDEQTHTVDFTNEVTCDGIISMREDL
                     LRQLPQDEIPWWYDSIKKGMDIVIHDVSKMPEEAKSEQHLLILQEVSSLLVIPIFKQG
                     KPSGFIGFDSVKKKRNWSALDIENLHMLADILSIAIERGEVQGLVEHTAMQVMKSETK
                     FKIIFDKMPWGAELYDENGVLVDINQADLDIFGVTREQAVGLNMFENPNIPKYVNQSL
                     KNGKDIFFPLNYDFKVASQNGYYDSHHDSKTKHLLVKGVTLKDSLDNIFGYIYIVFDD
                     TENHIKREQIENSLARLKVSVDTGDSILWEYDVENDKLTVDFGLNEDINNNEGLKAIH
                     DYNFKNQEDYKSSIHPDDFDRVYNKQFKPLLQGKINNFVAAYRRILNGKTFWFNSNVR
                     SYKFNDDGTPNRIVSYTSNITQQREKEIELIKVKEADKLKSAFLANMSHEIRTPLNAI
                     VGFSNIIAEIDDEVERQSYLDIIHKNNDLLLQLIDDILDFSKIEAGTMDYHFEEVDIK
                     DICGEIALADSIKMPSDVVLIFDLGSPSVIVKTDERRVMQVISNFVNNAIKFTTKGSI
                     TIYYEIEGDFIRVCVKDTGIGISAENQRRIFERFIKVDTFQQGTGLGLTISRTIIEAL
                     GGKIGVDSEEGVGSTFWFTLPLDTKRTDIELSPDIPVQSEETPRSDRHHSILIAEDVY
                     ENYFLLETLFGKQYQLYHALNGQEAIDMFETYHPDLILMDIKMPVMDGFEATRRIRTL
                     SKTIPIIALTAFAFEREKEIAKQCEFTDYVVKPIDIKELKKLIVKVLA"
     gene            10176..10823
                     /locus_tag="ACZPB4_13610"
     CDS             10176..10823
                     /locus_tag="ACZPB4_13610"
                     /EC_number="2.7.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_function: GO:0050145 - nucleoside monophosphate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidylate kinase-like family protein"
                     /protein_id="HIR1099286.1"
                     /translation="MDNKIILTIGRQFGSGGREIGQRLAKELGIGYYDKELITVAARE
                     SGLCEDVFEKADERASSGLSYAFTMGYSSFMGGMFTPYNDILSNDGLFKIQSDAIRKL
                     AETESCVLVGRCADYILRDNPACLSFFIHSSVESRVQKTVERHGVTVEEAKNMMEKTD
                     KSRAAYYNYYTNKTWGMASSYNFSIDVSVLGIDETVEFMKSFIERRLNKRPPHFG"
     gene            10882..11196
                     /locus_tag="ACZPB4_13615"
     CDS             10882..11196
                     /locus_tag="ACZPB4_13615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucosidase"
                     /protein_id="HIR1099287.1"
                     /translation="MRKPFITVRLTHGMLGALLVSTCACSGTKWTEVEKDSIRIVTQQ
                     EGAVLGYSANSGVRLLTVDGYAFKDLNRNGRLDPYEDWRLTPEERAVDLAGQYLQRKS
                     PD"
     gene            11196..11489
                     /locus_tag="ACZPB4_13620"
     CDS             11196..11489
                     /locus_tag="ACZPB4_13620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucosidase"
                     /protein_id="HIR1099288.1"
                     /translation="MLYSAHQSIPGASKGFGTSTYNGKSFDESGAQPSDLSDAQRKFL
                     TEDNVRHVLVTRVQSPKVAARWNNNAQALVEGIGHGILRSLIIPMRRISPSSL"
     gene            11486..12043
                     /locus_tag="ACZPB4_13625"
     CDS             11486..12043
                     /locus_tag="ACZPB4_13625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 3 C-terminal
                     domain-containing protein"
                     /protein_id="HIR1099289.1"
                     /translation="MTSPNSGTGYDKSDCEKGGNGYMPISLQYNDYTATYARNPSLAG
                     GDPFENFTNRSYKGKSVKTANKQDMLSVLETKAKMKGKPVIVSLEMDKPTIMSEFEGS
                     ADAILVNFGVQNQAVLDIISGKAEPSALLPLQMPADMRIVEEQFEDVPRDMKCYTDSE
                     GHLYDFAFCMNWKGVIDYERVTKYK"
     gene            12129..12533
                     /locus_tag="ACZPB4_13630"
     CDS             12129..12533
                     /locus_tag="ACZPB4_13630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099290.1"
                     /translation="MKIMTLQGTDKLLYELVAPLVMNPAILRQNNNYPFKTSRSHVWY
                     IAFHETAVVGFMPVKKGHLYYSIDNYFVSGDDPSVLSELLEEVIKDFSSQASLMAVVH
                     KRHVKVFSQKKFQTCVEWKNYDKMHYLPEVES"
     gene            12530..13831
                     /locus_tag="ACZPB4_13635"
     CDS             12530..13831
                     /locus_tag="ACZPB4_13635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3440 domain-containing protein"
                     /protein_id="HIR1099291.1"
                     /translation="MMRRMDVYEATEKRLKIIFDYFDYVYVSFSGGKDSGVLLNLCVD
                     YIRRYAPGRKLGVFHMDYEVQYSQTTEYVEKVYAANSDILDIYHCCVPFKVQTCTSMF
                     QQYWRPWSEEYRDIWVREMPHSCLRAKDFDFFKEDMWDYDFQNMFPFWLYQRKMGRRI
                     CCLVGIRTQESFNRWRAIHSDKNYRKLANYKWTRRMNYSIYNAYPIYDWKTQDIWIAN
                     GKFGWTYNHLYDLYYQAGVPLSRQRVASPFISQAISTLFIYKVVDPDMWGRMVGRVNG
                     VGFAGIYGNTSAMGWRAIKCPAGFSWEKYMYFLLNTLPEETRENYLNKLRVSRKFWRE
                     KGGCLSEETIAKLRAANIPIIVEECTAYHTDKKPVRMEYIDDINIPEFKEIPTYKRMC
                     VCILKNDHTCKYMGFSQTKRERDMRKEVMDKYNFYKHGKLC"
     gene            13815..>14335
                     /locus_tag="ACZPB4_13640"
     CDS             13815..>14335
                     /locus_tag="ACZPB4_13640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005798034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0071453 - cellular response to oxygen
                     levels [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IbrB-like domain-containing protein"
                     /protein_id="HIR1099292.1"
                     /translation="MGNFVSPAYGVRAVPIEKIVANSYNPNIMAPPEMRLLELSIWED
                     GYTMPCVCYYLEEDDLYEIVDGYHRYLVMKQSQRIYDREKGMLPVTVIEKDISNRMAS
                     TIRHNRARGMHNLELMTEIVTELVKSGMSDKWIMRNIGMDKNELLRFKQISGLAELFR
                     DKEFGWSDDWSEE"
BASE COUNT         3901 a         2771 c         3503 g         4160 t
ORIGIN      
        1 caaacagaac gctgaggctt tagctatccc ttgaagggat aatagcttag attcattctt
       61 tgtcattttg ctcttgtttt aaattaagtt tagattgatt acatttatat gtaatattat
      121 attgtagaat agacatagtt cgtacggaac tcgcatgtga tatttaatct ttttcgggaa
      181 tgataaaagt gcgatgaata gggcatgatc tagctcattg gatttctttt ttctaattct
      241 ttttgttaga tttgcaccta gattcgtata atgccagaaa ttcataagaa agaaagggat
      301 atttctaaat aaatgacacg agaatcactt tctattcatg ttaattaaat ggatatttgt
      361 agtccaacta tgaatataaa acacaaaaac ggataaatta tattattaat taaatagcta
      421 tatcatgaag aaaaaaagcg tttgggcttt agctttagcg gcgatgttga tgtgggtggg
      481 aaaacctgcg gtagcggctg tgaatgaggc ttttgatcca gtagagtatg taaacccgct
      541 aatgggtacg caatcttctt ttgagttgtc tacaggaaat acctatccgg cgatcgctcg
      601 tccgtggggt atgaatttct ggactcctca gacaggaaag atgggagatg gatggcagta
      661 tgtatatacg gctaacaaga tccgtggctt taaacagacc catcagccaa gcccgtggat
      721 caatgattac ggacaatttg caatcatgcc ggtggttggt aaaccggaat tcgaccaaga
      781 taaacgtgcg agctggttct cgcataaagg agagatcgcc aaggcttatt actataaggt
      841 atatctggcg gagcatgacg tggtaacgga attaacgccg acagatcgtg ccgctatgtt
      901 ccgtttcact ttcccggaaa acgagcattc ttatatcgtg gtggatgcct tggataaggg
      961 gtcttatatc aaggtgattc cggaggagaa taagatcatc ggttattcaa cgaagaatag
     1021 cggtggggtt cccgataatt tcaagaatta ttttgtgatc gagtttgata agcctttcac
     1081 atacgaggct acatttgccg acgcttcttt gaaagagggt gcgaaggagc aaacgagtga
     1141 ccatgtagga gccgtaatcg gtttcaagac gaagaagggt gaaatcgttc atgcgaaggt
     1201 ggcttcctct tttattagct tcgatcaggc cgctatcaac atgaaggaat taggtaacga
     1261 taactttgat accttggttc agaaaggtaa ggatgtttgg aatgagcatt tgagcaagat
     1321 cgaggttgag ggtggagatt tggatcaata tcgtacgttc tattcttgtt tctatcgttc
     1381 attgttgttc cctcgtaagt tctatgagat caacgctcag ggcgaggtgg tacactacag
     1441 tccgtataat ggtgaggtat taccgggtta tatgtttacc gataccggat tctgggatac
     1501 gttccgtagt ttgttcccat tcttgaactt gatgttcccg tcggtaaaca aggagatgca
     1561 agagggcttg atcaatacat ataaggaaag cggcttcttc ccggaatggg caagtccggg
     1621 tcaccgtggt tgcatggtcg gtaataactc ggcgtctatc ttggtagacg cttatatgaa
     1681 gggtgtgaag gttgacgatt tggagacttt atataaaggt ttgatccatg gtacggaaaa
     1741 cgttcacccg aaggtctctt ctacaggacg tctgggtcat gaatattata ataagttagg
     1801 atatgttcct tacgacgtga agatcaacga gaacgccgcc cgtacattgg aatatgctta
     1861 caatgactgg tgtatctggc agatcgctaa acaactaggc cgtccgaaaa aggaattgga
     1921 attatatgcc cgtcgtgcgt tgaactataa gaacctgtac gacaaggaaa ccaagttgat
     1981 gcgtggcaag aatgagaatg gcgagtttat ggctccgttc tctccgctga aatggggtga
     2041 cgctttcacg gaaggtaata gctggcatta ttcatggtct gtattccacg atcctcaggg
     2101 attgatcgac ttgatgggcg gtaaggattc atttgtgatg atgcttgact ccgtatttgc
     2161 tgtaccgcct ttgttcgatg atagctacta cggtggtgtg atccacgaga tccgtgagat
     2221 gaccgtgatg aatatgggta actacgctca tggtaaccag ccgatccagc atatgattta
     2281 tttatataac tatgcgggtc aaccttggaa ggctcaatat tggttacgtc aagtaatgaa
     2341 taagatgtat actccgggtc cggatggtta ttgcggtgat gaggataatg gccagacttc
     2401 cgcttggtat gtattctcag cgttaggatt ctatccggta gctccgggta cgacccaata
     2461 tgtgttgggc gctccgctgt tcaagaaggc tacgatccat tttgagaatg gaaacaactt
     2521 ggtgatcaat gccccgaaca acagcgataa gaatatctat atcgaatcca tgacgttcaa
     2581 cggcaagaac tacactaaga attatctgga tcataacgat ttgtttaagg gtggcgtgat
     2641 cgacttcaag atgggtgaca agccgaatat gaatcgtggt attaatccgg aggatatgcc
     2701 ttactcattc tccgtaaacg aggaagggat caataaactt tcccctattt ctgtaaaacc
     2761 tagtaaaaag aagaaataag caattaagat gaatttcatt cataaaccat taatgtcagg
     2821 catagcgata tgcctgacat ttttcgcata ctcctgtgct acaccggaga aaacggaaaa
     2881 caagacagac tttaccgcat atgtagatcc ttatatcgga tcgggagagc acggacacgt
     2941 atttgtcggg gcgaacgttc cgtttggagc tgttcaagta ggtcctcaga atatttttaa
     3001 gggatgggac tggtgttccg gttatcatta ctccgatagt atcattatcg gatttagtca
     3061 tacgcatttg agcggaaccg gatgttctga tctgggggat atccttctga tgccttatac
     3121 gggcgaggta cgtaccgccc gtggcgagca agataatata gagggagccg cttcttccta
     3181 ttataaacat gccaacgaag ccgtagctcc gggatattac tctttgctga tggataatgg
     3241 cgtaaaagcg gagttgacgg caaccgagcg tgtagcttta catcgttata cgtatccgtc
     3301 gggaagcgag catcgcctct tgatcaactt gaaggaaggt atcggtgata aagcgtatga
     3361 cacttatttg aagaagattg atgagtacac gatcgagggg taccgttttt ccaaaggttg
     3421 gagcccacgt cacaaagtat tctttacgtt gaaatgtgat cagccgatcg agtctttggc
     3481 tgtattcaac gatgatgagg ccgcgggtaa tgatgagttg acaggcgagt ccgtaaaggg
     3541 agtgattacc tttaagggag atgccccgac cgccttggta aaggtcgcta tctcttccgt
     3601 aagttgtgag aatgccttgg ctaacttacg tacggagctt tctcattggg atttcgacga
     3661 ggttcgtaac gaggctatcg ataaatggaa tgaccaattg tcttgtatct ccatcgatac
     3721 gaaagatgag cgtgccaaga aggttttcta taccgccatg taccatgcgt ttatcgctcc
     3781 gacgttgtat tgcgacgcga atggcgattt ccgtggccat gatgataagg tgtatacgaa
     3841 caatacttgg aagaactatt ccactttctc tctatgggat acgtatcgta ccttgcatcc
     3901 gttgttcacg attatcaagc ctcaatatgt gtcggatttg gtgaactcta tgttaagcat
     3961 ttacgaccag caagagaaat taccgatctg gccgttgatt ggtggtgaga cggatcaaat
     4021 gccgggatat agcgctgtgc ctattatcgc ggatgcctat ctgaaaggtt ttaccggctt
     4081 tgacgccgac cgtgcgtatc gttatatggt tgcttcctct gtctatgaga agcaaaacgg
     4141 ggtgccgtac gtgttggaaa aaggctatat cccttgtgat aaggtacgtg aggctacttc
     4201 tatcgcgatg gaatacgcag ccgatgattg gggtatcgcc ttgatggcga agaaaatggg
     4261 caagacggag gattaccaga attacttgaa acgtggtaaa tattatacgc agtatttcga
     4321 taaggatatc aactttatcc gtccgaaaat gaatgatggc agctggcgta cgccgtacga
     4381 tccgatccag tccatacata gcgtaggcga tttctgtgag ggaaatggtt ggcattatac
     4441 attcttcgtg ccccagcatc cggaaggctt gatcgagttg atgggtggcg acgctccgtt
     4501 tatctcgaaa ctggattctt tgttcttggt ggaaggtgag ttaggagaga acgcctctcc
     4561 ggatatcagt ggcttgatcg gcatgtacgc ccatggaaat gagccgagcc atcatgtcac
     4621 ttatctttat ccttacgccg gcgagcaatg gaagacagcc gagaaagttc gttacatcca
     4681 agatgtgttc tataccgacc agccggaggg catcatcgga aacgaggatt gtggccagat
     4741 gtccgcttgg catatcatgt ctgccttggg attttaccaa gtaaatcctt ccaatggcgt
     4801 gttcgtgttc ggtagcccgt tattcgataa ggcttccgtt catttgccgg agggtaagac
     4861 tttcgaggtc gtagcccaga acaacagcaa ggagaatgta tatatccaat ccgtgttgtt
     4921 aaatggtaaa ccttataaca attcttatat cctgtatgat gatatcgtga agggagggaa
     4981 tcttaccttt gtgatgggaa gtacaccgaa taaggagttc ggagctgccc cggaaaatcg
     5041 tccgaagacg gctgagtaaa tagctccctt actagtgagc ggcttgctca gttactagtg
     5101 agacaacgtc tcacggattg ccgggaaagt acccggctga gaagcaaaga ataattaacg
     5161 aattaataat cgacaaaatg aagacaaagc ttaaaacttc gatggccctt ttggcttccg
     5221 ctttcctgtg ggtgtcatgc gccggtgggg gagggacttc tccttcggcg atggacccgg
     5281 tggattacgt gaatccttat atgggaaaca tcagccattt attggtgcct actttcccga
     5341 ccgtgcattt gccgaacagt atgctacgtg tatatccgga gcgtgcggac ttcacgggcg
     5401 accgtctggg cggtttgcct attatcgtga caaaccatcg tgagcgttct gcgttcaatt
     5461 tatgccctta tcaaggtgac gaatccggct tgcgacccgt gatcgcttat agctatgacc
     5521 gggagaagat tttgccgtac cgttatcagg tatatctgga taatgaggaa atcgacgtgg
     5581 acttcgcccc gtcccatcaa agtgccgtat attcgctcac tttcgagaaa gagggaccgg
     5641 cttatctggt atttaacagc cgtaacggac agctacaagt aaatggtaac gccgtaagcg
     5701 gttatcaata tatagataag aaaacgaaag tctttttata tgccgagacg aaccagaagc
     5761 ctgtgaaagc gggggtattg tcgaacggca gtgtcaacta taacgagact tccgtggaag
     5821 gtatcaatgc cgctatcgcc ctttccttcg gggaggacgt gaagaaactt ggcgttcgct
     5881 acggtatctc ttttatcagc gaggaacagg cgaagaagaa tctggagcgt gagatcgccg
     5941 cttacgacgt ggatgtggta gcgaagatcg cccgcaacga ttggaacgac gctttaggta
     6001 aaatacaagt acaaggcggt accaaggatg agaagaccgt attctatacc tctttatatc
     6061 gttgctacga acgcccgata aacttgagcg aggacggaca ttattacagt gctttcgacg
     6121 gaaagatcca tgaggatggc ggacggtctt tctatacgga cgactggatt tgggatacct
     6181 accgtgctac acatcccctg cgtgtcttga tcgataatga gcgtgagaac gatatcatca
     6241 actcttatct cctgatggcg gagcagatgg gtaccgattg gatgcctacc ttcccggagg
     6301 tgacaggaga tacacgccgt atgaactcaa accatgctgt cgctaccgtg atcgacgctt
     6361 accgcaaggg cttgcgtggg tttgagctgg aaaaagccta tatcgcttgt aagaaaggta
     6421 tcgaggaaaa gaccttgatc ccgtggtctg ccgctcccgc cggttggttg gatgatttct
     6481 acaaggaaca tggctatatt cccgcattga gaccgggaga gaaagagacg gtgcctaacg
     6541 tatccatttg ggaaaaacgt cagccgatcg ccgtgacttt aggtacttcg tatgatgaat
     6601 ggtgcttgtc ccagatcgct caagaattgg gaaagaaaga cgaggcggat tattatttgc
     6661 gtcgctctta caattaccgg aacgtattta atccggagac aggtttcttc catccgaaag
     6721 ataaggatag caagtttatc tatccattgg attaccgtta tgatggcggt ctaggtgccc
     6781 gtgattatta cgatgagaat aacggatata tttatcgttg ggacgtacag cataatatcg
     6841 gtgacttgat ctctttgatc ggaggcaatg aggcgtttac ctctgccttg gattccatgt
     6901 tcaatacgcc gctgggtatg tctaaatggc aattctattc cacgcttccg gatcatacgg
     6961 gtaacgtagg tatgttctct atggcgaatg agccgagctt gcatatcccg tacttgtata
     7021 attatgcggg taagccttgg atgacccaga aacgtattcg taccttattg aatcaatggt
     7081 tccgcaatga tttgatgggt gtgccgggcg atgaggacgg tggtggtatg tccgctttcg
     7141 ttgttttcag ccagatggga ttctatccgg tgactccggg ttctcctacc tataatatcg
     7201 gtagcccgat gtttaccgac gtgaaagtgg atatgggtaa cggcaatacg ttcgagatcc
     7261 gtgcgaataa cgcatccgat gagaataaat acgtacaatc cgctaagttg aacggcgtaa
     7321 ccttgaacca gccttggttc aatcatagcg atatcgccgc tggtggtttg ttagagttag
     7381 agatggggcc gaaagcgaat aaggaatggg gattgggaac gcctcctcct tctgccgctc
     7441 cgatgcctaa gtaaaaaaaa gcgtgttgcg attgtcgcaa cacgcttttt tatgccaata
     7501 ccttaacgat taatttcttt agttctttta tatcaatggg cttcactaca taatccgtga
     7561 attcacattg tttggcgatc tccttttccc tttcgaaagc gaatgccgtg agcgctatga
     7621 tcggaatggt cttggataag gtgcggattc tgcgagtcgc ttcgaatccg tccataaccg
     7681 gcatttttat gtccatcagg attaggtccg gatgatatgt ctcgaacata tcgatagcct
     7741 cttgcccgtt tagcgcatga taaagttggt attgcttgcc aaacaaggtt tccaaaagga
     7801 aataattctc ataaacgtcc tcggcgatta agatggaatg atgcctatct gaacggggcg
     7861 tttcttcgga ttggacgggg atatccggtg aaagctcaat atcagtccgt tttgtgtcca
     7921 aaggcagagt gaaccaaaaa gtggaaccca ccccttcttc agagtctacg ccgattttac
     7981 ctcctaatgc ctcgataatg gttcggctga tggttaatcc caatcccgta ccttgctgga
     8041 aagtatctac cttgatgaat cgctcgaata tacgtctttg gttttccgcg gagataccga
     8101 tacctgtatc tttcacgcag actcggataa aatccccttc tatctcataa taaatcgtga
     8161 tacttccttt tgtggtaaat ttgatagcgt tattcacgaa attagatatc acttgcataa
     8221 ccctccgctc atcggtttta acgattacgg atggggagcc gagatcaaag ataagaacca
     8281 cgtctgaagg catctttata gagtctgcca atgcgatttc gccacatata tccttgatgt
     8341 ccacttcctc gaaatgataa tccatggttc ccgcctcgat tttagagaaa tcaaggatat
     8401 catcgatcag ttgcagtagc aaatcattgt ttttatgaat gatatctaaa taagattgac
     8461 gctctacctc atcatcaatc tcggcgatta tatttgagaa cccgacgata gcgttcagcg
     8521 gcgtgcgtat ctcatgactc atattcgcca agaatgcgga cttcaattta tcagcttcct
     8581 ttaccttgat tagctcgatc tccttttccc gttgctgggt tatgttggag gtatagctta
     8641 cgatcctgtt aggcgttccg tcatcgttga atttatagga gcgtacattg gagttgaacc
     8701 agaatgtttt gccattgagg atacgcctgt aggccgctac gaagttattg atcttccctt
     8761 gcaggagagg tttgaactgt ttattatata cccggtcaaa atcatccgga tggattgagg
     8821 atttatagtc ttcttgattc ttgaagttgt aatcatgaat cgcttttagc ccctcattat
     8881 tattaatgtc ttcattgaga ccaaaatcta cggtcaattt atcattctct acatcgtatt
     8941 cccaaagaat ggaatccccg gtatctactg atacttttag ccgggctagg ctattttcga
     9001 tttgttcccg cttgatgtga ttctcggtat cgtcgaatac aatataaata tagccgaata
     9061 tattatcaag agagtctttt aatgtgactc cttttaccaa cagatgcttt gttttagaat
     9121 catgatgact atcgtaatag ccgttttgag aagcaacctt gaaatcataa ttaagaggaa
     9181 agaatatatc ttttccgttt ttgaggcttt ggtttacata tttcgggata ttaggattct
     9241 cgaacatatt cagtcccacg gcctgctcac gggtaacacc aaaaatatcg agatccgctt
     9301 ggttgatatc taccaacact ccattctcat cataaagttc ggcgccccaa ggcatcttgt
     9361 cgaaaatgat cttaaacttc gtctcgcttt tcatgacttg catagccgta tgttctacta
     9421 atccttgaac ttcccctctt tcaatggcta tggaaaggat atcagccaac atatgtaagt
     9481 tctctatatc taaggcactc cagttccgtt tcttttttac agaatcaaag ccgataaatc
     9541 cggatggttt gccttgcttg aaaataggga tgactaataa ggatgaaacc tcttgcaaaa
     9601 tcagaagatg ctgctcactc ttcgcctctt ccggcatttt agagacatca tgaataacga
     9661 tatccatgcc ctttttgata ctgtcgtacc accaaggaat ctcgtcttgc gggagttgac
     9721 gcagtaaatc ctctcgcata gagataatgc catcacaagt aacttcattc gtaaaatcaa
     9781 cagtatgagt ttgttcgtca aatgttccga tatacacccg atccacatcg aaaaattgta
     9841 agatgcggaa tagcgcttgg tcaataaccg agtttttttt ggctccaaga agaagtgaca
     9901 atacatccga catcgttttt cgcaaatcaa tcatattggc caaaatcaag tcggtctttt
     9961 catcttctac atcggtcttc ttgtctatag cctcattaag aaatgttgta ttggaatgaa
    10021 tgttattcat gataaattga gtgtactaaa tttattcgaa aacaaatgta agtataaact
    10081 ttgattattt tttgttttag tgtttattat attattatcg tggctttaaa aataattttg
    10141 tacgtttgta gatggttgaa ttaaacttga aatctatgga taataaaatc atattgacga
    10201 taggccgcca gttcggaagc ggtggccgcg agatcggaca acgtttggcg aaggagttgg
    10261 gtatcggtta ctatgataag gaactgatta ccgtggcggc ccgtgagagt ggattatgcg
    10321 aggatgtttt cgagaaggca gacgaacgtg cctccagtgg tttatcgtac gcttttacga
    10381 tggggtattc ttcttttatg ggagggatgt ttacgcctta taatgatatt ttgtctaatg
    10441 acggtctttt taagatacag agtgacgcta tccgtaaatt ggcggagact gagtcgtgtg
    10501 ttttggtagg gcgttgcgct gattatatcc tccgggataa tccggcttgt ttgagcttct
    10561 ttatccatag ttcagtggag agccgggtcc aaaagaccgt ggaaaggcat ggtgtgacgg
    10621 tggaagaggc gaagaacatg atggagaaga ctgataaatc ccgtgcggct tactataatt
    10681 attatacgaa taagacatgg ggaatggcct cttcttataa tttctcgatc gatgtatccg
    10741 tattagggat cgacgagacc gtggaattta tgaaaagctt tatcgagcgc agattgaata
    10801 agcgtccgcc tcatttcgga taaatcgtat tcttgagaaa ccattattga atagagatta
    10861 acctattaaa actaagaaag tatgcgaaaa ccttttatta ctgttcggct gacccatggt
    10921 atgttgggcg ccttgttagt ttccacctgt gcttgttcgg gcacgaagtg gacggaggtg
    10981 gagaaagatt ctatccgtat cgttacccag caagaaggag ctgtattagg atattccgcc
    11041 aattcggggg tgagacttct tactgttgac ggatatgcct tcaaagatct gaatcggaac
    11101 gggcggcttg atccgtatga ggattggcgt cttacgcccg aggaacgtgc cgttgatttg
    11161 gccggacagt atctacagag gaaatcgccg gattgatgct ttatagcgcc catcaatcta
    11221 tccccggtgc ctcgaaaggg tttggaactt ctacctacaa tggcaaatct tttgatgaga
    11281 gtggagccca gccatccgat ctttccgatg cgcagcgtaa attcctcacc gaggataatg
    11341 ttcgtcatgt attggttacg agagtgcaaa gcccgaaagt ggcggctcgc tggaataata
    11401 atgcgcaagc tttagtagag ggtatcggtc atggtatctt acggtcgttg ataatcccga
    11461 tgaggcggat ttcgccatcg tctttatgac gagcccgaac agtggtacgg ggtatgataa
    11521 atccgattgt gagaaaggtg gaaacggtta tatgcctatc agtttacagt ataatgatta
    11581 taccgctacc tatgcccgta acccaagttt ggcgggggga gatccgtttg agaatttcac
    11641 gaaccgttct tataaaggta agtccgtgaa aacagctaat aagcaggata tgctttctgt
    11701 tttggagaca aaggctaaaa tgaaaggtaa gcctgtaatc gtatctttgg agatggataa
    11761 gcctacgatt atgtccgagt tcgagggttc ggcggatgcc attctggtga acttcggtgt
    11821 acaaaaccaa gcggtcttgg atatcatcag tggaaaagcc gagccttccg ctttgttgcc
    11881 tttgcagatg ccggcagata tgcgtatcgt ggaggagcaa ttcgaagatg ttccccggga
    11941 tatgaaatgc tatacggata gcgagggcca tctgtatgat ttcgcttttt gtatgaattg
    12001 gaaaggcgtt atcgattatg agcgagtgac taaatataaa tagagtaaat tacatttttg
    12061 tgtttttgtg gctacggtat ctatatataa tgcctaaatt tgcatggtaa tattattaag
    12121 tgcagaccat gaaaattatg acattgcagg gaacggacaa attgttatat gaacttgtcg
    12181 cacctttggt catgaatcca gccattttgc gacaaaataa caattaccct tttaaaacat
    12241 ctcgtagcca cgtttggtat atagcctttc atgaaacagc tgttgttggt tttatgcctg
    12301 taaaaaaagg acatctctat tactctatag acaattattt cgtgagtggt gatgatcctt
    12361 cggtattgag tgaacttctt gaagaagtca taaaggattt ttcatctcaa gcttcactta
    12421 tggctgttgt gcataaacgt catgtaaaag tgttctcaca aaaaaagttc cagacatgtg
    12481 ttgagtggaa aaattatgat aaaatgcatt atttaccgga ggtagagtca tgatgcgaag
    12541 aatggatgtg tacgaggcga cagagaaaag attgaagatc atttttgatt atttcgatta
    12601 cgtatacgtc tctttttccg gcggaaagga tagtggtgta ctgttgaatt tgtgtgtaga
    12661 ttatattcgt agatacgctc cgggacgaaa attaggtgta tttcatatgg attatgaggt
    12721 tcaatacagc cagacgaccg aatatgtgga aaaggtttat gccgctaatt ccgatatcct
    12781 tgatatttat cattgttgtg ttccttttaa agtccagaca tgtacatcta tgtttcaaca
    12841 atattggaga ccttggagcg aggagtaccg ggatatctgg gttcgagaga tgccccattc
    12901 atgtctccgg gcgaaagact ttgacttttt caaggaggac atgtgggatt atgattttca
    12961 gaatatgttc cctttttggt tgtatcaacg gaaaatgggc cggcgtatat gttgccttgt
    13021 tggtatccgt acccaagaga gttttaatag gtggcgggcc atacatagtg ataagaatta
    13081 cagaaaacta gctaattata aatggactcg cagaatgaat tattctatat ataacgcata
    13141 tcctatttat gattggaaaa ctcaggatat ctggatagcg aacggaaagt tcggttggac
    13201 atataatcat ttgtatgatt tgtattatca agcaggggtg cctttgtccc ggcaacgtgt
    13261 ggcgagccca ttcatatccc aagcgatatc cacactgttc atttacaaag ttgtcgatcc
    13321 cgacatgtgg gggaggatgg ttggacgtgt aaacggtgtt ggctttgccg gtatatatgg
    13381 gaatacctcc gctatgggat ggagggctat caagtgccca gccgggttct cttgggagaa
    13441 atatatgtat tttctcctaa atactttacc cgaagaaact cgtgagaact atttgaataa
    13501 gttaagagtc agccgtaaat tctggagaga aaaaggagga tgcctcagtg aggagactat
    13561 cgctaagtta cgggcggcta atattcctat cattgtggaa gaatgtaccg cttaccatac
    13621 ggataagaaa ccggtacgga tggagtatat cgatgatatc aatatacccg agtttaaaga
    13681 aatccctact tacaaacgta tgtgtgtttg tattttgaaa aacgatcata catgcaagta
    13741 tatgggtttt tcccagacaa aacgagagag ggatatgaga aaagaagtaa tggacaaata
    13801 taatttttat aagcatggga aactttgtta gtccggcata tggtgttagg gctgtcccta
    13861 tagaaaaaat tgtagccaac agctataacc ctaatatcat ggcaccaccg gaaatgcgat
    13921 tattggaact ttccatttgg gaggatggct atacgatgcc ttgcgtctgt tattatcttg
    13981 aagaggatga tttatatgag atagtagatg gttatcatcg ttatctggtt atgaagcaat
    14041 ctcaaaggat ttatgatcgt gagaaaggaa tgttgcctgt aacggtgatt gagaaagata
    14101 tttcaaaccg aatggcttca accattcgcc ataacagggc tcgagggatg cacaacttgg
    14161 aacttatgac ggagattgtt acggagttgg tcaaatctgg gatgtctgat aagtggatca
    14221 tgcgtaatat tggaatggat aaaaatgagt tacttcggtt caagcagatt tcgggattag
    14281 ctgaattatt ccgggataaa gaattcggtt ggtctgatga ctggtcggaa gaaga
//
LOCUS       DBMDTB010000098        14313 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_1327_length_14313_cov_12.614129, whole genome shotgun
            sequence.
ACCESSION   DBMDTB010000098 DBMDTB010000000
VERSION     DBMDTB010000098.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 14313)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 14313)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14313
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1327_length_14313_cov_12.614129"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..801)
                     /locus_tag="ACZPB4_13645"
     CDS             complement(<1..801)
                     /locus_tag="ACZPB4_13645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIR1099293.1"
                     /translation="MNVTDLPQACISLIENVPGIDFIDEDFAIFDNIDDIPSLDHPMR
                     IDAVVFALCTKGFMRIRINMEEYVVGENHLVLSLPDQIIQHVERSEDVAGIFIVISKN
                     FMEEIIPHIQNTLPAFFYIKEHPVTELNTEEIGCIKEYHSFLWKKVKAKGHPYRKEIA
                     QSLLLAVFHEVYGMFKNHMPIEVKKSRQEELFAAFIQTLALHHKQERSVAFYAGKLCV
                     TPKYLSLLVKNVSNRTAGEWIDNYVVLEAKALLSSSTLSIQEISDRLNF"
     gene            947..1978
                     /locus_tag="ACZPB4_13650"
     CDS             947..1978
                     /locus_tag="ACZPB4_13650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HIR1099294.1"
                     /translation="MKRMKGIVYGGLLSVVFVMSGCSGSQKEGRDSKEIPVEIVKVAK
                     TVPADTRNYVGTVEEVVSSSISFQVMGNVERVLVGEGQKVREGQLLAVLDKATLENAY
                     NASAASLRQAEDAYARMRTLHENKSLPDMKWVEVESKLEQARSMERISRKNLEDRNLY
                     APFGGVIGKRMVEAGENVQPGQPVFSLLRIETVNVKIAVPENEVATLGDQAAMIKVAA
                     LGGQCFEGKVTEKGIVANPISHTYEAKIRLENPSGALLPGMVCDVRLSGEESVPAIAL
                     PNNAVLIANDGGRFVWKVVDGEAKATPVRTGDLTEQGLFILEGLNEGDIVVIGGYQKI
                     SEGMRVRAL"
     gene            1975..5055
                     /locus_tag="ACZPB4_13655"
     CDS             1975..5055
                     /locus_tag="ACZPB4_13655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0042908 - xenobiotic transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HIR1099295.1"
                     /translation="MRERKNGVIEWTMRHYQITLLVITVLVGLGIWGLVDMPKQEFPE
                     FTIRQGVVVGVYPGATSGEVEEQLAKPLERYLFTFKEVKKKKTYSMSRDGMVYVMVEL
                     NDDVNNKDEVWSKIKLGLQNFKSQLPSGVLAVIANDDFGDTSALLITLESEDKTYREL
                     QRYMETLEDRLRRIESVSNLRRYGVQNEQISVYLDPDKLAAYGLDTRMLMTTLFTQGF
                     TTASGSLENGGLDIPIHLSVTYPSEREVGEQILLADADGHMIRLKDVARIVREYPEPD
                     SYITNNGKKAIILSMEMREGHNIVRYGKEVDEVLHAFERDLPGSVSIRRIADQPKVVG
                     DSVSSFVRDLFVSIVVVILVMMVLFPFRSALVAATSIPISVFISIGVMYACGIPLNTV
                     TLAALIVVLGMIVDNSIIVIDAYLEYLDKGYSRWYAAVYSAKNYFSSILLATLCICVI
                     FFPLLFTMTGQMLDFVTFFPWTLSISLMVSLAVAMVFIPLLERVLIKKGLKSGRENTG
                     KKRFNLLDTVQAVYTRALTWTFRFPKATIGLGILTVALAILMITQLSQRMMPIADRDQ
                     FAVEIYLPQGTSLDRTAAVSDSLYKLLSEDERILSVTSFIGTSSPRFQATYAPNLAGK
                     NYAQFIVNTASVEATRSVLDDYTDRYADYFPDAYVKFKQLDYQNVSSPLEVRFMGDDI
                     ARLKQAGDSLMAVLREMDGLVWVHTNYEEALPDVRVRLDPVEASRLGITKAMASADLA
                     IRYDGLSVGSLWEGDYALPIQLRSDKKGEGDAFDKVGDQYLPTIVPGVSVPLRQVSTI
                     EGGWNDGQIVRRNGVRTLSVFAEVTRETNQNAMQKRIERVMESRIIPTLPEGVTYEYG
                     GAKELDFETMNPLMQGLAIAVIIVFFFLLVNFKKIGLALAALSSLLLTLFGAALGLWA
                     FHIDFSLTCVLGVISLIGIVVRNAILIFEHAQDLRLHKHYSPRDAAFDAGRRRMLPIF
                     LTSATTAVGVVPMIISGSSLWMPMGVVICSGTVFSMILAVIILPVFYWKIFGNK"
     gene            5098..6393
                     /locus_tag="ACZPB4_13660"
     CDS             5098..6393
                     /locus_tag="ACZPB4_13660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HIR1099296.1"
                     /translation="MRKKEMIKRWIYGIVGSLVLCVGTVSAQRTLSLEECREMALENN
                     AKMKNARLDVEGAREGKKEAFTKYFPNVSAVGTAFKANHGMMDMSVIPGLLELSMMDD
                     GLLGGVTAIQPVFAGGQIVNGNKLADLALEVSRYQMRQSEDEVALTVERYYWQWISLH
                     EKLRTIEIVESLVGSLYKDVEVAVGAGVTTRNDLLQVQLKKNGVASDRLRVENGLRLS
                     KMVLAQYIGIGEDDFEIDFTLPAEVPSPELYRVSHEEALPTTLSYKLLEKNVEAARLQ
                     QKLKVGQYLPTVGIGAGYMYHNLLDKDRPFGMVFATVAIPISDWWGGSHAIRKQKLQV
                     KAAEYSRQNANELLLVQMRKLWNELEESYKQVKLSEESIATAEENVRLNTDYYKAGTV
                     TLSDLLDAQSLLQQSRDQYTGDYTAYLIKRTEYLQATGR"
     gene            6447..7256
                     /gene="cysQ"
                     /locus_tag="ACZPB4_13665"
     CDS             6447..7256
                     /gene="cysQ"
                     /locus_tag="ACZPB4_13665"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008441 - 3'(2'),5'-bisphosphate
                     nucleotidase activity [Evidence IEA];
                     GO_process: GO:0006790 - sulfur compound metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3'(2'),5'-bisphosphate nucleotidase CysQ"
                     /protein_id="HIR1099297.1"
                     /translation="MMSYANYLYIAIRAAVDAGKSIMDIYNDPESDFGIERKADNSPL
                     TKADKAAHRLITNALSVTPFPVLSEEGKEIPFKERSKWETLWIVDPLDGTKEFIKKNG
                     EFTVNIALVEKGVPVLGVIYVPVRKELYFASSSVGAYKFTGIDSSSQPSMDEMKQGAI
                     HLPMALAHQGIVVVASRSHQTEETTAFIDNLRKQGKPVTLISSGSSLKICLVAEGSAD
                     IYPRFAPTMEWDTAAGHAIAKSAGCDIYHIDGKTPLRYNKEDLHNPWFIVK"
     gene            7503..9056
                     /locus_tag="ACZPB4_13670"
     CDS             7503..9056
                     /locus_tag="ACZPB4_13670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009039350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0006811 - monoatomic ion transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HIR1099298.1"
                     /translation="MNFDIVFVLLALIGMIAALVWDKMRPGMVLLTVVVFFLCVGILT
                     PKEMLEGFSNKGMITVAMLFLVSEGVRQSGALGQLIKKLLPEGKTTVFKAQARMLPPV
                     AFVSAFLNNTPVVVIFAPIIKRWAEAVRLPATKFLIPLSYVTILGGICTLIGTSTNLV
                     VHGMILEAGYEGFTMFELGKVGIFIAIAGILYLFAFSNKLLPDSRTDTVSEDGEDENP
                     GNFHRVEAVLGARFPGINKTLGEFNFTRHYGAIVKEVKSGGQRFTRNLDTVVLHEGDT
                     LVLWADDSFIPTWGESSVFLMLANGNEATEPVSRKKRWLALGLLIFMITGATVGELPV
                     VKEAVPSMRLDMFFFVCITTIIMAWTKIFPPKKYTKYISWDILITIACAFAISKAMEN
                     SGFASMIARHIISMADDLGPYALLAIIFIITNIFTELITNNAAAALSFPIALSVATQL
                     GVDPTPFFVVICMAASASFSTPIGYQTNLIVQGVGGYKFTDFVKVGLPLNLITFLISV
                     FVIPMIWKF"
     gene            9044..9655
                     /gene="cysC"
                     /locus_tag="ACZPB4_13675"
     CDS             9044..9655
                     /gene="cysC"
                     /locus_tag="ACZPB4_13675"
                     /EC_number="2.7.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004020 - adenylylsulfate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000103 - sulfate assimilation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylyl-sulfate kinase"
                     /protein_id="HIR1099299.1"
                     /translation="MEVLENNIYPIFDRMLGREDKEALLGQRGVMVWFTGLSGSGKST
                     IAIALERELHKRGLLCRILDGDNIRSGINNNLGFSPEDRVENIRRIAEVGKLFVDTGV
                     ITIAAFISPNNELREMASAIIGKADFLEVYVSTPLAECERRDVKGLYAKARKGEIKEF
                     TGVSAPFEAPERPDLSLDTSVLSVEQSVNRLLELIVPKVEIKH"
     gene            9664..10572
                     /gene="cysD"
                     /locus_tag="ACZPB4_13680"
     CDS             9664..10572
                     /gene="cysD"
                     /locus_tag="ACZPB4_13680"
                     /EC_number="2.7.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004313239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004781 - sulfate adenylyltransferase
                     (ATP) activity [Evidence IEA];
                     GO_process: GO:0000103 - sulfate assimilation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate adenylyltransferase subunit CysD"
                     /protein_id="HIR1099300.1"
                     /translation="MSDYKLSHLQELEAESIHIIREVAAEFENPVMLYSIGKDSSVMV
                     RLAEKAFAPGKVPFPLMHIDSKWKFKEMIEFRDSYAKKFGWNLIVESNMEAFHAGVGP
                     FTHGSKVHTDLMKTQALLHALDKYKFDAAFGGARRDEEKSRAKERIFSFRDKFHQWDP
                     KNQRPELWDIYNARVHKGESIRVFPLSNWTELDIWQYIRLENIPIVPLYFAKERPCVE
                     IDGNLIMADDDRLPEQYRDQIRMRMVRFRTLGCWPLTGAVESEADTIEKIVEEMMTTT
                     KSERTTRVIDFDQDASMEQKKREGYF"
     gene            10585..12027
                     /gene="cysN"
                     /locus_tag="ACZPB4_13685"
     CDS             10585..12027
                     /gene="cysN"
                     /locus_tag="ACZPB4_13685"
                     /EC_number="2.7.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006790 - sulfur compound metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate adenylyltransferase subunit CysN"
                     /protein_id="HIR1099301.1"
                     /translation="MADTKLNIKEFLDKDEQKDLLRFLTAGSVDDGKSTLIGRLLFDS
                     KKIYEDQLDALERDSKRMGNAGEHIDYALLLDGLKAEREQGITIDVAYRYFSTNNRKF
                     IIADTPGHEQYTRNMITGGSTANLAIILVDARTGVITQTCRHTYLVSLLGIKHVVLAV
                     NKMDLVDFDKDTFDRIVADYKRFVEPLDIPDITYIPLSALDGDNVVEKSDRTPWYEGT
                     SLLDYLENVPIDLDRNYEDFRYPVQYVLRPNLDFRGFSGKVASGIVRKGDTVMALPSG
                     KTSKVKSIVTYEGELEQAFPPQCITITLEDEIDISRGEMLVHPDNLPIRDRNFEAMLV
                     WMDEEAMDVNKQFYIKQTTHTTRARVDSIRYKVNVNTMEQSSVDHLELNEIGRVVFTT
                     GKELFFDPYRRNKQTGSFILIDPITNNTSAVGMIIDRVDAKDMVTEDALATLNLPEMG
                     IGEEHYEAIRKVCEELGRQGVSVKCITEKR"
     gene            12031..13134
                     /locus_tag="ACZPB4_13690"
     CDS             12031..13134
                     /locus_tag="ACZPB4_13690"
                     /EC_number="2.8.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005638233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008146 - sulfotransferase activity
                     [Evidence IEA];
                     GO_function: GO:0050656 - 3'-phosphoadenosine
                     5'-phosphosulfate binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfotransferase family protein"
                     /protein_id="HIR1099302.1"
                     /translation="MGLLEFDKLPINTLVGADWDTFRKVTARQQIDKGFKGKYRLTTG
                     VCRLLSALKPIEDSRFKKLADKPLEMDPLFILGHWRSGTTFVHNIFACDKHFGYTTTY
                     QTVFPHLMLWGQPFFKKNMAFLMPDKRPTDNMELKVDLPQEEEFALSNMMPYTYYNFW
                     FFPKRWMEYCDRYLLFNDITEEERRIFMDTFMRLVKVSLWNTNGTQYLSKNPPHTGRV
                     KTLLEMFPNAKFIYLKRNPYTVFESTRSFFTNTIQPLRLQDITNEQIEANFIEVYRRL
                     FYKYEEEKHLIPEGNLVEVKFEDFEKDAFAMTENIYGSLNLPGFKESKADIEKYLGKK
                     KGYKKNQYKYEDRTVRLVEENWGMALKEWGYSL"
     gene            13171..14154
                     /locus_tag="ACZPB4_13695"
     CDS             13171..14154
                     /locus_tag="ACZPB4_13695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PCMD domain-containing protein"
                     /protein_id="HIR1099303.1"
                     /translation="MGLSLRKKALFLAIACMPLSVVLADGDGVTSENVVPFAYGDMDN
                     WIVREIHESGIIGGNTKWLYELGPSDTIVGNTAFRNMGGSPWATSNVMAKVAGVVKTN
                     TSVFPEKRGDGMCARMETRYESVKVFGLVDIEVIAAGSVFLGTVHEPIKGTKNPQAML
                     QSGVPFSKKPKALRFDYKVKAAPEKNRVRSTGFSRKSTVAGQDSLAVILLLQKRWEDA
                     EGNVYSKRVGTMVQRYTESTPDWVNDATYPILYGNITSKPEYKPYMRIQVEERYTLNS
                     KGKSVPIQEVGWAEPGEAPTHMVLQFTSSHGGAYIGSPGNTFWIDNVELIY"
     gene            14156..>14313
                     /locus_tag="ACZPB4_13700"
     CDS             14156..>14313
                     /locus_tag="ACZPB4_13700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA ligase LigA-related protein"
                     /protein_id="HIR1099304.1"
                     /translation="MVEAKIKALRDELERHNYNYYVLSAPTISDFEFDKMMKELQELE
                     AAHPEFADP"
BASE COUNT         3399 a         3210 c         4229 g         3475 t
ORIGIN      
        1 gaagtttagc cggtctgata tctcttggat ggaaagggtg gaggaggata ataacgcctt
       61 cgcctccaag acaacgtaat tatcgatcca ttccccggct gtacggttgc tgacgttctt
      121 taccaaaaga gataaatatt tgggagtcac acataatttc ccggcgtaga aagctaccga
      181 tcgttcctgc ttatgatgta aggcgagcgt ttgtatgaac gccgcgaaca actcctcttg
      241 ccggctcttc ttcacctcga tcggcatatg attcttaaac atgccgtaaa cctcgtggaa
      301 taccgccaac aataagctct gggcaatctc tttccggtaa ggatgccctt tcgctttcac
      361 ttttttccag aggaaagaat gatattcctt gatacaacct atctcctcgg tattcaactc
      421 ggtgaccgga tgctccttga tgtagaagaa cgccggcaag gtattctgta tatgaggaat
      481 gatctcctcc atgaaattct tggagatgac gatgaagatc ccggccacgt cctcgctacg
      541 ttccacgtgt tggatgatct gatcaggcaa ggacaatacg agatggtttt cccctacgac
      601 atattcctcc atattgatcc gtatacgcat gaagcctttc gtacaaagcg cgaatacgac
      661 ggcgtctatt cgcatcggat ggtcgagcga gggaatatcg tcgatgttat cgaatatggc
      721 gaaatcctcg tcgataaagt ctatgccggg tacgttctcg ataagagaga tacaagcttg
      781 aggtagatct gttacgttca taatttattc ttgtttgggc gataaaatta gtgaaataat
      841 agaataatcc aattgaaatg tgtcaaatag gacaatttgg ttgcaaaacg gaacttcttt
      901 ggagtggata aactcatcat cttcgcggta taataaatca taggatatga aaaggatgaa
      961 aggcattgtt tatggaggat tattatccgt cgtgttcgtg atgtccggat gctcgggcag
     1021 tcaaaaagag ggacgggata gcaaagagat cccggtggag atcgtgaagg tagcgaagac
     1081 cgttccggcg gatacaagga attacgtggg aacggtagag gaggtcgtat cctcctcgat
     1141 tagttttcag gtgatgggta atgtagagcg agtattggtg ggcgaggggc agaaggtccg
     1201 tgagggccaa ctactagcgg tgttagacaa ggcgacgctg gaaaacgcct ataacgcctc
     1261 ggccgcttcc ttgcgacaag cggaggacgc ctatgcccgc atgagaacct tgcacgagaa
     1321 taagagcctg ccggatatga aatgggtaga ggtggagagc aaattggaac aggcccgttc
     1381 catggagcga atctcgagga aaaaccttga ggaccggaac ctgtatgccc cgttcggcgg
     1441 cgttatcggc aagcgcatgg ttgaggcggg agagaacgtg cagcccgggc aaccggtttt
     1501 ctccttgtta aggatagaga cggtaaacgt gaagatcgcc gttccggaga atgaggtcgc
     1561 cacgctcggc gatcaagccg ctatgataaa ggtagccgct ctgggcggac aatgttttga
     1621 ggggaaagtg acggagaaag gtatcgtggc caaccctatc tcccatactt acgaggcgaa
     1681 gatccggctg gagaacccgt ccggcgcttt gttgcccggc atggtttgcg atgtacgcct
     1741 gtcgggagag gaatccgtgc cggctatcgc cttgccgaac aacgccgtgc tgatagcgaa
     1801 cgacgggggg cgtttcgtct ggaaggtcgt agacggagag gcgaaagcta cgcccgtacg
     1861 gacgggcgac ttgacggagc agggcttgtt tattctggaa gggttgaacg agggggatat
     1921 cgtcgtgata ggcggttacc agaaaatcag tgagggcatg agagtgcgtg cgttatgaga
     1981 gaacgtaaaa acggagtgat cgaatggacc atgcgtcatt accagatcac gttgctggtg
     2041 attaccgtgc tggtcgggtt gggtatttgg ggtttggtgg acatgccgaa acaggaattc
     2101 ccggagttca ccatccgcca aggcgtggtc gtgggtgttt accccggggc gacttccgga
     2161 gaggtggagg agcagttggc caagcctttg gagagatacc tgtttacctt caaggaggta
     2221 aagaagaaaa agacgtactc catgtcaagg gatggaatgg tgtacgtgat ggtggagctg
     2281 aacgacgacg tgaacaataa agacgaggtc tggtcgaaga tcaagctcgg cttgcagaac
     2341 ttcaagtcgc aactgccctc gggcgtactc gccgtcatcg cgaatgatga tttcggcgat
     2401 acttccgcct tattgatcac cttggaatcg gaagacaaga cctaccggga attgcagcga
     2461 tacatggaga cgctggaaga ccgcctgcgc cggatcgagt ccgtatccaa cctgcgccgt
     2521 tacggggtac aaaacgagca gatctcggtc tacttggatc cagacaagct agccgcttac
     2581 ggcctagata cccgtatgct gatgacaacc ttgttcaccc aaggctttac caccgcctcc
     2641 ggctccttgg agaatggcgg cttggacatt cccatccacc tttccgtgac ttatccctcg
     2701 gagcgggagg taggcgagca gatcctgctg gccgatgccg acgggcatat gatccgcttg
     2761 aaagacgtgg cccgtatcgt gcgggaatat cccgagccgg atagctatat aacgaacaac
     2821 ggcaagaaag cgatcatcct ttccatggag atgcgtgagg gccataatat cgtacgatac
     2881 ggaaaggagg tagacgaggt attgcacgct ttcgagcggg atcttcccgg gagtgtctcg
     2941 atccgccgga tcgccgacca gccgaaggtg gtgggagact cggtaagttc cttcgtgcgg
     3001 gatttgttcg tgtccatcgt ggtcgtgatc ttggtgatga tggtattgtt cccgttccgc
     3061 tcggcattgg tggcggctac ctccatcccg atcagtgtct ttatctcgat cggtgtcatg
     3121 tacgcttgcg gcatcccgct gaatacggtg acgctggccg ccttgatcgt ggtattgggc
     3181 atgatcgtgg ataactccat catcgtgata gacgcctatc tggaatatct ggacaagggc
     3241 tattcccgtt ggtacgccgc cgtctatagc gccaagaact atttcagctc gatcttgttg
     3301 gctacgctgt gtatctgcgt gatctttttc ccgttgcttt tcacgatgac ggggcagatg
     3361 ttggatttcg tgaccttctt cccttggacg ctttccatct ccctcatggt gtcgctggcg
     3421 gtggcgatgg tctttatccc gctgctggag cgggtcttga tcaagaaggg attgaagtcc
     3481 gggcgggaga atacaggcaa gaagaggttc aatctgctgg ataccgtaca ggccgtctat
     3541 acgagggcgc tgacgtggac tttccgtttc ccgaaagcca cgatcggttt aggcatcctg
     3601 acggttgcct tggcgatcct gatgatcact caactgagcc agcgtatgat gccgatagcc
     3661 gaccgggatc agttcgccgt cgagatctat ctcccgcagg gaacctcgct ggaccgtacc
     3721 gccgccgtga gcgatagtct ctataagctg ttgtcggaag atgagcgcat cctgtccgtc
     3781 acctccttta tcggaacttc ctcgccccgt ttccaagcta cctacgcccc gaacttggcc
     3841 gggaagaatt acgcccagtt cattgtcaac accgcctcgg tagaggccac ccgtagcgtg
     3901 ttggatgatt atacggaccg ctacgccgat tatttccccg acgcttacgt gaagttcaag
     3961 caactggatt accaaaacgt atcctctcct ttagaggtcc gtttcatggg agacgatatc
     4021 gcccggttga agcaggccgg ggattccttg atggccgtgt tgcgtgagat ggacggcttg
     4081 gtctgggtac acaccaatta tgaggaggcc ttacccgacg tacgggttcg attggaccca
     4141 gtggaagcct cccgcctcgg gatcacgaag gcgatggcct cggccgatct ggcgatccgt
     4201 tacgacggcc tctcggttgg ctccctctgg gaaggcgatt acgctttgcc gatccagctg
     4261 agatccgata agaaagggga gggtgacgcg ttcgataagg tcggcgacca gtatcttccc
     4321 accatcgtcc ccggcgtgag cgtcccgctc cggcaagtct ccacgatcga gggaggctgg
     4381 aatgatgggc agatcgtccg tcgcaacggc gtgcgtacct tgagcgtctt cgccgaggta
     4441 acccgggaga ccaaccagaa cgctatgcag aaacggatcg agcgagtcat ggaaagccgt
     4501 attatcccga ccttgcccga gggcgtgacg tacgagtacg gtggagccaa ggagctggat
     4561 ttcgagacga tgaacccgct gatgcagggc ttggcgatcg ccgtgatcat tgttttcttc
     4621 ttcctgttgg tcaatttcaa gaagatcggc ttggcgttgg cggccctgtc ctcgttgctg
     4681 ctcaccttgt tcggggcggc gctgggcttg tgggcgttcc atatcgattt cagcttgacg
     4741 tgcgtcttgg gcgttattag cttgatcggt atcgtggtgc gaaacgctat cttgatattc
     4801 gagcatgcgc aagacctgcg gctccataag cattatagcc cgagggatgc cgccttcgac
     4861 gccggccggc gacgcatgct tccgatcttc ctgacctcgg ctacaacggc cgtgggcgtg
     4921 gtgcccatga tcatcagcgg cagttccctt tggatgccga tgggtgtggt gatctgctcg
     4981 ggaacggtct tctcgatgat cttggcggtc atcatcctgc ctgttttcta ttggaagata
     5041 ttcgggaata aatgaatgat acggatgtgg attaggatat aatataggaa tgaatatatg
     5101 cggaaaaaag agatgataaa aagatggata tatggcatcg tcggttccct cgtcttatgc
     5161 gtggggaccg tgagcgccca gcggacatta tcgctggaag aatgccggga aatggctttg
     5221 gagaataacg cgaagatgaa gaacgcccgc ttagacgtag aaggggcgag ggaaggaaaa
     5281 aaggaggcct ttacgaaata cttcccgaat gtcagcgccg tgggaacggc attcaaggcg
     5341 aaccacggga tgatggatat gagcgtgata ccgggccttc tcgagttgtc gatgatggat
     5401 gacggcttgc tgggtggggt gaccgctatc cagcccgtgt tcgccggcgg acagatcgtg
     5461 aacggcaata agctggccga cttggcgctc gaggtgagcc gttaccagat gcgccaatcc
     5521 gaggatgagg tagccttgac ggtggagcgg tattactggc aatggatctc ccttcacgag
     5581 aaattaagga cgatcgagat cgtggaatcc ttggtgggga gtctttataa ggatgtggag
     5641 gtagcggtcg gcgccggcgt gacgactcgt aatgacctac tgcaagtcca gttgaaaaag
     5701 aacggcgtgg cgagcgaccg cctgcgggtg gagaacggct tgcgcctctc caagatggtg
     5761 ctggctcaat atatcggtat cggggaagat gatttcgaga tcgatttcac gctgcccgcc
     5821 gaggtgccct ccccggagct ttaccgggtg agccatgagg aggcgctccc tacgacactc
     5881 tcttataaat tgctggagaa gaacgtggag gccgctcgtc ttcaacaaaa gctgaaggtt
     5941 gggcaatact tgcccaccgt ggggatcgga gccgggtata tgtatcacaa cttactggat
     6001 aaggaccgtc cgttcggcat ggttttcgct accgtagcga ttccgatcag tgattggtgg
     6061 ggcggctcgc acgccatccg gaagcaaaag cttcaggtga aggcggccga gtattcccgc
     6121 caaaacgcca atgagcttct gttggtacaa atgcggaagc tttggaacga gctggaggag
     6181 tcttataagc aagtcaagct ctcggaggag tccatagcga cagccgagga gaatgtccgc
     6241 cttaatacgg actattataa ggcgggcacg gtaacgctga gcgatcttct ggacgcccaa
     6301 tcgctcctcc agcaaagccg tgaccagtat acgggtgatt atacggctta tttgatcaaa
     6361 cgtacggaat atttacaggc gacagggcgt taatttattt ttttttccat atatttgctt
     6421 attaacaaat aataaaacga gaagtgatga tgagctacgc caattatctt tacatagcga
     6481 tccgtgccgc ggtagacgca ggcaagtcga tcatggatat ttataacgac cccgaatcag
     6541 acttcgggat agagagaaaa gcagacaact cgccgttgac aaaggcggat aaggcggccc
     6601 atcgattgat aacaaacgct ttgtccgtta ccccgtttcc ggtcttaagc gaggaaggaa
     6661 aggagatccc gttcaaggag cgctccaaat gggagacgct gtggatcgtg gacccgctgg
     6721 acggtaccaa ggagtttatc aagaaaaacg gcgagtttac cgtgaatatc gccttggtgg
     6781 agaaaggtgt gcccgtgttg ggcgtcattt atgtgcccgt ccggaaggag ttgtatttcg
     6841 cctcctcctc tgtgggtgct tataagttta cgggaatcga tagcagtagc cagccctcga
     6901 tggacgagat gaagcagggg gcgatacatt tgccgatggc gctggcgcat cagggaatcg
     6961 tggtagtggc atcccggtct caccaaacgg aggagaccac cgctttcatc gataatctcc
     7021 gcaagcaggg aaagcctgtt acgttgatca gtagcggtag cagcttgaag atttgtctgg
     7081 tagcggaagg ctcggccgat atctatcccc gtttcgcccc gacgatggaa tgggataccg
     7141 ccgccggcca cgccatcgcc aagtctgccg gttgcgacat atatcatatc gacggtaaga
     7201 ccccgcttcg ctataacaag gaagatttgc ataatccgtg gtttatcgtg aagtgagggg
     7261 gatgtgtatt ttaagttact gtcagcggtg ggagacggag catgctccgt ctctacaagc
     7321 cgtacaatgc attcttgttt atttggttat gaacgaaatt tagaagacta ccttgtaaga
     7381 atataagttg gcccagaatc aatcattatt ggtctatatc ccatataatc ctaaaaatag
     7441 gttagcgaaa ggagtgcgca cttgagtatt cttattattt ttgcgctctt aaaagtaaat
     7501 agatgaattt tgatatagtg tttgtgttgc tggccctgat cggcatgatc gccgccttgg
     7561 tatgggataa gatgcggccg ggaatggttc ttctgacagt ggtcgtgttt tttctctgcg
     7621 taggcattct tactcccaag gagatgctgg agggctttag caataaaggg atgataaccg
     7681 tagccatgct cttccttgtc agtgagggag tgcggcagag cggggcttta ggccaattga
     7741 tcaagaaact gcttcccgag gggaagacca ccgtcttcaa ggcgcaggcg aggatgctcc
     7801 cgcccgtggc tttcgtgtcg gcgttcctga ataatacgcc ggtggtggtt atttttgccc
     7861 cgatcatcaa gcgatgggcg gaggcggtga ggcttccggc cacgaaattc ttgatccctc
     7921 tctcgtatgt cacgatattg ggcggtatat gtaccttgat cggtacttct acgaatctgg
     7981 tggtgcacgg catgattctg gaggcgggat atgagggctt tacgatgttt gagctgggga
     8041 aagtcggtat ttttatcgct atcgccggta ttttatattt gttcgctttc tcgaataaac
     8101 tgcttccgga ctcgaggacg gatacggtat ccgaagacgg ggaggatgag aatcccggga
     8161 atttccaccg ggtggaggcc gtgctgggcg cacgcttccc gggtatcaac aagaccttgg
     8221 gagagtttaa ctttacccgc cattacgggg cgatcgtgaa agaggtgaaa agcggcggac
     8281 agcgttttac ccgtaatctg gatacggtgg tgttgcatga gggcgatacc ttggtgttgt
     8341 gggcggacga ttcttttatc cctacatggg gtgagtctag tgtcttcttg atgttggcga
     8401 atggtaatga ggcaacggag ccggtatcga ggaagaaacg ttggctggct ttaggactgt
     8461 tgatctttat gattacgggg gcgacggtag gagagttgcc agtcgtgaaa gaggccgttc
     8521 caagtatgcg cttggatatg ttcttctttg tctgcattac gacaatcatc atggcgtgga
     8581 ctaagatctt cccgccgaag aaatacacga aatacatctc ttgggatatc ttgataacga
     8641 tcgcttgtgc cttcgctatc agcaaggcca tggagaattc cggctttgcc tccatgatag
     8701 cccgccatat aattagtatg gccgacgatt taggaccgta tgcgttgctg gcgattatat
     8761 ttattattac caatatattt acggagttga tcacgaacaa cgccgcggcg gcattgagtt
     8821 tcccgatcgc cttgtcggtg gctacgcaat taggcgttga tccgacccca ttctttgtcg
     8881 tgatctgtat ggcggcgtcg gctagtttca gtacgccgat cggctaccag accaacctga
     8941 tcgtacaagg cgtgggaggc tataagttca cggatttcgt gaaggtgggc ctgcccttga
     9001 acttgatcac gttcttgatc tccgtgtttg taatacctat gatatggaag ttttagaaaa
     9061 taatatctat ccgattttcg accgtatgct gggtcgtgag gataaagagg cgcttttggg
     9121 gcaaaggggc gtgatggtgt ggttcacggg tttgagtggc tcggggaaaa gcacgatcgc
     9181 tatcgctttg gagcgtgagt tgcataaacg gggattgctt tgccgcatcc tcgacggaga
     9241 taatatccgt agtggtatca acaataatct cgggttctcg ccggaggacc gggtggagaa
     9301 tatacgccgg atcgccgagg tgggtaaact gtttgtcgat acgggtgtta taaccatagc
     9361 ggcttttatc agcccgaaca acgagttgag agagatggcg tccgctatca tcggtaaagc
     9421 ggatttcttg gaggtttacg taagtacgcc gctcgccgag tgcgaacgcc gtgacgtgaa
     9481 aggcctgtat gccaaggccc ggaaaggcga gatcaaggag tttaccgggg tttccgcccc
     9541 gttcgaggca ccggagcgtc cggacctgtc cttggatacc tccgtattga gcgtggagca
     9601 atccgtgaac cggttgttgg agttgatcgt accgaaagta gaaattaaac actgaaaaaa
     9661 gatatgtctg attacaagtt aagtcattta caggagctgg aggccgagtc tatccacatc
     9721 atccgtgagg tagccgccga gttcgagaat cctgttatgc tttattccat cgggaaggat
     9781 tcttccgtga tggtccgttt ggccgagaag gctttcgctc cgggtaaggt tcctttcccg
     9841 ttgatgcaca tcgattcgaa atggaagttt aaggagatga tagagttccg tgattcttac
     9901 gcgaagaaat tcggctggaa cttgatcgtg gagtctaata tggaggcttt ccatgcgggc
     9961 gtgggcccgt tcacgcatgg aagcaaggtg catacggact tgatgaagac gcaggctttg
    10021 cttcatgcct tggataaata taagttcgac gccgctttcg gcggcgctcg ccgtgacgag
    10081 gagaagagcc gtgcgaagga acgtatcttc tcgttccgcg ataagttcca tcaatgggac
    10141 ccgaagaacc agcgcccgga gttgtgggat atctataacg cccgtgtgca taagggcgag
    10201 agcatccgtg tatttccgct atcgaactgg acggagctgg atatctggca atatatccgt
    10261 ctggagaata tcccgatcgt tcccttgtat ttcgccaagg agcgtccgtg cgtggagatt
    10321 gacggtaatt tgatcatggc ggacgacgac cgcttgccgg agcaataccg ggaccagatc
    10381 cgtatgcgta tggtccgttt ccgtacgttg ggctgctggc cgctgaccgg cgccgtggag
    10441 agcgaggcgg atacgatcga gaaaatcgtg gaggagatga tgaccacgac gaagagcgag
    10501 cgtacgaccc gtgtgatcga cttcgatcaa gacgctagta tggagcagaa gaaacgggaa
    10561 gggtattttt aacacagaag agacatggca gatacaaaat taaatataaa ggaattccta
    10621 gataaggacg agcagaagga cctgctgaga ttcttgaccg ccggctcggt ggatgatggc
    10681 aaatcgacct tgataggccg attgctgttt gatagtaaga aaatatacga ggatcagttg
    10741 gatgccttgg agcgtgacag caagcgtatg ggcaacgccg gcgagcatat cgactacgct
    10801 ttgttgctgg atggcttgaa ggccgagcgt gagcaaggta tcacgatcga tgtggcttac
    10861 cgttatttca gcacgaacaa ccgtaagttc atcatcgccg acaccccggg gcacgagcag
    10921 tacacccgga atatgatcac gggtggttcc acggcgaatc tggcgatcat cttggtggat
    10981 gcccgtacgg gcgtgatcac gcaaacctgc cgtcacacct atctggtatc tttgctgggg
    11041 atcaagcatg tggtactggc cgtgaataag atggacttgg tggacttcga caaggatacg
    11101 ttcgaccgga tcgtggcgga ttataaacgt ttcgtggagc cgctggatat cccggatatc
    11161 acgtatatcc ccttatcggc cttggatggc gataacgtgg tggagaagag tgatcgcacg
    11221 ccttggtacg agggtacgtc tttattggat tatctggaga acgtgcctat cgacttggat
    11281 cgtaactacg aggacttccg ttatccggtg caatacgtgt tgcgcccgaa tctggatttc
    11341 cgtgggttta gcggcaaggt ggccagcggt atcgtgcgta agggagatac ggtgatggcg
    11401 ttgccttccg ggaagacctc gaaggtaaag agcatcgtca cctacgaggg tgagttggag
    11461 caggctttcc ctcctcaatg tattacgatc accttggagg acgagatcga tatctcccgt
    11521 ggggagatgc tggtgcaccc ggataacttg ccgatccgcg accgtaattt cgaggccatg
    11581 ctggtgtgga tggatgagga agccatggac gtgaacaagc agttctacat caagcagacc
    11641 actcatacga cacgtgcccg tgtggatagt atccgctata aggtgaacgt gaacacgatg
    11701 gagcaatctt ccgtggatca tctggagctg aacgagatcg gccgtgtggt atttactacc
    11761 ggcaaggagt tgttcttcga tccgtatagg aggaataagc agaccggctc gtttatcttg
    11821 atcgatccga ttacgaataa tacgtccgcc gtgggtatga tcatcgaccg tgtggacgct
    11881 aaagatatgg tgacggaaga cgctttggct accttgaacc tcccggagat gggaatcgga
    11941 gaggagcatt atgaggcgat ccgtaaggtt tgtgaggagt tgggccggca gggcgtatct
    12001 gtgaaatgta taacggaaaa acgataggat atgggattgt tggagtttga taagctaccg
    12061 atcaatacgt tggtcggggc ggattgggat acgttcagga aggtgacggc ccggcagcag
    12121 atagacaagg gctttaaggg taagtatcgc cttacgaccg gtgtttgccg cctgttgagc
    12181 gccttgaagc cgatcgagga tagccggttc aagaaattgg ccgataagcc gctcgagatg
    12241 gaccccttgt ttatcttggg gcattggcgg agtggtacga cttttgttca taacatcttc
    12301 gcctgcgata agcatttcgg ttataccacg acgtaccaga cggtattccc gcacctgatg
    12361 ctctgggggc agcctttctt caagaagaac atggctttct tgatgccgga taagcgtccg
    12421 accgataata tggagttgaa ggtggatctt ccgcaagagg aggagttcgc cttgtcgaac
    12481 atgatgcctt atacatatta taatttctgg ttcttcccga aacgctggat ggagtattgc
    12541 gatcgttact tattgtttaa cgatatcacg gaggaggagc ggcggatctt catggatact
    12601 ttcatgcgtc tggttaaggt ttccctctgg aatacgaacg gtacgcagta tttgagcaag
    12661 aacccaccgc atacggggcg tgtgaagaca ttgctggaga tgttcccgaa cgctaagttc
    12721 atctacttga agcgaaatcc gtatacggta ttcgagagta cccgcagttt ctttacgaat
    12781 acgatccagc cattgcgttt gcaggatatc acgaacgagc agatcgaggc gaacttcatc
    12841 gaggtatatc gccgtctttt ctacaagtac gaggaagaga agcacctgat accggaaggc
    12901 aatctggtgg aagtgaagtt cgaggatttc gagaaagacg ctttcgccat gacggaaaat
    12961 atttacgggt cattaaactt acccggcttt aaggagtcta aggcggatat agagaagtat
    13021 ctgggcaaga agaagggcta caagaagaac caatacaagt acgaggatcg tacggtccgg
    13081 ctcgtagagg aaaattgggg catggccttg aaggaatggg gctatagctt ataaataaaa
    13141 gggttagata ggtattaaat tgatagaggg atgggtttga gtttaagaaa gaaagcgtta
    13201 tttttggcaa tcgcttgtat gcctttgtcc gtggttctcg cggacgggga tggggtgaca
    13261 tcggagaatg tggtgccctt cgcttatgga gacatggata attggattgt ccgtgagatt
    13321 catgagtctg gcattatcgg gggaaatacg aaatggcttt atgagctggg gccctcggat
    13381 acgattgtcg gtaatacggc gtttcgtaat atgggcggtt ctccgtgggc tacttccaac
    13441 gtgatggcga aagtggcggg agtggtgaaa accaatacgt ctgttttccc ggagaaacgg
    13501 ggggatggga tgtgcgcccg catggagacc cgttatgaga gcgtgaaggt tttcggtttg
    13561 gtggatatcg aggtgatcgc cgccggctcc gttttcttgg gtacggtgca tgagccgatc
    13621 aagggaacaa aaaaccctca agcgatgtta caatcaggag tgcctttctc caagaagccg
    13681 aaagcgttgc ggtttgatta taaggtgaaa gccgctcccg agaagaatcg ggtacgtagt
    13741 acggggttca gccgtaagag tacggtggcc gggcaggatt ccttggcggt gatcttgttg
    13801 ttgcagaaac gatgggaaga cgcggaaggg aatgtttatt ccaagcgggt cggtacgatg
    13861 gtgcaacgct atacggaatc tacccctgat tgggtaaatg acgctactta cccgatcctt
    13921 tatggaaata taacatccaa acccgaatat aaaccgtata tgcgtataca agtagaggaa
    13981 cgttatacgt taaatagtaa aggaaaaagc gttcctatcc aagaggtagg ctgggcggag
    14041 ccgggcgagg cacctacgca tatggtgttg cagttcacct ccagccacgg aggggcctat
    14101 atcggctctc cgggaaatac gttttggata gacaacgtag aattaatata ctaatatggt
    14161 cgaagcaaag ataaaagccc tgcgtgatga gctggagcgg cataattata attattatgt
    14221 gctttcggca ccgacaatat cagactttga gtttgataag atgatgaaag agttgcagga
    14281 actggaggcg gcgcatcccg agttcgccga tcc
//
LOCUS       DBMDTB010000099        13940 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_1356_length_13940_cov_12.280223, whole genome shotgun
            sequence.
ACCESSION   DBMDTB010000099 DBMDTB010000000
VERSION     DBMDTB010000099.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 13940)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 13940)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13940
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1356_length_13940_cov_12.280223"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(85..1578)
                     /locus_tag="ACZPB4_13705"
     CDS             complement(85..1578)
                     /locus_tag="ACZPB4_13705"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HIR1099305.1"
                     /translation="MKSKKTVFLTGATGTMGHAGLVELSKRLDRFNITLLARPSKINK
                     EKLAAYEAMAGIRIVWGDLTNYQDVLNGVMGADYVLHVGGMVSPAADYFPKKTLKVNT
                     TAAQYIVDAVKAQPNSDRIKVVYIGSVAQTGHRNAPVHWGRTGDPINISVYDHYAISK
                     TIAERIFVESGIKHWACLRQTGILCPELLFKGSDPITFHVPLDGVLEWATAEDSGRLL
                     ANVCEEEVPDEFWNRFYNISSGPSFRLTNYEFESKLLKAIGCPAPEKIFEPNWFAIRN
                     FHGQWYTDSDLLEGYLHFRSNQTCDNYFKWMASQVPWYFHLAKIVPPVFIKLGMGAIA
                     KKPGLGTRNWIKNRHQDRISAYFGSYEDWQAIPGWDKIRTERPSETPVFLDHGYDESK
                     PKSEWDIEDMRKAAEFRGGKCLSPVMTKGDLSTPLDWECQFGHRFKASPTLVLLGGHW
                     CPECLPLPWNYDEIAKGNPFFAQVWYPFHDKKEHNVYDESIFTDFKE"
     gene            complement(1673..1744)
                     /locus_tag="ACZPB4_13710"
     tRNA            complement(1673..1744)
                     /locus_tag="ACZPB4_13710"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1709..1711),aa:Glu,seq:ctc)
     gene            2016..3875
                     /gene="mutA"
                     /locus_tag="ACZPB4_13715"
     CDS             2016..3875
                     /gene="mutA"
                     /locus_tag="ACZPB4_13715"
                     /EC_number="5.4.99.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004494 - methylmalonyl-CoA mutase
                     activity [Evidence IEA];
                     GO_process: GO:0019652 - lactate fermentation to
                     propionate and acetate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylmalonyl-CoA mutase small subunit"
                     /protein_id="HIR1099306.1"
                     /translation="MAELKEKLFSEFAPVSTEEWMAKITADLKGVPFEKKLVWKTGEG
                     FNVNPFYRAEDIEGLKTTESLPGEFPYVRGTKKDNDWKVRQNIEVCCFKGANEKALDL
                     LTKGVTSLGFIIKGDEVNEENIATLLEGICPASVELNFNTCNCKAEKLIGILADYFKG
                     KGVDAEKCYGSVNYDAFKKPLVKGKENSEWVEGAAAVLKAGQALPNYRVLAVNAFLFN
                     NAGAYISQELGYALAWGNELMAKLTEAGFTADEVAKKIKFNFGISSNYFMEIAKFRAA
                     RWLWAEIVAAYKPACECACKMVAHAQTSEWNMTVYDAHVNLLRSQTEAMSAALAGVDS
                     ITVRPFDKIYQTPDDFSERIARNQQLLLKEECHLDKVVDPSAGSYYVEVLTNSLADVA
                     WKLFLEVEEKGGFSVAVNAGEIQNAVNASNVARKKAVATRREILLGSNQYPNFTEVAA
                     DKIQEKGSCCCGGGHCGEATIPALDFSRGASEFEALRMTTEKSGKTPKVFMLTIGNLA
                     MRLARSQFSANFFGCAGYKIIDNLGFDTVEAGVEAAVKAGAEIVVLCSSDDEYAEFAP
                     AAYKALAGRAEFVVAGAPACADDLKAQGIDQFVNVKSNVLETLKAFNAKLGIA"
     gene            3888..6035
                     /gene="scpA"
                     /locus_tag="ACZPB4_13720"
     CDS             3888..6035
                     /gene="scpA"
                     /locus_tag="ACZPB4_13720"
                     /EC_number="5.4.99.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004494 - methylmalonyl-CoA mutase
                     activity [Evidence IEA];
                     GO_function: GO:0031419 - cobalamin binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylmalonyl-CoA mutase"
                     /protein_id="HIR1099307.1"
                     /translation="MRPNFKNIDIKNAGFAATNAAEWAKANGIEPNWKTPEHIEVKPV
                     YTKEDLEGMEHLNYASGLPPYLRGPYSGMYAMRPWTIRQYAGFSTAEESNAFYRRNLA
                     SGQKGLSVAFDLPTHRGYDADNERVVGDVGKAGVSICSLENMKVLFDGIPLNKMSVSM
                     TMNGGVLPVLAFYINAGLEQGAKLEEMAGTIQNDILKEFMVRNTYIYPPEFSMKIIAD
                     IFEYTSQKMPKFNSISISGYHMQEAGATADIEMAYTLCDGMEYLRAGINAGIDVDAFA
                     PRLSFFWAIGVNHFMEIAKMRAARMLWAKIVKSFGAKNPKSLALRTHSQTSGWSLTEQ
                     DPFNNVGRTCIEAMAATLGHTQSLHTNALDEAIALPTDFSARIARNTQIYIQEETKIC
                     KEIDPWAGSYYVESLTNELVHKGWALIQEIESMGGMAKAIETGLPKMRIEEAAARTQA
                     RIDSGVQTIVGVNKYRLPKEDPIDILEIDNTAVRNEQIAALKELRANRDEAAVQKALA
                     DITECVKTKKGNLLELAVKAAGLRASLGEISDACEVVVGRYKAIIRTISGVYSSETKK
                     DADFQKACELCEQFAKKEGRQPRIMIAKMGQDGHDRGAKVVATGYADCGFDVDMGPLF
                     QTPAEAARQAVENDVHVMGVSSLAAGHKTLVPQVIEELKKLGREDIIVIAGGVIPAQD
                     YDFLYKAGVAAIFGPGTSVSKAACQILEILLGE"
     gene            6165..7019
                     /gene="coaW"
                     /locus_tag="ACZPB4_13725"
     CDS             6165..7019
                     /gene="coaW"
                     /locus_tag="ACZPB4_13725"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004594 - pantothenate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II pantothenate kinase"
                     /protein_id="HIR1099308.1"
                     /translation="MGIVIGIDVGGSTTKIVGVEDKKIKNPMFVKATDPVTSLFGAFG
                     KYIYDNNISLSNIEKVILTGVGSAYIDQPLYGLPTAKTDEFLANGLGAQYNTGLDSLL
                     VVSMGTGTSFVKVQGSTIEHIGGLGIGGGTILGLSKLLLKTHDFHQIASLAEHGSLND
                     IDLHIRDITPHPLPGLPLDVTASIFGKADANAKVEDIALGIVHMVLQTIGQGAVFASL
                     NGDIKNIVLIGNLTRLPQCPDIFPRLEEMCDVHFKIPEYAEYRTAIGAALCYIRNREY
                     KDIFCGKC"
     regulatory      7039..7241
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            7534..8142
                     /locus_tag="ACZPB4_13730"
     CDS             7534..8142
                     /locus_tag="ACZPB4_13730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0015288 - porin activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="porin family protein"
                     /protein_id="HIR1099309.1"
                     /translation="MKKIVGLVMVALLALMALPANAQLKFGIKGGVNISSVHFNSDVL
                     KADNVTGFQVGPMIETTLPLVGVGIDAAVLYSQKGLETTSAGGVKTSMKTDYIDVPVN
                     LKWKFGLPIVKAYLAAGPYIGFRVGGDKFWDIPGSVADQVKAKNFSAGLNFGAGVELI
                     SHLQVGFNYGLGLTDNYSIEKVNLSDGAGKNRGWSITAAILF"
     gene            8230..10692
                     /gene="priA"
                     /locus_tag="ACZPB4_13735"
     CDS             8230..10692
                     /gene="priA"
                     /locus_tag="ACZPB4_13735"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication restart helicase PriA"
                     /protein_id="HIR1099310.1"
                     /translation="MKYADVILPLPLENSYTYRIPEDLERAVTPGCRVIVHFGKKRYY
                     TAIVMEVHDREPVSDFETKEIYALLDATPVLRRPQLRFWKWISSYYICKLGDVYKAAL
                     PSGLKLESETAVTYNEDFEATAPLRPNEQAVLDAFSGVLKLTISELEKKTGLRNVVPI
                     VSSLMVKGAVEVSEELKRGFVPKTQAFIRLAEAYRDETKLQAVFEDLKRAKKQELLLV
                     SFLDLSHTLNPALSKELSKKELLERSGYTSAVLEGLLKRGILESYEKEVGRLQVSVCR
                     LQEPNPLSPAQEKAYGEIHEAFKTKEVCLLHGVTSSGKTEIYVRLIHEVLRLGRQVLY
                     MLPEIAITTQITERLAKLFGDKLLVYHSKFSDNERVEVWNKLLHNDEPMLVLGVRSSL
                     FLPFKDLGLIIVDEEHENTYKQQDPAPRYHARNAAIVLAGMHGGKTLLGSATPSIDSY
                     FNATAGKYGLVELSTRYGDCLMPEIITVDVKELKRKKIMKDTLFSPQLVEKVREALSR
                     GEQAILFQNRRGFAPMIECRGCGWVPRCVNCDVSLTYHKAHNQLVCHYCGYTYRLPQV
                     CPECKGTEFKMQGFGTEKVEEEIAGQFPAVKVERLDFDTARTRTAYERIISDFEKGKT
                     QILIGTQMLSKGLDFGNVSVVGILSADSLMNFPDFRAHERAYQLMVQVSGRAGRRDKR
                     GTVILQTTQPEHPLIRMVQHFAYKEMVSLQLSERSMFRYPPYYRLIVLILRSRNEEAL
                     QEMSALYAEKLRARLGERVLGPVTPPITRVQTLHIKKIVLKIEISAGIAPLREILEGI
                     HAEMQGYVPFKQLLVHYDVDPA"
     gene            10720..>11207
                     /locus_tag="ACZPB4_13740"
     CDS             10720..>11207
                     /locus_tag="ACZPB4_13740"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase"
                     /protein_id="HIR1099311.1"
                     /translation="MERSLVMKEEKVRLLFVCLGNICRSPSAEAVMKRLVKDAGLGDR
                     IEIDSAGIAGYHEGDRADSRMRAHAARRGYVLDSISRPVRQWDFHDFDLIIGMDDQNI
                     TDLKRMAPDLESVAKIHQMTEFSRNKLYDHVPDPYYSGAEGFELVLDLLEDACAGLLE
                     YC"
     assembly_gap    11208..11307
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(11361..13496)
                     /locus_tag="ACZPB4_13745"
     CDS             complement(11361..13496)
                     /locus_tag="ACZPB4_13745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="T9SS type A sorting domain-containing protein"
                     /protein_id="HIR1099312.1"
                     /translation="MRTFRYILSLLAATLALLAQPAMAQAPETSTKAQPSDPVFPYLL
                     TIQQPAEGATLDVMIMNAAGTYTAVSSGQTVYNGTKVDLFFAPQEGYRLTEGSITYNG
                     NATTAEPLAPNDKGYTAQRSFTMPAQPVTVTAEAELIRYTITYDPAGGTLPQGSPTQY
                     TIVSDDLTLPTPTHANTYLSFEGWKDADGNTVATVAKGSTCDLSLTAQWKESELAEVV
                     GGPDETRIVTTIMTAEEILAALAATWPKFTFTTDRGDVIDSPISWKLKDGATLDLTPG
                     KKNPFIWTATPLPDGVKGNGYVMSGTTQVYLEASPIIPKDNGEITITDENKFQQDGGT
                     DNYFNGEINGEEGKTINKLTLTPPADTDMTIKLNEVTSATTLINGTGKTNLTLNGTNS
                     LGAVTIEPGNELTLTPGENAGDLVNTAVTNKGHFTDLTARVPTVTLPGNITLERVDPA
                     ASTPIPSTDGYAELEAGITAPEGTQMNLTYLWQIFNAQAGTWSTAPDDSQLRNASNTY
                     RTRTVGQYRCLVTATVTGDGGTTTTTALATPPAAVTSYVPPITPQPATYTVTLPSLVG
                     ASTTPAAGAHTVTEGDGFSFTLTLDADYDQSVPVVTVNGNALTPDASGKYTIADISAN
                     LTVAITGIVRNTTTGIEQVENATLIRAESGALLIRTPVSVTAQVIALTGNVVRTVRLP
                     AGDSRVDGLASGIYIVRLSNEITKKVIIR"
     gene            complement(13536..>13940)
                     /locus_tag="ACZPB4_13750"
     CDS             complement(13536..>13940)
                     /locus_tag="ACZPB4_13750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099313.1"
                     /translation="FKGNRASYNVEMRNIYVLSDDGSRFELKDRVTLRPFESYVVANA
                     ATQALLKSLRLDGIVTGTELAEIPADNSFRAWTADGRLHLSADHAEKVAVYHVSGTLK
                     CYLPLLRGETTIALPSGIYLVRQGGTAIKVVL"
BASE COUNT         3222 a         3005 c         3935 g         3678 t
ORIGIN      
        1 tgttataaca gataatatcc ggtaaaagta tgttgcgttg agataaataa tctaaaaaac
       61 aaaaatctct tgatgcgttg aattttattc cttgaagtca gtgaatatgg attcatcata
      121 tacattgtgt tcctttttat cgtggaatgg ataccatact tgggcaaaga acggatttcc
      181 tttagcgatc tcgtcgtaat tccaagggag aggtaaacat tccgggcacc aatggcctcc
      241 taataatact aatgtgggag aggccttaaa acggtgaccg aattggcatt cccaatcgag
      301 tggagtcgat aaatctcctt ttgtcatgac cggtgacaag cattttcctc ccctgaattc
      361 cgcggcttta cgcatatcct cgatatccca ttccgattta ggcttacttt catcatagcc
      421 atgatccaga aagacgggtg tttcggaggg gcgttctgtc cggatcttat cccaacccgg
      481 gattgcttgc caatcctcat acgagccaaa atatgcggat atacgatctt ggtgtctgtt
      541 cttgatccag ttacgagttc ccagtcccgg ctttttagcg atggctccca tacccagttt
      601 tatgaagaca ggagggacga tctttgctag gtggaaatac caagggactt ggctggccat
      661 ccatttaaaa taattgtcgc aagtttggtt actgcggaaa tgcagatatc cttccaatag
      721 atctgaatcg gtataccatt gtccgtggaa attacggata gcgaaccagt tcggttcgaa
      781 tattttctct ggggcgggac aaccaatcgc ttttaacaat ttactctcaa actcataatt
      841 cgtcaggcgg aaagacgggc cgctactaat attatagaaa cggttccaaa actcatccgg
      901 cacctcctcc tcgcatacat tcgctagtaa gcgaccggaa tcctcggcgg tagcccattc
      961 cagcacgccg tctagcggta cgtggaatgt gattgggtcc gaacccttga ataataattc
     1021 ggggcataag ataccggttt ggcgaaggca cgcccaatgt ttaatacccg actccacgaa
     1081 aatacgttcg gctattgtct ttgagatggc ataatgatca tagacactta tattgatcgg
     1141 atctcccgta cgtccccaat gaacaggtgc gttacggtgg ccggtttgcg ccacggagcc
     1201 gatatagact accttgatcc ggtctgagtt cggttgtgct tttacggcat ccacgatata
     1261 ttgggcggcg gtcgtgttta ctttcaaggt ttttttaggg aaataatccg ctgccgggga
     1321 aaccattcca cctacatgca atacgtagtc cgcccccatt actccattta agacatcttg
     1381 ataatttgtc aagtctcccc aaacgatacg gatccctgcc atggcctcat atgcggctaa
     1441 tttctcttta ttgattttgc ttggacgagc caaaagtgtt atattaaaac gatctagccg
     1501 cttggacaac tcgaccaatc cggcatgccc catcgtcccg gtggctccgg tcagaaagac
     1561 ggtcttttta cttttcatga tataatttag tgtataataa aagacttagg atactatcgg
     1621 gtagcgaagg tatataaaaa aaaactccca accaatagat tgagagcttt tgtagtggat
     1681 acgagaatcg aactcgtatt acatgcgtga gaggcatgtg tcctaaccgt tagacgaatc
     1741 caccatttag gtgtcattgt ttttgtttga cgatgcaaag gtagatatat tttttaattc
     1801 tgcaatagtt gaaccgagtt tttttgaaga aaaagtgtgt tttttatcaa aatgccaaga
     1861 aaacggggag aataccacta aaaggcgtta aaagtagttg cgatttcatt gttttttcat
     1921 tgtcggtact gtttatttat tctacctttg ccatctgtaa ttgaacaaaa tagtattgaa
     1981 cattactaat accagtttaa taaacaacta atattatggc agaacttaaa gaaaaacttt
     2041 tctcagaatt cgctcctgtg tctactgaag agtggatggc gaagataacg gccgacctga
     2101 aaggggtacc gtttgagaaa aagcttgttt ggaagacagg cgaaggattt aatgtaaatc
     2161 ctttctatcg tgcagaagac atcgagggtt taaagactac agagtctctt cccggtgaat
     2221 tcccttatgt tcgtggaacg aagaaagaca acgattggaa ggtacgccag aacattgaag
     2281 tttgctgctt caagggtgct aacgagaaag cacttgacct tttgacgaaa ggtgttactt
     2341 ctcttgggtt catcatcaaa ggtgatgagg tgaacgagga gaatatagct actttattag
     2401 aaggtatttg tccggcttcc gtagaattga acttcaacac ttgcaactgc aaagcggaga
     2461 agttgatcgg tatcttggct gactacttca aaggcaaggg tgtcgacgca gagaagtgct
     2521 acggttctgt aaactatgac gctttcaaga aacctttagt aaaaggtaaa gaaaacagtg
     2581 agtgggtaga aggtgccgca gctgtgctca aagctggaca ggctttgcct aactaccgtg
     2641 tattggctgt aaatgcgttc cttttcaaca atgctggcgc ttacatttct caggaattag
     2701 gttacgcctt ggcttggggt aacgaattga tggcaaaact taccgaggct ggtttcaccg
     2761 ctgacgaggt tgccaagaaa atcaaattca attttggtat cagctctaac tacttcatgg
     2821 aaatcgctaa gttccgtgcg gctcgttggt tgtgggccga gatcgtagcc gcttataagc
     2881 cggcctgcga atgcgcttgc aagatggttg ctcacgcaca gacttcagag tggaacatga
     2941 cggtttacga tgctcacgta aacttgcttc gttctcaaac tgaggctatg tctgccgctc
     3001 ttgccggcgt agactctatc acggttcgcc cgtttgataa gatttaccag actccagacg
     3061 atttctctga gcgtatcgca cgtaaccaac aattattatt gaaggaagag tgccacttgg
     3121 ataaggtcgt tgacccgtct gccggttctt attatgtaga ggtattgacg aattccttgg
     3181 ctgatgtcgc ttggaagttg ttcttggagg ttgaggaaaa aggaggattc tccgttgccg
     3241 tgaacgcagg tgagatccag aatgccgtta acgcttcgaa tgtagctcgt aagaaagcgg
     3301 ttgctacccg tcgtgagatc ttgttgggtt ctaaccagta tcctaacttc acggaagtag
     3361 ctgccgataa gattcaagaa aaaggttctt gctgttgtgg cggtggtcat tgcggtgagg
     3421 caacgatccc ggctctagat ttctctcgcg gcgcttccga attcgaggct ttgcgtatga
     3481 cgacagagaa gagtggcaag actccgaagg tatttatgtt gacgataggt aacttggcga
     3541 tgcgtttggc tcgttcacag ttctccgcta acttcttcgg ttgtgccgga tataagataa
     3601 ttgataactt aggcttcgat acggttgagg ctggtgttga ggctgctgtc aaggctggtg
     3661 ccgagatcgt ggttctttgc tctagtgatg acgagtatgc tgaattcgct cctgccgctt
     3721 acaaggcttt ggccggacgt gccgaattcg ttgtagccgg agctcctgct tgcgcggacg
     3781 acttgaaggc tcaaggtatc gaccagttcg taaatgtaaa gagcaatgtg cttgagacat
     3841 tgaaagcatt caacgctaaa ttaggaatcg cttaagtata aacaattatg agaccaaatt
     3901 ttaaaaacat agatataaag aatgccggat tcgcagctac aaacgctgcc gaatgggcaa
     3961 aagccaatgg catcgagccc aattggaaaa cacccgagca tatcgaggtg aaacctgtat
     4021 atacaaaaga agacttggag ggtatggagc acttgaacta tgcttccggt ttgcctcctt
     4081 atctacgtgg cccgtacagc ggtatgtacg ctatgcgtcc ttggacaatc cgtcagtacg
     4141 caggtttctc taccgctgag gagtctaacg ctttctatcg ccgtaacttg gcttccggtc
     4201 agaaaggttt gtccgttgcg ttcgaccttc cgactcaccg tggttacgat gccgacaacg
     4261 aacgtgtggt tggtgatgta ggtaaagcgg gtgtatctat ctgttccttg gagaacatga
     4321 aagtgttgtt cgatggtatt cctttgaaca agatgtctgt ttccatgacc atgaatggtg
     4381 gtgtgcttcc ggtattggca ttctatatca acgcaggttt ggagcaaggt gctaagttgg
     4441 aggaaatggc cggtacgatc cagaacgata tcttgaaaga gttcatggta cgtaatacct
     4501 atatctatcc gcctgagttc tccatgaaga ttatcgctga tatcttcgag tacacctctc
     4561 agaagatgcc gaagttcaac tctatctcta tctccggtta tcatatgcag gaggctggtg
     4621 ctacggctga tatcgagatg gcttatacgt tgtgcgacgg tatggaatat cttcgtgccg
     4681 gtatcaacgc cggtatcgat gtggatgcgt tcgctccccg tttgtcattc ttctgggcta
     4741 tcggtgtaaa tcacttcatg gagatcgcca agatgcgtgc ggctcgtatg ttgtgggcga
     4801 agatcgtgaa gagcttcggc gctaagaacc cgaaatcatt ggcattgcgt acacatagcc
     4861 agacttccgg ttggtcattg accgagcaag atccgttcaa taacgtagga cgtacttgta
     4921 ttgaggctat ggccgctaca ttaggacata cacaatcttt gcatacgaac gcattggatg
     4981 aggcgatcgc tttgccgacc gacttctctg ctcgtatcgc tcgtaataca cagatttaca
     5041 ttcaggaaga gactaagatc tgtaaggaga tcgacccgtg ggctggttct tactatgtag
     5101 agtctttgac gaatgagttg gtacataaag gttgggcatt gatccaagag atcgagagca
     5161 tgggtggtat ggcgaaagcc atcgagacag gtcttcctaa gatgcgtatc gaggaagctg
     5221 ccgctcgtac acaggctcgt atcgactctg gtgttcagac catcgttggt gttaacaaat
     5281 atcgtttgcc gaaggaagat ccgatcgata tcctagagat cgataataca gctgtacgta
     5341 acgagcagat cgccgctttg aaggagttgc gtgctaaccg tgacgaagcc gctgttcaaa
     5401 aagctttggc tgatatcacg gagtgcgtga agacgaagaa gggcaactta ttagagttgg
     5461 ctgttaaggc tgccggcttg cgtgcgtcat tgggagagat ctccgatgct tgcgaggtgg
     5521 ttgtaggtcg ttataaagca atcattagaa ctatttcagg cgtgtattca tcagaaacta
     5581 agaaagacgc agacttccag aaagcttgcg agctttgcga gcaattcgct aagaaagaag
     5641 gccgtcagcc tcgtatcatg atcgctaaga tgggtcagga cggacacgac cgtggcgcta
     5701 aggttgtcgc tactggttat gcggactgtg gtttcgacgt agatatggga ccgttgttcc
     5761 agactccggc cgaggctgcc cgtcaagctg tggagaacga cgttcacgta atgggcgttt
     5821 cttctttggc cgctggtcat aagacgttgg ttccgcaggt tatcgaggag ttgaagaaac
     5881 taggtcgtga ggacatcatc gttattgctg gaggtgtaat cccggctcaa gactatgatt
     5941 tcttgtataa ggctggcgtt gccgctatct ttggcccggg tacttccgta tcgaaggcag
     6001 cttgccagat ccttgagatc ttgttaggcg aataaataga gtttaggcct tacggttttt
     6061 aaataaagag aggctggaca attgattttg tccggccttt tttagtattg tatgcgggtt
     6121 tatgtacttt tgtagcgatt attcaattaa aaagggaaag aatcatggga atcgttatag
     6181 gtatagatgt gggaggtagc acgaccaaga tcgtcggcgt ggaggataag aagatcaaga
     6241 acccgatgtt cgtgaaagct accgatccgg taacctcttt attcggggcc ttcggtaaat
     6301 atatttatga taataacatc tcgctctcga atatagagaa agtgatcttg acaggtgtag
     6361 gtagcgctta tatcgatcaa cctttatatg gcttaccaac tgcgaagacg gatgagttcc
     6421 ttgcgaatgg gctaggggcg caatataata cgggactgga cagtctattg gtggtcagca
     6481 tgggaacggg tacctccttt gtcaaggtac aaggctccac gatcgagcat atcgggggat
     6541 tgggtatcgg tggcggaaca atcctcggct tgtctaagct attattgaaa acgcatgact
     6601 ttcaccaaat agcgtctttg gccgagcacg gttccttgaa tgatatcgac ttgcatatcc
     6661 gggatattac gccgcatccg ctacccggcc tgccgctgga cgtgacagcc tctattttcg
     6721 gaaaagcgga cgcgaacgct aaggttgagg atatcgctct cggtatcgtt catatggtct
     6781 tgcagaccat cgggcaagga gctgttttcg cctcgttaaa tggcgatatc aagaatatcg
     6841 tattgatcgg taacctaact cgcttgccac aatgcccgga tatttttccc cgtctggagg
     6901 agatgtgcga tgtccatttc aagataccgg agtatgccga atatcgcacg gctatcgggg
     6961 cggctttatg ctatatcagg aaccgggaat ataaggatat tttttgtgga aagtgttagg
     7021 ctacatcaaa actttatgta tctttgctac atgctttgtt ccctttcggc aatcgccgga
     7081 tagggattaa aagggaatcg ggtgagaatc ccggacagtc ccgctgctgt aagcttcata
     7141 aacgggttga gcaatactgt tgccactgtt cattcaagtg aatgggaagg cgcttaagac
     7201 cggaagtaag tcagaagacc tgcaaggcgt gtatattttc gacggcttcg aggaaaggcc
     7261 ggaagagaac gcaagaaccg tatccggttt ttactattct ttatccaagg ttttcttatc
     7321 aagtcgtctc atggtttcgg ataattattt tgccataata attagggaaa gaagcatgaa
     7381 tctgaccgac gggatgagct ccgtgtgtaa gatgcatgct ttctttgcgt ttaaaggact
     7441 ggggtattcc gtgaacactc tatagagaat atttgtttat tattagaaaa gtgcgtttat
     7501 ttgcaacgag taattaacaa aagaagtatg aatatgaaga aaattgtggg acttgttatg
     7561 gttgccttgc tagcgttgat ggcgcttccg gcgaacgctc agcttaaatt cggtatcaag
     7621 ggaggtgtga atatatcgtc tgttcatttc aactcggacg tgttgaaagc ggataacgta
     7681 accggcttcc aagtgggtcc gatgatcgag acgaccttac cgttggtggg tgtcgggatc
     7741 gatgcggcag tgttgtattc gcaaaagggt ttggaaacga cctcggctgg cggggtgaag
     7801 acttcgatga agacggatta tatcgatgtt ccggtcaact tgaaatggaa attcggctta
     7861 ccgatcgtca aggcgtatct ggcagccggt ccgtatatcg gtttccgtgt aggcggtgat
     7921 aagttttggg atatcccggg ttccgtagcg gatcaggtga aggcgaagaa tttcagtgca
     7981 ggtcttaact tcggtgccgg cgtggaactg atcagccact tgcaggtggg tttcaattat
     8041 ggtctgggac tgactgataa ctatagtatt gagaaggtga acctctccga cggtgccgga
     8101 aagaaccgtg gatggtctat cacggcagcg atcttgttct aaataggtga aaataaaatg
     8161 agagaggctg ggctttagaa gtccggcctt ttttgttatt tttgggctcg taatgaaaca
     8221 cctgtttgaa tgaaatacgc ggacgtcata cttccccttc ctttggagaa tagctatacc
     8281 tatcggatac ccgaagatct ggagagagcc gtgactcccg gttgccgggt gatcgtgcat
     8341 ttcgggaaga aacgatatta tacggctatc gtcatggagg tacacgaccg ggaaccggta
     8401 tccgattttg agacgaagga gatctacgct ttgctggatg ccacgccggt gctccgccgt
     8461 ccgcaactcc gtttctggaa atggatatct tcttattata tatgtaagct gggcgacgtg
     8521 tataaggcgg ccttgccttc cggcttaaag ttggaaagcg agacggcggt tacttataat
     8581 gaggatttcg aggccaccgc ccccttgcgc ccgaacgagc aagcggtact ggatgctttt
     8641 agcggggttt tgaaattgac gatctcggag ttggagaaga agaccggtct tcgaaatgtt
     8701 gtcccgatcg tctcttcctt gatggtgaaa ggggcggtcg aggtgagcga ggagctaaag
     8761 cgaggattcg ttcccaagac acaggcgttt atccgtttgg ccgaggctta ccgggatgag
     8821 acgaaattac aggcggtgtt cgaggatttg aaacgagcga agaagcaaga gcttctgctg
     8881 gtcagcttct tggatttaag ccataccttg aatcccgctt tatcgaagga gctttccaag
     8941 aaagagctat tggaacgcag tggttatacc tctgcggtat tggaggggct gctgaaacgg
     9001 ggtatcttgg agagttacga gaaagaggtg ggtcgtttgc aagtatctgt ctgccgcttg
     9061 caagagccga atccgctcag tccggcgcaa gagaaagcct atggagagat ccatgaggct
     9121 ttcaagacga aggaggtctg cttgcttcat ggcgtgactt ccagtggtaa gaccgagata
     9181 tacgtccgtt tgatccatga ggtcttgcgg ctggggcggc aggttttata tatgttgccg
     9241 gagatcgcta tcacgaccca gatcacggaa cggctggcga aattattcgg ggataagcta
     9301 ttggtctacc actctaagtt ctcggataac gagcgggtgg aagtttggaa taagctattg
     9361 cataacgacg agcctatgct ggtattgggg gtccgttcgt ccctcttcct tccgtttaag
     9421 gacttgggct tgattatcgt ggacgaggag catgagaata cgtataagca gcaggacccg
     9481 gcaccccgtt accatgcccg taacgctgcc atcgtcttgg cgggtatgca cggcggtaag
     9541 accttattgg gttccgccac tccctccatc gattcttatt tcaacgctac ggcggggaaa
     9601 tacggtctgg tcgagctatc cacccgctac ggtgattgct tgatgccgga gattattacg
     9661 gtggacgtga aggagctaaa gcgcaagaag atcatgaaag ataccctttt ctcccctcag
     9721 ttggtggaga aggtgcggga ggccctatct cggggcgagc aggcgatcct attccaaaac
     9781 cgccggggat tcgccccgat gattgagtgc cgggggtgcg gatgggtgcc tcgttgcgtg
     9841 aattgcgacg tgagtcttac ctatcacaag gcgcataatc agctggtttg ccattattgc
     9901 ggttatacct accgcttgcc gcaggtatgt ccagagtgta aggggacgga gttcaagatg
     9961 caaggtttcg gtacagagaa ggtagaggag gagatcgctg ggcaattccc agcggtgaag
    10021 gtggagcggc tggatttcga tacggcccgt acccgcacgg cttacgagcg gatcatctcg
    10081 gatttcgaga aggggaagac acaaatcttg attggtaccc agatgttgtc gaagggattg
    10141 gatttcggga atgtcagcgt ggtcggaatc ttgagcgccg atagcttgat gaatttcccg
    10201 gacttccggg cgcacgagcg ggcttatcaa ttgatggtac aggttagcgg acgtgccgga
    10261 cgacgggata agcggggtac ggtgatcttg cagactactc agccggagca tccattgatc
    10321 cgtatggtgc agcattttgc ttataaggaa atggtgagct tgcaattgag cgagcgtagt
    10381 atgttccgtt acccgcctta ctaccgtttg atcgtcttga tccttcgaag tcggaatgag
    10441 gaggctttgc aggaaatgtc tgctttatac gccgagaaac ttcgtgctcg tttgggtgag
    10501 cgggtgttgg ggccggttac gccgcctatc actcgggtac agacgcttca tatcaagaag
    10561 atcgtcttga agatcgagat atccgccggg atcgctccgc ttcgtgagat attggagggt
    10621 attcatgcgg agatgcaggg atatgtaccg tttaagcagt tgcttgttca ttatgatgtg
    10681 gacccggctt gagaattgaa aatggagaat tgaaaattaa tggaaaggag cttagtgatg
    10741 aaggaggaga aggtacggtt attgtttgtg tgcttgggga atatatgtcg ctctccgtcg
    10801 gcggaggcag taatgaagag gttggtgaag gatgcgggat tgggagatcg gattgagatc
    10861 gattccgccg ggatagccgg gtatcatgag ggagaccggg cggattcacg gatgcgggcg
    10921 catgcggccc gtaggggata tgtgttggat tcgatctccc gtccggtacg tcagtgggac
    10981 ttccatgact tcgatttgat tatcggcatg gacgaccaaa atataacgga cttgaaacgg
    11041 atggctcccg atctggaatc cgtcgctaag atacatcaga tgacagagtt ctcccggaat
    11101 aagttgtacg atcacgtccc ggatccttat tatagcggtg ccgaaggttt cgagttggtc
    11161 ttggatctat tggaagatgc ttgcgccggg ttgttggaat attgtaannn nnnnnnnnnn
    11221 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    11281 nnnnnnnnnn nnnnnnnnnn nnnnnnnacc tctttttgtg agagcggcga tgacagccgc
    11341 tctcactcgt gaaaccttgc ctatcggatt atcactttct tcgttatctc attggatagg
    11401 cggacgatat agataccgct agccaagcca tctacacgac tgtctccggc gggaagccgt
    11461 accgtgcgga ctacgtttcc ggtgagggcg atcacctgcg ctgtcacgga gactggcgta
    11521 cggatcagca aggctccgct ctcggcacgg atcaaggtag cgttttccac ttgctcgata
    11581 ccggttgtgg tatttctcac gataccggtg atcgctacgg tcaggttggc ggaaatatcg
    11641 gcgatcgtgt acttgccgct tgcgtcgggg gtgagggcgt ttccgttcac ggtcactacg
    11701 gggacggact ggtcatagtc tgcgtccaag gtgagggtga aggagaagcc gtcgccttcg
    11761 gttaccgtat gcgctccggc tgccggggtg gtggaggctc ctaccaagga ggggagggtt
    11821 acggtatagg tagcgggctg tggcgttatg ggaggaacgt aagacgttac ggcagccggg
    11881 ggcgtggcga gcgctgtggt cgtggtcgtg ccgccgtctc cggttacggt ggcggtaact
    11941 aggcaacgat actggcctac ggttctcgtc ctgtaggtat tcgaggcgtt gcgcagctgc
    12001 gagtcatccg gggcggtaga ccatgtgccg gcctgtgcgt tgaaaatctg ccatagatac
    12061 gtcaaattca tttgggtgcc ttcgggggcg gttatgccgg cctcaagctc cgcgtagccg
    12121 tcagtggatg gtatcggggt gcttgccgcc gggtctaccc gttcgagggt gatgttgccg
    12181 gggagtgtca cggtgggcac tcgtgcggta agatccgtga aatggccctt gttggtgacc
    12241 gcggtgttga caaggtcgcc ggcattctcg ccgggggtga gcgtcaattc gttgccgggc
    12301 tcgatcgtga ccgcacccag actgttcgtg ccgttcaagg tgaggttggt cttcccggtc
    12361 ccgttgatga gggtggtcgc ggaggttacc tcgttgagct ttattgtcat atcggtatcg
    12421 gcgggagggg tgagggtgag tttgtttatg gtcttgccct cctctccgtt gatctctccg
    12481 ttgaagtagt tgtcggtacc accgtcttgt tggaacttgt tctcgtccgt tatcgtgatc
    12541 tcgccgttgt ctttcggtat gataggggag gcttcgaggt agacctgcgt ggtgccggac
    12601 atcacgtacc cattgccttt cacgccatca ggcagcggtg tggctgtcca gatgaagggg
    12661 ttcttcttgc cgggcgtgag gtcgagggta gcgccgtctt tcagtttcca cgagatcggg
    12721 ctatctatca cgtcgcctct gtcggtggtg aaggtgaact tgggccatgt ggcggcaaga
    12781 gcggccagaa tctcttcggc ggtcatgatg gtggtgacga tccgggtctc gtccggccct
    12841 cctaccacct ctgccagctc gctctctttc cattgggcgg tgagggagag atcgcaggtg
    12901 gagcctttcg ccacggtcgc taccgtattc ccgtcggcgt ctttccagcc ctcgaaggag
    12961 aggtaggtat tggcgtgtgt cggcgtaggg agggtgagat cgtccgatac tatggtatat
    13021 tgggtggggc tgccctgcgg gagggtgccg ccggccggat cgtaggtgat cgtgtagcgg
    13081 ataagctcgg cctcggcggt aaccgtcacc ggctgggcgg gcatcgtgaa gctacgctgt
    13141 gcggtgtagc ccttgtcgtt cggtgctagg ggctccgcgg tcgtagcgtt gccgttgtag
    13201 gtgatggagc cttccgtcag tcggtagcct tcctgcgggg cgaagaagag gtctaccttg
    13261 gtcccgttgt agacggtctg gccggaggat acggcggtgt acgtgccggc ggcgttcatg
    13321 atcattacgt ccagcgtcgc tccctcggcg ggttgctgga tggtgaggag gtatgggaag
    13381 actgggtcgg aaggttgcgc cttcgtgctc gtctccgggg cttgcgccat cgccggctgc
    13441 gccagcaggg cgagcgtagc ggctagcaag gataggatat atctgaatgt tctcatattt
    13501 gtatctgttt tagtgtatat aatataatgt atgctctaca ggacgacctt gatcgcggta
    13561 ccgccttggc ggacgagata gatgccggaa ggaagggcga tcgtcgtctc gccgcgcaag
    13621 agcggcagat agcacttcaa ggtcccgctg acgtggtata cggccacctt ctcggcatgg
    13681 tcggcgctaa ggtgcaaacg tccgtcggcg gtccaagcgc ggaagctgtt gtccgccggg
    13741 atctcggcca gctccgtacc cgtgacgata ccgtccaagc ggaggctctt cagcagggct
    13801 tgggtggcgg cattggccac gacatagctc tcaaagggtc gcagggtaac ccggtccttc
    13861 agctcgaagc ggctgccgtc gtcgctgagg acgtatatgt ttcgcatctc cacattgtac
    13921 gaggcccgat tgcccttgaa
//
LOCUS       DBMDTB010000100        13695 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_1381_length_13695_cov_11.803737, whole genome shotgun
            sequence.
ACCESSION   DBMDTB010000100 DBMDTB010000000
VERSION     DBMDTB010000100.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 13695)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 13695)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13695
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1381_length_13695_cov_11.803737"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(7..939)
                     /locus_tag="ACZPB4_13755"
     CDS             complement(7..939)
                     /locus_tag="ACZPB4_13755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009009 - site-specific recombinase
                     activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HIR1099314.1"
                     /translation="MKKEDVVAGMLAYIAHLREVGRYSTAKSYLDALRSFKCFCGMEE
                     IPYAYIDKERLLLYQAWLSKRGCMRNTVSTYMRRIRHIYNLAVEAGEVSYIPNLFKGV
                     FTGVESKRKKALPLDSLRSLMGTPRVEPEMRRTQLCFCLMFSFSGMAFVDFAHLRKEN
                     VKDGVLSYHRQKSGSFIRVEIPADVRLLLDELAVCTDKDSPYLFPFLSGKKTGEAAYA
                     EYNGALLRFNRDLRSLAETCGVGEPVTSYTIRHSFATTLKEQDVPIEMISELLGHTSI
                     KTTQIYLKSFSLERLSAVNRACFESVYKPVSEVG"
     gene            1083..1715
                     /locus_tag="ACZPB4_13760"
     CDS             1083..1715
                     /locus_tag="ACZPB4_13760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011965952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BT4734/BF3469 family protein"
                     /protein_id="HIR1099315.1"
                     /translation="MKNEFKMSLFAAPISPVKDSLTGRVSRPATVYPSREVTLQEVVR
                     LITGDPALERLTRQLRLPLETGDKERFSELKRQTLPYVTPCGTFSYRKSDRLLAPSGL
                     VVVDVDGLDSTAEAEALRRQLFDDAYLCPALCFISPSERGVKAFVPYPEHPGNETPTY
                     ISEHILGVMNYVEYVYGDGETRGSRKVDPSGKDIVRSCFLCHDPNALFRI"
     gene            1743..3539
                     /locus_tag="ACZPB4_13765"
     CDS             1743..3539
                     /locus_tag="ACZPB4_13765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3987 domain-containing protein"
                     /protein_id="HIR1099316.1"
                     /translation="MSDSLSRLVEAVRSAGVDIAPGYCEYVRLAFAIANDCGEAGREG
                     FIALCSLSVKFNREKAERLFSNALKKGDHRIHLGTAFHLAELAGVRLEPPSRPRDTHA
                     NNASNAAPFSHTRARDNNVEIEIEEQVDPFTHLPFFPEGHEWPRMLRQIMAFGQSREQ
                     RDVLLLGGLTTLGASLAQTLRFLYGGKWFFSSLQTFIVAPPASGKGVLAWTQMLVQPI
                     HDEIRATVAEEMKRYKKEMTSFNSLGREKAKAEEPEMPLNRMFIFSGNNTGTGILQNI
                     IDSGGVGIICETEADMVSNSIASDYGHWSEVIRSSFDHDPLSYNRRTDREYRELRHSH
                     LSVLISGTPGQVKPLIPSSENGLFSRQMFYYMPRVLHWINQFSLQRTDTSLEFQKLGK
                     DWIAHLREIQKLGVISLRLTDAQIVSFNEVFQTLFERSRKGTGNEMNSSVVRMAINIG
                     RILSIVALLRITGECEEAGDFAASLRKSPRLTPDPQTCSDNIKDGIITRWDLSIQEDD
                     FQAVLSLAEPMYLHAVHILSFLPANEVKNRGMADQERLFITLDTGFTYQSLLEEAEKL
                     KIPKNTACSCLQRWQKQGIVRKGEKRGDYKKT"
     gene            complement(3764..4003)
                     /locus_tag="ACZPB4_13770"
     CDS             complement(3764..4003)
                     /locus_tag="ACZPB4_13770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4248 domain-containing protein"
                     /protein_id="HIR1099317.1"
                     /translation="MQTNNEYLDEWPVRPYSKRELAMAYAPDISPCSALNRLAGWVRH
                     HQKLSHELDETGYQNRQRIFTSLQVELIFRYLGRP"
     gene            4231..4728
                     /locus_tag="ACZPB4_13775"
     CDS             4231..4728
                     /locus_tag="ACZPB4_13775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HIR1099318.1"
                     /translation="MALNYSVALRPNPLKKDEPAKAYATAQVNGELSLKQLSRRVSMQ
                     TTVSRADVVAVLISTVENLLDALQEGKQVDFGDLGKFRLQILNEGAESLEKFTSTNIT
                     GVNIQYIPGEDLKNIFAGLEFQPVASRKAQQAVLRAEKAGETSVDISKKPASGGDDSE
                     SPDEI"
     gene            5010..5108
                     /locus_tag="ACZPB4_13780"
     CDS             5010..5108
                     /locus_tag="ACZPB4_13780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="smalltalk protein"
                     /protein_id="HIR1099319.1"
                     /translation="MKKSVWSTILKVIIAVATAIAGAFGLQACQLF"
     gene            5425..5871
                     /locus_tag="ACZPB4_13785"
     CDS             5425..5871
                     /locus_tag="ACZPB4_13785"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011965948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_process: GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HIR1099320.1"
                     /translation="MKQYCFYQNYREVRLLVIHCSATRYDRDFPVEALRGAHKDRGFA
                     DIGYHYYITRDGELHRCRPENQIGAHASGWNDHSLGICYEGGLDERGLPADTRTYAQR
                     CTLLDLLRQLRRDYPSARILGHYQLSTNIRKACPCFDAEKEYAELY"
     gene            5950..6801
                     /gene="prmA"
                     /locus_tag="ACZPB4_13790"
     CDS             5950..6801
                     /gene="prmA"
                     /locus_tag="ACZPB4_13790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008276 - protein methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006479 - protein methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HIR1099321.1"
                     /translation="MNYYELSFTYTSPIEKEIINDVLAAELGKIGFESFTESEKGLLG
                     YISEALYDKKTLDDKLADFPLENTRIDYISKWVESKDWNEEWEKNYFKPIRIGNECII
                     RASFHEAEPGYTYNIIIDPKMAFGTGNHETTYLMISEMLKLDLEGKELLDMGCGTAVL
                     AILARLKGAKRVAAIDIDEWAYNNALENIRLNHTEDIQVALGGAEKIKEFGLFDIVFA
                     NINRNILLNDICQYTNSMKPGSILFMSGFYVEDIPAIEAECQKNGLKLDSYNERNNWV
                     AVKVLKG"
     gene            6891..7112
                     /locus_tag="ACZPB4_13795"
     CDS             6891..7112
                     /locus_tag="ACZPB4_13795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005641080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HIR1099322.1"
                     /translation="MKSVDSKLLLGLVVGAAVGAAVGYLAATDKREQLLEELNGVVGK
                     VKEGFNSALAKYKEGKQEVVQATEEIVAE"
     gene            7120..7527
                     /locus_tag="ACZPB4_13800"
     CDS             7120..7527
                     /locus_tag="ACZPB4_13800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HIR1099323.1"
                     /translation="MEKDSGTVFRELKEDVSAYVELKLELLKLSTYERTGKVIAVLSY
                     GLILLFLAFFAILFIFLALGFFLGDWLGSSGFGFGIVAVLYLLLIGIIIMNRDRISTK
                     VLNEVIAAMTANDDKNNATNDEQPANPTGETDF"
     gene            7487..7861
                     /locus_tag="ACZPB4_13805"
     CDS             7487..7861
                     /locus_tag="ACZPB4_13805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099324.1"
                     /translation="MNNQQTPLEKLISDKERIQRQCKRQEQKLNEDFSYIQENAGSLL
                     LSGLSSLLFPSNKSTTKTNDKNTAPVTAGQPSIALGISDYLSIAKGMIPIAWDLAQPF
                     IMTWGIKKAKKWFSNLLFKKKK"
     gene            8047..9048
                     /gene="gap"
                     /locus_tag="ACZPB4_13810"
     CDS             8047..9048
                     /gene="gap"
                     /locus_tag="ACZPB4_13810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008658781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HIR1099325.1"
                     /translation="MIKLGINGFGRIGRMVFRAAVANFGNDIQVVGINDLLDADYLAY
                     MLKYDSVHGRFDGEVAVEDGALVVNGNKIRLTAEMDPANLKWNEVDADVVVESTGFFL
                     TDETARKHIQAGAKKVIMSAPSKDATPMFVYGVNHTTYAGQDIISNASCTTNCLAPIA
                     KVLNDKFGIVKGLMTTVHAATATQKTVDGPSKKDWRGGRGILENIIPSSTGAAKAVGK
                     VLPVLNGKLTGMAFRVPTSDVSVVDLTVVLEKEASMADICAAMKEASEGELKGVLGYT
                     EDAVVSTDFRGCANTSIFDAKAGISLDSNFAKIVSWYDNEWGYSNKVCEMARVIAGK"
     gene            9118..10041
                     /gene="miaA"
                     /locus_tag="ACZPB4_13815"
     CDS             9118..10041
                     /gene="miaA"
                     /locus_tag="ACZPB4_13815"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HIR1099326.1"
                     /translation="MKSYELITILGPTASGKTTFAAALAAQLDTEIISADSRQIYRSM
                     DIGTGKDLADYNVNGKQIPYHLIDICEPGYKYNVFEYQHDFFRVYEDMKRRGKLPILC
                     GGTGMYIEAVLKGYKLLDVPQNPELRESLRNKTLEELETILASYKILHNKTDVDTAQR
                     AIRAIEIEEYYKTQAPDVNEYNPINSLIIGIHIDRELRREKISRRLRTRLDEGMVDEV
                     RTILATGVKPEDLIYYGLEYKFLTLYIIGELSFEEMVSQLEIAIHQFAKRQMTWFRGM
                     ERRGCEIHWIDATLPTEEKIATTMRILNNQL"
     gene            10038..10841
                     /gene="kdsA"
                     /locus_tag="ACZPB4_13820"
     CDS             10038..10841
                     /gene="kdsA"
                     /locus_tag="ACZPB4_13820"
                     /EC_number="2.5.1.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008676 - 3-deoxy-8-phosphooctulonate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0019294 - keto-3-deoxy-D-manno-octulosonic
                     acid biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-8-phosphooctulonate synthase"
                     /protein_id="HIR1099327.1"
                     /translation="MITINDLNKSENFFLMAGPCVIEGEDMALRIAEKIVGITERLHI
                     PYVFKGSYRKANRSRLDSFTGIGDEKALKILRKVSETFDIPTVTDIHETTEAAMAAEY
                     VDVLQIPAFLCRQTDLLVAAAETGKIVNIKKGQFLSPGAMQFAVQKVVDAGNDNVMIT
                     ERGTTFGYTDLVVDFRGIPQMQTFGFPVIMDVTHSLQQPNQTSGVTGGLPALIETIAK
                     AAIAIGTDGLFIETHPEPSQAKSDGANMLRLDLLEDLLTRLVRLRQAIL"
     gene            complement(10904..11554)
                     /locus_tag="ACZPB4_13825"
     CDS             complement(10904..11554)
                     /locus_tag="ACZPB4_13825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019539718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HIR1099328.1"
                     /translation="MWRVLTDKEREILRSNSTIQHFKRNELIYCEGDEPKDMMCLLKG
                     KVKIYKDGVGGRSQIIRMIKPVQYFGYRASFAQEDYLTNASAFEASTVCMIPMTVVTG
                     LLMSNPNLAMFFIRQLSIDLGISDERTVNLTQKHIRGRLAESLLFLKDSYGLEEDGAT
                     LSIYLAREDLANLSNMTTSNAIRTLSTFVAERIIALDGRKIKLIDEDRLKKISKMG"
     gene            11768..>13695
                     /locus_tag="ACZPB4_13830"
     CDS             11768..>13695
                     /locus_tag="ACZPB4_13830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5686 family protein"
                     /protein_id="HIR1099329.1"
                     /translation="MKKLYSILTLILISISIFAKSTDTYSDKILSFGKGNRETRERAD
                     SIMHLVIEKATQYQNTVSKYEAEIYIKGRTEILKQNMLIRLAHHIFPIDRKNKDMLFE
                     MVSQSKFNAPQNYLHDLKAVNGNSIPNGKKQQEALAFLNLNVYSPTAYDDAIFMPIAS
                     NAFKFYTFNLEGLETINGLTIYKIRFLPKQWSQKLVCGDLYVIDQSWTIDKIDMNGRY
                     SFAEFNLVMSYGRDFRRFILPEKADLFLRYRVLGNAVATTYHSSFKYQEVEWVEEDNE
                     SHKWKSLDLTNYYKLSSDTVPIIRDSTYWNIHRDNPLSPDEAHLYSKAQEQNISKIDT
                     ADDLQKYVKLTEQLTNTVNMDYKTTRIKYSGFLNPFQLGYSARNGITYKQRFRISKTF
                     ARDKQIRFRPEIGYVFKRKQIFFKVGGDWEYSPQKRGILSVEVGNSNESYSSEITQKI
                     NEELKDSTFNFDDLNLEYFKHYYAEIKNSIELFNGFQLTTGISYHRRIPSKKKVAIDP
                     GDDVEEILSQNYNDFTPTLGFSYTPRQYYRMDGYRKEYVYSYYPTISIEIARGIPGVG
                     KSSGDYGRIEADVHQSLMLGLCRRLNYHISAGLYTQQKSTYFADFRYFTRRNFPDTWD
                     DQIGGVFNLLKGEWFNAS"
BASE COUNT         3807 a         3364 c         3214 g         3310 t
ORIGIN      
        1 aatctcttac cccacctcgg ataccggttt atacacgctc tcgaagcaag cccggttcac
       61 cgccgacaga cgttccaagg aaaagctctt caagtaaatt tgcgtggtct tgatagacgt
      121 atgccccaac agctcgctga tcatctcgat cggtacgtcc tgttccttca aggtcgtggc
      181 gaaagagtga cggatcgtgt acgaggtgac cggctcaccc acaccacaag tctccgccag
      241 cgacctcaag tcgcggttaa agcgcaacaa ggcgccgttg tattccgcat aggccgcctc
      301 acccgttttc ttcccgctca gaaacgggaa caggtaaggc gagtccttgt ccgtgcaaac
      361 cgccaactca tccaacaaga gccgtacatc ggccgggatc tccacccgga tgaaagaccc
      421 gctcttctga cggtggtacg acaagacccc gtccttgaca ttctctttcc gcaaatgggc
      481 gaaatccacg aacgccatcc cgctgaacga gaacatcagg caaaaacaca gctgggttct
      541 ccgcatctcc ggctcaactc tcggagtccc catcaacgag cgcaagctat ccagaggcaa
      601 cgccttcttc cgcttgctct ccacgcctgt aaacaccccc ttgaacagat tcgggatata
      661 cgaaacctca ccagcctcca ccgccaagtt atagatatgc cggattcgcc gcatataggt
      721 ggacaccgta ttgcgcatac agccccgctt cgacagccat gcctgataaa gcaagagcct
      781 ctctttgtct atataggcat aagggatttc ctccatcccg caaaaacact tgaacgagcg
      841 taaagcgtcc agataactct tcgccgtgga ataacgcccc acctcacgaa ggtgggctat
      901 ataagccaac atacccgcca ccacgtcttc ttttttcata taaatcctcc ttaaatcctt
      961 gtttattctg ttatctttta tttaatcatg tcaacaccat taacattggg acgaactgtt
     1021 cgtcccgcac tttattttat taatccgacc ttcaccgccg ttaatctaag aaaaaagaat
     1081 acatgaaaaa tgaatttaaa atgtcccttt tcgcagcccc gatctcaccg gtcaaagata
     1141 gcctaacggg acgagtatca cgaccggcta ccgtatatcc cagtcgagaa gtcaccttac
     1201 aggaggtggt ccgactcatc accggcgatc cggccctcga acgcctcacc cggcagctcc
     1261 gcctcccgct tgagacgggt gacaaggaac gattcagcga gctgaaacgg caaacgctac
     1321 cgtatgtcac gccttgcggg actttctcct accggaaaag cgatcggctc ctggccccga
     1381 gcggattggt ggtagtggat gtagacggat tggactctac cgcggaggcg gaagccctcc
     1441 gaagacagct gttcgacgat gcctacctat gccccgctct ctgcttcatc agcccgagcg
     1501 aacgaggcgt aaaggctttc gtcccctatc cggaacatcc cggaaacgag acacccacct
     1561 atatctccga gcatatccta ggcgtgatga actacgtgga atatgtgtat ggcgacggag
     1621 agacgcgagg ctcccggaaa gtagacccga gcggcaaaga catcgtccgc tcctgtttcc
     1681 tatgtcatga tcccaatgcg ctcttcagga tttgaaatca taactcataa atgataaatt
     1741 acatgtcaga cagtttatcc cgcttagtag aagcggttcg ttcggcgggt gtagatatcg
     1801 cccccggata ttgtgaatac gtgcgcttgg cgtttgccat cgccaacgat tgcggcgagg
     1861 caggacgaga agggttcatc gccctgtgtt ccctatcggt gaagtttaac cgggagaagg
     1921 ccgaacggct tttctccaac gccttgaaaa agggagacca caggatacac ctcggtacgg
     1981 ccttccactt ggccgaactg gcgggcgtac gcctggagcc tccaagccgc ccccgcgata
     2041 cgcacgcaaa taatgcaagt aatgcagcac ctttttccca cacacgtgcg cgcgataata
     2101 acgtagagat cgagatcgag gagcaggtcg atccgttcac ccacctgccc ttcttccccg
     2161 aggggcatga gtggccccgg atgttgcggc agatcatggc gttcggacag agccgggagc
     2221 aacgggacgt actcctcctc ggcgggctca ccaccttggg cgcctcgctc gcccagacgc
     2281 tacggttcct atatggaggc aaatggttct tctccagttt gcaaaccttc atcgtcgctc
     2341 cccccgcctc cggaaaaggc gtgctcgcat ggacgcaaat gctcgtgcaa ccgatccacg
     2401 acgagatccg ggcgaccgtg gcggaggaga tgaaaaggta taagaaagag atgacctcct
     2461 tcaattcctt gggacgggaa aaggcgaaag ccgaggaacc ggaaatgcct ctcaaccgta
     2521 tgtttatatt ctccggcaac aacaccggta ccggtatctt gcagaatatc atcgactcgg
     2581 gcggcgtggg gatcatctgc gagaccgagg cggacatggt cagcaactcc atcgcctcgg
     2641 attatggcca ttggagcgag gtgatccgca gctcgttcga tcacgaccca ctcagttaca
     2701 accggcggac agaccgggag tatcgggagc tgcggcactc ccacctgtcg gtattgataa
     2761 gcgggacgcc cgggcaggtg aagccgctga tcccttccag cgagaacgga ttgttctccc
     2821 ggcaaatgtt ctattatatg ccccgtgtac ttcactggat caaccagttc agcctacagc
     2881 ggaccgacac gtcgctggaa ttccagaaat tgggcaagga ctggatcgct cacttgagag
     2941 agatccagaa actgggggtg atctcgcttc gcttgaccga cgcgcaaatc gtctccttca
     3001 acgaggtgtt ccaaaccttg ttcgagcgct cccggaaggg caccggcaac gagatgaaca
     3061 gctccgtcgt acggatggcc atcaatatcg gacgtatcct gtcgatcgtc gccctattgc
     3121 gaataacagg ggaatgcgag gaggcgggag acttcgccgc cagcctgcgc aagtcgcccc
     3181 ggctcacgcc agacccgcag acctgctccg acaacatcaa ggacgggatc atcacccgct
     3241 gggatctctc catccaagag gatgatttcc aagcggtcct ttccttggcc gagcctatgt
     3301 acctacacgc cgtacacata ctctcgttcc ttcccgccaa cgaggtgaag aaccggggca
     3361 tggccgacca agaacgtctc ttcatcacct tagatacggg tttcacctat caatccctct
     3421 tggaagaagc cgagaagctg aagataccca aaaacaccgc atgcagttgc ttgcaacgtt
     3481 ggcagaaaca gggaatcgtc cgaaagggag aaaaacgagg ggattataag aaaacataat
     3541 ccctcttcct cctcttcttt taagtatgta cgcacgtgtg tgggaaaaca ggtactgcat
     3601 tacttgcatt atttgcatta ctcgcacgcc ccacacgtac accggcatcg cctcacgcct
     3661 acgcccgtat agggccacgg cgatatacgt gtgggctaac gtcaatatac gcatgaagcg
     3721 atgccgatat acgcatgcga aagcgaacgt ggaagaccct cgttcaagga cggcccaaat
     3781 agcgaaagat cagttccact tgcagggagg tgaaaatccg ctgccggttt tggtaacccg
     3841 tctcatccag ctcatggctg agcttctgat gatgtcggac ccatcccgcc aagcggttga
     3901 gggcggaaca cggactgata tcgggagcat aggccatggc caactcccgt ttgctataag
     3961 ggcgcaccgg ccactcatcc agatattcgt tgtttgtttg cataaaatag gtgtttttca
     4021 attcatttac aggaataaag atactgaaaa agtacgaatc cggcaacgat ccgatccact
     4081 aatattcatc ttttatcacc ttattcccct cgatttcaca ccgcctctac gagactcatt
     4141 ccggaggaaa ccggaagtcg tacattcgta atcgaaaaca gatcgatccc attttcaatt
     4201 atcaattatc aatttttaat tatcaaaact atggcattaa attacagtgt ggcccttcgg
     4261 cccaacccct tgaagaaaga cgagccggcg aaagcgtacg ccacggcaca ggtcaatgga
     4321 gagctgtcgc tcaagcaact gagtcgccgg gtatccatgc aaaccaccgt cagccgtgcg
     4381 gacgtggtag cggtattgat ctccaccgtc gagaacctgc tcgatgccct ccaagaggga
     4441 aagcaggtgg atttcggcga tttaggcaaa ttccgtctac agatactcaa cgagggggcg
     4501 gagagtcttg agaaattcac atctacaaac atcaccggtg tcaacatcca gtatataccg
     4561 ggtgaggacc tgaagaacat cttcgccgga ctggagttcc agccggtggc cagtcgcaag
     4621 gctcagcaag ccgtgcttcg tgcggagaag gccggggaga cctctgtcga tatcagcaag
     4681 aagcccgctt ccggagggga cgactcggaa tcgcctgacg agatctagcg tgtcactttt
     4741 ggcttacacc caatcggtat gtcacttttg gcttgaccca aaagtaacca aaaggtcaag
     4801 gctgacgctg acgggctact tcgagacctg cgctcgctgt cgcatcccaa ctcgctgcgc
     4861 tcaaacaggg acgctcctgt cgctcacttc ggccgcctcg ctttacgccc gtccgctgag
     4921 gccgtccaaa ggaaagcgtc gctttcctct tatatcagcc gggataccat tattcattat
     4981 tcattgttca ctattaatta ttaattatca tgaagaagtc tgtttggagt accattctca
     5041 aagtgatcat cgccgtagcc accgccatcg cgggggcctt cggcctgcaa gcttgccaat
     5101 tgttttagca agcctccccc acccgttccc actccctaaa gaagacaacc tccccaaaag
     5161 aggacaccct ctaccagaag gacagtcttt ctcaaggggc cggcctctcc tcaaagagcc
     5221 gggacggctc tccctccggc cttagcgggc gggcgtaaag tgaggcggcc gaagtgagcg
     5281 acaggagtgt ccctgtctga gcgaagcgag ttgggacgcg acagcgagcg aaggccgacg
     5341 agtagcccgt ccgcgtcagc cttgaacttt tggttacttt tctttcaaga gaaaagtaac
     5401 acacaaacaa aaaaaagaat aaaaatgaaa caatattgct tttaccagaa ttacagggag
     5461 gttcgcctcc ttgtaattca ttgcagcgca acacgctacg accgggattt tcccgtggaa
     5521 gcgcttcgag gcgcacataa ggatcgtggg ttcgctgaca tcggctatca ttactatatc
     5581 acccgggatg gcgagctgca ccgctgccgg ccggagaacc agatcggggc acacgcctcg
     5641 ggctggaacg atcacagtct gggtatttgc tacgagggcg gattggatga gcgaggtctt
     5701 cccgctgata cccgcaccta tgcccagcgt tgtaccctgc tcgatctctt gcggcagcta
     5761 cgccgtgatt acccgtcggc acgtatctta ggacattatc aactcagcac caacattcgc
     5821 aaggcttgcc cctgcttcga cgcagagaaa gaatatgcgg aattgtatta ggcttcgtga
     5881 tatttgaata ggcaacagat tttttcgtat gtttgcggac aatatagaaa ataaacaaaa
     5941 agatacgaca tgaactatta cgaacttagt ttcacataca cctctcctat cgagaaagag
     6001 attatcaatg acgtgctggc cgccgagttg gggaaaatcg gttttgagag ctttacggaa
     6061 agcgagaagg gtttgctggg atatatatcc gaggctttat acgacaaaaa gacattggat
     6121 gataaactgg ccgactttcc gctagagaat acccggatcg attacatctc caaatgggta
     6181 gaaagcaagg attggaatga ggagtgggag aaaaattatt tcaaaccgat ccggatcgga
     6241 aacgagtgca ttatccgtgc ctccttccac gaggcggagc ccggctatac atataatata
     6301 ataatagacc cgaaaatggc tttcggcacc ggcaatcacg aaacgactta tttgatgata
     6361 agcgagatgc tgaaactaga cctagaaggc aaggagctac tggatatggg atgcggcaca
     6421 gccgtgctgg ccatcttggc ccggctgaaa ggggcgaaac gggtagcggc catcgacatc
     6481 gacgaatggg cttataacaa cgccctagag aatatccgcc tgaatcatac cgaagacata
     6541 caagttgcct tgggcggcgc cgagaaaatc aaggaattcg gactattcga catcgtcttc
     6601 gccaatatca accggaacat cctcctgaat gacatttgtc aatatacaaa cagtatgaaa
     6661 ccgggaagca tcctatttat gagcggcttt tatgtagaag atatcccggc gatagaagca
     6721 gaatgtcaga agaacgggct gaaattggat tcttataacg aaagaaataa ctgggttgcc
     6781 gtgaaggtct taaaaggata acttttttta acagcaaaag ttaagacaag gataaacctt
     6841 aatccaaata aatacgttat cttagtggaa acttctaaaa agaaaaagtt atgaaaagcg
     6901 tagattcaaa attattactt ggccttgtag taggcgcagc tgttggtgca gctgtaggtt
     6961 atttggcagc gacagataag agagaacaat tactggaaga attgaacggt gttgtcggaa
     7021 aagtaaaaga aggttttaac tccgctcttg ccaaatataa agaaggaaag caagaagtag
     7081 tacaggcaac agaagaaatc gtagctgaat aagctttgta tggagaaaga ttcaggaaca
     7141 gtcttccgtg agctgaaaga agatgtatcg gcttatgtgg agttaaaact tgagctccta
     7201 aagttgagta catatgagag aacgggtaaa gtcatagccg ttctctcata tggcttgata
     7261 ttattgtttt tggcattctt cgccatcttg ttcatattct tggccttggg cttcttccta
     7321 ggggattggc tcggctcctc cgggttcgga ttcggtatcg tggcggtctt gtacctgcta
     7381 cttatcggca ttataataat gaatagggac aggatcagca caaaagtatt aaatgaggta
     7441 atagccgcca tgacggcgaa tgacgataaa aataacgcga caaacgatga acaaccagca
     7501 aaccccactg gagaaactga tttctgacaa agaacgcata cagagacaat gtaagcggca
     7561 ggaacagaaa ttgaatgagg atttctctta tatacaggag aacgccggaa gtttgttgtt
     7621 atccggacta tcgtctctcc ttttccctag caataagtca acgacaaaaa caaacgacaa
     7681 gaacacagct cccgtaacag ccggacaacc ctccatcgct ttagggatct cagactattt
     7741 atccatagcg aaaggcatga ttcccatcgc ttgggatctc gctcaaccat ttattatgac
     7801 gtggggaatc aaaaaagcga aaaaatggtt ctcaaatctc ttattcaaga aaaagaaata
     7861 acctccaaca attaatttat gttagagggc agtttttttc tcgctatatt ataaggctca
     7921 atacaaaaaa catgactaca tttgcagtcg ttaaagcaag gataaaatga atatctactc
     7981 cttgcgatgg ataagagata aaaataaaga cttattatta ataaacccat aaaaagtttt
     8041 attacaatga tcaaactagg tattaacggt tttggccgta tcggacgtat ggtgttccgt
     8101 gctgcagttg ctaactttgg caacgatatt caagttgtag gtatcaacga ccttttggat
     8161 gctgattact tggcatacat gttgaaatat gactcagtac acggtcgttt cgacggcgaa
     8221 gtagctgtag aagacggcgc tttggttgta aacggtaaca agatccgttt aactgctgag
     8281 atggatcctg ctaacttgaa atggaacgag gttgacgctg acgttgttgt tgagtctact
     8341 ggtttcttct tgacagatga gacagctcgc aagcacatcc aagctggcgc taagaaagtt
     8401 atcatgtctg ctccttctaa ggacgctact cctatgttcg tttacggtgt taaccataca
     8461 acttacgcag gtcaagacat tatctctaac gcttcttgta ctacaaactg cttggctcct
     8521 atcgctaagg ttttgaacga caagttcggt atcgttaaag gtttgatgac aacagttcac
     8581 gctgctacag ctactcagaa gactgtagac ggtccttcta agaaagactg gagaggtggt
     8641 cgtggtatcc ttgagaacat catcccttct tcaacgggtg ccgctaaggc tgtaggtaaa
     8701 gtattacctg tattgaacgg caaattgaca ggtatggctt tccgtgtacc gacttctgat
     8761 gtttctgttg ttgacttgac agtagttctt gagaaagagg cttctatggc tgacatctgc
     8821 gctgcaatga aggaagcttc tgaaggcgaa ttgaaaggtg ttcttggtta tactgaagac
     8881 gcagttgttt caactgactt ccgtggctgt gctaacactt ctatcttcga cgctaaagct
     8941 ggtatctctt tggattctaa cttcgctaag atcgtatctt ggtacgacaa cgagtggggt
     9001 tattcaaaca aagtttgtga gatggctcgc gttatcgctg gtaagtaatt tattaccact
     9061 ctacatagaa aaggctatcc tctttgagga tggccttttt tttcgtacgt ttgtatcatg
     9121 aaatcatatg aacttatcac gattctaggg cctacggctt ccggaaagac gaccttcgcc
     9181 gccgctctcg ccgcccagtt ggatacggag atcatcagcg ctgattctcg gcagatctat
     9241 cgttctatgg atatcgggac gggtaaggat ttggccgatt acaacgtgaa tggaaaacaa
     9301 atcccctatc acttgatcga tatctgcgag cccggctata aatataacgt atttgagtat
     9361 cagcatgact ttttccgggt ctatgaggat atgaagcgga ggggtaaact cccgatctta
     9421 tgtggaggaa ccgggatgta catagaggcc gtactaaaag gatataagct attagacgtg
     9481 cctcaaaatc ctgagctaag ggaatccttg aggaataaaa ccttggagga actggaaacc
     9541 atcctcgcct cttataagat attacataat aaaacggacg tggacaccgc ccagcgggct
     9601 atccgtgcga tcgagatcga ggagtattat aagactcagg caccagacgt aaatgaatat
     9661 aatccgatca acagcctgat catcggtatc cacatcgacc gggaattacg tagggaaaaa
     9721 atatccagac gcttgcggac ccggttggac gaaggaatgg tggatgaggt tcgtacgatc
     9781 ttggctacgg gtgttaaacc ggaagacttg atctattacg gattggaata taagtttctt
     9841 actttatata ttatcgggga gctttctttt gaggagatgg tctcgcaact cgagatagcg
     9901 atccatcaat tcgccaagag gcaaatgact tggttccggg gcatggagcg ccggggttgc
     9961 gagattcatt ggatagacgc cactctaccg accgaagaaa aaatagcgac aacaatgcga
    10021 attctaaata atcagctatg ataacaataa acgatctaaa taaaagcgag aacttcttct
    10081 tgatggcagg tccttgcgta atcgaggggg aagatatggc gttacgtatc gccgagaaaa
    10141 tagtgggtat cacggaaaga ctgcatatac cctatgtatt caaaggctcc tatcggaaag
    10201 cgaatcgctc ccgtctggat tctttcacgg gcatcgggga tgagaaggcg ttaaagatct
    10261 tacggaaggt gagcgagacg ttcgatattc ccaccgttac cgacatccat gagacaacgg
    10321 aagctgccat ggccgccgaa tatgtcgatg tccttcaaat cccggctttc ctatgccgcc
    10381 aaacggattt attggtagcg gcggccgaga ccgggaagat cgtcaatata aagaaaggac
    10441 agttcctttc gccgggtgcc atgcaattcg ccgtacaaaa ggtagtggac gcaggaaatg
    10501 ataatgtcat gatcaccgag cggggaacga cattcggcta taccgacctt gttgtcgatt
    10561 tccggggtat cccgcaaatg caaacattcg gtttcccagt cattatggat gtaacccatt
    10621 ccttgcaaca gccgaaccaa acctccggcg tgaccggtgg attgcccgcc cttatcgaga
    10681 cgatagcgaa agccgctata gccataggca cggacggcct gtttatagag acccacccgg
    10741 agccaagcca agccaaatcc gacggggcca atatgctcag actggattta ttagaagatc
    10801 ttttgacacg tttggtacgt ttacgccaag cgatcctata aaaaataagg ggcccttact
    10861 aaaaaggccc ctttatttct tatttttacg atcaataatc taattatccc atcttgctga
    10921 ttttcttcaa ccgatcttca tctatcaact taatctttct accgtctaaa gcaatgatac
    10981 gttccgccac aaaggtagac aacgtgcgaa tagcattcga tgtagtcata ttagatagat
    11041 ttgccagatc ttcacgagcc aaatagatgc ttaacgtagc accgtcttct tccagtccgt
    11101 aactatcttt caggaataac aaagattcag ctaatcgccc acgaatatgt ttttgcgtaa
    11161 ggttaaccgt acgttcatcc gagataccga gatcaatgga taattgtcgg atgaaaaaca
    11221 tagccaaatt cggattactc attaaaaggc ccgtaaccac tgtcatagga atcatgcaaa
    11281 ccgtagaagc ctcgaatgcg gaagcgttcg tcaagtaatc ttcttgagcg aaactagccc
    11341 ggtaaccaaa atactgcaca ggcttaatca ttcggataat ctggcttctg ccacctactc
    11401 catccttgta aatcttcact ttacccttta acaagcacat catgtccttt ggttcgtcgc
    11461 cctcgcaata aatcaactcg ttacgtttga aatgctggat cgtcgaatta ctacggagga
    11521 tctcacgttc cttatcggtc agaaccctcc acacctctga taaactggcc gataaatcga
    11581 cctcttcttt ttgctgttta accacgactg ctatataaca tacttatgaa gcacaaatat
    11641 acgatttttc ttttgataaa ataaaaactt ttgtacgatt aattacacca tattgtaaca
    11701 ttttactttc tttcacgtct aaactgaaat ttattcatta tgtttgtctg gaaagaatgt
    11761 aaaatcgttg aaaaagttat attcgatact taccttgatt ttaatctcta taagtatttt
    11821 cgcaaagagc actgatactt atagtgataa gatcctgtct tttggcaagg ggaatcgaga
    11881 aacgagagaa cgggcggact cgatcatgca ccttgttatc gaaaaggcaa cccaatacca
    11941 aaatacggta tcgaaatatg aggctgagat ctatatcaaa ggacgtacag aaattttaaa
    12001 acaaaatatg ttaatacgtc tcgcccacca tatcttccct atcgaccgaa aaaataagga
    12061 tatgcttttt gagatggtca gccaatctaa atttaacgct ccgcagaact atcttcacga
    12121 tctaaaggcg gtcaacggaa acagcatacc caacgggaaa aagcaacagg aggccttggc
    12181 cttcttgaat ttgaacgtat actcccctac cgcttacgat gatgctatct tcatgccgat
    12241 agctagcaac gcttttaagt tttatacatt caatctggaa gggttggaga ctatcaacgg
    12301 cttgacgatt tacaaaatcc gtttcctgcc gaagcaatgg agccagaaat tggtatgcgg
    12361 ggatctatat gtcatcgacc agtcatggac gatcgataag atcgatatga acggtcgtta
    12421 ctctttcgcc gaattcaacc tagtcatgag ctacggacgg gatttcaggc ggttcatcct
    12481 gcccgagaag gcagatctat tcctccgata cagggtattg ggaaacgcgg tagcaaccac
    12541 ctaccattct tcctttaagt atcaggaagt ggaatgggtg gaggaggaca acgaaagcca
    12601 taagtggaaa tccttggacc tgaccaatta ttacaaactc tcgtccgata cggttcctat
    12661 tatcagggat tccacgtatt ggaatatcca tcgtgacaat cccttgagtc cggatgaagc
    12721 ccacttatac agtaaagccc aagagcagaa tataagtaaa atcgatacgg ccgatgatct
    12781 ccagaagtac gttaagctaa cggagcagtt gacgaatacg gtcaatatgg attataaaac
    12841 gacccgtatt aaatattccg gctttctaaa tccgttccaa ttgggttatt ccgcccgtaa
    12901 cggcatcact tacaaacagc gattccgtat cagcaagaca ttcgcccgtg acaaacaaat
    12961 tcgtttccgt ccggagattg gttacgtatt caagcgcaag cagatatttt tcaaggtcgg
    13021 aggcgattgg gaatactcgc cgcagaaacg gggaatttta tcggtagaag taggaaacag
    13081 taatgagagt tattcttccg agatcaccca aaagatcaat gaggaattga aggattccac
    13141 cttcaatttc gatgatttaa accttgagta tttcaagcat tactatgcgg aaataaaaaa
    13201 ctccattgag ttattcaatg ggtttcaatt aacaacaggc atctcttacc atcgccgtat
    13261 cccctctaaa aagaaagtgg cgattgatcc cggggatgat gtagaggaaa tacttagcca
    13321 aaattataat gactttacgc ccacgctcgg tttctcctat accccccgcc aatattatcg
    13381 catggacgga taccggaagg agtatgtcta ttcttactat cccacgatat caatcgaaat
    13441 agcgagaggt atccccggag tcgggaaaag ctcaggagat tacggacgta tagaggcaga
    13501 cgtgcatcaa agccttatgc ttggcctgtg cagacgattg aactatcata tcagcgccgg
    13561 tctttataca caacagaagt ctacctattt cgcagacttt aggtatttca cccgcaggaa
    13621 tttccccgat acatgggatg atcagatcgg cggagtcttc aatctgctga aaggcgagtg
    13681 gttcaatgcc tccga
//
LOCUS       DBMDTB010000101        13694 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_1382_length_13694_cov_11.170088, whole genome shotgun
            sequence.
ACCESSION   DBMDTB010000101 DBMDTB010000000
VERSION     DBMDTB010000101.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 13694)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 13694)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13694
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1382_length_13694_cov_11.170088"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..3434)
                     /locus_tag="ACZPB4_13835"
     CDS             complement(<1..3434)
                     /locus_tag="ACZPB4_13835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase 2 galactose-binding
                     domain-containing protein"
                     /protein_id="HIR1099330.1"
                     /translation="MRTFSKKKKLPRLLTLCGAVAVSALLGGCGQSGVPAESFDRSDY
                     YTRGIGSYPGDPGEDFSPSLRPDYSTYRNIALLRSAYNSSSYDYNLTAQLVTDGVISD
                     KQPQYLDLSTQNGDIARREREWMIDQGPYSRNAVTGEDAYFLFTLNNWKEKADKVQFR
                     GSVAYDENKIKDGYEIVCEGSNDGNTWTELAALKDKGMPGKASKYKAHSDPNKNSWDP
                     GTLPTRMLNETLTFDQPGEYAYYRMRLKMEGAAYWAFFEMNFYNQDKLIDLLPSKFFN
                     SAWMSATTGEEWVYVDLGSQSEFDKVKLHWINKAIKGKIQVSDDAKQWVDIANLPGGD
                     ANLDEIKLKGKGRYVRVWMEQPANDGRYILSEIEVMGKGGLLAQPAAAPAATKDEIRL
                     SGGNWKVQRASEVTASGEEISKPSFSPENWIVATVPGTVLSSYKNIGAIPNPNYADNL
                     MQISESFFNSNFWYRDEFEVPEGFKQDRLFLNFDGINWKANVYLNGNKIGRIEGAFIR
                     GVFDVTDRVVPGKNVVAVEIIKNEHIGAIKEKCEKNTDFNGGILGADNPTFHASIGWD
                     WISTIRGRNIGIWDDVYLTSTGKVTIQDPFVQVVLPLPDTTSATLTPEVIVKNHDAAP
                     VKGVLTGKIGDITFEQPVELAANEEKTVTFDPNSFSQLKVQNPRLWWPKGYGSPYLYD
                     ANFTFKVGDKVSDSEDFKVGIRQMTFNENNSILSLFINGRRFIGRGGNWGFGESNLNY
                     RGREYDIAVAYHADMNFTMMRNWVGQIGDKELYEACDRHGIMIWQDFWLANPSDGPDP
                     YDPEMFIANAEDYVKRFRNHASIGIYCGRNEGFPPEQIDKALRRIVKEDHPGLHYISS
                     SADEVVSGHGPYRALPVKEYFSLKNGSDKFHSERGMPNVMNYESLVRTFSPEALWPQN
                     AQWGQHDYTMEGAQSCASFNAIIEKGFGKPNNAKEFADLAQWVNYDGYRGMFESRSLN
                     RKGLLLWMTHPAWPSMVWQTYDYYFEPTAAYFGCKKASEPLHIQWNPVTDEIEVVNYS
                     AGVRNGLTAKAQIINMDGSISWENEVSVDSKEDTTNKCMKLDFPASVSSAHFVKLTLT
                     ENGKIVSDNFYLRGVEEGNYQALREMPKVTLRSNVATNKGNDGTWTATATLENTSST"
     gene            complement(3467..4246)
                     /locus_tag="ACZPB4_13840"
     CDS             complement(3467..4246)
                     /locus_tag="ACZPB4_13840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HIR1099331.1"
                     /translation="MSTILFDKIVFGPIHSRRLGVSLGMNLLPTDGKLCSFNCIYCEC
                     GLNENHRTHSKLPTRTEVREALEQKLSSMKAEGIAPDVITFAGNGEPTIHPEFGGIID
                     DTIATRDRFFPDAKIAVLSNSTMLQKEEVFQALNKIEDNILKLDSVLDSRIRQIDVPN
                     SPAFNFESLLKQLCRFNGNLIIQTMFLKGEVNGKSVNNMTEEEIAGWISALKQIRPKQ
                     VMIYTIDRETPVKALKKATKEELDAIAERARKEGFDVTVSY"
     gene            complement(4280..6340)
                     /locus_tag="ACZPB4_13845"
     CDS             complement(4280..6340)
                     /locus_tag="ACZPB4_13845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HIR1099332.1"
                     /translation="MKRLFIILSIILLINSYYANSQIEYSVDKWMEYVEELALETEDT
                     ERIESLYADLSYLIEHPFDLNAVTEEQLKRLPFLSDRQIEQLLSYRKRYGNMVSIYEL
                     KNIEDIDFQTISLLLPFVYIGDNLVEKRLLTVKNLLKYGHNELQIRYDQCFQQKKGYG
                     EQTDSILLLYPNRKYRGEPFYHSLRYSYTFEDRLQAGFVAEKDAGEPFWNAYHKGYDF
                     YSAHLFLKDINWLKSLAIGDYKMSFGQGLVISNDFSPSRTAVVAQAERRTNGFRRHFS
                     TNEQDFFRGVASTITIKNLDISVFYSYRKMDAAVDSLTFTSLKTDGLHRLQRDWEKRK
                     MITMQVYGGNIRYATSHFHVGLTALSYSFGKFNIDPDPKPYNLFYFRGSNNFNIGVDY
                     MLKSNRIKFYGETALSKNGAISTLNALQLTPASYISFLVLYRYYDRRYQALFGNAFSQ
                     GSTVQNEQGVYMGLQLTPIARWKLSVYADLFRFPWLKYGIDAPSGGQEYMAQIDYTPS
                     RNYSAYLRYKYRQKEKNGTFENDNLLKINTYKQHRIRFQQVYNFSSPFIFKTSLDGIL
                     FDDPIKKLNKGIMISQSIGWKPTTLPLQIDGYLAWFHTDDYNSRVSSYEKNILYAFNM
                     PSFYGDGMRFALTFRLDIWKRLSLSAKLAHTHYWDRDLIGTDTEEISGSDKTDLYALL
                     RWKF"
     gene            complement(6354..7163)
                     /locus_tag="ACZPB4_13850"
     CDS             complement(6354..7163)
                     /locus_tag="ACZPB4_13850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PorV/PorQ family protein"
                     /protein_id="HIR1099333.1"
                     /translation="MKYLLLSLFAGVFSLYVHGVDNLRLPDVRSVGMGGNVATQSILF
                     NPALIVDKDKKSIHLEYFNRYMLKELGTMSGSFYYPNQLLSAGVDISVFGFDKYREMM
                     VRVLGGKRLGDQWALGLGVHYSFLQTDLLENTRSRLSTDLGITFSPIDKLLIGMLIMN
                     LPSVSIGDKDIEIEDFNYYLIQISFQWEIINSLLITGSAGTENENLVVGNLGLEYTAF
                     DSFFIRAGIQTAPLLPSLGIGYNFSCFTIDVASIYHPILGMSTSLGLSFSF"
     gene            complement(7185..8012)
                     /gene="dinD"
                     /locus_tag="ACZPB4_13855"
     CDS             complement(7185..8012)
                     /gene="dinD"
                     /locus_tag="ACZPB4_13855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA damage-inducible protein D"
                     /protein_id="HIR1099334.1"
                     /translation="MKKEEITALFGKFESISCEVEGIECWSARELQPLLGYAKWDNFI
                     NNVVVKAKEACRNAGEDVQNHFPDVGKMVSIGYGVEKQIDDILLTRYACYLIAQNGDS
                     RKPQVAFAQTYFAVQTRKAEVIEQRLLDCERLKAREKLSQTEKQLSGILYERGIDNKG
                     FAIIRSKGDQALFNLSTQMLKKRMNVPTNRPIADFLPTISIKAKDLATEMTNVNVQAK
                     DLYGQSPIEKEHIDNNTAVRDMLLQRGIKPEQLSPNEDIKKVQRRINKDNKKNLKNK"
     gene            8132..8737
                     /locus_tag="ACZPB4_13860"
     CDS             8132..8737
                     /locus_tag="ACZPB4_13860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4294 domain-containing protein"
                     /protein_id="HIR1099335.1"
                     /translation="MIRKGIYCILALLALCSFKGMAQAVKTNIVPEGYQKAQLYEGDT
                     MAVVNLREVFIYPQVKFKNKREQAKYNKLVRDVKRTLPYAKMVYDTLIETYEYMETLP
                     NDKARQAHLKRMEKELFAQYKPELKKLSFSQGKLLIKLIDRECNQSSYNLLKAYLGSF
                     RAGFWNFFAGMFGASLKSEYDPKGKDAMTERVVVLVENGLI"
     gene            complement(8729..9259)
                     /locus_tag="ACZPB4_13865"
     CDS             complement(8729..9259)
                     /locus_tag="ACZPB4_13865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008156053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HIR1099336.1"
                     /translation="MRKLKVTELNRLTPEAFKESKKIPLIVVLDHVRSLNNVGSVFRT
                     SDAFRVEAIYLCGITACPPNAEIHKTALGAEETVDWEYFKDTPEAVDKLRQEGYTVCA
                     VEQAEGSVMLDNLQLDKTKKYAIVMGNEVKGVQQNVVDNCDICIEIPQYGTKHSLNVS
                     VTTGIVIWDFFKQLSD"
     gene            9956..10942
                     /gene="nadA"
                     /locus_tag="ACZPB4_13870"
     CDS             9956..10942
                     /gene="nadA"
                     /locus_tag="ACZPB4_13870"
                     /EC_number="2.5.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010801171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008987 - quinolinate synthetase A
                     activity [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD+ biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="quinolinate synthase NadA"
                     /protein_id="HIR1099337.1"
                     /translation="MLTNQSIGYMDAPVPKDLDLKEAIDKLRKEKNAIILAHYYQTGD
                     IQDIADYVGDSLALAQWAAKTKADIIVLCGVHFMGETAKILCPDKKVLVPDLNAGCSL
                     ADSCPATEFAEFVKQHPGHTVISYVNTTAAVKAVTDVVVTSTNARQIVESFPEGTPMI
                     FGPDRNLGNYINSITGRNMLLWDGACHVHEQFSLEKILSLKKQYPNAEVITHPECKQP
                     VIQVSDFVGSTAALLKHTIKSDAKQFIVATESGVIHEMRKQSPDKEFIPAPPNDSTCA
                     CNECNFMRLNTMEKLYNCLKFEMPEIFVDKEVQKKAIKPIKKMLEISEKLGL"
     gene            11524..>13694
                     /locus_tag="ACZPB4_13875"
     CDS             11524..>13694
                     /locus_tag="ACZPB4_13875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor domain-containing
                     protein"
                     /protein_id="HIR1099338.1"
                     /translation="MKKIGLMLALLWVICALSWASSPDARIKGQLIDASTNQVINYAD
                     IFLFTMGSEKPLQQTFPDDQGRFSFTKVAPGNYVVMVRLMGYDVFTKNDIILDASSPV
                     DLGKLMMSPLEVGIAEVEVVAEKRQLVYKLDKKVVEASSNMMGGGGSAVDILENTPSI
                     RVDAEGDVTFRGSSGFLVYIDGKPSVFSGTQALEQVPAGHIENIEIITTPSAKHDTEG
                     DVGIINIITKKHSQRGLSGMVNLSGSTWLSRHVDFLLAQQHQRSRWYIGGQWTDRLRK
                     SDFDQEKMTVVGDQTTTSHSVGPRTGDSYHYTLKGGWSLNLPKTTIALDLEGGYGGNK
                     RKGEMNYKETRSVAGGSPVTEDYRSIDDYDNDENIGLGSLAVQHKFNDKGHELSGSAY
                     YKYGGHALEYFFNDLMSLEGQRQQGHRAYEAEHRETMRINLDYALPFGKGGKLEAGYQ
                     YYSYLEDGDYNMEWWDPKGQTFFWRDDIYNTFYFQEGVNSIYTILSHTWKNLEAQAGV
                     RGEHTHTVLRSSVEGADRTKNRFEFFPSVHLGYTFLNEHRLLASYSRRTTRPQLFYME
                     PYITYRDFYTAEIGNPDIRPEYINSFELNYRKNFGENTVSATAFHRYRKDKIERLRVP
                     YSAGVTLDSMSNVGHDYSTGIELSVSLHPVRWWNTTVNGNVYHYKVKNEQAAGGNTTS
                     STNYDILWNNLFNLGKYTRIQLDGSFVGPSVTTQGRTDAYW"
BASE COUNT         3917 a         3022 c         2815 g         3940 t
ORIGIN      
        1 gtggatgaag tattctctaa ggtagcggta gcggtccaag taccgtcatt acccttattg
       61 gttgccacgt tggatcgtaa agtaaccttt ggcatctcac gcaaagcttg gtagttgcct
      121 tcctctacgc cacgcagata gaagttatcc gatacgatct tgccattctc tgtcaacgtt
      181 aacttgacga aatgagcgct ggatacgcta gctgggaaat ccagtttcat acatttgttg
      241 gtagtatctt ctttactatc cacggaaacc tcgttttccc atgaaataga accgtccata
      301 ttgatgattt gagcctttgc cgtcaaacca ttacgtacgc cggcgctata gttcactacc
      361 tcgatctcgt ccgtaaccgg attccattga atgtgcagag gctcggaggc cttcttgcaa
      421 ccaaagtaag cggcggtagg ctcgaaataa taatcgtaag tctgccatac catagaaggc
      481 catgccggat gcgtcatcca cagcaataat cccttacggt tcaagcttct tgattcgaac
      541 ataccccggt aaccatcata gtttacccac tgagccagat cggcgaattc cttggcgttg
      601 ttcggcttac cgaagccctt ttcgatgata gcgttgaaag aagcgcaaga ctgggcgcct
      661 tccatcgtat aatcgtgttg tccccattga gcgttttgcg gccaaagcgc ttccggagag
      721 aaagtacgaa ccaagctctc gtaattcatc acgttgggca taccccgctc actatggaac
      781 ttatcactac cattcttcaa gctaaagtat tctttaacag gaagcgcacg gtacgggcca
      841 tggccactta ccacctcatc cgccgagctg gagatataat gtaagcccgg atgatcctct
      901 ttcacgatac ggcgtaaagc cttgtcgatc tgctccggcg ggaagccctc gttgcgcccg
      961 caataaatac cgatagaggc atggttacgg aaacgtttca cataatcctc agcattggcg
     1021 ataaacatct ccggatcata aggatcgggt ccgtcggaag gattcgccaa ccagaaatct
     1081 tgccagatca tgataccatg acggtcgcaa gcctcataca attccttgtc gccgatttgt
     1141 cctacccagt tacgcatcat cgtaaagttc atatcagcat ggtaagccac ggcgatgtcg
     1201 tactcacgac cccggtaatt cagattagac tcaccaaatc cccagttacc gccacggcct
     1261 ataaaacgac gaccattgat aaagagactc aagatactat tattctcatt gaaggtcatt
     1321 tgtcggatac ctaccttgaa atcctcagag tcggatacct tatcgcctac cttaaaggtg
     1381 aaattagcgt cgtataaata aggagatccg taccctttag gccaccacag acgtgggttc
     1441 tgaaccttca attggctgaa gctatttgga tcgaaagtaa ccgtcttctc ctcgtttgcg
     1501 gccaattcta ccggttgctc gaaagtgata tcgccgatct ttcctgtcaa tacacccttt
     1561 actggagcgg catcatggtt cttcacgatc acttccggag tcaaggtagc ggaagtcgta
     1621 tccggcaacg gtaatacaac ctgtacgaac gggtcttgaa tcgttacctt gcctgtagaa
     1681 gtcaagtaca catcatccca aatacctata ttacgaccac ggatcgtcga gatccaatcc
     1741 caaccgatcg aagcgtggaa ggttgggtta tcagcgccta agataccacc gttgaaatcc
     1801 gtattcttct cacatttctc cttgatagca ccgatatgct cattcttgat gatctccacc
     1861 gcgacaacgt tcttacccgg tacgaccctg tctgtaacgt caaatacacc tcggataaac
     1921 gctccctcga tacggccgat cttgttaccg tttaaatata cattcgcttt ccagttgata
     1981 ccatcgaaat tcaagaacaa acgatcttgc ttgaatcctt cgggtacctc aaactcatcc
     2041 ctataccaga aattagagtt gaagaatgac tcggatatct gcatcaggtt atccgcgtaa
     2101 ttcggattcg ggatagctcc gatattctta taactactca ataccgttcc cggcacagtc
     2161 gccacgatcc aattttccgg agagaaagaa ggtttcgata tttcctcacc ggaagcggtt
     2221 acctcggaag ctcgttgtac tttccagttt ccgcccgaca aacggatctc gtcttttgta
     2281 gcagctggag cagcagccgg ttgggcaagc aagccacctt tacccatcac ctctatctcg
     2341 cttaagatat agcgtccgtc attagccggt tgctccatcc atacccgtac gtagcggcct
     2401 tttcctttta gcttgatctc atccagatta gcatctccac ccggaagatt cgctatgtca
     2461 acccattgtt tagcgtcgtc ggaaacttga atcttaccct tgatcgcttt attgatccaa
     2521 tgtaatttta ctttgtcgaa ttcggattgg ctacccaagt ccacatagac ccactcctct
     2581 cctgtcgtgg cactcatcca agcgctatta aagaatttgg aaggaagcaa atctatcaac
     2641 ttatcttggt tatagaaatt catctcgaag aatgcccaat aagcggcacc ttccattttc
     2701 aatcgcatcc gataataagc atattcaccc ggttgatcga atgtcaaagt ctcattcaac
     2761 atacgggtgg gcaacgtacc cggatcccag ctattcttgt tcgggtctga atgggcctta
     2821 tacttgctgg ccttacccgg cataccttta tcctttaagg cagccaattc cgtccaagta
     2881 tttccatcat tcgatccctc gcaaacaatc tcatatccat ccttaatctt attctcgtca
     2941 taagccacgc tgccgcggaa ttgtaccttg tcggctttct ctttccagtt attcagcgtg
     3001 aacaagaaat aggcatcctc tcccgtaacc gcattacgag aataaggacc ttgatcgatc
     3061 atccactcac gctcacgacg agctatatcc ccattttgcg tggagagatc gagatactga
     3121 ggttgtttat cgctaataac accatccgtc accagttggg ccgttagatt gtaatcataa
     3181 ctggatgagt tgtaagcgct acgcaaaaga gctatgttac gatacgtgga ataatccgga
     3241 cgtaatgaag gagaaaaatc ctcccccgga tctcccggat acgaaccgat acctctggta
     3301 taataatccg accgatcgaa agattccgcc ggaacaccgc tctgcccaca tcctcctagc
     3361 aatgctgaga ccgctaccgc tccacaaagc gtcaagagtc gaggcaattt tttcttttta
     3421 ctgaatgttc tcatactact tattgtgttt ctctaaatta gttagtttaa taagataccg
     3481 tcacgtcaaa accctccttc cgggcccgtt ccgcaatcgc atctaattct tctttagtag
     3541 cttttttcaa agctttaacc ggggtctccc tatctatcgt ataaatcatg acttgtttcg
     3601 gacggatttg ttttaaggcg gagatccagc ccgctatctc ctcttctgtc atattattaa
     3661 ccgatttccc atttacttcc cccttcaaga acatggtctg tataatcaag tttccgttaa
     3721 aacgacataa ttgctttaat aaagactcga aattaaacgc cggagaatta ggtacgtcta
     3781 tctgccgaat ccgactgtct aatacagaat ccagtttcaa tatgttatcc tctattttat
     3841 tcaaggcttg aaagacctcc tctttctgga gcatcgtaga attagaaagt acggcgattt
     3901 tagcatcagg gaaaaatcga tcccgggtag cgatcgtatc atcaatgatt ccaccgaatt
     3961 ccgggtgtat cgtaggctct ccgtttccgg cgaatgtaat tacatccgga gcgatccctt
     4021 ccgctttcat ggaacttagt ttttgctcta aggcttccct cacttccgta cgagtaggca
     4081 gtttactatg ggtcctatga ttctcattca atccacattc gcaataaatg caattaaaag
     4141 agcataattt cccgtctgta ggaagtaaat tcatccctaa agagacacct agacgccgac
     4201 tatgtatcgg gccaaatact attttatcaa aaagaattgt agacatagcg ctgtttgttt
     4261 ttacccacgc aaatctactc taaaatttcc agcgaagcaa agcataaaga tctgttttat
     4321 cagaaccgct tatctcctcc gtatcagtac ctatcaaatc cctgtcccaa taatgggtgt
     4381 gagccagttt cgcagacaag gataaacgtt tccaaatatc cagacgaaag gtaagggcaa
     4441 accgcatccc atccccataa aaagagggca tattaaaggc atataatata ttcttctcat
     4501 acgaactgac ccggctattg taatcatccg tatgaaacca cgctagataa ccatctattt
     4561 gaagaggtag ggtagtgggc ttccagccta tactttggga gatcataatt cctttattaa
     4621 gtttctttat aggatcatcg aatagaatac catctaagga agtcttaaaa ataaaaggag
     4681 aagaaaagtt ataaacctgt tgaaaacgaa tacgatgttg tttataagta ttgattttca
     4741 ataaattatc attttcaaaa gttccattct tttctttttg tcgatattta taacgaagat
     4801 aagctgaata gtttctacta ggggtataat ctatctgagc catatattcc tgtcctccgg
     4861 aaggagcgtc tatcccgtat ttcaaccaag ggaaacggaa taagtccgca taaacggata
     4921 atttccagcg ggcgatcggg gttaattgca atcccatata aaccccttgc tcattctgaa
     4981 ccgtagagcc ttgcgagaaa gcgttcccaa acaaagcttg ataacggcga tcgtaatagc
     5041 ggtataatac caagaaagat atataagaag cgggtgttaa ctgcaaggca ttcaaggtag
     5101 aaatagctcc gtttttcgaa agggcagttt cgccataaaa cttgatacgg ttacttttca
     5161 acatatagtc aacaccgatg ttgaaattgt tggaacctct gaaatagaac aaattataag
     5221 gttttggatc ggggtcaatg ttgaacttac cgaatgaata ggagagagcc gttaaaccta
     5281 catgaaaatg agatgtagca tagcggatat ttcctccata tacctgcatc gttatcattt
     5341 tcctcttttc ccaatcccgt tgtaaacgat gaagtccatc cgtttttaat gaggtgaatg
     5401 tcaagctatc tacggccgca tccattttcc ggtacgaata gaaaacactt atatccaagt
     5461 ttttaatcgt gatcgtacta gccacccctc ggaagaaatc ctgttcattg gttgagaagt
     5521 gcctacggaa gccatttgtc cttcgctccg cttgagcgac tactgccgta cgactaggag
     5581 aaaagtcatt gctaatcacc agaccttgtc cgaaagacat cttgtaatcc cctatagcca
     5641 agctttttaa ccagttgata tcttttagga atagatgtgc ggaataaaag tcatatcctt
     5701 tatgatatgc gttccaaaaa ggttcgcccg catctttctc agctacgaag cctgcttgta
     5761 aacgatcctc gaaagtatag gaataacgta aggagtgata gaagggttct cctctatatt
     5821 tacgattcgg atataacaaa agtatgctgt ccgtttgttc accatatccc tttttctgtt
     5881 gaaaacattg atcatacctg atttgtaatt cattatgacc atatttcaac aggttcttaa
     5941 ccgtaagcaa ccgtttttca acaagattat cacctatata aacaaatgga aggagaagag
     6001 atatcgtctg aaaatcgata tcctctatat tcttcaactc atagatgcta accatatttc
     6061 cgtatcgttt ccgataggag aggagctgct caatttggcg atcggataga aaaggtaatc
     6121 gcttcagttg ttcttccgtc acggcattca aatcaaaagg atgctcaatt aaataagata
     6181 aatcggcata caaactttct atacgctccg tatcctcggt ttccaaggct agttcctcta
     6241 catactccat ccacttatca acagaatatt ctatttgaga attagcgtaa taactattta
     6301 tcaacaggat tatcgacaag attataaaca atcgtttcat agctaagtat catttaaaaa
     6361 gagaatgata aaccaagact ggtactcatc cctaaaatcg gatggtaaat agaggctaca
     6421 tctatcgtaa agcaagaaaa gttataacca attcctaaag agggcaggag aggagcggtc
     6481 tgtattccgg cacgaataaa aaaagaatcg aaagcggtgt attcaagacc taagtttcca
     6541 acaactaggt tttcattttc cgttcctgca cttcctgtaa ttaacagact gtttataatc
     6601 tcccattgaa aacttatttg aattaagtaa taattaaaat cttctatttc aatatcttta
     6661 tctcctatag aaacagatgg taaattcatt attaacattc ctattaacaa cttatcaata
     6721 ggagagaaag tgattccaag atctgttgac agtctggatc ttgtattttc caatagatca
     6781 gtttgcaaga aactatagtg aactccaagc cctaacgccc attgatcccc caagcgtttt
     6841 cctcccagca cacgaaccat catctccctg tacttatcaa acccgaaaac agagatatca
     6901 acacctgcgg ataatagttg attcggataa taaaaactac cggacatcgt acccagttct
     6961 ttcaacatgt accgattaaa gtattctaaa tgaatggatt ttttatcttt atcgacaata
     7021 agggccggat tgaataaaat agattgcgtc gccacattcc ctcccattcc cacgctacga
     7081 acatccggta aacgtaagtt atcaacacca tgtacataca atgaaaatac ccccgcaaac
     7141 agggatagca atagatattt catagttaag attttgtatg gtttctattt attcttcaag
     7201 tttttcttat tatccttatt tatcctacgc tgtacctttt taatatcctc attaggagaa
     7261 agttgttcag gcttaatccc cctttgcaat aacatatcac gtacagcagt attgttatca
     7321 atatgttctt tttcaatagg agattgtcca tatagatcct tcgcttgcac atttacgttt
     7381 gtcatttcag tcgctaggtc tttagctttt atacttatag tcggtaaaaa atcagcgata
     7441 ggtctattcg tggggacgtt cattctcttt ttcaacatct gtgtacttaa attgaataaa
     7501 gcttgatctc ccttagaacg aataatcgcg aatcctttat tatcaatacc tctttcgtat
     7561 aagattccag ataattgttt ttcagtctga ctcaattttt ccctggcctt taagcgttca
     7621 caatccaata gacgttgctc aatcacctcg gccttacggg tttgtaccgc aaaataagtc
     7681 tgtgcgaaag cgacttgtgg tttacggcta tcaccatttt gtgcgattaa atagcatgcg
     7741 tagcgtgtta ataagatgtc atctatttgt ttttcaacac cataacctat tgaaaccatt
     7801 ttcccgacat cgggaaaatg gttttgtaca tcttctcccg cattccggca cgcttctttg
     7861 gctttcacca ctacattatt gataaagtta tcccatttgg catatcctaa taggggttgt
     7921 aactctctgg cactccagca ttctatgcct tctacctcac atgaaatgga ttcgaatttt
     7981 ccgaataggg cggtaatttc ttctttcttc atagttaata tattcttaag ttgttgtcaa
     8041 ttgcgcaaat gtaatgtttt atattcattt agcaagttat taacagataa atgatgctga
     8101 gagtcacgca gtatttatat tttcgcggta tatgatacga aaagggatat attgtatttt
     8161 ggctctactc gctctctgta gctttaaagg gatggcgcag gcggtaaaga caaatattgt
     8221 tccggaaggt tatcagaaag ctcaactgta tgaaggtgat acaatggctg tcgtcaacct
     8281 tcgggaagtt ttcatatatc ctcaagttaa gtttaagaat aagcgtgaac aagcgaagta
     8341 caataagttg gtacgagacg taaagcgtac tttgccctat gccaagatgg tgtatgatac
     8401 gttgatagag acctacgaat acatggaaac cttaccgaat gacaaggccc gccaagccca
     8461 cttgaaacgg atggagaaag agttgttcgc ccaatataaa ccggaactaa aaaaattatc
     8521 cttctcgcaa ggtaagctac ttatcaaact gatcgatagg gaatgtaatc aatccagtta
     8581 caatttattg aaagcctatc tgggaagttt ccgtgcgggc ttttggaatt tcttcgccgg
     8641 aatgttcgga gccagtctga aatcggaata cgacccgaaa ggtaaagatg ccatgaccga
     8701 acgggtcgtc gtattggttg agaatggttt aatctgatag ttgcttgaag aaatcccaga
     8761 tcacgatacc ggtagtaacc gatacgttca aggaatgctt tgtaccgtat tgaggtattt
     8821 caatacatat atcacagtta tcaaccacat tttgttgaac gccttttacc tcgttaccca
     8881 tgacgatagc gtatttcttt gttttgtcta actgcaagtt atctaacatg acactacctt
     8941 ccgcttgctc tacggcacat accgtatacc cctcttggcg cagtttatca acagcctccg
     9001 gggtatcctt gaaatattcc caatctacgg tttcttccgc tcctaaagcg gtcttatgga
     9061 tctccgcgtt cggagggcaa gccgtaatac cacaaagata aatagcctct acccggaaag
     9121 catcggaggt acgaaacacg gaacccacgt tgtttagact tctaacatgg tctaaaacaa
     9181 cgattaaagg tatcttctta ctttccttaa aagcctcggg agtcaggcgg ttcaattcgg
     9241 ttacttttaa ttttcgcata acaaatatct ttgaccgcaa aagtagcgaa tatccgtgga
     9301 tatgccgttg aaaagctatt aataagtagt ggacataaaa tgaaaaatat ttcttgcttt
     9361 attcaaatac ttgtccatac cccccccttt ctcaaattag caaatgaata agccacttat
     9421 ttattacgcg ctatcaacag cccttataca cctattgaca gccttgctgg aggatctatt
     9481 ttttcacaat caaggttatc aacaataaac agctaaatat tcataaagtc tataactata
     9541 agaattacaa tctatagata gacatccatg ctgttggtat ccttttgata aaccgttcac
     9601 agactttaat aagtcaataa ccaaagattg taacaaaaat gtattaacca tttcaacagc
     9661 ctatcatatt catcatattt atttttaaaa ttaaagatta ataagaatat aatataatga
     9721 ttgtggataa ctcttgatgg ttcacgacag ctcatccatc gacagcaaag ataagaatct
     9781 ttcttgttat ttctataaat gaagaaagtt tatacctttg tgctttgtga acaataggtt
     9841 gataaactag ataagatgaa gattatcagt aatactttct gtggataata ttgtttatat
     9901 atagtgaaaa gcctattggg agcagtagaa acaggaatca ttaatatata aggctatgtt
     9961 gacaaaccaa tcaatcgggt acatggatgc gcccgttcct aaggatttag accttaagga
    10021 agcgatcgac aagttacgta aagagaagaa tgcgattatt ttggcgcatt actatcaaac
    10081 aggcgatata caagatatag cggactatgt gggagacagt ctggccttgg cacaatgggc
    10141 ggctaagacg aaggcggata tcatcgtgct ttgtggggtt cactttatgg gagagacggc
    10201 gaagatcctc tgcccggata agaaagtgct ggtaccagac ttgaatgccg gttgctcctt
    10261 ggcggatagt tgtccggcta cggagttcgc cgagttcgtc aagcaacatc ccggtcatac
    10321 ggtaatctct tacgtgaata cgaccgccgc cgtgaaagcg gtcacggatg tggtggttac
    10381 ttccacgaac gcccgccaga tcgtggagag cttcccggaa ggtacaccga tgattttcgg
    10441 tccggatcgt aacttaggta attatatcaa tagcatcacg ggacgtaata tgttgctttg
    10501 ggatggcgct tgccacgtgc atgagcaatt ctcattggag aagatcttat ctttgaagaa
    10561 acagtacccg aacgcggaag tgatcaccca tccggaatgc aagcagccgg ttatacaggt
    10621 ctcagacttc gtaggatcga ccgcggcttt gctgaagcat accattaagt ccgacgcgaa
    10681 acaattcatt gtagcgacgg aaagtggcgt tattcacgag atgcgcaagc agagtccgga
    10741 taaggaattc atcccggctc ctccgaacga cagtacttgc gcttgcaacg aatgtaattt
    10801 catgcgcttg aacacgatgg agaagctata taattgcttg aagttcgaga tgccggagat
    10861 attcgtggac aaggaagtac agaagaaggc catcaaaccg atcaagaaga tgttggagat
    10921 ctctgagaag ctgggactct gatccaaaca aatgcgggat aggtctcaac cgataggccg
    10981 gacttgagtg atataaaagc taagcccggt ctattatatg taaataatca aaattatgta
    11041 caatatctac aactatcctt ataatcattt gattttaaaa tatttatcct attgttgtag
    11101 ataggaaaac atctacaata gtaagtcttt atctaccatc atttcccgct tttagtaagt
    11161 gtctttgcca tgccgtcaaa ggaattttct acactctacg tatataatca gtccgttttt
    11221 cttcctttct ttatatagat aaaatattaa tatataagta tttgtggttt tttatggtat
    11281 aaaacaaaag ttttacacat aggaaacatt tgttttcata gaagaaaact aaagttttgt
    11341 actgaagaaa cttctgtttt cccatgtaga aacttttgtt tccctaggaa gaaaccattt
    11401 gcttcgctac tcgaactcgg acgatcccgg gaaagaatat atcaagaatg atcgctatta
    11461 attaccgtaa cattctgaat ttagttactt ttgcgtagaa atctaattgt aattctcaat
    11521 atcatgaaaa agataggact aatgttggcc ttattatggg tgatttgtgc gctctcgtgg
    11581 gcttcttctc cggatgcccg tattaagggg cagttaatag atgcctctac gaatcaagtg
    11641 attaattatg cggatatatt tctgtttacg atgggaagtg aaaaaccttt gcaacagact
    11701 tttccggacg atcaaggacg tttctcgttt actaaggtgg ctccgggtaa ttatgtggtc
    11761 atggtccgtc tgatgggata tgatgtgttt acaaagaatg atatcatctt ggatgcctcg
    11821 tctccggtgg atttaggtaa gttgatgatg agtcccttgg aggtaggtat cgccgaagtg
    11881 gaggtagtgg ccgagaaacg ccaattggtt tataagttgg ataagaaagt ggtcgaggcc
    11941 tcttccaata tgatgggagg aggcggttcc gccgtggata tattagagaa tacgccttcc
    12001 atacgggtag acgcggaagg cgatgttact tttcgtggaa gcagcggctt tttggtttac
    12061 atagatggta agccgagtgt cttctcgggt acacaggctt tggagcaagt cccggccggg
    12121 catatagaga atatagagat tatcacgaca ccttccgcca agcatgatac ggaaggcgac
    12181 gtgggtatca ttaatattat cacgaagaag cattcccagc ggggattgag cgggatggtg
    12241 aatctctcgg gaagtacgtg gctttcccgc catgtcgatt tcttgttggc acagcaacat
    12301 cagcgttccc gttggtacat cggcggacag tggacagacc ggttgcgcaa gagtgatttc
    12361 gaccaagaga agatgacggt ggttggcgat caaacaacga cttcgcattc cgtcggacct
    12421 cgtacgggag acagttacca ttatacgctg aaaggcggtt ggagcctgaa tcttcccaag
    12481 acaaccattg cgttggatct ggagggcggc tatggcggaa ataagcgtaa gggagagatg
    12541 aactataagg aaacccgttc ggtagcgggc ggctctccgg tgacggaaga ttatcgaagc
    12601 atagatgatt atgataatga tgagaatata ggtttgggaa gtctggcggt acagcataag
    12661 ttcaacgata agggacacga gctttccggt agtgcctatt acaaatatgg cggtcatgcg
    12721 ttggaatatt tctttaacga cttgatgtct ttggaagggc aacgccaaca ggggcaccgt
    12781 gcttatgagg ccgagcaccg ggaaacgatg cgtatcaatc tggattacgc cttgcctttc
    12841 gggaaaggag gtaagctaga ggcgggttac caatattatt cttatctgga agacggcgat
    12901 tacaatatgg aatggtggga ccccaaggga caaacgttct tttggcgtga cgatatctac
    12961 aacacgtttt attttcaaga aggggtgaat tcaatttata cgattctttc ccatacgtgg
    13021 aagaatttag aggcgcaagc cggcgttcgg ggagagcata cgcatacggt cttgcgaagt
    13081 tccgtggagg gagcggatcg tacgaagaat cgttttgagt ttttcccatc ggtgcatttg
    13141 ggctatacgt tcctgaatga gcatcgtttg ttggcttcct attcccgtcg taccacacgt
    13201 ccgcagcttt tctatatgga gccttatatt acgtatcgtg acttttatac ggccgagatc
    13261 ggtaatccgg atatacgtcc ggagtacatc aactcctttg aattgaacta ccggaagaat
    13321 ttcggggaaa atacggtatc cgctaccgcc tttcatcggt atcggaaaga taagatcgag
    13381 cggttgcgcg taccttattc agccggtgta accttagact cgatgtcaaa cgtaggacat
    13441 gattattcaa caggtatcga gctaagtgtc agcctgcatc cggtacgttg gtggaatacc
    13501 acggtcaacg gaaacgttta tcactataag gtgaagaacg aacaggccgc cggtggaaat
    13561 acgacctcaa gcaccaatta cgatatccta tggaataacc tgtttaatct ggggaaatac
    13621 acccgtatcc aattggatgg tagttttgta ggcccttccg taacgacgca gggccgtacg
    13681 gacgcttatt ggta
//
LOCUS       DBMDTB010000102        13249 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_1425_length_13249_cov_13.955735, whole genome shotgun
            sequence.
ACCESSION   DBMDTB010000102 DBMDTB010000000
VERSION     DBMDTB010000102.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 13249)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 13249)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13249
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1425_length_13249_cov_13.955735"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            225..1625
                     /gene="fumC"
                     /locus_tag="ACZPB4_13880"
     CDS             225..1625
                     /gene="fumC"
                     /locus_tag="ACZPB4_13880"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045239 - tricarboxylic acid cycle
                     heteromeric enzyme complex [Evidence IEA];
                     GO_function: GO:0004333 - fumarate hydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006106 - fumarate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fumarate hydratase"
                     /protein_id="HIR1099339.1"
                     /translation="MKYRIEKDTLGEVEVPVDVYYGPQTQRSVNNFKIATDISRMPKE
                     VIEAFAYLKKGAALANKDAGVLSPEKCELIGKVCDEILAGKLNDSFPLIVWQTGSGTQ
                     TNMNVNEVIANRAHVLSGGKLTDKEKVLLPNDDVNKSQSSNDTFPSAMHIAAYKVTAE
                     VTIPGLESLYRALALKSEEFMKIVKIGRTHFMDATPLTLGQEFSGYAAQLEYGIRKVK
                     DSLSHISELALGGTAVGTGINAPVNYDECVAKKISELTGLPFVTAPNKFEALATHDAL
                     VEAHGALKSVAVSLMKIANDIRMLGSGPRAGIGEIHLPENEPGSSIMPGKVNPTQCES
                     LTMLAAQVMGNDVTISIAGSNGQFELNVFKPVIISNFLQSARLIGDGCLNFSERCVKG
                     ITPVNENIKRHLDSSLMLVTALNPKIGYYKAAAIAQKAYQENKTLREAAIESGYVTAE
                     EFDRWVDPSKMVGEIE"
     gene            1720..5163
                     /locus_tag="ACZPB4_13885"
     CDS             1720..5163
                     /locus_tag="ACZPB4_13885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-rhamnosidase"
                     /protein_id="HIR1099340.1"
                     /translation="MKSTRCILSIILGLLAGWLPLGAVTVLKNLQVEYQTNPLGIDVS
                     QPRFNWQMESDRYGACGQAYRLWVADSPEQLAAGRYIYDSGKVLSGESVGVVYQGKAL
                     QPSTRYYWKVSVWDESGTEITSTEPAWFETGLLGSGWSGARWIGSSETQLSKYRSHYV
                     IDYDVRVAEGNDKAVFVFGARDADNYVSAELDLNGSGDARFILRHTTDGKTRQDAAES
                     LASIIPASDKHKVHHIRLKVTTAQYALKYFVDIEIDGKTLVNSSLTPEEKERKSRGDF
                     WGGKEGAFTVYPYPDGELVYHCRLYAIGFLQPKGQTATFSNLRISEDTWNTLLYNPAE
                     TYVEKGEGKLNVWYPGENVSAPMLRKAIKIEKPVKSARLYATARGVYEFSVNGRKVGK
                     DYLNPGWTDYRYRIMYNTYDITSLLRPGDNGIGAMLGAGWWSEHSGFLTGWQDQYGTR
                     QSLLGKIVIEYADGTRETIVTNDSWKCYDRGPITFNGLQNGEEYDARKEVNGWDAPGF
                     DDSSWKPATLFAAPPVNVEIQGYVGSPIQNNVTLTAQSMVEPIPGVYVYDMGQNMVGV
                     PRLTFKGKAGQEITIRFGEMNYPETIPTEPVAPYTIAMYKEKKGQVYTDNYRSALSTD
                     RYILRGDAAGETYEPRFTFHGFRYVEIHGLDKPLPLEAVKGIVLESIGAQTSGYETSD
                     ERVNRLFNNIIWGQRGNFLSVPTDCPQRDERMGWTGDAQVFARTATYNMNVDPFYTRW
                     LYSVRDNQGDDGSYANYIPVVGFPPHGAEDGGGAMGWMEAGVIVPWQMYQQYGDVRIL
                     EQHYASMVAYMDYLERRAVRYVQPFGGFGDWLAIEPTNSMLTNTAYSAYDALIMEQVA
                     KRLGKDADQRRFRTFYENVKRSFNDLFVNEEGRTFAPTVESIFGKDSQVGMWPGTAAT
                     EAKIVDTQTSYVVPLQFDLFNEKNKPLAIRHLVENIKKHNYTLTTGFIGTPYLNLVLS
                     DNGYDDVAYKLFEQTAYPSWLYPVLQGATTIWERWNSYTLVNGFGPVDMNSFNHYSYG
                     AIEEWMIAYTLGIQRDEEQPAYKHIILQPRIGGTFSFIRGHYDSAYGRIESGWQIQKK
                     GYIYEATIPANTTAILYLPAKSEKSVRMEKGQEGITLVGLKDGKAVYRLRSGSYRICV
                     D"
     gene            complement(5392..>5602)
                     /locus_tag="ACZPB4_13890"
     CDS             complement(5392..>5602)
                     /locus_tag="ACZPB4_13890"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099341.1"
                     /translation="LIYFCANVQILIRPGTIVFTKSDLTPGEKRRISPRFDLAPGVNP
                     AFLTDSTAHPAQGQIFLQDSTPHPM"
     assembly_gap    5603..5702
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            5846..7234
                     /locus_tag="ACZPB4_13895"
     CDS             5846..7234
                     /locus_tag="ACZPB4_13895"
                     /EC_number="7.5.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine ABC transporter ATP-binding protein"
                     /protein_id="HIR1099342.1"
                     /translation="MSIRKSDRIISVEHVSKYFGEKAVLNDVNLQVRKGEFVTILGPS
                     GCGKTTLLRLIAGFQTASEGVITMSGKEITQTPPHKRPVNTVFQKYALFPHLNVYNNI
                     AFGLKLKKLPSATIEKKVKQALKMVGLTDYEDRDVDSLSGGQQQRVAIARAIVNEPEV
                     LLLDEPLAALDLKMRKDMQMELKEMHKSLGITFVYVTHDQEEALTLSDTIVVMSEGKI
                     QQIGTPIDIYNEPVNSFVADFIGESNILNGTMIKDRQVSFAGHEFECVDEGFGEQMPV
                     DVVLRPEDIYIFEPSEAAMLTGTVTSSIFKGVHYEMMVQTPNGYEFMVQDYHPFEAGS
                     EVGLLIKPFDIHVMKKERICNTFEGKLIDATHVEFLGCTFECKEVTDIEPNTPVKVEI
                     DFKDVILEDNEEDGRLTGEVKFILYKGNHYHLTVFTDWDEDIFVDTNDVWDDGDHVGI
                     TIAPDKIRIIHA"
     gene            7247..8044
                     /locus_tag="ACZPB4_13900"
     CDS             7247..8044
                     /locus_tag="ACZPB4_13900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1099343.1"
                     /translation="MINTFSAFFMRRRNWTIPYVLFLAIFVVIPLLLIVYYAFTNDEG
                     MFTFANFRKFMIHPEAINTFVYSVGIALITTILCLLLGYPAAWILSQARFNTSRTMVV
                     LFILPMWVNILIRTLATVALFDFLNFPLGEGALIFGMVYNFLPFMIYPIYNTLQKMDH
                     SLIEAAQDLGANPSQVFVKAVFPLSMPGVMSGIMMVFMPTISTFAIAELLTMNNIKLF
                     GTTIQENINNGMWNYGAALSLIMLLLIGITGLFSNESSDSANEGGLI"
     gene            8044..8832
                     /locus_tag="ACZPB4_13905"
     CDS             8044..8832
                     /locus_tag="ACZPB4_13905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1099344.1"
                     /translation="MVKYLAKGYLWALLLLLYSPILIIMIFSFTEAKVLGNWTGFSTK
                     LYSSLFAGNVQHSLVSALWNTFAIAMIAATVSTLLGSVAAIGIFNLKARARNAVSFVN
                     NIPMLNPDIITGISLFLLFVSLGISQGLTTVVLAHITFCTPYVVLSVMPRLKQMNQNI
                     YEAALDLGATPFQALRKVIFPEIRPGMISGFILAFTLSIDDFAVTIFTIGNEGLETLS
                     TFIYADARKGGLTPELRPLSTIIFVTVLVLLIVINKRAEKAKRA"
     gene            8839..10176
                     /locus_tag="ACZPB4_13910"
     CDS             8839..10176
                     /locus_tag="ACZPB4_13910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HIR1099345.1"
                     /translation="MKKFISILSVLALLMGLFTSCERSDEERSKILKIYNWGDYIDED
                     VLTDFPKWYKEQTGEEVRIIYQVFDINEIMLTKIERGHEDFDLICPSEYILERMLRKN
                     LLLPIDRNFGKTPDYINNVSPYIQAELNKLSQPGRKTTDYVVPYMWGTAGLLYNKADV
                     SRDEVMSWKCLWDPRFRNKILMKDSYRDAYGTAIIYAHARELADGTFTVEQLMNDSSP
                     EMIAIAEEYLKKMKPNIAGWEADFGKEMMTKGKAWLNFTWSGDAVWAMEEASAVGVDL
                     GYEVPLEGSNIWYDGWAIPKYARNVKAASYFMDYLCRPDIVSRNMEVTGYVSTVATPE
                     ILAEKIDTTQTEFSDVSYFFGPGAERVQIDPAQYPDRKVVERCAMIRDFGNETEVVLE
                     MWSRVKGDNLNSWIVILIFAVFGLLFVWVVYKRINRYQQKRRHRRRRSWYKKK"
     gene            10178..10792
                     /locus_tag="ACZPB4_13915"
     CDS             10178..10792
                     /locus_tag="ACZPB4_13915"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HIR1099346.1"
                     /translation="MEGIKNLIIDLGGVLINLTRNRCIEAFENLGVENIREQITNNYQ
                     HKDLFERLELGTISVEQFRDDIRALSGKPLTDEQIDTAWIAMLGDVPENKLRLLLELR
                     ERYNTMLLSNTNELHWKWSEDTYFSYQGLCAQDFFHKIYLSYELHMLKPNADIFEYVL
                     KDSNLLAEETMLIDDASVNCRAAELLGMKSYMPQQREDWSHLFK"
     gene            complement(10818..11498)
                     /locus_tag="ACZPB4_13920"
     CDS             complement(10818..11498)
                     /locus_tag="ACZPB4_13920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004321442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0160254 - tRNA queuosine(34) biosynthetic
                     process from salvaged queuosine or its precursors
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="queuosine precursor transporter"
                     /protein_id="HIR1099347.1"
                     /translation="MQKTVTVPFMLLGILFNICLVASNLLETKVVQVGSITATAGLIV
                     FPISYIINDCIAEVWGFKKARLIIWSGFASNFLVIAFAQLAVLLPAAPFWEGEEGFNF
                     VFGMAPRIAVASLIAFLAGSFLNAYVMSKMKIASNGKNFSLRAIVSTLIGESADSLIF
                     FPIAFAGLIPAGELLIMIGTQAVLKSLYEVIILPVTIRVVKYIKKVDGNDVYDLGTSY
                     NILKVKDI"
     gene            complement(11560..12222)
                     /locus_tag="ACZPB4_13925"
     CDS             complement(11560..12222)
                     /locus_tag="ACZPB4_13925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2490 domain-containing protein"
                     /protein_id="HIR1099348.1"
                     /translation="MKNTSYTKRSIYLILFFIIGCTSSLYGMEGAGVYFKASLCGKIY
                     KHLSFLVEEDIRPRDDFKEAEWFLTTVEVNYKFNKYLLAGSGYMSLARYKASDELRNR
                     YYLYATGTYSAGRFTLSVRERFQSTYKVHAEHPKNYLRSMLTLSYKIGKSGFCPFAYT
                     EVFNDTRNKMRSDKIRFSTGSNYQLNPNNNLQLYYRYHIFNVDDPVNYRHAIGICYTH
                     RF"
     gene            12336..13217
                     /locus_tag="ACZPB4_13930"
     CDS             12336..13217
                     /locus_tag="ACZPB4_13930"
                     /EC_number="5.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxypyruvate isomerase family protein"
                     /protein_id="HIR1099349.1"
                     /translation="MENISRRTAIKTFLAGGVALATTGIEAVAAAKKKTDVKEPLKGN
                     VRHSVSKWCFGDYKLDEFCEICKHIGIESVELLDPVDWPIVQKHGLTVAMAQGAGLGI
                     DRGFNDPALHDELVASYEKVIPMVADAGLTNLICFSGRRNGVTDLQGWENCEKGLKRL
                     IPLAEKHKVVLTMELLNSVGHKDYLCDHTVWGAELCRRIGSPNFKLLYDIYHMQIMEG
                     NIIENIRKYHPYFSHVHTGGSPGRAEIDETQELYYPAIIKALTETGYKGFVGQEFVPA
                     QEDKIASLEKCIRICDV"
BASE COUNT         3365 a         2778 c         3595 g         3411 t
ORIGIN      
        1 atatgtcggt atcctctttg acgagatcaa ggcccgtccc gaatacatta ttgacgagaa
       61 gaaaaactat taaaaaacat cggaggcgaa ataagccgtt tttctatgat ctgaattctg
      121 ttccatgata aatgtctttt catgatatac ttgtgatatg taacataaac aattcgatat
      181 ccggatagtt tatacataga agagattaat aaaacttatg tgtcatgaag tatagaatag
      241 agaaagatac cttaggtgag gtggaagtgc cggtggacgt ttattatggg ccgcaaacac
      301 aacggagcgt gaataatttc aagatcgcca ccgatattag ccggatgccc aaagaggtga
      361 tagaggcgtt cgcttacttg aaaaaaggag cggctttggc taataaagac gccggcgtct
      421 tgtctccgga gaaatgcgag ttgatcggta aggtatgcga cgagatcttg gcgggtaaat
      481 taaatgactc cttccccttg atcgtatggc aaacggggag cgggacccag acgaatatga
      541 atgtcaatga ggtgatcgcc aaccgggcac atgtgctgag cggaggaaag ctaacggata
      601 aggagaaagt gctgcttccg aacgatgacg tgaataaatc gcaatcctcc aatgatacgt
      661 ttccttccgc tatgcatatt gccgcctata aggtgactgc ggaggtgacg atcccgggat
      721 tggagagtct gtatcgtgcg ttggcgctaa aaagtgagga gttcatgaag atcgtgaaga
      781 tcgggaggac tcattttatg gatgccactc cattgacatt ggggcaagag ttcagtggct
      841 atgcggctca attggaatat ggtatacgga aagtaaagga ttccctgtcg catatctccg
      901 agttggcttt aggaggtacg gcggttggga ccggtattaa cgccccggtc aattatgacg
      961 agtgtgtcgc taagaagata tcagagttga ctgggcttcc ttttgtaacc gctccgaata
     1021 aattcgaggc cctagctacc catgatgcct tggttgaggc gcatggagcc ttgaaatccg
     1081 tagcggtcag cttaatgaag atcgcaaacg atatacgaat gttgggctca ggtcctcgtg
     1141 ccggtatcgg tgagatccat ttgccggaga acgagccggg ttcctccatc atgccgggaa
     1201 aggtgaatcc tacgcaatgc gagtcattga cgatgctcgc cgctcaagta atgggtaacg
     1261 acgtgacaat ctcgatagcc ggctccaacg ggcagttcga gttgaacgta tttaagccgg
     1321 tgattatctc gaacttcttg caaagcgccc gcttgattgg tgacggttgc ctgaatttca
     1381 gtgaacgttg cgtaaaaggc attaccccgg tgaacgaaaa catcaaacgc catctggata
     1441 gctccttaat gctggttacc gccttgaatc cgaaaatagg atattacaag gccgccgcta
     1501 tcgcccagaa agcctatcaa gaaaataaga ctttgcggga ggcggctatc gagtccggtt
     1561 atgtgaccgc cgaggagttt gatcgttggg tagacccgtc caagatggta ggagagattg
     1621 agtagtgtca aaactgctac atcttctccc aaaaatgaaa caaagagtta agatgataat
     1681 ggatattttt gtaccgttat cattttaatt ctttgtatta tgaagagcac acgatgtatt
     1741 ttgtctataa tcttagggtt gctggccgga tggctacctc tgggtgcggt taccgtattg
     1801 aagaacctac aggttgagta tcaaaccaat ccactgggaa ttgatgtcag tcagccacgt
     1861 tttaactggc agatggagtc cgatcgctat ggggcctgtg ggcaggctta tcggttatgg
     1921 gtggccgata gtccggagca attggctgcc gggcgttata tctatgattc gggaaaggtt
     1981 ctttccgggg aatcggtcgg cgtagtttat caaggaaaag cattgcaacc ttccactcgc
     2041 tattattgga aagtttccgt atgggatgaa tcgggaacgg aaattacctc caccgagcct
     2101 gcgtggttcg agaccggtct tctgggttcc ggatggagtg gcgcccgttg gatcggctcg
     2161 tcggagacac aactctccaa atatcgctcg cattatgtga tcgactatga tgtgcgggtg
     2221 gccgagggta atgataaagc cgtatttgtc tttggggcga gggacgctga taattatgtg
     2281 tctgctgaac tggacttgaa tggttcgggg gacgcccgtt tcattttacg tcataccaca
     2341 gatggaaaaa cgaggcaaga tgcggcggaa agtctggcct ctatcatccc agcctcggat
     2401 aagcataagg tgcatcatat ccggttgaag gtgacgacgg cccaatatgc cttgaaatat
     2461 ttcgtggata tagagatcga tggaaagacc ttggtgaatt cctctttgac tcccgaggag
     2521 aaagaacgga agagccgtgg tgatttctgg ggaggcaagg aaggggcttt caccgtgtat
     2581 ccttatccgg atggagagtt ggtttatcat tgccgcttgt acgcgatcgg tttcctgcaa
     2641 cctaaagggc agaccgctac attctccaac ttgcgtatca gcgaggatac gtggaatacg
     2701 cttctgtaca atcctgccga gacttatgtg gagaaagggg agggaaagct caatgtctgg
     2761 tatccgggcg agaacgtatc cgctcccatg ctccggaaag cgataaagat agagaaaccg
     2821 gtcaagagcg cccgtttata tgctaccgct aggggtgtct acgagttctc ggtgaacggg
     2881 cggaaggttg gaaaggatta tctgaatccg ggttggacgg attaccgtta ccgtatcatg
     2941 tataatacgt atgatataac gagtttgcta cgaccgggcg ataatggtat cggagcgatg
     3001 ttgggcgccg gatggtggag cgagcatagc ggtttcctta ccggttggca ggatcaatac
     3061 ggaacccgcc agtccttatt gggaaagatc gtgatcgagt atgccgacgg tactcgtgag
     3121 acgatcgtta cgaatgatag ctggaaatgt tatgaccggg gaccgatcac ttttaacggc
     3181 cttcagaatg gagaggaata cgatgctcgg aaagaggtga acggctggga tgctccgggt
     3241 tttgatgact cgtcatggaa accggcgacc ttattcgccg ctcctccggt aaatgtggag
     3301 atccaaggat atgtaggcag cccgatacaa aataatgtga ccctgaccgc tcagtccatg
     3361 gtagagccta ttcccggcgt ctatgtctat gatatggggc agaatatggt cggtgttccc
     3421 cgtctgactt tcaagggaaa ggccggacag gaaatcacga tccgtttcgg ggagatgaat
     3481 tatccggaaa cgatccctac cgaacctgtc gccccgtaca cgatcgcgat gtataaggag
     3541 aagaaagggc aagtctatac ggataattac cggagcgccc tttccacgga tcgctatatc
     3601 ctgagagggg atgcggcggg tgagacgtat gagcctcgct ttacgttcca tggtttccgt
     3661 tacgtggaga ttcacgggtt ggacaagccg ttacccttgg aggcggtgaa agggatcgtg
     3721 ctggaatcta tcggtgcgca gacgagcggt tatgagacgt cggatgagcg tgtcaaccgt
     3781 ttgtttaata atatcatctg gggccaacgg ggtaatttct tgtcggttcc gacagattgc
     3841 ccgcaacggg atgagcgtat gggctggaca ggggatgcgc aggtatttgc ccgtacggct
     3901 acttataata tgaatgtcga tccgttttac acccgttggc tctactcggt ccgggataat
     3961 caaggagatg acggtagtta cgcgaactat atacccgtag tcggtttccc tccacacggt
     4021 gcggaggatg gcggaggtgc catgggatgg atggaagccg gcgtgatcgt accgtggcaa
     4081 atgtatcaac aatacggaga cgtgcgtatt ctggaacagc attacgcttc catggtcgct
     4141 tatatggatt atttggagcg tcgtgccgta cgctatgtac agcccttcgg tggtttcggc
     4201 gattggctgg ctatcgagcc gacgaattcc atgttgacga acaccgctta ctccgcctac
     4261 gacgctttga ttatggagca ggtagcgaaa cgtttaggga aggacgcgga ccaaaggcgt
     4321 ttccgtactt tctacgagaa cgtgaagagg tcttttaacg acctgtttgt aaacgaggaa
     4381 ggacgcacgt tcgccccgac ggtggaatct atctttggta aggactcgca agtaggtatg
     4441 tggcccggaa cggcggctac cgaggcgaaa atcgtagata cgcagacctc atacgtggtt
     4501 cctctccagt ttgatctgtt caatgagaaa aacaaaccct tggcgatccg gcatctggta
     4561 gagaatatca agaaacataa ttatacgctt acgactggct ttatcggtac gccttacctg
     4621 aatttggtat tatccgacaa tggttatgac gatgtcgcct ataaattatt tgagcaaacc
     4681 gcctatcctt catggctgta tcctgtcctg caaggcgcta ccacgatttg ggaacgttgg
     4741 aattcctaca cgttggtaaa tggcttcggc cctgtggata tgaactcttt caaccattat
     4801 tcgtatggcg ctatcgagga gtggatgata gcttatacct tgggtatcca gcgggatgag
     4861 gaacaacccg cctataagca catcatcctt caaccccgta tcggcggaac cttctcgttc
     4921 atccggggtc attacgattc cgcctatggc cgtatcgaga gtggatggca aatccaaaag
     4981 aagggctata tatacgaggc aaccatcccc gctaatacga cggctatttt atatctgccc
     5041 gctaaatcgg agaagtccgt tcgtatggag aaagggcagg agggtatcac gctcgtgggg
     5101 ttgaaggatg ggaaggctgt gtaccgattg agatcgggga gctaccggat atgtgtggat
     5161 tgaatattta gaaaatattt ggccttgcat cgggtgcgcg gtcgaatctg tgagaaatgc
     5221 ggggcttaca tcgggcgcgg ggtcgaatct tggagaaata tttgaccttg cgccgggtgc
     5281 gcggtcgaat ctgtgagaaa tgcggggctt acatcgggcg cagggtcgaa tcttggagaa
     5341 atatttgacc ttgcgccggg tgcgcggtcg aatctgtgag aaatgcgggg cttacatcgg
     5401 gtgcggggtc gaatcttgga gaaatatttg accttgcgcc gggtgcgcgg tcgaatctgt
     5461 gagaaatgcg gggtttacac cgggcgcgag gtcgaatctt ggagaaatgc gacgcttctc
     5521 acccggtgta aggtcagatt ttgtaaaaac gatagtgccc ggccttatta aaatctgtac
     5581 attcgcgcaa aaataaataa gannnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     5641 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     5701 nngagaaatg cgacgcttct cacccggtgt aaggtcagat tttgtaaaaa cgatagtgcc
     5761 cggccttatt aaaatctgta cattcgcgca aaaataaata agaacattgt tcatgattgt
     5821 ttaattctaa ttagatcaag cgagaatgtc aatacgaaaa tcggatcgca ttatcagcgt
     5881 ggagcacgta tcgaagtatt ttggcgagaa ggccgtgctg aatgatgtaa atttacaggt
     5941 ccgcaagggc gagtttgtaa ccattttggg gccttccggt tgcggaaaga ctaccctgtt
     6001 gcgtttgata gccggcttcc agacggcctc cgagggcgtt atcacgatgt ccgggaagga
     6061 gattacgcag acgccgccgc ataaacgtcc cgtaaatacg gtattccaga aatatgcttt
     6121 atttccacat ctgaatgtgt acaataatat cgcctttggc ctgaagctga agaaacttcc
     6181 ttccgccacg atcgagaaga aagtgaaaca ggcgttgaaa atggtagggt tgacagacta
     6241 tgaggatcgg gatgtcgatt ccctttccgg tggccagcag caacgtgtgg cgatcgctcg
     6301 cgctatcgtg aatgagccgg aggtgttatt gctggatgag ccgttggcgg ccttggactt
     6361 gaagatgcgc aaggacatgc aaatggaatt gaaagagatg cataagtcct taggcattac
     6421 gttcgtgtac gtgacccacg accaagagga agcgctgacg ctgagcgaca cgatcgttgt
     6481 catgagcgag ggaaagatcc agcaaatcgg taccccgatc gatatttata acgagccggt
     6541 caattcgttc gtcgctgatt tcatcggtga gagtaacatc ttgaacggaa cgatgatcaa
     6601 ggataggcaa gtctctttcg ccggtcatga gttcgagtgc gtggacgagg gattcgggga
     6661 gcaaatgccg gtagatgtcg tgttgcgccc cgaggatatt tacatcttcg agccgtcgga
     6721 ggcggcgatg ttgacgggta cggtaacctc ctccatcttt aagggcgtgc attatgagat
     6781 gatggtgcaa accccgaacg gatacgagtt catggtacag gattaccacc cgttcgaggc
     6841 gggtagcgag gtcgggcttc ttatcaagcc tttcgatatc catgtaatga agaaagagcg
     6901 tatttgcaat accttcgagg gaaagcttat cgacgctacg catgtggaat tcctaggctg
     6961 tacgttcgaa tgcaaggagg taaccgatat agagccaaat acgcctgtga aagtcgagat
     7021 cgattttaaa gatgtgatct tggaggataa cgaggaagac ggtcgcctga ccggagaagt
     7081 gaaatttatc ctctacaaag gcaaccatta tcatctgacc gtgtttacag attgggacga
     7141 ggacatcttt gtcgatacca acgatgtatg ggatgatgga gatcatgtcg gcataacgat
     7201 cgccccggat aaaattcgaa ttattcatgc ttaaaaaggg aaggaagtga tcaatacgtt
     7261 ttctgcattt tttatgagac gaaggaactg gaccattcct tatgtcctgt tcttggccat
     7321 ctttgtcgtg ataccgctcc tcttgatcgt gtattacgcc tttacgaatg acgaggggat
     7381 gtttaccttc gccaatttcc gtaagtttat gatccatccc gaggcgataa acaccttcgt
     7441 gtattcagtc gggatcgctt tgataacgac cattctttgt ctgctgctgg gatatccggc
     7501 cgcttggata ttgagccaag cccggtttaa tacttcccgt acgatggtcg ttttgtttat
     7561 ccttccgatg tgggtcaata tcttgatccg tacgttggct accgtggctt tgttcgattt
     7621 cttgaatttc ccgctgggag agggggcctt gatctttggt atggtgtaca acttcctgcc
     7681 ctttatgatc tacccgattt ataatacgct ccagaaaatg gatcacagct tgatagaggc
     7741 ggcgcaagac ttgggggcga atccgtcgca ggtatttgtc aaggccgtat tcccactatc
     7801 gatgccggga gtgatgagcg gtatcatgat ggtgtttatg ccgaccatct ctacgtttgc
     7861 catcgccgag ttattgacga tgaacaatat caagctcttc ggtacgacca tacaggagaa
     7921 tatcaataac ggtatgtgga actacggggc ggcgctttct cttatcatgt tgttattaat
     7981 cggaatcacg ggattgttca gcaatgagag cagtgattcg gcgaatgagg gagggcttat
     8041 ctgatggtga aatatttagc taagggatat ctgtgggctt tgctcttgtt gctctactcg
     8101 ccgatcctga ttatcatgat cttctcgttc acggaggcga aagtgttggg taactggacc
     8161 gggttctcca cgaaattata tagctccctt tttgccggca acgtgcagca ctcgttggta
     8221 agcgcccttt ggaatacgtt cgctatcgcc atgatagccg ctacggtatc taccttgttg
     8281 ggaagcgtgg ccgctatcgg gatctttaat ttgaaggcaa gagcccgcaa tgccgtgagt
     8341 tttgtcaata acatcccgat gttgaatccg gatatcatta ccggtatttc cttgttcctg
     8401 ttgtttgtca gcttagggat ctctcaaggt ttgacgacgg tcgtgctggc gcatattacg
     8461 ttctgtacgc catatgtggt attaagcgtc atgcctcgct tgaaacaaat gaaccagaat
     8521 atctacgagg cggcgttgga tttgggggcg actccgtttc aggccttgcg gaaggtgatc
     8581 ttcccggaaa tccgtccggg tatgatcagt ggctttatcc ttgccttcac gctgtctatc
     8641 gacgatttcg ccgtgaccat atttacgatt ggtaatgagg gcttggaaac cctttccacc
     8701 tttatctatg cggatgcccg gaaaggagga ttgaccccgg agttgcgtcc cctctcaacg
     8761 attatcttcg taaccgtgtt agtattgttg attgttataa ataaacgtgc tgagaaagcg
     8821 aagcgagcgt aaatgaaaat gaagaagttt atatcgattc tatctgtttt ggccctgctt
     8881 atggggctgt tcacttcttg cgagcgttcg gatgaggaga gaagcaagat cttgaagatt
     8941 tataactggg gagattatat cgacgaggac gtcttgacgg atttcccgaa atggtataag
     9001 gaacagacag gtgaggaggt ccggattatc tatcaggtct ttgatatcaa cgagatcatg
     9061 ttgaccaaga tcgaacgggg gcatgaggat ttcgacttga tctgtccctc ggagtatatc
     9121 cttgagcgca tgctgcggaa aaatctcttg ctaccgatcg accgtaattt cgggaagaca
     9181 ccggattata tcaacaatgt ctctccctat atccaagcgg aactgaataa attgagtcag
     9241 ccgggccgga agactaccga ctacgtggtt ccttatatgt ggggaaccgc cggcctgttg
     9301 tataataaag ccgatgtctc gagagacgag gtcatgtcgt ggaaatgcct ttgggaccct
     9361 cgtttcagga ataagatctt gatgaaggat agctatcgtg acgcttatgg aaccgccatc
     9421 atctacgccc atgcgaggga attggcggac ggtaccttca cggtggagca attgatgaac
     9481 gatagctccc cggaaatgat cgctatcgcc gaggaatact tgaagaagat gaaaccgaat
     9541 atcgccggtt gggaggccga tttcggtaag gagatgatga cgaaaggaaa ggcgtggctg
     9601 aatttcactt ggagcggcga cgcggtctgg gccatggaag aggcgagtgc cgtaggcgta
     9661 gatctggggt atgaggttcc tttggagggt agtaatatct ggtacgatgg ttgggcgatc
     9721 cctaaatacg ctcgcaacgt gaaggcggcc agttatttta tggactatct atgccgtccg
     9781 gacatcgtca gccgtaatat ggaggtgacc ggatatgtca gcaccgtggc caccccggaa
     9841 atattggcgg aaaagatcga tacgacgcag accgagttct cggacgtaag ttatttcttc
     9901 ggaccgggag cggagcgtgt ccagatagac ccggctcaat atccggaccg gaaggtcgtg
     9961 gaacgttgtg ccatgatccg tgatttcggg aacgagacgg aggtggttct ggaaatgtgg
    10021 agccgggtaa aaggtgacaa tcttaactct tggattgtta tattgatatt cgctgttttc
    10081 ggcttgttgt ttgtctgggt cgtttacaag cggatcaatc gttatcaaca gaaaagacga
    10141 catcgcagac gtcgtagctg gtataaaaag aaatgatatg gaaggcataa agaacttgat
    10201 tatagacttg ggcggtgtgc ttattaacct gactcgcaac cgttgtatcg aggctttcga
    10261 gaatctgggc gtggagaata tccgggaaca gatcacgaat aactatcaac ataaggactt
    10321 gtttgagcga ttagagttgg gaacgatttc ggtggaacag tttcgcgatg atattcgtgc
    10381 cttatcggga aagcccctga cggacgaaca aatcgacacg gcatggatcg ccatgttggg
    10441 agacgtcccg gaaaataagt tgcgtttgct attggagctt cgtgaacgct ataatacgat
    10501 gcttctgagc aatacgaacg agcttcattg gaaatggtcc gaagatacct atttctctta
    10561 tcaaggtctt tgtgcccaag atttcttcca taagatttac ctctcttacg aattgcatat
    10621 gctgaagccg aacgcggata tttttgagta cgtactgaag gactcgaatc ttttagccga
    10681 ggagactatg ctgattgatg acgcttccgt gaattgccgg gcggctgaat tattgggaat
    10741 gaagtcctat atgccgcagc aaagggagga ttggtcgcat ctattcaaat gaaggccggt
    10801 cattgtttgg tcccggccta aatgtcttta acctttagga tattatacga ggtaccaaga
    10861 tcatacacat cattcccgtc tactttcttg atgtacttta cgacacggat ggtgacggga
    10921 aggatgataa cctcgtacaa ggatttaagt accgcctgcg tcccgatcat gataagcaat
    10981 tctccggccg ggatcaatcc ggcgaaggcg atcgggaaaa agatcaggga atcggcgctc
    11041 tcaccgataa gggtagatac gatcgctcgt aacgagaaat tctttccgtt ggaggcgatt
    11101 ttcattttgc tcatcacata ggcgttcagg aaagaaccgg ccaaaaacgc tatcaagctg
    11161 gcgaccgcta tacgtggggc catcccgaag acgaaattga aaccttcctc cccctcccag
    11221 aaaggggcgg ccggtaataa taccgccaat tgcgcgaatg cgatcaccag aaaattagag
    11281 gcgaagccac tccagataat tagccgtgcc ttcttgaatc cccacacttc cgctatacaa
    11341 tcattgatga tatacgagat cgggaatacg atcaaacctg cggtagccgt tatactgcct
    11401 acttgcacta cttttgtctc taaaagattg gacgctacaa ggcatatatt aaaaagtata
    11461 cctagcagca tgaaaggtac tgtaactgtt ttttgcatgt cttcttgttt ttaacgaggt
    11521 ttatcaagca ctcgggacgc aaaggtacga aaattcttat taaaaacgat gggtatagca
    11581 gataccgatc gcatggcggt aattcacggg atcgtctaca ttaaatatat ggtagcgata
    11641 atagagttgg aggttattgt tcgggtttag ttggtaatta cttcctgtgg agaaacggat
    11701 cttatcggac cgcatcttat ttcgcgtatc attgaagacc tcggtgtagg caaaaggaca
    11761 gaaaccactc ttgccgatct tataggagag ggtcagcatc gaacgcagat aattcttggg
    11821 atgttcggcg tgaaccttat aggtactttg aaaacgttcc cggacagaga gggtaaaacg
    11881 tccggccgaa taagtccccg tagcgtagag ataatatcgg tttcgtaact cgtcggatgc
    11941 cttgtatcgt gctagagaca tatatccgct tcctgccaga agatatttat taaacttgta
    12001 gtttacctca acggtggtga ggaaccattc cgcttcctta aagtcatctc tcggacggat
    12061 gtcctcttct acaagaaagg ataaatgctt atagattttt ccgcataggc tcgccttgaa
    12121 atacacacct gcgccttcca ttccgtatag ggatgaagtg catcctatta taaagaatag
    12181 gatcagataa atagatcgtt ttgtatatga tgtgtttttc atgtagagtg acttccgatg
    12241 caaaagtagt gtttttggat gtaataccaa cgcctcagga tattatatcc gatttttctt
    12301 atatttgtct cctattaact atcaaattcg aatacatgga aaacatatca agaagaacgg
    12361 ctatcaagac atttttagct ggaggcgtgg ctttggcgac tacaggtatc gaggcggtag
    12421 ccgccgcgaa aaagaaaaca gacgtgaagg aacccttgaa aggaaatgtc cgccactccg
    12481 taagtaaatg gtgtttcggc gattataagc tggacgagtt ctgtgagatc tgcaagcata
    12541 tagggattga atccgttgag ttgctggacc cggtagattg gccgatcgta caaaaacatg
    12601 gcctgacggt ggcgatggca caaggggccg ggcttggaat agatcgaggt ttcaatgatc
    12661 cggccttgca tgacgagttg gtcgccagtt atgagaaggt gatcccgatg gtggcggacg
    12721 ctggattgac aaacttgatt tgcttctccg gcagacgtaa tggcgtaacg gacttgcaag
    12781 gctgggagaa ctgcgagaag gggttgaagc gccttatccc gttagcggag aaacacaagg
    12841 tcgtcttgac catggagctt ttgaacagtg tcggtcataa ggattatctg tgcgatcata
    12901 cggtttgggg ggcggaactt tgtcgccgta tcggttcccc taattttaag ttactatatg
    12961 atatttatca tatgcagatc atggagggga atatcatcga gaatatccgt aaataccatc
    13021 cttatttctc gcacgtacat accggtggaa gtccgggccg tgccgagatc gacgagacgc
    13081 aggaacttta ttatccggct atcatcaagg ctcttacgga gacaggctat aaaggcttcg
    13141 ttgggcagga gttcgtcccc gcccaagaag acaagatcgc ttccttggag aagtgtatcc
    13201 gtatctgtga tgtatagggc tatttagtaa taacttacag tgccaagcc
//
LOCUS       DBMDTB010000103        13073 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_1445_length_13073_cov_12.257323, whole genome shotgun
            sequence.
ACCESSION   DBMDTB010000103 DBMDTB010000000
VERSION     DBMDTB010000103.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 13073)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 13073)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13073
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1445_length_13073_cov_12.257323"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..1536
                     /locus_tag="ACZPB4_13935"
     CDS             <1..1536
                     /locus_tag="ACZPB4_13935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SusD/RagB family nutrient-binding outer membrane
                     lipoprotein"
                     /protein_id="HIR1099350.1"
                     /translation="CTGKFEEYNTDNTGFTDEQKTYDYNTFGVWLKVVQMGIYFNYDW
                     GSGKNWHFQTMQNLNADMFSGYMHDFKPFNAGLGNTVYNLQDGWNGTMWDNTYGYIMT
                     EIKQTEDHSRDKYPAFYAIAKILKVEVMHRISDYYGPIVYTKFGESDAGVMPDSQKDA
                     YYAFFRDLGEAIHLLSEYDGEETFSRFDMIMPANYRTFGEWMRFANSLRLRLAIRIAM
                     ADPDKARDEAHKSLTHPAGLLEEAYEVVAVSTAGTGYSNPLGEINKAWGEVFMNANME
                     SILKGYKDPRLSRYFEPATGQGYSGEYRGIRQGTGFNHSRYSEHSRSTITQKTDAILM
                     TPAEVWFLRAEAALRGWSGEDAGTCYEQGVRSSFSQWRVGEANAYLRSDHVAADFVDT
                     FTPEYSAKALCLVSPAWDEEASRETKLEKIITQKWIACYPEGCEAWAEQRRTGYPRLF
                     PVLVNKSNGKIDTRTMIRRLNFPVSIISGNPAQYSALCEYLGGPDTGGTRLWWDTGVN
                     FRD"
     gene            1628..2029
                     /gene="nikR"
                     /locus_tag="ACZPB4_13940"
     CDS             1628..2029
                     /gene="nikR"
                     /locus_tag="ACZPB4_13940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016151 - nickel cation binding [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0010045 - response to nickel cation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nickel-responsive transcriptional regulator
                     NikR"
                     /protein_id="HIR1099351.1"
                     /translation="MSLKRFGVSLEDNLLESLDQYVNENGFANRSQAIRFLIEKNVAE
                     RKWQCNHIVAGTIVIMYDQVKKEISLKITGIQQNYKDVILSSSQYYINQNFCLHIVTV
                     MGTAHRLTELSDKLTTIKGIKHGKLVMSRAD"
     gene            2122..3993
                     /locus_tag="ACZPB4_13945"
     CDS             2122..3993
                     /locus_tag="ACZPB4_13945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor plug domain-containing
                     protein"
                     /protein_id="HIR1099352.1"
                     /translation="MRKELLLVSGLLIGSMAFAIDPAEIDSLINLKGVVVSANKIHVN
                     RNSVPLSISVIEREEIEASSESALLPVLSERVPGLFVTEKGITGFGVSEGAAGTVNIR
                     GVGQGNKVLMLFDGQPQWAGIFGHSLPDTYVASDVERVEVIRGPGALLYGSNAMGGVV
                     NIITRQHNQPGRRTQARIMYGSYNTQKYMINNGYNIGNFSSYISLNHDRTDGHRPDSK
                     FHITNGFAKLGYKIDDHYKVTGDVSLAKFKNQNPGEITNPLIDNIMNILRGTTSFALE
                     NNYGKTSGALRAFYNWGHHRIDDGYNPGGTPNPYLFYSDDHNAGFLFYQSFRLVKGNS
                     FTVGIDYKNWGGNAWQDSINGNQNELVNKTVNEVAGYVIMQQDLFDKVSLNAGVRYEH
                     NSIFGGEWIPQAGFTVRPFEGNVIKASLSKGFRSPNIREMYMFPPQNPDLKPERMMNY
                     EVSIGQTFLDGNLFTELTAFFIDGQDMIETTRIDGRPKNVNTGTFTNKGIEFDSRYQI
                     LKNLSLDMNYSYLHTSKALLAAPAHKFFAGVMYAPGRFTFNVNVQSIFDLYINTADKV
                     KEDYTVLNAKAAYRFGTRDKGLNLFVKGENLTATRYSINEGFPMPKAIFMGGIDVTF"
     gene            4125..4520
                     /locus_tag="ACZPB4_13950"
     CDS             4125..4520
                     /locus_tag="ACZPB4_13950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HIR1099353.1"
                     /translation="MDVKNDLGGGKPTLLIAEDEESNYLLLKTILHKYCNLIRAKTGL
                     EALALFKENEVDLILMDIKMPEMTGIESLKEIRKLSKDIPVIMQSAYVFDSDMEAAKE
                     AGASGFITKPINLKVLKNTISQYCSSIVW"
     gene            4644..6758
                     /locus_tag="ACZPB4_13955"
     CDS             4644..6758
                     /locus_tag="ACZPB4_13955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KamA family radical SAM protein"
                     /protein_id="HIR1099354.1"
                     /translation="MIKKEHLVSDISKLKKVYNQSFPWLVTLAEESENAKYFKDALRS
                     LILSRLTEKESTQENVGMAVAMRILLLIEHDDTFVDELSTGERLPVRTVTYLWQFLTG
                     HLENEVSPDLFIDLYHQFDLLEHPVEILPDRALVKRQMNRWPTGLGPEVIAIRERNKE
                     RIIACLIKKIERRHSLSSRFQFAEGISYEEKEARVREWWNTARFHLSMAIKSPTELNF
                     FLGYSLSDETMSLLARAKKKGMPFFVTPYYLSLLNIEHEGYDDATVRSYIMYSNELVD
                     TYGSIKAWEKEDMVVADEPNAAGWLLPEGHNIHRRYPEVAILIPDSMGRACGGLCASC
                     QRMYDFQSERLNFDFEALKPKESWDRKLRRLMRYFEEDAQLRDILITGGDALMSQNAT
                     LRKILEAVYKMAVRKRKANESRSEGEKYAELQRVRLGSRLLAYLPLRVTDELVGILRE
                     FKEKASAIGVSQFYIQTHFQSPLEVTPEARHAIEAILAAGWTITNQLVYTVSASRRGH
                     TAKLRQTLNALGVVCYYTFSVKGFRENYAVYTPNSRSLQEAREEKIFGQVPEEKQAEL
                     YDMIRNQRPLGKCLVRFLKENGLLFAGTDRNVLNLPAIGKSMTFHTIGLTSEGKRILK
                     FDHDGSRRHSPIIDQMGEVYIVENKSVAAYLRQLKEIGEDVNEYRTIWNYCEGETEPR
                     FSIYEYPAYPFKATDRMTNLEL"
     gene            6830..7372
                     /locus_tag="ACZPB4_13960"
     CDS             6830..7372
                     /locus_tag="ACZPB4_13960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin domain-containing protein"
                     /protein_id="HIR1099355.1"
                     /translation="MIQNEREIRHELVLQAARRMMTAARTAPKGKGIDIIEIAMVTDG
                     DILRLSDEMIRIAAETGFKFLLRDAENIKSADAVVIIGTSQKVQGLNCAHCGFDTCVE
                     KPDLVPCAINSVDLGIAIGSACATAADLRVDTRVMFSAGLAAQRLGLLEDCKCVMAIP
                     VSASSKNPFFDRKPKEEPKN"
     gene            7379..8347
                     /locus_tag="ACZPB4_13965"
     CDS             7379..8347
                     /locus_tag="ACZPB4_13965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099356.1"
                     /translation="MSDSILKFANKLEIRYSFNNKSNYMDAMTKHRCEKEILTLIRSL
                     ADMLDVKLTVYNEPYDKEGGFREKLGVAGESSRSISIVLNLVMQILTRPSLSVGGQPL
                     MDRTPADEEEMQRELSKLRRELRLKTPGATPSHRLIDLLNASPRFCKCKSNFYEALKG
                     YPKVTKISVRELNEKDRSRSGSLEVKRDQFDYFILRSDDLPTVKDNKATIEIISPVLK
                     DSKYRWKGIYNKGGETIDFYMQDEDFKKQMFEDKISFTSGMCIDCVLEIVRRLSELGE
                     VVNVSYTVTTVIRTRFDKMEIVTPQGKRHLRKLEAAKKQLTLDLFG"
     gene            complement(8613..8855)
                     /locus_tag="ACZPB4_13970"
     CDS             complement(8613..8855)
                     /locus_tag="ACZPB4_13970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099357.1"
                     /translation="MTTMELRADIFENLNFLLDNEEAMTQLKKYLCQLRNKVERDSPC
                     KYDVGELTQRVRQGVQDARQGLGQSHDDLVKEAETW"
     gene            complement(8912..10207)
                     /locus_tag="ACZPB4_13975"
     CDS             complement(8912..10207)
                     /locus_tag="ACZPB4_13975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC family protein"
                     /protein_id="HIR1099358.1"
                     /translation="MGELERRPNAWALTPLVVFLLTYLVISIVAGDFYKMPITVAFVI
                     SSIVAIAISKGGKLSNRIEQFCRGAANSNIMLMVLIFILAGAFAQTAKAMGAVDATVN
                     LAMSILPGNLLAAGIFLAACFISISVGTSVGTIVALAPVAVGIADKTGMPDALMLGVV
                     VSGAMFGDNLSFISDTTIVATRTQGCQMSDKFKVNIRIALPIAILTGLIYVLVGSGVE
                     NAYAPAPIEWVKVIPYLVVLVTAVCGINVMLVLFIGIVLSGIVGLWTGSFDIWGWNAS
                     MGLGITNMGELIIVTLLAGGMLEMIRYNGGIDWIIRKLTSRIHSSKGAEMSIAALVSF
                     ANLCTANNTIALIMAGPIAKDIADRFKIDPRRSASLLDIFSCFIQGIIPYGAQMLMAA
                     GLGHVSPIEIMQYLYYPYLLGAGALLAIAFNYPRKYTVN"
     gene            complement(10262..12850)
                     /locus_tag="ACZPB4_13980"
     CDS             complement(10262..12850)
                     /locus_tag="ACZPB4_13980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5686 and carboxypeptidase-like regulatory
                     domain-containing protein"
                     /protein_id="HIR1099359.1"
                     /translation="MIRSIRYITLLVLLQFVTGISVLYAQSITSASGIVRDSVSGEPL
                     SYVSVMFENSTIGAMTDDDGAFSLQNDKGLTRLVVSSLGYDNKVVNLKAGQKNDNLDI
                     LLSPTSFQIAEVEVRPTKERYSRKDNPAVELIKKVIEHKNDNRIEAKDEYQSEVYEKL
                     SMSLDDFNPNLEKNKFLKKFKFIKNYLDTSEFNGKPILTISVRETISDQYYRKHPKAE
                     KTITKAKRQQGIDKTLDDGGAITANLEEIFKGVNIFDNNINILLNRFVSPLSSTLAVS
                     YYKYYIMDTVDVAGDKCVDLAFVPVNSQSYGFTGRLYITLDGNYAVKKFLLNTPANIN
                     LNWVDKLRIEQEFKRMPDSTWVLANENTYVNFYIVKGAQQLYAHQLRNFDKYQFDVQN
                     ADSIFGLLGPIHELPEATAQTDTFWIHNRHVPLKEKESALDDLLAQLRKVPAFNVIIK
                     TAEILITGYIPTTADKDKSKFDFGPMNTTFSANHLEGFRMRVGGMTTANLNPHWFGSG
                     YLAYGVNDRKLKYNAKLTYSVNKKKYHEGESPVNNISAIQEYDVYTPGQDFLFTSKDN
                     MFVAWKVGEPVTMMQYIRKTMLQYQKEWLNGLTLTTWARNENNEAAGTLRYDRYNADG
                     TLTNLKSFTNTELGAQLRFAPGERAYNGREGKNSLFNLSKDAPVFKLSHQMGLKNVLG
                     GDFNYNHTEISAEKRIWLSSFGHIDALVTAGKVWDKVPFPLLIMPNTNQSITIQPQAF
                     NMMRALEFVSDQYVSFYFTYYMKGWILNRIPGVKWLRLREVISFSGFYGGLTDKNNPA
                     LDPTGLYRFPEGTSPMGRTPYLEASVGLENIFKILRIDYYRRLTYLDQPNIKKGGVRI
                     ALRFSF"
BASE COUNT         3191 a         2889 c         3525 g         3468 t
ORIGIN      
        1 tgtacgggta aattcgagga gtataatacc gataatacgg gttttaccga tgagcagaaa
       61 acgtatgatt ataatacgtt cggtgtctgg ctaaaggtag tccagatggg gatttatttt
      121 aattatgatt gggggagtgg caagaactgg catttccaga cgatgcaaaa tctgaacgcg
      181 gatatgtttt ccggttatat gcatgatttt aaacccttca acgccggatt gggaaatacg
      241 gtctataatt tgcaggatgg ctggaatggc acgatgtggg ataatacgta tggatatatc
      301 atgacggaga taaagcagac ggaagatcat tcccgtgata aatatccggc tttctatgcg
      361 atcgctaaaa tactgaaagt agaggtcatg catcggatct cggattatta tggcccgatc
      421 gtgtatacga agttcgggga gtcggatgcc ggggtaatgc cggattccca gaaagacgct
      481 tattatgctt ttttccggga tttgggggag gctattcacc tgctgtctga atatgatgga
      541 gaggaaacct tttctcgttt cgatatgatt atgccggcga attacaggac gtttggggaa
      601 tggatgcgtt tcgccaactc attacgtttg cgcttggcga ttcgtatcgc tatggccgac
      661 cctgataagg cgagggatga ggcgcataag tcgctgacac atccagccgg tttgttggag
      721 gaggcttatg aggtcgtcgc agtttctacc gccggaaccg gctactcgaa tccgctaggg
      781 gagatcaata aggcgtgggg agaggttttt atgaacgcta atatggaatc gatccttaag
      841 ggatataaag accctcggtt atctcgttat tttgagcctg ctaccggaca gggatattcc
      901 ggggagtacc ggggaatccg gcaagggaca ggatttaatc attcccgcta tagtgagcat
      961 tcgagaagca cgattaccca gaaaacggac gctatcttaa tgacgcccgc ggaagtttgg
     1021 ttcttacgtg cggaggcagc cttgcggggc tggtccgggg aggacgccgg gacttgctat
     1081 gagcaaggcg tacgatcatc gttcagccaa tggagggtag gagaggccaa tgcttatttg
     1141 cggagtgatc atgtagccgc cgatttcgtg gatacgttta ctcccgagta ttcggcgaag
     1201 gcgctttgct tggtgtctcc ggcatgggat gaagaagcct ctagggagac caagctggag
     1261 aagattatta cccaaaaatg gatcgcttgt taccccgagg gctgtgaggc ttgggcggag
     1321 cagaggcgta ccggttatcc tcgtttgttc ccggttttgg tgaataaaag caatggaaag
     1381 atcgatacgc gaacgatgat tcgtcgcttg aatttcccgg ttagcattat ttccggtaac
     1441 ccggctcagt attccgcctt gtgtgagtat ctgggaggtc cggataccgg aggtactcgt
     1501 ttatggtggg ataccggagt gaattttcgt gattaacgac taatttttcc tcttcctgcc
     1561 aatataatac cgagattccc ctaaaaaata ctacctttga catcgaaaat tataaaaaaa
     1621 gggttttatg tctttaaaac gttttggtgt ctctttggaa gacaatctgt tggaatcatt
     1681 ggatcaatat gtgaatgaga atggtttcgc caatcgttcg caggcgattc gttttctgat
     1741 agagaagaat gtagccgaac gtaaatggca atgcaaccat atcgtagccg ggacgatcgt
     1801 gatcatgtat gaccaagtca agaaagagat ctcattgaaa atcacgggta tccaacaaaa
     1861 ttataaggat gtgattttgt cgtcttccca gtattatatc aatcagaatt tttgcttgca
     1921 tatagtgacg gtgatgggaa cggctcaccg cttgacagaa ttgtcggata agttgacgac
     1981 aatcaaaggc attaagcatg gtaagttggt gatgagccgg gcggattaat gctttttttt
     2041 gcgggcttgg taacacgttt tttggtaaac gtgccactac gggatgttta aaatgataaa
     2101 tattatagat gtaagtagta tatgagaaaa gaacttttac tagtttccgg actgttgata
     2161 ggctccatgg cgtttgcgat agatccggca gagattgaca gtctgatcaa tttgaaaggg
     2221 gtggtggttt ccgccaacaa gatccatgtg aaccggaaca gtgtgccatt atctatctcg
     2281 gtcatcgaac gggaggagat tgaggctagc agtgaatcgg cgttgcttcc cgtattgtcg
     2341 gagcgagtac ccgggctgtt tgtcacggaa aaagggatta caggtttcgg cgtttccgag
     2401 ggagcggccg ggacggttaa tatccggggt gtcggacagg gtaataaggt cttgatgttg
     2461 ttcgacggac agcctcaatg ggccggtata ttcggccatt cgcttccgga tacctatgtg
     2521 gcttcggacg tggaaagggt ggaggtgatc cgtggtccgg gtgccttatt atacggttcg
     2581 aacgctatgg gaggtgtcgt gaatatcatt acccgccagc ataatcagcc gggacgacgt
     2641 acacaagccc gtatcatgta cggctcgtat aacacccaga agtatatgat taataatggg
     2701 tacaatatcg gtaactttag tagttatatc tcattgaatc atgaccgcac ggatggacat
     2761 cgtccggatt cgaagtttca tatcacgaat ggtttcgcta agttaggata taagattgat
     2821 gatcattata aggtgacggg agacgtaagc ttagctaagt tcaagaacca gaacccggga
     2881 gagataacaa atccgcttat cgataatata atgaatatcc tgcgaggtac tacctccttc
     2941 gctttagaaa ataattacgg gaagacaagt ggtgcccttc gtgctttcta caactggggc
     3001 catcatagga ttgatgatgg gtataatccg ggcgggacgc ctaatcctta tctgttttat
     3061 tcggacgatc ataacgccgg tttcttgttt tatcagtctt tccgcttggt gaaagggaat
     3121 agttttacgg tcggtatcga ttacaagaac tggggtggta acgcatggca ggatagtatc
     3181 aatggcaacc agaatgagtt ggtgaataag accgtaaacg aggtagccgg atacgttatc
     3241 atgcagcagg atctatttga caaggtaagt ttgaacgccg gggttcgtta tgagcataac
     3301 agtatcttcg gcggcgagtg gattccgcag gccggcttca cggtacgtcc gttcgaggga
     3361 aacgtgataa aggcttcttt gtcgaaaggc ttccggagtc cgaatatacg ggagatgtac
     3421 atgttcccgc ctcagaaccc agatttgaaa ccggagcgca tgatgaacta cgaggtatcc
     3481 atcggacaga cattcttgga tggcaacttg tttacggagt tgaccgcctt ttttatcgac
     3541 gggcaagata tgatcgagac gacacgtata gacggacgcc ctaagaatgt caatacgggt
     3601 acttttacca ataaaggtat cgagttcgat tcccgctacc agattctcaa gaatttaagc
     3661 ctcgatatga actatagcta tttgcatacg agcaaggccc tgctggcggc tccggcgcat
     3721 aagtttttcg ctggcgtgat gtatgccccg ggacgtttca ctttcaacgt gaacgtacaa
     3781 tccattttcg acctttatat caatacggcg gacaaggtga aagaggatta cacggttctg
     3841 aatgcgaagg cagcctaccg tttcggtaca cgtgataaag gcttgaatct atttgtcaaa
     3901 ggagagaatt taacggctac ccgttattcc atcaacgaag gattcccgat gccgaaggcg
     3961 atattcatgg gaggtataga tgttactttc tagcgtgggt agaaaaagaa cttcctcgaa
     4021 tactcatatc tccttgaatt ttatgtctac tttctaatat ttgttttatc tttgcttcat
     4081 cagagtttat ttgattttga ttaaaagaat aaaacgttat atatatggat gtgaaaaatg
     4141 atttgggtgg aggaaagccc acgttgctaa tcgcggagga tgaggaaagt aattatttac
     4201 ttctgaagac cattttacat aaatattgta atttgatccg tgctaaaact ggtttggaag
     4261 ctttggctct ctttaaggaa aacgaggtgg acttgatctt gatggatata aaaatgcctg
     4321 agatgacggg tattgagtcc ttgaaagaaa tccgtaagct atcgaaagat atccccgtaa
     4381 tcatgcagtc agcttatgta ttcgactctg atatggaagc cgctaaagaa gccggggctt
     4441 ccggttttat cacgaagccg atcaatctaa aggtattgaa aaatacgata tcgcagtatt
     4501 gttcgtcaat cgtatggtaa ggatttatta agatgtttta gatttgtata aacggcattt
     4561 tgccgtattt tttgttattt ttgtagaaaa tcgtcaagag gacgctttac aaatgtattc
     4621 taatctacaa aaatggcatg cttatgataa aaaaagaaca tcttgtatcc gacatttcta
     4681 aactgaaaaa agtatataac cagagcttcc cttggttggt gaccttagcg gaagaaagcg
     4741 agaacgcaaa gtattttaag gatgctttgc gttctcttat tttatcccgg ctcacggaaa
     4801 aggaaagtac ccaagaaaac gtaggaatgg cggtggcgat gcgtatcctt cttttgattg
     4861 agcatgatga tactttcgtg gacgagctgt ctacgggcga gcgtcttccg gtgcggacgg
     4921 tcacttatct ttggcagttc ctgaccggcc atttggaaaa tgaggtctct cctgatttat
     4981 ttatcgacct ataccatcag tttgatttat tggaacatcc ggttgagatc ctgccggacc
     5041 gggcattggt gaaaaggcag atgaaccgtt ggccgaccgg actcggcccg gaggtgatcg
     5101 ctatccgtga gaggaacaag gagcgtatca tcgcttgctt gatcaagaag atagaaagac
     5161 gccatagcct ttcgtcacgt tttcagttcg ccgagggcat ctcctatgag gagaaagagg
     5221 ctcgggtacg tgagtggtgg aatactgctc gtttccattt gtcgatggcg atcaagagtc
     5281 ctacggaatt gaacttcttt ttgggatatt ccctgtcgga tgagacgatg agcttattgg
     5341 cccgtgccaa aaagaagggg atgccctttt ttgtgactcc ttattatctt tccctattaa
     5401 atatagaaca tgaggggtat gatgacgcta cggtgcgatc gtacatcatg tactcgaacg
     5461 agctggtaga tacgtatgga agcattaagg cgtgggaaaa ggaagacatg gtcgtcgccg
     5521 atgagccgaa tgcggcgggc tggctattgc cggagggaca taatatacac cggaggtatc
     5581 cggaggtggc gatcttgatc cccgattcga tggggcgtgc ttgcggtgga ttgtgcgctt
     5641 cttgccagcg catgtatgat ttccagagcg agcggttgaa tttcgatttc gaggccctga
     5701 agcctaagga gagttgggac cggaagttac gtcgtctgat gcgttatttc gaggaagacg
     5761 cccagctacg ggatatcctg ataacgggcg gggatgcctt gatgagccag aacgctacct
     5821 tgcgtaagat attggaggcg gtatataaga tggcggtgcg gaaacggaag gcgaacgaga
     5881 gccgttcgga gggcgagaag tacgccgagc tgcaacgggt acggctaggt tcccggttgc
     5941 tggcttatct tccgctgcgt gtgaccgacg agttggtcgg tatattgagg gagttcaagg
     6001 agaaggcttc cgctatcggt gtgagccagt tctatataca aacgcatttc cagtctccac
     6061 tggaggtgac accggaggcg aggcacgcta tcgaggcgat cttggcggcg ggctggacga
     6121 tcacgaatca gttggtttat acggtctcgg cttcccgtag ggggcatacg gcgaaattac
     6181 ggcagacctt aaacgccctt ggggtggttt gctattatac gttctccgtg aagggattcc
     6241 gggagaatta tgcggtttat accccgaata gccgctcgtt gcaagaggct cgtgaggaga
     6301 agatcttcgg gcaggtgccg gaggagaaac aggcggagtt gtatgatatg atccgtaacc
     6361 agcgtccttt aggcaagtgc ttggttcgtt tcctgaagga gaacgggttg ctgttcgccg
     6421 ggacggatcg taacgtgttg aacttgcccg ctattggtaa gagcatgact ttccatacca
     6481 ttggactgac ttccgaggga aagcggattc ttaagttcga tcacgacggg agccgtcggc
     6541 atagcccgat tatcgatcaa atgggtgagg tctatatcgt ggagaataaa tccgtggccg
     6601 cttaccttag gcaattgaag gagataggcg aggatgtcaa tgagtaccgt acgatctgga
     6661 attattgcga gggagagacc gagcctcgtt tcagtattta tgaatacccg gcttatccct
     6721 ttaaggccac ggaccgaatg actaatcttg aattatgaat tctatcctca tgtgtttgcc
     6781 ttggtttcgt atattttgct taattttgtt tcattgaatt tagaaggata tgatacagaa
     6841 cgaaagagaa atcaggcatg agcttgtgtt acaggccgca cgccgcatga tgacagccgc
     6901 tcgcacggct cctaaaggca agggtattga tatcatagag atagcgatgg tgacggatgg
     6961 ggatatcttg cgcctgtccg atgagatgat ccggatagcg gccgagaccg gattcaagtt
     7021 cctgcttcgt gacgccgaga atataaagag tgccgacgcc gtggtgatta tcggtacctc
     7081 ccagaaagta caaggcttga actgcgccca ttgcggtttc gatacctgcg tggagaagcc
     7141 ggatttggtt ccgtgcgcta ttaattccgt cgatctgggt atcgcaatcg gctcggcttg
     7201 cgctacggcg gcggacttgc gtgtggatac ccgtgtcatg ttcagcgccg gcttggcggc
     7261 ccagcgattg gggctgttgg aagactgtaa atgcgtgatg gcgataccgg tcagcgcctc
     7321 gtcgaagaac ccgttttttg atcgtaaacc gaaagaagaa ccgaaaaact agaaacaaat
     7381 gagtgactct attctaaaat ttgcgaataa gctggagata cgttattcct ttaataataa
     7441 atccaattat atggatgcca tgaccaagca ccggtgtgag aaggagattc ttacgctgat
     7501 acgttccttg gcggatatgc tggacgtgaa gctgacggtt tacaacgagc cttacgataa
     7561 ggagggtggt ttccgtgaga agctgggcgt ggccggggag agtagccgct ctatctctat
     7621 cgtgttgaac ttggtgatgc agatattgac ccgtccctcc ttgtcggtgg gtggacaacc
     7681 gctgatggac cgtacgccgg cggacgagga ggagatgcag cgtgagctgt ccaagttacg
     7741 ccgtgaacta cgactgaaga ctccgggggc tacgccttca caccgcttga tcgacctgtt
     7801 gaacgcctcg ccccgtttct gtaagtgtaa gtctaatttc tacgaggctt tgaaagggta
     7861 tccgaaggtg acgaaaatct cggtacgtga gttgaacgag aaggatcgta gccgttccgg
     7921 ttcgctggag gtgaagcggg accagttcga ttattttatc ttgcgtagcg acgatctgcc
     7981 tactgtcaag gataataagg ccacgataga gatcatctcg ccggtactga aagacagtaa
     8041 atatcgctgg aaaggtattt acaacaaggg aggcgagacg atcgatttct atatgcaaga
     8101 tgaggatttt aagaaacaga tgttcgagga taagatctcg ttcacgagcg gcatgtgcat
     8161 cgattgcgtc ttggagatcg tccgccgtct gtcggagcta ggagaggtgg tcaacgtgag
     8221 ctataccgtg actacggtga tacgtacccg tttcgataag atggagatcg tcacccctca
     8281 aggcaagcgg catcttcgta aactggaagc cgcgaagaag cagcttacgc tggatttgtt
     8341 cggctaatcc gattgccgta ttcccatcgc tcccaagcac tacagtgttt ctacttgaac
     8401 acagtaatat tcatcagcga acacaatagt attcaatccc ggacacaata gtctttttgc
     8461 tttgaatact attgtgtttt cacatagagg atctgtacgt cttatttatt cttctccaag
     8521 cttatcttgt aatagtttgg gattattacg gcaatcccaa accgcaacga tatgacaggt
     8581 atctttctcg tggaagtaaa ttaattttat ttttaccatg tttcggcttc ttttactagg
     8641 tcgtcgtgac tttgtcctag gccttggcgg gcatcttgta caccttggcg tacacgttgt
     8701 gtcaattcgc caacgtcata tttacaaggg ctgtcccgtt cgactttatt tcgcagctgg
     8761 cacagatatt ttttcagctg tgtcatcgcc tcttcgttat ctagcaggaa attaagattc
     8821 tcgaagatgt ctgcccttaa ttccatcgtt gtcatacgga tcctccttat tctttaaatg
     8881 agtactgtga gcaaagataa tgtttatcca tttaatttac cgtatatttc ctcggataat
     8941 tgaatgcgat cgccaataag gcgcctgctc ccaatagata tgggtagtaa agatattgca
     9001 tgatctcgat aggggagaca tgcccgagtc cggcggccat caacatctgg gcgccgtagg
     9061 ggatgattcc ctgtatgaag caagagaaga tatccaatag gctggcgctg cggcggggat
     9121 ctatcttgaa ccggtccgct atatccttgg cgatcgggcc ggccatgatg agggcgatcg
     9181 tattgttggc cgtgcaaagg ttggcgaagc tcaccaaggc cgctatgctc atctcggccc
     9241 ccttggagga atggatgcgg gaggtaagct tgcggatgat ccagtcgata cccccgttat
     9301 agcggatcat ctccaacatg cctcctgcca gaagcgtcac gataatcagc tcgcccatat
     9361 tggtgatacc taatcccatg gaggcgttcc agccccagat atcgaagcta ccggtccaca
     9421 aacctactat accggacagg acgatcccga tgaatagcac cagcatgaca ttgatcccgc
     9481 aaacggcggt taccaacacc accagataag ggatcacctt gacccattcg atcggggccg
     9541 gggcgtaagc gttctccacg ccgcttccca ccagcacgta tatcaatccg gtcaggatcg
     9601 ctatcgggag ggcgatacgg atattcacct tgaacttatc ggacatctgg caaccctgcg
     9661 tgcgggtagc tacgatggtc gtatcggata tgaacgacag gttatcgccg aacatggcgc
     9721 cgctcaccac gacacctagc ataagggcgt ccggcatccc cgtcttgtcc gctataccga
     9781 cggctaccgg ggccaaggcc acgatcgtgc ccaccgacgt acctaccgag atggatatga
     9841 aacaagcggc caagaagatt ccggccgcca acaggttacc gggcaggatg gacatcgcca
     9901 gattcacggt agcgtctacg gcacccatcg ccttggcggt ctgcgcgaac gccccggcga
     9961 ggatgaagat caataccatc agcatgatat tgctattggc cgccccccgg cagaactgct
    10021 cgatacggtt gcttaatttg cctcccttgg agatcgctat cgctacgatc gaggagatga
    10081 cgaaggctac cgttatcggc atcttataga aatctcccgc cacgatagat atcaccaaat
    10141 aagtcaataa gaataccacc agcggcgtca atgcccatgc gttcggtctg cgttccaact
    10201 cccccatttt cttatctctc ctacatttaa ctgtcaactg tcaattctca actgtcaact
    10261 cttagaagga gaaccgcagc gctatacgca cgcccccctt cttgatattc ggttggtcca
    10321 gatacgtcaa ccggcggtaa taatcgatcc gtaatatctt gaagatgttc tccagaccta
    10381 cgctggcctc caggtaaggt gtacggccca tcggcgaggt tccctcgggg aagcggtata
    10441 gtcccgtcgg gtccaaggcc gggttattct tatcggtcag tcctccgtag aaaccgctga
    10501 acgatatcac ctcacgcaaa cgtagccact tcacgccggg aatacggttt aagatccatc
    10561 ccttcatata atacgtgaag tagaacgaaa catactggtc gcttacgaac tccagcgcac
    10621 gcatcatgtt gaaggcttgc ggctggatcg tgatggactg gttggtattc ggcatgatga
    10681 gcaaggggaa agggaccttg tcccatacct tgcccgctgt caccaaggcg tcgatatgtc
    10741 cgaaggaaga gagccagatc cgtttctcgg cgctgatctc cgtatggttg tagttgaagt
    10801 cgccccccaa cacgttcttc aatcccatct gatgggatag cttgaatacg ggagcgtctt
    10861 ttgagaggtt gaaaagagag ttcttaccct ctcgtccgtt ataggcacgc tcgcccgggg
    10921 cgaaacgaag ctgggcccct agctccgtgt tggtgaaact ctttaagttc gtcaatgtcc
    10981 cgtcggcgtt gtaacggtcg tagcggagcg ttccggccgc ctcgttgttc tcgttacgtg
    11041 cccaagtggt aagggtcagg ccattcagcc attccttctg gtactggagc atggtcttgc
    11101 ggatgtattg catcatggtg acgggctcgc ccaccttcca tgccacgaac atattatcct
    11161 tgctggtgaa gaggaagtct tgaccgggcg tatatacgtc gtactcttgg atagcggaga
    11221 tattgttcac cgggctttct ccctcgtgat atttcttctt gttcacgcta tacgtcagct
    11281 tggcgttata ctttagctta cggtcgttta cgccataggc tagataaccg ctaccgaacc
    11341 agtgcgggtt gaggtttgcc gtcgtcatac ctcccacacg catgcggaag ccctccagat
    11401 ggttggcgct gaaagtggta ttcatcggtc cgaaatcgaa cttgctctta tccttgtccg
    11461 ccgtggtcgg gatataaccg gtgatcaata tctcggcggt cttgatgatc acgttgaaag
    11521 ccggtacctt gcggagttgc gccagcaagt cgtccaaggc gctctctttc tctttcaagg
    11581 ggacatggcg gttgtgtatc cagaaggtgt cggtctgggc ggtggcttcg ggcagctcat
    11641 ggatcggacc gagaaggccg aagatcgagt cggcgttctg cacgtcgaac tgatacttat
    11701 cgaaattcct tagctggtgg gcatagagct gttgcgcccc ttttacgata tagaaattaa
    11761 cgtaggtatt ctcgttggcg agcacccaag tactatccgg catccgcttg aactcttgtt
    11821 cgatccggag cttgtccacc cagttgaggt tgatgttcgc cggggtgttc aagaggaatt
    11881 tcttgacggc gtaattaccg tccagcgtga tgtacaagcg gcccgtgaag ccgtagctct
    11941 ggctgtttac gggcacgaag gcgagatcca cacatttatc tccggctacg tccaccgtat
    12001 ccatgatata atatttgtaa taggagacgg ccagcgtgga agataacggg ctcacgaaac
    12061 ggttcaacaa gatattgata ttgttgtcga agatattgac gcccttgaat atctcctcaa
    12121 ggttggcggt gatggcgcct ccatcgtcca aggtcttgtc gataccctgc tggcgcttgg
    12181 ccttggtgat cgtcttctcc gccttgggat gtttgcggta gtattggtcg gagatcgtct
    12241 cacggacgga gatcgtcagg atcggtttcc cgttgaactc cgaggtatcc agatagttct
    12301 tgatgaactt gaatttcttc aggaacttat tcttctcgag attggggttg aagtcgtcca
    12361 gcgacatgct gagcttctcg tacacctcgc tttggtactc gtccttcgcc tcgatgcggt
    12421 tgtcgttctt atgctctatg actttcttga tcagttccac ggcggggttg tccttgcggg
    12481 agtatctctc cttggtaggc ctcacctcta cctccgcgat ctggaaggag gtggggctta
    12541 ataatatatc cagattgtcg ttcttttgcc cggcctttag gtttacgacc ttattgtcat
    12601 atccaagcga ggatacgacc agccgggtaa gccctttgtc attctggagg ctgaaagccc
    12661 cgtcatcgtc ggtcatcgcc ccgatcgtcg agttctcgaa catgacggat acgtaggata
    12721 ggggttcccc gcttacggag tctctcacga ttccggacgc ggaagttatg ctctgggcgt
    12781 ataggacgga aatgccggtc acgaattgta acaggactag caaagtgata tagcgaatag
    12841 atcttatcat gtaaatgtct cgttattcct tcacggataa tacagttggc aaaggtatgt
    12901 ttttttcgtg ggagggaggg gggagaggct attaataatc attaatcaat ggggcatccc
    12961 ctccttggcg ggaggggagc cccatcattc ttaaatctaa aaaacatgag ggcctcacgg
    13021 ctttatatct ctgacggcga ttcgctatcc gcttgcttct tggcggcggc ggc
//
LOCUS       DBMDTB010000104        12835 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_1498_length_12835_cov_10.942516, whole genome shotgun
            sequence.
ACCESSION   DBMDTB010000104 DBMDTB010000000
VERSION     DBMDTB010000104.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 12835)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 12835)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12835
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1498_length_12835_cov_10.942516"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..557)
                     /gene="pgl"
                     /locus_tag="ACZPB4_13985"
     CDS             complement(<1..557)
                     /gene="pgl"
                     /locus_tag="ACZPB4_13985"
                     /EC_number="3.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017057 - 6-phosphogluconolactonase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconolactonase"
                     /protein_id="HIR1099360.1"
                     /translation="MEIKRYNEMKEALRSMTEDMMAMIRRKDFAPFNLALSGGETAKH
                     MFSLWVDEYKDKIDWNNIRFFWVDERCVPPTSPDSNYGHANRLLFTPLRIQADHIHRI
                     KGENEPGTEAMRYSWVVKEFLPLFNQMPTFDCIILGVGEDSHTASIFPTTMELLSDSR
                     NYAVSQQPSTGQYRITMTGPLILNGA"
     gene            complement(562..2028)
                     /gene="zwf"
                     /locus_tag="ACZPB4_13990"
     CDS             complement(562..2028)
                     /gene="zwf"
                     /locus_tag="ACZPB4_13990"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004345 - glucose-6-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HIR1099361.1"
                     /translation="MKKADNQLLVIFGASGDLTSRKLLPSLFELYVRGLLPDRFCILG
                     AARTAYGDEEFRAEQHTHILEAQKGKTYDEGLIDDFLENVYYLAFDSMNADEYYKLRE
                     RIEFLQEKHDLPDKIIYYLATPPVMYEIVPQCLLESGLNKTESPDGFRRIIVEKPFGT
                     SLESARQLNDHLRHIFHEEEIYRIDHYLGKETVQNILVLRFSNGIFEPLWNHNYIDSI
                     EISATETLGVENRGKYYDGAGAMRDMIQNHLMQLMSFIAMESPSIFEPEPIRDEIVKV
                     FRSIRPYTVLDMDKMVVRGQYIGYREEKNVASDSNTETYVAMKFFIDNWRWSGVPFYF
                     YTGKKLPEKSSEVVIHFKSTPHQLFVGQCSGGSCNKLTIRIQPNESISLKFGLKMPGA
                     GFEVKQVSMDFRYDSLSKSYLPDAYERLLLDAMLGDSTLYARSDALEASWKFIDPILL
                     HWKEEGSKNLFFYEPGEDGPEETVILGAEKKVCACQRR"
     gene            complement(2033..3493)
                     /gene="gnd"
                     /locus_tag="ACZPB4_13995"
     CDS             complement(2033..3493)
                     /gene="gnd"
                     /locus_tag="ACZPB4_13995"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004616 - phosphogluconate dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating NADP(+)-dependent
                     phosphogluconate dehydrogenase"
                     /protein_id="HIR1099362.1"
                     /translation="MKTSNIGLIGLAVMGENLALNMESKGFTVSVYNRTAPGEEGVVD
                     RFMSGRGKGKNFIGTHTIQEFVESIERPRKIMLMVKAGAPVDELMAQLIPYLSPGDVI
                     IDGGNSDFHDTERRVKEMEAHGMYFVGTGISGGEIGALYGPSVMPGGSPAAWPLVKDV
                     LQSIAAKLEDGTPCCQWIGPGGAGHFVKMVHNGIEYGDMQLISEAYSLLKNRLDLDNE
                     ALARIFEDWNTGELDSYLIGITADILRFKDEAGEGYLLDKILDAAGQKGTGKWSAIAA
                     MDENDPLTLITEAVYARMLSSMQEERKKASSLYPKSGVLGQTLISEKEIKQALYAAKL
                     VSYAQGFSLLCQASKRYDWQLDYGTIAKIWRKGCIIRSVFLEKITQAYEKNRNLENLL
                     FDEFFIQKIESSLLAWRQVVAEGALHGVALPAMSSGLSYFDGLSTPHSAANLIQAQRD
                     YFGAHTYERVDWERGKFFHTNWTGEGGKTVSGTYNV"
     gene            complement(3504..4883)
                     /locus_tag="ACZPB4_14000"
     CDS             complement(3504..4883)
                     /locus_tag="ACZPB4_14000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HIR1099363.1"
                     /translation="MKKYDAIIIGFGKGGKTLAADLANHGWNVAVVERSTGMYGGTCI
                     NIGCIPTKALVHYAQVTGYRRPSTFEQYAEEFKHAILAKEKLTSLLREKNFKNLDDRE
                     TVTVYTGEASFRSPYEIVVKTDTDSFLLEGEKIFINTGATTIIPTISGIEDNPYVYTS
                     TSIMELEKLPRHLVIVGGGYIGLEFASMFAGFGSKVTILEAGEVFIPREDRDIADSVK
                     STLEKKGITIHLNTVVQTIEQDAERATVICRNAISGDTLRLDAEAVLLATGRKPNTES
                     LNLQAAGIQTTNRGAIEVDSKLRTNIPNIWAIGDVHGGLQFTYLSLDDYRIIREELFG
                     NGFRSLDDREAVAYSVFIDPPLAHVGLNETQARKMEKNIKVASLPAAAMPRTRTIEQT
                     DGLLKAVVDADTGKILGCTLFCAESSEVINTVSLAMRLGQDYTFLRDSIFTHPSMSEA
                     LNDLFGLIK"
     gene            5089..6954
                     /locus_tag="ACZPB4_14005"
     CDS             5089..6954
                     /locus_tag="ACZPB4_14005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005675668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HIR1099364.1"
                     /translation="MITTLIILALSAVFFVNGKLRSDLVALCALVLLIVFNILTPEEA
                     LSGFSNPIVIMMVGLFVVGGAIFKTGLAKMISSKILRLAGKSELKLFILIMMVTAFIG
                     AFVSNTGTVALMLPIVVSMAASANISPGRFLMPLAFASSMGGMATLIGTPPNLVVDEV
                     LSNAGFTDLSFFSFTPIGVICVLIGLVVLIPLSKFFLVKKEDGKDTKTTTGHSPKELA
                     KKYQLSDNLYRIQIRPGSRIGGKKLQELNITQAYNLSILEIRRQSSSQGRFLKTVDQS
                     LAGPHTELQENDILYVFGPFEKVNQFAKEQNLELTDTHVSEYVEGAEVEKLSVREIGI
                     AEVLLMPDSKLINKAVKDSGFRDKYSVNILGIQRKGEYILNDIKDIKMHAGDILLIQG
                     TWDSIARMSQKQSQWVVLGQPLEEASKVTLDYKAPVAALIMVLMIAAMVFDFIPIPPV
                     AAVIIAGILMVLTGCFRNVEEAYKTINWESVVLIAAMLPMSLALEKTGASNLISEKLV
                     SGLGDYGPLVLMAGIYFTTSLLTMFISNTATAVLVAPIALQSAIAINVSPYPFLLAVT
                     VGASMCFASPFSTPPNALVMSAGKYTFMDYVKVGLPLQIVMGIVMVFILPLLFPF"
     gene            7015..7932
                     /locus_tag="ACZPB4_14010"
     CDS             7015..7932
                     /locus_tag="ACZPB4_14010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2156 domain-containing protein"
                     /protein_id="HIR1099365.1"
                     /translation="MDIPFKPIRLEDKEIITSFTFPSDYRNCDFSFANMCSWRFLYDS
                     EFAIVDGYLLIRFMIEDKSRFAYMMPVGDGDLAGAVRLLEEDSLKYGHPLCMLGITPD
                     AKEQLEGALPGSFFYIPERDYFDYIYLREDLATLRGKKYQSKRNHINNFKKQYSYEYV
                     PITPDIVPQCLKLECKWYKANNGDNDEEELNDERRSLTYALHHFDSLGLIGGALRVDN
                     EIIAFSFGAPINHNTFGVHVEKADVNFDGAYTVINQEFASHLPEQYTYVNREEDLGIP
                     GLRQAKLSYQPTILLEKSAAIKKQLTQTK"
     gene            7936..8898
                     /locus_tag="ACZPB4_14015"
     CDS             7936..8898
                     /locus_tag="ACZPB4_14015"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIR1099366.1"
                     /translation="MDKKQQIVNLWRTCFGDSEAFISLYFDRVYKDENAMTIEKDGKI
                     VSALQIVPHTMTYLGTEISVGYISGACTTPEERGQGLMRQLLQETFEEMERREIAISA
                     LIPADPWLFDYYREQGYTEAFDYSVETYIRPNTPVQLPKITVIQPEVPTTDELFAYFN
                     RKLRERPSCILHSQDDFITILRDLQLDNGGMYTALDENEKVVGMAFALPLEAGTAPSD
                     KKLFIKELLYDSEEIKELLLQELTLQNNISQATVNTPPTPPGTLPMGMARIIDTKRMI
                     HLWLSKQHESPVSKKDLEQMDNQTLTRQLMGYQGRMAYMSLMLD"
     gene            complement(9005..11152)
                     /locus_tag="ACZPB4_14020"
     CDS             complement(9005..11152)
                     /locus_tag="ACZPB4_14020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LruC domain-containing protein"
                     /protein_id="HIR1099367.1"
                     /translation="MKRCIFTKVKFMALFLFAVLMTACTADVYEPKPDPDPKPRPDES
                     TNGIPNDFDYSTKASHKLTVKVLDEYEGKRYYTIEVFGSDPITDPNSVFYVGGKTNSR
                     NPFIVDLALPKTQEYIYIKKTDAQGYSTVVSLEVKDGDLLLDYTDPVITKSFLRSDSG
                     ISDQEITRWLTPLSEKEIEKLDKKAEMKDVIELRSGMTLDKNKSYKITSGKVNNVVFP
                     DNENYTLYIFSGATLDLASSASPLTKNSQIVVFHGGQIIGSKAVLKIDGNSQLVNMGK
                     VDINRIETLPSPHSSIYNHTNSEITVNSMHLNGGELHNHCLVKVGTFSFDGSASGLYL
                     NRGSSVISGNFIYGYDTKISMAEHSLFETDALNPAQTGPVSLVVEDADANQYGDGNSA
                     KLFKVNGVLDYTSVQITGFFWSDLYTYAQSEVNYSANKNGALRVVGNKCPVNISGDCF
                     GDINYSKDEPFTDESETPEYKPEYDKTEAYVYLFEDNWPNFGDYDMNDLVMIVSIMNT
                     TEASSEGINAKTVYLSTSVRAVGATKSLYAFAKIQGTDKVINLLEGKEAHEFMNSEPG
                     QIINTYNKTCEARESLIEVDVNGMSGVVNANNLNVFIVWGDPNKNKKNEVHIVGFLGT
                     EQAATALTSDEYYRYKYNENIDNSTEEFNNMMWGLMIPKSSFDSYPREGISIMDAYPQ
                     FMNWAKSGGKDVLDWYTLGVNDLLYQGDSAKDK"
     gene            complement(12050..>12835)
                     /locus_tag="ACZPB4_14025"
     CDS             complement(12050..>12835)
                     /locus_tag="ACZPB4_14025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HIR1099368.1"
                     /translation="HEQSNRSKAPFVAVDCGAIPKELAASEFFGHVKGSFTGAIENKT
                     GAFVAAQGGTIFLDEIGNLTYEVQVQLLRALQERKVKPIGSNQEIAINVRLISATNEN
                     LRQAIEKGDFREDLYHRINEFTIRIPDLKERKEDLLLFANHFLDLANSELRKDIIGFD
                     NDTMQLFQSYSWPGNLRQMKNVIKYATLLATGRYITRKELPEELTENLSSHTNIQLKN
                     VEHERDLIRKALQECGNNKTRAAQLLGIDRKTLYNKLKIYQLD"
BASE COUNT         3538 a         3228 c         2619 g         3450 t
ORIGIN      
        1 gcgccgttca agataagcgg tcccgtcatg gtgatccggt attggccggt agaaggttgc
       61 tgggataccg catagttacg gctatccgac aatagctcca tggtggtagg gaaaatggat
      121 gccgtatggg aatcctcacc tacgccgagg atgatgcaat cgaacgtagg catttggttg
      181 aacaacggca agaattcctt tacgacccat gaataacgca tcgcctcggt acccggctcg
      241 ttctcgccct tgatccggtg aatatggtct gcctggatac gcaaaggcgt aaaaagcaaa
      301 cgattcgcat gaccgtaatt actatccggg cttgtcggtg gaacgcaacg ctcgtccacc
      361 cagaagaaac ggatgttatt ccagtcaatc ttatccttat actcatctac ccagagggaa
      421 aacatatgct tcgccgtctc ccctcccgag agcgctaggt taaacggagc gaagtctttc
      481 cggcgaatca tcgccatcat atcctccgtc atcgaccgaa gcgcctcttt catctcatta
      541 tatctcttta tttccataaa attatcttct ttggcaggcg cagactttct tttccgcacc
      601 taaaataaca gtttcctccg gtccgtcctc gcccggctca tagaagaata agttcttcga
      661 accctcctct ttccaatgga gcaagatcgg atcgataaat ttccagctag cctccaaagc
      721 gtcgctacga gcatacaggg tggaatcgcc cagcatggca tccagcaaca gacgctcgta
      781 agcgtcagga agatagctct tcgagaggga atcgtagcgg aagtccatgc tgacttgctt
      841 cacctcgaaa ccggctcccg gcattttcag cccgaacttc aaggatatac tctcgttcgg
      901 ttggatacgg atggtcaatt tattgcagga acctcccgaa cattgaccga caaacagttg
      961 atggggcgta gacttgaagt ggatcactac ctccgatgac ttctccggca acttctttcc
     1021 cgtatagaaa tagaagggca caccgctcca gcgccagtta tcgatgaaga atttcatcgc
     1081 cacatacgtc tcggtattcg agtcggaagc tacgttcttc tcttcccgat aaccgatata
     1141 ttgtccgcgg acaaccatct tatccatatc caacaccgta tacgggcgta tggagcggaa
     1201 tactttcacg atctcgtcac gaatcggttc cggctcgaat atagagggag attccatggc
     1261 gataaacgac atcaattgca ttaagtgatt ctggatcata tcccgcatcg ccccggctcc
     1321 atcataatat ttccctctat tctccacccc caaagtctca gtagcgctga tctcgatgga
     1381 atcgatataa ttatgattcc acaatggctc gaaaataccg tttgagaaac gcaataccaa
     1441 gatattctgc acggtctctt tccccagata atggtcgata cgataaatct cctcctcatg
     1501 gaagatatgt cgtaaatgat cgttcaactg gcgggcagac tccaagctgg taccgaacgg
     1561 cttctctacg atgatccgcc tgaaaccatc tggagactcg gtcttgttca aaccgctctc
     1621 cagcaaacat tgcgggacga tctcgtacat caccggcggg gtagccaagt aatagatgat
     1681 cttatccggc aagtcatgtt tctcttgcaa gaactcgatg cgctcacgca atttgtagta
     1741 ttcatcggcg ttcatggaat cgaaggcgag gtaatagaca ttctccaaga agtcatcgat
     1801 caagccctcg tcgtaagtct ttcccttctg tgcctccaag atatgcgtat gttgctccgc
     1861 acggaactcc tcatcaccat aagcggtacg ggcggccccc aagatgcaga agcggtcggg
     1921 cagcaagccc cggacatata actcgaacaa agagggaagc aacttgcgac tggtaagatc
     1981 gcccgacgcc ccgaatataa ctaataattg attatctgct ttcttcatac ctttatacgt
     2041 tataagttcc agaaaccgtc tttcctccct cacccgtcca gttggtatgg aaaaacttac
     2101 cacgctccca atcgacccgc tcataggtat gagccccgaa ataatcccgc tgagcttgaa
     2161 tcaggttagc ggcagaatgt ggggtagaca atccatcgaa ataactcaac cccgagctca
     2221 ttgccggcaa agccactcca tgcaaggcac cctcggctac cacttgccgc caagccaaca
     2281 aggaagactc gatcttttga ataaagaact catcgaataa gaggttctcc agattccggt
     2341 tcttctcata agcctgcgta attttctcca aaaagacaga gcgtatgata catcccttcc
     2401 gccagatctt ggcgatcgta ccgtaatcca actgccaatc atatcgcttg gaggcttggc
     2461 acaacaaaga gaatccctgt gcataggaaa ccaacttagc ggcatacaaa gcctgcttga
     2521 tctctttctc cgagatcaag gtctgcccca gcacgccact cttcggataa agcgaggacg
     2581 cttttttccg ttcttcctgc atggaagaaa gcatacgggc ataaacagcc tcggtaatca
     2641 acgtcagcgg atcattctcg tccatagcgg cgatagcgct ccatttaccg gtgcccttct
     2701 ggccggcggc atccaatatc ttatctagca gatagccctc tcccgcctcg tccttgaagc
     2761 ggagaatatc ggccgtaata ccgatcaggt agctatccag ctctcccgtg ttccaatcct
     2821 caaagatacg agccaaggcc tcattgtcca gatccagacg attcttcaat aaggaatacg
     2881 cctcggaaat caactgcata tctccatact cgataccatt gtgtaccatt ttcacgaaat
     2941 ggccggctcc acccggacca atccattggc aacaaggcgt cccatcctcc agcttggcgg
     3001 cgatgctttg caagacatcc ttcaccaaag gccaagcggc aggcgagcca cccggcatca
     3061 cggaaggtcc gtacaaggca ccgatctccc ctccggagat tccggtacct acgaagtaca
     3121 tcccatgcgc ctccatctcc ttcacccgtc gttccgtatc atggaagtcc gagttgccac
     3181 catcgataat cacgtcaccg ggtgataagt aaggaatcaa ttgagccatc agctcatcca
     3241 ccggggcacc cgcttttacc atcagcatga tcttgcgagg acgctcgata gactcgacaa
     3301 attcctgtat cgtatgggtt cctataaaat tctttccttt tccacgaccg ctcatgaagc
     3361 ggtctaccac gccttcctct cccggcgctg tacgattata aacggataca gtgaacccct
     3421 tgctttccat gttcaacgca aggttttctc ccatcacggc caagccgatt aatccaatat
     3481 ttgatgtttt catatttatg tttttatttt attaatccaa atagatcatt taaagcctca
     3541 ctcatcgacg gatgggtgaa tatcgaatcc cggaggaacg tgtaatcttg cccgagacgc
     3601 atcgccaagc taaccgtatt tatgacttcg ctggactcgg cgcagaataa ggtacatcct
     3661 aggatcttcc cggtatccgc atctaccacg gctttcagta agccatccgt ctgctcgatg
     3721 gtacgggtac gaggcatggc ggcggcgggc aggctggcca cctttatatt tttctccatc
     3781 ttacgggctt gcgtctcgtt caacccgaca tgggccaacg gaggatcgat gaatacggaa
     3841 taagccactg cttcccgatc gtccaagctc cggaaaccat taccaaacag ctcctcccgg
     3901 ataatacggt aatcatccaa agataggtag gtgaattgca atccaccatg tacatccccg
     3961 atcgcccaga tattagggat attggtacgc aacttactat ccacctcgat agcgccacga
     4021 ttagtcgtct gtattccggc ggcttgcaga tttaggcttt ccgtattcgg tttacggccg
     4081 gtagccaaaa gcaccgcctc ggcatccagc cgcaaggtat ctcccgagat agcgttacgg
     4141 cagatcaccg tagcccgctc ggcatcctgc tcgatcgtct gcacgaccgt attcaaatga
     4201 atggtgatcc cttttttctc tagcgtagac ttcaccgaat cggcgatgtc ccggtcctca
     4261 cgagggataa acacctcccc tgcctccaag atcgttacct tcgatccaaa accggcgaac
     4321 atggaagcga attccagccc gatatatccg cctccgacaa taaccagatg ccgtggcagt
     4381 ttctccagtt ccataatgga agtacttgta tatacgtaag gattatcctc gataccgctt
     4441 atcgtaggaa taatcgtcgt ggctccggta ttgatgaata tcttctcgcc ttccagcaag
     4501 aaagagtccg tatccgtttt cacgacaatc tcataagggg aacgaaaaga agcctctccg
     4561 gtatagaccg ttacggtctc ccgatcatcc agattcttga aattcttctc acgaagcaaa
     4621 gaggtcagtt tctccttggc gaggatagca tgtttaaact cctccgcata ttgctcgaag
     4681 gtagaaggtc tgcgataccc tgtcacttga gcgtaatgta caagcgcttt cgtcggtata
     4741 cagccgatat tgatacaagt acctccgtac atacccgtcg aacgctccac cactgctaca
     4801 ttccatccat ggttggccaa atccgccgcc aaggtttttc cacctttccc aaaaccaata
     4861 ataatcgcgt cgtacttttt catctctgat ttatcttctt ttcgttagac attaaaataa
     4921 cattcgtttt aacctaattg ttgcgaattt catatcgcaa aaatagctcc agcccctatt
     4981 ttacaaaatg gctgttcaac ctataagttt agccattttt cccgaaacaa gaaaataacg
     5041 aacaaatacc ccctattttt tgttctttac ctataatatt tataccctat gatcacaaca
     5101 cttataatac tggccctatc agccgttttc tttgttaatg gaaaattacg ttccgatctt
     5161 gtcgctctat gcgccctcgt cttattaatc gtattcaaca tacttacacc cgaagaagcg
     5221 ctttccggct tctccaatcc tatcgtcatc atgatggtcg ggttatttgt cgtaggagga
     5281 gctatcttta aaacgggatt ggccaagatg atcagcagca agatactccg tctagcggga
     5341 aaaagcgaat tgaaattatt catattgatc atgatggtca ccgcttttat cggggcgttc
     5401 gtcagtaata cgggtaccgt ggccctcatg cttccgatcg tagtgagcat ggcggcaagc
     5461 gccaatatca gtcccgggag gttcttgatg cccttggctt tcgctagtag catgggcgga
     5521 atggccacgc tgatcggtac gcctccgaac ctcgtggtag atgaggtgct atccaacgcc
     5581 ggattcacgg atctatcgtt tttctcgttt acgcctatcg gggttatttg tgtgcttatc
     5641 ggcttggtcg tcttgattcc cctaagcaaa ttcttcttgg taaaaaagga ggatggcaaa
     5701 gacacgaaga ctacaaccgg gcactcccca aaagagttag ccaagaaata ccaattatcg
     5761 gataatctat atcggataca gatcaggccc ggttcccgga tcggagggaa aaaattgcaa
     5821 gaattaaata ttacgcaggc ttataatctc tccattctgg agatacgccg gcagtcgtcc
     5881 tctcaaggac gtttccttaa aaccgtagac cagtccttag ccggcccaca tacggaatta
     5941 caggagaacg atatcctcta tgtgttcggc ccgttcgaga aagtaaacca attcgccaaa
     6001 gaacagaatc tggagcttac ggatacccac gtatccgaat atgttgaagg ggcggaggtt
     6061 gaaaagctga gcgttcggga gatcggtatc gccgaggtct tattaatgcc cgactcgaaa
     6121 ttgataaata aggcggtaaa ggactctggt ttcagggata aatattccgt gaatatctta
     6181 ggcatccaac ggaaagggga atatatactg aatgatataa aagatataaa gatgcatgcc
     6241 ggcgatatcc ttctaataca aggcacatgg gacagtatcg ctcgcatgag ccaaaagcaa
     6301 tcgcaatggg tggtattggg ccagccctta gaagaggcct ctaaagtcac tctggattat
     6361 aaagcccctg tcgccgcctt gatcatggtc ttaatgattg ccgccatggt attcgacttc
     6421 atcccgattc ctccggtagc ggcggtaatc atagcgggaa tattgatggt attaaccgga
     6481 tgtttccgta acgtggaaga ggcttataaa acgattaatt gggaaagcgt agtcttgatc
     6541 gccgccatgt tacccatgtc gctagcctta gagaagacag gcgcctccaa tcttatctcg
     6601 gagaaattgg tgagcggact aggcgattac ggaccgctcg tcttgatggc cggaatttat
     6661 ttcaccacct cgctactgac catgtttatc agcaacacgg ccacggcggt actggtagcc
     6721 cctattgccc ttcaatccgc catagccatc aacgttagcc cttatccgtt cctgctggcg
     6781 gtgacggtag gtgccagcat gtgcttcgcc tcccccttct ctacgccacc caacgcactc
     6841 gttatgtccg ccggaaaata tacatttatg gactatgtaa aggtggggtt gcctttacaa
     6901 atcgtgatgg gaatcgttat ggtatttata ttacctttat tattcccatt ctaaacattc
     6961 gcacacgcat tttagtttta tatttgcagt ttgtaaaaca gtacaagaaa atttatggat
     7021 ataccgttta aaccgattag gttagaagac aaagagatca taacctcatt tacatttccc
     7081 agcgattatc gcaattgtga tttctcattc gcgaacatgt gcagttggcg tttcttatat
     7141 gacagtgaat tcgctatcgt ggatggctat ttattaatcc gtttcatgat cgaggacaag
     7201 agccgtttcg cctatatgat gcctgtcggg gatggagatt tagcgggtgc cgttcgtttg
     7261 ctggaagagg attccttaaa atatggacat ccgctctgta tgctgggtat cacccccgac
     7321 gccaaggagc aactggaagg cgcacttccc ggaagctttt tttatatccc agaacgggat
     7381 tatttcgatt acatttattt acgggaggat ttagcgacct tacggggtaa gaaataccaa
     7441 tccaaacgta atcatatcaa taatttcaag aaacaatatt cgtacgagta tgtccctatc
     7501 acgccggata tcgtccccca atgcctaaaa ctggaatgta aatggtataa ggcgaacaat
     7561 ggagataatg acgaggaaga gcttaatgac gaacgtcgct cccttaccta tgccttgcat
     7621 cattttgaca gcctaggcct gatcggtggc gctctccggg tggataacga gattatcgct
     7681 ttctctttcg gggcccccat caaccataat acattcggag tacacgtgga aaaagcggac
     7741 gtgaattttg acggagcata tacggtgatc aaccaagagt tcgcctctca ccttccggaa
     7801 cagtatactt acgtgaaccg ggaggaggat ctcggcatac cggggttgcg ccaagcgaag
     7861 ctttcttatc agcctaccat actattagag aagagtgccg caataaaaaa gcaacttacg
     7921 caaactaaat aaattatgga caagaaacaa caaatcgtaa acttatggcg tacctgcttc
     7981 ggggattccg aggcatttat cagcctttat tttgatcgtg tttacaagga cgagaacgca
     8041 atgaccatcg agaaagacgg taaaatagtt tctgccttgc agatagttcc tcatacgatg
     8101 acttatttgg gtaccgagat ctcggtaggc tatatctctg gggcgtgcac gactccggaa
     8161 gaaagagggc aagggcttat gcgacaactc ttgcaagaga cattcgagga aatggaacgg
     8221 cgtgagatcg ctatctccgc cttaatccct gccgatcctt ggctattcga ctattatagg
     8281 gaacagggtt ataccgaggc attcgattat tccgtagaga catatatccg cccgaatacg
     8341 ccggttcaac tcccgaagat aacggttatc caaccggagg taccgacaac cgacgaattg
     8401 ttcgcttatt tcaaccgcaa attacgtgaa cgcccttcct gtatcttgca ctcgcaggat
     8461 gatttcatca cgatacttcg tgatctgcaa ttagataacg gggggatgta cacggccttg
     8521 gacgagaacg agaaggtggt tggcatggct ttcgcactgc ctcttgaggc gggtacagcg
     8581 ccgtccgaca aaaagctttt tatcaaggaa cttctttacg actcggaaga gatcaaggaa
     8641 ttactattgc aagagcttac cctgcaaaat aacatatcgc aagcgacggt caatacccct
     8701 cccacccctc cgggtacctt acctatgggt atggcccgca tcatcgacac gaaacgcatg
     8761 atccacctct ggctatccaa acaacacgaa agccctgtct ccaaaaaaga tttggaacaa
     8821 atggataacc aaacgctaac acgacagttg atgggttatc aggggaggat ggcttatatg
     8881 agtttgatgc tggattaata gaaatgaaaa acggattgct aaggataaag ttcccgcaat
     8941 ccgtttttat tcttaaatct atttactgtt tacgacaaat aaaattatca tttagatgct
     9001 atgatcactt atctttagca gaatctcctt ggtaaagaag atcattgaca cctaaagtat
     9061 accaatccaa aacatctttt cctccagact tggcccaatt cataaattga ggatatgcat
     9121 ccataataga aataccttct ctaggatatg aatcaaaaga tgatttaggg atcatcaatc
     9181 cccacatcat attattaaat tcctctgttg aattatcaat attctcatta tacttatatc
     9241 gataatattc atcacttgtt aaggccgtgg ctgcttgttc cgtccctaaa aaaccaacta
     9301 tatggacctc gttcttttta ttcttattag gatcacccca aacaataaaa acgtttaagt
     9361 tgttagcatt cacaactccg ctcatgccat tcacatctac ttctatcaag ctttcacgtg
     9421 cttcacaagt cttattatat gtatttatta tttgacctgg ctcgctattc atgaactcat
     9481 gcgcctcttt tccttccaat aaattaataa ccttgtctgt tccttggatc ttcgcaaaag
     9541 catataaaga tttcgttgca cctacagccc taacacttgt tgataaatat acagtttttg
     9601 cattaatacc ttcactgcta gcctctgtcg tattcatgat gctgacaatc ataaccaagt
     9661 cattcatatc atagtcacca aaattaggcc aattgtcttc aaataaatag acataagctt
     9721 ctgtcttatc atattcaggt ttatactcag gcgtctcgga ttcgtctgta aaaggctcat
     9781 ctttactgta attgatatcg ccaaaacaat caccggatat atttacaggg catttattgc
     9841 caaccactct taacgcacca ttcttattag ctgaataatt tacttcactt tgcgcataag
     9901 tatataaatc actccagaaa aagcctgtta tctgaacaga tgtataatcc aatacaccat
     9961 tcaccttaaa caatttggca ctatttccat ctccatattg attggcatcc gcatcctcta
    10021 caactaagga tacaggacct gtttgagcag gattcaacgc atctgtctca aacaaggaat
    10081 gttccgccat cgatattttc gtatcataac catatataaa attcccggaa attacagaag
    10141 aaccccgatt taaatataat ccggaagcag atccatcaaa agagaaagta ccaaccttta
    10201 ccaaacaatg attatgaagt tcacctccat tcaaatgcat tgagtttaca gtaatttccg
    10261 aattcgtatg attataaatt gaactatgtg gcgaaggtag agtttctatt ctattaatat
    10321 ctactttacc catattaacc aattgagaat ttccatcaat tttcagaaca gccttagagc
    10381 caattatctg acctccatga aaaactacaa tttgactgtt ttttgtcaat ggtgaggctg
    10441 aagaagctaa atccaaggta gcgccgctaa aaatataaag agtgtagttc tcgttatcag
    10501 ggaaaacgac attgttgacc tttccgctcg taattttata actcttattt ttatcaagag
    10561 tcataccact ccgtagctct attacatctt tcatctcagc ttttttatcc aacttctcaa
    10621 tttccttctc cgaaagcggg gtgagccaac gtgttatttc ttgatcacta atcccgctgt
    10681 cactacgcaa aaaagatttt gtaataactg gatccgtata atccaataat aaatcgccat
    10741 ctttcacctc taagcttaca acagtactat acccttgtgc atccgttttc ttaatataaa
    10801 tatattcttg agtcttaggt aaagccaaat caacaataaa tggattcctt gagtttgttt
    10861 tacctccaac atagaaaaca gaattaggat cagtgatagg gtccgaacca aatacttcta
    10921 tcgtataata acgtttcccc tcatattcat ccaagacttt aacagtcaat ttatggctag
    10981 cctttgttga ataatcaaaa tcattcggaa taccatttgt actctcgtcc ggtctcggct
    11041 ttggatcggg atccggctta ggctcgtaca cgtccgctgt acatgcggtc atcagcaccg
    11101 caaacaggaa cagtgccatg aactttactt tcgtaaaaat acatctcttc atatgcttaa
    11161 tcattaaata tttcccctat aacatcatta aaaaaagaag ttgtatattt taatcaactt
    11221 attgagtatt atcaacagca aaggtagatt ttattataat gcgaagttct taaacgcaca
    11281 aatattatca catcaattaa ctataattaa taatgcccca aagaaaacac ctttgataaa
    11341 tagacaatat ttatttcatg ccatgttaaa aaagaacaat aaaagactat tcaccctact
    11401 ccaaccattc aatcagctta tcagccaaag ttactgttcc cggcaaaggt ggttggtgcc
    11461 gatgtggaga aggcccctag cgattttctc ttggcaataa catgccatct ggcaatttga
    11521 caaaatgaaa accaaagtct cggagaatcg attttttcgg gcaaaggtac ggattgctcc
    11581 caaatacgag aagaaaaaac agcattcgtc tcgttgatag acgaatactg aaaaatagcc
    11641 tttcgctcca gagaaattaa ttcatcatat ctcatatttt gaggcaagaa aagggtaaaa
    11701 gcagtgttac gatagggtta tagcacggta agaatgccca ttcatgagta ctcataaccc
    11761 tatgcacgac cgctcataat gcctaacgcg agtatcggca ttgggcaata cgacctatcg
    11821 caacaggttt cgccacctat cgtgtacaaa atcggcccct ttttcaagaa aaagcgtgtt
    11881 tattgccacg cctatctcat tatcttgtca ctttcgcacg aagggtatgt caacatattc
    11941 gtataatatg aagcaaatag tcagaataag cttctatttc gcaacagacc catcatacaa
    12001 gccagaggct cccaatacgc cttaagcact cacataaaac acggaatttt caatccaact
    12061 gataaatctt cagcttattg taaagcgtct tccggtcgat gcccaataac tgggccgcac
    12121 gagtcttatt attgccgcac tcttggaggg ccttacggat aaggtcacgt tcatgctcca
    12181 cgttcttaag ctggatgttg gtgtgcgaag agaggttctc cgtcagttcc tccggaagtt
    12241 ccttgcgggt gatgtatcga ccggtcgcca ataaggtagc gtacttgata acgttcttca
    12301 tctgccgcag gttacccggc caagaatagg attggaacaa ttgcatggta tcgttgtcga
    12361 aaccgatgat atccttacgg agctcgctat tcgccagatc gaggaagtgg ttggcgaaca
    12421 agagcaaatc ctcttttcgc tctttcaagt ccgggatacg gatcgtgaac tcattgatac
    12481 gatggtacag gtcctcacgg aaatctcctt tctcgatcgc ctgccgcaag ttctcgttcg
    12541 tcgcggatat caagcgcacg ttgatagcga tctcctgatt gctcccgatc ggctttacct
    12601 tgcgctcctg tagggcacgc aatagctgaa cctgtacctc atacgtcagg ttcccgatct
    12661 catccaaaaa tatcgtaccg ccttgagccg ccacaaacgc cccagtcttg ttctcgatcg
    12721 cccccgtaaa agaacctttc acgtggccga agaactcgga agccgccaat tccttgggga
    12781 tagcgccgca atccacggcg acaaacggag ccttgctacg attactttgc tcgtg
//
LOCUS       DBMDTB010000105        12733 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_1516_length_12733_cov_10.988917, whole genome shotgun
            sequence.
ACCESSION   DBMDTB010000105 DBMDTB010000000
VERSION     DBMDTB010000105.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 12733)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 12733)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12733
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1516_length_12733_cov_10.988917"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..770)
                     /locus_tag="ACZPB4_14030"
     CDS             complement(<1..770)
                     /locus_tag="ACZPB4_14030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HIR1099369.1"
                     /translation="MKATEKTFNGLRISGFLALFLILALSGLSCYLIAGINETWSVIT
                     GIVGLCLLAVCLLGLMEIEPNNAQVMLFFGKYKGTITDNGFFWVNPLYSKKKITLRAR
                     NLDVPPIKVNDKVGNPVMIGAVMVWKVKDTYRAMFDIDSSSISISSNKSFISMGESSE
                     LSQRMQNYENFVQIQSDAAIRKIAGMYAYDYNESKDPVTLRSDDGEVAQKLEEELNSR
                     LAIAGIEVLEARINYLAYASEIAGVMLRRQQAEAIIAA"
     gene            906..2909
                     /locus_tag="ACZPB4_14035"
     CDS             906..2909
                     /locus_tag="ACZPB4_14035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HIR1099370.1"
                     /translation="MDFQLDTNNKEFQDALQLITHTRQSVFLTGKAGTGKSTFLKYIC
                     NHTKKKYVVLAPTGIAAINAGGVTLHSFFKLPFRPMLPDDPDLSLSHGRIFEFFKYPK
                     EKRKIIAEVDLIIIDEISMVRADIIDCVDRILRVYSGNMRLPFGGKQLLFVGDVFQLE
                     PVVPSDQKEILSLFYASPFFFSARVFKDINLVPIELQKVYRQTDSVFINILDRIRNNA
                     ARKQELDTLNGRYFPSFEPQNEDMYITLATRRDQVDFINEKKLAELPGEEYVSVGKIE
                     GDFPESSLPTQLNLSIKEQAQVIFIDNDYERRWVNGTIGMVSGIDENGNVYVLLESGV
                     EHLVEPTSWRNYKYKYNEKEKRIEEEIVGTFEQLPIRLAWAITVHKSQGLTFSRVVVD
                     LTGGVFAGGQTYVALSRCTSLEGLVLKSKISSRDIFIRKEIVEFSQIFNNQALIEKSI
                     KESEAELQYGRAAQGFRQGNMKEAVEAFAAAVSKRNELDNPMVQRLLRLKLQALNSQK
                     AQIKALREELHSLRETQKEYAHEYYLMGNECITKAHDANAAIRCFDKALNLNPNYVEA
                     WVRKGVTLLDIGEDYDAQVCLNKAVKLSPKSFKARYNRGKCLLKLKYYDEAILDFQQA
                     VSIKPKHAASHEYLAEGFRAIGEDELAQRHQDIADALRGGEDI"
     gene            complement(2970..6260)
                     /locus_tag="ACZPB4_14040"
     CDS             complement(2970..6260)
                     /locus_tag="ACZPB4_14040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA];
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HIR1099371.1"
                     /translation="MSRHLQTLFLLAVLSFLFVIPTQAQVTTASMSGTVMFQDEPVIG
                     ATVLAVHEPSGTNYGTITNVDGRFSLQGMRTGGPYKVTISYVGYQSAVYSGITLQLGE
                     NYNLNVKLKESSETLDEIVITAAKTKFNTEKTGATTNISSSQITSLPTINRSISDIAR
                     LSPYASDMSFAGGDGRSTNFTVDGANFNNNFGLSDNLPGGGNPISMDAIEEVQVVIAP
                     FDVRQTNFIGGGINAITKSGTNTFKGSAYTYFQNQNMRGNSIDGEDLGARAKESKTIY
                     GATFGGPIIKNKLFFFANVEVEKQPQQVIKWRARTEGEQPDENNYISRTTLSDMQKVS
                     DFLRDKYGYDTGSATNFPADEKNLKLLGRIDWNITNGHKLSVRYNYTKNTAWNAPNAN
                     SMDGGSGSRLYNTSRVGYQSMSFANSMYSQDNKVSSVSADLNSRFSDKISNQLLFTYT
                     DIEDMRGTNSSPFPFIDILAGKDAEGNQIMEPYMSAGYELFTYNNGVKNKITSVIDNF
                     TYFAGDHKITAGISFEHQLASNAYMRNGTGYYRYSSLDDFLNGAAPETFAWTYGYNGV
                     SDPKAQVTFNQIGFYAQDEWNIRPNVKLTYGIRFDDLIFDNSDLQRNDAIYDLDFGGK
                     HIDTGKWPKSRMQISPRVGFVWDVFKDNSLKVRGGTGIFTGRLPLVFFTNMPTNSNMV
                     QNAVVFGTKYENGIAVSHDSRLDQLAGGMITNVDDAIKKFGLPTTIENPVAGSKISGV
                     KDNFKMPQIWKTSLAVDYQLPTSFPLSVTGEFIYNKNINAVTLENINIKDPSNWEHFN
                     GADNRLIYPSDYTYVSGKNAVVLTNTSKGHGYTANVTINAQPVEDLNMMLAYTHTESK
                     EISGLPGSDPVSTWQGMLTIDGPNFATVQRSRYVVPDKVIAAVNYNLPFRHKGLLRKT
                     SLNLFYSGYSASGYSFAYTNDMNGDGINNDMMYIPKDDSEIKFKNEADRTAFWNFVDQ
                     DSYLKNHKGEYAEAYAARAPWVHRFDLRITEDFSFKAGKTEHHFQLSLDFMNIGNMIN
                     SKWGVMKNASSSNGCRILKYEGMDDNKTPIFSMYKINGEYPTETYSYNRIYTECWKMQ
                     VGIRYIFN"
     gene            6697..10050
                     /locus_tag="ACZPB4_14045"
     CDS             6697..10050
                     /locus_tag="ACZPB4_14045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA];
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HIR1099372.1"
                     /translation="MRKTYLLLTLLLLCVGISIHAQVTTASMSGKVTDISSEAMIGVN
                     IKATHTPTGTEYYTITQPNGSYSFNNLRIGGPYVVEFSYIGYNTESRTGINLVLGEDL
                     KLNVVMREDTQALDEVVVVADKNPIISGSRTGAQEIITREKMDKLPTINRSLDDFVKL
                     TPMSSGKNFGGVSYRFNNVTVDGASFNNSFGLASALGASGTEPISLEALEQVQVMIAP
                     FDVRNGGFTGAGINSVTKSGSNEFHASVYMYTKSPSMMGYRVKDETIGVSEFSNHQYG
                     ISLSGPIIKNKLFFFINGEMDRQEEPISYTTANSAADATVLQGLSDFLGDELGYNPGK
                     FDVNKTNTQADRITARLDWNINSNNVLSLKYYYLKSFNTNNPSTSGAPNNGRGPNAFA
                     IPFSSSFYRTNNNFNIWMADLNTTINDRMSNYLKIGYSRLRDYRDMDGGYFPQVDILD
                     GDNNAYTTFGTEANSYNNQLNSDIWQIQDNFLMNFGKHQITVGTQSDYRAFKNGFAQN
                     YPGSWVFNSVDDFKFNVLATKQYMAAHNGSVQGFDIREFNPKDFGFGSNVTGITNSSS
                     TGYQYYAQRYSMTDDFPFAEINVFQLGLYAQDKWTVSDKLNLTLGLRIDVPFFMTDLQ
                     SNDKVAAETYRDGIKIDVSKYPNAKPQFSPRFGFNYKPFDDENGSLQIRGGTGLFTGT
                     PPYVWISNQAGNNGVLFGDLNVRAVKDKNDNIISDGRPSLGFTGNMDTYKPAEGSATR
                     SDIAITDPDFKYPSLWKSNIAADYKFGDGWVATVELLYSKDINAIYHDNIGLYRTEQF
                     VNDGGAGNARPYYNGYYSDREGNQKAANHVVMLRNTSKGHSLYTTFQLQKNFVDGILK
                     GLYLNGSYSFGQSRGVTDGTSSVATSAWKYRAALDGNAEEVGYTAGSFDGRLLLSASY
                     TANWSKYAATSFGLIYQRYRPFRYSYCYNGDANGDSQFSNDLMYIPANFDEVKDHLLP
                     GDFDSQEDAWKAMNAFIEQDPYLSKHRGEYAERNGAVAPFANQLDLSVSHDIKIYQKN
                     GRSHTLRFSFNIANFLNLLNRNWGVVQTTVLGNQQYQFLTIPKGQGPSAANNYTLKYT
                     MAKDLDETFKDNLNDVSRWQMQFGIKYIF"
     gene            10130..11335
                     /locus_tag="ACZPB4_14050"
     CDS             10130..11335
                     /locus_tag="ACZPB4_14050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HIR1099373.1"
                     /translation="MWNNRIEFLLVSFFCICSLAFTGCQTKKQSDRYVVVLSMDGFRS
                     DYPSRAHTPTLDSLANVGVRSTFRPCYPSVTFPNHYSMATGLHPDHHGLVNNFFYDAE
                     LDSSYRMGNLDPRFYGGEPIWNTAERQGVRTASFYWVGSEVPLASGQPSIWKPFDKSV
                     SFSDRADSVISWLKLPEDIRPHLIMWYMEEPDAIGHSATPDSSATLDVVENLDKVLNH
                     FFTEARKLDIFDKIDFIVLSDHGMATYYPERYVNLNDYLPRDSFDYVFDGVPTLLYPK
                     KTYVDTAYAILQKVPNITVWKKNEIPEKLVYGKNPRVSDLVVSPHIGTYVQFREKSSP
                     RYAATHGYDNFTPEMEAIFYAAGPSFKKHVEVPQMANVNLYLMIARLLNIQPAPNDGD
                     SAVVQRLFK"
     gene            complement(11421..12269)
                     /locus_tag="ACZPB4_14055"
     CDS             complement(11421..12269)
                     /locus_tag="ACZPB4_14055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HIR1099374.1"
                     /translation="MNPTFGASILSWIPPMWTPEGGLFAIQQASAAGFDLLEILLPPS
                     MEFDAPTVKRQLKQHGLKATCSLNLPKEAHIPFYPKKATCLIKEALDKASELEVDYLG
                     GVLHSGIGVFSGKQRTREEENTLCEVWAEVAEYAARSGITIGIEPINRYESYMCTSAE
                     EVLRFIKRVNAPNLSLHLDTFHMNIEETSFYEPVIAAGSRLRHIHMTESDRGMLGEGN
                     VRWDDLFRGLQEIDFNGNLVLENFSNSVPGMAVAVSLWRPSKYNADELAKGSLAFMRK
                     MTCEHQ"
     gene            complement(12375..12590)
                     /locus_tag="ACZPB4_14060"
     CDS             complement(12375..12590)
                     /locus_tag="ACZPB4_14060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HIR1099375.1"
                     /translation="MTKGSIGLNAGAIWNLLSDGQHWSFEALRAKSALTDADLWSAIG
                     WLARENKIEIDNTSSHPIFCPGTNFYF"
BASE COUNT         3455 a         2507 c         2972 g         3799 t
ORIGIN      
        1 ctggcggcga taattgcttc cgcttgctgg cggcgtaaca tgactccggc gatctcggaa
       61 gcatacgcta agtaattgat acgggcttcc aatacctcaa tacctgctat cgccagacgg
      121 ctgtttaatt cctcctccag cttttgagcg acctccccgt catcggaccg taaggtcacg
      181 ggatctttgc tctcgttata atcataggca tacatgccag cgatcttacg gatggcggca
      241 tcactttgta tctgcacgaa attctcataa ttctgcattc gttgggataa ttcagaggat
      301 tctcccattg atatgaatga tttattcgaa gagatactaa tagacgaaga atcgatgtcg
      361 aacatcgctc tataagtatc cttgactttc cataccatca cggccccgat cataaccgga
      421 ttgccgacct tatcgtttac cttgatagga gggacatcta aattacgggc acgtaacgtg
      481 attttctttt tgctgtaaag cgggttgacc cagaaaaatc cattatcagt aattgtccct
      541 ttatattttc cgaaaaagag cattacttgg gcattattgg gctcgatttc catgagtccc
      601 aataaacaaa ccgctaacag gcagagtccg acgatgccgg tgattacgct ccaagtctca
      661 tttatgcctg cgattaaata gcagctaaga cccgatagag ccagtatgag aaaaagggca
      721 agaaacccag agattctcag tccgttgaat gtcttttcag ttgctttcat gatgatttat
      781 atttgatatt aatttgatat cacaaaataa gtgattttta tggagactgc caaatctttt
      841 gagggatatt attagagtga tctgtaaata ttttcatagc tttgtctcat ctaaaaatta
      901 tatacttgga ctttcagtta gacacgaaca ataaggagtt tcaggatgcc ttgcaactga
      961 tcacccacac tcgccagtct gttttcctga cagggaaagc agggaccggc aagtctactt
     1021 ttttgaagta tatttgcaat catacgaaga aaaagtatgt ggtgctggct cctaccggaa
     1081 tagcggccat aaatgcgggc ggcgttacct tgcattcctt tttcaagctc ccttttcggc
     1141 cgatgttgcc ggatgatccg gatttaagtt tgtctcatgg tcgtatcttt gagtttttta
     1201 agtatccgaa ggagaaacgg aaaattatcg cggaggtcga tttgatcatc attgacgaga
     1261 tatcgatggt gagggcggat attattgatt gtgtagatcg tatcttgagg gtctattccg
     1321 gtaatatgcg attgcctttt ggcggaaagc agctattgtt cgtgggagat gtcttccagt
     1381 tggaaccggt tgttccgtcg gatcaaaaag agatattgag tttgttctat gcgagccctt
     1441 tctttttctc ggctcgtgtg ttcaaggaca ttaatttagt gccgatcgag ttgcaaaaag
     1501 tgtatcgcca gaccgattct gtttttatca atatattgga tcggattcgt aataatgccg
     1561 ctagaaaaca ggagttggat acgttgaacg gtcgttattt tccgtctttc gagcctcaga
     1621 atgaggatat gtatatcacg ttggccactc gccgggatca ggttgatttt atcaatgaga
     1681 agaagttggc cgagcttccc ggagaagagt acgtctccgt gggaaagatc gagggggatt
     1741 ttccagaatc ctcactacct acccagctga atttatccat caaggaacag gcgcaggtta
     1801 tttttatcga taatgattat gagcgtcgtt gggtgaacgg gacgatcggt atggtatcgg
     1861 gtatcgatga gaatggaaat gtttatgtct tgctggagag cggtgtagaa catttggtcg
     1921 aacctacctc atggcgaaat tataaataca aatataacga gaaagagaaa cggatcgagg
     1981 aagagattgt cggtacgttc gaacaattgc cgattcgttt ggcttgggcg atcacggtgc
     2041 ataagagtca aggcttgact tttagccggg tggtagttga tttgaccgga ggggtatttg
     2101 ccgggggaca aacctatgtg gcgttgagtc gttgtacttc attggaagga ttggtgctaa
     2161 aaagcaagat ctcttcccgg gatatcttta tccggaaaga gatcgtagaa ttcagccaaa
     2221 tattcaataa ccaagcatta atagagaaaa gtatcaaaga gagcgaggcg gaattgcaat
     2281 atggtcgggc ggctcagggt tttcggcagg gtaatatgaa agaggcggtc gaggcttttg
     2341 ccgccgccgt atctaaacgg aatgaattgg ataatccgat ggtacaacgg ctgcttcgtt
     2401 tgaaattgca agccttgaat agtcaaaagg cacagattaa ggctctgagg gaagaattgc
     2461 attcgcttcg tgagacccag aaagagtatg cacatgaata ttacttgatg ggtaacgagt
     2521 gcataacgaa ggcccatgac gcgaatgccg ctattcgttg ttttgataaa gccttgaatt
     2581 tgaatccgaa ttatgtggaa gcttgggtac gcaaaggggt tactttattg gatataggtg
     2641 aggactacga cgctcaggtt tgtttaaaca aagcggtaaa attaagtccg aaatctttta
     2701 aggcccgcta taaccgtgga aaatgcctat tgaagctcaa atattacgat gaagctattc
     2761 tggatttcca gcaggcggta agtatcaaac ctaaacatgc ggcttcccac gaatatctgg
     2821 cggagggttt ccgggcgatc ggagaggacg aattagccca gcggcatcaa gatatagcgg
     2881 atgccttgcg agggggagag gatatatgat gaaatagaaa aggcgagaaa atttatttcc
     2941 cgcctttttt atggagttat atctcttgat taattaaaga tgtaacggat accaacctgc
     3001 attttccagc attcagtata gatacggtta taagaataag tctcagtcgg atattcacca
     3061 ttgatcttat acatggagaa aattggagtc ttgttatcat ccatgccttc atatttcaag
     3121 atacggcaac cgttggaaga agatgcgttc ttcattacac cccatttcga gttgatcata
     3181 ttaccgatat tcatgaaatc aaggctcaat tggaaatgat gttcggtttt acctgccttg
     3241 aatgagaaat cttccgtgat acgaaggtcg aaacgatgta cccaaggtgc acgtgcggca
     3301 taagcctcag cgtattctcc cttgtgattc tttaaataag aatcttggtc tacgaagttc
     3361 cagaaagcgg ttctatctgc ttcattcttg aatttgattt cactatcatc tttcgggata
     3421 tacatcatat cattattgat accgtcacca ttcatatcat ttgtataagc gaagctatat
     3481 ccggaagcgg aataaccgga atagaacaga tttaagcttg tttttctgag cagaccttta
     3541 tggcggaagg gcagattata attgaccgct gcgattacct tgtcgggcac tacataccgt
     3601 gaacgttgta cggtcgcgaa attcggtccg tctatcgtta acattccctg ccatgtagat
     3661 acagggtcgc tacccggaag accggaaatt tctttggatt ccgtgtgcgt ataagccaac
     3721 atcatgttca aatcctctac gggttgagcg ttaatcgtaa cattggcggt ataaccatgt
     3781 cctttggatg tgttagttaa tacaaccgca ttcttaccgg atacatacgt ataatcagat
     3841 ggataaatca aacggttatc cgctccgtta aaatgttccc aatttgacgg gtccttgatg
     3901 ttgatattct caagggttac ggcattgatg ttcttgttat agatgaactc gccggttacg
     3961 gataatggga aggaagtagg gagctgataa tctacagcca aggaggtttt ccatatttgt
     4021 ggcatcttga agttgtcctt tacgccagag atcttagaac cggcaaccgg attctctatc
     4081 gtggtaggaa ggccgaattt cttgatcgca tcatctacat tcgtaatcat gccgccagcc
     4141 aattgatcca gacgggaatc atgacttacc gcaattccat tctcatattt tgtgccgaat
     4201 actacggcat tttgtaccat attcgagttt gtcggcatat tcgtaaagaa taccaagggt
     4261 aaacgtccgg taaatatacc tgtaccacca cgtactttta aggaattatc cttgaacaca
     4321 tcccaaacga aacctacacg aggggatatt tgcattctag acttaggcca tttgccggtg
     4381 tcgatatgtt tgcctccgaa atcaagatcg tagattgcgt cgtttctttg aagatcgcta
     4441 ttgtcgaaaa ttaaatcatc gaaacgtata ccataagtta acttcacgtt cgggcgaatg
     4501 ttccactcat cctgtgcgta gaatccgatc tggttaaaag taacctgagc tttcgggtcg
     4561 gaaacaccgt tgtaaccgta tgtccatgcg aacgtttcag gagcggcacc gttcaagaaa
     4621 tcatctaagc tgctgtaacg ataatatccc gtgccgttgc gcatataagc attgctagca
     4681 agttggtgct cgaaactgat accagctgtg atcttatggt cgccggcaaa gtaagtgaag
     4741 ttatcgataa cacttgtgat cttgttcttc acgccgttgt tgtaagtaaa taattcatat
     4801 ccggcactca tataaggctc cataatttgg ttaccttccg catctttacc tgccaagata
     4861 tcaatgaagg ggaaagggga agagttggtt ccgcgcatat cctcgatatc cgtataagtg
     4921 aaaagtaact gattggaaat cttatcagag aagcgactgt tcaaatcagc ggatacggaa
     4981 gacactttat tgtcttggga atacatgctg ttagcaaaag acatggattg gtaacctaca
     5041 cggcttgtat tatacagacg agagccggaa ccaccatcca tagagttagc gttaggagcg
     5101 ttccatgcgg tattctttgt atagttgtac cgtacgctca atttatggcc attcgtgata
     5161 ttccagtcga tacgacctag caatttcaaa ttcttttcgt ctgcggggaa gttcgtggct
     5221 gatcctgtat cataaccata tttatctctt aagaaatcgg ataccttttg catgtcggag
     5281 agtgtagtgc gagatatgta gttattctcg tccggttgct ctccttcagt acgagctctc
     5341 catttgatca cttgttgcgg ttgtttttcc acttctacat tggcgaagaa gaataattta
     5401 ttcttgatga tcggaccgcc gaacgtagct ccgtaaatcg ttttggattc cttagcacgt
     5461 gcgcccaagt cttctccatc gattgagttt cctcgcatat tctggttctg gaagtaagtg
     5521 taagcggaac ctttgaatgt gtttgtaccg gatttggtga tagcgttgat accgccacca
     5581 atgaagtttg tctggcggac atcgaacggg gcgattacca cttgtacttc ctcgatagcg
     5641 tccatagaga tcgggttacc gcctccggga agattatccg aaaggccgaa gttgttatta
     5701 aagttcgctc catctaccgt aaagttcgtg gaacggccat cgccaccggc aaaactcatg
     5761 tcggaggcat aaggagaaag gcgtgcgata tcggagatac tacggttaat ggtgggtaaa
     5821 gaggtgatct gtgacgagga gatattggtt gtcgcacccg tcttttccgt attgaacttc
     5881 gttttcgccg ctgtgattac gatctcgtcc aaggtctcgg aagattcttt caacttaaca
     5941 ttcaagttgt agttctctcc caattgcagg gtaatgccgg aataaacggc agattgataa
     6001 ccaacgtaag agatcgtaac tttgtatgga cctcctgtac gcataccttg taaggaaaag
     6061 cgtccgtcaa cgtttgtgat cgtaccataa tttgtcccag aaggttcgtg aaccgccaaa
     6121 acggtcgcac caataacggg ttcatcttga aacataactg ttccactcat actggctgtt
     6181 gttacctgcg cttgtgtcgg gatgacaaac aagaaactca gtacagctaa aaggaatagc
     6241 gtctgtaaat gtctgctcat aatttaaaat agttaatgta ataaaaactt tcgcaaagtt
     6301 atgggttatt ttttaatatc attgtatgtt tcttatttaa tacttgtttc atattcatga
     6361 agttgctgtg acggggcgga attgagtaat gtccttattc ggagatggat ggcttgtatt
     6421 ggcaaaacaa gagggttctt tatgaaattt ttaatttgat gattcttaac taacattccc
     6481 tgttgggcgg tgatttaaaa gaattataga cgcttttcct gcatattgtt ggattatgga
     6541 tgtggttggt tgaaaataat aatctggaga tctgtgtgag gaatgttaat gctatgaata
     6601 ttatatatag tttgtgacaa aaagagatat ctaatcccta tctttgcggc gatatacaaa
     6661 aatgttataa ttattttaaa tataaatact tcttgtatga ggaaaactta tctactttta
     6721 acgttacttt tgttgtgcgt gggaatatcc atacatgctc aggtgacgac ggcgagtatg
     6781 agtggtaaag tcacggatat atcatcggaa gcgatgatcg gagtgaatat caaggctacg
     6841 catacgccaa cgggtaccga atactacacg attacccagc cgaatggttc ttattctttt
     6901 aacaaccttc gtatcggagg cccttatgtg gtagagttct cttatattgg atacaatacg
     6961 gagagccgga caggaataaa cttggttttg ggtgaggatc tgaaactgaa tgtagtaatg
     7021 cgggaagata cccaagctct cgacgaggta gtcgtggttg cggataagaa ccccattatt
     7081 tcaggaagtc gtacaggtgc gcaggaaatc atcactcgtg agaagatgga taagctgcct
     7141 acgattaacc gttctttgga cgatttcgtg aaattaactc cgatgagtag cggtaagaat
     7201 tttggcggtg tctcttaccg ttttaataat gtaacggtgg acggtgcttc ctttaataac
     7261 tcgtttggtc tggcttctgc tcttggagct tccggtacgg aaccgatttc tttggaggcg
     7321 ctcgagcagg tacaggtgat gatcgctcct tttgatgttc gaaatggagg atttacgggt
     7381 gcgggtatta actccgtaac gaaatccggt tcgaatgagt ttcatgcttc tgtatatatg
     7441 tacacgaaga gtccgtctat gatgggatat cgtgtgaagg atgagacgat tggtgtttca
     7501 gagttctcta atcaccaata cggtatcagt ttatccggtc cgatcattaa gaataagtta
     7561 ttcttcttca tcaatggtga gatggatcgt caggaggaac cgatttctta tacgaccgct
     7621 aattctgcgg cggatgcgac agtcttgcag ggtttatctg atttcttagg tgatgagctt
     7681 gggtataatc cgggtaaatt cgacgtgaat aagacaaata ctcaagcgga tcgaatcacg
     7741 gctcgtttag actggaatat caactcaaat aatgtgttga gcttaaaata ttattatttg
     7801 aaatcgttta atacgaataa cccttctact tccggtgcgc cgaataacgg acgtggaccg
     7861 aatgcgttcg ctattccttt ctcttcttct ttctaccgga cgaataataa cttcaatatt
     7921 tggatggccg acttgaatac gaccattaat gaccgtatgt ctaattattt gaagatcggt
     7981 tattcccgtt tgcgtgatta tcgcgatatg gatggtggtt acttcccgca agtggatatc
     8041 ttggatggtg ataacaatgc ttatacgact ttcggaaccg aggcaaactc ctataataac
     8101 cagttgaaca gtgatatctg gcagatacag gataacttct tgatgaattt tggcaaacat
     8161 cagattacgg ttggaacgca aagtgactat cgcgccttta agaatggttt cgctcaaaac
     8221 tatccgggtt cttgggtatt taactctgtc gatgatttca agttcaacgt attggctaca
     8281 aaacaataca tggccgctca taacggaagt gtacaaggat ttgatatccg tgagtttaat
     8341 ccgaaagatt ttggatttgg ttccaatgtg acaggtatta cgaattcttc ttctacggga
     8401 taccagtact atgcgcaaag atattcgatg acggatgatt ttccattcgc cgagataaat
     8461 gtattccagt taggtttgta tgcccaagat aagtggacgg taagtgataa attgaacttg
     8521 acgttaggtt tacgtattga tgttccgttc tttatgactg atttgcagtc gaatgataaa
     8581 gtcgccgccg agacctatcg ggatggcatc aagatcgatg tttctaaata tccgaacgcc
     8641 aaacctcagt tctctcctcg attcggtttt aactacaaac cgtttgacga tgagaatgga
     8701 agtttgcaga tccgtggtgg tacgggactc ttcacgggta ctcctcctta tgtatggatc
     8761 agtaatcaag ccggcaacaa tggcgttttg tttggtgact tgaatgtccg ggcggtaaag
     8821 gacaagaatg acaatatcat tagcgatggc agaccttcgc taggttttac cggaaatatg
     8881 gatacttata aaccggctga aggtagcgct acccgttcgg atatagcgat tacggatccg
     8941 gactttaaat atccgagctt atggaaaagt aatatcgctg ccgattataa gtttggtgat
     9001 ggctgggtag ctaccgtaga gttgctgtac tcaaaagaca ttaacgctat ttatcatgac
     9061 aatatcggat tgtatcggac cgagcaattt gtaaatgacg gtggagcggg taacgcacgt
     9121 ccatattata atggctatta tagcgatagg gaaggaaatc aaaaggccgc gaatcatgtc
     9181 gtgatgctgc gtaataccag caaaggacat tcgctttata cgaccttcca gttgcagaaa
     9241 aactttgttg atggaatctt gaagggattg tatttgaatg gatcttactc tttcgggcag
     9301 tctagaggtg taacagacgg aacatcgtct gtggcgactt ccgcttggaa gtaccgtgcg
     9361 gccttggacg gaaatgcgga agaagtaggt tatacggcag gttcttttga tggtcgtttg
     9421 ttattgtccg cttcttatac ggctaactgg agtaaatatg cggcaacaag ttttggtttg
     9481 atctatcagc gttatcgtcc gttccgttat tcttattgtt ataatggtga cgcaaatggc
     9541 gattctcagt tctccaatga cttgatgtat atccccgcga attttgacga ggtaaaagat
     9601 catttgttac cgggcgattt cgatagccaa gaagatgcat ggaaagcgat gaatgccttt
     9661 atcgagcaag atccttattt gagcaaacat agaggtgagt atgccgaacg taacggtgct
     9721 gtcgctccgt ttgcgaatca gttggatttg agtgtttctc atgatataaa gatttaccag
     9781 aagaatggtc gttcacatac cttgcgcttt agtttcaata tcgccaactt cttgaatttg
     9841 ttgaatcgta actggggtgt ggtacaaaca accgttttgg gtaatcagca atatcagttc
     9901 ttgacgatcc cgaaaggaca aggcccgagt gcggcgaaca actatacgtt gaagtatacg
     9961 atggcgaaag atttggacga aaccttcaag gataatttga acgatgtgtc tcgttggcaa
    10021 atgcaattcg gtatcaagta tatcttctaa aaaaaatctt tcattagata aaatttaata
    10081 attagaagag gttcactatc tttgtggacc tcttttttaa tttaatgata tgtggaataa
    10141 tcgtattgag ttcttactcg ttagtttctt ttgtatttgt tcattggctt ttaccggttg
    10201 ccaaacgaaa aaacaatcgg atcgttatgt cgtagtttta tcaatggacg gtttccgctc
    10261 tgattatccc tcacgtgctc atactccgac gttggattct ttggcgaatg taggggttcg
    10321 ctccacgttt cgcccatgtt atcccagcgt gactttcccg aatcattata gcatggctac
    10381 cggattgcat ccggatcacc atggtttggt aaataatttc ttttatgacg cggagcttga
    10441 tagctcatac cgtatgggaa acctggatcc gcgattttat ggtggagaac ctatttggaa
    10501 tacggcggaa cgccaagggg ttcgtaccgc ttccttctat tgggtcggta gcgaggtgcc
    10561 tttggcgagt ggccagcctt caatatggaa gccgtttgat aaatcggttt ctttttcaga
    10621 tcgtgctgat tccgtgatct cttggctgaa gttgccggaa gatatacgtc ctcatttgat
    10681 tatgtggtat atggaagagc cggatgcgat aggtcattcc gctaccccgg attcctcggc
    10741 aaccttggat gtggtagaga acttggataa agtcttgaat catttcttca cggaagcccg
    10801 taagctggat attttcgata agatcgattt tatcgttctc tcggatcatg gaatggccac
    10861 ctattatccc gagagatatg tgaacttgaa tgattatcta ccccgggata gtttcgatta
    10921 tgtctttgat ggcgttccta cattattata tccgaagaaa acctatgtgg atactgccta
    10981 tgcgatttta cagaaagtgc cgaatataac cgtatggaag aaaaacgaga tcccagagaa
    11041 attggtttac ggaaagaatc ctcgagttag tgatctggtt gtttctccac atattggaac
    11101 gtatgtgcaa ttccgcgaga aatcatctcc ccgttatgcg gcgacacatg gttacgataa
    11161 ttttacaccg gagatggagg ctatattcta tgcggcaggt ccctcgttca agaaacacgt
    11221 agaggttccg caaatggcga acgtgaacct ctatttgatg atcgcacgct tattgaatat
    11281 acagcccgcc ccgaatgatg gagatagcgc tgtcgttcag cggttattta aatgatagga
    11341 cttcgcgcta ctttctaaat ggagatttac tgcacgggcc ttgcagtact actgtaaagc
    11401 cggttgcagt aattgatgcc ttattgatgt tcgcatgtca tcttacgcat gaaagcgaga
    11461 ctgcctttag ctagctcatc tgcgttgtat ttagatggac gccaaagaga tacggctacc
    11521 gccatgccgg gaacggaatt ggagaaattc tccagaacta agtttccatt gaaatcgatt
    11581 tcttgtagtc cccggaacaa atcatcccag cgtacgtttc cttcacccag cattccccgg
    11641 tcgctttcag tcatgtgaat atggcgaagt cggctgcctg cggcgataac cggttcatag
    11701 aaactagtct cttctatatt catatggaaa gtatccagat gcaaagataa attcggagcg
    11761 tttacgcgtt tgataaagcg caggacttcc tccgcagagg tacacatata actttcatag
    11821 cgattgatcg gctcgatacc gatcgtgatt ccagatcggg cggcgtattc ggcaacctcc
    11881 gcccatacct cacaaagcgt attctcttct tcccgtgttc gctgtttgcc ggaaaagacc
    11941 ccaatgccgg aatgtaagac acctcccaag taatcaacct ccagttcgct cgctttatcc
    12001 agcgcctcct tgatcagaca agtcgctttc ttgggataaa aaggaatatg cgcttctttg
    12061 ggaagattga gagaacaagt cgccttcaat ccgtgttgtt tcaattgtcg ctttacggtt
    12121 ggagcatcga actccatgga aggaggcaac aaaatttcca gtaaatcaaa accggcggca
    12181 gatgcttgct ggatagcgaa aagaccgcct tctggtgtcc acataggtgg tatccaagaa
    12241 agaatggaag ctccgaaagt aggattcata atcgtattgt ttttatttcg ttagggttac
    12301 aaagtaagtg tttttttgaa gatttcattg cgaagaaagt gaaatccttc gcaatgaaat
    12361 atcataaatg tcatttaaaa ataaaagttg gtacccggac agaagatagg gtggctgctg
    12421 gtattatcaa tttcaatctt attttctcta gcgagccaac cgatagcgga ccatagatcc
    12481 gcatctgtta gagcggattt tgctctcaac gcctcaaaac tccaatgttg gccatctgaa
    12541 agcaaattcc agatagctcc tgcatttaat ccgatcgatc cttttgtcat gataaaatct
    12601 gtttttatgt ttatggtata tagtgcttat attgttataa cagataatat ccggtaaaag
    12661 tatgttgcgt tgagataaat aatctaaaaa acaaaaatct cttgatgcgt tgaattttat
    12721 tccttgaagt cag
//
LOCUS       DBMDTB010000106        12198 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_1588_length_12198_cov_11.657022, whole genome shotgun
            sequence.
ACCESSION   DBMDTB010000106 DBMDTB010000000
VERSION     DBMDTB010000106.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 12198)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 12198)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12198
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1588_length_12198_cov_11.657022"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..1509
                     /locus_tag="ACZPB4_14065"
     CDS             <1..1509
                     /locus_tag="ACZPB4_14065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HIR1099376.1"
                     /translation="AYREGLDLLQKRGDNPKFEMQYMGNLIESYLRTDHFTEAEELLT
                     RYDEMIQDRERENEEQGTAFPVDRCRALMYVFYADMYVLQDKPKETLDALLKATPIVE
                     KTGDDYTEFCYNFVFAKYYYLIGMYERALNIIDKNKLTEEDIRTSELKVEILEALGRY
                     KEALAFSREVVEHTKMLHDEAFNRQINQLRTLHDLNNQEMQAYELQLREQQLHTQRLL
                     MIILLVVSIVLLVMLYIVYKSYRSARRYQRELMKDKEALVESERQLRTAKEIAEHANQ
                     MKSTFIANISHEIRTPLNAIVGFSELISDESISAGEKKEFFSIINNNSYLLLNLINDI
                     LDLSRLESGNMKFIIEKTSLSDCCRNALASVEHRVFPGVQLTYTPSEDPLHIQTDSIR
                     LQQLLINLLTNACKFTKEGEINLSYQIDEDKQHVRITVTDTGCGIPEDKQKVIFERFE
                     KVDEYAQGTGLGLSISQTIIEHLGGSIQLDPTYKHGARFIVLHPYNPLDNPS"
     gene            complement(1504..2268)
                     /locus_tag="ACZPB4_14070"
     CDS             complement(1504..2268)
                     /locus_tag="ACZPB4_14070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HIR1099377.1"
                     /translation="MKALIIEDEKAAVRNLMALLGEADPDIEVIDVLDSITDSVEWFQ
                     SHPMPELIFLDIHLADGSAFEIFGHVDISCPIIFTTAYDEYALKAFKVNSVDYLLKPI
                     DADDIRKALDKLSRLQSTTVEKEAIDYSAVMQALKRVEGYKTHFLIPMKGDKLLPVSV
                     DMILFFYIADGNVKAVMTDGKEYLFTQTLDELADSLDPALFFRINRQYLISRKAVQDI
                     DLWFNGRLAVNLIVPTLERILVSKARVPDFKTWFTS"
     gene            complement(2265..3326)
                     /locus_tag="ACZPB4_14075"
     CDS             complement(2265..3326)
                     /locus_tag="ACZPB4_14075"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1099378.1"
                     /translation="MTIFVFMKKMNIKNKYVFSLVIISIMVAFLIHFPELVSLFDVTG
                     QNALFPDMSVLDVANEVFFTFVSLLLLFAMNTYVFGFNRQKARISWQKVLLSFVMTWC
                     VNNLLGKGFVFLHHQFDIPAIDALVHHYLHPLRDFIMSCVVTGSCYMIYLIRQSQQVQ
                     VENQQLRAENLLNQYEALKSQLNPHMLFNSLNTLRSLIRETPGKAQEYLQELSRVLRY
                     TLQENECRSVTLREEMDFVNAYIFLLKMRYEDNLVFDIDLGKEHESKQLPPMSVQLLI
                     ENAVKHNEISNRHSLTISVRSDHDSLTVSNPIQPKLTHSGGTGIGLVNLSKRYNLLYK
                     KDISIKEDASIFSVTIPLV"
     gene            complement(3323..4249)
                     /locus_tag="ACZPB4_14080"
     CDS             complement(3323..4249)
                     /locus_tag="ACZPB4_14080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HIR1099379.1"
                     /translation="MKKIWIPAALMALAACSMTNNAEKGQGDSQDITARPAITQVAEN
                     VPSEPSVDSVEVDGISSATALPNHSSFNGIMVVPPQRQATVTLTMGGTVHATTLLPGD
                     YVKKGSVVVSLENPDFITLQQTYLDAHAQTEYLEAEYKRQQRLSEQEAASQKRFQQSK
                     ADYLSMKSRQDAAAAQLAILGVSAGDLLEDGIQPYLEVKAPLSGYVAGLSINLGKYVN
                     AGEPICDVIDKGETLLCLTAYEKDLADLSIGNQVQFRVNGMGKETFHAVLVSIGQEVD
                     ETSRSLEMYARVKETNPRFRPGMYVSARVEKK"
     gene            complement(4268..8578)
                     /locus_tag="ACZPB4_14085"
     CDS             complement(4268..8578)
                     /locus_tag="ACZPB4_14085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CusA/CzcA family heavy metal efflux RND
                     transporter"
                     /protein_id="HIR1099380.1"
                     /translation="MFKAIVHFSIQKKLFVGLTTLFLLLGGIYAMMTLPIDAVPDITN
                     NQVQIVTVSPTLAPQEVEQLITMPIEIAMSNIMNVEEIRSVSRFGLSLVTVVFKESVP
                     TLDARQLINEQIQTVAGEIPTELGTPELMPITTGLGEIYQYVLSVEPGYEEKYDAMEL
                     RTIQDWIVKRQLSGIPGIVEINSFGGYLKQYEVAVDPDALYSLNITIGEVFEALNRNN
                     QNTGGSYIEKINKAYYIRSEGMIGKIKDIERIVITNRGGIPIHISDVGSVRFGSAKRF
                     GAMTKDGEGECVGGIAMMLKGANANVVTKELEARVERVQKMLPEGVRVEPYLNRSELV
                     DRNISTVIRNLIEGALIVFIVLIIFLGNVRAGLIVASVIPLAMLFAFILMRVFGVSAN
                     LMSLGAIDFGIVVDGSIVILEGMLAHIYSRRLMGRTLSAEEMDREVEAGAGHVARSAT
                     FAVLIILIVFFPLLTLTGIEGKYFTPMAKTLVFCIIGALILSLTYVPMMASLFLKRTI
                     SSKPTFADRFFGKLNGVYRRTLHFCLRHIWGTIACSFAALAVSLFLFTRLGAEFIPTL
                     DEGDFAMQMTLPAGSSLTHSIELSKQAEETLMKSFPEIKHVVAKIGTAEVPTDPMAVE
                     DADIMIVMKPFKEWTSASSRAEMVEKMKASLEPITGAEFNFSQPIQLRFNELMTGAKA
                     DIAIKLYGEDMAELYKKAKEASLFVEQVPGAADVIVEQAMGLPQLVVHYDRAKIARYG
                     MNIEELNTIIRTAYAGEAAGVVFENERRFDLVLRLDNDKVADLNLDKLFVRTAEGIQI
                     PVSEVATIELVNGPLQINRDATKRRIVIGVNVRDADIQKVVRTIQETLDKHIKLEPGY
                     YFEYGGQFENLRNAIDTLTIVIPVALSLILLLLFFAFKSVTYSLVVFSTVPLSLIGGI
                     LALWLRGLPFSISAGVGFIALFGVAVLNGILMINHFNNLRKQTKYQMTTNRILAKGCP
                     HLLRPVFLTGLVASLGFVPMAIAKSAGAEVQRPLATVVIGGLIVSTILTLIIIPVFYR
                     LVNSSAAWKRQRWLKRLLPFLLFLGILFPTHAQQTVSLEEAVTIALENHPRLKTATAS
                     IERSRASRGESWEVSPTTFNYSWGQINGETRNDNQMEITQSLGSLLTPFYKNALVNRQ
                     VATGEYYRDLVKKEITAEVKRAWAYYQYAFHLCALYKEQIEWAGRLRKASQLRYEQGD
                     ITLLERNMSSTLVADLQTRLSQAEEELQLAARRFSWTCYSDSPLLPMDTTLVLFPARV
                     AEIAPSDIHLNYFRSVADEKKAMLRIERSRFFPELSVGYVRQKIAPLSGLDSWMVGIS
                     FPVLFFPQHSRVRQAKIDSYIARTEAESNIRQLNNKVEELSVALRKEGENIRYYTTGA
                     LPEADALLKSATVQFKESETDITQFVQSLNAAREIRRGYIEAVYAYNISALELELYSR
                     "
     gene            complement(8793..9686)
                     /gene="dapA"
                     /locus_tag="ACZPB4_14090"
     CDS             complement(8793..9686)
                     /gene="dapA"
                     /locus_tag="ACZPB4_14090"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007753443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HIR1099381.1"
                     /translation="MADINLKGMGVALITPFKEDESVDYEALGKLVDYQVQNGTDYLV
                     VLGTTAETPTLTEEEKKNIISLVVTRVRGRIPIVLGVGGNCTRSVVEKLKTDNFEGID
                     AILSVVPYYNKPSQEGIYQHYKAIANATHLPIVLYNVPGRTGVNMTAETTLRIAREFD
                     NVIAVKEASGNITQMDDIIKNKPARFNVISGDDGITFPLMTLGAVGVISVIGNAFPRE
                     FSRMVRLALAGDYDSARTIHHSFTELFSLLFVDGNPAGAKSMLNMMGFIENKLRLPLV
                     PTRIVTYEKIREVLRQLSIKC"
     gene            complement(9739..10260)
                     /locus_tag="ACZPB4_14095"
     CDS             complement(9739..10260)
                     /locus_tag="ACZPB4_14095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6913 domain-containing protein"
                     /protein_id="HIR1099382.1"
                     /translation="MFTNYFIKKKIQALVSDAAKRPHRSLSLDEARSLLVLYNIEDHE
                     DVMRALEPLRKAKKDIKTCVYVPSGGADIPFDDSNIPVHSKSDLNAWGFPSDSVLEKV
                     GALKADILIDITRPGCYALQYIALRHPSAFKVGIKYPGQEWYDLGLTVTDKDDIQYLF
                     GQILFYLRSIRAK"
     gene            complement(10261..>12198)
                     /gene="ligA"
                     /locus_tag="ACZPB4_14100"
     CDS             complement(10261..>12198)
                     /gene="ligA"
                     /locus_tag="ACZPB4_14100"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HIR1099383.1"
                     /translation="YYVLSAPTISDFEFDKMMKELQELEAAHPEFADPDSPTRRVGSD
                     LSKEFEQVVHKYPMLSLGNTYSEDEIRDFYDRTVRSLNEPFEIVAELKYDGTSISLTY
                     EKGRLTRAVTRGDGTRGDDVTANIKTIRSVPLRLRGSDFPEEFEIRGEVLLPWAEFDR
                     LNKEREEQEEPLFANPRNAASGTLKQQNPAIVASRKLDAYFYYLLGENLPAEGHYENL
                     QAARAWGFKIPDVIRKCQSLQDIFDYIAYWDVERKNLPVATDGIVLKVNSLRQQRNLG
                     FTSKSPRWAIAYKFQAERAETRLNSVSFQVGRTGTVTPVANLEPVLLAGTVVKRASLH
                     NADIIEGLDLHIGDQVYVEKGGEIIPKIVGVNVEARSMLMGDKVRFIRVCPECGTPLV
                     RPEGEAAHYCPNESGCPPQIKGRIEHFVTRKAMNINIGPETVEDLYNAGYVKDSADLY
                     TLTVADLLRLERWAEKSAQNLMSSLEESKQVPFERVLFGLGIRFVGETVAKRLVSAFH
                     SIEALEQASLEDLVAVDEIGERIAQSVLSYFSDEKNRTLVNRLKEQGLRMAVSEEQLA
                     NRSEKLKGLTIVISGTFSKHSRDEYKAMIEQHGGKNSGSVSGKTDYILAGENMGPAKL
                     EKAAKLGVKIINEDAFLNMLE"
BASE COUNT         3288 a         3330 c         2629 g         2951 t
ORIGIN      
        1 gcttatcggg aaggtctcga tttattacag aaacgaggtg acaatccgaa attcgagatg
       61 caatacatgg gaaacctcat cgaatcttat cttcgaaccg atcatttcac cgaggccgag
      121 gaattattaa cccgttacga tgaaatgatc caagataggg aaagagagaa tgaagaacaa
      181 ggcaccgcat tccccgtgga tcgttgccgt gcgctaatgt atgtttttta tgcggatatg
      241 tatgtccttc aagacaagcc caaggagaca ttggacgcct tgttgaaagc gacaccgatc
      301 gtagagaaaa ccggagatga ttatacggaa ttctgctaca acttcgtttt cgccaagtat
      361 tactatttaa taggtatgta tgaaagggcg ctgaatatca tagataaaaa taaattaaca
      421 gaagaagata tacgaacctc ggagctgaaa gtcgagatac tcgaagcatt gggacgttat
      481 aaagaagcgc tcgcatttag tagagaagtt gtagaacata ccaagatgtt gcatgacgag
      541 gccttcaacc ggcagatcaa tcagctccgg acattacatg atctaaacaa tcaagagatg
      601 caggcatatg aactacagct acgtgaacaa caactgcata cccaaaggtt gttaatgatt
      661 attctactcg tagtatcgat cgtgctttta gtgatgctat acatcgtata caagtcctat
      721 cgctccgcac gccgctacca acgagaactt atgaaagaca aggaagcctt agtagagtcc
      781 gagcgtcaac ttcgtacagc caaagagata gcggaacacg ccaaccagat gaaaagcacg
      841 tttatcgcca atatcagcca tgagatccgt acgccactta acgcgattgt cggcttttcg
      901 gaattaatat ccgatgaatc tatttccgct ggcgaaaaga aagagttttt ctccattatc
      961 aacaataact cttatttatt acttaatctg ataaatgaca ttcttgacct ttctcgccta
     1021 gaatccggga atatgaagtt cattatagag aagacaagct tatcggattg ttgccggaac
     1081 gctttggcaa gtgtagagca ccgggtcttt ccgggtgttc aattgaccta tacaccttct
     1141 gaagacccct tacatatcca gacagattcg atacgtctcc aacaattatt gataaactta
     1201 ttgaccaatg cctgcaagtt cacgaaagaa ggagagatca acctatctta tcaaatagat
     1261 gaggacaagc agcatgtacg tatcaccgta accgataccg gatgtggaat accggaggat
     1321 aagcagaaag tcatattcga gcgtttcgaa aaggtagatg aatacgcgca gggtacaggc
     1381 ttagggttat ccatcagcca aacaattatc gagcatttag gtggctccat tcaattagac
     1441 ccgacgtata agcatggagc ccggttcatc gtactccatc cctacaaccc tcttgataat
     1501 ccatcatgac gtaaaccacg tcttgaaatc cggcactctc gccttgctaa ccaatatacg
     1561 ctccaaggtc ggtacgatca aattgaccgc aaggcgtccg ttaaaccaga gatcgatatc
     1621 ttgcaccgcc tttctggata tcaagtactg acgattgatc cggaagaaca aggcgggatc
     1681 aaggctatcg gcgagctcat ccaaggtctg cgtgaaaagg tattctttcc cgtccgtcat
     1741 caccgccttt acatttccgt ccgctatata gaaaaataag atcatatcca cggaaacagg
     1801 tagcagctta tcccctttca tagggatcaa gaaatgcgtt ttatatcctt ccacccgctt
     1861 caaggcttgc atgacagcgg aataatcgat cgcttctttc tccacagtcg tcgattgtaa
     1921 ccgtgacagc ttatccaaag ctttccgtat atcatccgcg tcgatcggtt tcaacagata
     1981 atctacgcta ttcactttaa acgctttcag cgcatattca tcataggctg tcgtgaaaat
     2041 gatcgggcaa gagatatcta catgaccgaa gatctcgaaa gccgaaccat ccgccaaatg
     2101 gatatccaga aagataagtt ccggcattgg atgcgattga aaccattcaa cactatccgt
     2161 aatactatct aggacatcga tcacctcgat atccggatca gcctctccca gcaatgccat
     2221 caaattacgg acagccgctt tctcgtcttc tattatcaaa gctttcatac caaagggatt
     2281 gttacgctga atatactagc atcttctttt atggaaatat ctttcttata caagaggtta
     2341 taacgtttac tcaggttcac caagccaata ccggtgcctc cgctatgtgt caatttcggt
     2401 tggatgggat tgctaaccgt caaggaatca tggtccgaac gaacggatat ggtcaatgaa
     2461 tggcggttgc taatctcgtt atgcttcacg gcgttctcga tcaaaagctg caccgacata
     2521 ggaggcagtt gcttagactc gtgctccttc cctaagtcta tatcgaaaac tagattatcc
     2581 tcatagcgca ttttcaaaag gaagatataa gcgttcacga aatccatctc ctcccgtaaa
     2641 gtaacactac ggcactcatt ctcttgcaag gtataacgta agacacggga taactcctgc
     2701 aaatattctt gtgccttccc gggagtctcc cggatcaagg aacggagcgt attcaaggaa
     2761 ttaaataaca tatgaggatt aagctggctc ttcaaggcct catattggtt caataaattc
     2821 tccgcccgca attgctggtt ctcgacctgt acttgctggc tttgacgaat caggtaaatc
     2881 atatagcaac tacccgtaac gacgcacgac atgataaaat ccctcaacgg atgcagataa
     2941 tgatgcacca aggcgtcgat cgccgggata tcaaactgat ggtgcaagaa cacgaaaccc
     3001 tttcctaata aattattcac gcaccaagtc attacgaacg agagcagaac cttctgccaa
     3061 gagatacgcg ctttctgccg attgaaacca aagacatacg tgttcatcgc aaataacagt
     3121 aagagggaca cgaaggtgaa aaagacctca ttcgctacat ccaataccga catatccgga
     3181 aaaagagcgt tctgcccggt aacgtcaaac aacgacacca attccgggaa atggatcaag
     3241 aaggccacca tgatcgatat gatgaccaac gagaacacat atttattctt tatattcatt
     3301 ttcttcatga agacaaagat agtcatttct tctctacccg tgcggaaaca tacataccgg
     3361 gacgaaaacg gggattcgtc tctttcaccc gagcgtacat ttccaaggaa cggctcgtct
     3421 cgtccacctc ctgtccgatc gagaccaaga ccgcatggaa ggtctccttc cccattccat
     3481 tcacccggaa ctgcacttgg ttcccaatgg ataagtccgc taaatccttc tcataagcgg
     3541 tcaggcaaag aagagtctcg cctttatcga tcacatcaca gatcggttcg cccgcgttca
     3601 cgtatttacc gagattaatg gacagcccgg cgacataacc gcttaatggc gcttttacct
     3661 ccaaataagg ttggataccg tcttccagaa gatcgccggc ggagacacct aggatagcaa
     3721 gttgcgcagc ggcggcatct tgacggctct tcatggaaag ataatccgcc ttgctttgct
     3781 ggaaacgttt ttgcgaggcc gcttcttgct cgctcaaacg ctgttgcctt ttatactcag
     3841 cctctaagta ttccgtttgg gcatgggcat ccaaataggt ctgttgcaac gtgataaaat
     3901 ccggattctc caagctgacg accacggagc ccttcttcac ataatcgccc ggaagcagcg
     3961 tagtagcatg aaccgtgcct cccatcgtca atgtaaccgt agcctgccgc tgcgggggaa
     4021 ctaccatgat cccgttgaaa gaggagtgat tcggaagggc cgtagccgag gaaatcccat
     4081 ccacctctac gctatccacg gatggttcgg acggtacgtt ttctgctact tgagtaatag
     4141 cgggccgggc agttatgtct tgcgaatcgc cctgtccttt ctccgcattg tttgtcatac
     4201 tgcatgcggc caatgccata agagccgcag gaatccatat ctttttcatc ttatactatt
     4261 tttctggtta tctactatac aactccaact caagcgccga tatattatag gcatatacgg
     4321 cctcgatata tccccgccgg atctcccggg cggcgttcag gctttggaca aactgcgtga
     4381 tatctgtctc gctctctttg aactgtaccg tcgcgctctt caacaaagca tccgcttccg
     4441 gtaaagcgcc ggtcgtataa tagcggatat tctctccttc cttacgaagc gcgacgctca
     4501 actcctccac cttattgttc aattgacgga tgttactctc cgcttccgtg cgggcgatat
     4561 aggaatcgat cttcgcttgc cttacccggc tatgctgcgg gaagaacaat accgggaacg
     4621 agatcccgac catccaagag tccagaccgc tcaacggggc tattttctga cgcacatatc
     4681 ctaccgatag ttccgggaag aaacggcttc gttcgatacg aagcatggct ttcttctcat
     4741 cggccacgct ccggaagtaa ttcagatgga tatcggacgg agcgatctcg gctacgcgag
     4801 cggggaataa aaccaatgtc gtatccatag gcagcaatgg ggaatccgaa taacaagtcc
     4861 aagagaaacg acgggcagcc aattgcaact cctcctccgc ctgcgacaaa cgggtttgca
     4921 gatcggcgac caaggtagat gacatattcc gctccaatag cgtgatatcc ccttgctcat
     4981 aacgcaactg acttgccttt cgcaaacgtc cggcccactc gatctgctct ttatacaagg
     5041 cacatagatg aaaggcatat tgataataag cccatgcccg ttttacctcg gccgtaatct
     5101 ccttcttcac caagtcccgg taatattctc ccgtggcgac ttgacggttc accaaggcgt
     5161 tcttataaaa tggggtcaat agagagccta aggattgcgt gatctccatc tgattgtcgt
     5221 ttcgtgtctc accgttgatc tgtccccatg aataattaaa ggtggtcggt gacacctccc
     5281 agctctctcc ccgtgaagca cgactacgtt caatggatgc cgtggcagtc ttcaggcgag
     5341 gatgattctc caaggcgatc gtcacggctt cttccaacga caccgtctgt tgggcatgcg
     5401 tggggaataa gatacctaaa aaaagaagaa acggcaatag gcgcttcaac cagcgttggc
     5461 gcttccaagc ggccgagcta tttaccaacc gataaaatac cgggataata atcaacgtca
     5521 agatcgtgga gacaatcaag cctccgatca cgaccgtcgc taacggacgt tgcacctccg
     5581 cgcccgcgga cttcgctatc gccatcggca cgaatcctag agaagctacc aagccggtca
     5641 agaatacggg gcgaagtaga tgcggacatc ctttcgcgag gatacgattc gttgtcattt
     5701 gatatttagt ttgtttccgt aagttattaa aatgattaat cattaatata ccattcaaga
     5761 ccgctacgcc aaacaaggcg ataaagccga cccccgccga tatactgaaa ggcaaccctc
     5821 gtaaccaaag ggccagaata ccccctatca aggataacgg gacggtagaa aataccacca
     5881 gcgagtaggt aacactctta aaggcaaaga acaacagcaa taagatcaat gacaaggcga
     5941 ccggtatcac gatcgtaagc gtatcgatcg cattccgcaa gttctcgaac tggccgccat
     6001 actcaaagta gtatcccggt tccagcttga tatgcttgtc aagggtttct tggatagtac
     6061 gcacgacttt ctggatatca gcgtcacgga cattcacccc gatcacgata cggcgtttcg
     6121 tggcatcccg gttaatctgt agaggcccgt tgaccagctc gatcgtagcg acctcgctaa
     6181 ccgggatctg gattccctcg gcagtccgta caaagagctt atccaaattc agatccgcca
     6241 ctttatcatt atccagacga agcaccaagt cgaaacgtcg ctcattctcg aaaacgacac
     6301 ccgccgcctc tcccgcataa gccgtacgga tgatcgtgtt caactcctct atattcatcc
     6361 cgtaacgggc gatcttggca cggtcgtagt gtacgaccaa ttgcggcagc cccatcgcct
     6421 gctccacgat cacatcggcg gctcccggta cttgctccac gaaaagagaa gcttccttcg
     6481 ccttcttata aagctccgcc atatcctctc catatagctt gatcgcgata tccgccttgg
     6541 ctcccgtcat caattcattg aagcgaagct ggatcggctg gctgaagtta aactccgccc
     6601 ccgtaatcgg ttccaaggaa gccttcatct tctccaccat ctccgcacgg ctggaggccg
     6661 aggtccattc cttgaaaggt ttcatcacga tcatgatatc tgcgtcttcc accgccatcg
     6721 ggtcggtcgg aacctcggcc gttccgatct tggctaccac gtgtttgatc tccgggaaac
     6781 tcttcatcaa ggtctcttcc gcttgcttcg atagctcgat actatgcgtc agggaactac
     6841 cggcgggaag cgtcatctgc atggcgaaat ccccctcatc cagcgtaggg ataaactccg
     6901 cccctaacct cgtgaataag aaaagggaca cagccagagc cgcgaaagaa caagcgatcg
     6961 ttccccagat atgacgcaga cagaaatgaa gcgtacgcct gtaaacccca tttaatttcc
     7021 cgaagaaacg atcggcgaat gtaggcttcg aagagatcgt acgctttagg aacagggagg
     7081 ccatcatcgg cacgtaggtg agcgaaagga tcaaagctcc gataatacaa aataccaagg
     7141 tcttcgccat gggggtaaaa tacttgccct ctatcccggt cagcgtaagt agcgggaaga
     7201 agacgatcaa aatgatcaat acggcaaagg tagcgctccg ggcgacatga ccggctccgg
     7261 cctcgacctc ccggtccatc tcctcggcag agagcgtacg ccccatcaac cgcctcgaat
     7321 agatatgcgc caacatcccc tccaatataa cgatcgatcc atcgaccacg ataccgaaat
     7381 cgatggcccc caaactcatc aggttggcgg agaccccgaa aacacgcatc aagataaaag
     7441 cgaaaagcat cgccaacggg atcacggaag ccacgatcaa accggcccgc acattcccca
     7501 agaagatgat caatacgata aagacgatca acgctccctc tatcaagtta cggatcacgg
     7561 tggatatatt tcggtctacc aattcggaac gattcaaata aggttctaca cgaacacctt
     7621 ccggcaacat tttctgtacc ctttcgaccc gtgcctccag ttccttggtc acgacattgg
     7681 cgttcgcacc cttcaacatc atggcgatac cgcccacgca ctctccctcg ccatcctttg
     7741 tcatggctcc aaaacgcttg gcggaaccaa agcgaaccga gccgacatcg cttatatgaa
     7801 tcggtatccc tccacggttc gtgatcacga tgcgctcgat gtcctttatc ttgccgatca
     7861 ttccctcgct acggatgtag taagccttat tgattttctc gatataactg ccgcccgtat
     7921 tctggttatt ccggttgagc gcctcgaaca cctcgccgat cgtaatattc aaggaataaa
     7981 gggcatccgg atctaccgcc acctcatact gtttcagata gccgccaaag ctattgatct
     8041 ccacgatacc cggtataccg ctcagttgcc gtttcacgat ccagtcctga atggtacgga
     8101 gttccatggc gtcgtatttc tcctcataac cgggctccac gctcaataca tattgataaa
     8161 tctcgcccaa gccggtcgtg ataggcatca gctccggcgt acccagttcc gtggggattt
     8221 ctcccgccac ggtctgtatc tgctcgttta taagttggcg ggcatccaag gtaggcacgc
     8281 tttccttaaa cacgaccgtt accaatgaca ggccaaagcg ggaaacggag cggatctctt
     8341 ccacgttcat gatattactc atcgctatct cgataggcat ggtgatcaat tgctctacct
     8401 cttgcggggc caaggttggc gataccgtca cgatttgcac ttgattgttc gttatatccg
     8461 gtacggcatc tatcggtaaa gtcatcatgg catagattcc ccccagaagc agaaacaagg
     8521 ttgtcaaccc aacgaatagt ttcttctgaa tagaaaaatg gacaatcgct ttaaacatca
     8581 cttcatttat ttaatataat agttacaaaa ataaaaggta agcgtttgtc tgccccgtat
     8641 aaaataatga agtgaccgaa atcaaggttg aagtatcggt atgaggagtt ggagcatatc
     8701 aatagaaaaa ggcttcacat gccctctatg acacatgaag ccccttttgt tatcctatat
     8761 aaataataag aatcgttgcc gttaaaagcg gatcagcact taatgctcaa ctgtcgcaac
     8821 acctcacgga tcttctcata cgtgacgata cgtgtaggaa ccaaaggcaa acgaagctta
     8881 ttctcgataa agcccatcat atttaacata ctcttcgctc cggcaggatt tccatccacg
     8941 aacaacaggc tgaacagctc cgtgaagctg tgatggatcg tacgtgcgct atcataatca
     9001 cccgccaagg ccagacgtac catacggcta aactcacgag ggaaggcgtt accgatcacg
     9061 gagatcactc ccaccgcacc taatgtcatt aaagggaaag taataccatc gtcaccggag
     9121 atcacgttga aacgggccgg cttgttcttg atgatatcat ccatctgggt gatattgccg
     9181 gaagcctctt tcacggcgat cacgttatcg aactcacggg cgatgcgaag cgtagtctca
     9241 gccgtcatgt tcacgcccgt acgccccggt acgttataga gtacgatcgg taaatgggta
     9301 gcgttggcga tcgccttgta atgctggtaa atcccttctt gggaaggctt attataataa
     9361 ggtacgaccg agaggatagc gtcgataccc tcaaaattat ctgtcttcaa cttctcgaca
     9421 accgaccgtg tacaattacc tcccacgcct aatacgatag ggatacggcc ccgtacacga
     9481 gtcactacca agcttataat gtttttcttt tcttcttccg taagtgtagg ggtttccgct
     9541 gtagttccca gcactaccaa ataatccgta ccgttctgca cctgataatc caccagcttg
     9601 cctaacgcct cgtaatctac actctcatct tccttgaatg gcgtgatcaa cgccacaccc
     9661 attcctttta aatttatgtc tgccatgggg aaaatattcc tttttgttat ttagcactgc
     9721 aaaaataagg aaattatatc atttagcacg gatggaacgc aaataaaata atatctgtcc
     9781 gaataaatac tgaatatcgt ccttatctgt tacagtcaag cctaagtcgt accattcttg
     9841 gcccggatac ttaatcccga ccttgaaggc ggatggatgc cggagagcga tgtattgcaa
     9901 ggcataacaa cccggccggg tgatatcgat caagatatcc gccttgagag cgcccacctt
     9961 ttccaagaca ctatctgaag ggaatcccca cgcgttgaga tcgctctttg aatgtacagg
    10021 aatattggaa tcgtcgaaag gaatatccgc tcctccggac ggcacataca cacacgtctt
    10081 gatatccttc ttcgccttgc gcaaaggctc caaggccctc atgacgtcct cgtgatcctc
    10141 tatattatac aagaccaaaa gcgaacgtgc ctcatccaag gaaagggaac gatgtggacg
    10201 cttggcagcg tccgacacta aagcctgtat cttcttcttg ataaaataat tcgtaaacat
    10261 ttattccagc atatttaaga acgcatcctc gttgataatc ttcacaccca gcttcgccgc
    10321 tttctccagc ttggccggtc ccatattctc gccggcaagg atataatcgg tcttccctga
    10381 gacggagccg ctattcttgc cgccatgttg ctcaatcatc gccttatact cgtcacgtga
    10441 atgcttggaa aatgtcccgc tgatcacgat cgtcaatcct ttcaacttct cggaacggtt
    10501 cgccaattgc tcctcggaaa ccgccatccg caagccctgt tcctttaatc ggttcaccaa
    10561 cgtacggttc ttctcgtccg agaaataact caatacactt tgggcgatcc gctcgccgat
    10621 ctcgtccacg gctaccaaat cctctaaaga cgcctgctcc aatgcctcga tcgagtggaa
    10681 agccgagacc aagcgtttag cgaccgtctc tcccacgaaa cgaatcccca gaccgaacaa
    10741 gaccctctca aaaggaactt gcttggattc ctccagactc gacatcagat tctgggcgct
    10801 cttctccgcc caccgttcca gacgcaataa atcggcaacc gtcaacgtat ataagtccgc
    10861 cgagtctttt acataaccgg cgttgtacaa atcctccacc gtttccgggc ctatattgat
    10921 attcatcgcc ttccgggtca cgaaatgctc tatacgcccc ttgatctgag gaggacagcc
    10981 cgactcgttc ggacagtaat gtgccgcctc tccctccgga cgcaccaaag gagtcccgca
    11041 ctccggacac acacggataa agcggacctt atcccccatc agcatcgaac gagcctccac
    11101 gttcactccc acgatcttcg ggatgatctc cccgcctttc tccacataca cttggtcgcc
    11161 gatatgcaag tcaagcccct cgataatatc ggcgttatgc aaggaagccc gcttcaccac
    11221 cgtccccgcc aacaatacgg gctcgaggtt cgccaccgga gtgaccgtcc ccgtccgtcc
    11281 cacttggaaa gagaccgagt tcaagcgagt ctcggcacgc tccgcctgaa acttataagc
    11341 gatcgcccag cgagggcttt tcgacgtaaa acctaagttc ctctgctgac gaagcgagtt
    11401 taccttcaac acgattccat ccgtcgccac gggcaggttc ttacgttcca catcccaata
    11461 tgcgatataa tcgaatatat cctgtaggct ctggcattta cggatcacgt ccggaatctt
    11521 aaaaccccat gcgcgagccg cctgcaaatt ctcataatgc ccttcggccg gcaggttctc
    11581 acccaataaa taatagaaat aagcatccag cttacgggag gccacgatag ccggattctg
    11641 ctgtttcaac gtaccggaag cggcgttgcg aggattggcg aacaagggtt cctcctgctc
    11701 ctcccgctcc ttattcaagc gatcgaactc cgcccaaggc agcaatacct cgccacggat
    11761 ctcgaactcc tccggaaaat cagaaccccg gagtcttaat ggaaccgaac ggatggtctt
    11821 gatattcgcc gtcacgtcat caccacgagt gccgtcgcca cgggtcacgg cacgcgtcaa
    11881 gcgtcctttc tcataggtca aagagataga agtaccatca tatttaagct ccgccacaat
    11941 ctcgaaaggc tcattcaagg agcggaccgt acgatcataa aaatctcgga tctcatcctc
    12001 ggagtacgta ttacccaacg aaagcatcgg atatttatgt accacttgct caaactcttt
    12061 cgagaggtcg ctccccaccc tccgggtcgg ggaatccgga tcggcgaact cgggatgcgc
    12121 cgcctccagt tcctgcaact ctttcatcat cttatcaaac tcaaagtctg atattgtcgg
    12181 tgccgaaagc acataata
//
LOCUS       DBMDTB010000107        12173 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_1590_length_12173_cov_12.517064, whole genome shotgun
            sequence.
ACCESSION   DBMDTB010000107 DBMDTB010000000
VERSION     DBMDTB010000107.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 12173)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 12173)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12173
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1590_length_12173_cov_12.517064"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..999)
                     /locus_tag="ACZPB4_14105"
     CDS             complement(<1..999)
                     /locus_tag="ACZPB4_14105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HIR1099384.1"
                     /translation="MKSKNLTLASLFAGLFMFMNPMGSEACTRAVYLGPDDMVVTGRT
                     MDWKEDPQSNLYLFPRGVQRRGAISDNTIQWTSKYGSVVTAGYDIGTCDGMNEKGLVA
                     NLLFLTESSYFRSDDNRPVMGLSIWTQYVLDNFATVDDAVAELSKEVFRIDDPDLPNG
                     AKSTLHLSISDASGNSAIFEYLNGNLVIHEGRECQVMTNSPTYDKQLTLNDYWQQIGG
                     LVMLPGTNRASDRFVRASFYIHAIPQTSNFREAVAGVFSVMRNVSVPLGITTPDQPNI
                     SSTRWRTVADQKNKVYYFESTLSPDIFWVDFKSLDFKAGTPIKKLTLTNGEIYAGNT"
     gene            1215..2240
                     /locus_tag="ACZPB4_14110"
     CDS             1215..2240
                     /locus_tag="ACZPB4_14110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HIR1099385.1"
                     /translation="MTAKQKMSRRNFIRSSVVMGGAWMVAGSIPVESIAGEVRPEIAK
                     SESSAGVSKVYMLKDITPQNMIRLYDALGRKAKGKVAVKLSTGEPGGHNFLQPTLIKD
                     LVKKVNGTIVECNTAYGGGRADTDSHLKAAADHGFTAIAKVDIMDADGEVALPVQGGK
                     HLKEDFVGSHYLDYDFTVVLSHFKGHAMGGFGGALKNISIGIASSAGKAWIHTAGKTK
                     TDLWNNLPEQDHFLESMAEAAKAVTTHCGENILYISVMNRLSVDCDCDSNPEEPKMAD
                     IGMLASLDPVALDKACVDLVYASPDPGRVHLIERMESRHGIHIVEHAEALGMGSQRYD
                     LVSLDDK"
     gene            2360..2962
                     /locus_tag="ACZPB4_14115"
     CDS             2360..2962
                     /locus_tag="ACZPB4_14115"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008025374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HIR1099386.1"
                     /translation="MFSGIVEEAAQVVALQSDKGNLHLTMKCSFVNELKIDQSVAHNG
                     VCLTVVSMTEDTYTVTAIKETLERSNLGNLKVGDKVNLERSMLMNGRLDGHIVQGHVD
                     QTAVCAEVKEADGSWYYTFEYAFDKEMARQGYMTVEKGSVCVNGVSLTVCNSQQNSFQ
                     VAIIPYTHDNTNFCQIEKGTVVNLEFDIVGKYISKMMQFK"
     gene            3164..4078
                     /locus_tag="ACZPB4_14120"
     CDS             3164..4078
                     /locus_tag="ACZPB4_14120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016266923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaJ C-terminal domain-containing protein"
                     /protein_id="HIR1099387.1"
                     /translation="MAYIDYYKILGVNKDASQDDIKKAYKKLARQYHPDLNPNDPDAH
                     RKFQEINEANEVLSDPEKRKKYDQYGENWKHADEFEAQRKQYGQQGGGFGGGFSNGGG
                     TYWSSSGDDGEFSDFFESMFGSRRGGGGRSNHGFRGQDYTAELHLSLMDAAKTHKQVI
                     TVNGKNLRITVPAGVANGQTIKLKGQGGPGMNGGPAGDLYITFIIPDDSRFKRVGDDL
                     YLTVPLNLYTAVLGGEQIIDTLDSKVKLKVKPGTQNNTKVRLKGKGFPVYKKEGQFGD
                     LIVTYSIEVPTNLTEKQKDLFREIQSLN"
     gene            4092..4409
                     /locus_tag="ACZPB4_14125"
     CDS             4092..4409
                     /locus_tag="ACZPB4_14125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperone modulator CbpM"
                     /protein_id="HIR1099388.1"
                     /translation="MQTDLVIVSEYCQKCHIDPSFIILLEEGGLIDINITDGERYLFS
                     SQLRDLEQYTRMYYDLSINIEGIEAIHHMLDRMRNLQAEIQSLRNRLHLYEPFGFDTI
                     ENF"
     gene            4556..4627
                     /locus_tag="ACZPB4_14130"
     tRNA            4556..4627
                     /locus_tag="ACZPB4_14130"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4588..4590,aa:Met,seq:cat)
     gene            complement(4725..6080)
                     /locus_tag="ACZPB4_14135"
     CDS             complement(4725..6080)
                     /locus_tag="ACZPB4_14135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HIR1099389.1"
                     /translation="MRINTGNRDLTSGAVWKVILRFAFPLLIGNLLQQLYNVTDSVIV
                     GQFLGKESLAAVSASFFIYYFIISLVIGIGSGTSVVISQFFGAKEFDKVQKAFSSFFI
                     FMLVAGVLLSIAGIIFAEPMFRLTNTPEDVIPQAVAYFRIYVGGTFLFVTFNSIISIL
                     RGVGESVRPMLFILLTTILNIALDLLFIVVFKWGIEGAARATVIAQGIGMCVALGYVN
                     NTHPLLSIKKQDLLFDMGLFKEGLRIGLPSSVQQCAISLGLIALLGIVNSFGTDTLTA
                     YGAAGKIDTIIIQAVLTLSGALAAFCGQNIGAGHLDRVRDGVRFAMLVNLLLGLATFT
                     AIYFFGDKMMLAFTKDPEVIRIGKEYLLIMGGFFIVHGGLNVFNGALRGAGDTLFPMA
                     VSITCLWLIRIPLAYWFSSIWGRSGIWWAIGASLCIGLTITYIYYKLGFWKNKGPLRK
                     K"
     gene            complement(6106..7476)
                     /locus_tag="ACZPB4_14140"
     CDS             complement(6106..7476)
                     /locus_tag="ACZPB4_14140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HIR1099390.1"
                     /translation="MPKNKPREEKKPIGERISALLARTIRFVTYDIWRITENEVSGLK
                     EIYINIIKTVILAVRGFQSENLQTKASALTYSTLLSIVPLLAVLLGIAKGFGFQGTVR
                     QELFDYFPGHEMELNKAFEFVESYLAQAQGGVIIGVGLILLFYTVINLISSVEDTFND
                     IWQIQKSRPWYRKISDYLALFLVLPVLMTASSGLSIFMSTLQNSFLGQYLFFTPLVEL
                     FLHIAPYIITTLAFTGLYVSLPNTKVRFVNGLVAGFIAGCAFQLFQFIYISGQIWVSK
                     YNAIYGSFAALPLLLLWLQLSWLICLFGAELSYASQNVKKFSFERDSKSISRRYKDFL
                     TLLIASLIVKRFVKGEKPYTADELSDAYRIPIRITTQILYLLTELNIIIEVNYGNDDR
                     VAYYQPAIDVNKITVSYLLTRMDEYGSENFKIDTSKLFSKEWKALLKTREDMIKANDN
                     ILLKDL"
     gene            complement(7506..7860)
                     /gene="rnpB"
                     /locus_tag="ACZPB4_14145"
     ncRNA           complement(7506..7860)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="ACZPB4_14145"
                     /product="RNase P RNA component class A"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00010"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00010"
     gene            8268..9791
                     /locus_tag="ACZPB4_14150"
     CDS             8268..9791
                     /locus_tag="ACZPB4_14150"
                     /EC_number="3.4.21.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Do family serine endopeptidase"
                     /protein_id="HIR1099391.1"
                     /translation="MKNIWKNVLGVALIAAISSGAAIGTSTYLMNKNQRPAELASGVE
                     NTFKQPYRLTNYGTVAAENIDFTTAAESAIHGVVHIKATANAQASNGDGGQQYMDPFE
                     YFFGFGGRGGFQRPQQQPRVGAGSGVIISTDGYIITNNHVIDGADELEVTLNDNRKFP
                     AKIIGADPTTDIALIKIEATDLPTIPFGDSEKLKVGEWVLAVGNPFNLTSTVTAGIVS
                     AKSRGNIGAGGKDRSKIESFIQTDAAVNPGNSGGALVNTKGELVGINTAIYSETGNFA
                     GYSFAVPISIAGKVANDLKQFGTVQRAVLGVLIQDPQYVPDAEKEKVKVFEGAYVGGF
                     AERSSAKEAGIEKGDVIVAVNGVKIKSSSALQEQISKYRPGDKVELTINRNGSTKKFT
                     VELRNAQGSTKVVKGGDSAEVMGAAFKALNDEQKRKLGVSYGIEVTGLTSGKLKDAGI
                     KKGFIIMIVNNQKISAPEDLEKIVESILQGRTEDQGLFIKGFYPNGRTKYYAIDLAE"
     gene            9931..10791
                     /locus_tag="ACZPB4_14155"
     CDS             9931..10791
                     /locus_tag="ACZPB4_14155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008625412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HIR1099392.1"
                     /translation="MRQLKITKSITNRESASLDKYLQEIGREDLITVEEEVELAQAIK
                     RGDRRALEKLTRANLRFVVSVAKQYQNQGLSLPDLINEGNLGLIKAAEKFDETRGFKF
                     ISYAVWWIRQSILQALAEQSRIVRLPLNQVGSLNKISKAFSKFEQENERRPSPEELAD
                     ELDIPVDKISDTLKVSGRHISVDAPFVEGEDNSLLDVLVNDDAPIADRSLMNESLAKE
                     IDRALATLTERECEIIKMFFGIGCQEMTLEEIGDKFGLTRERVRQIKEKAIRRLRQGT
                     RSKLLKSYLG"
     gene            10900..>12173
                     /locus_tag="ACZPB4_14160"
     CDS             10900..>12173
                     /locus_tag="ACZPB4_14160"
                     /EC_number="3.2.1.163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004559 - alpha-mannosidase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HIR1099393.1"
                     /translation="MTTRRNFLKTGSISLAGLLVGEKVYSAVSTPDNKKSFSTIASKV
                     TGDYASKRPAPEARKFTSKAVEEQLKASKARIKDPKLAWMFENCYPNTLDTTCEFKMV
                     DGKPDTFVITGDIHAMWLRDSSAQVYPFVTLAKKDKDLRQMLVGAINRQTACILIDPY
                     ANGFNEGPTGSEWESDRTEMKKELHERKWEIDSLCYPIRLAYHYWKEIGDTSVFDSKW
                     EQAMEAVYRTFREQQRKDSLGPYRFSRVTDRQGDTLLNDGWGSPVNPVGLIVSSFRPS
                     DDATLFGFLVPSNLFAITSLRQVAEILRVVRNNTDLAGRCEALAGEVEEAVKKYAIVE
                     HPEFGKVYAFEVDGYGGQVFMDDANVPSLLALPFLGCVDVNDPVYQNTRRLVLSPSNP
                     YFFKGKAGEGIGGPHIGFNYIWPMSLIMRATTS"
BASE COUNT         3232 a         2849 c         3136 g         2956 t
ORIGIN      
        1 ggtgtttccg gcgtaaatct cgccgtttgt gagcgttagt ttcttgatag gtgtacctgc
       61 cttgaagtcc aagctcttga aatcgaccca aaagatatcc gggcttaaag tagactcgaa
      121 gtaatatacc ttattcttct ggtcggctac cgtacgccag cgggtagagg agatattcgg
      181 ttgatccggg gtcgtgattc ccagaggtac cgatacgtta cgcattacgc tgaatacccc
      241 ggctaccgct tcccggaaat tacttgtctg cgggatggcg tggatataga aagaggcacg
      301 cacgaaacga tcggaagccc ggttcgtacc cggcaacatg accaagccgc ctatctgttg
      361 ccagtaatcg tttaaggtta gttgcttatc gtatgtaggg gaattcgtca tgacttggca
      421 ttcccgtccc tcgtggataa ccaagttccc gttcaggtat tcgaagatag cgctatttcc
      481 tgaagcgtcc gagatcgaga gatgcaaggt cgatttcgcc ccgttcggga gatccggatc
      541 gtcgatgcgg aagacttcct tgcttaactc ggcaaccgca tcatctaccg tggcgaaatt
      601 atcgagtaca tactgcgtcc agatgctaag ccccataacc gggcggttat cgtccgatcg
      661 gaaataagaa gactcggtga ggaacaatag gttggctaca agtcccttct cgttcatgcc
      721 gtcgcacgta ccgatatcat acccggcggt caccacgctt ccgtatttcg aggtccattg
      781 gatggtatta tcggatatcg ctccccttct ctgtacgccc cgggggaaga gatacaggtt
      841 ggattgcggg tcctctttcc aatccatggt acgtccggtt acgaccatat cgtccggccc
      901 gaggtaaacg gcccttgtac acgcctcgct tcccataggg ttcatgaaca tgaacaagcc
      961 ggcgaaaaga gaggccagtg ttaaattctt tgatttcata agatctatat tattaggata
     1021 atctatttat gaaacaagtg gctttaagga atgttttaga atgatatacg ggatacggag
     1081 ccgtgtgaac aacccccatt tcgtttttag gctttcaaaa ttcgttttgt tcgtaaagga
     1141 gtcttatttt tcaagttttt aaagaacttc gcgtatcgat taaataagaa acatatgaat
     1201 ttaaattcta tatcatgaca gcaaaacaaa aaatgtcacg ccgtaacttc atacggagtt
     1261 cggtcgttat gggtggcgca tggatggtgg caggttctat acctgtagag agtatcgcag
     1321 gcgaagtgag gccggagatt gcgaaaagcg aatcctctgc cggagtttcg aaggtatata
     1381 tgttgaaaga tatcactcct cagaacatga tccgtctcta cgacgccttg ggacggaagg
     1441 ccaaggggaa agtggcggtg aagctctcta ccggagagcc gggaggccat aacttcctgc
     1501 aacctacact tatcaaagac ttggtaaaga aagtaaacgg tacgatcgtg gaatgtaaca
     1561 cggcttacgg aggcggacgc gcggataccg acagccattt gaaagccgcc gccgatcatg
     1621 gcttcacggc catcgctaag gtggatatca tggatgccga cggcgaggtg gctcttccgg
     1681 ttcaaggcgg taaacacctg aaagaggatt tcgtaggctc ccattatctg gattatgatt
     1741 ttacggtcgt cctttcccat ttcaagggac atgccatggg cggtttcggg ggagcgctga
     1801 aaaatatctc tatcggtata gcctcatccg ccggaaaggc ttggatacat acggcgggta
     1861 agacgaaaac cgacttgtgg aacaaccttc ccgaacagga tcatttcttg gaatcaatgg
     1921 ccgaggcggc taaggccgtg actacccatt gtggcgaaaa tatactttat atcagcgtaa
     1981 tgaatcgact ctccgtagat tgcgattgcg attcgaaccc ggaagagccg aaaatggcgg
     2041 atatcggtat gctagcctca ctcgatcccg tggccttgga taaggcttgc gtagatctgg
     2101 tttacgcctc gccggaccct ggccgtgtcc acttgatcga gcgcatggaa tcccgccatg
     2161 gcatccatat cgtcgagcat gcggaggcgt tgggtatggg aagccagcgg tatgatttgg
     2221 tctccttgga cgataaataa tatcgtaaat taaaaacatt taataacttc ctttttatcg
     2281 ggcttattac ctcaaaggcg ttatctttgc ccatgaataa ataacagttt tgggagtaca
     2341 aactaaaaac gatttgatta tgttctcagg tattgtagaa gaagcggctc aggtagtagc
     2401 cctccaatcc gataaaggaa accttcatct gacgatgaag tgctcattcg tgaatgagct
     2461 gaaaatagat cagagcgtgg ctcacaacgg cgtttgcctt acggtggtaa gcatgacgga
     2521 agatacgtat acggttaccg ctatcaagga gaccttggaa cgttcgaacc tcgggaacct
     2581 gaaagtgggc gataaggtga acttggagcg tagcatgttg atgaacggcc gtctggacgg
     2641 gcatatcgta caggggcacg tggaccagac tgccgtttgt gcggaggtga aggaggcgga
     2701 cggcagctgg tactatacgt tcgagtacgc ttttgataag gagatggccc ggcaggggta
     2761 tatgaccgtg gagaaaggct ccgtttgcgt gaacggcgtc agtctgacgg tatgcaactc
     2821 ccagcaaaac agtttccaag tcgctatcat cccttatacg cacgataaca cgaacttttg
     2881 ccagatcgag aaaggtacgg tagtgaacct agagttcgat attgtcggga agtatatcag
     2941 caagatgatg cagtttaaat aaggttcgaa gaatttccta tccataaaag gctttagcgg
     3001 tatctgatga tcccggctag agccttttct atctacggac aatcttaatt ccgtgcgtgt
     3061 acgattaaaa acgttttaag taaattttca ctaaccaaaa ctatccttgg tatgtttatt
     3121 gttatataat tatatgagaa aaatagacta aacatatcag attatggcct atatcgatta
     3181 ttacaagatt ttgggggtga acaaggacgc ttctcaggat gatatcaaga aagcctataa
     3241 gaagttggct cggcaatatc accctgactt gaatccgaac gatcccgacg cccatcgtaa
     3301 gtttcaggag atcaatgagg cgaacgaggt gcttagcgat ccggaaaagc gtaagaaata
     3361 cgaccagtac ggggagaatt ggaaacatgc ggatgagttc gaggctcaac ggaagcagta
     3421 tggccagcaa ggtggcggct ttggcggtgg cttctcgaac ggcggaggta cgtattggtc
     3481 ctcctccggc gatgatggag agttctcgga tttctttgag tctatgtttg gttcccgccg
     3541 gggtggcggt ggccgttcta atcatggatt ccgtggacag gattacacgg ccgaattgca
     3601 cttatccttg atggatgcgg ccaagacaca taagcaggtg atcaccgtga acggcaagaa
     3661 cctgcgtatc acggttcccg ccggcgtagc caacgggcaa accattaagc tgaaaggcca
     3721 aggcgggccg ggcatgaatg gaggacctgc cggtgatttg tacatcacgt tcattattcc
     3781 ggacgacagc cgtttcaaac gggtgggaga cgatctgtac ctgaccgtcc ccttgaacct
     3841 ctatacggcg gtcttgggtg gcgagcagat tatcgatacc ttggatagca aggtgaaact
     3901 gaaagtaaaa ccgggcacgc aaaacaatac gaaagtccgg ttgaaaggta agggattccc
     3961 tgtttacaag aaggaggggc agtttggtga cttgattgtc acgtactcga tcgaggtgcc
     4021 gaccaacttg acggagaaac agaaggattt gttccgggaa atacaaagtc taaattaaaa
     4081 acaggtgtat tatgcaaaca gatttagtta ttgtcagtga atactgccag aaatgccata
     4141 tagacccttc gttcatcatt ttgctggaag agggaggttt gatagacatt aatatcacgg
     4201 atggagagag gtatctcttc tcttcccagc tccgtgatct ggaacaatac acacgtatgt
     4261 attacgactt gtctattaac atcgagggaa tcgaggccat tcatcatatg ctggaccgga
     4321 tgcggaattt gcaggcggag atacaatcgt tgagaaaccg tctgcattta tatgaaccat
     4381 tcggttttga tacgatcgag aatttctagt gtcaaattgc tgcttaacaa ggcttcactg
     4441 cccgatagcg aagggtgtac gcaaacaaat tgaaaatatt tcttgaaaat gtttggaagt
     4501 ttggaatgta atatatacct ttgcactcgc aatcaagaaa tgatagcgac tatatcgcgg
     4561 agtggagcag tggtagctcg ttgggctcat aacccaaagg tcgtaagttc gagtcttgcc
     4621 tccgcaacta aaaagtcctc aagtcattga cttgaggact ttttctctat tcaatcaagc
     4681 gatcgggcga tgcgaccccg atggaaacga ataataagct atgcttattt cttccgtaaa
     4741 ggccctttgt tcttccagaa tcccaattta taatagatat aggtgattgt aagcccgatg
     4801 caaaggctgg cgccgatggc ccaccagata ccgctccgtc cccagataga gctaaaccaa
     4861 taggcgaggg gaatgcgtat cagccaaaga caagtgatgc ttactgccat tgggaacagg
     4921 gtatcgccag ctccccgtaa tgccccgttg aagacgttca agccgccgtg tacgataaag
     4981 aatcctccca tgatcaataa atattccttg ccaatccgga tcacctccgg gtccttggtg
     5041 aaagccagca tcatcttgtc cccgaagaaa tagatggccg tgaaggttgc tagacccagc
     5101 aataggttga caagcatggc gaatcgtacc ccgtcacgta cccggtccaa gtgcccagct
     5161 ccgatgtttt gcccgcagaa agcagctagc gccccagaga gggtcaatac cgcttggatg
     5221 atgatcgtgt cgatctttcc cgctgccccg taagcggtga gcgtatccgt gccgaaactg
     5281 ttcacgatcc ccagtaaggc aatcaatcct agcgagatgg cacattgctg tacgctggag
     5341 ggaagcccga tgcggagccc ttccttgaac agtcccatat cgaacaataa atcctgtttc
     5401 ttgatagaga gcaggggatg ggtgttgttc acgtagccta gggccacgca catgccgatc
     5461 ccttgggcga tcaccgtagc ccgtgccgcc ccttcgatcc cccatttgaa aacgacaatg
     5521 aagagtaaat ccaaggctat attcaaaatc gtggtaagca ggataaacag catggggcgc
     5581 acggactccc cgacaccccg caatatggag ataatgctat tgaaagtgac aaacaagaac
     5641 gtacccccta cataaatcct aaaataagcg accgcctgcg ggatcacgtc ctccggtgtg
     5701 ttcgtcagcc tgaacatcgg ctcggcaaaa ataattcccg ctatggacag caatacccct
     5761 gcgaccaaca tgaagataaa gaaagaggag aaggccttct gcaccttatc gaactccttc
     5821 gccccgaaaa actgtgagat caccaccgac gtaccgctcc cgataccgat caccagcgag
     5881 ataataaagt aatagatgaa gaaggaagcc gataccgccg ccagcgactc tttccccaga
     5941 aactgcccga cgatgacgct gtcggtcacg ttatagagtt gttgcagcag attgccgatc
     6001 agcaaaggga aagcgaaacg caggatcacc ttccataccg ccccactcgt caaatcccta
     6061 tttcctgtat taattctcaa ttctcaattc tcaattttca attccctata ggtctttcag
     6121 caggatattg tcgtttgcct ttatcatatc ctcacgtgtc ttcagcaggg ctttccattc
     6181 cttgctgaaa agcttgctcg tgtcaatctt aaagttctcg gagccatact cgtccatgcg
     6241 ggtcagcagg tagctgaccg tgatcttatt gacatcgatc gccggctggt agtatgccac
     6301 acggtcgtca ttcccgtagt tcacctcgat gatgatgttc aactccgtga gcaggtataa
     6361 gatctgtgtc gttatgcgga tagggatgcg gtaagcgtcg gatagctcgt cggccgtata
     6421 gggtttctcg cctttcacga accgtttgac gatcagcgag gcgatcagca aggtcaagaa
     6481 atccttgtac cggcggctga tacttttgct gtccctctca aagctgaatt tcttcacgtt
     6541 ctgggaggcg tacgacagct ctgcgccaaa caagcaaatc aaccaagaaa gctgcaacca
     6601 aagcaacaac aaaggcagtg cggcaaaact accgtaaata gcgttgtact tgctcaccca
     6661 aatctgccca ctgatataaa taaattggaa caactggaag gcgcaaccag cgataaagcc
     6721 tgccaccaac ccgttcacga accttacttt cgtattcggc agggagacgt acagccccgt
     6781 gaaagccaat gtcgtgataa tataaggcgc tatatgcaag aacagctcta cgagtggcgt
     6841 aaaaaacaag tattgcccca agaacgagtt ctgcaaggta gacatgaaga tggacaaacc
     6901 gctggatgcc gtcatcagca ccggcagcac gaggaataag gccagataat cggatatctt
     6961 ccggtaccac ggacgggatt tctggatctg ccagatgtcg ttgaacgtat cctccacgga
     7021 cgagatcaag ttgatcaccg tataaaacaa taaaatcaaa ccgaccccga tgatcactcc
     7081 cccctgcgcc tgcgccagat agctctccac gaactcgaac gccttgttca gctccatctc
     7141 gtgcccgggg aaataatcga acaactcctg ccgtaccgtc ccttggaaac cgaagccctt
     7201 agctatacct aataatacgg ccagcaaagg tacgatagat aacaaggtgc tgtaggtaag
     7261 cgccgacgcc ttggtttgca ggttctcgct ctggaaaccc cgcacggcga gtatgaccgt
     7321 cttgatgata ttgatataaa tctccttcag cccactaact tcattctcgg taatccgcca
     7381 aatgtcgtag gtaacgaaac ggatggttcg tgctaataat gcgctgatcc gttctccaat
     7441 aggtttcttt tcttcccgtg gcttgttttt gggcatatcg gcacatgatt taattggcaa
     7501 ataaaaaaag cagtctgcct ataagccggg tcctgtacct ctttggaaag aggcgcctgc
     7561 catttatctt gtcttaccgt cgccggtaag ctttagcggt ctaccccccg gcatcggacg
     7621 agccatccta catgcgccgg tatacatgac cttacaaccc ataagacgta cggcatcccg
     7681 tatcgctacg ggacccggtg agctcttacc tcaccttttc acccttaccg gacgagtccg
     7741 gcggttattc tctgttacgt tactctaccc tcacggacag cttcccgtta agaagtatgg
     7801 tgctctgtgt tgcccggact ttcctcacac ccgaaggtga gcgacagacc ggcagactgc
     7861 gataggacaa agataggtat tttagttgac agttgacggt cggcggttga caattatttt
     7921 ggagacgcat cggagagata ggataacatt ttctttttca gccgtaaaca tattctgtct
     7981 cctaggtgtt tttttatacg aacagggact ctagattgcc agtaaccgac tgtcatttat
     8041 caattgtcga ctgtcagtta tcgcatgtca actgtcaatt cgtctgctgt ttaattgtta
     8101 aaaaggtact ttgcaataca cagtactgtt aagtgcggtt aagcctctgt gatgcctcgt
     8161 taaaagtgat aaaaaatacg atggaaatgg aatatccgca caatttttga gttttctttg
     8221 ccgtaaagaa actgttaaat ttaagtgttt aattaaataa gaaaagtatg aaaaatatct
     8281 ggaagaatgt gcttggtgtt gctctgatag cagccattag ttctggtgcc gcgatcggaa
     8341 cgagtactta cctgatgaat aagaatcaac gtccggcgga gttggcctcc ggagttgaga
     8401 ataccttcaa gcaaccgtac cgattgacga attatggaac cgtggccgcc gagaatatcg
     8461 atttcactac ggccgccgag agcgccatcc acggggttgt ccatatcaag gccacggcta
     8521 atgcgcaagc ctctaacggg gacggcggtc agcagtatat ggacccgttc gagtatttct
     8581 tcggcttcgg tggccgtgga gggttccaac gtccgcaaca gcaacctcgt gtgggcgccg
     8641 gctcgggtgt cattatctct acggatggtt atatcatcac gaacaaccac gtgatcgacg
     8701 gagcagatga gctggaggtt accttgaacg ataaccggaa attcccggca aagattatag
     8761 gggctgatcc gacaacagat atcgccttga tcaagatcga ggcaaccgac ttacctacga
     8821 tcccctttgg tgattctgag aagttgaaag taggtgagtg ggtgttggcg gtaggtaacc
     8881 cgtttaactt gacctctacc gttacggcag gtatcgtgag cgctaagagc cgtggtaaca
     8941 tcggcgccgg tggcaaggat cgtagcaaga tcgagtcgtt tatacagaca gacgccgccg
     9001 tgaacccggg taacagtggt ggggcgctag tgaacacgaa aggcgagtta gtcggtatca
     9061 ataccgctat ctactccgag accggtaact tcgccggata ctctttcgcc gtgcctatca
     9121 gcatcgccgg taaggtggct aacgacttga agcaatttgg aaccgtgcag cgtgctgtat
     9181 taggcgtatt gatacaagac ccgcaatacg tgcccgacgc tgagaaagag aaagtgaaag
     9241 tattcgaggg cgcttacgta ggtggtttcg ccgagcgcag ctccgctaag gaagccggaa
     9301 tcgagaaggg tgacgtgatt gtagctgtga acggcgtgaa gatcaaatcg tctagcgctt
     9361 tgcaagagca gatcagcaaa taccgtccgg gcgacaaggt agagttgacg atcaaccgca
     9421 acggtagcac gaagaaattc acggtagaac tccgtaatgc gcaaggtagc accaaggtcg
     9481 tgaagggtgg cgacagcgca gaggttatgg gcgcagcgtt caaggctttg aacgacgagc
     9541 agaaacgtaa gttaggtgta agttatggta tcgaggtcac cggtctgacc agcggcaaac
     9601 tgaaagacgc cggtataaag aaaggcttca ttatcatgat tgtaaacaac cagaagatct
     9661 ctgctccgga agacttggaa aagattgtgg aaagcatact tcaaggacgt acggaagatc
     9721 aaggcctctt cattaaaggc ttctacccga acggacgtac gaagtactat gcgatagatc
     9781 ttgccgaata agataaacaa ggactgtagt cttataggtg tgaaaagatt gttaaaggtt
     9841 tttaattggc tggatgtggg gtgcatccag ccaattcttt caacaaaaat ggttatcttt
     9901 gcaccccgta ttctcaatta aacaaattga atgagacaat taaagatcac aaagtccatt
     9961 accaaccgcg aaagcgcttc gctggataaa tatcttcaag agattggtcg agaagatctt
    10021 atcacggtag aagaggaagt ggaattggca caggctatca aaagaggaga ccgtagggcg
    10081 ttagagaaat tgacccgtgc gaatctccgt ttcgtcgttt ctgtggctaa gcaatatcag
    10141 aaccaaggtt tgagtttgcc cgaccttatt aatgagggta acttaggctt gatcaaggct
    10201 gccgagaaat tcgatgagac gagaggtttc aagtttattt cctatgctgt atggtggatt
    10261 cgccaatcta ttctgcaagc tttggcagag cagtcaagaa tcgtgcgtct tccgttgaac
    10321 caagtaggct cgctgaacaa gatcagcaag gccttctcca agttcgagca ggaaaacgag
    10381 cgcagaccgt ctccagagga acttgctgat gagttggata tcccggtgga taagatttcc
    10441 gataccttga aggtgtccgg acgtcatatt tccgtggatg ccccgttcgt ggaaggcgaa
    10501 gacaacagcc ttttggatgt gcttgtgaac gatgacgctc ctattgcgga ccggtcgtta
    10561 atgaacgagt cattggctaa ggaaattgat agagcgcttg ctacactgac cgaaagagaa
    10621 tgtgagataa tcaagatgtt tttcggtatt ggctgtcagg aaatgacatt ggaagagatt
    10681 ggcgacaaat ttggcctcac tagagagcgt gtccgccaga tcaaggaaaa agcaatcaga
    10741 agattaagac aaggaactcg tagcaagctt ctaaaatcgt atttaggcta atttaaggaa
    10801 ttattgagtt ggcgaaggct ccggtccgaa aaggattggg agcctttatt ttttttctta
    10861 actttgccac tggaatataa taccataaaa actatataaa tgactacaag acgtaatttc
    10921 ctgaaaacag gatctatttc cttggccggc ctgttggttg gcgagaaggt atactccgcc
    10981 gtgagtacgc ccgacaataa aaagagtttt agcacgatcg cctctaaggt gaccggcgat
    11041 tacgccagca agcgcccggc tcccgaggcc cgtaagttta cctccaaggc ggtagaggag
    11101 caactgaagg cttccaaggc ccgtatcaag gacccgaagc tggcttggat gttcgagaac
    11161 tgctacccga ataccttgga cacgacctgt gagttcaaga tggtagacgg caagccggat
    11221 acgttcgtga tcaccggaga tattcacgcc atgtggttgc gtgactcctc ggcgcaggtt
    11281 taccccttcg tcaccttggc gaagaaggat aaggacttgc ggcaaatgct ggtcggagct
    11341 atcaatcgcc agaccgcctg catcctgatc gatccctacg ctaacggctt caacgaaggc
    11401 cctaccggga gcgagtggga gagcgaccgc acggagatga agaaagagct tcacgagcgt
    11461 aaatgggaga tcgactcgct ttgctacccg atccgcttgg cgtatcatta ttggaaagag
    11521 attggcgata cctccgtatt cgacagcaaa tgggagcagg caatggaggc cgtttaccgt
    11581 accttccgtg agcaacagcg caaggatagc ctcgggccgt accgtttctc ccgtgtgacg
    11641 gaccgccaag gcgataccct cttgaacgat ggttggggta gcccagtgaa cccggtgggc
    11701 ctaatcgtct cttctttccg tccttccgac gacgctacgc tgttcggctt cttggtacca
    11761 tcgaacttgt tcgctatcac ctcgcttcgt caggtggctg agattcttcg tgtcgtaaga
    11821 aataacacgg acttggccgg ccgttgcgag gcgttggcgg gtgaggtaga ggaggccgtg
    11881 aagaaatacg ctatcgtgga gcatccggaa ttcggtaagg tatacgcctt cgaggtggat
    11941 ggttatggtg gacaggtatt catggacgac gctaacgtac cgagtttgct ggctttgccg
    12001 ttcttgggtt gcgtggacgt gaacgacccg gtttaccaga atacccgccg cttggtgctg
    12061 agtccttcca atccttactt cttcaaggga aaggccggcg agggcatcgg cggtccgcat
    12121 atcggtttca actatatctg gccgatgagc ttgatcatgc gtgctacgac ttc
//
LOCUS       DBMDTB010000108        12072 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_1606_length_12072_cov_12.352101, whole genome shotgun
            sequence.
ACCESSION   DBMDTB010000108 DBMDTB010000000
VERSION     DBMDTB010000108.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 12072)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 12072)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12072
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1606_length_12072_cov_12.352101"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..357
                     /locus_tag="ACZPB4_14165"
     CDS             <1..357
                     /locus_tag="ACZPB4_14165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY-like domain-containing protein"
                     /protein_id="HIR1099394.1"
                     /translation="PIVIPKEVSNLMEITFANAELLDIQQNSLGYELDMIDNQIYKVA
                     QLNKDYRWQSTTWAMSEQEVPQIVMQGFESSAYASDKVQSIYTLLNANGTFYLFKVSH
                     NGQDETITFDVFGNIV"
     gene            complement(426..2930)
                     /gene="galB"
                     /locus_tag="ACZPB4_14170"
     CDS             complement(426..2930)
                     /gene="galB"
                     /locus_tag="ACZPB4_14170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004565 - beta-galactosidase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase GalB"
                     /protein_id="HIR1099395.1"
                     /translation="MKRTSFAILIGLFCLFPALFSQVRSEFLLEKNWKFTREDSPEFI
                     NPTFNDSKWQSVTVPHDWAIYGPFSSQNDKQEVAIAQDGQTEAMEHAGRTGGLPFVGV
                     GWYRTEFEVPQFTDGKRATILFDGAMSHAKVYVNGQEVGYWPYGYNSFYFDITKQLMP
                     GKKNTLAVRLENLPESSRWYPGAGLYRNVHVIVTENAYIPVWGTYITTPTATKEFAKV
                     NVQTKIVLPEGADASKYSVKTSVWNPNGQKLTEQTTPLSQIKYNDNSLSQEFIIQTPT
                     LWSPDMPALYSAETRLYEGDQLKDIYTTPFGIRSIEIIPNKGFFLNGEKTVFKGVCNH
                     HDLGPLGAAVNDAAIRRQIRILKDMGCNAIRTSHNMPAPELVRACDEMGMMLMAESFD
                     EWNKAKCANGYNLIFDEWVEKDLVNLVHHYRNNPSVVMWCVGNEVPNQWDESGCKISK
                     FLQDICHREDPTRPVTQGMDAPDAVVNNNMAAVMDVAGFNYRPFRYQVNYKKLPQQII
                     LGSETASTVSSRGVYKFPVERKAMAVYEDHQSSSYDVEHCNWSNLPEDDFIQHEDLPY
                     CIGEFVWTGFDYLGEPTPYYTNWPSHSSLFGIIDLAGIPKDRYYLYRSHWNKSAKTLH
                     ILPHWTWPGREGEVTPVFVYTNYPSAELFINGKSQGKRTKDLSIGIDSSYTEAAQKSF
                     ERQKRYRLMWMDTKYEPGTLKVVAYDKEGNAVAEEEVHTAGKPHHIELSADRNQLTAD
                     GKDLSFINVRVVDKNGNLCPDDTRQIQFKVRGAGAYRAAANGNSASLELFHLPEMKLF
                     SGQLTAIVQTAEEPGTIYFEASAPGVKGATLELISK"
     gene            3018..4328
                     /locus_tag="ACZPB4_14175"
     CDS             3018..4328
                     /locus_tag="ACZPB4_14175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic C4-dicarboxylate transporter family
                     protein"
                     /protein_id="HIR1099396.1"
                     /translation="MLLQLAFVLIAIIIGARIGGIGLGVLGGLGLGILTFGFGLQPTS
                     PPIDVMLMIVAVIAAASCMQAAGGLDLMVKWAEKLLRKNPQRITILSPLVTYLFTFIA
                     GTGHVAYSVLPVIAEVATETKIRPERPMAIAVIASQQAITASPISAATVALLSMLSGY
                     NISLMNILMISVPCTLLGVLAGAIYSLKVGKELDQDPEYLKRVANHEFSTEHYEAKGV
                     ENQMKAALSVSIFVLATIAIVIFGSMESLRPVFTVGTEKVSMQMSHIIEVLMLTASAF
                     ILLFTKTDGIKAAQGSVFSAGMQAVVAIFGIAWMGDTFIAGNMTELKGSIEHIVTQMP
                     WLFGLALFVMSILLFSQAATIRALLPLGIALGISPYMLIALFPAVNGYFFIPNYPTVV
                     AAINFDRTGTTRIGKYILNHSFMMPGLIATGVSVGLGLLFIQFI"
     gene            complement(4400..4759)
                     /locus_tag="ACZPB4_14180"
     CDS             complement(4400..4759)
                     /locus_tag="ACZPB4_14180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin domain-containing protein"
                     /protein_id="HIR1099397.1"
                     /translation="MVVIDLTKDGFIANVGDFEANPKDWKYIGSRPCLIDFHAPWCGY
                     CKRLSPILDEFAKEFDGKIYIYKVDVDQEEALETAFNIRTIPTLMFCPLDGPREMMIG
                     TMGKLELKQLIQEKLLK"
     gene            4858..6057
                     /gene="ilvA"
                     /locus_tag="ACZPB4_14185"
     CDS             4858..6057
                     /gene="ilvA"
                     /locus_tag="ACZPB4_14185"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004794 - threonine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006567 - L-threonine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase"
                     /protein_id="HIR1099398.1"
                     /translation="MLTLDKIYQASYALKTVIRRTDLISAPNINPESHIFLKPENLQV
                     TGSFKVRGACFKIAQLTEEEKSHGVVACSAGNHAQGVALAATAHGIKSLICLPDNAPI
                     SKVEATKSYGADVCLVEGVYDDAYNKALQLKDEKGYTFIHPFDDEDVIAGQGTIGLEL
                     LEQLPEVEAVIIPIGGGGLISGVAYAIKNLNPNIRVYGVQAKGAPSMLNSIEHGKIER
                     LEGVRTIADGIAVKEPGIHTFDLCQQYVDEIVSVTDDEISTAILALIEQHKLIAEGAG
                     AVAVAAAMFNKVPIKGKKVICLISGGNIDVNILSRVIGRGLQKSGRSCSMTIELVDKP
                     GQLQHVSEIIASTGANVVSVYHERVSHTADINGCYLRLEMETRNQQQINEIRQLLTVS
                     GYKIVEG"
     gene            complement(6220..6504)
                     /locus_tag="ACZPB4_14190"
     CDS             complement(6220..6504)
                     /locus_tag="ACZPB4_14190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HIR1099399.1"
                     /translation="MFKELDPLLHSQLRLAIMSILLSVEEAEFVYIKEKTNATAGNLS
                     VQLDKLNEAGYIEIEKGFAGKKPRTVCRITDKGRLAMEEYVNTLRQYINI"
     gene            complement(6489..7118)
                     /locus_tag="ACZPB4_14195"
     CDS             complement(6489..7118)
                     /locus_tag="ACZPB4_14195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099400.1"
                     /translation="MEDRKLSEKESLDIITQMINSSKRNMKVGSGNVLLYWGYFTVLL
                     SVVISSLIVYTQNYIWSWGWMLMFAVGPVISYKQRGCEPAVVTYTDKTISSVWQVFGC
                     MFGLTFVLIAAFCVLYEQSVNFILMLPLSLLYCGLGVSINGIILREKWMIYSPVVAFV
                     LVIYMLMSLINHGPVTVLWYLYFGLSFVVMMIIPGHILNNKAKKQCLKN"
     gene            complement(7216..9588)
                     /locus_tag="ACZPB4_14200"
     CDS             complement(7216..9588)
                     /locus_tag="ACZPB4_14200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane beta-barrel protein"
                     /protein_id="HIR1099401.1"
                     /translation="MVRFLLLSLWILAIGGGSAQKISGQTVYKAHVSDAEGNAVEYAT
                     AVLLSGEKQVGGAVANSDGDFSMEAEAGKYRLVVQCLGYEPLRKELILPIKRRDSLIL
                     DLSNRVLREVVVRAKNIERKADRFIMSVMPSAGKDGTELLSQAPGVWLSDGTISINGA
                     QGAKVFVDDREIRLTGEELLAYLRSLKSEDIKRIEVIPIAGVEYEASTKGGVIKISLR
                     QRPDNGMQGYVSLGTSLSPSLQGYIPSASVNARVGKWSLNGAVSGTFTPRDKGEMNSN
                     REYGTVGNKFVSQSLYDTDSKYGNGRVGAIFEIDSLNSVGAEIEYINQASDGTSWSQT
                     DLVKNSYPMKSTGNYRQKDDYNTFSATVNYLRKMDEQGSIFKVIADFVNKRSTGDNLH
                     TIRYEQSNWSRDTVYRSHAAADYDMATTDISFQKNLREKMSLKIGTKYTYTLMDDHSL
                     YEGLNSSGSWIPNEEYGYTLRYNENIVGAYASFSAEIKNWSFVAGVRAEYSKTSDRSE
                     DFSRDYLDLFPNLNVTYAFDPIKRWMLVGQYARNIERPPFYTLNPNRIQSSDYSYQIG
                     NPYLRPTYINRFSVTLVYNYRYTVTVGGNLYHDLIREFCKQDVANPDVSYITYENHDR
                     ENHWFVAVSLPYQPFTWCNLTGNFIGVRQDIRMTELSSFSSHYLGFANAIATFTLPAG
                     FTVEARYSGTSRLYSGNSEVAPRHTVGVMARKKFLNDKLLLAVSVDNIFNQANEYAST
                     LDVYRTSSRYENGLTGRVFKVALTWNFNSGKKVRKSKIEIGSERSRLNEK"
     gene            complement(9593..9964)
                     /locus_tag="ACZPB4_14205"
     CDS             complement(9593..9964)
                     /locus_tag="ACZPB4_14205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2141 domain-containing protein"
                     /protein_id="HIR1099402.1"
                     /translation="MRRVLFILSLFMLVCGCIEARTIIVEIGNIRGNHGNILVMAQSG
                     KDTKPVYGMAKSEKGKVTIRLENVDWEKFDLSVFHDENENWQMDMLEGKGPAEGYALK
                     SCEVKDKEATFKLKLYYPVNQ"
     gene            10299..10826
                     /locus_tag="ACZPB4_14210"
     CDS             10299..10826
                     /locus_tag="ACZPB4_14210"
                     /EC_number="3.1.1.106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetyl-ADP-ribose deacetylase"
                     /protein_id="HIR1099403.1"
                     /translation="MNERIIAIQADITTLDVDAIVNAANNSLLGGGGVDGAIHWAAGP
                     ELLDECRTLQGCPTGEAKITKGYRLKARHVIHTVGPIYRNGQHGEPELLENCYRNSLR
                     LAKENRLRTIAFPSISTGVYGYPIEEAAQIAIRTIDTFLKENPEIQQVTMCCFSGYDK
                     SVYTKALEQITTHEP"
     gene            complement(10807..11466)
                     /locus_tag="ACZPB4_14215"
     CDS             complement(10807..11466)
                     /locus_tag="ACZPB4_14215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5715 family protein"
                     /protein_id="HIR1099404.1"
                     /translation="MKMKTVFNVMLLLVVIVSATAFSSCKEKRGELKKIWYNGSYNRD
                     FNDLNDVHLSVAKKIGIEPVSSREGAEHASRDMVEIKTNDYYEVEELTHSIPYLVPEA
                     ANLLEDIGKNFQDSLKNLNASIYKIKVTSVTRTVADVKKLRKRNTNSSLNSAHQYGTT
                     FDVSWVRYTKIDEKDTLNIDKDRLKMVLASVLRDLRRADRCYIKHERKQGCFHITARE
                     L"
     gene            11693..>12072
                     /locus_tag="ACZPB4_14220"
     CDS             11693..>12072
                     /locus_tag="ACZPB4_14220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HIR1099405.1"
                     /translation="MIERIYILESVDPVIFYGVNNSNMQLIKTLFPKLRIVARGNVMK
                     VIGDEDESELFLKKIREVEKYCEEFNSLSEDVILDIIKGKGPTVVKQENLIIHGMNGK
                     PITARTENQQLLVKAFENNDLVFAT"
BASE COUNT         3352 a         3018 c         2449 g         3253 t
ORIGIN      
        1 ccgatcgtta tcccgaaaga ggtcagcaac ctgatggaga tcactttcgc caacgccgag
       61 ttgctggata tccaacagaa cagcctaggt tacgagctgg atatgatcga taaccagatt
      121 tataaagtgg cgcaattgaa taaggattac aggtggcaaa gtaccacatg ggccatgtcc
      181 gagcaagagg ttccgcagat cgtgatgcaa ggcttcgaat cctccgctta cgctagcgac
      241 aaggtacagt ccatatatac gttattgaat gccaatggca ccttctacct attcaaggtt
      301 tcacataacg ggcaggacga gacgattacc tttgatgtat tcgggaatat cgtataaaaa
      361 agccgcgcga ttcacagccg tctccggact tgaatcgcgc ggtttacgtt atatgataat
      421 caagcttatt tactgatcaa ttccaaggtc gcccctttta ctcccggtgc ggaagcctcg
      481 aaatagatcg tccccggttc ctcggccgtc tgcacgatag cggtaagttg cccgctaaac
      541 agtttcattt ccggaagatg gaagagttcc agactggcgc tatttccatt tgccgccgca
      601 cggtaggctc cggcaccacg taccttaaac tggatctggc gggtatcatc cggacaaagg
      661 ttaccgttct tgtctacgac tctaacattg atgaaagaaa ggtcttttcc gtcagccgtc
      721 aattggttac gatcggcgga taactcaata tgatgcggct tccctgcggt atgaacctcc
      781 tcctcggcca cagcgttacc ctccttatca taagcgacca ctttcaaagt tcccggctcg
      841 tatttggtat ccatccacat caaacgatat cgtttctggc gctcgaaact cttttgagcc
      901 gcttcggtat aactactatc gataccgatg cttaggtctt tcgtacgttt cccttggctc
      961 tttccgttga taaacaattc ggcggaagga taattggtat aaacgaatac gggtgtcacc
     1021 tcgccctcac gtcccggcca tgtccaatgc ggcaggatat gcaaggtctt ggcgcttttg
     1081 ttccaatgac tacggtatag atagtaacga tccttgggga tacccgccaa atcgataata
     1141 ccgaacaagg agctatggct tggccaattc gtataataag gagtaggctc gcccagataa
     1201 tcaaatcctg tccatacgaa ttccccgata caatacggaa ggtcctcatg ctggataaaa
     1261 tcgtcctccg gcagattaga ccagttgcaa tgctccacgt cgtacgagga actttggtga
     1321 tcctcataga cagccatcgc cttacgctct accgggaatt tataaacccc tcgtgagcta
     1381 accgtggagg ccgtctcgct tcccaagatt atttgctgag gcagtttctt ataattcact
     1441 tgataacgga acggacgata attgaatccc gccacatcca tcaccgccgc catattatta
     1501 ttcacgacgg catccggggc atccatacct tgcgtcaccg gacgagtcgg gtcttcccga
     1561 tggcagatat cctgcaagaa cttggagatc ttacaaccgc tctcatccca ttggttaggc
     1621 acctcgttac cgacgcacca catcacgacg ctcgggttat tccggtaatg atgtaccaga
     1681 ttcacgaggt ctttctccac ccattcgtcg aaaatcaaat tatagccgtt cgcgcatttc
     1741 gccttgttcc actcgtcgaa gctctctgcc atcaacatca tacccatctc atcgcaagcc
     1801 cttaccaact cgggagccgg catattatgg gaagtacgga tagcgttgca tcccatgtcc
     1861 ttcaagatcc ggatctgacg acggatagcg gcatcattga cggcagcccc taacgggcct
     1921 aagtcatggt gattacaaac gcctttgaat accgtcttct caccattcaa gaaaaagcct
     1981 ttattcggaa tgatctcgat tgaacggata ccgaacgggg tcgtatatat atctttcagt
     2041 tgatcgccct catagagacg agtctccgcg gaatacaggg cgggcatatc cggcgaccat
     2101 aaagtcgggg tctggatgat aaactcttgg gagaggctat tatcattgta cttaatctgt
     2161 gagagaggcg tagtctgctc cgtcaacttc tgcccgttcg gattccatac actggttttc
     2221 acgctatact tgctggcatc ggcaccttcc ggcagtacga ttttcgtctg tacattgact
     2281 ttcgcaaatt ccttcgtggc ggtcggggtc gtaatataag ttccccagac cgggatatag
     2341 gcgttttccg tcacgattac atgtacattc ctatataatc ccgctcccgg ataccaacgg
     2401 gaggattccg gcaagttctc gaggcgaacc gccaaggtgt tctttttccc cggcatgagt
     2461 tgtttcgtga tatcgaaata gaaagaatta tagccatacg gccaatatcc aacctcttgt
     2521 ccgttcacgt agaccttagc atggctcatc gcaccgtcga acaggatcgt ggcacgcttc
     2581 ccatccgtaa attgaggaac ctcaaactcg gtccggtacc agccgactcc cacgaaaggc
     2641 aaacctccgg ttcggccggc atgttccatg gcctccgttt gtccgtcttg ggcgatagcg
     2701 acctcttgct tatcattctg agagctgaaa gggccgtaaa tcgcccaatc atgcggaacg
     2761 gtcacggatt gccatttgct atcgttaaaa gtaggattga taaactccgg gctgtcttcc
     2821 cgggtgaact tccaattctt ttccaacagg aactcactgc gtacttgaga aaaaagcgca
     2881 gggaaaaggc aaaacaaacc gatcaaaata gcgaaacttg ttcttttcat tcgttttttg
     2941 tgtttttgtt attcatagcg gaacaaaaat aagtattttt gtctccaata caaactaaat
     3001 caaaagaatt gcacagcatg ttgttacaat tagctttcgt tttaatagcc atcattatag
     3061 gtgcccgtat cggtggtatc ggattaggcg tgttaggagg tctcggactc ggtatactca
     3121 cctttggatt cgggctccag cccacttccc ctcctatcga tgtcatgctt atgatcgttg
     3181 ccgtaatagc ggcggctagt tgtatgcaag ccgctggcgg acttgacctt atggttaagt
     3241 gggcggaaaa attgcttcgc aagaatcctc aacgaattac gatattaagc ccgctcgtca
     3301 cctatttgtt taccttcata gccggaacgg ggcatgtggc ttattcggtc cttccggtaa
     3361 tcgccgaggt cgcaacggaa acgaagatcc gtcccgaacg tccgatggcg atcgccgtga
     3421 tcgcttctca gcaagctatt accgctagtc cgatatcggc ggctacggta gctttattaa
     3481 gtatgttgtc cggatacaat atctccttga tgaatatctt gatgatctct gttccttgta
     3541 ccttattagg tgtgttagcg ggagcgatct actctttaaa ggtcggtaaa gagctagatc
     3601 aagatccgga atacttaaag cgggtggcga accatgagtt tagcacggaa cattatgagg
     3661 cgaaaggcgt tgaaaaccaa atgaaagcgg ccttatcggt ctctatattt gttctcgcta
     3721 cgatagcgat cgttattttt ggttctatgg agtccctacg tccggtcttt accgtcggca
     3781 cggaaaaggt ctcgatgcag atgtcacata ttattgaggt attaatgttg acagcctccg
     3841 ctttcatctt attatttaca aaaacagatg gtatcaaggc cgcacagggt tccgtttttt
     3901 ccgcaggtat gcaagcggtg gtagcgatct tcggtatcgc ttggatggga gatacattta
     3961 tcgccggcaa tatgactgaa ttaaagggat ctatcgagca tatagttaca cagatgcctt
     4021 ggttattcgg attggccctt ttcgtaatgt ccattttatt atttagccaa gcggctacca
     4081 ttcgtgcgtt attgccgcta gggatcgcat tgggaatctc accctatatg ttgatcgctt
     4141 tattccccgc cgtaaacggt tatttcttca tcccaaacta cccgacagtc gtagccgcca
     4201 tcaacttcga ccgcacgggc acgacccgca tcggtaaata catcttgaac cattctttca
     4261 tgatgccggg attgatagcg accggagttt ctgtaggatt ggggttacta ttcattcaat
     4321 tcatataata agaaagcaaa aaatagagac gcagcatata cgctacgtct ctacacccca
     4381 caccatatat catattatat tacttcaaca atttttcctg aatcaactgc tttaactcca
     4441 gttttcccat cgtgccgatc atcatctcac gggggccgtc tagcgggcaa aacatcaaag
     4501 tgggaatcgt tcggatatta aaggctgtct cgagtgcctc ctcttgatct acatccacct
     4561 tataaatata aatcttccca tcaaattctt tggcaaactc atccaatatc gggcttaagc
     4621 gtttgcaata accgcaccaa ggagcgtgaa aatctatgag gcaaggacga cttcctatat
     4681 atttccaatc tttgggattc gcctcaaaat caccgacatt ggcgataaaa ccatctttcg
     4741 ttaaatcgat cactaccata cttctctata ttttgattta taatataaca aagataagta
     4801 tgaataggtt gcggtatttt ttatactttc gcgacatcgt tttaacatac agacagaatg
     4861 ctcacacttg ataaaattta tcaggcatca tatgccttga agacagtcat cagacgcact
     4921 gatttaatca gcgctcccaa tatcaatccg gaatcccata tttttctaaa accagagaac
     4981 ttacaagtaa ccggatcgtt taaagtgcgc ggcgcttgtt tcaagatcgc ccagcttacg
     5041 gaagaagaga aatcgcatgg cgtagtggct tgctcggcgg gaaaccatgc ccaaggtgtg
     5101 gcattagcgg ctaccgctca tggtatcaag tccttaatct gcttgcccga taacgctcct
     5161 atctctaaag tcgaggctac taaatcttat ggggcagatg tatgccttgt cgaaggtgtt
     5221 tacgatgacg cctataacaa ggctttacaa ttgaaggatg agaaaggata cacatttatc
     5281 catccgtttg atgatgagga tgtgatcgcc ggacaaggga ccatcggttt ggagttattg
     5341 gaacaactcc cggaagtaga ggccgtaatc attccgatcg gagggggtgg gctgatctct
     5401 ggagtcgcct atgccatcaa gaacttgaac ccgaatatca gagtttacgg agtgcaagcc
     5461 aaaggagcgc ccagcatgtt aaactctatc gagcatggga aaatcgaacg cctcgaaggt
     5521 gtccgtacca tagccgacgg tatcgccgta aaagaaccgg gaatacatac tttcgatctt
     5581 tgccagcaat atgtggacga gatcgtatcc gtgacagacg atgagatttc caccgctatc
     5641 ctcgcgttga tcgagcaaca taaattaatc gccgaagggg cgggtgccgt agccgtggcc
     5701 gccgccatgt ttaataaagt acccatcaaa gggaaaaaag taatctgttt gatttccggc
     5761 ggaaatatcg acgtgaatat cctttcccgg gtaatcggac gtggtttgca gaaatccggc
     5821 cgctcttgtt ccatgacgat cgaattggta gacaaacccg gacaactaca gcacgtatct
     5881 gaaatcattg cctctaccgg cgctaacgta gtatccgtat atcacgagcg tgtcagccat
     5941 acggctgata tcaatggctg ttatctgcgg ttggagatgg aaacaagaaa tcaacagcaa
     6001 attaatgaga tccggcaatt actcaccgtt tcgggatata agatagtgga aggataaaca
     6061 attcgcccca aagcatacaa ctgattgaca aaccattact gtgccactac tttccatagg
     6121 cgtggcacag ccgtgccatc ctagtggcac acttgtgcca tccttatggc atagctgtgc
     6181 catcacggtg gcacaagcgt gccctaagaa tggcacaagc taaatattaa tatattgtct
     6241 taatgtattc acatactcct ccatcgccaa gcgtcctttg tctgtgatcc ggcaaaccgt
     6301 tcggggcttc ttcccggcaa accccttctc gatctcgata taaccagctt cattaagttt
     6361 gtccaattgg acgctgagat ttcccgccgt agcgttcgtc ttctccttga tatagacaaa
     6421 ctccgcctcc tccaccgata gcaagataga catgatcgcc aaccggagtt gtgagtgcaa
     6481 taaaggatct agttctttaa acattgtttt ttagctttat tattaagaat atgcccggga
     6541 ataatcatca ttaccacaaa tgaaaggcca aaatacaaat accacaagac cgtgacagga
     6601 ccatgattta tcaaactcat cagcatgtag ataactaaga cgaaagcaac taccggagag
     6661 taaatcatcc atttctcccg caagataatg ccatttatcg acacccccaa cccacaatat
     6721 aataacgata aaggaagcat taatataaaa ttgacggatt gttcataaag cacgcaaaac
     6781 gccgcgatca agacgaacgt aagtccaaac atacagccaa acacttgcca tacactggag
     6841 atcgtcttat ccgtataagt caccacggcc ggctcgcaac ctctttgctt atatgaaata
     6901 accggtccga cagcaaacat gagcatccat ccccaagacc aaatataatt ttgcgtatac
     6961 actatcaaag aggatatcac gaccgataag agcacggtaa aataccccca ataaagcaac
     7021 acattgccac tccctacttt catatttcgc ttgctggagt tgatcatctg agtgataata
     7081 tccagacttt ctttttctga taattttcta tcttccataa ctgtatttat tttatcttgt
     7141 tcttcatcca atgtgaaaat gtaaatacgt atccaaagat aaggccattg gtatttctga
     7201 gcaacctttc ggttattatt tttcattcag gcgactccgt tcggaaccga tctcaatctt
     7261 actcttcctt actttctttc cgctattgaa attccatgtc aacgcaacct taaagaccct
     7321 tcctgtaagt ccgttttcat aacgggatga tgttcgataa acatccaacg tactggcgta
     7381 ctcattggct tggttaaaga tattatcgac tgaaactgcc aacaatagct tatcattcaa
     7441 gaatttcttt ctcgccatta ctccaaccgt atgccggggg gcgacctcgc tattaccgga
     7501 atatagccgg ctcgttccac tataccgggc ctccaccgta aaacctgccg gcaacgtaaa
     7561 ggtagcgatc gcattggcaa accctaaata atgagacgaa aaagaagaca attccgtcat
     7621 ccggatatcc tgccgtacgc ctatgaaatt ccctgtcaag ttacaccaag taaagggttg
     7681 atacggcaag ctgaccgcta caaaccaatg gttttcccga tcgtgatttt catacgtgat
     7741 ataggataca tcgggattcg ccacatcttg tttacagaac tcccggatca agtcgtggta
     7801 caagtttcct cctacagtca ccgtataacg ataattataa accaacgtta cactgaaacg
     7861 attgatataa gtaggacgca gataaggatt cccgatctga taactatagt ccgaactctg
     7921 tatacgattc ggattcaagg tatagaacgg aggacgttcg atattacgag catattgccc
     7981 taccagcatc cacctcttga tgggatcgaa cgcataggtc acgttcaagt tcggaaaaag
     8041 atccagataa tcccgactaa aatcctcact tctatccgac gtcttagaat attccgcacg
     8101 tacccccgca acgaacgacc agttcttgat ctccgcagag aaagaggcgt aagctcctac
     8161 aatgttttca ttatatctca aggtatatcc atattcctca ttaggaatcc aactcccact
     8221 agagtttaaa ccctcgtaca aggaatgatc atccatcaac gtataggtat atttggtccc
     8281 gattttcaaa gacatttttt cacgcaaatt cttttggaaa gaaatatcgg ttgtcgccat
     8341 atcataatcc gccgccgcat gactccggta aaccgtatca cggctccaat tagattgttc
     8401 ataacggatc gtatggagat tatccccggt tgatcgctta tttacgaaat cggctatgac
     8461 cttaaatatc gagccttgtt catccatttt acgtaagtaa ttgaccgtag cggaaaacgt
     8521 gttataatca tccttctgtc gataattccc cgtactcttc ataggataag agttctttac
     8581 taaatccgtt tgactccaag atgttccgtc cgaagcttga ttgatatatt cgatctcagc
     8641 tccgacacta ttcagcgaat cgatctcgaa aatagccccg acacgtccat tcccatattt
     8701 ggaatccgta tcatacaaag attgagacac aaacttattc cccaccgttc cgtattccct
     8761 gttggagttc atctctcctt tatcccgggg agtaaaagta cccgataccg ctccattcaa
     8821 gctccatttc ccgacacgtg catttacgga cgccgatgga atataccctt gtaaagatgg
     8881 agacaatgac gtacctaaag atacatatcc ttgcataccg ttatccggac gttgccgcaa
     8941 tgagatcttg atcactccac ccttagttga ggcctcatac tcaactcccg cgatcggtat
     9001 tacctcaatc ctttttatat cctccgattt caaagaccgc aaataagcca gtagctcctc
     9061 tcccgttaaa cgaatctcac ggtcatccac aaacaccttc gccccttgcg ccccattaat
     9121 cgagatcgtt ccatccgaga gccacacacc cggtgcctgc gataataatt ccgtaccatc
     9181 ctttccggca gatggcatga ccgacatgat aaagcggtcc gccttccgct ctatattctt
     9241 cgctcgaaca acgacttccc tcagaacacg gttcgataga tctagaatca aggaatcccg
     9301 ccgttttatc ggtaagatca gctctttccg taaaggctcg tatccgagac attgaacaac
     9361 aagcctatac ttcccagcct ccgcctccat gctaaaatcg ccatcactat tggccacggc
     9421 accccctacc tgtttttctc ccgataaaag cacagcggtc gcatattcca cggcatttcc
     9481 ctccgcatcg gaaacatggg ctttataaac cgtttgtccc gagatctttt gagcactacc
     9541 cccgcctatc gccaaaatcc aaagcgatag cagtaaaaac cgtaccatgg ctctattgat
     9601 ttaccggata atacagtttt aatttgaaag tcgcttcctt atccttcacc tcgcaacttt
     9661 tcaacgcata tccttccgca ggcccttttc cttccagcat atccatttgc caattctcgt
     9721 tctcgtcatg gaatacggac agatcaaact tttcccaatc cacgttttcc agtcggatcg
     9781 taacctttcc tttctcagac ttcgccatgc cataaacagg cttggtatct tttcctgact
     9841 gagccataac taggatattc ccatggttac cacgtatatt tccaatctct acaataatag
     9901 tacgtgcctc tatgcaacca cataccaaca tgaataaaga taatatgaat aaaactcgtc
     9961 tcattttagt atcctcctct ttattattat cactgttact acaaacaagt ttattttata
    10021 aaccttccat agataaaaaa atgcaaagga gctgcgcatc actctttgca catcgcaaat
    10081 atagacaagt ttattttata aaccaaataa tattataaaa tattccaata aaaatttgac
    10141 tctgcaaaat acagccaaaa tcccccacta accctcctag aaaacacgta catgctttca
    10201 aaacaactat tttaagtttg aaacaaagca actttttcgc tatattgcac acatttagaa
    10261 tatatatgaa caggaccaac atacaaataa ctaaagatat gaacgaacga ataattgcta
    10321 tacaagcaga tattacgaca ttggatgtag acgccatcgt aaatgccgca aacaatagct
    10381 tattgggagg tggcggcgta gacggtgcca tccattgggc cgccggtccg gaactccttg
    10441 acgaatgccg gactttacaa ggatgcccga ccggagaggc gaagataacg aaaggttatc
    10501 gattgaaagc ccgtcatgtc atacacaccg tcggtcccat ctaccgaaac ggacaacacg
    10561 gagagccgga gctactggaa aattgttatc gaaactcctt gcgattggcg aaagagaaca
    10621 gactgagaac aatcgctttc ccatcaataa gcaccggcgt atatggctat cctatcgagg
    10681 aggcggcaca gatagcgatc cgcacgatcg ataccttcct aaaagagaat ccggaaatcc
    10741 agcaagtcac gatgtgctgt ttctccggat acgacaaatc ggtttatacg aaagcgctgg
    10801 aacaaattac aactcacgag ccgtaatgtg gaaacaccct tgcttgcgtt cgtgcttgat
    10861 atagcaacga tccgccctgc gcaaatcacg aagcacggag gcaagcacca ttttcaagcg
    10921 gtccttatca atatttaagg tatctttctc atctatctta gtatagcgta cccatgatac
    10981 atcaaacgta gttccgtatt ggtgggcaga gttgagagaa gagttcgtat tcctttttct
    11041 caatttcttg acatcggcaa ccgtacgggt tacactggtt acctttattt tataaatgga
    11101 agcattcaag tttttcaatg agtcttggaa gtttttcccg atatcctcca gcagattagc
    11161 ggcttccggc accaaatacg gaatagagtg cgtcaactcc tctacctcgt aatagtcatt
    11221 cgtcttgatc tccaccatat cccgggaggc gtgctccgct ccttccctcg aagagacagg
    11281 ctctatgccg atcttcttcg caacggacaa atgaacgtca ttcaaatcat taaaatcacg
    11341 attatagctt ccattgtacc aaatcttctt caattcacct cttttctcct tacaagaaga
    11401 aaaagccgtc gccgacacga tcacgaccag caacaacatc acattaaaca cagtcttcat
    11461 cttcatttcc ttcgttttgc ctgacaaaca tacggaaaaa tccgaaattc ccccttaact
    11521 ccaattagtt tttctctaaa tggtagacgg acggctgaaa gatgtgttcc cgtgaaataa
    11581 aacttctccc tttgcatcaa tggataaaga atattactaa ttttgtaact tgattcgaat
    11641 aataaaaaat agcacatctt tttgaagcgt aatttaataa aaggaatagc ggatgattga
    11701 aagaatttat attcttgaaa gcgtagaccc ggtaattttc tacggtgtga ataactctaa
    11761 tatgcaattg atcaagacat tgtttccgaa attgcgtatc gttgcccgtg gaaatgtgat
    11821 gaaagtgatt ggagatgagg atgagtccga gctttttctc aagaaaatcc gtgaggtgga
    11881 aaaatactgt gaggagttta actcgctctc cgaagacgtg attctggata ttataaaagg
    11941 gaaaggtccc acggtcgtga agcaggagaa cctgatcatc cacggcatga atggcaagcc
    12001 gattaccgca cgtaccgaga atcaacagtt attggtaaag gctttcgaga acaacgatct
    12061 ggttttcgcc ac
//
LOCUS       DBMDTB010000109        12053 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_1610_length_12053_cov_13.430723, whole genome shotgun
            sequence.
ACCESSION   DBMDTB010000109 DBMDTB010000000
VERSION     DBMDTB010000109.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 12053)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 12053)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12053
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1610_length_12053_cov_13.430723"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..329
                     /locus_tag="ACZPB4_14225"
     CDS             <1..329
                     /locus_tag="ACZPB4_14225"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="alpha/beta hydrolase family protein"
                     /protein_id="HIR1099406.1"
                     /translation="DMAEYKRRSPVWHAEKLQDPLLIHTNTSDDDVNVVEVEHMIRAL
                     KAEGKKFDYKIFDRAPGAHSFDRTDTKQASEIRLGIYQFLAKHLKPNKPFKSVKDVRK
                     AAYKFN"
     gene            357..1967
                     /locus_tag="ACZPB4_14230"
     CDS             357..1967
                     /locus_tag="ACZPB4_14230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HIR1099407.1"
                     /translation="MKKLFTYVLMLCASLSVSVAQQIQYPEPILNPESCTSIMVGKKA
                     SADGSVMTSHTCDSNYRTWMDIVPSASYDHDTTTTVYTGRMHTEYAEGTRGMIAKGTL
                     PEARSTYQFLNTAYPCLNEKQLGIGETTITGRKALVNKKGMFMIEELQRIVLQRCTTA
                     RDAIRVMGELIEKYGYGDWGECLTIADPKEVWHFEVFGEGPDKIGGVWAAIRIPDDHV
                     GVSANIPRISKVDPKDTDNCMASANVFEVAKRMGFWDGKKPFRFWEAYGGGNYSGEMK
                     SFSIREFFILNKLAPSLRLSYDAEELPISVKPDRQVSVTDVMALLSETYEGTEYDMTQ
                     NLKVAVKKKDSNETDTVISPVANPWMTRDMVNMLNGLKPDAVKSYRLVAVPQCSYSTV
                     IQLRDWLPNAVGGVVWMAYDNPGQSPRIPIFCGTKDLPACFKVCGQHRYREDAAVWAF
                     RRANKLATVRWGATKDRMKASIAHFTEKGQTELPFVESRYKEILTQQGEEAAKEYLTG
                     YTADFAGATMLRWREMGDSFWTQFERGF"
     gene            2041..3210
                     /locus_tag="ACZPB4_14235"
     CDS             2041..3210
                     /locus_tag="ACZPB4_14235"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HIR1099408.1"
                     /translation="MRTFILSCALALGSLSTFAQGYQFTDVVKVPATPVKNQASTGTC
                     WCFATTSFMESELLRMGKGTYDLSEMFIVRQKYMNQLQDNYVRQGRGNIGQGSLSHTF
                     MNAFNQVGIVPEEVYSGINYDSDRHNHAEMVKYIKAIATTAVDMKKRSPEYYKLIDNL
                     FDTYLGKLPEKFTYQGKEYTPKTFAASLGLNMDDYIELTSFTHHPYYQKFEVEVPDNW
                     EHAQMYNLPLDEMMQVADYALNNGYTVCWDGDVSEKGFSFKNGVAINPEVKKVEDYST
                     TDRARFEKMDEKERLEEVYKFEKPFPEVNVTPQVRQEGFEAFVTTDDHLMHLTGIAKD
                     QNGTKYYITKNSWGTERNTFGGYLNMSDSFVRAKTIYIMVHKDAIPKAIKSKLGI"
     gene            complement(3350..5482)
                     /gene="dpp7"
                     /locus_tag="ACZPB4_14240"
     CDS             complement(3350..5482)
                     /gene="dpp7"
                     /locus_tag="ACZPB4_14240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_function: GO:0008239 - dipeptidyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0043171 - peptide catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidyl-peptidase Dpp7"
                     /protein_id="HIR1099409.1"
                     /translation="MKRVWAALLLLAASGQLYADEGMWVLKELNKQNLARMAELGFTP
                     SYDQLYSETDPCVANAVVIFGGGCTGITVSNEGLIFTNHHCGFGAIQQLSSVEHDYLK
                     DGFVSQSKQEELPVPGLTVRYLKETVDVSDRINSQISGIEDEFQRLSAADSIGRVICD
                     SVGNNEFLAADVVPFYSNNKYFLVVYDVYRDVRMVFAPPSSIGKFGGDTDNWMWPRHT
                     GDFSVFRVYVNADNKPAEYNADNKPYTPRYVAEVSMQGYQDKDYAMTIGFPGSTDRYL
                     CSWGVQQRIENSNKPRIEVRGIKQGIWKEAMLASDAVRIKYASKYAGSSNYWKNSIGM
                     NKGLANLNVIERKRAEEMAFADWVAKDQARGAKYGEVLNLLEKGYTSTNKYREALTYL
                     NEAFSSGAEIIRLARMVQSVDIEGATPEEITVFLEDRIQPFFKDYEPSLDQKVLAAMM
                     KIAKERVSPEFLPDIYTSVDKKYKGNYEKYAADVFKKTSLLSYDKIAEMLRNPKQYEK
                     LRKDPAAELSLSVLVSIFQLQQLMGDAEYDIAKGERLYFAGLKEMYPEKALSSDANFT
                     MRLSYGSIGGYRPYDAAWYNYYSTDKGILEKEDPTSDEFWVQPEILDLVRSCDFGPYA
                     NEKGELQLCFLSNNDITGGNSGSPVFDKNARLIGLAFDGNWEAMSGDIAFEPDLQRCI
                     GVDIRYVLFMIDKWGKCPRLIEELRLVR"
     gene            complement(5512..6870)
                     /locus_tag="ACZPB4_14245"
     CDS             complement(5512..6870)
                     /locus_tag="ACZPB4_14245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009860559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HIR1099410.1"
                     /translation="MEKGLLHKQIMDFFVRNFDVRQEKEDELETIESIKKGIEFKGTN
                     LWVLIFATFVASLGLNTNSTAVIIGAMLISPLMGPIMGFGLGLGISDFELIKRSFRNF
                     ATATIFSVITSTLYFLISPISEAQSELLARTQPTVYDVLIAFFGGLAGIVASSTKSKG
                     NVIPGVAIATALMPPLCTAGFGLASGNLYYFFGAFYLYFINTVFISLATFVVVRLLKY
                     PKKVFLDKQREKIVTRYVGIIVFFTIVPSLFLSYNLIRSSYFNDRVRNFVSEELTFPN
                     TQILNKVVTDTSEKKEVKVVLIGQTVPDEMIANARAKLPKYGLKDVHLVVQQGFGQEA
                     TDINELKSLLMQDLYKNSEEVLRAQTIQIDSLKRQVDKYQSYRRLTSELLPEMKVLFP
                     YVVEASCSNTYIVNTETAKPDTVMLVYLKSKTIIKDAERKKIREWLSARVEMKNIKLL
                     IE"
     gene            7003..9090
                     /locus_tag="ACZPB4_14250"
     CDS             7003..9090
                     /locus_tag="ACZPB4_14250"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1099411.1"
                     /translation="MKRYLMLLCLLFMSFVVSSQTTTPDSLKNALQKATSERSRLEIL
                     TNLMDISRNDDILVNAKQLYQEALKANDNYYKEAALTEILRHYINTDQTDSANAYIAK
                     AEQELKGEARTSLVSFMKMIQDTRVIFYTSGEPRRKVLMNCLFKLEEPDKLSPYEKIA
                     CNYVLGMAVSNSVMEENMLQEDFKQGKEYFDNVLAEAEKLPLRYAYNFLPNTYFMLCA
                     YASDPQERGQYATRYLNTILGYSNIPEMRKRPYAINKRHLLSAYSNLAISAEAIGKDL
                     ATSYYREFMNLLKTYPESASAAPEYELYYTSSNYYLGIKDYKKFIEFSDSLINFSKQI
                     PLYKEHVIAYVSAKAAAYDSLRMYKEAYETSKEYAVLLDTLRMQELRKKMENLEIEKG
                     ANELVIEKKSLELELQESKKENYLYMSLLLLALCTVFYIFFRLGKMRSLYQALQKSNE
                     QVLIANQKAQESEEMKTAFIRNMSHEIRTPLNAINGFSELITNDDISMDEKQAFSRII
                     YENCYHLTSMLNNLLEIAQLDSGNDSLPLVPTRIHELCLHEMQQVKKYQEKPEINYVV
                     EGDKENDMILTNRAYFSLIISHLLANANKFTEKGSITLSYHLDSGANLVTLSVTDTGC
                     GIPQDKQEWIFERFTKTNDFIPGSGLGLYLCRLIVNRLNGKIKTDPSYTKGSRFVITM
                     PIATPSKPSEPTD"
     gene            complement(9087..10583)
                     /locus_tag="ACZPB4_14255"
     CDS             complement(9087..10583)
                     /locus_tag="ACZPB4_14255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0140327 - flippase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HIR1099412.1"
                     /translation="MAGGMKRLAKETAVYGLSSIVGRFLNWMLVPMYTRVLAGTGDYG
                     IVTNLYGWTALLLVLLTYGMETGFFRFINKKEEQEPMRVYASVLYCLLGSSALFSVAV
                     FALLPSISAGLGYGDHPEYIGMMAGIVAVDAFCCIPFAYLRYKGKAWRFAGIKLLSIF
                     LNIILNIFFLITCPWLHAHYPEAISWFYRPDYGVGYVFVANVFTTLITLLLLIPDILP
                     GIRAKVDGTVLKQILRYSFPILILGIAGIFNQTADKILFPFLFDDKEYANEQLGIYGA
                     CFKIAVVMVMFTQAFRYAYEPFIFAKNKSDDNKKAYSEAMKYFIIFALFIFLGVMFYI
                     DILKYFVGPAYYPGLRVVPIVMLGELFFGIYFNLSLWYKLIDQTRWGAYFSTIGCVAT
                     VSIILLFGPSYGYMACAWASFFCNLLMMLLSYFVGQKKFPIEYDLKSAFLYFGVATVL
                     YVAGMALPIQSEWLRLGYRTILLGVFIAFMVKRDLPLRELPYVGRFFR"
     gene            complement(10595..11620)
                     /gene="ruvB"
                     /locus_tag="ACZPB4_14260"
     CDS             complement(10595..11620)
                     /gene="ruvB"
                     /locus_tag="ACZPB4_14260"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HIR1099413.1"
                     /translation="MEDDFDIRDARMPENEREYENVLRPLSLRDFSGQAKVVENLKVF
                     VMAARMRKEALDHVLLHGPPGLGKTTLSNIIANELGVGFKVTSGPVLDKPGDLAGVLT
                     SLEKNDVLFIDEIHRLSPIVEEYLYSAMEDYRIDIVIDKGPSARSIQIDLAPFTLIGA
                     TTRSGLLTSPLRARFGINMHLEYYDMETLTKIVLRSANILNVKCELNAAREIASRSRG
                     TPRIANALLRRVRDFAQVKGNGDIDKAIACFSLEALNIDRYGLDQIDNKLLTTIIDKF
                     KGGPVGLTTIATALGEDPGTLEEVYEPFLIKEGFIKRTPRGREVTDLAYTHLGRSRVG
                     EQGSLFD"
     gene            11749..>12053
                     /locus_tag="ACZPB4_14265"
     CDS             11749..>12053
                     /locus_tag="ACZPB4_14265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009016496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-bladed beta-propeller"
                     /protein_id="HIR1099414.1"
                     /translation="MKLILTIFAMILFLITGCESGKQPANDFLTVDITANYPKKELIL
                     QDFLDVEYIPLETNEEFITSASMQAIGKNLIILRNKNGQDGDIFIFDRTGKGQRKINR
                     "
BASE COUNT         3532 a         3123 c         2519 g         2879 t
ORIGIN      
        1 aggatatggc ggaatacaaa cgccgctcac cggtctggca cgcggaaaaa ctacaagatc
       61 ccctgctcat ccataccaat actagcgatg atgacgtgaa cgtagtggaa gtagagcata
      121 tgatacgtgc tctcaaggcc gaaggaaaga agttcgacta caaaatattc gaccgtgctc
      181 ccggtgccca tagcttcgac cggaccgaca cgaaacaagc ttccgagata cgactcggca
      241 tctaccagtt cctcgccaag catctaaaac ccaataagcc attcaaatcc gtaaaagacg
      301 tacgaaaagc ggcctacaaa tttaattgat acaaacatct aaataacaca agaaagatga
      361 agaaactttt tacctatgtt cttatgcttt gcgccagcct atccgtttcg gtagcgcaac
      421 aaatccagta tccggagccg atcttgaacc cggagagttg tacgagtatc atggtcggca
      481 aaaaagcctc ggcggatggc tccgtgatga ctagccacac ctgcgatagc aattaccgca
      541 cttggatgga tatcgtacct tccgcctcgt acgatcacga tacgacaacc acggtctata
      601 ccggacgtat gcataccgaa tatgccgagg gaacccgggg gatgattgcg aaaggaacac
      661 tgcccgaagc gcggtctacg tatcaattcc tcaacacggc ctatccttgc ctgaacgaga
      721 agcaactagg catcggggaa acaacaatca ccggccggaa agcccttgtc aacaagaaag
      781 gtatgttcat gatcgaggaa cttcagcgaa tcgtcttaca acgttgcacg accgcccgtg
      841 atgccatccg tgtgatgggc gagttgatcg agaaatacgg atatggcgac tggggcgagt
      901 gccttacgat agcggatcca aaagaggtat ggcatttcga ggtcttcggc gagggtccgg
      961 ataagatcgg tggcgtatgg gcggcgatcc gtatccccga cgatcatgta ggcgtatcgg
     1021 cgaatatccc gcgtatctct aaggtcgatc cgaaagatac ggacaattgc atggcttccg
     1081 ccaacgtatt cgaggtagcc aagcgcatgg gcttctggga cggaaagaaa ccgttccgct
     1141 tctgggaagc atatggaggc ggaaattatt ccggtgagat gaaatccttc agtatccgtg
     1201 agttctttat attgaataaa ttagcgcctt ccttacgttt atcgtatgac gcggaagaac
     1261 ttcccatcag cgtaaagccg gaccggcaag tatccgtaac ggatgtgatg gctctcctct
     1321 ccgaaacgta cgagggtacg gaatacgata tgacccagaa cttgaaagta gccgtaaaga
     1381 aaaaagatag taacgagacc gatacggtta tcagtccggt agccaatcct tggatgactc
     1441 gggatatggt gaacatgttg aatgggttaa aaccggacgc cgtaaaaagc taccgtttgg
     1501 ttgccgtacc acaatgctcc tactctaccg tgatccagtt acgtgactgg ttacccaatg
     1561 cagtaggcgg cgtggtttgg atggcctatg ataatcccgg acaaagcccc cgcatcccca
     1621 tcttctgtgg gacgaaagat ctcccggctt gcttcaaggt ttgcggacag caccgttacc
     1681 gggaagatgc cgccgtatgg gctttccgtc gtgccaataa actcgctacc gtacgttggg
     1741 gagcgactaa agatcgtatg aaagcatcta tcgcccattt tacggagaaa gggcagacag
     1801 aacttccttt cgtagagagc cgttacaaag agattcttac ccaacaaggt gaggaggccg
     1861 caaaagaata cctaaccgga tataccgccg atttcgccgg agccacgatg ctacgctgga
     1921 gagaaatggg agactcattc tggacccaat tcgaaagagg cttctaatca ccacatccga
     1981 tagtagagac gaggcacacc ccgtctctac aataataata taaacttaaa ttcatataca
     2041 atgagaacat tcattctatc atgcgcctta gcgttaggtt ccttgagcac attcgctcaa
     2101 ggctaccaat ttacggatgt agtaaaggta cccgccacgc cagtcaagaa tcaagcatcc
     2161 acgggaacct gctggtgctt cgccacgacc tctttcatgg agtcggaatt actccgtatg
     2221 ggaaaaggga cgtacgatct ctctgagatg tttatcgtcc gccagaaata catgaaccag
     2281 ttgcaggata attatgtccg ccaaggcaga ggtaatatcg gtcaaggaag tctttcccac
     2341 accttcatga acgctttcaa ccaagtaggt atcgttccgg aagaggtgta ctcgggtatc
     2401 aactacgatt ccgaccggca caatcatgcc gagatggtaa aatacatcaa ggcgatcgca
     2461 acgacagccg tggacatgaa gaaacgtagc ccggaatatt acaaactaat cgataaccta
     2521 ttcgatacct acctaggcaa gcttccggag aaattcactt atcaaggcaa ggaatatacc
     2581 ccgaagacat tcgccgcctc cctagggttg aatatggacg attatatcga gctgacaagc
     2641 ttcacgcatc atccgtatta ccagaaattc gaggtagagg ttcccgataa ctgggaacat
     2701 gcgcaaatgt ataacctccc gttggatgag atgatgcaag tcgcagatta tgctttaaat
     2761 aatggttaca cggtatgttg ggatggcgac gtgagcgaga aaggcttctc tttcaagaat
     2821 ggcgtggcga tcaacccgga ggtaaagaag gtggaagatt actcgactac cgaccgtgct
     2881 cgctttgaga aaatggacga gaaggaacgt ctggaggaag tctacaaatt cgagaaacct
     2941 ttcccggaag taaacgtcac cccgcaggtc cgtcaagaag gcttcgaggc gttcgtcacg
     3001 accgatgacc atttgatgca ccttaccggc atcgccaaag atcaaaacgg cacgaaatat
     3061 tatatcacga agaactcttg gggaaccgag cgtaatactt tcggcggata cttgaacatg
     3121 tccgatagtt ttgtccgtgc caagacgatc tatatcatgg tacataagga tgcgatacca
     3181 aaggcaatca agtctaaatt aggcatttag aacttcccta tcgtatagga tattacaatg
     3241 cccatcgtaa ggttgttaga ataggcattc aaagcacctt acaatgggca ttattagctc
     3301 cttagaatgg gcatccgcga aaatcatgga tgcccatctc ttttttctct catcgaacga
     3361 gcctcaactc ttcaatcaac cttgggcatt taccccattt atcgatcatg aaaaggacat
     3421 agcggatatc tacgccgatg caacgttgca aatccggttc aaaagcgata tcaccactca
     3481 tcgcctccca gttaccgtcg aaagcaagtc cgatcaaacg ggcgttttta tcgaataccg
     3541 ggctaccgga attaccacca gtgatatcat tgttcgagag gaagcacagc tgcaattccc
     3601 ctttttcatt cgcataaggt ccgaaatcac agctacgaac cagatccagt atctccggtt
     3661 gtacccagaa ctcatcgctc gtcgggtcct ctttctctag gataccttta tccgttgagt
     3721 aataattgta ccatgcggca tcataaggac gataccctcc gatagaacca tagcttaaac
     3781 gcatcgtgaa attagcgtcg gaagacaaag ctttctccgg atacatctcc ttcaagcccg
     3841 cgaaatacaa acgttctccc ttagcgatat catactccgc atcgcccatc aactgctgta
     3901 actggaagat agacaccaat acggacaagc tcagttccgc cgccggatct tttctcaatt
     3961 tctcatattg cttcggattt ctcaacatct cggcgatctt gtcgtacgac aataaggaag
     4021 tcttcttaaa tacatccgcc gcatatttct cataatttcc tttatacttc ttatcaacgc
     4081 tcgtataaat atccggcaag aactccggag atacacgttc tttcgcgatc ttcatcatcg
     4141 cggccagtac cttctgatcc aaagacggct cgtaatcctt gaagaacggt tggatacgat
     4201 cctctaaaaa gacagtaatc tcttccgggg tagctccttc aatatccacc gattgcacca
     4261 tacgggccaa acgaataatc tccgctccac tagaaaacgc ctcattcaaa taggtcaaag
     4321 cctctctata tttattggtc gaggtatatc ctttttccag caaattcaag acctcgccat
     4381 atttagcgcc ccgggcctga tctttcgcta cccaatcagc gaaggccatc tcctccgcac
     4441 gtttacgttc gatcacgttt agattcgcca atcctttatt cataccgatc gagttcttcc
     4501 aataattgga gcttcccgca tacttagaag catatttgat acgtacagcg tcgctagcca
     4561 acatcgcctc tttccagatg ccctgcttga tgccacgcac ctcgatacga ggcttattac
     4621 tattctcgat acgctgttgc acgccccaag agcacaaata acgatccgtg cttcccggaa
     4681 aaccgattgt catggcataa tctttatctt gatagccttg catagacacc tccgctacat
     4741 atctcggggt ataaggctta ttatccgcgt tgtattccgc cggtttatta tctgcgttga
     4801 cgtacacacg gaatacggaa aaatcaccgg tatgccgagg ccacatccag ttatccgtat
     4861 cgccaccgaa cttaccgata gagctaggcg gagcgaaaac catacgcacg tcacgataaa
     4921 catcgtacac caccaagaaa tatttattat tgctatagaa agggacaaca tcagccgcta
     4981 ggaactcatt atttcccacg gaatcacaaa tcacacgacc gatagaatca gccgccgaca
     5041 aacgctggaa ctcatcctcg ataccggaga tctggctgtt gatacgatcg ctcacgtcta
     5101 cggtctcttt caggtaacgt accgtcaagc ctggaaccgg aagttcttcc tgtttacttt
     5161 gagagacaaa accatctttc agatagtcgt gctccacact actcaactgc tggatggctc
     5221 cgaaaccaca atggtgattc gtgaagatca atccctcgtt agagaccgta ataccggtac
     5281 atcccccacc gaagattacc acggcgttcg ccacgcaagg atccgtctca ctatacaact
     5341 gatcatagga tggggtaaaa cccaactcag ccattctcgc caaattctgc ttatttaatt
     5401 ccttcagcac ccacatgccc tcatcggcat ataactggcc ggaagcggct aaaagcaaca
     5461 aagccgccca cactcttttc atcaacttca ttctactctg attagtctaa attattcgat
     5521 tagtaattta atatttttca tttccacacg agccgacagc cattccctga tcttcttacg
     5581 ttccgcatct ttaatgatcg tcttactttt cagataaacc agcataaccg tatccggctt
     5641 cgccgtctcc gtattcacga tatacgtatt cgagcaagat gcctcaacta cataggggaa
     5701 aagaaccttc atctccggga gcaactcgga tgtcaaacgc ctataactct gatatttgtc
     5761 aacctgtcgt tttaacgaat ctatctggat ggtctgcgca cgtagtacct cctcgctatt
     5821 cttatataaa tcctgcatca agaggctttt caactcattg atatccgtgg cctcttgtcc
     5881 gaagccttgt tgcacgacta aatgcacatc tttcaatcca tacttaggca atttagcccg
     5941 ggcgttagcg atcatctcat ccggtaccgt ctggccgatc aagactactt tcacctcctt
     6001 tttctcgctc gtatccgtaa cgaccttatt caagatttgc gtattcggga aagtcaactc
     6061 ctccgatacg aagttacgta cccgatcatt gaaataacta ctccggatca agttataact
     6121 caagaaaagg ctcggtacga tcgtgaaaaa aacaatgata cccacgtaac gagtcacgat
     6181 cttttcccgt tgtttatcca agaaaacttt cttcggatat ttcaacaaac gaacgacgac
     6241 aaacgtagcc aaactgataa aaaccgtatt gataaaatac agataaaaag caccgaaaaa
     6301 gtaatacaaa ttgccactcg ccaacccgaa tccagccgta caaagcggag gcatcaaagc
     6361 cgtagcgata gctacacccg gaatcacgtt acccttactc tttgtcgagc tcgccacgat
     6421 tccggccaga ccaccgaaga aagcgatcaa tacatcgtat accgtaggtt gcgtacgggc
     6481 aagcaactcg ctttgcgcct cgctgatcgg tgagatcaag aaatataagg tggaggtaat
     6541 cacgctaaaa atagtagcgg tagcgaaatt acggaacgaa cgcttgatca actcgaaatc
     6601 ggagattccc aatcccaagc cgaatcccat gatcggtccc atcagcggcg agatcaacat
     6661 cgcgccaatg atcactgccg tagagttggt atttaacccg agagaagcga caaacgtagc
     6721 gaaaataagt acccataagt tcgtcccctt aaactctatc ccctttttaa tggattctat
     6781 cgtctccagc tcatcttcct tttcctgcct gacgtcgaaa ttacggacaa aaaaatccat
     6841 aatctgttta tgtagcaatc ctttttccat gcggtattaa tcttgtccca tatttatgca
     6901 aagatattcc aattgtttgt ttttctaact atttaatagc ttttttatgg tgagattacg
     6961 tatatttgca tttacaatac aacaacaaga gatcctattt gtatgaaacg atatctaatg
     7021 cttttatgct tattgtttat gtcctttgtc gtttcatctc aaacgaccac accagactca
     7081 ctcaaaaacg ccttgcaaaa agcaacctcc gaacgctcaa gattggaaat ccttaccaat
     7141 ttaatggaca tctcacgaaa cgatgacata ttagtaaacg ctaaacaact ctatcaggaa
     7201 gccttaaaag cgaatgacaa ttactataag gaagcggcat tgaccgagat tctccggcat
     7261 tatatcaaca cggaccagac cgatagcgca aacgcctaca tcgccaaggc cgagcaggag
     7321 ctaaaaggag aagccagaac cagcctcgta tcgttcatga aaatgatcca agatacgcgc
     7381 gtcatattct acacatccgg tgaaccgaga aggaaagtcc tcatgaattg cctattcaag
     7441 ctggaggaac ccgacaaatt gtctccctat gagaaaatag cctgtaatta tgtacttggt
     7501 atggctgtca gcaacagcgt catggaagag aacatgcttc aggaggactt caagcaaggg
     7561 aaagaatatt tcgataatgt tctggccgag gcggaaaaac tgcccctacg atatgcgtac
     7621 aatttcttgc ctaacaccta tttcatgcta tgcgcttatg cgagtgaccc tcaagaacga
     7681 ggacaatatg ctacccgtta cctaaacacg atcttgggct actctaatat cccggagatg
     7741 aggaaacgtc cttacgcgat caacaaacgc catttattaa gcgcttattc aaaccttgcc
     7801 attagcgccg aggctatcgg aaaagatttg gcgacctcct attaccgtga gttcatgaat
     7861 ctgttgaaaa cttatccgga atcagctagc gccgccccgg agtatgagct ctactacacc
     7921 tcatcgaatt attacctagg tattaaggac tataagaaat tcattgagtt cagcgactct
     7981 ttgatcaatt tctccaaaca gataccgctt tacaaggaac atgtaatcgc ttatgtatcc
     8041 gccaaagctg ccgcctacga cagcctccgg atgtacaagg aggcctatga gacatccaag
     8101 gagtacgcag tattgctaga taccttgcgt atgcaagaac tcaggaagaa aatggaaaat
     8161 ctggagatcg agaaaggggc gaacgagttg gtgatcgaaa agaaatcatt ggaactggaa
     8221 ttacaggaaa gcaagaaaga gaattacctg tatatgtcct tattgcttct agctttatgc
     8281 accgtattct atatcttttt ccggctaggc aaaatgagat ctctttatca agcactacaa
     8341 aaatccaatg agcaggtctt gatagcgaac cagaaagcac aagagagcga ggagatgaag
     8401 accgccttca tccggaatat gtcgcatgag atacggactc ccttaaacgc aatcaacggt
     8461 ttctcggaac tcatcaccaa cgacgatatc tccatggacg agaaacaggc tttcagccgt
     8521 attatctatg aaaactgtta ccacttgact tccatgctga acaatctcct tgagatcgcc
     8581 cagctcgata gcggcaatga ttcccttcct cttgttccca cacgtatcca tgagctttgt
     8641 ttacatgaga tgcaacaggt aaagaaatat caagagaagc cggagatcaa ctatgtggtg
     8701 gaaggcgata aggagaatga tatgatcttg accaaccgtg cttatttcag tttgatcatc
     8761 tcgcatctgc tggcaaacgc gaataaattc acggagaaag gaagcatcac gctttcatac
     8821 catctggata gcggagccaa tttagtgacc ctgtcggtaa cagatacggg ttgcggcatc
     8881 cctcaagaca aacaggaatg gatattcgag cgtttcacga agaccaatga tttcattccc
     8941 ggctctggcc tggggcttta cctatgtcgc ttgatcgtta accggctaaa cggtaagata
     9001 aagacagatc cgtcttatac gaaaggctca cgcttcgtta tcacgatgcc aatcgccacg
     9061 ccgtccaagc cctccgaacc taccgattaa cggaagaaac gtcctacgta cgggagttct
     9121 cgtaaaggta aatccctttt aaccataaat gcgatgaata cgcctaataa gatcgtgcgg
     9181 tatcccaacc ggagccattc agactgtatc ggcagtgcca tgcctgccac gtataacacc
     9241 gtcgccactc cgaaataaag aaatgcggat ttcaagtcgt actcgatcgg gaatttcttt
     9301 tgtcctacaa aataggataa aagcatcatc aataaattac aaaagaacga tgcccacgca
     9361 caagccatat aaccgtacga gggaccgaac agcaagataa tagagaccgt ggccacacat
     9421 ccgatcgtgg agaaataggc gccccatcgt gtctggtcga tcagcttata ccataaggag
     9481 aggttgaaat aaataccgaa gaacaactcg cccagcatca cgatcggcac tacccgtaat
     9541 ccgggataat aagccggccc gacaaagtac ttcaagatat cgatatagaa cattaccccg
     9601 aggaagataa acaaggcgaa tatgatgaaa tatttcatcg cttccgagta ggctttctta
     9661 ttatcatcgc tcttgttttt agcgaaaata aacggctcat aggcataccg gaaagcctgc
     9721 gtgaacatca ccatcaccac ggcgatcttg aagcatgcgc cgtatatacc caattgctcg
     9781 ttcgcgtact ccttatcatc aaacaagaat ggaaacagga tcttatctgc cgtctggtta
     9841 aagataccgg caatacctag aatgaggatc gggaaggaat aacgcaagat ttgtttcaat
     9901 accgttccgt ctactttcgc ccgtatgccc ggcaagatat ccgggatcaa aagcaataag
     9961 gttatcagtg tcgtaaacac gttcgccacg aatacatagc ctaccccata atccggacga
    10021 tagaaccagc ttatcgcctc cggatagtgc gcatgcaacc acggacaagt gatcaagaag
    10081 aatatattca agataatatt caagaaaata ctcagcaact taatcccggc gaaacgccat
    10141 gctttcccct tataccgaag ataagcgaac ggaatgcaac aaaaagcgtc taccgccacg
    10201 atacccgcca tcatcccgat atactccgga tggtcgccat atcccaagcc ggcactaata
    10261 gatggtaaca aagcgaaaac cgctacgcta aacagcgccg aacttcccag caagcaatac
    10321 agcacggaag catacacccg catcggctct tgctcctctt tcttattgat gaaacggaag
    10381 aaccccgtct ccatgccata agtaagcaag accagcaaca gggctgtcca accatataaa
    10441 ttcgtcacga tcccataatc ccctgttccg gccaacacac gtgtgtacat cggcaccaac
    10501 atccaattca ggaaacgccc cactatacta ctcaatccat aaacggctgt ctctttagcg
    10561 agccgcttca ttcctcctgc catatcgtat ctgtctaatc aaataaagaa ccttgttccc
    10621 ccacccggct acgtcccaga tgggtataag ctaaatcggt gacctcacgg ccacggggcg
    10681 tgcgtttgat aaagccctct ttgatcaaga aaggctcgta cacttcttct agcgttccgg
    10741 ggtcctcgcc caaagccgtg gcaatcgtcg ttaatccgac cgggcctccc ttgaatttat
    10801 caatgatcgt cgtcagcaac ttattatcga tctgatccaa gccataccgg tctatattca
    10861 acgcctccag agagaagcaa gcgatcgcct tatcgatatc tccgttcccc ttcacttgag
    10921 cgaaatcacg cacacggcgc aataaagcgt tggcgatacg aggcgtaccc cggctacggg
    10981 aagcgatctc ccttgcggcg ttcaactcac attttacatt caagatatta gcactacgga
    11041 gcacgatctt cgtcagcgtc tccatatcat aatactccaa gtgcatattg ataccgaaac
    11101 gggcacgcag cggactagtc agcaagccgc tacgggtcgt agcgccaatc aatgtaaacg
    11161 gagccaaatc gatctgtatc gagcgggcgc tcggtccttt atcgatcacg atatcgatcc
    11221 ggtaatcctc catagcggaa tacaggtatt cctccacgat cggactcaac cggtgaatct
    11281 catcgataaa aagcacgtcg ttcttctcca gcgaggtcaa taccccggcc agatctcccg
    11341 gcttatccag caccggcccc gacgtgacct tgaaaccaac ccccaactcg ttcgctataa
    11401 tattcgacaa cgtcgtcttt cccaacccgg gaggtccatg caaaagcaca tgatccagcg
    11461 cctccttacg catgcgggca gccatgacga acaccttcag gttctccacc accttcgcct
    11521 gtccgctgaa gtcacggagc gaaagcggcc gaagcacgtt ctcgtactct cgctcgtttt
    11581 ccggcatccg ggcatccctt atatcaaaat catcttccat attcacgttc attgacttgc
    11641 aaagataatg ttaaacaaca cattcacgaa aatagatgta taaaatattt ttctgacagt
    11701 gagaaaagca tatgtttgct aaagggacac ctttaaaaac atactaccat gaaacttata
    11761 ctcacaatct ttgcgatgat cctgttcctg ataacgggat gcgaaagtgg caagcaaccg
    11821 gctaacgact ttttaaccgt ggatatcacg gcaaattatc cgaagaagga actgattctt
    11881 caagactttt tggatgtgga atacatccca ttagaaacga atgaggagtt cataacctca
    11941 gccagcatgc aagccatcgg caaaaatctc ataatcctta gaaacaagaa cggacaagac
    12001 ggagatatat ttatcttcga ccggaccgga aaaggccaga gaaaaatcaa ccg
//
LOCUS       DBMDTB010000110        11981 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_1618_length_11981_cov_11.917088, whole genome shotgun
            sequence.
ACCESSION   DBMDTB010000110 DBMDTB010000000
VERSION     DBMDTB010000110.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 11981)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 11981)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11981
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1618_length_11981_cov_11.917088"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..741
                     /locus_tag="ACZPB4_14270"
     CDS             <1..741
                     /locus_tag="ACZPB4_14270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010536568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohexomutase domain-containing protein"
                     /protein_id="HIR1099415.1"
                     /translation="PHGNFSHNPEPIPENLTEISDLMGHAKADVGFVVDPDVDRLAII
                     CENGEMFNEEYTLVAVSDYVLSHTPGNTVSNLSSSRALRDVTRAHGCEYNAAAVGEVN
                     VVTKMKATNAVIGGEGNGGVIYPASHYGRDALVGIALFLTHLAKKKMKTSELKASYPP
                     YFISKQKVQLTPEIDVDAILAKVKEKFSQYDITDIDGVKIDFPDKWVHLRKSNTEPII
                     RIYSEAHTMEEAEELGGQLIQIINEMCK"
     gene            855..2510
                     /locus_tag="ACZPB4_14275"
     CDS             855..2510
                     /locus_tag="ACZPB4_14275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6377 domain-containing protein"
                     /protein_id="HIR1099416.1"
                     /translation="MNKLIKVILFLIVGMVQAFAWGGLRGDTLAKELDEAVLNRSFYL
                     QQREQRITQLKDMFLLSKISLWQEYEINHQLYEEFKKIQQDSAIYYIKRNMEIASFMK
                     DTARIYTSRLRLATLYAFSGMYRESESLLRSIDRELLSKEQKQDFYEAYYSFFSYYST
                     NLDSFEYRKQLDLYKDSLLSVLDTVSYRYKINLAQKYLAHGQARSAEKVLIPLLEKEE
                     RYNPNFAMITYLLGDVYDMDGRTDLARDYYTLSVIADIKRAFLDSGSIQKLALNYCES
                     GDLSNALKYAQLAIEGAVTCNIQFRMNEISKFYPIINASYQTREAQGKRQLMTYFLSI
                     SLLTLFLILSLAYVYRQMRKISAIREELVNTNARLVKLNREISETNDLLQERNIQLSE
                     SNHIKEEYIAHFLDLCSTYINKLEDYQKSLQKKAMNKQLDELFKMLRSTRMVENEVEA
                     LYVNFDRIFLGLYPTFVKDFNALLQPEERIVLKSEDLLNKELRIFALMRLGVTDSVRI
                     AAFLRCSLSTIYNYRTKVRNKALVPRDEFEGWVMRIGINRNPL"
     gene            2660..4042
                     /locus_tag="ACZPB4_14280"
     CDS             2660..4042
                     /locus_tag="ACZPB4_14280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-disaccharide hydrolase"
                     /protein_id="HIR1099417.1"
                     /translation="MKIKLMIAAVIACLVFTGFTKENVSDTVDHNAWKTTGVVVIQND
                     VLTLAGSNARALLNDGKGYTNFELDMDVRTTTGGKGYIGIHTDATDRKGYRIALNNDR
                     EDPVWWRMTGSLVSVRNLTKSFVKENEWFKMNIRVEGRLIRVRINGETVVEYIEPSKP
                     FRLKENAKALLSQGTISLVGTGRGNLQFKNISLEAFSAKGIDIPAQWANAVDEQTDEI
                     IRLHQEDFPVLDYHVHLNGGLTKEVAARQSRWTGVNYGLAINCGIGFSITNDTELYNY
                     LDTMRTQPFILAMQAEGREWVTTFSEAARNSFDYVFTDAMTFLDHKGRRTHLWVNKEV
                     IIDDEQAYMDMMLDRICSVLEEPVDMYVNSCFLPYAMSDRYDMFWTEERIDRFVNALA
                     KSGKALEINELYHIPNKAIIQKAKAAGVKFTFGSNNITPEVGTLDYCIRMKKECGLTA
                     QDMYKPHINI"
     gene            complement(4386..4877)
                     /locus_tag="ACZPB4_14285"
     CDS             complement(4386..4877)
                     /locus_tag="ACZPB4_14285"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016817 - hydrolase activity, acting on
                     acid anhydrides [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0009132 - nucleoside diphosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HIR1099418.1"
                     /translation="MRTEWFPLVNEEGETIGKATRKECHSGSKLLHPVIHLHIFNKDG
                     DLYLQKRSMNKDIQPGKWDTAVGGHIDYGESVEEALRREVREELGITDFTPVFIKRYI
                     FESSIEKELVNSFRTTYDGPITPDPEELDGGRFWPIEEIKENLGKGAFTPNFEKEFTA
                     IFL"
     gene            complement(4881..6980)
                     /locus_tag="ACZPB4_14290"
     CDS             complement(4881..6980)
                     /locus_tag="ACZPB4_14290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HIR1099419.1"
                     /translation="MKVCIAEKPSVAREIAEVLGATQRMNGYIEGNGYQVTWTFGHLC
                     TLKEPHEYAENWKRWSLGSLPMIPPRFGIKLIENPTYEQQFKVIESLMQNAEMVINCG
                     DAGQEGELIQRWVMQKAGCKCPVYRLWISSLTEEAIREGFQKLKEQTEFNKLYEAGLS
                     RAIGDWLLGMNATRLYTLRYGQNRQVLSIGRVQTPTLALIVNRQAEIDNFKPEPYWEL
                     KTIYRNTTFSATKGKFTKKEEGEAFLEKVKEQDFTVTSITEKKGKEFAPRLFDLTSLQ
                     VECNKKFAFTADDTLKLIQSLYEKKVTTYPRVDTTFLSDDIYPKVPNTLKGLVDYTEL
                     TAPLMNQKLPKSKKVFDNSKVTDHHAIIPTGVPARNLTDTERKVYDLVARRFIAAFYP
                     DCEISTTTVLGQVDKVEFKVTGKQILKPGWRVVFGAEQKDPEAEPTEEEGVLPDFVKG
                     ESGPHKPILKETWTQPPKPYTEATLLRAMETAGKLVDNDELRDALKENGIGRPSTRAA
                     IIETLFKRNYIRKERKNLYPTATGAELIGTIHEELLKSAELTGLWEKKLRQIERGTYE
                     ARTFLDELKQMVNEVVINVLSDQTRRTITIEDTSKAAKETPKDEPKEKKEKKPRKPRA
                     KKEKEKAEATPELELPSTDKPVCPICHKGSILRGKTAYGCSEYKNGCTFRLDYATYGN
                     NLTDEELGTVISKLKSI"
     gene            7169..7747
                     /locus_tag="ACZPB4_14295"
     CDS             7169..7747
                     /locus_tag="ACZPB4_14295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma-70 factor"
                     /protein_id="HIR1099420.1"
                     /translation="MADIDSEKERRLVADLLEGDESAFCELYALYKDRLMWFSLKFLK
                     SRDMAEDVFQDAFASIWQNRRFLNPNVPFGPYVYTIVKNRILNLLAGLDRELELRDKI
                     RSASLDSTNETEDSVLDTDLNALLDKALETLSPQQKRVFDMSRKDMKSHKEIADSLGI
                     SVYTVQQHISTALKVIRAFLAKYAETYMELLL"
     gene            complement(7759..9561)
                     /locus_tag="ACZPB4_14300"
     CDS             complement(7759..9561)
                     /locus_tag="ACZPB4_14300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5107 domain-containing protein"
                     /protein_id="HIR1099421.1"
                     /translation="MKAYRLILSLMASVAVGTAFSQTTGVVCEEFDQIQLTHVLTPTG
                     PLPTALDPNGVYPYMSYSETSNRPVPKRYRMISLENEKVKAIICPDLCGKVISLTHKE
                     SGKEVLYRPDVIKYTRILPRFYFVAGGIEVSFPISHSPTQNEPVLYQIDHTGDRTYVT
                     CGERESHYGMQWSVEYSLGDKDECLTQRVVYYNPGKQAYPWMSWSNAALPCAPDTQYD
                     FPNGTVLSHASTLDTIDWKTEGTHHERDIKEMTGYFWKTKDVNAFGAYTPSLGSGLYH
                     IADESSTPGIKLWSYGVAGDKEWSMLSTPDRQPYVEIQGGPISDQSIKLELRPGEKKN
                     HVEYWIPTDHPLDIYSLKVPALRLRPIDRIPLFDWARKNESSIWIALADAYKNKSMLP
                     AAPYPEDGQWAPSGMEDLDDAFRWAIQISPQPERDYWQFHYGTWLAGRERVEEAIEQL
                     SIPDIDLAKALLARLYVRRQAWEKARDAYAAIPETSWLNLHPQLVIERDKVLKKFGTE
                     ALPERQKWLDKINASSDEWVAERKVQLLIDRKQYQEAKDLLQSTHFQKVHQTYTRTGL
                     WEQINEGLGLSPQPVPEQLGEDRLARFGAYREYE"
     gene            complement(9585..11408)
                     /locus_tag="ACZPB4_14305"
     CDS             complement(9585..11408)
                     /locus_tag="ACZPB4_14305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4091 domain-containing protein"
                     /protein_id="HIR1099422.1"
                     /translation="MKKYFLAVASFFIYSHISLGQVYPGQMDSTFVPVRSHHYDPELT
                     FDFCVNEPAWSNQAGIHSAFGSTDRLYFRKEVPVNHDNDLSSSYSTTVWRGERANAQI
                     LVWSSEALEQVRVSTQDLRSAEGNIIPKDRITFELVRYVLSNYPYAEKKAICGESPYK
                     SGFLMPDRFETLDRFDLPSQTTRPVWMMVDVPRGTAPGTYKGQVEVRAKGKAPQLLNL
                     EIVVQNQLLPYPKDWKYRLDLWQNPWAVAWYNHVEPWSPEHKMLLKQHLKHYADAGGT
                     YITTYGVHSPWSDNSYMIEGGMIEWIKKADGTWAFDYKIFDEYVELAMECGIDEAITL
                     YTPIPWGFRHRYKDEATGDYSYINWTPSSKEFKKMWNIFLTDFKFHLEAKSWLDITYI
                     GINENPMEETLAAINVVRNHDKCWKITYAGNWHKELDGLLDDYSFLYGEEPTIAEQKA
                     RAATGRTSTVYVCCNPPIPNNFVFSPPIEGRWISWYVMAYGYDGFLRWAYDAWPEDAD
                     RDARHGSWAAGDCYMVYPGGKSCIRFEKMREGIVDFEKVRILRELTTQSGNAQAQGLL
                     KQLDQHLSIFPKEKEFDENKISANVRKGNLIIRQLSDLLAK"
     gene            complement(11532..>11981)
                     /locus_tag="ACZPB4_14310"
     CDS             complement(11532..>11981)
                     /locus_tag="ACZPB4_14310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RagB/SusD family nutrient uptake outer membrane
                     protein"
                     /protein_id="HIR1099423.1"
                     /translation="AEALYEKNGQITDEQLDLTINDLRNRANMPRLTNAFVATNGLNM
                     QEEIRRERTVELAFEGYRRDDLRRWGTAETVLPLAIRGVKFVGTEYQQKFPELVIGQD
                     IQVDSDGFIIAQPASARKFQTPKHWLSPIPLQQVQLSKGTLEQNPGW"
BASE COUNT         2955 a         2748 c         2918 g         3360 t
ORIGIN      
        1 cctcatggaa acttctctca taatccggaa cccattccgg aaaacttgac agagatctcc
       61 gatttgatgg gacatgcgaa agcggatgtc ggtttcgtag tagatccgga cgtagaccgt
      121 ttggcgatta tctgcgagaa tggcgagatg ttcaacgagg aatacacctt ggtcgctgtc
      181 agtgattacg tattaagcca tactccgggt aatacggtaa gtaacctgag ctccagccgt
      241 gcgcttcgtg acgttacccg tgctcatggc tgcgaatata atgccgccgc tgtaggcgag
      301 gtaaatgtgg ttaccaagat gaaggctacg aatgccgtga ttggtggtga gggcaacggt
      361 ggagtgatct atccggccag ccattacgga cgcgacgctt tggtaggtat cgccttgttc
      421 ctgactcatc tggcaaagaa gaagatgaag acgagcgagt tgaaggcttc ttatcctccg
      481 tattttatct ccaagcaaaa agtccagtta acgccggaga tcgacgtgga cgctatctta
      541 gcgaaagtaa aagagaagtt ctctcaatat gatattacgg atatcgacgg agtgaagatc
      601 gatttcccgg ataaatgggt tcatttgcgt aaaagcaata cggaaccgat catccgtatc
      661 tactctgagg cccatacgat ggaggaagcc gaggaattag gcggtcaatt aatacagatc
      721 atcaacgaga tgtgtaaata acaccctttc ggggtgtttt aaaatattgg gttcagtctt
      781 cagccgaggt aagctattta tgctctgttg atttgactga acccttttct tttggataat
      841 tctcggttcg tgtaatgaat aaactaataa aggtaatctt atttctaatt gtcgggatgg
      901 ttcaagcctt cgcatgggga gggctgagag gggacacgtt ggccaaggag ctggatgaag
      961 ctgtcttgaa tagatctttt tatctgcagc aacgggagca acggatcacg cagctaaagg
     1021 acatgtttct cttgagcaag atatcgttgt ggcaggaata tgagatcaac caccaattat
     1081 acgaggaatt caagaaaata caacaagact cggccatcta ttacataaag cggaatatgg
     1141 agatagcgtc atttatgaag gatacggcac gcatctatac ttcccgctta cgactggcta
     1201 cgctttatgc tttctccggg atgtaccgtg agtcggaaag tctgttgcga agcatagacc
     1261 gtgaattgct gtctaaagag cagaaacagg atttctatga ggcttattat tcgtttttct
     1321 cttattacag tacgaatctg gattcttttg aatataggaa acaacttgat ttatacaagg
     1381 attcgttatt gtctgtctta gatacggtct cttatcggta taagataaat ctggcgcaga
     1441 aatatctggc tcacggacag gcgaggtctg cggagaaggt gctcatccct ttattggaga
     1501 aagaggagcg gtataacccg aatttcgcga tgatcactta tctgctggga gatgtttatg
     1561 atatggatgg gcgtaccgat ctcgcccgag actattatac cttgtcggtt atcgccgata
     1621 tcaagagggc cttcttggat agtggttcta tccaaaagct ggcgttgaat tattgtgaaa
     1681 gtggtgatct atccaatgcc cttaaatatg cgcagctagc tatagaaggt gccgttactt
     1741 gcaatataca gttccgcatg aatgagatat ctaaattcta tcctatcatt aatgcttcct
     1801 atcagacacg ggaagctcag ggcaaaaggc aattgatgac ttatttcttg tcgatcagcc
     1861 tattgacgct ctttctgatc ctttctcttg cctatgtgta taggcagatg cggaagatct
     1921 cagcgatacg agaagagttg gttaatacca atgcccgttt ggtaaagttg aatagagaga
     1981 taagcgagac gaatgattta ttgcaagagc gaaatataca gctatcggag tcaaaccata
     2041 tcaaggagga atacatcgct catttcctcg atctctgctc cacctatatt aataaactgg
     2101 aggattacca gaaatcgcta cagaagaagg cgatgaataa acagttggac gagttattca
     2161 agatgctccg ttcgacccgt atggtggaga atgaggtgga agcgctttat gttaacttcg
     2221 atcgaatctt tcttggatta tatcctacgt ttgtcaagga cttcaacgct ttgttgcagc
     2281 ccgaggaacg tatcgttttg aaatcggagg atctgttgaa taaggaactt cgtatattcg
     2341 ccttgatgcg gttgggggtt acggacagcg taaggatagc cgcttttctt cgttgctcgt
     2401 tgagtacgat ctataactac cggaccaagg tacgtaataa ggcgttagtg cctcgtgatg
     2461 agtttgaagg ttgggtgatg aggatcggga ttaaccggaa tccgttataa tcaatctaca
     2521 ttttttagga tggtgatctt tattaactga tttgtattta ataggatagc ggatcatact
     2581 gtctacattt ttatatcaat cttctttttg cttcttattc ccggatacat ttgcggcata
     2641 acttttaaaa agagatgcca tgaagattaa attaatgatt gccgccgtga tcgcctgttt
     2701 ggtgttcacg ggatttacga aagagaacgt atccgatacg gtcgatcaca acgcatggaa
     2761 gacaaccggt gtcgtagtca tacaaaatga tgtccttacg ttggccggtt ccaacgcccg
     2821 tgctttgttg aacgatggca aaggctatac gaacttcgag ttagatatgg atgtacgtac
     2881 cacgaccggt ggcaaaggtt atattggtat ccatacggac gctacggatc gtaaaggata
     2941 ccgtatcgcc ttgaacaacg atcgggaaga tccggtttgg tggcggatga cgggtagctt
     3001 ggtgtcagtc cggaacctga cgaagagttt cgtgaaagag aacgaatggt tcaagatgaa
     3061 tatccgggta gaaggacggc ttatccgggt gcggattaat ggtgagactg tcgtagaata
     3121 tatagagcct tccaaacctt tccgtttgaa ggagaacgct aaagcattgt tatcccaagg
     3181 tactatctcg ctggtaggta cgggacgtgg aaatcttcag tttaagaata tctcgttaga
     3241 ggcgttcagc gcgaaaggaa tagacattcc cgctcaatgg gcgaatgccg tggatgagca
     3301 gacggacgag attattcgtt tgcatcaaga ggacttcccc gtgcttgatt atcatgttca
     3361 cttaaacggt ggattgacga aggaagtagc cgcacggcag tcacgctgga cgggtgttaa
     3421 ttatggcttg gctatcaatt gtggcatcgg cttctcgatc acgaacgata cggagttgta
     3481 taattatctg gataccatgc gtacccaacc ctttatcttg gctatgcaag cggaaggacg
     3541 tgagtgggta accacctttt cggaggcggc ccgcaacagc ttcgactatg tgtttaccga
     3601 tgccatgacg tttctggatc ataaggggcg gcgtacgcac ctatgggtaa acaaggaagt
     3661 gattatcgac gatgagcagg catatatgga tatgatgttg gaccgtatct gttctgtctt
     3721 ggaagagccg gtcgatatgt acgtgaattc ctgtttcctt ccctacgcga tgagtgaccg
     3781 atatgatatg ttttggacag aggagcgtat cgaccgtttc gtgaatgcct tggcaaaaag
     3841 tggaaaggct ttggagataa acgagcttta tcatattccg aataaagcga tcattcagaa
     3901 agcgaaagct gcgggtgtaa agttcacgtt cggttccaac aatatcacgc cggaggtagg
     3961 aacgctcgat tattgtatcc gtatgaaaaa ggaatgcggt ttgacggcgc aagatatgta
     4021 taaaccacac attaatatat aagattagtt ttaaggtctg aacaaacatt agatttaagg
     4081 tagaggtatt agtgctttag gcaaagattg ttaggtttcg aggtaagata catatggagt
     4141 tacagttata atataatagg tcgattacta taggacaaaa catcttattt actatatata
     4201 aagataatca tatatagtta cattccacaa accacggcgt gaatcgtaca gaccacagca
     4261 tggtttgtat aattcacgtc gtggtctgta cagttcacgc cgtggtttgt ggaatgtaac
     4321 agtatcttac gaagaatgaa caggctcttg aataactatt ctagctgaag tgtagcgttt
     4381 ttatcctata ggaaaatagc ggtgaattcc ttttcgaaat tcggggtgaa tgcgcctttc
     4441 cccagattct ccttgatctc ctcgatcggc cagaaacgtc ctccgtccag ttcctcggga
     4501 tcgggggtga tggggccatc gtaagtggtc cggaagctgt ttaccaattc cttctctatg
     4561 gaagactcga atatataacg tttgatgaag acaggcgtaa aatcagtaat gcccaattcc
     4621 tcacgaacct cacggcgcag ggcctcttcc acgctttctc cataatcaat atgcccacct
     4681 acggccgtgt cccattttcc cggttgtata tccttgttca tggaacgttt ttgtagatat
     4741 agatctccat ccttattaaa gatatgtaaa tggattacgg gatgtagcaa cttacttcca
     4801 ctatgacatt ccttgcgagt agcctttccg atcgtctcac cttcctcgtt taccagagga
     4861 aaccattctg ttctcatatt ttaaatagac tttaatttac tgataaccgt acctaactcc
     4921 tcatccgtta aattatttcc atacgtagcg taatccaagc ggaacgtaca tccattcttg
     4981 tattcggagc aaccataagc ggttttgccc cggaggatag agcctttgtg acagatgggg
     5041 caaacgggct tatccgttga tggaagctcc aattcaggag tagcctctgc tttctctttc
     5101 tctttcttgg cacgaggctt acgaggtttc ttttcctttt tctccttggg ttcgtctttg
     5161 ggagtttctt tagctgcttt agacgtatcc tcaatcgtaa tcgttcgccg ggtttggtcg
     5221 gaaaggacgt ttatgacgac ctcgtttacc atctgcttca actcatccag aaaagtacgg
     5281 gcctcataag tccctcgttc aatctggcgt agtttctttt cccaaagccc cgtcaactct
     5341 gcgcttttca gcagttcctc atggatcgtg ccgatcaatt ccgcgccggt agcggtggga
     5401 taaagattct tacgttcctt tcgtatataa ttacgcttaa ataaagtctc gatgatcgcc
     5461 gcacgggtag aaggacggcc gatgccgttt tcctttaagg catcccgcag ctcgtcatta
     5521 tccactaatt taccggcggt ttccatcgcc cgcaataaag tagcttccgt ataaggtttc
     5581 ggaggctggg tccaagtctc tttcaagatc ggtttatgcg ggccactttc tcctttcacg
     5641 aaatcgggca atacgccttc ttcctcggta ggttcagcct ccggatcttt ctgctcggct
     5701 ccgaatacga cacgccaacc cggtttgagg atttgctttc cggtcacctt gaattctacc
     5761 ttatccactt gacccaagac cgtagtggtc gatatctcgc aatccggata aaaggcggcg
     5821 ataaaacgac gggctaccaa atcgtacacc ttccgttccg tatccgtaag attgcgggcg
     5881 gggactccgg tagggatgat cgcatggtga tcggtaacct tcgagttatc aaacactttc
     5941 ttgcttttcg gcaatttctg attcatcaaa ggagcggtaa gctccgtata atccaccaac
     6001 cctttcaagg tattgggaac tttcggatag atatcatcac taaggaaagt cgtgtctaca
     6061 cgtgggtagg ttgtcacctt cttctcgtag agcgattgga tcaactttag cgtatcgtcc
     6121 gccgtaaacg cgaatttctt attacattcc acctgcaacg aggtcaagtc gaataggcgg
     6181 ggggcgaatt ccttcccttt cttctcggtg atactggtaa cagtaaaatc ctgttccttt
     6241 accttctcca gaaaagcctc gccttcctct ttcttcgtga acttaccttt cgtggcggag
     6301 aaagtcgtat tcctgtaaat ggtctttaat tcccaatagg gttccggctt gaaattgtcg
     6361 atctcggctt gccggtttac gatcaaggcg agcgtcgggg tttgcacacg gccgatcgat
     6421 aatacctgcc ggttctgccc gtagcgcaag gtataaaggc gggtggcgtt catccccagc
     6481 aaccagtcgc cgatggcacg ggatagcccg gcctcatata acttattgaa ttccgtctgt
     6541 tctttgagtt tttggaaacc ttcccggatc gcctcctccg taagcgagga gatccaaagg
     6601 cggtagaccg ggcatttaca acctgccttt tgcatgaccc agcgttggat cagctctccc
     6661 tcttggccgg catcaccgca gttaatgacc atctcggcat tttgcatcag gctctcgatt
     6721 accttgaatt gttgctcata cgtaggattc tcgattagtt tgataccgaa ccggggaggg
     6781 atcataggta gcgaccccag actccagcgt ttccagttct ccgcgtattc atgcggttct
     6841 ttcagggtac acaaatgccc gaatgtccaa gttacctgat atccgtttcc ttcgatatac
     6901 ccattcattc gttgggttgc ccctaatact tccgcgattt cccgggccac actcggcttt
     6961 tcggcgatac aaactttcat caatacatca tcctttctta aatgaacaga caaaaataca
     7021 tgattatttc cgaatgagca aagatgtttg ttatcgcgag tttataaagc tgtatgatgg
     7081 agttgctgat tttggttcaa tttgttttta cctttgggaa ttttgcatac atttgaacct
     7141 atgtaatcga agtgggagaa taagtcgaat ggcagacatt gattcagaga aagaaagaag
     7201 gcttgtggcg gacttgctag aaggggacga gtcggccttt tgtgaattat atgccctgta
     7261 taaggatcgc ttgatgtggt tttccttgaa attccttaaa tcccgggata tggcggaaga
     7321 tgtttttcag gatgctttcg cctctatttg gcagaatcgc cgtttcttga acccgaatgt
     7381 accttttggc ccgtatgtgt atacgatcgt gaaaaatcgg atcttaaacc tgttggcggg
     7441 actggatcgt gagttggagc tgagggataa gatacggtcc gcctcattgg atagcacgaa
     7501 cgagacggag gattcggtat tggatacgga tttaaacgca ttgttggata aggcgcttga
     7561 aacgttgagt ccacaacaaa aaagggtttt tgatatgagc cgtaaagata tgaaatccca
     7621 taaggagata gccgacagtt tgggtatctc ggtatatacg gtacaacaac atatctctac
     7681 ggccttgaaa gtgatccggg cgtttctggc taaatatgcg gagacttata tggagctact
     7741 gctctaaatg catctccctt attcatattc ccgataggca ccaaaccggg ctaaacgatc
     7801 ctcgccgagt tgttccggta caggttgcgg ggagaggccc aagccttcgt tgatctgttc
     7861 ccaaagtcct gtacgggtat aggtttgatg cactttctgg aaatgagtgg attgcaataa
     7921 atccttggct tcttgatatt gcttcctatc gatcagtagc tgtacctttc gctcggccac
     7981 ccattcgtca gaggatgcgt ttatcttatc cagccatttt tgccgttccg gtaaagcctc
     8041 ggttccaaat ttctttaata ctttatcccg ctcgataacc aactggggat gtaggttcag
     8101 ccacgaggtc tcggggatag cggcgtaggc atctctcgct ttttcccacg cctgccgacg
     8161 gacatatagc cttgccaata aagcttttgc cagatcgata tccgggatgg atagttgttc
     8221 gatcgcctcc tctacacgtt ctcttccagc caaccaagtc ccatagtgga attgccaata
     8281 atcccgttcc ggctggggag atatttggat cgcccaacga aaagcatcgt ccagatcttc
     8341 catgccggat ggagcccact gcccgtcttc cggatagggg gcggcgggaa gcatggactt
     8401 attcttatag gcatcggcta aggcgatcca gatggaagat tcattcttcc gggcccagtc
     8461 gaatagcggg atgcgatcga tcgggcgaag ccttaatgcc ggaaccttta aggaatagat
     8521 atccaaagga tgatctgtcg gtatccaata ttctacgtga ttctttttct cgccgggacg
     8581 caattcgagc ttgatagatt ggtcgctgat cgggccacct tggatttcta cgtaaggctg
     8641 ccggtcgggg gtactgagca tggaccattc cttgtcgccg gctacgccat aactccatag
     8701 cttgataccg ggcgtactgg attcgtcggc gatatgatag agcccgctgc ccaaggaggg
     8761 agtgtaggcc ccgaaagcat tcacgtcttt cgttttccag aagtagccgg tcatctcttt
     8821 gatatcccgt tcatgatggg ttccttccgt tttccagtcg atcgtgtcca acgtggaggc
     8881 atgggataat acggtcccgt tcgggaaatc gtattgggta tccggtgcgc aaggaagggc
     8941 ggcgttggac catgacatcc atggataggc ttgctttccc gggttgtagt aaacaaccct
     9001 ttgggtaagg cattcgtcct tatctcctaa ggaatattct acagaccatt gcataccgta
     9061 atgagattcc cgttctccgc atgttacata tgtgcggtct cccgtatgat cgatctgata
     9121 aagcaccggc tcattttgcg tgggagagtg ggagatcggg aaactgacct cgatcccccc
     9181 ggccacgaaa tagaaacggg gtaatatccg tgtgtatttg attacgtccg gcctgtacaa
     9241 gacctccttg ccgctctcct tgtgagtgag ggatattact ttcccgcaaa gatcggggca
     9301 gatgatagcc ttgactttct cgttctctag cgagatcatc cggtaccttt taggtaccgg
     9361 acgatttgag gtctcgctat aactcatata ggggtatacg ccattcgggt ccaaggcggt
     9421 cggcaacggg ccggtgggcg tcaatacgtg cgtcagctgt atctggtcga actcctcgca
     9481 aacaacacct gttgtctgcg agaaagctgt ccctacggct acgcttgcca tgagtgatag
     9541 gattaaacga tatgctttca tgtctttcct gttatataag cccattattt cgccaaaaga
     9601 tcggacagtt gacggatgat gaggttaccc ttacgtacat tcgccgagat cttgttctca
     9661 tcgaactctt tctctttcgg gaagatagac aaatgttggt ctagctgctt caataagcct
     9721 tgagcttgag cgttacccga ttgggtggtc agttcccgta agatacggac cttctcgaaa
     9781 tccacgatac cttctctcat tttctcgaag cggatgcaac ttttgcctcc cggatatacc
     9841 atgtagcaat cgcctgctgc ccaagagcca tgacgtgcgt cgcgatcggc atcttccggc
     9901 caagcgtcgt aagcccatcg caagaagccg tcataaccat acgccattac ataccaactg
     9961 atccaacgtc cctcgatagg aggtgagaac acgaagttgt tcgggatcgg cgggttacag
    10021 catacgtata cggtggacgt gcgtccggtg gcggcccgtg ctttttgctc ggcgatggta
    10081 ggttcctctc cgtaaaggaa agaataatcg tccagcagtc cgtccaattc cttatgccaa
    10141 ttgccggcgt aagtgatctt ccagcattta tcatggttac gcacgacatt gatagccgct
    10201 aaggtctctt ccatcggatt ctcgttgatt ccgatatagg tgatgtccaa ccagctttta
    10261 gcttccagat ggaacttgaa atccgtgagg aagatattcc acatcttctt gaattccttc
    10321 gagcttggcg tccagttgat ataagaataa tcgcccgtag cctcgtcctt atagcggtga
    10381 cggaatcccc aaggaatcgg ggtatagagg gtgattgcct cgtcgatgcc acattccatc
    10441 gctaattcta cgtactcgtc gaagattttg tagtcgaagg cccatgtgcc gtctgctttc
    10501 ttgatccact cgatcatgcc cccctcgatc atataagagt tatcggacca aggagaatgt
    10561 actccataag tcgtgatgta ggtaccacct gcgtcggcat aatgcttcaa atgctgctta
    10621 agaagcattt tatgttctgg tgaccacggt tccacgtgat tgtaccatgc cacggcccac
    10681 gggttctgcc ataggtccag acggtatttc cagtctttcg gataggggag caactggttt
    10741 tgcaccacga tttccagatt caatagttga ggagccttgc ctttcgcccg cacctccacc
    10801 tgtcctttat acgtgccggg agcggttcct ctcggcacat ccaccatcat ccataccgga
    10861 cgggtggttt gggaagggag atcgaagcgg tccagcgtct cgaaacggtc tggcatcaag
    10921 aagccggatt tgtagggaga ttccccgcag atggcttttt tctcggcata cggataattg
    10981 gacaatacgt aacgcaccaa ctcgaaggta atccggtctt ttgggatgat gtttccctcg
    11041 gcgctcctca agtcctgcgt agagacacgt acttgttcca acgcttctga cgaccatacc
    11101 aatatttggg cattcgctct ttcccccctc caaacggtcg tagagtagga agatgataaa
    11161 tcgttgtcat ggtttacggg tacttccttc cggaaataaa gtcggtcggt cgatccgaag
    11221 gcggaatgga tacccgcctg attgctccaa gcgggttcat tcacgcaaaa atcaaatgtt
    11281 aactccgggt catagtgatg actccgtaca gggacaaacg tggaatccat ctgccccgga
    11341 tacacttggc ctagactgat atgagaataa ataaaaaaac tagctactgc taaaaagtat
    11401 ttcttcatgc tataaaaatt taagataatt catatttaaa tgggattccc ctcccagata
    11461 ggtaggccct accttctcgt ataggtaggg cctaccctca tatatatagt cgcttattct
    11521 tggaaaaacc cttaccagcc cggattctgt tccaaggttc ctttcgacaa ttgtacctgt
    11581 tgcaaaggta tcggtgacag ccaatgcttc ggtgtctgga acttgcgggc ggatgcgggt
    11641 tgggcgatga taaagccatc gctatccacc tgtatatcct gcccgatcac caactccggg
    11701 aatttctgtt gatactccgt acccacgaat ttcacgccac ggatcgcaag gggaagaacc
    11761 gtttccgccg tgccccaacg acgtaggtcg tcccggcgat atccttcgaa tgccagttcc
    11821 acggttctct cacgccggat ctcttcctgc atattcagtc cgttcgtagc tacaaacgca
    11881 ttggtcaagc gaggcatatt cgcccggttt cgcaggtcat taatggtcag gtctaattgc
    11941 tcgtccgtga tctgtccgtt cttctcgtat aaagcctcgg c
//
LOCUS       DBMDTB010000111        11963 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_1619_length_11963_cov_11.655117, whole genome shotgun
            sequence.
ACCESSION   DBMDTB010000111 DBMDTB010000000
VERSION     DBMDTB010000111.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 11963)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 11963)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11963
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1619_length_11963_cov_11.655117"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..300)
                     /locus_tag="ACZPB4_14315"
     CDS             complement(<1..300)
                     /locus_tag="ACZPB4_14315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HIR1099424.1"
                     /translation="MKIRNILSVLFVGLLFTSCNSEEEVQRGNEDGRDISFSMTLTLG
                     EVTAMTKAGGDIAEGYTYSTEDEVKVNNVVVAIFNEANGTVGECLEYKSVAFDGGI"
     gene            complement(333..1436)
                     /locus_tag="ACZPB4_14320"
     CDS             complement(333..1436)
                     /locus_tag="ACZPB4_14320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099425.1"
                     /translation="MEIKTIISSICLLLLAVSCSMDDDALRDIEKGHSGSVVIEEGEV
                     ALSMKVSLFSLETKSLSGAGTLPASMDEAKIDNCTLIFFEGGQVNSIMEGLFVNSENY
                     IVKKKNGTEDDWAKVIVKVKKPSPYSVMVIANSSKSFAGCQSESDINDIIQDNKDALV
                     KVGKMNINFDSNFAGYATIREALEKPLEVGPVPLSQLTARIELAEFNVSGFQGASVQE
                     KITVTGVDLLNLNPESYTTNEQTHKNATYLQENKTCNVEVYDGVSELPSTYSFVENKN
                     VLSFYSFRNLAAAESDQVKIQVRFKVGNSEERTTRQFVINKEGNILHGVKSGYVYRLV
                     VNMTIIGDKVETELLCYTRDWLNNTISIPMEDN"
     gene            1963..2895
                     /locus_tag="ACZPB4_14325"
     CDS             1963..2895
                     /locus_tag="ACZPB4_14325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HIR1099426.1"
                     /translation="MKNKSSLVRFDWAIKRLLRQKSNFVVLEGLLSTLLGENVIIIRI
                     LESEGNKEDSEDKFNRIDVLAENSKGELVIIEVQNNRELDYFHRMLYGTSKAVTEYIH
                     EGEKYGTIKKIYSVNIIYFDLGQGKDYVYHGKTQFKGIHFDDILKLSTRQREQFVKQE
                     AGDIFPEYYVLRVNEFDELAKTPLDEWIYFLKTGEIDEHATAKGLPEAREKLRIDKLS
                     PSEKGQYYAHMEALRYQKSVIETGWIEGHADGRAEGRAEGIAEGKAEGRAEGIAEGQN
                     LEKRQIAANLKKEGLPIEIIANCTGLSPEEIANC"
     gene            complement(2919..3884)
                     /locus_tag="ACZPB4_14330"
     CDS             complement(2919..3884)
                     /locus_tag="ACZPB4_14330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HIR1099427.1"
                     /translation="MGNFFTSLFSSSKPAEATEDKAKNEQKNFDILKYDGVRAQKMGK
                     LVYAIKCFTEALNIQEDFETMSYLVSAYTMANDLGKAEDVLNRMVEMEPDHIATRLTR
                     VNLLFMLDKDAEVITDCLHVIELEPSNHVAYFMMAKAKKATNDVFGAIADLTRSISLK
                     EDFADAYLLRAEILLGLGQAKEALPDVEKAIEIVPEEESSYLLRGRIHMALGDIEAAN
                     SDFQQVLDLNPFNEDACILSGQLLIEQKKYDEAIAFFDEAIETNPSFAKAYSERGRAK
                     NLKGDKTGAFEDLKKSLELNPESEEAQKMNGQHSNFDNMYKGGIF"
     gene            4218..4514
                     /locus_tag="ACZPB4_14335"
     CDS             4218..4514
                     /locus_tag="ACZPB4_14335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OadG family protein"
                     /protein_id="HIR1099428.1"
                     /translation="MENIETGLLLMVVGMTTVFAILLIVINLGKGLIVLVNKYAPEEI
                     IAKKPVAAAVRVQTATPTQTTAIGSLSGQETAAIVSAISAVTRGQGKVIKIEKV"
     gene            4533..6458
                     /locus_tag="ACZPB4_14340"
     CDS             4533..6458
                     /locus_tag="ACZPB4_14340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin/lipoyl-containing protein"
                     /protein_id="HIR1099429.1"
                     /translation="MKREIKFSLVFRDMWQSAGKYVPTVDQLTRVAPAIIEMGCFARV
                     ETNGGGFEQVNLLFGENPNKAVREWTKPFHAAGIQTHMLDRALNGLRMSPVPDDVRQL
                     FYKVKKAQGTDIARTFCGLNDVRNIAPSIKYAKEAGMISQCSLCITHSPVHTVEYYTK
                     MAFELIELGADEICIKDMAGIGRPYTLGRIVANIKEKYPEIPIQYHSHAGPGFNVASI
                     MEVCNAGCDYIDVGMEPLSWGTGHADLLTVQAMLKDAGYKVPEINMEAYMKVRALVQE
                     FMDDFLGLYISPKNRLMNSLLIGPGLPGGMMGSLMADLEKNLETINKSNIKNNKPLMS
                     QDQLLIKLFDEVAYVWPRVGYPPLVTPFSQYVKNLALMNVMQMEKGKARWSMIADDIW
                     DMILGKAGRLPGPLAPEIVEKAKAEGRQFFEGNPQDNYPDALDKYRKLMNEKQWEVGE
                     DEEELFEYAMHPAQYEAYRSGKAKVEFKADVAKRKAEKANAGKPTVPATPAAPAPAPA
                     ATLAMPTTPQVMTVDVNGQAYRVTVAFGDTNSTTPEVKPTAAPAPTAPETTNAPAGAG
                     KEVLSPLEGKFFLIKNASDTPVKVGDVVKEGDVLCYVEAMKTYNAVRAEFGGTITAIC
                     LSSGDAVSEDDVLMTIQ"
     gene            6458..7693
                     /locus_tag="ACZPB4_14345"
     CDS             6458..7693
                     /locus_tag="ACZPB4_14345"
                     /EC_number="7.2.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium ion-translocating decarboxylase subunit
                     beta"
                     /protein_id="HIR1099430.1"
                     /translation="MNEIFQNLYEMTAFSNIIAEPQFLIMYAIAFVLLYLGIKKQYEP
                     LLLVPIAFGVLLANFPGGDMGVIQADENGLINVHGVMRNIWEMPLHDIAHELGLMNFI
                     YYMLIKTGFLPPIIFMGVGALTDFGPMLRNLRLSIFGAAAQLGIFTVLLVAILMGFTP
                     KEAASLGIIGGADGPTAIFTTIKLAPHLLGPIAIAAYSYMALVPVIIPLVVKLLCSKK
                     ELRINMKEQEKKYPSNMEIKNLRVLKIIFPIVVTTVVALFVPSSVPLIGMLMFGNLVK
                     EIGTNTFRLFDAASNSIMNAATIFLGLSVGATMTTEAFLNLTTIGIVIGGFLAFALSI
                     AGGIFFVKIFNLFTKKKINPLIGATGLSAVPMASRVANEIALQYDPKNHVLQYCMASN
                     ISGVIGSAVAAGVLISFLG"
     gene            7910..9763
                     /locus_tag="ACZPB4_14350"
     CDS             7910..9763
                     /locus_tag="ACZPB4_14350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF349 domain-containing protein"
                     /protein_id="HIR1099431.1"
                     /translation="MKDTLETNLPEEAGKLEETKKPVETPEIDATADVEANDTAEADA
                     AIAAGKLTKEEILAKLTELVETSVETSRGEVEALKQAYYKIRRNEVEELKKVFIADGG
                     EEKDFTAPADETENKIKDLLTSYKEKRAAILAEEERVKAANYALKLQLIDQLKELCES
                     QDDFNKLYNSFKDIQQRWKEVKAVPQEHVNELWKNYQIYTEKFYDIIKINNQFRDYDF
                     KKNLELKTALCETVEKLGNEPDVISAFHQLQKLHQQWREIGPVAKELREDLWARFKAA
                     STVINKRHQEHFEKLKAKEQENLDAKTVICEQIEAIDFSALKSFKDWEEKNKEVIGLQ
                     EKWKTIGFAPKKYNVKIFERFRAACDVYFEKKSEFYKAIKSDMEKNLDAKRALCEKAE
                     ALKDSTDWKDTTDKMIALQKEWKTIGPVARKHSDAVWKRFISACDYFFEQKNKNVVSQ
                     KSIEQTNLAAKKELIAKIKGMDESLGHDEAITTLKSYMAEWNTIGFVPFKEKDKIYKE
                     YHEAVDQQFDRLKVDQNDRKMQSFRNNLNEMTSGERGKGRLFSERDKLMRMYERMKNE
                     LQTYENNIGFLSISSKGGGGLLKEMERKIEKLKEDMALTVKKIDAIDENLE"
     gene            9827..11035
                     /locus_tag="ACZPB4_14355"
     CDS             9827..11035
                     /locus_tag="ACZPB4_14355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099432.1"
                     /translation="MSRIHYFNPGHETAVLLGTQNYTAPTNVRKMQKDLALLPVWYAE
                     EDDFVYLEDSKATPPFFAHLPKDLHPAPIPVTKAMLVKNAPYLSPMDAAPWGLSPHSL
                     HLFEQLRDKAKVRLSVPTWKEDYFRLTGRQTAAECLEKIQALLPDLPIPVAPRFCTKI
                     REVERYMLLCNAPFVLKTPYSSSGRGLLWVEKRKPDTKTKNWIEGAFNKQGMISIESG
                     LDKVQDFAMEFYSDGQGTVRYEGLSVFNTEERGSYTGNILEEQSTMLSRITRFTGEET
                     YSRIQEAVRSVLQEVYGSTYAGCIGVDMLVYRQKDGSFAIHPCIEINMRYTMGMVALR
                     LFQHYVAPRAVGDYRVSYEKEAGEALEKHRLMSETYPLRFANGRIQEGYLSLCPVTKD
                     THYRAYLLLI"
     gene            11101..>11963
                     /locus_tag="ACZPB4_14360"
     CDS             11101..>11963
                     /locus_tag="ACZPB4_14360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HIR1099433.1"
                     /translation="MKRLSILAVFMLISVITFAQQALWGSQNIISPEIHPDNTVTFRF
                     MAPKAIKVQVTGDFLPTQKMETQFGLVDVPGTVDLKEGKEGVWEYTTPEPLPSELYSY
                     SFIVDGLKTTDPNNVYLNRDVASVTNIFIIKGGQGDLYSVNDVPHGTVARRWYESPTL
                     GKTRRITVYTPAGYETSGKKYPVFYLLHGMGGDEEAWIALGRTAQILDNLIAQGKAKP
                     MIVVMTNGNADQEAAPGESSLGLVKPNMQLPKTMEGSMESSFPDVIKFIESNYRVEKK
                     KSSRAIAGLSMG"
BASE COUNT         3478 a         2709 c         2730 g         3046 t
ORIGIN      
        1 aattcccccg tcaaacgcta cagacttgta ctccaagcac tcacccacag ttccattcgc
       61 ctcattaaat atagcgacca caacattatt cacttttacc tcatcctccg tcgaatatgt
      121 atacccttca gcgatatccc ctccagcttt cgtcatcgct gtcacttctc ccaaagtaag
      181 agtcatagag aatgagatat cccgcccgtc ctcatttcct cgctgaactt cttcttccga
      241 gttacagctc gtgaaaagca gtccgacaaa cagcactgat aatatattcc ttattttcat
      301 aatcttgtat ttttatttta cccgtttaca ctttaattat cttccatagg aatggatatg
      361 gtattattca accaatctct tgtatagcaa agtagttctg tctcgacctt atctccaata
      421 atagtcatat tgacaaccaa gcgataaaca tatccggatt ttacaccatg caaaatattc
      481 ccctccttat tgatcacaaa ctgccttgtc gttctttcct cgctatttcc gaccttaaac
      541 cggacttgta ttttcacttg atcactttct gccgccgcca gattccggaa cgagtaaaaa
      601 gacaatacat ttttattctc tacaaaagaa taagttgacg gaagctccga tactccatca
      661 tatacctcca cattacacgt cttattctcc tgcaaataag tcgcattttt atgagtttgc
      721 tcatttgtcg tataactctc aggattcaag ttcaacagat ccacacctgt aacagtaatc
      781 ttctcttgaa cagatgctcc ttgaaaacca gaaacattaa attccgcaag ttctatacga
      841 gcggttagct gagaaagagg gactggacca acttctaaag gtttttccaa tgcttcccta
      901 attgtcgcat aaccggcaaa gttggaatca aaattgatat tcattttccc tactttaact
      961 aaagcatcct tattatcctg tattatatcg tttatatcac tttccgattg acaacccgca
     1021 aacgatttag agctattagc gattaccatt acggagtaag ggctaggctt tttcactttc
     1081 acgattactt ttgcccagtc atcttccgtg ccgtttttct ttttaacgat ataattctcg
     1141 ctatttacaa acagcccttc cattatcgaa ttgacttgcc caccctcaaa aaaaatcaat
     1201 gtacaattat caatctttgc ctcgtccatg gaagcaggca atgtccctgc gccagacaag
     1261 gattttgtct ccaaagaaaa aagagaaact ttcatagaaa gggcaacctc tccctcctct
     1321 atcacaacac tccccgaatg tcctttctct atatccctca gcgcatcatc atccattgag
     1381 cacgagaccg ccagcagtaa caagcagata cttgagatta tcgtctttat ttccatattc
     1441 ttatatttat tcgttcaacc tccttattct tgataaaaga cattaagatg gattgagttc
     1501 agataggact aagggcggtg agttacgtag gaaaataggc taaataagga aagatcaacc
     1561 ctctccatta ttgaatggca aattgagctg atctgaaaat aatgtctacc aaaataataa
     1621 aattggatag aatatgcaat ctgacaagta tttggaatgg aaggaaaggt attagtccta
     1681 tctgtactag ataccggaaa tttgtaagtt aggcttttta cactggcaaa attaaatgga
     1741 tacattaatg aatggaatag gcggaacttt caactttaag gggtaaaact agcaatttaa
     1801 ggcttgttga aataaacgat agagaatcct atcatttcga tagagatacc catgctgcca
     1861 gagaaacatt ataagtcatg gttgcttttt tatgaatagg aacaaagata atcgtttaat
     1921 tcattatctt tgtggaagta taaacaaata aacaagataa ctatgaaaaa taaatcatcg
     1981 ttagtacgtt tcgattgggc gatcaaacgt ttacttcgcc aaaagtccaa ttttgtagtc
     2041 ctcgaaggtc ttttatccac ccttctcggg gaaaacgtga ttattatccg catcctagaa
     2101 agcgaaggta acaaagagga tagcgaggac aagttcaacc gcatagacgt attggcagaa
     2161 aacagtaaag gcgagctggt aatcatcgag gtacaaaaca accgggagct agattatttt
     2221 caccgtatgc tatatggcac atccaaggca gtcaccgagt atattcatga gggagagaaa
     2281 tacggtacta tcaagaaaat ctactccgta aacattatct atttcgatct tgggcaggga
     2341 aaagattacg tatatcacgg gaagacccaa ttcaaaggta ttcattttga tgatatattg
     2401 aaactatcca cccgccaacg ggaacaattc gtcaaacaag aagctggcga tatttttcct
     2461 gaatattacg tattacgtgt caacgagttt gacgaactgg cgaaaacacc cctcgacgaa
     2521 tggatctatt tcctaaaaac aggagaaata gatgaacatg ccaccgccaa aggattgcca
     2581 gaagcacggg agaagttacg gatcgataaa ctcagccctt ccgagaaggg ccaatactac
     2641 gcccacatgg aagcccttcg atatcaaaag agcgtcatcg agaccggatg gatagaaggg
     2701 catgcggatg gacgagcgga aggcagagca gaaggcatcg cggagggtaa agcggaaggt
     2761 agagcggagg gtatcgcaga aggacagaac ctagagaaac gtcaaattgc cgccaacttg
     2821 aaaaaggaag ggcttcccat cgagatcata gcgaattgca cagggctttc tccggaagaa
     2881 atagcgaatt gctaatacct atttatataa agggggaatc aaaagattcc ccctttatac
     2941 atattatcga aattcgaatg ctgtccgttc atcttctggg cctcctcgct ttctggattc
     3001 agttccaaag atttcttcaa gtcctcgaac gcaccggtct tatcaccttt cagattcttg
     3061 gctcgcccac gctcactata agccttggca aaagacggat tcgtctcgat cgcctcgtcg
     3121 aagaaagcga tcgcctcgtc atatttcttt tgctcgatca gtaactgacc agataagata
     3181 caagcgtcct cattaaacgg atttagatct aggacctgct ggaaatcaga attcgcggcc
     3241 tcgatatccc ctaaagccat atgaatacgt cctctcaata aataagaact ttcctcctcc
     3301 ggcacgatct cgatcgcttt ctccacatcg ggcagcgcct ctttagcttg tcccagtcct
     3361 aaaagaatct ccgcacgcaa taaataagca tcggcgaaat cctccttcaa ggagatcgat
     3421 ctcgtcaggt cggcgatagc gccaaatacg tcattcgtcg ctttcttcgc ttttgccatc
     3481 atgaaataag cgacatgatt agaaggctct agctcgatca cgtgcaaaca atcggttatg
     3541 acctccgcat ccttatccaa cataaacaat aagttaacgc gagtcaagcg ggtagcgata
     3601 tgatccggct ccatctcaac catccggttc aacacgtcct cggctttccc tagatcgttc
     3661 gccatcgtat aagcggagac gagatagctc atcgtctcaa aatcctcctg tatattcagt
     3721 gcctccgtaa agcatttgat cgcataaaca agttttccca tcttctgggc acgtacgccg
     3781 tcgtatttca agatatcaaa gttcttctgc tcgttcttcg ccttatcctc cgtcgcctcg
     3841 gccggtttgg aagaagagaa taaagatgta aagaaatttc ccatggtctt attccttaat
     3901 tattatagtt ctacattatt agaattccac cgcaaagtta cggtaatata tttgaatttt
     3961 cagccgtaca agcgccggaa aaaacacgta cgtgtttttg gaaaaagtcg tacatgtttt
     4021 tcggaaaaca cgtacatgtt ttttcaagct gacaatcatt caccgaaaag gccgtttcgc
     4081 ttatttattt tcattttttt aattaaaatg taacagatcg ttttccagta ttttataatt
     4141 ttgcgattgt ttttaatttg gctgaaagtt gctcaatcct ttgtagaaac cttttaagct
     4201 agccacaaat atagaatatg gagaatatag agacaggact tttgttaatg gtagttggaa
     4261 tgaccaccgt atttgctatc cttttgatcg ttatcaatct gggaaaagga cttatcgtct
     4321 tggtgaataa atacgcaccg gaagagatca tagcgaagaa accagtagcg gcagccgttc
     4381 gggtacaaac ggccactcca acgcaaacca ccgcaatcgg cagtctttcc ggacaggaga
     4441 cagccgccat cgtatcggca atcagcgccg tgacccgtgg acaggggaaa gttatcaaaa
     4501 ttgagaaagt ataaataata catattaata tcatgaaaag agaaatcaaa ttcagtttgg
     4561 tcttcagaga catgtggcaa tctgccggaa agtatgtccc gaccgtagac caactaacca
     4621 gagtcgctcc ggcaattatc gagatgggct gtttcgcccg ggtggaaacg aatggcggag
     4681 gatttgaaca agtcaactta ttattcggag agaatcctaa taaagcggtc cgtgaatgga
     4741 caaaaccttt ccatgcggca ggtatccaga cgcatatgtt ggaccgcgcg ttgaacggcc
     4801 ttcgcatgag cccggtaccc gacgatgtac gtcagctatt ttataaggta aagaaagcgc
     4861 agggaacgga tatcgcccgc acgttctgcg gtttgaacga cgtacggaat atcgccccat
     4921 ctattaaata cgcgaaagag gccggtatga tctcacaatg ctccttgtgt atcacgcatt
     4981 ctccggtaca tacggttgag tattatacca agatggcatt cgagttgatc gagctcggag
     5041 cggatgagat ttgtatcaag gatatggccg gtatcggacg tccgtacaca ttaggccgta
     5101 tcgtagccaa tatcaaggaa aaatatccag agatcccgat ccaatatcat agccatgccg
     5161 gtcccggctt taacgtagct tccatcatgg aggtttgtaa cgcgggttgc gactatatcg
     5221 acgtaggtat ggagccgctt tcttggggta caggacatgc ggacttgctg accgtacagg
     5281 cgatgttgaa ggacgccggt tataaggtgc ccgagatcaa tatggaggct tatatgaagg
     5341 ttcgtgcctt ggttcaagaa ttcatggatg atttcttggg attgtatatc agcccgaaga
     5401 accggttgat gaattccttg ctgatcggac cgggacttcc gggcggtatg atgggtagct
     5461 tgatggcgga ccttgagaag aacctagaga cgatcaacaa gagcaatata aagaacaaca
     5521 aaccgctgat gtctcaagac cagttattga tcaagttgtt cgacgaggta gcttacgtat
     5581 ggccacgtgt cggttatcct ccattggtaa ctccattcag ccaatacgtg aagaacctag
     5641 ctttgatgaa cgtcatgcag atggagaagg ggaaagcccg ctggagcatg atcgccgacg
     5701 atatctggga tatgatcctc ggaaaggccg gacgtcttcc gggcccgttg gctcccgaga
     5761 tcgtcgagaa ggcgaaggcc gaaggccgcc agttcttcga gggcaatcct caagacaatt
     5821 atccggacgc attggataag tatcgaaagt tgatgaacga gaagcaatgg gaagttggcg
     5881 aggatgagga agagctcttc gaatacgcca tgcaccccgc tcaatacgag gcatatcgct
     5941 ccggaaaggc caaggttgag tttaaggcag acgtggcaaa acgtaaggca gagaaagcga
     6001 acgccggtaa accgacggta cccgccactc cagccgcacc ggctccggca ccagccgcta
     6061 cattagcgat gccaacgact ccgcaagtca tgaccgtaga tgtaaacggg caagcttacc
     6121 gtgtgaccgt cgcttttggt gataccaaca gcacgactcc ggaagttaaa ccgacagcgg
     6181 ctcccgcccc aacagccccg gagacaacaa atgctcccgc aggtgctgga aaagaggtgc
     6241 tttctccgct ggaaggtaaa ttcttcctta taaagaacgc ttccgataca ccggtgaagg
     6301 taggcgacgt agtgaaagaa ggtgatgtcc tttgctacgt ggaggccatg aaaacataca
     6361 atgccgtacg tgccgagttc gggggaacga tcacggcgat ctgcctgtct tccggtgatg
     6421 ccgtatctga ggatgatgta ttaatgacga ttcaataatg aacgagatat ttcaaaactt
     6481 atatgagatg actgcgttca gcaatatcat tgctgaaccg cagttcttga tcatgtatgc
     6541 catagcgttc gtattgctct acctcggtat caagaaacaa tacgagccgc tattgctcgt
     6601 gcctatcgcg ttcggcgtat tgctcgccaa tttccccgga ggcgatatgg gagtgattca
     6661 agcggatgag aatgggttga ttaatgtaca cggcgtgatg agaaacatct gggaaatgcc
     6721 gctgcatgac atcgcgcacg agcttggctt gatgaacttc atctattata tgttgatcaa
     6781 gacgggcttc ttgccgccga ttatcttcat gggtgtcggt gcgttgaccg acttcggccc
     6841 gatgctccgc aaccttcgcc tatccatttt cggcgccgcg gcccaattgg gaatcttcac
     6901 ggtgcttttg gtagcgatct tgatgggatt cacaccgaaa gaggcagcgt ctttaggtat
     6961 tatcggtggc gccgatggcc cgacggctat cttcacgacc attaaattgg ctccgcattt
     7021 gctaggcccg atcgctatcg ccgcttattc ttacatggct ttggtaccgg ttatcatccc
     7081 gttggtcgtt aagctactgt gttctaagaa agaattacgg atcaacatga aggaacaaga
     7141 gaagaaatac ccttctaaca tggagatcaa aaatttgcgt gtattgaaga ttatcttccc
     7201 gatcgtggta actaccgtag tcgccttgtt tgttcccagc tccgttcctt tgatcggtat
     7261 gttgatgttc ggtaatcttg taaaagagat cggaaccaat acgttccgtc tgttcgatgc
     7321 cgcttccaac agcatcatga acgcagccac gatcttcctc ggattatccg tcggggcgac
     7381 catgaccacg gaagcgttct tgaacctgac aacaatcggt atcgtaatcg gcggtttctt
     7441 ggcattcgcc ttgtctatcg ccgggggtat cttcttcgtt aagattttca atttgttcac
     7501 taagaagaaa atcaatccgc ttatcggagc cacgggttta agtgctgtac ccatggcctc
     7561 tcgtgtggcg aatgagatcg cgttacaata tgatccgaag aaccatgtct tgcaatattg
     7621 catggctagt aatatctcgg gggtgatcgg ctcagcggta gctgccggcg tgttgatttc
     7681 cttcttggga taaataagat taaatagtat gagtagatgg tgggagacgg ggcatgcccc
     7741 gtctctacaa ccggaatcag gagaaatcgg ccaaccttaa catctattag tatccaaaat
     7801 gactttttag ataaataatt tcctcgaaat gctgtaatcc aaaaatattt agtttaattt
     7861 gtgacttgat ataggaatgt atttatcctt ttcttaaaag cgattgtata tgaaggacac
     7921 tcttgagact aatttgccgg aagaagccgg gaaattggaa gaaactaaaa aaccggttga
     7981 gacgccggaa atcgatgcta ccgcagacgt tgaagccaac gacacagcgg aggcggacgc
     8041 tgctattgcc gcaggtaaat taaccaaaga agaaattctc gctaagttaa ccgaacttgt
     8101 tgagacttcc gtagagactt cccgtggaga agtagaggct ttgaaacagg cttactacaa
     8161 gatccgtcgt aacgaggtgg aagagcttaa gaaagtattc atcgctgatg gtggcgaaga
     8221 aaaggatttt acagcccccg ctgacgaaac cgagaacaag atcaaggatt tgctcacctc
     8281 ttataaagag aaaagagccg ctatcctcgc cgaggaagag cgtgtaaagg ccgctaacta
     8341 cgctttgaaa ttgcagttga tcgaccagtt gaaagagctt tgcgaaagcc aagatgattt
     8401 caataaatta tacaactctt tcaaggacat ccaacaaaga tggaaagagg tgaaggccgt
     8461 tccccaagag cacgtgaacg agctttggaa gaactatcag atctacaccg agaaattcta
     8521 tgatattatc aagataaaca atcagttccg tgattacgac ttcaagaaga atctggaatt
     8581 gaagaccgcc ttgtgcgaaa ccgtagaaaa actaggtaac gagccggatg ttatctccgc
     8641 tttccaccag cttcagaagc tgcaccagca atggcgtgag atcgggccgg tagcgaaaga
     8701 gttacgtgag gacttatggg ctcgcttcaa agctgcctca accgtgatca ataagcgtca
     8761 ccaagagcac ttcgagaaac tgaaagcgaa agagcaggag aatctggatg cgaagaccgt
     8821 gatttgcgaa caaatcgagg cgattgattt cagcgcgttg aaatcgttta aggattggga
     8881 agaaaagaat aaggaggtaa tcggcttgca agagaaatgg aagacgattg gtttcgctcc
     8941 gaaaaaatat aacgtaaaga tattcgaacg tttccgtgcc gcttgcgatg tctacttcga
     9001 gaagaagagc gagttctaca aggcgatcaa gagcgatatg gagaaaaacc tcgacgctaa
     9061 acgtgcgtta tgcgagaaag ccgaggcttt gaaggatagt acggactgga aggatacgac
     9121 ggataagatg atcgctttgc agaaagaatg gaagacgatc ggaccggtag cccgtaagca
     9181 ttccgacgct gtctggaaac gttttatctc ggcttgtgat tatttcttcg agcaaaagaa
     9241 taagaacgtt gtttcccaaa agagcataga gcagaccaac ttggccgcta agaaagagtt
     9301 gatcgctaag attaagggca tggacgagag ccttggacat gatgaggcta tcacgacctt
     9361 gaagtcttat atggcggaat ggaacacgat cggtttcgta ccgttcaagg agaaagataa
     9421 gatctacaag gaatatcacg aggcggttga ccaacaattc gatcgcttga aggtagacca
     9481 gaacgatcgc aagatgcagt cgttccgcaa caacctaaac gagatgacca gcggcgaaag
     9541 aggtaaaggc cgtttgttca gcgagcgtga taagttgatg cgtatgtacg agcgcatgaa
     9601 gaacgagctt cagacttacg agaacaacat cggcttccta agcatttcct ccaagggcgg
     9661 cggcggttta ctgaaagaaa tggaacgcaa gatcgaaaaa ctgaaagagg atatggcttt
     9721 aacagtcaag aagatcgatg ccatcgacga gaatctggaa taacaatctc ataaacccga
     9781 gcaaagccgt cctttaaaaa gacggctttg ttgtttttac gcttttatgt cacggataca
     9841 ttatttcaat cccggccacg agacggccgt acttttaggg acacagaact acacggcacc
     9901 gacaaatgtc cgtaaaatgc aaaaagactt ggcgctgctg ccggtttggt atgcggaaga
     9961 ggatgatttt gtctatctgg aagatagtaa ggcaacccct ccgtttttcg cccatttgcc
    10021 caaagaccta cacccggctc ctatacctgt aacaaaagcg atgctggtga aaaacgctcc
    10081 ctacctctct cctatggacg cggccccgtg gggactttcc ccgcatagtc ttcatttatt
    10141 cgagcagttg agggacaagg caaaagtccg gctatccgtc ccgacttgga aagaggatta
    10201 ttttcgcctt accggtaggc aaacggcggc ggaatgtctg gaaaagatac aggccctcct
    10261 acccgatctc cctattccgg tagcgcctcg tttctgcacg aaaatccggg aggtggagag
    10321 atacatgctc ttatgcaacg ctcccttcgt attaaaaaca ccctattcct cttccggacg
    10381 gggattgcta tgggtagaga aacgaaaacc ggatacaaaa acgaaaaact ggatagaggg
    10441 cgcattcaac aaacaaggaa tgatcagcat cgaaagcgga ttagacaaag tacaggattt
    10501 cgccatggaa ttttattccg acgggcaagg tactgtccgt tacgagggat tatccgtttt
    10561 caataccgag gagcgaggct cctatacagg caacatccta gaggaacaat ccaccatgct
    10621 ctctcgcatc acccgattca cgggcgaaga aacctattcc cgcatccaag aggcggtacg
    10681 ctctgtatta caagaagtgt acggatctac ttacgcgggc tgtataggtg tggatatgct
    10741 ggtctataga caaaaggatg gatctttcgc tattcatccc tgcattgaga tcaatatgcg
    10801 gtacacgatg ggaatggtcg ctttacgtct attccagcat tatgtagcgc ctagggctgt
    10861 tggcgattac cgggtttctt acgagaagga agccggagaa gctctcgaga aacaccgcct
    10921 catgtctgag acttatccac ttcgctttgc gaatggaagg attcaagaag gctacctctc
    10981 attatgcccc gtcacgaaag acacacatta tcgagcctat ttattgctca tataacagat
    11041 tattcattac atttgtaaaa atctttagac ctcagtaata ccattaataa atttatcatt
    11101 atgaaaagat tatcaatctt ggccgtattc atgctgatca gcgtgatcac gttcgcccaa
    11161 caagcccttt ggggtagtca gaacatcatc tctccggaga ttcatccgga taacaccgta
    11221 accttccggt tcatggcacc caaagcgatc aaggtgcagg taacaggaga tttccttccc
    11281 acacagaaga tggagactca gttcggttta gtggatgtac ccggtaccgt tgatttaaag
    11341 gaaggtaaag aaggcgtttg ggaatatacc acaccggaac ctcttccctc cgaattatat
    11401 agctattcct ttattgtcga tggattaaag actacagatc ctaataatgt ctatctgaac
    11461 cgtgacgtgg catccgttac gaatatcttt atcatcaagg gtggacaggg cgatttatac
    11521 agcgttaatg atgttcctca cggaacggtc gctcgccgtt ggtatgagag cccgacattg
    11581 ggaaagaccc gccgtattac cgtttatacg ccggctggct atgagacaag tggcaaaaaa
    11641 tatccggtat tctacctctt acatggcatg ggtggcgacg aggaagcttg gatcgcctta
    11701 ggacgtacgg cccagatctt agacaatttg atcgcccaag gtaaggcaaa accgatgatc
    11761 gtggttatga caaacggaaa cgcggatcaa gaggccgctc cgggagaatc cagcctaggt
    11821 ttagttaagc cgaatatgca actacctaaa accatggagg gtagcatgga aagcagcttc
    11881 ccggatgtca ttaagtttat cgagagcaat taccgtgtgg aaaaaaagaa atccagccgt
    11941 gcgatagccg gactttccat ggg
//
LOCUS       DBMDTB010000112        11689 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_1651_length_11689_cov_10.018726, whole genome shotgun
            sequence.
ACCESSION   DBMDTB010000112 DBMDTB010000000
VERSION     DBMDTB010000112.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 11689)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 11689)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11689
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1651_length_11689_cov_10.018726"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..975
                     /locus_tag="ACZPB4_14365"
     CDS             <1..975
                     /locus_tag="ACZPB4_14365"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008771971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016628 - oxidoreductase activity, acting
                     on the CH-CH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HIR1099434.1"
                     /translation="RTVGKVLKRGDYVVYESTVYPGCTEEDCIPILEEVSGLRVGEDF
                     KVGYSPERINPGDKVHTLVNTVKIVSGCDAEALETISEVYKLVVQAGLHRAPSIKVAE
                     AAKIIENTQRDVNIALMNELSIIFDRMGVNTFDVLKAAGTKWNFLPFSPGLVGGHCIG
                     VDPYYLVHKAKELQYHTKMINSGRYVNDSMGRYIGKKVVKKIISQGKNILGAHVLVMG
                     MTFKENVSDIRNSKVADIINEFKDFGAEVDVMDPFASPLEVLQEYGIRLVERPGKKYD
                     AVVVAVAHTTYLKLDESYFMSITNEHAVLADVKGVYRGSIHQMIYWSL"
     gene            complement(1187..2743)
                     /locus_tag="ACZPB4_14370"
     CDS             complement(1187..2743)
                     /locus_tag="ACZPB4_14370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="STN and carboxypeptidase regulatory-like
                     domain-containing protein"
                     /protein_id="HIR1099435.1"
                     /translation="MDDFRTLRQLVVGWLLLLVALIPMNAQNGNVLGQVIRLPKSKGN
                     IYQLLGLVTERSGYLFIYDSKIIDNEQTTSIKGGDYTIQEAIYAITGNKNLAIRAIEN
                     HLLLYMPESLSAPKSVSVTPDSIQTYFSIEGSLQDQYTHEPIAFGSVGIGEAAIGTIT
                     NQNGEFRLKLPDSLRLSKVRFSHIGYLPQEIDSRELIDKHTVLSLEPKVISIQEVIVR
                     LTNPKRLLQEMLDKRRSNYSQHPIYLTTFYREGVERKKGLVGLTEAVFKVYKASYHSN
                     ALADQVKLLKMRRISNEQEKDTLITKMKSGIYSCLVLDLMKQLPEFLDPSPDSPYTYA
                     HTDITVVDDRLANVISFEQRKSINEPLYRGQIYIDMENNALLRVDFEVNPQYIEQAAG
                     MFVERKSRNLRITPQKVAYTVSYKQWNGTYYINHIRGDLHFKIKKRRQLFNTNILHTW
                     FEMVTCKIDTTNVNRFSRIESLPTRTVFSDTHFNYDEGFWGDFNVILPEDKLNEAISR
                     ITSKIEETNY"
     gene            complement(2722..3573)
                     /locus_tag="ACZPB4_14375"
     CDS             complement(2722..3573)
                     /locus_tag="ACZPB4_14375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecR family protein"
                     /protein_id="HIR1099436.1"
                     /translation="MNQIEKNKLKTDQAWEQLYTRLEQDGLLDKPISGTQIPYRIGLM
                     KWAAAIIILCVSVATAIFLGQERTPETTLLTLHNNEASTTLVTTLEDGSIVYLADNSQ
                     LSYPEHFQREKREVSLLGNALFDVSGNKERPFLIETEQARIEVLGTSFNIKSSDKSAF
                     ELAVRRGLVKVTLKKNGEQTLVKAGQTVSLFSNRLQVVPTQDNEQFSDYTRRIQFKDE
                     RLGDILHVINLEYPKMPLKTTADLENRRLTVSFYNNSPATMAELICAALKLKCTQQNN
                     IWMISEP"
     gene            complement(3579..4118)
                     /locus_tag="ACZPB4_14380"
     CDS             complement(3579..4118)
                     /locus_tag="ACZPB4_14380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma-70 factor"
                     /protein_id="HIR1099437.1"
                     /translation="MDLFVLKKIKEGDIKAFESIFRLYYTPLCLYATSITGELEVAEE
                     IVQDLFYVFWKERESLPILRSIKNYLYGATRNRSLQYLEHQEVRYRYRNTVLAGENPE
                     SESYTPQDQLEYKELQSLVNRALGKLPERRLRIFRMHRFEGMKYAEIASSLSLSIKTV
                     EAEMTKALQTLRKEIENYT"
     gene            complement(4201..5466)
                     /locus_tag="ACZPB4_14385"
     CDS             complement(4201..5466)
                     /locus_tag="ACZPB4_14385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase-like regulatory
                     domain-containing protein"
                     /protein_id="HIR1099438.1"
                     /translation="MKALCKQTMGFILMILLACGVTSIKAQDSADDEFITVSGVVKDK
                     QTRKKLEYVNISIPGTNVGTITNNDGEFSIKVKNGLHARQVEVSHIGYLNGLIPVNDK
                     DILECTVLLEPNMNTLSEVIIRAGDPRYIVEEAIEKVNKNYIATGSMLTGFYRETAQK
                     GRRYINISEAVIDVYKTPYKDRNVERDRVQIYKGRKLLSEKASDTLAVKLLGGPNLSV
                     YVDVVKNPDLLLDPNILPYYAFRMEESVMLNDRPHYVISFQPQAILPYALYYGKLYID
                     KERLSFSRAEFALSMDDRNKATEAILRKKPFGLRFKPVEVAFLVTYKERDGMSYLSYI
                     RNEVRFKCDWKRKLFSTNYTIVSEMVVTDGKEQNNSIPYRMSFKADQSLSDKVSDFAD
                     ENFWGAYNIIEPTESLENAVYKLKKQHKN"
     gene            complement(5553..6479)
                     /locus_tag="ACZPB4_14390"
     CDS             complement(5553..6479)
                     /locus_tag="ACZPB4_14390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogen peroxide-inducible genes activator"
                     /protein_id="HIR1099439.1"
                     /translation="MNIQQLEYILAVDTYRHFAKAAEHCRVTQPTLSMMIQKLEDELG
                     IKLFDRNLQPVRPTPAGRKVIEQARNVLYQASLIKDIVNEEEQSLKGTFRLAVLPTIA
                     PYLLPRFFQQLSEKHTDLDIRMLEMKTAPTMAALQNGEIDAAIIANQPTESYLQGDIL
                     YYEQFFGYVAHNESIFKKDLIRTADINDERLWLLDEGHCFRDQLMRFCQMEKVKVRQA
                     AYRLGSLETFMRMVESGNGITFIPELATLQLSKEQKELVRPFAIPKPTREIVFVTRKD
                     FIRHTVAGILIESIKKAVPKEMLTLQPGQKVV"
     gene            6771..7520
                     /locus_tag="ACZPB4_14395"
     CDS             6771..7520
                     /locus_tag="ACZPB4_14395"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016758 - hexosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenol monophosphomannose synthase"
                     /protein_id="HIR1099440.1"
                     /translation="MSDSIVIIPTYNEKENIENIIRAVFGLEKVFHILVIDDGSPDGT
                     AAIVKGLQKEFPERLFIVERKGKLGLGTAYIRGFKWAIEHKYDFIFEMDADFSHNPND
                     LPKLYAACTAQGADVAIGSRYCNGVNVVNWPLGRVLMSYFASVYVRIVTGMKIQDTTA
                     GFKCYRREVLETIDLDRVHFKGYAFQVEMKFTAYKCGFKLVEVPIIFINRALGVSKMN
                     SSIFGEALFGVLQLKWWSFFRKYPRKHASHA"
     gene            7560..8906
                     /locus_tag="ACZPB4_14400"
     CDS             7560..8906
                     /locus_tag="ACZPB4_14400"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016812 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds, in cyclic amides
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HIR1099441.1"
                     /translation="MNKILIQNPRIINEGRSFIGSVLVEGDKIAAVFEGEVPGNVRAE
                     ANQVIDATGKWLIPGVIDDQVHFRDPGLTHKGDIGTESRAAVAGGVTTFMDMPNTKPQ
                     TTTIADLEWKFNRAAEVSRANYSFFFGGTNDNMDEIRRLDRSRVPGLKLFLGSSTGNM
                     LVDKKDSLERIFGEAGMLIAIHAEKEEVIRRNIQYYTNLHGEDLDISFHSKIRSEEAC
                     YQCSAEAVELATRLDSRLHILHLSTEKELSLLSNHLPLSEKKITGEVCVHHLWFHDGD
                     YARFGNRIKWNPSIKTIEDRAALREAVNNNTIDIVATDHAPHLPEEKQGSCLKAASGG
                     PLIQHSLITMLELAMEGRFTYEKVVEKMAHMPAELFRIDRRGYIRPGYYADIVLIDPE
                     RTWTVSKENILYKCGWSPFEGYTFHHGVWKTFVNGELAYGDGVVNDAVRGKEVRYL"
     gene            complement(8943..9488)
                     /locus_tag="ACZPB4_14405"
     CDS             complement(8943..9488)
                     /locus_tag="ACZPB4_14405"
                     /EC_number="4.3.99.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016840 - carbon-nitrogen lyase activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="7-carboxy-7-deazaguanine synthase QueE"
                     /protein_id="HIR1099442.1"
                     /translation="MRKINEIFYSLQGEGFHTGTPAVFVRFSGCNLRCSFCDTRHEEG
                     VMMTDEEIVEKVSSFPARMVILTGGEPSLWIDKTLISRLREAGKQICIETNGTRPLPD
                     GIDWVTCSPKENAPVVLERVDEIKVVYTGQDLSAYAEIPARYHFLQPCSCQNTKEVVD
                     YILRHPRWRLSLQTHKLIDIQ"
     gene            complement(9475..9807)
                     /locus_tag="ACZPB4_14410"
     CDS             complement(9475..9807)
                     /locus_tag="ACZPB4_14410"
                     /EC_number="4.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005839017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-pyruvoyl trahydropterin synthase family
                     protein"
                     /protein_id="HIR1099443.1"
                     /translation="MYTVIKRMEISASHSLRLSYPSKCENLHGHNWMITVYCRSKELN
                     ADGMVVDFSHIKRSVKSLLDHQNLNDILPFNPTAENIAFWVYEQIPSCFKVEVKESEG
                     NTAIYEED"
     gene            complement(9968..11092)
                     /locus_tag="ACZPB4_14415"
     CDS             complement(9968..11092)
                     /locus_tag="ACZPB4_14415"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hybrid sensor histidine kinase/response
                     regulator"
                     /protein_id="HIR1099444.1"
                     /translation="MDKLASEYKVLIVDDVPTNVMLVQAILKKEGYTLLTCDSGTKAL
                     RIANEKHPNLILLDIMMPEMDGYEVLQHLKSNPETTDIPVIIMSALSDMQSIVKGYQL
                     GATEYVTKPFQREELVKRVAHRYELYSIKRIKAELENTIESRDTLYSVIAHDLRSPLG
                     SLKMMNNAILMMVDKERVGDEVYEMIQMMNKTSEEIFLLLDNLLKWAKNRLNKQHVYK
                     QQTDINSIIDSTAEMYIPMAAQKGVKIILENLDKELVGLVDIDMLKTIIRNLISNAMK
                     FSFEGGTITLSSRSEGDFVTVSVKDTGKGIKKEDQDKLLKQDSHFTTYGTKNEKGSGL
                     GLMLCKDFVELHGGKLWFESEGEGKGTTFLFSMKALNQEA"
     gene            complement(11205..>11689)
                     /locus_tag="ACZPB4_14420"
     CDS             complement(11205..>11689)
                     /locus_tag="ACZPB4_14420"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009101 - glycoprotein biosynthetic process
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HIR1099445.1"
                     /translation="AMRGYKIAYSKEAYALESASLNMREEEKRKVRISAGGLQSVWRL
                     RGLLNIFRYGILSFQYISHRVLRWTLTPVVLFALLPLNLLLACTGHTLYTVILALQLA
                     FYLLGYLGYKMEKRNIRNKLLFIPYYFLFMNINVIRGYSYLAKHKGTGAWEKAKRGAG
                     "
BASE COUNT         2910 a         2586 c         2844 g         3349 t
ORIGIN      
        1 cgcacggtag gcaaagtcct taaacgaggc gattatgtag tatacgaatc taccgtatat
       61 ccgggatgta cggaagagga ttgcatcccg atcttggagg aggtttcagg gttgagagta
      121 ggagaggact ttaaggttgg atactcaccg gaacgaatca atccgggtga taaggtacat
      181 accttggtaa ataccgtgaa gatcgtttcc ggctgcgatg ccgaagcttt ggaaacgata
      241 tcggaagtct ataagctggt cgttcaagcg gggttgcacc gtgcgcctag tatcaaggta
      301 gccgaagccg ccaagattat cgagaatacc cagcgtgacg tgaatatagc ccttatgaac
      361 gagctttcca ttattttcga tcgaatgggg gtaaatacgt ttgatgtctt gaaagccgcc
      421 gggacgaaat ggaatttcct gcctttctct cccggattgg taggtgggca ttgtataggg
      481 gtagatcctt actatctggt gcataaagcc aaagaattgc aatatcacac gaagatgatc
      541 aactccggtc gctacgtgaa cgattccatg ggacggtata tcggaaagaa ggtcgtgaaa
      601 aagattatct cgcaggggaa aaatatccta ggagcgcatg tgttggtgat gggtatgact
      661 tttaaggaaa acgtatcgga tatacgtaac tcgaaagtag ccgatattat caatgagttt
      721 aaggacttcg gagccgaggt cgatgtgatg gatccgttcg cttccccttt ggaagtattg
      781 caagagtacg gtatccggtt agtagagagg cccgggaaga aatatgacgc ggtagtggta
      841 gctgtcgctc atacgactta tttgaagctg gatgagtcct acttcatgtc gatcacgaac
      901 gaacatgccg tgttggcgga cgtgaaagga gtctatcgag gtagcatcca tcagatgatc
      961 tattggagtc tgtaattgtt aaaaagtaac acaagctgca aagaaatttc gataaactta
     1021 aaaaaatgtg ttgtacaata tcttttttta tttgctcaat tatattaatt agcccatctt
     1081 tgcatgcaga taacctaaac aatctttttg ccttaaagac taatacctat taaaaaccta
     1141 taaagagagc ctttgcgaaa aggctctctt tatgattttt aggggattag tagttcgttt
     1201 cctctatctt tgaggtgatt ctgctaatag cctcattcag tttgtcttcg ggtaatatta
     1261 cgttaaaatc tccccagaaa ccctcgtcgt agttgaagtg agtatccgag aaaaccgtgc
     1321 gggtgggaag ggattcaatg cgtgagaagc ggttcacatt ggttgtatct atcttacagg
     1381 taaccatttc gaaccaagta tgtaaaatat ttgtgttaaa aagttgtctt ctttttttaa
     1441 ttttaaaatg cagatctccc cggatatggt taatgtagta ggtgccattc cattgcttgt
     1501 aagataccgt ataggctact ttctggggcg tgatccgtaa attccggctt tttctctcga
     1561 cgaacatgcc ggccgcttgc tcgatatatt ggggattgac ctcaaagtcc acccttaata
     1621 aggcattatt ttccatgtcg atatatatct gtccccgata aagcggttca ttgatactct
     1681 ttcgttgctc gaaagagatg acgttagcaa gtcgatcatc cactaccgtg atgtcggtat
     1741 gggcgtatgt atagggtgaa tccgggctag gatccagaaa ctccggtaac tgtttcatca
     1801 agtccaagac aaggcaggag tagatacccg acttcatttt tgtgatcaat gtgtcctttt
     1861 cctgctcgtt actgatgcgg cgcatcttta gtagtttcac ttgatcggcc aaggcattgc
     1921 tgtggtaaga tgccttatat accttaaaaa cagcctcggt cagtcctacg agtccttttt
     1981 tacgttcaac gccttctctg taaaatgtgg taaggtaaat cgggtgctgg gaataattgc
     2041 ttcttctctt gtccagcatc tcctgtaata agcgtttcgg attggttaga cgcacgataa
     2101 cttcttggat agagattact ttaggctcta gagataagac ggtatgttta tctattaact
     2161 cccgactatc tatctcttgg ggaagatagc cgatatgaga gaaacgtacc ttggataacc
     2221 ggagtgagtc cggtaatttc aatcggaact ctccattctg gttggtgatg gtgccaatag
     2281 cggcctcacc gattcctacc gatccgaatg cgattggctc atgggtatat tgatcctgta
     2341 aagaaccttc tatcgagaaa taggtttgta tggaatcggg agttacggat acacttttgg
     2401 gagcggagag actctctggc atataaagta ggagatggtt ctctatcgca cggatcgcca
     2461 gatttttatt accggtaata gcgtatatgg cttcttgtat cgtataatct ccacctttta
     2521 ttgatgttgt ttgttcatta tcgataatct tactgtcgta tataaaaaga tagccggaac
     2581 gttccgtgac gagtcccagc aattggtaga tatttccttt tgatttaggc aatcgtatga
     2641 cctgtcccag tacgttacca ttctgggcat tcatagggat gagagctacg agtaacagta
     2701 accatcctac gaccagctgt ctcaaggttc ggaaatcatc catatattat tttgttgcgt
     2761 acattttagt tttaacgctg cgcagatcag ttcagccatc gtcgcgggtg agttattata
     2821 gaaactaacg gtcagccgtc tattctctaa atcagccgtt gtcttcaatg gcatcttcgg
     2881 atattccaga ttaattacat gcaagatatc tcccagacgc tcatccttaa attggatacg
     2941 gcgggtgtaa tcggaaaatt gttcgttatc ttgagtcgga actacttgta aacggttgga
     3001 gaataaggat acggtttggc cggcctttac cagcgtttgt tctccgttct tcttgagtgt
     3061 cactttcact aatccccggc gaacggccaa ttcaaaggcg cttttatccg agcttttgat
     3121 attgaatgag gttcccaata cctcgatccg ggcctgctct gtctcgatta ggaaaggacg
     3181 ttccttattc ccgcttacat caaaaagagc gtttcctagt agagacacct ctcttttttc
     3241 tctttggaaa tgttccggat agcttaactg gctgttatcg gccagataaa cgatagaccc
     3301 gtcttccaaa gtcgtgacca aggtggtgga agcctcgtta ttatgcaggg tgagcagagt
     3361 ggtctccggt gtccgttctt gtccaaggaa aatagctgta gctaccgata cacaaagtat
     3421 gatgatagcg gcggcccatt tcataagtcc gatccggtat gggatttgtg taccggaaat
     3481 tggcttatcc agcagcccgt cttgctccaa gcgagtatat aattgttccc atgcttggtc
     3541 tgtcttcaat ttattttttt ctatttgatt cataactgtt aggtataatt ctcgatttct
     3601 tttcttagtg tttgtagtgc cttggtcatt tccgcttcta ctgtctttat ggacaatgag
     3661 aggctggagg ctatctccgc gtatttcatt ccttcgaaac ggtgcatccg aaagatccgg
     3721 aggcggcgtt cgggcaattt acctaatgcc cggttgacca aggattgcaa ttctttgtac
     3781 tcaagttgat cttgcggggt atacgattcg gattccggat tctctccggc taaaaccgta
     3841 ttccggtatc ggtatcgtac ttcctgatgc tccagatatt gtaaggaccg gttccgggta
     3901 gctccataaa ggtagttctt gatggaacgt aagatcggaa gagattctct ttctttccag
     3961 aacacgtaaa acaagtcctg gacgatctcc tccgcgactt ccagctctcc tgttatactg
     4021 gttgcgtaca ggcaaagagg ggtataataa agcctgaaaa tactttcgaa tgctttaata
     4081 tccccttcct tgatcttttt gagtacgaac aaatccataa taatttggtt tcaacagata
     4141 attgataatg gacaaagata atgatttgtc catatcattg tcgatagtat atttacacgg
     4201 tcaattttta tgttgcttct ttaatttata taccgcattc tccaaagact cggtaggctc
     4261 gataatgttg taagctcccc agaagttctc gtcggcgaag tccgatacct tgtcggatag
     4321 agactgatcc gctttaaaag acatccggta ggggatggag ttattttgtt ctttaccatc
     4381 ggtaacgacc atctcggata cgatcgtgta gttggtagag aaaagttttc gtttccagtc
     4441 gcatttaaag cgaacctcat tgcggatata actcagatag ctcatgccgt cacgttcttt
     4501 gtaagttacg aggaaagcta cctccacggg tttaaatcgc aagccaaaag gctttttgcg
     4561 gaggatggcc tcggtagcct tattccggtc atccatgctg agggcgaatt ccgcacggct
     4621 gaaggaaagc cgttccttat cgatatacaa tttaccgtaa tataaggcgt aaggcaagat
     4681 cgcttgaggt tggaaactga ttacgtaatg cggtcggtcg tttaacatca cgctttcttc
     4741 catacggaag gcgtaataag gtaagatatt cgggtcgagc aataaatccg gattcttcac
     4801 cacatccacg taaacggata ggttagggcc tcccaataat ttcacggcta atgtgtcgct
     4861 agccttctcg ctcaataatt tacgtccttt atagatctgt acccgatccc gttccacgtt
     4921 cctgtcctta tagggagttt tgtaaacatc gataaccgct tccgagatat tgatgtaacg
     4981 acggcctttt tgtgcggtct cccggtagaa cccggtaagc atgctacctg tggcgatgta
     5041 attcttattt actttctcaa tcgcctcctc tacgatatat cgaggatctc cggcccggat
     5101 aatgacttcg ctaagcgtat tcatgttcgg ttcgagtaat accgtacatt ctaatatgtc
     5161 cttatcgttc acggggatca agccattcaa atatccgata tgcgatactt ctacttgtct
     5221 ggcatggagg ccgtttttca ctttgataga gaactcaccg tcattattgg tgatcgttcc
     5281 cacgttggtt cccggaatag agatatttac gtattccagt ttttttcgtg tttgcttgtc
     5341 ttttactaca ccgctgacag tgataaactc atcgtctgcg ctatcctgtg cctttataga
     5401 ggttacaccg caagccaaca gtatcatcag gataaatccc atagtttgtt tacagagcgc
     5461 tttcatattt gtattgtttt aatggtaaat aatcactttg tacttatatg atcgcccagg
     5521 aaagaaatac cctatgggat ttatcaaaaa aatcacacaa ccttttgtcc gggctgcaaa
     5581 gtcaacattt ctttaggtac cgctttcttg atgctctcta ttaaaatacc cgctacggta
     5641 tgccggataa aatctttacg ggtgacaaag acgatctccc gtgtcggctt gggaatggcg
     5701 aacggacgta ccaattcttt ctgctcttta cttaactgca gggtagccaa ttccgggatg
     5761 aacgtaatac cgttaccgct ttccaccata cgcataaatg tctctaggct acctaaacgg
     5821 taagcggctt ggcgaacctt taccttctcc atctggcaga aacgcatcag ctggtcacgg
     5881 aagcaatgtc cctcgtccaa cagccacaac cgctcgtcgt tgatatcggc ggtacggatc
     5941 aaatcctttt tgaagataga ttcattatga gccacgtatc cgaagaattg ctcataatat
     6001 aatatgtctc cttgtaaata ggattctgtg ggttggttcg ctatgatagc ggcgtcgatt
     6061 tccccgtttt gcagggcggc catagtggga gcggttttca tttccagcat acggatgtca
     6121 agatccgtat gcttttccga taattgctgg aaaaagcgag gtagcaaata aggggcgata
     6181 gtcggtagca ccgctaagcg gaacgtacct ttcaatgact gttcctcctc gttcacgata
     6241 tctttgataa gagaagcttg atagaggaca tttctcgctt gctcaataac cttacgtccg
     6301 gcaggtgtgg ggcgaacggg ctgcaggttt cgatcgaaca atttaatacc tagttcgtct
     6361 tccagctttt ggatcatcat actcaatgtc ggttgtgtca ccctacaatg ctctgctgcc
     6421 tttgcgaaat gacgataagt atccaccgct aggatatatt cgagttgctg tatattcata
     6481 gtacttaatt ttacaagcgt tagaaattaa tgaagacaaa cttacggaaa aacgctggaa
     6541 taatcgaata aaagtggaag aataaagcaa cttaatttga gtattaggca tttaggggga
     6601 aatcggggaa gttgggtgaa aagccaaaat acatttgctt atcatggaac agacgaatgg
     6661 gctaacagga tgatagattt acacagaaaa aatatgtaac tttggagagt aatttacaaa
     6721 tggtttacag tcgtatatat aatgagctaa aaattaattg attaaagtat atgtcagaca
     6781 gtatcgtcat tattcctaca tacaacgaga aggagaatat tgagaatatc attcgtgccg
     6841 tgttcgggct ggagaaagtg tttcatatct tggtgatcga tgatggctct ccggatggga
     6901 cggcggctat cgtgaagggc ttgcagaagg agttcccgga gcgtcttttt atcgtggagc
     6961 gtaaggggaa gctgggattg ggtaccgctt atatccgggg ttttaaatgg gctatcgagc
     7021 ataaatatga ttttattttc gagatggacg ccgatttcag tcataatccc aatgacctgc
     7081 cgaagctata cgccgcttgt accgcacagg gtgccgacgt agccatcggg tcgaggtatt
     7141 gcaacggggt gaatgtggtg aactggccgt tgggccgtgt gttgatgtct tatttcgcct
     7201 cggtgtatgt ccgtatcgtc acgggtatga agatacagga tacgacggcg ggctttaaat
     7261 gttaccgccg tgaggtgctg gagacgatcg atctggaccg tgtccatttc aagggatacg
     7321 cctttcaggt ggagatgaag tttacggctt ataagtgcgg cttcaagctc gtggaggtgc
     7381 cgatcatctt tatcaaccgt gccttgggtg tctccaagat gaactcttcg atattcgggg
     7441 aggctttatt cggcgtcctt caattgaaat ggtggagttt cttcaggaag tatccgagga
     7501 aacatgcgag ccatgcctaa tgaaaacaga gtttgacaat ttataatagg ataagaaaga
     7561 tgaataaaat attaatccaa aatccgagaa tcatcaacga gggccgttct tttatcggct
     7621 cggtgttggt ggagggggat aagatcgcgg cggtgttcga gggggaggtt cccgggaacg
     7681 tgcgtgccga ggcgaaccaa gtgatcgacg ctacggggaa atggttgata ccgggcgtca
     7741 tcgatgatca ggtgcatttc cgggaccccg ggcttaccca taagggggat atcgggaccg
     7801 agagccgtgc ggccgtggcc ggtggcgtga cgaccttcat ggacatgccg aacacgaagc
     7861 cacagaccac gacgatcgcc gatctggaat ggaaattcaa ccgtgccgcc gaggtctccc
     7921 gtgcgaatta ctccttcttc ttcggtggga caaacgataa tatggacgag atccgcaggc
     7981 tggatcgtag ccgtgtgccg ggactgaaac tcttcctcgg ctcgtctacg ggaaatatgc
     8041 tggtggacaa gaaagactcg ttggagcgta tcttcggcga ggccggtatg ctgatcgcca
     8101 tccatgcgga gaaagaggag gtgatccggc gtaatatcca gtattacacg aacctgcatg
     8161 gcgaggatct ggatatctct ttccatagca agatccgtag cgaggaggcc tgctaccaat
     8221 gctcggccga ggcggttgaa ctggctaccc gcttggattc ccgtttgcat atcctgcatc
     8281 tctccacgga gaaggaatta tcgttgctca gtaaccatct tcccttgagc gagaaaaaga
     8341 taaccggcga ggtctgcgtg caccatctat ggtttcatga cggcgattac gctaggttcg
     8401 gtaatcgtat caagtggaat ccttctatca agacgatcga ggatcgcgcg gcgctgcgtg
     8461 aggcggtcaa taacaatacg atcgatatcg tagctaccga ccatgccccg catctaccgg
     8521 aggagaagca aggctcttgc ctgaaggcgg cttccggagg accgcttatc cagcactcct
     8581 tgatcacgat gttggagctg gcgatggaag gccgtttcac gtacgagaag gtggtcgaga
     8641 agatggcgca tatgccggcg gagctgtttc gtatcgatag gaggggatac atccgtcccg
     8701 gatactacgc cgatatcgta ttgatcgatc cggagaggac ttggacggta tcgaaggaga
     8761 atatcttgta caaatgcggc tggtctcctt tcgagggtta tacgttccac catggcgtat
     8821 ggaagacttt cgtgaatggc gagttggcct atggcgatgg agtggtgaat gacgccgtga
     8881 gaggtaaaga agtccgttat ctatagtagt agagacgggg gagatacccc gtctcaccct
     8941 atctattgga tatcgatcag tttatgggtt tgcaggctta gcctccaccg gggatgccgg
     9001 aggatgtaat ccactacctc tttcgtattt tggcaggagc agggttgcag gaaatggtac
     9061 cgtgcgggga tttcggcgta tgcggacagg tcttgcccgg tataaaccac ctttatctcg
     9121 tcgactcttt ccaataccac cggggcgttc tccttgggcg agcaagtcac ccagtcgatg
     9181 ccgtcgggca aggggcgtgt gccgttggtc tcgatacaga tctgtttccc cgcctcacgt
     9241 aagcgggata taagcgtctt gtcgatccac aggctaggtt ctcctcccgt caggattacc
     9301 atccgtgcgg gaaaggaaga taccttctcc acgatctcct cgtccgtcat cattacgccc
     9361 tcctcgtggc gggtgtcgca gaagctacat ctcaggttgc aaccggagaa gcggacgaat
     9421 acggcgggag tccccgtatg gaacccttcg ccttgcaagc tgtagaatat ctcgttaatc
     9481 ttcctcatag atcgccgtgt taccctcaga ctcttttacc tctaccttga aacaagacgg
     9541 gatctgctcg tatacccaaa aggctatgtt ctccgccgtc gggttgaaag gcaggatatc
     9601 gttcaagttc tggtggtcca acagggattt caccgatctc ttgatatggc tgaaatcgac
     9661 taccatgcca tcggcgttta attccttgga gcggcaataa accgtgatca tccaattgtg
     9721 accatgtaga ttctcacatt tgctggggta ggacaatctc aagctatggg aagcggagat
     9781 ctccatacgt ttaattacgg tatacatacg ataataatgt ttatacgata aataataatg
     9841 tacctaatgt cacctcggca cacaaaaaaa tcccggatat taatccggga tgcaaatata
     9901 cgaaatattt agtttgtttg tacgacactt gtctacgatc ggtagagaca ggcggtacgt
     9961 cgatcggcta tgcctcttgg ttcagcgcct tcatcgagaa caggaaggtc gttcctttgc
    10021 cctcgccctc ggactcgaac caaagctttc ctccatgaag ctccacgaag tccttgcaaa
    10081 gcatcaatcc cagaccggag cctttctcgt tcttcgtccc gtaggtcgtg aaatgcgagt
    10141 cttgtttcaa gagcttgtct tgatcctctt tcttgatgcc cttgccggta tctttcacgc
    10201 taacggttac gaaatccccc tcggagcgtg aggataaggt gatcgtgccc ccctcgaaac
    10261 taaacttcat ggcgttagag atcaggttac ggataatcgt cttgagcata tcgatatcga
    10321 ccaagcctac cagctcttta tccagatttt ctaggataat cttcacgcct ttttgcgccg
    10381 ccatcgggat atacatctcg gcggtactgt cgatgatact gtttatgtcg gtctgttgct
    10441 tatatacgtg ctgcttgttc aagcggttct tggcccattt cagcaggttg tccagcaaga
    10501 ggaagatctc ctcggaggtc ttgttcatca tctggatcat ctcgtacacc tcgtcgccta
    10561 cccgctcctt gtccaccatc atcaagatgg cgttattcat cattttcaac gagcctagcg
    10621 gggaacgcag gtcatgggcg ataacggagt atagcgtatc cctagactcg atcgtgttct
    10681 ccagctcggc cttgatgcgc ttgatgctgt aaagctcgta gcggtgggcc accctcttca
    10741 ccagctcctc acgttggaaa ggctttgtga cgtattcggt ggcgcccaat tggtaacctt
    10801 tcacgatgct ttgcatatcg cttagggcgg acatgataat cacgggtata tccgtagtct
    10861 cgggattgct tttcagatgc tggaggacct catatccgtc catctcaggc atcatgatat
    10921 cgagtaatat cagatttggg tgtttctcgt tagctatgcg tagcgctttt gtcccgctgt
    10981 cgcaagtcaa aagcgtatat ccctctttct tcagtatggc ttgtactagc atgacgtttg
    11041 tagggacatc atctacgata agaactttat actctgaggc caatttatcc attgtatcta
    11101 aattgtgttc tagttttctt gatattcaaa tagtatcaat agcgcaaaag tattaattaa
    11161 agtcgacata taacgactat ttatccatct atttttttat ttttttatcc cgcgcctcgt
    11221 ttggcttttt cccaagcgcc tgtgccttta tgcttagcga gatagctata ccctcgtatg
    11281 acattgatat tcatgaataa aaagtaataa ggaatgaata atagcttgtt ccggatgttc
    11341 cgtttttcca ttttataccc caagtatccc agcaggtaaa acgctaattg cagggcaagg
    11401 atgaccgtgt aaagggtatg cccggtacag gcaaggagca ggttgagggg caggagggcg
    11461 aagagcacga ccggcgtcag cgtccagcgc agtacccggt ggctgatgta ttggaagctc
    11521 agtatcccgt accggaagat attcaataat ccccgtagcc gccataccga ttgcaatcct
    11581 ccggccgata tgcgtacttt acgtttctcc tcctcccgca tgttcaggga ggcgctctcg
    11641 agggcgtacg cctctttgct gtaggcgatc ttgtagcctc tcatcgcta
//
LOCUS       DBMDTB010000113        11372 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_1703_length_11372_cov_11.705616, whole genome shotgun
            sequence.
ACCESSION   DBMDTB010000113 DBMDTB010000000
VERSION     DBMDTB010000113.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 11372)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 11372)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11372
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1703_length_11372_cov_11.705616"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..366
                     /locus_tag="ACZPB4_14425"
     CDS             <1..366
                     /locus_tag="ACZPB4_14425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin type III domain-containing protein"
                     /protein_id="HIR1099446.1"
                     /translation="PARVRYVRYKNIEVPTPHLAISDLRVFGIGEGKKPATVKNFKVV
                     RQADRRDAMITWDAVKNSQGYNIRWGIAPDKLYNSWLLYGKNELLLKSLSTDQPYYFT
                     IEAFNENGVSEATKIQEAQ"
     gene            638..1435
                     /locus_tag="ACZPB4_14430"
     CDS             638..1435
                     /locus_tag="ACZPB4_14430"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylesterase family protein"
                     /protein_id="HIR1099447.1"
                     /translation="MIMKTLRSIFFLSLCLLLSIAGYAGDKASFLKKQFTARDGYQLN
                     YRVLYPRDYNPAQKYPIILFLHGAGERGSDNEAQLIHGGDMFASFENQTKYPAIIIAP
                     QCPAEKTWSEYKGLNAGKEGKRFYPLNAPATQSMAAVKELLDSYIAEGKVDTKRIYVT
                     GLSMGGMGTFDIVMRYPNLFAAATPICGGANLQRLANFKGKTAFSIYHGGSDSVVDVQ
                     FSRDANEALKKAGADVRYKEFPGVDHNSWDNAFAEPDYLAWMFQHSL"
     gene            1610..2197
                     /locus_tag="ACZPB4_14435"
     CDS             1610..2197
                     /locus_tag="ACZPB4_14435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HIR1099448.1"
                     /translation="MKNEFILKTLLSRVAKGDYASFRELFDIQYATVNRFVGYFLPNK
                     EDREEVVSEVFCILWKRREELIDIEDLNAWLFIISRNESFHYLKQKEHQRQNISIDEL
                     PIDLYIDTNEVDSDLLDAEMTEVYNKALSELPERCKLIFLLAREERMKHKEIAQALSI
                     TEGTVEQQMNIAIRKMLDAVSRYYNVVKRRIHLLF"
     gene            2303..3241
                     /locus_tag="ACZPB4_14440"
     CDS             2303..3241
                     /locus_tag="ACZPB4_14440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecR family protein"
                     /protein_id="HIR1099449.1"
                     /translation="MIVDNQKNQEKEIKLILQLLNAIKAKHTLSVQEAEEGKEAVFKR
                     VEEKLGRRYNLTATRRTRLFRYWPVAASIAILILSSVIVSIGIINSRQVLTAQAPIVV
                     EVPEGAITHLTLSDGTQVTLNGGSSLTYPAEFSDNREVCLQGEGFFDVRKKMESPFIV
                     HTKQFSAKVLGTRFSFKAYDTDRQAVLTLERGSVQVLTDHGKENMILSPNQQVIKDSH
                     TGKLYCHEVDAEDYTCWKDGILVFKDQTLAEISTILERRFNVRIEIDSESIKYDKYVA
                     SFRKHVSLDDILKKLSYQRSWTYIQKDGKIKLVKNV"
     gene            3345..6659
                     /locus_tag="ACZPB4_14445"
     CDS             3345..6659
                     /locus_tag="ACZPB4_14445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SusC/RagA family TonB-linked outer membrane
                     protein"
                     /protein_id="HIR1099450.1"
                     /translation="MKKDTGIRVKYGVPYFIVRVMAIGMLFLILNTSNILAATESPVV
                     LDLSLNQTTLEQVFRELEKQSGYSIIYKSSEVNLKEVLSVDVSKEPLENVLNKVLRKQ
                     GLTYEIKDEHIIIYKAKANKEIHAVIKQQNKKISGVVKDAQGEPMIGVSVLEEGTQNG
                     TVTDFNGNYVLEVQNGKAALVFSYIGYVSKKVSIGNLSVVNVALDEDVQRLDDVVVVG
                     YAIGNKRSVSGAVEKVKKEDMNSGVVTEPLDAVKGKVAGVVISNVGGDPTSDMNIRIR
                     GTTSLSGGNDPLVIIDGVFGDLSMLNAISPSDIESLTILKDASETAQYGSRGASGVIV
                     VTTAKGRAGFAQIEYNGLFGVNKVYKNLGMLTADEWRAGAVAMGLSTNDMGASTNWFE
                     EVERSASLTQTHNLSFTSGNDNSNLRASLGVIRRPGLLKNSSSNSYTAKVDASQYAFQ
                     KRVKFDLGMFGSRREGDHQFDMYRTIYSAAAYNPTYPNYKNPETGIWDEDKTAIEVYN
                     PLGMLEITNKKIASHVNVNGRVNVEIIKGLNLTGFGSYTYYSLNDRRYIPNDIQQGSM
                     NGNGQAYLKYAERNDLMGNLQLNYAREFGRHSINALALLEAQTQSLFESSTKTSGYET
                     NYFTYNNLKAGANISWGDATSNATRFALLSYMARFNYMYDSRYVVTANVRRDGSSKLG
                     YGNKWGFFPSASVAWIASNEAFMKSLTFIDNLKVRAGYGVTGNQDAIDPYQSLSLMAP
                     NGTTLVDGSATTTFYIDSNPNPDLRWEKKYTFDVGVDLAMFQSRLRLTMDYYASTTKD
                     MLYTYTVPVPPFVYTSMLANLGEMTNNGFEVAISGDIIKKKDFSLTVGTNLSFQKNKL
                     KSLSGTYMGSEFTTSKYIQVSAVNAPSLTQYAGVTYLTEGQPLGVFYIPHCNGLVEKE
                     DGKFVYDIADLDGDGKVDLSDSGDRYIAGQALPKVYMGGFVNMRYKDFDLAVQLNGAF
                     GHKIYNGTSLTFNNLSLYPTYNILDGALDKRIYDIKISDYYLENGNYVNIEYITLGYN
                     IPVKKLKIEKYLKSLRLAFSVNNVATITGYSGMTPLINSANVASKSSVSGTLGVDDKL
                     IYPLSRTYSLSLGVKF"
     gene            6686..8374
                     /locus_tag="ACZPB4_14450"
     CDS             6686..8374
                     /locus_tag="ACZPB4_14450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RagB/SusD family nutrient uptake outer membrane
                     protein"
                     /protein_id="HIR1099451.1"
                     /translation="MKKVLVSSMLILGGLFSACSGFLDEDPKSKIPEEEAYKSEKLVY
                     VNTIATIYTSFGNRLYGSTDNVHTLQEFSSDAWILPGRQGDWVDGGKWQSLFLHNYGP
                     GNATIKSTWNALYTIIGNCNTSIDNLETFIQAGGESYLQDYQYEARAVRAILYYHLVD
                     LFGRVPLVTSSKTVMADVNQSSRSEVYQFIVDELTDCIPHLPSGKCQNMGKYYGRVTK
                     AVGYMAMAKVAINSPILSKDDWNDGSLVGGIAKVAPYVNQAGKNIKIALDGTTRDAWE
                     TVLYCQKQIEKEGYSLQPNFSQNFSKTNDSSVENIWTQPSDGTTYKVSDYNPTRTLHA
                     AHASAYGLQGWNGACATVEQMKVFKYGTDEQDPRMDMTFFYGPVFVDGKPIDAGLGDG
                     AQLCYNPMDVVVDFKEDVPNQILKFAGARMSKYEVDNTTSSYLNHNNDKVFWRYADAL
                     LLAAEAKVRMGQSGDAEVNEIRDRVQAGQKSNVTLQDILDERMLEFSYEGMRRQDQIR
                     FGTYTEPTTDRYAGVHHNVATGDYVVDNTGFTTVFPIPTSVLELNTKLTQNPGY"
     gene            8394..11294
                     /locus_tag="ACZPB4_14455"
     CDS             8394..11294
                     /locus_tag="ACZPB4_14455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIM-barrel domain-containing protein"
                     /protein_id="HIR1099452.1"
                     /translation="MRCKYLLLYGLLAVLPFSAQAGYKKIANGILVSLPEGELNQSKT
                     VRLLVVNDEVIQVTASPEAKIQDKQSLVRVAPVKAPVKWNVESTSDSVFLNTGKLRAA
                     VSLVTGEVTFYDMSGKLILRESNGGRHFTPIEVEGRKGYTTRQQFNSPEDEAFYGLGQ
                     HQSDEFNYKSKNEELYQYNTKISVPFVVSSKNYGVLFDNYSYSRYGDPRPYSNLDIFK
                     LYDKNGKEGGLTATYYKNNGLEVFAERQESRIDYETLFTHQPLPKTFDFKGETFDKFP
                     EGFRFRNSLVVWEGEIEPKESGVYHFKLFYGAYTKVFLDNKLVVEERWRPSWNPNSVK
                     FTADLQAGKKVPVRIEWREGAGSYIGLKVLSPRPEEEVGRLSMWSEMGNDIDYYFIHG
                     DSMDEVISGYRYVTGKSPIMPAWAMGFWQSRERYKTQDEILTALRELRKRKMGVDNIV
                     MDWQYWKTDSWGSHEFDPARFSDPKGMVDAIHDLNARFMISVWPKFYPTTKNYKELAA
                     NGWVYLQAVKDSILDFVPPGFVATFYDAYAPGARKLFWKQMNDNLYRLGVDAWWMDAS
                     EPNIKDCTPMSYQKALTGPTALGPSAQYYNTYALVNAQAIYEGQLKENPDDRVFLLTR
                     SGFAGLQRYSTASWSGDIGTRWEELKAQISAGLNFSISGIPYWTMDIGGFCVENRYRT
                     GQLIYDKTGVENDDLKEWRELNARWYQFGTFTPLYRAHGQFPLREIYNIAPEDHPAYQ
                     TILYYNQLRYRLMPYIYSLAGKTYFDDYTIMRPLVMDYASDLAVRDNSTQYMFGPSMM
                     IAPVYTYKATSREVYFPKGTDWYDLYTGKRYKGGQKQEVEAPFERMPIFAPSGGILLY
                     GPEITYVNEKKPEVIDVYIYAGKDGSFYLYEDEGTNNNYQKGTYSKIDFNYSDATNTL
                     TIGSREGSYPGMLSERTFNIIYVSPNAPAGWDNKGKPAKVIEYKGEQISVKL"
BASE COUNT         3203 a         2030 c         2838 g         3301 t
ORIGIN      
        1 ccggctcgtg tccgttatgt ccgttataag aatatagagg tcccgacgcc tcatctggcg
       61 atctcggact tgcgtgtgtt cggtatcggt gagggcaaga aacctgcgac ggtgaagaac
      121 ttcaaggtcg ttcgccaagc ggatcgccgt gacgctatga tcacttggga cgctgtcaaa
      181 aacagccaag gctacaacat ccgttggggc atcgctcccg ataaactata caactcatgg
      241 ctcctatacg gaaagaatga attactttta aagagtctgt ccaccgacca gccttattat
      301 ttcaccatcg aggcattcaa cgagaacggt gtatcagaag cgacaaaaat acaggaagcc
      361 caataatctt tcggtatcat tttcaaatgt attttgtaga gataggaaaa tctgtctcta
      421 caaaatacat acaatattcg attatttact tactaacggg tatttatctg gatttgctat
      481 gatagacaag ctcaaatcta catctaaagc atcccaacga atccgctcac gtcctaatag
      541 ttggtttaat cttgatatta tacaacgcct taacagacta tttaattata tttgcggaag
      601 ttatcgatct aagtagatag tatttacatt tgaatatatg attatgaaaa cacttagaag
      661 tatctttttt ttgtctcttt gccttcttct ctccattgct ggatatgctg gtgataaggc
      721 tagttttttg aaaaagcagt ttacggctcg tgatggttat caattgaatt atcgggttct
      781 gtatccccga gattataatc cggcgcagaa atacccgata atcctgttcc tgcacggagc
      841 gggcgaacga gggtcggata atgaggccca attaatacat ggtggcgata tgttcgcttc
      901 tttcgagaat caaaccaaat atccggctat cattatagcg cctcaatgcc cggccgagaa
      961 gacttggtct gaatataagg gattgaacgc cggaaaagaa ggaaagcgtt tctatccgtt
     1021 gaatgctccg gccacacaat cgatggccgc cgtcaaggaa ttattggata gttatatagc
     1081 ggaaggtaag gtcgatacga aacgcattta cgtaaccggc ctatcaatgg gaggtatggg
     1141 cacgttcgat atcgtgatgc gttacccgaa cctgtttgcc gctgccaccc cgatctgtgg
     1201 tggagcaaat ttgcaacgtt tggcaaactt taagggcaag acggctttca gtatttatca
     1261 tggcggctcc gatagcgtag tcgatgtaca attctcccgt gacgctaatg aagcattgaa
     1321 gaaagcagga gctgatgtcc gttataagga atttcccggt gtagaccata acagttggga
     1381 taacgctttc gccgaaccgg attatctggc ttggatgttc cagcatagct tatagttagt
     1441 aagtcttgta tcttttatag gccttatcat atataagtgc ttccctctta ttaagaagaa
     1501 gctaaatatt tgataaggct ttttgtttat aagtttttta ttacttttgt cacgaaagga
     1561 gagagatgag tccatctgtt atgaaagaca atggatttga ctaatcgtaa tgaaaaacga
     1621 attcatatta aaaactctac tgtctcgtgt tgcgaaagga gattatgcct cttttcgtga
     1681 gttgtttgac atacaatatg ccacggtcaa tcgttttgtg ggatattttc tgccaaataa
     1741 ggaagatcgt gaggaagtcg tatccgaggt attctgtatc ctatggaaaa gaagggaaga
     1801 attgattgat atagaagacc tgaacgcttg gttatttatc atcagtagaa acgaatcttt
     1861 ccattacttg aaacagaaag agcatcaacg ccaaaacata tccattgatg agctaccgat
     1921 agatttgtat atagatacga atgaggtaga tagtgatctg cttgacgccg agatgacaga
     1981 ggtatataat aaagcccttt ccgaactccc cgaacgctgc aaattaatct tcttattggc
     2041 tcgtgaagag cgaatgaagc ataaagagat cgctcaagcc ttgtcaataa cggaaggaac
     2101 cgtggagcaa caaatgaata tcgcaatccg gaaaatgttg gatgcggtga gccgatatta
     2161 caatgtcgtt aaaaggagaa ttcatctgtt gttttaatga atgttaaact cgtgataccc
     2221 tttataggta aaaaagactt ccatactctt tatttataga atcattaatc aaatgtaggt
     2281 ggctcctaca agtaaaaagt gtatgattgt ggataatcaa aagaatcaag aaaaagagat
     2341 aaagctgatt ttacagcttt taaatgcgat aaaagcgaaa cacactttat ccgttcaaga
     2401 agcggaggag ggaaaagagg ctgttttcaa acgggtggaa gagaagttgg gacgtcgtta
     2461 taatctgacg gcaactagaa gaacccgtct attccgttat tggccggtgg ccgcttctat
     2521 cgcaatcttg attctttctt ctgtaatcgt ttctatcgga atcatcaata gtcggcaggt
     2581 cttaacggct caagcgccta ttgtcgtgga agttccggag ggtgctatca cgcatctcac
     2641 cctttctgat ggtactcaag ttacgttgaa tggaggatct agcttgacat atccggccga
     2701 attttccgat aaccgtgaag tgtgcttaca gggtgaagga ttctttgatg tcaggaagaa
     2761 gatggagagc ccgttcatcg tacatacgaa gcaattctcg gcgaaagtat tgggtacccg
     2821 ttttagtttc aaggcttatg atactgatcg ccaagccgtg ttgaccttgg aaagaggttc
     2881 cgtgcaagta ttgacggatc atggcaagga gaatatgata ttatctccta atcagcaggt
     2941 aattaaagat agccatacag gtaaactcta ttgccatgag gtggatgcgg aagattatac
     3001 gtgctggaag gacggtattc tggtgtttaa ggatcagacg ttggcagaaa tctctaccat
     3061 attggaaagg cggttcaacg tgaggatcga gatagactcc gagtcgataa agtatgataa
     3121 atatgtcgca agtttccgga aacacgtgag tttggatgat attctcaaaa agttatctta
     3181 ccaacgctca tggacatata ttcagaagga tggaaaaatc aagctagtca agaacgttta
     3241 atacttaaat taatttgcct atgaagtgaa atctggaaaa gagtgtagga gccaagctat
     3301 ttgaaatgac ctctagttat tgttaatatt taaatttatc tatcatgaag aaagacacag
     3361 gaattcgtgt aaagtatggt gttccatact ttatagttcg tgttatggca atcggcatgt
     3421 tatttttaat actaaatacg agtaatatat tagctgccac agagtctccg gttgttcttg
     3481 atttatctct gaatcagact actttagaac aagtgttccg tgagttggaa aaacaatctg
     3541 gttattctat tatctataaa agtagtgaag tcaatttgaa agaggttttg tctgttgatg
     3601 tcagcaaaga gccactcgag aatgtcttga ataaggttct gagaaaacag ggattgacgt
     3661 atgagataaa agatgagcat attataatct acaaagcgaa ggcgaacaaa gagatccatg
     3721 cggtaataaa gcaacaaaat aagaaaatta gcggggttgt aaaagatgcc caaggagaac
     3781 cgatgatcgg tgtcagcgtg ctggaggaag gtacccaaaa cgggacggta accgacttta
     3841 acgggaatta tgtgctggaa gtacaaaatg gaaaagcggc attagtcttc tcttatattg
     3901 gctatgtaag taagaaggtg agtataggga atctttcggt ggttaatgtt gcattggatg
     3961 aagacgttca aaggctggat gatgttgttg ttgtgggtta cgccatagga aacaagcgtt
     4021 ccgtatctgg tgctgtggag aaagtaaaga aagaggatat gaactcgggt gtcgttacgg
     4081 agcctttgga tgcggtaaag ggtaaggtcg ctggtgttgt tatcagtaat gtaggtggag
     4141 accctacgag tgatatgaat atccgtatcc ggggtactac ctctctatcc ggaggcaatg
     4201 atccgttggt tatcatcgat ggggtatttg gagatttaag tatgttgaac gccatctctc
     4261 cttccgatat agagtctttg actatcttga aagatgcttc ggagacggct cagtatggtt
     4321 cacggggtgc gtccggggta attgtcgtta cgactgccaa gggtagagcc ggtttcgctc
     4381 aaattgaata taatggttta ttcggtgtta ataaggttta taagaacttg ggaatgttaa
     4441 cggccgatga atggcgtgcc ggtgcggtgg ctatgggatt gagtacgaat gatatgggag
     4501 cgagtacgaa ttggtttgag gaggtggaac gttctgccag tcttacccag acccataatc
     4561 tctcatttac gagcggtaat gataattcca atctaagggc ctctctcggt gtgatccgcc
     4621 gtccgggttt gttgaagaat tcttcttcca atagttatac ggccaaagtg gacgcaagcc
     4681 agtatgcttt ccagaaacgg gtgaagtttg atttaggcat gtttggatca cgtagggaag
     4741 gcgatcatca atttgatatg taccgtacga tttattcggc ggcagcttac aatcctacgt
     4801 atccgaacta taagaatccg gaaacgggta tctgggatga ggataagact gcgatcgagg
     4861 tatataaccc cttaggtatg ttggagatca caaataagaa aatagcctct catgtgaacg
     4921 tgaacggacg tgtaaacgtg gagatcatca agggattgaa cttgacggga ttcggttcgt
     4981 atacttacta tagcttgaat gaccggcgtt atatcccgaa tgatatccaa cagggttcga
     5041 tgaacgggaa tggacaggcc tatttgaaat atgcggaacg aaatgacttg atgggaaatc
     5101 tccaattgaa ttacgcaagg gaattcggac ggcatagcat taacgctttg gctttattgg
     5161 aggcgcagac acagtctttg ttcgagtctt ccacgaaaac cagcggttac gagacgaatt
     5221 attttaccta taataacttg aaagccggtg ctaacataag ttggggtgac gctacctcta
     5281 atgctacccg tttcgcttta ttatcttata tggcacgctt taattatatg tatgatagcc
     5341 gttacgtagt tacggcgaat gtccgtcgcg acggttcttc taaattaggt tatggtaata
     5401 aatggggatt cttcccgtcg gcttctgtcg cttggatcgc ctcgaacgag gcttttatga
     5461 agtccttgac ttttatcgat aacttgaaag tgagagccgg atatggcgtg accggtaatc
     5521 aagatgcgat cgatccgtat caatccctct ccttgatggc tccgaatgga acgaccttgg
     5581 tggatggatc ggctacgact actttctata tcgattcaaa tccaaatccg gatttgcgtt
     5641 gggaaaagaa gtatacgttt gatgtgggcg tggatttagc gatgttccaa tcccgtcttc
     5701 gcttgacaat ggattattat gcgtctacta cgaaagatat gttgtacact tataccgttc
     5761 cggttcctcc gttcgtatat acgtctatgc ttgcgaactt aggagaaatg accaataacg
     5821 gctttgaggt agcgatcagc ggcgatatca tcaagaaaaa agatttctca ttaaccgtgg
     5881 gtacgaatct gtctttccag aagaataagc ttaaatcatt aagtggtaca tatatggggt
     5941 cagagtttac gactagtaaa tatatccaag tatcggcggt gaacgctcct agcttaaccc
     6001 agtatgcggg tgttacttat ttgacggagg gacaaccctt aggcgtattc tatattcctc
     6061 attgcaacgg attggtagag aaggaagatg gtaagtttgt ttatgatatc gcggatctgg
     6121 atggcgatgg caaagtggac ttatcggata gcggtgaccg ttatatagcg ggtcaagcgt
     6181 taccaaaggt atatatgggt ggctttgtta atatgcgata taaagatttt gatctggcgg
     6241 ttcaattaaa tggggcgttc gggcataaaa tctataatgg tacaagtttg acgtttaata
     6301 atttatcatt gtatccaacc tataatatat tggatggggc gttggataag cggatatacg
     6361 acatcaagat ttctgattat tatctggaaa atggtaacta tgttaatatc gagtatatta
     6421 cgttaggtta taatattccc gtcaagaaac tgaagattga gaagtattta aaatccttgc
     6481 gtttggcgtt ctctgttaac aatgtcgcga ccatcacagg ttattctggt atgacgccgc
     6541 ttatcaactc ggcgaatgtg gcgtctaaat cttctgtttc gggtacgttg ggtgtggatg
     6601 ataaattgat ttatccgttg agccgtactt attcactctc actgggtgtt aaattctaat
     6661 tgttaatctt ttaatacgta ttgtcatgaa aaaagtattg gtgagctcca tgctgatttt
     6721 aggtggttta ttctccgctt gttccggatt tttggatgag gatcccaaga gtaagatacc
     6781 ggaagaagaa gcttataaaa gtgagaaatt ggtgtatgta aatacgatcg ctacgattta
     6841 tacctcattt gggaatcggt tatatggaag tacggataat gtgcatactt tacaagagtt
     6901 ttcttccgat gcttggatat tgccgggaag acaaggcgac tgggtagatg gaggtaaatg
     6961 gcaatccttg tttttgcata attatggtcc gggtaacgct acgataaaga gtacttggaa
     7021 tgcgctatat acgattatcg gtaactgtaa tacctcgatc gataatctgg agaccttcat
     7081 tcaagcgggt ggggagagct atctgcaaga ttatcaatat gaggctcgtg cggtgcgtgc
     7141 gattctgtat tatcatttgg tcgatttatt cggtcgtgta cctctggtta cttcttcgaa
     7201 gactgtgatg gcggatgtga atcaatcttc gagaagtgag gtctatcagt ttattgtgga
     7261 tgagttgacg gattgcattc cccatttgcc cagtggaaaa tgccagaata tgggcaagta
     7321 ttatggccgg gtgaccaagg ctgtggggta tatggcgatg gcgaaagtcg ctattaatag
     7381 tcctatcttg tcaaaagatg attggaatga tggttctttg gtgggtggta tcgctaaagt
     7441 ggcgccgtat gtaaaccaag cgggcaaaaa tattaagatc gcgttggatg gtacgactcg
     7501 tgacgcttgg gagacggttc tttattgtca gaaacagata gaaaaggagg gatatagtct
     7561 acaacccaac ttctcccaga atttttccaa gacaaacgat agttcggtag aaaatatctg
     7621 gacccaaccg agtgatggta ctacctataa agtgagcgat tataatccga ctcgtacatt
     7681 acatgcggcc cacgcatccg cttatggctt gcaaggttgg aatggtgcct gcgctaccgt
     7741 agaacagatg aaagttttca agtacggtac ggatgaacaa gatccccgta tggatatgac
     7801 gttcttttat ggaccggtgt tcgtggatgg caagccgata gatgcgggtt taggcgatgg
     7861 agctcagtta tgctataacc caatggatgt ggttgttgat tttaaggagg atgtaccgaa
     7921 ccagatatta aaatttgcgg gagcccgtat gtctaaatat gaggtggata atacgacttc
     7981 ttcttatttg aatcataata atgataaggt gttctggagg tatgcagatg ccttgttatt
     8041 ggcggctgag gcgaaagtcc gtatgggaca aagcggtgat gcggaagtga atgagattcg
     8101 tgaccgtgta caagccggac agaaaagtaa cgtgactttg caagatatct tggatgaacg
     8161 catgttggaa ttctcttatg aggggatgcg tcgtcaggat caaatacgtt tcgggactta
     8221 tacggaacct acgactgatc gttatgcggg agtgcatcat aatgtcgcca ctggcgatta
     8281 cgtagtggat aataccggtt ttacaaccgt tttcccgatc cctacttctg tgcttgagct
     8341 aaatacaaaa ttaacacaaa atccgggtta ttaattcttt aaatttagag gatatgagat
     8401 gtaagtattt attgttatat gggctattgg ctgtcttacc attctcggcg caggccggat
     8461 ataaaaagat agcgaatggt atattggtca gcttgccgga aggcgagctg aaccaatcga
     8521 aaacggttcg tttgttggtt gtgaatgatg aggttattca agtgacggca agcccggagg
     8581 ctaagattca ggataagcag agtttagtcc gtgtcgctcc ggtaaaggcc ccggtaaaat
     8641 ggaatgtcga atcgacttcg gattccgtat ttctgaatac tggtaaatta cgtgcggccg
     8701 tcagtcttgt tacgggagaa gtgacattct atgatatgtc gggtaagcta atattgcgag
     8761 aaagtaacgg tggacggcat tttacgccga tagaggtgga aggtcgcaaa ggctatacga
     8821 ctcgccagca atttaattcg ccggaagatg aggctttcta tggattgggg cagcaccagt
     8881 cggatgaatt taattataaa tcgaaaaatg aggagttgta tcagtataat accaagatat
     8941 cggtgccttt cgtggtttct tccaagaatt atggtgtctt attcgataac tattcttatt
     9001 cccggtacgg tgatccacgc ccttattcga acttggatat ctttaagttg tacgataaga
     9061 atgggaaaga gggaggtttg accgctactt attataaaaa taatggattg gaggtctttg
     9121 cggaacgtca agagtccaga attgattacg agaccctgtt tacgcaccaa cctcttccga
     9181 agacgtttga ttttaaggga gagacgtttg ataaattccc ggaaggattc cgtttcagga
     9241 acagcttggt cgtttgggaa ggtgagatcg aaccgaaaga aagtggtgtt tatcatttta
     9301 agttattcta tggagcgtat acgaaagtct tcttggataa taaactggtg gtagaagaac
     9361 gttggcggcc ctcttggaat cctaatagcg tgaaattcac ggccgatttg caagcgggaa
     9421 agaaagtccc agtgcgtatc gaatggcgtg agggagccgg ctcttatatc gggttgaaag
     9481 tattgtctcc tcgtccggaa gaagaagtag ggcgattgtc tatgtggtcg gagatgggaa
     9541 atgatataga ttattatttt attcatggtg attcgatgga cgaggtaatc tcaggctatc
     9601 ggtatgtcac cggtaaatcg ccgatcatgc ctgcttgggc gatgggcttt tggcaaagcc
     9661 gtgagcggta taaaacgcaa gatgagatat tgacggcctt gcgtgagctc cgaaaacgta
     9721 aaatgggtgt ggataatatt gtcatggact ggcagtactg gaaaactgat tcatggggaa
     9781 gccatgagtt tgacccggca cgtttctctg atccgaaagg tatggttgat gcgattcatg
     9841 atttgaatgc ccgtttcatg atctctgttt ggccgaaatt ttatcctacc acaaagaatt
     9901 ataaagaatt ggcggctaac ggatgggttt acctgcaagc ggttaaggat agcatccttg
     9961 attttgttcc acctggattc gtggctacat tttatgatgc ttatgccccc ggtgcccgta
    10021 agttattctg gaaacaaatg aatgataacc tatatcgttt gggtgtggac gcttggtgga
    10081 tggacgcttc cgaaccgaat attaaggatt gtacaccgat gtcttaccaa aaggcgttga
    10141 ccggcccgac agctttaggc ccttcagctc aatattataa tacgtatgcg ttggtgaatg
    10201 cgcaggctat ttatgagggg caattgaagg aaaatccgga tgatcgcgta tttttgttga
    10261 ctcgttccgg attcgctggc ctacaaaggt attccaccgc ttcttggagc ggagatatcg
    10321 gtactcgttg ggaggaattg aaagctcaga tttctgcggg gttgaacttc tcaatctccg
    10381 gtatacctta ttggacaatg gatatcggtg gcttctgcgt ggagaaccgt tatcgtacag
    10441 gacagcttat ttatgacaag accggtgttg agaatgacga cttgaaggaa tggcgggaac
    10501 tgaatgcccg ttggtatcag tttggcacat ttaccccttt gtaccgtgcg catggacagt
    10561 ttccattgcg tgagatttat aatatcgccc cggaagatca tccggcctat cagacgatct
    10621 tgtattataa tcaattgcgt taccgcttga tgccttatat ttattcgttg gcaggtaaga
    10681 cgtattttga tgattatacg attatgcgtc cattggtgat ggattatgcc tccgacttgg
    10741 ctgtccggga taattctacc caatatatgt tcggcccctc tatgatgatc gccccggtat
    10801 atacctataa agcgacttcc cgtgaggtgt atttcccgaa aggaacggat tggtatgatc
    10861 tatatacggg taaacgttat aaaggtggcc aaaagcagga ggttgaggct ccattcgaac
    10921 gtatgccgat atttgctccg tcaggtggta tcttattata tggtccggag atcacttatg
    10981 taaatgagaa aaaaccggaa gtgatagatg tctatattta tgccggaaag gatggctcct
    11041 tctatctata tgaagatgaa ggtacgaaca ataattacca gaaaggaact tattcgaaga
    11101 tcgattttaa ttatagcgat gcgacgaata ctttgacaat cggtagtcgt gaaggctctt
    11161 atcccgggat gttatcagag agaactttca atattattta cgtaagcccg aatgctcctg
    11221 cgggatggga taataagggt aagcctgcaa aggtaattga gtacaaaggt gaacaaattt
    11281 ctgtcaagtt ataagattct ttagactgaa acggcctcct ccgcaatttc catgatagta
    11341 tagcgtgagg gggctctatt tatagtctca ac
//
LOCUS       DBMDTB010000114        11359 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_1707_length_11359_cov_11.361165, whole genome shotgun
            sequence.
ACCESSION   DBMDTB010000114 DBMDTB010000000
VERSION     DBMDTB010000114.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 11359)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 11359)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11359
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1707_length_11359_cov_11.361165"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..926)
                     /locus_tag="ACZPB4_14460"
     CDS             complement(<1..926)
                     /locus_tag="ACZPB4_14460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HIR1099453.1"
                     /translation="MDYIAHTLPNGLRMVHLPVNSPVSYCGFAVNAGTRDENEDEFGL
                     AHFVEHMIFKGTEKRKAWHILNRMENVGGELNAYTTKEETFVYSIFMEEDFGRAFELL
                     TDLVFHSQFPKQEIEKEVDVILDEINSYEDSPSELIFDEFENLLYKGHALGHNILGDE
                     ESLLRFDSESGRSFMRRFYAPENMVFFSMGRKDFKKILKSAESALSDISFPMAERIRK
                     APDPIEACVRQIHKDTHQAHVLIGGRAFSMHDKKRIPLFLLNNILGGPGMNNRLNVSL
                     REKHGLVYNVESNITSYTDTGLASIYFGTDPK"
     gene            1101..2669
                     /locus_tag="ACZPB4_14465"
     CDS             1101..2669
                     /locus_tag="ACZPB4_14465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HIR1099454.1"
                     /translation="MGNIVRKLPIGIQSFDKLRTENYLYVDKTEFIYQMAYQGVPYFL
                     SRPRRFGKSLLLSTFKAYFEGKKELFRGLAIEKLETEWKEHPVLHFSLNAELYDSRKA
                     LENMLERQLREWEKIYDTGGEGITYSGRFMTIIRRAAEITGRKVVVLIDEYDKPLLRN
                     LHNEELQNEFRELLTAFYTVLKDADPWLRFVFITGVTKFAQVGIFSNLNHLNDISLAP
                     QYTALCGMTLPEIEATFQPELHALAEANKLSYEDTIEKITRRYDGYHFDFRSGIALYN
                     PFSVLNVLSKQVFYYYWFASGTPTFLAEMLRKTNYDIRELDGIEVSEVSLSDDRANIN
                     NPVPMIYQSGYLTIKSYDERFRLYTLGYPNEEVKYGFLNFVASMYAHLPETETPFYIG
                     KFIQELESGNTEAFLTRLKAFFADIPYELNDRTERHYQVVFYIVFKLLGQFTEAEVRS
                     AQGRAEAIVKTPRYIYVFEFKLRGTAEEAIRQIDDRGYLIPYTADEREVVKVGVAFDA
                     ATRNLGEWLIEKTL"
     gene            2674..4320
                     /locus_tag="ACZPB4_14470"
     CDS             2674..4320
                     /locus_tag="ACZPB4_14470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HIR1099455.1"
                     /translation="MRNMKIATCLLTITSLVLSACGGGGNDIEKAKSLATTEHLKQYT
                     EAISHDSCQGRKPFSEGADRAVNYIARQMKEVGLKPINGDSYLQQVNIISSRTQCPKP
                     MVLSTPEGKISLDWLEGYTAFSARIEPEIDIDNAELVFAGYGIVAPEYGKNDFEGIEN
                     PQDKVAVVIVNDPGLGSDNTDYFNGDIMTYYGRWMYKFEEGARQGLKGVLIIHEDRGA
                     GYPWSVVRASAQSKMYVDSDSDAYHCPLNGWIQFNAAKQLLADNGYDIDQLIEQSKSP
                     DFKPISLKSTVTVSMRNTFDRQQSPNVIGYIPGSGNTDESVIYLGHWDHLGYGAPING
                     DSIINGATDNAVAIAWMLEMARCFNALKEKPRRNIVFLSPTCEETGFLGTKYYVEHPL
                     FPIDKIAAVINLDVFPLWGENNDVTITGYGNSELDDTLAELAKKYNRYIMPDPDAYNG
                     MFYRSDHFPFVQKGIPAMFAKGWNDNRKQGKEWAKEHIARYWAETYHKPTDQTHPDTD
                     DYSGLLQEVQLFFDLGYKLAQDTGYPKWKPKSEFANVLKR"
     gene            4415..5026
                     /locus_tag="ACZPB4_14475"
     CDS             4415..5026
                     /locus_tag="ACZPB4_14475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HIR1099456.1"
                     /translation="MVNENITSLLEQEAEAVRNIPVTPGYEEAVSLIVKHVHDLGGKL
                     IMSGMGKAGQIALNIATTFSSTGTPAFFLHPSEAQHGDLGIVCKNDIMLLISNSGKTR
                     ELVELVDLTRGLVPDMKFIVITSNPDSPLAAEANVCLLTGAPKEVCPLGLTPTTSTTV
                     MTVIGDILVVGTMKRIHFTNKDYAKRHHGGYLGSKSRELSKNE"
     gene            5044..5973
                     /locus_tag="ACZPB4_14480"
     CDS             5044..5973
                     /locus_tag="ACZPB4_14480"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase family protein"
                     /protein_id="HIR1099457.1"
                     /translation="MRKVFGIGETILDIIFRNDQPQKAVPGGSVFNGLISLGRLNVPV
                     SFISELGNDRVGDMIRDFMEDNHITTEFVDRFPDGKSPISLAFLDDDKNANYIFYKDY
                     PAQRLEVPLPKIEKDDIFVFGSYYSLNPVLRTRMVEFLQYAQERKAIIYYDPNFRKAH
                     AHEAIRLMPTVLENLEFADIVRGSDEDFQNLYGKSDAQEVYKEHIQFYCDRFLTTHGA
                     NGVNLHTRNFTRHFDSPQIQPLSTIGAGDNFNAGIIYGLLKYDVRHADLPSLDQDTWG
                     KIIRCGMDLASEVCQSYDNYISKEFAAKYVSQS"
     gene            6047..7102
                     /locus_tag="ACZPB4_14485"
     CDS             6047..7102
                     /locus_tag="ACZPB4_14485"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004721 - phosphoprotein phosphatase
                     activity [Evidence IEA];
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase"
                     /protein_id="HIR1099458.1"
                     /translation="MLGKILSLFASVILLVGCSSNAPDIRAICLRDDIGNYVIKWETD
                     PVMEGIVKMTVSDNPDLFTNESPIIYANIKDGVATYITNDNISRKYFRLSFNDKYARI
                     IGARSAVMDSVQNFRDLGGYTSTNGKTVKWGKVFRSGELSSLSEWDSIRLDNLGIKTI
                     IDLRTNQETLTAPIKYTKANILQIPISVGKIADAPQRVIEGRMRKGDAGVYMEDEYLQ
                     FVTDNTDQFAKVLEQFQNEDNYPILISCSYGKDRTGFLTAMLLAALDIPRDAIMEDYL
                     TSNQYIDTSHLADIVKHLSTDAQESITVFLTANEGLMDLAFHKIKKEYGSTEKYLSKG
                     LRLTDKKRERLKDILLY"
     gene            complement(7173..8717)
                     /locus_tag="ACZPB4_14490"
     CDS             complement(7173..8717)
                     /locus_tag="ACZPB4_14490"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: protein motif:HMM:NF012318.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like serine protease"
                     /protein_id="HIR1099459.1"
                     /translation="MKKTFLIISVLLGILFYPVNAQQRIVEGSNINISEVPWQVAIQT
                     KGVFNGGGSILAPNLILTAAHVVEKYTAKEVKVGVGSSKYSNIGANWYSVSNIVYHPS
                     LDIALLILSRPLSYSTNVKAIDILSANKASYYNVGNILRVTGWGITFLVIDDPFKEWK
                     MSDDLKKVDLPIVSNSTIGAANSFVITYDGKHSPSKGDSGGALTIWDSSLQRHVVIGT
                     VHGNPSTQRAYCAYVRSSSFLDFLLPYYPISITGGSDQVCSSSTFSVSYPNSTVTWSC
                     TGPLRITSQSNTSCTVSSTGNGPAVLKATIKSGNYTKTVERKVISGGYTSCMITYRNT
                     VNGNDTWCTSHSGNIFTIESDYNLSSYEVRLLRYPGLNVVMTRTASKGDNDLTNMLSP
                     GWYTMEARLLGCKNGDWVTTGEVEAVDCSSNYSFSLTPNPATSLVTLTLNDVNTPSPR
                     MEPMFTTENGGEYEVQIWSETSLLKQFTFDRPIVEIPVSELRSGRYFVLVFVNGKKLT
                     QQLIIK"
     gene            complement(8739..9095)
                     /locus_tag="ACZPB4_14495"
     CDS             complement(8739..9095)
                     /locus_tag="ACZPB4_14495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099460.1"
                     /translation="MKKERMIIAFLSLLFLLPGCKEEKTQSVFDADEFDCVGWPHIRK
                     VTITNVNCEAEGIFLILEDSLVYCDDEIVIPYKNHYGKRLEVGFCFGDRKRYPLCKSD
                     SSVIDISVLSVRELNE"
     gene            9819..>11359
                     /locus_tag="ACZPB4_14500"
     CDS             9819..>11359
                     /locus_tag="ACZPB4_14500"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003724 - RNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0000027 - ribosomal large subunit assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HIR1099461.1"
                     /translation="MGYESPMPVQEEVIPFLLGEDNDVIALAQTGTGKTAAYGLPILQ
                     KINVSQYQPQALILCPTRELCLQIADDLNDYSKYIDNLKVLPVYGGSSIESQIKTLKR
                     GVHVVVATPGRLIDLMNRKTVDLSNVKNVILDEADEMLNMGFTDSINEILAAIPENRN
                     MLLFSATMPKEIASITKKYMKDPKEIVIGRKNEGNKNIRDIYYMVRAQDKYLALKRLA
                     DYYPNIYGIIFCRTRKETQEIADKLIQDGYNADSLHGELSQAQRDYVMQKFRIKNIQL
                     LVATDVAARGLDVDDLTHVINYGLPDEVESYTHRRGRTGRAGKTGIAISICHVREKGK
                     IREIERIINKKFDRGEMPTGEQICEKQLFNLVDQIEKVKVNEEEIASLMPSIYRKLEW
                     LDKEDIIKRVVSLEFNRMIDYYKDNDDIEVVDENAPRERGKRGGRGEAEEGYTRFFIN
                     FGKTDELTPPQLIELVNKCVPGKVRIGRIDLRDNFSFFEVEEGEANRVMDSMNGFEVD
                     GRRISV"
BASE COUNT         3357 a         2685 c         2504 g         2813 t
ORIGIN      
        1 ttcttcgggt ctgtcccgaa atagatactg gctagtccgg tatcggtata agaggttata
       61 ttggattcta cgttatagac caagccatgc ttttcccgca aggagacatt caagcggtta
      121 ttcatgcccg gaccacccaa aatattattc aacaaaaata aaggaatgcg ctttttatcg
      181 tgcatactga aagcccggcc accgatcagt acatgggctt gatgggtatc tttatggatc
      241 tggcgtacgc aagcctcgat ggggtccgga gctttccgga tccgttcagc catcgggaaa
      301 gagatatcgc ttaaagcgga ttccgctgat ttcaagatct tcttgaagtc ttttcgtccc
      361 atcgagaaga acaccatatt ctccggggcg taaaaacgac gcatgaaaga acgaccggac
      421 tcggagtcaa agcgaagaag agattcctca tcccctaaga tattatgccc gagagcatga
      481 cccttataaa gcaagttctc aaactcgtcg aatataagtt ccgaaggact atcctcatac
      541 gaattgatct catccaagat gacatctacc tccttctcga tctcctgttt ggggaattgg
      601 gaatggaaaa ccagatcggt caatagctca aacgcccggc cgaaatcttc ctccataaaa
      661 atggaataaa caaaagtctc ttccttcgta gtataggcat tcaactcccc tcctacgttc
      721 tccatacggt tcaggatatg ccacgctttc cgtttctccg tacctttgaa gatcatgtgt
      781 tcaacgaaat gcgccaagcc aaattcatcc tcgttctcat cccgtgtacc ggcgttcacg
      841 gcgaaaccgc agtaagagac cggggaatta accgggagat gtaccatgcg aagaccattc
      901 ggcaatgtat gagcgatata atccattttc cttcttgttt gtatcagccc gcaaaggtac
      961 gaaagacttt ccggaaaaac atgtacgtct ttttcaaaaa acatgtacgt gtttccggaa
     1021 aaagacatac gtgttttttt cgatctattt gcctccttgg aaaaaatacc tacatttgtg
     1081 taaattaaac agataaggct atgggaaata tcgtccgaaa attaccgata ggcatacaga
     1141 gttttgacaa actacgtaca gagaactatt tgtatgttga caagaccgag ttcatttatc
     1201 aaatggcata ccaaggtgtc ccttatttcc taagccgccc ccggcgattc gggaaaagct
     1261 tgctgctatc gacattcaag gcttatttcg aggggaagaa agaattgttc cgaggattag
     1321 ccatagagaa actagagacc gagtggaaag agcatccggt acttcatttc agcctcaacg
     1381 ccgagttgta cgatagccgc aaggcattgg agaatatgct ggaacgccag ttgagggaat
     1441 gggaaaaaat atatgatacc ggaggagagg gtatcaccta ttccggacgg ttcatgacca
     1501 tcatacgaag ggcggcggag ataaccggaa ggaaggtggt cgtactgatc gacgagtacg
     1561 ataagccatt acttaggaac ctgcacaacg aagagctaca gaacgagttc cgggaattat
     1621 tgaccgcctt ctatacggtc ctcaaagatg ccgatccttg gctgcgcttc gtattcataa
     1681 ccggtgtcac caagttcgcg caagtcggta ttttcagcaa cctaaatcat ttgaacgaca
     1741 tcagcctagc cccgcaatat acggcccttt gtggcatgac attgcccgag atcgaggcga
     1801 ctttccagcc ggagcttcat gccttggccg aggcgaataa gctttcatac gaagatacca
     1861 tcgagaaaat tacacgccgg tacgacggct accattttga tttccgcagc ggtatcgccc
     1921 tttataaccc gtttagcgta ttgaacgtgt tgagtaaaca ggtcttttac tactattggt
     1981 ttgcttccgg taccccgaca ttcttggcgg agatgttacg gaaaacgaat tacgatatac
     2041 gggagctgga cgggatagag gtatccgagg tatccctttc ggacgatcgg gcgaacatca
     2101 ataatcccgt gcccatgatt tatcaaagcg gatatttgac aatcaaaagc tacgatgaac
     2161 gttttcggtt atatacgtta ggatacccga atgaggaagt taaatatgga tttttgaatt
     2221 ttgttgcctc catgtatgcg catttaccgg aaaccgagac tcccttttat atcggaaagt
     2281 tcattcaaga gctggaaagc ggaaacaccg aggctttcct cacccgccta aaggctttct
     2341 tcgccgacat accctacgag ctgaatgacc ggaccgagcg tcattaccaa gtggtcttct
     2401 acatcgtatt caagctacta gggcaattca ccgaggccga ggtacgttcg gcccaaggac
     2461 gtgccgaggc cattgtaaaa actcctcgct acatctacgt attcgagttt aagctgagag
     2521 gtacggcgga agaggcgatt cggcaaatcg acgatcgagg ctatctgatt ccttatacgg
     2581 ccgacgaacg ggaagtagtc aaagtggggg tcgctttcga cgcagccact cgcaacttag
     2641 gtgaatggct gattgaaaaa acattgtaat tctatgagaa acatgaaaat agcaacctgt
     2701 ttactaacga tcacctcctt ggttctttcc gcctgtggag gaggaggcaa cgatatagag
     2761 aaagcgaaaa gccttgcgac cacggaacat ctaaagcaat acaccgaggc catctcgcat
     2821 gactcctgcc aaggccgtaa accattctcg gaaggggccg accgtgcggt gaactatatc
     2881 gcccgccaaa tgaaggaagt cggcctgaaa cccatcaacg gagattctta tctccaacag
     2941 gttaatatca tatcctcacg tacgcaatgc ccgaagccga tggtcttgag taccccggaa
     3001 ggaaagatct cattggattg gctagagggc tataccgctt tctccgcacg gatcgagccg
     3061 gagatcgata tagacaacgc ggaactggta ttcgccggct atgggatcgt agcccccgag
     3121 tatgggaaaa atgatttcga gggaatcgag aacccgcagg ataaagtagc ggtcgttatc
     3181 gtaaatgacc cgggactcgg aagcgacaac acggattatt ttaacggtga tatcatgacc
     3241 tattacggcc gttggatgta taaattcgag gagggcgccc gacagggatt aaaaggagtc
     3301 ttgatcatcc atgaagaccg gggagcgggc tacccttggt cggtcgtacg agcttccgcc
     3361 caatctaaga tgtatgtgga cagcgatagc gatgcttatc attgcccgct aaacggctgg
     3421 atccaattca atgccgccaa gcaattgcta gccgataatg gctacgacat tgaccaacta
     3481 atcgagcaat ctaaatcgcc ggacttcaag cccatctcct tgaaatctac ggtaaccgtc
     3541 tcgatgagga acaccttcga ccgccagcaa agccccaacg taatcggtta tattcccggt
     3601 agcgggaaca cggatgagag tgttatttat ctaggccatt gggaccatct aggctatgga
     3661 gcaccgatca acggcgacag tatcatcaac ggcgctaccg ataacgccgt agccatcgca
     3721 tggatgctcg agatggcacg ttgtttcaat gccttgaaag agaaaccccg ccggaatatc
     3781 gtcttcctct cccctacttg cgaggagacc ggattcctcg gtacgaaata ctatgtggag
     3841 cacccgttgt tcccgattga taagatagcc gccgtaatca atctggatgt cttcccgcta
     3901 tggggcgaga acaacgatgt cacgatcacc ggatacggca actccgagct ggatgatacc
     3961 ctagccgagc tagcgaagaa atacaaccgt tacatcatgc ccgaccccga cgcttataac
     4021 gggatgttct atcgctccga ccatttccct ttcgtacaaa aaggcatccc ggccatgttc
     4081 gccaaaggtt ggaacgacaa ccgcaaacag ggtaaggagt gggccaaaga gcatatcgca
     4141 cgctattggg cggaaactta ccacaaaccg accgaccaga cccatcccga cacggatgat
     4201 tacagtggtc tgttacaaga agtacaatta ttcttcgacc tcggttataa actggcgcaa
     4261 gataccggat acccgaaatg gaagccgaag tccgaattcg caaacgtctt aaaaagataa
     4321 attgtctgaa atagatgatg ccaatatcag taaatataaa tactttcgcg atcgttattc
     4381 aggcaggaat gccgtaaaac aatcaatcaa caatatggta aacgaaaata tcacctcttt
     4441 attggagcag gaagcggaag cggttcgcaa catacccgtt acgcccggat atgaggaagc
     4501 ggtatcgctt atagtgaaac atgtacacga cctaggtgga aaactgatca tgagtggaat
     4561 gggtaaagcc gggcaaatcg ccttgaatat cgctaccacc tttagctcga ccggtacacc
     4621 tgcttttttc ttacatccca gcgaggcaca acacggagat ctgggaatcg tatgcaagaa
     4681 cgatatcatg ttattgatct ccaactcagg aaagacacgt gaactggtgg aattggtaga
     4741 tctcacgagg ggtttggtgc cagacatgaa atttatcgtt atcaccagta acccggatag
     4801 tcctctagcc gccgaggcga acgtatgcct gttgaccggc gctcccaagg aagtttgccc
     4861 gttaggcctt acgccgacta cctccacgac cgtcatgacg gtaataggcg atatcctcgt
     4921 ggtcggaacc atgaagcgta tccatttcac caacaaggat tacgccaagc gccatcacgg
     4981 gggctactta ggctccaaga gccgtgagct aagcaagaat gaataacaaa ccagtatata
     5041 gtcatgagaa aagtctttgg tataggagaa accatcctcg atatcatttt taggaacgac
     5101 cagccacaga aggccgttcc cggtggttcc gttttcaacg gattgatatc attaggtcga
     5161 ttgaatgtcc ccgtatcctt tatcagcgag ctgggcaacg accgggttgg cgacatgatt
     5221 cgggatttca tggaagataa ccacatcact accgagttcg tagaccgttt ccccgatggg
     5281 aaaagtccta tatcactcgc ttttctggac gacgataaga acgctaatta tatcttctac
     5341 aaggattacc cggcgcaacg gctggaggtg cccctgccta agatcgagaa agacgatatt
     5401 ttcgtgtttg gctcttatta ttccctgaac ccggtcttgc ggactcgtat ggtagaattt
     5461 ctgcaatacg cccaagaacg gaaagcgatc atctattacg atcccaattt ccgcaaggca
     5521 cacgctcatg aggcgatccg cctcatgcct accgtactgg aaaatctgga attcgccgac
     5581 atcgtccggg gctcggacga ggacttccag aacctttatg gcaagagcga cgcgcaggag
     5641 gtttacaaag agcatattca gttttattgt gatcgtttct taacaactca cggggcaaac
     5701 ggagtcaatc tccacacccg taatttcaca cgacatttcg attccccgca aatccagccg
     5761 cttagtacca tcggcgccgg cgacaatttt aacgcgggta ttatctacgg acttctaaag
     5821 tatgacgtac gccatgccga ccttccctct ctggatcagg atacttgggg aaaaatcatc
     5881 cgctgcggaa tggacctcgc ctccgaggtt tgccaaagct atgataatta tatatccaag
     5941 gagttcgcgg cgaagtatgt tagtcagtct taaatatcat taatgaagaa gcgggaaaaa
     6001 cttgttttac tatctttgta aggaaagctt attataatag aagacaatgt taggaaagat
     6061 tctctctcta ttcgccagtg tgatcctgtt agtgggttgt tcctctaatg cgcccgacat
     6121 acgagcgatt tgcctacgtg atgacatcgg aaattacgtg ataaaatggg aaaccgatcc
     6181 ggtaatggag gggattgtca agatgaccgt gtccgacaac ccggatcttt tcaccaacga
     6241 gtccccgatc atttacgcca acatcaagga tggcgtggct acttacatca cgaacgataa
     6301 tatatcacgt aagtatttcc gcctttcttt taatgataaa tacgcacgga tcatcggggc
     6361 acgctcggcg gttatggata gtgtacagaa tttccgggat ctaggcggtt atacctctac
     6421 aaacgggaag acggtgaaat ggggcaaggt atttcgctcc ggcgagttaa gcagcttgag
     6481 cgaatgggac tccatccgat tggataatct agggatcaag accatcatcg acctccgtac
     6541 gaaccaagaa accctcaccg cccctatcaa atatacgaaa gcaaatatcc tgcaaatccc
     6601 tatctcggtc ggcaagatcg ccgatgcccc ccaacgtgtt atcgagggac gaatgcggaa
     6661 aggagacgcc ggggtatata tggaagacga gtacctgcaa ttcgtgacag ataacaccga
     6721 tcagttcgcc aaggtactgg aacagttcca gaacgaggat aattacccca ttctcatcag
     6781 ttgttcctac ggaaaggatc gtaccgggtt tctcaccgcc atgttactcg ccgccttgga
     6841 tattccccga gatgccatca tggaagacta cttgacatcc aatcaatata tcgatacgag
     6901 tcatttagct gatatcgtga aacatctctc cacagacgcc caagaaagca ttacggtatt
     6961 ccttacggcc aacgaggggc tcatggacct agctttccat aaaatcaaga aagagtacgg
     7021 ttccaccgag aaatatttgt cgaaaggatt acgtcttact gataagaaac gtgaaaggct
     7081 caaggacata ttactttatt aagaaaaaga gccacccgga aaagattcac ttacccgatg
     7141 gctctcggta attctccacg tttatgcctg ttctatttga taattaattg ttgagtcagc
     7201 ttcttgccgt tcacaaaaac cagcacaaaa taccttccac ttctcaattc cgatacaggg
     7261 atttcaacta taggacgatc gaaagtaaat tgtttcaaca agcttgtttc cgaccagatt
     7321 tgtacttcat actcacctcc attttctgtc gtaaacatag gttccatacg tggactaggc
     7381 gtatttacat catttagagt taacgttact aggctggtgg cagggttcgg tgtcaaagaa
     7441 aagctataat ttgaggagca atccacagcc tctacctcac cagtagttac ccaatctcca
     7501 ttcttgcatc ccaacaaacg agcttccatt gtataccaac ccggagagag catattagtc
     7561 agatcattat cacctttcga ggcggtcctc gtcataacca cattcaaccc cggatatctc
     7621 agcaaccgaa cctcataaga actcaaatta taatcagact cgatggtgaa gatatttccg
     7681 gaatggctcg tacaccatgt atcgtttcca ttcacagtgt tccgataggt gatcatacaa
     7741 gaggtatagc ctccactaat tactttccgc tctacggtct tcgtataatt tccgctcttg
     7801 attgtggctt tcaatacggc aggtccgtta ccggtagaag agaccgtaca agaagtattg
     7861 ctttgcgagg ttattcgcaa aggccccgtg catgaccaag taactgtgga gtttggataa
     7921 cttacagaga atgttgaaga agaacagact tggtctgaac caccggtgat ggatatggga
     7981 tagtaaggaa ggaggaagtc gaggaaggag gaagatcgaa catacgcaca ataagctctc
     8041 tgagtactag gatttccatg tacagttcca attacaacat gtctctgtaa agaagaatcc
     8101 caaattgtca atgctccacc actatcacct ttagaaggac tatgcttacc atcatatgta
     8161 ataacaaaac tattagcagc tcctatagta gaatttgaaa caataggaag atctaccttt
     8221 tttaaatcat ctgacatttt ccattcttta aaaggatcat caatcacaag aaaagtaatc
     8281 ccccaacctg taactcgaag tatatttcct acattataat aagaagcctt attagctgaa
     8341 agaatatcta tagcttttac atttgtagaa taagacaaag gcctagacaa tattaataaa
     8401 gcaatatcca aagaagggtg ataaacaata tttgaaacag aataccaatt cgcaccaata
     8461 tttgaatatt tagaactacc aactcccact ttaacctctt ttgcagtata tttttccacc
     8521 acatgagcag ctgttaaaat caagtttgga gccaatatag accctcctcc gttaaaaaca
     8581 cctttcgttt gaatcgcaac ctgccaagga acctctgata tattgatatt agatccctcc
     8641 actattcgct gttgagcatt tacaggataa aacaatatac ccaataaaac actaataatt
     8701 aaaaaagttt ttttcataat acaatcatat taaaaagttt attcattcaa ttctcgaaca
     8761 gaaagtacag aaatatcaat tactgaggaa tccgatttac acaatggata tctctttcta
     8821 tccccaaaac aaaagcctac ttctaaacgt tttccgtagt gatttttata aggtataact
     8881 atctcatcat cacaataaac taaagaatcc tctagaataa ggaatattcc ctctgcctca
     8941 caatttacat ttgtaatagt aacctttcta atgtgtggcc aaccaacaca atcaaactca
     9001 tctgcatcaa agacactttg tgttttctct tccttgcatc ccggcaacag gaaaagtaaa
     9061 ctcaaaaaag caataatcat tctttctttt ttcataagct ctctatttta gatttataaa
     9121 cggtaacaaa tcacggcgct tgactcctcc atcatggcaa caagcaggtt catcgggcaa
     9181 gacaggctca agacggtctc aatatataca ttatctacaa tatatacaat gaaaagtctt
     9241 ttaacttttc atttatctta atccatagaa aatctccgtt caaaccgttt ctaacaaact
     9301 gtcacttttt gacacattgt aatctaaagc ctcagagaat cgaatattcc gggacttagt
     9361 acggctcgct cgcaaataag gaagaaatat ttcgcaatca gctattgatt aacaagatac
     9421 caaaaaacgg tctttcgcca cctatcacac ttggaaaagg cactattttc ccccaaagca
     9481 ccactttatc cccttaccct tcggctatat catagtatca agaaaaagga catgtcacga
     9541 tatacgccct atttctatca gaaagatcag acaagagctg tttcgctaac aaataaacga
     9601 cacggttcgc atgcgaccga ggtgcccacc ctctcccaat aggtaaaaac catccgtggt
     9661 tcgctgattt ttagcgaatt tagcataaca atcctataga atccgaatta tttacgtacc
     9721 tttgcggcca ctgaatatta tcatatatac acaatcgcat tttgaaaaca tttgaagaat
     9781 taggagttgc cgcaccgata ttaaaggcaa ttcaagagat gggctatgaa tcgcccatgc
     9841 ccgtacagga agaagtgatt cctttcttac tgggagaaga taacgacgta atcgcattgg
     9901 cacaaacagg aaccggcaag acagccgctt acggcctgcc gatcctgcaa aagatcaatg
     9961 tctctcaata tcaacctcaa gcgcttatcc tttgtccgac acgcgagctt tgcctacaga
    10021 tagcggacga tttgaacgat tattctaaat acatcgataa cctgaaggtt ctccctgtat
    10081 acggaggttc cagtatcgag agccagatca agacactgaa gagaggcgta cacgtggtag
    10141 tggctacccc gggacgtttg atcgacttga tgaaccgcaa gacggttgat ttaagcaacg
    10201 taaagaacgt catcctcgac gaggcggacg agatgttgaa catgggtttc accgacagta
    10261 tcaacgagat cttggcggct ataccggaaa accgaaatat gctgctcttc tccgctacca
    10321 tgccgaaaga gatcgcttct atcaccaaga aatacatgaa ggatccgaaa gagatcgtca
    10381 ttggcaggaa gaacgaggga aacaagaata tccgcgacat ttattatatg gttcgtgcgc
    10441 aggataaata tctcgccttg aaacgtctag ccgattatta cccaaacatc tacggcatca
    10501 tcttctgccg tacccgtaag gagacacagg agatcgccga taaattgatt caagacggct
    10561 ataacgccga ttccttgcac ggcgagctga gccaagcgca acgtgactac gtgatgcaga
    10621 agttccgtat caagaatatc cagttattgg tcgctacgga cgtagccgca cgtggtttgg
    10681 acgtggatga cttaacccat gtaatcaatt acggtctgcc ggatgaggta gaatcttata
    10741 cccaccgccg cggacgtacg ggccgtgcgg gaaaaacggg tatcgctatc tctatctgcc
    10801 acgtaaggga aaaaggcaag attcgcgaga tcgaacggat catcaacaag aaattcgaca
    10861 ggggcgagat gcctaccggt gagcaaatct gtgagaagca attgttcaac ttggtggacc
    10921 agatcgagaa agtgaaagtg aacgaggagg aaatcgctag tttgatgcct tctatctacc
    10981 gtaaattgga atggctggat aaggaagata tcatcaaacg tgtcgtatcc ttggagttca
    11041 accggatgat cgactattat aaagataacg atgatatcga ggttgtagac gagaacgctc
    11101 cccgagagag aggtaaacgg ggtggcagag gcgaagcgga agaaggttac acccgtttct
    11161 ttatcaactt cggaaagaca gacgagctta cgcctcctca acttattgag ttagtcaaca
    11221 agtgcgtacc gggcaaggtt cgtatcggtc gtatcgactt acgtgataat ttctcattct
    11281 tcgaggtaga agagggagaa gccaaccgtg tcatggactc gatgaacggc ttcgaggtag
    11341 acggacgacg tatctccgt
//
LOCUS       DBMDTB010000115        11224 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_1729_length_11224_cov_11.107255, whole genome shotgun
            sequence.
ACCESSION   DBMDTB010000115 DBMDTB010000000
VERSION     DBMDTB010000115.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 11224)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 11224)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11224
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1729_length_11224_cov_11.107255"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..825)
                     /locus_tag="ACZPB4_14505"
     CDS             complement(<1..825)
                     /locus_tag="ACZPB4_14505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008771676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099462.1"
                     /translation="MKKLFIALAAVTLTACVKAPEKTVKVYAWQGEGGNTTEQTLQAD
                     FSKWHAHGVDGMCYNAGHDTEKIQRAAKAAHANGMEYHAWIPAMLQHGLDSTLYAVNR
                     KGESAYSVQAYVPYYKCLCPNQEGTAEFLLNLYGKVADIPEVDYIHLDYIRYVDVILA
                     RGLWEKYGLVMDEEYPTADYCYCDKCVADFKAATGIDIKSVEDPSKCAEWARFRCDLI
                     TKLVNRIADEVHGKGKKVSAAVFPGPDSHAKWMVRQEWNKWNIDAFFPMNYNDFYLE"
     gene            complement(822..3674)
                     /gene="gcvP"
                     /locus_tag="ACZPB4_14510"
     CDS             complement(822..3674)
                     /gene="gcvP"
                     /locus_tag="ACZPB4_14510"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010800225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004375 - glycine dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_process: GO:0019464 - glycine decarboxylation via
                     glycine cleavage system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase"
                     /protein_id="HIR1099463.1"
                     /translation="MDTNKFVNRHVGISAEDIPAMLETIGVKSLDELIDQTIPANIRL
                     KEPLNLPEAMTEREFAEHIAELASKNEVFTSYIGMGWYDTVCPAPIQRNVFENPVWYT
                     SYTPYQAEVSQGRLEALLNFQTVICELTGLPLANCSLLDEATAAAEAVTMFHGSRSRA
                     QVKAEANTVFIDENVFASTLAVIHTRMIPQGIQVVVGDYKKFEFTPDVFAAIVQFPNA
                     DGSIEDYKEFVARAGAAGAKVGVAADLMSLVLLTPPGEWGADVVFGSSQRFGIPMFYG
                     GPSAAFFATKDDYKRTIPGRIIGISKDAYGHPAYRLALQTREQHIKREKATSNICTAQ
                     ALLATMAGFYAVYHGAEGLRNIAGRIHSTAGFLAKELEKLGYTQLNKDYFDTLKIQLP
                     SHVSVNALREIALECKVNLRYFEAGQVGVSIDETTLPTDIGVLLYIFAGAAGKDYMLD
                     ESIPAQTYFDAKFARTSDFLQQDVFKKYHTETELMRYITRLGRKDVSLAQSMISLGSC
                     TMKLNPASTMLPLSRAEFMNIHPYAPEEQVEGYTELIENLSSYLCTITGFKGCTLQPN
                     SGAAGEYTGLRVIRAYQESIGQGHRDIVLLPASAHGTNPASAIQCGYKTVTVKCDENG
                     NIDLEDFRAKAEENKERLAASMITYPSTHGIFEVDIKEMCDIVHACGGQLYMDGANMN
                     AQVGLTNPGTIGADVCHLNLHKTFSSPHGGGGPGVGPICVAEHLVPFLPQHPVLWGSD
                     LNTVSAAPYGSAGILPITYAYIRLLGTEGLETVTKTAILNANYLAAKFKDTYGIVYTG
                     ATGRVGHELILECRTVKERSGIDEGDIAKRLMDFGYHAPTLSFPVHGTLMVEPTESES
                     KAELDRFVEVMECIWSEIKEVEEGKASKEDNVLKNAPHPEYEVTADEWKHAYPRTKAA
                     FPLEWLHDSKFWINVARVDNAYGDRNLIPTLCACEI"
     gene            complement(3687..4325)
                     /locus_tag="ACZPB4_14515"
     CDS             complement(3687..4325)
                     /locus_tag="ACZPB4_14515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008771678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HIR1099464.1"
                     /translation="MITIKSFEVNYFSENTYLLYDDTKEAVLIDCGCLRKEEQKEVSD
                     FIAQNGLTLKRYLCTHLHLDHIFGNEFIHDTYGLSPEAHKADVEGLPSPEEQAKAFGL
                     PMKAKSVPVGKYLVNGEIIKFGKSELAVLSVPGHSPGGVAFYNKKNGFVIVGDSLFAG
                     SIGRTDLWGGNQDILLAAIKDKLLSLPDETVVYPGHGPETRIIDEKLNNPYL"
     gene            complement(4322..5014)
                     /gene="rsmG"
                     /locus_tag="ACZPB4_14520"
     CDS             complement(4322..5014)
                     /gene="rsmG"
                     /locus_tag="ACZPB4_14520"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA];
                     GO_process: GO:0046118 - 7-methylguanosine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HIR1099465.1"
                     /translation="MIDKPINRCPMEQNTEKFSILNSQFSILTSYFPDLTDRQKEQYA
                     ALYDLYTDWNAKINVISRKDIENLYPHHVLHSLGITDMLRFKPGSSVMDLGTGGGFPG
                     IPLAILFPETHFHLVDSIGKKIKVGQAVAEAIGLENVSFRHCRGEEEKQLFDFVVSRA
                     VMPLADLVKIVRKNIKKEQINALPNGLICLKGGELAHEILPFRNQAISMDLKDHFKEE
                     FFETKKVVYVPL"
     gene            complement(5028..5879)
                     /locus_tag="ACZPB4_14525"
     CDS             complement(5028..5879)
                     /locus_tag="ACZPB4_14525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 and DUF4163 domain-containing protein"
                     /protein_id="HIR1099466.1"
                     /translation="MRTHLRESMLALLLIGILATGCDTGTKKASENSITFDSISVEKT
                     YHLLDNPDNPNCNLEIKFVYPRKYSDKEVLKNLQRQFVSSYFGENYEQLSPEEAVRKY
                     TDDYLAAYKDLEEDYKAEVAKSDETPVGSWFSYYEMSSDDIAFNQDDIISYTVSFENY
                     TGGAHGAHSYNNHVVNLKTGKPITEEEIFVDNYQDNLARILVDQIAKQNNVSDAKELE
                     NIGFFSVDEIFPNGNFLVDETGITYSFNEYEIAAYVVGVTNVHLPYKEIRYLLRDDSP
                     ISQLIEN"
     gene            complement(5953..6705)
                     /locus_tag="ACZPB4_14530"
     CDS             complement(5953..6705)
                     /locus_tag="ACZPB4_14530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HIR1099467.1"
                     /translation="MKIIIIEDEAAAYKNIKNLLLQIDPHIEILDHFDTVVDSVTWLR
                     SHPMPDLIFMDIQLADGNSFNIFECVTIEVPIIFTTAYDQYAIKAFEVNSVDYLLKPI
                     TLESMRKALDKYNRLNPVTVRQHISRIDQLVCSSEYLKRILVPFKDRIIPIKTEAIAY
                     FYNTNGESSVVTRERQSYSIGKSLDSLMIKLNPTCFFRVNRQFILSKEVIDSFTIWFD
                     SRLRINLSLPTDEPIFVAKNKAAEFKVWLSSY"
     gene            complement(6723..7829)
                     /locus_tag="ACZPB4_14535"
     CDS             complement(6723..7829)
                     /locus_tag="ACZPB4_14535"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1099468.1"
                     /translation="MKIRHYLLQKPSILIWVSVLSGFFVTSEEIMDCIELSRIRGIDP
                     EIDSILLLIFQCLFFILFTRILLQINVCWQPEKKGHLKQFAYSSLVSVLFSLIVWLGV
                     SPVIRSTNQNIREKYERNEPKENHRFHGKKLFYLFHEPEEAWYNNLFTLFVGIYTFSR
                     IYILAARKEEVERNYEKLKNESLQSQIDALYNQINPHFFFNALNSLHALIVEGQNQKS
                     LAYLSNLSNVFRYILQSEKKELVALKDELSFLETYRFMLSVKYEEKLTFDIQINPAYM
                     SCQLPVLSLLPLIENVIKHNEISARNPMRLSIYSTHEPSLVILNRKQPKLDEVEKVGI
                     GLKNLDNRFALLVKKRIRIEDTDEFFRVSLPLKS"
     gene            8007..10475
                     /locus_tag="ACZPB4_14540"
     CDS             8007..10475
                     /locus_tag="ACZPB4_14540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HIR1099469.1"
                     /translation="MKTALFFKLLFVCLACVAIRPVSAQVLGAGVFELKGQVVDSLTN
                     EPVSFATLRVTRGEEITEPLALLACDIDGYFSVSLPEAGSYYFHMSSIGKIPARRKVS
                     VSAQSPVWNVGKLCMKDDARTLGEVRVSAQRPLVKVDIDKLVYNLEEDPEAKVSNTLD
                     MLRKVPMVTVDGDDNIQLKGNSNFKIYMNGRPSGLLSSNPSTVLKSLPASNIKDIEVI
                     TDPGARYDAEGVSGIINIIMVRRVLDGYTGTVSAEVTTNEAYGGGTFVSLKAGKLGLT
                     ANYNLEYEREPIADITSFRKNLSDDANRYLSQIGEHWEREKMHRGYLEGTFEIDSMNL
                     ISVDANLFRKRQKEFSDLSVEMRDMNRDLIYAYDRFSQNQPVFGSVEVNANYQHETRR
                     KGELLTLSYRFTNDPNDDENRMRITGTSNYSDFLQWDTNRAKTNEHTGQLDYIRPIAG
                     GHDLETGVKYILRQTDSEITQRLYDETSGNWHEPSGSFVDFSHTQHIYSVYLGGTFRW
                     NKLGIKAGVRAEGTSLDVSYSNDLTKDFHSNFVDIVPNVTLSYSIGQSQQIRLGYNMR
                     IQRAGIDYLNPYVDERDPLNVSYGNPDLDSEKSNSVNLNYTLFTQKFNINASVSHAFV
                     NNSIEQYTFMDTERPNVSVSTYGNIGKRHQTGFSLYMNWSPLPLFRFFMNGGVDYISM
                     ENEERNLSNSGWSGRAFAGVQFSFPKDFWLNMNAGYMLPKIQLQGERSDFLFHGITLN
                     KDFFHKKLTLSVYCKSPLTKTWKMENKTYNNAFTLYETENKVMREFGISVSYRFGSLT
                     DTFRKIKRGIVNDDVKDSGGKDVD"
BASE COUNT         2751 a         2642 c         2785 g         3046 t
ORIGIN      
        1 ctccagatag aaatcgttat aattcatcgg gaagaaagcg tcgatattcc atttattcca
       61 ttcttgacga accatccact tggcgtgaga gtccggcccc gggaatacgg cggcgctcac
      121 tttcttgcct ttgccgtgaa cctcgtcggc gatgcggttt accaatttcg tgatcaagtc
      181 gcaacggaac cgcgcccatt ctgcgcattt ggaaggatcc tctacggatt tgatgtcgat
      241 accggtagcg gccttgaaat cagccacgca tttgtcacag taacaatagt ccgccgtagg
      301 atattcctcg tccatcacca atccgtattt ttcccaaagt ccgcgggcta agatgacatc
      361 cacgtaacgg atataatcca gatggatata atccacctcc gggatatcgg ctaccttgcc
      421 atatagattc agcaagaact ccgccgtacc ttcttggttc gggcacaggc atttgtaata
      481 agggacatac gcctgtacgg aataggccga ctcgcctttc cggtttacgg cataaagggt
      541 ggagtccagt ccatgttgca acatggcggg aatccatgcg tgatattcca tgccattggc
      601 atgggccgct ttggcggcac gctggatttt ctccgtgtca tggccggcgt tgtagcacat
      661 cccgtctaca ccgtgggcat gccatttact aaagtccgcc tgtaaggttt gctcggtggt
      721 attcccacct tcgccttgcc atgcgtagac cttgactgtt ttctcgggag ccttgacgca
      781 agccgtcaga gtgacggccg ccaaggcgat aaagagcttc ttcatatctc gcaagcgcat
      841 aaagtcggta ttaagttacg gtcgccataa gcgttatcca cgcgggctac gttaatccag
      901 aacttgctgt cgtgcaacca ttccagcggg aaggcggcct tcgtgcgggg atacgcgtgt
      961 ttccactcgt cggcggtcac ctcgtattcc ggatgcgggg cgttcttcaa gacgttgtcc
     1021 tccttcgagg ccttgccttc ttccacctcc ttgatctcgc tccagatgca ttccattacc
     1081 tctacgaagc gatccagctc ggccttgctc tcgctctcgg tcggctctac catcaaggtg
     1141 ccgtgtaccg ggaaagatag ggtaggagcg tggtagccga agtccatcag acgcttggcg
     1201 atatcgccct cgtcgatgcc cgaacgctct tttaccgtac ggcattccaa gatcaactca
     1261 tgacctacac ggcctgtcgc tccggtatag acgataccgt acgtatcctt gaacttagcg
     1321 gccaagtaat tggcgttcaa gatggccgtc ttcgtcaccg tctcaagacc ttccgtaccc
     1381 agcaagcgga tgtaagcgta cgtgatcggc aggataccgg cgctaccata aggagccgcg
     1441 gataccgtat tcaagtcgct gccccaaagc accggatgct gcggcaagaa cggaaccaga
     1501 tgctcggcca cgcagatcgg gcctacgccg ggaccaccac ctccgtgagg agaagagaag
     1561 gtcttatgca ggttcaagtg acatacatcg gcgccgatcg tacccggatt tgtcaatcca
     1621 acctgcgcgt tcatgttggc gccatccata taaagctgtc ctccgcaagc gtgaacgatg
     1681 tcgcacatct ccttgatgtc cacctcgaag ataccatgcg tagacggata ggtaatcatg
     1741 ctggcagcca gacgctcctt gttctcctcg gctttcgcac ggaaatcttc cagatcgata
     1801 ttaccattct cgtcgcattt aacggttacg gtcttatacc cgcattggat agcgctggcc
     1861 gggttggttc cgtgggcgga agccggaagc aaaacgatat cacgatggcc ttggccgatg
     1921 ctttcctgat aagcacggat cacacgaaga cccgtgtact cgccagcggc gccggagttc
     1981 ggttgcaacg tacagccctt gaagcccgtg atcgtgcata agtaagaaga caggttctcg
     2041 atcagctccg tatagccttc cacttgctcc tctggagcgt acgggtggat attcatgaat
     2101 tccgcacggc taagcggcaa catcgtagaa gccgggttta gcttcatcgt gcaagatccc
     2161 agcgagatca tggattgggc caaggaaaca tcctttcgtc ccaaacgggt gatgtaacgc
     2221 atcaactcgg tctccgtatg atatttcttg aatacgtctt gctgcaagaa atcggaggta
     2281 cgggcgaatt tagcgtcgaa ataagtctgg gcggggatag actcgtccag catatagtct
     2341 ttacctgcgg cgccggcgaa gatgtataat aatacgccta tgtccgtagg caatgtcgtc
     2401 tcgtctatgc tgacgcccac ttgtccggcc tcgaagtaac gcaagttcac cttgcactcc
     2461 aaggcgatct cacgcagcgc gttcaccgac acgtgtgaag gaagctgtat cttcaaggta
     2521 tcgaaataat ccttgtttaa ttgcgtatat cccagtttct ccaactcctt ggccaagaat
     2581 ccggccgtgg aatgaatccg tccggcgatg ttacgcaacc cctccgctcc atgatatacg
     2641 gcgtagaagc cggccatggt agccaacaac gcctgagccg tacagatatt ggacgtagct
     2701 ttctcacgtt tgatatgttg ctcgcgggtc tgcaaggcca agcgataagc cggatggccg
     2761 taagcgtcct tggagatacc gatgatacgt cccgggatcg tacgtttata atcgtccttc
     2821 gtagcgaaga aagcggcgga aggacccccg tagaacatcg ggataccgaa gcgctggctg
     2881 ctaccgaata cgacatccgc tccccattct cccggaggag tcagcaatac caagctcatc
     2941 aagtcggcgg ctacgcctac cttggctccg gcggcgcccg cacgggccac gaattcctta
     3001 tagtcctcga tcgaaccatc cgcgttcggg aactgtacga tggcggcgaa cacgtccggc
     3061 gtgaactcga atttcttata atcgcccact accacctgga tgccctgcgg gatcatgcgg
     3121 gtgtggatga cggccagcgt agaggcgaac acgttctcgt cgatgaatac cgtattggct
     3181 tccgctttca cctgcgcacg gctgcgtgaa ccatgaaaca tggtaaccgc ctcggctgcc
     3241 gctgtcgcct cgtcgagtag cgagcagttc gccaagggca gtccggtcag ttcgcagata
     3301 acagtctgga agttcagcaa cgcctccaag cgtccttggg atacttccgc ctgatacggc
     3361 gtataggagg tgtaccaaac cgggttctcg aatacgttac gttggatcgg ggccgggcaa
     3421 accgtgtcgt accaacccat accgatataa gaggtgaata cctcgttctt ggaagccagc
     3481 tcggcgatat gctcggcgaa ctcacgttcc gtcatggcct ccgggaggtt caacggctct
     3541 ttcaaacgga tgttggccgg aatggtctga tcgatcaact cgtccaaaga cttcacgcca
     3601 atcgtctcca acatagcggg aatatcttcc gctgagatgc ccacgtggcg gtttacaaac
     3661 ttatttgtgt ccataattct agtattttat aaataaggat tatttaattt ctcatcaatg
     3721 attcgtgtct cggggccatg gccggggtat accacggtct cgtccggcaa cgacagtaat
     3781 ttgtccttga tagcggcaag cagtatatct tggttgcctc cccataaatc ggtacggccg
     3841 atgcttccgg cgaacaagga atccccgacg atcacgaaac cgttcttctt gttatagaaa
     3901 gccacgcctc cgggcgaatg accgggaacg ctcaataccg ccagctcgga tttcccgaac
     3961 tttatgattt ccccgtttac cagatatttc cctaccggga cgcttttcgc cttcatcggc
     4021 aggccgaatg ccttggcttg ctcctcggga gagggaagac cctccacgtc cgctttatgg
     4081 gcttccgggc tcaatccgta ggtatcatgg atgaattcgt taccgaatat gtgatccaga
     4141 tggaggtgcg tacaaaggta acgtttcagt gtcagcccgt tctgggcgat aaagtcgctt
     4201 acttcttttt gttcctcttt gcgtaggcag ccgcaatcga taaggaccgc ctccttggta
     4261 tcatcgtata gcaaatacgt attctcggag aaatagttta cttcgaaaga ttttatcgta
     4321 atcataaggg tacgtacact acttttttag tttcaaaaaa ctcttcttta aaatggtctt
     4381 tcagatccat gctgatcgct tggttccgga aaggcaatat ctcatgtgcc aactcgccac
     4441 ctttcaggca aatcaatccg ttgggcaacg cgttgatctg ttctttcttt atattcttgc
     4501 ggacgatctt taccagatcc gccagaggca tcacggcacg gcttaccacg aaatcgaaaa
     4561 gctgcttttc ctcctcgccc cggcaatggc ggaaggatac gttctccagc ccgatcgcct
     4621 cggccacggc ttgtcccacc ttgatttttt tcccgatgct gtctaccaga tggaaatggg
     4681 tctccgggaa taagatcgcc aaggggatgc cgggaaaacc gcctcccgta cccagatcca
     4741 tcacagagga acccggcttg aaacgcagca tatcggtgat acccagcgag tgaagcacgt
     4801 gatgcggata taggttctcg atatccttcc gtgagatcac gttgatcttg gcgttccaat
     4861 ccgtatatag gtcatatagg gcggcgtatt gctctttttg ccggtcggtg agatcgggga
     4921 aataagatgt gagaattgag aattgagaat tgagaattga aaatttctct gtattttgtt
     4981 ccataggaca tctgtttata ggtttatcta tcattaattt tcaattctca attttcaatt
     5041 aactgactta tcgggctgtc atcccgcagc aaatagcgga tttccttgta agggagatgg
     5101 acgttcgtga cgcctaccac gtatgccgct atctcatatt cgttgaaaga ataggtgata
     5161 cccgtctcgt ctacgaggaa gttgccgttc gggaagatct cgtccacgct aaagaaaccg
     5221 atattttcca gttccttggc gtcggatacg ttgttttgct tggcgatctg atctaccaat
     5281 attcgcgcca gattgtcttg atagttgtcc acgaatatct cctcctcggt gatcggctta
     5341 ccggtcttga ggttcactac atggttattg taggaatgtg cgccatgcgc tccgcccgta
     5401 tagttctcga agcttaccgt atagctgatg atatcgtctt ggttgaaggc gatatcatcc
     5461 gacgacatct catagtaaga gaaccaagag cccaccggtg tctcgtcgga tttcgccacc
     5521 tcagccttgt aatcctcttc cagatcctta taagcggcca gatagtcgtc ggtatatttc
     5581 cgtaccgcct cctcggggga taattgctca taattctcgc cgaaataaga ggagacgaac
     5641 tgtctctgta gattcttaag aacctcttta tccgaatatt tccggggata aacgaacttg
     5701 atctctagat tgcaattggg attatccgga ttatctaaca aatggtaagt cttttccacg
     5761 ctgatagaat caaacgtgat actgttttca gaagccttct tcgttccggt atcgcaaccc
     5821 gtggctaaga tacctatcaa aagaagcgcc agcatgcttt cgcgtaaatg cgttctcatc
     5881 ggactacaga tttaatttat ttgtacgcga atgtacgtta ttaaattgta taatcaaatt
     5941 gcacgatgaa gtttaataag aggacaacca taccttaaat tccgccgcct tatttttagc
     6001 cacgaaaatg ggttcgtcgg tcgggaggct cagatttata cgtaatcggc tatcgaacca
     6061 gatggtgaag ctatctatta cttccttgga aaggataaac tgtcggttta cccggaagaa
     6121 gcaagtcggg tttaatttta tcattaagga gtctagagat ttaccgatgg aatatgattg
     6181 tctctcgcgg gtcaccacgc tactttcgcc gttcgtgtta tagaaataag cgatcgcctc
     6241 ggttttgatc ggtataatcc gatccttgaa tgggacgaga atccgcttta gatattccga
     6301 gctacaaacc aattggtcga tccggctgat atgctgccgt acggtcaccg gattaagtcg
     6361 gttgtattta tctagtgcct ttcgcatgct ctctaacgtg ataggcttca atagataatc
     6421 gacgctgttt acctcgaatg ccttgatcgc atattggtcg tatgcggtag tgaatatgat
     6481 gggaacctct atggtgacgc attcgaaaat attgaaagag tttccgtccg ccaattggat
     6541 atccatgaag atgaggtcgg gcatgggatg actacggagc catgtcacgc tatctactac
     6601 cgtatcgaaa tgatccaaga tctcgatatg cggatctatc tgtagtaata agttcttgat
     6661 gttcttgtag gctgcggcct cgtcttcgat aatgatgatt ttcatgattg tttggattta
     6721 gattaactct ttaaaggtag ggaaacacgg aaaaactcat ccgtatcctc tatccttatt
     6781 ctttttttta cgagtagggc aaagcggtta tctaggtttt tcagcccgat acccactttc
     6841 tccacctcgt ccagcttggg ctgtttccgg tttaggatca ccaaagaagg ttcgtgggtg
     6901 ctgtaaatgg ataatcgcat tgggttgcgg gcgctgatct cattatgctt gatcacgttt
     6961 tctatcaatg gtagcaagga aagaaccggt agctggcagg acatataggc tgggttgatc
     7021 tgtatgtcga acgtcagttt ctcctcatat ttgacggata gcatgaagcg gtaggtttcc
     7081 aaaaaagata gttcgtcctt taacgccact aattctttct tctcgctttg aagtatatat
     7141 cggaatacat tggataggtt ggagagataa gccagtgatt tctgattctg tccttcgact
     7201 atcaaggcat gcaaagagtt caacgcattg aagaaaaaat gagggttgat ctggttgtac
     7261 aaggcatcta tctggctttg cagggattcg tttttcagtt tctcgtagtt tcgctccact
     7321 tcctctttac gtgcggcgag gatataaatc cggctgaacg tgtatattcc aacgaatagc
     7381 gtgaaaaggt tgttgtacca tgcctcctct ggctcgtgga acaagtagaa aagcttcttc
     7441 ccatggaaac ggtggttttc tttcggttcg tttcgctcgt atttctcccg gatattttgg
     7501 tttgtgcttc gtatgacggg tgagaccccg agccatacga ttaaggaaaa taatacggat
     7561 accagcgacg aataggcgaa ttgcttgaga tgcccttttt tctcaggctg ccaacatacg
     7621 ttaatttgta gtagtatccg agtgaacagg atgaaaaaca ggcattggaa gatcaacaat
     7681 aatatactgt cgatctcggg gtcaatccct ctgatccggg atagctcgat acaatccatg
     7741 atctcttcgg aggtcacgaa gaaacccgat aatacggata cccatatcag tatggatggt
     7801 ttctgaagga gataatgtct tattttcatg gcttctcttt ttataggcaa aagtaaagtt
     7861 aaagcttgat ataccctttc ttttcctcct gttttcggat catttaattt tcgccctcaa
     7921 tcctttttct ttcgctttgg acggaaaaac aaaacttttg gcctctccgg gagtcatatt
     7981 tgcgtaataa taaatcacga ttgaatatga aaactgcatt gttttttaag cttttgttcg
     8041 tttgtctagc gtgcgttgcg attcgtcccg tatcggcgca agtactggga gctggtgtct
     8101 ttgagttgaa aggacaggtt gtggactcat tgacaaatga gccggtctcg ttcgcgacct
     8161 tgcgtgtgac gaggggtgag gagattacgg agcctcttgc tttattggct tgcgatattg
     8221 atgggtattt ctctgtctcc ttgcccgagg ccggatctta ttatttccat atgagttcta
     8281 tcgggaaaat acctgctcgg aggaaagtga gcgtttcggc tcaatcgccc gtatggaacg
     8341 taggtaaatt atgtatgaaa gatgatgccc ggacgctggg agaggtgagg gtctcggcgc
     8401 aaagaccttt ggtcaaggtg gatattgata aattggtcta taacttagag gaggatcccg
     8461 aggcgaaagt cagcaataca ttggatatgt tgcggaaggt accgatggta accgtggatg
     8521 gcgatgataa tatccaactg aaaggaaata gtaattttaa gatctacatg aatggacggc
     8581 cctcgggatt gcttagcagt aatccttcga cagtattgaa aagtcttccg gcctccaaca
     8641 tcaaggatat agaggtgata acagatcccg gtgcccgcta cgacgctgag ggagtgagtg
     8701 gaattatcaa tattattatg gtgagacgtg tcttggatgg atatacgggg acggtgagtg
     8761 cggaggttac tacgaacgag gcatacggcg gcgggacatt cgtctcgctg aaagcaggga
     8821 aactgggact tacggcgaat tacaatctgg agtatgaacg tgagcctata gcggatatca
     8881 cttcctttcg caagaactta tcggatgacg ctaaccgtta cctctcccag atcggggagc
     8941 attgggaaag ggagaaaatg caccggggat atttggaggg aactttcgag atcgactcga
     9001 tgaacctgat tagcgtggac gccaatttgt tccgcaagcg tcagaaagag ttctcggatc
     9061 tgagcgtgga gatgcgtgac atgaaccgag acttgattta tgcttacgat cgttttagcc
     9121 agaatcaacc tgtcttcggc tccgtggagg tgaatgccaa ctaccagcat gagacaaggc
     9181 gtaaggggga gttgctgact ttgtcttatc gtttcaccaa tgatccgaat gatgatgaga
     9241 accggatgcg gataacgggt acctcgaatt actctgattt cctgcaatgg gacacgaacc
     9301 gggcgaagac caatgagcat acgggacaat tggattatat aagacccatt gccggggggc
     9361 atgatctgga gaccggagta aaatatatct tgcgccagac cgacagtgag atcacgcaac
     9421 ggctttatga tgagacttcc ggcaattggc atgaaccgtc gggcagcttt gtggatttca
     9481 gccatacgca acatatttac tcggtgtatc tgggtggcac ctttcgttgg aataagctgg
     9541 gaataaaggc tggagtacgt gcggaaggaa cgagcttgga cgtgagctat tcgaatgatc
     9601 tgacgaaaga ctttcattcg aattttgtgg atatcgtacc gaacgttacg ttgtcttact
     9661 cgatcggaca gtcgcaacag atccgtctgg gatataatat gcgtatccag cgtgcgggta
     9721 ttgattattt gaatccttat gtcgacgagc gggatccgct aaatgtttct tatggcaatc
     9781 cagacttgga ttccgagaaa agcaatagtg tgaaccttaa ttatacctta ttcacccaga
     9841 agtttaacat aaatgccagc gtaagccatg catttgtgaa caattctatc gagcaatata
     9901 cttttatgga tacggagcgt ccgaacgtat cggtctctac ctatggtaat atcggcaaac
     9961 ggcaccagac aggcttttcc ctttatatga attggagccc tctcccattg ttccgttttt
    10021 tcatgaatgg tggcgtggat tatatcagta tggaaaacga ggaaagaaac ttgtcgaaca
    10081 gcggttggag cggacgtgct ttcgccggtg tccaattttc gtttccgaaa gatttctggc
    10141 tgaacatgaa cgccggttat atgttaccca agattcaatt gcaaggggaa cgatccgatt
    10201 tcctgtttca cggcattacc ttgaataagg attttttcca taagaagctc acgttatctg
    10261 tctattgcaa gagccctttg acgaagactt ggaagatgga gaacaagact tataacaatg
    10321 cgttcaccct ttatgagacg gagaataagg tgatgcgtga gttcggtata tccgtatctt
    10381 atcgtttcgg gagccttacg gatactttca ggaaaatcaa gcggggcatc gtgaacgatg
    10441 acgtgaagga tagtggggga aaggacgtcg attagtaacg atagtattat gattacgaat
    10501 aggtattcga ggacgatgtg gattttgatg ctgtttctct cacggctttt tcatttaagt
    10561 tttgaattgg gcgtacaatg cctctacgca tgccagtgcg gcatgggcga gaatactatt
    10621 cttatagaca tcagtcgggg tggcggtctt tatggagtct tcaagcccat agcgcaaaga
    10681 tctttgattc ttgccgaagc ggatatttcc ctacggaaaa cctctgcaaa agcagacatt
    10741 cgatcagcca tcttttcatt gtctatgctt tgaaacacac ggcaaagcgt agtttccaag
    10801 ggtaacccat acggaaataa ctctttcgcc tgcaggcgtt tcaagtgacg tttgccaaat
    10861 tgaagcattt taattctacc tacaaagata ggtgcggagg aaggcaagct cacgctcttc
    10921 cttcttggct ttcagccagt gggtgaaggt gtgcgtattg atcccccttc ttttccgggt
    10981 atccctgaat aagaagaatt ttacaataag cagaaaatca ggtcgtgttt tcaaggggtt
    11041 gaaaatcaga gtcgtaaaaa catcgtaatg tttgcgtcga aacacgtaca tgtttttccg
    11101 aaaagtcgta catgtttttg gatattcacg tacgtgtttt tccggaaatg atattgatgt
    11161 aaaataggaa cattaaaaaa agacaataac cttaccttgt gagattctgt cacaagagat
    11221 attc
//
LOCUS       DBMDTB010000116        10981 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_1771_length_10981_cov_12.439063, whole genome shotgun
            sequence.
ACCESSION   DBMDTB010000116 DBMDTB010000000
VERSION     DBMDTB010000116.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 10981)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 10981)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10981
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1771_length_10981_cov_12.439063"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            262..1254
                     /locus_tag="ACZPB4_14545"
     CDS             262..1254
                     /locus_tag="ACZPB4_14545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HIR1099470.1"
                     /translation="MTDRRTFLRNISLLTLGGIASQKVMASNPTRSIPATDAISSATA
                     GKKMGLQTYSLGQELLQDMPNGLNRLAKAGYTDLEIFGYREDTGKFGDYNPKNTTFIA
                     SKDYKKMVDDAGLRISSSHLTPSLREYTKENMPKFDEFWKKATDIHAELGVSCMVQPS
                     LPRIENEDDAKVVSEIFNRAGEITKKAGILWGYHNHSNEFKRVLKAGEKPEQNPNPWA
                     PPKGTYIEELFLKNTDPDKVMFELDVYWAVMGQQDPVEWMENYPNRFKLLHIKDRWII
                     GDSGMMNFPNIFKKAYEIGILGYYVELEGDKKGRTQFEGVEKSAAYLQAAPFVK"
     gene            complement(1428..3737)
                     /locus_tag="ACZPB4_14550"
     CDS             complement(1428..3737)
                     /locus_tag="ACZPB4_14550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008022917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HIR1099471.1"
                     /translation="MNKFFIFILCLCCALTVAQATGEDRLNDSDANVFGHVLDKKTGE
                     HLPFINVLLKGTTIGTTTDNSGHYFLKNLPEGKFTLEYKALGYKTVSKEVSLKKGKTL
                     EINVELEEDQIALDGVVVSANRAETSRRLAPTLVNVLDAKVFTTTNAVNLAQGLNFQP
                     GVRVETNCQNCGFQQVRINGLDGPYTQILIDSRPIFSALSGVYGLEQIPANMIERVEV
                     MRGGGSALFGSSAIAGTINIITKEPLRNSGELSHTLTSIGGTSAFDNNTTLNASLVSE
                     NGKAGLYLFGQNRHRSGFDQDGDGFTELPKLKNQTVGFRSYLKTSTYSKLTFEYHHMN
                     EYRRGGNLLDRPPHEADIAEQLEHSIDGGGLKFDLFSKDYKHKWSVFTSAQNTDRDSY
                     YGTNQDPNAYGKTTDLTVMAGTQYAYSFDKFLFMPSDLTAGLEYSFDHLKDEMIGYNR
                     FTNQKVHIESAFLQNEWKNKRWSFLIGGRLDKHNMMDHVIFSPRANIRFNPTEDINIR
                     ASYSSGFRAPQAFDEDMHISAVGGEVAMIQRAKDLSEEKSQSLSASVDFYHRFKNGIQ
                     LNFLVEGFYSSLSDVFVLEDIGKDEQGNLIKERRNGSGAKVMGLTLEGKSVLTSWLSL
                     QAGATFQRSRYKEAEKWSDDENVPAETKMFRTPDIYGYFTATLTPFKRFTASLSGTYT
                     GSMLVQHLAGYIPLDKAVETPDFFDMNIKLAYEFPLYKELKLEVNGGVQNLFNAYQSD
                     FDQGKNRDSSYIYGPASPRSYFAGVKMSF"
     gene            complement(3784..4134)
                     /locus_tag="ACZPB4_14555"
     CDS             complement(3784..4134)
                     /locus_tag="ACZPB4_14555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009016823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099472.1"
                     /translation="MDRLRKYLRILLPALFIAYLGCIIAFTHVHIVNGVTIVHSHPYH
                     KTDDGRPDHEHGYAEFQLLHQLSVLQITGAAFVAILLAAFYSFIRNLSFAPVYPDYIV
                     PFRGRRTLRAPPIF"
     gene            complement(4219..5772)
                     /gene="ahpF"
                     /locus_tag="ACZPB4_14560"
     CDS             complement(4219..5772)
                     /gene="ahpF"
                     /locus_tag="ACZPB4_14560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008785 - alkyl hydroperoxide reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000302 - response to reactive oxygen
                     species [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HIR1099473.1"
                     /translation="MLESTLKEQLKGIFAGLNANYTFDISISPAHESRQELLDLLGDV
                     ASCSDKISMRVSDGDGLEFILLKDGAKTGIKFRGVPNGHEFTSLLLAILNSDGKGKNF
                     PDESICNRVKALNGPIHLTTYVSLTCTNCPDVVQALNAMTTLNPQIHHEMVDGAINQA
                     EVDALKIQGVPSVFADGKLIHVGRGEFGELLSKLEAQYGINESLTEKTVKRYDVVVVG
                     GGPAGASAAIYSARKGLSVAVVAERIGGQVKETVGIENLISVPETTGTQLADNLRLHM
                     RQYPIDLLEHRRIEKVTIEGNEKVLSTAGGEIFKAPAVIVATGASWRKLNVPGEAEYI
                     GRGVAFCPHCDGPFYKGKHVAVVGGGNSGIEAAIDLAGICSKVTVLEFMDELKADQVL
                     QEKAKSLPNVEIFVSSQTTEVVGNGDKVTGIRTKDRKTGEERVIHLDGIFVQIGLAAN
                     SGVFKEIVETNRPGEIVIDAHCRTNVPGIYAAGDVSTVPFKQIIISMGEGAKAALSAF
                     EDRVRGVLG"
     gene            complement(5792..6358)
                     /gene="ahpC"
                     /locus_tag="ACZPB4_14565"
     CDS             complement(5792..6358)
                     /gene="ahpC"
                     /locus_tag="ACZPB4_14565"
                     /EC_number="1.11.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004291893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0102039 - NADH-dependent peroxiredoxin
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit C"
                     /protein_id="HIR1099474.1"
                     /translation="MEPIINSQLPEFKVQAFQNGNFKTVTNEDVLGKWAIFFFYPADF
                     TFVCPTELVDMAEKYEQFKSMGVEIYSVSTDSHFVHKAWHDASETIRKIQYPMLADPT
                     GALSRAFGVMIEEEGMAYRGTFLVNPEGKIKVAEIHDNNIGRDASELLRKVEAAQFVA
                     SHDGEVCPAKWKKGEATLKPSIDLVGKI"
     gene            complement(6579..7859)
                     /gene="eno"
                     /locus_tag="ACZPB4_14570"
     CDS             complement(6579..7859)
                     /gene="eno"
                     /locus_tag="ACZPB4_14570"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000015 - phosphopyruvate hydratase
                     complex [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004634 - phosphopyruvate hydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HIR1099475.1"
                     /translation="MKIEKITGREILDSRGNPTVEVDILLESGVMGRASVPSGASTGE
                     NEALELRDGDKKRYGGKGVLKAVENINTIIAPALKGMSALDQIGIDHAMLALDGTKTK
                     SKLGANAILGVSLAVAKAAANYLDIPLYRYIGGTNTYVMPVPMMNIINGGSHSDAPIA
                     FQEFMIRPVGAASFKEGLRMGAEVFHALKKVLHDRGLSTAVGDEGGFAPNLEGTEDAL
                     NSIIAAIKAAGYEPGKDVMIGMDCASSEFYKDGIYDYTKFEGEKGVKRTSDEQVDYLE
                     KLINEYPIDSIEDGMSENDWAGWKKLTDRIGNHCQLVGDDLFVTNVEFLSRGIKEGCG
                     NSILIKVNQIGSLTETLNAIEMAHRHGYTTVTSHRSGETEDATIADIAVATNSGQIKT
                     GSLSRSDRMAKYNQLLRIEEELGDRAVYGYKRIN"
     gene            complement(7967..8557)
                     /locus_tag="ACZPB4_14575"
     CDS             complement(7967..8557)
                     /locus_tag="ACZPB4_14575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HIR1099476.1"
                     /translation="MMNSMKTPQEIAEMISKRFYPLPDADLDSLASIIESSKAAKGEL
                     LLDNGQISKYLYYVESGLLRQFYYKNKRDITEHFSCEGNIVICIASTFQREPTRLLIE
                     ALEPTVYHRISFSEFSDLLKTSLAINRLYQKILEWALMLSQEKADSWRFESARKRYLR
                     FQQEYPEAAKRASVNHIASYLLMTPESLSRVRAGVL"
     gene            complement(8744..9478)
                     /gene="pflA"
                     /locus_tag="ACZPB4_14580"
     CDS             complement(8744..9478)
                     /gene="pflA"
                     /locus_tag="ACZPB4_14580"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate-lyase-activating protein"
                     /protein_id="HIR1099477.1"
                     /translation="MIKGKIHSLESFGTVDGPGIRFVVFMQGCPLRCLYCHNPDTWNP
                     KGKVKYQMTPGELLTEVLRYKSFIARGGVTVTGGEPLLQPEFLKEFFRLCQEQGLHTA
                     LDTSGFVCTSKAWEVLDYADLVLLDIKTLNPDLHPLLAGVKQDNTLLFLDELERRGID
                     TWIRHVIVPGYTDNDEWLEALARYVSSYKVVRKVELLPYHTMGTYKYEQLGLDYPLKG
                     VEPLSKERLDNAKAIFSRYKPENNKA"
     gene            complement(9479..>10981)
                     /locus_tag="ACZPB4_14585"
     CDS             complement(9479..>10981)
                     /locus_tag="ACZPB4_14585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase family protein"
                     /protein_id="HIR1099478.1"
                     /translation="VQFVYLAYLAAVKDQDGAAMSIGRTSTFLDIYIEKDIREGKLTE
                     EEAQELVDQLIIKLRIVRFLRTPEYNDLFSGDPVWVTESLGGQGVDGRSLVTRTSYRY
                     LHTLYNLGPAPEPNLTVLWFKNAPENWKRFCAKVSIDTSAIQYENDDLMRPDYGDDYG
                     IACCVSPMKIGKQMQFFGARANLAKCLLYAINGGRDERSGVQVAPMFEPVRGEYLEYD
                     EVMAKYEQMMRWLAKVYVNALKIIHYMHDKYAYEAFEMSLHDGDVERIRATGIAGLSI
                     VADSLAAIRDTKVRVIRDERGLAVDFEREGEYVPFGNNDDRTDSIAVEITEKFMEYLR
                     QHETYRHAKPTQSILTITSNVVYGKKTGTTPDGRIGGTPFAPGANPMNGRDTKGAIAA
                     LASVAKLPFQHAHDGISYTFAVSPATLGKEREVQINNLVSLLDGYFTPDGGQHLNVNV
                     FDKDLLIDAMEHPEKYPQLTIRVSGYAVNFVKLTREQQLDVISRTINHSL"
BASE COUNT         3147 a         2769 c         2097 g         2968 t
ORIGIN      
        1 tgcaaagtta cgatcagaga ctacagcccc acaataccta agaatgggta aaatcacatt
       61 aaaaatccac ggaggtatac caaacaatcc ccttattcag gtaattggat gtatggagta
      121 agttcgtaaa attgagttat gtcaaatttt aaatctattt aaacccaatc gcaagttttt
      181 gagagacatt ttcttaataa acttcaaaaa ggttaactat atttgcgaga aacagatgtt
      241 taattttaat tctttatcac catgacagac agaagaacat ttttgagaaa catttcatta
      301 cttactttag ggggcatagc cagccaaaaa gtaatggctt caaatcccac cagatccata
      361 cccgccacgg atgcgatatc ctcggcaacc gccgggaaaa agatgggatt gcaaacctat
      421 tcgctcggac aggagttact gcaagatatg cctaacggat tgaaccgatt ggcaaaagcg
      481 ggatataccg atctggagat tttcggatat agggaagaca ctggtaaatt cggtgattat
      541 aatcctaaaa atacgacatt catcgcctcc aaggattata agaaaatggt ggatgatgcc
      601 ggtttgagaa tcagtagctc acacctgacc ccttctcttc gtgagtacac gaaagagaat
      661 atgcccaaat tcgacgagtt ctggaaaaag gcaaccgata tccatgccga gctaggtgtt
      721 agttgtatgg tacaaccgag tttaccccgt atcgaaaacg aggatgacgc caaagtagta
      781 tcggagatct tcaaccgtgc cggagagatc acgaagaaag ccggaatcct atggggttac
      841 cataatcata gcaatgagtt caaacgggta ttgaaagccg gcgagaaacc ggaacagaac
      901 ccgaatccgt gggcacctcc taaaggtact tatatcgagg agttattcct aaaaaatacc
      961 gatccggata aggttatgtt cgagttggat gtatattggg ccgttatggg gcagcaagat
     1021 cccgtggaat ggatggagaa ttatccgaat cgttttaagt tattgcacat caaggatcgt
     1081 tggatcatcg gtgattccgg tatgatgaat ttcccgaata tattcaaaaa agcgtacgag
     1141 atcggtatcc tcggctacta cgtggaactg gaaggtgaca aaaaaggccg tacccagttc
     1201 gagggcgtag agaagagcgc cgcctatttg caagccgctc cgttcgttaa ataaaacatc
     1261 ccgatttatc ccataaaaaa gacagtgttt ccgtagagcg atcatatgct tgggaacact
     1321 gtctttttgt ttattttgcc ttcaaaaaaa cacgtacgtc ttttttcgga aacacgtaca
     1381 tgtttttcac gaaacacgta catgtttttt caaagggcat tacatgatta aaaactcatc
     1441 tttacaccgg caaaataact tctcggacta gccgggccat agatatagga ggaatcccgg
     1501 ttcttacctt ggtcaaagtc ggattggtaa gcgttaaaca gattctgcac gcctccattt
     1561 acttctagtt tcagctcttt gtaaagcggg aactcatacg caagcttgat attcatatca
     1621 aagaaatccg gagtctccac cgccttatcc aaaggtatat atcccgccaa atgctgcacc
     1681 aacatacttc ccgtataggt tcccgacagg gaagccgtga aacgtttgaa aggcgtaagg
     1741 gtagccgtaa aataaccata gatatccggc gtacggaaca tctttgtctc ggctggcaca
     1801 ttctcgtcat cgctccattt ctcggcctct ttataacggc ttcgctggaa agtagcgccc
     1861 gcttgcaaag atagccatga agttaacacc gactttcctt ccaaggttaa tcccatcact
     1921 ttcgccccgg aaccgttacg acgttcctta atcagattgc cttgctcatc tttcccaata
     1981 tcttccaaga caaacacatc acttaagctg gagtaaaaac cttccaccaa gaagttcaac
     2041 tggataccat tcttaaaacg atggtaaaaa tcgaccgaag cactcaagct ctgcgatttc
     2101 tcctcggata aatctttcgc acgctggatc atagcgacct ctccgccgac cgccgagata
     2161 tgcatatcct catcgaacgc ttgcggggca cggaaaccac tggaataact agcccggata
     2221 ttgatatctt ccgtcgggtt aaaacggata ttcgcacgag ggctgaatat tacatgatcc
     2281 atcatattat gtttatccaa acgaccgcca atcaagaagc tccatcgctt atttttccac
     2341 tcattctgca aaaacgcact ctcgatatgc accttctgat tcgtaaagcg attatacccg
     2401 atcatctcgt ctttcaaatg atcgaaacta tactccaaac cggcagtcaa atccgatggc
     2461 ataaacaaga atttatcaaa actataagca tattgcgtac cggccataac cgtcaggtcc
     2521 gtagtcttgc cgtaagcgtt cggatcttgg ttcgtcccgt aataactatc ccggtctgta
     2581 ttctgggcag aagtgaaaac actccattta tgtttgtaat ccttggagaa aagatcgaat
     2641 ttcagacctc ctccatcaat cgaatgctcc aactgttcgg cgatatccgc ttcatgaggc
     2701 ggacgatcca acagatttcc tcccctgcgg tattcattca tatgatgata ctcgaatgtc
     2761 aatttactat aagtactcgt tttcaggtac gaacggaaac caaccgtttg attcttcaat
     2821 ttaggcaact ccgtaaaacc atctccatcc tgatcaaaac cggaacgatg acggttctgg
     2881 ccaaaaagat ataagcccgc tttcccattt tccgatacca aagaggcatt tagggtcgta
     2941 ttattatcga aagcagatgt cccgccaatc gaggttaacg tatgcgacaa ttccccggaa
     3001 tttctcaagg gctccttcgt gatgatatta attgtcccgg cgatagcgga cgagccgaac
     3061 agtgccgatc cccctcctcg catcacctct acccgctcga tcatattcgc cggtatttgc
     3121 tcaagcccat atacgccgga taaagcactg aatatgggac gtgaatcaat cagtatttgg
     3181 gtataaggtc cgtctaatcc attgatccgg acttgctgga aaccgcaatt ctggcaattc
     3241 gtctccaccc gtacacccgg ttggaaattt agtccctgtg ccaaattcac cgcattggtc
     3301 gtagtaaaaa ccttcgcatc caatacattc actaatgtgg gagccaaccg gcgggaagtt
     3361 tccgcacgat tcgcagatac caccacgcca tccaaggcga tctggtcttc ttccagttct
     3421 acattaatct ctaaggtttt tcctttcttt aggctcactt ctttagagac agtcttatac
     3481 ccgagcgctt tatattccag cgtaaattta ccttccggca gattcttcag gaaataatgt
     3541 cccgagttat cggtggtcgt accgatcgtg gtacctttta acaatacgtt gataaaggga
     3601 agatgttccc ctgttttctt atccaagaca tgtccgaaaa catttgcgtc tgagtcgttt
     3661 agacggtcct ctcccgtggc ctgagctacc gttagggcac agcacaggca tagtataaag
     3721 atgaaaaatt tattcatttt aatttattct gataagtaat acaatgttat taatctcaca
     3781 atatcagaat atgggaggag cccgaagcgt acgtcttccc cggaagggaa cgatatagtc
     3841 cggatagacc ggagcgaaag ataagttacg gataaaggaa taaaaagccg ccagcagaat
     3901 agcgacgaaa gccgcacctg ttatctgcaa gacagataac tgatgaagca actgaaactc
     3961 ggcgtagcca tgttcatggt ccggacgacc atcgtccgtt ttatgatacg ggtgagaatg
     4021 gacgattgtt accccgttga caatatgaac gtgggtaaac gcaataatac atcccaaata
     4081 ggctatgaac agcgcaggga gtaatatcct cagatatttt cttaatctat ccatctcttt
     4141 tctctcgatc gcaaatatag taatataacc gataaaagag atacgctgtt caaaaattac
     4201 ctatttgtag gtatttcatc aaccgagtac accacgtacc cgatcttcaa aggccgaaag
     4261 ggccgctttg gcgccttctc ccatagaaat aatgatttgc ttaaagggta cggtggaaac
     4321 gtcgcccgct gcataaatac ccgggacatt cgtccggcaa tgtgcgtcaa tcacgatctc
     4381 accgggacga tttgtttcga caatctcctt aaagacacca ctattagcgg ctaagccgat
     4441 ttgaacaaaa ataccgtcta aatgaataac acgctcttcc cctgtcttac gatcctttgt
     4501 acggataccg gttaccttgt cgccatttcc aaccacctcg gttgtttgtg aactaacaaa
     4561 gatctcgaca ttcggcaaac tcttcgcttt ctcttgcaag acttgatccg cttttaactc
     4621 atccataaac tccaaaacgg ttactttcga acagatcccc gccaaatcaa tagccgcctc
     4681 gataccggaa tttccaccgc caaccacggc aacatgtttt cccttataaa acggaccgtc
     4741 gcaatgagga caaaaagcca ctccacgccc tatatactct gcctcacccg gtacattcaa
     4801 tttacgccag ctagcgcccg tagcgacaat aaccgccgga gccttgaata tctcacctcc
     4861 agccgtagat aaaaccttct cgtttccttc tatcgttacc ttctctatac gacgatgctc
     4921 cagcaggtca atcggatatt gccgcatatg caagcgcaga ttgtcagcca actgggtacc
     4981 tgttgtctcc ggaactgaaa tcagattctc aattcctacc gtctccttca cctgcccgcc
     5041 gatacgctcc gccacgacag cgacactcag cccctttcgt gcggaataaa tagcggcaga
     5101 agcaccagcc ggacccccac cgaccacaac cacgtcatat cgttttaccg tcttctccgt
     5161 caggctctca ttgattccat actgagcttc cagcttcgat aacaattcac cgaattcccc
     5221 acgtcctaca tggatcagtt ttccatccgc aaagacagag gggacgcctt gtatcttcaa
     5281 ggcatcaact tccgcctgat tgatagcccc atctaccatc tcatgatgga tctgaggatt
     5341 taaagtcgtc atagcgttta atgcctgtac cacatccggg caattcgtac aagtcaaaga
     5401 gacataggtc gtcagatgta tcgggccatt caaggcttta acacgattac aaatgctctc
     5461 gtccggaaaa ttcttgcctt tcccatctga attcaagatc gccaacagca aggaagtaaa
     5521 ctcgtgtcca ttaggtactc cacgaaactt aatccccgtt ttcgctccat cctttaataa
     5581 aatgaattcc aatccatccc catcagatac tcgcatagat attttatccg aacaagaggc
     5641 aacatcacct aataaatcca acaactcttg tctactttca tgcgcaggag agatcgatat
     5701 atcaaaggta taattcgcat ttaaccctgc gaatatacct tttaattgtt cttttaatgt
     5761 tgattctaac acgatctata ctcttaatta tttagatttt ccctaccaag tcaatgctag
     5821 gtttcaaggt agcctcccct ttcttccatt tagcgggaca aacctcacca tcatgtgaag
     5881 cgacaaactg agcggcttca actttacgaa gtaactcgga agcgtcacga ccgatattgt
     5941 tatcatgaat ctcggccact ttgatctttc cttccggatt taccaagaaa gtgccacggt
     6001 atgccatacc ctcttcctca atcatcacac caaacgcacg actcagtgct ccagtgggat
     6061 ccgccaacat cggatattgg atcttacgga tagtctcgga agcgtcatgc caagctttat
     6121 gtacaaaatg agagtctgta cttacagagt aaatttctac tcccattgat ttaaactgct
     6181 catacttctc agccatatcg accaactctg ttggacaaac aaatgtaaaa tcggccgggt
     6241 agaagaaaaa gatagcccac ttacccaaaa cgtcctcgtt ggttacagtc ttgaaattac
     6301 cattttgaaa agcttgtact ttaaactccg gaagttgaga attaataatc ggttccatac
     6361 ttgttcctat ttttaaatga atactatttg tttttatttc cgatacaaaa atataacata
     6421 tttcttcatt aaaacaattt ttctaatcga tatattttat gaggttatag ataacacttt
     6481 atcaatcaat aaaaagggcc tatcctcacg gataagccct tcaatatctt gggttttgga
     6541 ttactacata attagcgatt ataatttact ttatatactt aattgattct tttgtatccg
     6601 tatacggcac ggtctcccaa ttcctcctcg atacgaagca gctggttata tttagccata
     6661 cggtccgaac gacttaatga tcccgtcttg atctgtccgc tattggtagc gacagcgata
     6721 tcggcgatcg tagcgtcttc cgtctcaccg gaacggtgtg aagtaacggt cgtgtatcca
     6781 tgacggtgag ccatctcgat agcgttcagt gtctccgtca aggaaccgat ctgatttacc
     6841 ttgatcaaga ttgagttacc gcaaccttct ttaatacccc ttgaaaggaa ctctacattt
     6901 gtcacgaaca aatcatctcc gactaattgg caatggttac caatacgatc tgtcagtttc
     6961 ttccaaccag cccaatcatt ctcactcata ccatcctcaa tggaatcgat cgggtattcg
     7021 ttgatcagct tttccagata atccacttgt tcgtcggaag tacgtttcac tcctttttct
     7081 ccttcaaact tcgtgtaatc gtagattcca tccttataaa actcagaaga agcgcaatcc
     7141 ataccgatca tcacatcctt gcccggttca taaccagccg ccttgatagc agcgataatt
     7201 gagttcaagg catcttccgt accttccaaa ttcggggcga aaccaccctc atcaccaaca
     7261 gcggtactta acccacgatc gtgcaatacc tttttcaacg catggaatac ctcagcgccc
     7321 atacgtaagc cttccttgaa agaagcggca cctaccggac gaatcataaa ctcttggaaa
     7381 gcgatcggag cgtcgctatg cgaaccgcca ttgattatat tcatcatcgg aacaggcatc
     7441 acgtaggtat tcgttccacc aatatatcta tataaaggaa tatccaaata atttgcggca
     7501 gctttcgcta cagctaaaga aacgccaagg atagcgttcg cacctagttt cgatttagtt
     7561 ttcgtaccgt ccaaagccaa catcgcatga tcgataccta tctgatccaa ggcagacatc
     7621 cccttcaatg ccggagcgat aatcgtattg atattctcaa ccgctttcaa tacgccttta
     7681 ccaccataac gcttcttatc gccatcacgc aactccaaag cctcgttctc gccggtggac
     7741 gcaccggaag gcacagacgc acggcccata acgccggact ctagtaaaat atcaacctct
     7801 actgtcgggt tacctcttga atctaggatc tcacgtcctg taatcttttc tattttcatt
     7861 gcttctacgt tttttaaact gacgcaaata tagatggatt acttgaaccg tgaaatcacc
     7921 acaaattgct attttcacct caataatacc tgaatgtagg tagagactac aacactcccg
     7981 cccgcacccg gctcaaagat tcgggtgtca tcaataaata cgaggcgata tgattgacag
     8041 aagcacgttt cgctgcttcc ggatattcct gttgaaaacg cagataacgt tttcttgccg
     8101 actcaaaacg ccaagagtcc gctttctctt gcgaaagcat caaagcccac tccagtattt
     8161 tctggtacaa tctattaata gctaaagatg ttttcaataa atcgctaaat tccgaaaaag
     8221 agatccggtg ataaaccgtc ggttccaatg cctcgattaa taaacgcgtc ggttctcttt
     8281 ggaatgtgct ggctatacaa ataacgatat ttccctcaca ggagaaatgc tcggtaatat
     8341 cacgtttatt cttatagtaa aactggcgta ataatcccga ttccacataa tataaatatt
     8401 tagatatttg tccgttatcc aacaataatt ctcctttcgc agccttactt gattctatga
     8461 tcgaggccag agaatccaaa tccgcatcgg gtaatggata aaaacgtttg gatatcattt
     8521 cggctatttc ttgtggtgtc ttcatactat tcatcatttt ctgatctata tcatttttta
     8581 tctccttaca aaaatagata tttgttgcat ataacaaaac aaacacatat taaatagtca
     8641 aggttagtct aggcaaaaaa ttattactat cgtttaaaag ctaatcggat tagattgttt
     8701 tccctgatta gctgttgcat aatcgcaagg cttgatcgag agatcaggcc ttgttatttt
     8761 ctggtttgta gcgagagaat atcgctttcg cattatctaa acgttctttt gataagggtt
     8821 ccaccccctt taacggataa tcgagaccta attgctcata tttataggtt cccatcgtat
     8881 gataaggcaa taattccact ttgcgaacca ctttatatga actgacatac cgagctaacg
     8941 cctccagcca ctcgtcatta tccgtatatc cggggacaat aacatggcga atccaagtat
     9001 ctatgccacg tctctccaat tcatccaaga acagaagcgt attatcctgc ttgacacccg
     9061 ccagtaacgg atgtaaatcc gggtttaagg ttttgatgtc caataacact aagtccgcat
     9121 aatccaagac ttcccaagct tttgaggtac atacgaaacc agatgtgtcc aaagctgtgt
     9181 gaagaccttg ctcttggcac aaacggaaaa actctttcag aaactcaggt tgcaataaag
     9241 gttccccacc ggtaacagtc acccccccac gggcgataaa actcttatac cgtaagactt
     9301 ccgtcaatag ctcgccggga gtcatctgat atttcacctt ccctttcggg ttccaagtat
     9361 ccgggttatg gcaatacagg caacgcaacg ggcagccctg cataaaaacg acaaagcgaa
     9421 ttccgggacc atctacggtc ccgaaactct ctaatgaatg tatcttacct tttatcactt
     9481 acagtgaatg gttaatggtt cttgaaataa catccaactg ttgttcacga gtcagtttca
     9541 cgaagtttac cgcatatccg gatacacgga tcgtaagttg cggatatttc tcaggatgtt
     9601 ccatagcgtc gatcaacaaa tccttatcaa atacgttaac attcagatgc tgacctccat
     9661 ccggagtaaa atagccatcc aataagctaa ccagattatt gatctgcact tcacgctcct
     9721 ttcccaacgt agccggagaa acagcgaaag tataagagat accgtcgtgc gcatgctgga
     9781 atggaagctt cgctaccgaa gctagcgcag cgatagcacc tttcgtatca cgaccgttca
     9841 tagggttcgc gcccggagcg aaaggagttc caccgatacg gccatccggt gtcgtaccag
     9901 tcttcttacc atataccaca ttagaggtga tcgtaaggat ggactgcgta ggtttcgcat
     9961 ggcgataggt ctcgtgctga cgcaaatatt ccatgaactt ctcggtgatc tctacagcga
    10021 tactatccgt acgatcgtcg ttattaccga aaggaacata ttctccctca cgttcgaaat
    10081 caaccgccaa gccacgctcg tcacggatca cacgtacttt cgtatcacgg atagcagcca
    10141 acgaatcggc aacgatagaa agaccggcga tacctgtcgc acggatacgc tctacatctc
    10201 catcgtgaag cgacatctcg aatgcctcat atgcgtattt atcatgcata taatggatta
    10261 tcttcaaggc gttcacatac actttcgcca accagcgcat catttgctca tacttagcca
    10321 tcacctcatc gtattccaga tactcgccgc gaaccggctc gaacatcggg gctacctgta
    10381 cgccgctgcg ctcatcccgt cctccgttga tcgcatataa taaacatttc gccaaattcg
    10441 cacgggctcc gaagaactgc atctgcttac cgatcttcat aggagaaacg caacaagcga
    10501 taccataatc atctccataa tccggacgca tcaaatcgtc gttctcatat tggatagccg
    10561 atgtatcgat agagaccttg gcacagaagc gtttccagtt ctcgggagcg ttcttaaacc
    10621 acagaactgt caaattgggt tctggtgccg gacctagatt atataatgta tggagataac
    10681 gataggaagt tcttgttacc aaagaacggc catccactcc ttggccgccc aaggactctg
    10741 ttacccaaac cggatcaccg gagaacaaat cattgtattc cggcgtacgt aagaaacgaa
    10801 cgatacgcaa cttgatgatc agctggtcta ccaattcttg cgcctcctct tcggtcaact
    10861 taccctcacg gatgtctttc tcgatataaa tatccaaaaa cgtagaagta cgtccgatag
    10921 acatcgccgc gccatcttgg tcttttaccg ccgccagata agctaagtac acaaactgaa
    10981 c
//
LOCUS       DBMDTB010000117        10942 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_1782_length_10942_cov_11.238631, whole genome shotgun
            sequence.
ACCESSION   DBMDTB010000117 DBMDTB010000000
VERSION     DBMDTB010000117.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 10942)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 10942)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10942
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1782_length_10942_cov_11.238631"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..284)
                     /locus_tag="ACZPB4_14590"
     CDS             complement(<1..284)
                     /locus_tag="ACZPB4_14590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 30 protein"
                     /protein_id="HIR1099479.1"
                     /translation="MKIPVFILSISLYFSSCSFTPRAEWVTTTENTPWAEQPDLISAL
                     ADTIPNIDITILTEKHQQQIDGFGACFNELGWLSLSKLEPSVREEIMEEL"
     gene            complement(419..1774)
                     /gene="hisS"
                     /locus_tag="ACZPB4_14595"
     CDS             complement(419..1774)
                     /gene="hisS"
                     /locus_tag="ACZPB4_14595"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008151426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HIR1099480.1"
                     /translation="MQKPSIPKGTRDFSPEEMAKRNYIFNTIREVFHLYGFQQIETPA
                     MENLSTLMGKYGEEGDKLLFKILNSGDCFAGISDEELMEKNPLRFAAKACEKGLRYDL
                     TVPFARYVVQHRNEISFPFKRYQIQPVWRADRPQKGRYREFYQCDGDVVGSDSLINEV
                     ELIQIMDEVFHRFGIRVCIKMNNRKILSGIAEIIGEADKIVDITVAIDKLDKIGLDNV
                     NEELRSKGLPEEAIERLQPIIMLQGSNQEKIATLKEVLSASETGLKGVAELDFILERI
                     SHTPIRAELELDLTLARGLNYYTGAIFEVKALDVQIGSITGGGRYDNLTGVFGMEGVS
                     GVGFSFGADRIFDVLNQLDLYPEGSLKTTQLLFVNFGQKEEIHLLPLIAKVRKAGIRT
                     ELYPEPAKMKKQMGYADAKKIPFVAIVGENEMAENKINLKNMLTGEQTLVTIEELIER
                     F"
     gene            complement(1950..2636)
                     /locus_tag="ACZPB4_14600"
     CDS             complement(1950..2636)
                     /locus_tag="ACZPB4_14600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008151428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HIR1099481.1"
                     /translation="MSMYWIIFIGFALLSWLVSSRLQGKFEKYSKIPMPNGMTGKDVA
                     EKMLHDNGIYDVKVISTPGHLTDHYNPANQTVNLSESVYYSNSIAAAAVAAHECGHAV
                     QHATAYAPLRMRSALVPVVSFASNIMTWVLLGGMLLLHTFPQLLLFGIILFATTTLFS
                     FITLPVEINASQRALAWLSNAGITNAYTHDKAEDALRSAAYTYVVAALGSLATLLYYI
                     MIFLGGRSRD"
     gene            complement(2757..4028)
                     /locus_tag="ACZPB4_14605"
     CDS             complement(2757..4028)
                     /locus_tag="ACZPB4_14605"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004301093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HIR1099482.1"
                     /translation="MKVDVLLGLQWGDEGKGKVVDVLTPNYDVVTRFQGGPNAGHTLE
                     FNGEKYVLRSIPSGIFQGGKINVIGNGVVLDPLLFKQEAESLAASGHDITKQLYISKK
                     AHLILPTHRILDAAYEAAKGSGKIGTTGKGIGPTYTDKISRNGVRVGDLLHNFEEKYA
                     AAKAKHEAILRSLNYEYDITEMEAQWMEALNYLKQFKLIDSEHVINNYLKEGKSVLAE
                     GAQGTMLDIDFGSYPFVTSSNTICAGCCTGLGVSPRNIGEVYGIFKAYCTRVGSGPFP
                     TELFDEVGDKIGQLGHEFGAVTGRKRRCGWIDLVALKYAVMINGVSQLIMMKSDVLDT
                     FDTIKACVAYKMNGVETNEFPYEIDDTIEPVYVELPGWKTDMTKMQSEDEFPEEFNAY
                     LSFLEEELGVPVKIVSVGPDREQTIVRYTEE"
     gene            complement(4062..4523)
                     /locus_tag="ACZPB4_14610"
     CDS             complement(4062..4523)
                     /locus_tag="ACZPB4_14610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HIR1099483.1"
                     /translation="MEAKVYTEIRALFTEYLTEKKLRKTEERYAIFKEICAFPGHFDV
                     CMLSDRLEQDNFHVSKATLYNTLDVLVDAGLVVRHQITVQSVQYELRIYADTHLHLVC
                     TRCGTMRELRNSALKADMRNLKVSRFTPEYYCLYIYGLCSKCKFKQQRSVK"
     gene            complement(4579..5274)
                     /locus_tag="ACZPB4_14615"
     CDS             complement(4579..5274)
                     /locus_tag="ACZPB4_14615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006307 - DNA alkylation repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HIR1099484.1"
                     /translation="MESLQDEIREIRKELRLAMNGVISTSMREKGIVYKLNFGVPYPE
                     IKGIARKHKPNGELAAALWKEDIREFKILATFLQPAETLPLDEAKRWVKEIPYLEIAE
                     HCCRNLFVHLPYMEDFTSDLVADKKNEFARTVAFLTWAENFKRGGSLSSVVLGSFLAE
                     TLSSLAETKDFKSTLKEKQASIQAMKFYGRQSEGNAERILDGFKEFQEAAGNTPELQE
                     IYNELKFEFEYYR"
     gene            complement(5278..7338)
                     /locus_tag="ACZPB4_14620"
     CDS             complement(5278..7338)
                     /locus_tag="ACZPB4_14620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008777937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidyl-peptidase 3 family protein"
                     /protein_id="HIR1099485.1"
                     /translation="MKKIMLSLMTAMVMTACTGQQSDTASQNSDKEFNYVVDQFADLE
                     ILRYKVPGFESLSLQQKQLLYHLSEAALMGRDIFFDQNGRYNLAIRRTLEAIYTNYKG
                     DREDPQFKALETYLKRVWFSSGIHHHYALDKFAPGFSPEFLMDCIHQIDAKKLPLREN
                     QNVDQFMIEIAPVIFDPGVMPKRSVQSGDGDLIKASSNNYYGGGISQKEVEDFYAQMK
                     MGKDTISPISYGLNSRLVKENGTVVEKVWKVGGLYSAAIEKIVDQLRQALPFAENDTQ
                     KAIIGKLIEYYQTGDLKTFDAYSILWVEDTASEVDFVNGFIETYGDPLGMKASWESTV
                     NFTNKEATKRTKIISDNAQWFEDHSPVDKRFKKEKVKGVSAKVITVSMLGGDCYPATP
                     IGINLPNADWIRRDHGSKSVTIENITEAYDKASQGNGFSEEFVWSDVERNGMRQYGFL
                     TDNLHTDLHECLGHGSGKLLENTDPDALKAYSSTLEETRADLFGLYYLADPKLVELGL
                     LPDGEAYKSEYYKYIMNGLMTQLVRIELGKNVEEAHMRNRQLIAKWAYEKGKEANVIE
                     LKKRDGKTYVVVNDYPRLRELFGTLLAEIQRIKSEGDYAAGKNLVEGYGVKVDPELHA
                     EVLERYAKLNLAPYKGFVNPVMKEVKNSNGEVTDIVLDYTEGYTDQMLRYGRDYSFLP
                     TYNN"
     gene            7508..8584
                     /gene="mnmA"
                     /locus_tag="ACZPB4_14625"
     CDS             7508..8584
                     /gene="mnmA"
                     /locus_tag="ACZPB4_14625"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005650427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HIR1099486.1"
                     /translation="MEIAALVSGGVDSSVVVHQLKEAGYDPTIFYIRIGMEDKDGYID
                     CPAEEDIEITSYIARKYGCRFEIVSLHDEYWDRVVSYTIESVKRGLTPNPDMMCNKYI
                     KFGCFEEKWGKDFDKIATGHYATTTEIDGKIWLSTAKDPVKDQTDFLGQITRLQIQKL
                     MFPIGHLMKSEVRAIAEAQKLPSAKRKDSQGICFLGKINYNDFIERYLGKRPGKIVEL
                     ETGKVLGKHNGYWFHTIGQRKGLGLSGGPWFVIQKDIKRNIIYVSNGYDPETQYGKVI
                     NMQGFDFITEDPWGEFEGEKEITFKIRHTPEFTHGYIRRIGDLYRVESDEKIQGIAPG
                     QYSVIYDKDHHLCLGSGMIIDETK"
     gene            complement(8664..9605)
                     /locus_tag="ACZPB4_14630"
     CDS             complement(8664..9605)
                     /locus_tag="ACZPB4_14630"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007654670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004749 - ribose phosphate diphosphokinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0006015 - 5-phosphoribose 1-diphosphate
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009156 - ribonucleoside monophosphate
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009165 - nucleotide biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate pyrophosphokinase"
                     /protein_id="HIR1099487.1"
                     /translation="MSAQTPFLVFSGTNSRYLAEKICNSLGCPLGQMNIQHFADGEFS
                     VSYEESIRGRDVFLVQSTFPNSDNLMELLLMIDAAKRASAHSIIAVVPYFGWARQDRK
                     DKPRVSIGAKLIADMLSTAGINRLITMDLHADQIQGFFNVPVDHLYASSVFLDYIKTS
                     LPLDNLCIATPDVGGTKRASSYSKYLGLPMVICHKSRLRANEVAEMRIIGDVTGLDVL
                     LVDDMVDTAGTITKAANLMLENGAKSVRAIASHAVMSDPASTRVDQSALAEMIFTDSI
                     PYAKKCEKVKVLSVADMFAEAIRRVCSGESISSLYAI"
     gene            10304..>10942
                     /locus_tag="ACZPB4_14635"
     CDS             10304..>10942
                     /locus_tag="ACZPB4_14635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008766888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HIR1099488.1"
                     /translation="MEFLLDFILHIDQHMIEIVQEYHTWAYAILFLIIFCETGLVATP
                     FLPGDSLLFVAGAITALPGMPLEINLLALILFAAAVLGDSCNYMIGHFFGRKLFNNPN
                     SKIFKKSHLDKTHEFYKKYGGKTIIIARFVPIVRTFAPFVAGMGKMHYYYFMIYNLIG
                     GAFWVLLFCYAGYFFGDLPFVQQNLKLLIIAIIFISILPAVIEVVRAKLKARK"
BASE COUNT         3180 a         2730 c         2055 g         2977 t
ORIGIN      
        1 aaaagctctt ccatgatttc ctcacgtaca cttggctcca gcttactcaa ggaaagccaa
       61 cctaattcat taaaacaggc tccgaaacca tcaatttgtt gttgatgctt ttctgttaga
      121 attgttatat caatattagg tatcgtatcc gcaagggcgg agatcagatc gggttgctca
      181 gcccaagggg tattctcggt tgtcgttacc cactcggcac ggggggtgaa agagcaggaa
      241 gaaaagtata aagatattga gagtataaaa acaggtattt tcatggtcgt ttcattaatt
      301 tataagttta gaaccatttg aacacggact acacggatga cacggaacac acggtattag
      361 tatttatccg tgtgttccgt gtcatccgtg tagtccgtgt tccataatcc actattctct
      421 aaaagcgttc tatcaactcc tcgatagtca caagggtttg ctcacccgtg agcatattct
      481 ttaagttgat tttattctcg gccatctcat tctctccgac tatcgcgacg aacgggattt
      541 tcttagcgtc cgcatatccc atttgctttt tcatcttagc aggctccgga tatagctccg
      601 tacgaatacc ggccttgcga accttagcga tcagcggcaa taaatgaatc tcctctttct
      661 gtccgaagtt cacgaataga agctgtgtag tcttcaaaga cccttccgga tataaatcca
      721 attggttcaa tacatcaaag atacgatcag cgccgaaaga gaaaccgaca ccagatacgc
      781 cttccatgcc aaatacccct gtcaggttgt catagcgacc accacctgtg atactaccga
      841 tctgtacgtc caaggctttc acctcgaaaa tcgcacctgt ataatagttt aagccacgag
      901 ccaatgtcag atcaagctct aattccgcac ggattggcgt atgagagatg cgctccaaga
      961 taaaatccaa ttcggctaca cctttcaaac cagtctcaga cgcagataat acctctttca
     1021 aggtagcgat cttttcttga tttgaaccct gcagcataat gatcggctgc aaacgctcga
     1081 tcgcctcctc gggtaaaccc ttggaacgaa gctcttcatt cacgttgtcc aagccaatct
     1141 tatccagctt gtcgatagct accgtaatgt ctacgatctt atccgcctcg cctatgattt
     1201 cggcaatacc ggaaaggatc ttacgattgt tcatcttgat acacacacga atgccaaagc
     1261 gatggaacac ctcgtccata atctggatca gctccacctc attgatcaag gaatcagacc
     1321 ccacaacgtc gccatcacat tggtagaact cccggtaacg tcccttttgc ggacgatctg
     1381 cacgccaaac cggttggatc tggtaacgtt tgaacggaaa actgatctca ttacgatgtt
     1441 gtaccacgta acgagcgaac ggaacggtca aatcataacg caagcctttc tcacaagcct
     1501 tagcagcaaa tctcaacggg ttcttttcca ttaactcctc atctgagatg cccgcgaaac
     1561 aatctccgga attcaatatc ttgaaaagga gcttatcccc ttcctcacca tatttcccca
     1621 tcaatgtaga aaggttttcc atggcaggag tctctatttg ctggaagcca tacaagtgaa
     1681 atacttcacg gatcgtgttg aatatataat tacgtttcgc catttcctcc ggcgaaaaat
     1741 cccgggtacc tttgggtatg gaaggttttt gcatgatctt atgttttaaa tgattattct
     1801 gtccgcaaag gtaatgtttt tgctcgaaat aaataagaaa ataacaatgc ccactgtaag
     1861 gagcttacaa tcgcagttat aagcatctta caatgggcat tctaacatct ttataatggg
     1921 cattcgagga aagcctcctc cgagacttat caatccctgc ttcttccccc caagaatatc
     1981 attatataat ataataatgt agcaagcgaa cctaacgctg cgaccacgta cgtataagcg
     2041 gcggaacgta aagcgtcctc tgccttatca tgcgtataag catttgttat accggcattg
     2101 ctcaaccacg ctaaagcacg ttggctggca ttgatctcga ccggaagcgt gataaagcta
     2161 aatagcgtag tcgtagcgaa caagattata ccgaataaca atagctgagg aaacgtatgc
     2221 aataataaca taccacccag caacacccat gtcatgatat tagaggcgaa actaacaacc
     2281 ggaaccaaag ccgaacgcat ccgtaacgga gcgtaagcgg tagcatgctg cacggcgtga
     2341 ccgcactcat gggcggcaac cgcagcggcg gcgatactat tgctataata aaccgactca
     2401 ctcaagttca ccgtctggtt agcgggattg taatggtccg tcagatgtcc gggtgtagaa
     2461 atcaccttta catcatagat accattgtca tgcaacatct tctcagcgac atcttttcct
     2521 gtcatgccat tcggcatagg gattttcgaa tacttctcaa acttgccctg aaggcgggat
     2581 gacaccagcc aactcaatag cgcaaatcca ataaatataa tccaatacat actcataaat
     2641 ttctatctta tttagtttta taaaacaacg acaaaaagtt tgccaaagac aaaaatggca
     2701 ggagacaccc cttgaggaat gtggtcttct gccattttgt acgatttata acgagtttat
     2761 tcttctgtat atctgacaat cgtctgttca cgatccggtc ctacggaaac gatcttcaca
     2821 ggcacaccca gttcttcctc caagaaagaa aggtaagcgt tgaactcctc cgggaactcg
     2881 tcctcgctct gcatcttcgt catgtccgtc ttccaacccg gtaactccac gtatacaggt
     2941 tcgatcgtat catcgatctc atacgggaac tcattagtct cgacaccatt catcttataa
     3001 gccacgcaag ccttgatcgt atcgaaggta tccaacacat cactcttcat catgatcaat
     3061 tggcttacac cgttgatcat cacggcatat ttcaaggcta ccaaatcaat ccagccacaa
     3121 cgacgtttac gtcccgtaac cgcaccgaac tcatggccta attgaccgat cttatctccc
     3181 acctcatcaa acaactcggt cgggaacgga ccgctaccta cacgtgtaca ataagccttg
     3241 aagattccat atacctcacc gatattccgg ggagaaaccc ccagtcccgt acaacatccg
     3301 gcacagatcg tgttagagga agtcacgaat ggataagaac cgaagtctat atccagcatc
     3361 gtaccttgag cgccttccgc caagaccgac ttaccttcct tcaaatagtt attgatgaca
     3421 tgctcgctat caatcaattt gaattgtttg aggtagttca aggcctccat ccattgagcc
     3481 tccatctcgg ttatatcata ttcatagttc aatgaacgca agatcgcttc atgttttgct
     3541 ttagcggccg catatttctc ttcgaagtta tgcaataaat cgcccacacg aacaccgtta
     3601 cggctaatct tatccgtata agtcgggccg ataccctttc ctgtcgtacc gatctttccg
     3661 gaaccttttg cggcctcata agcggcatcc aagatccggt gagtaggtaa aattaggtga
     3721 gctttcttag agatataaag ctgcttggtg atatcgtgac cactcgctgc caatgattcc
     3781 gcttcctgct tgaacaataa cgggtccaga acgacaccgt taccgattac gtttattttt
     3841 ccaccttgga aaataccgga aggaatcgaa cgtaacacat acttttcccc gttaaactcc
     3901 aatgtatgtc cggcattagg gcctccttga aaacgagtta ccacatcgta attcggagtc
     3961 agcacatcga caaccttgcc tttgccctcg tcgccccatt gcaatcctaa caaaacgtct
     4021 actttcatct tttctatatt tattataggc tattaatatt cttatttaac tgacctttgc
     4081 tgcttaaact tgcatttact gcacaggcca taaatgtaca aacaataata ctccggcgta
     4141 aaacgagaga ctttcaagtt tctcatatcc gctttcaacg cactatttcg cagctcccgc
     4201 atggtcccgc atctcgtaca aaccaaatgc aaatgcgtat cagcataaat cctcaactca
     4261 tattgcaccg actggacggt tatttgatga cgcaccacca aaccggcatc aaccagtaca
     4321 tccaacgtat tatagagtgt tgccttactg acatggaagt tgtcttgctc caaccgatcc
     4381 gaaagcatac acacatcaaa atgaccggga aaagcacata tctccttgaa tatagcatat
     4441 ctctcctcgg ttttccgcag tttcttctcc gttagatatt cggtaaacaa cgcacgtatt
     4501 tccgtataaa ctttcgcttc catctcctaa agaccgcaca aacgacaaag ttagcgcatt
     4561 tattttaaac gcaaagcctt accgataata ttcaaactcg aattttaatt cattatagat
     4621 ttcttgtaat tccggcgtgt ttcccgcagc ctcctgaaat tccttgaaac cgtctaggat
     4681 cctttccgca ttcccctcgg attgacgccc ataaaacttc atggcttgaa tagacgcttg
     4741 tttctctttc agcgtagatt taaaatcctt agtctccgct agactactta aggtttctgc
     4801 caagaaagat cctaaaacca cagaagataa gctgccacct cgcttgaaat tctcggccca
     4861 agtaagaaag gcgaccgtgc gagcgaactc atttttctta tcagcaacca gatcagacgt
     4921 gaagtcctcc atataaggca gatgaacgaa caagttccgg caacaatgct ccgcgatctc
     4981 taaataagga atctccttga cccaacgttt cgcctcatcc aaaggcaacg tctcggcggg
     5041 ttggagaaag gtcgccaata tcttaaactc acggatgtct tctttccata aagccgccgc
     5101 tagctctcca ttcggtttat gcttacgggc gattcccttt atttcggggt acggaacccc
     5161 gaaatttaac ttatatacga tacctttctc acgcatactc gtagaaatca ccccgttcat
     5221 cgccaaacga agttccttac ggatctccct tatctcgtct tgtaaacttt ccatctatta
     5281 attattataa gtcggcaaga aagaataatc acggccataa cgaagcatct gatctgtata
     5341 accttccgtg tagtccaaga caatatcagt aacctcaccg ttagagttct ttacctcttt
     5401 catcacagga ttgacaaaac ctttataggg agccaagttt aacttagcat agcgctccaa
     5461 gacctccgca tgcagctccg gatctacttt cacgccgtat ccttcaacaa gattctttcc
     5521 ggccgcatag tcaccctcac tcttgatacg ttgaatctca gcaagcaatg tcccaaacaa
     5581 ctcacgtaac ctcggatagt cattcacaac cacataggtc ttgccatccc gttttttcag
     5641 ttcgatcaca ttcgcttcct tccctttctc gtaagcccac ttagcgatca actgacggtt
     5701 acgcatatgc gcctcttcta cattcttgcc tagctcgatg cgaaccaact gggtcatcaa
     5761 gccattcatt atatatttat agtattccga tttataagcc tcgccgtccg gaagcaatcc
     5821 cagttccacc agctttggat ctgccaaata atacaggcca aacaaatccg cacgggtttc
     5881 ctccagtgta gagctatagg ctttcagcgc atccgggtcc gtattttcca gcaatttacc
     5941 ggaaccatgt cccagacact catgtaaatc cgtatgtaga ttatccgtta agaaaccgta
     6001 ctgcctcata ccgttccgct ccacgtcact ccaaacaaac tcttcgctaa agccatttcc
     6061 ttgagacgcc ttatcataag cctccgtgat attctctatc gtaacagact tcgagccatg
     6121 atccctacga atccaatccg catttggcaa attgataccg atcggggtag ccggatagca
     6181 atcacctccc aacatagata ccgtgattac cttagcgcta actcctttca ccttctcttt
     6241 cttgaaacgc ttatctaccg gagaatgatc ctcaaaccat tgcgcattat cactgatgat
     6301 ttttgtacgc ttagtcgcct ccttattcgt aaaattcacg gtagactccc agcttgcttt
     6361 cattcctaac ggatccccat aagtctcgat aaagccattc acaaaatcca cctccgaagc
     6421 tgtatcctct acccaaagga tcgaataagc atcgaaagtc ttcaaatcgc ccgtttgata
     6481 atattcgatc aatttcccga tgatcgcttt ctgcgtatca ttctcggcga aaggcaaggc
     6541 ttgtcgcaat tgatctacga ttttttctat cgcggcggaa taaagccctc ctactttcca
     6601 aaccttttca acgaccgtac cgttctcttt taccaaacgg ctattcaacc cgtaagaaat
     6661 cggggaaatg gtatcctttc ccattttcat ttgcgcatag aagtcctcta cctctttttg
     6721 actgatgcct cccccgtaat aattattaga agaagctttg atcagatcac cgtcaccgct
     6781 ttgtacgcta cgctttggca taacgcccgg atcaaagatt accggagcga tctcgatcat
     6841 gaattgatcc acgttttgat tctcacgaag aggtaacttc ttagcgtcga tttggtgaat
     6901 acaatccatc aagaactcag gagaaaaccc cggggcaaac ttgtccaacg cataatgatg
     6961 atggatacca ctggagaacc acacccgttt caaataggtt tccaaagcct tgaattgagg
     7021 gtcctcccga tctcccttat aattcgtata aatagcctcc agtgtcctgc ggatcgccag
     7081 attatagcgt ccattctgat cgaagaatat atcacgtccc atcaaggccg cttcggaaag
     7141 atgatataat agttgctttt gttgcaagga cagggactca aaacccggaa ctttatagcg
     7201 aagaatctcc agatcagcga actgatccac tacataattg aactccttat cggaattttg
     7261 agatgccgta tccgactgtt ggcctgtaca agccgtcata accatagctg tcataagcga
     7321 taacattatt tttttcatac ttactacgat ttgcttttcc tataatatat tacatctaaa
     7381 gtacatagtt tgaaggcccg cattccaata agggccaacc gcaaagatag agaatataca
     7441 gtcaatatca aaggtttgag attttttctc tacttttgta agttcaaaag caaagacaaa
     7501 aaagagaatg gaaatagcgg cattagtttc aggaggagta gacagctctg tcgtagtgca
     7561 tcaactcaaa gaggcaggat acgatccgac catcttctat atccgtatcg gtatggaaga
     7621 caaggatggc tatatcgatt gcccggcgga agaggatatc gagatcacct catatatcgc
     7681 ccgcaagtat ggatgccggt tcgagatcgt ctccctacac gacgagtatt gggatcgggt
     7741 ggtaagctat acgatcgaat ctgtcaaacg cggtcttacc cctaacccgg atatgatgtg
     7801 taataaatat atcaagttcg gttgtttcga ggaaaaatgg ggcaaggatt tcgataagat
     7861 cgctaccggt cattatgcca cgaccacgga gatagacggc aagatatggc tttctaccgc
     7921 caaggacccg gtaaaagatc agactgattt cttagggcaa atcacccgcc tacagataca
     7981 gaaactcatg tttccgatcg ggcatttaat gaaaagtgag gtacgtgcca tcgccgaggc
     8041 ccagaaattg ccgagcgcca agcgtaaaga tagccaaggc atttgcttct taggcaagat
     8101 taactacaac gactttatag agcgttattt agggaaacgc ccgggaaaaa tcgtggaact
     8161 agagacgggt aaggtcttgg gtaaacacaa tggatattgg ttccatacga tcggccaacg
     8221 taagggattg ggattaagtg gcggcccttg gttcgttatc caaaaagaca ttaagcgaaa
     8281 tatcatttat gtctccaacg gctacgaccc ggaaacgcaa tatggcaagg tgattaatat
     8341 gcaaggtttc gatttcatca cggaagatcc atggggagaa tttgagggtg agaaagaaat
     8401 cactttcaag atccgtcata ccccggaatt tacgcatggc tacatccgtc gtatcggaga
     8461 tctatatcgt gtagaatccg acgaaaagat tcaaggtatc gctcccggcc aatacagtgt
     8521 aatctacgac aaagaccatc acttatgtct gggcagcggc atgattattg atgagaccaa
     8581 gtaacgcata ttcagattta ttctaaataa aaaacggtcg cctcaaaagg aagcgaccgt
     8641 ttttattttt ctatcttatt ctattaaata gcatacaaag agctgataga ctctccacta
     8701 catacacgac ggatcgcctc agcgaacatg tcagcgacag ataatacctt tactttctcg
     8761 catttcttag cgtaaggaat agaatccgta aagatcattt ccgctaaagc ggactgatct
     8821 acacgagtag aagccggatc agacatcaca gcgtggctgg cgatagcacg aacagactta
     8881 gcgccattct ccaacatcaa gttcgcggct ttcgtaattg ttccggccgt atccaccatg
     8941 tcatcaacca aaaggacatc caagcccgtc acatcaccga taatacgcat ctcggccacc
     9001 tcattggcac gcaaacgaga tttgtggcaa atgaccatcg gcaagcctaa atacttagaa
     9061 tagctgctgg cacgtttcgt accaccaaca tccggagtcg cgatacacaa gttatccaaa
     9121 ggcaaagacg tcttgatata atccaagaat acggaagaag catataagtg atccaccgga
     9181 acattaaaga atccttggat ctgatccgca tgaaggtcca tcgtaatcaa acgattgata
     9241 cctgccgtac tcaacatatc agcgatcaac ttagcgccaa tagaaacacg aggcttatcc
     9301 tttctatcct gacgagccca accgaagtaa gggactacag cgatgattga atgtgcggaa
     9361 gcacgtttag ccgcgtcaat catcagaagc aactccatca gattgtctga attagggaat
     9421 gtagattgta ctaagaatac atctctaccg cggatagact cttcataaga aacagagaac
     9481 tcaccatcgg caaagtgctg gatattcatc tgtcccagag gacaacctaa actgttgcaa
     9541 attttctctg caagataccg ggagttcgtt cccgaaaaca ccaagaaagg agtttgtgca
     9601 ctcattattc cgaatattta tcttaaagtg aatagattta aattgtgccg caaaagtaca
     9661 aaacttattt acaataacct ctttatattt ggaaaacttt ctatatttgc aaccgcaatg
     9721 atgaagtatt tactctattt cttcgtattg gtaagtgtat ttctgacttc gggttcttca
     9781 tcaactcccg agaaccaaca gaaatacaac gatatttaca ccatgtactc tccgaatgaa
     9841 gacaagacgg aatacaatat cccccaagca gatatcgaac gatacgaaaa agagctatac
     9901 aacggaaaac aaagctataa gatggaagat ggctatatca gggcttcact attccgcaac
     9961 atctccacat caaaaaactc aaggacaaac ctatcctcat ccgcggaaag gatcgtacgg
    10021 tttataaaaa ctcaatatcc taaagaaaga caaacattca tttcattttg tataaatccc
    10081 cttaagttct cctatgggta ctatatctat actctaagac gtattctcat ttaaactctc
    10141 tttccccctt atttccatca aaaaagtaga agatagcact ttaatgtctg cattctcact
    10201 attcttattt tctagatttc tcaaagggaa tagaataaac atctattttg ttttcttatt
    10261 gggtcatata ggatagttct tatcaattaa taatcaatct aaaatggaat ttttattaga
    10321 cttcatctta catatcgatc agcatatgat cgagatcgta caagaatatc atacttgggc
    10381 ctacgcgata ttattcctaa tcattttttg tgaaacggga ttggtagcca ccccattctt
    10441 gcccggggat tccctcttgt tcgtcgccgg agcgataaca gcgttacccg gtatgccttt
    10501 agagataaat cttttagcct tgatattatt cgcggcggca gtattgggag actcctgtaa
    10561 ttatatgata ggtcattttt ttggtcgtaa actatttaac aatcccaact ccaagatatt
    10621 caagaaaagc catttggaca aaacgcatga gttctacaaa aaatatggag gcaaaaccat
    10681 aatcatcgcc cgattcgtac cgattgtccg tactttcgct ccctttgtag ccggaatggg
    10741 taaaatgcac tattactatt tcatgatcta caacctgata ggcggcgctt tctgggtact
    10801 gcttttctgc tatgcaggat actttttcgg agatcttcct ttcgtacagc agaacctcaa
    10861 gctattgatc atagcaatta tattcatatc catacttcct gccgtaatag aggtagtacg
    10921 ggcaaaacta aaagcacgga aa
//
LOCUS       DBMDTB010000118        10554 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_1838_length_10554_cov_11.190950, whole genome shotgun
            sequence.
ACCESSION   DBMDTB010000118 DBMDTB010000000
VERSION     DBMDTB010000118.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 10554)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 10554)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10554
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1838_length_10554_cov_11.190950"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            127..708
                     /locus_tag="ACZPB4_14640"
     CDS             127..708
                     /locus_tag="ACZPB4_14640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HIR1099489.1"
                     /translation="MDTAIFIARRIAAQSILLSEEAVEKLASILIRTELKKGALFLSE
                     GEVCTQLGYVYKGMVRQFYFKNKKELTEHFASEDNIFICIESFLRQRPANLLVEALEN
                     TVLYGIPHDPLLALCAEDYEIEVMYRRLLENSLILSQRKADFLRFETANERYARLLKE
                     HPEIVQRAPLSHIASYLLMTPETLSRVRANMQL"
     gene            770..1510
                     /locus_tag="ACZPB4_14645"
     CDS             770..1510
                     /locus_tag="ACZPB4_14645"
                     /EC_number="1.5.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005924719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(Fe-S)-binding protein"
                     /protein_id="HIR1099490.1"
                     /translation="MKVGLFIPCYINAVYPEVGIASYKLLKHVGVDVDYPMDQTCCGQ
                     PMANAGFEDEAARLALRMEEQFKNYDYVVGPSASCVAFVKENHPHILGKRDHVCMNSK
                     KIYDICEFLHDVVRPESLPAVFPHKVSIHNSCHGVRELHLSSPSERNIPYYSKLRDLL
                     SLVKGIEVFEPKRVDECCGFGGMFAIEEPEVSTCMGQDKVKDHMSTGAEYITGADSSC
                     LMHMEGVIKREKLPIKTIHIVQILASGL"
     gene            1507..2874
                     /locus_tag="ACZPB4_14650"
     CDS             1507..2874
                     /locus_tag="ACZPB4_14650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein B"
                     /protein_id="HIR1099491.1"
                     /translation="MSTKHAIAAARFLENKENEAWHDHTLWMVRTKRDKMSHSLPEWE
                     RLRELASEIKLYSNSHLDTLLEEFEKNAIANGAIVHWAKDAEEHNEIVLRILRQHDAR
                     NLIKSKSMLTEECHMNEFLMSKGIDVVESDLGERILQLMHLAPSHIVMPAIHIKREQI
                     SEMMEREMGTEKGNIDPTYLTHAVRKNLREKFLHADVAMTGANFAVASTGEIVVCTNE
                     GNADMGTSFPKVHIATMGMEKIVPNLEALGVFTRLLARSGTGQPITSYTSHYRRPSEG
                     QEFHIIIVDNGRSDILAKPDHIRTLNCIRCGECMNTCPVYRRSGGYSYTYFIPGPIGI
                     NLGMLRNPEEYSDNVSACSLCLSCSNVCPVKIDLGEQIYRWRQDLDKIGKASKEKKVM
                     SFGMKFLMERPGLFNTALKFAPVVNHLPRFMVYNGLNAWGKGRELPTFAKESFNDMWK
                     NNKVR"
     gene            2874..3452
                     /locus_tag="ACZPB4_14655"
     CDS             2874..3452
                     /locus_tag="ACZPB4_14655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006089 - lactate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LutC/YkgG family protein"
                     /protein_id="HIR1099492.1"
                     /translation="MSSKDSILASIRRHTGARHEMPELTLEAITYADKLATFSEVLAG
                     AGGKAIELKPGEDVNEVIRREFPEAKRIASNLKEITCSTFNPDELTDPRELNGTDVSV
                     VEGSFGVAENAAVWLPRQVRYKGLYFISNALVILLDKTQLVHTMNEAYRRTATMDYDY
                     GVFMSGPSKTADIEQALVFGAHGPIRVVVLLR"
     gene            complement(3511..4653)
                     /locus_tag="ACZPB4_14660"
     CDS             complement(3511..4653)
                     /locus_tag="ACZPB4_14660"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0018455 - alcohol dehydrogenase [NAD(P)+]
                     activity [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HIR1099493.1"
                     /translation="MNNFTFHNPTRLLFGKGMIEKLSTAIPMVHRIMITFGGGSVKQN
                     GVYDQVIKALKDRDYIEFWGIEPNPTIETLREAIQIAKGKQVDFLLAVGGGSVIDGTK
                     LISAGIQYDGDPWELVQKGYYYHTVPMGTVLTLPATGSEMNSGTVISRKETQEKFPFY
                     SNFPVFSILDPETTFSLPPYQVACGIADTFVHVMEQYMTTTDQSRLMDHWAESILSTL
                     VEIAPKIKEDSRNYDLMADFMLSATMGLNGFIAMGVTQDWATHMIGHELTALHGLTHG
                     ATLAIVLPGTLRTLRKQKEGKILQYGERVWGINSGTTEERVSQAIEKTEQFFQSLGLS
                     TRLSQEKIGDTTITEIENRFNERNAAFGEAKNVTGSVAREILESCK"
     gene            complement(4696..5469)
                     /gene="trpA"
                     /locus_tag="ACZPB4_14665"
     CDS             complement(4696..5469)
                     /gene="trpA"
                     /locus_tag="ACZPB4_14665"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - L-tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HIR1099494.1"
                     /translation="MNRITNLFQTQKDGILSVYFTAGYPNLNDTASILKALQAKGIHM
                     VEVGIPFSDPMADGPVIQEAATQALRNGMSLHLLFEQLKEIRSEVQIPIILMGYLNPI
                     MQYGFEKFCASCVEAGVDGMIIPDLPYADYISDYKEIADRHDLKMIMLITPETSEERI
                     RQIDAHTSGFIYMVSSAATTGAQQDFNEQKQAYFRRINAMNLQNPRLVGFGISNKATF
                     EAATAHSSGAIIGSKFVQLLKSEATPAEAVDKLLEALKQ"
     gene            complement(5495..6160)
                     /locus_tag="ACZPB4_14670"
     CDS             complement(5495..6160)
                     /locus_tag="ACZPB4_14670"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004640 - phosphoribosylanthranilate
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000162 - L-tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HIR1099495.1"
                     /translation="MIIKVCGMREPQNIREVAALAINWIGFIFYERSKRFVERCPTEQ
                     QVTDSEQLSPKKVGVFVNATIESMMEKASAYKLDYLQLHGNESPEDCHTLQKRGYSLI
                     KAFPIATKEDFEKTREYEGRVDYFLFDTRCEGYGGSGKRFDWSILTEYKGETPFLLGG
                     GIRPENAEAIRNFRHPRLAGIDLNSGFEIEPGLKDVDKLKNFIQQILHPAVETGRAPS
                     PTV"
     gene            complement(6157..6951)
                     /gene="trpC"
                     /locus_tag="ACZPB4_14675"
     CDS             complement(6157..6951)
                     /gene="trpC"
                     /locus_tag="ACZPB4_14675"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004425 - indole-3-glycerol-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006568 - L-tryptophan metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HIR1099496.1"
                     /translation="MKKDILQDIIANKRIEVARQKQAVSLQTLLALGSDRMERDTRSM
                     RAALESSPSGIISEFKRKSPSKGWLHPGANIADVVPAYEAGGASACSILTDGDFFGGS
                     LGDLQKARKLVDLPLLRKDFIIDTYQLFQARVMGADAVLLIAAALTEEECRILAETAH
                     SLQLEVLLEVHSEDELKYLNADIDMLGVNNRNLGTFHTDVNNSFKLVDKMRGFSPLLV
                     SESGISETDTVRQLREAGFRGFLIGETFMKTERPGDTLADFIGGLA"
     gene            complement(6968..7963)
                     /gene="trpD"
                     /locus_tag="ACZPB4_14680"
     CDS             complement(6968..7963)
                     /gene="trpD"
                     /locus_tag="ACZPB4_14680"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004048 - anthranilate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0000162 - L-tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HIR1099497.1"
                     /translation="MKQILYRLFEHQYLGREEARNILQNIAEGRYNDSQIASLITVFL
                     MRSISVEELTGFREALLEMRVPVDLSEYKPIDIVGTGGDGKNTFNISTCSCFVVAGAG
                     YHVVKHGNYGATSVSGASNVMEQHGVKFTNDIDKLRTSMDTCHIAYLHAPLFNPALKA
                     VAPVRKSLGVRSFFNMLGPLVNPVMPTYQLLGVYNLPLLRLYNYTYQESGTRFAVVHS
                     LDGYDEISLTADFKVAMPEKEKLYTPEMLGFKRCTEADLDGGETPEEAARIFDAVLGN
                     RATEAQKSCVIANSAFAIQVICPEKKIETCIAEARESLESGKALATFRKFISLNH"
     gene            complement(8133..8699)
                     /locus_tag="ACZPB4_14685"
     CDS             complement(8133..8699)
                     /locus_tag="ACZPB4_14685"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004049 - anthranilate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - L-tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component II"
                     /protein_id="HIR1099498.1"
                     /translation="MKILLFDNYDSFTYNLLHILKELGADVEVHRNDKISLEEIERFD
                     KILLSPGPGIPEEAGILLPLIRRYAPTKSILGVCLGEQAIGEAFGATLINLTDVHHGV
                     CSDIRIVAKDPIFEGLEPGIRVGRYHSWAVSKENFPDCLEITAVDTEEGQIMGLRHRE
                     YDVRGIQFHPESVLTPKGKTIIENWLKR"
     gene            complement(8822..10225)
                     /locus_tag="ACZPB4_14690"
     CDS             complement(8822..10225)
                     /locus_tag="ACZPB4_14690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I family
                     protein"
                     /protein_id="HIR1099499.1"
                     /translation="MNYSFKTISKKVMGDLHTPVSIYLKVRDIYPESALLESSDFHGN
                     ENSLSFIALRPLASIGINNGECTATFPDETREVTPLTEDYNVPEAMNAFLGRFKVEGA
                     DKKVCGLFGYTAFDAVRYFENIPVMEVHHEENDAPDMLYILYKYILVFNHFKNELTLV
                     EMLQEDEASRLEEIETLIENRNFASYNFQTAGPETSPITGEEYKAMVRQGIKHCLRGD
                     VFQIVLSRRFEQPFKGDDFKVYRALRSINPSPYLFYFDFGGFRIFGSSPETHCKVTGR
                     HASIDPIAGTAFRTGNIEVDKQRTEALLADPKENAEHVMLVDLARNDLSRNAHDVQVD
                     FYKEVQYYSHVIHLVSRVSGEINTDSDPVKTYVDTFPAGTLSGAPKVRAMQLITDIEH
                     HNRGAYGGCIGFIGLDGDLNQAITIRTFVSRGNVLYYQAGAGIVAKSNDERELQEVNN
                     KLGALKKAIDLAEKLIN"
     gene            complement(10222..>10554)
                     /locus_tag="ACZPB4_14695"
     CDS             complement(10222..>10554)
                     /locus_tag="ACZPB4_14695"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772462.1"
                     /note="catalyzes the formation of L-tryptophan from
                     L-serine and 1-(indol-3-yl)glycerol 3-phosphate; Derived
                     by automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HIR1099500.1"
                     /translation="GARTLVMQNEDGQIEEPYSVSAGLDYPGIGPIHANLSVKHRAQI
                     LAVDDDEALEAAFELTRLEGIIPALESAHALGALAKVNFKPEEVVVLTVSGRGDKDMD
                     TYINYKLS"
BASE COUNT         2374 a         2545 c         2860 g         2775 t
ORIGIN      
        1 tgtaatggct tcacggatta tcgccacttc aaccaaaacc cttgtaactc aattctatca
       61 ctatatcttt ccgcatttca cttttttgta gtaactttgc ggaaacaaac aaaaacaacc
      121 atgaatatgg atacagcgat atttatagct cgcaggatcg cggcgcaatc gattctactc
      181 agtgaggaag ctgttgagaa actggcctct atcttaatcc ggacagaatt gaaaaaaggc
      241 gccctgtttt tgagcgaagg agaggtttgt acgcaactcg gttatgtcta taagggaatg
      301 gttcgccagt tttacttcaa gaataagaaa gagctgaccg agcatttcgc cagcgaggac
      361 aacatcttca tttgcatcga gagcttcttg cgccaacgtc ccgctaatct gttggtggag
      421 gccttggaga atacggtact gtatggcatt cctcatgatc ctttattggc attgtgcgcc
      481 gaggattacg agatcgaggt catgtatcgc cgcttgttgg agaattcgct gatcctgtct
      541 caacggaaag cggatttcct tcgtttcgag accgctaatg aacgttatgc ccgcttattg
      601 aaagaacacc ctgagatcgt gcagcgtgcc cccttgtccc atatcgcttc ttatttgttg
      661 atgactcccg agacgttgag ccgggttagg gcaaatatgc agttgtgatg ggcctttagg
      721 tgttaattat atacggtgtc gtatataagg atataaagat ataattagta tgaaggtagg
      781 attatttatc ccatgttaca ttaacgcggt gtatcccgaa gtgggtatcg cctcgtataa
      841 attgttgaag catgtgggtg tggatgtcga ttatccgatg gaccagacct gctgcggaca
      901 acccatggcg aacgccggct tcgaggatga ggcggctcgc ttggccctcc ggatggagga
      961 acagtttaag aactatgact acgtggtagg cccctcggcc agttgcgtag ccttcgtaaa
     1021 agagaaccat ccccatatat tgggaaagcg ggatcacgtt tgtatgaaca gtaagaagat
     1081 ttatgatatc tgcgagttct tgcacgacgt ggtgagaccg gaatccctgc cggccgtttt
     1141 cccgcataag gtgagtatcc ataatagttg ccacggggtg cgtgagttgc atctctcgtc
     1201 gcctagcgag cgtaatatcc cgtactattc caagttacgt gatctccttt ccttggtgaa
     1261 aggtatcgag gtgttcgagc cgaagcgggt ggacgaatgt tgcggtttcg gcggtatgtt
     1321 cgccatcgag gagcctgagg tctctacttg catgggacaa gacaaggtaa aggatcatat
     1381 gagtaccggc gccgagtata tcaccggggc ggatagctct tgcctgatgc atatggaagg
     1441 ggttatcaag cgggagaaac ttccgatcaa gactattcac atcgttcaaa tattagcgtc
     1501 cggattatga gtacgaaaca tgctatagca gcggcccgtt tcctagagaa taaggaaaat
     1561 gaggcttggc acgaccatac gctttggatg gtacgtacca aacgggataa gatgagccat
     1621 tcgcttcccg agtgggagcg gttgagagag ttagcctcgg agatcaagct ttactccaac
     1681 agccatctgg acacgcttct ggaggagttc gagaaaaacg cgatcgccaa cggggctatc
     1741 gtgcactggg cgaaagatgc cgaggagcat aacgagatcg tcttgcggat cttgcggcag
     1801 catgatgccc ggaacctaat caagagcaaa tcgatgctga cggaggaatg ccatatgaat
     1861 gagttcttga tgtcgaaagg aatcgatgtg gtggagagcg atttgggtga gcgtatcttg
     1921 caattgatgc atttggcccc gagccatatc gtgatgccgg cgatccatat caaacgggag
     1981 cagatcagcg agatgatgga gcgtgagatg ggaacggaga aagggaatat cgaccctacc
     2041 tacctgacgc atgccgtccg taagaatctg cgtgagaaat tcctgcatgc cgacgtggcg
     2101 atgacgggcg ctaacttcgc cgtcgcctct acgggcgaga tcgtggtttg taccaatgag
     2161 ggaaacgccg atatgggaac ctccttcccg aaggtgcata tcgctacgat ggggatggag
     2221 aagatcgtac cgaatctgga ggcattgggc gtattcactc gtttgctggc tcgttcgggt
     2281 acggggcaac ccatcacgtc ttatacttcc cattatcgcc gtccgtccga gggacaagag
     2341 ttccatatca ttatcgtgga taacgggcgt agtgatatct tggcgaaacc ggatcatatt
     2401 cgtacgttga attgcatccg ttgtggcgag tgcatgaata cctgtccggt atatcgcagg
     2461 agtggtggct attcgtatac gtatttcatt ccgggaccga tcgggatcaa cttgggtatg
     2521 ctgaggaatc cggaggaata ttcggataac gtatcggctt gctccttatg tctttcttgc
     2581 tcgaacgttt gtccggtaaa gatcgatttg ggcgagcaga tttaccgttg gcgacaagat
     2641 ttggataaga tcggtaaggc gagcaaggag aagaaagtga tgtctttcgg catgaagttc
     2701 ttgatggaac gtccgggatt gttcaatacg gcgttgaagt ttgctccggt agtgaatcat
     2761 ttgccccgtt tcatggtcta caatggcttg aacgcttggg gcaagggacg tgagcttccg
     2821 actttcgcca aggagtcgtt taatgatatg tggaagaata ataaggtgag ataatgagta
     2881 gtaaagattc tatattggcg agtatccgtc gtcatacggg tgcacgccac gagatgcctg
     2941 agcttacgtt ggaggcgatt acctatgcgg ataagttggc tacgttctcg gaggtgttag
     3001 ccggggcggg tggcaaggcc atcgagttaa agcccggcga ggatgtgaat gaggtgatcc
     3061 gccgtgagtt tccggaggcg aaacgtatcg cctcgaattt gaaggagatt acttgctcta
     3121 cctttaaccc ggatgagctg accgatcccc gggagttgaa cgggacggac gtatctgtgg
     3181 tggagggtag tttcggcgtg gcggagaatg ccgctgtctg gttaccccgt caggtacgtt
     3241 ataaaggtct gtactttatc tcgaacgctt tggtgatctt gttggacaag actcaattgg
     3301 ttcatacgat gaatgaggct taccgccgta ctgccactat ggattatgat tacggagtct
     3361 tcatgtccgg tccctcaaag actgctgata ttgaacaagc cttggtattc ggggcgcatg
     3421 gcccgatccg ggtagtagtc ctgttaagat aaaatctata cccttttgag gggatgagac
     3481 ggggcacgcc ccgtctctac aagttgtacg ttatttacag ctctccaata tttcccgtgc
     3541 cacgctaccc gttacattct tcgcctcccc gaaggcggcg tttcgttcat tgaagcgatt
     3601 ctcgatctcg gtgattgtcg tatcgccgat cttctcttgg ctgaggcggg tagataaacc
     3661 gaggctttgg aaaaattgct cagtcttctc gatggcttgg cttacccgtt cttctgtcgt
     3721 tccactattg ataccccata cccgttcgcc gtattgcagg atcttgccct ctttctgctt
     3781 gcgtagggtg cgtaaggttc cggggaggac gatcgctaag gtcgctccat gcgtcaatcc
     3841 gtgaagggcg gttagctcgt gtccgatcat atgggtagcc cagtcctgcg ttacgcccat
     3901 agcgataaag ccgttcaagc ccatcgtggc ggatagcatg aaatctgcca tcaggtcgta
     3961 attcctcgaa tcttccttga tcttcggggc gatctcaacc aaggtgctta aaatactttc
     4021 cgcccaatga tccatcaagc gggattggtc ggtcgtagtc atatattgtt ccatcacgtg
     4081 gacgaaggta tcggcgatac cgcaagccac ttgatacggg ggcaggctga aggtcgtctc
     4141 cggatccaag atcgagaata cggggaaatt gctgtagaac gggaatttct cttgcgtctc
     4201 tttccgggag atcacggtcc cgctattcat ctcggaacct gtggcgggca gggtcagtac
     4261 ggtacccatg ggcacggtat gatagtaata ccctttctgt accaattccc aaggatcacc
     4321 gtcgtactgg atgccggcgg agattagctt cgtcccgtct atgacggagc caccgcctac
     4381 cgccaatagg aaatccacct gcttgccttt cgctatctgg atagcttctc gcaaggtctc
     4441 gatggtggga ttaggctcga tgccccagaa ctcgatatag tcacgatcct ttagcgcctt
     4501 gatcacttgg tcgtacacac cgttttgctt tacgctacct cctccaaaag tgatcatgat
     4561 gcgatgcacc atcgggatgg ccgtactcag tttctcaatc atgcccttac cgaataataa
     4621 acgggttggg ttgtgaaaag tgaagttatt cataggacta tttactgttt ttatatgtaa
     4681 acatgaatag ggttcctatt gttttagggc ttccagtaac ttatcgaccg cctcggcggg
     4741 agtagcttcg ctctttagta actggacgaa cttgctaccg atgatggcac cggaagaatg
     4801 ggctgtcgcc gcctcgaaag tggctttatt gctgatgccg aaacctacca agcggggatt
     4861 ctgtaggttc atggcgttga tacgacggaa ataggcctgc ttttgttcgt tgaagtcttg
     4921 ttgggctccg gtcgtggcgg cgctggatac catatagata aatccgctgg tatgggcatc
     4981 gatctgccgg attcgttcct cggaggtctc tggggtgatc agcatgatca tttttaggtc
     5041 atggcgatcg gcgatttcct tgtaatcgga gatataatcg gcgtaaggca ggtcggggat
     5101 gatcattccg tctacgccgg cctctacgca actggcgcag aatttctcga aaccgtattg
     5161 catgatgggg ttcaggtagc ccatcaagat gatcgggatc tgtacttcgc tccggatctc
     5221 tttcaattgc tcgaatagga ggtgcagtga catcccgtta cgcaacgctt gcgtggcggc
     5281 ctcttggatg acggggccgt ctgccatcgg gtcggagaaa gggattccta cttctaccat
     5341 gtggatacct ttagcctgta aggcttttaa gatgcttgcc gtatcgttta agttcggata
     5401 accggcggtg aaatagacgg agagtattcc gtctttctgg gtctggaata agtttgtgat
     5461 gcgattcatt ttgaattcta ttttaaaaat actatcagac ggtgggagac ggggcacgcc
     5521 ctgtctctac agctggatgt aaaatttgtt ggatgaaatt ctttagtttg tcgacgtctt
     5581 tcaatcccgg ctcaatctcg aagccactgt tgaggtcgat acctgcgaga cggggatgcc
     5641 ggaagttccg gatcgcctct gcgttttccg gacggatgcc tccgccgagc aagaagggag
     5701 tctctccttt atattcggtt aggatggacc aatcgaaacg tttgcctgag cctccatagc
     5761 cctcgcatct cgtatcgaaa aggaaataat ccacccggcc ctcatactcc cttgtttttt
     5821 cgaagtcctc tttcgtagcg atggggaaag ccttgatcaa ggaatagccc cttttttgca
     5881 aggtgtggca atcttccggc gattcgttac cgtgaagttg gagatagtct agcttgtagg
     5941 cggaggcttt ctccatcatg gactcgatgg tagcgttgac gaaaacgccc actttcttag
     6001 gggacaattg ttcactgtcc gttacctgtt gctccgtcgg gcatcgctcg acaaagcgct
     6061 tggaacgttc gtagaagata aagccgatcc agttgatggc tagggcggct acttcccgga
     6121 tattctgagg ttcccgcatt ccgcaaactt tgatgatcat gccagtcctc ctataaaatc
     6181 ggctagggta tcgcccggcc tctcggtttt catgaaggtc tctccgatca ggaatccacg
     6241 gaaaccggcc tcacgcaatt ggcgtacggt atcggtctcg gagattccgc tctcggacac
     6301 taaaagaggg gagaagcctc gcatcttatc gaccaacttg aatgagttgt ttacgtccgt
     6361 atggaaggtg ccgagattgc ggttgttcac gccgagcata tcgatatccg cgttcaggta
     6421 tttgagctcg tcctcgctat ggacttccag caagacttcc aattgcaggc tatgggcggt
     6481 ctcggcgagt atccggcatt cttcttccgt aagggcggcg gcgatcaaca agacagcgtc
     6541 ggcacccatc acccgggctt ggaagagttg gtaggtatcg atgatgaagt ccttgcgaag
     6601 taacgggaga tccaccagct tgcgggcctt ttgcaagtcg cccaaggaac ctccgaagaa
     6661 atccccgtcc gtaaggatcg agcaggcgga ggctcctccg gcctcgtaag cgggcaccac
     6721 gtcggcgata ttcgcacccg gatgcagcca gcccttggag gggcttttac gcttgaactc
     6781 ggagataata ccggaggggg atgattccag cgccgcacgc atggaacgtg tgtcacgctc
     6841 catacggtcg ctacctagag ccaataaggt ctgtaagctt acggcctgtt tttgccgggc
     6901 tacctcgatg cgcttattgg cgataatatc ttgtaagatg tcctttttca taggatatgt
     6961 ttctttatca atggttcaaa gatataaatt tacggaatgt agccaatgct tttccgcttt
     7021 ccaatgattc acgtgcctcg gcgatacacg tctcgatctt cttctctgga cagatcactt
     7081 ggatggcgaa ggcggagttg gcgatcacgc agctcttttg ggcctcggta gccctgttcc
     7141 ctaatacggc gtcgaagata cgggccgctt cctccggggt ctcgccgccg tcgaggtccg
     7201 cttccgtgca acgtttgaat ccgagcatct ccggggtata aagcttctct ttctccggca
     7261 tggctacctt gaaatcggcc gtgagggaga tctcgtcgta accgtccaag ctatgtacca
     7321 cggcgaaacg ggtaccgctc tcttgatacg tataattata taggcggagt agcgggaggt
     7381 tatatacgcc taacaattgg taagtaggca tgaccgggtt gaccagcggg ccgagcatat
     7441 tgaagaagct gcgcacgccg aggctcttcc gtaccggagc taccgctttc agcgccgggt
     7501 tgaacaaggg ggcgtggagg taggcgatat ggcaggtatc catggaggta cgtagcttat
     7561 cgatatcgtt cgtgaatttt acgccgtgtt gctccatcac gttgctggcg ccgctcaccg
     7621 aggtagcccc gtagttaccg tgctttacga catggtaacc ggcaccggcc actacgaaac
     7681 aggaacaagt gctgatgttg aacgtgtttt ttccgtcgcc tccggtacct acgatatcga
     7741 tcggtttgta ttcgcttaga tctaccggta cacgcatctc cagcaaagct tcccggaatc
     7801 cggtcaattc ctctacggag atactgcgca tcaggaatac ggtgatcaga ctggcgatct
     7861 gggaatcgtt gtagcgtccc tccgctatat tctggaggat attccgggct tcttcccggc
     7921 ctagatattg gtgctcgaat aatctgtata atatttgctt catgtctgta atgtgttgaa
     7981 tgataaatta ttgcagtttt gcgatatttc tttatcgaaa aacttttgtt tctctagggg
     8041 aaaactcttg tttcttgctt gagaaacatt agtttcacta tagggaaact gatgtttcgt
     8101 taggaagaaa ctataagtgc cttaggaggt aattagcgtt tcagccagtt ctctataatt
     8161 gtcttccctt tgggtgtcaa cacggattcc ggatggaatt ggatacctcg tacatcgtac
     8221 tcacgatggc gcaagcccat gatctgtcct tcttccgtat cgaccgccgt aatttccaga
     8281 caatccggga agttttcctt ggagaccgcc caagaatgat aacgcccaac acgtatacca
     8341 ggttccagtc cctcgaagat aggatcttta gcgacaatcc gtatatcgga gcaaacgccg
     8401 tgatgcacgt cggtaaggtt tatcaatgtg gcgccgaatg cctcgccgat cgcctgctcg
     8461 cctaggcaga cacctaggat gctctttgtc ggggcgtacc ggcggatcaa ggggaggagg
     8521 atgccggctt cctcggggat gcccggtccc ggggatagta agatcttatc gaaacgctct
     8581 atctcttcca aggagatctt gtcgttgcgg tgtacctcta catccgcacc cagttccttc
     8641 aatatatgta gcaaattgta ggtgaaggaa tcgtaattat caaataataa tatcttcatt
     8701 ttatatatat tgttgttgtt gtagagacgg ggcgtgcccc gtctcatcct ttcaaaatgg
     8761 taacttaaaa tactatcaga ctgtgggaga cggggcacgc cccgtctcta caaccggata
     8821 atcaattgat taatttctcc gctagatcta tcgctttctt caaggctccc agcttattgt
     8881 ttacctcttg caattcacgc tcatcgttgc tcttagccac gatcccggct cccgcctgat
     8941 agtaaagtac gttgccacgg ctgacgaagg tacggatcgt gatcgcttgg ttcaaatcac
     9001 cgtccagacc gataaagccg atacagccgc cgtaagcgcc ccggttatga tgctcgatgt
     9061 cagtgatcag ttgcatggcc cgtactttgg gggctccgct caatgtgccg gcggggaagg
     9121 tatcgacgta ggtctttacc gggtcgctat cggtgttgat ctcgccgctc acacgggata
     9181 cgaggtggat gacgtggctg tagtattgta cctccttata gaaatccact tgcacgtcgt
     9241 gggcgttccg gcttaggtcg ttgcgggcga ggtctaccag catcacgtgc tcggcgttct
     9301 ccttgggatc ggcaagcagg gcctcggtac gctgcttgtc tacctcgata ttaccggtac
     9361 ggaaagcggt cccggcgatc gggtcgatgc tggcgtgtct gcccgttacc ttgcaatgcg
     9421 tctcggggga agagccgaag atacggaaac ctccgaaatc gaagtagaac aaataaggag
     9481 agggattgat gctgcgaaga gcccggtaca ccttgaagtc gtctcccttg aacggttgct
     9541 cgaagcgacg gctcaatacg atctggaaga catcccccct gaggcagtgc ttgatgcctt
     9601 ggcggaccat cgccttgtat tcctcgccgg tgatcgggga ggtctcggga cccgctgtct
     9661 ggaagttata ggaggcgaag ttacggttct ctatcaatgt ctcgatttct tccagccggc
     9721 tagcctcgtc ctcttggagc atctccacta gggtcagctc gttcttgaaa tgattgaaga
     9781 caaggatata cttatataat atgtatagca tatcgggggc gtcgttctcc tcgtgatgaa
     9841 cttccatgac cgggatgttc tcgaaataac ggacggcatc gaaagccgtg tagccgaata
     9901 atccgcagac cttcttgtcc gctccctcca ccttgaagcg gccgaggaaa gcgttcatcg
     9961 cctcgggtac gttatagtct tcggtgagcg gggtaacctc acgggtctcg tccgggaagg
    10021 tagccgtgca ttccccgttg ttgataccga tgctcgccaa ggggcggagc gctataaagg
    10081 aaaggctatt ctcgtttccg tggaagtccg agctttccaa cagggccgat tccgggtaga
    10141 tatcccgcac tttcagatag atgcttacgg gagtgtgaag gtcgcccatc accttcttgc
    10201 ttatcgtttt gaaagaataa ttcatgataa tttataatta atgtaagtgt ccatatcttt
    10261 atcgccacgg cccgagacag tcagtaccac cacctcttcc ggcttgaagt ttaccttggc
    10321 caaggctccc aaggcatggg cgctttccaa ggccgggatg attccttcca gacgggtcaa
    10381 ctcgaaagcg gcctccaacg cctcgtcatc atcaaccgct aggatttgcg cacggtgctt
    10441 tacggagagg tttgcgtgga tcgggccgat gcccgggtaa tccaagccgg cggaaacaga
    10501 ataaggttcc tcgatctgtc cgtcctcgtt ctgcatgacc aaggtacgtg cccc
//
LOCUS       DBMDTB010000119        10414 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_1873_length_10414_cov_12.927082, whole genome shotgun
            sequence.
ACCESSION   DBMDTB010000119 DBMDTB010000000
VERSION     DBMDTB010000119.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 10414)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 10414)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10414
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1873_length_10414_cov_12.927082"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..798
                     /locus_tag="ACZPB4_14700"
     CDS             <1..798
                     /locus_tag="ACZPB4_14700"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0046349 - amino sugar biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HIR1099501.1"
                     /translation="IMGLHLEGNYLNMAMKGGQDPNYIYPPDPQEYKELLNSTQCIKR
                     WSAAPELDGALVFGKYASAHGVLVSLAHTTADYLQVKKAYEAGFTHATHFYNAMTSVH
                     KDREYKHEGTVEGIYLMKDMTVEVVADGIHVPPAILKLVYQIKGVERTSLITDAMAAA
                     ACDNGTEHFPDSRVIIEEGVCKLADRSAIAGSIATGIRLIRTLVEKAEIPLHDAVRMA
                     SESPARLMGILDCKGTLEKGKDADIIIFNNDIEIQETFIEGKRLSKE"
     gene            855..1868
                     /locus_tag="ACZPB4_14705"
     CDS             855..1868
                     /locus_tag="ACZPB4_14705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HIR1099502.1"
                     /translation="MYMENVKEHYWRYSLITIILGLGVILFFKITPFLGGILGAFTIY
                     ILLRGQMFHLTEKLNMRPAFAALLLLGETILCFLIPITSAIWLVINKTQNINLDPTVL
                     LNTGQHIADLVQEKTGFDVLDRGNLLKAASILPQIGQFLVGSISSFAVNVVVLIFILY
                     FMLIGGRKMENYLYTLFPFSDQNKDEVLNEINMIVKSNAIGIPLLAVIQGIVAVIGYF
                     IFQTPDPLLFGFLTCIATIIPIVGTALVWVPLAAYMALNGDWVHALGLAIYALLVITN
                     VDNLIRFILQKKLADIHPLITVFGVVIGLSLFGFMGIIFGPLLVSLFLLCIDIFKKSY
                     LDK"
     gene            1940..2797
                     /gene="map"
                     /locus_tag="ACZPB4_14710"
     CDS             1940..2797
                     /gene="map"
                     /locus_tag="ACZPB4_14710"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HIR1099503.1"
                     /translation="MSRRTVNNWKPIKGQPLTELDKKILYIQNKGHLVPTRKLIKTPE
                     QIEGIRRSSVINTGVLDLIQKEIKEGMSTAVIDKLVYDYTVGHGAIPAPLNYEGFPKS
                     VCTSINEVVCHGIPSEKEILRDGDIINVDVSTILDGYYSDASRMFMIGNVSPKKQKLV
                     QVAKECLEIGIKAAKPFGFVGDIGNAIQKHAEKNGFSVVRDLCGHGVGLEFHEEPEVC
                     HFGRKGTGMLLVPGMVFTIEPMINMGTWKVFIDEEDGWTVITEDELPSAQWEHTFLMT
                     ETGLEILTY"
     gene            complement(2810..6370)
                     /gene="porW"
                     /locus_tag="ACZPB4_14715"
                     /gene_synonym="sprE"
     CDS             complement(2810..6370)
                     /gene="porW"
                     /locus_tag="ACZPB4_14715"
                     /gene_synonym="sprE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IX secretion system periplasmic lipoprotein
                     PorW/SprE"
                     /protein_id="HIR1099504.1"
                     /translation="MKKGFYYIVALLTVLLLWSCSTKKNTKASRFYHAFTTRYNIYFN
                     GKQAFDEALKSQQDGYKENYSDRIYMYPISAQPKDKAEPGGPFDRTIEKSNKAIKLHS
                     IKAKPAKKPGWRNNPKLRAIQEQEEYNPFLKNSWLIMGQAQFYNADFLQASATFSYIA
                     RHYAKDEEVVAEARLWQARCYSEMGWFYESEDILDKMNKNGIPASALKQYAAVYADYL
                     IKNGQFEDAIPYLKTAIKAEKNRKQRTRMKYLLGQIYADQELDGLAYKTFGEVARSNP
                     PYELEFASRIRQTEVFSGTNYLKVVKMLEKMAKSQKNKDYLDQVYYALGNVYLSREDT
                     VNAIKNYQLGIDKSTLNGMDKAICQIKLGDIYFTMRDYVKAQPCFSGALAGIQKEYKD
                     YERVSKLSAILDELVVHVEAVHLQDSLQALAKLPEAERLAIIDKKIEEVKKEEEEAKA
                     LAEKEAYLAEQEAKGTGIDRPGTETNVVVLPNASGGASFYFYNPQTVAQGKTQFQRKW
                     GRRPLEDHWRRRKKELSTFNENLDEEMLAEGDSTQMVGPDGEPLPTDSIGGDLPAVAA
                     DDPHTREYYLQQLPFTQEDIDASNIIIIDGLYNMAMIYKDKLEDIPLSVEAFENLERR
                     FPDNEHRLESYYQVYLMALKTGNTALATEYKNKLMNAFPESDYAVAVADPNYEYNIRM
                     MDVVQDSIYQATYDRYLESDTAYVRKSFRYVSEKYPLATLMPKFMFLDALSYVQAGDA
                     EGFKNALKALVEKYPNADVTELAGEMLKGVLRGRALVQGGVKGMSWNLRFGLGEDGML
                     SAEDSARVFNPERNTPYQMLLVYPTGSVDQNQLLFAVAAYNFANFMVKEFDLALEQAG
                     PISMLAIKGFISFDEIIQYYKMIYGKDGYATALNKAVAVLPISDDNYETLMRGKTLDE
                     YITFFDESFGEELPDLAGRWKARMEAAKEEEATEDEMITEEEAEVPEEADELKLEVEP
                     EKQPVTEPEEEQRPVQEPVRQPAIPVVPDTIEVPAFDKPEIQPVDTLRKDTVPVVQPA
                     VEDQGMTLKEIQEIRKREAAEEEARKEEARKAFEAQQKADKELREQKAKEQEELLKKQ
                     AEEERALLKAKADREKQLEADRKAKLKQAEADRKAKLKAREDLRKEKERAYKERLKQK
                     EKERKEKERLYKQKLKEKEKARKEALREKEKAAREKARKR"
     gene            complement(6378..7181)
                     /locus_tag="ACZPB4_14720"
     CDS             complement(6378..7181)
                     /locus_tag="ACZPB4_14720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HIR1099505.1"
                     /translation="MDLLQYAFFQNALIGSLLTAIACGIVGTYIVSRRLVFISGGITH
                     ASFGGLGLGFYLGTNPILMAMLFSILSAFGVEWASKTQNVREDSAIAGVWSLGMALGV
                     IFIFLTPGYAPNLSAYLFGNILTISTADILWILGLVVLLILIFSLFLREIVYVAFDRD
                     FAVTQGLPVKWIEYTMMCFIAMTIVLSIRLVGIMLLMSLLTLPQITVNLFTSDFKKIM
                     WGSIAIGFLGCVSGLVLSYFLNVPSGAFIILFLVVLFLALKAIKPLLRR"
     gene            complement(7199..7618)
                     /locus_tag="ACZPB4_14725"
     CDS             complement(7199..7618)
                     /locus_tag="ACZPB4_14725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase"
                     /protein_id="HIR1099506.1"
                     /translation="MWYIVISLIGLGVVAAIAGYFRNKKLQKMLERGEISEIPEAQEI
                     PEVCCGQHETCERDSLLAAVSKKIEYYNDEELDRFQGVEADAYDEEAVEEFSEVLYTL
                     REVEVAGWLRSLQLRGINLPDALKDEAFLIIGERRTH"
     gene            complement(7654..8889)
                     /locus_tag="ACZPB4_14730"
     CDS             complement(7654..8889)
                     /locus_tag="ACZPB4_14730"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HIR1099507.1"
                     /translation="MNYQIDAPGSAIRTTVKLPASKSISNRALILNALSYSAYDVENL
                     SDCDDTNLMVKALNSNDRDFNVGAAGTTMRFLTAFLSKVVGEWTITGTERMKNRPIKV
                     LVDALNALGARIEYMEKEGYPPLRIFGSALQGGEISLPGNVSSQYISAILMIAPLTEN
                     GVMLHLEGAIISRPYIHITLQLMEQYGVRASWTENTIKVLPQEYKPIRFTVESDWSAA
                     SYWYEIMALSKNAEIELLGLFKNSLQGDAAGAKLFAQLGVGTTYTKRGVVLKHTGNIC
                     EKLVYNFVNEPDLAQTFVVTCVLLNIPFRFTGLQSLKIKETDRIEALKTELRKLGYVL
                     TDRNDSILEWNGERREPESHPVIATYEDHRMALSFAPAALVRPEGIEIAHPQVVSKSY
                     PHYWEDLKAAGFSIRESAL"
     gene            complement(9521..10342)
                     /locus_tag="ACZPB4_14735"
     CDS             complement(9521..10342)
                     /locus_tag="ACZPB4_14735"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HIR1099508.1"
                     /translation="MNWMKKVAVALVCLLPLGLQAAKVDTLQVKSPSMNKSIEVVVVS
                     PDVAATKACPVIYLLHGYGGNARTWVGIKPDLSKIADEKGIFFVCPDGKNTWYWDSPL
                     NADVRYETFISDELVKYVDSHYKTVADRKGRAITGLSMGGHGAMWNGLRHSDVFSAAG
                     STSGGVDIRPFPKNWEMSVQIGEKAKYPENWEKYTVINLVPTLRKDQIALIFDCGDSD
                     FFLEVNKNYHEALLKQGIDHDFITRPGNHDSQYWNNSIDYQILFFWKHFLKMKAL"
BASE COUNT         2810 a         2633 c         2161 g         2810 t
ORIGIN      
        1 atcatgggat tacatctcga aggcaactat ttgaatatgg ctatgaaagg cggacaagac
       61 cctaattata tttacccgcc cgatccccaa gaatataagg aattactaaa cagtacccaa
      121 tgtattaaac gctggagcgc cgcccccgag cttgacgggg ctttggtatt cggtaaatat
      181 gcgtcagctc atggtgtgtt ggtttcacta gcccacacca cagccgatta tctccaagtg
      241 aaaaaagcat acgaagccgg attcacccat gctacccact tctacaatgc catgacttcc
      301 gtccataaag accgtgagta taaacatgaa ggaacggtag aaggtattta tctcatgaaa
      361 gatatgaccg ttgaagttgt agccgatggt atccacgtac caccagcaat cttaaagttg
      421 gtatatcaaa tcaaaggggt agaacgtacg tccttaatca cggacgcaat ggccgccgcc
      481 gcttgcgata acggtacgga acattttccg gactcccggg taattatcga ggaaggcgta
      541 tgtaaattag ccgatcgctc agctatcgca ggaagtatag ctaccggaat ccgcttgatc
      601 cgtaccttag tcgagaaagc ggaaattcca ttgcacgacg ctgttcgtat ggcttccgaa
      661 agcccagccc gcctaatggg tattttagac tgtaaaggaa cattggagaa aggaaaggat
      721 gccgatatca tcattttcaa caacgatata gagattcaag agaccttcat cgaaggtaaa
      781 cggctctcca aagaataaga aatccaataa acaatgactt ctcctatctt gtttttagat
      841 aaataagggc atgaatgtat atggaaaacg taaaagaaca ttactggaga tactcattga
      901 tcaccattat attaggacta ggggtaattc tattttttaa gattaccccg tttcttggag
      961 gtatacttgg agcattcacc atctatatat tgctgcgtgg acagatgttc cacctgacag
     1021 aaaagctaaa tatgagaccg gcttttgcag ctttactgtt actgggggaa acaatcttat
     1081 gtttcttaat cccaatcaca tcggcgatct ggttggtaat caacaaaact caaaatatta
     1141 atttagaccc gactgtactg ctaaatacag gccaacatat agcggatcta gttcaggaaa
     1201 agaccgggtt tgatgtactg gatagaggaa acttattaaa agcggcctct atactcccac
     1261 aaatcggaca gtttttagtg ggtagcataa gcagtttcgc cgtaaatgtc gtcgtcttga
     1321 ttttcattct gtacttcatg ctgataggcg gaagaaaaat ggaaaactat ctatacacct
     1381 tattcccctt cagtgatcaa aacaaggatg aggtactcaa cgagatcaat atgatcgtaa
     1441 aatcaaacgc cataggtatc cctcttttgg cggttataca aggtatcgta gcggtgatcg
     1501 gttactttat ctttcagact cccgatccgc tgttatttgg gtttctcact tgtatcgcta
     1561 cgatcattcc cattgtaggg accgcattgg tctgggttcc gttggcggct tatatggctt
     1621 taaacggaga ttgggtacat gccttgggat tggctattta tgccttgctt gtcattacga
     1681 acgtcgataa tctgattcgt tttatcctac aaaagaagtt ggcggatata catccgttaa
     1741 tcaccgtctt cggagtcgta atcgggttgt ccttattcgg atttatgggg atcatcttcg
     1801 ggccgttgtt agtatcctta ttccttcttt gtatagatat cttcaagaag agctatttgg
     1861 ataaataaag agtatctaca ggacagggta tcttaaaaag tcataccttt acactacatt
     1921 ttgagtaaaa cgaattaata tgtcacgtag aacagtaaac aattggaagc ctatcaaggg
     1981 gcaacctctc accgaattag acaagaaaat cctatatatc caaaataaag gacatttagt
     2041 acccacccgc aagcttatca agactccaga gcagattgag ggcatccgca gaagtagcgt
     2101 gatcaataca ggggtgctgg atttaatcca gaaggagatt aaagaaggta tgtctacagc
     2161 tgttatcgat aaattggtgt atgattatac ggtagggcat ggagcgattc cagccccctt
     2221 aaactatgag gggttcccta aaagtgtatg tacctctatc aacgaggtcg tttgtcacgg
     2281 tattcccagt gagaaggaga tcctaagaga cggtgacatt attaatgtgg atgtctcaac
     2341 gattttagat ggttattatt cggatgcgtc ccgcatgttc atgatcggga acgtatctcc
     2401 gaaaaagcag aaattggtac aggtcgccaa ggaatgtctg gagatcggta taaaagcggc
     2461 gaagccgttc ggattcgtcg gtgatatagg caacgctatt caaaagcatg cggagaaaaa
     2521 cggattctct gtcgtacggg atttatgcgg acatggcgtc ggtctggaat tccatgagga
     2581 accggaagtt tgtcatttcg gacggaaagg aactgggatg cttttagttc cgggtatggt
     2641 ctttacgatc gagcctatga ttaacatggg tacttggaaa gtatttatcg acgaggaaga
     2701 cggttggaca gtcatcaccg aggatgaact accctccgcc caatgggaac ataccttctt
     2761 gatgacagag acaggattgg aaattcttac ctattaatat ctaatgcaat taacgcttcc
     2821 gggccttttc ccgggcggcc ttttcctttt cccgcaaggc ttccttgcgg gctttttctt
     2881 tctctttcaa tttctgcttg tataagcgct ccttctcctt acgctctttt tccttctgtt
     2941 tcaggcgttc cttataagca cgttcctttt ccttacgaag gtcctcacga gctttcagtt
     3001 tcgccttacg gtcggcttcc gcttgtttca gcttggcctt gcgatcagct tccaactgtt
     3061 tctctcgatc agccttcgct ttcaacaggg cacgttcttc ctccgcttgc ttcttgagaa
     3121 gttcttcctg ttctttcgct ttctgctcac gtaattcctt atccgccttt tgctgggcct
     3181 cgaaagcctt acgagcctct tccttgcggg cttcttcttc ggcagcttcc cgtttacgga
     3241 tctcttggat ttctttcaag gtcatgcctt gatcctcaac cgccggctga acaacaggaa
     3301 ccgtatcctt acgaagggta tcgacaggct ggatttccgg tttgtcaaac gcagggacct
     3361 caatcgtatc cgggacgact ggtatagcgg gctgtcgaac aggttcttga acaggccgtt
     3421 gttcctcctc cggctctgta acaggttgtt tttccggttc aacttctagt ttcaattcat
     3481 ctgcctcttc cggaacttcg gcttcttcct ccgtgatcat ttcatcttca gtcgcctcct
     3541 cctccttagc ggcttccata cgggctttcc aacgacctgc cagatccggt aattcctcac
     3601 cgaagctctc atcgaagaag gtgatatatt catccaaggt cttgccacgc atcaaggtct
     3661 cataattatc atcagagatc ggtaacacgg caaccgcttt attcaaggcc gtagcatagc
     3721 catccttacc gtatatcatc ttataatatt ggataatctc gtcaaaacta ataaatcctt
     3781 taatcgccag catactgatc gggccggcct gctccaaagc caaatcaaac tcttttacca
     3841 tgaagttcgc gaagttataa gcggcgacag cgaatagcaa ctggttctga tctacgctac
     3901 ccgtaggata taccaaaagc atctgataag gcgtgttccg ttccggatta aatacacggg
     3961 ccgaatcctc ggcagatagc ataccatcct cgcccaaacc gaatcgtaag ttccaactca
     4021 tacctttcac acccccctgc accaaggcac gtccccgaag aacacctttc aacatctccc
     4081 cggccagttc cgtgacatcc gcgttcggat acttctcgac cagcgctttc aaggcattct
     4141 taaacccttc cgcatccccg gcctgcacat atgataacgc atccaagaac atgaatttag
     4201 gcatcaacgt agccaatgga tatttctcgc ttacgtaccg gaaactctta cgtacatacg
     4261 ctgtatcgct ctccagatag cggtcgtaag tagcttgata gatcgagtct tgtaccacat
     4321 ccatcatgcg gatattatac tcgtaattcg gatcagccac agctaccgca taatcgcttt
     4381 ccgggaaggc attcattagt ttattcttat actcggtagc caacgctgta tttccggttt
     4441 tcaaggccat caaatatact tgataatagc tctccaaacg gtgctcatta tccgggaaac
     4501 ggcgttccaa attctcgaac gcctcgacag ataaggggat atcctccaac ttatccttat
     4561 agatcatcgc catattgtaa agaccgtcta taataataat gttagaagcg tctatatcct
     4621 cttgcgtgaa aggtagctgc tgtagataat actcacgggt atgcggatca tcggcggcaa
     4681 cagccggcag atcaccgcct atcgaatcgg tcggcaacgg ctcaccgtcc ggccctacca
     4741 tttgggtgga atctccctcg gccagcatct cctcatccag attctcatta aaggtagaga
     4801 gttccttctt acggcggcgc cagtgatctt ccaacggacg acgtccccat ttacgctgga
     4861 actgtgtctt tccttgcgct acggtctgag ggttatagaa atagaaagac gctccaccgg
     4921 acgcgttcgg caagacaaca acgttggttt ccgtaccggg acggtcgatt ccggtgcctt
     4981 tcgcttcctg ctcggccaga taagcctcct tctcagccaa ggctttcgcc tcttcctctt
     5041 ctttctttac ctcctcaatc ttcttatcga taatcgctaa ccgctccgct tccggtaatt
     5101 tagccaaggc ttgcaaactg tcttgaagat ggaccgcttc tacatgcacg accaattcat
     5161 ccagaatcgc cgacaattta gaaacccgtt cataatcctt gtattccttt tgaattccgg
     5221 ctaaggctcc gctaaagcaa ggttgcgctt tcacgtaatc ccgcatcgta aaatagatat
     5281 ctcccagctt tatctggcag atcgccttat ccattccatt caatgtactc ttatcgatac
     5341 cgagttgata gttctttatg gcattcaccg tatcttcccg gctgaggtat acatttccta
     5401 aagcatagta tacttgatcc agataatcct tattcttttg gcttttcgcc attttctcga
     5461 gcatcttcac cactttcaag taattcgtac ccgagaatac ttctgtctga cggatacgtg
     5521 aggcaaattc caactcatac ggaggattcg aacgggctac ctcaccaaag gtcttataag
     5581 ccaagccatc taattcttga tccgcataga tttgtcccaa aagatacttc atccgggtac
     5641 gttgcttccg gtttttctcc gccttgatag cggtcttcag ataagggatg gcatcctcga
     5701 actgcccgtt cttgatcaaa taatcggcat acaccgccgc atattgcttc aaagcggaag
     5761 caggaatacc gttcttgttc atcttatcca agatatcctc ggattcatag aaccaaccca
     5821 tctcggaata acaacgggct tgccacaaac gggcctcggc cacgacctcc tcgtccttcg
     5881 cgtaatgacg agctatatag gaaaaggtag cggaggcttg caggaaatcg gcattgtaga
     5941 attgcgcctg tcccatgatc agccaactat tctttaagaa agggttatac tcctcttgtt
     6001 cttggatagc acgtagtttg ggattattcc gccagcccgg tttcttggcc ggtttcgctt
     6061 ttatggagtg tagtttaata gctttattac ttttctcgat cgtccggtcg aaagggccgc
     6121 ccggctcggc tttgtcttta ggctgggcgc taatcggata catatagatc ctgtcggaat
     6181 agttctcttt atatccgtcc tgttggcttt tcagtgcctc gtcaaaggct tgttttccat
     6241 tgaaataaat attataacgg gtcgtaaagg catgataaaa acggctcgct ttcgtgttct
     6301 tcttcgtgct gcacgaccaa agcaagagta ccgttaataa cgccactatg taataaaacc
     6361 cttttttcat tctttaatta acgccgtaac aacggtttta ttgctttcaa ggccaaaaag
     6421 aggaccacca aaaacaagat gataaacgca ccggaaggca cgttcaggaa ataagaaaga
     6481 accagtccgg agacgcaacc cagaaagccg atcgcgatac ttccccacat gatcttcttg
     6541 aagtcggaag taaacaggtt caccgttatt tgaggcaagg tcagcaaact catcaatagc
     6601 ataatcccta ccaaacggat cgaaagaaca attgtcatgg cgataaagca catcatcgta
     6661 tactcgatcc attttaccgg taggccttgc gtgacagcga agtcacgatc gaatgccacg
     6721 taaacaatct cacggaggaa aagggagaat atgagtatca acaataccac caaccctaaa
     6781 atccataaga tatcggccgt agagatcgtt aatatattac caaatagata ggcggataga
     6841 ttcggggcgt accccggggt aagaaagatg aagatcactc ccaaagccat acccagcgac
     6901 catacgcccg ctatggcgga atcctccctt acgttttgtg tcttgctcgc ccactccacg
     6961 ccaaaagcag agaggatcga aaacaacatc gccatcaaga tcgggtttgt tcccagataa
     7021 aaacccaagc ccaaaccacc gaacgaagca tgcgtgatcc ctccgctgat aaataccaac
     7081 cggcgggata cgatgtaagt cccgacaatc ccacaagcga tggcggttag caagctcccg
     7141 atcaaggcat tctgaaaaaa ggcatattgc aataaatcca tatgattcgt ttcctaaatt
     7201 aatgagtacg gcgttcgcca atgatcaaga atgcctcatc cttcaaggca tccggcaaat
     7261 tgatcccccg caattgcagg ctacggagcc aaccggccac ctccacttcc cggagggtat
     7321 aaagcacttc actaaactcc tcaacggctt cctcatcgta agcgtccgct tccactcctt
     7381 ggaaccgatc cagttcctca tcgttataat attcgatttt cttgctgacg gcggctaata
     7441 aactatcccg ctcgcaagtc tcatgttgtc cgcagcaaac ctccggaatc tcctgtgcct
     7501 cggggatctc cgagatctcc ccccgttcca gcatcttctg aagtttctta ttccggaaat
     7561 acccggcgat agcggctacg acacccagac ctataagact tatgacaatg taccacataa
     7621 ttcaattgaa agttgagaat tgaaaactga aaattaaagg gctgattccc taatagagaa
     7681 accagcggcc ttaagatctt cccaataatg gggataactc ttgctgacca cttgcgggtg
     7741 ggcgatctct atcccctcgg gacgtaccaa agcggcggga gcgaatgaca aagccatccg
     7801 atgatcctcg taagtggcga ttaccggatg cgactccggt tccctgcgtt caccgttcca
     7861 ctccaagatg ctatcattgc gatccgtcaa cacataacct aatttacgaa gctctgtctt
     7921 caatgcctcg atccgatccg tctccttgat cttcaatgat tgaagtcccg taaagcggaa
     7981 agggatattt aataacacgc aagtcaccac aaaggtttga gccaaatccg gttcattcac
     8041 gaagttataa accaacttct cacagatatt tccagtatgc tttaacacga ctccacgttt
     8101 cgtataagta gtgcccactc ccaattgagc gaacaacttc gctccggcgg catctccctg
     8161 caagctattc ttgaataaac ctaacaattc gatctcagca tttttcgata acgccatgat
     8221 ctcataccaa taagaagcgg cactccaatc ggattccacc gtaaaacgaa tcggcttata
     8281 ctcttgggga agtactttga tcgtattctc cgtccaagag gctctcactc catattgctc
     8341 catcaattgc aaggtgatat ggatataggg cctagagata atagcgccct ccaaatgcaa
     8401 cataacccca ttttctgtta acggggcgat catcaagata gcggatatat attgagagct
     8461 aacatttccc ggtagcgaga tctctccgcc ttgcaaggcg cttccgaaaa tacgcaaagg
     8521 aggataaccc tccttctcca tgtactcgat ccgggcgcct aaagcgttca gcgcatccac
     8581 caacaccttg atcggacggt tcttcatgcg ttcggttccc gtaatcgtcc attcgcccac
     8641 caccttcgag aggaaagcag taaggaaacg catcgtcgta cccgccgcac ccacattaaa
     8701 atcccgatcg ttcgagttca atgcctttac catcaaattt gtatcatcgc aatcggataa
     8761 gttctccaca tcgtatgcgc tataacttag cgcattcaag atcaatgccc tgttactgat
     8821 acttttagaa gcgggaagct ttacggtagt ccggatagcg gaacccggag catctatctg
     8881 ataattcatc gctttcgtat attcaagatt caagaggcaa aagtacgaaa attagcgtac
     8941 atattggagt ataacagcgg gaaactttct tctttcctct cactacatga ctccttacat
     9001 taacaacgga cccctttgcc gacatgatac agaaaccggc cttcggcttt ctttatgctt
     9061 cttctcgaac accaatcgtg acaaggcgtt cgtttaaacc gatccaacca gtagacggga
     9121 ggggcaataa aacgcccttt taagtgagaa tattcccgtt ttcaggcacg aaaggcgatg
     9181 aaagcctaca tgtatagtcg cattgggcaa cgccaatact gccgttgggc attataaaca
     9241 gtcacgaata gggttgtcag tagtcgtgaa taggcatcgt aacccggtta gaacccagtc
     9301 gtaaccctat cggatagccc gaagaagtca atggatatga attaggatga attattttcg
     9361 ctagaatgaa aggcggtttt tcggtattgt attatcaatg aacgaattat tgtttttttc
     9421 ttgcgtatta ggcaacgagt cgtacatagt cccggaaaaa tcggttctcc gggacttcag
     9481 tttacaaaat gtcagaatgt caaatcgcca aacggtctta tcacaaggcc ttcatcttca
     9541 ggaaatgctt ccagaaaaag aggatctggt aatcaataga attattccag tattgtgaat
     9601 catgattacc cgggcgagtg ataaagtcgt ggtcgatgcc ttgttttaat aacgcctcgt
     9661 ggtagttctt attcacctcc aaaaagaaat cgctgtcacc gcaatcgaag atcaaagcga
     9721 tctggtcttt cctcaaggtt ggaaccaaat tgataaccgt gtacttctcc cagttttccg
     9781 gatatttcgc cttctcacct atttgcacgc tcatctccca gtttttcggg aaagggcgga
     9841 tatccacgcc accgctagta cttcccgcag cggagaaaac atcgctatga cgaaggccat
     9901 tccacatagc gccatgtcca cccatgctca agccggtaat agcacgtccc ttacgatcgg
     9961 ccacggtctt ataatgggaa tccacgtatt tcaccaactc atccgagatg aaagtctcat
    10021 accgtacatc agcgttcaaa gggctatccc aataccacgt attcttacca tccgggcata
    10081 cgaaaaagat acccttctca tcagcgatct tagatagatc cggcttgata ccgacccatg
    10141 tacgagcgtt accgccatag ccatgcaaca aataaatcac cggacacgct ttcgtcgcgg
    10201 caacatccgg acttaccacg actacctcta tacttttatt catcgaagga cttttcactt
    10261 gcaaagtatc taccttcgcc gcctgcaaac caagcggaag caaacaaacc aacgctaccg
    10321 ctaccttttt catccaattc atatcagtga acattaatga ttaattcccc gtagccttgt
    10381 tttcaaggaa ctacggggac aaatatacag attt
//
LOCUS       DBMDTB010000120        10333 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_1884_length_10333_cov_9.145817, whole genome shotgun sequence.
ACCESSION   DBMDTB010000120 DBMDTB010000000
VERSION     DBMDTB010000120.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 10333)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 10333)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10333
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1884_length_10333_cov_9.145817"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..1116)
                     /locus_tag="ACZPB4_14740"
     CDS             complement(<1..1116)
                     /locus_tag="ACZPB4_14740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016209 - antioxidant activity [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin domain-containing protein"
                     /protein_id="HIR1099509.1"
                     /translation="MKKYLILAASALLLAACSEKPGYEINGTVANTDLNGKYVYLYEY
                     GVQDAAPMDSALVQNGTFTFKGTQDAPALRKLAFAEDVVEPKRAASGENAPFTSIFVL
                     ENGKLQAILDEAASAVSGTPENDGLKALQAQMKTLRADLEKLSADMKSEDKEVVSAAE
                     KKYDEIDQKVTDAVKTYILNNTTKQSAAKLLYDFRYSLDEAAQNEIIAKADSAFKAVP
                     NIDKLMAHLDVLKTVAVGKKFVDFEMADPNGKTHKLSEFVGNGKNIVLIDFWASWCPP
                     CRRDMPNLVAAYKKYKNKGFEIVGISLDSKADAWAKGVKDLNITWPQLSDLQGWKNSG
                     AQLYGVNSIPHTVLVDKDGTIIAKNLHGEEIDAKLQEI"
     gene            complement(1265..4270)
                     /locus_tag="ACZPB4_14745"
     CDS             complement(1265..4270)
                     /locus_tag="ACZPB4_14745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M26 family metallopeptidase"
                     /protein_id="HIR1099510.1"
                     /translation="MKTYTKTIWNICACMLIILLGGCADDDIIRNDCGSTLQETESHL
                     ISTFSLPEGKTPIQDTREQIFFQLRSLSDNSIQLMEGKIRKNAGILSCEMFIPNNLVL
                     EDGDYILWLKFDEEGSVYPLSYHLTFRDKMVSMVRDTKYIYEMLNGEGTEENPYLITS
                     TNDFAYLVSQLATYDSNYGYGQFFKQIADIKAPIPNCLYQGNAYKSAPFAGNYDGDSH
                     KILNLTYLGTNGGEQSDAIGLFSILHDGAVIRNLDIEGADIEYPGNCCGLLAGVANGN
                     IRIENITLNGNIKSTKDKVGGLIGYIEGNAQSLAQISIRNVRLGVSFSESGSSYIGAL
                     IGWAENASIQVEDISSDGIFKNLRGNNHVAGLIGKLYGQIDARKIKLQHTTLNDFPIS
                     GNQNVGGLIGEAFLQAASNFKDITIDMPIKGSSYVGGLIGQIRSETPTNILIAIENFQ
                     LSNPANRSQIQGGSYVGGMIGYSHKTHANAFTIELKGESLFHASITGQSVIGGIFGSL
                     DDTQIQFTPASRLYMDNESLEASSGICGTLAGALSYQEPGKEILLDPEILVINPNIKI
                     KGGNNVGGIIGKLYNGTLTGTYTPEFSTTNVIVSKIPRPIFPGNINSEKPYRENAASI
                     GGIVGYADKSTLRRLFTQPSIYGRSTVGGIIGYASDTQISDCGVKTETFNNGNNSAIM
                     VGGIIGQASCSSHCEFSNLVNYSNISSGSNYIGGIFGSMVAGTSVKINKVVNLGKISA
                     TNNVGGIIGKTSGKDIEVYDAANFGVIQGIAGDKECGVGGIAGAAEDAITIYKSVNHG
                     NITINRNAKYYGAGGILGYVKQGGAHVRYCCNRANIDYPKDKEDSHGIGGIVGSIEKA
                     NDNDDSYVLDCYNMGEINGQQKATSTLGTDYRGGIVGNLGSHGRCYRAVNGGYVRFGN
                     AGVGYGNKKNLTHIYISPGTGKDFGATSIPLPIREDKNIYQGFDFTGDHDPNRQPVWV
                     LGGTYSSENKMLPYLHSGKCYFQFAKYAP"
     gene            complement(4289..7192)
                     /locus_tag="ACZPB4_14750"
     CDS             complement(4289..7192)
                     /locus_tag="ACZPB4_14750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
                     /protein_id="HIR1099511.1"
                     /translation="MKTNYFFLLFFLLILMGCSDDKNIPDIPASTEDTYEGVHDLISF
                     TKETEDFTYGDLTFHIKTPDGNIIQRKAKHRRLSGTSLFTMEKGLKEGKYQLLYMEYT
                     IQSDCPDIDGRNGEFGMGCYITVSENGISTETNRDERIGLYGNGTPEDPYRITSADDL
                     AKIQEAILNFHNNGNLVNSYTCFEQQNDISMANYNDQCGWEGNWYQIGLSASYPFTGY
                     YDGNGYTIRDLKMLDKNAVGASLFGFVNQAIISNLTIEKATITGYGALSAIVGAVTTK
                     GGSINKTFIKGCVVKKSTIESRSDGVVTDGMAIGGIAGMVDPNVNLWIDSCSVEDCTI
                     NGAIAVGGILGGGTVYSMTQITNSHNRNTKVTASYNCAGGIVGYADTLYVYSCSNNGT
                     IKGAASTTAPPGNLPANSIYNVGTGGIAGGSGLSTIISSRNSGTVQGSRGVGGIIGST
                     LVTTQPRTYYNNTFIGFCSNSGNINGDSYIGGLCGEAQLGAYKSYNEGMIEANSSFAG
                     GILGFAPLASITNTANFNKVIASSYSGGIAGSILAGSLGINTNLGEVASYHEYAGGMI
                     GRAGNTLAMNYCSNFAPISGSSYLGGMIGEVGDAKKWTIMDGVSLGFATFELASTLVG
                     FVPFAKIVGESGEILVNCALTVLSLVLNDIDILSEGFSVFGLISHGHPEIIETERLKG
                     VITHDIAMLESDMDTKLANKIDNLSFASIKLRSKDMTNRFMSNRKALTEWFECGANHQ
                     IYSDAMNYKRGLLSKQILKSKKNEEVLHTVVSGVCCAVNSALLFVTVITFPEGVPAVA
                     LMGGALALVSFGNSVSATLDDFVENSVVITQCLNAGEIGQYSSGGLVGQLQQSCLISD
                     CINMGRSNKRANALIGVVNPNVRVGRNLNVGENWYLFAPPASVSYFGNYCMLGTVEQP
                     NPVIMNIFCLQDLKSEKTFTGWDFDVKWEIPSNETGSFPIPKKSEMQFDKPNL"
     gene            complement(7312..9021)
                     /locus_tag="ACZPB4_14755"
     CDS             complement(7312..9021)
                     /locus_tag="ACZPB4_14755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIR1099512.1"
                     /translation="MRKSPLALLLSLICLFSSHNEIQAQGHPPTDSLRQRAAASVGKE
                     KHDLLMRIAMSTNDIADWDATLNDAIDRCDTPAICRSRLNRIQCLFNFYSVDSAIIEA
                     RESLPFILNAKQYSFYFSTYNTYISGLFKQRRFDEAREEATAMFETAQQVKQPVGMTM
                     ALQVQGSMYYKLGLYDQALTSQEKGIAICPTYENGENQVLYISAVLYEWLFMTALKVN
                     DTERISRYADSYAALVKWRDEHGKVDPTGHYPVTSRSLQAFSFLKKGQIKEERRLLDE
                     AARFIHPQIPANAYEHFYEARRELRKMTGDYQGAIKDMDILLTAHEGDLSFYMDDLLK
                     KAELLAHSGDPRSCISLYHTYIQVKDSVNRLDIASRMDQLRTIYEVDRLNQERQYARN
                     WMFAAFTGCLLLVLLLAGYIIYSQCLKAKNQVLYRRIQEQIRQENKAVETIKQIPEND
                     LSRELRLFINLNELLEKEKLYTDPTLNRDDLAQRLGTNRTYLMEAVRTYSGNMTVREY
                     IYDFRLKHAAELLSSPSALSIDQICYDSGFASRSVFYRLFRQSYGLSPNEYRKLAEKE
                     KEN"
     gene            9573..>10333
                     /locus_tag="ACZPB4_14760"
     CDS             9573..>10333
                     /locus_tag="ACZPB4_14760"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009123978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HIR1099513.1"
                     /translation="MTKSALQIARAAYQPKVPAALKGAVKAVDGEYTQSVADQEEIKK
                     LFPNTYGMPIVTFEKSNEEKAMPVMNVGVILSGGQAPGGHNVIAGLFDGIKAHNADSR
                     LYGFILGPGGLIDHKYMELTADIIDEYRNTGGFDMIGSGRTKLETKEQFDKGLQILKE
                     LDIKALVIIGGDDSNTNACVLAEYYKAIGAGVQVIGCPKTIDGDLKNAQIETSFGFDT
                     ACKVYSEVIGNIQRDCNSAQKYWHFIKLMGRSASH"
BASE COUNT         2516 a         2389 c         2370 g         3058 t
ORIGIN      
        1 tatttcttga agtttagcgt cgatctcctc gccatgtagg ttcttggcga tgatcgttcc
       61 gtccttatcc accaatacgg tgtgagggat gctgtttacc ccgtatagtt gggcaccgga
      121 gtttttccag ccttgcaagt cggagagttg gggccatgtg atatttaggt cctttacgcc
      181 tttcgcccat gcgtctgcct tgctatccaa ggagatgcca acgatctcga aacctttgtt
      241 cttgtatttc ttgtaagcgg ctaccaaatt cggcatatcc cggcggcaag gagggcacca
      301 acttgcccag aaatcgatca atacgatgtt cttgccatta ccaacgaatt cggatagctt
      361 gtgcgtctta ccgttcgggt cggccatctc gaagtccacg aacttcttgc ctacggctac
      421 ggttttcagt acatctaggt gagccatgag cttatcgatg ttcggaacgg ccttgaaagc
      481 ggagtccgcc ttggcgataa tctcgttctg ggccgcctcg tccaagctat aacggaaatc
      541 gtataataac ttggcggcgg attgcttggt cgtattattc aatatgtaag tcttgacggc
      601 atcggttacc ttttggtcga tctcgtcata tttcttctcg gcggcgctta cgacttcctt
      661 atcctctgat ttcatgtcgg cggaaagctt ctccagatcc gcacgcaaag tcttcatttg
      721 tgcttgcagg gctttcaatc cgtcattctc cggtgttcca gaaacggcgg aagctgcctc
      781 atcaagaata gcctgtaatt taccattttc caatacgaat atgcttgtga aaggggcatt
      841 ctcgccggaa gcggcacgtt tgggttccac gacatcctcg gcgaaggcga gtttgcgtag
      901 ggcaggggca tcctgtgttc ctttgaacgt gaacgtaccg ttttgcacca atgcgctatc
      961 cattggggcg gcgtcttgta cgccatattc atacaggtaa acgtattttc cgtttagatc
     1021 ggtgttcgct acggtaccgt tgatctcgta acccggtttt tcgctgcatg cggctaggag
     1081 cagggctgat gcggcaagaa taagatactt tttcattttg tatttgtgtt atgtaagtaa
     1141 tgtattaaaa tatggaatat tgacttcgcg aatatacgaa gtcttttgtg aaaaccggac
     1201 gcaaaccgat gaatagttcg cgcccggtat ggatatatat agagtgtatt aaagagggtg
     1261 tattttatgg ggcatatttt gcgaattgga aataacattt tcctgaatgc aagtagggta
     1321 gcattttatt ctccgagcta tatgtgccac ccagaaccca gaccggttgc cggtttggat
     1381 catgatctcc cgtgaagtcg aatccttggt aaatattttt atcttctctg attggtagag
     1441 ggatagacgt tgccccaaag tctttgcctg taccgggcga gatatagata tgtgtcaggt
     1501 tcttcttgtt gccgtatccg acacctgcgt ttccaaagcg gacataaccc ccgttcacgg
     1561 cccggtaaca tctcccgtgg cttccgaggt ttcctacgat ccctccccgg tagtcggtac
     1621 caagcgtgct ggtcgctttt tgctgtccgt tgatttctcc catattgtag caatccagta
     1681 cgtaactgtc gtcgttatcg ttagcctttt ctatgctacc cacgatacct ccaatgccat
     1741 ggctgtcttc tttatctttc ggatagtcta tatttgcccg gttacagcag taacggacat
     1801 gtgctccccc ttgcttcaca taccccaaga tacctcctgc tccataatac ttggcattcc
     1861 tgtttatggt gatatttccg tggttaacgg atttataaat tgtaatggca tcctcggcgg
     1921 caccggctat accgcccact ccgcattctt tatctcctgc gataccttgg attacgccga
     1981 aattagctgc gtcataaacc tctatgtctt ttcctgaagt tttccctatg ataccgccta
     2041 cgttatttgt ggctgatatc ttacctaaat tcacgacttt attgatcttt acgctagttc
     2101 ccgctaccat actcccgaaa atgcctccga tataattgga tcctgaggag atattactgt
     2161 aatttactag attggaaaac tcacagtggg atgagcacga tgcttgtccg ataattcctc
     2221 ctaccataat ggcgctatta ttcccattat taaatgtttc tgttttcacg ccgcaatctg
     2281 atatttgagt atcgctcgca tatccgatga ttcctccgac tgtacttctg ccgtaaatgg
     2341 aaggttgcgt gaagagtctt ctgagagtag atttatcggc atatccgaca attcctccaa
     2401 tagaagcggc attttctcga tagggttttt ccgaatttat gttacccggg aaaataggtc
     2461 gtggaatctt gctcacgatt acgttcgtgg tactgaattc gggggtatag gttcctgtca
     2521 acgtcccatt atataatttt ccgatgattc ctcctacgtt atttcctcct tttattttga
     2581 tgttgggatt aatcaccaat atttccggat ccaaaagaat ttctttcccc ggttcttggt
     2641 aagataaggc tccggctaaa gtgccacaaa tccctgaaga agcttcaagg gattcattat
     2701 ccatatacaa tcgtgaggcc ggggtaaatt gtatttgggt atcatctaaa gaaccgaaaa
     2761 tacctcctat aacagactgc ccggttatcg aggcatgaaa caaggattcc cctttaagct
     2821 ctatcgtaaa tgcgttagcg tgtgttttgt gggaatatcc gatcattcca cccacataac
     2881 tacccccttg gatttgagac cgatttgccg gattggacaa ctggaagttc tcgatggcga
     2941 tgaggatatt ggtaggggtt tccgaccgga tctgaccgat caatccgccg acataggagc
     3001 tacctttgat cggcatgtcg atggttatgt ctttgaaatt ggatgccgcc tgtaagaatg
     3061 cctcaccgat caatccgcct acgttctggt ttccggatat cgggaaatcg tttaaggtgg
     3121 tatgttgcag cttaattttt ctggcatcga tttgaccata taatttcccg atcagaccgg
     3181 ccacatgatt attccctctc aagtttttga aaatcccgtc gctactgata tcctccactt
     3241 gaatggaagc gttctcggcc cagccgatca acgctccgat ataagagctg ccggattccg
     3301 agaatgagac gcccaatcgc acattccgga tactgatttg tgccaacgac tgggcgttgc
     3361 cctcgatata gcctattaaa ccgccaacct tatccttcgt ggacttgata ttcccgttta
     3421 aggttatatt ctcgattcgt atatttccgt tagctactcc cgcaagcaat ccgcaacaat
     3481 tccccggata ctctatatcc gctccttcta tatcaagatt ccggatcact gccccgtcgt
     3541 gtaaaatgga gaaaagcccg attgcgtcgc tttgctctcc gccgttcgtc ccgagatagg
     3601 ttaggtttag tatcttatgg gaatcaccgt cgtagtttcc cgcgaacggg gcgcttttat
     3661 aagcgttgcc ttgatacagg caattgggga taggagcttt gatgtcggct atttgcttga
     3721 agaattgccc gtatccgtaa ttactgtcgt acgtggctaa ttgagacacg agataggcga
     3781 aatcgttggt ggaagtaatc agataaggat tttcttccgt accttcgcca ttcagcatct
     3841 cgtaaatata tttagtatca cgtaccatac tgaccatctt gtcacggaat gtcagatgat
     3901 agcttagtgg atagacgctg ccttcttcat cgaattttaa ccaaagtata tagtctccat
     3961 cttctaatac cagattattg gggataaaca tttcacagga aagaatcccc gcgtttttcc
     4021 ggatcttacc ttccatgagc tgtatggagt tatcgctcag cgatctcaac tggaaaaaga
     4081 tctgttctct cgtatcttgt atgggagttt tgccttccgg caaggagaac gtgcttatta
     4141 gatgagattc tgtctcttgc aaggtcgatc cgcagtcgtt tcgtatgatg tcatcgtccg
     4201 cgcatccgcc gagcaagatg ataagcatgc atgcgcatat attccatatt gttttagtgt
     4261 atgttttcat gtttgtttgt tcgtttattt ataaattagg tttatcaaat tgcatctcgg
     4321 atttcttagg gatcggaaag ctacctgttt cgttggatgg tatttcccat tttacatcaa
     4381 agtcccatcc agtaaaggtc ttttccgact ttaagtcttg taagcagaat atgttcataa
     4441 tcacaggatt cggttgctct acagtgccca gcatacagta attcccaaaa taagaaacgg
     4501 atgcgggagg tgcgaaaaga taccaattct ccccgacatt caagttcctg cctaccctta
     4561 cgtttggatt gacaactcca attagggcat tggctctttt atttgagcgt cccatattta
     4621 tacaatcgga gataaggcag ctttgctgaa gttggcctac caagcctccg ctgctatatt
     4681 ggccaatctc tccggcgttc aagcattgtg tgataacgac ggagttttcc acgaaatcat
     4741 caagagtggc cgaaaccgaa ttgccgaaac tgactaacgc tagcgcacct cccatcaagg
     4801 ctacagcggg aacaccttcg gggaaagtga taactgtaac aaaaagcaag gctgaattga
     4861 ccgcgcaaca aacaccactg acaaccgtat gtagaacttc ttcgtttttt ttgcttttaa
     4921 ggatctgttt ggagagcaac cctctcttat aattcatcgc atcactataa atctggtggt
     4981 ttgccccaca ttcaaaccat tctgttaatg cctttcgatt agacatgaac ctatttgtca
     5041 tatctttgct cctcagtttg atgcttgcga acgataggtt atctatttta ttggccagtt
     5101 tcgtgtccat gtctgattcc aacatggcga tatcatgggt aatgacacct ttcagcctct
     5161 ctgtttctat aatctccgga tgaccgtgtg aaataagccc gaatacgcta aaaccttctg
     5221 ataaaatatc gatatcattt aagacgaggc taagtactgt aagggcgcag ttaacaagga
     5281 tttctccgct ttctcccacg attttagcga aagggacaaa tccgacaaga gtagacgcca
     5341 gctcgaatgt ggcaaacccc aaggatacgc catccatgat cgtccatttc tttgcgtcgc
     5401 ctacctcgcc gatcatacca ccgaggtatg aggagcctga tatcggcgcg aaattggaac
     5461 aatagttcat ggcaagcgta ttccctgccc ttcctatcat accaccggca tattcatggt
     5521 aggaggctac ttcccctaga ttcgtgttaa tacccaacga gccggcaagg atggaaccgg
     5581 ctattcctcc gctataagag gaggcgatta ctttattgaa attcgccgtg ttggtgatgg
     5641 aggccaaggg agcgaatcct aaaattccac cagcgaagga tgaattagcc tcgatcatac
     5701 cttcattata cgatttataa gcgccaagtt gcgcctcacc gcataatcct cctatataac
     5761 tgtcgccgtt tatattcccc gagttcgagc aaaaaccgat aaacgtgtta ttataataag
     5821 ttctcggctg ggtagttacc agtgtgcttc cgataattcc ccctacgccc ctgcttcctt
     5881 gcaccgtccc gctgtttcgg ctggaaatga tggtgctcaa tccgcttcct ccggcgatcc
     5941 cgcccgttcc tacattatat atagaattgg caggaaggtt tccgggagga gcggttgtgg
     6001 atgcggcacc tttgatagtg ccattattgc tgcatgaata tacatagagc gtatcggcgt
     6061 acccaacgat tcctccggca caattgtaag atgcggttac cttggtattc cggttgtggg
     6121 agttcgtgat ttgtgtcatt gagtacactg ttcctccgcc aaggattcct cctacggcaa
     6181 tcgccccgtt tatagtgcaa tcctctaccg agcaggaatc tatccagaga tttacgttcg
     6241 ggtctaccat gccggcgatc ccgcctatgg ccatgccgtc cgtgactacg ccatcgctac
     6301 ggctttcgat ggtggatttt tttactacgc acccttttat aaatgtctta ttgatgcttc
     6361 cccccttggt ggtaacggct cctacgatag ccgatagcgc tccatagccg gttatggtgg
     6421 ctttctcgat ggtgagattc gagatgatgg cttgatttac gaagccgaac aaactagcgc
     6481 ccacggcgtt tttatctaac attttcaaat cccggatcgt atagccgttg ccgtcataat
     6541 agcccgtgaa aggataactg gctgataatc cgatctggta ccagttgccc tcccagccgc
     6601 attggtcatt atagttggcc atgctaatgt cattttgttg ttcgaagcag gtgtaggaat
     6661 taacaaggtt accattgttg tggaagttga ggatcgcttc ttgtatcttc gccaaatcat
     6721 cggcagaggt tatccggtac ggatcttccg gcgtaccgtt cccatacagg ccgattcgct
     6781 cgtcacggtt ggtttcggtg gagatcccat tctcactgac ggtaatgtag caccccatgc
     6841 cgaactcccc attccgcccg tcaatgtccg ggcaatccga ttggatggta tattccatat
     6901 atagtagctg gtatttaccc tccttcagcc ctttttccat agtgaatagg gaagtcccgg
     6961 ataatcgccg gtgcttggct ttccgttgga taatgttccc gtcgggagtc ttgatgtgga
     7021 aagtcaggtc tccatacgtg aaatcttcgg tttctttcgt gaaactgatc agatcgtgta
     7081 ctccttcata ggtgtcctct gtggaggccg ggatatccgg aatgtttttg tcatccgaac
     7141 atcccatcag aatcaaaaga aagaaaagga gaaaaaaata atttgtcttc atatatagct
     7201 tgtttttagg attaacagat atcgtttcaa tatgcgaata gtaatcctaa aagctgtccg
     7261 tgtggcgcaa aacatttgtc cgtgtggcgc aagtttttga aatatagtat tttaattttc
     7321 tttttctttc tccgcaagtt ttcgatattc gttaggagac aggccatagc tctgtcggaa
     7381 aaggcggtaa aataccgagc gggaagcgaa cccggagtca tagcatattt gatcgatcga
     7441 gagggcggag ggagaggaga gcagttcggc ggcatgcttt agacgaaagt cataaatata
     7501 ttcgcggacg gtcatattcc cgctgtaagt acgtacggct tccatcaagt aggtacggtt
     7561 ggtccccaaa cgttgtgcca gatcatcccg gttcaaggtg ggatcggtgt atagcttttc
     7621 tttttccaat aactcgttca agtttatgaa taaacgtaat tcccgggaaa gatcgttctc
     7681 gggtatttgc ttaatggttt ccaccgcctt attctcctgc cggatctgtt cctgtatacg
     7741 tctgtaaagc acttgattct ttgcttttag acattgggaa taaatgatat atcccgctag
     7801 caaaaggaca aggagcaagc aaccggtaaa ggcggcgaac atccagttcc ttgcgtattg
     7861 cctctcttgg ttgagccggt ctacctcgta aatagtccgt agttgatcca tccgagaggc
     7921 gatatccaac cggtttaccg agtctttcac ctgtatatac gtatgataga gcgatataca
     7981 ggaccgggga tctccggaat gagccagaag ttccgctttc ttcaacaaat cgtccatata
     8041 gaaagatagg tcaccctcat gagcagttaa caggatatcc atatccttga tagccccttg
     8101 gtaatctcct gtcattttcc gtaattctcg acgagcctcg taaaaatgct cataagcgtt
     8161 ggccgggatc tggggatgaa taaaccgggc tgcctcatcc aacaatcgtc tctcctcttt
     8221 tatttgccct ttctttagga aagagaaggc ttggagagag cgggaggtga caggataatg
     8281 tccggtagga tctactttcc catgctcgtc cctccatttg acgagggcgg catagctgtc
     8341 ggcgtaacgg gatatgcgtt ccgtgtcgtt taccttcagg gcggtcatga agagccattc
     8401 gtaaagaacg gccgagatgt agagtacttg gttctcgcca ttctcgtagg tggggcatat
     8461 agcgatccct ttttcctgcg aggtgagggc ttggtcgtac aagccgagtt tataatacat
     8521 gctgccttgt acctgcaagg ccatcgtcat gcctaccggt tgtttaacct gttgcgccgt
     8581 ctcgaacatg gctgtggctt cctcacgggc ctcgtcgaac cgtctttgct tgaacaatcc
     8641 ggatatataa gtattatagg tggagaagta gaaactgtat tgcttggcat tcaatataaa
     8701 aggaaggctc tctcgtgcct cgatgatagc cgaatccacg gagtagaaat taaagaggca
     8761 ttgtatgcga ttcagccttg atcggcagat ggccggggtg tcgcaccggt cgatagcgtc
     8821 gttgagcgta gcgtcccagt cggcgatatc gttggtggac atggctatac gcatcagtag
     8881 atcatgcttt tccttaccca cgctcgctgc ggcccgttgt cgcaatgaat ctgtcggggg
     8941 atgtccttgc gcttgtatct cgttatgaga cgagaacagg cagataagcg ataataggag
     9001 tgcaagaggg ctttttcgca tcgaattttg tgattaacta acgttaatag aaggtgtaaa
     9061 tatacgaagt cttttgtgat aattaggtgc aagttgatga atagtttact ctattgtgcc
     9121 attgaagtag cctacagagt aaacggatta aaaaaataca ataaagcatt tgtttgaaat
     9181 ggtttataac tggcttataa ttagatggat ataaattatg atggagattt gagtaaaaca
     9241 cgtacatgtt ttcgaaaaaa cacgaccgtg tttcttgaaa attacgtacg tgtttttgga
     9301 aaaacacgac cgtgtaaaaa atagtcaagt aaaatataca gtaagctacc tgttttctcg
     9361 tgttcacttc atggtgacac accctcttct tgttgaaggt tgatcggtta taatgatgag
     9421 ggcaagttta ccagtgattt cccggaagtt tttttcgatg ctattttgaa tgaacatatc
     9481 ccccttctct tttattaata cggatttttt tccttatatt cgcgtcactt ttgaacacgt
     9541 atcaaataat ttctaaataa atcaattaag aaatgacaaa gagtgcatta caaatcgcaa
     9601 gagcagctta ccaaccgaag gtacccgctg cgttgaaagg tgcagtgaaa gccgttgacg
     9661 gcgagtatac tcaatcagta gccgatcagg aagaaatcaa gaaattgttc ccgaacactt
     9721 acggaatgcc gatcgttaca ttcgagaaga gtaacgagga gaaggctatg cctgtcatga
     9781 acgttggtgt gatcctttcc ggtggtcagg ctcccggtgg tcacaacgtg atcgctggtt
     9841 tgttcgatgg tatcaaggct cacaacgcag attctcgtct gtatggtttc atcttgggcc
     9901 cgggcggttt gatcgatcat aaatatatgg aattgacggc tgatattatc gacgagtacc
     9961 gtaacacggg tggtttcgat atgatcggtt ccggacgtac gaaattagag acgaaagagc
    10021 aattcgataa aggtcttcag atcttgaaag agcttgatat caaggctttg gttattatcg
    10081 gcggtgacga ttctaacacg aacgcttgcg tattggctga gtattacaag gctatcggtg
    10141 ccggcgtaca ggtaatcggt tgcccgaaga cgatcgacgg tgacttgaag aacgcccaga
    10201 tcgagacctc tttcggtttc gacacggctt gcaaggttta ctccgaggta atcggtaaca
    10261 tccaacgtga ctgtaactcc gcccagaaat actggcactt catcaaattg atgggtcgct
    10321 ccgcttctca tat
//
LOCUS       DBMDTB010000121        10290 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_1891_length_10290_cov_11.753558, whole genome shotgun
            sequence.
ACCESSION   DBMDTB010000121 DBMDTB010000000
VERSION     DBMDTB010000121.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 10290)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 10290)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10290
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1891_length_10290_cov_11.753558"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..224)
                     /locus_tag="ACZPB4_14765"
     CDS             complement(<1..224)
                     /locus_tag="ACZPB4_14765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HIR1099514.1"
                     /translation="MSTICAISTAPGVGGIAVIRVSGPDTFKICDRIFRPKKAGKSLS
                     TQKAYTLTYGSIVGNNDETIDEVIAAVFRAP"
     gene            complement(233..1351)
                     /locus_tag="ACZPB4_14770"
     CDS             complement(233..1351)
                     /locus_tag="ACZPB4_14770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HIR1099515.1"
                     /translation="MNTSKVYFTNLRTTPSSNLLDKMERLVKRAGIANIDFKNQFVAI
                     KIHFGEPGNLAYIRPNYAARLVSLLRELGAKPFLTDCNTLYSGRRSNAVDHLQSAMEN
                     GFNPMSAGCNVIIADGVKGTDYREIEIDGQYCKAPKIGAAIADADIIISMNHFKGHEQ
                     AGFGGALKNLGMGCASVGGKLELHCASQPRIDTEACKGCNICVKHCAHDAIHLNNNRK
                     AEIDYERCVGSGQCVALCQYDGAVMGEGDTSERLNYKIDEYTKAVLADKPHFHISFIM
                     NVSPECDCWNHNDAAIIPDLGIAASFDPVALDKACADMVINAPIIGGNKLAETHPHEH
                     LEGEDKFHLIHPDTNWQAGLRYAEEIGLGSQAYELITV"
     gene            1429..2613
                     /locus_tag="ACZPB4_14775"
     CDS             1429..2613
                     /locus_tag="ACZPB4_14775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HIR1099516.1"
                     /translation="MDLLQRNHQLLLKGINCTFLRYLHARIEWEDRLIGIFGSRGVGK
                     TTLLLQHIKLKFEDSREALYVNLDDFWFETHSLTDAVKEFLQAGGHYLFLDEIHFYSS
                     WMEEVSTLLDANPALKIVFATTSLYSQTEVRNGLRHEAAFYTMHPMSFREFLSYESIL
                     DKDPIPLEDILANHHDLVKEINAEMNIVPIYRNYLEHGCYPFYWQDPDMYYFRLQELV
                     RKEICRDLPSVVSISMSNLERAQKYFMMVAESAPLRPKSIDVTRKINMLRQQSDSLLR
                     FFHDVRLIYYSADQLGTTPAKQKVFMGDTNLLISFFGDKENRQLMCETYFLSQMRSVA
                     NVEFMENGDFLIGGKYIFAVGDPLRGYDRLRFVPDAYAAIYGLPKSVFNRMPAWILGF
                     SY"
     gene            2635..3381
                     /locus_tag="ACZPB4_14780"
     CDS             2635..3381
                     /locus_tag="ACZPB4_14780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HIR1099517.1"
                     /translation="MLECMKNRRSIRKYTDQDIPESLLNELLEVATRASNTGNMQLYS
                     VVVTRDPANKEKLAPAHFNQPMITGAPVVLTFCADANRFVKWAECRKAEAGFDNLQTF
                     IASTIDAMLFAQSFCNAAEEKGLGICYLGTTAYNADQIIEALSLPRLVVPIVTVTVGY
                     PAEPIPAQVERLPLAAVVQNETYTDFTPASIDALYSEKEALEVNKQFVRENNKETLAQ
                     VFTDVRYTKKNSEHFSEVLLKVLKQQGFMK"
     gene            complement(3371..4075)
                     /gene="rpiA"
                     /locus_tag="ACZPB4_14785"
     CDS             complement(3371..4075)
                     /gene="rpiA"
                     /locus_tag="ACZPB4_14785"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase A"
                     /protein_id="HIR1099518.1"
                     /translation="MKWDHSLIDTLEWGNQISHKEDKIKIADLIASKVENGQVIGVGS
                     GSTSYLALTRIAERIRTERLSILAIPTSLEIRMTCAQLGIPVTSLFSHKPDWTFDGAD
                     EVDSHFNLIKGRGGAMFKEKLLISSSPQTYILVDPSKKVERLGAKFPIPVEIFPEALT
                     HVEDRLHRLNPREIKLRMGQGKDGPIITENGNMILDVWMDYIPENTESTLKSITGVLE
                     SGLFMNYKVEVLGLTS"
     gene            complement(4089..4958)
                     /locus_tag="ACZPB4_14790"
     CDS             complement(4089..4958)
                     /locus_tag="ACZPB4_14790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HIR1099519.1"
                     /translation="MRTIPASELAIHSDGSVFHLHLKPEQLADRVVLVGDPARVTTVA
                     SYFESQECEVSSREFHTITGQYKGKRITVVSHGIGTDNIDIVLNELDALANIDFSTRT
                     IKPEFKQLSLVRIGTSGGLQPFVPIGTYVAAEKSIGFDGVIYFYANSNSVRDADLESE
                     LIKQLDWRLSGIWPYVVSADPSLIEQITRNDIIRGTTIAANGFYGPQGRELRLPLTDP
                     ELNRKIEAFDYNGRKITNFEMESSSLAGLAALMGHRAMTVCCIIAGRVDNHMNTDYKG
                     SLEKLIETVLDRI"
     gene            complement(5047..6039)
                     /gene="floA"
                     /locus_tag="ACZPB4_14795"
     CDS             complement(5047..6039)
                     /gene="floA"
                     /locus_tag="ACZPB4_14795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780036.1"
                     /note="flotillin-like protein involved in membrane lipid
                     rafts; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin-like protein FloA"
                     /protein_id="HIR1099520.1"
                     /translation="MEITFLPLILLGAAVLLLAIFFYYVPFLLWISAKVSGVNISLIQ
                     LFLMRIRKVPPYIITRAMIEAHKAGIKTLTRDELEAHYLAGGHVEKVVHALVSASKAN
                     IDLPFQMATAIDLAGRDVFEAVQMSVNPKVIDTPPVTAVAKDGIQLIAKARVTVRANI
                     KQLVGGAGEETILARVGEGIVSSIGSSESHKTVLENPDSISKLVLRKGLDAGTAFEIL
                     SIDIADIDIGKNIGAFLQMDQAQADKNIAQAKAEERRAMAVALEQEMKAKAQEARAKV
                     IEAEAEVPKAMADAFRTGNLGVMDYYKMKNIEADTSMREAIAKPTGAPSKPLKD"
     gene            complement(6050..6538)
                     /locus_tag="ACZPB4_14800"
     CDS             complement(6050..6538)
                     /locus_tag="ACZPB4_14800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HIR1099521.1"
                     /translation="MLLDIAIIVFLMVAAILLILAEIFLLPGITLAGIGGAIFAIGGV
                     VFAYTVGIWVGHLTLSLSIITFGIIFAWLLRSRSFNKIALKTDIDSKLISSRDLGIEP
                     GDEGITLSRLAPIGKARIKGINVEAKSQDELIDENTPIVVIRVDSYNVIVRPKEETNI
                     HA"
     gene            complement(6547..7995)
                     /locus_tag="ACZPB4_14805"
     CDS             complement(6547..7995)
                     /locus_tag="ACZPB4_14805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HIR1099522.1"
                     /translation="MKRLSKKLLYTLGVTLICGGMQLHAQSLDQAKKLYNDGKYAEAK
                     PVFEKLVKQAPSNASYNQWYGVCCFETGDLAGAEKHLKVAVKRRVQDAYRYLGEVYYQ
                     TYRFNEAEEMFDEYITLLTKKKQDVEPYQIRMDLANKASRMLDKVENVQIIDSLVVDK
                     DDLLSAYTLSEESGTLTTYQDFFQTNDPGNSSVYMNQKGDKIYYAHSTDGNHNCLFTQ
                     SKLMDQWGDEKQLPMNINSDADDGYPFVLSDGVTIYYASKGNGSLGGYDLFVTRYNIN
                     SDTYLTPEQLGMPYNSPFNDYMMVIDEAKQLGWFVSDRYQPEGKVCVYLFIPNDNRER
                     VDSEDIELKRARASIASIKDSWKPGSNYEELIHLAHTEIPYGRIEIKKDFTFPIHDDI
                     VYYTLDDIQSPEAKNYYEKVVSIHRQIKELNEKLESLRASYIKGNKAKREQLKPTILD
                     AEEKLNNLLAQPDEWEKKARNAEIVYLRNNHK"
     gene            8109..8855
                     /locus_tag="ACZPB4_14810"
     CDS             8109..8855
                     /locus_tag="ACZPB4_14810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine biosynthesis TtcA family
                     protein"
                     /protein_id="HIR1099523.1"
                     /translation="MAKLTEDERLFRKIEDKIKRAIFDYGLINDGDRILVGLSGGKDS
                     LALVDLLGRRSKIYCPRFEVVVAHIVMTNIPYCSDREYLRSCAEEHDLPFIVHETSFD
                     PSTDTRKSPCFLCSWTRRKALFEIAKAHKCNKIALGHHQDDILETLLMNLTHQGAFGT
                     MPPRLKMDKFDMEIIRPMCLVEERELIQVAAWKGYRKQLKNCPYESGSSRSDMKELLR
                     SLEAINPEARYSLWGSMTNIQEDYLPRKIR"
     gene            8857..9228
                     /locus_tag="ACZPB4_14815"
     CDS             8857..9228
                     /locus_tag="ACZPB4_14815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007748119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family protein"
                     /protein_id="HIR1099524.1"
                     /translation="MQSVYTILLLIVSNIFMTCAWYGHLKMKQQFSWFEHLPLFGVIL
                     FSWFLAFFEYCFQVPANRIGFRDNGGPFNLIQLKVIQEVITLVVFVAFSTIAFKGESF
                     KWNHALAFVFLVAAVYLVFKK"
     gene            complement(9356..10255)
                     /gene="miaA"
                     /locus_tag="ACZPB4_14820"
     CDS             complement(9356..10255)
                     /gene="miaA"
                     /locus_tag="ACZPB4_14820"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HIR1099525.1"
                     /translation="MNSLVILLGPTGVGKTELSLQVAERFGSPIISSDSRQLYKDLPI
                     GTAAPTPEQMARVKHYMVGTLSLTDYYSASNFEEDVVSLLSELHKTIPTVVMTGGSMM
                     YIDAVCKGIDDIPTVTPEIRDALYMQFETEGLAPILAELKEADPVHYEEVDRNNYKRV
                     IHAVEICRMTGKPYSSFRTNIKKERPFRIIKVGLNRDRDELCDRINQRVDQMMSEGLL
                     EEARRAYPFRHLNSLNTVGYKELFNYFSGEWTLDLAVEKIKRNSRVYARKQMTWFKRD
                     PEITWFHPDETEAIFTHLSQQII"
BASE COUNT         2576 a         2261 c         2451 g         3002 t
ORIGIN      
        1 ggggcacgga aaacagcggc gatcacctca tctatggttt cgtcattgtt accgacgatg
       61 gaaccatacg ttaaggtata agccttttgg gtagataaac ttttacctgc cttcttcggc
      121 cggaatatcc gatcacaaat cttgaaggta tccggtccgg agacacgaat cactgcgatt
      181 cctcctactc ccggagctgt agatatagcg caaattgtac tcattccgtc tattaaaccg
      241 ttattaattc atacgcttga gaacccagtc cgatttcttc cgcataacgt aggccggctt
      301 gccagttcgt atccggatga atcaaatgga atttatcctc tccctcaagg tgttcgtgag
      361 gatgagtctc ggctaattta ttacctccga tgataggagc gttgataacc atatcggcgc
      421 aagccttatc caaggccacc ggatcgaaag acgcagcgat ccccaaatca gggatgatgg
      481 cggcatcgtt atgattccag caatcgcatt ccggagatac gttcatgata aaactaatat
      541 ggaaatgggg cttgtctgct aatacggctt tcgtgtactc gtcgatcttg taattcaatc
      601 gctcggaagt atcaccttcg cccattacgg caccgtcgta ctggcaaaga gccacacatt
      661 gcccgctacc tacacaacgc tcgtaatcaa tttcggcctt tcggttgtta ttcaaatgga
      721 tggcatcgtg agcgcagtgc tttacacaga tgttacagcc tttacaagcc tccgtatcga
      781 tacggggttg tgaggcgcaa tgtaattcca gtttaccgcc tacgctggcg catcccatcc
      841 cgaggttttt cagcgcaccg ccgaaaccgg cttgctcgtg acctttgaaa tggttcatgg
      901 aaatgatgat atcggcatcg gcgatagcgg cacctatttt cggggccttg caatattgcc
      961 cgtcaatctc gatttcccgg tagtccgtac ctttcacgcc atcggcgatg ataacgttgc
     1021 aaccggcgga catgggattg aacccatttt ccatggcgct ttgaagatga tcgacagcgt
     1081 tggagcgacg gcccgagtat aaggtgttac aatcggtaag gaacggtttt gcgcctaatt
     1141 cacgtaacag gcttaccaag cgagcggcgt aattaggacg aatgtatgcc aaattccccg
     1201 gttcgccaaa gtggatctta atggctacaa attgattttt gaagtcgata ttggcgatac
     1261 cggcacgttt taccagacgt tccatcttat ccagcaggtt gctgctgggg gtcgtgcgca
     1321 aattagtaaa gtagactttg gatgtattca tctttttatt ggtttagtgt tgacaaaggt
     1381 acgaaaaaca cggaacattt tttatattcg cgtaaaacag atttgtatat ggacttgctt
     1441 cagcggaatc atcagctatt gttgaaagga ataaattgta cattcctgcg ttatttgcat
     1501 gcacggatag agtgggagga tcggttaatc ggcatcttcg gctctcgagg ggttggtaag
     1561 actaccttgt tgttacagca tattaagttg aaatttgaag attcacggga agccctgtat
     1621 gtgaatctgg atgatttctg gtttgagaca cattcattga ccgatgcggt taaggagttc
     1681 ctgcaagccg gggggcatta tttgtttttg gatgagatcc atttctattc gagctggatg
     1741 gaagaggtct caactttatt ggatgccaac cccgccttaa agattgtttt cgctaccact
     1801 tctttgtact cgcagacaga ggtgcggaac gggttaaggc atgaggctgc tttttatacc
     1861 atgcatccga tgtcgttccg tgaattcctt tcttacgaaa gcattctgga taaagatccc
     1921 attccgttgg aagatatctt agcgaaccat catgatttgg tgaaggagat caatgcggag
     1981 atgaatattg tgccgattta ccggaactat ctggaacatg gatgttatcc tttttattgg
     2041 caagacccgg atatgtatta tttccgtctg caagaattag tgagaaaaga gatttgccgg
     2101 gatttgcctt cggtggtttc tatttcgatg agtaatctgg aacgagctca aaaatatttt
     2161 atgatggtgg ctgagtcggc tcctttacgt ccgaaatcga ttgatgtaac ccgtaagata
     2221 aatatgcttc gtcagcaaag cgatagcctg ttgcgtttct tccatgatgt gaggcttatt
     2281 tattactcgg cagaccaact gggaaccact ccggccaagc agaaagtctt tatgggggat
     2341 accaacttgc tgatctcttt tttcggagat aaggagaatc ggcaattgat gtgtgaaacc
     2401 tatttcttaa gccagatgcg ttccgtggcg aacgtggaat tcatggagaa cggagatttc
     2461 ttgattggcg gtaaatatat cttcgccgta ggtgatccct taaggggata tgatcgtctc
     2521 cgcttcgtac ccgacgctta tgcggctatc tacgggttac cgaaaagcgt gtttaaccgt
     2581 atgccggcat ggatattagg atttagttat tgagaattta aaaataggat tgctatgtta
     2641 gaatgcatga agaatagaag aagtatccgt aaatatacgg atcaggatat cccggagtct
     2701 ttgctgaatg aattattgga agtggctact cgtgcctcga atacaggaaa tatgcaattg
     2761 tatagtgtcg tggttacccg cgaccctgcg aacaaggaga aactggctcc ggctcatttt
     2821 aaccaaccaa tgattacggg agccccggtg gtacttactt tttgtgcgga tgcgaaccgt
     2881 ttcgtgaaat gggcggagtg caggaaagcg gaggccggat tcgataattt acaaacgttt
     2941 atcgcttcga cgatagatgc gatgttgttc gcccagagtt tctgtaatgc cgctgaggaa
     3001 aaaggcttag gcatttgcta tctgggtacg acggcttata atgcggacca gatcattgag
     3061 gcgctttctc ttccccgtct ggttgtcccg atcgttacgg ttacggtggg ttatccggca
     3121 gagcctatac ccgctcaagt agaacgttta ccattggcgg ctgtggtaca aaacgagact
     3181 tatacggact ttactccggc ttccatcgat gccttgtata gtgagaaaga ggcattagag
     3241 gtgaataagc agtttgtaag ggagaataat aaggaaacac tggcgcaggt ctttacggac
     3301 gtacgctata cgaagaaaaa tagtgaacat ttctccgagg tgctcttgaa ggtattgaaa
     3361 caacaaggat tcatgaagta agccctaata cttctacctt atagttcata aagagtccac
     3421 tctcgagtac gcctgtaatc gacttgaggg tggattctgt attttcaggg atatagtcca
     3481 tccatacgtc aaggatcata ttgccattct cggtaatgat cggtccatcc ttaccttgtc
     3541 ccatacgaag ttttatctca cgggggttca agcgatggag cctgtcttct acatgggtga
     3601 gggcttccgg aaaaatctct actgggatcg ggaatttagc tcccaacctc tccactttct
     3661 tggaaggatc gacgagtata taggtctgcg gactggaact gatcaatagt ttttccttga
     3721 acatggcgcc tccacgccct ttgatcaagt taaaatggga atctacttca tcagccccat
     3781 cgaaggtcca gtccggcttg tgggaaaaca ggctggtaac cggaatgcct agctgggcgc
     3841 aagtcatccg gatttctaaa gaagtgggga tcgccaaaat ggaaagacgt tccgttcgga
     3901 tacgttccgc tatgcgagtc aacgctagat aggaggtcga accggagcca acgcctatga
     3961 cttgtccgtt ttcgacttta gatgcgataa gatccgctat ctttatttta tcttccttat
     4021 gggagatctg atttccccat tccaacgtat cgattaatga atgatcccac ttcatggtct
     4081 tgatattatt atatacggtc taatacagtt tcaatcagtt tttccaaaga acctttataa
     4141 tccgtattca tatgattatc cacacgtccg gcgataatac agcatacggt cattgcccgg
     4201 tgtcccataa gggcggccag acctgctaaa gaggagctct ccatctcgaa gttcgtaatc
     4261 tttcgcccgt tgtaatcgaa agcctctatt ttccggttca attccggatc ggtcaagggc
     4321 aatcggagct cacgtccttg cggcccgtag aagccattgg ccgcgatagt cgttccccgg
     4381 ataatatcat tacgggtgat ttgctcgatc aacgatggat ctgccgatac gacataaggc
     4441 catatgccgc taagccgcca atcaagctgt tttattaatt cagattccaa gtctgcgtca
     4501 cgaacggaat tactatttgc gtagaaataa atgactccat cgaatccgat cgatttctcc
     4561 gctgccacat aagtcccgat cgggacaaat ggctgtaacc ctccggaagt cccgatacga
     4621 actagggaaa gttgcttgaa ttccggcttg atcgtacggg ttgagaagtc aatattagcg
     4681 agagcgtcca actcatttaa tacgatatca atattatctg taccgatgcc atgggataca
     4741 accgtgatac gttttccctt gtattggccc gtgatggtat gaaactcccg gctggaaacc
     4801 tcacattcct gagactcaaa ataggaagcg acggttgtaa cccgtgcggg atcgccaaca
     4861 agtaccacac gatccgcgag ttgttctggt tttaaatgca ggtggaaaac actaccatct
     4921 gaatggatcg ctaattctga agcggggatt gttctcatat tcgatcagct aattaagttt
     4981 acttttaatc ataaaagggc aaggtgcgac cctgcccttg gagatagttc catgtatata
     5041 actattttag tcctttaatg gttttgatgg agcaccggtc ggtttagcta tcgcttcacg
     5101 catagaagtg tccgcctcga tgttcttcat cttgtaatag tccattacgc ctaggtttcc
     5161 tgtgcggaaa gcgtctgcca ttgccttggg aacttccgct tctgcctcga tcaccttggc
     5221 acgggcttct tgagctttcg ccttcatctc ttgctcgagg gcgacagcca tcgcacgacg
     5281 ttcctcggct ttcgcctgag cgatattctt atccgcttga gcttggtcca tttgcaagaa
     5341 agcgccgatg ttcttaccta tatcgatatc ggcgatatcg atggaaagga tttcgaaagc
     5401 tgttccggcg tcaagccctt tgcgaagcac taatttcgag atggaatccg gattttccaa
     5461 tacagtctta tggctttcgg atgaaccaat ggaagatacg ataccttcac ctacacgggc
     5521 taagatcgtc tcttctcctg caccacccac taattgcttg atattcgcac gaacggtgac
     5581 acgtgccttg gcgattaact ggattccgtc tttcgcaacc gctgttaccg gaggggtatc
     5641 gatcactttc ggatttaccg acatttgtac agcctcgaat acgtcacgtc cggccaagtc
     5701 gatagcggta gccatctgga aaggaaggtc gatattcgct tttgacgcgg aaaccagcgc
     5761 atgcactact ttctcgacat gtccacccgc taaatagtgc gcttccagct cgtcgcgtgt
     5821 aagcgtcttt attcctgcct tatgcgcttc gatcatcgca cgagtgatga tgtagggagg
     5881 aacctttcgg atacgcatca agaataactg gatcaaggag atattgactc ccgatacttt
     5941 ggccgagatc cataacagga acggcacata atagaaaaag attgccagca gaagtactgc
     6001 ggcccccaat aggataagtg gcaaaaaggt tatttccata tatataaaat taagcgtgaa
     6061 tatttgtttc ttctttagga cggacaatta cgttgtaact gtctaccctg atcactacga
     6121 tcggcgtgtt ctcatcgatt aattcgtctt gagatttcgc ttccacgtta atacctttaa
     6181 tccgggcctt gccgataggg gctaagcgtg agagcgtgat cccctcgtct ccgggttcta
     6241 ttccgagatc cctgctggat atcagcttgg aatcgatatc tgtctttaaa gcgatcttgt
     6301 taaaagaccg ggaacgcaat aaccaagcga agattattcc gaatgtaatg attgataagg
     6361 ataaagtcag atgccctacc catataccta ccgtataagc gaaaacgact ccgccgatag
     6421 cgaaaatagc cccgcctata cccgcgagtg ttattcccgg aagaaggaat atctcagcca
     6481 gtatcagtag gatggccgct accatgagga agacgatgat ggctatgtcc agtagcatag
     6541 ttcttcttat ttatggttgt ttcttaggta tacgatctct gcgttacgtg cctttttctc
     6601 ccattcgtcc ggttgagcga gcaggttgtt taacttttct tccgcatcaa gaatcgtagg
     6661 cttcagttgt tctcgcttcg ccttattccc tttgatgtag ctggctcgta aactctctag
     6721 tttctcattt agctccttga tctgtctatg gatggaaact actttctcgt agtagttctt
     6781 cgcttccgga ctttggatat cgtccaaggt gtaataaacg atatcatcat ggatcgggaa
     6841 cgtgaaatct ttctttattt ctatacgtcc ataaggaatc tcggtatggg ctaaatgaat
     6901 aagctcttcg taattcgatc cgggtttcca tgaatccttg atcgaggcaa tagaggcccg
     6961 ggcacgtttt agttcgatat cctcgctatc tactcgctcg cggttgtcgt tcgggatgaa
     7021 taagtatacg cagacttttc cttccggttg ataacgatcg gaaacgaacc atcccaattg
     7081 cttggcttcg tcgatcacca tcatataatc gttaaacggg gagttatagg gcatgcccaa
     7141 ttgctccggt gtaaggtaag tatcggaatt gatgttgtaa cgggtgacga ataaatcata
     7201 tccgcccaga gagccgttcc ctttggatgc gtaataaatc gttacgccat cggatagcac
     7261 gaatggatac ccatcgtcgg cgtcactatt gatattcatc ggtaactgtt tctcgtctcc
     7321 ccattgatcc atgagcttgg attgggtaaa aagacaattg tggttaccgt ctgtcgagtg
     7381 ggcgtaataa atcttatccc ccttctggtt catgtatacc gatgagttgc ccggatcgtt
     7441 tgtctggaag aaatcttggt aagtggtcaa cgtaccgctt tcctcgctta aggtataggc
     7501 tgataagaga tcatctttat caacgaccaa gctatcgata atctggacat tctctacctt
     7561 atcaagcata cggcttgctt tgttcgccaa gtccatacgg atttggtaag gttccacatc
     7621 ttgtttcttt tttgttagga gggtgatgta ttcgtcgaac atctcttcgg cttcgttaaa
     7681 acgataggtc tggtagtata cttctccaag gtatcgataa gcgtcttgta ccctacgctt
     7741 tacggcgacc ttaagatgtt tctccgctcc tgctaaatct ccggtctcga aacagcaaac
     7801 accataccat tgattataag aggcattgct tggcgcttgt ttcactagtt tctcgaacac
     7861 aggtttggct tctgcgtatt tcccgtcgtt atataatttt tttgcctgat caagactttg
     7921 cgcatgtagt tgcattcctc cgcatatgag tgtaactcct agcgtataaa gcagcttttt
     7981 ggataaccgt ttcattttgt ctattctaga ttatatatag ttatgcagtt tcaaagataa
     8041 gaatattttt gtagaggcat acaaatcgaa aagataaata tataattttg cgcccgtaaa
     8101 ggaagtatat ggcaaaattg acagaggacg aacgtttgtt tcgcaagata gaggataaga
     8161 taaagagagc gattttcgac tatggcttga tcaatgatgg cgaccggatc ttggtcgggt
     8221 tgtccggagg aaaagattcc ttggccttgg tggatttact ggggcgcagg tcgaaaatct
     8281 attgtcctcg gtttgaggtc gtggtagcac atatcgtgat gacgaatatc ccttattgtt
     8341 cggatcggga atatcttaga agttgcgcag aggagcatga tttgcctttc attgtccatg
     8401 agacaagttt cgatccttct acggacactc gtaaatcccc ctgcttttta tgctcttgga
     8461 ctcgccggaa agctttgttt gagatcgcta aggcgcataa atgcaataag attgcgctag
     8521 ggcatcatca agatgatatc ctagagacac tgttgatgaa cctgacccac caaggggctt
     8581 tcggaacaat gcctccccgg ttgaaaatgg ataagtttga tatggagatt atccgtccga
     8641 tgtgtctggt ggaagagagg gagttgattc aggtcgccgc atggaaaggg taccggaaac
     8701 aattgaagaa ctgtccttat gagtcgggtt ccagtcgttc ggatatgaaa gagctgctga
     8761 gaagtctgga agcgatcaat ccggaggctc gttacagtct ttgggggagc atgacgaata
     8821 tacaagaaga ttatttacct cgaaaaataa gataatatgc aaagtgttta tacgatttta
     8881 ttgttgatcg tgtctaatat ttttatgaca tgcgcttggt atggtcattt gaagatgaag
     8941 caacaattca gttggtttga gcatcttcct ttgtttggcg taatcctgtt tagttggttt
     9001 ctcgcttttt ttgagtattg tttccaagta ccggcgaatc gcatcggttt ccgggataac
     9061 gggggaccgt tcaacttgat tcaattgaaa gtgatccaag aggtgattac gttggtggta
     9121 ttcgtggcct tcagtaccat cgcttttaag ggggagtcgt ttaaatggaa ccatgcgctt
     9181 gctttcgtat tcttggtagc ggcggtttat ctggttttca agaaataaag tcgttgcgtt
     9241 tggctttgat aatcagcgga aaaccttgat gcctattgta agatgcttac aatgcctatt
     9301 caagcatgtt tataatgccc attgtaagct ccttataatg ggcattgtta aaacgctata
     9361 tgatctgttg gctcagatgt gtaaatatag cttcggtctc atccggatgg aaccatgtta
     9421 tttctgggtc ccgtttaaac caagtcattt gcttccgggc gtagacccgg gagtttcgtt
     9481 tgattttctc cacggcgagg tctaatgtcc attctccgct gaagtaattg aataattctt
     9541 tataacctac cgtgttcaag gaattcaaat gacggaaggg ataagcccgg cgagcctctt
     9601 ccaataatcc ttcgctcatc atttgatcta cacgttggtt gatgcggtcg cataattcgt
     9661 cacgatctct attaagccct actttgatga tccggaacgg acgctctttc ttaatgttcg
     9721 tgcggaagga ggagtaaggc ttgcctgtca tccggcaaat ctctacggca tggatcactc
     9781 gtttataatt attccggtcc acttcctcat aatggacagg gtctgcttct tttaattcag
     9841 cgaggatagg ggctagtccc tcagtttcaa attgcatgta tagggcatcc cggatctccg
     9901 gtgtaaccgt cgggatatcg tcaatacctt tacatacggc atcgatgtac atcatagagc
     9961 ctccggtcat tacgacggtc gggatcgttt tatgtaattc ggataggagg gagaccacat
    10021 cttcctcgaa attgctggcg ctgtaataat cggtaagtga gagagtgcct accatataat
    10081 gcttgacacg tgccatttgt tccggtgtag gggcagccgt gccgatcgga aggtctttat
    10141 agagctgacg ggagtcggaa gagataatcg gagagccgaa acgttccgcc acttggaggc
    10201 ttaactcggt ctttccgact cctgtcggcc caagtaatat aacgagggaa ttcatcaaaa
    10261 gcgctcgtcg tcgtaaggat tatccatcgg
//
LOCUS       DBMDTB010000122        10053 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_1937_length_10053_cov_9.930265, whole genome shotgun sequence.
ACCESSION   DBMDTB010000122 DBMDTB010000000
VERSION     DBMDTB010000122.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 10053)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 10053)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10053
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1937_length_10053_cov_9.930265"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..351
                     /locus_tag="ACZPB4_14825"
     CDS             <1..351
                     /locus_tag="ACZPB4_14825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane beta-barrel protein"
                     /protein_id="HIR1099526.1"
                     /translation="NNLFNLGKYTRIQLDGSFVGPSVTTQGRTDAYWYANVAVRQQLC
                     NRKLTATLAFRDIFRSAKYISDIQTADLRSLTRIKPKYPQITLTLSWTFNSFKAKSTQ
                     AKEDRSEMFEGIKH"
     gene            complement(505..1578)
                     /locus_tag="ACZPB4_14830"
     CDS             complement(505..1578)
                     /locus_tag="ACZPB4_14830"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF013884.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HIR1099527.1"
                     /translation="MNQSEKVLLNSRLINQVKEANNFDFIRFFLAYSVMFNHFSTLTE
                     TDPFWFVSGGFRVKGFFIISGFLVMFSFLRTPNTRIFFRKRIQRIMPAYSLTILLCAL
                     IGLFLTSLSCREYLTSSSLYTYLICNLLTFNFLSPDLPGVFDTNPLQAMNGSLWTIKV
                     EFMLYIIIPIIYWLLKRYNKLVCLLLIYILSFIYSTTCNYLDDMTHNPIYEFMKRQFP
                     GQMMYFCSGIIILAYFPVFRKYMRYLFPVSLFLLLGREYLLLSIFEPIALASIIITVA
                     YGFKWLHVFNRMGNFSYGIFLIHFPIIQIFIHYGLDRYSLILTLALTTILSTGLGMLS
                     WKYIEKPCLYHPKKKNQMNAMIG"
     gene            complement(1583..3913)
                     /gene="porZ"
                     /locus_tag="ACZPB4_14835"
     CDS             complement(1583..3913)
                     /gene="porZ"
                     /locus_tag="ACZPB4_14835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0160303 - protein secretion by the type IX
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type IX secretion system anionic LPS delivery
                     protein PorZ"
                     /protein_id="HIR1099528.1"
                     /translation="MRHILTIILFSFFSFTVLAANFNTTGWKTYLSYNNTNSVEESND
                     QVFVVAEGSLYTYGKEDNSIKQYYKGNGLNDNTISLIRYNKQTKSLLIIYDNSNIDIL
                     EGGVATNLPYLSTSTSIRDKQINSVLVHDEYAYLSTAFGIVVVNMAKKEIKDTYKLSL
                     NITSCAIQNGNIYASTTNKAEVSSGIIYASLKENLLDKANWKPYELSNLSDSHTISAI
                     ASFKNTLFYLVSQQGIFYENNGELSRIINSSTLKYMKVIGEKLACIDNSRVFIVSDTQ
                     KFDQINLSINDISTYQTDKYWIAEGSKGLRSIQRKGSNSFEALNEPIILDGPYSNSAF
                     DIVCKNDKVYMIIGGKDLLNGKRFDKGGYILTYDYDKWSFIDPKEAQKKLNLPRNPRD
                     YTSIAVTTDDSNDEIVYASSMGDGVIQYKNGTPVQSYNEKNAFKETAGGYGSGYCYID
                     GLAFDKNGNLWMTSSEVNHAVLVLDKAGAWHRLDIEQLRGVYTINDILITSTNDKWIY
                     VPRNTPKLVMIPNSESLDEVSSYEFTTLIDTDGKELTPSNYTCVAEDKDGYIWVGTNR
                     GAVYFTKPRISSAEDKAATRCTRVKYTNEETGNLAYFLDNVVVTTLKVDAGNRKWIGT
                     KGNGVYVLDNDNETIVYQFNTTNSPLLSDNIYDIEINDKTGEVFIGTDKGLNSYQGEA
                     SEGKSDYSEIYAYPNPVRPEHMDKVTIVGLMDNSNVKITDLNGNIIYQTKSLGGQAIW
                     NCRNANGSRVATGVYLVLASTEEASESVVTKIIVVK"
     gene            complement(3915..4496)
                     /locus_tag="ACZPB4_14840"
     CDS             complement(3915..4496)
                     /locus_tag="ACZPB4_14840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0009143 - nucleoside triphosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="non-canonical purine NTP diphosphatase"
                     /protein_id="HIR1099529.1"
                     /translation="MKLVFATNNQHKLDEVRKITAGYAEIISLSDIDCHDDIPETADT
                     LEGNALLKARYIKEKFGYDCFADDTGLEVEVLNNAPGVYSARYAGTEHDSEANMNKLL
                     SEMNHKENRKARFRTVIALVLDGKEYTFDGIVNGSITTEKRGDSGFGYDPIFMPDTYT
                     QTFAEMGNDTKNQISHRAKAVMKLTSFLSDYNC"
     gene            complement(4584..5462)
                     /locus_tag="ACZPB4_14845"
     CDS             complement(4584..5462)
                     /locus_tag="ACZPB4_14845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HIR1099530.1"
                     /translation="MNLKLTKIYFSVQDYLMILFGTLLYGFGFNAFILSNEIVTGGVS
                     GICALIFFASNGLIPVSVSYFVINVALLVVALKILGLKFLIKTIFGVFSLSASLSLFE
                     WLLKGQPILHDQPFMAIIIGAFMCGAGLGLVFSANGSTGGTDIIGAVINKYKNISIGR
                     ILLFCDFFIISSSFFLFHNVDKIVFGFVEMVISNYVLDMVLNGNRQSVQFLIFSQKYD
                     EIADRIIHDLGRGCTILDGEGGYSRKPVKVVVLLAKKSESVSIFRIVKRIDHQAFISQ
                     SIVRGVYGEGFDQIKT"
     gene            complement(5459..8299)
                     /gene="leuS"
                     /locus_tag="ACZPB4_14850"
     CDS             complement(5459..8299)
                     /gene="leuS"
                     /locus_tag="ACZPB4_14850"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HIR1099531.1"
                     /translation="MEYNFREIEKKWHDYWIAEKVYKVEKDTNKPKYYVLDMFPYPSG
                     AGLHVGHPLGYIASDIYSRFKRLQGFNVLHPMGYDAYGLPAEQYAIQTGQHPEITTKN
                     NIARYREQLEKIGFCYDWSREIRTCDPEYYKWTQWAFIRMFNSYYCNDEKQARPISEL
                     IQAFETSGTEGLNVACGEELSFTADEWKAKSDKEKQEILLNYRIAYRGETMVNWCAAL
                     GTVLANDEVVNGVSERGGYPVEQKIMRQWCLRVSAYAQRLLDGLDTIDWTDSLKETQK
                     NWIGRSEGAEVRFKVKDSDREFTIFTTRADTMFGVTFMVLAPESELVQQLTTADQKAE
                     VDAYLDRTKKRTERERIADRQVTGVFSGSYAINPFTGEAVPIWISDYVLAGYGTGAIM
                     AVPAHDSRDYAFAKHFGLEIRPLVEGCDVSEESFDAKEGIVCNSPRAGVTPYCDLSLN
                     GLTIKEAIAATKKYVKDHDLGRVKINYRLRDAIFSRQRYWGEPFPVYYDADGMPQMLP
                     EECLPLLLPEVDKFLPTETGEPPLGHAVKWAWDTVNQKVTEVSKIDNQTIFPLELCTM
                     PGFAGSSAYYLRYMDPRNDKALVAKDVDEYWRNVDLYIGGTEHATGHLIYSRFWNKFL
                     FDLGIVCEEEPFKKLINQGMIQGRSNFVYRINGTNKFVSLNLKDQYEVTPIHVDVNIV
                     SNDLLDIEAFKNWRPEYNDAEFVLEDGKYICGWAVEKMSKSMFNVVNPDMIVEKYGAD
                     TLRLYEMFLGPLEQSKPWDTNGIDGVHRFLKKLWGLFFGNTDTLQVTDAEPTADELKS
                     LHKLIKKVTFDIEHFSYNTSISAFMICVNELTSLKCSKRAILEPLITLLAPFAPHITE
                     ELWHQLGHDTTICDAQWPEHNEEYLVEKSVTYVISFNGKARFNLELPADISREDAEKA
                     ALSHENSAKWMEGKTVKKVIVVPGKIVNIVVG"
     gene            complement(8389..8946)
                     /locus_tag="ACZPB4_14855"
     CDS             complement(8389..8946)
                     /locus_tag="ACZPB4_14855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6N domain-containing protein"
                     /protein_id="HIR1099532.1"
                     /translation="MELQAIQNKIYEIRGQKVMLDFDLAEMYGTETAQLKRAVRRNIE
                     RFPNDFMFTLTIQEFNNLKNNMVCQIGISKKGGNQYAPFAFTEQGIAMLSSVLRSDTA
                     IKVNISIMRAFVGIRQIISSSSPLLELQQEVKELKAYIEEAFADYNDINEDTRTQLEL
                     INLSLAELQAKRTENQSRPRIGYVK"
     gene            complement(8971..9534)
                     /locus_tag="ACZPB4_14860"
     CDS             complement(8971..9534)
                     /locus_tag="ACZPB4_14860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6N domain-containing protein"
                     /protein_id="HIR1099533.1"
                     /translation="MELQTIQNKIHEIRGMKVMLDFDLAEMYGTETAQLKRAVRRNIE
                     RFEGDDFMFELTKEELSRCQFGILNKGRGSNFKYKPFAFTELGVAMLSSVLNSKTAIE
                     INRNIMRVFVAIRNYTLQATTSSIEIKELQERIKSLEMANEETLCAINDLSEDTQKSL
                     DDIYIALSELATKKKNNAKRPKIGYIK"
BASE COUNT         2739 a         2116 c         2069 g         3129 t
ORIGIN      
        1 aataacctgt ttaatctggg gaaatacacc cgtatccaat tggatggtag ttttgtaggc
       61 ccttccgtaa cgacgcaggg ccgtacggac gcttattggt atgcgaacgt agccgtccgc
      121 cagcaactat gtaaccgaaa actaaccgcc accttagctt tccgggatat tttccgttcc
      181 gccaaatata tcagcgatat ccaaacggca gatttacgtt ccctgacacg tatcaaaccc
      241 aaatatccac aaatcacgtt gacgttgagt tggacattta atagtttcaa ggccaaatcc
      301 acccaagcga aagaagatcg ctcggagatg ttcgagggta taaagcattg atatcgtatc
      361 tttactgtat tggtttgtct tcgggaaaca actacgacta caaataaatt ctgcaatcgt
      421 agttgtttcc ctcttttacg gatggtggga tttagttctt ggcattaata gctgctaaag
      481 gagcggagaa gataacagat cagatcatcc gatcattgcg ttcatctggt ttttcttttt
      541 aggatgatat aaacaaggtt tctctatgta tttccaagat aacataccca atccggtgct
      601 aaggatagtg gtaagagcca atgtcaatat caagctatac cgatcaagtc cgtaatgaat
      661 gaatatttga atgatcggga aatgaattaa gaagatacca tacgagaaat ttcccatccg
      721 attgaataca tgtaaccact tgaatccata agctaccgtg ataatgatag aggctagagc
      781 gataggctcg aaaatactca gcagcagata ctctctaccc aataaaagaa ataggctgac
      841 agggaacaaa tatctcatat attttcgaaa aacagggaaa taggcaagta tgataatacc
      901 ggaacaaaag tacatcattt gtccggggaa ttgtcttttc atgaattcat aaatagggtt
      961 gtgtgtcata tcatctaaat aattacacgt tgtcgagtag atgaaagata agatataaat
     1021 aagaagtagg cataccaatt tattgtatct tttcagtaac caatagataa tgggtataat
     1081 gatatatagc atgaattcaa ccttgatagt ccataaagac ccattcatcg cttgtaaagg
     1141 attggtatcg aatacgccgg gtaaatccgg cgataaaaag ttaaatgtaa gtaaattaca
     1201 gataagatag gtgtataagc tagaagaggt gaggtattcc ctgcaggata aagaggtaag
     1261 gaataatccg attaaggcac ataataaaat agtcaagctg taggcgggca taatacgttg
     1321 aatacgttta cggaaaaaaa tccgggtatt aggcgtacgt aagaagctaa acataacaag
     1381 aaatccacta ataataaaga aacctttcac tcgaaatcct ccgctaacaa accaaaaagg
     1441 atctgtctct gtcagtgtgc tgaaatggtt gaacatgaca gaatacgcaa gaaagaagcg
     1501 aataaaatca aaattattcg cttcttttac ttgatttatt aatctggagt tgagtaaaac
     1561 tttctctgat tgattcattg ttctatttga ctacaatgat ttttgttacg acgctctctg
     1621 aggcttcctc cgtggaagct agtacaagat atacgcctgt cgctacacgt gatccgtttg
     1681 cgttccggca attccagata gcttgccccc ccaaggattt agtttgataa ataatatttc
     1741 cgtttaaatc cgtgattttt acattcgaat tatccattaa tcctacaatc gttactttat
     1801 ccatatgttc gggacgtacc ggattaggat atgcgtagat ctccgagtaa tcagatttac
     1861 cttccgaagc ttctccttga taggaattta gtcctttatc ggtaccgata aaaacctcac
     1921 cggtcttatc gtttatctct atatcgtata tgttatcgga aaggagcggg ctattggtcg
     1981 tattaaattg ataaacgatt gtctcattat cattatctag aacatagacg ccatttcctt
     2041 tggttccaat ccattttcga ttacctgcgt ctacttttag ggtcgtgacg acaacgttat
     2101 ctaagaaata agcgagattg ccagtttcct cattggtata ttttaccctt gtacaacgtg
     2161 tagcggcttt atcctcagcg gaagagatcc taggtttagt gaaatatacg gccccccgat
     2221 tcgtaccaac ccagatatat ccatccttat cctcggctac gcatgtataa ttactaggag
     2281 tcaattcttt tccgtcggta tcaataagtg tagtaaactc atacgaggaa acttcgtcta
     2341 aagactcgct attcggtatc attacaagtt taggggtgtt acgaggcaca taaatccatt
     2401 tgtcgttcgt ggaggttata agtatatcgt ttattgtata aactcctcta agttgctcga
     2461 tatccaaacg atgccatgct cctgctttgt caagaacaag taccgcatgg ttaacctctg
     2521 agcttgtcat ccacaaattt ccatttttat caaaggccag tccatctata taacaataac
     2581 cggacccata gcctcccgcg gtttctttaa aggcattctt ttcattgtat gactggacgg
     2641 gagttccatt cttatattgg ataacgccat cacccatgga agaggcgtat acgatctcat
     2701 cattagaatc atcggtcgtt acggctatac ttgtatagtc tcgtggattt cttggtaaat
     2761 tgagtttctt ttgggcttct ttaggatcga taaaagacca tttatcataa tcgtatgtaa
     2821 gaatataacc tcctttgtcg aagcgtttac catttaggag gtctttgcct cctatgatca
     2881 tatatacttt atcattttta caaacaatat cgaatgcgct attgctgtaa ggtccgtcta
     2941 aaatgatagg ttcattaaga gcctcaaaac tatttgatcc tttccgttgg atagaacgta
     3001 gccctttgct tccttccgct atccaatatt tgtctgtttg ataggtactg atatcattga
     3061 tacttaagtt tatttggtca aacttttgcg tatcggatac gatgaaaacc cttgagttat
     3121 ctatacatgc taatttttcg cctattactt tcatgtattt tagggttgag ctatttatta
     3181 ttcgggaaag ctctccattg ttttcataga agataccttg ctgactgacc aagtagaaca
     3241 aagtattctt gaatgaagcg atagctgaga tcgtatgact atcggaaagg tttgataatt
     3301 catagggctt ccagtttgcc ttatccagta ggttttcttt taatgaggcg tatataatcc
     3361 ccgaagatac ttctgcctta ttggttgtag aggcatatat attgccattc tgtatggcac
     3421 acgatgttat atttaaggaa agcttgtagg tatcttttat ttcctttttg gccatattga
     3481 ccacgacgat accaaatgct gtcgataaat aggcatattc atcgtgtacc aatactgaat
     3541 tgatttgttt gtctcttatg gacgtactgg tcgacagata aggtagattt gtcgccactc
     3601 ctccctcaag tatatctata tttgaattat catagataat aaggagtgat tttgtttgtt
     3661 tattatagcg gatcaaagaa atcgtattat catttaatcc gtttccttta taatattgct
     3721 taatactatt atcttctttt ccatacgtat aaagagatcc ttccgctacc acaaatactt
     3781 ggtcgttcga ttcctctacg ctgtttgtgt tattgtaaga aagatacgtt ttccatccgg
     3841 ttgtattaaa attcgcggct aatacagtga atgaaaagaa tgaaaataga atgatagtaa
     3901 gtatatgtct catattaaca attgtaatca gataaaaatg atgttaactt catgacggct
     3961 ttcgcacgat ggctgatctg gttttttgta tcgttaccca tctcggcgaa agtttgtgta
     4021 taggtatcag gcatgaatat aggatcgtat ccaaatccgc tatctccgcg tttttcggta
     4081 gtgatagagc cattcacgat accgtcgaag gtatattctt ttccgtcaag gactagagct
     4141 atgaccgtgc ggaaacgtgc ttttctgttt tctttatgat tcatttcgga caacagcttg
     4201 ttcatattag cttccgagtc gtgctctgtt cctgcgtaac gagccgaata gactcccgga
     4261 gcattattca atacctcgac ttctaatccc gtgtcgtcag cgaaacaatc atatccgaat
     4321 ttctccttga tatagcgggc ttttagcaaa gcatttccct ctaaggtatc tgccgtctcg
     4381 gggatatcgt catggcaatc tatatcggat aaacttatga tttccgcgta tccggcggtt
     4441 atcttgcgga cctcgtccag tttgtgttga ttatttgtcg cgaatacaag tttcatattt
     4501 cgtaatctat taaataagaa agcatttcta tacggtagat atataacgta tggaaatgct
     4561 ttaaattgtt tgtatattct tttttaagtc tttatctgat cgaacccctc accatatacc
     4621 cctcggacaa tgctttggga gatgaacgct tggtggtcta tccgtttcac gatccggaag
     4681 atggagacgg attcggattt cttggcgagt agtacgacta ccttgacggg tttgcgggaa
     4741 taaccgccct cgccgtccag tatcgtgcag ccacggccta agtcatggat gatgcgatcc
     4801 gctatctcgt cgtacttctg ggagaagatg aggaattgta cggattggcg gttaccgttc
     4861 aataccatgt cgagaacgta attgcttatg accatctcca cgaaaccgaa aacgatcttg
     4921 tccacgttat ggaacaggaa gaaagaggaa ctgatgatga agaaatcgca aaacagaagg
     4981 atacgtccga tcgatatatt cttatattta ttgattaccg caccgataat atccgtacct
     5041 ccggtactac cgttggccga gaataccagt cctagtccgg caccacacat aaacgctccg
     5101 attatgatag ccataaacgg ctggtcgtgc agtataggtt gtcctttcag cagccactcg
     5161 aagagagaga gagaagccga gagtgagaaa actccgaaaa tagtttttat caagaatttt
     5221 agaccaagga tctttaaggc taccaccaac aaggctacgt tgatgacaaa ataagatacg
     5281 gataccggga tcaatccatt ggaggcaaag aagatcaacg cacagatacc acttacccca
     5341 cctgtcacga tttcgttgga aaggataaag gcgttgaatc cgaatccgta taatagagtt
     5401 ccgaacagga tcattagata atcctgtacg gaaaaataga tttttgtgag ttttaagttc
     5461 atcccactac gatattaacg attttgccgg gaacgacaat taccttctta acggtcttgc
     5521 cttccatcca cttcgctgag ttctcatggc tcaaggccgc cttctcagcg tcttcacggg
     5581 agatatctgc cggaagttcg aggttgaaac gggctttacc attgaatgag atgacgtagg
     5641 taactgattt ttctaccaga tactcttcgt tatgttccgg ccactgggca tcgcagatgg
     5701 tcgtatcatg tcctaattga tgccatagct cttccgtgat gtggggagcg aacggagcca
     5761 ataaggtgat cagcggctcc aagatggcgc gcttgctgca ttttaagctc gttaactcgt
     5821 tcacgcaaat catgaaggcg ctaatggacg tgttgtatga gaaatgctcg atgtcgaacg
     5881 ttactttctt gatcagctta tgcaaggatt tcaattcgtc ggccgtaggc tcggcatcgg
     5941 taacttgcag ggtatccgta ttgccgaaga acaagcccca aagcttcttt aagaaacggt
     6001 gtacgccgtc gataccgttc gtatcccaag gcttggattg ctccagcggg cctaggaaca
     6061 tctcgtacaa acgtagggta tcggcaccat atttctcaac gatcatatcc gggttcacta
     6121 cgttgaacat ggatttggac atcttctcga ccgcccatcc gcagatatat ttaccatctt
     6181 ccaatacgaa ctctgcgtcg ttgtattccg gacgccagtt cttgaaagcc tctatatcca
     6241 acagatcgtt agatacgata tttacgtcta cgtggatagg ggtgacctcg tattggtctt
     6301 tcaagttcaa ggaaacgaat ttattggttc cgttgatgcg gtacacgaag ttcgaccgtc
     6361 cttggatcat accttggttg atcaatttct tgaacggctc ttcctcgcaa acgataccca
     6421 agtcgaataa gaacttattc cagaaacggc tgtaaatcaa gtggccagta gcgtgttccg
     6481 taccaccgat atataaatcc acgtttctcc aatattcatc cacgtcttta gctaccaagg
     6541 ctttatcatt acgcggatcc atatagcgca aataataagc ggaagaaccg gcgaagcccg
     6601 gcatcgtaca aagctccagc gggaagatcg tctggttatc gatcttcgat acctcggtga
     6661 ctttttggtt taccgtgtcc caagcccatt taacggcgtg tcctaatgga ggctcgcccg
     6721 tctcggtagg caagaattta tctacttccg gcagcaacaa gggcagacat tcttccggca
     6781 acatctgagg catgccatcg gcgtcgtaat ataccgggaa cggttcgccc caataacgct
     6841 ggcggctgaa aatagcgtcg cgcaagcggt agtttatctt cacacgtccc agatcgtgat
     6901 cttttacgta tttcttggta gcggctatcg cttccttgat cgtcagtccg ttcaaggaaa
     6961 gatcgcaata aggagtaacg ccggctctcg gagaattgca tacgatacct tccttggcat
     7021 cgaaactttc ctcgcttacg tcgcaacctt ccaccaaggg gcggatttcc agtccgaaat
     7081 gcttcgcgaa agcgtagtcg cggctatcgt gcgccggaac cgccatgatc gctcccgtac
     7141 cgtagccggc caatacatag tcgctgatcc agatgggaac cgcctcgccc gtaaacgggt
     7201 taatagcgta ggaaccactg aatacaccgg ttacctgacg gtcggcgatg cgctcgcgct
     7261 cggtacgttt cttggtgcga tctaggtaag cgtctacttc cgctttttgg tctgccgtag
     7321 ttaattgttg aaccaattcg ctttccggag ctaataccat gaaggtaaca ccaaacatcg
     7381 tatcggcacg ggtcgtaaag atcgtgaatt ccctgtcgct gtcttttacc ttgaagcgaa
     7441 cctcggcacc ttcgctgcgt ccgatccagt tcttttgggt ctctttcaag gaatccgtcc
     7501 agtcgatcgt atccaatccg tccaacaggc gttgtgcgta agcggataca cgtaagcacc
     7561 attggcgcat gatcttttgt tccaccggat agcctccacg ctcggaaaca ccgttcacga
     7621 cctcatcgtt cgctaatacg gtacccaagg cggcgcacca gtttaccatg gtctcgccac
     7681 gataagcgat ccggtagttg agtaatatct cttgtttttc tttatcgctc ttggctttcc
     7741 attcatcggc ggtgaaacta agttcctctc cgcaagctac gttcagacct tccgtaccac
     7801 tggtctcgaa agcctgtatc aactcgctga tcgggcgggc ttgcttctcg tcgttgcagt
     7861 agtagctgtt gaacatccgg atgaaggccc attgcgtcca tttgtaatat tcgggatcgc
     7921 aggtacggat ctcacggctc caatcgtagc agaaaccgat cttttccaat tgctcccgat
     7981 aacgggctat attattcttt gtcgtgatct ccggatgttg tccggtttgg atggcgtatt
     8041 gctcggcggg tagtccgtaa gcgtcgtaac ccatcgggtg caatacgtta aaaccttgca
     8101 aacgtttgaa acgcgaataa atatcagaag ctatataacc gagcgggtgg ccaacgtgca
     8161 atcccgcacc ggaaggatag gggaacatgt ccaatacata gtatttaggc ttattcgtgt
     8221 ccttttcgac tttataaacc ttttcggcaa tccagtagtc gtgccacttc ttctcaatct
     8281 ctctgaaatt gtactccatg atcgtttatc gtttttgtat cgttttctat ttaaggccac
     8341 aaagttagtg aatttattta ttttatatga gttatttaca tgaactgttt atttcacgta
     8401 accaatccgg gggcgagatt gattctcggt tcttttcgct tgtaactcag cgagtgacag
     8461 attgattagc tcaagttgcg tacgggtatc ttcgttgatg tcgttgtaat cggcaaatgc
     8521 ttcttcgata tacgctttga gttcctttac ttcttgttgg agttcaagca aaggggagga
     8581 agaacttatt atttgtcgta tgccgacgaa agcacgcatg atagagatat tgactttaat
     8641 ggctgtatcg gatctgagta cagaagaaag cattgctata ccttgctccg tgaaagcgaa
     8701 tggagcatat tggttacctc ctttctttga gatgccaatt tggcatacca tattgttttt
     8761 caagttgtta aattcttgaa ttgttaatgt gaacataaaa tcattaggaa agcgttctat
     8821 gtttcgtctg accgcacgtt tcaattgggc ggtttccgtt ccatacattt ccgccagatc
     8881 aaaatccagc atgacttttt gccctctgat ctcataaatc ttgttttgta tcgcttgtaa
     8941 ttccatagta taagaactta ttagtttact ttatttgata taaccaattt taggtctttt
     9001 agcattgttc tttttctttg tagccagttc ggaaagagct atgtaaatat catccaaaga
     9061 cttttgggta tcttcactga gatcattgat agcgcaaagc gtttcttcat tagccatttc
     9121 aagagatttg atacgttctt gtagctcttt aatttcgatg gaactagtgg tagcttgtaa
     9181 ggtataattc cgaatagcga caaagactct cataatgttt ctgttgattt ctatggcagt
     9241 tttagaattt agcacactac taagcatagc cacccctaat tccgtgaaag caaaaggctt
     9301 atatttgaaa ttactacctc ttcctttgtt caagatacca aattggcatc ttgaaagttc
     9361 ctccttggtt aactcaaaca tgaaatcatc tccttcaaag cgttctatat tacgtctgac
     9421 cgcacgtttc aattgggcag tttccgttcc atacatttcc gccagatcaa aatccagcat
     9481 gactttcata cctctgatct cgtgaatctt gttttgtatc gtttgtaatt ccatagtaaa
     9541 gattttagtt taatattatg gtcgcaaagg tttgtaaaat aattgagata agcaataagc
     9601 tagttggata ttaatgattg gttgcatttg taagttgtac aatgaattat tgctgatccg
     9661 gcttattgtc tattttttat gtgttcttat tttccttata agatttccgg gaaaaacacg
     9721 tacgtgattt atgaaaaaca cgtacgactt ttcggaaaaa catgtacgtg ttttccggaa
     9781 aacatgatga tgtttttata tcactgatat tcatgtatat ataacttgat acctttgcat
     9841 ggacttattg tgtgtttttt cttcttgtat ttgttatttt gttgttctat cgtttgttta
     9901 tgaattaaaa atatttaatt ttgcttatct ataataaagg atgaagtcat ttatatatat
     9961 actattaact tccttgactt tccttgtggt aggatgccaa aatgaatctg aggaaatccg
    10021 tttgatcaat caggcggaac gcctgtttga tgc
//
LOCUS       DBMDTB010000123         9950 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_1957_length_9950_cov_10.243883, whole genome shotgun sequence.
ACCESSION   DBMDTB010000123 DBMDTB010000000
VERSION     DBMDTB010000123.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 9950)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 9950)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9950
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1957_length_9950_cov_10.243883"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..290
                     /locus_tag="ACZPB4_14865"
     CDS             <1..290
                     /locus_tag="ACZPB4_14865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="carboxylase"
                     /protein_id="HIR1099534.1"
                     /translation="PMYSNPSNQFIALVKGEYGKTPIPVDPAFRLKITGVQNEVPYDG
                     SHYVMQENPVLEDLDVLLAENEKEILLLELFPTVARTFLTKWKEQKARSNV"
     gene            complement(433..864)
                     /gene="rpiB"
                     /locus_tag="ACZPB4_14870"
     CDS             complement(433..864)
                     /gene="rpiB"
                     /locus_tag="ACZPB4_14870"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase B"
                     /protein_id="HIR1099535.1"
                     /translation="MGIVGLCSDHAGFELKEYIKTILDERGLSYKDFGTYSSDSCDYP
                     DFAHLMGKAVEAGEVYPGIAVCGTGNGISMTLNKHRGVRAALCWREDIAKLAREHNDA
                     NVLSMPGRFISKEEAKKIVEIFLDTPFEGGRHQRRIDKIPL"
     gene            complement(867..2897)
                     /locus_tag="ACZPB4_14875"
     CDS             complement(867..2897)
                     /locus_tag="ACZPB4_14875"
                     /EC_number="2.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016744 - transketolase or transaldolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HIR1099536.1"
                     /translation="MNDIQVMNKAADNIRILAASMVEKANSGHPGGAMGGADFVNVLF
                     SEFLIYDPKNPKWEGRDRFFLDPGHMSPMLYSVLALSGKFTLDELQQFRQWGSVTPGH
                     PEVDVMRGIENTSGPLGQGHTYAVGAAIAAKFLKARLGEEVMNQTIYAYISDGGIQEE
                     ISQGAGRIAGTLGLDNLIMFYDANNVQLSTKVEDVDAENVAMKYEAWGWKVIQINGND
                     VNEIRKALKEAKAEISKPTLIIGNTVMGKGAVGADNSCYENKVSTHGQPLSAAGASIA
                     DTIKNLGGDPEHPFAILPEVAELYAKRTKELEVIVAERYAVKDVWAKAHPDLAAKMEQ
                     WFSGKAPKIDWAAIEQKANQATRAASATVLGVLATHVENMIVASADLSNSDKTDGFLK
                     KTHAFVKGDFSGAFFQAGVAELSMACICIGMSLHGGVIAACGTFFVFSDYMKPALRMA
                     ALMEQPVKFIWTHDAFRVGEDGPTHEPVEQEAQVRLLEKLKNHKGHNSMLVLRPADVV
                     ETTVAWKLAMENVYTPTALILSRQNITDLPAKENRYQEALQAEKGAYIVNEDANADVI
                     LLASGSEVSTLVEGAALLRADGIKVRIVSVPSEGLFRSQSKEYQESILPAGSKIFGLT
                     AGLPVNLEGLVGPNGKVWGLESFGFSAPYKVLDEKLGFTAKNVYNQVKELLA"
     gene            complement(3078..3770)
                     /locus_tag="ACZPB4_14880"
     CDS             complement(3078..3770)
                     /locus_tag="ACZPB4_14880"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HIR1099537.1"
                     /translation="MSAAFYQDEVKFYVAVDCIILGFNNKELNVLLYKRSFEPMKGQW
                     SLMGGFVKSGESVDEAASRVLTDCTGIEHLFMEQIGAYGDVSRDLGERVISVAYYSLV
                     NMNDFSPEILESHNATWTKISELPDLIFDHNQMINDTLSVLKKKAASRPIGFNLLPEQ
                     FTLPQLQTLYEAIYQTLLDKRNFRKKLNAMDILEKLDIKDKKSSKRGAFLYKFNEKKY
                     NKWVEQGFDFSL"
     gene            complement(3791..4936)
                     /gene="galK"
                     /locus_tag="ACZPB4_14885"
     CDS             complement(3791..4936)
                     /gene="galK"
                     /locus_tag="ACZPB4_14885"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004335 - galactokinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0046835 - carbohydrate phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HIR1099538.1"
                     /translation="MQQKIRTKFKELFNTEGSLYTSPGRINLIGEHTDYNGGFVFPGA
                     VDKGMIAEIKPNGTGKVRAFSIDLNDYAEFGLTEEDAPSASWARYIFGVCREIIKRGG
                     NIQGFDTVFAGDVPLGAGMSSSAALESTYAFALNDLFSLNIDKFELAKIGQATEHNYC
                     GVNCGIMDQFASVFGKAGSLIRLDCRSLEYKYYPFNPVGYKLVLLDSVVKHELASSAY
                     NKRRKSCENVVAAIRRNHPEVEFLRDATMEMLNEVKADVSAEDYMRAEYVIEEIQRVL
                     DVCAALEKGDYETVGEKMYGTHQGMSKLYEVSCEELDFLNDIAKECGVTGSRVMGGGF
                     GGCTINLVKDELYDDFVKKAFSAYKEKFGREPKLYNVVISDGARKLC"
     gene            complement(5044..6318)
                     /locus_tag="ACZPB4_14890"
     CDS             complement(5044..6318)
                     /locus_tag="ACZPB4_14890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HIR1099539.1"
                     /translation="MESTAKKNYTLPIIMMVALFFMISFVTGLQNPFGIIVKNQFAAS
                     NFMSQLGNAANFIAYAFMGIPAGMLLQKIGYKKTALLAIIVGFCGVGISYLSGVAGSY
                     AVYLTGAFVSGFSMCMLNTVVNPMLNTLGGGGNKGNQLIQVAGSVNSIGATIVPVLVG
                     YLIGDAAKAQISDANPALFLAMGIFAIVFIVLFCMQIPEPHMVKENEAKTPDKHSALS
                     FRHFILGAIAIFLYVGVEVGIPNFMNLFATSPEIGIDPTVAGSIVGTYWFLMMIGRLF
                     GASFGAKISSKAMLSSAATVGMIFILIAIFAPATTKVSMPVFLSDISFGMVEVPVGIM
                     FMALCGLCTSIMWGGIFNLAVEGLGKYTAAASGIFMVMVCGGGILPLIQGAVADAGGF
                     ITSFWVVFLGLAYLLYYALIGSKNVNKDIPVE"
     gene            complement(6364..7440)
                     /locus_tag="ACZPB4_14895"
     CDS             complement(6364..7440)
                     /locus_tag="ACZPB4_14895"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HIR1099540.1"
                     /translation="MKNINTLSGLSVANFSKQIDGKETALYTLCNKVGAELAITNYGA
                     KIVSLMVPDKNGKMTDVVTGHNSIEEYLTSEEPYFGAICGRYGNRIAAGKFTIDGITY
                     DKLAINNGPNSLHGGIKGFNAVVWDAKQIDEQTIELKYTSADGEEGFPGELKTTVTYH
                     LTNENEVVISYQASTDKPTVLNLTNHSYFNLSGAGDPYIGDHILTINADYYLPTDNTA
                     IPYGPKEKVEGTPMDFRTPHEVGERINDNFEQLIFGKGYDHTYILNKEDNELSYCARC
                     SSPKTGIVMETYTTQPGVQLYTGNWMTGNFEGKNGQRYPERAALCLETQHFPDSPNKP
                     EYPTTELRPGEVFQSTTIYKFSVE"
     gene            7711..>9950
                     /locus_tag="ACZPB4_14900"
     CDS             7711..>9950
                     /locus_tag="ACZPB4_14900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099541.1"
                     /translation="MPGLLYSQSQDWVRKSIYPQADSGKSKIYNWMWGRHYRHLYTIP
                     IRVPSATIETLGGGMDIVGQAEGFHGLLLENKRKQLYLLKPLGGSTSFLESKFFREIY
                     NKTDFKNTYLDEFLGDAYTIINPYTFLVADYLAKSAGLSFSPSRIYYIPSHIRKDTVA
                     DGSDIQDRLVNLINVPDINLRSNLYTTEDFLDSLQVSKNYMADQNLYIRERIFDMWTG
                     DWNKTNENWEWQSHTVNDSVIYTPIVIDRNHAFTKVDGVLFKQMLKMLSLDFICNYDS
                     LILKDTKKINKLAFALDMAVAGRSDESVWIRQAQEIQRQMTDSLIDSAFTYLPEGVKH
                     DEIELIKRKLKRRRLELEAVASQYYRLLQRTPVVAGTNQSDYFLIERQAPDRTVLRIY
                     DPETGDCRLEQQFSGKETKELWLYGLAGNDTFEVKGNTRKDFPIYLISGEGENQYQLN
                     HNRKIHVYDKDYKYDYQKIKYHKISFTPWGIYDSDKGISLGTFFTYTMYGFKRAPFTY
                     QHRIGYNYLKGFMYAGIFPNYDGRRRLYLNASISSPRNFENFFGFGNNTAGYKEEKKN
                     YNRVKLRTYMFNPSFEMDLRKEEVMTFFGSLDMYKAKRTDDRYIYTVYGEDHPIFRTN
                     YFVGLGATYRITKQPYSWLPLLETEWTAGWKMNLKKPERNFPYAQGSLSWNVRFSDRF
                     TWASLMKGTVLFDNDYEFYQAATIDLRGFRENRFIGKQSFYQYSDLRLDMGKLKNPFT
                     PLKYGL"
BASE COUNT         2747 a         2231 c         2162 g         2810 t
ORIGIN      
        1 gcccgatgta tagtaatcct tccaaccagt ttatcgcctt ggtaaaagga gagtatggca
       61 agacgccgat tccggtagat ccggcgtttc ggttgaaaat caccggcgta caaaatgagg
      121 tgccttacga cggttcccat tacgtgatgc aagagaatcc tgtattggag gatttggatg
      181 tgttattggc tgagaatgag aaagaaatac tgttgctgga gttattcccg acggtagccc
      241 gtacattttt aactaaatgg aaagaacaaa aagcgagatc gaatgtttaa tagtagaaag
      301 tcttcaaatt tggcatccgt catctattat atgtacgttg ccgtttaaac ggtgatacga
      361 aaaggctctc cgaatggtaa gcgaaccatg ggagagcctt ctttatttta taaagtgact
      421 ttttcgcgga ctttacaaag ggatcttgtc tatacgacgt tggtggcgac caccctcaaa
      481 aggtgtatcc aagaatatct caacgatttt cttagcctct tccttgctga taaaacgacc
      541 gggcattgat aacacgttcg cgtcgttatg ctcacgtgcc agtttcgcga tatcctctcg
      601 ccagcataag gcggcacgga caccccgatg tttgttcaag gtcatactaa tgccattccc
      661 tgtaccgcag acagctattc ccggataaac ctcgccagct tctacggcct tgcccatcag
      721 atgggcgaaa tccggataat cgcaactgtc agaggaataa gttccaaaat ctttataaga
      781 caatcccctt tcatcgagga ttgtctttat atattctttt aactcaaaac cagcgtgatc
      841 gctacacaaa cctactatac ccatctttat gctaataatt cttttacttg gttataaacg
      901 ttcttagccg tgaaacctaa tttctcgtcc aatactttgt aaggggcgga gaaaccgaag
      961 gattcaagtc cccatacctt gccgttagga cctaccaacc cttccagatt aaccggaaga
     1021 ccagcggtta agccgaaaat cttgcttcct gcgggaagaa tggattcttg gtattctttg
     1081 ctttgtgaac ggaatagacc ttcggaagga acggaaacga tacgaacctt tatgccatcg
     1141 gcacgaagca gggcggcgcc ctcgaccaaa gtcgatacct cggaaccgga agccaaaaga
     1201 attacatccg cgttagcgtc ttcattgacg atataggcac ccttttccgc ttgcaaagcc
     1261 tcttgatagc ggttttcctt agcgggaaga tctgtgatat tctgacggga aagaatcaat
     1321 gcggtaggag tgtaaacgtt ctccatcgct agtttccatg cgactgttgt ctccacaacg
     1381 tctgccggac gaagtaccaa catggagttg tgtcccttat gattcttcaa tttctctaat
     1441 aaacgaactt gagcttcttg ctctaccggc tcgtgtgtag gtccgtcttc tccaacacgg
     1501 aaagcgtcgt gtgtccagat gaacttaacg ggctgctcca tcaacgcggc catacgtaac
     1561 gcaggcttca tgtaatcgga gaatacgaag aatgtaccgc aagcggcgat cacgccacca
     1621 tgtaaagaca taccgataca gatacaagcc atagaaagct cggctacacc cgcttggaag
     1681 aaagctccgc taaagtcgcc tttcacgaaa gcatgggtct ttttcaagaa gccgtctgtc
     1741 ttatcggaat tggaaaggtc ggcggaagct acgatcatgt tttctacatg ggtagcaagc
     1801 acacctaata cggtagcgga agcggcacgg gtcgcttggt tcgctttctg ctcgattgcg
     1861 gcccagtcga ttttaggagc cttaccagag aaccattgct ccatcttagc cgctaagtcc
     1921 gggtgagctt tcgcccatac gtctttcacg gcgtaacgct cggcgacgat tacttccagt
     1981 tctttcgtgc gtttggcata taattcggct acctcaggaa ggattgcgaa cggatgttcc
     2041 ggatcgcctc ctaggttctt gatcgtatcc gcgatggaag ctcctgctgc ggataaaggt
     2101 tgtccgtgag tagatacctt attctcgtaa cagctgttat cagcgccgac agcacctttc
     2161 cccataacgg tgttaccgat gatcaaagtc ggtttggaga tctctgcctt agcctctttt
     2221 aaagccttgc ggatctcgtt tacgtcgtta ccgtttattt gaatgacttt ccagccccaa
     2281 gcctcgtatt tcatggctac gttctccgca tcgacgtctt ctaccttggt agatagctgc
     2341 acgttgttag cgtcgtagaa catgatcaag ttatccagtc ctaaagttcc ggcgatacgt
     2401 ccggcacctt gggagatttc ctcttggata cctccatcgg aaatatatgc gtaaatagtc
     2461 tggttcatta cttcctcacc cagacgtgct ttcaagaatt tagccgcgat agccgcacct
     2521 acagcataag tatgtccttg tcccaacggg ccggacgtgt tttcgatacc acgcataacg
     2581 tctacctcag gatgtcccgg agtaacgctt ccccattggc ggaactgttg aagttcatcc
     2641 aatgtgaatt tgccgcttaa agccagtacg gaataaagca tcggagacat atgccccggg
     2701 tcaaggaaga aacgatcgcg tccttcccat ttgggattct tgggatcgta tattaagaac
     2761 tctgagaaca gtacgttaac aaagtctgca ccacccatag cgccacccgg gtgcccggag
     2821 ttcgctttct ccaccattga cgcagccagt atacggatgt tatcagctgc tttgttcatt
     2881 acttgaatat cgttcatttt atcagatgaa ttatttattt gactgcaaag ataatcaaac
     2941 tctttgtaag agccgttata tcaatcaaac aattcctttt cggtaaaggt tcctatcttc
     3001 ttatattttt gataaattga gagatattta agatagcccg ctgagcgcct tattcttgcg
     3061 ggtatacatc attcggatta gagcgagaag tcgaaaccct gttcaaccca tttgttgtat
     3121 tttttctcgt tgaatttgta gaggaaagct cctcgtttag aacttttctt gtctttgata
     3181 tccagttttt ccagaatatc catggcgttt agctttttgc ggaagtttcg tttgtctaaa
     3241 agggtttggt agatggcctc atacaatgtc tgtagttggg gcaaggtaaa ttgctcggga
     3301 agcaaattga aaccgatagg gcggcttgcc gctttctttt taaggacgga caacgtatcg
     3361 tttatcattt ggttatggtc gaaaatcaag tcaggaagct cggatatctt ggtccaagta
     3421 gcgttatggc tttccaagat ctcggggcta aaatcattca tattcaccaa agaatagtaa
     3481 gctacggaga taactcgttc ccctaagtca cgtgatacat ctccgtaagc ccctatttgt
     3541 tccataaaaa gatgctcaat gcccgtgcaa tcggttaata cccgtgatgc tgcttcatcc
     3601 acgctttccc cggatttcac gaagcctccc ataagagacc actgtccttt catcggctcg
     3661 aacgaacgtt tgtataataa aacattcaac tccttattgt taaaccctag aatgatacaa
     3721 tctacggcaa catagaattt tacttcgtct tgataaaaag ctgctgacat cgttttatgg
     3781 attttaaaga ttaacagagc ttgcgtgctc cgtcgctgat tactacatta tataatttag
     3841 gttcacgtcc aaacttctct ttataagcgg agaaggcttt cttcacgaaa tcgtcgtaca
     3901 actcatcctt aaccaagttt atcgtacaac caccgaatcc tccacccatg acacgagaac
     3961 cggttacacc acattccttg gcgatatcgt tcaagaaatc cagttcctcg cagctaactt
     4021 cataaagctt gctcatacct tgatgcgtgc cgtacatctt ttcgccgaca gtctcatagt
     4081 cgcctttctc cagagcggca catacgtcga gtacacgttg gatttcctcg ataacatatt
     4141 cggcacgcat gtaatcctct gcgctgacat ccgcttttac ctcgttcagc atctccatcg
     4201 tagcgtcacg taagaactct acttccggat ggttgcggcg aatggcggct accacgttct
     4261 cgcaggattt acggcgtttg ttgtaggctg aggatgccaa ctcatgctta acgaccgaat
     4321 ccaataacac gagtttgtaa ccaaccggat taaacggata atatttatat tccaaagaac
     4381 ggcaatccaa gcggatcaaa cttccggcct tgccgaatac ggaagcgaat tggtccatga
     4441 taccgcaatt cacgccacaa taattatgtt ctgtagcctg accgatctta gccaactcga
     4501 atttatcgat attcaatgag aataagtcat tcaatgcgaa agcataagta ctttccaatg
     4561 cggcggaaga agacattcca gcgcccagag gcacgtctcc agcgaatacg gtatcgaaac
     4621 cttggatatt gccacctcgt ttaataatct cccggcatac gccaaagata tatcttgccc
     4681 agcttgcgga aggagcgtcc tcctcggtca agccaaattc agcgtaatca tttaagtcga
     4741 tggagaacgc ccggactttg cccgtcccat tcggtttgat ctcggcgatc atccctttat
     4801 ctacggcacc cggaaaaacg aaacctccat tataatcagt atgttcaccg atcaagttaa
     4861 tacgtcccgg agatgtgtat aagctacctt cggtattaaa taactcttta aatttagttc
     4921 tgattttttg ttgcatgata cttaatttga ttaaggtaaa taattgaata aacaagaaga
     4981 aattatccat tcagaaaact ctgccggata atttcttctt tattatatta tgtcctgtcc
     5041 ttattattca acaggaatat ctttgtttac gttcttgcta ccaatcaaag cgtaatatag
     5101 caaatatgcc aatcctagga ataccaccca gaagctggta atgaaaccgc cagcgtcggc
     5161 tacggctcct tggatcaacg gaagaatacc tccaccgcaa accatcacca tgaagatacc
     5221 ggaagcggct gccgtatatt tacctaaacc ttctactgcc aagttgaaga taccacccca
     5281 catgatggaa gtacataaac cacaaagagc catgaacatg attccaaccg gaacctcaac
     5341 cataccgaaa gagatatcag acaagaatac aggcatacta acttttgtcg tagcaggggc
     5401 gaagatagcg atcaagataa agatcatacc taccgtggcg gctgatgaca acatcgcctt
     5461 actagagatc ttagctccga aagaggcacc gaacagacgt ccgatcatca tcaagaacca
     5521 gtatgtaccc acgatagaac cggctactgt aggatcgata ccgatctcag gagaagtagc
     5581 gaacaagttc atgaagttag gaatacctac ttcgacaccc acatacaaga agattgcgat
     5641 ggcacctaaa atgaagtgac ggaaagaaag cgcgctgtgc ttgtccggag tcttggcttc
     5701 attttcctta accatatgcg gttccggaat ttgcatgcag aacaatacga taaatacgat
     5761 ggcaaagata cccatagcca agaacaatgc tgggttagcg tcactgatct gagccttagc
     5821 agcatcaccg atcaaataac caaccaatac cggaacgatc gtagcaccga tagagtttac
     5881 ggagccggca acctgaatta attggttacc tttgtttcca ccaccaccta gcgtgttcaa
     5941 catcgggttt actacggtat tcaacataca catagagaaa ccggacacga aagcacctgt
     6001 caaataaaca gcgtagctac cagccacacc ggaaagataa gaaataccta caccacagaa
     6061 acctacgatg atcgctaaca aagcggtttt cttgtaaccg atcttctgca atagcatacc
     6121 ggccggaata cccatgaagg cataggcgat aaagttagcc gcgttaccca gctgcgacat
     6181 gaagttgctg gcagcgaact ggttcttaac gatgataccg aatgggttct gtagacccgt
     6241 cacgaaagat atcatgaaga agagagccac catcatgata ataggcaatg tgtaattctt
     6301 ttttgctgtt gattccattt cttttttgtt gttttagatt attagattac ttaaattatt
     6361 ctcttattct acactgaatt tataaatagt agtactttgg aaaacctcgc ccgggcggag
     6421 ttccgttgtc ggatattccg gtttgttggg gctatcgggg aaatgctggg tttccagaca
     6481 taaagcggcc cgttccgggt agcgttgtcc gttcttacct tcgaaattcc cagtcatcca
     6541 gttacctgtg tataattgca cgcccggttg agtcgtataa gtttccatta cgataccggt
     6601 cttgggggag gagcagcgag cgcagtaaga aagttcgttg tcctctttat ttaatatgta
     6661 cgtgtggtca tatcccttac cgaatataag ctgttcgaaa ttgtcattga ttcgttcgcc
     6721 tacctcatga ggagtccgga agtccatcgg tgtaccttct accttctctt taggtccgta
     6781 cgggattgcc gtattgtctg taggcagata atagtcggcg ttgatcgtga gaatatggtc
     6841 tcctatataa gggtctcccg caccggatag gttaaaataa gaatgattgg ttagattcaa
     6901 gaccgtaggt ttgtccgtag aggcttgata ggagataacg acctcattct catttgtcag
     6961 atgataagtt acggttgtct ttagttctcc ggggaaacct tcctcgccat cggcggaggt
     7021 atatttcaac tcaatggttt gctcgtctat ttgtttggcg tcccatacga ccgcattgaa
     7081 tcccttgatt ccgccatgca agctattggg gccattattt atggctaatt tgtcataagt
     7141 aataccgtcg atcgtgaatt ttccagcggc gatacgattt ccataacgac cgcaaatggc
     7201 accgaaataa ggttcttctg atgttaagta ctcttcaatc gaattatggc cagtaacgac
     7261 atcggtcatt tttccgttct tatccggaac catcagtgag acgattttcg ctccataatt
     7321 cgtgatcgct agctctgctc caaccttgtt acacagggta taaagcgccg tttctttccc
     7381 gtcaatttgc ttgctgaagt tagcaacaga caagcccgac agtgtattta tgttcttcat
     7441 gcgtatcaat attattgaaa ttgcgtgtaa aagtaacttt cttctttgta tttataacct
     7501 ttctgaataa tgttttatag catgatttta gatttgtcta ccaaaaatat ataattatcg
     7561 cttgtttata cgtcaagtcc ttgattcttc tcttaggcta aaaaaacaaa acaactcttg
     7621 tcttacccct gttattagta aaacagagat agaaagaaat tgtccatgcg gtcgtcctat
     7681 aaatatatca tactcatact ctttgtgctt atgcccggct tgctttattc ccaatctcaa
     7741 gattgggtac gtaagtccat ttatccgcaa gcggatagtg gtaaaagcaa gatctataat
     7801 tggatgtggg ggaggcatta tcgtcacctt tatacgatcc cgatcagggt tccttcggct
     7861 acgatagaaa cgttgggggg tgggatggat atcgtcgggc aagcggaagg gtttcacgga
     7921 ttattgttgg agaataagcg taagcaattg tatttgctaa agcccttggg tggctctacg
     7981 agtttcttgg agtcgaagtt tttccgggaa atatataata agactgattt taagaataca
     8041 tatttggatg agttcttagg agatgcttat acgattatca atccctatac ctttttggtc
     8101 gcagattatt tagcgaagtc cgcgggattg agtttttctc cctcccgtat ttactatatt
     8161 ccttcccaca tacggaaaga cacagttgcg gacggcagcg atatacaaga taggctggtc
     8221 aatctaatca atgttccgga tattaattta aggtctaatt tgtataccac ggaagacttt
     8281 ctagacagcc ttcaagtgag taaaaactat atggcggatc aaaatctata cattcgggaa
     8341 cgtattttcg atatgtggac cggagattgg aataagacga acgaaaactg ggagtggcag
     8401 tcacataccg tcaatgatag cgtaatttat accccgatcg tgatcgatag gaatcatgct
     8461 ttcacgaagg tggacggagt attgttcaag caaatgttga agatgttatc gttggatttt
     8521 atctgtaatt atgatagcct gattttaaaa gatacaaaga aaatcaataa gctagctttt
     8581 gcgctggata tggcggtagc aggccgcagt gatgagtcgg tttggatacg ccaagcccaa
     8641 gaaattcaga gacagatgac cgactctttg atcgatagcg cttttactta tttgccggaa
     8701 ggtgtaaaac atgatgagat agaactgatt aaacgaaagt tgaaacgaag gaggctagag
     8761 ttggaagcgg ttgccagtca atattatcgc ttattgcaac gtacgccagt ggttgccgga
     8821 accaatcaat ccgattattt cttgatcgag cggcaagcgc cggaccggac tgttttacgg
     8881 atttatgatc ccgagaccgg agactgtagg ttggaacaac aattctccgg caaggaaacc
     8941 aaggaactgt ggttatatgg gcttgcggga aacgatacgt ttgaagtgaa gggaaataca
     9001 cggaaagatt ttccgatata cttgatctcc ggagaggggg agaaccaata ccaattgaat
     9061 cataaccgga aaatacatgt ctatgataaa gattataaat atgattacca gaagataaaa
     9121 taccataaga tatcttttac cccgtgggga atatatgatt cggataaagg tattagtttg
     9181 ggtacgttct ttacatatac gatgtatggc tttaaacgag ccccattcac ctatcagcat
     9241 cggatcgggt ataattattt gaaagggttc atgtatgcag gtatcttccc taattatgat
     9301 ggccggagac gtttatacct aaatgcctcc atttcttcac cccgtaactt cgagaacttc
     9361 ttcggatttg gaaataatac ggcgggctat aaagaggaga aaaagaatta taaccgggtg
     9421 aagctccgga cgtatatgtt taatccatcc ttcgagatgg atttgaggaa agaagaggtg
     9481 atgacattct ttggctcttt ggatatgtac aaggctaaac gtacggatga tcgatatatt
     9541 tatacggttt atggagaaga tcatcctatt ttccgcacga attatttcgt aggtcttggt
     9601 gctacttacc ggataacgaa acagccttat tcgtggcttc ccctattgga aaccgaatgg
     9661 acggccggat ggaaaatgaa tttgaaaaag ccggaacgta atttccccta tgcgcaggga
     9721 agcctttcat ggaacgtacg gttctcggat cgttttactt gggcctcctt gatgaaggga
     9781 acggtattat tcgataatga ctatgagttc tatcaagccg ccacgattga tttaagggga
     9841 ttccgtgaga accgttttat cggaaagcaa tccttttacc aatactcgga tttacgcttg
     9901 gacatgggaa aactaaagaa tccgttcact cccttaaaat atggtctatt
//
LOCUS       DBMDTB010000124         9830 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_1970_length_9830_cov_10.043992, whole genome shotgun sequence.
ACCESSION   DBMDTB010000124 DBMDTB010000000
VERSION     DBMDTB010000124.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 9830)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 9830)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9830
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1970_length_9830_cov_10.043992"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(99..455)
                     /locus_tag="ACZPB4_14905"
     CDS             complement(99..455)
                     /locus_tag="ACZPB4_14905"
                     /inference="COORDINATES: protein motif:HMM:NF019135.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component regulator propeller
                     domain-containing protein"
                     /protein_id="HIR1099542.1"
                     /translation="MENGLSQSSVKCVLVDERGVMWIGTRFGLNRFDREKITVYQEER
                     ENPHSLPYNDIVFLEEDAEGNIWVGTCCGLAYFDRGTFRNLLLSLLPVIFIFLEWKGW
                     LGYGPAMTFMRKRIFL"
     gene            783..1193
                     /locus_tag="ACZPB4_14910"
     CDS             783..1193
                     /locus_tag="ACZPB4_14910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011965854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 20 zincin-like fold
                     domain-containing protein"
                     /protein_id="HIR1099543.1"
                     /translation="MILVKCFLPDEKPEIIPFPLQSVSDKGDFTFNKATLISVENEKQ
                     AMIARELTDLFTLSAGFTPEIKIQDKRANIIFRTDRELAAEHYKLNIAPSCILIKASG
                     QKGFFYATQTLRFLLPPAINSPTQVEIFNGTYRE"
     gene            1298..1534
                     /locus_tag="ACZPB4_14915"
     CDS             1298..1534
                     /locus_tag="ACZPB4_14915"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099544.1"
                     /translation="MLKINRLHFTQEVHDTTPEGQQKMKDMNLYAKSKKITISNGTTH
                     THDIISYLPFQAELLIWKANISDCDEDKKGYSNI"
     gene            complement(1570..2214)
                     /locus_tag="ACZPB4_14920"
     CDS             complement(1570..2214)
                     /locus_tag="ACZPB4_14920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarC family protein"
                     /protein_id="HIR1099545.1"
                     /translation="MEDLLPFALLCFTSFFTLTNPLGTMPVFLTMTNGMNDHERKAIV
                     RRATIVSFITLMVFTFSGQFLFKFFGISSNGFRIAGGFIIFKIGFDMLQARYSNAKLK
                     EEEVKTYADDISITPLAIPMLCGPGAIANAIMLMDDASTLSLKGTLIGIIALVYFITF
                     LILQASTRLVRILGETGNNVMMRLMGLILMVIAVECFVSGLKPILIDILREAMG"
     gene            complement(2309..3556)
                     /locus_tag="ACZPB4_14925"
     CDS             complement(2309..3556)
                     /locus_tag="ACZPB4_14925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PNGase F N-terminal domain-containing protein"
                     /protein_id="HIR1099546.1"
                     /translation="MIKKLVLFVSLTGVFLCTASCGHKELPSMGDYSVQVFNDTHVRF
                     APDVYPAAFNAPGPDSIYHLVNGRIILKKVTLPEYKRNVSVKLRVTVASNGDRWDKSG
                     SCFVLPNASGINLLNIAKGEKEFPAVDSVKLEKMIGIIPGTDYQPTVELMRFMTPFGV
                     GHYSSPEDSLTKHRKPVYVDHWEDSVSWEQDITDLYPLLEGGAYVGIFIDTWTPEGYV
                     ASMTIDVDESDLTCDALPKKHVEPLMNTVYYIGQEYPDIFARKDVSLDFDIPQGARDV
                     RLKYIVTGHGGHSGGDEFVEKQNIVSVDGVPVLDFVPWRTDCASFRRFNPATGVWLRK
                     RLAAYITEKGYSEKEVEEPLASSDLSRSNWCPGSDVIPEEVELKDIQPGHHTLTVSIP
                     EAAEVDGNKLNHWLVSAYLVWDE"
     gene            complement(3562..4998)
                     /locus_tag="ACZPB4_14930"
     CDS             complement(3562..4998)
                     /locus_tag="ACZPB4_14930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007654143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monomeric [FeFe] hydrogenase"
                     /protein_id="HIR1099547.1"
                     /translation="MAFTNNVMIVRHGLLAKLVKLWKENRLLEEIDRLPIELSPRKSK
                     VRGRCCVHKERAVWKYKTLPLLGFDMQDEEDELTPLSEYAKRALFRSENKKENIMCVV
                     DEACSSCVSVNYEITNLCRGCVARSCYMNCPKDAIRFKKNGQAEIDHETCISCGKCHQ
                     SCPYHAIVYIPIPCEEVCPVKAISKDEYGVEHIDESKCIYCGKCVNACPFGAIFEISQ
                     VFDILQRLRNKEQMVAIVAPSILAQFSAPKEKVYGAIKSLGFEEVVEVAQGAMETTRH
                     EAEELIEKLKEGQPFMTTSCCPSYVQLAEKHIPDLKKYISSTGSPMYYTARIVKEKYP
                     DAKIVFVGPCVAKRKEVKLDPCVDFTLTFEEVGSVLEGLGIKIEEAQPFSVLFNAVRE
                     AHGFAQSGGVINAVKVYLKDENVNAVQVANLTKKNVALLRAYAKTGKAPAQFIEVMAC
                     EGGCVTGPCTHADKTAGQKQLIKELTKF"
     gene            complement(5076..5444)
                     /gene="folB"
                     /locus_tag="ACZPB4_14935"
     CDS             complement(5076..5444)
                     /gene="folB"
                     /locus_tag="ACZPB4_14935"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004150 - dihydroneopterin aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006760 - folic acid-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HIR1099548.1"
                     /translation="MTTKIELRRMTFYAYHGVAPQETRVGNTFIVDLILTAPLENAVW
                     SDDLSDTINYATVYETVKAEMAIPSRLLEHAAGRILKALKERFPQITEVELVLSKLNP
                     PFGGDIHSASIILKESFLSV"
     gene            5536..5907
                     /locus_tag="ACZPB4_14940"
     CDS             5536..5907
                     /locus_tag="ACZPB4_14940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bactofilin family protein"
                     /protein_id="HIR1099549.1"
                     /translation="MGIKQKDENSAGGLHNALAAGTTIKGNIITETDFRLDGKVEGDI
                     SCNGKIVIGPKGSVTGNIVSENAEILGEVDGSVKVSAKLILKSTAIIKGDIYTQSLEI
                     EPNARFNGACSMCSEKKKADK"
     gene            complement(5947..8634)
                     /locus_tag="ACZPB4_14945"
     CDS             complement(5947..8634)
                     /locus_tag="ACZPB4_14945"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004134 - 4-alpha-glucanotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HIR1099550.1"
                     /translation="MKVTFNINFHTVWGQKLCVVGSIPELGSWEPALAKEMNYSGDGN
                     WKLELDLPPDIKDIEYRYFLSVNDKQIFEEWEKNHRIVLDGQSDSYILYDYWQIRPDN
                     LAFYSSAFTKSLFAHPCNTHERVVRSGRKLVIKISAPRVEKNQCVAITGNQECLGNWH
                     PDKALLLSCDTFPEWHIDLDAAEIRYPLEYKFLVWDNDSRQPLYWESDENRILSLVPQ
                     KQGETVVISGLYFRDSLPLWRCAGSVIPVFSLRSEKSFGVGDLGDLHMLVDWARKTHQ
                     RIIQVLPMNDTTMTHTWVDSYPYSAISIYALHPMYVDLSALGTLKDPERAAFYAGKQK
                     ELNAKDTVDYEEVLKYKLGYCQEYFAGEGKAVLDTPEFKEFLAQNESWLMPYATYCFL
                     RESYGTSDFSQWQGNSTYNKTRVRTLCREDSDAWPEISFSYFLQYVLHNQFKSVSDYA
                     RKNGVVLKGDLPIGVSRTSVEAWTEPKYFNMNGQAGAPPDDFSMNGQNWLFPTYNWDA
                     MEKDNFSWWKKRFAKLSDYFDCFRIDHILGFFRIWEVPCEYVQGLCGHFNPALPFSRE
                     EIEQYGLNFNESRFTTPHINRQFLSELFEENTEEVIGAYLAQSSSRHYVLKPFCDTQR
                     KIEALFADKADPVSLRIKNGLFTIANEVLFLRDPRETDKFHPRISANQSYIYRELSGS
                     DRYAFDQLYWHFFYHRHNDFWKAQAFKRLTPLVASTEMLVCGEDLGMIPASVPEVMNK
                     LQILSLEIERMPKSPQREFSDMFNLPYHSVCTTSTHDMTPLRNWWKEDPEKTQRYYNH
                     VLQRIGEAPDECTAEIVAQIISNHLKTRSMLTIIPLQDWFAMDDSIKRKDIESERINV
                     PANSTHYWRYRMHITLEQLLQADNLNNKIVSLIKEAGRK"
     gene            complement(8658..>9830)
                     /locus_tag="ACZPB4_14950"
     CDS             complement(8658..>9830)
                     /locus_tag="ACZPB4_14950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008769973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobalamin-dependent
                     ribonucleoside-diphosphate reductase"
                     /protein_id="HIR1099551.1"
                     /translation="NPFINRLREADPALYEDMLKYGRRNIACLTIAPTGTTSLMTQTT
                     SGIEPVFLPVYKRRRKVNPNDSEARVDFVDETGDAFEEYIVFHHKFVTWMQANGYSAS
                     KKYTQEEVEELVAKSPYYKATSNDVDWLQKVRMQGRIQKWVDHSISVTINLPNDVSEE
                     LVDSLYVEAWRCGCKGCTVYRDGSRSGVLIATDKKKKKEDCNCMQPPVIVSTRPRELD
                     ADVVKFQNNREKWIAFVGLLNGRPYEIFTGLADDDEGIMLPKNVSKGTIIKSYDEDGN
                     KHYDFQFKNKRGYKMTIEGLDGKFNPEYWNYAKLISGVLRYGMPIDQVIKLVQGMELN
                     SESINTWKNGVERALKKYLPNGMEAKGQKCPNCGLETLIYQEGCLICTNCGASKCG"
BASE COUNT         2945 a         2471 c         1845 g         2569 t
ORIGIN      
        1 cccaagggaa acataatccc acggaatgga aatagcctgt tccccggata taccatcagg
       61 atgaatcggt aacccatcta aagccaaatt aatcatgctc acagaaaaat cctcttcctc
      121 atgaatgtca tagccgggcc gtatcctaac cagcccttcc actccagaaa tataaatatt
      181 accggaagaa gactcaaaag caggttccgg aaagtaccac gatcgaaata tgccaatccg
      241 caacaggttc ctacccaaat atttccctcc gcatcttcct ccaaaaaaac tatatcatta
      301 taaggaagag aatgcggatt ctccctctcc tcctgataaa cggtaatctt ttccctatcg
      361 aaacgattca acccaaatcg ggtaccaatc cacataaccc ctctttcatc taccagcaca
      421 cattttacgg aagactgcga taatccgttt tccaaagaga tttgtttaaa ataataccta
      481 ggagctgcat aaagagactc tgttaaacac actaaaaaca gcaatagata taattgtaaa
      541 aacttccaaa atactcgcat agttgtatat cacccattgt tcggcaaaaa cactaaatcg
      601 tccgaaatat aaggcttgca gagtataaaa aacgtttttt gaattttcac ggacgatttt
      661 ggactcaaga aaatatcctt aaagcataga tttgcagcaa gtgaaaaatt aaacaaaaaa
      721 gcatatcatt aaaaattatt cttatgttac gtacaacggg tatatatttt attattttgg
      781 ttatgatact tgtaaaatgt ttccttccgg acgaaaaacc ggagatcatt cctttcccct
      841 tgcaaagtgt atcagacaaa ggtgatttca cattcaacaa ggcaaccctc atcagtgtag
      901 aaaatgaaaa acaggctatg atcgctcggg agttgaccga tctgttcacg ctttccgccg
      961 gattcacccc ggaaataaaa atacaagaca aacgagccaa tatcatattc cgcacagaca
     1021 gagaactagc ggccgaacat tataaactga atatagcccc ctcttgtatt ctaataaaag
     1081 catccggaca aaaaggtttc ttttacgcaa cgcaaacctt acgttttctg cttcctccag
     1141 caataaacag cccaactcag gtagagatat tcaatggaac gtaccgggaa tgaccatact
     1201 agatggcccc cgatacagca atcggaccgt ggcaatacac acacctttca ctctcatctc
     1261 gaaggataat ctcaaagaat taatcgatca cctagccatg ttaaaaataa acagacttca
     1321 tttcacacaa gaagttcatg atacgacacc tgaaggacag caaaaaatga aggatatgaa
     1381 cctgtatgct aaatccaaga agatcacgat ctcaaacgga acaacacaca cccatgatat
     1441 catatcgtat ctcccgttcc aagcagagct acttatctgg aaagcaaata tctccgattg
     1501 cgatgaggat aaaaaaggtt attccaatat ttagcgccca tcgcagaaag aagctggtct
     1561 ggtaatttgt tagcccatcg cctcacgcaa gatatcgatc aagataggct tcaatccgct
     1621 tacgaaacat tccacggcga tcaccatcag tatcaatccc atcaaacgca tcatcacgtt
     1681 atttccagtc tctcccaata tccgtaccaa acgggtagaa gcttgtaaga tcaagaacgt
     1741 gataaaataa accaatgcga taataccaat caacgtaccc tttaagctga gtgtcgaggc
     1801 gtcatccata agcatgattg cgttggcgat cgctcccgga ccgcacaaca tcgggattgc
     1861 cagaggagta atggatatat catccgcata ggttttcacc tcttcctctt tcaacttcgc
     1921 gttcgagtag cgtgcttgaa gcatatcaaa cccaatcttg aagataataa agccgccagc
     1981 tatgcgaaag ccgttcgagg agataccaaa gaacttaaac aggaactgac cggagaaagt
     2041 aaaaaccatc aaggtgatga acgacacgat cgtggccctt cggacaatcg ctttccgctc
     2101 atggtcattc ataccattgg tcatggtcaa gaaaaccggc atcgtaccga gtggattggt
     2161 caacgtaaaa aacgaagtga aacataatag ggcgaaaggt aacaagtctt ccatatcaat
     2221 aattttttaa ttggctaatg tgccaatatg ccaattagtt gaagagagca tgattggcac
     2281 attggtacat aacatattat cacattattt actcatccca gaccaaatag gctgagacca
     2341 accaatgatt cagcttattc ccatccactt ctgccgcttc cggaatactc accgtcagcg
     2401 tatgatggcc gggttggata tccttcagct ccacctcttc cggtatcacg tccgatccgg
     2461 gacaccaatt agagcgggaa agatccgaag acgccaaggg ttcctctact tctttctccg
     2521 aataaccctt ctcggtgata taggcagcca gacgctttct caaccaaacc ccggtagccg
     2581 gattaaaacg acggaaagaa gcgcagtccg tacgccaagg aacaaaatcc aagacaggaa
     2641 ctccatcaac agatacaata ttctgtttct ccacgaactc atcaccaccg gaatgaccgc
     2701 catgtcccgt aacgatatat ttcagacgga catcacgtgc gccttgagga atatcaaaat
     2761 ccaatgacac gtccttccgg gcgaatatat ccggatattc ctgcccgata taataaaccg
     2821 tattcatcaa cggctctaca tgtttcttcg gcaaagcgtc gcaagtcaga tcggactcgt
     2881 ccacatcgat cgtcatgcta gcgacgtatc cttccggtgt ccatgtatcg ataaagatcc
     2941 caacataagc gccaccttcc agaagaggat acaaatcggt tatgtcttgc tcccagctta
     3001 cgctatcctc ccaatggtcg acatacacag gtttacgatg tttcgtcaag ctatcctcgg
     3061 gactactgta atgccctact ccgaacggag tcatgaaacg catcaattcc acggtaggtt
     3121 gataatccgt cccggggatg ataccgatca tcttctccag tttcacgcta tccaccgcag
     3181 gaaactcctt ctccccttta gcgatattca acaaattaat gcccgaggca tttggcaata
     3241 caaaacaaga gccggattta tcccagcgat ctccattcga agctaccgta acccggagtt
     3301 tgacggaaac gtttcgctta tattccggca atgttacctt cttcaagata atacggccat
     3361 tcaccaaatg atagatactg tccggtcccg gagcgttaaa agcggcggga tatacatccg
     3421 gagcgaaacg tacgtgggta tcattaaata cctgtacgga ataatctccc attgacggta
     3481 attctttatg tccgcaagaa gcggtacata gaaaaactcc cgtcaaggag acaaataaaa
     3541 ccaatttttt aatcattttg tctagaattt agtaagctcc ttaataagct gcttttgtcc
     3601 ggcagtctta tcggcgtgcg tacaaggacc ggtcacacaa ccgccctcgc aagccatcac
     3661 ttctataaac tgcgcgggag cctttccggt tttagcataa gcacgtaata atgccacatt
     3721 tttctttgtc aggttggcta cctgcacggc atttacgttc tcgtccttca aataaacctt
     3781 aacggcgttg atcacaccac cactttgggc gaagccatgc gcctcacgga cagcgttaaa
     3841 taatacagag aaaggctggg cctcctcgat cttgataccc aatccctcca atacggaacc
     3901 tacttcctca aacgtaagtg taaaatccac gcacggatct agtttcacct cttttcgttt
     3961 cgccacgcac gggccaacaa acacgatctt cgcatccgga tatttttcct tcacgatacg
     4021 ggccgtataa tacatcggag atccagtaga agagatgtat ttctttaaat ccgggatatg
     4081 tttctcggcc aattgcacgt aagacggaca gcaactagtg gtcatgaacg gttgtccttc
     4141 tttcaatttc tcgatcaatt cttccgcctc atgacgggtg gtttccatag cgccttgcgc
     4201 cacctcaacc acttcctcga atcccaagga cttgatagcg ccatacactt tttccttcgg
     4261 agcgctaaac tgagctaaga tagacggagc gacaatcgct accatctgtt ccttattccg
     4321 caagcgttgc aagatatcga atacttgcga gatctcgaag atagcaccga acggacaagc
     4381 attcacacat ttaccgcaat atatacattt agactcgtcg atatgctcca ccccatactc
     4441 gtccttgctg atcgccttaa ccggacaaac ttcctcgcaa gggatcggga tataaacgat
     4501 ggcatggtac ggacagcttt ggtggcattt accacagctg atacaagttt catgatcaat
     4561 ctcggcctga ccgtttttct tgaatcggat agcgtccttc gggcagttca tataacaact
     4621 acgagccacg caaccccggc aaagattcgt gatctcataa ttcacggaga cacaagagga
     4681 acacgcctca tccactacac acatgatatt ttccttctta ttctccgagc ggaacaaggc
     4741 acgcttcgca tactctgaaa gcggtgtcaa ctcatcttcc tcgtcctgca tatcaaaacc
     4801 aagcaaaggc aaggtcttgt atttccagac ggcacgttcc ttatgtacac agcaacggcc
     4861 cctcactttc gattttcggg gactcaactc gatcggtaag cgatctattt cttctagaag
     4921 acggttttct ttccagagct ttactaactt cgccagcaat ccgtgacgaa caatcattac
     4981 gttgttggta aatgccataa tgttatcgta tttgtgcttt tagtatatcg tatatcgcat
     5041 cacttcttta caaacgcgaa ggtaaataaa agtttctaaa cagaaagaaa gctttcttta
     5101 agaattatcg aagcactatg aatatctccg ccaaacggag gatttaattt agacaagaca
     5161 agttccacct ccgtgatctg tggaaatctc tctttcaaag ccttcaagat acgccccgcc
     5221 gcgtgctcaa gaagtctcga ggggatagcc atttctgctt tcacggtttc atatactgtg
     5281 gcgtaattga tcgtatcgct taaatcgtcg ctccataccg cattctccaa cggcgctgtc
     5341 agtatcaaat ctacgataaa agtattccca acccgggtct cttggggtgc cacgccatga
     5401 taggcataga atgtcatcct tcgtaattca atctttgttg tcataatctt ttaatttatc
     5461 tgtaaatgta tagaaagtaa accttcctgc aaaaaaatag tcttatattt gtcaaccaag
     5521 taacaacaca ttatgatggg aataaaacaa aaagatgaaa attccgcagg cggattacac
     5581 aacgccttgg ctgcggggac aacgataaag ggtaatatta tcacagagac agactttcgc
     5641 ttggatggaa aagtagaagg ggacatcagt tgcaacggca agatcgttat cggccccaaa
     5701 ggtagcgtaa caggcaatat cgtatccgag aatgctgaga ttctcggtga ggtagatggc
     5761 tccgtaaaag taagcgcaaa gcttattcta aaatcaacag caattatcaa gggagatata
     5821 tatacccaat ccctagagat cgaaccaaac gcacggttca acggagcctg ctcgatgtgt
     5881 tccgagaaaa agaaagcgga caaatagact gagggccgca cttttcgata cggcccttag
     5941 tctttcttat tttcgtccag cctcttttat caacgagact atcttattat tcaggttatc
     6001 agcctgcaaa agctgttcca acgtaatatg catccggtag cgccaataat gcgttgaatt
     6061 cgcaggaacg ttaatacgct cggattctat atcctttcgc ttgatagaat catccatagc
     6121 aaaccaatcc tgcaacggaa taatcgtcag catggaacga gtcttcaaat gattagaaat
     6181 aatctgggca acgatttcag ccgtacattc atccggggcc tcaccgatcc gttgcaatac
     6241 atggttgtaa taacgctgtg tcttctccgg atcttctttc caccaattac gaagaggagt
     6301 catatcatgt gtagaagtcg tacaaacgga atgataaggc aaattaaaca tatcggaaaa
     6361 ttcccgctgc ggactcttcg gcatacgctc aatctcaagg cttagtattt gcaacttatt
     6421 cataacctcg ggaacagagg cggggatcat acctagatcc tctccacaaa ccaacatctc
     6481 cgtggacgcg accaacggtg tcaaacgctt aaacgcttgc gccttccaaa aatcattatg
     6541 gcgatgatag aagaaatgcc agtataactg atcgaacgca taacggtcgg aaccactcaa
     6601 ttcccgatag atataggatt gattcgccga gatccgggga tggaacttat cggtctctct
     6661 tgggtcacga agaaataata cctcattcgc aatcgtaaac aggccattct tgatccgtag
     6721 ggaaactgga tccgccttat ccgcaaacaa cgcctcaatc ttcctttgcg tatcacagaa
     6781 cggttttaac acataatgcc gggaggagga ttgtgccaaa taagcaccta tcacctcttc
     6841 tgtattttcc tcaaacaatt ccgataaaaa ttgtcgattg atatgtgggg tcgtgaaacg
     6901 agattcgtta aaattcaatc catactgctc gatctcttct ctcgagaacg gcaacgctgg
     6961 attgaaatga ccacaaagcc cttgcacata ttcacaagga acctcccata ttcggaaaaa
     7021 tcccaagatg tgatctatac ggaaacaatc gaaataatca cttaacttag cgaagcgttt
     7081 tttccaccaa gagaaattat ctttctccat cgcatcccag ttataagtcg ggaacagcca
     7141 gttctgaccg ttcatggaaa agtcatcggg gggagcaccc gcttgaccat tcatattaaa
     7201 atatttcggt tccgtccaag cctctacact agtgcggctc acgccaatgg gtaaatcacc
     7261 tttcaataca actccattct tacgggcata atccgatacc gacttgaact ggttgtgcaa
     7321 tacatattgc aagaaataag agaacgagat ctccggccat gcgtcactat cttcccggca
     7381 tagggtgcga acacgtgtct tattgtaagt agaattacct tgccattgag agaaatccga
     7441 tgtcccataa ctttcccgca agaaacaata agtagcgtaa ggcatcaacc atgactcatt
     7501 ttgcgccaag aactctttaa actccggcgt atctaatacg gccttaccct cccctgcgaa
     7561 atattcttga caataaccca atttatattt cagtacttcc tcgtaatcaa ccgtatcttt
     7621 tgcgtttaat tctttttgct tccctgcata aaaagcagct ctctccggat ctttcaaggt
     7681 ccccaaagcc gataaatcca catacatggg atgaagggca taaatagaaa tagcgctata
     7741 cggataggaa tccacccaag tatgggtcat tgtcgtatca ttcataggta atacttgaat
     7801 gatacgttgg tgcgtctttc tagcccaatc caccaacatg tgtaaatctc ccaaatcacc
     7861 tactccaaag ctcttttccg agcgcaagga aaagacgggg ataaccgagc cggcacaacg
     7921 ccataacggt aagctatccc ggaagtaaag accagatata acaacggtct caccctgttt
     7981 ctggggaaca agacttagaa tacgattctc atcactctcc caatacaaag gttgacggga
     8041 atcattatcc caaaccaaaa atttatattc taaaggatac cgtatctccg cagcgtctaa
     8101 atcaatatgc cattccggga aagtatcgca actcagcaat aaagccttgt ccggatgcca
     8161 gttacctaag cattcttgat ttccagtaat ggctacacac tgattctttt ccacccgggg
     8221 agcggatatc tttatcacca attttcttcc acttctaacg accctctcat gtgtattgca
     8281 gggatgagcg aataaacttt tggtgaaagc cgaagaataa aaggctagat tatccggacg
     8341 gatttgccaa taatcataaa ggatgtaaga atcagattgt ccatccaata caatccggtg
     8401 attcttctcc cactcctcaa agatctgctt atcattaaca cttaagaaat atctatattc
     8461 tatatctttt atatcgggtg gaagatccag ttccagtttc cagtttccat ccccagagta
     8521 attcatctcc ttagccaaag caggttccca agagcctaat tccggtatgg agcccactac
     8581 acataacttc tgtccccaaa cggtatggaa gtttatatta aaagtgactt tcatggtata
     8641 tagatttagt caattattta accgcattta gaggctccgc aattcgtgca gatcaaacaa
     8701 ccttcttgat aaatcaaggt ctccaaccca cagttcggac atttctgccc tttcgcttcc
     8761 atgccgttcg gtaaatattt cttcaaggcc cgttccacgc cattcttcca agtattgata
     8821 gactcgctat tcaactccat accctgtacc agttttataa cctgatcgat aggcattccg
     8881 taacggagca caccggaaat caatttagcg tagttccaat attccggatt aaacttgcca
     8941 tccaagcctt cgattgtcat tttataaccg cgtttattct tgaactggaa gtcgtaatgc
     9001 ttattaccat cctcatcata gctcttgatg atcgtacctt tagaaacgtt tttaggtaac
     9061 atgataccct cgtcatcatc ggccaaaccg gtaaagatct catacggacg gccattcaac
     9121 aagccgacga aagcgatcca tttctcacgg ttattctgga attttaccac atccgcatcc
     9181 aattcacgag gacgggtaga tacgataacc ggtggttgca tgcagttgca atcctctttt
     9241 ttcttctttt tatctgtcgc aatcaagaca ccggaacgag aaccatctcg ataaacagta
     9301 catcctttac atccgcatct ccatgcctca acatacaaag agtctaccaa ctcctcactt
     9361 acatcgttcg gcaaattgat cgttacgctg atagaatggt ccacccattt ctgaatgcgt
     9421 ccttgcatac ggactttttg taaccaatcg acatcattgg aagtcgcttt ataataagga
     9481 gacttagcaa ctagctcctc cacttcttct tgtgtatatt tcttacttgc cgaataacca
     9541 ttcgcttgca tccacgttac aaacttatga tggaatacga tatactcctc gaaagcgtcg
     9601 cctgtctcat ccacgaaatc cacacgagcc tcggaatcgt tcgggtttac tttgcggcgg
     9661 cgcttatata ccggcaagaa taccggctct ataccggaag tggtctgtgt catcaagcta
     9721 gtcgttcccg tcggagcgat tgttaagcaa gcgatattac gacggccgta tttcaacata
     9781 tcctcatata aagcaggatc agcctcacgc aaacggttga tgaacggatt
//
LOCUS       DBMDTB010000125         9759 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_1982_length_9759_cov_8.330814, whole genome shotgun sequence.
ACCESSION   DBMDTB010000125 DBMDTB010000000
VERSION     DBMDTB010000125.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 9759)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 9759)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9759
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1982_length_9759_cov_8.330814"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..714
                     /locus_tag="ACZPB4_14955"
     CDS             <1..714
                     /locus_tag="ACZPB4_14955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HIR1099552.1"
                     /translation="LIIHGMNGKPITARTENQQLLVKAFENNDLVFATGPAGSGKTFV
                     AIALAVKALKNKEVRKIILSRPAVEAGEKLGFLPGEMKDKLDPYLQPLYDALQDMIPA
                     AKLKEYMENNVIQIAPLAFMRGRTLNDAVIILDEAQNTTTHQIKMFLTRLGMNAKMIV
                     TGDVTQIDLPPSTTSGLIQAMQILKGVNGIGKIEFTKKDIVRHKLVQRIVEAYDKFDD
                     KRKKEIKEAKEKKTNIDNN"
     gene            726..1676
                     /locus_tag="ACZPB4_14960"
     CDS             726..1676
                     /locus_tag="ACZPB4_14960"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HIR1099553.1"
                     /translation="MKKALVKTDFNFPRQKSVYHGKVRDVYNINDEVLVMVATDRISA
                     FDVILPEGIPYKGQMLNQIAAKFLDATTDICPNWKMATPDPMVTVGVQCQGFPVEMIV
                     RGYLCGSAWRAYKSGVREICGVKLPEGMRENQRFPEPIITPTTKAEIGEHDQDISKEE
                     ILAKGLVSKEDYEVLEKYTMALFKRGTEIAKERGLILVDTKYEFGHRDGKIYLIDEIH
                     TPDSSRYFYSEGYEDRFAKGEPQKQLSKEFVREWLMENGFQGKSGQKVPEMTPEIVEG
                     ISNRYIELFEHITGETFVKGETDNLLNRIEKNVTEYLQNK"
     gene            1687..2430
                     /gene="ubiE"
                     /locus_tag="ACZPB4_14965"
     CDS             1687..2430
                     /gene="ubiE"
                     /locus_tag="ACZPB4_14965"
                     /EC_number="2.1.1.163"
                     /EC_number="2.1.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052624 - 2-phytyl-1,4-naphthoquinone
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0042372 - phylloquinone biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional demethylmenaquinone
                     methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol
                     methylase UbiE"
                     /protein_id="HIR1099554.1"
                     /translation="MTQYGSETILPYNKEEQKGTQVKRMFDSIAETYDQLNHTLSFGI
                     DKIWRRKGIAFLRPFSPKTILDIATGTGDLAISMYKKLRPDHIVGADISLGMMEVGRK
                     KVAAAGYSEHISFEQQDCTALTYEENSFDAVTAAFGVRNFENIEQGISEMYRVLKPGG
                     HIMILELSTPEHFPMRQLYQIYSKTVIPFIGRLLSKEKVAYNYLPASIKVVPQGKIMT
                     DLLTRQGFKQARVRTFTFGICSLYTGSKE"
     gene            2445..3188
                     /locus_tag="ACZPB4_14970"
     CDS             2445..3188
                     /locus_tag="ACZPB4_14970"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016272587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase family protein"
                     /protein_id="HIR1099555.1"
                     /translation="MQKYGLLGYPLGHSFSKTYFNQKFEAEKIDAEYLNFEIPSIKEI
                     KNVIKENPELNGLNVTIPYKEQVIPYLDDLDDDARQIGAVNVIKFTKGLFGKLKLKGY
                     NSDIIGFKQSIDPLLKETHRKALILGTGGASKAVFHGLKQLGVGATLVSRKPKEFCIT
                     YDEITPKTMEQYTVIVNTTPLGMFPNIDSCPDIPYDLLTPNHLLYDLLYNPDETLFMK
                     KGKEKGAVVKNGLEMLLLQAFAAWEIWQK"
     gene            complement(3298..3915)
                     /locus_tag="ACZPB4_14975"
     CDS             complement(3298..3915)
                     /locus_tag="ACZPB4_14975"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase family
                     protein"
                     /protein_id="HIR1099556.1"
                     /translation="MALLYKQLSPLHGVWKMEESSDELLGMLEHKADYSSFLERVSAE
                     KRRQERFASRVLLKELLGEEARVDYHSTGAPFLACVPLYISISHTKDYVAVILDKRPT
                     GIDIEYRSDRILKIRSRFMNPEEEAGIDLEHEVEHLLIHWCAKETLFKIIGQEGVDFQ
                     KHLHVNPFPYLSSGTFKGRETRTEACREYELAYQVTPDYVLTWLK"
     gene            complement(3917..4498)
                     /gene="gldD"
                     /locus_tag="ACZPB4_14980"
     CDS             complement(3917..4498)
                     /gene="gldD"
                     /locus_tag="ACZPB4_14980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gliding motility lipoprotein GldD"
                     /protein_id="HIR1099557.1"
                     /translation="MKWIAAVIGGSLFLGICCISCVEYTPKPRGYVRIEPSKAQYKPL
                     DLSYLPFNFDVSQTAVIEVPDQKKGVTGLNISYPELEAKLYCSYLPITPASLVTVETE
                     SRSFVARLIKSENRISEKAYSNPAANVYGSLFLLDGESASPIQFLLTDSVSNFFRGAL
                     YFDCKPNADSLAPAIQYIREDIIELIQTFSWKE"
     gene            complement(4505..5857)
                     /gene="gldE"
                     /locus_tag="ACZPB4_14985"
     CDS             complement(4505..5857)
                     /gene="gldE"
                     /locus_tag="ACZPB4_14985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gliding motility-associated protein GldE"
                     /protein_id="HIR1099558.1"
                     /translation="MDSDYYLWGLFENVTVQALTAGPVIALSLAFLLLFVSGFVSASE
                     VAFFSLTPGDLNEIGEENRPADPVIKRLLERSEYLLASILIANNFVNVAVVMLCTYAI
                     NAWINFSAAPLLGFVLETILLTFLLLLFGEIMPKIYAQKNSLRFVRFSASVLSGLERF
                     CRPFSKILVNSTSVINKALAKKKYDISVDELSKALELTSTEIPEEKEMLAEIIKFYNK
                     TADEIMTPRLDMEDIEIKISFREVVDFIIKSGYSRIPVYSETEDNIKGILYIKDLLPY
                     IDKPDTFRWQSLIRPAYFVPETKKIDDLLEEFRTNKIHMAIVVDEFGGTSGIVTMEDI
                     LEEIVGEISDEYDEDEQQFIRLADGSLIFEAKILLTDFFRVIDADPSDFGKLTEEVET
                     LAGLLLEIKGDFPRRREIIDFKEYRFQVLEVDNRRILKVKFNRILEDTGNDENGKDTK
                     "
     gene            complement(5883..6392)
                     /gene="ssb"
                     /locus_tag="ACZPB4_14990"
     CDS             complement(5883..6392)
                     /gene="ssb"
                     /locus_tag="ACZPB4_14990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HIR1099559.1"
                     /translation="MSLNKVILIGNVGKDPDVRYFDSGAAVANFPLATSERGYTLANG
                     TVVPERTEWHNIVVRRDLVPFVEKWVRKGSGVYVEGKIRTRNYDDQSGVKRYVTEIHA
                     DRIEFYSTGSRPADGGNTTAQGGSMQPNVGQGQPAQPTTAPNTAYQQPAASQPSAFSE
                     SSDADDLPF"
     gene            6604..8385
                     /locus_tag="ACZPB4_14995"
     CDS             6604..8385
                     /locus_tag="ACZPB4_14995"
                     /inference="COORDINATES: protein motif:HMM:NF012798.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HIR1099560.1"
                     /translation="MEQQIFINEIQTSFVLRQPKSTKPTNIYLVCRIQGKQVKLATGV
                     KVYPEHWNTKKQEAYISVRLTELDNQNNEIANKKIKALRDSVSSYKEYLCDNPDKITN
                     SLNILREYIYKDYKHINRISKMKQQISATLEMKQLIDRQSTKESTKKGNIGAIGYLET
                     FLKASKIDNTWNNINLETLEQFKQYYINKKTNATTINAYIKRILAVCRIANKSSKIQF
                     SFEGNNLHLLELIKDNTNKTKRKNKQVALTEEQVMSLYSYTPKGRKATELEEIRDIFI
                     LQCLVGQRISDMPKFFNGDYKYDSKTNTITITQQKTNEMAIIPLLPLAREILNKYNNK
                     KMIVDINTIKDFRMNKDIKRIAEAVGLNEPIEYQEQKGTDILNITKPLHQMIHSHTAR
                     HTFVTIMCRMGIPKDVVIIATGHEDTTMIDAVYEHLNEQDKANKVHSAFNKLDGKLFK
                     MDQVDTPIIAKDENKPPKPKTNILDYLFAEATLLRLDQLHSRDVNIYELPDISKAIRV
                     IKDLSTISKAQSFLNGIDKTILYGRINKISEILWYIGKHYTDATLYQLYEQKVIELGL
                     SDSINQITSENILHHLWQQEISNEELD"
     gene            complement(8526..9254)
                     /locus_tag="ACZPB4_15000"
     CDS             complement(8526..9254)
                     /locus_tag="ACZPB4_15000"
                     /inference="COORDINATES: protein motif:HMM:NF025695.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Abi-alpha family protein"
                     /protein_id="HIR1099561.1"
                     /translation="MDNLDIPKANLGDYCYGVTKALISSVPYIGSFVAEMLTMYIPSP
                     LESRRDKWMNLMMDMLKELIDKDDSLIERLKNNEEFHTLVIEITQKALCTHLEDKIEL
                     YKCLLRNAILIDTSYYLKSMFIRYVDELHPVQILFIKYINCNKIKLINIDSFSKYYIL
                     FSQDNKISNLTIDHMWFFLKDLERRGLIYVSDNLVHPEFKVAKTHERYNVRSKEPILD
                     QPYISINELGIQFLEMIKKDITED"
     gene            complement(9311..>9759)
                     /locus_tag="ACZPB4_15005"
     CDS             complement(9311..>9759)
                     /locus_tag="ACZPB4_15005"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099562.1"
                     /translation="LLESFLIQVGATNLYPTEDKYAPVDYYFTYKDKKVVAEIKVRDI
                     KYEGYDTHLMEVSKYKSLVKDKKDSQSDTAYYINFFTDGTKVNAYWYSVSSIRNFGTI
                     DYKYCPTTTAVDNGNYYKKVIMIPSNKAQRFALVNGRWNNVLDSKP"
BASE COUNT         3172 a         2101 c         1900 g         2586 t
ORIGIN      
        1 ctgatcatcc acggcatgaa tggcaagccg attaccgcac gtaccgagaa tcaacagtta
       61 ttggtaaagg ctttcgagaa caacgatctg gttttcgcca caggacccgc cggttcgggt
      121 aaaacattcg tcgctatcgc cttagccgta aaagcattaa agaataagga agtacggaag
      181 atcatcttaa gccgtcccgc cgtggaagcc ggagaaaaac tgggtttctt gccgggtgag
      241 atgaaagata agctagatcc ctatctgcaa ccgctttacg atgccttgca ggatatgata
      301 ccggcagcca agctgaagga atatatggag aataacgtga tacagatcgc cccgctagcg
      361 tttatgcgcg gtcgtacctt gaacgacgcc gtcattatat tggacgaggc gcaaaacacg
      421 acgacgcatc aaatcaagat gttcttgacc cgcttgggta tgaacgccaa gatgatcgtc
      481 accggagatg tcacgcagat agaccttccg ccttctacca cgtccggatt gatacaggcc
      541 atgcaaatat tgaagggcgt aaacgggatc ggtaagatcg agttcaccaa gaaagatatt
      601 gtccggcata aacttgtcca acgaatcgta gaggcttatg ataagttcga tgataaacgg
      661 aagaaagaga tcaaagaggc aaaagagaag aaaacgaata tagacaacaa ctaaaagtaa
      721 gagtcatgaa gaaggcatta gttaaaacag acttcaattt cccgcgacaa aagagcgtat
      781 accatgggaa agtacgcgac gtgtacaaca tcaatgacga ggtattggta atggtcgcta
      841 cagaccgtat ttccgctttc gatgttatct tgccggaagg tattccttac aagggacaaa
      901 tgttaaacca gatcgccgcc aagttccttg acgctacgac tgatatttgt ccgaactgga
      961 aaatggctac tccggacccg atggtaacgg ttggcgttca atgccaaggt ttcccggttg
     1021 agatgatcgt acgcggttat ctgtgcggaa gcgcatggcg tgcttataag agcggtgtac
     1081 gtgagatctg cggcgtgaaa ctaccggagg gtatgcgtga gaaccaacgt ttccccgaac
     1141 ccatcatcac cccgaccaca aaggctgaga tcggagagca tgatcaagat atctctaaag
     1201 aggagattct cgctaaaggt ttggtctcta aagaggacta cgaggttctt gagaaatata
     1261 cgatggcctt gtttaaacgc ggtaccgaga tcgctaagga acgtggcttg atcttggttg
     1321 acacgaaata tgagttcggt catcgtgacg gcaagatcta tttgatcgac gagatccata
     1381 ctccggattc ctcccgttat ttctactcag aaggatacga ggatcgtttc gccaaagggg
     1441 aaccgcagaa gcaactttcc aaggagttcg tccgcgaatg gttgatggaa aatggcttcc
     1501 aaggtaaatc cggacagaaa gttcctgaaa tgacaccgga gatcgtagaa ggaatcagca
     1561 accgatatat cgaattgttc gagcatatca caggggagac tttcgtaaaa ggcgagactg
     1621 ataacttgct gaaccgcatc gagaaaaacg ttactgaata tttacagaat aaataagata
     1681 ccgcacatga cacagtatgg ttcagagaca atacttcctt ataacaaaga ggaacaaaag
     1741 ggcacgcaag tcaaacgtat gttcgactcg atagccgaaa cgtatgatca actcaaccat
     1801 actctctcat ttggtatcga caagatatgg cgcaggaaag ggatcgcttt cctgcgtcct
     1861 ttctctccta aaacgatact ggatatcgct accggtaccg gagacttggc tatctccatg
     1921 tacaaaaagc tgcgacccga ccatatcgtc ggtgccgaca tctcgttagg catgatggaa
     1981 gtgggacgga aaaaagtagc tgccgccggt tattcggagc atatatcctt cgagcaacag
     2041 gactgtacgg ccttgaccta cgaggaaaac tcgttcgatg ccgtaaccgc cgctttcggg
     2101 gttcgtaatt ttgagaacat agagcaaggt atctcagaga tgtaccgggt gctgaaaccc
     2161 ggtggacata tcatgatctt ggaactttcc acaccggaac attttcccat gagacaactc
     2221 taccagatct attcaaagac cgtcatcccc tttatcggac gtctactctc taaagaaaaa
     2281 gtcgcgtata attatttgcc ggcttccatc aaggtagttc ctcagggaaa gatcatgacg
     2341 gatttactca cccgccaagg cttcaagcag gcccgtgtac ggacctttac cttcgggatc
     2401 tgttcattat atacaggatc taaagaataa acaataaaaa ggttatgcag aaatatggct
     2461 tactgggata tcccctcgga cattcgtttt ctaaaacgta tttcaaccag aagtttgagg
     2521 cggagaagat cgacgctgag tacttgaatt tcgagattcc ctctatcaag gagattaaga
     2581 acgtaatcaa agaaaaccct gaacttaacg gtttaaacgt gaccattcct tataaggaac
     2641 aagtaatccc atatttagac gatttggatg acgatgcccg tcagatcgga gcggtaaatg
     2701 tcatcaagtt cacaaaaggt cttttcggca aacttaaact gaaaggatat aactcggata
     2761 ttatcggatt caagcaatcg attgatcctt tattgaaaga aacgcaccgg aaagcgttga
     2821 tccttggtac gggaggggcg tcaaaggcag tcttccatgg actgaaacag ctaggtgttg
     2881 gtgccacgct ggtttctcgc aaaccgaaag aattttgtat cacgtacgat gagattactc
     2941 cgaagaccat ggagcaatat acggtgatcg tgaatacgac tcccttaggc atgttcccga
     3001 atatagactc atgtccggat atcccgtacg atttacttac gccgaatcat ctattgtatg
     3061 atttacttta caatccggat gagacccttt tcatgaagaa aggaaaagaa aaaggcgccg
     3121 tcgtgaaaaa tggtctggaa atgcttctat tacaggcttt cgccgcttgg gagatctggc
     3181 agaaatagat cgaacgatat ctttccaacc acatgatttg atgaagctag cttcgtgagc
     3241 caatgaagtt agcttcgtta gtcaatgaag ttaacttcac aagcgtatga agttaactta
     3301 cttcaaccaa gtcaatacat agtccggtgt aacttgatat gccaactcat attcccggca
     3361 tgcctcggtc cgggtttctc gtcccttaaa cgtcccactc gataaataag gaaaaggatt
     3421 cacgtgaaga tgcttttgaa agtccactcc ttcctgcccg attatcttga acaaggtttc
     3481 tttggcgcac caatggatta atagatgctc gacctcatgc tccagatcga tacccgcctc
     3541 ttcctccgga ttcataaagc gacttcgtat tttcaagatc cggtccgaac gatactcgat
     3601 atcgatccct gtcggacgct tatccaagat taccgccaca taatctttcg tatgagatat
     3661 acttatatat aaaggtacgc acgcaaggaa cggggcaccc gtagaatgat agtcaaccct
     3721 tgcctcctct cctaaaagct cttttaaaag cacccggctg gcgaaacgtt cctgcctccg
     3781 cttctctgcc gatacccgct ccaaaaaaga agaatagtcc gctttatgct caagcatccc
     3841 caaaagctca tcagagcttt cttccatttt ccagactcca tgcagcggcg agagttgttt
     3901 atatagcaag gccatattat tctttccaac taaaagtttg tataagttct atgatatctt
     3961 cccggatata ttggatagcg ggagctaatg aatccgcatt gggtttacag tcaaaataca
     4021 aggccccccg gaagaaattc gatacactat ctgtcaacag gaattgtatg ggagaagccg
     4081 attctccatc cagaagaaac aacgagccat aaacgtttgc ggcagggttg gaatacgctt
     4141 tctccgatat ccgattctcc gactttatca ggcgggcgac gaaagagcgg ctttccgttt
     4201 ccaccgtcac caaggacgcg ggagtaattg gcaaatagct gcaataaagc ttagcctcta
     4261 actccggata cgagatattc aagcccgtaa cacccttctt ttgatccgga acctctatga
     4321 ccgcagtctg agagacatca aaattaaaag gcaggtaact gagatcaagc ggtttatact
     4381 gtgccttcga aggttcaata cgaacatagc cccgtggctt cggcgtatat tccacacacg
     4441 aaatacagca tatccctaaa aacagagaac ctcctatgac agcagctatc catttcataa
     4501 acatttactt cgtatctttc ccattctcat cattccctgt atcttcaagg atacggttaa
     4561 atttaacctt taatatcctc ctgttatcca cttccagcac ttggaaacga tattccttaa
     4621 aatctataat ctccctacgg cgtggaaaat ccccttttat ctccaacaaa agaccggcca
     4681 aagtttccac ttcttccgtc aatttaccaa aatctgaggg atcggcatcg ataacccgga
     4741 agaaatccgt caataatatc tttgcctcaa agatcaagct accgtctgct aaacggatga
     4801 attgttgctc atcctcatca tactcatcgg agatctctcc aacaatttcc tctaggatat
     4861 cttccatcgt cacgataccg gaggtaccgc caaactcatc gaccacgatc gccatatgaa
     4921 ttttattggt acggaactct tccagcaaat catcgatctt cttggtttcc ggcacgaaat
     4981 aggccggtcg gatcaagctc tgccaacgga atgtatcggg cttgtcaata tagggcaata
     5041 agtccttgat atataagata ccttttatat tatcctcagt ctcggaatat accggaatac
     5101 gcgaatagcc ggatttgata ataaaatcaa ccacctcacg gaaactgatc ttgatctcga
     5161 tatcttccat atccagacga ggagtcatga tctcatcagc ggtcttatta taaaacttga
     5221 taatctccgc cagcatctcc ttctcctccg ggatctcggt agaggttagc tctaacgctt
     5281 tagaaagctc atctacagag atatcatatt tctttttcgc taacgcttta ttgatgaccg
     5341 atgtggaatt aaccaagatt ttcgagaatg ggcggcagaa gcgttccaaa ccacttaata
     5401 cggaggctga aaaacgaaca aaacgcaaag aattcttctg tgcgtaaatc ttaggcatga
     5461 tctccccaaa aagtaaaagc aagaaagtca agagaatcgt ctcaagcaca aagcctagaa
     5521 gaggagcggc cgagaaatta atccaagcgt taatcgcata ggtacacagc ataacgaccg
     5581 ccacatttac aaaattatta gcgatcaata tagatgccaa tagatactcc gaccgttcaa
     5641 ggagacgttt gataacagga tctgccgggc gattctcttc cccgatctca tttaggtcac
     5701 ccggggttag agaaaagaat gccacttcag aggccgacac gaagccggaa acaaacagca
     5761 gtaaaaaagc gaggcttaat gcgatcacag gacccgctgt cagcgcctgc accgttacgt
     5821 tttcaaataa gccccataaa taatagtccg agtccaaggg aaacagtatt agttaaacaa
     5881 tatcagaacg ggagatcatc cgcgtcactg gattctgaga atgcgctagg ctgcgaggcg
     5941 gctggctgtt gataagcggt atttggcgcc gtggtcggtt gagccggttg tccttgtccc
     6001 acattgggct gcatactacc gccttgtgca gtcgtatttc caccatcggc cggacgggaa
     6061 cccgtgctgt aaaactcgat acgatccgca tggatctccg taacatatcg tttcacgccg
     6121 ctttggtcat cataattacg agtacgaatc ttgccttcca catatacacc ggaaccttta
     6181 cgtacccatt tttccacgaa aggaaccaaa tcccgacgaa ctacgatatt atgccactcc
     6241 gtacgttccg gaaccaccgt tccatttgcc aacgtatacc cacgttccga ggttgccagc
     6301 gggaaattag cgacagcggc accactgtca aaatagcgaa cgtcaggatc tttgcctacg
     6361 ttgccgatca atataacctt attcaatgac ataattcaaa ttcttaataa ccatacaaag
     6421 aaacacaaat tcaatcattc tcacaagttt ccgtttaatt tctctaaatc agatagtgaa
     6481 atttcaccta tgtgagtttc aagactatag aagagacagt tgtagagatc tcattcacag
     6541 atggtatcta aaagaaccaa attgaagaac gaatttgaag aaccaaatta aagaaccgat
     6601 atgatggaac aacagatatt cattaacgag atacagacat cttttgtatt gaggcaacca
     6661 aagtcaacta agccgaccaa tatctattta gtatgtcgga tacaagggaa gcaagttaaa
     6721 ctagctacag gggttaaagt gtatccagag cactggaaca caaagaaaca agaagcctat
     6781 ataagtgttc gtctaacaga actagataat cagaataatg aaatcgccaa taaaaaaatt
     6841 aaagcactta gagacagtgt atcgtcttat aaagagtatc tttgtgataa tcccgacaag
     6901 atcacgaaca gcttaaacat cctgcgggag tatatctata aagactataa gcatataaat
     6961 agaattagta aaatgaaaca gcagatcagc gcaacattag aaatgaagca acttatagat
     7021 aggcaaagca caaaagaatc taccaagaag gggaatattg gtgctatagg atacctagaa
     7081 acattcttaa aagcatccaa aattgataac acttggaata acataaacct tgaaacacta
     7141 gagcagttca aacaatatta tataaataag aagactaacg ctactacgat caatgcttat
     7201 atcaagagga tacttgcagt atgcagaatt gctaacaaat ctagcaaaat tcaatttagc
     7261 tttgagggta acaacttaca cttattagaa ttaattaagg ataacactaa taaaactaag
     7321 cgtaagaata aacaagtggc actaacggag gaacaagtaa tgtcactata cagctacacc
     7381 ccaaaaggaa ggaaagctac agagttagaa gagattagag acatatttat acttcaatgt
     7441 ttagttgggc aacgtatatc agatatgcct aaattcttta atggagacta caagtatgat
     7501 agcaagacta acaccataac tataacacaa caaaaaacta atgaaatggc tatcatacca
     7561 ttacttccat tggctagaga gatattaaac aagtacaata ataaaaagat gatagtagat
     7621 ataaatacta ttaaagactt tagaatgaat aaagatatta aacgtattgc cgaggctgta
     7681 ggacttaatg aacctataga ataccaagag cagaaaggta ctgatatatt gaatattacc
     7741 aaaccattac accagatgat acattcacac accgcaaggc atacatttgt cacaattatg
     7801 tgtcgtatgg gaatacctaa agacgttgtg attatagcaa ctggacacga agatacaact
     7861 atgatagatg cggtatatga acatcttaat gaacaggaca aagccaacaa ggtacattcc
     7921 gcattcaata aattagatgg taaactattt aaaatggatc aagtagacac tccaattata
     7981 gctaaagatg agaataagcc tccgaaaccc aagactaata tattagatta tttatttgcg
     8041 gaagctactt tattgagact tgaccaacta catagcaggg atgtcaatat ttatgagttg
     8101 ccagatatat ctaaagcaat cagagttatt aaagacctat ctactataag taaagctcaa
     8161 tcattcttaa atggcattga caaaactata ctatatggac gtattaataa gatctcagaa
     8221 atattatggt atataggtaa acattataca gatgctacat tatatcagtt atacgaacaa
     8281 aaggttattg agctaggttt atcagatagc attaatcaga tcacgagtga gaatatatta
     8341 caccatcttt ggcagcagga gataagtaat gaagagctag actgaaactc caacacaaaa
     8401 ttaagcttaa tcctttaaca ataaacccca gcccaccaat taaggcaagc tggggtaata
     8461 agttgtaatt taaggagaca ctgtccagtt tattttatgc gtcccactct ttctgaatat
     8521 tctagctagt cttcagttat atcttttttt atcatttcta aaaactgtat acccaattca
     8581 tttatggaaa tgtagggctg atctaatata ggttctttac ttctgacatt atatctttcg
     8641 tgagtctttg caactttaaa ttctggatga accaaattat cactaacata gattaacccc
     8701 cgtctctcta agtctttaag gaaaaaccac atatggtcaa ttgttaaatt gctaatttta
     8761 ttatcttgac taaacaatat ataatatttc gagaatgaat ctatattaat caatttaatc
     8821 ttattgcagt ttatatactt aataaataga atttgtacag gatgtaactc atccacatat
     8881 ctaataaaca tagattttaa ataatatgaa gtatctatca atatagcatt cctcaataga
     8941 catttatata actcaatctt atcttctaaa tgtgtacaca acgctttctg agttatttct
     9001 ataacgagag tatgaaattc ctcattattc tttaatcttt caattaaact atcatcctta
     9061 tctattaatt ctttcagcat atccatcatt aaattcatcc atttatctct acgagactct
     9121 aaaggcgaag gaatatacat cgtaagcatt tcagccacaa agctacctat ataagggacg
     9181 ctagaaataa gtgcctttgt tacaccatag caataatcac ctaaatttgc tttaggtata
     9241 tctaaattat ccatattgac attattaata gtactacaaa tataacaaca aagtttaata
     9301 caagcaacct ttaaggttta gaatcaagga cattgttcca cctaccattt accaaagcaa
     9361 atctttgagc cttatttgaa gggatcataa taaccttctt atagtagtta ccgttatcga
     9421 ctgctgtagt agtcgggcag tacttataat ctatagtacc aaagttccta atactgctta
     9481 cagagtacca ataagcatta actttagttc catctgtaaa gaagttaatg tagtatgctg
     9541 tatctgactg gctatctttc ttatccttca ctaaggactt atatttagac acttccatta
     9601 agtgagtatc atagccttca tacttaatat ctcttacctt tatttcagct accaccttct
     9661 tatccttata agtaaaatag tagtccactg gtgcatattt atcttctgta gggtacagat
     9721 tagtagcacc cacttgtatt aaaaatgatt ctaatagtt
//
LOCUS       DBMDTB010000126         9636 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_2001_length_9636_cov_9.839434, whole genome shotgun sequence.
ACCESSION   DBMDTB010000126 DBMDTB010000000
VERSION     DBMDTB010000126.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 9636)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 9636)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9636
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2001_length_9636_cov_9.839434"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..345
                     /locus_tag="ACZPB4_15010"
     CDS             <1..345
                     /locus_tag="ACZPB4_15010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008771634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008081 - phosphoric diester hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase family
                     protein"
                     /protein_id="HIR1099563.1"
                     /translation="KRMKLAKRTDYISFNMDACKEFIRLCPKSEVSYLNGELSPMELK
                     ELGFTGLDYHYKVLQSHPDWVKDCKVLGMTSNVWTVDDPKLMEEMIDLGVDFITTDLP
                     EETQKILHSRAQ"
     gene            358..1845
                     /locus_tag="ACZPB4_15015"
     CDS             358..1845
                     /locus_tag="ACZPB4_15015"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 10 protein"
                     /protein_id="HIR1099564.1"
                     /translation="MRKFCLLLILSLALPVFCLLQAVEPPKKEIRAVWLTTVYGLDWP
                     HKPATTEAGRKAQQQALLDILDRLQEANFNMVFIQARLRGDVMYRSAIEPVSKTFSGK
                     YGELPGYDPLAFVVDECHKRGMECHAWFVTFPLGTEKSVKEQGKLSVVKKKPKLCKRH
                     NGEWYLDPGVPETADYILSLVKEIVNGYDIDGIHFDYIRYPEEAKKFPDKALYNKSGK
                     KKSLADWRRENINRMVYRIYDWVKQTKPWVQVSSSPLGKYNRIERVPNAGWTAYESVF
                     QDPKMWMQQGKQDMIVPMMYYLHKNFFPFVDNWVDNCNGRLVVPGLGAYRMDKSEADW
                     AVNDITDQIDYSRYYGGAGCAFFRCGNVLYNDKGLYKELRDNYYKYPAQLPPLTWLND
                     SVPAAPEGIKVERLDDELHLTWQKPVSEKQDLTYTVYYSLTDSIDTASAKSILATNIY
                     GNELFLPIDVESERGYTFSVTASTRYRIESEPSPDTYYYLSKFIK"
     gene            1891..2319
                     /locus_tag="ACZPB4_15020"
     CDS             1891..2319
                     /locus_tag="ACZPB4_15020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011965994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099565.1"
                     /translation="MRRFATSLFLVILASLIFYGGAGVNFVSYCCGVCEKEGVEALLE
                     AKCCEIHGHDHSRDKLANNTVECCGMNGCGIERVDFDWNSVNIQVPDLQPVVHDLLFS
                     SIFESLQIASLFADSYEIRVIGPPVSCPRVYLSLLTTLLI"
     gene            2433..4670
                     /locus_tag="ACZPB4_15025"
     CDS             2433..4670
                     /locus_tag="ACZPB4_15025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor plug domain-containing
                     protein"
                     /protein_id="HIR1099566.1"
                     /translation="MLRQLYLIFLLSCLTFTLTWAEDSGKKVKGRVCDENKQPIIGAN
                     VYWEGTQNGTTSDVDGNFELERKGDSKNLVVSYIGYMTEVTPVDEKDDAMQIFLKGEI
                     ALDEVVVSERKMGTIASRTSVLQTQKITYDEICRAACCNLAESFETNPSVDVSYSDAA
                     TGARQIKLLGLAGTYVQMLTENYPNFRGAASLYGLDYVPGAWMESIQVSKGTSSVKNG
                     YEALAGQINVEFKKPPTADIFSANVFASDAGRYEGNADASWHINDKLSTGLLVHYSND
                     KMQHDGNDDGFLDTPLREQVNVMNRWYHKLDKYVAQYGVRYLHESRTGGQDTKHHDFT
                     DPYRIHLNTNRAELFTKQAYIIDKEKVESVALILSGSYHEQKSRYDRTPYNVYQNNVY
                     ASLLYEKEFTPMHSLSTGLSMNYDGFDENLVQYAGGESVRHAYDRTEVVPGAYAQYTF
                     NLNDKLILLVGVRADYSTLYDFFVTPRVHIKYNPFDWFHIRASAGKGFRTANVLAENN
                     FLLSSSRKMYIADNLDQEEAWNTGLNLSFYIPLFGKELSLSGEWYYTDFLKQIVVDMD
                     SDPHAVRFYNLDGRSYSNSFQVEASYPFFRGFTLTAAYRYTDAKTDYRNEEGVAHRLK
                     KPLVSDYKGLLTASYQTPLKKWQFDLTSQFNGGGRMPTPDASNPLWEPNFKAYTVVNA
                     QITKYFRQWSIYVGAENLFNYKQPNPIIDASNPRGDNFDGSMVWGPVHGRKIYAGIRF
                     NISRD"
     gene            4833..5183
                     /locus_tag="ACZPB4_15030"
     CDS             4833..5183
                     /locus_tag="ACZPB4_15030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HIR1099567.1"
                     /translation="MKRLIMLLFCAVCTVSMTFAQDAKKKKDSVTFFIEAMDCDHCIK
                     KIEKNIAFEKGVTDLKCDLSTRTAIVTYKTDKTSKTRLAAAFKKIGMEAVPVDNGAGC
                     PVPPVKKSEHTHAH"
     gene            5352..5879
                     /locus_tag="ACZPB4_15035"
     CDS             5352..5879
                     /locus_tag="ACZPB4_15035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HIR1099568.1"
                     /translation="MNELQLIEGCRKGERRAQKELYDAYSRKMMGVCLRYVNDRETAR
                     DLLQDGFVKIFTSMDSYTGSGSFEGWMRKIFVNCALEYLRKSDVLREATDLDNTAELI
                     QPDSSAISDMSAAELMNLVKELPVGFRTVFNMFAIEGYSHKEISEMLNITESTSRSQY
                     TRAKQLLQRRINALY"
     gene            5886..7154
                     /locus_tag="ACZPB4_15040"
     CDS             5886..7154
                     /locus_tag="ACZPB4_15040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0015288 - porin activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="porin family protein"
                     /protein_id="HIR1099569.1"
                     /translation="MSKKERDIWDDAIRSKLEDFEMDTLPGDWEAIADRLPGKAPVPL
                     RRTLRYWVAAAVISLLVVSGGIYLYDREMEDLPIAQEIQSSQESTSVDTPVVPIEKTM
                     EQAPVLATIPAAAVVKAKAASGAVKVEDKARMAVFRQNVESAGDRPISESEVMSADRS
                     ANEKDTVEPEVERNNDEIVVLKNDVLVADATPVTKKKPEKTASRKWGFGMGGGGLSMG
                     ADNLVPQYVTNSSVLKSENLMSLNSFDAEKKDPAKTDIHHKTPIGVGISISRYLNNRF
                     SLQTGLTYSYLRSEWSTNNTYHIENDQRLHFIGIPLSLTYKIAEWNRFMFYASAGGMA
                     EVNVAGKRRMKLFSDEVEIAKQSEHIRMKEWLWSVNARAGVSYPIIRFVSAFAEVGAS
                     YYFDNGSEIETIHSEKPFNMSLQFGFRFGF"
     gene            7210..7983
                     /locus_tag="ACZPB4_15045"
     CDS             7210..7983
                     /locus_tag="ACZPB4_15045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BFO_2992 family lipoprotein"
                     /protein_id="HIR1099570.1"
                     /translation="MKAFKLIGAAVAASLLLLTSCLGESNNTVTRAGFGVAGLSEKTY
                     KTVLNTNMGALYSPSLSAQVVDGACYLINYELDLNSPENANAATNGYLTATISVADEI
                     TKGQPVFYNVPDSASLLQNEIPVKNLFSNGDYGVYVDGYLFFFITMDMFKDQKNSYTL
                     YWDRSKEPTMVDNVPTYDLFLRVAKVADGTGSAASSIGEVRAFNVKSVLESVNSAEAN
                     KDSKSFNLKVNYLNTINEKDSTDLKWASYTVLFQVVKNS"
     gene            8112..8873
                     /locus_tag="ACZPB4_15050"
     CDS             8112..8873
                     /locus_tag="ACZPB4_15050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BFO_2992 family lipoprotein"
                     /protein_id="HIR1099571.1"
                     /translation="MRYKNLIGFVWVAVFMSLFTSCLKDINNVYNPGTTAAVVRQHGD
                     SALMMANTRFGWIYSTKLSSYSEGKCLLVSFDYDPSLPENTNAEQKGYYTVTIQGETA
                     VNQQNAESPLTDTHKLLTNEQPVLAVNPNDSVLYIELEDYLFLPSACWTTKDRTLNWQ
                     LTYDPAQEAVVENRKSIYSLYLRAAATTGKPEDKAEEAIAVINAFNLGNFIKDMREQG
                     GRDADMYVRIHYIDQINPKDSTQFTWGVTDPLLIK"
     gene            8879..9628
                     /locus_tag="ACZPB4_15055"
     CDS             8879..9628
                     /locus_tag="ACZPB4_15055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011965996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BFO_2992 family lipoprotein"
                     /protein_id="HIR1099572.1"
                     /translation="MRKRILYGLFLSLFFLMTSCMGDGSNSINYHRVGVIRENPMRCI
                     YTADDQGEIFIVSSSEFENRTDLKDGDCCVVDFKTNFSEELGNGVYNAEIYKYDSVAV
                     WPLHETLTDTTVVLDKERLVTLDFKKSIYLEGRFFLQTQHVNHQVDQKDIFNLSYNPD
                     QEVEEDSTGQRVYNLYLRVTQEGGTGDSTKWVNTTAFTIDKFLDQAKAIESSEGQNVI
                     NFKINYAERYNADTTACVWGATDVFTLRFTN"
BASE COUNT         2695 a         1708 c         2455 g         2778 t
ORIGIN      
        1 aagcgtatga aattagcgaa acgtacggat tacatatctt ttaatatgga tgcttgtaaa
       61 gaatttatcc gtctatgtcc gaaatctgag gtttcttatc tgaatggaga attatccccg
      121 atggaattga aagagcttgg ttttacagga ttagactacc attataaagt cttgcaatct
      181 catccggatt gggtgaagga ttgtaaagtc ctaggcatga cttcgaatgt ctggaccgta
      241 gatgacccta aattaatgga agagatgatc gatctgggag tcgattttat tacgactgat
      301 ttaccggaag agactcaaaa aatactacat tcgcgggctc aataaggcat tataaagatg
      361 agaaagtttt gtctgttgct tatcctgtcg ctggctttac ccgttttttg tctgttacaa
      421 gcggtggagc ctcccaaaaa ggaaattcgt gcggtttggt tgactacggt ttatggtctg
      481 gattggcctc ataaaccggc tactaccgag gcgggacgaa aagcccagca acaggcattg
      541 cttgatatct tggaccggct tcaagaagcg aattttaata tggtcttcat tcaggctcgc
      601 ttgaggggag acgtgatgta tcgttcggct atcgaaccag tcagtaagac attctccggt
      661 aagtatggag aattaccggg atatgatccg ctcgcttttg tcgttgatga atgccataaa
      721 cggggaatgg aatgtcatgc gtggttcgtg actttcccgt tgggaacgga aaaaagcgtg
      781 aaggagcaag gaaagctttc cgtggttaaa aagaaaccaa aactctgcaa acggcataat
      841 ggagagtggt atttggaccc cggtgtaccg gagaccgctg attatatctt atccttagtc
      901 aaggagatcg tgaatggcta cgatatagat ggcatccatt ttgattatat ccgctatccg
      961 gaagaggcga aaaaattccc ggataaagcg ctgtataata aatccggtaa gaaaaagtct
     1021 ctggcagact ggcgtaggga gaatatcaac cggatggttt atcgtattta cgattgggta
     1081 aagcaaacga aaccttgggt acaggttagc agttcgccac tcgggaaata taatcgtatt
     1141 gaacgggtac ctaacgcggg ttggaccgct tacgaaagtg tcttccaaga ccctaagatg
     1201 tggatgcaac aaggtaaaca agatatgatt gttccgatga tgtattacct gcataagaat
     1261 ttctttcctt tcgtggataa ttgggtggat aattgtaacg ggcgtttggt cgtacccggc
     1321 ttgggagctt atcgaatgga caagagcgag gcggactggg ccgtgaatga tataactgac
     1381 cagatcgatt atagtcgtta ttacggagga gccggctgtg cgttctttcg ttgtggaaat
     1441 gtcctgtata atgataaagg actctataaa gagttgagag acaattacta taaatatccg
     1501 gcccaattgc ctccgttgac ttggctgaat gattcggtac ctgccgctcc agagggcatc
     1561 aaagtggaac gtttggatga tgagttgcat ttaacttggc agaaacctgt gtcggaaaag
     1621 caggatttaa cttataccgt ttattattca ttgacggatt cgatcgacac agcttcggca
     1681 aaatccatat tagctacgaa tatttatggc aacgagcttt ttcttcctat cgatgtagag
     1741 tctgaacgtg ggtatacatt ttctgtaacg gcttccaccc gttaccggat agagagtgaa
     1801 ccttctccgg atacctatta ttacctgtct aaatttatca agtaaaggga gtattttgat
     1861 ttcgagtttt tttgcttatt tttgcggcat atgagacgat ttgccacatc cttgtttctt
     1921 gtaattcttg cttccttaat cttttatggg ggagcggggg ttaatttcgt atcttattgt
     1981 tgtggcgttt gcgagaaaga gggagtggag gctttattgg aagctaagtg ctgtgagatt
     2041 catggacatg atcatagtcg tgataagctt gcgaataata cggtggagtg ttgtggcatg
     2101 aacggctgtg gcattgaacg ggttgatttt gattggaatt ctgtaaatat acaagtaccg
     2161 gatctgcaac cagtcgtaca tgatttgctc ttttcctcta ttttcgagag tttacaaatt
     2221 gcttccttat ttgctgattc ctatgagatt agggtgatag gtcctcccgt atcctgtcct
     2281 cgtgtgtacc tttctttatt gactacgctt ttgatttgat tgtattcgtg agggtggaag
     2341 ctgctcgcta aatacccttt ggtttttaag gtaggggatg ctctatccct gcggaagcat
     2401 gtatttaacg attcaatcaa ataacaacta tcatgttaag acaattatat ctgatatttt
     2461 tactgtcctg tttgactttt actttgactt gggccgagga ttccggcaag aaagtgaaag
     2521 gacgtgtatg tgatgaaaac aaacaaccta ttatcggtgc aaatgtatat tgggaaggaa
     2581 cccaaaatgg aaccacgtcc gatgtggatg gaaatttcga gttagaacga aaaggtgact
     2641 ccaagaatct ggtggttagc tatatcggtt atatgactga ggtcacccct gtggatgaga
     2701 aggacgatgc tatgcagatt ttcttaaaag gtgagatcgc cttggatgag gtcgtggtta
     2761 gtgagcgcaa gatgggaacc atcgcttccc gtacgagcgt attgcaaact cagaaaatta
     2821 cgtacgatga gatttgccgt gcggcctgct gtaatctggc ggagagcttt gagacaaatc
     2881 cgtctgtcga tgtatcgtac tcggatgcgg ctacaggtgc ccggcaaatt aagctgttgg
     2941 gattggcggg aacctacgta caaatgttga ccgagaatta cccgaatttc cggggggccg
     3001 cttccttata tggcttggat tatgttccgg gagcttggat ggaaagtatt caggtgtcta
     3061 aaggaacctc ttcggttaag aatgggtatg aggcgttggc cggacaaatc aacgtggaat
     3121 tcaagaagcc ccctacggcg gatattttct ctgctaatgt gttcgctagt gatgccggac
     3181 gttatgaagg gaatgcggat gcttcttggc atatcaacga caagctctct accggtttat
     3241 tggtacacta ctcgaatgat aaaatgcaac atgacggtaa tgacgatggt tttctcgata
     3301 cgccgctaag ggaacaggtg aacgtaatga atcgttggta tcataaattg gataaatacg
     3361 tggctcaata cggagttcgc tatctgcatg agagccgtac cggtgggcag gatacgaaac
     3421 accatgattt caccgacccg tatcggattc atttaaatac gaaccgggcc gaattattta
     3481 cgaagcaggc ctatattatc gataaggaaa aggtagagag cgtggcattg atactttccg
     3541 gttcttatca tgagcaaaaa tcaagatatg accgtacgcc ctataatgta tatcagaata
     3601 atgtatatgc cagtttgctg tatgaaaagg agtttacgcc gatgcatagc ttgagtaccg
     3661 gattaagtat gaactatgat ggtttcgacg agaatctggt tcaatatgcg ggaggagagt
     3721 cggtccgtca tgcctatgac cgtacggaag tcgtgccggg agcttatgcc caatatacgt
     3781 tcaatctgaa tgataaactg atcttattgg tgggtgtacg tgcggattat agtacgttgt
     3841 atgatttctt tgtaacccct cgtgtacata ttaaatataa tccttttgac tggttccata
     3901 tccgggcttc ggcaggtaaa ggatttcgga cagcgaatgt gctggcagag aacaactttt
     3961 tgttatccag tagtcgaaaa atgtatatcg ccgacaatct ggatcaagaa gaagcgtgga
     4021 ataccggtct gaatctgtca ttttatatac ctttgttcgg gaaggaactg agcttgagcg
     4081 gggaatggta ttataccgat ttcttgaagc aaatcgtggt ggatatggat agtgatcctc
     4141 atgcggttcg tttctacaat ctggatgggc gttcctattc gaatagcttc caagtggagg
     4201 cttcctatcc ttttttccgg ggatttacgt taacggccgc ttatcgttat acagatgcga
     4261 agaccgatta ccggaatgag gagggggtgg cgcatcgatt gaaaaagccg ttggttagtg
     4321 attataaagg tttattgacc gcttcttatc aaaccccgtt gaaaaaatgg cagtttgatt
     4381 tgaccagcca gtttaatgga ggtggccgta tgccgacacc ggatgcatct aatccgttat
     4441 gggagccgaa ttttaaggct tatacggtag tgaatgcgca gattacgaaa tatttccgtc
     4501 aatggtctat ttacgtggga gcggagaacc tgtttaatta caaacaaccg aatccgatta
     4561 tcgatgccag caatcccaga ggggataact tcgatggatc tatggtgtgg ggaccggtgc
     4621 atggacggaa aatttatgcg ggtatccgct ttaatataag cagggattga cacgtatata
     4681 cgtataagcc cgcacgtata tacgtgtagg cctatgcgta tactggtgtg gccctacgcc
     4741 tatatacgtg tagcccgatg cctatagtgg tgcttttctt ttggtagata tgaatggata
     4801 attagaattg ttaatattaa aaatgattga ttatgaaacg attaattatg ttgctgtttt
     4861 gtgctgtatg tacggtatcg atgacattcg cccaagacgc gaaaaagaag aaggactctg
     4921 tgacattctt tatcgaagcg atggattgtg atcactgtat caagaagatc gagaaaaata
     4981 tcgctttcga gaaaggagtg accgacttga aatgtgatct gagcacccgt acggccattg
     5041 tgacttacaa gacggataag acttcgaaga cccgcttggc cgcggcattc aaaaagatcg
     5101 gtatggaagc ggttccggta gataatggcg ccggttgtcc ggtacctccg gtgaaaaaaa
     5161 gtgagcatac tcacgctcat taacatggaa attcataaga acatcttatc tttgcagatg
     5221 ttccgtgagg gcgggccgga gtgtccgccc tgtttatgaa ataatttttc tacggaatgc
     5281 agcgtttgtt taattattta catcctaata ttgtacagtc tccagaaggg agacgttcaa
     5341 ggcacgactg aatgaatgag ctacaactga tagagggttg tcggaagggg gagagacgag
     5401 ctcaaaaaga gctttatgat gcatattccc gaaaaatgat gggagtttgc cttcgttatg
     5461 tgaacgacag ggaaacggct cgtgatttgt tgcaggatgg cttcgtgaaa atctttacca
     5521 gtatggattc ctatacaggg agtggttcat ttgaggggtg gatgcggaag atctttgtta
     5581 attgtgcgtt ggaatatctg cgaaagtcgg atgtgttgcg tgaagcgacc gatcttgaca
     5641 atacggcgga actgattcaa cccgatagtt cggctatctc ggacatgtcg gcggctgaat
     5701 tgatgaatct agtgaaggag ttgccggttg gcttccgtac cgtattcaat atgttcgcga
     5761 tagagggata ttctcataag gagatcagtg agatgttgaa cataacagag agtacttccc
     5821 gttcacaata tacccgtgcc aagcagttat tacaacgtag aattaacgca ttgtattgag
     5881 ataagatgag taaaaaggaa agagatatat gggatgatgc gatccggtcg aagctagagg
     5941 atttcgagat ggatacgcta cccggcgact gggaggctat agccgatcga ttgcccggaa
     6001 aggctccggt tcctttgcgt cgtacgcttc gctactgggt tgccgccgcc gtgatctcct
     6061 tattggtcgt atcgggtggt atctatttat atgacaggga gatggaagat ctacctatag
     6121 cccaagaaat acagtcttca caagagtcga catccgtgga taccccggtt gttccgatag
     6181 agaaaacgat ggagcaagcg cccgtattag caactattcc tgctgctgcg gtcgtgaagg
     6241 caaaagcggc atctggagcg gttaaagtgg aagataaggc taggatggca gtgttccggc
     6301 aaaatgtaga gagtgcaggg gatcggccta tttctgagtc ggaggtaatg tctgctgata
     6361 gatcggcgaa tgagaaagat accgttgaac cggaggttga aaggaataat gatgagatag
     6421 ttgttctcaa gaatgatgta cttgtcgcag atgctactcc tgttactaaa aagaagccgg
     6481 agaagaccgc gtctcggaaa tgggggttcg gtatgggagg tggaggtctt tccatgggcg
     6541 ctgataatct ggtccctcag tatgtgacga atagcagtgt gcttaagagc gagaatctga
     6601 tgagcttaaa ttcgttcgat gcggagaaga aagatcctgc taagacggat attcatcata
     6661 agacgcctat tggggtgggg atctcaatta gtcgttattt gaataatcgt ttttctttgc
     6721 agactggatt aacttattct tacttaagat cggagtggag tacgaataat acgtatcata
     6781 tagagaatga tcagcgattg cattttatag gaattccatt atcattgact tataagatcg
     6841 cggaatggaa tcgttttatg ttttacgcct cagccggagg tatggcggaa gtgaatgtcg
     6901 ctggcaaacg tagaatgaaa ttattctcgg atgaggtaga gatcgcaaag caaagcgaac
     6961 atattcgaat gaaagaatgg ctatggtctg taaatgcccg tgcgggtgta agttatccga
     7021 ttatccgttt tgtaagcgct ttcgctgagg tgggagccag ctattatttt gataatggta
     7081 gcgagatcga aaccatccat tcggagaagc cgtttaacat gagtcttcag ttcggatttc
     7141 gttttggttt ttaatactcg atagattaac agtgtaaata caaatactta aaaatagaaa
     7201 aattgaatta tgaaagcatt taaattaatt ggagcagcgg tggctgcgtc attattgttg
     7261 ttgacctctt gtcttggaga atcgaataat acggtgactc gtgccggctt tggtgtcgca
     7321 ggtctttctg aaaagacata taaaacggta ctgaatacaa atatgggagc attatactct
     7381 ccgtctttat cggcacaagt agttgacgga gcttgttact tgatcaacta tgaattagac
     7441 ctaaattctc cggagaatgc gaatgcggcg acaaatggtt atttaacagc gacaatctct
     7501 gtggcagatg agataacaaa aggacagcca gtcttttata atgtgccaga ttcggccagc
     7561 ttacttcaga atgagatacc tgtaaaaaac ctatttagca atggcgacta tggggtgtat
     7621 gtagacggtt atttattctt ctttataaca atggatatgt ttaaggatca gaaaaattct
     7681 tatactttat attgggatcg ttcaaaggag cctactatgg tggataatgt cccgacatat
     7741 gacttgttct tgcgtgtcgc taaagtagcg gacggaacag gttctgcggc atcatctata
     7801 ggagaagtcc gtgcgtttaa tgttaagtct gtattggagt ctgtgaatag cgctgaggct
     7861 aataaagatt caaagtcttt taatcttaag gtcaattatc taaatacgat taatgaaaaa
     7921 gatagtacgg atttgaaatg ggcttcttat accgttctat tccaagtcgt gaaaaactca
     7981 taaagaaatt agtatagaag ttgagggcgt accgataaga agattatcga tacgccctat
     8041 ttttttgccg ttttttttat gtatatgggt aaagatcgta tctttgcgta ctttaagagg
     8101 agtattgtga aatgagatac aagaatttaa taggttttgt ctgggtggcg gttttcatga
     8161 gtctgtttac ttcttgccta aaggacataa ataacgtcta taatccggga acgaccgccg
     8221 ctgtggttcg tcaacatgga gatagcgcgt tgatgatggc taatacccgg ttcggttgga
     8281 tctattcgac gaagctgagc tcatactcag agggtaaatg cttgttggtg agctttgatt
     8341 atgatcctag cttaccggaa aatacgaatg cggaacaaaa agggtattat acggtgacga
     8401 tacaagggga aaccgctgtt aaccagcaaa acgctgagag ccctcttacg gatacgcata
     8461 aattattgac taatgagcaa ccggtacttg cggtcaaccc caatgattct gttttataca
     8521 tcgaattaga agactattta tttctgccct ctgcttgttg gacgacaaaa gatcggactt
     8581 taaattggca attgacttac gatccggctc aggaagctgt tgtggaaaat cgaaaatcta
     8641 tatattcctt atatttacgg gctgccgcta cgaccggaaa gccggaggac aaggcagaag
     8701 aggctatcgc ggttatcaat gcctttaatc tggggaactt tatcaaagat atgcgagaac
     8761 aaggtggacg tgatgcggat atgtatgttc ggattcatta tatcgatcaa attaatccga
     8821 aagatagtac ccagtttaca tggggagtaa cagatccttt acttataaaa taaaaaagat
     8881 gagaaagcga attttatacg gcttattttt atccttgttt ttcttaatga cctcttgtat
     8941 gggggatgga agtaattcca tcaattatca tcgagtagga gtgatacgtg agaatcctat
     9001 gcgatgtatt tacacggcgg atgatcaagg ggagatcttt atcgtctctt cctctgagtt
     9061 tgagaatcgg acggatttga aagatggcga ttgctgtgtg gttgatttca agacgaattt
     9121 tagcgaggaa ttgggcaatg gtgtttacaa cgctgagatt tataagtatg attcggtcgc
     9181 tgtatggcct ttgcatgaga cattgactga tactacggtt gtattggaca aggagcgtct
     9241 ggttacgctg gactttaaga aaagtattta tttggaagga cgtttcttct tgcaaaccca
     9301 acatgtaaat catcaggtag accaaaagga tattttcaat ttatcctata accctgatca
     9361 ggaggtggaa gaagacagca ccggacaacg ggtctataac ctataccttc gggtaaccca
     9421 agagggaggt accggcgatt ccacgaaatg ggtgaatacg accgctttta cgatcgataa
     9481 gtttttggac caagccaaag cgatagagag tagtgagggg caaaatgtga taaattttaa
     9541 aataaattat gccgaacgct ataatgcgga tacaaccgca tgtgtttggg gggctaccga
     9601 cgtatttacg ttgcgtttta cgaattaaat atatac
//
LOCUS       DBMDTB010000127         9525 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_2025_length_9525_cov_12.712755, whole genome shotgun sequence.
ACCESSION   DBMDTB010000127 DBMDTB010000000
VERSION     DBMDTB010000127.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 9525)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 9525)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9525
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2025_length_9525_cov_12.712755"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..501
                     /gene="tpx"
                     /locus_tag="ACZPB4_15060"
     CDS             <1..501
                     /gene="tpx"
                     /locus_tag="ACZPB4_15060"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008379 - thioredoxin peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0016684 - oxidoreductase activity, acting
                     on peroxide as acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HIR1099573.1"
                     /translation="MAKVTLKGNEIHTNGELPKVGTEAPDFKGVKSDLSELSLSDLKG
                     KKVVINVFPSLDTSVCAASVRRFNKEAASHPDTVVLAVSKDLPFAHGRFCTTEGIDKV
                     ITLSVFRCSCFEDKYGMLLVDGPLKGLLARGVIVVDGAGKVVYEELVPEITTEPNYDA
                     ALAALK"
     gene            607..1824
                     /locus_tag="ACZPB4_15065"
     CDS             607..1824
                     /locus_tag="ACZPB4_15065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HIR1099574.1"
                     /translation="MDNWKRVFAIIWTGQFLSILTSSIVNFAIVLWLSLETGSAEVLA
                     FATMAALLPQSVLGLFTGIFIDRWKRKRVMIMADSFIAFCTLILAVLFYFDLAKISHI
                     YVLLALRSVGSAFHMPAMQASVPLLAPKSELMRIAGINQVIQSVCNIAGPALAGLFIT
                     MMKMTNILLLDVAGAAFACLSLCFVFIPDPSHEERNSELHLWREAKEAIMEVRNQYGL
                     SWLFLLSILATFVIMPVSVLFPLMTLNHFAGNAFQVSLVEVSWGGGALLAGALLGLKK
                     YRWNEILLINGMYIALGLTFLFSGLLPVSGFIWFAVLTALGGVCGSLYFATFTTVIQS
                     RIDPGVMGRVFSFYMSFSMLPSMIGLLSTGFLADSIGLGNTFIISGGFLCLIGIISFF
                     IPSLISLKESFKR"
     gene            1852..3135
                     /locus_tag="ACZPB4_15070"
     CDS             1852..3135
                     /locus_tag="ACZPB4_15070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HIR1099575.1"
                     /translation="MNKKILQLAIPSIISNITVPLLGLIDVAIVGHLGSASYIGAIAV
                     GGMLFNIIYWIFGFLRMGTSGMTSQAYGKRDLTEVTRILFRSVGVGFLISLGLLILQY
                     PILKVAFTLIDATEEVKQWASLYFNICIWGAPAVLGLYGFAGWFIGMQNSRFPMFIAI
                     TQNIVNIAASLCFVFVLGMKVEGVALGTLIAQYAGLLMAFALWLKYYKRLKAYIDWNG
                     LWGREAMRRFFSVNSDIFFRTLCLVAVTTFFTSTGARQGDVILAVNTLLMQLFTLFSY
                     IMDGFAYAGEALAGRFIGAKNDVGLRKCIRLLFLWGIGLSLSFTILYALGGKNFLGLL
                     TNDTSVIEASGDYFYWVLAIPLCGFSAFLWDGIFIGATATRQMLYSMLVASGTFFIMY
                     YLFYQSMGNHALWMAFLWYLSLRGGMQWVLWRLKK"
     gene            complement(3187..4893)
                     /locus_tag="ACZPB4_15075"
     CDS             complement(3187..4893)
                     /locus_tag="ACZPB4_15075"
                     /EC_number="1.3.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0006631 - fatty acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HIR1099576.1"
                     /translation="MANFYTDNPSLKHHLHHPLMKRIVELKERGYADKDTYDYAPIDF
                     EDAMDSYEKVLEIVGEICGEIIAPNAEGVDHEGPTVANGRVTYASGTQQNLDAVRKAG
                     LMGIAMPRRYNGLNFPIVPYIMAADLVSRADAGFENLWGLQDCAETLYEFGNEDQRQR
                     YIPRVCDGETMSMDLTEPDAGSDLQSVMLKASYNEADGCWYLNGVKRFITNGDADIHL
                     VLARSEEGTKDGRGLSMFIYDKRNGGVNVRRIENKMGIKGSPTCELVFKNAKAELCGD
                     RKLGLIKYVMALMNGARLGIMAQAVGLSEAAYREAYAYALDRKQFGKSIIEFPAIAEI
                     IALMRAKADASRSMLYETARFVDVYKALDDISKERKLTPEERQEFKKYSKLADAFTPM
                     GKGMTTEYANQNAYDAIQVHGGSGFMKDYACERIYRDARITNIYEGTTQLQVVAAIRH
                     VTTGTYLNQIREYQAIEYKPELEALKNKLAAMTEKYEKVVAKVTETKDNEYIDFQARR
                     MVEAAAHCVFGYLLLQDANKDDSFRRSAEVYVNYGQAEIDKIESFINNFNREDLAYYK
                     QQ"
     gene            complement(4898..5917)
                     /locus_tag="ACZPB4_15080"
     CDS             complement(4898..5917)
                     /locus_tag="ACZPB4_15080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007486135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HIR1099577.1"
                     /translation="MNNVFVYCETEGTNVADVSLELLTKGRKLANQLGCGLEAIVAGS
                     GLEGVEKQVLPFGVDKVHVFDAPGLFPYTSLPHSSILINLFKEEKPQICLMGATVIGR
                     DLGPRVSSALTSGLTADCTSLEIGSHEDKKAGITYENLLYQIRPAFGGNIVATIINPE
                     HRPQMATVREGVMKKEVLDENYKGEVIHHDVAKYVPETDYVVKVIDRHVEKAKHNLKG
                     APIVVAGGYGVGSKENFNLLFDLAKELHAEVGASRAAVDAGFCDHDRQIGQTGVTVRP
                     KLYIACGISGQIQHIAGMQDAGIIISINNDENAPINTIADYVINGTVEEVIPKMIKYY
                     KKNSK"
     gene            complement(5922..6827)
                     /locus_tag="ACZPB4_15085"
     CDS             complement(5922..6827)
                     /locus_tag="ACZPB4_15085"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010539018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HIR1099578.1"
                     /translation="MSLRIIVLAKQVPDTRNVGKDAMKADGTINRAALPAIFNPEDLN
                     ALEQALRLKDAYPGTTVTLLTMGPGRAAEIIREGLYRGADGGFLLTDRAFAGADTLAT
                     SYALATAIKKINDYDIIIGGRQAIDGDTAQVGPQVAEKLGLTQITYAEEILNVDKEAG
                     RITVKRHIDGGVETVEGPLPIVITVNGSAAPCRPRNAKLVQKYKHAMGKQERAVQPAC
                     HQDGTPTLRYPELYETRPYLDIQEWSVADVNGDLVQCGLSGSPTKVKAIENIVFQAKE
                     SKTISSADQEVEDLIVELLANHTIG"
     gene            complement(6914..7465)
                     /locus_tag="ACZPB4_15090"
     CDS             complement(6914..7465)
                     /locus_tag="ACZPB4_15090"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099579.1"
                     /translation="MEETFKRIPPEDVFITVFKRKPTEEELWMGVPPDFDGNRPSGNN
                     LIDLFAYLIRKYGRMDTSEYARIMQLKTSELRGAILAIGGMSAMARMAQPLPSPRSSG
                     ADGADGHEHHRDRRQAGFLAALGILQVLPHADEIAALGMAHREKKTGLKPEENLSLLR
                     VISRQYMLKHTPSVQFPPQSSLL"
     gene            complement(7649..9028)
                     /locus_tag="ACZPB4_15095"
     CDS             complement(7649..9028)
                     /locus_tag="ACZPB4_15095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HIR1099580.1"
                     /translation="MTTKKQEKIKFSKAFWVANTVELFERAAYYGVFIVITLYLSRIL
                     GFNDIQAASIAGIFSACLYLLPTFAGALADKIGFRNSMLLAFTLLTCGYLGLAVYPTW
                     LQSAGLVEYSTTTTFTGLLESNLQYGIIPIMALIVCGGAFIKSVISGTVAKETTPETR
                     AKGFSIFYAMVNIGAFSGKTIVKPLREALGNEGLITLNYFSASMTFLALLAIWFFYKS
                     AQHSGEGKTFGQIWNALIKVCSNGRLLILILIITGFWMVQHQLYATMPKYVLRLAGEG
                     ASPSWYANVNPLVVVLTVNLVTQMMRKRTALTSMTVGMFIMPVSALCMASGNMLDGNT
                     NILGMHPVAFMMVVGIVFQGLAETFISPRFLEYFSLQAPKGEEGLYLGFSHLHSFLSS
                     IFGFGLSGFLLSKYCPEPTLFASHEEWLAASANAHYIWYYFGAIALVSAVALIVYGQV
                     VKRLDSQKI"
     gene            complement(9140..>9525)
                     /locus_tag="ACZPB4_15100"
     CDS             complement(9140..>9525)
                     /locus_tag="ACZPB4_15100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008771676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099581.1"
                     /translation="GPDSHAKWMVRQEWNKWNIDAFFPMNYNDFYLENASWLAPIVKE
                     EVASVQGKKPVYSGLFICEDWQNKANIKDPEGHGLIPSEIEEAVRGSMENGAAGVALF
                     TPGNMTDEHWKAFDKAIHQPYTVKP"
BASE COUNT         2205 a         2203 c         2419 g         2698 t
ORIGIN      
        1 atggcaaaag taacattaaa aggtaacgag attcatacga acggcgagtt gccaaaagtt
       61 gggacagagg ctccggactt taagggtgta aaaagtgatt tatccgaatt gtcgctaagc
      121 gacttgaaag gaaagaaagt ggtgataaat gtttttccga gcttggatac aagtgtatgt
      181 gcggcatcgg taagacgctt caataaagaa gccgcttcgc atccggatac agtggtatta
      241 gctgtttcta aagatttacc ttttgcgcat ggacgtttct gtactacgga aggtattgat
      301 aaagtgatta cattgtcagt gttccggtgt tcatgttttg aggataagta tgggatgctt
      361 ctggtagacg gtccgctgaa agggttatta gcccgtggcg tgatagtggt cgatggagct
      421 ggtaaggtgg tttatgagga acttgttccc gagattacta ccgaaccgaa ttacgatgcg
      481 gctttagctg cattgaaata aatgtagtag attattgttt ttcattggtt aaagttaagg
      541 gttagtgtag gaggccgtcg gatgtgaatc ccgcggcctt cgttttttta atacaaacac
      601 gtttatatgg ataactggaa gcgagtattt gccattattt ggacggggca gttcttatct
      661 atactgacaa gttcgattgt taatttcgcg atagtcttgt ggttgagtct ggagacaggt
      721 tccgctgagg tattggcatt tgctacgatg gccgctttgt tacctcaatc tgttttgggg
      781 cttttcacgg ggatctttat cgaccggtgg aaaaggaagc gggtgatgat tatggcagat
      841 agctttattg ctttttgtac gttgatattg gcggtcttgt tttattttga tttggctaag
      901 attagtcata tatatgtgtt attggccctt cgttccgtag gttctgcctt tcatatgccc
      961 gctatgcaag cttctgttcc tttgctggct ccaaaatcgg agttgatgcg catagctggg
     1021 attaatcagg tgatccagtc ggtgtgtaat atcgccgggc ccgctttggc cggtctattc
     1081 ataacgatga tgaagatgac gaatatcctc ttattggatg tggctggagc ggcgttcgct
     1141 tgtctatcgc tctgctttgt ctttattccc gatccttctc atgaggaacg aaattcagaa
     1201 ttgcatcttt ggagagaggc gaaagaggcg attatggaag tccgtaacca atatgggcta
     1261 tcgtggttat tcctattgtc tatattggct acattcgtga ttatgccggt aagtgtctta
     1321 ttcccgttga tgacgttgaa tcattttgcc ggaaatgctt tccaagtgag cttggtcgag
     1381 gtttcatggg gtggaggagc cttgcttgcg ggtgctttac tggggcttaa gaaatatcgt
     1441 tggaatgaga tcctgttgat taatgggatg tatatagcgt tgggattgac attcttgttt
     1501 tccgggttgt taccggtatc cggttttatc tggtttgcgg tgctgacggc tttaggaggt
     1561 gtttgtggtt ccctgtattt tgctactttt actacggtta tccaatctcg cattgatccg
     1621 ggagttatgg gaagggtatt ctctttttac atgagcttta gtatgcttcc ttcgatgatc
     1681 ggtcttttga gtaccggctt tttggcggat tctatcgggc ttggaaatac ctttataata
     1741 agtgggggct ttttatgttt gataggtatt atatcctttt ttatcccttc gttgatcagt
     1801 ctgaaagaga gttttaagag ataacgatat cgtatttaga cactatttaa tatgaataag
     1861 aaaatacttc aactggcgat accttctatt atttccaata taaccgtacc tttattggga
     1921 ttgatagatg tggcgatcgt gggacatctt ggatctgctt cgtacatcgg ggcgatcgct
     1981 gtaggcggga tgctgtttaa tattatctac tggatattcg ggtttctccg tatggggaca
     2041 agcggtatga cttcccaagc gtacgggaaa cgggatttga cggaagttac ccggatctta
     2101 ttccggtctg tcggggttgg tttcctgata tctttggggc ttttgatact tcaataccct
     2161 atcttgaagg ttgcgtttac tttgatcgac gcaacggagg aggtaaaaca atgggcctct
     2221 ctctatttta atatctgtat ctggggagcg ccggctgtat tggggttata tggctttgcc
     2281 ggttggttta tcggtatgca gaattctcgt ttcccgatgt ttatcgctat cacgcagaat
     2341 atcgtgaata ttgcggccag cctatgtttc gtgtttgtgc tgggtatgaa ggtggaaggc
     2401 gtagcgttgg gaacactgat cgcccaatat gcgggtctcc tcatggcgtt tgctctttgg
     2461 ttgaaatatt ataaacgttt gaaagcgtat attgattgga acgggctttg gggtagggag
     2521 gcgatgcgtc gcttcttctc agtcaatagt gatatatttt tccggacctt gtgcttggtc
     2581 gctgttacga ctttctttac ttctacaggt gcgagacaag gggatgtgat attagccgta
     2641 aacaccttgt tgatgcagtt atttaccttg ttctcttata taatggatgg attcgcttat
     2701 gcgggagagg cattagccgg tcgctttatt ggagccaaaa acgatgtggg gttacgtaaa
     2761 tgcattcgct tattgttcct atggggaatc ggcctctcat tgtctttcac gatcctttat
     2821 gcgttgggag ggaagaattt tctgggatta ttgacgaacg atacctcagt cattgaagct
     2881 tccggggatt atttctattg ggtgttggcg attcctttat gtggattctc cgctttcctt
     2941 tgggacggta tctttatcgg tgccacggcc acacgccaga tgctttactc gatgcttgtg
     3001 gcctcgggca ctttctttat tatgtattac ttgttttatc aatcgatggg gaatcatgcc
     3061 ttatggatgg ctttcctttg gtatctgtct ttacgtggcg gtatgcaatg ggtactttgg
     3121 cggttaaaaa aataaggcga gaacctgtaa ctgatcctcg cctcatttta tcctaggaaa
     3181 acctatttac tgttgtttgt aataagctaa gtcctcacga ttgaagttgt tgatgaagga
     3241 ttcgatctta tcaatctcag cttgtccgta gtttacataa acctcggcgg aacggcggaa
     3301 gctgtcatct ttgtttgcgt cttgcaatag caagtagccg aatacgcaat gagcggctgc
     3361 ctcgaccata cggcgagctt ggaagtcaat atattcgtta tcctttgtct ccgtaacctt
     3421 ggctaccact ttctcatact tctcggtcat agcggcaagt ttgttcttca gagcctctaa
     3481 ttccggctta tactcgatcg cttggtattc acgaatctgg ttcaagtaag tacccgtggt
     3541 gacgtggcgg atggccgcta cgacttgcaa ttgggtggta ccctcataga tattcgtgat
     3601 gcgggcatcc cggtagatac gttcgcaagc gtagtctttc atgaaaccgg aacctccgtg
     3661 aacttggata gcgtcgtaag cgttctggtt tgcgtactcg gtagtcatgc ctttacccat
     3721 cggggtgaaa gcatccgcga gcttgctgta cttcttgaat tcttgacgtt cttccggagt
     3781 cagtttacgt tccttggata tatcatccaa cgctttgtag acgtcaacga aacgggcggt
     3841 ctcgtataac atagaacggg aagcatccgc tttcgcacgc atcaaggcga taatctcagc
     3901 gatcgccggg aactcgatga tagacttacc aaactgttta cgatccaagg cgtaagcata
     3961 agcctcacga taggcagcct cgctaagtcc tacggcttga gccatgatac ccagacgggc
     4021 accgttcatc aaagccatta catatttgat caaacctagc ttacgatcac cgcaaagctc
     4081 ggctttcgcg ttcttgaata ccaactcgca agtaggagag cctttgatac ccattttgtt
     4141 ctcgatacga cggacattca cgccaccatt gcgcttgtcg tagatgaaca tggaaaggcc
     4201 acgtccatcc ttcgtacctt cctcggaacg ggccaatacc aaatggatgt cagcgtcgcc
     4261 attcgtgatg aaacgcttta cgccgttcag ataccagcaa ccgtcagcct cgttgtaaga
     4321 agctttcaac ataacggatt gaaggtcgga acctgcgtcc ggctccgtca agtccataga
     4381 catggtctct ccgtcgcaaa cacgagggat gtaacgttgg cgttgatcct cgttgccgaa
     4441 ctcgtataag gtctcggcac aatcctgtag gccccaaagg ttctcgaaac cggcgtcggc
     4501 acgggaaacc aagtcggcgg ccatgatgta agggacgatc gggaaattca acccattgta
     4561 gcggcgaggc atagcgatac ccatcaagcc ggccttgcga acggcatcga ggttttgctg
     4621 tgtcccggaa gcgtacgtga cgcgtccgtt cgctaccgtg gggccctcat ggtctacgcc
     4681 ctcagcgttc ggggcgataa tttccccgca aatctcacca acgatctcca atactttctc
     4741 gtagctatcc attgcgtcct caaaatcgat cggagcataa tcgtatgtat ccttgtcggc
     4801 atagccgcgc tctttcagct ctacgatacg cttcatcaac ggatggtgaa gatgatgctt
     4861 caagctggga ttatctgtat agaaattagc cataatctta cttactgttc tttttgtaat
     4921 acttaatcat cttaggaatc acctcttcta ccgtaccatt gattacgtaa tcggcgatcg
     4981 tgttgatcgg ggcgttctca tcattattga tcgaaatgat gataccggcg tcttgcatgc
     5041 cggcgatatg ctggatctgc ccggagatac cgcaagcgat atataatttc ggacgcaccg
     5101 tgacaccggt ctgaccgatc tgacggtcgt ggtcgcagaa accggcatcg acagccgcac
     5161 ggctggcacc tacctcggcg tgaagctctt tcgccaaatc gaacaataaa ttaaagttct
     5221 ccttagagcc tacgccataa cctccggcta ctacgatcgg agcgcctttc aggttgtgct
     5281 tcgctttctc tacatgacgg tcgatcactt tcaccacata gtctgtctcg gggacatact
     5341 tcgctacgtc gtggtggatc acttcgcctt tatagttctc gtccaaaacc tcctttttca
     5401 tcacgccctc acgaacggtc gccatttgcg ggcgatgttc cgggttgatg atcgtggcta
     5461 cgatgttacc accgaacgcc ggacggatct gatataataa gttctcgtag gtgatacccg
     5521 ctttcttgtc ctcgtgcgag ccgatctcca aagaggtaca atcggccgtc aagccgcttg
     5581 tcaaggccga ggatacacga gggcccaagt cacgaccgat caccgtagcg cccatcaagc
     5641 aaatctgcgg tttctcctcc ttgaacaaat tgatcaagat agaggaatga ggaagtgacg
     5701 tataagggaa cagacccgga gcgtcgaaca catgaacctt gtcgacgcca aaaggcaata
     5761 cttgtttctc tacaccctca aggccggacc cggcaacgat cgcctccagc ccacagccta
     5821 attgattggc tagcttacga cctttggtca gaagctcaag acttacatcg gcaacgttcg
     5881 tgccttctgt ctcacaatat acaaatacgt tgttcataat cttatccgat ggtgtggtta
     5941 gctaacagtt cgacaatcaa atcctctact tcttggtcgg cgctggagat ggtcttgctt
     6001 tccttggctt ggaagacgat attctcgatc gcttttacct tcgtcggcga accgctaagg
     6061 ccgcattgaa ccaagtcacc attcacgtcg gctacgctcc attcttgaat atccaaatac
     6121 gggcgggtct cgtacaattc cgggtagcga agagtcggcg taccgtcctg gtgacaggcg
     6181 ggttgcacgg cccgttcctg tttacccatg gcgtgtttgt acttttgtac caacttcgcg
     6241 ttgcggggac ggcagggagc ggcggagccg ttcacggtga taacgatagg aagcggacct
     6301 tccacggtct caacaccccc gtcgatatga cgttttacgg tgatacgtcc ggcctcctta
     6361 tcaacgttta ggatttcctc ggcatacgtg atctgggtca gtcctaattt ctcagcgact
     6421 tgcggaccta cctgtgccgt atcgccgtcg atcgcttggc gaccaccgat gataatatca
     6481 taatcgttga ttttcttgat agccgtggca agcgcatagg atgtggctaa cgtgtcggct
     6541 ccggcaaacg cacggtcggt caacaaaaaa ccgccgtcag caccacgata caaaccctcg
     6601 cggatgattt cggcggcacg tcccgggccc atcgtcagca gcgtaactgt cgtcccgggg
     6661 taagcgtctt tcaagcgtaa cgcttgttcc aacgcgttca ggtcttccgg gttaaagatc
     6721 gcgggcaagg cggcgcgatt gatcgtaccg tccgccttca tggcgtcctt tcccacgttt
     6781 cgtgtatccg ggacctgttt cgctaaaact ataattctta aactcatatt atataggaat
     6841 attagatttt tatattgatg taatacttct actttcttgt taatctcgag gtgcaaaagt
     6901 aatcaaacat tctttataac aaagaacttt gcggaggaaa ttgcacactt ggcgtgtgtt
     6961 tgagcatgta ttgcctgctg attactcgta gcaatgatag gttctcttcc ggtttgagcc
     7021 cggttttttt ttctcgatgc gccattccca aggctgcgat ttcgtcagcg tgcggaagaa
     7081 cttggagaat accgagggct gcgagaaacc cagcttggcg gcgatcgcgg tgatgctcat
     7141 gtccgtccgc tccatcagct cctgagcttc gaggagaagg tagcggttgc gccatcctcg
     7201 ccatcgccga catgccgccg atggcgagga tggcgccccg gagctcgctg gtcttgagtt
     7261 gcattatgcg ggcgtattcg ctggtgtcca tccggccgta cttgcggatg agataggcga
     7321 agagatcgat caggttgttg cccgaggggc ggttgccgtc gaagtcggga gggacgccca
     7381 tccaaagctc ttcttcggtg ggtttacgct tgaagacggt gataaagaca tcttccgggg
     7441 ggattctctt gaatgtttct tccatgatga tatgttttaa ggttgttttt tctcaaggat
     7501 ttgatcttgc gattcttccg gatcaaatct acggattatg attggatatc gcaagcctta
     7561 aaggtcaaat ccatgtgttt ggattagata ttttagaact acgaggtcaa attaaaggtg
     7621 gtagatttga ccccgtagtt ttatcgggtc aaatcttttg gctatccagc ctctttacga
     7681 cttgtccata cacgatcaac gctacggcgg ataccaaggc gatcgcgccg aagtaatacc
     7741 agatgtaatg ggcgttcgcg cttgccgcca gccattcctc gtgagaggcg aacagggttg
     7801 gctccgggca atacttgctt aaaaggaaac cggatagccc gaatccgaag atagaggaga
     7861 ggaaagaatg caaatggctg aatccaagat agagaccttc ttctcctttg ggtgcttgca
     7921 aggagaaata ctcgagaaag cgaggggaaa tgaacgtctc cgccagccct tggaagacaa
     7981 tacctactac catcatgaaa gctacgggat gcatgcccag tatattcgta ttcccgtcca
     8041 gcatattccc ggatgccatg caaagggcgg acaccggcat gataaacata ccgaccgtca
     8101 tggaggtgag cgctgtccgc ttccgcatca tctgcgtgac cagattgacc gtaagcacga
     8161 cgaccagcgg gtttacgttg gcgtaccaag aaggagaggc cccctcgccg gccagccgaa
     8221 gcacgtattt aggcatcgtg gcatacagct ggtgctgaac catccaaaag cctgtaatga
     8281 tgaggatcaa gatcaataac cgtccgttac tacaaacctt gatcaaggcg ttccagatct
     8341 gcccgaacgt cttgccctcg cccgaatgct gagcgctttt gtagaagaac cagatggcta
     8401 gcaaggcaag gaaggtcatg ctcgccgaga aatagttcaa ggtaatcaaa ccttcgttgc
     8461 ccaacgcctc acgaagcggc ttcacgatgg tcttcccgga gaaggccccg atatttacca
     8521 tcgcgtagaa gatagagaag cccttcgcac gggtttccgg cgtagtctct ttagcgaccg
     8581 tgccggagat aacgctcttg ataaaagccc cgccgcatac gatcaaggcc atgataggga
     8641 taatgccgta ctgaagattg ctctccagca atcccgtaaa ggtagtcgtc gtgctgtatt
     8701 caacaagtcc ggcggattga agccaagtag ggtaaacagc cagtcctaga taaccacaag
     8761 ttaacaaagt gaaagccagt agcatcgagt tgcggaaacc gatcttatcg gccaacgctc
     8821 cggcgaatgt gggcagcaga tacaaacagg cggaaaagat tccggcgatg ctggcagcct
     8881 gaatgtcgtt aaagcctaag atgcggctaa gataaagggt gataacgata aatacgccat
     8941 aataagcggc tcgctcgaac aactcgacgg tgttcgccac ccagaatgct ttactgaact
     9001 tgattttctc ttgtttctta gttgtcatga tatttttatt agtaagatag attagatgga
     9061 taagtaaaag aggaggcgca ggtgagaaaa tgaagagctg cgcctccttg tctttgtttt
     9121 atcgtatagt aattacgaat tagggcttta cggtatacgg ttggtggatc gccttatcga
     9181 aagctttcca atgttcatcc gtcatgttgc ccggcgtaaa caacgccacg ccagccgctc
     9241 cgttttccat ggagcctctt acggcctcct cgatctcgga cgggatcagt ccgtggcctt
     9301 ccgggtcctt gatattcgcc ttgttctgcc aatcctcgca gatgaacaaa ccgctataaa
     9361 ccggcttctt gccttgcacg gaggctactt cctctttcac gatcggagcc agccaagaag
     9421 cgttctccag atagaaatcg ttataattca tcgggaagaa agcgtcgata ttccatttat
     9481 tccattcttg acgaaccatc cacttggcgt gagagtccgg ccccg
//
LOCUS       DBMDTB010000128         9449 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_2041_length_9449_cov_10.717587, whole genome shotgun sequence.
ACCESSION   DBMDTB010000128 DBMDTB010000000
VERSION     DBMDTB010000128.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 9449)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 9449)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9449
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2041_length_9449_cov_10.717587"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..1425
                     /gene="ilvD"
                     /locus_tag="ACZPB4_15105"
     CDS             <1..1425
                     /gene="ilvD"
                     /locus_tag="ACZPB4_15105"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004160 - dihydroxy-acid dehydratase
                     activity [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009097 - isoleucine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009099 - L-valine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HIR1099582.1"
                     /translation="IHVKATPFDAGVFIASCDKSVPAHLMAIARLDMPAIFMPGGIMK
                     AGPNLLTLEQIGTYSAQYERKEITEEQFMVYKRDACPDCGACSFMGTASTMQVMAEAL
                     GIALPGSALIPAHLPELKETARKAGEHALGRAKEELKPSDIMTIQAFENAIMVHAAIA
                     GSSNSLLHLPAIAHELGIQLSPDLFDKIHRKIPYLLNIRPSGFWPGEYFWYAGGVPAI
                     MKEIKEFLHLDVKTVTGRTLGENLKDLQLNGFYENCHKYLPALGVKVGDIIKPLHTPI
                     KAQGAIAILKGNLAPEGAVVKHSAISPRLMQVTLKARVFDCEENAIEAVLQKKIHPGE
                     AVFIRYEGPKGSGMPEMFYTTEAIASDPELVETIALITDGRFSGATRGPAIGHVSPEA
                     SEGGPIALVENDDLIRIDIPARRLDIIGTGGIERSAEEIEKILSERRAHWIKPESQYK
                     KGILDIYTHNSVSPMKGAYMEFFM"
     gene            1448..2479
                     /locus_tag="ACZPB4_15110"
     CDS             1448..2479
                     /locus_tag="ACZPB4_15110"
                     /EC_number="2.7.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HIR1099583.1"
                     /translation="MMRKNISILVSLLILSLTACSDKGQYFEESGSVFHTSYHIKYKA
                     KQILTDKIDSELQRFNLSLNPFNPNSTIAKVNNNEDVEVDEWFTEVFIKAEEISKKSG
                     GAFDITCAPLINLWGFGFSKMDSVTPQMIDSIKAFVGYQKVRLEGKKIIKEDPRILLN
                     CSSIAKGYACDVIARLLEKEGVKNYMVEIGGEVTMKGVNQQGDCWRVGINKPEIGTSG
                     VTNDVEEIVQLCQKGGVATSGDYRNFYIKDGKKYAHTINPATGYPAGQNILSATIVAE
                     DCMTADAYATTFMVLGVEKAKLLAQSIPQIEYFIIYADNNGQQKVTYSKGMLEYLPNR
                     KTLAILENP"
     gene            2488..2865
                     /locus_tag="ACZPB4_15115"
     CDS             2488..2865
                     /locus_tag="ACZPB4_15115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic nucleotide-binding domain-containing
                     protein"
                     /protein_id="HIR1099584.1"
                     /translation="MKRYLNQLECKILRAGDSLFNSTTTDNLLIFVFSGKLIIYSQEG
                     THIAEVAKDHFMLLAQNTNHKVIASAPTRLILIHAGSLSDMIINDPEWNVEKPVVLPI
                     PPALAHTLNQIEYYMKDKYFTLN"
     gene            complement(2868..3449)
                     /locus_tag="ACZPB4_15120"
     CDS             complement(2868..3449)
                     /locus_tag="ACZPB4_15120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maf-like protein"
                     /protein_id="HIR1099585.1"
                     /translation="MLENLKKYKIVLASNSPRRRNLLSGLDIDFEVRVISDIDESYPD
                     SIDSMEIPLYIARSKAEAYKPTMADDELLITADTIVWTFDGVMGKPANREEAYAMLHA
                     LSDHVHQVITGVCIMTKDKNVGFSVESAVCFAKLGDEEINYYLDKYKPYDKAGGYGIQ
                     EWIGYIGVEAINGSFYNVMGLPVQKLYQELKHF"
     gene            complement(3487..4008)
                     /locus_tag="ACZPB4_15125"
     CDS             complement(3487..4008)
                     /locus_tag="ACZPB4_15125"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008158604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="KdsC family phosphatase"
                     /protein_id="HIR1099586.1"
                     /translation="MSSINYDLRKIKAFVFDVDGVLSCDVIPLHPNGDPMRTVNIKDG
                     YALQLAVKKGYEVAIITGGYTEAVQIRFSRLGIQRIYMRSAVKVHDFKDFMEKTGLSP
                     EQIMYAGDDIPDYEVMTQVGLPVAPADAAPEIKEIAKYISSRRGGEGVARDVIEQTMR
                     AQGHWFGEEAFGW"
     gene            complement(4001..4768)
                     /locus_tag="ACZPB4_15130"
     CDS             complement(4001..4768)
                     /locus_tag="ACZPB4_15130"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011965916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rossmann-like and DUF2520 domain-containing
                     protein"
                     /protein_id="HIR1099587.1"
                     /translation="MRVVFVGAGNLATRLSLEMRKSGMSIGQVYSHTSEHAKILADEL
                     GCGWTVIPEEIVEDADLYVFSLKDAVLQDVIARVKPNNGLWVHTAGSMPISVFEGFTA
                     RYGVVYPLQTFSKSREVDFKKIPFFLEANSSEDEKVLGEVARALSCDVRFLSSEKRKN
                     LHLAAVFACNFTNHMYALAEKILEEQQIPGEVLLPLIDETAAKVHVMSPARAQTGPAI
                     RYDENVINKHMAMLKDPDMRNLYELISRSIHKEARHE"
     gene            complement(4765..5325)
                     /locus_tag="ACZPB4_15135"
     CDS             complement(4765..5325)
                     /locus_tag="ACZPB4_15135"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HIR1099588.1"
                     /translation="MESFATLIQNRRSTRKFTEQLLSPEQVELILKAALMAPASKRSN
                     PWQFVVVEDKEMLKKLAGCKKNGSTFLEGCALAVVVLANVMESDVWIEDASVASIYMQ
                     LQAEDLGLGSCWCQIRNRVTEDEADSNNYVRSLLDIPYQLDVLSIIGIGYKDQVRKPF
                     DESHLQWEKIHIGKFSLPEENKETGE"
     gene            5447..7858
                     /locus_tag="ACZPB4_15140"
     CDS             5447..7858
                     /locus_tag="ACZPB4_15140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011965914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HIR1099589.1"
                     /translation="MKIRAIAALLFILISVSAFGEGRIKITGYVRDADGNPLELVNVR
                     VKNTLIGSMTNEKGYYSFSISPGDSISIIYSCLGYNKAERIIPSAQADMRLNVQMNYT
                     SFDLGEVSVTAIRKQTTTMESLNADKIKLLPDPSGGSIESLVVTFAGVSSNNELSSQY
                     SVRGGSYDENIVYVNGIEVFRPLLIRSGQQEGLSFINPDLTEAVNFAAGGFEARYGDK
                     MSSVLDITYKKPKIFEGSASASLLGANAYVGSSIGKFTQVTGFRFKSGRSILGTMDTD
                     AEYDPKFIDLQTYITYQLAPKWEINFLGNLANNNYKFTPYSRETSFGTAEHPKNFKVY
                     FDGRERDRFQTLFGALTLKHNPNENTELGLQASAFKSKEEEGYDIAGEYWLSENGAEN
                     PNDDASAAMSVGRYHEHARNRLNSTVMNVGHYGMARLLNNTLKWGATVQMEKINDKIS
                     EWEKRDSSGYSLPQTGNNVSVYSNLFSDNQIESTRFSAYAQDAFKFRTKQGLFTLVAG
                     VRGSYWTYNKEFLFSPRASLGFIPNFDQDLTLRFATGLYYQSPFYKELRRVDKDKNGN
                     NITVLNKDLKSQRSIHFILGGDYTFRAVDRNFKVTAEMYYKKLDNLNPYTVDNVKIRY
                     YGENCAKGYAMGLDVKFFGEFVPGTDSWISFSLMKAQQTIRETTTVPMANSQGYNISL
                     FFQDYFPGYKRVKLNLKGVLSGGLPQTIPGKGYEAGYFRTPAYKRVDIGLSYQLAGGT
                     DAIMDRGFFRHLKNIWLGLDVFNILDIKNVSSYYWITDVYNVQYAVPNYLTGRQLNVR
                     LIVDF"
     gene            7987..8397
                     /gene="mce"
                     /locus_tag="ACZPB4_15145"
     CDS             7987..8397
                     /gene="mce"
                     /locus_tag="ACZPB4_15145"
                     /EC_number="5.1.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylmalonyl-CoA epimerase"
                     /protein_id="HIR1099590.1"
                     /translation="MELTHIEHLGIAVKSIEACLPYYEGVLGLKCYNIEVVADQKVKT
                     AFFKVGQTKIELLEPTSEDSTIAKFIEKKGEGIHHIAFAVPDVQAALNEAEEKGVKLI
                     DKAPRGGAEGLNIAFLHPKSTCSVLTELCMPGNK"
     gene            8434..>9449
                     /locus_tag="ACZPB4_15150"
     CDS             8434..>9449
                     /locus_tag="ACZPB4_15150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009128927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA carboxylase subunit beta"
                     /protein_id="HIR1099591.1"
                     /translation="MSNQLEKVKELIALREQARLGGGEKRIESQHKKGKYTARERIAM
                     LLDEGSFEEFDMFVQHRCTNFGIEKTKYLGDGIVTGYGTIDGRLVYIFAQDFTVFGGA
                     LSEALAMKICKVMDQAMKMGAPVIGLNDSGGARIQEGVNALAGYAEIFQRNILASGVV
                     PQISGIFGPCAGGAVYSPALTDFNIMTRGTSYMFLTGPKVVKTVTGEDVTQEQLGGAS
                     VHTTKSGVAHFAVDTEEDGLQLIRKLLSFLPQNNLEETPLVECKDPIDRLDDVLNDII
                     PDNANQSYDMYEVIGTIVDNNEFLEVHADYAKNIIVGFARFNGQSVGIVANQPKVMAG
                     CLDS"
BASE COUNT         2782 a         2224 c         1997 g         2446 t
ORIGIN      
        1 attcatgtaa aagcgactcc tttcgacgct ggtgtcttta tagccagttg cgacaaatcc
       61 gtccctgcgc atttgatggc gatagcccgg ctagatatgc ctgctatatt catgcccggt
      121 ggtataatga aagccggtcc caacctactc acgttagaac aaatcggtac ctatagcgcc
      181 caatacgagc gaaaggaaat aacggaagaa caattcatgg tttataagcg tgacgcatgt
      241 ccggattgtg gagcttgctc tttcatgggt accgcctcca cgatgcaagt aatggcagaa
      301 gcgcttggca tcgctttacc gggctccgcc ttgatccccg cccatttacc cgagttaaaa
      361 gaaaccgccc gtaaagccgg agaacatgca ctcggacggg cgaaagaaga gttaaaaccc
      421 tccgatatca tgacgataca agcgtttgaa aatgcgatca tggtacatgc cgccatagcg
      481 ggttccagca acagcctgct tcatcttcca gctatcgccc atgaactggg aatccagtta
      541 tcaccggatt tgttcgacaa gatacatcgt aagatcccct accttttaaa tatacgtccc
      601 agcggttttt ggcccggcga atatttctgg tatgcgggag gcgtaccggc gatcatgaaa
      661 gaaatcaagg aattcctcca tctcgatgtc aagaccgtta ccggcagaac attgggagaa
      721 aacttaaaag atttacagct caacggcttc tatgagaatt gccataaata tcttcctgcc
      781 ctaggagtaa aggttggcga tattatcaaa cctcttcaca caccgatcaa ggcacaagga
      841 gccatcgcta tattgaaagg aaatttagcg cccgaagggg cagtcgtaaa acattcggcg
      901 atttcacccc gcttgatgca agtcaccctg aaagcgaggg tattcgattg tgaggagaac
      961 gctattgagg cggtattaca aaagaaaatc cacccgggag aagcggtatt tatccgttat
     1021 gaaggaccga aaggaagtgg aatgccagaa atgttttata cgacagaagc gatcgcctcc
     1081 gatcctgagt tggtagagac catcgcattg atcaccgacg gtcgtttctc cggagcgacc
     1141 cgaggcccgg cgatcggaca tgtatccccg gaggcttccg aggggggacc gatcgccttg
     1201 gtagagaacg atgacttgat ccgtatcgat attccagcga gaagattgga tataatcggt
     1261 accggcggta tcgagagaag cgcggaagaa atagaaaaga tcctatccga aaggcgtgca
     1321 cattggataa aaccagagtc acaatataaa aaaggaatcc ttgatattta tacacacaat
     1381 agcgtctccc ccatgaaagg ggcatatatg gaatttttta tgtaagttcg cgacataaaa
     1441 tttcataatg atgcgcaaga atatttccat attagtcagc ctgttgatct tatcgcttac
     1501 ggcttgctcg gacaagggcc aatatttcga agagagtggt tctgtttttc atacaagtta
     1561 ccacatcaaa tacaaggcca agcaaatcct aaccgataag atcgacagcg agctgcaacg
     1621 ttttaacctc tccttaaatc ctttcaaccc caactccacg atcgctaaag tcaataataa
     1681 cgaggatgtg gaggtagatg aatggtttac cgaagtattc attaaggcgg aagaaatctc
     1741 caaaaaatca ggaggagctt ttgatattac ttgcgctcca ttaattaatc tatggggatt
     1801 cggattcagt aagatggaca gcgtaacccc gcagatgatc gatagcatca aggctttcgt
     1861 cggttatcaa aaagtaagat tggaaggaaa gaaaatcatc aaagaagatc cccggattct
     1921 attgaattgt tcgtccatcg caaaaggtta tgcttgcgat gttatcgccc gcctgctgga
     1981 aaaagaaggc gtaaagaact acatggtaga aataggtggt gaggtcacca tgaaaggcgt
     2041 aaatcaacaa ggtgactgtt ggcgagtcgg catcaacaag ccggaaatag ggacaagtgg
     2101 cgtaacaaat gatgttgaag agatcgtaca attatgccaa aaaggggggg tggctacttc
     2161 tggtgactac cgaaacttct acatcaagga tggtaagaaa tatgcccata cgatcaatcc
     2221 tgcgaccggt tatcccgctg gacaaaatat tcttagtgcg acaatcgtgg cggaagattg
     2281 tatgacagca gacgcttacg ctacgacttt catggttttg ggagtcgaga aagcgaagct
     2341 actggcacaa tccatccccc aaatagagta tttcattatt tatgcggaca acaacggaca
     2401 acagaaagtc acctactcaa aaggtatgtt ggaatacctt cctaacagaa aaacattggc
     2461 tatcctcgaa aatccttaag ttcctacatg aagcgttatc taaatcaact tgaatgcaaa
     2521 atactgagag ccggagattc cctgtttaat tccacaacca cggataacct attaatcttc
     2581 gtattttcgg gaaaacttat tatttacagc caagaaggga cacatatagc ggaagtggca
     2641 aaagatcatt tcatgctact tgcgcaaaac accaatcata aggttatagc ctcagcccct
     2701 acccgcctta tcttaataca tgcgggcagt ctatccgaca tgatcataaa tgacccggaa
     2761 tggaatgtgg agaaaccggt cgtcttaccg attcccccag ccttagcgca cacattaaat
     2821 cagatagaat attatatgaa ggataaatac tttaccttga attgagatta aaaatgtttc
     2881 aattcctgat aaagcttttg cacaggtaat cccatcacgt tataaaaact accattgata
     2941 gcctctaccc cgatataacc gatccactcc tgaatgccat accctcccgc tttatcataa
     3001 ggtttatatt tatccaaata ataattaatc tcttcatcac ccaatttagc gaaacaaacc
     3061 gcagattcga cggaaaagcc tacatttttg tccttcgtca tgatacaaac accggttatt
     3121 acctgatgta catgatccga caaagcatga agcatagcat aagcttcctc tcgattcgca
     3181 ggctttccca taaccccgtc aaacgtccaa acgatcgtat ctgccgtgat tagcaattca
     3241 tcatccgcca tagtcggttt ataggcctcc gctttcgaac gggcaatata taaagggatc
     3301 tccatggagt caatagaatc cgggtaagac tcgtcaatat ccgaaattac cctcacctcg
     3361 aagtcgatat ccagaccaga taacaaattc cgtcgtctcg gagaattaga ggctaagacg
     3421 atcttgtact tttttaaatt ctctaacata acctattcga ttaagcgtta cacattcacc
     3481 aaaattttac cacccaaaag cctcctcgcc gaaccagtgt ccttgcgccc gcatcgtttg
     3541 ctcgatcacg tccctagcta cgccttcgcc acctcgccgg gaggatatat atttcgctat
     3601 ctccttgatc tccggagccg catccgcagg tgccaccggc aatccgactt gcgtcattac
     3661 ctcataatca ggaatatcat cacccgcata catgatttgc tcaggagaca agcccgtttt
     3721 ttccataaaa tccttaaagt catgcacctt tacagcgcta cgcatataaa tacgttgtat
     3781 tcctaaacga gaaaagcgaa tctgtacggc ttccgtatat ccgcccgtaa ttatagcgac
     3841 ctcataacct ttcttcacgg ccaattgcaa ggcatagcca tccttgatat tgaccgtacg
     3901 catcggatcg ccattcgggt gaagcggaat cacatcgcag gatagcaccc cgtctacatc
     3961 aaagacaaaa gcctttattt ttctcaaatc atagtttata ctactcatgt cgagcctcct
     4021 tatgtatact tcggctaatc agctcatata gatttcgcat atccggatct ttaagcatag
     4081 ccatatgttt gtttatcaca ttttcgtcat atcgtatagc tggtcccgtt tgggcccgcg
     4141 ccggcgacat tacatgtacc ttagcggctg tctcgtctat caaaggtaac aagacctctc
     4201 ccggtatttg ctgttcttcc aagatctttt cagctagcgc atacatatga ttcgtaaaat
     4261 tacaagcgaa aaccgccgct aaatgtaagt tctttcgctt ctcggaggag aggaaacgga
     4321 catcacagga gagcgcccta gccacctctc ccagcacctt ctcatcttca gatgagttcg
     4381 cctctaaaaa gaacggtatt ttcttgaaat ccacctccct actcttacta aacgtttgta
     4441 acggataaac caccccatat ctagccgtaa aaccttcaaa tacagagatt ggcatactcc
     4501 ctgccgtgtg cacccacaaa ccgttattcg gttttacacg ggcgataaca tcttggagca
     4561 cggcatcttt caaagagaaa acatacaagt cggcatcttc cacaatctct tccgggatca
     4621 cggtccaccc acatcccaat tcatcagcta aaatcttagc atgctcactt gtgtgactat
     4681 atacttgccc gatactcatt ccggacttac gcatttccaa cgaaagccgg gtagctaagt
     4741 ttccggcacc aacaaatacg actctcattc tcccgtctct ttattttctt ccggaagaga
     4801 aaactttcct atatgtatct tctcccattg taaatgggat tcatcaaaag gcttacgaac
     4861 ctgatcctta taaccgatac caatgataga caagacatcc aattgataag ggatatccag
     4921 caacgaacga acataattat tcgaatccgc ctcgtcctct gttacccggt tccggatctg
     4981 acaccagcaa ctgcccaatc ccaaatcctc tgcttgcaat tgcatataaa tagaagcgac
     5041 cgaagcgtcc tcgatccaaa catcgctttc catcacattc gccaagacaa ccacggctaa
     5101 ggcacaaccc tccagaaaag tggaaccatt tttcttacac ccggcaagtt tcttcaacat
     5161 ttccttatct tccacgacca cgaactgcca aggattacta cgttttgagg ccggagccat
     5221 caacgccgct ttcaagatca gttctacctg ctcgggtgaa agtagttgtt cggtaaactt
     5281 acgtgtactt cttctatttt gtataagtgt tgcaaaactc tccatttttt tcgttctttg
     5341 tactctttta atattaagat tcgcaaatat aaatataatt ttttgcaccc atatatacgt
     5401 atcgttcttt tttctcgtta gtatttttat aattgaacaa tagattatga agattcgtgc
     5461 gatagccgcg ctgctattta tacttatttc cgtgagtgcc tttggcgaag gccgcataaa
     5521 aatcactggt tatgtccgtg acgccgacgg taaccctctg gaattagtga atgtccgggt
     5581 taagaacacg ttgatcggct ccatgaccaa cgagaaggga tattattcct tttccatatc
     5641 gccgggggat tctatctcca ttatttactc ttgtctggga tataataaag ctgaacgtat
     5701 cattccttca gcacaagccg atatgcgcct gaacgtacag atgaactata cctcatttga
     5761 tttaggggaa gtatctgtta ctgccatccg caagcagacc acgaccatgg agtccctaaa
     5821 tgcggacaaa atcaagttat tgcccgatcc ttccggaggt agtatagaga gcttggtcgt
     5881 tacgtttgcc ggagtatcgt ccaataacga gttaagttcc cagtattccg tacgtggagg
     5941 tagttatgat gaaaatatcg tttatgtgaa tgggatcgag gtattccgtc cacttctgat
     6001 tcgctcggga caacaagagg gccttagctt tatcaatccg gacctaacgg aggcggtcaa
     6061 tttcgccgcc ggtggcttcg aggctcgtta cggagacaag atgagttctg tgctggatat
     6121 tacctataaa aaacctaaga tattcgaagg ctcggcttct gcgagcttgt tgggcgcgaa
     6181 tgcttatgta ggcagttcta tcggtaaatt tacccaagta acgggtttcc gctttaaaag
     6241 cggtcggtct attttgggta ccatggatac agacgcagaa tacgacccta aatttatcga
     6301 tttgcaaact tacatcacgt accaattggc ccctaaatgg gaaatcaatt tcttgggaaa
     6361 cctcgctaac aataattata aattcacccc ttatagccga gaaacctctt tcggtacagc
     6421 cgagcatccc aagaacttca aagtctattt cgacggaagg gaaagagacc gtttccaaac
     6481 cttattcggt gcgcttacat tgaaacacaa ccccaatgag aacacagagt tgggacttca
     6541 agcctccgct ttcaaaagca aggaagaaga gggatacgat atcgccggag aatattggct
     6601 gagcgagaac ggagcggaaa atccgaatga cgacgcgtca gccgccatgt ccgtaggccg
     6661 ttatcacgag cacgcacgaa accgtttgaa ctccaccgtc atgaatgtcg ggcactatgg
     6721 gatggcccgc cttttaaaca atacgttgaa atggggagcc acggtacaaa tggagaaaat
     6781 caatgataag atcagtgaat gggaaaaaag ggattcctca ggttattctt tgccccaaac
     6841 cggtaataac gtaagtgtat attcgaacct cttttctgat aatcagatag aaagcacacg
     6901 cttttccgct tatgcgcaag acgcattcaa attcaggacc aagcaaggtc tgttcacgtt
     6961 agtcgcaggg gttagaggta gttattggac ttataataag gagttccttt tcagtccccg
     7021 tgcctcattg ggctttatcc cgaacttcga ccaagacttg acgctccgtt tcgccaccgg
     7081 actgtattat caatcgccct tctacaagga attacgtaga gtagacaaag ataagaacgg
     7141 caataatatc acggtattga acaaagatct aaagtcacaa cgctccatcc atttcatatt
     7201 gggaggagat tatacgttcc gtgccgtaga ccggaatttc aaggtgaccg ccgagatgta
     7261 ctataaaaag ctggacaatc tgaatcccta caccgtagat aacgtcaaga tccgctatta
     7321 cggtgagaac tgcgccaaag gttacgccat gggactcgat gtcaaattct tcggagaatt
     7381 cgtaccgggt accgactcat ggatcagctt ctccttgatg aaagcccagc aaaccatccg
     7441 ggaaacaacg accgttccta tggccaatag ccaaggctac aacatctcac tcttcttcca
     7501 agattatttc ccgggctata aacgagtcaa gctaaatctg aaaggagttc tatccggagg
     7561 acttccccag acaatcccgg gcaaaggata cgaagccggc tatttccgta cgcccgccta
     7621 caaacgtgta gatatcggcc tctcctatca attggcagga ggcacggacg ctatcatgga
     7681 caggggcttc ttccgccatt tgaaaaacat ttggctaggt ctggatgtgt ttaacatatt
     7741 agacatcaaa aacgttagtt cctactattg gataacagat gtatataatg tccaatacgc
     7801 agttccaaac tatctgaccg gacgtcaatt gaacgttcgt ctgattgtcg atttttaata
     7861 aaatgtatct ttaaacacat ttactgggag ataaaaacaa aaaattattt cctcattcat
     7921 aaaaagtagt gtacatttgc acacaataga aacaaacatt tactaaatct ttaaattatt
     7981 attgacatgg aacttacaca tatcgaacat ttaggtatcg cagtgaagag tatcgaggct
     8041 tgtttaccct attatgaagg cgttcttgga ttaaaatgct acaatatcga agtagtagca
     8101 gaccaaaaag taaaaaccgc atttttcaag gtaggacaga ctaagattga actactagag
     8161 ccgaccagcg aagatagcac gatcgcgaaa tttatcgaga aaaaaggtga aggtatccac
     8221 catatcgcat tcgcggtacc tgatgtacag gcagctttga acgaggctga ggaaaaaggc
     8281 gttaaattaa tcgataaagc tcctcgtggt ggcgcggaag gcttgaacat cgctttcctt
     8341 cacccgaaat caacttgcag cgtattgaca gaactttgca tgccgggcaa caaataatta
     8401 atccgttcat ttctaacaac aaatcaaaat acaatgagta accagcttga aaaagtaaaa
     8461 gagctcatcg cacttcgtga gcaagctcgc ttgggtggag gagagaaaag aatcgaatca
     8521 cagcacaaaa aaggcaaata taccgctcgt gagcgtatcg ccatgttgct tgacgaaggt
     8581 agtttcgagg aattcgacat gtttgttcaa caccgttgta caaacttcgg tatcgagaaa
     8641 actaaatatt taggcgatgg tatcgtaaca ggttatggta cgatcgacgg acgtttggta
     8701 tatatcttcg ctcaagattt caccgtattc ggtggagcct tgtctgaggc tttggctatg
     8761 aagatctgta aagtaatgga tcaagccatg aagatgggcg ctcccgttat cggtttgaac
     8821 gactccggcg gagctcgtat ccaagaaggt gtaaacgcct tggcaggata tgcggagatt
     8881 ttccaacgta acatcttggc atctggtgtt gttccccaga tttccggtat cttcggccct
     8941 tgcgccggtg gagccgttta ttctccggct ttgacagact tcaacatcat gacacgtggt
     9001 accagctaca tgttcttgac aggtccgaaa gtagtaaaaa ccgtaacagg tgaggatgta
     9061 acccaagagc agttgggtgg agccagcgta cacactacaa aatcaggtgt agcccatttc
     9121 gctgttgata cagaagagga tggtttgcaa ttgattcgta aattgctcag tttcttacct
     9181 cagaacaact tagaggaaac gccgttagtt gagtgtaaag acccgatcga tcgtctggat
     9241 gatgtattga acgatatcat tcccgataac gctaaccaat cttacgatat gtatgaggtt
     9301 atcggtacga tcgtcgataa caacgagttc ctagaggtcc atgcggacta cgctaagaat
     9361 atcatcgtag gtttcgctcg tttcaacgga caatctgtcg gtatcgtagc caaccagccg
     9421 aaggttatgg caggatgctt ggatagcaa
//
LOCUS       DBMDTB010000129         9446 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_2042_length_9446_cov_13.366827, whole genome shotgun sequence.
ACCESSION   DBMDTB010000129 DBMDTB010000000
VERSION     DBMDTB010000129.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 9446)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 9446)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9446
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2042_length_9446_cov_13.366827"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            302..712
                     /locus_tag="ACZPB4_15155"
     CDS             302..712
                     /locus_tag="ACZPB4_15155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HIR1099592.1"
                     /translation="MNKKLQIHNSTAEFFIFQIENKEEGIEVLYQDESLWLTQDAIAV
                     LFDKSRSTITEHLQNIFQSQELQEDSVCRKFRRTASDGKSYATKYYKFAIRGYVVDKK
                     RFEKYRIIQDRLFQSDFDKYQTDNLLDFDNEIES"
     gene            750..2297
                     /locus_tag="ACZPB4_15160"
     CDS             750..2297
                     /locus_tag="ACZPB4_15160"
                     /EC_number="3.1.6.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase family protein"
                     /protein_id="HIR1099593.1"
                     /translation="MKSTLIVGIGASLLTAGIAKAQQRQDITPRTPNVLFIYADDLGY
                     GDLECYDGTQVKTPNINRLAKNGIRFTNAHATASTSTPSRYSMLTGEYAWRRPGTDIA
                     AGNAGMIIRPERYTIADMFKNAGYATAAIGKWHLGLGDKAGEQDWNAPLPTALGDLGF
                     DYSYIMAATADRVPCVFIENGQVANYDPDAPIYVSYQKNFPGEPTGKDNPELLYNQKP
                     SFGHDQSIVNGISRIGYMKGGGKALWKDENIADSIVTHAIDFIKENKEKPFFMYFATN
                     DVHVPRFPHDRFRGKNPMGVRGDAIEQFDWSVGQLMKTLDEMGLTENTLIILSSDNGP
                     VVDDGYADRAVELLGDHKPAGPLRGNKYSAFEGGTRIPAIVHWPKEIKQAAVSDALVS
                     QIDWFASLASLTNSRLPKGSAPDSYDYLDTWIGKSKEDRPWVIEQALNKALSVRTKDW
                     KYIEPSVGSAIMEYEKIETGYSPEPQLYDMTKVYEEGNKALQHPEIVFQLQGILKGVR
                     DHTIKAK"
     gene            2297..3859
                     /locus_tag="ACZPB4_15165"
     CDS             2297..3859
                     /locus_tag="ACZPB4_15165"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HIR1099594.1"
                     /translation="MERRNFIKSSLGIGLGATLPGMTHSKSGKEAETAVSPAMPVKSG
                     KPHIILIMTDQQRGDALGCMGNKAVISPNIDRLAQEGSLFVSGYSSAPSSTPGRAGLL
                     TGMSPWHHGMLGYGRMALKYRYEMPQMMRNLGYYTFGIGKMHWFPQKALHGFHATLID
                     ESGRVESPDFISDYREWFQLQAPGKDPDLTGIGWNDHAAGVYKLDERLHPTAWTGQTA
                     CELIRNYDNDKPLFLKVSFARPHSPYDPPLRYLDMYKDTDIPKPHIGDWCGQYAEPKD
                     PLQGASDAPFGNFGDAYAINSRRHYYANITFIDDQVGQIIQTLKDKGMYDNALICFTA
                     DHGDMLGDHYHWRKTYPYEGSAHIPYIVKWPAGISKSIPDGSSIEQPVELRDFLPTFI
                     DIAGGSVPPDMDGRSLLKLIQGQQEQWRPYIDMEHATCYSDDNYWAALTDGKIKYIWN
                     FHNGSEQLFDLREDPGETHNLSEDAAYQNKLSELRKMMVEHLSERGDSFVKDGKLMTL
                     DTTLLYSPNFPK"
     gene            3963..4622
                     /locus_tag="ACZPB4_15170"
     CDS             3963..4622
                     /locus_tag="ACZPB4_15170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysE family translocator"
                     /protein_id="HIR1099595.1"
                     /translation="MLGIVSKGIIIGILVSAPMGPIGMLCIQRTLNKGRWHGFVTGLG
                     AALSDVIYAALTCLGMGVVVNFVEANQAPLQLIGSIVLGIFGYYIFQSNPTRNLKKHR
                     EKKLSFTQDFITAFLLTFSNVLIVLLYIGLFARFGFVLPEHSFWLLVLGIVCIGLGAV
                     LWWFGITYIIGKLRKWFNVRGIWLLNRIVGSVIIVLSIIGALSVLLTSYLQWPLLQIY
                     S"
     gene            4624..5265
                     /locus_tag="ACZPB4_15175"
     CDS             4624..5265
                     /locus_tag="ACZPB4_15175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0016052 - carbohydrate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate-binding family 9-like protein"
                     /protein_id="HIR1099596.1"
                     /translation="MKRLKVPVIPVLDVLDITSIEPILEVQSQREFLTHANWHEYPYK
                     PITAFNIARTEKNLYIRYSVQGNSLKASYEMDNSSVHKDSCVEFFMKKEGDSHYMNFE
                     FNCIGTCDAARRTSRDIKTSLSQEEYKSIIRLPSVRRRAFEEIKGIHTWNLIVVIPLK
                     LMGLDPSNLPEKILGNFYKCADETMNPHFVSWSPIDLPEPNFHCPEFFGEIYL"
     gene            complement(5321..5728)
                     /locus_tag="ACZPB4_15180"
     CDS             complement(5321..5728)
                     /locus_tag="ACZPB4_15180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6249 domain-containing protein"
                     /protein_id="HIR1099597.1"
                     /translation="MMDFISVPLVVGIVCAGIYGLFELFVRKRERLAIIEKIGDKLDA
                     SAFDGKLGLPNYMRNFSFSSLKAGCLLAGIGLGLLVGFIINMCMATNSYYDDGWYRHE
                     VAGTAYGASVLLFGGIGLIIAFVIELKLGKNNK"
     gene            5878..6435
                     /locus_tag="ACZPB4_15185"
     CDS             5878..6435
                     /locus_tag="ACZPB4_15185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HIR1099598.1"
                     /translation="MELYTDTYYIQRIQAGDVACFACLLDKYSRPINSLILKVVRSQE
                     EAEELAQDTFMKVFKNLASFKGDCSFSTWIYRIAYNTAISSVRKKRYEFLAIEETTLE
                     NVSEEEITNLFGQTESTEQVQRLEVALEQLLPDERALILLFYWKEKTIEELVSITGLT
                     ASNIKVKLHRIRKKLFVLLNGMDHE"
     gene            6428..6784
                     /locus_tag="ACZPB4_15190"
     CDS             6428..6784
                     /locus_tag="ACZPB4_15190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099599.1"
                     /translation="MSKINTNKEQPDLLGDLFKRIPEEELPASFRSNVMRQIMLESAK
                     AKKRDERFSLLAAIVASLIMISLAIVSFVYMEIPKIAIPTISTSALAFYLYIGAITLI
                     LLLADYKLRNLFHKKG"
     gene            complement(6729..8873)
                     /locus_tag="ACZPB4_15195"
     CDS             complement(6729..8873)
                     /locus_tag="ACZPB4_15195"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1099600.1"
                     /translation="MRLKNRLNNWISIRMGMVIVIFLGVSCGSMRSSTPPPAKDRLTE
                     IDSLERLLPDCPTIASTLPLLRRLAFLYQQQSEMKVYNERLYENAMAVDSISVAYLGL
                     KNLAEYYYDQSVRDSLEYYCSLVDSIAKARHEYPNVLFDVKSLSSQDLLWLGNYELAM
                     SEAMDLYRLASNLDHRYGLLRCSETLGLIYQRIRRDSDAVVSFQESLDLLKDIKDVPD
                     IMDTKVRLTSYQLESSVRTKQYASTERILGQYKALLDEQYKIYQEKNDLLSIKREYWL
                     LYSFYTSFYLSQGDLENAKRSLDQASSYADSNWVEGDYAINTYLTVKARYHKAAGDIP
                     LALHCINEVLETERLPEDIQFKADILKEQGQLGEVMALYDELYSTLTKRRGTSFLRQV
                     NQLRTLHELHEKELKETELKEAGQRIARKQDLLIFILSISVVLLILLYVLFLYYRHLR
                     SLKNQLQREKELLLESQRQLIKEKTRAEEASLMKSAFLANMSHEVRTPLNAIVGFSGL
                     LVEPSTDEEERKEYSSIIRNNTDLMLNLVNDVLDLSRMETGDLHFDIKDHLLLVCCQM
                     ALESVRHRIPDGVKLTFSPAGEPIVVHVDNLRLQQLLTNLLTNAAKFTEKGEINLSFQ
                     LEPDRKKVCIAVTDTGAGIPLEKQATIFNRFEKLDDYKPGVGLGLSICLLIAERLDGA
                     LFIDSSYTDGARFVLILSCEIDSSIYNPPIEV"
     gene            complement(8870..>9446)
                     /locus_tag="ACZPB4_15200"
     CDS             complement(8870..>9446)
                     /locus_tag="ACZPB4_15200"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1099601.1"
                     /translation="EKIRFAGEVNHSSELLLNLVNDVLDLSRLESGKIKFSVKPNDLV
                     ACCQRALDSIRHRVKPGVRLTFTPSIESYTLNTDALRLQQLLTNLLSNAAKFTSEGEI
                     NLSFTVDEGKEEVRFSVTDTGCGIPEDKCEKIFERFEKLDDFIQGTGLGLSVCQIISE
                     QLNGSLSVDISYKDGARFVFIHPTNLIETPI"
BASE COUNT         2676 a         2305 c         2127 g         2338 t
ORIGIN      
        1 ggcacaaata tataaattgt ttaatatcaa caccttaaaa acacgattgt gatttttgaa
       61 aaacacgtac gtgtttctgt aaaaagtcgt acatgttttt cgggaaacac gtacgacttt
      121 ttacagcatc attcgataag gagcaagagc gtacatgaaa atatacgata agcccccctt
      181 ttaaccagag ccaaaaagca tttcttccta agctccatct catagatatt ttggtgtagt
      241 taccctgatt ctgaaataat ttggttattt ttgtatataa ttaatgtcca tagaacatgc
      301 catgaataag aaattgcaga tacacaacag cacggctgaa ttctttattt tccaaataga
      361 aaataaagaa gaaggtatag aagtcttata tcaagacgaa agcctttggc tgacgcagga
      421 tgctattgcc gtattgttcg ataaaagccg ttccactatc acggaacatc tacaaaatat
      481 atttcaaagc caagaattac aagaagactc agtctgtcgg aaattccgac gaactgcttc
      541 cgatggcaaa agctacgcaa ctaaatatta caagtttgcc attcgcggct atgtcgttga
      601 taagaaaaga tttgagaaat accgtatcat tcaagaccgt ctattccaat ccgattttga
      661 taaataccag acagataacc ttcttgattt tgataacgaa atagagtcat aatacaaact
      721 ctttatagaa catctaaata ataaacaaca tgaaatcaac acttatcgta gggatcggtg
      781 cctcgcttct tacagccggt atcgcaaaag cccaacagag acaagacatt acacctagaa
      841 cgccaaacgt attgttcatc tatgcggatg acttgggata tggagacttg gaatgctacg
      901 acggcacgca agtgaaaacc ccgaatatca accggctcgc caagaacggt atccgcttca
      961 ccaacgctca cgcaaccgcc tctaccagta cgccctcccg atattccatg ctaaccggag
     1021 agtacgcatg gcgccgcccg ggaacggaca tcgccgcagg aaacgccgga atgatcatac
     1081 gaccggagcg ttatacgata gccgatatgt tcaagaacgc gggatacgcc acggccgcta
     1141 tcggcaaatg gcatcttggc ctaggagaca aagcgggcga gcaagactgg aacgccccac
     1201 tccccaccgc ccttggcgat ctgggatttg attattccta tatcatggcg gcgacggcag
     1261 accgcgtccc ctgcgtattc atcgagaacg ggcaggtggc gaactacgat ccggatgccc
     1321 cgatctatgt cagttaccag aagaactttc ccggagagcc gaccggaaaa gataatccgg
     1381 aattattata caaccagaag cctagtttcg ggcacgacca atccatcgta aacggaatca
     1441 gccgtatcgg ttacatgaaa ggtggcggca aggcgctttg gaaagacgag aatatcgccg
     1501 attctatcgt gacacacgcc atcgatttta tcaaggagaa taaagagaag cctttcttca
     1561 tgtatttcgc cacgaacgac gtgcatgtac cccgcttccc gcacgaccgt ttccggggaa
     1621 agaacccgat gggcgtgagg ggcgacgcta tcgagcaatt cgactggagc gtaggccaat
     1681 tgatgaaaac attggatgag atgggattga cggaaaacac cttgatcatc ttgtcaagcg
     1741 acaacggacc tgtcgtagac gatggttacg cggaccgggc cgtggagcta ttaggcgatc
     1801 ataaacccgc cggcccgctt agaggtaata aatacagtgc cttcgaaggg ggaacccgta
     1861 tcccggctat cgtacattgg ccaaaggaga tcaagcaagc cgccgtatca gatgcgctag
     1921 tgagccagat cgactggttc gcctcccttg cctcactgac gaattcccgt cttccgaaag
     1981 gaagcgcgcc ggatagttat gattatctgg atacttggat cgggaaaagc aaggaagacc
     2041 gcccgtgggt aatcgagcaa gcgcttaata aggcactctc cgtccgtacg aaagattgga
     2101 aatatatcga gccgagcgta ggttccgcta tcatggaata tgagaagatt gagaccggat
     2161 attcccccga gcctcagtta tacgacatga cgaaggtcta cgaggaagga aacaaggcct
     2221 tgcaacatcc ggagatcgtt ttccaattgc agggaatttt aaaaggagtt cgggatcaca
     2281 caatcaaggc taaataatgg aaaggagaaa cttcattaag tcatccctcg gaatcgggct
     2341 gggcgcgaca cttccgggga tgacgcatag caaaagcggg aaagaggcag agaccgccgt
     2401 ctctcccgcc atgcccgtaa agagcggtaa gccgcatatc atcctgatca tgaccgatca
     2461 acaacgtggc gacgccctcg gctgcatggg aaacaaggcg gtgatctcac cgaatatcga
     2521 ccggctggcg caagaaggct cgttgttcgt gagcggatat tcctccgctc caagtagcac
     2581 tccgggacgg gccggtttat tgaccgggat gtctccttgg catcatggta tgctgggata
     2641 cggacgcatg gccttgaagt atcgttacga gatgcctcag atgatgcgga atctggggta
     2701 ttataccttc gggatcggta agatgcattg gtttccgcag aaagcacttc acggattcca
     2761 cgcgaccttg atcgacgaga gtggccgggt ggaaagtccc gatttcatca gcgattaccg
     2821 ggaatggttt caattgcagg cacccggcaa agacccggat cttacgggta tcggctggaa
     2881 cgaccatgcc gccggtgtct ataagttaga cgaacggctt catcctacgg cttggaccgg
     2941 acagaccgct tgcgagttga tccggaacta cgacaacgac aagcccttat tcctcaaggt
     3001 atcattcgcc cgcccgcata gtccttatga tccgcctcta cgttatctgg atatgtataa
     3061 ggacacggat atcccgaaac cccatatagg agattggtgc ggacaatacg ccgagccaaa
     3121 agatcctctc caaggagcat cggatgcccc attcggtaat ttcggggatg cgtatgccat
     3181 aaactcccgt cgccattatt acgccaatat cacctttatc gacgatcaag tagggcaaat
     3241 catccagacc ctaaaagaca aaggtatgta cgacaatgcc ctgatttgtt tcacggcgga
     3301 tcatggcgat atgttgggcg atcattatca ttggcggaaa acctatccat acgagggttc
     3361 ggcccatatt ccttatatcg taaaatggcc cgccggtata tccaaatcca taccggacgg
     3421 aagcagcata gaacaacctg tagaactgag agacttcttg cctaccttta tcgatatcgc
     3481 cggcgggtcg gttcctcccg atatggacgg gcggtcttta ctcaagctga tccaaggcca
     3541 gcaggaacaa tggcgcccct atatagacat ggagcatgcc acttgctata gcgacgataa
     3601 ttactgggca gcccttaccg atggaaagat taagtatatc tggaatttcc acaacggaag
     3661 cgagcagttg ttcgatttac gggaagaccc gggagagaca cataacctta gtgaggacgc
     3721 agcctatcag aataagttgt ccgaattacg caagatgatg gtagagcatc tgtccgagcg
     3781 aggagattca ttcgtgaaag acggtaaatt gatgactctc gatacgaccc tattgtacag
     3841 tcccaatttc ccgaaataag ggacgagcga gcctcgtccc tacagtatct tacgtttttt
     3901 accttttttt tatcgcggaa tggatgtatc tttgcccgag aaactagaag agactcaact
     3961 taatgctagg aatcgttagt aaaggaatca ttataggtat attggtttcg gcccccatgg
     4021 gccccatcgg tatgctctgt atacaaagaa cactaaataa aggacgttgg cacgggttcg
     4081 tcaccggatt aggggccgct ctatccgacg tgatttatgc ggcactgact tgtctgggca
     4141 tgggagttgt ggtcaacttc gtggaggcga accaagcgcc cctgcaattg atcggaagta
     4201 tcgttctcgg cattttcggg tattatatct tccaaagcaa cccgactagg aacctaaaga
     4261 aacaccgaga aaaaaaatta tcgttcaccc aagactttat tacagctttt ctacttacct
     4321 ttagcaacgt gttaatcgtc ttgctctata taggattatt cgcccggttt ggtttcgtgc
     4381 tgcctgaaca ttcgttttgg ctgctggtat tgggcattgt ttgcataggg ttaggggccg
     4441 ttctttggtg gttcggcata acatatatta ttggaaaact gagaaaatgg ttcaacgtta
     4501 gaggtatttg gttactgaac cggatcgtgg gctctgtcat tatcgtattg tctattatcg
     4561 gtgccctatc ggttttattg acctcctact tacaatggcc tttacttcaa atctatagtt
     4621 aaaatgaaaa gactgaaagt tcctgttatc cccgttctgg atgtactcga tataacatcc
     4681 atagaaccga ttcttgaggt gcaatcccaa cgtgagttcc tcacccatgc caattggcat
     4741 gagtatccat ataagccgat caccgctttt aatatagccc ggacagagaa aaatctatat
     4801 atacgatata gcgtgcaggg taattcgcta aaggcgtctt atgagatgga caattcctcg
     4861 gtccataagg atagttgcgt ggaattcttc atgaaaaagg aaggtgactc gcattatatg
     4921 aatttcgagt ttaattgtat cgggacttgc gatgccgccc gccgtacctc acgggatatc
     4981 aagacgtcgc tttcgcaaga agagtataaa agcatcataa gactcccatc cgtgagaaga
     5041 agggcattcg aggagattaa aggtattcat acatggaact tgatcgtagt cataccactc
     5101 aagttgatgg ggttagatcc tagtaatctg ccggagaaaa tactagggaa cttctataaa
     5161 tgcgccgatg aaacaatgaa tccgcatttc gttagttgga gtccgatcga ccttcccgag
     5221 cctaatttcc attgtcctga attcttcggg gagatctacc tgtagtatag acgtagcgtg
     5281 ctgcatgcag cacgctacgt ctatacaggc aagcctatgg ctatttatta ttcttaccta
     5341 gtttcagctc aatgacgaac gctattatca agccgattcc cccgaacaaa agaaccgaag
     5401 ccccataagc cgtacccgct acctcatgcc tgtaccaacc atcatcataa taagaatttg
     5461 tcgccataca catattaata ataaagccta ccaacaaacc taatccgatt cccgccaaaa
     5521 ggcacccggc ctttaagcta ctgaacgaga agtttcgcat gtagttaggc agtcccaatt
     5581 taccatcgaa agcagaggca tccagtttat caccgatctt ctcgataatc gccaaacgtt
     5641 ccctcttgcg aacaaacaac tcaaataatc cgtaaatacc tgcacaaacg attccgacaa
     5701 ctagcggaac agaaataaaa tccatcataa ctgtataatt ttaattgatt cattcatatt
     5761 gtttgctaat ttgacgcaac agtttcccat aggttacacc tccgggctga aaaatatttt
     5821 ttatttttgt taccgcaagt tgtaacctat ttacccggct tgcgtccatt aagtacaatg
     5881 gaattgtata ccgatacata ttacatacaa aggatacaag cgggggacgt ggcatgtttc
     5941 gcttgccttt tggacaagta tagccgtccg attaactcgt tgatcctcaa agtggtacga
     6001 agccaagagg aggctgagga gttggcgcaa gatacgttta tgaaggtatt caaaaacctc
     6061 gcctcattca aaggggattg cagtttctcc acatggattt accggatcgc ttacaacacg
     6121 gcgatctcgt cggtccggaa gaagagatat gagtttctag cgattgagga gactacactt
     6181 gaaaacgtat cggaggagga aattacgaac ctgttcggac aaaccgaatc cacggaacag
     6241 gttcaaagat tggaagtcgc ccttgaacaa cttctaccgg acgaacgggc cttgatcttg
     6301 ctcttttatt ggaaagaaaa aacaatagaa gaactggtct ctatcaccgg cttgaccgcc
     6361 tcgaatatta aagtcaagct acatcgcatc cgaaaaaaat tgtttgtatt attaaatgga
     6421 atggatcatg agtaagataa acacaaataa ggaacaaccc gatttattgg gggatttatt
     6481 caaacgcata ccggaggagg agcttcccgc ctcgttccgt tcgaacgtaa tgcgacaaat
     6541 catgcttgag tccgcaaagg cgaagaaacg tgacgaacgg ttcagcctgt tagcggcgat
     6601 cgtggcctcg cttatcatga tttccctcgc gatcgtatct ttcgtatata tggagatacc
     6661 caagatagcc atccccacga taagcacatc ggccttggct ttctatttat acataggggc
     6721 catcacgctc atacttctat tggcggatta taaattgagg aatctatttc acaagaaagg
     6781 ataagcacga agcgagcccc gtctgtatac gaagagtcga taaacaaggc gccgtccagc
     6841 cgctcggcga tcaggagaca gatagagagc cccaaaccca cgccgggctt gtaatcgtcc
     6901 agcttctcaa agcggttgaa tatggtagcc tgtttttcaa gggggattcc ggcgcccgta
     6961 tccgtaacgg ctatacatac cttcttccgg tccggctcaa gttgaaacga tagattaatc
     7021 tcgcctttct ccgtaaattt agcggcgttt gtcaacaggt ttgtcaacag ttgttgcagg
     7081 cgcagattat ctacatgtac cacgattggt tccccggcgg gagaaaaagt caatttaacc
     7141 ccatccggta tccgatggcg tacactctcc aaagccattt ggcaacatac taaaagcaga
     7201 tgatccttga tgtcaaaatg aaggtctccg gtctccatcc gggataagtc caatacgtcg
     7261 tttaccagat tcaacatcag atccgtgttg ttccggatga tagacgaata ttccttccgc
     7321 tcctcctcat cggtagaagg ttccaccaat aaaccggaga accccacgat agcatttaac
     7381 ggagtccgga cctcgtggct catattcgca aggaaagcgc ttttcatcaa gctagcctct
     7441 tccgcacggg tcttttcctt tatcaactgt ctttgagatt ccaaaagcaa ctctttctcc
     7501 cgctgcaact ggttcttcaa ggatcgtaga tgacggtagt acaaaaacag gacatagaga
     7561 aggatcaaca gcacgaccga tatggatagg ataaagatca gcagatcctg tttccgggcg
     7621 atgcgttgcc cggcctcctt caattccgtt tctttcaact ccttttcatg cagctcatgc
     7681 aaggtacgca attggtttac ctgccggaga aaagaagttc cccgcctttt cgtcagcgta
     7741 ctataaagtt cgtcatatag agccatgacc tccccaagtt gtccctgttc cttcaagata
     7801 tccgccttga actggatatc ctcgggcagc cgctcggtct ccagcacttc atttatacaa
     7861 tgaagcgcca gcggaatgtc tcctgccgcc ttatgataac gggccttaac cgtcaggtag
     7921 gtattgatcg cataatctcc ctcaacccaa ttactatccg cataagaaga ggcttgatcc
     7981 aacgaacgct tggcattctc caagtctcct tgcgaaagat aaaaactcgt gtaaaaagaa
     8041 taaagtaacc aatattctct tttaatagac aaaagatcgt ttttctcttg gtagatctta
     8101 tactgctcat cgagcaaagc cttatattgc cctaagatcc gttccgtcga cgcatattgc
     8161 ttcgtccgta cgctactctc caattgataa gaagttaacc ggaccttagt atccatgata
     8221 tccggcacat cctttatatc cttcaataaa tcaaggcttt cctgaaaaga gacaacagcg
     8281 tcgctatccc tccggattcg ttggtaaatc aatcctaatg tctccgagca acggagcaag
     8341 ccatatctat gatccaagtt gctcgccaac cgatacagat ccatagcttc gctcatcgcc
     8401 agctcataat tcccaagcca aaggagatct tggctggaaa ggctcttcac gtcaaacaac
     8461 acattcgggt attcatgccg ggccttggct atggagtcta cgagagaaca ataatattcc
     8521 aaactatcac gtacagactg atcgtaataa tattcggcta agttcttcaa tcccaagtat
     8581 gcgacagata tagaatccac cgccatcgca ttttcataaa gacgttcatt ataaaccttc
     8641 atctcggatt gctgctggta caggaatgcc aaccgccgca ataagggcaa ggtagacgct
     8701 attgtcgggc agtccggcaa taacctctcc aagctgtcga tctccgttaa acgatccttg
     8761 gcgggaggag gtgtggaaga tctcatcgaa ccgcaagata cgcctaggaa gatcacgatg
     8821 accatcccca tacgtatgga tatccagtta ttgagtcgat tcttcagtct catatggggg
     8881 tctcaattaa attcgttgga tgtataaaga caaaccgggc tccatcctta taagagatgt
     8941 ccaccgataa agagccatta agctgctccg agatgatctg gcaaacagat agtcctaggc
     9001 cggtaccttg aataaagtcg tccagtttct caaaacgctc gaatatcttt tcgcacttat
     9061 cctccgggat cccgcagccc gtatccgtaa cggagaaacg gacctcctcc ttgccctcat
     9121 ccacggtaaa cgagagattg atctctccct cggaggtgaa tttagcggca ttcgacaaca
     9181 agttagtcag caactgctgt aaacgcaagg catccgtatt caaggtataa gattcaatcg
     9241 agggagtaaa cgtcaatcgg accccgggct tcacccgatg gcgaatcgaa tccaacgccc
     9301 tctggcaaca ggcgaccaga tcgtttggct tcacgctgaa cttgatcttg ccggattcca
     9361 aacgggataa atccaggaca tcgttcacca gattcaatag caactcggaa ctatggttca
     9421 cctccccggc aaaccggatc ttctcc
//
LOCUS       DBMDTB010000130         9000 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_2141_length_9000_cov_11.676705, whole genome shotgun sequence.
ACCESSION   DBMDTB010000130 DBMDTB010000000
VERSION     DBMDTB010000130.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 9000)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 9000)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9000
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2141_length_9000_cov_11.676705"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..700)
                     /gene="lpxK"
                     /locus_tag="ACZPB4_15205"
     CDS             complement(<1..700)
                     /gene="lpxK"
                     /locus_tag="ACZPB4_15205"
                     /EC_number="2.7.1.130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009029 - lipid-A 4'-kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetraacyldisaccharide 4'-kinase"
                     /protein_id="HIR1099602.1"
                     /translation="MLTDHTIKFNKLLTPFSFLYGIGVRFRNQLFDWKILRTERYDLP
                     IICVGNLTVGGTGKTPHTEYIIRLIKDRYRVAVLSRGYKRKTSGFLLADQRSTSKDIG
                     DEPYQMKRKFPDILVAVDADRRRGIRNLLALPENKRPEVIVLDDAFQHRYVAPTLNIL
                     LTDCHRLYTQDKLLPAGRLREPVDGARRADVIIVTKCESYIQPIDFRIIEEDIHLSAY
                     QELYFSRILYGELEP"
     gene            complement(711..2459)
                     /gene="sppA"
                     /locus_tag="ACZPB4_15210"
     CDS             complement(711..2459)
                     /gene="sppA"
                     /locus_tag="ACZPB4_15210"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HIR1099603.1"
                     /translation="MMFASTLGVMLAMGIIITVLISMTIGYIATVGSTPDYTPKSNTV
                     FKIKLDGTLADNPTENPFSALMGDKENMLSLKDLLETIRIAKQNDKIAGIYIESGLLS
                     SGSASLEAIRRSLIDFKESGKFVVAYADNFTQGNYFLCSVADKVFLNPQGILELTGLA
                     SQTLFYKGLMDKVGIEMQIFKVGTYKGAVEPFMLDKLSEANREQIQSYISTIWDNIAE
                     GIAESRGISVNDINHYANEGLFFADPVKTVECGFIDELKYKPEVEAYVKELAGQNGEK
                     LRSANLAQMKTLKASPTKNAPEIAVLYAEGEIKAQTPGNFYDIEQSITEKMADELIKL
                     KNNDDVKAVVFRVNSPGGSAYISEQIWRQVVELKKVKPVVVSMGNVAASGGYYISCAA
                     NKIIAEPNTLTGSIGIFGMFPNASGLFGKLALTTDIVKTNTFSDLGDLSRPMTESEKA
                     LIQGYVERGYQTFLSRCAEGRGMTTEAVNAIGQGRVWTGEQAKERGLVDELGGIELAI
                     STAAGLADLDQYSVTTVSGSKNFLDEFLESQLGEVKLSIVKNVLGNEFEYFKTLNNIK
                     ANCGIQARMPYDMKPL"
     gene            complement(2490..3440)
                     /locus_tag="ACZPB4_15215"
     CDS             complement(2490..3440)
                     /locus_tag="ACZPB4_15215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012056236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4922 domain-containing protein"
                     /protein_id="HIR1099604.1"
                     /translation="MKPNNWVSSSQATELLSKQLVTWPLAEKNYKALEAVQVKSFDMG
                     GFSIRAQFNPARIVSTGAKVDARSLKERKCFLCPENLPVEQERLPFGFRHLVLCNPYP
                     IFPLHFTIPTRKHTPQLILPQWNDFLELTRRLAPFTVFYNGPRSGASAPDHAHFQAVT
                     RGIMPLDEEVTQFIRQSYASVYDNRIYPLTGNLRPGLVIQAATEEAATRLFKKIYAAL
                     PILPGEPEPMMNIFGSYYDNNWVITVIPRKRHRPWQYEAEGNDHLLSSPGTADIGGLF
                     ITPLEKDFKKINPELLRDVYQQVCLSDRDVEEIFVHLSSN"
     gene            complement(3437..4897)
                     /locus_tag="ACZPB4_15220"
     CDS             complement(3437..4897)
                     /locus_tag="ACZPB4_15220"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HIR1099605.1"
                     /translation="MKRINCFIPYGKIEATRQTVAQLAESSLVSQIYLITDDPHAKAI
                     YPCNLIRTENIWSTKTLREIAGYASAHYTLIYTKTEELQLGMYALERFVAIADDTRSG
                     MVYSDYYEKKEGKLNPHPVIDYQKGSLRDDFNFGSLLLYRSSTLQNAIASMDTEYTFA
                     GLYDLRLKVSQNAPLTHINEYLYTEVENDLRKSGEKMFDYVDPKNRSVQIEMEAACTD
                     HLKMIGGYLPPHFKPVRFDEQTFQTEASVIIPVRNRVRTIEDAIRSVLRQEASFPFNL
                     IIIDNHSTDGTSERIQTIAATDPRIIHIQPERDDLGIGGCWNIGIHHSACGKFAIQLD
                     SDDVYSDEHTLRKIVEAFYEQRCAMVVGTYRMTDFDMRTIPPGIIDHKEWTPENGRNN
                     ALRINGLGAPRAFYTPLLRKLNLPNTSYGEDYALGLRISREYPIGRIYDVLYLCRRWE
                     DNSDASLDVVKMNNHNIYKDKIRTWELEARLNMERQ"
     gene            complement(4894..7830)
                     /locus_tag="ACZPB4_15225"
     CDS             complement(4894..7830)
                     /locus_tag="ACZPB4_15225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="golvesin C-terminal-like domain-containing
                     protein"
                     /protein_id="HIR1099606.1"
                     /translation="MREKLSYPVRIIISLLSIFLWSFPAEGQDSESLKKQLDQKLNSF
                     ARQYVSSRTIKIDSILIQKKKVTLFANEALEDIPFREYNVSELYASIAPLFPNASKIV
                     ILTRDTDIESLIPEYDRKGRPNKKRLYSIKESKYPLTRSLSTPHEIKNGLQNRHIALW
                     QSHGLYYAQTAHRWEWQRARMFGTVEDLFTQSFVLPYLTPMLENAGATILIPRERDTQ
                     IHEIIIDNDRSTPGSEYKELDGEKAWSDGEKAGFGHIQATYTNGENPFTQGTYRQTVT
                     QRKGKESLIEWIPEIPESGNYAVYASYQSFPNSTEQALYTIHHAGGETTIAVNQTMGG
                     GTWIYLGNFKFTAHEQAHERIVLTNQSNKSGKIITADAIKIGGGMGNIARSPLESPYP
                     IEAETSGYPRFTEAARYWLQWAGIPDSIYSKSAFRNDYQDDIYARPQWVNYLKEQTHI
                     PIDMAFAFHSDAGTTPDDSIIGTLGIYMSKSNDGIYTNRKSREIARDLTDMIQTQILS
                     DVRKVYNPQWSRRGMWNQSYIEARIPDVPTMLLELLSHQNFADMRYGLDPRFRFLICR
                     AIYKGMLRYICFQNKQEPIVQPLPPDRLYTELVETNKVRIGWKAVQDTLEESASPTAY
                     ILYSRKDSGGFDNGTLVKGEEIILPIETGIIHSYKVAAVNKGGISFPSEIVSVYRSPK
                     GEKDKTVLIVNGFDRISGPASFESTADSLAGFLYAVDRGVPYLNDIAFIGDQFEFRRS
                     ATWNSNDNNGHGDSYNNYAGQVIAGNTFDYPFIHGQAMAGTGYSFVSCSHKSLAEGVV
                     KPDTYPIIDLILGKQRQPVITPVLQDTLRSYLAQGGNLLVSGTNLFSDSWGNAQDRTF
                     VEEVLKGKLASRNASKEGIVNSCASPYGYINGRYTFRTRPNPICYSIESVDGVLPADK
                     LAHTILRYPENNIGAGIVYEGKYRTCSLGFPFEALQTPSERNRLMESILRFFSIQQQN
                     KIQYIQ"
     gene            7950..8060
                     /locus_tag="ACZPB4_15230"
                     /pseudo
     CDS             7950..8060
                     /locus_tag="ACZPB4_15230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007570803.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
BASE COUNT         2133 a         2066 c         2232 g         2569 t
ORIGIN      
        1 cgggttccag ctccccgtaa agaatacggc tgaaatagag ctcttgataa gctgagagat
       61 gtatatcctc ctctatgatc cggaagtcta taggttgtat atatgactca catttcgtga
      121 caatgatcac gtccgcacgt cgagcgccat ccacaggttc ccttaaacgg cctgcgggca
      181 agagcttatc ttgcgtataa agacggtggc aatcggttaa aaggatgttc agcgtggggg
      241 cgacgtatcg atgttgaaag gcatcgtcca gcacgatcac ttccgggcgc ttattctctg
      301 gcagagccaa tagattgcgg atacccctgc ggcgatcagc gtctacggca acgagaatat
      361 ccggaaactt acgtttcatt tggtacggct cgtcaccgat atccttgctg gtacttcgct
      421 gatcggccag caagaaaccg gaggttttcc gtttatagcc acggctgagt acagctaccc
      481 ggtatcggtc ttttatcaaa cgtatgatgt attccgtatg aggagttttt ccggtccccc
      541 cgacagtcag gttccccacg caaataatag gcagatcata ccgctctgtc cgaaggattt
      601 tccagtcgaa cagctgattc ctgaatctca ccccgattcc ataaaggaaa gagaatggag
      661 tgaggagttt attgaactta atcgtatgat ctgtcagcat ggtccagtta ttataacggt
      721 ttcatatcgt aaggcatacg agcttggatt ccgcaattcg ccttgatatt attcaacgtc
      781 ttgaagtact cgaactcatt acccaataca tttttgacga tagagagttt cacctctccg
      841 agctggcttt ccaagaactc gtccaagaaa ttcttggaac cactgacggt agttacgcta
      901 tactgatcca gatcagccaa ccccgccgct gtgcttatag ctaattcaat accgcccagc
      961 tcatcgacca aacctctttc tttcgcttgc tcacccgtcc agacccgtcc ttgtccgata
     1021 gcgttgaccg cttcggtagt catacctcta ccttcggcgc agcgggaaag gaacgtttgg
     1081 tagcctcttt ccacgtatcc ctgtatcagt gctttctcac tctcggtcat gggacgggag
     1141 aggtctccta agtccgagaa tgtgttcgtc tttacgatgt ccgtggtcaa cgctagtttc
     1201 ccgaataatc cggaggcgtt cgggaacatg ccgaagatgc cgatggagcc ggtcaacgta
     1261 ttcggttcgg cgatgatctt attagcggcg catgagatat agtagcctcc cgaggcagct
     1321 acgttgccca tggaaacgac cacaggtttc acctttttca actcgacaac ttgacgccat
     1381 atctgctcgg atatataagc gctacctccc ggggaattca cacggaatac cacggctttc
     1441 acgtcatcat tgttttttag cttgataagc tcatcggcca ttttctccgt gatactttgt
     1501 tcgatatcgt aaaagttgcc gggtgtttgc gccttaatct cgccttcggc gtaaagtacg
     1561 gctatctccg gggcgttttt ggtgggtgag gccttgaggg ttttcatttg agctaagttg
     1621 gccgatctca gtttctctcc attttgtccg gctagctctt tgacgtatgc ttctacctcc
     1681 ggcttatact tcaattcgtc tataaagcca cattctaccg ttttcacagg gtccgcgaag
     1741 aaaagcccct cattggcgta atggttgata tcgttcacgc tgatgccgcg tgattcggcg
     1801 atgccttcgg ctatattatc ccagatggtg gagatatacg attggatttg ctcccggttc
     1861 gcctcgctca gcttatccag cataaaaggc tccacggcac ctttgtaggt acctacctta
     1921 aaaatctgca tctcgatacc taccttatcc atcagtcctt tgtagaatag ggtttgcgag
     1981 gcgagtcccg tcaattcaag gatgccttgc ggattcaaga ataccttatc ggctacggaa
     2041 caaaggaagt aattcccttg cgtgaaatta tcggcgtaag ctaccacgaa cttgccgctt
     2101 tccttgaagt ctatcagcga tcggcggatt gcctccaagc tggcgctacc cgaggagaga
     2161 agccccgatt cgatataaat ccccgcgatc ttgtcattct gtttcgctat ccggatcgtc
     2221 tcgagcaggt ccttcagtga cagcatgttt tccttgtcgc ccatcaaggc ggagaatgga
     2281 ttctccgtcg ggttatccgc tagcgtcccg tctagcttga tcttgaatac cgtattgctt
     2341 ttgggggtgt aatcaggtgt gctacctacg gtggcgatat atcctatagt catggatatc
     2401 aagaccgtta tgattattcc cattgccaac ataacgccta gcgttgaggc aaacatcatt
     2461 ttaaagaatt gtttcatatc tattgaaaac taattagatg acaaatgtac gaaaatttcc
     2521 tctacgtccc ggtcgctgag gcatacttgt tggtaaacat ctcgcagaag ctccgggttg
     2581 atctttttga aatctttttc taaaggggtg atgaaaagac ctccgatatc ggcagttccc
     2641 gggctggaca ggagatggtc gttcccctca gcctcgtatt gccatgggcg gtggcgttta
     2701 cgagggatta ccgtgattac ccaattatta tcgtaatagg agccgaagat attcatcatc
     2761 ggctcgggct caccgggaag tatcggcaaa gcggcgtaga tctttttgaa gagccgggtg
     2821 gcggcttctt cggtggcggc ttggatgacg aggccggggc ggaggttgcc ggtgagtggg
     2881 tatatacggt tgtcgtatac actcgcatac gattgtcgta taaattgggt tacctcttca
     2941 tccagcggca tgatgcctcg tgtcaccgct tggaagtggg catgatccgg tgccgaggct
     3001 ccgctacggg gtccattgta gaagacggtg aagggagcga gtctccttgt cagttccaag
     3061 aagtcattcc attgcggcaa tatcagttgc ggagtatgtt tccgggtagg gatcgtgaaa
     3121 tgcaggggga agatcgggta ggggttgcac aataccagat ggcgaaagcc gaaaggcagt
     3181 cgctcctgtt ccaccggcag gttctcggga cataggaagc atttgcgttc ttttagggat
     3241 cgggcatcta ccttggcccc ggtggaaaca atacgggcgg gattgaattg cgcacgtatc
     3301 gagaaccctc ccatatcgaa ggattttact tgcacggcct ccagcgcctt atagttcttc
     3361 tcggccaatg gccatgtcac gagttgcttg gacagtaatt cggtcgcttg cgatgagctg
     3421 acccagttgt ttggtttcat tgtctttcca tgtttaagcg ggcctcgagt tcccaagtcc
     3481 tgattttatc cttatatata ttatggttgt tcattttcac gacatccaat gaggcgtcgg
     3541 agttatcttc ccaacggcgg caaaggtaca gcacgtcgta gatccgcccg atcgggtact
     3601 cgcggctgat acgtaggccg agggcgtaat cttctccgta actggtgttc gggaggttta
     3661 gtttccgtag caagggtgta taaaaggctc ggggcgctcc aagcccgttg atgcggaggg
     3721 cgttattgcg gccgttctcg ggagtccatt ctttatggtc gataattccg ggcgggatgg
     3781 ttcgcatatc gaaatcggtc attcggtagg ttccgaccac catggcgcat cgctgctcgt
     3841 agaaggcttc cacgatctta cgcagggtat gctcgtcact gtatacatca tcgctatcca
     3901 attggatggc gaacttgccg caagccgaat ggtgtattcc tatattccag caacccccga
     3961 tgccgaggtc gtcacgctcc ggctggatat ggataatacg agggtccgtg gcggcgatcg
     4021 tttggattcg ctcggaggtg ccatccgtgg aatgattatc gataatgatt aggttgaaag
     4081 ggaaggacgc ctcttgtcgc agtacggaac ggatagcgtc ctcgatcgtc cgtacacggt
     4141 tacgtaccgg gataataacg gaggcttccg tttgaaatgt ctgctcgtca aaacggactg
     4201 gcttgaaatg agggggcaag tagccgccta tcatctttaa gtgatctgta caggcggctt
     4261 ccatctcgat ctgtacggag cggttcttgg gatctacata gtcgaacatc ttctctccgg
     4321 atttccgtaa atcattctct acttctgtat atagatattc gttgatatgc gtcagcggag
     4381 cgttttggga gactttcagg cgcaagtcgt agagtccggc gaatgtatat tccgtatcca
     4441 tggaggctat ggcgttttgt agcgtggaag aacgatagag taggagggag ccgaaattga
     4501 aatcatccct aagacttcct ttctggtaat cgatcaccgg atgggggttg agtttgccct
     4561 ccttcttctc gtaataatcg gagtaaacca taccggatct cgtatcgtcg gcgatggcga
     4621 caaaacgctc tagggcatac atgcctaatt gaagctcttc agtcttcgta taaattaacg
     4681 tataatgggc actggcatag ccggctattt cccggagggt cttcgtgctc catatattct
     4741 ccgtgcggat taaattgcag ggataaatag ccttggcgtg gggatcgtcc gtgattagat
     4801 agatctgact cactaaggac gactcggcca attgcgctac cgtttgtcgt gtagcctcta
     4861 tttttccata agggataaag caattgattc gtttcattgt atatactgta ttttattttg
     4921 ttgttgaatg gagaaaaagc gtaagatgga ctccatgagt cgatttcgtt ccgacggtgt
     4981 ttgaagtgcc tcaaacggga aaccgagcga acaagtccga tatttccctt cataaacgat
     5041 tcccgccccg atattgttct ccggatatct caagatggta tgggcgagct tatccgccgg
     5101 aagtacaccg tctaccgact cgatcgagta gcaaataggg ttcggacgtg tccggaacgt
     5161 gtatctgccg tttatatatc cgtaagggga tgcgcaactg tttacgattc cctccttgct
     5221 ggcattacgg ctagccaact tcccttttag tacctcctcg acgaacgtac ggtcttgtgc
     5281 gttgccccag ctgtcggaga aaagattcgt cccgcttaca agcaagttgc cgccttgggc
     5341 aaggtaactg cgaagtgtat cctgtaaaac gggagtgata accggttggc gctgttttcc
     5401 taaaatcaag tcaataatcg gatacgtatc cggctttacg actccctcgg ccaaagattt
     5461 atggctacat gaaacaaagg aataaccggt cccggccatg gcctgcccat gtatgaaagg
     5521 ataatcgaag gtattgcccg ctatgacttg gcctgcgtaa ttgttgtaac tatccccatg
     5581 cccgttatta tcattgctgt tccatgtggc ggaacggcgg aattcgaatt gatccccgat
     5641 aaatgcgata tcattcagat aaggcactcc ccggtcgacg gcataaagaa agccggctaa
     5701 actatccgcc gtactctcga aactggctgg accgctgatc ctgtcgaatc cattgacgat
     5761 caataccgtc ttatcctttt cacctttagg agaccggtaa acacttacga tctcggaagg
     5821 gaaactgatg cctcccttat ttacggcagc taccttataa ctatggataa tacccgtctc
     5881 aattggaaga atgatttctt ctccttttac gagcgtcccg ttatcgaatc caccgctgtc
     5941 ttttcgacta taaaggatat aggcggttgg tgaggcactc tcctcaagag tatcctgtac
     6001 ggctttccag ccgattctca ctttattcgt ttctacgagc tccgtataca gacgatcggg
     6061 tgggagcggt tgtacgatag gctcctgttt attctggaaa cagatataac ggagcatccc
     6121 tttatagatc gccctacaaa taaggaaacg gaagcgtggg tctaacccgt aacgcatatc
     6181 ggcgaagttt tgatgggata gtaattctaa tagcatcgtt gggacatcgg gaatacgtgc
     6241 ctctatataa gattgattcc acatgccccg gcggctccat tgaggattgt aaaccttgcg
     6301 gacatcggac aggatctgtg tttggatcat gtcggttagg tctctggcga tctcccggct
     6361 tttccggttg gtgtagattc cgtcgttgct tttagacata tagatgccga gtgtccctat
     6421 aattgagtca tccggggtgg ttcctgcgtc ggaatggaat gcgaaggcca tgtcgatagg
     6481 gatatgggtc tgttctttta aataattaac ccattgggga cgtgcgtaaa tgtcgtcttg
     6541 ataatcattg cggaaagcgc ttttcgaata gatactatcc ggtattcccg cccattgtag
     6601 ccaatatcgg gccgcctcgg taaaccgtgg atacccactt gtctctgctt ctatcggata
     6661 gggactttct agcgggctac gtgcgatgtt ccccatgccg ccaccgatct tgattgcgtc
     6721 tgccgtgata atctttcccg atttattgct ttgattcgtt aatacgattc tctcatgggc
     6781 ttgttcatgt gccgtgaatt tgaagtttcc cagatagatc caagtcccac cccccattgt
     6841 ttgattgacg gcgattgtgg tttcccctcc ggcatgatgg atggtataca gtgcctgctc
     6901 tgtgctgttc ggaaaagatt gataggaggc atagaccgcg taattccccg attccggaat
     6961 ttcgggaatc cactcgatga gactttcttt tcctttcctc tgtgtgaccg tctgccgata
     7021 ggtaccttgc gtaaaagggt tctccccatt cgtataagta gcttgaatat gcccaaatcc
     7081 ggctttctcc ccatccgacc aagctttctc tccatccaat tccttatact cggatcccgg
     7141 agtagagcga tcattgtcga taatgatttc gtgtatttga gtgtcccttt cccgggggat
     7201 aagaatagtc gctcctgcgt tttcaagcat cggggtcaga taaggaagaa caaaactctg
     7261 cgtaaataag tcctccacgg tgccgaacat gcgagcccgt tgccattccc agcgatgggc
     7321 ggtctgggcg taatataaac catggctttg ccaaagggcg atatgacggt tttgtaatcc
     7381 gttttttatc tcatgagggg tggataggct acgggttagc gggtatttac tctctttaat
     7441 ggagtatagc ctctttttgt tgggacgtcc ttttctgtcg tattcgggaa tcaagctctc
     7501 aatgtctgta tctcgggtca agatgacgat cttggaggca ttggggaata ggggagctat
     7561 acttgcgtaa agctcagaaa cgttgtattc ccgaaaaggg atgtcctcca aagcttcatt
     7621 ggcgaaaagc gtgactttct tcttctgtat gaggatggag tcaatcttaa tggtgcgtga
     7681 agacacatat tgccttgcga aagagtttag cttttgatct aattgctttt ttaagctttc
     7741 actatcctgc ccttctgccg gaaagctcca gagaaaaatg gatagtaagg atatgatgat
     7801 cctaacagga taggagagtt tttctcgcat atttttataa atattattgg ctgtcttatt
     7861 tctacaaatt tacggaaaat ctccgtaata accttataaa aagcccagat tggcgcaatt
     7921 aaaattgaat atgaagaagg taggggcaaa ttgtggatat tgggagaagt caaatttatg
     7981 tgaacggcag caaggagaag aacggatttg tccctatcat gggacgggta gcgattaacg
     8041 ggacgatggt gcggttcagt tcagttgcga gcgaactatt cgtgttcatg gtcaagacgc
     8101 ctatctgggg aatgattatc ccttcttgaa gtgtcgggtt tgcgatagta tctcaatggg
     8161 aaacggtggt aaagtcaatg ggatagaggt gttatctcaa tgactttacg gccgtgtccc
     8221 ataggctttt tttgtatccc tgataagttg gtaggggatg gttcagggcg caaagggcgc
     8281 atctttgcga ggtttgtaaa acttttatat tataaaaaaa ttagcgtctt acttatatat
     8341 agatggagta atatattttt ttttgtaaaa tgtttttgcg aacacgtaaa gatgcgccct
     8401 aatgcgccct gtgatttttt tggaagattt tcttgatgtc ttaaagtata gatagacagt
     8461 tgtttatgta atactgttct cttagccctt ttttagtctt tggggcgata taatcggcct
     8521 aaactcacat tgtacgtggc ccaaaagcac gtgtacagag cgattttctc gtgattccat
     8581 gagcagaaag ccgtttttcc cgtgtgattt cctctcgtcg ccaggacctg tttatcgttt
     8641 ttatacgtgt aaaagcactc gtgagagccc tgttttcggt acacgtggtg actcgtaagt
     8701 taaaaaagag cgtcacgtat tatttcaatg tacgcaatcc ccctcatgaa aaaaatattg
     8761 caaaaaaatt ccgaaaaagt ttggaggtta tgttttataa cactactttt gcacccgcat
     8821 ttgagagaga acgccggtac aaaatgatga aacaaacttt tagaaaaaaa agttccggaa
     8881 taatttggaa gtttaaaata aaagtcctta cctttgcagc cgcaatcgag aaacgatagc
     8941 gacaagagtt ctttgataga tttacataat tcaacaagta gtacaagtat tggagaagag
//
LOCUS       DBMDTB010000131         8806 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_2194_length_8806_cov_11.076048, whole genome shotgun sequence.
ACCESSION   DBMDTB010000131 DBMDTB010000000
VERSION     DBMDTB010000131.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 8806)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 8806)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8806
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2194_length_8806_cov_11.076048"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            594..1409
                     /locus_tag="ACZPB4_15235"
     CDS             594..1409
                     /locus_tag="ACZPB4_15235"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009101 - glycoprotein biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HIR1099607.1"
                     /translation="MQSFSVLLSLYHKESALFLHQSLESVFAQTLLPTEVILVEDGPL
                     SEELHAVVKEFMDRYLELKVIPLVENQGLGKALNEGLKHCSYDIVARMDTDDVAKPDR
                     FEKQLAIFQEHPEVDVVGAWIDEFEGAVSNVLSVRKVPKDQEDILRFAKGRCPVNHPV
                     VMFRKSAVLKAGGYKHFPLFEDYYLWVRMLMDGARFYNIQESLLFFRFSPDMFKRRGG
                     WRYAVTEVKLQTLFYRIGFIDFFSLIRNICIRLVTRLLPNDFRSLLYKRFIRN"
     gene            complement(1555..2145)
                     /locus_tag="ACZPB4_15240"
     CDS             complement(1555..2145)
                     /locus_tag="ACZPB4_15240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017140816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative polyvalent protein kinase
                     domain-containing protein"
                     /protein_id="HIR1099608.1"
                     /translation="MDRAYSPINNLLEQAACIARRSKETAGEIEPTEGYKRRQINELI
                     KFTNNRNLWVNLSCLTLTYMDKGGENEVFHDGKVSVIKLNNFEYAGDDLENFFIRITV
                     HNKFFSNVPYQMIGFAYNSEQKFCAVLIQPYILAEREATEDEIAAYMQALGFKMDYYD
                     EYHNEDYEVFDAAPNNVLYGIDGNLYFIDTQIRLKS"
     gene            2540..4426
                     /locus_tag="ACZPB4_15245"
     CDS             2540..4426
                     /locus_tag="ACZPB4_15245"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HIR1099609.1"
                     /translation="MEVLKHECGVAMVRLLKPLEYYHEKYGSWMYGLNKLYLLMEKQH
                     NRGQEGAGLACVKLEANAGEEYMFRERAVGTGAITEIFAAVHEHYKDLTPEQLNDPLF
                     AKANLPFAGELYMGHLRYSTTGKSGISYIHPFLRRNNWRAKNLAVCGNFNLTNVHEVF
                     EEITAIGQHPRKYSDTYIMLEQLGHRLDREVERLYQKCEAEGLRGMDITHAIEDQIDL
                     SNVLKRCTPGWDGGFVICGITGSGESFSVRDPWGIRPAFYYADDEIIVLASERPVIQT
                     VMNVQVEDIRELNRGEAILVNKKGEWHISQIVEPKENKACSFERIYFSRGSDVDIYRE
                     RKRLGDNLVHPILKAVDYDLNHTVFSFIPNTAEVAYFGMQEGLNNYLNKLKKEWIADR
                     SHLLREEELEQILSMRIRSEKVAIKDIKLRTFIAEGNSRNDLAAHVYDITYGSIEPFI
                     DNLVVIDDSIVRGTTLRQSIIGILDRLHPKKIVIVSSSPQVRYPDYYGIDMSRMNEFI
                     AFKAAVALLRDRRMEYVILDAYQKAKRQQTAADGPLVNYVKEIYAPFTDEEISVKMVE
                     LLTPAGTQAKVEIVYQTLEGLHASCPEHPGDWYFSGDYPTPGGTRLVNEAFIHYMEEE
                     YLVK"
     gene            4423..5604
                     /gene="carA"
                     /locus_tag="ACZPB4_15250"
     CDS             4423..5604
                     /gene="carA"
                     /locus_tag="ACZPB4_15250"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HIR1099610.1"
                     /translation="MTQHTDSMQTNRTATLMLDDGTVFRGYSFGYERPVAGEVVFNTA
                     MTGYPESLTDPSYAGQLMVLTYPLVGNYGVPPRTFEPNGIATFMESEKIHAEAIIVSD
                     YSHEYSHWNAECSLGDWLKEEKIPGIYGIDTRALTKKLREHGVMMGRIVIGDADNEIE
                     NGELKIENYEHVNYVDRVSCKEIICYLPDGTSQTCSLSEASNSRFSILDSQFLKRVVL
                     LDCGVKHNIIRCLLRRNVAVIRVPWDYDFNQLEYDGLFISNGPGDPDTCDAAVRNIRK
                     ALSGDKPICGICMGNQLLAKAGGASIYKLKYGHRSHNQPVRMVGTEKCFITSQNHGYA
                     VDNDTLGEEWEPLFINMNDGTNEGIKHKTKPFFSSQFHPEACSGPLDTEFMFDKFADL
                     L"
     gene            5678..>8806
                     /gene="carB"
                     /locus_tag="ACZPB4_15255"
     CDS             5678..>8806
                     /gene="carB"
                     /locus_tag="ACZPB4_15255"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005675690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005951 - carbamoyl-phosphate synthase
                     complex [Evidence IEA];
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) large subunit"
                     /protein_id="HIR1099611.1"
                     /translation="MKEDIKKVLILGSGALKIGEAGEFDYSGSQALKAIKEEGIQTVL
                     INPNIATVQTSEGVADTVYFLPVTPFFVEKVIEKERPEGILLAFGGQTALNCGVALYQ
                     SGVLEKYGVKVLGTPVQAIMDTEDRELFVRKLDEIDVKTIKSEAVENAADARRAAAEL
                     GYPVIVRAAYALGGLGSGFCDNEEELDVLVEKAFSFSPQVLVEKSLKGWKEVEYEVVR
                     DRFDNCITVCNMENFDPLGIHTGESIVIAPSQTLSNTDYHKLRELAIRIIRHIGIVGE
                     CNVQYAYDPESEDYRVIEVNARLSRSSALASKATGYPLAFVAAKLGLGYGLFDLKNSV
                     TKTTSAFFEPALDYVVCKIPRWDLGKFHGVARELGSSMKSVGEVMAIGRTFEEAIQKG
                     LRMIGQGMHGFVENKELVIEDIDKALHEPTDRRIFVISKAFRAGYTVDQIHELTKIDR
                     WFLQKLYGIMQTSKELHAFDMKGIQRWRINPELIRRAKIQGFSDFQIARAIGLDGDVE
                     KGMMLVRQFRKEHGILPVVKQIDTLAAEYPAQTNYLYLTYSGTENDVTYLGDHRSIVV
                     LGSGAYRIGSSVEFDWCGVQALNTIRKEGYRSVMINYNPETVSTDYDMCDRLYFDELT
                     FERVMDILELENPHGVIVSTGGQIPNNLAMRLDEQHVNILGTSAKSIDNAEDREKFSA
                     MLDRIGVDQPRWKELSSMEDINGFVAEVGFPVLVRPSYVLSGAAMNVCSNQEELERFL
                     KLAANVSQKHPVVVSQFIEHAKEVEMDAVADHGEIVMYAISEHIEFAGVHSGDATIQF
                     PAQKLYVETVRRIKRISKQIAKELNISGPFNIQYLAKGNEIKVIECNLRASRSFPFVS
                     KVLKINFIELATRVMLGLPVEKPNKNEFDLDYVGIKASQFSFNRLQKADPVLGVDMAS
                     TGEVGCLGDDVSEAVLTSMLAVGQRVPEKNILLSTGTPKQKVAMLDAAKMLAAKGYNL
                     FATGGTHRFLAENGIPSTKVYWPSEKGEPQALKMLHEKQIDMVVNIPRDLSAGELDNG
                     YKIRRAAIDLNIP"
BASE COUNT         2190 a         1785 c         2388 g         2443 t
ORIGIN      
        1 ttattgcatg cgcatggtga ttatattttt agcagatcaa gatgatgtat ggcataaaaa
       61 taaggtgagt gtttgttttt cttatttaga taatatatgt tgattcaaca tgaccgaaca
      121 cttataggaa attcgtatgg ctatcctttg catgtgaaaa gcatccataa attatttttt
      181 ttgaatttgt ttgatttatc gttcaaagga tgttgcatag cttttcgacg agaattgtta
      241 caaaaagtat tgcctgttcc aaagccagtg attgtccatg atgcttggat tggctgttgg
      301 ggttatttgt tgggtagtta tgtctcgata aatgatgaac tgatagatta tagagttcat
      361 ggaaaaaatg tatcaatagg tacaaggaat aggttttact ataaaatatt gtatagactg
      421 caaatttgtt attgtttgtt taagcgttca tttttctaaa tgatgagaca tacgatagtt
      481 tgtattgtag cttgtttcct tgtttttaac gagtgattaa aatctttttt tattttaatt
      541 caagatgtgt tctgattgga acactaatgg ttaatcaatt ttccctatat tttatgcaat
      601 cattttctgt attgctttcc ttatatcaca aggagagtgc attattcctg caccaaagtc
      661 tggagagtgt ctttgcacaa acactattgc ctaccgaggt gattttggtg gaggatggac
      721 ctttgtccga agagttgcat gcggttgtaa aagagttcat ggatcggtat cttgaattaa
      781 aggtgattcc tttggtagaa aatcaaggtt tggggaaagc tttgaacgag ggtttgaaac
      841 attgctcgta tgatatcgtg gctcgcatgg atacggatga tgtggcgaag ccagaccgtt
      901 ttgaaaagca gttggcgata tttcaggaac atccggaagt ggatgtagtg ggagcttgga
      961 tcgatgagtt tgagggagcg gtatccaatg tcctttctgt gcgtaaagtg ccaaaggatc
     1021 aggaagatat cttgagattt gcaaaaggaa gatgtccggt gaatcatcct gtggtgatgt
     1081 tccgaaagtc ggctgtattg aaagctgggg gatataagca ttttcctttg ttcgaggatt
     1141 attatttatg ggtacggatg ttgatggatg gtgctcgatt ctataatatt caagagagtt
     1201 tacttttttt ccgtttttct ccagatatgt ttaagcggag ggggggatgg aggtatgccg
     1261 taacggaggt gaaattacag actctgtttt ataggatagg ttttatcgat tttttctcct
     1321 taataagaaa tatctgtatt cgtttggtga ctcgtcttct ccccaatgac tttcgctctt
     1381 tactttataa gagatttata cgaaattaaa ttattctttc gctttatttc gtatatccgt
     1441 acggtgattt cccaaagctt ttttgtgtta gagatcccat ggtaaggcct cccctaaaag
     1501 gaggcttttt tgtttccgga aacatcgcat tatgacttcc ggctttgttg tcatctatga
     1561 ttttaatctt atctgtgtat caataaaata caaattccca tctataccat aaagcacatt
     1621 gttaggggct gcgtcaaaca cttcataatc ttcattgtgg tattcgtcgt aatagtccat
     1681 tttaaagcca agagcttgca tataggcggc tatttcatct tctgtagctt ctcgttccgc
     1741 taatatataa ggttgtatga ggactgcaca gaatttttgc tcgctgttat atgcgaagcc
     1801 aatcatctga taaggtacat tactgaaaaa cttgttatgt acagtaatgc gaatgaaaaa
     1861 gttctccaag tcatcaccag cgtactcaaa gttatttagc ttgattacag agaccttacc
     1921 atcatgaaat acttcattct caccaccttt gtccatatag gtgagagtga ggcaggataa
     1981 gttaacccat agatttctat tattagtaaa ttttattagc tcattgattt gccttctctt
     2041 atagccctct gttggttcaa tctctcctgc tgtttcttta cttcttctgg cgatgcaggc
     2101 tgcttgctcc aagaggttat tgattggcga gtacgctcta tccattgttt gtgaaattcg
     2161 ttaatatatt ccataaatca ttttactaag agttcatggc aaaggtaatc tttctatttt
     2221 aatatcgtaa tgatttgtct gtaactttgt aaggttacat tataaaaatg tatggagagt
     2281 ttacttcatg catattgtaa atttccagtc ggctaagaat ggaatgtatt gcctgaaaca
     2341 ttatgcctcc cttctttgtt atatcttatt atggattgaa aacaaaccct cccttttgct
     2401 tataaaatgt aagctttgtt aaccaaacgt ccgataaaaa cattttttcc gtgaaagtgt
     2461 caattatttt atgtttgttt aaacaatatg ttaggtattg tctgtatctt tgcggcaaaa
     2521 tcaaaaagtt gattcgacaa tggaagtatt gaagcacgag tgtggtgttg ccatggtccg
     2581 gttactgaaa cccttggagt attatcacga gaagtacggt agttggatgt atggactgaa
     2641 caagctctat ttgctgatgg aaaagcagca taacaggggg caggaaggag cgggcttagc
     2701 ctgcgtgaag ttagaggcaa atgccggaga ggaatatatg ttccgtgaac gggccgtcgg
     2761 gaccggagct attaccgaga tatttgccgc agttcacgaa cactacaagg atttaacccc
     2821 cgagcaactc aacgatccgc tattcgccaa agccaaccta cctttcgccg gagagcttta
     2881 tatgggccac ctccgttaca gtaccaccgg aaaatccgga atctcttata tccatccttt
     2941 tttacgacgc aataactggc gtgcaaagaa ccttgccgtt tgcggaaatt tcaacctgac
     3001 aaatgttcat gaagtattcg aggagatcac ggcgatcggt cagcatcccc ggaaatattc
     3061 cgatacgtat atcatgctgg agcagctggg acaccggctg gaccgggaag tggagcgcct
     3121 gtaccaaaag tgtgaggcgg aaggattgag agggatggat atcacgcatg ccatcgagga
     3181 tcaaattgat ttgtcgaacg tgctgaaacg ctgtaccccg ggctgggatg gtggtttcgt
     3241 gatttgcggt atcaccggta gtggcgagtc gttcagcgtg cgggacccgt ggggaatccg
     3301 tccggccttc tattatgcgg atgatgagat tatcgtgttg gcttccgagc gtccggttat
     3361 acaaaccgtg atgaacgtgc aggtagagga tatccgggag ttgaatcggg gagaggcgat
     3421 actcgtcaac aagaaaggcg agtggcatat ctcccagatc gtggagccga aagagaataa
     3481 ggcttgttcc ttcgagcgta tctacttctc acggggtagc gacgtggata tttacaggga
     3541 aaggaagcgt ttgggagata atctcgtgca tccgatcttg aaagcggtgg attacgactt
     3601 gaatcatacc gtcttctctt ttatcccgaa tacggccgag gtcgcttatt tcgggatgca
     3661 ggaggggttg aacaactatt tgaataagct gaaaaaagaa tggatcgccg atcgtagtca
     3721 cttgctcagg gaagaggaac tggagcaaat cctttccatg cgaatccgct cggagaaagt
     3781 agctataaaa gatataaaat tacgtacatt tatcgctgag ggcaatagcc gcaatgatct
     3841 ggcggcgcac gtgtatgata ttacttacgg aagtattgaa ccttttatcg ataatctggt
     3901 tgtgatagat gatagcatcg tgcggggtac taccttgcgc cagagtatta tcggtatctt
     3961 ggatcgcctg catccgaaga aaatcgtgat cgtaagttct tctccacagg tacgttaccc
     4021 ggattattac ggtatcgata tgtcccggat gaacgagttt atcgctttta aggctgcggt
     4081 ggccctgtta cgtgaccgga ggatggaata cgtgatcttg gacgcttatc aaaaggcgaa
     4141 gcgacaacaa acagcggcgg atggtccgtt ggtgaattac gtaaaggaga tatacgcccc
     4201 gtttacggac gaggagatat ccgttaagat ggtggagttg cttacaccgg ccgggacgca
     4261 ggcgaaagta gagatcgtct accagacttt ggagggcttg catgcctctt gtccggagca
     4321 tccgggtgac tggtatttct ccggcgatta cccgacaccg ggcggaactc ggttagtgaa
     4381 cgaggctttt attcactata tggaagaaga atatttagtg aaatgacaca acatacagat
     4441 tctatgcaga caaacagaac agcaactttg atgttagacg acggtaccgt cttccgtggc
     4501 tactcttttg gctatgagag accggtggct ggcgaggtcg tgttcaatac cgctatgacc
     4561 ggatatccgg agagcttgac ggacccttcg tacgcaggcc agttgatggt gttgacttat
     4621 ccgctcgttg gtaactacgg tgtcccgcct cgtacgttcg agccgaacgg gatcgctacg
     4681 tttatggaga gcgagaagat ccacgccgag gcgattatcg ttagcgatta cagccatgag
     4741 tatagccact ggaacgccga gtgcagcttg ggcgactggt tgaaggagga gaagatcccg
     4801 ggcatatacg gtatcgatac gcgtgcgttg actaagaaat tgcgtgagca tggcgtgatg
     4861 atgggacgca tcgttatcgg cgatgccgat aacgaaattg aaaatggaga attgaaaatc
     4921 gagaattatg agcatgtgaa ctatgtggat cgggtatcgt gcaaagagat tatttgttac
     4981 ctgcccgatg gtacgagcca gacctgttct ttatcggaag cctccaattc ccgattctcg
     5041 attctcgatt ctcaattcct aaagcgcgtc gtgcttttgg actgcggcgt gaaacataac
     5101 atcatccgtt gcctgttgag gcgtaacgtg gcggtgatcc gtgtgccttg ggactacgac
     5161 ttcaatcagc tggaatacga tggcttgttt atcagcaacg gtccgggcga tccggatact
     5221 tgcgatgccg ccgtgcggaa tatccgtaag gcgctttccg gggataagcc gatttgcggt
     5281 atttgcatgg gtaaccagtt gttggcgaaa gccggcggtg cttctatcta taaattgaag
     5341 tacggtcatc gtagccataa ccagccggta cgtatggtag gcacggagaa atgcttcatc
     5401 acctcgcaga accatggtta cgccgtggat aacgatacgc tgggtgagga gtgggaaccg
     5461 ctgttcatca atatgaatga cgggacgaac gagggtatca agcataagac gaagcctttc
     5521 ttctcctctc agttccatcc cgaggcttgc agcgggccgc tggatacgga gttcatgttt
     5581 gataagttcg cggacttact gtagccccgt tcgtttccgg gtgccggaat aacccgtttc
     5641 cgggtgtcgt aaatacaaac attaaaaaaa tgaagcaatg aaagaagata taaagaaagt
     5701 cctgatactc ggcagcggag ccttgaagat tggtgaggcg ggcgagttcg attattcagg
     5761 cagccaagcc ctgaaggcga ttaaggaaga ggggattcaa acggtattga tcaatccgaa
     5821 tatcgctacg gtacagacct cggaaggagt cgcggacacg gtttatttcc tgcccgttac
     5881 tccttttttt gtggaaaagg tgatcgagaa ggaacgtccg gaaggtatct tgctcgcttt
     5941 cggcgggcag acggcgttga attgtggcgt ggctctttac caaagcggcg tgctggagaa
     6001 gtatggcgtg aaggtattgg gtaccccggt gcaggctatc atggataccg aggatcggga
     6061 gttgttcgta cgcaagctgg atgagatcga cgtgaagacg atcaagagcg aggccgtgga
     6121 gaacgccgct gacgctcgtc gtgcggccgc tgagctgggg tatccggtca tcgtccgtgc
     6181 cgcttatgcg ctggggggct tgggttccgg tttctgcgac aatgaggaag aattggacgt
     6241 gttggtagag aaggctttct ctttctctcc gcaagtattg gtggagaaaa gcttgaaggg
     6301 ctggaaagag gtagagtacg aggtggtgcg cgaccgcttc gataactgca tcacggtatg
     6361 taacatggag aatttcgacc cgctgggaat ccatacggga gagtctatcg tgattgcccc
     6421 ctcgcagacc ttgagcaata cggattatca taaattacgt gagttggcga tccgtatcat
     6481 tcgccatatc ggtatcgtgg gcgagtgtaa cgtgcaatac gcttacgatc cggagagtga
     6541 ggattaccgg gtgatcgagg tgaacgcccg cttgagccgt tcttcggcct tggcttctaa
     6601 ggcgaccggt tatccgttgg ctttcgtggc cgctaaatta ggcttgggct acggtttgtt
     6661 cgacttgaaa aactccgtga cgaaaacgac tagcgctttc tttgagccgg ctctcgatta
     6721 cgtggtatgt aagatccctc gctgggactt gggtaagttc cacggcgtgg ctcgtgagtt
     6781 gggttccagc atgaagtcgg ttggcgaggt gatggcgatc ggacgtacct tcgaggaggc
     6841 tatccagaag ggcttgcgta tgatcgggca gggtatgcac ggtttcgtgg agaataagga
     6901 gttggtgatc gaggatatcg ataaggcgtt gcacgagcct accgatcgcc gcatcttcgt
     6961 tatctcgaag gcattccggg ccggttatac ggtagaccag attcatgagc ttaccaagat
     7021 agaccgatgg ttcctacaga aactatatgg aatcatgcag acctccaagg agcttcacgc
     7081 tttcgatatg aaggggatcc aacgttggcg catcaatccg gagttgatcc gccgggcgaa
     7141 gatacaaggg ttctctgatt tccagatcgc ccgtgcgatc ggtctcgacg gggatgtgga
     7201 gaagggtatg atgttggttc gccagttccg taaggagcat ggcattcttc cggtggtgaa
     7261 acagatcgat accttggccg ccgagtatcc ggcgcagacg aattacctgt acctgacgta
     7321 tagcggaacg gagaatgacg tgacgtactt gggcgatcat cgctcgattg tcgtgctggg
     7381 ttccggcgct tatcgcatcg gtagctcggt ggagttcgac tggtgtggcg tgcaggcctt
     7441 gaatacgatc cgtaaggagg gctatcgttc cgtgatgatc aactacaatc ccgagacggt
     7501 gtctaccgac tatgatatgt gcgatcgtct ttatttcgat gagcttacct tcgagcgtgt
     7561 gatggatatc cttgagctgg agaaccccca cggcgtgatc gtctccaccg gcggccagat
     7621 cccgaataac ttggcgatgc gtttggacga acagcatgtg aatatcttgg gtacgtcagc
     7681 taagagcatc gataatgccg aggaccgtga gaagttctcc gccatgttgg atcgtattgg
     7741 cgtggatcaa ccccgctgga aagagctttc ttccatggag gatatcaatg gtttcgtggc
     7801 ggaggtaggc ttccccgtgt tggttcgccc gagttacgtg ctgagtggtg ccgccatgaa
     7861 tgtctgctcg aatcaagagg agttggagcg tttcttgaaa ttggccgcca acgtcagcca
     7921 aaagcatccg gtggtggtaa gtcagttcat cgagcatgcg aaagaggtgg agatggatgc
     7981 cgtggccgat catggcgaga tcgtgatgta tgccattagc gagcatatcg agtttgccgg
     8041 ggtacattcc ggcgacgcta cgattcagtt cccggcccag aaattatatg tggagacggt
     8101 tcgtcgtatc aagcgtatca gtaagcagat cgctaaggag ctgaatatct ccggcccgtt
     8161 caatatccaa tatctggcga agggcaatga gatcaaggtg atcgagtgta accttcgtgc
     8221 cagccgttcc ttcccgttcg tgagcaaggt gctgaagata aacttcatcg agttggctac
     8281 ccgtgttatg ctgggcttgc cggtagagaa accgaataag aatgagttcg atttggatta
     8341 cgtgggtatc aaggcctctc aattctcgtt caatcgcttg cagaaagccg atccggtatt
     8401 aggggtcgat atggcttcca cgggcgaggt gggttgtctg ggcgacgatg tatccgaggc
     8461 ggtgttgacg agtatgctcg ctgtcgggca acgggttccg gagaagaata tcctcctgtc
     8521 caccggtacg ccgaagcaga aggtagccat gctggatgcc gctaagatgc tggcagcgaa
     8581 aggctacaat ctattcgcta cgggaggtac acaccgtttc ttggcggaga atggcattcc
     8641 gagtacgaag gtgtactggc cgagcgagaa gggagaaccg caggcgctta agatgcttca
     8701 tgagaagcag atcgatatgg tcgtgaatat ccctcgtgac ctttccgccg gcgagcttga
     8761 caacggctat aagatccgcc gtgccgccat cgacctgaat atcccg
//
LOCUS       DBMDTB010000132         8532 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_2259_length_8532_cov_11.168545, whole genome shotgun sequence.
ACCESSION   DBMDTB010000132 DBMDTB010000000
VERSION     DBMDTB010000132.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 8532)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 8532)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8532
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2259_length_8532_cov_11.168545"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..1544)
                     /locus_tag="ACZPB4_15260"
     CDS             complement(<1..1544)
                     /locus_tag="ACZPB4_15260"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HIR1099612.1"
                     /translation="MNIKSKFGYLCCASLLTTSLWAQDVLISTRNTSLLLDAPVGGEV
                     RFIYYGDKLSTSDAATLLETEQKTFSAYPVYGLNCPSESALSVTHGDGNMTLQLEVIK
                     VDTRKEQTADITTIRLKDKVYPFYMNLCYRTYPDADIIETWTEITHEEKKAITLNRFA
                     SAYLPIRKGDVWVSHLYGSWANEAQLAQEPLRPGIKMIKNKDGIRNSHTAHAEVMISL
                     DGKPKENTGSVIGAALCYSGNYKLFFDTDDSDYHHFFAGINEENSAYTLKAKESFRTP
                     ELALTYSKDGLSGSSRNFHAWARKHKIANGATARKILLNSWEGVYFDINQEGMDQMMS
                     DIQSMGGELFVMDDGWFGDKYPRNKDNSSLGDWMVDARKLPRGIEGLIADANKHGIKF
                     GIWIEPEMANTTSELYEKHPEWVLKAPNREIVLGRGGTQVVLDLSNPEVQDFIFGIVD
                     NLMTTYPEIDYIKWDANMSILNHGSQYLPSDQQSHMYIEYHEGFKKVCERIRAKYPDL
                     TLQACA"
     gene            1770..5192
                     /gene="ileS"
                     /locus_tag="ACZPB4_15265"
     CDS             1770..5192
                     /gene="ileS"
                     /locus_tag="ACZPB4_15265"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HIR1099613.1"
                     /translation="MSKKFTEYSKFDLSNVNKEVLKKWKDGDIFHKSLETREGHPTFV
                     FYEGPPSANGMPGIHHVIARSIKDIFCRYKTMKGFLVNRKAGWDTHGLPVELGVEKAL
                     GITKEDIGKKISVAEYNAACRKDVMKFTKEWEDLTQKMGYWVDMENPYITYDNRYIET
                     LWYLLKELYKKGLLYKGYTIQPYSPAAGTGLSTHELNQPGCYRDVKDTTCTAQFHILD
                     PKPEMAQFGDPYFLAWTTTPWTLPSNTALCVGPNITYLAVQTYNPYTGIPMTAVIAKD
                     LLSAYFNPKAAELSLSDYKPGDKLVPFSVVGEWKGSELAGMKYEQLIPWVNPGEGAFR
                     VITGDFVTTEDGTGIVHIAPTFGADDNRVAKTFGVPPLMMQDKDGNMRPMVDMTGKFY
                     KLEDLAPEFVQNCMNASDYDPWQGKFVKNAYDDTKTDKDETLDIEICMMLKAQNRVFK
                     IEKHVHNYPHCWRTDKPVLYYPLDSWFIRTTACRERMIELNNTINWKPQSTGTGRFGK
                     WLENLQDWNLSRSRYWGTPLPIWRTEDGSEEKCIGSVVELFGEIEKSVKAGFMESNPY
                     KDFAPGDYTKENYEKIDLHRPYVDDIILVSASGKPMKRETDLIDVWFDSGAMPYAQIH
                     YPFENLEEFDNRQIYPADFIAEGVDQTRGWFFTLHALGTMIFDSVAYKAVVSNGLVLD
                     KNGNKMSKRLGNAVDPFSTIEKYGSDPLRWYMITNASPWDNIKFDIDGIEEVRRKFFG
                     TLYNTYSFFALYANVDGFDYSDPDVEWSKRPEIDRWILSLLNSLVKDVDGYLEAYEPT
                     RAGRAISDFVNDNLSNWYVRLNRRRFWGGGMTEDKLSAYQTLYTCLETVAKLMAPIAP
                     FYADQLFLDLVAVTGRENVESVHLSDFPVYDESKIDKNLEERMQMAQDVSSMVLALRR
                     KVNIKVRQPLHTVMIPVVDAHQQESIEAVKNLILNEVNVKELKFVDNTAGILVKKIKP
                     DFKKLGPRYGKIMKALAATIQSMSQEDINAFEKAGTFTLMVDGQEAVLERTDVEIISE
                     DIPGWLVANEGRLTVALDITVTEDLRKEGLARELVNRIQNLRKSSGFDITDKIHVSIL
                     SCEEMDEAIYDYKDYIANQVLAESIEIMDNAISDATELDFEDFKLSVKIEKA"
     gene            5360..5740
                     /locus_tag="ACZPB4_15270"
     CDS             5360..5740
                     /locus_tag="ACZPB4_15270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005654117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA family transcriptional regulator"
                     /protein_id="HIR1099614.1"
                     /translation="MAEKTRYSDAELEEFRAIILEKLEIAKRDYELLRSGVTNSDGND
                     VADTSPTFKVLEEGASTLSKEEAGRLAQRQMKFIQNLQAALIRIENKTYGICRETGKL
                     IPKERLRAVPHATLSIEAKQGGAK"
     gene            5741..6358
                     /locus_tag="ACZPB4_15275"
     CDS             5741..6358
                     /locus_tag="ACZPB4_15275"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein signal peptidase"
                     /protein_id="HIR1099615.1"
                     /translation="MRYSKGWGAVLIIILLLLLDQVLKIWIKTHMQLHESIEITPWFY
                     LYFTENPGMAFGIEVIGKLFLSVFRIVAVLFIGYYLYKLVKENYKFGFIACISLVFAG
                     AVGNIIDSIFYGVIFDHSFGQLATFMPEGGGYASWLHGKVVDMFYFPLIETVFPDWVP
                     IWGGQEFVFFRPIFNLADSAICVGVFLLLIFYRHTLSASLSKEEK"
     gene            6359..7144
                     /locus_tag="ACZPB4_15280"
     CDS             6359..7144
                     /locus_tag="ACZPB4_15280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4296 domain-containing protein"
                     /protein_id="HIR1099616.1"
                     /translation="MRRKLRIYGMALLATTLLAACSKVPDGILSEKKMQGVLTDMLLA
                     EAMVNVDYNTYKSDTMKLALYESVFRKHDITQAVYDSSLVWYGRNLDIYMEVYNRVLA
                     DLNKRINNLGDVQADAAPVSNRDSVDIWPRRSYLVLSPTSVFNGVTFDIRPETNYSSG
                     SSFVLGMRVWGLNNKMAYKPEVRLSADQGDTTLTVNSKITKDGYHETILKTIPTKKVK
                     RVFGYIRMDNMDTTYYKVYIDSLSLMKYNYGKELAELPKDSIK"
     gene            complement(7421..8188)
                     /locus_tag="ACZPB4_15285"
     CDS             complement(7421..8188)
                     /locus_tag="ACZPB4_15285"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrmH family RNA methyltransferase"
                     /protein_id="HIR1099617.1"
                     /translation="MLSKTKVKYIRSLELKKFRNENNVFVAEGNKLVADMLPAFECEL
                     LIAKPSWMATQGDIPAKELLVAEEDDIRKASFLKNPQDVLAIFKRPNWDITEITPEKE
                     LVLALDGIQDPGNLGTIIRLADWFGISHIVCSKDTADVFSPKTVQATMGALAHVKIHY
                     TDLETFLQAQSAQAIPLYGTFLGGENLYEKTLSGNGILIMGNEGNGIRPAIEAFVNEK
                     LYIPNYPEGRDTSESLNVAIATAVVCAEFRRRQGNPA"
     gene            8265..>8532
                     /locus_tag="ACZPB4_15290"
     CDS             8265..>8532
                     /locus_tag="ACZPB4_15290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translocation and assembly module lipoprotein
                     TamL"
                     /protein_id="HIR1099618.1"
                     /translation="MMNRSLRICYFICIVLLLASCSTTKFVPDGEYLLDKVEIVSDNK
                     DYKSADLKSYLKQQPNFKVFGLMKWQLFVYDWSGKNEKKWINKQL"
BASE COUNT         2178 a         1668 c         2186 g         2500 t
ORIGIN      
        1 ctggcgcaag cctgtagggt taaatccggg tatttggctc ggatacgctc acagactttc
       61 ttgaatcctt cgtgatattc gatatacata tggctttgct gatccgaagg cagatattgg
      121 gagccatggt tcaggatgct catattggcg tcccatttga tataatcgat ctccgggtat
      181 gttgtcatca agttgtcgac gataccgaat atgaagtctt gcacctcggg attggagaga
      241 tcaagaacga cctgtgtacc gccacgcccc aggacaattt ccctgtttgg agctttcaat
      301 acccattccg gatgcttctc gtacaattca cttgtcgtgt tggccatttc cggctcgatc
      361 cagataccga atttaatacc atgcttgttg gcgtcggcga tcaggccctc gatgcctctt
      421 ggtagttttc gggcatcaac catccaatcc cctaaggacg agttatcttt attacgagga
      481 tatttatcgc caaaccagcc gtcgtccatg acgaacaact cgccgcccat agactggata
      541 tcactcatca tttggtccat accttcttga ttgatatcga aatatacacc ttcccaactg
      601 tttagtaaga ttttccgtgc ggtcgctcca ttcgctatct tatgtttgcg tgcccatgcg
      661 tggaaatttc ggctgcttcc gcttaagccg tccttactgt aagtcagcgc caattccggt
      721 gtacggaaac tttctttggc tttgagggtg taagccgagt tctcctcgtt tattcccgca
      781 aagaaatggt gatagtcgct atcatccgta tcgaagaata atttgtagtt accgctatag
      841 catagggcgg cgccaataac ggaaccggtg ttttcctttg gttttccgtc tagggagatc
      901 atcacttcgg cgtgggcggt atgggagttg cggataccat ccttgttttt tatcatcttg
      961 atgcccggtc gtaacggttc ttgtgccaat tgagcctcgt ttgcccatga gccgtataag
     1021 tgggaaaccc atacgtctcc tttccggatc ggcagataag cggaagcgaa acgattgagg
     1081 gtgatcgctt ttttctcctc atgcgtgatc tctgtccaag tctcgatgat atcagcgtcc
     1141 ggataggttc tgtaacagag attcatataa aaaggataca ctttatcttt taatcggatc
     1201 gttgtgatat ctgctgtttg ctcttttcgt gtatctactt ttatgacttc cagttgaagg
     1261 gtcatattcc cgtcgccatg ggtaacggac aatgcgcttt cggagggaca attcaagccg
     1321 tagaccggat aagcggaaaa tgttttctgc tcggtctcga gcaaggtagc cgcgtcggaa
     1381 gtggataact tgtctccata gtagatgaat cttacctctc cgccgacagg tgcgtctagc
     1441 aataatgagg tattcctcgt ggaaatcaat acgtcttgtg cccataaact agtggtcaat
     1501 agggaggcgc aacataaata accgaattta ctcttaatgt tcattttatt agtaggtgtt
     1561 agatttaaat tcaggggcaa aagtaggaga gagccggtag gtttcctaat aggattttat
     1621 cagatactgt tacttttctg ctttaactaa aatttgtttc acgcagaaga accccgtgct
     1681 ttcattaatg aaaattccat attgtctaat tcgaaagaaa tcactaactt tgcggcaatt
     1741 ttttagaagc aagataaata catcgcgata tgagtaagaa atttaccgaa tattctaagt
     1801 ttgacttgtc gaacgtaaat aaagaggtgc tgaagaaatg gaaggatgga gacatcttcc
     1861 ataagagtct tgaaacaaga gagggacatc ctacattcgt attctacgag ggccctccat
     1921 ccgcaaacgg tatgccgggt attcaccatg ttatcgcccg ttcgattaag gatattttct
     1981 gccgctataa aaccatgaag ggattcttgg tgaatcgtaa ggcgggttgg gatacacacg
     2041 gtctgcctgt cgagttaggc gtggagaagg ctttgggcat cacgaaggaa gatatcggta
     2101 agaagatttc tgtcgctgag tataacgccg cttgccgtaa ggacgtgatg aagttcacga
     2161 aagagtggga ggatctgacg cagaagatgg gttattgggt ggatatggag aatccgtata
     2221 tcacgtatga taaccgctat atcgagacct tgtggtatct attgaaagag ctttataaga
     2281 aaggtctttt atataaaggc tatacgatcc aaccgtattc gcccgccgcg ggtacgggct
     2341 tgagcacgca cgagttgaac caaccgggtt gttaccgtga cgtgaaggat acgacttgta
     2401 cggcacagtt ccatatattg gacccgaaac cggagatggc acaattcggc gatccttatt
     2461 tcttggcatg gacaacgact ccttggacgt tgccttccaa tacggcgctt tgcgtaggcc
     2521 cgaatattac ttatctggct gtacagactt ataatcctta cacgggtatc ccgatgactg
     2581 ctgttatagc gaaagattta ttgtctgctt atttcaatcc gaaagctgcg gagctttctt
     2641 tgtctgatta taaaccgggt gacaagctgg ttcctttcag cgtagtaggt gagtggaagg
     2701 gttccgagtt ggccggtatg aaatatgagc aattgatccc atgggtaaat ccgggtgaag
     2761 gtgcattccg tgtgatcacg ggtgatttcg ttacgacaga ggatggtacg ggtatcgtac
     2821 atatcgcacc gacgtttggt gcggacgata accgtgtggc gaaaacattc ggggttcctc
     2881 ctttgatgat gcaggataag gatggaaata tgcgccctat ggtggatatg accggtaagt
     2941 tctataagct ggaagacttg gctccggagt ttgtacaaaa ttgtatgaac gcctctgatt
     3001 atgatccatg gcaaggaaaa ttcgtgaaga acgcttacga tgatacgaag acggataaag
     3061 atgagacgtt agatatagag atctgcatga tgctgaaggc ccagaaccgg gtgttcaaga
     3121 tcgagaagca tgtccacaat tacccgcatt gctggcgtac tgataagccg gtattgtatt
     3181 atccgctgga tagctggttt atccgcacaa ccgcttgccg tgagcgcatg atcgagttga
     3241 acaatacgat caactggaaa ccgcagagca cgggtacggg acgtttcggc aaatggctgg
     3301 agaacttgca agactggaac ttgagccgta gccgttattg gggtactccg ttaccgatct
     3361 ggcgtacgga agatggtagc gaggagaagt gtatcggttc cgtggtagag ttgtttggcg
     3421 agatcgagaa atcggtgaag gccggcttta tggagtctaa cccttacaag gacttcgctc
     3481 cgggagatta tacgaaggag aattatgaga agatcgattt gcaccgtccg tatgtggatg
     3541 atattatctt ggtttccgct tctggtaagc cgatgaagcg tgagacagac ttgatcgacg
     3601 tatggttcga ttccggcgct atgccttatg cccagatcca ctatccgttc gagaacttgg
     3661 aggagttcga taatcgtcag atctatccgg ctgactttat cgctgagggt gttgaccaga
     3721 cacgcggttg gttctttacc ctgcacgctc tgggtaccat gatttttgat agcgtggctt
     3781 acaaggctgt cgtgtctaac ggtctggtat tggataagaa cggaaacaag atgtctaaac
     3841 gcttgggcaa cgctgttgat ccattctcta cgatcgagaa gtatggttcg gacccgttgc
     3901 gttggtacat gatcacgaac gcttctccat gggataatat taagtttgat atcgatggta
     3961 tcgaggaagt tcgccgtaag ttctttggta cattatataa tacgtattca ttcttcgctt
     4021 tgtacgcgaa cgtggatggc ttcgactact ccgatccgga tgtggaatgg agcaagcgtc
     4081 cggagattga ccgttggatc ctttctctgt tgaacagctt ggtgaaggat gtggatggct
     4141 acttggaggc ttacgagccg actcgtgccg gacgtgctat ctctgatttc gtaaatgata
     4201 acttgagtaa ctggtatgtg cgtttgaacc gccgccgttt ctggggtggt ggtatgacgg
     4261 aggataagtt atccgcttac cagactttat atacttgctt ggagacagtg gctaagttga
     4321 tggctccgat cgctccgttc tatgccgatc agttattctt agacttggtc gctgttacgg
     4381 gacgtgagaa cgttgagtcc gtacacttgt ccgatttccc ggtttacgac gagtctaaga
     4441 tcgacaagaa tttggaagag cgtatgcaaa tggctcaaga tgtttcttct atggtattgg
     4501 ctcttcgccg caaggtgaat atcaaggttc gccagccgtt gcatacggta atgattccgg
     4561 ttgtagacgc tcatcaacaa gagagtatcg aggctgttaa gaacctgatc ttgaacgagg
     4621 tgaacgtgaa ggagctgaag ttcgtggata atacggcagg tatcttggtg aagaagatca
     4681 aaccggactt taagaagttg ggcccgcgct acggaaagat catgaaggcg ttggccgcca
     4741 cgattcaatc gatgagccaa gaagatatca acgctttcga gaaagccgga acgtttacct
     4801 tgatggtaga tggacaggag gccgttttgg agcgtacaga tgtagagatc atctctgagg
     4861 atatcccggg ttggttggtc gctaatgaag gtcgcttgac agtcgctttg gatattaccg
     4921 taaccgagga tttgcgtaag gaggggctgg cccgtgagtt ggtgaatcgt atccagaact
     4981 tgcgtaagag cagcggtttc gatataacgg ataagatcca tgtatccatt ctttcttgcg
     5041 aggagatgga tgaggcgatc tatgattata aggattatat cgctaaccaa gtattggcgg
     5101 aatctatcga aatcatggat aatgcgatca gcgacgctac ggaactcgat ttcgaggact
     5161 ttaaattgtc cgtaaagatc gagaaagctt aaaaatagaa tagcatttct tgcggaagaa
     5221 ttaggaatga aatataggaa aatcgataat tatattatct ttgcatgcaa agaagaaata
     5281 atatgatttt atattcattc ttaattcttc tttttgattg atatttgaac gattgttgaa
     5341 cctaaatttt tttagaacca tggcagagaa gacaagatat tcagacgctg agctcgagga
     5401 gttccgcgct attatattag agaaactgga aatcgcgaag agggattacg agcttttgcg
     5461 atcaggggtt acgaattccg acggtaacga cgtggctgat acgtctccta cattcaaggt
     5521 gctggaggaa ggcgcttcta cgttatcgaa ggaagaggcg ggccgtttgg cgcaacgcca
     5581 gatgaaattc atccagaatt tacaggccgc tttgatccgt atcgagaata agacctacgg
     5641 tatttgccgg gagactggta aattgatccc gaaagaaagg ctacgtgctg tgcctcatgc
     5701 gactttaagt atcgaagcaa aacaaggagg tgcaaagtaa atgagatatt ctaaaggttg
     5761 gggagcagtg ttaatcataa tactgctcct tcttcttgac caagtgctga aaatatggat
     5821 taagacccac atgcagttgc atgagagtat agagataact ccgtggtttt atctctattt
     5881 tactgagaat ccgggtatgg cattcggtat agaggtgatt gggaaattat tcctttccgt
     5941 attccgtatc gtggctgtat tgtttatcgg atattatttg tataagctgg ttaaagaaaa
     6001 ttataaattc ggttttattg cctgtatatc tttggttttt gcgggggcgg tgggtaatat
     6061 aatcgactcg atattctatg gcgtgatctt cgaccatagt ttcgggcaac tcgctacttt
     6121 tatgccggag ggaggtggtt atgcctcttg gctgcatggt aaggtggtgg atatgttcta
     6181 tttcccattg atagagaccg tattcccgga ttgggttccg atctggggtg gacaggagtt
     6241 cgttttcttc cgtccgatct ttaatttggc ggactcggcg atttgcgtgg gagttttcct
     6301 tttgttaata ttttatcggc atactttgtc ggctagcctt tcgaaagaag agaaataaat
     6361 gcggagaaaa ttacggatat atggtatggc tttattagcc acgacgttgc tggcggcatg
     6421 tagtaaggtt ccggatggta ttctgtcgga gaaaaagatg cagggtgtct tgacggatat
     6481 gttgctggct gaggccatgg taaatgtgga ttataatact tataaatccg ataccatgaa
     6541 gcttgccttg tatgagtctg tattccgtaa gcatgatatt acacaggcgg tgtatgatag
     6601 ctcgttggtg tggtacggcc gtaacttgga tatttatatg gaggtctaca accgggtctt
     6661 ggccgatctt aataaacgga tcaataactt aggggatgtg caggcggacg ctgcgccggt
     6721 atcgaaccgg gattctgtgg atatttggcc tcgccgttct tatctggtct tgtctcctac
     6781 ctctgtattt aatggggtga ctttcgatat acgtccggaa acgaattatt cctcgggcag
     6841 tagtttcgtg ctgggcatgc gtgtctgggg attgaataac aaaatggctt ataagccgga
     6901 ggtacgttta agcgcagacc aaggtgatac gaccttgacg gtgaatagta agatcacgaa
     6961 agatggatat cacgagacga tcttgaagac tataccaact aagaaagtaa agcgtgtgtt
     7021 tggatatatc cgtatggata atatggatac gacttattat aaggtgtata tagatagctt
     7081 aagcttgatg aaatataact atggtaagga gcttgccgaa ttacctaagg attctattaa
     7141 gtaatctctc tatttgttta ttatacttat gagaagaatt gccgctcatt acgtttggtg
     7201 taagcaggtt tatcgtatgc attatatcga actggatgat aatggtgcgt ttcatggtgt
     7261 ttacccgttg aatgaggaga tagctggaac cgctttttat gatggagtgc tggtgccggt
     7321 tctttcctcg gaaccggcga ttggttttaa gcaggtgatg ggatcttggc cggcgttaac
     7381 cgaaaagatt acgccgggtt gttcagtcca tatatatcgt ttaagcggga ttcccttggc
     7441 gtctgcgaaa ctcggcacag accacagctg tagcgatggc cacattgaga gactctgagg
     7501 tgtctcttcc ttccggatag ttcgggatat ataatttttc gtttacaaaa gcctctatgg
     7561 cgggacgtat tccatttcct tcattaccca ttatcaagat accgtttccg gataaggttt
     7621 tctcatataa gttttctccg ccaaggaagg tgccgtataa aggtatggct tgggctgatt
     7681 gggcctgtaa gaacgtttcc agatcggtgt aatgtatttt tacgtgggcg agcgcaccca
     7741 tagtggcttg tacggttttt ggactgaaaa catcggcggt atctttgctg catacgatat
     7801 gggaaatacc gaaccagtcc gctaaccgga tgatcgtacc taagttgccc ggatcttgga
     7861 ttccgtctaa tgcgagaaca agctcctttt ccggcgttat ttccgttata tcccaattgg
     7921 ggcgtttaaa gatcgcgagt acatcttggg gatttttcag gaagctggct ttacgaatat
     7981 catcttcttc cgctaccaat aactccttgg ccggaatatc gccttgtgta gccatccaag
     8041 atggcttggc tattaataac tcacattcaa aggccggtaa catatcggct accaatttat
     8101 ttccttcggc tacaaaaaca ttattttcat tccggaattt ctttaattcc agagaacgga
     8161 tgtatttgac tttggtcttg cttagcatct tagttctttt tacaaaacaa aagtacggta
     8221 aattctttaa attccagtac attcgcgatc gtaaaaagct tggaatgatg aatcgatctc
     8281 tacgtatatg ctattttatc tgtatcgtac tactgctagc ctcttgtagt acgaccaagt
     8341 ttgtgccgga tggggaatat ttgctggata aggtggagat cgtgtcggat aacaaggatt
     8401 ataagtctgc ggatttaaaa tcttatctta agcagcaacc aaacttcaag gtgtttggtc
     8461 tgatgaagtg gcagttgttt gtctatgatt ggtctggtaa gaatgagaag aaatggatca
     8521 ataaacagtt ac
//
LOCUS       DBMDTB010000133         8504 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_2270_length_8504_cov_9.166250, whole genome shotgun sequence.
ACCESSION   DBMDTB010000133 DBMDTB010000000
VERSION     DBMDTB010000133.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 8504)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 8504)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8504
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2270_length_8504_cov_9.166250"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..186
                     /locus_tag="ACZPB4_15295"
     CDS             <1..186
                     /locus_tag="ACZPB4_15295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018668261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HIR1099619.1"
                     /translation="VLRSLVTDGLVNRKIYPTVPPKVEYYVSEFGETLIPYLEQLKQW
                     GQENFETIMENRRKNKY"
     gene            complement(415..771)
                     /locus_tag="ACZPB4_15300"
     CDS             complement(415..771)
                     /locus_tag="ACZPB4_15300"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099620.1"
                     /translation="MDEAVFIAQYTFLATPAVIEEESRILGKIARRLRCEYVIRFEDD
                     GKFYFLLETRSGYEEHFARCGWYIVSQTDFNSRLTIGMGLYESGNLAGFMYRLDSGSC
                     IRAIQENRHRAAWIIN"
     gene            1014..1307
                     /locus_tag="ACZPB4_15305"
     CDS             1014..1307
                     /locus_tag="ACZPB4_15305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010992672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIR1099621.1"
                     /translation="MEIVSIERKTFEEMKERFGCFSQHVRALCARYRPPEKMNWMDGA
                     DVCEKLGISKRTLQTYRDRGLLPYSQINHKIYYRTEDVESFVEAMSREMTEDE"
     gene            1309..1626
                     /locus_tag="ACZPB4_15310"
     CDS             1309..1626
                     /locus_tag="ACZPB4_15310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIR1099622.1"
                     /translation="MEVITRDTEEVRAYFEALEEGMRYLDTVTAHFRPAMNGEVYLTG
                     EDVCRLLHITPRTLQDYRTQRLIPYISLPGKTLYRQSDLLRMLEENYVDMRPKRKRGK
                     SPT"
     gene            complement(1720..3015)
                     /locus_tag="ACZPB4_15315"
     CDS             complement(1720..3015)
                     /locus_tag="ACZPB4_15315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009041185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HIR1099623.1"
                     /translation="METKRSTFATSFYIKRSAVRTRDGKAPIMVKISVDGDDKAVGTK
                     LFVTPDLWENGKAKGKSAEANEINGQLKEVSARLTNHYHRILREEDFVTAEKLRNAFL
                     GVGVMENCILKDFGNMNREFGAMVEKGQRAKSTYNKYLAVYNHFKTFLWEKKKRTDMA
                     YKELTKEIITDFDKYLRVEKGLSANTLWIYTMPLLSLTDKAWRRGIVRTDPFGEYSLE
                     MQETDRGYLTEEELRTLANAVFVKKQTSLVRDMFLFGCFTGLSYIDIKTLTHDKIQRM
                     DFDGEEWIITRRTKTRVSSNVPLMEIAKELIERYRGLAGGDLVFPMPSNSACNTHLKQ
                     IAKACGIHKEIGFHLSRHTFATTVYLCNGGTIEALSKILGHKHISTTQIYAEVTNRMV
                     SSDFRAISGNLAAMQRSVLEKKDRKQDGKRVRRSLRETA"
     gene            3282..6344
                     /locus_tag="ACZPB4_15320"
     CDS             3282..6344
                     /locus_tag="ACZPB4_15320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SusC/RagA family TonB-linked outer membrane
                     protein"
                     /protein_id="HIR1099624.1"
                     /translation="MKKKSEGKTRKCLTLLGGRTSLLLCLSLMFQSSYAAEDSTVPEM
                     GNMEIHQIAQQSSTIKGVVKDQKGEPLIGVSIVVKGTTNGTASDFDGNFTLDVPDNST
                     LVFSFIGFKSQEVRYTGQKTLNIVLAEDSETLDEVVVVGYGSQKKGEITSSVTSVKAS
                     DFNKAPVVNPMQLVEGRVAGLTVSRGSTDPNGEVKVQMRGASSLKGSNEPLVIIDGMP
                     GNMTSLNAIAPEDIEAIDVLKDGSAAAIYGTRGNNGVIIVSTRRPQAGTTQVDYSGYI
                     MHEAVYKRPEILNGDEFVAYGKETNNANIRDFGGRDNHYDALLNKSNFTHVHNLTATG
                     GNGKTNYRASLNYKKNDGMIRNTSRETINGSIAVNHRAFDDKLQLSFNLANSFVKVDA
                     VSDDVDKVGDIPNYGILYQAIRINPTMPIYKEDGSFWETYSGYEDFNPVARIYQRTKK
                     KEFKNLLANFKAQYEIIPGLTAAAFFAMEKNDALTNDYSMREEYSQYKDGTNGRAKKE
                     YYQNTNRTTEWTANYNTSINGVHNITGLLGYSYQDFEYEQFSAENKNFLTDVFGTNNL
                     EAGGYLKDGKAEMKSKKETSKLIAFFARANYNYDGKYMASASIRREGSTKFGANNKWA
                     WFPSVSAGWMISREDFMESQEVFDVLKFRAGFGITGSLPTDPYMSLATYGTGAGAWNA
                     YTGSWLTATYGPNINPNPDLKWEKNESLNIGFDFGLLGGRLNGTIDWYSRTTRDLISS
                     YNAQQPSLIYNTITTNVGTMRNRGIELALNAEVVKTKDFSYTANFTFSYENNKLTSLS
                     NDVYKSSYEDQYDLPSPGNPGKAYRLQEGQPIASFFGYVCDGINPDGTWNLRDIDGKE
                     GLSDADRTFIGNGLPKFKAGLQNTFTYKNFDFSFFLRGMFDYDVLNEGAIYFGTTVNI
                     DQSGTNVYKDALKNKVTEQPLFSSYYLEKGNFLKIDNVTLGYTFNFKNNKYVRNLRIY
                     GNVTNLATITGYSGLTPDVNVTGLQAGIEKRGSYPTTRTFTFGVNFGF"
     gene            6374..7969
                     /locus_tag="ACZPB4_15325"
     CDS             6374..7969
                     /locus_tag="ACZPB4_15325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009016818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RagB/SusD family nutrient uptake outer membrane
                     protein"
                     /protein_id="HIR1099625.1"
                     /translation="MKALKNICAISLLLGATAFTSCTDLTEEIHSSVIAENYYNNAGE
                     VMAAMMRPWGHFCGTMQVAQSPWSCNELSSDCAAWPQKGRHGYDNGDWIRLHRHQWIP
                     TDGQVVDAWKKLFEGIGYANNFLTDTENIDFEALQVPMSKAQAQAEMRVYRAYCYWYV
                     MDMFGTAPICEKIGEINPSSKSRAELFAWIEKELNESIPSLSESKTETYGRVSKWGAY
                     ALLARLYLNAEIYTGQARWDDCIAACDELAKGGFALDKKWNDTFRADNDKRSTEIIWS
                     IVYDEVYAKGMGWYQRWLHYAHQTGWDLQSGPWNGLVTQPTFYDSFADNDLRKIEGFL
                     IGKQYPRKVDENGNYYYDTTAEPLKGSEEYNGQDLVFVNYIKSMTEGEENSGARSIKY
                     EIQPGTTGDMNNDWVMFRYSEVIYNKAEALMRKNGGKATQEVVDMINSVRQRSFKAED
                     WEKAKYTTATLTMDEFLAEKGREFAFEGIRRTDLVRFNKFVTTSWWDKTASNEPKRNI
                     FPIPQRQLDANANLSPNEANSLF"
     gene            8151..>8504
                     /locus_tag="ACZPB4_15330"
     CDS             8151..>8504
                     /locus_tag="ACZPB4_15330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 92 protein"
                     /protein_id="HIR1099626.1"
                     /translation="MINLKKSMCCLFLAASSTVAIAQTSVVDLVNPIIGTNGMGHTFP
                     GACVPFGLVQLSPDTDTIPHNVDGKYQPRSYEYCAGYQHKNSSIVGFSHTHFSGTGHS
                     DLGDILIMPTTGTLKL"
BASE COUNT         2337 a         1959 c         2127 g         2081 t
ORIGIN      
        1 gttttgcggt cattggtaac ggacggattg gtaaatagaa aaatatatcc cacagttcca
       61 cccaaagtgg aatattatgt atctgaattt ggagaaactt taatccctta tttagagcag
      121 ttgaaacaat gggggcaaga aaattttgaa acgataatgg aaaatagacg gaaaaataag
      181 tattgaaatt tattgcaagg tacaagtata tatctatata tagcttgcac cttgcaataa
      241 ccttagaatg tttattttca acgatttgca taatccaaaa ataatgcgga catctgaacc
      301 caagatgttg gcagacagac accggacaac agcagacagc ttttaaggac taaaagcgtg
      361 acggatgcaa agccaaaatt tcagaaaatg ctgatattta ggaataaata acgcttaatt
      421 tataatccaa gcggcacgat gcctgttctc ctgaatcgcc cggatacagc tgccggaatc
      481 gagcctgtac atgaagcccg ccaagttccc gctctcgtac aagcccatgc cgatggtcag
      541 gcggctgttg aagtcggtct ggctgacgat gtaccagccg caccgggcga aatgctcctc
      601 gtagccggaa cgggtctcca gcaggaaata gaacttgccg tcgtcctcga aacggatgac
      661 gtactcgcag cgcaggcggc gtgcgatctt gcccaagatg cggctctcct cctcgatgac
      721 cgcaggagtg gcaaggaagg tgtattgagc gataaagaca gcctcgtcca tagtgatgat
      781 gtttggtcgg ttacaaatat gcgaaatgtc cggcacacgg caagcggaaa gggcggaaaa
      841 tatgcggaag ggcgtgcgga tatgtagagc ttctccctgc ttttcaccgc ccggaacgtg
      901 acaaggctac aaacgtgaag caaaacgagg acaagcggta cggttttgat acacggacat
      961 atacagaccg gtatatttgc agggaagtat aacaataaaa acatatcggg acaatggaaa
     1021 tagtaagcat cgagagaaag accttcgagg agatgaagga acggttcggc tgcttttcgc
     1081 agcacgtgag ggcgctttgc gcccgctacc gcccgcccga aaagatgaac tggatggacg
     1141 gggcggacgt gtgcgagaaa ttaggcatca gcaagcggac attgcagacc taccgtgacc
     1201 gggggctgct gccgtacagc cagatcaacc acaagattta ctaccggacg gaggacgtgg
     1261 agtcgttcgt ggaagccatg agccgggaaa tgacggagga cgagtgagat ggaagtgatc
     1321 acaagggaca cggaagaggt acgggcgtac ttcgaggcac tggaggaagg catgaggtac
     1381 ctcgacacgg taacggcgca cttccgcccg gcgatgaacg gcgaggtcta tctcacgggc
     1441 gaggacgtgt gcaggctgct gcacatcacg ccgagaacgt tgcaggacta ccgcacgcaa
     1501 cggctgatcc cgtacatatc gctgccgggc aagacgctct accgccagtc ggatctgctg
     1561 cgtatgctgg aggagaacta cgtggacatg cgcccaaagc gcaaacgggg gaaaagtcca
     1621 acataaacgc acgggggtgt gcatcgggaa atgcagcaaa ggcagggaca ccgcatcgga
     1681 agttcctgcc tttgccgcat tctgcaccgg ggaaaggcgt caagccgttt cccggaggga
     1741 gcggcgcacc cgcttcccgt cctgtttcct gtccttcttc tccagcacgc tccgctgcat
     1801 ggcggcgagg ttgccggaga tcgcccggaa atcggagctt accatcctat tggtcacctc
     1861 ggcgtagatt tgggtcgtgg aaatgtgctt gtgcccgagt atcttggaga gcgcctcgat
     1921 ggtgccgccg ttgcagagat agacggtcgt ggcgaaggtg tggcggctca ggtggaagcc
     1981 gatctccttg tggatgccgc aggctttggc tatctgtttg aggtgggtgt tgcacgcgct
     2041 gttgctgggc atggggaaga caaggtcgcc cccggcaagc cccctgtacc tctctatcag
     2101 ctccttggca atctccatga gggggacgtt gctcgataca cgggtcttgg tgcgccgggt
     2161 gatgatccat tcctcgccgt cgaagtccat gcgctgtatc ttgtcatggg tgagcgtctt
     2221 tatgtcaatg tagctaagcc cggtgaaaca cccgaagagg aacatgtccc gcacgaggct
     2281 ggtctgtttc ttgacgaaca cggcgttagc caaggtgcgc agctcctcct ccgtgagata
     2341 gccccggtcg gtctcctgca tctcaaggct gtactcgccg aaggggtcgg tgcggacgat
     2401 tccacgccgc cacgccttgt cggtcaggct gagcaggggc atggtgtata tccagagggt
     2461 gttggcactc agccctttct ccacccgcag gtacttgtcg aaatcggtga tgatctcctt
     2521 ggtcagctcc ttgtaagcca tgtcggtgcg cttcttcttc tcccaaagga aggtcttgaa
     2581 atggttgtaa acagccagat acttgttgta ggtggacttg gctcgctgcc ctttctccac
     2641 catcgccccg aactcccggt tcatgttccc gaagtctttg aggatgcagt tctccatcac
     2701 gccgacaccg aggaaggcgt tgcgcagctt ctcggcggtg acgaaatcct cttcccggag
     2761 gatgcgatgg tagtggttgg tgagccgggc ggagacctcc ttcagttgcc cgtttatctc
     2821 gtttgcctcg gcggacttgc ctttcgcctt gccgttctcc cagaggtcgg gagtgacgaa
     2881 cagcttggtt cccaccgcct tgtcatctcc gtcaacggag attttcacca tgatgggggc
     2941 tttaccgtct cgggttctca ctgcggatct cttgatgtag aacgaggtcg caaacgtact
     3001 tctctttgtt tccataactc taaaattttc gtttctaaag gtagttactt atttcttacc
     3061 aagagctatg caaaacaagg caaagcaatg aaacagaact tgttatgcca tatatacccc
     3121 gtttcggaac cggtagctgt ttagtagccg aactttgtcc gaaaggggtg ttttcaggct
     3181 ttttatgccg aagcctgctt caacccgccc tgcatacaag atgctgacct gcatttattt
     3241 atgtagaact ttgcttttct ttgcgcctta tgccgatttt tatgaaaaaa aagagtgaag
     3301 gtaagacgag gaaatgcctg actttattag gtggacgaac ctctttgtta ctttgtttat
     3361 ctttaatgtt tcagtcctct tatgcggccg aagattctac tgttcctgaa atgggaaaca
     3421 tggagattca tcagatcgca cagcaaagtt caaccattaa aggtgtagta aaagaccaaa
     3481 agggtgaacc tctgattggc gttagtattg ttgtgaaagg aaccacgaac ggaacagctt
     3541 cggactttga cggaaatttc accttggatg tgccggataa cagcacattg gtattttcct
     3601 tcatcggctt caaatcccaa gaagttcgtt ataccgggca aaaaacattg aacatagtct
     3661 tagctgaaga ctctgagaca ctagacgagg tagtagtcgt aggttacggt tcccaaaaga
     3721 aaggtgagat cacctcatcc gttaccagcg tgaaagcatc cgactttaac aaggcaccgg
     3781 tagtgaaccc gatgcaattg gtggaaggac gtgtagctgg tctgactgta tcacgtggta
     3841 gcaccgaccc gaatggcgag gtaaaagtac agatgcgtgg tgcctcatct ctgaaaggta
     3901 gcaatgagcc tctcgttatt attgacggta tgccgggtaa tatgacttct ttgaacgcta
     3961 tcgcacccga ggatatcgag gcgatcgacg tattgaaaga cggttccgca gccgctatct
     4021 acggaacccg gggtaataac ggtgtgatca tcgtctccac gagacgtccg caagccggaa
     4081 ctactcaagt ggattactca ggatatatca tgcacgaggc ggtttataaa cggccggaaa
     4141 tcttaaatgg agacgagttc gtcgcttatg gcaaggaaac caacaacgcc aatatccgcg
     4201 actttggtgg acgggataac cattacgacg ctttattgaa taagagtaat ttcacccatg
     4261 tacacaactt gaccgctacc ggtggtaatg gtaagacaaa ctatcgcgct tctttaaatt
     4321 acaaaaagaa tgatggtatg atccgtaaca ccagccgtga aacgatcaat ggctctatcg
     4381 ccgtgaacca ccgtgcgttt gatgataaac tacagctttc tttcaatcta gcaaactctt
     4441 tcgtgaaagt ggacgcggtt tccgatgatg tggataaggt aggagatatc cctaattacg
     4501 gcatattata ccaggcgatc cgtatcaacc cgacgatgcc tatttataag gaagacggct
     4561 ccttctggga aacttacagc ggttacgaag atttcaaccc ggtagcccgc atataccagc
     4621 gtaccaagaa aaaggaattc aagaatttat tggcgaactt caaggctcaa tatgagatta
     4681 tccccggtct gacagccgcc gctttcttcg ctatggagaa gaacgacgca ttaactaacg
     4741 attatagtat gcgtgaggaa tatagccaat ataaagacgg tacaaacgga cgcgccaaaa
     4801 aagaatatta tcagaatacc aatcgtacta ctgaatggac agcaaactac aatacttcca
     4861 tcaacggcgt acacaatatt accggtttgc tgggatacag ttaccaagat tttgaatacg
     4921 agcaattcag cgccgagaac aagaacttct tgacggacgt attcggtacc aataacctag
     4981 aagccggcgg ttacctaaaa gatggtaagg ccgagatgaa gagtaaaaaa gagaccagca
     5041 aactgatcgc cttcttcgcc cgtgccaact ataattacga cggtaaatac atggccagcg
     5101 cctctatccg ccgtgaaggt tccacaaagt tcggagcgaa caacaaatgg gcttggttcc
     5161 cctctgtcag cgcaggctgg atgatctctc gtgaggactt catggagagc caagaagtat
     5221 tcgacgtatt gaaattccgt gccggtttcg gtatcacggg tagtctacct accgatccat
     5281 atatgtctct cgctacctac ggcacaggtg ctggagcttg gaacgcttac accggttcat
     5341 ggctaaccgc cacttacggt ccgaatatca acccgaatcc ggatttgaaa tgggagaaga
     5401 atgagtcctt gaacatcggt ttcgacttcg gcttgctagg tggacgccta aatggtacga
     5461 tcgattggta tagtcgtacg actcgcgact tgatcagtag ctacaatgcc caacagccat
     5521 ccttgatcta caacacgatc accaccaacg taggcacgat gagaaataga ggtatagaat
     5581 tagcattaaa cgcagaggtc gtaaagacta aggatttctc ttacacggct aatttcacgt
     5641 tctcatacga gaataataaa ttgacatctt tgtctaacga cgtgtacaaa tcttcttacg
     5701 aggatcaata tgacctgccc tctccgggta acccgggcaa ggcttaccgc ctacaagaag
     5761 gacagccgat cgcgtcattc ttcggttatg tatgcgatgg tatcaatccg gacggaactt
     5821 ggaatcttcg cgacatagac ggaaaggaag gtctgtctga cgctgaccgt acctttatcg
     5881 gtaatggttt gccgaaattc aaggctggct tacagaacac atttacctat aagaactttg
     5941 acttcagctt cttcctgcgc ggtatgtttg attatgacgt attgaacgag ggtgctattt
     6001 atttcggaac gactgttaat attgatcagt ctggcacaaa cgtatacaag gatgccttga
     6061 agaacaaggt aacagagcaa ccattgttct cttcttatta tctagagaaa gggaacttct
     6121 tgaagatcga taacgtgaca ctaggttata cattcaactt caaaaataat aaatatgtgc
     6181 gcaacttacg tatttatggt aatgtcacca atcttgcgac tattacagga tactctggtt
     6241 taacccctga cgtaaacgta acaggactac aagcaggtat agagaagcgc ggatcttatc
     6301 ccaccacccg taccttcacg tttggcgtta attttggatt ctaattaagt aacaatagat
     6361 ttaagacaat acaatgaaag ctttaaaaaa tatatgcgca atttcattat tgctgggagc
     6421 taccgcattt acctcttgta cggacctgac agaggaaata catagctcgg taatcgctga
     6481 gaattattac aacaatgcag gcgaggtaat ggccgccatg atgcgtccat ggggacactt
     6541 ctgtggaact atgcaagtag cccaatcgcc ttggtcatgt aacgagttat cttccgactg
     6601 tgccgcatgg cctcaaaaag gtcgtcacgg ctatgacaat ggagactgga ttcgcttaca
     6661 ccgccatcaa tggattccta cggatggtca agtagtggat gcttggaaaa aattatttga
     6721 aggtatcgga tatgctaaca acttccttac agatacagag aatatagatt ttgaagcact
     6781 ccaagttcca atgtctaaag cacaagcaca agcggagatg cgtgtatatc gcgcttactg
     6841 ttattggtat gtgatggata tgttcggtac ggctccaatt tgcgagaaaa tcggtgaaat
     6901 caatccttcc tccaaatctc gcgcagagtt attcgcttgg atcgaaaaag agttaaacga
     6961 gagtattcct tctttgtcag agagtaaaac agagacctac ggacgtgtat ccaaatgggg
     7021 ggcttacgca ttattggctc gtctctattt gaatgcggaa atttatactg gacaagcacg
     7081 ctgggatgat tgtatcgcag cttgcgatga attagctaag ggaggtttcg cattggataa
     7141 gaagtggaac gacactttcc gtgcggataa cgacaagcga tctaccgaga ttatctggtc
     7201 aatcgtgtat gatgaagtat atgccaaagg aatgggttgg tatcaacgtt ggttgcatta
     7261 cgcacaccaa actggctggg atttgcaatc cggtccttgg aacggcttgg tgacacaacc
     7321 gaccttttat gactcattcg ctgacaacga cttgagaaaa attgagggtt tcttgatcgg
     7381 taagcaatat cctcgcaaag tagatgaaaa cggtaattac tactacgaca cgaccgcaga
     7441 gcctttgaaa ggttcagagg agtacaatgg gcaggatttg gtattcgtaa actacattaa
     7501 gtccatgacc gagggcgaag aaaacagcgg cgctcgctct atcaagtatg aaatccaacc
     7561 gggtactacc ggcgatatga acaacgactg ggtgatgttc cgttattccg aggttatcta
     7621 taacaaagcg gaggccttga tgcgtaagaa cggaggcaaa gcaacgcaag aagtggtaga
     7681 tatgatcaac agcgttcgtc aacgttcttt caaggcagag gattgggaga aagcgaaata
     7741 tacgaccgct acattgacaa tggatgagtt cttagccgaa aaaggtagag agtttgcttt
     7801 cgaaggaatc cgccgtacag acttggttcg ttttaacaag ttcgtaacca cttcttggtg
     7861 ggacaagact gcatccaacg aaccaaagcg taatatcttc cctattccgc aaagacaatt
     7921 ggatgctaac gcaaacttat ctccgaacga ggctaactca ttgttctaaa tatcaactaa
     7981 gtatagtaga aatccattat taacaaatta gcacttgaca atgatagagg actactatac
     8041 ttattgatct gaaaatataa aaggttacct ttgtcactat caaaggttat ccttggaact
     8101 atcaaaggtg accttttatg tttcatcctt ttctaactaa ttgatacgac atgataaatc
     8161 tcaagaaatc gatgtgttgc ctctttctgg cagccagctc aacagtagcg atcgcacaga
     8221 ccagtgtagt tgatcttgta aacccgatca tcgggacgaa tggaatggga catacgttcc
     8281 cgggtgcttg cgtacccttc ggactcgtac aactcagtcc ggatacggat accataccac
     8341 acaacgtaga tggtaaatac caacctcgct cctacgagta ttgtgcgggt tatcaacata
     8401 aaaacagtag catcgtaggt ttcagccaca cccacttcag cggtaccggc cactccgacc
     8461 tcggggatat cttgattatg cctaccaccg gaacgttgaa gcta
//
LOCUS       DBMDTB010000134         8395 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_2303_length_8395_cov_9.552930, whole genome shotgun sequence.
ACCESSION   DBMDTB010000134 DBMDTB010000000
VERSION     DBMDTB010000134.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 8395)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 8395)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8395
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2303_length_8395_cov_9.552930"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..3098)
                     /locus_tag="ACZPB4_15335"
     CDS             complement(<1..3098)
                     /locus_tag="ACZPB4_15335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SusC/RagA family TonB-linked outer membrane
                     protein"
                     /protein_id="HIR1099627.1"
                     /translation="MQIKIYISFLITALFLCVPHTRAQEIEVPITLNEHGTQLRDVLR
                     KIEQQSPYLFLYNETQLDMKQKINEKITSPDIRKILDRLCGPIGIRYEIMDVQILLMP
                     KIDTGKPKPYPVPVTGYITDEKGSPMEFVSVIDLLSGKGGLTNEEGYFRFFTDKDSCR
                     LQISHLAYKPELRTVGPDNRHLQIQLIPAVFNLDEVVAIGYGTLARKELTSAVGYVSS
                     ERFLSGKVNNPIQGIKGLIAGMSISGSSLSDINSIPDIQIRGAGSILAGNKPLVVVDG
                     VPGVSLNSLSLAEIASISVLKDGSSAAIYGSNGANGVILITTKSGKSSDKLQANYQTY
                     LAAAHEYNRPRVLSPEAFVAAGRDADLGYHTDWQAALIRSCPLEQNHDLSIQNGWKSG
                     AFRISMNYRDGQGLDIVSSRREYALRTHISQNLLSGYLELTVSLAYKKQHLRLGNHTA
                     FQQAMLANPTAPIYTDEEETEYLYPSGFERDNPVASLKEENRQQENQFMTGSLTARIN
                     WSKPFYSTIMLAENREESEENVYWTSRAKESVDNNRKGRADRTSSKYVNRTLDWTNHY
                     DKAWDQHTVKAMIGYSFQRWDHSGMNAGNADFPTDFFTWNNIGTGSYLTDGKATLSSF
                     KNSSKLISVFARFNYSYRDLLMLSASFRREGSSKFGANHKWGNFPALSGGIRLSELPA
                     FQTEWLDDLKFRVGYGVSGRHNFSPYQSLETYAGAGKVMVDGKWIQVFGPSNNPNPDL
                     RWEKSLHTNIGAEAILLNSRLMLSLNLFKRTTKDLLFVYNAIKPPMIHDNITTNVGTI
                     DSKGLEWEMNWLPVRTKNFQYSASLTGSLLSSTLKSLSNNQFKLGYTYLYDLPTPGLP
                     GPAIRLEEGKPIGSFFGWRYAGTDAEGNILVWSKDGRKIPTTERTEEDKNFIGNGVPK
                     VQLSFSHTFTWKNFDLRLFFTSWLGYDLLNLKQMYYGLQNVPVTNLLEDAYTRNDAIK
                     GDKIYCDYFLENGNFLKLEELTLGYKIPLPDNKWIQSLRCYFSVNNVFTLTGYTGGDP
                     AN"
     gene            complement(3115..4863)
                     /locus_tag="ACZPB4_15340"
     CDS             complement(3115..4863)
                     /locus_tag="ACZPB4_15340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RagB/SusD family nutrient uptake outer membrane
                     protein"
                     /protein_id="HIR1099628.1"
                     /translation="MKRYAPLLLTFLFLPLLFSCFNLEEDLYDQLEKEDYYADYESLM
                     ASVFRPYEHAKWAETNFSFWLQELSADQLVITQKREHWEDGGVWRMIHQHTWDTYEKN
                     SEQMWNACYGGIGYCNNTLADIQELSYDNFGLPESDKRQHIAELTALRAYFQLLLLDA
                     FRIPAISLTTEEEVGSATPQENFHFIEESLLNAIPDLPKAPSKNYEGRITQGAAAVLL
                     MRLYFNASWYINIPMWEQTGALCERIINGEFGTYSLTSEWTDLWNAGNQDCPELIWSY
                     PQSRQVGYDDFYYLFFMHYQAPERFGCGKDLPAAYNGCHLSPSYDPSGKPYPYTLGRT
                     FSKFPDTDLRKKNFKVLSQGIYEGLFLFGPQQIYNSDQLQYGAEEWGNYPLIFIDQVA
                     RYSDHLSDTEKKALTDKQLSSDTPWIIRDKRFTSLASNIKTGEENTGIRIVKYPLYPS
                     GDVGLMANNLVVLRLTEVYYTLAEVSFRLGNPAKAEAILNQIRKRYYAPEDWEQVRYP
                     EDGSVLTAQELLDEWGREFLAEKRRRTDLNRFGLFTTGIWWDKQPSDSYRQFYPIPAR
                     AISANPLLKRSEGYIY"
     gene            complement(4860..5861)
                     /locus_tag="ACZPB4_15345"
     CDS             complement(4860..5861)
                     /locus_tag="ACZPB4_15345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecR family protein"
                     /protein_id="HIR1099629.1"
                     /translation="MENKRFEHIITRYLKGKATPEEEAELLQAIHASKEWEAAFRKRT
                     AEWNPLEETEADPETDRKWNRIASIITPSESQSQTEEAPVISLVSTSSRRIWFSIAAV
                     VLLLLVSGVTVYFLNQGGKAGTGNAEWQTIIAAQEDRSILLPDGSSVYLRENSELSYP
                     EVFASSIREVKIKGEAFFEVTPNSEQPFIVDASGLSVKVLGTSFSVQTSDQGNEISVI
                     LVEGKVSLNNAHEKELVQLHPNQKADYFVNDEHYTVTEVDSERLTSWRKGIIFYDNAS
                     LDEIVRLIEQTYKVSLMYTRPENDDQRFSGAFLKTQKLETVLQQTNKLTGTNLILIQ"
     gene            complement(5885..6496)
                     /locus_tag="ACZPB4_15350"
     CDS             complement(5885..6496)
                     /locus_tag="ACZPB4_15350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma-70 factor"
                     /protein_id="HIR1099630.1"
                     /translation="MCEQLYLTDDRLLFDKIRGGNAKAFEYAFRKFSPRLEAFAQKYT
                     NDTNEAEDIVQDVFLKLWERRELLDNISLTSFLFMMVRNSCLNYLKHRQIADTVQQRI
                     PDTETAERLYAADFVPDPSSLLIQKELSDSIDQIMEELPPKCKEAFVLSRLNGLKNRE
                     IAEHMAITEKVVEKHITRALKRFRDGLRRYALLLGTLLSLWKW"
     gene            6710..8395
                     /locus_tag="ACZPB4_15355"
                     /pseudo
     CDS             6710..8395
                     /locus_tag="ACZPB4_15355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863703.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SusC/RagA family TonB-linked outer membrane
                     protein"
BASE COUNT         2111 a         1912 c         2041 g         2331 t
ORIGIN      
        1 atattagcgg gatcgcctcc ggtatatccg gtaagtgtaa atacattatt taccgagaaa
       61 tagcagcgta acgattgaat ccatttattg tctgggagag gaattttata tcccaaggtc
      121 aattcttcta atttcaggaa attaccgttc tccagaaaat aatcgcaata gatcttgtct
      181 cccttgatgg cgtcgttacg ggtataagcg tcttctaaaa gattggtaac cggtacgttt
      241 tgtagcccgt agtacatttg tttcagattc aacaggtcgt accccagcca agaggtgaaa
      301 aacaatcgta aatcaaaatt cttccaagta aacgtatggc tgaaagagag ctgcactttc
      361 ggtacgccgt tgccgataaa attcttgtct tcctcggttc gttccgtggt cgggatcttt
      421 ctcccgtctt tgctccatac caagatatta ccctcggcgt cggttccggc atagcgccaa
      481 ccgaaaaagg agccgattgg ctttccctcc tccaagcgga tagccgggcc gggtaatccg
      541 ggggtgggaa gatcatacag ataggtatag cctagcttga actgattgtt ggaaagactt
      601 ttcagcgtac tgctcaatag gctacccgtg aggcttgccg aatattgaaa gttcttggta
      661 cgcacgggca gccagttcat ttcccattcc aatcccttgg agtcgatagt acctacgttt
      721 gtcgtgatat tgtcatggat catgggaggc ttgattgcgt tgtagacaaa caggagatct
      781 tttgtcgtac gtttgaatag attcaaggag agcatgaggc gggagttaag taagatcgcc
      841 tcggcgccta tgttggtatg caggcttttt tcccagcgta aatccggatt ggggttattg
      901 ctaggtccga atacttgtat ccatttgcca tctaccatga ctttacccgc tccggcgtac
      961 gtctctagcg attggtaagg ggagaaatta tggcggcccg ataccccgta accaaccctg
     1021 aatttaagat cgtccaacca ttccgtttgg aaggcgggta actcgctcaa gcgtatacca
     1081 cccgaaaggg cagggaagtt gccccattta tgattcgccc cgaatttact ggaaccttcc
     1141 ctgcgaaacg aggcggaaag catcaataag tcccggtagg aataattaaa ccgggcaaag
     1201 acactaatca acttgctgga attcttgaac gagcttaaag tcgcttttcc atcggttaga
     1261 taagaaccgg tgcctatgtt gttccatgtg aagaagtcgg taggaaagtc ggcatttccg
     1321 gcgttcattc ccgaatgatc ccaacgttgg aatgaatagc ctatcatcgc tttgaccgtg
     1381 tgctggtccc acgctttatc gtaatgattc gtccagtcta gcgtccggtt tacatatttg
     1441 gaagaggtac gatccgctcg ccctttccgg ttattgtcta cggattcttt ggcccgtgag
     1501 gtccaataga cattttcctc actctcttcc cggttctcgg cgagcataat ggtggagtaa
     1561 aaaggtttgc tccagttgat ccgtgcggtt agcgagccgg tcataaactg gttctcttgt
     1621 tgccggtttt cctcttttag tgaggctacg ggattatccc gctcgaaacc ggaaggatag
     1681 agatactccg tctcctcctc atcggtatag atcggggcgg taggattggc tagcatcgcc
     1741 tgttggaaag ctgtatggtt acctaggcgc aaatgttgtt ttttgtaagc gagcgatacg
     1801 gttagctcca gatagccgga gaggaggttt tggctgatat gggtacgtaa ggcgtattcc
     1861 cggcgggagg atacaatgtc tagcccttgt ccgtccctgt aattcatgga gatacggaac
     1921 gccccgcttt tccatccgtt ttgaatggat aaatcatgat tttgttccaa ggggcaggag
     1981 cgtatcaaag cggcttgcca atccgtatgg taccctagat cagcgtctct cccggctgct
     2041 acaaaggctt cgggcgaaag gacacgaggt ctattatatt cgtgagcggc cgctaggtag
     2101 gtttggtaat tggcctgcaa cttatccgag cttttaccgc ttttggtcgt tatcaagatc
     2161 actccgttag ccccgttcga tccgtaaatg gcggcggaag atccgtcttt taataccgat
     2221 atggaggcga tttcggctag tgataaacta ttcaaggata ctccgggtac cccatctacc
     2281 acgactagcg gcttgtttcc ggccaaaata gacccggcgc cccgtatctg tatatccggt
     2341 atcgagttta tatcggacaa ggaagatccc gagatactca ttccggcgat caatcctttg
     2401 atgccttgga tgggattgtt gaccttcccg gataagaacc gttccgagga tacataaccc
     2461 acggctgatg tcagttcctt gcgtgccaag gttccgtagc cgatcgctac cacctcgtcc
     2521 aaattaaaga cggccggtat caattggatc tgtaaatgac ggttatcggg ccccaccgtc
     2581 cttagctccg gcttataggc cagatgggag atttgtagcc ggcacgaatc cttatccgta
     2641 aagaagcgga aatacccttc ctcattcgtt agtcctcctt taccggaaag aaggtcgatt
     2701 accgagacaa attccatggg agaccctttc tcatccgtga tataacccgt aaccgggact
     2761 ggatagggct tgggcttccc cgtatcgatc ttaggcatca acaagatttg tacgtccatg
     2821 atctcatagc gtatcccgat cggtccgcat agccggtcta gtattttacg gatatccggc
     2881 gaggttattt tctcattgat tttctgtttc atatccaact gagtctcgtt gtataggaaa
     2941 agataagggg attgttgctc tattttccgc aatacatccc ttaattgagt cccatgttca
     3001 ttcaaggtga tgggaacctc gatctcttgg gcccgtgtat gcgggacgca aaggaacaga
     3061 gccgttatta agaatgatat gtatatcttg atttgcatag ggtgaattaa acggttaata
     3121 gatatatcct tccgagcgtt tcaataaggg attggccgat atcgcccggg caggtatcgg
     3181 atagaactgg cgataactat cggagggttg cttatcccac cagataccgg tcgtgaatag
     3241 gccgaaccgg tttaaatcgg tacgtcttcg tttctccgct agaaattcac gtccccattc
     3301 atccaataat tcctgtgcgg taaggacgga gccatcttcc ggatagcgta cttgttccca
     3361 gtcttccggc gcatagtatc gtttgcgtat ctggttcaag atcgcctcgg ccttggctgg
     3421 attacccaga cgaaaggaaa cttccgccag cgtataataa acctctgtca gccgtaacac
     3481 taccagatta ttcgccatca gccccacgtc tccggatgga taaagcggat atttcacgat
     3541 acggatacct gtattctcct cgccggtctt gatattggat gcgagggagg tgaatctttt
     3601 atctcgtatg atccacggcg tatcggaaga taattgttta tctgtgagtg ctttcttttc
     3661 cgtatcggat agatggtcgg aataacgtgc tacttgatct atgaaaatga gggggtagtt
     3721 tccccattcc tcggcgccat actgaagctg gtcgctattg tatatctgtt ggggtccgaa
     3781 gaggaataat ccctcgtaaa tgccttgtga gagtaccttg aagttcttct tccggagatc
     3841 cgtatcagga aatttggaaa acgtgcgtcc taacgtataa gggtagggct tgccggatgg
     3901 atcgtaagag ggactgaggt gacaaccatt ataggccgcc ggcaaatcct tgccacagcc
     3961 gaatcgttcg ggcgcttggt agtgcataaa aaacagatag taaaaatcat cataccctac
     4021 ttgccgggac tggggataag accagattag ttccggacaa tcttgattgc ctgcgttcca
     4081 taaatcagtc cattccgagg tgagagagta agtgccgaac tctccgttga taatccgttc
     4141 gcaaagcgct ccggtctgtt cccacatcgg tatattgatg taccaagacg cgttaaaata
     4201 gagcctcatc aataatacgg ccgccgctcc ttgggtgata cgtccctcgt aattcttaga
     4261 gggtgccttg ggtaaatcgg ggatggcgtt taataagctc tcttctataa agtggaaatt
     4321 ttcttgtggg gtggctgaac cgacctcttc ctctgtcgtg agggagatcg cggggatgcg
     4381 gaacgcatcc agaagtaaaa gttggaaata agcccgtaaa gcggtaagct cggcgatatg
     4441 ctgccgcttg tcggactctg ggagtccgaa gttatcatat gataactctt ggatatccgc
     4501 caacgtattg ttacaatatc cgataccacc gtagcaagcg ttccacattt gctcgctgtt
     4561 tttctcgtac gtgtcccatg tatgttggtg gatcatacgc catacgcccc cgtcttccca
     4621 atgctctcgt ttttgggtga tcacgagctg atccgccgat aactcttgca gccagaaaga
     4681 gaaattagtc tccgcccatt tcgcgtgctc ataaggacgg aatacggagg ccattagaga
     4741 ttcataatcc gcataataat cctctttctc cagctggtcg tataggtctt cttccagatt
     4801 gaagcaggag aagagcaacg ggagaaaaag aaaggttaac agcagtggtg cgtatctctt
     4861 cattgaataa gaatcaagtt cgtacccgtg agtttattgg tttgttgtaa tacggtttct
     4921 aatttttgtg tctttagaaa agcgccggag aaacgttgat catcgttttc cggacgtgtg
     4981 tacatgagtg agaccttata ggtttgttcg atcaagcgta cgatttcatc tagggaagcg
     5041 ttatcataaa agatgatccc ttttctccac gaggtaagcc gttcactatc aacttccgtt
     5101 accgtataat gttcgtcatt cacgaaataa tcggcttttt ggttcggatg caactgtacc
     5161 aattctttct catgcgcgtt attcaggctc acctttcctt ctaccaagat cacggagatc
     5221 tcatttcctt gatcggaggt ctgtacgctg aaagaggttc ccagtacctt gaccgataag
     5281 ccggaagcat caactataaa aggctgctcg ctattgggag tgacctcaaa gaaggcttct
     5341 cctttgattt tgacctctcg tatggaagag gcgaagacct ccggatagct tagctcggaa
     5401 ttctctctca gataaacgga actaccatcg ggtaaaagga tcgaacgatc ctcttgcgca
     5461 gctataatcg tttgccattc ggcatttcct gttcccgctt ttccgccttg attcaagaaa
     5521 tagacggtaa ctccggatac aagcaatagt aagaccaccg ctgctatcga gaaccatatt
     5581 cttcgggaag aagttgagac caaagaaata accggtgcct cttcggtctg cgactgagat
     5641 tccgagggcg tgatgatcga agcgatccga ttccatttcc ggtccgtttc cggatcggct
     5701 tcagtctctt ccaaaggatt ccattcggca gttcgcttcc ggaaagcggc ctcccattcc
     5761 ttggaggcat ggatggcttg aagcaactcc gcttcttcct ccggggtcgc cttgcctttc
     5821 agataccgtg taattatatg ttcgaatcgt ttattctcca ttttcctgtt ttactaaatc
     5881 tgtattacca tttccaaaga ctaaggagcg ttcccagtaa taaggcataa cgccttaatc
     5941 catcccggaa tcgtttcaag gcacgagtga tgtgtttctc caccactttc tccgtaatag
     6001 ccatatgttc cgctatctcc cggtttttca agccattcag acggctgaga acgaacgctt
     6061 ccttgcattt gggcggtagt tcctccataa tctgatcgat cgagtcggac agttcctttt
     6121 ggatcagcaa ggaggaaggg tcgggtacga aatccgccgc gtataatcgc tcggcagtct
     6181 cggtatccgg tatccgttgc tgtaccgtat cggctatctg acggtgtttt aaatagttta
     6241 gacaactatt ccttaccatc atgaaaagaa aagaggtcag cgagatgtta tccagcaact
     6301 cccttctttc ccataatttc aagaatacat cctgtacgat atcctccgcc tcgtttgtat
     6361 cgttggtgta tttctgggca aatgcctcta aacggggaga gaacttgcga aaagcgtatt
     6421 cgaacgcctt tgcgttgccc cctctgatct tatcgaaaag aagacgatca tccgttagat
     6481 acaattgctc acacatacca ctttagataa aagattgagg caaatgtaac aaaagtattc
     6541 tattttatga tcaaatcaat ttattatata acaactaggc ccgcttttac ccgcccttta
     6601 ttcctgtaag attattttat gtccgagaag ggggggattc cccctcttgg ttgttttatc
     6661 aagcaaacga aataaataaa attaatttag taatcttaaa ttgtaaagca tgaaaaagca
     6721 tttcttctct ttgcgggaaa gaggtctgtt cctacttctt ttgggacttt ttctttcctt
     6781 tagcagttat gctcaagaca ttaccgtaaa aggtgtagtg aaagactcta aattcggcga
     6841 tccgattatt ggagctagtg tccttgtgaa aggaacaacg aatggtacga tttccgatat
     6901 ggacggaaat ttcacgttgg cagctccgaa agacgggact ctgaccatct cttatatcgg
     6961 ttataaatca caagagatcc cggtaaatgg acagcagaac ctgaatatca ttctggacga
     7021 ggatgtagag gcgttggacg aggtggtagt agtaggttac gctaccggta gcaagcgtac
     7081 gatctccggt gcggtagagc gtatcaagaa atgaggatat gaaccaaggt gtggtgaata
     7141 cgccgttgga atccttgaaa ggtaaggttg ccggtgtggt aatctccaag acgggtggcg
     7201 accctgcctc taagccttct atccgtgtac gtggtacgac ctctttgtcc ggtggtaatg
     7261 atcccttggt gattatcgat ggcgtattcg gagatttgag catgttggac gcgatcgctc
     7321 ccgccgacat cgagacgttc acgatcttga aggacgcttc cgagaccgct cagtacggct
     7381 cacgtggtgc cgccggtgta atcgtagtga ctacggtgaa aggtaagaac ggtatgaaga
     7441 cgttgagtta taacggcaac ttcggtatca gtaatgttta taagaacttg aagatgttat
     7501 ccgccgatga gttccgctct acggcgaagg cgttaggcat gactccgctg gatatgggag
     7561 gtaatacgaa tttcttcgac gagatcgagc aattgggtta tacgcagaac cataatatct
     7621 ctttcggcgc gggtaacgac gattcgaatt atcgtgcttc tgtaggcgtg atcgatcaac
     7681 agggtattat caagaatagc ggtatgaaga attatacggc taaactggac gcttcccaga
     7741 atatgttcaa caataagttg aaaatcgagt tcggtatgtt cggttccttg aaacaagtgg
     7801 attatacgaa cgattatgag aaaactttct attcggccgc cacttacaac ccaaccttcc
     7861 ctacgcataa gaatgaggat ggcaaatggg atgaggatcc ctacgcaaac gagatccaga
     7921 acccgctggg acgccttgag atacaggatc gtgagaagaa cgcttacgtg aacgtacacg
     7981 gtaaattgac ttggacgatt ctggacgggt tgaaactgag cgcattcggc tcttatacgt
     8041 ataacgtgaa ggagaacatg aagtatatcc cgaaagattt gaaggcgatt acgcaaactt
     8101 ccgacgctca tggttaccgt gcggataata agcagaatat cttgatgggt aatatccagt
     8161 tatcctataa taaggatttg aatgagaaac atcatatcga cgctttggcc ttggtagagg
     8221 gacaaaaata tcattatacg ggatttagcg ccggtgcccg tggctttgag acggattact
     8281 tcggttataa caacctgaaa gcgggtggta cggtgaaata cggagacgtg acttctttcc
     8341 aaaacgagaa tcgtctggcc tcattcatgg gtcgtttcaa ttatatgtat gacaa
//
LOCUS       DBMDTB010000135         8340 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_2325_length_8340_cov_11.126957, whole genome shotgun sequence.
ACCESSION   DBMDTB010000135 DBMDTB010000000
VERSION     DBMDTB010000135.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 8340)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 8340)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8340
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2325_length_8340_cov_11.126957"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..819
                     /locus_tag="ACZPB4_15360"
     CDS             <1..819
                     /locus_tag="ACZPB4_15360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005781094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PEP/pyruvate-binding domain-containing protein"
                     /protein_id="HIR1099631.1"
                     /translation="GSLKYIVSTYDPYDQIIRDGYYPGGRKILSFVNILQHDVFPLAD
                     TLDQILRIGQQEMGRPVEIEFAVNMDPSDHTRATFYLLQIRPIVDNKEIMDEDLSLVK
                     NEETILSSTSVLGHGIVGDVQDIIYVKTGAFNSSNNQLIAYEIEKMNRSFTDQEKGYV
                     LVGPGRWGSSDSWLGIPVKWPHISNARVIVECGLENYRVDPSQGTHFFQNLTSFGVGY
                     FTVNPFKGDGWFDEAFLNAQPAVEETEYLRHVRFDAPITIKMDGKKSLGVVLKP"
     gene            complement(900..1931)
                     /locus_tag="ACZPB4_15365"
     CDS             complement(900..1931)
                     /locus_tag="ACZPB4_15365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HIR1099632.1"
                     /translation="MKKTSFIYLLLLIALGLSSCQQEKTFKVLQFNIWQEGAVVKGGF
                     DAIADEIVRSNADFVTLSEVRNYHQTRFCDRIVEALQQRGQTYYSFYTEDSGLLSRYP
                     ITDSTTVYPLNDDRGSMYKAITHIGDTEVALYTAHLDYRNCAYYDARGYDGNTWDEEP
                     PVTNLDTLLWLNEQSVRDDAIACFLKEAKKDREAGRIVILGGDFNEPSHLDWTEATKD
                     MRDHQGLVVPWHVSVMLEKDGFKDTYREIFPNPVTHPGLTCPADCKDIALEKLVWSPK
                     ADDRDRIDFIHYAPFEGLTLTDVCIIGPKGDILRGQRETEETSDPIMTPLEIWPTDHK
                     AVLATFHLK"
     gene            complement(1947..2684)
                     /locus_tag="ACZPB4_15370"
     CDS             complement(1947..2684)
                     /locus_tag="ACZPB4_15370"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HIR1099633.1"
                     /translation="MKAMIFAAGTGSRLKPLTDHTPKALIPIGGKPMLEHVILKLKSS
                     GFDQIVINIHHLGNQIVDFLEANNNFGVRIEISDESDYLLDTGGGIKKATSLLCGNEP
                     FLIHNVDILSNVDLKKLYDTHVQTNPLATLLVSQRNTSRYLLFNKENRLCGWRNHETG
                     EVKSYYPYFDPDQHNEYAFSGIHVLSPKILELMEEWTGKFSIINFYLAICAKTDIRAY
                     MADNLKLLDIGKPETLAAAEEWLRQNI"
     gene            complement(2681..4111)
                     /locus_tag="ACZPB4_15375"
     CDS             complement(2681..4111)
                     /locus_tag="ACZPB4_15375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008017572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RapZ C-terminal domain-containing protein"
                     /protein_id="HIR1099634.1"
                     /translation="MITEELRKLYQSYTGSPAEEITELPSSGSNRRYFRIKGPETLIG
                     VSGTSIEENEAFIYMAKHFRGKGLPVPQVYASSDDHSFYIQEDLGDTLLFNAIEKGRK
                     SSVFDEEERRLLHKTITKLPDIQFLGSDGFDFSYCHPQAEFNQRSILWDLNYFKYCFL
                     KATGMEFQENRLEDDFLKMSDVLLRSSSATFLYRDFQSRNVMVKDGEPWFIDFQGGRK
                     GPVYYDVASFLWQAKAKYPEDLRNELLSDYITALRKYIPVDEAYFHSQLRHFVLFRTL
                     QVLGAYGFRGYFEKKPHFIQSVPFAIENLRQLLKNDYPEYPYLCSVLRELTGLKQFTD
                     DIQKHMLEVKVMSFAYKKGIPNDPSGNGGGFVFDCRAINNPGKYERYNHFTGLDEPVI
                     QFLEDDGEITNFLEHVYHIVDASVKRYMDRGFTNLMICFGCTGGQHRSVYSAQHLAEH
                     LNTKFGVKVHLVHREQNIEQLFNPTL"
     gene            complement(4293..5627)
                     /locus_tag="ACZPB4_15380"
     CDS             complement(4293..5627)
                     /locus_tag="ACZPB4_15380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010993399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HIR1099635.1"
                     /translation="MKASEVLDNLKRRFPNEPEYHQAVSEVLGTIEEAYNEHPEFEKS
                     NLIERLCIPDRIFSFRVTWMDDKGQIQTNMGYRIQHNNAIGPYKGGIRFHASVNQSIL
                     KFLAFEQTFKNSLTTLPMGGGKGGSDFSPRGKSNAEIMRFCQAFILELWRHIGPDTDV
                     PAGDIGVGGREVAYMYGMYKKLARENTGTFTGKGIEFGGSLIRPEATGYGNVYFLLQM
                     LKTRNIDIKDKVVCVSGSGNVAQYTVEKLISLGAKVVTMSDSDGYIYDPDGIDREKLD
                     YIMELKNLYRGRIREYAEQYGCKYVQGARPWGEKCDIAMPSATQNELNGDDAKTLLAN
                     GCFAVSEGANMPSTPEAIDAFLEAKILYAPGKAANAGGVSVSGLEMTQNAQKLSWSSE
                     EVDQKLQSIMESIHEQCVKYGKQEDGYVNYVKGANVAGFMKVAKAMMAQGIL"
     gene            complement(5793..5975)
                     /locus_tag="ACZPB4_15385"
     CDS             complement(5793..5975)
                     /locus_tag="ACZPB4_15385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099636.1"
                     /translation="MARRKITNSQAVCITLLWGVLCYMLLVYSETINFDVIFALVASA
                     IIVFVPIYKNFKHRDE"
     gene            complement(5989..6378)
                     /locus_tag="ACZPB4_15390"
     CDS             complement(5989..6378)
                     /locus_tag="ACZPB4_15390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012056180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative signal transducing protein"
                     /protein_id="HIR1099637.1"
                     /translation="MDKIVEIARFTYPADAQPLMALLRSEGIECYLRNELSSQIMAGY
                     VDVGGARVEILESDVPRAMKIMEEGGYDLPREDEQAEPVEQVAGFARHIPFLRKYPLE
                     KQIMILFVIIAVFLALVIYFGSLISSN"
     gene            6465..7397
                     /locus_tag="ACZPB4_15395"
     CDS             6465..7397
                     /locus_tag="ACZPB4_15395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009009 - site-specific recombinase
                     activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HIR1099638.1"
                     /translation="MKQYDLAEGMRMYIARLREQGRYSSAKSYQDALNSFLRFCGQEV
                     IPYTRIDREMLLRYQDYLRDRECSWNTVSTYMRRIRRVYGLAMENGEAPFSRYLFKGI
                     FMGVKSKQKKALPTESLRLLMTAPLDDSGLRKTQRALCLMFLFCGMAFVDFAHLKKSD
                     IRNGVLRYNRQKTGTPMLVEIQPVAKELLAALMTDTLRDSPYLFTFLSGTKTGEEAFR
                     EYTSALADFNSSLKELANACGVTEMVTSYSIRHSFATTLKEQGVPIEMISELLGHQSI
                     KTTQIYLKSFSLDKMSAVNKACFESIYNNVSKVG"
     gene            7904..>8340
                     /gene="nusG"
                     /locus_tag="ACZPB4_15400"
     CDS             7904..>8340
                     /gene="nusG"
                     /locus_tag="ACZPB4_15400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA];
                     GO_process: GO:0006354 - DNA-templated transcription
                     elongation [Evidence IEA];
                     GO_process: GO:0031564 - transcription antitermination
                     [Evidence IEA];
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HIR1099639.1"
                     /translation="MGHDLPPLPLRDVHTVRWYVLSLPACHKGPAKGLEKELDRRVRL
                     GGPTFDFFAPSFVEMHRREGRLVETHRPLLYNYVFIRSSVYEIFRLKRDFPLYNFLPS
                     VDGRGSYPFVSDREMENLRWVARSYSDELPVYVPEAGYLRKGDR"
BASE COUNT         2075 a         1882 c         1989 g         2394 t
ORIGIN      
        1 ggttccttga aatatattgt ctctacatac gatccgtacg atcagattat ccgtgacggt
       61 tattatccgg gcggtcgtaa gatcctttct ttcgtgaata tcctacagca tgatgtgttc
      121 ccgctggcgg atacgttgga tcagatctta cggatcgggc agcaggaaat gggccgtccg
      181 gtagagattg agttcgctgt caacatggac ccgtcggatc atacaagggc gactttctat
      241 ctgttgcaaa tccgtccgat cgtagataat aaagagatta tggacgagga tctgagcttg
      301 gtgaagaacg aggaaaccat cctttcttct accagtgttt tggggcatgg tatcgttggc
      361 gacgtacagg atattatcta tgtgaagacg ggcgctttta attcatccaa taatcagttg
      421 atcgcttatg agatcgagaa gatgaaccgt tcgtttaccg atcaggagaa aggatacgta
      481 ttagtcggcc ccggtcgatg ggggagcagc gactcttggt tgggtatccc ggtgaaatgg
      541 ccgcatatca gtaacgcacg ggtgatcgtg gaatgcggat tggagaatta tcgggtagac
      601 ccgagtcaag gtacccattt cttccagaac ctgacttcgt tcggagtggg ctattttacg
      661 gttaatccat ttaagggaga tggttggttc gatgaggcgt tcttgaatgc gcaacctgcc
      721 gtagaggaga cggaatatct tcgtcatgta cgttttgatg ctccgattac gattaagatg
      781 gatgggaaga aaagtcttgg cgtggtattg aaaccataaa aagatagcgt ttcaagagaa
      841 gatagttgtt tgtggatttg cgagacgagc cggtaagacg ggtctcgcga atccattttt
      901 tatttcaagt ggaaagtggc aagaactgct ttgtggtcgg taggccagat ttcaagggga
      961 gtcatgatcg ggtcggaggt ctcttccgtc tctctttgcc cacggaggat gtcacctttc
     1021 ggaccgatga tacatacatc tgtaagcgtt aatccctcga atggagcgta atggatgaaa
     1081 tcgatgcgat ctctatcgtc cgctttcggc gaccaaacca atttctctaa agcgatatcc
     1141 ttacagtctg ccgggcaggt aagtcccgga tgagttacag ggttcgggaa gatctcacgg
     1201 tacgtatctt tgaagccgtc tttctccagc atgacggata cgtgccaagg aacaaccaat
     1261 ccttggtggt ctctcatgtc tttggtcgcc tcggtccagt ccagatggga aggctcgtta
     1321 aagtctcctc cgaggataac gatccgtccg gcttcccgat cctttttcgc ctctttcagg
     1381 aagcaagcga tagcgtcgtc acggacagat tgctcgttca accataggag tgtgtccaga
     1441 ttggtgacag gaggttcctc gtcccatgta tttccgtcgt atccacgggc atcgtaataa
     1501 gcgcaattgc gataatccag atgggcggtg taaagagcta cctcggtatc gccgatgtgg
     1561 gtaatggcct tgtacatact acccctgtca tcgttcaagg gatagacggt cgtgctatcc
     1621 gtgatcgggt agcggcttaa cagaccggaa tcctcggtgt agaaagaata gtacgtttgt
     1681 cctctttgct gcaacgcttc cacgatccgg tcgcaaaaac gggtctgatg ataattacgt
     1741 acctcgctta acgtaacgaa atcggcgtta cttcttacga tctcgtcagc gatagcgtca
     1801 aagcctcctt ttacgacagc gccttcctgc cagatgttga attgaagaac cttgaaagtc
     1861 ttctcttgct ggcaagagct gaggcccagc gcgatcaaca agagtaagta gataaaacta
     1921 gtttttttca tgtgtgaaat attttgttag atgttttgtc gtagccattc ctcggcggcg
     1981 gccaaggttt ccggcttgcc gatatccaat agttttaggt tatccgccat ataagccctg
     2041 atatcggttt tggcgcaaat agccagatag aagttaatga tagagaactt tccggtccat
     2101 tcttccatca gctccaatat cttgggcgag agtacgtgga ttccgctaaa ggcgtactcg
     2161 ttgtgttgat ccgggtcaaa atagggatag taagatttta cctcgccggt ctcatgatta
     2221 cgccaaccac acagtctatt ctccttatta aataatagat aacgtgaggt attgcgctgg
     2281 ctgacgagta aggtagccaa cgggttcgtt tgtacatggg tatcgtatag tttcttgaga
     2341 tccacgttcg ataagatatc gacattatgt atcaagaaag gctcgttccc gcataaaaga
     2401 gaagtggcct tcttgattcc tcctcccgta tccagcagat aatcgctctc gtccgagatt
     2461 tcgatccgga caccgaagtt gttgttcgcc tccagaaaat ccacgatctg gttgcctaaa
     2521 tggtggatat tgatcacgat ctggtcgaaa ccggaggatt tcagtttcag tatgacgtgt
     2581 tctagcatcg gtttgccccc gataggtata agcgcttttg gcgtgtgatc ggttaacggc
     2641 ttcagtctgg aaccagtacc ggccgcgaaa atcatagctt tcataatgta gggttaaaga
     2701 gttgttctat attttgttct ctatgtacta aatgtacttt tactccgaac ttggtgttaa
     2761 gatgttccgc cagatgttgt gcggaataga ccgaacggtg ctgtcctccc gtacatccga
     2821 aacaaatcat caaattggtg aatccacgat ccatatatcg ttttaccgag gcgtctacga
     2881 tatggtagac atgctcgagg aaattcgtga tctccccgtc atcctccaag aactggatca
     2941 ctggctcatc caaaccggtg aaatggttgt aacgctcgta tttaccgggg ttatttatcg
     3001 cacggcaatc gaatacgaat ccacctccgt tcccgctagg gtcgttcggg attccttttt
     3061 tataggcgaa gctcatgacc tttacttcca gcatatgttt ctggatatca tccgtgaatt
     3121 gtttcaaccc ggtaagctca cgaaggacgg agcataaata gggatattcc ggatagtcat
     3181 tcttcaataa ctgccgcagg ttctcgatcg cgaacgggac gctttggatg aaatgaggct
     3241 ttttctcgaa atacccccgg aaaccataag cccccaatac ctgcaaggtc ctaaacagga
     3301 cgaaatggcg cagctggcta tggaagtaag cctcgtctac cgggatatat ttacgtaggg
     3361 ccgtgatata atccgatagt aattcattcc tcagatcctc cggatatttc gctttcgcct
     3421 gccaaaggaa ggaagccacg tcgtaataaa ccgggccttt tcgtccacct tgaaaatcaa
     3481 taaaccaagg ctctccgtcc tttaccataa cattgcgtga ctggaaatca cggtatagga
     3541 acgtggcgga tgaactgcgt aacaatacgt cgctcatctt caagaaatca tcttccagac
     3601 ggttttcttg aaactccatc ccggtagcct ttaagaaaca gtacttgaaa taattcaagt
     3661 cccaaaggat agaccgttgg ttgaactcgg cttgcggatg gcaatacgag aaatcgaaac
     3721 cgtcggaccc caagaactgg atgtcgggga gtttggtgat cgtcttgtgt aataaacggc
     3781 gttcctcctc gtcgaataca ctgcttttac ggcctttctc gatggcgttg aaaagaagcg
     3841 tatctcctaa atcctcttgg atataaaatg aatggtcgtc cgagctggca tatacttgcg
     3901 gtacgggtaa gcccttcccc cggaaatgtt ttgccatata gataaaagcc tcgttctcct
     3961 caatagaagt gccactaact ccaatcaacg tctcaggacc ttttatcctg aaataccggc
     4021 ggttagagcc ggatgacggt aactccgtta tttcctctgc cggtgatccg gtatatgatt
     4081 ggtatagctt cctaagttct tctgttatca tacttatcga tttacggcac taagataccg
     4141 ctttttaatt gaaaattaag aattgaaaat tgaaaattgg gacttcgtcg gaaataagaa
     4201 aggggaatag cctctcaaag cctatccccc tcgcttatat gatcatcaat ctctcctctc
     4261 taactaattt tcaattctca attttcaatt acctagagta ttccttgtgc catcatagcc
     4321 ttagctacct tcatgaagcc ggctacgttg gcgcctttca cgtagtttac gtaaccatcc
     4381 tcttgctttc cgtattttac gcattgctcg tggatacttt ccatgatact ctgaagtttc
     4441 tggtctactt cctcgctgct ccaacttaac ttctgtgcgt tctgagtcat ctcaagaccg
     4501 gaaacggata caccacctgc gttagcggcc ttacccggag cgtaaaggat cttggcctca
     4561 aggaatgcgt cgatagcttc cggcgtagaa ggcatgttag cgccttcgga tacggcgaag
     4621 caaccgttgg ccaataaagt cttggcatcg tcgccgttca actcattctg ggttgcgctc
     4681 ggcatagcga tgtcgcattt ctctccccaa ggacgagcgc cttgtacata tttgcatccg
     4741 tattgctccg cgtattcacg gatacggcca cgatacaagt tcttcaactc catgatataa
     4801 tccagtttct cacggtcgat gccatccgga tcatagatat aaccgtcgga atcagacatc
     4861 gtgacaactt tcgctccaag actgattaat ttctctaccg tatattgagc cacgtttccg
     4921 gaacctgata cacaaactac cttgtctttg atatcaatgt tgcgggtttt cagcatctgc
     4981 aacaagaaat atacgtttcc gtaacctgta gcttccggac ggatcaagga acctccgaac
     5041 tcgataccct tacccgtgaa tgtacccgta ttctcacgag ccaatttctt gtacattcca
     5101 tacatataag ccacctcacg tccgcctaca ccgatatcgc cggcgggaac atccgtgtcc
     5161 ggaccgatat ggcgccataa ctcaaggatg aaggcttggc agaaacgcat gatctcagcg
     5221 tttgactttc ctctcgggct aaagtcggaa cctcctttac caccacccat cggcaatgta
     5281 gtcagtgaat ttttaaacgt ttgctcaaaa gccaagaact taaggatcga ttggtttacg
     5341 gaagcgtgga aacggatacc gcctttgtac gggccgatag cgttgttgtg ctggatacgg
     5401 taacccatgt tcgtctggat ttgtccctta tcgtccatcc aagttacacg gaaagagaaa
     5461 atgcgatcgg ggatacaaag gcgctcgatc aagttgcttt tctcaaattc cggatgctcg
     5521 ttgtaagctt cctcgatagt ccctaaaacc tctgatactg cttgatgata ttccggttcg
     5581 ttcggaaatc ttcttttcaa gttgtctaaa acttcacttg ccttcatgac tgaattttat
     5641 atttagaatg ttataccatt ttgttatccg tacgccgttt gtttaacgac gtggcaaagg
     5701 taagctaatt tttgacacta gcaaataatt gaaagagaaa atgcgtaaaa aatatcattt
     5761 agatatatta agtttgaaaa aacgacgaaa tgttattcat ctctatgctt gaaattctta
     5821 tagatcggaa cgaacacaat gatagcggag gctacaaggg caaatatgac atcgaaattg
     5881 atcgtttcgc tgtatacaag cagcatgtag cataagacac cccatagtaa ggtgatacat
     5941 acggcttgac tatttgttat ctttctgcgt gccattgatt acatttgttt agtttgagga
     6001 aataagcgat ccgaagtaaa tcaccaaagc caaaaagaca gctatgatga cgaataggat
     6061 catgatttgt ttctctaagg gatattttcg tagaaaaggg atatgacgtg cgaatccggc
     6121 gacttgttct accggttccg cttgctcgtc ttcccggggc aggtcgtaac cgccttcctc
     6181 catgatcttc atggctcggg gaacgtcgct ttccagaatc tccacccgtg cgccgcctac
     6241 gtctacgtaa ccggccatga tctggctgct taactcattg cggagataac attctatccc
     6301 ttccgacctc aacagggcca tcagcggttg ggcatccgcc ggataggtga accgggctat
     6361 ttctacgatc ttgtccatgg tatttgtttt tctgcaaatg taagtagaca atcacgaatt
     6421 aaccgtgttt tttattgtaa tttacttttt ttatacgtga aaatatgaaa cagtatgatt
     6481 tagcggaggg tatgcggatg tatatagccc gattgagaga gcaaggacgt tattcgtccg
     6541 ccaagagtta tcaagatgcc ttgaattcat tcctgcgttt ttgtgggcag gaggtgattc
     6601 cttatacccg tatcgaccgg gaaatgcttt tgaggtatca agactatttg cgggaccggg
     6661 aatgctcgtg gaatacggtg tctacctata tgcgtaggat tcgccgtgtg tatgggttgg
     6721 cgatggagaa tggggaggct cctttttccc gttatttgtt caagggaatt ttcatgggag
     6781 tgaaaagcaa acagaagaag gcgttgccta cggaatcctt gcgtttgttg atgaccgctc
     6841 cgttggatga ttcggggctg cggaaaacac agcgggcatt gtgtttgatg ttcttgtttt
     6901 gcggtatggc gtttgtcgat ttcgctcatt tgaaaaagag tgatatccgg aatggtgtct
     6961 tgaggtataa ccgccagaag acgggtacgc cgatgttggt cgagatacag cctgtggcca
     7021 aggagttgtt ggctgcgtta atgaccgaca cgcttcggga ttctccttat ctattcactt
     7081 tcttgagtgg gacgaaaacg ggtgaagagg ccttccggga atatacctct gccttggctg
     7141 atttcaacag ttccttgaag gaactggcaa atgcctgtgg tgtgacggaa atggttacct
     7201 cgtactcaat ccgtcactct ttcgccacga ccttgaagga acagggtgta ccgatcgaga
     7261 tgatcagcga attgctggga caccaatcga tcaagacgac gcaaatctat ttgaagagct
     7321 tctctttgga taagatgtct gcggtgaaca aggcttgctt cgagagcata tataataatg
     7381 tatcaaaggt ggggtaggcg atcggctact tgggaagtag cgtaatcttc cacgccgcaa
     7441 atttagtaaa aaacaccgaa taacaaacaa tttttaggct ttgtgtaggc tttgtttgtt
     7501 ttctgaattt atctttcttc aatttttcgt ttctattcgt ggtgtatggg cacgacaatg
     7561 gagacgaaac gacctcatat ttcctgcatc atcacgtctc cccaaaaaat cgtacgaaca
     7621 tcgtgtagag acggggcgtg ccccgtctca tcccctcaaa tgggtatttt aattactgcc
     7681 agacagtggg agacggagca cgctccgtct ctacaactgg gtaataatca tttcctatct
     7741 tttacgctac ttcccaagta gccgatcttc cacgtcccga tagaagagat attgacatgg
     7801 tttctattgc tttaaaattt tcgggaatag aaaagaatat ttgatttaag tattagatta
     7861 tcagcgtatt aatagaatgt gctgatatgg cattgaagta tctatgggtc atgatcttcc
     7921 ccctttacca ttgcgtgatg tccacaccgt aagatggtat gtgttatctc ttcccgcttg
     7981 tcacaaaggt ccagccaagg gtttggagaa ggagttagat cgcagggtgc gtttgggcgg
     8041 gcctacgttc gattttttcg ccccctcttt cgtggagatg catcgccgtg aggggcgttt
     8101 ggtggagact caccgtccgt tgctctacaa ttatgtgttt atccgctctt ctgtgtatga
     8161 gatctttcgt ttgaaacgag attttccctt gtataatttc ctgcctagcg tggatggccg
     8221 tggctcatat ccttttgtct ccgatcgtga gatggaaaac ttgcgttggg tggcccgttc
     8281 ttactcggat gagcttccgg tgtatgtgcc ggaagcgggt tatttgcgta aaggtgaccg
//
LOCUS       DBMDTB010000136         8234 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_2357_length_8234_cov_12.943809, whole genome shotgun sequence.
ACCESSION   DBMDTB010000136 DBMDTB010000000
VERSION     DBMDTB010000136.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 8234)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 8234)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8234
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2357_length_8234_cov_12.943809"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            514..2574
                     /locus_tag="ACZPB4_15405"
     CDS             514..2574
                     /locus_tag="ACZPB4_15405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004560 - alpha-L-fucosidase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HIR1099640.1"
                     /translation="MKHLSSSILLGLGLFSFFSCKEATAPAPILPVPTPAQVEWHKME
                     TYAFVHFGLNTFNDLEWGYGNTPASTFNPTDLDCDQWAQTIKAAGLKGVILTTKHHDG
                     FCLWPTATTEYSVKNSPWKDGKGDMVKELSDACKKHGLKFGVYLSPWDRNSENYGQPG
                     YVEKFHAQLHELVSNYGPLFEYWFDGANGGNGWYGGTNETRAIDAKTYYQYERARDTI
                     KAHHPDIMVFGGTVPDIRWIGNEEGWAGDTQWSIFAPEPSMPTFQQSVWGDENGPMWL
                     GGECDVSIRPGWFYHSREDHQVKSLAKLVDLYYRSVGHNANFLLNFPVALNGKISPVD
                     SARAVQWYQTIQNDFKENLLKGCYVQASNKRGRNFSPNKAVDGDWDTYWATDDGVTSG
                     SLTFTLTHPTDVNRLVIQEYIPLGQRVRSFNIELEQGGKWIPAQTVDSTTTVGYKRIV
                     RFQTEKAEKIRINFTDARGPLCINNVEAHLAPALVTEPTIARNINDEVTIQAGDKGSE
                     VHYTTDGSDPTKDSPLYQAPFAFAQKGTVKAIAYDPTFDTVSPVSAQTFDIPACDYTI
                     VSPKDEKTSLILDGNGYTTYYLPQGKQELVVQLAKEMPISGFRYTPNQGRDASGHISN
                     YQLYINGKKVAEGEFSNIKANPIEQVVHFPITKGNQIRLVATRIVDNKKQAGIGEFSV
                     ITEK"
     gene            complement(2660..5488)
                     /locus_tag="ACZPB4_15410"
     CDS             complement(2660..5488)
                     /locus_tag="ACZPB4_15410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HIR1099641.1"
                     /translation="MNLLQRYVSHGIAIGLLVFIMLAFNLSVLARTSEKRVLRVAFPQ
                     VDGMSWTAEDGTHHGMLVDYLNEIAKYTGWEYEYIDTKGPAMLNEFVEGKYELMGGNY
                     YIPALEKYYAYPNYNMGYSRSLLLARSDDRSIHSYDLESMNGKTIGVYENARENIRRL
                     KEFMAINGLYCNIRYYKQEDMVGKIGLYPYLAKGEIDLLLNNVAHISDSVRVVVAYDS
                     QPYYIVTNPGNKEVLDGLNMALERILDANPNFAAERYAVNFPDRLVNIQLSDRDLEYV
                     NERKTITVAVPENWYPLYCKETPLKNHTGIMADVLDEIKSFTGLRFSYVYAKNYADAI
                     RLIQQGDADILGFFLGDENDAAQLGLALSASYVSANNIIVRNKACSYPAPGLVGALVE
                     NQRLPSGISVEKIRFYPSIKEALFAVNNGEADFIYGLSSRMEQDILRYHFTNLAPVTL
                     VNDQSTISFALPIPVDPDLLTILNKAINNLSESERTVIRNRNLESIGVSEFSLTDFIY
                     ANPLQFMFIVMFVLSVLFTALLLAIGARMKATVIQGNLKRAEAANLAKSEFLSRMSHE
                     IRTPMNGIVGMSTIAMQNIDNTDKIKDCLEKVIMSSKHLLALINDVLDMSKIESGKVE
                     LRHESFNFRAFLQDFENLYGEQAKSKGISYETILASDLEVQIIGDSLRLNQVLSNLLS
                     NALKFTPAKGMIKLRVSKTGEDQENVYLRFEVIDTGCGIAEENYDKIFESFEQENVDV
                     TYKYGGTGLGLSIVKRFTGLMGGGIHVTSVQGSGSTFTVDLPFGKIKESGKPTRFSDI
                     NGRNDLAKDCYAVDYDFKGKRILLVEDNELNREIAEELIGVTGASVESAEDGVQAVEM
                     FKESAEGYYDLILMDVQMPHMDGYEATRCIRALGRSDAQKVPIFAMTANAFAEDVQKS
                     REAGMNAHISKPLNIRAVYKQMNRYLQG"
     gene            complement(5711..6685)
                     /locus_tag="ACZPB4_15415"
     CDS             complement(5711..6685)
                     /locus_tag="ACZPB4_15415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HIR1099642.1"
                     /translation="MLEKKISRRNMLRTTGLAVLGSTFAGLASCAPKKKEEPSPEASS
                     SKRPFRVCLNVSTIAGYKLPVQKQIDLCAEAGFEGIELWTRDVDAFVKQGGTYETLRR
                     QLEGSGLLLENMIGFASWFADDPSKRKEGLNQMRHDMEMVAGLGGKFIAAPAQGVTQL
                     DRTRLPEYSERYRAILDLGDEMGVTPILELWGAGVLNQLSDTMAIAIASGHSRASVLL
                     DFYHLYRGGNSFDSLRLINGKILPVFHINDYPELPPRTELRDSDRVFPGDGICPFNKV
                     LPLLYDSGFRGGLSVELFNKGYWETMDVKEVLKKSFEKTTQVINSSMG"
     gene            complement(6703..>8234)
                     /locus_tag="ACZPB4_15420"
     CDS             complement(6703..>8234)
                     /locus_tag="ACZPB4_15420"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008781088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016298 - lipase activity [Evidence IEA];
                     GO_function: GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="carboxylesterase/lipase family protein"
                     /protein_id="HIR1099643.1"
                     /translation="FIGDDIAIAQTEYGKVQGYLLNHVYTFLGVPYGADTSGKNRFMP
                     PQKPEPWTDVRPAVFYGNTAPQRMENRWPNNYGTFADHWNYWDVSEDCLYLNVWTPGI
                     ADGKKRPVLVWLHGGGFTNGSGIEQDGYHGENISREGDIVFCSINHRLGPIGFSDLSG
                     VGGEAYKDSGNVGMLDIIAALRWVHDNIANFGGDPGNVTVMGQSGGGSKVCTVAAMPA
                     AKGLIHRAVALSGSTVGASDQVMTRKVGEYILREAGLTASQLDKLQRIPWREYLDIAD
                     RACKKCWEDQGISMRRTFGPVADDRNIPAGVFYSGESHLESPVVPMIFCTTFHEWNPN
                     RADAALEKITQDGVIEKLRSQYGDKAESIVKAFAKNFPDKTPMELWAMILSSRQRVVE
                     AANAKLKQGQPVYVAWFGWCPPLFNNRMRAFHCSDICFWFKNTDRMFTHTGGGKVPRA
                     LSDKMSGALLNFMRTGDPNGGELPAWPKYTEENGEVMILNNTCEARNDPDREARKSLE
                     V"
BASE COUNT         2353 a         2182 c         1590 g         2109 t
ORIGIN      
        1 ttatcgcttg gcctagccaa cctcatcccc tacccaagga tacctccacg tttccatcat
       61 ttctgaagcg ccgttctctc tcgaatgcgg gtgcaaaagt atacgctttt attataacat
      121 ccaaatttta taacgacttt ttttgaactt ttttacggca acggacttcg ggtacattat
      181 aatatagcac acacaaaaat accgactgct cacggaaacg atatagccgg tacccttgcc
      241 atccgtgtgg caatactgtg ccactacgat ggcacggccc tgccacacgg atggcacagc
      301 gttgccacca tgatggcacg accgtgccaa aggcgataaa taaactggca ctgcaaacaa
      361 ttgataaaca aacatatgct agcatgagaa ttttcccaga ggagacatct aaaagacagg
      421 ggactttatc ttttatctag atatctaaag acagaataaa aatctgccgt tttttttcat
      481 atatttgagg tctcatctaa atataaacaa ataatgaagc acttgagttc ctctatttta
      541 ttggggcttg ggttgttttc cttcttctcc tgtaaagaag cgacagcgcc cgcccctatc
      601 ctgcccgttc ccacgccggc acaagttgaa tggcataaga tggaaacata cgcctttgtc
      661 catttcggat taaatacgtt caatgatctg gaatggggtt acggaaatac tcccgcctcc
      721 acattcaatc caacggatct ggattgcgat caatgggcgc aaacaatcaa agccgccgga
      781 ttgaaaggcg taatcttaac caccaagcat cacgatggtt tctgtctatg gcctaccgcc
      841 acaaccgaat atagcgtaaa gaattctcct tggaaagatg gcaaagggga tatggtaaaa
      901 gaactatccg acgcttgtaa gaaacacggg ctgaaattcg gtgtctatct ctccccttgg
      961 gacagaaaca gtgagaacta cggacaaccg ggatatgtag agaaattcca tgcccaatta
     1021 catgaattag tctccaacta tggcccgttg ttcgaatact ggtttgatgg ggcaaacggt
     1081 ggcaatggct ggtatggcgg cacgaatgaa acccgtgcta tagacgccaa gacctattat
     1141 caatatgagc gggcacgaga cacgatcaag gcgcaccacc cggacatcat ggttttcgga
     1201 gggacagtac ccgatatccg ctggatcggt aacgaggaag gttgggccgg tgatacccaa
     1261 tggagcatct tcgccccgga accctccatg cctactttcc aacagagtgt atggggagat
     1321 gagaacggac cgatgtggct aggtggggaa tgcgatgtat ctatccgtcc gggatggttc
     1381 tatcactccc gggaagatca ccaagtcaaa tctctggcaa aattagtcga tctttattac
     1441 cgaagcgtcg ggcataacgc caatttccta ttgaacttcc ccgtagcgtt gaacggaaaa
     1501 ataagtccgg tagactccgc ccgtgccgta caatggtatc aaaccatcca aaatgacttt
     1561 aaggagaatc ttttgaaagg atgttacgta caagcgagca ataaaagagg acgtaatttt
     1621 agtcccaata aggcagtaga tggggattgg gatacctatt gggctacgga cgatggagta
     1681 accagtggtt cattgacttt cacgttaacc catcctaccg atgtaaaccg cttggtaata
     1741 caagaatata tcccattagg acaacgagta cgctcgttca atatcgaact cgagcaaggg
     1801 ggtaaatgga ttccggcaca gactgtggat tctacgacaa ctgtcggcta taaacgaatt
     1861 gtccgtttcc agaccgagaa agcggagaag atacgcatca acttcacgga cgcccgcggg
     1921 ccgctttgta tcaataacgt ggaggcacac cttgcccccg ccttggtgac cgagccaacg
     1981 attgcccgta atatcaatga cgaagtaacc atacaggccg gggataaagg ctccgaggtt
     2041 cattatacca ccgacggttc agatccgacc aaggactcac cgctttatca ggcgccattc
     2101 gctttcgctc aaaaaggaac tgtcaaggcg attgcctatg atccgacttt cgatacagtc
     2161 agtccggttt ccgcgcaaac gttcgatatt cctgcttgtg attacacgat cgtatcaccg
     2221 aaagatgaga aaaccagcct gatcctagac ggaaacggct acacaaccta ctatttgcca
     2281 caagggaaac aagagttagt cgtacaatta gcgaaagaaa tgcctatatc cggattccgc
     2341 tacaccccga accaaggacg tgacgcaagc ggtcatatct ccaactatca attatatatt
     2401 aatggaaaga aggtggccga aggcgaattc tccaatatca aggctaaccc gatcgagcaa
     2461 gtcgtacatt tcccgataac gaaaggtaac caaatccgtt tggtcgcaac ccgtatcgta
     2521 gataataaaa agcaagcggg tatcggtgaa ttctcggtaa ttacggaaaa ataaagaata
     2581 tctaataaaa gcagaaggga ccgcctcgaa agtttaattt tcagaggcgg acccttttaa
     2641 ttatttatca atcttttatt tatccttgaa ggtaccggtt catttgctta tacacggcac
     2701 gtatatttaa tggtttagat atatgagcgt tcataccggc ctccctactt ttctgcacat
     2761 cctcagcgaa tgcgttggct gtcatagcga agataggaac cttttgagca tcagaacgcc
     2821 ctaatgcacg aatacaccgg gtagcctcat agccatccat atgcggcatc tgcacatcca
     2881 tcaatatcaa atcataatac ccttcggcag actccttaaa catctctacg gcctgtaccc
     2941 cgtcctcagc gctctccacc gacgcaccgg taactccgat caattcctcc gctatctccc
     3001 ggttaagctc attgtcctca accaataaga tccgtttacc tttgaagtca taatcaacag
     3061 cataacaatc cttcgcaagg tcattcctcc cattaatatc ggaaaaacga gtgggcttac
     3121 ccgattcctt tattttgccg aaaggcagat caacggtgaa tgtactgcca ctcccctgca
     3181 cgctcgtcac atgtatgcca ccacccatca accctgtgaa acgcttaacg atagaaagcc
     3241 ctaatcctgt acctccatat ttataagtaa catccacatt ttcctgttcg aacgattcga
     3301 agattttatc atagttctcc tcggctatac cacatcccgt atcgattacc tcgaaacgta
     3361 ggtaaacatt ctcttgatcc tcacctgttt tagatacccg aagtttaatc attcccttgg
     3421 ccggcgtaaa tttcagcgca ttcgataaca ggttggagag aacttgattc aagcgcaagg
     3481 agtctcctat aatctgtact tccagatcac tagccaatat cgtctcatag ctgatccctt
     3541 tactcttggc ctgctcgcca tacagatttt caaagtcctg caagaatgcc cggaaattaa
     3601 agctctcatg tcgaagttcc acttttccgc tttctatctt cgacatatcc agcacgtcgt
     3661 taatgagagc gagaagatgc ttggaagaca tgattacttt ctcaagacag tcctttatct
     3721 tatcggtatt atctatgttt tgcatggcga tagtactcat acctacaatt ccgttcatcg
     3781 gcgtacggat ctcatgactc atccgggaaa gaaactcgct cttcgccaag ttagccgcct
     3841 cagcccgttt caggttgccc tgtatcacgg tcgctttcat ccgggcccct atagccagca
     3901 gtaatgccgt aaatagcacc gacaagacaa acatcacgat aaacataaat tgtaagggat
     3961 tcgcatatat aaagtccgta agagagaatt cactcacgcc gatagattcc agattccgat
     4021 tgcgtataac agtcctctcg gactcagaaa gattattgat cgccttgttg agtatggtaa
     4081 gcaaatccgg atcgaccggg ataggcaacg cgaaacttat cgtactctga tcattgacca
     4141 acgttacggg agcaagattc gtaaaatgat agcgcaagat atcctgttcc atcctagagg
     4201 acaaaccata aataaaatca gcctcaccat tattgacagc aaataacgcc tccttaatac
     4261 tcggatagaa ccgtatcttc tccaccgata taccactcgg caatcgttga ttttccacta
     4321 aggctccaac cagacccggt gcgggataac tacatgcttt attgcgcact atgatattgt
     4381 tagcactcac ataagaggct gaaagcgcaa gtcctagctg ggccgcatcg ttctcatctc
     4441 ccaagaaaaa acctaagata tcggcatccc cttgctgtat caaacggatc gcatcagcat
     4501 aatttttcgc atatacatac gagaatcgta gccctgtgaa acttttaatc tcatccagta
     4561 catccgccat gatacccgta tggttcttca gcggcgtttc tttacaatac aaaggatacc
     4621 aattctcagg tacggctacc gtgatcgttt tcctctcatt gacatactcc agatcccggt
     4681 cgctcagttg gatgtttacg agccggtctg ggaaattaac ggcataacgt tccgccgcaa
     4741 aattaggatt ggcatccaat atccgttcca aagccatatt caaaccatcc aagacttctt
     4801 tattacccgg attggtcacg atataataag gctgagagtc atatgccacg actacacgga
     4861 cagaatcgct aatatgggca acattattta gtaacaaatc gatctcacct ttagccagat
     4921 agggatataa cccgattttc cccaccatat cttcctgttt gtaatatcgg atattacaat
     4981 acaatccgtt gatagccata aactctttga gacggcgaat gttctccctt gcattctcat
     5041 acacaccgat ggttttacca ttcatactct ccaaatcata actatggata gagcgatcat
     5101 cagatcgggc aagtaataat gaacggctat atcccatatt atagttcgga taagcataat
     5161 atttctctaa agcgggtata taatagtttc cacccatcaa ctcgtactta ccctcaacaa
     5221 attcattcaa catagccggt cccttcgtat ctatgtactc gtattcccaa ccggtatatt
     5281 tggcgatctc attgagatag tctacgagca taccatgatg agtaccatct tcggccgtcc
     5341 aactcatgcc atctacctgc ggaaaggcaa ccctaagtac acgtttttca cttgtccgcg
     5401 ctaacacaga caaattaaac gctagcatta taaatactaa caaacctata gctataccat
     5461 gactcacata tctctgaagt aagttcatta taatgtatat cttttattac cggcttttcc
     5521 gatgataaca acccccataa ccctccgcaa aacaactgtt tattttggat gtacgcaaat
     5581 atactacttt ttatatcaca gcggattata aaataattga tttttaaaag aagatactat
     5641 aaaaacagaa gggaccgcct cgaaggtaaa acacctcgag gcagtccctt tcctaaatcc
     5701 caacaaactt ttatcccatc gaactattga ttacctgtgt ggttttctca aaactcttct
     5761 ttaagacctc ctttacatcc atggtttccc aatatccctt attaaaaagc tctacggata
     5821 acccaccccg gaaaccggag tcgtatagca aaggaagtac cttattaaac gggcaaatac
     5881 catctcccgg aaacacccga tccgaatctc tcaactccgt acgaggaggc aactccggat
     5941 aatcgttgat atgaaaaacc ggaaggatct taccatttat caagcgtaaa ctatcaaaac
     6001 tatttcctcc tctgtacaaa tggtagaaat ccaataagac agaagcccgc gaatgcccgg
     6061 aggcgatcgc tatcgccatg gtatccgata attgattcag aaccccggct ccccatagtt
     6121 ccaatatcgg agtgacaccc atctcatccc ctaaatccag tatcgcccga tagcgttcgg
     6181 aatactctgg caaccgtgta cgatccagtt gagtaactcc ttgagcagga gcggcgataa
     6241 atttaccgcc caatcccgct accatctcca tatcatgccg catttggttt agcccttcct
     6301 tccgtttcga aggatcatcg gcaaaccacg aggcaaaacc gatcatattc tccaataaaa
     6361 gtccggaacc ttccagctga cgcctgagtg tctcataagt tcccccttgc tttacgaacg
     6421 catccacatc acgggtccat aactcaattc cctcaaaacc agcctcggca cataagtcaa
     6481 tctgtttttg aacaggaagt ttataacccg ctatcgtaga gacattgaga cagacacgga
     6541 aaggacgttt cgaagaggat gcttcgggtg atggctcctc ttttttcttc ggagcgcaag
     6601 aagccaagcc tgcgaacgta ctgcccaaaa ccgccagacc ggtagtccga agcatattac
     6661 gtcttgaaat ctttttctca agcataacac tctcgtttta aattaaacct ccaaagattt
     6721 acgggcctcc cgatccggat cattccgagc ctcacacgta ttattcaaga tcatcacctc
     6781 tccattttct tccgtgtatt tcggccaagc gggtaactct cctccgttcg gatctcctgt
     6841 ccgcatgaaa ttcaacaaag cgccagacat cttatctgac aacgcacgag gtaccttacc
     6901 tccacccgta tgagtaaaca tccgatccgt atttttaaac cagaaacaga tatccgagca
     6961 atggaacgca cgcatacggt tattaaacaa gggcggacac cagccaaacc aagctacata
     7021 cacaggctgg ccttgcttta attttgcgtt agccgcctca accactcgtt gacgggaaga
     7081 caaaatcatc gcccaaagct ccatcggagt cttatccggg aaattcttgg cgaaagcctt
     7141 cacgatcgat tccgctttat caccatattg acttctcagt ttctcgatca caccgtcttg
     7201 agtgattttt tccaaggccg catccgccct gttcgggttc cattcatgga aagtcgtaca
     7261 gaatatcatc gggacgacag gagactccaa atggctctca ccggagtaga atacaccggc
     7321 cggaatattc cggtcatcag caacagggcc aaaagtccgt ctcatgctaa tcccttgatc
     7381 ttcccagcac tttttacaag ccctatccgc tatatccaaa tattcccgcc aaggtattct
     7441 ttgcaattta tccagttggg aagcggtcag ccccgcttct ctcaaaatat attctcccac
     7501 cttccgggtc atcacctgat cggaagctcc taccgtagat ccacttaaag ccacggctct
     7561 atggatcaaa ccttttgccg ccggcatagc ggctactgta cagaccttag aacctcctcc
     7621 ggattgtccc ataaccgtta cgttcccggg atctccaccg aaattggcga tattatcatg
     7681 aacccatcgc aaggcggcaa taatatctaa catccccacg tttccggaat ccttatacgc
     7741 ttctccacca acaccagata agtcagagaa gccaatcggc cccaaccgat gattaatgga
     7801 acagaatacg atatctcctt cccggcttat attctctcca tgatatccat cctgctcgat
     7861 cccactacca tttgtaaaac caccgccatg cagccacacc aatacgggac gtttcttacc
     7921 atccgcaatg cccggtgtcc atacatttaa atataagcaa tcctcactca catcccagta
     7981 gttccaatga tcggcaaaag ttccgtaatt attgggccac cggttctcca tacgttgcgg
     8041 cgccgtattc ccataaaaaa ccgccggtct cacatctgtc cacggctctg gcttttgggg
     8101 aggcataaag cgattttttc ccgacgtatc agccccataa ggaactccca agaacgtata
     8161 tacatgattc agcagatatc cctgcacctt cccatactct gtctgggcga tggcgatatc
     8221 gtcaccgata aata
//
LOCUS       DBMDTB010000137         8113 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_2392_length_8113_cov_11.191712, whole genome shotgun sequence.
ACCESSION   DBMDTB010000137 DBMDTB010000000
VERSION     DBMDTB010000137.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 8113)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 8113)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8113
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2392_length_8113_cov_11.191712"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..528
                     /locus_tag="ACZPB4_15425"
     CDS             <1..528
                     /locus_tag="ACZPB4_15425"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008998837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HIR1099644.1"
                     /translation="GAMIPVMSNSGSGNQGIAATLPVLSFAEDIQCSEEQLIRALMLS
                     HLMVIYIKQSLGRLSALCGCVVAATGASCAITYLMGGNKARISYAIKNMIGNITGMIC
                     DGAKPSCAMKVSSGVSTAMLSALMAMEDKVVTSVEGIIDEDVDKSIANLTAIGSKGME
                     ATDRLVLDIMTGKSC"
     gene            538..1440
                     /locus_tag="ACZPB4_15430"
     CDS             538..1440
                     /locus_tag="ACZPB4_15430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HIR1099645.1"
                     /translation="MEEAPKARKKEIMRVTLLGSFANFVLLVFKFVAGIWGHSSAMIA
                     DAVHSLSDFVTDIIVLLFVNISSKPKDESHDYGHGKYETLATSIVGIVLLCVGFGLFW
                     EGANKIYDFYFKGIPLESPGMIALVAALISIVIKELLYHITVWVGRKQNSQVVIANAW
                     HHRSDAFSSIGTALGIGGAILLGDNWRVLDPLAAVIVSLFVVKVALQLVIPAINDLLE
                     KSLPKEVEDEILAIISEIPEVKSPHNLRTRRIGNNFAIEAHIRVDGQITVTRAHDLTK
                     EIEQNLRDKFGQATHIALHVEPIK"
     gene            1453..2793
                     /gene="guaD"
                     /locus_tag="ACZPB4_15435"
     CDS             1453..2793
                     /gene="guaD"
                     /locus_tag="ACZPB4_15435"
                     /EC_number="3.5.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008892 - guanine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006147 - guanine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanine deaminase"
                     /protein_id="HIR1099646.1"
                     /translation="MTMMKNLYRGEVLYLIASPLDHVEAYRYFEDGGLAVVDGKIVEA
                     GPFEAMRSRYPDFPVTDYSGKLITPGFIDSHIHFSQSEIQGMYGKQLLDWLDEYTFPA
                     EEAFSSIEYAQDIARFFVKELVKNGTTTCVAYATVHPASVTALFSVATEYNMCILAGK
                     VMMNRNAPDYLMDTTHQGELDCRSLIEDWDGKGRNHYVITPRFAITSTPDQLKSAGRL
                     HAEYPSTYIQTHLSENLGEIESVLSLCPGHADYLEVYERAGLLTDRSIFGHCVHLTDR
                     EYKRLGETGGIIAHCPTSNLFLGSGLFDMREANRYGVRTTLATDVGAGTSFSMWRTMG
                     EAYKVQQLNGYPMTALEAIYKCTLGSARALSLDDRIGSFLPGREADFIVVDYAATSVQ
                     KLRMEYLRSRDKWTIENKLFGLQTLGDDRNTVCTYIMGKQVYGSDSCDHQEASM"
     gene            complement(2758..3726)
                     /locus_tag="ACZPB4_15440"
     CDS             complement(2758..3726)
                     /locus_tag="ACZPB4_15440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HIR1099647.1"
                     /translation="MKTRRIVISTVLLVGGLLSIVQVMPKNPLLIGERLFPYGGWIQV
                     ILAMLYGGWLCYKMQDRQERPKWRKRAWLLFSIVFFGQLALGIFADPIFLMTGKLHLP
                     IPAVILAGPLYRFEGLFMPILFISTLLLSGPAWCSQLCYFGAFDAWSARGKLERKRFP
                     YHKQMRYSILFLVMLGAILLRIFGASGRIATAFGIAVGVIGLLVMLLFSRKRRKMVHC
                     SSYCPIGTLVSFLKYLSPFRVRLTTDCCHCMACTNACRYDALHKEEIEKGKIGYTCTY
                     CGDCLSACKHGAIEYHFPGLRPTTAERLWIVVTVVLHTCFLMIARI"
     gene            complement(3771..5039)
                     /locus_tag="ACZPB4_15445"
     CDS             complement(3771..5039)
                     /locus_tag="ACZPB4_15445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IX secretion system plug protein"
                     /protein_id="HIR1099648.1"
                     /translation="MKVFKILFLLLITVLVPLNAQVTYFTNVSDKQIKTLQVKVAGEM
                     FSDPFIELGGENRIEVNFDAFNPGFGRYAYNLVHCNADWTQSNLSPIEYMNGFQGSTI
                     EDFANAMGTTVQYTNYRLLFPNDDVQPKVSGNYALQVYNEDDPSQIVFTACFSIFEPM
                     VSVAATVSGNTDIDTNQSHQQVSFAINNKNFPITYPQTDLKIWVYQNNRRDNAVTGLQ
                     PMTILENQISYTNNQNLIFPAGNEYRRMEFLSNKYNGMHVESISFHNPYYHVELMTDY
                     RRDQLSYQYDQDQDGRFFIRCSNCNDPDTEADYYIVHFTLAMDLIPDGNVYLNGELYN
                     NVLDEKSKMGYNPETHQYEKSVLLKQGSYNYQYLFVPNGQTVGQTGPIEGNFFQTENE
                     YSIYVYYCPMGARYDRLIGVTSIRNTMPVL"
     gene            5172..6518
                     /locus_tag="ACZPB4_15450"
     CDS             5172..6518
                     /locus_tag="ACZPB4_15450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008149665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na(+)-translocating NADH-quinone reductase
                     subunit A"
                     /protein_id="HIR1099649.1"
                     /translation="MANVIKIKKGLDINLKGKASDVLLNGGKSESYAIVPDYYNGILP
                     KVVAKVGEKVKAGSVLMIDKNRPEIKFVSPVSGEVTAVNRGEKRKVLSIVVKPDAQIE
                     YEEFGKKNVASLQGAEVKEVLLNAGMWPFIKQRPYDIVAAPLDTPRDIFVSAFYSAPL
                     APNFDFIVKGQEADFQTGLNALAKLTNGKVYVGVRSGSVVSGMKGVEIVEVEGPHPAA
                     NVGVQINHIKPVNKGEVVWTVNPADVIVIGRLFNKGVADFSRMVAITGSETTERGYVK
                     TISGCTIKSLVNGKVLGQEHIRIISGNVLTGTKVNMDGYLGAYDNQITVIPEGDETHE
                     FLGFAMPRFNQFSASHSYFSWLGTSKEYVIDARIKGGKRAMIMSNEYDKVFPMDIYPE
                     YLLKAIIAFDIDKMENLGIYEVAPEDFALCEFVDTSKIELQKIVRDGLNLLYKEMN"
     gene            6542..7744
                     /locus_tag="ACZPB4_15455"
     CDS             6542..7744
                     /locus_tag="ACZPB4_15455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA];
                     GO_process: GO:0022904 - respiratory electron transport
                     chain [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH:ubiquinone reductase (Na(+)-transporting)
                     subunit B"
                     /protein_id="HIR1099650.1"
                     /translation="MKALRNYLDKIKPNFEEGGKLAMFRSVFDGFETFLFVPNETSKT
                     GVHIHDCIDSKRAMTVVIIALLPALLFGMYNVGYQHNLAVGADPGFLMTFIFGFLAVL
                     PKIIVSYVVGLGIEFAVAQVKKEEIQEGFLVSGILIPMIVPVDTPLWMIAVATAFAVI
                     FAKEVFGGTGYNIFNVALVTRAFLFFAYPAAMSGDQVFVRTADTFGIGAGQVVDGFSG
                     ATPLGQVAIAGKEMIGSFQAVDVLGNPISTWDAFIGLIPGSIGETSVLAILIGAVILL
                     VTGIASWKTMVSVFVGGAFMSLIFNMVGTTVAMCVSPLDHLFLGGFAFGAVFMATDPV
                     TSARTETGKYIYGFLVGAMAIIIRALNPGYPEGMMLAILLMNVFAPLIDYYVVEANIS
                     RRLKRVIK"
     gene            7758..>8113
                     /locus_tag="ACZPB4_15460"
     CDS             7758..>8113
                     /locus_tag="ACZPB4_15460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rubredoxin-like domain-containing protein"
                     /protein_id="HIR1099651.1"
                     /translation="MAKYKCKVCGYVHEGNKAPDTCPVCSAPASEFEEIKEEGAAKKG
                     INRDSNVYTVVYAAVMVVLVAVVLAFTSQSLRSFQKQNEDNDKRQQILRSINVNVSSS
                     EAETKYNELIKEAFLV"
BASE COUNT         2070 a         1641 c         2085 g         2317 t
ORIGIN      
        1 ggcgctatga tcccggtgat gagtaattcg ggaagcggta atcaaggaat cgccgctacg
       61 cttccggttc tttctttcgc cgaggatatc caatgctcgg aagagcaact gatccgtgcg
      121 ttgatgttaa gccatttgat ggtgatctat atcaagcaaa gtctgggacg cttgtccgcc
      181 ctttgcggtt gtgtggttgc cgctacggga gcgagttgcg ctatcaccta tttgatggga
      241 ggaaataagg cgcggatttc ttatgcgatc aagaatatga tcggtaatat taccggaatg
      301 atctgtgacg gtgccaagcc gagttgtgcg atgaaagtat ctagtggcgt atctacggcg
      361 atgctttccg ctttgatggc catggaggat aaggtggtga cttccgtgga aggtatcatc
      421 gatgaggatg tggataaatc gatcgcgaac ttgaccgcta tcggttctaa aggaatggag
      481 gcgacggatc gtctggtgct ggacatcatg accggtaaat cttgttaatg ggattctatg
      541 gaggaggcac caaaggcgag gaaaaaagag attatgcgag tgacactttt agggtcattc
      601 gctaattttg ttttattggt attcaagttc gtggcgggta tctgggggca tagtagcgct
      661 atgatcgccg atgcggtaca ttcgttatct gatttcgtaa cggatataat cgtacttctt
      721 tttgtcaata tatcttccaa gccaaaggac gagagccatg attacgggca tggtaaatac
      781 gagactttgg cgacttcaat tgttggtatc gtcttgcttt gtgtaggttt tggccttttc
      841 tgggagggag cgaacaagat ttatgacttt tatttcaagg ggattccgtt ggaaagtccg
      901 ggaatgatcg ctttagttgc cgctcttatc tccattgtga tcaaggaatt actgtatcat
      961 attacggttt gggtaggaag gaagcagaat agtcaagtcg ttatcgctaa cgcttggcat
     1021 catcgctcgg atgccttttc ctcgatcggt acggctttag gtatcggagg ggcgattttg
     1081 ttgggggata attggcgtgt gctggacccg ttggcggctg tgattgtcag tttatttgtc
     1141 gtaaaagtag ccttacaact agtgatcccg gcgattaatg acttattgga gaaatctttg
     1201 ccgaaggagg tggaggatga gatcttggcg atcattagtg agattcccga ggtaaagagc
     1261 ccgcataatc tacgtacccg ccgcatcggt aataattttg ctatcgaggc gcatatacgg
     1321 gtggacggac agataaccgt gactcgtgcc catgacttga cgaaagagat cgaacagaat
     1381 ctgcgtgata agttcggtca ggctacgcac atcgctttgc acgtggaacc aattaaataa
     1441 acgaattgtt atttgaccat gatgaagaac ttatataggg gagaagtgct ctatttgatc
     1501 gcttccccgc tggatcatgt ggaggcttac cgctattttg aggatggggg actggctgtt
     1561 gttgatggaa agattgtaga ggcggggccg ttcgaggcga tgcgttcccg ttacccggat
     1621 ttcccggtga cagactattc cggtaaattg attacacccg gctttattga ttcccatatc
     1681 catttctccc agtcggagat acagggaatg tatggcaagc aacttctgga ttggctggac
     1741 gaatatacgt ttcccgccga ggaagctttc tcttccatag aatatgcaca agatatcgct
     1801 cgctttttcg tgaaggaact ggtaaagaac ggaactacga cttgtgtcgc ttatgccacg
     1861 gttcatcctg cttccgtaac cgcattattt tccgtggcta cggagtataa tatgtgtatc
     1921 ttggctggaa aggtgatgat gaaccggaac gctccggatt atctgatgga taccacgcat
     1981 cagggtgagt tggactgccg tagcttaatc gaggattggg acgggaaagg acggaatcac
     2041 tatgtgatca cgccccgttt cgccataacc agtacgccgg atcaattaaa gtctgccggt
     2101 cgtttacatg ccgaatatcc cagtacctat atacagacac atctttcgga aaatctggga
     2161 gagattgaat ctgtcttatc gctctgtccc ggtcatgcgg attatctgga ggtctatgag
     2221 cgtgccggat tgttgaccga tcgttcgata ttcgggcatt gtgtccatct aaccgatcgg
     2281 gaatataagc ggttgggaga aacgggaggt attatcgccc attgcccgac ctcgaacctt
     2341 ttccttggaa gcggattatt cgatatgagg gaagcgaacc gttacggcgt acgtactacc
     2401 ttggcgacag atgtcggtgc gggtacatct ttctctatgt ggcgtacgat gggagaggcc
     2461 tataaggtac aacagttgaa cggttatccg atgacagctt tggaggctat ctataaatgt
     2521 acgctaggct ctgcacgggc cttatcgttg gacgaccgaa tcggaagttt cctccctggc
     2581 cgtgaagcgg atttcatagt cgtggattat gccgctacct ctgtccagaa attgcgtatg
     2641 gagtatcttc gttcgagaga taaatggacg atcgagaata agctgtttgg cctgcaaacc
     2701 ctcggcgatg accggaatac ggtatgtact tatataatgg gcaagcaagt atacggctca
     2761 gattcgtgcg atcatcaaga agcaagtatg taatacgacc gttacgacga tccataggcg
     2821 ctcggcagta gtcgggcgca atcccgggaa atgatattct atagccccgt gcttgcaagc
     2881 ggagaggcaa tctccgcaat aggtacaggt atagccgatc tttcccttct cgatctcttc
     2941 tttatgtagg gcatcataac ggcaagcgtt tgtgcaagcc atgcaatggc aacaatccgt
     3001 ggtcagtcgt acccggaaag gagagaggta tttgaggaaa gacactaaag tcccgatcgg
     3061 acaataacta ctgcaatgca ccatcttccg tctctttctg gaaaacaata gcatgacaag
     3121 taggccgata actccgaccg ctattccaaa agcggtggct atcctgccac tcgccccgaa
     3181 tattcggagt aggatggccc ccaacataac cagaaataat atgctgtatc gcatttgctt
     3241 gtgatagggg aacctttttc gttccaattt tccccgggca ctccatgcgt caaatgcccc
     3301 gaagtaacaa agctggctac accaagcggg accggatagt aataaggtgc tgataaaaag
     3361 tatgggcatg aataatccct cgaagcgata aagcggtccg gccaagatta ccgcggggat
     3421 cggtaaatgc agttttccgg tcataaggaa aataggatcg gcaaaaatcc ctagagcaag
     3481 ttgcccgaaa aaaacgatcg agaataacaa ccacgctcgt tttctccatt tgggacgttc
     3541 ttgccgatct tgcatcttat agcagagcca accaccgtat agcatggcaa gtatcacttg
     3601 tatccatcct ccatacggaa ataacctttc gcctatcaat agtggatttt taggcatgac
     3661 ttgaacgatc gagagaagtc ccccgactaa taatacggta ctgataacaa tacgtctcgt
     3721 tttcatgctc aattatttta tgcgtaaaag tatgcctttt acgcgaataa ttatagcacg
     3781 ggcattgtat ttctgatact tgttacaccg attaaacgat cataccgtgc tcccatcggg
     3841 caataataga cgtaaatgct atattcgttc tccgtctgga agaaattacc ctcgataggg
     3901 ccggtctgtc ctacggtctg tccgttaggg acaaagaggt actgatagtt gtaactgcct
     3961 tgtttcagta agacggattt ctcgtattga tgcgtctccg gattatagcc catcttactt
     4021 ttctcgtcca atacattatt atataattcg ccgttcaaat acacgtttcc atcgggaatt
     4081 aagtccatgg cgagggtaaa gtgaacgatg taatagtccg cttccgtatc cgggtcgtta
     4141 caattactgc aacggatgaa aaaacggccg tcttggtctt gatcgtattg atacgataat
     4201 tggtcacgcc gatagtccgt catcaactct acatggtagt atggattatg gaacgagata
     4261 ctttctacgt gcatgccatt gtatttgttg ctcaaaaatt ccatacggcg atattcgttt
     4321 cctgcgggaa agatcaagtt ctgattgttc gtataagaga tctggttttc taaaatagtc
     4381 ataggctgaa gacctgttac ggcattatcc ctgcggttat tctgataaac ccagattttc
     4441 aagtcggtct gaggataggt gatggggaaa ttcttgttat tgatcgcaaa gctgacttgt
     4501 tggtgtgact gattggtatc gatatccgta tttccgctca ccgtagcggc gacactaacc
     4561 atcggctcga aaatagaaaa gcaagcggta aatacgatct gggagggatc atcctcgtta
     4621 tatacttgca aggcataatt ccccgagacc ttcggttgaa cgtcatcgtt tgggaaaagt
     4681 aatcggtagt tggtgtattg caccgtagta cccatcgcat tggcgaaatc ctcgatcgtg
     4741 ctcccttgga aaccattcat atactcaatc ggggaaagat tcgattgcgt ccaatcggcg
     4801 ttgcaatgaa ccagattata ggcgtatcgc ccgaagcccg gattaaaagc atcgaaatta
     4861 acctcgatac gattctcacc acccagttcg atgaatggat cggagaacat ctcgccggca
     4921 accttcactt ggagggtctt tatttgctta tcgctaacgt tggtgaagta agtcacttga
     4981 gcgttcaacg gtactaaaac cgtgataagc agcagaaata ggattttaaa aactttcatt
     5041 ttcttattac tttctttaac gacgcaaaat tatggaatta tttctctatt tatttgcctt
     5101 tccctgctct aaagcatgaa aaaatgttta cttttgcagg aaaattacat ataaacaatt
     5161 ttagttgtat catggcaaat gtgattaaga ttaaaaaggg tttagacatt aatctgaagg
     5221 gcaaagcttc ggatgtactg ttaaacggcg gcaagagcga gtcttacgcg atcgtccccg
     5281 attattataa cggtattctc cctaaagttg ttgcgaaagt aggagaaaaa gtcaaagccg
     5341 gttctgtact gatgattgac aagaaccgcc ccgagatcaa gtttgtttcg ccggtcagtg
     5401 gcgaggtaac tgccgtaaac cgaggagaga agcgtaaggt gctaagcatc gttgtgaagc
     5461 cggatgcgca gatcgagtat gaggagttcg gtaagaagaa cgtagcatcc ctacagggag
     5521 cagaggtgaa agaggtactt ctgaacgctg gtatgtggcc gtttatcaag caacgcccat
     5581 acgatatcgt tgccgctcca ttagatactc cgcgtgatat cttcgtttcg gctttttact
     5641 ccgctccgtt ggctccaaac ttcgatttta tcgtaaaagg tcaggaggct gatttccaga
     5701 ctggattaaa cgccctagct aaattaacga atggaaaagt gtatgtgggt gtaagaagtg
     5761 gttctgtcgt gagcggaatg aaaggtgtgg agatcgtgga agtagaaggt ccgcatcccg
     5821 cagcgaacgt tggcgtgcag atcaatcata tcaagcccgt taacaagggt gaggtagttt
     5881 ggacggttaa tccggcagac gtgatcgtta tcggacgttt gttcaacaag ggtgtcgccg
     5941 atttcagccg tatggttgct attaccggtt ccgagactac cgagagaggc tacgttaaaa
     6001 cgatttcagg ttgtacgatt aagagcttgg ttaacggtaa agtgttagga caggaacata
     6061 tccgtattat tagcggtaat gttttgacag gtaccaaggt gaatatggat ggttacctag
     6121 gcgcttatga taaccagatc accgtgattc cggaaggtga tgagacgcat gagttcttag
     6181 gtttcgctat gcctcgtttc aaccagttca gcgctagcca tagttacttt agctggttag
     6241 gtactagcaa ggaatatgtg atcgacgccc gtatcaaagg tggtaaacgt gccatgatca
     6301 tgtctaatga atacgataag gtgtttccga tggatatcta tccggagtat ttgttgaaag
     6361 cgatcattgc gttcgatatc gacaagatgg agaacttagg tatctatgag gtggctcccg
     6421 aggacttcgc tctttgcgag ttcgtggaca cttccaagat cgagttgcaa aagatcgttc
     6481 gcgacggatt gaacctgttg tataaggaaa tgaattaata acataaaaaa cttataatac
     6541 attgaaagcg ttaaggaatt atctcgacaa gattaagcct aactttgagg aaggcggaaa
     6601 gctggcgatg ttccgttctg tttttgacgg tttcgaaaca ttcttatttg ttccgaacga
     6661 gacctctaaa acgggcgtac atattcatga ctgtattgat tcaaagcgtg ccatgaccgt
     6721 ggttatcatc gctttgttgc ctgctttgct ttttggtatg tataatgtcg gttatcagca
     6781 caatttagct gtgggggctg atccgggatt tttgatgact tttatttttg gatttttggc
     6841 ggtattgcct aagatcattg tttcgtatgt ggtaggtttg ggtatagagt tcgctgtcgc
     6901 ccaagtgaag aaggaagaga ttcaagaagg attcttggtt tccggtatct tgattccgat
     6961 gatcgttccg gtcgatactc cgttatggat gatcgccgta gctactgctt tcgctgttat
     7021 tttcgcgaaa gaggtatttg gtggtacggg atataatata tttaatgtag cattggttac
     7081 acgtgcgttc ttattcttcg cttacccggc agcaatgtct ggtgatcaag tgttcgttcg
     7141 tacggctgat acgtttggta ttggggctgg ccaagtggtt gacggctttt ccggagctac
     7201 tccgctggga caagtcgcta tcgctggtaa ggagatgatc ggttctttcc aagctgttga
     7261 cgtattaggc aacccgatct ctacttggga cgcatttatt ggtttgatcc cgggctctat
     7321 cggtgagact tccgtattgg ctattttgat cggtgcggtt atcttgttgg ttacgggtat
     7381 cgcaagttgg aagacaatgg tttccgtgtt cgtgggtggt gctttcatgt cattgatctt
     7441 taatatggtc ggtacaacgg tcgctatgtg cgtatctccg ctggatcact tgttcttagg
     7501 tggtttcgct tttggtgccg tgttcatggc tacagaccct gtgacttccg ctcgtacgga
     7561 gacaggtaaa tatatctatg gtttccttgt aggtgctatg gccattatta ttcgtgcgtt
     7621 gaacccgggt tatccagagg gtatgatgct cgctatcctg ttgatgaacg tgttcgctcc
     7681 gctgatcgac tattacgttg tggaagctaa tatctctcgc agattgaaac gtgtaataaa
     7741 ataaagtaag aaggaatatg gctaaatata aatgtaaggt atgtggctat gtccacgagg
     7801 gaaataaggc tcctgacact tgcccggtat gttccgctcc tgcttccgaa tttgaggaaa
     7861 tcaaggagga gggcgccgct aagaaaggca taaaccggga tagcaatgtt tatacggttg
     7921 tttatgcggc tgtgatggtt gtgctagtgg ctgtcgtatt ggcgtttact tcacaatcat
     7981 tgagaagttt tcagaaacag aacgaggata acgataagag acaacaaatt ctgcgttcta
     8041 tcaacgtaaa tgtttcttct tctgaggctg agaccaagta caacgagttg atcaaggaag
     8101 ctttcttggt aaa
//
LOCUS       DBMDTB010000138         8113 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_2393_length_8113_cov_10.679231, whole genome shotgun sequence.
ACCESSION   DBMDTB010000138 DBMDTB010000000
VERSION     DBMDTB010000138.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 8113)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 8113)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8113
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2393_length_8113_cov_10.679231"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            75..623
                     /locus_tag="ACZPB4_15465"
     CDS             75..623
                     /locus_tag="ACZPB4_15465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5063 domain-containing protein"
                     /protein_id="HIR1099652.1"
                     /translation="MEKEENPIYERNTLEFVTVALEYCTFVEAAGNTGLFDFVDKATK
                     LLPLLYLKASLLPEVESEEETELELSVSEDMYESVRSRIAGLLGERDSYLETFHADMR
                     YSDTPIAAFISENLADVYQDTGNFVSLFRQGNEEVMQEAIALCRTNFQEYWGQQLLNA
                     LKALHAVRYSGDEDLEKNEEEE"
     gene            620..1201
                     /locus_tag="ACZPB4_15470"
     CDS             620..1201
                     /locus_tag="ACZPB4_15470"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HIR1099653.1"
                     /translation="MIQQFIHTIAKEEIAKLTVEEFKGRIITILSKEEADKAVEYLLR
                     FPIVGFDTETRPSFKKGQRYKISLMQISTDDTCFLFRLNHIGIPESLEKFLKSSSTLK
                     IGLSLRDDFGAIRKRSDIEPANFLDLQNYVGQFGIEDASLQKIYAILFQKKISKGQRL
                     TNWEADVLTDSQKKYAALDAWACLRIYNLLNQA"
     gene            1202..2386
                     /locus_tag="ACZPB4_15475"
     CDS             1202..2386
                     /locus_tag="ACZPB4_15475"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016277912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HIR1099654.1"
                     /translation="MKYCKVFLKPKKEESLLRFHPWVFSGAIQSVEGDPEEGDLVEVY
                     GANQRFLAIGHYQIGSIAVRVLSFTPIPIDDAFWIERIRIAYELRKTLRLAGVENNNT
                     FRLIHGEGDNLPGLVIDMYAHTAVMQAHSVGMHYARHQIAEALKAVLGDTLQNIYYKS
                     EATLPYKANLGSEDGYLFGGEVEDIAIENGLKFCVDWQKGQKTGFFVDQRENRSLLEH
                     YAKDRSVLNMFCYTGGFSFYAMRGGAKVVHSVDSSAKAISLTKKNVELNFPGDPRHEA
                     YAEDAFKYLEKMGSNYDLIILDPPAFAKHKNVLRNALQGYRKLNAIAFEKIKPGGILF
                     TFSCSQVVSKDNFRLAVFSAAAQSGRSVRILHQLTQPADHPVNIYHPEGEYLKGLVLY
                     VE"
     gene            complement(2438..4063)
                     /locus_tag="ACZPB4_15480"
     CDS             complement(2438..4063)
                     /locus_tag="ACZPB4_15480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RagB/SusD family nutrient uptake outer membrane
                     protein"
                     /protein_id="HIR1099655.1"
                     /translation="MRKLSILSYIFAGLMLSSCDGYLKEDPRDQLYPEDAYDTPQNVY
                     LNTVASLYNYIGGYSDSQGLQGTYRGVYDLNTFTTDEAMLPTRGGDWYDGGFWQGLFL
                     HKWGTNSDAIQATWEYLYKVIVLSNQSLEILGELRQKTDYNDLDRYEAEVRAFRAMYY
                     YYLVDMFGRVPLIVSSSIPVKDVRQSDRKEVFDFVVKELQESLLLLSTAHSNSPGDYY
                     GRITRPVVYFLLAKLALNAEVFTDNDWTDGLRPNGREIYFRVGERKLNAWQTVVAYCD
                     SITDLNYSLSLNYADNFSVFNESSGENIFTIPMDKNLYTNQMQYLFRSRHYNHAKAYG
                     LGGENGSCATIEALRVFAYGTDSVDTRFYENYYADTMFDLNGDTIRLDNGTPLVYLPL
                     EVRLDLSRLPAEKTAGARMKKYEIDKMGTKDGKLSDNDIVLFRYADVLLMRSEAKVRN
                     GENGDEELNAVRFRVGMLPRKATLENILAERQLELAWEGWRRQDLVRFGKFTRPYTDR
                     PQLPHESNGYTTVFPIPDKVRSLNPNLTQNPGY"
     gene            complement(4076..6853)
                     /locus_tag="ACZPB4_15485"
     CDS             complement(4076..6853)
                     /locus_tag="ACZPB4_15485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SusC/RagA family TonB-linked outer membrane
                     protein"
                     /protein_id="HIR1099656.1"
                     /translation="MKVLIYIRKVLFLFLCGALSFSYGYGQELPLLPDTIKPLLSDSN
                     LIDELITVGYATGNRSTLSGSVNRVNEGGMNEGLISTPLDALRGRVSGVSIPVGGNSA
                     AALAAVRVRGTTSLTGGNDPLVIIDGVFADLNLLSSIYPADIENFTILKDASETAQYG
                     SRGASGVIEVTTKKGRQGAFSISYDGSFGVEAAYKSLDMLSANGFRKLAEERNIGILD
                     LGNNTDFQDEITRLGLVQNHHIAFGGGSETSSYRASLGFVEREGVIRNTNSRNFTTKL
                     NITQHAFNDLLVFDLGIFGSLLKNAYLNDVQKMFYSAATFNPTFPNHKNMETGSWDQI
                     TNASQITNPLAWLEVKDDDSNAHINTHLKLVFNLSKHLMFTAFGSYTYNVIDNAQYLP
                     TSVWAHGQAYRGERKTESLLGDFMLAYKKDFGLHQLNVLGLAEAQKMITRGFYTTATN
                     FSTDRFGYDNLQAGAVRLWEGTGSYYEAPHLASFLGRVNYIYDGKYIATVNARADASS
                     KVGANNKWGFFPSASVAWVLTEEEFMEGVSWVRNLKIRSGYGLSGNQDAIDSYNSLRL
                     MKPNGVVSVNGAPTVTLGTIRNANPDLKWEVKRTFNAGIDAGFFDNRFILAVDYYNSK
                     TDDMLYLYDVSVPPFAYNKMLANLGSMRNSGVELGIGVTPLRTKDMELNINVNVTFQR
                     NKLLSLSGYYKGEYMSAPEYTSISDLNGAGFHGGYNHIVYQMVGQPLGVFYLPKCTGL
                     VSDGNGGYKYEIEDLNGNGVSLEDGEDRYIAGQAMPKTLLGSNISFRYKQFDLSVQIN
                     GAFGHKIYNGTSLTYMNMDIFPDYNVLREAPSRNIQDQTATDYWLEKGDYINFDYLTL
                     GWNVSLGNLRKYVRNVRLSVSVNNLATITGYSGLTPMINSSIVNNTLGIDDKRSYPVV
                     RSYTMGLSFNF"
     gene            7126..8067
                     /gene="mdh"
                     /locus_tag="ACZPB4_15490"
     CDS             7126..8067
                     /gene="mdh"
                     /locus_tag="ACZPB4_15490"
                     /EC_number="1.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004288341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malate dehydrogenase"
                     /protein_id="HIR1099657.1"
                     /translation="MSKVTVVGAGNVGATCANVLAFNEVADEVVMLDVKEGVSEGKAM
                     DMMQTAQLLGFDTKVVGCTNDYEKTANSDVVVITSGIPRKPGMTREELIGVNAGIVKS
                     VAQNILKYSPNAILVVISNPMDTMTYLSLKSLGLPKNRIIGMGGALDSSRFKYFLSQA
                     LGCNANEVEGMVIGGHGDTTMIPLARLATYKGIPVSKLLSAEKLQEVVASTMVGGATL
                     TKLLGTSAWYAPGAAGAFVVESIIHNQGKMVPCSVYLEGEYGESDLCIGVPVILGKNG
                     IEKIVELELTAEEKELFAKSAAAVHKTNEALKEVGAL"
BASE COUNT         2414 a         1855 c         1667 g         2177 t
ORIGIN      
        1 ctttatcacg aaaaaaacgg atttttgttg tatttttgcg aattgttatc aagaatgatt
       61 agacgaacag gcacatggaa aaagaagaaa atccgatata cgagcgcaac acgctagaat
      121 ttgttacggt agcactggaa tattgtacct ttgttgaggc cgccggaaat accgggcttt
      181 tcgacttcgt agataaggcg acaaaacttt tgcctctttt atatttaaag gccagcctgt
      241 tgcccgaagt ggaatctgaa gaggaaaccg agcttgagct ttccgtttca gaagacatgt
      301 acgagtcggt tcgttcacgg atagccggtt tgcttggcga acgagattcc tatctggaaa
      361 catttcatgc ggatatgcgg tatagcgata ctcctatcgc agcgtttatt tccgagaatt
      421 tggcagatgt ctatcaagat acaggaaatt tcgtatcttt attccgtcaa ggaaacgagg
      481 aagttatgca agaggctatc gctttgtgcc gcacgaactt ccaagaatac tggggacagc
      541 aattattgaa tgccttgaaa gcgttgcacg ctgtgcgtta cagtggtgat gaggatttgg
      601 aaaagaatga agaggaagaa tgatacaaca atttatacat acaattgcta aagaggaaat
      661 agcgaaactt accgtagagg aattcaaggg acgtatcatt acgatcctta gtaaagagga
      721 ggcagacaag gccgtagagt acttgctgcg ttttccgatc gtcggttttg atacggagac
      781 ccgtcccagc tttaagaaag gacagcgtta caagatctca ttgatgcaga tatcaacgga
      841 tgatacttgt ttcttgttcc gcttgaatca tatcggtata ccggaatctc tggagaaatt
      901 cctgaaaagc agttcgacct taaagatcgg gttatcttta cgggatgatt tcggggcgat
      961 acggaagcgt tcggatatag aacccgccaa tttccttgat ttacagaatt acgtaggcca
     1021 gttcggcatt gaggatgcca gcctgcaaaa gatatatgcg atacttttcc aaaaaaaaat
     1081 atcaaaagga caacgcctca cgaattggga ggcagatgta ttgacagact cacaaaagaa
     1141 atatgcggcc ctcgatgctt gggcttgcct aagaatatat aatttattga atcaagcata
     1201 aatgaagtat tgtaaagttt ttctcaagcc taagaaagaa gaatcgctat tgcgtttcca
     1261 tccatgggta ttttccggag cgatccaatc tgttgaaggc gacccggaag agggtgactt
     1321 ggtagaggta tacggagcga accagcgttt tttggcgatc ggccattacc aaatcggcag
     1381 tatcgccgta cgtgtgttat ctttcacccc aatccccatc gacgatgctt tttggatcga
     1441 acgtatccgt attgcttacg aactcagaaa gaccttgcgg ctggctgggg tagaaaataa
     1501 taatacgttc cgcctgattc acggcgaagg cgataattta ccgggattgg tgatcgatat
     1561 gtatgcgcat acggcggtta tgcaagcaca ttcggtagga atgcattatg cccgtcatca
     1621 gatcgcagag gctttgaaag cggtattggg cgatacttta caaaacatct actataaatc
     1681 ggaagcgact ttaccttata aagcgaattt aggtagcgaa gatggttact tattcggagg
     1741 cgaagtggaa gatatcgcta tagaaaacgg actgaaattc tgtgtagact ggcagaaagg
     1801 ccaaaagaca ggtttcttcg tggatcaacg ggagaatcgc tctttgttgg agcattacgc
     1861 aaaggatcgc tccgtattga atatgttctg ttatacgggc ggtttctctt tctatgcgat
     1921 gagaggaggc gctaaggtgg ttcattccgt agacagttcg gcgaaagcga tttctttgac
     1981 gaaaaagaat gtcgagttga atttcccggg agatccccgt catgaggcat atgcggaaga
     2041 tgcgtttaag tatttggaaa aaatgggaag taattatgat ttaatcatat tggaccctcc
     2101 tgcgttcgct aaacataaga atgtactacg taacgcctta caagggtatc gcaaattaaa
     2161 tgcgatcgct ttcgagaaga tcaagccggg aggaatcttg tttactttct cttgttctca
     2221 agtagttagt aaagataatt tccgtttagc cgtatttagc gctgccgccc aatccggccg
     2281 tagtgtccga atcttacatc aattaaccca acccgcagat catccggtga atatctacca
     2341 tccggaaggg gaatatctga aaggtttagt attgtatgta gaataagata tgctctttgg
     2401 gtgaaaacaa agaattagtt ttcacccaaa attcaagtta ataccccgga ttctgtgtca
     2461 agttcggatt caaggaacgg actttatcgg gaatggggaa aacagtggta tagccattcg
     2521 attcatgggg caattgaggg cgatccgtat aagggcgggt aaactttcca aaacgcacca
     2581 aatcctgcct cctccagcct tcccaagcca attccagttg acgctcagcc aaaatatttt
     2641 ctaatgtcgc cttacgaggt aacattccca cacggaaacg aacggcattc aactcttcat
     2701 ccccattctc tccattacga actttcgctt ccgatctcat taacaagaca tccgcataac
     2761 ggaataatac gatatcatta tccgatagct ttccatcttt cgtccccatc ttatcgatct
     2821 cgtatttctt catgcgggca cccgccgttt tctcggcagg caacctagac aaatccaacc
     2881 taacctctag aggtaaatac accaaaggag tcccattatc taaccgaatc gtatcaccat
     2941 tgaggtcaaa catcgtatcg gcgtaataat tctcataaaa tcgggtatcg accgagtccg
     3001 tcccatacgc aaatacccga agggcctcta tcgtagcgca agagccgttc tctcccccca
     3061 atccatatgc tttggcatga ttatagtgac gggagcggaa aagatattgc atttggttcg
     3121 tatataagtt cttatccatc ggaatcgtga agatattctc tccggacgat tcattaaata
     3181 cagaaaaatt atccgcatag ttcagagata agctatagtt taagtctgtt attgaatcac
     3241 agtacgccac aaccgtttgc caagcgttca acttcctctc gcctacccta aaatagattt
     3301 cccgtccatt cggacgcaga ccatccgtcc agtcgttatc cgtaaacact tctgcgttta
     3361 aggccaactt cgccaataag aaataaacaa ccggtctcgt aattcttcca taataatcgc
     3421 cgggcgaatt actatgcgcc gtactcaata acaaaaggga ttcttgtaat tcttttacaa
     3481 caaaatcaaa gacctctttc cggtcactct gccgcacgtc tttcaccgga atggaagaag
     3541 aaacgataag agggacacgg ccaaacatat cgactaaata ataataatac atcgcacgaa
     3601 aagcacgaac ctccgcctca taccgatcta aatcgttata atccgttttt tgccgcaact
     3661 cgcctaatat ctctaaagat tgattgctta atacgattac tttatacaga tattcccaag
     3721 tagcttggat agcgtcacta ttcgttcccc acttatgcaa gaagagacct tgccagaaac
     3781 cgccgtcata ccagtcgccg ccacgagtcg ggagcatggc ctcgtcagtc gtaaaggtat
     3841 tcaagtcgta gacaccccgg tacgttccct gcaatccttg gctatcgcta taacctccga
     3901 tataattata taaggaagca accgtattca gatagacatt ctgaggggta tcgtacgcat
     3961 cctccggata aagctgatca cgagggtcct ctttcagata gccatcgcac gacgataaca
     4021 tcaaacccgc aaatatatag gataaaatag aaagctttct catacgaaca cctttttaaa
     4081 aattaaaact caaccccatc gtataggaac gaaccaccgg ataagatcgc ttatcgtcta
     4141 tacctaaggt attatttacg atagagctat ttatcatcgg agtcaatccc gaataacctg
     4201 taattgtcgc caaattattt acggaaaccg aaagccgtac gtttcttaca tatttcctta
     4261 aattaccaag agacacgttc caacccaacg tcaaataatc aaaattgata taatcccctt
     4321 tctccaacca ataatccgta gccgtctgat cttggatatt ccgggatggg gcttctcgca
     4381 acacgttata atccgggaat atatccatat tcatataagt tagcgatgtt ccattataaa
     4441 tcttatgccc aaaggctccg ttaatctgta ctgatagatc gaattgttta taccggaaac
     4501 tgatattaga gcctaaaagt gttttcggca tagcttgtcc cgcaatataa cgatcctcac
     4561 catcctccaa actcaccccg tttccattca agtcctcaat ctcatactta tagccgccgt
     4621 tcccatcgga aaccaaacct gtacatttcg gtaaataaaa aacacccaaa ggctgtccga
     4681 ccatttgata aacgatatga ttataccctc catggaaacc agccccattt aaatccgaga
     4741 tactagtata ttccggggcg gacatatatt cccctttata gtaaccgctc aaggagagca
     4801 atttattccg ttggaaagtt acgtttacgt ttatattcaa ttccatatct ttcgtacgca
     4861 agggcgtgac gccaataccc aattccacgc cactatttcg catcgatccc agattcgcca
     4921 acattttatt ataagcgaaa ggcggaacgc ttacatcgta taaatacaac atatcatccg
     4981 tcttggaatt ataataatct acggcaagaa taaaacgatt gtcgaaaaac ccggcatcga
     5041 taccggcatt gaacgtacgt ttcacctccc atttcaagtc cggattcgca ttacggatcg
     5101 tacccaaggt aacggtgggc gcaccattta cggaaacaac cccattaggt ttcatcaatc
     5161 gcaaagaatt gtaagaatcg atcgcgtctt gattaccgga taggccatat cccgaacgaa
     5221 tctttaaatt ccttacccac gagacacctt ccataaactc ctcttcggtc aacacccaag
     5281 cgacagaagc cgaagggaaa aaaccccatt tattattggc ccccactttc gaagaggcat
     5341 ccgcacgggc attcacggta gcgatatact ttccatcata aatataattc acacgtccaa
     5401 ggaaagaagc cagatgagga gcctcatagt aagaaccggt cccctcccat aaacgtaccg
     5461 cacctgcctg taaattatca taaccaaaac gatcggtact gaaattcgtc gcagtcgtat
     5521 aaaaacctct cgttatcatt ttctgagctt ccgccaatcc caatacattt agttgatgca
     5581 aaccaaagtc ttttttatag gccaacatga aatctcccag taaagattct gttttccgct
     5641 ccccccgata agcctgccca tgtgcccaaa ccgaagtagg gaggtattgg gcgttatcta
     5701 ttacattata ggtatacgaa ccgaaagccg taaacattaa atgcttactc aagttaaaaa
     5761 ccagttttaa gtgcgtattt atatgagcat tcgaatcatc atccttcacc tccaaccaag
     5821 ccaaaggatt cgtgatctgg ctagcgttgg ttatttgatc ccagctaccc gtctccatat
     5881 tcttatgatt cggaaatgtc gggttgaaag tagcggcaga atagaacatc ttctgtacat
     5941 catttaaata agcatttttc agcaaggaac caaatatgcc taaatcaaag accagaagat
     6001 cattgaacgc atgctgcgta atattcaact tggtcgtaaa attacgtgag ttcgtatttc
     6061 ggataacccc ttccctttcc acaaatccca aggaggcacg ataactggaa gtctccgaac
     6121 cacccccaaa agcgatatga tgattctgca ccagccccaa ccgggtaatc tcatcctgaa
     6181 agtccgtatt attccctaaa tctaaaatac cgatattacg ttcctccgcc agtttccgga
     6241 aaccattcgc cgataacata tccaaacttt tataagccgc ctccacaccg aaactcccat
     6301 cataactgat actaaaagct ccctgccgcc ctttctttgt cgttacctcg ataacaccgg
     6361 aagcaccacg agaaccatat tgagcagtct cagaggcatc tttcaagatc gtgaagttct
     6421 cgatatccgc cggatagatc gagctaagca aattaagatc ggcaaaaacc ccatcaataa
     6481 tcaccaacgg atcattacct cccgttaagg aagttgtacc ccggacccgg acggcagcca
     6541 aggcagcggc gctatttcct ccaaccggga tactaacgcc ggacaccctt cccctaagag
     6601 cgtccaaggg tgtagagatc aatccctcat tcatcccccc ttcattcacc cggtttacag
     6661 aaccggataa agtactgcga ttgcccgtag catatccgac agtgatcaac tcatctatca
     6721 aattggagtc cgacaagaga ggcttgatcg tatccggcag aagcggcagc tcctgaccgt
     6781 agccgtaaga gaaagacaag gccccgcaga gaaacaaaaa aaggactttt cggatatata
     6841 taagaacttt cataagtacg ttggatttaa gattaataac ccatataaat aaaacttccc
     6901 tcggttaagt tttgttcgca cccaagatac aacatttcct caagatctta aaaataaaag
     6961 cgtaccaagt tgtcaagaag cctcgacaag gctttagcga tatttaataa tgtccctcaa
     7021 aaatatatac ggaaatattt ctttattccg taatagattg tacctttgcc atcgttaaaa
     7081 aacatagcgt attattaagt aataacatac taaaacttat ttattatgtc aaaagtaaca
     7141 gttgttggtg ccggaaatgt aggcgctact tgcgcaaatg ttcttgcctt caatgaagtg
     7201 gcagacgaag ttgtaatgct agacgtaaag gaaggcgtat ccgaaggtaa agcgatggat
     7261 atgatgcaga ccgctcaatt gctaggtttc gatactaagg ttgtaggttg cacaaacgat
     7321 tatgagaaga cagctaactc tgacgttgta gttatcactt ctggtattcc tcgtaaaccg
     7381 ggtatgactc gcgaagaact gatcggtgtt aacgctggta tcgttaagag cgtagctcaa
     7441 aacatcttga aatactctcc gaacgcaatc ttggtagtta tctctaaccc gatggataca
     7501 atgacttatt tgtcattgaa gtctttaggc ttgccgaaga accgtatcat cggtatgggt
     7561 ggtgctttgg atagctctcg tttcaaatat ttcttatctc aggctctagg ctgtaacgct
     7621 aacgaggttg agggtatggt aatcggtggt cacggtgaca ctacaatgat tccgttggct
     7681 cgcttggcta cttacaaagg tatccctgtt agcaaattgt taagcgcaga gaaattgcaa
     7741 gaggttgttg cttccacaat ggttggtggc gctacattaa ctaaattgtt aggtacttct
     7801 gcttggtatg caccgggtgc tgctggagca tttgttgttg agtctatcat tcacaaccaa
     7861 ggtaagatgg ttccttgctc tgtttacttg gaaggtgagt acggtgaatc tgatctttgc
     7921 atcggtgttc ctgttatcct tggcaagaac ggtatcgaga agatcgttga gttggaattg
     7981 acagctgaag agaaagagtt gttcgctaag agcgctgccg ctgttcataa gactaacgag
     8041 gctttgaaag aagtgggtgc actttaattt gaatttctat taaagcgata aaagaggctg
     8101 atccttcggg gtt
//
LOCUS       DBMDTB010000139         8012 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_2432_length_8012_cov_10.476678, whole genome shotgun sequence.
ACCESSION   DBMDTB010000139 DBMDTB010000000
VERSION     DBMDTB010000139.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 8012)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 8012)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8012
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2432_length_8012_cov_10.476678"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..744
                     /locus_tag="ACZPB4_15495"
     CDS             <1..744
                     /locus_tag="ACZPB4_15495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1848 family protein"
                     /protein_id="HIR1099658.1"
                     /translation="SEGFEPNVPSVTQRVETFRELSEMIGKERVIWRFDPLIITPSIT
                     PRVLLSRIWKIGNQLKGYTDKLVFSFVDVKAYRKVQNNLIKETNCFTKEDVETAEMNA
                     MQRQETVEGLVKLREIWASTGWNVTLATCAEDIDLTVYGIEHNRCIDGDLMERVFGKD
                     YELVYYLRTGQLPEPDLFGTFPALPDKRKDLKDKGQRKACGCMISKDIGRYNTCRHFC
                     VYCYANTSRECVQKNAVHYSDDSESLIRS"
     gene            899..1912
                     /locus_tag="ACZPB4_15500"
     CDS             899..1912
                     /locus_tag="ACZPB4_15500"
                     /EC_number="3.1.30.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HIR1099659.1"
                     /translation="MAKKKGKPQPRKSKKKRASSFMSSVKKMLLGVFAVVVCFIGVLF
                     IYNWFYPVSKTRLVEKKQDRAEAIVRPKISDKGGSGTSGKKAAQATKNKQTTNPKKET
                     SAYTFQGGAEIPRLKNKQKEQVIKHEGYAVSYNSDYKIANWVAYELTSKEATSKKNER
                     SNKFVSDPMVKGATATNEDYTRSGYDRGHMAPAGDMKWSAKAMRESFYLSNICPQKPG
                     LNRGIWKDLEEQARLWAKENGSLLIVTGPVITDDLKRLGKNRVGIPKTFYKVICTITN
                     GKPEGVGFLFDNKDYGKTPLKSMMIPIDSVEKVTGIDFFPSLPDSIENPMEAYVNDGS
                     WSF"
     gene            2006..3055
                     /locus_tag="ACZPB4_15505"
     CDS             2006..3055
                     /locus_tag="ACZPB4_15505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008771968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HIR1099660.1"
                     /translation="MKGKLIPVFVLAALVSCSQPPVKEQGPRPVKLADVTSLNMVEKS
                     FSGVVSPDQFSDLAFKMSGPLISLNVDEGQKVRTGQIVAEIDPLDFKWEYEAKKASFQ
                     TAEAQLQRAKKLLSKQAISKQEYESTEASYSNAKAAFEYAQNTLNQTKLRAPFDGFIQ
                     KKYVENYQKVQAGQGIVCLINPNKLQVVFTMPESNINYFSSPYSVYVEFDNYKGVRFK
                     AKVKEYVEASPDGSGVPVYLYIDDPNFNLEKYKVAVGFSCRVILNVDSESFTQGAVLV
                     PLAAVVADDANSDKYVFVYNGQSQKVERRKITESMLIGKDGVIVTDGLRPGEQVVSAG
                     ATRLVDGQQVKVLTD"
     gene            3066..6110
                     /locus_tag="ACZPB4_15510"
     CDS             3066..6110
                     /locus_tag="ACZPB4_15510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008771969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HIR1099661.1"
                     /translation="MNIPKYSLENQKIIYFFLAVMLIGGIYSFFKLPKKEDSPFVIKQ
                     AVLVTQYPGATPQEVEKLVTEPIEREIQAMSDVFQIKSESYFGMSKISIELQPTLSPD
                     YMPVKWDELRRKVANIQPRLPSGASSISVSDDFGDVFGIYYALTADEGYTYDDLRNWA
                     QKIKTELSPVPGVQKVYLFGEQTQVVNVKISIPKLANLGIDPNAIQQVMQTQNLLVNT
                     GDINTGNYQLRLRAEGTYKDIQDIRDQLIVTKSGGEVRLGDIATVERGYMDPPSNLMR
                     VDGKRAIGIGVATGSKDDVVAVGNAVADHLAEMEQLFPVGMDLKTIYPENKIADEANN
                     GFILNLIESLLIVIVIIFIVMGSRAGMLVGSSLLFSVGGTLLIMLIWGVGLNRTSLAA
                     FIIAMGMLVDNAIVVTDNAQVGIKRGLSRYQALIDGATKPQWALLGATFIAVCSFLPM
                     YLAPASVAEIVKPLFIVLAVSLGLSWVLALTQTTTFGNFILKEAKPGENKDPYDTKLY
                     HKFESVLGRLIKRRYVTISTVVATLFLSLFVMSIMPQSFFPIMSKPYFRADLIFPEGY
                     SIYDVETNVKKIEEEYLSKNENIKSYSFTLGGSPVRYYLASSSIGPKPNFANVLIETQ
                     DPEDAQAEEGKFYDYMVANYPNILTRSALFALSPVPDAAIEIGFIGDNVDTLVALTQR
                     AQEIARNYDQVMEVRNSWGNKVPVWKPLYSQEKGLRLGITRQQVAYSLRSATNGVPLG
                     EYREGDVFMPILLKDADKDSISLNDIKTLPVYSAKGRSVKVEQVIDDFSLDYEFNVVR
                     RFNREPCMLMQCEPKRGANTMAAFSHLWKEIQEKIQVPEGYKMTYFGEQSEQDKGNKA
                     IAANIPLMFGLIYVTLLFLFPKYYRKPVLIMAMLPLIFIGVVLGLLVFGKSLDFFAML
                     GLLGLIGMNIKNAIVLVDEIGLQLNAGLSPVNAVIEATKTRIVPVTMASGTTILGMLP
                     LLGDAMFAGMAATIMGGLFVSTILTIFVLPVTYCVFFKIKSE"
     gene            6116..7408
                     /locus_tag="ACZPB4_15515"
     CDS             6116..7408
                     /locus_tag="ACZPB4_15515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008771970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HIR1099662.1"
                     /translation="MRNKIIIGCLLLGALSAKAQDIRLSAVEYKERVLEYSRQIKQSS
                     EERIAMQHAIKAAKTGFFPSVDFSGSYQYRINKYDLDFGPGMSVEMDHNTYSLGATVS
                     QPIYAGGQIYNNYKAAQVQGKITEQAEELTTDNIVYSADLNYWTAAARKGMYDVMCQY
                     VDIVGELANVLTIRFNDGQISKTDLLQVESRLKEAELNKSSAYKEYQIALQNLNSLMG
                     VSPLDPIEVEDSITTYLALPLQVGEDVALRNRPDYAISELNIEYQKRQINLSKAKYNP
                     SLAIGFQGTWGTPMLNVKGSDQLWTPAVFASLKIPLFRWGARFKEVNSQKAILRSKEY
                     ALDNTRDKIAQEVANAWTSLTEYTKQITVAEEACKIAEENLDLNTFSYNEGKLPILDV
                     LSAQLSWIQSYSSLIQTWYQQKASLAQYNKAIGIRRLQ"
     gene            7597..>8012
                     /locus_tag="ACZPB4_15520"
     CDS             7597..>8012
                     /locus_tag="ACZPB4_15520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008771971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HIR1099663.1"
                     /translation="MYTKLLDKQTKLALIGLGYVGLPIAMEFAKHVSVIGFDINEDRL
                     DKLRNGIDPCGELSSEVFEHKDITFTSSIEKLREASFYVIAVPTPIDSHNEPDLSPLL
                     GATRTVGKVLKRGDYVVYESTVYPGCTEEDCIPILE"
BASE COUNT         2139 a         1585 c         2139 g         2149 t
ORIGIN      
        1 agcgaaggct ttgagccgaa tgtgccgagc gttacgcaac gggtggagac atttcgggag
       61 ttgtcggaaa tgatagggaa ggaacgggtg atctggcgat tcgacccatt gattataact
      121 ccatctatca cgcctcgtgt cctgcttagc cgtatttgga agatcggcaa tcagttgaaa
      181 ggatatactg ataagctcgt gttcagtttc gtagatgtaa aggcgtatcg taaggtacag
      241 aacaatctta taaaagagac gaattgcttt acgaaagagg atgtggaaac cgctgagatg
      301 aatgcgatgc aacgtcaaga aactgtagag ggattggtga agttgaggga aatttgggct
      361 tctactggtt ggaatgtgac actcgctact tgtgccgagg atattgacct tacggtttat
      421 ggcattgagc ataaccggtg tatcgacggt gatttaatgg agcgtgtgtt tgggaaggat
      481 tatgaattgg tttattatct tcgaacaggc caattaccag aaccggatct ttttggtacg
      541 tttcccgctt tacccgacaa acgcaaagac ctaaaagaca aaggccaacg gaaagcctgt
      601 ggttgcatga taagcaaaga tatcggtagg tataacactt gccgccattt ctgtgtctat
      661 tgttatgcca atacaagtag ggaatgcgta caaaagaatg cggtacacta ttcggacgat
      721 agtgaaagtt tgattcgaag ttagatttga aagcaaggtc aaatgaagcg gcgtattaaa
      781 ttaagccgtc ttttatagta atcgagacca atactatcct agaatagtgt tgtataacat
      841 gccggattta tctatttttg cgcccaatac gaaaggttaa gaataggaag ttttaggtat
      901 ggcaaaaaag aaaggtaagc ctcaaccccg gaaaagcaag aagaagcggg catcatcatt
      961 catgtcctct gtaaagaaga tgcttcttgg cgtttttgcg gtagttgttt gttttatcgg
     1021 tgtattattc atatataact ggttttatcc ggtatccaag acacggcttg tagagaagaa
     1081 acaggatcgg gcggaggcaa tagtccgtcc gaagatctcg gacaagggcg gctccggaac
     1141 atcgggtaag aaagccgcac aagcgacgaa aaacaagcaa acgacgaacc caaagaaaga
     1201 gacctccgct tatacttttc aagggggagc tgagataccg agactaaaga ataaacaaaa
     1261 agagcaggtt ataaagcatg agggctatgc ggtttcttat aattccgatt ataagatcgc
     1321 caattgggta gcctatgaac tgacctcgaa agaggcgaca agtaagaaga acgagcggtc
     1381 taataagttc gtctcggacc ccatggtgaa aggggctacc gccacgaacg aggactatac
     1441 ccgttccggc tatgaccggg gacatatggc gcctgccggc gatatgaaat ggtccgccaa
     1501 ggccatgcgg gaatcgttct acctaagtaa tatctgtccg caaaagcccg gcttgaaccg
     1561 gggtatctgg aaagatctgg aagaacaggc tcgtttgtgg gcgaaagaga atggctcttt
     1621 gttgatcgtg accggcccgg tgatcacgga cgacctgaaa cgattaggta agaatcgggt
     1681 gggaatcccg aagacctttt ataaggtaat ctgtacgata acgaacggta aaccggaagg
     1741 ggtaggtttt ctgtttgata ataaagacta tggaaagact ccgttgaaat cgatgatgat
     1801 ccctatcgat agcgttgaga aggttaccgg aattgacttt ttcccttctt tgcctgattc
     1861 gatagaaaat ccgatggaag catacgtgaa tgatggtagt tggtcttttt aaggcacgtt
     1921 atgctcaaca atctctaggc gagaatgttt tatatttact gtgaagaaaa agaaatcata
     1981 attaaataac aaaatgcaag ttatcatgaa aggaaaatta atccctgtgt ttgttttggc
     2041 agcattggtt tcctgtagtc aaccacccgt taaggagcaa ggtcctcgtc cagttaaatt
     2101 ggcggacgtt acttcgctga acatggttga gaaatcattc agtggagtgg tatcgcccga
     2161 tcaattcagt gatttggcgt ttaagatgtc cggcccgctg atctcattaa acgtggatga
     2221 aggccagaag gtccgtacgg gacagatcgt ggccgagatc gatccgctgg actttaaatg
     2281 ggaatatgag gcgaagaaag cgtctttcca gaccgctgag gcgcaattgc aacgtgcgaa
     2341 gaagttattg tccaagcaag ctatctccaa gcaagagtat gagtctacgg aagcctctta
     2401 ctcaaatgcc aaggcggctt tcgagtatgc gcaaaacaca ttgaaccaga caaagcttcg
     2461 tgcgccgttc gatggattta tccagaagaa atatgtggag aattaccaga aggtacaggc
     2521 cggacaagga atcgtttgct tgatcaaccc gaataagtta caggtcgtgt ttacgatgcc
     2581 ggagagtaat atcaattact tctcttctcc ttattctgtt tatgtggaat tcgataatta
     2641 caagggcgtt cgcttcaagg cgaaggtgaa agaatacgtg gaagcctctc cggatggttc
     2701 cggcgttccc gtatatctgt atatcgacga tccgaacttt aatttagaga aatataaggt
     2761 agccgtaggt ttctcttgcc gtgtgatctt gaacgtggat agcgagagtt tcacgcaagg
     2821 cgccgtattg gttccgctag ccgctgtcgt ggctgacgat gccaatagcg ataagtatgt
     2881 gtttgtttat aatgggcagt ctcaaaaggt tgagcgtcgc aagattaccg agtctatgct
     2941 gatcggcaag gatggcgtga tcgtaacgga tggcttgcga cccggcgaac aggttgtctc
     3001 agccggagcc actcgtttgg tggatggaca acaggtaaaa gtattaacag attaagagat
     3061 aaacaatgaa tattccaaaa tattccttag agaatcagaa gattatatac tttttcctag
     3121 cggtcatgct gataggaggt atatattctt tctttaaatt gccgaagaag gaagattctc
     3181 ccttcgtaat caagcaagcg gttttggtta cccaatatcc gggagcgaca cctcaggagg
     3241 tggagaagct ggtgactgag ccgatcgaac gggagattca ggctatgtcg gatgtgttcc
     3301 agatcaaatc tgagtcttat ttcggtatgt ccaagatttc tattgagttg cagcctacct
     3361 tgtctccgga ttatatgccg gtcaagtggg acgagttgcg tcgtaaggtg gcgaatatac
     3421 agccccgcct tccgtctggc gcctcctcga tatccgttag tgatgacttc ggtgacgtat
     3481 tcggaattta ttatgccttg acggccgatg agggatatac ttacgacgac ctgcgtaatt
     3541 gggcgcaaaa gatcaagacg gagctatctc ctgtaccggg tgtacagaag gtctacctat
     3601 tcggtgaaca gacacaagtt gtcaacgtaa agatctctat cccgaaactg gctaacctag
     3661 gtatcgaccc gaacgctatc cagcaggtga tgcaaacgca gaacttgttg gtgaatacgg
     3721 gagatatcaa taccggtaat tatcaattgc gtttgcgtgc ggaaggtacg tataaggata
     3781 tacaagatat ccgggaccaa ttgatcgtga cgaaaagtgg cggtgaggtt cgtttgggag
     3841 atatcgctac ggtagagcgt ggttatatgg accctccctc gaacctgatg cgtgtggacg
     3901 gtaagcgtgc catcggtatc ggtgtcgcta ccggttcgaa agacgatgtg gttgccgtgg
     3961 gtaacgccgt ggcggatcat ttagcggaga tggagcagct gttcccggtg ggtatggacc
     4021 tgaaaacgat ttatccggag aacaagatcg cggatgaggc gaacaacggt tttatcttga
     4081 acttgatcga gtcgttgttg atcgttatcg tgattatctt tatcgtgatg gggtcccgtg
     4141 ccggtatgtt ggtcggtagt tcgttgttgt tctcggtagg tggtacctta ttgatcatgt
     4201 tgatctgggg tgtcggcttg aaccgaacct cgttggcggc ctttattatc gctatgggta
     4261 tgttggtgga taacgctatc gtggtgacgg ataatgccca agtcggtatc aagcggggac
     4321 tttcccgtta tcaggcgttg atcgatggcg cgacgaaacc gcagtgggcg ttgttgggcg
     4381 ctacctttat cgccgtatgt tctttcttgc cgatgtactt ggcaccggca tccgtggccg
     4441 agattgtgaa accgttgttt atcgtattgg cggtatcctt gggattaagc tgggtcttgg
     4501 ccttgacgca aacgactacc ttcggtaatt ttattttgaa agaggcgaaa ccgggtgaga
     4561 acaaagaccc gtacgatacg aagctgtacc ataaatttga gtcggtattg ggccgtttga
     4621 tcaagcgtag atatgtaacg atctctaccg tggtagctac gttattcctt tccttgttcg
     4681 tgatgagcat catgccgcag agtttcttcc cgatcatgag caagccttat ttccgtgcgg
     4741 acttgatctt cccggaagga tatagcatct acgacgtgga gacgaatgtg aagaagatag
     4801 aagaggaata tctcagcaag aatgagaata tcaaatcata ctcgtttacc ttgggaggtt
     4861 cgccggtacg ttattacttg gccagttctt ctatcggccc gaagccaaac ttcgccaatg
     4921 tgttgatcga gacacaagat ccggaggatg cgcaagcgga agagggtaag ttctacgatt
     4981 atatggtcgc taactatccg aatatattga cccgttcggc tttgttcgcc ttgtctccgg
     5041 ttccggatgc ggcgatcgag atcggtttta tcggcgataa cgtagacacg ttggttgcct
     5101 tgacgcaaag ggcgcaggag atcgcccgga attatgatca ggtgatggag gttcgcaata
     5161 gttggggtaa caaggttccg gtatggaagc cgctatattc ccaagagaaa ggtttgcgtc
     5221 tgggtattac ccgtcaacag gtggcttatt ccttgcgttc ggctacgaat ggcgtacctt
     5281 tgggtgagta tcgtgagggc gatgtgttta tgccgatctt actgaaagat gcggataagg
     5341 attctatcag tctgaatgat ataaagactt tgccggttta tagtgctaaa ggccgttcgg
     5401 taaaagtgga gcaggtgatc gatgatttct cgctggatta tgagtttaac gtagtgagac
     5461 gattcaatcg tgagccgtgt atgcttatgc agtgtgagcc gaagcgtggc gccaatacga
     5521 tggctgcttt cagtcatttg tggaaagaga tacaggagaa gattcaggtg ccggaaggat
     5581 ataagatgac gtatttcggt gagcaatccg agcaagataa aggtaataag gcgatcgccg
     5641 ctaatatccc gttgatgttc ggtttgattt atgtcacctt gttattctta ttcccgaaat
     5701 attaccggaa accggtattg atcatggcga tgctgccgtt gatcttcatt ggtgtggtat
     5761 tgggattgtt ggtgttcggt aagtctctcg acttctttgc tatgctgggt ctgttgggct
     5821 tgatcggtat gaatatcaag aatgcgatcg tgctggtgga cgagatcggt ttacaattga
     5881 acgcaggctt gtctccggtg aatgccgtga tagaggcaac gaaaacccgt atcgttccgg
     5941 tgacgatggc ttccggtacg acgatcttag gtatgttgcc gttgttgggt gacgctatgt
     6001 tcgccggtat ggcggctacc atcatgggtg gtctgttcgt atctacgatc ttgacgatct
     6061 tcgtgcttcc ggttacttat tgtgttttct ttaagattaa atcagagtaa aaggtatgag
     6121 aaataaaata atcataggtt gtttattgtt gggtgccttg tccgctaaag cgcaagacat
     6181 ccggctatcg gctgtggaat ataaggaacg ggtccttgaa tacagccgtc agatcaagca
     6241 aagctctgag gagcgtatcg ctatgcagca tgcgatcaag gccgctaaga ccggtttctt
     6301 cccttcggta gacttctccg gcagttatca gtatcgtatc aataaatatg atttggattt
     6361 cggaccgggc atgtccgtag agatggacca taatacgtat agcctaggcg ctacggtgag
     6421 ccagcccatc tatgccggcg gacagatcta taataactat aaggcagctc aggtacaagg
     6481 caagatcacc gagcaagcag aagaattgac aacggataat atcgtttatt ccgccgattt
     6541 gaactattgg acggccgccg cacgtaaagg tatgtacgat gtgatgtgcc agtatgtaga
     6601 cattgtcggg gagttggcga acgtgttgac gatccgtttc aatgacggcc agatcagtaa
     6661 gaccgattta ttgcaagtgg agtcccgctt gaaagaagcg gaattgaata aaagctcggc
     6721 ttataaggaa tatcagatcg cgttacagaa cctgaactca ttgatgggtg tgtctccgtt
     6781 agacccgatc gaggtggaag attccattac gacctatctg gccttgccgt tgcaagtagg
     6841 agaggatgta gctcttcgga atcgtccgga ctacgctatt tccgagttga acatagagta
     6901 tcaaaagaga cagatcaatt tgtcgaaggc gaaatataac ccgtctttgg cgatcggttt
     6961 tcaaggtact tggggtacgc cgatgttgaa cgtgaaaggt tcggaccagt tgtggactcc
     7021 ggccgtcttc gcttccttga agataccttt gttccgttgg ggagcccgtt tcaaggaggt
     7081 aaattcccag aaggccatcc ttcgtagtaa ggaatacgcc ttggacaata cgcgtgataa
     7141 gatcgctcaa gaggtagcga acgcatggac aagcctaacc gagtatacga aacaaattac
     7201 cgtcgcagaa gaggcttgta agattgccga ggagaacctt gatttgaata ccttcagcta
     7261 caacgagggt aaactaccga tcttggatgt gctctccgcc caattgtcat ggattcagtc
     7321 ttacagtagc ttgatccaga cttggtatca gcaaaaggct tctttagccc aatataacaa
     7381 ggctataggt atccggcgtt tgcagtaaaa gaaacatatt tatacttaga agacaaggtc
     7441 ccttattttg gaaacgagat aagggacctt ctttatgaaa taaaacatcc tttattccgt
     7501 taggtaaact gaagattgct acatttgcat acaatctcgt ctgtttggga cactccttgg
     7561 aacccggact tttaagtaga atgatgaaat aataagatgt atacaaagtt actagataaa
     7621 caaacgaaac ttgccctaat cggactagga tatgtcgggc ttcctatcgc gatggaattc
     7681 gctaaacatg tttccgttat cggatttgat atcaacgagg atcgcttgga caagcttcgg
     7741 aacggtatag atccgtgtgg tgagctttcc tctgaggtat ttgaacataa ggacatcaca
     7801 tttacttctt ctatagagaa gctaagggag gcttcttttt acgtgatagc tgttcctacc
     7861 ccgatagaca gccataacga gccggatcta tcccctttgt tgggtgcgac tcgcacggta
     7921 ggcaaagtcc ttaaacgagg cgattatgta gtatacgaat ctaccgtata tccgggatgt
     7981 acggaagagg attgcatccc gatcttggag ga
//
LOCUS       DBMDTB010000140         7911 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_2475_length_7911_cov_10.734827, whole genome shotgun sequence.
ACCESSION   DBMDTB010000140 DBMDTB010000000
VERSION     DBMDTB010000140.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 7911)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 7911)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7911
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2475_length_7911_cov_10.734827"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..723)
                     /locus_tag="ACZPB4_15525"
     CDS             complement(<1..723)
                     /locus_tag="ACZPB4_15525"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099664.1"
                     /translation="MELEENKISISTIKQYLQLIIHDLGKFTHLEFLTLKGWLLYSLS
                     LVTILCIPCMAILIITGLISGNIPLDLLIAISLIPFIFILPLTLTLTFINNYKRPKTL
                     RKYILQGLGLYLWDSPPKKVSQTAFECIKEGKLFRIEVCLLKNEGKEDWFTCMIIPYY
                     IPKSIKDKEQHIENVNRYLSEKCIFEIKQDMAFFTIPVKVFPKLDLNKSIEELLYAMR
                     RFDLRTSTFYNPTAILNKVPNTL"
     gene            961..1665
                     /locus_tag="ACZPB4_15530"
     CDS             961..1665
                     /locus_tag="ACZPB4_15530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TapB family protein"
                     /protein_id="HIR1099665.1"
                     /translation="MKVKILYTALISLIAGGAMAQDCTFFFPQTEGTVWVRKGYDAKG
                     NLQSVMSYQVDEVETLPSGQEVEADYVYTNPSGTIVNKGDIKAYCQNGEFFLDSKETL
                     SYPGVVSEMNTNVDITENFINYPNPYAANFDKNNVYFDEASVKIYDKKNRKNRKDMAI
                     KDREFIKTESITTPAGTFDCAKVKYNIATRSPKSKETITGYGYEWYSPNVGLVRTEQY
                     DKNNVLQSYTVLEELK"
     gene            1816..2220
                     /locus_tag="ACZPB4_15535"
     CDS             1816..2220
                     /locus_tag="ACZPB4_15535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PH domain-containing protein"
                     /protein_id="HIR1099666.1"
                     /translation="MEREYKSKVGWWYHLVIIMVVIGCVAAFLRTNISAIVGMMIAAL
                     GVLHVFFNTYYRITEDDMLIAHCSIFPEKKIAIADIEALESTVMPVSSYALSLDRLII
                     WSNGKPWMLISPTNRADFIKQLRKINPNIQLK"
     gene            2231..3577
                     /gene="lpdA"
                     /locus_tag="ACZPB4_15540"
     CDS             2231..3577
                     /gene="lpdA"
                     /locus_tag="ACZPB4_15540"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     (NADH) activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HIR1099667.1"
                     /translation="MKYDVAIIGGGPAGYTAAERAAQGGLSTILFEKNALGGVCLNEG
                     CVPTKTLLYSAKTYDNIKHASKYAVKAENPSFDLPKIIARKNKVVKKLTAGIRMKMTE
                     HGVVMVTAEACIQGRAADGTITIAAGEELYEAANLLICTGSETVIPPIPGLAETEYWT
                     SREALQSKELPASLVIIGGGVIGMEFASFFNSLGVEVHVVEMLDKILGPMDRELSEML
                     QAEYAKRGIKFYLSHKVTGVHGTEVFVEKDGETFTLHGDKVLLSVGRRPVTKGFGLET
                     LAPETFRNGVKVNEYMQTSLPNVYACGDITAFSLLAHTAVSEAEVAVDHLLGKLRPMS
                     YKAIPGVVYTNPEIAGVGKTEEELQAEGISYTVKKIPMAFSGRFVAENEMGNGVCKLI
                     LSEDETLIGAHMLGNPASELIVIAGIAIEKGMKSDELKSFVFPHPTVGEIIKEALY"
     gene            3614..4339
                     /locus_tag="ACZPB4_15545"
     CDS             3614..4339
                     /locus_tag="ACZPB4_15545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4271 domain-containing protein"
                     /protein_id="HIR1099668.1"
                     /translation="MGTFEGYVGIRLWDGQLVDDVVFSLLFVLFMCFALVFRTNYRLF
                     LKMMRDVVYVKERQNLFEVTRGSEWLFRNFMTFQALFLCSVCLFAIARAYGYFNHLLE
                     NTVLISIGLIMMVLMLFYWCKRCFYYLLGVVFTDAPKYKFWKTNYNAIIGAWGICLYI
                     PALWLVFVGSSIQIPVLLFVFFYILCRFVIIYKTIRIFHRKNSSFLYISLYLCGQEIL
                     PLVFLYEGIIYLYNFIESSTLWH"
     gene            4336..5091
                     /locus_tag="ACZPB4_15550"
     CDS             4336..5091
                     /locus_tag="ACZPB4_15550"
                     /EC_number="4.2.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009318403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004852 - uroporphyrinogen-III synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006780 - uroporphyrinogen III biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006782 - protoporphyrinogen IX
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0033014 - tetrapyrrole biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III synthase"
                     /protein_id="HIR1099669.1"
                     /translation="MNIKKLLVSQPKPASEKSPYFDIAEKYGVEIDFRPFIKVEPLSS
                     KEFRQQRISVLDHTAVIFTARTAIDHFFHLCEELRVAIPETMKYFCMTEAIAVYLQKY
                     IVYRKRKIFYGQTGKADDLVTVIAKHAKEKYLVPVSDVHKDDLFALLDAKKINYTKAV
                     MFRTVSNDFAKDEKFDYDMLVFFSPSGISSLLKNFPDFKQDDIKIGCFGPTTAKAVKD
                     AGLRLDVEAPTVEAPSMTAALDLYLKKQQDGKK"
     gene            5091..5477
                     /gene="rnpA"
                     /locus_tag="ACZPB4_15555"
     CDS             5091..5477
                     /gene="rnpA"
                     /locus_tag="ACZPB4_15555"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009016771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HIR1099670.1"
                     /translation="MTTKRYTLSKEERLSWKRYIDLLFEKGQSFVAFPLRVVYLPMEE
                     EMPARASFLVSVPKKRFKRAVKRNLIKRQVREAYRVRKYDLLEPLEAKNKGMLIAFLY
                     LDKEIHPYAAMEKAMKKAIHILRDKE"
     gene            5477..5698
                     /gene="yidD"
                     /locus_tag="ACZPB4_15560"
     CDS             5477..5698
                     /gene="yidD"
                     /locus_tag="ACZPB4_15560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HIR1099671.1"
                     /translation="MRRFFTTLLLLPVYFYKYCISPMTPASCRYTPTCSEYAVQALKK
                     YGPVKGLYLAVKRILRCHPWGGSGYDPVP"
     gene            5682..6353
                     /locus_tag="ACZPB4_15565"
     CDS             5682..6353
                     /locus_tag="ACZPB4_15565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HIR1099672.1"
                     /translation="MIRFRNAMGYYDIHTHQMPFHKEDIAIINRIVSPMGDMQPGSLP
                     DTVIRSYGIHPWYIYNVKEQMDLLRVLVSGSGVVAIGEAGLDTLAESPMDLQKEVFLA
                     QANLAEETHKPLIIHCVKAWADLIACKKAVKPEMPWIIHGFRGNGELASQLVRLGFYL
                     SFGDRFNPSALRAAWPDFLFLETDDKSIDIRGVYQNVAEALDIPEEKLRIQIAKNVSI
                     FHLNG"
     gene            6457..7749
                     /gene="tyrS"
                     /locus_tag="ACZPB4_15570"
     CDS             6457..7749
                     /gene="tyrS"
                     /locus_tag="ACZPB4_15570"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010991893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HIR1099673.1"
                     /translation="MNFVEELRWRGMIADMMPGTEEQLQKELTSAYVGIDPTADSLHI
                     GHLVSVMMLKHFQRAGHRPIALVGGATGMIGDPSMKSAERNLLDEATLRHNQDCIKKQ
                     LAKFLDFDSDAPNAAKLVNNYDWMKGYSFLNFIRDIGKHITVNYMMAKDSVKKRLSRE
                     SSVGMSFTEFSYQLLQGYDYLYLYEHEGCRLQMGGTDQWGNITTGTELIRRTLGGEAY
                     ALTCPLITKADGGKFGKTESGNIWLDRRYTSPYKFYQFWLNVSDADAAKYIKIFTDLS
                     QEEIAALEAEQEAAPHLRPLQKRLAKEVTVMVHSLEDYEAAVEASNILFGNSTHEALL
                     KLDEDTLLAVFEGVPHFDISRDELAAGIKAVDLCTEKAAIFPSKGEMRKLVQSGGVSF
                     NKEKLAEVDTVIDCSSLLDDKYLLVQRGKKNYYLLIAK"
BASE COUNT         2169 a         1388 c         1964 g         2390 t
ORIGIN      
        1 gagggtgttt ggtactttat ttaatattgc ggtgggatta tagaatgtgg atgtacgcaa
       61 atcaaaacgt ctcatagcgt acaaaagttc ttcaatactt ttatttaggt ctaacttcgg
      121 aaagactttg actggtatgg tgaaaaaagc catgtcttgc tttatctcaa aaatacattt
      181 ctcgctcaga tagcgattca cattttcgat atgctgttct ttgtctttta ttgatttagg
      241 tatataataa ggaataatca tgcaagtgaa ccaatcttct tttccttcat tctttaaaag
      301 gcaaacctca attctgaaaa gttttccctc ttttatgcat tcgaatgctg tttggctgac
      361 ctttttgggt ggactatccc aaagatagag tcccaatcct tgaagtatgt attttcttaa
      421 tgtctttggt ctcttataat tgttgataaa agtcaatgtc aatgtcagag gtaaaataaa
      481 tatgaaggga atcaatgaga ttgcgatcag taggtccaat ggaatatttc cggatatgag
      541 acctgtaata attagaatag ccatacaagg tatacaaagg atagtcacta aagaaagtga
      601 atatagtaac catcctttca aggtcagaaa ctctagatga gtaaatttac ccaaatcatg
      661 tattattaat tgtaggtatt gtttgattgt agagattgat atcttatttt cttccagttc
      721 cattatgctt gtttaatgtc tatattaatt acaaaattac aacatatcct ttataaactg
      781 gtatatttca tgtaaatatg taatagatta cttcatagtt atggttaaat gtattgtcaa
      841 gaaagatatt ttggctattt ttaattttca ccttctgaac atttagtggt tcactctgtt
      901 ctaacaaagc attggatatc cggcatgtat ttagtagtga attaattaaa cgtcaaaatt
      961 atgaaggtga aaatattata cacggcttta atctcattga tcgcgggagg agcgatggcg
     1021 caagattgta cgttcttctt tccgcaaaca gagggaacgg tatgggtccg taaaggatat
     1081 gacgcaaagg gaaacttaca atctgttatg agttatcaag tggatgaggt ggaaacattg
     1141 ccttccggcc aagaggtgga agcggactac gtatatacta atccctccgg tacgatcgtg
     1201 aacaaaggag atatcaaggc atactgccag aatggagaat ttttcctcga ctcgaaagag
     1261 acgctctctt atccgggagt ggtatcggaa atgaatacga atgtggatat cacggagaac
     1321 tttataaatt acccaaatcc gtatgcggct aatttcgata agaataacgt gtatttcgac
     1381 gaggcttccg taaagatcta cgataagaag aaccggaaga atcgtaagga tatggccatt
     1441 aaggaccgtg agtttattaa aacggaaagc ataacaactc ctgccggtac gttcgattgc
     1501 gctaaggtaa aatataatat cgctacacgt tcccctaaat caaaggagac aatcactggg
     1561 tatggctatg agtggtacag cccgaatgta ggcttagtgc gtacggaaca atatgataag
     1621 aataacgtat tacaatccta tacggtattg gaagaattaa aataaaaagg cgactacaat
     1681 cttatgattt gtattaaccg gtttaagtgg atacgctgtt gctgagaagt gacagcgtat
     1741 tttcttttat gggaaagatt gggcaatttt ctttttgttt gacgtttttc gttaacttgc
     1801 ggcaaatttc ggaaaatgga aagagaatat aaatcaaaag tgggatggtg gtatcatttg
     1861 gtgattatca tggtggtaat cggttgcgtg gctgcgtttt tgcgtaccaa tatatcggct
     1921 atagtgggta tgatgatcgc tgcgttgggg gtgcttcatg ttttctttaa tacgtattac
     1981 cggataacgg aagatgatat gttgatagcg cattgtagta ttttcccgga gaagaagatc
     2041 gctatcgctg atatagaggc gttggaatct accgtgatgc cggtgtccag ctacgccctt
     2101 tcgttggatc ggctgatcat atggagcaat gggaaacctt ggatgctcat atctccgacc
     2161 aaccgggctg attttatcaa acaattgaga aagattaatc ctaatataca acttaaatag
     2221 atctaatagt atgaaatacg atgtcgctat aatcggtgga ggtcctgccg gttatactgc
     2281 cgcggagaga gcggcgcagg gtgggctttc cacgattctt tttgagaaaa acgcattggg
     2341 cggggtttgt ttgaatgagg gatgtgtgcc gacaaagacg cttctttatt ccgctaagac
     2401 gtatgataat atcaagcatg cttccaagta tgcggtgaaa gcggagaatc cttcttttga
     2461 tctcccgaaa atcatcgccc gtaagaataa ggtcgtgaaa aagctgacag ccggtatccg
     2521 tatgaaaatg acggagcatg gcgtggtgat ggttacggcg gaagcttgta tccaagggcg
     2581 tgcggccgac gggacgatta cgatcgccgc cggagaagag ctatacgagg ctgcgaacct
     2641 tttgatctgt acgggatcag aaacggtaat tcctcctata cccggattgg cggagacgga
     2701 atattggacg agccgggagg cgttgcaatc gaaggagctt ccggcctctt tggtgataat
     2761 cggtggaggc gtgatcggta tggagttcgc ttctttcttc aatagccttg gggtagaggt
     2821 acatgtcgtg gagatgttgg ataagatatt aggcccgatg gatcgtgagc tgtccgaaat
     2881 gttgcaagcg gaatacgcta aacgggggat taagttctat ctaagtcata aagtgaccgg
     2941 ggtgcatgga accgaggttt ttgtagagaa agacggggag acattcacgt tgcatggcga
     3001 taaggtcctt ttgagtgtag ggcgtcgtcc ggttacgaaa ggttttggct tggagacact
     3061 ggctccggag acttttcgta atggggtgaa ggtgaatgag tacatgcaga cttccctgcc
     3121 aaatgtatat gcttgcggtg atattaccgc tttctcctta ctggcgcata cggcagttag
     3181 cgaggcggag gtggccgtgg atcatctctt gggcaaattg cgcccgatga gttataaggc
     3241 tattccgggt gtcgtttata cgaatccgga gatcgccggt gtcgggaaga cagaggagga
     3301 gttgcaggca gaaggtattt cgtataccgt gaagaaaata ccgatggcat tctctgggcg
     3361 ttttgtcgcg gagaatgaga tggggaatgg tgtttgtaag ttgatcttgt cggaggatga
     3421 gacgttgatc ggtgcccata tgttgggtaa tccggcctcg gagttgatcg tgatcgccgg
     3481 aatcgctatt gagaagggga tgaaatcgga tgagttaaag tcgtttgtgt tcccgcatcc
     3541 tacggtagga gagattatta aggaagcgct ttattgaaat aattatgtac ctttgtgccg
     3601 ataatagcgg cacatgggta catttgaagg atatgtaggg attcgtttgt gggacggaca
     3661 attggtggac gatgtggtct ttagcctttt gttcgtctta tttatgtgtt ttgcgttggt
     3721 gttccgtacc aattatcgtt tattcctgaa gatgatgcgt gatgtggtat atgtgaaaga
     3781 acgtcaaaat ttatttgagg taacgagggg gagcgaatgg ctcttccgga atttcatgac
     3841 gtttcaagcc ttgtttcttt gtagcgtttg cctttttgct atcgctaggg catatgggta
     3901 tttcaaccat ttgctagaaa atacggtatt gatatctatt gggttgataa tgatggtatt
     3961 gatgctgttt tattggtgta agcgctgttt ctattattta ttgggggttg tttttacgga
     4021 cgctccgaaa tacaagtttt ggaagactaa ttataacgct attataggag cgtgggggat
     4081 ctgtttatac attccggcac tttggttggt attcgtgggg agcagtatac aaattcctgt
     4141 tttgttgttt gtatttttct atattctgtg tcgttttgtg ataatttata agaccatacg
     4201 gatatttcac aggaaaaata gcagtttttt atatattagt ttgtaccttt gcggccaaga
     4261 aatattgcct ttagtttttc tgtatgaagg cattatttat ttgtataact ttatcgagtc
     4321 aagtactcta tggcattgaa tattaaaaaa ttattggtat cacaaccgaa gcctgcatcg
     4381 gagaaatcac catatttcga tattgcagaa aaatacggtg tggaaataga tttccgcccg
     4441 ttcatcaagg ttgaaccttt atcttccaag gagttcaggc agcaacgaat ctcggttttg
     4501 gatcataccg ccgttatttt tacggctcgt acggctatcg atcatttctt tcatttatgc
     4561 gaggaattgc gtgtggctat cccggaaacg atgaagtatt tctgtatgac agaggcgatc
     4621 gctgtttatc tccagaagta tatcgtttat agaaaacgta agatttttta tggtcagacc
     4681 ggtaaggcag atgatttggt gactgttatc gccaaacatg cgaaggagaa atacctagta
     4741 cctgtttccg atgtacataa agatgatcta ttcgctttgt tagacgcgaa gaaaatcaac
     4801 tatacgaaag cggtgatgtt ccgtacggtg agcaatgatt tcgcgaagga cgagaaattc
     4861 gattatgata tgttggtttt ctttagtccg tcgggtatct cttccttatt gaagaacttc
     4921 ccggatttca aacaagacga tataaagatc ggctgttttg gccctactac ggcaaaggct
     4981 gttaaagatg cgggtctgcg tttggacgtt gaggctccca cggtggaagc cccttctatg
     5041 actgctgctt tggatttata tctgaaaaaa cagcaagacg gtaaaaaata atgacgacaa
     5101 aaaggtatac cctttcaaaa gaagaacgcc tgtcgtggaa acgttacatt gacctattat
     5161 tcgaaaaagg acaatcgttc gtggcgtttc cactgcgggt cgtttattta ccgatggagg
     5221 aagagatgcc tgcccgtgct tccttcttag tgagtgtacc gaagaaaaga tttaagagag
     5281 ccgtaaaacg taacttgatc aaacgacagg tacgtgaggc ttaccgggtt cgtaaatatg
     5341 atttactgga accgttggaa gcgaagaata agggcatgtt aatcgctttc ctgtacctcg
     5401 ataaagagat ccatccgtac gctgcgatgg aaaaggcaat gaagaaagcg atccatatcc
     5461 ttcgggataa agaataatga gacgcttttt taccacatta ctcttattgc cggtttattt
     5521 ctacaaatat tgtatctctc ctatgacacc ggcttcgtgc aggtatacgc ccacttgttc
     5581 cgaatatgcg gtgcaagcct tgaagaaata tggccctgtg aaaggattgt atcttgcggt
     5641 taaacgaata cttcgttgcc atccttgggg tgggagcggt tatgatccgg ttccgtaacg
     5701 ccatgggtta ttatgatata catacgcatc agatgccttt ccataaggag gatatcgcga
     5761 ttataaatag gatcgtgagt ccaatgggtg atatgcagcc gggttcactt cctgatacgg
     5821 ttattcgctc atatggtatt catccgtggt atatatataa tgtaaaggag cagatggatc
     5881 tacttagggt attggtgtct ggttcgggag tcgtggcgat cggagaggct ggacttgata
     5941 cactggccga atctccaatg gatttgcaaa aagaggtgtt tctggcacaa gccaatttag
     6001 cggaggaaac acataagcca ttaatcatcc attgcgtaaa agcgtgggcg gatctcattg
     6061 cctgtaaaaa ggccgtgaaa ccggagatgc cttggattat ccatggcttt cgaggtaatg
     6121 gtgaacttgc ctcccaattg gttcgcttgg ggttttatct ctcttttgga gatcgtttta
     6181 atccgtcggc tttgcgtgcc gcatggcctg atttcctttt cttggagacc gatgataaat
     6241 cgattgatat ccgcggggtc taccaaaatg tagcggaagc gttggatatt ccggaagaaa
     6301 agctgcggat tcaaatcgct aaaaacgttt ctatcttcca cctaaacgga taattatcaa
     6361 ttatcaattt tcgattctca attaaaaagt cgtacctttg cctcgtatga gataaagtga
     6421 caaatatatt aatgtaatac gatataaatt aatacgatga attttgtaga agaattaaga
     6481 tggaggggca tgatcgctga tatgatgccc gggacggaag agcaattgca gaaagagttg
     6541 acatcggcct atgtggggat tgacccaacg gcagactctt tgcatatcgg acacttagta
     6601 agtgtgatga tgctgaagca tttccaacgt gccggtcatc gtcctatcgc tttagtgggt
     6661 ggcgctaccg gtatgatcgg tgacccgtct atgaagtctg ccgagcgtaa tttgctggac
     6721 gaggctactc ttcgtcacaa tcaggattgc atcaagaaac aattggctaa gttccttgat
     6781 tttgactccg acgctcctaa tgccgctaag ttggtgaaca actatgactg gatgaagggt
     6841 tattctttct tgaattttat ccgtgatatc ggtaagcata ttaccgtgaa ctacatgatg
     6901 gctaaggatt cagtgaagaa acgtttgagc cgcgaatcta gtgtaggtat gtctttcacc
     6961 gagttttctt atcaattgct acaaggctac gattatttgt atttgtatga gcatgagggt
     7021 tgccgtctac agatgggtgg taccgatcaa tggggtaata tcacgactgg tacggaattg
     7081 atccgtcgta cgttgggagg ggaggcttat gccttgactt gcccgttgat cacgaaggcc
     7141 gacggtggta agttcggaaa gacggaatcc ggtaatatct ggttggatcg tcgctatact
     7201 tctccgtata aattctatca attctggttg aacgtaagcg acgctgacgc cgccaagtat
     7261 atcaagatct tcacggactt gagccaagaa gagatcgccg ctttggaggc ggagcaagag
     7321 gccgctcctc atttgcgtcc gttgcagaaa cgtttggcga aagaagtgac tgttatggtt
     7381 cactctttgg aagattatga ggccgctgtc gaggcttcca atatcttgtt tggtaactcc
     7441 actcacgagg ctttgttgaa attggatgag gacacattac tagccgtatt cgagggtgtt
     7501 cctcatttcg atatctcccg tgatgaattg gccgcaggaa tcaaggctgt tgatttatgt
     7561 actgaaaaag ccgctatctt cccttcaaaa ggtgagatgc gtaaattggt acaaagtggt
     7621 ggcgtaagtt ttaacaaaga gaaactagcg gaggttgaca ctgtaattga ttgttcttca
     7681 ctgcttgacg ataagtattt attggttcaa agaggtaaga aaaattatta tttgttgatc
     7741 gcaaagtaaa aaaataatca aaaaatttgc aaggtaagat tttattctta cctttgcatc
     7801 gctttagtaa agcaatcgga ttgtctcatg gtgtaatggt agcactacag tttttggttc
     7861 tgtctgtcga ggttcgaatc ctcgtgagac aactcaacaa tccagagaga g
//
LOCUS       DBMDTB010000141         7874 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_2489_length_7874_cov_11.617908, whole genome shotgun sequence.
ACCESSION   DBMDTB010000141 DBMDTB010000000
VERSION     DBMDTB010000141.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 7874)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 7874)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7874
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2489_length_7874_cov_11.617908"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..241
                     /locus_tag="ACZPB4_15575"
     CDS             <1..241
                     /locus_tag="ACZPB4_15575"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099674.1"
                     /translation="SSPILVLLVELCKSIKELLSLSFLDCGCKGKDFFLTSKFFDEKF
                     SSFFFSSRSPGGWKLSLGLANLIPYPRIPPRFHHF"
     gene            complement(416..832)
                     /locus_tag="ACZPB4_15580"
                     /pseudo
     CDS             complement(416..832)
                     /locus_tag="ACZPB4_15580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276832.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase family
                     metallohydrolase"
     gene            complement(854..1048)
                     /locus_tag="ACZPB4_15585"
     CDS             complement(854..1048)
                     /locus_tag="ACZPB4_15585"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099675.1"
                     /translation="MRFNVQLVMVVLLCVAGLTLVFCGFWVAPSGEIDNSVLVTFGEI
                     CTFAGALFGVDYSYKLKIKD"
     gene            complement(1038..1481)
                     /locus_tag="ACZPB4_15590"
     CDS             complement(1038..1481)
                     /locus_tag="ACZPB4_15590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HIR1099676.1"
                     /translation="MAQGFKLVLRPSKPGEKDSEKKFYAVSKTNGTSSMKTLCKLISA
                     RSTVSSADVKAVLDNLNFVLDMELQEGRIVRLGDFGSFRISVSSDGVTDKKDFNSSML
                     RPLRIIFTPGGELKDTKKTLEYSRISQDGTTAEAGGSDSDSLSEI"
     gene            complement(1682..2140)
                     /locus_tag="ACZPB4_15595"
     CDS             complement(1682..2140)
                     /locus_tag="ACZPB4_15595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010186000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099677.1"
                     /translation="MRERLGHKPTVKNFDAFLVTLGPDERESWKMDVCSLGYGDYYRK
                     MPGAYRKFIRKYMEHDRECERCYIRKYTVRGDLLYSPFRPELLLELVKLVEFTDRETP
                     PSSLEIASCLLMGFDYPGSVRGLASHLREAGHSAEAVLVLAGKREVTDEF"
     gene            complement(2558..3418)
                     /locus_tag="ACZPB4_15600"
                     /pseudo
     CDS             complement(2558..3418)
                     /locus_tag="ACZPB4_15600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018667.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
     gene            complement(4255..5499)
                     /locus_tag="ACZPB4_15605"
     CDS             complement(4255..5499)
                     /locus_tag="ACZPB4_15605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HIR1099678.1"
                     /translation="MMALQERLGRNKTILANFSYLSLLQVFAILFPLLTYPYLLRVIG
                     LELYGVIIFAQSIINYVSLVINFGFNMSGARNVAIYKQDRARLSRIVTSIYWCKFILW
                     LVCLVLYLSVISMVPFFEDHYWVYVLSFLLTFNELLLPIWFFQGIEKMKYITFVNLSA
                     RLLFVVAIFLFVHRQEDYLLVPLLNGIGAILAGCLSLYIVLGKERVRFSLMPVRELRS
                     AYKESLPLFVSILSTQIYVNVNKLVIGSFLGMLEVSIYDMADKVLLLMKLPASMIAQA
                     VFPKISREQNIRFINHVMFLSVGIALLFYISMFFGSDWLVYLLAGEHIEEASVIMRLL
                     GISAILTSINGFLGGNRLVPLGYSSVYMRVMVGNCLFFLTAMGLLWLTGSITMYTVTV
                     MAVGVEVFCFVSLVYRNWRLGL"
     gene            complement(5508..6827)
                     /locus_tag="ACZPB4_15610"
                     /pseudo
     CDS             complement(5508..6827)
                     /locus_tag="ACZPB4_15610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018652.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
     gene            complement(7232..7612)
                     /locus_tag="ACZPB4_15615"
     CDS             complement(7232..7612)
                     /locus_tag="ACZPB4_15615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099679.1"
                     /translation="MSSLPSGIRLMNLLRDHLTEIMDRERANLNSIHLYCTGSYWVSF
                     ERSAYQLRRVFPDSETTPLRLFAYPFPIVMVSVTDRSLRLYARKHILRRDETDYKLLT
                     VPGLPMADYHVWHAGEVEGLPQLT"
     gene            complement(7656..>7874)
                     /locus_tag="ACZPB4_15620"
     CDS             complement(7656..>7874)
                     /locus_tag="ACZPB4_15620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099680.1"
                     /translation="HATMRSMLPVIKAGQSRALLLVTLYGCTDSSLYQRMAHEGVDPW
                     LDEPSPKKSKSVLIRRLRDYDGWLKHNE"
BASE COUNT         2407 a         2078 c         1360 g         2029 t
ORIGIN      
        1 ctcttctcca atacttgtac tacttgttga attatgtaaa tctatcaaag aactcttgtc
       61 gctatcgttt ctcgattgcg gctgcaaagg taaggacttt ttcttaacct ccaaattttt
      121 cgatgaaaaa ttttcaagtt tttttttctc aagccgatct ccgggcggtt ggaaattatc
      181 gcttggccta gccaacctca tcccctaccc aaggatacct ccacgtttcc atcatttctg
      241 aagcgccgtt ctctctcgaa tgcgggtgca aaagtaatgc tataaaacat acggtccaaa
      301 tttatcgggt attatttttt agtttttttt tcaaggctta acaagttata taatgtacgt
      361 acgataaaac acaatatata gtatcctttt ttccaaaatc cactcatacc ccctcctatt
      421 taaataaaat ctgttttctg ttcacccctt gtttttttaa tgaaagatgt atgaatccct
      481 tcgtacgata aaggatcgcc tgatcaaaat tcaggcggct tgccaccaag tcctccaata
      541 gtcggttgcg gtccaccgtg taaatgtcta ccgcctcccc cttcatatgt tgcgagctag
      601 gggcacctcc caccaatcgg tttaactctt cgcttcgata gccactcatg atatacatag
      661 gctatcgatg atatatacgc aaaggttcca acaaccgcac cattagattc cgtatcgccg
      721 gtattacctc cgaaggcaac gcattattaa gtccaagttc caccgccatc gcactataaa
      781 caaactcgtc catacgaaaa tgctctgtca atctcttctc atccttttcc atcttaactc
      841 aaattttcaa ttttcaatcc ttaattttca atttataaga gtagtccacc ccaaacagcg
      901 cgccggcaaa cgtgcagatc tccccaaatg tgaccagtac gctgttatct atctcaccgg
      961 aaggagccac ccaaaaacca cagaacacta aggtaaggcc ggccacgcaa agtagcacga
     1021 ccattaccag ttgcacgtta aatctcactc aggctatcac tatcagagcc accagcctcc
     1081 gcggtggtac catcttggga gatccgtgag tactccagtg tcttcttcgt atccttcaac
     1141 tcacctcccg gagtgaaaat gatacgcagc gggcgcagca tactcgaatt gaaatccttt
     1201 ttatctgtta caccatcact gctcaccgag atccgaaaac tcccgaaatc gccgagcctt
     1261 acgatacgcc cctcctgaag ctccatatcc aacacgaaat taaggttatc caataccgcc
     1321 ttcacatctg ccgacgacac cgtactacgt gccgagatca acttacatag cgttttcata
     1381 ctagaggtac cattcgtttt cgacaccgca taaaactttt tctctgaatc cttctcgccc
     1441 ggcttcgacg gacgcaacac caacttaaaa ccttgtgcca tatcttttaa tttttatggt
     1501 tatatacccc ttatggagca cgacacaaag gtaagatggc ccagaagaga cgaacgttcg
     1561 tagttttatc catcaaacaa gtaatattca actaattaaa aataaaaaaa accaaaaata
     1621 cctcttttca aagacaataa aaacctgcta ttcttaacta acattcaaat ccatatctct
     1681 tttaaaactc atccgtcacc tccctctttc cagcgagcac caagactgct tccgcagaat
     1741 gccccgcctc tcgcaaatga gaagccaagc cacgcaccga gcccggataa tcaaacccca
     1801 tcaacaggca agaggctatt tccaaggagg aagggggagt ctcacgatcc gtaaactcca
     1861 caagcttcac tagctccaac aagagttccg gacgaaatgg ggaatacaac aaatcaccac
     1921 gcaccgtata cttacgtata taacaccgtt cgcactcccg gtcatgctcc atatacttcc
     1981 ggataaattt acggtacgcc ccgggcatct tcctataata atctccatat cccaaactac
     2041 acacatccat tttccaagac tcccgctcat ccggccccaa cgttaccaag aacgcgtcaa
     2101 aattcttcac cgtgggctta tgccccaatc tctctctcaa acgctcatag atctttttca
     2161 tcatgcgaac gcagggggaa tgtttatccc tgcgccgcat atggccggac accgtactta
     2221 catacggatt ttcaaataca tatataaaaa cagaaccagc cttctaaatc cctttacggg
     2281 aaaagaagac cggtacaaaa ccttgacctt atatcgattc tacaaaatct ctatcatcct
     2341 atcttttcat cacaaaaccc acatggttcc ttctcttttc ttgcaaatgc ctctggggag
     2401 gctcttcttt tttgacgcta tatttaaatc aacattaata gcataggccc tcacggataa
     2461 atccataaaa gcctcaaaga catcgaagac gattaaacaa ctgaatatca tttatataat
     2521 actattattt taagcgcaat ttacttttta tttcgctcta ttcatccaac acctcatatt
     2581 tagaatgctg gctcttgaac tcaggaacga tctccttcat ccgcttcacg atccgcatat
     2641 ccccctccac ggcacaagca tgtaccaagg catcaatccg cagattggcg tcagcatagt
     2701 catacgcacg gacttgggcg atcttgatct tcggatgaaa agtaggcttg gaggtctcct
     2761 cctcattgag tacctcctca tacaacttct ccccgtctcg caatcccgtg aaccggatct
     2821 cgattccctt caccccgctc agacgaatca tacgctcagc cagatccacg atccgtacag
     2881 gtttacccat atcgaacacg aagatctcgc ccccattacc catcgtaccg gcctctagga
     2941 ctagcttaca agcctccggt atcagcatga agaaacgaat gatatccttg tgcgtcaccg
     3001 taacaggacc gccccgcttg atctgctcct tgaataacgg gatcacggaa ccgttcgatc
     3061 ccagcacatt gccgaaacga gtcgtcacga attgcgtacg ccccctcacc ttcccatcct
     3121 tgatagcctg atccaagctc tgcacgtaga tctcgcaaat acgtttcgag cagcccatca
     3181 cgttcgtggg attcaccgcc ttgtcagtcg ataccatcac gaacttcctc gtgccgtatt
     3241 tcaccgacaa gtctgcgatc acccgggtac cgtccacgtt gttgcggaca ctctcctccg
     3301 gattatcctc catcataggc acatgcttgt aagccgcggc atgaaacacg taatccggac
     3361 gatgctcctc gaacagctcc tccatgcgtt cacgcacaca aatatcgctc acaaccgtct
     3421 ctaatagtat ccaatgaaaa ctcctgcatg tcaaacctaa aagcagaaaa ataactaatc
     3481 acaacatata taaacaaact aaacacacat aacgaaaata tatatttaaa tttaagttta
     3541 attccagtta tcataaaaac aaaaaacaca gcaaacaata gaactaaaaa gttcgttcta
     3601 cctccaccta taagagcata atcctatata tatatattat aatcatccga ttatacactc
     3661 gcttaaaaaa caaacaataa gctaatatag catttgagca ataaaacaat ggaggagcaa
     3721 agaatgtata aaaaacaaaa tctatgctat aaagatcatc atttagtatt tcaaaagcat
     3781 caactcctac aagattcata gataatacta cattccaata ttttacgagg agacttccta
     3841 ataaaatgat agacacaaaa agtattatta aatatttttt actataaata aaccgattca
     3901 aagaacgaga atataaatat acctttttgt ctaaacatat atttttatta acttttacag
     3961 aagaaaaacc taatataata gcagaaacat ttagtaacat gattacatat acttcatcag
     4021 ataccggata aagtccataa ggattgaaag tagatataac caaagatata aaccatatag
     4081 tccaaaaaga caatatgacc tttttcgaaa agctatccct tatcattctt tttatataca
     4141 cataaaaaaa gagaaaaaac gctataatga aaaacaacat attcttaata aatctctgtt
     4201 ataacacttt atttagatat atatcctaaa taagtattac tattttatta aaccctacaa
     4261 ccctaatcgc cagttcctat aaactaacga cacaaagcaa aacacttcca cccctacggc
     4321 cattaccgta accgtataca tagttatgct tcctgtcagc cacaacaagc ccatagccgt
     4381 cagaaaaaac agacaatttc caaccatcac tctcatatac acggacgaat agcctagcgg
     4441 gaccagacga tttcctccaa ggaaaccatt gatagatgtc aagatcgcag agattcccag
     4501 caatcgcata atgacagaag cctcttctat gtgttctccg gcgagaagat acaccaacca
     4561 gtcactaccg aagaacatac taatgtagaa aagtaaagcg atccctaccg acaagaacat
     4621 cacatgattg ataaaacgaa tattctgttc acgggaaatc ttcgggaaaa cggcttgcgc
     4681 tatcatggag gctgggagtt tcatcaaaag aagcacctta tccgccatat cataaatgga
     4741 aacctccaac atccccagaa aagaaccgat caccaattta ttaacgttca cataaatctg
     4801 tgtggacagg atcgaaacaa ataagggcaa gctctcctta taggccgatc gcaattccct
     4861 taccggcatc aaggaaaacc ttactctctc ttttcccaac acgatatata aagagagaca
     4921 acccgccagt atagccccga tcccgtttaa caaggggacc agcaaataat cctcttgccg
     4981 atggacaaac aagaatatag caaccacgaa caacaggcgg gcagataggt tcacgaatgt
     5041 gatatatttc attttctcaa tcccctgaaa gaaccagata ggtaacagaa gctcgttgaa
     5101 tgtcaaaagg aaagagagga catacaccca ataatgatcc tcaaagaacg gaaccatact
     5161 gatgaccgat aaatacagga ctaggcaaac aagccataaa atgaacttac accaataaat
     5221 ggatgtgacg atccgggata atcttgccct atcctgcttg taaatcgcca cgttcctcgc
     5281 tccggacata ttgaacccga agttgatcac cagcgataca tagtttatta tagattgagc
     5341 gaatatgatc acgccataca attccaagcc tataacccga agcaagtaag gataggtaag
     5401 caatggaaat agaatagcga atacctgcag caaactcaga taggaaaaat tagccagtat
     5461 ggtcttattc cttcccagcc tctcttgtaa agccatcatc taaagattca atccctaccg
     5521 aagatatccc tcgtatagac ctttcccaac acatcgtcca gacaatcatc ataacgattg
     5581 gctatgatgg cgtggctcat ctccttgaaa cgggcgagat cattcaccac ggcactgccg
     5641 aagaaagaac tcccgtcttc caatgcaggc tcatagacga tcaccttggc ccctttcgcc
     5701 ttgatacgtt tcatcacgcc ttgaatagag gactggcgaa aattgtcact gttcgatttc
     5761 atcgtcaaac ggtatacacc cacgacgcat tctcgctctt cggagcaccg gaaactgttc
     5821 ctctcgctat aatcgtagta gccggccttg cgcaacacct ggtccgcaat gaaatcctta
     5881 tgggtatgat tgctctccac gatcgcagtc atcatattct ggggaacatc ctgataattg
     5941 gcgagcaact gcttggtgtc cttcggcaga cagtagcccc cataaccaaa gctggggttg
     6001 ttataatgcg tgccaatacg aggatccagc cccacgccct tgatgatggc actcgaatcc
     6061 aaacctttca cttctgcata ggtgtccaac tcgttaaaat aacttacacg caaagccaga
     6121 taggtattag caaacaactt cacggcctcg gcctccttca ttcccatgaa tagcgccgga
     6181 atatcctgtt taatggcacc ttcttgaagc agggcggcga acgtgtgggc agccttctcc
     6241 aaacccggaa tatccgcaat cctctcgatc gcctcattct ccgcattgaa ttactcatcg
     6301 cttagcaatt tgggataacc aacgattata cggctgggat aaagattgtc ataaagcgcc
     6361 ttgctctcac gcaaaaactc cggagaaaac agcagattga gtcgctcaat acccttttgg
     6421 gcgtatctca gataaagact ccggcaatat ccgaccggaa tggtcgactt gatcaccatc
     6481 accgcccttg gattaacact caataccaga tcgatcacat cctcaatatg gtgcgtatca
     6541 aaatagttct tcaccggatc ataattggta ggagccgcaa taacgatgaa atcggcatca
     6601 cgataagcgg acgctccatc aagcgtagcc gtcaagttca actccttctc ctttaggtat
     6661 ttttcgatat actcatcctg aataggagat tgcttccggt ttagcgtctc caccttctcc
     6721 ggtataacgt caaccgcagt gaccggatga tgctgtgcca acagcgtagc aatactcaac
     6781 ccgacataac cggttccagc tacagcaatt ttgatttcct ctgacataat gattattgta
     6841 tataagtagt cacttcagat ccgtaacaga cccaaagcat ttgttttgac taaaaaaata
     6901 tcctaggttc atccaccatg tatcttaggt gcgttggtaa aatatcttag gttagtgacg
     6961 caagtcacct aagattgctc atgggtgtct atcgccccat tacccatctc atcggacggc
     7021 atttccttat gagtgccttt cagatggaaa tcaagatcac cttacgtaag gtctctttta
     7081 tcgaatttag cacgtccgct ttcattaatt tatgacaatt atttttcctc tagagtaaat
     7141 atacgaaatt tcatgctaat tgccaaccat caatcaaaat cattatacca taattgagtt
     7201 tattactttt ccagcgcttc atatttggag ttcatgtcag ctggggcaag ccttccacct
     7261 cgccagcgtg ccatacatgg taatccgcca tgggaagccc ggggacggtc aatagcttgt
     7321 aatccgtctc gtccctcctc aagatatgtt tacgggcgta caaacggagt gagcgatccg
     7381 taacggacac catcacgatc gggaacggat aagcgaacag gcgcagcggc gtagtctcgc
     7441 tatccggaaa cacacgacgc aactgatagg cagaacgctc gaacgacacc cagtaagatc
     7501 ccgtacaata caggtgtatt gagttcaggt tcgcacgctc acgatccatg atctctgtca
     7561 aatggtcacg caacaggttc atcaaacgga tgcccgaagg aagggaagac atgtcttgaa
     7621 ttatgatgta tgaattttga attattcatt attcattatt cattatgttt cagccaaccg
     7681 tcgtaatcac gtagacgacg tatcaacaca gacttacttt tcttgggaga aggctcgtcc
     7741 agccacgggt caaccccctc gtgcgccatg cgttggtaga ggctgctgtc cgtacagccg
     7801 tacagcgtga ccagcaacaa ggcacgggat tgccccgctt ttatcaccgg gagcatgctg
     7861 cgcatcgtgg cgtg
//
LOCUS       DBMDTB010000142         7734 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_2537_length_7734_cov_11.698415, whole genome shotgun sequence.
ACCESSION   DBMDTB010000142 DBMDTB010000000
VERSION     DBMDTB010000142.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 7734)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 7734)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7734
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2537_length_7734_cov_11.698415"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..212)
                     /locus_tag="ACZPB4_15625"
     CDS             complement(<1..212)
                     /locus_tag="ACZPB4_15625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HIR1099681.1"
                     /translation="MNYVFFGNNVPLAERLRKALGTGVIECITLLQMKNTLLPAEEMD
                     YCVFIEKTDPTLNIPAIMHLHKTFQN"
     gene            complement(212..577)
                     /locus_tag="ACZPB4_15630"
     CDS             complement(212..577)
                     /locus_tag="ACZPB4_15630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HIR1099682.1"
                     /translation="MEKSVLLVDDKQEIAKIIMLYLSSTYKVSYKENPLKAIAWLQEG
                     NLPDLIISDLNMPEMSGEEFLVYLKANDMFSHIPVLILSSVESSSNRIRLFEEGAEDF
                     ILKPFNPEELRVRVKRILR"
     gene            757..3246
                     /locus_tag="ACZPB4_15635"
     CDS             757..3246
                     /locus_tag="ACZPB4_15635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046556 - alpha-L-arabinofuranosidase
                     activity [Evidence IEA];
                     GO_process: GO:0046373 - L-arabinose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-arabinofuranosidase C-terminal
                     domain-containing protein"
                     /protein_id="HIR1099683.1"
                     /translation="MRWWKYIGFDVIYLLVGAIVGMGLSSCQPEMPVISTITVEADGL
                     TVPVNPDLYGLTIEEINHGIDGGLYAELIQNRSFEDGVPPLNCPYDAARNVLITPNGW
                     TIPFMRGDSVPGWRRIVPNTQIYPDMKELVNDKNRRSLLVAVSTSGESGRGGVIAEGY
                     RGIPIRKGERYDLSFFAKGANMVPRTIRVALEDSMANTVLSDVFQVAPPYEWRRYRHT
                     FTATEDAPNAVLTITADTSAVFWLDVVSLFPEDTWKGRKNGLRPDLAALVDSLAPRFI
                     RFPGGSFVEGYTAGTYPIWRETLGDISERKHFWNVWAYGTTNGMGYHEYLQMCEDMGA
                     EPIYVINSGITSQSRRPRYEDITAMDKLTGDALDAIAYANAPADSLPGALRARNGHPE
                     PFNLKYVEIGSENYGGEYFRRFELFRKAIKEAYPEITVISSSPLTKRGRSEWVDSHYY
                     AGEHFFLSNASRFNSDRYSRRSPAVFIGEFGTTERPLAGTLRAAVAEACFLVGAEENP
                     DMVRRLAYAPVLGNAGFENQRHPLISFNTHQAVVSPSYHLLKMFTRHRGDEVLKTIVD
                     TYEKPQVRTGRAGVEMFDNSYEFKDVRIDGVPVSDISVMSGGWKVPEAGTLVPEANRW
                     NHVLFGDSTSYAYEYTATVRRTKGSGQIQLRLRDNGRTGEQADYIALTIGAGTSELYH
                     QVGGVKDSLVSPVRFPFESNRWYTVRMTCEYERVRCYVDGVLLHEVDMRPIPSLVSVA
                     TLDKENRVIYLKVVNTTRHEEKTSLRIEGVNIRNEAELIQLRGEPEARNTFESPGAVT
                     PVTEPIVFPMSGPLIYNFPPNSVTILKLYME"
     gene            3327..4862
                     /locus_tag="ACZPB4_15640"
     CDS             3327..4862
                     /locus_tag="ACZPB4_15640"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIR1099684.1"
                     /translation="MEPMHKINKVELRSLQLEDYTQLSQSFKRVYADKDVFWTRKQIE
                     TLIRIFPEGQVVTLVDDRIVGCALSIIVDYDMVKGDHTYAKVTGNETFSTHNPNGNIL
                     YGIEVFIHPDYRGLRLARRMYEYRKELCEKLNLKAIMFGGRIPNYYKYADHMRPKEYI
                     EKVRSRQIYDPVLTFQLSNDFHVRKVMMNYLPNDEESKHCATLLQWDNIYYQPPTTDY
                     VDKKTTVRVGLVQWQMRPYKTLDDVFEQVEFFVDAVSDYKSDFVLFPEYFNAPLMAKF
                     NHLGEAQSIRGLAQYTEEIRERFVNLAISYNINIITGSMPLLKEDGALYNVGYLIRRD
                     GSYEMYEKVHVTPDEQKSWGLSGGKMVKTFDTDCARIGVLICYDVEFPELSRIMADQG
                     MQILFVPFLTDTQNGYSRVRVCAQARAIENECFVVIAGSVGNLPRVHNMDIQYAQSGV
                     FTPCDFAFPTDGKRAEATPNTEMILVSDVDLDLLNELHTYGSVRNLRDRRHDLYELRV
                     KKQ"
     gene            complement(5065..7416)
                     /locus_tag="ACZPB4_15645"
     CDS             complement(5065..7416)
                     /locus_tag="ACZPB4_15645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="family 20 glycosylhydrolase"
                     /protein_id="HIR1099685.1"
                     /translation="MKKLLATICAGAVLGLMASCDDAPGKAKAYNQGINIIPTPVSLT
                     QNEGNFKLNKNTKIYASTPEAKTVAEFFAAKMNTATGYQIATADKETSDGISLVIDGS
                     LDVNDEGYTLDVADSGVRIKAKTPQGLFYGMQSFLQLLPAEIESPSAVKGIAWTAPAV
                     SIKDEPRFGYRGIMLDPCRHFIPVENIKKQLDVLALFKINRMHWHLTDDQGWRIEIKK
                     YPKLTEIGSKRIDGEGTEYGGFYTQEEVKDIVKYAADRFITIVPEIELPGHEMAAIAA
                     YPELSCEGKQGTPRIIWGVEDIVLCAGKEEPFQFFEDVIAEVAPLFPGEYFHIGGDEC
                     PKTSWEKCPLCQARIRKEGLKGDKEHTAEEKLQSYFVQRMEKVVNKHGKKMIGWDEIL
                     EGGLAPSATVMSWRGEEGGIAAASMNHEVIMTPSSEGMYIDQFQGDYKINPVSIGGFT
                     TAERVYKYNPVPDTLAAAGKGHFIKGVQCNVWSEYLYNTDIMEYRIYPRILALSEIAW
                     SPLDRKDYKDFERRLDNAQVRLDGHGINYYIPQPEQPNGSCNFVAFTDKATMTFTTNR
                     PMKMVYTLDGTEPTPESTVYTAPFDITETTTVKIASVLPSGKMGKPRTILVEKQTLAP
                     AKEVAKTTPGLDMEVFDGMYLSVNNLEAAQKTGKKQVIKTTRELTNQVPAPESMRGVK
                     QYAAIATGYVNIPEDGVYYISSDLEEVWIDGKLMVNNGGEVKRFSRHDTSAALAKGLH
                     EIKLVFLGHIIGGWPSNWNDGSVQLRKSDAEKFTPITAEMLSH"
     gene            complement(7546..>7734)
                     /gene="glyA"
                     /locus_tag="ACZPB4_15650"
     CDS             complement(7546..>7734)
                     /gene="glyA"
                     /locus_tag="ACZPB4_15650"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008157671.1"
                     /note="catalyzes the reaction of glycine with
                     5,10-methylenetetrahydrofolate to form L-serine and
                     tetrahydrofolate; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HIR1099686.1"
                     /translation="FQTSGIRVGTPAITTRGAKEPLMGEIVELIDTVLAAPECDKTIG
                     AVREKVNGIMKEYPIFAW"
BASE COUNT         1700 a         1924 c         2205 g         1905 t
ORIGIN      
        1 atattttgaa acgtcttatg caaatgcatg atcgcaggaa tgtttaacgt aggatctgtt
       61 ttctcgatga atacacaata atccatttcc tcggcaggaa gaagcgtgtt tttcatctgc
      121 agaagcgtta tacattctat gaccccggtg cctaatgcct tacgtaaacg ttcggccaac
      181 ggcacgttat taccgaaaaa gacataattc attatcttaa tattcgtttt acccttaccc
      241 ttaattcctc tggattgaaa ggcttcaaga taaagtcttc cgccccttcc tcaaacaaac
      301 gtattctatt tgagctgctc tctacgctcg ataggatcaa gaccggtata tggctgaaca
      361 tatcgttcgc ttttaaataa accaagaatt cctctccgga catttctggc atattcaagt
      421 cagagatgat caaatccggt aaattgcctt cttgaagcca agcgatcgct ttcaaaggat
      481 tttctttata ggataccttg taagtacttg ataagtaaag catgattatc tttgcgattt
      541 cttgcttgtc atccactaaa agaacagatt tctccataga gccgtataat gttgtcgtct
      601 tttgttttat ttgtcatgca aatttagaac atttaattgg aaaaatctat gtttttcaat
      661 tgtttttttg aaaaaacagt tcggactttg aaaatagggg aaactgcgat tttttgatta
      721 agtttgtacg ctcataaatg agatgagtat tcgaagatgc gttggtggaa atatataggt
      781 tttgatgtta tttatttatt ggttggcgct attgtcggga tgggtttgtc ctcttgccag
      841 ccggagatgc cggtgatctc tacgataacc gtggaggcgg atggcctaac ggttcccgtg
      901 aacccggatc tgtatggttt gaccattgag gagatcaacc acgggatcga tggggggctg
      961 tatgccgagc tgatccagaa ccggagcttc gaggatggcg tgccaccctt gaactgccct
     1021 tacgacgccg cccggaacgt cttgattacc ccgaatggct ggacgatccc tttcatgcgg
     1081 ggagattccg taccgggatg gaggcggatc gtccctaata cacagatata cccggatatg
     1141 aaggagctgg tgaatgataa gaaccggcgg tcgttgctcg tggccgtatc gacttccggg
     1201 gagtcggggc gcggaggcgt gatagccgag ggataccggg ggataccgat ccggaaaggg
     1261 gaacgatacg atctctcgtt tttcgccaag ggggcgaata tggtgccccg taccatccgg
     1321 gtggccttgg aggactcgat ggctaatacg gtcttgagcg atgtgtttca ggtagcgccg
     1381 ccgtacgagt ggagacgata caggcatacg tttacggcta cagaggacgc gccgaacgct
     1441 gtcttgacga tcacggccga tacctccgcc gtgttttggc tggacgtggt atcgctcttc
     1501 ccggaggata cgtggaaggg acggaagaac gggctgagac cggacttggc ggcgctggtc
     1561 gattccttgg cccctcgttt tatccgtttc cccggaggca gtttcgtgga ggggtatacg
     1621 gcgggtacgt accctatctg gagggagacg ctgggcgata tctcggagcg taagcatttc
     1681 tggaacgtat gggcctatgg tacgacgaac ggcatgggct accacgagta cttgcaaatg
     1741 tgcgaggata tgggggcgga gcctatctac gttattaata gcgggatcac gagccaaagc
     1801 cgtcggcccc gctacgagga tatcacggcg atggataagc tcacgggaga tgccttggac
     1861 gctatcgcct acgcgaacgc cccggcggat tccctgccgg gcgccctgcg tgcgaggaac
     1921 gggcatccgg aacctttcaa cttgaagtat gtcgagatcg gcagcgagaa ctatggcggg
     1981 gagtatttca ggcgctttga gcttttccgc aaggcgatca aggaggccta tccggagatt
     2041 accgttatca gcagttcgcc cctcacgaag cgaggccgta gcgagtgggt ggattcccat
     2101 tattacgccg gggagcattt cttcctctcg aacgccagca ggtttaatag cgaccggtat
     2161 tcccggcgtt cgccggcggt gtttatcggg gagtttggga cgacggagcg gcccttggcc
     2221 ggtacgctcc gggcggcggt ggccgaggcc tgtttcttgg tcggcgcgga ggagaacccg
     2281 gatatggtac gccgcttggc gtatgccccg gtattgggca acgccgggtt cgagaaccag
     2341 cgccatccgt tgatctcttt caacacccat caggcggtgg tctctccttc ctaccattta
     2401 ttaaagatgt ttacccgcca tcggggggat gaggtgctga agacgatcgt ggatacctac
     2461 gagaagccac aggtacgtac gggccgggcg ggcgtagaga tgtttgataa tagctatgag
     2521 ttcaaggacg tgcggatcga cggcgtgccc gtatcggata tatccgtgat gagcggggga
     2581 tggaaggtcc cggaggctgg tacgttggtg ccggaggcca accggtggaa ccatgtattg
     2641 ttcggcgact ctacgagcta cgcctatgaa tatacggcta ccgtccggcg tacgaaaggt
     2701 agcgggcaga tacagcttcg cctccgcgac aacgggcgga cgggcgagca ggcggattat
     2761 atcgccctga cgatcggggc gggaacgagc gagctgtacc atcaggtagg tggcgtgaag
     2821 gatagcttgg tctctcccgt gcgcttccct tttgagagta accggtggta tacggttcgc
     2881 atgacgtgcg agtacgagcg cgtccgttgc tatgtggacg gcgtattgct gcatgaggtg
     2941 gatatgcgtc cgatcccgtc gttggtatcc gtcgctaccc tcgacaagga gaaccgggtg
     3001 atttacttga aggtcgtgaa tacgacccgc cacgaggaga agacctcttt gcgtatcgag
     3061 ggagtgaata tccgtaacga ggcggagctg atccaattga gaggggagcc ggaggctcgt
     3121 aatacgtttg agagcccggg ggccgtaacg cctgtcaccg agcctatcgt attcccgatg
     3181 agcggcccgc ttatctataa tttcccgcct aattcagtga cgatcttgaa attatacatg
     3241 gagtaggtca gatagggcag gagggccggt acactttatc tgtatttatc ctaacttcgc
     3301 ggcgacttta acaaaaaaaa tgtgttatgg aaccaatgca taagataaac aaggtagagc
     3361 tccggagctt gcagcttgag gactatacgc agttgtcgca atctttcaag agggtgtacg
     3421 ccgacaagga tgttttctgg acccgcaagc agatcgagac gttgatacgg atatttcccg
     3481 agggacaggt cgtgacgctg gtggatgacc ggatcgtagg atgcgccctc tccatcatcg
     3541 tggattatga catggtgaaa ggggatcata cctacgccaa ggtaacgggc aacgagacgt
     3601 tcagcacgca taacccgaac gggaatatat tatatggtat agaggtgttc atccatccgg
     3661 actaccgggg cctccggctg gcccgccgta tgtacgagta ccggaaggag ctgtgcgaga
     3721 agttgaactt gaaggcgatc atgttcggcg gacgtatccc gaactattat aaatacgccg
     3781 atcatatgcg tccgaaggaa tacatcgaga aggtgcgctc acgccagatc tacgacccgg
     3841 tgctcacctt ccagctctcc aacgatttcc acgtgcggaa agtgatgatg aactacttgc
     3901 cgaacgacga ggagtcgaag cattgcgcta ccctgctgca atgggataat atctattacc
     3961 agccgcctac gacggattac gtggataaga agacaaccgt gcgtgtcggt ctggtacaat
     4021 ggcagatgcg gccttataag acactggacg acgtgttcga gcaggtggag ttcttcgtcg
     4081 acgccgtatc cgattacaag agcgacttcg tccttttccc cgagtatttc aacgctccgc
     4141 tgatggccaa gttcaaccat ctgggcgagg cgcagagcat ccgtgggctg gcccagtaca
     4201 ccgaggagat ccgtgagcga ttcgtgaacc tcgccatcag ttacaatatc aatatcatca
     4261 ccggtagcat gcctttgctg aaggaggacg gggcgctata taacgtggga tacctgatcc
     4321 gtcgtgacgg ctcctacgag atgtacgaga aggtacatgt caccccggac gagcagaaga
     4381 gctggggact ctcgggcggg aagatggtga agacgtttga tacggattgc gcccggatcg
     4441 gcgtgctgat ctgctatgac gtggaattcc cggagctttc ccgtatcatg gccgaccaag
     4501 ggatgcagat cctcttcgtg cctttcctta cggatacgca gaacggttac tctcgggttc
     4561 gtgtatgtgc ccaagcccgg gcgatcgaga acgagtgctt cgtggtgata gcgggcagcg
     4621 tgggcaacct gcctcgtgtg cataatatgg atatacagta cgcccagtcg ggtgtgttca
     4681 cgccttgcga tttcgctttc ccgaccgatg gcaagcgtgc ggaggcaacc ccgaatacgg
     4741 agatgatcct tgtatcggac gtggaccttg atttgctcaa cgagttgcat acgtatggta
     4801 gcgtgcgtaa ccttcgggac cgtcgccacg acttgtatga gttgagggta aaaaaacagt
     4861 agtgtttgcg gttgaacaca atagtattca tggttgaacc cagtagtgtt cgctattaaa
     4921 cacaattata ttcgccggaa gaatgcagta ggggcgggat ctgtccgcct cccgtgccgt
     4981 gtatgcgtgg gagggcggac gaatcccgcc cctgcggttt atatcggggg gaggatcgct
     5041 cgcttccccc ctgcggaaat gatcttaatg acttagcatc tcagccgtga tcggcgtgaa
     5101 tttctcggca tccgatttac ggagttgtac gctgccgtcg ttccagttgg aaggccaacc
     5161 tccgatgatg tgtccaagga ataccagctt gatctcgtgc aagccctttg ccaaggccgc
     5221 ggaggtgtca tgacgggaga agcgttttac ctcgccaccg ttattgacca tcaacttgcc
     5281 gtcgatccat acctcctcta aatcggaaga gatgtaataa acgccatcct ccgggatgtt
     5341 cacgtagccg gtagcgatag cggcgtattg cttcacgcct cgcatggatt cgggggcggg
     5401 cacttggttg gtcagttcac gggtcgtctt gatgacctgt ttcttaccgg tcttctgagc
     5461 ggcctccaga ttatttacgc ttaggtacat gccatcgaat acctccatgt cgaggcccgg
     5521 ggtcgtcttg gctacctcct tggcgggagc cagcgtttgt ttctccacga ggatcgtgcg
     5581 aggcttaccc atcttgccgg aaggcaacac ggaagcgatc ttcacggtcg tagtctctgt
     5641 gatgtcgaaa ggagccgtat atacggtaga ttccggggta ggctcggtgc catccagcgt
     5701 gtagaccatc ttcatcggac ggttcgtggt gaatgtcatg gtagccttgt ccgtgaaagc
     5761 cacgaagttg caagaaccgt tcggttgctc gggctgcggg atgtagtagt tgataccgtg
     5821 tccgtctagg cgaacctgag cgttgtccag acggcgttcg aagtccttgt aatccttccg
     5881 gtccagcggg ctccaagcga tctcggagag ggctaggata cgaggataga tacggtactc
     5941 catgatgtcc gtgttataaa ggtactcact ccatacgttg cattgcacgc ccttgatgaa
     6001 atgcccttta ccggccgctg ccagcgtgtc ggggacgggg ttgtacttat agacccgctc
     6061 cgccgtggtg aatcctccga tagataccgg gttgatcttg tagtcgcctt ggaactggtc
     6121 gatatacatg ccctcgctgc tgggggtcat gattacctcg tggttcatgc tagcggcggc
     6181 gataccgcct tcctcacctc gccaagacat taccgtggcc gatggagcca gacctccctc
     6241 gaggatctcg tcccatccga tcatcttctt gccgtgcttg tttacgacct tctccatgcg
     6301 ttgtacgaaa tagctctgca atttctcctc ggccgtatgc tccttgtcgc ctttcaagcc
     6361 ttccttacgg atacgggcct gacaaagcgg gcatttctcc cagctcgtct tcgggcactc
     6421 atcgcctccg atatggaaat actcgcccgg gaatagggga gctacctcgg cgatcacgtc
     6481 ctcgaagaac tggaagggct cttccttgcc ggcgcataat acgatgtctt ccacgcccca
     6541 gatgatacgg ggagtaccct gcttaccctc gcaagacagc tccggatagg cggcgatagc
     6601 ggccatctcg tgtcccggaa gctctatctc gggaacgatc gtgatgaaac gatccgccgc
     6661 gtatttaacg atatccttca cctcctcttg ggtatagaag cctccgtact cggtaccctc
     6721 gccatcgatg cgcttagagc cgatctcggt cagtttcgga tacttcttga tctcgatacg
     6781 ccatccttgg tcgtcggtca ggtgccaatg catgcggttg atcttgaaca aggccaatac
     6841 atccagctgc ttcttgatat tctctaccgg gatgaaatgg cggcaggggt ctagcatgat
     6901 accacggtaa ccgaatcgag gctcgtcctt gatagatacg gccggagcgg tccatgcgat
     6961 acctttcacg gcggaaggac tctcgatctc ggcgggcagc aattgcaaga acgattgcat
     7021 accgtagaaa agaccttgag gggtcttggc cttgatacgg acgccgctgt cggctacgtc
     7081 gagcgtgtat ccctcgtcgt ttacgtccag agagccgtcg ataaccaacg agataccgtc
     7141 ggaggtctct ttgtcggcgg tagctatctg gtagcctgtc gccgtgttca ttttagccgc
     7201 gaagaactcg gctacggttt tcgcctccgg ggtggaagcg tagatcttcg tgtttttgtt
     7261 tagcttgaag tttccctcgt tctgcgtaag gctgaccggt gtcgggatga tgttgatacc
     7321 ttggttgtaa gctttcgctt taccgggagc atcatcacac gaggccatca ggcccaagac
     7381 agcgccggcg cagattgtag caaggagctt tttcatagaa ttaaaaattg aaagttgaaa
     7441 attgaatatt gtttagatgt ttttgagagt ttaaaaagag aattgagagt tgaagataag
     7501 atgccgtttg gcatcctttt caattctcaa ttctcaattt cctatttacc atgcgaagat
     7561 aggatattcc ttcatgatac cgttcacctt ctcacgaacg gcgccgatag tcttatcgca
     7621 ttcgggagcg gccaatacgg tgtcgatcag ttccacgatc tcgcccataa gcggctcttt
     7681 agcgccacgg gtcgtgatag cgggcgtacc cacacggata ccggaggtct ggaa
//
LOCUS       DBMDTB010000143         7647 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_2569_length_7647_cov_10.076862, whole genome shotgun sequence.
ACCESSION   DBMDTB010000143 DBMDTB010000000
VERSION     DBMDTB010000143.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 7647)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 7647)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7647
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2569_length_7647_cov_10.076862"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(210..1376)
                     /locus_tag="ACZPB4_15655"
     CDS             complement(210..1376)
                     /locus_tag="ACZPB4_15655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-bladed beta-propeller"
                     /protein_id="HIR1099687.1"
                     /translation="MKRFIFTGIIILFVMAGCGGDHSSTDGLITVDVNDSYSTKKELV
                     LQDFMDMEYIPLETNDEFINRACVQAVGEKYIIVTNFYDDGNIFVYGRNGKAIRKINR
                     KGQGGEEYVSMRSVSLDEENEEIFVNDFHAKKIRVYDLEGNFKRSLNQRSEKSSFYVE
                     MLDYDKDNLICYDKFNFEVPFLLVSKQDGSITKEITVPYKEKQLFHIVERLYDKGETR
                     AAGPGPYNSIIPFKGNWILFEASSDTVYTLMPDYSLRPLIARTPPIHTMDPGVFVVLR
                     LISDRYYFMESVTNIYDFNTGEGFPRKYFAYDTQEKKFFNYITYNDDYSYKKEIYMVT
                     FPPINSKGELCSTINASDLCQDYKRGKLKGKLKEVAATLEEDDNRVVVLVRPKK"
     gene            complement(1453..1929)
                     /locus_tag="ACZPB4_15660"
     CDS             complement(1453..1929)
                     /locus_tag="ACZPB4_15660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4252 domain-containing protein"
                     /protein_id="HIR1099688.1"
                     /translation="MINTMRLKQLYTILLLCCVNICFAQNKLFDKYADMDDVTSVYIS
                     KKMFQMMPVMETAGLNLANLKGKIESLQILTTQKADLRERMRGEFKALIGKDHEELMR
                     VKDGKTKANFYVKQQGELIQELIMIADMDDGSFSVMQLLGRFTLQDVQEITSEINK"
     gene            complement(1922..2314)
                     /locus_tag="ACZPB4_15665"
     CDS             complement(1922..2314)
                     /locus_tag="ACZPB4_15665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099689.1"
                     /translation="MDDKKIDELINKALQEDLALPEGLSERLERQIDFLAQEEVSPRV
                     SRRRSFYWISGIAAAILGALFLIFTETNRPAPVMADTFTDPEEAAVVAQNALAFMSRN
                     LNKGLGQVNEASQEITKINKIVNKHLND"
     gene            complement(2307..2819)
                     /locus_tag="ACZPB4_15670"
     CDS             complement(2307..2819)
                     /locus_tag="ACZPB4_15670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HIR1099690.1"
                     /translation="MDVDVFKQRFLPFHPKLYRIAYALLDNKADAEDILQDAYCKLWN
                     KRDELGDIQNPEAFSITLVKNLCLDFLRSPKASRRDNEEALETVLLTTDSSPEKELEE
                     KEDIRRIQELIEQLPENQRQVIRLRGIEDCSYEDIEQITGLSSSNIRTLLSRARKLIR
                     EKLEKASCHG"
     gene            complement(2831..3286)
                     /locus_tag="ACZPB4_15675"
     CDS             complement(2831..3286)
                     /locus_tag="ACZPB4_15675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4252 domain-containing protein"
                     /protein_id="HIR1099691.1"
                     /translation="MKRLLVLLAILLISQVGYGQQKMDQLFNAFRGESDVTSVNIGNI
                     TMKLASLFTETMGVNGIEIFEFDNCAQEVKDRLSTTIRNLRDPDYETMVTANERDSRT
                     KVLVKIKEDMIRELVIFTTGSDNALIRIKGKISPSDLDRVINEHKTGNH"
     gene            complement(3498..4445)
                     /locus_tag="ACZPB4_15680"
     CDS             complement(3498..4445)
                     /locus_tag="ACZPB4_15680"
                     /inference="COORDINATES: protein motif:HMM:NF024548.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrillin family protein"
                     /protein_id="HIR1099692.1"
                     /translation="MNKLLLITILLIIFTGCHENQQWMSKEKSTARKSVLEMTTRSYT
                     AGSSVFTEILPEGSEIGLFITYGNQDSLYKGASLYKNVKSKAVGSSKGSLKWKQTPQV
                     FLRSNRPVMIYAYSPYKVQIPLDPTSIPIKISPIAAEPPSYEYGRLSQGQKEVNRKSP
                     LAKLSMNYALSLLSFEIYQDSDINGLFKLTSIQIGNRAGGNTLQYTGTMDIVTGNIKG
                     TPGAYKATLLTIDPSVTLRHAKAEEQNIRIVPTYSPIREKEVEAIFTINGRTYKYIIP
                     EGTCWNKGYKYSYKLYFDGKDIRLHDSVAYIWTPKLKKK"
     gene            complement(4948..5916)
                     /locus_tag="ACZPB4_15685"
     CDS             complement(4948..5916)
                     /locus_tag="ACZPB4_15685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrillin family protein"
                     /protein_id="HIR1099693.1"
                     /translation="MRNLVLFTSMILSFWGCSNDKDFGGLENIGWNEKPLQITTRILT
                     TKSTNFIQEFKEGSMLGLQITSGTVDDLYNGISTYKNVSVKAYRVNGKIRWQQSPEVI
                     LDSNEATIYAYYPYQEDINFNARQIPVKLAPNALETDDYMYGTHAIGQKAVNSTSPLV
                     LLSMNHALSLISFQLNLSKGKTGAFIISSVQVGNKPGGTTLVSEGTLDITTGDIIGST
                     ARSTSASTVLSLTNPVTLINEKYCDPMRLMVIPPSGTIGTGDVETLFTINGETYKFDI
                     PANTQWEKGKKYLYKLSFNGRSLQLRDVSITDWLPGNDEGLIGNIM"
     gene            6121..7266
                     /locus_tag="ACZPB4_15690"
     CDS             6121..7266
                     /locus_tag="ACZPB4_15690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIR1099694.1"
                     /translation="MLDKIQFLLSLQILGFCVFGGITLLLRARENRAKQILGWSMLLW
                     AFLAAVRVSVNLYLEDSKEIFHPDVLIMGCIVVATLACYVIEVLRPCYMTVRRFFIFT
                     SPIWVLGISFLIYRLSGGNIHRYNSFGEVFDTLNLDVVIRLLILFFTLLYMIVPIYLI
                     LRYSEGFKVYLRENVSDPEDYDLDWLKKTMLILSSMYIFYLVLLFTDRVSLYVIDKTF
                     LLVLWYYFFYKALFLKVIHLDHTFESGWGLPDLEEDTDDDQGSEEQKGIIRQRYVEEV
                     QAWFEREKPYLREDLRLTDLQRIFPMSRSYLSQLFNKELGCSFSDYVNHFRVEESKRL
                     LEAEPLASIQEIAERSGFHSISTFRRAFIKQTGVIPSEYRRDGNESI"
     gene            complement(7258..>7647)
                     /locus_tag="ACZPB4_15695"
     CDS             complement(7258..>7647)
                     /locus_tag="ACZPB4_15695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolB family protein"
                     /protein_id="HIR1099695.1"
                     /translation="TAEGLDDGPEYSPCGQYIWFNSVRTGLMQVWRMKADGSEQTQMT
                     FDETRNSWFPHISPDGKQIVFITYTKGDLEPGQHLANKNVELRLMPAEGGEPKTLVKL
                     FGGQGTINVNSWAPDSKRFAFVSYRLN"
BASE COUNT         1956 a         1506 c         1665 g         2520 t
ORIGIN      
        1 gtaaaagcga tcgcctctgc cgccgagggg tatcagctga gtttcttcca gttggatgat
       61 ccggtgttga gccaagtacg ggatgagatc aagaacttgg aggtgaataa tcttaccccc
      121 ttggaagcct tgaacaaact gagtgagatt aagcggatta ttacagggaa ataatccgct
      181 tgatcgtatt acagatgatt ggtaatcgtt tactttttag gtctcaccaa cactaccacc
      241 cggttgtcat cctcttccaa tgtcgcggcc acctctttta gtttgccttt cagctttccc
      301 cttttatagt cctggcaaag atcggaagca ttgatggtag aacacaattc gccttttgaa
      361 ttgatgggag gaaatgtcac catatagatt tctttcttat aagaataatc atcgttgtat
      421 gtgatatagt tgaaaaattt cttttcttgc gtatcgtatg cgaagtactt tctcgggaaa
      481 ccttctcctg tgttaaaatc atatatattc gttacgcttt ccatgaaata ataacgatcg
      541 gaaatcaatc ttaagacgac gaaaacgccc ggatccatgg tgtggatagg gggtgttcgt
      601 gcgataagcg ggcgcaaact gtaatcaggc attaaggtgt ataccgtatc tgaagaggcc
      661 tcaaatagaa tccaattacc cttaaaagga attatactgt tatacggacc tggtccagct
      721 gctcttgttt ctcctttatc ataaagtctt tcaacgatat ggaataattg cttctcttta
      781 tatggaaccg tgatttcttt cgttatactt ccatcttgct tcgacacaag caagaacggt
      841 acctcaaaat taaacttatc atagcaaatc aagttgtcct tgtcataatc aagcatttcc
      901 acgtaaaacg aacttttctc gcttctttga ttcagacttc gtttgaaatt tccttccaaa
      961 tcatagaccc ttatcttttt cgcatgaaaa tcatttacga aaatctcttc gttttcttca
     1021 tctaacgaaa ccgatctcat agacacgtat tcttctccac cttgtccctt gcgatttatt
     1081 ttgcgaatag cttttccgtt ccggccatat acgaaaatat tgccatcatc gtaaaagttt
     1141 gtcacgatta tgtatttctc gccaaccgcc tgcacgcatg cccgattgat aaactcatcg
     1201 tttgtttcca gcggaatata ctccatatcc atgaagtctt gaaggaccaa ctcttttttg
     1261 gttgaataac tatcgtttac atccacggtt ataagaccat cggtcgatga atggtcgcct
     1321 ccacatccag ccattacaaa caggatgatt atccctgtaa aaatgaatct tttcatatgc
     1381 gtatgatttt tgtttaactt atggtggtga agatactata aaaagccgat ggttttcacg
     1441 aaattatcct aattatttgt tgatctcact ggtaatttcc tgcacatctt ggagcgtaaa
     1501 acgccctaac aattgcatga cgctgaagct cccgtcgtcc atgtcggcta tcatgatcaa
     1561 ctcctgtatc agttctcctt gttgcttgac gtagaaattg gctttggtct ttccatcttt
     1621 tactcgcatg agttcttcat gatcctttcc gatcaaggct ttgaactcac ctcgcattcg
     1681 ttcccttaaa tccgcttttt gggtggtgag tatttgcagg gattctattt tccctttcag
     1741 gttggcaagg ttgagtccgg cggtttccat gaccggcatc atctgaaaca tcttcttgga
     1801 gatatatacg gaagtaacat cgtccatatc cgcatatttg tcgaaaagct tgttctgggc
     1861 aaaacagata ttcacgcagc agagaagcag tattgtatat agttgtttga gtctcattgt
     1921 attaatcatt taaatgttta tttacgatct tgtttatttt tgtgatctct tgactggctt
     1981 cattgacctg cccgagacct ttgtttaaat tcctagacat gaacgccaag gcattttggg
     2041 ctacgacagc tgcctcttca ggatcggtaa aggtatcggc cataacggga gccggacgat
     2101 ttgtctccgt gaagatgagg aatagggcgc caagaatagc ggcggcgatt ccgcttatcc
     2161 aatagaagga acgtcttcgt gagactcggg gagatacctc ttcttgggct aggaagtcga
     2221 tttgtcgttc cagcctttcg gaaagtccct ccggtaaggc taaatcctct tggagtgcct
     2281 tgtttattag ttcatctatc tttttatcat ccatgacaac ttgctttttc tagtttctcc
     2341 cggatcaatt tgcgtgcccg ggaaagtaat gttcttatat tagaggagct aagccctgta
     2401 atctgttcaa tgtcctcata ggaacaatcc tcaataccac gcaggcggat tacctgcctc
     2461 tggttctcgg ggagctgttc tatcagttct tgtatacgcc ggatatcctc tttttcttcc
     2521 aattcctttt ccggcgagga gtcggtcgtt aatagaacgg tctccaatgc ctcttcgttg
     2581 tctcttcggc ttgctttggg cgagcgcagg aaatccagac aaagattttt gaccaatgtt
     2641 atggaaaatg cttccggatt ctggatatct cccagctcat cccttttatt ccataatttg
     2701 caataggcat cttgaagtat gtcttccgca tccgctttat tgtctaataa ggcataagcg
     2761 attcgataga gtttaggatg aaagggtagg aaccgttgtt taaaaacatc aacgtccatc
     2821 ggtatcgccc ttaatgattt ccagttttgt gctcattgat tacccggtct agatcggacg
     2881 ggctgatctt tcctttgata cggattaacg cattgtcgct tcctgtcgtg aatatgacca
     2941 gttcacggat catatcctct tttattttga caagaacttt cgtgcgactg tccctttcat
     3001 ttgccgtgac catcgtctcg taatcaggat ctctcaggtt ccgtatggtg gtagacagtc
     3061 ggtctttcac ctcttgggca caattatcaa attcaaagat ctctataccg tttactccca
     3121 ttgtctcggt gaacaggctg gctagcttca tcgttatgtt tccgatattt acggaagtaa
     3181 catcgctttc accccggaaa gcattgaata attgatccat cttctgctgc ccgtatccta
     3241 cttggctgat aaggaggatg gccagtaaca ctagtaatct tttcattgta attgactttt
     3301 tcgttaatac tatgtttttg gatcgccctt cgtccgtgcg ccttagagtg ggggctttca
     3361 caaagaagac gggataaggg atttgtttgt tacaaaaata ggcaaaaaag attagagtcc
     3421 gggcgtattt attctcgata ggctttacgg taagaatgaa aagttccata gattagtact
     3481 cttattttat atactgatta ttttttcttc agtttaggtg tccatatata ggcgacggaa
     3541 tcgtgtaacc tgatatcttt accatcgaaa tataacttat aggaatattt atatccttta
     3601 ttccagcagg tgccttccgg aatgatgtat ttgtaagttc ttccattgat agtaaagatc
     3661 gcctcaactt ctttttcccg gataggagag taggtaggga ctatacggat attttgctcc
     3721 tccgctttcg cgtgtcgtaa agttacggat ggatctattg taagtaaagt ggctttatat
     3781 gccccgggag ttcctttgat atttccggtt acgatatcca ttgtcccggt atattgcaag
     3841 gtattacctc ccgcacggtt accgatctgt atggaggtta gcttgaatag cccgttgatg
     3901 tccgaatctt gatatatttc gaatgagaga agtgataatg cataattcat ggagagtttc
     3961 gcgagcggag atttacggtt gacctctttt tggccttgcg agagcctccc atattcataa
     4021 gaggggggtt ccgccgcgat tggggatatt ttgatcggta tggaggtagg atctaacggt
     4081 atttgtactt tataaggtga gtaagcgtag atcatgactg gtcgattaga tctaaggaat
     4141 acctgcggtg tttgtttcca ttttaaagaa ccttttgatg agcctacagc ctttgatttt
     4201 acgtttttat aaagagatgc gcctttatat aaactgtctt gattaccata ggttataaat
     4261 aatcctattt cggacccttc gggcagaatt tcggtgaata ctgaagaacc tgccgtatag
     4321 gaccgggtgg tcatttcaag aactgacttt cgtgcggttg atttctcttt ggacatccac
     4381 tgctgatttt catgacatcc ggtaaagatg attaacaaga tcgtaattaa taataatttg
     4441 ttcattttgt ctaatgtttt aatggaacct ttcaaacaat aaacatttga gccaatatag
     4501 tttattattc tattactatt aattattatt cctgttataa aatgatattt ttatatatta
     4561 tatagtaacg attgttttat cctcttaata cgcaaagtaa tctgctttat tgtatactat
     4621 aataatcaat atatccaaga gatataaagt tattattaaa cgggtctcgt ccttgtaata
     4681 gtcaaataga agagtgtttt tggcgataag ttgagaggga atgataaccc ttgaatgtaa
     4741 aagggtattt ggacgagacc cgttgtttct cttattgaga gaatatatag agtcggctga
     4801 atgaaaaaca catcgtacgg gtagtgaccc cgatggtcta attcgccgga atgatagagc
     4861 caattgttat tttcagtgta gttgccggtg gcaaacggat caaagcttgc cacggcatta
     4921 caccttaata accacaacat aaaaaactta catgatattg ccaatcaatc cttcgtcgtt
     4981 acccggtaac cagtctgtga tagagacgtc tcgcaattgt aacgaccttc cgttaaagct
     5041 tagcttatat aaatattttt tccctttttc ccattgggtg ttagcgggta tgtcaaattt
     5101 gtaggtttct ccgttgatcg tgaataaggt ctccacgtct ccggttccga tcgtgccgga
     5161 aggtggaatt accatgagcc gcataggatc acaatatttc tcgttgatga gggtaaccgg
     5221 attcgtcaag gataataccg tggatgcgga cgtgctacgg gcggtagaac cgatgatatc
     5281 gcccgtcgtg atatcgaggg ttccttcgct gactaaagtt gttccaccgg gcttatttcc
     5341 tacttgaacg gaacttataa taaaggcacc tgtcttgcct ttgcttaggt tcaactggaa
     5401 agatataagc gatagggcat gattcatgct gagtaataca agtggcgagg tactgttgac
     5461 cgctttttgt ccgatcgcat gggttccata catataatca tcggtctcca atgcgttcgg
     5521 ggccagttta acaggtatct gccgggcgtt aaaatttata tcttcttgat atggataata
     5581 tgcgtatatc gtagcttcat tagagtcaag gatcacttcc ggactctgtt gccaccggat
     5641 ttttccattc actctataag cttttacgct tacgttttta taagtggata tgccattgta
     5701 taaatcgtcg actgtaccgg acgtgatttg tagtccgagc atagagcctt ctttaaattc
     5761 ttgtataaaa ttggtggatt ttgtagttag gatacgagtc gttatttgga gtggtttttc
     5821 attccagccg atattctcaa gacctccgaa gtctttgtcg ttggagcaac cccaaaagct
     5881 taaaatcata ctggtaaaga gtactaaatt tctcattatt ttacttattt ttgtgtgaaa
     5941 cttctggatg caaatatcgg gtggtcaagg ggaaagggag gtgcatacgg tctaaaacgt
     6001 cggtgaaatc gtataaaatt agatcgttca aattgtctaa ggtgttcata ttgttaactg
     6061 aggggtcaaa aagaacattc gggggggcgt attgtttaat agataggagg tagtgttatt
     6121 atgttggata aaattcagtt tctactaagc ttacagatat taggcttttg tgtttttggt
     6181 ggtattaccc tgctactacg ggcccgtgag aatagggcaa aacagatttt ggggtggagt
     6241 atgttattat gggcgttttt agcggcggta cgagtatcgg ttaacctgta tttagaggat
     6301 tcaaaagaga tatttcatcc ggatgtgctg attatgggat gtattgtggt agctacatta
     6361 gcttgttacg tgatagaagt gttacgacct tgctatatga ccgttcgccg tttctttatt
     6421 tttaccagtc cgatatgggt attgggtatt tcttttttga tttaccggct atccggtgga
     6481 aatattcatc gttataactc ttttggcgag gtattcgata ccttgaatct ggatgtggtt
     6541 ataaggcttt tgattttatt tttcacgctt ctgtatatga tcgttcctat ttatctgatc
     6601 ttgcgctata gtgagggatt taaggtgtat ttaagggaaa atgtatcgga cccggaagat
     6661 tatgatctgg actggttgaa aaagaccatg ctgatccttt cttctatgta tattttttat
     6721 ttggtattgt tgtttacgga tcgggttagc ctatatgtaa tcgacaaaac gtttttattg
     6781 gttttatggt actatttctt ttataaggcc ttgttcctaa aggttatcca tttggatcac
     6841 acattcgaga gcggatgggg attacccgat ttggaggagg atacggatga tgatcaaggt
     6901 agtgaggaac agaaaggcat catacgccaa aggtatgttg aggaagtaca ggcgtggttt
     6961 gaacgtgaaa agccctatct acgggaagat ttacgcttaa cggatttaca gcggatcttc
     7021 ccgatgagcc gctcttatct atcccaattg tttaataaag aattaggttg ttccttctcg
     7081 gattacgtaa accatttcag ggtagaggaa agcaaacgtt tattggaagc cgaacctctg
     7141 gccagtatac aagagatagc cgaacgttcg ggcttccatt ctatcagtac gttccgtcgt
     7201 gcgtttatta agcagacagg ggttattcct tccgaataca ggagagacgg gaacgagtca
     7261 atttaaccgg taactgacga aagcgaatcg cttgctatcg ggtgcccaag agtttacgtt
     7321 tatcgtacct tgcccgccga atagtttgac taaagtctta ggttctccgc cctcggctgg
     7381 cataaggcgt aactctacgt ttttattggc gaggtgttgt ccgggttcca gatcaccttt
     7441 tgtataggtg atgaaaacga tttgttttcc atccggagag atgtggggaa accaagaatt
     7501 tcgggtctca tcgaatgtca tctgggtttg ttcggaacca tccgccttca tgcgccagac
     7561 ttgcataagc ccggtacgta cggagttgaa ccagatatat tgtccgcaag gtgagtattc
     7621 ggggccatcg tccaaacctt cggctgt
//
LOCUS       DBMDTB010000144         7576 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_2598_length_7576_cov_12.300201, whole genome shotgun sequence.
ACCESSION   DBMDTB010000144 DBMDTB010000000
VERSION     DBMDTB010000144.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 7576)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 7576)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7576
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2598_length_7576_cov_12.300201"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            84..638
                     /locus_tag="ACZPB4_15700"
     CDS             84..638
                     /locus_tag="ACZPB4_15700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5025 domain-containing protein"
                     /protein_id="HIR1099696.1"
                     /translation="MKQVIYFLFSMLLFLSISCNKGEDISFEETPYYLGYFEGKVNSQ
                     DISIANQSNSHSFIDHGNFWQEVNTDLSGFYWEIPLGVHISDYPYPMLRISLIPLREG
                     EYLIDKGKLLNEEIESTVRITKDDAKIVYHPLKSSFRIQVDSIRFHEGSGTPYIEGKM
                     EGILYNIENSEDSIVIKDAIFGIH"
     gene            751..1206
                     /locus_tag="ACZPB4_15705"
     CDS             751..1206
                     /locus_tag="ACZPB4_15705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099697.1"
                     /translation="MKKLFVLLILLLSFGRSQAADIEARTGILGGDGWGLQTGAYINF
                     PQSRLFSIQTGLLLHTAGNSFSYGDDWNIDFFVPVYASFHIPLSDKVNLRLNAGAYTG
                     SGEYWNLGATAVAGIEVKRFYVGVNYFQNCVNDRDLKLGLSVGYKFTLF"
     gene            1538..2983
                     /locus_tag="ACZPB4_15710"
     CDS             1538..2983
                     /locus_tag="ACZPB4_15710"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PA14 domain-containing metallophosphoesterase"
                     /protein_id="HIR1099698.1"
                     /translation="MKKTFLLAIALLCFCVPMSLFAQKQLAFKDGKFKIVQFTDIHWD
                     QKSSKCAKTVATIQSVLKAENPDVAMLTGDVVTASPGLEGWKSVIGIFEEAKIPFTVM
                     MGNHDAEIVPKDEIYAMLSKSPYFMGEKGPGDIHGAGNYVVPVYSSDGKKPAALLYCI
                     DSNDYPTLKDYGTYDWIHFDQIHWYREQSMRYTKENGGKPLPALAFFHIPLLEYNEIV
                     GAETTLGQKEEGIASPKINTGFFASLVEMKDVMATFAGHDHDNDYIGMLYNVGLAFGR
                     VSGWDAYGDFERGGRIIELREGKFEFDSWIRTPSGKEYTYYYPSGLTSKDEETMEFLP
                     AKTVKPKKHGVVYTYYEGKFKHTDQIASGTKVKEGTMKNISIQEAPAKDHFAYEFRTL
                     INIPEKGVYRFYTYSDDGSKLFIDGKAIVDNDGSHNARIAKGKVALDAGFHELRVLYF
                     EDYMGEALEVGVSCRKIKEAVLPEDWYYLPE"
     gene            complement(3037..4716)
                     /locus_tag="ACZPB4_15715"
     CDS             complement(3037..4716)
                     /locus_tag="ACZPB4_15715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HIR1099699.1"
                     /translation="MKNKFDFQPKLFTALRNYSKERFMTDLMAGIIVGIVALPLAIAF
                     GIASGVSPEKGLITAIIGGFIVSLLGGCNVQIGGPTGAFIVIVYGIIQNFGIEGLAIA
                     TVIAGIILVLMGVLKLGTVIKFIPYPIVVGFTSGIAITIFTTQMKDLFGLTMDKVPAD
                     FISKWIAYFGAFDTVNPWAFVIGIISILIITLSPRLTKKIPGSLIAIVIMTIVVYIMR
                     NHLGITGIETIGDRFTINASLPAPAPITFNMETINLLLPSAFTIAILGAIESLLSATV
                     ADGVTGDKHNSNTELIAQGAANIIVPIFGGIPVTGAIARTMTNINNGGRTPVAGIIHA
                     IVLLLILLFLGPLTKHIPMACLAGVLIIVSYNMSEWRTFRSLMKNPKSDVSVLLVTFF
                     LTVIFDLTIAIEIGLLIAMLFFMRRVAETTHVSVTTDEIDLSDEGEIHHDEEVLSLPK
                     GVEVYEIDGPFFFGVANKFDGIMKSMGDKPKVRIIRMRKVSFIDSTGLHNLESLFRLS
                     EAEHIHMILSGVNEHVHRVLTKSGFDKKIGAENICSNINEAVEKAKAAVQD"
     gene            5006..5584
                     /gene="rbr"
                     /locus_tag="ACZPB4_15720"
     CDS             5006..5584
                     /gene="rbr"
                     /locus_tag="ACZPB4_15720"
                     /EC_number="1.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008146779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0016692 - NADH peroxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin"
                     /protein_id="HIR1099700.1"
                     /translation="MEKSIKGTRTEQNLLKSFAGESQARSRYTFFASVAKKEGYEQIA
                     GVFMETAEQEKEHAKRFFKFLEGGMVEITASYPAGVIGTTAENLAAAAAGENEEWAEL
                     YPEFAKIAEEEGFPAIAVAFKMIAKVEAEHENRYRKLLNNVETGTVFEKAEAILWQCR
                     NCGFVFEGKKAPVNCPACAHPQAYFEPMKQNY"
     gene            complement(5660..7231)
                     /gene="nadB"
                     /locus_tag="ACZPB4_15725"
     CDS             complement(5660..7231)
                     /gene="nadB"
                     /locus_tag="ACZPB4_15725"
                     /EC_number="1.4.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008734 - L-aspartate oxidase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD+ biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-aspartate oxidase"
                     /protein_id="HIR1099701.1"
                     /translation="MVQRFDYLVIGSGIAGMSFALKVANEGKSVALICKAGQEEANTY
                     FAQGGIASVTNLKVDNFEKHIEDTMIAGDWISDRAAVEKVVREAPAQIEALIRWGVNF
                     DKKESGEFDLHKEGGHSEFRILHHADNTGAEIQTSLIETVNNHPNITVFTNHYAVEII
                     TQHHMGIIVTRHTPGIKCFGAYVLNEDTGEVHTFLSKITVMATGGCEAVYRNTTNPLV
                     ATGDGIAMVYRAKGSVKDMEFIQFHPTALYHPGDRPSFLITEAMRGYGAVLRNLGGEE
                     FMHKYDPRLSLAPRDIVARAIDSEMKQRGEDHVYLDVTHKDPEETKKHFPNIYKKCLS
                     LGIDITKDYIPVAPAAHYLCGGIKVDLNGQSSIRRLYAIGECSCTGLHGGNRLASNSL
                     IEAVVYADAAAKHSLSVMDRYEFNQDVPEWNDEGTITNEERVLITQSMKEVNQIMEAY
                     VGIVRSNTRLIRAWNRLDILYEETESLFKRCKASRELCELRNMINVGYLITRQAMERK
                     ESRGLHYTIDYPPIK"
     gene            complement(7385..>7576)
                     /locus_tag="ACZPB4_15730"
     CDS             complement(7385..>7576)
                     /locus_tag="ACZPB4_15730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099702.1"
                     /translation="PLPDNKWIQSLRCYFSVNNVFTLTGYTGGDPANINVNGVEPGIE
                     TTSIYPVARTFTLGLSVQF"
BASE COUNT         2119 a         1514 c         1784 g         2159 t
ORIGIN      
        1 atttaagata gaatgtacga actgattctg ttaaagtagg taattgataa ataagaatta
       61 tatttatata aaattattgt aatatgaaac aggtaatcta ttttttattt agtatgttat
      121 tatttttgtc tatatcttgt aataaaggtg aagatatttc ttttgaagaa actccttact
      181 atttggggta ctttgaagga aaggtgaata gtcaagatat ttctatagct aatcagtcga
      241 actctcattc ttttattgat catggaaatt tttggcagga ggtaaatacc gatttaagcg
      301 gtttctattg ggagatacca ttaggagtgc atatctctga ctatccttat cctatgctga
      361 ggatctcatt gattccattg agagaaggag aatatctgat cgataagggt aaattattga
      421 atgaagagat agaatctact gttaggatca cgaaagatga cgctaaaata gtgtatcatc
      481 cactgaaatc ttcatttcgg atacaagtgg atagtattcg ttttcatgag ggaagtggta
      541 ccccttatat tgaagggaag atggaaggca tcctatataa tatagagaat tcggaagatt
      601 cgatcgtcat aaaagatgct atattcggaa tacactaact tggagccgaa taatgatata
      661 gaagcaatat ttagattgaa tgggagttct atatcatgat atgtcgaact tttattcaat
      721 ctaaatatta attttaatac cttgtaagta atgaagaagt tgtttgttct gttaatattg
      781 cttttatctt ttggtcgatc gcaggccgct gatatagaag ctcgtaccgg aatactagga
      841 ggagatggat gggggcttca gacgggggcg tatataaact ttccacaatc acggttgttt
      901 tctatacaaa cgggattgtt gttgcatacc gcggggaatt cgttttcgta tggggatgat
      961 tggaatattg atttttttgt acccgtttat gcttcttttc atattccgtt gagcgataaa
     1021 gtgaatctcc gattaaatgc gggtgcttac accggtagtg gtgaatattg gaatctggga
     1081 gctacggcgg tggccggtat agaggtaaaa agattttatg tgggagtgaa ctatttccag
     1141 aattgcgtca atgaccggga tttgaaattg ggtttgtcgg ttggatataa attcacatta
     1201 ttttaatctt ttatatattt tgaggatagg ggtatttgag cgtttcctgt cttacgataa
     1261 aaacaacgag aattatggag tcaacaagta aaaaacagaa tacccctaaa ctttggtact
     1321 ggggggagcc taagggagga atgagccttg aggattgtga gaaaatagta aaagagatcc
     1381 cgcattttga caggaaaacc cggcttgcgg atatgtatat agcttttgtt tgacagcaag
     1441 ggtttcattg tggcatttaa cataaggaag agagcctgtt tttatacatc gctctctttt
     1501 ttttataact tagcccccaa ttactaaatc gaagaacatg aaaaagactt ttttattagc
     1561 gatcgccttg ttgtgctttt gcgttccgat gagcttattc gcacaaaaac agcttgcttt
     1621 caaggatggg aaattcaaga tcgtccaatt tacagacatt cattgggatc agaaatcatc
     1681 taaatgcgct aagacagtcg ctacgataca atccgtatta aaggcggaga atccggatgt
     1741 ggcaatgctg acgggcgacg tggtgacagc aagccccggt ttggaaggat ggaagtcagt
     1801 gatcgggatc tttgaggagg ccaagatacc gtttacggtc atgatgggaa atcatgacgc
     1861 ggagatcgtc cccaaggacg agatttatgc catgcttagt aaatcacctt attttatggg
     1921 cgagaaggga ccgggtgata tccatggagc cggaaactat gtggtaccgg tctacagttc
     1981 ggacggaaag aaaccggcgg ccttattgta ttgtatcgac tccaacgatt atcctacgct
     2041 gaaggattat ggcacgtatg attggattca tttcgaccag atccattggt atcgtgagca
     2101 aagtatgcgc tataccaagg aaaatggcgg caaaccgttg cctgccttgg ccttttttca
     2161 tattcctctg ctggaatata atgagatcgt tggggcggag actacattag gacagaaaga
     2221 agagggaatc gcctctccca agatcaacac gggcttcttc gcttccttgg tggaaatgaa
     2281 ggatgtgatg gctactttcg ccgggcacga tcatgataac gattatatag gaatgttata
     2341 taatgtgggg ctagctttcg ggcgtgtatc cggatgggac gcttatggag atttcgagcg
     2401 gggtggccgt atcattgaat tgcgtgaggg caagtttgag tttgattcat ggattcgtac
     2461 cccgtccgga aaggaatata cgtattatta tccatctggc ctgacctcta aggatgagga
     2521 aacgatggaa ttcttacccg ccaaaacggt aaaacctaaa aagcacgggg tagtttatac
     2581 ctattatgaa ggtaaattta aacatacgga tcagatcgct tccgggacaa aagtgaaaga
     2641 gggtacgatg aaaaatatct ccattcagga ggctccggcc aaggatcatt tcgcttatga
     2701 gttccgtacg ttgataaata tccctgaaaa aggtgtatat cgcttttata cgtattcgga
     2761 tgatggttcc aaactattta tagacggtaa agctattgtt gataatgatg gctctcataa
     2821 tgctcgtata gcgaaaggaa aggtagcgtt agacgctggt ttccacgaat tacgtgtttt
     2881 gtatttcgag gattatatgg gcgaggcctt ggaggtcggg gtttcctgcc gtaaaataaa
     2941 ggaagctgtc ttaccagagg actggtatta tttaccggaa taaatatcca gttgtagaga
     3001 cgcagcatgc tgcgtctccc actgtctgat agtatcttag tcttgtacgg cagctttcgc
     3061 tttctctacc gcctcattga tattactgca aatattttct gcgccaatct tcttatcgaa
     3121 tccggatttt gtcaatacac ggtgtacatg ttcattgacc ccggaaagta tcatatggat
     3181 atgctctgcc tcggaaagac ggaaaagact ttccaagtta tgcagaccgg tagaatctat
     3241 gaacgaaacc ttacgcatac ggatgatgcg gactttcggt ttatctccca tacttttcat
     3301 gatgccgtcg aacttattcg ctacgccgaa aaagaacggg ccgtcgatct cgtacacctc
     3361 tacgccttta ggcagggaga ggacttcctc gtcatgatga atctcgccct cgtcggaaag
     3421 atcgatctca tccgtggtga cggatacatg cgtggtctcg gccacacggc gcataaagaa
     3481 taacatggcg atcaaaagac cgatctcgat agcgatcgta agatcaaaga taaccgtcag
     3541 gaagaaagtc accaacaaga cggatacgtc gcttttcggg tttttcatca aggaacggaa
     3601 cgtacgccac tcactcatat tataggatac gatgatcaat acgccagcca gacaagccat
     3661 tggaatgtgt ttggtaagcg gtccgaggaa aagcaagatc aataataata cgatggcgtg
     3721 aataataccg gcaaccgggg ttcgtccacc attatttata ttggtcattg tgcgggcgat
     3781 ggcgccggtc acgggaatac cgccaaaaat aggaacgatg atattcgccg cgccttgggc
     3841 gattagttcc gtattcgaat tatgcttgtc gcctgtcaca ccatccgcta ccgtagcgga
     3901 taataaagac tcgatagccc caaggatagc gatcgtaaag gcggagggaa gcaataagtt
     3961 gatagtttcc atattaaacg tgatcggagc cggggctggc aaggaagcgt taatagtaaa
     4021 ccggtctcca atcgtctcga tacctgtaat acccaaatga ttacgcataa tgtaaacaac
     4081 gatcgtcatg atgacgatag cgatcaagga acccggaatt ttcttcgtta gcctcggact
     4141 taacgtaatg atcaggatac taatgatacc gataacgaat gcccaagggt taaccgtatc
     4201 gaacgccccg aaatatgcga tccatttaga gatgaaatcg gcggggactt tatccatagt
     4261 caatccaaat aagtctttca tttgtgtcgt gaagatagtg atagcgatac cactcgtgaa
     4321 acctacgaca atcgggtagg ggataaactt aatcacggta ccgagcttca acacgcccat
     4381 caataccaga ataatacccg ctatgacggt agcgatggca agcccttcga tgccgaagtt
     4441 ctgtataatg ccataaacga tcacgataaa cgctccggta ggtccgccga tctgtacgtt
     4501 gcagcctcct aaaagggaga caatgaatcc accgataata gccgtgatca accctttctc
     4561 cggacttacc ccggaggcga taccaaaagc gatggcgagt ggtagggcaa ctatgccgac
     4621 aattataccc gccatgagat ccgtcatgaa cctctctttg gaataatttc tcagcgccgt
     4681 aaagagcttg ggctgaaaat caaatttgtt cttcattttt cttcttgcct gtttgatttg
     4741 aggatgcaaa gttaataaaa taaagaagat gcaaaaaatc taaagacgca ttccgatttt
     4801 gtgtaaacaa tttaggagga tttgttgttt cattgtataa aggaggagaa gtttttcctt
     4861 gataaataag tgatatctat ctcccgatag atattattta atgtttgcgt aatcgatgtt
     4921 tggaaacaaa ttcttacttt tgatcggtca taagaaaaac gatatacaaa acagactcat
     4981 taatttacta cataaaatta gcattatgga aaaaagtatt aaaggtacac gtaccgagca
     5041 gaatttattg aaatcattcg ccggagaatc tcaggcaaga agtcgttaca catttttcgc
     5101 tagcgtagcc aagaaagaag gttacgagca aatcgcaggt gttttcatgg aaacagccga
     5161 gcaagagaag gaacacgcta aacgtttctt taaattcttg gaaggtggaa tggttgagat
     5221 taccgcttct tatcctgcgg gcgtaatcgg aacaaccgct gagaacttgg ccgccgcggc
     5281 agctggtgag aatgaggagt gggctgaatt gtatcctgag ttcgctaaga tcgcagagga
     5341 agaaggtttc cccgctatcg ctgtagcttt caagatgatc gctaaggtag aggcagagca
     5401 tgagaatcgt taccgtaagt tattgaataa tgtagaaaca ggtacggtat ttgagaaagc
     5461 tgaggctatc ttgtggcaat gtcgcaactg tggtttcgta ttcgagggca agaaagctcc
     5521 ggttaactgt ccggcatgcg ctcatccgca agcttatttc gaaccgatga aacagaacta
     5581 ttgataatta aaagttgaga attgaaaatt gagaattact aactatgtta attctcaatt
     5641 ttcaattctc aattttcaat tatttaatcg gtgggtaatc aatcgtataa tgtaatcccc
     5701 ggctctcttt ccgttccatc gcttgacgag tgatcaaata acctacattg atcatattac
     5761 gcaactcaca taattcacgg gatgccttac aacgtttgaa aaggctctct gtctcctcat
     5821 ataaaatatc caaacggttc cacgcacgga tcaaacgtgt gttactacga acgataccta
     5881 catacgcttc catgatctgg tttacctctt tcatgctttg agtgatcaat acacgctctt
     5941 cattggtgat cgttccctca tcgttccatt ccggtacatc ttggttaaac tcatagcgat
     6001 ccatgacgct taatgagtgt tttgccgcag cgtcggcata tacaactgcc tcgatcaatg
     6061 agtttgaagc taagcggtta ccaccgtgca ggccggtaca agaacattct ccgatcgcat
     6121 ataggcgacg gatgctggat tgcccgttta agtctacctt gatacctcca cataaataat
     6181 gggccgcagg ggctaccggg atgtaatctt tcgtgatatc gatccctaag ctgaggcatt
     6241 tcttatagat attggggaag tgtttcttcg tctcttccgg atctttgtgc gtcacgtcca
     6301 aatagacatg gtcttcaccc cgttgtttca tctcgctatc gatcgcacgg gctacgatat
     6361 cacggggagc caaggaaaga cggggatcat atttatgcat gaactcctcg ccgccaaggt
     6421 ttctcaatac agctccatat ccgcgcatcg cctcggtgat gaggaaagag ggacggtcgc
     6481 ccggatgata caaggcggtc gggtggaact ggataaactc catatctttt acggagcctt
     6541 tcgcgcggta aaccatggcg ataccgtctc cggtagctac cagcgggttt gtcgtattcc
     6601 ggtaaacggc ctcacaaccg cctgtcgcca taacggttat ctttgacaag aaagtatgta
     6661 cctcgcccgt atcctcgttc aatacatagg caccgaaaca tttgataccg ggggtatggc
     6721 gggtgacgat aatgcccata tggtgctggg tgataatctc taccgcataa tggttcgtga
     6781 atacggtgat gttgggatgg ttgtttaccg tttctatcaa gctcgtctgt atctcggctc
     6841 ccgtattgtc ggcatggtgc aggatacgaa actcggagtg tcctccttct ttatgcagat
     6901 cgaattctcc gctttctttc ttatcgaaat taactcccca tcggataagc gcctcgatct
     6961 gggcaggggc ctcgcgcacg actttctcca cggctgcccg gtcgctgatc cagtcgccgg
     7021 cgatcatcgt gtcttctatg tgcttctcga aattatctac tttcaagttg gttacggaag
     7081 cgatacctcc ttgtgcgaaa tatgtgttgg cttcttcttg tccggcttta cagataagtg
     7141 ctacgctctt gccttcattg gctactttca gagcgaaact cataccggcg attcctgagc
     7201 ctatcactaa gtaatcgaat ctttgtacca tgttttctac tgtttaggct cacaaagtta
     7261 gggattaact gattaggttg ttccttttgc gcttgctttt cgtacaaaat aaatattgac
     7321 tacaggtttc ccggatagag ccttgcgggt tgtgttactg caacccggct tgcagtggag
     7381 gtctttagaa ttggacggat aatcccagcg tgaaggtacg ggctacagga tagatggaag
     7441 tggtctcgat accgggttct acgccattca cgttgatatt agcgggatcg cctccggtat
     7501 atccggtaag tgtaaataca ttatttaccg agaaatagca gcgtaacgat tgaatccatt
     7561 tattgtctgg gagagg
//
LOCUS       DBMDTB010000145         7241 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_2719_length_7241_cov_11.996359, whole genome shotgun sequence.
ACCESSION   DBMDTB010000145 DBMDTB010000000
VERSION     DBMDTB010000145.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 7241)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 7241)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7241
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2719_length_7241_cov_11.996359"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(154..1722)
                     /locus_tag="ACZPB4_15735"
     CDS             complement(154..1722)
                     /locus_tag="ACZPB4_15735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HIR1099703.1"
                     /translation="MNQTIYPIGIQNFEKIRKDGYLYIDKTALIYQLVKTGSYYFLSR
                     PRRFGKSLLLSTLEAYFQGKKELFEGLAMEKLEKEWTKYPILHFDLNISHYDAPDSLY
                     KILNDTLSRYEEEYGTRPTEETLPLRFAGIIDRAYRKTGQRAVILIDEYDKPLLQNLH
                     DEEMQNRFRNMLKPFYGVLKTMDRAIRFALLTGVTKFGKVSVFSDLNNLDDISMREPY
                     AAICGITETELRTHFDEDIHTLASALERTYEEARSLLRKRYDGYHFVAGGPGIYNPFS
                     LLNTFKYMRLSDYWFETGTPTYLVELLKRTNYDLYDMANTETDADVLNSIDSASNNPI
                     PVIYQSGYLTIKDYEPEFKIYRLGFPNQEVEEGFMKYLLPFYTNIQASKSPFEIGRFV
                     REVRAGDYDAFFHRLQSFFADTSYEAIIGRNPERDTELHYRNVLFIVFKLVGLYTQVE
                     YHTSNGRIDLVLQTDRYVYIMEFKLNGTAEEALRQIEEKGYALPFAGDDREVLKIGAN
                     FSSETRNIERWLVG"
     gene            complement(1856..3523)
                     /locus_tag="ACZPB4_15740"
     CDS             complement(1856..3523)
                     /locus_tag="ACZPB4_15740"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase family protein"
                     /protein_id="HIR1099704.1"
                     /translation="MSETITIYCKNNNTYKDVPIGSSLLDIYTALGAPLRYRPMNAQV
                     NNKTESLNFRCWQPKDIEFIDYTQLSGLRTYVRSLCHIFSKAVYDIWPTATLNLEHPV
                     SKGYYCVIHNGKNIDLETIERIKKRMWELIDADLPFLHKSVRTVDAAVLFRERGMNDK
                     ARLIETAGLPYTSYYELEGYINFFYGCLTPSTGYIQLFDLEPYMDGVLLRIPKQTDPM
                     ELQPVIKQDKMFEAYKEHLTLQRTVGLDNVGDLNLAIEKGRSQDIILVSEAMQEKQVA
                     KIAEKIADGYKEGIRIVLISGPSSSGKTTFCKRLQVQLTTNLLHPVGISLDDYFLNRE
                     DTPKDEHGEYDFESLYALDLPYFNKDLKKLLSGEEIDLPTFNFETGQRVFKGKKLKLR
                     ENSILVIEGIHALNPELTEFIDDKYKYRVYVSVLTSISLDNHNWIPTTDNRLLRRIIR
                     DYRFRGYSAEDTINRWPSVRRGEDKWIFPYQENADAMFNSAMLYELAALRKFAEPILA
                     QVPESSKANAEAYRLLRFLRYFNYIPTEELPGTSLLREFLGGGSFKY"
     gene            3607..5292
                     /locus_tag="ACZPB4_15745"
     CDS             3607..5292
                     /locus_tag="ACZPB4_15745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005436 - sodium:phosphate symporter
                     activity [Evidence IEA];
                     GO_process: GO:0044341 - sodium-dependent phosphate
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HIR1099705.1"
                     /translation="MDYSFFDFLRLIGSLALFLYGMKIMSEGLQKFAGDSLRRILTAM
                     TTNRVTGVLTGVLITALIQSSSATTVMVVSFVNAGLLTLTQSIGVIMGANIGTTVTAW
                     LISALGFKVDIAAFALPLLAFALPLFFSGKSSRKSIGEFVFGFAFLFMGLQSLKANAP
                     DLGANPEMLAFVQNYTDMGFFSIILFLFIGAILTMIVQASAATMAITLIMCANGWIDY
                     HLGVALVLGENIGTTITANLAALTGNTQARRAALAHLVFNVFGVMWVLVLFYPFTNAV
                     SWFVTHVMKVSDPAVAVSFKLAAFHTAFNISNTFIMIWFVSLIEKTVCTLIKPKVEDE
                     EYRLRYITGGMLSTAELSILQAHKEISLFAERTARMFNMVKELFYEKNEETFLKTYSR
                     IEKYENISDRMEIEIANYLTEVSEGRLSSESKEEIRIMLRAVSEIESIADSCNNLARS
                     IKRRNEFKSEFTEEQNKHLDHMFELVSGALNRMNLILHKPELVHDDINPSYNIENEIN
                     NYRNQLKSRNIEDINNKLYQYQDGVYYMDMVSESEKLGDYVLNVVQAVIEKKI"
     gene            5369..6751
                     /locus_tag="ACZPB4_15750"
     CDS             5369..6751
                     /locus_tag="ACZPB4_15750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S41 family peptidase"
                     /protein_id="HIR1099706.1"
                     /translation="MNYKYYTIVILGLLAFSACEKDDIDIPATDNEVNQWIEQTMREN
                     YLWYSEFPDKSSLDFSLDPESFFKGLLSYKDGKDLPEGHHYFSLLEKATVTKSIYDAN
                     NSYGFDFATSNLKDGGSTYKIAIVLYVLKDSPAEEAGLKRGDWILGVNGSLGSIQDYD
                     VLRSGGSVSLQLGKEIGNTKGFVSTRRVTLNASRTVEDTPFLKDSVYTYGNKRIGYLM
                     YNHFASGPDEYDYSDTSYNLYLQQLFEKFKSRNVNEFVLDLRYNGGGLVNCAQLLASL
                     LVRENVLGEPLCIMEYNDKNSNKNETLPLLKTTEVMAGNLNLQRLFVLTGSATASASE
                     LIINSLRSYLDVRVIGKQTFGKTVGMTIYNESKKYGWILSPVTFHIYNKDREADYEDG
                     FHPDVAIDEFKSDLAEFGDLKDPLLGQAIYEITGQSPLLRSATPRGNREIQYNPPLSY
                     KDNLLLIPKD"
     gene            6763..>7241
                     /locus_tag="ACZPB4_15755"
     CDS             6763..>7241
                     /locus_tag="ACZPB4_15755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HIR1099707.1"
                     /translation="MESTFLKIINAKVLTPSGLLPNGQIIISDGKIVEITGQNREIPH
                     AEIIDAKGYYVAPGCIDTHVHGGNGHDFTEATPKAFYAITRAHALQGTTALYPTLAAA
                     PIETFREAIKTCEHIMNHPEQGARIMGLHLEGNYLNMAMKGGQDPNYIYPPDPQEYK"
BASE COUNT         1971 a         1716 c         1643 g         1911 t
ORIGIN      
        1 cagttaacgg cttgggaagt gatcagttat tcacttgaga agccttttcc cagagaagat
       61 atacttactt tgccgatgaa gtatatcttc tccgggcata gaatatatac tgcgttggcc
      121 aagtaagtat atatggataa aaataggact ttttcaccct accagccacc tctcgatatt
      181 ccgggtctcg gaggagaaat tcgcgccgat ctttaagacc tcccggtcgt ctccggcgaa
      241 gggtagggca taacctttct cctcgatctg ccgcagagcc tcctctgcgg ttccgttcag
      301 cttgaactcc ataatataga cgtagcggtc ggtttgtagg acgaggtcga tgcgtccatt
      361 cgaggtgtgg tattccactt gcgtgtacag tccgaccagc ttgaagacga tgaagagcac
      421 gttgcggtaa tgcagctccg tgtcccgttc cgggttccgg ccaataatcg cctcgtaaga
      481 ggtatcggcg aagaagcttt gtaggcggtg gaagaaggcg tcgtagtctc ctgcccgtac
      541 ctctctcaca aagcggccta tctcgaaagg agacttcgag gcttgaatgt tcgtatagaa
      601 cggcagtaag tatttcatga aaccctcctc tacctcttgg ttggggaaac ctaagcgata
      661 gatcttgaat tccggctcgt aatccttgat cgtgaggtat ccgctttggt agatgacggg
      721 gatgggattg ttcgaagcgg agtcgatgct gttcaacacg tcggcgtcgg tctcggtgtt
      781 ggccatgtcg tacaggtcgt aattcgttcg tttcagcaac tccaccaagt aagtgggcgt
      841 gcccgtctcg aaccaataat cgctgagccg catatacttg aaggtattca gcaggctgaa
      901 agggttataa atacccggtc ccccggccac gaaatgatag ccgtcgtacc gtttccgtag
      961 caaggatcgg gcctcctcgt atgtccgctc aagggcagag gccaacgtat ggatgtcctc
     1021 atcgaaatgc gtacgcagct ccgtttccgt gatgccgcaa atggcggcgt aaggctctcg
     1081 catggatata tcgtccagat tgttgaggtc gctgaagacg cttaccttcc cgaacttggt
     1141 cacgccggtc agtagggcga agcgtatagc cctgtccata gtcttcaaca caccgtagaa
     1201 gggtttgagc atgttccgga accggttttg catctcttcg tcgtgcaagt tctgtagcaa
     1261 gggcttgtcg tactcgtcga tcaggatcac ggcccgctgt ccggttttgc ggtaggcccg
     1321 gtcgatgatt ccggcgaagc ggaggggcag ggtctcctcg gtaggccgtg tcccatactc
     1381 ctcctcatat ctggacaagg tatcatttaa tatcttatac aagctgtcag gggcgtcgta
     1441 gtgggagata ttcaagtcga aatgcaagat cggatacttg gtccactctt tctccagctt
     1501 ctccatggcc agtccctcga acagctcctt tttcccttgg aaataggcct ccagcgtgga
     1561 tagcagcaga ctcttcccga atcgacgcgg gcggctgagg aaatagtagc ttcctgtttt
     1621 caccaattga tagatcaagg cggtcttatc aatgtagaga tagccgtcct tgcggatctt
     1681 ctcgaagttc tgtatgccga tggggtaaat agtctggttc atatcgtctt gtgtttaatg
     1741 tgactcatag acaaagatat gaaaaaaaca cgtacatgtt ttcaaaaaaa gacgtacatg
     1801 ttttcggaaa aacacgtacg tcttttttta aaggctttat agagtatgat tctacctagt
     1861 acttgaagct tcctcccccc aagaattcac ggagcaagga agttccggga agttcctccg
     1921 tcgggatgta attaaagtag cggaggaaac ggagcaaacg atacgcctcc gcattcgcct
     1981 tactactctc cggcacttgc gcgaggatcg gttccgcaaa tttgcgcaag gcggccagct
     2041 catacaacat ggcgctgtta aacatagcgt ccgcattctc ctgatacgga aagatccatt
     2101 tatcctcacc ccggcgaacg ctcggccaac ggttgatcgt atcttccgcc gaatatcccc
     2161 taaagcgata atcccggatg atacggcgca gcagacgatt atccgtcgtc ggtatccaat
     2221 tatggttatc caaagagata gaggtcaaga ccgagacata tacccgatat ttatatttat
     2281 catcgataaa ctccgtcagc tccggattca aggcatggat accttctatc accaagatcg
     2341 agttctcacg aagcttaagc ttcttccctt tgaaaacccg ttggccggtc tcgaaattaa
     2401 aagtcggcaa atcgatctct tccccggata acaacttctt caaatcctta ttaaaatagg
     2461 gtaaatccag cgcatacaag gattcaaaat catactcgcc atgctcatcc ttcggtgtat
     2521 cttcccggtt caagaaataa tcatccaagg aaattcctac cggatgaagc aggttagttg
     2581 ttaattgcac ttgcaaacgc ttgcaaaacg tagtctttcc cgaagaagaa gggccagaga
     2641 tcaagacgat acggatgccc tctttatatc catcggcgat cttttcggcg atcttagcaa
     2701 cctgtttttc ctgcatcgcc tcagagacaa ggattatatc ctgagagcgg cctttctcta
     2761 tcgctaaatt caaatccccc acattatcta agccgacagt ccgctgcaat gtaaggtgtt
     2821 ccttataagc ctcgaacatc ttatcctgct tgatgacagg ctgcaattcc atcggatcgg
     2881 tctgcttcgg aatacggagc aaaacgccat ccatatacgg ttccaagtca aacaattgga
     2941 tatagccggt cgaaggggtt aaacagccat aaaagaagtt gatataacct tccaactcat
     3001 aataagaggt ataaggcaat cccgccgtct ctattaagcg agccttatca ttcatacccc
     3061 gctccctgaa caatacggcg gcatccaccg tacggacact cttatggagg aaaggaagat
     3121 ccgcgtcaat caactcccac atacgtttct tgatcctctc gatcgtctcc agatcgatgt
     3181 tcttgccgtt atggatcacg caatagtaac ctttcgacac cggatgttcc agatttaagg
     3241 tcgccgtcgg ccaaatatca tacaccgcct tggaaaatat atggcaaagc gagcggacat
     3301 aggttctcaa tccggataat tgagtatagt cgataaattc gatatccttc ggttgccagc
     3361 aacggaagtt caagctttcc gtcttattat tcacttgcgc gttcatcggc ctgtaccgaa
     3421 gcggagcgcc aagcgccgta taaatgtcca acaacgaaga accaatgggt acatccttgt
     3481 aggtattatt atttttgcag taaattgtta ttgtctcaga catactatct cagttattat
     3541 ttgtaaattc gccccctaaa gttaggaata ttaatcggat atacaatcca cttaaacgta
     3601 atttaaatgg actattcttt ttttgatttt ctccggctga tcggctcctt ggcgctgttc
     3661 ttgtacggaa tgaagatcat gagtgaaggg ttacaaaaat ttgcgggtga cagtttacgt
     3721 cgaatactaa ccgcgatgac cacaaacaga gtgaccggtg tgctcaccgg cgtgttaata
     3781 acggctctca tccaatcctc atcggctacg acggttatgg tcgtgagttt cgtgaatgcc
     3841 ggactcttga cattgaccca atccatcgga gtcattatgg gtgccaacat cggaaccacg
     3901 gtaacggcat ggcttatctc cgccctcggt ttcaaggtcg atatcgccgc attcgccctt
     3961 ccccttttag ctttcgctct cccactcttc ttctcaggaa aaagctctcg taaatcaatt
     4021 ggtgaatttg tctttggttt cgcgttcctg ttcatggggc ttcaaagctt aaaggcaaac
     4081 gccccggacc tcggagcgaa tccggagatg ctggctttcg tgcagaatta tacggatatg
     4141 ggatttttct ccatcatctt gttcttattt atcggagcga tcttaaccat gatcgtacaa
     4201 gcctccgctg ccacgatggc tattacattg attatgtgcg ccaacggctg gatcgattat
     4261 catttgggag tcgctttggt attaggcgag aatatcggaa ccacgattac ggccaactta
     4321 gccgcattaa ccggaaacac acaagcacga cgagccgcat tagcgcacct tgttttcaac
     4381 gttttcggtg tcatgtgggt tttggtgctc ttctaccctt tcacgaatgc cgtctcatgg
     4441 tttgttaccc atgtaatgaa ggtcagtgat ccggctgtgg cggtatcctt taaactggca
     4501 gcgttccaca cagcattcaa tatcagtaat actttcatta tgatctggtt cgtaagcttg
     4561 atcgaaaaga ccgtatgtac gcttatcaag cccaaggtgg aagacgagga ataccgcctt
     4621 cgctatatca cgggaggtat gttatccacc gccgagcttt ctatcctgca agcgcataaa
     4681 gaaatctcat tattcgccga gcgtacggct aggatgttta atatggtgaa agaattattc
     4741 tacgagaaga atgaggagac cttcctcaag acttatagcc gcatcgagaa atacgagaat
     4801 atcagcgacc gcatggagat cgagatcgca aattacttga ctgaagtatc ggaaggccgt
     4861 ttgagttctg aaagtaagga agaaatccgt atcatgctac gtgccgtctc ggaaatcgag
     4921 agtatagcgg attcttgtaa taaccttgcc cgaagtatca aacgcagaaa cgagttcaaa
     4981 tccgaattca cggaggagca aaacaagcac ttggatcata tgttcgaact ggtatccggg
     5041 gcgttaaatc gcatgaacct aattttgcat aaaccggaac tcgtacatga tgatatcaat
     5101 ccttcttata acatagagaa cgagatcaac aactatcgta accagttgaa gagccggaat
     5161 atcgaagata tcaacaataa gctgtaccaa tatcaagatg gcgtttatta catggacatg
     5221 gttagtgaaa gtgaaaagct gggcgattat gtattaaatg ttgttcaagc ggttatcgag
     5281 aagaaaatat agcgtatatt tgtccttaac aatatcaaca gcccttttcc gttattgaga
     5341 gaagggctgt ttttaatata tatccactat gaattataag tattatacga tcgttatcct
     5401 tggcctttta gcattctccg cttgcgagaa agatgatatt gacattccgg caaccgacaa
     5461 tgaagtaaat caatggatcg agcaaacgat gcgagagaat tatctttggt attccgagtt
     5521 cccggataaa agttccttgg actttagtct tgatccggag agcttcttca agggcctgtt
     5581 atcctataaa gacgggaaag atcttcctga aggtcatcat tacttttccc tattagagaa
     5641 agcgaccgta acaaagagca tttacgacgc gaacaactca tatggattcg atttcgcaac
     5701 ttccaacctt aaagacggag gcagtaccta taaaatagcc attgtccttt atgtattaaa
     5761 ggattcaccc gccgaagaag ccggattgaa acggggagac tggatacttg gcgtaaacgg
     5821 ctccttgggt tctatccaag actatgatgt gttgagaagc ggaggcagcg tatccctcca
     5881 actaggaaaa gaaataggaa acaccaaggg attcgtctcc acccgaagag ttaccttgaa
     5941 cgcatcccga acggtagaag acaccccatt cctaaaagat tccgtataca catatggcaa
     6001 taagcgaatc ggctatttga tgtacaacca tttcgcctcc ggaccggatg aatacgatta
     6061 tagcgacaca agttataatc tttatttgca acaactcttc gaaaaattca aaagccgcaa
     6121 cgtcaatgag ttcgtacttg atttacgcta taatgggggt gggcttgtca attgcgccca
     6181 attactggct tcgctattag tccgtgaaaa cgttttagga gaacctttat gtatcatgga
     6241 gtataacgat aaaaactcca ataaaaatga gaccttgcct ttgctcaaaa cgaccgaggt
     6301 catggcggga aacttaaacc tacaacggct atttgttttg acaggttcag ctacggcttc
     6361 tgcctccgaa cttatcatta actcgctacg atcttatcta gacgttcggg ttatcggtaa
     6421 gcagactttt ggcaagaccg tcggtatgac gatctacaat gaatctaaaa aatatggctg
     6481 gatactttct cccgtcactt tccatattta taataaggat cgggaagctg attatgaaga
     6541 cggatttcat cccgatgtag ctattgatga attcaagagt gatctagctg aattcggaga
     6601 tttgaaggat cctttattag gacaagctat ttacgagata accggccagt caccactctt
     6661 acgatccgct accccgaggg gcaaccggga aatccaatat aatcccccgt tgtcctataa
     6721 ggataactta ttactgattc caaaagacta aaaacaagat atatggaaag cacatttctt
     6781 aaaatcataa acgcaaaagt attaactcct tcgggcctcc taccaaacgg gcaaatcatc
     6841 atctcggatg ggaaaatagt ggagatcacc gggcaaaacc gggagattcc tcatgcggag
     6901 atcatcgacg caaaaggata ttatgtggct cccggctgta tcgacacgca tgtacacggc
     6961 ggcaacggac atgatttcac ggaagctacc ccgaaagcgt tctatgcgat cacaagagca
     7021 catgctttac agggaacaac ggctttatat cctacattgg cagctgcccc tatcgagacc
     7081 ttccgggaag cgatcaagac ctgcgagcac atcatgaacc acccggaaca gggggcccgt
     7141 atcatgggat tacatctcga aggcaactat ttgaatatgg ctatgaaagg cggacaagac
     7201 cctaattata tttacccgcc cgatccccaa gaatataagg a
//
LOCUS       DBMDTB010000146         7205 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_2735_length_7205_cov_8.778153, whole genome shotgun sequence.
ACCESSION   DBMDTB010000146 DBMDTB010000000
VERSION     DBMDTB010000146.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 7205)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 7205)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7205
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2735_length_7205_cov_8.778153"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..166)
                     /locus_tag="ACZPB4_15760"
     CDS             complement(<1..166)
                     /locus_tag="ACZPB4_15760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase"
                     /protein_id="HIR1099708.1"
                     /translation="MKHVILTIVLLLASGLVIAQTKMSDQLSKTTRMNTQSEIYFAGG
                     CFWGTEHFMKQ"
     gene            complement(226..1251)
                     /locus_tag="ACZPB4_15765"
     CDS             complement(226..1251)
                     /locus_tag="ACZPB4_15765"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HIR1099709.1"
                     /translation="MEYRVLGLSGLRVSTIGLGCMGMSHAYGAPADRKEMTELLALAV
                     DMGYTFFDTAEVYGTNTNPHDNEELLGDALKPFRDKIVIATKFGLTFDKSSECGPYPL
                     IPNSKPKSIRLAVEGSLARLKTDHLDLYYQHRIDPQVEPEEVADTMAYLIKEGKVLHW
                     GISEAGEDYIRRAHKVCPITAIQNRYSMMARWHENLFPSLEELGIGFVAFSPLANGLL
                     SACYDVKSVFNPQNDYRATMPQFKKESFERNKPLLDLINHLADEHHATPAQISLAWML
                     QKKPWIVPIPGTRHLCRLKENAGAVDIKINPAEINQIDTALDHMDMSEVFGGTKIKQQ
                     PILRMKA"
     gene            1432..2466
                     /locus_tag="ACZPB4_15770"
     CDS             1432..2466
                     /locus_tag="ACZPB4_15770"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HIR1099710.1"
                     /translation="MKSKIIVALLIMNMVISASAQNQNQYGLVYRDAISENVVGKVTI
                     HPVSYEVGGIGVVANIYTPANYDSSKEYVAIVIAHPNGGVKEQVAGLYAQRLAELGYI
                     TIAADARYQGASGGEPRNTDRPPNRIEDIHGMVDFISQYPGVDASRIGALGICGGGGY
                     TLGAAQGDKRIKAVATLSMFNSGRVRRNGFQDSQINTIQQRLTQAAEARNEEAKGKVL
                     YTGEMNISDEEAAKLPFALYRDGYEYYFKTHAHPNSTFRYTMSSLLDLMTWDATDHID
                     LIDQPLLLIAGSDADTKYMSDEAFEKATGTKDKEMYLIPGAEHIKTYFVPEYVNLAVN
                     KMKDFFGMKL"
     gene            2503..3312
                     /locus_tag="ACZPB4_15775"
     CDS             2503..3312
                     /locus_tag="ACZPB4_15775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIR1099711.1"
                     /translation="MKYDKDSVIISDSLNGLGTDIYKEYLSHALCLGGACKFEFNGNP
                     FELHEGDCMIVRKGKLVEKITPSADFKVKVIYVTPQFIELCTPQNNYGMKGQLSLFLN
                     PVMRLDREQQDICKKDFENIEYRFNNENHNFYRDIMINVIQTMILDFFDFHSHIYGEE
                     KISAQYASIMSKFLQMLEDGVYRQHRDVTYYASELCVTPKYLSEVTKKVSGYAANYWI
                     NRYTILDISRLLRDKSLSFVYISDLFGFSSPSYFSRYVQHNLGIKSSDYRE"
     gene            3493..3945
                     /locus_tag="ACZPB4_15780"
     CDS             3493..3945
                     /locus_tag="ACZPB4_15780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HIR1099712.1"
                     /translation="MRSLFIATLLLVSMGMGAYAQETKKTFTPEQQEMIDLSNAKWKW
                     MSEKDVDKLDALFHENSMFVHMGGSWGKQPELDVIRTGNIHYKHAEIHDVDVKFAGCA
                     GIVYSRIHLNSVVGGREVRFPFIVTETYVKEDGQWKLATLAFTRTVGE"
     gene            3958..5109
                     /locus_tag="ACZPB4_15785"
     CDS             3958..5109
                     /locus_tag="ACZPB4_15785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing carboxymuconolactone
                     decarboxylase family protein"
                     /protein_id="HIR1099713.1"
                     /translation="MNMRQNFLIRLFCLCLFPVFTMAQNMDNFRQPYPLGTKLPEASA
                     KNFIGQAYIAPITVNRELNVPMSNVTFEPRCRNNWHYHKGGQILVASAGIGYYQEKGK
                     PARRLYPGDIVEIAPDVIHWHGAAPDSWFAHVAVSCNPQTNEAVWLSPVGEKEYQEAT
                     SQAENVYAEANRVLEAREQAIVSIAAYTGKGDLAHLRQALVKGLESGMTVNEVNEVLI
                     HAYAYCGFPRSLRAIQTFMQVIEERKSMGIKDVEGREASAIEDGGSRYERGRDILAEI
                     SGTSASVPKTGYAVFAPTIERFLKEHLFADLFERDLLTYRERELATVSVLAGVGGVEP
                     MAYGHMSICLHLGITPEQLTALLNIVEINLGKKSSDPLRDVLGQLTDKK"
     gene            5121..6179
                     /locus_tag="ACZPB4_15790"
     CDS             5121..6179
                     /locus_tag="ACZPB4_15790"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HIR1099714.1"
                     /translation="MKKILLLALLIPVFGMADAQDLVIAKQGHFSVGGQTIQRPGTYD
                     NSKFVGWATQVETGQSYRADHAFVDFQVPAHAKKLPLVYVHGYGGSGICWQMTPDGRD
                     GFATLMLCRGYSSYVMDLPGRGRAGRTSATTTVKPLADEMFWFDIWRIGIWPEYNKGV
                     QFPSDSAYLSQFFREMTPDISDHKQDVPAINALTEKIGDNILVTHSAGGFPGWMAAIQ
                     NPNVKAVVSYEPGGYVFPEGEVPDPIAGLTGGAAGVAIPMEQFLRLTRIPIVMYFGDY
                     IPETPSENLGGENWRVRLQMGRKFVEAINRHGGNATLVELPKIGIYGNTHFLMQDLNN
                     GQLADLLGEWLEKNDLGK"
     gene            complement(6232..6543)
                     /locus_tag="ACZPB4_15795"
     CDS             complement(6232..6543)
                     /locus_tag="ACZPB4_15795"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MGMT family protein"
                     /protein_id="HIR1099715.1"
                     /translation="MKADFYTEVYNIVREIPEGCVVTYGQLAKLARRPQCSRMVGQAM
                     FNVPKELNLPCHRVVNSQGRLAPNWAEQRGLLEKEGITFKKNGCVDLKKHIWEDILPI
                     I"
     gene            complement(6533..7078)
                     /locus_tag="ACZPB4_15800"
     CDS             complement(6533..7078)
                     /locus_tag="ACZPB4_15800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF169 domain-containing protein"
                     /protein_id="HIR1099716.1"
                     /translation="MDIQTFINNYYEAFSLKAESPIAFWYSDSLLGELKQTQGCLFKA
                     LPAIRQGEIIRYLHFARIDRLTSFEKVEGLLFLATPDILSGLITWTFFDNNNPDAVST
                     PFGSGCSSTITLTVNENRQGGHRTFLGFFDPSVRPYVESNLLSLTIPMSRFKTMYQTM
                     RNSSLYETHAWAKIKTRINEG"
     gene            complement(7106..>7205)
                     /locus_tag="ACZPB4_15805"
     CDS             complement(7106..>7205)
                     /locus_tag="ACZPB4_15805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004296142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HIR1099717.1"
                     /translation="SPRSAEYGFFGCKHFSKANDFLRGKGIPEIDW"
BASE COUNT         1968 a         1401 c         1777 g         2059 t
ORIGIN      
        1 tttgcttcat gaaatgttct gttccccaga aacatccacc ggcaaaataa atttcacttt
       61 gggtattcat tcttgttgtt tttgaaagtt gatcactcat ttttgtttgt gcgattacta
      121 aaccgcttgc caatagcaaa acgattgtca aaattacatg tttcatctta tatatttgta
      181 gttatataac ctaaataata agaaaatggt ttcaactaaa agtggtcatg ccttcatgcg
      241 gaggattggc tgttgtttga tctttgtccc accaaacacc tcgctcatat ccatatggtc
      301 aagagccgtg tctatctgat tgatctcggc gggatttatc tttatatcca cagcccccgc
      361 attctctttt agccggcaga gatgacgagt tccgggaata ggaacgatcc acggcttttt
      421 ttgtagcatc caagctaggg atatttgtgc gggagtagca tgatgctcat cggccagatg
      481 gtttatgaga tctagaagag gcttgttcct ctcgaaactt tcttttttga attgcggcat
      541 agttgcccgg taatcatttt gagggttgaa tacgcttttg acatcatagc aagcagaaag
      601 taaaccgttt gccaatggcg agaaagcaac gaagccaatg cctaattctt ctagagaggg
      661 gaaaaggttt tcatgccaac gtgccatcat ggaataacga ttttgtatgg cggttatagg
      721 acagacctta tgcgcacggc gaatatagtc ctcgcccgcc tctgatatac cccaatgcaa
      781 tactttgcct tccttgatca agtaggccat cgtgtcagct acctcttccg gttctacttg
      841 gggatctatg cgatgctgat agtaaaggtc aagatggtct gtcttaagtc tggctaaaga
      901 gccttccacg gctaaacgaa tcgacttcgg tttagaattc gggataaggg gataaggacc
      961 acattcgcta gacttatcaa aagtgagtcc aaacttagta gcgatcacga ttttatcacg
     1021 aaatggcttt aaggcatcgc ctaaaagctc ctcattgtca tgaggattcg tgtttgtacc
     1081 atatacttcg gccgtatcga agaaggtata tcccatatca acagcgaggg ctaacaattc
     1141 cgtcatctct tttctgtcgg caggcgctcc ataagcatgg ctcataccca tgcaacccaa
     1201 tcctatagtg gagaccctaa gtccgcttaa tcccaaaact ctgtattcca tatttattta
     1261 tattttatct gagcgcaaag ttgggaagaa gtatctccac cggtgtaaca acaattgcgg
     1321 atataaatac aattatttcg gttttctgta aaaatggtga tacaatccgt aatctgtatt
     1381 cattctgtat gattgggtaa atgtatctta gcggtcaaaa aataatagaa tatgaagagt
     1441 aaaattattg tagctttatt aattatgaac atggtaataa gtgcttccgc acaaaatcag
     1501 aatcagtatg gattggtata tcgcgatgcg ataagtgaaa atgtggttgg aaaagtaact
     1561 atacatcctg tctcgtatga ggttggaggt ataggggtag tggcgaatat ctatactcct
     1621 gcgaattatg attcctcaaa agagtatgta gctattgtta ttgctcatcc taatgggggc
     1681 gtgaaagaac aagttgcggg tctctatgcg caacggctgg cagagcttgg atatataact
     1741 atcgctgccg atgcgcgtta tcaaggagca agtggtggtg agcctcggaa tacggatcgt
     1801 ccgcccaacc ggatagaaga tattcatggt atggtggatt tcatatctca atatccgggt
     1861 gtagatgcca gtcgtatagg tgcgcttggt atttgtggcg gtggaggtta cacgcttggg
     1921 gctgcacagg gtgataaacg tataaaggcg gtcgctacac tcagcatgtt taattcgggg
     1981 cgtgtacgtc gtaatggttt tcaggattcc cagataaata ccatacaaca acgtttaacc
     2041 caagcggccg aggctagaaa tgaagaggcc aaaggcaaag ttctatacac gggtgagatg
     2101 aatatctccg atgaggaggc ggcgaaactc ccgtttgccc tatatcgtga tggttatgag
     2161 tattacttta aaacccatgc tcatccgaat tcgacatttc gctataccat gagcagttta
     2221 ttggatctta tgacttggga tgctacggat catatcgact tgatcgacca gcctttgcta
     2281 ttgatcgccg gaagtgatgc cgatacaaaa tatatgtctg acgaagcttt tgaaaaggct
     2341 accggaacaa aagataaaga gatgtatctt attccaggag cggagcatat caaaacttat
     2401 tttgtcccgg aatatgtgaa tctagcggta aataaaatga aagatttctt cgggatgaaa
     2461 ttgtaatttg attaaatttg tacgatctaa aatgggggta tcatgaaata tgacaaagat
     2521 agtgttatta tctctgatag tctgaatgga cttgggacag atatttataa agagtacctg
     2581 tctcatgcct tgtgtttggg tggagcatgt aaattcgagt tcaatggaaa tccattcgag
     2641 ttacatgaag gagattgtat gattgtgcgt aaaggaaaac tggttgagaa gatcaccccc
     2701 tccgcggatt ttaaggttaa agtcatttat gtcactcccc aattcattga gctttgtact
     2761 ccccagaata attatggaat gaaaggccag ttatctttgt tcctgaatcc tgtgatgcgt
     2821 ctggatcgcg agcaacagga tatctgtaag aaagatttcg agaatataga gtataggttt
     2881 aacaatgaaa accataattt ttatcgtgac ataatgatta atgtgatcca gacaatgatt
     2941 ctggatttct tcgattttca ctcacatatt tatggggagg agaagatctc ggcccaatat
     3001 gcctccatta tgagtaagtt cctgcaaatg ctggaagatg gggtttatcg ccaacatagg
     3061 gatgttactt actatgcctc ggaattatgc gtgacgccga agtatttatc ggaagtgacg
     3121 aaaaaggtga gtggctatgc agcaaattat tggattaacc gttatacgat attggatata
     3181 tcacggcttt tgcgtgataa gtcattatct ttcgtttata tttccgattt gtttggtttc
     3241 tcttctccct cttatttcag ccgttatgtg cagcataatt taggtataaa gtcctcagat
     3301 tatagggagt gaccttgtaa gctagcttca ctcctttcct tttcggtaaa atttgtagtt
     3361 gacaccgact tttttgtatt gtctcaaaac tcctttggtc gtaacttcgc aacgaggaat
     3421 aggtataaat agatgatgga aaactattta tatataatgt ataatcaaat taataaagcc
     3481 atgcaaaaaa ttatgagatc attatttatc gcgacattgt tgttggtatc gatgggaatg
     3541 ggtgcctatg cgcaggaaac aaaaaagaca tttactccgg agcagcagga gatgatagat
     3601 ttgtctaatg cgaaatggaa atggatgtca gaaaaagatg tggataagct cgacgccctc
     3661 ttccacgaga actctatgtt tgtacatatg ggtggttcgt ggggtaagca gccggagctt
     3721 gatgtgatcc gtacgggaaa catacattac aagcatgcgg agatacatga tgtagatgtt
     3781 aaattcgccg gttgcgccgg aatcgtatat agccgtattc atcttaattc ggtagttggt
     3841 ggtagggagg tcaggttccc tttcatcgtg actgagacgt acgtgaagga agacggacaa
     3901 tggaaacttg ctaccttagc atttactcgt acggtaggag aataatgata aatacatatg
     3961 aatatgagac agaactttct aatccggctt ttctgcctat gtttgttccc ggttttcacc
     4021 atggcgcaaa atatggataa tttcagacaa ccgtacccct tgggtactaa gttgccggaa
     4081 gcgtccgcga agaacttcat tggtcaggcg tatatcgctc cgattacggt taatagggag
     4141 ctgaatgtcc caatgtctaa tgtcactttt gagcctcgtt gccggaataa ctggcattat
     4201 cataaagggg ggcagatact tgtcgcgtca gcaggcatag gctactatca ggaaaagggg
     4261 aaaccggcca gaagattgta tccgggggat atcgtggaaa ttgcgcctga cgtgattcac
     4321 tggcatgggg cggctccgga tagctggttt gctcacgttg ccgtaagttg caatcctcaa
     4381 acgaatgagg cggtgtggct cagtccggtg ggagagaagg aatatcaaga agcgacaagc
     4441 caagcggaga atgtgtatgc cgaagcaaac cgggtattgg aagccaggga acaagccatt
     4501 gtctctatcg cggcgtacac gggcaaggga gacttggcgc atctgagaca ggcgcttgtg
     4561 aaaggacttg aatccggtat gaccgttaat gaagtaaacg aagtactaat acatgcctat
     4621 gcttattgtg gatttcctcg cagcttaaga gccatacaga catttatgca agtcattgaa
     4681 gagagaaaaa gcatgggaat taaagatgta gagggtcgtg aagcctctgc tatcgaggat
     4741 ggtgggagtc gatatgagcg gggacgggat attctggcgg aaatatcggg tacgtctgct
     4801 tctgtcccta aaaccggata tgcggtattt gccccgacga tcgaacgttt cctcaaggaa
     4861 catctgttcg cggacctttt tgagcgcgac ttattgacat atagggagcg tgaattggcg
     4921 accgtgtctg tattggcagg cgttggcggt gttgaaccta tggcttacgg ccatatgtca
     4981 atttgcttgc atctgggtat tacgccagag caacttacgg ctttgctaaa tatcgtagag
     5041 ataaacctag ggaaaaagag ttcagatcca ttacgtgatg tgctcggaca attaacggat
     5101 aaaaaatgaa tcagaagaat atgaagaaga ttttattatt agcattatta atacccgtgt
     5161 ttggaatggc agatgcccag gatttagtga tcgctaaaca agggcatttc tcagtaggag
     5221 gacaaaccat acagcgtccg ggtacgtatg acaacagtaa gtttgtcggt tgggctaccc
     5281 aagtcgagac cgggcagagc tatcgtgcgg atcatgcttt cgtagatttc caagttccgg
     5341 cccatgcgaa aaaattgcct ttggtttatg ttcatggtta tggtggctct gggatatgtt
     5401 ggcaaatgac acccgatggg cgggatggtt tcgctactct catgttatgc cggggatata
     5461 gcagttacgt gatggatctt cccggtcgtg gccgtgccgg aaggacatct gctacgacta
     5521 cggtcaagcc gctggccgat gagatgttct ggtttgacat ctggcgtatc gggatttggc
     5581 cggaatataa caaaggtgtg cagtttccgt ctgattcagc ctatctatcg cagtttttcc
     5641 gggagatgac gcccgatatc agtgatcaca aacaagatgt accggcaatc aatgccttga
     5701 cggaaaaaat aggggacaat atccttgtaa cacattcggc gggaggtttc ccgggatgga
     5761 tggccgctat acaaaatccg aatgtcaagg ctgtcgtttc atatgagccg ggtggctatg
     5821 tgtttcccga gggggaggtg cccgatccga tcgccggact taccggtggg gcggctggag
     5881 tagctattcc tatggaacag ttcttgcgac ttacccggat tccaatcgta atgtatttcg
     5941 gtgattatat tccggagact ccatcagaga atcttggtgg cgagaattgg cgtgtacgtc
     6001 tgcaaatggg acgtaaattc gtggaggcca taaataggca tgggggaaac gcgaccttag
     6061 ttgagttgcc caagatcggt atttatggta atacccattt cttgatgcag gatttgaata
     6121 atggccaact agcggatctg ctgggcgaat ggttggaaaa gaatgatctt ggcaaatagc
     6181 attgggaatg gttcttttaa gaacttgctg attttacatt ttgttatcgg attagataat
     6241 cggtaatata tcctcccaaa tatgtttctt caagtcaacg cagccattct tcttgaaggt
     6301 aatgccttct ttctccaata atccccgttg ttccgcccag ttgggagcta atctgccttg
     6361 gctgtttacc acccggtggc aaggcaggtt cagttctttc gggacgttga acattgcctg
     6421 ccctaccata cgggaacatt gtggccttcg ggcgagcttg gctagctgcc cgtaggtaac
     6481 cacacatcct tccggtatct ctctgacgat gttataaact tccgtataaa aatcagcctt
     6541 cattgattct ggtttttatt ttcgcccatg cgtgtgtttc gtatagggag gagttacgca
     6601 ttgtctgata catcgtcttg aaacgtgaca tcgggatcgt gagacttaat aagttgcttt
     6661 ccacatatgg tcggaccgag ggatcgaaga aaccaaggaa cgtgcggtga cctccttgtc
     6721 tattttcgtt gacagtgagc gtgatggtgg agctgcaacc ggaaccaaat ggtgtggaga
     6781 cggcatccgg attattgttg tcgaaaaagg tccaagtaat taaccctgac aagatgtccg
     6841 gagtcgcgag gaacaaaagc ccctctacct tttcaaacga ggttaatcga tcgatccttg
     6901 cgaaatggag gtatctgata atctcgcctt gcctgatagc gggaagggcc ttgaataaac
     6961 agccttgtgt ctgctttaat tctccaagca gagaatcgga ataccagaaa gcgatcggcg
     7021 attccgcctt tagagaaaat gcctcgtaat aattgttgat gaaagtttga atatccatat
     7081 gcgattgatt taggttgatt tattcttacc aatcgatttc cgggatgcct ttaccccgta
     7141 agaaatcatt agccttactg aaatgcttac aaccgaagaa accatattcg gcggagcggg
     7201 gagat
//
LOCUS       DBMDTB010000147         7153 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_2757_length_7153_cov_9.304736, whole genome shotgun sequence.
ACCESSION   DBMDTB010000147 DBMDTB010000000
VERSION     DBMDTB010000147.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 7153)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 7153)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7153
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2757_length_7153_cov_9.304736"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..2802)
                     /locus_tag="ACZPB4_15810"
     CDS             complement(<1..2802)
                     /locus_tag="ACZPB4_15810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099718.1"
                     /translation="MNKQWNKDGLTRKKLENDFRIHEPFQVLEKNLSNLLARAFSKSS
                     FLYHYQSLAILNEIKQTDTIGIEQSFILWQNENSPESNREITYLRNALYHKFSDWYQR
                     LNHRIFRDSMSDLFLDMEKYNQRLQLITLSNPKTVRRSLYLLLRILRNLQNKREIYIQ
                     EIAKSGETDPSLAVLIAFLKNYQYLVDQFNKRWEAYPLFYVNQILKESPQKAIIPSAW
                     FIAVKNNTARQAQLPKGTGIITQVPFPAQDIQFCYRTDEDYSVNDMKITSIHSLLLEK
                     DPKKYPASRLGFVTSIWQKQLNDRIGNVPSKKPNLDSELIFENQSSIQAGLMIESPML
                     LLREGHRDIHITFGLEEDSISYFKELIATTEQSSHETGRVLNDAFLLELSTEKGWAPI
                     YAYTLTFINENSFYLKFVLNEKFDPTTPCSEAHGCQTRNPALRILMNTDAWLFPYSWV
                     HRIFITSLKIKVHVSGMSSLKIYNPLGEVDASVHFPLFGLEAQKGSWFAFGNYEIAIK
                     PIQSMGITLQWADLPYSEGGFYDLYQAYKTPIDNTTFKVEWEKLTDQKWVKLPESTSC
                     LFNTKNKHTSPRGKLSEYSEIVYDKPFKNITVSTEEEQYQYMKAQQGFFRIRLTDPNG
                     GFGQTEYRMLFADIMIRNSHTRKQTPVPKPPYNPMIESIGIGYSAEEEYFFNGDTPRD
                     RCRIYHIHPLRQKELHEIDLRHPFPMVEVPTEDGIILFGIGNLIGNDQIRLFFEMAAL
                     KREIEKEYLPCVQWSFFNGKQWEFIKPGNLLSDTTGNLLNTGLVDILLPSPISEEMLD
                     INGDFWLSAKVSCHTQNCSSIRNVYLNPVKARLEIPEEMEALIGEELESFTGLVSFEK
                     SMPGLTDIYQIIPAKGGRSPETPEDMRLRITQEMSHRNRAVLPRNYEQITLAQFPEVE
                     KVLCLPGIDSKAQNRSPIVT"
     gene            complement(2799..3203)
                     /locus_tag="ACZPB4_15815"
     CDS             complement(2799..3203)
                     /locus_tag="ACZPB4_15815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPW/gp25 family protein"
                     /protein_id="HIR1099719.1"
                     /translation="MQNKNSFLGKGWAFPPEFSHNDNPTRMFNYEEDIRQSLIILLST
                     RTGERIHRPDYGTELYRYQFEQLDLTMETMIKSAIEKAVLLYEPRVSLDRIEINKASI
                     QDGILIIELYYTIRMNNVQQELTYPIYFDSNR"
     gene            complement(3216..4655)
                     /gene="vgrG"
                     /locus_tag="ACZPB4_15820"
     CDS             complement(3216..4655)
                     /gene="vgrG"
                     /locus_tag="ACZPB4_15820"
                     /inference="COORDINATES: protein motif:HMM:TIGR01646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system tip protein VgrG"
                     /protein_id="HIR1099720.1"
                     /translation="MSCNFGRKNNVYENSKDDTVIKKILGQYGLSAKVDSTGIEIPQL
                     VQYYCTDWDFVLTRAQNNGLVVITDGKQVKVCKPNVSASPVLTITYGDNLIAFDGSIS
                     ASEQYTDTKACAWDVSRQQIIKATASKPPLNAQGDIAAKDLSGLANEVMLYQTNAPIG
                     DASLHAWADAQALWSGLARFQGSITIYGNASIIPGCIIKLEGLSKHYRGNAFVQSVEH
                     TLQGGEWKTQVYMGFNPVVITEEPDVVAPAASGFLPGIRGLQIGIVKKIGDNKDFENF
                     ILVDIPLLQCEKTEIWARPVSPYASNGVGMLFLPEVDDEVVLQFINEDPCHPVIIGSL
                     YSRKRKTPVSLDPKNNLKTIVTKNQLKITLDDDKKIITIGTPGENTLILDDDKKQILL
                     SDANKNKVCMDKNGIMVESGKDLIFKARGNVKTEGMGIESKSKQDTKINGLNIEVSAQ
                     MGVKVKGSATAEISASGQTVVKGGVVMIN"
     gene            complement(4553..4972)
                     /locus_tag="ACZPB4_15825"
     CDS             complement(4553..4972)
                     /locus_tag="ACZPB4_15825"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099721.1"
                     /translation="MDNSFIIKLFLNSKDVTEQYSVINAKIYRACNKIDKATISISAD
                     IIDNSQFEIPDNKIFNPGTELKFQAGPTDKVNTLFEGCVTTHQLKINSEQQTLFILEC
                     RGFAYPATLDVKIMYMKIVKMIPLSRRFWDNTGFPPK"
     gene            complement(4978..5634)
                     /locus_tag="ACZPB4_15830"
     CDS             complement(4978..5634)
                     /locus_tag="ACZPB4_15830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CIS tube protein"
                     /protein_id="HIR1099722.1"
                     /translation="MNQKLIIEAYKSIEYKGGEKLGSITVQINPDSYKLSKSTSYKKD
                     ESIKEDKQLPEYKHTNPSTLSFDIHFDGTGIIPTGKKTVTERIKDLENIIFLPSAEID
                     PPSPCFLKVIWGSLIFKGRLTCLNWDYTLFSPNGNPLRAKGSLSLTEAISSRETQAKK
                     KNQKAEGKFVTFKQGDSLIGLCAKEYKNSGYAPMIASINNLISFRDIKPGTQLWFPKI
                     "
     gene            complement(5796..6299)
                     /locus_tag="ACZPB4_15835"
     CDS             complement(5796..6299)
                     /locus_tag="ACZPB4_15835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0098015 - virus tail [Evidence IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HIR1099723.1"
                     /translation="MLRFDHIVPPPVAFYFNVTFEGLIETSFQEVSGLQLEMETETIK
                     EGGENSFSYQVPTRRKHGNLVLKRSLMPLPHVLETYVVKVLENNGSAQIVPVNLTISL
                     LDAGHFPLNNWSVLNAYPVKWDISALNSQKNELVIETLEMAYTNLIRMSIRDTEDTKK
                     EQFKQWL"
     gene            complement(6299..6751)
                     /locus_tag="ACZPB4_15840"
     CDS             complement(6299..6751)
                     /locus_tag="ACZPB4_15840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0098015 - virus tail [Evidence IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HIR1099724.1"
                     /translation="MAGEAQDNVWPLPSFYFKVELGSLGEIAFKEVSGLDMEAQVIEY
                     RHGNSPVFSNIKMPGLKKTSNVSLKKGVFKADNKLFDWFNKIKMNTIQREDVTISLLD
                     EAGSPTMVWKLSNAWPTKVTGVSLKSDGNEAAIETLDLAHEGLTIENA"
     gene            complement(6788..>7153)
                     /locus_tag="ACZPB4_15845"
     CDS             complement(6788..>7153)
                     /locus_tag="ACZPB4_15845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath C-terminal domain-containing
                     protein"
                     /protein_id="HIR1099725.1"
                     /translation="WGARTMDGNSLDWRYINVRRTMIFLEESIKNAARAYVFEPNVVN
                     TWVNMRSMIDGFLRGVWKRGGLAGTSPEDAYSIHIGLGDTMTPEDILEGILRISVFVA
                     ITRPAEFIEITFQQQMQKS"
BASE COUNT         1835 a         1499 c         1466 g         2353 t
ORIGIN      
        1 tgttacgatc gggctcctgt tttgagcttt actgtctatt ccgggcaagc aaagtacttt
       61 ttcgacttcg gggaactgag ccaatgttat ttgctcgtaa ttcctaggca atacagcccg
      121 gttccgatgg gacatctctt gggtgatccg gagccgcata tcctctggcg tttccggcga
      181 acgtcctcct ttagcgggta tgatctggta aatatccgta agtcccggca tacttttctc
      241 gaaagaaacg agtcccgtga agctttcgag ttcctcaccg atcagggctt ccatttcttc
      301 ggggatttct aaccgggctt tcactgggtt tagatagaca tttcgtatgg atgaacaatt
      361 ttgcgtgtgg caagatactt ttgccgaaag ccagaaatct ccatttatgt caagcatttc
      421 ctcgctaata ggtgagggaa gcaggatgtc taccaaacct gtattcaaca gattcccggt
      481 tgtatcggaa agtaaattac ccggtttgat aaactcccat tgcttgccgt tgaagaaaga
      541 ccattgtacg caaggaagat attctttttc gatttcccgt ttcaaggcag ccatctcgaa
      601 gaataaacgg atctggtcgt taccgatcaa gttaccaata ccgaatagaa taatcccatc
      661 ttctgtgggt acttccacca ttgggaacgg atgacgtaga tcgatttcat gtaattcctt
      721 ttgcctcaat ggatggatat gatagatacg gcatctatct cttggggtat cgccattgaa
      781 aaagtattct tcctcggcgc tataaccgat acctatactt tcaatcatag ggttgtaagg
      841 aggtttgggc accggggtct gtttacgggt atggctgttt cttatcatga tatccgcaaa
      901 gagcatccgg tactccgtct gcccgaatcc gccgttcgga tctgtgagtc taatcctgaa
      961 gaagccttgc tgggctttca tgtattgata ttgctcttct tccgtggaga ccgtaatgtt
     1021 tttgaacggt ttgtcgtaaa cgatctcgct gtactccgag agctttcccc taggggaagt
     1081 atgcttgttt ttcgtattga agagacaaga tgtactttcc ggtaatttta cccatttctg
     1141 gtctgttagt ttttcccatt caactttgaa ggtggtatta tcgataggtg tcttatatgc
     1201 ttgatacaaa tcatagaaac ctccttccga ataaggtaga tccgcccatt gcaaagtaat
     1261 acccatggat tggataggct tgatcgctat ctcataatta ccgaatgcga accatgagcc
     1321 tttttgagct tctaacccga ataaagggaa atgtacgctt gcgtctactt ctcccagagg
     1381 attatagatt ttcaaggatg acatgccgga tacatgtacc tttatcttta agctagtaat
     1441 aaaaatacgg tgtacccaag agtaggggaa taaccaagca tccgtgttca tcaatatacg
     1501 gagcgctggg ttccgtgttt ggcaaccatg agcttcagag caaggtgttg tagggtcgaa
     1561 tttctcatta aggacgaatt tcagataaaa ggagttttcg ttgatgaatg tcaaggtgta
     1621 ggcgtatatc ggggcccaac ctttctctgt gcttaactcc aataggaaag cgtcgtttaa
     1681 tacacgcccg gtttcgtggg aagattgttc cgtagtagcg attaattctt tgaaatatga
     1741 tatggagtct tcttctaatc cgaatgtgat atgtatatcc cgatgtcctt cccgaagtaa
     1801 taacatggga gattcgatca tcagtccggc ttgtatagag gattggttct caaagattag
     1861 ctctgagtcc agattgggct tcttagaagg aacgtttccg atcctgtcat tcaactgttt
     1921 ttgccagatg gacgtaacga agcctaatcg gctcgctgga tattttttcg gatctttttc
     1981 caatagtaac gaatgtatac tcgttatttt catgtcattg accgaataat cttcgtccgt
     2041 acgataacaa aattggatat cttgcgcagg aaatggtacc tgtgttataa tacctgtacc
     2101 cttgggtaac tgggcttgcc gtgcggtatt attcttcacg gcgataaacc aagcggaagg
     2161 aataatcgct ttttggggag attccttcaa tatttggttg acataaaata acggataagc
     2221 ttcccagcgt ttattgaact gatctaccag atattgatag tttttcaaga aagcgattaa
     2281 aacagctaat gagggatcgg tctctccgct tttagcgatt tcttggatgt aaatctcccg
     2341 tttgttttgt aaattgcgga ggatacgtaa taataggtag agacttctac gaaccgtttt
     2401 aggattggat agggttatta gctgaagtct ctggttatat ttctccatat ccagaaataa
     2461 atcggacatg gaatctctaa agatccgatg attcaatctt tgataccaat cagagaactt
     2521 atggtataga gcgtttctta gataggtgat ttctctgtta ctttccggtg agttctcatt
     2581 ttgccacaaa atgaaactct gttcgatccc gattgtatct gtttgcttga tctcattgag
     2641 tatggctaag gattggtaat gatataaaaa ggatgatttc gaaaaggcac gagccaataa
     2701 attggagaga tttttctcga gtacttgaaa aggctcatgt atccggaaat cattctccaa
     2761 tttttttctt gtcaatccat ctttattcca ttgtttattc atcggttaga atcaaaatag
     2821 ataggatagg tcaattcttg ttggacatta ttcatacgta tcgtataata aagttcgata
     2881 atcagaatgc catcttgaat cgaagcctta ttaatttcta tgcgatcaag cgagactcta
     2941 ggctcgtata agagaacagc cttctcaata gcgcttttaa tcatggtctc catggtaaga
     3001 tctaattgtt caaactgata acgatatagt tccgtaccgt aatccggacg atgtattcgc
     3061 tcccctgtgc gagtggagag aaggatgatc aagctttgcc ggatgtcttc ttcataatta
     3121 aacatgcggg tgggattatc attatggctg aattctgggg ggaatgccca tcctttacct
     3181 aaaaaactat ttttattctg cataaatcat tcgatttaat taatcattac aacgcctcct
     3241 tttacaacgg tttggccgga tgcggatatt tcggcggtgg cagacccttt tactttaact
     3301 cccatttgtg cggaaacctc gatattcaag ccatttatct tggtatcttg cttagacttg
     3361 gattcgatac ccattccttc tgtcttgaca ttccctcttg ccttaaatat gagatctttg
     3421 ccggattcta ccataattcc gtttttatcc atacagacct tgttcttatt agcatcggat
     3481 aacagaattt gctttttgtc atcatccaat atgagcgtgt tctctccggg agtccctatt
     3541 gtgataatct ttttatcatc gtccaaagta attttcaact ggttttttgt aacaattgtc
     3601 tttaaattat tttttggatc taaagaaacc ggcgtttttc gtttgcgact gtacaaactt
     3661 ccgataatca cagggtggca ggggtcctca ttgatgaatt gcaggactac ctcatcatcg
     3721 acttccggta gaaataacat gccgacccca ttgcttgcgt acggactgac cggccgagcc
     3781 catatctccg tcttctcaca ttgtaacaag ggtatatcga ctaatataaa attctcgaaa
     3841 tctttattat ctccgatctt tttaacgatc cctatttgta atcctcgtat accgggcaaa
     3901 aaaccactag ctgcgggagc gactacatcg ggctcttcgg taatgactac cggattgaaa
     3961 cccatataga cttgtgtctt ccattcgcct ccttgtagtg tatgttctac tgattgaaca
     4021 aatgcgtttc ctctataatg tttgcttaat ccttctaatt tgataataca gcccggaata
     4081 atagacgcat tcccgtaaat tgtgatggag ccttgaaaac gtgccagacc gctccataaa
     4141 gcttgcgcat cggcccaagc atgtaaagaa gcgtcgccga tgggagcgtt agtttgataa
     4201 agcatcactt catttgccag accggataga tcctttgcgg cgatatcgcc ttgggcattg
     4261 agaggaggtt tgctggcggt ggctttgata atttgttgac ggctcacgtc ccaagcgcaa
     4321 gcttttgtat ctgtgtattg ctcggaagcg gatatagaac catcgaaagc gattaaatta
     4381 tctccatagg tgatggttaa gaccggggag gcggatacat tcggtttaca taccttgact
     4441 tgtttaccgt cagtgataac gactaatccg ttattttgtg ctcgtgtgag tacaaaatcc
     4501 caatctgtac aatagtattg taccagttgt ggaatttcta taccggtgct atctactttg
     4561 gcggaaagcc cgtattgtcc cagaatcttc ttgataacgg tatcatcttt actattttca
     4621 tatacattat ttttacgtcc aaagttgcag gatatgcgaa acccctacat tctaaaataa
     4681 atagagtttg ttgttcgcta ttgattttta actgatgggt tgtaacgcat ccctcaaata
     4741 aggtgttgac cttatctgtt ggacccgctt gaaacttaag ctccgtaccc ggattgaata
     4801 ttttgttgtc tggtatttca aattggctgt tgtcgataat atcagcgctg atggagatcg
     4861 ttgctttatc gatcttatta catgctctgt atatttttgc attgattacg gagtattgct
     4921 ccgtaacatc tttactattt aggaatagtt tgattataaa tgaattatcc atattcatta
     4981 tattttaggg aaccataatt gagttccggg ttttatatct ctaaagctga ttaggttatt
     5041 tatggaggca atcattggag cataaccaga atttttatat tcttttgcgc ataacccgat
     5101 tagactgtct ccttgtttaa aagtaacgaa tttaccctca gctttttgat ttttcttttt
     5161 tgcttgtgtc tctctactac taatcgcctc agttagtgac aaggagcctt tagctcgtaa
     5221 aggattgcca ttgggcgaga ataaggtgta atcccaattt aggcaggtta atctcccctt
     5281 gaaaatgaga ctcccccaaa ttactttaag gaagcaaggg ctgggtggat cgatctccgc
     5341 gctaggaaga aaaatgatat tctccaaatc cttgatcctt tctgtcacgg tttttttccc
     5401 cgtcgggata ataccggtac catcgaagtg tatatcaaat gagagagtgg aggggttggt
     5461 gtgtttatac tccggtagtt gcttatcctc ttttatgctt tcgtctttct tataggaggt
     5521 agatttgctt aacttatagc tatccggatt gatttggacg gtgatactac ccaatttctc
     5581 gccacctttg tattcaattg atttatatgc ctcgatgatc aacttttggt tcatgtttta
     5641 ccgctccttt ctacaagaaa aaaggtttga caaatctttc ttggcctcac gaattacctc
     5701 ctctttgatt tgttgtatca aatcacggga gagagggagg tcgggttcct ttttctgctg
     5761 tgtcactttt gcggacactt ggatttcttt tatagttata gccattgctt aaattgttct
     5821 tttttcgtat cttctgtatc tcttatcgac atacggatca aattagtata agccatctcc
     5881 aatgtttcaa tcaccagctc attcttttgg gaattcaatg cgctaatgtc ccattttaca
     5941 gggtaagcat tgagcacaga ccaattattt aggggaaaat gcccggcatc cagcaatgat
     6001 atagttaaat tgacgggaac gatctgggca cttccattat tttccaatac tttaaccaca
     6061 tatgtctcta gcacatgagg caaaggcatt aaagaacgtt tcaacacaag gttaccgtgc
     6121 tttcgtcggg taggcacctg atagctaaaa ctgttttctc ccccttcctt aatcgtttct
     6181 gtctccattt caagttgtag tcccgagacc tcttggaaag aggtctcgat caatccttcg
     6241 aaagtcacgt tgaaataaaa cgctaccgga ggagggacaa tatgatcaaa ccttagcatt
     6301 aagcgttttc tatggtcaat ccttcatgcg ctaaatctaa ggtttcgatg gcagcctcgt
     6361 ttccatcgga ttttaagctg acaccggtaa ccttagtcgg ccatgcgttc gataatttcc
     6421 aaaccatcgt agggcttcct gcttcatcca gtaagctgat tgttacatct tctcgctgta
     6481 ttgtgttcat ttttatcttg ttaaaccaat cgaataattt gttatccgct ttgaaaaccc
     6541 ctttctttag actgacattg ctcgtcttct tcagtcccgg catcttgata tttgagaaaa
     6601 ccgggctatt accatgtcgg tactcaatta cttgggcttc catatccaga ccagatacct
     6661 ctttaaaagc gatttccccg aggctaccta attctacctt aaaataaaaa ctgggtaacg
     6721 gccatacatt atcttgtgct tctcctgcca tattcgtatt ttttaatagg ttttaattct
     6781 taaattatca gcttttttgc atttgttgtt ggaatgtgat ctcgataaat tccgcaggtc
     6841 tggtaatagc cacgaatacg gatatcctga ggataccttc cagaatatcc tccggagtca
     6901 tcgtgtctcc caatccgata tgaatgctat atgcgtcttc gggggaagtt cctgctaatc
     6961 cacctcgttt ccatacgccc cgtaagaatc catctatcat actacgcata tttacccatg
     7021 tatttactac attcggttcg aatacatagg cacgggcggc gttcttgatc gattcctcta
     7081 ggaagatcat cgtacgcctt acgttaatat aacgccagtc taacgagtta ccatccatcg
     7141 tgcgggcacc cca
//
LOCUS       DBMDTB010000148         6857 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_2881_length_6857_cov_10.163410, whole genome shotgun sequence.
ACCESSION   DBMDTB010000148 DBMDTB010000000
VERSION     DBMDTB010000148.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 6857)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 6857)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6857
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2881_length_6857_cov_10.163410"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..273
                     /locus_tag="ACZPB4_15850"
     CDS             <1..273
                     /locus_tag="ACZPB4_15850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="eCIS core domain-containing protein"
                     /protein_id="HIR1099726.1"
                     /translation="SVRVHPDSSKAPEVGALAYTQGTDIHFAPGQFKPDTSAGQQLLG
                     HELTHVIQQAEGRVQPTTEVGGMAVNDDLSLEHEADVMGAKAASVL"
     gene            270..1577
                     /locus_tag="ACZPB4_15855"
     CDS             270..1577
                     /locus_tag="ACZPB4_15855"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HIR1099727.1"
                     /translation="MNEWIDWFQRVLDVSIRLYFRQECDLSSVYDIALPKAGPLWKAL
                     LPEQVDPTFDEWMVLMLALMPHLSPQVLDIFFVHNKNFDRPYTEFGGWKGLSHGGFLP
                     TGETAVFLLAGDRVERRLEVVRLFREEHWFHMYHVVGLEGAGNGEPFLSGQLRISEDF
                     LYRLSFEGEYKPDYNMGFPAKRISTALNWEDAVLPYYVREELEEINNWITGHRVILSD
                     WGLSRFLKAGYRTLFYGPPGTGKTLCATLIGKKNGMDVYRIDLSMIVSKYIGETEKNL
                     ANVFDQAENRNWILFFDEADALFGKRTSTNTSNDRHSNQEIAYLLQRIEDFPGTVVLA
                     TNLKSNIDEAFSRRFQSIIYFPMPDQDLREELWRRMLPSSWLPADADKMIRMAATYEL
                     SGGSISNVIRRCALRLLKQDTPRLDSDILSMAIRRELNKEGRW"
     gene            complement(1579..3702)
                     /locus_tag="ACZPB4_15860"
     CDS             complement(1579..3702)
                     /locus_tag="ACZPB4_15860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099728.1"
                     /translation="MSTRYRTTYHGILLGLLLHVIMAQAVNAQRSLSERLDYFRSLGE
                     RTELELEEIRTPIVSYQALMDSITQRILTEQCSYIVYPAELGNAFTFVINPDANQAIL
                     RLGYLQSPSSLLPDHVEQCAYTPWLFGNELLTASKNKANADPLFRFFDAMPGPVKVTQ
                     ALWYYFNKREPERILPPPTVENMYFFKGKTGDLDNMQSLLNSDKQGYIICPVWTEDVT
                     GVLDNPDENPSIRGSGTIEFFIKEAPLSIALNITPWEEDAIGYRETDFIPFVYDTTYT
                     QAVKNWLLSVRELRPSTIRTFFCYFDKRSKEEIATQKKKGNCSIPVFKVDGASSETER
                     LSERLSQYNQRAFPIVPYWLQSVYEQLPAGLIRKFSRMEYLGYVVDTESGQPSQVSDW
                     QQQECLVDMPVYSDTPVDLLVLFRNSKATNDFLRSKESQMALLNNLFTKDTGTINRNP
                     SLRKLNGLTLYFPDFDFKLENRRELVQFVKSTSFVIDSFCVMGNKIYRNYDLNVIFPI
                     KEKKHIGYLSILLKYQLVDRLCFVDYDEMGVPVTTCENRENKQEPVLKMVMYEEECEV
                     SLLDNLFNSLFYLLNPFPQGEQLTSCSDDLAQLANTEFSNPMLIYFVLGDIFLFLILL
                     ILINLYMTSSKFYMLAQHYKRYVLPLLLVFISEIVLVLYLITNIVSSRETFDIWTQMI
                     LLALPLFFFLLIIVPIGHREREPLP"
     gene            complement(3713..5431)
                     /locus_tag="ACZPB4_15865"
     CDS             complement(3713..5431)
                     /locus_tag="ACZPB4_15865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099729.1"
                     /translation="MDDLPNLQELKTEESIFDNLQKNALETIRELSGQLWTDHAPHDP
                     GITTLDILNYALSELDYQMSFPLEQYLTGSNNRFNPEDYGLFSPERVSGMAPVTPKDY
                     RDHFLDQLDNTDYLMNLSDLQIHPYRSNDQICHGWFDLFIELSSFISEDQHKQEEKKI
                     KEKIEELYHANRNLGEALHAIHFVRRKPLLLIGNIDIDGSISPEKTLIAIYTEAIQLF
                     APGSHYTGSALPIYKLFKGIKQIQGVLSIHSLEFQGFEEGEYAYTLALSSPEQIKIRL
                     YQNQQAVEINATKVLNRLHSRNNINHAIREQKKQAKSILMDSRHIHLNDYSVTNDFPI
                     CYKDSFTDSFKAYLSIFDHLFSEGHKEMNHLKDWMALNMGTPGSASMEQNKDLLLDTL
                     DKIYGENSNQPFLRYSHKEINRQRRVRFLRQLPELIRDRYLGCNLFDADSLSGLERYL
                     YSILGWEDAKEQIFILENILLHSPKATDHPVPSREFTLTAILSQTKRTRQRPDFQLRL
                     EEFLREKIPAHLRFTVHWLPPKELALFVKDYKAWRKAWADKDDKEIDRTGEILKNNLI
                     RINIEL"
     gene            complement(5434..6123)
                     /locus_tag="ACZPB4_15870"
     CDS             complement(5434..6123)
                     /locus_tag="ACZPB4_15870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099730.1"
                     /translation="MPNQKHFYELIDSMVNISDDGIDKNPDDGLRLAPSKENSPVISL
                     FTNIQDNIPEWKIYLGNNSQLHIIRQGQDEPILSLHPNGRIEMNQPGMDIRINGSLSA
                     TRFDGAIRGKFPADGEWHTLQIPTEGCRAYRIMAGCGKLKSGQYALVEATAIHCYGKH
                     RKIRTNQSWFGSFFNKIKFRWYGPGQKCKLQIRSGRDYGDNIFVCFQITDLWKDYRMD
                     ASDRRNTFNQE"
     gene            complement(6187..>6857)
                     /locus_tag="ACZPB4_15875"
     CDS             complement(6187..>6857)
                     /locus_tag="ACZPB4_15875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099731.1"
                     /translation="YEQITLAQFPEVEKVLCLPGIDSKAQNRSPIVTLVVMQKEKDKK
                     ILPLCEHRLLMRIEDYIGDKTSPFITVDAITPVYEEVTVCCNLRIKPGYPVGDILRQT
                     EARINNCIAPWRDKEEIPVFGLSFSSTDLYNSIRECEAIVDIDILSVAHVVYTAKDQQ
                     KSYYLNRYPEEARQNFNVSPSQPWCILVPSDRHLLYIDQKDELLEQLGLGYLGVGSNF
                     IINK"
BASE COUNT         1710 a         1416 c         1659 g         2072 t
ORIGIN      
        1 tcggtacgtg tacacccgga ttcatcgaaa gcgccggagg ttggggcttt ggcatatacg
       61 caaggtacgg atatccattt cgccccggga caattcaaac cggatacgtc tgccggacag
      121 cagctattgg gacatgagtt gacacacgtc atccagcaag cagagggacg tgtgcagcct
      181 actaccgagg taggtggaat ggccgttaac gatgatttat ccttggaaca cgaggcggat
      241 gtgatgggcg ctaaagctgc ttctgtctta tgaacgagtg gatcgattgg ttccagcggg
      301 tattggatgt ctctattcgt ttgtatttcc ggcaggagtg cgatttatct tccgtctatg
      361 atatcgcact cccgaaggca ggaccgcttt ggaaggcgtt gttgccggaa caggtcgatc
      421 ctactttcga tgagtggatg gtgttgatgt tggccttaat gcctcatctt tctccgcagg
      481 tgttggatat tttctttgtg cataataaga attttgaccg tccttatacg gaatttggcg
      541 gttggaaagg actatcgcac ggaggattct tgccaacggg cgagacggcc gttttcctgt
      601 tggcgggcga tcgtgtggaa cgccgtctgg aagtggttcg tctatttcgt gaggagcatt
      661 ggttccatat gtatcacgtc gttggcttgg aaggagccgg gaatggtgaa ccgttcttga
      721 gcggacaact gcgtatatcg gaggatttct tgtaccgttt atcttttgag ggagaatata
      781 agccggacta taatatgggt tttccggcca aacggattag tacggctttg aattgggaag
      841 atgccgtatt gccttattat gtgcgtgagg agttggaaga gataaataat tggattacgg
      901 gtcatcgagt catcctttcg gactggggat tgagtcgttt tttgaaggcc ggttaccgca
      961 ctttgtttta tggcccgccg ggaacgggta agacgctttg cgcgaccttg atcggcaaga
     1021 agaacgggat ggatgtatat cgtatcgatc tttccatgat tgtctccaaa tatatcggcg
     1081 agactgaaaa gaaccttgcg aatgtattcg accaagcgga aaaccggaat tggattctct
     1141 ttttcgatga ggcggatgcc ttattcggta aacgaacctc aacgaacact tctaatgatc
     1201 gccattcgaa tcaagagatc gcttatttgc tgcaacggat cgaggatttc ccgggaaccg
     1261 ttgttttggc cacaaactta aagagtaata ttgatgaagc tttctcccgt cgtttccagt
     1321 ctattatcta tttcccgatg ccggatcaag acttacgtga ggaattatgg cgtagaatgc
     1381 ttccctcttc ttggctacct gcggatgcgg acaaaatgat tcgtatggca gctacttatg
     1441 agttatcggg tggctccatc tcgaatgtga tccggcgttg tgcccttcgg ttgctaaagc
     1501 aagacactcc ccggctagat tccgatatct tatctatggc gatccgccgg gaattgaata
     1561 aagagggccg gtggtgattt aaggcaacgg ctctctttcc cggtgcccga tcggtacgat
     1621 gattaagaga aaaaagaaga gtgggagcgc caacagtatc atttgggtcc atatgtcgaa
     1681 agtttcccgc gaggatacga tattggtgat taggtataat accaatacga tctcggatat
     1741 gaataccagt aatagaggca agacatatcg cttataatgt tgtgccaaca tgtagaactt
     1801 actggatgtc atatacaggt tgattaggat taatagtatg agaaatagga atatatcacc
     1861 caatacgaaa taaataagca tcgggttgga gaattccgta tttgccagtt gcgccagatc
     1921 atcggagcaa ctggtgagtt gctcgccttg cggaaaagga tttagcaaat agaataaaga
     1981 gttgaaaaga ttatctagta aggatacctc gcattcttcc tcatacatga ccatcttgag
     2041 tactggttct tgcttattct ctcgattttc gcaagtagtt acaggaacgc ccatttcatc
     2101 gtaatcgaca aaacaaaggc ggtctaccaa ttggtatttc aatagaatgg atagataacc
     2161 gatatgcttt ttctccttga tagggaatat gacatttaaa tcgtagtttc tatatatttt
     2221 attacccatc acacaaaagg aatcaattac gaaactggtg gacttcacga attgtacaag
     2281 ttctctccgg ttctccagct taaaatcgaa atcagggaag taaagagtca agccgttgag
     2341 tttccggaga gacgggttcc ggttgatcgt gccggtatcc tttgtgaata agttatttaa
     2401 aagagccatc tgggattctt tcgatcttag gaaatcattc gtcgcttttg agtttcggaa
     2461 taggaccagc aaatcgacag gcgtatccga ataaacgggc atatctacca gacactcctg
     2521 ttgttgccag tcgcttactt gactaggttg cccgctttct gtatccacta cataccctag
     2581 atattccatc cggctgaatt tccggataag gcctgccggt aattgctcgt atacggattg
     2641 caaccaatac ggcacgatgg gaaaagctcg ttggttgtat tgacttaggc gttcggatag
     2701 gcgttcggtt tccgatgatg cgccatctac cttgaatacg ggaatactgc aatttccctt
     2761 tttcttttgt gtggcgatct cttctttgct acgtttatcg aaataacaga agaacgtacg
     2821 aatcgtggag ggacgcagct cacgcacgga tagcaaccag ttctttacgg cttgcgtgta
     2881 agtggtgtcg taaacgaatg ggatgaaatc ggtttcccgg tatccaatgg cgtcttcttc
     2941 ccaaggcgtg atgttgaggg cgatggaaag gggagcttct ttgatgaaaa actcaatcgt
     3001 tccgcttcct ctgatggagg gattctcgtc cggattatcc agaactcctg taacgtcttc
     3061 tgtccatacg gggcaaatga tatagccttg tttatcggag ttgagcaacg attgcatatt
     3121 atccagatct ccggttttgc ccttgaagaa atacatattc tcgacggtag ggggaggcaa
     3181 tatcctttcc ggttctcttt tattgaaata ataccacaaa gcttgcgtta ctttgactgg
     3241 gccgggcatt gcatcgaaga agcggaagag aggatctgcg ttggccttat tcttggatgc
     3301 ggttaataac tcgtttccga acaaccaagg tgtatatgca cattgttcca catgatctgg
     3361 taataaggaa ctcggggact gtaaataacc caaacgcaat atcgcttggt tcgcgtccgg
     3421 atttattacg aaagtgaaag cgttccccaa ttcagcggga tagacgatat aactgcattg
     3481 ctccgttaag atacgctggg tgatcgagtc cataagagct tgataggaga cgatcggggt
     3541 acgaatctct tccagttcca attcggtccg ctctcctaaa ctccggaaat aatccaatcg
     3601 ctccgagaga cttctttggg cgttaacggc ttgtgccatg attacatgaa gtaataagcc
     3661 caataaaatg ccgtggtagg tagttcgata tctggttgac ataagggtaa atttaaagtt
     3721 ctatatttat tcgtatcaga ttattcttta agatttctcc ggtgcggtca atctctttgt
     3781 cgtctttatc ggcccacgct tttcgccatg ccttatagtc tttgacaaat agggctagct
     3841 ctttcggagg aagccaatga accgtgaatc gtagatgtgc cggtatcttc tctcgcaaga
     3901 attcttcaag acgaagctga aaatccggcc gttgccgcgt acgttttgtt tgtgagagga
     3961 ttgccgttaa ggtaaattcc cgggagggga ctggatgatc agtcgccttc ggtgaatgca
     4021 ggagtatgtt ttccagaatg aaaatttgct ctttcgcatc ttcccatccg agtatggaat
     4081 agagatatct ttccaatccg gaaagggagt ctgcgtcgaa tagattacag cctagatacc
     4141 ggtcccggat aagttccggt agttgtcgca ggaaccggac tcttcgttga cggtttatct
     4201 ctttatggga gtagcggaga aaaggctggt tgctattttc gccgtagatt ttatccaacg
     4261 tatccaatag cagatctttg ttttgttcca tagaagcgga accgggggtt cccatattta
     4321 aggccatcca atcttttaga tggttcattt ctttatgtcc ctccgaaaag agatggtcga
     4381 atatagaaag atatgccttg aatgaatcgg taaacgagtc cttgtagcaa atcgggaaat
     4441 catttgtgac gctataatca ttcagatgga tatggcgact gtccatgagg atcgatttgg
     4501 cttgtttttt ctgttctcgt atcgcatggt tgatattatt ccgcgaatgc aaacgattca
     4561 atacttttgt ggcattaatc tctactgctt gttggttttg gtaaagtcgt atcttgattt
     4621 gctcagggga agataatgcc aatgtatagg cgtattcacc ctcttcaaaa ccttgaaatt
     4681 ccaaagagtg tatcgataga accccttgta tctgcttgat ccctttgaaa agcttgtata
     4741 tgggaagcgc actacctgta taatgacttc ccggtgcgaa taattgaatc gcctccgtat
     4801 aaatggcgat caaggttttt tccggagaga tgctaccgtc tatatcgata tttccaataa
     4861 gtaataaagg ttttcttctt acgaaatgga ttgcgtgtag ggcttctcct aaattccggt
     4921 tcgcgtgata tagttcctca atcttttcct tgattttctt ttcttcctgt ttgtgttgat
     4981 cttctgagat aaaggacgag agttctataa ataggtcgaa ccatccgtgg cagatctgat
     5041 cattggatct ataagggtgg atttgcaggt ccgataagtt cattaagtaa tcagtgttat
     5101 ctaattgatc taaaaaatgg tctcggtaat ctttgggtgt cacaggggcc atcccggaaa
     5161 cccgttcagg actgaacaag ccgtaatcct ccggattgaa acgattattc gatccggtga
     5221 gatattgttc taatgggaaa ctcatttggt aatccaattc gcttaaggcg taatttaaga
     5281 tgtccagagt cgtgattccc gggtcgtgcg gggcatggtc tgtccacaat tgtcccgaaa
     5341 gctcccggat tgtttccaag gcattctttt ggaggttatc gaaaatggat tcctccgttt
     5401 ttagttcttg caggttgggc agatcatcca tggctattct tgattaaagg tgtttctccg
     5461 gtcggaggca tccatccggt aatctttcca taaatcggtt atctggaaac aaacaaagat
     5521 gttgtctcca taatcccgtc cgctacgtat ttgcaacttg catttttgtc cggggccgta
     5581 ccaacggaat ttgatcttgt taaaaaagga accgaaccaa gattgattcg tacggatttt
     5641 tcgatgtttc ccgtaacaat ggatagccgt ggcttccacc aatgcgtatt gtccgctttt
     5701 taacttaccg catccagcca tgatgcggta ggcacgacat ccttccgttg gtatttgcag
     5761 ggtatgccat tcgccatctg cgggaaattt accccgtatc gcgccgtcga agcgggttgc
     5821 ggaaagactg ccgttgatac gtatatccat accgggttgg ttcatctcga tacgaccgtt
     5881 tggatgaagc gatagtatcg gttcatcttg cccttgacgt atgatatgga gttggctatt
     5941 gttacctagg tatattttcc actcaggaat attgtcttgt atgttcgtga ataagctgat
     6001 gacgggactg ttttccttgg aaggagctaa ccgtaagcca tcatccggat ttttatcgat
     6061 cccgtcgtcg gaaatattga ccatggaatc gattaattcg tagaaatgct tttggttggg
     6121 catacttccg cacttaaagt attcttttag tgtatttctg tttgtacgag gcatatccgg
     6181 tttgttttat ttgttaataa taaaattact tccaactcct aaatatccga gtccgagttg
     6241 ttccaatagt tcgtcttttt ggtcaatata tagcaaatgc ctatcagaag gaactaatat
     6301 gcaccaaggt tgggaagggc taacgttgaa attttgccta gcctcttccg ggtagcggtt
     6361 tagataatag ctcttttgtt ggtcttttgc cgtatatacg acatgcgcta cgcttaatat
     6421 atcaatgtcc acgatggctt cacactctcg tatggagtta taaagatcgg tcgatgagaa
     6481 cgaaagccca aataccggga tctcttcctt atctcgccaa ggtgcgatac aattattaat
     6541 gcgtgcctct gtctggcgga gtatatctcc tacgggatat ccgggcttta tccggaggtt
     6601 acagcaaacg gttacttcct cgtagaccgg agtgattgca tcaacggtaa tgaacggact
     6661 tgtcttgtca cctatataat cttcgattcg catgagtagc ctatgttcgc ataaaggcaa
     6721 gatcttttta tctttctcct tttgcatcac gaccaatgtt acgatcgggc tcctgttttg
     6781 agctttactg tctattccgg gcaagcaaag tactttttcg acttcgggga actgagccaa
     6841 tgttatttgc tcgtaat
//
LOCUS       DBMDTB010000149         6696 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_2944_length_6696_cov_12.617892, whole genome shotgun sequence.
ACCESSION   DBMDTB010000149 DBMDTB010000000
VERSION     DBMDTB010000149.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 6696)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 6696)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6696
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2944_length_6696_cov_12.617892"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..336
                     /locus_tag="ACZPB4_15880"
     CDS             <1..336
                     /locus_tag="ACZPB4_15880"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HIR1099732.1"
                     /translation="LSQLGPKQVVLTGVYFDEKELGAATFDMERNATEYVLTEKIPGY
                     YHGTGDVFASALLSGLLNNFNLERSAEIAVRFTTESILRTFKAQTDYRFGVNFEQSIP
                     DLLKELKLI"
     gene            386..1333
                     /locus_tag="ACZPB4_15885"
     CDS             386..1333
                     /locus_tag="ACZPB4_15885"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ketopantoate reductase family protein"
                     /protein_id="HIR1099733.1"
                     /translation="MAKLRIAFSGIGAVGGYYGGMVAARYQGTIKADIFFIARGENLK
                     AIRENGLQMQLGIRTIHTAPALATDNPAEIGPVDYLFCCTKSYDLEENIQQLKPVIGP
                     ETVIIPLLNGLDIEERIHNILPGQEVWKGCVYIGSRLTEPGVVEKFSLKERIFFGNKD
                     ANKDKQTELLKLLMYARLNAFNPADIDLRIWKKFFMISTAATATSFFNQPIDEVLAQH
                     IDLFIALGTELKSVAEAMGVRLPDDIVYTSIEMQKMMPAGSTTSMHSDFLAGKKTELE
                     TLTGYVIRQAEKLGVDVPTYRFMYNGLSFYPYPKKTEIS"
     gene            1336..1908
                     /locus_tag="ACZPB4_15890"
     CDS             1336..1908
                     /locus_tag="ACZPB4_15890"
                     /EC_number="3.2.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009292521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008725 - DNA-3-methyladenine glycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HIR1099734.1"
                     /translation="MQDIINGRCGWCGTDELYMRYHDQEWGKLVTDDKTLFEFLVLES
                     SQAGLSWITILRKREGYRKAFCDFDIERVAQMTDEDVERLMQFEGIVKNRQKIKSTIT
                     NARQFLSIQKEFGSFYNYTLSFFPNQKPIINTFQSLSEIPVSSPESEAMSKDMKKRGF
                     KFFGATICYAHLQASGFINDHLVDCVCRKR"
     gene            complement(1964..2941)
                     /locus_tag="ACZPB4_15895"
     CDS             complement(1964..2941)
                     /locus_tag="ACZPB4_15895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I phosphomannose isomerase catalytic
                     subunit"
                     /protein_id="HIR1099735.1"
                     /translation="MLYPFTFKPILKKVIWGGSDICPFKGITPVENGVGESWELSHVE
                     GNYSIVDNGELEGKSLDELIRSYGKELLGEKVMERFGTTFPLLIKFIDARDNLSIQVH
                     PDDELAKKRHNSFGKTEMWYVIKAEKGAGLYSGFSEQIDAEEYVKRVENNTIMDVLQR
                     YDVNEGDVFFLPAGRVHAIGAGCFIAEIQQTSNITYRIYDYNRKDVNGNGRELHTELA
                     KDAIDYTLYPDYRTHYKGHTNATVELADCKYFTTNLLDLDTIMVRNFSELDSFVVYIC
                     MAGKASIRDNKGNEIFVHQGQTVLIPADTEVITISPAPGAKFMETYIGQ"
     gene            complement(2964..4982)
                     /locus_tag="ACZPB4_15900"
     CDS             complement(2964..4982)
                     /locus_tag="ACZPB4_15900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0043169 - cation binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase C-terminal domain-containing
                     protein"
                     /protein_id="HIR1099736.1"
                     /translation="MESLNLIKNDPWLAPYEAAIEGRYQYVIDKEKSLTNNGKLTLSE
                     MASGYLYFGLHKTTKGWVFREWAPNATAIYLIGTFNGWQKDNKYKLKRKANGVWEIAL
                     TDAQMCHEDLFKLLVEWDGGSGERIPAWTRRVVQDEQSKIFSAQVWNPEKPYKFKNKR
                     FKPKKSPLLIYECHIGMSTNEEKVGTYNEFRQNILPRVAKDGYNAIQIMAIQEHPYYG
                     SFGYHVSSFFAASSRFGTPDELKQLIDEAHGMGLAVIMDIVHSHAVKNEVEGLGRFDG
                     SYDQYFLSGERREHPAWDSLCFNYGKNEVLHFLLSNCKFWLEEYKFDGFRFDGVTSML
                     YYSHGLGEAFCNYGDYFNGHQDGDAIAYLTLANKLIHEVNPGAITIAEEVSGMPGLAA
                     KIEDGGYGFDYRMAMNIPDYWIKTIKEKKDEDWHPSSIWWETTNRRADEKTISYAESH
                     DQALVGDKTIIFRLIDADMYWHMQKDDHNFMVDRGIALHKMIRLVTASTINGGYLNFM
                     GNEFGHPEWIDFPREGNGWSYKYARRQWDLVDNLDLKYHFLGDFDREMLELIGDVKNF
                     QDTPIQKVWDNDGDQILAYMRKDLVFVFNFSPTKSFTDYGFLVPKGEYEVVLNTDATR
                     FGGFGLADDTIRHFTQFDPLYKKEKKEWLKLYIPARSAVVLRKVKVKK"
     gene            5081..>6696
                     /locus_tag="ACZPB4_15905"
     CDS             5081..>6696
                     /locus_tag="ACZPB4_15905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HIR1099737.1"
                     /translation="MSKGTKSIAFYLMMILIFGSLMYFIAKEGESQQLENSIASIQNA
                     PSNLEEGFTIFTQLLVHNIESSIGILLLQIITILLTCRLFGWLFQKIGQPTVIGEIVA
                     GIVLGPSVLGNLFPEASAFLFPVESLVNINMLSQFGLILFMFAIGMELNISEVRKKLK
                     ETILISHTSTIVPFFFGMLTAYFVYDKYADKSTPFLSFALFIGIAMSITAFPVLARII
                     QEKGLTKTHLGTISLASAANGDITAWCLLAVVIAIAQAGSMLSAVYNILFSVLYIVFM
                     FLAVRPFLRMIGHIYHNKEVIDKGLVAFIFLLLITSAYLTEILGLHALFGAFIAGVVM
                     PGNVKFRKIMTEKVEDVSLALFLPLFFVSTGLRTEIGLLNKPELWWLCLIFIVVAIAG
                     KFGGAMFSARFVGESWKDSLYIGALMNTRGLMELVVLTIGYEMGILTPSVFVILVLMT
                     LVTTFMTTPLVSFIKFCYRAHDKLMEQKERMPLEGIFKVLLSFGRAGNGQIMLDVAYQ
                     MFAQGKNKLELTALHLTVGSDVNPLHTDNF"
BASE COUNT         1840 a         1578 c         1449 g         1829 t
ORIGIN      
        1 ctaagtcagc taggccctaa gcaagttgtc ttgaccggtg tctatttcga cgagaaagaa
       61 ctgggagccg ccactttcga tatggaacga aatgcgacag agtatgtttt aacagagaaa
      121 atacccggtt attatcatgg tacgggagat gttttcgcaa gtgctttact gtccggtttg
      181 ttaaataatt tcaacttgga gagatctgcg gaaatagccg ttcgcttcac gacagaaagt
      241 attcttcgaa cattcaaggc gcaaacggat tatcgctttg gcgtgaactt cgaacaatcc
      301 attccggatt tactaaaaga actgaaactg atataaatga gagccttttt tttctcatat
      361 ttgcaaataa aaggaatata atagtatggc taaattaaga atagcgtttt ctggtatcgg
      421 tgcggtgggt ggttattacg gaggtatggt cgccgcccgc tatcaaggaa caataaaagc
      481 agatatcttt tttatcgccc gtggagaaaa tctaaaggct atccgtgaaa acggtttaca
      541 aatgcaacta ggcatccgga caatccatac ggctccggca ctagccaccg ataatcccgc
      601 cgagataggg ccggtagact accttttctg ttgtacaaaa agttacgatc tagaagaaaa
      661 catccagcag ctaaagcctg ttatcggacc tgagaccgtt atcatcccct tgctaaacgg
      721 attggatatc gaagaacgaa tccataatat actacccgga caagaggtct ggaaaggatg
      781 tgtttatatc ggttcccgct tgacagagcc gggtgttgtc gagaaattct ccttgaagga
      841 acgtattttc ttcggcaaca aagatgcaaa caaagataag caaaccgagt tgcttaaatt
      901 acttatgtat gcccggttaa acgcttttaa tccagcggat atagacctac gcatctggaa
      961 gaaattcttc atgatctcta cggcggctac ggctacgagt ttcttcaacc agcccattga
     1021 tgaagtacta gcccaacata tcgacctgtt catcgctttg ggtacggaat taaaaagcgt
     1081 agcggaggct atgggagtcc gtttacccga tgacatcgtc tatacttcca tcgagatgca
     1141 aaagatgatg ccggccggct ccacgacttc catgcatagt gattttctcg ccgggaaaaa
     1201 aacagagttg gaaacattga caggatatgt aattcgtcaa gcggagaagc tcggcgttga
     1261 tgtccctact tatcgattta tgtataacgg attgtctttt tatccctatc cgaagaaaac
     1321 agaaatatca taattatgca agatataata aacgggcgtt gtggttggtg cggaactgac
     1381 gagttgtata tgagatacca tgatcaagag tgggggaagt tggtgaccga cgataaaaca
     1441 ctgttcgagt ttcttgtgct ggaaagttct caagccgggt taagttggat aactatcctt
     1501 aggaagcgtg agggatatcg caaggcattt tgtgattttg atatcgaaag agtggcgcaa
     1561 atgaccgatg aagatgttga acggttgatg cagtttgagg gaattgtgaa aaaccgtcag
     1621 aaaattaaat cgacaatcac aaacgcaagg cagtttctct ccatacagaa agagttcggt
     1681 agcttttata attacaccct atcattcttt cctaaccaaa aaccgattat caacaccttt
     1741 cagtcattga gtgagattcc ggtatcatct cccgaatccg aagccatgag caaagatatg
     1801 aagaaacgag gattcaaatt cttcggagcc acaatttgtt acgcccacct acaggcttcg
     1861 ggatttatca acgatcatct ggtggactgc gtttgccgaa aaagataata aaaaaggcgg
     1921 aaacagcatg ttcccgcctt cattattatt ttagtgagtg atcttattga ccgatataag
     1981 tctccatgaa cttagcgccc ggagccggag agatggttat tacctccgta tccgcaggga
     2041 tcaagacagt ttgaccttgg tgaacaaaga tctcgtttcc tttattatca cggatggaag
     2101 ccttgcctgc catacagatg taaacgacaa aagaatccag ttccgagaaa ttacgaacca
     2161 taatcgtatc cagatccaaa agattcgtgg tgaaatattt gcaatccgcc aactctaccg
     2221 tggcattcgt atgacctttg tagtgagtac ggtaatccgg atacaacgta taatcgatag
     2281 cgtctttcgc caattccgta tgcagctcac ggccattacc gttcacatct ttacggttgt
     2341 aatcgtaaat acgatacgtg atgttgctgg tctgctggat ctcagcaata aaacaacccg
     2401 ctccgatcgc atgcacacgt cccgccggca agaagaatac atcgccttca tttacgtcgt
     2461 aacgttgaag cacatccatg atcgtattgt tctccacacg tttcacatat tcctcagcgt
     2521 cgatttgctc agagaaaccg gaatacaggc cagcgccttt ctctgccttg atcacatacc
     2581 acatctccgt cttaccgaaa gagttgtggc gttttttcgc cagctcatcg tccgggtgaa
     2641 cttgaatgga taaattatca cgggcatcga taaacttgat aagcaagggg aaagtcgtcc
     2701 cgaatctctc catcaccttc tctcccagca attccttgcc ataagagcgg atcaactcat
     2761 ccaaagactt accttccaac tcgccattat cgacgattga ataatttccc tcaacatgag
     2821 aaagctccca gctctcgcct acaccattct caaccggagt aataccctta aacgggcaga
     2881 tatctgaacc gccccaaatc accttcttga ggatcggctt aaatgtaaat ggatataaca
     2941 taacgtgttt tgtgtataga gttttacttt ttgaccttca ctttccttaa tacgacggcg
     3001 ctacgtgccg ggatataaag tttcagccat tctttctttt ctttcttata taacggatca
     3061 aattgcgtga aatgccttat ggtatcatca gccaagccaa accccccgaa acgggtagcg
     3121 tcggtgttca atacgacctc atattctccc ttcggaacta agaaaccgta atccgtgaac
     3181 gatttcgtcg ggctaaagtt gaacacaaaa accaagtctt tacgcatata agccaatatc
     3241 tgatcgccat cattatccca aaccttctgg ataggggtat cttggaaatt cttcacatcc
     3301 ccgatcaatt ccaacatctc acggtcgaaa tcgcccaaga aatggtactt caaatccaag
     3361 ttgtccacca aatcccattg gcggcgagcg tatttataag accatccatt gccctccctc
     3421 gggaagtcga tccattccgg atgcccgaac tcatttccca tgaagttcag ataaccgcca
     3481 ttaatagtag aagccgtaac caaacggatc atcttatgca aggcgatacc tctatctacc
     3541 atgaaattat ggtcatcttt ttgcatatgc caatacatat cggcgtcgat caagcggaag
     3601 atgatcgtct tatcacccac caaggcttga tcgtggctct cggcataact gatcgtcttc
     3661 tcatcggcac gacggttcgt cgtctcccac cagatcgaag acggatgcca atcctcatcc
     3721 ttcttttcct tgatcgtctt gatccaatag tccgggatgt tcatggccat gcgataatca
     3781 aagccataac caccatcctc tatcttagcc gccaaacccg gcatgccact cacctcctcg
     3841 gcgatcgtta tagcgcccgg attcacctca tggatcaatt tattggccaa ggttagataa
     3901 gcgatagcgt cgccatcttg gtggccatta aaataatcgc cgtaattaca gaaagcctcg
     3961 cccaagccat ggctgtagta aagcatggag gtcacgccgt cgaaacggaa accatcgaac
     4021 ttatactcct ccagccagaa cttacaattc gacaataaga aatgaagcac ctcgttcttt
     4081 ccataattga agcacaggga atcccatgcc ggatgctcac ggcgttcgcc actcaggaaa
     4141 tattggtcat acgaaccgtc aaagcggcct aatccctcca cctcgttctt tacggcgtgg
     4201 ctatgtacga tgtccatgat cacggcgaga cccatcccgt gcgcctcatc gatcagttgt
     4261 ttcaactcgt ccggcgtacc gaaacgggaa gaggcggcga agaagctact tacgtgatag
     4321 ccgaacgatc cataataggg atgttcttgt atagccatga tctgaatggc gttataacca
     4381 tccttcgcta cacgaggtaa tatattttga cgaaattcat tatacgtccc caccttctcc
     4441 tcgttggtgc tcataccgat atggcactcg tagatcaaaa ggggagactt cttaggtttg
     4501 aatcgtttat tcttgaattt ataaggtttc tccgggttcc atacttgagc gctgaatatc
     4561 ttagattgct catcttgcac cacccggcga gtccatgcgg gaatacgttc tccgctaccg
     4621 ccgtcccact cgaccagcaa cttaaacaag tcctcatgac acatctgcgc atcggtcaaa
     4681 gcgatctccc atacgccatt cgccttacgt ttaagcttgt atttattatc tttctgccat
     4741 ccgttgaatg ttccaatcaa ataaatagcg gtagcattcg gcgcccattc acggaacacc
     4801 cagcctttcg tggttttgtg taacccaaaa taaagatatc cggaagccat ctcggataag
     4861 gttagtttac cattattcgt caggctcttt tctttatcaa tcacgtattg ataccggcct
     4921 tctatagccg cctcataagg ggccagccac gggtcatttt ttatcagatt tagagactcc
     4981 atgatttatt ataatttggt tctcggcaaa gataaaagaa aaaaacatac ccattgataa
     5041 tattaggata tttcttatat tcgcggtaaa ccgtacaaag atgagcaaag gaacaaaaag
     5101 tatagccttt tacctaatga tgatcctcat tttcggttcg ctgatgtact ttatcgccaa
     5161 agaaggagaa agtcagcaac tggaaaattc gattgcgtcc atccaaaacg cacctagtaa
     5221 tttagaagag ggatttacca tatttactca attattagta cataatatcg agtcttccat
     5281 aggaattctg cttttacaaa tcatcacgat attgcttacg tgccgtttgt tcggttggtt
     5341 attccagaag atcgggcaac ccaccgtcat cggcgagatc gttgccggaa tcgtgctagg
     5401 gccgtccgta ttaggcaatt tattcccgga ggcttccgcc ttccttttcc ctgtggaatc
     5461 gttggtgaat ataaatatgc tgagtcaatt cggacttata ctctttatgt tcgctatcgg
     5521 gatggaactt aatatctccg aggtaaggaa aaagctgaaa gagacgatct taatcagtca
     5581 taccagtacg atcgtcccct tctttttcgg tatgctgacc gcctatttcg tgtacgacaa
     5641 atatgcggat aagagtacgc ctttcctctc tttcgccttg tttataggta tcgccatgag
     5701 tattaccgcc tttcccgtat tggcacgtat tatccaagag aaaggactta ccaagacaca
     5761 tttgggtacc atctcgttgg caagcgcagc gaatggggat atcaccgcat ggtgcttgct
     5821 agcggttgtc atagcgatcg cacaagcggg ttcgatgcta agtgccgttt acaacatttt
     5881 attctcagtc ctttacatag tgtttatgtt tttggcggtg cggccattcc tgcggatgat
     5941 cggacatatt taccacaaca aggaggtaat cgacaagggg ctagtagctt tcatcttctt
     6001 gctattgatc acctcggctt atctgactga gatattggga ttgcatgcct tgttcggcgc
     6061 ttttatcgca ggggtggtga tgccgggaaa tgtcaaattc cgcaagatca tgaccgagaa
     6121 agtagaggat gtatcccttg ctctatttct tcccttattc ttcgtatcta ccggattacg
     6181 tacggaaata ggtcttctaa acaagcctga gttatggtgg ctatgcctta tcttcatagt
     6241 cgtggccatc gcgggaaagt ttgggggagc gatgttctcc gcccgattcg tgggtgagag
     6301 ctggaaggat agcctataca taggggcgct catgaatacc cgcgggttga tggagctggt
     6361 cgtattgacg atcgggtacg agatggggat attgacgcct tccgtattcg tgatcttagt
     6421 gctaatgacg ctggtcacca cctttatgac aacaccgttg gtctcattca tcaaattctg
     6481 ttaccgagcg catgacaagc tgatggagca aaaagagaga atgccattgg aggggatatt
     6541 caaggtactg ttgtccttcg gacgagccgg aaatggacag atcatgctgg acgtagccta
     6601 ccagatgttc gcccaaggca aaaacaaact ggagctgacg gcactgcatt tgacggttgg
     6661 ctcggatgta aacccgctac acacggataa tttcga
//
LOCUS       DBMDTB010000150         6344 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_3121_length_6344_cov_13.813231, whole genome shotgun sequence.
ACCESSION   DBMDTB010000150 DBMDTB010000000
VERSION     DBMDTB010000150.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 6344)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 6344)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6344
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_3121_length_6344_cov_13.813231"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            408..2243
                     /gene="ilvD"
                     /locus_tag="ACZPB4_15910"
     CDS             408..2243
                     /gene="ilvD"
                     /locus_tag="ACZPB4_15910"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005854456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004160 - dihydroxy-acid dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HIR1099738.1"
                     /translation="MKNPLRSSFSTEGRRMAGARALWRANGMKEEQFGKPIIAIVNSF
                     TQFVPGHTHLHEVGQLVKAEIEKQGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIA
                     DSVEYMVNAHKADAMVCISNCDKITPGMLMASMRLNIPTVFVSGGPMEAGELDGRHLD
                     LIDAMIESADTSVSDERIEQVERHACPGCGCCSGMFTANSMNCLNEAIGLALPGNGTI
                     VATHKNRIQLFRDAAKQIVENAYKYYRDGDDSVLPRNIATRQAFLNAMSLDIAMGGST
                     NTVLHLLAVAQEAGADFHMEDIDMLSRKTPCLCKVAPNTHTYHVQDVNRAGGILGIMN
                     ELMKAGLVDGSTRRADGLTLAEAVDKYAVTSPNVTEEAIRKYKSAPAHRFSIQMGSQE
                     SYYKELDTDRAEGCIRDVEHAYSKDGGLAVLRGNIALDGCVVKTAGVDESIWKFSGPA
                     KVFDSQDAACEGILGGKVISGDVVVITYEGPKGGPGMQEMLYPTSYIKSRHLGKECAL
                     ITDGRFSGGTSGLSIGHISPEAASGGAIGLVRDGDIIEINIPERSINVRLSDEELAER
                     RKAEEARGKKAFTPPTRQREVSKALRAYGKMVSSADKGGVRIVED"
     gene            2277..3980
                     /gene="ilvB"
                     /locus_tag="ACZPB4_15915"
     CDS             2277..3980
                     /gene="ilvB"
                     /locus_tag="ACZPB4_15915"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003984 - acetolactate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biosynthetic-type acetolactate synthase large
                     subunit"
                     /protein_id="HIR1099739.1"
                     /translation="MEKQKITGSEALLKALIAEGVDTIFGYPGGQAIPIYDSLYDYRD
                     QLRHVLVRHEQGATHAAQGYARVSGKVGVTLVTSGPGATNTITGIADALMDSTPMVVI
                     AGQVPSPLLGTDAFQEVDVIGITQPITKWAYQIRKPEEIAWAVSRAFYIASTGRPGPV
                     VLDLAKDAQVGLVEYEYKKVDYVRSYQPEPDINKDRIKAAADLINEAKKPFCLVGQGV
                     LLGGAEEELKAFLQKNDIPAGSTVLGLSALPTDFPLNKGMLGMHGNVGPNRKTNECDV
                     LIAIGMRFDDRVTGDLKTYAKQAKIIHLDIDNSEIGKNVPVDVKVLGNAKHTIPMITA
                     LLEERKRPEWNAEFDRDEKEEYDKVIEKELYPTEGQLKMGEVVRKVSEATGNDAVLVT
                     DVGQNQMMGVRYFKYKQTRSVVTSGGLGTMGFGLPAAMGAKFGAPDRTVCFFTGDGGM
                     QMTIQELGTIMQEKLNVKIIILNNNFLGMVRQWQELFFHERYSNTIMKNPDFVAIAKA
                     YGIAGRAVEKREELDDAIAEMLNHDGAYVLVANVETCGMVYPMVPAGGSVTNMIMGDE
                     K"
     gene            3996..4550
                     /gene="ilvN"
                     /locus_tag="ACZPB4_15920"
     CDS             3996..4550
                     /gene="ilvN"
                     /locus_tag="ACZPB4_15920"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005948 - acetolactate synthase complex
                     [Evidence IEA];
                     GO_function: GO:1990610 - acetolactate synthase regulator
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HIR1099740.1"
                     /translation="MTTKKLYTVIIFSENIVGLLNQITIIFTRRQLNIETLSVSPSAI
                     KGIHKFTITTFADEDMIDKVVKQIDKRVDILKAYYNTDEDLVYQEIALYKLSTELFIK
                     MGTVEGLIRKYNARILEMNETCVVLEKSGHYDETQALFNELSETIGVLQFIRSGRVAI
                     TKSKVERLSDMLADMERKLHEKQQ"
     gene            4557..5282
                     /locus_tag="ACZPB4_15925"
     CDS             4557..5282
                     /locus_tag="ACZPB4_15925"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016297 - fatty acyl-[ACP] hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HIR1099741.1"
                     /translation="MEKVGLFHFVAEPYLMDFRGRVTLPMIGNYLIHAASSHAGERGF
                     GFNDMSERHTAWVLSRLAIEMKEYPTAFDKINLYTWIDEVGRLFTSRCFELADENGKT
                     FGFARSIWAAIDVETRRPTLLDIEALGKYIDERPCPIEKPGKIMPAENKAEGIPYSIK
                     YSDLDINGHFNSVKYIEHLLDLFDIDQFKNREIGRLEIAYQSEGKQGMPLTLHKAESA
                     PDKQDMAICHEGKAICRAAVTWR"
     gene            5332..>6344
                     /gene="ilvC"
                     /locus_tag="ACZPB4_15930"
     CDS             5332..>6344
                     /gene="ilvC"
                     /locus_tag="ACZPB4_15930"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004455 - ketol-acid reductoisomerase
                     activity [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HIR1099742.1"
                     /translation="MAQMNFGGVVENVMTREEFPLEKAREILKDETIAVIGYGVQGPG
                     QSLNLRDNGFNVIVGQRQGKTYEKAVEDGWVPGETLFGIEEACDKATIIMCLLSDAAV
                     MSVWPTMKPYLTAGKALYFSHGFAITWNDRTGVVPPADIDVIMVAPKGSGTSLRSMFL
                     EGRGLNSSFAIYQDATGKAMDRTLALGIGIGSGYLFETTFIREATSDLTGERGSLMGA
                     IQGLLLAQYEVLRENGHTPSEAFNETVEELTQSLMPLFAKNGMDWMYANCSTTAQRGA
                     LDWMGPFHDAIKPVVEKLYANVKCGNEAQISIDSNSKPDYREKLEAELKALRESEMWQ
                     TAVT"
BASE COUNT         1628 a         1335 c         1800 g         1581 t
ORIGIN      
        1 aaagcatggc ttctagccgc ccgccctaaa acattggcac cttccgattc ctaagtaata
       61 cactcttgct cctgttaaaa tgcaatccta aaatggtgtt tgcttgagaa ttgaaagaaa
      121 aatgaagaat tttcttttaa atcctttgcg catatcaatt attgttctac atttgcagcg
      181 tcaaacaaac aaagacaata agaaaagatg atgaacaacg tattgcatat tattctcgtg
      241 gtggtccttc tagtcattag taggtaagga gaaaggtgtg taagaagttg tgaagtcgta
      301 gagatatttc ttaagccttt ctccatatag ggaaaggctt ttttattata aataaatcaa
      361 ggtagaggcg tggataaagc gctctacgaa caaaaaatag gaaagagatg aagaatccgt
      421 taagaagctc atttagcacc gaaggtcgta ggatggccgg agcccgtgcg ctatggcgtg
      481 ccaacgggat gaaagaggaa cagttcggca agcctattat cgctatcgta aattcattta
      541 cccagttcgt gccggggcat acgcatttgc atgaggtcgg gcaattggtc aaggccgaga
      601 tcgagaaaca aggttgtttc gccgctgaat ttaatacgat cgctatcgac gacggtatcg
      661 ctatggggca cgatgggatg ctttactcgc ttccttcacg cgacattatc gcggacagcg
      721 tggaatatat ggtaaatgcc cataaggcgg acgctatggt ttgcatcagc aattgcgata
      781 agatcacgcc gggtatgctt atggcttcca tgcgattaaa tatcccgacg gtgttcgtgt
      841 ccggtggccc gatggaggca ggtgagctgg atggccgcca tcttgatttg atcgacgcga
      901 tgattgagtc tgccgataca tcggtaagcg atgagcgtat cgagcaggtg gaacgccatg
      961 cgtgtccggg ttgcggttgt tgttccggta tgtttaccgc taactctatg aactgcttga
     1021 acgaggcgat cggtctggcg cttccgggta acgggacgat cgtggctacc cataagaacc
     1081 gtatccaact tttccgtgac gcggctaagc aaatcgtaga gaacgcttac aaatactatc
     1141 gtgacgggga tgattccgtg ttacctcgca acatcgctac ccgtcaggct ttcttgaacg
     1201 ccatgtcgct ggatatcgcc atgggggggt ctaccaatac agtgcttcac ttattggccg
     1261 tggcacaaga agccggcgcc gattttcata tggaggatat cgatatgtta tcccgcaaga
     1321 ctccttgcct gtgtaaggta gccccgaata cgcacactta tcatgtacaa gacgtaaacc
     1381 gtgccggtgg aatcctcggt atcatgaacg agttgatgaa agccgggctt gtggatggca
     1441 gcacgagacg tgcggacggc ctgaccttgg ccgaggctgt tgataaatac gccgtcactt
     1501 ccccgaacgt aacggaggag gcgattcgta aatacaagag cgctcccgct catcggttca
     1561 gtatacagat gggctcccaa gaatcttatt ataaggaatt agatacggat cgtgccgaag
     1621 gttgtatccg tgacgtggag cacgcttatt ccaaggatgg cggcttggct gttttgagag
     1681 ggaatatcgc cttggacgga tgtgtcgtaa aaaccgccgg tgtggatgag agtatttgga
     1741 aattctccgg cccggcgaaa gtcttcgatt cacaggatgc cgcttgcgag ggcattttag
     1801 gaggcaaggt catttcaggc gatgtggtcg tcatcacgta tgagggtccg aaaggggggc
     1861 cgggaatgca agagatgtta tatcctacct cttatataaa gagccgtcac ttaggtaagg
     1921 agtgcgcctt gatcacggat ggtcgtttca gtggcggtac gtccggtctt tctatcgggc
     1981 atatctctcc cgaggccgct tccggtggcg ctatcggact ggtgagagac ggggatatca
     2041 tcgagatcaa tatcccggaa cgttccatca acgtgcggct gagtgacgag gagttggccg
     2101 agcgccgtaa agcggaagaa gcacgtggaa agaaagcctt tacgccgccg acgcgtcagc
     2161 gtgaggtctc gaaagcattg agagcgtacg ggaagatggt tagctccgcc gataagggag
     2221 gtgtaaggat tgttgaagat taaagccaat aatatacatt aaacacgtta tttcttatgg
     2281 agaaacaaaa gataaccggt tcggaagctt tgctgaaagc gttgattgct gaaggagtag
     2341 atactatctt cggttatccc ggcggacagg cgatacctat ttacgacagt ttatatgatt
     2401 atagggacca gttgaggcat gtattggtgc gccacgagca aggcgctacc catgcggctc
     2461 aaggatatgc ccgtgtatcc ggcaaggtag gagtgacgtt ggttacttcc ggcccgggcg
     2521 ctacgaatac catcacgggt atcgctgacg cgctgatgga tagtacgcca atggtcgtaa
     2581 tcgccggtca agtaccctcg ccgttgttgg gaaccgatgc ttttcaggaa gtcgacgtga
     2641 ttggcatcac gcaaccgatc acgaaatggg cttatcaaat ccgcaagccg gaggagatcg
     2701 catgggctgt ttctcgtgct ttttatatcg cttctacagg ccgtccgggt ccagttgtgc
     2761 tggatttagc gaaggacgcg caagtagggt tggtggaata tgaatataag aaggtcgatt
     2821 acgtacgtag ttatcaaccg gagccggata tcaataagga tcgtatcaag gccgccgccg
     2881 atttaatcaa tgaggcgaag aaacccttct gtctggtcgg gcagggagta ttgttaggcg
     2941 gtgcggaaga ggaattgaaa gcgtttctcc aaaagaatga tatacctgcc ggatctacgg
     3001 tattgggctt atctgcgttg ccaaccgatt tcccattgaa caagggaatg ctcggtatgc
     3061 atggaaacgt agggccgaac cggaaaacga atgagtgtga tgtattgatc gctatcggta
     3121 tgcgtttcga cgaccgtgtg actggcgatt taaagacata cgctaagcaa gccaagatta
     3181 tccatctgga tatcgacaac tcggaaatcg gtaagaacgt ccccgtagat gtaaaggtgc
     3241 tgggtaatgc caagcacacg ataccgatga tcacggcgtt gttggaagaa cgtaaacgtc
     3301 cggaatggaa tgccgagttc gatcgggacg agaaagagga atacgataag gtaatcgaga
     3361 aggaattgta tccgaccgag ggccaactga aaatgggcga ggtagtccgt aaggtttccg
     3421 aggcgaccgg taacgacgct gtattggtga ccgacgttgg gcagaaccag atgatgggcg
     3481 tccgctattt caaatataaa caaacccgta gcgtggtgac ttccggtggt ttaggtacga
     3541 tgggatttgg tctgccggcc gctatgggcg ctaagttcgg ggctccggac cgtacggtct
     3601 gcttctttac cggtgatggg ggtatgcaga tgacgattca ggaattgggc actatcatgc
     3661 aggagaaact gaacgtgaag attatcattc ttaataataa cttcttaggg atggtacgtc
     3721 agtggcaaga attgttcttc cacgagcgtt attcaaacac catcatgaag aatccggatt
     3781 tcgtggcgat cgctaaagcc tatggtatcg ccggtcgtgc cgttgaaaag cgggaggaat
     3841 tggacgacgc tatcgctgag atgctaaacc acgacggcgc ttacgtgttg gtcgctaacg
     3901 tggagacttg cggaatggta tatccgatgg ttcctgccgg gggaagcgtg acaaacatga
     3961 ttatgggaga cgagaaataa ggaggagatg aagctatgac aacaaagaaa ttatataccg
     4021 ttattatctt ttcagagaat atcgtaggtc ttttgaacca gataacgatt atctttacac
     4081 gccgacagct gaacatcgag actctgtccg tctctccgtc cgctatcaag ggcatccata
     4141 agtttacgat cacgacattc gccgatgagg atatgatcga taaggtggtg aaacagatcg
     4201 ataaacgtgt ggatatcttg aaggcttatt ataatacgga tgaggatttg gtttatcaag
     4261 agatcgctct ttataagcta agtaccgagc ttttcatcaa gatgggaacc gtggagggat
     4321 tgatccgtaa atacaacgct cgtatcttgg agatgaacga gacctgcgtg gtgttggaga
     4381 agagtggcca ctatgacgag acacaagcct tgttcaatga gttgagcgag acgatcggtg
     4441 tcctgcaatt catccgctcc ggacgtgtgg ctatcacgaa gagcaaggtg gagcgcttga
     4501 gcgatatgtt ggccgatatg gagcgaaagt tacatgaaaa gcaacaataa taagatatgg
     4561 agaaagtagg attatttcat ttcgtggcgg agccgtattt gatggatttt aggggacgtg
     4621 taacgctccc tatgattggt aactatttga ttcacgccgc ttccagccat gccggagagc
     4681 gtgggttcgg tttcaatgat atgtcggagc gtcatacggc ttgggtgttg tcccgtctgg
     4741 ctatcgagat gaaggaatat cctaccgcct tcgataagat taatctatac acttggatcg
     4801 atgaggtcgg acgcctcttc accagtcgtt gttttgagct ggcggatgag aatgggaaaa
     4861 cctttggatt cgcccgttct atctgggcgg ctatcgatgt ggagacccgc cgtcctacct
     4921 tattggatat agaggcattg ggcaaatata tcgacgagcg tccgtgcccg atcgagaagc
     4981 cgggcaagat catgccggcg gagaataagg cggagggaat cccgtattcg atcaaataca
     5041 gcgacttgga tatcaacggt cacttcaata gcgtgaagta tatcgagcat ctgctggatt
     5101 tgttcgatat cgaccagttc aagaaccgtg agatcggccg tctggagatc gcctaccaat
     5161 ccgagggtaa acaaggtatg ccgcttacgc ttcataaggc ggagtccgct cccgataagc
     5221 aagacatggc tatttgccat gagggaaagg cgatctgtcg tgcggcggtt acttggagat
     5281 aataaaagag atacataaat aggtttttaa acattaatag ttaaaaagaa aatggcacaa
     5341 atgaattttg gcggtgttgt agagaatgta atgacccgcg aggaatttcc gttggaaaag
     5401 gcaagagaga tattaaaaga tgagacaatc gctgttatcg gctatggcgt acagggaccg
     5461 ggacagtcat tgaaccttcg tgacaatggt ttcaacgtaa tcgttggcca gcgccaaggt
     5521 aagacttacg agaaagcggt tgaggacgga tgggttccgg gtgagactct gttcggtatc
     5581 gaggaggctt gcgacaaggc cacgatcatc atgtgcttgt tgtccgacgc tgccgtaatg
     5641 tctgtatggc ctacgatgaa gccttatttg acagctggca aggccctgta tttctctcat
     5701 ggtttcgcga tcacttggaa cgatcgtacg ggcgttgttc ctcccgcgga tattgacgtg
     5761 atcatggtcg ctccgaaggg gtctggtacg tctttgcgtt ccatgttcct tgagggtcgt
     5821 ggcttgaact cttctttcgc tatctatcaa gacgctactg gcaaggcgat ggatcgtacg
     5881 ttggcgttgg gtatcggtat cggttccggc tacttgttcg agacgacttt catccgtgag
     5941 gctacttccg atttgactgg tgagcgtggt tctttgatgg gcgctatcca aggtttgttg
     6001 ttggcccagt atgaggtatt gcgcgagaat ggacacactc cttctgaggc tttcaacgag
     6061 acggtcgagg agttgactca atccttgatg cctttattcg ccaagaatgg tatggactgg
     6121 atgtacgcga actgctctac taccgcccag cgtggcgctt tggactggat gggtccgttc
     6181 cacgacgcaa tcaagccggt tgtcgagaaa ttgtacgcga acgtaaaatg cggtaacgag
     6241 gctcagatct ctatcgactc aaactctaag ccggattatc gtgagaaatt ggaggctgaa
     6301 ttgaaggcat tgcgcgagag cgagatgtgg cagacagctg ttac
//
LOCUS       DBMDTB010000151         6221 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_3209_length_6221_cov_10.655719, whole genome shotgun sequence.
ACCESSION   DBMDTB010000151 DBMDTB010000000
VERSION     DBMDTB010000151.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 6221)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 6221)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6221
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_3209_length_6221_cov_10.655719"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..2456
                     /locus_tag="ACZPB4_15935"
     CDS             <1..2456
                     /locus_tag="ACZPB4_15935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011965928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="glycoside hydrolase family 2 TIM barrel-domain
                     containing protein"
                     /protein_id="HIR1099743.1"
                     /translation="TSEANDIWVSPASPQTASFEYDLKNVAPWSAEHPNLYKLLMTIK
                     EEGKVIEVVPFNVGFRRFEMKQIDQVAEDGKPYTVLLFNGQPVKFKGVNIHEHNPETG
                     HYVTEELMRKDFELMKQNNINAVRLCHYPQDRKFYELCDEYGLYVYDEANIESHGMYY
                     SLKKGGTLGNNPEWLIPHMDRTMNMYERNKNYPSVTFWSLGNEAGNGYNFYQTYLYLK
                     DKEINSMNRPVNYERALWEWNTDMYVPQYPSAEWLEEIGRKGSDRPVAPSEYSHAMGN
                     SSGNLWDQWKAIYKYPNLQGGFIWDWVDQGILEKDKNGREYYTYGGDYGVNTPSDGNF
                     LCNGIVNPDRTPHPAMAEVKYAHQNIGFEAIDLANGLFRVTNRFYFTNLKKYMVHYSV
                     TANNKVVRSGKVSLDIEPQASKEFTVPVGNLKPQAGTEYFVNFNVTTVEKEPLIPIGH
                     EIACDQFRLPIESPKKAFKISGPKLTVSTNGDNLSASSSKVNFMFNKKTGIVTSYKVD
                     GTEYFSEGFGIQPNFWRAPTDNDYGNGMPKRLQVWKESSKNFNVTDATVTMDGNNAVV
                     NVNYLLPAGNLYIVNYTIYPSGAVNVAARFTSTDMDAAQTEVSESTRTATFTPGRDAA
                     RKEASKLNVPRIGVRFRLPASMNQVEYFGRGPAENYLDRNAGSMVGLYKSTAEELYFP
                     YVRPQENGHHTDTRWVSLSTGKKGLLIQADNTIGFNALRNSIEDFDDEEATGLPRQWS
                     NFTPEQVANHDEAAAKNVLRRQHHINDITPRDFVEVCVDLKQQGVAGYDSWGSRPEPA
                     YTLPANREYNWGFTLIPLK"
     gene            complement(2560..3543)
                     /locus_tag="ACZPB4_15940"
     CDS             complement(2560..3543)
                     /locus_tag="ACZPB4_15940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016209 - antioxidant activity [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin domain-containing protein"
                     /protein_id="HIR1099744.1"
                     /translation="MKQFCMMALAGLLVVGCQEVPKGYVINGEVENMPDGKIYLKSFR
                     NKMFFDVDTAEVKDGKFTFKGEVDQPLLFGLATENMNYPVQLFLENTDMNVKIGNDGE
                     TITVQNSPVNDVFQENTEKVFEEGYDIDSLISKYPDSPAAAFYLYRYFTYQLSLDDLK
                     ATRAKISPALANSPYVKDLDGIIKQLEHVQIGQVAPEFSLPDTVGVSVSLSDFRGKYV
                     LLDFWASWCPPCRKENPNVVNAFQQYKDKNFTIVGISLDKDKAKWQKAIADDHLTWAH
                     VSDLKYWDSEIPALYGVRGIPANVLLDPNGVIIAKNITGEDLQNTLKEVIK"
     gene            complement(3564..4334)
                     /locus_tag="ACZPB4_15945"
     CDS             complement(3564..4334)
                     /locus_tag="ACZPB4_15945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865877.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HIR1099745.1"
                     /translation="MIFYFTGTGNSRWVAEALGTAFDEPLVSIADALNEGKNAYPLGE
                     REKVFFVFPVHSWGPAVLVPRFISRLILSGYKGQEVYFVCTCGDDCGYTDRIMRSILA
                     RRGIAVTGGFSVQMPNNYVLMPGFDVDSKEVETEKLKKAPERVDEIVEAIRQKKNLSL
                     YCAGSAPLLKSYMVYPLFAHFAIGSNRFYATDTCISCGICAKVCPTGTISLSGDGKPE
                     WADTCVQCVACIHRCPVRAIEYGTISLKKGRYHHPKFK"
     gene            4422..4604
                     /locus_tag="ACZPB4_15950"
     CDS             4422..4604
                     /locus_tag="ACZPB4_15950"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099746.1"
                     /translation="MTTMELNLRKEYLYDLIKGMDEERLSKVETYIKRLCSPTSKKAT
                     NYPWTPSVEELESMIA"
     gene            complement(4908..6182)
                     /locus_tag="ACZPB4_15955"
     CDS             complement(4908..6182)
                     /locus_tag="ACZPB4_15955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HIR1099747.1"
                     /translation="MFRLEDMKKYIILSLLCGCLSANAQTMVPLTYRQYMERVAEGNL
                     EYASEKLNVPAAKAEVTAAKVFNDPNLSVSYFNNENNSLQMGEGVEVELSKTFSFGKR
                     GANISLARSESELTEALLADYFRNLRADATIAYMEALKQHELYKVKENAYENIRTLAE
                     SDSIRFSLGQIREVDATQSRVEAGVLRNELLQAGAELKNAFSNLNFLTGTFSTDTLFH
                     PEAELRTEPRDFILADLITAASEGRTDLVAALKNKEVAARALKVARRERNTDVDLSIA
                     VSRNARVYNEEAPAPPFTGVTAGIAVPLKFSNFNKGTVRAARYREQQAEAQYKQALLQ
                     VQTEVMQAYRNYQSFAEQVNHYQDGLLRQAREVMDGKIYSYNRGEVSLLEVLDAQRTY
                     DEVQAQYIETLFNYSSALVELERSAGIWDIEI"
BASE COUNT         1848 a         1522 c         1268 g         1583 t
ORIGIN      
        1 tgacctccga ggctaatgat atatgggtaa gtcctgcaag tcctcaaaca gcatctttcg
       61 agtatgattt aaagaacgta gccccttgga gtgccgagca tccgaatcta tacaaattat
      121 tgatgacgat aaaagaagag ggtaaggtaa tcgaggtagt tccattcaac gttggtttcc
      181 gccggttcga gatgaagcaa attgaccaag tagcggaaga cggaaaacct tatacggtct
      241 tattgttcaa tgggcaaccg gttaagttca agggtgtcaa tatccatgag cataacccgg
      301 aaaccggaca ttacgtaacc gaggaactca tgcgtaagga tttcgagctg atgaagcaaa
      361 acaatatcaa cgctgtccgc ctatgccact atccgcaaga ccgtaaattc tatgaactct
      421 gcgacgaata cggattgtat gtttacgatg aggcgaatat cgagtctcac ggtatgtatt
      481 acagcctgaa aaaaggcggc actttgggta ataatccgga atggctgatc ccgcatatgg
      541 accgtacgat gaatatgtac gaacgaaaca agaattatcc gagcgttact ttctggtcac
      601 tcggaaacga ggctggaaac ggatacaact tctatcaaac ttatttatat ctgaaagaca
      661 aggaaataaa tagcatgaat cgtccggtga actatgaacg tgccctttgg gaatggaata
      721 cggatatgta cgtacctcaa tacccgagcg ctgaatggct agaggaaatc gggcgtaagg
      781 gtagtgatcg tccggtagct ccttcggagt attcacatgc gatgggaaac tcttccggca
      841 acttatggga tcaatggaaa gctatctata aatacccgaa cctgcaaggc ggattcatct
      901 gggactgggt ggaccaaggt atcttggaaa aagataagaa tggacgtgaa tattatacct
      961 atggtggtga ctatggagta aacaccccta gtgacggaaa cttcctttgc aacggtatag
     1021 taaacccgga tcgtaccccg catcccgcta tggcagaggt taaatacgcc catcaaaata
     1081 tcgggtttga ggcgatcgat ttagcgaacg gtttattccg cgtcacgaac cgtttttatt
     1141 tcacgaacct aaagaaatat atggtccact atagcgtaac agccaataat aaagttgtac
     1201 gctccggtaa agtctctttg gacatagaac cccaagcttc taaggaattt acggttcccg
     1261 taggcaactt aaagccacaa gccggtacgg aatatttcgt aaacttcaac gtaacgaccg
     1321 tagaaaaaga gccgttaatc cctatcggac acgaaatcgc ttgcgatcaa ttccgcttac
     1381 cgatcgaaag ccccaagaag gcgtttaaga tcagcggccc taaattaacg gtttcaacca
     1441 atggagataa cttatcggca tcctcctcaa aggtaaactt catgtttaac aagaagacag
     1501 gaatcgttac ttcttataaa gtggatggta cggaatattt cagcgagggt tttggtatcc
     1561 aaccgaactt ctggcgtgcg ccgaccgata acgattacgg aaatggtatg ccaaaacgct
     1621 tacaagtatg gaaggaaagc agcaagaact tcaacgtaac agacgctacc gtcactatgg
     1681 atggcaataa cgccgtggtt aacgtgaact atttattgcc ggcaggaaat ctatacattg
     1741 ttaattatac gatctatcca agcggagctg taaatgtggc cgcccgtttc acatccacgg
     1801 atatggatgc cgcccaaacc gaggtatcgg aatctactcg cacggcaact ttcactccgg
     1861 gacgtgacgc cgcccgtaaa gaggcttcca aattgaatgt tccccgtatc ggtgttcgct
     1921 tccgcttacc ggcaagcatg aatcaagtgg aatatttcgg acgaggacct gctgagaact
     1981 acttggatag aaacgccggt agtatggtcg gcttatataa atctacagcc gaggaattat
     2041 atttcccata tgtacgcccg caggaaaacg gtcatcatac cgacactcgt tgggtatcac
     2101 ttagtaccgg caagaaaggc ttgttgatcc aagcggataa tacgattgga tttaacgctt
     2161 tgcgtaattc catagaggat ttcgatgacg aggaagcaac tgggctaccc cgtcaatgga
     2221 gtaatttcac accagagcaa gtagcgaacc atgatgaagc cgcagcaaag aacgtattac
     2281 gtcgccagca tcatatcaac gatatcacac ctcgcgactt cgttgaggtt tgcgtcgact
     2341 tgaaacaaca aggtgtagca ggttatgata gctggggttc acgtccggaa ccagcttata
     2401 cattacccgc aaaccgggaa tacaactggg gctttaccct tattccgctt aaataaagaa
     2461 aagtcataac cttatccata acaaagggag tgtattaggc ttaatccaaa tacactccct
     2521 ttgtttatac tactgcaacg gctttgcagt aacgtatcct tatttaatta cttccttcaa
     2581 ggtattctgt aagtcttctc cagtgatatt cttggcgatg atcaccccat tcggatccaa
     2641 taacacattt gccggaatac cccgtacccc ataaagagca gggatctcag aatcccaata
     2701 tttcaagtcg gaaacgtgag cccaagtcag atgatcgtca gcgatcgctt tctgccattt
     2761 agccttatcc ttgtccaagg atatacctac gatcgtaaag ttcttatcct tatattgctg
     2821 gaaggcattt accacgttag ggttttcctt gcgacacggg ggacaccaag aggcccaaaa
     2881 atccaataac acatattttc ccctaaagtc cgacaaagac acagaaactc ctacagtatc
     2941 cggcaaggag aactccggag cgacttgtcc gatctgtacg tgttctaatt gcttgataat
     3001 accgtccaag tccttcacat aaggactatt cgccaatgcc ggggaaatct tcgcacgagt
     3061 cgccttcaaa tcatccaaag ataattggta ggtaaaataa cgatatagat agaacgccgc
     3121 cgccggagaa tctggatatt tcgaaatcaa actgtcaata tcataccctt cctcaaatac
     3181 cttctccgta ttttcttgaa agacatcatt caccggtgaa ttctgtacgg taatagtctc
     3241 cccgtcattc ccgatcttga cattcatatc cgtattctcc aagaagagct gaaccggata
     3301 gttcatattc tcggttgcca aaccaaaaag taaaggctga tctacctcac ccttaaaggt
     3361 gaatttcccg tcttttacct ctgctgtatc cacgtcaaag aacattttat tacggaatga
     3421 cttcaagtaa atcttgccgt cgggcatatt ctctacctca ccattgataa catatccttt
     3481 tggaacttct tggcaaccaa ccaccaaaag gccggcaagc gccatcatac aaaattgctt
     3541 catttctcta ttctatttat tgattactta aacttagggt gatgataacg tccctttttc
     3601 aacgagatcg tcccatattc tatcgcacgc accggacaac gatgaataca ggcaacgcac
     3661 tgaacgcaag tatcagccca ttccggtttt ccgtcacccg acagggaaat cgtaccggtc
     3721 ggacagacct tcgcacagat accgcaagag atacaggtat ccgtagcata aaatcggttg
     3781 ctgcctatcg cgaagtgagc aaataacgga tagaccatat agctcttcaa aagaggggca
     3841 cttcccgcac aatacaaaga aagatttttc ttctgccgga tcgcctctac gatctcgtct
     3901 acacgttccg gtgctttttt cagtttttca gtctctacct ccttactatc cacgtcgaag
     3961 ccgggcatca agacataatt gttcggcatt tgtacagaga atcctccggt tacggcaatt
     4021 ccccgcctcg ccaagatgct ccgcatgatc cgatccgtat atccacaatc atcaccacaa
     4081 gtacagacga aataaacctc ttgcccctta tatccggaca ggatcaaccg ggaaataaag
     4141 cggggcacca atacagccgg cccccaagaa tggacaggga acacaaaaaa cactttctcc
     4201 ctctccccca atggataagc attcttaccc tcattcaacg catcggcaat ggaaaccaac
     4261 ggctcatcga aagccgtccc taacgcttcc gcaacccaac gggagtttcc tgtccctgta
     4321 aagtagaata tcatgcgctc attttttaga tgcaaaaata cataatatcc aaacatatac
     4381 gctatcttta tctagtttaa gaaacctaaa aaacaaatct tatgacaacg atggaattaa
     4441 atttacggaa agaatatctc tatgacttga taaaaggcat ggatgaggaa agattatcga
     4501 aagtggagac ctatataaaa cgtttgtgct ctcctacttc caaaaaggca acgaactacc
     4561 cttggacgcc atcggtagaa gaattagaat ctatgatagc ctaatctgaa gaaaactatg
     4621 agaagggact ttatatagag gaagaagaga tgaataagtt ttttgaatcg atgagatgaa
     4681 acaagccatt acaaaatatt gtattgtata gaaaatgatg atttcatcca cattgtagtc
     4741 gttttcgatt gcaggcaacc ccccaataaa taaatatctt tttttacata aaaaaacagc
     4801 tatatcaaaa gtattataac cggacgttgg tttcacagaa aaacatctat ttgtaaagtc
     4861 tacgttacca acgcccgatt ataaaaactt acactcttag gagatgatca gatctcaata
     4921 tcccaaatac ccgccgaacg ttctaattcg accaaggctg agctgtaatt aaacagcgtc
     4981 tcaatatact gagcttgtac ttcatcgtaa gtacgctggg cgtccaagac ttccaacaaa
     5041 gagacttccc ccctattata gctgtaaatc ttgccatcca tcacctcacg ggcttgcctt
     5101 aaaagcccat cctgataatg attgacttgc tcggcgaaag attgataatt acgatatgcc
     5161 tgcatcacct ccgtctgtac ttgcaaaaga gcctgcttat attgcgcttc cgcttgttgc
     5221 tcccgataac gagcggcacg aaccgtcccc ttattgaaat tagagaattt caaaggaaca
     5281 gcgatacctg ccgtcactcc ggtaaaagga ggtgccgggg cttcctcatt ataaacccgg
     5341 gcgttacggc ttacggcgat agacaaatcc acatccgtat tccgctcccg gcgagctact
     5401 ttcaaggctc tagcggccac ttccttgttt tttaaggcgg ctaccaaatc cgtacgcccc
     5461 tcgcttgccg ccgtgattaa gtcggcaaga ataaaatccc gaggctccgt acgtaactca
     5521 gcctctgggt gaaataaagt atccgtactg aaagtccccg tcaagaagtt taagttcgag
     5581 aaagcattct ttaattccgc tccggcttgc agcaactcgt ttcgtaagac cccggcctct
     5641 acccggctct gcgtagcatc cacctcacgg atttgcccca atgagaaacg gatactgtcg
     5701 ctctccgcca atgtccggat attctcatag gcattctcct ttaccttata caactcatgt
     5761 tgcttcaagg cttccatata agcaatcgta gcgtctgccc ggagattccg gaaataatcg
     5821 gccaacaaag cctcggtcaa ctcactctcg ctacgtgcca atgagatatt cgcaccccgt
     5881 tttccaaaag agaaagtttt gctcagttct acttcaacac cttctcccat ttgcaaggaa
     5941 ttattctcat tattgaaata agacacggaa aggttcggat cgttaaacac ctttgccgcc
     6001 gttacctcgg ccttagcggc cggcacattc aatttctccg acgcatactc aaggttacct
     6061 tccgcaaccc gctccatata ttgccgatac gtaagcggaa ccatggtctg ggcattcgca
     6121 gataagcatc cgcagagtaa cgacaggatt atatatttct tcatatcttc taatctaaac
     6181 atagtacatc tttttaattc caccgccgga ttaagcgtgc a
//
LOCUS       DBMDTB010000152         6158 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_3245_length_6158_cov_13.586759, whole genome shotgun sequence.
ACCESSION   DBMDTB010000152 DBMDTB010000000
VERSION     DBMDTB010000152.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 6158)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 6158)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6158
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_3245_length_6158_cov_13.586759"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..680)
                     /locus_tag="ACZPB4_15960"
     CDS             complement(<1..680)
                     /locus_tag="ACZPB4_15960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding domain-containing protein"
                     /protein_id="HIR1099748.1"
                     /translation="MAEEKTILTVDLYDNVLTEKAGDYTGKIRITGTTRTSDISNRIV
                     KKRTEYRPETITNILDLSYDEMIEALAQGRCVVNKFGQWLLTINGSFDGKKSDFRSTE
                     NKITVMFTPSATLLKALENIYVNADVATVGPMIESLTDSTTKEKNLHITPNAPAIIFG
                     STLLIKGDDPSVGVYFTKDEEGATPTKASLIVRNTKSEIIIQIPQLAEGQYWLSVTTQ
                     AGANYGLV"
     gene            complement(1040..1987)
                     /locus_tag="ACZPB4_15965"
     CDS             complement(1040..1987)
                     /locus_tag="ACZPB4_15965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009009 - site-specific recombinase
                     activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HIR1099749.1"
                     /translation="MSKRKNNRLGKAGITFYTYATERIREKRLAGKHNTADLYRTTRN
                     WICAFLGRRNLLFPEITPGLISRFVAYLQSAGLRVNTVNTYLSNFRSIYNQACRDGLL
                     PACVVSPFAYLNLKRERAGSRALGNESLREIVTLKSEEPDLACVIDYCTFAYLSCGMP
                     FADMARLTTANLYGEEIVYRRKKTGTLIRVGITAGMRRLINKYADASSPYLFPILSPG
                     REVGHEEYKAILRSYNNSLKKIGRALSRPIHLTSYVFRHTWATNALRKQVPLSIISQA
                     LGHTSEKTTRFYLASLEQSELNRANARVTEEVDLLLAAG"
     gene            complement(2050..3792)
                     /locus_tag="ACZPB4_15970"
     CDS             complement(2050..3792)
                     /locus_tag="ACZPB4_15970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HIR1099750.1"
                     /translation="MATKQIPYGLTDFERIRTANYYYVDKTRYIAEVERNASFFFLIR
                     PRRFGKSLFLNVLRWYYDVNRKDSFEELFGDLYIGSHPTPEQGQYLVLDFNFAGVNPD
                     PDELIRSFNDHCAARFREFAYYYERFFNPGFREKMESLPNADEKLTYTISEAKRLNLS
                     IYLFIDEYDNFTNAILANMGEKHYKALTHGTGFFRYFFNKLKEGATGDGPIKRMFITG
                     VSPVTMDDVTSGFNIGANMTTDYRFNGIIGFSEGEVREMLAYYKSETGFEDSVDDLIN
                     LMKPWYDNYRFSTKSLDEPMYNSDMVLYFISNYLPLRSAPDKMIDNNIRTDYNKLRHL
                     IRLDKRFGTNASIIQEIVNNGETTAVIKDAFPAEDIAKPDNFKSLLYYFGLLSIKGTK
                     RGDTLLGVPNLTVREQLYTYLIEAYREADVFSIELYKLHDLVKDMAYDGDWKPVFEYF
                     SSELERQSAIREFIEGEAHVKGFLLAYLGLTRTYIIYPEYEANKGYADFYMMPDLIHQ
                     PEIGFSYIVEVKYARRDASETEIEALRAEAAIQLRRYAADPKVHATKGDTELRLVTLV
                     FKGWKLAVCEMDLA"
     gene            complement(3921..6122)
                     /locus_tag="ACZPB4_15975"
     CDS             complement(3921..6122)
                     /locus_tag="ACZPB4_15975"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HIR1099751.1"
                     /translation="MKKLLFQTTLFLLLCSCISKIEKTPVDYVNNRIGNISHLLVPTY
                     PTTHLPNSMLRMIPTHNEFTTDRMEGLALNSPSHRQGHSLLLLPYRGDVKDFDGNLKY
                     RYDHEKSTPYNYSVYLDDFSVGVDFVPAAKSAIYRFRFEDSDRRLILLKANGKGEIDI
                     KDGALCGYDNFAGIKHYFYLEFDAQPIQVDSLSHSLVFAEFPESKDVVNVRYGISYIG
                     VEQAKRNLYNEINDFNLEKLASQARDKWNDVLGKIKIEGGTEDQKTTFYTALYRAHER
                     MINISEDGKYFSAYDGKVHEDNGVDFWVDDWVWDTYLALHPLQVLLNPEAQEQKLASY
                     IRMYEQSGWIPTFPCVFGDAHCMNGNHAAGVFADALNKGLRFDVEKAFEGMKHTVMTE
                     SMIPWYRGPKTALDDFYHENGWFPALHPGEKEEFTEVGPFEQRQAAAVTTAASYDDWC
                     IAQLAKHLGKDEDYRFFQDRSYNYRNVFNKETHFFHPKDKDGKFIEPFDYIFSGGIGA
                     RAYFDENNAWTYNWDVRHHIQDLIDLFGGNTPFIERLDQLFVEDMKMSKWQYYALHPD
                     ATGNVGQFVMGNEPSFHIPYLYNYAGQPWKTQKRIRMLMESWFRNDLMGVCGDEDGGG
                     MSAFYVFSALGFYPVSPGVPVYTIGSPLFDKSEIQLANGKVFTMIAHGVSWENKYIQS
                     AKLNGAEYNKTWFTHEDVMKGGTLELFMGDRPNKKWGVGEGANPPSGEFVD"
BASE COUNT         1660 a         1574 c         1290 g         1634 t
ORIGIN      
        1 ttcaccaagc cgtaattcgc ccccgcctgc gtagtgacgc tcagccagta ctgcccctcg
       61 gcgagttgcg ggatctggat aattatctcg ctcttggtgt tacgtacgat aagggaggct
      121 ttcgttggcg tggcgccctc ctcgtccttg gtgaagtaga cgcctacaga tggatcatcc
      181 cccttgataa gcagcgtgct gccgaagatg atggccgggg cgttcggagt gatatggagg
      241 ttcttctcct tcgtggtaga atccgtgagg ctctcgatca tcgggcccac agtggctacg
      301 tcggcgttca cgtagatgtt ttctagcgcc ttcaggaggg tggcgctggg ggtgaacatt
      361 acggtgatct tattctccgt agagcggaag tctgatttct ttccgtcgaa cgagccgttg
      421 atagtgagca gccattgccc gaacttgttc accacgcaac ggccttgggc gagggcctcg
      481 atcatctcgt cgtaggagag gtcgaggatg ttggtgatcg tctccggacg atactcggta
      541 cgtttcttca cgatgcggtt cgagatgtct gaggtccgcg tggttccggt gatgcggatc
      601 tttccggtgt aatcaccggc tttctcggtt aacacgttgt cgtacagatc tacggtcaag
      661 atggtctttt cttctgccat gatgtttttt gtctttaatg ccccgtggta gtgaggcgtt
      721 accttttaat aatgtttatc acccttattc gcgaaataag gggaggagcc tatcgcacgt
      781 ccaacataaa ctaaaaaaac acgcataacc actattttta accgcatatc cacgatatat
      841 gcgcaataag cataaatttg gattaattag aggatacgat atctgtatcc ccttcaattc
      901 ctatttctta ataaatagat aaaagtgatt gtttatcaat aatatttttt acatttgcca
      961 agccttccgt tgaaaatagc ctattatagg taatttttat gcagaatagg ctcctcccct
     1021 tatttcgcga ataagggcat catccagccg ccaaaagcaa atccacctct tccgtcaccc
     1081 tagcgttcgc acgattcaat tccgactgtt ccaaagaggc cagataaaaa cgtgttgttt
     1141 tttccgaggt atgccccaac gcttggctaa tgatcgataa agggacttgt ttccgcaagg
     1201 cgttcgttgc ccatgtatgg cggaaaacat acgaggtcag atgaatggga cgagatagcg
     1261 cacgaccgat cttcttcaac gagttattat acgaacgcag tatcgccttg tattcctcat
     1321 gccctacctc tctacccgga gataaaatag ggaaaaggta cggggaagaa gcgtccgcat
     1381 acttattaat caaccgccgc atccccgctg ttatcccgac acggattaag gtccccgtct
     1441 tcttacgccg atatacgatc tcctcgccat acaggttcgc cgtagtcaag cgagccatat
     1501 ccgcgaaagg catgccgcaa gataaatagg cgaacgtaca atagtcgatc acgcacgcca
     1561 aatccggctc ctcagacttc aaggtcacga tctcccggag cgactcgttt cccaacgccc
     1621 tagatccggc tctttcccgc ttcaagttca agtacgcgaa aggcgatacg acgcaagccg
     1681 gcaacagacc atcccgacaa gcttggttat aaatcgagcg aaagttgctg aggtatgtat
     1741 tcacggtatt cactcgcaag ccggcggatt gcagataagc gacaaaacgg cttattaagc
     1801 ccggggttat ctccgggaaa agaaggtttc tcctacccag aaaggcgcag atccaattac
     1861 gggtcgtcct atataaatcg gcagtgttat gtttccccgc taaacgtttc tcccggatgc
     1921 gttcggtggc ataggtataa aatgtgatgc ccgccttgcc caagcggtta ttctttctct
     1981 tgctcatatc tccttttttg atgattaaac gtattattat ctaccatcaa aaatagcata
     2041 aaaacaaaat caagccaagt ccatctcgca aacagcaagc ttccaaccct taaagaccaa
     2101 ggtgacaaga cgaagctccg tatccccctt agtagcgtga accttcgggt ctgcggcgta
     2161 acggcgtaac tggatggcgg cctcggctct caacgcctcg atttccgttt cggaagcgtc
     2221 ccgacgggcg tatttcacct ccacgatata gctaaagcct atctcgggct ggtggatcaa
     2281 gtcgggcatc atgtagaaat cggcgtaccc cttgttggcc tcatactccg gataaattat
     2341 ataggtacgg gtcaagccta gataagccag taggaaacct ttcacgtgcg cctccccctc
     2401 tatgaactcg cggatagcgc tctgccgctc cagctcggag gaaaaatact cgaacacagg
     2461 cttccagtct ccgtcgtaag ccatgtcctt taccagatca tgaagcttgt ataactctat
     2521 tgagaagaca tcagcttccc ggtaagcctc gatcagatag gtatataatt gctcacgtac
     2581 cgtcaggttg ggaacgccca gaagggtatc tccacgcttg gtacccttga tggagagcaa
     2641 cccgaaatag taaagcaggc tcttgaagtt gtccggcttg gcgatatcct cggcaggaaa
     2701 agcatccttg attactgcgg tggtctcgcc gttgttcacg atctcctgga tgatcgaagc
     2761 gttcgtgccg aaccgcttgt cgagacggat caaatggcgg agcttgttgt agtccgtgcg
     2821 gatgttgttg tcgatcatct tatccggggc cgatctcaag ggcaggtaat tgctgatgaa
     2881 atacagtacc atatccgagt tgtacatagg ctcgtccaga ctcttcgtag agaaacggta
     2941 gttatcgtac cacggcttca tcaagttgat cagatcgtcc acactatcct caaaacctgt
     3001 ctcgctcttg taataggcca gcatctcccg tacctctccc tcgctaaaac ctatgattcc
     3061 attaaagcgg taatctgtcg tcatgttggc tccgatattg aaaccgctgg tcacgtcgtc
     3121 catcgtcact ggagataccc cagtgataaa catgcgcttg atagggccat cgcccgtagc
     3181 cccttctttc agtttgttga agaaataacg gaagaagccc gtaccgtgtg tcaatgcctt
     3241 gtaatgcttc tcacccatat tggcgaggat agcgttggtg aagttatcat actcgtcaat
     3301 gaagagatag atagagagat tcaagcgttt agcctcactg atcgtgtagg tcaacttctc
     3361 gtcagcattt ggcagactct ccattttctc ccggaagccc ggattgaaga aacgttcgta
     3421 gtagtaggca aactcccgga aacgagcggc acagtgatca ttaaaagagc ggatcaactc
     3481 gtcaggatct gggttcacgc ctgcgaaatt gaaatccagt acaagatatt gtccctgctc
     3541 cggggtcgga tgggagccga tatataagtc gccgaagagt tcctcaaaag aatccttacg
     3601 gttcacgtca taataccatc tgaggacatt caagaatagc gacttcccga aacggcgcgg
     3661 gcggataagg aaaaagaaac ttgcgttccg ctccacctcc gcaatatagc gagtcttatc
     3721 aacataataa taattggcgg tacggattcg ctcgaaatcc gtcaggccat atggaatttg
     3781 cttcgttgcc ataatatatc tcctcctgtt tatttgtcac ttacgaataa atcacttgtt
     3841 cgtaacttac ttacgcaaag ataacatcta caaaatgatt tcacgaatct ttgaccgtag
     3901 aatcatgccg tcaaaccaaa tcaatcgaca aactcaccag aaggaggatt cgcaccttct
     3961 cccactcccc acttcttatt agggcggtct cccataaaca attctaatgt tcctcccttc
     4021 atgacatcct catgagtaaa ccacgtctta ttatactcgg cgccattcaa cttagcggat
     4081 tgaatgtatt tattttccca cgaaacccca tgagcgatca tggtaaacac tttcccgttc
     4141 gccaactgaa tctccgattt atcaaataaa ggactaccta tcgtataaac aggcactccc
     4201 ggagaaaccg gatagaaacc taaagcggag aatacataga aagccgacat tccaccacca
     4261 tcctcatcac cacaaacacc catcagatca ttcctgaacc aactttccat aagcatacga
     4321 atccgttttt gcgtcttcca cggttgaccg gcgtagttat acagataagg aatatggaaa
     4381 ctaggctcat ttcccatcac gaattgcccg acattgcccg tagcgtccgg atgaagagcg
     4441 taatattgcc attttgacat tttcatatcc tcaacaaata actgatccaa tctctcaata
     4501 aaaggagtgt tgcctccaaa aagatctatt aaatcctgaa tatgatggcg tacatcccaa
     4561 ttataggtcc aagcattatt ctcatcaaaa taagccctag ccccgatacc tccggaaaaa
     4621 atatagtcga acggttctat aaacttccca tctttatcct tcggatggaa gaaatgagtc
     4681 tctttgttaa agacattccg gtaattataa gaacgatcct gaaagaatcg ataatcctca
     4741 tcttttccca aatgtttagc taattgggcg atacaccaat cgtcatagga tgcggctgta
     4801 gttacggctg ccgcttgtcg ctgttcaaat ggtcctacct ccgtaaactc ttctttttct
     4861 cccggatgca aagcggggaa ccagccattc tcatgataaa aatcatccaa ggccgtttta
     4921 ggtccccggt accaagggat catggactca gtcatcaccg tatgcttcat accctcgaaa
     4981 gccttttcca cgtcaaaccg caagccttta ttcaaggcat ccgcaaagac acctgccgca
     5041 tggttaccgt tcatgcaatg cgcatcccca aatacacaag ggaaagtagg tatccacccg
     5101 gattgctcat acatccggat ataagacgcc agtttttgtt cttgagcctc cggattcaat
     5161 aacacttgca acgggtgaag ggccagatag gtatcccata cccaatcatc cacccaaaaa
     5221 tccaccccat tatcttcatg tacctttccg tcatacgcac taaaatattt accatcttca
     5281 gaaatattga tcattctttc gtgcgcccga tacaaggcgg tataaaatgt ggtcttttga
     5341 tcctccgtgc ctccttcaat ctttattttg cctaacacgt cgttccattt atcacgagct
     5401 tgcgaggcca atttctccag attgaaatca ttgatttcat tatataaatt ccgcttggcc
     5461 tgctctactc caatataaga aattccataa cgaacattta ccacatcctt cgattccgga
     5521 aattcagcaa ataccaaaga atgagagagg ctatcaactt gaatgggctg ggcatcaaac
     5581 tccaaataaa aataatgttt tatcccggcg aaattatcat atccacacaa agctccatcc
     5641 tttatatcga tctctccttt tccattggct ttcaacaaaa tcaaccgtcg atccgaatcc
     5701 tcaaaccgaa aacgatagat cgccgattta gcagcaggca caaaatccac ccctacggag
     5761 aaatcatcca aatacaccga ataattataa ggcgtagatt tctcatgatc atatcgatat
     5821 tttaaattcc catcgaaatc cttaacgtcc cccctataag gcaacagcaa caatgaatgg
     5881 ccttgcctat gggaaggact atttagggcc agtccctcca tacgatccgt cgtaaactca
     5941 ttatgagtcg gaatcattcg caacatgctg ttaggcaggt gggtagtggg ataggtaggc
     6001 acaagtaaat gactgatatt cccaatccgg ttattcacat aatctactgg tgttttttct
     6061 attttactta tgcaactaca taataataga aacaaggttg tctgaaataa tagtttcttc
     6121 atgagattgt atttaataat aacgattctc tagcatct
//
LOCUS       DBMDTB010000153         6048 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_3305_length_6048_cov_10.777703, whole genome shotgun sequence.
ACCESSION   DBMDTB010000153 DBMDTB010000000
VERSION     DBMDTB010000153.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 6048)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 6048)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6048
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_3305_length_6048_cov_10.777703"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..1553)
                     /locus_tag="ACZPB4_15980"
     CDS             complement(<1..1553)
                     /locus_tag="ACZPB4_15980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HIR1099752.1"
                     /translation="MEGRRLYPIGIQTFSKLREGNYVYVDKTELVYRMTHGASGYIFL
                     SRPRRFGKSLLTSTLHSYFEGRKELFEGLAIEHLEKEWTRYPVLHFDMSTAKHMDKDR
                     LLSELERKLYGYEQIYGRDESAIYTNQRLESLIKRAYAQTGQKVVVLIDEYDAPLLDV
                     VHEEKELPKLRDVMRNFYSPLKACDPYLRFVFLTGITKFSQLSIFSELNNIKNISMLP
                     EYASLCGITEEEMREQMGEDIGRLADNLGVTPEGALGALKSNYDGYHFTWPSPDIYNP
                     FSLLNALADSKLNSYWFGSGTPTYLIEMLNKYHVKPQQIGARKFLAESFDAPTERMVD
                     ITPLLYQSGYITIKDYSSLTNLYTLDIPNKEVRMGLMKSLLPNYLHQYTADGLTTVAL
                     LFEAISGERMDDALRLLQTFLSTIPQCDNTDYEGHYQSLLYTIFSLLGMYVDVEVRTP
                     KGRVDMVMRTPTTLYVVELKLNKTADIALEQINLRNYPERFALCGLPIVKVGINFDSE
                     RHTLGDWVI"
     gene            complement(1701..1901)
                     /locus_tag="ACZPB4_15985"
     CDS             complement(1701..1901)
                     /locus_tag="ACZPB4_15985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099753.1"
                     /translation="MKENLDLNQILFDELVEFPRKRLGISIREFCAEAHVGTATYSKA
                     KKKEYQSPESDPLGTRTMRRDG"
     gene            2011..2553
                     /locus_tag="ACZPB4_15990"
     CDS             2011..2553
                     /locus_tag="ACZPB4_15990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BT4734/BF3469 family protein"
                     /protein_id="HIR1099754.1"
                     /translation="MDQQMSYFLPPITNTLPTGNCTLREVYRWITEDKSLETVTNELR
                     AFIREGRIAEYRQLKQRQLPFVTPHGIFSRRKSDALISASGLVVVDIDHLASLEEAEQ
                     LRNHLFEDPYLGTRLAFVSPGGLGVKLFIPGDETVRWAMSYIQLLYADTFKGEVDTCG
                     KDIARCCFLSHDSNAKIFIP"
     gene            2550..4340
                     /locus_tag="ACZPB4_15995"
     CDS             2550..4340
                     /locus_tag="ACZPB4_15995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012056186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3987 domain-containing protein"
                     /protein_id="HIR1099755.1"
                     /translation="MNNDLSKLVEAVRTAHADIAPTYAEYVQLAFAIATDCGEAGRSD
                     FISLCEPSPKFNALHANKLFSSALRTGNQNVHLGTAFHLAKLAGVEIGFKFQGFTKPF
                     SSHTRVSTYNIADTVDQAHETSNRETEANDAPLHIGSEPYTSLPRLVPGYPWPSLLRD
                     ILGFADNAEQRDILLLTALTALGATLGKTVRCLYGMHWIYPCIQLFVIAPPASGKGIM
                     AWLRKFIEPIHREIRQQVDLAMKQYRQDLAAYHALGKEKAKMEMPQMPKNSMFIISGN
                     NTGTGILQNIIDSDGTGIIFETEADTITTAIGGDYGHWSDTLRNAFDHAGLSFNRRTD
                     NEYRECDSTFLSMVLSGTPGQVAPLIPSGENGLFSREVFYYKSQIREWIDQFSVDEVD
                     AEKEFHRMGYEWKATIDQLKCRGTITLRLDERQQAAFNDSFVRLFLRARQSNGQEMNS
                     SVVRLAINLVRFMEVVAMLRALEQPELLLPAQGINSDNLKDKIIGGWELHITDDDFAA
                     LLTMAEPLYLHATHILSFLPTGEITSRGLSEKDSLLSSMPDEFTTVQWMEAAEHANIP
                     KNTAKTWLRRLCDSGAILHGEHKGIYLKPL"
     gene            4426..4620
                     /locus_tag="ACZPB4_16000"
     CDS             4426..4620
                     /locus_tag="ACZPB4_16000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4248 domain-containing protein"
                     /protein_id="HIR1099756.1"
                     /translation="MKKIDLARQYCLTGTPSNALHKLNRYIRDVKGLKEALIRHGYHS
                     KDRSITPKQVQIFYDFLGEP"
     gene            4722..5147
                     /locus_tag="ACZPB4_16005"
     CDS             4722..5147
                     /locus_tag="ACZPB4_16005"
                     /inference="COORDINATES: protein motif:HMM:NF019896.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase family
                     metallohydrolase"
                     /protein_id="HIR1099757.1"
                     /translation="MRYFNYQEFEDSATARRDGIDNSLTPVARRMVTILVEMLLDPLR
                     RVWGSPIVISSGYRCPELNILIGGAKHSHHLLGCAADLIAGSPDDHRLLFRLIQETHE
                     LCGLEFTQLILEPGARWIHISYVPGNLRCQVIDKEKSPN"
     gene            5268..5759
                     /locus_tag="ACZPB4_16010"
     CDS             5268..5759
                     /locus_tag="ACZPB4_16010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012056184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HIR1099758.1"
                     /translation="MSLNYSIAMMGNPLKKEEPKKAYAKAQTNGELSLKELSTLIASK
                     CTVHQADVSAVLIATTECMLEGLKAGKQVNFGDLGAFRLQINSGGAPSADLFTSDYIK
                     GVNIQFVPGEELQVIFQGLKFNLVPTRAAQAAVIKAQKAGKTTVDISGKNGSSDSESP
                     DEI"
     gene            5826..5933
                     /locus_tag="ACZPB4_16015"
     CDS             5826..5933
                     /locus_tag="ACZPB4_16015"
                     /inference="COORDINATES: protein motif:HMM:NF040440.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="smalltalk protein"
                     /protein_id="HIR1099759.1"
                     /translation="MSEKKKTNVWSVIIKVVIAIATTIAGALGISACAF"
BASE COUNT         1523 a         1738 c         1398 g         1389 t
ORIGIN      
        1 tcgataaccc aatcccccaa cgtatgccgc tcactatcaa aattaatccc aacctttacg
       61 atcggcaacc cacaaagagc gaagcgctcc gggtaattgc gcaaattgat ttgctcaagg
      121 gctatatccg cagtcttgtt taacttcaat tccacgacat agagtgttgt cggtgtgcgc
      181 atcaccatat ccacacggcc tttcggggta cggacttcca cgtccacata cattcctagc
      241 aggctgaaga tcgtgtaaag caaggactga taatggccct cgtaatccgt attgtcacat
      301 tgggggatgg tggacaggaa ggtctgcaac agacgcaggg catcgtccat ccgctctcca
      361 gagatcgcct cgaaaagaag ggctaccgta gtaagtccat ccgctgtgta ttgatgcaaa
      421 taattgggca ataaactctt catcaatccc atacgtacct ccttgtttgg gatgtcgagc
      481 gtgtacaaat tcgtgagcga ggaataatcc tttattgtga tgtaaccgct ctgatagagc
      541 aatggcgtaa tatcgaccat ccgttccgtg ggtgcgtcaa acgactctgc caaaaacttg
      601 cgtgcgccta tttgctgggg tttcacgtga tacttgttca gcatctcgat caaataggtg
      661 ggcgtaccgc taccgaacca ataggaattt agtttactgt cggccaaggc gttcaacagg
      721 ctgaacggat tgtatatatc gggcgagggc cacgtgaaat ggtaaccgtc ataattcgat
      781 ttcaaggcac ccaaggcacc ctccggagta acgccgaggt tgtcggccaa acgaccgata
      841 tcctcgccca tctgctcacg catttcctcc tccgtgatgc cacagagcga ggcgtactcc
      901 gggagcatgc tgatattctt gatattgttc aactcgctga agatgctcaa ttgagagaac
      961 ttcgtgatac ctgtcaagaa tacgaaacgc aaataaggat cgcaggcttt cagcggacta
     1021 tagaagttac gcatcacgtc gcgaagcttc ggcagctcct tctcctcatg caccacgtcc
     1081 agcaagggag cgtcgtactc gtcgatcaag acaaccacct tttgaccggt ctgggcgtag
     1141 gcacgtttga tgagactttc cagacgttgg ttcgtataaa tagcgctctc atcacgtccg
     1201 tatatctgct cgtaaccata caatttcctc tccagctcac tcagaagccg atccttgtcc
     1261 atatgcttcg ccgtactcat gtcgaaatga agcaccggat accttgtcca ctccttctcc
     1321 aggtgctcga tggccaagcc ctcgaacaat tcctttcgcc cctcaaaata actatggagc
     1381 gtagaagtaa gcaacgactt cccgaagcgg cggggacggc tcaagaatat ataaccagac
     1441 gcaccgtgtg tcattcggta gaccaattcc gtcttatcta catacacata attcccctct
     1501 ctcaatttgg agaatgtctg tatccctatc ggatataatc gccgcccttc catcttcgtc
     1561 tctgtttatt ggttcgtcaa gacaaatata acgttatttc cctaaacgat caattttcaa
     1621 ccctctattt ttctattcca cgcctcatcg ccctatacac ctccttgagc gccccggccc
     1681 cataccccat gaactccggt tcatccatct ctacgcatag ttcttgtacc aagcgggtca
     1741 gactctgggg attgatactc tttttttttc gctttgctgt aggtggcggt gcctacgtgg
     1801 gcctccgcac aaaactcacg gatggagatt cctaaccgct tacgtggaaa ttccactaac
     1861 tcatcaaata aaatctggtt caaatctaaa ttttccttca tactatgcta attttcatta
     1921 aacaatcatc caatatttca gcctataggc tgaaacgcag aatcaattat tagcaatagc
     1981 tttagaaaat taatctgaaa tcctattgat atggaccaac aaatgtctta cttccttcct
     2041 cccatcacca acacgcttcc taccgggaac tgtacactac gggaagtgta ccgatggatc
     2101 accgaggata aatctctcga aacggttacc aacgaattac gcgccttcat ccgggaaggc
     2161 cggatagcgg aataccgcca actcaaacag cgacaactgc cgttcgtaac gccccacggc
     2221 attttttccc gtcgtaagag cgacgctctc atctccgcct cggggttggt agtggtcgat
     2281 atcgaccatc tcgcctctct cgaagaggcc gaacagctcc ggaaccacct cttcgaggac
     2341 ccctatctcg ggacccgcct cgcctttgtc agccccggag gactgggagt gaaacttttc
     2401 atacccggag acgagaccgt tcgatgggcc atgagttaca tacagctcct gtatgccgac
     2461 accttcaagg gtgaggtgga tacctgtggc aaggatatcg cccgctgctg tttcttgtct
     2521 cacgattcta acgctaaaat attcatacca tgaacaacga tctttccaaa ctagtagaag
     2581 cggtacggac ggcccatgcc gacatcgccc ccacttacgc cgagtatgta caattggctt
     2641 tcgccatcgc caccgattgc ggggaggcag gacgtagcga cttcatcagt ctctgcgagc
     2701 catcgcccaa gttcaacgcc ctacacgcca acaagctttt ctccagtgcc ttgcgcaccg
     2761 gaaaccagaa tgtccatctg ggcaccgctt tccacttggc caagctggcg ggcgtggaaa
     2821 taggtttcaa gtttcaaggt ttcacgaaac ccttttcctc acacacacgt gtgagtacat
     2881 ataatatagc cgatacggta gatcaagccc acgagaccag caatcgggaa accgaggcaa
     2941 acgacgcccc actccacatc ggcagtgagc cttacacctc cctgccacgg ctggtacccg
     3001 gctatccatg gccctcgttg ctacgggaca tcctcggttt cgccgataat gccgagcagc
     3061 gggatatcct tttgctcacg gctctcaccg ccctaggcgc caccttgggc aagacggtgc
     3121 gttgcctcta tgggatgcat tggatctatc cctgtatcca gctcttcgtg atcgctccgc
     3181 ccgcatcggg taagggcatc atggcgtggc tgcgtaagtt tatcgagcct atccaccggg
     3241 agatccgcca acaagtggac ctagcgatga aacagtaccg ccaagatttg gcggcctatc
     3301 atgccttagg caaggagaaa gccaagatgg agatgcccca gatgcctaaa aacagtatgt
     3361 ttatcatctc cggcaacaat accgggacag gtatcttgca aaatatcatc gattcggacg
     3421 gcaccggtat cattttcgag accgaggcgg ataccatcac caccgctatc gggggtgatt
     3481 acgggcattg gagcgatacg ctccgtaacg ctttcgacca tgccgggctc tcgttcaacc
     3541 gacggaccga taacgaatac cgggaatgcg actccacctt cctctcgatg gtgctctcgg
     3601 gtacgcccgg acaggtagcg ccgcttatcc cctcgggcga gaacgggctc ttcagccgtg
     3661 aggtcttcta ctacaaatcg cagatccggg aatggatcga ccaattctcc gtcgacgagg
     3721 tagacgccga gaaggaattc caccggatgg gctacgagtg gaaggccacg atcgatcagc
     3781 tcaagtgccg gggtaccatt accttgcgcc tcgacgagcg gcaacaagcc gctttcaacg
     3841 acagcttcgt acgtcttttc ctgcgtgccc ggcaatccaa cgggcaggag atgaacagtt
     3901 ccgtggtacg cctcgccatc aacctcgtac gtttcatgga ggtggtagcc atgcttcgtg
     3961 ccttggaaca accggaatta ctgctgccgg cccaaggcat caacagcgac aacctaaagg
     4021 acaagatcat tggaggctgg gaactccata tcaccgacga tgacttcgcc gcccttctga
     4081 caatggcgga gccgctctac ctccacgcca cccatatcct ctcattcctg cctaccggcg
     4141 agatcaccag ccgaggcctc tcggaaaagg acagtctgct cagctccatg ccggacgagt
     4201 tcaccaccgt ccaatggatg gaggccgccg agcatgccaa catccccaag aacaccgcca
     4261 agacatggct acgccgacta tgcgactccg gagccatcct gcatggcgag cataaaggga
     4321 tttatttgaa acccttataa cgtacgtacg tgtgtgtgag gaaagagggt tcatgaaacc
     4381 ttgaaacttg aaactctcct atagtcattt taaaattcaa tacagatgaa aaaaatagat
     4441 ctcgcccgtc aatattgcct gacaggcacc ccttcgaacg ctttgcataa gttgaaccga
     4501 tatatccgtg acgtgaaagg actgaaagag gcccttatcc gtcatggtta tcactcgaaa
     4561 gaccgctcca tcacgccgaa gcaagtacag atattctatg attttttagg ggaaccctaa
     4621 aattcttctc ctagagcgaa taggtggaaa caaatggtat atccgggctt tccgcctatc
     4681 gtatctttgc tacagaaaca aaaacatcaa ccttgtcccc tatgcgctac tttaattatc
     4741 aagagtttga agactccgcc acggcccggc gagacgggat cgacaacagc ctcaccccgg
     4801 tggcccggag gatggtcacg atcctagtgg aaatgctact agacccgcta cggcgggtct
     4861 ggggcagccc catcgtcatc agtagcggct atcgctgccc cgaattgaac atccttatcg
     4921 ggggagccaa gcacagtcac cacctcctcg gttgcgccgc cgacctgata gccggctctc
     4981 cagatgatca tcgcctcttg ttccgactga tacaagagac gcacgagctg tgcggactcg
     5041 agttcactca gctcattcta gagcccggcg cccgatggat ccatatctct tacgtacccg
     5101 gcaatcttcg ctgtcaggtt atcgataaag aaaagtcgcc taattgactt aagtctttca
     5161 aactgaagac ttaaatcaag gagcacgaaa agccaagtca tcaagcgtga ggactcaact
     5221 catcatcccc caagttcttt atgtatcact taaaatatct tacgattatg tcattaaact
     5281 attccattgc catgatgggc aacccgttga aaaaagagga acccaagaaa gcctacgcca
     5341 aggcgcaaac caacggcgag ctcagtctaa aagagctatc taccctgata gcgagtaaat
     5401 gcacagtgca ccaagccgac gtttcggccg tgctcatcgc caccaccgag tgcatgctgg
     5461 aaggtctgaa agccggtaag caggtgaatt tcggcgatct gggtgccttc cgcctccaga
     5521 tcaattccgg gggagcgccg agtgccgacc tgttcacctc cgactatatc aagggggtga
     5581 acatccagtt cgtccccggc gaggaacttc aagtcatctt ccaaggcctc aagttcaacc
     5641 tcgtccccac ccgggccgcc caagccgccg tcatcaaggc ccagaaggcc ggtaagacaa
     5701 cagtggatat ctccggtaag aacggctcct cggacagcga gagcccggat gagatataac
     5761 ggggcacgct tcggcgtgct cattgataca gacttcgtat tatcaacctt ataaaacaaa
     5821 tttaaatgag tgaaaagaag aaaaccaacg tttggagcgt aatcatcaaa gtagtcatcg
     5881 ccatagccac caccatcgcc ggggccttag gcatcagtgc ttgcgctttc taacgcctta
     5941 tccaagacct cgtacttgga gtgccggctt ttgaactcgg ggacgatcgc cttcatcttg
     6001 cccacgatgg ccatatcgtc cctcgagcgg cctaggccga cgagttca
//
LOCUS       DBMDTB010000154         5965 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_3350_length_5965_cov_11.045532, whole genome shotgun sequence.
ACCESSION   DBMDTB010000154 DBMDTB010000000
VERSION     DBMDTB010000154.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 5965)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 5965)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5965
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_3350_length_5965_cov_11.045532"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..1919
                     /locus_tag="ACZPB4_16020"
     CDS             <1..1919
                     /locus_tag="ACZPB4_16020"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="glycoside hydrolase family 20 protein"
                     /protein_id="HIR1099760.1"
                     /translation="KGIELRAASKSGLFYGEQTLRQLYTSKGIPCVSIQDNPRFPYRG
                     LHLDVSRHFFPKEEVMKLLNVMSYYKLNTLHMHLTDAGGWRIQMDKYPKLTTDVAFRT
                     ESDWQKWWDGKDRKYLPEGTPGAYGGYFTKEDIREIVDYATARHINIIPEIEFPGHSD
                     EVFVAYPELSCAGKPYTTGDFCIGNEKSFTFMEDVLSEVIELFPSEYIHIGGDEAGKG
                     AWKTCPKCQGLMRRNGMKDVDELQSYMIHRAEKFLISKGRKLIGWDEILEGGLAPEAT
                     VMSWRGEEGGIKSARMGHDVVMTPGGYMYFDFYQADPKTQPYAIGGYTPIKRAYSYNP
                     VPVDSLTAEESKHILGVQANTWTEYIKDEKHLEYMMFPRALAVAEIGWTPQEDRSWED
                     FKPRMNANIPVLQRMGINTFTLSDEIETTMEVDTLRREIKVMLDAEKYPAEIRYTTDG
                     SIPAASSRVYNGPIVVKDSADIKAAIFRDGQLQGTPTEKKVDYHRGINKPIHYNSKLY
                     SGYMAGGMNALLDGYRGGLTYLDGRWQGYLNDLDCVVDMGEVTDIHKVSSRFMQLIGP
                     GVYQPGEVELLTSEDGESYISQGVIPTTISNTDKDLSFQEYTFNGDWKARYIRIKAKE
                     ANKGFIFTDEIVIW"
     gene            1960..4203
                     /locus_tag="ACZPB4_16025"
     CDS             1960..4203
                     /locus_tag="ACZPB4_16025"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HIR1099761.1"
                     /translation="MKKQLMTFLLCGSLFATAQQPVDYVNPFIGTSNYGTTNPGAVCP
                     QGMMSVVPFNVMGSEKNRFDKDSQWWSTPYSADNKFFTGFAHGSLSGVGCPELGGLLL
                     MPTTGELNVDYKAYGSEYKDEVAHPGYYSNTLTKYNIKAEATASMRTGLSRFTFPKGE
                     SHILLNLGEGLTNETGATVRIVNDTEIEGSKLLGTFCYNPQAVFPVYFVMKVNKAPKK
                     MGYWKKQREMKGVEAEWDIYSGKYKLYTSYTREMSGDDIGVWFDYDTDEGEAIEVKMG
                     ISYVSIENARLNMNTEQPGFDFDKVRTAASTMWNKDLSKVQVEGGTKDEKTIFYTGMY
                     HLLIHPNILQDVNGEYPMMESLKVGHTTGNRYTVFSLWDTYRNVSTLMTLLYPERQLD
                     IIRTMLDMYRENGWLPKWELYGRETFTMEGDPSIPYIVDAWMRGLRDFDEQTAYEAMR
                     KGATTPGEFNLLRPDANDYFSKGYVPLREQYDNSVSHALEYYIADWNLANFAQALGKK
                     EDAKLFRDRSLGYKHYYSKEFGTLRPILPDGTFYSPFDPKQGENFEPSPGFHEGNAWN
                     YTFYVPHDIKGLAKLMGGDKKFVDHLQKVFDDGNYDPANEPDIAYPYLFSYFKGEAWR
                     TQKLVRQLLKDCYHNAPNGVPGNEDTGTMSAWAIFSMMGFYPACPGDVNYVLTSPTFD
                     KVTIQLDKKFYPKGELVIESKHSNPEAIYIKDVFAGDKKLKGYTISQEDLVNAGTLRY
                     ILEDTHK"
     gene            complement(4297..5223)
                     /locus_tag="ACZPB4_16030"
     CDS             complement(4297..5223)
                     /locus_tag="ACZPB4_16030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HIR1099762.1"
                     /translation="MRQFLYCEAGYVEKNQWLPNSWVNVECPTPEDLQFLMDRFNVPE
                     SFLSDIADTDERPRIEYEGNWLLTILRIPLQNQDHDIPFNTVPIGIITNNEIIVSVCY
                     HKTDLIPDFIRYTQRKELQIKNKYELILRLIHSSAVWFLKYLKQINYAVTEAEKALEK
                     SIRNEDLLALMKLEKSMVFFNTSIRGNEVMLAKLQNIFQEPEYIDKDLVEDVEIELKQ
                     AHNTVNIYSDILTGTMDAFASIISNNVNTIMKRMTSLSIILMVPTLIASFYGMNVPIY
                     MEDMPHGFVVIILLSILLSATAFFIFRKIKWF"
     gene            complement(5549..>5965)
                     /locus_tag="ACZPB4_16035"
     CDS             complement(5549..>5965)
                     /locus_tag="ACZPB4_16035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunoglobulin-like domain-containing protein"
                     /protein_id="HIR1099763.1"
                     /translation="FYLSDNPEDYEEYTRFASRLHEPRPMAEFKGGREAMIRFFEQNL
                     RYPESYKGTGTKVRLFYSFTIDSLGMLQNPVSLPENILYPRDTGKTYDEFRDEALRVL
                     RLMPAWEPAVSRIHGPVSIDTGLFFYFNEEGKCGIE"
BASE COUNT         1517 a         1298 c         1613 g         1537 t
ORIGIN      
        1 agaaggggat cgagttgaga gccgcctcta aatccggatt gttttacggg gaacaaacgt
       61 tgcgccagct gtatacgtcg aaagggattc cttgcgtatc gatccaagat aatccccgtt
      121 tcccgtatcg tggcttgcat ctggatgtct ctcgtcattt cttcccgaaa gaggaggtga
      181 tgaagttatt gaacgtcatg tcttattata aattgaatac gcttcatatg catttgacgg
      241 atgccggtgg ttggcgtatc cagatggata aatacccgaa actgactacg gacgtggctt
      301 tccgtacgga atccgattgg cagaaatggt gggatggaaa ggatcgcaag tatctgccgg
      361 aaggaactcc gggggcatat ggcggttatt ttacgaaaga agatatccgt gagatcgtgg
      421 attacgctac ggctcggcat attaatataa taccggaaat cgaattcccg gggcattcgg
      481 acgaggtgtt cgtggcgtac ccggagttga gttgtgccgg caaaccttat acgacgggtg
      541 atttctgcat cggcaacgag aaatcgttta cgttcatgga ggatgtattg tccgaggtga
      601 tcgagttgtt cccttccgaa tatatccata tcgggggaga cgaggccggg aagggagctt
      661 ggaagacctg cccgaaatgt caaggcttga tgcgccggaa tgggatgaag gacgtggatg
      721 agttgcagag ctatatgatt catcgtgccg agaaattcct gatttccaaa ggccgcaaat
      781 tgatcggttg ggatgagatt ctggaagggg gcttggctcc ggaggctacc gtcatgtctt
      841 ggcggggcga ggaaggggga atcaagtccg cccgcatggg acacgacgtg gtcatgacac
      901 cgggtggtta tatgtatttc gatttctatc aagccgatcc gaagacacag ccgtatgcca
      961 tcggcggtta tacgccgatc aagcgggcgt acagttataa tccagtgcct gtggattcgt
     1021 tgactgccga ggaaagtaag catatcctag gggtacaggc gaatacatgg acggagtata
     1081 tcaaggatga gaaacatttg gagtatatga tgttccctcg tgccttggcg gtcgccgaga
     1141 tcggatggac tccgcaagag gatcgtagtt gggaggattt taagcctcgt atgaatgcga
     1201 atatcccggt tctgcaacgg atgggtatca atacgttcac gctctcggac gagatcgaga
     1261 ccacgatgga ggtagatacc ttgcggcgag agatcaaggt catgttggat gcggagaaat
     1321 atccggcgga gatacgttac acgacagacg gctctattcc cgccgcctct tcccgggtct
     1381 ataacggccc gatcgtggtg aaagactccg ctgatatcaa ggccgctatc ttccgtgacg
     1441 ggcagcttca aggaacgcct accgagaaga aggtggatta tcaccggggt atcaataagc
     1501 ctatacatta taatagtaag ctgtatagcg gttatatggc gggtggcatg aacgccttgc
     1561 tggacggcta caggggaggc ttgacttatc tggacggtcg ttggcagggt tatttgaatg
     1621 acttggattg cgtggtggac atgggcgagg tgacggatat ccataaggta tcgtcccgct
     1681 ttatgcaatt gatcggcccg ggcgtgtacc aaccgggaga ggtggagttg ctgacatcgg
     1741 aagacgggga gagctatatc tcgcagggag ttatccctac tacgatatcc aatacggata
     1801 aagacctgtc ttttcaggaa tatacgttta acggcgattg gaaagcccgt tatatccgta
     1861 tcaaggcaaa agaggcaaat aagggtttca tctttacgga tgagatcgtg atctggtaag
     1921 tatgaatcaa ttaattatca actaaaatac atttatcaaa tgaagaaaca gttaatgacc
     1981 ttcctgttgt gtggcagtct gttcgctacg gcgcagcaac cggtagatta tgtgaacccc
     2041 ttcatcggta cgagcaatta cggtacgacg aatcccggcg cggtttgtcc gcagggtatg
     2101 atgagcgtgg ttcctttcaa cgtcatgggg tcggagaaga atcgttttga caaggatagt
     2161 caatggtggt ctactcctta ctcggcagac aataaattct ttacgggatt cgcccacggc
     2221 agcttgagcg gtgtgggatg cccggagctg ggaggtttgc tattgatgcc gacgacgggc
     2281 gagttgaacg tggactataa ggcttacggc agtgagtaca aggacgaggt ggctcatccc
     2341 ggttattata gcaatacctt gaccaagtat aatatcaagg cggaggctac tgccagcatg
     2401 cgtacgggct tgagccgttt taccttcccg aaaggggaga gccatatcct cttgaaccta
     2461 ggcgagggct tgacgaacga gaccggcgct acggtacgta tcgtgaatga tacggagatc
     2521 gaggggagta agcttttagg tacgttctgc tataatccac aggccgtatt cccggtttac
     2581 ttcgtgatga aggtaaacaa ggccccgaag aagatgggtt attggaagaa acaacgtgag
     2641 atgaaggggg tagaggccga atgggatatc tactccggca agtataagtt atataccagt
     2701 tatacccgtg agatgagcgg agacgacatc ggcgtatggt tcgattatga tacggacgag
     2761 ggcgaggcta tcgaggtgaa gatgggtatc tcgtacgtga gcatcgagaa cgcccgcctg
     2821 aacatgaata cggagcagcc cggcttcgat ttcgacaagg tccgtacggc ggctagcacg
     2881 atgtggaaca aggatctttc caaggtacaa gtggaaggag gtacgaaaga cgagaaaacg
     2941 atattctata ccggtatgta tcatttgctg atccatccga atatcctgca agacgtgaac
     3001 ggcgagtacc cgatgatgga gagcctgaaa gtaggccata ccaccggaaa ccgttatacg
     3061 gtcttctccc tgtgggatac gtaccgcaac gtaagtaccc tgatgacctt gctctatccg
     3121 gagcgtcaat tagatattat ccgtacgatg ctggatatgt accgggaaaa cggttggtta
     3181 ccgaaatggg agctttacgg acgtgagacc tttacgatgg agggcgatcc ctcgatcccg
     3241 tatatcgtag acgcatggat gcgcggcttg cgtgactttg atgagcaaac cgcttatgag
     3301 gcgatgcgta aaggcgctac taccccggga gagttcaacc tgcttcgtcc ggacgcgaac
     3361 gattatttca gcaagggcta tgttcctttg cgtgagcaat acgataactc cgtatctcat
     3421 gcgctggaat attatatcgc cgactggaac ttggctaatt tcgctcaagc cttgggtaag
     3481 aaagaggatg ccaagttatt ccgtgatcgt tctttaggtt acaaacatta ttatagcaag
     3541 gagtttggaa cactgcgtcc tatcttgccg gacggcactt tctactctcc gttcgatccg
     3601 aaacaaggcg agaacttcga gcctagtccc ggtttccatg agggcaacgc atggaattat
     3661 acgttttatg ttcctcacga tatcaaggga ctggccaaat tgatgggagg cgataagaaa
     3721 tttgtcgatc atttgcagaa ggtattcgat gacggcaatt atgatcccgc caacgagccg
     3781 gatatcgctt atccttattt gtttagttat ttcaagggag aggcttggcg tactcagaag
     3841 ttggtccgtc agttgttgaa ggattgctat cataacgccc cgaacggtgt cccgggtaac
     3901 gaggatacag gcactatgtc cgcttgggct attttctcca tgatgggctt ctatccggct
     3961 tgtccgggcg acgtgaacta tgtattgact tccccgactt tcgataaggt tacgatccag
     4021 ctcgacaaga aattctatcc taaaggcgaa ttggtaatcg agtctaagca tagtaatccg
     4081 gaagcgatct atatcaagga cgttttcgcc ggcgataaaa agctaaaggg ctacaccatc
     4141 tcgcaagagg acttggtaaa tgccggaacc ttgcgttata tcctcgagga tacgcataag
     4201 taagccaaga taaagatata ccgaatttga tatttaccgg acgcagatga caccgacaag
     4261 cacgggtgat ctgcgtccgg tttatttttt gatatcctaa aaccatttga tcttcctgaa
     4321 tataaaaaag gccgtagcgg atagcaagat cgagagcaag atgataacca cgaaaccatg
     4381 cggcatatcc tccatgtaga tcgggacgtt catcccgtag aagctagcga ttaatgtcgg
     4441 aaccattaag ataatggaaa gtgatgtcat acgtttcatg atcgtgttca cgttgttgga
     4501 gatgatagag gcgaaagcgt ccatcgtacc cgtaagaata tcgctataga tatttaccgt
     4561 gttatgggcc tgtttcaact cgatctccac gtcctccact aaatccttgt cgatatattc
     4621 cggctcttgg aaaatattct ggagcttggc cagcatcacc tcattcccgc ggatggaggt
     4681 gttgaagaat accatgctct tctccagctt catcaacgct agcagatcct cgttgcggat
     4741 gcttttctcc aacgcctttt ccgcctcggt gacggcgtaa ttgatttgtt tcaggtattt
     4801 aaggaaccat acggccgatg agtggatcag ccggaggatc aactcatact tgtttttaat
     4861 ctggagttcc ttccgttggg tataacggat gaaatcgggg atcaagtccg tcttatggta
     4921 acatacgctt acgatgatct cattgttcgt gatgataccg atcggcaccg tattgaacgg
     4981 gatgtcatga tcttggttct gcaacgggat acgtaagatg gtaagcaacc aattcccctc
     5041 gtactcgata cggggacgtt cgtccgtatc ggctatatcg ctcaagaatg attcgggtac
     5101 gttaaatcga tccatcaaga attgaagatc ttcgggagtc gggcactcta cgtttaccca
     5161 actgttagga agccattggt tcttctccac ataaccggcc tcacaataaa gaaattgtct
     5221 cattattgcc tcctttcgtg tttaatccga gcagaggatc aatgaaaccc tccgcctcgt
     5281 tagttcatac tctgttctgt ttctagcggg atactgtcgt ccataatttg aaaattactt
     5341 tttacgggtg caaagataat acttttttac gtaagtaaag ttatgtcgct gtatgctgac
     5401 agcaatattg ttgccagttt acgttagcat aggcttactt ctctgagagt attgcgatac
     5461 ttctggtaat agtactggag tactttcatg gaagtacccg agtactgcct aagaagtact
     5521 ccaatacttc ttaggcagta ctggccatct attcaatccc gcatttcccc tcttcgttga
     5581 agtagaagaa gagcccggta tctatgctga ccggaccatg gatacggctt acggcgggtt
     5641 cccatgcggg catcaaccgg agtacccgta aggcttcatc gcggaactca tcataggttt
     5701 tccccgtatc gcgaggatac agtatattct cgggtaggct tacgggattc tgtaacattc
     5761 ctaaggaatc gatcgtgaag gagtagaaga gtcgtacctt cgtgcccgta cctttgtaag
     5821 attcgggata acgcaggttc tgttcgaaga aacggatcat ggcttctctt cctcccttga
     5881 actcggccat ggggcgaggc tcgtggagcc ggctggcgaa gcgtgtgtat tcctcataat
     5941 cttccgggtt atcggatagg tagaa
//
LOCUS       DBMDTB010000155         5949 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_3359_length_5949_cov_13.370212, whole genome shotgun sequence.
ACCESSION   DBMDTB010000155 DBMDTB010000000
VERSION     DBMDTB010000155.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 5949)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 5949)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5949
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_3359_length_5949_cov_13.370212"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            348..2068
                     /locus_tag="ACZPB4_16040"
                     /pseudo
     CDS             348..2068
                     /locus_tag="ACZPB4_16040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860757.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            2238..4277
                     /gene="metG"
                     /locus_tag="ACZPB4_16045"
     CDS             2238..4277
                     /gene="metG"
                     /locus_tag="ACZPB4_16045"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008646565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HIR1099764.1"
                     /translation="MEKHFKRTLITTALPYANGPVHIGHLAGVYVPADIYARYLRLKG
                     EEVLMIGGSDEHGVPITLRAKKEGITPQDVVDRYHGIIKKSFEEFGITFDIYSRTTSA
                     THHQMASDFFRTLYDKGEFIEKTSEQYYDEEAKQFLADRYITGTCPHCGNEKAYGDQC
                     EACGTSLSPTDLIDPKSAISGSKPVMRETKHWYLPLDKWEPFLREWILEGHKEWKPNV
                     YGQCKSWLDMGLQPRAVSRDLDWGIPVPVEGAEGKVLYVWFDAPIGYISNTKELLPDS
                     WETWWKDPETKMVHFIGKDNIVFHCIVFPSMLKAEGSYNLPENVPANEFLNLEGDKIS
                     TSRNWAVWLNEYLVDMPGKQDVLRYVLTANAPETKDNDFTWKDFQARNNNELVAILGN
                     FVNRALVLTDKYFEGKVPAAGELTDYDRQTLKDFADVKENVERLLDTYHFRDAQKEAM
                     NLARIGNKYLADMEPWKLAKTDMPRVATIMNIALQITANLAIAFEPFLPFSMEKLNKM
                     LNVEPLGWNRLGATDLLEAGHQLGKAELLFEKIEDSVIEAQVQKLLDTKKANEEANYK
                     AKPIRENIEFDDFMKLDIRVGTVLECVKVPKADKLLQFRIDDGLEKRTIVSGIAQHYK
                     PEELVGKQVCFIANLAPRKLKGIVSEGMILSAENFDGKLAVITPEKEVKPGSEVK"
     gene            4350..5480
                     /locus_tag="ACZPB4_16050"
     CDS             4350..5480
                     /locus_tag="ACZPB4_16050"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008781060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HIR1099765.1"
                     /translation="MLEKQIQMVDLRRQYERLRSEINPAMQTVIDACAFINGPQVKEF
                     CNHLSGYLGVPYVIPCGNGTDALQISLMALDLHPGDEVIVPAFTYIAAAEVALALGLV
                     PVLVDVDPGTFNIDPEKIEDALSEKTRAIIAVHLFGQCCDMEPILRIASRHNLYVIED
                     NAQSIGANYTFSDGTVKKACTIASIGTTSFFPSKPLACYGDGGAMFTSDARLAERLRM
                     IANHGQKVKYHHALVGCNSRLDTLQAAVLDVKLRYLDEFAAARCKVAARYDAAFSGLD
                     AVRKPLKSAFSSHVYHQYTVQLAVEKRDQVQAALKERGIPSMIYYPLPLQEQEVMRGR
                     CRISGDLNVASRLSRSVLSLPIHTEMTEEEQAYIIESIKSVL"
     gene            5477..>5949
                     /locus_tag="ACZPB4_16055"
     CDS             5477..>5949
                     /locus_tag="ACZPB4_16055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005864088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family protein"
                     /protein_id="HIR1099766.1"
                     /translation="MNKKIRFAVIGCGHIGKRHAEMITRDEGAELVALCDIRPKEELG
                     IEAYAVPFARDIDELFRLGLDIDVVNICTPNGLHAEMAIQAIESGHHVVIEKPMALTL
                     ADAEKVVYTSLRFRKQVFCVMQNRYSPPSVWIKEMVESGKLGQIYMVQLNCYWNR"
BASE COUNT         1524 a         1208 c         1579 g         1638 t
ORIGIN      
        1 aaacgtacgt gcgtacatta aaatatacag tctctctctt taaaggcaaa tccaaaaaca
       61 tatccagtta cttttctccc cttttggatt aaaaagtatc ttaactgtat cgttcaacga
      121 aactaagtgt gttggccaag tatcttagtt tcgttggcca atgcacctag gtgcaaatat
      181 gtattaaagc atatggacaa tttccatccc tcgtgcccca accgttattc gcaaattatt
      241 ccttaccttt ccttgataaa agaagattac tcagcgaaca ggtataagaa ttggagattt
      301 ttatctaagt ttgtcagtat acatcaaaaa gaaaggaaga tcctatgata cctcagataa
      361 ccattcccta tgccgtggct gatttcgctg aaatatgcga acgtggcttt tgctatgtgg
      421 ataaaactcg gtttatccct tatttggagc ggtataaggc tccggtgttt ctgcgtccgc
      481 ggcgttttgg aagagcttgt tggtctctat gctcgcccat tactacgatc gcagtaagtc
      541 tcatcgcttt gaggaacttt ttggggggac ttggatcggg accaatccta cgccggagca
      601 taaccaatac atgattatcc gctacgactt ctcgaagatg gtgatggata gcacgatgaa
      661 cgggttagag cagaatttta atgatctgaa ttgttccccc gtggagatca tggtagagca
      721 taaccgtgat cttttcggtg attttaagtt ctcagtgaga ggtaatgcca ccaagatgct
      781 ggaggaggcg ttggcttatg tccgtatgcg cggcttgccc aaggtttata tccttattga
      841 tgagtacgat aatttcacca accaattgct cacggcctat aaggacccgc tttacgagtc
      901 tgtcaccact ggcgagagct tcttgcgtac cttcttcaag gctatcaagg cgggtatcgg
      961 cgagggaagt atccgtactt gcttttgtac gggtgtgctg cctgttacga tggatgactt
     1021 gacgagcggc tataatatcg ccgaaattct taccttgaag cctgacttca cggagatgtt
     1081 gggtttcaat catgaggagg ctgccgaata cctgcgctat gttattcgta aatatggcaa
     1141 taatgaggat cgtttcgacg agctgtggac gcttatcgta aacaactatg atggctatcg
     1201 ctttctgccc aacgcgcatc cgttatttaa ttccactata ttgacttatt ttttcaagaa
     1261 cttcgccgag ctgtccggtg gtgtccccga tgagatggtg gacgagaacc ttcgaacgga
     1321 cgtgaattgg atccgccgcc ttaccatcat cttggagaac gcgaaggaga tgctggatgc
     1381 cttggtgatc gatggcgagt tgatctactc tcaaccggat cttaggagta agttcaataa
     1441 gcagaagttc ttcgatttgg atttttaccc cgtcagtcta tattacttgg gcatgacaac
     1501 gttgaaagat aattatgtga tggtgcttcc caacttgacc gctcagagca tctacatgaa
     1561 ttattacaac gagttgaatc agattagcga tgacgctcgc tgttttgttc ccgcttatcg
     1621 cctgtttatg gatcatcgga agctgaagcc gcttgtggaa aattatttca aggaatatct
     1681 cggccagttc ccggcgcaag tattcgacaa gatcaacgag aactttattc gttgctcttt
     1741 ctacgaggta ctgagtcgtt acttgagcaa ctgctatacc ttcgccgtgg agcagaactt
     1801 gccaagcggc cgtgcggatc tggtattgac gggcatatcg ggcaccgcct tccacaacga
     1861 ttgccgagtg gtggagttca agtatttcaa ggcgaaagac gctaccatgg tagaggcctt
     1921 gaaggtcgtt cgtcccgaag atgccgatca ggtgagaaga tatgccgctg atatcaatcg
     1981 gcaattcccc gcttaccgca tgcgagcgta tgtggtgtat atagcggcag gaaaagtttg
     2041 taagacatgg gaagttatta atctctaatg taaaggataa gacatgagac atttgttgat
     2101 tattctatta tgtcttgatc ggcaatatat actatgcgat cgaaagagga atatatccat
     2161 ccttgaatga tattccaatc ttttttatct aaccaaatta ttccgtacct ttgcccctca
     2221 aaaagagaac acaaggtatg gaaaaacatt ttaagagaac gctgattact acggcgttgc
     2281 cgtatgcgaa cggaccggtg catatcggcc atttggccgg ggtatatgtg cctgctgata
     2341 tttatgcccg ttaccttcgg ttgaaggggg aggaagtgtt gatgattggt ggttcggacg
     2401 agcatggggt acccatcacg ttgagagcga agaaagaggg gattacaccg caggatgtgg
     2461 tggatcgtta ccacggtatt atcaagaaat cgttcgagga gttcggtatc acgtttgata
     2521 tctattctcg tactacttcc gctacgcatc atcagatggc ctcggatttt ttccgtacat
     2581 tgtatgataa aggcgaattc atcgagaaaa caagcgagca atactacgat gaggaggcga
     2641 agcaattctt ggccgaccgt tatatcacgg gtacttgtcc gcattgtgga aacgagaagg
     2701 cgtatggtga ccagtgcgag gcttgcggta cgtctcttag cccgacggat ttgatcgatc
     2761 cgaaatccgc tatcagtggc agcaagccgg tgatgcgtga gacgaagcat tggtatctgc
     2821 ctttagacaa gtgggagccg ttcttgcgtg aatggatatt agagggacat aaggaatgga
     2881 agccgaacgt atacggacag tgtaagagct ggctggatat gggactgcaa ccccgtgcgg
     2941 tgagtcgtga tttggattgg ggtatccctg ttcccgtgga aggggcggaa ggaaaggtgc
     3001 tgtatgtctg gttcgacgct ccgatcggtt atatctctaa tacgaaagag ttgttgccgg
     3061 atagctggga gacttggtgg aaggatccgg agactaaaat ggtccatttc atcggtaaag
     3121 ataatatcgt gttccattgt atcgtgttcc cttccatgct gaaagcggaa ggttcttata
     3181 acttgccgga gaatgtcccc gctaacgagt tcttgaactt ggagggcgac aagatctcta
     3241 cttcccgcaa ctgggcggtt tggttgaacg agtatctggt ggatatgccg ggcaagcaag
     3301 acgtgttgcg ctatgtcttg acggccaacg cgccggagac aaaggataat gatttcacat
     3361 ggaaagattt tcaggctcgt aataataatg agttggtcgc tatcttagga aacttcgtga
     3421 accgtgcgtt agtccttacg gataagtatt tcgagggtaa ggtgccggcg gctggcgagt
     3481 tgacagatta tgatcgccag accttgaagg atttcgcgga tgtgaaagag aacgtggaac
     3541 gcctgttgga tacctaccac ttccgtgacg ctcagaaaga ggcgatgaac ctagcccgta
     3601 tcggaaataa gtatctcgct gatatggagc cttggaagtt ggcgaagacg gatatgcctc
     3661 gtgtcgctac gatcatgaac atcgctttgc agattacggc taatctggcg atcgcttttg
     3721 agccgttctt gccgtttagc atggagaaac tgaataagat gctgaatgta gagccgttgg
     3781 gatggaatcg cctaggtgct acggatctat tggaggccgg tcatcaattg ggcaaggcag
     3841 agttgttgtt cgagaagata gaggatagcg tgatcgaggc ccaagtgcag aaattattgg
     3901 atacgaagaa agcgaatgag gaagcgaatt ataaggcgaa accgatccgt gagaatattg
     3961 agttcgatga tttcatgaaa ctggatatcc gtgtgggtac ggttctggaa tgtgtgaagg
     4021 ttccgaaagc ggataagctg cttcagttcc gtatcgacga tggcctggag aaacgcacga
     4081 tcgtgtcggg tatcgcccag cattataaac ccgaggaatt ggtaggcaag caagtttgct
     4141 tcatcgctaa cttagctccc cgtaagctga aaggtattgt ttccgagggt atgattctct
     4201 ccgccgagaa tttcgatgga aagctggccg ttatcactcc ggagaaagag gtgaaaccgg
     4261 gtagtgaggt gaaataataa gataaacgca ataatgaggg ggctatttcg ttttaacgac
     4321 gggatagccc tattttttga atggataaga tgctagagaa acagatacag atggtagatc
     4381 tgcggaggca gtatgaacgt ttgcgtagcg agatcaatcc cgccatgcaa acggtgatag
     4441 atgcttgtgc ctttatcaat ggccctcagg tgaaagaatt ttgtaaccat ttatcaggtt
     4501 atttaggtgt tccttatgtg atcccgtgcg gcaacggtac ggatgccttg caaatctcct
     4561 tgatggcatt agacttacat ccgggcgatg aggtgatcgt tcctgctttt acgtatatcg
     4621 ccgcggctga ggtcgctttg gctcttggcc tagtgccggt attagtggat gtagatcccg
     4681 gtacattcaa tatagacccg gaaaagatag aagatgcctt gtctgaaaag acgagagcta
     4741 ttatcgcagt tcatcttttt ggccagtgtt gtgatatgga accgatcttg cgtattgcca
     4801 gccgtcataa tctatatgtg atcgaggata atgcccagtc catcggtgct aattatactt
     4861 tctcggatgg aacggtgaag aaagcctgta cgatcgcctc tataggaacg acctccttct
     4921 tcccttcgaa accgttggct tgttatggtg atggtggggc gatgtttact tccgacgcac
     4981 gattggccga acgactgcga atgatcgcca atcatgggca aaaggtaaaa tatcatcatg
     5041 ctttggtggg ctgcaactcc cgtttggata ccttgcaggc cgctgtctta gatgttaagc
     5101 ttcggtattt ggatgaattt gccgccgctc gttgtaaagt ggctgctaga tacgatgctg
     5161 ccttttccgg attggatgct gtacgcaaac cactaaaatc agccttttca tcgcatgttt
     5221 atcatcaata tacggtacag ctagctgtag aaaagaggga tcaagtacaa gctgcgttaa
     5281 aagaacgagg cattccttct atgatttatt atccattgcc tttgcaggag caagaggtga
     5341 tgaggggtcg atgccggatt tccggggatt tgaatgtcgc ttctcgcttg agccgatccg
     5401 tattatcctt gccgattcat acggagatga cagaagagga gcaggcctat attatagaat
     5461 ctataaagag tgttttatga ataagaagat acgtttcgcc gtgatcggct gtggtcatat
     5521 aggtaagcgt catgccgaga tgattacccg ggatgaagga gcggagttgg tcgctttatg
     5581 tgatatccgt ccgaaagagg agctggggat cgaggcttat gcggtccctt tcgcccggga
     5641 tatagatgaa ctattccgtt tgggattgga tatagatgtg gtgaatattt gtacacctaa
     5701 cggcttacat gccgagatgg cgatccaagc gatagagagc ggacatcatg tggtcataga
     5761 aaagcctatg gccttgacct tggcggatgc cgagaaagtg gtttatacct cgttgagatt
     5821 ccgtaagcag gtattttgcg taatgcaaaa ccgatattcc ccgccttcgg tctggatcaa
     5881 ggagatggtt gagtccggaa aattaggcca gatttatatg gtgcagctga attgctactg
     5941 gaaccgtga
//
LOCUS       DBMDTB010000156         5943 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_3364_length_5943_cov_8.222527, whole genome shotgun sequence.
ACCESSION   DBMDTB010000156 DBMDTB010000000
VERSION     DBMDTB010000156.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 5943)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 5943)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5943
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_3364_length_5943_cov_8.222527"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(69..2423)
                     /locus_tag="ACZPB4_16060"
     CDS             complement(69..2423)
                     /locus_tag="ACZPB4_16060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1099767.1"
                     /translation="MKTIIRNFINVLTRFKVATILNVAGLAVAFAAFIVILIQVNFEW
                     MFDRCHPTSDRIYRVELTPAVGLNTILSRGLVEAVIQSSPHIEAGTLLTPSFGEIYLT
                     TEKKDGERLGFEETITTCHPTLPSIFQFPLIEGDLNCLDEPEKVMIPESLAMRLFGKG
                     VSAVGKSLHAEQAVWTKSQTLFTIGAVYKDFPDNTQLKNVIYTSIDPDYEINNFDASN
                     WICYLLLDQSSSAGGVMDSFNRHFDFSKIGRPEVRVQLVPLTDIYYLDEPNNYSMSRK
                     GNLEVTVLLLGLAILIIFVAAINFTNFSTALTPLRVRSINTQKVLGSSYRILRGSLLI
                     EAVLISLIAWLIGLWIVWGLDRTVALPFLEADLDFSVNIPVIVVSGLIAMLTGIIAGL
                     YPSYYVTSFPPALVLKGSFGLSPVGRKLRMVLIGFQFVVSILLIILSCFMGIQSHYIR
                     NFSLGFDKDAIAIVELNPTLYDKHHTTYVDRLKGYPGIEDVAFSTAKVGAGDNYSYNT
                     VTYKDQEFTYFNIRVSSNFFQVMGISVAEGREFSKADEGSENVVYIFNRAAHIGANMK
                     EGDNFHDGRIIGFTDHVKFTSLRDGENNIAFSCMSSKKTMPVSYIRLKAGTDMFAAVD
                     YIRETLKGLDSAYPFDVEFYDEIFDNLYHKEDALRDMITVFGLLAIILSLVGVFGLVV
                     FDTQYRRKEIGIRKVHGATVGEILRMFNKSYVRIVIVCFVIAAPVAWLGVEKWLENFA
                     YKTPVYGWVFLLALVVVCFITLLTVSFQCWRAANANPVDSIKTE"
     gene            complement(2446..2526)
                     /locus_tag="ACZPB4_16065"
                     /pseudo
     CDS             complement(2446..2526)
                     /locus_tag="ACZPB4_16065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005777484.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(2527..4884)
                     /locus_tag="ACZPB4_16070"
     CDS             complement(2527..4884)
                     /locus_tag="ACZPB4_16070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1099768.1"
                     /translation="MKTILRNLLSVLRRFKMATLLNVLGLSVAFSAFILIMMQVDYDR
                     NFDRGIKDVDRIFRVEVAYESGTKQAIINRPLAEAFIRSSPHILAGSLLDPWGEGAFF
                     YTEENGVRNNFKERWMRVFPEYADIFTFDMLDGSADKLKEPNMVLLPLSLSSKLFGNQ
                     SAVGKQLHMANSKGVFTVGGVYRDFPDNSSVGNSIYYQLNPKENFQNFGNWNYMFYVR
                     LDDPANASGLFENFKAHFDVSTLSKDFSWEGGGMSLVLNPLTEVHFDSGVTYDNAPKA
                     SKSTMLVLFAIAIVIVVIAGINFTNFSTALTPMRIKSINTQKVLGGEVSVIRMSLILE
                     AIVISVISFLLALLWVSLFSSTTLSALIDARIALMDYPLLLGATALIAIATGLCAGLY
                     PAYYMTSFSPALVLKGSFGLSPKGRQMRNVLIGVQYVASFGLIIGAVFMYLQNYYMQH
                     APLGYDKDEIIVTDLNAKLWKSHEAFVSQVKSFSGIDDVTFAEPLLSSSDQYMGWGRE
                     YQGREISFQCLPVDPSFLKVLGIQVNEGRDFREEDANNPYGAYIFNERARAAYEMEVD
                     AMIDSAKIVGFIPDVKFASFRTEIAPMAFFVWGTRNWGSRPNWAYIKVKAGSDLRAAM
                     DHVRSAVRTFDPEYPFNIRFFNQVLNDLYKKEGNLSSLITLFGLCAIFISIVGVFGLV
                     VFDSEYRKKEIGVRKVLGSTTGEIIVMFNKTYIRILCICFVLGAPAAGYAVHRWLENF
                     AYKTPMYWWVYLIAFALVSIITILTVTFQNWHAANENPVHSIKNE"
     gene            complement(4910..>5943)
                     /locus_tag="ACZPB4_16075"
     CDS             complement(4910..>5943)
                     /locus_tag="ACZPB4_16075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1099769.1"
                     /translation="IVLLQYDRLMNNDLGYDPENIVYAPLNNMDDQKTAKLTAEFKKL
                     PYVMATGLSSMDILSGYGGFPILDNEKNWLFTARQVNYNADYLSLMKIPLLEGQPLKG
                     DGDILVNESFVSKRGWTDGAIGKYIYDDEGNLKGKIVGVTRDFMVNSFFTPQLPVIMF
                     GSDRMSYCNFTVRVSELTPEYLREMNDRIAELFPDEDVGFTVLKTIIESQYEGTRHFR
                     DGVFVASIAILLIILMGLLGYITDEMHRRSKEIAIRKVNGATAPNILRLLSKDVLVTA
                     FPAILLGVIASRVVGESWLRQFADKIPLTVFIFISTALLVLAIIWGCVILKSWNIANE
                     NPVRSIKNE"
BASE COUNT         1848 a         1528 c         1090 g         1477 t
ORIGIN      
        1 ttttaaaccg cctcaacaca cttagaaagt ttcgaataat cgttttcatt ttattatagt
       61 ttcatttatt attccgtttt aatactatcc accggattcg cgttcgccgc acgccaacat
      121 tggaaagaga cagtcaacaa tgtaataaag caaacgacga ctaaagccag taaaaacacc
      181 caaccataaa ccggtgtttt ataagcaaaa ttctccaacc atttctctac gccaagccaa
      241 gcaaccggag ccgcgatcac gaaacagact atcacgatcc tcacatacga tttattgaac
      301 atccgcaaga tctctcctac tgtagctcca tgtactttgc gaatacctat ttcctttctc
      361 ctatattgcg tatcaaatac gaccaagcca aataccccaa ccaatgaaag tataatagcc
      421 aaaagtccaa aaacagttat catatctcgt aaggcatctt ccttatgata tagattgtcg
      481 aatatctcat catagaactc tacatcaaaa gggtaagcag aatctagccc tttcaaggtc
      541 tctcggatat aatccacggc ggcgaacata tccgtacccg cttttaatcg aatgtaagaa
      601 acaggcatcg tttttttcga actcatgcaa gagaacgcga tattgttttc tccatcccgg
      661 agcgacgtga atttgacatg atccgtgaag cctataatac ggccatcgtg aaaattatct
      721 ccttctttca tattcgcgcc aatatgtgcc gcacggttaa atatgtaaac gacattttcc
      781 gatccttcat ctgcttttga gaattcgcgc ccctcggcca ctgatatccc catgacctga
      841 aagaaattag aagagaccct aatattgaaa taggtaaatt cttgatcttt ataagtcacg
      901 gtattataac tataattatc gcccgccccg actttcgccg tagagaaagc tacatcttca
      961 atgccgggat atcccttcaa acggtccaca taagttgtat gatgcttatc gtatagagtc
     1021 ggattcaact ccacgatcgc aatcgcgtcc ttatcaaaac ccaaagaaaa attccgaata
     1081 taatgacttt gaatccccat gaaacaagac agtataatca acaggataga tactacaaac
     1141 tggaaaccaa tcaaaaccat ccgtaatttc ctaccgactg gagaaagtcc aaaacttccc
     1201 ttcagaacca aagccggagg aaaagaggtc acataataag aaggatataa acctgcgatt
     1261 atacctgtca acatagcgat caatccagaa acaacaatta ccggaatatt aactgaaaaa
     1321 tccaaatccg cctcaagaaa aggtaaagct actgttcggt caagtcccca tactatccat
     1381 aaaccgatca accatgcaat aaggcttatc agaacagcct cgattagtaa agagcccctc
     1441 aagatacgat acgagctacc caaaaccttt tgggtattga tactacggac acgcaaaggc
     1501 gtcaacgccg tactgaaatt cgtaaaattt atagcggcta caaaaatgat caatatagct
     1561 aatcctaaaa gcaagacagt tacctcaaga ttccctttcc gagacatgct ataattgtta
     1621 ggttcatcca aataataaat atcggtaagc gggactaact gaacccgaac ctccggccgc
     1681 cctattttag agaaatcaaa atgccggtta aaactatcca tcactcctcc cgctgaagag
     1741 gattgatcca gcaatagata acagatccag ttacttgcgt cgaaattatt gatctcgtaa
     1801 tccggatcaa tcgacgtata gatcacattc tttagctgcg tattatccgg aaaatcttta
     1861 tataccgccc ctatcgtaaa aagagtttgc gatttcgtcc ataccgcttg ctccgcatgt
     1921 aatgatttac cgaccgctga aactcctttc ccgaaaagcc tcatcgccaa actttcaggg
     1981 atcataacct tttccggctc atccaagcaa ttaagatcac cttcgatgag tggaaattgg
     2041 aagatagaag gtaaagtcgg atgacaggtt gttatggtct cttcaaatcc caaccgttct
     2101 ccatcttttt tctcagttgt caaataaatc tccccgaaag aaggggttaa caatgttcca
     2161 gcctcaatat gtggagaaga ttggataact gcctcaacca atccgcggga taagatcgta
     2221 ttgagcccga ccgcaggtgt tagctctacc cgataaatac gatcggaagt cgggtggcaa
     2281 cgatcaaaca tccactcaaa atttacctgt atcaaaatca cgataaaagc agcgaaagcg
     2341 accgccaatc ccgctacatt caaaatggta gctaccttga aacgtgttaa tacattgatg
     2401 aaattacgta tgattgtttt catgacttac tctattttat tgttgcatga cctcggcacc
     2461 gttcttggaa tccaaattac ccgttggctc atcggccaag atcatcttag ggttggagac
     2521 taccgcctat tcattcttga tactatgtac cggattctcg ttcgccgcat gccagttctg
     2581 gaaggtgaca gtcaatatcg tgatgatcga gacaagagcg aaggctatca gataaaccca
     2641 ccaatacatc ggggtcttat aagcgaaatt ctctagccag cgatgcaccg catagcccgc
     2701 agccggagcg cccagcacaa agcagataca taaaatacgt atgtacgtct tgttgaacat
     2761 cacgataatc tcgcccgtgg tagagcccag caccttgcga acaccgatct ctttcttccg
     2821 gtactcgcta tcgaaaacca ccaagccaaa gacccctacg atagagatga aaatagcgca
     2881 tagcccgaac aaggtgatca aggaactcag attcccctct ttcttataca aatcattcaa
     2941 cacctgattg aaaaaacgga tattgaaggg atactccgga tcgaatgttc gcacggccga
     3001 tcgcacatga tccatggctg cccgcaagtc tgatcccgcc ttcaccttga tatatgccca
     3061 gttaggacga ctcccccaat tacgtgttcc ccatacgaaa aacgccatgg gcgctatctc
     3121 cgtacggaaa gaggcgaatt tcacgtccgg tatgaaaccg acgatctttg cgctgtcaat
     3181 catcgcatcc acctccattt cataggcggc acgcgcacgc tcattaaaaa tataagcccc
     3241 ataaggattg ttagcgtctt cctcccgaaa gtcgcggcct tcatttactt gtatccctag
     3301 cacctttaga aaagaaggat ctaccggcag gcattgaaaa ctgatctctc tgccttgata
     3361 ctcacgtccc caccccatgt actggtcact gctggagaga agaggctcgg cgaacgtcac
     3421 gtcatcgatg cccgagaaag atttcacctg gctcacgaaa gcctcatggc ttttccagag
     3481 tttagcgttc agatcggtaa cgataatctc atccttatca tagcctaacg gggcgtgctg
     3541 catataataa ttctgcaaat acatgaatac cgccccaata atcaacccaa atgaagccac
     3601 atactgcacg ccaatcaaga cattacgcat ctggcgacct tttggtgaca gaccgaaact
     3661 tcctttcaat accaaggccg gagaaaaaga tgtcatataa taagcgggat acaacccggc
     3721 gcacaaaccg gtagcaatcg caatcaatgc cgtagccccc aacaacaacg gataatccat
     3781 caaggcaatc cgagcgtcga taagcgcaga taaggttgtg ctggaaaaca aagagaccca
     3841 aagcaacgcc aacaggaaag agataacact gataacgata gcctccaaaa tcagagacat
     3901 acggatcacc gagacctcgc cacccaatac tttttgcgta tttatgctct tgatacgcat
     3961 gggtgtaagc gccgtactga agttcgtgaa attaataccg gcaatcacta cgatcacaat
     4021 ggcgatcgca aataagacaa gcatagtaga tttacttgcc ttcggagcat tatcgtaagt
     4081 gaccccggag tcgaaatgca cctccgtcag agggttcaag accaaagaca ttccacctcc
     4141 ttcccaagag aaatctttcg ataaggtaga tacatcgaaa tgcgccttga aattctcgaa
     4201 caagccggaa gcattcgccg gatcatccaa acggacgtag aacatataat tccaattgcc
     4261 aaagttctgg aaattctctt tcggatttaa ttggtaatag atgctattcc ccacggatga
     4321 gttatccggg aaatcccgat acactcctcc aacggtgaaa acacctttcg aattagccat
     4381 atgcaactgc ttacccaccg cggattgatt gccgaaaagc ttgctcgata gacttagcgg
     4441 aagtaatacc atattgggtt ctttcaattt atcggcactg ccgtccaaca tatcaaacgt
     4501 aaatatatcc gcatactcag gaaatacacg catccatcgc tccttgaaat tattccggac
     4561 accgttctcc tccgtataaa agaaagcgcc ctctccccaa ggatccaata acgaaccggc
     4621 cagaatatgc ggtgatgatc ggataaaagc ttccgccaac ggacgattta taatagcctg
     4681 tttcgtacca ctttcataag ccacctctac ccggaatatc cgatccacat cctttatgcc
     4741 tcggtcaaaa ttccggtcat agtccacttg catcattatc aggataaaag cggaaaaagc
     4801 cacagatagt cctaatacat ttaaaagtgt cgccatcttg aaacggcgca atacgctcaa
     4861 gagattcctc aaaatagtct tcatacgcaa ttttatatta cctattatat tattcgttct
     4921 taatgctacg gaccggattc tcattggcga tattccaaga tttcaggatc acgcatcccc
     4981 aaatgatagc tagaaccagt agagccgtag atatgaaaat aaaaacagtc agcggtatct
     5041 tatccgcgaa ttgcctcaac cagctctctc ccacgactcg tgaggcgatc actcctaaaa
     5101 ggatagccgg gaaagccgtg accaaaacgt ccttagataa aagacgtaaa atattcgggg
     5161 ccgtcgctcc attcaccttg cgaatcgcta tctccttgct cctacggtgc atctcgtccg
     5221 taatatatcc taataatccc attaagatga tcagcaagat agcgatcgag gcaacaaaga
     5281 caccgtcacg gaaatgacga gttccctcat actgagactc tataatcgtt ttcagcaccg
     5341 taaaaccgac atcctcatcc ggaaatagtt ccgcgatccg atcattcatt tcccgcaaat
     5401 attccggagt tagctcggag acacgaaccg taaagttaca ataactcatc cggtcactac
     5461 caaacatgat taccggtaac tggggagtga agaaggaatt caccatgaaa tcacgggtta
     5521 cacccactat ttttcccttt aaattgccct catcatcata aatatattta ccgatcgcac
     5581 catccgtcca cccacgttta ctcacgaatg actcattcac taagatatcc ccatcacctt
     5641 ttagtggttg cccctcaagc aaggggattt tcatcagaga gagataatcg gcgttatagt
     5701 ttacctgtcg ggccgtgaac agccagtttt tctcattatc cagaataggg aaaccaccat
     5761 aaccacttag aatgtccatg gacgaaagcc ccgtagccat gacataaggt aacttcttga
     5821 actcggcggt aagtttggcc gttttctgat catccatatt attcaagggg gcatacacta
     5881 tattttccgg atcatatcct aaatcattat tcattagccg atcatattgc aataacacga
     5941 tca
//
LOCUS       DBMDTB010000157         5909 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_3391_length_5909_cov_10.727789, whole genome shotgun sequence.
ACCESSION   DBMDTB010000157 DBMDTB010000000
VERSION     DBMDTB010000157.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 5909)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 5909)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5909
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_3391_length_5909_cov_10.727789"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..1005
                     /locus_tag="ACZPB4_16080"
     CDS             <1..1005
                     /locus_tag="ACZPB4_16080"
                     /EC_number="4.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014299506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016841 - ammonia-lyase activity [Evidence
                     IEA];
                     GO_process: GO:0170035 - L-amino acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAL/PAL/TAL family ammonia-lyase"
                     /protein_id="HIR1099770.1"
                     /translation="VYYKGRKREAISVLDEFAWKPVKLKSKEGLALLNGTQFMSANGV
                     FALMRAFSLSKKADLIAALSLEAFDGRIDPFMDCIQQMRPHPGQIETGAAFRRLLEGS
                     ELIARKKEHVQDPYSFRCIPQVHGATKDAINYVANVLLTEVNSVTDNPTIFPEEDKII
                     SGGNFHGQPLAISYDFLAISLAELGNISERRVAQLIMGLRGLPEFLVANPGLNSGFMI
                     PQYAAASMVSQNKMYCYAASSDSIVSSNGQEDHVSMGANAATKLFKIMDNLDHILAIE
                     LMNAAQGIEFRRPARTSPVLEKFLKDYRKEVPFIDEDIIMYTEIHRTVAFIRRKDFVY
                     "
     gene            1105..2259
                     /locus_tag="ACZPB4_16085"
     CDS             1105..2259
                     /locus_tag="ACZPB4_16085"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016413 - O-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HIR1099771.1"
                     /translation="MQNVTNPTVKTHVVWLDVVRLIAMFTVVCCHCTDPFNFYPGDSP
                     IIGDIKFWGAAYGAFLRPCVPLFVMITGALLLPVREETSIFYKKRILRVFWPFLIWSV
                     IYNLFPWFTGLLGLRPELILDFFPYSGEEVTRQSLSVSLGYIAQIPFNFSLLDVHMWY
                     IYLLIGLYLYLPIFSAWVEKVSDKAKLWFLAGWGVTLFIPYYREFVSPYIWGGCSWNE
                     FSMLYYFAGFNGYLLLGHYLRNHDWSLGKIVGIGIPMFVVGYAITFFGFRYTTALPAY
                     TEEQLELFFYYCSPNVVMMTIPIFLLAKKVNVKSDTIKRMLANLTICGFGIYMVHYFF
                     TGPSVLLARALNIPLGLQIPAASVVAFAVSWLIVLGIRKICGKKAKYIVG"
     gene            complement(2380..3489)
                     /locus_tag="ACZPB4_16090"
     CDS             complement(2380..3489)
                     /locus_tag="ACZPB4_16090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0140663 - ATP-dependent FeS chaperone
                     activity [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Mrp/NBP35 family ATP-binding protein"
                     /protein_id="HIR1099772.1"
                     /translation="MTIYPNLIIEALKNVRYPGTGKDIVSMGLVEDNIRIDGMNVTFS
                     LLFEKPNDPFIRSVVKAAETAILTYVSPEVNIKGNITVKARQLARPEPDKLLPQVKNI
                     IAVSSGKGGVGKSTVAANLAVALALQGYKVGLLDADIFGPSQPKMFNLEEARPYMEEV
                     EGRELIKPAENYGVKMLSIGFFVNKNDAVLWRGAMASNALKQLIGDANWGELDYFLID
                     LPPGTSDIHLTMVQTLAITGAVVVSTPQEVALADARKGISMFTGDKVNVPVLGLIENM
                     AWFTPAELPENKYYIFGKEGCKRLAEELNVPLLGQIPIVQSICEGGDQGKPVALNPDS
                     ITGKAFQELAENVVKQIDYRNEHLAPTERVIVTKK"
     gene            complement(3516..4274)
                     /gene="trmB"
                     /locus_tag="ACZPB4_16095"
     CDS             complement(3516..4274)
                     /gene="trmB"
                     /locus_tag="ACZPB4_16095"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005679168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008176 - tRNA
                     (guanine(46)-N7)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HIR1099773.1"
                     /translation="MGKNKLAKFDDMAGYPHVFQYPFAALQEKGFDMKGQWHERFFKN
                     DHPIVLELGCGKGEYTVGLGKLFPNKNFIGVDIKGARMWTGAKESLEAGMNNVAFLRT
                     SIELISYFFAPGEVAEIWITFPDPQMKKVNKRLTGTRFMKMYREILSGDGIIHLKTDS
                     NFMYTYTCEMVKTNHYPVLFSTDDLYHSNLADEILSIKTYYEQQWLDRGLNIKYIKFV
                     CEERERLVEPDVEIELDPYRSFNRSKRSALASGK"
     gene            4420..>5909
                     /locus_tag="ACZPB4_16100"
     CDS             4420..>5909
                     /locus_tag="ACZPB4_16100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012056122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016758 - hexosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase 87 family protein"
                     /protein_id="HIR1099774.1"
                     /translation="MLRVFFRRPIFKNPRFVGFVWFATALVACLLKLPVGRTYNNFMI
                     YRASFFHALELKDLYIYYPNEYHDRFLYGIPFTAIIVPFSLFSPYIGMLLWCLANSLL
                     LYMAIRKLGLADWKQAFVIWVCLNELFTCVLMQQFNIAIAGMILFSFIFIERKQEFWA
                     ALMIVLGTMTKIYGIVGLAFLLFSKRRIAFLKGLIFWGIVLYVLPMLYTSPQYVASQY
                     VKWYEVLLDKNVENLFTPYTNISLLGMVRKISGVNTYSDLWLVIPGLLLFIAPYFRIN
                     QYDNRRFRMHFLCSTLLFMVLFSSGTENSGYLGAMIAVCLWYIGTPTRKTTPVLNTVL
                     FVFCFILTSLSPTDIFPCYIRKTYVIPYALKALPCVLIWFKIVWEQLTLDFSEPLHRP
                     KTLPGKEEAIDLILPCYNPQEGWVRLMIEKHAELVKMLKGRSLRFIVVNDASRRGFTK
                     DAVGRLLEALPDTMIVSYDTNKGKGAAVRAGLSHSTSSITLYTDYD"
BASE COUNT         1415 a         1222 c         1360 g         1912 t
ORIGIN      
        1 gtttattata agggccgcaa acgggaagcg atcagcgtat tggacgagtt cgcttggaag
       61 cctgtgaagc tgaaaagcaa ggaggggtta gctttattga acggtacgca atttatgagc
      121 gccaatggcg tattcgcctt gatgcgtgcg tttagcctgt ccaagaaagc ggatctgatc
      181 gccgctttat ctttggaggc tttcgatggg cgtatcgatc ctttcatgga ttgtatccag
      241 cagatgcgtc cgcatcccgg acaaatcgag accggggccg cttttcgacg gctattggag
      301 ggaagtgagt taatcgcccg gaaaaaggaa catgttcagg acccgtattc attccgttgt
      361 atccctcaag tgcatggggc tacgaaggac gctatcaatt atgtggcgaa tgtcctgctt
      421 accgaagtaa attccgtgac ggataacccg acgatcttcc cggaagagga taagattatt
      481 tccggcggta atttccatgg tcagcccttg gcgatttctt atgatttctt ggcgatttcc
      541 ttggctgagt taggaaatat atcggaacgt cgtgtcgctc aattaatcat gggtttgcgg
      601 ggattgcctg agttcttggt cgctaatccc ggcctgaact ccggtttcat gatccctcaa
      661 tatgcggctg ccagtatggt aagccagaat aagatgtatt gctatgcggc gagcagcgat
      721 tctatcgtgt ccagtaatgg gcaagaggat catgtgagta tgggagcgaa tgcggcgacg
      781 aagttgttta agatcatgga caacttggat catatcttgg cgatcgagtt gatgaacgcc
      841 gcacaaggaa tcgagttccg tcgtccggct aggacttccc cggtattaga gaagttcttg
      901 aaggattacc ggaaagaggt gccatttatc gacgaggata ttatcatgta cacggaaata
      961 catcgtacgg tggcgtttat tcgtaggaaa gactttgtat attaatgaat atcgttaata
     1021 gaggttagaa atccagctga atctcctatt cggctggatt attttgtatt ttcgccgtca
     1081 atctaaacac aatcgatcta ctttatgcaa aatgtaacaa atcctaccgt gaaaacacac
     1141 gtagtttggc tggatgtcgt acgcttgata gccatgttta ctgttgtttg ctgtcattgt
     1201 acagacccgt ttaatttcta tcccggagat tctccgatta ttggggatat taagttttgg
     1261 ggagctgcct atggggcttt tcttcgtcct tgtgtacctc tgttcgttat gattacggga
     1321 gccttgttgc taccggtccg ggaagagact tctattttct ataagaaaag gatattgcgt
     1381 gtattctggc ctttcttgat ttggtctgtt atttataatt tatttccttg gtttacggga
     1441 ctgcttggtt tgaggccgga acttattctt gatttcttcc cttattcggg agaagaggtg
     1501 actcgtcaat cgttgagtgt gtctttaggc tatatcgccc agataccgtt caatttctca
     1561 ttgttggatg tacatatgtg gtatatctat ttactgatag gtttatatct ttatttgccg
     1621 atcttctccg cttgggtcga gaaagtttcg gataaggcga aattatggtt tctggcaggt
     1681 tggggagtga ctttgtttat tccttattat cgggaattcg tatctcctta catttggggt
     1741 ggatgctcat ggaatgaatt cagtatgctt tattatttcg ccgggtttaa cggttacttg
     1801 ctattggggc attatctgcg gaatcatgat tggtcgttag gaaagatcgt tgggataggc
     1861 attcctatgt ttgtcgtagg ctatgccatt actttcttcg gtttccgcta tacgaccgct
     1921 ttgcctgctt acacggagga acagttagag ttattcttct attattgttc tcccaatgtg
     1981 gtgatgatga cgattcctat cttcttgctg gcgaagaagg taaatgttaa gtcggatacg
     2041 attaagcgaa tgttggcgaa cttaaccata tgcggtttcg gtatctatat ggtacattat
     2101 ttctttacgg gacccagcgt gctgctggcg agagccttga atatcccttt gggtttacag
     2161 attcctgccg cttctgtggt agcattcgct gtatcttggc tgatagtgtt gggtatcaga
     2221 aagatttgcg gtaagaaagc caagtatatt gtgggctgaa tttatacgta cgttcgcata
     2281 ggctgatacg tatataggcg taggcccatg cgagcgtacg tgtaggacga tacgtatata
     2341 cgtgcgagac cacacgtata tacgtaatat aaatcatctt tatttcttgg ttacaatcac
     2401 tcgctctgtc ggagccagat gctcgttgcg atagtctatc tgcttgacta cattctcggc
     2461 caattcttgg aatgccttac ctgtgatcga gtccgggttc aacgctaccg gcttaccttg
     2521 atctcctcct tcgcagatac tttgtacgat aggaatctgt cccagtaacg gcacgttcag
     2581 ttcttcagct aggcgtttac aaccttcctt tccgaatata taatatttgt tttccggtaa
     2641 ttccgcaggg gtaaaccaag ccatattctc gatcaatcct aaaacaggga cattaacctt
     2701 atccccagtg aacatgctga tacccttacg agcgtccgct aaagcaacct cttgcggcgt
     2761 acttaccacc acggctccgg ttatcgctag tgtttgcacc attgtcaaat ggatatcact
     2821 cgttccggga ggtaaatcaa ttaagaaata atcaagctca ccccagttgg cgtcgccgat
     2881 caattgcttc aatgcgttgc tagccattgc tccacgccat aggactgcgt cgtttttatt
     2941 aacgaagaag ccgatggata acatcttgac accataattt tcggccggct tgatcagttc
     3001 cctgccctct acctcttcca tataagggcg agcctcttct aggttgaaca tcttgggttg
     3061 ggacggcccg aatatatcgg catccagcaa tcctacctta tatccttgta aagccaatgc
     3121 gacagctaga ttagcggcaa cggtactttt accaactcct cctttaccgg aagatacggc
     3181 gataatattt tttacttgcg gtaataattt atccggttcc gggcgagcta actgacgggc
     3241 ttttaccgtg atgtttccct tgatattcac ctccgggctt acataggtta agatagctgt
     3301 ctccgcggct tttactacgg agcggataaa cggatcattc ggcttctcga ataataacga
     3361 gaaggtgaca ttcataccat cgatacgaat gttgtcttct acgaggccca tggaaacgat
     3421 gtcctttccg gtacccgggt aacgaacgtt cttcaacgcc tcaataatca gattcggata
     3481 gattgtcata tctgttgatt tttttagtca ttcttttatt taccagaagc caaagcgctt
     3541 cgtttactgc gattaaagct acgataagga tctaactcta tttctacgtc aggttccacc
     3601 aatcgttccc tttcctcaca aacaaacttg atgtatttga tgtttaatcc acgatccagc
     3661 cattgttgct cgtaataggt cttgatggat aagatctcat ccgccagatt ggaatgatat
     3721 aggtcgtctg tactgaacaa tacgggataa tggttcgttt ttaccatctc gcacgtatag
     3781 gtatacatga agttactgtc cgtttttaaa tggataatac catctccgga aaggatttcc
     3841 cgatacattt tcatgaagcg ggttccggtc agacgcttat tgaccttttt catttgaggg
     3901 tccggaaatg tgatccagat ctcggctact tcgcccggag cgaagaaata ggaaatcaat
     3961 tcgatactgg tacgtaggaa agccacgtta ttcatcccgg cttccagcga ttctttcgct
     4021 ccggtccaca tacgtgctcc cttgatatcg acaccaataa aattcttatt tgggaaaagc
     4081 tttcccaaac ctacggtata ttcccctttt ccacatccca attccaagac aataggatgg
     4141 tcgttcttga aaaaacgttc atgccactgt cctttcatat caaacccttt ttcttgtagg
     4201 gcggcgaaag ggtattggaa tacgtgcgga tagcccgcca tatcgtcaaa cttagctaat
     4261 ttattctttc ccatgtcgcg aagataatac ttaaaaaaat gctttttacg ttttttctac
     4321 tgttttagat aggggttttt atacgttggc gagtcttttg aacatatagg ctgtcagaag
     4381 ttttatttga aagtggagtt gtaacgaata aaaaaggata tgttgagagt attttttaga
     4441 cgcccgatat ttaagaatcc gaggtttgtc ggatttgttt ggtttgcgac ggcccttgtc
     4501 gcttgcttat tgaaattacc tgtgggaagg acttataata actttatgat ttatagggct
     4561 tcctttttcc atgcgttaga gttgaaagac ctttatatat attatccgaa tgaataccac
     4621 gaccggtttt tatacgggat cccttttacg gctataatag tgcctttctc cctcttctct
     4681 ccttatatcg gaatgttgct atggtgtctc gcgaatagct tgctgcttta tatggctatc
     4741 cgtaaactcg gattggcgga ttggaaacag gcgtttgtca tttgggtatg cttgaatgag
     4801 ttatttacgt gtgttcttat gcagcaattt aacatagcca tagccggcat gattttattc
     4861 tcgtttattt ttattgagcg gaaacaggag ttttgggcgg cgctaatgat tgtcttgggt
     4921 acgatgacta agatttatgg cattgtcggt cttgctttcc tgctattctc aaaacgccgg
     4981 atcgcctttt tgaaaggact tattttctgg ggcatagtct tgtatgttct tccgatgtta
     5041 tatacgtctc ctcaatatgt ggcaagtcaa tacgtgaaat ggtatgaggt acttctcgat
     5101 aagaatgtag agaatttatt tactccttat acaaatatct ctttgttggg gatggttcgt
     5161 aagatttcgg gagtcaatac gtatagtgat ctctggttgg ttatccccgg gctactttta
     5221 tttattgctc cttattttag gataaatcaa tatgataacc ggcggttccg catgcatttt
     5281 ctttgctcta ctcttttgtt catggttctt tttagctccg gaacagagaa tagcggatat
     5341 ttgggagcca tgatagccgt ctgcctttgg tatataggta cgcctacccg taagacgact
     5401 cctgtcttga atacggtact attcgttttc tgttttattc ttacatccct ttctccaaca
     5461 gatatatttc cctgttatat ccggaaaacg tatgttattc cttatgcgtt gaaagcacta
     5521 ccttgtgtgt tgatctggtt taagatcgta tgggagcaat tgacattgga tttttcagag
     5581 ccgcttcatc ggccgaagac tctcccgggt aaagaggagg cgatcgacct tatcttgcct
     5641 tgttataacc cacaagaagg ctgggtacgt ttgatgatcg agaaacatgc ggaattggta
     5701 aagatgctta aaggtcgctc acttcgtttt atcgtcgtga atgacgcttc gaggagagga
     5761 tttacgaagg atgcggtagg acgtcttctg gaggctctcc ctgatacgat gatcgtaagt
     5821 tatgatacga ataagggaaa aggagccgct gttagggctg gcttgtctca ttccacctca
     5881 tccattactt tatatacgga ttatgattt
//
LOCUS       DBMDTB010000158         5689 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_3509_length_5689_cov_10.754295, whole genome shotgun sequence.
ACCESSION   DBMDTB010000158 DBMDTB010000000
VERSION     DBMDTB010000158.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 5689)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 5689)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5689
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_3509_length_5689_cov_10.754295"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..114
                     /locus_tag="ACZPB4_16105"
     CDS             <1..114
                     /locus_tag="ACZPB4_16105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HIR1099775.1"
                     /translation="ALVHACAVEGDMRIVKRMKEIVPEFKSQHSKYEVLDK"
     gene            259..3558
                     /locus_tag="ACZPB4_16110"
     CDS             259..3558
                     /locus_tag="ACZPB4_16110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AsmA-like C-terminal region-containing protein"
                     /protein_id="HIR1099776.1"
                     /translation="MSMVRIRKILLVVVSVLVGIFFILPLIGVGILKWAVLPPEKLTP
                     LVVEKTNEFIEAHLECERVELTYFETYPYLGVKLTNGRLISHLAEDSIGYQEDLMIPS
                     DSLLSFKKAIVVFNPTDYLFSGKVTIPRVIMDSIRFYGYVNEEGKANWEIYQSEMDSV
                     DESSSSPLPKIDLQQVHITNGHFVYDDRQQDLYTAIDGFFLHIDGLLTQRGNKLDVET
                     GSSSIVFRSPSYSLANKLALRFKGRLLLADGLRRIGLRDAELLVNNLPFTADGFMVPA
                     TEDNPSRIDMTFGLKVSDMNDLLHFIPDEYFKDRDKTLAEGRIILEGDIRGELGDSIV
                     PTVNLCCKIEDGSYHVKGIEQGIDTLRMDVDLHLNGAYPDSSYVSLEELTLIGLNTSL
                     TMSGEVRDIWRNPAIRAEMKGQVDFTRLAKEFLNPDTLLLEGTMMADLSTVFKVDDIV
                     NSRFAKVKSSGNLTVDRFKAFSKPLGVDMYIAGANLFVGSTENESKYLNAKGLLSANL
                     SVDTLNIKYKDEISTNIGGLKMVANTTPVIDTTAVIPMTAGLEFDHLRTKLPDSTWMV
                     AGKTVLKGGIKASSTDKRIPMAGATISVDTLKYILIPLRTGMVLTESQFSLEALPYRQ
                     AIRQQRERRIAAGDTLRRRTQTTRRANRQRSQVDSVASSNSVLRQWEARGQVRFKQLR
                     GFSRLFPIPMYIDETSVKFNTNNMTLSGARLHLGKSDLTLSGELSDIRRAMLRGGKLK
                     ANFELESDLIDCNQLMLAIGKGLQFSDQLASNSVGAFSEDSISVLETDHLLANTVDSV
                     ATDSISQLFVVPKFLDLTLHTNAKKIDFKDLKLEDVKGEVVIRDQSINLSDLCMSSNI
                     GSGDLTMVYTTKTDQEATMGFELSLNDILVERLISLFPDIDTLVPMLRSFEGMVDCQM
                     TATCKADSTMSVLLPSVNASCYLSGKNMVLLDGETFTEISKTLMFKNKKRNMIDSIAV
                     DLAIHDNKIEVFPFLVEMDRYKVAVGGTHNLDMTFDYHLSVLKSPVPFKLGIDIKGNL
                     DDFKFKIVKCKYKDFLKPAKQAELDSTRRNVREEIRETIRKQIREAAPELGNSLSEIH
                     PHTHGHVEEST"
     gene            complement(3550..4689)
                     /gene="rfbB"
                     /locus_tag="ACZPB4_16115"
     CDS             complement(3550..4689)
                     /gene="rfbB"
                     /locus_tag="ACZPB4_16115"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007846915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HIR1099777.1"
                     /translation="MKTYLVTGAAGFIGANFIKHMLAKYDDIKIVVLDLLTYAGNLGT
                     IAEDIDGVRCEFVKGDICDRALADQLFEKYNFDYVVNFAAESHVDRSIENPQLFLQTN
                     ILGTQNLLDAARKAWVTGKAETGYPVWREGVRFHQVSTDEVYGSLGAEGYFHETTPLD
                     PRSPYSASKTSADLFVKAYHETYKMPVSITRCSNNYGPYHFPEKLIPLIIKNILEGKS
                     LPVYGDGTNVRDWLYVEDHCKAIDAVIHHGRVGEVYNVGGHNEKQNIEIVKLTIRTIH
                     QLMTEQPEYRQVLKKKEIGADGEISIDWINDNLITFVKDRLGHDQRYAIDPTKITNEL
                     GWTPETCFEVGIVKTIRWYLENQKWVEDITGGDYMKYYEQMYGSR"
     gene            complement(4703..5260)
                     /gene="rfbC"
                     /locus_tag="ACZPB4_16120"
     CDS             complement(4703..5260)
                     /gene="rfbC"
                     /locus_tag="ACZPB4_16120"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008830 - dTDP-4-dehydrorhamnose
                     3,5-epimerase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HIR1099778.1"
                     /translation="MTYTETVIPGVWIIEPKVLKDARGYFMEAFKQAEFEEHIGKIEF
                     VQDNESCSSKGVLRGLHYQLAPYSQSKLVRVIKGRVLDVAVDIREGSPTFGKYVAVEL
                     SDENKRQLFIPQGFAHGFHVLSDEAIFTYKVDNPYTPTHERGIRYDDPTVHVDWSITD
                     PESINLSEKDTKAPSLKDAELNFKY"
     gene            5426..5497
                     /locus_tag="ACZPB4_16125"
     tRNA            5426..5497
                     /locus_tag="ACZPB4_16125"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5459..5461,aa:Cys,seq:gca)
     gene            5557..5628
                     /locus_tag="ACZPB4_16130"
     tRNA            5557..5628
                     /locus_tag="ACZPB4_16130"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5590..5592,aa:Cys,seq:gca)
BASE COUNT         1437 a         1102 c         1469 g         1681 t
ORIGIN      
        1 gccttggtac atgcttgtgc cgtggagggg gatatgcgga tcgtgaagcg gatgaaggag
       61 atcgttcctg agttcaagag ccagcattct aaatatgagg ttctggataa atgaattgta
      121 gaaaaataaa taagatgtag aaagaaggtc tctcattgcg gggggccttt ttttatgaga
      181 taagcgttgt ctttgggata gtatttcgta tttttgctca tacaatttaa ttagtgttgt
      241 ttgtgataag atgaaggaat gagtatggta cgaataagaa agatattgct ggttgttgtg
      301 tctgtgttgg tcgggatctt tttcatactt cccttgatcg gggttggtat actgaaatgg
      361 gcggtcttac ctccggagaa gctgacaccg ctggtcgtag aaaaaacaaa cgaattcata
      421 gaggcgcact tggaatgtga gcgggtggag ttgacttatt tcgagacgta tccttatctg
      481 ggagtgaagt tgacgaatgg gcgtttgatc tcacatctgg ctgaggattc tataggctat
      541 caagaggatt tgatgattcc ttcggattct ttgctgtctt tcaaaaaagc gatcgtcgta
      601 tttaacccta cggattatct gtttagcggg aaagtgacga ttcctcgggt tatcatggat
      661 agtatccgtt tttatggtta tgtgaatgag gagggaaagg cgaattggga gatttatcaa
      721 agtgagatgg attcggtaga cgaatcatcg tcatctccat tgcctaaaat agatttgcag
      781 caagtgcata ttacgaatgg gcactttgtc tatgatgacc gccagcagga tttatatacg
      841 gcgatcgatg gtttcttttt acatatagat ggccttttga cccaacgagg aaataagttg
      901 gatgtggaga ccggttcttc ctcgatcgta ttccgtagcc cgtcttattc tttggcgaat
      961 aagttagcgt tacgcttcaa gggacgtttg ttgttggctg atggacttcg ccggattggg
     1021 ttgagggacg cggagttgct ggtgaataat ctgcctttta cggcggatgg ctttatggtg
     1081 ccggctaccg aggataatcc gtcacggatc gatatgactt tcgggttgaa ggtttccgat
     1141 atgaatgatc tcttacattt tattccggat gaatatttta aggatcggga taaaacactt
     1201 gctgagggac gtattatttt ggaaggggat atccgtggag aattagggga tagtattgtt
     1261 ccgaccgtga acttatgctg caagatagag gatggttctt atcatgtaaa aggtattgaa
     1321 caggggatcg atacattgcg catggacgtg gatttacatt tgaatggcgc ttacccggat
     1381 tcttcttatg tctctttgga ggagctgaca ttgatcgggt tgaatacctc gctgaccatg
     1441 agtggcgagg ttagggatat ctggaggaat cccgcgattc gggcggagat gaaagggcag
     1501 gtcgatttta cccgtttggc taaagagttc ttgaatcccg acacactgct gctggagggt
     1561 accatgatgg ctgatttatc tacggtgttt aaggtggatg atatcgtgaa tagccgcttc
     1621 gccaaggtca aatcatccgg caatttgacg gttgatcgct tcaaggcgtt tagtaagccg
     1681 ttaggcgtgg atatgtatat cgctggggcg aatctgtttg taggatctac ggaaaatgaa
     1741 agtaaatatc tgaatgcgaa aggattgttg agcgctaatc tatcggtgga taccttgaat
     1801 ataaagtata aggatgagat cagtacgaat atcggtggat tgaagatggt agccaatacg
     1861 acgccggtta ttgatacaac ggctgttatc cctatgaccg cagggttgga atttgatcat
     1921 ttacgcacca agttgccgga ttctacctgg atggtggccg gtaagaccgt gttgaaaggg
     1981 ggcatcaagg cttcttctac agataagcgg atccctatgg cgggagctac gatctcggtg
     2041 gacaccttaa aatatattct tatcccttta cggacgggta tggttctgac ggaaagccag
     2101 ttctctttgg aagcattacc ttatcggcaa gcgatccgtc aacaacgtga acgccgtatt
     2161 gccgccggtg ataccttgcg caggcgcacg cagaccaccc gaagggcgaa tagacagcgg
     2221 tcgcaagtgg attcggtcgc ttcctcaaac agtgtcttac gccaatggga ggctcgggga
     2281 caagtgaggt ttaagcaatt gaggggcttt agccgcttat tccccattcc gatgtatatt
     2341 gatgagacaa gcgtgaaatt caatactaac aatatgacgt tgagtggtgc ccgcctgcat
     2401 ttaggaaaga gcgatcttac tttgagcgga gagcttagcg acatccggcg ggccatgcta
     2461 cggggaggaa agctgaaagc gaatttcgag ttggaatccg atctgatcga ttgtaaccag
     2521 ttgatgctag ctataggtaa aggtttgcag ttttctgatc aattggcatc caattcagtt
     2581 ggggccttct cggaagacag tatctccgta ctggagacgg atcatctatt agcgaatacc
     2641 gtggatagtg tcgctacgga ttcgatctct caactatttg tcgttccgaa attcttggat
     2701 ctgacgcttc atacaaatgc taaaaaaata gattttaagg atctgaagtt ggaggatgtg
     2761 aaaggtgagg ttgtaatccg ggatcaaagt atcaatctga gcgatttatg tatgagctcg
     2821 aatatcggtt ccggagatct gacgatggtt tatacgacca aaacagatca agaggcgact
     2881 atgggatttg agttgtcctt aaatgatatt ttagtggaac ggttaatcag tttgttcccg
     2941 gatatcgaca cattggtccc tatgcttcgt tcgttcgaag gcatggtaga ttgccagatg
     3001 acggcgactt gcaaggcgga ttctacgatg tccgtgttgc tgccgtctgt aaatgcctct
     3061 tgctacctga gcggaaagaa tatggtgctg ctggatggtg agacatttac cgagatatcg
     3121 aagacgttga tgttcaagaa taaaaaacgg aatatgattg atagtatagc ggtagattta
     3181 gcgatccatg ataacaagat cgaggtattc ccattcttgg tggagatgga ccggtataaa
     3241 gtagccgtag gggggacgca taatttggat atgacgttcg attaccatct ctcggtttta
     3301 aaatcgccgg taccgtttaa gttgggtatc gatataaaag ggaatctgga tgatttcaag
     3361 ttcaagatag tgaaatgtaa atataaagat ttcttgaaac ctgccaagca agcggaactg
     3421 gatagtaccc gcaggaatgt gcgtgaggag atacgcgaga cgatccggaa acaaataaga
     3481 gaggccgctc ccgaattagg aaacagcctc tctgagattc atccacatac acacggtcac
     3541 gttgaggaat caacgtgatc catacatttg ctcgtaatat ttcatgtaat ctccaccggt
     3601 gatatcctct acccattttt ggttctcaag ataccaacgg atggttttta cgataccgac
     3661 ctcgaagcag gtctctggtg tccagcctaa ttcgttggtg atcttcgtcg ggtcgatggc
     3721 gtatcgttga tcatggccca gacggtcttt cacgaatgta atcaagttgt cgttgatcca
     3781 gtcgatagag atttctccat cggcaccgat ctcttttttc tttaatactt ggcgatattc
     3841 cggttgttcg gtcattagtt gatggatcgt ccggatcgtg agttttacga tctcgatgtt
     3901 ctgcttctcg ttatgaccgc ctacgttgta aacctctccc acacgtccgt ggtggattac
     3961 ggcgtcgatc gccttgcagt gatcctctac atataaccag tcgcgtacgt ttgtgccgtc
     4021 accatataca ggtagggatt taccttccaa tatgttcttt atgattaagg gaatcaattt
     4081 ttccgggaaa tggtaaggtc cgtagttgtt ggaacaacgg gtaatagata ccggcatctt
     4141 atatgtctcg tgataagcct ttacgaataa gtctgcgctt gtcttggagg cgctgtacgg
     4201 gctccgggga tctaaaggcg tggtctcgtg gaaataccct tcggcaccta ggcttccata
     4261 gacctcgtcg gtagagactt gatggaaacg tacgccttca cgccatactg gataacctgt
     4321 ctcggcctta ccggtaaccc atgcttttcg tgcggcgtcc aataggtttt gtgtaccaag
     4381 gatgttggtt tgcaggaata gctggggatt ttcgatgctt cggtctacat gactttcagc
     4441 ggcgaagttc acgacataat cgaagttgta tttctcgaat agctggtcgg ccaaggcacg
     4501 gtcgcaaata tcgcctttca cgaactcgca acgtactcca tcgatatcct cggcgatggt
     4561 gcccaaatta cctgcgtaag tcagcaagtc taggacaacg atcttgatat cgtcatattt
     4621 cgccagcata tgtttgataa aattggcacc gataaaaccg gcggcaccgg taactaggta
     4681 agttttcata tctgtacagt gtttagtatt tgaaattaag ctcagcgtct ttcagcgatg
     4741 gagccttggt gtctttctcg gataggttga tcgattccgg atctgtgatg ctccaatcta
     4801 catggaccgt gggatcgtca tagcggattc cccgttcatg cgtcggagta tatggattat
     4861 ctactttata ggtaaagata gcctcgtcgc ttaatacatg gaatccgtgg gcgaatccct
     4921 gtggaatgaa taactggcgt ttattctcgt ccgataactc tacagctaca tatttgccga
     4981 atgtgggcga gccttcacgt atatctacgg ctacatccaa tacccgtcct ttgatcaccc
     5041 tgactaattt agattgagaa tagggcgcta gctgatagtg taatcctcgt aatacgcctt
     5101 tagaggagca agattcgttg tcttgcacga actcgatttt tccgatatgc tcctcgaatt
     5161 ccgcttgctt aaaagcttcc ataaagtatc cgcgcgcatc tttcaatacc tttggctcaa
     5221 tgatccatac gcccggtatt acagtttctg tataagtcat tttttcgtta tttatctatt
     5281 tgataggcaa aggtaagctc attttctcta cttctataat attcggaggg aaaaataaaa
     5341 aagaaaggaa aagtttggta attccaatat tattctcttt ctttgcactc gcaaaacgaa
     5401 agtagttgtt ttgtgttgaa attatggttc cttggatgag tggcttagtc agcggtctgc
     5461 aaaaccgtgt acggcggttc gaatccgcca ggaacctctt ggtaattgag aattcagtat
     5521 taagaattga aaattacttt tatttttgat tgattcggtt ccttggatga gtggcttagt
     5581 cagtggtctg caaaaccatg tacggcggtt cgaatccgcc aggaacctcg gaggaaagcc
     5641 tcgaagttgt ttgtaatgaa cgcttcgagg ctttttttgt tttgtccgt
//
LOCUS       DBMDTB010000159         5500 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_3636_length_5500_cov_12.841452, whole genome shotgun sequence.
ACCESSION   DBMDTB010000159 DBMDTB010000000
VERSION     DBMDTB010000159.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 5500)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 5500)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5500
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_3636_length_5500_cov_12.841452"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            86..2089
                     /locus_tag="ACZPB4_16135"
     CDS             86..2089
                     /locus_tag="ACZPB4_16135"
                     /EC_number="4.2.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012056119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016153 - urocanate hydratase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="urocanate hydratase"
                     /protein_id="HIR1099779.1"
                     /translation="MEIHLDNYLPEYPSFVSGIRRAPDRGYSLTPAQTETALMNALRY
                     IPVELHEKLAPEFMEELLTRGRIYGYRYRPQGDLKAKPISEYKGKCIEGKAFQVMIDN
                     NLCFDIALYPYELVTYGETGQVCQNWMQYRLIKKYLEELTEEQTLVIESGHPLGLFHS
                     KPDAPRVIITNSMMVGMFDNQKDWHIAAQMGVANYGQMTAGGWMYIGPQGIVHGTFNT
                     LLNAGRKKLGIPQDKDLRGYLFVSSGLGGMSGAQPKAAVIAGAASIIAEVDASRIETR
                     RCQGWVQHVTDDMGKAFSLANEAIRKKEPISIAFHGNIVDLLEYADKQGLSIDLLSDQ
                     TSCHAVYEGGYCPVGVTFEERTELLAHHREDFCALVDKTLKRHFEVIKRLVARGTYFF
                     DYGNSFMKAIYDAGVHEISRNGVDEKDGFIWPSYVEDIMGPELFDYGYGPFRWVCLSG
                     KPEDLIRTDHAAMACIDPTRRGQDMDNYNWIRDAEKNRLVVGTQARILYQDAEGRLKI
                     ALEFNRMVRDGEVGPIMLGRDHHDVSGTDSPFRETSNIRDGSNVMADMAVQCFAGNAA
                     RGMSLVALHNGGGVGIGKAINGGFGMVLDGSERVDEILRSAMIWDVMGGVARRSWARN
                     PNAMRTSATFNENRGEQYHITLPYIPERAFIHEIVQTSLNKKV"
     gene            2086..2991
                     /gene="ftcD"
                     /locus_tag="ACZPB4_16140"
     CDS             2086..2991
                     /gene="ftcD"
                     /locus_tag="ACZPB4_16140"
                     /EC_number="2.1.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030409 - glutamate formimidoyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0030412 - formimidoyltetrahydrofolate
                     cyclodeaminase activity [Evidence IEA];
                     GO_process: GO:0019556 - L-histidine catabolic process to
                     glutamate and formamide [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate formimidoyltransferase"
                     /protein_id="HIR1099780.1"
                     /translation="MSTWNKIMECVPNFSEGRDLEKIDKIVAPFRAKTGVKLLDYSND
                     EDHNRLVVTVVGEPVALKQAVLEAIGVAVELIDLNKHSGQHPRMGAVDVVPFIPIRRC
                     TMEEAIALSKEVGEEVGARYAVPVFLYEKSASASYRENLAAIRKGEFEGMAEKIHQLE
                     WKPDFGPAERHPTAGTVAIGARMPLVAYNVNLGTNQLQIATDIAKKIRFIGGGLRYCK
                     AMGVELKERGIVQVSINMTDYTRTALYRAFELVRIEARRYGVPVVGSEIIGLVPMEAL
                     IDTASYYLGLEDFSMNQVLEARIME"
     gene            2995..4245
                     /gene="hutI"
                     /locus_tag="ACZPB4_16145"
     CDS             2995..4245
                     /gene="hutI"
                     /locus_tag="ACZPB4_16145"
                     /EC_number="3.5.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016812 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds, in cyclic amides
                     [Evidence IEA];
                     GO_function: GO:0050480 - imidazolonepropionase activity
                     [Evidence IEA];
                     GO_process: GO:0019556 - L-histidine catabolic process to
                     glutamate and formamide [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazolonepropionase"
                     /protein_id="HIR1099781.1"
                     /translation="MENSKILIRNAAQIVTCHGDKARRGAEMSDLGVIEDGAVAMSDG
                     VITHVGPTEEVLRNIHAEDYLEIRAENQAVLPGFVDSHTHFIFGGYREEEFSWRLRGD
                     SYMSIMERGGGIVNTMKATRESDFDTLWDRGEERLDELFSMGVTTVEGKSGYGLDLQT
                     ELVQLRVMSDLNESHPMDVVSTFLGAHAVPPEFAGRTDDYVDYMIEEVLPVIRAEHTV
                     TFCDVFCEKGVFSLEQSERLLRAARHHRFKLKMHADEIVPFGGAELAASLKCVSADHL
                     LHVSDTGIKRLARAGVVATLLPLTAFSLNEPYAPARKMIDAGCAVALASDLNPGSCFS
                     ASIPMMIALACIYMKMSPEEAVTALTINGAAAVGRASEIGSISVGKRADVILLKYPSY
                     KFLPYHVGMNLVDTVIKDGELYMM"
     gene            4281..4904
                     /locus_tag="ACZPB4_16150"
     CDS             4281..4904
                     /locus_tag="ACZPB4_16150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclodeaminase/cyclohydrolase family protein"
                     /protein_id="HIR1099782.1"
                     /translation="MLADLTIKDFLAETAGSAPVPGGGSISALNGAIAAALTEMVAHL
                     TVGKKKYAEVEGQMKTIAIEAALIRERLTEYIDKDSEAYDRVFSAFKLPKETPDEQVI
                     RTNAIQSATKEAAIVPMRVAEEIGSVMETIIYVAHKGNQNAVTDACVAMMAARTCVLG
                     ALLNVRINLTSIQDEVFVGMMRKKADELEANAIRVEQKLLDWVKTKL"
     gene            4908..>5500
                     /locus_tag="ACZPB4_16155"
     CDS             4908..>5500
                     /locus_tag="ACZPB4_16155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018667856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic amino acid lyase"
                     /protein_id="HIR1099783.1"
                     /translation="MSNVYYVGSEPLSFEGIERILTQNMKLELSPEVKERIQRCRDYL
                     DHKIEQQEGPLYGITTGFGSLCNKNISPDELSTLQENLVKSHACSVGDEVSPVIVRLM
                     MLLKAHALSLGHSGVQVITVQRILDFFNNDVLPTVYDRGSLGASGDLAPLANLFLPLI
                     GVGDVYYKGRKREAISVLDEFAWKPVKLKSKEGLALL"
BASE COUNT         1348 a         1050 c         1612 g         1490 t
ORIGIN      
        1 tgggatttgg ataatcgcta acttgtcggc gctgaatccg tgaaattcct tgcagattgt
       61 aagcacctac taaatcattc acgttatgga aatacatctt gataactatt tgccggaata
      121 tccttccttc gtttccggta ttcgccgtgc tcccgatcgc ggctattcgc ttacgcccgc
      181 tcaaacagaa acggcattga tgaacgcgct tcgttacatc cctgttgaat tacatgagaa
      241 gctagctcct gagttcatgg aggaattatt gacccgggga cggatctatg gttatcgcta
      301 ccgtccgcag ggagacctga aagcgaagcc tatctctgaa tataaaggta aatgtatcga
      361 gggaaaggcc tttcaagtaa tgatcgataa taacctctgc tttgatatcg ctttgtaccc
      421 ttacgagttg gttacgtatg gcgagactgg gcaggtctgc caaaattgga tgcaatatcg
      481 tttgattaag aagtatttgg aggagctgac cgaggagcag accttggtga tcgaatccgg
      541 gcatcctctg ggattgtttc attccaagcc ggatgcccca cgggtgatta tcacgaactc
      601 catgatggtg ggaatgttcg ataaccaaaa ggattggcat atcgccgccc agatgggagt
      661 cgctaattat ggacagatga cggccggagg ttggatgtat attggcccgc aaggtatcgt
      721 acacggtacg tttaatacat tgttgaatgc cggacgtaag aaattaggga ttccacaaga
      781 taaggatttg cgaggctatc tgtttgtatc ttccggttta ggaggaatga gtggcgctca
      841 acctaaagcc gctgtgatcg ctggtgctgc cagtataatc gccgaggtag acgcttcccg
      901 tatcgagaca cgccgatgcc aaggatgggt ccagcatgtg acggatgata tggggaaagc
      961 tttctcctta gccaacgagg cgattcgtaa gaaagaaccg atctctatcg cttttcatgg
     1021 taatattgtg gatttattgg aatatgccga taaacagggg ctttccatcg accttttgag
     1081 tgaccagacc tcgtgtcatg cggtctatga aggaggttat tgtccggtag gcgtgacgtt
     1141 tgaggaacgt acggaattat tggctcatca ccgggaagac ttttgtgctt tggtcgataa
     1201 aacgttgaag agacatttcg aggtgatcaa gcgtctggtt gcccggggta cctatttctt
     1261 tgactatggg aactccttca tgaaagcgat ctatgatgcc ggtgtacatg agatttcccg
     1321 taacggtgtg gatgagaaag atggttttat atggccttct tatgtggaag atatcatggg
     1381 gccggaatta tttgattatg ggtatggccc tttccgctgg gtatgtttaa gcggtaagcc
     1441 ggaagatttg attcgcacgg atcatgcggc tatggcgtgt atcgatccga ctcgaagagg
     1501 gcaggatatg gataattata attggatacg tgacgcggag aagaaccgtt tggtggtggg
     1561 tacgcaagcc cggatcttat atcaagacgc tgaggggcgc ttgaagatcg cccttgagtt
     1621 taaccgaatg gtacgtgatg gggaggtagg cccgattatg ttgggacgag accatcatga
     1681 cgtgagcggt acggattctc cattccgtga gacctctaat atacgggacg ggagcaatgt
     1741 gatggctgat atggcggtgc agtgcttcgc tggaaatgcc gcccggggta tgagcttggt
     1801 cgctcttcat aatggtggag gggttggtat cggtaaggcg ataaacggag gtttcggtat
     1861 ggttctcgat ggtagtgagc gggtggacga gatacttcgc tctgctatga tatgggacgt
     1921 gatggggggt gtcgctcgtc gctcatgggc ccgtaacccg aatgcgatgc gtacgagcgc
     1981 tactttcaat gagaaccgtg gcgaacagta tcatattacc ctcccgtata tcccggagag
     2041 ggcgtttatt catgaaatcg tacaaacatc attaaataaa aaggtatgag tacttggaat
     2101 aagattatgg aatgtgtccc taacttcagt gaaggacggg atctggagaa gatagataag
     2161 atcgtagcgc ctttccgggc taagacgggt gttaaactgt tggactatag taatgatgag
     2221 gatcacaatc gcttggttgt taccgtggta ggggagccag tcgctttaaa acaagccgta
     2281 ttggaggcca ttggagttgc tgttgagctg attgatttaa acaagcatag cggtcaacat
     2341 cctcgaatgg gggccgtaga tgttgttcct tttataccga ttcgcagatg tacgatggaa
     2401 gaggcgatcg ccttgtctaa ggaagtaggg gaggaagtgg gcgctcgtta tgccgtgccg
     2461 gtcttcttat atgagaaatc ggcttccgcc tcttaccggg agaatctggc ggcgatccgt
     2521 aaaggagagt ttgaagggat ggcagagaaa atccatcaac tggagtggaa acctgatttt
     2581 ggtccggccg aaagacatcc gacagccggt acggtcgcca taggtgcccg catgcctttg
     2641 gtcgcctata atgtgaactt aggaacgaat caattgcaga tcgctacgga tatagcgaag
     2701 aaaatccgtt tcatcggcgg aggtttacgc tattgtaaag cgatgggggt tgagttgaag
     2761 gaacgtggta tcgtacaggt ctctattaat atgaccgatt atacccgtac ggccttgtac
     2821 cgggccttcg agttagttcg tatcgaagct cgcagatatg gtgttccggt ggtggggagc
     2881 gagattatcg gcttggttcc tatggaggcg ttgatcgata cggcctctta ctatttggga
     2941 ttagaggact tctctatgaa tcaagtattg gaagcccgta ttatggaata gcgtatggag
     3001 aatagcaaga tattaattag gaatgctgcc cagatcgtca cttgtcatgg ggataaggca
     3061 cgacggggag cggagatgtc tgatttaggc gttatcgagg atggagccgt agcgatgtct
     3121 gatggggtta ttacgcatgt aggacctacg gaggaggtac ttcgaaacat ccatgcggag
     3181 gattatttgg agattcgggc ggagaaccaa gcggtgttac ccggatttgt agatagccat
     3241 acgcatttta tctttggcgg ttaccgggag gaggagttct cttggcgatt gcggggagat
     3301 agttatatgt cgatcatgga gcgtggtgga ggtatcgtga atacgatgaa agctacccgt
     3361 gaaagtgatt tcgatacact atgggacaga ggggaagaac gtttggatga gttattctcc
     3421 atgggtgtta ccacggtgga ggggaaaagt ggttatggtt tggatttgca aacagaatta
     3481 gttcagcttc gtgtcatgtc ggacctgaat gagtctcatc cgatggatgt cgtatcgacc
     3541 tttttgggtg ctcatgctgt tcctcctgaa tttgccggtc gtacggacga ttatgtggat
     3601 tatatgatcg aggaagtgct tcctgtcatc cgagccgaac atacggttac gttttgtgat
     3661 gtgttttgtg agaaaggcgt tttctcgtta gaacagagtg agcgcttgct tcgtgccgcc
     3721 cgtcatcatc gttttaaatt gaagatgcat gcggatgaga tcgttccttt cggaggggcg
     3781 gaactggcgg cctccttgaa gtgtgtaagt gctgatcatt tattacatgt atcggataca
     3841 ggcatcaaac gtctggcaag agcgggtgtc gtggctacct tacttccgct gactgccttt
     3901 tccttgaatg agccgtatgc gcctgcccgg aagatgatag atgccggttg cgcggtggct
     3961 ttagcttccg atctaaatcc gggaagttgt ttttcggcct cgatcccgat gatgatagcc
     4021 ttggcctgta tctatatgaa gatgagccct gaagaagcgg taacggcatt gaccattaat
     4081 ggagccgcag ctgtgggacg tgcctccgag attggaagta tcagcgtggg aaaacgtgcg
     4141 gacgtgatct tgctgaaata cccgtcttat aagtttctac cttatcatgt gggaatgaat
     4201 ctcgtggata ccgtaattaa ggatggggaa ctttatatga tgtaagataa gaattgttga
     4261 atcatttaaa tcaaaatact atgttagcag acttgacaat taaagatttt ttggcggaaa
     4321 cggcgggtag tgctcccgtt cccggtggtg gaagtatatc tgccttgaat ggcgctatag
     4381 cggcagcttt gacagagatg gtggcccatc tgactgttgg caaaaagaaa tatgcggaag
     4441 tggaaggaca aatgaaaacg atcgctatcg aggcggcttt gatccgtgag cgtcttactg
     4501 aatatattga taaggacagc gaggcttatg atcgtgtatt ctccgctttt aagttgccga
     4561 aagaaacgcc tgacgaacag gtgatccgta cgaatgcgat acagagcgca acgaaggagg
     4621 cggctattgt tccgatgagg gtggcggagg agatcggttc cgtaatggag acgataatct
     4681 atgtggctca caaaggtaat cagaatgccg tcacggatgc ttgcgtggcg atgatggctg
     4741 cccgtacttg tgtattgggg gctttattga atgtccgaat taacttaacg tccatccaag
     4801 acgaggtgtt cgtcggaatg atgcggaaga aagcggatga actggaggcg aacgctatcc
     4861 gtgtagagca aaagttattg gattgggtga agactaaatt atagcatatg agtaatgttt
     4921 attatgtggg ttccgagcct ctctcttttg agggaatcga acggatactt actcaaaata
     4981 tgaagttgga gctttcaccc gaggtgaagg agcgcatcca gcgttgccgg gattacttgg
     5041 atcataagat cgagcaacag gaggggcctt tgtatgggat tactaccggt ttcgggtcct
     5101 tatgtaataa gaatatctct ccggacgaat tgagcacctt gcaagagaac ttggtgaaaa
     5161 gtcatgcctg tagcgtaggg gatgaggtaa gtccggtgat cgttcgtttg atgatgttat
     5221 tgaaagcgca tgccctttcg ttggggcata gtggcgtaca ggtgatcacc gtacaacgta
     5281 ttctggattt tttcaataat gacgtgcttc cgaccgtgta tgatcgtggc tctttaggcg
     5341 cttccggtga tttggcgcct ctggcgaatt tgttcctgcc tctgatcggc gtgggtgatg
     5401 tttattataa gggccgcaaa cgggaagcga tcagcgtatt ggacgagttc gcttggaagc
     5461 ctgtgaagct gaaaagcaag gaggggttag ctttattgaa
//
LOCUS       DBMDTB010000160         5291 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_3794_length_5291_cov_11.010983, whole genome shotgun sequence.
ACCESSION   DBMDTB010000160 DBMDTB010000000
VERSION     DBMDTB010000160.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 5291)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 5291)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5291
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_3794_length_5291_cov_11.010983"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..953)
                     /gene="trpB"
                     /locus_tag="ACZPB4_16160"
     CDS             complement(<1..953)
                     /gene="trpB"
                     /locus_tag="ACZPB4_16160"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - L-tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HIR1099784.1"
                     /translation="MKTYQVDKNGYYGEFGGAYVPEILHQCVENLQNTYLQVLESDSF
                     KEEFDQLLRDYVGRPSPLYLAKRLSEKYGCKIYLKREDLNHTGAHKINNTIGQILLAR
                     RMGKTRIIAETGAGQHGVATATVCALMNMECIVYMGKTDVERQHANVQKMEMLGATVV
                     PVTSGNMTLKDATNEAIRDWCCHPSDTYYIIGSTVGPHPYPDMVARLQSVISEEIKKQ
                     LLEKEGRDHPDYLIACVGGGSNAAGTIYHFVDDERVKIVLAEAGGKGIHSGMSAATIQ
                     LGKEGIIHGARTLVMQNEDGQIEEPYSVSAGLDYPGIGPIHA"
     gene            1405..2838
                     /locus_tag="ACZPB4_16165"
     CDS             1405..2838
                     /locus_tag="ACZPB4_16165"
                     /EC_number="4.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005841516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008797 - aspartate ammonia-lyase activity
                     [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA];
                     GO_process: GO:0006531 - aspartate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate ammonia-lyase"
                     /protein_id="HIR1099785.1"
                     /translation="MDTKLTGKTRIESDLIGAREIPAEALYGVQTLRGIENFSISKFR
                     LSEYPLFIKGLAITKMAAAMANFELGLLTVEQKDAIIAACGEILDGKHHDQFPVDMIQ
                     GGAGTTTNMNANEVIANRALELMGYERGEYQYCSPNDHVNCSQSTNDAYPTAIHIGMY
                     FKHLQLLPHLEELIASFRKKGEEFSQIIKMGRTQLEDAVPMTLGQTFNGFASILQDEI
                     AHLNEAAADFLVVNMGATAIGTGICAEPGYAEKCIAALREITGWDIRLSSDLVGATSD
                     TSCLVGYASAMKRVCVKMNKICNDLRLLASGPRCGLGEFNLPAMQPGSSIMPGKVNPV
                     IPEVMNQIAYKVMGNELCVTMAGEAAQMELNAMEPVMAQCCFESVDLLINGFDTLRTR
                     CVDGIVANEDRCREEVHHSIGVVTALNPVIGYKNSTKIAKEALETGVSVYQLVLDHGI
                     LTKEELDTILSPENMIKPVKLDIKPRR"
     gene            2957..3892
                     /locus_tag="ACZPB4_16170"
     CDS             2957..3892
                     /locus_tag="ACZPB4_16170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HIR1099786.1"
                     /translation="MINRRDFLKNASLFTLGGLMAGKVGSADAAKPVTSETMAAKTVG
                     LQIYSLGKELYADVPGGLKKIKQMGYTNLELAGYKEGKIGGVDMMEFKKMVDDAGLKI
                     TSSHVNPPVREYTKANRSQISEYWKKTADDHAKLGVKYLIQPGQPSTRSTEETAFVCE
                     IFNEAGKIVKAAGIPFGYHNHEMEFAKVNPGSTEAKLGRRVKGDCIYELFLKNTDPSL
                     VFFEMDVYWAVMGQQDPIEWLKKYPNRIKVLHIKDRAILGESGMMNFENIFQQAYANG
                     IKDYFVELEGMPDGRSQFEGVKGCVDYLLKAPFVK"
     gene            complement(3943..4515)
                     /locus_tag="ACZPB4_16175"
     CDS             complement(3943..4515)
                     /locus_tag="ACZPB4_16175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma-70 factor"
                     /protein_id="HIR1099787.1"
                     /translation="MDENAERISLELIAGDEQAFDTVYKQYYRGLCAFASQYVTVPES
                     EEIVQDVMMWLWENRKSLVADMSLKSLLFTIVRNKCLNTISHIQVKQQVHERLYAKFQ
                     EQFENPDFYIGELMALASKAIRELPDEYRKAFEMNRFEEMTYNEIAERTGVSPKTIAY
                     RISQALKILRTKLKDYIPLLVWLLYEQTRS"
     gene            complement(4582..>5291)
                     /gene="gpmA"
                     /locus_tag="ACZPB4_16180"
     CDS             complement(4582..>5291)
                     /gene="gpmA"
                     /locus_tag="ACZPB4_16180"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005789269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004619 - phosphoglycerate mutase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HIR1099788.1"
                     /translation="WNKENRFTGWTDVDLTEKGVAEAYRAGNLLKEKGYVFNKAYTSY
                     LKRAVKTLNCVLDRMDQDWIPVEKSWRLNEKHYGSLQGLNKSETAQKYGDEQVLIWRR
                     SYDIAPLPLSEGDPRNPRFDIRYKDVPDKELPRTESLKDTVERILPYWKEVIFPTLRT
                     ADQILVAAHGNSLRGIIKYLKNISDEEIVHLNLPTAVPYVFEFDGDLKLVNDYFLGDP
                     EEIKKLMEAVANQGKKK"
BASE COUNT         1286 a         1188 c         1334 g         1483 t
ORIGIN      
        1 gcgtggatcg ggccgatgcc cgggtaatcc aagccggcgg aaacagaata aggttcctcg
       61 atctgtccgt cctcgttctg catgaccaag gtacgtgccc cgtggatgat gccctcttta
      121 cccaattgga tcgtggcggc gctcatgccg gagtggatgc ccttgccgcc ggcctcggcc
      181 aatacgatct tcacccgctc gtcgtccacg aaatgataga tcgtaccggc ggcgttactt
      241 cccccgccta cgcaggcgat caggtaatcc gggtgatccc ttccttcctt ctccagcagt
      301 tgcttcttga tctcctcgct gataacggat tgcagccggg ctaccatatc cggataagga
      361 tgggggccta ccgtagaacc gataatataa tacgtatccg aaggatgaca gcaccagtca
      421 cggatcgcct cgttcgtggc gtctttcaag gtcatgtttc ccgaggtcac gggcacgacg
      481 gtagctccca gcatctccat cttctgtacg ttggcatgtt ggcgttccac gtctgtcttc
      541 cccatataaa cgatacattc catattcatc aaggcacata ccgtagccgt agccactcca
      601 tgctgtccgg cacccgtctc ggcgatgata cgggtcttcc ccatgcggcg ggctaggagg
      661 atctggccga tcgtattgtt gatcttatgt gctccggtat ggttcaagtc ttcccgtttc
      721 aaatagatct tgcatccgta cttctcgctc aaccgtttcg ccaagtaaag aggggagggg
      781 cggcctacat aatcacgcaa taactgatcg aactcttcct tgaagctatc gctctccaac
      841 acttgcagat aggtattctg taaattttcc acgcattgat gaaggatctc gggaacatag
      901 gccccgccga actcaccata gtaaccattc ttgtcaactt gatacgtttt catcttttat
      961 ctattttagt tatttccctt ttgaatttgc cataaaaaga aaagaggcct gccgcaagtg
     1021 cgacagacct ctttatatct ttatgtagtg tttatatata catacgagtc ttcgttcctt
     1081 acgacctttt gagttgtacg gagcgccacc accaatatgt atttactacg aatgttctca
     1141 tgactctgtt ttgttattac ggcagcaaat atatggaatc tttgacaaac agcaaataaa
     1201 atcgtgtttt ttttatgaat gagataaaaa agatcagaag gtctattaaa actgctctat
     1261 tgacaaattg taatttattg agccttgtat agacgtgtat tggcgttttt ggtatttgtt
     1321 tttattattt cgaagaataa tttgctttca aaataatagt ttctaccttt gcggaaacaa
     1381 taaaaaacga ttaatatttc taatatggat actaaattaa ctggaaaaac tcgcatagag
     1441 agcgatttga tcggcgctcg tgaaatcccc gccgaagcat tatacggagt tcaaaccttg
     1501 agaggaatcg agaatttctc aatcagtaaa ttccgtttga gcgaatatcc tttattcatt
     1561 aaaggattag ctataacaaa aatggcggct gccatggcta actttgaatt aggcttgctt
     1621 accgtagagc aaaaagacgc tatcatcgcc gcttgtgggg agattctcga tggtaaacat
     1681 cacgaccagt tcccggtgga tatgatccaa ggcggagcgg gtaccactac gaatatgaat
     1741 gcgaatgagg tgatcgccaa ccgtgccttg gagctgatgg ggtatgagcg gggtgaatac
     1801 caatactgct caccgaacga ccatgtgaac tgctcgcaat ccacgaacga cgcatatccg
     1861 accgctatcc atatcggtat gtattttaag catcttcaat tgcttcccca tttggaggaa
     1921 ttgatcgcct ctttccgtaa gaaaggagag gagttctcgc agattatcaa gatgggacgt
     1981 acgcagttgg aggatgccgt acctatgacg ttggggcaga cctttaatgg cttcgccagc
     2041 atcttgcagg atgagatcgc tcacttgaat gaggccgccg ccgatttctt ggtggttaat
     2101 atgggagcta ccgctatcgg tacgggtatt tgtgccgagc cgggatatgc ggagaaatgt
     2161 atcgcggctt tacgtgagat aaccggatgg gatatccgtc tctcctccga tttggtagga
     2221 gctacctcgg atacttcttg cttggtaggc tatgcttccg ccatgaagcg ggtttgcgtg
     2281 aagatgaata agatatgtaa tgaccttcgc ttgttggcaa gcggtcctcg ttgcggtttg
     2341 ggtgagttta acttgcctgc tatgcagccg ggttcgtcta tcatgccggg taaggtgaat
     2401 ccggtgatcc cggaggtgat gaaccagatc gcttataagg taatgggtaa tgagctatgc
     2461 gtgaccatgg ccggggaagc cgcccagatg gagctgaacg ccatggagcc ggtgatggca
     2521 caatgctgct tcgagtccgt ggatttgctg atcaatggtt tcgatacctt gcgtacccgt
     2581 tgcgtggacg gtattgtcgc taacgaggat cgttgccgtg aggaggtaca tcatagcatc
     2641 ggcgtggtga cggccttgaa tccggtaatc ggctataaga actcgaccaa gatcgcgaag
     2701 gaggcgttgg agaccggcgt tagcgtttat caattggtac tggatcatgg tatcttgacc
     2761 aaggaggaat tggatacgat cttaagcccg gagaatatga tcaagccggt gaagttggat
     2821 atcaagcctc gccgttaatc gagtcctatt atataatgta taccatttgt ggaccgtata
     2881 ggtggatttt tccatcctat gcggtctttt tttagattat aatctctatc tttggactga
     2941 cttaattcta ataatcatga taaatagacg agatttttta aagaatgcgt cccttttcac
     3001 cttgggtggc ctgatggccg gaaaggtcgg gagcgcagat gcggctaaac ctgtcacttc
     3061 tgaaacgatg gccgctaaga cagttggttt acaaatctat tctttaggca aggaacttta
     3121 tgcggatgta cccggtggat tgaaaaagat caagcaaatg gggtacacga atctggaatt
     3181 ggccggttac aaggaaggca agatcggcgg tgtagacatg atggaattca agaagatggt
     3241 ggatgatgcc ggattgaaga tcaccagttc ccacgtgaat cctccggtac gtgagtacac
     3301 gaaggccaat cgctcccaga tctccgagta ttggaagaag acggctgatg accatgccaa
     3361 actaggcgtg aagtacttga tccagcccgg gcaaccgagt acccgtagta ccgaggaaac
     3421 cgctttcgtc tgcgagattt ttaacgaggc gggtaagata gtgaaagcgg ccggtattcc
     3481 tttcggctat cacaaccatg agatggagtt cgccaaggta aatccgggta gtacggaggc
     3541 caagctggga aggcgtgtga aaggagattg catctatgag ttgttcttga agaatactga
     3601 tccttcgctt gtatttttcg agatggatgt ttattgggcc gtgatgggac aacaagatcc
     3661 gatagagtgg ttgaagaaat atccgaaccg tattaaggta ttgcacatca aggaccgtgc
     3721 tattctaggc gagtccggga tgatgaattt cgagaatata ttccagcaag cttacgcgaa
     3781 tggaatcaag gattatttcg tggagttgga gggtatgcct gacggacgtt cccagtttga
     3841 gggcgtgaaa ggctgcgtgg attatttatt gaaagcaccg ttcgtgaaat aagtcttttg
     3901 actcattaaa aaaacgctca tggcggtagg atgcttcctc cgttatgagc gtgtttgttc
     3961 gtaaagcagc cataccaata aagggatata gtcctttaat ttcgtccgta atatcttgag
     4021 cgcttgagag atgcggtatg cgattgtttt gggggatacg cctgtccgct cggcgatctc
     4081 gttgtaggtc atttcctcga aacggttcat ctcgaatgcc ttacggtatt catccgggag
     4141 ctcccggatg gccttggagg ccaaggccat cagttctcct atataaaaat caggattctc
     4201 gaattgctct tggaacttgg cgtacaatct ctcgtgcact tgttgcttaa cctgtatgtg
     4261 gctgatcgta ttgaggcatt tattgcggac aatggtgaag aggagtgatt tcagggacat
     4321 gtccgctact agggattttc ggttttccca cagccacatc atcacgtctt gtacgatctc
     4381 ctccgattct ggtactgtta catattggga ggcgaaggcg cacaatcccc ggtaatattg
     4441 tttgtacacg gtgtcgaacg cttgttcgtc tcctgcgata agttctagtg aaattcgttc
     4501 tgcgttctcg tccacaatag tgtttaagtt tgtttggttg caaacttaat gaataattcc
     4561 ggataagagg catgaatccc gctacttttt ctttccttgg ttggctacgg cttccatgag
     4621 tttcttgatt tcctccgggt cgccaaggaa ataatcattc acgagtttca agtcaccatc
     4681 gaactcgaac acgtatggaa cggctgtcgg gagattcaga tgaacgatct cttcatcgga
     4741 gatgtttttt aaatatttga tgattccccg caagctgttt ccgtgagcgg cgacaaggat
     4801 ctggtcggcg gtccggagcg tcgggaagat aacctctttc caataaggga gaatccgctc
     4861 aaccgtatct ttcaaggatt ccgtacgggg caactcttta tccggcacgt ctttgtagcg
     4921 gatatcgaag cgagggttac gagggtcgcc ttccgatagg ggaagcgggg ctatatcgta
     4981 actgcgacgc cagatcaaga cttgctcgtc tccatacttt tgggcggtct cgctcttgtt
     5041 caacccttgt agcgatccgt aatgtttctc gttcagcctc cagctcttct ccaccgggat
     5101 ccagtcttgg tccatgcgat ccaatacaca attcaaggtt ttgacggccc gttttaaata
     5161 agaggtatag gctttattga acacatatcc tttttctttc aataggttgc cggccctata
     5221 agcttcggcc acgccttttt ctgtcaaatc cacatcggtc caaccggtga accggttctc
     5281 tttattccat a
//
LOCUS       DBMDTB010000161         5222 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_3869_length_5222_cov_12.308143, whole genome shotgun sequence.
ACCESSION   DBMDTB010000161 DBMDTB010000000
VERSION     DBMDTB010000161.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 5222)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 5222)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5222
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_3869_length_5222_cov_12.308143"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..534)
                     /locus_tag="ACZPB4_16185"
     CDS             complement(<1..534)
                     /locus_tag="ACZPB4_16185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099789.1"
                     /translation="MKRIGFIFTVITLFCLSAVSRVIAQSDWSLINFDLINLPCEPGS
                     HSLTYTMYYGVNPFKVKSFNDIECPIIFGGELVCTRSIDLKEKKEAVNRALSDLGWNF
                     ATLRQVIERAAQAKPNDITNEQFWDDLVSMSGLNGLAGDALALISGVKDRDKYYEAER
                     IQGRLKSEAYKYLVNKTL"
     gene            complement(531..1544)
                     /locus_tag="ACZPB4_16190"
     CDS             complement(531..1544)
                     /locus_tag="ACZPB4_16190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099790.1"
                     /translation="MKKLSILLLSLAAMGAFAFVLPSLPTGQSGAYPTETAFMAEAEE
                     MFQKGNKLYEQGYMLQANYYYGQAVVAVASLRYGLSELIYVKQRDERAAAKKAAEEKQ
                     RKEDEEDMEDWGWEDEGGLLTALTNLTGKLDTMTEKLSQELVNMELDEDSKRSEAWDL
                     LATQSIASPYPYFFEAISWDYKGKEDKARECYANAMCNPAFPSTVWDFSYWQDLTSGE
                     LRAIARRLLPKEEEYRKYFHLSTYSCPHHYLNFDDDYLTAKAADTLVVLPTAVGAALM
                     LYETAVQANPFNARNFAGASLLSVQNGDSVKAAYYLNEGLLIDPENKGLQALLNVWKG
                     GHK"
     gene            complement(1591..2535)
                     /locus_tag="ACZPB4_16195"
     CDS             complement(1591..2535)
                     /locus_tag="ACZPB4_16195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099791.1"
                     /translation="MKKKFYILMCLASLVLMVTACGGKEKIKEKLRAATEAVKERKEA
                     AASEKGSDLEMDKQGDRPDNGAFVDPSLTPAQRKAIDKENPWFARNFRMELTAKSMGN
                     KVNVEIQKSGKILYYHFWNNSGNVETLILLDEGDYKIYQISSKNKVAQLKATSDSDYY
                     AFFCDKIGNVYGIVHTAQKEKKVEQDDSFVQSSTQESVGVEDVRWGGFDCEKITRVTG
                     TENDLSAGMKAIGDLFGTKSSMDNSIKDLKHIETTDIVWIEKNSGAVVHRKFSVKGGA
                     GMGNYAERMKPQPSVTLLTFSPDPSLIPTSQEGYKLVK"
     gene            complement(2552..3889)
                     /locus_tag="ACZPB4_16200"
     CDS             complement(2552..3889)
                     /locus_tag="ACZPB4_16200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HIR1099792.1"
                     /translation="MKKLVFILSAMLLLIGTMDVQAQWGKKLLKKAGESAKRATERNV
                     ERKVEQTVDKAFEGAEDVVTGKGNNNNEKEEPPTSTNSQGNFETMDDGEDLAQQEQQQ
                     PQQSLEMTYAKSDFVPGDEIIFEDDVTREQIGEFLSQWDLLKGTVEIAQINGDKVILC
                     VSQDDPVIAPLFDNMKSYLPEKFTLEFDFWVGPFTKKGDDEPENCYIVRFYKPESGSR
                     VQTINLDDWYYSASDHRTRLRWDFIPSSGENSRSGSDDSFRTIPNSWNHFSLSFNQRA
                     MKVYINGIRYANIPNTVAPGHFDIQFYRGGGYFTNNTSIRNIRVAKGAVPLYDRMMSD
                     GKFITYGITFDVGKSTIKPESMGEINRIVKLMTDNPDLRFSVEGHTDSTGNEASNQTL
                     SEARSNAIVGKLVELGISADRLSASGKGQSSPIADNGTDEGRAKNRRVEFVKM"
     gene            complement(3926..4171)
                     /locus_tag="ACZPB4_16205"
     CDS             complement(3926..4171)
                     /locus_tag="ACZPB4_16205"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099793.1"
                     /translation="MEEEKHKKPLLSYEEVIEVIDERISRDEPATADERIKRVEEVAE
                     QMEEERKKGISCRKKVSRFFRRSLINLDRSIRRCFGK"
     gene            complement(4322..>5222)
                     /locus_tag="ACZPB4_16210"
     CDS             complement(4322..>5222)
                     /locus_tag="ACZPB4_16210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HIR1099794.1"
                     /translation="HIFKAFYLGETGGAGTMGTGIGLSLVRQMVRSMEGRVSVKSTAG
                     VGSEFVVMLPLRHGDSFWERWVPGEESNDNASHPEPDKTVILPDATMEPDSTSMRPSI
                     LIVEDNADISYYIGRLLNGAYQIIYAQNGAEGLEIAAEQMPDLILTDLMMPEMDGYEL
                     CRRVRESEVLNHIPIIIITAKSGGKERVCGLEVGADAYLEKPFNAEELNIRITKLLEQ
                     RRLLREKYSKAMREGTELNVKLNPADQDFLARLNDYIYALISNHGLNSDMVDDKMCMS
                     RSQLNRKVRAITGYNTSAYTLIS"
BASE COUNT         1139 a         1464 c         1167 g         1452 t
ORIGIN      
        1 gagtgtctta ttcaccaagt atttgtacgc ctcgctcttg agccgtccct gtatcctctc
       61 cgcctcgtaa tacttgtcgc gatccttcac gccgctgatc agcgccaacg cgtctcccgc
      121 caggccgttc aacccgctca tgctcacgag gtcgtcccag aattgctcgt tcgttatatc
      181 gttcggcttg gcttgcgccg ccctttcgat cacttgccgc agcgtggcga aattccagcc
      241 caggtcgctt agggcccggt ttaccgcctc cttcttttct ttcaggtcga tggatctggt
      301 gcagaccaac tctcccccga agatgatggg gcactctata tcgttaaacg acttaacctt
      361 aaacgggttg actccgtaat acatggtata ggtcaacgaa tggcttcccg gctcgcaagg
      421 caggttgatc aagtcgaagt ttatcaagct ccaatccgat tgcgctatca cccgggaaac
      481 agcggacaag cagaatagcg ttatcacggt aaatatgaat cctatgcgtt tcatttgtgt
      541 cctcctttcc atacgttcag taatgcttgc aatcctttat tctccggatc tatcagcagc
      601 ccctcgttca ggtagtaggc ggcctttacg ctatcgccgt tctgtacgct cagcaacgag
      661 gcaccggcga aattgcgtgc gttgaagggg ttcgcctgta cggccgtctc atacagcatg
      721 agcgccgctc ccacggccgt gggtaatacg accaaggtgt cggcggcttt cgccgtcagg
      781 tagtcatcgt cgaaattaag gtaatggtgc gggcagctat aggtgctcag gtgaaaatac
      841 ttgcggtatt cctcctcctt ggggagcagc ctgcgggcaa tggccctgag ctcgccgctc
      901 gtaaggtcct gccaatagga gaaatcccat acggtggacg ggaaagcggg gttgcacatc
      961 gcgttggcgt agcattctct cgccttatct tcctttccct tgtaatccca cgagatggcc
     1021 tcgaagaagt aagggtaagg cgacgctatg ctttgggtag ccaacaagtc ccaagcctcg
     1081 ctccgcttgc tgtcctcatc caattccata ttgacaagct cctggctcag tttttcggtc
     1141 atcgtatcca gcttcccggt taggttggta agcgcagtaa ggagtcctcc ctcatcttcc
     1201 catccccaat cttccatatc ttcctcgtcc tccttgcgct gtttctcttc ggcggctttc
     1261 ttggcggcgg ccctctcgtc gcgctgtttt acgtagatca gctcgctcaa cccgtagcga
     1321 aggctggcca cggctaccac ggcttgcccg taatagtagt tcgcctgtag catatagcct
     1381 tgctcgtaaa gcttgttccc tttttggaac atctcttcgg cctcggccat aaaagccgtt
     1441 tccgtaggat aagcgccact ttgcccggtg ggcaaggaag gcaagacgaa agcgaatgct
     1501 cccatagcgg caagactgag tagtagaatc gatagcttct tcatggcttt cttatttgag
     1561 cgtgttatac attctatatt atatgaatac ctatttcacc agtttatagc cctcctgaga
     1621 ggtcggtatc aacgacggat cgggcgagaa ggtgagcaac gtgacggagg gttgcggttt
     1681 catccgttcc gcatagttac ccattccggc tcctcctttc acggagaact tgcggtgtac
     1741 cacagctccg ctattctttt caatccagac gatgtcggtc gtctcgatat gtttcaagtc
     1801 tttaatcgag ttgtccatgc tggatttagt gccaaagagg tctcctatgg ctttcatccc
     1861 ggcactcagg tcgttctcgg taccagtgac acgggtgatc ttctcacaat cgaagccgcc
     1921 ccaacgcacg tcctctaccc cgacagattc ttgcgtgctg gactggacaa agctatcgtc
     1981 ctgttccacc ttcttctctt tctgagcagt atggacaatg ccatacacat tccctatctt
     2041 gtcgcaaaag aacgcataat agtccgagtc ggaagtcgcc tttagctgcg ccaccttgtt
     2101 tttagacgaa atctggtaaa tcttataatc gccttcgtca agcaggataa gcgtctcgac
     2161 attgccagag ttgttccaga aatggtaata aaggattttg cccgactttt gtatttccac
     2221 gttcaccttg ttccccattg acttagctgt cagttccata cggaagttgc gagcgaacca
     2281 cggattctcc ttgtcgatcg ccttacgctg ggccggcgtg agcgacggat cgacaaaggc
     2341 accgttatcc ggcctgtcgc cttgtttatc catttccaga tcgctcccct tttcggaggc
     2401 ggccgcttcc ttccgctcct ttacggcctc ggtagccgca cggagcttct ccttgatctt
     2461 ctccttgccg ccgcaagccg tcaccatcaa gacgaggctc gccaagcaca tcagtatgta
     2521 gaatttcttt ttcatatcgc tcacttattc gttacatctt gacaaactcc acccgccggt
     2581 tcttggcacg accctcgtcc gttccgttat cggcgatggg agatgattgt cctttgccgg
     2641 aagcggagag gcgatcggca ctgatgccca gttcaaccag tttacctacg atggcgttgc
     2701 tgcgggcctc gcttaacgtc tggttggaag cctcgttgcc ggtgctatcg gtatggcctt
     2761 ctacggagaa tctcaggtcg gggttatcgg tcattaattt gacgatacga ttgatctcac
     2821 ccatactctc tggtttgatg gtggacttgc cgacatcgaa ggtgatgcca tacgtgatga
     2881 acttaccgtc gctcatcatg cggtcgtaca atggcactgc gcctttggcg acacgtatgt
     2941 tgcggatgga agtgttattc gtaaaatatc caccgcctct ataaaactgt atgtcaaaat
     3001 gtccgggtgc taccgtattc ggaatattgg catagcggat accatttatg taaactttca
     3061 ttgcccgttg attgaaggac agtgagaagt ggttccatga gttcgggata gtccgaaaag
     3121 agtcatcgct tccgctacgg ctgttctccc cagaggaagg aataaagtcc catcttaggc
     3181 gtgtacgatg gtctgaagca ctataatacc agtcgtcaag attgatagtt tgaacacgac
     3241 ttcccgattc gggtttgtaa aaacgtacga tatagcaatt ttccggctca tcatctccct
     3301 tttttgtaaa aggccctacc caaaagtcaa attccagcgt gaacttttcc ggcaaataac
     3361 ttttcatatt atcgaatagc ggtgcaatga ccggatcatc ctgactcacg caaagtatca
     3421 ccttatcgcc attgatttga gcgatctcaa cagtaccttt taataaatcc cactggctga
     3481 ggaattctcc tatctgttcc cgggtcacat catcctcaaa aataatctca tcccccggca
     3541 cgaagtcact cttggcatac gtcatttcga gtgattgctg tggttgttgc tgttcctgct
     3601 gtgccagatc ttccccatca tccatagttt caaaattccc ttgtgaattt gtacttgttg
     3661 gtggctcctc cttttcatta ttattattcc ctttccccgt caccacatcc tccgctccct
     3721 cgaaagcctt gtctacggtc tgttccactt tccgttccac gttcctctcc gttgcccgtt
     3781 tggcactctc acccgctttc ttgaggagtt tctttcccca ttgggcttgc acgtccattg
     3841 tcccgattag gagcaacatg gcagataaaa taaatactag ctttttcatt tcctttaatt
     3901 cattagatta ataattcatt cctatttatt taccgaaaca ccttctgatg gatcggtcca
     3961 gatttatcaa ggatctccga aaaaagcgag aaaccttctt acggcacgat atcccttttt
     4021 tacgttcttc ttccatttgc tcggccactt cctcgacacg tttgatccgc tcgtcggcag
     4081 tggcaggctc gtcacgcgag atgcgctcat cgatgacctc gatcacctcc tcataagaaa
     4141 gcaaaggctt cttgtgtttt tcttcttcca tactcgaacc agatttggtg aaacgtccga
     4201 tttctttatt cgcaaaatta gccccgagag cgatcgcccg tgaggagaaa tgacgcattc
     4261 ttataggata atcgacgcat ttcactagga caaaccaaga gaatctgcgc attgaaaata
     4321 attaactaat taaagtatag gcggaagtgt tgtagcccgt gatggcacgg accttgcgat
     4381 tcaactggga tcggctcatg cacatcttat cgtctaccat gtccgagttc aagccatggt
     4441 tggatatcaa cgcatatata taatcattca ggcgagccaa gaagtcttgg tcggcagggt
     4501 ttagttttac attcagttct gtcccctcac gcatagcctt ggaatacttc tcacgcagca
     4561 aacgacgctg ttccagcaac tttgttatcc ggatattcag ctcttccgca ttgaaaggct
     4621 tctccagata agcgtccgcc ccgacttcta agccacagac acgttccttt cctcctgatt
     4681 ttgcggtaat gataatgatc ggaatatggt tcaacacctc ggattcacgt acccgcctac
     4741 ataactcata gccatccatc tcgggcatca tcaagtcggt gaggatcaag tccggcattt
     4801 gctccgccgc tatctccagc ccctccgctc cgttttgcgc atatattatt tgatacgcac
     4861 cattaagcag ccggccgata taataagaaa tgtccgcatt atcttccacg atcaatatag
     4921 acgggcgcat agacgtgcta tccggctcca tcgtcgcatc cggcagtatc acggtcttgt
     4981 ccggttccgg atgagaggcg ttatcgttag attcctcgcc gggtacccaa cgttcccaga
     5041 aggagtcgcc atgtctcaat ggcaacatca cgacaaactc agaaccaacc ccggccgtac
     5101 tcttcacgct cacccggccc tccatgctcc tcaccatctg ccgtaccaaa gaaaggccga
     5161 tccccgtgcc catcgtgcct gcccctccgg tctcacctag gtaaaaagcc ttgaagatat
     5221 gc
//
LOCUS       DBMDTB010000162         5174 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_3917_length_5174_cov_13.571851, whole genome shotgun sequence.
ACCESSION   DBMDTB010000162 DBMDTB010000000
VERSION     DBMDTB010000162.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 5174)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 5174)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5174
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_3917_length_5174_cov_13.571851"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..1431
                     /locus_tag="ACZPB4_16215"
     CDS             <1..1431
                     /locus_tag="ACZPB4_16215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor domain-containing
                     protein"
                     /protein_id="HIR1099795.1"
                     /translation="LKAGGTVKYGDVTSFQNENRLASFMGRFNYMYDNRFIATVNLRA
                     DGSSKLGMNNKWGFFPSASAAWVLNEEAFLKDVDWLSQLKLRAGYGLTGNQDAIEAYN
                     SLALMSPNGVTSVNGNSTATYGFTRNSNPDLRWEVKKTFDVGVDAGILDGRFTLTADW
                     YTSKTTDLLYKYAVPVPPFVYPELLANLGEMTNSGVELAVSGGIVKTKDFDFNMGVNF
                     SYQKNKLNSLSGSYMGQELQAKQYMDLSSMSGAGFVGNNRVVYQMVGQPVGVFYIPRC
                     LGLTPALDENGNAIEGRYIYNLDQTIDGKEGLDTNDGGDRYIAGQAMPKYYLGMNFSF
                     RYKRFDLMTQMNGAFGHKIFNGTSLAYMNLSQFPTYNALAKAPESKIYDQSISDYWLE
                     KGNYLNIDYITLGYNIDCKKIEKYVKNIRVTFSVNNVATITGYSGLSPMINSTTVDKD
                     NNDLGMDNKRFYPLSRTYSLGLSVNF"
     gene            1448..3115
                     /locus_tag="ACZPB4_16220"
     CDS             1448..3115
                     /locus_tag="ACZPB4_16220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RagB/SusD family nutrient uptake outer membrane
                     protein"
                     /protein_id="HIR1099796.1"
                     /translation="MKKKFIYSFMIAAAAAAFSSCSNFLEERPTDAFDEETAFQSPTL
                     VYVNTVASLYNNMFKIMGNDRHVYDLNTFSSDEAMLPCRIGDWEDGGLWQNIFLHRWG
                     TMNDLTKNSWDFLYEQIGKCNQSVDKLQAFAEEQPDVEYFKVYLEEVRAVRAFFYYEL
                     LDLFARVPLVTSSTTPMSEVKQSERSVVFNFVRSELEEALPYLSDNRSNQKGEYYGRI
                     TKPVAYMILAKLALNAEVYADDNWTDGNRPDGKNIKFTVDGKEMNAWEATIAYVDKLE
                     ALGYKLQGNFSENFAVANETSVENIFTVPMDPVAYPDAKDYNVVRTRHYDHATAYGQS
                     GWNGSCATVKAMNVFKFGTADEDPRCKLTYFTGEVTGPDGKTIYTEWDGQKVPLKYEP
                     NAPKVYMDASDGLLVKTAGARMAKYEFDQNAQDGGNLHGNDCVIFRFADALLMKAEAK
                     IRLGQNGDDEVNQVRNRVGAKPLQNVTLDTLLDERMLELAWEGVRRQDLIRFGKFTEA
                     TVDRYVGVKHSASSLDYQEDKTGYTTVFSIYADILSLNPNLTQNPGY"
     gene            complement(3160..4536)
                     /locus_tag="ACZPB4_16225"
     CDS             complement(3160..4536)
                     /locus_tag="ACZPB4_16225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009016547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HIR1099797.1"
                     /translation="MKNKYEARLGTERMLPLVFKMALPAVAAQFVNLLYNIVDRIYIG
                     HIPEIGTNALAGIGVTTSIVILISSFSAIVGAGGSPLAAIALGQGDRERAGKIVGNGF
                     ILLILFTIFTSLITYTFMEPILLFTGASKYTLGYAVDYLSIYLLGTLFVEISTGLNAF
                     INAQGRPSIAMCSVLIGALLNIVLDPIFIFWLDMGVKGAALATILSQACSAIWVLSFL
                     FSRRASLPLERRYMRLDRRIVLSMFALGISPFIMASTESLVGFVLNSSLKNFGDIYVS
                     ALAILQSAMQFASVPLTGFAQGFVPIISYNYGHGDKQRVKDCFRIVLIVMFSFNLILM
                     LFMILFPSTVASAFTSDKELIDTVRWVMPIFLAGMTIFGLQRACQNMFVALGQAKISI
                     FIALLRKVILLIPLALLLPHFMGVTGVYAAEAVSDATAAICCTLLFIWKFPKILGKIK
                     QKEERAAQ"
BASE COUNT         1444 a         1072 c         1251 g         1407 t
ORIGIN      
        1 ctgaaagcgg gtggtacggt gaaatacgga gacgtgactt ctttccaaaa cgagaatcgt
       61 ctggcctcat tcatgggtcg tttcaattat atgtatgaca accgttttat cgctaccgtg
      121 aacttacgtg cggacggttc ctctaaattg ggtatgaata ataaatgggg cttcttccct
      181 tccgcttccg ccgcttgggt gttgaatgag gaggctttct tgaaagacgt ggattggctg
      241 agccagttga aactacgtgc gggttatggc ctgaccggta accaagatgc tatcgaggct
      301 tataactcgt tggctttgat gagcccgaac ggcgtgactt ccgtcaatgg aaattctacc
      361 gctacctatg gctttacacg taactcgaac ccggacttgc gttgggaggt gaaaaagaca
      421 ttcgatgtgg gtgtggacgc tggtattctc gatggccgct ttacgttgac cgccgattgg
      481 tatacttcca agactacgga tctgttgtat aaatatgcgg ttccggttcc tccgttcgta
      541 tatccggaat tattggcgaa cttgggagag atgaccaact ccggcgtgga attggctgta
      601 agcggtggta tcgtgaagac aaaggatttc gatttcaaca tgggcgtgaa tttctcttac
      661 cagaagaata aattgaactc cttgagcggt tcttatatgg gacaagagtt gcaggcgaaa
      721 caatatatgg atctgtccag tatgagtggt gccggtttcg taggaaacaa ccgtgtggtt
      781 tatcagatgg taggccagcc tgtcggagtg ttctacattc ctcgttgctt gggcttgact
      841 ccggctttgg atgagaatgg aaacgctatc gaaggccgct atatctacaa cttggatcag
      901 acgatcgatg gaaaagaggg tttggatacc aatgatggtg gcgaccgtta tatcgccgga
      961 caagccatgc cgaaatatta tctgggaatg aacttcagct tccgctacaa acgctttgac
     1021 ttgatgacgc agatgaacgg cgctttcggt cataagatct tcaacggtac atcgctagct
     1081 tatatgaact tgagccagtt ccctacatac aacgcgttgg ctaaggctcc ggaaagcaag
     1141 atctacgacc agtcgatctc tgattattgg ttggaaaagg gcaattattt gaatatcgat
     1201 tatattacgt tgggttacaa catcgattgc aagaagatcg agaaatacgt gaagaatatc
     1261 cgtgtgacat tctcggtgaa caacgtggct acgatcacgg gttactccgg cttgtctccg
     1321 atgattaaca gtacgacggt cgataaagat aataatgacc taggtatgga taacaaacgt
     1381 ttctatccgt tatcccgtac gtattcatta ggtttgagtg ttaacttcta aatccattta
     1441 aagagtcatg aaaaagaaat ttatatatag ctttatgata gccgctgccg ccgcggcatt
     1501 ttcttcctgt tctaattttt tggaagagcg tcctacagac gcgtttgatg aggagaccgc
     1561 gttccaaagc cctacgttgg tctatgtaaa cacggttgcg agcctgtaca ataatatgtt
     1621 caagatcatg ggtaacgacc gtcatgtata tgacttgaat accttctcca gcgatgaggc
     1681 tatgcttcct tgccgtatcg gcgactggga agatggcggt ttatggcaga atattttctt
     1741 acaccgttgg ggcacgatga atgatttgac caagaactct tgggatttct tgtatgagca
     1801 gatcggaaaa tgcaaccaga gtgttgataa gttgcaagcc tttgccgagg aacaaccgga
     1861 cgtggaatat ttcaaggttt atctggaaga ggtccgtgcg gtccgtgcgt ttttctatta
     1921 tgagttgttg gatttgttcg ctcgtgttcc gttggtaact tcctctacga caccgatgtc
     1981 tgaggtaaag caatctgagc gtagcgttgt atttaacttt gtccgttcgg agttggagga
     2041 ggcgttgcct tatctttcag ataaccgcag taaccaaaaa ggtgagtatt acggacgtat
     2101 taccaagccg gtggcttata tgatcttggc taagttggcg ttgaacgcgg aggtttatgc
     2161 ggacgacaat tggacggacg gcaatcgtcc ggatggaaag aacatcaagt ttaccgttga
     2221 cggtaaagag atgaacgctt gggaagcaac gatcgcctat gtggataagt tggaggcttt
     2281 gggctataag ttgcagggaa acttctcgga gaatttcgcc gtagcgaacg agacctcggt
     2341 tgagaatatt ttcacggttc ctatggaccc ggtcgcttat ccggacgcta aggactataa
     2401 cgtggtacgt acccgccatt atgatcatgc tacggcttac ggccaatccg gatggaatgg
     2461 ctcttgcgct acggtgaagg cgatgaacgt gtttaagttc ggtacggcgg atgaggatcc
     2521 tcgttgtaag cttacttatt ttacgggcga ggtgaccggc ccggatggaa agacgatcta
     2581 tacggaatgg gacggacaga aagtgccttt gaaatatgag ccgaacgccc cgaaggtata
     2641 tatggatgcc tccgatggtt tgttggtgaa gaccgccgga gctcgtatgg ctaaatatga
     2701 gttcgaccag aatgctcagg atggtggaaa cttgcatgga aatgactgcg tgatcttccg
     2761 tttcgccgat gcgttgctga tgaaggcgga agccaagatt cgtctgggac agaatggaga
     2821 cgatgaggtg aaccaagttc gcaaccgtgt aggcgccaaa ccgctacaaa acgtaacgct
     2881 ggatacgcta ttagacgagc gtatgcttga attagcgtgg gaaggcgtac gccggcagga
     2941 tttgatccgt ttcggtaagt ttaccgaggc tacggtagac cgttatgtag gcgtgaaaca
     3001 ttccgccagc tcactggatt atcaagagga taagacggga tatacaacgg tattctccat
     3061 ctatgccgat atccttagcc tgaatcctaa cttgacacag aatccgggat attaatacga
     3121 ttcattttaa tctttaaggc tttatcaggg ggctgtccgt tattgggcag ccctttcttc
     3181 tttttgcttg attttcccta gtatcttcgg gaatttccat ataaataaca acgtacagca
     3241 aatagcggcc gtggcatccg atacggcttc tgccgcgtat acgccggtta cccccataaa
     3301 atgaggtaat agtaatgcca aaggaatcaa gaggattact ttacgaagca aggcgataaa
     3361 gatagatatc ttagcttgtc ccaacgctac gaacatattc tggcaagctc gttgtaagcc
     3421 aaaaatcgtc atacccgcca agaagatggg catgacccaa cggacggtat cgatcaactc
     3481 cttgtcgctt gtaaaagcgg aggctacggt tgaggggaat aagatcatga atagcatgag
     3541 tatcaagttg aaagagaaca taacgattag cacgatacga aaacaatctt tcacccgctg
     3601 tttgtctcca tgtccgtaat tatagcttat gatcggtacg aatccttggg cgaaaccggt
     3661 cagcggtacg ctggcgaatt gcatggcact ctgtaagata gccaatgcgc tcacatagat
     3721 atcgccaaaa tttttcaaac tactattcaa gacgaaacct accagactct ccgtgctggc
     3781 catgatgaac ggagaaattc ccaaagcgaa catcgagagt acgattcttc ggtccagtct
     3841 catataccgc ctttccaaag gcaaggaggc acgtcttgag aaaaggaagc tcaataccca
     3901 tatggcactg caagcttgtg ataggatcgt ggcgagcgcg gcgcctttta cccccatatc
     3961 caaccagaaa atgaagatag ggtctaatac gatattcaat aaagccccga tcaaaaccga
     4021 gcacatagcg atagacggac gcccttgtgc gttgataaag gcattcaagc ccgtggatat
     4081 ctcgacaaac agagtgccca gtaaataaat agagagataa tccaccgcat atcctaacgt
     4141 atattttgat gctcctgtaa aaagcaggat cggttccatg aaggtatagg tgatgaggga
     4201 agtgaatata gtaaatagga taagcaatat aaatccattt cccactattt ttccggcccg
     4261 ttcccggtcg ccctgcccga gagcgatagc cgctaacggc gaaccgcccg ctcccacgat
     4321 agcggagaaa gaagagatca agatcacgat ggaggtggtc acccctatac cagccaaagc
     4381 gtttgtcccg atctcgggaa tatgcccgat atagatacga tctacgatat tgtaaagtag
     4441 gttgacaaat tgggccgcta ccgccggaag cgccattttg aaaaccagcg gtagcatacg
     4501 ttccgtacct agcctagcct cgtatttgtt cttcatattc aatcgggatt tcaattaaaa
     4561 tggctgcaaa gttacaagaa cttgttggat tatataatcg agttccataa attaccagtt
     4621 aataaaaaac acttaatatc taccacatct acaattcctt cttatatgcc ttataaataa
     4681 acatcttata tagtggttgt agatagaaaa tatctacaat tatcattctt tatctaccat
     4741 gttttgatag aaaacgcaag aaaccaaatt atcgtttagg ttcgtgtgtc gtagtgccta
     4801 tatatgtaaa agtagtttct attagggaaa acaaaagttt cgtgctgaag aaactttagt
     4861 ttctatatag ggaaacaaaa gttttctgat tgataaactt ttgtttttta ccataaaaaa
     4921 ctgcaaatgc ttatatgcta atattttaaa tacataatat aactagtaga tacatagtgt
     4981 gccgcatctc cttgctggct gatcgtatct caaaatcact attgaaaaac aaatatttta
     5041 gtggtattta taaaataaat tttataactt gcgtttaagt tgtaaactgt aatctaaatg
     5101 aagagaacac taggactgac tttgctactt ttcgctaccc ttttttcttg tatgcgccaa
     5161 gaaaaaccat tacc
//
LOCUS       DBMDTB010000163         5154 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_3932_length_5154_cov_12.952701, whole genome shotgun sequence.
ACCESSION   DBMDTB010000163 DBMDTB010000000
VERSION     DBMDTB010000163.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 5154)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 5154)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5154
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_3932_length_5154_cov_12.952701"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..209)
                     /locus_tag="ACZPB4_16230"
     CDS             complement(<1..209)
                     /locus_tag="ACZPB4_16230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HIR1099798.1"
                     /translation="MEIYLIRHTSVDVPAGYAYGQTDVPLKPTFEEEAEEVKKGLSDH
                     TFDKVWTSPLTRCVRLANYCGFPEA"
     gene            complement(212..961)
                     /locus_tag="ACZPB4_16235"
     CDS             complement(212..961)
                     /locus_tag="ACZPB4_16235"
                     /EC_number="2.7.8.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008818 - cobalamin 5'-phosphate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0051073 - adenosylcobinamide-GDP
                     ribazoletransferase activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide-GDP ribazoletransferase"
                     /protein_id="HIR1099799.1"
                     /translation="MLRILAAFIFFTRLPFWRLAEVPAACFKNIVSHWALVGWLTAGL
                     SVLVLYATSLILPPSVAILCAMITRLLITGCLHEDGLADFFDGFGGGTSRERILAIMK
                     DSHIGSYGVIGLIFYFGLFYLLVSSLPIELAGCAILAGDPFCKGVSSMIINRLPYARK
                     EEEAKNKTVYSRMTSREYVFSIICAFLPLLWLPQPVYLLAGIFPVITWYFLTSFMKRK
                     IQGYTGDCCGATFLLSELSFYMGFVIIYQTI"
     gene            complement(963..2003)
                     /gene="cobT"
                     /locus_tag="ACZPB4_16240"
     CDS             complement(963..2003)
                     /gene="cobT"
                     /locus_tag="ACZPB4_16240"
                     /EC_number="2.4.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016273665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008939 -
                     nicotinate-nucleotide-dimethylbenzimidazole
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide--dimethylbenzimidazole
                     phosphoribosyltransferase"
                     /protein_id="HIR1099800.1"
                     /translation="MIQFHIEAPDKGLEAALQDKIDNLTKPKGSLGTLEALALQVGLI
                     QQTLSPVLRHPVNVIYASDHGIADEGVSKSPKEVTRQVIHNFLNGGAGVCYLARQHGF
                     ELKIVDGGVDFDFPVIPQLIDRKVRKGGTRNFLHEAAMTVEEMEKALQYGADIVTDCY
                     NEGCNVISFGEMGIGNTAASSMWMTCLTQIPLIDCVGAGSGLDSEGVRHKYNVLKRSL
                     ENYKGDGSALDVMRYFGGYEMVMAVGGMLRAAELKMIILVDGFIMTNCVLVASRLYPE
                     MQSYCVFGHCGDEAGHKRVLDFLGAKALLDLGLRLGEGSGSVCAYPILDSAVRMINEM
                     HSFKQAAITKYF"
     gene            complement(2034..2549)
                     /locus_tag="ACZPB4_16245"
     CDS             complement(2034..2549)
                     /locus_tag="ACZPB4_16245"
                     /EC_number="2.7.1.156"
                     /EC_number="2.7.7.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0008820 - cobinamide phosphate
                     guanylyltransferase activity [Evidence IEA];
                     GO_function: GO:0043752 - adenosylcobinamide kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional adenosylcobinamide
                     kinase/adenosylcobinamide-phosphate guanylyltransferase"
                     /protein_id="HIR1099801.1"
                     /translation="MSKKVILVTGGQRSGKSGYAQRLALSLSPNPVYLATSRIWDEEF
                     RKRVERHQRDRGPEWTNIEEEKYLSRHDLTDRVVVIDCVTLWGTNFFFDNQSDVELSL
                     SLLKAEFDKLSRQDAYLIFVTNELGMGGVPIDEVQRKFTDMQGWLNQYIASKADEVVL
                     MVSGIPVKIKE"
     gene            complement(2542..3111)
                     /locus_tag="ACZPB4_16250"
     CDS             complement(2542..3111)
                     /locus_tag="ACZPB4_16250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein"
                     /protein_id="HIR1099802.1"
                     /translation="MEIRLNKLISEAGVCSRREADNFIEMERVTVNGKQPHVGQKVTA
                     EDVVLVDGERLNVEKYIRLQEEEKKEMQQEKELLGTLRKAKPENKGGREGAKMEKFGK
                     FNKYAAARKAQKEGGWKSKTAKLTDEEKLLRDALRPKFGKALSKSAVAQRIAANPKSA
                     ALRKTSKNNPINKAKRAAHRKNRNHGGDE"
     gene            complement(3122..4081)
                     /gene="cbiB"
                     /locus_tag="ACZPB4_16255"
     CDS             complement(3122..4081)
                     /gene="cbiB"
                     /locus_tag="ACZPB4_16255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0048472 - threonine-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide-phosphate synthase CbiB"
                     /protein_id="HIR1099803.1"
                     /translation="MTFNMYWLHHSINLLKIVPFLGGWLSDRLLGDPEGWPHPIVWFG
                     KAISAGEKALNKGSERALKGGILAVVLILGVYLICEWILSWAWIIHPQFSGLLTAVGV
                     FYCLSGKTLIKEVKAVFEAVDRSTEEGRRQVARIVGRDTSNLSPQEIRAAALETLSEN
                     LSDGVIAPMFWFALLGLPGMMAYKMVNTLDSMIGYKNERYLEFGRIAALIDDIANYIP
                     ARLTAYLMLLVSNNWGKRDFVRRFGPEHASPNSGYPEAALAAVLDCQFGGTHDYFGKP
                     VEKPYIGTNARPFTTEDMRIAIQVNSNTELVMGVIVTLILLII"
     gene            4462..5016
                     /locus_tag="ACZPB4_16260"
     CDS             4462..5016
                     /locus_tag="ACZPB4_16260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012056240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma-70 factor"
                     /protein_id="HIR1099804.1"
                     /translation="MTDEKSILEQFAVGNHTAFRELFMRYHLKVYYFVLGLVKSESDA
                     EDLTQEIFLKLWTHRSRFTEVRTFGSYLYVLAKHTAFNYIESRRVNLVSLERAGEEDG
                     ERSDTPYEDLVAKDLRLLVDMIVETMPPQRKMIYRMSRDEGLSNTEIAENLQLSKKTV
                     ENHLNLALKELRNAVLTFLLVMMC"
BASE COUNT         1280 a         1372 c         1207 g         1295 t
ORIGIN      
        1 tccgcctccg gaaagccgca ataattagct aagcgcacgc agcgggtaag gggacttgtc
       61 caaaccttat cgaacgtatg atcgctcaag ccttttttta cctcttccgc ctcttcctcg
      121 aaggtcggtt tcaatggaac atcggtttgc ccgtaggcgt agccggcggg aacatcgaca
      181 gaggtatgtc tgattaaata aatctccata attatatagt ttgatagatg atcacgaaac
      241 ccatatagaa gcttaactca ctaagaagaa aagtcgctcc acagcagtct cccgtatatc
      301 cttgtatctt tctcttcatg aaagaggtaa ggaaatacca agtgataacc gggaatatac
      361 ccgctagtaa gtaaacaggt tggggaagcc ataataatgg taagaaagca caaatgatgc
      421 taaatacata ttctcgagag gtcattcggc tatatacggt cttgttcttg gcttcctcct
      481 ctttcctcgc gtaaggcagg cgattgatga tcatgctgga gacgcctttg caaaaaggat
      541 ctccagccag tatggcacat cccgctagct cgatcgggag actgcttact agtaggtaga
      601 atagtccgaa gtagaaaatc agtccgatta ccccatagct acctatatgc gagtctttca
      661 tgatcgccaa tatgcgttcc cggctcgtgc cgccgccgaa accgtcgaag aaatccgcca
      721 gcccgtcctc atgcaggcag ccggttatca gcaatcgggt aatcatggcg cataagatcg
      781 ccacggatgg cggaagaatc aaggaggtag cgtacaatac caataccgac aaaccagccg
      841 tcagccaacc gaccaacgcc caatggctca cgatattctt gaaacaggcc gccggaacct
      901 ccgccaaccg ccagaacggt aaccgagtaa agaatataaa cgcagcgagt atccgcaaca
      961 tatcagaaat atttggtgat tgccgcttgc ttgaaactat gcatctcgtt gatcatgcga
     1021 acggcggagt cgagtatcgg gtaagcgcat accgagccgg aaccttctcc cagccgtagc
     1081 cctagatcga gcaatgcttt cgcccccaag aaatccagta cccgtttatg cccggcctcg
     1141 tcgccgcaat gcccgaatac gcaatacgat tgcatctccg gatataagcg ggaagccacc
     1201 aatacgcaat tcgtcatgat aaaaccatcc acgaggataa tcatcttcag ttcggcggca
     1261 cgcaacatgc ctcctacagc cataaccatc tcataccctc cgaagtagcg cattacatcc
     1321 aaggcgcttc catccccctt ataattctcc aacgagcgtt tcagtacgtt gtatttatgc
     1381 cgtacgccct cgctgtccag tccactaccg gcccccacac agtcgatcaa tgggatttgt
     1441 gtgaggcaag tcatccacat gctggaagcc gccgtattcc ctatacccat ctctccgaaa
     1501 ctgatcacgt tacagccttc gttgtaacaa tccgtcacga tatcggctcc gtattgaagg
     1561 gctttctcca tttcctccac ggtcatggcc gcctcgtgaa gaaagttacg ggttcctccc
     1621 ttgcgcacct tgcggtcgat gagttgggga ataacgggga aatcgaaatc cacgccgcca
     1681 tccacgatct tcaactcaaa accatgctgg cgggcaaggt aacaaactcc cgctcctccg
     1741 ttcaagaaat tatggatcac ttggcgagtt acctcctttg gagatttact tacgccctcg
     1801 tcggcgatgc cgtgatccga tgcatagatt acgttcacgg gatgacgcaa gacaggcgat
     1861 aaggtctgct ggatcaatcc cacttgcagg gcgagcgcct cgagcgttcc caatgagcct
     1921 ttcggctttg tcagattatc gatcttgtct tgtaaagcgg cctccagccc tttgtccggg
     1981 gcctcgatgt gaaattgtat catgatagta gtattttata taagtcgttg ttcttattcc
     2041 ttgatcttga cggggattcc gctgaccatc aagacaacct cgtccgcttt agaggcaata
     2101 tattggttga gccagccttg catatcggta aatttacgtt gcacctcgtc tatcggcacg
     2161 cctcccatac ccagctcgtt cgtcacgaag atcaggtagg catcttgccg ggagagttta
     2221 tcgaactccg ctttgaggag ggagagagat aattccacgt cgctttgatt gtcgaagaag
     2281 aagttagtcc cccaaagggt tacgcaatcg atcaccacga cacgatcggt aagatcgtgg
     2341 cggctcaagt atttctcttc ctctatattg gtccactcgg gtccacggtc tcgctggtgg
     2401 cgttccaccc gcttccggaa ctcctcgtcc cagatgcggg aggtagctag gtaaaccggg
     2461 ttgggcgaca gcgataaggc gagcctctgt gcgtacccgc tcttgccgga ccgctgtcct
     2521 ccagtcacta agatcacttt cttactcatc gcctccgtga ttcctgtttt tccggtgggc
     2581 ggcacgtttc gccttgttga tcgggttgtt cttgctcgtc ttccgaaggg cggccgattt
     2641 cgggttggcg gcgatccgtt gcgccaccgc cgatttgctc agtgcctttc cgaacttggg
     2701 gcgtaaggca tctcgcaata acttctcctc gtcggtaagc ttggcggtct tggatttcca
     2761 gcctccctct ttctgcgcct tacgggcggc agcgtattta ttgaactttc cgaacttctc
     2821 cattttagcg ccttcacggc ctcccttgtt ctcgggtttc gctttccgga gcgtgccgag
     2881 taattctttt tcttgctgca tctccttttt ctcctcctct tgcaggcgga tatatttctc
     2941 tacgttcaag cgttcaccgt ccaccaatac gacatcctcc gccgtgacct tctggcctac
     3001 gtgcggttgc ttgccgttta cggttacccg ttccatctcg atgaaattgt ccgcttcccg
     3061 gcgtgagcaa acaccggctt cgcttatcag tttgtttaat ctaatttcca tattattaat
     3121 attatattat tagtaaaata agggtgacga tcacacccat caccagttcc gtattactat
     3181 tcacttgaat ggcgatacgc atatcctcgg tcgtgaaagg cctcgcgttc gttccgatat
     3241 aaggcttctc caccggtttg ccgaaataat cgtgcgtccc cccgaactgg cagtccaaga
     3301 ccgccgccaa ggccgcttct ggataaccgg aattagggct tgcgtgttca gggccgaaac
     3361 gccgtacgaa atcccttttc ccccaattat tggagacaag caacatcaaa taggccgtga
     3421 ggcgggccgg gatgtaattg gcgatatcgt cgattagcgc cgctatccgt ccgaactcta
     3481 ggtaacgctc attcttataa ccgatcatcg agtccagtgt attcaccatc ttgtaagcca
     3541 tcatccccgg caaccccagc agggcgaacc aaaacatcgg ggcgatcacg ccgtcgctca
     3601 ggttctcgga caaggtctcc aacgccgccg cccgtatctc ttgcggcgac aggttcgagg
     3661 tatccctccc aacgatccgc gccacttgcc gccgtccttc ttccgtgcta cggtccacgg
     3721 cctcgaacac cgccttcact tccttaataa gcgtcttccc ggataggcaa taaaatacgc
     3781 cgacagccgt cagcaaccca ctgaactgcg gatgtatgat ccaagcccac gacaatatcc
     3841 actcgcagat taaatacacg ccaaggataa gcacgactgc tagtatgccg ccttttaggg
     3901 cccgctcgga gcctttattc aacgctttct ctccggcgct gatcgctttg ccaaaccata
     3961 cgatcggatg gggccaacct tccgggtctc ccagcaaccg gtcggataac caaccaccca
     4021 aaaagggcac gatcttgagt aaattgatag aatgatgtaa ccaatacata ttgaatgtca
     4081 ttgaaggaac aaacttagac aaaaaaaaga acataaggaa gcggtaagcg attcttcatc
     4141 acacattagg cgaaagaaac ctacatttaa aggatttcga gcgtagactt tcatattcta
     4201 tcagccgtta aatgatcatc caccatctgt tgcatgatct tctaacagtt ggtggatgat
     4261 catacaacgg atggtagaag atgaataggt acggagaaaa cggctaaagg atgcctttag
     4321 aagccttaaa tcttcgggaa gggagggctt gatatacagt ggattccttt caattttgtg
     4381 tttattaaca aaaaaacgtt cttacggccg gttattatta ctttatttgc tcccaccgta
     4441 tcgtgaaagg agttaatcga gatgacagat gaaaaatcca ttttagaaca atttgccgtt
     4501 ggaaatcata ccgctttccg ggaattgttc atgcgttacc atctgaaagt ctattatttc
     4561 gtgctgggac tcgtgaagtc cgagagtgat gccgaggact tgacccaaga gattttccta
     4621 aagctttgga cgcatcggag tcgtttcacg gaagtgagga cgttcggttc ctacctctat
     4681 gtgctggcga agcatacggc gttcaattat atcgaatccc gccgggtgaa tctcgtgagc
     4741 ttagagagag ccggggagga agacggggaa cgaagtgata cgccttacga ggatttagtt
     4801 gccaaggatt tacggttgct agtggatatg atcgtggaga ccatgccgcc acagcggaag
     4861 atgatctacc ggatgagccg cgacgagggt ttgtcgaaca cagagatcgc cgagaatcta
     4921 caactctcga aaaagaccgt ggaaaaccac ttgaacctag cgctaaagga attgcggaac
     4981 gcggtattga ctttccttct tgttatgatg tgttaatagc ttgggggtaa agcgggaaaa
     5041 ggaggtccta taaacaagat aaaatagaaa agcaggaatg agtcctataa aaaagatatt
     5101 aaaatacttt ttccatcatt cgttctccgg ggagatggtg gatcgggtac atca
//
LOCUS       DBMDTB010000164         5058 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_3999_length_5058_cov_9.286464, whole genome shotgun sequence.
ACCESSION   DBMDTB010000164 DBMDTB010000000
VERSION     DBMDTB010000164.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 5058)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 5058)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5058
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_3999_length_5058_cov_9.286464"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..1017
                     /locus_tag="ACZPB4_16265"
     CDS             <1..1017
                     /locus_tag="ACZPB4_16265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor domain-containing
                     protein"
                     /protein_id="HIR1099805.1"
                     /translation="DWMANPNLKNETINSWELGLELKAFENRVGVDVAYYKKNAKDQI
                     LKIDVPSATGFKKKMINAGNIENKGVEVAFNATPYISESGFQWDTQLNWSKNINKVIS
                     LTDDTKEQILSDASVSFLKIVAHEGGAYGDIYGYAYQRDDNGNIIIGADGVPLRTDDM
                     VLLGNNQPKWMMGWSNTLSYKNFVLNFMFDMRYGGDVYMGSIRAGASSGNLEMTLDGR
                     DGMVVPGVLADGTPNTKSITAQAYWNGLSSNNVTEAYMYDATNIRLRELSLGYNFPRT
                     MLAKTPFTSARLSFVARNLFMIYSKTKGFDPEAAYTSGNAQGIEYGSMPTMRSLGFNI
                     NLAF"
     gene            1047..2711
                     /locus_tag="ACZPB4_16270"
     CDS             1047..2711
                     /locus_tag="ACZPB4_16270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SusD/RagB family nutrient-binding outer membrane
                     lipoprotein"
                     /protein_id="HIR1099806.1"
                     /translation="MKSSIKILAACSFIMLGVTSCDLTGINENPDKPTDDVNYNMNEP
                     RLASTLRGGMIIDGDVEQRLKPLQIDFYSQMLIDGGGWATKNYIQNDEWNNLTWQAYL
                     TQISSINIVIRSLMEKDKDLYANTIAFARIWRVYIHSQAADKFGPMPFPAYATVEDNP
                     PYKSVKDIYYEYFTELDEALNSFSDSAEPIFSDAGIDLVYKNDVSLWKKFGNSLRLRF
                     AVRLSEVDREKCVAEANAALTSPCGLISSKADNAYMPPKADGSWGQDYNYTMFQITWS
                     GPICMSKSFEKLVTNIGNIDWPAGVVNQTSGVAVSNVHPAKVDPRAPKMFQPGIENGD
                     WKGLVYGAKAEEANTGIYQSKQCAEMGFIIKDGAPYKSRPYDMFLSEEVDFLKAELFA
                     RNLVAGDAKAAYEAGVRASFETWGVSGDVEEYLASTEKNEAGTSAKYDDQQGAGNTAL
                     EKIITQKYIAGLPDLAQEAWNDKRRLNLPRLDVAVYRDQAVYNNSDTNILNPQNFIKR
                     MKYPMKEQLVNAAEYEKGKSMLGGKGDVVSTPIWWDKNSNYCTSSK"
     gene            2882..>5058
                     /locus_tag="ACZPB4_16275"
     CDS             2882..>5058
                     /locus_tag="ACZPB4_16275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SusC/RagA family TonB-linked outer membrane
                     protein"
                     /protein_id="HIR1099807.1"
                     /translation="MKLYIYIFILLLLCIFPLDAQQERSESYIRISAPVSLAGALDEI
                     ESQTNYSFIYDAQVINLSEKVRKPLSGRSVFEILNLLFKNTEIVYTVMNDQIILNKKE
                     AIIQMQQKLDGKVKGIVTDHKGEPIACVNVVEKGTRNGTITDMDGSFVLELPEEATLV
                     FSYIGYRSREIEYEGQLSLNVQLEDDAQILDEVVVTALGIEKKESSLPYATQLITGGE
                     LVRAKDFNFMSTLSGKMAGLQINRTSAGLGSSSRVIIRGSRSASGNNQPLYVIDGVPI
                     LSISSEQALTTIGGTADAGNRDAGDGISNLNPDDIESLSVLKGASASALYGGQAANGV
                     ILIKTKKGKAGVRNIHFSSSLTVDQAISLPKFQNEFGRMEGAETCWGDWASLPVYDPV
                     GDFFQTGITAINSLIFTAGNSHVQNYFSYANTTARGIVPKNNLSKHNFNLRESSSFFD
                     DRLILEGQVNLILQTIKGKPTAGGFYMNPLQGLYTFPRGMDMAPYKENFEVYNEKRNM
                     NVQNWYTTITDFEQNPYWLVNRTENEDKRARVLALASASFKVTDWLTLQGRGNIDYVN
                     DKYQQEIYASTSPGIAGENGRYIYYTYQTTLLYGDLMAKLNKSWDDFSLNAAIGTSIT
                     DTRTCALRLDSKTASLYYPNVFTIANINMSSSAYIEESDDARRQMQSFFAMAQLGYKE
                     SLYLDVTARNDWSSTLAFTERKSRGFFYPSVGLSWIIPKSFSMP"
BASE COUNT         1378 a          938 c         1286 g         1456 t
ORIGIN      
        1 gattggatgg caaatccaaa tttaaagaat gagacgatca actcttggga gttaggcctt
       61 gagttgaagg cgtttgagaa tagggttggt gtcgacgtag cgtattataa aaagaacgcc
      121 aaagaccaga tcttaaagat cgatgttcct tccgctacag ggttcaagaa aaagatgatc
      181 aacgccggta atattgagaa taagggtgta gaggttgcgt ttaacgctac tccttatatc
      241 tccgagagtg gtttccaatg ggatactcag ttgaactggt caaagaatat caacaaggta
      301 atttcattga cagatgatac gaaagagcag atccttagtg acgcatcagt aagtttcttg
      361 aagatcgtcg ctcacgaggg tggagcctat ggagatattt acggttacgc ttatcaacgg
      421 gatgataacg gcaacattat tatcggtgct gatggtgttc ctttgagaac ggacgatatg
      481 gtattgttgg gtaacaacca gccgaaatgg atgatgggtt ggagcaatac cttgtcatat
      541 aagaatttcg tgttgaactt catgttcgat atgcgttatg gcggtgatgt gtatatggga
      601 tctatccgtg cgggtgcttc atccggtaat ttagagatga cgttggatgg tcgtgatggt
      661 atggttgttc cgggggtatt ggccgatggt actcccaata cgaaaagcat tacggctcaa
      721 gcttattgga atggtctttc tagcaataac gtgacagagg cttatatgta cgatgcgaca
      781 aacatccgtt tacgtgagtt gagtttgggt tataatttcc cgagaacgat gttggcgaaa
      841 actccattta cttccgctcg cttgagtttc gtggctcgta acttgttcat gatttatagt
      901 aagacaaagg gattcgaccc ggaggctgct tatacatctg gtaacgctca aggtatcgag
      961 tacggttcta tgcctactat gagaagctta ggtttcaata ttaatctggc attttaatga
     1021 aacataaatc taaaaatgga attattatga aaagtagtat aaagatatta gcagcttgtt
     1081 cgtttataat gctgggtgtg actagttgcg acctgacagg tataaatgag aacccggata
     1141 agccgacaga tgatgtaaat tacaatatga acgaacctcg attggcctct acgctacgtg
     1201 gtgggatgat tatcgatggt gatgtggaac aacgcttgaa gcctttgcaa attgatttct
     1261 actctcaaat gttgatcgat ggcggtggct gggcaactaa gaattatatc caaaatgacg
     1321 agtggaacaa tttaacatgg caagcgtatc tgacacagat ttcctctatc aatatcgtga
     1381 tccgtagttt gatggaaaaa gataaggact tatatgctaa tacgatcgct ttcgctcgta
     1441 tctggcgtgt gtatatccat agccaggctg cggataagtt tggtccgatg cctttcccgg
     1501 cctatgctac cgtagaagat aatcctcctt ataaatcggt gaaggatatc tattatgaat
     1561 atttcacgga attggatgag gcgttgaata gcttcagcga tagcgctgag cctatattct
     1621 cggatgcagg tatcgacttg gtctataaga atgacgtttc tctttggaaa aaatttggaa
     1681 actccttgcg tcttcgtttc gctgttcgtc tatctgaggt ggatcgagag aaatgtgtcg
     1741 ctgaggcaaa tgccgctttg acatcccctt gtggcttgat ctcaagtaag gccgataacg
     1801 cttatatgcc tccaaaagcg gatggttctt ggggacaaga ctataactat acgatgttcc
     1861 agattacttg gagcggtccg atctgtatgt ccaagtcatt tgagaaatta gtgactaata
     1921 tcggtaatat cgattggcct gccggcgtgg taaaccagac atccggagtt gcggtatcga
     1981 atgtacatcc cgctaaggta gaccctcgtg ccccgaagat gttccagccg ggtattgaga
     2041 atggtgattg gaagggtttg gtatacggtg cgaaagccga ggaggcgaat actggtattt
     2101 atcagtctaa gcaatgtgca gagatgggct ttattattaa ggatggtgct ccgtataaat
     2161 ctcgtcctta tgacatgttc ctttctgagg aagttgattt cttgaaagct gagttgttcg
     2221 cccgtaattt ggtcgccggt gatgctaaag ctgcttacga ggcaggtgta cgtgcttcct
     2281 tcgagacttg gggtgtatcg ggtgatgttg aggagtattt ggcttccacg gaaaagaatg
     2341 aggctggtac cagtgcgaaa tatgacgatc aacaaggcgc gggcaatacg gctttagaaa
     2401 agatcatcac gcagaaatat atcgccggac ttccagattt ggcgcaggaa gcttggaatg
     2461 acaagcgtcg tttgaacttg cctcgtttgg atgtggctgt ttatcgagat caagctgtat
     2521 acaataatag tgatacaaat atcttgaatc ctcaaaattt catcaaacgt atgaaatacc
     2581 cgatgaaaga gcaattggta aatgctgctg aatatgagaa aggcaaatcc atgttaggtg
     2641 ggaaaggtga tgtggtttcg accccgattt ggtgggataa gaattccaac tattgcacat
     2701 cttctaaata aacagacaga cagattgatt atattgggct ttaacagaag ttgatggtta
     2761 ttctcgtttg gagatactta tctgcgaaga acagtactcc aaacgagaat tttttgtaat
     2821 aattgaatag tattagataa taattcttac atttacccat gataaattgt gtgtgtaaat
     2881 tatgaaatta tatatttata tcttcattct actattatta tgtatattcc cgctggacgc
     2941 ccaacaggaa cgttcggaat cctatattcg tatctccgct ccggttagct tggcaggcgc
     3001 tttggatgag atcgagagcc aaaccaatta ttcttttatt tatgacgctc aggtgatcaa
     3061 tttatcggag aaagtgcgta aacctttatc cgggcgttcg gttttcgaga tcttaaattt
     3121 attgtttaag aacacggaga tcgtctatac ggtcatgaat gaccagatca tcttgaataa
     3181 gaaagaggcg ataatccaaa tgcaacaaaa gctggatggt aaggtaaaag gtatcgtgac
     3241 cgaccacaaa ggagagccta ttgcttgcgt gaatgtggtg gagaaaggaa cgagaaacgg
     3301 tacgattacg gatatggatg gcagctttgt cttggagctt cccgaggagg ctactttggt
     3361 tttttcttat atcggttatc gttcacggga aattgagtat gaggggcaat tgtcattgaa
     3421 tgtgcagttg gaggatgacg cccagatttt ggacgaggta gtcgttacgg ctcttggtat
     3481 cgagaagaaa gaatcttcct tgccttatgc cacccagtta atcacaggtg gggaattggt
     3541 aagggccaag gattttaatt ttatgagtac gctttccgga aagatggccg gactccagat
     3601 taaccggact tccgccggtc tgggtagctc gtcccgggtg attattcgag gtagtcgttc
     3661 cgcgtccgga aataaccagc ctttgtatgt gatagacggt gtcccgatct tgagcattag
     3721 cagtgagcaa gccttgacaa cgatcggagg tacggccgat gccggcaacc gggatgcggg
     3781 agatggtatc tctaatctaa atcccgatga tatagagagt ttgagtgtct tgaaaggggc
     3841 ttcggcctct gcgttgtatg ggggacaagc ggcgaacggt gtgatcttga tcaaaacgaa
     3901 aaaaggtaag gccggggtac ggaatattca tttctcctcg tcgctgactg tcgatcaagc
     3961 gatcagtctc cccaagtttc agaatgagtt tggacggatg gaaggggcgg aaacttgttg
     4021 gggagactgg gcttctcttc cggtctatga ccctgtcggc gatttcttcc agacgggtat
     4081 taccgctatt aactcattga tatttacggc agggaatagc catgtgcaaa attatttctc
     4141 gtatgccaat acgaccgcac ggggtatcgt tcctaagaat aatttaagca agcataattt
     4201 taatctccgt gaaagttctt ctttctttga tgatcgtttg atcttggagg ggcaggtaaa
     4261 cttgatactc caaacaatca aaggaaaacc tacggccggg ggattttata tgaacccgtt
     4321 acaaggttta tacacgtttc ctagagggat ggatatggcg ccttataagg agaactttga
     4381 ggtatataac gagaaacgga atatgaacgt ccagaactgg tatactacga ttactgattt
     4441 tgagcaaaat ccttattggt tggtcaaccg tacggaaaac gaggacaaac gtgcccgtgt
     4501 gttggcgttg gcttccgcta gtttcaaggt aacagattgg cttacgttac agggccgtgg
     4561 aaatatcgat tatgtgaatg ataagtatca gcaggaaata tacgcttcta cctctccggg
     4621 tatcgccggt gagaacgggc gttacattta ttacacctac cagactacgt tgctctatgg
     4681 ggacttgatg gccaaattga ataaaagctg ggatgatttc tccttgaacg ccgctatcgg
     4741 tacgagcata acggacacac gcacctgtgc gttgaggctg gattcgaaaa cggcttcctt
     4801 gtattatccg aatgtcttta cgatcgctaa tattaacatg tcgtccagtg cctacattga
     4861 ggagtcggat gacgcgcgcc ggcaaatgca atcctttttt gctatggcgc agttgggata
     4921 taaggaaagc ctttacttag atgtgaccgc acgtaatgac tggtcatcta cccttgcgtt
     4981 tacggaacgt aaatcaagag gttttttcta tccttcagtc ggtctttctt ggattatccc
     5041 taaatccttc tcgatgcc
//
LOCUS       DBMDTB010000165         5033 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_4026_length_5033_cov_13.443633, whole genome shotgun sequence.
ACCESSION   DBMDTB010000165 DBMDTB010000000
VERSION     DBMDTB010000165.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 5033)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 5033)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5033
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_4026_length_5033_cov_13.443633"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..1868)
                     /locus_tag="ACZPB4_16280"
     CDS             complement(<1..1868)
                     /locus_tag="ACZPB4_16280"
                     /EC_number="6.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015645 - fatty acid ligase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-dependent synthetase/ligase"
                     /protein_id="HIR1099808.1"
                     /translation="MEKKTIIDLFESSVKRFPSNPFLWEKTGKRFEPTTYSEVRDLVY
                     EEGAGLISLGVRKGDNMALLSEGRNAWIIGELAMFYAGATNVPLSIKLEEANDLLFRL
                     VHADVKYIMVSGQQLKKIRAIKDQLPAVRKIIVLDEQAEYQDREMSLSEIRRMGKVYL
                     GIHPIEEFLAIGQSLGNDDYATITYTSGTTADPKGVILTHRNYTANVEQALTCVDIDD
                     TWRTLVILPLDHCFAHVVGFYIFMSKGASVATVQVGRTGMETLKNIPINIKEFKPYLI
                     LSVPALAKNFKKNIEQGIRARGKNAVRLFNLALRIGYIYNGDSDEEEGKGFRILLKPL
                     VRLFDKLLFAKVRENFGGELKFFIGGGALLDKDLQKFYYALGIPMYQGYGLSEATPII
                     STNGPRRHVFGSSGVLVRPLDLKICDMDGNVLPPGEKGEIVIRGENVMAGYWKNPAST
                     ADTVKEGWLYTGDMGYMRDGLLYVLGRFKSLLIGSDGEKYSPEGIEEALVEHSSCIDQ
                     LILYNNQSPYTTALLVPNKERLRKHLAHQNLDLTSDQGREEAIRIIQRQIDRFRKGGD
                     LSSMFPDRWLPTTFAILPEPFTEQNGMVNSTMKIVRGKVEKAYAARIAQLYTPEGK"
     gene            complement(1896..>5033)
                     /gene="mfd"
                     /locus_tag="ACZPB4_16285"
     CDS             complement(1896..>5033)
                     /gene="mfd"
                     /locus_tag="ACZPB4_16285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HIR1099809.1"
                     /translation="LTASNEVYFFPSAYRRAIKYGHVDPANEILRTEVLSRLQDPDAS
                     FVIVTYPDALAERVVAREVLKENTLKISVGEKLDNMFVSDVLDEYGFEQVDYVYEPGQ
                     YALRGSILDVFSFSNEFPYRIDFFGDEVETIRTFDVETQLSKEKLDSIYIVPEMSKNA
                     KDSTSLLGSLPRNTCIAARDLAWCKERIGSVWNDDPVVADEESFADIDQMRKKLVRGE
                     DFLREVLDFRRIHFGARPMGTADATIHFSTQTQPIYHKNFDRVSESFHKYLDEGYTLY
                     ILSDQEKQANRIRMIFEDRGDNIPFTAVNRTIHEGFADDTLRICFFTDHQLFDRFHKF
                     NLKSDKARSGKITLSLKELNQFSQGDYIVHIDHGVGQFGGLVRTEVNGKMQEAIKLIY
                     QNNDIIFVSIHSLHKLSKYKGKESGEPPKLSKLGTGAWEKMKERTKAKVKDIARDLIL
                     LYSKRKQETGFAYTPDSFMQHELEASFIYEDTPDQMKATAEVKADMESTRPMDRLICG
                     DVGFGKTEVAIRAAFKAVSDNKQVAVLVPTTVLAFQHYQTFCERLKDFPCKIDYISRA
                     RTAAQIKATLKELKEGEVNILIGTHRIVGKDVRFKDLGLLIIDEEQKFGVSVKEKLRQ
                     LKVNVDTLTMTATPIPRTLQFSLMGARDLSSITTPPPNRYPVQTEVERFNPDIIREAI
                     NFEMSRNGQVFFINNRIQNIYEMEALVRREVPDARVAVGHGQMEPEKLEKIILDFVNY
                     EYDVLIATSIVESGIDVPNANTIIINNAQQFGLSDLHQLRGRVGRSNRKAFCYLLSPP
                     LTSLTQEARRRLQAIENFSELGSGIHIAMQDLDIRGAGNMLGAEQSGFIADLGYETYQ
                     KILEEAVDELKSEEFADLYADNTEGHRDTGSEYVRETYIESDLELMFPPTYIPNDSER
                     ISLYRELDNMEEERDILAFTERLKDRFGKIPKEGKELIRIVRLRRMAKKLGMEKVILK
                     KGQMSLFLVNNPDSPYYQSEAFGKLLGFIQKHPRECNLREQNGKRSIVIKNVPTVEAA
                     CGYLQEMEKINSTNF"
BASE COUNT         1013 a         1435 c         1314 g         1271 t
ORIGIN      
        1 ttcttcccct cgggagtata gagctgggcg atacgggcgg cgtaggcttt ctctaccttg
       61 ccccggacga tcttcatggt gctgtttacc atgccgtttt gctcggtgaa aggctcgggg
      121 aggatggcga aggtggtcgg caaccaacga tccgggaaca tactagacag gtcgcctccc
      181 ttgcggaaac ggtcgatctg gcgctggatg atacggatgg cctcttctcg gccttgatcg
      241 ctcgtgaggt ccagattctg gtgggccaga tgcttcctca accgttcttt gttagggacc
      301 aacagggcgg tcgtgtacgg actctggtta ttgtacagga tcagctggtc gatgcaagag
      361 gaatgctcta ccaaggcctc ctctataccc tccggactgt atttctcccc gtcgcttccg
      421 atcagcaggc tcttgaaacg ccccaacaca taaagaagcc cgtcacgcat atatcccata
      481 tccccggtgt acagccaacc ctcctttacg gtatcggccg tcgatgccgg gttcttccag
      541 tagccggcca tcacgttctc tccccggatg acgatctcgc ctttctcccc cggaggaagt
      601 acgttgccgt ccatgtcgca gatctttagg tcgaggggcc gcaccaatac gccgctactg
      661 ccgaagacgt ggcggcgggg gccgttggtc gagatgatcg gtgtcgcctc gctcagcccg
      721 tatccttggt acatcgggat tcccaaggcg taatagaact tctgcaagtc cttatccagc
      781 aaggcgcccc ctccgataaa gaacttcagc tcgcccccga agttctcacg gacttttgcg
      841 aacaatagct tgtcgaacaa acggaccagt ggcttcaaga ggatgcggaa accttttcct
      901 tcctcctcgt cgctatcccc gttatagata taaccgatcc gtaaggctag gttgaaaagg
      961 cggacggcgt tcttgcctcg cgctcggata ccttgctcga tattcttctt gaagttcttc
     1021 gccaaggcgg ggacgctcag tatcaggtac ggcttgaact cctttatatt gatagggata
     1081 ttcttcaagg tctccatacc ggtacgccct acctgcacgg tagctaccga ggctcccttc
     1141 gacatgaaga tgtagaatcc taccacgtgg gcgaagcaat ggtccagcgg gagtatcacc
     1201 aacgtacgcc acgtatcgtc tatatccacg caagtgagcg cttgctccac gttcgccgta
     1261 tagttacggt gggtgaggat cacgcctttc ggatcggcgg tcgtgccgga ggtataggtg
     1321 atggtggcgt aatcatcgtt gcccagcgat tgcccgatcg ccaagaactc ctctatcgga
     1381 tgaataccca gatagacctt ccccatccgg cgtatctcgg acagcgacat ctcacggtct
     1441 tggtattccg cctgctcgtc gagtacgatg atcttccgta cggcggggag ctgatccttg
     1501 atcgcccgga ttttcttgag ttgctggccc gataccatga tatatttcac gtcggcatgg
     1561 acgaggcgga ataagaggtc gttcgcctcc tccagcttga tcgatagggg cacgttcgtc
     1621 gccccggcgt agaacatggc cagctcgccg atgatccacg cgttgcgccc ttcgctcagt
     1681 aaagccatat tatccccctt tcgcacaccc agcgatatga ggcccgcgcc ttcctcatag
     1741 acgaggtcgc gaacctcgga gtaagtggtt ggctcgaatc gcttgcccgt cttctcccat
     1801 aaaaaaggat tactggggaa gcgcttcact gaactctcaa aaaggtctat aatcgttttc
     1861 ttttccatat cttttcgtgt ttgtaagagg atgtgtcaaa agttggttga gtttattttt
     1921 tccatctctt gcaggtagcc gcatgccgct tccaccgtag ggacgttctt gatcacgata
     1981 cttcgcttgc cattctgctc ccggaggttg cattcacggg gatgcttttg gatgaagccc
     2041 agcagcttgc cgaacgcctc gctttggtaa tacgggctgt ccgggttatt caccaagaag
     2101 aggctcatct gccctttctt caggatcacc ttctccatac ccagtttctt ggccatgcga
     2161 cggaggcgca cgatccggat caactccttg ccctccttcg gtatcttgcc gaagcggtct
     2221 ttcaggcgct ccgtaaaggc gaggatgtca cgttcctcct ccatattatc caactcccgg
     2281 tatagggaaa tacgttccga gtcgttgggg atgtaggtgg gagggaacat caattccaga
     2341 tcgctctcga tataggtctc ccggacgtac tcgctacccg tatcccggtg cccttcggtg
     2401 ttatcggcgt aaagatcggc gaattcctcg cttttcaact cgtctaccgc ctcctccaag
     2461 atcttctggt acgtctcgta acccagatcc gctatgaaac cgctttgctc ggcgcctagc
     2521 atattcccgg ccccccggat gtcgaggtct tgcatggcga tatggatacc gctacccagc
     2581 tcggagaagt tctcgatcgc ctgcaacctg cgtcgtgcct cctgcgtcag cgaggtgagg
     2641 ggcggggaaa ggaggtagca gaaggctttc cggttgcttc gtcctacacg tccgcgtagc
     2701 tgatggaggt cgctaagccc gaattgctgg gcgttgttga tgatgatggt gttggcgttg
     2761 ggcacgtcga tgccgctctc cacgatactg gtggctatca atacgtcata ctcataattc
     2821 acgaaatcga ggatgatctt ttctagcttc tccggttcca tctgcccgtg ccccacggct
     2881 acccgtgcgt cggggacttc tcgccgtacc aaggcttcca tctcgtaaat gttctggata
     2941 cggttgttga tgaagaacac ctgcccgttc cggctcatct cgaaattgat cgcttcccgg
     3001 atgatatcgg ggttgaaacg ctccacctcc gtctgcacgg gataacggtt gggcggtggc
     3061 gtggtgatgc tggaaagatc ccgggccccc atcaaggaga actgtagggt acgggggatc
     3121 ggggtggccg tcattgtcaa ggtgtccacg ttcaccttca gctgccgaag cttctccttg
     3181 acggataccc cgaacttctg ctcctcgtcg atgataagca agcccagatc cttgaaacgt
     3241 acatccttgc cgacgatccg gtgggtgccg atcaagatat tcacctcgcc ctctttcagc
     3301 tctttcaagg tagccttgat ttgcgcggcc gtacgggccc ggctgatata atcgatcttg
     3361 caagggaaat ccttcaagcg ctcacaaaac gtctggtaat gctggaaagc cagtacggtg
     3421 gtgggtacca acacggccac ctgcttattg tccgataccg ccttgaatgc cgcgcggata
     3481 gctacctcgg tctttccgaa accaacgtct ccacaaatca atcggtccat tggacgggta
     3541 ctttccatat ccgccttgac ctcggcggta gccttcatct ggtccggcgt gtcctcatag
     3601 atgaagctgg cttccagctc atgctgcatg aagctgtccg gcgtataggc gaaacccgtc
     3661 tcttgcttac gtttggaata gaggaggatc aagtcccggg cgatatcctt caccttcgcc
     3721 ttggtacgtt ccttcatctt ttcccaagcg cctgtgccga gcttgctcaa cttaggcggc
     3781 tcgccgctct ctttcccctt gtatttcgat aatttatgca gggaatggat gctgacgaat
     3841 ataatatcgt tattctgata aatcaatttg atggcctctt gcatcttacc gttcacctcg
     3901 gtgcgtacca atcccccgaa ctgtcctacg ccatggtcga tatgtacgat ataatcccct
     3961 tgcgagaact ggttcagttc cttgagcgaa agggtgatct ttccgcttcg tgccttatcg
     4021 ctcttcaagt tgaacttgtg gaagcggtcg aacaattgat gatcggtgaa aaagcagatg
     4081 cgtagcgtat catcggcgaa tccctcgtgt atcgtgcggt ttacggcggt gaaagggata
     4141 ttgtcgcccc tatcctcgaa aatcatccgg atacggttgg cttgtttctc ttgatcgctc
     4201 aatatatata atgtatagcc ctcgtcgagg tatttatgga acgactcgct cacccggtcg
     4261 aaattcttat gatagatcgg ctgcgtttgc gtagagaaat ggatggtagc gtccgccgtt
     4321 cccatcggcc gtgccccgaa atgaatgcga cggaaatcca agacctcccg taggaagtcc
     4381 tcgccccgga ctaatttctt ccgcatctgg tcgatatcgg cgaaggattc ctcgtcggct
     4441 accaccggat cgtcgttcca tacgcttccg atgcgctcct tgcaccatgc gagatctctc
     4501 gccgctatgc aggtgttccg gggaagggag cctagcaagg aagtactatc cttggcgttc
     4561 ttgctcatct ccggtacgat atagatgctg tccagtttct ccttgctgag ctgcgtctcc
     4621 acgtcgaacg tacggatggt ctccacctcg tcgccgaaaa agtcgatacg gtagggaaac
     4681 tcgttggaga aagagaaaac gtcgaggata ctgccacgga gggcgtactg ccccggctca
     4741 tatacataat cgacctgctc gaagccatac tcgtccagca cgtcggagac aaacatatta
     4801 tccagcttct cgcccacgct gatcttcaag gtgttctcct tcaatacctc ccgggccacg
     4861 actcgttccg ccaaagcgtc cggatacgtg acgatcacga aagaggcgtc cgggtcttgc
     4921 aaccggctga gtacctcggt gcgcaggatc tcgttcgccg gatcgacatg cccgtacttg
     4981 atggccctcc ggtaagcgga tgggaagaag tatacctcat tgctggcggt aag
//
LOCUS       DBMDTB010000166         5023 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_4035_length_5023_cov_13.713734, whole genome shotgun sequence.
ACCESSION   DBMDTB010000166 DBMDTB010000000
VERSION     DBMDTB010000166.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 5023)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 5023)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5023
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_4035_length_5023_cov_13.713734"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..158)
                     /locus_tag="ACZPB4_16290"
     CDS             complement(<1..158)
                     /locus_tag="ACZPB4_16290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HIR1099810.1"
                     /translation="MKAINPNEIKDNFIELIGKEWMLVSAGDKEKFNMMTASWGGVGV
                     LWNRPVVFA"
     gene            complement(198..2525)
                     /locus_tag="ACZPB4_16295"
     CDS             complement(198..2525)
                     /locus_tag="ACZPB4_16295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane beta-barrel protein"
                     /protein_id="HIR1099811.1"
                     /translation="MKRMMIWIILLGGMVQGAFAQNLEIKGMVRDARNKEILEFANVV
                     LQTMDSSFVAGTTTDMKGHFLLNKIKKGSYILSVSSLGFKTEYISLEGLSKNISLGEI
                     SLNDDAVSLDGVTVSASAQTSHADKKVVFPSERQMKASGNGMDLLQQMMLPRVQVDLL
                     NSEIKATGNGVVQVRINGVKVEQDEIKALNPSDIIRIEYHDNPGLRYGNADIVLDYIV
                     RRPDTGGSFGLDMAQGINSMWGEHNAWGKINHKNSEWGASYRIGPRDFYGMKRNNEEE
                     FHLANGTTLNRVEIGEPSRARLFMHNLNVNYSYQKPDKYMFNATFRYRNNHQPHWDYQ
                     GVLMNKANPEDKVDMIDLSGSAYQAPALDLYYQRDLKHNQTLVFNVVGTYNQTKSTRI
                     YQESKHEQLLTDVNNVVDGDKYSIIGEAIYEKKLTNGNRLSGGLRHNQSFSDNSYING
                     HNYKTHMEQMESSVYAEFKGKVKKLDYSLGVTVNRSSYSQRGEDADYERYTVSPRLTL
                     FYALPGESSIRLKSTMGNVTPSLGELSAIDQVIDSLQIQRGNPNLKSYMSYYTELNYE
                     FRKGLFYVNALGAYEYQPDAIMDEKYLEGNKIIQTWNNQKNWQRVVASVNLRVGPIKD
                     ILQFSVNGGMNHYMSNGNTYTHRYTNWWCDANVSVTWKNWSLMYMLMTNWNWFKGETM
                     SGGENIQGIQLGYRHKDLMIGLRVFNPFTDNYKQETENWNQYASFHRSNYIKESSRLF
                     VATISYNFSFGRKFSAGQKKVNNADNDSGVMSTGK"
     gene            2701..4101
                     /locus_tag="ACZPB4_16300"
     CDS             2701..4101
                     /locus_tag="ACZPB4_16300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/glycine:cation symporter family protein"
                     /protein_id="HIR1099812.1"
                     /translation="MELLNNWINGVNDILWSYILIIMLLGCAVWFTIKSRFVQFRMIG
                     EMIRLLGDSAGKGEKGEKHISSFQAFAVSLASRVGTGNLAGVATAVAIGGPGSVFWMW
                     LIALLGSSSAFVESTLAQLYKEKGKDSFIGGPAYYMLHGLGLRWMGVLFAVLISITFG
                     FAFNSVQSNTICAAWEGAFGIDHAWIGAILTVLTLIVIFGGIQRIARVSSIVVPVMAL
                     GYIALALGIVLFNITRLPAVIETILSNAFGWEQAIGGSVGAALMQGIKRGLFSNEAGM
                     GSAPNVAATAHVSHPVKQGLIQALGVFTDTLIICTCTAFIILFSGAPLDGSINGVQLT
                     QQALSNEVGSIGSTFVALAILLFAFSSIIGNYYYGEANIRFITSKRSVLFIYRILVGG
                     MVMFGALASLDLAWSLADVTMGLMTICNLIAISLLSRQAFLLLQDYVAQKKAGIKSPV
                     FDKNKIPELKDKAQCW"
     gene            4122..>5023
                     /locus_tag="ACZPB4_16305"
     CDS             4122..>5023
                     /locus_tag="ACZPB4_16305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008778660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyloxyacyl hydrolase"
                     /protein_id="HIR1099813.1"
                     /translation="MIKSKMISFYIAVMMIWTCTVKAQDDNKSLIHKIGFDVRPSYVA
                     PTSKFLKDDGYGNGLTLRKAASFHLKYGFQQNPNSKEGQLYPHTYQGIGISYNTFGNR
                     QEVGNPWAAYVFQSSRIAKISSRLSFDYEWNFGASFGWHPYDENNNYRNKIIGSKINA
                     YINLGFFLNAKLSRYCNLLVGADLTHYSNGNTHLPNAGLNTIGGRIGLVYTLNPIEES
                     HHEIGTARSLPANQLYLSSFWQRVSYDVILYGATRAKGVMLGDEAHIFPGQFGILGFN
                     LNPMYKFNRFLKAGISLDGQYDESA"
BASE COUNT         1351 a         1219 c         1036 g         1417 t
ORIGIN      
        1 gcaaacacca ccggacggtt ccataacact cccacgccgc cccaactggc agtcatcata
       61 ttaaacttct ccttatcacc ggcgcttacc agcatccact ccttaccaat caactcgata
      121 aagttgtctt tgatctcatt cggattaatc gctttcatat ctcattttat tttccctcaa
      181 agatataaaa tattccctta tttaccggta ctcattaccc ccgagtcatt atcggcatta
      241 ttcactttct tctgaccagc gctaaattta cggccgaaag agaagttata ggaaatcgtc
      301 gccacaaaca aacgggaact ttccttgatg taattcgaac ggtggaaaga ggcgtattgg
      361 ttccagttct cggtctcctg cttatagtta tccgtaaacg gattaaagac acgcaagcca
      421 atcatcaagt ctttatgcct ataaccaagc tggattcctt ggatattctc acccccactc
      481 atcgtctcgc ccttaaacca gttccaattc gtcatcaaca tatacatgag tgaccaattc
      541 ttccaagtaa cggaaacatt tgcgtcgcac caccagttcg tatatcgatg cgtgtaggta
      601 ttaccgttac tcatataatg gttcatacca ccattgacag aaaattgcaa gatgtccttg
      661 atcgggccga cccgcaagtt aacggaagcg acaacccgtt gccagttttt ctgattattc
      721 caagtctgga tgatcttatt cccttccaga tatttctcgt ccatgatagc gtccggctga
      781 tactcataag cgcccaaggc attcacgtaa aacagacctt tgcgaaactc gtaattcaat
      841 tccgtataat aactcatata agacttcaag ttaggattac cccgctgtat ttgcaaggaa
      901 tcgatcactt ggtcgatagc gctcagctca cccaaagaag gagtcacatt ccccatcgtt
      961 gatttcaaac ggatggaaga ttccccgggc aaagcataaa acaaggtcaa ccggggactc
     1021 accgtataac gttcataatc cgcatcctca ccccgttggc tataagacga tcgattcacg
     1081 gtcacaccca atgagtaatc cagttttttc acctttccct tgaattccgc atatacggaa
     1141 ctctccatct gttccatatg cgtcttatag ttatgcccat tgatataact gttatccgag
     1201 aaagattggt tatggcgtaa accgccgctc aaccgattac cattcgttaa tttcttttca
     1261 tagatagctt cgccgataat cgagtattta tcaccatcca ccacgttatt tacatcagtc
     1321 aacaattgtt catgtttact ctcctgatag atacgggtcg atttcgtttg gttataagtc
     1381 cctaccacgt taaacaccaa ggtctggtta tgcttcaaat cccgttggta atacaaatcc
     1441 agcgcaggag cttgataggc tgatcccgat agatcgatca tatccacttt atcctccgga
     1501 ttcgccttat tcatcaagac tccttgataa tcccaatgcg gttgatgatt attccggtag
     1561 cggaacgtgg cgttaaacat atacttatcc ggcttttgat agctatagtt cacattcagg
     1621 ttatgcatga acaaacgagc gcgcgaaggt tcgcctattt ccacacggtt caaggtcgtt
     1681 ccattcgcta aatggaactc ttcctcgtta ttccgtttca ttccatagaa atcacgagga
     1741 ccgatccgat aagaagcgcc ccattccgag ttcttatgat tgatctttcc ccaagcatta
     1801 tgttcacccc acatggaatt gataccttgc gccatgtcca gaccgaaact acctcccgta
     1861 tccggccggc gaacaatata atccagcacg atatcggcat tgccataacg caagcccggg
     1921 ttatcatgat attctatacg aatgatgtcc gagggattca aggccttgat ctcatcctgt
     1981 tccaccttca cgccattgat acgcacttgg actaccccat ttcccgtggc cttgatctca
     2041 ctgttcaaca aatccacctg cactctcggt agcatcatct gctgcaacaa atccataccg
     2101 tttcccgaag ccttcatctg gcgctccgat gggaagacca cttttttatc ggcatggctc
     2161 gtctgggcag aggcgctaac cgtcaccccg tctaaggata ccgcatcatc atttaaggat
     2221 atttctccca aagaaatatt cttggacaag ccttccaagg aaatatactc cgtcttaaag
     2281 cctagactag agacagatag aatataactc ccttttttaa tcttatttaa taaaaaatgc
     2341 cccttcatat ccgtagtcgt acccgctaca aaagaagagt ccattgtttg caataccaca
     2401 tttgcaaatt ccaagatttc tttgttgcga gcgtcccgca ccattccctt tatctctaag
     2461 ttctgagcaa aagctccctg taccataccg cctagcagta tgatccaaat catcatccgt
     2521 ttcattttta tcgtattttt tccgaatata gcagggtggc ctttcccgct tatcatttgt
     2581 ttctaactat aagacgacag ccgtttggaa aacgttacaa gaaaatgata aaaaaataat
     2641 atttcgatga atttgcttcg tagatacgta tctttgtaac caaacaacag attataaatc
     2701 atggagctat tgaataattg gatcaacgga gtcaacgata tattatggtc atacatcctt
     2761 attatcatgt tattgggatg cgccgtatgg tttacgataa aaagtaggtt cgtacaattc
     2821 cgcatgattg gcgagatgat ccgattatta ggcgattctg ccgggaaagg agaaaaaggg
     2881 gaaaagcata tctcctcttt ccaagccttc gccgtatctt tagccagccg tgtagggacc
     2941 ggaaacctag ccggtgtagc gacagccgta gcgatcggcg gacccggatc cgtattctgg
     3001 atgtggctga tcgctttatt gggttcttcc agcgcattcg tggaatctac gttagctcaa
     3061 ttatataaag aaaaagggaa agactcgttc attggcggtc ccgcttacta tatgctacat
     3121 ggtttggggt tacgatggat gggcgtatta tttgccgtat tgatttcgat aacctttggt
     3181 tttgccttta attccgtgca aagcaatacc atctgcgcag cttgggaagg cgcttttggc
     3241 atcgatcatg cttggatcgg ggcgattctt acggtactta cgttaatcgt catattcgga
     3301 ggtattcagc gcatcgcgag agtaagcagt attgtcgtac cggtcatggc attaggatat
     3361 atagcattgg cgttgggaat cgtactgttt aatattaccc gcctacccgc tgttatagaa
     3421 accattctgt caaacgcttt tggttgggaa caggcgatag gcggcagtgt cggagcggcg
     3481 ttgatgcaag ggattaaacg aggcctattc agtaatgagg ccggtatggg atcggcaccg
     3541 aacgtagcgg ctacggcgca tgtctcccat ccagtcaaac aaggattgat ccaagcatta
     3601 ggcgtattta ccgacacgct gattatctgt acctgcacgg cgttcatcat cttgtttagc
     3661 ggagcgccat tagacggctc catcaatgga gtccagctca cgcaacaagc tttgagtaac
     3721 gaggtgggta gcatcggtag tacgtttgtc gctttagcga tccttttgtt cgcgttcagt
     3781 agtattatcg gtaattacta ttacggagaa gcgaatattc gttttatcac gtccaagaga
     3841 agtgtcttat ttatttatcg tatattagtc ggtggaatgg tcatgttcgg tgcgttggct
     3901 agtttagact tggcttggag cctagcggac gtgaccatgg gactgatgac gatctgcaat
     3961 ttgatcgcga tctcattgtt gagccgtcag gcgttcctat tattacagga ttacgtagcc
     4021 caaaagaaag cgggtattaa aagccctgta ttcgataaga acaagatacc cgagttgaaa
     4081 gacaaagcgc aatgttggtg atcagacaaa cgtattgaag tatgataaaa agcaagatga
     4141 taagctttta catagcggta atgatgatat ggacctgtac ggtaaaagct caagatgata
     4201 ataaatccct aatccacaaa attggattcg acgtacgtcc ctcgtatgtc gccccgacta
     4261 gcaaattcct gaaagatgat ggctatggaa acgggcttac tttacgtaag gcggcttcat
     4321 tccatttgaa atacgggttc caacagaatc ctaactctaa ggagggccag ctctatccgc
     4381 acacttacca aggaataggc atctcttata atacctttgg caatcggcag gaagtaggta
     4441 atccttgggc ggcatatgtt ttccaaagct cccgcatcgc caagatctct tcccggttat
     4501 ccttcgatta tgaatggaat ttcggagcct cattcgggtg gcatccgtat gatgaaaaca
     4561 ataattaccg taataagatc atcggttcta agatcaatgc ctatatcaat ctgggatttt
     4621 tcctcaacgc gaaactatcc cgttattgca acctgctcgt cggggcggat ttaacgcact
     4681 actcaaacgg aaatactcat cttccgaatg cgggattgaa tacgattggc ggccggatcg
     4741 gactcgtcta cacgctcaat cctatcgagg aaagccatca tgagataggt accgcacgtt
     4801 ccttaccggc aaatcaatta tacctctcca gcttttggca acgtgtcagt tacgatgtca
     4861 tcctatatgg cgcgacccgg gcaaaaggag ttatgcttgg tgacgaggct catatctttc
     4921 caggtcagtt cggcatcctc ggattcaacc tcaacccgat gtacaaattc aaccggttcc
     4981 taaaagcagg tatctcccta gacggccaat atgacgaaag cgc
//
LOCUS       DBMDTB010000167         4946 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_4110_length_4946_cov_9.482559, whole genome shotgun sequence.
ACCESSION   DBMDTB010000167 DBMDTB010000000
VERSION     DBMDTB010000167.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 4946)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 4946)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4946
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_4110_length_4946_cov_9.482559"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..419)
                     /locus_tag="ACZPB4_16310"
     CDS             complement(<1..419)
                     /locus_tag="ACZPB4_16310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HIR1099814.1"
                     /translation="MKKKLIAFVCFLLVSLSGLPQLPVRLNERPVVLNTSTGVLKGKM
                     VTPNQESGYPVVLIIPGSGPTDMDGNSAALPGKNNSLRYLAEGLAGKGIASLRYDKRG
                     IASSASAGKDEYSMRFEDGIKDARGWIDYLSKDKRISG"
     gene            complement(546..2153)
                     /locus_tag="ACZPB4_16315"
     CDS             complement(546..2153)
                     /locus_tag="ACZPB4_16315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0019867 - outer membrane [Evidence IEA];
                     GO_function: GO:2001070 - starch binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RagB/SusD family nutrient uptake outer membrane
                     protein"
                     /protein_id="HIR1099815.1"
                     /translation="MKRLSIYMLAAGMAALSTSCSDFLDTVPKDQLAPSTTWQTEADA
                     KGFIVGCYKDLLDGNTLLYLDCGSDIGYNNFPWEGFRPWGDGSLSSSNPGQILYDYKS
                     IRKANTFLENVDKVTFSSDAVKANYVAQAKAIRAYKYFLMNWWYGGVPIISSYSSADE
                     AKVERNTEQEVRDYIAKDLDEALAGIAEAPEARGYIAKGAVLAIKMREALYYGDWQKA
                     KDAAKAIIDLKQYELDPDYTNLFKVSGVDSKEIILADQNIETLDGLGTIGQMYNNVDQ
                     GWSSIVPTQNLVDMYEMSDGLTKEESKTYDAKHPFANRDPRMAMTILYPGREWRGDVL
                     NTLDEKLQDGTVNKNFPTYTDNASKSALTWAKYLDPMDQYGDVWSSGACPIVFRYAEV
                     LLTYAEAANELSGPSDEIYGYLNQIRQRVGMGEVDKAKYGTKDKLRELIRRERTVELA
                     GEGLRRADIVRWQEDGKMLAEKVMNGDLLRVTGTINYGESEPTKRAEITGTAVIETRQ
                     FSSRNRYLPIPQTSMDKNPNLKQNPGY"
     gene            complement(2184..>4946)
                     /locus_tag="ACZPB4_16320"
     CDS             complement(2184..>4946)
                     /locus_tag="ACZPB4_16320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011965929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SusC/RagA family TonB-linked outer membrane
                     protein"
                     /protein_id="HIR1099816.1"
                     /translation="SLQEDTQKLDEVIVVGYGTQQKANLSGAVAQLDSKELTSRPISN
                     VSSGLQGMMPGVTVTSGQGRPGQDGSTIRIRGVGTLNSASPYILIDGIESGSMNDIDP
                     NDIESISVLKDASSAAIYGSKASNGVILITTKRGKTGAPRISYNGYVGASKATSMIDR
                     VSSADYARLWNRFEPGRYSDEDIRMFEDGSDPYGHPNTDWNDEAYRTGLLHKHNVSIT
                     GGAENVKYMASAGYLGQTGILPNSDRKQFNGRTNLDMQLTKKLAVRMNMSFIKNDFSD
                     PNASYYGGSSDQIIRQLNIISPMIPVKDKDGKYGQTNDGNPIAWLDSGQTVDNCNQNF
                     TGALSVDYDIIDGLKATVTGAYVNEDQRHTERVLSIPDDPASASRTTSLVERFVNWKR
                     YNFDALLNYSKNFGQHGLKVMVGYHAEKYEVSKNQMQRNNFPSNSLNDMDAGGASTQT
                     NDGLSRELAMLSYFGRINYDFAGKYLLEANFRADASSRFAPGHRWGYFPSFSGAWRIS
                     EEEFMESTHDWLSSLKIRASWGMLGNQDALNKSNPWENQYYPWMQTYNLDGNYPMGGN
                     LTTGYYQKAYRIEDLSWEKSTTWGIGLDAVINHVTFTFDYYDRKTTDIIMEVPVPTEF
                     GLDPYFDNVGSMRNRGVEVQLGYNNKWNDWSLNVMGNMAYNKNKIEDLGGVDRMTNPD
                     DGDLWRFVGKPIDSYYVYKADGFFQSDAEAQQWMDTYKGKDGYPFGQDFQAGDLRYVD
                     TNGDGKLDADDRVLSKTINPVVTFGLNLNVGYKAFDLTLNFTGAANVGRAFTKEAFGE
                     FSGSAGHPSTAWLDSWTPENTNASMPRVAESRKSPSEASNVMSDFWVINTSYLRLKTL
                     QLGYTLPKSVLNAIGLSNVRVYYSAENLFTIDSMPLNVDPETVSSRLSSYPLVMTNSF
                     GVNVTF"
BASE COUNT         1421 a         1351 c          897 g         1277 t
ORIGIN      
        1 ccggagatcc gtttgtcctt gcttaaataa tcgatccagc ctcgtgcgtc cttgatcccg
       61 tcctcgaaac gcatggaata ctcatccttt ccggccgagg cgctcgaagc gataccccgc
      121 ttatcataac gcagggaagc gatacccttc cctgccagcc cttccgccaa atatctcaag
      181 gaattattct tacccggcaa ggcggcggag ttcccgtcca tatccgtagg gccggagccg
      241 gggatgatca ataccacagg ataaccggac tcctgattgg gagttaccat cttccctttt
      301 aataccccgg tagacgtatt caacaccacc ggacgctcgt tcaaccgtac aggcaactgg
      361 ggcagaccag acaaggatac gagaagaaag caaacgaaag ctatcagttt ctttttcata
      421 acggaatcaa tttatatact taaagcacac atgagacata caatctcagt atccgccaaa
      481 tgtaactaaa aaaggggaaa acctctcggc cttccccctt ctttatctaa catctttata
      541 ggaaattaat aacccggatt ctgtttcaag ttcggattct tatccatgct tgtttgagga
      601 atcggcaagt aacggttacg agaagagaac tggcgagtct caataacagc cgtacccgtg
      661 atttccgcac gtttagtagg ctcagactcc ccataattaa tcgttcctgt aacacgtaac
      721 aaatcaccat tcatgacttt ctcggcaagc atctttccat cttcctgcca acggacgatg
      781 tccgcacggc gcaagccttc gccggccaac tctaccgtac gctcacgacg gatcaattca
      841 cgaagtttat ccttcgtccc atatttagcc ttatccactt cccccattcc tacacgctgg
      901 cggatctggt tcaaataacc atagatctca tcagaaggac cgctcagctc attcgcagcc
      961 tccgcatacg tcaatagaac ctccgcataa cggaatacga tcggacaagc tcccgaactc
     1021 caaacatctc catattgatc catcggatcc aagtatttcg cccaagtcaa agcactcttg
     1081 gaagcattat ctgtataagt cgggaagttc ttgttgacag taccatcttg aagtttctca
     1141 tccaaagtat tcaagacatc acctctccac tcacgtcccg gatataaaat ggtcatggcc
     1201 atacgagggt cgcgatttgc gaacggatgc tttgcgtcat aagtcttcga ctcttctttc
     1261 gtcaatccat ctgacatttc atacatatcc accaaattct gggtcgggac gatagaagac
     1321 caaccttggt caacattatt atacatttgc ccgatggttc ccaatccgtc caacgtctca
     1381 atattctgat ccgctaggat tatctcttta gaatccactc ccgatacctt aaaaagattc
     1441 gtataatccg gatccaactc atactgcttc aaatcaatga ttgccttagc tgcgtctttt
     1501 gccttttgcc aatcaccata atacaaagcc tcacgcatct tgatagctaa aacagcacct
     1561 ttagcgatat agccacgagc ctccggagcc tccgcgatcc cagctaaggc ctcgtctaaa
     1621 tccttagcta tataatcgcg tacctcttgt tccgtattgc gttccacttt agcctcgtcc
     1681 gcacttgaat aagaactaat aataggcaca ccaccatacc accaattcat caagaaatac
     1741 ttataagcac ggatcgcttt agcttgagcc acataattag cttttacagc gtcactagaa
     1801 aacgtcacct tgtctacatt ctccaagaat gtattcgcct tacgaatcga cttgtaatca
     1861 taaaggatct gcccaggatt agaactagac aatgacccat ccccccacgg gcggaatcct
     1921 tcccaaggga aattattata gcctatatct gagccacaat ccagataaag caacgtattt
     1981 ccatctagca aatccttata acagcctact atgaagccct tcgcatccgc ctctgtctgc
     2041 catgtggtag aaggagccaa ctgatcctta ggcaccgtat ccagaaaatc tgaacacgaa
     2101 gtagataacg cagccatacc agccgccaac atatatattg ataatcgttt cataaaatct
     2161 tctatttaaa tggtcttaac taattagaat gtcacattta cgccaaaaga atttgtcatc
     2221 actaatgggt agctagacaa acgggaacta acagtctccg ggtctacgtt caatggcata
     2281 gaatctatcg taaacaaatt ctccgcagaa taataaacac gtacattcga caaaccgata
     2341 gcgttcagca cactctttgg aagcgtatat cctaattgca atgtcttcag acgcaggtaa
     2401 ctggtattaa ttacccagaa atcagacatc acgttagaag cctcactcgg agattttcta
     2461 gactccgcta cacgcggcat acttgcattg gtattttccg gtgtccagct atccagccat
     2521 gcagtagaag gatgtccggc actacccgag aactcaccaa acgcttcttt cgtaaacgca
     2581 cggcctacat tagccgcacc ggtgaagttc aaagtcaagt caaatgcttt atagcctaca
     2641 ttcaagttca aaccaaatgt aacaactgga ttgatagtct tagacaatac acggtcatcc
     2701 gcatccagct ttccatctcc attcgtatct acataacgta aatcaccggc ttggaaatcc
     2761 tgtccgaacg ggtagccgtc ttttccttta taggtatcca tccattgctg tgcctccgcg
     2821 tcagattgga aaaagccatc agccttatat acatagtaag aatcgattgg ctttccaaca
     2881 aaacgccaca aatcaccgtc atcaggattt gtcatacggt ctacacctcc taaatcctcg
     2941 atcttgttct tattataggc catatttccc atcacattca atgaccagtc attccactta
     3001 ttgttataac ctagctgtac ctcgacacct cggttacgca tagaacccac gttatcgaaa
     3061 taaggatcca agccaaactc agtcgggacc ggtacctcca tgatgatatc cgtagtcttg
     3121 cgatcatagt aatcaaacgt gaaagtcaca tgattaataa ccgcatccaa gccaataccc
     3181 caagtcgtag atttctccca tgacaaatcc tcgatacgat aggctttctg ataatatccc
     3241 gtcgtcaagt tgcctcccat aggataatta ccatccaaat tataagtctg catccaagga
     3301 taatattggt tctcccaagg attcgattta tttaaggcgt cttgattacc taacataccc
     3361 caagaagcac gaatcttcaa actgctcaac caatcatgcg tactttccat aaactcctcc
     3421 tcgctgatac gccaagcacc ggagaaagaa gggaaatatc cccaacgatg tcccggagca
     3481 aaacgagagg aagcatccgc acggaagttt gcctctaata aatattttcc cgcaaaatca
     3541 taattaatac gcccaaaata ggaaagcatg gcaagctctc ggctcaaacc atcatttgtt
     3601 tgtgtagaag ccccaccggc atccatatca ttcaggctat tactcgggaa attattcctc
     3661 tgcatctgat tcttgctaac ctcatacttc tccgcatgat aacctaccat cactttcaag
     3721 ccatgctgac caaagttctt gctgtaattc agcaaagcat cgaaattata acgtttccaa
     3781 ttcacgaaac gttcaaccaa ggaagtggta cgagacgcag atgccggatc atccggtatg
     3841 ctcagaactc gctccgtatg acgttggtcc tcgttcacat aggcacccgt cacagtagcc
     3901 ttcagcccat caataatatc ataatcaaca gaaagtgccc ccgtaaaatt ctggttacaa
     3961 ttatccaccg tctgcccgga atccaaccat gcgatagggt taccatcgtt agtttgtccg
     4021 tatttgccat ccttatcctt gacaggaatc atcggactaa taatattcaa ttgacggata
     4081 atctggtcgg aagaaccacc ataatagcta gcattcggat ccgagaagtc attcttgatg
     4141 aaagacatgt tcatccgaac agccagtttc ttcgtcaact gcatatccag attcgtacgt
     4201 ccgttaaact gtttacgatc tgagttagga aggatacccg tctgccctaa atatccggcc
     4261 gaagccatat acttcacgtt ctccgcacct cctgtaatac taacattgtg cttatgcaac
     4321 aaacctgtcc gataagcctc atcattccag tccgtattag gatgtccgta aggatcagag
     4381 ccatcttcaa acatccggat gtcctcgtca ctataacgtc ccggctcgaa acgattccac
     4441 aaacgtgcgt aatcggctga gctgacacga tcaatcatgg aagtagcttt cgaggcaccc
     4501 acatatccgt tataagagat acgaggagca cccgtcttac cacgttttgt cgtgatcaag
     4561 ataacaccat tagaagcctt cgaaccgtaa atagcggcgg aagaagcgtc tttcaataca
     4621 gaaatactct caatatcatt cggatcgata tcattcatgg agccactctc gataccatcg
     4681 atcaagatat atgggctggc agagttcaaa gtaccgacac cacggatacg gatcgtacta
     4741 ccatcctgtc ccggacggcc ttgacccgag gtaacggtta cacccggcat cataccttga
     4801 agaccggaag acacgttgga gataggacgg cttgtcaact ccttgctatc caattgggct
     4861 accgctcccg acaagttcgc cttctgttgc gtaccataac cgacaacgat cacctcatct
     4921 aatttctggg tatcttcctg caagga
//
LOCUS       DBMDTB010000168         4935 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_4120_length_4935_cov_13.420149, whole genome shotgun sequence.
ACCESSION   DBMDTB010000168 DBMDTB010000000
VERSION     DBMDTB010000168.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 4935)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 4935)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4935
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_4120_length_4935_cov_13.420149"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..1281
                     /locus_tag="ACZPB4_16325"
     CDS             <1..1281
                     /locus_tag="ACZPB4_16325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010992007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SusC/RagA family TonB-linked outer membrane
                     protein"
                     /protein_id="HIR1099817.1"
                     /translation="DYDNRYYIAGSFRRDGSSRLAPEHRWGNFWSVSGMWHLGAEDFM
                     KAVKPVLSDVKIRASYGVNGNQPGSYYGYMGLYSYGKNYMDNPGSYESTQANPNLKWE
                     KNYNMNLGLDLAFIDRIFVTLEYYNRDTKDLLYNRPISATTGFLNYLGNLGQLNNKGV
                     ELEVRSLNISNADFNWTTVLNLTHNKNKIVALDGNLDQVVESSWFIRKIGLPFNTFYV
                     KEFAGVDPSSGNALYYKNTEDENGNLDRTLTQDVNEAQAVPYKQVDPKISGGLTNILS
                     YKWFDLAFTLSYSLGGYSFDKTGTYIETDGASEGNRNLPIYELDRWQKPGDITDIPRF
                     VLGRSDKVSGGSSRFVHSTDHLRLKNLTFGFTLPHNWTDKVLLDKVRVYFSGSNLLTW
                     AKWKQYDPEVPVSGEVFCETPPMRTFSFGVEVNF"
     gene            1315..2802
                     /locus_tag="ACZPB4_16330"
     CDS             1315..2802
                     /locus_tag="ACZPB4_16330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RagB/SusD family nutrient uptake outer membrane
                     protein"
                     /protein_id="HIR1099818.1"
                     /translation="MKWSIKYIVSALPFLFTACSGDWLDLDPSTSVTSDNAIQSLEDA
                     KTALNGIYRIASEHSYYGDNYLYYADCRGEDVQARIDKGPGRRVSPYYLFNVAADDAF
                     NITRVWNQPYIVIHQANSLIEKIDNGSVQTSDTQEIARIKAEALAMRGLALFDLTRLF
                     GMPYTLDNGASLGVPIEIKTELPTHQPSRNTVAECYNQVIKDLTEALPNLVTTKSDGH
                     QNVWSVKALLSRIYLYMNDNENALKYAQEVINNGGLYTLFTHDEYTSVWGKDFNSESL
                     FEFYFTLTEPSGGSGGEGAPMVYADNVKDWNNLVLTKDFLDLLGEDPDDVRHALCRLP
                     QKPDEDILPTGSTGHPKYLAKYPGKTGDVLTGNPQDNDLCIIRLSEIYLNAAEAAFKL
                     GKRSEALGYLNQIVSRANPNKSVSDSELSLERILKERRKELVGEGHAFFDYMRNNIPV
                     IRKGGWHLPQLPTDAQVINASDPRVALPIPQSEIDANPNIVQNKR"
     gene            complement(2857..3438)
                     /locus_tag="ACZPB4_16335"
     CDS             complement(2857..3438)
                     /locus_tag="ACZPB4_16335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF417 family protein"
                     /protein_id="HIR1099819.1"
                     /translation="MKKLNDLFYSFLQVAASTQKLGINLIRISILIIFVWIGGLKFWN
                     YEAEGIVPFVANSPFMSFFYTKSAPEYKTYKLKEGEFDQAKHEWHQENNTYGFSRGLG
                     ILIMAIGILTFLGIFSPKIGLVGAGLAIIMTFGTLSFLVTTPEVWVPNLGSGEFGFPL
                     LSGAGRLVIKDTAILAGAIVVLSDSAQRILKKK"
     gene            complement(3532..4368)
                     /locus_tag="ACZPB4_16340"
     CDS             complement(3532..4368)
                     /locus_tag="ACZPB4_16340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIR1099820.1"
                     /translation="MEYIFNTRLRGNIALTDSYHTNLALQKDNTLYKFIWVQSGSLRL
                     EIDHVPTTLVKGEIIPLTPLHHIEFKAINGEYLTLLFNSNFYCIFGHDNEVSCNGFLF
                     NGTSNVMQLKLSESQVASLRDITDSLTSEYAIKDNLQEEMLRILLKRFIILCTRIARE
                     KFSVSPEREKAFDMVRQFYVLVDNHFKEKKMVQDYANMLHRSPKTLSNLFTTCGLPSP
                     LRIIHERIEAEAKRLLLYSQKSAKEITEILGFEDQATFSRFFKKMTGESVSEYRKREK
                     QE"
     gene            complement(4488..>4935)
                     /gene="trxA"
                     /locus_tag="ACZPB4_16345"
     CDS             complement(4488..>4935)
                     /gene="trxA"
                     /locus_tag="ACZPB4_16345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HIR1099821.1"
                     /translation="VLFASLLVGMANASNGNKNNNNKTENKMTVTELTQEDFVKKVYD
                     FETNPNAWKFEGDKPAVIDFYATWCGPCKMMSPILDEISKEYEGKINVYKVNVDKEAD
                     LASVFGIRSIPSLLFVPMKKEPSMVQGAMPKNELKKLVDDILLESK"
BASE COUNT         1407 a         1198 c         1031 g         1299 t
ORIGIN      
        1 gattacgaca accggtatta tatcgccgga agtttccgtc gggatggtag ttcccgattg
       61 gcgccggagc atcgctgggg taatttctgg tcggtctcag gcatgtggca tctgggagcc
      121 gaggatttca tgaaagccgt aaagccggtg ttgagcgatg tcaagatccg tgcctcttat
      181 ggcgtgaacg gtaatcagcc gggatcttat tacggttata tgggtttata tagttacgga
      241 aagaactata tggataaccc cggttcgtat gaaagcacac aagctaatcc caatctaaaa
      301 tgggagaaga actataatat gaacctcgga ctagaccttg cgtttatcga tcgcatcttc
      361 gtaacgctcg agtattataa tcgtgacacc aaggatttgc tttacaaccg tccgatcagc
      421 gccacgaccg gattcctgaa ctatctgggt aatctggggc agttaaacaa taaaggtgtc
      481 gagctggagg ttcgttcctt gaatatctca aacgcagatt ttaattggac tacggtattg
      541 aacttgacac ataacaagaa taagatcgtg gcccttgatg gtaatctcga tcaagtggtg
      601 gaaagtagtt ggtttatccg gaaaatagga ttgccattca atacattcta tgtaaaggaa
      661 ttcgccgggg tagatccctc gagcggaaat gcgctgtatt ataaaaatac ggaagacgag
      721 aacggcaatc tagaccgcac cttgacccaa gatgtcaatg aggcgcaagc agttccttat
      781 aaacaagtag atccgaagat atccggcggc cttaccaata tcctttctta taaatggttc
      841 gacttggcct ttacgctctc ttattcattg ggcggctatt ctttcgacaa gaccggtacg
      901 tatatcgaga cagacggagc cagcgaagga aaccgcaacc tgcccatcta tgagttagac
      961 cgttggcaaa agcccggtga tatcaccgac attccccgtt tcgtattggg acgctccgac
     1021 aaagtgagcg gtggttcctc tcgcttcgta catagtacgg atcacttgcg gttaaagaac
     1081 ctgacgttcg ggtttaccct gcctcataac tggaccgata aagtcttgct ggataaagtc
     1141 cgtgtctatt tctccggcag caacttgctg acttgggcga aatggaagca atatgatccg
     1201 gaagtgcccg tatccggcga ggtattctgt gagacaccgc ccatgcgcac ctttagtttc
     1261 ggcgtggaag ttaatttcta aacacaacaa ttcattcgat aaaaaagaaa tacaatgaaa
     1321 tggtcaatta aatatatcgt aagcgctctt cctttcttat tcacggcttg ctccggagat
     1381 tggctggatc tggatccctc cacttccgtg accagcgata acgctattca gtcactggaa
     1441 gacgctaaaa ccgcattaaa tggaatctat cgcatagcat ccgagcatag ttattatgga
     1501 gacaactacc tctattatgc cgactgccgt ggcgaagacg tacaagctcg tattgacaaa
     1561 ggtcccggca gacgtgtatc tccgtactat ctgttcaacg tagccgccga cgacgctttt
     1621 aatatcacga gagtatggaa ccaaccctat atcgtgattc atcaagcgaa cagcttaatc
     1681 gagaaaatag acaacggtag cgtccaaacc tccgacacgc aagaaatcgc ccgtataaaa
     1741 gcagaggcgt tagctatgcg tggcttggcc ttattcgatt taacccgcct ctttggtatg
     1801 ccttatacac tggataatgg agcgtccttg ggtgtgccca tcgagatcaa gacggagttg
     1861 ccgactcacc aaccgtctcg caacacggta gccgaatgct acaaccaagt gatcaaagac
     1921 ctgaccgaag ccttacccaa ccttgttaca accaaatccg acggtcacca aaatgtatgg
     1981 agcgtgaaag cacttctatc tcgtatctat ttatatatga acgataacga gaacgccctt
     2041 aaatacgctc aagaagtaat caataacgga ggtctttata ccttgttcac gcacgatgag
     2101 tatacctccg tatggggaaa agacttcaat tccgaatccc tgttcgagtt ctactttacg
     2161 cttaccgagc cttccggcgg tagtggcgga gagggcgctc ccatggtata tgccgataac
     2221 gtgaaagatt ggaacaattt ggtcttgacg aaagatttct tggatttact gggtgaagac
     2281 ccggatgatg ttcgccatgc cttatgccgc ttacctcaaa aaccggacga ggatatcctt
     2341 ccaaccggtt cgaccggaca tcctaaatat ctagcgaagt atcccggaaa aacaggagat
     2401 gtattgaccg gcaatccgca agacaatgac ctatgcatca tccgtctgtc cgagatatac
     2461 ttaaatgcgg ccgaggcggc tttcaagcta ggaaaacgta gcgaggcgtt aggctacctg
     2521 aatcaaatcg taagccgagc caaccccaat aaatccgtta gcgactccga gctttcccta
     2581 gagagaatcc ttaaagaacg ccgcaaagaa ttggttggcg aaggacatgc gttctttgat
     2641 tacatgcgta acaatattcc ggtaatccgc aagggcggtt ggcatttgcc gcaattacct
     2701 accgacgcac aggtgatcaa cgcttccgat ccccgggtag cactcccgat tccgcaaagc
     2761 gagatcgacg caaacccgaa tatcgtacag aataaacggt aaccaacaag aaaaagggga
     2821 atggcattaa aaccattccc ctttttcttg tttcgcttat ttctttttca agatccgttg
     2881 cgccgaatcc gacagcacca cgatcgcacc ggccagtatc gccgtatctt ttatcaccaa
     2941 tcgcccagcc cccgataata acgggaaacc aaattccccg ctgccgagat taggtaccca
     3001 gacctccgga gtcgtgacca agaaggacaa cgtcccgaac gtcatgatta tagccaaccc
     3061 cgctcctacc aaaccgatct tcggcgagaa aatgccgagg aaagttaaga taccgatcgc
     3121 catgatcaag attcccaagc cacgagagaa gccatacgtg ttattctctt gatgccactc
     3181 atgcttcgct tgatcgaact caccctcttt taatttatac gtcttatatt cgggagcgct
     3241 ttttgtatag aagaaactca tgaaagggct gttcgccaca aacggaacga tgccttccgc
     3301 ttcataattc cagaacttca aaccgccgat ccacacaaat atgatcaaga tcgatatacg
     3361 gatcaaatta atacctagct tctgagtaga ggccgccact tgcaaaaacg agtaaaacag
     3421 gtcattcaac tttttcatct tattatttgt tttatagtat tgaacttata ccgcaaagat
     3481 cggtagaaac acctatcccg taaatggcga ttttaccgga tgagttagca attattcctg
     3541 tttctctctt ttccggtact cagagacgct ttctcccgtc attttcttga aaaaacggct
     3601 gaatgtggct tgatcctcga agcccaagat ctccgtgatt tccttcgcac tcttctggct
     3661 atataatagc aatcgtttgg cctcagcctc aattcgttca tgaatgatcc gcaacgggga
     3721 aggtaatccg caagtcgtaa aaagattgga taaggttttt ggggagcgat gcagcatatt
     3781 cgcataatct tggaccatct tcttttcttt aaaatggtta tctaccaata catagaactg
     3841 gcgaaccata tcgaacgcct tttcccgttc cgggcttacc gaaaacttct cacgtgcgat
     3901 ccgggtgcac aaaataatga aacgtttcag taagatacgc agcatctcct cttgcaaatt
     3961 atcctttatg gcgtactcac tcgttaggct gtcggtgata tcgcgcaaag aggcaacttg
     4021 ggattcgctc aatttcaatt gcatcacatt ggaagtcccg ttaaaaagaa aaccattaca
     4081 cgacacctca ttgtcatgtc cgaaaataca atagaagtta ctgttaaaca gaagggtcaa
     4141 gtactcgcca ttgatcgcct tgaactcgat atggtgcaaa ggagtcaagg gaataatctc
     4201 acctttcact aaggtagtcg gtacgtgatc gatctccagt cgcaacgaac cgctttgtac
     4261 ccaaataaac ttgtaaagcg tattatcttt ctgcaaagca aggttcgtgt gatacgaatc
     4321 ggtcaacgct atattacctc ttaagcgagt attaaaaata tattccatag atttcttccg
     4381 gattttaaga cggataaaga taacaatatt atataaacaa aaagcgaaag ttcactttat
     4441 tcccagcaaa cttccgcgtc actaatcccc aaaacacact atacgagtta tttcgactct
     4501 aataaaatat catctaccaa tttcttcaac tcattcttcg gcatagcccc ttgaaccata
     4561 ctcggttctt tcttcatcgg tacaaacaat aaagaaggaa tactacggat accgaaaaca
     4621 ctcgctaaat ccgcctcttt atcgacattc accttatata cgttgatttt accctcgtac
     4681 tctttgctaa tctcatccaa gataggagac atcatcttac aagggccaca ccaagtggca
     4741 tagaaatcga taaccgcagg tttatcaccc tcgaacttcc aagcgttcgg gtttgtctca
     4801 aagtcataca ctttctttac gaaatcttct tgtgttaatt ctgttactgt cattttattt
     4861 tctgttttat tgttattatt cttatttcca ttactagcgt tcgccattcc taccaaaaga
     4921 cttgcgaaca atacg
//
LOCUS       DBMDTB010000169         4914 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_4136_length_4914_cov_10.179306, whole genome shotgun sequence.
ACCESSION   DBMDTB010000169 DBMDTB010000000
VERSION     DBMDTB010000169.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 4914)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 4914)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4914
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_4136_length_4914_cov_10.179306"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..114
                     /locus_tag="ACZPB4_16350"
     CDS             <1..114
                     /locus_tag="ACZPB4_16350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HIR1099822.1"
                     /translation="YSLFRCSKKAFKQAIGALYKQHLITLEDGGIRLVNEK"
     gene            complement(211..1998)
                     /gene="lepA"
                     /locus_tag="ACZPB4_16355"
     CDS             complement(211..1998)
                     /gene="lepA"
                     /locus_tag="ACZPB4_16355"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008862039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor 4"
                     /protein_id="HIR1099823.1"
                     /translation="MKNIRNFCIIAHIDHGKSTLADRLLEYTKTVEGKDMQAQVLDDM
                     DLERERGITIKSHAIQMKYNYKGEEYILNLIDTPGHVDFSYEVSRSIAACEGALLIVD
                     AAQGIQAQTISNLYMAIENDLEIIPVMNKIDLPSAMPEEVEDQIVELLGCPREDILRA
                     SGKTGEGVTEILNTIVEKVPAPKGDPEAPLQCLIFDSVFNPFRGIIAYFKVVNGVIRK
                     GDHVKFIATGKEYDADEVGILKLDMCPREEIRTGDVGYIISGIKTSREVRVGDTITHV
                     SRPAKDAIAGFEEVKPMVFAGVYPIDSEDFENLRTSLEKLQLNDASLTFQPESSAALG
                     FGFRCGFLGLLHMEIVQERLDREFNMDVITTVPNVSYIVHTKKGEEIEVHNPGGLPDP
                     TLIDHIDEPFIRASVITNTTYIGPIMTLCLGKRGILLKQEYISGDRVEIHYDLPLGEI
                     VIDFYDKLKSISKGYASFDYHLHDFRPSKLAKLDILLNGEPVDALSTLTHVDNSVTFG
                     RRMCEKLKELIPRQQFDIAIQAAIGAKIIARETIKAVRKDVTAKCYGGDISRKRKLLE
                     KQKEGKKRMKQIGTVEVPQKAFLAVLKLD"
     gene            2085..4283
                     /locus_tag="ACZPB4_16360"
     CDS             2085..4283
                     /locus_tag="ACZPB4_16360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HIR1099824.1"
                     /translation="MTIQEINKAYNRIIGSLDEKELKNAFDFLQGLIAGIREYSFQDR
                     LNELQDTYKYMLRYRIEGAKDPMQDQIYNNLIASSYEFADIVKHKALSVDSPLSYYSR
                     RRMMQKELTNYDQLHKVLRNASLVKIETLTGTITEQQQIESATILLFNKIWTSNPLNK
                     EEIASIRNLLNDQELPFIIGSQIVSALMLGLQAAFDKEKLLLLFDAANLQEDEIRYRA
                     LIGILLTLYTYRKRTALYPQIADRLAALSEGFPNFTKAIRTITLRFILARETEKITRK
                     LQDEIIPEMIKLGPKISQKINLKDINPELLGNEMNPEWQNMLSNSSLGKKMEEFSELQ
                     QEGADVMHSTFVHLKHFPFFRELGNWFMPFTTEHSAFGNQLSKNQTEKDMLDSMTLAA
                     FMCNSDKYSLYFSMMQLPDQARQMMMGQFGSQASEMIQQTKEELISKRGKLEIISGQY
                     IQDLYRFFKLYPGHLDFDDIFTSALDFHNLPILQPYVSDEESLTTIAEYYLRKNYFLD
                     ALTIYNRLSDANQESDILFQKIGYCKQMNGDIQGALEAYLHADLINPDSKWVIRRIAG
                     CYRTLKQPEEALKYYHRYEAFNPDDLSIQICIGHCHLELKNYNEALKYYFKVDYLDNK
                     STKAWRPIAWCSFLTGKYDQARNYYKKIMDNQPNTQDFLNAGHTEWALQNIKGALAFY
                     KKAVEKESGDFSKFQEQFNQDIPDLLVAGIEEAEVPLMMDQLRYSLSDIF"
     gene            4325..4846
                     /locus_tag="ACZPB4_16365"
     CDS             4325..4846
                     /locus_tag="ACZPB4_16365"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIR1099825.1"
                     /translation="MKEMILETKRLLLRELKQDDFDNICKLLQDPIVMYAYEGAFSKK
                     EVQEWLDKQLRRYQNDGFGLWGMIEKGSGELIGQCGLTYQEFNGQQVPEIGYLLRAEY
                     WHKGYATEAAIACKEYAFNILNFDKVYSIIRDTNIPSQKVALRNDMREIANFIKHYRN
                     IDMLHLVFCVDKS"
BASE COUNT         1454 a         1136 c         1055 g         1269 t
ORIGIN      
        1 tattccttat tccgctgtag caagaaagct ttcaaacaag cgatcggggc actctataag
       61 caacatctta tcacgctgga agatggcggg atacggctcg tgaacgagaa gtgacccatt
      121 tatataaaaa aagtcaatgg aatccgttac agaatccatt gacttttctt tataaatcca
      181 ttgagttagc gaacggattc cattgacttt ctaatccagc ttcaatacgg ccaagaacgc
      241 tttttgcgga acttctaccg taccgatctg cttcattcgt ttctttccct ctttctgttt
      301 ttccagcaat ttacgcttac gggagatatc gcctccataa catttcgccg tcacgtcttt
      361 acggacagcc ttaattgtct cacgagcgat aatcttagcg cctatcgccg cttggatagc
      421 gatatcgaat tgctggcggg ggatcaactc tttcagtttc tcgcacatac gacgtccgaa
      481 agtaacgcta ttatccacgt gcgtcaatgt agacaaagcg tctaccggct caccgttcaa
      541 caggatatct aatttagcca acttactggg acggaaatca tgtaaatggt aatcgaaaga
      601 agcgtaccct tttgaaatac tcttcaactt atcataaaag tcgattacga tctcgcccaa
      661 cggcaagtca taatgaatct cgacacgatc acctgaaata tattcttgct taagcaggat
      721 gccacgctta cccagacaga gtgtcatgat cgggccgata taggtagtgt tcgtgatcac
      781 ggaagcacgg ataaacggct cgtcgatatg atcaatcaaa gtcgggtccg gcaagcctcc
      841 cggattatgt acctcgatct cctccccttt ctttgtatgc acgatataag aaacgttcgg
      901 tacagtagtt atcacatcca tattgaactc acgatccaaa cgctcctgaa caatctccat
      961 atgcaacaag cccaagaaac cgcaacggaa cccaaaaccc aacgcggcgg aactctccgg
     1021 ctggaaagtc aaggaagcgt cgttcaactg caatttctcc aatgaagtgc gaaggttctc
     1081 gaaatcctcg ctatcgatcg gatagacgcc agcgaagacc atcggcttca cctcctcaaa
     1141 gcctgcgatc gcgtctttag ccgggcgaga cacatgagtg atcgtatcac cgacacgcac
     1201 ctcccgggac gtcttgatac cggaaatgat atatcctacg tctcccgtcc ggatctcctc
     1261 acgggggcac atatctaatt tcaatatacc tacctcatca gcgtcatact cttttcctgt
     1321 agcgataaac ttcacatggt cacctttacg gatcacgccg tttaccacct tgaagtaagc
     1381 gataatacca cggaacggat taaagacgga gtcaaaaatc aaacactgca acggggcctc
     1441 cggatcacct ttcggggccg ggaccttctc cacgatcgta ttcaagatct cagtcactcc
     1501 ctcgcctgtc tttccgctcg cccgtaagat atcctcacga gggcagccca acagttccac
     1561 gatctggtcc tctacctcct ccggcatggc gctaggcagg tcgatcttgt tcatcaccgg
     1621 aataatctct aagtcattct ctatcgccat atataggtta gagatggttt gcgcctgaat
     1681 accttgggcc gcgtccacga tcagcaacgc accctcgcag gcggcgatag aacgggaaac
     1741 ctcatacgag aagtccacgt gtcccggagt atcgatcagg ttcagtatat attcttcacc
     1801 cttataatta tacttcatct ggatcgcatg gctcttgatc gtaataccac gctcacgctc
     1861 taaatccatg tcgtcaagga cttgagcttg catgtcttta ccttctactg tcttggtata
     1921 ctcaagcaaa cggtctgcca aggtactttt cccatggtca atatgagcaa taatacagaa
     1981 attgcggata ttcttcatct gctaaattta tttttaggta cgcgaagata ggaaatttag
     2041 cctaaatact atacttttgg cataccattt gttgttaata gtatatgaca atacaagaaa
     2101 taaataaagc atacaaccga attatcggtt cattagacga aaaggagcta aagaatgcgt
     2161 tcgattttct ccaaggttta atagcgggaa tacgtgagta ctcattccaa gacaggttga
     2221 acgagctaca agatacttat aaatatatgt tgcgataccg gatcgagggg gctaaagatc
     2281 cgatgcaaga ccagatatac aacaacttga tcgcatccag ctatgagttc gcggatatag
     2341 tgaagcacaa ggccttatcg gtagattcgc ctctctccta ttatagccgt aggcgaatga
     2401 tgcaaaagga gcttaccaac tatgaccagc tccacaaggt cttgagaaac gcctctttgg
     2461 tgaagataga gactctgacc ggaaccatca cggagcagca gcaaatcgaa tccgccacga
     2521 tcctattatt caataagatc tggacctcga atcctctcaa taaggaagaa atagcctcca
     2581 tcaggaacct attgaatgac caagagttgc cttttatcat cggtagccaa atcgtatcgg
     2641 cattaatgtt gggattgcaa gccgctttcg ataaggagaa actgctatta ttattcgatg
     2701 cggccaatct ccaagaagat gagattcgtt accgcgcgtt gatcgggatt ctcctgacgc
     2761 tctataccta taggaaacgt acggcgctat atccgcagat agcggatcga ctagcggctt
     2821 tatccgaggg atttcctaat ttcacgaaag cgatccgaac gattaccctt cgttttatcc
     2881 tagcccgtga gacagagaag atcacccgta agctacaaga cgagatcatt ccggagatga
     2941 tcaagctagg ccctaaaatc agtcaaaaga taaacttaaa ggatatcaat ccggaacttc
     3001 tcggaaacga gatgaatccg gagtggcaga atatgttatc gaacagttcc ttagggaaga
     3061 aaatggagga gttcagcgaa ctgcaacaag aaggcgcgga cgtaatgcac tctactttcg
     3121 tgcacctaaa gcatttcccc tttttccggg aactgggtaa ctggttcatg ccattcacga
     3181 ccgagcattc cgcttttggc aatcagttga gcaagaatca aacggaaaag gacatgctag
     3241 attccatgac tcttgcggca ttcatgtgta attccgataa atactcctta tatttcagta
     3301 tgatgcaatt gccggatcaa gcccgtcaaa tgatgatggg acaatttggt agccaagcct
     3361 ccgagatgat tcagcaaacg aaggaggaat tgatcagtaa acggggaaaa ctggaaatca
     3421 tatccggaca gtacatacag gacttgtatc gtttcttcaa actttatccg ggacatctgg
     3481 attttgatga catatttaca tctgcgctag actttcataa cctgccaatt ttgcagcctt
     3541 acgtcagtga tgaggaaagt ttgacaacta tagcggagta ttatctccgg aagaattact
     3601 tcctcgacgc gctcacgatc tacaatcgct tatccgacgc aaatcaagaa agtgatatct
     3661 tattccagaa aatcggttac tgcaaacaaa tgaatggcga tatacaaggc gccttggagg
     3721 cttatttaca tgcggatctt atcaatccgg atagtaaatg ggttattcgc cggatcgccg
     3781 gttgttaccg taccttaaag caaccagaag aagcgttgaa atactatcat cgttacgagg
     3841 ctttcaatcc ggatgattta tcgatccaaa tatgtatcgg ccactgccat cttgaactca
     3901 agaattataa tgaggcgctg aaatattatt tcaaggtaga ttatctggac aataaaagca
     3961 cgaaggcttg gcgtccgatc gcttggtgtt ctttcttgac cggtaaatac gatcaggccc
     4021 gtaattatta caaaaagatc atggataatc aacccaacac ccaagatttc ttgaatgcgg
     4081 gacatacgga atgggcatta cagaatatca agggagcgct tgctttttat aaaaaagccg
     4141 tggagaaaga gtccggtgat ttctcgaagt tccaagagca gttcaatcaa gatattcccg
     4201 atcttcttgt agcgggaatc gaggaggcgg aagtgccgtt gatgatggat caactccggt
     4261 attccttgag tgatatattc taactagtca tccaacaatt tgagaagaca aaaagaaata
     4321 tcgtatgaaa gagatgatat tagagacaaa gcgactccta ttaagggaat taaaacaaga
     4381 tgattttgat aatatatgta agcttttaca agatccgatt gtaatgtacg cttatgaggg
     4441 agcattcagt aaaaaagaag tacaagaatg gcttgataag caattaagga ggtatcaaaa
     4501 cgatggcttt ggcttatggg ggatgataga gaaaggcagc ggagagctta tcggtcagtg
     4561 tggtctcacc tatcaagaat tcaacggtca acaggttccg gagatcggtt atttgcttag
     4621 ggcggaatac tggcataaag gttatgctac cgaggccgcc atagcttgta aggaatacgc
     4681 cttcaatatc cttaacttcg acaaagtata ctccatcata cgggacacaa atatcccctc
     4741 tcaaaaagta gcactaagaa acgatatgag ggaaatcgca aatttcataa aacattatcg
     4801 caatatcgat atgcttcatt tagtattctg cgtggataag tcatagttat caagcggaaa
     4861 gactgggatt cgaacccagg gagcggttac ccgctcaccg catttcgagt gcgg
//
LOCUS       DBMDTB010000170         4843 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_4200_length_4843_cov_14.106284, whole genome shotgun sequence.
ACCESSION   DBMDTB010000170 DBMDTB010000000
VERSION     DBMDTB010000170.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 4843)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 4843)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4843
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_4200_length_4843_cov_14.106284"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(177..2219)
                     /locus_tag="ACZPB4_16370"
     CDS             complement(177..2219)
                     /locus_tag="ACZPB4_16370"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family metallopeptidase"
                     /protein_id="HIR1099826.1"
                     /translation="MRKRKMFPFLAAGIVALASCNTPQKEVVKIAAINPANMDTTVAA
                     GTDFYEYACGGWIKNNPLKPEYARFGTFDQLLENNQEQLRVLIEELSATPHEAGSVAG
                     KIGALYAMGLDSTKLNADGVAPIKEELAAINALATKSDVSKMVATLHKEGMAPFFALF
                     VDADEKNSAMNIVQLYQAGIGMGDRDYYLLEDEGSAKMRDAYRAYINKLFTLAGSSPE
                     QADAAVDAVMKIEKAIAEISYGREDLRDSQKNYNKLAYEDFKQIESPLDWDVYFESMG
                     LAGLKELDAKQINFYKDMNKALQNTTVDEQKYYLAFNLLSAAAPYLSDDFVDADFEFY
                     GKVMSGKQEQQPRWKRSLNTVNGALGEAVGEMYVEKYFPASSKEKMLTLVGNLQTALS
                     ERINGLEWMSDTTKAKAQEKLAAFTVKIGYPDKWRDYSGLEIKDDSYWANVRRSNIFD
                     MAYQLADVDKPVDKSRWHMNPQTVNAYYNPTTNEICFPAAILQPPFFNPDADDAVNYG
                     AIGVVIGHEMTHGFDDQGRNYDKDGNLIDWWTAEDAVRFKERADKLVDQYDQIIVIDT
                     LHANGRFTLGENIADHGGLLVAHQAYLNSLKGKETPAPIDGFTNEQRFFLGYATLWGQ
                     NIRPEEIRRRTKIDPHSLGKWRVNAALRNIAPFYAAFDIKEGDPMFMAPADRVVIW"
     gene            2402..3937
                     /locus_tag="ACZPB4_16375"
     CDS             2402..3937
                     /locus_tag="ACZPB4_16375"
                     /EC_number="3.2.1.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_function: GO:0046556 - alpha-L-arabinofuranosidase
                     activity [Evidence IEA];
                     GO_process: GO:0031222 - arabinan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HIR1099827.1"
                     /translation="MKKLIISVWAFIALPLFAQRDANIRIYLEQGNQQISKHIYGQFA
                     EHLGSCIYGGLWVGPESDIPNTQGYRTDVLNALKKLQIPNLRWPGGCFADEYHWMDGI
                     GPKENRPKMVNNNWGGTIEDNSFGTHEFLNLCELLGCEPYISGNVGSGTVEEMAKWME
                     YMTSEGDSPMANLRRKNGRDKAWKVKFFGVGNESWGCGGSMRPEYYSDLYRRYSTYCR
                     NYDSNVLFKIASGASDYDYNWTETLMKQIGGRMDGISLHYYTVGDWNNKGSATDFNTE
                     DYYWTLGKCLEIEDVVKKHIAIMDKYDPKKNIALMVDEWGTWWDVEPGTIPGHLFQQN
                     TMRDAFVAALTLHVFHKYTDRVKMANIAQIVNVLQSMILTKGKDMVLTPTYHVFEMYK
                     VHQDATFLPMDLICDKEKVRDNREVPVVSASASRDSQGKIHISLANVDPRQSENIHID
                     LQNVTIKSVNGRILTASSINDYNTFDSPEKVKPEVFKGAKVEKGKLSVSLPPMSIVVL
                     EVL"
     gene            4020..>4843
                     /locus_tag="ACZPB4_16380"
     CDS             4020..>4843
                     /locus_tag="ACZPB4_16380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005792036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family protein"
                     /protein_id="HIR1099828.1"
                     /translation="MKPTLFVLAAGMGSRYGGLKQLDGLGPNGETIMDYSIFDAIRGG
                     FGKLVFVIRKSFEKDFREKIISKYENHIPVEVVFQDLNDLPEGFTCPEGREKPWGTNH
                     AVLMGKKVINEPFAVINADDFYGRDSFAVLGKQLSEMDGKKNDYCMVGYRVGNTLSES
                     GSVARGVCATNEEGYLTGVVERTAIERIDGDIQFVDENGKKVVLEENTPVSMNMWGFT
                     PDYFEYSEEFFKEFLKANMGNLKSEYFIPLMVNKLITEGTARVKVLDTTSKWFGVT"
BASE COUNT         1385 a         1149 c         1076 g         1233 t
ORIGIN      
        1 aagtaaggcg attgatatat agtttcgcat ggtataaaat tttcatgtat aacgttctta
       61 atcaaacaaa aataagaaaa gtgcatcaga ccgccaaatc gggataaacg aaaaaaggga
      121 agtatgcctt tttgacgtga catacttccc tcatttatat aaactctgta tttgggttac
      181 cagataacta cccgatcagc cggagccata aacatcggat caccctcttt aatgtcaaaa
      241 gcggcataga acggggcaat attacgcaag gcggcgttca cacgccattt tcccaatgaa
      301 tgcgggtcga tcttggtacg acgacggatc tcctcgggac ggatattttg tccccacaac
      361 gtcgcatatc ccaagaagaa acgttgttca ttcgtgaagc catcgatcgg ggccggagtc
      421 tctttgccct tcaagctatt caaataagct tggtgagcga ccaacaaacc tccgtggtcg
      481 gcgatattct cacccaacgt aaaacgtccg ttggcatgaa gcgtatctat tacgataatc
      541 tggtcatatt gatcaaccaa tttatcagca cgctccttga aacgaacagc atcctcggca
      601 gtccaccaat cgatcaaatt accatcctta tcgtagttac gtccctgatc atcgaatcca
      661 tgcgtcatct catggccgat taccacgcca atagcgccat agttcaccgc atcatcggca
      721 tccggattaa agaatggagg ctgaaggatc gcagccggga aacagatctc attcgtagtc
      781 ggattgtaat aagcgttcac ggtctgcgga ttcatatgcc aacgagactt atcgaccggc
      841 ttatccacgt ccgccaattg ataggccata tcgaagatgt tagaacggcg gacattcgcc
      901 caataagaat cgtccttgat ctccaagcca ctataatcac gccatttgtc cggataacct
      961 attttcaccg taaaagcggc caatttctct tgcgctttcg ccttagtcgt atcgctcatc
     1021 cattccaagc cattgatccg ctcgctcaaa gcagtctgca aattccccac tagcgtcaac
     1081 atcttttcct tagaagaagc cgggaagtat ttctctacat acatctcgcc gacagcctcg
     1141 cccaacgcac cgtttaccgt attcaacgaa cgcttccaac gaggttgttg ttcctgcttt
     1201 ccggacatta cctttccata gaactcaaaa tcagcgtcta caaaatcatc acttaggtac
     1261 ggagccgccg cgctcaataa attaaacgcc aaataatatt tttgctcatc gaccgtcgta
     1321 ttctgcaaag ccttattcat atccttatag aagttgattt gcttcgcatc caactctttc
     1381 agcccagcta atcccatgga ttcaaaatat acatcccaat ccaacgggga ttctatttgc
     1441 ttgaaatcct cgtaagccaa tttattatag tttttctggg agtcacgcaa atcctcacgg
     1501 ccataagaga tctcagcgat agccttctct attttcatca cggcatccac cgccgcatcc
     1561 gcctgttccg ggcttgagcc ggccaacgta aataacttat ttatataagc cctgtaagcg
     1621 tcacgcatct tagcggaacc ttcatcttcc aacaaataat aatcccgatc gcccattccg
     1681 ataccagcct gatacagctg gacgatattc atggcactat tcttctcgtc agcgtccacg
     1741 aacaaagcga agaacggagc catgccttcc ttatgaagcg tagccaccat cttagagaca
     1801 tccgatttcg tcgccagcgc attgatagcg gccagttcct ctttgatagg agccactcca
     1861 tcggcattca acttcgtgct atccaatccc atcgcataca aagcgccgat cttcccggcg
     1921 acactacccg cctcatgggg cgtagcgcta agttcctcga tcaatacccg gagctgctct
     1981 tggttattct ctagtaattg gtcgaaagtt ccgaaacgag cgtattccgg tttcaaagga
     2041 ttattcttaa tccatccacc acaagcgtat tcataaaaat ccgtacctgc ggcaaccgtg
     2101 gtatccatat tcgcaggatt aatagcagcg atcttcacta cctctttctg aggagtgtta
     2161 caactcgcta aagcgactat cccagccgct aaaaacggaa acatttttct ctttctcatt
     2221 ttgtttagtc ttttgcctta aaaccttaca aagatacgat aaatacgcaa aagaaaaaca
     2281 tgtacgtgtt tcttttaaaa catgtacgac tttttccgaa aacacgtacg tgtttttcga
     2341 acgataaaag gatttatata ttcaagaata agtgtatctt tgccaataaa tcatttatat
     2401 catgaagaaa ctaataatca gcgtttgggc atttatcgcc cttcctttat tcgctcaacg
     2461 agacgcgaat atccgtattt atctggagca aggtaaccaa cagatcagta aacatattta
     2521 cgggcaattc gccgaacatc tagggagttg tatctacggt ggcttatggg tgggaccaga
     2581 gtccgacatc cctaataccc aaggataccg tacggatgtc ttaaacgcgt tgaagaaact
     2641 acagatcccg aacttacgtt ggccgggcgg ttgcttcgcc gacgaatatc attggatgga
     2701 tggaatcggc cccaaggaaa atcgcccgaa aatggtgaat aataactggg gagggacgat
     2761 tgaggataat agttttggaa cccatgagtt cttgaatcta tgtgagttat taggttgtga
     2821 gccttacatc agcggaaacg tgggaagcgg tacggttgag gaaatggcta aatggatgga
     2881 atacatgacc tcggaaggag acagcccaat ggccaaccta cgccggaaaa atggccggga
     2941 taaggcatgg aaagtcaagt ttttcggcgt tgggaacgag agttggggat gcgggggcag
     3001 tatgcgaccg gaatattatt ccgaccttta ccgtcgttac tctacgtatt gccgtaacta
     3061 tgatagcaat gtcttgttca agatcgccag cggtgccagc gattatgatt acaactggac
     3121 cgagacgctg atgaaacaaa tcggcggacg catggatggt atctctttac attattatac
     3181 agtaggagat tggaacaata aaggctccgc taccgatttc aacacggagg attattactg
     3241 gaccttagga aaatgccttg agatagagga tgtcgttaaa aagcatatcg ctatcatgga
     3301 taaatacgac ccgaagaaaa atatagccct catggtagac gaatggggta cttggtggga
     3361 tgtggaaccc ggtacgatcc ccggccatct gttccagcaa aacacgatgc gcgacgcttt
     3421 cgtagccgct cttaccctac atgtcttcca caaatatacg gaccgggtga aaatggccaa
     3481 tatcgcacag attgtcaatg tattgcagtc catgatcctc acgaaaggca aggacatggt
     3541 gcttacgcct acttaccatg tgttcgagat gtacaaggtt catcaagacg ctaccttttt
     3601 gccgatggat ctaatctgcg acaaggagaa agtaagagac aaccgggaag tgccggtcgt
     3661 aagcgcctcc gcatcccggg actcgcaggg taaaatccat atctcgttgg cgaacgtaga
     3721 tccccggcaa agcgagaaca tccatatcga cctgcaaaac gtaacgataa agagcgtgaa
     3781 cgggcgtatc ctgacagcgt cctccataaa cgactataac acattcgatt cgccggagaa
     3841 ggtcaagccg gaagttttca agggagccaa ggtggaaaag ggaaagttaa gcgtcagcct
     3901 tcctcccatg tcgatcgtcg tattagaagt tttataaaaa gacggacaat aacatggcaa
     3961 tgtttctata attattaact ttgcccgaag aattaaaaaa cacattaaag aaacgcatta
     4021 tgaaacctac attatttgta ttggcagccg gaatgggtag tcgttatgga ggattaaaac
     4081 aattggacgg cctaggtccc aatggcgaga ccatcatgga ctattctatt ttcgatgcta
     4141 ttcgtggcgg gttcggtaaa cttgtattcg ttatccgcaa atctttcgag aaagacttcc
     4201 gtgagaaaat catctccaaa tatgagaacc atatcccggt tgaagtcgta ttccaagact
     4261 tgaacgatct tccggagggc ttcacttgcc cggagggacg tgagaaaccg tggggaacca
     4321 accatgccgt attgatgggc aagaaggtta tcaatgagcc tttcgccgta atcaacgccg
     4381 atgatttcta cggacgtgac agcttcgccg tattaggcaa gcaattgtct gagatggatg
     4441 gcaagaagaa tgattattgc atggtaggct accgtgtagg taatacgttg agcgagagcg
     4501 gttccgtggc acgtggtgtt tgcgccacga acgaggaagg ttatctgaca ggcgtcgtgg
     4561 agcgtaccgc tatcgaacgt atcgacggag atatccagtt tgtagacgag aacggaaaga
     4621 aggtcgtatt ggaagaaaac acgccggtct ccatgaatat gtggggcttc actcccgatt
     4681 atttcgagta ttccgaggaa ttcttcaaag agttcttgaa agcgaacatg ggtaatttaa
     4741 agagtgaata tttcatcccg ttgatggtaa ataaattgat cacggaagga acagcccgtg
     4801 tgaaagtatt ggatacaacc tccaaatggt tcggcgtaac tta
//
LOCUS       DBMDTB010000171         4726 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_4331_length_4726_cov_7.666378, whole genome shotgun sequence.
ACCESSION   DBMDTB010000171 DBMDTB010000000
VERSION     DBMDTB010000171.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 4726)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 4726)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4726
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_4331_length_4726_cov_7.666378"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(165..626)
                     /locus_tag="ACZPB4_16385"
     CDS             complement(165..626)
                     /locus_tag="ACZPB4_16385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA deacylase
                     activity [Evidence IEA];
                     GO_function: GO:0002196 - Ser-tRNA(Ala) deacylase activity
                     [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanyl-tRNA editing protein"
                     /protein_id="HIR1099829.1"
                     /translation="MKQEIQLNEHNKQEYPPMHTAEHILNQTMVRMFGCPRSKNAHIE
                     RKKSKCDYLLAEEPSAEVMAEVEKKINEVIDRHLPVTIEFMPKEKAGGIVDLSKLPDD
                     ASDTLRIVRIGDYDACACIGSHVANTSEIGHFKLLNYDYADGRLRLRFKLV"
     gene            727..3042
                     /locus_tag="ACZPB4_16390"
     CDS             727..3042
                     /locus_tag="ACZPB4_16390"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1099830.1"
                     /translation="MPAKRLFGIISIIFLFVTCISCKSSTDLSEEKRILVIQSYEKHF
                     PAYEKMKEIMSSDLRKKGIHASVYSFYLDCEQYSEKQQRQKLFKKLNELSTWNPDIIL
                     VNDDQALNALISSRHPLAKSIPVVFMGVSYPNIPIIRKYPNMMGFYDKPDYKRNIELI
                     RRLVGNCIVIRVSDDTFQDNMMLADMNAQIQDICAVNNIYSLDRVRLSGKNGISISDI
                     PKIKPDTMYISTLSTKSANALIKGFGENYYNKAYLATKRDYMTISLGRLSAFPCFSVI
                     NELIGNQNGVVGGYVTVFKDEVEAAVNRVVSILKGTPPSDFPQIEESNKAYVFDYGVL
                     ERWSIDSSKLPEGAIIANMPFVVQYKYYIWAAGFILVVMLLLLFSYQRKRYIQEALHK
                     KDAQEKLKREKTFLSFALDSGNIFAFRYSKGVFEFDNRFYHYLGMPCVPMKIEEFQDA
                     IHPEELDNFLRDRNLLDSGFLSRKVTQRRCNFNKKGYEWWEFRYAQNKNEKDSVSDDE
                     AVEVSGLCLNIQRIKDTENSLIAARRKAEESDRMKLVFLANMSHEIRTPLNAIVGFSQ
                     LLNSDMPLEPEEKAEFIDLITKNSDLLLKLINDILDLSRIESGSMSFSYENLDLSKLM
                     GDIFHTHQLMMPEGVELKIRVPHEPLIIRSDHFRLTQVCTNFINNAVKFTAKGYIEIG
                     YELSADGKSILISVKDTGKGIPDDKKEKVFERFQKLDEFAQGTGLGLAICQSIVHTFH
                     GSISLESEVGVGSKFTISLPYTPGLELEERT"
     gene            complement(3039..4637)
                     /gene="nrfA"
                     /locus_tag="ACZPB4_16395"
     CDS             complement(3039..4637)
                     /gene="nrfA"
                     /locus_tag="ACZPB4_16395"
                     /EC_number="1.7.2.2"
                     /inference="COORDINATES: protein motif:HMM:NF008339.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-forming cytochrome c nitrite reductase"
                     /protein_id="HIR1099831.1"
                     /translation="MRILISSSVFGSNEIRIFSISTGRIIIIHIFAVNTKNILFKIKG
                     KHLKAHYKTSIAISLIVIIVLVILRTTVTGQDSIKFIDDTDDQPIDQQNSDSIDLRYS
                     NEYQSWKQTSDTTFRSLFNGNQQADILAEHPVMVVLWAGYAFSKDYLSPRGHMYSIED
                     LYKSLRTGSPMTPTSGPQPAACWTCKSPDIPRLLTTTDAKTLYKKKWAELGNEIVNPI
                     GCADCHEPQSMGLRVTRSFLKSAYKRNGLRIEDATEQEMRSLVCAQCHAEYYFQGEDR
                     ILTLPWDQGYTVENIEAYYDSINFTDFTHKLSRAHLIKAQHPDFELFQMGIHGQRGVS
                     CGECHMPAVGEDENRYNNHHIKSPLAMIDRTCQACHRESEETLRKDVYERQNKVYAIR
                     MRVEEELTKAHIEAKFAWDKGATESQMKNVLKLLRQAQWRWDFAVASHGAAFHAPQEV
                     TRILGSGLDKATQARIQIMKVLAQLGYTQDVPMPDISTKAKAQQYIGLDMEAEQQAKQ
                     KFLETVIPQWQEEARANKRFIEGN"
     gene            complement(4639..4712)
                     /locus_tag="ACZPB4_16400"
     tRNA            complement(4639..4712)
                     /locus_tag="ACZPB4_16400"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(4676..4678),aa:Arg,seq:acg)
BASE COUNT         1220 a          945 c         1125 g         1436 t
ORIGIN      
        1 gaacgttaaa gtcaactctt acaaatgcct ttttgccggc aaaattgaaa ttgtcaattg
       61 tttgcataac tattgtattt aatgtctgta ttaaaatgtt cctttaatcg cttgcaaact
      121 tacataaaat atttttattt gaccgtttgc gcttgcttta aattttatac caatttgaaa
      181 cgtagccgta atctcccgtc agcatagtcg taattcaaca gcttgaaatg tccgatctcg
      241 gatgtattcg ccacgtgcga tccgatacat gcgcaggcat cgtaatcgcc tatgcgtacg
      301 atacgtaatg tgtcgctggc atcatcgggc aatttactta aatccacgat accgccggcc
      361 ttttcttttg gcatgaactc gatggttacg ggcaggtgcc ggtcgatcac ctcgtttatc
      421 ttcttctcaa cctcggccat gacctccgcg ctgggctctt ccgccaatag ataatcgcat
      481 ttagacttct tcctctctat gtgtgcgttc ttggatctgg gacatccgaa catccgtacc
      541 attgtctggt ttaagatatg ttccgccgtg tgcataggag gatactcttg cttgttgtgt
      601 tcgttcagtt ggatttcttg tttcatatat ttgatgtttt gattgtattt cgtgaaaaat
      661 atgctcaaat gtacgaaata aatctttagt tttgtaaagt catagaaaac accttaaagg
      721 aacgatatgc cagctaagcg cttatttgga ataatatcca tcatatttct ctttgttacc
      781 tgtatatcat gtaaatcctc tacagactta tcggaggaga agcgtatact cgtgattcaa
      841 tcttacgaaa aacattttcc cgcctatgag aagatgaagg aaatcatgtc gagtgatttg
      901 cggaagaagg ggatacatgc gagtgtctat tctttttatt tggattgtga gcaatattcg
      961 gagaagcaac agcgacagaa attattcaag aaactgaatg agttatcgac atggaacccg
     1021 gatattattc tggtcaatga cgatcaagcc ttgaacgctt tgataagtag caggcatccc
     1081 ctcgctaaat cgatcccggt cgtgtttatg ggggttagtt atcccaatat cccgatcatc
     1141 cggaaatatc cgaatatgat gggcttttat gataaaccgg attataagag gaatatagaa
     1201 ttgatacggc ggcttgttgg taattgcatc gtcataagag tctcggacga tacctttcag
     1261 gataatatga tgctggcgga catgaatgcg cagattcagg atatttgtgc cgtgaacaat
     1321 atatattcct tggatcgggt acgtttatcc ggaaagaacg ggatttcgat atcggatata
     1381 cctaagataa agccggatac gatgtatata agcacactca gtacgaaatc ggcgaatgcc
     1441 ctgattaagg gattcggcga gaattattat aataaagcgt atctggcaac caagagggat
     1501 tatatgacaa tctcgttggg gcggctcagc gcctttccat gtttctccgt gatcaatgag
     1561 ttgatcggaa atcagaatgg cgtagttggc gggtatgtaa ctgtctttaa ggatgaggta
     1621 gaggcagctg taaaccgggt cgtctctatc ttgaaaggaa cgcccccgtc cgattttccg
     1681 caaatcgaag agagtaacaa ggcttatgtt tttgattacg gtgtgttaga acgatggagc
     1741 attgatagta gtaaattgcc ggaaggagct attatcgcga atatgccgtt tgtcgttcaa
     1801 tataaatatt atatatgggc tgccggcttt attctggtgg tgatgttgct tctgcttttt
     1861 agttaccaaa gaaagcgata tatacaggag gctttacata agaaggatgc gcaggagaag
     1921 ttaaaaaggg agaagacttt tctttctttt gcgttggata gcggcaacat tttcgctttt
     1981 cggtatagca aaggggtatt cgagtttgat aatagattct accattactt aggtatgccc
     2041 tgtgtgccga tgaaaatcga ggagtttcag gatgctatac atcctgaaga actggataat
     2101 ttccttcgag accggaatct gctggatagt ggctttcttt cccggaaagt gacgcaacgt
     2161 cgttgtaact ttaataagaa ggggtatgag tggtgggaat ttcgctatgc ccaaaataag
     2221 aatgagaaag attcggtttc cgatgacgaa gctgttgagg taagtggctt atgcttgaat
     2281 atccagcgga taaaagacac ggagaatagc cttatagccg cccgccggaa agcggaggaa
     2341 tccgatcgga tgaaattagt ctttctggcg aatatgagcc atgagatacg tacgcctctg
     2401 aatgcgatcg taggcttctc ccaattgctc aattcggata tgcctttgga accggaggaa
     2461 aaggcggagt ttatagatct gattaccaaa aacagtgacc tgttgcttaa gctgatcaac
     2521 gatatcttgg atctatcacg catagaatcc ggtagcatgt ctttctctta tgagaacctc
     2581 gatctgagta aactgatggg agatatcttc catacgcatc aattgatgat gccggaggga
     2641 gtggagttaa agataagggt tccccatgaa cctcttatca tccgttcgga tcatttccgg
     2701 ttgacgcagg tttgtaccaa tttcattaat aatgcggtga agtttaccgc taagggatat
     2761 atcgagatcg gatacgaact tagcgcagat ggaaaatcga tccttatttc cgtgaaagat
     2821 acgggtaagg gcattcctga tgataaaaag gaaaaggtat tcgagcgttt ccagaaactg
     2881 gatgagtttg ctcaaggtac aggcttgggg ttagcgatct gccagagtat cgttcatacg
     2941 tttcatggaa gcatatcgtt ggaatccgag gttggcgtag gtagtaagtt tacgatctcg
     3001 ctaccttata ccccgggatt ggagctggag gaaagaactt aattaccttc gatgaatcgt
     3061 ttattggctc tcgcttcttc ctgccattgg gggatgacgg tttctaaaaa cttttgtttg
     3121 gcctgttgct cggcttccat atcgaggccg atatattgct gggctttcgc ttttgtggag
     3181 atatccggca tcggaacatc ttgggtatag cctagctgcg ctaagacctt catgatctgg
     3241 atgcgggctt gggtagcctt atcgagtccg ctgcccaaga tacgtgtgac ttcttggggc
     3301 gcgtggaaag ccgccccgtg tgaggccacg gcgaagtccc aacgccattg tgcctgccgg
     3361 agcagtttta atacgttttt catttgagat tccgtagcgc ctttgtccca agcgaatttc
     3421 gcttctatat gggcttttgt caattcttcc tctacacgca tgcgtatggc gtagactttg
     3481 ttttgccgtt cataaacatc cttgcgtaag gtctcctcac tttcccggtg gcaggcttgg
     3541 caagtacggt ctatcatcgc caacgggctt ttgatatgat ggttgttgta ccggttctca
     3601 tcttccccga cagcaggcat atggcattct ccgcaggaaa cgcctctttg cccgtgaatg
     3661 cccatctgga ataactcgaa atccggatgt tgcgccttta tcaaatgtgc ccggcttaat
     3721 ttatgggtga aatcggtgaa gtttatgctg tcgtaatagg cttctatatt ttctaccgta
     3781 taaccttgat cccaaggtaa ggttagtata cgatcttctc cttggaaata atattcggcg
     3841 tggcattggg cgcatactag agatcgcatc tcttgctcgg ttgcgtcctc tatacgtaat
     3901 ccgttgcgct tataggcact tttcaagaat gagcgggtca cgcgcaatcc catgctttgc
     3961 ggttcatggc agtctgcgca tccgattgga tttacgatct cgttgcctag ctccgcccat
     4021 ttcttcttat ataaggtctt ggcatcggtg gtcgttaata agcggggtat gtccggactt
     4081 ttacatgtcc agcatgcggc aggctggggg ccactcgtcg gggtcatggg agagccggtc
     4141 cgcaggcttt tgtatagatc ttctatggaa tacatatgcc ctctgggact tagataatct
     4201 ttagagaaag cgtatcctgc ccataatacc accattacgg gatgttcggc caagatatca
     4261 gcttgttggt tcccattaaa caaactgcgg aaagtcgtgt ccgaggtttg tttccaactt
     4321 tggtactcat tggaataacg aaggtctata gagtcgctgt tttgttgatc tattggctga
     4381 tcatcggtat cgtcgatgaa tttgatgcta tcttgtccgg taacagtggt acgtaagatc
     4441 actaatacga taatgacgat tagacttatg gctatagaag ttttatagtg tgctttcaag
     4501 tgtttacctt ttatcttaaa taaaatattc tttgtattaa ctgcgaatat atgaataata
     4561 atgatacgac cggtagaaat tgaaaaaatc cttatttcat tgcttccgaa gacgctagat
     4621 gaaataagga ttctcaagtg actcgcatag gattcaaacc tataaccttc tgatccgtag
     4681 tcagatgctc tattcagttg agctagcgag ccaatctgta aatgaa
//
LOCUS       DBMDTB010000172         4723 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_4339_length_4723_cov_11.801601, whole genome shotgun sequence.
ACCESSION   DBMDTB010000172 DBMDTB010000000
VERSION     DBMDTB010000172.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 4723)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 4723)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4723
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_4339_length_4723_cov_11.801601"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..513
                     /locus_tag="ACZPB4_16405"
     CDS             <1..513
                     /locus_tag="ACZPB4_16405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HIR1099832.1"
                     /translation="VENMDFAYTTISLNKTYQMGFDQALQVIERNGGSVSGDEVTIKC
                     QQPVAVRYEKAFEGMYPIEKVAVNKNLPDVGELPFEGTGAVFKGFVNAKDDKYVARVE
                     MYLDGELVETANLPASYTTRRNDLFWKYQLPKGKHTATFKWLNPRNDVSVHFSEILIY
                     SDAPKEIVHQ"
     gene            526..1542
                     /locus_tag="ACZPB4_16410"
     CDS             526..1542
                     /locus_tag="ACZPB4_16410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016799 - hydrolase activity, hydrolyzing
                     N-glycosyl compounds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HIR1099833.1"
                     /translation="MKKSLFLMGLFALLISCKGNVSKNIPQTDKPQPVNLILDTDLGP
                     DYDDVGAMALMHALADSGQVNILATLSSNHDERVIPCIEVLNTYFNRPDIPVGAPKSE
                     PGASLTTWHKTKWTDELPANYPYHTAKTSDAPDALKVYRKILSEQPDTSVVICTIGFF
                     SNLRDLLQSGADEYSDLSGKELVAKKVKRLVSMAGLFPEGKEFNVYCDVPASKVVANE
                     WPTEIVFSGFEIGNVILTGKKLVQMNVENSPVKDAYALCFAEGDPEGRMSWDHTAVLV
                     AIKGYEPYFDVERGTFHVVDDEGTNNWVANPNGRDLRLIEKMPPTEVASLIENYMMHQ
                     PSIK"
     gene            1550..2551
                     /locus_tag="ACZPB4_16415"
     CDS             1550..2551
                     /locus_tag="ACZPB4_16415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HIR1099834.1"
                     /translation="MYIVQDYSLAVIFCVVTMLCWGSWGNTQKLASKTWRYEFFYWDY
                     VIGVLLFSLISGFTLGSIGTEGRSFLPDLAQANLASLGSAFLGGIIFNAANILLSAAI
                     AICGLSVAFPVGIGLALVLGVLVNYFGAAKGEPTYIFIGVALITIAIILNGLAYKKAL
                     VGTKKVSGKGILISVVAGVIMAFFYRFVAASMDMENFASPAPGKLTPYTAVFVFAIGV
                     FVSNFLFNTLAMKHPVEGKPVSISGYFKGDMSTHLVGVLGGVIWCIGQSFSMIASEKA
                     GAAISYGLGQGATLVSALWGILIWKEFKGAPAISNRLNVGMFILFVIGLGFLIYAGA"
     gene            2641..3390
                     /locus_tag="ACZPB4_16420"
     CDS             2641..3390
                     /locus_tag="ACZPB4_16420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099835.1"
                     /translation="MKEEGDVFKKFRDSFSRMEGHFHILEQRVPVELQMEYFKYSENV
                     RKENRPPRPLSEDECETLYNTLLTEETTDKTEKRYLLSQLATSKSVRAYRLLEEYTQH
                     PDPEVTDWAYMALMESRISLESDFSDEKQIYISTGLGGKGEKLRFYVLMTSKGKKPFQ
                     EYQRQTIEREFAYYLPKTDCEIERLTIGEQYVELVFLIPVRTDIKATLDRVINECNQY
                     GDFLSNVFTITNVKELTPEEISEIISKNGDD"
     gene            3377..3757
                     /locus_tag="ACZPB4_16425"
     CDS             3377..3757
                     /locus_tag="ACZPB4_16425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HIR1099836.1"
                     /translation="METIKQAIKYGVVGLSNTLITMIVIWVMMKLFGCREGLSNLTGY
                     VAGILNSFIWNKQWTFKGSSTGWTKGAVRFTIAFIICYALQYGLVLILNSRLTIDHYY
                     NHLIGMAFYTVINFLVNKFYTFKA"
     gene            3763..4695
                     /locus_tag="ACZPB4_16430"
     CDS             3763..4695
                     /locus_tag="ACZPB4_16430"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HIR1099837.1"
                     /translation="MKKLAVIVPCYNEEAVIEESYRRTKEVLVKLPNPTEIIYINDGS
                     QDKTRSLLDHIAATDPLVKVIHFSRNFGHQPAVTAGINNCDADLAIIIDADMQDPPEL
                     IPDLLEVQEREDANVVYCVRKSREGESLFKLFTSKAFYRVMNYMSEVHFPLDTGDFRL
                     VDRKVMNEFDRFKERGKYIRGLISWVGFHQVPFYYEREARIAGETKYPISKMLKFAST
                     AMLYFSKKPLRLATSLGFISVLVGIILAVWFTLGKIYGFSNAEVGWTSIMTSIIFFGG
                     VQLLTVGVLGQYVGILFDEIKARPEYIIDEKKNY"
BASE COUNT         1207 a          912 c         1262 g         1342 t
ORIGIN      
        1 gtggagaata tggattttgc ctatacgacc atctcattga ataagactta ccaaatgggc
       61 ttcgatcaag cgttgcaagt gatagagcgc aacggcggtt ccgtttcagg tgacgaggtg
      121 acgatcaaat gccagcaacc tgtagccgtt cgttacgaga aggctttcga gggtatgtat
      181 ccgatagaga aagtggcggt taataagaat ttgcccgatg taggagaact gccttttgag
      241 ggaacaggcg ccgtattcaa aggctttgtg aacgctaaag atgataaata cgtagcgaga
      301 gtagagatgt acctagatgg ggagctggtt gagacggcga accttccggc atcctatacg
      361 actcgtagga acgacctgtt ctggaagtat cagctgccca agggaaaaca tacggctacg
      421 tttaaatggc taaatccacg taatgatgtc tccgttcatt tcagcgagat actgatttac
      481 tcggatgctc cgaaagagat tgttcaccaa taaattataa agattatgaa gaaatcattg
      541 tttctgatgg gcttatttgc cttgttgatt tcctgtaagg gaaatgtgtc gaaaaatatt
      601 cctcaaaccg ataagcctca accggtaaat cttattctag atactgattt aggtccggac
      661 tatgatgatg tgggcgctat ggccttgatg catgccttgg cggatagcgg tcaggtaaat
      721 atccttgcga ctctttcctc caaccatgat gagcgggtga taccttgtat tgaggtgttg
      781 aatacttatt tcaaccgtcc ggacataccg gtaggggcac caaagagcga accgggggct
      841 tccttgacta cttggcataa aacgaagtgg acagacgagt tacccgctaa ctatccgtat
      901 catacggcga agacttccga cgctccggat gctctgaagg tgtaccgtaa gattctgagc
      961 gaacaaccgg ataccagcgt tgttatttgt acgattggtt tcttctctaa tttaagggac
     1021 ttgcttcaat cgggagctga tgaatatagc gatctctccg gaaaggaatt agtcgccaag
     1081 aaagtgaaac gtttggtttc tatggcgggc ctgtttccgg aaggaaaaga atttaatgtg
     1141 tattgcgatg tccctgcctc taaagtcgta gcgaatgaat ggcctacaga gattgtcttt
     1201 agcggttttg agatcgggaa cgtaatcttg accggaaaga aactggtgca aatgaacgtg
     1261 gagaacagtc ctgtaaaaga tgcgtatgcc ctttgtttcg cggagggaga cccggaaggg
     1321 cgcatgagct gggatcatac ggcggtattg gtcgctataa aaggttatga gccttatttc
     1381 gatgtagagc gaggtacctt tcatgtcgta gatgatgagg ggactaacaa ttgggtggca
     1441 aatcccaatg gccgtgatct tcgtttgatc gagaagatgc cgcctacgga ggtcgcttcc
     1501 ttgatagaga attatatgat gcatcaacca tctattaaat agtattttta tgtatatcgt
     1561 acaagattat tctttagctg tcatattctg tgtcgttacg atgctttgtt ggggatcgtg
     1621 ggggaatacg cagaaattag cctccaagac ttggagatat gagttcttct attgggacta
     1681 cgtgattggt gtcttgctct tttctctgat ttccggcttt accttgggca gcatcgggac
     1741 ggaaggacgc agtttcctgc cggatttggc gcaagcgaat ctcgctagtt tagggagtgc
     1801 ctttttgggc ggtattattt ttaatgctgc caatatcttg ttgtctgcgg cgatcgccat
     1861 ttgcggattg tcggtcgctt ttccggtagg gatcggattg gccttggtgc taggcgtatt
     1921 ggttaactat ttcggggcgg cgaaggggga accgacttat atctttattg gtgtagcctt
     1981 aatcacgatc gccatcatct tgaacggcct ggcttataag aaagccttgg tcggtaccaa
     2041 gaaagtatcg gggaagggga tccttatatc ggttgtggcc ggcgtgatca tggccttttt
     2101 ctatcgtttt gtcgccgctt ccatggatat ggagaatttc gcttctccgg cacccgggaa
     2161 gttgacgcct tataccgccg tatttgtttt tgccatagga gtatttgtta gtaatttctt
     2221 atttaacaca ttggcaatga aacatccggt ggaaggtaag cctgtctcca tatccggtta
     2281 ttttaaggga gatatgagta cgcatctcgt gggtgtattg gggggtgtta tctggtgtat
     2341 cggtcaatct ttcagtatga tagcgtcaga gaaagcggga gcggctatat cttacggatt
     2401 ggggcaagga gccacgctag tctccgcttt atggggcatc cttatctgga aagagttcaa
     2461 gggagcgcca gccatttcca atcgtctgaa tgtcgggatg tttattttat tcgtgatcgg
     2521 acttgggttc ttaatttatg cgggagctta aataacgtta tttttattta ttccggaaaa
     2581 aacattacct ttgttcttgt ttcttgttta tgggagttta ataacgaaaa aagacgatct
     2641 atgaaagaag aaggtgatgt attcaaaaag ttccgtgatt ccttcagcag gatggaggga
     2701 catttccata tactagaaca gcgtgtgccg gttgaacttc agatggagta tttcaaatac
     2761 tcggaaaacg tacggaagga aaaccggcct ccccgtccct tatcggagga tgagtgcgag
     2821 accctgtaca acactttgtt gacggaggaa accacggaca agaccgagaa gagatatttg
     2881 ttatctcaat tggctacctc gaaatccgtc cgtgcgtacc gcttgttgga ggaatacacc
     2941 cagcatccgg acccggaagt gacagattgg gcctacatgg ctttgatgga gtctcgtatc
     3001 tccttagagt ccgatttctc cgacgagaaa caaatttata tctcgaccgg cttgggagga
     3061 aaaggggaga agctgcgttt ctatgtcttg atgacgtcta aaggcaagaa acctttccaa
     3121 gaatatcagc ggcagacaat cgagcgggag ttcgcttatt atctgccgaa aacggactgc
     3181 gagatcgagc gtttgacgat cggtgagcag tatgtggagc tggtgttctt gatcccggta
     3241 cgtacggata taaaagccac gttggaccgg gtgatcaatg aatgtaacca atacggcgat
     3301 ttcctctcga atgttttcac gatcacgaat gtcaaggaat tgacacccga ggagatttcc
     3361 gagattataa gtaagaatgg agacgattaa gcaagctatt aagtatggtg tagtcgggtt
     3421 gagcaatacc ttgataacga tgattgttat ctgggtgatg atgaaactct tcggatgccg
     3481 ggaaggttta tctaacttaa cgggatatgt ggcaggcata ttaaacagtt tcatctggaa
     3541 caagcaatgg actttcaagg gaagttccac cggatggacg aaaggggcgg ttcggttcac
     3601 gatcgctttc attatttgtt atgccttaca gtacggattg gtactgatct tgaattcccg
     3661 acttacgatc gatcattact acaaccactt gattggaatg gctttctata cggtgattaa
     3721 ttttttagta aataagtttt atacctttaa agcttaaaag gcatgaagaa gttagcggtt
     3781 atagtcccgt gttataacga ggaagccgtg atcgaggaat cgtatcggcg tacgaaagag
     3841 gtcttggtaa agttgccgaa ccctacggag attatctata taaatgatgg cagtcaggat
     3901 aagacacgtt ctttgttgga ccatatagcc gctaccgatc ctcttgtgaa ggtgattcac
     3961 ttctcccgga atttcggtca tcaaccggcg gtaacggcgg gtatcaataa ctgtgacgct
     4021 gatttggcga ttatcatcga cgccgatatg caggatccgc cggaattgat tccggatctg
     4081 ctggaagtgc aggagagaga ggatgccaac gtggtttatt gcgtccgtaa gtcacgggaa
     4141 ggggagagtc ttttcaagct gttcacctcc aaggcttttt accgggtgat gaattatatg
     4201 agcgaggtcc atttcccgct ggatacagga gatttccgtt tagtggaccg gaaggtgatg
     4261 aatgagttcg accgttttaa ggaacgggga aaatatatcc gtggcttgat aagctgggtg
     4321 ggcttccacc aagtgccgtt ttattatgag cgtgaggcgc gtatcgccgg cgagacgaaa
     4381 tatccgatta gtaagatgct gaaattcgcg tcgacggcaa tgctttattt ctcgaagaag
     4441 ccgttgcgtt tggcgacgag tctcgggttt atatccgtat tggtcggtat aatcttggcg
     4501 gtttggttca cgttgggcaa gatctatggt tttagtaacg ccgaggttgg ctggacttct
     4561 atcatgactt ccattatctt ctttggaggt gtacagttat tgacggtcgg cgtgttaggg
     4621 caatatgtcg gtatcctctt tgacgagatc aaggcccgtc ccgaatacat tattgacgag
     4681 aagaaaaact attaaaaaac atcggaggcg aaataagccg ttt
//
LOCUS       DBMDTB010000173         4624 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_4430_length_4624_cov_11.614415, whole genome shotgun sequence.
ACCESSION   DBMDTB010000173 DBMDTB010000000
VERSION     DBMDTB010000173.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 4624)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 4624)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4624
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_4430_length_4624_cov_11.614415"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(148..831)
                     /locus_tag="ACZPB4_16435"
     CDS             complement(148..831)
                     /locus_tag="ACZPB4_16435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinB family protein"
                     /protein_id="HIR1099838.1"
                     /translation="MKYFGAGLSESHKELNRIIRKPELIEQTKELFLEIHGKLHLSVV
                     SGNERNEVDELVGDLREDEYAIIPTAKDETIAWVLWHISRIEDLTMNILVNGEKQIFN
                     EDWQTRMNSPIRDTGNALSDNQIIQLSKSLRIQELLEYRNEVGRKSREIIRTLSPDDI
                     RRKIPTQRISRILEEGGITNHEDSIWLLDFWAKKDIAGILLMPPTRHVMLHLNDCCKW
                     KLAIRGRHH"
     gene            complement(840..1160)
                     /locus_tag="ACZPB4_16440"
     CDS             complement(840..1160)
                     /locus_tag="ACZPB4_16440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbjQ family protein"
                     /protein_id="HIR1099839.1"
                     /translation="MLLTTTNTIEGKEITQYFGIVSGETIIGANVFKDFFAGIRDIVG
                     GRAGSYESVLREAKETALKEMSDHAARMGANAVIAVDLDYETVGGSGSMLMVTAAGTA
                     VRYQ"
     gene            complement(1255..3513)
                     /locus_tag="ACZPB4_16445"
     CDS             complement(1255..3513)
                     /locus_tag="ACZPB4_16445"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HIR1099840.1"
                     /translation="MKRTILFFQAALACLLVGCKQAPESPRLQDEVRYVDPFIGTGFH
                     GHTFPGATRPYAMVQLSPDTHILGWDASSGYHYDDDHIYGFSHTHLSGTGIGDLGDVA
                     LLPFSGGDSIKPVATFKKDTEKATPGYYAVRLDNFGINVELTSTDRVGFHKYTYDNPK
                     ERRVLLDLGHILQPNWGHKLIGNQYLLVNDSTVEGTVKTQGWAHFHSMSYRITFSEPI
                     ETVYQYIGGKLRKDSLFLRLNTAEDLKFHYKFAEKAQPLYVKVALSVVDPEGAEKNLE
                     AELPGWDFDKTREESTHIWNEALNLIQIEADPKVMVNFYTALYHTMIAPFAYQDVDGR
                     YLGMDKKVHTAEPGYVNYSVFSLWDTFRALHPLMTIINPDLATDWGKVLVQGYKEGGI
                     LPKWPLASSYTGCMVGYPAVSVLADLVAKDLAEGDMSTWAEAGARSSVYREDLAEKFK
                     GTRELDLITMHPYYKEKYGFVPADSVPESVSWGLEMAYEDWCISQIAKKAGNIELANE
                     YAKKAEYYKRYLDPETKMMRPVMGDGSFRTPFNPRYSSHMKSDYTEGNAFQWSFFAPH
                     DMDNFIAAIGGKKELETRLDTLFTTSSQIDGAEASGDITGLIGQYAHGNEPSHHMAYL
                     YNWTDSPWKGQGYLDYIMQNFYTNEPDGIIGNEDCGQMSAWYVMSALGFYQVSPGIPV
                     YTLGRPMVNKASMHVKGGIFEIVATNNSPANKYVKEVKLNGKVLETPFISHSDIINGG
                     KLEFIMTDQPVK"
     gene            3653..3910
                     /locus_tag="ACZPB4_16450"
     CDS             3653..3910
                     /locus_tag="ACZPB4_16450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HIR1099841.1"
                     /translation="MGTNEFTTKILPLKNNLFRVVFRITGDVEQSEQIVQEALLKVWE
                     DRDSWIVIENLPSYCMMVARNLALRETYSGNKERMERYAVR"
     gene            3929..4591
                     /locus_tag="ACZPB4_16455"
     CDS             3929..4591
                     /locus_tag="ACZPB4_16455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099842.1"
                     /translation="MDYQRINKLLDKYWECATSVEEERELRQFFSSAVVPPDLLPYKT
                     WFVSHEAEALPPLGKEFDARILEHISEDRKLITTFGTLFKSITHLIHKIMGTNMKKAF
                     TTLLCLLFCITISAQDKAADLSKLVGDWSFSAPDAPYGYQDGSFQIKQENGKLTAKVN
                     IQGSTLEINDIKAKGDTYTSSFYVDGTPVDLTMTQKGNELEGMADAGGMQIPVKFKKT
                     KK"
BASE COUNT         1191 a         1033 c         1046 g         1354 t
ORIGIN      
        1 agaagttaag cctcgtcacg ccgatggtac tgcgtaacag tggaagagta ggtagccgcc
       61 gtcttgagaa aggcgaaagc cggaagagag aggagtcagt cgaaagattg gctccttttt
      121 ttgttatata cactagccgt ttaattttca atgatgtctg cctcttattg ctagcttcca
      181 tttacaacag tcatttagat gtaacatgac atgtctggta ggaggcatta ataaaatacc
      241 agctatatct tttttagccc agaaatcaag caaccaaatc gaatcttcat gatttgtgat
      301 accaccttct tctaatatcc ggcttatcct ttgagttggg attttgcgac gtatatcatc
      361 gggagataag gttcggatga tttctctgct ttttcgtcct acttcattcc tgtattctaa
      421 gagttcttga atacgtagac ttttgcttag ctgaataatc tggttatcag ataaggcatt
      481 tcctgtgtct ctgatagggg aattcattcg ggtttgccag tcttcattga agatctgctt
      541 ttccccgtta actaatatat tcatggtcag atcctcaatt ctgctgatat gccataatac
      601 ccaagcgatg gtttcatctt tcgctgtagg tataatggca tattcatcct ctcttaaatc
      661 tccgactagc tcatcgacct cgtttctctc attaccagac accacagaga ggtgtaattt
      721 tccatgaatc tcaagaaaga gctccttggt ttgctctatt aattccggtt tacggataat
      781 gcggtttagt tctttatgtg attcgcttaa tccggctcca aagtatttca ttttggggat
      841 tattggtagc gtacggctgt cccggcggcg gtaaccatca gcatgcttcc gcttcctcct
      901 acggtctcat aatctagatc tacggcgatt acagcgtttg cgcccattcg tgccgcatga
      961 tcgctcattt ctttcaaggc cgtttctttc gcttcgcgta agacgctctc gtaagaacct
     1021 gcacgtcctc cgacaatatc ccggatgcct gcgaagaaat ctttgaatac attcgctccg
     1081 atgatcgttt caccggatac gattccgaag tactgggtaa tttcttttcc ttcgatcgtg
     1141 ttagttgttg tgagtaacat agcttttcaa tttaatcgtt tgagggcaaa tataagataa
     1201 agggcgaacc agtgtactga ttcgcccttt gtttttatgt ttctttatat gaatttattt
     1261 taccggttga tcggtcatga taaactcaag cttacctcca tttatgatat cggagtggct
     1321 gatgaaagga gtctctagga ctttaccgtt tagcttgact tctttaacgt atttattggc
     1381 gggactattg ttggtcgcca cgatctcgaa aataccgcct tttacgtgca tagaagcctt
     1441 atttaccatc ggacggccca atgtgtaaac cggaataccc ggacttacct gatagaaacc
     1501 tagggcgctc atgacatacc aagcagacat ctgtccgcaa tcctcattac cgatgatacc
     1561 atccggttca ttcgtgtaga aattctgcat gatataatct aaataccctt gccctttcca
     1621 tggagaatct gtccagttat aaagataggc catatggtgg ctcggctcgt ttccatgagc
     1681 gtattggccg atcaatccgg taatatctcc ggaggcttcc gccccgtcaa tctgggaaga
     1741 ggtggtgaac agggtgtcta aacgtgtttc cagctctttc ttgccaccga tagcggcgat
     1801 gaagttatcc atatcatgtg gtgcgaagaa actccattga aaggcattcc cttcggtata
     1861 gtcgcttttc atatgcgaag aatagcgagg gttgaatgga gtacggaaag aaccgtcgcc
     1921 cattaccgga cgcatcattt tcgtctcggg atctaaatag cgtttgtagt attcggcttt
     1981 cttggcatac tcattcgcca actctatatt acctgccttc ttggcgattt gggagataca
     2041 ccaatcctcg tatgccatct ccaatcccca cgatacggat tcgggaacag agtcggcggg
     2101 gacgaaacca tatttctcct tatagtaagg gtgcatcgtg atcagatcca actcacgggt
     2161 tcctttgaac ttctcggcaa gatcctcacg gtaaacggaa gaacgtgcgc cggcttccgc
     2221 ccacgtgctc atatcacctt ccgctaaatc tttcgctaca aggtcggcga ggaccgagac
     2281 ggccggatat cctaccatac aacctgtata actagaggct aaaggccatt tgggtaatat
     2341 tccaccttct ttataacctt gcacgagtac cttgccccaa tcagtcgcta agtccggatt
     2401 aatgattgtc attaacggat gaagcgcacg gaacgtatcc cacaaggaga atacggaata
     2461 atttacgtaa cccggttcgg cggtatgcac tttcttgtcc atacccaaat aacgcccgtc
     2521 cacgtcttga taagcgaagg gggcgatcat ggtatggtag agcgccgtat agaaattgac
     2581 catgactttc ggatctgcct cgatctggat caagtttaac gcctcgttcc aaatatgcgt
     2641 tgattcctca cgggtcttat cgaaatccca tccgggtaat tctgcctcga gattcttctc
     2701 ggcgccttcc ggatcgacta cggataaggc tacttttaca taaagcggtt gtgccttttc
     2761 agcgaatttg taatggaact tcaaatcttc tgccgtattt aggcgtaaga acaaggagtc
     2821 tttacgtaat ttccccccga tgtattggta taccgtctcg atcggttccg agaaagtaat
     2881 ccgataggac atagaatgga aatgcgccca accttgtgtc ttcacggttc cttccaccgt
     2941 ggagtcgttt acaagtaaat attggttacc gatcagctta tgtccccagt tcggttgaag
     3001 gatatgccct aagtcaagca ggacacgacg ttctttggga ttgtcgtatg tatatttgtg
     3061 gaaacctaca cgatccgtag aagtcaattc cacgttgatg ccaaagttat ccaagcgtac
     3121 ggcataatac cccggtgtcg ctttctcagt gtctttcttg aaggtagcta ctggtttgat
     3181 ggaatctcca ccggagaaag gtaataaagc tacgtcaccc agatcgccga tacccgtacc
     3241 agaaagatgc gtgtggctga acccgtagat atggtcatca tcataatggt aaccactact
     3301 tgcgtcccat cccaagatat gggtatccgg gcttagttgt accatcgcgt acggacgggt
     3361 agctccgggg aatgtgtgtc catggaaccc ggttccgatg aatgggtcta catacctcac
     3421 ctcatcttgt agtcgcggcg actccggcgc ttgcttgcat cctaccagca ggcaggcaag
     3481 agcggcctga aaaaataaga tcgttctttt cactgttatt attgatttag tttgtaataa
     3541 gcgaattatc aatcatctgt cacaaagata atggctttgg gggaatattg gaaatttcct
     3601 tttaaaatct gcaacctttt tcgggcttgg ctcgtcttat agataaaaaa gtatgggaac
     3661 aaacgaattt acgacaaaga tattgccgct gaagaataac cttttccggg ttgttttccg
     3721 gattactgga gacgtggagc agtctgagca gatcgttcag gaagccctgc ttaaggtttg
     3781 ggaagaccgg gatagctgga ttgtcattga gaatttacct tcctattgca tgatggtagc
     3841 gcgtaatctg gcattgaggg aaacgtattc cggaaataag gaaaggatgg agcggtatgc
     3901 ggtaaggtaa tctgtttatg gatcgtgtat ggactatcaa cgaataaata agttgctgga
     3961 taaatattgg gaatgcgcca catccgtgga ggaagagcgg gaattacgcc agtttttctc
     4021 ctcagcggtg gtacctcccg acttattacc ctataagact tggttcgtat ctcatgaggc
     4081 cgaggcatta ccccctttgg ggaaagaatt tgatgctcgt atattagaac atatctcgga
     4141 agatcgaaaa ttaatcacta catttggaac gttatttaaa tctattactc atttaattca
     4201 taagattatg ggaacgaaca tgaagaaagc ctttaccacc cttttatgcc ttttgttttg
     4261 tatcacgatc tcggcacagg ataaagccgc agatctcagt aagctcgtag gcgattggtc
     4321 cttctctgcc cccgacgctc cgtatggata tcaagatgga agttttcaga taaagcaaga
     4381 gaacggcaag ttgaccgcta aagtgaatat acaaggtagt accttggaga taaatgatat
     4441 caaggcgaaa ggagatacct ataccagctc tttttatgtg gatggaacgc ctgtagactt
     4501 aactatgacc cagaaaggaa atgagttaga gggaatggcc gacgccggag gtatgcagat
     4561 tcccgtgaaa ttcaagaaaa cgaagaagta accgctttgt ggtactgtga gtttctgtta
     4621 actt
//
LOCUS       DBMDTB010000174         4607 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_4455_length_4607_cov_10.323791, whole genome shotgun sequence.
ACCESSION   DBMDTB010000174 DBMDTB010000000
VERSION     DBMDTB010000174.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 4607)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 4607)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4607
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_4455_length_4607_cov_10.323791"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..1506)
                     /locus_tag="ACZPB4_16460"
     CDS             complement(<1..1506)
                     /locus_tag="ACZPB4_16460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK 4TM domain-containing
                     protein"
                     /protein_id="HIR1099843.1"
                     /translation="MAKKTTTTKQNHTEPSWFAALKTFFTNERTRFITGLIISILTIY
                     VGLALISFFFTGAADQSKIENVPLGDLLTNRGSVENWTGVRGAYLSDLLMNRWFGISS
                     FMILFFLGSVGAKLMNLNKVSLLRRFLFSASVLIWGSVFFAFIFIKGYEDTFIYLGGQ
                     HGYYISEMFITNIGIPGTILLLLGSFLIIAIFTSKKTIPFLQRMFSLGWVKNRLKREG
                     REDEVEVDQTEKEDIVIPRSKPVVEQPDEQPEMDDYEEFDTEAELLEAEGKENRKTEP
                     EYQEEEVAGDDLVVTIAKGDDDPICEKTDEINTPESEDGEDAGFTVEVAAGNDETYDA
                     SALGTYDPRLDLSRYVFPTLDLLKAYDSGSMEINRDELAENQRLIKQALEDFNIKIAS
                     IKATVGPTVTLYEIVPEAGVRISKIKNLEDDIALSLSALQIRIIAPMPGKGTIGIEVP
                     NKNPQTVSMQSVIASRRFVEGKYELPVAMGKTITNEVFMFDLCKTPHLLVAG"
     gene            complement(1663..3183)
                     /locus_tag="ACZPB4_16465"
     CDS             complement(1663..3183)
                     /locus_tag="ACZPB4_16465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011965991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HIR1099844.1"
                     /translation="MLRKIRIFAATFCFVLITLLFLDFTGTIHAWFGWLAKIQFWPAL
                     LALNVGVVVGLIILTLLLGRVYCSVICPLGVLQDIISWFASKRKKYRFSYSPALKWVR
                     YGTLVIFILACIAGIGSLVALISPYSAYGRIASNLFAPIYQEGNNLLAYFAERMDSYA
                     FYSVDVWVRSLATMGIAILSFVILAILAWRNGRTYCNTICPVGTVLGFLSKYALLKPR
                     IDTDKCNGCGLCARKCKASCIDSKNHAIDYSRCVTCMDCLDNCRQGAISYTRAHKADK
                     ATSVKESSTKDTTDVSRRRALSATALVAMSSVLHAQQKKLEDYVEMKKDGGFAPIKER
                     KEPNRLAPLVPPGALSIGNLAQHCTGCQLCVSVCENHVLRPSTDLMKLMQPEMAFDRG
                     YCRPECVKCSEVCPTGAIKPITKEDKSAIQIGHAVWVKDLCIVNTDGMSCGNCERHCP
                     TKSIQMVAKDPADPKSLKIPVINTETCIGCGACEYLCPSRPYSAIYVEGHEMHRSI"
     gene            complement(3205..4590)
                     /locus_tag="ACZPB4_16470"
     CDS             complement(3205..4590)
                     /locus_tag="ACZPB4_16470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HIR1099845.1"
                     /translation="MSSCGKNENPQEMNRRKFLKVFGGGAVASSAALYGCAPKNEPGA
                     AVALGEVPTDKMTYRQHPTNGDKVSILGYGCMRWPLKQGSDGKDQIDQEAVNRLVDYA
                     IEHGVNYFDTSPVYVQGMSEKATGIALARHPRNSYYLATKLSNFQNYTRENSLAMYRQ
                     SFRDLQTDYLDYYLLHSIGGGNGIELFNDRYINNGMLDFLVKEREAGRIRNLGWSFHG
                     DVKVFDYVLDMGVKWDFVQIQLNYLDWKHASGRNVNADYLYGELEKRGVPAIIMEPLL
                     GGRLSNVPDHIVARLKQQRPENSVASWAFRFAGSPDGVLTVLSGMTYMEHLQDNIRTY
                     SPLIPVTDEEKDFLEETAQLMMKYPTIPCNDCKYCMPCPYALDIPGILLHYNKCVNEG
                     NVPKSAQDENYAKARRAFLVGYDRSVPKLRQANHCTGCEQCNPHCPQGIDIPKEMQRI
                     DKFVEELKVNG"
BASE COUNT         1352 a         1194 c          868 g         1193 t
ORIGIN      
        1 accggctacc aatagatgcg gtgtcttaca aagatcgaac atgaacacct cgttcgtaat
       61 cgtcttaccc atcgccacag gcaactcata cttaccctca acgaatcggc gtgaagcgat
      121 aacagattgc atcgataccg tctgaggatt cttattcggc acctcgatac cgatcgttcc
      181 ctttccgggc atcggagcga taatacggat ctgcaaagcg gataaactca aggcgatatc
      241 atcctccaag ttcttgatct tagaaatacg gacacccgcc tcgggtacaa tctcataaag
      301 cgtaaccgta ggtccgactg ttgccttgat cgaggcgatc ttgatattga aatcttccaa
      361 ggcttgcttg atcaagcgtt ggttttctgc caattcgtcc cgattgatct ccatgctccc
      421 actatcatac gctttcagta agtccaaggt aggaaataca taacgggaaa gatccaaacg
      481 gggatcatac gtacccaagg ccgaagcatc gtaggtttca tcattaccgg cggcaacctc
      541 caccgtgaat ccagcatcct ccccatcctc tgattccggg gtatttatct catctgtctt
      601 ttcgcatata ggatcgtcgt cacctttagc gatcgtaact actaaatcat caccagcgac
      661 ctcttcctcc tgatattccg gttctgtttt acggttttct ttcccttcgg cctccaacaa
      721 ttcagcctcc gtatcaaact cttcgtaatc atccatttcc ggttgttcat ccggttgctc
      781 tacgacaggc ttagagcgag gaattacaat atcctctttt tccgtctgat ccacttcaac
      841 ctcatcttct cggccttcac gtttcaaacg atttttcacc caacctaaag agaacatacg
      901 ctgcaagaac ggaatagtct tcttactggt aaaaatagcg atgattaaga atgagcctaa
      961 taaaagcaag atcgttccgg gaattccgat attggtaata aacatctccg agatgtaata
     1021 tccgtgttga ccgcctagat aaataaacgt atcctcatat cccttgataa atatgaaagc
     1081 aaaaaacaca gatccccaga tcaacaccga agcactgaac aagaaacgtc tcaacaagga
     1141 tactttattt aaattcatga gtttcgcccc aaccgatccc aagaaaaaga ggatcataaa
     1201 agaagagatg ccaaaccaac ggttcatcaa tagatcagac aaatacgccc cgcgtacgcc
     1261 cgtccaattt tctaccgatc ctcgattggt caacaaatcc cctaaaggaa cattctctat
     1321 tttactttga tcggcggctc ctgtaaagaa aaacgaaatc aaggcaagcc ctacgtaaat
     1381 ggttagtata gagataatca aacctgtaat gaaacgggtc cgttcatttg taaaaaaagt
     1441 cttcaaggct gcgaaccagc tcggctctgt atgattttgc tttgttgttg ttgtcttctt
     1501 tgccataaat agtttctcaa taattctttt ataacacgca aatgtacata gaaaaatcga
     1561 gtctgacgaa cctttgaaaa aaagacgtac gtgttttctg aaaaacatgt acatgttttc
     1621 gcggaaacac gtacatgttt ttggggatag attttaacgg cattaaatag atctgtgcat
     1681 ctcatgtcct tctacataga tcgcactata aggacgagat ggacaaaggt actcgcaagc
     1741 accacaacca atacaagttt ccgtattgat caccgggatc tttaacgact tcggatctgc
     1801 aggatctttc gccaccatct ggatcgattt tgtcgggcaa tggcgttcac aattaccaca
     1861 actcataccg tccgtattga caatacaaag atcttttacc catacggcat gaccgatctg
     1921 tatagcagat ttgtcttctt tcgtaatcgg tttgatcgct cccgtcgggc aaacctccga
     1981 acatttcaca cattccggac ggcaataccc tctatcgaaa gccatctccg gctgcatcag
     2041 tttcatcaga tccgtagacg gacgcaagac atgattctcg cagacagata cacaaagctg
     2101 gcaccccgtg caatgttggg ccagattccc aatactcaag gctccgggag gaaccaatgg
     2161 tgccaaacga ttcggctctt tacgttcttt aatcggcgca aagcctccgt ctttcttcat
     2221 ctccacataa tcctccagct ttttctgctg agcatgcaaa acagaagaca tggctaccaa
     2281 tgccgtagct gacaaggctc gacggcggga aacatccgta gtgtccttcg ttgaggattc
     2341 ttttaccgaa gtagctttat cagccttgtg tgccctcgta tacgaaatcg cgccttgacg
     2401 gcaattatcc aaacagtcca tacaagtcac gcaacggcta taatcgatcg catgattctt
     2461 agagtcgatg caagaagcct tgcatttacg tgcgcataat ccgcaaccat tacatttatc
     2521 ggtatcaata cgaggtttaa gtaaagcata cttcgacaaa aaaccgagaa ccgtacctac
     2581 cggacagatc gtattacaat atgtacgtcc atttctccaa gctaaaatcg ccaatatgac
     2641 aaagctcaga atagcgattc ccatcgtagc caggctacgc acccatacgt ccaccgaata
     2701 gaatgcgtaa ctatccatac gttctgcgaa ataggccaat agattgttgc cctcttgata
     2761 gattggcgca aataaattag aagcgatacg cccataagcg ctataaggcg aaatcaacgc
     2821 taccaaggaa ccgataccag cgatacaagc caatataaaa ataaccaagg taccataacg
     2881 tacccacttc aatgcgggag aataggaaaa gcggtatttc ttccgtttac tagcaaacca
     2941 cgaaatgata tcttgcaata cccctaaagg gcagataacg gaacaatata cacgccccaa
     3001 taaaagagtc aagattatca accctaccac aacaccgaca ttcaaagcca acaacgcagg
     3061 ccaaaactgt atctttgcca accatccgaa ccaagcgtga atcgtacccg tgaaatcaag
     3121 aaataacagg gttatcagca caaagcaaaa ggtggcggcg aatattctta tttttcgtaa
     3181 cataattttc cgtttgttta aaggttaacc attcactttc aactcttcca cgaatttatc
     3241 gatacgctgc atctctttgg ggatatcgat accctgcgga caatgaggat tacattgctc
     3301 acaccctgta caatggttcg cttgacgcaa ctttgggaca ctccggtcat aaccgactaa
     3361 gaaggcacga cgagctttcg cgtaattttc gtcttgtgcg cttttcggaa cattcccttc
     3421 gttcacacat ttattataat gtaagagaat acccggaata tccaacgcat atggacaagg
     3481 catacaatat ttgcaatcat tgcaaggtat tgtcggatat ttcatcataa gctgggccgt
     3541 ctcttccaaa aagtctttct cctcgtccgt taccgggata agcggggaat aggtacggat
     3601 attatcttgc aaatgctcca tataagtcat gccgcttagc accgtcaaga ccccatccgg
     3661 agagccggcg aaacgaaaag cccatgaagc cacgctattc tcaggccgtt gctgtttcaa
     3721 acgagcaacg atatgatccg gaacattcga taagcgacct cctaatagcg gttccatgat
     3781 aattgccgga acacctcgct tctctaattc gccatacaga taatcagcgt ttacgttacg
     3841 ccccgaggca tgtttccagt ccagataatt cagctgtatc tgaacgaaat cccatttcac
     3901 gcccatatcc aacacataat caaacacttt tacatcccca tgaaaagacc aacctaggtt
     3961 acggatacgt cccgcttccc gttctttcac caagaaatca agcattccat tatttatata
     4021 gcggtcattg aaaagctcga taccattccc cccaccgata gagtgaagca aataataatc
     4081 cagataatcg gtttgcaaat cacggaacga ctgccgatac atcgccaacg agttttctct
     4141 cgtatagttc tggaagtttg acagtttagt ggccaaataa taggagttcc taggatggcg
     4201 tgccaatgcg ataccggtcg ctttctcgga cataccttgt acataaacag gagaagtatc
     4261 aaagtaattc accccatgct ctatcgcata atccactaaa cgattcacgg cttcttgatc
     4321 aatctggtct ttaccgtccg atccttgttt caagggccaa cgcatacaac catatcctaa
     4381 aatagaaacc ttatcgccat tcgtaggatg ttggcgatag gtcattttat cggtaggaac
     4441 ctcacctaac gccacagccg cccccggctc attcttggga gcgcaaccgt aaagcgccgc
     4501 cgaagaggcg acagccccac ccccaaatac cttcaagaat ttacggcgat tcatctcttg
     4561 agggttctca ttctttccac atgaactcat aactcgatcg gtttttt
//
LOCUS       DBMDTB010000175         4551 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_4519_length_4551_cov_9.593258, whole genome shotgun sequence.
ACCESSION   DBMDTB010000175 DBMDTB010000000
VERSION     DBMDTB010000175.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 4551)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 4551)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4551
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_4519_length_4551_cov_9.593258"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..526
                     /locus_tag="ACZPB4_16475"
     CDS             <1..526
                     /locus_tag="ACZPB4_16475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="6-bladed beta-propeller"
                     /protein_id="HIR1099846.1"
                     /translation="SSFHKLQSHTIRPVDLERSACPIGCLAPEVAVEPGSGTVYAYAP
                     SYQPGNLLRDTLYIKQKRQSQALENLAGKNTLPLLPIRMGSRFWVSTYYNAEDESKNY
                     TFCYDTEKERCWQVKEGLKDNFYQTGNVRRMDPIDPYCHSYCFSKSGEDLRNTFPAQA
                     QGESLVLFIVKLKG"
     gene            612..3854
                     /locus_tag="ACZPB4_16480"
     CDS             612..3854
                     /locus_tag="ACZPB4_16480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016274954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S41 family peptidase"
                     /protein_id="HIR1099847.1"
                     /translation="MKKLLTCIALGFATTSYAVTPLWMRDVQISPDGTEIAFCYKGDI
                     YKVPAKGGTATQLTTQASYECTPIWSPDGKQIAFASDRNGNFDLFVMPSNGGTAQCLT
                     THSASEIPSAFTPDGKYVLFSASIQDPAQSALFPTSAMTELYKVPIGGGRTEQVLGTP
                     AEMVCFDKSGKTFLYQDRKGFEDEWRKHHTSSVTRDIWMYDTQTGKHTNLTDHAGEDR
                     NAVFTPDGQTVYFLSERNGGSFNVYSFPLNTPQSITAVTKFKTHPVRFLSTSSDNTLC
                     YTYDGEIYTQRPGVNPQKVRIDLIRDDQEQISDLNSSKGATSATVSPDGKQIALTLRG
                     EVFVTSADYNTTKQITNTPAAETGVCFSPDNRTLAYASERGGNWQLYLAKIARKEEAN
                     FPNATIIEEEVLLPSKTVERNYPQFSPDAKELAFIEDRMRLMVVNLETKKVRQVTDGS
                     TWYSTAGGFDYSWSPDGKWFTLRFIGNKHDPYSDIGLVSAQGGEITNLTNSGYTSTSP
                     QWVLDGNAILFTTERYGMRAHASWGSLNDAMLVFMNQDAYDKFRLSKEDYELQKELEK
                     EQKEVTGDKTDDKKKEDKADEKKDEKPKDIVVELKGIQDRILRLTPNSSEMGSAVISK
                     NGETLYYFSAFEDKYDLWKMDLRKKETKLLHKMNTGWANMEMDKEGKNLFLLGSNSMQ
                     KMDMGSEKLTPIHYQANLKMDLAAEREYMFDHVYKQEQKRFYNVNMHGVNWEAMTAAY
                     RKFLPHINNNYDFAELLSEYLGELNVSHTGGRFRPQTSGNVTANLGLLFDWNHSGKGL
                     LIAEVVEKGPFDHARSKVKAGTVMEKIDGQEITPDMDYSKLLNNKAKKKTLVSLYDPQ
                     TKERWEEVVLPISNGELNNLLYTRWVKQRAADVDKWSNGRLGYVHIQSMGDPSFRSVY
                     SDILGKYNDREGIVIDTRFNGGGRLHEDIEILFSGEKYLTQVTRGREACDMPSRRWNK
                     PSIMLQCEANYSNAHGTPWVYKHQHIGRLVGMPVPGTMTTVSWETLQDPTLVFGTPIT
                     GYRLSDGSYLENTQLEPDVKVANSPETVVKGEDTQLRTAVNELLKEIDKK"
     gene            complement(3856..>4551)
                     /locus_tag="ACZPB4_16485"
     CDS             complement(3856..>4551)
                     /locus_tag="ACZPB4_16485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099848.1"
                     /translation="CLFWGLVCFVIPVLYTPGFEYVISQYIDWFERLKVKNMLNMFAD
                     PQNISLLGVVRKISGNAEYSDMWLIIPGLILFCIPYLRISQYKYPAFRFMLLANVLLF
                     VVLFSTGSEASGYIIAMIGVAIWYICSVSPHKKYTYWLWITTLVIVGLSTTELVPSIV
                     RNGLIRPYVIKAWPCIVVWLTICYEMCFLDFSHSPYKAYHDLGRVNIACFLIEGYIIK
                     RDYSRQAMRVVSF"
BASE COUNT         1381 a         1096 c         1023 g         1051 t
ORIGIN      
        1 ttcctctttc cataaattac aatctcatac gatccgtccg gtcgatctgg aacgttccgc
       61 atgcccgatc ggttgtctcg ccccggaagt agccgtggag cccggaagcg gaacggttta
      121 tgcctacgcc ccctcctatc aacccgggaa cttattacgg gacactttat atattaagca
      181 aaagcggcaa agccaagcct tggagaacct tgccggaaag aatacactac ctttgctacc
      241 gatccgcatg ggtagccgtt tctgggtatc tacttactat aacgcagagg atgagtccaa
      301 aaattacacc ttctgttatg atacggagaa agaacgatgc tggcaggtaa aagaaggatt
      361 aaaagataat ttttatcaaa ccggtaatgt gcgacgaatg gaccctatcg atccctattg
      421 ccattcctat tgtttcagca aatccggaga ggatctgcga aatactttcc ccgcacaggc
      481 ccaaggggaa agcctcgtgt tatttatcgt gaaattgaaa gggtaaatcc agttaatatt
      541 tcaatagaga gcagactgat gggtacaaaa taatatgtat cttcgtacca ttctaaaaaa
      601 gcattaagta catgaaaaaa cttttaacct gcattgcctt gggctttgcg actaccagct
      661 acgctgtaac ccctttgtgg atgcgtgatg tacaaatttc tcctgatgga acagagatag
      721 cgttttgtta caaaggagat atctataaag taccggccaa aggaggaaca gcgacacaac
      781 ttaccaccca agcatcgtat gaatgcacgc caatctggtc tccggacgga aaacaaatcg
      841 ctttcgccag cgatcgtaac ggcaatttcg atttattcgt aatgccctcc aacggtggaa
      901 cggcacagtg cctcaccact cattccgcct ccgagattcc atcggccttt actcccgacg
      961 gcaaatacgt actcttctcc gcatccatac aagatcccgc ccagagcgcc ttattcccga
     1021 cctcggccat gacggaactc tataaagtgc cgatcggtgg cggacgtacg gagcaagtat
     1081 tgggaacacc cgccgagatg gtttgcttcg ataaatccgg aaagacattc ttataccaag
     1141 accgtaaggg cttcgaggat gaatggcgta aacatcatac ctcgtccgtc acccgggata
     1201 tatggatgta cgatacgcaa actggaaaac ataccaattt gactgaccat gcgggagaag
     1261 accgcaacgc cgtatttacc ccggatggac agacggttta ctttctgagc gaacgcaacg
     1321 gagggtcttt caatgtatat tcattccctc tcaacacccc acaatctata acggcagtta
     1381 ctaagttcaa gacgcatccc gtacgtttcc tctctacaag tagcgacaat acattatgct
     1441 acacatacga tggcgagatc tatacacaac gtccgggagt caatccgcag aaagtgcgga
     1501 ttgatttgat ccgtgacgat caagagcaaa tcagcgatct gaattccagc aaaggagcta
     1561 cctcagccac cgtatccccc gatggcaagc agatcgcctt aaccctaaga ggcgaggtat
     1621 tcgtcacctc ggccgattac aacacgacca aacaaatcac caataccccg gccgccgaaa
     1681 caggcgtatg cttctcgccg gataaccgta ccttggctta tgccagcgag cgtggtggta
     1741 attggcaact ttacttggct aagatcgccc gtaaggaaga agctaatttc ccgaacgcga
     1801 cgattatcga agaggaagtt ctcctgcctt ctaagaccgt agagcgtaat tatcctcaat
     1861 tctcgccgga tgctaaggaa ctcgctttca tagaagatcg tatgcggctg atggtagtca
     1921 accttgagac gaagaaagta cgccaagtca cggatggctc cacatggtat agtacagccg
     1981 gcggtttcga ttactcatgg tcgccggacg gtaaatggtt cacgctccgg tttatcggaa
     2041 acaagcacga tccttattcg gatatcggct tggttagcgc gcaaggcggg gagattacca
     2101 acctgaccaa tagcggttac accagcacct ccccacaatg ggtactggat ggaaacgcca
     2161 tcttattcac caccgagcgt tatggaatgc gtgcgcatgc ttcatggggc tccttgaatg
     2221 atgccatgct ggtattcatg aatcaagacg cttatgataa attccgcttg agcaaagagg
     2281 attatgagtt gcaaaaggaa ctggaaaagg agcagaaaga ggtaaccggg gacaaaaccg
     2341 acgacaagaa aaaagaagat aaagccgatg aaaagaaaga cgaaaagccc aaggatatcg
     2401 tagtggaact gaaaggaatc caagatcgta tcctacgtct tactcctaat tcctccgaaa
     2461 tgggtagcgc cgtcatctcg aagaatggcg agaccttata ttatttctcg gctttcgaag
     2521 acaaatacga cctgtggaaa atggacttgc gcaagaaaga gaccaagcta ctccacaaga
     2581 tgaataccgg atgggcgaac atggaaatgg ataaggaagg taagaacctg ttcttgttgg
     2641 gtagtaattc catgcaaaaa atggatatgg gatcggagaa actaacaccg attcattacc
     2701 aagcgaactt aaaaatggac ttggccgccg agcgtgagta tatgttcgac catgtctata
     2761 aacaagagca aaaacggttc tacaacgtga atatgcatgg cgtaaattgg gaagctatga
     2821 ccgccgccta ccgtaagttc ttgccacata ttaataacaa ctatgacttc gcagagttgc
     2881 taagcgaata tctgggagaa ctcaacgtat ctcataccgg aggacgcttc cgtccgcaaa
     2941 caagcggcaa tgttaccgcc aacctaggcc tacttttcga ttggaaccat agcggcaaag
     3001 gtttattaat cgctgaggta gtggaaaaag gcccgttcga tcacgcacgt tccaaggtaa
     3061 aagccggtac cgtcatggag aaaatagacg ggcaagaaat aaccccggat atggattact
     3121 ccaagctatt aaacaataag gccaaaaaga agaccttggt ttccctctac gatccacaaa
     3181 ccaaggaacg ctgggaagag gtagtcttgc ctatcagtaa cggtgagtta aataacttgc
     3241 tttatacccg ctgggtgaag caacgtgccg ccgacgtgga taaatggtcg aacggacgat
     3301 tgggatacgt ccatatccaa tccatgggag accctagttt ccgctctgtc tactccgata
     3361 tcctaggtaa atataacgac cgggagggca tcgtcattga tacccgcttt aatggtggtg
     3421 gacgtttgca tgaggatatc gagatcttgt tcagcggaga gaaatacctc acccaagtga
     3481 cacgtggccg ggaggcttgc gatatgccta gccgccgctg gaataaacct tccatcatgc
     3541 tccaatgcga ggctaattat agtaacgcac atggaacccc gtgggtttat aagcatcaac
     3601 acatcggacg tttagttggt atgcccgtac cgggaacaat gactaccgtc tcttgggaaa
     3661 ccctgcaaga tccgacgctg gtattcggca cacctattac cggttatcgc ctgtcggacg
     3721 gtagttactt agagaacaca cagctggaac cggatgttaa agtcgctaat tctccggaaa
     3781 ctgttgtcaa aggggaagat acgcaattga gaacagcggt aaatgaattg ctgaaagaga
     3841 tcgataaaaa gtagtttaaa acgagactac tctcatcgcc tgtcgggagt agtctcgttt
     3901 tattatgtaa ccttctatta aaaaacaggc gatattcact ctgcctaagt cgtgatatgc
     3961 tttataggga gaatgactaa aatccaagaa acacatctca tagcaaatgg tcagccacac
     4021 tacaatgcaa ggccaagctt ttatcacata cggacggatc agtccattcc ggacaatcga
     4081 tggaaccagc tctgtagtgg ataagccaac aatcaccaag gtagttatcc aaagccaata
     4141 agtatatttc ttatggggcg atacactgca tatataccag atagcgactc ctatcatcgc
     4201 tatgatatac ccactcgcct cgcttcccgt actgaataat acgacaaaca ataaaacatt
     4261 agctaatagc ataaagcgaa aagccggata tttatattgc gagatcctta aatatggaat
     4321 gcaaaataaa atcaagcccg gtatgataag ccacatatcg ctatactccg cattcccgga
     4381 tatctttcga accactccta ataatgatat attttgcgga tcagcgaaca tattcaacat
     4441 atttttcact ttcaatcgct caaaccaatc tatatactga gagatcacat actcaaaccc
     4501 cggtgtataa agcaccggga tcacaaagca aaccaatccc cagaaaagac a
//
LOCUS       DBMDTB010000176         4411 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_4675_length_4411_cov_12.819954, whole genome shotgun sequence.
ACCESSION   DBMDTB010000176 DBMDTB010000000
VERSION     DBMDTB010000176.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 4411)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 4411)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4411
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_4675_length_4411_cov_12.819954"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..872)
                     /locus_tag="ACZPB4_16490"
     CDS             complement(<1..872)
                     /locus_tag="ACZPB4_16490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunoglobulin-like domain-containing protein"
                     /protein_id="HIR1099849.1"
                     /translation="MKAYFIGLVIMGGCLLYGCHTKQKKGENSSDYSADSQSIARQDS
                     LPLPTDTHAASSVSTEGWTAKQIRDSIELFFGKEYDTLPPHLRKIRGNLTSLWNTDDS
                     VFLQLIIVEAPYVKAFKTYVFDSPLIRIGGGPYDRSPEESLCEDTTHFSMRVSPNVYP
                     TNIERIEIAITNHTDLEGMGGESYFIEHFDGKAWKGVPQPNFFVDIGYPIFPNETRDD
                     FSATLMPELKENPPGLYRVHKTVITGQGAGIVHYPLAATFYLSDNPEDYEEYTRFASR
                     LHEPRPMAEFKGGR"
     gene            963..2480
                     /gene="dnaB"
                     /locus_tag="ACZPB4_16495"
     CDS             963..2480
                     /gene="dnaB"
                     /locus_tag="ACZPB4_16495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008149502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HIR1099850.1"
                     /translation="MAEGTRNTGRGRKKPVEMLPDMGRLQPQARELEEAVLGALMLEK
                     DAYSIVSEILKPECFYEKAHEKIYAAIVDLALSQRPVDMLTVTEQLKKRGELEDVGGP
                     FYISQLTSKVASSAHIEYHARIIAQKYLARELISFTAMIQGKAFDETLDVEDLMQEAE
                     GKLFEISQRNVKKDVTQINPVIKDAMEMLQKAALQKEGLSGLRTGFEGLDKMTSGWQN
                     SDLIIIAARPAMGKTAFVLSMAKNMAVNFNTPVALFSLEMSNVQLVNRLIVNVCEIPG
                     EKIKSGRLESYEWEQLDFKIKELYDAPIFVDDTPSLSVFELRTKARRLVREHGIKCII
                     IDYLQLMNASGMNFGSREQEVSTISRSLKGLAKELNIPIIALSQLNRGVEARQGVEGK
                     RPQLADLRESGAIEQDADMVCFIHRPEYYKITEDERGNSLIGLAEIIIAKHRNGAVGD
                     VRLRFKSEFAKFMNVEEDIAVREFSSTMNGGDPMPPIPSAGADFLSQGSSNEVPF"
     gene            2610..>4411
                     /gene="pulA"
                     /locus_tag="ACZPB4_16500"
     CDS             2610..>4411
                     /gene="pulA"
                     /locus_tag="ACZPB4_16500"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051060 - pullulanase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HIR1099851.1"
                     /translation="MTRHLVPVSIYLSLLLSCNSPKEYKSFDEYPSYEGDDLELFYSP
                     TKSVFTLWAPTAEEVRLNLYASGEGGEPIRQLPMKSSDKGTWRISVSEDLKGSFYTFQ
                     IRIGDKWLDETPGIWAKAVGVNGNRAAVIDWAATDPEGWEADKSPELKSFSDIIIYEM
                     HHRDFSIAANSGVTHKGKFLALAENGTKGPGGVATGVDHLKELGVTHVHILPSYDYGS
                     VDETRLQDNVYNWGYDPKNYNAPEGSYSTDPYNPEARIREFKEMVRGLHRNGIRVIMD
                     VVYNHTFVGDGSNFSLTVPGYFYRHKLDGSYSDASGCGNETASERAMVRRYIVESVKY
                     WAEEYHVDGFRFDLMGIHDVETMNEVKAELTKLDPSIFVYGEGWTASDSPLPEDQRAI
                     KVNAPKLNDVAVFSDDLRDALKGSVFETTQAGFASGKPEGNEESIKFGIVGAIRHPQI
                     DYNQILYCKAPYANKPTQVINYVSCHDDLCLMDKLKLSAPKDATPDELIRFGKLAQTI
                     IFTSQGVPFMRAGEELLHDKKGVHNSYQSPDSINEIDWSLKAKNKDVFNYYKDLIALR
                     KSHPAFRIATAEGVREALQFQEVNQPGVVAYTLG"
BASE COUNT         1055 a         1025 c         1263 g         1068 t
ORIGIN      
        1 tctcttcctc ccttgaactc ggccatgggg cgaggctcgt ggagccggct ggcgaagcgt
       61 gtgtattcct cataatcttc cgggttatcg gataggtaga acgtggcggc caaaggataa
      121 tggacgatgc cggcgccctg tccggtgatg acggtcttat gcacccggta caatcccggt
      181 ggattttcct tgagctcagg catcaaggtg gccgagaaat cgtctcttgt ctcgtttgga
      241 aagatcggat agccgatatc tacaaaaaag ttgggttgcg ggaccccttt ccatgccttc
      301 ccgtcgaaat gctcgatgaa ataactttcg cctcccatcc cttctaggtc ggtatggttg
      361 gtgatggcga tctcgatccg ttcgatgttg gttgggtaga cattcgggct tactcgcatg
      421 gagaagtggg tggtgtcctc gcaaagagat tcctcgggcg accggtcgta agggcctccg
      481 ccgatccgga tgaggggcga gtcgaatacg tacgtcttaa atgcttttac atacggagct
      541 tccactatga taagctgtag gaagacggag tcgtccgtgt tccagaggga ggtcaggttg
      601 ccgcggatct tccgtagatg cgggggaagg gtatcgtatt ccttgccgaa gaacaattct
      661 atgctgtccc gtatctgctt ggcggtccat ccttccgtgg aaactgaaga tgcggcatgg
      721 gtatcagtcg gtaacggtag ggaatcttgc cgtgctatgg attgggagtc ggctgagtag
      781 tcgctactgt tttccccttt cttttgtttg gtatggcagc cgtataatag gcaacctccc
      841 atgataacta atccgataaa atacgctttc atgattcgac aggttttaat tcctaaatat
      901 aaagaatctt tttcagaaat gggtaaaaga tattaccttt gactccccaa atagaaagaa
      961 tgatggcaga aggaacaaga aatacaggaa gaggaaggaa aaagcctgtg gagatgctcc
     1021 ccgatatggg gcgtcttcag ccacaggccc gtgagttaga ggaggctgtg ttgggtgcgt
     1081 tgatgctgga gaaagatgcg tactcgatcg tcagcgagat cctgaagccg gagtgtttct
     1141 atgagaaagc gcatgagaag atttatgccg ctatcgtaga cttggcgttg agccagcgtc
     1201 ccgtggatat gcttaccgta acggagcaat tgaagaaacg gggagaattg gaggatgtag
     1261 gcggaccgtt ttatatctct caacttacca gcaaggtggc cagtagcgcc catatcgagt
     1321 atcacgcccg gatcattgcc cagaaatatc tggcgaggga gttgatctct ttcacggcga
     1381 tgatccaagg aaaggcattt gatgagacgc tcgatgtaga ggacctgatg caagaggcgg
     1441 agggcaagtt gttcgagatc tcgcaacgta acgtaaagaa ggatgtcacc cagatcaacc
     1501 ccgtcatcaa ggacgctatg gagatgttgc aaaaggcggc cctccagaag gaaggtctga
     1561 gcggattgcg tacgggcttc gaggggttgg ataagatgac ttccggttgg cagaattcag
     1621 accttatcat tatcgccgcc cgtccggcca tgggtaagac ggccttcgtt ctttccatgg
     1681 cgaagaatat ggcggtgaat ttcaatacgc ctgtcgccct gttctcgctc gagatgagta
     1741 acgtgcagtt ggtaaaccgt ctgatcgtga atgtctgcga gataccgggc gagaagatca
     1801 agagcggacg cttggagagt tacgagtggg aacagctgga ttttaagatc aaggagcttt
     1861 acgacgcccc gatcttcgtg gacgataccc cgagcttgtc cgtcttcgag ctgcggacga
     1921 aagcccgtcg tctggtgcgt gagcatggca ttaaatgtat cattatcgac taccttcagt
     1981 tgatgaacgc cagcggtatg aacttcggta gccgtgagca ggaggtgagt acgatctccc
     2041 gctcgttgaa gggattggcc aaggaattga atatcccgat catcgccttg tcgcagttga
     2101 accgtggtgt ggaagcccgt caaggcgtgg aaggtaagcg tccgcagcta gccgacttgc
     2161 gtgagtccgg agctatcgag caggatgccg atatggtatg tttcatccac cgtcccgaat
     2221 attataagat tacggaagat gagcggggaa attctctgat cggtcttgcc gagatcatta
     2281 tcgccaagca tcgtaacggt gccgtggggg atgtccggct gcgctttaag agcgagttcg
     2341 ccaagtttat gaacgtagag gaagatatag cggtaaggga attctcctcg accatgaacg
     2401 gtggagaccc gatgcccccg atcccatcgg cgggagctga cttcttgagt caaggtagca
     2461 gtaacgaggt tccgttctaa tatagcatga atgagcgaaa gaggcgaaaa cgtttgcggt
     2521 agatttttcg cctcttcttt tctgtttcgt tggcgaatcc gattcgaatc ttctatcttt
     2581 gtgattgaaa acaaattact gaatcagcca tgacgagaca cttagttccg gtatctatat
     2641 acctgtcgct gttgcttagc tgcaactcac cgaaagaata caaatccttt gatgaatacc
     2701 cttcctatga gggagacgat ctggagttgt tctattcccc cacgaaatcc gtgttcaccc
     2761 tttgggcccc gacggcggaa gaagtccgct tgaatcttta cgcctccggt gagggagggg
     2821 agcctatccg ccagttgccg atgaaatcct cggacaaggg tacgtggcgt atctccgtga
     2881 gcgaggatct gaaaggttcc ttctatacct tccagatccg tatcggcgat aaatggctgg
     2941 atgagactcc cggtatctgg gcgaaagccg tcggggtgaa tggaaaccgt gcggccgtga
     3001 tcgattgggc ggctaccgat ccggagggct gggaggcgga taaatctccc gagttgaaaa
     3061 gcttctccga tattatcatc tacgagatgc atcatcggga tttctcgatc gccgcgaact
     3121 ccggcgtgac gcataaaggt aagtttctcg ccttggcgga gaacggcacg aaaggtccgg
     3181 gcggcgtggc taccggcgtg gatcatctga aggagttggg cgttacccat gtccatatcc
     3241 ttccttccta tgattatggc tcggtggacg agacccgctt gcaagataat gtgtacaatt
     3301 gggggtatga tcccaagaac tataacgccc ccgaggggag ctattccacc gatccttaca
     3361 atcccgaggc tcgtattcgt gagttcaagg agatggtgcg ggggttgcac cggaatggta
     3421 tccgtgtgat catggacgtg gtttacaatc atacctttgt gggtgacggg tcgaatttca
     3481 gcttgaccgt ccccggttac ttctaccgtc ataaactgga cggaagctat tcggatgcct
     3541 ccggctgtgg taatgagacc gcttcggagc gggcgatggt acgccgctat atcgtggagt
     3601 ccgtgaaata ttgggccgag gaataccatg tggatggttt ccgtttcgac ttgatgggca
     3661 tccatgacgt agagaccatg aacgaggtaa aagccgagtt aaccaaacta gatccttcca
     3721 tcttcgtata cggcgagggc tggaccgcca gcgattcccc gctaccggag gatcagaggg
     3781 cgatcaaggt aaacgccccg aaactgaatg atgtggccgt atttagcgat gacctgcggg
     3841 atgctttaaa aggaagcgta ttcgagacta cacaggccgg tttcgcctcc ggaaagccgg
     3901 aaggtaacga ggagtctatt aagttcggta ttgtaggcgc tatccgccat ccgcaaatcg
     3961 actataacca aatattatat tgcaaagcgc cttatgcgaa caagcctacg caagtgatca
     4021 actatgtctc ttgccacgat gatctttgtt tgatggataa gttgaagctc tcggccccga
     4081 aagacgctac cccggatgag ttgatacgat tcggcaagtt ggcccagacc atcatcttca
     4141 cctcgcaagg agttcccttc atgcgggcag gagaggagtt gctgcacgat aagaagggcg
     4201 tacataacag ctatcaatcg cccgattcaa tcaatgagat cgactggtct ttgaaggcaa
     4261 aaaacaagga tgttttcaac tattacaagg atttgatcgc ccttcgtaag tcgcacccgg
     4321 ctttccgtat cgccacggcc gagggagtga gggaggccct tcaattccaa gaagtgaacc
     4381 agcccggtgt cgtagcgtat accttagggg a
//
LOCUS       DBMDTB010000177         4290 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_4815_length_4290_cov_11.473383, whole genome shotgun sequence.
ACCESSION   DBMDTB010000177 DBMDTB010000000
VERSION     DBMDTB010000177.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 4290)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 4290)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4290
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_4815_length_4290_cov_11.473383"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(822..896)
                     /locus_tag="ACZPB4_16505"
     tRNA            complement(822..896)
                     /locus_tag="ACZPB4_16505"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(859..861),aa:Pro,seq:ggg)
     gene            complement(933..1994)
                     /gene="aroB"
                     /locus_tag="ACZPB4_16510"
     CDS             complement(933..1994)
                     /gene="aroB"
                     /locus_tag="ACZPB4_16510"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HIR1099852.1"
                     /translation="MSEQKVVICKDLKSELQDFLSSLKYDKLFILMDTNTKEKCFPLV
                     EDIPAFQKAPILVMEAGDMNKGFVSLAQIWTALSNEGASRNSLLVNLGGGMITDMGGF
                     AGATFKRGIRTINIPTTLMASVDAAVGGKTGINFNGLKNEVGSFYPPLCVFIDCDFLR
                     TLDRDNILSGYAEMIKHGLISSMENYASVMLFDIDTMNYSYLNSLVGQSVAVKERIVE
                     EDPKEQGIRKALNFGHTIGHAFESLSFLKMRPILHGHAVAAGIVSELYLSHKLCGFPM
                     EKLSQVVYYIKEYYPALFFDCTDYDTLYELMTHDKKNEGGIINFTLLKNVGDVRINQS
                     VTKEKILESLDFYRESFGI"
     gene            complement(2149..>4290)
                     /gene="alaS"
                     /locus_tag="ACZPB4_16515"
     CDS             complement(2149..>4290)
                     /gene="alaS"
                     /locus_tag="ACZPB4_16515"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005866897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HIR1099853.1"
                     /translation="NKHDNFWEMGDTGPCGPCSEIHIDLRSDEERAAVSGADMVNKDH
                     PQVIEIWNLVFMQFNRKADGSLEPLPAKVIDTGMGFERLCMALQGKTSNYDTDVFQPI
                     IKVIAGMAGTTYGTDKQQDIAMRVIADHIRTIAFAITDGQLPSNAKAGYVIRRILRRA
                     VRYGYTFLDRKEAFMYKLLPVLIETMGDAYPELIAQKTLIEKVIKEEEESFLRTLETG
                     IRLLDKKMEETKAAGKTVLNGVDAFTLYDTYGFPLDLTELILRENGMEADIEEFNKAM
                     QKQKERARNAAAIETGDWITLKDGECKFVGYDLFECEAEILRYRQIKQKNKVLYQIVL
                     DQTPFYAEMGGQVGDTGWLIADDEKIDVIDTKRENNLPVHLVTKLPKDVTATFTAKIN
                     VKKRIQCECNHSATHLLHEALREVLGTHVEQKGSYVSPDSLRFDFSHFQKVTDEEIRK
                     VEILVGEKIRANFPLEEHRNMPIAEAKALGAMALFGEKYGDEVRVVKYGSSVELCGGT
                     HIPATGMIGSLRVIGESSIAAGVRRIEAVTAEGAEQFVYAQQDLIRELRALMNHMPNL
                     AQAMKKSIEENAEMKKQIEDYIREKSMRLKEEIVAKASESNGIKVMQFVGKANADAMK
                     NVAFQIKAETTDSFVFVAGIIDDNKCTLMLMLSDGLVKEGLHAGKIVKEAAKHIQGGG
                     GGQPHFATAGGKNMEGLSIAVGAVKEAVGVQ"
BASE COUNT         1178 a         1133 c          837 g         1142 t
ORIGIN      
        1 caactcttta attatccttc gccataccaa aacgactagt ctagaccatc atttagatct
       61 tgcgtttttg aagagggaaa acgggaggtt tgtttacgga atcggttgtt tcgtaaagga
      121 taggctatcc tattgataag aaagcgaata agggatgaaa aaaatagctc ggaagggttg
      181 caggtatcaa agaaacgcgt acctttgcaa atgacgaatt aaaacgatcg tttatactag
      241 ccgttttatt agataaatca gtccttgata ttattggtat gtattactaa agcctattca
      301 tatacatcat attctttaat gtacgtgtac atatataata taatttccaa aaatcctcct
      361 ctaggttaac gcatacttga tttcgcaggc cgtagaaggc tttccaagtg atcagttatt
      421 cacttcccga gccgttagtt agcggctata tatagccgct agttattcat tcgacaagcc
      481 gttagttatt cacttcagca gccaatggca ctctatcaaa cagctaggcc tccctactcc
      541 gataaacaat cgtgccccaa aagactttga actcacagag catgcaccga taagtcggca
      601 ctaagcaacc attaacagaa ataatggcta aaataggctg gaatgaccgc actaaattca
      661 aacggaaata tatcaatttt aatctattgt catgatttaa ggctatcccc catgaatatc
      721 ggatgagtcg gaatttctac tgcctcattg ttttaggaaa gtgatagaga gcaaaaaaag
      781 gagttaagcc atagacttaa ctccttttct ctcagcttta gtcgggatga ctggattcga
      841 accagcgacc acacgccccc cagacgcgta ctctaaccgg gctgagctac atcccgcttt
      901 tattttacgg gtgcaaaggt agtttttttc cgttaaatgc caaaactttc acgataaaaa
      961 tcaagagact ccaagatttt ttccttggtg accgattggt tgatacggac atcccctaca
     1021 tttttcagta aagtgaagtt gatgataccg ccctcattct ttttatcatg tgtcattaac
     1081 tcatataagg tatcgtagtc cgtgcagtca aagaagagcg ccggataata ctcttttata
     1141 taataaacga cttgactcaa tttctccatc gggaagccac acagcttatg cgagaggtaa
     1201 agctcgctca cgatacccgc cgctaccgca tgaccatgca agatcggacg cattttcagg
     1261 aaagacaagc tctcgaaagc gtggccgatc gtatgaccga aattcaatgc cttacgaata
     1321 ccttgttcct tgggatcttc ctctacgatc cgctctttca cggcgaccga ctggcctacc
     1381 aaactattca aatacgaata attcatggtg tcgatatcaa aaagcatgac agacgcataa
     1441 ttctccatcg aactaatcaa cccgtgcttg atcatctccg cataaccgga aaggatatta
     1501 tcgcgatcca acgtgcgcaa aaaatcgcaa tcgatgaata cacacaaggg gggataaaaa
     1561 gaaccgacct cgttcttcaa cccattgaag tttatacccg tcttaccgcc aaccgcagca
     1621 tcgacggacg ccatcaaggt cgtagggata ttgatcgtac ggatgccccg cttgaaagta
     1681 gcgccggcaa aaccacccat atccgtaatc ataccgccgc ccaaattcac cagcaaggag
     1741 ttacgggaag ccccctcatt cgacaaagct gtccatatct gggctaatga gacaaaaccc
     1801 ttattcatat cacccgcttc catcacgaga atcggcgcct tttgaaaggc cggtatatcc
     1861 tctaccaagg gaaaacattt ctctttggta ttcgtatcca taaggatgaa caacttatcg
     1921 tattttagag aggagagaaa atcttgcagt tccgatttca ggtccttgca aataaccact
     1981 ttttgctctg acatatcttt tttatttaaa accttagacc acaaaggtaa aacatgtatt
     2041 ccgattatca aaacgacata aaaaaattcc ttcggatgga attcttattc gatccgaagg
     2101 aatctatcat taagtccgaa agaaaagtca atttcttccg aaccgatttt actgtactcc
     2161 aacagcctct ttcacagcgc caaccgcaat ggaaaggccc tccatgttct taccgccggc
     2221 cgtagcgaaa tggggttgtc caccaccacc gccttggata tgcttagcgg cctcttttac
     2281 gatcttaccg gcatgcaagc cctctttcac caaaccatcg cttaacataa gcatgagcgt
     2341 gcatttgtta tcgtctatga taccggcaac aaagacaaag ctatcggttg tctccgcctt
     2401 gatctggaaa gccacgttct tcatagcgtc cgcatttgcc ttaccaacga actgcataac
     2461 cttgatacca ttgctctccg aagctttcgc cacgatctcc tctttcaaac gcatagactt
     2521 ctcacggata taatcctcga tctgtttctt catctcggcg ttctcctcga tagacttttt
     2581 catcgcttgc gccaaattcg gcatatggtt catcaacgca cgcaactcac ggatcagatc
     2641 ttgctgggca tatacgaatt gctcggcgcc ctcggccgta accgcctcta tacgacggac
     2701 tcctgcggcg atagagctct ctcctatcac gcgcaaagaa ccgatcatac cggttgccgg
     2761 gatatgcgta ccaccacata gctccacgga gcttccgtat ttcacgacac gtacctcatc
     2821 gccatatttc tcaccgaaca aagccatagc ccctagcgcc tttgcttcgg cgatcggcat
     2881 attgcgatgc tcttccaacg ggaagttcgc acggatcttc tctccaacca atatttccac
     2941 cttacggatt tcctcgtccg tcactttctg gaaatgagag aagtcgaaac gtaaagaatc
     3001 aggcgaaaca tacgaacctt tctgctctac gtgcgtacct aatacctcac gcaacgcctc
     3061 atgcaaaagg tgcgtggcag agtggttaca ctcacactgg atacgctttt tcacgttgat
     3121 cttcgcggta aatgtagccg ttacgtcctt cggtagttta gtaaccaaat gaaccggcaa
     3181 attattctct cgtttcgtat cgatcacgtc gatcttctcg tcgtcggcga tcaaccaacc
     3241 cgtatcaccg acctgtccac ccatttccgc atagaacggg gtttgatcca gaacgatctg
     3301 gtataatact ttattctttt gtttgatctg gcgataacgc aagatctctg cctcgcattc
     3361 gaacaaatca taacccacga acttacattc accgtctttc agcgtgatcc agtcgcctgt
     3421 ctcgatagcg gcggcgttac gggcacgctc tttctgcttc tgcatagcct tattgaactc
     3481 ctcgatatcg gcttccatgc cgttctcacg aagaatcaat tccgtcaagt ccaacgggaa
     3541 tccgtaggta tcatataatg taaaggcatc tacgccattc aagaccgtct tgcccgcagc
     3601 cttcgtctcc tccattttct tatccagcaa acggataccg gtttccaagg tacgaaggaa
     3661 agattcttcc tcctccttga taaccttctc aatcaaggtt ttctgagcga tcaattccgg
     3721 ataagcgtcg cccatcgtct cgatcaatac gggcaaaagc ttatacataa acgcttcctt
     3781 gcgatccaag aacgtataac cgtaacgaac agcacgccgc aagatacgac ggattacata
     3841 accggcctta gcgttggaag gcaactgtcc gtccgtgata gcgaaagcga tcgtacggat
     3901 gtggtcggcg atcacacgca tggcgatgtc ttgctgttta tccgtaccgt aagtcgtacc
     3961 cgccattccc gcaattacct tgataatcgg ttggaatacg tccgtatcat aatttgaggt
     4021 cttaccctgc aatgccatac acagacgctc gaatcccata ccggtatcga tcaccttagc
     4081 cggcagcggt tccaaagaac catcggcctt acggttgaat tgcataaata caagattcca
     4141 gatctcgatt acctgcggat gatccttatt taccatatcg gcgccgctga ccgccgcacg
     4201 ctcctcgtcc gaacgaaggt cgatatggat ctcggaacag ggaccgcaag gacccgtatc
     4261 ccccatttcc cagaagttat catgtttgtt
//
LOCUS       DBMDTB010000178         4119 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_5068_length_4119_cov_10.361623, whole genome shotgun sequence.
ACCESSION   DBMDTB010000178 DBMDTB010000000
VERSION     DBMDTB010000178.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 4119)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 4119)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4119
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_5068_length_4119_cov_10.361623"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..197)
                     /locus_tag="ACZPB4_16520"
     CDS             complement(<1..197)
                     /locus_tag="ACZPB4_16520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF418 domain-containing protein"
                     /protein_id="HIR1099854.1"
                     /translation="MEHALQSRPRIEVVDALRGFAVMAIILLHNIEHFNLYNFPEATT
                     DFMKALDKGVWDTLFFLFSGKA"
     gene            complement(568..3054)
                     /locus_tag="ACZPB4_16525"
     CDS             complement(568..3054)
                     /locus_tag="ACZPB4_16525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HIR1099855.1"
                     /translation="MKEQSGHITSKVILGYILLITIAVCSVAYIYNIVEKVAEEDEPD
                     HQARRKVYLVTNTLSLLYESEALGQLVGMPQNEFRHFNRTLNKAHNNMDSLRTLVTDS
                     MQLLKIDTIDILLERKRWNTRRLLETWQEANTERLYTENIEKIIAVRDTIVNEVQVQE
                     RVEVKQDTVVVPRKKRGFFKRLADVFSPGKEDTSIVVNTTREIVTDTLVNAYNPTDTI
                     VSVLKSIQDSVAWQRQQLMDQLLERASNLRYNNSVITREINQMLRNIEEEEMEASLER
                     VYKKQVLLRETSHLIAGIAIVSVVIAFLFLFFISRDISRSKYYRMQLEKAKQVAESLL
                     RSREKLMLTISHDIRAPLSSIIGYIELLLRRHPDERQQYYLENMKGSSDHILSLVNDL
                     LDFQRLESGEMEVHSVPFRVPVLFDEIYTSFQPIAEAKGLRFVLNLKPEETGQVYMGD
                     PIRIRQVVGNLLSNAIKFTEAGRVVLLVSLQKLSIINFQLSITVSDSGPGIPKEEQER
                     IFGEFTRLADTEEVEGFGLGLSITRKLLSLMNGTLALDSTPGKGSDFTILLPLPLADN
                     QSLPDVTAEAPDAGEAEALPLFEGQDVYCLLVDDDPLQLALTEELLKQSHVQVVGCTN
                     PHNVLELLRNTVFNAIITDIQMPTLDGYHLLERIRTSGIPGTDEIPVIALSASIAKEH
                     EHYLEAGFTGFLNKPFTAAQLISLLNELLTLHLEARSELNFSSLTAFAGEDPEASASI
                     LKTFSEETRKSIDLLRDALEGKDREEASRISHKLIPLFTMLGANSLVQHLRILEKNDE
                     ELTDSGWYHLLGEVIEQALAIVKDAESAIG"
     gene            complement(3070..>4119)
                     /locus_tag="ACZPB4_16530"
     CDS             complement(3070..>4119)
                     /locus_tag="ACZPB4_16530"
                     /EC_number="2.7.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_process: GO:0009244 - lipopolysaccharide core region
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:1900727 - osmoregulated periplasmic glucan
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase"
                     /protein_id="HIR1099856.1"
                     /translation="EGKREIYVLVVGETSRAMEWSLYGYERKTTPRMEALDGLVHFTD
                     VVTQSNNTHKSVPIILSAASAENYGVLYDEKSIVTAFKEAGFRTLVIANQKLTTSMIG
                     AFYREADTFIDMSAFNTGSTLTSLHDAAILPYLKKELDKEDGNLFVVLHTYGSHFNYH
                     ERYPKEFRFYRPDKAEGIRASYKKELRNAYDNSIHYTDYVLGEIVDMLAKTNAPASML
                     YLSDHGEDIFDDSRARYLHASPIPTYYQLHIPYVIWFSKAYRESYPQKYLEAQAHETY
                     PVSTNSVFHTMLDIAGVRTPVADSTFALTNRAFKVRDRMYLGDHDDPIPFWKVGLKKQ
                     DFEMMDKWDIAYDRN"
BASE COUNT         1068 a         1066 c          930 g         1055 t
ORIGIN      
        1 gccttcccgg aaaagaggaa gaacaaggta tcccataccc ctttatccaa ggctttcata
       61 aaatcggtag tagcctccgg aaaattatac aagttaaaat gctcgatatt atgcaatagg
      121 ataatagcca taacggcaaa tcctcgtaat gcgtcgacca cctcgatacg aggtcgggat
      181 tgtagtgcgt gttccatgat atgattcagt agattttatt atttcgtggc aaaagtaacg
      241 aaactaaata gaaaaagcat cctcgaaagg atgccttttt cttttgcaga cttaaattga
      301 atactcagga cttaatcttt cgccatgaat aaattcatga cttttgtttt taacggttta
      361 aatgtagaaa cgcccacttg cgatttcatt aaatagatag cgaatatcgt gccaaagcca
      421 gcgaaacgca cgataatgaa tatctaacta cttatccttt aacaagtaat agataaattt
      481 tgtttctata aagtggaatt ttatttcaaa agcatgggga aaggcattcc acggatgggt
      541 atttattcca caccggattc cacaagatta cccgatggcg gactccgcat ccttcacgat
      601 agcaagcgct tgctcgatta cctcgcccag caggtggtac cagccggaat cggtcagttc
      661 ctcatcattc ttctccaaga tccgcaggtg ttgtaccaat gaattggccc ccagcatcgt
      721 gaacagggga atcaacttat gagatatccg ggaggcttcc tcccggtctt ttccctctaa
      781 cgcatcccga agtaagtcga tgctcttgcg ggtttcctcc gagaaggttt tcagtataga
      841 ggctgaggcc tccggatcct ctccggcaaa agcggtcaac gaagagaaat tcaactcgct
      901 ccttgcctcc agatggagtg tcagcaactc attcagcaag gagattaatt gggcggcggt
      961 aaacggcttg ttcaagaaac ccgtgaaacc agcctccaga taatgctcgt gctccttggc
     1021 gatactggca gatagggcga tcaccgggat ctcatccgtt ccggggatac cggacgtacg
     1081 tatccgctcc agtaaatgat agccatccag cgtcggcatc tgtatatcgg tgataatggc
     1141 gttgaatacg gtgttccgca atagctcgag gacgttatgc ggattcgtac aacctaccac
     1201 ctgcacgtga ctctgcttca agagttcctc cgtcaaggcc agttgtagag gatcgtcatc
     1261 taccagaaga caatagacat cttgcccctc aaacaagggt aaagcctcgg cctcaccagc
     1321 atccggagcc tccgccgtta cgtccggcaa agattgatta tcggccaagg gaagaggtag
     1381 caagatcgtg aaatcactgc ctttccccgg ggtactatcc aaagcaagcg taccgttcat
     1441 caaggacaga agcttacggg tgatggagag gcccagaccg aaaccttcca cctcttccgt
     1501 atcggcaagg cgagtaaact ccccgaatat ccgctcttgt tcctctttcg ggatgcccgg
     1561 accggaatcg cttacggtaa ttgataattg aaaattaata attgaaagtt tttggaggga
     1621 gacaagtaaa acgactcgcc ccgcttccgt gaacttgata gcgttagata agaggtttcc
     1681 tacgacctgc cggatacgga tcgggtcgcc catataaact tgcccagtct cctcaggttt
     1741 caggttcaag acaaaccgca agcctttcgc ctccgctatc ggctggaagc tggtatagat
     1801 ctcatcgaac aagactggga cacggaaggg aacgctatgc acctccatct cgccggactc
     1861 caaccgctgg aaatccaaca ggtcgttcac caaggaaagg atatgatccg aggaaccttt
     1921 catgttctcc aaataatatt gctgacgctc gtccggatgg cggcgtagca aaagctcgat
     1981 atatccgatg atggaagaaa gcggagcccg tatatcgtgg ctgatcgtca acatcagctt
     2041 ctcacggctt cgcaataagc tctcggcgac ctgtttcgcc ttttccagtt gcatacggta
     2101 atatttactt cgtgagatat cccgtgagat aaagaagagg aacagaaagg cgattaccac
     2161 ggagacgatc gcgattccgg cgatcaaatg ggaggtctcc cttaatagta cctgcttctt
     2221 atagaccctt tccagcgacg cctccatctc ctcctcctcg atattacgga gcatctggtt
     2281 gatctcccgg gtaatcacgc tattgttata ccgtaagtta gaggcccttt ccaacaactg
     2341 atccatcagt tgttgccgtt gccaagccac actgtcttgg atgcttttca gcacgctaac
     2401 aatcgtatcg gtcggattat aagcgttcac caacgtatca gtaacgatct cccgggtcgt
     2461 gttcaccacg atgctggtat cttccttgcc gggagagaac acgtcggcca gacgcttgaa
     2521 gaatccccgc ttcttacggg gaactaccac cgtatcttgc ttgacctcta cccgctcttg
     2581 tacctgcacc tcgtttacga tcgtatcccg gacggcaatt attttctcga tattctccgt
     2641 ataaagacgc tccgtgttcg cttcctgcca agtctcaagc aaacgacggg tattccatcg
     2701 cttacgctcc agcagtatgt cgatcgtatc tattttcagg agttgcatgg agtccgtcac
     2761 caaggtcctc aacgaatcca tgttattatg ggccttattc aacgtacgat tgaagtggcg
     2821 gaactcgttc tggggcatgc ctaccaactg ccccaatgcc tcgctctcat agagcaggga
     2881 gagggtattg gtgaccaaat acaccttccg gcgtgcctga tgatccggct catcctcctc
     2941 ggccactttc tctacgatat tataaatgta agcgaccgag cagactgcaa tggtaatcag
     3001 caaaatatag cctaatatca ccttgctagt aatatgtccg ctttgctctt tcatacggtt
     3061 gagatcagtc taatttctat cgtaagcgat atcccattta tccatcatct caaaatcctg
     3121 ctttttcaag ccgactttcc agaatggaat cgggtcgtca tggtctccca gatacatacg
     3181 gtcacgtacc ttgaaggcac gattcgttaa ggcaaacgtg gaatcggcca ccggagtccg
     3241 cacaccggct atatcaagca tcgtatggaa tacgctgttc gtgctaaccg gataagtctc
     3301 gtgtgcctgc gcttccagat atttctgggg atatgactcc cggtaagcct tcgagaacca
     3361 gatcacatac gggatatgca actggtaata ggtcggtatc ggagacgcat gcagataacg
     3421 ggctctggaa tcatcgaaga tatcctctcc atgatcgctt aagtaaagca tggatgccgg
     3481 agcatttgtc ttcgccaaca tatccacgat ttcccccagc acgtaatctg tatagtggat
     3541 ggaattatca taagcgttcc gtaactcctt tttatacgag gcacgaattc cctccgcctt
     3601 atccggccta tagaaacgga actccttcgg ataacgttca tggtaattaa aatgcgagcc
     3661 ataagtatgc agtactacga aaagattacc gtcctcttta tccagttcct tctttagata
     3721 aggcaggatc gccgcatcgt gcaaggaggt tagcgtagaa cccgtattaa atgcactcat
     3781 atcgataaag gtatctgcct cccggtaaaa agcgccgatc atcgaggtcg ttagtttctg
     3841 gttggcgatc acgagcgtac ggaaaccagc ctctttgaaa gcggtcacga tacttttctc
     3901 gtcgtaaagg actccataat tctcggcgct ggcagcggac aggataatgg ggacactttt
     3961 atgcgtatta ttcgattgcg tcaccacatc cgtgaaatgc accaatccgt ctaaagcctc
     4021 catacgggga gtcgtcttgc gctcgtatcc gtaaaggctc cattccatag cacgggaggt
     4081 ctctcccact accaagacgt agatctcccg ttttccctc
//
LOCUS       DBMDTB010000179         3978 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_5276_length_3978_cov_9.819706, whole genome shotgun sequence.
ACCESSION   DBMDTB010000179 DBMDTB010000000
VERSION     DBMDTB010000179.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 3978)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 3978)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3978
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_5276_length_3978_cov_9.819706"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..186
                     /locus_tag="ACZPB4_16535"
     CDS             <1..186
                     /locus_tag="ACZPB4_16535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4469 domain-containing protein"
                     /protein_id="HIR1099857.1"
                     /translation="NTKSEIIIQIPQLAEGQYWLSVTTQAGANYGLVKDPRTYKFPIL
                     LTVGAGGGGDSESPDEI"
     gene            360..3860
                     /locus_tag="ACZPB4_16540"
     CDS             360..3860
                     /locus_tag="ACZPB4_16540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat protein"
                     /protein_id="HIR1099858.1"
                     /translation="MKTNLLRIGLRLSLVVIALLCGVYLAWGQENTKVMHKIYTNTYG
                     NVTIDCPSEVEDGGSFTFKIATSTGAYRLAISQAGKNFRDFSWDDSQNANVAKNITGT
                     ILIEVVEHTEIMIGEERYMLEECSAMLPPSQTQPTSSSIVLKSVVTAKGKHYSLNSYS
                     GAYNRYANITSITLPNNKYFINPYAFSIQAGLTEIHAKAIDPKNYHIMEGAFGEKDLS
                     GITLYVPAGSKADYAASTPWNQFKEILEEPLPKKYPVYVVGYGVASTDAPDSIARGQS
                     LTVNITLEPGFKSFEPSVITIPGEEVNKDVVIQVSTHTENVLSGISYSMSTTQVNAFC
                     HGFLDTPQKEVTIPEVVTVGSNSYKVEYIVADAFKNQTSLEKLTLEGNTGIDRRAFSG
                     CTALKEIHCISPEPRNISDEDAFEGVDKDACVIFVPAGASAAYKAAYVWKDFKNIREE
                     GTYSITRTGFEGVAYYGPDLVVDGSRLEARLTPESGYVLGIGDITVTMGGKKLDPMSK
                     EFFYGTFGKDTLTIETVTGDVTITAKARKISGDPFVLGDLTYRITRDAAVEVAGVKED
                     AYTKGRSYVIPSSLEYEGNNYTVTGIGPKAFSGRIMESIMIPSSVEEVGTESFLDAQA
                     DEIHIQRSTPPSTVNGSFNILDKNKCRIYVPKGALAAYHTATWDWLGFPYILEEGDKY
                     FDVDFELTGLTVKPFQPEIAISGRSVSFILVPDSGSFLPDSIEVWYPTGLEPCEYDAK
                     TGKVTIATVKGNLTIKAKAIGALLPDKDTDITIGKDSTYTDGSTTGSKFNGVIGNDEE
                     LTRVKSLKIDTEDGKVTGITFKSLIVGSGSSTSQSVTVAETSNIEITLDGNNNLGKVL
                     NQGSTRLLPGENTLLDALVENEGIFIDETGLLDAVTGPAGLTIAQRPEKAPRIEMGFS
                     TLLKVEASAEEEANLSYIWEKFDSENNSWKQVKPEVQRTKALSSLRSDVLSTNEDAQL
                     EVSEAGKYRCLVSNTVNAVNSTLTAYSEVSIASSTPDPTVTFSVTLPSVEGASLNPSA
                     GTYSVEAGGSFSFSLTLDTDYDQSTPMVKVGDKLIEPTSDGKYEIKNINSDITISITG
                     IVKNVTVGNAEVESNALKVWGSNGVLHIRSAHAGTAYLVTFGGQLYKAITLPVGETMI
                     TIPQGSYIIRIENQSYKIRF"
BASE COUNT         1123 a          826 c          991 g         1038 t
ORIGIN      
        1 aacaccaaga gcgagataat tatccagatc ccgcaactcg ccgaggggca gtactggctg
       61 agcgtcacta cgcaggcggg ggcgaattac ggcttggtga aggatccccg tacctataag
      121 ttccccatcc tcctgacggt aggtgccgga ggcggaggcg atagcgaaag cccggacgag
      181 atctgataag gcagagagcc tcatctatga gggctgataa agcctaggct ctcacccctc
      241 atagacgagg ctctctcatg gttcatggcc taggctctct caccggtcat aaacgggaag
      301 ctatgagcat acccgtgaac gaatgttaag actattattc actttaaatt atatcgctta
      361 tgaaaacaaa tttactacga atcggtttac ggctgtcgct ggtggtgata gcccttttgt
      421 gtggtgtgta tcttgcttgg gggcaggaaa atacgaaagt gatgcacaag atatatacta
      481 atacttatgg taatgtcacg attgattgtc cgtcagaggt tgaggatgga ggtagtttta
      541 cttttaaaat agcaacatca acaggtgctt atcgtcttgc tatatcacaa gcagggaaga
      601 attttaggga tttctcatgg gatgattccc aaaatgctaa tgtggcgaag aatattactg
      661 gaacgatctt aattgaggtt gttgagcata cggaaataat gattggagag gagaggtata
      721 tgcttgagga atgcagcgct atgcttcctc cttcacaaac tcaaccgact tcatcaagca
      781 tagtattaaa gagcgtggta accgcaaaag gaaagcacta tagtttgaat agttattccg
      841 gtgcctataa tagatatgct aatataacat caataacatt gccgaacaac aagtatttta
      901 tcaatccata tgcgttttcc atacaggctg gtttgactga gattcatgcg aaagctatag
      961 accccaaaaa ttaccatata atggagggcg ctttcggaga gaaagatttg agtggaatca
     1021 cgctttacgt accggctggc agtaaggctg attatgccgc cagtacccct tggaatcagt
     1081 ttaaggaaat tttggaggag ccgcttccca agaaatatcc ggtttatgtt gtgggttatg
     1141 gagtagcgtc tactgatgcg ccggattcaa tagctcgagg gcaatccttg accgtgaata
     1201 ttacgctgga acccggattt aaatcttttg aacctagcgt aataactatc ccgggtgagg
     1261 aagtgaataa agatgtcgtt atacaagtct ctactcatac ggaaaatgta ttgtctggaa
     1321 tttcttatag catgagtact actcaagtaa acgcattttg tcatggcttc ctagatactc
     1381 cccagaaaga agtgaccata ccggaagtgg tgactgtcgg gtctaattct tataaggtag
     1441 aatatatcgt ggctgatgcg tttaaaaatc aaacctcact cgaaaagctt actctagaag
     1501 gaaacactgg tattgatcgg agagcattct ctgggtgtac cgccttaaaa gagattcatt
     1561 gtataagtcc tgaacccaga aatatttctg atgaggacgc ttttgaagga gtggataaag
     1621 acgcatgtgt catctttgta cctgccgggg cttccgctgc ctacaaagcc gcctatgtct
     1681 ggaaggactt taagaacata agggaggagg gcacatactc catcacccgt accggatttg
     1741 agggagtcgc ttattatggc cccgacttgg tggttgatgg ctcccgactg gaagcgagac
     1801 tcacgcccga gagtggctat gtattaggca taggagacat caccgtcacc atgggaggca
     1861 agaaactgga tcctatgtcg aaggaattct tctatggtac attcggtaag gataccttga
     1921 ctatagaaac cgttaccggc gacgtgacga tcactgcgaa agctaggaaa attagtgggg
     1981 atccttttgt ccttggtgac cttacctatc ggattactag ggatgcggct gtcgaggttg
     2041 cgggtgtaaa agaggatgcc tatacgaaag gtagatcgta cgtaatcccc tcttctttgg
     2101 aatatgaagg gaataattat actgttaccg gtatagggcc taaggcgttc agcggtcgta
     2161 tcatggaatc cataatgatc ccgagtagtg tggaggaagt aggaacagag agtttccttg
     2221 acgcacaagc tgacgagatt cacattcaac gttctacgcc accttcaacc gttaatggct
     2281 cattcaatat cttggataaa aacaaatgta gaatctacgt gcccaaaggg gcccttgccg
     2341 cttatcatac cgctacttgg gattggctag gttttcctta tatcttggaa gaaggtgata
     2401 aatatttcga tgtggacttt gagttgacag gacttaccgt aaagcccttc caaccggaaa
     2461 tagctatatc cgggaggtcc gtgtctttca ttttagttcc ggatagcggt agttttttgc
     2521 cggactcgat cgaggtatgg tatcctacag gtctggagcc ttgcgagtat gacgcaaaaa
     2581 caggcaaggt cactatcgct acggtaaaag ggaacttgac tatcaaagcc aaagcgatag
     2641 gagccttatt gccagataag gacactgata ttacaatcgg aaaagattct acctatacgg
     2701 acggcagtac gacaggcagt aagttcaatg gagtcatcgg aaacgacgag gaattaacaa
     2761 gagttaaatc cttgaaaata gatactgagg atggaaaggt taccggcatc acgtttaaaa
     2821 gcttgattgt tggttccgga agttctacgt cacagagtgt taccgttgcc gagacatcca
     2881 atatcgagat cacgttggat ggcaataata acttagggaa agtattgaac caaggaagca
     2941 cacggttact acccggcgaa aataccctgt tggatgcgtt ggtggaaaat gagggtatct
     3001 tcattgatga aaccggtctg ttagatgccg taacggggcc tgctggcctt actattgccc
     3061 aacgaccgga gaaagcgcct aggatagaga tgggtttctc cacgcttcta aaagtcgaag
     3121 cgtcggctga ggaagaggcg aatctttcct atatatggga gaaatttgac agcgagaata
     3181 atagctggaa gcaagtgaag ccggaagtac agcggacgaa ggctctctcc tctcttcgct
     3241 cggatgtctt aagtacgaat gaagatgcgc aactggaggt ctccgaggcc gggaagtatc
     3301 gttgtcttgt ctcgaatacg gtaaatgctg taaattctac tctgaccgct tattcagagg
     3361 taagcattgc ctcttccaca ccggatccaa cagtgacctt tagtgtgacc cttccatccg
     3421 ttgaaggtgc ctcgttgaat ccttccgctg gaacttattc cgtggaagcg ggcggtagct
     3481 tctccttctc tcttacgctc gatacggact acgatcaatc tacccctatg gtaaaagtag
     3541 gcgataagct gatcgagccg acctctgatg gcaagtatga gatcaagaat atcaactctg
     3601 atataacaat atctattacc gggatcgtaa aaaacgtcac cgttggcaac gccgaggtag
     3661 aatccaatgc cttgaaagtc tggggatcga acggggtatt gcatatccgg tccgctcatg
     3721 cgggtacggc ttatctagtg acattcggcg gtcaattgta taaggcgata accttacctg
     3781 ttggtgagac aatgataacc atcccgcaag gttcctatat catccgtatc gaaaaccaat
     3841 cctacaagat ccgcttctag ccattcttga ggaatcatag gaaggcgagt catttgcgag
     3901 tggctcgcct ttcttgttta ataaatctta atatttaccg gggatataag tatcgtaagc
     3961 cattagaaag tatattca
//
LOCUS       DBMDTB010000180         3937 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_5335_length_3937_cov_12.361314, whole genome shotgun sequence.
ACCESSION   DBMDTB010000180 DBMDTB010000000
VERSION     DBMDTB010000180.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 3937)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 3937)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3937
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_5335_length_3937_cov_12.361314"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..396)
                     /locus_tag="ACZPB4_16545"
     CDS             complement(<1..396)
                     /locus_tag="ACZPB4_16545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage integrase SAM-like domain-containing
                     protein"
                     /protein_id="HIR1099859.1"
                     /translation="MKRGRKKKLAISLMDYMGKRRDMKRQLKKEGTAELYEVAVRHFL
                     RFVKNPGFCLADLNRALVIDFITYLQGKGLATNTVNTYISSLRALYNMACQEALIPAS
                     YYPFENLKLRRAMTARRAIPASLFQQIAQI"
     gene            515..1879
                     /locus_tag="ACZPB4_16550"
     CDS             515..1879
                     /locus_tag="ACZPB4_16550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HIR1099860.1"
                     /translation="MANNRVTFGSKLGVVLATVGCAVGLGSVWRFPYMLGANGGAAFL
                     LVYILFMIFLGIPVMITEFFIGRHSRSNTVGSFKKMAPGTKWCWIGYNGILAAFLILS
                     YYSVVSGWTLEYVWQTLSGRLYGQPDIDYTADFQDFASNVFRPIFWMGAFIGLTHFVI
                     VSGVEKGIERASKIMMPLLFLILLIMCVRSVTLPNAEAGLLFLFKPDFSKLTSSVVLS
                     ALGQAFFSLSLGMGCLITYSSYFGKDTNMQATAWQVTIINTLVAVLAGIMIFPAVFSF
                     GITPSAGAELVFITLPNVFGQLPLSGLWSCIFYILLAMAALTSTISLHEVATAYVLEE
                     FHMTRKKAALIVSLGVFFLGIFSSLSFGVMKGFTIGGLAFFDALDYLTAKIMLPLGGM
                     LTCIFVGTRVDKKVLKAELTNEGTLKFRLFGAYVFFMKYVAPIAIGIVFLNELGILKW
                     ITGK"
     gene            1957..2685
                     /locus_tag="ACZPB4_16555"
     CDS             1957..2685
                     /locus_tag="ACZPB4_16555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HIR1099861.1"
                     /translation="MKWRDLLYFSKGERQALTLLLSLIAMAWIAIIGTDFYRSQFQTV
                     PLANTGIKQDSSRIYSNKTPSNFIRKEKESHSNETKIPSEWKSKRIRRESKPHFPSYP
                     QAEKWPQGTVVELNSADTTALKMVPGIGSVFAKRIIKYRDLLGGFYSVEQLGEVYGID
                     EERYEAMKSWFSVDPSVISHLFVNQLSAKELASHPYVSYKQARIIEKMIRKKGKLQGW
                     EDLSLLEEFPEHEQQRLRYYLSFH"
     gene            2721..3485
                     /locus_tag="ACZPB4_16560"
     CDS             2721..3485
                     /locus_tag="ACZPB4_16560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HIR1099862.1"
                     /translation="MIYLKQVKLLDPDLVAGNPEELKYPYKAPAVRFTESFIFRKPVT
                     FLVGENGAGKSTLLEAMMSKYEERDEEEPGMLYDGTEAYKIYANVLPEHIKLIETRKP
                     EKHFFFRAESFFNHAAELDRQAQLELRKYSKIYAYKAYGGRSLLEQSHGESFLSAFLN
                     YASRNTLFILDEPEAALSPQRQLALLVRIHELVNNGCQLIISTHSPILMAYPNADIYA
                     IDDTGAHITPYEETEHYQLTKYFLTHTEQMMKELLG"
     gene            complement(3488..>3937)
                     /locus_tag="ACZPB4_16565"
     CDS             complement(3488..>3937)
                     /locus_tag="ACZPB4_16565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HIR1099863.1"
                     /translation="EWMLVSAGDKEKFNMMTASWGGVGVLWNRPVVFAFIRPERYTRE
                     FIDAKNEFTITFLGPEHRKAHSICGSKSGREIDKVAATGLTPFFTEAGNPVFEEARLT
                     LECKVVYKSEIEEAKFLDPSVFPRWYDEKNGNAHIVYIAEIVNAWEK"
BASE COUNT         1062 a          936 c          861 g         1078 t
ORIGIN      
        1 gatctgagcg atttgctgga acaaagatgc gggaatcgca cgcctcgccg tcatcgcacg
       61 ccggagtttc aaattctcaa acggataata tgacgcagga atcaacgcct cttggcaagc
      121 catattataa agcgcccgca aactactgat atacgtattt accgtattag tagctaatcc
      181 ttttccctga agatacgtga tgaaatctat caccaacgca cgattcaaat cggccaaaca
      241 gaaccccggg ttcttcacga atcttaaaaa atgccttacg gccacctcat acaactcagc
      301 tgtcccttct ttctttaact gccgtttcat gtctcttcgt tttcccatat aatccatcaa
      361 tgagattgct aactttttct tacgtcctcg tttcatactc ctttcactaa attatttata
      421 ctttacacga acaaattaat tcaaattatt acttttgctc ccgaaaataa gaaaataggt
      481 aacaattaaa agcataaaag caacaataaa taatatggca aacaatcgag tcacattcgg
      541 tagtaaattg ggcgtagtac tagctaccgt aggatgcgcc gtcggattgg gaagcgtatg
      601 gcgcttcccg tatatgctgg gagcgaacgg aggtgcggcc ttcctactgg tctacatact
      661 tttcatgata ttcttgggca ttccggtaat gataaccgag tttttcatcg gccggcattc
      721 ccgcagcaat acggtgggtt ctttcaagaa aatggctccc ggtacaaaat ggtgctggat
      781 tgggtacaac ggtatcttgg ccgcattttt gatcttaagt tattactcgg tcgtctccgg
      841 ttggacgctt gaatatgttt ggcaaacgct aagtggccgt ttgtatggac agccggatat
      901 agactatacg gccgattttc aggatttcgc ttccaatgtc ttccgtccga tcttttggat
      961 gggcgctttt atcgggttga ctcacttcgt gattgtctcg ggcgtagaga aaggcatcga
     1021 acgggcctct aagatcatga tgccgctttt attcttgatc ttgctgatca tgtgcgtacg
     1081 ttccgtgacc ttaccgaacg ctgaggccgg attgcttttc cttttcaagc cggattttag
     1141 caaattgact tcctcagtgg tcttgagcgc actaggacag gctttcttct ctttgagttt
     1201 gggtatgggc tgcctgatca cttactcctc ttacttcggg aaagatacga atatgcaggc
     1261 caccgcttgg caggtgacaa tcattaatac gcttgtcgcc gtattggccg gtatcatgat
     1321 attcccggcg gtattcagtt tcggcatcac cccttccgct ggtgcggaac tcgtgtttat
     1381 cacgttaccg aacgtatttg ggcaattacc gctgagtggc ttgtggtcct gtatttttta
     1441 tatcttgcta gcgatggcgg cactgacttc cacgatctct ttacatgagg tagctacggc
     1501 ctacgttctt gaggagttcc atatgacacg caagaaagcg gctttgatcg tttccttagg
     1561 agtctttttc ttaggtattt tcagttcact ctcattcggg gtgatgaaag gattcacgat
     1621 tggaggcttg gcctttttcg acgcgctgga ttacttgacc gccaagatca tgctaccgct
     1681 gggaggtatg ctcacttgta ttttcgtagg tacacgtgtc gataaaaaag tattgaaagc
     1741 cgagttgacc aatgagggga ctcttaagtt ccgtcttttc ggcgcttacg tattctttat
     1801 gaaatacgtg gccccaatcg ccatcggtat cgtatttttg aacgaattag ggatcttgaa
     1861 atggattacc ggtaaataat accgagaatt ccttgtcaat agaaacggaa cttctacctt
     1921 tgtcggtgga agttccacaa atcaaaacat aagactatga aatggcgtga tttactttat
     1981 ttctccaagg gggaaaggca ggctcttacc ctactccttt ccttaatagc gatggcatgg
     2041 atcgcaatta tcgggacgga tttctaccgt tcccaatttc aaacagtccc attggcaaac
     2101 accggaatca aacaagattc ctcacggatc tattcgaata aaacaccttc aaatttcatt
     2161 cggaaagaaa aagaatccca ttcgaacgaa actaaaatcc cttccgaatg gaaatccaaa
     2221 cgcatccgaa gggaatcaaa gccccatttc ccctcttatc cccaagcaga aaaatggccg
     2281 caaggaacgg ttgtcgaatt aaactcggct gataccaccg cccttaaaat ggttccggga
     2341 attggtagcg tttttgccaa gcggatcatt aaatacaggg acttactagg aggattttat
     2401 tccgtggaac agctaggaga agtatatggt attgacgagg aacgctatga agcgatgaaa
     2461 tcgtggtttt ccgtggaccc gtcagttata agtcatctat ttgtcaacca actgtcagct
     2521 aaagaactgg ccagtcaccc atatgtcagt tataaacaag ctaggatcat tgagaaaatg
     2581 atccggaaaa aagggaaatt acaaggttgg gaggatttat ccctattgga agagtttccg
     2641 gagcatgaac aacaacgatt acgatattat ctttcattcc attgatattt tcactatgtt
     2701 tgtaacaaaa catattctgt atgatctatc tgaagcaagt caaattactg gacccggact
     2761 tggtagccgg caatcccgaa gaactaaaat acccgtataa ggctccggcg gtacgtttca
     2821 cggaatcatt cattttccgc aagccggtta ctttccttgt cggggaaaac ggggcgggaa
     2881 aatctaccct gctggaagcg atgatgagta aatatgagga aagggatgag gaagaaccgg
     2941 gtatgctcta tgacggaacc gaggcctaca agatttacgc caatgtctta cccgagcata
     3001 ttaagctgat cgaaacccga aaaccggaaa agcatttctt cttccgggca gaatcctttt
     3061 ttaaccatgc ggccgaattg gataggcaag cccaactgga attacgtaag tacagcaaga
     3121 tctacgccta taaagcttac ggtggcagga gtttattgga gcaatcgcac ggcgagagct
     3181 ttctcagcgc tttcctgaat tatgccagcc gcaatacatt atttatatta gacgagccgg
     3241 aagccgcact ctccccacaa cggcagctgg cccttttggt gcgtatccat gaactggtga
     3301 ataacggttg ccaactgatt atctccacgc actccccgat cttgatggct tatccgaacg
     3361 cggacattta tgccatcgat gataccggag cgcacatcac cccgtatgag gaaacagagc
     3421 attaccagct cactaaatat ttcctcacgc atacggagca aatgatgaaa gaactgcttg
     3481 ggtgagatta cttctcccaa gcatttacga tctcggcaat gtaaacgata tgcgcattgc
     3541 cgttcttctc atcataccaa cgagggaaaa cgctaggatc taaaaactta gcctcctcga
     3601 tctcggactt atagaccact ttgcattcca acgtaaggcg agcttcctcg aatacaggat
     3661 taccagcctc cgtaaagaac ggtgtcaacc ccgtagcggc cactttatca atctcccggc
     3721 cggatttaga gccacaaatg ctatgggctt tccggtgctc cggtcctagg aaagtaatcg
     3781 tgaactcatt tttagcgtcg ataaactcac gggtataacg ctccggacga ataaaagcaa
     3841 acaccaccgg acggttccat aacactccca cgccgcccca actggcagtc atcatattaa
     3901 acttctcctt atcaccggcg cttaccagca tccactc
//
LOCUS       DBMDTB010000181         3771 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_5597_length_3771_cov_10.873569, whole genome shotgun sequence.
ACCESSION   DBMDTB010000181 DBMDTB010000000
VERSION     DBMDTB010000181.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 3771)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 3771)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3771
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_5597_length_3771_cov_10.873569"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            4..888
                     /locus_tag="ACZPB4_16570"
     CDS             4..888
                     /locus_tag="ACZPB4_16570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-propeller domain-containing protein"
                     /protein_id="HIR1099864.1"
                     /translation="MKIYTFILSACLLLVCSACHEASHYLLLGGSGWDKIAIVNKNTK
                     EIEWEHPLEKGWECNSVAVTPDRNILFSYSKGAKLITRDHEEVWNISAPEGCEMQTAR
                     VLPNGNYLLAWCGYPATIMEVNAKGEILSKTDFDTHIEQPHAQFRQVNKNKRGNYLVP
                     LFATSEIREISPSGQLLKSVKVDGNPFSVAALDNGNYLVACGDAHCFIELNFETGDIV
                     RKVNANDIEGAQLFFVAQLLPKRDGGLYICNWQGHDGEAAKGHYPQLIEINGAGKMVW
                     DLNDNATFGMISSICPID"
     gene            941..2260
                     /locus_tag="ACZPB4_16575"
     CDS             941..2260
                     /locus_tag="ACZPB4_16575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HIR1099865.1"
                     /translation="MEEKNTNATKRRNPVTWVPSVYFAMGLPFVVLNMVTVLMFKGLD
                     ISDAQIALWTSVIMLPWTLKPLWSPFLEMYRTKKFFVVLTQLLSGCLFGLVALALNLP
                     SFFALSIALLGIIALSGATHDVATDGVYMKELSPEDQAKYIGWQGAFYNLAKIVATGG
                     LVYLAGYMMQYFTGIGLEKEAVIYAWMIVMLLCGTIMILLGFYHMKMLPSGGKAATRE
                     HSLKESMAELWLVFKEFFTKKYIVWYICFIILYRFAEGFVIKIVPLFLKAPIADQGLG
                     LTEQEIGLYYGTFGAAAFVLGSLLGGYYISAKGLRKVLFTLCCCFNIPFLVYTFLACF
                     QPDNGLIIASAIVFEYFGYGFGFVGLMLFMMQQVAPGKHQMAHYAFASGIMNLGVMLP
                     GMMSGFVSDWLGYKYFFIVTLLAMIPSFLVAYFVPFTYDDKGNKLVQ"
     gene            2280..3278
                     /locus_tag="ACZPB4_16580"
     CDS             2280..3278
                     /locus_tag="ACZPB4_16580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009291829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 130 protein"
                     /protein_id="HIR1099866.1"
                     /translation="MDNLKIVGAPLPNMPWEDRPEGSKEVVWRYSKNPVIPRDILPTS
                     NSVFNSAVVPFKGGYAGVFRCDDTNRRMRLHVGFSADAIHWSISETKLEFECDDKEIG
                     EFVYAYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTFDFETFHQLENAYLPFNRNGVMF
                     PRKINGNFAMLSRPSDNGHTPFGDIFYSESPDMCFWGKHRHVMSPAAFEDSAWQCTKI
                     GAGPIPIETSEGWLLIYHGVLRSCNGYVYSFGSAILDLEQPWKVKFRSGPYLLSPQKD
                     YECMGDVPNVVFPCAALHDPETKRIAIYYGCADTVTGLAFGYIDEILDFTKKNSII"
     gene            3398..3739
                     /locus_tag="ACZPB4_16585"
     CDS             3398..3739
                     /locus_tag="ACZPB4_16585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099867.1"
                     /translation="MTKIQQFLADLSEEKKSLFVPVFGSMEKFYTVVYLIARNEHVTD
                     QEKPDRYEDRLQVIRQIRNRVEKLVSSYGLDGGEIVADIASDYFEDYVNYKEPELDIT
                     NDEFIAILQKI"
BASE COUNT          929 a          738 c          977 g         1127 t
ORIGIN      
        1 accatgaaaa tctatacttt tatattatcc gcatgcctgc tactcgtatg ttccgcatgt
       61 catgaggcgt cgcattatct tttattaggc ggttccggct gggacaaaat cgccatcgta
      121 aacaagaaca cgaaagaaat tgaatgggag catcccttgg aaaaaggatg ggaatgtaat
      181 tccgtagctg ttactcccga ccggaatatc cttttttcct attcgaaagg ggcgaagcta
      241 atcacccggg atcatgagga ggtctggaat atctccgctc cggaaggctg tgagatgcag
      301 acggcccgtg tacttcccaa cggtaattat ttattagcgt ggtgtggata cccggcgacg
      361 atcatggagg tgaatgcaaa aggagagatc ctgtcgaaaa cggatttcga cacccatatc
      421 gagcaacccc atgcccaatt ccgtcaagta aacaagaata agcggggcaa ttatctagtg
      481 cccttgttcg ctacctccga gatccgggaa atatccccgt ccggtcaatt gctgaaaagc
      541 gtgaaagtag acggtaaccc gtttagcgtg gctgcgttgg ataacggtaa ttatctggtc
      601 gcttgcggtg atgcccattg cttcatagag ctgaatttcg agaccggaga tatcgttcgc
      661 aaggtgaatg cgaacgatat cgagggagcc cagcttttct ttgttgccca gttgctccct
      721 aaacgggacg gtggtttgta tatctgtaac tggcaaggcc atgacggaga ggctgcgaaa
      781 ggacattacc cgcagttgat cgagataaac ggagccggaa agatggtctg ggatttgaat
      841 gataacgcta ccttcgggat gatctcctct atttgtccga tcgattaaag atatatccgg
      901 attattaatt atatttgtac acctaaattc taaataaagc atggaagaga aaaacacgaa
      961 tgctactaaa cgtcgaaacc ctgtgacttg ggtccctagt gtctattttg ctatgggatt
     1021 gccttttgta gtgctgaaca tggttaccgt actcatgttt aagggattgg atatctcgga
     1081 tgcccagatt gcgttatgga cctcggttat catgttacct tggaccttaa agcctttatg
     1141 gagcccgttt ttggaaatgt atcgtactaa gaaattcttt gtcgtattga cccagttgtt
     1201 atccggttgc ttattcggtt tagtggcctt ggcgttaaac ttgccgagtt tctttgctct
     1261 atctatcgca ttattaggta ttatagcgct tagcggggct acgcatgacg tggcaacgga
     1321 tggcgtttat atgaaagagc tctcgccgga ggatcaagcc aaatatatcg gttggcaagg
     1381 tgcgttttac aatttggcga agatcgtagc cacgggtggt ctggtttatc tggcgggtta
     1441 tatgatgcaa tattttaccg ggataggatt ggagaaagag gccgtgatat acgcttggat
     1501 gatcgttatg ctgctttgcg gtacgatcat gatcctgctt ggtttttatc atatgaagat
     1561 gttgccttcg ggtgggaaag ccgctaccag agaacattcg ttgaaggaaa gtatggctga
     1621 gttatggctg gtcttcaagg agttcttcac gaagaagtat atcgtgtggt atatctgttt
     1681 catcatattg tatcgttttg ccgagggttt cgtgataaag atcgtacctt tgttcttgaa
     1741 agctccgata gctgatcaag gattaggact aacggagcaa gaaattggtt tgtattatgg
     1801 tacgtttggg gcggcggcgt tcgtgctggg ttctttgctt ggtggatatt atatctcggc
     1861 caagggattg cgaaaggtat tgtttacgct ttgttgttgt ttcaatatac cgtttttggt
     1921 atacacgttc ttggcgtgtt tccagcctga taatggtctc attatcgctt ccgccatcgt
     1981 attcgagtat tttggctatg gattcggttt cgtgggcttg atgctgttta tgatgcaaca
     2041 ggtagctccg ggcaagcatc agatggcgca ttatgcgttc gcttcaggta tcatgaacct
     2101 tggcgtaatg cttccgggaa tgatgagcgg tttcgtgagc gactggctag gttataagta
     2161 tttctttatc gtgaccttgc tggcgatgat cccttcattc ttggtagcct atttcgtacc
     2221 gttcacgtat gacgataaag gtaataagtt agtacagtaa tattttaata ggattagtta
     2281 tggataattt gaaaatcgta ggcgctccgc tgcctaatat gccttgggaa gatcgtcccg
     2341 agggtagcaa agaagtagtg tggagatatt cgaagaaccc ggtgattcct cgtgatatcc
     2401 ttccgacatc gaacagcgtg ttcaacagtg ctgttgtccc tttcaaaggt ggttatgccg
     2461 gtgtgttccg ttgcgacgat acgaatcgcc ggatgcgttt gcacgtaggt tttagcgcag
     2521 atgccattca ttggagtatc tccgagacaa aactcgagtt tgagtgcgac gacaaggaga
     2581 tcggcgagtt tgtttacgcc tacgaccccc gtgtatgttt tatcgaggat cgttattatg
     2641 tgacttggtg taacggttat catggcccga cgatcggcgt ggcttacacg ttcgatttcg
     2701 agaccttcca tcagctggag aacgcttatc tgcctttcaa ccgtaatggc gtgatgttcc
     2761 ctcgtaagat taacggaaac ttcgccatgt taagccgtcc gagcgacaac ggtcatactc
     2821 cgttcggcga tatattctat agcgagtctc cggatatgtg tttctggggt aaacatcgcc
     2881 acgtgatgtc tccggctgcg ttcgaggata gcgcttggca gtgtacgaag atcggtgcgg
     2941 gccctatccc tatcgagact tccgagggct ggttattgat ttaccacggc gtgcttcgtt
     3001 cttgcaacgg gtatgtgtat agcttcggtt ccgctatctt ggatttggag caaccttgga
     3061 aagtgaaatt ccgttctgga ccttatttgt tatccccgca aaaggattac gagtgcatgg
     3121 gagacgttcc gaacgtagtc tttccttgtg ccgccttgca tgatccggag acgaaacgta
     3181 tcgctatcta ttacggctgc gcagatacgg taacaggatt ggcttttggc tatattgatg
     3241 agattttgga ttttacgaag aagaattcaa tcatttaaaa gactcgagaa gaacaatata
     3301 cttttgttgt cgaaacaata tacttttaca cacgaaagta tattgtttta gaacaaaaag
     3361 tatattgttt tttttattag gtaaaagagt aagagttatg acaaagatac aacagttttt
     3421 ggcagatctg tccgaggaga agaaatcctt gtttgtccct gttttcggga gcatggagaa
     3481 attttatacg gtagtttact tgatcgcccg gaatgagcac gtcactgatc aggagaagcc
     3541 agatcgttat gaggatcgtt tacaggtgat tcgccagata cgtaaccggg tggagaaact
     3601 agtttcctcg tatggcttgg acggagggga gatcgtagcc gatatcgcca gcgactattt
     3661 tgaggattat gtcaattaca aagagccgga gctagacatt acgaatgatg agtttatcgc
     3721 tatcctccag aaaatatagg agataaatat aattttattg tgtggtagta t
//
LOCUS       DBMDTB010000182         3690 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_5752_length_3690_cov_10.077180, whole genome shotgun sequence.
ACCESSION   DBMDTB010000182 DBMDTB010000000
VERSION     DBMDTB010000182.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 3690)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 3690)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3690
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_5752_length_3690_cov_10.077180"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(174..2486)
                     /gene="bglX"
                     /locus_tag="ACZPB4_16590"
     CDS             complement(174..2486)
                     /gene="bglX"
                     /locus_tag="ACZPB4_16590"
                     /EC_number="3.2.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011965980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucosidase BglX"
                     /protein_id="HIR1099868.1"
                     /translation="MKFLKSSVLFISMACIVPVCSIAREKSERITRAEIEQKSADEFI
                     NGLMSRMTVDEKIGQLNLPSYGNVMPNPKKSEIASRIVRGEVGGIFNIFGVDAIRQLQ
                     EVAVKESRLGIPIIVGADICNGYKTVFPIPLGLSCSWKPENIEEVARISAKEVGADGI
                     CWTYSPMVDISHDARWGRVKEGAGEDPFLGGIMAQAWVRGYQGNDLSADTTLMACVKH
                     YALYGAAEAGRDYNTVDMSRVTAMNYYMRPYQAAVEAGVGSIMTSFNEFESIPATGNT
                     WLLNDVLRKQWGFNGFVVSDFTAIAEMVNHGIGNSQEVGVKALKAGVDMDMIADCYHA
                     VLKKSLEEGKITEAEIDSACRRILISKYQLGLFHDPYKYCNPKRAAKEFLSVNNVSAA
                     RRIAAESFVLLKNDNNLLPLKGCRKVAVVGPLADSKANMAGSWKYDEQTKSYHGLVED
                     LQESLGNGVEVVFAKGSNLVDDSVYEANFTDQNRSTRDDRSDEQLIAEALKVAEGADV
                     IIAALGESIDMSGEGASRAILEMPQTQKKLLDAIQKTGKPIVMVLFTGRPLALQSEEK
                     QVNAILNVWFGGTEAGAAIADVLTGKVSPTGKLTMSFPRVTGQCPIYYNHKMTGRPMS
                     PDAWYTRYVSNYIDVLNEPLYPFGYGLSYTTYTYGDVSLNTNSMDANGKIQASVIVTN
                     TGAQDGEEIVQLYLRDIVRSITPPVQELKGFKRVALKAGESKKVTFDIDVDMLKFYDS
                     TLDYVAEPGEFQVMIGGNSKEVKTASFTLK"
     gene            complement(2693..3574)
                     /locus_tag="ACZPB4_16595"
     CDS             complement(2693..3574)
                     /locus_tag="ACZPB4_16595"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HIR1099869.1"
                     /translation="MVKKWIFPLLIGVCLINTSMAQENPILLFPKGAPGETIKLIEKA
                     DTDGGKTGGESVLRITNVSEPTITIYHAPDEVASGAAMIVCPGGGYNILAYDLEGDEV
                     CEWLNNLGITAVLLKYRVPRREGLEKHEAPLQDVQRAIGYVRANAENLNIDPKRIGVM
                     GFSAGGHLAAMVSNNFLKRTYPAIDATDKVSCRPDYCLLVYPAYLDGENFQLAPELKV
                     SSATPPTMLIQAEDDKSYINSSIFYYYALKEAGVPAWMHLYSQGGHGYGLRDTGASVN
                     EWPDRAEDWFREIGLIE"
BASE COUNT         1082 a          950 c          592 g         1066 t
ORIGIN      
        1 ttgttcgttg tctgagattt aagtgcaagc caaccacgca ctacatgctt acaaaccact
       61 tctacccgct gtcaaaaccg gtcatcccca tggttttgta atatttcttt tggcaaagat
      121 acatataatt tcgaatttag caaagcccca taactgattc cttacgatta ggattatttt
      181 aatgtaaacg aagctgtttt cacctcttta ctatttccac cgatcattac ctgaaactca
      241 cccggctcag cgacataatc taaggttgaa tcgtagaatt tcaacatatc cacatcaata
      301 tcaaaggtta ctttcttgct ttctcccgct tttaacgcaa ctcgcttgaa tcctttcaat
      361 tcttggaccg gaggggttat gctgcgtacg atatcacgta aataaagctg tacgatttcc
      421 tctccatcct gagccccggt attggtaaca atcacggatg cttgaatttt tccatttgca
      481 tccatagaat tcgtattcaa agatacatcg ccatacgtat aagtcgtata actcaaaccg
      541 taaccaaatg gataaagagg ctcattcaac acatctatat aattggagac ataacgagtg
      601 taccaagcat cgggagacat aggacgtcct gtcatcttat gattgtaata gatcggacat
      661 tggcctgtta cacgaggaaa agacatggtt aacttccccg tcggagaaac ctttccggtc
      721 aagacatcgg caatagccgc tcctgcttcc gtaccaccga accatacgtt caagatcgca
      781 ttcacctgct tttcctcgga ttgtaatgcc aaaggtcttc cggtaaaaag taccattacg
      841 atcggctttc ctgtcttttg gatagcatcc agtaattttt tctgcgtttg cggcatttca
      901 aggatggctc tactagcgcc ttctccactc atatctatcg attcacccaa agcagcgata
      961 atcacatcag cgccttccgc cacttttagg gcctcggcga ttaattgttc atcgcttcta
     1021 tcatcccggg ttgaacgatt ttgatccgta aagtttgctt catagacgga atcatcgact
     1081 agattgctgc cttttgcaaa aacaacctct actccatttc ccaaagattc ctgtaaatcc
     1141 tctaccaatc catgataaga tttagtctgc tcatcatatt tccacgatcc agccatattc
     1201 gccttgctat ccgctaaagg accgaccaca gcgaccttac gacatccttt aagtggaagc
     1261 agattattat catttttaag taacacgaaa gactccgccg caatacgacg ggccgcggat
     1321 acgttattta ccgacaagaa ctctttggcg gctcttttcg gattacaata tttatatgga
     1381 tcatggaaca atcccaattg gtattttgag attagtattc tccggcaagc agagtcaatc
     1441 tcagcctctg ttattttccc ttcttccaat gatttcttta atacggcatg ataacagtcc
     1501 gctatcatat ccatatcgac acccgccttt agcgccttga ctccgacttc ctgactatta
     1561 cctattccat ggtttaccat ctccgctatt gccgtaaaat cagacacgac aaagccgtta
     1621 aatccccatt gtttacgcaa cacgtcatta agaagccaag tatttccggt tgcggggata
     1681 ctttcaaatt cgttgaatga agtcatgata cttcctactc ctgcttctac agcagcctga
     1741 taaggacgca tgtaataatt catggcagtc acacggctca tatctaccgt attataatcc
     1801 cgaccagcct cggccgctcc ataaagcgca taatgcttta cacatgccat aagagtcgta
     1861 tcagccgata aatcattgcc ttgataacca cgcacccatg cttgagccat tatacctcca
     1921 agaaacggat cctcgcccgc tccttccttt acccgtcccc accgggcatc atgagatata
     1981 tcgaccatcg ggctatatgt ccaacagata ccatcagcac caacttcctt tgcggaaatt
     2041 cgagcgacct cttctatatt ctccggtttc caactacacg aaagacctag aggaatggga
     2101 aaaacagttt tataaccatt acaaatatca gcgccaacaa ttataggaat ccccaaccga
     2161 ctttctttaa ccgcgacttc ttgtaactgc cggatcgcat cgacaccgaa tatattaaat
     2221 ataccaccaa cctctcctcg tacaatacga ctggctatct cactcttttt aggatttggc
     2281 attacgtttc cataactagg aagattcaat tggccaattt tctcatcaac ggtcattcga
     2341 ctcatcagac catttataaa ttcatccgca cttttctgtt caatctcagc tcttgtgatt
     2401 ctctcacttt tttctctcgc tatcgaacaa acaggcacta tacatgccat tgaaataaat
     2461 aaaactgaac ttttaaggaa tttcataact tagctttttt acttcaaaaa aagcccgaat
     2521 aacagaaaac agcaataaac tcactacttc aaagatacga tatgctatag aacacgcttt
     2581 cctagactac gcttttacta cgtttaccat caataataaa ctagtaataa ataaattgcg
     2641 caatcgattt tagaatctac tccgcaagtc tccagaaaag atatctggag ttctattcga
     2701 ttagaccgat ctcacgaaac caatcttcag cccgatccgg ccattcattt acagacgctc
     2761 ccgtatctcg taacccgtat ccatggccac cttgactata taaatgcatc catgccggaa
     2821 caccagcttc ctttaaggca taataataga aaatactact gttaatataa gatttatcat
     2881 cttccgcttg aattaacatg gttggaggtg tggcagatga aacctttaac tctggtgcca
     2941 attggaagtt ctctccatct aaataagcag gataaaccaa taaacaataa tccggacgac
     3001 aacttacttt atccgtagca tcaatagccg gataagtacg tttcaaaaaa ttattgctaa
     3061 ccatggcagc caaatggcca ccagccgaga atcccatcac accgatccgc tttggatcta
     3121 tattcaagtt ctcagcgttc gctcgaacat aaccaatcgc acgctgtaca tcttgcaaag
     3181 gagcttcgtg tttttccagt ccttctcgtc ttggaacccg gtatttaagt aagaccgcag
     3241 ttattccaag attattaagc cattcacaga cttcatcacc ttccaaatca taagctaaaa
     3301 tattgtaacc accaccggga cagacaatca tagcggcacc cgaggccact tcatccggag
     3361 catgatatat agtaatcgtt ggctcactta cattcgtaat acgcaaaaca ctctcaccac
     3421 cggtttttcc accgtccgta tcagctttct ctattaattt aatagtttct cccggcgccc
     3481 cttttgggaa taataaaatc ggattttctt gtgccataga cgtattgatt aaacaaaccc
     3541 caatcaataa agggaatatc cacttcttaa ccatacaaca cattattaag ttatagggag
     3601 cgaatatata catcttattt tatttatcca atcagaatcg aataaataaa aacagaaaaa
     3661 ggagtcaccc cttacggact gactcctctc
//
LOCUS       DBMDTB010000183         3646 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_5839_length_3646_cov_7.479549, whole genome shotgun sequence.
ACCESSION   DBMDTB010000183 DBMDTB010000000
VERSION     DBMDTB010000183.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 3646)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 3646)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3646
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_5839_length_3646_cov_7.479549"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(51..860)
                     /locus_tag="ACZPB4_16600"
     CDS             complement(51..860)
                     /locus_tag="ACZPB4_16600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6261 family protein"
                     /protein_id="HIR1099870.1"
                     /translation="MGKITKVKDINIAKLNNAEYRTFMARYGSLIAGDGGDSESPDEI
                     SFDPNDPLGIPAELRTAFDSDFKLLTDAVNQSSASEETAQMSAIDKERDDLLTFITST
                     VSQMMKSPLAAQRTAAEKLYLAVKPYIGAARLANLQETAAIEGLLTDLAKEGMPEALA
                     AITLTEVVAALKEKNQQYAALTEQRTNARADLPVESAKKIRLRMDEEYDEMTTYAFAQ
                     SVVKPTQVTATFISRLNALIDETNALYNQRIALVKAAAAKKQADSESPSEI"
     gene            complement(1201..1875)
                     /locus_tag="ACZPB4_16605"
     CDS             complement(1201..1875)
                     /locus_tag="ACZPB4_16605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099871.1"
                     /translation="MRNIFLLYCVALAGLCACESEEKVYPDGPGLNEVGMQIVLTDPE
                     LNDLLNPESPSFLGEEYTKGILVMYLNAGKKTLCQFVPQYTNEGGTQKEWNMIYPPYE
                     DYERDGRVKKNTKGYYYLPFPFNKTEENQDVSYIYVQYPNGSEDEIKSQMYIADGIFL
                     IDQIWVNGELAYSMSPREGSLSTKQYYNPEYYPFLVPTLDDNGKQIGDLVQPEGGTRI
                     IVIKKK"
     gene            complement(1898..3229)
                     /locus_tag="ACZPB4_16610"
     CDS             complement(1898..3229)
                     /locus_tag="ACZPB4_16610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C10 family peptidase"
                     /protein_id="HIR1099872.1"
                     /translation="MKATNTLLSTIIIGVTLIIMTGCSQGEDLIDAGTQALNAATNND
                     KELVLTASEQIALSVKQKGSYDISEKEAKKNFESYAKTIHKEKAVKVKALSLKKNKKN
                     GRNLYYEVIFENDKGTGFSLLSADERVDKLLCYSENGSISDTSFNKSLKYCLELVDLY
                     VEEQTQKELDIESLASSANQKIKTANKGKAITKALPPFDPDDPNSPWSYDRTDVKNEV
                     TERIKQVHAGWHQESPFNDLLPLLPPDYTQRAYTGCAMVAVSQIMAYHQKPYSNYITA
                     AMWPTMIANLDTSVELKRLMLDLFNTMNTGYDATGTSSNISKARDFLNNNGYTAGSAQ
                     DYTFDRAWRALSYGPTYIRGTRASGDGHAWIIDGVRNTRTTSTDIYTITYNGRVFEAS
                     GSSSITSFQTVRYDWGGGNENDNTWFNSGIFTPSSNTSPYDRNVRMISYVY"
BASE COUNT          754 a          848 c          962 g         1082 t
ORIGIN      
        1 aggggagccc catcattctt aaatctaaaa aacatgaggg cctcacggct ttatatctct
       61 gacggcgatt cgctatccgc ttgcttcttg gcggcggcgg ctttcacgag cgctatgcgt
      121 tggttgtaga gggcgttggt ctcgtcgatc agcgcgttga ggcggctgat gaaggtggcc
      181 gtcacctgag tgggcttcac cacgctttgg gcgaaggcgt aggtggtcat ctcgtcgtat
      241 tcctcgtcca tgcggaggcg gattttcttg gcgctctcca ccgggaggtc ggcccgtgcg
      301 ttggtgcgct gctcggtcaa ggctgcgtat tgctggttct tctccttcag cgcggccact
      361 acctcggtga gggtgatcgc cgccagtgcc tcgggcatgc cctccttggc taggtcggtc
      421 agcaagccct cgatggcggc cgtctcctgc aagttggcga ggcgtgcggc gccgatgtag
      481 ggtttcacgg cgaggtatag cttctcggcg gccgtgcgtt gcgccgccag cgggcttttc
      541 atcatttgcg atacggtgga ggtgatgaag gtgagcaggt cgtctcgctc cttgtcgatg
      601 gcggacatct gcgcggtttc ctcgctggcg gaggattggt tgacggcgtc ggtcagcagc
      661 ttgaagtcgc tgtcgaaggc cgtgcgcagc tcggcgggga tgcccagcgg gtcgttcggg
      721 tcgaagctga tctcgtcggg agattcggaa tcgccgccgt cacctgcgat caggctcccg
      781 tagcgggcca tgaaggtccg gtactcggcg ttgtttaatt ttgcgatgtt aatgtctttt
      841 acttttgtaa tctttcccat tttcttattg atttagatcc atgatctgtt taacactggc
      901 taaaggtacg acaaatcgat tgatatagct ctgggaaccg ccgtgttttt cgcggattcg
      961 acctcgcggc aggtgaaaag tcgaatcttg cgaaaatacg gggcttacat cgggtgcgaa
     1021 acggaatctt agggaaatat tccaccttgc ggcaggtgcg tggtggaatt cgcgaaaaat
     1081 gcggggggta catcgggcgc gaggccgaat cttggagaaa tgcggtatcc cgcggcaggt
     1141 gcgcggtgga atctttagaa aatgcgaggc ccaaccttgg tggccgggcc tcgcgataaa
     1201 tcatttcttc ttgatcacga tgatacgcgt gccgccctcg ggctgtacca gatccccgat
     1261 ctgcttgcca ttgtcatcta acgtaggaac caagaacgga taatattccg ggttgtaata
     1321 ctgctttgtg cttagggagc cttctcgggg agacatggaa taggcgagct cgccgttgac
     1381 ccatatctgg tctataagga atatgccgtc ggcgatgtac atttgtgatt ttatctcatc
     1441 ctcgcttccg tttgggtact gaacgtatat ataggagaca tcctgattct cttctgtttt
     1501 gttaaaaggg aacgggaggt aatagtatcc tttcgtgttc ttttttaccc ttccgtctct
     1561 ttcatagtcc tcgtagggtg gatagatcat gttccactct ttctgtgtac ctccctcgtt
     1621 cgtgtattga ggcacgaatt ggcagagggt ctttttgccc gcgttaaggt acatgacgag
     1681 gatgcctttc gtatattctt ctccaaggaa gctgggggat tccgggttca agagatcgtt
     1741 cagctccggg tctgtcagca cgatctgcat gcctacctcg ttaagaccgg gcccgtctgg
     1801 atatactttt tcttccgatt cgcaagcgca gaggccggct agcgctacgc agtataaaag
     1861 gaatatattt ctcataggat ttgaagtttt aaattgatta ataaacatag ctaatcatcc
     1921 gtacatttcg atcgtatggg cttgtgttag atgatggcgt aaaaataccg ctgttaaacc
     1981 aagtgttatc gttttcatta ccccctcccc aatcataccg tacggtctga aaggaggtga
     2041 tggaagaact accggaggct tcaaacactc tcccgttata tgtaatggta taaatatcgg
     2101 tactggtggt tctcgtgttc cgtactccgt caataatcca agcatgaccg tcaccgctag
     2161 ctcttgttcc tcttatatat gtagggccat agcttaacgc tctccaagcc ctgtcaaatg
     2221 tataatcttg agcggatccg gcggtatagc cgttattgtt taggaagtct ctggctttgg
     2281 atatattgct acttgtcccg gtcgcatcat atcctgtgtt catcgtatta aacaaatcaa
     2341 gcataaggcg ctttagctct acggaggtgt ctaaattcgc gatcatcgta ggccacatcg
     2401 ccgccgtgat ataattgctg tagggctttt ggtgatatgc catgatttgc gagacggcta
     2461 ccatagcaca acccgtatag gctctttgcg tataatcggg aggaagcaat ggtaataaat
     2521 cgttgaatgg actttcctga tgccatcctg cgtgaacttg cttgatcctt tcggtgactt
     2581 cgttttttac gtctgtccgg tcataactcc aagggctgtt cgggtcgtcg gggtcaaaag
     2641 gtgggagcgc tttggtgatt gccttgcctt tatttgccgt ttttatcttt tgattcgccg
     2701 aagaggccag actttctatg tctaattcct tttgggtttg ctcctccaca tacaaatcga
     2761 ctagctctag gcagtatttc aagctcttgt taaacgaggt gtccgatata gacccgtttt
     2821 ctgagtaaca aagtagcttg tctacacgtt catctgccga taatagggag aatcccgttc
     2881 ctttgtcgtt ttcgaatata acttcgtagt ataggtttct cccgtttttc ttgttcttct
     2941 tcaatgagag ggcttttact tttacggctt tctccttgtg gatggtctta gcgtagctct
     3001 cgaagttctt tttcgcttct ttttccgaga tatcgtatga acctttctgt tttacggaaa
     3061 gggcgatttg ctcggaggcg gttaagacca actccttgtc attgtttgtc gccgcgttta
     3121 acgcttgggt gccagcatct ataagatctt caccttgtga acatcccgtc atgattatta
     3181 aagtaacgcc gataataatc gtactcagta aagtattcgt tgctttcata tgagattgga
     3241 tttagagatt agcatgagaa aagagtgatt atcaaccttt gttgatcttg agaaggaact
     3301 ccgaagagac gggaccattt attctttgaa tagaataggt aaatgttgag tcataaaggt
     3361 ctggattaaa tcggacaaaa acaaattctg taatcagaat cttgtatgaa atctcgttat
     3421 tattcatttg tcgcggccct cttgaaacaa caaaggcctt gccggggtag caaggcccat
     3481 cgcgagggat gagatgcggc tcgccgcgtc tctacaacgc ctccttgttc cacttgttca
     3541 gcggattctt cccctcggga gtatagagct gggcgatacg ggcggcgtag gctttctcta
     3601 ccttgccccg gacgatcttc atggtgctgt ttaccatgcc gttttg
//
LOCUS       DBMDTB010000184         3639 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_5847_length_3639_cov_13.313454, whole genome shotgun sequence.
ACCESSION   DBMDTB010000184 DBMDTB010000000
VERSION     DBMDTB010000184.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 3639)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 3639)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3639
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_5847_length_3639_cov_13.313454"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..1382)
                     /locus_tag="ACZPB4_16615"
     CDS             complement(<1..1382)
                     /locus_tag="ACZPB4_16615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ChbG/HpnK family deacetylase"
                     /protein_id="HIR1099873.1"
                     /translation="MKISNVKRILCGCLLFAATWPAFSQPATNPRLIIRADDMGSFRS
                     ANIACMEGYKNGVETCIEVMVVTSWFPEAARLLRENPGIDVGLHLTFTSEWDNVKWRP
                     LTHCPSLTDSNGYFLPMMSPNSAYPGLAILENTWSLAEIEQEARAQIEMALKNIPQIS
                     HISGHMGSTGFDPEVVKLMRRLSEEYHLPVVDRVEAMQEYDFTYSGYDGASKTPAEKE
                     ASFIRMLDKLEPGKRYMFLDHPALDNEEMKTVGHIGYENVAMDRQGVTDLFTSPKVKQ
                     ALKDKNIDLISYNDLTKELPRAEASKALDKAFGNYLRAVKKADQDLHSIMILQHGKVV
                     KEQWLGEGDRHTPHVLNSVSKTFTATAIGFAVAEGKLKVTDKVISFFPDQLPAEVSPY
                     LKELEIRHLLTMSSGHDVDPTALVRQKGNEKADWAKLFLSAPLVHKPGTYFVYNSLGT
                     YMLSAIIQKVT"
     gene            complement(1410..1823)
                     /locus_tag="ACZPB4_16620"
     CDS             complement(1410..1823)
                     /locus_tag="ACZPB4_16620"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0047617 - fatty acyl-CoA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HIR1099874.1"
                     /translation="MDERIKEKLINRAKTNPYVNFLGIDFTVIEEGRVEAHMPLHDEQ
                     RQYNGVTHGGVLAALADTIAGFAAYTMTPLEKDVLTAELKMSFLRAAWGNELIAKGAV
                     IKAGRNIHFCECEIYCDDKLVSKSSGTFCVVHPQV"
     gene            complement(1834..2400)
                     /gene="xpt"
                     /locus_tag="ACZPB4_16625"
     CDS             complement(1834..2400)
                     /gene="xpt"
                     /locus_tag="ACZPB4_16625"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000310 - xanthine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0043101 - purine-containing compound
                     salvage [Evidence IEA];
                     GO_process: GO:0046110 - xanthine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HIR1099875.1"
                     /translation="MELLKQRILQDGRCYPGGILKVDSFINHQMDPMLMYKIAEEFIR
                     RFQDRKINKIVTIEASGIAPAIMVGYIMQLPVVFVKKKKPKTMENMLSTVVHSFTKDR
                     DYTVCISNNFLTPEDHILFIDDFLAYGNAAMGMVELAEQSGAVIEGMGFIIEKAFQDG
                     GNLLREKGIRVESLAIIDNLDDCKITVR"
     gene            complement(2407..>3639)
                     /locus_tag="ACZPB4_16630"
     CDS             complement(2407..>3639)
                     /locus_tag="ACZPB4_16630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008769858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015851 - nucleobase transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="HIR1099876.1"
                     /translation="AIITPPLIIAGALKLDLETTGFLVSMALFASGVSTFVQCRKLGP
                     VGAGLLCIQGTSFSFIGPIITAGLAGGLPLIFGVCIAASPVEMIVSRTFKYLRSVITP
                     LVSGIVVLLIGLSLIKVGVVACGGGYTAMDNGTFGSLRNIGVAVCVLLSVLFFNRCKN
                     KYLRMSSIVLGLCIGYAIAFAMGMVDMEAVSSQNLRGFNIPVPFKYGLDFNISSFVAI
                     ALIYLITAIEATGDITANSMISGKSIEGEGYLRRVSGGVLADGVNSFISGIFNSFPNS
                     IFAQNNGIIQLTGVASRYVGYYIAGMLILLGLFPVVGVIFSLMPDPVLGGATLLMFGT
                     VAAAGIRIIAAQDINRKATLVLAVSLSLGLGVELMPDILGAAPQVIRGIFSSGITTGG
                     LTAILANLFIRVKEDQTE"
BASE COUNT          929 a         1061 c          822 g          827 t
ORIGIN      
        1 gtcaccttct ggatgatagc ggaaagcata tacgtgccga ggctgttgta tacgaaatag
       61 gttcccggtt tatgtaccaa cggcgccgag aggaagagct ttgcccaatc ggccttctcg
      121 ttccccttct gccgtactaa agcggtggga tcgacatcat ggccggagga catggtcaat
      181 aggtgacgta tctccagctc tttcaagtaa gggcttacct cggccggtaa ttggtcgggg
      241 aagaaggaga tcaccttgtc cgtgaccttc aatttaccct ccgcgacggc gaaaccgata
      301 gccgtagccg taaaggtctt gctaacggag ttcaagacgt gcggcgtatg gcggtcgccc
      361 tcacccagcc attgctcctt tacgaccttt ccatgctgga ggatcatgat actatgtaag
      421 tcttgatccg cctttttcac cgcccgcaga taattgccga acgccttatc caaggctttc
      481 gaggcttccg cacgagggag ttccttggtc aggtcgttat aactgatcag gtctatgttc
      541 ttatccttca aggcttgctt caccttcgga ctggtaaaaa gatcggtcac gccttgacgg
      601 tccatcgcca cgttctcgta gccgatatgc ccgacggttt tcatctcctc gttatccaag
      661 gccgggtgat ccaagaacat atagcgttta ccgggttcca gcttatccaa catccggatg
      721 aaactggcct ccttctcggc cggggtcttg gaggctccat catacccgga ataggtgaaa
      781 tcgtattcct gcatcgcctc tacccgatcc acgaccggca gatgatattc ctcggacaag
      841 cgacgcatca gcttcaccac ctccggatcg aaaccggtcg atcccatatg gccggagata
      901 tggctgatct ggggaatgtt cttcaaggcc atctctatct gggcccgagc ctcctgctcg
      961 atctcggcca agctccatgt attctccaga atggccagac ccgggtaggc ggaattcgga
     1021 gacatcatcg gcaagaaata gccattgcta tcggtcaagc tgggacaatg cgtcagcgga
     1081 cgccatttca cgttatccca ttcgctggta aacgtcaggt gaagcccgac atctatcccc
     1141 gggttctccc tcaacagccg ggcggcctcg gggaaccacg aggtgacaac cataacctct
     1201 atacaggtct ccaccccatt cttataccct tccatacacg ctatattggc ggaacggaac
     1261 gaccccatgt catccgcacg gatgatcagg cggggattcg tggcaggctg gctgaatgcc
     1321 ggccacgtag cggcgaacaa caggcagccg caaaggattc tttttacatt tgaaatcttc
     1381 atgatattga taaataagta acatcttttc tatacttggg gatggaccac acagaaggtg
     1441 ccggaagatt tgctcaccaa cttatcgtcg caataaatct cgcactcaca aaaatgtata
     1501 ttccgtcccg ccttgatcac ggcacccttg gcgatcagct cattgcccca agcggcccgt
     1561 aagaaagaca ttttcaattc tgccgtcagc acgtctttct ccagcggagt catcgtatag
     1621 gcggcgaaac cggcgatcgt atccgccaaa gcagccaaga cacccccatg cgtcacgccg
     1681 ttatattgtc tctgctcgtc atgcaagggc atatgtgcct ctacacgacc ttcctcgata
     1741 accgtgaagt cgatccccag aaaattcaca taaggattcg tcttcgcacg gttaatcaac
     1801 ttttctttta ttctctcatc catatctttt cctttaacga accgttatct tacaatcatc
     1861 cagattatcg ataatggcga ggctctccac acgtatgccc ttttcacgta gcaggttccc
     1921 gccatcttga aacgccttct cgataataaa acccataccc tcgatcacgg ctcccgattg
     1981 ctccgccaac tcgaccattc ccatggcggc gtttccgtaa gccaagaaat catcgataaa
     2041 caggatatga tcctccggag tcaagaagtt attgctgata cataccgtat agtcacgatc
     2101 cttcgtgaag gaatggacca cggtagagag catgttctcc atcgtcttcg gtttcttctt
     2161 ctttacgaag accaccggca gctgcatgat ataacccacc ataatggccg gggcgatgcc
     2221 gctcgcctcg atggtcacga tcttgtttat cttacgatct tgaaagcgac ggataaattc
     2281 ctcggcgatc ttatacatca acatcggatc catttgatga ttgataaaac tatccacttt
     2341 aaggataccg ccgggataac agcggccgtc ttgcaagatg cgttgcttca ataattccat
     2401 aatttgttat tctgtttgat cttcttttac acgtataaat aaattcgcca gaatggccgt
     2461 caagccaccc gtcgttatgc cggaggaaaa aatgccacgg atcacttgag gagcggcccc
     2521 tagaatatcc ggcatcagtt ccacccccaa ccccaaggac aaactaaccg ccaacaccaa
     2581 cgtggccttc cggttgatat cttgggcggc gataatacgg atacctgccg ccgccaccgt
     2641 accgaacatc agcagggtag cccctcccag caccggatcg ggcatcaagg agaagataac
     2701 gccgacaacc gggaataacc ccaacaggat cagcataccc gctatataat accccacgta
     2761 ccggctggcg actcccgtca gctggatgat cccgttattc tgggcgaaga tagagttcgg
     2821 gaaagagttg aaaattccgg agataaacga gttcacccca tccgccagca ccccgccgga
     2881 gactcgcctc aggtagcctt ctccctcgat cgatttcccc gatatcatcg agttggccgt
     2941 aatatccccc gtagcctcga tcgccgtgat cagatagatc aaggcgatcg ccacaaatga
     3001 agatatatta aaatccaatc catatttgaa gggaaccggg atattaaacc ctctcaggtt
     3061 ttgcgaggag acagcctcca tatccaccat ccccatggcg aaagcgatcg cgtaaccgat
     3121 acacaaccct agcacgatgg aactcatccg caagtacttg ttcttacaac gattgaagaa
     3181 caagacactc aacaagacgc acacagctac cccgatatta cgcaaactac cgaacgtacc
     3241 gttatccata gccgtatacc ccccaccgca agcgaccact ccaaccttga tcaagctcaa
     3301 gccgatgagc aacaccacga tacccgatac caagggagta atcaccgagc gcagatactt
     3361 aaaagtacgg ctcacgatca tctctaccgg agaggcggcg atacaaacgc cgaaaataag
     3421 gggaagccct cccgccaaac cagccgtgat aatcgggccg ataaacgaga agctggtccc
     3481 ttggatacat agcagccccg ccccgaccgg tcctaattta cgacattgaa cgaatgtgga
     3541 taccccggag gcaaacagag ccatggaaac caagaaaccg gtcgtctcca gatccagttt
     3601 cagcgccccg gcgataatca agggaggtgt tatgatcgc
//
LOCUS       DBMDTB010000185         3615 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_5892_length_3615_cov_12.994593, whole genome shotgun sequence.
ACCESSION   DBMDTB010000185 DBMDTB010000000
VERSION     DBMDTB010000185.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 3615)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 3615)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3615
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_5892_length_3615_cov_12.994593"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(291..1280)
                     /gene="dusB"
                     /locus_tag="ACZPB4_16635"
     CDS             complement(291..1280)
                     /gene="dusB"
                     /locus_tag="ACZPB4_16635"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HIR1099877.1"
                     /translation="MKIGSIDLGERPVFLAPMEDVTDISFRLMCKRFGADMVYTEFVS
                     SDALIRSVNKTQQKLNVSDDERPVAIQIYGKDVASMVEAARICEEAHPDILDINFGCP
                     VKKVAGKGAGAGMLRNIPLMLEITREVVKAVNIPVTVKTRLGWDADNRVIVDLAEQLQ
                     DCGIAALSIHGRTRAQMYTGEADWTLIGAVKNNPRMQIPIIGNGDVTSAEICKQRFED
                     YGVDAVMIGRASIGRPWIFREIKHYLTTGKLLPQEPFSWYLDILKKQVEQSVERLDER
                     RGILHIRRHLAATPLFKGITDFKQTRIAMLRAETVNELFEIMNNIPKKYGILE"
     gene            1560..2819
                     /locus_tag="ACZPB4_16640"
     CDS             1560..2819
                     /locus_tag="ACZPB4_16640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
                     /protein_id="HIR1099878.1"
                     /translation="MKEKDFEIMAPVGSYESLMAAIQGGADSIYFGIEGLNMRSRSSN
                     NFTTEDLRKIVAICGEHGIKSYLTVNTVIYGEDLPLMREIIDAAKDAGVSAIIAADVA
                     AMSYANSIGQEVHLSTQLNISNVEALKFYARFADVVVLARELNLKQVHEIYQEIVKQQ
                     IKGPKGELIRIEMFAHGALCMAVSGKCYLSLHEMNASANRGACMQICRRAYTVHDKDS
                     QIELDVENQYIMSPKDLKTIHFMNKMMDAGVRVFKLEGRARGPEYVRLVTECYKEAVK
                     AYCEGTFDEEKIAVWDERLRRVFNRGFWDGYYLGQRLGEWSSKYGSGATRKKVYVARG
                     IKYFSGIGVAEFEMESGSLRVGDEILVTGPTTGAVMQTVDEIRVDLKPVEETVKGERF
                     SIKMSEKIRPSDRLYKMEKVQIEKELR"
     gene            2819..3232
                     /locus_tag="ACZPB4_16645"
     CDS             2819..3232
                     /locus_tag="ACZPB4_16645"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HIR1099879.1"
                     /translation="MKEYIFKLTDKVRDYECDLQGVVNNSNYQHYMEHTRHEFLESLG
                     ENFGAMHEKGIDAFVARVDIQFKNSLRSGDRYTSCLNVYKKGVKLVFEQDIYRESDGA
                     LATKGVVESVVVENGKLTRGEYFDEMLKRIESKQA"
     gene            3233..>3615
                     /locus_tag="ACZPB4_16650"
     CDS             3233..>3615
                     /locus_tag="ACZPB4_16650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HIR1099880.1"
                     /translation="MTDKQIYQIGLTMINGVGDILARHLLEALGDAEAVFTEKRQSLE
                     KISGIGDSIIAEIKRADVLLRAEKELAFAQKNGISIYFLKDMNYPERLRECPDAPVLF
                     YFKGNADLNAAHIISVVGTRRASAYG"
BASE COUNT          942 a          761 c          934 g          978 t
ORIGIN      
        1 tatttaatgt gacctattga caaagatacg ataagtttct tgatttagga tatagagtcc
       61 ggaaaaacaa aaaagccgct agtcccaata tggatgcggc tttttttgct cctcaatgaa
      121 acaatctcac gattcccccc ttgcaaagac ttgttaacct tagatctaaa atactatgaa
      181 aaaaactcga tgcaaatata aggggtttta taatatgcgt caatagtatt tgtaacattt
      241 tattgtaaaa atatcgcaaa taggtttcaa tttgatatat atcaagcttg ttattctaga
      301 attccgtact ttttaggaat attattcata atttcgaata attcgttaac agtctccgca
      361 cgtagcatgg cgatccgtgt ttgcttgaaa tcggtaatac ctttgaagag cggagtagct
      421 gccagatgac ggcgaatatg taagattccc ctacgctcgt ccaatcgttc cacgctttgc
      481 tccacttgtt tttttaggat atccagatac caagagaaag gctcttgtgg caataatttc
      541 ccggtcgtaa gatagtgttt tatctcccgg aagatccaag ggcggcctat gctagcccta
      601 ccgatcatta cggcgtctac gccatagtcc tcgaaacgct gcttgcatat ctcggcggaa
      661 gtcacgtcgc cattcccgat gatagggatt tgcatgcgag ggttattttt tacggcaccg
      721 atcaaggtcc aatccgcctc gcccgtgtac atttgcgccc gtgtacgtcc gtggatggag
      781 agggcggcga taccgcagtc ctgtagttgc tcggccagat ccacgataac gcggttgtcg
      841 gcatcccatc ccaaacgggt tttcacggtg acggggatgt tcacggcttt caccacctct
      901 ctcgtgatct ccagcatcaa cgggatattg cgtagcatgc cggccccggc tcccttgcct
      961 gctactttct ttacggggca accaaagttt atatctaaaa tatccggatg agcttcctcg
     1021 caaatacgtg cggcctctac catcgaggct acgtccttac cgtaaatctg gatagcgacc
     1081 ggacgctcat catcggagac atttagtttt tgctgtgttt tgttcacact gcggatcaac
     1141 gcgtcgctcg atacgaactc cgtatatacc atgtccgccc cgaagcgttt gcacatcaaa
     1201 cgaaacgaga tatccgtcac gtcctccata ggcgccaaga ataccggacg ctcccctaaa
     1261 tctattgaac caatcttcat accttctgtt tgctaactaa atagagatta caaaagtact
     1321 tctttttggg gaataatttt tacatctcgt aagatgatcg gtggatggaa caggtgtttt
     1381 taataatccg gatcatttat gatatattga tagagttcgg attgccccgc tttatttagg
     1441 atcttgtgct tctccaactg gaactattct ttcatgatgg gatggagggt ttgtgcttat
     1501 aagaaatctt ctcaaatatt attcgtacct ttgctaccgt aatattaaaa tatataacct
     1561 tgaaagagaa ggattttgaa ataatggcgc ctgtcggttc ctatgaatcg ttgatggctg
     1621 ctatacaagg aggggccgac tccatttatt tcggtatcga aggattgaat atgcgttctc
     1681 gctcgtcgaa taatttcacg acggaggatt tgcgcaagat cgtcgctatt tgcggggaac
     1741 atggtatcaa gagttatctc acggttaata cggttattta tggtgaggat cttccgttga
     1801 tgagggagat catagacgcc gctaaggatg cgggtgtctc cgccattatc gccgccgatg
     1861 tagccgctat gagttacgcg aatagcatcg ggcaagaggt gcacttatcc acgcaattga
     1921 atatctcgaa cgtggaggcg ttgaagtttt acgcccgctt cgccgatgtg gtcgtattgg
     1981 ctcgcgaatt gaacttaaag caggtgcatg agatttatca ggagatcgtg aagcagcaga
     2041 tcaagggccc gaaaggggaa ttgatccgca tagagatgtt cgctcacggg gctttgtgca
     2101 tggccgtgtc cggtaaatgc tatttgagtt tgcatgagat gaacgcttcc gccaaccggg
     2161 gggcttgcat gcaaatttgt cgtcgtgcct atacggtgca tgataaggat agccagatcg
     2221 agctggatgt ggagaatcag tatatcatgt cgccaaagga cttgaagacg attcatttca
     2281 tgaataagat gatggatgcc ggcgtacgtg tgttcaagct ggaggggcgt gcccgcgggc
     2341 cggagtatgt gcgtctcgtg accgaatgtt ataaagaggc ggtcaaggct tattgcgaag
     2401 gtaccttcga tgaggaaaag atagcggttt gggacgagcg tctgcgcagg gtctttaatc
     2461 gcggtttctg ggatggctac tatctgggac aacggttggg tgaatggagc agtaaatatg
     2521 gctccggtgc tacccgtaaa aaagtgtacg tggcacgggg tatcaaatac ttcagcggaa
     2581 tcggtgtcgc cgagtttgag atggagtccg gttccttgag agtaggcgat gagatcttgg
     2641 taacgggtcc cacgaccgga gccgttatgc agaccgtcga tgagatccgg gtagacctga
     2701 aaccggtgga ggagaccgtg aaaggggaac gcttctcgat aaagatgtcc gagaagatcc
     2761 gcccgtccga tcgtctttat aaaatggaga aagtacaaat cgaaaaagaa ctacgataat
     2821 gaaggaatat atttttaaac tgacagacaa ggttcgcgat tacgagtgcg atttgcaagg
     2881 cgtggtgaat aactccaatt accagcatta tatggagcat acccggcatg agtttctaga
     2941 gtcgttgggt gagaacttcg gcgccatgca tgagaagggc atcgatgctt ttgtggcccg
     3001 tgtggatatc cagttcaaga actccttgcg gagcggcgat cggtatactt cttgcctgaa
     3061 tgtatataag aaaggggtga aactggtgtt cgagcaagat atttaccggg aatccgatgg
     3121 ggcgctggct actaaaggag tcgtggaatc cgttgtcgta gagaatggca aattaaccag
     3181 aggagaatat ttcgatgaga tgctaaagcg aatagaatca aaacaagcat aaatgacaga
     3241 caaacagatt taccaaattg gccttactat gattaatggg gtgggagata tcctagcccg
     3301 ccatcttctg gaagcgttgg gagatgcgga ggccgtgttt acggaaaagc gccagtcgct
     3361 agagaagata tcgggtatcg gcgattcgat tatcgccgag attaagcggg cggatgtgct
     3421 tttacgggca gagaaagaat tggcttttgc ccaaaagaac ggtatctcta tctatttctt
     3481 gaaagatatg aattatccgg aacgtctgcg ggaatgcccg gacgctccgg ttttatttta
     3541 tttcaagggg aacgcggatt taaacgccgc ccatatcatc agcgttgtgg gtactcgtag
     3601 ggcctccgct tatgg
//
LOCUS       DBMDTB010000186         3524 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_6074_length_3524_cov_9.840783, whole genome shotgun sequence.
ACCESSION   DBMDTB010000186 DBMDTB010000000
VERSION     DBMDTB010000186.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 3524)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 3524)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3524
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_6074_length_3524_cov_9.840783"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            418..1749
                     /locus_tag="ACZPB4_16655"
     CDS             418..1749
                     /locus_tag="ACZPB4_16655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C10 family peptidase"
                     /protein_id="HIR1099881.1"
                     /translation="MKATDTLLSTIIIGVTLIIMTGCSQSEDLIDAGAQALNAATNND
                     KELVLTASEQIALSVKQKGSYNISEKEAKKNFESYAKTIHKEKAVKVKALSLKKNKKN
                     GRNLYYEVIFENDKGTGFSLLSADERVDKLLCYSENGSISDTSFNKSLKYCLELVDLY
                     VEEQTQKELDIESLASSANQKIKTANKGKAITKALPPFDPDDPNSPWSYDRTDVKNEV
                     TERIKQVHAGWHQESPFNDLLPLLPPDYTQRAYTGCAMVAVSQIMAYHQKPYSNYITA
                     VMWPTMIDNRYTSVELKRLMLDLFNTMNTGYDANGTSSNISKARDFLNNNGYTAGSAQ
                     DYTFDRAWSALSYGPTYINGTRAGGNGHAWVIDGVRITKTTSTDIYTITYNGKVFEAS
                     GSSSITSFRTVRYDWGWNRPNDNTWFNSGIFTMPSSGNNYNQSNKIISYVY"
     gene            1771..2445
                     /locus_tag="ACZPB4_16660"
     CDS             1771..2445
                     /locus_tag="ACZPB4_16660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099882.1"
                     /translation="MRNIYFLCCVALASLCACESETKEEPVSDFSDLVIQIVLTDPEL
                     NDRLNPGSPSFLGEEYTQGIEVLYRYKDQKLTLPQLWPLQTNGGAILGEWSTIYPPYM
                     EDNGYGKTDGNTKGYYYIEASPFVTEGNRDIAYTYIQYPDGNEDEIKVQLYRTSSLLL
                     MDQIWINGELVYSMHPQEGSISTKQYYNPEYYPFLVPTLDDDGKQIGDLVQPEGGTSI
                     IVIKKK"
     gene            2665..3474
                     /locus_tag="ACZPB4_16665"
     CDS             2665..3474
                     /locus_tag="ACZPB4_16665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6261 family protein"
                     /protein_id="HIR1099883.1"
                     /translation="MAKITKVKSAYLERLNNAEYRTFMARYGNLLAGGGSDSESPDEI
                     SFDPNDPLGIPQEVRTAFAADFALLTDAVNQSSASEETAQMSTLDKERDDLLIFITST
                     ITQMTKSPLAAQRTAAEKLYLPVKPYIGAARLANLQETAAIEGLLVDLDKDGMPEALA
                     ALTLTEVVASLKEKNQQYAALTEQRTNAQADNPIESAKKIRLRMDEEYDEMTTYAFAQ
                     SVVKPTATTATFINRLNTLIDETNALYNQRIAQARAAAAKKQADSESPSEI"
BASE COUNT         1072 a          903 c          794 g          755 t
ORIGIN      
        1 caaaacggca tggtaaacag caccatgaag atcgtccggg gcaaggtaga gaaagcctac
       61 gccgcccgta tcgcccagct ctatactccc gaggggaaga acccgctgaa caagtggaac
      121 aaggaggcgt tgtagagacg cggcgtgccg catctcatcc cccgcgatgg gccttgctac
      181 cccggcaagg cctttgttgt ttcaagaggg ccgcgacaaa tggataataa cgagatttca
      241 tacaagattc tgatcacaga atttgttttt atccgattta atccagacct ttacgactca
      301 acatttacct attctattca aagaataacc ggtcccgtct cttcggagtt ccttctcaag
      361 atcaacaaag gttgataatc acttttttct catgctaatc tctaaatcca atctcacatg
      421 aaagcaacgg atactttact gagtacgatt attatcggcg ttactttaat aatcatgacg
      481 ggatgttcac aaagtgaaga tcttatagat gctggcgccc aagcgttaaa cgcagcgaca
      541 aacaatgaca aggagttggt cttaaccgcc tccgagcaaa tcgccctttc cgtaaaacag
      601 aaaggttcat acaatatctc ggaaaaagaa gcgaaaaaga acttcgagag ctatgctaag
      661 accatccaca aggagaaagc cgtaaaagta aaagctctct cattgaagaa gaacaagaaa
      721 aacgggagaa acctatatta cgaagttata ttcgaaaacg acaaaggaac gggattctcc
      781 ctattatcgg cagatgaacg tgtagacaag ctactttgtt actcagaaaa cgggtctata
      841 tcggacacct cgtttaacaa gagcttgaaa tactgcctag agctagtcga tttgtatgtg
      901 gaggagcaaa cccaaaagga attagacata gaaagtctgg cctcttcggc gaatcaaaag
      961 ataaaaacgg caaataaagg caaggcaatc accaaagcgc tcccaccttt tgaccccgac
     1021 gacccgaaca gcccttggag ttatgaccgg acagacgtaa aaaacgaagt caccgaaagg
     1081 atcaagcaag ttcacgcagg atggcatcag gaaagtccat tcaacgattt attaccattg
     1141 cttcctcccg attatacgca aagagcctat acgggttgtg ctatggtagc cgtctcgcaa
     1201 atcatggcat atcaccaaaa gccctacagc aattatatca cggcggtgat gtggcctaca
     1261 atgattgata atagatatac atccgtagaa ctaaagcgcc ttatgcttga tttgtttaat
     1321 acgatgaaca caggatatga tgcgaacggg acaagtagca atatatccaa agccagagac
     1381 ttcctaaata ataacggcta taccgccgga tccgctcaag attatacatt tgacagggct
     1441 tggagcgcat taagctatgg ccctacgtat ataaatggaa caagagctgg cggtaacggt
     1501 catgcttggg tcattgatgg agtacgaatc acgaaaacta ccagtaccga tatctatacc
     1561 attacatata acgggaaagt gtttgaagct tccggtagtt cttccatcac ttcctttcga
     1621 accgtccggt atgattgggg atggaatcgt ccgaacgata acacttggtt taacagcggt
     1681 attttcacga tgccatcttc tggaaacaat tacaatcaga gtaacaagat aatcagttat
     1741 gtttattaat ccatttaaac atcgagtcct atgagaaata tatatttttt atgctgcgtt
     1801 gcgctagcaa gcctctgcgc ttgcgaatcg gaaacaaaag aagagccggt ttctgacttt
     1861 agtgatctag tcatacaaat cgtactgaca gacccggagc tgaacgatcg cctgaacccg
     1921 ggatccccaa gcttccttgg agaagagtat acccaaggaa tagaagtcct gtaccgatat
     1981 aaagatcaaa aattaaccct tccccaactt tggcctctcc agacaaacgg aggagctatc
     2041 ctaggagaat ggagcacgat ctatccacct tatatggaag acaatgggta tgggaagaca
     2101 gatggaaaca cgaaaggata ctattacatc gaagcctctc ctttcgtgac agaaggaaat
     2161 agggatatcg cctataccta tatccagtat cccgacggaa acgaggatga gataaaagta
     2221 cagctataca ggacttcatc cttgctcctt atggatcaga tctggatcaa cggagaacta
     2281 gtttattcca tgcatcctca ggaaggctcc ataagcacga agcagtatta caacccggaa
     2341 tattatccgt tcctcgtccc aacgctggac gacgatggca agcagatcgg ggatctggtg
     2401 cagcccgagg gcggcaccag tatcatcgtg atcaagaaga aatgatttat cgcgaggccc
     2461 ggccaccacg gttgggcccc gctgaaattt ttaaattcca tctcgcgcct aacgcaagcc
     2521 cgatttaaac ttttaaatcc accccgcacc ggatgtaagc ccgattttaa aaaaacaatg
     2581 ccgctcttga tcgatacatc cggaaatctt cttacattag cacaattaaa tcatatatat
     2641 ctatccaact aaaaattttc agacatggca aaaatcacga aagtaaagag cgcatattta
     2701 gaaagattga acaacgccga gtaccgaacc ttcatggccc gctacgggaa cctgctcgcg
     2761 ggtggcggaa gcgactcgga atcgcccgac gagatcagct tcgatccgaa cgacccgctg
     2821 ggcatccccc aagaagttcg tacagccttc gccgccgatt tcgccctatt gaccgacgcc
     2881 gtgaaccaat cctcggccag cgaggagacc gcgcagatgt ccaccctcga caaggagagg
     2941 gatgatctct tgatcttcat tacttccacc attacccaaa tgacgaaaag cccgctggcg
     3001 gcgcaacgca cggcggccga gaagctatac cttcccgtga agccctacat cggagccgcg
     3061 cgcctcgcca acttgcagga gacggccgcc atcgagggct tgctggtaga cctcgacaag
     3121 gacggcatgc ccgaggcgct ggcggcgctc accctcaccg aggtagtggc ctcgctgaag
     3181 gagaagaacc agcaatacgc agccttgacc gagcagcgca ccaacgcgca agccgacaac
     3241 cccatcgaga gcgccaagaa gatccgcctc cgcatggacg aggaatacga cgagatgacc
     3301 acctacgcct tcgcccagag cgtggtgaag ccaacggcta cgaccgccac cttcatcaac
     3361 cgcctcaaca ccctcatcga cgagaccaac gccctctaca accaacgcat cgcacaagcg
     3421 agggccgccg ccgccaagaa gcaagcggat agcgaatcgc cgtcagagat ataaagccgt
     3481 gaggccctca tgttttttag atttaagaat gatggggctc ccct
//
LOCUS       DBMDTB010000187         3521 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_6081_length_3521_cov_8.428363, whole genome shotgun sequence.
ACCESSION   DBMDTB010000187 DBMDTB010000000
VERSION     DBMDTB010000187.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 3521)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 3521)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3521
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_6081_length_3521_cov_8.428363"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..416)
                     /locus_tag="ACZPB4_16670"
     CDS             complement(<1..416)
                     /locus_tag="ACZPB4_16670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="eCIS core domain-containing protein"
                     /protein_id="HIR1099884.1"
                     /translation="MNADRIQIQEGPSQVFQNRKGESTQLMEDNRVQSVLQAKMVETM
                     QRDAMDEDDLQQGKFAVQRDVEDEDELLQGKFVAQRQTKNQTGIPDYVIQGMESSFGT
                     DFSSVRVHPDSSKAPEVGALAYTQGTDIHFAPGQFKP"
     gene            complement(439..>3521)
                     /locus_tag="ACZPB4_16675"
     CDS             complement(439..>3521)
                     /locus_tag="ACZPB4_16675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="contractile injection system tape measure
                     protein"
                     /protein_id="HIR1099885.1"
                     /translation="FVHDLYGRWDTFNRTSLEGIVDEILSRYDTEDELIRIESLDLDL
                     GELEEDEFYEQFPRRLAERLDETFASYLRSKEEHPDRIAVVPIRQSWLEVFTYYMSHG
                     YWPWLEEERLTLPELLDKLVRTSSIELSHFLREKGKALTIRKRLVFQLDDIYQERLVH
                     VVVPSESSFINAYARFLQDSYPEIKRPEIGKNDYRNAIWIILCGYLLSQDQGYFNRKQ
                     MVTYALRELSGYYSIYFVDLLGMLTYDLDKFASTRLFMPELLSLLKDIRLETLSEKEF
                     TKNFSLFSLEELKALLVRREKSLTFLSGYNEEQIYLIVEQVIPAESPFVIDYARALDK
                     EKELGMLEGKAGNDFRVLKWVFIFEVILGRSGSVYSRHQFAFSVLKELAAHYNLTVME
                     LLGYFYRTLASGLLTAYPAVRELIIALYLNAIDDSPAGISVYYPEDLKDRLSNPGLCR
                     CFIRFLREEQIYSVVEQTVPVESHFIIRYAQTLDKGKEQGRLEGRVGDEFRLLKWEFI
                     FLVLFSAPLSAFSRKQFVRSVLGQFSAHYNITVRELISYFHEGTHGEHPWVPEELREI
                     IDLLYEDMDKESPEPLFSVWLNEERKAYRFGQFIITGRADEPLGDLFEYVRDLEKTNP
                     KVLLDQLRQLKDIPSSGIRVEEPIEAARIFASLLLLVIREYGLAFPNQVSLIQYLTNV
                     KENRTFGDAARLRLLLHECMLENMDAFTRTMDALLGTKPGKAPELPIRTAFPAIYPSN
                     SKKMELLEELYTGATPALRLLVEEVIRLFRLNSFGLEENLWLGWLQALSGNVYRNYSK
                     DGLLFLFWQRLRESVPEEELRKIETFIGRHITNLPELSVFIYQLKNNMNMNVLNGQLK
                     DHGVSIDNAGLVIIAVYLPMLFNRLGYLSDDRRDFKSKECQVKAIFVSQCFVTDEKEI
                     PESELFLNKVLTGYDNSPEPLPRSCDLTENELEIMEQLKKAVLMNWDKMRHTSWEGFQ
                     KTFIQRKGMLKMEEDNWMLTVEEKPFDILLDSLPWNFKLVKAPWMEKMLRVKWR"
BASE COUNT          995 a          926 c          668 g          932 t
ORIGIN      
        1 ggtttgaatt gtcccggggc gaaatggata tccgtacctt gcgtatatgc caaagcccca
       61 acctccggcg ctttcgatga atccgggtgt acacgtaccg aagagaaatc cgtcccgaag
      121 gaagactcca tgccttggat tacataatcc ggaatccctg tctggttctt cgtttgccgt
      181 tgggccacaa attttccttg aagaagctca tcctcatctt ccacatcccg ctgaacggcg
      241 aacttacctt gctgcaaatc atcctcatcc atcgcgtcac gttgcatagt ttccaccatt
      301 ttagcctgca agacagattg tacccgatta tcttccatca attgtgttga ttcaccttta
      361 cggttttgaa agacctgcga aggtccttct tgaatctgta tccgatccgc attcataatg
      421 ttatcattta atagtatttt accgccactt tactctaagc attttttcca tccatggagc
      481 tttaacgagc ttgaagttcc aaggaagcga gtctaataag atgtcaaaag gcttctcctc
      541 gaccgttagc atccaattat cctcttccat ttttaacatt ccctttctct ggataaaagt
      601 tttttgaaaa ccttcccagc ttgtatgcct catcttgtcc caattcataa gtaccgcttt
      661 cttcaattgt tccatgatct ccaattcatt ctcggttaaa tcacacgagc gaggaagcgg
      721 ttccgggctg ttgtcatagc ccgtcaagac tttgtttaag aataattctg actccgggat
      781 ttccttctca tccgtcacaa aacattggga cacaaaaata gctttcactt ggcattcttt
      841 cgatttaaag tcacgcctgt catcactcaa gtagcctaac cgattaaaaa gcattggcag
      901 gtagacggct atgatcacta ggcccgcatt gtcaatagac acgccatggt cttttaactg
      961 gccattcaaa acgttcatat tcatattatt tttaagttga tatataaaaa ctgacaattc
     1021 aggtaaatta gttatatgtc gccctataaa agtctcgatc ttacgtaatt cctcctctgg
     1081 cacagactcc ctcaaacgct gccaaaagag gaacaacaat ccatccttgg aataattccg
     1141 gtaaacgttg ccggaaagag cctgtaacca ccccaaccaa aggttctctt ccaacccgaa
     1201 gctattgaga cgaaacaagc ggattacctc ctctacaagt aagcgcaaag cgggagtcgc
     1261 ccctgtatat aattcctcca ataattccat ttttttggaa ttggacggat agatagcggg
     1321 aaaagcagta cggatgggaa gctcgggcgc tttccccggt ttcgtgccca gtaaagcatc
     1381 catggtacgt gtaaacgcat ccatattctc caacatacac tcatgcaata acaagcgcag
     1441 ccgagcagca tctccaaatg tacgattctc ttttacattc gtaaggtatt ggatcaagga
     1501 tacctgattc ggaaaagcca gaccgtattc acggatgaca agcagtaata aggaagcgaa
     1561 gatacgagcg gcctctatcg gttcttccac ccttattccg gatgaaggaa tatccttcaa
     1621 ttgccgtaat tggtccagta agactttcgg gttcgtcttc tccaagtccc tcacgtactc
     1681 gaatagatcg cccagcggtt catcggcacg gcccgtgatt ataaattgcc cgaaccgata
     1741 ggctttcctc tcctcattca accaaacaga gaataaaggc tcgggagatt ccttatccat
     1801 atcctcgtac agcagatcta ttatctcacg taactcttcc gggacccatg gatgttcccc
     1861 atgtgttccc tcatggaaat aggagatcag ctcccgcacc gtgatattat aatgggcaga
     1921 gaactgtccc aacaccgaac gtacgaattg tttccggcta aaagcggaca atggcgcact
     1981 aaacagcacc agaaagataa attcccattt caacagccgg aactcgtcac ccacccttcc
     2041 ttccaaacgc ccttgctctt tccccttatc cagcgtctgg gcataccgta taatgaaatg
     2101 gctttccacc ggaacggttt gctcgaccac cgaatagatt tgctcctcgc gcaagaaacg
     2161 gataaagcaa cggcacaagc cgggattaga caaccgatct ttcaaatctt ccgggtaata
     2221 aacggatata ccggcgggag aatcatcgat agcattcaag tacaaagcaa tgatcaattc
     2281 ccgaacggct ggataagccg ttagcagtcc actagccaag gtacggtaaa aatatcccaa
     2341 caactccatc accgtcagat tataatgcgc cgccaactcc tttaacacgg agaaagcgaa
     2401 ctgatggcgg gaatatacgc ttccacttct accgagaata acctcgaaga taaacaccca
     2461 tttcagcacc cggaaatcat tcccggcttt cccttcgagc atgcccaatt ccttctcctt
     2521 atccaacgct ctcgcatagt cgatgacaaa cggactctcc gcagggatca cctgttccac
     2581 gatcaggtaa atctgttcct cattataccc ggataagaaa gtcaagctct tctcccgccg
     2641 cacgagcaaa gccttcaatt cttccagaga aaaaagagag aaatttttag tgaattcctt
     2701 ttccgataat gtctctagcc ggatatcctt caaaagcgac agtaactcgg gcatgaacaa
     2761 gcgggtagag gcgaacttat ctaaatcata cgtcagcatc cccagtaaat ccacaaaata
     2821 aatggaataa tagccggata attcccgcag tgcgtacgtc accatttgtt tccggttgaa
     2881 atagccttga tcctgagata ataaatatcc acataggatt atccagatag cgtttctgta
     2941 atcattcttc cctatctccg gacgctttat ctcgggataa gagtcttgca agaaacgggc
     3001 ataagcgttt ataaacgagc tttccgaggg taccaccaca tgtaccaaac gttcttgata
     3061 gatatcatcc aattgaaaga ctagacgttt acgaatggta agcgcctttc ccttctcacg
     3121 caggaaatga cttaattcta tcgaagatgt tcgtactaat ttatccagaa gctccggtaa
     3181 ggtgagtcgc tcctcttcca gccaaggcca atacccgtgc gacatataat aggtaaatac
     3241 ttccagccaa gattgcctga tgggaacaac tgctattcgg tctggatgct cttctttact
     3301 tcgcaaataa gaagcgaaag tctcgtccag tctctccgcc agtctacggg ggaattgctc
     3361 atagaattca tcttcttcta gctcacctag atccaaatct aaactctcga tccggatcaa
     3421 ctcatcttcc gtatcataac ggcttaaaat ctcatccacg atcccttcta aagaggttcg
     3481 gttaaaggta tcccaacgac catataaatc atgaacgaaa g
//
LOCUS       DBMDTB010000188         3482 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_6165_length_3482_cov_10.193730, whole genome shotgun sequence.
ACCESSION   DBMDTB010000188 DBMDTB010000000
VERSION     DBMDTB010000188.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 3482)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 3482)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3482
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_6165_length_3482_cov_10.193730"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(49..1707)
                     /locus_tag="ACZPB4_16680"
     CDS             complement(49..1707)
                     /locus_tag="ACZPB4_16680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HIR1099886.1"
                     /translation="MENRFLGLIENSIKEHWDLPAFSDYNGHTFHYKDVARRIEKFHI
                     ILEHAGIKKGDKVALVGRNSSNWAICFFGILAYGAVAVPILHEFKPDNIHHIVNHSEA
                     KAVLAASSNWENMNERMMPDVKLFMMLDNFSIIHSKSKEVRVVRDRINEYFGKKYPRS
                     FTSNDVRYHVEKPEELAVLNYTSGTTSFSKGVMIPYRSLWSNTQFAYDNLPFIHPGDN
                     IVCMLPMAHMYGLAFEVLNSVNKGCHVHFLTRTPSPKIIAEAFTTIKPALILAVPLII
                     EKIIKNKVFPELEKPLIKLLLKVPYIDQKVLDTISAKLTASFGGNFGEIVIGGAAINK
                     EVETFLHSIHFRYTVGYGMTECGPLVSYAQWDEFKPGSVGRIVDRMEVRIDSEDPENK
                     VGEILVKGMNVMLGYYKNPEATKAVMMPDGWMRTGDLGTLDKDGFLYIRGRSKTMILG
                     PSGQNIYPEEIEDRLNNMLYVAESLIISQGGKLVALIYPDWEQVDKAGIQHSEIEKLM
                     QTNIDQVNEEMPNYSKITCFKLYQEEFEKTPKRSIKRYLYQPAE"
     gene            1848..2648
                     /gene="mtgA"
                     /locus_tag="ACZPB4_16685"
     CDS             1848..2648
                     /gene="mtgA"
                     /locus_tag="ACZPB4_16685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009274 - peptidoglycan-based cell wall
                     [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="monofunctional biosynthetic peptidoglycan
                     transglycosylase"
                     /protein_id="HIR1099887.1"
                     /translation="MVAPLVKRIWIWCRNLLIFLFVSSILAVVVYKFVPVYYTPLMFI
                     RMYEQHQDGKKMKLGHTWVPISKIAQPLVQAVIASEDNLFMEHNGFDVEQIQKARAEA
                     EKGKRVRGASTISQQTAKNVFLWPGKSYLRKGIEVYFTFLIEWIWGKERIMEVYLNSI
                     EMGEGIYGAEAVAEAHFGKHAYQLTKSEAALIAATLPNPRKFNSAKPSPYMLKRQAKI
                     ISLMGKLIKVEMGYGAGQVDPGTGKVKKRKKWRASVIMTWDESLMPMR"
     gene            2594..3259
                     /gene="lipB"
                     /locus_tag="ACZPB4_16690"
     CDS             2594..3259
                     /gene="lipB"
                     /locus_tag="ACZPB4_16690"
                     /EC_number="2.3.1.181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033819 - lipoyl(octanoyl) transferase
                     activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoyl(octanoyl) transferase LipB"
                     /protein_id="HIR1099888.1"
                     /translation="MESFRYHDLGRIAYADALEYQTAAFEVLLDAKATGKKEDNQLFF
                     CEHLPVLTIGKSGKDSNLLIPEETLRERGVSFYHINRGGDITYHGPGQITGYPVFDLE
                     YWNLGLKQYIHMLEETIIRFLSLYDLKGERLEGATGVWLDPEVPGRARKICAIGVKSS
                     RFVTMHGFALNINTDLSYFSLINPCGFTDKGVTSLAMELGVPQDFELAKSQLRSIFME
                     IFA"
     gene            3261..>3482
                     /locus_tag="ACZPB4_16695"
     CDS             3261..>3482
                     /locus_tag="ACZPB4_16695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase family protein"
                     /protein_id="HIR1099889.1"
                     /translation="MAVIHFAPLQGYTDSVYREAHTRVFGGVDTYYTPFVRIEKGGFR
                     NKDLKDIACDRNRQVHVVPQLIASTPDEFR"
BASE COUNT          926 a          721 c          840 g          995 t
ORIGIN      
        1 tttactttat ataaaagaag ccgtctttaa caaaagacgg ctttcttttt attcggccgg
       61 ttggtataaa tatctcttga tgcttctttt gggtgttttc tcgaattctt cttgatacag
      121 cttgaaacag gtgattttac tgtaattcgg catctcctcg tttacttggt caatgttggt
      181 ctgcatcaac ttctcgattt cggaatgttg tatacctgcc ttatctactt gctcccaatc
      241 gggatagatg agggcgacta gtttacctcc ttgggagatg atgagcgatt ccgctacata
      301 tagcatatta ttcaagcgat cctcgatctc ttccggatag atattttgtc cgctggggcc
      361 tagaatcatg gttttactac ggccgcggat atataaaaat ccatctttat cgagggttcc
      421 cagatcgccg gtacgcatcc atccgtcagg catcataacg gctttcgtag cctccggatt
      481 cttgtaataa ccgagcatca cgttcatacc cttcaccaat atttctccca ccttgttttc
      541 cgggtcctct gaatcgatgc ggacttccat acggtcgacg atacgtccta cggaaccggg
      601 cttaaactca tcccattgcg cataggagac tagcgggcca cattcggtca tcccgtagcc
      661 tacggtatag cggaaatgga tggaatgaag gaacgtttcc acttctttat tgatagcggc
      721 tcctccgata acgatctccc cgaagtttcc tccgaaagac gccgttaact tggcggaaat
      781 ggtatccagt actttctggt ctatataggg gactttcaag agcaatttaa tcaaaggctt
      841 ctccagttcg gggaatacct tgtttttgat gattttctcg ataatcagag gtacggctag
      901 gatcagcgcc ggcttgatcg tcgtgaaagc ttccgctatg attttcgggc tgggggtacg
      961 tgtgaggaag tgtacatggc agcctttatt cacggaattc aatacctcga atgccaatcc
     1021 gtacatatgg gccatcggaa gcatacatac gatattatca cccggatgga tgaacggtaa
     1081 attgtcgtaa gcgaattgcg tattactcca taagctccga taggggatca taaccccttt
     1141 cgagaaactg gtggttccgg aagtataatt aagtaccgct aattcttccg gcttttccac
     1201 gtgataccga acatcgttcg acgtgaatga acgagggtac tttttaccga aatattcatt
     1261 aatccgatct cttactaccc ggacttcttt gcttttactg tgaatgatcg agaagttatc
     1321 cagcatcatg aacagtttca cgtcgggcat catgcgttca ttcatattct cccagttgct
     1381 ggaagcggca aggactgcct ttgcctcgga atgatttacg atatgatgta tattatccgg
     1441 tttgaattca tgtagaatag gcacggctac ggctccataa gccaagatcc cgaagaaaca
     1501 gatcgcccag ttggaggagt tccgtccaac taaagccacc ttatccccct ttttaatgcc
     1561 ggcatgctct aggataatat gaaatttctc gattcgacga gctacatctt tataatggaa
     1621 ggtatgtcca ttataatcgg agaacgccgg gagatcccaa tgctccttga tgctattctc
     1681 tatgagtcct aaaaaacgat tctccatact aatttattta tcaaataacc atatgacagg
     1741 gtggaaagtt gtcaaaagcc aaagatagtg ccttttctgt aaattatgag tttcagtctg
     1801 ccggaaactg aaatattctt tacctttgtc tctccaaata gaagaatatg gtagcacctc
     1861 tggtaaaacg gatatggatc tggtgcagga atctgttgat cttcctgttt gtatccagta
     1921 tattggcggt agtggtatat aaatttgtac ccgtatatta tacgccattg atgtttattc
     1981 gtatgtatga gcagcatcag gatgggaaga aaatgaaact cggtcatacg tgggttccta
     2041 tatccaagat cgcccagcct ttggttcaag cggtcatagc gtcggaggat aacctgttca
     2101 tggagcataa tggctttgat gtggaacaaa tccagaaggc acgggccgag gccgagaaag
     2161 gtaaaagggt aagaggtgcc agcacgattt cccagcagac cgctaagaat gtatttcttt
     2221 ggccggggaa aagttattta cggaaaggta tcgaggtcta ttttaccttc ttgatcgaat
     2281 ggatatgggg aaaggaacgt attatggaag tctatctgaa ctcgatagag atgggggagg
     2341 gtatctatgg tgcggaggcg gtagcggagg ctcatttcgg taagcatgcc taccaattga
     2401 ccaaaagcga ggcagccttg atagcggcca cacttccaaa tccccggaag tttaattctg
     2461 ctaaaccgtc accttatatg ctgaaacgac aagcgaaaat aatttcctta atgggaaaac
     2521 tgataaaagt agaaatggga tatggtgccg ggcaagttga tcccggtacc ggaaaggtta
     2581 aaaaaagaaa gaaatggaga gcttccgtta tcatgacttg ggacgaatcg cttatgccga
     2641 tgcgttagaa tatcagacag ctgctttcga ggtcttattg gatgcgaagg caacgggaaa
     2701 gaaagaggat aatcaattat tcttttgtga gcatttaccg gtcttgacga tcggtaaaag
     2761 tggcaaggac tctaatttgc ttattcccga ggaaacttta cgggaacgag gggtctcgtt
     2821 ttaccatata aacagagggg gggatataac gtatcacggg ccgggacaga ttaccggtta
     2881 tccggtattt gatctggaat attggaatct gggattgaaa caatacatcc atatgctgga
     2941 agagacgatc atccgtttcc tatcgcttta cgacttgaaa ggggaacgtt tggaaggggc
     3001 gacgggtgta tggctagacc ctgaagtacc ggggcgtgcc cgtaagatct gtgcgattgg
     3061 cgtgaaaagc agccggttcg ttacgatgca tggctttgct ttgaatataa atacggatct
     3121 gagttacttt tcattgatca acccttgtgg ttttacggat aaaggcgtta cctccttggc
     3181 tatggagttg ggggtacccc aagactttga gttggcaaaa agtcaattga gatcgatttt
     3241 catggaaatt ttcgcttgat atggcagtca ttcatttcgc tcctttgcaa ggatatacgg
     3301 attcggttta tagagaggcg catacccgag tattcggggg cgtagatacc tattatactc
     3361 ctttcgtaag gatagagaaa ggtggtttcc ggaataagga cttgaaggat atcgcttgcg
     3421 atagaaatag gcaggtacat gtcgtaccgc aattgatcgc ttccacacca gacgagtttc
     3481 gg
//
LOCUS       DBMDTB010000189         3437 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_6252_length_3437_cov_11.844724, whole genome shotgun sequence.
ACCESSION   DBMDTB010000189 DBMDTB010000000
VERSION     DBMDTB010000189.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 3437)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 3437)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3437
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_6252_length_3437_cov_11.844724"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..1404)
                     /locus_tag="ACZPB4_16700"
     CDS             complement(<1..1404)
                     /locus_tag="ACZPB4_16700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005848678.1"
                     /note="Members of this family are fimbrial shaft proteins
                     (major subunit proteins), found in the Bacteriodetes. The
                     family is named for Mfa1 from Porphyromonas gingivalis,
                     and is related to but distinct from the family of FimA
                     from the species; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0009418 - pilus shaft [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Mfa1 family fimbria major subunit"
                     /protein_id="HIR1099890.1"
                     /translation="MKGKKFLLAGVAILGLGMTSCNNDDVPSVGNPTEGSTFVGMYIS
                     TMKDVMTRAVNDSQGDYAGRADESTLESLRLISLGTPRDWTLGSADEENKFWETTPAG
                     TYTVAPWKATSGSQAMALLFNRGSLNPGIATATNEEYGSAATAVADIAALATDKKFVM
                     TSKAEQKTIKDNISEETVKTGTGEAQNVFSFDMERVVSQGMVTKGGDLNAETADGKGS
                     VDLDNLTYAAINGAAKTYLFRNHAGDRTITAGDGLYKDFTSAIDDYADFQNAQDPNGT
                     AKDYLIRLGNLLPEETSTADDLGMYAAKAVAADATEAKKVAGIYFLENSVKKEALTPD
                     NKNFGYYRLPYAKVYTTYTPKEVLHWDQDQKKLISKPGVKGETFYRGEGDGLIYASKE
                     AAKKSQLSPDQGAYTYTNGRCAYRALWNRQTNADGKTIVNANTRRNNTYLLTITAFQG
                     LGMPWDPSDPKDPYLPKP"
     gene            complement(1459..2817)
                     /locus_tag="ACZPB4_16705"
     CDS             complement(1459..2817)
                     /locus_tag="ACZPB4_16705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099891.1"
                     /translation="MRVKRSANGKSLRFSLHVDAMTRLESQDVLVIYPSLVSASGDDR
                     IDFAPVGIAGRIRYKAITRSKALGENSRTSRFDNELHPFSDIEEQGGSFQESVPFERW
                     MADGHVTVREELLGCVGCGIRENQGTVAVIDLPVFKEEDYAYDFLEPEKVAVKYYKDS
                     FDSKVTFPVASYELRKAFANNGQELARLEGFISRSLEIKGAELKEVLIEGFASPEGKA
                     EYNQSLAEGRTLALSNYISGKYPGLKKAATYRTVGAGEDWEGLKKLVGISPLSNKEEL
                     LSIIDRYPTDTERESAIRNLDNGRTYGILLKEFYPQLRRTTFRFSFDVRAYTQEELPE
                     IFATRPECLSSHEMYQLSEIYLMRGENPLPVFQKAYEQFPEDVVVTLNYANALLKYGK
                     KADGALRVLSDVRNDSRALFPMAVAYHIKGDWRKAEELLKEAYKQGDDRARAFYGEDA
                     YE"
     gene            complement(2991..>3437)
                     /locus_tag="ACZPB4_16710"
     CDS             complement(2991..>3437)
                     /locus_tag="ACZPB4_16710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3575 domain-containing protein"
                     /protein_id="HIR1099892.1"
                     /translation="TQVGMNFFFYENDPTADGYKTRKWSHWLVQPEIRYWACERFNGW
                     FLGLHAHGGQMNVGGINIPFILQNKHKEMKAHRYEGYFYGGGISAGYHWILSDRLNFE
                     AALGIGYAHVRYDKFKCTACGQRTGKGGADYLGPTRVSLSIIYILK"
BASE COUNT          783 a          944 c          765 g          945 t
ORIGIN      
        1 aggcttcggc agatacggat ctttaggatc ggaaggatcc cacggcatac ctaggccctg
       61 gaaagccgta attgtcaaca gataggtgtt gttacgacga gtattagcgt tcacaatcgt
      121 ttttccatca gcgtttgttt gacggttcca caacgcacgg tacgcgcatc ttccgttcgt
      181 ataggtatag gctccttgat ccgggctcaa ctggcttttc tttgcggctt ccttgctggc
      241 atagatcagc ccatcgcctt ctcctcgata gaacgtctcg ccctttaccc cgggtttact
      301 gattaacttc ttttgatctt gatcccaatg caatacctct tttggagtat aagtcgtata
      361 gaccttggca tacggtaggc gatagtaacc gaaattctta ttgtcaggtg tgagtgcctc
      421 cttttttacg gaattctcca agaaataaat acctgccacc tttttagcct cggtagcatc
      481 tgccgcaacc gccttggccg cgtacatgcc aagatcatcc gctgttgaag tctcttccgg
      541 caagaggttt cccaagcgga tcaaataatc cttggctgta ccgttcggat cttgggcatt
      601 ttgaaaatca gcatagtcat caatagcgga tgtgaaatct ttgtaaagcc cgtctcccgc
      661 tgtgattgta cgatctcctg catggttgcg gaaaagatat gtctttgcgg cgccgttgat
      721 agccgcatac gtgaggttat caagatcaac acttcctttt ccgtcagctg tttccgcatt
      781 taggtctccc ccttttgtga ccatgccttg cgacacgaca cgttccatgt caaaggagaa
      841 tacattctga gcctctcccg tgcctgtctt gactgtttcc tcggagatat tgtccttgat
      901 ggttttctgc tcggccttcg aggtcatcac gaacttttta tccgtggcga gagccgcgat
      961 gtcggccacc gcggtagccg cacttccata ctcctcgttc gtggccgttg cgataccggg
     1021 attaagagag cccctgttaa acaacaacgc cattgcttgg gagcccgagg tggctttcca
     1081 tggggcgacc gtgtaagttc cggccggtgt cgtttcccag aatttattct cctcgtcagc
     1141 gcttcctagc gtccagtccc gaggcgtacc aagagagata agccgtaaag actcaagcgt
     1201 gctctcatct gctctacccg cgtaatctcc ctggctgtca tttaccgccc tggtcatgac
     1261 atctttcatg gtagagatgt acattcctac gaatgtactt ccttcggtag gattccctac
     1321 cgaaggaaca tcgtcattat tacaggacgt catgcctaaa cctaggatag caacgcctgc
     1381 taaaagaaat ttttttcctt tcataactta aaaattagtg aataaataaa ttaactgttg
     1441 ttatataaag tcttaacttt attcataagc gtcttcgcca tagaaagccc tggcacggtc
     1501 atccccctgc ttataagcct ccttcagcaa ttcttccgcc tttctccagt cccctttgat
     1561 atgataggcg accgccatcg ggaaaagggc ccggctgtcg ttcctcacgt cgctcaacac
     1621 ccgtaaggca ccgtccgcct ttttcccgta ttttagcaag gcgttggcat agtttagtgt
     1681 cactaccaca tcctcaggaa actgttcgta cgccttttgg aagacaggga gaggattctc
     1741 cccccgcatg agatatattt ccgagagttg gtacatctcg tgtgagctca gacattccgg
     1801 cctcgtggca aatatttcag gtaactcctc ctgggtataa gcccttacgt cgaaactgaa
     1861 acgaaaggtc gtacggcgga gttgcggata aaactctttt aggaggatgc cgtaggtcct
     1921 gccgttgtcc aagttacgta tggcggactc tcgctccgta tccgttggat atcggtctat
     1981 gatagacagc aattcctctt tattggacag gggagaaata cctacgagct ttttaaggcc
     2041 ctcccaatcc tctccggcac cgaccgtccg gtaagtcgcg gcctttttaa gcccggggta
     2101 ttttccggag atataattcg agagcgctag ggtacgccct tccgccagtg actggttata
     2161 ttccgcttta ccctcgggag aggcgaagcc ctctatgagg acctctttta actcggcccc
     2221 ttttatttcc agacttcttg atatgaatcc ttccagccgg gcgagctcct gcccgttatt
     2281 cgcgaaggcc tttctcagtt cgtagctcgc tacgggaaaa gtgaccttgc tgtcaaagga
     2341 gtctttataa tacttgaccg ccaccttttc cggctcgagg aaatcatacg cataatcctc
     2401 ctccttgaaa acaggcaggt caatgacagc cacggtacct tgattctcac gtatgccaca
     2461 acccacgcaa ccgagcagtt cctctctcac cgtaacatgg ccatccgcca tccagcgttc
     2521 gaacgggacg gattcctgaa aggaaccccc ctgctcctct atgtccgaaa aaggatggag
     2581 ctcattgtcg aaccgagatg tcctggaatt ctcaccgaga gccttcgacc gcgtaatagc
     2641 cttatatcgt atcctgcccg caataccgac aggcgcgaaa tcgatcctgt catccccact
     2701 ggcggaaacc agtgatggat agatgacaag aacgtcctgt gactccaacc gggtcatggc
     2761 gtccacatgc agggaaaaac gcaggctttt tccgtttgcg ctccgcttga ccctcacgtc
     2821 atatctctaa tgtaatggtg ataggttccg ctcaacgacc tcctgggcct gcccgaatat
     2881 agccgtcaaa ccaaggcagg cacagactgc tgacagcttt atgtaataat gcatcgatct
     2941 cattcacttc atatttttat atcttatact aattttgccc aaggcctgtt ttatttaagt
     3001 atataaataa ttgagagaga gactcttgtc gggccgaggt aatcggcgcc tcccttcccc
     3061 gtcctttgtc cgcaagccgt acatttgaac ttgtcatatc tcacgtgcgc gtatcctatc
     3121 cccaaagcgg cttcaaaatt gagtctgtcg gataaaatcc aatgataacc ggcactgatg
     3181 ccgccaccgt agaaatagcc ttcataacgg tgcgccttca tctctttatg cttgttctga
     3241 agaataaaag ggatgtttat cccaccgaca ttcatctggc ctccatgcgc gtgcagcccg
     3301 agaaaccaac cgttgaatct ctcgcaagcc caatatcgta tctcgggttg cacaagccaa
     3361 tggctccatt tccttgtctt gtatccatct gcggtgggat cgttctcata gaagaaaaaa
     3421 ttcatgccca cctgggt
//
LOCUS       DBMDTB010000190         3363 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_6398_length_3363_cov_8.764562, whole genome shotgun sequence.
ACCESSION   DBMDTB010000190 DBMDTB010000000
VERSION     DBMDTB010000190.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 3363)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 3363)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3363
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_6398_length_3363_cov_8.764562"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(253..1647)
                     /locus_tag="ACZPB4_16715"
     CDS             complement(253..1647)
                     /locus_tag="ACZPB4_16715"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HIR1099893.1"
                     /translation="MSNNNIDRRNFLKVLSTGTAAASTGLLYGCGGDPKRQGVSQTGS
                     YLGEVPTDKMTYRTNPHTGDKVSLLGYGCMRWPLRQKADGSGEEIDQEAVNALVDYAI
                     AHGVNYFDVAPVYVRGLSEQATGLALSRHSRDKYFIATKLSTHRPVPEWRTLEGSKGL
                     FEQSLKNLRVDYIDYYLIHGVGLGGMDDLRKRLYDNGVLDFLLKERKAGRIRNLGWSF
                     HGDVKVFDYLLSLDIPWDFVQIQLNYVDWKNASGWNVNAEYLYGELEKRNIPVVIMEP
                     LLGGRLSRLNALSLAKLKQMRPDDSPASWAFRYAGSPKGVLTVLSGMVYMEHLQENIR
                     TFSPLEPITEQENKALEEVTERMLHSDFVPCTECQYCMPCPYGLDIPGTFAHYNRCVN
                     DELVAKSSQDANYREARRAFLVGYDRKVPKLRQAGHCIGCDKCVPKCPQGIKIPEQMR
                     KIDQYVEQLKQETL"
     gene            complement(1670..3154)
                     /locus_tag="ACZPB4_16720"
     CDS             complement(1670..3154)
                     /locus_tag="ACZPB4_16720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011965991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HIR1099894.1"
                     /translation="MLRKIRLTLAVIIFTMTTLLFLDFTGVTHCWLGWIAKMQFLPAL
                     LAVNVGVVSVLLVLTLLFGRVYCSVICPLGVFQDVVSWIAGKRKKNRFSYSPAVSWLR
                     YGMLGIFIIAFLAGIGSLVALLDPYGAYGRIASNLFAPLYQWGNNLLAYWAERADSYV
                     FYSVDMWIKSVATFGVALVTFVVLFLLAWRNGRTYCNTICPVGTVLGFVARFSFLRPV
                     IDVEKCNGCGLCARNCKAACIDSKNHSIDYSRCVTCLDCIDKCKRGALTYVPRKRKTE
                     SEREADRPEENTRRNFLTFTGLLATSVLKAQSGVNADGGLADIADKLTPDRMTPIVPP
                     GALSLRNFTGHCTACQLCVSVCSNQVLRPSTDLKKFMQPEMSYERGYCRPECTKCSEV
                     CPTGAIQLITKADKSATQIGHAVWIKENCVVNTDEVNCGNCERHCPTKAIQMVAKDPN
                     DPKSLKVPVIDTELCIGCGACEYYCPSRPLSAIYVEGHERHRTV"
BASE COUNT         1022 a          880 c          613 g          848 t
ORIGIN      
        1 ggcgacagcc ccacccccaa ataccttcaa gaatttacgg cgattcatct cttgagggtt
       61 ctcattcttt ccacatgaac tcataactcg atcggttttt tatcctatta gtatatccaa
      121 cattagtcta tcattaacat tccttctatt atttcgacaa aaatagtaaa acaggtaata
      181 atagagaaca atccccgact aaaaagaata atcggggatt tatcacgaat aaagcaggta
      241 ttttaaataa gactataaag tctcttgctt caattgctcc acgtattgat cgatctttcg
      301 catttgctcc ggtatcttaa tgccttgcgg acatttcggt acgcatttat cgcatcctat
      361 acagtgtccg gcttgacgaa gtttaggaac cttacgatca taaccgacta agaacgcccg
      421 gcgagcctcc cgataattcg catcctgtga actcttcgca accagctcgt cattcacgca
      481 acggttataa tgagcgaacg ttcccggaat atccaagcca tacggacaag gcatacaata
      541 ctgacattcc gtacaaggta cgaaatccga atgtagcatc ctctccgtca cctcttccaa
      601 agccttattt tcttgttccg taatcggttc caaaggcgag aaggttcgga tgttctcttg
      661 taaatgctcc atatacacca taccactcag cacggtcagt actccttttg gagagcccgc
      721 ataccgaaaa gcccacgagg ccgggctgtc atccggacgc atctgtttca atttagccaa
      781 cgaaagggca ttcagccgag ataaacgccc gcctaaaaga ggctccatga taacgacggg
      841 aatattacgc ttctccaatt ccccatacaa atactccgca ttcacgttcc aaccagaagc
      901 atttttccaa tccacgtaat tcaactggat ctgaacgaag tcccaaggga tatccaagga
      961 taacaaataa tcgaagacct tgacgtctcc atgaaacgac cagcccaaat tgcggatacg
     1021 accggctttc cgctccttta acaagaaatc caagacaccg ttatcgtaaa ggcgcttcct
     1081 caaatcgtcc atgcccccca gacctacacc atgaatcaga taataatcga tataatccac
     1141 tcgcagattc tttagcgact gttcgaacaa gcccttggag ccctcaagag tacgccattc
     1201 cggtacagga cgatgggttg aaagcttcgt ggcgataaaa tatttatccc gggaatggcg
     1261 actaagagct agccctgttg cctgttcgga aagaccgcgc acgtaaaccg gtgccacatc
     1321 aaagtagttc acgccatgag caatcgcata atccaccaat gcattcaccg cttcttgatc
     1381 gatctcttcc cccgatccat ccgctttctg acgcaacggc cagcgcatac atccatatcc
     1441 taacaaggag accttatcgc ccgtatgcgg attcgtccgg tatgtcatct tatctgtcgg
     1501 gacttcaccc aaatagcttc cggtctgcga cacaccttgc cgcttaggat ctccaccaca
     1561 tccatataaa agccctgtcg aggcagcggc cgtaccggtg ctcaatactt ttaagaaatt
     1621 cctgcgatct atattattat tactcattac catacatttt ttgagattat taaaccgtac
     1681 gatgtctctc atgtccctca acatagattg cgcttaacgg acgagacgga caataatatt
     1741 cacatgcgcc acaaccgata caaagttccg tatcgataac cggtactttc aatgatttag
     1801 gatcattggg gtctttcgcc accatctgaa tagctttcgt cggacaatgc cgctcacagt
     1861 tgccacaatt tacctcatcg gtattcacca cacaattttc cttgatccat accgcatgtc
     1921 caatctgcgt ggcggatttg tccgctttcg taatcaattg gatcgcaccg gtcggacaaa
     1981 cctcggagca tttcgtacat tccggacgac aatatcctcg ctcatacgac atttccggtt
     2041 gcataaactt ctttagatct gtagaaggac gcaaaacttg attcgaacat accgagacac
     2101 agagttgaca agccgtacaa tgtccggtga agtttcgtaa actcaaagcc ccgggcggaa
     2161 ctatcggggt catacgatcc ggggttaact tatccgcaat atccgccaac cctccatccg
     2221 catttacccc cgactgggct ttcaataccg atgtcgccag caatcccgta aaggttaaga
     2281 aattacggcg ggtgttttct tcaggtcgat cagcctctct ctccgattct gtttttcgtt
     2341 tacgaggcac atatgtcaaa gctcctcttt tacatttatc gatgcagtcc aagcaagtaa
     2401 cgcaacgact ataatcaatc gaatgatttt tcgaatctat acaggcagcc ttgcaattac
     2461 gggcacataa gccacatccg ttgcatttct ctacatcgat caccggtctt aaaaaagaaa
     2521 aacgggcgac aaatcccaag accgtaccca ccggacagat cgtattacaa tacgtacgtc
     2581 cattacgcca agccaatagg aaaagaacca caaacgtaac gagcgctacc ccaaacgtag
     2641 ccacactttt tatccacata tctacagaat aaaagacata actatccgca cgctccgccc
     2701 aataagccaa gagattattt ccccattgat ataaaggagc aaaaagattc gaggctattc
     2761 gtccataggc tccatacgga tctaatagag ccaccagaga accgataccc gctaaaaaag
     2821 cgataataaa aattcctaac attccataac gtaaccatga gactgccggg gaataagaga
     2881 aacgattctt tttgcgtttt ccggctatcc aagaaacaac atcttgaaat acgcctaacg
     2941 gacaaataac cgaacaatag acacgtccaa agagtaaggt taataccaat aataccgata
     3001 caaccccaac attcaccgcc aataaggccg gcaggaattg catttttgct atccatccca
     3061 accagcaatg cgttaccccc gtaaagtcaa ggaacaaaag agtggtcata gtaaagataa
     3121 tgacagcgag tgttaatcta attttacgta acatataaga tcatttttct gtttacataa
     3181 ataatacgtt cgtttttatc acaaaaaaag caaattaaca taaacgatgt tttgaactca
     3241 agagcaaaaa gaatattcgg ggctttatca cgaaaaaaac ggatttttgt tgtatttttg
     3301 cgaattgtta tcaagaatga ttagacgaac aggcacatgg aaaaagaaga aaatccgata
     3361 tac
//
LOCUS       DBMDTB010000191         3333 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_6445_length_3333_cov_14.473700, whole genome shotgun sequence.
ACCESSION   DBMDTB010000191 DBMDTB010000000
VERSION     DBMDTB010000191.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 3333)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 3333)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3333
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_6445_length_3333_cov_14.473700"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..2513)
                     /gene="mutS"
                     /locus_tag="ACZPB4_16725"
     CDS             complement(<1..2513)
                     /gene="mutS"
                     /locus_tag="ACZPB4_16725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005782858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HIR1099895.1"
                     /translation="MKQYFDIKAKHPDAILLFRVGDFYEMYGEDAVIGAEILGIVQTK
                     RANGVGQHVEMAGFPHHALDSYLPKLVRAGKRVAICDQLEDPKLTKKLVKRGITELVT
                     PGVSINDNILNHKENNFLASIHFAKEVCGISFLDISTGEFMTAEGSIDYIDKLLNNFS
                     PKEVLIERGNKKRFEEAFGPRFFIFELDDWIFTTSAAEDRLLKHFETKNLKGFGVQHL
                     KLGIIASGAILYYLDQTQHTHISHITALSRIEEDRYVRLDKFTVRSLELVGTMNDEGT
                     SLLDVIDKTISPMGSRMLRRWILFPLKDVKPIQERQEVVDYFFREPETKELLDTQLEQ
                     IGDLERIISKVAVGRVSPREVVQLKVALRAIEPIKEACMASGEPSLCRIGEQLNACAL
                     IRDRIEKEINNDPPSLVNKGGIIAKGVNEELDDLRAIAYSGKDYLLKVQQREIELTGI
                     PSLKIAFNNVFGYYIEVRNTHKDKVPANWIRKQTLVNAERYITEELKEYEEKILGAEE
                     KILALETRLFNELVLALTEYIPPIQMNANLIGRIDCLLSFAKAAEANKYIRPVVSDSD
                     KIDIKGGRHPVIEKQLPLGEPYIANDVYLDDEKQQIIIITGPNMAGKSALLRQTALIT
                     LMAQIGCFVPAESAHIGIVDKIFTRVGASDNISVGESTFMVEMNEASDILNNMTSRSL
                     VLFDELGRGTSTYDGISIAWAIVEYIHEHPNAKAKTLFATHYHELNEMERAFKRIKNY
                     NVSVKEVGNKVIFLRKLIPGGSEHSFGIHVAKMAGMPKSIVKRSNEILKQLESENRQE
                     GIGGKPVKAIASAAEGYQLSFFQLDDPVLSQVRDEIKNL"
     gene            complement(2599..3255)
                     /gene="fsa"
                     /locus_tag="ACZPB4_16730"
     CDS             complement(2599..3255)
                     /gene="fsa"
                     /locus_tag="ACZPB4_16730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010538888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HIR1099896.1"
                     /translation="MKFFIDTANLDQIREANELGVLDGVTTNPSLMAKEGIRGVENQR
                     KHYLEICEIVGGDVSAEVIATDLEGMIKEGEELAALHPNIVVKVPCIEAGIKAIKYFT
                     RKGIRTNCTLVFSVGQALLAAKAGATYVSPFVGRLDDIASDGIELVRKIVEMYDYYDY
                     DTQVLAASIRSTQHIIQCVEAGADVATCPLSAIKGLLKHPLTDSGLATFLADYKKVNG
                     "
BASE COUNT          848 a          940 c          667 g          878 t
ORIGIN      
        1 tccaagttct tgatctcatc ccgtacttgg ctcaacaccg gatcatccaa ctggaagaaa
       61 ctcagctgat acccctcggc ggcagaggcg atcgctttta caggcttacc cccgatgcct
      121 tcctgacgat tctcggactc caactgcttc aagatctcat tcgaacgctt cacgatgctc
      181 ttgggcatac cggccatttt cgccacgtgg ataccaaagc tatgctcgct tcctcccggt
      241 atcaacttac gcaagaatat caccttattc cctacttcct tgaccgatac gttataattc
      301 ttgatccgct taaaggcacg ctccatctcg ttcagctcgt ggtaatgggt agcgaacagc
      361 gtcttcgcct tcgcgttagg gtgctcatga atatattcca cgatcgccca agcgatcgat
      421 atgccatcgt aggtactggt accccgccct aactcgtcga aaagcaccaa gctccgggaa
      481 gtcatattat ttaatatatc ggaggcctca ttcatctcta ccataaaagt agactcaccc
      541 accgagatat tatccgaggc acctacacgg gtaaatatct tatccacgat accgatatgg
      601 gcgctctcgg ccggaacaaa gcaaccgatt tgcgccatga gcgtgatcaa ggctgtctga
      661 cgcaataagg cggacttacc ggccatattc ggacccgtga taatgatgat ctgttgtttc
      721 tcgtcatcca gatagacatc attggcgata taaggttctc ccaagggcag ttgtttctcg
      781 attaccgggt ggcgacctcc ctttatgtcg atcttgtcgg aatcactcac gaccggacgg
      841 atatacttat tcgcctccgc agccttggcg aaagataaaa ggcaatcgat acgcccgatc
      901 aagttcgcgt tcatctggat aggcggaata tactccgtca aggccaatac cagctcattg
      961 aaaaggcggg tctccagagc aaggatcttt tcttccgccc ctaatatctt ctcctcgtat
     1021 tccttcaact cctcggtaat atagcgctcg gcgttcacca aggtctgttt acggatccaa
     1081 ttcgccggga ctttatcctt atgggtatta cgtacctcta tataatagcc gaagacgttg
     1141 ttgaaagcga tcttcaagct tgggataccc gtcaattcga tctcgcgctg ctgtaccttc
     1201 aacaaataat ccttgccgga ataagcgatg gcacgcaagt catccaattc ctcgttgaca
     1261 cccttcgcta taattcctcc cttattgacc aaagaagggg gatcgttatt aatctctttc
     1321 tcaatccggt cgcggatcaa ggcgcaagcg tttaattgct ccccgatccg gcataagctg
     1381 ggttccccgc tcgccataca tgcctccttg atcggctcga tcgcacgaag cgcgaccttt
     1441 agctgaacca cctcacgagg agatacacgg ccgacagcca ccttggagat aatacgctcc
     1501 aagtcgccga tctgctccaa ctgcgtatcc agcaactcct ttgtctccgg ttcacggaag
     1561 aaataatcca cgacctcttg gcgttcttgg atcggtttta catcctttag cgggaatagt
     1621 atccaccggc gaagcatacg agagcccatc ggcgagatcg tcttatcgat cacgtccaac
     1681 aagcttgttc cctcatcgtt catcgtaccc accagttcca agctgcgtac cgtaaactta
     1741 tccaagcgga cgtatcgatc ctcctcgata cgggataaag cggtgatatg ggaaatatgc
     1801 gtatgctggg tctggtccag ataatacaga atcgccccgg aagcgataat acctaatttc
     1861 aagtgttgta cgccaaaacc cttcaagttc ttcgtctcga aatgcttcaa caggcgatcc
     1921 tcggcggccg aggtcgtaaa gatccaatca tccagctcaa agataaagaa acgaggaccg
     1981 aaagcctcct cgaaacgttt cttgtttccc cgttcgatca acacttcctt cggggaaaaa
     2041 ttattgagta atttgtcgat atagtcaata gaaccctccg ccgtcatgaa ctcgccggta
     2101 gagatatcca agaaagagat accacatacc tccttggcga aatggataga ggccaagaaa
     2161 ttattctctt tatgattcag tatattatca ttgatggaaa caccgggagt caccaattcc
     2221 gtaattcccc gcttcaccaa tttcttagtc aatttaggat cttccagctg atcacaaata
     2281 gccacacgct taccggcccg caccaatttc ggcagataag aatccaaggc atgatgtgga
     2341 aatcccgcca tctcaacatg ctgccctacg ccattcgcac gtttggtctg tacgataccc
     2401 agtatttccg cgccaatcac ggcgtcctcg ccatacatct cgtaaaagtc tccaacccgg
     2461 aataaaagga tagcgtccgg atgtttcgct tttatatcga aatactgctt catcaaaggg
     2521 gtttccacaa cttttgccac gatagtaatc ttttaaatgc gtttacgaat taatccgcac
     2581 aaaggtacta ttttttttct atccgtttac tttcttataa tccgctagaa aagtagccag
     2641 cccactatcc gttaacgggt gtttcaataa gcctttaatg gcggacaaag gacaggtagc
     2701 cacatccgcc cccgcctcca cgcattggat gatatgctgg gtgctacgga tagaagccgc
     2761 caatacttgg gtatcataat cgtaataatc atacatttcc acgatcttac gtaccagctc
     2821 tatcccatcg ctggcgatgt catccaaacg cccgacgaac ggcgatacat acgtagcccc
     2881 ggccttagcc gccaataacg cctgaccgac agagaaaacc agcgtacaat tcgtacggat
     2941 gccttttctg gtgaaatatt ttatcgcttt aatccccgct tcgatacaag gtactttaac
     3001 gactatatta ggatgtaaag cggccaactc ctccccttct tttatcatgc cttctaagtc
     3061 ggtagcgatt acctcggcgc taacatcccc gcccacgatc tcgcaaattt ccaaatagtg
     3121 tttccgttga ttttccaccc cccggattcc ctctttcgcc attaaggacg gattagtcgt
     3181 cacgccatcc aatactccca attcattcgc ttcccggatc tggtccagat tcgccgtgtc
     3241 aataaaaaac ttcatagctt taaactttaa tgttacgtat ttgtataacc cttctgattc
     3301 gctattagtt ctaaatcaac cgtctcaatc ccc
//
LOCUS       DBMDTB010000192         3137 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_6940_length_3137_cov_9.838933, whole genome shotgun sequence.
ACCESSION   DBMDTB010000192 DBMDTB010000000
VERSION     DBMDTB010000192.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 3137)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 3137)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3137
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_6940_length_3137_cov_9.838933"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..864
                     /locus_tag="ACZPB4_16735"
     CDS             <1..864
                     /locus_tag="ACZPB4_16735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HIR1099897.1"
                     /translation="PNAEKPIVTEPADAVATLNSLVIEMEDRYRLLVNANVRNIKEYN
                     AKFIERRLNPQKGHRFLPYIVAVVDEFADLIAVAGREIELPISRIAAKARAVGIHMIL
                     ATQRPDTKVITGTIKSNFPSRIAFKVASMIDSRTILDAPGANRLIGRGDMLIVVAGQE
                     PVRVQCAFVDTPEVEDIVDYIGEQAGFQTAYLLPDYVPEGGEASTSGAVDLSDRDPLF
                     DEAARLIVIQQQGSTSLIQRKFAIGYNRAGRLMDQLEAAGIVGPFEGSKARQVLVQDE
                     YSLEQVLNALK"
     gene            867..1541
                     /gene="lolA1"
                     /locus_tag="ACZPB4_16740"
     CDS             867..1541
                     /gene="lolA1"
                     /locus_tag="ACZPB4_16740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011965993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0042597 - periplasmic space [Evidence
                     IEA];
                     GO_process: GO:0042953 - lipoprotein transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipoprotein periplasmic chaperone
                     LolA1"
                     /protein_id="HIR1099898.1"
                     /translation="MRREYKVRVWRCIAFVGLFLCFLLGLGVGAYAQNANDILGKAAA
                     AYENSNGISASFTMFTRSAGQNAGESFEGTIQMKGDKFTLVTPEALTWFNGTTQWTYV
                     ERNDEVNVTNPTGEELQFTNPALLLNSYKKGFTAAYKGESTAPNGKAAYDVELTPKKK
                     GDIVKVELQIEKYSNFPARITVTSKNGVSSTIQISQLKTGINQPDRFFVFNEGDYPDV
                     EVIDLR"
     gene            1579..2532
                     /gene="trxB"
                     /locus_tag="ACZPB4_16745"
     CDS             1579..2532
                     /gene="trxB"
                     /locus_tag="ACZPB4_16745"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HIR1099899.1"
                     /translation="MSDSVNEKVRCLIIGSGPAGYTAAIYASRANLSPVLYEGIQPGG
                     QLTTTTEVENFPGYPDGITGPELMEDLKKQAVRFGADIRFGIATAADLGEAPYKITID
                     GEKVIETETLIIATGASAKYLGLPDEHKYAGMGVSACATCDGFFYRKKTVAVVGGGDT
                     ACEEAIYLAGLAKQVYLIVRKPYLRASKVMQERVFKTPNITVLFEHNTLGLFGENGVE
                     GAHLVKRMGEPDEEKVDIAIDGFFLAIGHKPNSDIFKPWVDTDEVGYIVTVPGTPRTK
                     VPGVFAAGDVADPHYRQAITAAGSGCKAAIEAERYLSEIGK"
     gene            2605..>3137
                     /locus_tag="ACZPB4_16750"
     CDS             2605..>3137
                     /locus_tag="ACZPB4_16750"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008771634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008081 - phosphoric diester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HIR1099900.1"
                     /translation="MNLKSTLLLLLCLMMAGMVAAKDNTKVIAHRGYWKTEGSAQNSI
                     RSLERASEIGAYGSEFDVHLTADNVLVVYHDNDIQGKHIQSCTYDELKDLQLSNGEKL
                     PTLEQYLKRAKKLKNIRLIFELKSHDTPERNRDAARLSVQMVKRMKLAKRTDYISFNM
                     DACKEFIRLCPKSEVSYL"
BASE COUNT          834 a          586 c          864 g          853 t
ORIGIN      
        1 ccgaatgcgg agaagccgat cgttacggag ccagctgacg ctgtcgctac attgaactcg
       61 ttggtgatcg agatggaaga ccggtaccgt ttactggtga atgcgaatgt tcgtaatata
      121 aaggaataca acgctaagtt tatcgaacgg cggttgaacc cgcagaaggg acatcgcttc
      181 ttaccctata tcgtggcagt ggtggatgag tttgccgact tgatcgcagt ggccggacgt
      241 gagatcgagt tgcctatctc tcgtattgcg gcgaaggccc gtgcggtagg tatccatatg
      301 atcttggcta cgcaacgccc ggatacaaag gtgattaccg gtacgatcaa gagtaacttt
      361 ccgagccgta ttgcctttaa ggttgcttct atgatcgatt cacgtacgat tctggatgct
      421 ccgggtgcta accgtttgat cggacggggt gatatgttga ttgttgtagc gggacaagag
      481 ccggttcgtg tgcaatgcgc ttttgtagat acgcccgagg tggaggatat cgtggattat
      541 atcggtgagc aggctggctt ccaaaccgct tatctgcttc cggactatgt accggaaggg
      601 ggagaggcat cgacttcggg agctgtcgat ttatcagatc gagacccctt atttgatgag
      661 gcggctcgct tgatcgtgat tcagcaacaa ggttcaactt ctttgatcca gcgtaaattc
      721 gctatcggtt ataatcgtgc cggacgtttg atggatcaat tggaggctgc cggtattgtt
      781 ggcccgtttg agggaagtaa ggcccgtcaa gtattggtgc aagatgagta ttcgttggag
      841 caagtattaa atgctttgaa ataaatatga gaagagaata taaagtaaga gtgtggcggt
      901 gtatcgcgtt tgtcggatta ttcttgtgtt tcctgctggg actaggagtg ggggcgtatg
      961 cccagaatgc gaatgatatt ttggggaagg cggccgctgc ttatgagaat tcaaatggga
     1021 taagtgcttc ttttacgatg tttacccgtt ctgccggtca gaatgcggga gagagttttg
     1081 agggaaccat ccagatgaaa ggtgataagt ttacattagt tacgccggag gcgcttactt
     1141 ggtttaatgg tacgacgcaa tggacgtatg tggaacggaa cgatgaggtg aacgtgacga
     1201 atcctacggg agaggagttg caatttacaa atcccgctct tttattaaat agttataaga
     1261 agggattcac ggcggcttat aaaggcgaga gtacggcacc gaacggaaaa gccgcttacg
     1321 atgtggaatt gacaccgaag aaaaaagggg atatcgtgaa agtggagttg caaatcgaga
     1381 aatattcaaa tttcccggct cgtatcacgg ttacttctaa aaacggcgtt agcagtacga
     1441 tccagatcag ccaattgaaa acaggtataa accaaccaga tcgttttttt gtttttaacg
     1501 aaggggatta tccggacgta gaggtgatag accttcgata atagagaatt gaaaattgat
     1561 aattaatact tagatactat gagcgattca gtgaatgaga aagtacgttg ccttattata
     1621 ggctcgggtc cagcaggtta tacggcagcg atttatgctt cccgtgcaaa tttatctccg
     1681 gtgctttatg aaggaataca gccgggggga caattaacga caactacgga ggtggagaat
     1741 ttcccgggat atccggacgg tataaccggt cctgagttaa tggaagattt aaaaaaacaa
     1801 gccgtccgtt ttggtgcgga tatccgtttc ggtatcgcta ccgccgctga tttgggtgag
     1861 gctccttata aaattacgat tgatggcgag aaagtgatcg agacggagac tttgattatc
     1921 gctacgggtg cttccgcgaa gtatctgggt cttccggatg aacataagta tgcgggtatg
     1981 ggtgtatccg cttgtgctac ttgcgatggt ttcttctatc gtaaaaagac ggtagcggta
     2041 gtgggtggtg gagatacggc ctgtgaggaa gcgatttact tggctggttt ggcgaagcag
     2101 gtttacttga tcgtgcgtaa accctatttg cgtgcttcaa aagtaatgca agaacgtgtc
     2161 ttcaaaactc cgaatatcac ggtacttttc gagcataata ccttaggttt gtttggagag
     2221 aatggcgtgg agggtgctca tttggtaaaa cgtatgggag agccggatga ggagaaagtg
     2281 gatatcgcca tcgatggttt cttcttggcg attggtcata aacccaattc ggacatcttc
     2341 aagccatggg tagatacgga tgaggttggt tatatcgtga cggttccggg aactccccgc
     2401 acgaaagttc cgggtgtatt tgccgccgga gatgtcgctg atccccatta tcgtcaagct
     2461 attaccgctg cgggaagtgg ttgtaaggca gctattgagg ccgaacgtta tttatcagag
     2521 atcggaaaat aatccgtggg aggagggtgt gccatatcat aaattatgac acaccctcct
     2581 cttgccttga aatacaagtt taccatgaat ttaaaatcta ctcttctttt gctactttgc
     2641 ctgatgatgg caggaatggt agcggcaaag gataatacga aagtgatagc ccatcggggg
     2701 tattggaaaa cggagggctc tgcccagaac tctatccgct ctttggaacg tgctagcgaa
     2761 attggtgcct atggctcgga attcgacgtg catcttacag cagacaatgt gttggttgtc
     2821 taccacgata atgatatcca aggaaaacat atccaatctt gtacatacga tgaattgaag
     2881 gatctacaat tgagtaacgg cgaaaagctc cctactttgg aacaatattt gaaacgtgcg
     2941 aagaaattga agaatatccg gttaatattt gaattgaaat cccatgatac cccggaacgt
     3001 aatcgagatg cggcaaggtt atctgtgcaa atggtaaagc gtatgaaatt agcgaaacgt
     3061 acggattaca tatcttttaa tatggatgct tgtaaagaat ttatccgtct atgtccgaaa
     3121 tctgaggttt cttatct
//
LOCUS       DBMDTB010000193         3064 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_7141_length_3064_cov_13.160310, whole genome shotgun sequence.
ACCESSION   DBMDTB010000193 DBMDTB010000000
VERSION     DBMDTB010000193.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 3064)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 3064)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3064
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_7141_length_3064_cov_13.160310"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..1640)
                     /locus_tag="ACZPB4_16755"
     CDS             complement(<1..1640)
                     /locus_tag="ACZPB4_16755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase family protein"
                     /protein_id="HIR1099901.1"
                     /translation="MNTTHHTHSCVHDTVSSVGANNFGMNDRIKRLRRQTFEAQPSLS
                     IERALIETRFYQENYGKYPIPILRALNFLEICKRKTIYIGEDELIVGERGPRPKAVPT
                     FPELTCHSVEDLHILNTRELQRYTISQEDIDTYEREVIPYWKGRTQRERIFSHVPKEW
                     KEAYEVGMFTEFMEQRAPGHTALDGKVYQYGLLDLKKRIEGELSALDFMNDPEATDKQ
                     EELTAMSISCDAAILLAERHADLADEMSLTEKDPRRAAELRKIAEVCRRVPAHAPRTY
                     WEAIQMYWFVHLGTITELNGWDAMNPGHFDQHLAPFYEKEIAAGTLTRDEAKELMSCF
                     FIKVNNHTAPPKVGITAKESGTYNDFTNLNIGGIRADGSDGVSEVSYIMLETIEELHI
                     LQPGSAIHVSARTPERFLRAGCKVIRQGHGYPSVFNPDVYVQELMRQGKSLRDAREGG
                     CSGCIEVGAFGKEAYVLTGYLNVPKILEVTLHNGVDPVSGRKVGLETGDPRGFRTYEE
                     LYAAFMRQIHYFVDMKVRVSNYIDRMFAKYAPATFLSL"
     gene            1986..>3064
                     /locus_tag="ACZPB4_16760"
     CDS             1986..>3064
                     /locus_tag="ACZPB4_16760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1099902.1"
                     /translation="MQSTFKNLLYVLRHYKLATVTNLLGLSFAFLLFMLISIHVGHEY
                     SFDASLLNRERIFQLENKRDDGIWEANFARPQLERFIAASPYIEAAAITNNLVYSSVR
                     FGISASEGPDARSYMEQVERITPGYTKVFGFELVAGDTDCLKRPEGTLIPESMARKLF
                     GEENPIGKPVYLSEFAGAEGSIIYGLSFEPAYIVGGVFRDFPENTRVKNALYIPIMEK
                     EMMENWHTGLYYCYLLMSTPESASVTTETYMADSRAFLKSFTIEDMRLRPLSDLYFGQ
                     PVRADAAPIGNKLRTNMLFFIAILIIGIALVNYINLSIALAPIRTKSITIQKVLGSSD
                     ATLRKYLVLESLGISVVAFFLALLFL"
BASE COUNT          699 a          813 c          806 g          746 t
ORIGIN      
        1 aacagggaga ggaacgtggc gggggcgtac ttggcgaaca tgcggtcgat atagttgctg
       61 acccgcacct tcatgtccac gaaataatgg atctggcgca tgaatgccgc gtaaagctcc
      121 tcatacgtcc ggaaaccacg gggatcgccg gtctccagac cgaccttgcg accgcttacc
      181 ggatctacgc cgttatgcag cgtcacctcc aatatcttcg gcacgttcag ataaccggtc
      241 aacacgtacg cctccttccc gaaagcgccc acctcgatgc aaccgctgca acctccctcg
      301 cgggcgtcac gcagcgactt gccttgccgc atcaactcct gcacgtacac atccgggttg
      361 aataccgacg ggtagccatg gccttggcgg atcaccttgc acccggcacg aaggaaacgc
      421 tccggcgtac gggcactgac gtggatggcg ctgccgggct ggaggatatg cagctcctcg
      481 atcgtctcca acatgatata ggagacctcg cttacgccat cgctaccgtc cgcccggatg
      541 ccgccgatgt tcaggttcgt gaaatcgtta taggttccgc tctccttcgc cgtgataccc
      601 actttcggcg gggcggtatg attgtttacc ttgatgaaga agcaagacat caactctttc
      661 gcctcgtcac gggtcaaggt tccggcggcg atttctttct cgtagaaagg cgccagatgc
      721 tggtcgaaat gaccggggtt catggcatcc caaccattca gctccgtgat cgtaccgagg
      781 tggacaaacc agtacatctg gatcgcttcc caataggtac ggggagcgtg ggcgggaacc
      841 cggcggcata cctcggcgat cttcctcagc tcggcggcac ggcggggatc tttctcggtg
      901 agagacatct cgtcagccaa gtccgcgtgt cgctcggcca gcaggatagc ggcgtcgcag
      961 gagatagaca tggccgtcag ttcctcctgc ttgtccgtgg cctcggggtc gttcatgaaa
     1021 tccaaggcgc ttagttcccc ctcgatacgt ttcttcaagt ccagcaggcc atattggtag
     1081 accttgccgt ccaaagcggt atgcccgggg gcacgttgct ccatgaactc ggtgaacata
     1141 cccacctcgt acgcctcttt ccattccttg gggacgtggc tgaagatgcg ttcccgctgg
     1201 gtacggcctt tccagtacgg gatcacctcc cgctcgtagg tatcgatatc ttcttgactg
     1261 atggtgtaac gttgcagctc ccgggtattc aatatatgca agtcctccac gctatggcag
     1321 gtaagttccg ggaaggtagg cacggctttg gggcggggcc cccgctcgcc gacgatcaac
     1381 tcgtcctcgc cgatatagat cgtcttccgc ttgcagatct caaggaagtt cagggcacgc
     1441 aggataggga tcggatactt cccgtaattc tcctgataga aacgggtctc gatcaaggcc
     1501 cgctcgatgg agagggaagg ttgggcctcg aaggtctgcc ggcgcagacg tttgatacgg
     1561 tcgttcatcc cgaaattgtt cgctcctacg gaagagacgg tatcatgtac gcatgaatgt
     1621 gtgtgatggg ttgtattcat aaaattatat gttttatcgt agaggtagga tctatccgcc
     1681 ctcatcaagg ttatttttta ttgttacaca ggacgggcat ccccgccccc atgagtttat
     1741 atagggagag tatctgctag agataaaaca tcaggcagtt gaaaagcatc cgatagcctt
     1801 tgtgtaacat agcgcttgtt tctttttgaa gtatgatggc aaaaataagg aaattattga
     1861 taatatcaca attcatcaac agaaagtaac cgtttgtcaa aaaaataaca caggaacgta
     1921 aataaaggaa tagctttgct ttgtatttcc agatcaaagg gtttaaaatt aaaagaactt
     1981 ataccatgca aagtacattc aagaacctgc tttatgtctt gagacattat aaattagcga
     2041 cggtcactaa tcttttagga cttagcttcg ctttcctgtt attcatgcta ataagcatac
     2101 atgtcggtca tgaatatagc ttcgacgctt ccctcttgaa cagggaaagg atttttcagt
     2161 tagaaaacaa gcgggatgac gggatatggg aggctaattt cgcacgtcca caactcgagc
     2221 gtttcatcgc cgcctcccct tatatagaag cggccgctat cacaaacaac cttgtttact
     2281 cctccgtacg ttttgggata tcagccagtg aaggacccga cgcacggagc tatatggagc
     2341 aggtggaacg gatcaccccg ggatatacca aggtctttgg cttcgagctg gtggccggcg
     2401 atacggattg cctgaaacgt ccggaaggga cgctgatccc ggagagcatg gcccggaaac
     2461 tcttcggcga ggaaaatcct atcgggaagc cggtttatct gtcggagttc gccggggccg
     2521 aaggctcgat tatatatggg cttagttttg agccggcata tatcgtggga ggcgtctttc
     2581 gcgatttccc ggaaaacacc cgggtgaaga atgccctgta tatcccgatc atggagaaag
     2641 agatgatgga aaactggcat accggccttt actattgtta tctgctgatg tcgacgccgg
     2701 aatccgcctc tgtcactacc gagacctata tggccgatag ccgggctttc ctgaaaagtt
     2761 tcacgatcga ggatatgcgc ctccggccct tgtcagatct ctatttcggc cagccggtcc
     2821 gagcggacgc cgctcccatc ggtaataagc tacggacgaa tatgttattc tttatcgcca
     2881 tcctgatcat aggtatcgcc ttggtcaatt atatcaacct gtcgatagcc ttggcgccga
     2941 tacgcaccaa gtcgatcacc atccagaaag tgctgggaag ctcggacgcc acgctacgga
     3001 agtatctggt cttggagtcc ttgggaatct cggttgtcgc cttcttcctc gccttgcttt
     3061 tcct
//
LOCUS       DBMDTB010000194         3054 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_7174_length_3054_cov_10.402980, whole genome shotgun sequence.
ACCESSION   DBMDTB010000194 DBMDTB010000000
VERSION     DBMDTB010000194.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 3054)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 3054)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3054
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_7174_length_3054_cov_10.402980"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..511
                     /locus_tag="ACZPB4_16765"
     CDS             <1..511
                     /locus_tag="ACZPB4_16765"
                     /EC_number="2.7.1.130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009029 - lipid-A 4'-kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="tetraacyldisaccharide 4'-kinase"
                     /protein_id="HIR1099903.1"
                     /translation="IQPIDFRIIEEDIHLSAYQELYFSRILYGELEPVFSGKAPRRTL
                     KGLASTTEVLLVSGIASPAPLEKEIHKYTEHVTSLVFPDHHAFDRHDIQKIQTAFKRL
                     TSTSKLIIITEKDAARLRDLPSLPMEWFSHLYCLPITVGFCMDREKQFQELIVKHIDT
                     RIKNHPILR"
     gene            519..1547
                     /gene="thiL"
                     /locus_tag="ACZPB4_16770"
     CDS             519..1547
                     /gene="thiL"
                     /locus_tag="ACZPB4_16770"
                     /EC_number="2.7.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009030 - thiamine-phosphate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-phosphate kinase"
                     /protein_id="HIR1099904.1"
                     /translation="MSNRTEISTLGEFGLIRHLTDKIELKNPSTLKGVGDDAAVLDYT
                     DKQVLVTTDLLLEGIHFDLMYVPLKHLGYKSAVVNFSDIYAMNGRPKQITVSLGISKR
                     FCVEDLEEFYEGIKLACDIYDVDLVGGDTSASRTGLAISITCLGEGEKGKVVYRNGAK
                     ETDLICVSGDLGAAYMGLQLLEREKSIFNGEKDFTPDFSGKEYLLERQLKPEARKDIV
                     EVLDQAGIVPTSMMDISDGLSSELLHISKESNVGCRVYEDRIPIDYQTAAMAEQFNMN
                     LITAALNGGEDYELLFTVPLADHDKVSEMKGIKVIGHITKPELGNYLVGRDGGEVELK
                     AQGWNSLN"
     gene            complement(1624..2739)
                     /locus_tag="ACZPB4_16775"
     CDS             complement(1624..2739)
                     /locus_tag="ACZPB4_16775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012056233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4852 domain-containing protein"
                     /protein_id="HIR1099905.1"
                     /translation="MKKVIWSIVLSWVCLAFAAGIGTRDAVSACDGKVYKKGDKIMFG
                     VPKVSGYLFVRTLTKDGKISTMPKENLASQEAVIVDIPDYDKKLFESMGVYSEVETHP
                     LVVVELDGRRLCININDALSQGNIVSEYFKSEVEGVVDLTSDLLFVYALKLNNVAVDD
                     DVIVRYMAHCDKNLVEKNQADPFTMADLKKEYAAKLEKALGDVDFSKVFRIESQSEML
                     QYDMDKQIFPLKGLWCPQIKTDQPDALAKIGFCKWDDCVFRFVNIPEFMNVSCETARA
                     KGFYDMRKVGKVPTYNKPLATSYTYIRFLDKKVQLPEKKNKVYHNGDIKSMSLADLYG
                     KMAIEAQIIKMDVYHLPFLKISDFELFYNYLGSIEVK"
     gene            2955..3030
                     /locus_tag="ACZPB4_16780"
     tRNA            2955..3030
                     /locus_tag="ACZPB4_16780"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2988..2990,aa:Phe,seq:gaa)
BASE COUNT          927 a          721 c          554 g          852 t
ORIGIN      
        1 tatacaacct atagacttcc ggatcataga ggaggatata catctctcag cttatcaaga
       61 gctctatttc agccgtattc tttacgggga gctggaaccc gtcttttccg gtaaagcccc
      121 cagacgcaca ttaaaagggc tggcctctac tacagaggtt ttattggtat ccggtatcgc
      181 atccccggca cctctcgaaa aagagatcca taaatatacg gagcatgtca cctctttggt
      241 ctttccggat catcacgcct tcgatcggca tgacatccag aaaatacaaa cggctttcaa
      301 gcggttgact tctacaagta aattgataat catcacggag aaagatgccg cccgactccg
      361 tgaccttcct tcgcttccca tggaatggtt ttctcattta tattgtttgc ctattacggt
      421 gggtttctgt atggatcggg aaaaacaatt tcaagaatta atagttaaac atattgatac
      481 aagaataaag aatcatccta tattacgtta acaatcttat gagcaataga acagaaatat
      541 cgactttggg agagttcggg ttaatccgcc atctcaccga taaaatagaa cttaaaaatc
      601 cgagtacgtt gaaaggtgtt ggtgacgacg cagccgtact ggattacaca gacaagcaag
      661 tattggttac gacagacctt ttgctggaag gtattcattt cgatttgatg tatgtgccgt
      721 tgaaacatct cggctataaa tccgcagtcg taaacttctc cgatatttac gccatgaacg
      781 gccgcccgaa acagattacg gtatcattgg gtatttccaa acgtttctgt gtagaagatc
      841 tcgaagaatt ctacgagggc attaaactcg cttgtgatat ctatgacgta gatctcgttg
      901 gtggcgacac ttccgcctca cgcacagggt tagcgatcag catcacttgc ctaggcgagg
      961 gagaaaaagg caaagttgtc tatcgaaacg gagccaagga gaccgatctt atttgcgtgt
     1021 ccggcgattt aggggccgcc tacatgggtc tccaattact ggaacgggag aaaagcatat
     1081 ttaatgggga gaaagatttc acgcccgatt tctctggtaa agaatatttg ttggaacgcc
     1141 aattaaaacc ggaagcccgc aaagacattg tcgaagttct tgatcaagct ggaatcgttc
     1201 cgacctccat gatggatatc tccgacggcc tctcttcgga gttgcttcat atatctaaag
     1261 aaagtaatgt aggctgccga gtttacgaag atcgtattcc tatcgattac caaaccgcag
     1321 ccatggcaga gcagtttaac atgaatctga taactgcggc attgaatgga ggtgaggatt
     1381 atgaactctt attcactgtt cctttagcag atcatgataa ggtgtcggaa atgaaaggta
     1441 ttaaggtgat cggtcatata acaaagccag agttaggcaa ttatcttgtc ggtcgtgacg
     1501 gaggtgaagt cgagcttaag gcgcaaggtt ggaactcact aaactaaaaa gaaatatccg
     1561 ctctgaattc acgaatgcaa agcggtccat ctcattttta ttgggggacg gaccgttttc
     1621 ctattatttc acttcaatgg atcctaaata attatagaag agttcaaaat cacttatctt
     1681 caagaaaggt aagtgataaa catccatctt tataatttga gcctctatag ccattttccc
     1741 atacaaatca gccaaagaca tactctttat atcaccgtta tgatagacct tattcttttt
     1801 ctcgggaagc tgtaccttct tatccaagaa acggatataa gtataagagg tagccagcgg
     1861 cttattatag gtaggcactt ttccgacttt cctcatatca taaaaccctt tcgcacgagc
     1921 cgtctcacaa gagacattca tgaactctgg tatattcaca aatcgaaaga cacaatcatc
     1981 ccatttacaa aagccaatct tagccaacgc atccggctgg tctgtcttaa tttgtgggca
     2041 ccacaaccct tttaatggaa agatctgctt atccatatca tattgtaaca tctccgactg
     2101 actctcaata cgaaacacct tactaaaatc aacgtcccct aacgcctttt ccaatttagc
     2161 ggcatattct ttcttaagat ccgccatagt aaatggatcc gcttgatttt tctctaccag
     2221 attcttgtca caatgagcca tataccttac tatcacatcg tcatcaacag ccacattatt
     2281 taatttaagc gcataaacaa ataagagatc ggacgttaaa tcgaccacac cctcaacttc
     2341 gcttttaaaa tattccgaaa caatattccc ttgactaagc gcatcattaa tatttataca
     2401 aagacgccgt ccatccagct ctaccacgac aagaggatgc gtttctacct cagaataaac
     2461 gcccatactc tcaaagagtt tcttatcgta atccggaata tcaacgatca ccgcctcttg
     2521 actagctaga ttctcttttg gcatcgtaga tatcttccca tcctttgtta acgtcctaac
     2581 aaacaaatat ccggaaacct tagggacacc aaacataatc ttatcccctt ttttatacac
     2641 tttcccatca caggcagaca ccgcatcacg agttcctatc ccagcagcaa atgccaaaca
     2701 tacccaactt aaaacaatac tccaaattac tttcttcata tctatagctt attaatcatt
     2761 ctctacccgc ttccaaaaat aagtaaaaat ccatatttat ctacacgctc cccctattta
     2821 ccctgcttat agcagctaat tccacctcta ccctcaaata ttttcaaaaa atccaccgcc
     2881 acctattgca tatatcaaaa aagtccgtat ctttgcaccc gtaatcgaaa caacgatata
     2941 caaaacgaca tgatggtgcc atagctcagt tggtagagca aaggactgaa aatccttgtg
     3001 tccccggttc gattcctggt ggcaccacca aagaaagtac ataaatgctt ttca
//
LOCUS       DBMDTB010000195         3037 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_7220_length_3037_cov_13.361035, whole genome shotgun sequence.
ACCESSION   DBMDTB010000195 DBMDTB010000000
VERSION     DBMDTB010000195.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 3037)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 3037)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3037
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_7220_length_3037_cov_13.361035"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..729
                     /locus_tag="ACZPB4_16785"
     CDS             <1..729
                     /locus_tag="ACZPB4_16785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HIR1099906.1"
                     /translation="SDREMENLRWVARSYSDELPVYVPEAGYLRKGDRIRITDGRFKG
                     VEASVVIQPGVGEREVMVCVDNWMWVPLLRVQPGEYEVISLAEEGKHVYTRLDNSRIQ
                     NGLHEALGRHWGDGGVTAIDRELATETLRAYGELQLDSAVMRCKLYSLLLPAYTILGD
                     EERQKSLIGTIVSFLPLIRAEQSLALLLLTLYGCTDSSIYYYRAHELIDPWSRESSPK
                     KSKLSLIRRLADYDRWLKHVGIEN"
     gene            741..1121
                     /locus_tag="ACZPB4_16790"
     CDS             741..1121
                     /locus_tag="ACZPB4_16790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099907.1"
                     /translation="MPSLPSGIRLVTLLNEHLNEIMDRERMNRTSIHLYCTGPYWVAF
                     ERSAYQLCLTFPDSEITPLRLFAYPFPIVMVSVTDRSLRSYARKHILRRDETDYVVLT
                     VPESSLTDYRRWHAGEVEGLPQLT"
     gene            1138..>3037
                     /locus_tag="ACZPB4_16795"
     CDS             1138..>3037
                     /locus_tag="ACZPB4_16795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HIR1099908.1"
                     /translation="MMNLFSKLSTWYFSRKALPYWSIILLDCLVILFSGLLVYALNNG
                     IFATMGIFWHLSLTWGVCLVPYLVGFRLFRTYSGIIRYSSFVDLQRVGFAVLFGVVCV
                     VTFQEFTDFSPYLVYIRKRDLVLSSLLAMSLMWAMRVFVKYFYVTTFRQSKAERAFIF
                     GVKQGGISLAKSIQNQDPAQYVLAGFVSEAGNMQNRILMGVRVYPFDEELIDAMRRER
                     ATILFVSPLKSDSIREQPDMVARLAEAGIKIYVTPAAQEWDGRSDLTHTQLRKVEIED
                     LLPREKIEIDMEAVGRLLRGQRILITGAAGSIGGEMVRQIASFAPDRLILVDQAETPL
                     HDIRLMMARDWRDINAYTLVADIANKSRMEEIFSEHRPAYVFHAAAYKHVPMMEDNPC
                     ESVGNNVGGTRVIADLAVKYGTRKFVMISTDKAVNPTNVMGCSKRICEIYVQSLDKAI
                     KEGHVEGVTQFVTTRFGNVLGSNGSVIPLFREQIAKGGPVTVTHPDIIRFFMLIPEAC
                     RLVLEAGTMGNGGEIFVFDMGKPVRIIDLAKRMIQLSGAKNVEVRFTGLRAGEKLYEE
                     VLNDEEITLPTFHPKIKIAKVREYDYDTVCQDIDELVGLGRSRDDMAIVGKMKAIVPE
                     FKSRHSKYE"
BASE COUNT          625 a          716 c          927 g          769 t
ORIGIN      
        1 tccgatcgtg agatggaaaa cttgcgttgg gtggcccgtt cttactcgga tgagcttccg
       61 gtgtatgtgc cggaagcggg ttatttgcgt aaaggtgacc ggatacgcat tacggatggt
      121 cgttttaaag gtgttgaggc aagtgtagta atacagcccg gtgttggcga gcgggaggta
      181 atggtatgcg tggacaactg gatgtgggtt cctttattgc gtgttcagcc gggcgagtat
      241 gaggtgatca gcttggccga ggaaggcaag catgtatata cccgtttgga caattcccgg
      301 atacaaaatg gtcttcatga ggcgttgggc cgtcattggg gggatggtgg cgttacggct
      361 atagaccgtg agctggcgac cgagaccttg cgtgcctatg gagagttaca gttggattct
      421 gccgtgatgc ggtgcaagct ctattccctc ttgttgcccg cctatacgat actaggggac
      481 gaggagcggc aaaagtcgtt gatcggaacg atcgtctcgt tcttaccctt gatccgtgcg
      541 gagcagtcgt tggcattatt actacttacg ctttatggtt gtacggatag cagtatctat
      601 tattatcgtg cgcacgagtt gattgatccg tggagtcggg aatcctcccc gaagaagagt
      661 aaattatcct tgatccgtcg gttagccgac tacgaccgct ggctaaaaca cgtgggtatt
      721 gaaaattaaa aattcaaaac atgccttctc ttccttctgg catacgcttg gttacgttac
      781 taaacgagca tctgaacgag atcatggatc gtgagcgcat gaaccgtacc tcgatccatt
      841 tatattgtac gggtccttat tgggtggctt tcgagcgttc tgcctatcag ttgtgtctca
      901 ccttcccgga tagcgagatc acgccgctgc gcctgttcgc ctacccgttc ccgatcgtga
      961 tggtgtccgt gacggatcgc tcgttgcgtt cgtacgcccg taaacatatt ttgaggcggg
     1021 acgagacgga ttacgtggtg ctgaccgtcc ccgaatcctc cttgactgac taccgaagat
     1081 ggcatgccgg tgaggtggag ggcttgcccc agctgacatg aaccaaaaat tttattcatg
     1141 atgaaccttt tttctaaact ctcaacgtgg tatttctcaa ggaaagcgtt gccgtattgg
     1201 agcattatcc tgttggattg cttggtgatc ctgttttcag gcttgctggt atatgccttg
     1261 aataacggga tcttcgccac gatgggcatc ttttggcacc tgtcgctcac gtggggtgtt
     1321 tgcctagtgc cttatctggt gggctttagg ctgttccgta cgtattcggg catcattcgt
     1381 tactcttcct tcgtggattt gcaacgggtg ggcttcgccg tgctgttcgg tgtggtttgc
     1441 gtggtgacct tccaagagtt tacggatttt tcgccttact tggtgtatat ccgtaaacga
     1501 gaccttgtgc tatcctccct gctggcgatg agcttgatgt gggcgatgcg tgtgttcgtg
     1561 aagtatttct acgtgacgac ctttcgccag tcgaaggctg agcgtgcctt tatcttcggc
     1621 gtgaagcagg gcggtatcag tttggcgaag agcatccaga accaagatcc cgcacagtac
     1681 gtgctggcag gcttcgtctc ggaggccggg aacatgcaga atcgtatatt gatgggagtg
     1741 cgtgtgtacc ctttcgatga ggagctgatc gatgcgatgc gccgggagcg ggcgacgatc
     1801 cttttcgtct cccccttgaa gagcgactcc atccgggaac agccggatat ggtggcccgt
     1861 ttggcggagg cggggatcaa gatctacgtg accccggcgg cgcaagaatg ggatggcagg
     1921 agcgatttga cgcatacaca actccggaag gttgagatcg aggatctgct tccccgggaa
     1981 aagatagaga tagacatgga ggcggtgggc cgcttgcttc gtggtcaacg catcctgata
     2041 acgggagccg ccggcagcat cggtggcgag atggtgcgcc agatcgcctc gttcgctccg
     2101 gatcgcttga tcttggtaga tcaggcggag actcccttgc acgatatccg cttgatgatg
     2161 gcgagggatt ggcgggatat caacgcctat accttggtgg cggacatcgc taacaagtct
     2221 cgcatggagg agatcttctc ggagcatcgc cccgcctacg tgttccatgc ggcggcttat
     2281 aagcacgttc cgatgatgga ggataatcct tgcgagagtg tgggtaacaa cgtgggcggt
     2341 acccgtgtga tcgccgactt ggccgtgaag tatggcacga ggaagttcgt gatgatctcc
     2401 acggacaagg cggtgaatcc cacgaacgtg atgggttgct cgaaacgtat ctgcgagatt
     2461 tacgtgcaga gcctcgacaa agcgatcaag gagggccatg tggaaggcgt gacgcagttc
     2521 gttacgaccc gcttcggcaa cgtgctgggt tctaacggct ccgtgatccc attgttccgt
     2581 gaacagattg ccaagggcgg tcccgtgaca gtgacgcatc cggatatcat ccgtttcttc
     2641 atgctgatcc cggaggcctg ccggttggta ttggaggcgg gtacgatggg taacggtggg
     2701 gagatcttcg tcttcgacat gggcaaaccc gtgcgtatca tcgacttggc gaaacgtatg
     2761 attcagcttt cgggcgccaa gaacgtagag gtccggttta cgggtcttcg tgccggcgag
     2821 aagctgtacg aggaggtact gaacgacgag gagatcacgc tgcctacctt ccatccgaag
     2881 atcaagatcg ccaaggtacg ggagtacgat tatgatacgg tttgccaaga tatagatgaa
     2941 ctcgtcggcc taggccgctc gagggacgat atggccatcg tgggcaagat gaaggcgatc
     3001 gtccccgagt tcaaaagccg gcactccaag tacgagg
//
LOCUS       DBMDTB010000196         3006 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_7306_length_3006_cov_10.966265, whole genome shotgun sequence.
ACCESSION   DBMDTB010000196 DBMDTB010000000
VERSION     DBMDTB010000196.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 3006)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 3006)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3006
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_7306_length_3006_cov_10.966265"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..84)
                     /locus_tag="ACZPB4_16800"
     CDS             complement(<1..84)
                     /locus_tag="ACZPB4_16800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004325039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HIR1099909.1"
                     /translation="MDAFYASVEQRDNPELRGKPLAVGHAEQ"
     gene            complement(173..937)
                     /locus_tag="ACZPB4_16805"
     CDS             complement(173..937)
                     /locus_tag="ACZPB4_16805"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HIR1099910.1"
                     /translation="MENQATETRVLMHTNKGDIKLKLYNDTPLHRDNFIKLVQEGQYN
                     GLLFHRVIKDFMIQGGDVTSKDAPMNKQLGAGDLGYTVPAEFRYPKYFHKKGALCAAR
                     TGDEVNPEKASSASQFYIVTGKKYSEQELNQMEKQLEGRLKQEIFARLQNENKPKIME
                     FYRSGNKEELAILRDTLIGKTELEAEKRKDEVKLNPELREAYKNEGGVPFLDNQYTVY
                     GEVVEGMDVVDAIQSSKTNKQDRPTENIVINSVEIL"
     gene            complement(945..1616)
                     /locus_tag="ACZPB4_16810"
     CDS             complement(945..1616)
                     /locus_tag="ACZPB4_16810"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HIR1099911.1"
                     /translation="MRRILTMLFVSVFMLSLCPLHAQETETLVLIDTDMGKIKVKLFN
                     DTPLHRDNFIKNVKEHRYDGLLFHRVIKQFMIQGGDINSKDAPLDAHLGDGDLDYTIP
                     AEFVYPKYFHKRGMLCAARTPDEENPEKASSATQFYIVTGKFFTEMELDKMTKEKGIE
                     FTPEQKEAYMLEGGTPHLDGNYTVFGEVIQGMKVVDKIQFVETNADDRPTKNIKIKSM
                     KLIEK"
     gene            1814..>3006
                     /locus_tag="ACZPB4_16815"
     CDS             1814..>3006
                     /locus_tag="ACZPB4_16815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HIR1099912.1"
                     /translation="MRASILAILILGGIVLNIKAQFSYNEKAQAIPPASQPFGKEAFE
                     PTGHTVIRWLGNAGFLINSRGTCLMVDPMLKGFDMPLLINMPIAPKDVPHLDAVLITH
                     CDNDHYSVPTCTEMSSVCREYHSTFYVDSLMETQGLNSFGHRIGETFNVGPISIKLTP
                     AYHTWQNEYPGYTREFKVEDYCGFLMKTPDGLIWAPGDSRFLPEFLELPAPDVIFFDF
                     SDDSWHIGLEGAIKIANAYPKAQLLLSHWGTVDAPNMKPFNADPKMLEGRIRNPERVH
                     VLAPGEAFDLVALSSSEGEQCAETFIFPADAKASSEYNTGDVYVSLLKESGNTMIAHF
                     IFKPYSRNFWHYHPDAEQTLLVLDGEGYYQEEGGEKRVIRKGDVIVTPPNVRHWNGAT
                     PGSSIV"
BASE COUNT          723 a          678 c          664 g          941 t
ORIGIN      
        1 ctgctccgca tgcccgaccg ctaggggttt tcctcgcaac tccggattgt ctcgttgttc
       61 caccgaggca taaaaggcat ccatatcgat atgtatgatc tttctcaaga tagctctttt
      121 attactggta tttacgataa cccttcgtct gtttatgaag ccgataatcg cattataaga
      181 tctctacgga gttaatgacg atattctcgg tcggacgatc ttgcttgttg gtcttggagg
      241 actgtatggc gtctacgaca tccatgcctt ctaccacttc gccgtaaacc gtgtattgat
      301 tgtcgaggaa cggtacgcca ccttcgttct tgtaagcctc acggagttcc gggtttaact
      361 ttacctcgtc tttccgcttc tcggcctcca gctcggtctt gccaatcaag gtatcacgaa
      421 ggatcgccag ttcttccttg ttaccactgc gatagaattc catgatctta ggcttgttct
      481 cgttttgcag gcgggcgaat atctcttgtt tcagacggcc ttccagttgc ttttccatct
      541 ggttcaactc ttgttccgaa tactttttcc ccgttacgat atagaattgg gaggcggaag
      601 aggccttttc cgggttcacc tcgtctccgg tacgtgcggc gcaaagggct cctttcttgt
      661 ggaaatattt cgggtaacgg aattcggcgg gaacggtata gcccagatcg cccgctccca
      721 gttgcttgtt catcggggca tccttggaag ttacgtcacc tccttgtatc atgaaatcct
      781 tgatcacacg gtggaacagc aagccgttat attgcccttc ttgtaccaac ttgataaagt
      841 tatcacgatg taatggcgtg tcgttatata atttcagctt tatatctcct ttgttggtgt
      901 gcataagcac ccttgtctca gttgcttgat tttccatttt atacttattt ttctatgagt
      961 ttcattgact tgatctttat gttcttcgtg ggtctgtcat cggcgttcgt ctcgacgaac
     1021 tgtatcttat ccacgacttt cataccctgt ataacctctc cgaataccgt atagttcccg
     1081 tccagatgag gcgttccgcc ttccagcata taggcttctt tttgctccgg agtaaactcg
     1141 atgcctttct ccttggtcat cttatctagc tccatctccg taaagaactt tccggtcacg
     1201 atatagaatt gagtcgcaga tgaggccttc tcaggatttt cctcatccgg ggtacgtgcg
     1261 gcacagagca ttccccgctt atgaaaatat ttcggataca cgaactctgc ggggatggta
     1321 taatctaaat ctccgtcgcc cagatgcgca tccaaaggag cgtctttcga gttgatatcg
     1381 cctccttgta tcatgaattg cttgataacc cgatggaaca ataatccatc gtaacggtgt
     1441 tcttttacgt tcttgataaa attatccctg tgcaacggcg tgtcgttgaa cagtttcacc
     1501 ttgatcttac ccatatccgt atcaatcagc accaatgtct cagtctcttg cgcatgcagc
     1561 gggcatagcg aaagcataaa taccgaaaca aacaacatcg taagaatccg tctcatattt
     1621 atttctatta gttttagatg gacaaaaata agaataaata tcgatatcta tgatcaaagg
     1681 aataggtcta aacatgattt ctttggtagg aaaccgtaat agcgttacaa acatctgtaa
     1741 tatatgcaca tcgttttatg ttgaatctag gtaattttgt catagaaatt taaaactcta
     1801 aattcaatat actatgagag caagtatctt agctatttta attttagggg ggattgtctt
     1861 aaacataaag gctcagtttt cttataatga aaaggctcaa gccatccctc ctgcatcaca
     1921 acctttcggc aaagaggctt ttgagccaac cgggcatacg gttatacgct ggttggggaa
     1981 cgctggcttt ctgattaata gccgtggtac gtgtttgatg gtcgatccta tgttgaaggg
     2041 atttgatatg cctttgttaa taaatatgcc gatcgcccct aaagatgttc cccatttgga
     2101 tgcggtattg attactcatt gcgacaatga tcattacagt gttcctactt gtacggaaat
     2161 gtcttctgta tgccgggaat atcattctac attctacgtg gattctttga tggaaacaca
     2221 gggtttgaac tctttcggac atcgtatcgg ggagactttt aatgtcggtc cgatttctat
     2281 caagttaacc ccggcttacc atacgtggca aaatgagtat ccgggatata cgcgtgaatt
     2341 taaggttgaa gattattgtg gtttcctcat gaaaacaccg gatggcttaa tttgggcacc
     2401 gggagattcc cgctttcttc ctgagttctt ggaattacct gccccggacg tgattttctt
     2461 tgatttctcg gatgattcat ggcatatagg attggaggga gccataaaga tcgcaaatgc
     2521 ttatcctaaa gcgcagcttc tcctgtctca ttggggaacg gtggatgctc ccaatatgaa
     2581 accatttaat gctgacccta aaatgctaga agggcgtatc cgtaatccgg aacgtgttca
     2641 tgtcttagcc ccgggagaag cttttgacct tgtagctctc agctctagcg agggtgaaca
     2701 atgtgccgaa acctttattt tccctgccga cgcaaaggct tcgtcggagt ataatacggg
     2761 ggatgtctat gtctccttgt tgaaggagtc tggtaatacg atgatcgcac attttatatt
     2821 caaaccttac agtcgtaatt tctggcatta ccatccggat gccgagcaaa ccttgttagt
     2881 acttgatgga gaaggatatt atcaagagga aggaggagag aaacgtgtga tccggaaggg
     2941 tgatgtgatc gtgacacctc ctaatgtacg ccattggaat ggggcgacac cgggtagctc
     3001 tatcgt
//
LOCUS       DBMDTB010000197         2948 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_7500_length_2948_cov_9.959607, whole genome shotgun sequence.
ACCESSION   DBMDTB010000197 DBMDTB010000000
VERSION     DBMDTB010000197.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 2948)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 2948)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2948
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_7500_length_2948_cov_9.959607"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..>2948
                     /gene="porU"
                     /locus_tag="ACZPB4_16820"
     CDS             <1..>2948
                     /gene="porU"
                     /locus_tag="ACZPB4_16820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0071806 - protein transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type IX secretion system sortase PorU"
                     /protein_id="HIR1099913.1"
                     /translation="KLSYADLKNMGFSDPSKVSVHGYGGWPLDEDFSKEYIDDVPSTP
                     VWRGSDYLLFYGKGSVKWEYDSSSQTFVHTNNPYSLYGYYFVTDATPTNDMTSVAQAS
                     GASTRITTYDDYLLHEQELVSVNQSGREFFGEDFSGARPRTISTFSSIPGITGADGKV
                     TMRFISRINSGSGTASLSINDSELLDITIPSIQTVSSNVRSYTKAIPGTTTALWKGSK
                     SEKNNVVVSYSSSGHTNVRLDYIRMQFVRTLRPYGACTFFRSLTSVGNASRFVISEAN
                     SNTLVFDVTDALNVKRVEADLNGSELSFTIPAGRLREFVLVQTNQTFPSPEVVGEVAS
                     SNLHGLEQRDMIIISAPSLVQQAERLAVAHREKDGLTVEVVTPEAIYNEFSSGTPDAT
                     AYRRLMKMFYDRSSSLGNPPKYLLLFGDGIYDNRGISGEVQGVSWSNMLLTFQSQESL
                     NVYSYATDDYFAFLEDNSGSNFSRDKMCLGVGRFPIRTVTEATQMVDKTISYMENKDS
                     GSWKNNVTFVADDGNNEDSFTTNHMKQADQLAEAIEEMQPGFLVNKVYFDAYKRSSLG
                     TYPDVHNEIEKLLKSGQLLINYTGHGSTTHWADESVWTQTDINNSSYKHLPVWVTATC
                     DFTRFDDVKTSAGESVFLNPTSGGIALFTTTRVVFSGNNANLNKALIDNLFQEGANSR
                     YTLGEAMMYTKRQLNDSNKLNFILIGDPALKFAYPEYKARVTAVNGEAVSDEPFEFKA
                     LSRITVEGEILNPSGSFAADFTGVLSSTIFDSQSSITTLGNSSEKFTYLDYPNTIYIG
                     RDSVRNGKFSFTFMVPKDISYSNKKGKLNLYASSETKEAQGSFFDFIVGGTSDTAETD
                     TIGPEIRQIYLNDSSFVSGDKVNTTPYFVAKLWDKSGVNITGSSVGHDMMLTIDSMPS
                     MSYNLNSYYALLPDSENEGLVQFSIPELEPGMHTAEFKVWDILNNSTTYTFTFEVAEG
                     LKPNLIEMYAT"
BASE COUNT          770 a          546 c          758 g          874 t
ORIGIN      
        1 aaattatcct atgcggattt gaagaatatg ggtttctcgg acccatcgaa agtctctgtc
       61 catggctatg gaggatggcc cttggatgag gatttcagta aagaatatat cgatgatgtc
      121 ccttctactc cggtttggcg tgggagtgat tacctgttat tctacgggaa agggtcggtt
      181 aaatgggaat atgactcgtc gagccagaca ttcgtgcata cgaataatcc ttattctttg
      241 tatggttatt attttgtgac cgatgccaca cccacgaatg atatgacttc cgtggctcaa
      301 gcgagtggtg cttccactcg gattacgact tatgatgatt atctattgca tgagcaagag
      361 ttagtctccg taaaccaatc cggccgggag ttttttggag aggactttag tggggcacgc
      421 cctcgtacaa tttctacctt ttcttctatc cccgggatta cgggtgcgga cggtaaggtg
      481 accatgcgtt ttatctcaag aattaactct ggttccggta cggcttcttt aagtatcaat
      541 gactccgaat tgttggatat aaccatacct tctatccaaa cagtaagctc gaatgtcaga
      601 tcgtatacaa aggcgattcc cgggacaacc accgcgttat ggaagggatc aaaaagtgag
      661 aaaaataacg tagtggtttc ctatagttca agtggacata cgaatgtacg tttggactat
      721 atccgtatgc aatttgtccg tacgttgcgc ccttatgggg cttgtacttt tttcagaagc
      781 ttgacttctg taggaaatgc gtctcgcttt gttattagcg aggcgaattc gaataccttg
      841 gtgtttgatg tgaccgatgc gttaaatgtg aagagagtgg aagccgatct gaatggttct
      901 gaactttcat ttacaatacc agcgggtaga ttgagggagt ttgtgttggt tcaaaccaat
      961 caaacatttc cttctccgga agtcgtggga gaagtcgctt cctcgaatct gcatggtttg
     1021 gaacagaggg atatgattat tatatcggct ccgtctttgg ttcagcaggc ggagcgtttg
     1081 gcggttgcgc accgtgagaa agatggcttg actgttgaag tcgtaactcc agaggcgatt
     1141 tataatgagt tctctagtgg aactccagat gcgacggcat atcgtcgttt gatgaagatg
     1201 ttttacgatc gtagttcttc tttaggtaat cctccaaaat atttattgct tttcggagac
     1261 gggatctatg ataatcgggg gataagcggt gaggtgcaag gtgtttcatg gagtaatatg
     1321 ctcttgactt tccagtctca agagtcattg aatgtctact cttatgcgac agatgattat
     1381 tttgcgtttt tagaggataa ttccggcagt aattttagcc gagataagat gtgtctgggt
     1441 gtcgggcgct ttccaatccg tacagtaacg gaggcgactc agatggtgga taagacgatt
     1501 tcttatatgg agaataagga ttcgggtagt tggaagaata acgtgacatt cgtggcggat
     1561 gatggaaata atgaggatag tttcacaacg aatcatatga agcaggcaga tcagcttgct
     1621 gaggccattg aagagatgca acccggtttt ctagttaata aagtgtattt cgatgcttat
     1681 aagcgtagca gcctcgggac ttatccggat gtgcataatg agattgagaa actattaaaa
     1741 agtggtcagt tgttgattaa ttatacgggg catggcagta cgacccattg ggcggacgaa
     1801 agcgtatgga cacaaaccga tatcaataat tccagctata agcatctgcc ggtgtgggtg
     1861 acggctacct gcgattttac ccgttttgac gatgtgaaaa cttctgcggg tgaatctgtt
     1921 ttcttgaatc ctaccagtgg gggtatcgct ttgtttacga cgacccgtgt cgtgttctcc
     1981 ggtaataatg cgaacttaaa taaggcactc attgataacc tgttccaaga aggtgcgaat
     2041 agccgttata cgcttggaga ggcgatgatg tatacgaaac gtcaactcaa tgactcaaat
     2101 aaattgaact ttatcttaat cggagacccg gcgttaaagt ttgcatatcc agagtataag
     2161 gctcgggtga cggctgtgaa tggagaagct gtttctgatg agccttttga gtttaaggcg
     2221 ttatcccgga ttacggtaga gggtgaaatc ttgaatccgt caggttcttt tgccgcggat
     2281 ttcacgggcg tattaagctc gaccatattt gatagccaaa gttccattac gactttaggg
     2341 aatagctctg agaaattcac ttatctcgat tatccgaata cgatttatat aggtagagac
     2401 tcggttcgaa atggaaagtt cagctttact tttatggtcc cgaaggatat ctcttattcc
     2461 aataagaaag gtaaattaaa cctatatgcg tcttccgaga caaaagaggc gcagggttct
     2521 tttttcgatt ttatcgtggg ggggacttcg gatacggcgg agactgatac gatcggtccc
     2581 gagatccggc agatctattt gaatgattcc agttttgttt cgggcgataa ggtaaacacg
     2641 actccttatt ttgtagcgaa gctgtgggat aagagcggcg tgaatataac cggcagtagc
     2701 gtagggcatg atatgatgtt gacgattgat agtatgccct ctatgagcta taacttaaat
     2761 agttattatg cgttgctacc agatagtgag aacgaaggac ttgtccagtt ctccatccct
     2821 gagctggagc cgggaatgca tacggctgag tttaaggtgt gggatatctt aaataactcc
     2881 acgacctata cctttacttt tgaggtggcg gaagggttga aacctaatct gatcgagatg
     2941 tatgccac
//
LOCUS       DBMDTB010000198         2938 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_7534_length_2938_cov_11.263306, whole genome shotgun sequence.
ACCESSION   DBMDTB010000198 DBMDTB010000000
VERSION     DBMDTB010000198.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 2938)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 2938)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2938
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_7534_length_2938_cov_11.263306"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..300
                     /locus_tag="ACZPB4_16825"
     CDS             <1..300
                     /locus_tag="ACZPB4_16825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008773993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HIR1099914.1"
                     /translation="PYFFKGKAGEGIGGPHIGFNYIWPMSLIMRATTSNDEKEIRYCI
                     ETLRDTDGGTGFMHESFHKDNPSDYTRSWFAWTNTLFGELIVKLQSEGKLKDLLG"
     gene            418..1995
                     /locus_tag="ACZPB4_16830"
     CDS             418..1995
                     /locus_tag="ACZPB4_16830"
                     /EC_number="3.1.6.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005862019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase family protein"
                     /protein_id="HIR1099915.1"
                     /translation="MKTNKLFILTGLAAIASTSCSQKENTSGQPAKPMNILYIMTDDH
                     SFQTISAYDKRYIQTPNIDRIANEGVRFTNSFVANSISGPSRACMLTGKHSHKNGFID
                     NAHTFDGSQQTFPKLLRKAGYQTAMIGKWHLTSDPTGFDYWNILVGQGDYYNPIFIDN
                     GEKRQIEGYATNITTDLALDWLDNKRDKSKPFCLLLHHKAPHRTWMPDTCDLRLYDDV
                     TFPLPENFYDDYAGRIAASEQEMSIIKDMDIVYDLKMADKENEIHSSNADLEKYGREL
                     YNRMNPDQKAAWDAYYDPIIQDFKAKKRTGKELAEWKYQRYMHDYLRVIHSVDRNIGI
                     VLDYLEKNDLLDNTLIVYTSDQGFYMGEHGWFDKRFMYEESFRTPLLMRLPGGKKGDI
                     PQLVQNIDYAPTFLELAGAPIPADIQGESLLPLLKGERPENWRNSLYYHYYEYPAEHS
                     VKRHYGVRDDRYKLIHFYNDIDVWELYDLQEDPHEMNNLYGKPSYEAVMKRMRDELYK
                     LQKQYDDPVGIRFNVSD"
BASE COUNT          826 a          703 c          690 g          719 t
ORIGIN      
        1 ccttacttct tcaagggaaa ggccggcgag ggcatcggcg gtccgcatat cggtttcaac
       61 tatatctggc cgatgagctt gatcatgcgt gctacgactt ccaacgacga gaaggagatc
      121 cggtattgca tagagacgct tcgtgatacg gacggaggca cgggcttcat gcacgagtct
      181 ttccataagg acaatccttc cgattacacc cgctcgtggt tcgcttggac gaatactctg
      241 tttggcgagt tgatcgtgaa gctgcaatcc gaaggcaagc tgaaagacct cctcggctaa
      301 taccaccaag gttaatatca ccaattgtag agacgggaca tgccctgtct ctacaagtct
      361 gtagctgagt gtatttaggc aaaatcaatc aaaacaacat aaatctaagc ggaatacatg
      421 aaaacaaata aactattcat tctgacaggt ctggcggcga tagcctccac ctcctgtagc
      481 caaaaagaga atacgtccgg gcagcccgcc aagcccatga atatccttta tatcatgacg
      541 gacgatcact ccttccaaac catcagtgcc tacgacaagc gatacatcca aacccccaac
      601 atcgaccgca tcgcaaacga gggcgtacgt ttcaccaata gcttcgtagc caactccatc
      661 agtggcccca gccgtgcctg catgctgacc ggcaagcaca gccacaagaa cggcttcatc
      721 gataacgccc ataccttcga cggctcgcag cagaccttcc cgaagctatt gcgtaaagct
      781 ggctaccaaa ccgccatgat cggtaaatgg cacctcacct ccgatcccac cggtttcgat
      841 tactggaaca tcctcgtagg ccaaggcgat tactataacc ccatcttcat cgataacggc
      901 gagaagcgtc agatcgaagg gtacgccacg aacatcacga ccgatctggc tcttgattgg
      961 ctggacaata aacgagacaa gagcaagcct ttctgcctcc tgctgcacca taaggccccg
     1021 caccgtactt ggatgcccga tacctgcgac ctgcgtcttt acgatgatgt gaccttcccg
     1081 ctgcccgaga acttctacga cgattacgcc ggccgcatcg ccgcctcgga gcaggagatg
     1141 agcatcatca aggatatgga tatcgtatac gacttgaaaa tggccgataa ggagaacgag
     1201 atccattcct ccaacgccga tctggagaag tacggccgtg agctttataa ccgcatgaat
     1261 ccggaccaga aagccgcttg ggacgcctat tacgatccga tcatccaaga cttcaaggcg
     1321 aagaaacgca cgggtaagga gctggccgag tggaaatacc agcgttatat gcacgattac
     1381 cttcgggtga tccattccgt ggatcggaac atcggtatcg tgctcgatta tctggagaag
     1441 aacgatttgc tggataacac gttgatcgtc tacacctccg accaaggctt ctacatgggc
     1501 gagcatggct ggttcgacaa gcgcttcatg tatgaggaat ccttccgcac cccgttgctg
     1561 atgcgtctgc cgggtggcaa gaagggtgat atcccgcagc tcgtgcagaa tattgattac
     1621 gcccccactt ttttggaact ggccggagcc cccatcccag ccgacatcca aggcgagtcc
     1681 ttgcttccct tgctgaaagg cgagcggccg gagaactggc gtaactccct ttactatcat
     1741 tactacgagt atcccgccga gcattccgtg aagcgtcatt acggcgtacg tgacgatcgt
     1801 tataaattga tccatttcta caacgacatc gacgtatggg agctttacga cctccaagaa
     1861 gatccccacg agatgaataa cctttacggt aagcccagtt acgaggcagt gatgaaacgc
     1921 atgcgagacg agctttataa gctgcaaaaa caatatgatg atcctgtggg aatacgcttc
     1981 aatgtgtcgg actgatgaga gcggacattc gtgttctgtt atcagatttt ttaattagtt
     2041 gtggattaag gtgcataaag gacttggaac ttgggggatg agaagttgag tctttgcgct
     2101 tgatgactta gctctttgcg ttctttgatt taagtcattg gcttgaagga attaagtcta
     2161 tcgtatggct cttctttgct tatgcgtgta tcgaattaaa aaatgactat aggcaggttt
     2221 caagtttcaa ggtttcatga aacctttttc ttcacacaca cgatacgtac attatatagg
     2281 tttcaaataa atccctttat gtttgttatg cgggatggat agcctcgaag aacttgcgta
     2341 gccacgacat gatgttttta cccgaggcgg acggagcgat catgaggaac tgtattatat
     2401 gtacttgtgc gtgtgtgagg aaaaggggtt cgtgaaacct tgaaacttga aacctatttc
     2461 catgcccatc cagatattgt caacatcagt acagataaat atatgtgcct ttatcgtgtg
     2521 cgtacattaa acgtaaggat tgttgagcca tgagaaaaaa cttgaaaaat aatgccgaaa
     2581 atgtttggag gttatgtttt atagcgttac ttttgcaccc gcattcgaga gagaacggcg
     2641 ataccgaaat aatgaaacaa atttttcttg aaaaaagttc tgaaataatt tggaagttta
     2701 aaagaaaaac acttatcttt gcatccacgt tcgcaaaacg aaagcgacaa aagagttctt
     2761 tgagagattt acataattca acaagtagta caagtattag gaaaattaat tttccggatt
     2821 gataccgtca agaagaggta tgactttgga ctacgataaa cggattccgg agcgaggata
     2881 tgataaaaca atttaaacaa cgaagagttt gatcctggct caggatgaac gctagcga
//
LOCUS       DBMDTB010000199         2914 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_7610_length_2914_cov_10.444010, whole genome shotgun sequence.
ACCESSION   DBMDTB010000199 DBMDTB010000000
VERSION     DBMDTB010000199.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 2914)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 2914)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2914
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_7610_length_2914_cov_10.444010"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            443..1723
                     /locus_tag="ACZPB4_16835"
     CDS             443..1723
                     /locus_tag="ACZPB4_16835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2262 domain-containing protein"
                     /protein_id="HIR1099916.1"
                     /translation="MEKEQTNENSWEFHLTDKIAQLSKMTLEMHTEFWLSTLQTWFHG
                     YQTPEEYKATIWGREVDLCISIAPLETPTEKLPIIEEKSAKGKNELLPPEQQAYVDEL
                     KKKIKALKKLLPPKVDEALEQRYLDYMNAERIKAIIQDCTKIWSNPDLPVEEKISQLI
                     PYKIELYDLVRNVQLPDDLMRADTNISITMATIQFFAQSVEKNAKKNKIKTPKQVRQL
                     VKFTNDIITRMDEGQNKLNGVERDMTKEESKAYDAYLDIKIGARSALHSFEKRLELYE
                     RLWEMPSVSTGTKIECLNEAIKLIRKQCGKNLEPRCPHESLIRKHLKAISGYMNKLEE
                     EGEAIWQLRMADELLPTANAWWEDCELPALSREEFASQVELQSVHIETKEKEDGSIHY
                     ELELFFQDTEDTFAGHFLYADIEDHEVKEITLMG"
     gene            complement(1769..2272)
                     /locus_tag="ACZPB4_16840"
     CDS             complement(1769..2272)
                     /locus_tag="ACZPB4_16840"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HIR1099917.1"
                     /translation="MQYTDKYRSPLGEITLASDGDHLTGLWFDGQKYFAATLSAEHQE
                     RELPIFEQAKEWLDSYFMGKIPSFTPPIHLEDTPFRLAVWDLLSKIPYGEVVTYKELA
                     GEIARQKGIPSMSTQAIGGAVGHNPISIIIPCHRVVGSDGSLTGYAGGIDKKRSLLTI
                     ERAPKVS"
     gene            2430..2912
                     /locus_tag="ACZPB4_16845"
     CDS             2430..2912
                     /locus_tag="ACZPB4_16845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008148926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin"
                     /protein_id="HIR1099918.1"
                     /translation="MILSRNLSEAFNAQVNAEMWSSNLYLSMSVYFQKAGLNGFAHWM
                     KKQAAEELEHAHKLIDYALDRGGDITIGQINVVPTGWGNPLEVFEHVYKHECYVSELI
                     DKLVDIAEADKDHASRDFLFWFVREQVEEESTAKEIVDQLKNYGECHYAIMDHRLGKR
                     "
BASE COUNT          892 a          565 c          691 g          766 t
ORIGIN      
        1 tgtggcaaaa tattttcaat agctatcagc tgtggaaaaa gaggaaaaat gagctagaat
       61 aataaatgcg acccggaaaa aggcggcaca ccgaaataac gatggagccg cctcattaac
      121 tttctttcct atcctcttat cagtaaattg aagcaaatcc caaatatgaa ataagctata
      181 tagcagaaaa cggaaacacc tagagaaaca agcagttgtt tcatgaaaga ctctctgtaa
      241 tatgataaca ataattgccc catggggtat gaattgttga tttgggcaaa acgtggtgaa
      301 ttacatggaa cagcgttcgt tacgctttga agctataacc atcatatatt tatcttaatt
      361 gcaggatata cgtttacggg gaaaacttat tggctcaaag gtgatcaagt tgtctatttc
      421 agtataataa ttattcatac ttatggaaaa ggaacaaacg aatgaaaata gttgggaatt
      481 tcatctgaca gataagatcg cccagctttc caaaatgacc ttggaaatgc atacggagtt
      541 ttggcttagt acactccaga catggtttca tggctatcaa acacccgaag agtataaagc
      601 gacgatttgg gggagggagg tagacctatg catctccatc gctcccttgg agacaccgac
      661 cgagaaatta cctatcattg aagagaaatc ggcaaaaggt aagaatgagc tgcttccccc
      721 ggaacagcaa gcctacgtag acgaactcaa aaagaagata aaagctctca aaaaactcct
      781 gccgcccaag gtggacgaag cgttagagca acgctatttg gattacatga acgccgagag
      841 gattaaggca atcattcaag actgcaccaa gatatggagc aacccggatt tgcccgttga
      901 agaaaaaatc agtcagctca ttccttataa aattgaatta tatgaccttg tgcgtaatgt
      961 ccaactgccg gatgatttga tgcgtgcgga tacgaatatt tcaattacaa tggccaccat
     1021 tcaattcttt gcacaaagcg tagagaaaaa tgcgaagaaa aacaaaataa aaacacccaa
     1081 gcaggtacgt caattagtga aatttaccaa tgacatcatt actcgcatgg atgagggtca
     1141 gaataagcta aacggcgttg agcgagatat gactaaggaa gagtctaaag cctatgatgc
     1201 ttatcttgat ataaagattg gagcaaggtc tgcccttcac tcgtttgaaa aacgattgga
     1261 gttatacgag cgactttggg aaatgccctc ggtctctacc ggtactaaga ttgaatgttt
     1321 gaatgaggcc atcaaactta tccggaagca atgcggtaaa aacctggagc cccgttgtcc
     1381 gcacgaatcc cttatccgga aacatctgaa agctattagt ggctatatga ataagctgga
     1441 agaagaaggg gaagcgatat ggcaattgcg catggccgac gaattgctcc cgacagcaaa
     1501 cgcatggtgg gaagattgtg aacttccggc attgtccaga gaggagtttg cctcccaggt
     1561 agaattgcaa tctgttcata tagagaccaa ggagaaagaa gacggctcca tccattacga
     1621 actggagctt tttttccaag acacggaaga cactttcgcc ggccacttcc tatatgctga
     1681 tatagaagat catgaggtga aggagataac gttaatggga tagttacatt ctatatttgt
     1741 ccacaaggat ttgcaaggta aagtctcttt acgatacttt tggggcccgt tcgattgtaa
     1801 gcaggctcct ttttttgtcg atacctccag cgtatccggt taggctgcca tcgctgccta
     1861 cgacacggtg gcaggggatg atgatactga ttgggttatg gcctaccgct cctccgatcg
     1921 cttgcgtaga catgctcggg ataccttttt gccgggcgat ttcgccggcg agctccttgt
     1981 aggttacgac ttcgccataa ggtattttgc tcaataagtc ccataccgca agtcggaaag
     2041 gcgtatcctc cagatggata ggaggggtga agctgggaat cttacccatg aaatagctat
     2101 ccagccactc tttggcttgt tcgaatatcg gcagttctct ttcttggtgt tccgccgata
     2161 aagtggcggc aaaatatttt tgcccgtcga accataatcc tgtcaggtgg tctccatcgc
     2221 tggctagggt tatttctccc aagggagatc gatatttgtc ggtgtattgc atgatgttta
     2281 tcaaataagg gcgtaagtta gaaaaatttt cgaaagtagc caatatctaa gggcggaaat
     2341 gagataagga atcctacttt tatttatatt tgcatagtga aatttcgtga acggataata
     2401 cttcaacatt tttaaacaat gataaaatta tgatcttaag tagaaattta tcagaggcgt
     2461 tcaatgccca agttaatgcg gagatgtggt cttcgaattt gtatttgtca atgtccgtgt
     2521 atttccagaa agcagggttg aacggtttcg cccattggat gaagaaacaa gcggctgagg
     2581 aattggagca tgctcataag ttgatcgatt acgccttgga tcgtggcggc gatattacga
     2641 tcggccagat caacgtggtt ccgacaggct ggggaaatcc gttggaggta ttcgagcatg
     2701 tttacaaaca cgagtgctat gtatcagagt tgatcgacaa attggttgat atcgccgagg
     2761 ctgataagga tcatgcttcc cgtgatttct tgttctggtt cgtacgcgag caagtagagg
     2821 aagaatctac ggctaaagag atcgtggatc aattgaagaa ttatggggaa tgccattacg
     2881 ccattatgga tcatagatta ggaaagagat aata
//
LOCUS       DBMDTB010000200         2883 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_7731_length_2883_cov_8.975198, whole genome shotgun sequence.
ACCESSION   DBMDTB010000200 DBMDTB010000000
VERSION     DBMDTB010000200.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 2883)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 2883)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2883
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_7731_length_2883_cov_8.975198"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..1017
                     /gene="thrC"
                     /locus_tag="ACZPB4_16850"
     CDS             <1..1017
                     /gene="thrC"
                     /locus_tag="ACZPB4_16850"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004795 - threonine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HIR1099919.1"
                     /translation="HGPTLAFKDVGGRFMARLLGYFIKKEGLKQVNVLVATSGDTGSA
                     VANGFLGVPGIHVYVLYPKGKVSPIQECQFTTLGQNITALEIDGTFDDCQALVKSAFM
                     DEELNRHMKLTSANSINVARFLPQSFYYFNAYAQLDKLGKADELVVCVPSGNFGNITA
                     GLFAYWMGLPIKRFVAANNRNDVFLEYLNTGTYTPRPSVATLANAMDVGDPSNFARII
                     DLFGAFNDPHKEICALISGHRYTDEEIASTMRAVYKETGYILDPHGACGYQGLLDSDL
                     SETETGLFLETAHPAKFKGTVDKILEADIEIPAKLKAFMEGTKQSIELAKDFEGFKSF
                     LMSR"
     gene            complement(2183..2623)
                     /locus_tag="ACZPB4_16855"
     CDS             complement(2183..2623)
                     /locus_tag="ACZPB4_16855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF695 domain-containing protein"
                     /protein_id="HIR1099920.1"
                     /translation="MRLSDVWFTALSENESGQMITVYGRDELNEFTESGKFKERVEIT
                     WKYEGDGRGLPCDDLGEKMEAVEEALRKAMEKKDKLAILTGVYTGGGEKVWVFYTRTV
                     RVFGERLNEALAPFELLPISIYTEMDPDWEEYKDMYEMKEWAVD"
BASE COUNT          817 a          693 c          603 g          770 t
ORIGIN      
        1 cacgggccta cattggcctt taaggatgta ggagggcgct tcatggctcg tctgctcggt
       61 tatttcataa agaaagaggg attgaagcaa gtaaacgtat tggtagctac ttccggcgat
      121 acgggaagcg ccgtcgccaa cggattccta ggcgttccgg gcattcacgt gtatgtgctt
      181 tatcccaagg gaaaggtcag cccgatacag gaatgccagt tcacgacatt aggacagaac
      241 atcacggcat tggagataga cggcacgttc gacgattgcc aagcgctggt taaatccgcc
      301 tttatggacg aggaattaaa ccgtcatatg aaactgacct cggcgaactc catcaacgta
      361 gcccgtttct tgccccaatc gttctactat ttcaacgctt acgctcagct ggacaagctg
      421 ggaaaagcgg acgagctggt tgtttgcgtg ccgagcggta atttcggaaa catcaccgcc
      481 ggattgttcg cctattggat ggggctccct attaaacgtt tcgtagcggc aaacaaccgt
      541 aacgacgtat tcttggaata cctgaataca ggaacttata caccccgccc atcagtcgcc
      601 accctagcga acgccatgga tgtaggcgat ccgagtaatt tcgcccgtat catcgaccta
      661 ttcggcgcat tcaatgatcc tcataaagaa atatgcgcac tgatctccgg acatcgctat
      721 acggacgagg aaatcgcctc tacgatgcga gccgtctata aagagacggg atatatcctc
      781 gacccgcacg gagcctgtgg ctaccaagga ttactagaca gcgacctaag cgagaccgag
      841 acgggtctat tcctcgagac cgcccatccc gccaaattca aaggaacggt cgataagata
      901 ttggaggcag atatcgagat cccggcgaaa ctgaaagcct tcatggaagg aaccaagcaa
      961 agcatcgagc tggcaaaaga tttcgaggga ttcaaatctt tcttgatgag ccggtaaaaa
     1021 gaagaatagt tttcgtaatt gatataaaat ggaaggtgta gcaaattgat attatcgata
     1081 tttgccacac cttccatttt tatcacctaa gacatacaaa aacaggcgag aatttcaaaa
     1141 agaaattccg taagcaagct tttcttccga aaagtcatgt tattaaattc gattaattat
     1201 aagccaaatg tataattatt ggagaaatag agtttttata ggatcagtcg ataattggtg
     1261 gggataatta ttttcatcta tttaaaatct ctacctttgc tctatggaaa cgaataaact
     1321 ttatacatta gctcagaaag tactaccaag tgcagttctt acgtatttta atatcgtcaa
     1381 catagaaagc acatccaccg agattttcat ccatcttgat gaaaagatga gtgacagtct
     1441 taatatacat taaccgtctc tcccccgatg gttatcggga aatggcagag gaactataga
     1501 tacaagtggc ccatttgtct ttttgacaac ttgtaatctg aagtcccgga gaatcgatta
     1561 ttccgtaccc aagtgcgtct cgcttccaaa ttcgagagaa aaaaacagca attctctgtt
     1621 tgatagctgt ttgctaaaaa acggcctttc gttccagccg aaataattca ccctagttca
     1681 tgttttacgg ccgtaaggcg gtaataatgc ccaacgctac cgcatgtgaa ggccgatgcc
     1741 tatatatgtg taggcttacg ccactatatg tgtagcttga cgcgactata tgtgtgggtt
     1801 gacactgcta tatatgtgag ttgatacagc catatgtgta ggttgatacg tatatattcg
     1861 ttaaaaagcg acgcttatcg tgttaaaaag cggtggtggc agcttgttcg cgctccccgc
     1921 ttacgctcgt tggcttttat agccagagag ccgtgtcgta aaaaagaagg tatttcaatc
     1981 aaaaagatac cattcatcgc attaagctga catccacgat tcttgtttta tccctttgaa
     2041 ttaagtctgt cctcaataaa tatcgggtga gccattggta gacacgggcg gggtagaggc
     2101 gtacaagcgg gtgaaggtgc gcatattgat ccccatgaac tcgccgtact cacctttcac
     2161 gccaaactcg aagcacagga tctcaatcca ccgcccactc tttcatctca tacatatcct
     2221 tatattcttc ccaatccgga tccatctcgg tataaataga gatgggcagt aactcgaaag
     2281 gagccaaggc ctcattcaag cgttcgccga atacacgcac ggtacgtgtg taaaacaccc
     2341 agaccttctc tcctcctccg gtatagacac ccgtcaggat agccagcttg tctttctttt
     2401 ccatcgcctt acgaagcgct tcctccacgg cctccatttt ctcgccaagg tcatcgcaag
     2461 gaaggcctct cccatctccc tcgtatttcc aagtgatctc gacacgttcc ttgaacttac
     2521 cggattcggt aaactcattc aactcgtccc gcccgtaaac ggtaatcatt tgccctgact
     2581 cgttttccga gagagccgta aaccatacat cgcttaatct catcgtccct atctataaat
     2641 gatacgctac taatttgaca tgataaaaaa atgaagctaa gtaacattgc caacacactt
     2701 aacttactag gcaatgtcac ttagcttact tggcaaagta agttaacttc attcgacaac
     2761 gaagttaact tcgtaaaaca tgtattatct ctttcctaat ctatgatcca taatggcgta
     2821 atggcattcc ccataattct tcaattgatc cacgatctct ttagccgtag attcttcctc
     2881 tac
//
LOCUS       DBMDTB010000201         2807 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_7995_length_2807_cov_10.485957, whole genome shotgun sequence.
ACCESSION   DBMDTB010000201 DBMDTB010000000
VERSION     DBMDTB010000201.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 2807)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 2807)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2807
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_7995_length_2807_cov_10.485957"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..>2807
                     /locus_tag="ACZPB4_16860"
     CDS             <1..>2807
                     /locus_tag="ACZPB4_16860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004866 - endopeptidase inhibitor activity
                     [Evidence IEA];
                     GO_process: GO:0010951 - negative regulation of
                     endopeptidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-2-macroglobulin family protein"
                     /protein_id="HIR1099921.1"
                     /translation="RLKADRLGKLVRLKPDVPGRWAFENNRTLVFKPEKGFERNTSYQ
                     VNADLSEWFEAEGKDKRFAFGFTTLPLALRGNLESMDINKKNENGYDLTAVLFTPDKE
                     SPGTVESLVDFSEKVDATWQHSPDGKKHEVTLTNVPAGMKGERILRLSVSSNKLGVEK
                     ADVVTVSIPDQNDFSVYDVVYVSEPECYVEVAFTKLLDSAQDMRGLAFIAGNTSETVN
                     VDGNKLRLYPDADLREKGAMNIHLNQGIRSKSGLNLKEAVVRQVVANEQKPNVRFIGK
                     GVIIPQSTQLSVPFQAIYLRGVTVSVIKILEQNIGQFLQSNNLDESGELMRVGRLIAR
                     KTIFLDEEGLDLSRWNTFAIDLKRLIEPEPGAIYRLELSFDRSLSVYPCGNDTVVLSK
                     EQILASDEIRFKEESARFDEGGYYYYRQYDWSDYNWEKRDDPCSDSYYFNKVEGKNVL
                     ATNLGLVALMGQDNDMTVLVHNIQSTEPERGVTVTAYNYQHQALASGTTDDKGQVRLD
                     LSSGRSFYLIASQGTQRSYLRVDNGSALSLSSFDVSGEVVQKGIKGFIYGERGVWRPG
                     DTLHLGFMLNDRAKQLPAEHPVVMELYNPLGQMYARKTQTRGELGLYAFDFVTEADAP
                     TGAWNVKAQVGGVSFSKRLRIESIKPNRLKIALSMPEKTLLRGEPMDARLHVVWLQGA
                     IARNLKYDIQGTFIATPTTFEGYKGFYFDDPSRVFNTEESKLISGVTNERGDATVQAR
                     FELGSTAPGMLLANLVTRVYEESGDFSIDADRMLYSPYRRYAGIKSPQKEKEQLNTGA
                     NYTYEVASVDYLGKPQANTELDVKVYKVYWYWWWDSNSSGLANYVSDSFNKPVKTFTV
                     RTDGDGRGTFQLSFPDKEWGTYFISVKDKESKHSTGVMSYFDWPYNEGRRNTDGSESA
                     TMLSFKTDKDSYTPGEKMVVT"
BASE COUNT          677 a          634 c          823 g          673 t
ORIGIN      
        1 cggttaaagg cggaccgatt ggggaaactc gtgcgcctca agcccgatgt gccgggacga
       61 tgggctttcg agaataaccg gacgttggta ttcaagccgg agaaaggctt tgagcgaaac
      121 acctcttatc aggtgaacgc cgatttgtcc gaatggtttg aggcggaagg taaggataag
      181 cggttcgctt tcggttttac cacgctccct ttagctcttc gggggaatct ggagtcgatg
      241 gatatcaaca agaaaaacga gaatgggtac gatctgacag ccgtgctttt cacgccggat
      301 aaggaatctc cggggaccgt ggagtcgttg gtggatttct cggagaaggt agacgctact
      361 tggcaacaca gcccggatgg gaagaaacat gaggtaacct tgaccaatgt tcccgccggg
      421 atgaaggggg aacggatact taggctttcc gtctcttcga ataaactagg cgtggaaaag
      481 gccgatgtag tgacggtgag cattccggat cagaatgatt tctcggtgta cgacgtggta
      541 tatgtatctg agccggaatg ctacgtggag gtcgctttca cgaaattatt ggactcggcc
      601 caagatatga gaggcttggc ttttatcgcc ggaaatacct cggagaccgt aaacgtggat
      661 ggcaacaagc tacgcctata tccggacgcc gacttgcggg agaagggtgc gatgaacatc
      721 catctgaacc aaggcatccg cagtaagagc ggcttgaacc taaaagaggc cgtcgtgcgt
      781 caagtggtag ccaacgagca gaaacctaac gtccgtttta tcgggaaagg agtgatcatc
      841 ccgcaatcca cgcaattatc cgttcctttc caagcgattt atttgcgagg ggttacggtg
      901 agcgttatca agatattgga gcagaatatc ggtcagttcc tgcaatcgaa caacttggat
      961 gagtccgggg agttaatgcg tgtcgggcgc ttgatcgccc gtaagacgat cttcttggat
     1021 gaagagggtc ttgatttatc ccggtggaat accttcgcga tcgatttgaa acgattgatc
     1081 gagccggaac cgggcgctat ctaccgtctg gagctttcgt ttgaccgttc tttgtctgtt
     1141 tatccttgcg ggaatgatac ggtggtcctc tcgaaggaac agatcttggc ctcggatgag
     1201 atccgtttca aggaagagtc cgcccgtttt gacgagggag ggtattacta ttatcgccag
     1261 tatgattggt ctgattataa ttgggagaaa cgggatgatc cttgctcgga cagttattat
     1321 tttaataagg tggagggaaa gaatgtcttg gctactaatt taggactggt cgccttgatg
     1381 gggcaggata atgatatgac cgtgttggtg cataacatac agagtacgga gccggagcga
     1441 ggagttacgg ttaccgccta taattaccaa caccaagcgt tggcctcggg cacgaccgat
     1501 gacaagggac aggtacggct ggatctctcc tcgggacgtt cgttctacct gatcgcctca
     1561 cagggaaccc aacgttccta tctgcgggtg gataacggat cggctctctc gctcagctcg
     1621 ttcgatgtat cgggcgaggt cgtccagaaa gggatcaagg gctttatcta tggtgagcga
     1681 ggcgtatggc gtccgggtga tacgttgcat ctgggcttta tgctgaacga ccgggcgaag
     1741 caattgccgg cagagcatcc ggtggtgatg gagctgtaca acccgttagg gcaaatgtat
     1801 gctcgtaaga cgcagacccg tggcgagctg gggctttacg ccttcgattt cgttaccgag
     1861 gcggatgccc ccacgggtgc gtggaatgtg aaggcacaag tgggtggggt ctctttctcg
     1921 aagcgcttac gcatcgagtc catcaagcca aaccgcctga agatcgcctt atccatgccg
     1981 gagaagacct tgttgcgagg tgagcctatg gatgcccgcc tgcatgtggt atggctgcaa
     2041 ggagctatcg cccgtaactt gaaatatgat atacaaggta cctttatcgc caccccgact
     2101 accttcgagg gctataaggg tttctatttc gacgatcctt cccgtgtatt taatacggaa
     2161 gagagtaagc tgatctccgg tgttaccaat gagcggggcg atgccacggt acaagcccgc
     2221 ttcgagctgg gttctaccgc tcccggaatg ttgctggcaa acctagtgac ccgggtctat
     2281 gaggaatccg gtgatttcag tatcgacgcg gaccggatgc tttactcgcc ttatcgccgg
     2341 tatgccggta tcaaatctcc gcagaaagag aaggaacaac taaataccgg agccaattat
     2401 acctacgagg tcgcttctgt tgattattta gggaaaccgc aagcgaatac ggaattagac
     2461 gtgaaagtat ataaagtcta ttggtattgg tggtgggact ccaacagtag cggtctggcc
     2521 aattacgtat cggattcctt caataagccg gtaaagacat ttaccgtccg tacggatggg
     2581 gacggccggg gtacgttcca gctctctttc ccggataagg agtggggaac gtatttcatc
     2641 tccgtgaaag ataaggagag caagcactct acgggagtga tgagttattt cgactggcct
     2701 tataatgagg gccgacgtaa caccgatggc agcgagtccg ccacgatgct tagtttcaag
     2761 accgataagg atagttatac gcccggcgag aagatggtag tcacctt
//
LOCUS       DBMDTB010000202         2801 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_8012_length_2801_cov_8.125556, whole genome shotgun sequence.
ACCESSION   DBMDTB010000202 DBMDTB010000000
VERSION     DBMDTB010000202.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 2801)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 2801)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2801
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_8012_length_2801_cov_8.125556"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..770)
                     /locus_tag="ACZPB4_16865"
     CDS             complement(<1..770)
                     /locus_tag="ACZPB4_16865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase
                     domain-containing protein"
                     /protein_id="HIR1099922.1"
                     /translation="MKYFTRLIRWISSQEHLYFLFALLFIIPNCVFFFTEPLPVTVGI
                     ASLLIPLAFWMCVLLVARKPGIVVWCLLPKVILDGGQLVLLYLFGQSVIAVDMYLNLT
                     SSNASEASELLGNIILVIGCVFFFYTLPTLVLACRSIRQKEKLRNPFRKKWAKISLGM
                     FVVGLLLCFLSPSQDHRFSWKDDVYPANALYNLYFAINKAERNSKYHITSADFKFDAT
                     KPEQAEGKREIYVLVVGETSRAMEWSLYGYERKTTPRM"
     gene            complement(907..2580)
                     /locus_tag="ACZPB4_16870"
     CDS             complement(907..2580)
                     /locus_tag="ACZPB4_16870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008772433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/glycine:cation symporter family protein"
                     /protein_id="HIR1099923.1"
                     /translation="MQELNNLLSLIDAHFGGSQWFVFLLLGTGLFFTVYLRFPQLRFF
                     GHAIKVVRGKYDNKQDIGDTSHFQALATALSGTVGTGNIAGVALAIHLGGPSALFWML
                     MTAFLGMTTKMVEVTLSHKYREQTEDGTISGGPMYYMKHRLHMRWLAGLFAVATIFSS
                     FGTGSLPQVNSISNAMFSAFGIQQYITGAVLSVLLGLIVIGGIKRIAQVTEKLVPFMA
                     VVYLLGAFSILAYNYQHILPSFISVFSNIFSGTAATGGFLGATVVWAFNRGVNRGLFS
                     NEAGQGSAPIAHAAAKTEEPVSEGMVALLEPFIDTIVICSITGLVLLSSGTWLKKFEN
                     KFQQADTVVLSGAYHESDPDGKSAVSEHVLGNKPLPFYTGSLEVRNGQILNTDITLLH
                     ARSFADSVRVKEGKEVLFSGTLSVRDGRIELPMNKERAVYLTGKSLLHSAPLSTEAFK
                     KGFLGDWGQFIIPFSLLLFAFSTTIAWSYYGDRAVTYLWGTKYVRIYHVIYIVGFFLA
                     SFTDTTIVWTLSGITVALMTLPNLIGILLLHKEVKSSVNEYWRRMKEKL"
BASE COUNT          882 a          729 c          551 g          639 t
ORIGIN      
        1 tccatacggg gagtcgtctt gcgctcgtat ccgtaaaggc tccattccat agcacgggag
       61 gtctctccca ctaccaagac gtagatctcc cgttttccct ccgcttgctc cggcttagtg
      121 gcgtcgaact taaagtcggc ggaagtaata tgatacttgc tgttcctctc cgccttattt
      181 atggcgaaat ataaattgta tagggcgtta gccggatata catcgtcctt ccatgagaac
      241 cggtgatctt gcgaaggaga caggaagcaa aggagcaaac ccacgacaaa catgcctagg
      301 ctgatcttgg cccatttctt ccggaaagga tttcgcagtt tctctttctg ccgtatcgaa
      361 cgacaagcga gcaccagcgt aggtaatgta tagaaaaaga atacgcaacc gatcaccaga
      421 atgatattcc ccaataactc actagcctcg gaagcgttcg agctggtaag gttcaaatac
      481 atatcaaccg ctatcacgga ctgtccgaaa agatacagaa gcaccaactg ccccccatct
      541 aatataacct tcggcaacag gcaccaaacc acgatccccg gtttacgggc cactaataaa
      601 acacacatcc aaaaggccaa aggtatcagc aacgaggcga taccgaccgt gacgggaagc
      661 ggttccgtaa aaaagaacac acagtttggg atgataaata acagggcaaa taagaaatat
      721 aaatgctcct gtgaagatat ccagcgtatt aaccttgtaa aatacttcat tcaatcaaaa
      781 ctttgccaac tctcaatcat tactcttctc aactaatacc cagaacctga aattccggca
      841 attggcaaag ataggcgtta ttaaacacat acaaagcgta ttatacacaa aaaatgttat
      901 tgacattcat aacttctctt tcatccgtcg ccaatactca ttgacagagc ttttcacttc
      961 cttatgtaac agcaagatac caatcaagtt cgggagcgtc atcaaagcca cggtgatacc
     1021 ggataatgtc caaacaatag tagtatccgt gaacgaggcc aagaaaaatc cgacaatata
     1081 gattacgtgg taaatacgga catatttcgt tccccaaaga taggtcaccg cccgatcacc
     1141 gtagtaagac catgctatcg ttgtagaaaa cgcaaacaac aacagggaaa acggaataat
     1201 aaactgcccc caatccccta aaaaaccttt cttaaacgcc tccgtagaca agggggcgga
     1261 atgaagcagc gacttaccgg ttaaatacac cgcacgctct ttattcatag gtaattcgat
     1321 acgtccgtca cgtacagaga gcgtaccact aaacaacacc tccttccctt ccttgacccg
     1381 cacgctatcc gcaaaggaac gtgcgtgtag taacgttata tccgtattta ggatctgtcc
     1441 gttccggacc tccaaggagc ctgtataaaa aggcaggggc ttattcccta gtacatgctc
     1501 cgacactgcg gatttaccgt ccgggtccga ttcatgataa gcaccggaca agactaccgt
     1561 atccgcctgc tgaaacttat tctcaaactt tttcagccaa gtaccggatg acaatagaac
     1621 caagccggtt atcgaacaaa tcacgatcgt atcgatgaac ggctccaata aagcgaccat
     1681 accctcggat accggctctt ccgtcttggc tgccgcatga gcgatcggag cggaaccttg
     1741 ccccgcctca ttcgagaata atccacggtt cacacctcgg ttaaaagccc agacaaccgt
     1801 cgctcctaag aaaccacccg tagccgccgt accggaaaag atattcgaga aaacagagat
     1861 aaacgaaggt aggatatgct ggtaattata ggccaatatg ctgaaggcac cgagcagata
     1921 gacgaccgcc ataaaaggta ccaacttctc ggtaacctgc gctatacgct tgattccccc
     1981 gatcacgatc aatcccagca agaccgataa aaccgccccg gtaatatatt gctgaatacc
     2041 gaacgccgaa aacatggcgt tcgagatgct atttacctgt ggcagactac ccgtaccgaa
     2101 agaggagaaa atagtagcga ccgcaaaaag tcccgccaac caacgcatat gcaaacgatg
     2161 cttcatataa tacatcggac cgccggaaat cgtaccatct tccgtctgct cacgatactt
     2221 atgggaaagg gtgacctcta ccatcttggt agtcataccc aagaacgccg tcatcaacat
     2281 ccaaaacaag gcagaaggac cacctagatg tatggccaga gcgacaccgg ctatattacc
     2341 ggtccccacc gtgcccgaaa gagcagttgc caacgcttgg aaatgggagg tatctcctat
     2401 gtcttgctta ttgtcgtact tcccccgcac gaccttgatc gcatgcccga aaaagcgcaa
     2461 ttgcggaaac cgaagataga ccgtaaagaa caatccggtt cccagtaata gaaaaacaaa
     2521 ccattgtgat cctccaaaat gagcgtcaat aagagatagt aagttattca actcttgcat
     2581 catctgctta catttttaaa taatgatgcc gcaagttaag aataataaaa caaaaagcaa
     2641 ccttacaagc ctctattttt cattttagac tcataaaatt gcttttttat aatcaaaaag
     2701 atactaccac acaataaaat tatatttatc tcctatattt tctggaggat agcgataaac
     2761 tcatcattcg taatgtctag ctccggctct ttgtaattga c
//
LOCUS       DBMDTB010000203         2749 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_8178_length_2749_cov_10.522659, whole genome shotgun sequence.
ACCESSION   DBMDTB010000203 DBMDTB010000000
VERSION     DBMDTB010000203.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 2749)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 2749)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2749
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_8178_length_2749_cov_10.522659"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..207
                     /locus_tag="ACZPB4_16875"
     CDS             <1..207
                     /locus_tag="ACZPB4_16875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIR1099924.1"
                     /translation="GKTLSDYITDIRIGYAARMLVDTQRSIAEICYDCGFNNLSNFNR
                     IFKKKKNCSPKEFRDNYKKTKIIV"
     gene            572..>2749
                     /locus_tag="ACZPB4_16880"
     CDS             572..>2749
                     /locus_tag="ACZPB4_16880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SusC/RagA family TonB-linked outer membrane
                     protein"
                     /protein_id="HIR1099925.1"
                     /translation="MNSTIKKTTLFLGACMAFQLGGIPQMLAAPSTSMEVMQQTKRIT
                     GTVKDATGMEVIGANVIVKGTTNGVITDLDGKFSLEAAPGSIIEISYIGYMTQEIPVT
                     AQTSDLQITLKEDSQSLDEVVVVGYGVQKKKLVTGATLQVKGENIQKLNTTNPLGALQ
                     SQSPGVNIVANSGQPGKSFDINIRGAGTNGSTTPLYIIDGVEGDINSLSPADIESLDV
                     LKDAASAAIYGSRAANGVVLITTKQGKQGKLQVSYDGYVGFQNVYKMPDLLNAKEYMA
                     VMDQLNFNTGNQPYTWTNYMSQEQYNRYMSGEDEGTNWLDAIRNKNAITTSHSLNLAG
                     GTERSKFSTGVSYTKQEGTLGKPVASDYQRFTVRMNSEHILWKEGDLDIITFGENLYY
                     NHNESSGISEGNQYGNDISWMLRANPLVPIYNENGDYYMYDDLNKAGWFNYNSYTSNP
                     IAAMVNSSRGNNKSKNYGLTMVGYLKVQPIKGLVYKGQVSYKQNSSSYRGYSPAYKLT
                     STDQKLTNEVTQNMMTGWDWQIENTLSYTFNIEKHNFDVLVGQSFKKSGFGMGEYLEA
                     TANDLLFSDWDRAYISNSMASQPTSAKGYPTGDNALASFFGRINYNFNEKYMASVILR
                     TDGSSNFARGKRWGTFPSVSAGWVVSNEDFMENTHDWMDFLKIRASWGQNGNCNIDNF
                     QYFSTVAFDHLGQYSFGNNKGTATQGGYASIMPNEDVTWETSEQ"
BASE COUNT          832 a          656 c          620 g          641 t
ORIGIN      
        1 gggaagaccc tctccgacta tatcaccgat atccgtatcg gttacgccgc ccgcatgctg
       61 gtggacacgc aacgatccat cgcggagatt tgttatgact gcggcttcaa taacctctcg
      121 aacttcaacc gtatctttaa gaaaaagaaa aactgctctc ccaaagagtt ccgggataac
      181 tacaaaaaga caaaaatcat tgtataagag acctttttaa cagggataaa tacatatccc
      241 cccctatttc tatacaaaat ccccccttct cttttccttc acacatctat ctttgcgacc
      301 agtcacaaag gctttcatgc ctacggctac cccatcgatg tgttaaaaat acactccggc
      361 aaaaaagtat tattcttgga taaaatagta tttgaacgca cttgggatcc gacgtaattt
      421 tgcgacagaa attaacaata catattaaca acaaaaaaca attgcctatg aggaaggacc
      481 gaaaatctaa tgtttttagc agttaaccgc taatgaccct attgagtaaa tgaattttag
      541 tttagcctta tatgatttaa tgtaaaaaat aatgaattca acaattaaga aaacgacgct
      601 gtttttaggc gcatgtatgg ccttccagct aggtggcata ccacaaatgt tagccgcccc
      661 tagtacttcg atggaagtca tgcaacaaac aaaaagaatc actggtaccg tgaaagacgc
      721 aacaggaatg gaagtcatcg gtgccaatgt tatcgtaaag ggaacgacaa acggagtgat
      781 aaccgatttg gatggtaagt tcagcttaga ggccgccccc ggctctatca tagagatctc
      841 ctacattggt tatatgaccc aagagattcc cgtaaccgcc caaacatccg acttacagat
      901 caccttgaaa gaggactcac agagtttgga cgaggtagtg gtagtaggtt atggtgtaca
      961 aaagaaaaag ttggtgacag gtgcgaccct tcaagtaaag ggagagaata tccaaaaatt
     1021 aaacacgaca aacccgctag gtgccttgca gagccaaagc ccgggcgtca atatcgtagc
     1081 gaactccggc cagccgggta agagtttcga tatcaacatt cgtggtgccg gaacgaacgg
     1141 cagcacgact ccgctataca ttattgatgg cgtcgaaggc gacatcaatt ccttaagtcc
     1201 cgccgatatc gagagcttgg acgtattgaa agatgccgct tccgctgcga tctacggttc
     1261 acgtgcggcc aacggtgttg tattgatcac gacaaagcag ggcaaacagg gtaaattaca
     1321 ggttagttac gacggctatg taggtttcca gaacgtatac aaaatgccgg acttgctgaa
     1381 tgcaaaggaa tacatggcag tcatggacca actgaacttc aacacgggta accaacctta
     1441 cacgtggacg aattacatgt cacaagaaca gtacaaccgt tacatgagcg gcgaggatga
     1501 gggtaccaac tggcttgacg caatccgcaa caagaacgcc atcactacca gccactcctt
     1561 gaacttggcc ggtggtacgg aacgctccaa attctccaca ggtgtatcct atacgaaaca
     1621 ggaaggtacg ctaggcaagc cggtcgcttc cgactaccaa cgtttcacgg ttcgcatgaa
     1681 ctctgaacat attttgtgga aagagggtga cttggatatc atcacattcg gagaaaacct
     1741 gtactataat cataatgaat cttccggtat ctccgagggt aatcaatacg gtaacgacat
     1801 ctcttggatg ttacgtgcca acccgctggt tcctatctat aacgagaacg gggattacta
     1861 tatgtatgac gacttgaaca aggccggttg gttcaactac aactcttata cgagtaaccc
     1921 aatcgccgca atggtcaact cctcccgtgg aaacaacaag agcaaaaact acggattaac
     1981 tatggttggc tacttgaagg tacaaccaat caagggactc gtctataaag gacaggtcag
     2041 ctacaaacag aactccagct cttaccgtgg ctacagtccg gcttataaac taacctctac
     2101 cgatcagaaa ctaaccaatg aggttaccca gaacatgatg actggttggg actggcagat
     2161 cgagaatacg cttagctaca ccttcaacat cgagaaacac aacttcgatg tattagtcgg
     2221 tcaatccttc aagaagagcg gtttcggtat gggtgagtat ctggaggcaa cggcgaacga
     2281 ccttctgttc tccgactggg accgggctta tatcagcaat agcatggctt ctcagcctac
     2341 ctcagccaaa ggatatccga caggggataa cgccttggcg tcattcttcg gacgtatcaa
     2401 ctataacttc aacgagaaat acatggctag cgtgatctta cgtacggatg gttcctcgaa
     2461 cttcgcccgt ggtaaacgct ggggtacgtt cccttccgta tcggctggtt gggtcgtgag
     2521 caatgaagat ttcatggaaa acacgcacga ctggatggac ttcttgaaga tccgtgccag
     2581 ctggggtcag aacggtaact gtaatatcga taacttccaa tatttctcga ccgtagcgtt
     2641 cgaccacctc ggacaatatt ccttcggcaa caacaagggt acggccacgc aaggcggtta
     2701 tgccagcatc atgccgaacg aggacgtgac atgggagact tccgagcag
//
LOCUS       DBMDTB010000204         2710 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_8337_length_2710_cov_8.808739, whole genome shotgun sequence.
ACCESSION   DBMDTB010000204 DBMDTB010000000
VERSION     DBMDTB010000204.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 2710)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 2710)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2710
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_8337_length_2710_cov_8.808739"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..110
                     /locus_tag="ACZPB4_16885"
     CDS             <1..110
                     /locus_tag="ACZPB4_16885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HIR1099926.1"
                     /translation="VNSIPHTVLVDKDGTIIAKNLHGEEIDAKLQEILK"
     gene            129..575
                     /locus_tag="ACZPB4_16890"
     CDS             129..575
                     /locus_tag="ACZPB4_16890"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005855911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004601 - peroxidase activity [Evidence
                     IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OsmC family protein"
                     /protein_id="HIR1099927.1"
                     /translation="MSAQITLNWTKDSTFETLLDGHKVTIDTTAENGGNNEGPRPKAL
                     MLVALAGCSAMDVISLFLKMRVRFDKISIDVTAETSDTIPMVYTAFHATYHIDGNIGD
                     AAKIEKAIRLSQEKYCGVGLMMKKIGPITYDILLNGEPLKPQKHED"
     gene            565..2520
                     /locus_tag="ACZPB4_16895"
     CDS             565..2520
                     /locus_tag="ACZPB4_16895"
                     /EC_number="3.1.6.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl/aryl-sulfatase"
                     /protein_id="HIR1099928.1"
                     /translation="MKIRKQFLLLFISTSHLFVYAQNTEPSMFTKEANEQVVKSLPFE
                     NKQDFEDATRGFIATIDEPSIIDETGKEVYGLTVWDFLRQEAPASANPSLWRQGQLNR
                     IHGLFEVLPGKIYQIRGFDLANMTFIRSDNGWIVIDVLLSKETALAGYNLLKKHVENL
                     PVKAVIYTHPHVDHFAGIDAILENAPNKPETIEIIGPKGFFEDAVSENLMAGVAMGRR
                     ATYMYGRSLPKNEKGNIGTGLGQTTAAGTTGLVPPTREISEEGETLRIDGVEIVFMSV
                     PGAEAPSEIMMYFPGMKAFCVAEEINRTLHNLLTLRGAKVRNGQLWSKYIDRAITECG
                     DQVEVSFSTHHWPTWGNKNIVAYWEKQRDLYRYLHDQTLHLANQGYTPREIAEMIKLP
                     SSIANEFANRGYYGTVSHNVKAQYQMYFGWFDGIPAHLNPLPPVEEGKKYVEAIGGED
                     EIMKKAREAYNQGEYRWTATLLNHLVFANPKHKPARQLLADTYAQLGYQAESGPWRNF
                     YLTGAMELTEGIAGKGKSNSNRARMSQNLSPEMLFDLLAIQINGEKAADKDLIINIIL
                     TDTNEQATLILKNGALSNRIGRLHPAPTVTLEGDKQVIYASLMQPENIAANLQAHKLS
                     VTGKLESLKELFSTLEAPDAYFNIIEP"
BASE COUNT          826 a          647 c          624 g          613 t
ORIGIN      
        1 gggtaaacag catccctcac accgtattgg tggataagga cggaacgatc atcgccaaga
       61 acctacatgg cgaggagatc gacgctaaac ttcaagaaat attgaaataa taataacaat
      121 aacacgatat gtccgcccaa atcacgttaa actggacgaa ggactcgact ttcgagacct
      181 tgctggacgg ccataaggtt acgatcgaca caacagccga gaacgggggt aataatgaag
      241 gcccccgtcc caaggcttta atgctggtcg ccttggccgg atgcagcgca atggacgtaa
      301 tctccctttt ccttaaaatg agagtacgtt tcgacaaaat ctctatcgac gtaaccgcag
      361 agacttcgga tacgatcccg atggtatata ccgcattcca cgctacatac catatcgacg
      421 ggaacatcgg ggacgccgcc aaaatagaga aagcgattcg cctttcacag gaaaaatact
      481 gtggcgtagg acttatgatg aaaaagatag gcccgattac ctacgatatc ttactgaacg
      541 gcgaaccgct taaaccacaa aaacatgaag attagaaaac agttcttact tttatttatc
      601 tctaccagtc acttgttcgt atatgcgcaa aacacggaac cttcaatgtt tacgaaagag
      661 gctaacgaac aagtggtgaa atcactccca tttgaaaaca aacaagattt tgaagacgct
      721 acccgtggct ttatcgccac gatagacgaa ccttccatta tcgacgagac aggaaaagag
      781 gtgtatggat taactgtctg ggatttcctg cgtcaagagg ctccggcatc cgccaaccct
      841 agtctttggc gacaagggca actcaaccgc atacacggct tatttgaggt attacccggt
      901 aaaatatacc agatacgagg attcgacctc gcaaatatga cgtttatccg tagtgataac
      961 ggttggatcg tcatagatgt attgctctcg aaagagacgg ccctagcagg ttataatctt
     1021 ctgaagaaac atgtagaaaa tcttccggtc aaggcggtta tctatacgca tcctcatgtg
     1081 gaccatttcg cgggaataga cgctatattg gagaacgccc ccaataagcc cgaaacgatc
     1141 gagatcattg gccccaaggg tttctttgaa gatgccgtca gcgagaacct gatggcgggt
     1201 gtagccatgg ggcgaagagc gacctatatg tatggccgca gtctacctaa aaatgagaaa
     1261 ggaaatatag gtactggttt aggacaaact accgcggcag gaactacggg cttggtccct
     1321 cctacccgtg agatatccga ggagggcgag actttacgaa ttgatggtgt cgagatcgta
     1381 ttcatgtccg tacccggcgc cgaggctccc tcggaaatca tgatgtactt ccctgggatg
     1441 aaagctttct gcgtagccga ggaaatcaac cgtaccctgc acaacctgct gaccttacga
     1501 ggggcgaagg tccggaacgg ccaattatgg agcaaatata tcgaccgggc gatcacggag
     1561 tgcggcgatc aggtagaggt atccttctct acccaccatt ggccgacttg gggcaataag
     1621 aacatcgtcg cttactggga aaagcagcgg gatctatatc gctacttaca cgaccagaca
     1681 cttcacctcg ccaatcaagg atatacacct cgagaaatag cagagatgat taaattacca
     1741 agctctatcg ccaacgagtt cgccaaccgg ggatattatg gaaccgttag ccataatgta
     1801 aaagcccaat atcaaatgta tttcggctgg ttcgacggca tccccgccca tctgaaccca
     1861 ctcccgccgg tagaagaagg taaaaaatac gtagaggcta tcggaggaga ggacgagata
     1921 atgaaaaagg cacgagaggc atacaatcaa ggagaatacc gttggacggc tactttgctg
     1981 aaccatctcg ttttcgctaa tccaaagcat aaacccgccc gccaattact tgcggacacg
     2041 tacgctcaat tgggctacca agcggaaagc ggtccgtggc gtaatttcta cctgaccgga
     2101 gctatggaac tgaccgaagg catcgctggt aaaggcaagt ccaactcaaa ccgggcacgt
     2161 atgtcccaga acctaagtcc cgaaatgcta ttcgatttgc tcgctatcca aataaatgga
     2221 gaaaaagcgg ccgataaaga cttaataata aatattatct taaccgatac gaacgaacag
     2281 gccaccttga tcttaaagaa cggcgcctta tcgaaccgta tcggcaggct ccatccggcc
     2341 cctaccgtaa ctttggaagg agacaaacaa gtcatttacg caagtctcat gcagccggag
     2401 aatatagcgg caaatctgca agcccataag ttatcggtaa ccgggaaact tgaaagccta
     2461 aaagagctat tctccacttt agaggctccg gacgcttatt ttaatatcat cgagccttaa
     2521 acctttcccg cctcttgcat ggctggatta aaaaatttat ctttgtgcga tctttagaga
     2581 aagcgatatt actataaaat tagcataaag ttttattaca ctttaatata ataaattagc
     2641 gattatgatt tattcacatg aagttcaaca catgtgtgtt gtaaagaagg gagctaacca
     2701 ccagtgcgct
//
LOCUS       DBMDTB010000205         2652 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_8586_length_2652_cov_9.637397, whole genome shotgun sequence.
ACCESSION   DBMDTB010000205 DBMDTB010000000
VERSION     DBMDTB010000205.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 2652)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 2652)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2652
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_8586_length_2652_cov_9.637397"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..560)
                     /locus_tag="ACZPB4_16900"
     CDS             complement(<1..560)
                     /locus_tag="ACZPB4_16900"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008155644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIR1099929.1"
                     /translation="MIKIEGLSKFFRTEEVETIALNKVSLEVKDGEFVAVMGPSGCGK
                     STLLNILGLLDNPSEGNYYLGDQEVGHLKEKERTQVRKGNIGFVFQSFNLIDELNVFE
                     NVELPLTYLKIKASERKQMVTDILKRMNISHRAAHFPQQLSGGQQQRVAIARAVVSNP
                     KIILADEPTGNLDSKNGAEVMQLLTEL"
     gene            complement(806..1246)
                     /locus_tag="ACZPB4_16905"
     CDS             complement(806..1246)
                     /locus_tag="ACZPB4_16905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5024 domain-containing protein"
                     /protein_id="HIR1099930.1"
                     /translation="MKASKCFWVALCLLVGNFSTELWAQKNLEAVVQKCKADKTIDKS
                     VVTNKDPKTKKVYKIVSSFVVEGHAALQQEIKSAFERDKEEAYQVIENENDGVVSWFI
                     RFSKGKNTVSYSINVDEEELLLTVIENFDMPEEKDIEIRSSSDM"
     gene            complement(1274..1861)
                     /locus_tag="ACZPB4_16910"
     CDS             complement(1274..1861)
                     /locus_tag="ACZPB4_16910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099931.1"
                     /translation="MKTEEYKSIEDLLDRFFEGRTSNEEERVLYEFFARPDIPAHLER
                     YREVFGYFESGIALDFSETPELRLPAKESSNKRKIGWAIAVCVAASLLLFLVNTVFMN
                     QNASFNPYEGSYIVRNGVVMTDIKKIQPELEVISRAAEAMEKNADQLLRNADEIAYLP
                     ERMNKRFEKKRETLLRNIPDTQVRKEVYKILELDK"
     gene            complement(1858..2358)
                     /locus_tag="ACZPB4_16915"
     CDS             complement(1858..2358)
                     /locus_tag="ACZPB4_16915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008774275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HIR1099932.1"
                     /translation="MEQEQFKKEILPLREKLFLYARRLLDNPEDAEDVMQEVFLKLWY
                     MRGELDYYNNVMALSVQITKHLCLNRMKVRERTEGEAGEQFFICDASTPYTQLEQKDS
                     LEHVMRLINKLPGLQQTILRMKHVDGFEVEEIAGLTGSTPEAVRMNLSRARKRVREQF
                     FKMQTL"
BASE COUNT          709 a          688 c          479 g          776 t
ORIGIN      
        1 agctcggtga gcagctgcat aacctcggca ccgttcttgg aatccaagtt acccgttggc
       61 tcatcggcca agattatctt cgggttggaa actaccgcac gggcgatcgc tacacgctgt
      121 tgctgacctc cggagagttg ctgagggaag tgagccgcac ggtggctgat attcattcgt
      181 ttcaagatat ccgttaccat ctgtttacgc tccgacgcct tgatctttag ataagtcaac
      241 ggcagctcca cgttctcaaa aacgttcaac tcgtctatca agttgaagct ctggaacacg
      301 aaaccgatgt ttcccttacg gacctgcgta cgctctttct ctttcaagtg tcctacctct
      361 tggtcgccca agtaataatt tccctcggaa gggttatcca gcaaacccag aatattcaac
      421 aacgtagact taccgcaacc ggaaggtccc atgacagcga cgaactcgcc atcttttacc
      481 tccaaagaaa ccttattcaa cgcaattgtc tcaacctctt ccgtacggaa aaacttactt
      541 aaaccttcga tcttaatcat gactgtattt gttttaattg ttatctaact gtttaattta
      601 ccatatctaa ttcaaatagt gtgccaaact aactaaatat ttaattatca aacaagtagt
      661 attttacttt ccaaaacaga ctgtccaatt atttgacagt ggtgtacaaa atttagacac
      721 tactatccaa tatcttgaca taaagaaaca cctcccagct tcacagatga gaggtgctat
      781 tgttgactta tctacatagt aaaacctaca tgtcactact tgatcttatc tctatatctt
      841 tttcctccgg catgtcgaag ttctcaatga ctgtcaagag aagctcctct tcatcaacat
      901 ttatagaata agaaactgta tttttaccct tcgagaaacg gataaaccaa ctaaccaccc
      961 catcgttctc attctcgatc acttgataag cctcttcctt gtcccgctca aaagcggatt
     1021 taatttcttg ttgtaatgcg gcgtggccct ccacgacgaa agaagagact atcttatata
     1081 cctttttagt tttcggatct ttattcgtta ctacgctttt atcgatcgtc ttatccgctt
     1141 tacatttctg cacgacagcc tccaaattct tctgtgccca taactctgta ctgaaatttc
     1201 ccaccaaaag gcataatgcc acccaaaaac atttacttgc tttcataact tcttttgttt
     1261 attagttaat ttactattta tccaattcca agatcttata aacctcctta cgtacctgag
     1321 tatccggaat attcctcagt agagtctccc gtttcttctc gaaccgctta ttcatccttt
     1381 ccggcaaata agctatttca tccgcatttc ttaagagctg atccgcattc ttctccatcg
     1441 cttccgccgc tcgggatatg acctccaatt cgggttgtat cttctttata tctgtcatta
     1501 cgacaccatt gcgcacgatg tagcttccct cataagggtt aaaagaagca ttttgattca
     1561 taaagaccgt attcaccaaa aataacaaaa gagaagccgc cacgcaaaca gcgatcgccc
     1621 atcctatttt tcgcttatta gaagattcct tagcgggtag cctcaattcc ggagtctcgc
     1681 taaaatccaa ggcaatgcca ctctcgaaat atccgaatac ctcccgataa cgttccagat
     1741 gggcgggaat atccggacgg gcgaagaact catacaacac tcgctcctcc tcgttcgagg
     1801 tccggccctc gaagaagcgg tctaataaat cctctataga cttgtattcc tctgttttca
     1861 taacgtctgc attttaaaga attgctctct cacccgttta cgggcacggg aaagattcat
     1921 acgtaccgcc tcgggggtac ttccggtcaa cccggcgatt tcctctacct cgaaaccatc
     1981 cacgtgtttc atgcgaagaa tggtctgttg aagtcccggt agtttattga taagccgcat
     2041 tacatgctcc aaactgtctt tttgttccag ctgggtataa ggcgtggagg catcgcagat
     2101 aaagaattgt tcgcccgcct caccttccgt gcgttcacgg actttcatcc ggttcaggca
     2161 aaggtgcttg gtgatttgta cggacaaggc cattacatta ttataatagt ccaactcgcc
     2221 acgcatatac cacagcttca aaaagacttc ctgcatgaca tcctcggcat cctccgggtt
     2281 atccagcagc cttctcgcgt aaaggaatag tttctcccgc aaaggcaata tctctttttt
     2341 aaactgttct tgttccattc tatcttaatg acaatcgaga aaagaaaacg taacatggtt
     2401 ggagaaaata aattcaaggt ctttgtcatt ctagtattat agtcgtgcca cccttatggc
     2461 acgataatgc cacggcgatg gcacgacgat gccatagcaa tggcacaacg atgccacgct
     2521 ggtggcacag ccgtgccact ataacggcac cggcttggca ctgtaagtta ttactaaata
     2581 gccctataca tcacagatac ggatacactt ctccaaggaa gcgatcttgt cttcttgggc
     2641 ggggacgaac tc
//
LOCUS       DBMDTB010000206         2571 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_8920_length_2571_cov_11.575304, whole genome shotgun sequence.
ACCESSION   DBMDTB010000206 DBMDTB010000000
VERSION     DBMDTB010000206.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 2571)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 2571)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2571
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_8920_length_2571_cov_11.575304"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..972
                     /locus_tag="ACZPB4_16920"
     CDS             <1..972
                     /locus_tag="ACZPB4_16920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009016496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-bladed beta-propeller"
                     /protein_id="HIR1099933.1"
                     /translation="AIGKNLIILRNKNGQDGDIFIFDRTGKGQRKINRSGQGSQEYTN
                     IGSIALDEEKGELFINNYYSSQFIVYDLSGNFKRTLKYDKDFNFNSGKIYNFDQDNLI
                     CYDEIGNYKNLRKSAFWLLSKQDGSIVKEIELPYEHKISPFLSKGGWAAGPRNTELIS
                     QNGSWVLVEPSTDTIYSYSQDHSIKPFIVRTPPIRSMAPEVFLYPSILTDRYYFMQTT
                     KKQWDFEKETGFPRTDLVYDKQEDAIFECVVYNNDFVDQTPVNMWYEHGILKIINNDG
                     IAFIKKLEANELVEAYEKGKLKGRLNEIAAGLNEESNPVIMVAKYKE"
     gene            1256..>2571
                     /locus_tag="ACZPB4_16925"
     CDS             1256..>2571
                     /locus_tag="ACZPB4_16925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HIR1099934.1"
                     /translation="MNQTIYPIGIQNFEKIRKDGYLYIDKTALVYQLVTTGQYYFLSR
                     PRRFGKSLLLSTLEAYFQGKKELFEGLAMEKLEKDWKEYPILHFDLNISQYDSPDSLY
                     KILNDILSRYEDEYGTRPSEVTLPLRFAGIIDRAYRKTGQRAVILIDEYDKPLLQNLH
                     DEEMQNRLRNMLKPFYGVLKTMDRAIRFALLTGVTKFGKISVFSDLNNLMDLSMDNRY
                     VEICGITEKEIHAYLEDEVKELADTQMTTYEETCLKLKQRYDGYHFTAKSEGIYNPFS
                     LLNTFAKMEFGDYWFETGTPSYLVELLKHTHYDLYEMANTETDADVLNSIDSASNNPI
                     PVIYQSGYLTIKGYDPEFGIYRLGFPNKEVEEGFVKYLLPFYTSIQASKTPFEIGQFV
                     REIRSGNYDAFFHRLQSFFADTPYEVIAGQKPERDTELHYRNVLFIV"
BASE COUNT          787 a          609 c          556 g          619 t
ORIGIN      
        1 gccatcggca aaaatctcat aatccttaga aacaagaacg gacaagacgg agatatattt
       61 atcttcgacc ggaccggaaa aggccagaga aaaatcaacc gaagcggtca aggtagccaa
      121 gaatacacga atatcgggtc tattgccctc gatgaggaga aaggtgagtt gtttatcaac
      181 aactactact cgagccagtt tatcgtatac gatctgtccg gaaactttaa gcgaacttta
      241 aagtacgata aagattttaa tttcaatagc gggaagatat acaatttcga tcaagacaac
      301 ttaatctgct acgatgagat tggtaattat aaaaatctga gaaaaagcgc attttggctc
      361 ctgtccaaac aagacgggag cattgtcaag gaaatcgaac tcccttatga gcataagata
      421 tcaccgtttt tatcgaaagg aggttgggcc gcgggacctc gtaataccga attaatttcc
      481 caaaatggaa gttgggtttt agtagagcca tctacagata cgatttatag ttattcgcaa
      541 gatcactcta tcaaaccctt tatcgtaagg actccaccta tccgctctat ggccccggaa
      601 gtatttcttt atccaagtat tcttaccgac cggtattatt tcatgcaaac aacaaagaaa
      661 caatgggatt ttgagaaaga aaccggattc cccagaaccg acttggtata tgataaacaa
      721 gaggacgcta tctttgagtg tgtcgtatat aataacgatt tcgtagatca gacacccgtt
      781 aatatgtggt acgaacacgg aatactaaag atcatcaata acgatgggat cgctttcata
      841 aagaaactag aagccaatga gttggtggaa gcctacgaga aaggtaagct gaaaggccga
      901 ttgaatgaga tcgcagcggg attgaatgag gaatccaacc ccgtgattat ggtggctaag
      961 tataaggagt aaaaaacttc ttacttattg tctatttttc cagacttgtt ttttattcgt
     1021 acatgttttt cggaaaacac gtacgtgaat tcccaaaaac acgtacgtga atccgtgaaa
     1081 acatgtacgt gtttttacgg aaatccgaca agcatattta tctatcttat tatcagcgaa
     1141 ttgtaaatcg acttcatagt aagatattat tgttgaaaat ttacttctaa agatacggtt
     1201 cctctcctat attttatgta actttgctta taagtcgcat aaaatatagg acgatatgaa
     1261 ccagacaatt tatcccatcg gcatacagaa cttcgagaaa attcgcaagg acggctatct
     1321 ctatattgac aagacagcct tggtctatca attggttact accggacagt attacttcct
     1381 cagccgcccc cgacgcttcg ggaaaagcct gttgctgtcc acgctggagg cctatttcca
     1441 agggaaaaag gagctgttcg agggactggc catggagaaa ctggaaaagg actggaaaga
     1501 atacccgatc ctccattttg acctgaatat ctcccaatac gactctccgg atagcttata
     1561 caagatatta aacgacatcc tgtcccggta cgaagacgaa tatgggacac gtccctcgga
     1621 agtgaccctg cccctccgtt tcgccggaat catcgaccgg gcctaccgca aaaccggaca
     1681 aagggccgtg atcctgatag acgagtacga caagcccttg ctacagaact tgcacgacga
     1741 ggagatgcaa aaccggctcc ggaacatgct caaacccttc tacggcgtat tgaagaccat
     1801 ggatagggcc atccgcttcg ccctgctcac aggtgtgacc aagttcggca agataagcgt
     1861 gttcagcgac ctcaacaacc tcatggacct gtcgatggat aatcggtacg tcgagatatg
     1921 cggcatcaca gagaaagaga tacatgccta tctggaagac gaagtgaagg aactggctga
     1981 tacccaaatg acgacctacg aggaaacctg cctaaaactc aagcaacgct atgacggata
     2041 ccatttcacc gccaagtccg agggtatata caatccattc agcctattga ataccttcgc
     2101 taagatggaa ttcggagact actggttcga gaccggaaca ccctcctacc tcgtggagct
     2161 gctcaagcac acccattacg acctctacga gatggccaac acggaaaccg acgccgacgt
     2221 gctcaacagc atcgactccg cctcgaacaa tcccataccc gtcatctacc aaagcgggta
     2281 tcttaccatc aagggctatg atcctgagtt tggcatttat cgactgggtt tcccgaacaa
     2341 ggaggtggaa gaaggtttcg tcaaatacct acttcctttc tatacgagca tacaagcctc
     2401 taagaccccc ttcgagatcg gacagttcgt tcgggagata cggtctggca attacgacgc
     2461 cttcttccac cgcctccaaa gcttcttcgc cgacacaccc tacgaggtga tcgccgggca
     2521 aaagccggaa cgagacacgg agctgcatta ccggaacgtc ctcttcatcg t
//
LOCUS       DBMDTB010000207         2530 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_9090_length_2530_cov_12.337176, whole genome shotgun sequence.
ACCESSION   DBMDTB010000207 DBMDTB010000000
VERSION     DBMDTB010000207.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 2530)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 2530)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2530
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_9090_length_2530_cov_12.337176"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..1931)
                     /locus_tag="ACZPB4_16930"
     CDS             complement(<1..1931)
                     /locus_tag="ACZPB4_16930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004866 - endopeptidase inhibitor activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MG2 domain-containing protein"
                     /protein_id="HIR1099935.1"
                     /translation="MKIRAIILSALILCGISAVIMYSRAAQPQQKSSVITQAINDKNT
                     PMVIKNLILKMKEQMEVNDDQFPELIKEVENYTNSCADSASVAVLHSMLAEMYQNYYQ
                     RNQWTINQRTQLSGYIPEDIRVWTSNLFTDKIKEEIDLSLRPTALLQNTPVSKFKDIL
                     EIGKDSQTLRPTLYEFLAFRALDIQPTVQIYKDLIAFQNKEPNMKSVLLTELDYLRFL
                     YGDKRDKESFEAYMNALDELYRNLASQNYAAEILIAKLDLVSGSMFRYVSTQWDSIKA
                     EEVKLCEEGIKRYSGYPRTAILKNRLAQLEQPTLSASTNNTVYPGQQLGIKLEYKNVQ
                     KVIVQIYRSSKTPLQAAAHTSAKKSSGSTLGQLVNEKTFSLLLPNTYSQQNTTLHISM
                     DQPGLYECVVTVPGQQLKTINTVSVTRLAAIYRNLSGNKQEVMVTDYLSGKPVDGAIV
                     TYYGGQRRSLQELGTVKTDREGLATLPANSQVLAFQASRPGDTNAMLTNIYPMGSGHK
                     PEKNPVEVSIFTDRGLYRPGQTIFFKGLAYVKDSNDPHAVAGQTFTVTLYDANGKELA
                     QKKFTTNDFGSFNGEFSIPKQTLSGVFRLSTGQMSVYIHVEEYKRPTFQAYFLPIKGD
                     IAFGDSVTIQGKAATFSGVS"
     gene            complement(2019..2516)
                     /locus_tag="ACZPB4_16935"
     CDS             complement(2019..2516)
                     /locus_tag="ACZPB4_16935"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005858889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0046654 - tetrahydrofolate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HIR1099936.1"
                     /translation="MSTISIIAAIADKSAIGKNQQLLCHMPSDMKRFKELTTGHAVIM
                     GRKTFESLPVAPLPNRKNVVLTTMPEAGFVNCFACESMGAALDLCEKEDEIFIIGGAL
                     VYRQALRIADKMYITRIHHEFPDATSFFPVVNWDLWEETEREEYPADEKNPYPYTYIT
                     YVRKK"
BASE COUNT          615 a          575 c          601 g          739 t
ORIGIN      
        1 gacacgccgg aaaatgtagc cgccttgcct tgtatggtaa cggaatcgcc gaaagcgata
       61 tcgcccttga tcgggaggaa gtacgcttgg aaagtcgggc gtttgtattc ctctacatga
      121 atatatacgc tcatctgtcc ggtacttaac cggaagacgc cgcttagggt ctgtttgggg
      181 atggagaact cgccgttaaa agaaccgaag tcattagtcg tgaatttctt ctgggctagc
      241 tctttcccgt tagcgtcata caaagtcacc gtaaaagtct gtccggccac ggcatgcggg
      301 tcgttcgagt cttttacgta ggcgagacct ttgaagaaaa tggtttgtcc cggacggtaa
      361 agtccacggt ccgtaaagat cgagacttct accgggttct tttccggttt gtggccggaa
      421 cccatcgggt agatatttgt caacatagcg ttggtatctc ccggtctgct ggcttggaac
      481 gccaatactt gactgttcgc cggaagcgtg gccaagcctt cccggtctgt cttgacggta
      541 cccagttctt gcaagctacg acgctgacct ccgtaatagg taacgatagc cccatcaaca
      601 ggcttcccgc taagatagtc ggtaaccatg acctcttgtt tattaccgga aagattacga
      661 tagatcgcgg ccaatcgggt tacgctaacc gtattgatcg tctttagctg ttgtccgggt
      721 acggttacga cacattcata caatcccggt tgatccatag atatatgtaa ggtcgtattt
      781 tgctgcgaat aggtgttggg cagtagcaaa gagaatgtct tctcatttac gagttgtccc
      841 aaggtgctgc cacttgattt ttttgcggat gtatgggctg ccgcttgtaa aggtgttttc
      901 gagcttcgat agatttgtac gatgactttc tgtacattct tatattccag cttgatcccc
      961 agttgctgtc ccggataaac cgtattgttt gtagatgcgg ataaagtagg ttgttccaat
     1021 tgcgccaagc gattctttaa gatagccgtg cgagggtaac cggaataccg cttgataccc
     1081 tcctcgcata gtttcacctc ttccgctttg atagaatccc attgggtaga gacgtaacga
     1141 aacatactgc cgctaaccaa atccaatttg gcgattaaga tctcggctgc atagttttga
     1201 gaagctaagt tcctgtaaag ctcatccaat gcgttcatgt aagcctcaaa agactcttta
     1261 tcccttttat ccccgtaaag gaatcgtagg taatccaatt ccgtaaggag gaccgatttc
     1321 atattcggct ccttattttg aaaggcgatc aagtctttat agatctgtac ggtcggttgg
     1381 atgtccagtg cccggaaggc aaggaactca tagagggtcg gacgcagggt ttgcgagtcc
     1441 tttccgatct ccagaatatc cttgaacttg ctgacaggcg tattttgcaa taaggccgta
     1501 ggtcgcaatg ataaatcgat ctcttccttg atcttatccg tgaataagtt ggaagtccat
     1561 acccggatat cctccgggat ataaccgctt aattgggttc tttggttgat ggtccactgg
     1621 ttccgttggt agtaattctg atacatctcc gccagcatgg aatgtaatac cgccacggaa
     1681 gccgagtcgg cgcaactgtt ggtgtaattc tccacctcct tgatcagttc cgggaactga
     1741 tcatcgttta cctccatctg ttctttcatt ttaaggataa gattcttgat caccataggg
     1801 gtattcttat cgtttatagc ttgcgtgata acagaacttt tttgttgagg ctgggcggcc
     1861 cggctataca taataaccgc cgagatgccg caaagtatca gggcagataa aataattgct
     1921 cttatcttca tatcttttgg gttttataag tttaacaata aacctttcct atatagatac
     1981 aaagaaagag caaaaagttg taaaacgtac gttaatgttt attttttgcg cacgtaggtg
     2041 atgtaggtgt aggggtaagg gttcttctcg tctgcgggat actcctcacg ttcagtctct
     2101 tcccaaaggt cccagtttac gacgggaaag aacgaggtag cgtcgggaaa ctcatgatgg
     2161 atgcgggtaa tatacatttt gtcggctatt ctcaaagcct gtctgtagac caacgcgccg
     2221 ccaatgatga atatctcgtc ctctttctca cataaatcca gagcggcccc catagactcg
     2281 caagcgaaac aattcacgaa accagcttcg ggcatagtcg tcaatacgac attcttccga
     2341 ttgggcagtg gcgctacagg gagagactcg aatgtcttac gtcccatgat taccgcatgt
     2401 cccgtggtta attccttgaa acgcttcatg tctgaaggca tgtgacataa taattgctga
     2461 ttctttccga tcgcgctttt atctgcgatt gctgcgatga tagaaattgt actcatagac
     2521 ttattgattt
//
LOCUS       DBMDTB010000208         2493 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_9262_length_2493_cov_13.043060, whole genome shotgun sequence.
ACCESSION   DBMDTB010000208 DBMDTB010000000
VERSION     DBMDTB010000208.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 2493)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 2493)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2493
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_9262_length_2493_cov_13.043060"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..223
                     /locus_tag="ACZPB4_16940"
     CDS             <1..223
                     /locus_tag="ACZPB4_16940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="D-alanyl-D-alanine
                     carboxypeptidase/D-alanyl-D-alanine endopeptidase"
                     /protein_id="HIR1099937.1"
                     /translation="AGVEGSVRNFLKGSSLQGKAHLKSGSMSRVKGYAGYINKGDKQY
                     AIALFVNNYSCDGRPMTVAIEKLLLQLFN"
     gene            complement(231..986)
                     /locus_tag="ACZPB4_16945"
     CDS             complement(231..986)
                     /locus_tag="ACZPB4_16945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005859788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HIR1099938.1"
                     /translation="MRLTCAIIDDEPLAVSLLESYVLKTPFLDLQGTYNSALDALSDL
                     RDRPVDLLFLDIQMPELSGLEFSRILNADTRVIFTTAFDQYAVDSYRVNALDYLLKPI
                     SYPDFLASANKALRWYELLRKPVSSEEKEGSAPIAEKGGMESIFVKSEYKLLQIELRK
                     ILYIEGLKDYVKIFVEDESRPVLSLMSMKSLEDMLPSDRFVRVHRSFIVQPEKIKVIE
                     RNRIVFGKEYIPISDNYKQHFLEMIERRSILPK"
     gene            complement(983..2050)
                     /locus_tag="ACZPB4_16950"
     CDS             complement(983..2050)
                     /locus_tag="ACZPB4_16950"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1099939.1"
                     /translation="MNDTPQSPPIKGLGKLIHIAGWGILFCSPFFFTGRESQVTFEGY
                     FRSIIVPLSFMLVFYLNYGWLVRRYLFNRRTGRFLLINLLLIGGMMLFVHLCMRYFYP
                     PEMHHPPRPPRPLNETVGFFLVNAVIYSLVAGLSVAIKMTDGWYRVAAIQRELEKERA
                     EAELQNLKSQLNPHFLFNTLNNIYSLIAFSPEKAQEAVHDLSRLLRYVLYESSQPFVP
                     LEKDFDFLRNYVELMRIRLPKHVELKTNIVASSPGTLIAPLLFISLVENAFKHGVSNN
                     KPSFIHLDIHQEGAEVVCTIVNSYFPKSPDQDKSGSGIGLVNLEKRLGLLYPGHFSFQ
                     CGREGDNYSSYLSITINETEI"
     gene            complement(2134..>2493)
                     /locus_tag="ACZPB4_16955"
     CDS             complement(2134..>2493)
                     /locus_tag="ACZPB4_16955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010537780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIR1099940.1"
                     /translation="AGISLLVGGIGIMNIMYVSVTERTREIGLRMSIGAKGMDILAQF
                     LIESILISVTGGLIGVLFGVGAALIVNVVAHFPIYIQPWSVLLSFVVCTVTGVFFGWY
                     PAKKAAQLDPIEAIRYE"
BASE COUNT          697 a          684 c          559 g          553 t
ORIGIN      
        1 agcgggggta gaaggctcgg tgaggaactt cttaaaaggc tcatccctcc aaggaaaagc
       61 tcatcttaaa agcggaagca tgagccgggt aaaaggatat gcgggatata taaacaaagg
      121 cgataagcaa tacgccatcg ccctattcgt aaacaactat tcctgcgacg gacgtcctat
      181 gaccgtagcg atagagaaat tattgctcca gttgttcaac taaccggcag ttatttcggc
      241 aggatcgatc tacgctctat catctctagg aaatgctgtt tataattgtc ggagatcggg
      301 atatactcct ttccaaagac aatccgattc cgctcgatca ccttgatctt ctccggctgg
      361 acgataaaag agcgatgaac acgcacaaag cgatccgaag gtaacatatc ctccaaactc
      421 ttcatgctca tcaacgaaag gaccggacgg gactcatcct ccacgaatat cttcacgtaa
      481 tcctttaatc cttcaatata taatatcttg cgcagctcta tttgcaacag cttatactca
      541 ctcttgacga aaatactctc catcccgccc ttctctgcga ttggtgcgga tccttccttc
      601 tcttccgaag acaccggctt acggagcagc tcataccatc gcaacgcctt attcgccgag
      661 gcaaggaagt ccggataact aattggcttc aacaaataat ccagcgcgtt tacccggtaa
      721 ctatccacgg catattgatc gaaagccgtc gtaaaaatga cacgggtatc ggcgttcaag
      781 atacgggaga actccaatcc gctcaactcc ggcatctgga tatccagaaa aagcagatcc
      841 accggccgat cccgtaagtc ggaaagagcg tccaaggcac tattataagt cccttgtaaa
      901 tccagaaacg gagttttcaa gacgtagctt tccagcaagc taaccgctaa aggttcatcg
      961 tcaataatag cgcaagtcaa tctcatatct cagtctcgtt tatagtaatt gatagataag
     1021 aagaatagtt atccccctcc cgaccgcatt ggaacgagaa atgccccgga tagagcagcc
     1081 ccaagcgttt ctccagattc accagcccga taccggaacc acttttatct tgatccgggc
     1141 ttttcgggaa atagctattc acaatagtac aaactacctc cgccccctcc tgatggatat
     1201 ccaaatggat gaaagacggc ttattattgc tcaccccatg cttaaacgca ttctcaacca
     1261 aggagataaa caacaggggg gcgatcaagg ttcccgggga ggaagcgacg atattcgttt
     1321 tcagctccac atgtttgggc aggcgtatac gcatcagctc cacataatta cgaaggaagt
     1381 cgaaatcctt ctccaatggg acaaaaggct ggctactctc atacaagaca tagcgaagca
     1441 agcggctcaa atcgtgcacc gcctcctgtg ccttctccgg gctgaacgct atcaagctat
     1501 agatattatt caacgtatta aacaggaaat gcggattaag ctggctcttc aggttctgca
     1561 attccgcctc ggcacgttcc ttctccagtt cccgctggat agccgccacc cggtaccatc
     1621 cgtccgtcat cttgatcgcc acgctaaggc cggctaccaa ggagtagata acggcgttga
     1681 cgagaaagaa ccccaccgtc tcgttcaacg ggcggggcgg acggggtggg tgatgcatct
     1741 ccggcggata gaaatagcgc atgcagagat gcacgaacag catcataccc ccgataagca
     1801 ataggttgat cagcaggaaa cgccctgtcc ggcggttaaa caaataccgc ctcaccagcc
     1861 acccgtaatt caagtagaag acgagcatga aggaaagcgg cacgatgatg ctccggaaat
     1921 agccctcgaa cgtgacttgc gactccctcc ccgtgaagaa aaagggggag cagaacagga
     1981 taccccatcc cgcgatgtgt atcaactttc ccaaaccttt gataggggga gattgtggtg
     2041 tgtcattcat cttattatcc tctttagtgc tacgcaaata tagtcattcc taccgttata
     2101 tgagccatgt agccttatct agtgagcatt cgtctactca tagcgtatgg cctcgatcgg
     2161 gtcgagctgc gccgccttct tggccgggta ccatccgaag aacacgcccg tcaccgtaca
     2221 taccacgaaa gagagcagta cgctccacgg ctggatatag atcgggaaat gcgccacgac
     2281 attcacgatc aaggcggctc ccacgccgaa aagcacgccg atcaatcctc cggtcacgct
     2341 gataaggata gactcgatca agaactgagc caagatatcc atgcctttcg cgccgatact
     2401 catacggagg ccgatctccc gcgtacgctc cgtcacgctc acgtacatga tattcatgat
     2461 accgatacca ccaacgagaa gagagatacc agc
//
LOCUS       DBMDTB010000209         2476 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_9334_length_2476_cov_12.538105, whole genome shotgun sequence.
ACCESSION   DBMDTB010000209 DBMDTB010000000
VERSION     DBMDTB010000209.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 2476)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 2476)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2476
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_9334_length_2476_cov_12.538105"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..2376)
                     /locus_tag="ACZPB4_16960"
     CDS             complement(<1..2376)
                     /locus_tag="ACZPB4_16960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HIR1099941.1"
                     /translation="MRNLNLFIMKCISIYFVTLLLLMSGCESGRRIILKDLRCENLEN
                     PVAIDNTHPHFSWKIETDGQTMRQAYFEIQVATDSSLLAQGKADLWNSGKVESSASVM
                     VPYRGKELRSSVLAYWKVRVWGDKGESSDWSPINRFGIGLLDKAEWQGKYIGMPDEKN
                     PMLRKKFELQDRDATLLLHVNSLGYHEIYLNGKKVSEDVLSPAVSQLNKRSLSVTYDL
                     TSYAKQGTNDLWVWLGRGWYRKATFNAVHDGPLVKLQLDEIQRNGTTSTLLVTDSSWE
                     GRGSMYGETGTGTWYPHQFGGECVDGRKALPDLTTATLDKLDWKPVLEVEVPGIEVSP
                     QMCEPNRIQEIIRPKGIKQIGDSIWLVDMGKALNGWVELSFPKLPEGHRVRMEYTDWL
                     NENEDFKPQEENGQYEDWYIGSGQGKEVFRNKFNHHAFQYIRISGLAKAPEEVTGYLI
                     HTDYKDASSFECSDPDLNAIYAMIKYTFKNLAFSGYIVDCPHYERMGYGGDGNASCKS
                     FQTLYEGSSVYMNWMQMWQDCIREDGGMPHCVPNPYPAGGGPYWCGFIITGSWQIYLN
                     YGDSRLIERYYPVMRHWLRYVDAYTVDGLLKRWPDTDYRAWYLGDWLAPAGVDYTAQS
                     SVDLVSNCFISDCLTTMEKIAKVLGKAEDAAKYKERRQRLNELIQKTFYDPEKKQYAT
                     GSQIDRIYPMLVGVTDEQHMPEVKEGLYRETLVNCKGHIGSGLVGVTILTDWAIKNGE
                     ADFLYSMLKKREQPGYLYMIDQGASTTWEYWSGERSKVHNCFNGIGAWFCQA"
BASE COUNT          657 a          715 c          448 g          656 t
ORIGIN      
        1 cgcctgacag aaccaagcgc caatgccatt gaaacaatta tgaaccttac tacgttctcc
       61 cgaccagtat tcccaagtcg tagaagcccc ttgatcgatc atatatagat atcccggttg
      121 ctctctcttt ttcagcatgg aatagagaaa atcagcctct ccgttcttta tcgcccaatc
      181 ggtcaagatc gtaacaccca ccaaaccgga accgatatgg cccttacaat tcaccaaagt
      241 ctctcgatat aaaccttcct ttacctcggg catatgctgt tcatctgtca cgccgaccaa
      301 catcggataa atccgatcga tctgggagcc tgtagcgtac tgtttcttct ccggatcata
      361 gaaagtcttc tggataagct cgttcaatcg ttggcgacgc tctttatact tagcggcatc
      421 ctccgctttc cccaatacct tcgcgatctt ctccatcgta gtgaggcaat cgcttataaa
      481 gcagttgcta accagatcta ccgatgactg cgccgtataa tcgacacccg ccggagccaa
      541 ccaatcccct aaataccatg cccgataatc cgtatccggc caacgtttca gcaacccatc
      601 gaccgtatac gcatccacat aacgcaacca atgtcgcata accggataat atcgctcgat
      661 cagacggcta tccccataat tcaaataaat ctgccacgat cccgtgataa taaaaccaca
      721 ccaatacgga ccacctcccg ccgggtatgg attcggtacg caatgcggca tgcccccatc
      781 ctcacggatg caatcctgcc acatctgcat ccagttcata tacacggaag agccctcata
      841 caatgtctgg aaactcttac aagaggcatt tccatcccca ccgtatccca tacgctcata
      901 atgcgggcag tctacgatat aaccactgaa agctaggttc ttgaaagtat atttgatcat
      961 cgcgtagata gcattcaagt ccggatccga gcactcgaaa gacgaggcat ccttataatc
     1021 cgtatgaatc agatagccag ttacctcctc gggagctttc gccaaaccgg atatccttat
     1081 atattgaaac gcatggtggt taaatttatt tcggaatacc tctttgcctt gtccggaacc
     1141 gatataccaa tcctcatact gtccgttctc ctcttgtggc ttgaaatctt cgttttcatt
     1201 taaccaatcc gtatattcca tacggacccg gtggccttcc ggtaattttg ggaaactcag
     1261 ctcaacccaa ccatttaacg cctttcccat atctacgagc caaatactgt cccctatttg
     1321 tttgattcct ttgggacgga tgatctcttg tattcgatta ggctcacaca tctggggact
     1381 tacctctatc ccgggtacct ccacctccaa caccggcttc caatccagtt tgtcgagcgt
     1441 agccgttgtc aaatccggca acgccttccg cccatccaca cattcacccc cgaattgatg
     1501 gggataccaa gtaccggtac cggtctcacc atacatactt ccccggcctt cccaagagct
     1561 atccgtaacg agtagcgtac ttgtagtgcc atttctttga atctcgtcca attgcagttt
     1621 aaccaacggc ccatcatgaa cggcattaaa agtagctttt ctgtaccaac cacggcccaa
     1681 ccagacccat aaatcgtttg tcccctgttt cgcatacgac gtaagatcat acgtcacgga
     1741 caaggatctt ttgtttagtt gagacaccgc aggcgaaaga acatcttctg ataccttctt
     1801 cccatttaaa tagatctcat gataccctaa ggagtttaca tgaaggagta atgtggcatc
     1861 acggtcttga agctcgaact tcttccttaa catcggattc ttctcatccg gcatccctat
     1921 atatttccct tgccattccg ctttatccaa aagcccgatc ccaaagcgat tgattggact
     1981 ccaatccgag gattccccct tatcgcccca tacccgaact ttccaatagg ccagcacact
     2041 agatcgcaac tcttttcctc gataagggac catcacggaa gcggacgatt ccaccttacc
     2101 tgaattccat agatcggctt tgccttgagc cagcaaggaa ctatccgtgg ctacttgtat
     2161 ctcaaaatac gcttgccgca tagtttgccc gtctgtctcg attttccagc taaaatgggg
     2221 atgggtattg tcgattgcga ccggattctc caagttctca caacgaagat cttttaagat
     2281 gatcctccgc ccggattcac agcccgacat cagtaacaat agggtcacaa agtagataga
     2341 tatacatttc atgataaata gattgagatt acgcatgaat atactttcta atggcttacg
     2401 atacttatat ccccggtaaa tattaagatt tattaaacaa gaaaggcgag ccactcgcaa
     2461 atgactcgcc ttccta
//
LOCUS       DBMDTB010000210         2400 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_9701_length_2400_cov_6.958678, whole genome shotgun sequence.
ACCESSION   DBMDTB010000210 DBMDTB010000000
VERSION     DBMDTB010000210.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 2400)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 2400)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2400
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_9701_length_2400_cov_6.958678"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..662)
                     /locus_tag="ACZPB4_16965"
     CDS             complement(<1..662)
                     /locus_tag="ACZPB4_16965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1099942.1"
                     /translation="MRNTYLVLFIYLMIPMFSLAENTYTTQQREDSLLSLLKSSPTVD
                     EQIKLYKDLATMYRQTPKEIVYLNKMADVASSTLKGHASLYYAWANLSRHYYNIQNRD
                     SLIYWSHKIDSLAAAKNEVPDALFDARGFICQMDLWDGNYELAMNGAISLYNYARDTK
                     SEYGLICCNENLGLIYQEIHRDSDAIVAYREGLDLLQKRGDNPKFEMQYMGNLIESYL
                     RT"
     gene            complement(743..>2400)
                     /locus_tag="ACZPB4_16970"
     CDS             complement(743..>2400)
                     /locus_tag="ACZPB4_16970"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIR1099943.1"
                     /translation="QREREFAQEKLNNVLSNYNYQLFRKCQQSTDINQTVISFMDDIP
                     QKDLRVTIIDPSGDVLFDNSGTDEFNNHNDRSEVRKARLYNEGFAIRSSESTGKRYFY
                     SASNIGGYIYRSALPYDPYVRGILTVNKDFIYFMALMTLIFFFVLSRFTFSIGKTISK
                     LRDFALNVEKDRMPAVDYVFPNDELGDISQNIVTLYHRQQKAKNELSMEREKLIKHFQ
                     YSKEGFAMFTSEGREILSNILFIQFINVISDTQIHQVEDVTDIAELEPIRTFLNKNIR
                     NLNRKKKVLRESVTIDKNGKIFLIECILFLDNSYEISINDISRQEEESRMKRQLTQNV
                     SHELKTPVSSIQGYLETILSNPDLSPDKRQFFLERCYSQSTRLTGLLRDISVLNRLDE
                     ASEMFDLTEVNITKLIAEIQKECSQDMEEKHITSEIILPGDPTVFGNNSLLYSIFRNL
                     YDNAIAYAGENIKITVNCYKEDPKYYYFSFSDNGVGIPEEHINRIFERFYRVDKGRSR
                     KIGGTGLGLSIVKNGVNFHKGQISAKSSPGKGVTFFFTLKKKL"
BASE COUNT          641 a          492 c          476 g          791 t
ORIGIN      
        1 tcggttcgaa gataagattc gatgaggttt cccatgtatt gcatctcgaa tttcggattg
       61 tcacctcgtt tctgtaataa atcgagacct tcccgataag ctactatcgc atcactatcc
      121 cgatgtatct cttgatagat taaacctagg ttctcattgc aacaaatcaa tccatattca
      181 ctttttgtat cacgggcata gttgtatagg ctgatcgccc cgttcattgc taactcataa
      241 ttgccgtccc atagatccat ttggcaaatg aatcctcgtg catcgaataa tgcgtctgga
      301 acctcattct tggccgcggc caatgaatct atcttatgcg accagtaaat caggctatcc
      361 ctgttttgta tattgtaata atggcgggat aagttggccc atgcgtaata taaagaagca
      421 tgacctttca aagtggagct tgccacatcc gccattttgt ttaggtaaac aatctccttg
      481 ggcgtttgcc tgtacattgt cgctaaatct ttatataact tgatctgttc atctacggtt
      541 ggcgaggact ttaataggga taaaagacta tcttcccttt gttgggtagt ataggtgttt
      601 tccgctaaag aaaacattgg gatcattaaa tagataaata atactaaata ggtatttctc
      661 atgatattgt atgatgttca atacaaaaat acattttaat attaaatatc aagcgtatgt
      721 tatggaattt tcgaggtctg ccttatagtt tctttttcaa agtgaagaaa aaagtaaccc
      781 cttttcccgg actgctcttc gccgatattt gtcctttatg aaaattaacc ccgtttttaa
      841 cgatagataa tcctaatccg gttcctccga tcttacgact gcgtcccttg tctacccggt
      901 agaagcgctc gaatatgcga ttgatatgtt cttccgggat acccactcca ttatcggaga
      961 agctaaagta ataatattta ggatcttctt tatagcagtt gacggtaatc tttatgtttt
     1021 ctcccgcata agcgatcgcg ttgtcatata gattccggaa tatggaatag agtagggagt
     1081 tattcccgaa cacggtcgga tctcccggga ggataatttc cgacgtgatg tgtttttctt
     1141 ccatatcttg ggagcattct ttttgtatct cggcgataag cttcgtgata tttacttccg
     1201 tgaggtcgaa catctcggat gcctcgtcaa gtctgtttaa tacggaaata tctcgtaata
     1261 atcctgtaag gcgggtactt tgggaataac aacgttccaa gaaaaattga cgtttgtccg
     1321 gactcaaatc tgggttggat aggattgttt ccaaataccc ttgaatgctg ctgaccggtg
     1381 ttttcagctc gtgagagacg ttctgcgtaa gctgtcgttt catccggctt tcttcttctt
     1441 gacgggatat atcattaata gagatctcat aactattatc gaggaataaa atacattcga
     1501 tcaagaatat tttaccgttc ttgtcaatag tcacggactc tcttaatact ttctttttcc
     1561 gattcagatt ccggatattc ttattcaaga aggtacggat tggttctaat tcggctatat
     1621 cagtaacgtc ttccacttgg tggatctggg tgtcggatat gacatttatg aattgaatga
     1681 ataggatgtt agaaagaatc tcccgccctt cactcgtaaa catagcgaat ccttccttgg
     1741 aatattggaa atgtttgata agcttttccc gttccatgga taactcgttt ttcgctttct
     1801 gctgccgatg gtataaggtt acgatattct gtgagatatc acctagttca tcattcggga
     1861 aaacataatc gaccgcaggc attcgatctt tctctacgtt taaggcgaaa tcccttagtt
     1921 tggatatcgt tttacctatg ctgaaagtaa aacgggaaag gacaaagaag aaaatcaagg
     1981 tcatcaatgc catgaaataa atgaagtcct tgtttaccgt caatatccct cttacatatg
     2041 gatcataggg cagggctgag cggtaaatat aacctcctat attcgatgcc gaatagaaat
     2101 acctttttcc cgtagattct gaggaacgga tagcgaaccc ttcattatat aatcgggctt
     2161 tgcgtacctc gcttcgatcg ttatgattat tgaactcatc cgtcccgcta ttatcaaaca
     2221 atacgtcgcc ggacggatct ataatggtta cccgcaaatc cttttgaggg atgtcgtcca
     2281 tgaaacttat tacggtctgg ttgatgtccg tactttgttg gcatttgcgg aataattggt
     2341 aattatagtt actcaacaca ttgttcaact tttcttgcgc gaactccctt tcccgctgat
//
LOCUS       DBMDTB010000211         2397 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_9719_length_2397_cov_9.256098, whole genome shotgun sequence.
ACCESSION   DBMDTB010000211 DBMDTB010000000
VERSION     DBMDTB010000211.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 2397)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 2397)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2397
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_9719_length_2397_cov_9.256098"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..428
                     /locus_tag="ACZPB4_16975"
     CDS             <1..428
                     /locus_tag="ACZPB4_16975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HIR1099944.1"
                     /translation="DLKCSVADLITDKALKKKLKLTDYLTDKVGMPTLLDIMEELDKP
                     GRDPRQTIQVFAFDPTVKTIEDLKEGQVLPGIVTNITNFGCFVDVGIKENGLVHISEL
                     ADRFVSDPTQVVSIHQHVKVKVLSVDLSRKRVQLSMKGI"
     gene            432..914
                     /gene="ybaK"
                     /locus_tag="ACZPB4_16980"
     CDS             432..914
                     /gene="ybaK"
                     /locus_tag="ACZPB4_16980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA deacylase
                     activity [Evidence IEA];
                     GO_process: GO:0043039 - tRNA aminoacylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HIR1099945.1"
                     /translation="MKEKINKTNVARLLDKAKIAYQLVPYEVDENDLSATHVAEQLGE
                     DIAQVFKTLILHGDKSGYFVCVIPGADEVDLKKAAKVSGNKKCEMIPVKELLPLTGYI
                     RGGCSPIGMKKHFPTYIHPTASGFDKIYVSAGQRGLQIQIAPADLIKVAQAIEADLIA
                     "
     gene            complement(1039..1443)
                     /locus_tag="ACZPB4_16985"
     CDS             complement(1039..1443)
                     /locus_tag="ACZPB4_16985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin-like domain-containing protein"
                     /protein_id="HIR1099946.1"
                     /translation="MMKNLIAITCFVVALVSCNKVEHKLEGKWQLKTVEANGVVQTVD
                     TVWYNFQTSLFEYQLYDPAKDVYRTNFGYKTLEGDTKLDLELVNYGGTPLEQFMRYTD
                     WTSPKQTFTIEQSSVTNLVMSCEGRTYTFKKF"
     gene            1603..2184
                     /locus_tag="ACZPB4_16990"
     CDS             1603..2184
                     /locus_tag="ACZPB4_16990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009268 - response to pH [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HdeD family acid-resistance protein"
                     /protein_id="HIR1099947.1"
                     /translation="MKTFIDKMDYAVKNWWLSLLVGLLYIIVAIYLMFAPLASYVALS
                     ILFSVSMFVSGLFEIAFALANKKGISSWGWYLAGGIIDLILGIFLMASPGLSMEVLPF
                     VLAFWLMFRGFSATGYSMDLKRYGTRNWGWYMVFGILAILCSIGVIWQPALGAFTLVY
                     MIAYALLIIGIFRVMLSFELKSLHKRNKEAQAE"
     gene            2280..>2397
                     /locus_tag="ACZPB4_16995"
     CDS             2280..>2397
                     /locus_tag="ACZPB4_16995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIR1099948.1"
                     /translation="MNANLPQLDLPRDYVVGNDITEAILNFYKQTCRLKAGIF"
BASE COUNT          679 a          532 c          527 g          659 t
ORIGIN      
        1 aggacctaaa atgctcggta gccgacctga tcaccgacaa agcgcttaaa aagaaactaa
       61 aactaacgga ctaccttacg gataaggtcg ggatgcctac cttgcttgat atcatggaag
      121 aactggataa accgggccgt gatccccgcc aaacgatcca agtatttgcg ttcgatccta
      181 cggtgaaaac gatcgaggat ttaaaagaag ggcaagtatt gcccggtatc gtaaccaaca
      241 tcaccaactt cggttgtttc gtcgatgtag ggatcaagga aaacgggctt gtccatatct
      301 ccgagctggc ggatcgtttc gtaagcgatc ctacccaagt ggtctccatc catcagcatg
      361 tcaaggtgaa ggttctaagc gtagacctat ccagaaaacg tgttcaatta tccatgaaag
      421 ggatctaaac gatgaaagag aagattaata agacaaacgt ggcgcgcctg ctggacaagg
      481 ctaagatcgc ctaccagctc gtgccttatg aagtagacga gaatgacctg agcgctacgc
      541 atgtagcgga gcagctaggg gaagatatcg cccaagtatt caagaccttg atcttacatg
      601 gcgataagag cggttatttc gtatgcgtga tccccggagc ggacgaggtg gacttgaaaa
      661 aggcggccaa ggtatctggg aacaagaaat gtgagatgat ccccgtgaaa gagttgttac
      721 cgcttaccgg ttatatccgg ggaggatgct cgcctatcgg catgaaaaag catttcccta
      781 catatatcca tcctacggca tccggcttcg ataagatcta tgtaagcgcc ggacaacgag
      841 gcttgcagat acagatagcc cccgccgatt taatcaaggt ggcacaagct atagaagcgg
      901 atttgatcgc atgatctaac atcgctgaga gtacttcgta agaagtactc cagtactccg
      961 caaagagtat cgcagtactt cttagggagt actggagtac tccttatgag ggactgagat
     1021 caaacagcac atgatatctt agaatttctt aaacgtatac gttcttcctt cgcagctcat
     1081 taccagattc gtcacagatg actgctcgat cgtgaaagtt tgtttaggtg aggtccaatc
     1141 cgtataacgc atgaattgtt ccaaaggcgt acctccatag ttgaccaact ccagatccag
     1201 tttcgtatct ccctccaacg tcttataacc gaaattcgta cgatatacgt cctttgccgg
     1261 gtcatataat tggtactcga acaaagaggt ctggaagtta taccaaaccg tatccaccgt
     1321 ctggaccacc ccattcgcct ctacggtttt caattgccat ttcccttcca gcttatgttc
     1381 caccttatta caagacacca acgccacgac aaaacaagtt atcgctatca aatttttcat
     1441 cataatcctc gtacttatat acctatattg atttgaaacg tcaaagaaaa gaattaattt
     1501 ccaaaggaca aagtttttaa ggatatccta gccacaaata cccagaactt tttcttcctc
     1561 ccctttgtta attgggtaat tacaatacaa atattatcca atatgaaaac atttattgat
     1621 aaaatggatt atgcggtcaa gaattggtgg ttatcactat tggtcggact gctttacatc
     1681 atcgtcgcta tttatttaat gttcgcacca ttggcgagct acgtagcgct tagtatctta
     1741 ttcagcgtct ctatgttcgt aagcggcttg ttcgagatcg ctttcgcctt ggcgaacaaa
     1801 aagggtatca gcagttgggg atggtatttg gccggaggta ttatcgactt gatcttaggt
     1861 atattcttga tggcaagccc gggacttagc atggaggtgc ttccgtttgt cttggcattc
     1921 tggcttatgt tcagaggctt ctcggctacc ggttattcga tggacctgaa acgatacggc
     1981 acacggaact ggggttggta catggtcttc ggtatcttgg ctatcctttg ctccatcggt
     2041 gttatctggc aacccgccct aggggctttc acgttggttt acatgatcgc ttatgcctta
     2101 ttaataatag gtatattccg tgtcatgcta tccttcgaac tgaaaagcct gcataaaaga
     2161 aataaggaag cacaagcgga ataagtctga ttcaaggatt aattggtcta tttttaaatt
     2221 atccagtaag tcaacaccac ttttattatt tttgtgttca atcattaata aattaacgga
     2281 tgaacgcaaa cttaccacaa ttagatttgc cccgggatta tgtcgtagga aacgacatta
     2341 ccgaggcaat cttaaacttt tacaagcaga cttgccggtt aaaagcaggt attttcg
//
LOCUS       DBMDTB010000212         2378 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_9827_length_2378_cov_11.152833, whole genome shotgun sequence.
ACCESSION   DBMDTB010000212 DBMDTB010000000
VERSION     DBMDTB010000212.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 2378)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 2378)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2378
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_9827_length_2378_cov_11.152833"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..2194
                     /gene="tamL"
                     /locus_tag="ACZPB4_17000"
     CDS             <1..2194
                     /gene="tamL"
                     /locus_tag="ACZPB4_17000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="translocation and assembly module lipoprotein
                     TamL"
                     /protein_id="HIR1099949.1"
                     /translation="QQPNFKVFGLMKWQLFVYDWSGKNEKKWINKQLRRIGEPPVVLD
                     TMLVEQSAMELERFYINKGYVHADVSTTIDTARHKKAVVTYHIKANDPYRIRNYTMKF
                     PDPKIDSLAHLKAPRRSPLASAFRSSQEEYNQLVKEGTLFDRDILDKERERITTLLRW
                     NGYYGFNRDYLGYIADSSFNQNVVDLDMSMKPYRKVLPNGSVEDQPHRQYYIKDVTVL
                     TDYNPMGVGEDASFMATDTMLSAGVNIVYGRNGKSIRPSVLRRSTYIRPGQLFSEKNI
                     EQTYSAFASLRALRNVNIRFTEVEERDTMKLDCYILTSPAKINTVGVDLEGTNSAGDY
                     GFASSLNYQHRNIFRGSELFSARVRGAYEALSGNKANGFGNYWELGAEGSLLFPRFLF
                     PFLSSDFRRRLRASTEAKISYNLQKRPEYTRAILSGGWSYIWQDRGNTQARHTFKLVD
                     LNYVYLPDKNMDFINSLPDYMVLYNYTNHFIMSSGYTYSFSNYSPQNRLRNTHSLRAS
                     VEVAGNLLSAFSHLTGAKKNDDGYYELFGTEYAQYVKLDFDFSKGIVLDSRNKLAFHI
                     GVGVGMAYGNSNYLPFERAYFSGGANSVRGWSVRELGPGSMEVDSTTSFALQSGDIRL
                     DLNLEYRTKLFWKFELAAYIDAGNIWTRNVSDERYKAGNFDFSRFYKEIAVSYGLGLR
                     LDFDFFLLRLDTGFKAYNPQEKKSRRWAITRPNFKDNFALHFAVGYPF"
     gene            2273..2346
                     /locus_tag="ACZPB4_17005"
     tRNA            2273..2346
                     /locus_tag="ACZPB4_17005"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2307..2309,aa:Arg,seq:tct)
BASE COUNT          625 a          427 c          633 g          693 t
ORIGIN      
        1 gcagcaacca aacttcaagg tgtttggtct gatgaagtgg cagttgtttg tctatgattg
       61 gtctggtaag aatgagaaga aatggatcaa taaacagtta cgtaggattg gtgagcctcc
      121 cgtggtgctg gatacgatgt tggtggaaca gtccgccatg gaactagagc gtttttacat
      181 taataaaggg tatgtccatg cggatgtatc aacgacgatc gatacggcac gccataagaa
      241 agcggttgta acttaccata taaaggcgaa cgatccgtat aggatacgca attacacgat
      301 gaagttcccc gatccgaaaa ttgatagttt ggcacatctg aaagcgcctc gccgctctcc
      361 cttagcttct gcgttccggt cctcacagga agagtataac caattagtta aggaaggaac
      421 tttatttgac cgggatatat tggacaagga gcgggagcgt attacgacct tacttcgctg
      481 gaacgggtat tatggtttta atcgggatta tttaggatat atcgctgata gttcttttaa
      541 ccaaaatgtc gtggatcttg atatgtccat gaaaccttat cggaaggtgt tgcccaatgg
      601 gtcggtagag gatcagccgc atcgtcagta ttatattaag gatgtaacgg tcttaaccga
      661 ttataatccg atgggggtag gagaggacgc tagtttcatg gctacagata cgatgctcag
      721 cgcaggggtg aatatcgtat atggccggaa cgggaagagt atccgtccga gcgtgctccg
      781 gaggagtact tatattcggc cggggcaatt atttagtgag aagaatatag agcagaccta
      841 ttcggcgttc gcttctctaa gggctttgag gaacgtaaat atacgtttta cggaagtaga
      901 ggagcgggat acgatgaagt tggattgtta cattctcact tctcccgcga agataaatac
      961 ggtgggagtg gatttggaag gtactaactc ggcgggtgac tatgggtttg cctccagctt
     1021 gaattatcag cataggaata tcttccgagg atcggagctg ttctcggcga gggtgagagg
     1081 ggcttacgag gcgttatccg gaaataaggc gaatggcttt ggtaattact gggagttagg
     1141 tgcggaaggg tctttgctgt ttcctcgttt tttgttcccg ttcttgagtt cggattttcg
     1201 taggcggcta cgtgcgtcaa ctgaagcgaa aataagttac aacctgcaaa aacgtccgga
     1261 gtatacgagg gcgattctat ctggtggttg gagttatatt tggcaagatc ggggcaatac
     1321 acaggcacgc cataccttta agcttgtaga cttgaattat gtgtatttgc cggataagaa
     1381 tatggacttt atcaatagct tgccggatta tatggtgttg tataactata cgaaccattt
     1441 tatcatgagt tcgggatata cttattcctt cagtaattat tctccccaga atcgtttgag
     1501 aaacacgcat tccctacgtg cgtcggtcga ggtcgcaggg aatttgttga gtgccttttc
     1561 gcatcttacg ggggcaaaga aaaatgatga cggttattat gagttgtttg gtacggaata
     1621 tgcgcaatat gtgaaattgg atttcgattt tagtaaagga atcgtgcttg acagtcgtaa
     1681 caagttagct ttccatatag gagtgggagt ggggatggct tatggtaact caaactattt
     1741 accttttgag cgtgcttatt tctcgggggg agcgaatagt gtccggggat ggtctgtacg
     1801 agagttaggt ccgggtagta tggaagttga cagcacgact tctttcgctc ttcaatcggg
     1861 ggatatccgc ttggatttga acttggaata tcgaacgaaa cttttttgga agtttgaatt
     1921 ggcggcttac atagatgccg gaaacatatg gacccggaat gtatcagatg aacgctataa
     1981 ggctggaaac tttgatttct ctcgttttta taaggagatc gctgtttcct atggtttggg
     2041 acttcgtttg gactttgatt tctttctact acgtttagat acaggcttca aggcttataa
     2101 tcctcaggag aaaaagtcta ggcgttgggc gataacccgt cctaatttca aggataattt
     2161 cgccttgcat tttgccgttg gttatccatt ctaaattcaa tatgtaaaaa agtgtactaa
     2221 aagtttgcaa ggaaaagaaa aatccttacc tttgcaccac gaaaataagg atggtcaggt
     2281 agctcagctg gatagagcaa cagccttcta agctgtgggt cctgggttcg aatcccagcc
     2341 cgatcacgag ggagattcta aaagagtctc cctttttt
//
LOCUS       DBMDTB010000213         2356 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_9939_length_2356_cov_12.104656, whole genome shotgun sequence.
ACCESSION   DBMDTB010000213 DBMDTB010000000
VERSION     DBMDTB010000213.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 2356)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 2356)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2356
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_9939_length_2356_cov_12.104656"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(24..137)
                     /locus_tag="ACZPB4_17010"
                     /pseudo
     CDS             complement(24..137)
                     /locus_tag="ACZPB4_17010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863846.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
     gene            complement(134..988)
                     /locus_tag="ACZPB4_17015"
                     /pseudo
     CDS             complement(134..988)
                     /locus_tag="ACZPB4_17015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275221.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine peptidase family C39 domain-containing
                     protein"
     gene            complement(992..2239)
                     /locus_tag="ACZPB4_17020"
     CDS             complement(992..2239)
                     /locus_tag="ACZPB4_17020"
                     /inference="COORDINATES: protein motif:HMM:TIGR04150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04150 pseudo-rSAM protein"
                     /protein_id="HIR1099950.1"
                     /translation="MNHINTLWFYLYPYIVISEDLDNYLFYNTSTYNGLSFEKKKTIN
                     PIVEQLQDIEKLYSVKIDVKDLEDDFLYNFVKTIQAYGYGDIIEGDLEKPIIMPPILN
                     LQRGVERLKENKSPISENILSYLHGVEVYINGNCTFDCQHCRDRFKQYLCCTKSANVL
                     DPVLLKNFLFSIYYTGAEITLSGGNIFQYKELENLLPILEGIDATHTLVSDWRNIPED
                     LSLLNKITKKSFRLKVLVNEPTDIFPVIVLAQRIKDLQIKQCWVISITSFPEYEKAEA
                     LSESLSELVDDVTIRPFYTGENIAFFEECIFIDQEELDNIELDRQGVFALQALNTNNF
                     GKITILSDGNVYANVNEKSLGHIQDPIKKMLCEELEKGTSWRRTRYDLAPCSQCRYKL
                     ICPSPSNYELAIGKNNLCHINPL"
BASE COUNT          616 a          523 c          489 g          728 t
ORIGIN      
        1 gtgcatgacg gaccctagcg actttaaaat ccttccttca cgatccgttt gatcgggagg
       61 aagaatcgtt cgatcaagcg taattcttcc gttacgatct ctgcggaggc ttgcgtctcg
      121 ggcgagacgg gcaggtcatg aaagcctcga cgcagtcatg gtctccgatg cgctgcatga
      181 tatcgcccac catcttggta tcgaagaaat gcaggggcag gcgcatcagc ttggcgagga
      241 aatcggagat caaggcgata ttgatcctcg tgtttacgtg cagcaatatc cagctccgta
      301 tgaagtccac ggatagcttg gcgataaaga tcaccaattg cgatataagg atcaaggtta
      361 tgaaacctag gttgttgtcc cgtataccgg tatctaccaa gctctgcgtg aggaaaggca
      421 ggatgagttg cagtacgctg gctgtcacca tgcccagcac gagctgtgcc atctcccgtc
      481 tgtagggcga tatatatcgg aaaaagaatc cgaggttacg tttcctgtct ctcccctcgt
      541 cctccatccc gtagaactcc ggccccggtt ccagcaagag cgccgtcccg gtatcctgcc
      601 cgtccacctt ggtactgacc cagcaccgct tgaactcctc cctcgtatag gtgataagtc
      661 ccgccgccgg gtccgctatg tagaacttcc ctttctttat cttgtagcaa accacgaaat
      721 gccattggtt ccagtgcagt atgcaaggta ggggacattc cttctccaac tcgtccatgg
      781 taatcctcac gcctgacgtt cggaacccga tcgcttccgc cgcctcgctg atacccagca
      841 tggagactcc ttcccgtgtg atgaaggctt tctcacgtaa gttttgaatc gagtacgcac
      901 gtccatagaa ccgggcgatc atacgcaggc aggtagggcc gcagtccatg gagtccggtt
      961 ggcgatatgc ggggaagggc ttaatcactt tttacaaagg attaatatga cataaattgt
     1021 ttttcccgat cgctaactca taattggagg gggacgggca aattaatttg tagcgacatt
     1081 gggagcaagg tgctagatcg tagcgtgtgc ggcgccaaga tgttcccttt tccaattctt
     1141 cgcataacat ctttttaata ggatcttgaa tatggcctag ggacttttcg tttacatttg
     1201 cgtatacgtt accatcagac aagatggtta ttttcccgaa attattcgtg ttgagcgctt
     1261 gaagggcgaa tactccttgc ctatcgagtt ctatgttatc cagttcctct tgatcaataa
     1321 agatacattc ctcaaagaag gctatgttct ccccggtata gaatggccga attgtcacgt
     1381 catctaccaa ctcacttaat gattcgctta acgcttccgc tttttcatat tcagggaagg
     1441 aagttatact gattacccag cattgcttga tttggagatc cttgatcctt tgagcgagaa
     1501 cgataactgg gaagatatca gtcggttcgt ttacaaggac ctttagtcgg aagctctttt
     1561 ttgtgatctt gtttagtaaa cttaaatctt ccggtatatt acgccaatct gagactaatg
     1621 tgtgcgtagc atctattcct tcaagaatag gtaatagatt ttctaattcc ttgtattgaa
     1681 atatatttcc acccgagagc gttatctccg ctcctgtgta atagatggag aataagaaat
     1741 ttttcaataa aacaggatcg agtacgtttg ctgattttgt acaacaaagg tattgtttaa
     1801 acctatctct acaatgctga caatcaaaag tacagttacc atttatgtag acttctaccc
     1861 catgtaaata agataaaata ttttcactaa ttggcgattt attttctttt aatcgttcta
     1921 caccccgttg tagatttaat ataggaggca taataattgg tttttctaga tctccttcaa
     1981 tgatatctcc gtatccatat gcttgaatag ttttcacaaa attgtataag aagtcatcct
     2041 ccaaatcttt tacatcgatt tttacactat acaatttctc aatatcttgc aattgctcta
     2101 caataggatt tattgtcttt tttttctcaa atgacaaacc attatatgta cttgtgttat
     2161 aaaacaaata gttgtctaag tcctcgctaa taacgatata aggataaagg tagaaccaaa
     2221 gtgtatttat atgattcata ttcattattt tactaaagtt acttctttca taatacgatt
     2281 atataaatca ggtttatttg caagtgtttc catgtattga tgtagatagt cttcaaattt
     2341 ttttctgtct gccatt
//
LOCUS       DBMDTB010000214         2294 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_10276_length_2294_cov_11.393069, whole genome shotgun
            sequence.
ACCESSION   DBMDTB010000214 DBMDTB010000000
VERSION     DBMDTB010000214.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 2294)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 2294)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2294
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_10276_length_2294_cov_11.393069"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..159
                     /locus_tag="ACZPB4_17025"
     CDS             <1..159
                     /locus_tag="ACZPB4_17025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010185031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine ABC transporter
                     substrate-binding protein"
                     /protein_id="HIR1099951.1"
                     /translation="LGNIHLSDTEISSLMRAIEETSGTETRAVRQWMDGHRDLVDSWI
                     PEKEEYSR"
     gene            548..1144
                     /locus_tag="ACZPB4_17030"
     CDS             548..1144
                     /locus_tag="ACZPB4_17030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3575 domain-containing protein"
                     /protein_id="HIR1099952.1"
                     /translation="MKKSIFFFFLLFSLQAFSQRVAIKNNLVYDALLTPNLSLEFSLG
                     EKWTLDTQVGMNFFFYENDPTADGYKTRKWSHWLVQPEIRYWACERFNGWFLGLHAHG
                     GQMNVGGINIPFILQNKHKEMKAHRYEGYFYGGGISAGYHWILSDRLNFEAALGIGYA
                     HVRYDKFKCTACGQRTGKGGADYLGPTRVSLSIIYILK"
     gene            1318..>2294
                     /locus_tag="ACZPB4_17035"
     CDS             1318..>2294
                     /locus_tag="ACZPB4_17035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099953.1"
                     /translation="MRVKRSANGKSLRFSLHVDAMTRLESQDVLVIYPSLVSASGDDR
                     IDFAPVGIAGRIRYKAITRSKALGENSRTSRFDNELHPFSDIEEQGGSFQESVPFERW
                     MADGHVTVREELLGCVGCGIRENQGTVAVIDLPVFKEEDYAYDFLEPEKVAVKYYKDS
                     FDSKVTFPVASYELRKAFANNGQELARLEGFISRSLEIKGAELKEVLIEGFASPEGKA
                     EYNQSLAEGRTLALSNYISGKYPGLKKAATYRTVGAGEDWEGLKKLVGISPLSNKEKL
                     LSIIDRYPTDTERESAIRNLDNGRTYGILLKEFYPQLRHTTFRFSFDVRA"
BASE COUNT          642 a          482 c          595 g          575 t
ORIGIN      
        1 ttgggaaata tccacctgtc cgataccgag atcagctccc tgatgcgggc catagaggaa
       61 accagcggga ccgagactag agccgtacgc cagtggatgg atgggcatag ggatttggta
      121 gacagctgga ttccggaaaa agaggaatac agccgatgaa catcacgatg gaatggacgc
      181 tcaagctgtt cacgcccttc ttttaatcag cctcgaaagg gaataccgct ctaaatgtac
      241 gttttgatga tatcactaca cgtgcatgga ataaatggaa taaaaagaca cggctacaga
      301 tatgatttga ggatttgtgg tatgatgaaa tcttatacca ttaccacatt tggaatagca
      361 gaaaagatca agaattatat cttatcgttg atattataga gataacttat tcaaaatgac
      421 ttttatagat aacaaattgt ccgttttatg taacaagtgt agtattatac ttttataact
      481 ctgtatcatc aaaaattaac gttatgaacc aagtggttcg gtcgctaaaa ataatatcag
      541 agtcaaaatg aaaaaaagta tttttttctt cttcctgtta ttcagtttgc aagctttttc
      601 acaaagggtc gcgataaaga acaatctcgt atacgatgcg ctgttgactc ccaacctctc
      661 gctggagttc tctctggggg aaaaatggac cttggatacc caagtgggca tgaatttttt
      721 cttctatgag aacgatccca ccgcagatgg atacaagaca aggaaatgga gccattggct
      781 tgtgcaaccc gagatacgat attgggcttg cgagagattc aacggttggt ttctcgggct
      841 gcacgcgcat ggaggccaga tgaatgtcgg tgggataaac atccctttta ttcttcagaa
      901 caagcataaa gagatgaagg cgcaccgtta tgaaggctat ttctacggtg gcggcatcag
      961 tgccggttat cattggattt tatccgacag actcaatttt gaagccgctt tggggatagg
     1021 atacgcgcac gtgagatatg acaagttcaa atgtacggct tgcggacaaa ggacggggaa
     1081 gggaggcgcc gattacctcg gcccgacaag agtctctctc tcaattattt atatacttaa
     1141 ataaaacagg ccttgggcaa aattagtata agatataaaa atatgaagtg aatgagatcg
     1201 atgcattatt acataaagct gtcagcagtc tgtgcctgcc ttggtttgac ggctatattc
     1261 gggcaggccc aggaggtcgt tgagcggaac ctatcaccat tacattagag atatgacgtg
     1321 agggtcaagc ggagcgcaaa cggaaaaagc ctgcgttttt ccctgcatgt ggacgccatg
     1381 acccggttgg agtcacagga cgttcttgtc atctatccat cactggtttc cgccagtggg
     1441 gatgacagga tcgatttcgc gcctgtcggt attgcgggca ggatacgata taaggctatt
     1501 acgcggtcga aggctctcgg tgagaattcc aggacatctc ggttcgacaa tgagctccat
     1561 cctttttcgg acatagagga gcaggggggt tcctttcagg aatccgtccc gttcgaacgc
     1621 tggatggcgg atggccatgt tacggtgaga gaggaactgc tcggttgcgt gggttgtggc
     1681 atacgtgaga atcaaggtac cgtggctgtc attgacctgc ctgttttcaa ggaggaggat
     1741 tatgcgtatg atttcctcga gccggaaaag gtggcggtca agtattataa agactccttt
     1801 gacagcaagg tcacttttcc cgtagcgagc tacgaactga gaaaggcctt cgcgaataac
     1861 gggcaggagc tcgcccggct ggaaggattc atatcaagaa gtctggaaat aaaaggggcc
     1921 gagttaaaag aggtcctcat agagggcttc gcctctcccg agggtaaagc ggaatataac
     1981 cagtcactgg cggaagggcg taccctagcg ctctcgaatt atatctccgg aaaatacccc
     2041 gggcttaaaa aggccgcgac ttaccggacg gtcggtgctg gagaggattg ggagggcctt
     2101 aaaaagctcg taggcatttc tcccctatcc aataaagaga aattgctgtc tatcatagac
     2161 cgatatccaa cggatacgga acgagagtcc gccatacgta acttggacaa cggcaggacc
     2221 tacggcatcc tcctgaaaga gttttatccg caactccgcc atacgacctt tcgtttcagt
     2281 ttcgacgtaa gggc
//
LOCUS       DBMDTB010000215         2281 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_10358_length_2281_cov_13.503211, whole genome shotgun
            sequence.
ACCESSION   DBMDTB010000215 DBMDTB010000000
VERSION     DBMDTB010000215.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 2281)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 2281)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2281
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_10358_length_2281_cov_13.503211"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..426
                     /locus_tag="ACZPB4_17040"
     CDS             <1..426
                     /locus_tag="ACZPB4_17040"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HIR1099954.1"
                     /translation="NQLKGHAAICGKLAAQIYKMEVLAEGIETNKRNFTRFLAIADRW
                     TADEMLRGTDKNKSSLVFALPHTSGSLSKVLSVLSFYDMNLSKIQSLPIIGREWEYLF
                     YIDLTFTDFTRYKQALDAIRPLTKDLKILGEYAEGRQSV"
     gene            401..1579
                     /locus_tag="ACZPB4_17045"
     CDS             401..1579
                     /locus_tag="ACZPB4_17045"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HIR1099955.1"
                     /translation="MQKEDKVCNITPANRVGSVQEYYFSKKLKEVAEMNAAGKNVINL
                     GVGSPDLPPSEQTIETLCEHARKANEHGYQPYVGIPELRKGFADWYKTWYNVDLDPKT
                     EIQPLIGSKEGILHISLAFLNPGDGVLVPNPGYPTYSSVSKLVEARLIPYELKEELGW
                     QPDFEELEKMDLSNVKLMWTNYPNMPTGANASVELYEKLVAFGRKHGIIICNDNPYSF
                     ILNEHPLSILSIPGAKEICIEMNSMSKAHNMPGWRMAMLASNAQFVQWILKVKSNIDS
                     GQFKPMQYAAVEALSAKKEWYDNMNRVYRSRRDLAGQIMRTLGCEYDENQVGMFLWGR
                     IPDSAESGEAIANKVLYEANVFLTPGFIFGSRGERYIRISLCCKNETLEEALKRIENL
                     "
     gene            1614..>2281
                     /locus_tag="ACZPB4_17050"
     CDS             1614..>2281
                     /locus_tag="ACZPB4_17050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HIR1099956.1"
                     /translation="MEMKIEPLALPGVDTQRPIVIAGPCSAETEEQVLETAQGLASRG
                     VKIFRAGIWKPRTKPGGFEGIGAEGLAWLKKVKKETGMLVSTEVATKDHVFEALKAGI
                     DILWIGARTTVNPFAVQEIADALKGVDVPVLIKNPVNPDLELWIGAFERLYGAGIHRL
                     GAIHRGFSSYDKKIYRNLPLWHIPIELRRRMPDLPIFCDPSHIGGKRELVAPLCQQAM
                     DLSF"
BASE COUNT          636 a          534 c          592 g          519 t
ORIGIN      
        1 aaccaactga aaggacatgc ggcgatatgc gggaaactgg ctgcccagat ctacaagatg
       61 gaagtccttg ccgaggggat cgaaactaac aaacggaatt tcacccgctt cctcgctata
      121 gcggaccgct ggacggcgga tgagatgctt cgaggaaccg ataaaaacaa atcctctctc
      181 gtattcgctc ttccccacac ctccggcagc ctttccaaag tcctctccgt tctctctttt
      241 tacgacatga atctctctaa aatacagtcc ttgcctatta tcgggcgtga atgggaatac
      301 ttgttctaca tcgatcttac tttcacggat tttacccgtt acaaacaagc attggacgct
      361 atcagaccgt taacaaaaga cttaaaaata ttaggcgaat atgcagaagg aagacaaagt
      421 gtgtaacatt acacccgcta accgtgtagg tagcgtacag gaatactact tctccaagaa
      481 actgaaggaa gtagccgaga tgaacgccgc aggcaagaac gtcattaacc ttggcgtagg
      541 cagccccgac cttccacctt cggaacagac catcgagacg ttgtgtgaac atgcccgcaa
      601 agcgaacgag cacggttatc agccgtacgt gggcataccg gaactgcgta agggattcgc
      661 cgattggtac aagacatggt ataacgtaga cttggacccg aaaacagaga tccaaccgct
      721 catcggttcc aaagaaggta tcttgcatat ctcgctggca ttcttgaatc cgggggatgg
      781 cgtactggtt ccgaatccgg gatatccgac atatagttcc gtcagcaaac tggtagaggc
      841 ccgtttgatc ccttacgagc tgaaagagga actgggatgg caaccggatt tcgaggaact
      901 ggagaaaatg gatctctcca acgtaaagct gatgtggacc aattacccga atatgcccac
      961 aggggcgaac gctagcgtag agctatacga gaaactggtg gccttcggcc ggaagcacgg
     1021 tattattata tgtaatgata acccctatag cttcatcttg aacgagcatc cgctaagtat
     1081 cttaagcata ccgggagcca aagagatctg tatcgagatg aactccatga gtaaggctca
     1141 taatatgccg ggttggcgta tggcgatgct ggcttccaac gcccaattcg tccaatggat
     1201 actgaaggta aaaagcaata tcgactccgg gcagttcaag ccgatgcaat atgcggcggt
     1261 agaggcccta agcgcaaaga aagagtggta cgacaacatg aaccgtgtct atcgtagccg
     1321 ccgggacctt gccggacaaa tcatgcgtac cttgggatgc gagtacgacg agaaccaagt
     1381 aggtatgttc ctttggggac gtatccccga ctccgccgag agcggcgagg caatcgccaa
     1441 caaggtgcta tacgaggcaa acgtattcct tacgccggga tttatcttcg gtagccgtgg
     1501 cgagcgttat atccgtatct ccctttgctg caagaacgag actttagaag aagccttgaa
     1561 gagaattgag aatttataac tgaaaattga aaattaaaat atagatcaca aagatggaaa
     1621 tgaagattga accgttagca ttaccgggag ttgacacaca acgtcctatc gtaatcgcag
     1681 gcccttgtag cgccgagaca gaagagcaag tgttagaaac agcccaagga ttagcctcca
     1741 gaggcgttaa gatattccgt gcgggtattt ggaagcctcg tacgaaaccg ggtggattcg
     1801 agggcatcgg agccgaggga ttggcttggt tgaagaaagt gaaaaaagag accggtatgc
     1861 tggtatctac cgaggtagcg actaaagatc atgtattcga ggcattgaaa gccggtatcg
     1921 atatcctttg gatcggagca cgtacgacgg taaatccatt cgctgtccaa gagatcgccg
     1981 acgcgttaaa aggggttgat gtacctgtat tgatcaagaa cccggttaac ccggacttgg
     2041 agttatggat cggagcgttc gagcgtttgt acggagcggg cattcatcgt ttgggtgcta
     2101 tccatagagg tttcagctca tacgacaaga agatctaccg taaccttccg ttgtggcata
     2161 ttcctatcga gcttcgccgc cgtatgccgg acctgcctat tttctgtgat cctagtcaca
     2221 ttggtggtaa gcgtgagttg gtagccccac tttgccagca agcgatggac ttgagtttcg
     2281 a
//
LOCUS       DBMDTB010000216         2223 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_10742_length_2223_cov_10.569274, whole genome shotgun
            sequence.
ACCESSION   DBMDTB010000216 DBMDTB010000000
VERSION     DBMDTB010000216.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 2223)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 2223)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2223
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_10742_length_2223_cov_10.569274"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..690)
                     /locus_tag="ACZPB4_17055"
     CDS             complement(<1..690)
                     /locus_tag="ACZPB4_17055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HIR1099957.1"
                     /translation="MKKRQIPHTYVIIFYIILFCAALTWVIPGGQYTENISPDGERTV
                     VYESVESVPQTWEVLSAFYKGFVDKADIIVFILIIGGAFWIVNDSKAFDIGTVSFLRK
                     ARKMENNPILRKIGIDNFLLTAIMLLFSIFGAVFGMSEETIAFCLVLVPMAISMGYDS
                     ITGVCMVFIAAGLGFAGAILNPFTIGIAQGLAGIPLFSGIEYRIVCWCIINVVGFTWI
                     LRYAAKVKKNPQ"
     gene            complement(687..1958)
                     /locus_tag="ACZPB4_17060"
     CDS             complement(687..1958)
                     /locus_tag="ACZPB4_17060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HIR1099958.1"
                     /translation="MDWIIIGGLLIIIVMQILLRPKQLNNNKEDLEKLLNEIQRSFDR
                     IEKNFREDFRLNREESRLVAKDNREELAHSMNEFREAFERGIDSFNRLQKEKFAALDE
                     RQQRLVDNTEKRLEEIRVTVDEKLQKTLNDRIGQSFRLVTEQLESVQKGLGEMQTLAQ
                     DVGGLKRVLSNVKTRGNIGEIQLSMLLEQLLAPEQYEANVHTRKGSDAVVEFAVKLPG
                     RDDAREFVYLPIDAKFPKDVYEQLLDAYDAADSQAIETAGKLLETTIKKMAKDISDKY
                     LAPPATTDFGIMFLPFEGIYAEVVRRSALLEDLQRNYKVVVTGPTTLAAILNSLQMGF
                     RTLAIQKHSGEVWTILGAVKKEFEKVGGMLEKAQKNLQTASGQIEEVLGTRTRAIQRK
                     LKDVDTLSDREARAILPEIGILTEEDEKAES"
     gene            2123..>2223
                     /locus_tag="ACZPB4_17065"
     CDS             2123..>2223
                     /locus_tag="ACZPB4_17065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005865275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HIR1099959.1"
                     /translation="MAKVTLKGNEIHTNGELPKVGTEAPDFKGVKSD"
BASE COUNT          558 a          520 c          482 g          663 t
ORIGIN      
        1 ttgagggttc ttttttacct tggcggcata acgcaatatc catgtgaagc ctaccacatt
       61 gataatacac caacaaacga tacgatactc gatgccggaa aaaagaggaa ttcctgctaa
      121 gccttgcgct ataccgatag tgaaagggtt taaaatcgct ccggcgaaac ctaatcccgc
      181 cgctataaaa accatacata cgccggttat ggaatcgtat cccatagata tcgccatcgg
      241 gaccaagacc agacaaaaag cgatggtctc ctcactcatc ccgaatacgg ccccgaatat
      301 actgaaaagt agcatgatgg cggtcaataa gaaattatct atgcctattt tacgaaggat
      361 ggggttgttc tccattttgc gtgctttccg taggaaactg actgtcccga tatcaaatgc
      421 cttactgtcg ttcacgatcc agaatgcacc accgatgatg aggatgaaga cgatgatatc
      481 cgccttgtcc acaaatcctt tataaaaggc ggagagtacc tcccatgttt gaggtacgct
      541 ttccacggat tcatatacaa cggtccgctc tccatctggg ctgatatttt ccgtgtattg
      601 cccaccgggg ataacccatg tcaatgcggc gcaaaataag atgatgtaaa aaatgattac
      661 gtaagtgtgg ggtatttgtc tctttttcat gattctgctt tttcgtcttc ttcagttaat
      721 attccgatct cgggaaggat agctcgggcc tcacggtcgc taagcgtatc tacgtctttg
      781 agtttacgtt ggatggcacg ggtacgggta cctaaaacct cttctatttg cccgctggcg
      841 gtttgcaagt tcttttgggc tttctcgagc ataccgccta ctttctcgaa ttcttttttc
      901 acggccccta agatcgtcca tacctcccct gagtgctttt ggatcgccaa tgtacggaag
      961 cccatttgta aactgtttag tatggccgct agggtagtgg gacctgttac gactaccttg
     1021 tagtttcgtt gcaagtcctc caataaagcg gaacggcgta cgacctcggc gtaaatgccc
     1081 tcgaacggca ggaacataat gccgaaatcg gtcgtggcgg gaggcgccag atatttgtcc
     1141 gaaatatctt tagccatctt cttgatcgtt gtctccaata attttccggc tgtctcgatc
     1201 gcttgggaat ctgcggcatc gtaagcgtct aggagctgtt cgtatacatc tttcgggaat
     1261 ttagcgtcta tgggaaggta tacgaattct cgggcatcat cccgcccggg gagcttgacc
     1321 gcaaattcaa cgaccgcatc cgaacctttc cgggtatgta cattcgcctc gtattgctct
     1381 ggtgccaata actgctccaa taacatactg agttggatct ccccgatatt tccccgggtc
     1441 ttaacattac taagtacccg ttttaatccg cctacatcct gcgctaaggt ttgcatctcg
     1501 cccagtcctt tttgtacact ttctaattgt tcggtgacta aacggaaaga ttgcccgata
     1561 cggtcgttca atgtcttttg aagtttctcg tctacggtga ctcggatttc ttccagtctt
     1621 ttttccgtgt tatccactaa tctctgctgg cgttcgtcca aggcggcgaa tttctctttc
     1681 tgcaacctgt taaaagaatc gataccacgt tcgaaagctt ccctgaactc gttcatggaa
     1741 tgagccagtt cttctcggtt atctttcgct accaaacggc tttcttcccg gttcaggcgg
     1801 aagtcttccc taaagttttt ctcgatacgg tcgaacgagc gttgtatctc gtttagcaac
     1861 ttttccaggt cttctttgtt attatttagc tgtttaggac gcaaaaggat ttgcatcacg
     1921 atgattataa gaagtccgcc gataataatc caatccatct gtttttgatt ttgacgtcaa
     1981 agataggtaa tctgtatttt gcaacagcag ttaaatagag ttaaataaaa gaacattgtt
     2041 tattttcgtt tgttttatcg acagaaagct gcttatattt gtgcagccaa cttaagtaag
     2101 actattaaat ttacatacaa agatggcaaa agtaacatta aaaggtaacg agattcatac
     2161 gaacggcgag ttgccaaaag ttgggacaga ggctccggac tttaagggtg taaaaagtga
     2221 ttt
//
LOCUS       DBMDTB010000217         2215 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_10800_length_2215_cov_12.502838, whole genome shotgun
            sequence.
ACCESSION   DBMDTB010000217 DBMDTB010000000
VERSION     DBMDTB010000217.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 2215)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 2215)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2215
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_10800_length_2215_cov_12.502838"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..398)
                     /locus_tag="ACZPB4_17070"
     CDS             complement(<1..398)
                     /locus_tag="ACZPB4_17070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HIR1099960.1"
                     /translation="MKYYSTNKQAPVASLEEAVVKGLAGDKGLYMPEYIDSLDEEVIA
                     NMKNQSFHEIACTVAQMFFGEDIEPEVLDGIVKDTLSFETPVVPVKGNIYSLELFHGP
                     TLAFKDVGGRFMARLLGYFIKKEGLKQVNV"
     gene            complement(402..1610)
                     /locus_tag="ACZPB4_17075"
     CDS             complement(402..1610)
                     /locus_tag="ACZPB4_17075"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cofactor-independent phosphoglycerate mutase"
                     /protein_id="HIR1099961.1"
                     /translation="MKHIIILGDGMADEPIEALGGKTPMQYAKTPYMDKLAELGVTGQ
                     MKTVADDFHPGSEVANMAVLGYDLPSVYEGRGVLEAASIGVALQPGEMAMRCNLICVE
                     GDILKNHSSGHISTEEADELIQCLNERLGSDRVKFYTGVSYRHLLVIKGGDKRLDCTP
                     PHDVPLHPFRPLMIKPEVPEARETADLLNELILKSQEILKDHPVNLKRMAAGKDPANS
                     IWPWSPGYRPAMRTMREMYGFGKGSVISAVDLIRGIGVYAGLEVLHVEGATGLYDTNY
                     EGKAHAALEALKTNDFVYLHIEASDEAGHEGDVDLKIKTIEYLDNRAVRIIYEETQKW
                     DEPVAIAILPDHPTPCSIRTHTNTPVPFLIYKPGEQPDSVTTFDEFSVSNGKYGILEK
                     DQFIKEFLND"
     gene            complement(1613..>2215)
                     /locus_tag="ACZPB4_17080"
     CDS             complement(1613..>2215)
                     /locus_tag="ACZPB4_17080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aspartate kinase/homoserine
                     dehydrogenase I"
                     /protein_id="HIR1099962.1"
                     /translation="INTMNDLINSGDHILKLEAVLSGTLNYIFNTISADIPFSEAIHM
                     AKEAGYAEPDPRIDLSGKDVIRKLVILAREAGYPVEQADVKRNLFIPEKYFEGSLEDF
                     WKNIKDTDAGFEEKRQLLEAEGKRFRFVAKMENGACEVGLQAVDSHHPFYELEGSNNI
                     IMISTERYHEYPMIIKGYGAGADVTAAGVFADIISIANIR"
BASE COUNT          469 a          588 c          550 g          608 t
ORIGIN      
        1 aatacgttta cttgcttcaa tccctctttc tttatgaaat aaccgagcag acgagccatg
       61 aagcgccctc ctacatcctt aaaggccaat gtaggcccgt gaaataactc taagctatag
      121 atattaccct ttacgggtac caccggggtc tcgaaggaga gcgtatcttt tacgataccg
      181 tccaatacct ccggctcgat gtcttccccg aagaacatct gagctactgt gcaggcgatc
      241 tcgtggaagg actggttctt catgttggct atcacctcct cgtccaagga atcgatatac
      301 tcgggcatat ataatccctt atcgccggcc agacctttta cgacggcctc ttctaggctg
      361 gctacagggg cttgtttgtt tgtgctgtaa tatttcatgc tctaatcgtt tagaaattct
      421 tttataaatt gatctttttc cagtatgcca tatttgccgt ttgatacgga gaactcatca
      481 aatgtggtaa cggagtcggg ttgctcgccc ggcttgtaaa tcaggaatgg aaccggggta
      541 ttcgtatgcg tacgtatgga gcaaggagtg gggtggtccg gaaggatagc gattgctacc
      601 ggctcgtccc atttttgcgt ttcctcgtag atgatacgta cggcacggtt gtccagatac
      661 tctatcgtct tgatctttag gtctacgtct ccttcatgcc cggcctcgtc gcttgcctcg
      721 atatgcaggt agacgaagtc gtttgtcttg agggcctcaa gggcggcgtg cgcttttccc
      781 tcgtagttcg tgtcgtataa tccggtagct ccctctacgt gaagcacctc gaggccggcg
      841 taaacgccga ttccccggat gagatcgacg gcggagatca cggaaccttt cccgaagccg
      901 tacatctccc gcatcgttcg catggccgga cggtagcccg gagaccaagg ccagatactg
      961 ttcgccggat ctttccccgc tgccatacgt ttgaggttca ccgggtgatc ctttaagatc
     1021 tcttgggact tgaggattaa ttcgtttaat aaatcggcgg tctctcgtgc ttccggaact
     1081 tccggtttta tcattaaagg ccggaaagga tggaggggta cgtcgtgtgg tggcgtgcaa
     1141 tccagacgct tatcgcctcc tttgattacc aataggtggc ggtaggagac acccgtatag
     1201 aacttgacac ggtcggagcc taatcgctcg ttcaggcatt ggatcaactc gtccgcttcc
     1261 tccgtggaga tatggccgga agagtgattc ttcaagatgt cgccttctac gcagattaag
     1321 ttacaacgca tcgccatctc gccgggttgc agggcgacgc ctatactggc ggcttccaat
     1381 acaccccgtc cctcgtatac ggagggcagg tcatagccta ataccgccat gttcgcgacc
     1441 tcgctaccgg gatggaaatc atccgctacg gttttcatct gcccggttac tcccagttcc
     1501 gccaatttat ccatataagg agtcttggcg tattgcatcg gggtcttgcc tcccagagcc
     1561 tctatcggct cgtcggccat tccatcgcct aaaatgataa tgtgcttcat acctatcgaa
     1621 tattagcaat ggatatgatg tcggcgaata cgccagcggc tgtcacgtcg gctccggcac
     1681 catatccctt gatgatcatt ggatattcat gatatctctc ggtggagatc atgataatat
     1741 tgttgctgcc ctccagttca tagaacggat ggtggctgtc tacggcttgt aggcctacct
     1801 cgcaagcgcc gttctccatc ttcgccacga aacggaagcg tttgccttcc gcttccagta
     1861 gctggcgttt ctcctcgaaa ccggcatctg tatccttgat attcttccag aagtcctcaa
     1921 gggaaccctc gaagtacttt tccgggatga acaggttccg ttttacgtcg gcttgctcca
     1981 ctggataacc ggcctcacga gccaagataa ccagcttacg gattacgtct ttgccgctaa
     2041 ggtcgatacg tgggtccggc tcggcgtatc cggcttcctt tgccatatgg atcgcctcgc
     2101 tgaaaggaat atcggcgctg atcgtattaa agatataatt cagcgtaccg gaaagtacgg
     2161 cctccagttt caatatatgg tcgccgctat tgatcaagtc gttcatcgta ttgat
//
LOCUS       DBMDTB010000218         2192 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_10961_length_2192_cov_9.405548, whole genome shotgun sequence.
ACCESSION   DBMDTB010000218 DBMDTB010000000
VERSION     DBMDTB010000218.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 2192)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 2192)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2192
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_10961_length_2192_cov_9.405548"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..>2192)
                     /locus_tag="ACZPB4_17085"
     CDS             complement(<1..>2192)
                     /locus_tag="ACZPB4_17085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SusC/RagA family TonB-linked outer membrane
                     protein"
                     /protein_id="HIR1099963.1"
                     /translation="NMGVCAFCLVPAMVFAENTHEVTVLNAQQQTRKAVGVVTDKTGE
                     AIIGANVIVKGTTNGTITDMDGRFELDVPINATLQVSYIGFNTQEIVFTGQPSIEVQL
                     VDDTQALDEVVVTALGIKREKKALGYSMSELKGESLTQTRDANVANALAGKVAGLQIK
                     QNGTGVGGSSRIVIRGNNSITGNNQPLIVVDGVPIDNFSGGTDDYWGNGNVDKGSGIS
                     DISPDDIESMSVLKGPAAAALYGSRAGNGVVMITTKKGSQNKGWGVSINSNFTAENPM
                     QTPKFQDVYGQGIDGAFDNNKATSWGAVMDGSPKDMAMGSHRYAARDNNLYKDFLRTG
                     TTWTNSVDLSKSSEDITFRAGVTRLDNKGVVPNSGMDRTSINLRSTAKLSKWLSADVK
                     VNYVSQHTNNRVKLAGDPDNIFLNYLSMPRSVGFSDYDAYKDNDWKRADGKPAGYLID
                     TGANANNPYWSAYRNTNKDKKDRFIGFAALDFTFTDWLSLKLRSGMDNYTIQYETIRA
                     TGNPYWENNGSMTANMEKFTEINSDFLLTAKGNWDRFGIVGTVGGNMMYRNSTWYKES
                     SGEFVIPDFHAIANGKTHGGEYTRNRKQINSLYATASLSWDDYLYLDLTARNDWSSTL
                     PKDNDSYFYPSVGVSWIFTQMLNKMGHNTGILSFGKIRASWAQVGNDTDAYMLRDYYN
                     ISYDIKGGIFNASNEDWMANPNLKNETINSWELGLELKAFENRVGVDVA"
BASE COUNT          592 a          581 c          434 g          585 t
ORIGIN      
        1 gctacgtcga caccaaccct attctcaaac gccttcaact caaggcctaa ctcccaagag
       61 ttgatcgtct cattctttaa atttggattt gccatccaat cctcgttgct ggcattaaaa
      121 ataccccctt taatatcata actgatatta taatagtcac gcagcatata agcgtccgta
      181 tcattaccta cctgagccca agacgcacgg atcttaccga aagaaagaat acccgtgtta
      241 tgccccatct tattcaacat ttgggtgaaa atccagctaa cacctaccga tgggtagaaa
      301 taagagtcat tgtctttcgg aagtgttgaa gaccagtcat tacgagcggt taagtccaaa
      361 tacaaatagt cgtcccaaga caatgatgcc gtagcatata gcgagttgat ttgtttacgg
      421 ttgcgagtat actcaccacc atgtgtctta ccgttggcga tcgcatggaa atcgggaatc
      481 acaaactcac cggatgattc cttgtaccat gtagaattac ggtacatcat attaccacct
      541 accgtaccta cgataccgaa tcgatcccag ttgcctttag cagtcaataa gaaatcggag
      601 ttgatctcgg tgaatttctc catattggca gtcatgctac cgttgttctc ccaatacggg
      661 ttacctgtcg cacgaatcgt ctcatactgg atggtgtaat tatccatacc agagcgaagc
      721 ttcaagctca accaatccgt aaacgtgaaa tccaaggccg cgaatccgat aaaacggtct
      781 ttcttatcct tgttcgtatt gcggtaagcg gaccaatacg ggttattggc gttggctcct
      841 gtgtcgatca gataaccagc gggctttccg tccgcacgtt tccaatcatt atctttatag
      901 gcgtcatagt cagagaagcc cacacttcga ggcatactta aatagttaag gaagatatta
      961 tccgggtcgc ccgctaattt cacacggttg ttcgtatgct ggcttacata attgaccttc
     1021 acgtcagccg ataaccattt agacagctta gccgtagaac gcaaattaat agacgtacga
     1081 tccattccgc tattcgggac aaccccctta ttatccaagc gtgtcacacc ggcacggaaa
     1141 gtgatatcct cggagctctt actcaaatcc acgctattcg tccaagtggt accagtgcgc
     1201 aaaaagtcct tgtacagatt attatctcta gccgcatagc gatgagatcc catcgccata
     1261 tccttaggag aaccatccat aacggcaccc caactcgtcg ctttattatt atcgaaagcg
     1321 ccgtcgatac cttgtccgta tacatcttgg aacttcggag tttgcatcgg gttctcagcc
     1381 gtgaaattcg agttgatact tacgccccaa cctttattct ggctaccttt cttagtcgtg
     1441 atcatcacga caccgttacc tgcacggcta ccatacaacg ccgcggctgc cgggcctttc
     1501 aatacggaca tactctcgat atcatccggg gagatatcag agataccgga acctttatcc
     1561 acgttaccgt taccccaata gtcatccgta ccaccgctaa agttatcgat aggtacaccg
     1621 tccacaacga tcaacggctg gttattacca gtaatagagt tattaccacg aatcacgata
     1681 cgagaggaac caccgacacc ggtaccattt tgcttgatct gcaaacctgc taccttacca
     1741 gccaaagcgt tggccacgtt agcatcacgg gtttgcgtca gggactcacc tttcaattca
     1801 gacatagaat atcccaaagc ctttttctca cgcttgatac ccaaagcggt taccacgact
     1861 tcatccaagg cttgcgtatc atcgaccaat tgaacctcga tagaaggttg tccggtaaag
     1921 acgatctctt gcgtattaaa accgatatag gaaacttgta aagtcgcatt gataggaaca
     1981 tccaactcga aacggccatc catatccgtg atggtaccgt tggtagttcc tttgacaatt
     2041 acgttagcac cgataatagc ctcgcccgtt ttgtccgtaa cgacaccgac tgcttttcgt
     2101 gtctgttgtt gagcgtttaa gactgtgact tcatgcgtgt tctctgcgaa aaccatggcc
     2161 ggtaccaaac agaatgcgca tacccccatg tt
//
LOCUS       DBMDTB010000219         2157 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_11204_length_2157_cov_11.941148, whole genome shotgun
            sequence.
ACCESSION   DBMDTB010000219 DBMDTB010000000
VERSION     DBMDTB010000219.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 2157)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 2157)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2157
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_11204_length_2157_cov_11.941148"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..1105)
                     /gene="uxaC"
                     /locus_tag="ACZPB4_17090"
     CDS             complement(<1..1105)
                     /gene="uxaC"
                     /locus_tag="ACZPB4_17090"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008880 - glucuronate isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HIR1099964.1"
                     /translation="MKNFLDQDFLLQTDTARELYHEHAAKMPIIDYHCHLDPRQIAEN
                     HQFEDLTEIWLGGDHYKWRVMRANGIPEEYITGDKPPYEKFLKWAETMPYTMRNPLYH
                     WTHLELSRIFGIHKVLNPASAEEIYATCTDKLRTPEYRAQAIMKRMNVEVVCTTDDPI
                     DSLEFHQKIRSSGCHIRVYPAWRPDKVLAIDNFKALNDYLSKLEAAADKTILTYKHLL
                     EALQKRHDFFAAQGCRLSDHGLDTFYAEPYTEQEIEVIFLKARMGKSLTEQEVRKYRS
                     ALLYELAAMDARSGWVQQFHIGANRNNNKRMFKLLGPDTGFDAIDDQPVAVSMNRFFS
                     HLDQEGLLAKTIVYNLNPRDTELMVANAYNFNDG"
     gene            complement(1102..1776)
                     /locus_tag="ACZPB4_17095"
     CDS             complement(1102..1776)
                     /locus_tag="ACZPB4_17095"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HIR1099965.1"
                     /translation="MARFNKIQTLQAIIQTGMVPVYYNKEVEIAKQVVKACYEGGVRA
                     FEFTNRGDFAHEVFGELVKYAAKECPELVLGVGSIVDPATAALFIQLGANFVVGPLFN
                     PEIAKICNRRLIPYTPGCGSVSEIGFAQETGCDLCKIFPAGNVGGPSFVKNIKAPMPW
                     ILIMATGAVEPTEENLSAWFKAGVTCVGMGSKLFPKEAIAGNDWQSITDLCRDALSII
                     QKYRQV"
     gene            complement(1813..>2157)
                     /locus_tag="ACZPB4_17100"
     CDS             complement(1813..>2157)
                     /locus_tag="ACZPB4_17100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PfkB family carbohydrate kinase"
                     /protein_id="HIR1099966.1"
                     /translation="MAHFPRARKVIITLRGSINANHNTWGGVLYADNRLYESRRYDIT
                     HIVDRVGGGDSFMGGLIYGLLSYPGDDQKALDFAVAASCLKHTIYGDFNQVTVEEVEK
                     LMSGDTSGRVSR"
BASE COUNT          507 a          523 c          538 g          589 t
ORIGIN      
        1 tgccgtcgtt gaaattgtag gcattggcta ccatcaactc ggtgtcgcgg ggattcaggt
       61 tgtaaacgat cgttttcgct aacagccctt cttgatctaa atggctgaaa aagcggttca
      121 tggaaacagc taccggctga tcatcgatag cgtcgaaacc cgtatctggc cctaataact
      181 tgaacatccg tttgttatta ttccgatttg cgccgatatg gaattgctgt acccatccac
      241 tccgggcatc cattgccgcc aattcgtata gcaatgccga acggtatttg cgaacttcct
      301 gctccgtgag cgatttaccc atacgagcct tgaggaaaat cacctcaatc tcctgctcgg
      361 tataaggttc ggcatagaaa gtatccaacc cgtggtccga taaccggcac ccttgggcgg
      421 cgaagaaatc atgccgcttt tgtaatgcct ccaataaatg cttgtaggtg aggatggtct
      481 tatcggcggc ggcctccagc ttggacaaat agtcatttag cgccttgaaa ttatcgatag
      541 cgagtacctt gtccggtcgc catgccggat atacacggat gtggcatccg cttgaacgta
      601 ttttttgatg gaattccaat gagtctatag gatcgtcggt cgtacaaaca acctctacgt
      661 tcatccgttt catgatggct tgcgcacgat attcgggagt acgcagttta tccgtacaag
      721 ttgcgtagat ttcctcggcg gaagccggat tcaagacttt atggattccg aatatacggc
      781 taagttccag atgtgtccaa tgataaagcg ggtttcgcat cgtgtaaggc atcgtctctg
      841 cccatttaag gaatttctcg taagggggct tatctccggt gatatattct tcgggaatac
      901 cgttcgctct catcacccgc catttgtaat ggtctccgcc cagccatatc tccgtaagat
      961 cctcgaattg atgattctcc gctatttgcc ggggatccag atggcaatgg taatcaatga
     1021 tgggcatctt cgccgcatgc tcgtgatata actcacgggc cgtgtcggtt tggagcaaga
     1081 aatcttgatc taaaaagttt ttcatacttg gcgatacttt tgaatgatag ataaggcgtc
     1141 gcggcataaa tctgtaatgg attgccaatc gtttcccgct atcgcttctt tggggaagag
     1201 tttggatccc attcctacgc aggtcacgcc ggccttgaac caagcggata gattctcctc
     1261 tgtcggctcc acggcaccgg tagccatgat taggatccat ggcatggggg cctttatgtt
     1321 cttgacaaat gagggacctc ctacatttcc ggcggggaat atcttgcaaa ggtcgcaacc
     1381 tgtttcttgg gcaaagccga tctcggatac ggaaccgcag ccgggcgtat aagggatgag
     1441 gcgacggtta catatcttcg ctatctccgg gttaaacagc gggccgacta cgaagtttgc
     1501 ccctagctgt atgaataagg cggctgtggc cgggtctacg atagaaccta cgcccaatac
     1561 taattccgga cattccttgg cggcgtattt taccagctcg ccaaatacct cgtgggcgaa
     1621 atctccccgg ttagtaaact cgaaggctct gacgcctccc tcgtaacagg cttttacaac
     1681 ttgttttgcg atctctacct ctttattata atagacgggc accattccgg tttggatgat
     1741 agcctgtaat gtttgtattt tattgaatcg agccatattg ggaattaaaa attgaaaatt
     1801 gagaattgaa aattagcggg agacacggcc ggaggtgtcg ccggacatga gtttttctac
     1861 ttcctctacg gttacttggt tgaagtctcc gtagatcgtg tgtttcaggc aggaagccgc
     1921 taccgcgaag tccaaggctt tctggtcgtc accggggtag gagagcaaac cgtaaataag
     1981 acctcccata aaagaatcgc ctccacctac acgatctacg atatgggtga tgtcataccg
     2041 gcgggattcg tacaaccggt tgtcggcgta tagcactccg ccccatgtgt tatgattggc
     2101 attgatggag cctcttagcg tgatgataac tttccgggca cgtgggaagt gagccat
//
LOCUS       DBMDTB010000220         2094 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_11649_length_2094_cov_9.440542, whole genome shotgun sequence.
ACCESSION   DBMDTB010000220 DBMDTB010000000
VERSION     DBMDTB010000220.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 2094)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 2094)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2094
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_11649_length_2094_cov_9.440542"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..866)
                     /locus_tag="ACZPB4_17105"
     CDS             complement(<1..866)
                     /locus_tag="ACZPB4_17105"
                     /EC_number="4.4.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0080146 - L-cysteine desulfhydrase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-cysteine desulfidase family protein"
                     /protein_id="HIR1099967.1"
                     /translation="MDTIIKTQIIDLIHREVIPAIGCTEPIAVALAAAKAAEVLGRKP
                     EKIEVYLSANILKNAMGVGIPGTGMVGLPIAIALGSIIGKSAYGLEVLKDLTSEGLKE
                     GKEMVCKKCIGIDLKENVDKLYIEIISSAGNDRSRVIICHEHTHIIYVEKNGEVLTDL
                     RTANASGEEVCENKDLRLSFSMVYEFAMEMPLDEIRFILETAELNKKAAQASMKGNYG
                     HTVSKTVSGAFGRKFMGDSAYTHMLIMTSAACDARMDGAMIPVMSNSGSGNQGIAATL
                     PVLSFAEDIQCS"
     gene            complement(911..1282)
                     /locus_tag="ACZPB4_17110"
     CDS             complement(911..1282)
                     /locus_tag="ACZPB4_17110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005856873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009927 - histidine phosphotransfer kinase
                     activity [Evidence IEA];
                     GO_function: GO:0043424 - protein histidine kinase binding
                     [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hpt domain-containing protein"
                     /protein_id="HIR1099968.1"
                     /translation="MNENDAFYNALIDVAAWDKENTLDRFMNSDSLFKKFLYKFITTD
                     GSYVKLRSSLVERDLENAKLYSHTLKGIAANLGLVNLFDVSNNILSLLREGNLEEALR
                     YEDALGKQYDALRDIVVEFCS"
     gene            1468..>2094
                     /locus_tag="ACZPB4_17115"
     CDS             1468..>2094
                     /locus_tag="ACZPB4_17115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA domain-containing protein"
                     /protein_id="HIR1099969.1"
                     /translation="MGISSPLVDLQNQYDLLQKEYEYEKETYRQQSERTGLRKRVAQG
                     LCWYPVTPGRSYHNSLNQLVIEIERTENREIEHNFEYGRPVCFFTADISGKFKYLDFS
                     ATISYVQEDRMVVVLPTPSALMDIQGKSNDLGVQLYFDETSYKTMFSALSDVMRAKNN
                     QLSHLRDVLLGQEKPRQRELFPIRFPWLNRSQEEAVNKVLGAKQVSIVH"
BASE COUNT          594 a          505 c          408 g          587 t
ORIGIN      
        1 tccgagcatt ggatatcctc ggcgaaagaa agaaccggaa gcgtagcggc gattccttga
       61 ttaccgcttc ccgaattact catcaccggg atcatagcgc catccatgcg agcgtcgcaa
      121 gcggcggaag tcatgatcaa catatgcgta taagcggaat ctcccatgaa cttacggccg
      181 aaagcacccg agaccgtctt gcttacggta tgtccataat tgcctttcat ggaagcttgg
      241 gcggctttct tattcaactc agctgtttct aaaataaaac gaatctcatc caatggcatt
      301 tccatggcaa actcatagac catagagaag gaaagacgta aatccttatt ctcacatact
      361 tcctcgccag aagcgtttgc cgtacgtaaa tcagtcaata cctccccgtt tttctctaca
      421 tatattatat gggtatgctc atggcaaatg atcacccttg aacgatcgtt ccctgctgaa
      481 cttataattt cgatataaag tttatctaca ttctctttca ggtctatacc gatacatttc
      541 ttgcagacca tttccttacc ttctttcaat ccctccgaag tcaagtcttt cagcacctct
      601 agcccataag cggacttacc gatgatcgat cccaaggcga tagcgatagg caaccccacc
      661 atgccagtcc ccgggattcc tactcccatg gcattcttca ggatattggc gctcagataa
      721 acctctatct tctctggctt acgccccagc acttccgccg cttttgcggc cgccaaagcc
      781 acggcaatag gttccgtaca tccgatagca gggattacct ccctgtgaat caaatctata
      841 atttgagttt ttatgatagt atccatactg atagtcttta tttagaatta gatagttaat
      901 atacaataga ttaagaacaa aactcaacaa cgatatctcg caaggcatcg tattgttttc
      961 ccaatgcatc ttcataacgc aacgcttctt ccagattccc ttctctcaac agcgatagta
     1021 tattattcga tacatcgaat agatttacca gacctaaatt agcggctatc cctttcaagg
     1081 tatgcgaata tagcttggca ttctccaaat cccgctctac taaagagctc cgtaatttca
     1141 catacgaacc atctgtagta ataaatttat atagaaactt tttgaagagg ctatcactat
     1201 tcataaaacg atctaaggta ttctctttat cccaagcagc tacatctatt aatgcgttat
     1261 aaaaagcatc gttctcattc atttttttat gatattagtt ttcgtacaaa attaggaatt
     1321 ttatagacac taccaacgtt agcggtattc tttttcttta cttaccgcaa cttgggtacg
     1381 gaacgataat tttagtactt ttgtcgccta cttcgggacc tagaacgccc gggctgtatt
     1441 tatccgatta attgaattga taaaggaatg ggaatttcat cgccgcttgt tgatttgcaa
     1501 aatcaatatg atctcctgca gaaagaatat gaatatgaga aggaaacata ccgacagcaa
     1561 tccgagcgta cgggtttgcg aaaacgagtg gcgcagggcc tctgttggta tccggtcact
     1621 ccgggacgca gttatcataa ctccttaaac caattggtga tcgagatcga aagaacagaa
     1681 aaccgggaga tcgagcataa ttttgagtac gggcgcccgg tttgcttctt tacggcagat
     1741 atcagtggta aatttaagta tctggatttc tccgccacga tcagctacgt gcaagaggac
     1801 cggatggtgg tagttctccc cactccttcc gccttgatgg atatacaagg aaaaagcaat
     1861 gatctcggcg tgcaactcta cttcgacgag accagctata aaacgatgtt ttccgctctc
     1921 tcggacgtga tgcgggcaaa aaacaaccaa ctctctcatc taagggatgt attgctggga
     1981 caggaaaaac cgagacagcg ggaattattc ccgatccgct tcccttggtt gaaccgctcg
     2041 caggaagaag ccgtaaataa ggtattggga gcgaaacaag tatctatcgt acac
//
LOCUS       DBMDTB010000221         2082 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_11746_length_2082_cov_13.252903, whole genome shotgun
            sequence.
ACCESSION   DBMDTB010000221 DBMDTB010000000
VERSION     DBMDTB010000221.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 2082)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 2082)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2082
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_11746_length_2082_cov_13.252903"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            74..>2082
                     /locus_tag="ACZPB4_17120"
     CDS             74..>2082
                     /locus_tag="ACZPB4_17120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-L-arabinofuranosidase domain-containing
                     protein"
                     /protein_id="HIR1099970.1"
                     /translation="MKYLLTITLSSLISITSFSATLPGNEGSININYPNNRYPLASKP
                     YIELPIGDVKPAGWLKIQMERMCTGMTGHLDSIYTKVMGPRNGWLGGDGDVWERGPYW
                     IDGLLPLAYIMNDEALIQKVKPWVEWTLASQKPNGYFGPDTDRDYEPGLQRDNAQDWW
                     PKMVMLKVLQQYYSATNDQRVISFLTNYFKYQLSELPKSPLGKWTFWAEQRGGDNLMV
                     VYWLYNITGDPFLLELGELIHKQTFNWTDVFLNQDHLARQNSLHCVNLAQGFKEPVIY
                     YQQSHNPQNLEAVKEAVRKMRHTIGFPTGLWAGDELLRFGNPTQGSELCTAVEMMFSL
                     EKMLEITGDVQWADHLEKVAYNVLPTQIKDDFSARQYYQQVNQIAITCEGRNFVSPHE
                     DTDIVFGELSGYPCCTSNLHQGWPKFTRHLWFATADNGIASLIYAPSEVTAQVGNDIT
                     VKIAEKTDYPFEEKIDFNLSFPSKKDKKAFFPFHLRIPAWCNNPVITINGEAVSIAAH
                     SGEIVRINREWKDGDHIQLELPMRISTSNWYDDAVVIERGPLLYSLKMDEKWERKVDQ
                     RPESSHKGEWYYEVTSTSPWNYSLIRKYLKEEELEKNFVVRKAENIAPYPWNLENAPI
                     TIKTKGRILPSWKMFKGSAGPVNFFMQANEPMGDEETIELIPYGCT"
BASE COUNT          638 a          454 c          461 g          529 t
ORIGIN      
        1 gcgtgggata accgtaaagc aggaaaaatg agggtatgga tcccctataa cgaataacta
       61 aaaaagcatc aaaatgaagt atttattaac gataacatta tcaagcctaa tctcaattac
      121 ctccttttct gccactttgc cgggaaatga aggttctatc aacattaatt acccgaacaa
      181 tcgttatcca ttagcctcta agccttatat agagttgcct attggggatg ttaaacctgc
      241 gggttggcta aaaatccaaa tggaacgaat gtgtacggga atgaccggcc atctggattc
      301 tatctatacg aaagtaatgg gaccgcgtaa tggttggtta ggcggagatg gagacgtatg
      361 ggagcgaggc ccatactgga tagatggctt actacctttg gcttacatca tgaatgatga
      421 ggccctgatc caaaaagtaa agccttgggt tgaatggaca ttggcctctc aaaagcctaa
      481 cggatatttc gggccagata cagacagaga ctatgaaccc ggcttacaac gggataacgc
      541 acaagattgg tggcccaaaa tggttatgct caaagttctg caacaatatt attccgctac
      601 caacgatcaa agagttatct cgttcctcac taattatttc aaataccagc tttctgaact
      661 acctaaaagt cctctgggaa aatggacttt ctgggctgaa caacgaggag gggataatct
      721 gatggtcgta tattggcttt ataatatcac gggcgatcct ttccttctgg agttaggaga
      781 gttaatccat aagcaaacct tcaattggac cgacgtgttc ttgaaccaag atcatttagc
      841 ccggcaaaac agcctgcatt gtgtaaatct cgcccaagga ttcaaggaac ctgtcattta
      901 ttaccaacag agccataatc ctcaaaatct ggaagcggtt aaggaagctg tacggaaaat
      961 gcgtcatacg attggttttc ctacaggatt atgggcggga gatgaacttt tacgtttcgg
     1021 taacccgaca caaggatcag aactctgtac cgctgtcgag atgatgttct ctctcgagaa
     1081 aatgttagag ataaccggag atgtccagtg ggctgatcat ttagagaaag tcgcatacaa
     1141 tgtactgcca acgcagatca aggatgactt ttccgcacga caatattatc agcaagtcaa
     1201 tcaaatagcg atcacttgcg aaggacgtaa ctttgtctca ccacacgagg acacagacat
     1261 tgttttcgga gaattgagcg gttatccttg ttgtacctcc aatctacatc aaggctggcc
     1321 taaattcaca cgacatctat ggtttgccac cgccgataat ggcatcgctt cacttatcta
     1381 cgcaccatcg gaagtgactg cccaagtggg aaacgacatc acggttaaaa tcgcagagaa
     1441 gaccgattat ccctttgaag aaaagatcga tttcaattta tcgttcccta gcaagaaaga
     1501 caagaaagcc tttttccctt ttcacttgcg tattcctgct tggtgtaata atcccgtgat
     1561 tacgataaat ggcgaggctg tctctatcgc agctcactct ggcgaaatcg tacgaatcaa
     1621 ccgagaatgg aaagatggcg atcatatcca gctagagcta cccatgcgta tatccacaag
     1681 caattggtat gacgatgcgg ttgttatcga acgaggccca ttattgtatt ccctaaagat
     1741 ggatgagaaa tgggaacgca aggttgatca acgcccggag tcttcacata aaggagaatg
     1801 gtattatgag gtcacctcta cttcaccatg gaattattcc ctgattcgca aatatctgaa
     1861 agaagaagaa ctagagaaaa atttcgtcgt tagaaaggca gagaacatcg ccccttaccc
     1921 atggaaccta gagaatgccc ctatcacgat caaaacaaag ggacggatct taccttcatg
     1981 gaaaatgttc aaaggttccg ccggccccgt aaatttcttc atgcaagcca acgaaccgat
     2041 gggtgatgaa gagacgatcg agttaattcc ttatggctgt ac
//
LOCUS       DBMDTB010000222         2042 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_12020_length_2042_cov_8.917568, whole genome shotgun sequence.
ACCESSION   DBMDTB010000222 DBMDTB010000000
VERSION     DBMDTB010000222.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 2042)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 2042)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2042
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_12020_length_2042_cov_8.917568"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..138)
                     /locus_tag="ACZPB4_17125"
     CDS             complement(<1..138)
                     /locus_tag="ACZPB4_17125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HIR1099971.1"
                     /translation="MKSIVLLRHGESVWNKENRFTGWTDVDLTEKGVAEAYRAGNLLK
                     EK"
     gene            complement(153..521)
                     /locus_tag="ACZPB4_17130"
     CDS             complement(153..521)
                     /locus_tag="ACZPB4_17130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005857809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HIR1099972.1"
                     /translation="MVKILLKRIYEEPSEADGYRILLDRLWPRGLKKEDAKFDEWRKD
                     ITPSKELRQWFHEDKDRHWEVFQGRYGMEIKQNPDFIPFLREIEKHPVVTFLTAAKDV
                     QHSHLPILKEAIEDFEKNKS"
     gene            682..1701
                     /locus_tag="ACZPB4_17135"
     CDS             682..1701
                     /locus_tag="ACZPB4_17135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009017225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FecR domain-containing protein"
                     /protein_id="HIR1099973.1"
                     /translation="MEINEDILIRYIDGMLTEEEAAEVKNWRAASLENEKLLEQVYFT
                     TQVASRLKVMRTVNPDEALSRFKSRIHKKEKRLALRQVLGVIQRAAAVLFIPVFLLSA
                     YLFIQQGQGNVRTLAVRTNPGVVSAFDLPDGSKVWLNANSELRYPSDFNADTRTVELT
                     GQGYFEVTKNAHKPFIVKADKDYSVEVLGTSFNVSAYKDESMIETTLVEGSVKLNVVS
                     GGKRMTQTLKPNEKAEYQKGAGKIKVFGVNTEYDTAWKNGEIIFRNHPMDKVLKTLER
                     HYHVVFEVKDNEILKSIITARFKDEQLPQVLEYLKLASGIQYAIHKPTVKDSGSGTSV
                     VEISK"
BASE COUNT          606 a          404 c          464 g          568 t
ORIGIN      
        1 tttttctttc aataggttgc cggccctata agcttcggcc acgccttttt ctgtcaaatc
       61 cacatcggtc caaccggtga accggttctc tttattccat acactttcgc cgtggcgaag
      121 caatacgata cttttcatag gtctttttat ttttatgatt tgtttttctc gaaatcctcg
      181 atggcttctt ttaatatagg tagatgacta tgttgtacat ccttcgctgc cgtgaggaaa
      241 gtgacaaccg gatgcttctc gatctctcgt aagaaaggaa tgaaatccgg gttctgcttg
      301 atctccatcc cgtagcgacc ttggaatact tcccaatgcc tgtctttatc ctcgtggaac
      361 cattggcgta actccttaga tggagtgatg tcttttctcc attcgtcaaa cttcgcatcc
      421 tctttcttaa gtcctctggg ccatagcctg tcgagaagaa tgcgataacc atccgcctca
      481 cttggctcct cataaatccg ttttaaaaga atctttacca taagaagtct cattttgtgg
      541 taaaacagta gaaagaggga tattgttgag cctttcttta ggaacggtat ttttgccatt
      601 attcaatttt cttgaaaaaa atcgtttttt tgtttagtac atcttttgtc tcaactgtat
      661 taattataga aacaagaaaa aatggaaata aacgaagaca tattgatccg atacatcgat
      721 gggatgttga ccgaggagga agctgcggag gtgaaaaact ggcgggccgc ctctctagaa
      781 aacgagaaac tgttggagca ggtctatttt acgactcaag tggcaagtcg cctaaaagtc
      841 atgcggaccg tgaacccgga cgaggcgttg tctcgtttta aatcaagaat ccataagaaa
      901 gagaaaagat tagctttaag acaagtgtta ggtgttattc aacgggctgc ggccgtgtta
      961 ttcattccag tctttctttt atccgcttat ttgttcatac agcagggtca agggaacgtg
     1021 cgtacgctag ccgtacgcac gaatcctggg gtggtttcgg cgttcgattt acctgacggt
     1081 tctaaggttt ggctgaatgc caatagcgaa ttgagatatc cttcggactt caatgcggat
     1141 acccgtacgg tggaattaac cggacaagga tatttcgagg tgacgaagaa tgcccataag
     1201 ccttttattg tgaaagcgga taaagattac tcggtagagg tgttgggaac ttctttcaat
     1261 gtatccgctt acaaagacga gagtatgata gagaccacct tggtagaggg atcggtaaag
     1321 ctgaacgtcg tgtccggagg aaagcgaatg acacagacgt tgaagccaaa cgagaaagcc
     1381 gagtatcaaa agggcgctgg caagatcaag gtgttcggcg tgaataccga atatgacacg
     1441 gcttggaaga acggggagat tatcttcagg aaccatccga tggataaagt attgaaaacg
     1501 ctggaacgtc attatcatgt agtattcgag gtaaaagata acgagatact caagtccata
     1561 ataacagccc gtttcaagga cgagcaattg cctcaagtat tggaatacct gaaattggcg
     1621 tcgggaatcc agtatgcgat acataaacct accgttaagg acagtggatc gggaacctca
     1681 gtcgtggaaa tatcaaaatg agaaataatg tgtaaccttc taaaatacgt ctgcccatga
     1741 agaaagaata aacaaggatt aaaaacatac ggaagaatat tggcgtattc tcccgtacga
     1801 aaagtcaaga agagctgttg gcgcagctac aaataacttt attataaata gtaacactac
     1861 aaaaatatga ataaaattgt aaccttaaat gctttaaggg ggaatagtta ttctcttttt
     1921 cgaaaaattc cgttaatgat taacatgggg gtatgcgcat tctgtttggt accggccatg
     1981 gttttcgcag agaacacgca tgaagtcaca gtcttaaacg ctcaacaaca gacacgaaaa
     2041 gc
//
LOCUS       DBMDTB010000223         2029 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_12114_length_2029_cov_18.566390, whole genome shotgun
            sequence.
ACCESSION   DBMDTB010000223 DBMDTB010000000
VERSION     DBMDTB010000223.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 2029)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 2029)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2029
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_12114_length_2029_cov_18.566390"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..612)
                     /gene="nusG"
                     /locus_tag="ACZPB4_17140"
     CDS             complement(<1..612)
                     /gene="nusG"
                     /locus_tag="ACZPB4_17140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005867671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA];
                     GO_process: GO:0006354 - DNA-templated transcription
                     elongation [Evidence IEA];
                     GO_process: GO:0031564 - transcription antitermination
                     [Evidence IEA];
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HIR1099974.1"
                     /translation="MDILTSKCSDRFMAHVLKRRDQEAVRWYVLTLPTAGGGRDKINP
                     SKGLDAELSRRERRGETLFEYFAPSYVEARKVGGKMVNTKRPLLYNYVFIHASENEIF
                     SLKRTLPLYNFLPRVSSGGQSYFPYLSDREMDTLRWVAASYSNELPVYVPDSGRLLKG
                     DRVRITSGPFADMEAEVVVQPGGGHKDVMVRILDCMWVPLFEVR"
     gene            complement(1059..1991)
                     /locus_tag="ACZPB4_17145"
     CDS             complement(1059..1991)
                     /locus_tag="ACZPB4_17145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009276318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009009 - site-specific recombinase
                     activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HIR1099975.1"
                     /translation="MDEKDLVEGMREYISLLQKEGRYSSAKSYQDAMNSFIRYSGTDR
                     IPYTYINKDTLRRYEAYLLEKGCMRNTVSTYIRRLRCIYNKAVENGEAAFIPSLFKGV
                     FTGVESQRKKSLPLGDLNRLMTVPVKGEKLRKTQLALCLMFQYGGMSFVDFAHLNRGN
                     IKNGILDYNRQKTGTSMRLEVLDTAEAMYKELAGERGGGSGYLFPFLSGTKNGHEEYL
                     EYNAALSRFNRNLKTLKEVAGIVSDVTSYTIRHSFAMALKEQNVPIEMISELLGHKSI
                     KTTQIYLRSFSLEKMTVVNKSCFENVYNYMPEVG"
BASE COUNT          541 a          557 c          424 g          507 t
ORIGIN      
        1 cctcacctcg aacaagggaa cccacatgca atcgaggata cgcaccatca cgtccttatg
       61 gccaccgccc ggctgtacca ccacctcggc ctccatgtcg gcaaacgggc cggaggtgat
      121 acgcacacgg tcgcctttca acaagcggcc gctatctggc acgtatacgg gaagctcgtt
      181 ggagtaagac gccgcgaccc aacgcaaggt atccatctca cgatccgaga ggtagggaaa
      241 gtaagactgt ccacccgagg aaacccgggg taggaaattg tacaggggaa gcgtacgctt
      301 cagactaaag atctcgttct ccgaggcgtg gatgaacacg tagttgtaca gcaggggccg
      361 tttcgtgttg accatcttgc cgcccacttt cctcgcctcg acatatgaag gggcgaaata
      421 ctcgaacagc gtctccccac gacgctcacg gcgggaaagc tcagcgtcca gtcccttcga
      481 ggggttgatc ttgtcacgcc cgccaccggc ggtagggagc gtgagcacgt accagcggac
      541 agcctcttga tcacgtcgct tcagaacatg cgccatgaac ctatccgagc acttgcttgt
      601 caatatatcc atctctatga ttatcttttc tagtggttat cccatggccc gaaaacagac
      661 cccacggcaa ttcagagccc taccaagaat catttatatc atcttgataa acagtgcttt
      721 atatttccaa atatggcatt actgaaaatt accatctctc gaaatcttag gctacttggg
      781 gagtagccta aaaggtgcga gaacggttat cacccggttg tagagacggg gcacgccccg
      841 tctctacagg aatgtatgtt cgatttttta gaagggacgt gatgatgtag gaaatacgag
      901 atcatttcgt ctctattgcc atgtctatac actaggaata agaacgaaga tttaaggaga
      961 atcaaggccg gagcacaaac taaaactaat gattgcttgt tatttgctat tttttgctac
     1021 atttgcaccg tgaaatgaac gctactcccc aagtagcctc atcccacctc tggcatataa
     1081 ttatatacat tctcaaagca agacttgttt accaccgtca ttttctccaa cgagaaactt
     1141 ctcagataaa tctgggttgt cttgatggat ttatggccta ataactcgct gatcatctct
     1201 atggggacat tttgttcctt caatgccatg gcaaaagaat gacggatcgt gtaggaagtc
     1261 acatccgaga ctattccggc aacctctttc aacgtcttca agttccggtt aaaccgggac
     1321 aaggccgcat tgtactcgag atattcctca tggccgttct tcgtcccact taaaaaggga
     1381 aataaatagc cggagcctcc acccctctca cctgccagct ccttatacat agcttccgcc
     1441 gtatccaaga cctccaaccg catagaggtc ccggtcttct ggcgattgta atccaatatg
     1501 ccgttcttga tattacccct attcaaatgg gcgaaatcaa cgaacgacat ccccccatat
     1561 tgaaacatca agcaaagggc cagttgtgtc ttcctcaact tctctccttt taccgggaca
     1621 gtcatcaggc gattcaaatc acccagaggc aaggatttct tgcgctggct ttccacaccc
     1681 gtaaaaaccc ccttgaataa tgaagggata aacgccgcct cgccattctc caccgccttg
     1741 ttatagatac aacgcaaacg gcggatatac gtggagaccg tattacgcat gcagcctttc
     1801 tccaacaaat aagcctcgta ccggcgaaga gtatccttat ttatatatgt atatgggata
     1861 cgatccgtcc cgctataccg tataaaagag ttcatcgcat cctgataact tttcgccgag
     1921 gaataccgtc cttccttttg taacagactt atatactctc gcatcccttc caccaaatct
     1981 ttctcatcca tatctctcta ttttaaattc caactgaaaa caaacacgc
//
LOCUS       DBMDTB010000224         1960 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_12641_length_1960_cov_8.038193, whole genome shotgun sequence.
ACCESSION   DBMDTB010000224 DBMDTB010000000
VERSION     DBMDTB010000224.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 1960)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 1960)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1960
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_12641_length_1960_cov_8.038193"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..1061)
                     /locus_tag="ACZPB4_17150"
     CDS             complement(<1..1061)
                     /locus_tag="ACZPB4_17150"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007758737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HIR1099976.1"
                     /translation="MGGFFGTISNGDCITDLFYGTDYNSHLGTRRGGMATYDKEEGFT
                     RSIHNLENSYFRTKFEPGLPKFKGNAGVGIISDTDAQPIVINSHLGKFAIVTVAKINN
                     LDELEDELLKANMHFSELSSGKTNQTELVALLITQGKDFVEGIENVYNKIKGSCSMLL
                     LTEDGIIAARDKWGRTPIVIGRKDGAYAATSESSSLPNLDYEIEKFIGPGEIVRLRAD
                     GMEQMRKPNEGMQICSFLWVYYGFPVSCYEGKNVEDVRFMSGYKMGQKDDSEVDCACG
                     IPDSGVGMALGYAEGKGVPYHRAIAKYTPTWPRSFTPANQEMRSLVAKMKLIPNRAML
                     EGRRILFCDDSIVRGTQLR"
     gene            complement(1218..1484)
                     /gene="rpmA"
                     /locus_tag="ACZPB4_17155"
     CDS             complement(1218..1484)
                     /gene="rpmA"
                     /locus_tag="ACZPB4_17155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HIR1099977.1"
                     /translation="MAHKKGVGSSKNGRESQSKRLGVKLFGGEVAKAGNIIVRQRGTV
                     HHPGENVGIGKDHTLYALVDGVVTFRRGKENRSFVSVKEVVAEA"
     gene            complement(1507..1824)
                     /gene="rplU"
                     /locus_tag="ACZPB4_17160"
     CDS             complement(1507..1824)
                     /gene="rplU"
                     /locus_tag="ACZPB4_17160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HIR1099978.1"
                     /translation="MYVIVEINGQQFKAEQGKKLFVHHIQNAESGAVVEFDKVLLVDN
                     NGEVTVGVPTVEGAKVVCEVLSPLVKGDKVLVFHKKRRKGYRKLNGHRQQFTEVSIKE
                     VIA"
BASE COUNT          515 a          546 c          333 g          566 t
ORIGIN      
        1 tcacgaagct gtgtaccacg cacgatcgag tcgtcgcaga aaaggatgcg tctgccttcc
       61 agcatcgcac ggttcggtat caatttcatc ttagccacca aggaacgcat ctcttggtta
      121 gccggggtaa aactacgagg ccacgtcggt gtatacttag cgatagcccg atgataaggc
      181 acccccttac cttccgcata ccccaaagcc atacccacac cggagtccgg tataccacaa
      241 gcgcaatcca cctccgagtc atccttctgc cccatcttat agccactcat aaaccggaca
      301 tcctccacgt tctttccctc atagcaagaa acagggaatc cataatatac ccaaaggaaa
      361 gagcagatct gcatcccttc attcggttta cgcatctgct ccataccatc ggcacgcaac
      421 cggacgatct cgcccgggcc tataaatttc tcgatctcat aatccaagtt cggaagactg
      481 ctggactcgc tggtcgccgc ataagccccg tctttccttc cgattacgat cggcgtacgc
      541 ccccatttgt cacgggcagc gataatacca tcctccgtca ggagcaacat ggagcaagag
      601 ccctttatct tattgtaaac attctcaatg ccctccacga agtccttacc ttgtgtaatc
      661 agcaaagcga ctaactccgt ctgattcgtt tttcctgaac tcaattccga aaaatgcata
      721 ttcgccttca ataactcatc ctccaattcg tccaagttat tgatcttcgc caccgtcacg
      781 atcgcaaatt ttcctaagtg agagttgata acgattggct gcgcatccgt atcgctgata
      841 ataccgaccc cggcatttcc tttgaattta ggaagccccg gttcaaactt ggtgcggaaa
      901 taagaattct ccagattgtg gatcgaacgc gtaaatcctt cttccttatc gtacgtagcc
      961 ataccgcctc tgcgggttcc tagatgagaa ttgtagtccg taccatagaa taaatccgta
     1021 atacagtctc cattagaaat agttccgaaa aaaccaccca ttgtttttta tgtttgtatt
     1081 tatgtttgag accacaaagt tacaagttta tttatatatg ttccaaaatt tacttcataa
     1141 cgtttattat catcgacaat aaaaaaagga tacccctttt cgggatatcc ttttccttat
     1201 tctttggtcg cagaaactta agcctcagca acaacttctt ttacagaaac gaatgatctg
     1261 ttttcttttc ccctacggaa agtaacaacg ccatctacca acgcatacaa cgtatgatcc
     1321 ttaccgatac ctacgttctc gcccggatga tgaaccgtac ctctttgacg aacgatgatg
     1381 ttaccagctt tagcaacctc accaccaaaa agcttaacac ctaatctttt actttgtgat
     1441 tcacggccgt tcttagaact acccacacct ttcttatgtg ccatttcttt tcttctcctt
     1501 taaacgttaa gcaataactt ctttaatact cacctcagtg aactgctgac ggtgaccgtt
     1561 caatttacgg taaccttttc ttctcttctt gtggaatacc agcaccttgt caccttttac
     1621 cagcggagat aatacctcac atactacctt tgcgccctct acagtaggaa cacccactgt
     1681 tacctcaccg ttgttatcta ctaacaacac cttgtcaaac tccacaacag caccgctttc
     1741 tgcgttctga atgtgatgaa cgaacaattt cttgccttgc tcagccttga actgttgtcc
     1801 gttaatttct acgattacgt acatctgtct taaaatcttt taaacaggtt aggtcccggg
     1861 ggtgggctcc gtctccggct ccacttattt accctctgcg gaaaatcgag tgcaaagata
     1921 gagtttttta tttaattcca caaacatctt cttgaacttt
//
LOCUS       DBMDTB010000225         1804 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_14103_length_1804_cov_11.371110, whole genome shotgun
            sequence.
ACCESSION   DBMDTB010000225 DBMDTB010000000
VERSION     DBMDTB010000225.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 1804)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 1804)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1804
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_14103_length_1804_cov_11.371110"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(177..1337)
                     /locus_tag="ACZPB4_17165"
     CDS             complement(177..1337)
                     /locus_tag="ACZPB4_17165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 130 protein"
                     /protein_id="HIR1099979.1"
                     /translation="MIKETLLASAFGLLGLVTVACGFQKKDQMVEAVSETASETAWCL
                     DGFVRPAGVNPVIKPLPTKFYCPMREDSVAWEESDTFNPAATIYDGKIVVMYRAEDNS
                     AQGIGSRTSRLGYATSTDGIHFERDTEPVFYPAKDNQAENECPGGTEDPRIAMTEDGT
                     YVLLYTQWNRKVPRLAVATSKDLKHWTKFGPAFEKAYNGKFKDEATKSASLVTTLKGD
                     KQVIAKVNGKYFMYWGEKNVYAATSDNLTDWDPLLDENGELLKLFSPRSGYFDSQLTE
                     CGPPAILTKDGIVLLYNGKNEPGEKGDTAYPANSYCAGQALFDVNNPKKLIGRLDKPF
                     LQPTDDFEKSGQYPAGTVFVEGLVYYQNKWYLYYGCADSFVAVAVSDKQLNF"
     gene            complement(1395..>1804)
                     /locus_tag="ACZPB4_17170"
     CDS             complement(1395..>1804)
                     /locus_tag="ACZPB4_17170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="alpha-L-rhamnosidase C-terminal
                     domain-containing protein"
                     /protein_id="HIR1099980.1"
                     /translation="IDQGASTTWEYWSGERSKVHNCFNGIGAWFCQAIGGILPDEDRP
                     GYKHFFIKPQVPDGVTWARVARETPYGTARVSWTMENRSLSLDLEIPANSTATFIAPF
                     NVSNCVLDGNNVEISAGSILLESGKHTLSLPAE"
BASE COUNT          476 a          504 c          354 g          470 t
ORIGIN      
        1 tccgtattcg tactcgcccc gataaaggga tttacataat cagagaaatg aacctcctcg
       61 atagtccggg tcggaccgga acaggcagtt cccaccaacg cgagcgataa cgccgtggtc
      121 gttatccatt tcaagtttct tgcaagttgt atcattattt ctatcctcat tatactttaa
      181 aaattcaatt gtttatccga tacggctacc gccacgaatg aatcggcaca gccataatac
      241 agataccatt tattctggta atagaccagt ccttccacga ataccgtacc cgcagggtat
      301 tggccgcttt tctcaaagtc atccgtcggt tgcaagaaag gcttatccag acggccgatc
      361 aatttcttcg ggttatttac atcgaacaat gcttgtccgg cacaataaga gttcgccgga
      421 taagcagtat cccctttttc tcccggttcg tttttaccat tatacaacag gacgatacca
      481 tccttcgtca agatagcggg aggtccacat tcggtcaact ggctatcgaa atagccggaa
      541 cggggagaga acaatttaag caactcacca ttctcgtcca acagtgggtc ccaatcggtc
      601 aaattatcgg aggtagccgc atatacgttc ttttcccccc agtacatgaa atacttgcca
      661 ttcactttcg caatgacctg cttatctccc tttaaagtcg tgactagcga tgcggattta
      721 gtcgcctcat ccttgaattt accattatag gctttctcaa aagccggacc gaacttcgtc
      781 cagtgtttca aatccttcga ggtcgccacc gccagacgag gcaccttgcg gttccattgc
      841 gtatacagca agacatacgt accatcctcg gtcatagcga tacgtggatc ttccgtacct
      901 ccgggacatt cgttctccgc ttgattatct ttagccggat aaaaaacagg ctccgtatcc
      961 ctctcaaaat ggataccgtc agtagaggtc gcgtatccca aacgggaagt ccgggaaccg
     1021 attccttgag cggagttatc ttccgcacgg tacatcacca cgatcttccc atcgtaaatc
     1081 gtagccgccg gattaaatgt gtcactctcc tcccatgcta cagaatcttc ccgcatcggg
     1141 caataaaact tagttggcaa tggcttaatt accggattca caccagccgg acgcacaaac
     1201 ccgtccaagc accaagccgt ctccgatgca gtttccgaca cagcttccac catctgatct
     1261 ttcttttgaa agccgcaagc tacggtcacc aatcccaata aaccgaaagc agaggctaat
     1321 aatgtttctt taatcatgtt atattcgtag tattaagtta tatttatttc caaaagaagg
     1381 gaatcatatg attcctattc cgcaggcagc gatagcgtgt gttttccact ttccaacaga
     1441 atcgaacccg ccgatatttc tacattattc ccatctaaca cacaattcga tacgttaaat
     1501 ggagcgataa aggtcgccgt actattcgca ggtatctcca gatcaaggga aagcgatcgg
     1561 ttctccatag tccaagacac acgtgccgta ccgtaagggg tctctctcgc caccctcgcc
     1621 cacgtcacgc catccggcac ttgcggtttg ataaagaaat gtttatagcc cggcctatcc
     1681 tcatccggca agatccctcc gatcgcctga cagaaccaag cgccaatgcc attgaaacaa
     1741 ttatgaacct tactacgttc tcccgaccag tattcccaag tcgtagaagc cccttgatcg
     1801 atca
//
LOCUS       DBMDTB010000226         1762 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_14569_length_1762_cov_7.734497, whole genome shotgun sequence.
ACCESSION   DBMDTB010000226 DBMDTB010000000
VERSION     DBMDTB010000226.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 1762)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 1762)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1762
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_14569_length_1762_cov_7.734497"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..635)
                     /locus_tag="ACZPB4_17175"
     CDS             complement(<1..635)
                     /locus_tag="ACZPB4_17175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent transcriptional regulator"
                     /protein_id="HIR1099981.1"
                     /translation="MLSILIVEDDITFSLMLTTWLGKKGFVVISSSSVSDAKRRLGEE
                     AFDLVISDLRLPDSDGIDLLKWLKNTHPSLPLIMMTSYAEIQTAVQAMKLGAADYIAK
                     PLNPDELLGKIRELAHVEEKAPARVPVPSAPDLYIEGQSQAARQLYEHVRLVAPTDMS
                     VLVTGASGTGKEYIARRIHEQSNRSKAPFVAVDCGAIPKELAASEFFGHVKG"
     gene            complement(686..>1762)
                     /locus_tag="ACZPB4_17180"
     CDS             complement(686..>1762)
                     /locus_tag="ACZPB4_17180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF418 domain-containing protein"
                     /protein_id="HIR1099982.1"
                     /translation="HFNLYNFPEATTDFMKALDKGVWDTLFFLFSGKAYAIFALLFGF
                     SFFIQFDNQARKGKDFRLRFFWRLVLLFFIGCFNASFFPGEILVLYSILGIVLIPVCK
                     LSNKVVLAIAVVLMLQPMEWGKFMYALMHPEYVASKEQWLVHCMRIYPYMEGTSFWEM
                     VKSNLWDGQLYSLLWAWSYGRFFQTSALFMLGMLLGRKGLFVDLEKHRTFWTRTFVIG
                     VVCFIPLYYLSLSLPGLLERTEELRPMSTIVSSLRNFSFMCVLVSSFIFLWQWKAPHK
                     VLHGLVPYGKMSLTNYLTQSMVGSFIYFGYGLSLYDDLGTTASFAVGILLFILQLGFC
                     HWWLAHHKQGPFEGVWRKATWMFS"
BASE COUNT          535 a          493 c          384 g          350 t
ORIGIN      
        1 cctttcacgt ggccgaagaa ctcggaagcc gccaattcct tggggatagc gccgcaatcc
       61 acggcgacaa acggagcctt gctacgatta ctttgctcgt ggatccgacg ggcgatatac
      121 tccttaccgg taccgctagc gccggtcacc aataccgaca tatccgtcgg agccaccaaa
      181 cgcacatgct cataaagctg gcgggccgct tggctctgcc cctcgatata aagatccggg
      241 gccgagggaa ccgggactct cgccggagcc ttctcctcca cgtgcgcaag ctccctgatc
      301 tttcccagca actcatccgg gttcagcggc ttggcaatat aatccgccgc ccccagcttc
      361 atcgcctgaa ccgccgtttg tatctccgca taactggtca tcatgataag gggtaaggaa
      421 ggatgggtat tcttcagcca tttcaataag tcgatcccgt cactatccgg caggcgtaaa
      481 tccgatataa ccaaatcgaa cgcttcctcc cccagcctcc gtttagcatc ggaaacagag
      541 gacgaggata ttacgacaaa ccctttctta cccagccatg tggtaagcat caaggaaaaa
      601 gttatatcat cttcaacgat tagaatcgac aacataccca ctcagattat ttatagtaac
      661 cacaaaggta aataaataaa acgaatcaag aaaacatcca cgtagcttta cgccatactc
      721 cctcgaaagg accttgttta tgatgggcta accaccagtg gcaaaaacct agctggagaa
      781 tgaaaagaag gattcctacg gcgaagctgg cggtcgtccc cagatcgtca tacagggata
      841 aaccgtatcc gaaatagata aaagagccta ccatcgattg cgtgaggtaa ttcgtcaagc
      901 tcattttccc gtaaggcaca agcccgtgaa gcaccttatg cggcgccttc cactgccaca
      961 agaagataaa ggaggatacc aatacgcaca tgaacgagaa attacgcaag gaagacacga
     1021 tcgtgctcat cgggcgaagc tcttcggtac gctccagcaa accgggtagg gaaagggaca
     1081 gataatagag gggaatgaaa caaactaccc cgataacaaa ggtccttgtc caaaacgtcc
     1141 ggtgcttctc cagatcgaca aacaatccct tgcgtcccaa caacatgccc agcataaaga
     1201 gagccgatgt ctggaagaaa cgtccatagc tccaagccca gagaaggcta tacagctgcc
     1261 cgtcccacag attggacttg accatttccc aaaagctggt accttccata tacggataga
     1321 tccgcataca gtgcaccagc cattgttcct tggatgccac atattccgga tgcatcaggg
     1381 catacatgaa tttaccccac tccataggct gtagcatcaa gaccacggcg atcgccaaga
     1441 ccaccttatt actcaacttg caaaccggta tcaacacaat acccaagatc gaataaagca
     1501 ccaagatctc ccccgggaag aacgatgcgt tgaagcaacc gataaagaat aggagcacca
     1561 accgccagaa aaaacgaagc cggaagtcct tccctttcct cgcttggtta tcaaactgga
     1621 taaagaagct aaaaccgaac agcagggcga aaatagcgta cgccttcccg gaaaagagga
     1681 agaacaaggt atcccatacc cctttatcca aggctttcat aaaatcggta gtagcctccg
     1741 gaaaattata caagttaaaa tg
//
LOCUS       DBMDTB010000227         1760 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_14594_length_1760_cov_8.343580, whole genome shotgun sequence.
ACCESSION   DBMDTB010000227 DBMDTB010000000
VERSION     DBMDTB010000227.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 1760)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 1760)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1760
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_14594_length_1760_cov_8.343580"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..513
                     /locus_tag="ACZPB4_17185"
     CDS             <1..513
                     /locus_tag="ACZPB4_17185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UvrB/UvrC motif-containing protein"
                     /protein_id="HIR1099983.1"
                     /translation="VNLLREGLDLPEVSLVAILDADKEGFLRSHRSLTQTAGRAARNV
                     NGKVIFYADKITASMQQTMDETNRRREKQMAYNEAHGITPKQVMKNSVSMLAEKQQTA
                     EPYAYIEPEPSLVADPVVQYMNRTQLEKAIERTRKQMTEAAKKLDFIEAAQFRDELVK
                     LEDLLKTKKD"
     gene            517..1389
                     /locus_tag="ACZPB4_17190"
     CDS             517..1389
                     /locus_tag="ACZPB4_17190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase-like
                     domain-containing protein"
                     /protein_id="HIR1099984.1"
                     /translation="MRRGMLLLGFWMCVCMVFLVNAQEHTSRKLYCTDEDRAIFDRYC
                     TQMEPKKSLPLDKLMIHTALFFRGTPYVASTLEKEPEGLVVNLRELDCTTFAESVLAL
                     SRTLWEENPTFENFCENLQQLRYRDGTIHDYTDRLHYMTDWFYENERKGIVKDMGREI
                     GGASLPLDLSFISTHPDSYKQLKNHPERVRRMADKEKEINLRPHYYVPKQEIEKCSSG
                     IKNGDILCFVTSIKGLDVTHVGIAYWKDGQLTFIHASSSAKKVIIQVSSLRDYAEGIK
                     SCKGILVARPLSIH"
     gene            complement(1383..>1760)
                     /locus_tag="ACZPB4_17195"
     CDS             complement(1383..>1760)
                     /locus_tag="ACZPB4_17195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5686 family protein"
                     /protein_id="HIR1099985.1"
                     /translation="DFRYFTRRNFPDTWDDQIGGVFNLLKGEWFNASDKYIQAHFMYE
                     SPFVLFKILRINSTKKFMQTASRYILSERFYLSQLWTPVLPSYTEVGYGIGNHIFNIG
                     IFAGFDRWHYQSMGFKFAFELFQ"
BASE COUNT          477 a          383 c          468 g          432 t
ORIGIN      
        1 gtcaacttgc tacgcgaggg gctggattta ccggaagtct cgttggtcgc tatcttggat
       61 gcggataagg aaggcttttt gcgttcccac cgatccttga cgcagacagc tggacgtgcc
      121 gcccgaaacg tgaatggaaa ggttatcttc tatgccgata agatcacggc gagtatgcag
      181 cagaccatgg acgagaccaa tcgccggcgg gagaaacaga tggcttataa cgaggcgcat
      241 ggcattactc cgaagcaagt catgaaaaac agtgtatcca tgcttgccga gaaacaacaa
      301 acggcggagc cttacgctta tatagagccg gaaccaagct tggtagcgga cccggtcgtg
      361 caatacatga accgtacgca gcttgagaag gcgatcgagc ggactcgcaa acagatgaca
      421 gaggcggcga agaaactgga tttcatcgag gctgcccaat tccgtgacga gctggtgaaa
      481 ttggaggatt tactgaaaac gaaaaaggat tagcttatga gaaggggaat gctactgctc
      541 ggtttttgga tgtgtgtatg tatggtgttt ttagtgaacg cccaagagca tacatcccgt
      601 aagttgtatt gtacggatga ggatcgtgct attttcgatc ggtattgtac tcagatggaa
      661 cctaagaagt cgttacccct agacaagcta atgatccata ccgccctttt cttccggggg
      721 actccttatg tcgcctctac cttggaaaag gagccggagg gcttggtggt taatctgcgg
      781 gaactggatt gtaccacatt cgcggagagc gtattggctt tatcccgcac cctgtgggaa
      841 gaaaatccta cctttgagaa cttctgtgag aatttacagc agctccggta cagagacggc
      901 acgatccatg attacacgga tcgtttgcat tatatgaccg actggttcta tgagaacgag
      961 cgaaaaggaa tcgtgaaaga tatggggcgg gagatcggtg gtgcctccct acctttggat
     1021 ttatctttta tatccacgca tccggatagc tataagcaat tgaagaacca tccggaaagg
     1081 gttcgaagga tggccgataa ggaaaaggag ataaacctgc gtcctcatta ttatgtgcct
     1141 aaacaggaga tcgagaaatg ttcgtccgga atcaagaatg gcgatatcct ctgttttgtt
     1201 acttctatca aggggctgga cgtgacgcat gtcgggatcg cctattggaa ggatggacaa
     1261 ctgacattta tccatgcctc ttcttccgct aaaaaggtaa tcatccaagt atcctcctta
     1321 cgagattacg ccgaggggat aaagagctgt aaagggatat tggtagcccg cccgctatcc
     1381 attcattgaa ataactcgaa ggcaaacttg aatcccatgc tttggtaatg ccagcgatcg
     1441 aatccggcga atatcccgat attaaagata tggttcccga tcccgtatcc gacttccgta
     1501 tagctaggca agaccggtgt ccatagctgg ctcagataaa agcgttcgga gaggatatag
     1561 cgtgaggccg tttgcatgaa ttttttcgtg gagttgatgc ggaggatctt gaataagaca
     1621 aaagggcttt catacatgaa atgcgcttgt atatacttat cggaggcatt gaaccactcg
     1681 cctttcagca gattgaagac tccgccgatc tgatcatccc atgtatcggg gaaattcctg
     1741 cgggtgaaat acctaaagtc
//
LOCUS       DBMDTB010000228         1685 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_15450_length_1685_cov_11.535354, whole genome shotgun
            sequence.
ACCESSION   DBMDTB010000228 DBMDTB010000000
VERSION     DBMDTB010000228.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 1685)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 1685)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1685
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_15450_length_1685_cov_11.535354"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            179..829
                     /locus_tag="ACZPB4_17200"
     CDS             179..829
                     /locus_tag="ACZPB4_17200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005861218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HIR1099986.1"
                     /translation="MASDDIKQAWKVPEPTLRRLPWYLAFVKLMKGKGEAFISSTQIA
                     KEINVDPSQVAKDLSFVNISGKTRVGYDINALVDVLEDFLGFTSQHKAFLFGVGSLGA
                     SLLHDTGLSQYGLEIVAGFDVREDLDGSMINGIPVFHMDDFPAKQKEYGATIGVITVP
                     VEKAQEVTDRIIEGGIKALWNFTPFRIRVPEHIVVQNTSMYAHLAVMFNRLNSMNH"
     gene            833..1447
                     /locus_tag="ACZPB4_17205"
     CDS             833..1447
                     /locus_tag="ACZPB4_17205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004288309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HIR1099987.1"
                     /translation="MKIIAVGMNYAAHNKELHHSLELSEPTIFMKSDSSLLKDGKPFF
                     IPDFSSEVHYETEIVVRIDRLGKNIAERFAHRYYNEVTVGIDFTARDLQNKLRAQGLP
                     WEISKAFDNSAVIGTFIPLEQAGDVNRLPFHLDINGSKVQEGNTSNMLFSVDKIIAYV
                     SRFFTLKIGDLIYTGTPAGVGPVKIDDHLEGYLGERKLLDFYVR"
     gene            1444..>1685
                     /locus_tag="ACZPB4_17210"
     CDS             1444..>1685
                     /locus_tag="ACZPB4_17210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008780684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIR1099988.1"
                     /translation="MRRLIYIFIIGLLLCSYTWADGSRYASNSLLSEGKWVKIRVDKT
                     GIYKLSYADLKNMGFSDPSKVSVHGYGGWPLDEDFS"
BASE COUNT          438 a          297 c          457 g          493 t
ORIGIN      
        1 cgacaacgct aggatcgtca tacttgccgg tatcgaagcc gtgattgttg aatgtgagac
       61 cactgttaag gtggtagtta aatacagttt ctcgatcggg gcttttttgg tgaatctttt
      121 taattttgta cttttgtagg cttgcacgaa tgttatacat gaataggaga attagacaat
      181 ggccagcgat gatataaaac aggcatggaa agtgccggaa cctacgttaa ggaggttacc
      241 gtggtatctt gcgttcgtaa agttgatgaa agggaaaggg gaagcgttta tctcatctac
      301 ccagatcgct aaggagataa atgtagatcc tagtcaggtc gctaaagatc tctcttttgt
      361 gaatatctcc gggaagacga gagtgggata cgatattaac gcgttggttg acgtactgga
      421 ggatttcctc ggttttacat cccagcataa ggcatttctg tttggggtag ggagtctggg
      481 cgcttctttg ttgcatgaca ccggactgag ccaatatggt ttggagatcg tggcgggctt
      541 tgatgtccgt gaggatttgg acgggagcat gatcaatggc attcccgttt ttcatatgga
      601 tgattttcct gccaagcaga aagaatatgg cgcgacgatc ggggtgatca ccgtgccggt
      661 ggagaaagcg caggaggtga cagaccggat tatcgaggga ggaatcaagg ctctttggaa
      721 ttttaccccg ttccgtatac gggtgccgga acatatcgta gtccagaaca cttctatgta
      781 tgcgcattta gctgttatgt ttaatcgatt gaactcaatg aatcactaaa atatgaagat
      841 tatcgccgtt ggaatgaact atgccgctca caataaagag ctgcatcatt cgttagaatt
      901 atcagagcct actattttta tgaagtcgga ctcctctttg ttgaaagatg ggaaaccgtt
      961 ttttattccg gatttttcat cggaagttca ttatgagacg gagatcgtgg tacggataga
     1021 ccgtttgggg aaaaatatag ccgagcgttt cgctcatcgt tattataatg aggttacggt
     1081 cggtattgat ttcacggcac gggatttgca gaataaattg cgtgcgcaag ggctaccgtg
     1141 ggaaattagt aaggcgtttg ataattcggc tgtgatcggg acctttattc cgctggagca
     1201 agcgggggat gtaaaccggc ttccattcca tctggatatc aatggctcga aggtacagga
     1261 aggcaatacc tcgaatatgc tgttttcggt agataagatt attgcgtatg taagtcgctt
     1321 ctttacgctg aaaataggcg atttgattta taccggaaca cctgctggcg taggtcccgt
     1381 gaagatcgac gatcatctgg agggatatct tggcgagcgg aagcttctgg atttttatgt
     1441 gagatgagaa gattaatata tatattcatt ataggtttat tactttgctc atatacatgg
     1501 gcggatggta gccgttatgc ttctaactcc ctgttatcgg aagggaaatg ggtgaagatc
     1561 cgggtggata agaccggaat ctacaaatta tcctatgcgg atttgaagaa tatgggtttc
     1621 tcggacccat cgaaagtctc tgtccatggc tatggaggat ggcccttgga tgaggatttc
     1681 agtaa
//
LOCUS       DBMDTB010000229         1482 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_18355_length_1482_cov_8.354091, whole genome shotgun sequence.
ACCESSION   DBMDTB010000229 DBMDTB010000000
VERSION     DBMDTB010000229.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 1482)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 1482)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1482
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_18355_length_1482_cov_8.354091"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..174
                     /locus_tag="ACZPB4_17215"
     CDS             <1..174
                     /locus_tag="ACZPB4_17215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HIR1099989.1"
                     /translation="ISMLRSLVFVTFGIIVYPSLFGIQSIWYNVPVAELCTLFISFML
                     VRRELLKEAVLKN"
     gene            complement(197..970)
                     /locus_tag="ACZPB4_17220"
     CDS             complement(197..970)
                     /locus_tag="ACZPB4_17220"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008147592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HIR1099990.1"
                     /translation="MKILILGAGKMGSFFTDLLSFDHEVAVLEKDPKRMRFIYNALRL
                     QNPEEVKDFNPELVINCVTLSYTIEAFKAVMPYLQPYCIISDIASVKTYLKEFYETCG
                     FPYVSTHPMFGPTFANLGQLEKENTIIISEGDHLGKIFFKDIYSSLRLHICEYTFEEH
                     DKVVAYSLGIPFASTMVFAATMKHQDAPGTTFKRHMKIARGLLSEDDYLLTEILFNPR
                     TPRQIERIQEELHILQEIIKDKDSEKMKEYLTKIRKNIE"
     gene            complement(979..>1482)
                     /locus_tag="ACZPB4_17225"
     CDS             complement(979..>1482)
                     /locus_tag="ACZPB4_17225"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005868246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004106 - chorismate mutase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HIR1099991.1"
                     /translation="RMPDLPIFCDPSHIGGKRELVAPLCQQAMDLSFDGLIVESHCNP
                     DCAWSDASQQITPDVLDYVLNLLVIRDVNQTTENLTALRRQIDGIDEQLLELLAKRMR
                     ISKEIGVYKKEHNMPILQSPRYSEILEKRSSMGEQMDLSPDFVKEILKEIHEESVRQQ
                     MIIMNEQ"
BASE COUNT          382 a          335 c          340 g          425 t
ORIGIN      
        1 atctctatgc tgcgtagctt ggtattcgta acctttggta ttatcgttta tccttcttta
       61 ttcggcatcc aaagtatttg gtataatgta ccggtggcgg agttgtgtac gttatttatc
      121 tcctttatgt tggtaaggag agaactttta aaagaggccg tgctgaaaaa ttaatcagca
      181 caaccctctt aatttcttat tcgatattct tccgtatctt cgtcagatac tctttcatct
      241 tctcggaatc cttatccttg atgatttctt gcaagatatg caattcctct tgtatccgct
      301 cgatttggcg aggggtacgg gggttgaaaa ggatctcggt caatagataa tcgtcctcgg
      361 acagaaggcc gcgggcgatt ttcatatggc gtttgaaagt ggtacccgga gcgtcctgat
      421 gcttcatcgt agcggcaaat accatagtgg aggcgaaagg gatacctagt gagtaggcta
      481 ccactttatc gtgctcctcg aacgtgtatt cgcagatatg caggcggagg ctggaataaa
      541 tatccttgaa gaagatcttg cccagatgat cgccctcgga gataataatc gtattctctt
      601 tctccagttg tcccagatta gcgaatgtag gtccgaacat cgggtgagtg gagacatacg
      661 ggaaaccgca tgtctcataa aactccttca aataagtctt cacggaagcg atatcggaaa
      721 taatgcaata cggttgcaag taaggcatca cggccttgaa agcctctatc gtgtaactta
      781 acgttacgca gttgatgacc aactcgggat taaaatcctt aacctcttcc gggttttgta
      841 ggcgaagggc gttatagata aaacgcatac gtttcggatc tttctccaat acggctacct
      901 catgatcaaa actaagcagg tcggtgaaga aagaacccat ctttcctgcg cctaaaatca
      961 atattttcat cttataaatt attgttcgtt catgataatc atttgctggc gcacggattc
     1021 ctcatggatc tccttcaaga tctcctttac aaagtccggg ctcaggtcca tttgttcacc
     1081 catgctggag cgtttctcta agatctcgct gtagcgggga gactgtaaga tcggcatatt
     1141 gtgctctttc ttataaacgc cgatctcctt ggagatacgc atacgtttag ccaaaagctc
     1201 caataattgc tcgtcgatac catcgatctg gcggcgaaga gcggtcaggt tctcggtagt
     1261 ctggtttacg tcacggatca ccaataggtt caatacgtaa tccaatacat ccggggtgat
     1321 ttgctgggaa gcgtcgctcc aagcgcaatc cgggttacaa tgagactcta cgattaagcc
     1381 gtcgaaactc aagtccatcg cttgctggca aagtggggct accaactcac gcttaccacc
     1441 aatgtgacta ggatcacaga aaataggcag gtccggcata cg
//
LOCUS       DBMDTB010000230         1406 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_19724_length_1406_cov_4.347893, whole genome shotgun sequence.
ACCESSION   DBMDTB010000230 DBMDTB010000000
VERSION     DBMDTB010000230.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 1406)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 1406)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1406
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_19724_length_1406_cov_4.347893"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..1105)
                     /gene="uxaC"
                     /locus_tag="ACZPB4_17230"
     CDS             complement(<1..1105)
                     /gene="uxaC"
                     /locus_tag="ACZPB4_17230"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005863439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008880 - glucuronate isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HIR1099992.1"
                     /translation="MKSFLDQDFLLQTDTARELYHEHAAKMPIIDYHCHLDPRQIAEN
                     HQFEDLTEIWLGGDHYKWRAMRANGIPEEYITGDKSPYEKFLKWAETMPYTMRNPLYH
                     WTHLELSRIFGIHKVLNPASAKEIYTTCTDKLRTPEYRAQAIMKRMNVEIVCTTDDPI
                     DSLEYHQKIRSNGCHTRVYPAWRPDKVLAIDNFKALNDYLSKLEEAADKTILTYKHLL
                     EALQKRHDFFAAQGCRLSDHGLDTFYAEPYTEQEIEVIFLKARMGKSLTEQEVRKYRS
                     ALLYELAVMDARSGWVQQFHIGANRNNNKRMFKLLGADTGFDAIDDQPVAVSINRFFS
                     RLDQEGLLAKTIVYNLNPRDTELMVANAYNFNDG"
     gene            complement(1102..>1406)
                     /locus_tag="ACZPB4_17235"
     CDS             complement(1102..>1406)
                     /locus_tag="ACZPB4_17235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005860016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="beta/alpha barrel domain-containing protein"
                     /protein_id="HIR1099993.1"
                     /translation="EIGFAQETGCDLCKIFPAGNVGGPSFVKNIKAPMPWTLIMATGA
                     VEPTEENLSAWFKAGVTCVGMGSKLFPKEAIAGNDWQSITDLCRDALSIIQKYRQV"
BASE COUNT          325 a          343 c          344 g          394 t
ORIGIN      
        1 tgccgtcgtt gaaattgtag gcattggcta ccatcaactc ggtgtcgcgg ggattcaggt
       61 tgtaaacgat cgttttcgct aacagccctt cttgatctaa acggctgaaa aagcggttga
      121 tggaaacagc taccggctga tcatcgatag cgtcgaaacc tgtgtctgct cctaataact
      181 tgaacatccg tttgttatta ttccgatttg cgccgatatg gaattgttgt acccatccac
      241 tccgggcatc catcaccgcc aattcgtata gcaatgccga acggtatttg cgaacttcct
      301 gctccgtgag cgatttaccc atacgagcct tgaggaagat cacctcaatc tcctgctcgg
      361 tataaggttc ggcatagaaa gtatccaacc cgtggtccga taaccggcac ccttgggcgg
      421 cgaagaaatc atgtcgtttt tgtaaagcct ccaataaatg cttgtaggtg aggatggtct
      481 tatcggcagc ctcctccagc ttggacaaat agtcattaag cgccttgaaa ttatcgatag
      541 cgagtacctt gtccggtcgc catgccggat atacacgagt gtggcatccg tttgaacgta
      601 ttttttgatg gtattccaag gaatctatag gatcgtcggt cgtacaaacg atctctacgt
      661 tcatccgttt catgatggct tgcgcacgat actcgggggt acgtagttta tccgtacaag
      721 ttgtgtagat ttccttggcg gaagccggat tcaagacttt atggattccg aatatacggc
      781 taagctccag atgcgtccaa tgataaagcg gatttcgcat cgtgtaaggc atcgtctcgg
      841 cccatttaag gaatttctcg taaggagatt tatctccggt gatatattcc tcgggaatac
      901 cgttcgctct catcgcccgc catttgtaat ggtctccgcc cagccatatc tccgtaagat
      961 cctcgaattg gtgattctcc gctatttgcc ggggatccag atggcaatgg taatcaatga
     1021 tgggcatctt cgccgcatgc tcgtgatata actcacgggc cgtgtcggtc tggagcaaga
     1081 aatcttgatc taaaaagctt ttcatacttg gcgatacttt tgaatgatag ataaggcgtc
     1141 gcggcataaa tcggtaatgg attgccaatc gtttcccgct atcgcttctt tgggaaagag
     1201 tttggatccc attcctacgc aggtcacgcc ggccttgaac caagcggata gattctcctc
     1261 tgtcggctcc acggcaccgg tcgccatgat tagggtccat ggcatgggtg cctttatgtt
     1321 cttgacaaat gagggacctc ctacatttcc ggcggggaat atcttgcaaa ggtcgcaacc
     1381 tgtttcttgg gcaaagccga tctcgg
//
LOCUS       DBMDTB010000231         1344 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_20898_length_1344_cov_9.592116, whole genome shotgun sequence.
ACCESSION   DBMDTB010000231 DBMDTB010000000
VERSION     DBMDTB010000231.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 1344)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 1344)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1344
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_20898_length_1344_cov_9.592116"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            complement(<1..581)
                     /locus_tag="ACZPB4_17240"
     CDS             complement(<1..581)
                     /locus_tag="ACZPB4_17240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009018130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HIR1099994.1"
                     /translation="MISYLQIDKLTKSFGDLVLFEDITFGVAQGQKIGLIAKNGTGKT
                     TLLNIIGGKEDYDSGEVVFRKDLRVGYLEQSPSYPEELTVLQACFHSKNETVRLIAEY
                     EEAMAKEDHSNLEDILTRMDSFKAWDYEQKAKQILGQLKIHNFNQKIGELSGGQLKRV
                     ALANVLITDPELIILDEPTNHLDLEMTEWLEDYL"
     gene            681..1343
                     /gene="ung"
                     /locus_tag="ACZPB4_17245"
     CDS             681..1343
                     /gene="ung"
                     /locus_tag="ACZPB4_17245"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011966666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_function: GO:0016799 - hydrolase activity, hydrolyzing
                     N-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HIR1099995.1"
                     /translation="MNVRIDESWRKRLQEEFDKPYFEQLVTFVKNEYKQAHVLPPGPQ
                     IFHIFNACPFEKVKVVILGQDPYPNPGQYYGVCFSVPDGVAIPGSLMNIFKEIYDDLG
                     KPIPSSGNLDRWVSQGVFPMNSVLTVRAHQTGSHRNRGWETFTDAVIKKLSDERENLV
                     FMLWGSYAKAKISLIDTSQHLVLTTVHPSPRSAEYGFFGCKHFSKANDFLRGKGIPEI
                     DW"
BASE COUNT          363 a          343 c          281 g          357 t
ORIGIN      
        1 agataatctt ccagccattc ggtcatctcc agatccaaat ggttcgtcgg ctcatccaag
       61 ataatcaatt cagggtccgt gatcaagaca ttcgccaagg ctacccgttt caactgtcct
      121 ccggacaatt ccccgatctt ctgattgaag ttatgaatct tcaactgccc gaggatttgt
      181 ttcgcctttt gctcataatc ccacgccttg aagctatcca tacgggtaag gatgtcctcc
      241 agattcgaat gatcctcttt cgccatcgcc tcctcgtact cagcgatcaa ccggacagtc
      301 tcgttcttcg agtggaagca agcctgtagc acggtcagtt cttccggata agaaggtgat
      361 tgctccaaat acccgacccg caggtctttc cggaaaacca cctcacccga gtcgtaatcc
      421 tccttaccac cgataatatt caacaaggta gtcttacccg tcccgttttt agcgatcaac
      481 ccgatcttct gtccttgtgc gactccgaac gttatatcct cgaaaagaac caaatcaccg
      541 aagctcttgg tcagcttatc tatctgaagg taacttatca tgttttctta tttaaattca
      601 aatcggaagg caaacttaca caaaatcctc gaattttaag cttttctccg tacctttggt
      661 ggaagaataa gaaaaacacc atgaatgtta gaatagatga aagttggaga aaacgtctgc
      721 aagaagaatt tgacaagcct tatttcgagc aattggtgac atttgtcaaa aacgaatata
      781 agcaagcgca cgtacttcct cccgggcccc agatattcca tatatttaac gcatgcccgt
      841 ttgagaaggt aaaagtcgtt atcttgggac aagaccccta tccaaatccg gggcaatact
      901 acggggtctg cttctcggta cccgatggcg tggcgattcc cggctccttg atgaatatat
      961 tcaaagagat ctacgatgat cttgggaaac cgatcccttc ctccgggaat ttggatcgtt
     1021 gggtaagcca aggcgtattt ccgatgaatt ccgtcctcac ggtccgtgcc caccaaacag
     1081 gttcgcaccg gaacagggga tgggaaacat tcacggacgc cgttatcaag aaattaagcg
     1141 acgaacggga aaatctagta ttcatgttat ggggtagtta cgcaaaagcc aagatttccc
     1201 ttatcgatac aagccagcat ttggtcctaa cgaccgtaca tccatctccc cgctccgccg
     1261 aatatggttt cttcggttgt aagcatttca gtaaggctaa tgatttctta cggggtaaag
     1321 gcatcccgga aatcgattgg taag
//
LOCUS       DBMDTB010000232         1019 bp    DNA     linear   ENV 29-APR-2026
DEFINITION  MAG TPA_asm: Parabacteroides distasonis isolate MAG1293
            NODE_30313_length_1019_cov_11.087146, whole genome shotgun
            sequence.
ACCESSION   DBMDTB010000232 DBMDTB010000000
VERSION     DBMDTB010000232.1
DBLINK      BioProject: PRJNA1288367
            BioSample: SAMN50508392
            Sequence Read Archive: ERR10114004
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Parabacteroides distasonis (human gut metagenome)
  ORGANISM  Parabacteroides distasonis
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Tannerellaceae; Parabacteroides.
REFERENCE   1  (bases 1 to 1019)
  AUTHORS   Tang,Y., Kuang,J., Xia,X., Yao,C., Zhou,Z., Liu,J., Ren,Z.,
            Ding,K., Li,M., Li,Y., Jiao,F., Zheng,D., Chen,T., Zhao,A., Wan,X.,
            Ji,G., Zhang,S., Zheng,X. and Jia,W.
  TITLE     Targeting microbiota-generated acetaldehyde to prevent progression
            of metabolic dysfunction-associated steatotic liver disease
  JOURNAL   Cell Metab (2026) In press
   PUBMED   41775257
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 1019)
  AUTHORS   Zhang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2025) Department of Pharmacology and Pharmacy,
            The University of Hong Kong, 21 Sassoon Road, Pokfulam 2052, Hong
            Kong
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 05-JUN-2025
            Assembly Method        :: SPAdes v. 4.2.0
            Genome Representation  :: Full
            Expected Final Version :: No
            Genome Coverage        :: 11.2339x
            Sequencing Technology  :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2026 16:51:08
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,451
            CDSs (total)                      :: 3,386
            Genes (coding)                    :: 3,345
            CDSs (with protein)               :: 3,345
            Genes (RNA)                       :: 65
            rRNAs                             :: 1 (5S)
            complete rRNAs                    :: 1 (5S)
            tRNAs                             :: 62
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 16 of 41
            Pseudo Genes (incomplete)         :: 22 of 41
            Pseudo Genes (internal stop)      :: 8 of 41
            Pseudo Genes (multiple problems)  :: 4 of 41
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1019
                     /organism="Parabacteroides distasonis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_30313_length_1019_cov_11.087146"
                     /isolate="MAG1293"
                     /isolation_source="stool; NASH/Fibrosis stage >=2; MASH1"
                     /host="Homo sapiens"
                     /db_xref="taxon:823"
                     /environmental_sample
                     /geo_loc_name="China: Hong Kong SAR"
                     /lat_lon="22.3193 N 114.1694 E"
                     /metagenome_source="human gut metagenome"
                     /note="metagenomic"
     gene            <1..189
                     /locus_tag="ACZPB4_17250"
     CDS             <1..189
                     /locus_tag="ACZPB4_17250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008779698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004371 - glycerone kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HIR1099996.1"
                     /translation="TSDDIKEVLNAGAKAALDGAEATVPMKANFGRARNYGERSIGFA
                     DSGATSWSCMFASFAEVL"
     gene            259..>1019
                     /gene="lsrF"
                     /locus_tag="ACZPB4_17255"
     CDS             259..>1019
                     /gene="lsrF"
                     /locus_tag="ACZPB4_17255"
                     /EC_number="2.3.1.245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009275033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxy-5-phosphonooxypentane-2,4-dione
                     thiolase"
                     /protein_id="HIR1099997.1"
                     /translation="MADLDDLREGADFGLGINCENQSFHVKGAENLPWGMKDRLSRIF
                     NPKTGKAVMLAFDHGFIMGPTSGLERIDLNIVPLIEYADCLMCTRGILQSTIPANTTK
                     PICLRSDAGTSILTDLNDNVLIDIEDAIRMNVSAMAVMLAIGDEAHEAKTVANLYKAV
                     DKASRYNIPVMGVTAVGKQMARDARYFGLASRICAENGANIVKTYYCEGFEKVAAACP
                     VPVVIAGGKKLPEKEALELCYNAINDGAAGVDMGR"
BASE COUNT          246 a          204 c          294 g          275 t
ORIGIN      
        1 acgtcggatg atatcaagga ggtcttgaat gccggcgcta aagcggcgct tgatggagcg
       61 gaggctacgg taccgatgaa agctaacttt ggacgtgccc gtaactatgg tgagcgttcg
      121 attggtttcg ctgatagcgg ggctacttcg tggagctgta tgttcgcttc ttttgcagag
      181 gtgctataaa ataatacaca gcgtgagacg gggcatgccc cgtctctaca aaatataata
      241 atataacgaa taataaatat ggcagattta gatgatttaa gagaaggtgc ggacttcggt
      301 ttaggcatca attgtgagaa ccagagtttc catgtaaagg gagccgagaa cttaccttgg
      361 ggtatgaaag accgtctgtc ccgtatcttc aacccgaaga caggcaaggc ggttatgctt
      421 gcttttgacc atggtttcat catggggccg acctccggtc tggagcgtat cgatttgaat
      481 atcgttcctt tgattgaata tgcggattgc ttgatgtgta cccgtggtat cctgcaatct
      541 acgatccctg cgaatacgac gaaaccgatt tgtcttcgtt cggacgctgg aacgtctatc
      601 cttacggatt tgaacgataa tgtattgatc gatatagagg acgctatccg tatgaacgtc
      661 tccgccatgg cggttatgtt ggctatcggt gatgaggcgc atgaggctaa gactgtggct
      721 aacttatata aggcggtcga taaggccagc cgttacaata tcccggtaat gggtgttacc
      781 gccgttggta agcaaatggc tcgagacgct cgttatttcg gtctggcttc ccgtatctgt
      841 gcggagaatg gcgctaatat cgtgaagacc tactattgtg agggcttcga gaaggtagcc
      901 gctgcttgtc cggttcccgt ggtaattgcc ggtggtaaga aattaccgga gaaggaggcg
      961 ttggaattat gttataatgc gatcaacgac ggtgcggctg gcgtggatat gggacgtaa
//
